# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Keratin PF02422.11 KFM00240.1 - 4.5e-26 90.6 6.3 4.8e-26 90.5 4.4 1.0 1 0 0 1 1 1 1 Keratin DUF35_N PF12172.3 KFM00240.1 - 0.014 15.2 0.2 0.026 14.4 0.1 1.5 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Cornifin PF02389.10 KFM00240.1 - 0.05 13.3 3.3 0.052 13.3 2.3 1.0 1 0 0 1 1 1 0 Cornifin (SPRR) family DUF3432 PF11914.3 KFM00240.1 - 2.1 8.3 8.6 5.6 7.0 5.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3432) zf-H2C2_2 PF13465.1 KFM00241.1 - 2.5e-13 49.5 1.9 3.3e-06 27.0 0.0 2.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFM00241.1 - 1.8e-06 27.9 2.7 1.8e-06 27.9 1.9 2.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM00241.1 - 0.0033 17.6 5.2 0.0065 16.7 1.3 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-AN1 PF01428.11 KFM00241.1 - 0.083 12.7 2.9 0.094 12.6 2.0 1.4 1 1 0 1 1 1 0 AN1-like Zinc finger zf-LYAR PF08790.6 KFM00241.1 - 0.1 12.2 0.2 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger Trypsin PF00089.21 KFM00242.1 - 1.5e-61 207.8 0.1 1.7e-61 207.6 0.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 KFM00242.1 - 5.6e-05 23.1 0.0 8.5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Ion_trans PF00520.26 KFM00243.1 - 8.9e-31 106.6 8.4 8.9e-31 106.6 5.9 1.6 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 KFM00243.1 - 1.6e-09 37.3 6.4 1.6e-09 37.3 4.5 2.7 3 0 0 3 3 3 1 Ion channel PKD_channel PF08016.7 KFM00243.1 - 0.098 11.0 5.8 0.17 10.2 1.9 2.1 1 1 1 2 2 2 0 Polycystin cation channel DUF202 PF02656.10 KFM00243.1 - 0.12 12.6 3.9 41 4.5 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF202) 7tm_1 PF00001.16 KFM00245.1 - 4.9e-07 29.1 1.0 6.8e-07 28.6 0.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PIRT PF15099.1 KFM00245.1 - 0.16 11.2 0.4 0.19 10.9 0.3 1.2 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family DUF4278 PF14105.1 KFM00246.1 - 0.099 12.6 0.7 8.1 6.4 0.0 3.1 2 2 0 2 2 2 0 Domain of unknown function (DUF4278) Gamma-thionin PF00304.15 KFM00246.1 - 9.6 6.3 10.8 1 9.4 1.3 2.9 1 1 0 2 2 2 0 Gamma-thionin family zf-H2C2_2 PF13465.1 KFM00247.1 - 4.1e-41 137.2 53.0 8.7e-07 28.9 0.5 8.9 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.21 KFM00247.1 - 5.2e-33 111.4 55.5 3.3e-05 23.9 0.5 8.2 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KFM00247.1 - 2.6e-20 71.6 58.5 1e-05 25.2 0.4 9.0 9 1 0 9 9 8 7 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KFM00247.1 - 5.1e-20 70.2 56.4 0.0024 18.0 1.1 8.2 8 0 0 8 8 8 8 C2H2-type zinc finger zf-met PF12874.2 KFM00247.1 - 5.1e-10 39.1 28.3 0.05 13.8 0.6 8.2 8 0 0 8 8 8 3 Zinc-finger of C2H2 type XPA_N PF01286.13 KFM00247.1 - 7.7e-09 35.0 11.5 0.53 10.0 0.0 7.8 8 0 0 8 8 8 2 XPA protein N-terminal C1_1 PF00130.17 KFM00247.1 - 3.9e-05 23.2 29.6 0.097 12.4 0.5 5.9 3 2 1 4 4 4 3 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 KFM00247.1 - 4.4e-05 23.1 18.3 17 5.2 0.1 7.9 7 1 1 8 8 8 0 Prokaryotic RING finger family 1 LIM PF00412.17 KFM00247.1 - 6e-05 23.0 24.1 0.028 14.4 0.8 5.2 2 2 1 4 4 4 3 LIM domain zf-C2H2_jaz PF12171.3 KFM00247.1 - 0.0001 22.3 29.3 0.26 11.4 0.3 7.7 8 0 0 8 8 7 2 Zinc-finger double-stranded RNA-binding RRN7 PF11781.3 KFM00247.1 - 0.00026 20.4 30.6 2.4 7.7 0.1 8.2 8 0 0 8 8 8 1 RNA polymerase I-specific transcription initiation factor Rrn7 BolA PF01722.13 KFM00247.1 - 0.0044 16.9 8.6 1.7 8.6 0.2 4.0 4 0 0 4 4 4 2 BolA-like protein Elf1 PF05129.8 KFM00247.1 - 0.0059 16.2 21.6 0.49 10.1 0.1 5.3 1 1 4 5 5 5 2 Transcription elongation factor Elf1 like zf-C2HC_2 PF13913.1 KFM00247.1 - 0.012 15.3 42.4 0.16 11.6 0.1 8.5 8 0 0 8 8 8 0 zinc-finger of a C2HC-type zf-Di19 PF05605.7 KFM00247.1 - 0.051 13.7 29.7 0.56 10.3 1.4 5.4 2 1 3 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.5 KFM00247.1 - 0.098 12.6 36.9 2.2 8.2 0.1 7.7 5 3 2 7 7 7 0 Zinc ribbon domain Baculo_IE-1 PF05290.6 KFM00247.1 - 0.11 12.2 8.1 17 5.0 0.0 4.8 2 1 4 6 6 6 0 Baculovirus immediate-early protein (IE-0) C1_4 PF07975.7 KFM00247.1 - 0.29 11.1 26.9 1.3 9.1 0.7 6.0 1 1 7 8 8 8 0 TFIIH C1-like domain WAC_Acf1_DNA_bd PF10537.4 KFM00247.1 - 0.41 10.8 8.1 16 5.6 0.1 4.0 3 2 1 4 4 3 0 ATP-utilising chromatin assembly and remodelling N-terminal Vps39_2 PF10367.4 KFM00247.1 - 1.1 9.4 23.5 8.4 6.6 0.2 5.8 2 1 4 6 6 6 0 Vacuolar sorting protein 39 domain 2 Desulfoferrod_N PF06397.7 KFM00247.1 - 1.1 8.6 36.0 0.28 10.6 0.4 7.8 8 0 0 8 8 8 0 Desulfoferrodoxin, N-terminal domain zf-met2 PF12907.2 KFM00247.1 - 2.1 8.3 15.8 39 4.3 0.0 7.2 8 0 0 8 8 8 0 Zinc-binding C1_2 PF03107.11 KFM00247.1 - 2.2 8.4 31.8 23 5.2 0.0 7.9 8 0 0 8 8 8 0 C1 domain Ribosomal_L31 PF01197.13 KFM00247.1 - 2.8 7.9 5.2 12 5.9 0.0 3.8 2 2 3 5 5 5 0 Ribosomal protein L31 Zn_ribbon_recom PF13408.1 KFM00247.1 - 3.3 8.0 34.2 2.8 8.2 1.7 5.2 3 3 1 4 4 4 0 Recombinase zinc beta ribbon domain HNH PF01844.18 KFM00247.1 - 5.8 6.8 28.8 0.38 10.6 0.3 7.8 8 1 0 9 9 9 0 HNH endonuclease HypA PF01155.14 KFM00247.1 - 6.3 6.5 23.5 1.6 8.4 2.3 4.6 1 1 5 6 6 6 0 Hydrogenase expression/synthesis hypA family zf-HIT PF04438.11 KFM00247.1 - 9.9 5.9 37.8 6 6.5 0.3 7.9 8 0 0 8 8 8 0 HIT zinc finger Glyco_hydro_76 PF03663.9 KFM00248.1 - 0.066 12.5 0.1 0.082 12.2 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 76 DUF641 PF04859.7 KFM00248.1 - 0.084 12.6 0.0 0.3 10.8 0.0 1.7 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) RBD-FIP PF09457.5 KFM00248.1 - 0.12 12.1 1.4 0.14 11.9 0.2 1.6 2 0 0 2 2 2 0 FIP domain dUTPase PF00692.14 KFM00249.1 - 2.7e-18 65.6 0.0 3.3e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 dUTPase RVP PF00077.15 KFM00249.1 - 0.092 12.6 0.1 0.72 9.8 0.0 2.1 2 0 0 2 2 2 0 Retroviral aspartyl protease BTB PF00651.26 KFM00251.1 - 1.1e-23 83.3 0.0 1.3e-23 83.1 0.0 1.0 1 0 0 1 1 1 1 BTB/POZ domain Keratin PF02422.11 KFM00254.1 - 4.5e-26 90.6 6.3 4.8e-26 90.5 4.4 1.0 1 0 0 1 1 1 1 Keratin DUF35_N PF12172.3 KFM00254.1 - 0.014 15.2 0.2 0.026 14.4 0.1 1.5 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Cornifin PF02389.10 KFM00254.1 - 0.05 13.3 3.3 0.052 13.3 2.3 1.0 1 0 0 1 1 1 0 Cornifin (SPRR) family DUF3432 PF11914.3 KFM00254.1 - 2.1 8.3 8.6 5.6 7.0 5.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3432) Keratin PF02422.11 KFM00255.1 - 4.5e-26 90.6 6.3 4.8e-26 90.5 4.4 1.0 1 0 0 1 1 1 1 Keratin DUF35_N PF12172.3 KFM00255.1 - 0.014 15.2 0.2 0.026 14.4 0.1 1.5 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Cornifin PF02389.10 KFM00255.1 - 0.05 13.3 3.3 0.052 13.3 2.3 1.0 1 0 0 1 1 1 0 Cornifin (SPRR) family DUF3432 PF11914.3 KFM00255.1 - 2.1 8.3 8.6 5.6 7.0 5.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3432) Keratin PF02422.11 KFM00256.1 - 2e-40 136.7 9.6 2.5e-40 136.4 6.7 1.1 1 0 0 1 1 1 1 Keratin TIL PF01826.12 KFM00256.1 - 0.32 11.1 6.6 0.46 10.6 4.5 1.2 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain Keratin PF02422.11 KFM00257.1 - 2.4e-40 136.4 13.7 2.6e-40 136.3 9.5 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 KFM00259.1 - 2.8e-39 133.0 12.7 3.7e-39 132.6 8.8 1.2 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 KFM00260.1 - 1.3e-48 162.9 13.1 1.4e-48 162.8 9.1 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 KFM00261.1 - 8.9e-49 163.4 12.3 9.8e-49 163.3 8.5 1.0 1 0 0 1 1 1 1 Keratin PDEase_I PF00233.14 KFM00262.1 - 7.2e-15 55.3 0.2 7.5e-15 55.3 0.1 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase zf-C2H2 PF00096.21 KFM00263.1 - 5.6e-14 51.5 1.0 4e-06 26.8 0.1 2.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM00263.1 - 1.7e-11 43.8 1.7 8.3e-10 38.4 0.1 2.2 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM00263.1 - 9.9e-10 38.0 1.0 0.00074 19.6 0.0 2.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM00263.1 - 6e-09 35.5 3.9 1.6e-05 24.6 0.1 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM00263.1 - 4.2e-07 29.9 0.1 0.0023 18.0 0.0 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM00263.1 - 5.3e-05 23.2 1.8 0.05 13.8 0.0 2.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type XPA_N PF01286.13 KFM00263.1 - 0.0038 16.8 0.2 0.39 10.4 0.0 2.1 2 0 0 2 2 2 1 XPA protein N-terminal Zn-ribbon_8 PF09723.5 KFM00263.1 - 0.018 15.0 1.1 0.45 10.5 0.9 2.1 1 1 0 1 1 1 0 Zinc ribbon domain zf-BED PF02892.10 KFM00263.1 - 0.022 14.4 0.4 1.9 8.2 0.2 2.1 1 1 1 2 2 2 0 BED zinc finger Prok-RING_1 PF14446.1 KFM00263.1 - 0.029 14.1 0.1 1.8 8.3 0.0 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DZR PF12773.2 KFM00263.1 - 0.063 13.1 0.4 0.099 12.4 0.3 1.3 1 1 0 1 1 1 0 Double zinc ribbon DNA_RNApol_7kD PF03604.8 KFM00263.1 - 0.064 12.7 1.7 0.79 9.2 0.1 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit C1_2 PF03107.11 KFM00263.1 - 0.11 12.5 1.8 3.1 7.9 0.1 2.1 2 0 0 2 2 2 0 C1 domain RRN7 PF11781.3 KFM00263.1 - 0.19 11.2 1.9 0.38 10.2 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 C1_4 PF07975.7 KFM00263.1 - 0.21 11.6 1.0 0.29 11.1 0.7 1.3 1 0 0 1 1 1 0 TFIIH C1-like domain C1_3 PF07649.7 KFM00263.1 - 0.34 10.9 1.5 12 5.9 0.1 2.3 2 0 0 2 2 2 0 C1-like domain zf-ribbon_3 PF13248.1 KFM00263.1 - 0.68 9.2 4.4 3 7.1 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-H2C2_2 PF13465.1 KFM00265.1 - 5e-44 146.4 36.9 6.6e-10 38.7 0.5 6.6 7 0 0 7 7 6 6 Zinc-finger double domain zf-C2H2 PF00096.21 KFM00265.1 - 2.1e-34 115.7 41.0 2.6e-07 30.6 0.3 6.1 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KFM00265.1 - 6.3e-20 70.3 28.9 2.7e-05 23.9 0.1 6.9 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KFM00265.1 - 9.1e-20 69.4 35.9 0.0018 18.4 0.4 6.1 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM00265.1 - 3.1e-12 46.2 13.2 0.64 10.2 0.0 6.4 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 KFM00265.1 - 1.6e-07 31.1 28.0 0.0089 15.9 2.3 6.3 4 2 1 5 5 5 2 Zinc ribbon domain zf-met PF12874.2 KFM00265.1 - 3.4e-07 30.2 22.8 0.33 11.2 0.1 6.3 6 0 0 6 6 6 2 Zinc-finger of C2H2 type C1_1 PF00130.17 KFM00265.1 - 2e-06 27.4 15.8 0.052 13.2 0.1 4.5 3 2 1 4 4 4 3 Phorbol esters/diacylglycerol binding domain (C1 domain) XPA_N PF01286.13 KFM00265.1 - 1e-05 25.1 21.2 0.6 9.8 0.1 6.1 6 0 0 6 6 6 1 XPA protein N-terminal Prok-RING_1 PF14446.1 KFM00265.1 - 1.4e-05 24.7 14.8 2.5 7.8 0.0 6.1 5 1 0 5 5 5 1 Prokaryotic RING finger family 1 zf-CHY PF05495.7 KFM00265.1 - 0.00029 20.9 14.8 0.0036 17.4 2.6 3.2 2 1 1 3 3 3 2 CHY zinc finger DZR PF12773.2 KFM00265.1 - 0.00034 20.3 16.2 0.75 9.6 1.4 3.8 1 1 2 3 3 3 2 Double zinc ribbon A2L_zn_ribbon PF08792.5 KFM00265.1 - 0.0009 18.6 20.2 0.06 12.8 0.0 5.8 6 0 0 6 6 6 1 A2L zinc ribbon domain FYDLN_acid PF09538.5 KFM00265.1 - 0.0011 19.4 8.7 1.7 9.2 0.4 5.2 1 1 3 4 4 4 1 Protein of unknown function (FYDLN_acid) COX5B PF01215.14 KFM00265.1 - 0.002 17.8 15.2 2.5 7.7 0.3 5.0 1 1 3 5 5 5 1 Cytochrome c oxidase subunit Vb LIM PF00412.17 KFM00265.1 - 0.0029 17.6 17.4 2.2 8.4 0.2 5.1 2 2 1 4 4 4 1 LIM domain zf-Di19 PF05605.7 KFM00265.1 - 0.0033 17.5 20.1 0.055 13.6 1.8 3.7 2 2 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding CpXC PF14353.1 KFM00265.1 - 0.0034 17.3 15.6 4 7.4 0.8 5.7 2 2 0 4 4 4 0 CpXC protein zf-trcl PF13451.1 KFM00265.1 - 0.0042 16.6 20.0 5.8 6.6 0.0 6.0 6 0 0 6 6 6 0 Probable zinc-binding domain C1_4 PF07975.7 KFM00265.1 - 0.005 16.8 18.9 1.5 8.9 0.4 5.0 1 1 4 5 5 5 1 TFIIH C1-like domain HypA PF01155.14 KFM00265.1 - 0.0054 16.4 13.6 0.53 9.9 0.1 3.3 1 1 2 3 3 3 2 Hydrogenase expression/synthesis hypA family YhfH PF14149.1 KFM00265.1 - 0.0059 16.3 16.4 21 5.0 0.1 6.0 6 0 0 6 6 6 0 YhfH-like protein TFIIS_C PF01096.13 KFM00265.1 - 0.0079 15.8 21.3 5 6.8 0.1 6.2 6 0 0 6 6 6 0 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.2 KFM00265.1 - 0.0092 15.7 2.2 0.0092 15.7 1.5 4.8 4 1 0 4 4 4 1 Transposase zinc-ribbon domain FYVE PF01363.16 KFM00265.1 - 0.036 13.9 23.8 0.84 9.5 5.4 4.3 1 1 1 2 2 2 0 FYVE zinc finger zf-RING_3 PF14369.1 KFM00265.1 - 0.038 13.9 19.9 0.94 9.5 0.1 5.4 6 0 0 6 6 5 0 zinc-finger zf-UBP PF02148.14 KFM00265.1 - 0.047 13.8 16.1 9.9e+03 -3.3 11.2 4.3 1 1 0 1 1 0 0 Zn-finger in ubiquitin-hydrolases and other protein DUF2256 PF10013.4 KFM00265.1 - 0.05 13.3 21.9 0.14 11.9 0.4 5.9 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) ADK_lid PF05191.9 KFM00265.1 - 0.056 13.1 20.3 5 6.8 0.1 5.8 4 2 0 4 4 4 0 Adenylate kinase, active site lid zf-AN1 PF01428.11 KFM00265.1 - 0.062 13.1 26.4 5 7.0 0.1 6.3 5 1 1 6 6 6 0 AN1-like Zinc finger BolA PF01722.13 KFM00265.1 - 0.09 12.7 1.1 21 5.1 0.1 3.3 2 2 1 3 3 3 0 BolA-like protein Rad50_zn_hook PF04423.9 KFM00265.1 - 0.13 11.7 0.5 0.13 11.7 0.3 3.9 5 0 0 5 5 3 0 Rad50 zinc hook motif zf-LYAR PF08790.6 KFM00265.1 - 0.15 11.7 0.2 0.15 11.7 0.2 5.2 6 0 0 6 6 5 0 LYAR-type C2HC zinc finger zf-RING_5 PF14634.1 KFM00265.1 - 0.16 11.7 17.5 2.5 7.8 1.4 4.2 2 2 1 3 3 3 0 zinc-RING finger domain TF_Zn_Ribbon PF08271.7 KFM00265.1 - 0.2 11.0 21.9 0.22 10.8 0.9 5.2 5 1 0 5 5 5 0 TFIIB zinc-binding zf-ribbon_3 PF13248.1 KFM00265.1 - 0.21 10.8 24.9 3.2 7.0 0.2 6.1 6 0 0 6 6 6 0 zinc-ribbon domain zinc-ribbons_6 PF07191.7 KFM00265.1 - 0.22 11.3 15.6 3.6 7.4 0.6 5.2 3 2 2 5 5 5 0 zinc-ribbons zinc_ribbon_5 PF13719.1 KFM00265.1 - 0.29 10.7 22.2 18 5.0 2.0 5.8 4 2 1 5 5 5 0 zinc-ribbon domain C1_3 PF07649.7 KFM00265.1 - 0.33 11.0 19.7 8.8 6.4 0.1 6.1 6 1 0 6 6 6 0 C1-like domain DUF2072 PF09845.4 KFM00265.1 - 0.34 10.8 19.3 10 6.0 0.1 5.0 4 2 0 4 4 4 0 Zn-ribbon containing protein (DUF2072) DNA_RNApol_7kD PF03604.8 KFM00265.1 - 0.45 10.0 24.2 4.5 6.8 0.1 6.1 5 1 1 6 6 6 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_2 PF13240.1 KFM00265.1 - 0.52 9.8 25.1 8.2 6.0 0.1 5.7 4 2 1 5 5 5 0 zinc-ribbon domain UPF0547 PF10571.4 KFM00265.1 - 0.54 9.9 25.6 1.9 8.2 0.2 6.0 6 0 0 6 6 6 0 Uncharacterised protein family UPF0547 RRN7 PF11781.3 KFM00265.1 - 0.72 9.4 13.4 3 7.4 0.0 4.8 5 0 0 5 5 5 0 RNA polymerase I-specific transcription initiation factor Rrn7 PHF5 PF03660.9 KFM00265.1 - 0.84 9.7 7.5 1.2 9.2 0.3 3.0 1 1 2 3 3 3 0 PHF5-like protein zinc_ribbon_4 PF13717.1 KFM00265.1 - 0.91 9.2 21.7 14 5.4 1.9 5.8 4 2 1 5 5 5 0 zinc-ribbon domain zf-UBR PF02207.15 KFM00265.1 - 0.95 9.2 20.3 2.5 7.8 6.2 4.4 1 1 1 2 2 2 0 Putative zinc finger in N-recognin (UBR box) Mut7-C PF01927.11 KFM00265.1 - 0.97 9.3 17.9 1.9 8.4 0.3 4.7 1 1 3 4 4 4 0 Mut7-C RNAse domain zf-C2HC_2 PF13913.1 KFM00265.1 - 1 9.0 28.1 3.3 7.4 0.1 6.6 6 1 0 6 6 6 0 zinc-finger of a C2HC-type DUF2175 PF09943.4 KFM00265.1 - 2 8.5 7.0 13 5.9 0.0 3.9 5 0 0 5 5 4 0 Uncharacterized protein conserved in archaea (DUF2175) Chordopox_RPO7 PF05864.7 KFM00265.1 - 2.1 8.4 6.0 4.5 7.4 0.0 3.8 6 0 0 6 6 3 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) DUF2321 PF10083.4 KFM00265.1 - 2.6 7.5 14.5 6.4 6.2 0.1 4.4 1 1 5 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-HIT PF04438.11 KFM00265.1 - 2.9 7.6 25.8 14 5.4 0.2 6.0 6 0 0 6 6 6 0 HIT zinc finger zf-C3HC4_3 PF13920.1 KFM00265.1 - 4.1 7.1 14.0 1.6 8.4 0.4 3.8 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-ISL3 PF14690.1 KFM00265.1 - 4.6 7.3 33.9 3.5 7.7 1.1 6.0 5 1 0 5 5 5 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Elf1 PF05129.8 KFM00265.1 - 7.1 6.3 17.8 0.63 9.7 0.6 4.5 1 1 4 5 5 5 0 Transcription elongation factor Elf1 like SprT-like PF10263.4 KFM00265.1 - 7.6 6.1 22.6 41 3.7 1.1 3.7 1 1 1 2 2 2 0 SprT-like family RRM_1 PF00076.17 KFM00266.1 - 4.9e-19 67.7 0.0 6.6e-19 67.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM00266.1 - 9.6e-13 47.9 0.0 1.2e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM00266.1 - 4.4e-11 42.4 0.0 7.2e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFM00266.1 - 6.1e-06 26.0 0.0 8.8e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.1 KFM00266.1 - 0.093 12.5 0.2 0.18 11.5 0.2 1.5 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Hydrolase PF00702.21 KFM00267.1 - 3e-12 47.4 1.0 4.2e-12 46.9 0.7 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFM00267.1 - 4.5e-05 23.1 1.6 5.8e-05 22.7 1.1 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFM00267.1 - 0.00053 20.2 0.0 0.00093 19.4 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase AvrPtoB-E3_ubiq PF09046.5 KFM00268.1 - 0.058 13.4 0.1 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 AvrPtoB E3 ubiquitin ligase Spot_14 PF07084.7 KFM00269.1 - 2.7e-11 43.6 0.0 3.3e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Thyroid hormone-inducible hepatic protein Spot 14 Histone PF00125.19 KFM00270.1 - 5.9e-12 45.5 0.2 7.8e-12 45.1 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFX_C PF14601.1 KFM00270.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 DNA_binding protein, TFX, C-term zf-C2H2 PF00096.21 KFM00271.1 - 5.3e-10 39.0 9.7 1.2e-05 25.3 1.1 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM00271.1 - 1.6e-07 31.2 8.1 9e-07 28.8 0.3 2.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM00271.1 - 2.2e-07 30.7 6.6 0.0009 19.4 0.2 2.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM00271.1 - 5.7e-07 29.2 7.5 0.0041 16.9 0.4 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM00271.1 - 2e-05 24.5 5.0 0.0036 17.4 0.6 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM00271.1 - 0.0033 17.5 7.6 0.022 14.9 0.8 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type DNA_RNApol_7kD PF03604.8 KFM00271.1 - 0.014 14.8 3.0 0.49 9.9 0.3 2.3 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit C1_1 PF00130.17 KFM00271.1 - 0.037 13.7 1.7 0.32 10.7 1.1 2.0 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) UPF0547 PF10571.4 KFM00271.1 - 0.079 12.6 3.2 2.5 7.8 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Ogr_Delta PF04606.7 KFM00271.1 - 0.095 12.3 2.7 0.17 11.5 1.9 1.5 1 1 0 1 1 1 0 Ogr/Delta-like zinc finger Zn-ribbon_8 PF09723.5 KFM00271.1 - 0.1 12.5 4.6 1.8 8.5 1.9 2.4 1 1 1 2 2 2 0 Zinc ribbon domain DZR PF12773.2 KFM00271.1 - 0.11 12.3 2.8 0.16 11.7 2.0 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-UBP PF02148.14 KFM00271.1 - 0.13 12.3 2.6 0.82 9.8 0.1 1.9 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-LYAR PF08790.6 KFM00271.1 - 0.14 11.9 1.5 5.9 6.6 0.1 2.2 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger HNH PF01844.18 KFM00271.1 - 0.15 11.9 2.9 1.6 8.6 0.1 2.3 2 1 0 2 2 2 0 HNH endonuclease DUF3268 PF11672.3 KFM00271.1 - 0.18 11.9 1.8 0.19 11.8 1.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3268) XPA_N PF01286.13 KFM00271.1 - 0.19 11.4 5.5 3.4 7.4 0.2 2.5 2 1 0 2 2 2 0 XPA protein N-terminal Prok-RING_1 PF14446.1 KFM00271.1 - 0.19 11.4 1.8 6 6.6 0.1 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Zn_ribbon_recom PF13408.1 KFM00271.1 - 0.19 11.9 3.6 8.5 6.7 1.9 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Gmx_para_CXXCG PF09535.5 KFM00271.1 - 0.23 10.4 1.6 0.16 10.9 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (Gmx_para_CXXCG) TFIIS_C PF01096.13 KFM00271.1 - 0.35 10.5 4.1 4.1 7.1 0.2 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) YhfH PF14149.1 KFM00271.1 - 0.4 10.5 6.3 5.5 6.8 0.3 2.2 2 0 0 2 2 2 0 YhfH-like protein DUF2256 PF10013.4 KFM00271.1 - 0.42 10.4 2.2 14 5.4 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Cys_rich_CWC PF14375.1 KFM00271.1 - 0.48 10.3 3.4 1.5 8.8 0.6 2.1 2 0 0 2 2 2 0 Cysteine-rich CWC zf-C2HC_2 PF13913.1 KFM00271.1 - 0.51 10.0 10.7 0.46 10.2 0.3 2.5 2 1 0 2 2 2 0 zinc-finger of a C2HC-type zf-MYND PF01753.13 KFM00271.1 - 0.67 9.8 3.6 1.1 9.2 2.5 1.4 1 1 0 1 1 1 0 MYND finger zinc_ribbon_2 PF13240.1 KFM00271.1 - 0.68 9.4 6.7 3.5 7.2 0.2 2.3 3 0 0 3 3 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 KFM00271.1 - 3.8 6.8 6.7 14 5.0 0.8 2.4 2 1 0 2 2 2 0 zinc-ribbon domain zf-ISL3 PF14690.1 KFM00271.1 - 5.4 7.1 5.8 19 5.3 0.1 2.2 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 A2L_zn_ribbon PF08792.5 KFM00271.1 - 6.2 6.4 8.1 9.2 5.8 0.7 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-BED PF02892.10 KFM00271.1 - 8.5 6.2 7.3 11 5.8 0.4 2.1 2 0 0 2 2 2 0 BED zinc finger zf-C2H2 PF00096.21 KFM00272.1 - 4.2e-14 51.9 6.0 7.9e-08 32.2 0.3 2.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM00272.1 - 4.6e-13 48.7 1.7 1.3e-09 37.8 0.1 2.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM00272.1 - 3.5e-07 30.0 4.2 8.5e-05 22.6 0.3 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger C1_4 PF07975.7 KFM00272.1 - 0.0049 16.8 0.4 0.0061 16.5 0.3 1.1 1 0 0 1 1 1 1 TFIIH C1-like domain Zn_Tnp_IS1595 PF12760.2 KFM00272.1 - 0.032 14.0 2.4 0.041 13.6 1.6 1.2 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Ribosomal_L37ae PF01780.14 KFM00272.1 - 0.039 13.8 0.1 0.039 13.8 0.1 1.2 1 0 0 1 1 1 0 Ribosomal L37ae protein family zf-C2H2_6 PF13912.1 KFM00272.1 - 0.039 13.8 8.1 0.095 12.6 1.3 2.5 2 1 0 2 2 2 0 C2H2-type zinc finger zinc_ribbon_5 PF13719.1 KFM00272.1 - 0.11 12.0 1.2 0.87 9.2 0.8 2.0 1 1 0 1 1 1 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.8 KFM00272.1 - 0.14 11.6 0.9 1.2 8.7 0.1 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Zn-ribbon_8 PF09723.5 KFM00272.1 - 0.16 11.9 1.9 0.37 10.7 0.4 1.9 1 1 1 2 2 2 0 Zinc ribbon domain YhfH PF14149.1 KFM00272.1 - 0.2 11.4 0.1 0.2 11.4 0.1 1.6 2 0 0 2 2 1 0 YhfH-like protein zinc_ribbon_4 PF13717.1 KFM00272.1 - 0.23 11.2 1.1 1.6 8.5 0.8 2.0 1 1 0 1 1 1 0 zinc-ribbon domain zf-H2C2_5 PF13909.1 KFM00272.1 - 0.34 11.2 6.5 18 5.8 0.0 2.8 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 KFM00273.1 - 1.7e-16 59.5 18.6 8.8e-09 35.2 1.9 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFM00273.1 - 6e-11 42.0 21.3 1.6e-06 28.0 1.9 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KFM00273.1 - 3.2e-08 33.1 9.4 4.1e-06 26.4 0.7 3.1 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KFM00273.1 - 9.6e-08 31.8 16.2 0.00077 19.6 1.5 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM00273.1 - 5.2e-07 29.6 13.3 0.00043 20.3 0.3 3.1 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM00273.1 - 6.8e-07 29.2 13.0 0.0016 18.5 0.3 3.2 3 0 0 3 3 3 3 Zinc-finger of C2H2 type C1_1 PF00130.17 KFM00273.1 - 0.00084 19.0 0.5 0.0019 17.9 0.4 1.8 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-CHY PF05495.7 KFM00273.1 - 0.0074 16.4 2.4 0.0099 16.0 1.7 1.3 1 1 0 1 1 1 1 CHY zinc finger Zn_Tnp_IS1595 PF12760.2 KFM00273.1 - 0.022 14.5 6.0 0.3 10.9 4.1 2.1 1 1 1 2 2 2 0 Transposase zinc-ribbon domain C1_4 PF07975.7 KFM00273.1 - 0.03 14.3 2.5 0.19 11.7 1.7 1.9 1 1 1 2 2 2 0 TFIIH C1-like domain zinc-ribbons_6 PF07191.7 KFM00273.1 - 0.078 12.7 2.3 2 8.2 0.1 2.2 1 1 1 2 2 2 0 zinc-ribbons Elf1 PF05129.8 KFM00273.1 - 0.09 12.4 2.1 0.17 11.6 1.5 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like DZR PF12773.2 KFM00273.1 - 0.13 12.1 2.2 0.38 10.5 1.5 1.9 1 1 0 1 1 1 0 Double zinc ribbon Cytochrome_C554 PF13435.1 KFM00273.1 - 0.15 12.1 3.8 0.17 11.9 2.6 1.0 1 0 0 1 1 1 0 Cytochrome c554 and c-prime HypA PF01155.14 KFM00273.1 - 0.17 11.5 1.1 0.18 11.5 0.7 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Prok-RING_1 PF14446.1 KFM00273.1 - 0.22 11.2 3.0 5 6.9 0.0 2.7 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-trcl PF13451.1 KFM00273.1 - 0.22 11.1 1.9 0.9 9.2 0.1 2.2 2 0 0 2 2 2 0 Probable zinc-binding domain A2L_zn_ribbon PF08792.5 KFM00273.1 - 0.22 11.0 4.2 2.5 7.6 0.3 2.4 2 0 0 2 2 2 0 A2L zinc ribbon domain CpXC PF14353.1 KFM00273.1 - 0.25 11.2 0.1 0.25 11.2 0.1 1.9 1 1 1 2 2 2 0 CpXC protein zf-AN1 PF01428.11 KFM00273.1 - 0.26 11.1 9.4 1 9.3 1.8 2.7 1 1 1 2 2 2 0 AN1-like Zinc finger FYVE PF01363.16 KFM00273.1 - 0.35 10.7 6.7 1.1 9.2 4.7 1.9 1 1 0 1 1 1 0 FYVE zinc finger IBR PF01485.16 KFM00273.1 - 0.36 10.7 4.0 12 5.8 2.8 2.2 1 1 0 1 1 1 0 IBR domain C1_2 PF03107.11 KFM00273.1 - 0.51 10.5 4.0 10 6.3 0.5 2.4 2 0 0 2 2 2 0 C1 domain Zn-ribbon_8 PF09723.5 KFM00273.1 - 0.56 10.2 10.0 12 5.9 5.2 2.7 2 1 0 2 2 2 0 Zinc ribbon domain XPA_N PF01286.13 KFM00273.1 - 0.68 9.6 9.4 2.2 8.0 0.2 2.6 3 0 0 3 3 3 0 XPA protein N-terminal OrfB_Zn_ribbon PF07282.6 KFM00273.1 - 0.69 9.6 4.1 0.51 10.0 0.2 2.1 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Transpos_assoc PF13963.1 KFM00273.1 - 1 9.3 5.5 5.2 7.1 0.9 2.0 1 1 1 2 2 2 0 Transposase-associated domain TFIIS_C PF01096.13 KFM00273.1 - 1.2 8.7 4.5 6.9 6.4 0.2 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zinc_ribbon_4 PF13717.1 KFM00273.1 - 1.3 8.7 5.0 2.7 7.7 0.0 2.4 3 0 0 3 3 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 KFM00273.1 - 1.5 8.4 5.2 2.6 7.7 0.0 2.5 3 0 0 3 3 3 0 zinc-ribbon domain Cytochrome_C7 PF14522.1 KFM00273.1 - 1.6 8.4 7.0 2.9 7.5 4.9 1.5 1 1 0 1 1 1 0 Cytochrome c7 LIM PF00412.17 KFM00273.1 - 1.6 8.8 5.6 14 5.8 3.9 2.3 1 1 0 1 1 1 0 LIM domain zf-UBR PF02207.15 KFM00273.1 - 1.7 8.4 5.7 1.6 8.4 0.7 2.2 1 1 1 2 2 2 0 Putative zinc finger in N-recognin (UBR box) PSCyt3 PF07627.6 KFM00273.1 - 1.9 8.3 5.5 4.7 7.1 3.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1588) zf-RING_5 PF14634.1 KFM00273.1 - 2 8.2 5.7 30 4.4 0.5 2.4 1 1 1 2 2 2 0 zinc-RING finger domain zf-LYAR PF08790.6 KFM00273.1 - 6.6 6.5 7.0 5.5 6.7 0.1 2.7 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger Keratin PF02422.11 KFM00274.1 - 3.2e-13 49.4 2.9 3.3e-13 49.4 2.0 1.1 1 0 0 1 1 1 1 Keratin C1-set PF07654.10 KFM00275.1 - 1.1e-14 54.1 0.0 1.4e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin C1-set domain ig PF00047.20 KFM00275.1 - 0.0077 16.3 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 KFM00275.1 - 0.038 14.1 0.0 0.046 13.8 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain C2-set_2 PF08205.7 KFM00275.1 - 0.055 13.3 0.0 0.075 12.9 0.0 1.1 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain zf-H2C2_2 PF13465.1 KFM00276.1 - 3e-15 55.6 13.8 1.5e-08 34.5 0.1 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFM00276.1 - 9.2e-14 50.8 13.9 3.5e-07 30.1 0.7 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM00276.1 - 2.5e-10 39.9 10.9 3.8e-05 23.7 0.4 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM00276.1 - 1.4e-08 34.2 14.4 6.2e-06 25.9 0.4 3.5 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM00276.1 - 5.7e-07 29.5 8.0 0.00026 21.0 0.2 3.2 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM00276.1 - 0.00065 19.8 8.9 0.016 15.4 0.4 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-BED PF02892.10 KFM00276.1 - 0.0029 17.3 8.2 0.0049 16.5 0.3 2.9 2 1 1 3 3 3 1 BED zinc finger C1_1 PF00130.17 KFM00276.1 - 0.0046 16.6 2.9 0.0073 16.0 2.0 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-Di19 PF05605.7 KFM00276.1 - 0.0063 16.6 2.6 0.083 13.0 2.3 2.1 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding XPA_N PF01286.13 KFM00276.1 - 0.016 14.9 3.5 1.2 8.9 0.0 3.0 3 0 0 3 3 3 0 XPA protein N-terminal Zn_Tnp_IS1595 PF12760.2 KFM00276.1 - 0.022 14.5 8.0 0.12 12.1 5.9 1.8 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-C2H2_2 PF12756.2 KFM00276.1 - 0.027 14.5 5.9 1.2 9.3 5.2 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-AN1 PF01428.11 KFM00276.1 - 0.027 14.3 3.6 3.1 7.7 0.1 2.4 2 0 0 2 2 2 0 AN1-like Zinc finger Rpr2 PF04032.11 KFM00276.1 - 0.046 13.6 0.3 0.059 13.2 0.2 1.2 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF3565 PF12088.3 KFM00276.1 - 0.11 12.3 1.3 0.68 9.7 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3565) zf-HIT PF04438.11 KFM00276.1 - 0.2 11.3 3.2 0.77 9.4 0.4 2.3 2 0 0 2 2 2 0 HIT zinc finger C1_4 PF07975.7 KFM00276.1 - 0.24 11.4 5.4 0.89 9.6 3.8 1.8 1 1 1 2 2 2 0 TFIIH C1-like domain LIM PF00412.17 KFM00276.1 - 0.27 11.3 5.3 1.2 9.3 3.9 1.8 1 1 1 2 2 2 0 LIM domain zf-LYAR PF08790.6 KFM00276.1 - 0.37 10.5 6.0 1.4 8.6 0.1 3.2 3 2 0 3 3 3 0 LYAR-type C2HC zinc finger PyrI_C PF02748.10 KFM00276.1 - 0.38 10.2 2.9 3.6 7.0 0.8 2.2 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-trcl PF13451.1 KFM00276.1 - 0.4 10.3 3.5 13 5.5 0.1 2.3 2 0 0 2 2 2 0 Probable zinc-binding domain Zn-ribbon_8 PF09723.5 KFM00276.1 - 0.48 10.4 9.4 3.2 7.7 0.0 2.6 3 0 0 3 3 3 0 Zinc ribbon domain zf-MYND PF01753.13 KFM00276.1 - 1.1 9.2 7.1 1.9 8.4 4.5 1.9 1 1 1 2 2 2 0 MYND finger zf-UBP PF02148.14 KFM00276.1 - 1.6 8.9 7.2 7.5 6.7 5.0 2.2 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zinc_ribbon_2 PF13240.1 KFM00276.1 - 2.1 7.9 7.8 0.52 9.8 0.2 2.7 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KFM00276.1 - 6.9 6.4 7.2 14 5.4 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-H2C2_5 PF13909.1 KFM00276.1 - 7.1 7.0 14.3 11 6.4 2.5 3.7 3 1 0 3 3 3 0 C2H2-type zinc-finger domain Keratin PF02422.11 KFM00277.1 - 5.2e-27 93.6 2.1 5.6e-27 93.5 1.4 1.1 1 0 0 1 1 1 1 Keratin BDV_P40 PF06407.6 KFM00277.1 - 0.13 11.0 0.2 0.14 10.9 0.1 1.0 1 0 0 1 1 1 0 Borna disease virus P40 protein p450 PF00067.17 KFM00278.1 - 5.5e-13 48.2 0.0 6.3e-13 48.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SRCR PF00530.13 KFM00279.1 - 5.1e-28 97.3 3.9 5.7e-28 97.1 2.7 1.0 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 KFM00279.1 - 0.0044 17.2 0.9 0.0057 16.8 0.6 1.4 1 1 0 1 1 1 1 Scavenger receptor cysteine-rich domain Tubulin PF00091.20 KFM00280.1 - 2.3e-18 66.7 0.0 2.5e-18 66.6 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FAD_binding_4 PF01565.18 KFM00282.1 - 4.6e-16 58.5 0.0 4.9e-16 58.4 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain Caudal_act PF04731.7 KFM00283.1 - 1.6e-50 170.9 13.4 1.8e-50 170.8 9.3 1.0 1 0 0 1 1 1 1 Caudal like protein activation region UDPGT PF00201.13 KFM00284.1 - 9.6e-25 87.0 0.0 1e-24 86.9 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Tubulin PF00091.20 KFM00285.1 - 4.9e-10 39.5 0.0 5e-10 39.5 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Cytochrom_B_N_2 PF13631.1 KFM00287.1 - 1.1e-07 31.8 0.0 1.1e-07 31.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Lyase_1 PF00206.15 KFM00289.1 - 3.1e-06 26.6 0.0 3.2e-06 26.5 0.0 1.0 1 0 0 1 1 1 1 Lyase 7tm_1 PF00001.16 KFM00290.1 - 7.6e-09 35.0 14.9 3.2e-08 33.0 10.3 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srbc PF10316.4 KFM00290.1 - 0.0007 18.9 0.1 0.0007 18.9 0.1 2.3 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc 7tm_1 PF00001.16 KFM00291.1 - 2.8e-23 82.4 3.8 3.1e-23 82.2 2.6 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM00291.1 - 0.0015 17.7 3.8 0.0018 17.4 2.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF63 PF01889.12 KFM00291.1 - 0.0039 17.3 0.3 0.0062 16.6 0.2 1.3 1 0 0 1 1 1 1 Membrane protein of unknown function DUF63 ABC2_membrane_5 PF13346.1 KFM00291.1 - 0.0069 15.7 2.6 0.015 14.6 0.3 2.0 2 0 0 2 2 2 1 ABC-2 family transporter protein Gla PF00594.15 KFM00294.1 - 1.7e-15 56.3 0.4 2e-15 56.1 0.3 1.1 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain Sushi PF00084.15 KFM00296.1 - 1.3e-23 83.0 6.0 1.1e-12 48.0 0.3 2.1 2 0 0 2 2 2 2 Sushi domain (SCR repeat) HRM PF02793.17 KFM00296.1 - 0.00017 21.5 3.8 0.0027 17.6 0.0 2.3 2 0 0 2 2 2 1 Hormone receptor domain CBM_14 PF01607.19 KFM00296.1 - 0.012 15.5 5.1 1.3 9.0 0.1 2.3 2 0 0 2 2 2 0 Chitin binding Peritrophin-A domain DUF3601 PF12208.3 KFM00296.1 - 0.077 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3601) OLF PF02191.11 KFM00298.1 - 4.3e-87 291.5 1.8 4.8e-87 291.3 1.3 1.0 1 0 0 1 1 1 1 Olfactomedin-like domain V-set PF07686.12 KFM00299.1 - 8.4e-11 41.7 0.0 9.9e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain V-set_CD47 PF08204.6 KFM00299.1 - 4.4e-06 26.4 0.0 6e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 CD47 immunoglobulin-like domain I-set PF07679.11 KFM00299.1 - 5e-05 23.0 0.0 0.00012 21.8 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 KFM00299.1 - 5.7e-05 23.1 0.4 0.00048 20.1 0.3 2.0 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 KFM00299.1 - 0.00044 20.3 0.0 0.00068 19.7 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain MHC_I PF00129.13 KFM00300.1 - 1.5e-09 37.4 0.0 1.8e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 Gp_dh_C PF02800.15 KFM00301.1 - 2.9e-47 160.0 0.1 3.6e-47 159.7 0.1 1.1 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 KFM00301.1 - 2.1e-14 53.7 0.1 3.2e-14 53.1 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Tmemb_185A PF10269.4 KFM00302.1 - 7.6e-08 32.2 17.0 1.5e-06 28.0 2.9 2.0 1 1 1 2 2 2 2 Transmembrane Fragile-X-F protein Tmemb_185A PF10269.4 KFM00303.1 - 7.6e-08 32.2 17.0 1.5e-06 28.0 2.9 2.0 1 1 1 2 2 2 2 Transmembrane Fragile-X-F protein Oxidored_q3 PF00499.15 KFM00304.1 - 3.7e-12 46.2 10.6 3.7e-12 46.2 7.4 1.3 1 1 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Hydrophob_seed PF14547.1 KFM00305.1 - 1 9.3 9.7 1.7 8.6 6.7 1.5 1 1 0 1 1 1 0 Hydrophobic seed protein TEP1_N PF05386.6 KFM00306.1 - 0.39 10.2 0.0 0.39 10.2 0.0 2.6 3 0 0 3 3 3 0 TEP1 N-terminal domain TIR PF01582.15 KFM00307.1 - 3.2e-35 120.6 0.2 6.2e-35 119.6 0.1 1.5 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.2 KFM00307.1 - 3.1e-14 52.1 16.2 1.5e-08 34.0 1.1 4.8 4 1 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM00307.1 - 1.6e-12 47.0 25.0 1.2e-07 31.3 3.6 3.7 1 1 3 4 4 4 4 Leucine rich repeat TIR_2 PF13676.1 KFM00307.1 - 2.5e-11 43.6 0.0 6.2e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 TIR domain LRR_6 PF13516.1 KFM00307.1 - 3.4e-11 42.0 3.9 0.046 13.7 0.0 5.3 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.28 KFM00307.1 - 1.3e-09 36.7 10.8 0.016 15.1 0.3 6.0 5 1 1 6 6 6 4 Leucine Rich Repeat LRR_7 PF13504.1 KFM00307.1 - 2.2e-06 26.9 12.3 0.2 12.0 0.1 6.0 6 0 0 6 6 6 2 Leucine rich repeat LRRCT PF01463.19 KFM00307.1 - 0.025 14.8 0.0 0.14 12.5 0.0 2.4 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain DUF1863 PF08937.6 KFM00307.1 - 0.072 13.1 0.1 0.51 10.3 0.1 2.2 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) Trypsin PF00089.21 KFM00309.1 - 2.3e-21 76.3 0.0 2.4e-21 76.3 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.21 KFM00310.1 - 1.8e-17 63.6 3.5 2e-17 63.5 2.4 1.0 1 0 0 1 1 1 1 Trypsin Ank PF00023.25 KFM00311.1 - 5.1e-31 104.9 3.5 5.9e-08 32.1 0.0 4.0 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 KFM00311.1 - 2.2e-30 104.8 2.9 3.3e-16 59.4 0.4 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFM00311.1 - 5e-27 93.3 9.1 2.7e-11 43.3 0.5 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFM00311.1 - 2.2e-25 88.5 1.0 3.4e-11 43.3 0.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM00311.1 - 6.6e-18 63.0 2.8 0.00011 22.1 0.2 4.1 4 0 0 4 4 4 3 Ankyrin repeat Mic1 PF07035.7 KFM00311.1 - 0.049 12.9 0.1 0.094 12.0 0.0 1.4 2 0 0 2 2 2 0 Colon cancer-associated protein Mic1-like HCV_NS1 PF01560.12 KFM00311.1 - 0.11 10.9 0.0 0.16 10.4 0.0 1.2 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein E2/NS1 Reo_sigmaC PF04582.7 KFM00312.1 - 0.0064 15.7 13.0 0.082 12.0 1.5 2.9 1 1 1 2 2 2 2 Reovirus sigma C capsid protein TMF_TATA_bd PF12325.3 KFM00312.1 - 0.31 10.7 109.8 0.061 13.0 1.8 8.4 1 1 6 7 7 7 0 TATA element modulatory factor 1 TATA binding zf-RING_2 PF13639.1 KFM00313.1 - 4.1e-15 55.3 6.4 4.7e-15 55.1 4.5 1.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFM00313.1 - 5.1e-12 45.6 5.0 8.7e-12 44.8 3.4 1.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM00313.1 - 6.1e-11 41.8 6.4 8e-11 41.4 4.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM00313.1 - 1.1e-10 40.9 5.8 1.4e-10 40.6 4.0 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM00313.1 - 4.4e-10 39.1 6.6 5.8e-10 38.7 4.6 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 KFM00313.1 - 5e-07 29.2 4.8 1.2e-06 28.0 3.4 1.5 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 KFM00313.1 - 7.4e-06 25.5 3.9 9.4e-06 25.2 1.1 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 KFM00313.1 - 1.6e-05 24.9 5.2 2.6e-05 24.2 3.6 1.3 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 KFM00313.1 - 4.5e-05 23.2 10.2 0.00084 19.1 3.8 2.3 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 KFM00313.1 - 0.00058 19.3 2.3 0.00058 19.3 1.6 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 KFM00313.1 - 0.00097 18.8 1.5 0.00097 18.8 1.1 1.9 1 1 1 2 2 2 1 zf-RING of BARD1-type protein Rtf2 PF04641.7 KFM00313.1 - 0.0011 18.2 3.3 0.0015 17.8 2.3 1.3 1 1 0 1 1 1 1 Rtf2 RING-finger zf-UDP PF14569.1 KFM00313.1 - 0.0024 17.5 3.5 0.0033 17.1 2.4 1.3 1 1 0 1 1 1 1 Zinc-binding RING-finger zf-P11 PF03854.9 KFM00313.1 - 0.0026 17.2 2.4 0.0026 17.2 1.6 2.0 2 0 0 2 2 2 1 P-11 zinc finger FANCL_C PF11793.3 KFM00313.1 - 0.013 15.3 6.5 0.56 10.2 4.5 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain FYVE PF01363.16 KFM00313.1 - 0.02 14.7 2.5 0.02 14.7 1.8 2.2 1 1 1 2 2 2 0 FYVE zinc finger DZR PF12773.2 KFM00313.1 - 0.021 14.6 2.7 0.021 14.6 1.8 2.1 1 1 0 1 1 1 0 Double zinc ribbon DUF1272 PF06906.6 KFM00313.1 - 0.024 14.4 6.6 0.051 13.4 4.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) zf-Apc11 PF12861.2 KFM00313.1 - 0.029 14.1 4.5 0.052 13.3 3.1 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.24 KFM00313.1 - 0.09 12.4 4.9 0.14 11.8 3.4 1.3 1 1 0 1 1 1 0 PHD-finger zf-Nse PF11789.3 KFM00313.1 - 0.11 12.0 7.0 0.43 10.1 4.6 1.8 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zinc-ribbons_6 PF07191.7 KFM00313.1 - 0.11 12.3 7.4 0.45 10.3 5.1 1.9 1 1 0 1 1 1 0 zinc-ribbons TerY-C PF15616.1 KFM00313.1 - 0.22 11.4 6.9 0.67 9.8 4.8 1.7 1 1 0 1 1 1 0 TerY-C metal binding domain Baculo_RING PF05883.6 KFM00313.1 - 0.23 11.2 1.0 0.28 11.0 0.7 1.2 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain Auto_anti-p27 PF06677.7 KFM00313.1 - 0.28 10.9 7.6 4.2 7.2 0.2 3.1 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-C4H2 PF10146.4 KFM00313.1 - 0.43 10.5 2.8 0.59 10.1 2.0 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein DUF329 PF03884.9 KFM00313.1 - 0.61 9.6 8.6 1.8 8.1 0.5 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF329) HypA PF01155.14 KFM00313.1 - 0.76 9.4 5.5 1.2 8.8 3.8 1.5 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family IBR PF01485.16 KFM00313.1 - 0.99 9.3 9.8 14 5.6 6.8 2.5 1 1 0 1 1 1 0 IBR domain Zn-ribbon_8 PF09723.5 KFM00313.1 - 1.2 9.1 7.8 2.2 8.3 3.4 2.3 2 1 0 2 2 2 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.6 KFM00313.1 - 1.7 8.3 5.5 1.4 8.6 0.4 2.2 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Opy2 PF09463.5 KFM00313.1 - 1.7 8.7 12.5 1.8 8.7 0.1 3.0 2 1 1 3 3 3 0 Opy2 protein zf-FPG_IleRS PF06827.9 KFM00313.1 - 2 8.1 8.6 14 5.4 0.3 3.2 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS zf-B_box PF00643.19 KFM00313.1 - 2.1 8.3 9.2 4.8 7.1 0.6 2.9 3 0 0 3 3 3 0 B-box zinc finger zf-C2HC5 PF06221.8 KFM00313.1 - 2.6 7.8 8.3 0.37 10.5 2.5 1.9 1 1 1 2 2 2 0 Putative zinc finger motif, C2HC5-type zf-MIZ PF02891.15 KFM00313.1 - 6.1 6.4 13.2 55 3.3 9.1 2.2 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zf-Di19 PF05605.7 KFM00313.1 - 6.6 6.9 8.5 8.8 6.5 0.4 2.6 1 1 2 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-FCS PF06467.9 KFM00313.1 - 7.8 6.2 11.2 17 5.1 0.3 2.6 2 1 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zinc_ribbon_2 PF13240.1 KFM00313.1 - 8.2 6.0 14.7 2.8 7.5 0.1 3.6 3 1 0 3 3 3 0 zinc-ribbon domain zf-RING_3 PF14369.1 KFM00313.1 - 9.2 6.3 9.7 13 5.9 0.1 2.8 2 1 1 3 3 3 0 zinc-finger Prim_Zn_Ribbon PF08273.7 KFM00313.1 - 9.3 6.4 10.6 0.87 9.7 2.3 2.5 1 1 1 2 2 2 0 Zinc-binding domain of primase-helicase 7tm_1 PF00001.16 KFM00314.1 - 3.4e-35 121.4 6.4 4e-35 121.1 4.4 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM00314.1 - 6e-09 35.4 6.0 7.5e-09 35.1 4.1 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM00314.1 - 0.00061 18.9 9.6 0.00076 18.6 6.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srab PF10292.4 KFM00314.1 - 0.33 9.5 4.3 0.19 10.3 1.9 1.4 1 1 0 2 2 2 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor Cadherin PF00028.12 KFM00315.1 - 1.4e-65 217.6 0.0 1.4e-17 63.7 0.0 4.2 4 0 0 4 4 4 4 Cadherin domain NUC153 PF08159.7 KFM00315.1 - 0.1 12.2 0.0 0.39 10.3 0.0 2.0 2 0 0 2 2 2 0 NUC153 domain SCP2 PF02036.12 KFM00316.1 - 1.4e-09 38.1 0.0 1.6e-09 37.9 0.0 1.0 1 0 0 1 1 1 1 SCP-2 sterol transfer family Cullin_Nedd8 PF10557.4 KFM00317.1 - 1.5e-05 24.6 0.1 0.00011 21.8 0.0 1.9 1 1 0 1 1 1 1 Cullin protein neddylation domain VIT PF08487.5 KFM00318.1 - 4.3e-11 42.5 0.0 5.2e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VIT_2 PF13757.1 KFM00318.1 - 7.3e-06 25.3 0.0 1.1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain UPRTase PF14681.1 KFM00319.1 - 5.9e-30 104.0 0.0 7.1e-30 103.7 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KFM00319.1 - 1.9e-05 24.4 0.0 2.5e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain 14-3-3 PF00244.15 KFM00319.1 - 0.088 11.8 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 14-3-3 protein Adaptin_N PF01602.15 KFM00320.1 - 0.00082 17.8 0.3 0.00091 17.6 0.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region DUF721 PF05258.7 KFM00320.1 - 0.0099 16.0 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF721) V-set PF07686.12 KFM00321.1 - 1.3e-06 28.2 0.1 1.3e-06 28.2 0.1 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 KFM00321.1 - 0.00013 21.7 0.0 0.00013 21.7 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 KFM00321.1 - 0.00015 21.8 0.0 0.00019 21.4 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain V-set_CD47 PF08204.6 KFM00321.1 - 0.0039 16.9 0.0 0.0044 16.7 0.0 1.0 1 0 0 1 1 1 1 CD47 immunoglobulin-like domain Ig_3 PF13927.1 KFM00321.1 - 0.0083 16.6 0.0 0.011 16.2 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 KFM00321.1 - 0.027 14.5 0.0 0.028 14.5 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain Herpes_gI PF01688.12 KFM00321.1 - 0.12 11.5 0.0 0.16 11.1 0.0 1.3 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein I fn3 PF00041.16 KFM00322.1 - 1.2e-09 38.1 2.5 0.048 13.7 0.1 4.5 3 2 1 4 4 4 3 Fibronectin type III domain IL6Ra-bind PF09240.5 KFM00322.1 - 4.8e-08 33.0 0.1 1.2e-07 31.7 0.1 1.6 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding EpoR_lig-bind PF09067.5 KFM00322.1 - 0.00015 21.7 0.5 0.00029 20.7 0.0 1.7 2 0 0 2 2 2 1 Erythropoietin receptor, ligand binding Tissue_fac PF01108.12 KFM00322.1 - 0.0006 19.5 4.8 1.4 8.6 0.0 3.4 2 1 1 3 3 3 2 Tissue factor IL4Ra_N PF09238.5 KFM00322.1 - 0.002 18.1 0.2 0.042 13.9 0.1 2.6 2 1 1 3 3 3 1 Interleukin-4 receptor alpha chain, N-terminal PRESAN PF09687.5 KFM00323.1 - 0.07 13.1 1.2 0.08 13.0 0.8 1.1 1 0 0 1 1 1 0 Plasmodium RESA N-terminal 7tm_4 PF13853.1 KFM00325.1 - 8.4e-44 148.8 12.7 8.4e-44 148.8 8.8 2.2 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFM00325.1 - 2.4e-32 112.0 23.0 3.2e-32 111.6 15.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Trypsin PF00089.21 KFM00326.1 - 3.6e-70 235.9 1.6 4e-70 235.8 1.1 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 KFM00326.1 - 4.7e-05 22.7 0.5 0.00012 21.4 0.1 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 KFM00326.1 - 8.4e-05 22.5 0.0 0.00014 21.8 0.0 1.4 1 1 0 1 1 1 1 Trypsin-like peptidase domain A2M_recep PF07677.9 KFM00328.1 - 1.9e-05 24.7 0.4 4.4e-05 23.5 0.1 1.8 2 0 0 2 2 2 1 A-macroglobulin receptor Histone PF00125.19 KFM00330.1 - 4.3e-16 58.7 0.1 6.2e-16 58.2 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFM00330.1 - 0.00019 21.4 0.1 0.00041 20.3 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 7tm_4 PF13853.1 KFM00331.1 - 3.6e-45 153.2 9.9 3.6e-45 153.2 6.9 2.9 2 1 1 3 3 3 1 Olfactory receptor 7tm_1 PF00001.16 KFM00331.1 - 1.2e-30 106.5 19.2 1.7e-30 106.0 13.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.16 KFM00332.1 - 1.3e-50 172.0 17.6 1.9e-50 171.4 12.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM00332.1 - 1.6e-12 47.1 16.9 2.4e-12 46.5 11.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM00332.1 - 2.4e-05 23.5 11.0 2.4e-05 23.5 7.6 1.9 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx Flavi_NS4B PF01349.12 KFM00332.1 - 0.0025 16.7 0.1 0.0049 15.8 0.1 1.4 1 0 0 1 1 1 1 Flavivirus non-structural protein NS4B Sushi PF00084.15 KFM00333.1 - 8.1e-36 122.1 13.4 1.5e-12 47.6 0.9 3.1 3 0 0 3 3 3 3 Sushi domain (SCR repeat) HRM PF02793.17 KFM00333.1 - 0.0011 18.9 10.6 0.0098 15.8 0.4 3.4 2 1 1 3 3 3 2 Hormone receptor domain cEGF PF12662.2 KFM00333.1 - 0.52 9.9 11.7 12 5.6 0.1 3.9 4 0 0 4 4 4 0 Complement Clr-like EGF-like Sushi PF00084.15 KFM00334.1 - 3.2e-16 59.3 6.5 4.7e-11 42.8 1.4 2.0 2 0 0 2 2 2 2 Sushi domain (SCR repeat) Bul1_N PF04425.7 KFM00334.1 - 0.12 10.8 0.1 0.13 10.7 0.1 1.0 1 0 0 1 1 1 0 Bul1 N terminus 7tm_4 PF13853.1 KFM00335.1 - 1.9e-39 134.7 21.9 1.9e-39 134.7 15.2 2.5 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFM00335.1 - 3.6e-28 98.4 27.1 5.1e-28 97.9 18.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 KFM00336.1 - 2.6e-43 147.2 9.4 2.6e-43 147.2 6.5 1.7 2 0 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFM00336.1 - 5.4e-28 97.8 15.7 6.6e-28 97.5 10.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM00336.1 - 0.34 10.0 14.3 0.66 9.0 9.9 1.5 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.1 KFM00337.1 - 2.7e-37 127.7 11.7 2.7e-37 127.7 8.1 1.9 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFM00337.1 - 2.6e-30 105.4 14.2 3.2e-30 105.1 9.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM00337.1 - 1.9e-05 24.0 12.4 3.9e-05 22.9 8.6 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx SBP56 PF05694.6 KFM00338.1 - 5.5e-111 371.2 0.0 6.2e-111 371.1 0.0 1.0 1 0 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.4 KFM00338.1 - 0.00015 20.9 0.0 0.0027 16.8 0.0 2.0 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller DUF1958 PF09211.5 KFM00338.1 - 0.096 12.7 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1958) RVT_1 PF00078.22 KFM00339.1 - 2.6e-20 72.7 0.0 3.7e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 KFM00339.1 - 0.13 11.2 0.1 0.13 11.2 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) PT PF04886.7 KFM00341.1 - 0.00025 20.2 81.0 0.13 11.6 12.1 4.2 1 1 2 3 3 3 2 PT repeat Glyco_transf_49 PF13896.1 KFM00342.1 - 1.2e-50 172.4 0.0 1.3e-50 172.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan DUF490 PF04357.8 KFM00343.1 - 8e-09 35.0 14.0 0.092 11.8 0.0 8.1 3 3 3 8 8 8 5 Family of unknown function (DUF490) DUF2993 PF11209.3 KFM00343.1 - 0.0083 16.0 4.5 64 3.3 0.2 7.8 2 2 3 6 6 6 0 Protein of unknown function (DUF2993) Phage_30_3 PF08010.6 KFM00343.1 - 0.11 11.9 0.0 61 3.0 0.0 4.8 7 0 0 7 7 7 0 Bacteriophage protein GP30.3 DNA_pol3_alpha PF07733.7 KFM00343.1 - 0.58 8.5 1.3 65 1.7 0.0 4.3 5 0 0 5 5 5 0 Bacterial DNA polymerase III alpha subunit DUF945 PF06097.6 KFM00344.1 - 1.3e-09 37.4 0.0 1.2 7.8 0.0 6.8 4 1 1 6 6 6 6 Bacterial protein of unknown function (DUF945) DNA_pol3_alpha PF07733.7 KFM00344.1 - 1.7 7.0 4.0 43 2.3 0.0 4.3 7 0 0 7 7 7 0 Bacterial DNA polymerase III alpha subunit PDZ PF00595.19 KFM00345.1 - 4e-08 33.3 0.2 5.1e-07 29.7 0.1 2.0 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM00345.1 - 7e-07 29.0 0.8 1.3e-06 28.1 0.5 1.5 1 1 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.9 KFM00345.1 - 0.02 14.8 0.1 0.055 13.4 0.0 1.7 1 1 0 1 1 1 0 GRASP55/65 PDZ-like domain C1-set PF07654.10 KFM00346.1 - 2.2e-22 78.8 0.0 3.7e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.1 KFM00346.1 - 1.5e-05 25.3 0.3 2.3e-05 24.7 0.2 1.2 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.7 KFM00346.1 - 0.0001 22.1 0.0 0.00016 21.5 0.0 1.2 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.1 KFM00346.1 - 0.001 19.1 0.0 0.0016 18.5 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain MHC_II_beta PF00969.14 KFM00346.1 - 0.021 14.7 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 Class II histocompatibility antigen, beta domain ig PF00047.20 KFM00346.1 - 0.08 13.0 0.4 0.4 10.8 0.3 2.1 1 1 1 2 2 2 0 Immunoglobulin domain I-set PF07679.11 KFM00346.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin I-set domain C1-set PF07654.10 KFM00347.1 - 2.1e-22 78.8 0.0 3.4e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.1 KFM00347.1 - 0.0012 19.3 0.2 0.0027 18.1 0.1 1.6 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 KFM00347.1 - 0.0017 18.3 0.0 0.0029 17.6 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.7 KFM00347.1 - 0.0021 17.9 0.1 0.0071 16.2 0.1 1.8 1 1 0 1 1 1 1 CD80-like C2-set immunoglobulin domain MHC_II_beta PF00969.14 KFM00347.1 - 0.0053 16.7 0.0 0.0077 16.1 0.0 1.2 1 0 0 1 1 1 1 Class II histocompatibility antigen, beta domain ig PF00047.20 KFM00347.1 - 0.1 12.7 0.0 1.3 9.2 0.0 2.4 3 0 0 3 3 3 0 Immunoglobulin domain ABC_tran PF00005.22 KFM00348.1 - 5e-31 107.8 0.0 6.3e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 KFM00348.1 - 2.7e-06 26.7 0.0 0.0038 16.4 0.0 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KFM00348.1 - 0.00077 19.5 0.0 0.56 10.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KFM00348.1 - 0.00093 18.6 0.1 0.32 10.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KFM00348.1 - 0.0024 17.3 0.0 0.0054 16.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KFM00348.1 - 0.0097 16.0 0.3 0.32 11.1 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KFM00348.1 - 0.027 14.0 0.1 6.5 6.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KFM00348.1 - 0.029 14.7 0.0 0.043 14.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 KFM00348.1 - 0.039 13.6 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase SbcCD_C PF13558.1 KFM00348.1 - 0.051 13.4 0.3 0.45 10.4 0.2 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 KFM00348.1 - 0.054 13.4 1.3 0.15 12.0 0.9 1.7 1 1 0 1 1 1 0 AAA ATPase domain ABC_membrane PF00664.18 KFM00350.1 - 3.2e-31 108.7 0.0 3.8e-31 108.5 0.0 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region BMC PF00936.14 KFM00350.1 - 0.11 12.1 2.1 0.12 12.0 0.1 2.0 2 0 0 2 2 2 0 BMC domain AAA_16 PF13191.1 KFM00352.1 - 1e-10 41.9 0.0 2.6e-10 40.6 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFM00352.1 - 1.2e-07 31.9 0.0 3.3e-07 30.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KFM00352.1 - 3.3e-07 30.5 0.0 0.014 15.5 0.0 2.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KFM00352.1 - 0.00016 21.3 0.1 0.00031 20.4 0.1 1.5 1 1 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 KFM00352.1 - 0.00047 19.8 0.1 0.0041 16.8 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain DUF2075 PF09848.4 KFM00352.1 - 0.0091 15.0 0.0 0.013 14.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 KFM00352.1 - 0.032 13.7 0.0 7.6 5.9 0.0 2.1 2 0 0 2 2 2 0 DEAD/DEAH box helicase PIF1 PF05970.9 KFM00352.1 - 0.11 11.4 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Sigma54_activ_2 PF14532.1 KFM00352.1 - 0.12 12.3 0.1 16 5.5 0.0 2.3 1 1 1 2 2 2 0 Sigma-54 interaction domain Viral_helicase1 PF01443.13 KFM00352.1 - 0.16 11.4 0.1 0.24 10.8 0.1 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Btz PF09405.5 KFM00353.1 - 7.1e-26 90.7 6.0 7.1e-26 90.7 4.2 3.0 2 1 1 3 3 3 1 CASC3/Barentsz eIF4AIII binding PEHE PF15275.1 KFM00354.1 - 6.7e-29 100.8 0.4 6.7e-29 100.8 0.3 2.2 3 0 0 3 3 3 1 PEHE domain tRNA-synt_1c PF00749.16 KFM00354.1 - 0.11 11.1 0.1 0.17 10.4 0.1 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain zf-C4 PF00105.13 KFM00355.1 - 1.7e-32 111.4 14.3 1.9e-32 111.2 9.9 1.0 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) PAN_3 PF08277.7 KFM00355.1 - 0.015 14.9 1.8 0.023 14.2 1.2 1.3 1 0 0 1 1 1 0 PAN-like domain ISAV_HA PF06215.6 KFM00355.1 - 0.017 13.4 1.5 0.019 13.2 1.1 1.0 1 0 0 1 1 1 0 Infectious salmon anaemia virus haemagglutinin DUF164 PF02591.10 KFM00355.1 - 0.045 13.5 2.3 0.045 13.5 1.6 2.5 1 1 1 2 2 2 0 Putative zinc ribbon domain Fer4_6 PF12837.2 KFM00355.1 - 0.051 13.4 0.7 0.051 13.4 0.5 3.1 4 0 0 4 4 4 0 4Fe-4S binding domain Med24_N PF11277.3 KFM00356.1 - 0 1494.4 17.3 0 1494.3 12.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 24 N-terminal IL6 PF00489.12 KFM00357.1 - 6e-42 142.8 0.1 6.7e-42 142.6 0.1 1.0 1 0 0 1 1 1 1 Interleukin-6/G-CSF/MGF family HTH_34 PF13601.1 KFM00357.1 - 0.074 13.0 0.1 6.5 6.8 0.1 2.1 1 1 1 2 2 2 0 Winged helix DNA-binding domain Gasdermin PF04598.7 KFM00358.1 - 1.7e-08 33.6 3.2 2.1e-08 33.3 2.2 1.0 1 0 0 1 1 1 1 Gasdermin family DUF3554 PF12074.3 KFM00358.1 - 0.022 14.1 0.3 0.025 14.0 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3554) DUF3396 PF11876.3 KFM00358.1 - 0.022 13.8 0.1 0.024 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3396) ORMDL PF04061.9 KFM00359.1 - 7.9e-53 177.6 4.6 8.9e-53 177.4 3.2 1.0 1 0 0 1 1 1 1 ORMDL family 7tm_3 PF00003.17 KFM00359.1 - 0.036 13.3 2.8 0.078 12.3 1.9 1.7 1 1 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR LRR_8 PF13855.1 KFM00360.1 - 1.1e-23 82.7 7.2 2.8e-09 36.5 1.0 3.0 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 KFM00360.1 - 2.6e-08 32.7 8.2 0.012 15.4 0.3 5.6 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_4 PF12799.2 KFM00360.1 - 2.8e-06 26.8 5.2 0.0023 17.4 0.6 3.8 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) DUF3700 PF12481.3 KFM00360.1 - 2.2e-05 23.7 0.0 5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Aluminium induced protein LRRNT PF01462.13 KFM00360.1 - 0.012 15.0 1.3 0.016 14.6 0.0 2.0 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain LRR_7 PF13504.1 KFM00360.1 - 0.014 15.5 8.9 3.3 8.3 0.1 5.5 5 1 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 KFM00360.1 - 0.025 14.6 4.0 6.4 7.1 0.2 4.0 2 1 1 3 3 3 0 Leucine Rich repeat Sp38 PF07354.7 KFM00361.1 - 1.2e-121 404.4 8.6 1.5e-121 404.2 6.0 1.1 1 0 0 1 1 1 1 Zona-pellucida-binding protein (Sp38) zf-H2C2_2 PF13465.1 KFM00362.1 - 4.9e-25 86.5 31.8 1.8e-07 31.1 0.6 6.3 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.21 KFM00362.1 - 3.6e-15 55.2 41.8 2.1e-05 24.5 0.3 6.8 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM00362.1 - 5.5e-09 35.7 40.3 0.0005 20.2 0.2 6.6 6 0 0 6 6 6 4 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KFM00362.1 - 0.073 13.3 33.7 0.26 11.5 1.8 6.3 6 0 0 6 6 6 0 C2H2-type zinc-finger domain GAGA PF09237.6 KFM00362.1 - 0.11 12.0 0.1 0.11 12.0 0.1 2.8 2 1 0 3 3 3 0 GAGA factor C1_1 PF00130.17 KFM00362.1 - 0.57 9.9 23.7 0.6 9.8 1.2 3.8 2 1 2 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_6 PF13912.1 KFM00362.1 - 2.5 8.1 38.6 1.2 9.1 1.0 6.8 6 2 0 6 6 6 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM00362.1 - 5.7 7.2 31.1 0.35 11.0 0.2 6.2 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding adh_short PF00106.20 KFM00363.1 - 1.8e-12 47.4 0.0 2.5e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFM00363.1 - 0.00048 19.9 0.0 0.00057 19.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFM00363.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 KR domain BPS PF08947.5 KFM00364.1 - 4.8e-06 26.1 0.5 7.1e-06 25.5 0.3 1.3 1 0 0 1 1 1 1 BPS (Between PH and SH2) DUF4083 PF13314.1 KFM00365.1 - 0.058 13.2 1.0 10 6.0 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4083) BORG_CEP PF14957.1 KFM00366.1 - 5.1e-24 85.5 0.0 1.1e-23 84.4 0.0 1.6 1 1 0 1 1 1 1 Cdc42 effector PBD PF00786.23 KFM00366.1 - 1.9e-09 37.8 0.2 4e-09 36.7 0.1 1.7 1 1 0 1 1 1 1 P21-Rho-binding domain PHD PF00628.24 KFM00367.1 - 1.1e-07 31.4 10.2 1.1e-07 31.4 7.1 1.8 1 1 1 2 2 2 1 PHD-finger 7tm_4 PF13853.1 KFM00368.1 - 9.2e-43 145.4 15.5 9.2e-43 145.4 10.7 2.9 3 0 0 3 3 3 1 Olfactory receptor 7tm_1 PF00001.16 KFM00368.1 - 5.4e-33 114.2 25.7 7.8e-33 113.6 17.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Gag_p30 PF02093.11 KFM00369.1 - 6.4e-21 74.5 0.1 7.4e-21 74.3 0.1 1.0 1 0 0 1 1 1 1 Gag P30 core shell protein BAAT_C PF08840.6 KFM00370.1 - 2.9e-28 99.0 0.0 3.4e-28 98.7 0.0 1.0 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_5 PF12695.2 KFM00370.1 - 9.4e-05 22.1 0.0 0.00014 21.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFM00370.1 - 0.00096 19.0 0.2 0.0021 17.9 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 KFM00370.1 - 0.0022 17.4 0.0 0.0076 15.7 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.13 KFM00370.1 - 0.04 13.2 0.2 0.91 8.7 0.2 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family WD40 PF00400.27 KFM00371.1 - 1.8e-40 135.4 9.4 1.9e-11 43.3 0.0 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat Prp19 PF08606.6 KFM00371.1 - 1e-32 111.6 1.9 1e-32 111.6 1.3 1.8 2 0 0 2 2 2 1 Prp19/Pso4-like Nup160 PF11715.3 KFM00371.1 - 1.2e-05 23.7 0.3 0.0049 15.0 0.0 3.0 1 1 1 3 3 3 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KFM00371.1 - 0.00037 18.9 0.0 0.54 8.4 0.0 2.5 3 0 0 3 3 3 2 Cytochrome D1 heme domain eIF2A PF08662.6 KFM00371.1 - 0.00043 20.0 0.0 0.57 9.8 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 KFM00371.1 - 0.053 12.2 0.3 0.25 10.0 0.2 2.0 1 1 0 1 1 1 0 Nup133 N terminal like DUF1830 PF08865.6 KFM00371.1 - 0.066 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1830) DUF1019 PF06254.6 KFM00371.1 - 0.14 12.2 0.3 1.4 9.1 0.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1019) PTR2 PF00854.16 KFM00372.1 - 2.9e-49 167.8 8.1 3.1e-31 108.4 0.7 2.1 2 0 0 2 2 2 2 POT family MFS_1 PF07690.11 KFM00372.1 - 3.3e-07 29.3 35.2 0.00064 18.5 13.5 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily SRCR PF00530.13 KFM00373.1 - 8.2e-25 87.0 3.7 1.3e-14 54.2 0.2 2.1 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 KFM00373.1 - 0.0061 16.7 0.1 0.0061 16.7 0.1 1.9 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain Mod_r PF07200.8 KFM00374.1 - 4e-41 140.4 19.1 4.7e-41 140.1 13.2 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein MSG PF02349.10 KFM00374.1 - 0.048 13.6 1.8 0.11 12.5 1.3 1.6 1 0 0 1 1 1 0 Major surface glycoprotein T2SM PF04612.7 KFM00374.1 - 0.082 12.7 8.8 1.3 8.7 2.5 2.4 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M DltD_M PF04918.7 KFM00374.1 - 1.4 9.0 8.7 0.37 10.9 1.2 2.1 1 1 1 2 2 2 0 DltD central region Asp PF00026.18 KFM00375.1 - 2.3e-82 276.7 5.5 2.7e-82 276.5 3.8 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KFM00375.1 - 2.2e-14 53.7 0.3 4e-14 52.9 0.2 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal A1_Propeptide PF07966.7 KFM00375.1 - 1.7e-06 27.5 0.7 2.9e-06 26.8 0.5 1.4 1 0 0 1 1 1 1 A1 Propeptide Asp_protease_2 PF13650.1 KFM00375.1 - 0.0028 18.1 0.1 0.26 11.8 0.0 2.8 2 1 0 2 2 2 1 Aspartyl protease FXa_inhibition PF14670.1 KFM00376.1 - 6.6e-15 54.9 28.1 4.6e-09 36.2 3.8 3.3 3 0 0 3 3 3 2 Coagulation Factor Xa inhibitory site EGF_CA PF07645.10 KFM00376.1 - 4.7e-14 52.0 17.1 5.1e-09 35.9 2.7 3.2 3 1 0 3 3 3 2 Calcium-binding EGF domain cEGF PF12662.2 KFM00376.1 - 3e-09 36.3 11.2 2.4e-06 27.0 0.3 4.1 4 0 0 4 4 4 2 Complement Clr-like EGF-like EGF_3 PF12947.2 KFM00376.1 - 7.8e-06 25.7 15.3 0.00043 20.1 0.6 3.7 1 1 2 3 3 3 2 EGF domain EGF PF00008.22 KFM00376.1 - 0.0038 17.1 5.5 0.0038 17.1 3.8 3.6 2 1 1 3 3 3 2 EGF-like domain MMS1_N PF10433.4 KFM00377.1 - 2.8e-94 316.0 0.1 9.6e-94 314.2 0.0 1.9 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 KFM00377.1 - 2.3e-84 283.2 0.4 2.2e-83 279.9 0.1 2.6 3 0 0 3 3 3 1 CPSF A subunit region Beta_propel PF09826.4 KFM00377.1 - 0.069 11.4 0.0 0.11 10.7 0.0 1.3 1 0 0 1 1 1 0 Beta propeller domain Cytochrom_B561 PF03188.11 KFM00378.1 - 1.4e-09 37.8 4.6 1.9e-07 31.0 0.1 2.9 3 1 1 4 4 4 2 Eukaryotic cytochrome b561 NnrS PF05940.7 KFM00378.1 - 0.13 11.1 17.5 0.23 10.3 12.1 1.6 1 1 0 1 1 1 0 NnrS protein V_ATPase_I PF01496.14 KFM00378.1 - 0.37 8.5 2.3 0.58 7.9 0.3 1.8 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF2628 PF10947.3 KFM00378.1 - 5.3 6.8 8.8 13 5.6 6.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2628) TMEM138 PF14935.1 KFM00379.1 - 5.8e-21 75.0 13.2 5.8e-21 75.0 9.1 1.4 2 0 0 2 2 2 1 Transmembrane protein 138 Transmemb_17 PF09799.4 KFM00380.1 - 9.8e-17 61.2 1.2 1.2e-16 60.9 0.9 1.1 1 0 0 1 1 1 1 Predicted membrane protein PMP22_Claudin PF00822.15 KFM00381.1 - 1.5e-10 40.9 0.0 1.7e-10 40.8 0.0 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFM00381.1 - 1.2e-07 31.5 0.0 1.4e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Band_7 PF01145.20 KFM00382.1 - 9.1e-07 28.9 1.6 9.1e-07 28.9 1.1 2.0 1 1 0 2 2 2 1 SPFH domain / Band 7 family DUF4346 PF14251.1 KFM00382.1 - 0.042 13.5 1.3 0.087 12.5 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4346) Ala_racemase_N PF01168.15 KFM00383.1 - 2.7e-39 134.9 0.0 3.4e-39 134.6 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain TFIIB PF00382.14 KFM00384.1 - 1.2e-06 28.2 0.0 0.015 15.0 0.0 2.7 2 1 0 2 2 2 2 Transcription factor TFIIB repeat RBD-FIP PF09457.5 KFM00385.1 - 2.8e-21 75.0 3.9 7.8e-21 73.6 2.7 1.8 1 0 0 1 1 1 1 FIP domain Nucleoplasmin PF03066.10 KFM00386.1 - 4e-15 55.6 0.1 4.1e-15 55.5 0.1 1.0 1 0 0 1 1 1 1 Nucleoplasmin eIF_4EBP PF05456.6 KFM00387.1 - 3.1e-21 75.2 0.0 3.5e-21 75.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) TGF_beta PF00019.15 KFM00388.1 - 4.6e-29 100.7 0.9 7.8e-29 100.0 0.6 1.4 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.13 KFM00388.1 - 1.5e-15 57.1 0.1 3.3e-15 56.0 0.1 1.5 1 0 0 1 1 1 1 TGF-beta propeptide SPRY PF00622.23 KFM00389.1 - 1.6e-13 50.8 0.5 2.4e-08 34.1 0.0 2.4 2 0 0 2 2 2 2 SPRY domain START PF01852.14 KFM00390.1 - 1.6e-44 151.6 0.0 2e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 START domain Polyketide_cyc PF03364.15 KFM00390.1 - 0.0012 18.8 0.0 0.0063 16.4 0.0 2.2 2 1 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 KFM00390.1 - 0.089 12.9 0.1 0.22 11.6 0.0 1.9 2 2 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport LSM PF01423.17 KFM00391.1 - 0.0013 18.1 0.1 0.0029 17.1 0.0 1.6 1 0 0 1 1 1 1 LSM domain DDHD PF02862.12 KFM00393.1 - 2.3e-52 178.0 0.0 5.7e-52 176.7 0.0 1.7 2 0 0 2 2 2 1 DDHD domain WWE PF02825.15 KFM00393.1 - 2.1e-13 49.4 4.0 1e-08 34.4 0.1 3.0 2 1 1 3 3 3 2 WWE domain SAM_1 PF00536.25 KFM00393.1 - 8.2e-13 48.3 0.0 1.7e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFM00393.1 - 2.5e-05 24.0 0.0 5.7e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.5 KFM00393.1 - 0.011 15.6 0.0 0.037 13.9 0.1 1.8 2 0 0 2 2 2 0 IGR protein motif DUF676 PF05057.9 KFM00393.1 - 0.16 11.2 0.1 5.8 6.1 0.1 2.3 1 1 0 1 1 1 0 Putative serine esterase (DUF676) PAP2 PF01569.16 KFM00394.1 - 1.1e-27 96.2 2.6 7e-27 93.6 1.0 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 KFM00394.1 - 0.035 14.3 0.1 0.083 13.1 0.1 1.6 1 0 0 1 1 1 0 PAP2 superfamily C-terminal Virul_fac_BrkB PF03631.10 KFM00394.1 - 0.093 12.0 2.9 1.5 8.1 0.5 2.1 2 0 0 2 2 2 0 Virulence factor BrkB YhhN PF07947.9 KFM00394.1 - 0.11 11.8 4.3 1.6 8.0 3.0 2.5 1 1 1 2 2 2 0 YhhN-like protein EmrE PF13536.1 KFM00394.1 - 0.22 11.7 5.7 3.4 7.9 0.1 2.7 2 1 1 3 3 3 0 Multidrug resistance efflux transporter PWWP PF00855.12 KFM00395.1 - 4.5e-38 129.3 15.9 1.1e-22 79.9 1.4 3.4 3 0 0 3 3 3 2 PWWP domain SET PF00856.23 KFM00395.1 - 1.3e-24 87.3 0.4 1.3e-24 87.3 0.3 4.7 4 2 0 4 4 4 1 SET domain PHD PF00628.24 KFM00395.1 - 1.8e-13 49.9 75.0 6e-07 29.0 7.3 6.5 4 2 2 6 6 6 4 PHD-finger zf-HC5HC2H_2 PF13832.1 KFM00395.1 - 0.0016 18.4 2.9 0.0016 18.4 2.0 6.3 3 2 2 5 5 5 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KFM00395.1 - 0.0043 17.1 13.1 0.0043 17.1 9.1 6.2 3 2 2 5 5 5 3 PHD-like zinc-binding domain LETM1 PF07766.8 KFM00396.1 - 4.7e-106 353.7 6.9 6.1e-106 353.3 4.8 1.1 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.22 KFM00396.1 - 0.0074 15.7 2.6 0.036 13.5 0.2 3.2 2 1 1 3 3 3 1 SAP domain Pkinase_Tyr PF07714.12 KFM00397.1 - 3e-99 331.3 0.0 4.3e-99 330.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM00397.1 - 2.9e-46 157.7 0.0 4.4e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain I-set PF07679.11 KFM00397.1 - 2.4e-38 129.8 0.0 6e-14 51.6 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM00397.1 - 2.1e-29 101.4 0.2 1.7e-09 37.6 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.20 KFM00397.1 - 6.8e-23 80.5 1.5 1.7e-06 28.0 0.0 4.4 3 1 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 KFM00397.1 - 1.4e-17 63.8 0.1 8.8e-06 26.1 0.0 4.3 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 KFM00397.1 - 4.6e-12 45.8 2.1 0.0006 19.6 0.0 4.9 3 3 0 3 3 3 3 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM00397.1 - 0.00013 21.7 0.3 0.24 11.3 0.0 3.8 2 1 2 4 4 4 1 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.11 KFM00397.1 - 0.028 12.7 3.8 8.4 4.5 0.0 3.1 2 1 0 2 2 2 0 Alphaherpesvirus glycoprotein E V-set_CD47 PF08204.6 KFM00397.1 - 0.068 12.9 0.2 0.93 9.2 0.0 2.8 3 0 0 3 3 3 0 CD47 immunoglobulin-like domain TACC PF05010.9 KFM00398.1 - 4.8e-79 264.9 32.9 6.8e-79 264.4 22.8 1.2 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC) Methyltrn_RNA_4 PF09936.4 KFM00398.1 - 0.78 9.2 9.2 3.7 7.0 1.9 2.2 2 0 0 2 2 2 0 SAM-dependent RNA methyltransferase ADIP PF11559.3 KFM00398.1 - 1.4 8.7 26.4 0.48 10.3 9.0 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF3584 PF12128.3 KFM00398.1 - 2 5.6 26.4 3.3 4.9 18.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HAUS-augmin3 PF14932.1 KFM00398.1 - 5.7 6.0 31.7 1.9 7.6 6.5 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 IncA PF04156.9 KFM00398.1 - 9.3 5.7 33.6 2 7.9 8.2 3.1 1 1 2 3 3 3 0 IncA protein PH PF00169.24 KFM00399.1 - 2.3e-29 101.6 0.3 8.9e-16 57.9 0.1 2.3 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 KFM00399.1 - 5.1e-16 58.9 0.6 6.3e-07 29.6 0.7 4.0 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 KFM00399.1 - 1e-09 38.2 1.4 0.00073 19.5 0.1 3.4 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.1 KFM00399.1 - 8.3e-09 35.6 0.1 0.005 16.9 0.0 2.9 2 1 0 2 2 2 2 Pleckstrin homology domain Mcp5_PH PF12814.2 KFM00399.1 - 2.5e-05 24.1 0.0 0.0027 17.6 0.0 2.4 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology Reprolysin PF01421.14 KFM00400.1 - 4.3e-66 222.2 0.0 8.8e-66 221.2 0.0 1.5 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.7 KFM00400.1 - 6.2e-38 129.4 5.6 6.2e-38 129.4 3.9 3.6 4 2 0 4 4 1 1 ADAM cysteine-rich Pep_M12B_propep PF01562.14 KFM00400.1 - 9.9e-26 90.0 0.2 1.8e-25 89.2 0.1 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide Disintegrin PF00200.18 KFM00400.1 - 1.5e-22 79.5 28.8 1.5e-22 79.5 20.0 4.6 3 1 2 5 5 5 1 Disintegrin Reprolysin_5 PF13688.1 KFM00400.1 - 9.1e-22 77.9 0.2 3e-21 76.2 0.1 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KFM00400.1 - 1.4e-19 70.8 0.1 3e-19 69.7 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFM00400.1 - 9.6e-14 51.8 0.7 2.1e-13 50.6 0.5 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFM00400.1 - 3.9e-13 49.4 0.1 6.8e-13 48.6 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like EGF_2 PF07974.8 KFM00400.1 - 0.00041 20.4 11.2 0.00041 20.4 7.8 6.9 5 2 2 7 7 6 1 EGF-like domain Peptidase_M10 PF00413.19 KFM00400.1 - 0.0076 15.9 0.1 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.4 KFM00400.1 - 0.014 14.2 0.5 0.025 13.4 0.4 1.3 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M57 PF12388.3 KFM00400.1 - 0.016 14.5 0.7 0.029 13.7 0.5 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M43 PF05572.8 KFM00400.1 - 0.04 13.5 0.1 0.04 13.5 0.1 2.1 2 0 0 2 2 2 0 Pregnancy-associated plasma protein-A Reprolysin PF01421.14 KFM00401.1 - 5.8e-38 130.4 9.5 4.1e-33 114.6 0.0 2.7 3 0 0 3 3 3 2 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.7 KFM00401.1 - 1.3e-30 105.8 5.7 1.3e-30 105.8 4.0 2.3 2 0 0 2 2 2 1 ADAM cysteine-rich Pep_M12B_propep PF01562.14 KFM00401.1 - 5.2e-18 65.1 0.1 8.1e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 Reprolysin family propeptide Disintegrin PF00200.18 KFM00401.1 - 1.8e-15 56.9 22.6 1.8e-15 56.9 15.7 2.7 3 0 0 3 3 3 1 Disintegrin Reprolysin_5 PF13688.1 KFM00401.1 - 1.9e-10 41.0 0.0 3.1e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KFM00401.1 - 5e-06 26.1 0.2 1.1e-05 25.0 0.0 1.6 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KFM00401.1 - 8.7e-06 26.2 0.0 1.6e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like IDO PF01231.13 KFM00402.1 - 2.6e-131 437.9 0.0 2.9e-131 437.7 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase TC1 PF15063.1 KFM00403.1 - 6e-39 131.4 0.2 7.4e-39 131.1 0.1 1.1 1 0 0 1 1 1 1 Thyroid cancer protein 1 Toprim_4 PF13662.1 KFM00403.1 - 0.035 14.1 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 Toprim domain MgtE_N PF03448.12 KFM00403.1 - 0.052 13.8 1.5 0.43 10.9 1.0 1.9 1 1 0 1 1 1 0 MgtE intracellular N domain Spore_III_AB PF09548.5 KFM00403.1 - 0.059 13.1 0.3 0.073 12.8 0.2 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) zf-met PF12874.2 KFM00404.1 - 2.2e-29 100.6 25.8 8.5e-08 32.1 1.5 4.3 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFM00404.1 - 2.5e-25 87.9 20.5 7.6e-08 32.2 0.5 4.3 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.7 KFM00404.1 - 1.3e-07 30.9 18.0 0.0023 17.4 0.3 4.2 4 0 0 4 4 4 3 U1 zinc finger zf-C2H2_2 PF12756.2 KFM00404.1 - 7.9e-07 29.1 17.2 0.037 14.1 0.3 4.1 2 1 1 4 4 4 4 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 KFM00404.1 - 5e-06 26.4 17.3 0.38 11.2 0.2 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger DUF3449 PF11931.3 KFM00404.1 - 0.046 13.2 10.2 0.049 13.1 0.2 3.5 3 1 0 4 4 4 0 Domain of unknown function (DUF3449) zf-H2C2_2 PF13465.1 KFM00404.1 - 1.2 9.5 9.4 20 5.7 0.5 4.2 4 0 0 4 4 4 0 Zinc-finger double domain zf-DBF PF07535.7 KFM00404.1 - 1.8 8.2 13.0 5.6 6.7 0.3 3.8 4 0 0 4 4 4 0 DBF zinc finger zf-C2H2 PF00096.21 KFM00404.1 - 6.2 7.3 14.5 1.9 9.0 0.4 4.0 4 0 0 4 4 4 0 Zinc finger, C2H2 type Fz PF01392.17 KFM00405.1 - 7.8e-32 110.0 3.0 7.8e-32 110.0 2.1 2.1 2 1 1 3 3 3 1 Fz domain NTR PF01759.16 KFM00405.1 - 1.1e-17 63.5 0.5 1.8e-17 62.9 0.4 1.3 1 0 0 1 1 1 1 UNC-6/NTR/C345C module NinG PF05766.7 KFM00405.1 - 0.041 13.6 0.2 0.074 12.7 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein DUF555 PF04475.7 KFM00405.1 - 0.062 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF555) Erf4 PF10256.4 KFM00406.1 - 1.4e-21 76.5 0.0 1.5e-21 76.4 0.0 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF3920 PF13058.1 KFM00406.1 - 0.071 12.9 0.1 0.099 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3920) Sld5 PF05916.6 KFM00407.1 - 6.6e-06 26.3 0.2 1.2e-05 25.5 0.2 1.6 1 0 0 1 1 1 1 GINS complex protein CBM_21 PF03370.8 KFM00408.1 - 3.7e-34 117.1 0.2 5.1e-34 116.6 0.1 1.2 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit CBM_25 PF03423.8 KFM00408.1 - 0.00019 21.4 0.0 0.00038 20.4 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate binding domain (family 25) Acyltransferase PF01553.16 KFM00409.1 - 1.3e-18 66.6 0.1 2.6e-18 65.7 0.1 1.5 1 0 0 1 1 1 1 Acyltransferase FTCD_N PF07837.7 KFM00409.1 - 0.084 12.3 0.0 0.27 10.7 0.0 1.7 2 0 0 2 2 2 0 Formiminotransferase domain, N-terminal subdomain Homeobox PF00046.24 KFM00410.1 - 4.7e-22 77.3 1.0 7.2e-22 76.7 0.7 1.3 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 KFM00410.1 - 0.11 11.5 0.1 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Ank PF00023.25 KFM00411.1 - 2.8e-194 620.1 67.5 4.3e-10 38.8 0.0 23.5 22 1 1 23 23 23 22 Ankyrin repeat Ank_2 PF12796.2 KFM00411.1 - 7.6e-173 561.4 49.4 9.1e-25 86.8 0.3 11.2 2 2 10 12 12 12 12 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFM00411.1 - 4.6e-143 463.4 52.6 3e-13 49.8 0.2 15.3 7 3 10 17 17 17 17 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM00411.1 - 1.5e-133 421.0 45.4 4e-06 26.5 0.0 23.7 23 0 0 23 23 23 22 Ankyrin repeat Ank_5 PF13857.1 KFM00411.1 - 4.5e-125 404.8 54.5 1.4e-11 44.2 0.0 20.0 3 3 18 21 21 21 20 Ankyrin repeats (many copies) ZU5 PF00791.15 KFM00411.1 - 1.1e-37 127.7 0.3 2.4e-34 117.0 0.0 2.8 2 0 0 2 2 2 2 ZU5 domain Death PF00531.17 KFM00411.1 - 9.8e-18 63.7 0.1 2.5e-17 62.3 0.1 1.8 1 0 0 1 1 1 1 Death domain YfmQ PF10787.4 KFM00411.1 - 0.092 12.1 0.0 31 3.8 0.0 4.8 6 2 1 7 7 7 0 Uncharacterised protein from bacillus cereus group Adap_comp_sub PF00928.16 KFM00412.1 - 2.6e-73 246.3 0.0 3.5e-73 245.9 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KFM00412.1 - 5.9e-07 29.3 0.1 1.2e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Trypsin PF00089.21 KFM00413.1 - 8.8e-69 231.4 0.0 1.4e-68 230.8 0.0 1.3 1 0 0 1 1 1 1 Trypsin Kringle PF00051.13 KFM00413.1 - 7.6e-46 154.1 27.1 7.9e-24 83.5 3.6 3.3 3 0 0 3 3 3 2 Kringle domain EGF PF00008.22 KFM00413.1 - 0.00038 20.3 6.3 0.00038 20.3 4.4 4.0 5 1 0 5 5 5 1 EGF-like domain fn1 PF00039.13 KFM00413.1 - 0.0073 16.0 4.3 0.0073 16.0 3.0 2.8 3 0 0 3 3 3 1 Fibronectin type I domain hEGF PF12661.2 KFM00413.1 - 0.025 14.6 2.9 0.25 11.5 0.2 3.3 2 0 0 2 2 2 0 Human growth factor-like EGF Pkinase PF00069.20 KFM00414.1 - 7.7e-41 139.9 0.0 1.6e-40 138.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM00414.1 - 1.2e-26 93.3 0.0 3.4e-26 91.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase IKKbetaNEMObind PF12179.3 KFM00414.1 - 9e-19 67.0 9.6 9e-19 67.0 6.7 2.6 2 0 0 2 2 2 1 I-kappa-kinase-beta NEMO binding domain ubiquitin PF00240.18 KFM00414.1 - 7.2e-05 22.1 0.2 0.00021 20.6 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin family Kdo PF06293.9 KFM00414.1 - 0.0001 21.4 0.0 0.00024 20.2 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFM00414.1 - 0.00073 19.3 1.0 0.0031 17.3 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KFM00414.1 - 0.0018 17.6 0.0 0.0053 16.1 0.0 1.8 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Snapin_Pallidin PF14712.1 KFM00414.1 - 0.36 11.1 7.7 0.22 11.8 0.1 3.4 2 0 0 2 2 2 0 Snapin/Pallidin zf-C4H2 PF10146.4 KFM00414.1 - 4.5 7.2 7.4 1.4 8.9 0.5 2.7 2 1 1 3 3 3 0 Zinc finger-containing protein Porin_3 PF01459.17 KFM00415.1 - 2.4e-78 263.1 5.6 2.7e-78 263.0 3.9 1.0 1 0 0 1 1 1 1 Eukaryotic porin DNA_pol_B_palm PF14792.1 KFM00416.1 - 1.5e-40 137.7 0.0 2.9e-40 136.8 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.4 KFM00416.1 - 3.5e-22 77.7 0.1 2e-21 75.2 0.0 2.2 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.1 KFM00416.1 - 1e-17 63.5 0.0 1.9e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_5 PF14520.1 KFM00416.1 - 1.9e-08 34.3 0.5 1.2e-06 28.6 0.0 2.6 2 1 0 2 2 2 1 Helix-hairpin-helix domain HHH PF00633.18 KFM00416.1 - 0.0025 17.4 0.3 0.34 10.7 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_8 PF14716.1 KFM00416.1 - 0.005 16.9 0.1 0.43 10.7 0.0 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_2 PF12826.2 KFM00416.1 - 0.0097 15.7 0.0 3.7 7.5 0.0 2.7 1 1 1 2 2 2 2 Helix-hairpin-helix motif HHH_3 PF12836.2 KFM00416.1 - 0.024 14.5 0.7 0.34 10.8 0.0 3.1 3 1 1 4 4 4 0 Helix-hairpin-helix motif Cdd1 PF11731.3 KFM00416.1 - 0.025 14.4 0.0 0.054 13.4 0.0 1.7 1 0 0 1 1 1 0 Pathogenicity locus NTP_transf_2 PF01909.18 KFM00416.1 - 0.068 13.5 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain C2 PF00168.25 KFM00417.1 - 5.6e-17 61.3 0.0 1.9e-09 37.2 0.0 2.3 2 0 0 2 2 2 2 C2 domain SNAPc_SNAP43 PF09808.4 KFM00418.1 - 1.6e-52 177.9 4.6 1.6e-52 177.9 3.2 1.6 2 0 0 2 2 2 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 DUF1681 PF07933.9 KFM00418.1 - 0.049 13.2 0.3 0.59 9.6 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1681) HIF-1 PF11413.3 KFM00419.1 - 1e-16 59.8 6.9 2.4e-16 58.5 4.8 1.7 1 0 0 1 1 1 1 Hypoxia-inducible factor-1 HLH PF00010.21 KFM00420.1 - 5.4e-05 22.8 0.3 6.4e-05 22.5 0.2 1.1 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pkinase PF00069.20 KFM00421.1 - 1.2e-65 221.2 0.0 2e-65 220.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM00421.1 - 3.1e-36 124.7 0.0 4.6e-36 124.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 KFM00421.1 - 2.7e-30 103.8 31.4 1.8e-15 56.4 4.5 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C2 PF00168.25 KFM00421.1 - 2e-11 43.5 0.1 4.1e-11 42.5 0.1 1.5 1 0 0 1 1 1 1 C2 domain Pkinase_C PF00433.19 KFM00421.1 - 1.6e-09 38.1 0.3 2.8e-09 37.3 0.2 1.4 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KFM00421.1 - 4e-06 26.0 0.0 3.8e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFM00421.1 - 0.076 12.0 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFM00421.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DZR PF12773.2 KFM00421.1 - 1.1 9.1 13.9 0.05 13.4 1.5 2.8 2 0 0 2 2 2 0 Double zinc ribbon FYVE_2 PF02318.11 KFM00421.1 - 6.4 6.6 19.4 9.2 6.2 5.1 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger Aa_trans PF01490.13 KFM00422.1 - 6.3e-74 248.8 38.3 7.9e-74 248.5 26.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TRIQK PF15168.1 KFM00422.1 - 6.7 6.7 5.6 1.9 8.4 0.2 2.9 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family Met_10 PF02475.11 KFM00423.1 - 8e-67 224.7 0.0 1.2e-66 224.0 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_15 PF09445.5 KFM00423.1 - 0.00022 20.8 0.0 0.00049 19.6 0.0 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 KFM00423.1 - 0.00037 20.5 0.0 0.00063 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MethyltransfD12 PF02086.10 KFM00423.1 - 0.004 16.6 0.0 0.0076 15.7 0.0 1.4 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_18 PF12847.2 KFM00423.1 - 0.0048 17.4 0.0 0.0095 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 KFM00423.1 - 0.0068 15.1 0.0 0.03 13.0 0.0 1.8 2 0 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase TRM PF02005.11 KFM00423.1 - 0.013 14.4 0.0 0.025 13.4 0.0 1.4 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase PrmA PF06325.8 KFM00423.1 - 0.17 11.0 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MAT1 PF06391.8 KFM00424.1 - 2.2e-83 278.7 21.6 2.6e-83 278.5 15.0 1.0 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 AAA_23 PF13476.1 KFM00424.1 - 1.8 8.8 15.9 2.3 8.5 11.0 1.3 1 0 0 1 1 1 0 AAA domain Homeobox PF00046.24 KFM00425.1 - 1.5e-14 53.3 1.3 3.8e-14 52.0 0.9 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFM00425.1 - 1.2e-08 34.4 0.5 2.3e-08 33.5 0.3 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 KFM00425.1 - 0.0053 15.7 0.0 0.012 14.6 0.0 1.6 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez SOBP PF15279.1 KFM00425.1 - 0.059 13.7 2.5 0.076 13.3 1.7 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Apc3 PF12895.2 KFM00426.1 - 0.04 14.0 0.5 0.063 13.4 0.3 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 PP2C PF00481.16 KFM00428.1 - 1.4e-87 293.2 0.0 1.8e-87 292.9 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_C PF07830.8 KFM00428.1 - 5.9e-36 122.4 0.1 1.3e-35 121.3 0.1 1.6 1 0 0 1 1 1 1 Protein serine/threonine phosphatase 2C, C-terminal domain PP2C_2 PF13672.1 KFM00428.1 - 0.00013 21.3 0.0 0.00027 20.4 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C adh_short PF00106.20 KFM00429.1 - 3.9e-30 104.9 0.1 5.1e-30 104.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFM00429.1 - 8.4e-14 51.9 0.1 1.1e-13 51.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFM00429.1 - 1.6e-13 50.7 0.0 2.3e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.14 KFM00429.1 - 0.015 14.4 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pecanex_C PF05041.10 KFM00430.1 - 1.8e-49 167.9 0.0 2.9e-49 167.2 0.0 1.3 1 0 0 1 1 1 1 Pecanex protein (C-terminus) RE_MamI PF09567.5 KFM00430.1 - 0.048 12.7 0.2 0.15 11.1 0.0 1.8 2 0 0 2 2 2 0 MamI restriction endonuclease Reticulon PF02453.12 KFM00431.1 - 6.5e-59 198.3 7.8 9e-59 197.8 5.4 1.2 1 0 0 1 1 1 1 Reticulon EI24 PF07264.6 KFM00431.1 - 3.2 7.1 10.2 6 6.2 0.7 2.1 1 1 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) PEP-utilisers_N PF05524.8 KFM00432.1 - 0.1 12.3 3.4 1.4 8.6 0.2 2.2 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal CoaE PF01121.15 KFM00432.1 - 0.14 11.5 1.6 0.19 11.1 0.9 1.3 1 1 0 1 1 1 0 Dephospho-CoA kinase AAA_5 PF07728.9 KFM00432.1 - 0.14 11.8 0.5 0.31 10.7 0.3 1.6 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) ADIP PF11559.3 KFM00432.1 - 0.27 11.1 11.1 1.7 8.5 1.1 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Spectrin PF00435.16 KFM00432.1 - 0.36 11.1 6.0 0.82 9.9 0.5 2.1 2 0 0 2 2 2 0 Spectrin repeat DUF4140 PF13600.1 KFM00432.1 - 0.38 11.2 3.5 3.2 8.2 0.1 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) YjcZ PF13990.1 KFM00432.1 - 0.44 9.6 3.5 0.4 9.7 0.5 1.9 1 1 1 2 2 2 0 YjcZ-like protein COG2 PF06148.6 KFM00432.1 - 0.59 9.9 6.8 1.8 8.4 1.6 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DivIC PF04977.10 KFM00432.1 - 1.5 8.3 7.5 7.1 6.1 0.6 2.4 2 0 0 2 2 2 0 Septum formation initiator TPX2 PF06886.6 KFM00432.1 - 3.2 7.9 9.0 0.57 10.2 3.0 2.1 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) End3 PF12761.2 KFM00432.1 - 3.5 7.2 8.0 0.42 10.2 1.2 2.0 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 eIF3_N PF09440.5 KFM00432.1 - 7.2 6.7 7.6 2.4 8.3 2.6 1.9 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain DUF489 PF04356.7 KFM00433.1 - 0.026 14.1 0.6 0.026 14.1 0.4 2.6 1 1 1 3 3 3 0 Protein of unknown function (DUF489) Endonuc-BglII PF09195.6 KFM00433.1 - 0.072 12.5 2.2 0.092 12.2 1.3 1.4 1 1 0 1 1 1 0 Restriction endonuclease BglII Tup_N PF08581.5 KFM00433.1 - 1.1 9.5 0.1 1.1 9.5 0.0 3.7 4 1 0 4 4 4 0 Tup N-terminal DUF766 PF05571.7 KFM00435.1 - 5.6e-122 406.6 13.9 6.3e-122 406.4 9.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF766) Pro_racemase PF05544.6 KFM00436.1 - 9.1e-57 192.3 0.1 1e-56 192.1 0.1 1.0 1 0 0 1 1 1 1 Proline racemase SNARE PF05739.14 KFM00437.1 - 5.2e-14 51.6 6.8 5.2e-14 51.6 4.7 2.3 2 0 0 2 2 2 1 SNARE domain HD_assoc PF13286.1 KFM00437.1 - 0.054 13.7 0.2 1.9 8.8 0.0 2.5 2 1 0 2 2 2 0 Phosphohydrolase-associated domain Halogen_Hydrol PF10112.4 KFM00437.1 - 0.27 10.6 4.2 1 8.7 0.2 2.2 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Baculo_PEP_C PF04513.7 KFM00437.1 - 0.45 10.3 7.1 0.14 11.9 0.2 2.3 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin-6_N PF09177.6 KFM00437.1 - 2.7 8.4 8.1 4.1 7.8 0.4 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal NPV_P10 PF05531.7 KFM00437.1 - 5.2 7.3 9.5 3.5 7.9 1.7 2.7 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein FUSC-like PF12805.2 KFM00437.1 - 6.2 5.6 6.0 2.5 6.9 0.8 2.3 2 1 0 2 2 2 0 FUSC-like inner membrane protein yccS Seryl_tRNA_N PF02403.17 KFM00437.1 - 6.7 6.7 11.8 0.25 11.3 2.1 2.6 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.7 KFM00437.1 - 7.8 6.3 8.9 3.1 7.6 1.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) V-SNARE PF05008.10 KFM00437.1 - 9 6.5 10.7 0.7 10.1 1.2 2.8 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus TLD PF07534.11 KFM00438.1 - 7.4e-29 100.5 0.0 3.1e-15 56.4 0.0 2.5 2 0 0 2 2 2 2 TLD RabGAP-TBC PF00566.13 KFM00438.1 - 3.1e-23 82.3 0.7 5.4e-23 81.5 0.5 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain WD40 PF00400.27 KFM00439.1 - 7.6e-45 149.2 24.4 8.2e-06 25.5 0.1 11.3 12 0 0 12 12 12 9 WD domain, G-beta repeat Lgl_C PF08596.5 KFM00439.1 - 0.0053 15.2 0.0 0.049 12.0 0.0 2.5 2 1 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal Kelch_4 PF13418.1 KFM00439.1 - 0.038 13.7 0.0 5.3 6.8 0.0 2.8 2 0 0 2 2 2 0 Galactose oxidase, central domain PQQ_3 PF13570.1 KFM00439.1 - 0.049 13.9 11.2 2.2 8.6 0.1 5.9 5 1 1 6 6 6 0 PQQ-like domain Nucleoporin_N PF08801.6 KFM00439.1 - 0.068 11.9 1.0 44 2.6 0.0 3.9 3 1 1 4 4 4 0 Nup133 N terminal like UCH PF00443.24 KFM00440.1 - 1.4e-10 40.7 0.1 1.8e-10 40.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFM00440.1 - 8.4e-08 31.9 0.0 1e-07 31.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rubredoxin PF00301.15 KFM00440.1 - 0.022 14.6 0.8 0.047 13.5 0.6 1.6 1 0 0 1 1 1 0 Rubredoxin zf-MIZ PF02891.15 KFM00440.1 - 2.2 7.8 10.4 0.15 11.5 3.1 2.1 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger BAR PF03114.13 KFM00441.1 - 4.8e-55 186.5 6.3 8.1e-55 185.8 4.4 1.4 1 0 0 1 1 1 1 BAR domain RhoGAP PF00620.22 KFM00441.1 - 6.2e-46 155.7 0.1 3.5e-45 153.3 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain DUF2935 PF11155.3 KFM00441.1 - 0.2 11.7 1.1 1.1 9.4 0.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) p450 PF00067.17 KFM00442.1 - 2.9e-130 434.9 0.0 3.6e-130 434.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.27 KFM00443.1 - 3.2e-30 102.8 10.2 1.3e-08 34.3 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.2 KFM00443.1 - 2.6e-05 23.8 0.7 6.3e-05 22.6 0.3 1.8 2 0 0 2 2 2 1 F-box-like Nup160 PF11715.3 KFM00443.1 - 0.00042 18.5 0.1 0.12 10.5 0.0 2.9 2 1 0 3 3 3 2 Nucleoporin Nup120/160 F-box PF00646.28 KFM00443.1 - 0.003 17.1 0.4 0.0066 16.0 0.3 1.5 1 0 0 1 1 1 1 F-box domain DUF846 PF05832.7 KFM00444.1 - 1e-54 184.0 9.7 1.2e-54 183.8 6.8 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) TMEM192 PF14802.1 KFM00444.1 - 0.09 11.6 0.5 0.17 10.7 0.3 1.3 1 0 0 1 1 1 0 TMEM192 family Tektin PF03148.9 KFM00445.1 - 1.4e-146 487.9 30.9 1.6e-146 487.7 21.4 1.0 1 0 0 1 1 1 1 Tektin family Dna2 PF08696.6 KFM00445.1 - 0.049 12.9 0.3 0.049 12.9 0.2 2.1 2 0 0 2 2 2 0 DNA replication factor Dna2 BLOC1_2 PF10046.4 KFM00445.1 - 0.71 10.0 8.2 0.16 12.1 0.4 3.3 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PMP22_Claudin PF00822.15 KFM00446.1 - 5.3e-46 156.3 17.1 5.9e-46 156.1 11.8 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFM00446.1 - 1.1e-07 31.7 20.1 1.1e-07 31.7 13.9 1.7 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 KFM00446.1 - 0.029 13.9 13.7 0.047 13.3 9.2 1.5 1 1 0 1 1 1 0 Amastin surface glycoprotein Claudin_3 PF06653.6 KFM00446.1 - 0.08 12.6 16.8 0.1 12.2 11.7 1.1 1 0 0 1 1 1 0 Tight junction protein, Claudin-like L_HGMIC_fpl PF10242.4 KFM00446.1 - 0.23 11.4 16.2 0.55 10.2 11.2 1.8 1 1 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein PepSY_TM PF03929.11 KFM00446.1 - 0.25 11.7 0.1 0.25 11.7 0.1 4.0 4 2 0 4 4 3 0 PepSY-associated TM helix MARVEL PF01284.18 KFM00446.1 - 0.38 10.5 15.2 1.3 8.8 4.2 2.2 2 0 0 2 2 2 0 Membrane-associating domain DUF21 PF01595.15 KFM00446.1 - 0.39 9.9 0.0 0.39 9.9 0.0 2.6 2 2 0 2 2 1 0 Domain of unknown function DUF21 DUF2207 PF09972.4 KFM00446.1 - 0.4 9.2 10.4 0.17 10.3 3.2 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF2723 PF11028.3 KFM00446.1 - 0.71 9.3 10.2 0.28 10.6 4.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2723) 7TMR-DISM_7TM PF07695.6 KFM00446.1 - 3.6 7.2 21.7 28 4.2 14.5 2.3 1 1 0 1 1 1 0 7TM diverse intracellular signalling DUF373 PF04123.8 KFM00446.1 - 5.2 5.9 10.0 0.48 9.3 2.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF373) DUF3671 PF12420.3 KFM00446.1 - 7.7 6.5 10.4 42 4.2 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function Clc-like PF07062.7 KFM00446.1 - 8.9 5.4 18.5 1.3 8.2 7.4 2.4 1 1 1 2 2 2 0 Clc-like Sulfotransfer_1 PF00685.22 KFM00448.1 - 1.4e-31 109.7 0.0 1.7e-31 109.4 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_2 PF03567.9 KFM00448.1 - 0.0065 16.1 0.0 0.06 13.0 0.0 2.0 2 0 0 2 2 2 1 Sulfotransferase family RICTOR_M PF14666.1 KFM00448.1 - 0.13 11.2 0.1 0.22 10.4 0.1 1.3 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain UbiA PF01040.13 KFM00449.1 - 2.8e-29 102.1 18.1 3.6e-29 101.7 12.6 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Sulfotransfer_1 PF00685.22 KFM00450.1 - 1.4e-31 109.7 0.0 1.7e-31 109.4 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_2 PF03567.9 KFM00450.1 - 0.0065 16.1 0.0 0.06 13.0 0.0 2.0 2 0 0 2 2 2 1 Sulfotransferase family RICTOR_M PF14666.1 KFM00450.1 - 0.13 11.2 0.1 0.22 10.4 0.1 1.3 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain GPCR_chapero_1 PF11904.3 KFM00452.1 - 1.4e-48 165.6 0.1 1.5e-48 165.5 0.0 1.0 1 0 0 1 1 1 1 GPCR-chaperone zf-CXXC PF02008.15 KFM00453.1 - 1.1e-12 47.5 21.5 1.1e-12 47.5 14.9 2.7 2 0 0 2 2 2 1 CXXC zinc finger domain F-box PF00646.28 KFM00453.1 - 9.3e-09 34.7 4.4 9.3e-09 34.7 3.1 2.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KFM00453.1 - 3.2e-08 33.1 6.7 6.9e-08 32.0 4.6 1.6 1 0 0 1 1 1 1 F-box-like JmjC PF02373.17 KFM00453.1 - 3.4e-05 24.0 3.9 0.00023 21.3 0.4 3.1 2 1 0 2 2 2 1 JmjC domain, hydroxylase LRR_1 PF00560.28 KFM00453.1 - 0.0005 19.7 5.3 19 5.7 0.1 6.5 5 1 1 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.1 KFM00453.1 - 0.00089 19.0 9.4 3.8 7.8 0.1 6.2 7 0 0 7 7 6 2 Leucine Rich repeat FAM176 PF14851.1 KFM00453.1 - 0.017 14.8 0.8 2.1 7.9 0.1 2.6 2 0 0 2 2 2 0 FAM176 family Myc_N PF01056.13 KFM00453.1 - 0.027 13.6 6.4 0.97 8.5 0.2 2.4 2 0 0 2 2 2 0 Myc amino-terminal region Cupin_8 PF13621.1 KFM00453.1 - 0.048 13.1 0.2 0.34 10.3 0.1 2.1 1 1 0 1 1 1 0 Cupin-like domain Cupin_1 PF00190.17 KFM00453.1 - 0.067 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Cupin Nucleoplasmin PF03066.10 KFM00453.1 - 0.65 9.5 9.5 0.99 8.9 0.2 2.4 2 0 0 2 2 2 0 Nucleoplasmin LRR_8 PF13855.1 KFM00453.1 - 1 9.1 12.2 4.3 7.1 0.0 4.2 3 2 1 5 5 5 0 Leucine rich repeat LRR_4 PF12799.2 KFM00453.1 - 1.9 8.2 13.5 12 5.6 0.1 4.4 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 KFM00453.1 - 2.2 8.8 10.9 77 4.1 0.2 6.1 7 0 0 7 7 6 0 Leucine rich repeat 7tm_1 PF00001.16 KFM00454.1 - 5.2e-06 25.7 21.9 2.8e-05 23.4 15.2 2.2 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2834 PF11196.3 KFM00454.1 - 0.055 13.6 5.1 0.46 10.6 3.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2834) 7tm_1 PF00001.16 KFM00455.1 - 8.9e-07 28.3 21.9 2.3e-06 26.9 15.2 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF373 PF04123.8 KFM00455.1 - 2.1 7.2 5.7 2.5 7.0 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Tmemb_170 PF10190.4 KFM00455.1 - 2.9 8.0 11.3 1.6 8.8 5.2 2.3 1 1 1 2 2 2 0 Putative transmembrane protein 170 CTP_transf_1 PF01148.15 KFM00455.1 - 7.7 6.0 15.5 1.7 8.2 7.9 1.7 1 1 1 2 2 2 0 Cytidylyltransferase family 7tm_1 PF00001.16 KFM00456.1 - 2.6e-12 46.4 19.5 1.1e-11 44.4 13.5 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Mtc PF03820.12 KFM00456.1 - 0.066 11.8 0.1 0.093 11.3 0.1 1.2 1 0 0 1 1 1 0 Tricarboxylate carrier DUF2306 PF10067.4 KFM00456.1 - 0.58 10.3 5.5 1.2 9.2 3.7 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2306) 7tm_1 PF00001.16 KFM00457.1 - 2.1e-07 30.3 15.1 8.8e-07 28.3 10.4 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srbc PF10316.4 KFM00457.1 - 0.013 14.7 8.8 0.066 12.4 5.5 2.1 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srbc 7tm_1 PF00001.16 KFM00458.1 - 5.1e-09 35.6 15.4 2.1e-08 33.6 10.7 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srbc PF10316.4 KFM00458.1 - 0.00048 19.4 0.1 0.00048 19.4 0.1 2.3 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc 7tm_4 PF13853.1 KFM00459.1 - 6.3e-43 146.0 11.2 6.3e-43 146.0 7.7 2.9 2 1 1 3 3 3 1 Olfactory receptor 7tm_1 PF00001.16 KFM00459.1 - 8.1e-32 110.3 23.8 8.1e-32 110.3 16.5 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 KFM00460.1 - 2e-41 141.1 12.4 2e-41 141.1 8.6 2.4 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFM00460.1 - 2.5e-28 98.9 19.6 4e-28 98.2 13.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 KFM00461.1 - 1.3e-34 119.0 18.9 1.3e-34 119.0 13.1 2.4 2 1 1 3 3 3 1 Olfactory receptor 7tm_1 PF00001.16 KFM00461.1 - 6.1e-31 107.4 27.6 8.8e-31 106.9 19.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM00461.1 - 0.001 18.2 24.4 0.0028 16.8 16.9 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx SHP PF03579.8 KFM00461.1 - 0.082 12.2 0.4 0.082 12.2 0.2 2.5 2 1 1 3 3 3 0 Small hydrophobic protein 7tm_4 PF13853.1 KFM00462.1 - 2.2e-44 150.7 15.1 2.2e-44 150.7 10.4 2.5 2 1 1 3 3 3 1 Olfactory receptor 7tm_1 PF00001.16 KFM00462.1 - 1e-30 106.7 26.0 1e-30 106.7 18.0 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Pex2_Pex12 PF04757.9 KFM00462.1 - 1.5 8.2 4.6 17 4.7 0.0 2.8 2 1 1 3 3 3 0 Pex2 / Pex12 amino terminal region 7tm_4 PF13853.1 KFM00463.1 - 6.7e-20 71.3 4.1 7.5e-20 71.1 2.9 1.0 1 0 0 1 1 1 1 Olfactory receptor Ferritin PF00210.19 KFM00464.1 - 1.2e-44 151.5 4.4 1.4e-44 151.3 3.1 1.0 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.12 KFM00464.1 - 0.007 16.6 1.0 0.0098 16.2 0.7 1.3 1 1 0 1 1 1 1 Rubrerythrin Bestrophin PF01062.16 KFM00465.1 - 1.7e-104 348.8 4.4 2e-104 348.6 3.0 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Sec2p PF06428.6 KFM00466.1 - 2.4e-26 91.5 6.2 5.4e-26 90.3 4.3 1.7 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p IATP PF04568.7 KFM00466.1 - 0.01 15.8 4.2 0.029 14.3 2.9 1.9 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP APG6 PF04111.7 KFM00466.1 - 0.14 11.1 12.5 0.2 10.6 8.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 KFM00466.1 - 0.17 10.8 6.4 0.25 10.2 4.4 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Tropomyosin_1 PF12718.2 KFM00466.1 - 0.37 10.6 17.9 0.75 9.6 12.4 1.5 1 1 0 1 1 1 0 Tropomyosin like DUF4407 PF14362.1 KFM00466.1 - 0.38 9.6 4.9 0.51 9.2 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cob_adeno_trans PF01923.13 KFM00466.1 - 0.69 9.6 5.2 0.76 9.5 1.0 2.1 1 1 2 3 3 3 0 Cobalamin adenosyltransferase Spc7 PF08317.6 KFM00466.1 - 1.1 7.8 11.7 1.7 7.1 8.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 KFM00466.1 - 1.2 8.6 12.3 2.1 7.9 8.5 1.3 1 0 0 1 1 1 0 IncA protein HSP70 PF00012.15 KFM00466.1 - 2.1 6.1 7.3 3 5.6 5.1 1.1 1 0 0 1 1 1 0 Hsp70 protein Mnd1 PF03962.10 KFM00466.1 - 4.4 6.9 13.3 2.9 7.5 7.9 1.6 1 1 0 1 1 1 0 Mnd1 family DUF4140 PF13600.1 KFM00466.1 - 9.3 6.7 11.9 12 6.3 2.2 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) FA_desaturase PF00487.19 KFM00467.1 - 6.4e-37 127.3 29.5 6.4e-37 127.3 20.4 1.6 1 1 1 2 2 2 2 Fatty acid desaturase MIP-T3 PF10243.4 KFM00470.1 - 0.1 11.0 19.6 0.1 11.0 13.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 GAGA_bind PF06217.7 KFM00470.1 - 0.12 12.2 6.3 0.12 12.3 4.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family FLO_LFY PF01698.11 KFM00470.1 - 0.13 11.1 6.2 0.13 11.0 4.3 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein RR_TM4-6 PF06459.7 KFM00470.1 - 0.13 12.1 10.9 0.14 12.0 7.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIF_alpha PF05793.7 KFM00470.1 - 0.41 8.9 23.4 0.53 8.5 16.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Herpes_DNAp_acc PF04929.7 KFM00470.1 - 0.43 9.4 11.4 0.54 9.1 7.9 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Apt1 PF10351.4 KFM00470.1 - 0.84 8.4 7.2 0.89 8.3 5.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SRP-alpha_N PF04086.8 KFM00470.1 - 2.3 7.5 18.0 2.9 7.2 12.4 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DDHD PF02862.12 KFM00470.1 - 2.5 7.8 7.1 3 7.5 4.9 1.2 1 0 0 1 1 1 0 DDHD domain PDZ PF00595.19 KFM00471.1 - 1e-21 76.8 0.2 2e-17 63.1 0.1 2.2 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM00471.1 - 7.2e-10 38.6 0.0 8.6e-09 35.1 0.0 2.2 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.1 KFM00471.1 - 0.13 12.1 0.0 0.69 9.7 0.0 2.1 2 0 0 2 2 2 0 Tricorn protease PDZ domain DUF3534 PF12053.3 KFM00472.1 - 5.1e-15 55.6 0.0 5.5e-15 55.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3534) FAM176 PF14851.1 KFM00473.1 - 0.03 13.9 0.8 0.06 13.0 0.6 1.4 1 0 0 1 1 1 0 FAM176 family DUF2269 PF10027.4 KFM00473.1 - 0.079 12.7 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) V-set PF07686.12 KFM00474.1 - 5.7e-13 48.7 0.1 7.6e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.1 KFM00474.1 - 0.0044 17.5 0.0 0.0088 16.5 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain stn_TNFRSF12A PF12191.3 KFM00474.1 - 0.0055 16.7 0.1 0.016 15.2 0.0 1.7 2 0 0 2 2 2 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Herpes_gE PF02480.11 KFM00474.1 - 0.0056 14.9 0.1 0.046 11.9 0.0 2.0 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E I-set PF07679.11 KFM00474.1 - 0.089 12.6 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin I-set domain V-set PF07686.12 KFM00475.1 - 4.4e-05 23.3 0.3 4.4e-05 23.3 0.2 1.5 2 0 0 2 2 2 1 Immunoglobulin V-set domain PsbJ PF01788.12 KFM00475.1 - 0.0084 15.6 0.1 0.017 14.6 0.1 1.5 1 0 0 1 1 1 1 PsbJ RA PF00788.18 KFM00476.1 - 1.3e-13 51.2 2.5 3.6e-13 49.8 0.1 2.7 2 1 1 3 3 3 1 Ras association (RalGDS/AF-6) domain PH PF00169.24 KFM00476.1 - 7.3e-09 35.7 0.1 2.1e-08 34.3 0.1 1.8 1 0 0 1 1 1 1 PH domain FERM_N PF09379.5 KFM00476.1 - 0.0032 17.4 0.2 0.0095 15.9 0.1 1.9 1 0 0 1 1 1 1 FERM N-terminal domain PH_11 PF15413.1 KFM00476.1 - 8 6.7 9.9 0.23 11.7 1.1 2.9 3 1 0 3 3 3 0 Pleckstrin homology domain Abi_HHR PF07815.9 KFM00477.1 - 1.9e-34 117.6 0.1 3.3e-34 116.8 0.1 1.4 1 0 0 1 1 1 1 Abl-interactor HHR SH3_1 PF00018.23 KFM00477.1 - 2.5e-09 36.3 0.8 4e-09 35.7 0.5 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFM00477.1 - 4.6e-07 29.3 0.1 7.7e-07 28.5 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFM00477.1 - 0.002 17.5 0.1 0.0041 16.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain p450 PF00067.17 KFM00478.1 - 4.3e-45 154.0 0.1 5.8e-45 153.6 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S51 PF03575.12 KFM00479.1 - 2.6e-44 150.6 0.0 3.1e-44 150.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase family S51 Beach PF02138.13 KFM00481.1 - 5.1e-114 380.2 0.2 5.7e-114 380.1 0.2 1.0 1 0 0 1 1 1 1 Beige/BEACH domain RdRP_4 PF02123.11 KFM00481.1 - 0.038 12.7 0.0 0.049 12.3 0.0 1.1 1 0 0 1 1 1 0 Viral RNA-directed RNA-polymerase CDC14 PF08045.6 KFM00482.1 - 0.00024 20.3 3.7 0.35 9.9 0.0 3.4 3 0 0 3 3 3 2 Cell division control protein 14, SIN component ROKNT PF08067.6 KFM00483.1 - 0.02 14.7 0.8 0.035 13.9 0.1 1.7 2 0 0 2 2 2 0 ROKNT (NUC014) domain SOCS PF12610.3 KFM00484.1 - 5.5 7.3 11.7 0.46 10.8 4.3 2.1 2 1 0 2 2 2 0 Suppressor of cytokine signalling Iso_dh PF00180.15 KFM00485.1 - 5.8e-78 262.2 0.0 7e-78 261.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PIP5K PF01504.13 KFM00486.1 - 1.1e-66 224.5 0.3 2.5e-66 223.3 0.2 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 KFM00486.1 - 1e-32 113.4 0.3 1.9e-32 112.5 0.2 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 KFM00486.1 - 2.7e-16 59.2 14.1 2.7e-16 59.2 9.8 2.2 2 0 0 2 2 2 1 FYVE zinc finger DEP PF00610.16 KFM00486.1 - 0.00017 21.2 0.0 0.00053 19.6 0.0 1.9 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Thioredoxin PF00085.15 KFM00487.1 - 7.3e-95 311.5 0.0 3.9e-25 87.5 0.1 5.9 6 0 0 6 6 6 4 Thioredoxin DnaJ PF00226.26 KFM00487.1 - 3.7e-23 81.0 3.1 7.3e-23 80.0 2.1 1.5 1 0 0 1 1 1 1 DnaJ domain Thioredoxin_8 PF13905.1 KFM00487.1 - 1.2e-18 66.9 4.1 0.00085 19.3 0.0 5.9 5 1 1 6 6 6 4 Thioredoxin-like Thioredoxin_2 PF13098.1 KFM00487.1 - 1.2e-17 64.1 3.6 0.0023 18.0 0.0 6.7 4 3 0 4 4 4 4 Thioredoxin-like domain Thioredoxin_6 PF13848.1 KFM00487.1 - 4.3e-16 59.2 0.0 1.9e-05 24.5 0.0 3.8 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KFM00487.1 - 1.6e-12 47.2 2.7 0.032 14.2 0.0 4.7 4 0 0 4 4 4 3 Thioredoxin-like Redoxin PF08534.5 KFM00487.1 - 1.6e-08 34.1 2.8 0.058 12.9 0.0 4.2 4 0 0 4 4 4 3 Redoxin AhpC-TSA PF00578.16 KFM00487.1 - 4.6e-07 29.5 3.9 0.53 9.9 0.0 4.8 5 0 0 5 5 5 3 AhpC/TSA family Thioredoxin_9 PF14595.1 KFM00487.1 - 1.4e-06 27.8 0.4 0.51 9.8 0.0 4.0 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_3 PF13192.1 KFM00487.1 - 0.0067 16.2 0.0 2.3 8.0 0.0 3.2 3 0 0 3 3 3 1 Thioredoxin domain Calsequestrin PF01216.12 KFM00487.1 - 0.015 14.0 0.0 2.6 6.6 0.0 2.3 2 0 0 2 2 2 0 Calsequestrin RMMBL PF07521.7 KFM00487.1 - 0.029 14.2 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA-metabolising metallo-beta-lactamase Thioredoxin_4 PF13462.1 KFM00487.1 - 0.049 13.6 1.0 8 6.4 0.0 3.9 3 1 1 4 4 4 0 Thioredoxin PDEase_I PF00233.14 KFM00488.1 - 2.8e-98 328.4 11.2 4e-98 327.9 7.0 1.7 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I_N PF08499.7 KFM00488.1 - 3.8e-27 93.9 0.0 7.4e-27 93.0 0.0 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase N-terminal FAA_hydrolase_N PF09298.6 KFM00488.1 - 0.022 14.7 0.4 0.083 12.8 0.1 2.0 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal DARPP-32 PF05395.7 KFM00489.1 - 1.9e-34 119.3 6.5 2.1e-34 119.1 4.5 1.0 1 0 0 1 1 1 1 Protein phosphatase inhibitor 1/DARPP-32 SSFA2_C PF14723.1 KFM00490.1 - 2.2e-81 271.8 6.5 2.2e-81 271.8 4.5 2.1 2 0 0 2 2 2 1 Sperm-specific antigen 2 C-terminus KRAP_IP3R_bind PF14722.1 KFM00490.1 - 1.7e-68 229.2 2.2 1.7e-68 229.2 1.5 2.4 3 0 0 3 3 3 1 Ki-ras-induced actin-interacting protein-IP3R-interacting domain Neuro_bHLH PF12533.3 KFM00491.1 - 4.4e-46 156.5 0.5 7e-46 155.9 0.3 1.3 1 0 0 1 1 1 1 Neuronal helix-loop-helix transcription factor HLH PF00010.21 KFM00491.1 - 6.9e-16 57.6 1.1 6.9e-16 57.6 0.8 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain YL1 PF05764.8 KFM00491.1 - 0.023 14.3 7.9 0.026 14.1 5.4 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Spt5_N PF11942.3 KFM00491.1 - 0.62 10.7 13.4 0.9 10.2 9.3 1.2 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DAGK_cat PF00781.19 KFM00492.1 - 1.6e-19 69.6 0.1 4e-19 68.3 0.1 1.7 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain CD45 PF12567.3 KFM00492.1 - 0.5 10.2 3.5 0.22 11.4 0.5 1.8 2 0 0 2 2 2 0 Leukocyte receptor CD45 Integrin_alpha2 PF08441.7 KFM00493.1 - 1.2e-67 228.8 1.2 1.3e-66 225.3 0.4 1.9 1 1 1 2 2 2 1 Integrin alpha Integrin_alpha PF00357.15 KFM00493.1 - 6e-05 22.5 0.5 0.00013 21.4 0.3 1.6 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region Rax2 PF12768.2 KFM00493.1 - 0.024 13.8 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Na_H_Exchanger PF00999.16 KFM00494.1 - 2.8e-80 269.6 44.3 3.2e-80 269.4 30.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family LRR_8 PF13855.1 KFM00495.1 - 0.001 18.8 3.0 0.001 18.8 2.1 3.6 2 1 1 3 3 3 1 Leucine rich repeat LRR_4 PF12799.2 KFM00495.1 - 0.0017 17.9 6.5 0.55 9.9 0.9 3.8 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KFM00495.1 - 0.0031 17.4 3.3 45 4.5 0.1 5.0 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.28 KFM00495.1 - 0.029 14.3 7.6 28 5.2 0.0 5.2 4 1 0 4 4 4 0 Leucine Rich Repeat AA_permease PF00324.16 KFM00496.1 - 1.9e-49 168.2 21.0 2.5e-33 115.1 3.5 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 KFM00496.1 - 1.3e-19 70.0 25.0 6.2e-19 67.8 17.3 1.9 1 1 0 1 1 1 1 Amino acid permease R3H PF01424.17 KFM00497.1 - 1.5e-16 59.8 0.1 3.5e-16 58.6 0.1 1.6 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 KFM00497.1 - 2.5e-10 40.0 184.3 2.1e-05 24.3 8.0 12.9 10 3 2 12 12 12 7 NF-X1 type zinc finger COG7 PF10191.4 KFM00498.1 - 0.06 11.2 0.3 0.056 11.3 0.2 1.0 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) Laminin_II PF06009.7 KFM00498.1 - 0.067 12.9 0.2 0.067 12.9 0.1 1.1 1 0 0 1 1 1 0 Laminin Domain II Hus1 PF04005.7 KFM00501.1 - 1.7e-85 286.5 0.4 1.9e-85 286.3 0.3 1.0 1 0 0 1 1 1 1 Hus1-like protein PTB PF08416.8 KFM00502.1 - 1.4e-43 147.8 0.0 2.4e-43 147.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PTEN_C2 PF10409.4 KFM00502.1 - 7.7e-12 45.0 0.0 3.3e-11 43.0 0.0 2.0 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein SH2 PF00017.19 KFM00502.1 - 1.1e-09 37.9 0.0 3e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 SH2 domain Y_phosphatase PF00102.22 KFM00502.1 - 0.014 14.7 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KFM00502.1 - 0.03 14.5 0.0 0.061 13.5 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family RVT_1 PF00078.22 KFM00503.1 - 0.042 13.1 0.0 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) p25-alpha PF05517.7 KFM00505.1 - 2.1e-57 193.6 4.3 2.4e-57 193.5 3.0 1.0 1 0 0 1 1 1 1 p25-alpha EF-hand_8 PF13833.1 KFM00505.1 - 0.023 14.2 0.1 0.12 11.9 0.1 2.1 2 0 0 2 2 2 0 EF-hand domain pair Rep_3 PF01051.16 KFM00505.1 - 0.03 13.9 0.4 0.038 13.5 0.3 1.1 1 0 0 1 1 1 0 Initiator Replication protein Drf_FH3 PF06367.11 KFM00505.1 - 0.037 13.4 0.0 0.046 13.1 0.0 1.2 1 0 0 1 1 1 0 Diaphanous FH3 Domain DUF573 PF04504.9 KFM00505.1 - 0.15 12.3 1.8 0.27 11.5 1.2 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF573 RVT_1 PF00078.22 KFM00506.1 - 2.3e-13 49.9 0.0 3.9e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3512 PF12024.3 KFM00507.1 - 6.5e-89 297.4 0.7 6.5e-89 297.4 0.5 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3512) Bromodomain PF00439.20 KFM00507.1 - 4.7e-23 80.8 0.1 3.4e-22 78.1 0.1 2.2 2 0 0 2 2 2 1 Bromodomain MIP-T3 PF10243.4 KFM00507.1 - 0.0031 16.0 13.7 0.0031 16.0 9.5 1.4 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 Phage_GPD PF05954.6 KFM00507.1 - 0.047 12.8 1.2 0.18 10.9 0.8 1.8 2 0 0 2 2 2 0 Phage late control gene D protein (GPD) SR-25 PF10500.4 KFM00507.1 - 2 7.8 23.9 0.018 14.5 9.9 2.4 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF1510 PF07423.6 KFM00507.1 - 2 7.7 16.8 0.54 9.5 9.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 KFM00507.1 - 3.3 5.6 13.2 5.2 4.9 9.2 1.2 1 0 0 1 1 1 0 CDC45-like protein NARP1 PF12569.3 KFM00507.1 - 8.3 5.0 18.1 15 4.1 12.5 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 AAA PF00004.24 KFM00508.1 - 3.4e-32 111.4 0.0 5.4e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFM00508.1 - 2.9e-08 33.9 0.0 7.4e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFM00508.1 - 9.4e-08 32.9 0.1 5e-07 30.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KFM00508.1 - 2.3e-07 31.1 0.4 3.9e-06 27.1 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.1 KFM00508.1 - 1.4e-06 28.4 0.0 2.5e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 KFM00508.1 - 3e-05 23.9 0.1 7.5e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFM00508.1 - 3.5e-05 23.7 0.1 7.9e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 KFM00508.1 - 4.1e-05 22.7 0.1 0.038 12.9 0.0 2.3 1 1 1 2 2 2 2 KAP family P-loop domain Arch_ATPase PF01637.13 KFM00508.1 - 4.9e-05 23.1 0.9 0.0089 15.7 0.7 2.4 1 1 0 1 1 1 1 Archaeal ATPase AAA_25 PF13481.1 KFM00508.1 - 8.2e-05 22.0 0.5 0.022 14.1 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 KFM00508.1 - 0.00013 21.6 0.0 0.00028 20.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_24 PF13479.1 KFM00508.1 - 0.00017 21.2 0.0 0.00056 19.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFM00508.1 - 0.0004 20.1 0.1 0.0013 18.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) UPF0079 PF02367.12 KFM00508.1 - 0.00057 19.5 0.0 0.0013 18.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 KFM00508.1 - 0.00073 18.9 0.0 0.0017 17.8 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 KFM00508.1 - 0.00081 18.5 0.0 0.0043 16.1 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 KFM00508.1 - 0.002 18.1 0.0 0.0046 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KFM00508.1 - 0.0021 18.2 0.0 0.0051 16.9 0.0 1.7 1 0 0 1 1 1 1 RNA helicase NACHT PF05729.7 KFM00508.1 - 0.0023 17.6 0.2 0.0073 15.9 0.1 2.0 1 1 0 1 1 1 1 NACHT domain Viral_helicase1 PF01443.13 KFM00508.1 - 0.003 17.1 0.0 0.0067 15.9 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.8 KFM00508.1 - 0.0038 16.1 0.1 0.015 14.2 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 KFM00508.1 - 0.0041 17.4 0.0 0.01 16.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter PduV-EutP PF10662.4 KFM00508.1 - 0.0055 16.2 0.0 0.014 14.8 0.0 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_11 PF13086.1 KFM00508.1 - 0.0059 16.2 0.0 0.013 15.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KFM00508.1 - 0.0075 15.8 0.0 0.021 14.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KFM00508.1 - 0.0082 15.2 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin TIP49 PF06068.8 KFM00508.1 - 0.0083 14.8 0.0 0.014 14.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus KaiC PF06745.8 KFM00508.1 - 0.011 14.8 0.1 0.57 9.2 0.0 2.4 2 0 0 2 2 2 0 KaiC DUF2075 PF09848.4 KFM00508.1 - 0.012 14.6 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 KFM00508.1 - 0.016 14.4 0.0 0.081 12.1 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.16 KFM00508.1 - 0.025 13.7 0.0 0.11 11.5 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 KFM00508.1 - 0.034 14.0 0.0 0.075 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) MobB PF03205.9 KFM00508.1 - 0.045 13.4 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Zot PF05707.7 KFM00508.1 - 0.047 13.1 0.2 0.2 11.1 0.1 1.9 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_23 PF13476.1 KFM00508.1 - 0.061 13.6 0.6 0.18 12.0 0.0 1.8 2 1 0 2 2 1 0 AAA domain AAA_3 PF07726.6 KFM00508.1 - 0.073 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.20 KFM00509.1 - 2.7e-49 167.6 0.0 4.2e-49 167.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM00509.1 - 1.8e-32 112.4 0.0 2.4e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TGF_beta_GS PF08515.7 KFM00509.1 - 2.6e-17 61.8 0.6 5e-17 60.9 0.4 1.5 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.18 KFM00509.1 - 1.5e-12 47.9 5.7 3.7e-12 46.7 4.0 1.7 1 0 0 1 1 1 1 Activin types I and II receptor domain APH PF01636.18 KFM00509.1 - 0.0089 15.7 0.0 0.023 14.4 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kazal_2 PF07648.10 KFM00510.1 - 9.6e-13 47.8 41.3 3.7e-06 26.7 1.7 5.7 5 0 0 5 5 5 3 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 KFM00510.1 - 4.6e-11 42.5 34.3 0.0001 22.2 3.1 5.7 3 1 1 4 4 4 3 Kazal-type serine protease inhibitor domain VWC PF00093.13 KFM00510.1 - 0.0055 16.7 4.1 0.0055 16.7 2.8 9.7 7 3 2 9 9 9 2 von Willebrand factor type C domain Ldl_recept_a PF00057.13 KFM00510.1 - 0.009 15.8 4.0 0.009 15.8 2.8 6.8 5 1 1 6 6 6 2 Low-density lipoprotein receptor domain class A DNA_pol_E_B PF04042.11 KFM00510.1 - 0.02 14.1 0.0 0.036 13.3 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B Sod_Fe_C PF02777.13 KFM00511.1 - 2.6e-44 149.4 0.1 4.6e-44 148.5 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KFM00511.1 - 2.9e-33 113.9 3.5 4.6e-33 113.3 2.4 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Fmp27_WPPW PF10359.4 KFM00512.1 - 0.0013 17.2 8.9 0.0013 17.2 6.2 2.2 1 1 1 2 2 2 1 RNA pol II promoter Fmp27 protein domain AAA_13 PF13166.1 KFM00512.1 - 0.0073 14.8 17.0 0.011 14.2 11.8 1.2 1 0 0 1 1 1 1 AAA domain DUF1978 PF09321.5 KFM00512.1 - 0.12 11.7 15.5 0.023 14.1 4.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1978) Atg14 PF10186.4 KFM00512.1 - 0.6 9.0 25.0 1.5 7.6 6.2 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 ADIP PF11559.3 KFM00512.1 - 0.76 9.6 34.8 0.43 10.4 5.0 3.7 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding Lipoprotein_7 PF01540.11 KFM00512.1 - 1 8.3 7.6 4.1 6.3 5.3 1.9 1 1 0 1 1 1 0 Adhesin lipoprotein DUF1515 PF07439.6 KFM00512.1 - 2 8.2 4.9 0.67 9.7 0.2 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) DICT PF10069.4 KFM00512.1 - 3.2 7.2 10.7 0.24 10.9 3.3 2.2 2 1 0 2 2 2 0 Sensory domain found in DIguanylate Cyclases & Two-component systems TMF_TATA_bd PF12325.3 KFM00512.1 - 3.7 7.2 26.6 0.26 11.0 7.2 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.7 KFM00512.1 - 5.3 6.8 12.4 0.12 12.2 2.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) APG6 PF04111.7 KFM00512.1 - 5.4 5.9 28.9 1.2 8.0 4.2 2.4 2 0 0 2 2 2 0 Autophagy protein Apg6 Thiolase_N PF00108.18 KFM00513.1 - 8.2e-88 293.7 1.4 1.1e-87 293.3 1.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KFM00513.1 - 5.8e-50 167.8 0.7 1.1e-49 166.9 0.5 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KFM00513.1 - 0.00039 19.9 3.5 0.0004 19.9 0.9 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Dodecin PF07311.7 KFM00513.1 - 0.0014 18.5 0.1 0.0034 17.3 0.1 1.6 1 0 0 1 1 1 1 Dodecin ACP_syn_III_C PF08541.5 KFM00513.1 - 0.0018 18.2 0.1 0.0061 16.5 0.1 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Cpn60_TCP1 PF00118.19 KFM00514.1 - 2.5e-141 471.6 14.4 2.9e-141 471.4 10.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CAF1 PF04857.15 KFM00515.1 - 5.5e-46 157.0 0.1 7.3e-46 156.6 0.1 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease 7tm_1 PF00001.16 KFM00516.1 - 1.2e-26 93.4 25.8 1.2e-26 93.4 17.9 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 KFM00516.1 - 4.6e-08 32.5 21.1 4.6e-08 32.5 14.6 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Serpentine_r_xa PF03383.10 KFM00516.1 - 0.0068 16.1 14.0 0.0068 16.1 9.7 2.9 1 1 2 3 3 3 1 Caenorhabditis serpentine receptor-like protein, class xa ISK_Channel PF02060.10 KFM00516.1 - 0.12 11.9 1.0 1.4 8.5 0.0 2.5 2 1 1 3 3 3 0 Slow voltage-gated potassium channel 7TM_GPCR_Srbc PF10316.4 KFM00516.1 - 6.4 5.9 33.6 68 2.5 20.5 3.0 1 1 2 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srbc CIMR PF00878.13 KFM00517.1 - 0 1274.5 91.4 4e-55 185.5 1.4 16.2 16 0 0 16 16 16 16 Cation-independent mannose-6-phosphate receptor repeat fn2 PF00040.14 KFM00517.1 - 2.8e-18 65.6 7.4 1.1e-17 63.7 5.1 2.2 1 0 0 1 1 1 1 Fibronectin type II domain PRKCSH_1 PF13015.1 KFM00517.1 - 1e-08 34.8 43.8 0.0075 15.7 0.2 10.2 10 1 1 11 11 11 6 Glucosidase II beta subunit-like protein DUF4448 PF14610.1 KFM00517.1 - 0.0028 17.1 1.5 6.4 6.2 0.0 3.9 4 0 0 4 4 4 2 Protein of unknown function (DUF4448) Sugar_tr PF00083.19 KFM00518.1 - 1.8e-36 125.6 7.4 2.3e-36 125.3 5.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFM00518.1 - 8e-26 90.5 12.4 8e-26 90.5 8.6 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFM00520.1 - 6.7e-36 123.8 3.5 8.9e-36 123.4 2.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFM00520.1 - 1.4e-27 96.3 26.2 1.3e-25 89.8 10.5 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFM00521.1 - 6.6e-28 97.4 16.3 6.6e-28 97.4 11.3 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 KFM00521.1 - 5.2e-27 94.4 34.6 7.6e-21 74.1 11.0 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Cytochrom_B558a PF05038.8 KFM00521.1 - 0.097 12.2 0.3 0.44 10.1 0.1 2.2 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit P5-ATPase PF12409.3 KFM00521.1 - 1.7 8.5 5.4 2 8.2 0.8 2.7 2 0 0 2 2 2 0 P5-type ATPase cation transporter Kringle PF00051.13 KFM00522.1 - 3.5e-148 482.0 72.1 8.5e-31 105.8 5.8 5.5 5 0 0 5 5 5 5 Kringle domain Trypsin PF00089.21 KFM00522.1 - 2.4e-63 213.6 0.1 3.9e-63 212.9 0.1 1.4 1 0 0 1 1 1 1 Trypsin PAN_1 PF00024.21 KFM00522.1 - 9.3e-10 38.1 2.1 9.3e-10 38.1 1.4 2.4 2 0 0 2 2 2 1 PAN domain DUF1986 PF09342.6 KFM00522.1 - 6.7e-09 35.4 0.0 1.4e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 KFM00522.1 - 6.3e-05 22.9 0.0 0.00014 21.8 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain KduI PF04962.7 KFM00522.1 - 0.14 11.1 7.1 3.5 6.6 0.0 3.3 3 0 0 3 3 3 0 KduI/IolB family Kringle PF00051.13 KFM00523.1 - 8.2e-143 464.8 65.7 1.1e-30 105.5 4.7 5.5 5 0 0 5 5 5 5 Kringle domain Trypsin PF00089.21 KFM00523.1 - 8e-48 162.9 0.1 1.5e-47 162.0 0.1 1.5 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 KFM00523.1 - 2.4e-11 43.4 0.1 5.8e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) PAN_1 PF00024.21 KFM00523.1 - 5.7e-07 29.2 1.1 5.7e-07 29.2 0.8 2.9 4 0 0 4 4 4 1 PAN domain DUF3719 PF12516.3 KFM00523.1 - 6.4 6.4 15.9 24 4.5 0.1 5.2 5 0 0 5 5 5 0 Protein of unknown function (DUF3719) Pkinase PF00069.20 KFM00524.1 - 2e-66 223.8 0.0 4.6e-66 222.6 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM00524.1 - 4.9e-42 143.7 0.0 1.1e-41 142.6 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM00524.1 - 4.9e-08 32.2 0.0 1.2e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KFM00524.1 - 0.0053 16.1 0.1 0.091 12.0 0.0 2.9 2 1 1 3 3 3 1 RIO1 family LOH1CR12 PF10158.4 KFM00524.1 - 1.9 8.3 10.6 0.96 9.2 0.1 3.4 4 0 0 4 4 4 0 Tumour suppressor protein Acyltransferase PF01553.16 KFM00525.1 - 1.5e-14 53.5 0.0 2.7e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Metallophos PF00149.23 KFM00528.1 - 5.2e-15 55.3 0.1 9.2e-15 54.5 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KFM00528.1 - 1.7e-08 34.4 0.0 2.7e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_35 PF01301.14 KFM00529.1 - 1.5e-106 356.3 0.0 6.3e-106 354.3 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.10 KFM00529.1 - 2.2e-13 50.0 0.0 1.1e-08 34.5 0.0 2.2 1 1 1 2 2 2 2 Beta-galactosidase BetaGal_dom4_5 PF13364.1 KFM00529.1 - 7.8e-07 29.3 0.2 0.0001 22.5 0.0 3.1 3 0 0 3 3 3 1 Beta-galactosidase jelly roll domain 7tm_1 PF00001.16 KFM00530.1 - 2.5e-56 190.6 23.6 3.3e-56 190.3 16.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM00530.1 - 1.6e-10 40.6 24.6 2.2e-10 40.1 17.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 60KD_IMP PF02096.15 KFM00530.1 - 0.15 11.7 10.2 0.51 9.9 7.1 1.8 1 1 0 1 1 1 0 60Kd inner membrane protein 7tm_1 PF00001.16 KFM00531.1 - 8.7e-56 188.9 20.7 1.1e-55 188.6 14.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM00531.1 - 7e-09 35.2 21.4 7e-09 35.2 14.9 1.4 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 60KD_IMP PF02096.15 KFM00531.1 - 0.47 10.0 5.4 0.68 9.5 3.8 1.4 1 1 0 1 1 1 0 60Kd inner membrane protein Mito_carr PF00153.22 KFM00532.1 - 1.3e-60 201.0 8.5 1.4e-19 69.5 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein TRAPP PF04051.11 KFM00532.1 - 0.12 11.8 0.0 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 Transport protein particle (TRAPP) component Ribosomal_S2 PF00318.15 KFM00533.1 - 3.7e-43 147.1 0.0 1.1e-39 135.8 0.0 2.1 1 1 0 1 1 1 1 Ribosomal protein S2 TAT_signal PF10518.4 KFM00533.1 - 1.3 9.2 6.7 0.71 10.0 1.6 2.3 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence TMC PF07810.8 KFM00534.1 - 2.7e-38 130.8 2.1 7.2e-38 129.4 1.0 2.2 2 0 0 2 2 2 1 TMC domain Speriolin_N PF15058.1 KFM00534.1 - 0.0058 16.5 0.1 0.01 15.7 0.1 1.3 1 0 0 1 1 1 1 Speriolin N terminus SpoIIIAH PF12685.2 KFM00534.1 - 6.9 6.1 24.2 0.078 12.4 0.4 2.4 2 0 0 2 2 2 0 SpoIIIAH-like protein FYVE_2 PF02318.11 KFM00535.1 - 1.3e-24 86.3 20.5 1.4e-24 86.2 14.2 1.0 1 0 0 1 1 1 1 FYVE-type zinc finger zf-UDP PF14569.1 KFM00535.1 - 0.25 11.1 11.7 0.36 10.6 8.1 1.3 1 1 0 1 1 1 0 Zinc-binding RING-finger Siva PF05458.7 KFM00535.1 - 0.35 10.4 12.1 0.39 10.2 8.4 1.1 1 0 0 1 1 1 0 Cd27 binding protein (Siva) FYVE PF01363.16 KFM00535.1 - 0.77 9.6 23.7 3.2 7.7 16.5 2.1 1 1 0 1 1 1 0 FYVE zinc finger Rab_eff_C PF04698.7 KFM00536.1 - 0 1279.6 24.4 0 1279.4 16.9 1.0 1 0 0 1 1 1 1 Rab effector MyRIP/melanophilin C-terminus SUI1 PF01253.17 KFM00537.1 - 2.3e-30 104.2 2.0 2.6e-30 104.0 1.4 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Mitoc_L55 PF09776.4 KFM00537.1 - 0.11 12.0 0.1 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L55 Gastrin PF00918.12 KFM00538.1 - 4.3e-35 121.0 0.0 5e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 Gastrin/cholecystokinin family HAP1_N PF04849.8 KFM00539.1 - 5.5e-143 475.4 35.6 8.3e-143 474.9 24.7 1.3 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Milton PF12448.3 KFM00539.1 - 1.2e-69 233.6 25.6 1.3e-44 152.2 4.7 3.4 4 0 0 4 4 4 2 Kinesin associated protein MCPsignal PF00015.16 KFM00539.1 - 0.081 12.4 9.1 4 6.9 3.8 2.5 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1664 PF07889.7 KFM00539.1 - 0.082 12.7 17.4 0.046 13.5 1.0 3.8 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) Mod_r PF07200.8 KFM00539.1 - 0.61 9.9 31.9 0.11 12.3 6.7 3.6 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein IncA PF04156.9 KFM00539.1 - 2.6 7.6 43.4 9.4 5.7 14.1 3.3 1 1 2 3 3 3 0 IncA protein DUF4226 PF10774.4 KFM00539.1 - 3.1 7.8 9.3 0.23 11.4 1.8 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4226) Atg14 PF10186.4 KFM00539.1 - 5.3 5.8 31.4 3.2 6.6 2.2 2.3 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF972 PF06156.8 KFM00539.1 - 5.5 7.3 32.2 19 5.6 2.6 4.6 1 1 2 4 4 4 0 Protein of unknown function (DUF972) Arm PF00514.18 KFM00540.1 - 7.8e-57 187.3 21.1 1.9e-08 33.8 0.1 12.5 13 0 0 13 13 13 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFM00540.1 - 2.1e-15 56.7 9.5 6.4e-06 26.3 0.3 5.6 3 2 3 6 6 6 5 HEAT repeats HEAT PF02985.17 KFM00540.1 - 2.2e-09 36.6 3.3 2.7 8.3 0.0 6.2 5 0 0 5 5 5 3 HEAT repeat Adaptin_N PF01602.15 KFM00540.1 - 2.8e-07 29.2 2.5 0.00019 19.8 0.6 3.2 3 0 0 3 3 3 2 Adaptin N terminal region Proteasom_PSMB PF10508.4 KFM00540.1 - 4.1e-05 22.0 5.2 0.0091 14.3 0.7 3.7 2 1 2 4 4 4 2 Proteasome non-ATPase 26S subunit KAP PF05804.7 KFM00540.1 - 5.7e-05 21.2 1.5 0.021 12.7 0.0 3.5 1 1 1 3 3 3 1 Kinesin-associated protein (KAP) Arm_2 PF04826.8 KFM00540.1 - 0.00015 20.9 1.9 0.14 11.2 0.0 4.0 3 1 1 4 4 4 1 Armadillo-like RasGEF_N_2 PF14663.1 KFM00540.1 - 0.0031 17.4 6.7 5.1 7.0 0.1 4.7 6 0 0 6 6 6 2 Rapamycin-insensitive companion of mTOR RasGEF_N domain RIX1 PF08167.7 KFM00540.1 - 0.0033 17.1 0.6 0.29 10.7 0.1 2.7 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis Cnd1 PF12717.2 KFM00540.1 - 0.0056 16.5 0.4 0.28 11.0 0.1 3.2 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 KFM00540.1 - 0.018 15.5 13.8 1.8 9.1 0.1 6.6 7 2 2 9 9 8 0 HEAT-like repeat DUF4604 PF15377.1 KFM00541.1 - 4.7e-30 104.9 14.4 6.7e-30 104.3 10.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Asp-B-Hydro_N PF05279.6 KFM00541.1 - 0.11 12.3 6.6 0.13 12.0 4.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Kinesin PF00225.18 KFM00542.1 - 1.1e-99 333.3 0.0 1.1e-99 333.3 0.0 4.2 2 2 1 3 3 3 1 Kinesin motor domain Kinesin-relat_1 PF12711.2 KFM00542.1 - 8.1e-21 74.2 9.2 8.1e-21 74.2 6.4 13.6 7 6 4 11 11 11 2 Kinesin motor WD40_alt PF14077.1 KFM00542.1 - 3.2 7.4 11.1 0.17 11.5 0.2 4.4 4 0 0 4 4 4 0 Alternative WD40 repeat motif Transglut_N PF00868.15 KFM00543.1 - 1.6e-31 108.7 0.0 4.1e-31 107.4 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase family Transglut_C PF00927.17 KFM00543.1 - 3.4e-19 68.8 0.2 1.7e-12 47.3 0.0 2.6 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.14 KFM00543.1 - 3.4e-14 53.0 0.1 8.2e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily zf-DHHC PF01529.15 KFM00544.1 - 7.5e-40 136.1 10.0 7.5e-40 136.1 6.9 1.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase RNase_PH PF01138.16 KFM00545.1 - 4.7e-24 85.1 0.0 7.6e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KFM00545.1 - 6.8e-10 38.7 1.1 1.1e-09 38.0 0.1 2.0 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Lectin_C PF00059.16 KFM00546.1 - 2.1e-17 63.6 0.1 2.6e-17 63.3 0.1 1.1 1 0 0 1 1 1 1 Lectin C-type domain DUF333 PF03891.10 KFM00546.1 - 4.5e-05 23.1 0.7 0.011 15.4 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF333) Chordopox_A33R PF05966.7 KFM00546.1 - 0.0003 19.6 0.1 0.00039 19.2 0.1 1.2 1 0 0 1 1 1 1 Chordopoxvirus A33R protein CUB PF00431.15 KFM00547.1 - 5.6e-05 23.1 0.0 4.5 7.3 0.0 4.3 4 0 0 4 4 4 3 CUB domain tRNA-synt_1 PF00133.17 KFM00548.1 - 1e-48 165.7 3.8 8.3e-22 76.9 0.2 6.0 2 1 3 5 5 5 4 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KFM00548.1 - 4.7e-32 111.1 0.0 2.1e-21 76.0 0.0 3.5 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KFM00548.1 - 3.5e-11 43.0 0.2 6.6e-11 42.1 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.1 KFM00548.1 - 1.2e-09 37.7 0.0 2e-07 30.4 0.0 2.5 1 1 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 KFM00548.1 - 0.00017 20.8 0.0 0.12 11.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 KFM00548.1 - 0.0015 17.4 0.0 0.0056 15.5 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (R) tRNA-synt_1f PF01921.13 KFM00548.1 - 0.0072 15.0 0.0 0.39 9.3 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (K) LIM PF00412.17 KFM00549.1 - 1.8e-32 111.1 34.5 3e-12 46.4 4.2 3.3 3 0 0 3 3 3 3 LIM domain DUF416 PF04222.7 KFM00549.1 - 0.17 11.0 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF416) Mut7-C PF01927.11 KFM00549.1 - 2.2 8.2 12.5 24 4.8 0.1 3.4 2 1 0 2 2 2 0 Mut7-C RNAse domain Syja_N PF02383.13 KFM00550.1 - 8.3e-94 313.9 0.7 1.2e-93 313.4 0.5 1.2 1 0 0 1 1 1 1 SacI homology domain LSM PF01423.17 KFM00551.1 - 1.2e-18 66.4 0.7 1.9e-18 65.7 0.5 1.3 1 0 0 1 1 1 1 LSM domain Gemin7 PF11095.3 KFM00551.1 - 0.022 14.4 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) LRR_1 PF00560.28 KFM00551.1 - 0.082 12.9 0.1 0.22 11.6 0.1 1.7 2 0 0 2 2 2 0 Leucine Rich Repeat SM-ATX PF14438.1 KFM00551.1 - 0.085 12.7 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain API5 PF05918.6 KFM00551.1 - 1.1 7.6 10.1 0.18 10.2 4.4 1.5 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) SNF PF00209.13 KFM00552.1 - 2e-174 580.9 30.1 2.5e-174 580.6 20.9 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Leu_zip PF15294.1 KFM00553.1 - 1.1e-120 401.9 34.1 1.2e-120 401.8 23.7 1.0 1 0 0 1 1 1 1 Leucine zipper DUF1311 PF07007.7 KFM00553.1 - 0.65 10.1 7.6 0.35 10.9 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1311) HisKA_3 PF07730.8 KFM00553.1 - 0.72 10.2 3.3 21 5.5 0.1 2.9 2 0 0 2 2 2 0 Histidine kinase Spc7 PF08317.6 KFM00553.1 - 6.9 5.2 29.0 0.37 9.4 15.3 2.2 2 1 0 2 2 2 0 Spc7 kinetochore protein Mtp PF03821.11 KFM00554.1 - 3.8e-73 245.7 17.2 8e-71 238.1 11.9 2.0 1 1 0 1 1 1 1 Golgi 4-transmembrane spanning transporter Sigma_reg_N PF13800.1 KFM00554.1 - 0.78 9.8 4.1 2 8.5 0.2 2.8 3 0 0 3 3 3 0 Sigma factor regulator N-terminal NfeD PF01957.13 KFM00554.1 - 3.2 7.8 6.2 0.69 10.0 1.1 2.0 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding VWA PF00092.23 KFM00555.1 - 1.1e-45 155.5 0.1 1.4e-45 155.1 0.1 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain FXa_inhibition PF14670.1 KFM00555.1 - 2.1e-30 104.5 61.8 5.5e-08 32.7 6.8 4.3 4 0 0 4 4 4 4 Coagulation Factor Xa inhibitory site cEGF PF12662.2 KFM00555.1 - 1e-21 76.2 31.2 4.5e-06 26.1 0.8 4.8 4 0 0 4 4 4 4 Complement Clr-like EGF-like EGF_CA PF07645.10 KFM00555.1 - 5.6e-20 71.0 50.4 2.7e-06 27.2 4.8 4.3 4 0 0 4 4 4 4 Calcium-binding EGF domain VWA_2 PF13519.1 KFM00555.1 - 5.8e-17 62.3 0.0 6.4e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain EGF PF00008.22 KFM00555.1 - 2.3e-07 30.6 48.3 0.049 13.6 3.5 4.4 4 0 0 4 4 4 4 EGF-like domain ANATO PF01821.13 KFM00555.1 - 8.7e-06 25.7 18.5 0.69 10.0 0.2 5.9 4 3 1 5 5 5 4 Anaphylotoxin-like domain VWA_3 PF13768.1 KFM00555.1 - 0.00031 20.4 0.1 0.00044 19.9 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 KFM00555.1 - 0.0086 15.9 0.1 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus EGF_3 PF12947.2 KFM00555.1 - 0.017 15.0 46.4 0.087 12.8 4.4 4.7 4 0 0 4 4 4 0 EGF domain DUF4215 PF13948.1 KFM00555.1 - 1.1 9.5 44.1 2.8 8.2 1.0 5.2 3 1 2 5 5 5 0 Domain of unknown function (DUF4215) WD40 PF00400.27 KFM00556.1 - 1.4e-10 40.6 7.8 0.02 14.8 0.0 6.9 7 0 0 7 7 7 3 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KFM00556.1 - 3.6e-05 22.7 4.8 0.00051 18.9 0.1 3.9 4 0 0 4 4 4 1 Coatomer WD associated region Clathrin PF00637.15 KFM00556.1 - 0.00022 20.8 4.3 0.00045 19.8 1.3 2.5 1 1 1 2 2 2 1 Region in Clathrin and VPS eIF2A PF08662.6 KFM00556.1 - 0.0021 17.8 0.7 0.036 13.7 0.3 2.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A TPR_1 PF00515.23 KFM00557.1 - 6e-06 25.6 0.1 1.9e-05 24.0 0.0 1.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFM00557.1 - 2.5e-05 23.8 0.1 0.00019 21.1 0.0 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 KFM00557.1 - 0.0072 15.9 0.0 0.011 15.3 0.0 1.4 1 1 0 1 1 1 1 TPR repeat Fis1_TPR_C PF14853.1 KFM00557.1 - 0.01 15.7 0.0 0.012 15.4 0.0 1.1 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.1 KFM00557.1 - 0.01 15.5 0.0 0.037 13.8 0.0 1.8 1 1 1 2 2 2 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 KFM00557.1 - 0.015 14.5 0.4 0.22 10.8 0.0 2.2 1 1 1 2 2 2 0 SHNi-TPR TPR_9 PF13371.1 KFM00557.1 - 0.016 15.0 0.0 0.017 14.9 0.0 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFM00557.1 - 0.021 15.1 0.0 0.022 15.0 0.0 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFM00557.1 - 0.036 14.7 0.0 0.037 14.7 0.0 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFM00557.1 - 0.056 14.1 0.0 0.072 13.7 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat Zona_pellucida PF00100.18 KFM00558.1 - 7.9e-28 97.6 0.1 7.9e-28 97.6 0.0 3.0 3 1 0 3 3 3 1 Zona pellucida-like domain zf-H2C2_2 PF13465.1 KFM00559.1 - 3.2e-14 52.3 22.3 2.5e-07 30.6 0.7 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFM00559.1 - 2.4e-13 49.5 24.7 8.9e-05 22.6 2.3 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM00559.1 - 4.2e-05 23.5 21.4 0.0044 17.2 2.2 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM00559.1 - 0.00062 19.5 18.0 0.0024 17.6 0.9 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM00559.1 - 0.00062 19.8 15.5 0.02 15.0 1.0 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding C1_4 PF07975.7 KFM00559.1 - 0.0013 18.6 11.1 0.18 11.8 4.1 2.7 1 1 2 3 3 3 2 TFIIH C1-like domain GAGA PF09237.6 KFM00559.1 - 0.026 14.1 2.6 0.1 12.1 0.4 2.4 1 1 1 2 2 2 0 GAGA factor zf-met PF12874.2 KFM00559.1 - 0.042 14.0 13.7 0.072 13.3 0.3 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Rpr2 PF04032.11 KFM00559.1 - 0.064 13.1 0.6 0.064 13.1 0.4 2.1 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Zn_Tnp_IS1595 PF12760.2 KFM00559.1 - 0.071 12.9 8.1 0.53 10.1 1.4 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain CpXC PF14353.1 KFM00559.1 - 0.082 12.8 0.1 0.082 12.8 0.0 2.9 1 1 0 2 2 2 0 CpXC protein zf-CHY PF05495.7 KFM00559.1 - 0.087 12.9 11.5 0.13 12.4 4.9 2.2 1 1 1 2 2 2 0 CHY zinc finger XPA_N PF01286.13 KFM00559.1 - 0.12 12.0 9.2 2.5 7.8 1.0 3.2 3 0 0 3 3 3 0 XPA protein N-terminal DUF2321 PF10083.4 KFM00559.1 - 0.86 9.0 3.1 0.52 9.7 0.6 1.6 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-AN1 PF01428.11 KFM00559.1 - 0.86 9.5 17.7 2.2 8.2 3.3 3.4 2 1 1 3 3 3 0 AN1-like Zinc finger LIM PF00412.17 KFM00559.1 - 0.89 9.6 11.8 8.1 6.5 4.2 2.5 1 1 0 2 2 2 0 LIM domain Zn-ribbon_8 PF09723.5 KFM00559.1 - 0.94 9.4 11.7 7.5 6.5 0.4 3.1 2 1 0 2 2 2 0 Zinc ribbon domain Elf1 PF05129.8 KFM00559.1 - 1.5 8.5 9.9 0.28 10.8 1.2 2.3 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like FYVE PF01363.16 KFM00559.1 - 3 7.8 14.4 1.6 8.7 5.0 2.4 1 1 1 2 2 2 0 FYVE zinc finger DZR PF12773.2 KFM00559.1 - 5.4 6.9 9.0 19 5.1 0.1 2.3 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_5 PF14634.1 KFM00559.1 - 5.9 6.7 8.7 9.7 6.0 3.5 2.3 2 0 0 2 2 2 0 zinc-RING finger domain zf-Di19 PF05605.7 KFM00559.1 - 9.7 6.4 11.7 0.38 10.9 2.9 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding 5-nucleotidase PF06189.7 KFM00560.1 - 9e-103 342.6 0.0 1.1e-102 342.4 0.0 1.0 1 0 0 1 1 1 1 5'-nucleotidase Acid_PPase PF12689.2 KFM00560.1 - 0.083 12.5 0.0 0.27 10.8 0.0 1.8 2 0 0 2 2 2 0 Acid Phosphatase adh_short PF00106.20 KFM00561.1 - 5.6e-05 23.1 0.0 0.00014 21.8 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase Ion_trans PF00520.26 KFM00562.1 - 8.5e-36 123.0 1.0 8.5e-36 123.0 0.7 1.5 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 KFM00562.1 - 8.5e-33 112.4 1.3 3.1e-32 110.6 0.1 2.4 3 0 0 3 3 3 1 BTB/POZ domain Ion_trans_2 PF07885.11 KFM00562.1 - 1.3e-11 44.0 4.0 1.3e-11 44.0 2.8 1.9 2 0 0 2 2 2 1 Ion channel PKD_channel PF08016.7 KFM00562.1 - 0.00091 17.7 1.3 0.0013 17.2 0.9 1.2 1 0 0 1 1 1 1 Polycystin cation channel Zona_pellucida PF00100.18 KFM00563.1 - 2.9e-39 135.0 2.9 3.6e-37 128.2 0.5 2.7 3 0 0 3 3 3 2 Zona pellucida-like domain HLH PF00010.21 KFM00564.1 - 1.3e-12 47.2 2.2 1.9e-12 46.6 0.9 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain XPG_I PF00867.13 KFM00565.1 - 2.3e-25 88.4 1.1 4.8e-25 87.4 0.1 2.1 2 0 0 2 2 2 1 XPG I-region EF-hand_1 PF00036.27 KFM00566.1 - 4.2e-25 85.0 13.1 2.6e-08 32.5 0.1 4.7 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 KFM00566.1 - 8.5e-23 78.1 4.7 8.1e-07 28.4 0.1 4.7 4 1 1 5 5 5 3 EF-hand domain EF-hand_7 PF13499.1 KFM00566.1 - 6.1e-22 77.5 6.3 3.5e-13 49.4 0.6 3.0 1 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 KFM00566.1 - 6.8e-18 63.1 10.2 1.1e-06 27.6 0.3 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 KFM00566.1 - 1.5e-15 56.4 8.9 1.6e-05 24.3 0.4 4.3 3 2 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFM00566.1 - 1.8e-05 24.7 2.0 0.0042 17.1 0.3 3.2 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFM00566.1 - 0.028 14.1 7.0 8.2 6.2 0.0 3.9 2 1 2 4 4 4 0 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.8 KFM00566.1 - 0.031 13.8 1.9 0.45 10.0 1.3 2.7 1 1 0 1 1 1 0 Caleosin related protein p25-alpha PF05517.7 KFM00566.1 - 0.13 12.4 1.0 0.39 10.9 0.0 2.1 2 1 0 2 2 2 0 p25-alpha EF-hand_10 PF14788.1 KFM00566.1 - 0.44 10.2 5.4 14 5.4 0.0 3.6 4 0 0 4 4 4 0 EF hand zf-CCHH PF10283.4 KFM00567.1 - 4.3e-20 71.2 14.0 3.5e-10 39.5 3.5 2.5 2 0 0 2 2 2 2 Zinc-finger (CX5CX6HX5H) motif HUN PF08729.5 KFM00567.1 - 0.0023 17.7 8.8 0.006 16.4 6.1 1.7 1 0 0 1 1 1 1 HPC2 and ubinuclein domain SsgA PF04686.7 KFM00567.1 - 0.025 14.2 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 Streptomyces sporulation and cell division protein, SsgA F-box-like PF12937.2 KFM00568.1 - 6.1e-14 51.4 1.0 6.1e-14 51.4 0.7 1.7 1 1 1 2 2 2 1 F-box-like F-box PF00646.28 KFM00568.1 - 3.1e-06 26.6 3.7 3.6e-06 26.4 0.5 2.5 2 1 1 3 3 3 1 F-box domain PH PF00169.24 KFM00569.1 - 1.7e-33 114.8 0.0 1.3e-16 60.6 0.0 2.7 3 0 0 3 3 3 2 PH domain DEP PF00610.16 KFM00569.1 - 2.8e-14 52.5 0.0 5.1e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_9 PF15410.1 KFM00569.1 - 5.4e-11 42.6 0.4 5.1e-05 23.4 0.0 2.7 2 1 0 2 2 2 2 Pleckstrin homology domain PH_6 PF15406.1 KFM00569.1 - 8.4e-10 38.7 0.0 3.6e-06 26.9 0.0 2.4 2 0 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.1 KFM00569.1 - 1e-07 32.1 3.6 0.022 15.0 0.6 4.1 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 KFM00569.1 - 0.00037 20.4 0.2 0.017 15.1 0.0 3.2 2 2 1 3 3 3 1 Pleckstrin homology domain EF-hand_1 PF00036.27 KFM00570.1 - 1.2e-27 93.0 14.2 1.4e-06 27.1 0.4 4.9 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.1 KFM00570.1 - 2.9e-27 94.5 2.9 7.5e-14 51.6 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KFM00570.1 - 3e-22 76.4 5.8 7.9e-06 25.3 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KFM00570.1 - 5.4e-21 72.9 13.6 4.1e-05 22.7 0.2 4.7 4 1 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 KFM00570.1 - 1.9e-20 72.1 7.7 0.00011 21.7 0.1 4.5 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFM00570.1 - 2.3e-08 34.0 0.1 0.00052 20.0 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFM00570.1 - 1.5e-07 31.0 4.6 0.0062 16.2 0.1 3.7 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KFM00570.1 - 0.00055 19.7 0.2 0.059 13.2 0.0 2.7 2 1 1 3 3 3 1 EF-hand domain Caleosin PF05042.8 KFM00570.1 - 0.042 13.3 0.3 3.3 7.2 0.0 2.3 1 1 1 2 2 2 0 Caleosin related protein OST-HTH PF12872.2 KFM00570.1 - 0.098 12.5 0.1 1.6 8.5 0.1 2.7 3 1 0 3 3 3 0 OST-HTH/LOTUS domain KH_1 PF00013.24 KFM00571.1 - 6.1e-07 28.9 1.2 1.5e-06 27.7 0.8 1.6 1 0 0 1 1 1 1 KH domain WD40 PF00400.27 KFM00572.1 - 4.5e-17 61.2 1.9 4.6e-06 26.3 0.0 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 KFM00572.1 - 0.0072 16.0 0.1 0.14 11.9 0.0 2.6 2 1 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.6 KFM00572.1 - 0.029 14.0 0.1 12 5.5 0.0 3.0 3 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Sas10_Utp3 PF04000.10 KFM00573.1 - 1e-18 67.2 0.6 1.5e-18 66.7 0.4 1.3 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Herpes_V23 PF01802.12 KFM00573.1 - 0.009 15.0 0.1 0.011 14.7 0.1 1.1 1 0 0 1 1 1 1 Herpesvirus VP23 like capsid protein SF-assemblin PF06705.6 KFM00573.1 - 0.01 14.9 0.1 0.013 14.7 0.1 1.1 1 0 0 1 1 1 0 SF-assemblin/beta giardin DUF932 PF06067.6 KFM00573.1 - 0.029 13.6 0.1 0.047 12.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF932) ERp29 PF07749.7 KFM00573.1 - 0.091 13.4 0.5 0.16 12.6 0.3 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain ETAA1 PF15350.1 KFM00574.1 - 4.7e-138 461.5 36.2 6.8e-97 325.4 6.9 2.0 1 1 1 2 2 2 2 Ewing's tumour-associated antigen 1 homologue Homeobox_KN PF05920.6 KFM00575.1 - 1e-20 73.1 0.6 2e-20 72.2 0.4 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KFM00575.1 - 1.4e-08 34.2 0.3 3.3e-08 33.0 0.2 1.6 1 0 0 1 1 1 1 Homeobox domain Sprouty PF05210.8 KFM00576.1 - 1.2e-39 134.6 27.4 1.2e-39 134.6 19.0 1.9 2 0 0 2 2 2 1 Sprouty protein (Spry) WH1 PF00568.18 KFM00576.1 - 2.1e-10 40.3 0.0 3.4e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 WH1 domain Actin PF00022.14 KFM00577.1 - 1.1e-115 386.2 0.0 1.2e-115 386.0 0.0 1.0 1 0 0 1 1 1 1 Actin Ras PF00071.17 KFM00578.1 - 1.4e-67 226.1 1.1 1.6e-67 225.9 0.7 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM00578.1 - 1.8e-23 83.2 0.0 2.7e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM00578.1 - 1.6e-17 63.3 0.2 1.9e-17 63.0 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFM00578.1 - 4.2e-07 29.3 0.1 4.8e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFM00578.1 - 2.6e-06 27.0 0.2 5.8e-06 25.8 0.1 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFM00578.1 - 7.5e-06 25.8 0.1 1.5e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KFM00578.1 - 1.2e-05 24.6 0.1 1.8e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.24 KFM00578.1 - 0.00051 20.2 0.0 0.076 13.2 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFM00578.1 - 0.00061 19.9 0.0 0.00095 19.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 KFM00578.1 - 0.0022 17.3 0.0 0.012 14.8 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 KFM00578.1 - 0.0059 15.7 0.1 0.021 13.9 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 KFM00578.1 - 0.017 14.6 0.1 0.86 9.0 0.0 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 KFM00578.1 - 0.033 14.1 0.1 0.092 12.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 KFM00578.1 - 0.046 14.0 0.0 0.065 13.5 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.9 KFM00578.1 - 0.049 13.3 0.0 0.068 12.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 KFM00578.1 - 0.05 13.1 0.1 0.13 11.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.13 KFM00578.1 - 0.069 12.1 0.0 0.15 11.0 0.0 1.6 1 0 0 1 1 1 0 Septin G-alpha PF00503.15 KFM00578.1 - 1.1 7.9 5.9 5.8 5.4 0.7 2.8 1 1 1 2 2 2 0 G-protein alpha subunit Umbravirus_LDM PF04817.7 KFM00580.1 - 1 8.4 10.2 1.3 8.0 7.1 1.3 1 1 0 1 1 1 0 Umbravirus long distance movement (LDM) family SDF PF00375.13 KFM00581.1 - 2e-95 319.8 15.0 2.3e-95 319.6 10.4 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family SERTA PF06031.8 KFM00582.1 - 6.3e-17 60.5 1.3 1e-16 59.9 0.9 1.3 1 0 0 1 1 1 1 SERTA motif Clathrin_bdg PF15045.1 KFM00583.1 - 2.4e-33 113.4 0.0 7.2e-33 111.9 0.0 1.9 1 0 0 1 1 1 1 Clathrin-binding box of Aftiphilin, vesicle trafficking Gal-bind_lectin PF00337.17 KFM00584.1 - 6.7e-30 103.1 0.0 7.3e-30 103.0 0.0 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin HEAT_2 PF13646.1 KFM00585.1 - 1.1e-12 48.0 0.2 1.1 9.5 0.0 7.7 5 3 3 8 8 8 4 HEAT repeats HEAT PF02985.17 KFM00585.1 - 7.8e-10 37.9 0.2 9.9 6.5 0.0 9.3 8 0 0 8 8 8 1 HEAT repeat HEAT_EZ PF13513.1 KFM00585.1 - 1.6e-06 28.3 4.5 0.95 10.0 0.0 8.1 7 1 1 8 8 8 1 HEAT-like repeat ParcG PF10274.4 KFM00585.1 - 7.2e-05 22.7 3.4 0.3 10.9 0.0 4.8 6 0 0 6 6 6 2 Parkin co-regulated protein Vac14_Fab1_bd PF12755.2 KFM00585.1 - 0.04 14.2 0.0 11 6.5 0.0 4.4 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region UME PF08064.8 KFM00585.1 - 0.12 12.3 0.0 0.12 12.3 0.0 5.0 5 0 0 5 5 5 0 UME (NUC010) domain DUF2411 PF10304.4 KFM00585.1 - 2 8.0 7.3 0.27 10.8 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF2411) BOP1NT PF08145.7 KFM00586.1 - 7.6e-110 366.7 7.2 1.1e-109 366.2 5.0 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 KFM00586.1 - 1.8e-37 125.8 12.8 9.4e-13 47.5 0.3 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat HSF_DNA-bind PF00447.12 KFM00587.1 - 1.3e-28 99.2 1.3 1.9e-28 98.6 0.9 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding DUF2365 PF10157.4 KFM00587.1 - 0.035 13.9 0.1 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) Pkinase PF00069.20 KFM00588.1 - 4.3e-58 196.5 0.1 4.7e-58 196.3 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM00588.1 - 1.1e-21 77.0 0.0 1.4e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFM00588.1 - 2.4e-08 34.0 0.0 1.5e-05 24.8 0.1 2.2 1 1 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFM00588.1 - 0.0019 17.8 0.7 0.0041 16.7 0.1 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.9 KFM00588.1 - 0.0024 16.9 0.0 0.004 16.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KFM00588.1 - 0.038 12.9 0.0 0.14 11.0 0.0 1.8 2 0 0 2 2 2 0 Kinase-like ABC1 PF03109.11 KFM00588.1 - 0.094 12.6 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 ABC1 family DUF1409 PF07197.7 KFM00590.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1409) RVT_1 PF00078.22 KFM00592.1 - 0.011 15.0 0.0 0.027 13.8 0.0 1.5 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Lig_chan PF00060.21 KFM00593.1 - 1.4e-44 151.3 0.3 2.3e-44 150.6 0.2 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.15 KFM00593.1 - 2.4e-27 95.6 0.0 3.8e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.4 KFM00593.1 - 2.2e-23 81.9 0.1 5.1e-23 80.8 0.1 1.7 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site ANF_receptor PF01094.23 KFM00593.1 - 5.3e-15 55.0 0.0 9.5e-15 54.2 0.0 1.5 1 0 0 1 1 1 1 Receptor family ligand binding region DUF1469 PF07332.6 KFM00593.1 - 0.012 15.2 0.3 0.012 15.2 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1469) NADH-u_ox-rdase PF10785.4 KFM00593.1 - 0.02 15.1 0.0 0.047 13.9 0.0 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit WAPL PF07814.8 KFM00594.1 - 3.5e-147 489.8 7.6 6.6e-147 488.9 5.3 1.5 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin 7tm_1 PF00001.16 KFM00595.1 - 2.9e-58 197.0 18.0 3.4e-58 196.7 12.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM00595.1 - 2.4e-14 53.1 18.2 3.2e-14 52.7 12.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM00595.1 - 2.6e-08 33.3 19.0 3.6e-08 32.8 13.2 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.1 KFM00595.1 - 0.0025 17.6 1.4 0.0025 17.6 1.0 2.7 4 0 0 4 4 4 1 Olfactory receptor CcmH PF03918.9 KFM00595.1 - 0.11 11.4 0.0 0.25 10.3 0.0 1.5 1 0 0 1 1 1 0 Cytochrome C biogenesis protein DUF2852 PF11014.3 KFM00595.1 - 1.3 8.9 5.6 8.7 6.3 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) Serpentine_r_xa PF03383.10 KFM00595.1 - 2.4 7.9 13.3 0.53 10.0 4.1 2.9 1 1 2 3 3 3 0 Caenorhabditis serpentine receptor-like protein, class xa LIM PF00412.17 KFM00596.1 - 6.8e-38 128.5 31.2 8.6e-14 51.3 2.8 3.3 3 0 0 3 3 3 3 LIM domain PDZ PF00595.19 KFM00596.1 - 4.9e-08 33.0 0.3 9.7e-08 32.0 0.2 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM00596.1 - 0.00066 19.5 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Pkinase PF00069.20 KFM00597.1 - 8.4e-56 188.9 0.0 1.3e-55 188.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM00597.1 - 2.2e-38 131.8 0.0 3.1e-38 131.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TGF_beta_GS PF08515.7 KFM00597.1 - 2.4e-15 55.5 0.5 4.9e-15 54.5 0.3 1.6 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.18 KFM00597.1 - 3e-13 50.1 10.8 3e-13 50.1 7.5 2.4 2 0 0 2 2 2 1 Activin types I and II receptor domain APH PF01636.18 KFM00597.1 - 0.2 11.3 0.0 0.61 9.7 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family C1q PF00386.16 KFM00598.1 - 1.3e-17 63.9 0.2 2.6e-17 63.0 0.2 1.5 1 0 0 1 1 1 1 C1q domain EMI PF07546.8 KFM00598.1 - 1e-14 54.7 3.0 1.8e-14 53.8 2.1 1.4 1 0 0 1 1 1 1 EMI domain Synuclein PF01387.12 KFM00599.1 - 1.6e-51 173.5 26.1 1.8e-51 173.4 18.1 1.0 1 0 0 1 1 1 1 Synuclein MoaF PF10703.4 KFM00599.1 - 0.057 12.4 1.4 0.058 12.4 1.0 1.1 1 0 0 1 1 1 0 Molybdenum cofactor biosynthesis protein F Apolipoprotein PF01442.13 KFM00599.1 - 0.067 12.6 0.3 0.076 12.5 0.2 1.0 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DSRB PF10781.4 KFM00599.1 - 0.087 12.3 0.4 0.51 9.8 0.1 2.3 1 1 1 2 2 2 0 Dextransucrase DSRB EndoU_bacteria PF14436.1 KFM00599.1 - 0.11 12.3 1.4 0.14 12.0 1.0 1.1 1 0 0 1 1 1 0 Bacterial EndoU nuclease Mononeg_mRNAcap PF14318.1 KFM00599.1 - 0.14 11.1 0.1 0.14 11.1 0.1 1.1 1 0 0 1 1 1 0 Mononegavirales mRNA-capping region V YtxH PF12732.2 KFM00599.1 - 4.2 7.7 6.7 20 5.6 4.7 2.0 1 1 0 1 1 1 0 YtxH-like protein ELFV_dehydrog PF00208.16 KFM00600.1 - 7.6e-55 186.1 0.0 4.3e-52 177.1 0.0 2.1 2 0 0 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 KFM00600.1 - 7.7e-34 116.0 0.0 1.4e-33 115.2 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain AlaDh_PNT_C PF01262.16 KFM00600.1 - 0.025 14.1 0.1 0.058 12.9 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 KFM00600.1 - 0.043 12.9 0.0 0.071 12.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SF3b10 PF07189.6 KFM00600.1 - 0.11 12.3 0.0 0.42 10.4 0.0 1.9 2 0 0 2 2 2 0 Splicing factor 3B subunit 10 (SF3b10) C2 PF00168.25 KFM00602.1 - 2.6e-30 104.0 0.9 5.1e-15 55.0 0.1 2.7 3 0 0 3 3 3 2 C2 domain CEP76-C2 PF15627.1 KFM00602.1 - 0.0018 17.7 0.1 0.1 12.1 0.0 3.0 3 0 0 3 3 3 1 CEP76 C2 domain MP PF01107.13 KFM00602.1 - 0.023 14.0 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 Viral movement protein (MP) NT-C2 PF10358.4 KFM00602.1 - 0.085 12.3 1.2 0.99 8.8 0.1 2.3 2 0 0 2 2 2 0 N-terminal C2 in EEIG1 and EHBP1 proteins GRIN_C PF15235.1 KFM00603.1 - 1e-43 148.6 0.8 2.6e-43 147.3 0.0 2.1 2 0 0 2 2 2 1 G protein-regulated inducer of neurite outgrowth C-terminus Tim17 PF02466.14 KFM00604.1 - 2.3e-18 66.4 2.0 2.5e-18 66.3 1.4 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family F5_F8_type_C PF00754.20 KFM00606.1 - 2.4e-29 101.7 1.8 3.4e-29 101.3 0.3 1.8 2 0 0 2 2 2 1 F5/8 type C domain Laminin_G_2 PF02210.19 KFM00606.1 - 1.3e-26 93.1 0.6 2.1e-26 92.4 0.4 1.4 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.18 KFM00606.1 - 6.6e-15 55.2 0.1 1.1e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain MFS_1 PF07690.11 KFM00608.1 - 2.8e-34 118.3 39.3 9.9e-34 116.5 26.1 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2400 PF09674.5 KFM00609.1 - 0.21 11.2 19.2 1 9.0 2.0 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) AAA_13 PF13166.1 KFM00609.1 - 2.6 6.3 41.3 0.63 8.4 25.0 1.9 1 1 1 2 2 2 0 AAA domain ATG16 PF08614.6 KFM00609.1 - 3.1 7.5 55.6 10 5.8 25.1 3.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Tropomyosin_1 PF12718.2 KFM00609.1 - 5 6.9 57.6 5.6 6.7 26.6 3.5 1 1 1 2 2 2 0 Tropomyosin like DUF3584 PF12128.3 KFM00609.1 - 5.6 4.1 48.0 8.2 3.6 33.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Myosin_tail_1 PF01576.14 KFM00610.1 - 0 1108.6 275.9 0 1088.4 145.4 3.0 1 1 2 3 3 3 3 Myosin tail Myosin_head PF00063.16 KFM00610.1 - 1.7e-268 892.3 0.0 1.7e-268 892.3 0.0 3.6 4 1 0 4 4 4 1 Myosin head (motor domain) Myosin_N PF02736.14 KFM00610.1 - 1.7e-15 56.3 6.6 4e-15 55.2 4.6 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Filament PF00038.16 KFM00610.1 - 0.0019 17.7 234.0 0.0038 16.7 17.5 7.9 1 1 7 8 8 8 4 Intermediate filament protein DUF1664 PF07889.7 KFM00610.1 - 0.0057 16.4 2.9 0.0057 16.4 2.0 12.9 4 2 9 13 13 13 4 Protein of unknown function (DUF1664) Reo_sigmaC PF04582.7 KFM00610.1 - 0.0077 15.4 76.5 0.28 10.3 1.6 9.0 1 1 7 10 10 10 5 Reovirus sigma C capsid protein IQ PF00612.22 KFM00610.1 - 0.03 13.9 3.5 1.1 9.0 0.5 3.0 2 0 0 2 2 2 0 IQ calmodulin-binding motif AAA_19 PF13245.1 KFM00610.1 - 0.035 13.8 0.0 0.12 12.1 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 KFM00610.1 - 0.081 13.0 0.0 0.081 13.0 0.0 5.6 5 3 0 5 5 5 0 AAA domain V-set PF07686.12 KFM00611.1 - 6e-20 71.2 8.8 9.8e-11 41.5 0.1 3.0 2 1 2 4 4 4 2 Immunoglobulin V-set domain I-set PF07679.11 KFM00611.1 - 5.6e-15 54.9 1.0 7.8e-05 22.4 0.0 3.2 2 1 1 3 3 3 3 Immunoglobulin I-set domain ig PF00047.20 KFM00611.1 - 2.6e-10 40.2 8.8 0.0043 17.1 0.2 4.9 3 2 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.1 KFM00611.1 - 3e-09 36.8 11.2 0.00041 20.4 0.1 3.3 2 1 1 3 3 3 3 Immunoglobulin domain V-set_CD47 PF08204.6 KFM00611.1 - 3.8e-07 29.9 0.9 0.0078 15.9 0.0 2.3 2 0 0 2 2 2 2 CD47 immunoglobulin-like domain Ig_3 PF13927.1 KFM00611.1 - 0.00024 21.5 15.8 0.31 11.5 1.7 3.7 2 1 1 3 3 3 3 Immunoglobulin domain C2-set_2 PF08205.7 KFM00611.1 - 0.00047 19.9 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain IFT57 PF10498.4 KFM00612.1 - 6.3e-128 426.5 6.0 7.2e-128 426.3 4.2 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Halogen_Hydrol PF10112.4 KFM00612.1 - 0.0049 16.2 1.0 1.4 8.2 0.0 2.6 1 1 1 2 2 2 2 5-bromo-4-chloroindolyl phosphate hydrolysis protein UBN2_3 PF14244.1 KFM00612.1 - 0.0049 16.4 1.6 0.01 15.4 1.1 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Ribonuc_L-PSP PF01042.16 KFM00612.1 - 0.0064 16.2 0.5 0.059 13.1 0.0 2.4 2 0 0 2 2 2 1 Endoribonuclease L-PSP IMD PF08397.6 KFM00612.1 - 0.012 14.8 7.6 0.023 14.0 5.3 1.5 1 1 0 1 1 1 0 IRSp53/MIM homology domain Bacillus_HBL PF05791.6 KFM00612.1 - 0.017 14.5 0.4 0.017 14.5 0.2 3.0 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) BCNT PF07572.7 KFM00612.1 - 0.035 14.0 0.7 0.21 11.5 0.1 2.4 2 0 0 2 2 2 0 Bucentaur or craniofacial development LMF1 PF06762.9 KFM00612.1 - 0.11 11.2 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Lipase maturation factor CENP-Q PF13094.1 KFM00612.1 - 1.4 8.9 20.9 0.4 10.7 4.5 2.3 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit CD47 PF04549.9 KFM00613.1 - 2.7e-39 134.7 14.6 3.7e-39 134.2 10.1 1.2 1 0 0 1 1 1 1 CD47 transmembrane region V-set_CD47 PF08204.6 KFM00613.1 - 1.9e-35 121.4 0.0 2.7e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 CD47 immunoglobulin-like domain V-set PF07686.12 KFM00613.1 - 0.00062 19.6 0.0 0.00098 18.9 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 KFM00613.1 - 0.0027 17.7 0.0 0.0047 17.0 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 KFM00613.1 - 0.0062 16.3 0.0 0.012 15.4 0.0 1.4 1 1 0 1 1 1 1 Immunoglobulin I-set domain Pox_I5 PF04713.7 KFM00613.1 - 0.047 13.4 1.2 0.047 13.4 0.8 2.7 3 0 0 3 3 3 0 Poxvirus protein I5 DUF2028 PF09667.5 KFM00614.1 - 3.7e-51 173.2 5.2 3.7e-51 173.2 3.6 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF2028) HMG_box PF00505.14 KFM00614.1 - 7.8e-17 61.3 0.9 7.8e-17 61.3 0.6 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFM00614.1 - 4.3e-10 39.8 1.0 4.3e-10 39.8 0.7 2.2 2 0 0 2 2 2 1 HMG-box domain Cbl_N PF02262.11 KFM00616.1 - 7.4e-56 187.4 1.4 1.5e-55 186.4 1.0 1.5 1 0 0 1 1 1 1 CBL proto-oncogene N-terminal domain 1 Cbl_N3 PF02762.9 KFM00616.1 - 1e-51 172.4 0.1 2.5e-51 171.2 0.0 1.7 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, SH2-like domain Cbl_N2 PF02761.9 KFM00616.1 - 1.9e-45 152.7 1.4 3.3e-45 152.0 1.0 1.4 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain zf-C3HC4_3 PF13920.1 KFM00616.1 - 2.8e-10 39.7 7.7 5.5e-10 38.7 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM00616.1 - 9.6e-09 35.1 7.4 2.5e-08 33.7 5.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM00616.1 - 1.2e-08 34.4 7.4 1.2e-08 34.4 5.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM00616.1 - 3.3e-06 26.8 6.8 1e-05 25.2 4.7 1.9 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.1 KFM00616.1 - 1.3e-05 24.5 5.0 2.9e-05 23.5 3.4 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.1 KFM00616.1 - 0.00014 21.5 10.2 0.00036 20.2 7.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFM00616.1 - 0.0083 15.9 8.2 0.025 14.4 5.7 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DUF2205 PF10224.4 KFM00616.1 - 0.12 11.9 0.2 0.26 10.8 0.1 1.5 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) zf-RING_UBOX PF13445.1 KFM00616.1 - 0.43 10.3 7.1 1.7 8.4 4.9 2.1 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 KFM00616.1 - 5.1 6.7 18.6 0.052 13.1 6.9 2.3 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain C2-set_2 PF08205.7 KFM00617.1 - 1.2e-26 92.4 7.6 1.9e-20 72.5 0.0 4.6 3 1 1 4 4 4 2 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.1 KFM00617.1 - 1.6e-25 89.0 10.2 9.3e-07 28.8 0.1 5.6 5 1 0 5 5 5 4 Immunoglobulin domain Ig_3 PF13927.1 KFM00617.1 - 1.1e-17 64.3 15.5 8.9e-06 26.1 0.0 6.3 5 2 1 6 6 6 5 Immunoglobulin domain I-set PF07679.11 KFM00617.1 - 6.6e-15 54.7 16.8 0.0025 17.6 0.1 7.9 5 3 0 6 6 6 6 Immunoglobulin I-set domain V-set PF07686.12 KFM00617.1 - 3.4e-13 49.4 12.2 5.3e-05 23.0 0.0 7.5 5 4 1 6 6 6 3 Immunoglobulin V-set domain ig PF00047.20 KFM00617.1 - 2e-11 43.8 12.8 0.0045 17.0 0.1 7.3 6 2 0 6 6 6 4 Immunoglobulin domain C1-set PF07654.10 KFM00617.1 - 1.5e-07 31.3 10.8 0.0014 18.5 0.1 4.9 5 1 0 5 5 5 2 Immunoglobulin C1-set domain DUF4366 PF14283.1 KFM00617.1 - 0.0014 18.0 0.1 0.0025 17.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) DUF2924 PF11149.3 KFM00619.1 - 4.9 7.1 9.9 85 3.1 6.8 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2924) LRR_4 PF12799.2 KFM00620.1 - 1.1e-27 95.0 42.8 1.9e-08 33.7 1.0 5.3 3 2 4 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM00620.1 - 2.4e-24 84.8 11.4 5e-09 35.7 1.1 4.0 2 2 2 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 KFM00620.1 - 1.7e-16 57.6 18.8 0.0028 17.4 0.1 7.3 7 0 0 7 7 7 5 Leucine Rich Repeat LRR_7 PF13504.1 KFM00620.1 - 3.1e-11 41.5 13.9 0.52 10.7 0.2 7.3 7 0 0 7 7 7 4 Leucine rich repeat LRR_6 PF13516.1 KFM00620.1 - 3.1e-08 32.8 15.4 0.1 12.7 0.2 6.3 6 0 0 6 6 6 3 Leucine Rich repeat CFC PF09443.5 KFM00621.1 - 7e-15 54.3 9.5 7e-15 54.3 6.6 2.4 2 0 0 2 2 2 1 Cripto_Frl-1_Cryptic (CFC) EGF PF00008.22 KFM00621.1 - 0.014 15.3 7.8 0.047 13.6 5.4 1.9 1 0 0 1 1 1 0 EGF-like domain Lipoprotein_20 PF13942.1 KFM00622.1 - 0.016 14.7 1.7 0.018 14.6 1.2 1.0 1 0 0 1 1 1 0 YfhG lipoprotein DUF3350 PF11830.3 KFM00622.1 - 0.018 15.0 1.3 0.018 15.0 0.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3350) DUF2407_C PF13373.1 KFM00622.1 - 0.12 12.3 1.5 0.13 12.2 1.0 1.1 1 0 0 1 1 1 0 DUF2407 C-terminal domain MIT PF04212.13 KFM00622.1 - 0.12 12.2 1.5 0.14 12.0 1.0 1.1 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain AhpC-TSA_2 PF13911.1 KFM00623.1 - 1.7e-20 73.0 0.0 2e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.5 KFM00623.1 - 0.0019 17.7 0.0 0.0028 17.2 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KFM00623.1 - 0.0027 17.4 0.0 0.0036 16.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family DUF899 PF05988.7 KFM00623.1 - 0.034 13.6 0.0 0.042 13.2 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) DSPn PF14671.1 KFM00624.1 - 9.2e-57 190.9 3.1 1.1e-55 187.4 1.2 2.3 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 KFM00624.1 - 2.2e-15 56.3 0.0 4.7e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFM00624.1 - 5.1e-06 25.9 0.1 1.5e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KFM00624.1 - 3.2e-05 24.0 0.0 5.8e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 KFM00624.1 - 0.0021 18.3 0.0 0.0044 17.2 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 KFM00624.1 - 0.043 13.1 0.0 0.088 12.1 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family HABP4_PAI-RBP1 PF04774.10 KFM00625.1 - 1e-11 45.2 4.5 1e-11 45.2 3.1 3.1 3 1 1 4 4 4 2 Hyaluronan / mRNA binding family zf-H2C2_2 PF13465.1 KFM00626.1 - 5e-16 58.1 7.8 1.1e-07 31.7 0.1 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFM00626.1 - 1e-09 38.1 11.9 6.1e-05 23.1 0.4 3.3 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM00626.1 - 7e-07 29.1 13.5 0.0002 21.4 0.7 3.5 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM00626.1 - 8e-06 25.5 0.7 0.00012 21.8 0.2 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.2 KFM00626.1 - 0.00014 21.9 0.7 0.00064 19.8 0.1 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFM00626.1 - 0.00014 21.8 0.3 0.0018 18.3 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Phage_GPD PF05954.6 KFM00626.1 - 0.006 15.8 2.0 0.0086 15.2 1.4 1.2 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) MotA_ExbB PF01618.11 KFM00626.1 - 0.41 10.2 2.2 0.74 9.4 0.4 1.9 1 1 1 2 2 2 0 MotA/TolQ/ExbB proton channel family PBP1_TM PF14812.1 KFM00626.1 - 1.3 9.3 5.7 0.36 11.1 1.8 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TPT PF03151.11 KFM00627.1 - 9.3e-11 41.6 8.7 9.3e-11 41.6 6.0 2.4 2 1 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 KFM00627.1 - 2.2e-05 23.5 13.4 3.1e-05 23.0 9.3 1.3 1 0 0 1 1 1 1 UAA transporter family VIGSSK PF14773.1 KFM00628.1 - 3.9e-08 33.0 0.1 1.2e-07 31.4 0.1 1.9 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal SNF2_N PF00176.18 KFM00629.1 - 2.6e-57 193.9 0.4 3.6e-57 193.4 0.3 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFM00629.1 - 2.1e-16 59.5 0.2 2.7e-15 55.9 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KFM00629.1 - 2.6e-08 33.0 0.2 8.7e-08 31.3 0.1 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 KFM00629.1 - 4.6e-08 32.7 0.0 1.2e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 KFM00629.1 - 2.9e-07 30.5 0.1 8.8e-07 28.9 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SMN PF06003.7 KFM00629.1 - 0.028 13.5 0.0 0.054 12.6 0.0 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) SEC-C PF02810.10 KFM00629.1 - 0.064 12.8 7.2 0.16 11.5 5.0 1.7 1 0 0 1 1 1 0 SEC-C motif HTH_29 PF13551.1 KFM00629.1 - 0.069 13.2 0.0 25 5.0 0.0 3.0 3 0 0 3 3 3 0 Winged helix-turn helix Yae1_N PF09811.4 KFM00630.1 - 3.5e-10 39.2 26.1 0.062 12.8 18.1 3.0 1 1 0 1 1 1 1 Essential protein Yae1, N terminal Patched PF02460.13 KFM00631.1 - 4.5e-73 246.4 18.4 6.6e-44 150.0 0.9 2.1 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.3 KFM00631.1 - 2.9e-46 156.7 4.9 2.9e-46 156.7 3.4 2.9 3 1 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation MENTAL PF10457.4 KFM00631.1 - 1.8 8.1 7.1 4.1 6.9 0.2 2.4 2 0 0 2 2 2 0 Cholesterol-capturing domain Fanconi_C PF02106.10 KFM00632.1 - 1.9e-274 911.2 19.6 2.2e-274 911.1 13.6 1.0 1 0 0 1 1 1 1 Fanconi anaemia group C protein Peptidase_M1 PF01433.15 KFM00634.1 - 1e-24 87.4 0.0 4e-13 49.2 0.0 2.8 3 0 0 3 3 3 2 Peptidase family M1 Peptidase_MA_2 PF13485.1 KFM00634.1 - 8.9e-11 41.9 1.7 1.7e-10 41.0 0.4 2.0 2 1 0 2 2 2 1 Peptidase MA superfamily DLH PF01738.13 KFM00634.1 - 0.04 13.1 0.0 0.069 12.4 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family FBPase PF00316.15 KFM00635.1 - 1.6e-122 408.3 0.0 1.9e-122 408.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 KFM00635.1 - 1.4e-05 24.5 0.2 2.8e-05 23.5 0.0 1.5 2 0 0 2 2 2 1 Inositol monophosphatase family DUF159 PF02586.9 KFM00635.1 - 0.16 11.4 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised ACR, COG2135 FBPase PF00316.15 KFM00636.1 - 7.2e-130 432.5 0.0 8.4e-130 432.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 KFM00636.1 - 7.6e-05 22.1 0.0 0.00018 20.9 0.0 1.6 2 0 0 2 2 2 1 Inositol monophosphatase family DUF159 PF02586.9 KFM00636.1 - 0.031 13.7 0.0 0.062 12.8 0.0 1.5 2 0 0 2 2 2 0 Uncharacterised ACR, COG2135 Peptidase_C1 PF00112.18 KFM00637.1 - 1.2e-89 299.9 2.3 1.8e-89 299.3 1.6 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 KFM00637.1 - 1.4e-13 50.8 1.9 2.5e-13 50.0 1.3 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 KFM00637.1 - 7.1e-06 24.8 3.1 0.00033 19.3 0.8 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Death PF00531.17 KFM00638.1 - 1.8e-17 62.8 0.1 1.4e-15 56.7 0.0 3.2 3 0 0 3 3 3 1 Death domain Pkinase PF00069.20 KFM00639.1 - 6.1e-68 228.7 0.0 1.1e-67 227.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ank PF00023.25 KFM00639.1 - 4.6e-66 215.5 7.1 3.5e-09 36.0 0.0 9.1 9 0 0 9 9 9 8 Ankyrin repeat Ank_2 PF12796.2 KFM00639.1 - 3.6e-65 216.3 10.1 6.7e-21 74.4 0.0 5.2 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFM00639.1 - 6.2e-51 169.9 5.7 2.5e-11 43.7 0.0 7.5 2 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM00639.1 - 4.1e-48 160.3 10.7 7.2e-10 38.7 0.0 7.2 1 1 6 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM00639.1 - 2e-46 151.3 7.8 2.9e-06 26.9 0.0 8.8 8 0 0 8 8 8 8 Ankyrin repeat Pkinase_Tyr PF07714.12 KFM00639.1 - 6.6e-34 117.1 0.0 1.2e-33 116.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFM00639.1 - 7.7e-06 25.1 0.0 2e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFM00639.1 - 9.2e-05 21.8 0.0 0.0002 20.7 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 KFM00639.1 - 0.016 14.8 0.0 0.038 13.5 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Glycos_trans_3N PF02885.12 KFM00639.1 - 0.04 13.5 0.0 0.13 11.8 0.0 1.9 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain ABC_tran PF00005.22 KFM00639.1 - 0.055 13.7 0.0 0.2 11.9 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 KFM00639.1 - 0.069 13.4 0.1 0.25 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain APH PF01636.18 KFM00639.1 - 0.079 12.6 0.1 0.2 11.3 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family AAA_29 PF13555.1 KFM00639.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DOR PF14839.1 KFM00641.1 - 3.5 7.3 8.3 4.4 7.0 5.8 1.2 1 0 0 1 1 1 0 DOR family Pro-rich PF15240.1 KFM00641.1 - 4.2 7.4 10.6 4.6 7.2 7.3 1.1 1 0 0 1 1 1 0 Proline-rich Fe-S_biosyn PF01521.15 KFM00642.1 - 1e-18 67.3 0.0 1.1e-18 67.1 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis IncA PF04156.9 KFM00643.1 - 0.0048 16.5 14.2 0.0048 16.5 9.9 2.7 1 1 1 2 2 2 1 IncA protein Peptidase_M14 PF00246.19 KFM00644.1 - 2.7e-26 92.8 0.0 7.6e-26 91.3 0.0 1.7 1 1 1 2 2 2 1 Zinc carboxypeptidase V-ATPase_H_N PF03224.9 KFM00644.1 - 9.3e-05 21.6 1.0 0.002 17.3 0.0 2.6 2 1 0 2 2 2 1 V-ATPase subunit H AstE_AspA PF04952.9 KFM00644.1 - 0.02 13.8 0.0 0.032 13.1 0.0 1.3 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Pkinase_Tyr PF07714.12 KFM00646.1 - 7e-98 326.8 0.0 9.4e-98 326.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM00646.1 - 4.1e-50 170.3 0.0 5.9e-50 169.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain I-set PF07679.11 KFM00646.1 - 7.5e-23 80.2 0.1 1.3e-12 47.4 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM00646.1 - 1.2e-09 38.1 2.1 1.8e-05 24.7 0.2 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 KFM00646.1 - 7.9e-09 35.9 8.6 5.7e-08 33.1 2.5 2.8 2 0 0 2 2 2 1 Immunoglobulin domain LRR_8 PF13855.1 KFM00646.1 - 3.8e-07 29.7 0.8 1e-06 28.3 0.5 1.8 1 0 0 1 1 1 1 Leucine rich repeat ig PF00047.20 KFM00646.1 - 5.9e-07 29.5 5.8 3.7e-05 23.7 0.3 2.9 3 0 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.7 KFM00646.1 - 0.0019 18.0 0.7 0.78 9.6 0.1 2.8 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain V-set PF07686.12 KFM00646.1 - 0.0039 17.0 0.3 0.082 12.8 0.1 2.8 1 1 1 2 2 2 1 Immunoglobulin V-set domain Kinase-like PF14531.1 KFM00646.1 - 0.0072 15.3 0.1 0.022 13.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like LRR_1 PF00560.28 KFM00646.1 - 0.016 15.1 2.4 0.041 13.9 0.4 2.8 2 0 0 2 2 1 0 Leucine Rich Repeat Herpes_gE PF02480.11 KFM00646.1 - 0.047 11.9 0.0 3.6 5.7 0.0 2.8 2 1 1 3 3 3 0 Alphaherpesvirus glycoprotein E LRR_4 PF12799.2 KFM00646.1 - 0.81 9.3 5.8 0.25 11.0 1.0 2.5 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Glycos_transf_4 PF00953.16 KFM00648.1 - 8.3e-35 119.9 16.9 8.3e-35 119.9 11.7 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 4 Gal_mutarotas_2 PF13802.1 KFM00648.1 - 0.0093 15.8 0.8 0.018 14.8 0.6 1.4 1 0 0 1 1 1 1 Galactose mutarotase-like DUF4133 PF13571.1 KFM00648.1 - 0.78 10.0 4.8 0.36 11.0 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4133) Porphobil_deam PF01379.15 KFM00649.1 - 5.2e-86 286.9 0.0 6.9e-86 286.5 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 KFM00649.1 - 1e-19 70.3 0.1 4e-18 65.2 0.1 2.6 1 1 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain CUE PF02845.11 KFM00649.1 - 0.023 14.1 0.0 2.8 7.5 0.0 2.6 2 0 0 2 2 2 0 CUE domain MGS PF02142.17 KFM00649.1 - 0.12 12.2 0.0 0.39 10.6 0.0 1.9 2 0 0 2 2 2 0 MGS-like domain VPS11_C PF12451.3 KFM00650.1 - 8.6e-20 70.3 2.4 8.7e-20 70.3 0.1 2.3 2 0 0 2 2 1 1 Vacuolar protein sorting protein 11 C terminal Clathrin PF00637.15 KFM00650.1 - 1.3e-17 63.7 12.8 5.5e-15 55.2 2.5 2.7 2 0 0 2 2 2 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 KFM00650.1 - 1.5e-07 31.1 8.7 4.7e-07 29.5 6.1 2.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFM00650.1 - 6e-07 29.3 7.2 1.4e-06 28.2 5.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFM00650.1 - 6.3e-06 26.2 3.3 1.7e-05 24.8 2.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KFM00650.1 - 5.9e-05 22.6 7.8 0.00013 21.4 5.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM00650.1 - 0.00059 19.4 5.7 0.0012 18.4 4.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM00650.1 - 0.0017 18.0 8.3 0.0043 16.7 5.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain TPR_11 PF13414.1 KFM00650.1 - 0.011 15.3 2.0 0.051 13.2 0.0 3.0 3 0 0 3 3 3 0 TPR repeat zf-C3HC4_4 PF15227.1 KFM00650.1 - 0.024 14.5 7.8 0.067 13.0 5.4 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 KFM00650.1 - 0.034 13.9 2.2 0.12 12.2 1.6 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 KFM00650.1 - 0.12 12.1 1.2 0.3 10.8 0.9 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DivIC PF04977.10 KFM00650.1 - 0.23 10.9 4.2 0.71 9.4 2.9 1.8 1 0 0 1 1 1 0 Septum formation initiator zf-Nse PF11789.3 KFM00650.1 - 0.37 10.3 5.1 1.1 8.8 3.5 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prefoldin_2 PF01920.15 KFM00650.1 - 0.83 9.4 12.1 6.3 6.6 3.4 3.8 3 0 0 3 3 3 0 Prefoldin subunit zf-RING-like PF08746.6 KFM00650.1 - 2.6 8.1 6.4 7.7 6.6 4.4 1.9 1 0 0 1 1 1 0 RING-like domain DEAD PF00270.24 KFM00651.1 - 4.7e-39 133.5 0.4 4.7e-39 133.5 0.3 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFM00651.1 - 3.6e-25 87.6 0.1 8.3e-25 86.4 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 KFM00651.1 - 0.00062 18.9 0.1 0.0011 18.0 0.1 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit SNF2_N PF00176.18 KFM00651.1 - 0.014 14.2 0.1 0.016 13.9 0.1 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain Fork_head PF00250.13 KFM00653.1 - 3.8e-23 81.3 0.0 4.5e-23 81.0 0.0 1.0 1 0 0 1 1 1 1 Fork head domain DUF3872 PF12988.2 KFM00653.1 - 0.0059 16.1 0.0 0.0063 16.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function, B. Theta Gene description (DUF3872) HTH_34 PF13601.1 KFM00653.1 - 0.028 14.4 0.0 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain CCDC84 PF14968.1 KFM00654.1 - 1.1e-44 153.3 7.0 1.2e-44 153.1 4.8 1.0 1 0 0 1 1 1 1 Coiled coil protein 84 Ribosomal_S25 PF03297.10 KFM00655.1 - 8.2e-41 138.3 0.4 9.2e-41 138.1 0.3 1.0 1 0 0 1 1 1 1 S25 ribosomal protein TrmB PF01978.14 KFM00655.1 - 0.0078 15.8 0.3 0.018 14.6 0.1 1.7 1 1 1 2 2 2 1 Sugar-specific transcriptional regulator TrmB Fe_dep_repress PF01325.14 KFM00655.1 - 0.023 14.6 0.1 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_24 PF13412.1 KFM00655.1 - 0.033 13.5 0.8 0.067 12.5 0.2 1.7 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 KFM00655.1 - 0.079 12.6 0.1 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 MarR family DUF387 PF04079.11 KFM00655.1 - 0.1 11.9 0.1 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative transcriptional regulators (Ypuh-like) Sybindin PF04099.7 KFM00656.1 - 7.6e-46 155.3 0.0 1.4e-45 154.4 0.0 1.4 1 1 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 KFM00656.1 - 1e-08 35.1 0.0 1.5e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region MFS_1 PF07690.11 KFM00657.1 - 1.6e-41 142.2 32.7 4.8e-40 137.3 16.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KFM00657.1 - 0.39 10.7 12.5 0.43 10.6 0.3 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1228) Adap_comp_sub PF00928.16 KFM00658.1 - 8.6e-39 133.2 0.3 1.3e-38 132.5 0.2 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KFM00658.1 - 4.7e-06 26.3 0.3 8.6e-06 25.5 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain IFT46_B_C PF12317.3 KFM00659.1 - 6e-99 329.7 0.8 7e-99 329.5 0.6 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal TPR_11 PF13414.1 KFM00661.1 - 2.7e-14 52.5 1.3 5e-12 45.2 0.1 2.4 2 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KFM00661.1 - 1.3e-12 46.6 0.4 0.00052 19.7 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KFM00661.1 - 1.6e-08 33.8 0.0 0.00051 19.5 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFM00661.1 - 2e-07 31.5 2.6 2e-07 31.5 1.8 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFM00661.1 - 4.4e-05 23.3 3.1 0.0026 17.6 1.4 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFM00661.1 - 0.00059 19.8 0.1 0.0023 17.9 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFM00661.1 - 0.0014 18.4 1.3 0.0014 18.4 0.9 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFM00661.1 - 0.0071 16.6 0.5 0.018 15.3 0.3 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFM00661.1 - 0.014 15.7 1.8 28 5.4 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFM00661.1 - 0.043 14.4 12.0 0.81 10.4 1.2 3.4 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 KFM00661.1 - 5.8 7.6 8.6 1.2 9.8 1.2 3.3 3 1 0 3 3 2 0 Tetratricopeptide repeat FYRC PF05965.9 KFM00662.1 - 1.3e-23 82.6 0.0 3.5e-23 81.1 0.0 1.9 1 0 0 1 1 1 1 F/Y rich C-terminus SET PF00856.23 KFM00662.1 - 1.9e-23 83.5 0.7 1.9e-23 83.5 0.5 4.6 5 0 0 5 5 5 1 SET domain FYRN PF05964.9 KFM00662.1 - 2.4e-16 58.9 0.2 4.9e-16 57.9 0.1 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus zf-HC5HC2H PF13771.1 KFM00662.1 - 1e-14 54.4 11.0 1e-14 54.4 7.6 5.6 4 1 1 5 5 5 1 PHD-like zinc-binding domain PHD PF00628.24 KFM00662.1 - 3.2e-14 52.3 53.6 3.3e-08 33.0 8.4 5.7 5 1 2 7 7 7 3 PHD-finger zf-CXXC PF02008.15 KFM00662.1 - 2.1e-13 49.8 24.3 2.1e-13 49.8 16.9 5.4 5 0 0 5 5 5 1 CXXC zinc finger domain zf-HC5HC2H_2 PF13832.1 KFM00662.1 - 1.7e-08 34.3 9.9 1.7e-08 34.3 6.9 5.2 4 1 1 5 5 5 1 PHD-zinc-finger like domain PHD_2 PF13831.1 KFM00662.1 - 1.2e-05 24.4 25.8 0.0014 17.8 2.0 4.2 3 0 0 3 3 3 2 PHD-finger Ufd2P_core PF10408.4 KFM00664.1 - 4.6e-185 616.4 12.6 4.6e-185 616.4 8.7 1.4 2 0 0 2 2 2 1 Ubiquitin elongating factor core U-box PF04564.10 KFM00664.1 - 1.9e-32 111.0 1.0 5.3e-32 109.6 0.4 2.1 2 0 0 2 2 2 1 U-box domain IRK PF01007.15 KFM00665.1 - 6.6e-123 409.8 2.9 7.4e-123 409.6 2.0 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 KFM00665.1 - 0.00015 21.3 0.9 0.00031 20.3 0.6 1.6 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.26 KFM00665.1 - 0.0022 17.2 4.9 0.0034 16.6 3.4 1.2 1 0 0 1 1 1 1 Ion transport protein PMP22_Claudin PF00822.15 KFM00666.1 - 7.7e-12 45.1 0.0 8.7e-12 45.0 0.0 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFM00666.1 - 0.00037 20.2 0.1 0.00046 19.9 0.1 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction UCH PF00443.24 KFM00667.1 - 6.8e-50 169.6 0.6 1.3e-49 168.7 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFM00667.1 - 4e-17 62.6 4.5 6.2e-14 52.1 0.1 3.0 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Neur_chan_LBD PF02931.18 KFM00668.1 - 2.7e-52 177.0 1.8 3.6e-52 176.6 1.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFM00668.1 - 3.3e-31 108.9 0.0 4.8e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region RRM_1 PF00076.17 KFM00669.1 - 4.1e-09 35.9 0.0 6e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM00669.1 - 8.7e-07 28.8 0.0 1.3e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM00669.1 - 1.3e-05 24.9 0.0 2.2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 KFM00670.1 - 3.6e-17 63.1 0.0 4.6e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Exonuclease I-set PF07679.11 KFM00672.1 - 8e-25 86.5 0.1 6.5e-11 41.9 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM00672.1 - 9.5e-25 86.5 0.5 1.3e-10 41.2 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 KFM00672.1 - 2.8e-19 69.1 2.2 2e-07 30.8 0.1 4.3 3 1 0 3 3 3 3 Immunoglobulin V-set domain Ig_3 PF13927.1 KFM00672.1 - 6.2e-17 61.8 8.5 2.2e-08 34.4 0.0 3.9 4 0 0 4 4 3 3 Immunoglobulin domain ig PF00047.20 KFM00672.1 - 1.9e-16 59.9 2.9 6.3e-05 23.0 0.0 4.0 4 0 0 4 4 4 3 Immunoglobulin domain C2-set_2 PF08205.7 KFM00672.1 - 2.2e-12 46.6 2.0 1e-10 41.3 0.0 3.3 4 0 0 4 4 3 1 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.11 KFM00672.1 - 0.00041 18.7 0.3 0.3 9.3 0.0 3.0 2 1 1 3 3 3 2 Alphaherpesvirus glycoprotein E C2-set PF05790.10 KFM00672.1 - 0.0046 16.8 0.0 27 4.7 0.0 4.1 4 0 0 4 4 4 0 Immunoglobulin C2-set domain OppC_N PF12911.2 KFM00672.1 - 0.033 13.5 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Rubella_E2 PF05749.6 KFM00672.1 - 0.048 12.9 0.2 0.087 12.0 0.2 1.5 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 Syndecan PF01034.15 KFM00672.1 - 0.049 13.3 0.1 0.29 10.7 0.1 2.0 2 0 0 2 2 2 0 Syndecan domain DUF3439 PF11921.3 KFM00672.1 - 0.13 12.0 7.8 0.27 10.9 5.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) zf-ZPR1 PF03367.8 KFM00673.1 - 1.8e-113 375.0 0.2 8.2e-58 194.1 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain DUF1069 PF06370.6 KFM00673.1 - 0.057 12.7 0.0 0.082 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1069) zinc-ribbons_6 PF07191.7 KFM00673.1 - 0.1 12.3 1.4 0.13 12.0 0.2 1.7 2 0 0 2 2 2 0 zinc-ribbons Elf1 PF05129.8 KFM00673.1 - 0.16 11.6 1.4 1.3 8.7 0.2 2.3 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like UPF0547 PF10571.4 KFM00673.1 - 1.9 8.2 5.3 13 5.6 0.0 3.0 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Apolipoprotein PF01442.13 KFM00674.1 - 1.2e-23 83.7 0.2 1.8e-23 83.1 0.2 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF2743 PF10899.3 KFM00674.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2743) CorA PF01544.13 KFM00674.1 - 0.18 10.8 0.5 0.22 10.4 0.3 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Apolipoprotein PF01442.13 KFM00675.1 - 2.4e-56 190.4 20.4 2.7e-56 190.2 14.2 1.0 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.7 KFM00675.1 - 2.7e-07 30.4 0.8 0.024 14.4 0.1 3.1 1 1 2 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF883 PF05957.8 KFM00675.1 - 3.9e-07 30.3 11.6 0.067 13.5 0.9 4.1 1 1 3 4 4 4 2 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 KFM00675.1 - 4.9e-07 30.0 10.7 7.6 6.9 7.4 4.3 1 1 0 1 1 1 0 YtxH-like protein DUF445 PF04286.7 KFM00675.1 - 4.5e-05 23.1 4.9 5.7e-05 22.8 3.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF445) Bacillus_HBL PF05791.6 KFM00675.1 - 0.00022 20.6 2.9 0.23 10.8 0.2 3.0 1 1 2 3 3 3 1 Bacillus haemolytic enterotoxin (HBL) DUF1664 PF07889.7 KFM00675.1 - 0.00033 20.4 4.4 0.2 11.4 0.1 2.6 1 1 2 3 3 3 2 Protein of unknown function (DUF1664) Dynamin_M PF01031.15 KFM00675.1 - 0.00047 19.0 2.4 0.00081 18.2 1.5 1.5 1 1 0 1 1 1 1 Dynamin central region Exonuc_VII_L PF02601.10 KFM00675.1 - 0.0015 17.7 7.2 0.0036 16.5 5.0 1.5 1 1 0 1 1 1 1 Exonuclease VII, large subunit 4HB_MCP_1 PF12729.2 KFM00675.1 - 0.0017 17.7 8.1 0.052 12.9 4.6 3.0 1 1 1 2 2 2 1 Four helix bundle sensory module for signal transduction DUF948 PF06103.6 KFM00675.1 - 0.0031 17.3 3.0 0.13 12.1 0.1 3.4 1 1 3 4 4 4 1 Bacterial protein of unknown function (DUF948) DUF2959 PF11172.3 KFM00675.1 - 0.0031 17.3 10.3 0.028 14.1 3.4 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF2959) AAA_13 PF13166.1 KFM00675.1 - 0.0038 15.7 6.4 0.0052 15.3 4.4 1.2 1 0 0 1 1 1 1 AAA domain DUF2580 PF10824.3 KFM00675.1 - 0.004 17.4 0.0 5.9 7.3 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2580) Prominin PF05478.6 KFM00675.1 - 0.0047 14.5 3.6 0.04 11.4 0.2 1.9 1 1 1 2 2 2 2 Prominin KMP11 PF03037.11 KFM00675.1 - 0.0078 16.7 4.0 0.94 10.1 0.7 3.2 1 1 2 3 3 3 1 Kinetoplastid membrane protein 11 Laminin_II PF06009.7 KFM00675.1 - 0.0094 15.7 8.3 0.043 13.5 1.8 2.5 1 1 2 3 3 3 2 Laminin Domain II Peptidase_M75 PF09375.5 KFM00675.1 - 0.017 14.4 3.8 0.97 8.6 2.2 2.7 1 1 2 3 3 3 0 Imelysin DUF4015 PF13200.1 KFM00675.1 - 0.022 13.6 1.2 0.15 10.9 0.1 2.1 2 0 0 2 2 2 0 Putative glycosyl hydrolase domain Hemerythrin PF01814.18 KFM00675.1 - 0.024 14.7 7.6 0.3 11.2 1.5 2.6 1 1 2 3 3 3 0 Hemerythrin HHE cation binding domain ERM PF00769.14 KFM00675.1 - 0.028 13.9 12.4 0.038 13.5 8.6 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Apo-CIII PF05778.7 KFM00675.1 - 0.032 13.6 0.0 0.62 9.4 0.0 2.7 3 0 0 3 3 2 0 Apolipoprotein CIII (Apo-CIII) ING PF12998.2 KFM00675.1 - 0.035 14.3 11.4 0.048 13.9 3.7 2.3 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF72 PF01904.13 KFM00675.1 - 0.035 13.8 5.9 0.56 9.9 1.6 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF72 ApoLp-III PF07464.6 KFM00675.1 - 0.037 14.0 10.8 0.65 10.0 6.8 2.5 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF1054 PF06335.7 KFM00675.1 - 0.038 13.6 1.7 3 7.4 0.0 3.4 1 1 2 4 4 3 0 Protein of unknown function (DUF1054) WXG100 PF06013.7 KFM00675.1 - 0.04 13.9 2.5 1 9.4 0.1 3.8 1 1 3 4 4 4 0 Proteins of 100 residues with WXG NIT PF08376.5 KFM00675.1 - 0.043 13.3 4.0 0.95 8.9 0.2 2.2 2 0 0 2 2 2 0 Nitrate and nitrite sensing COG2 PF06148.6 KFM00675.1 - 0.045 13.6 10.0 5.9 6.7 1.9 4.0 1 1 3 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Apc4 PF12896.2 KFM00675.1 - 0.046 13.0 2.9 3.1 7.0 0.1 3.1 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 4 ApoO PF09769.4 KFM00675.1 - 0.047 13.4 3.6 0.63 9.7 1.4 2.7 1 1 1 2 2 2 0 Apolipoprotein O Nup54 PF13874.1 KFM00675.1 - 0.05 13.2 8.5 0.16 11.5 4.3 2.3 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 OmpH PF03938.9 KFM00675.1 - 0.051 13.5 14.0 2.5 8.0 9.7 2.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Syntaxin_2 PF14523.1 KFM00675.1 - 0.057 13.4 8.1 59 3.7 5.6 3.3 1 1 0 1 1 1 0 Syntaxin-like protein Phe_tRNA-synt_N PF02912.13 KFM00675.1 - 0.059 13.1 7.5 0.21 11.3 0.2 3.6 2 2 3 5 5 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain Effector_1 PF04518.7 KFM00675.1 - 0.065 12.2 4.3 0.033 13.1 0.6 1.9 1 1 1 2 2 2 0 Effector from type III secretion system TBPIP PF07106.8 KFM00675.1 - 0.068 12.7 13.5 0.093 12.2 4.8 2.6 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2317 PF10079.4 KFM00675.1 - 0.069 11.7 13.4 0.31 9.5 6.3 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2317) Matrilin_ccoil PF10393.4 KFM00675.1 - 0.082 12.2 15.6 4 6.8 0.3 4.7 4 2 0 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin ApoC-I PF04691.7 KFM00675.1 - 0.084 12.5 7.3 0.43 10.2 0.3 4.0 2 2 4 6 6 5 0 Apolipoprotein C-I (ApoC-1) Fib_alpha PF08702.5 KFM00675.1 - 0.084 12.9 5.2 0.45 10.6 1.9 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family PGK PF00162.14 KFM00675.1 - 0.087 11.3 2.6 0.36 9.3 0.5 2.0 1 1 1 2 2 2 0 Phosphoglycerate kinase AAR2 PF05282.6 KFM00675.1 - 0.1 11.5 4.5 0.2 10.5 0.9 2.2 1 1 2 3 3 3 0 AAR2 protein PA28_alpha PF02251.13 KFM00675.1 - 0.12 12.5 5.6 18 5.6 0.0 4.7 1 1 2 4 4 4 0 Proteasome activator pa28 alpha subunit DUF1451 PF07295.6 KFM00675.1 - 0.13 11.9 10.5 0.18 11.5 2.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1451) NPV_P10 PF05531.7 KFM00675.1 - 0.13 12.4 4.8 1.7 8.9 0.8 3.8 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein CpXC PF14353.1 KFM00675.1 - 0.14 12.1 5.4 7.3 6.5 1.4 3.2 1 1 1 2 2 2 0 CpXC protein Lsr2 PF11774.3 KFM00675.1 - 0.15 12.0 2.1 3.8 7.4 0.1 2.5 1 1 0 2 2 2 0 Lsr2 DUF4404 PF14357.1 KFM00675.1 - 0.18 12.2 10.9 0.73 10.2 0.5 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4404) DUF668 PF05003.7 KFM00675.1 - 0.18 12.0 5.2 0.99 9.6 0.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF668) Ded_cyto PF06920.8 KFM00675.1 - 0.19 11.0 6.0 2.9 7.1 0.9 2.4 2 0 0 2 2 2 0 Dedicator of cytokinesis DUF3829 PF12889.2 KFM00675.1 - 0.19 10.8 7.5 0.31 10.1 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) Acyl-CoA_dh_C PF12806.2 KFM00675.1 - 0.2 11.5 3.3 0.76 9.6 0.1 3.0 1 1 2 3 3 3 0 Acetyl-CoA dehydrogenase C-terminal like Adenylsucc_synt PF00709.16 KFM00675.1 - 0.21 10.2 5.4 2.8 6.4 0.8 2.1 1 1 1 2 2 2 0 Adenylosuccinate synthetase Spc42p PF11544.3 KFM00675.1 - 0.21 11.5 7.5 0.071 13.0 1.1 2.7 2 1 1 3 3 2 0 Spindle pole body component Spc42p Bul1_C PF04426.7 KFM00675.1 - 0.21 10.7 2.6 0.95 8.5 0.6 2.1 1 1 1 2 2 2 0 Bul1 C terminus Snapin_Pallidin PF14712.1 KFM00675.1 - 0.22 11.8 11.3 2.4 8.5 1.7 2.9 1 1 2 3 3 2 0 Snapin/Pallidin Cupin_4 PF08007.7 KFM00675.1 - 0.22 10.7 3.3 0.3 10.2 2.1 1.4 1 1 0 1 1 1 0 Cupin superfamily protein Phage_min_cap2 PF06152.6 KFM00675.1 - 0.23 10.3 3.7 0.53 9.2 2.3 1.6 1 1 1 2 2 2 0 Phage minor capsid protein 2 ApoA-II PF04711.8 KFM00675.1 - 0.24 11.3 5.5 5.8 6.8 0.2 3.7 1 1 2 3 3 3 0 Apolipoprotein A-II (ApoA-II) DUF2935 PF11155.3 KFM00675.1 - 0.26 11.3 4.3 2.2 8.3 3.0 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) VirE PF05272.6 KFM00675.1 - 0.28 10.6 4.3 0.72 9.2 0.4 2.2 1 1 1 2 2 2 0 Virulence-associated protein E His_Phos_1 PF00300.17 KFM00675.1 - 0.28 11.2 6.4 0.33 11.0 1.1 2.6 1 1 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) KapB PF08810.5 KFM00675.1 - 0.29 11.1 7.0 1.2 9.1 0.7 3.2 1 1 2 3 3 3 0 Kinase associated protein B YlqD PF11068.3 KFM00675.1 - 0.33 11.0 14.3 1.6 8.7 1.9 2.7 1 1 2 3 3 3 0 YlqD protein eIF3_N PF09440.5 KFM00675.1 - 0.33 11.1 8.1 2 8.5 0.2 2.5 1 1 2 3 3 3 0 eIF3 subunit 6 N terminal domain PhaP_Bmeg PF09602.5 KFM00675.1 - 0.35 10.6 9.0 3.3 7.5 3.3 2.6 1 1 2 3 3 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) RRF PF01765.14 KFM00675.1 - 0.38 10.2 9.5 1.6 8.2 0.4 2.5 1 1 1 2 2 2 0 Ribosome recycling factor DUF2937 PF11157.3 KFM00675.1 - 0.4 9.9 4.7 1.3 8.3 0.1 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF2937) DUF1732 PF08340.6 KFM00675.1 - 0.42 10.4 4.6 0.32 10.8 0.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1732) NDUF_B6 PF09782.4 KFM00675.1 - 0.47 10.2 5.4 1 9.1 3.3 2.1 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit DUF3538 PF12057.3 KFM00675.1 - 0.48 10.0 2.5 15 5.2 0.3 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3538) Gp-FAR-1 PF05823.7 KFM00675.1 - 0.53 10.2 8.0 3.2 7.7 5.3 2.2 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) TipAS PF07739.8 KFM00675.1 - 0.58 10.4 7.0 0.39 11.0 0.9 2.7 1 1 2 3 3 3 0 TipAS antibiotic-recognition domain IZUMO PF15005.1 KFM00675.1 - 0.59 10.1 7.5 1.5 8.8 2.7 2.7 1 1 2 3 3 3 0 Izumo sperm-egg fusion Vac_Fusion PF02346.11 KFM00675.1 - 0.77 9.2 4.9 2.7 7.4 0.7 3.2 3 1 0 3 3 2 0 Chordopoxvirus fusion protein Prefoldin PF02996.12 KFM00675.1 - 0.78 9.3 11.7 7.9 6.1 0.3 4.3 1 1 4 5 5 5 0 Prefoldin subunit RNase_E_G PF10150.4 KFM00675.1 - 0.88 8.7 5.4 1.2 8.3 1.1 1.9 1 1 1 2 2 2 0 Ribonuclease E/G family Syntaxin PF00804.20 KFM00675.1 - 0.95 9.6 9.2 0.54 10.4 2.3 2.5 1 1 1 2 2 2 0 Syntaxin HK97-gp10_like PF04883.7 KFM00675.1 - 0.97 10.4 8.0 3.6 8.5 0.6 3.5 3 1 0 3 3 2 0 Bacteriophage HK97-gp10, putative tail-component Atg14 PF10186.4 KFM00675.1 - 0.98 8.3 13.4 0.98 8.2 6.4 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 FUSC PF04632.7 KFM00675.1 - 1.2 7.5 7.6 4.7 5.5 1.8 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family HAD_2 PF13419.1 KFM00675.1 - 1.2 9.2 3.1 23 5.1 0.2 2.2 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase HrcA PF01628.16 KFM00675.1 - 1.5 8.3 5.6 13 5.2 0.5 2.5 1 1 1 2 2 2 0 HrcA protein C terminal domain Swi5 PF07061.6 KFM00675.1 - 1.6 8.5 6.0 6.1 6.6 0.0 3.4 1 1 1 2 2 1 0 Swi5 Peptidase_S46 PF10459.4 KFM00675.1 - 1.6 7.0 7.6 1.9 6.7 5.3 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF972 PF06156.8 KFM00675.1 - 1.7 9.0 13.2 34 4.8 5.5 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DNA_primase_lrg PF04104.9 KFM00675.1 - 1.8 7.7 7.6 10 5.2 2.2 2.6 1 1 1 2 2 2 0 Eukaryotic and archaeal DNA primase, large subunit FlgN PF05130.7 KFM00675.1 - 1.9 8.7 16.7 5.2 7.3 4.8 3.1 1 1 1 2 2 2 0 FlgN protein CDC37_N PF03234.9 KFM00675.1 - 1.9 8.7 9.1 5 7.4 5.7 1.9 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding HalX PF08663.5 KFM00675.1 - 2 8.4 9.5 12 5.9 1.4 4.7 1 1 3 4 4 4 0 HalX domain SBP_bac_7 PF03480.8 KFM00675.1 - 2 7.4 11.1 1.6 7.7 0.5 2.7 1 1 2 3 3 3 0 Bacterial extracellular solute-binding protein, family 7 DUF3106 PF11304.3 KFM00675.1 - 2.2 8.7 10.6 0.87 10.0 4.4 2.4 1 1 2 3 3 1 0 Protein of unknown function (DUF3106) NYD-SP28 PF14772.1 KFM00675.1 - 2.6 8.1 12.4 0.89 9.6 4.0 2.4 1 1 1 2 2 2 0 Sperm tail Toxin_39 PF15500.1 KFM00675.1 - 2.9 8.0 4.7 2.7 8.1 0.3 2.6 1 1 1 3 3 2 0 Putative RNase-like toxin Flg_hook PF02120.11 KFM00675.1 - 3 7.5 7.1 1.3 8.7 0.6 3.4 2 1 1 4 4 2 0 Flagellar hook-length control protein FliK IncA PF04156.9 KFM00675.1 - 3.1 7.3 18.8 23 4.4 13.0 2.2 1 1 0 1 1 1 0 IncA protein TMPIT PF07851.8 KFM00675.1 - 3.3 6.6 6.6 3.5 6.6 2.7 1.9 1 1 1 2 2 2 0 TMPIT-like protein LUC7 PF03194.10 KFM00675.1 - 3.5 7.0 10.2 19 4.6 7.1 1.9 1 1 0 1 1 1 0 LUC7 N_terminus Erp_C PF06780.6 KFM00675.1 - 3.5 7.4 11.5 4.2 7.1 1.0 2.9 1 1 3 4 4 4 0 Erp protein C-terminus FlaC_arch PF05377.6 KFM00675.1 - 3.7 7.5 10.1 17 5.3 0.2 4.2 2 2 2 4 4 3 0 Flagella accessory protein C (FlaC) DUF2203 PF09969.4 KFM00675.1 - 4 7.6 7.1 66 3.7 4.9 2.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) MutS_IV PF05190.13 KFM00675.1 - 5.9 7.1 14.5 50 4.1 0.1 4.8 2 1 2 5 5 5 0 MutS family domain IV DUF342 PF03961.8 KFM00675.1 - 6.4 5.0 11.4 1.7 6.9 2.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) V-SNARE PF05008.10 KFM00675.1 - 8.5 6.6 11.1 8.4 6.6 1.1 3.6 2 2 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus ParcG PF10274.4 KFM00676.1 - 3.6 7.4 5.5 0.85 9.4 0.4 2.1 1 1 2 3 3 3 0 Parkin co-regulated protein Pkinase PF00069.20 KFM00677.1 - 1.5e-68 230.8 0.1 3.2e-68 229.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM00677.1 - 2.6e-35 121.7 1.8 5.4e-35 120.7 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM00677.1 - 5.6e-07 28.8 0.0 1.7e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFM00677.1 - 0.01 14.8 0.3 0.025 13.6 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Lipase_GDSL_2 PF13472.1 KFM00678.1 - 2.1e-17 63.8 0.0 3e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KFM00678.1 - 7.8e-07 29.1 0.0 1.1e-06 28.6 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 KFM00678.1 - 0.0019 17.9 0.0 0.0025 17.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family SID-1_RNA_chan PF13965.1 KFM00679.1 - 1.3e-08 33.5 0.3 1.3e-08 33.5 0.2 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 SCIMP PF15050.1 KFM00679.1 - 0.081 12.8 0.4 0.095 12.5 0.3 1.1 1 0 0 1 1 1 0 SCIMP protein DUF2781 PF10914.3 KFM00679.1 - 0.091 12.5 0.3 0.091 12.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) Peptidase_S8 PF00082.17 KFM00680.1 - 5.8e-60 202.8 1.9 7.6e-60 202.4 1.3 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 KFM00680.1 - 4.6e-26 90.4 0.0 9.8e-26 89.3 0.0 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain zf-RING_2 PF13639.1 KFM00681.1 - 6.9e-07 28.9 7.4 1.3e-06 28.0 5.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KFM00681.1 - 0.00055 19.9 8.6 0.0012 18.9 5.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KFM00681.1 - 0.019 14.6 10.4 0.037 13.6 7.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 KFM00681.1 - 0.025 14.5 4.9 0.047 13.6 3.4 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_5 PF14634.1 KFM00681.1 - 0.041 13.6 8.7 0.083 12.6 6.0 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFM00681.1 - 0.066 13.2 9.0 0.15 12.1 6.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 KFM00681.1 - 0.072 13.1 9.0 0.14 12.2 6.3 1.5 1 0 0 1 1 1 0 RING-variant domain zf-Apc11 PF12861.2 KFM00681.1 - 0.15 11.9 7.1 0.3 10.9 4.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Asp PF00026.18 KFM00682.1 - 2e-35 122.5 0.0 3.1e-35 121.9 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 KFM00682.1 - 3.3e-11 42.9 0.0 4.9e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal WW PF00397.21 KFM00683.1 - 4.6e-09 35.9 0.3 6.7e-09 35.4 0.2 1.2 1 0 0 1 1 1 1 WW domain Homeobox PF00046.24 KFM00683.1 - 0.02 14.5 0.1 0.055 13.0 0.0 1.7 2 0 0 2 2 2 0 Homeobox domain Reo_sigmaC PF04582.7 KFM00684.1 - 8 5.5 20.3 0.19 10.8 2.2 3.3 3 0 0 3 3 3 0 Reovirus sigma C capsid protein IQ PF00612.22 KFM00685.1 - 0.00011 21.5 1.4 0.00024 20.4 1.0 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif Zona_pellucida PF00100.18 KFM00686.1 - 4e-44 151.0 0.2 7.4e-44 150.1 0.1 1.4 1 0 0 1 1 1 1 Zona pellucida-like domain Pkinase PF00069.20 KFM00687.1 - 4.8e-46 157.0 0.2 3.2e-25 88.7 0.1 3.0 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFM00687.1 - 2.5e-17 62.7 0.0 2e-13 50.0 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 KFM00687.1 - 0.012 15.3 0.0 0.063 13.0 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KFM00687.1 - 0.027 13.4 0.4 8 5.3 0.0 2.8 3 0 0 3 3 3 0 Kinase-like Sec63 PF02889.11 KFM00688.1 - 1.5e-46 159.0 1.8 2.3e-46 158.4 1.2 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 KFM00688.1 - 1.6e-27 96.0 0.0 1.4e-26 92.9 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFM00688.1 - 2.3e-11 43.3 0.0 7.7e-11 41.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFM00688.1 - 5.5e-10 39.3 0.0 1.3e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KFM00688.1 - 0.0043 17.2 0.0 0.051 13.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 KFM00688.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain zf-C2H2_4 PF13894.1 KFM00689.1 - 2.4e-11 43.0 49.8 0.0042 17.3 0.2 9.4 9 0 0 9 9 9 5 C2H2-type zinc finger zf-C2H2 PF00096.21 KFM00689.1 - 0.00036 20.6 57.0 0.00044 20.4 0.3 9.0 8 1 0 8 8 8 4 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KFM00689.1 - 0.0016 18.4 18.0 0.29 11.3 0.0 5.7 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 KFM00689.1 - 0.0054 16.8 2.1 0.0054 16.8 1.5 8.1 11 0 0 11 11 11 3 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 KFM00689.1 - 0.047 13.6 0.1 0.047 13.6 0.1 5.6 6 0 0 6 6 6 0 C2H2-type zinc finger zf-C2H2_7 PF15269.1 KFM00689.1 - 0.16 11.8 24.2 0.16 11.8 2.0 5.3 4 1 1 5 5 5 0 Zinc-finger zf-H2C2_2 PF13465.1 KFM00689.1 - 0.36 11.2 46.9 1 9.7 3.1 9.8 8 1 1 9 9 9 0 Zinc-finger double domain Glutaredoxin PF00462.19 KFM00689.1 - 1.1 9.3 4.6 14 5.7 0.2 3.9 4 0 0 4 4 4 0 Glutaredoxin DUF3733 PF12534.3 KFM00690.1 - 3.3e-50 167.2 14.3 3.6e-28 96.6 0.7 3.1 3 0 0 3 3 3 2 Leucine-rich repeat containing protein 8 LRR_8 PF13855.1 KFM00690.1 - 2.4e-38 129.7 34.6 6.2e-14 51.4 2.5 6.5 5 1 2 7 7 7 5 Leucine rich repeat LRR_4 PF12799.2 KFM00690.1 - 1.5e-30 104.2 38.2 2.8e-09 36.4 0.5 8.6 8 1 1 9 9 9 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM00690.1 - 1.3e-14 51.9 30.7 0.018 14.9 0.1 11.6 10 1 0 10 10 10 6 Leucine Rich Repeat LRR_7 PF13504.1 KFM00690.1 - 3.7e-10 38.3 33.9 0.097 12.9 0.4 12.1 12 1 0 12 12 12 3 Leucine rich repeat LRR_6 PF13516.1 KFM00690.1 - 0.00079 19.2 30.6 0.4 10.8 0.0 9.5 10 0 0 10 10 10 1 Leucine Rich repeat LRR_9 PF14580.1 KFM00690.1 - 0.0017 17.9 9.6 0.037 13.5 0.4 3.2 1 1 2 3 3 3 2 Leucine-rich repeat DUF3733 PF12534.3 KFM00691.1 - 9.6e-55 181.7 8.6 4.9e-31 105.8 0.4 2.7 2 0 0 2 2 2 2 Leucine-rich repeat containing protein 8 LRR_8 PF13855.1 KFM00691.1 - 4.1e-35 119.3 44.3 2.8e-12 46.1 2.6 7.8 2 1 7 9 9 9 8 Leucine rich repeat LRR_4 PF12799.2 KFM00691.1 - 1e-30 104.8 37.7 2.6e-08 33.3 0.3 10.2 5 4 2 9 9 9 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM00691.1 - 3.9e-12 44.4 38.4 0.32 11.1 0.0 12.0 13 2 0 13 13 13 5 Leucine Rich Repeat LRR_5 PF13306.1 KFM00691.1 - 9e-09 35.1 9.3 0.00015 21.4 0.4 4.1 2 1 1 3 3 3 2 Leucine rich repeats (6 copies) LRR_7 PF13504.1 KFM00691.1 - 7.9e-06 25.2 31.4 12 6.6 0.0 12.4 14 0 0 14 14 14 1 Leucine rich repeat VHL PF01847.11 KFM00691.1 - 0.076 12.5 0.2 0.17 11.4 0.1 1.6 1 0 0 1 1 1 0 von Hippel-Lindau disease tumour suppressor protein DUF3733 PF12534.3 KFM00692.1 - 2.9e-43 144.9 12.1 4.2e-25 86.8 1.9 2.6 2 0 0 2 2 2 2 Leucine-rich repeat containing protein 8 LRR_8 PF13855.1 KFM00692.1 - 1.5e-34 117.5 55.0 4.5e-12 45.5 4.3 7.5 5 2 2 7 7 7 6 Leucine rich repeat LRR_4 PF12799.2 KFM00692.1 - 9.6e-28 95.3 66.5 3.7e-09 35.9 0.4 10.0 3 2 3 9 9 9 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFM00692.1 - 6.3e-08 32.3 9.6 0.00017 21.2 1.7 3.8 1 1 3 4 4 4 3 Leucine rich repeats (6 copies) LRR_1 PF00560.28 KFM00692.1 - 5.1e-07 28.8 53.2 0.0095 15.8 0.0 13.0 11 3 2 13 13 13 4 Leucine Rich Repeat LRR_7 PF13504.1 KFM00692.1 - 0.021 14.9 48.2 0.29 11.5 0.0 13.1 14 0 0 14 14 14 0 Leucine rich repeat LRR_9 PF14580.1 KFM00692.1 - 0.022 14.3 15.8 0.088 12.3 0.5 3.5 1 1 2 3 3 3 0 Leucine-rich repeat LRR_6 PF13516.1 KFM00692.1 - 0.24 11.5 0.0 0.24 11.5 0.0 10.2 11 2 2 13 13 13 0 Leucine Rich repeat Aminotran_1_2 PF00155.16 KFM00693.1 - 2.9e-52 177.8 0.0 3.3e-52 177.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KFM00693.1 - 4.1e-05 22.0 0.0 0.00019 19.8 0.0 1.8 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KFM00693.1 - 0.0018 17.3 0.0 0.0032 16.5 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF914 PF06027.7 KFM00693.1 - 0.046 12.5 0.0 0.068 11.9 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) TFIIB PF00382.14 KFM00694.1 - 4.2e-53 177.0 2.2 6.3e-26 89.9 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 KFM00694.1 - 1.7e-13 49.6 0.3 2.7e-13 48.9 0.2 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 KFM00694.1 - 1.1e-08 34.6 0.0 4.8e-06 26.1 0.0 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFM00694.1 - 0.00027 20.8 0.3 0.058 13.3 0.0 2.6 2 1 0 2 2 2 2 Cyclin, C-terminal domain Sigma70_r4 PF04545.11 KFM00694.1 - 0.0034 16.6 0.1 0.094 12.0 0.0 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 Pkinase PF00069.20 KFM00695.1 - 3.9e-61 206.4 0.0 7.6e-61 205.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM00695.1 - 8.4e-39 133.1 0.0 1.2e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 KFM00695.1 - 6.9e-33 112.2 14.1 1.6e-17 62.9 4.5 2.3 2 0 0 2 2 2 2 Hr1 repeat Uds1 PF15456.1 KFM00695.1 - 1.4e-06 28.3 6.8 0.00098 19.1 1.1 2.4 1 1 1 2 2 2 2 Up-regulated During Septation Kinase-like PF14531.1 KFM00695.1 - 4.9e-06 25.7 0.0 3.1e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like DUF3416 PF11896.3 KFM00695.1 - 0.017 15.0 3.2 0.74 9.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3416) RVT_1 PF00078.22 KFM00696.1 - 0.014 14.7 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) LIM PF00412.17 KFM00697.1 - 2.8e-17 62.5 1.3 3.6e-17 62.1 0.9 1.1 1 0 0 1 1 1 1 LIM domain zf-ribbon_3 PF13248.1 KFM00697.1 - 0.011 14.9 2.7 1.2 8.4 0.0 2.8 2 1 0 2 2 2 0 zinc-ribbon domain Prok-RING_1 PF14446.1 KFM00697.1 - 0.016 14.9 1.5 0.046 13.4 1.0 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Vps39_2 PF10367.4 KFM00697.1 - 0.024 14.7 2.0 0.092 12.9 0.3 2.1 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 DUF2175 PF09943.4 KFM00697.1 - 0.042 13.9 0.1 3.2 7.8 0.1 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) DUF164 PF02591.10 KFM00697.1 - 0.075 12.8 3.9 0.22 11.3 2.3 1.9 1 1 1 2 2 2 0 Putative zinc ribbon domain zinc_ribbon_2 PF13240.1 KFM00697.1 - 0.084 12.3 1.7 9.4 5.8 0.0 2.9 2 1 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 KFM00697.1 - 0.087 12.6 3.3 0.48 10.2 2.3 2.2 1 1 0 1 1 1 0 Double zinc ribbon Arc_trans_TRASH PF08394.5 KFM00697.1 - 0.1 12.8 0.8 0.18 11.9 0.6 1.5 1 0 0 1 1 1 0 Archaeal TRASH domain C1_1 PF00130.17 KFM00697.1 - 0.25 11.1 3.5 0.5 10.1 1.8 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF678 PF05077.7 KFM00697.1 - 0.31 11.0 7.6 0.18 11.8 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF678) RRN7 PF11781.3 KFM00697.1 - 6.9 6.2 6.5 1 8.9 0.6 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Sulfotransfer_2 PF03567.9 KFM00698.1 - 2.6e-41 141.9 0.5 3.4e-41 141.6 0.3 1.1 1 0 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.6 KFM00698.1 - 0.00032 19.4 0.0 0.00045 19.0 0.0 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_1 PF00685.22 KFM00698.1 - 0.005 16.1 0.0 0.0073 15.5 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain DUF2129 PF09902.4 KFM00698.1 - 0.21 11.4 1.7 0.41 10.4 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2129) Sep15_SelM PF08806.6 KFM00700.1 - 1.6e-14 53.3 0.0 1.7e-14 53.3 0.0 1.0 1 0 0 1 1 1 1 Sep15/SelM redox domain BAR PF03114.13 KFM00701.1 - 8.1e-66 221.8 4.6 1.1e-65 221.4 3.2 1.2 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 KFM00701.1 - 9.2e-11 41.1 0.0 2.8e-10 39.5 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain BAR_2 PF10455.4 KFM00701.1 - 1.9e-09 36.8 0.1 2.9e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking SH3_1 PF00018.23 KFM00701.1 - 6.7e-08 31.7 0.0 1.2e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFM00701.1 - 7.1e-08 31.8 0.0 1.7e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain CLCA_N PF08434.6 KFM00702.1 - 3.8e-109 363.9 0.2 5.7e-109 363.3 0.1 1.3 1 0 0 1 1 1 1 Calcium-activated chloride channel DUF1973 PF09315.6 KFM00702.1 - 6.5e-52 175.5 0.0 1.3e-51 174.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1973) VWA_2 PF13519.1 KFM00702.1 - 1e-19 71.2 0.1 1.8e-19 70.4 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KFM00702.1 - 7.7e-11 42.0 0.0 1.4e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 KFM00702.1 - 5e-08 32.7 0.1 8.6e-08 32.0 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 KFM00702.1 - 1.4e-05 24.3 0.2 2.4e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein CVNH PF08881.5 KFM00703.1 - 0.19 11.9 4.2 2 8.6 0.1 3.2 2 2 1 3 3 3 0 CVNH domain SIM_C PF06621.7 KFM00703.1 - 0.96 8.9 13.1 0.073 12.6 1.6 2.6 2 1 0 2 2 2 0 Single-minded protein C-terminus zf-HIT PF04438.11 KFM00704.1 - 4.2e-05 23.1 12.5 4.2e-05 23.1 8.7 2.0 3 0 0 3 3 3 1 HIT zinc finger zf-B_box PF00643.19 KFM00704.1 - 0.63 9.9 8.7 1.6 8.6 6.0 1.7 1 0 0 1 1 1 0 B-box zinc finger Cys_knot PF00007.17 KFM00705.1 - 1.2e-16 60.6 13.6 1.2e-16 60.6 9.4 3.2 4 0 0 4 4 4 1 Cystine-knot domain VWC PF00093.13 KFM00705.1 - 2e-10 40.5 12.4 2e-10 40.5 8.6 5.0 3 1 1 4 4 4 1 von Willebrand factor type C domain TSP_1 PF00090.14 KFM00705.1 - 3.1e-09 36.7 8.0 3.1e-09 36.7 5.5 3.7 5 1 0 5 5 5 1 Thrombospondin type 1 domain Sclerostin PF05463.6 KFM00705.1 - 0.00028 20.4 5.9 0.00051 19.5 4.1 1.5 1 0 0 1 1 1 1 Sclerostin (SOST) Amidinotransf PF02274.12 KFM00706.1 - 3.9e-21 75.3 0.0 4.6e-21 75.1 0.0 1.0 1 0 0 1 1 1 1 Amidinotransferase CARD PF00619.16 KFM00707.1 - 1.9e-16 59.6 0.3 2.8e-16 59.1 0.2 1.2 1 0 0 1 1 1 1 Caspase recruitment domain RhoGAP PF00620.22 KFM00708.1 - 1e-47 161.5 0.1 2.1e-47 160.5 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain WD40 PF00400.27 KFM00709.1 - 2.2e-11 43.1 5.0 0.00026 20.7 0.1 4.9 4 1 0 4 4 4 4 WD domain, G-beta repeat PKD_channel PF08016.7 KFM00710.1 - 3e-11 42.3 13.4 5.8e-11 41.4 9.3 1.4 1 0 0 1 1 1 1 Polycystin cation channel PKD_channel PF08016.7 KFM00711.1 - 3.5e-11 42.1 9.5 6.2e-11 41.3 6.6 1.3 1 0 0 1 1 1 1 Polycystin cation channel DUF4522 PF15022.1 KFM00711.1 - 0.0084 15.8 0.0 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4522) ATG27 PF09451.5 KFM00711.1 - 0.023 13.9 0.3 0.055 12.6 0.2 1.6 1 0 0 1 1 1 0 Autophagy-related protein 27 Ion_trans PF00520.26 KFM00711.1 - 1 8.5 19.5 2.7 7.2 13.5 1.8 1 1 0 1 1 1 0 Ion transport protein 7tm_1 PF00001.16 KFM00712.1 - 6e-36 123.8 24.7 9.2e-36 123.2 17.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Vitellogenin_N PF01347.17 KFM00713.1 - 3e-158 527.8 0.0 3e-158 527.8 0.0 1.7 2 0 0 2 2 2 1 Lipoprotein amino terminal region DUF1943 PF09172.6 KFM00713.1 - 2.5e-66 223.6 0.0 2.5e-66 223.6 0.0 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF1943) DUF1944 PF09175.5 KFM00713.1 - 2.8e-56 189.6 0.0 5.1e-56 188.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1944) VWD PF00094.20 KFM00713.1 - 3.5e-28 98.7 0.5 1.1e-27 97.1 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type D domain HEAT_2 PF13646.1 KFM00713.1 - 4.6e-05 23.6 0.1 0.02 15.1 0.0 2.8 2 0 0 2 2 2 1 HEAT repeats Herpes_pp85 PF04637.7 KFM00713.1 - 0.011 14.1 9.4 0.018 13.3 6.5 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) MIP-T3 PF10243.4 KFM00713.1 - 0.038 12.4 26.3 0.059 11.8 18.2 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 TonB_C PF03544.9 KFM00713.1 - 0.046 13.9 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Gram-negative bacterial TonB protein C-terminal Glyco_hydro_18 PF00704.23 KFM00714.1 - 7.6e-43 147.2 0.3 1e-42 146.8 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 TINF2_N PF14973.1 KFM00715.1 - 0.093 12.8 7.1 0.091 12.8 3.3 2.2 1 1 0 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus FliJ PF02050.11 KFM00715.1 - 5.1 7.1 19.6 0.067 13.2 0.7 3.2 2 1 1 3 3 3 0 Flagellar FliJ protein G-gamma PF00631.17 KFM00716.1 - 2.9e-09 36.5 0.0 3.1e-09 36.4 0.0 1.0 1 0 0 1 1 1 1 GGL domain Brix PF04427.13 KFM00717.1 - 5.5e-45 153.3 1.4 6.8e-45 153.0 1.0 1.1 1 0 0 1 1 1 1 Brix domain DNase_II PF03265.10 KFM00718.1 - 2.4e-111 371.8 0.1 2.7e-111 371.6 0.1 1.0 1 0 0 1 1 1 1 Deoxyribonuclease II Uricase PF01014.13 KFM00719.1 - 9.3e-51 171.5 0.0 9.7e-28 96.9 0.0 2.0 2 0 0 2 2 2 2 Uricase FolB PF02152.13 KFM00719.1 - 0.11 12.7 0.1 1 9.5 0.0 2.0 2 0 0 2 2 2 0 Dihydroneopterin aldolase SAM_1 PF00536.25 KFM00720.1 - 1.4e-09 37.9 0.0 1.7e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFM00720.1 - 4.9e-05 23.0 0.0 6.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 KFM00720.1 - 6.9e-05 22.5 0.0 7.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Pkinase PF00069.20 KFM00721.1 - 4.5e-70 235.7 0.0 5.7e-70 235.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM00721.1 - 9.6e-35 119.8 0.0 1.3e-34 119.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM00721.1 - 6e-09 35.2 0.0 1.9e-08 33.6 0.0 1.8 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 KFM00721.1 - 0.05 13.3 0.1 0.71 9.5 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family TTL PF03133.10 KFM00722.1 - 1.1e-79 267.4 0.2 1.1e-79 267.4 0.1 1.9 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 KFM00722.1 - 8.5e-07 28.0 0.1 0.0041 15.9 0.0 3.0 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 KFM00722.1 - 0.00021 21.0 0.0 0.00048 19.9 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KFM00722.1 - 0.00078 19.3 0.0 0.0037 17.1 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KFM00722.1 - 0.0029 16.4 0.0 0.026 13.2 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATPgrasp_ST PF14397.1 KFM00722.1 - 0.021 13.9 0.0 0.52 9.3 0.0 2.4 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp RimK PF08443.6 KFM00722.1 - 0.041 13.3 0.0 0.29 10.5 0.0 2.1 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Neuromodulin PF06614.6 KFM00724.1 - 1.1e-68 230.6 66.9 1.1e-68 230.6 46.4 1.7 2 0 0 2 2 2 1 Neuromodulin Neuromodulin_N PF10580.4 KFM00724.1 - 4e-12 45.5 5.1 4e-12 45.5 3.5 2.3 2 1 0 2 2 2 1 Gap junction protein N-terminal region IQ PF00612.22 KFM00724.1 - 2.6e-06 26.5 0.4 4.2e-06 25.9 0.3 1.4 1 0 0 1 1 1 1 IQ calmodulin-binding motif I-set PF07679.11 KFM00725.1 - 5.2e-40 135.2 1.5 4.4e-16 58.5 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM00725.1 - 1e-31 108.8 1.4 5.3e-13 48.9 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 KFM00725.1 - 8.9e-22 77.3 0.6 1.6e-09 38.1 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.20 KFM00725.1 - 4.6e-20 71.5 0.2 4e-08 33.2 0.0 3.5 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 KFM00725.1 - 1.9e-15 56.7 2.3 0.00049 19.9 0.1 4.7 2 2 1 3 3 3 3 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM00725.1 - 3.2e-07 30.1 1.5 0.017 14.9 0.0 2.7 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain V-set_CD47 PF08204.6 KFM00725.1 - 0.00014 21.6 0.7 0.24 11.1 0.1 3.2 2 1 1 3 3 3 2 CD47 immunoglobulin-like domain Sp38 PF07354.7 KFM00725.1 - 0.039 12.5 0.2 0.13 10.8 0.0 1.9 3 0 0 3 3 3 0 Zona-pellucida-binding protein (Sp38) C2-set PF05790.10 KFM00725.1 - 0.048 13.6 0.1 16 5.5 0.0 3.7 4 0 0 4 4 4 0 Immunoglobulin C2-set domain Yae1_N PF09811.4 KFM00726.1 - 9.9e-08 31.3 40.0 64 3.1 23.3 4.5 2 1 0 2 2 2 1 Essential protein Yae1, N terminal V-set PF07686.12 KFM00727.1 - 2.8e-18 65.8 0.7 4.9e-14 52.1 0.0 4.2 1 1 3 4 4 4 1 Immunoglobulin V-set domain Ig_2 PF13895.1 KFM00727.1 - 8.8e-16 57.8 4.8 4.1e-09 36.4 0.2 3.6 3 1 0 3 3 3 2 Immunoglobulin domain Ig_3 PF13927.1 KFM00727.1 - 3.6e-12 46.5 6.5 4e-09 36.8 0.2 3.6 3 1 0 3 3 3 2 Immunoglobulin domain I-set PF07679.11 KFM00727.1 - 3.9e-12 45.8 0.1 1.1e-05 25.1 0.0 2.9 2 1 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.20 KFM00727.1 - 1e-11 44.7 2.3 4.8e-05 23.3 0.1 3.8 2 1 0 2 2 2 2 Immunoglobulin domain FAM163 PF15069.1 KFM00727.1 - 0.025 15.1 0.0 0.067 13.7 0.0 1.7 1 1 0 1 1 1 0 FAM163 family EphA2_TM PF14575.1 KFM00727.1 - 0.049 14.0 0.1 0.11 12.9 0.1 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3619 PF12279.3 KFM00727.1 - 0.064 13.3 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) RIIa PF02197.12 KFM00728.1 - 0.075 12.4 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit Tetraspannin PF00335.15 KFM00729.1 - 4.8e-31 107.7 10.4 9.9e-31 106.7 7.2 1.4 1 1 0 1 1 1 1 Tetraspanin family YrvL PF14184.1 KFM00729.1 - 0.0049 16.6 0.9 0.0049 16.6 0.6 1.7 2 0 0 2 2 2 1 Regulatory protein YrvL RasGEF_N PF00618.15 KFM00729.1 - 0.026 14.6 0.0 0.039 14.0 0.0 1.3 1 0 0 1 1 1 0 RasGEF N-terminal motif RhoGAP PF00620.22 KFM00730.1 - 8.3e-32 109.9 0.4 1.7e-31 108.9 0.3 1.5 1 0 0 1 1 1 1 RhoGAP domain Glyco_transf_43 PF03360.11 KFM00731.1 - 1e-76 257.1 0.0 1.2e-76 256.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 43 Glyco_transf_7N PF13733.1 KFM00732.1 - 5.9e-54 181.1 0.3 8.5e-54 180.6 0.2 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.9 KFM00732.1 - 1.3e-27 95.0 0.5 3.7e-27 93.6 0.3 1.8 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFM00732.1 - 5.7e-09 35.4 0.0 2.7e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Amidase PF01425.16 KFM00733.1 - 1.8e-90 303.9 0.0 2.2e-90 303.6 0.0 1.0 1 0 0 1 1 1 1 Amidase SNF2_N PF00176.18 KFM00734.1 - 2.5e-68 230.0 0.1 4e-68 229.3 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFM00734.1 - 2.5e-12 46.4 0.0 5.9e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFM00734.1 - 2.6e-09 37.1 0.2 1.7e-08 34.5 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KFM00734.1 - 9.8e-06 25.1 0.0 1.8e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 KFM00734.1 - 5e-05 22.2 0.0 0.00016 20.5 0.0 1.8 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.1 KFM00734.1 - 0.00058 20.0 0.9 0.006 16.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain YjcZ PF13990.1 KFM00734.1 - 0.01 14.9 4.4 0.017 14.2 3.0 1.3 1 0 0 1 1 1 0 YjcZ-like protein TT_ORF2 PF02957.10 KFM00734.1 - 0.031 14.9 2.7 0.07 13.8 1.9 1.5 1 0 0 1 1 1 0 TT viral ORF2 FKBP_N PF01346.13 KFM00734.1 - 0.31 11.0 5.5 0.75 9.8 3.8 1.6 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Strabismus PF06638.6 KFM00735.1 - 5.9e-267 885.8 0.2 6.9e-267 885.6 0.1 1.0 1 0 0 1 1 1 1 Strabismus protein Virul_fac_BrkB PF03631.10 KFM00735.1 - 0.025 13.9 9.1 0.011 15.1 4.6 1.5 2 0 0 2 2 2 0 Virulence factor BrkB Calsequestrin PF01216.12 KFM00736.1 - 1e-210 699.3 45.5 5.3e-210 696.9 31.6 1.9 1 1 0 1 1 1 1 Calsequestrin Thioredoxin_6 PF13848.1 KFM00736.1 - 9e-22 77.7 2.7 1.9e-19 70.1 1.6 2.3 2 0 0 2 2 2 2 Thioredoxin-like domain Nop14 PF04147.7 KFM00736.1 - 2.5 5.9 18.4 3.5 5.4 12.8 1.3 1 0 0 1 1 1 0 Nop14-like family Sugar_tr PF00083.19 KFM00737.1 - 2.7e-30 105.3 16.8 3.9e-30 104.8 11.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFM00737.1 - 4.2e-30 104.6 48.7 1.8e-24 86.1 22.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Mab-21 PF03281.9 KFM00738.1 - 5.6e-46 156.9 1.0 8.1e-46 156.4 0.7 1.2 1 0 0 1 1 1 1 Mab-21 protein Mab-21 PF03281.9 KFM00739.1 - 6.3e-70 235.6 6.8 7e-70 235.4 4.7 1.0 1 0 0 1 1 1 1 Mab-21 protein MAR_sialic_bdg PF10564.4 KFM00739.1 - 0.078 12.7 0.5 0.25 11.1 0.1 2.1 2 1 0 2 2 2 0 Sialic-acid binding micronemal adhesive repeat E1-E2_ATPase PF00122.15 KFM00740.1 - 6.3e-61 205.3 1.7 1.1e-60 204.5 1.1 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFM00740.1 - 2.7e-44 150.8 0.3 2.7e-44 150.8 0.2 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFM00740.1 - 3.3e-31 109.3 0.0 2.5e-30 106.5 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFM00740.1 - 3.1e-26 91.1 0.0 1.1e-25 89.3 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KFM00740.1 - 1.2e-18 66.2 0.0 2.4e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KFM00740.1 - 5.7e-15 55.9 0.0 1.9e-14 54.2 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFM00740.1 - 4.7e-06 26.3 0.9 0.00081 19.0 0.4 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Sdh_cyt PF01127.17 KFM00740.1 - 0.0011 18.7 0.7 2.6 7.9 0.9 2.5 2 0 0 2 2 2 2 Succinate dehydrogenase/Fumarate reductase transmembrane subunit YuiB PF14068.1 KFM00740.1 - 0.23 11.8 4.3 0.15 12.3 0.8 2.4 2 0 0 2 2 2 0 Putative membrane protein G3P_acyltransf PF02660.10 KFM00740.1 - 1.1 8.8 8.4 0.33 10.5 3.3 1.9 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase V-set PF07686.12 KFM00741.1 - 1.1e-06 28.5 0.3 5.5e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin V-set domain Ig_2 PF13895.1 KFM00741.1 - 6.3e-06 26.2 0.5 0.076 13.1 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 KFM00741.1 - 2.8e-05 24.1 1.0 0.018 15.1 0.1 2.5 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 KFM00741.1 - 9e-05 22.2 0.2 0.0049 16.6 0.0 2.3 2 1 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.1 KFM00741.1 - 0.00022 21.6 1.6 0.012 16.1 0.2 2.7 2 2 0 2 2 2 1 Immunoglobulin domain Receptor_2B4 PF11465.3 KFM00741.1 - 0.052 13.4 0.3 0.38 10.6 0.0 2.2 2 1 0 2 2 2 0 Natural killer cell receptor 2B4 DUF4595 PF15283.1 KFM00741.1 - 0.08 12.5 0.4 0.16 11.6 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4595) with porin-like fold Lipase PF00151.14 KFM00742.1 - 2.1e-92 309.9 0.0 2.5e-92 309.6 0.0 1.1 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.2 KFM00742.1 - 6.3e-06 26.2 0.8 8.4e-06 25.8 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFM00742.1 - 0.018 14.8 0.2 0.025 14.3 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KFM00742.1 - 0.099 12.2 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Popeye PF04831.8 KFM00743.1 - 6.3e-74 246.8 0.1 9e-74 246.3 0.1 1.2 1 0 0 1 1 1 1 Popeye protein conserved region cNMP_binding PF00027.24 KFM00743.1 - 0.00014 21.6 0.1 0.00045 19.9 0.0 1.9 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain CAP_N PF01213.14 KFM00743.1 - 5.9 6.0 7.0 8.9 5.4 4.8 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PaaSYMP PF14738.1 KFM00744.1 - 2.3e-59 199.5 8.6 2.3e-59 199.5 6.0 3.8 3 1 0 3 3 3 1 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 Pkinase PF00069.20 KFM00745.1 - 1e-64 218.2 0.0 1.2e-64 218.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM00745.1 - 2.8e-24 85.5 0.0 3.8e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM00745.1 - 5e-06 25.6 0.0 4.5e-05 22.5 0.0 1.9 1 1 0 2 2 2 1 Kinase-like APH PF01636.18 KFM00745.1 - 0.0038 16.9 0.0 0.0095 15.6 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFM00745.1 - 0.047 13.2 0.0 0.061 12.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF3490 PF11995.3 KFM00745.1 - 0.12 11.9 0.1 0.19 11.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3490) 7tm_3 PF00003.17 KFM00746.1 - 6.3e-21 74.8 16.9 8.6e-21 74.3 11.7 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Sec2p PF06428.6 KFM00746.1 - 0.12 12.2 0.2 0.23 11.3 0.1 1.3 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Kazal_2 PF07648.10 KFM00748.1 - 3.8e-13 49.1 4.3 3.8e-13 49.1 3.0 2.8 3 0 0 3 3 3 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 KFM00748.1 - 9.9e-09 35.0 10.5 9.9e-09 35.0 7.3 2.6 2 1 0 2 2 2 1 Kazal-type serine protease inhibitor domain FOLN PF09289.5 KFM00748.1 - 2.9e-06 26.9 2.0 2.9e-06 26.9 1.4 2.4 2 0 0 2 2 2 1 Follistatin/Osteonectin-like EGF domain EF-hand_7 PF13499.1 KFM00748.1 - 7.6e-05 22.7 3.0 0.00044 20.3 0.5 2.8 2 1 0 2 2 2 1 EF-hand domain pair Pacifastin_I PF05375.8 KFM00748.1 - 0.00049 19.5 9.1 0.00049 19.5 6.3 3.0 3 1 0 3 3 3 1 Pacifastin inhibitor (LCMII) EF-hand_1 PF00036.27 KFM00748.1 - 0.00088 18.4 0.7 0.06 12.6 0.0 2.8 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 KFM00748.1 - 0.082 12.8 0.4 7.8 6.6 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain Hormone_3 PF00159.13 KFM00748.1 - 0.18 11.8 0.4 0.36 10.8 0.3 1.5 1 0 0 1 1 1 0 Pancreatic hormone peptide EF-hand_8 PF13833.1 KFM00748.1 - 0.2 11.2 0.7 0.87 9.2 0.0 2.3 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_like PF09279.6 KFM00748.1 - 0.43 10.6 4.1 11 6.0 0.6 2.6 2 1 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like NDUF_B4 PF07225.7 KFM00749.1 - 1.1e-27 96.3 0.1 1.2e-27 96.2 0.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) HgmA PF04209.8 KFM00750.1 - 6.7e-206 683.6 0.0 7.5e-206 683.4 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Ras PF00071.17 KFM00751.1 - 5.3e-09 35.6 0.0 2e-08 33.8 0.0 1.8 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KFM00751.1 - 2.2e-07 31.3 0.0 1.3e-05 25.6 0.0 2.2 1 1 1 2 2 2 1 Miro-like protein Arf PF00025.16 KFM00751.1 - 0.1 11.8 0.1 0.34 10.1 0.0 1.9 1 1 0 1 1 1 0 ADP-ribosylation factor family Yae1_N PF09811.4 KFM00752.1 - 2.7e-13 49.2 2.3 4.1e-13 48.6 1.6 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal DUF2385 PF09539.5 KFM00752.1 - 0.021 15.1 0.1 0.095 13.0 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2385) Ras PF00071.17 KFM00753.1 - 1.4e-55 187.1 0.3 1.7e-55 186.8 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM00753.1 - 6.7e-15 55.6 0.1 1.6e-14 54.4 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFM00753.1 - 1.7e-10 40.4 0.0 2.1e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFM00753.1 - 1.7e-05 24.3 0.1 7.2e-05 22.2 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFM00753.1 - 0.0021 17.9 0.0 0.0039 17.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KFM00753.1 - 0.0041 16.3 0.1 0.15 11.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 KFM00753.1 - 0.0058 16.0 0.2 0.018 14.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain Septin PF00735.13 KFM00753.1 - 0.015 14.3 0.1 1.6 7.6 0.0 2.2 2 0 0 2 2 2 0 Septin ArgK PF03308.11 KFM00753.1 - 0.09 11.5 0.4 0.97 8.1 0.2 2.0 2 0 0 2 2 2 0 ArgK protein Pkinase PF00069.20 KFM00754.1 - 2.4e-73 246.4 0.0 4.4e-73 245.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM00754.1 - 7.6e-36 123.5 0.0 1.2e-35 122.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM00754.1 - 2.4e-05 23.4 0.0 0.00023 20.2 0.0 2.3 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFM00754.1 - 0.016 14.2 0.0 0.032 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFM00754.1 - 0.14 11.8 0.5 8.3 6.0 0.0 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family CoA_transf_3 PF02515.12 KFM00755.1 - 3e-52 176.6 0.1 3.5e-52 176.4 0.1 1.1 1 0 0 1 1 1 1 CoA-transferase family III TGF_beta PF00019.15 KFM00756.1 - 1.1e-37 128.4 1.3 2.1e-37 127.5 0.9 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.13 KFM00756.1 - 2.6e-17 62.9 0.1 5.1e-17 61.9 0.1 1.4 1 1 0 1 1 1 1 TGF-beta propeptide zf-C2H2 PF00096.21 KFM00758.1 - 1.2e-18 66.2 30.2 0.00063 19.9 0.3 5.7 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM00758.1 - 2.6e-15 55.8 30.7 3.2e-07 30.3 1.0 5.7 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM00758.1 - 2.7e-08 33.5 29.6 0.022 15.0 0.1 5.9 5 0 0 5 5 5 4 C2H2-type zinc finger FLYWCH_N PF15423.1 KFM00759.1 - 1.1 9.4 6.9 8.4 6.6 0.3 2.1 1 1 1 2 2 2 0 FLYWCH-type zinc finger-containing protein NESP55 PF06390.7 KFM00759.1 - 1.4 8.2 8.0 1.6 8.0 5.6 1.1 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) PT PF04886.7 KFM00759.1 - 3.8 6.9 13.9 2.2 7.6 5.1 2.4 2 0 0 2 2 2 0 PT repeat DUF1308 PF07000.6 KFM00760.1 - 3.4e-119 397.7 0.1 3.9e-119 397.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) Proteasome PF00227.21 KFM00761.1 - 6.2e-60 201.7 0.0 8.2e-60 201.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KFM00761.1 - 7.2e-07 28.4 0.1 1.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PBP_dimer PF03717.10 KFM00761.1 - 0.014 15.4 0.0 2.4 8.1 0.0 2.1 2 0 0 2 2 2 0 Penicillin-binding Protein dimerisation domain Ribosomal_L32p PF01783.18 KFM00762.1 - 1.2e-08 34.9 6.9 1.9e-08 34.3 4.8 1.3 1 0 0 1 1 1 1 Ribosomal L32p protein family RecR PF02132.10 KFM00762.1 - 0.0013 18.1 0.6 0.0023 17.3 0.4 1.4 1 0 0 1 1 1 1 RecR protein DZR PF12773.2 KFM00762.1 - 0.019 14.7 1.8 0.041 13.7 1.2 1.5 1 0 0 1 1 1 0 Double zinc ribbon NRDD PF13597.1 KFM00762.1 - 0.18 9.8 1.4 0.23 9.4 1.0 1.1 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase HECT PF00632.20 KFM00764.1 - 2.4e-93 312.7 0.0 3.6e-93 312.1 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 KFM00764.1 - 5.4e-17 61.3 0.4 1.6e-09 37.4 0.4 2.7 2 0 0 2 2 2 2 WW domain C2 PF00168.25 KFM00764.1 - 2.1e-09 37.1 0.0 4.6e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain Keratin_B2_2 PF13885.1 KFM00764.1 - 0.23 11.2 22.3 0.73 9.6 15.5 1.9 1 0 0 1 1 1 0 Keratin, high sulfur B2 protein RFXA_RFXANK_bdg PF15289.1 KFM00764.1 - 0.96 9.6 4.0 0.61 10.2 0.0 2.6 3 0 0 3 3 3 0 Regulatory factor X-associated C-terminal binding domain Biliv-reduc_cat PF09166.5 KFM00766.1 - 1e-54 183.4 0.1 1.7e-54 182.7 0.1 1.3 1 0 0 1 1 1 1 Biliverdin reductase, catalytic GFO_IDH_MocA PF01408.17 KFM00766.1 - 3.7e-17 62.9 0.2 8.9e-17 61.7 0.1 1.7 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold WBP-1 PF11669.3 KFM00767.1 - 0.0002 21.3 2.3 0.0002 21.3 1.6 2.2 2 0 0 2 2 2 1 WW domain-binding protein 1 DUF3483 PF11982.3 KFM00767.1 - 0.058 12.6 0.0 0.081 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3483) TMEM52 PF14979.1 KFM00767.1 - 1.7 8.5 16.1 51 3.7 11.1 2.1 1 1 0 1 1 1 0 Transmembrane 52 CX PF01705.14 KFM00767.1 - 8 6.5 8.3 17 5.4 5.7 1.6 1 0 0 1 1 1 0 CX module LANC_like PF05147.8 KFM00768.1 - 1.8e-89 299.8 0.1 2.1e-89 299.6 0.1 1.0 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein C5-epim_C PF06662.8 KFM00768.1 - 0.0011 18.2 0.2 0.74 9.0 0.0 3.1 3 0 0 3 3 3 2 D-glucuronyl C5-epimerase C-terminus TPR_12 PF13424.1 KFM00768.1 - 0.013 15.4 0.9 2.1 8.3 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1680 PF07944.7 KFM00768.1 - 0.035 12.3 0.7 1.1 7.3 0.1 2.6 2 2 0 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) Pkinase_Tyr PF07714.12 KFM00769.1 - 1.8e-88 295.9 0.0 2.6e-88 295.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Recep_L_domain PF01030.19 KFM00769.1 - 2.7e-59 198.0 3.2 1.6e-29 102.1 1.6 2.5 2 0 0 2 2 2 2 Receptor L domain GF_recep_IV PF14843.1 KFM00769.1 - 2.1e-54 182.6 80.8 4.5e-47 158.9 17.6 4.1 2 1 2 4 4 4 2 Growth factor receptor domain IV Pkinase PF00069.20 KFM00769.1 - 5.2e-43 147.0 0.0 8.4e-43 146.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Furin-like PF00757.15 KFM00769.1 - 1.5e-35 122.0 88.9 3.5e-30 104.6 29.5 4.2 2 1 2 4 4 4 3 Furin-like cysteine rich region APH PF01636.18 KFM00769.1 - 0.0097 15.6 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KFM00769.1 - 0.1 11.5 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like SecE PF00584.15 KFM00770.1 - 1.7e-15 56.3 0.1 2.1e-15 56.0 0.1 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex TPK_catalytic PF04263.11 KFM00771.1 - 1.5e-31 108.5 0.0 2.7e-31 107.7 0.0 1.4 2 0 0 2 2 2 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 KFM00771.1 - 2.2e-23 81.7 0.4 3.4e-23 81.1 0.3 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain F5_F8_type_C PF00754.20 KFM00772.1 - 4.2e-17 62.2 2.3 4.6e-17 62.0 1.6 1.0 1 0 0 1 1 1 1 F5/8 type C domain Laminin_G_2 PF02210.19 KFM00773.1 - 1.7e-24 86.2 0.2 2e-18 66.6 0.1 2.1 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.18 KFM00773.1 - 1.6e-15 57.2 0.0 3.8e-11 43.1 0.0 2.1 2 0 0 2 2 2 2 Laminin G domain DUF4154 PF13689.1 KFM00773.1 - 0.088 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4154) Laminin_G_2 PF02210.19 KFM00774.1 - 1.2e-49 167.6 0.1 1.9e-23 82.9 0.0 2.3 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.18 KFM00774.1 - 4.4e-30 104.3 0.0 1.2e-13 51.1 0.0 2.5 2 1 0 2 2 2 2 Laminin G domain Laminin_G_3 PF13385.1 KFM00774.1 - 9.6e-05 22.6 0.0 0.0084 16.3 0.0 2.6 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Syndecan PF01034.15 KFM00774.1 - 0.069 12.8 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Cullin PF00888.17 KFM00775.1 - 2.6e-205 683.4 25.1 3.3e-205 683.0 17.4 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KFM00775.1 - 5.2e-28 96.6 2.7 5.2e-28 96.6 1.9 2.3 3 0 0 3 3 3 1 Cullin protein neddylation domain SET PF00856.23 KFM00776.1 - 1.3e-22 80.7 0.6 1.3e-22 80.7 0.4 2.9 2 2 0 2 2 2 1 SET domain EZH2_WD-Binding PF11616.3 KFM00776.1 - 5.9e-19 67.6 4.3 1.3e-18 66.4 3.0 1.6 1 0 0 1 1 1 1 WD repeat binding protein EZH2 Thioredoxin PF00085.15 KFM00778.1 - 3.2e-98 322.3 0.6 1.9e-31 107.8 0.0 3.3 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.1 KFM00778.1 - 2.4e-28 99.1 8.3 1.6e-19 70.4 0.6 4.9 4 1 0 4 4 4 4 Thioredoxin-like domain Thioredoxin_2 PF13098.1 KFM00778.1 - 2.1e-21 76.2 6.7 4.9e-06 26.7 0.0 5.2 4 3 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KFM00778.1 - 5.5e-21 74.4 3.6 3.2e-05 23.9 0.0 6.4 4 2 2 6 6 6 3 Thioredoxin-like Thioredoxin_7 PF13899.1 KFM00778.1 - 6.4e-15 54.9 0.0 0.00042 20.2 0.0 3.8 3 0 0 3 3 3 3 Thioredoxin-like Calsequestrin PF01216.12 KFM00778.1 - 1.2e-11 44.0 0.1 1.2e-11 44.0 0.0 3.2 2 2 2 4 4 3 2 Calsequestrin AhpC-TSA PF00578.16 KFM00778.1 - 2.8e-10 39.9 0.6 0.03 13.9 0.0 3.9 3 1 0 3 3 3 3 AhpC/TSA family Thioredoxin_4 PF13462.1 KFM00778.1 - 4.1e-08 33.4 1.7 0.28 11.1 0.0 5.0 5 0 0 5 5 5 3 Thioredoxin Redoxin PF08534.5 KFM00778.1 - 4.1e-08 32.8 1.6 0.16 11.4 0.0 3.8 4 0 0 4 4 4 3 Redoxin HyaE PF07449.6 KFM00778.1 - 0.00016 21.5 0.0 3.9 7.4 0.0 3.9 4 0 0 4 4 4 1 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.1 KFM00778.1 - 0.00031 20.3 0.1 0.77 9.3 0.0 3.5 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_3 PF13192.1 KFM00778.1 - 0.0017 18.1 0.1 2.3 8.0 0.0 3.3 3 0 0 3 3 3 1 Thioredoxin domain TraF PF13728.1 KFM00778.1 - 0.0045 16.4 0.0 0.9 8.9 0.0 3.2 3 0 0 3 3 3 1 F plasmid transfer operon protein Omp28 PF11551.3 KFM00778.1 - 0.0055 16.2 0.0 3.6 7.0 0.0 3.2 3 0 0 3 3 3 1 Outer membrane protein Omp28 DSBA PF01323.15 KFM00778.1 - 0.015 14.8 1.8 30 4.1 0.0 4.8 3 3 2 5 5 5 0 DSBA-like thioredoxin domain Thioredoxin_5 PF13743.1 KFM00778.1 - 0.23 10.9 2.7 30 4.0 0.0 4.6 4 1 1 5 5 5 0 Thioredoxin Mu-like_Com PF10122.4 KFM00778.1 - 0.5 9.4 5.1 16 4.6 0.1 3.3 3 0 0 3 3 3 0 Mu-like prophage protein Com Sigma70_ner PF04546.8 KFM00778.1 - 9.7 5.7 9.1 21 4.6 6.3 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Gag_p30 PF02093.11 KFM00779.1 - 5.2e-22 78.1 0.1 6.2e-22 77.8 0.1 1.0 1 0 0 1 1 1 1 Gag P30 core shell protein Gag_p24 PF00607.15 KFM00779.1 - 0.00016 21.2 0.2 0.00065 19.3 0.1 1.8 1 1 0 1 1 1 1 gag gene protein p24 (core nucleocapsid protein) GED PF02212.13 KFM00779.1 - 0.11 12.3 0.1 0.9 9.4 0.0 2.0 2 0 0 2 2 2 0 Dynamin GTPase effector domain MACPF PF01823.14 KFM00780.1 - 1.8e-06 27.8 0.0 4.8e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 MAC/Perforin domain RVT_1 PF00078.22 KFM00781.1 - 0.0096 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PLA2_B PF01735.13 KFM00783.1 - 1.4e-156 521.5 0.0 1.7e-156 521.2 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain C2 PF00168.25 KFM00783.1 - 3.4e-14 52.4 0.1 8.4e-14 51.1 0.1 1.7 1 0 0 1 1 1 1 C2 domain An_peroxidase PF03098.10 KFM00784.1 - 1.1e-99 334.2 0.0 3.1e-97 326.1 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase EGF PF00008.22 KFM00784.1 - 0.0017 18.2 12.1 0.0035 17.2 8.4 1.5 1 0 0 1 1 1 1 EGF-like domain EGF_2 PF07974.8 KFM00784.1 - 0.36 11.0 10.5 0.81 9.8 7.3 1.6 1 0 0 1 1 1 0 EGF-like domain Kinesin PF00225.18 KFM00785.1 - 2.8e-52 177.4 1.7 5.8e-52 176.4 1.2 1.5 1 0 0 1 1 1 1 Kinesin motor domain SAM_1 PF00536.25 KFM00785.1 - 0.002 18.2 0.0 0.0089 16.1 0.1 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFM00785.1 - 0.033 14.0 0.1 0.07 12.9 0.1 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) UBA PF00627.26 KFM00786.1 - 8.5e-10 38.1 1.9 5.1e-05 22.9 0.0 4.1 4 0 0 4 4 4 3 UBA/TS-N domain UBA_3 PF09288.5 KFM00786.1 - 0.0012 18.3 0.9 0.42 10.2 0.0 3.2 3 0 0 3 3 3 2 Fungal ubiquitin-associated domain RNase_T PF00929.19 KFM00786.1 - 0.12 12.6 0.2 0.25 11.6 0.2 1.7 1 1 0 1 1 1 0 Exonuclease MerR-DNA-bind PF09278.6 KFM00786.1 - 0.19 12.1 1.8 0.22 11.9 0.1 2.1 2 0 0 2 2 2 0 MerR, DNA binding WD40 PF00400.27 KFM00787.1 - 1.2e-09 37.6 1.5 2.5e-05 23.9 1.1 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat Interferon PF00143.14 KFM00788.1 - 2.2e-21 76.4 0.1 2.4e-21 76.2 0.0 1.0 1 0 0 1 1 1 1 Interferon alpha/beta domain Creb_binding PF09030.5 KFM00788.1 - 0.021 15.0 0.4 0.089 12.9 0.1 1.9 1 1 1 2 2 2 0 Creb binding HTH_Tnp_4 PF13613.1 KFM00788.1 - 0.82 9.2 0.1 0.82 9.2 0.0 2.4 3 0 0 3 3 3 0 Helix-turn-helix of DDE superfamily endonuclease UQ_con PF00179.21 KFM00789.1 - 3.6e-32 110.7 0.3 4.6e-32 110.3 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFM00789.1 - 0.059 13.1 0.1 0.3 10.8 0.1 2.1 1 1 0 1 1 1 0 Prokaryotic E2 family B Nrap PF03813.9 KFM00790.1 - 2.5e-244 813.1 0.0 3e-244 812.9 0.0 1.0 1 0 0 1 1 1 1 Nrap protein MIP PF00230.15 KFM00791.1 - 5.6e-52 176.4 13.3 7.1e-52 176.1 9.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein PLA2_inh PF02988.10 KFM00792.1 - 3.9e-20 72.0 19.1 1.2e-17 64.0 5.3 2.1 2 0 0 2 2 2 2 Phospholipase A2 inhibitor UPAR_LY6 PF00021.16 KFM00792.1 - 3.5e-11 43.3 19.0 8.8e-07 29.2 3.2 2.1 2 0 0 2 2 2 2 u-PAR/Ly-6 domain Amidase_5 PF05382.8 KFM00792.1 - 0.052 13.1 0.6 0.075 12.6 0.4 1.3 1 0 0 1 1 1 0 Bacteriophage peptidoglycan hydrolase MIP PF00230.15 KFM00793.1 - 1.9e-42 145.2 10.4 2.4e-42 144.9 7.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF3172 PF11371.3 KFM00793.1 - 0.029 13.8 0.2 0.029 13.8 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3172) RVT_1 PF00078.22 KFM00795.1 - 0.0057 16.0 0.0 0.0096 15.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RRM_1 PF00076.17 KFM00797.1 - 3.5e-37 125.8 0.0 2.2e-17 62.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM00797.1 - 3.1e-27 94.3 0.1 1.1e-12 47.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM00797.1 - 2.8e-23 81.5 0.2 3e-10 39.7 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 KFM00797.1 - 0.00039 20.3 0.0 0.36 10.8 0.0 2.6 2 0 0 2 2 2 2 RNA binding domain RRM_3 PF08777.6 KFM00797.1 - 0.0098 15.7 0.0 3 7.7 0.0 2.4 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 KFM00797.1 - 0.013 15.2 0.0 0.061 13.1 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.17 KFM00798.1 - 2.2e-16 59.2 0.0 3.2e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM00798.1 - 7e-09 35.5 0.0 1.1e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM00798.1 - 3.7e-06 26.6 0.0 6e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EMI PF07546.8 KFM00800.1 - 1.7e-25 89.2 11.1 2.4e-25 88.7 7.7 1.2 1 0 0 1 1 1 1 EMI domain Collagen PF01391.13 KFM00800.1 - 7.8e-19 66.9 80.4 1.9e-09 36.9 24.9 3.9 3 1 0 3 3 3 2 Collagen triple helix repeat (20 copies) DUF2360 PF10152.4 KFM00800.1 - 0.093 13.0 0.0 0.4 10.9 0.0 1.9 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) PspB PF06667.7 KFM00800.1 - 0.15 11.9 0.6 9.6 6.2 0.0 2.7 3 0 0 3 3 3 0 Phage shock protein B EF-hand_1 PF00036.27 KFM00801.1 - 9.2e-10 37.1 1.8 4.9e-06 25.4 0.6 3.1 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 KFM00801.1 - 8e-08 32.3 0.4 1.2e-06 28.4 0.3 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 KFM00801.1 - 2.7e-07 30.0 1.2 0.0088 15.6 0.1 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 KFM00801.1 - 5.2e-07 29.0 0.6 2.8e-06 26.7 0.5 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 KFM00801.1 - 9.3e-05 21.5 1.6 0.00031 19.9 1.1 2.0 1 0 0 1 1 1 1 EF hand mTERF PF02536.9 KFM00801.1 - 0.008 14.7 0.2 0.0092 14.6 0.1 1.1 1 0 0 1 1 1 1 mTERF CUT PF02376.10 KFM00802.1 - 4e-89 292.5 0.3 3.6e-28 97.2 0.0 4.1 3 0 0 3 3 3 3 CUT domain Homeobox PF00046.24 KFM00802.1 - 5.1e-15 54.8 0.8 5.1e-15 54.8 0.6 2.4 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 KFM00802.1 - 1.4e-06 27.8 0.2 6.7e-06 25.7 0.2 2.2 1 0 0 1 1 1 1 Homeobox KN domain NPV_P10 PF05531.7 KFM00802.1 - 0.02 15.1 12.8 0.024 14.8 0.9 4.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein HOOK PF05622.7 KFM00802.1 - 0.021 12.6 36.7 0.049 11.4 25.4 1.6 1 0 0 1 1 1 0 HOOK protein DUF1168 PF06658.7 KFM00803.1 - 1.3e-46 157.6 22.5 1.5e-46 157.4 15.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) rRNA_processing PF08524.6 KFM00803.1 - 0.17 11.6 27.1 0.22 11.2 18.8 1.1 1 0 0 1 1 1 0 rRNA processing BPL_N PF09825.4 KFM00803.1 - 0.32 9.7 5.8 0.4 9.4 4.0 1.0 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal FLO_LFY PF01698.11 KFM00803.1 - 0.55 9.0 15.9 0.64 8.7 11.0 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF2413 PF10310.4 KFM00803.1 - 0.74 8.5 18.3 0.87 8.3 12.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Peptidase_C58 PF03543.9 KFM00803.1 - 1.5 8.2 9.8 1.8 7.9 6.8 1.2 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen GAGA_bind PF06217.7 KFM00803.1 - 3.1 7.6 13.9 3.6 7.4 9.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family MIP-T3 PF10243.4 KFM00803.1 - 4 5.7 29.6 4.8 5.5 20.5 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RNA_pol_3_Rpc31 PF11705.3 KFM00803.1 - 4.7 7.0 24.3 5.9 6.7 16.8 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DDHD PF02862.12 KFM00803.1 - 4.8 6.9 13.9 6.2 6.5 9.7 1.1 1 0 0 1 1 1 0 DDHD domain Vfa1 PF08432.5 KFM00803.1 - 7.8 6.4 23.2 13 5.7 16.1 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FAM60A PF15396.1 KFM00803.1 - 8.4 6.0 13.5 10 5.7 9.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A BTV_NS2 PF04514.7 KFM00803.1 - 8.4 5.1 20.5 10 4.9 14.2 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Orai-1 PF07856.7 KFM00804.1 - 9.9e-79 262.9 6.6 1.2e-78 262.7 4.5 1.0 1 0 0 1 1 1 1 Mediator of CRAC channel activity DUF2207 PF09972.4 KFM00804.1 - 0.23 9.9 0.8 0.34 9.4 0.6 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) zf-LITAF-like PF10601.4 KFM00804.1 - 0.27 11.1 6.0 3.5 7.5 0.0 3.2 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain zf-DHHC PF01529.15 KFM00804.1 - 1.8 7.9 3.8 6.4 6.1 2.6 1.8 1 1 0 1 1 1 0 DHHC palmitoyltransferase 2OG-FeII_Oxy_2 PF13532.1 KFM00805.1 - 3.9e-05 23.5 0.0 5.3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KFM00805.1 - 0.00031 20.9 0.0 0.0041 17.3 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily LRR_8 PF13855.1 KFM00806.1 - 1.9e-06 27.5 10.0 0.00031 20.4 2.0 2.9 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 KFM00806.1 - 4.3e-06 26.2 21.3 0.00015 21.2 1.1 3.2 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) WD40 PF00400.27 KFM00806.1 - 9.4e-06 25.3 2.6 1.4e-05 24.7 0.0 2.8 4 0 0 4 4 4 1 WD domain, G-beta repeat PQQ_2 PF13360.1 KFM00806.1 - 0.00073 19.0 0.0 0.36 10.2 0.1 2.5 2 1 0 2 2 2 2 PQQ-like domain LRR_1 PF00560.28 KFM00806.1 - 0.045 13.7 9.3 0.81 9.9 0.5 4.0 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.1 KFM00806.1 - 0.12 12.5 6.9 8.9 6.7 0.2 4.0 3 0 0 3 3 3 0 Leucine Rich repeat LRR_7 PF13504.1 KFM00806.1 - 0.64 10.4 7.4 7.7 7.1 0.1 4.0 4 0 0 4 4 4 0 Leucine rich repeat RNA_pol_L_2 PF13656.1 KFM00807.1 - 2.5e-19 68.5 0.0 2.8e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KFM00807.1 - 7.6e-06 24.9 0.0 9.3e-06 24.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain SHNi-TPR PF10516.4 KFM00807.1 - 0.058 12.6 0.1 0.33 10.2 0.0 1.9 1 1 1 2 2 2 0 SHNi-TPR RasGAP PF00616.14 KFM00808.1 - 8e-38 130.0 0.0 1.1e-37 129.6 0.0 1.2 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 KFM00808.1 - 3.1e-26 91.0 0.1 4.7e-23 80.8 0.0 2.4 2 0 0 2 2 2 2 C2 domain WWE PF02825.15 KFM00809.1 - 1.6e-31 107.4 0.1 1.6e-15 56.2 0.0 2.5 2 0 0 2 2 2 2 WWE domain zf-rbx1 PF12678.2 KFM00809.1 - 1e-05 25.5 2.2 1e-05 25.5 1.5 2.1 3 0 0 3 3 3 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KFM00809.1 - 2.2e-05 24.0 8.1 5.9e-05 22.6 5.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM00809.1 - 3.5e-05 23.5 9.0 0.00022 20.9 6.2 2.4 1 1 0 1 1 1 1 Ring finger domain zf-Apc11 PF12861.2 KFM00809.1 - 0.0073 16.1 1.6 0.03 14.1 1.1 2.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 KFM00809.1 - 0.0076 15.9 6.4 0.0076 15.9 4.5 2.0 2 1 0 2 2 2 1 zinc-RING finger domain zf-UDP PF14569.1 KFM00809.1 - 0.073 12.8 0.5 0.23 11.2 0.3 1.9 1 0 0 1 1 1 0 Zinc-binding RING-finger PHD PF00628.24 KFM00809.1 - 2.4 7.9 8.7 0.83 9.4 3.4 2.4 2 1 0 2 2 2 0 PHD-finger zf-C3HC4_2 PF13923.1 KFM00809.1 - 2.9 7.9 13.3 1.6 8.8 4.2 3.1 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SRCR PF00530.13 KFM00810.1 - 2.3e-123 403.1 40.1 8.5e-32 109.4 2.4 4.1 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 KFM00810.1 - 8.1e-20 70.8 16.3 5.4e-05 23.3 0.1 4.5 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain 14-3-3 PF00244.15 KFM00811.1 - 1.3e-99 332.0 7.7 1.5e-99 331.8 5.4 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF1987 PF09345.5 KFM00811.1 - 0.34 10.7 2.1 1.5 8.6 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF1987) TPR_11 PF13414.1 KFM00812.1 - 3.9e-21 74.4 7.0 2.2e-16 59.2 2.0 2.9 2 1 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 KFM00812.1 - 2.6e-12 45.7 15.8 2.2e-06 27.0 1.2 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFM00812.1 - 1.7e-11 43.0 11.7 1.8e-05 24.2 0.1 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFM00812.1 - 4.5e-07 30.3 0.0 0.00023 21.7 0.0 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFM00812.1 - 4.7e-07 29.6 7.8 7.9e-06 25.7 1.4 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFM00812.1 - 1.1e-06 27.9 7.0 0.00046 19.7 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat HEAT_2 PF13646.1 KFM00812.1 - 8.2e-06 26.0 2.6 0.038 14.2 0.1 4.8 4 1 1 5 5 5 2 HEAT repeats Apc3 PF12895.2 KFM00812.1 - 2.9e-05 24.1 7.3 7.1e-05 22.8 3.9 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 Arm PF00514.18 KFM00812.1 - 4.8e-05 23.0 6.9 4.6 7.2 0.2 6.3 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat TPR_19 PF14559.1 KFM00812.1 - 0.00011 22.5 1.7 0.053 13.8 0.3 3.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFM00812.1 - 0.00013 22.2 0.1 0.46 11.2 0.0 3.7 1 1 2 3 3 3 2 Tetratricopeptide repeat HEAT PF02985.17 KFM00812.1 - 0.00032 20.5 4.2 0.26 11.4 0.0 5.0 5 0 0 5 5 5 1 HEAT repeat Fis1_TPR_C PF14853.1 KFM00812.1 - 0.00093 19.0 4.7 0.16 11.8 0.1 3.5 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat HEAT_EZ PF13513.1 KFM00812.1 - 0.0044 17.4 4.5 9.5 6.8 0.0 5.0 6 0 0 6 6 4 0 HEAT-like repeat TPR_6 PF13174.1 KFM00812.1 - 0.01 16.2 1.5 0.066 13.6 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFM00812.1 - 0.017 14.8 5.2 6 6.9 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 KFM00812.1 - 0.035 14.2 4.7 0.29 11.4 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Arm_2 PF04826.8 KFM00812.1 - 0.037 13.1 1.5 1 8.4 0.2 2.9 2 0 0 2 2 2 0 Armadillo-like Vanabin-2 PF11437.3 KFM00812.1 - 4.2 7.4 9.9 2.2 8.3 1.2 2.7 2 0 0 2 2 2 0 Vanadium-binding protein 2 I-set PF07679.11 KFM00813.1 - 6.9e-77 253.3 5.8 3.3e-18 65.3 0.1 5.5 5 0 0 5 5 5 5 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM00813.1 - 1e-49 166.5 0.5 3.4e-11 43.0 0.0 5.6 5 0 0 5 5 5 5 Immunoglobulin domain Ig_3 PF13927.1 KFM00813.1 - 1.8e-37 127.6 6.7 1.5e-07 31.7 0.1 5.9 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.20 KFM00813.1 - 1.2e-36 124.5 1.9 3.4e-07 30.2 0.1 6.0 5 0 0 5 5 5 5 Immunoglobulin domain fn3 PF00041.16 KFM00813.1 - 1.4e-25 89.1 0.2 7e-13 48.5 0.0 3.0 2 0 0 2 2 2 2 Fibronectin type III domain V-set PF07686.12 KFM00813.1 - 9.9e-23 80.2 2.4 0.0013 18.6 0.0 6.2 5 0 0 5 5 5 5 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM00813.1 - 8.4e-13 48.0 2.9 0.02 14.7 0.0 5.6 6 0 0 6 6 6 3 CD80-like C2-set immunoglobulin domain C1-set PF07654.10 KFM00813.1 - 3e-08 33.5 3.2 0.0026 17.7 0.0 5.0 5 0 0 5 5 5 2 Immunoglobulin C1-set domain Receptor_2B4 PF11465.3 KFM00813.1 - 0.011 15.6 0.6 8.1 6.4 0.0 4.1 4 0 0 4 4 4 0 Natural killer cell receptor 2B4 PTPS PF01242.14 KFM00815.1 - 1.6e-32 111.7 0.0 1.9e-32 111.5 0.0 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase RPE65 PF03055.10 KFM00816.1 - 3.5e-131 438.1 0.0 4.2e-131 437.8 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein TEX12 PF15219.1 KFM00817.1 - 4e-26 90.9 0.3 4.5e-26 90.7 0.2 1.0 1 0 0 1 1 1 1 Testis-expressed 12 IL1 PF00340.14 KFM00818.1 - 3.7e-32 110.2 0.5 3.7e-32 110.2 0.4 1.4 2 0 0 2 2 2 1 Interleukin-1 / 18 Somatostatin PF03002.10 KFM00818.1 - 0.88 9.2 4.2 1.9 8.2 2.9 1.5 1 0 0 1 1 1 0 Somatostatin/Cortistatin family CybS PF05328.7 KFM00819.1 - 1.2e-36 125.2 0.3 1.4e-36 125.0 0.2 1.0 1 0 0 1 1 1 1 CybS Subtilosin_A PF11420.3 KFM00819.1 - 0.073 13.1 0.1 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 Bacteriocin subtilosin A Macoilin PF09726.4 KFM00820.1 - 0.67 8.1 33.4 0.82 7.8 23.1 1.2 1 0 0 1 1 1 0 Transmembrane protein PIH1 PF08190.7 KFM00821.1 - 1.3e-47 162.9 0.6 1.5e-47 162.6 0.4 1.0 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 CS PF04969.11 KFM00821.1 - 0.0092 16.5 3.0 0.011 16.2 0.9 2.0 2 0 0 2 2 2 1 CS domain HSP20 PF00011.16 KFM00821.1 - 0.028 14.2 0.1 0.057 13.2 0.1 1.5 1 0 0 1 1 1 0 Hsp20/alpha crystallin family CReP_N PF10472.4 KFM00821.1 - 0.043 12.5 0.1 0.059 12.0 0.1 1.2 1 0 0 1 1 1 0 eIF2-alpha phosphatase phosphorylation constitutive repressor 2-oxoacid_dh PF00198.18 KFM00822.1 - 2e-81 272.6 0.1 2.6e-81 272.2 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KFM00822.1 - 8.2e-32 108.6 1.1 2.1e-15 56.1 0.0 2.4 2 0 0 2 2 2 2 Biotin-requiring enzyme E3_binding PF02817.12 KFM00822.1 - 3.3e-19 68.2 1.1 9.8e-19 66.7 0.7 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 KFM00822.1 - 0.008 15.8 0.0 4.9 6.9 0.0 2.7 2 0 0 2 2 2 2 Biotin-lipoyl like HlyD_2 PF12700.2 KFM00822.1 - 0.18 10.9 0.0 3.9 6.5 0.0 2.3 2 0 0 2 2 2 0 HlyD family secretion protein HSP20 PF00011.16 KFM00823.1 - 5.8e-20 71.0 0.0 8.4e-20 70.5 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Crystallin PF00525.13 KFM00823.1 - 4.8e-06 26.6 0.0 9.8e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Alpha crystallin A chain, N terminal HSP20 PF00011.16 KFM00824.1 - 2.3e-28 98.0 0.1 2.9e-28 97.7 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Crystallin PF00525.13 KFM00824.1 - 2.5e-27 94.8 2.9 4e-27 94.1 2.0 1.4 1 0 0 1 1 1 1 Alpha crystallin A chain, N terminal DUF2431 PF10354.4 KFM00825.1 - 8.8e-25 87.5 0.0 1.6e-24 86.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) FDX-ACB PF03147.9 KFM00825.1 - 2e-16 59.9 0.0 4e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Methyltransf_26 PF13659.1 KFM00825.1 - 0.0038 17.2 0.0 0.0085 16.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain tRNA-synt_2d PF01409.15 KFM00825.1 - 0.0045 16.2 0.0 0.0089 15.2 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class II core domain (F) KRAB PF01352.22 KFM00826.1 - 2.7e-20 71.5 1.1 2.9e-20 71.4 0.8 1.0 1 0 0 1 1 1 1 KRAB box zf-H2C2_2 PF13465.1 KFM00827.1 - 3.2e-90 292.3 75.2 9.8e-10 38.2 0.2 12.4 12 0 0 12 12 12 12 Zinc-finger double domain zf-C2H2 PF00096.21 KFM00827.1 - 1.8e-73 238.6 89.8 1.4e-07 31.4 0.7 12.1 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM00827.1 - 6.4e-43 141.9 76.1 3.6e-05 23.7 0.1 12.1 12 0 0 12 12 12 11 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM00827.1 - 3.3e-23 80.8 79.5 0.0031 17.3 0.6 12.4 12 0 0 12 12 12 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM00827.1 - 3.9e-17 61.8 43.1 0.13 12.4 0.1 12.1 12 0 0 12 12 12 7 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM00827.1 - 7.6e-11 41.8 64.2 0.031 14.4 1.3 12.0 12 0 0 12 12 12 5 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 KFM00827.1 - 6e-08 32.5 60.4 0.076 12.9 2.0 11.1 3 1 7 11 11 11 5 Zinc ribbon domain Imm-NTF2-2 PF15631.1 KFM00827.1 - 2.3e-05 24.2 0.0 13 5.8 0.0 6.8 2 2 7 9 9 9 0 NTF2 fold immunity protein C1_4 PF07975.7 KFM00827.1 - 3.7e-05 23.6 45.1 0.86 9.6 1.0 8.4 2 1 7 9 9 9 4 TFIIH C1-like domain LIM PF00412.17 KFM00827.1 - 0.00011 22.1 57.3 2.4 8.2 2.0 10.1 4 3 5 10 10 10 2 LIM domain FYDLN_acid PF09538.5 KFM00827.1 - 0.00065 20.2 23.1 3.1 8.4 0.0 9.5 1 1 8 9 9 9 1 Protein of unknown function (FYDLN_acid) zf-UBP PF02148.14 KFM00827.1 - 0.0036 17.3 45.6 0.19 11.8 1.2 8.1 2 2 6 8 8 8 2 Zn-finger in ubiquitin-hydrolases and other protein Prok-RING_1 PF14446.1 KFM00827.1 - 0.0039 16.8 40.4 4.6 7.0 0.0 11.1 11 1 1 12 12 12 1 Prokaryotic RING finger family 1 BolA PF01722.13 KFM00827.1 - 0.0062 16.4 7.2 0.085 12.8 0.0 4.6 2 2 2 5 5 5 1 BolA-like protein DZR PF12773.2 KFM00827.1 - 0.021 14.6 50.0 1.9 8.3 2.3 7.3 1 1 4 5 5 4 0 Double zinc ribbon CpXC PF14353.1 KFM00827.1 - 0.028 14.3 42.7 2.3 8.1 0.1 10.2 5 3 3 9 9 9 0 CpXC protein zf-AN1 PF01428.11 KFM00827.1 - 0.048 13.5 65.8 0.13 12.1 0.8 11.6 10 2 1 12 12 12 0 AN1-like Zinc finger HypA PF01155.14 KFM00827.1 - 0.077 12.6 38.8 7 6.3 0.6 6.7 1 1 2 4 4 4 0 Hydrogenase expression/synthesis hypA family zf-IS66 PF13005.2 KFM00827.1 - 0.29 11.1 39.7 2.5 8.1 0.0 10.6 10 2 2 12 12 12 0 zinc-finger binding domain of transposase IS66 ADK_lid PF05191.9 KFM00827.1 - 0.52 10.0 0.0 0.52 10.0 0.0 10.1 10 2 0 10 10 10 0 Adenylate kinase, active site lid GAGA PF09237.6 KFM00827.1 - 1.1 8.8 12.3 7.4 6.2 0.0 5.3 2 2 4 6 6 6 0 GAGA factor zf-trcl PF13451.1 KFM00827.1 - 3.9 7.1 53.9 7.2 6.3 0.1 11.2 12 0 0 12 12 12 0 Probable zinc-binding domain SNF2_N PF00176.18 KFM00829.1 - 1.2e-74 250.8 1.0 2.6e-74 249.7 0.7 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.1 KFM00829.1 - 2.4e-33 114.3 0.9 2.4e-33 114.3 0.7 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4208) Chromo PF00385.19 KFM00829.1 - 5.4e-28 96.4 8.7 3.9e-16 58.4 0.0 4.4 4 0 0 4 4 4 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 KFM00829.1 - 6.2e-14 51.6 0.0 1.4e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RGM_C PF06534.8 KFM00830.1 - 8.2e-76 253.1 0.0 1.2e-75 252.6 0.0 1.2 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) C-terminus RGM_N PF06535.7 KFM00830.1 - 2.9e-67 225.7 1.9 4.1e-67 225.1 1.3 1.2 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) N-terminus DUF386 PF04074.7 KFM00830.1 - 0.13 11.7 0.0 0.36 10.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF386) RIO1 PF01163.17 KFM00831.1 - 1.1e-52 178.1 2.3 3.4e-52 176.5 1.6 1.8 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 KFM00831.1 - 1.3e-33 114.9 2.7 1.4e-33 114.8 0.2 2.2 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.18 KFM00831.1 - 1.5e-08 34.6 3.0 0.00012 21.9 0.5 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KFM00831.1 - 1.9e-07 30.3 1.6 2.1e-06 26.9 0.6 2.7 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.6 KFM00831.1 - 0.00048 19.4 0.1 0.00086 18.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) PIP49_C PF12260.3 KFM00831.1 - 0.014 14.7 0.4 0.028 13.8 0.0 1.6 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 MarR_2 PF12802.2 KFM00831.1 - 0.048 13.3 0.0 0.7 9.6 0.0 2.4 2 0 0 2 2 2 0 MarR family SH2 PF00017.19 KFM00833.1 - 8.5e-18 63.9 0.1 1.3e-17 63.3 0.1 1.3 1 0 0 1 1 1 1 SH2 domain zf-RING_2 PF13639.1 KFM00834.1 - 4.1e-10 39.3 4.0 8.8e-10 38.2 2.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KFM00834.1 - 5.1e-05 23.2 1.8 0.00014 21.8 1.3 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KFM00834.1 - 5.7e-05 22.6 3.5 0.00011 21.7 2.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM00834.1 - 0.00043 20.2 4.3 0.001 19.0 3.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM00834.1 - 0.0024 17.5 3.2 0.0056 16.3 2.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.3 KFM00834.1 - 0.2 11.6 2.9 0.43 10.5 2.0 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 KFM00834.1 - 0.76 9.8 4.6 1.4 8.9 3.2 1.5 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_3 PF13920.1 KFM00834.1 - 1.3 8.7 9.9 0.042 13.5 2.6 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFM00834.1 - 2.8 7.8 8.3 0.074 12.8 0.9 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger NeuB PF03102.9 KFM00835.1 - 2.7e-78 262.4 0.0 3.5e-78 262.0 0.0 1.1 1 0 0 1 1 1 1 NeuB family SAF PF08666.7 KFM00835.1 - 1.2e-08 35.2 0.2 2.4e-08 34.2 0.1 1.6 1 0 0 1 1 1 1 SAF domain SAF_2 PF13144.1 KFM00835.1 - 0.0031 17.0 0.0 0.0044 16.5 0.0 1.3 1 0 0 1 1 1 1 SAF-like DUF849 PF05853.7 KFM00835.1 - 0.021 13.7 0.1 0.42 9.4 0.0 2.2 1 1 1 2 2 2 0 Prokaryotic protein of unknown function (DUF849) Clathrin_lg_ch PF01086.12 KFM00836.1 - 5.2e-65 219.5 5.3 6.6e-65 219.1 3.7 1.1 1 0 0 1 1 1 1 Clathrin light chain CENP-Q PF13094.1 KFM00836.1 - 0.0002 21.4 6.4 0.00039 20.4 4.4 1.4 1 1 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Myc-LZ PF02344.10 KFM00836.1 - 0.022 14.3 3.7 0.037 13.6 2.5 1.4 1 0 0 1 1 1 0 Myc leucine zipper domain FadA PF09403.5 KFM00836.1 - 0.029 14.3 4.5 0.058 13.4 3.2 1.5 1 0 0 1 1 1 0 Adhesion protein FadA TBCA PF02970.11 KFM00836.1 - 0.14 12.2 7.5 0.41 10.7 5.2 1.8 1 0 0 1 1 1 0 Tubulin binding cofactor A APG6 PF04111.7 KFM00836.1 - 0.16 11.0 4.8 0.22 10.5 3.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 OmpH PF03938.9 KFM00836.1 - 0.17 11.8 5.3 0.26 11.2 3.7 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2265 PF10023.4 KFM00836.1 - 0.18 10.9 3.9 0.21 10.6 2.7 1.1 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) Epimerase_2 PF02350.14 KFM00837.1 - 8.3e-73 245.1 0.1 1.3e-72 244.4 0.1 1.3 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase ROK PF00480.15 KFM00837.1 - 3.5e-39 134.4 1.8 1.2e-38 132.6 0.6 2.2 2 0 0 2 2 2 1 ROK family BcrAD_BadFG PF01869.15 KFM00837.1 - 9e-05 21.8 1.9 0.23 10.6 0.2 2.5 2 1 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family Hexokinase_1 PF00349.16 KFM00837.1 - 0.0021 17.4 0.0 0.0051 16.1 0.0 1.6 1 0 0 1 1 1 1 Hexokinase DRTGG PF07085.7 KFM00837.1 - 0.0036 16.8 0.2 0.012 15.2 0.1 1.9 1 0 0 1 1 1 1 DRTGG domain FGGY_N PF00370.16 KFM00837.1 - 0.0036 16.6 0.0 0.0064 15.8 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Glucokinase PF02685.11 KFM00837.1 - 0.12 11.1 2.4 0.19 10.4 0.0 2.4 3 0 0 3 3 3 0 Glucokinase Consortin_C PF15281.1 KFM00838.1 - 4.7e-56 187.2 0.3 1.9e-55 185.3 0.0 2.2 3 0 0 3 3 3 1 Consortin C-terminus TPR_7 PF13176.1 KFM00838.1 - 0.0053 16.4 0.2 0.048 13.4 0.1 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat RrnaAD PF00398.15 KFM00839.1 - 6.1e-07 28.7 0.0 7.7e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase SET PF00856.23 KFM00841.1 - 2.4e-12 47.4 0.3 7.8e-12 45.7 0.0 1.9 2 0 0 2 2 2 1 SET domain TPR_12 PF13424.1 KFM00841.1 - 0.0067 16.3 0.0 0.044 13.7 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat Myb_DNA-bind_5 PF13873.1 KFM00841.1 - 0.069 13.0 2.4 0.2 11.5 0.3 2.2 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Blo-t-5 PF11642.3 KFM00841.1 - 0.15 11.8 1.3 0.2 11.4 0.1 1.8 2 0 0 2 2 2 0 Mite allergen Blo t 5 Kinesin PF00225.18 KFM00843.1 - 4.7e-62 209.6 0.0 7.4e-62 208.9 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain SPRY PF00622.23 KFM00844.1 - 6.2e-25 87.6 0.3 6.2e-25 87.6 0.2 2.5 3 0 0 3 3 3 1 SPRY domain AAA_33 PF13671.1 KFM00844.1 - 7e-23 81.0 0.1 1.5e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KFM00844.1 - 4.6e-05 22.6 0.2 8.8e-05 21.6 0.0 1.5 2 0 0 2 2 2 1 Zeta toxin AAA_17 PF13207.1 KFM00844.1 - 0.013 16.3 0.0 0.047 14.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 KFM00844.1 - 0.018 14.4 0.3 0.031 13.7 0.2 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF3767 PF12597.3 KFM00845.1 - 3.5e-15 55.6 0.1 4.4e-15 55.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) Vitelline_membr PF10542.4 KFM00845.1 - 0.037 13.6 0.0 1 9.0 0.0 2.1 2 0 0 2 2 2 0 Vitelline membrane cysteine-rich region Peptidase_C97 PF05903.9 KFM00846.1 - 5.6e-39 133.3 0.0 7.3e-39 132.9 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain YxiJ PF14176.1 KFM00846.1 - 0.054 13.6 0.0 0.088 12.9 0.0 1.3 1 0 0 1 1 1 0 YxiJ-like protein RNase_H2-Ydr279 PF09468.5 KFM00846.1 - 0.063 12.4 0.0 0.075 12.2 0.0 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) LRAT PF04970.8 KFM00846.1 - 0.088 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Adenylsucc_synt PF00709.16 KFM00847.1 - 5.2e-145 483.2 0.0 5.9e-145 483.1 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Spore_YpjB PF09577.5 KFM00847.1 - 0.032 13.7 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) BTB PF00651.26 KFM00848.1 - 2.9e-27 94.8 1.2 5.2e-27 94.0 0.8 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 KFM00848.1 - 8.2e-18 63.7 23.0 3.6e-08 33.2 1.4 5.7 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 KFM00848.1 - 5.5e-13 48.4 35.0 0.0015 18.7 1.6 5.2 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM00848.1 - 5.3e-12 45.1 29.4 0.0053 16.9 1.9 4.9 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM00848.1 - 0.00013 22.0 17.2 0.011 15.9 0.0 5.0 4 1 1 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM00848.1 - 0.0016 18.5 0.1 0.0016 18.5 0.1 5.1 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFM00848.1 - 0.011 15.6 22.8 0.099 12.5 0.8 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger GAGA PF09237.6 KFM00848.1 - 0.018 14.5 6.3 0.45 10.1 0.2 3.5 2 1 1 3 3 3 0 GAGA factor zinc_ribbon_5 PF13719.1 KFM00848.1 - 0.23 11.0 3.5 44 3.7 0.0 3.8 3 0 0 3 3 3 0 zinc-ribbon domain CpXC PF14353.1 KFM00848.1 - 0.62 10.0 6.6 2.6 8.0 0.5 2.8 2 0 0 2 2 2 0 CpXC protein zinc_ribbon_4 PF13717.1 KFM00848.1 - 0.9 9.2 5.0 36 4.1 0.0 3.8 3 0 0 3 3 3 0 zinc-ribbon domain RRN7 PF11781.3 KFM00848.1 - 3.3 7.3 6.3 5.5 6.5 0.1 2.9 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 Pkinase PF00069.20 KFM00849.1 - 9.6e-76 254.3 0.1 3.1e-75 252.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM00849.1 - 1.2e-36 126.1 0.0 1.6e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM00849.1 - 5.3e-08 32.1 0.0 1.3e-07 30.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like PH PF00169.24 KFM00849.1 - 6.7e-08 32.6 0.2 2.8e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 PH domain Pkinase_C PF00433.19 KFM00849.1 - 3.7e-07 30.5 2.3 7.2e-07 29.6 1.6 1.4 1 0 0 1 1 1 1 Protein kinase C terminal domain PH_11 PF15413.1 KFM00849.1 - 0.14 12.4 1.0 3.2 8.0 0.7 2.7 1 1 0 1 1 1 0 Pleckstrin homology domain Cast PF10174.4 KFM00850.1 - 0.00052 18.2 0.1 0.00052 18.2 0.1 4.5 3 1 1 4 4 4 2 RIM-binding protein of the cytomatrix active zone CENP-F_leu_zip PF10473.4 KFM00850.1 - 0.013 15.3 14.1 0.013 15.3 9.8 7.4 2 1 5 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc24 PF08286.6 KFM00850.1 - 0.03 14.0 0.3 0.03 14.0 0.2 8.5 3 1 4 7 7 7 0 Spc24 subunit of Ndc80 Reo_sigmaC PF04582.7 KFM00850.1 - 0.1 11.7 27.1 0.98 8.5 1.4 4.9 2 1 2 5 5 5 0 Reovirus sigma C capsid protein CEP170_C PF15308.1 KFM00851.1 - 2.2e-250 832.7 62.3 2.2e-250 832.7 43.2 3.9 4 0 0 4 4 4 1 CEP170 C-terminus FHA PF00498.21 KFM00851.1 - 1.4e-14 53.9 0.1 6.7e-14 51.7 0.0 2.3 2 0 0 2 2 2 1 FHA domain Gyro_capsid PF04162.7 KFM00852.1 - 0.074 11.2 0.1 0.074 11.2 0.1 1.0 1 0 0 1 1 1 0 Gyrovirus capsid protein (VP1) RVT_1 PF00078.22 KFM00853.1 - 0.068 12.5 0.1 0.12 11.6 0.0 1.4 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) PLDc_3 PF13918.1 KFM00854.1 - 2.4e-67 225.7 0.2 2.4e-67 225.7 0.2 1.7 3 0 0 3 3 3 1 PLD-like domain PLDc_2 PF13091.1 KFM00854.1 - 1.3e-12 47.5 0.1 5.9e-07 29.2 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KFM00854.1 - 1.1e-07 31.4 1.4 8.9e-05 22.1 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif DUF1669 PF07894.7 KFM00854.1 - 0.022 13.9 0.0 0.047 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1669) Atg8 PF02991.11 KFM00856.1 - 1.2e-31 108.7 0.8 1.4e-31 108.5 0.6 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 KFM00856.1 - 2.9e-06 27.3 0.1 3.3e-06 27.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 XPG_I PF00867.13 KFM00857.1 - 2.1e-26 91.8 0.1 8e-26 89.9 0.1 2.1 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KFM00857.1 - 4.8e-23 81.3 0.0 1e-22 80.2 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 KFM00857.1 - 0.00049 19.6 1.6 0.00052 19.5 0.0 1.8 2 0 0 2 2 2 1 XPG domain containing WD40 PF00400.27 KFM00858.1 - 2.2e-07 30.4 0.2 0.0068 16.2 0.0 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KFM00858.1 - 0.018 13.8 0.0 1.2 7.7 0.0 2.0 1 1 1 2 2 2 0 Nup133 N terminal like WD40 PF00400.27 KFM00859.1 - 0.03 14.1 4.0 0.85 9.6 0.6 2.8 2 0 0 2 2 2 0 WD domain, G-beta repeat 7tm_1 PF00001.16 KFM00860.1 - 5.7e-26 91.2 15.3 6.5e-26 91.0 10.6 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Herpes_UL49_5 PF05702.6 KFM00860.1 - 0.0078 16.0 1.4 0.47 10.3 0.1 2.6 2 0 0 2 2 2 2 Herpesvirus UL49.5 envelope/tegument protein Pex24p PF06398.6 KFM00860.1 - 2.9 6.5 7.8 2.8 6.6 0.2 2.2 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin Mannosyl_trans PF05007.8 KFM00861.1 - 2.8e-97 325.4 21.2 3.7e-97 325.0 14.7 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 KFM00861.1 - 2.8e-19 69.2 12.3 2.8e-19 69.2 8.5 1.7 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 KFM00861.1 - 2.5e-07 30.4 15.0 2.5e-07 30.4 10.4 3.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2029) RGS PF00615.14 KFM00862.1 - 6.6e-35 119.7 0.5 3.4e-34 117.4 0.0 2.4 3 0 0 3 3 3 1 Regulator of G protein signaling domain DEP PF00610.16 KFM00862.1 - 6.5e-17 61.0 0.0 3.3e-16 58.7 0.0 2.2 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) G-gamma PF00631.17 KFM00862.1 - 2.9e-15 55.7 0.1 9.5e-15 54.1 0.0 1.9 1 0 0 1 1 1 1 GGL domain DAN PF03045.10 KFM00864.1 - 1e-40 137.9 11.4 1.3e-40 137.6 7.9 1.1 1 0 0 1 1 1 1 DAN domain Cys_knot PF00007.17 KFM00864.1 - 6.4e-05 22.9 8.0 9.4e-05 22.4 5.5 1.2 1 0 0 1 1 1 1 Cystine-knot domain TIR_2 PF13676.1 KFM00864.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 TIR domain FH2 PF02181.18 KFM00865.1 - 0.0012 17.7 0.8 0.0016 17.3 0.1 1.5 2 0 0 2 2 2 1 Formin Homology 2 Domain CAT PF00302.13 KFM00865.1 - 0.12 11.9 0.1 0.12 11.9 0.1 1.1 1 0 0 1 1 1 0 Chloramphenicol acetyltransferase FH2 PF02181.18 KFM00866.1 - 4.8e-87 292.2 6.5 5.4e-87 292.0 4.5 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain tRNA-synt_His PF13393.1 KFM00866.1 - 0.09 11.8 1.4 0.17 10.8 1.0 1.4 1 0 0 1 1 1 0 Histidyl-tRNA synthetase Drf_FH1 PF06346.7 KFM00866.1 - 0.95 8.9 87.5 2.8 7.4 60.7 1.7 1 1 0 1 1 1 0 Formin Homology Region 1 7tm_1 PF00001.16 KFM00867.1 - 4.2e-86 288.2 11.1 9.6e-86 287.0 7.7 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM00867.1 - 7.9e-09 35.0 5.5 7.9e-09 35.0 3.8 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM00867.1 - 9.1e-07 28.2 7.1 9.1e-07 28.2 4.9 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Yae1_N PF09811.4 KFM00870.1 - 2.6e-20 71.6 64.3 1.5e+04 -24.9 44.6 5.7 1 1 0 1 1 1 0 Essential protein Yae1, N terminal zf-DHHC PF01529.15 KFM00873.1 - 8.7e-42 142.4 8.5 1.1e-41 142.0 5.9 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF4131 PF13567.1 KFM00873.1 - 0.089 12.1 2.2 0.14 11.5 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Calc_CGRP_IAPP PF00214.14 KFM00873.1 - 0.18 11.8 0.3 0.39 10.7 0.0 1.6 2 0 0 2 2 2 0 Calcitonin / CGRP / IAPP family DUF1600 PF07667.6 KFM00873.1 - 0.21 11.6 7.5 0.35 10.9 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1600) Spt4 PF06093.8 KFM00873.1 - 2.4 8.0 6.8 4.1 7.3 4.7 1.3 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger FGF PF00167.13 KFM00874.1 - 5.5e-32 110.0 0.1 6.3e-32 109.9 0.0 1.0 1 0 0 1 1 1 1 Fibroblast growth factor SIR2 PF02146.12 KFM00874.1 - 0.1 12.2 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Sir2 family SNF2_N PF00176.18 KFM00875.1 - 2.7e-63 213.5 0.0 2.7e-63 213.5 0.0 2.4 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFM00875.1 - 1.1e-14 54.0 0.0 5.1e-14 51.8 0.0 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OST3_OST6 PF04756.8 KFM00876.1 - 9.1e-51 171.5 0.0 1.4e-50 170.9 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 KFM00876.1 - 0.00067 19.3 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DUF4131 PF13567.1 KFM00876.1 - 0.046 13.1 3.3 0.084 12.2 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) COX7B PF05392.6 KFM00877.1 - 8.2e-30 102.2 0.0 8.7e-30 102.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C oxidase chain VIIB HMA PF00403.21 KFM00878.1 - 2.7e-79 261.2 14.5 2.4e-12 46.8 0.0 7.7 7 0 0 7 7 7 7 Heavy-metal-associated domain Hydrolase PF00702.21 KFM00878.1 - 1.7e-72 244.3 0.7 4.1e-72 243.0 0.5 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KFM00878.1 - 4.3e-49 166.6 2.4 4.3e-49 166.6 1.7 2.0 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 KFM00878.1 - 3.7e-13 50.0 0.1 2.1e-12 47.6 0.1 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFM00878.1 - 2.2e-05 24.1 1.5 0.0042 16.6 0.6 2.9 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 KFM00878.1 - 0.011 15.6 0.1 0.073 12.9 0.0 2.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF1980 PF09323.5 KFM00878.1 - 0.015 15.0 0.1 0.061 13.0 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF2997 PF11211.3 KFM00878.1 - 9.4 5.7 11.3 3.1 7.2 0.1 4.2 5 0 0 5 5 5 0 Protein of unknown function (DUF2997) PGK PF00162.14 KFM00879.1 - 2.8e-146 487.0 0.2 3.1e-146 486.8 0.1 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Angiomotin_C PF12240.3 KFM00880.1 - 8.2e-94 312.8 20.4 8.2e-94 312.8 14.1 3.0 2 1 0 2 2 2 1 Angiomotin C terminal NPV_P10 PF05531.7 KFM00880.1 - 1.4 9.2 7.1 9.9 6.4 1.2 3.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Ion_trans PF00520.26 KFM00881.1 - 7.1e-33 113.5 11.8 1.1e-32 112.8 8.2 1.3 1 0 0 1 1 1 1 Ion transport protein TRP_2 PF08344.6 KFM00881.1 - 2e-30 104.4 1.0 4.5e-30 103.3 0.7 1.7 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_2 PF12796.2 KFM00881.1 - 1.1e-12 48.0 0.7 3e-07 30.6 0.3 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFM00881.1 - 7.9e-10 38.9 0.1 0.00047 20.5 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 KFM00881.1 - 1.5e-08 33.9 1.4 0.00086 18.9 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KFM00881.1 - 1.6e-06 28.1 0.0 0.19 12.0 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM00881.1 - 5.8e-06 26.0 5.0 0.058 13.6 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat PKD_channel PF08016.7 KFM00881.1 - 0.00094 17.7 15.9 0.091 11.1 2.7 2.8 2 1 0 2 2 2 2 Polycystin cation channel Glyco_tran_28_C PF04101.11 KFM00882.1 - 7.9e-22 77.6 0.0 8.4e-22 77.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 KFM00882.1 - 2.2e-05 23.8 0.0 2.4e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 1 DCX PF03607.12 KFM00884.1 - 9.3e-47 156.4 0.2 7.2e-24 83.1 0.0 2.3 2 0 0 2 2 2 2 Doublecortin Peptidase_C2 PF00648.16 KFM00885.1 - 3.9e-108 360.9 0.8 6.7e-108 360.1 0.6 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 KFM00885.1 - 8e-37 126.1 0.1 1.3e-36 125.4 0.1 1.3 1 0 0 1 1 1 1 Calpain large subunit, domain III C2 PF00168.25 KFM00885.1 - 3.5e-13 49.2 0.0 7e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 C2 domain Pkinase PF00069.20 KFM00886.1 - 1.7e-72 243.6 0.0 3.1e-72 242.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM00886.1 - 1.8e-45 155.0 0.0 2.8e-45 154.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 KFM00886.1 - 1.2e-22 80.0 0.0 3.3e-22 78.6 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 KFM00886.1 - 2.8e-08 33.0 0.0 8.8e-05 21.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KFM00886.1 - 0.0011 18.7 0.0 0.012 15.3 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family DSHCT PF08148.7 KFM00886.1 - 0.0032 16.7 0.0 0.0073 15.5 0.0 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain Kdo PF06293.9 KFM00886.1 - 0.14 11.2 0.0 0.3 10.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family VWC PF00093.13 KFM00887.1 - 3.3e-27 94.3 59.1 8.7e-10 38.5 7.1 3.8 4 0 0 4 4 4 3 von Willebrand factor type C domain DUF1496 PF07383.7 KFM00887.1 - 0.00025 20.2 0.2 0.33 10.2 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF1496) AMMECR1 PF01871.12 KFM00889.1 - 9.6e-44 148.5 0.0 1.2e-43 148.2 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 Peptidase_M14 PF00246.19 KFM00890.1 - 1.1e-84 284.3 0.1 1.4e-84 284.0 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 KFM00890.1 - 1.3e-11 43.9 0.2 3.6e-11 42.5 0.0 1.9 2 0 0 2 2 2 1 Carboxypeptidase activation peptide PDDEXK_3 PF13366.1 KFM00890.1 - 0.09 12.8 0.2 0.46 10.5 0.0 2.0 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily Sec7 PF01369.15 KFM00891.1 - 1.8e-72 243.0 0.6 6.7e-72 241.1 0.4 2.1 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 KFM00891.1 - 7.4e-56 188.1 4.6 7.4e-56 188.1 3.2 3.1 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KFM00891.1 - 2.6e-30 103.7 0.2 2.6e-30 103.7 0.2 5.3 8 0 0 8 8 8 1 Domain of unknown function (DUF1981) CCDC66 PF15236.1 KFM00892.1 - 0.00033 20.3 38.3 0.00033 20.3 26.5 7.9 6 2 1 7 7 7 3 Coiled-coil domain-containing protein 66 CAF-1_p150 PF11600.3 KFM00892.1 - 0.00061 19.2 41.4 0.00061 19.2 28.7 5.7 6 0 0 6 6 6 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal JAB PF01398.16 KFM00893.1 - 3.3e-32 110.5 0.0 5.5e-32 109.8 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 KFM00893.1 - 1.8e-06 27.4 0.0 2.8e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 KFM00893.1 - 0.0051 16.3 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) LRR_4 PF12799.2 KFM00894.1 - 5.4e-23 80.1 24.3 1.5e-07 30.8 2.9 4.9 3 2 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM00894.1 - 9.6e-15 54.0 20.1 3.8e-06 26.5 2.5 4.5 2 2 1 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 KFM00894.1 - 4e-12 44.3 23.2 0.18 11.9 0.1 7.3 7 0 0 7 7 7 5 Leucine Rich Repeat LRR_6 PF13516.1 KFM00894.1 - 4.4e-10 38.5 25.8 0.098 12.7 0.0 6.8 5 2 1 7 7 7 5 Leucine Rich repeat LRR_9 PF14580.1 KFM00894.1 - 7.9e-10 38.5 8.7 0.00011 21.8 0.3 2.5 2 1 0 2 2 2 2 Leucine-rich repeat LRR_7 PF13504.1 KFM00894.1 - 1.7e-06 27.2 17.1 0.89 10.0 0.0 7.2 7 0 0 7 7 7 3 Leucine rich repeat Tn7_Tnp_TnsA_C PF08721.6 KFM00894.1 - 0.19 11.7 2.6 2.6 8.0 0.4 2.5 2 0 0 2 2 2 0 TnsA endonuclease C terminal FNIP PF05725.7 KFM00894.1 - 1.3 9.0 6.5 6.3 6.8 2.0 3.5 2 1 0 2 2 2 0 FNIP Repeat MCM PF00493.18 KFM00895.1 - 8.2e-18 64.2 0.2 4.8e-17 61.7 0.1 1.9 1 1 0 1 1 1 1 MCM2/3/5 family Pkinase PF00069.20 KFM00896.1 - 1.9e-66 223.8 0.0 2.3e-66 223.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM00896.1 - 1.5e-34 119.2 0.0 1.8e-34 119.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM00896.1 - 3.8e-05 22.7 0.0 0.00011 21.2 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase_C PF00433.19 KFM00896.1 - 0.00022 21.6 0.1 0.00037 20.9 0.1 1.4 1 0 0 1 1 1 1 Protein kinase C terminal domain Kdo PF06293.9 KFM00896.1 - 0.0061 15.6 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFM00896.1 - 0.048 13.3 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family OTU PF02338.14 KFM00897.1 - 1.5e-25 90.0 0.0 4.4e-25 88.6 0.0 1.9 1 0 0 1 1 1 1 OTU-like cysteine protease Mut7-C PF01927.11 KFM00897.1 - 0.076 12.9 0.1 2.5 8.0 0.1 2.7 2 0 0 2 2 2 0 Mut7-C RNAse domain DUF4648 PF15505.1 KFM00898.1 - 7.7e-36 123.8 0.1 8.3e-36 123.7 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4648) Fe-ADH PF00465.14 KFM00899.1 - 8.9e-105 350.3 0.0 1.1e-104 350.0 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 KFM00899.1 - 3.3e-15 56.0 0.0 1.6e-11 43.9 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 KFM00899.1 - 0.0014 18.0 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein CRF PF00473.12 KFM00900.1 - 3e-17 62.4 1.1 3e-17 62.4 0.7 1.9 3 0 0 3 3 3 1 Corticotropin-releasing factor family UCN2 PF11613.3 KFM00900.1 - 0.013 15.3 0.1 0.02 14.8 0.1 1.2 1 0 0 1 1 1 0 Agonist of corticotropin releasing factor R2, Urocortin-2 Elongin_A PF06881.6 KFM00900.1 - 0.014 15.7 0.3 0.032 14.6 0.0 1.7 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A zf-C3HC4_2 PF13923.1 KFM00901.1 - 7.3e-10 38.7 5.3 7.3e-10 38.7 3.7 2.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFM00901.1 - 2.8e-09 36.5 4.2 9.3e-09 34.8 1.9 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.1 KFM00901.1 - 2e-08 33.9 4.8 2e-08 33.9 3.3 2.4 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.20 KFM00901.1 - 4.5e-08 32.6 3.3 4.5e-08 32.6 2.3 2.6 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM00901.1 - 5.8e-08 32.2 4.4 5.8e-08 32.2 3.1 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM00901.1 - 8.1e-07 28.6 4.8 8.1e-07 28.6 3.3 2.7 3 0 0 3 3 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFM00901.1 - 1.3e-05 24.9 7.2 1.3e-05 24.9 5.0 3.2 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 KFM00901.1 - 2.3e-05 24.0 0.4 2.3e-05 24.0 0.3 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-B_box PF00643.19 KFM00901.1 - 3.2e-05 23.7 9.5 3.2e-05 23.7 6.6 3.9 4 0 0 4 4 4 1 B-box zinc finger Flagellin_C PF00700.16 KFM00901.1 - 0.045 13.9 0.2 0.21 11.7 0.1 2.1 1 1 1 2 2 2 0 Bacterial flagellin C-terminal helical region DUF1886 PF09171.5 KFM00901.1 - 0.058 12.4 0.3 0.12 11.3 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1886) DnaJ PF00226.26 KFM00902.1 - 9.2e-16 57.3 1.2 1.6e-15 56.5 0.8 1.4 1 0 0 1 1 1 1 DnaJ domain GP41 PF00517.12 KFM00902.1 - 0.033 13.7 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 Retroviral envelope protein Corona_S2 PF01601.11 KFM00902.1 - 0.14 10.2 4.7 0.16 10.0 3.2 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Arrestin_N PF00339.24 KFM00903.1 - 2.5e-19 69.5 0.0 3.5e-14 52.8 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KFM00903.1 - 2.7e-17 63.1 0.0 4.1e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain DUF2393 PF09624.5 KFM00903.1 - 0.029 13.8 0.3 0.055 12.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) AP3B1_C PF14796.1 KFM00903.1 - 0.15 11.7 0.1 0.27 10.9 0.1 1.4 1 0 0 1 1 1 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal WD40 PF00400.27 KFM00904.1 - 1e-12 47.3 2.0 0.0056 16.5 0.0 4.0 3 0 0 3 3 3 3 WD domain, G-beta repeat Reprolysin PF01421.14 KFM00905.1 - 6.6e-41 140.0 1.5 6.6e-41 140.0 1.0 2.1 2 0 0 2 2 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.7 KFM00905.1 - 1.9e-31 108.5 8.7 1.9e-31 108.5 6.0 3.6 3 1 0 3 3 2 1 ADAM cysteine-rich Pep_M12B_propep PF01562.14 KFM00905.1 - 4e-22 78.4 0.3 7e-22 77.6 0.0 1.6 2 0 0 2 2 1 1 Reprolysin family propeptide Disintegrin PF00200.18 KFM00905.1 - 2.2e-21 75.8 26.7 2.2e-21 75.8 18.5 4.6 2 1 1 4 4 1 1 Disintegrin Reprolysin_5 PF13688.1 KFM00905.1 - 6.4e-15 55.6 1.4 1.3e-14 54.5 1.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KFM00905.1 - 5.4e-14 52.7 0.1 9.4e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFM00905.1 - 8.1e-11 42.2 1.0 1.4e-10 41.5 0.7 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFM00905.1 - 7.5e-10 38.6 0.2 1.2e-09 38.0 0.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like EGF_2 PF07974.8 KFM00905.1 - 0.00013 22.0 11.8 0.00013 22.0 8.2 7.5 5 1 1 6 6 2 1 EGF-like domain Peptidase_M10 PF00413.19 KFM00905.1 - 0.0016 18.1 0.4 0.0034 17.1 0.3 1.4 1 1 0 1 1 1 1 Matrixin Peptidase_M57 PF12388.3 KFM00905.1 - 0.0046 16.2 0.2 0.0046 16.2 0.2 2.2 2 0 0 2 2 2 1 Dual-action HEIGH metallo-peptidase Astacin PF01400.19 KFM00905.1 - 0.0053 16.1 0.1 0.011 15.1 0.1 1.5 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M43 PF05572.8 KFM00905.1 - 0.092 12.3 0.4 0.23 11.0 0.3 1.7 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A OATP PF03137.15 KFM00906.1 - 1.2e-174 581.3 12.1 1e-98 330.7 0.5 2.0 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 KFM00906.1 - 1.2e-20 73.5 33.4 5.1e-18 64.9 16.7 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily Kazal_2 PF07648.10 KFM00906.1 - 7.5e-05 22.5 4.9 7.5e-05 22.5 3.4 2.3 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 KFM00906.1 - 0.003 17.5 4.0 0.0088 16.0 2.7 1.8 1 1 0 1 1 1 1 Kazal-type serine protease inhibitor domain EMP70 PF02990.11 KFM00906.1 - 0.81 8.0 2.7 1.6 7.1 1.9 1.4 1 0 0 1 1 1 0 Endomembrane protein 70 PGM_PMM_I PF02878.11 KFM00908.1 - 2.2e-35 121.1 0.0 6.3e-35 119.6 0.0 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 KFM00908.1 - 4.9e-24 84.6 0.1 3.6e-23 81.8 0.0 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 KFM00908.1 - 8.6e-09 35.4 0.0 1.8e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 KFM00908.1 - 5.1e-08 32.8 0.0 2.8e-07 30.4 0.0 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain ISK_Channel PF02060.10 KFM00909.1 - 1.4e-06 27.9 0.0 1.8e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Slow voltage-gated potassium channel DUF1109 PF06532.6 KFM00909.1 - 0.038 13.3 0.0 0.043 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1109) CDC27 PF09507.5 KFM00911.1 - 2.6e-128 428.9 36.4 2.9e-128 428.7 25.2 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 VWC PF00093.13 KFM00912.1 - 3.1e-28 97.6 58.3 4e-11 42.8 8.4 3.3 3 0 0 3 3 3 3 von Willebrand factor type C domain DUF3601 PF12208.3 KFM00912.1 - 0.026 14.4 0.2 16 5.5 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3601) SPC25 PF06703.6 KFM00914.1 - 2.8e-51 173.3 1.6 9.7e-27 93.5 0.1 2.0 1 1 1 2 2 2 2 Microsomal signal peptidase 25 kDa subunit (SPC25) CTP_transf_1 PF01148.15 KFM00914.1 - 0.039 13.6 1.6 0.051 13.2 1.1 1.1 1 0 0 1 1 1 0 Cytidylyltransferase family Cadherin PF00028.12 KFM00915.1 - 1.9e-107 351.7 3.4 6.7e-23 80.7 0.0 7.6 7 1 1 8 8 8 7 Cadherin domain Protocadherin PF08374.6 KFM00915.1 - 1.5e-71 240.5 0.4 2.5e-71 239.8 0.2 1.4 1 0 0 1 1 1 1 Protocadherin Cadherin_2 PF08266.7 KFM00915.1 - 5.3e-14 51.5 0.1 3.7e-05 23.2 0.0 5.2 5 0 0 5 5 5 2 Cadherin-like BACON PF13004.2 KFM00915.1 - 0.0012 19.0 6.6 1.9 8.7 0.2 5.2 5 1 0 5 5 5 2 Bacteroidetes-Associated Carbohydrate-binding Often N-terminal Mid2 PF04478.7 KFM00915.1 - 0.0014 18.0 0.2 0.0032 16.8 0.1 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DUF3827 PF12877.2 KFM00915.1 - 0.0027 15.8 0.0 0.0041 15.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3827) He_PIG PF05345.7 KFM00915.1 - 0.0074 16.2 7.8 1.3 9.1 0.1 5.4 6 1 1 7 7 7 2 Putative Ig domain TMEM154 PF15102.1 KFM00915.1 - 0.0093 15.6 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 1 TMEM154 protein family Glycophorin_A PF01102.13 KFM00915.1 - 0.051 13.3 0.1 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Glycophorin A EphA2_TM PF14575.1 KFM00915.1 - 0.097 13.0 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.1 KFM00915.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Glyco_transf_54 PF04666.8 KFM00919.1 - 1.8e-133 443.9 0.9 2.3e-133 443.5 0.6 1.1 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region DUF3989 PF13150.1 KFM00919.1 - 0.014 14.8 0.2 0.41 10.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) GAS PF13851.1 KFM00919.1 - 0.032 13.4 1.4 0.058 12.5 1.0 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4592 PF15262.1 KFM00921.1 - 7.3e-30 104.1 11.3 8.4e-30 103.9 3.6 3.0 2 1 0 2 2 2 1 Domain of unknown function (DUF4592) BPL_LplA_LipB PF03099.14 KFM00922.1 - 7.5e-22 77.6 0.0 1.3e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF4121 PF13497.1 KFM00922.1 - 0.11 11.4 0.0 0.27 10.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4121) MIT PF04212.13 KFM00923.1 - 8e-06 25.6 1.0 1.8e-05 24.5 0.7 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain L_HGMIC_fpl PF10242.4 KFM00924.1 - 5.5e-05 23.2 1.8 5.5e-05 23.2 1.3 2.4 1 1 1 2 2 2 1 Lipoma HMGIC fusion partner-like protein Clc-like PF07062.7 KFM00924.1 - 0.00033 19.9 0.1 0.00033 19.9 0.1 2.1 2 1 1 3 3 3 1 Clc-like Claudin_3 PF06653.6 KFM00924.1 - 0.00062 19.5 4.5 0.18 11.5 0.0 2.4 2 0 0 2 2 2 2 Tight junction protein, Claudin-like Neurensin PF14927.1 KFM00924.1 - 0.054 12.8 0.3 0.14 11.5 0.1 1.9 1 1 0 1 1 1 0 Neurensin Claudin_2 PF13903.1 KFM00924.1 - 0.063 12.9 8.1 0.76 9.4 5.6 2.3 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Telomere_reg-2 PF10193.4 KFM00925.1 - 1.2e-35 122.2 0.2 1.2e-35 122.2 0.1 2.2 3 0 0 3 3 3 1 Telomere length regulation protein Cnd1 PF12717.2 KFM00925.1 - 0.074 12.8 0.3 7.3 6.4 0.0 3.2 2 1 2 4 4 4 0 non-SMC mitotic condensation complex subunit 1 RRM_1 PF00076.17 KFM00926.1 - 2.5e-20 71.8 0.0 3.8e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM00926.1 - 9.3e-16 57.5 0.0 1.4e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM00926.1 - 2.5e-10 40.0 0.0 3.6e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KFM00926.1 - 0.00061 19.4 0.0 0.0022 17.7 0.0 1.9 1 0 0 1 1 1 1 Limkain b1 RRM_3 PF08777.6 KFM00926.1 - 0.00063 19.5 0.0 0.002 17.9 0.0 1.8 1 1 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.1 KFM00926.1 - 0.0012 18.5 0.0 0.0021 17.7 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF605 PF04652.11 KFM00926.1 - 0.015 14.6 22.8 0.017 14.5 15.8 1.1 1 0 0 1 1 1 0 Vta1 like SOBP PF15279.1 KFM00926.1 - 0.026 14.9 17.0 0.036 14.4 11.8 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Macoilin PF09726.4 KFM00926.1 - 0.16 10.2 28.9 0.2 9.9 20.1 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF936 PF06075.7 KFM00926.1 - 2.9 6.6 38.6 3.6 6.4 26.8 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) SAPS PF04499.10 KFM00926.1 - 4.3 5.8 7.9 6.5 5.2 5.4 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein LTD PF00932.14 KFM00927.1 - 0.00029 20.9 0.0 0.0006 19.8 0.0 1.6 1 0 0 1 1 1 1 Lamin Tail Domain Nepo_coat PF03391.10 KFM00927.1 - 0.11 11.7 0.1 0.23 10.7 0.1 1.5 1 0 0 1 1 1 0 Nepovirus coat protein, central domain PX PF00787.19 KFM00928.1 - 0.027 14.2 0.1 0.047 13.4 0.1 1.4 1 0 0 1 1 1 0 PX domain DUF3538 PF12057.3 KFM00928.1 - 0.054 13.0 0.1 0.072 12.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3538) EssA PF10661.4 KFM00928.1 - 0.058 13.0 0.2 0.072 12.7 0.2 1.2 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA Con-6 PF10346.4 KFM00928.1 - 5 6.6 7.0 0.91 8.9 0.0 3.0 3 1 0 3 3 3 0 Conidiation protein 6 DUF4615 PF15393.1 KFM00929.1 - 1.1e-42 145.1 3.2 1.1e-42 145.1 2.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4615) CRT10 PF08728.5 KFM00929.1 - 1.3 6.9 6.0 1.4 6.7 4.2 1.2 1 0 0 1 1 1 0 CRT10 Ycf1 PF05758.7 KFM00929.1 - 5 4.7 13.3 6.1 4.4 9.2 1.0 1 0 0 1 1 1 0 Ycf1 ATP-synt_C PF00137.16 KFM00930.1 - 4.9e-31 106.4 29.2 5.1e-19 67.9 8.2 2.0 2 0 0 2 2 2 2 ATP synthase subunit C TLD PF07534.11 KFM00931.1 - 7e-29 100.6 0.2 5.7e-27 94.3 0.1 2.3 1 1 0 1 1 1 1 TLD RabGAP-TBC PF00566.13 KFM00931.1 - 6.2e-22 78.1 0.1 8.8e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Laminin_N PF00055.12 KFM00932.1 - 1.9e-49 167.7 3.4 2.3e-48 164.2 0.0 2.8 2 1 0 2 2 2 1 Laminin N-terminal (Domain VI) NTR PF01759.16 KFM00932.1 - 9.5e-29 99.2 1.9 3e-28 97.5 1.3 1.9 1 0 0 1 1 1 1 UNC-6/NTR/C345C module Laminin_EGF PF00053.19 KFM00932.1 - 1.4e-25 88.9 68.8 7.2e-11 41.8 9.9 4.9 4 1 1 5 5 5 3 Laminin EGF-like (Domains III and V) Tmemb_cc2 PF10267.4 KFM00933.1 - 0.0031 16.1 1.4 0.0031 16.1 1.0 1.5 1 1 1 2 2 2 1 Predicted transmembrane and coiled-coil 2 protein Retrotrans_gag PF03732.12 KFM00933.1 - 0.021 14.8 1.8 0.04 13.9 1.0 1.6 1 1 0 1 1 1 0 Retrotransposon gag protein DUF1221 PF06760.6 KFM00933.1 - 0.054 12.7 0.1 0.07 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) fn3 PF00041.16 KFM00934.1 - 8.2e-12 45.0 0.4 1.5e-11 44.2 0.3 1.5 1 0 0 1 1 1 1 Fibronectin type III domain Ank_4 PF13637.1 KFM00934.1 - 0.00016 22.1 0.0 0.00031 21.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KFM00934.1 - 0.00058 20.1 0.0 0.0013 19.0 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFM00934.1 - 0.0061 16.7 0.0 0.024 14.8 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 KFM00934.1 - 0.073 12.9 0.1 0.36 10.7 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeat Big_5 PF13205.1 KFM00934.1 - 0.076 13.6 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial Ig-like domain Cyclin_N PF00134.18 KFM00936.1 - 6.7e-27 93.5 2.9 1.1e-25 89.6 0.2 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFM00936.1 - 6.4e-17 61.5 0.5 1.6e-16 60.3 0.3 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain F-box PF00646.28 KFM00936.1 - 1.5e-05 24.5 0.1 4.6e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KFM00936.1 - 9.1e-05 22.1 0.9 0.00023 20.8 0.1 2.2 2 0 0 2 2 2 1 F-box-like Pkinase PF00069.20 KFM00937.1 - 4e-11 42.5 0.0 4.7e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM00937.1 - 1.8e-06 27.2 0.0 2.4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ABC2_membrane_3 PF12698.2 KFM00938.1 - 1.6e-62 211.5 36.4 2.2e-33 115.7 15.5 2.2 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.22 KFM00938.1 - 2.3e-48 163.9 0.0 3.1e-23 82.5 0.0 2.7 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KFM00938.1 - 2e-17 64.1 0.1 5.7e-05 23.2 0.0 4.3 3 1 0 4 4 4 3 AAA domain AAA_23 PF13476.1 KFM00938.1 - 6.1e-05 23.4 2.3 0.0055 17.0 0.0 2.8 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.1 KFM00938.1 - 8.6e-05 22.3 0.0 0.0064 16.3 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 KFM00938.1 - 0.00099 18.3 1.0 0.013 14.6 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_15 PF13175.1 KFM00938.1 - 0.0019 17.3 0.0 0.42 9.6 0.0 3.2 4 0 0 4 4 4 1 AAA ATPase domain AAA_29 PF13555.1 KFM00938.1 - 0.0026 17.2 3.2 0.061 12.8 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.1 KFM00938.1 - 0.026 14.1 0.8 1.1 8.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain Arf PF00025.16 KFM00938.1 - 0.072 12.3 0.7 11 5.2 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_22 PF13401.1 KFM00938.1 - 0.082 13.0 0.6 5.8 7.0 0.1 2.8 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 KFM00938.1 - 0.11 11.6 0.1 10 5.2 0.0 3.1 3 1 0 4 4 4 0 RecF/RecN/SMC N terminal domain SRP54 PF00448.17 KFM00938.1 - 0.12 11.7 5.4 0.85 9.0 0.4 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_33 PF13671.1 KFM00938.1 - 0.14 12.0 0.1 13 5.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 KFM00938.1 - 0.17 11.5 1.9 2.6 7.6 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_13 PF13166.1 KFM00938.1 - 0.21 10.0 0.2 2.2 6.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 KFM00938.1 - 0.65 9.4 2.1 12 5.2 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RELT PF12606.3 KFM00938.1 - 1.7 7.8 4.3 4.9 6.3 3.0 1.8 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 FAM195 PF14799.1 KFM00939.1 - 2.4e-31 107.5 0.2 2.7e-31 107.3 0.1 1.0 1 0 0 1 1 1 1 FAM195 family LAP2alpha PF11560.3 KFM00939.1 - 0.078 12.1 0.0 0.089 11.9 0.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 2 alpha DUF938 PF06080.7 KFM00940.1 - 3.1e-25 88.9 0.0 3.4e-25 88.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_12 PF08242.7 KFM00940.1 - 0.04 14.4 0.0 0.049 14.1 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Ras PF00071.17 KFM00941.1 - 8.3e-34 116.3 0.0 1.1e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Ras family SOCS_box PF07525.11 KFM00941.1 - 9.4e-11 41.3 0.4 2e-10 40.3 0.3 1.6 1 0 0 1 1 1 1 SOCS box Miro PF08477.8 KFM00941.1 - 2.7e-09 37.5 0.0 4.4e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM00941.1 - 0.0079 15.4 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gpi1 PF05024.10 KFM00942.1 - 2.8e-75 252.1 9.8 2.8e-75 252.1 6.8 1.9 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) Peptidase_C2 PF00648.16 KFM00943.1 - 1.1e-84 283.9 0.0 1.5e-84 283.5 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease zf-RanBP PF00641.13 KFM00943.1 - 2e-26 90.7 65.5 5.6e-08 31.7 1.3 7.3 7 0 0 7 7 7 6 Zn-finger in Ran binding protein and others DZR PF12773.2 KFM00943.1 - 2.9e-05 23.7 56.9 0.0054 16.5 5.9 6.5 4 1 2 6 6 6 4 Double zinc ribbon Methyltransf_16 PF10294.4 KFM00946.1 - 1.1e-18 67.2 0.0 4.6e-09 35.9 0.0 2.1 1 1 1 2 2 2 2 Putative methyltransferase Methyltransf_12 PF08242.7 KFM00946.1 - 0.015 15.7 0.0 0.041 14.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KFM00946.1 - 0.031 13.6 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.2 KFM00946.1 - 0.096 13.2 0.0 0.15 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 KFM00946.1 - 0.1 12.6 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Porphobil_deamC PF03900.10 KFM00946.1 - 0.11 12.6 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Porphobilinogen deaminase, C-terminal domain Methyltransf_31 PF13847.1 KFM00946.1 - 0.12 11.9 0.0 0.35 10.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 KFM00946.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Glyco_trans_1_4 PF13692.1 KFM00947.1 - 4.6e-20 72.1 0.0 9.1e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 KFM00947.1 - 1.4e-10 40.9 0.0 2.1e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KFM00947.1 - 0.00053 20.1 0.0 0.00086 19.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 KFM00947.1 - 0.014 15.6 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 DUF1472 PF07339.7 KFM00947.1 - 0.1 12.9 0.0 3.1 8.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1472) DUF2233 PF09992.4 KFM00948.1 - 9.9e-37 126.5 0.1 1.3e-36 126.2 0.1 1.1 1 0 0 1 1 1 1 Predicted periplasmic protein (DUF2233) EGF_2 PF07974.8 KFM00948.1 - 0.0011 19.1 12.5 0.0011 19.1 8.7 4.6 4 0 0 4 4 4 3 EGF-like domain hEGF PF12661.2 KFM00948.1 - 0.019 15.0 20.7 0.057 13.5 1.5 4.2 3 0 0 3 3 3 0 Human growth factor-like EGF PRELI PF04707.9 KFM00949.1 - 1.2e-44 151.6 0.4 1.8e-44 151.0 0.3 1.3 1 0 0 1 1 1 1 PRELI-like family CRAL_TRIO PF00650.15 KFM00949.1 - 1.9e-42 144.4 0.0 4.7e-42 143.1 0.0 1.7 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KFM00949.1 - 4.8e-10 39.4 0.2 1.2e-09 38.1 0.2 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KFM00949.1 - 0.021 14.7 0.0 0.08 12.8 0.0 1.9 1 1 0 1 1 1 0 Divergent CRAL/TRIO domain PDZ PF00595.19 KFM00950.1 - 1.9e-11 43.9 0.0 5e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) DUF812 PF05667.6 KFM00950.1 - 0.0011 17.5 10.3 0.0033 16.0 7.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF812) Laminin_II PF06009.7 KFM00950.1 - 0.0049 16.6 10.0 0.0096 15.6 6.9 1.5 1 0 0 1 1 1 1 Laminin Domain II CCDC74_C PF14917.1 KFM00950.1 - 0.18 11.8 9.9 0.49 10.4 6.8 1.7 1 1 0 1 1 1 0 Coiled coil protein 74, C terminal APG6 PF04111.7 KFM00950.1 - 0.31 10.0 17.5 0.55 9.2 12.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1192 PF06698.6 KFM00950.1 - 0.39 10.5 4.6 4.5 7.1 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TPR_MLP1_2 PF07926.7 KFM00950.1 - 0.79 9.4 21.3 0.096 12.4 6.2 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein FUSC PF04632.7 KFM00950.1 - 3.6 5.8 7.7 4.8 5.5 5.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family FlaC_arch PF05377.6 KFM00950.1 - 8.3 6.3 7.5 11 5.9 1.3 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4200 PF13863.1 KFM00950.1 - 9 6.2 22.7 2.1 8.3 9.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) NDK PF00334.14 KFM00951.1 - 2.5e-53 179.4 0.0 2.8e-53 179.3 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.13 KFM00951.1 - 0.0056 16.4 0.0 0.0096 15.6 0.0 1.3 1 0 0 1 1 1 1 Photosystem I reaction centre subunit IX / PsaJ ERCC4 PF02732.10 KFM00952.1 - 2.7e-06 27.1 0.0 4.3e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain Catalase-rel PF06628.7 KFM00952.1 - 0.14 12.0 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Catalase-related immune-responsive SPRY PF00622.23 KFM00953.1 - 8.4e-17 61.4 0.2 2.7e-16 59.7 0.1 1.9 2 0 0 2 2 2 1 SPRY domain SOCS_box PF07525.11 KFM00953.1 - 0.0023 17.7 2.5 0.0054 16.5 1.7 1.6 1 0 0 1 1 1 1 SOCS box ParA PF10609.4 KFM00954.1 - 1.4e-34 117.8 0.0 2.4e-34 117.0 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KFM00954.1 - 3.2e-16 59.3 0.0 5e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 KFM00954.1 - 1.9e-08 33.7 0.0 5.7e-08 32.1 0.0 1.7 1 1 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.1 KFM00954.1 - 2.2e-07 30.9 0.0 1.1e-06 28.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 KFM00954.1 - 3.2e-07 29.7 0.5 3.7e-06 26.2 0.0 2.5 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_26 PF13500.1 KFM00954.1 - 3.4e-07 30.0 0.0 1.3e-06 28.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain ArgK PF03308.11 KFM00954.1 - 5e-05 22.2 0.1 7.6e-05 21.6 0.1 1.2 1 0 0 1 1 1 1 ArgK protein Fer4_NifH PF00142.13 KFM00954.1 - 0.0002 20.6 0.0 0.0091 15.2 0.0 2.2 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family APS_kinase PF01583.15 KFM00954.1 - 0.0065 16.1 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase YhjQ PF06564.7 KFM00954.1 - 0.0071 15.7 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 YhjQ protein KTI12 PF08433.5 KFM00954.1 - 0.016 14.3 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 SRP54 PF00448.17 KFM00954.1 - 0.018 14.4 0.0 0.082 12.3 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_17 PF13207.1 KFM00954.1 - 0.03 15.1 0.2 0.12 13.1 0.3 1.9 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KFM00954.1 - 0.039 13.3 0.3 0.077 12.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KFM00954.1 - 0.072 13.4 0.6 0.095 13.0 0.4 1.4 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 KFM00954.1 - 0.086 12.5 0.0 0.17 11.6 0.0 1.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 KFM00954.1 - 0.088 11.9 0.1 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NTPase_1 PF03266.10 KFM00954.1 - 0.15 11.7 0.2 0.33 10.6 0.1 1.6 1 0 0 1 1 1 0 NTPase GFO_IDH_MocA PF01408.17 KFM00954.1 - 0.16 12.4 0.0 0.26 11.8 0.0 1.5 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Filament PF00038.16 KFM00955.1 - 0.0057 16.1 27.4 0.11 11.9 6.8 3.1 2 1 1 3 3 3 2 Intermediate filament protein Tropomyosin PF00261.15 KFM00955.1 - 0.006 15.6 7.7 0.006 15.6 5.3 2.9 3 1 0 3 3 3 1 Tropomyosin TPR_MLP1_2 PF07926.7 KFM00955.1 - 0.014 15.0 25.5 0.12 12.1 2.7 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein PyocinActivator PF11112.3 KFM00955.1 - 0.049 13.4 0.1 0.17 11.7 0.0 2.0 2 0 0 2 2 2 0 Pyocin activator protein PrtN Hemerythrin PF01814.18 KFM00955.1 - 0.32 11.1 9.8 0.26 11.4 0.6 3.5 3 1 1 4 4 4 0 Hemerythrin HHE cation binding domain CENP-F_leu_zip PF10473.4 KFM00955.1 - 1.1 9.1 28.0 0.96 9.3 6.9 3.4 3 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.7 KFM00955.1 - 1.3 8.8 15.6 1.4 8.7 4.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) SPX PF03105.14 KFM00955.1 - 1.4 8.6 15.1 5.2 6.7 4.2 2.5 1 1 1 2 2 2 0 SPX domain tRNA_bind_2 PF13725.1 KFM00955.1 - 1.8 8.7 7.5 10 6.2 2.6 3.3 2 1 0 2 2 2 0 Possible tRNA binding domain DUF2935 PF11155.3 KFM00955.1 - 2.7 8.0 7.1 4.8 7.2 0.9 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) IncA PF04156.9 KFM00955.1 - 4.3 6.8 32.2 0.23 11.0 9.3 3.1 2 2 0 2 2 2 0 IncA protein DUF2408 PF10303.4 KFM00955.1 - 7.6 6.6 13.7 1.1 9.3 0.3 3.2 2 2 0 2 2 2 0 Protein of unknown function (DUF2408) GAS PF13851.1 KFM00955.1 - 7.9 5.6 30.9 2.6 7.2 6.0 3.8 2 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding Methyltransf_26 PF13659.1 KFM00956.1 - 0.12 12.4 0.0 0.16 12.0 0.0 1.2 1 1 0 1 1 1 0 Methyltransferase domain LRR_6 PF13516.1 KFM00957.1 - 4.4e-14 50.9 5.9 0.1 12.7 0.0 8.3 8 2 1 9 9 9 4 Leucine Rich repeat LRR_4 PF12799.2 KFM00957.1 - 2.2e-11 43.1 4.7 0.14 11.7 0.0 5.3 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM00957.1 - 3.9e-09 36.1 5.4 0.0012 18.5 0.2 4.3 3 1 1 4 4 4 2 Leucine rich repeat LRR_7 PF13504.1 KFM00957.1 - 1.7e-06 27.2 9.9 2.2 8.8 0.0 7.4 8 0 0 8 8 8 2 Leucine rich repeat LRR_1 PF00560.28 KFM00957.1 - 9e-06 25.0 11.3 1.4 9.1 0.0 7.4 6 2 1 7 7 7 2 Leucine Rich Repeat F-box PF00646.28 KFM00957.1 - 0.0015 18.1 2.7 0.0047 16.5 0.1 2.5 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KFM00957.1 - 0.0046 16.6 1.2 0.015 15.0 0.8 1.9 1 0 0 1 1 1 1 F-box-like Lamprin PF06403.6 KFM00958.1 - 0.039 13.7 0.6 0.039 13.7 0.4 1.1 1 0 0 1 1 1 0 Lamprin WD40 PF00400.27 KFM00959.1 - 4e-28 96.2 5.8 4.2e-11 42.2 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat XPA_C PF05181.7 KFM00959.1 - 0.13 11.8 0.1 0.31 10.6 0.0 1.6 1 0 0 1 1 1 0 XPA protein C-terminus U-box PF04564.10 KFM00960.1 - 2.9e-31 107.2 0.0 4.7e-31 106.5 0.0 1.3 1 0 0 1 1 1 1 U-box domain TPR_1 PF00515.23 KFM00960.1 - 2.4e-16 58.5 7.0 5.3e-10 38.4 0.6 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFM00960.1 - 4.2e-14 51.9 3.8 9.5e-14 50.8 2.6 1.6 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 KFM00960.1 - 1.6e-12 46.2 6.1 8.1e-06 25.3 0.4 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFM00960.1 - 5.3e-12 45.5 2.6 1.3e-11 44.2 1.8 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 KFM00960.1 - 8e-11 41.9 2.1 1.9e-10 40.7 1.5 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 KFM00960.1 - 1.1e-09 37.3 3.8 0.00027 20.4 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFM00960.1 - 1.2e-07 32.1 0.7 2.7e-07 31.0 0.5 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFM00960.1 - 2.2e-07 31.0 2.5 4.6e-07 30.0 1.7 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFM00960.1 - 7.1e-07 28.9 0.6 0.014 15.5 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 KFM00960.1 - 1.8e-05 24.4 1.2 5e-05 23.0 0.8 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFM00960.1 - 5e-05 23.5 0.7 0.0076 16.7 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFM00960.1 - 0.00014 21.4 3.1 0.084 12.7 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFM00960.1 - 0.00068 19.9 2.6 1 9.9 0.2 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 KFM00960.1 - 0.0099 15.0 2.0 0.06 12.6 0.1 2.4 2 0 0 2 2 2 1 SHNi-TPR Rsc14 PF08586.5 KFM00960.1 - 0.043 14.2 1.9 5.1 7.6 0.0 3.1 1 1 2 3 3 3 0 RSC complex, Rsc14/Ldb7 subunit HTH_40 PF14493.1 KFM00960.1 - 0.15 12.2 2.2 0.33 11.1 1.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain TPR_10 PF13374.1 KFM00960.1 - 0.17 11.8 1.7 5.7 7.0 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.1 KFM00960.1 - 1.4 9.0 8.0 7.5 6.7 0.9 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat EF_assoc_2 PF08356.7 KFM00961.1 - 2.4e-35 120.1 0.0 6.7e-35 118.7 0.0 1.8 2 0 0 2 2 1 1 EF hand associated Miro PF08477.8 KFM00961.1 - 3e-33 114.8 0.0 2.9e-16 60.0 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein EF_assoc_1 PF08355.7 KFM00961.1 - 1.9e-27 94.3 0.6 7.4e-27 92.4 0.0 2.1 2 0 0 2 2 2 1 EF hand associated Ras PF00071.17 KFM00961.1 - 3.3e-22 78.5 0.0 1.4e-15 57.0 0.0 2.3 2 0 0 2 2 2 2 Ras family EF-hand_6 PF13405.1 KFM00961.1 - 1.5e-06 27.5 0.1 0.00021 20.9 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 KFM00961.1 - 1.5e-06 28.1 0.3 0.0019 18.2 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KFM00961.1 - 4.4e-06 25.5 0.5 0.0021 17.2 0.0 2.5 2 0 0 2 2 2 2 EF hand MMR_HSR1 PF01926.18 KFM00961.1 - 0.00017 21.5 0.0 0.072 13.0 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase EF-hand_8 PF13833.1 KFM00961.1 - 0.0006 19.3 0.1 1 9.0 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair Dynamin_N PF00350.18 KFM00961.1 - 0.0006 19.6 0.1 0.73 9.6 0.0 2.4 2 0 0 2 2 2 2 Dynamin family EF-hand_5 PF13202.1 KFM00961.1 - 0.0047 16.2 0.1 0.0096 15.2 0.0 1.6 1 0 0 1 1 1 1 EF hand SPARC_Ca_bdg PF10591.4 KFM00961.1 - 0.031 14.3 0.1 1.9 8.5 0.0 2.4 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 KFM00961.1 - 0.043 13.4 1.2 1.3 8.7 0.1 2.5 2 0 0 2 2 2 0 EF hand ABC_tran PF00005.22 KFM00961.1 - 0.044 14.0 0.0 4.6 7.5 0.0 2.4 2 0 0 2 2 2 0 ABC transporter Arf PF00025.16 KFM00961.1 - 0.047 12.9 0.0 0.42 9.8 0.0 2.5 4 0 0 4 4 4 0 ADP-ribosylation factor family AAA_14 PF13173.1 KFM00961.1 - 0.06 13.2 0.0 5 7.0 0.0 2.7 2 1 0 2 2 2 0 AAA domain Auts2 PF15336.1 KFM00961.1 - 0.076 13.0 0.7 0.12 12.3 0.5 1.2 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein IP_trans PF02121.13 KFM00962.1 - 3.8e-33 114.7 5.3 1.3e-19 70.3 0.1 2.9 2 1 1 3 3 3 3 Phosphatidylinositol transfer protein MARVEL PF01284.18 KFM00963.1 - 1.7e-18 66.7 35.7 6.8e-10 38.9 5.9 2.1 2 0 0 2 2 2 2 Membrane-associating domain CTV_P6 PF06706.6 KFM00963.1 - 9.8 5.7 13.0 0.25 10.8 3.5 2.5 3 0 0 3 3 3 0 Citrus tristeza virus 6-kDa protein Septin PF00735.13 KFM00964.1 - 1.2e-98 329.6 0.1 1.4e-98 329.4 0.0 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KFM00964.1 - 3.7e-08 33.3 0.2 6.1e-08 32.6 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KFM00964.1 - 2e-06 27.0 0.1 3.5e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 KFM00964.1 - 2.2e-05 23.6 0.1 3.5e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 AIG1 family FtsK_SpoIIIE PF01580.13 KFM00964.1 - 0.00037 20.0 0.0 0.00068 19.1 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family Dynamin_N PF00350.18 KFM00964.1 - 0.00041 20.2 2.0 0.042 13.6 0.5 2.3 1 1 1 2 2 2 1 Dynamin family GTP_EFTU PF00009.22 KFM00964.1 - 0.00055 19.4 0.2 0.079 12.3 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 KFM00964.1 - 0.00056 20.3 0.3 0.0014 19.1 0.2 1.7 1 0 0 1 1 1 1 Miro-like protein IIGP PF05049.8 KFM00964.1 - 0.0016 17.3 0.2 0.047 12.4 0.0 2.3 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) Gtr1_RagA PF04670.7 KFM00964.1 - 0.0026 16.9 0.5 0.077 12.1 0.0 2.1 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Ras PF00071.17 KFM00964.1 - 0.0031 16.9 0.1 0.0067 15.8 0.1 1.6 1 0 0 1 1 1 1 Ras family AAA_10 PF12846.2 KFM00964.1 - 0.0031 16.9 0.0 0.0049 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain ABC_tran PF00005.22 KFM00964.1 - 0.0046 17.2 0.6 0.011 15.9 0.4 1.8 1 1 0 1 1 1 1 ABC transporter AAA_32 PF13654.1 KFM00964.1 - 0.0055 15.4 0.0 0.0092 14.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFM00964.1 - 0.011 15.7 0.1 0.023 14.6 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 KFM00964.1 - 0.013 15.6 0.1 0.036 14.2 0.0 1.8 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.1 KFM00964.1 - 0.031 13.8 0.1 0.057 12.9 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.21 KFM00964.1 - 0.05 13.0 0.3 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.1 KFM00964.1 - 0.056 13.3 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KFM00964.1 - 0.064 12.8 0.1 0.15 11.6 0.0 1.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KFM00964.1 - 0.078 13.1 0.2 0.21 11.7 0.0 1.9 2 0 0 2 2 2 0 RNA helicase DUF1542 PF07564.6 KFM00964.1 - 0.12 12.3 0.4 0.26 11.3 0.3 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) IncA PF04156.9 KFM00965.1 - 1.1e-05 25.0 15.7 2.9e-05 23.7 10.9 1.6 1 1 0 1 1 1 1 IncA protein bZIP_1 PF00170.16 KFM00965.1 - 0.0099 15.8 1.3 0.0099 15.8 0.9 3.4 1 1 1 2 2 1 1 bZIP transcription factor Sipho_Gp157 PF05565.6 KFM00965.1 - 0.018 14.6 9.7 0.034 13.7 6.1 1.7 1 1 1 2 2 2 0 Siphovirus Gp157 DUF904 PF06005.7 KFM00965.1 - 0.02 15.1 5.9 0.02 15.1 4.1 3.1 1 1 1 2 2 1 0 Protein of unknown function (DUF904) DUF4071 PF13281.1 KFM00965.1 - 0.03 13.1 5.5 0.033 13.0 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) PspA_IM30 PF04012.7 KFM00965.1 - 0.04 13.2 13.7 0.048 13.0 9.5 1.1 1 0 0 1 1 1 0 PspA/IM30 family DUF972 PF06156.8 KFM00965.1 - 0.083 13.2 14.7 2.9 8.2 6.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF1399 PF07173.7 KFM00965.1 - 0.13 12.5 1.9 0.19 12.0 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1399) LRS4 PF10422.4 KFM00965.1 - 0.2 11.0 8.3 0.23 10.7 5.8 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 AAA_23 PF13476.1 KFM00965.1 - 0.22 11.8 12.4 0.25 11.6 8.6 1.1 1 0 0 1 1 1 0 AAA domain Vac_Fusion PF02346.11 KFM00965.1 - 0.33 10.4 9.8 1.2 8.5 0.2 3.1 3 1 0 3 3 3 0 Chordopoxvirus fusion protein Nup54 PF13874.1 KFM00965.1 - 0.37 10.4 14.3 1.2 8.8 4.7 2.1 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF4200 PF13863.1 KFM00965.1 - 0.43 10.5 19.5 0.54 10.2 13.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Striatin PF08232.7 KFM00965.1 - 0.69 10.2 13.5 8.7 6.6 7.1 2.1 1 1 1 2 2 2 0 Striatin family DUF4446 PF14584.1 KFM00965.1 - 0.75 9.6 7.3 0.3 10.9 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) TMPIT PF07851.8 KFM00965.1 - 1.4 7.8 7.5 2 7.4 5.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein TMF_DNA_bd PF12329.3 KFM00965.1 - 1.5 8.6 19.6 0.26 11.1 0.6 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Atg14 PF10186.4 KFM00965.1 - 2 7.2 16.1 4 6.3 11.2 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 KFM00965.1 - 2.1 6.0 10.0 2.6 5.7 6.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ADIP PF11559.3 KFM00965.1 - 2.2 8.1 19.2 0.38 10.6 2.8 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.6 KFM00965.1 - 2.2 8.0 19.8 22 4.8 13.8 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) APG6 PF04111.7 KFM00965.1 - 2.3 7.1 19.7 3.9 6.4 13.3 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 Fib_alpha PF08702.5 KFM00965.1 - 2.5 8.2 11.5 5.5 7.1 7.9 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF2968 PF11180.3 KFM00965.1 - 2.7 7.3 14.1 1.1 8.5 6.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DUF848 PF05852.6 KFM00965.1 - 3.2 7.5 15.0 3.7 7.4 6.9 2.1 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) FlaC_arch PF05377.6 KFM00965.1 - 3.3 7.6 6.2 2.5 8.0 0.0 3.0 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Spc7 PF08317.6 KFM00965.1 - 3.6 6.1 15.6 4.1 5.9 10.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4140 PF13600.1 KFM00965.1 - 4.3 7.8 12.1 1 9.8 1.6 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Phage_Gp23 PF10669.4 KFM00965.1 - 4.3 7.4 7.7 9.4 6.3 3.4 2.2 1 1 1 2 2 2 0 Protein gp23 (Bacteriophage A118) KIAA1430 PF13879.1 KFM00965.1 - 4.3 7.8 14.1 13 6.2 9.8 1.7 1 1 0 1 1 1 0 KIAA1430 homologue DUF724 PF05266.9 KFM00965.1 - 5.4 6.5 14.7 4.6 6.8 3.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) ACCA PF03255.9 KFM00965.1 - 6.5 6.2 8.8 12 5.4 0.2 2.2 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF1664 PF07889.7 KFM00965.1 - 6.8 6.5 8.0 8.2 6.2 2.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CorA PF01544.13 KFM00965.1 - 7.9 5.4 8.5 12 4.7 5.9 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein CemA PF03040.9 KFM00965.1 - 9.1 5.8 6.2 14 5.1 4.3 1.3 1 0 0 1 1 1 0 CemA family adh_short_C2 PF13561.1 KFM00966.1 - 8.4e-29 101.0 0.0 1e-28 100.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFM00966.1 - 2.1e-17 63.5 0.2 2.7e-17 63.2 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFM00966.1 - 0.0016 18.1 0.0 0.0021 17.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Xpo1 PF08389.7 KFM00967.1 - 5.4e-28 97.7 17.7 5.4e-27 94.5 0.1 6.6 6 1 0 6 6 6 2 Exportin 1-like protein IBN_N PF03810.14 KFM00967.1 - 1.7e-07 31.0 1.5 1.7e-06 27.8 0.0 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain Pkinase PF00069.20 KFM00968.1 - 1.7e-52 178.1 0.0 2.1e-52 177.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM00968.1 - 3.9e-30 104.7 0.0 4.3e-30 104.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM00968.1 - 7.9e-09 34.8 0.0 1.5e-08 33.9 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KFM00968.1 - 0.00077 19.2 0.0 0.21 11.2 0.1 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 KFM00968.1 - 0.0022 17.0 0.0 0.0035 16.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KFM00968.1 - 0.0055 15.5 0.1 0.0099 14.7 0.0 1.4 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase MAT1 PF06391.8 KFM00971.1 - 0.23 11.0 4.5 0.36 10.3 3.1 1.4 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Ank PF00023.25 KFM00972.1 - 4.2e-41 136.7 3.6 1e-08 34.5 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_2 PF12796.2 KFM00972.1 - 2.7e-37 126.9 0.7 9.5e-14 51.5 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KFM00972.1 - 3.4e-29 97.9 0.5 7.9e-05 22.5 0.0 5.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 KFM00972.1 - 7.4e-29 99.1 0.9 2.5e-09 37.0 0.0 4.4 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFM00972.1 - 2.5e-27 94.7 0.4 6.8e-09 36.0 0.0 4.7 1 1 4 5 5 5 5 Ankyrin repeats (many copies) SAM_2 PF07647.12 KFM00972.1 - 1.3e-12 47.4 0.0 2.8e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFM00972.1 - 2e-12 47.0 0.0 3.9e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) 7tm_2 PF00002.19 KFM00973.1 - 9.4e-72 240.9 19.4 1.2e-71 240.7 13.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 KFM00973.1 - 6.1e-20 71.0 3.5 1.1e-19 70.2 2.4 1.4 1 0 0 1 1 1 1 Hormone receptor domain Dicty_CAR PF05462.6 KFM00973.1 - 0.00012 21.0 16.8 0.00017 20.6 11.6 1.1 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor PulG PF11773.3 KFM00973.1 - 1.4 8.6 3.6 0.38 10.5 0.3 1.7 2 0 0 2 2 2 0 Type II secretory pathway pseudopilin Cluap1 PF10234.4 KFM00974.1 - 8e-119 395.7 12.1 9.5e-119 395.4 8.4 1.1 1 0 0 1 1 1 1 Clusterin-associated protein-1 SseC PF04888.7 KFM00974.1 - 0.025 13.9 3.4 0.029 13.6 1.9 1.6 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family DUF848 PF05852.6 KFM00974.1 - 5.7 6.7 12.6 1.9 8.3 4.2 2.6 2 1 1 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) Atg14 PF10186.4 KFM00974.1 - 7.2 5.4 14.2 12 4.7 9.8 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 LRR_6 PF13516.1 KFM00975.1 - 9.5e-40 130.1 40.6 0.0039 17.1 0.3 15.7 14 2 1 15 15 15 12 Leucine Rich repeat NACHT PF05729.7 KFM00975.1 - 8e-30 103.6 0.0 1.8e-29 102.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain LRR_4 PF12799.2 KFM00975.1 - 5.2e-16 57.8 26.9 0.016 14.8 0.1 9.5 3 3 8 11 11 11 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM00975.1 - 2.9e-09 36.5 38.7 0.00015 21.4 0.1 7.9 4 3 5 9 9 9 6 Leucine rich repeat LRR_1 PF00560.28 KFM00975.1 - 8.1e-09 34.3 18.3 8 6.9 0.0 12.4 13 1 0 13 13 13 2 Leucine Rich Repeat FISNA PF14484.1 KFM00975.1 - 0.0068 16.3 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 Fish-specific NACHT associated domain ABC_tran PF00005.22 KFM00975.1 - 0.031 14.5 5.4 1.5 9.0 0.0 4.3 4 0 0 4 4 4 0 ABC transporter LRR_7 PF13504.1 KFM00975.1 - 0.21 11.9 24.7 46 4.8 0.0 10.8 13 0 0 13 13 13 0 Leucine rich repeat CTDII PF01556.13 KFM00976.1 - 1.2e-21 76.3 1.3 2.9e-20 71.9 0.0 2.9 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ PF00226.26 KFM00976.1 - 9.4e-15 54.1 2.4 1.5e-14 53.4 1.7 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KFM00976.1 - 1.2e-11 44.4 15.7 2.4e-11 43.4 10.9 1.5 1 0 0 1 1 1 1 DnaJ central domain WD40 PF00400.27 KFM00977.1 - 1.5e-17 62.6 0.8 9.3e-07 28.5 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat Pam16 PF03656.8 KFM00978.1 - 6.4e-42 142.3 1.5 6.9e-42 142.2 1.0 1.0 1 0 0 1 1 1 1 Pam16 PDZ_2 PF13180.1 KFM00978.1 - 0.068 13.0 0.1 0.086 12.7 0.1 1.1 1 0 0 1 1 1 0 PDZ domain HLH PF00010.21 KFM00979.1 - 6.1e-08 32.2 0.9 1.6e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Peptidase_C80 PF11713.3 KFM00979.1 - 0.06 13.1 0.5 0.26 11.1 0.3 1.9 1 1 0 1 1 1 0 Peptidase C80 family CEP19 PF14933.1 KFM00979.1 - 0.18 12.0 8.3 0.078 13.2 3.5 1.7 2 0 0 2 2 2 0 CEP19-like protein FRG2 PF15315.1 KFM00979.1 - 0.21 11.5 5.2 0.28 11.1 3.4 1.3 1 1 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Lzipper-MIP1 PF14389.1 KFM00979.1 - 1.6 8.9 20.8 4.2 7.5 10.9 2.9 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 IZUMO PF15005.1 KFM00979.1 - 1.8 8.5 6.0 0.45 10.5 1.3 2.0 2 1 1 3 3 3 0 Izumo sperm-egg fusion ADIP PF11559.3 KFM00979.1 - 8.2 6.3 21.4 1 9.2 9.5 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding CaM_binding PF07839.6 KFM00979.1 - 8.9 6.5 11.7 13 6.0 3.9 2.3 1 1 1 2 2 2 0 Plant calmodulin-binding domain Dynamin_N PF00350.18 KFM00980.1 - 2e-18 66.7 0.0 5.4e-17 62.1 0.0 2.4 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 KFM00980.1 - 6.1e-11 42.2 0.0 1.4e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KFM00980.1 - 0.018 14.2 0.0 0.16 11.1 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function, DUF258 Miro PF08477.8 KFM00980.1 - 0.029 14.8 0.0 0.6 10.6 0.0 2.5 1 1 0 1 1 1 0 Miro-like protein GTP_EFTU PF00009.22 KFM00980.1 - 0.034 13.5 0.0 0.068 12.5 0.0 1.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Guanylate_cyc PF00211.15 KFM00981.1 - 5.3e-61 205.2 0.2 7.6e-61 204.6 0.2 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain API5 PF05918.6 KFM00981.1 - 1.2 7.4 3.5 2 6.8 2.4 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Guanylate_cyc PF00211.15 KFM00982.1 - 1.8e-52 177.3 0.0 2.5e-52 176.9 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain KAT11 PF08214.6 KFM00983.1 - 3.2e-79 266.5 0.9 6e-79 265.6 0.6 1.4 1 0 0 1 1 1 1 Histone acetylation protein KIX PF02172.11 KFM00983.1 - 4.6e-42 141.9 0.9 1.4e-41 140.3 0.6 1.9 1 0 0 1 1 1 1 KIX domain zf-TAZ PF02135.11 KFM00983.1 - 5.7e-35 119.1 66.4 9.6e-21 73.5 13.5 3.5 3 0 0 3 3 3 2 TAZ zinc finger Creb_binding PF09030.5 KFM00983.1 - 2.7e-32 111.0 16.2 2.7e-32 111.0 11.2 12.7 6 3 9 15 15 15 1 Creb binding DUF902 PF06001.8 KFM00983.1 - 3.3e-24 84.7 8.1 3.3e-24 84.7 5.6 2.3 2 0 0 2 2 2 1 Domain of Unknown Function (DUF902) Bromodomain PF00439.20 KFM00983.1 - 2.2e-18 65.9 0.0 5.5e-18 64.6 0.0 1.7 1 0 0 1 1 1 1 Bromodomain ZZ PF00569.12 KFM00983.1 - 2.3e-14 52.6 14.2 2.3e-14 52.6 9.8 3.5 4 0 0 4 4 4 1 Zinc finger, ZZ type Npa1 PF11707.3 KFM00983.1 - 0.00047 19.2 0.0 0.00086 18.3 0.0 1.3 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal HSP90 PF00183.13 KFM00984.1 - 2.6e-80 270.3 5.7 2.2e-76 257.3 1.7 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.1 KFM00984.1 - 3.4e-13 49.4 0.1 1.3e-12 47.5 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KFM00984.1 - 1.9e-08 34.0 0.1 3.9e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BTB PF00651.26 KFM00985.1 - 4.9e-12 45.8 0.0 8.2e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Slx4 PF09494.5 KFM00986.1 - 2.2e-18 65.7 0.1 3.4e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Slx4 endonuclease SAP PF02037.22 KFM00986.1 - 0.12 11.9 0.5 3.6 7.1 0.0 2.4 2 0 0 2 2 2 0 SAP domain zf-H2C2_2 PF13465.1 KFM00987.1 - 3.2e-54 178.6 36.0 3.2e-11 42.9 0.3 7.0 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.21 KFM00987.1 - 7.4e-42 139.2 40.2 8.7e-08 32.0 0.7 7.1 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KFM00987.1 - 4.3e-22 77.2 30.7 4.3e-07 29.6 0.1 7.3 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KFM00987.1 - 1.7e-20 71.7 39.1 4.4e-05 23.5 0.3 7.1 7 0 0 7 7 7 6 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 KFM00987.1 - 7.4e-11 41.8 18.6 0.33 10.9 0.0 6.1 5 1 0 5 5 5 4 Zinc ribbon domain zf-C2H2_jaz PF12171.3 KFM00987.1 - 2.5e-09 37.0 12.0 0.17 12.0 0.1 6.2 7 0 0 7 7 6 2 Zinc-finger double-stranded RNA-binding XPA_N PF01286.13 KFM00987.1 - 2.3e-08 33.5 14.4 1.5 8.5 0.2 6.1 6 0 0 6 6 6 2 XPA protein N-terminal C1_1 PF00130.17 KFM00987.1 - 1.9e-07 30.6 12.1 0.054 13.2 0.3 4.3 1 1 5 6 6 6 5 Phorbol esters/diacylglycerol binding domain (C1 domain) DNA_RNApol_7kD PF03604.8 KFM00987.1 - 2.9e-06 26.6 18.5 3.1 7.3 0.1 6.2 6 0 0 6 6 6 0 DNA directed RNA polymerase, 7 kDa subunit zf-trcl PF13451.1 KFM00987.1 - 9e-06 25.2 14.0 0.76 9.4 0.1 6.1 6 0 0 6 6 6 1 Probable zinc-binding domain zinc_ribbon_5 PF13719.1 KFM00987.1 - 1.2e-05 24.7 12.0 1.4 8.5 0.0 5.9 4 1 1 5 5 5 1 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KFM00987.1 - 2.2e-05 24.0 10.8 1.7 8.4 0.0 5.9 5 1 1 6 6 6 1 zinc-ribbon domain TFIIS_C PF01096.13 KFM00987.1 - 3e-05 23.5 21.2 4.1 7.1 0.1 6.1 5 1 0 5 5 5 0 Transcription factor S-II (TFIIS) Imm-NTF2-2 PF15631.1 KFM00987.1 - 5.1e-05 23.1 0.0 6.1 6.9 0.0 5.1 2 1 4 6 6 5 0 NTF2 fold immunity protein C1_4 PF07975.7 KFM00987.1 - 8.1e-05 22.5 17.0 0.24 11.4 1.6 5.1 1 1 5 6 6 6 3 TFIIH C1-like domain Zn_Tnp_IS1595 PF12760.2 KFM00987.1 - 0.00033 20.4 29.5 1.3 8.8 3.9 5.2 3 1 2 5 5 5 3 Transposase zinc-ribbon domain YhfH PF14149.1 KFM00987.1 - 0.00067 19.3 21.0 1.3 8.8 0.3 6.1 6 0 0 6 6 6 1 YhfH-like protein CpXC PF14353.1 KFM00987.1 - 0.00072 19.5 13.1 6.8 6.6 0.1 5.9 6 0 0 6 6 6 0 CpXC protein zf-CHY PF05495.7 KFM00987.1 - 0.0011 19.0 16.9 0.049 13.7 4.0 2.9 1 1 2 3 3 3 3 CHY zinc finger Elf1 PF05129.8 KFM00987.1 - 0.0018 17.9 11.1 0.24 11.1 0.5 3.9 1 1 4 5 5 5 3 Transcription elongation factor Elf1 like FYDLN_acid PF09538.5 KFM00987.1 - 0.0019 18.7 8.7 25 5.5 0.9 5.6 1 1 4 5 5 5 0 Protein of unknown function (FYDLN_acid) LIM PF00412.17 KFM00987.1 - 0.0033 17.4 17.3 0.93 9.6 1.3 4.7 2 2 3 5 5 5 2 LIM domain Zn_ribbon_recom PF13408.1 KFM00987.1 - 0.0035 17.5 15.9 4.7 7.5 1.4 5.6 1 1 3 4 4 4 0 Recombinase zinc beta ribbon domain zf-UBP PF02148.14 KFM00987.1 - 0.0042 17.1 19.5 14 5.8 2.5 5.2 1 1 4 5 5 5 0 Zn-finger in ubiquitin-hydrolases and other protein zf-CSL PF05207.8 KFM00987.1 - 0.0062 16.0 17.3 0.61 9.6 1.1 4.6 1 1 3 4 4 4 3 CSL zinc finger C1_3 PF07649.7 KFM00987.1 - 0.007 16.3 14.7 20 5.2 0.1 5.9 6 0 0 6 6 6 0 C1-like domain Ribosomal_L44 PF00935.14 KFM00987.1 - 0.014 15.3 19.7 6.4 6.8 0.2 5.5 1 1 4 5 5 5 0 Ribosomal protein L44 zf-H2C2_5 PF13909.1 KFM00987.1 - 0.019 15.1 0.3 0.019 15.1 0.2 7.4 7 2 0 7 7 6 0 C2H2-type zinc-finger domain zf-LYAR PF08790.6 KFM00987.1 - 0.024 14.3 16.3 5.9 6.6 0.0 6.0 6 0 0 6 6 6 0 LYAR-type C2HC zinc finger zf-ribbon_3 PF13248.1 KFM00987.1 - 0.031 13.5 19.6 4.2 6.6 0.1 6.0 6 0 0 6 6 6 0 zinc-ribbon domain UPF0547 PF10571.4 KFM00987.1 - 0.048 13.3 23.0 2.4 7.9 0.1 6.0 6 0 0 6 6 6 0 Uncharacterised protein family UPF0547 zf-AN1 PF01428.11 KFM00987.1 - 0.062 13.1 22.6 13 5.7 0.1 6.2 5 1 1 6 6 6 0 AN1-like Zinc finger HypA PF01155.14 KFM00987.1 - 0.062 12.9 16.2 1.8 8.3 0.3 3.6 1 1 2 3 3 3 0 Hydrogenase expression/synthesis hypA family DUF2688 PF10892.3 KFM00987.1 - 0.073 12.7 9.0 29 4.3 0.0 5.4 5 1 1 6 6 6 0 Protein of unknown function (DUF2688) Siva PF05458.7 KFM00987.1 - 0.15 11.6 6.0 3.3 7.2 0.2 2.3 1 1 2 3 3 3 0 Cd27 binding protein (Siva) Pombe_5TM PF09437.5 KFM00987.1 - 0.17 11.3 0.3 17 4.6 0.0 2.6 1 1 2 3 3 3 0 Pombe specific 5TM protein zinc_ribbon_2 PF13240.1 KFM00987.1 - 0.18 11.3 23.6 1.4 8.4 2.7 5.5 5 1 0 5 5 5 0 zinc-ribbon domain GATA PF00320.22 KFM00987.1 - 0.41 10.0 15.1 36 3.8 0.7 5.7 4 1 1 5 5 5 0 GATA zinc finger A2L_zn_ribbon PF08792.5 KFM00987.1 - 0.74 9.3 26.3 9.6 5.8 0.2 6.0 6 0 0 6 6 6 0 A2L zinc ribbon domain zf-ISL3 PF14690.1 KFM00987.1 - 0.86 9.6 17.2 33 4.6 0.1 6.3 6 0 0 6 6 6 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DUF2321 PF10083.4 KFM00987.1 - 1 8.8 14.8 10 5.5 0.0 4.7 1 1 3 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-met PF12874.2 KFM00987.1 - 1.3 9.3 24.3 11 6.4 0.1 6.1 6 0 0 6 6 6 0 Zinc-finger of C2H2 type DUF2072 PF09845.4 KFM00987.1 - 1.5 8.7 17.2 5.1 7.0 0.1 5.3 4 1 2 6 6 6 0 Zn-ribbon containing protein (DUF2072) Fer4_17 PF13534.1 KFM00987.1 - 1.8 8.9 16.1 31 5.0 0.1 5.5 4 2 2 6 6 6 0 4Fe-4S dicluster domain zf-RING_3 PF14369.1 KFM00987.1 - 1.9 8.5 19.5 5.5 7.0 0.1 5.7 5 1 1 6 6 6 0 zinc-finger zf-HYPF PF07503.7 KFM00987.1 - 3 7.3 27.0 15 5.0 0.1 6.4 5 2 1 6 6 6 0 HypF finger DUF2256 PF10013.4 KFM00987.1 - 3 7.6 18.0 0.78 9.5 0.2 5.4 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-Mss51 PF13824.1 KFM00987.1 - 3.3 7.6 28.3 1.3 8.9 0.4 5.9 2 2 3 5 5 5 0 Zinc-finger of mitochondrial splicing suppressor 51 BolA PF01722.13 KFM00987.1 - 3.9 7.5 9.1 2.3 8.2 0.2 3.7 1 1 3 4 4 4 0 BolA-like protein FYVE PF01363.16 KFM00987.1 - 5 7.0 27.1 19 5.2 1.9 4.8 1 1 2 3 3 2 0 FYVE zinc finger Yippee-Mis18 PF03226.9 KFM00987.1 - 6.1 6.9 14.4 2.6 8.1 1.7 4.0 1 1 4 5 5 5 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly BRCA2 PF00634.13 KFM00987.1 - 8.8 5.7 13.8 7.3 5.9 0.1 4.9 6 0 0 6 6 6 0 BRCA2 repeat Evr1_Alr PF04777.8 KFM00987.1 - 9.1 6.2 20.7 5.7 6.9 0.3 5.4 1 1 5 6 6 6 0 Erv1 / Alr family DUF2387 PF09526.5 KFM00987.1 - 9.1 6.2 18.1 7.9 6.4 1.1 4.8 1 1 3 5 5 5 0 Probable metal-binding protein (DUF2387) Heme_oxygenase PF01126.15 KFM00988.1 - 5.4e-83 277.5 5.4 6.4e-83 277.3 3.7 1.1 1 0 0 1 1 1 1 Heme oxygenase zf-LITAF-like PF10601.4 KFM00989.1 - 2.3e-22 78.6 15.7 3.1e-22 78.2 10.8 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain FANCI_S1-cap PF14674.1 KFM00990.1 - 0.33 11.0 2.0 2.2 8.3 0.4 2.4 1 1 1 2 2 2 0 FANCI solenoid 1 cap zf-C3HC4_3 PF13920.1 KFM00991.1 - 1.2e-14 53.6 8.9 1.9e-14 53.0 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM00991.1 - 1.2e-07 31.5 12.1 2e-07 30.8 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM00991.1 - 1.4e-05 24.8 11.9 2.4e-05 24.0 8.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KFM00991.1 - 0.00042 19.9 9.9 0.00074 19.2 6.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.1 KFM00991.1 - 0.014 14.9 6.1 0.028 13.9 4.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 KFM00991.1 - 0.98 9.0 8.0 1.7 8.3 5.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.9 KFM00991.1 - 5.8 6.4 12.8 16 5.0 8.9 1.7 1 1 0 1 1 1 0 P-11 zinc finger Acetyltransf_1 PF00583.19 KFM00993.1 - 2.9e-13 49.6 0.0 4.1e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFM00993.1 - 4.1e-09 36.4 0.0 6.3e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFM00993.1 - 1.2e-06 28.1 0.0 2.1e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KFM00993.1 - 0.052 13.6 0.0 0.086 12.9 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFM00993.1 - 0.13 12.1 0.0 2.6 7.9 0.0 2.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4507 PF14964.1 KFM00994.1 - 1.7e-112 375.7 1.3 2.1e-112 375.4 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4507) Exo_endo_phos PF03372.18 KFM00995.1 - 3e-07 30.6 0.0 4e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KFM00995.1 - 0.0012 18.4 0.0 0.0027 17.2 0.0 1.6 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase NanE PF04131.9 KFM00995.1 - 0.1 11.5 0.0 0.19 10.6 0.0 1.4 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Exo_endo_phos PF03372.18 KFM00996.1 - 8.2e-12 45.5 0.1 9.5e-12 45.3 0.1 1.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KFM00996.1 - 0.02 14.5 0.1 0.092 12.3 0.1 2.2 2 1 0 2 2 2 0 Endonuclease-reverse transcriptase ECH PF00378.15 KFM00997.1 - 3.1e-70 236.1 0.0 3.6e-70 235.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Voltage_CLC PF00654.15 KFM00998.1 - 1.5e-93 313.6 24.7 1.5e-93 313.6 17.1 2.0 1 1 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 KFM00998.1 - 2.7e-09 36.6 0.1 0.0014 18.3 0.0 3.1 2 1 0 2 2 2 2 CBS domain LUC7 PF03194.10 KFM00999.1 - 3.5e-81 272.4 25.6 3.5e-81 272.4 17.7 2.2 2 1 0 2 2 2 1 LUC7 N_terminus Spore_III_AB PF09548.5 KFM00999.1 - 3.7 7.2 7.2 1.3 8.8 2.6 1.9 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) PQQ_2 PF13360.1 KFM01000.1 - 5e-05 22.8 0.4 0.02 14.3 0.1 2.7 2 1 0 2 2 2 2 PQQ-like domain FG-GAP PF01839.18 KFM01000.1 - 0.0036 16.9 0.1 0.11 12.1 0.1 2.6 2 0 0 2 2 2 1 FG-GAP repeat PQQ PF01011.16 KFM01000.1 - 0.0061 16.0 0.2 0.14 11.7 0.0 2.9 3 0 0 3 3 3 1 PQQ enzyme repeat VCBS PF13517.1 KFM01000.1 - 0.018 15.4 0.2 1 9.7 0.0 2.7 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DIX PF00778.12 KFM01001.1 - 2.1e-31 107.4 0.8 3.6e-31 106.7 0.6 1.4 1 0 0 1 1 1 1 DIX domain RGS PF00615.14 KFM01001.1 - 2e-27 95.6 0.5 4.2e-27 94.5 0.3 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain Axin_b-cat_bind PF08833.5 KFM01001.1 - 1.2e-18 66.5 2.7 3.3e-18 65.0 1.9 1.9 1 0 0 1 1 1 1 Axin beta-catenin binding domain DUF3522 PF12036.3 KFM01002.1 - 3.3e-65 219.3 19.0 7e-65 218.3 13.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) Globin PF00042.17 KFM01003.1 - 2.5e-31 108.2 0.6 3.3e-31 107.8 0.4 1.2 1 0 0 1 1 1 1 Globin Globin PF00042.17 KFM01005.1 - 5.8e-30 103.8 0.0 8e-30 103.4 0.0 1.2 1 0 0 1 1 1 1 Globin NPR3 PF03666.8 KFM01006.1 - 1.1e-95 320.8 11.6 1.6e-83 280.7 4.9 3.1 2 1 1 3 3 3 2 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.6 KFM01006.1 - 0.00045 19.0 0.2 0.49 9.0 0.0 2.3 2 1 0 2 2 2 2 Nitrogen permease regulator 2 Pur_DNA_glyco PF02245.11 KFM01007.1 - 1e-59 200.7 0.0 1.3e-59 200.4 0.0 1.1 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) Rhomboid_SP PF12595.3 KFM01008.1 - 1.9e-106 354.3 1.5 1.9e-106 354.3 1.1 1.6 2 0 0 2 2 2 1 Rhomboid serine protease Rhomboid PF01694.17 KFM01008.1 - 2.6e-30 105.3 10.2 5.4e-30 104.3 7.1 1.5 1 0 0 1 1 1 1 Rhomboid family B-block_TFIIIC PF04182.7 KFM01009.1 - 4.4e-19 68.1 0.1 4.9e-18 64.7 0.0 2.9 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC DUF4457 PF14652.1 KFM01010.1 - 4.8e-196 650.2 0.5 2.1e-135 450.9 0.0 4.7 3 2 1 4 4 4 4 Domain of unknown function (DUF4457) Sad1_UNC PF07738.8 KFM01010.1 - 7.2e-06 25.8 0.0 1.4 8.7 0.0 4.9 5 0 0 5 5 5 2 Sad1 / UNC-like C-terminal GSG-1 PF07803.6 KFM01011.1 - 1.5e-51 172.9 0.6 2.6e-51 172.1 0.4 1.4 1 0 0 1 1 1 1 GSG1-like protein Claudin_2 PF13903.1 KFM01011.1 - 8.7e-10 38.5 8.3 2.1e-09 37.2 5.7 1.6 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 KFM01011.1 - 2.2e-07 30.7 13.4 4.6e-07 29.6 3.3 2.5 1 1 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family Tissue_fac PF01108.12 KFM01012.1 - 9.8e-22 76.7 0.0 1.1e-20 73.3 0.0 2.3 2 0 0 2 2 2 1 Tissue factor Interfer-bind PF09294.5 KFM01012.1 - 2.8e-11 43.3 0.6 7.8e-11 41.9 0.1 2.0 2 1 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.16 KFM01012.1 - 6.5e-05 22.9 0.2 0.082 13.0 0.1 2.6 2 1 0 2 2 2 2 Fibronectin type III domain Fox-1_C PF12414.3 KFM01013.1 - 2.6e-41 139.9 22.0 2.6e-41 139.9 15.2 2.8 3 0 0 3 3 3 1 Calcitonin gene-related peptide regulator C terminal RRM_1 PF00076.17 KFM01013.1 - 9e-19 66.8 0.1 1.7e-18 65.9 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM01013.1 - 2.4e-15 56.2 0.1 4.3e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM01013.1 - 4.3e-11 42.4 0.2 1.8e-10 40.5 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFM01013.1 - 0.065 13.0 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif Claudin_2 PF13903.1 KFM01014.1 - 8.2e-14 51.6 9.2 9.5e-14 51.4 6.4 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 KFM01014.1 - 3.6e-07 29.9 5.2 5.2e-07 29.4 3.6 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family AA_permease_C PF13906.1 KFM01014.1 - 0.19 11.6 8.9 0.059 13.2 2.7 2.3 2 0 0 2 2 2 0 C-terminus of AA_permease Tetraspannin PF00335.15 KFM01014.1 - 0.32 10.2 4.9 0.49 9.6 3.4 1.4 1 0 0 1 1 1 0 Tetraspanin family DUF2244 PF10003.4 KFM01014.1 - 2.9 7.2 8.4 0.46 9.8 3.0 1.7 1 1 0 1 1 1 0 Integral membrane protein (DUF2244) zf-DHHC PF01529.15 KFM01014.1 - 5.3 6.4 6.0 21 4.4 4.3 1.8 1 1 1 2 2 2 0 DHHC palmitoyltransferase PsbN PF02468.10 KFM01014.1 - 5.5 6.6 7.4 2.5 7.7 2.5 2.4 1 1 2 3 3 3 0 Photosystem II reaction centre N protein (psbN) Methyltransf_16 PF10294.4 KFM01015.1 - 4.6e-21 75.0 0.9 3.6e-19 68.8 0.6 2.2 1 1 0 1 1 1 1 Putative methyltransferase RrnaAD PF00398.15 KFM01015.1 - 0.026 13.5 0.0 0.1 11.6 0.0 1.8 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase MTS PF05175.9 KFM01015.1 - 0.038 13.3 0.0 0.098 12.0 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_26 PF13659.1 KFM01015.1 - 0.039 14.0 0.0 0.068 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KFM01015.1 - 0.047 14.2 0.0 0.13 12.8 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 KFM01015.1 - 0.11 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TMEM223 PF14640.1 KFM01016.1 - 1.5e-05 25.0 0.1 2e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Transmembrane protein 223 DUF2627 PF11118.3 KFM01016.1 - 0.032 14.3 0.3 0.069 13.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) PMM PF03332.8 KFM01017.1 - 1.6e-110 367.9 0.8 1.8e-110 367.7 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase SBP_bac_6 PF13343.1 KFM01017.1 - 0.074 12.3 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein DUF600 PF04634.7 KFM01017.1 - 0.11 12.4 0.0 0.29 11.1 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function, DUF600 CSD PF00313.17 KFM01018.1 - 6.2e-13 48.3 0.0 8.5e-13 47.8 0.0 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.6 KFM01018.1 - 0.0018 17.7 0.0 0.003 17.0 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease B OB domain USP7_ICP0_bdg PF12436.3 KFM01019.1 - 5.2e-79 264.9 0.0 4.5e-78 261.9 0.0 2.3 1 1 1 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 KFM01019.1 - 4.7e-70 235.3 5.3 1.3e-66 224.0 2.4 3.4 3 0 0 3 3 3 2 Ubiquitin-specific protease C-terminal UCH PF00443.24 KFM01019.1 - 8.7e-58 195.5 0.6 1.6e-57 194.6 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFM01019.1 - 7.5e-27 94.5 0.0 1.5e-26 93.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 KFM01019.1 - 3.7e-17 62.6 1.5 1.7e-16 60.5 0.2 2.8 3 1 0 3 3 3 1 MATH domain DUF4588 PF15251.1 KFM01020.1 - 2.6e-46 158.4 0.0 3e-46 158.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4588) DUF3678 PF12435.3 KFM01020.1 - 0.097 12.2 0.1 0.2 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) AChE_tetra PF08674.5 KFM01021.1 - 0.48 9.9 8.4 0.53 9.8 0.7 2.8 2 0 0 2 2 2 0 Acetylcholinesterase tetramerisation domain Gryzun PF07919.7 KFM01022.1 - 0.044 12.1 0.0 0.053 11.8 0.0 1.1 1 0 0 1 1 1 0 Gryzun, putative trafficking through Golgi Bcl-2 PF00452.14 KFM01023.1 - 1.1e-13 51.1 0.0 1.4e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family Bclx_interact PF08945.5 KFM01023.1 - 0.09 12.3 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 Bcl-x interacting, BH3 domain PT PF04886.7 KFM01024.1 - 0.85 8.9 0.0 0.85 8.9 0.0 5.1 2 1 0 2 2 2 0 PT repeat DUF1777 PF08648.7 KFM01025.1 - 3.6e-35 121.3 35.1 4e-35 121.1 24.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) Corona_nucleoca PF00937.13 KFM01025.1 - 0.84 8.5 16.7 0.89 8.4 11.6 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF4614 PF15391.1 KFM01025.1 - 1.6 8.4 9.1 2 8.1 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) TT_ORF1 PF02956.9 KFM01025.1 - 3.3 6.0 19.9 3.1 6.1 13.8 1.2 1 0 0 1 1 1 0 TT viral orf 1 DUF566 PF04484.7 KFM01025.1 - 4.5 6.6 12.4 4.4 6.7 8.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) MIP-T3 PF10243.4 KFM01025.1 - 8.2 4.7 22.7 8.1 4.7 15.7 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Glyco_hydro_31 PF01055.21 KFM01027.1 - 6.5e-174 578.8 3.9 1.1e-156 522.1 0.6 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 31 Trefoil PF00088.13 KFM01027.1 - 4.4e-08 32.6 2.6 7.3e-08 31.9 1.8 1.3 1 0 0 1 1 1 1 Trefoil (P-type) domain Gal_mutarotas_2 PF13802.1 KFM01027.1 - 0.00013 21.7 1.4 0.00035 20.3 1.0 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like C1q PF00386.16 KFM01028.1 - 2.7e-33 114.6 0.0 3.3e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 KFM01028.1 - 1.2e-10 40.7 32.1 9.9e-09 34.6 22.3 2.1 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) NMD3 PF04981.8 KFM01029.1 - 1.1e-76 257.0 6.5 1.8e-76 256.3 4.5 1.4 1 0 0 1 1 1 1 NMD3 family DZR PF12773.2 KFM01029.1 - 0.069 12.9 8.5 0.15 11.9 4.0 2.6 2 1 0 2 2 2 0 Double zinc ribbon DUF1289 PF06945.8 KFM01029.1 - 0.07 12.6 2.0 2.8 7.4 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1289) TMEM37 PF15108.1 KFM01029.1 - 0.11 12.1 0.2 0.24 11.0 0.1 1.5 1 1 0 1 1 1 0 Voltage-dependent calcium channel gamma-like subunit protein family DUF3317 PF11779.3 KFM01030.1 - 7.4e-13 47.7 10.2 8.9e-13 47.4 7.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) Ion_trans_N PF08412.5 KFM01030.1 - 6 6.2 6.4 4.2 6.7 3.3 1.6 1 1 0 1 1 1 0 Ion transport protein N-terminal PP2C PF00481.16 KFM01031.1 - 1.5e-58 198.1 0.0 2e-58 197.7 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KFM01031.1 - 8.7e-10 38.3 0.0 1.6e-09 37.5 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KFM01031.1 - 0.00031 20.5 0.0 0.0042 16.8 0.0 2.2 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Arm PF00514.18 KFM01032.1 - 5.6e-89 289.2 20.8 9.4e-14 50.6 0.2 9.8 10 0 0 10 10 10 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFM01032.1 - 2.6e-25 88.5 0.0 1.7e-08 34.5 0.0 5.7 2 2 3 5 5 5 4 HEAT repeats HEAT PF02985.17 KFM01032.1 - 2.6e-19 67.5 4.9 0.0014 18.5 0.0 7.5 8 0 0 8 8 8 3 HEAT repeat IBB PF01749.15 KFM01032.1 - 2.4e-17 62.8 2.9 4.6e-17 61.9 2.0 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 KFM01032.1 - 1.3e-16 60.5 5.2 2.1e-06 28.0 0.0 6.3 3 3 5 8 8 8 5 HEAT-like repeat Adaptin_N PF01602.15 KFM01032.1 - 6.4e-08 31.3 2.0 4e-07 28.7 1.4 2.2 1 1 0 1 1 1 1 Adaptin N terminal region Arm_2 PF04826.8 KFM01032.1 - 1.4e-06 27.6 1.2 0.046 12.8 0.2 3.5 2 1 0 3 3 3 2 Armadillo-like V-ATPase_H_C PF11698.3 KFM01032.1 - 4.9e-06 26.4 0.5 1.1 9.2 0.1 4.3 4 1 1 5 5 5 3 V-ATPase subunit H V-ATPase_H_N PF03224.9 KFM01032.1 - 4.7e-05 22.6 1.4 0.0013 17.9 0.4 2.6 1 1 0 2 2 2 1 V-ATPase subunit H Atx10homo_assoc PF09759.4 KFM01032.1 - 0.00037 20.1 0.2 5.5 6.7 0.1 4.3 2 1 1 4 4 4 2 Spinocerebellar ataxia type 10 protein domain Proteasom_PSMB PF10508.4 KFM01032.1 - 0.0055 15.0 0.9 0.19 9.9 0.1 3.1 2 2 1 3 3 3 1 Proteasome non-ATPase 26S subunit Mo25 PF08569.6 KFM01032.1 - 0.023 13.7 0.1 0.078 11.9 0.0 1.9 1 1 0 1 1 1 0 Mo25-like Cnd3 PF12719.2 KFM01032.1 - 0.044 12.7 0.2 5.1 5.9 0.0 3.7 2 2 1 4 4 4 0 Nuclear condensing complex subunits, C-term domain RasGEF_N_2 PF14663.1 KFM01032.1 - 0.064 13.1 0.2 1 9.3 0.0 2.8 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF1981 PF09324.5 KFM01032.1 - 0.093 12.2 0.3 1.6 8.2 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1981) CTNNBL PF08216.6 KFM01032.1 - 0.12 11.9 7.1 11 5.6 0.2 4.8 5 1 1 6 6 6 0 Catenin-beta-like, Arm-motif containing nuclear zf-RING_2 PF13639.1 KFM01033.1 - 4.7e-09 35.9 7.3 4.7e-09 35.9 5.1 2.3 2 0 0 2 2 2 1 Ring finger domain zf-B_box PF00643.19 KFM01033.1 - 1.7e-08 34.2 1.0 1.7e-08 34.2 0.7 3.3 4 0 0 4 4 4 1 B-box zinc finger zf-C3HC4 PF00097.20 KFM01033.1 - 1e-07 31.4 6.1 1e-07 31.4 4.2 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM01033.1 - 1.5e-07 30.9 4.3 1.5e-07 30.9 2.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM01033.1 - 1.6e-07 31.2 8.0 1.6e-07 31.2 5.5 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFM01033.1 - 3.9e-07 29.8 5.4 3.9e-07 29.8 3.8 3.0 2 2 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KFM01033.1 - 5.1e-07 29.3 3.9 5.1e-07 29.3 2.7 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 KFM01033.1 - 7e-07 28.8 5.2 7e-07 28.8 3.6 2.4 2 1 0 2 2 2 1 zinc-RING finger domain U-box PF04564.10 KFM01033.1 - 0.0026 17.6 0.1 0.029 14.3 0.1 2.4 1 1 0 1 1 1 1 U-box domain DUF349 PF03993.7 KFM01033.1 - 0.0028 17.7 0.4 0.0085 16.2 0.3 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF349) zf-RING_6 PF14835.1 KFM01033.1 - 0.0044 16.7 1.9 0.0044 16.7 1.3 2.5 3 0 0 3 3 3 1 zf-RING of BARD1-type protein DEAD PF00270.24 KFM01033.1 - 0.033 13.6 1.3 0.058 12.8 0.9 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase DUF1633 PF07794.6 KFM01033.1 - 0.041 11.8 0.0 0.052 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) zf-RING_4 PF14570.1 KFM01033.1 - 0.13 11.8 4.3 0.79 9.3 3.0 2.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 KFM01033.1 - 0.22 11.1 6.1 0.28 10.7 1.6 2.8 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 DASH_Dad3 PF08656.5 KFM01033.1 - 0.24 11.1 5.1 0.079 12.6 0.9 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad3 SMC_N PF02463.14 KFM01034.1 - 7.9e-73 244.3 28.0 1.8e-72 243.1 19.4 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KFM01034.1 - 1.9e-24 85.9 3.9 3e-24 85.2 0.0 3.0 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KFM01034.1 - 1.3e-12 48.2 5.4 2.5e-07 30.9 0.1 4.3 2 2 1 4 4 4 2 AAA domain AAA_29 PF13555.1 KFM01034.1 - 8.5e-05 21.9 0.0 0.00017 21.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 KFM01034.1 - 0.0029 16.1 123.7 0.031 12.7 24.3 5.5 3 2 2 5 5 5 4 AAA domain Vac_Fusion PF02346.11 KFM01034.1 - 0.035 13.5 11.9 0.055 12.8 0.1 5.0 3 0 0 3 3 3 0 Chordopoxvirus fusion protein SHNi-TPR PF10516.4 KFM01034.1 - 0.21 10.8 6.4 1.1 8.5 0.1 3.7 4 0 0 4 4 4 0 SHNi-TPR Reo_sigmaC PF04582.7 KFM01034.1 - 0.47 9.5 40.2 1.2 8.1 1.6 5.8 2 2 4 6 6 6 0 Reovirus sigma C capsid protein WD40 PF00400.27 KFM01035.1 - 1.1e-20 72.6 9.9 0.00011 21.9 0.0 6.9 6 0 0 6 6 6 6 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KFM01035.1 - 0.012 14.3 3.0 0.027 13.2 1.0 2.3 2 1 0 2 2 2 0 Coatomer WD associated region PQQ_3 PF13570.1 KFM01035.1 - 0.11 12.8 0.2 27 5.2 0.0 3.9 3 0 0 3 3 3 0 PQQ-like domain FIIND PF13553.1 KFM01036.1 - 1.3e-23 83.7 0.0 1.5e-23 83.5 0.0 1.0 1 0 0 1 1 1 1 Function to find SCHIP-1 PF10148.4 KFM01037.1 - 5.5e-123 408.9 15.9 6.1e-123 408.7 11.0 1.0 1 0 0 1 1 1 1 Schwannomin-interacting protein 1 FEZ PF07763.8 KFM01037.1 - 0.00011 21.9 7.6 0.00023 20.9 5.3 1.6 1 1 0 1 1 1 1 FEZ-like protein FAM117 PF15388.1 KFM01037.1 - 0.8 8.8 7.2 1.7 7.7 5.0 1.5 1 1 0 1 1 1 0 Protein Family FAM117 IQ-like PF15157.1 KFM01038.1 - 1.8e-46 156.2 2.9 2.1e-46 156.0 2.0 1.0 1 0 0 1 1 1 1 IQ-like IQ PF00612.22 KFM01038.1 - 0.013 15.0 0.1 0.024 14.2 0.1 1.4 1 0 0 1 1 1 0 IQ calmodulin-binding motif MFS_1 PF07690.11 KFM01039.1 - 2.1e-39 135.2 68.6 4.7e-28 97.9 25.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFM01039.1 - 0.00029 19.3 25.7 0.00029 19.3 17.8 2.8 1 1 2 3 3 3 1 MFS/sugar transport protein Sugar_tr PF00083.19 KFM01039.1 - 0.033 12.7 38.8 0.061 11.8 26.9 1.4 1 1 0 1 1 1 0 Sugar (and other) transporter Latexin PF06907.7 KFM01040.1 - 9.5e-77 257.0 0.4 1.1e-76 256.9 0.3 1.0 1 0 0 1 1 1 1 Latexin GTP_EFTU PF00009.22 KFM01041.1 - 2.1e-61 206.6 0.0 3.1e-61 206.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KFM01041.1 - 4.4e-33 113.3 0.1 1.4e-32 111.7 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.1 KFM01041.1 - 4.5e-31 106.5 0.0 9.7e-31 105.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 KFM01041.1 - 2.6e-24 84.8 0.0 6.8e-24 83.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KFM01041.1 - 9.9e-15 54.4 0.0 2.6e-14 53.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KFM01041.1 - 0.0063 16.4 0.1 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 KFM01041.1 - 0.016 14.3 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 AIG1 family SRPRB PF09439.5 KFM01041.1 - 0.11 11.6 0.0 0.39 9.9 0.0 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Latexin PF06907.7 KFM01042.1 - 1.4e-57 194.3 1.1 1.6e-57 194.2 0.7 1.0 1 0 0 1 1 1 1 Latexin Mlf1IP PF10248.4 KFM01043.1 - 2.3e-78 261.8 7.2 2.7e-78 261.6 5.0 1.0 1 0 0 1 1 1 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein Pro_CA PF00484.14 KFM01044.1 - 0.012 15.6 0.6 0.032 14.2 0.4 1.7 1 0 0 1 1 1 0 Carbonic anhydrase Homeobox PF00046.24 KFM01045.1 - 1e-13 50.6 0.4 1.3e-13 50.3 0.3 1.2 1 0 0 1 1 1 1 Homeobox domain PQ-loop PF04193.9 KFM01046.1 - 6.5e-19 67.2 0.8 6.5e-19 67.2 0.6 2.2 3 0 0 3 3 3 1 PQ loop repeat DUF2427 PF10348.4 KFM01046.1 - 0.13 11.8 0.5 0.3 10.6 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF2427) 7TM_GPCR_Srh PF10318.4 KFM01046.1 - 0.14 10.9 2.4 0.37 9.5 0.2 2.2 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srh MtN3_slv PF03083.11 KFM01046.1 - 2 8.3 6.6 0.19 11.6 0.2 2.3 3 0 0 3 3 3 0 Sugar efflux transporter for intercellular exchange PH PF00169.24 KFM01047.1 - 1.4e-11 44.5 2.9 1.4e-11 44.4 0.3 2.4 3 0 0 3 3 3 1 PH domain PH_11 PF15413.1 KFM01047.1 - 2.9e-07 30.7 6.2 6.4e-07 29.6 2.0 3.2 3 1 0 3 3 3 1 Pleckstrin homology domain PH_9 PF15410.1 KFM01047.1 - 0.0084 16.2 0.7 0.05 13.7 0.5 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 KFM01047.1 - 0.039 13.8 0.1 0.085 12.7 0.0 1.5 1 0 0 1 1 1 0 PH domain SpoIIAA-like PF11964.3 KFM01047.1 - 0.049 13.9 0.0 0.22 11.7 0.0 2.2 1 0 0 1 1 1 0 SpoIIAA-like Pentaxin PF00354.12 KFM01048.1 - 3.2e-30 105.0 0.0 6.2e-30 104.0 0.0 1.4 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.1 KFM01048.1 - 1.2e-14 54.8 0.0 1.8e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily SEO_C PF14577.1 KFM01048.1 - 0.021 14.1 1.1 0.051 12.9 0.3 2.0 1 1 1 2 2 2 0 Sieve element occlusion C-terminus DUF2001 PF09393.5 KFM01048.1 - 0.058 13.0 0.6 0.11 12.1 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2001) F-box-like_2 PF13013.1 KFM01049.1 - 0.13 12.0 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 F-box-like domain GAS PF13851.1 KFM01050.1 - 0.018 14.2 59.5 0.99 8.5 8.7 3.4 1 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 KFM01051.1 - 0.001 18.9 13.5 0.001 18.9 9.4 2.7 2 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WEMBL PF05701.6 KFM01051.1 - 0.0025 16.3 29.5 0.34 9.3 7.7 2.1 1 1 0 1 1 1 1 Weak chloroplast movement under blue light IFT57 PF10498.4 KFM01051.1 - 0.0041 15.9 27.0 0.016 13.9 5.9 2.2 2 0 0 2 2 2 2 Intra-flagellar transport protein 57 AAA_13 PF13166.1 KFM01051.1 - 0.022 13.2 24.9 0.0044 15.5 14.6 1.6 1 1 1 2 2 2 0 AAA domain IncA PF04156.9 KFM01051.1 - 0.053 13.1 36.7 0.2 11.2 9.4 2.7 1 1 2 3 3 3 0 IncA protein GAS PF13851.1 KFM01051.1 - 0.092 11.9 35.7 0.5 9.5 9.2 2.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.2 KFM01051.1 - 0.11 12.4 35.1 0.14 12.0 9.5 2.4 2 0 0 2 2 2 0 Tropomyosin like Spc7 PF08317.6 KFM01051.1 - 0.11 11.0 29.8 0.7 8.4 10.8 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein APG6 PF04111.7 KFM01051.1 - 0.14 11.1 32.5 0.036 13.1 8.9 2.1 1 1 0 2 2 2 0 Autophagy protein Apg6 DUF1515 PF07439.6 KFM01051.1 - 0.77 9.5 7.6 0.48 10.2 0.1 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF1515) NPV_P10 PF05531.7 KFM01051.1 - 0.88 9.8 13.7 27 5.1 0.3 4.2 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 KFM01051.1 - 0.89 8.6 7.4 2.5 7.2 0.3 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF1947 PF09183.5 KFM01051.1 - 1 9.1 4.3 2.3 8.0 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1947) Ku_C PF03730.9 KFM01051.1 - 1.2 9.7 16.3 0.058 13.9 2.7 3.4 2 2 2 4 4 4 0 Ku70/Ku80 C-terminal arm Syntaxin-6_N PF09177.6 KFM01051.1 - 2 8.8 17.3 7 7.1 2.6 3.6 1 1 2 3 3 3 0 Syntaxin 6, N-terminal DUF4559 PF15112.1 KFM01051.1 - 2.8 7.0 23.6 0.81 8.7 4.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) DUF972 PF06156.8 KFM01051.1 - 3.2 8.1 30.5 6 7.2 1.0 4.3 1 1 2 4 4 4 0 Protein of unknown function (DUF972) DUF3450 PF11932.3 KFM01051.1 - 6.2 6.0 21.7 1.1 8.4 2.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) UPF0449 PF15136.1 KFM01051.1 - 8 6.7 20.9 0.58 10.4 3.1 3.8 1 1 3 4 4 4 0 Uncharacterised protein family UPF0449 ADIP PF11559.3 KFM01051.1 - 8.2 6.3 31.9 1.4 8.7 4.3 3.4 2 2 1 3 3 3 0 Afadin- and alpha -actinin-Binding HSDR_N_2 PF13588.1 KFM01051.1 - 8.6 6.2 10.9 17 5.2 0.3 2.9 2 1 1 3 3 3 0 Type I restriction enzyme R protein N terminus (HSDR_N) F-box-like_2 PF13013.1 KFM01052.1 - 0.13 12.0 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 F-box-like domain PARP PF00644.15 KFM01053.1 - 4.3e-35 121.0 4.6 6.2e-34 117.2 3.2 1.9 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain TRAP-gamma PF07074.7 KFM01054.1 - 2.3e-69 232.2 6.4 2.6e-69 232.1 4.5 1.0 1 0 0 1 1 1 1 Translocon-associated protein, gamma subunit (TRAP-gamma) Kei1 PF08552.6 KFM01054.1 - 0.0064 16.1 2.4 0.0084 15.7 1.6 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 MatC_N PF07158.6 KFM01054.1 - 0.19 11.5 2.4 0.44 10.3 0.6 1.9 2 0 0 2 2 2 0 Dicarboxylate carrier protein MatC N-terminus SPC25 PF06703.6 KFM01054.1 - 0.24 10.9 3.1 0.15 11.6 1.0 1.6 1 1 1 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Aldo_ket_red PF00248.16 KFM01055.1 - 1.8e-15 56.5 0.0 2.2e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 KFM01056.1 - 3.1e-30 104.9 0.0 4.3e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family MRF_C2 PF13888.1 KFM01056.1 - 0.0053 16.5 0.0 0.008 15.9 0.0 1.2 1 0 0 1 1 1 1 Myelin gene regulatory factor C-terminal domain 2 GATase PF00117.23 KFM01057.1 - 1.6e-39 135.3 0.0 1.1e-38 132.5 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 KFM01057.1 - 3.8e-30 103.4 0.0 8.6e-30 102.3 0.0 1.7 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.12 KFM01057.1 - 3.8e-13 48.8 0.1 2.9e-09 36.2 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 KFM01057.1 - 8.1e-13 48.3 0.0 2e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Peptidase C26 QueC PF06508.8 KFM01057.1 - 3.3e-08 33.0 0.1 2.5e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 KFM01057.1 - 3.1e-06 26.8 0.0 5.4e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.11 KFM01057.1 - 3.4e-06 25.8 0.0 1.4e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 tRNA methyl transferase ATP_bind_3 PF01171.15 KFM01057.1 - 0.00047 19.7 0.0 0.00095 18.7 0.0 1.5 1 0 0 1 1 1 1 PP-loop family ThiI PF02568.9 KFM01057.1 - 0.00048 19.6 0.1 0.0011 18.4 0.0 1.7 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.14 KFM01057.1 - 0.00098 18.9 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Arginosuc_synth PF00764.14 KFM01057.1 - 0.0018 17.3 0.0 0.003 16.6 0.0 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase CW_binding_2 PF04122.7 KFM01057.1 - 0.019 15.1 0.0 0.11 12.6 0.0 2.4 2 0 0 2 2 2 0 Putative cell wall binding repeat 2 LytR_C PF13399.1 KFM01057.1 - 0.023 15.0 0.0 0.047 14.0 0.0 1.5 1 0 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator rve PF00665.21 KFM01057.1 - 0.032 14.3 0.0 0.069 13.2 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain Acatn PF13000.2 KFM01058.1 - 8.8e-99 331.4 17.4 2.6e-57 194.5 4.5 3.0 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 PI-PLC-X PF00388.14 KFM01059.1 - 1.3e-62 209.4 0.0 3e-62 208.3 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KFM01059.1 - 2.1e-42 143.8 0.4 6.6e-42 142.2 0.2 1.9 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 KFM01059.1 - 1.3e-24 86.0 3.7 1.6e-24 85.7 0.2 2.7 2 1 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 KFM01059.1 - 2.7e-16 59.1 0.0 6.8e-16 57.8 0.0 1.8 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.1 KFM01059.1 - 6.3e-12 45.4 1.8 9.7e-11 41.6 0.3 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KFM01059.1 - 2e-09 36.0 2.6 4e-05 22.6 0.0 3.6 3 1 0 3 3 3 2 EF hand EF-hand_10 PF14788.1 KFM01059.1 - 2.8e-07 30.1 4.3 4.1e-06 26.3 0.1 3.8 3 1 1 4 4 4 2 EF hand EF-hand_6 PF13405.1 KFM01059.1 - 7.3e-07 28.5 0.9 0.035 13.9 0.0 3.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 KFM01059.1 - 2.4e-05 23.4 4.8 0.00033 19.8 0.0 3.0 3 1 0 3 3 3 1 EF hand EF-hand_8 PF13833.1 KFM01059.1 - 8e-05 22.1 0.6 0.11 12.1 0.1 2.8 1 1 1 2 2 2 2 EF-hand domain pair PH PF00169.24 KFM01059.1 - 0.0047 17.1 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 PH domain SPARC_Ca_bdg PF10591.4 KFM01059.1 - 0.0047 16.9 2.3 0.005 16.8 0.1 2.1 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Mcp5_PH PF12814.2 KFM01059.1 - 0.014 15.2 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology EF-hand_4 PF12763.2 KFM01059.1 - 0.022 14.5 0.1 0.076 12.7 0.1 2.0 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Peptidase_M13_N PF05649.8 KFM01060.1 - 4e-133 444.2 2.4 4e-133 444.2 1.7 1.5 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13 PF01431.16 KFM01060.1 - 9.7e-64 214.3 0.0 2.4e-63 213.0 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_MA_2 PF13485.1 KFM01060.1 - 0.012 15.6 0.0 2.3 8.2 0.0 3.2 3 0 0 3 3 3 0 Peptidase MA superfamily DUF3317 PF11779.3 KFM01061.1 - 0.083 12.3 0.2 0.083 12.3 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3317) HA2 PF04408.18 KFM01062.1 - 1.4e-22 79.6 0.1 2.9e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KFM01062.1 - 6e-18 64.7 0.0 2.5e-17 62.7 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KFM01062.1 - 2.4e-13 49.7 0.1 5.1e-13 48.6 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFM01062.1 - 8.8e-13 48.0 0.3 6.5e-12 45.2 0.1 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KFM01062.1 - 2.8e-08 33.9 0.2 7.7e-08 32.5 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFM01062.1 - 0.0007 19.3 0.1 0.0022 17.6 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain KaiC PF06745.8 KFM01062.1 - 0.0025 16.9 0.0 0.0069 15.5 0.0 1.7 1 0 0 1 1 1 1 KaiC AAA_14 PF13173.1 KFM01062.1 - 0.0051 16.7 0.7 0.083 12.7 0.2 2.9 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 KFM01062.1 - 0.026 14.8 0.1 0.026 14.8 0.1 2.8 2 1 1 3 3 3 0 AAA domain AAA_16 PF13191.1 KFM01062.1 - 0.031 14.2 0.1 0.14 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain T2SE PF00437.15 KFM01062.1 - 0.075 11.9 0.0 0.18 10.6 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.11 KFM01062.1 - 0.089 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 KFM01062.1 - 0.12 12.0 0.3 0.65 9.6 0.2 2.4 1 1 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 KFM01062.1 - 0.33 11.2 2.0 0.86 9.8 0.1 2.5 2 1 1 3 3 3 0 ABC transporter RhoGEF PF00621.15 KFM01063.1 - 9.9e-38 129.8 8.3 2e-37 128.8 5.7 1.5 1 0 0 1 1 1 1 RhoGEF domain SH3_1 PF00018.23 KFM01063.1 - 4.5e-12 45.1 0.1 1.3e-11 43.6 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFM01063.1 - 3e-11 42.6 0.1 5.8e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFM01063.1 - 4.6e-10 38.8 0.0 1.3e-09 37.4 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain PH PF00169.24 KFM01063.1 - 1.1e-07 32.0 2.1 2.5e-07 30.8 0.1 2.4 2 1 0 2 2 2 1 PH domain NAGLU_C PF12972.2 KFM01063.1 - 0.013 14.9 0.3 0.028 13.7 0.2 1.5 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain Ras PF00071.17 KFM01064.1 - 7.1e-56 188.0 0.0 8.1e-56 187.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM01064.1 - 3.3e-21 76.0 0.2 5.3e-21 75.3 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFM01064.1 - 4.2e-10 39.1 0.0 4.7e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFM01064.1 - 2.3e-07 30.4 0.1 1.2e-06 28.1 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFM01064.1 - 0.00026 20.9 0.0 0.00037 20.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFM01064.1 - 0.0044 16.3 0.0 0.017 14.4 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B ArgK PF03308.11 KFM01064.1 - 0.016 13.9 0.1 0.29 9.8 0.0 2.1 2 0 0 2 2 2 0 ArgK protein DUF258 PF03193.11 KFM01064.1 - 0.11 11.7 0.8 0.66 9.1 0.3 2.1 2 1 0 2 2 2 0 Protein of unknown function, DUF258 7tm_1 PF00001.16 KFM01065.1 - 1.5e-47 161.8 20.6 2.4e-47 161.2 14.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TrbE PF11100.3 KFM01065.1 - 0.024 14.4 5.1 0.024 14.4 3.5 2.6 2 1 0 2 2 2 0 Conjugal transfer protein TrbE zf-CCCH PF00642.19 KFM01066.1 - 6.1e-10 38.5 25.4 0.00025 20.6 0.7 5.1 4 1 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1540 PF07561.6 KFM01066.1 - 0.91 9.6 5.3 23 5.1 0.1 3.6 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1540) 7tm_1 PF00001.16 KFM01067.1 - 3.9e-35 121.2 19.4 4.6e-35 120.9 13.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF1129 PF06570.6 KFM01067.1 - 0.72 9.1 10.1 0.27 10.5 4.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Abhydrolase_3 PF07859.8 KFM01068.1 - 6e-57 192.6 0.2 2.4e-40 138.3 0.0 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.23 KFM01068.1 - 5.3e-07 28.7 0.0 0.0005 18.9 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_5 PF12695.2 KFM01068.1 - 6.6e-05 22.7 0.0 0.00011 21.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFM01068.1 - 0.00023 20.4 0.0 0.00054 19.2 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.7 KFM01068.1 - 0.00064 18.3 0.0 0.0042 15.6 0.0 2.0 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.4 KFM01068.1 - 0.001 18.3 0.3 0.0028 16.9 0.0 1.8 2 0 0 2 2 2 1 Esterase PHB depolymerase DUF2424 PF10340.4 KFM01068.1 - 0.023 13.3 0.0 0.033 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Chlorophyllase2 PF12740.2 KFM01068.1 - 0.034 13.0 0.0 0.056 12.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Thioesterase PF00975.15 KFM01068.1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 Thioesterase domain zf-H2C2_2 PF13465.1 KFM01070.1 - 1.2e-35 120.0 61.8 1.3e-08 34.6 3.7 8.6 8 0 0 8 8 8 7 Zinc-finger double domain zf-C2H2 PF00096.21 KFM01070.1 - 2.4e-24 84.1 78.7 0.00033 20.7 3.4 8.7 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM01070.1 - 9.6e-16 56.8 63.1 0.00022 21.3 0.9 8.6 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM01070.1 - 2.6e-11 43.2 54.8 0.0016 18.4 0.9 8.6 9 0 0 9 9 9 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM01070.1 - 6.1e-08 32.6 54.3 0.016 15.4 0.3 8.5 8 0 0 8 8 8 4 Zinc-finger of C2H2 type zf-Di19 PF05605.7 KFM01070.1 - 7.1e-08 32.4 2.0 7.1e-08 32.4 1.4 4.5 4 1 0 4 4 4 1 Drought induced 19 protein (Di19), zinc-binding Homeobox PF00046.24 KFM01070.1 - 4.5e-05 22.9 0.0 0.00032 20.2 0.0 2.5 2 0 0 2 2 2 1 Homeobox domain zf-C2H2_6 PF13912.1 KFM01070.1 - 0.0046 16.8 61.7 0.0084 15.9 0.6 8.5 8 0 0 8 8 8 3 C2H2-type zinc finger DUF3524 PF12038.3 KFM01071.1 - 5.7e-66 221.2 0.1 1e-65 220.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3524) Glycos_transf_1 PF00534.15 KFM01071.1 - 6.7e-08 32.1 0.0 1.3e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KFM01071.1 - 3.7e-07 30.3 0.0 7.2e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 RhoGAP PF00620.22 KFM01072.1 - 1.3e-52 177.4 0.9 2.3e-51 173.4 0.0 2.6 2 1 0 2 2 2 1 RhoGAP domain RNA_binding PF01877.12 KFM01072.1 - 0.029 14.3 0.2 0.27 11.2 0.0 2.5 2 1 0 2 2 2 0 RNA binding Aminotran_5 PF00266.14 KFM01073.1 - 5.6e-15 54.9 0.0 7.1e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Ldl_recept_a PF00057.13 KFM01074.1 - 2.3e-281 907.3 599.3 7.5e-13 48.1 9.1 35.1 34 0 0 34 34 34 31 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.12 KFM01074.1 - 4.6e-179 580.5 86.7 1.8e-10 40.9 0.0 36.8 37 1 0 37 37 37 29 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.1 KFM01074.1 - 1.1e-70 233.4 354.5 2.2e-11 43.6 5.5 25.4 20 1 4 24 24 24 15 Coagulation Factor Xa inhibitory site SGL PF08450.7 KFM01074.1 - 1.9e-21 76.5 28.9 0.0031 16.9 0.2 15.3 10 5 5 16 16 16 5 SMP-30/Gluconolaconase/LRE-like region cEGF PF12662.2 KFM01074.1 - 1.1e-20 72.8 118.8 7.1e-08 31.9 0.2 17.0 15 0 0 15 15 15 8 Complement Clr-like EGF-like Arylesterase PF01731.15 KFM01074.1 - 0.00031 20.6 0.4 1.4e+02 2.5 0.0 8.6 10 2 1 11 11 11 0 Arylesterase TMEM154 PF15102.1 KFM01074.1 - 0.066 12.9 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family Enterotoxin_a PF01375.12 KFM01075.1 - 0.14 11.4 0.0 0.65 9.2 0.0 1.8 2 0 0 2 2 2 0 Heat-labile enterotoxin alpha chain EGF PF00008.22 KFM01076.1 - 2.5e-07 30.5 22.2 1.7e-05 24.6 6.0 4.2 4 0 0 4 4 4 2 EGF-like domain EGF_2 PF07974.8 KFM01077.1 - 3.5e-17 62.2 44.0 6.2e-07 29.4 6.8 3.2 3 0 0 3 3 3 3 EGF-like domain EGF PF00008.22 KFM01077.1 - 2e-13 50.0 41.4 1.6e-05 24.7 5.5 3.5 3 1 0 3 3 3 3 EGF-like domain hEGF PF12661.2 KFM01077.1 - 6.2e-07 29.0 40.0 0.0011 18.9 2.4 5.1 5 0 0 5 5 5 3 Human growth factor-like EGF Laminin_EGF PF00053.19 KFM01077.1 - 0.0026 17.6 38.1 0.94 9.4 5.5 3.1 1 1 2 3 3 3 3 Laminin EGF-like (Domains III and V) Neurexophilin PF06312.7 KFM01078.1 - 2.8e-110 366.7 4.9 3e-110 366.6 3.4 1.0 1 0 0 1 1 1 1 Neurexophilin Nepo_coat_C PF03688.9 KFM01078.1 - 0.061 12.9 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Nepovirus coat protein, C-terminal domain BTB PF00651.26 KFM01079.1 - 7.5e-35 119.2 0.9 8.4e-34 115.9 0.1 2.2 1 1 1 2 2 2 1 BTB/POZ domain MATH PF00917.21 KFM01079.1 - 1.1e-09 38.5 0.3 3e-09 37.1 0.0 1.8 2 0 0 2 2 2 1 MATH domain BTB_2 PF02214.17 KFM01079.1 - 0.00063 19.8 0.1 0.0018 18.4 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.10 KFM01079.1 - 0.15 11.9 1.6 12 5.8 0.0 3.5 4 0 0 4 4 4 0 BTB And C-terminal Kelch Methyltransf_23 PF13489.1 KFM01080.1 - 3.3e-15 56.1 0.0 4.9e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFM01080.1 - 1.7e-08 34.8 0.0 2.8e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFM01080.1 - 0.0004 19.9 0.0 0.0006 19.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain WIF PF02019.13 KFM01080.1 - 0.016 14.6 0.2 0.05 13.0 0.1 1.9 2 0 0 2 2 2 0 WIF domain Methyltransf_11 PF08241.7 KFM01080.1 - 0.065 13.7 0.0 0.14 12.6 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain TSP_1 PF00090.14 KFM01081.1 - 1.2e-37 127.7 215.8 2.6e-09 37.0 4.8 22.9 23 2 0 23 23 23 14 Thrombospondin type 1 domain 7tm_1 PF00001.16 KFM01082.1 - 2.8e-57 193.7 14.8 3.4e-57 193.5 10.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CXCR4_N PF12109.3 KFM01082.1 - 2.2e-19 68.9 5.7 3.5e-19 68.2 3.9 1.3 1 0 0 1 1 1 1 CXCR4 Chemokine receptor N terminal 7TM_GPCR_Srsx PF10320.4 KFM01082.1 - 0.0023 17.1 14.6 0.0035 16.5 10.1 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.1 KFM01082.1 - 0.014 15.1 3.2 0.014 15.1 2.2 2.7 1 1 1 2 2 2 0 Olfactory receptor CitMHS PF03600.11 KFM01082.1 - 1.1 7.7 8.1 0.37 9.3 0.8 2.1 2 0 0 2 2 2 0 Citrate transporter tRNA-synt_2 PF00152.15 KFM01083.1 - 1.8e-80 270.2 0.1 2.4e-80 269.8 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KFM01083.1 - 2e-09 37.1 0.8 3.4e-09 36.4 0.6 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KFM01083.1 - 1.5e-05 24.3 0.4 0.13 11.4 0.2 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) S-AdoMet_synt_N PF00438.15 KFM01083.1 - 0.0015 18.6 0.2 0.0092 16.1 0.2 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain Glyco_hydro_1 PF00232.13 KFM01084.1 - 4.1e-176 585.6 0.8 4.6e-176 585.4 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_1 PF00232.13 KFM01085.1 - 1.6e-81 273.8 0.4 1.8e-81 273.6 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 UBX PF00789.15 KFM01086.1 - 2e-18 66.2 0.1 6.1e-18 64.6 0.0 1.9 2 0 0 2 2 2 1 UBX domain Ycf1 PF05758.7 KFM01086.1 - 5.9 4.4 13.8 7.6 4.0 9.5 1.2 1 0 0 1 1 1 0 Ycf1 R3H PF01424.17 KFM01087.1 - 1.7e-13 50.0 0.0 3.7e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 R3H domain SUZ PF12752.2 KFM01087.1 - 4.9e-11 42.9 6.8 4.9e-11 42.9 4.7 3.7 3 0 0 3 3 3 1 SUZ domain Transposase_20 PF02371.11 KFM01087.1 - 0.29 11.2 1.5 7.7 6.6 0.0 2.5 2 0 0 2 2 2 0 Transposase IS116/IS110/IS902 family SNF2_N PF00176.18 KFM01088.1 - 4e-37 127.6 0.0 7.1e-37 126.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFM01088.1 - 2.2e-11 43.4 0.0 7.2e-11 41.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HNH PF01844.18 KFM01088.1 - 3e-09 36.6 1.9 6.3e-09 35.5 0.0 2.6 2 0 0 2 2 2 1 HNH endonuclease Flavi_DEAD PF07652.9 KFM01088.1 - 0.025 14.3 0.0 0.062 13.0 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain zf-RanBP PF00641.13 KFM01088.1 - 0.22 10.6 13.6 0.017 14.2 5.2 2.4 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Rab3-GTPase_cat PF13890.1 KFM01089.1 - 9.2e-68 226.7 0.0 7e-67 223.9 0.0 2.2 2 0 0 2 2 2 1 Rab3 GTPase-activating protein catalytic subunit Pkinase PF00069.20 KFM01090.1 - 1.9e-56 191.1 0.0 2.1e-56 190.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM01090.1 - 2.9e-38 131.4 0.0 3.4e-38 131.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM01090.1 - 9.8e-07 28.0 0.0 1.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFM01090.1 - 0.0012 18.6 0.0 0.0037 17.0 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KFM01090.1 - 0.091 11.5 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Cyclin_N PF00134.18 KFM01091.1 - 4.5e-16 58.5 1.3 7.3e-13 48.1 0.1 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFM01091.1 - 1.2 9.0 14.8 0.36 10.7 0.1 3.7 4 0 0 4 4 4 0 Cyclin, C-terminal domain Amidohydro_2 PF04909.9 KFM01092.1 - 1.6e-52 178.8 0.0 1.8e-52 178.5 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase Cation_efflux PF01545.16 KFM01093.1 - 0.0024 16.9 26.7 0.0075 15.3 18.5 1.7 1 1 0 1 1 1 1 Cation efflux family Orbi_NS3 PF01616.11 KFM01093.1 - 0.064 12.2 1.7 4.3 6.2 0.3 2.3 2 0 0 2 2 2 0 Orbivirus NS3 DUF1385 PF07136.6 KFM01093.1 - 0.2 10.6 4.4 3 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1385) DUF3040 PF11239.3 KFM01093.1 - 0.42 10.7 11.6 2.2 8.3 0.6 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF3040) DUF308 PF03729.8 KFM01093.1 - 5.8 6.9 18.3 7.9 6.5 5.3 3.2 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) Glyco_transf_18 PF15024.1 KFM01094.1 - 6.3e-255 846.8 0.6 8.1e-255 846.4 0.4 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 18 DUF4525 PF15027.1 KFM01094.1 - 3.5e-68 227.4 0.2 6.2e-68 226.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4525) DUF3049 PF11250.3 KFM01095.1 - 0.15 11.8 0.8 1.3 8.8 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3049) NCKAP5 PF15246.1 KFM01098.1 - 7.8e-119 396.7 24.3 7.8e-119 396.7 16.9 4.1 4 0 0 4 4 4 1 Nck-associated protein 5, Peripheral clock protein 7tm_1 PF00001.16 KFM01100.1 - 2.2e-34 118.7 9.3 2.2e-34 118.7 6.4 2.0 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 KFM01100.1 - 2.6e-05 23.5 1.2 2.6e-05 23.5 0.9 2.5 2 1 1 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srv EamA PF00892.15 KFM01101.1 - 1.1e-10 41.5 35.3 4.8e-07 29.8 3.2 3.3 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 KFM01101.1 - 0.0012 19.0 3.5 0.0012 19.0 2.4 3.7 3 2 1 4 4 4 1 Multidrug resistance efflux transporter DUF2637 PF10935.3 KFM01101.1 - 0.053 13.4 0.2 0.19 11.6 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2637) DUF3087 PF11286.3 KFM01101.1 - 0.39 9.9 1.8 0.85 8.8 0.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3087) Cytochrom_B_C PF00032.12 KFM01101.1 - 5.9 7.1 19.8 0.3 11.3 0.3 4.3 3 1 1 4 4 4 0 Cytochrome b(C-terminal)/b6/petD V-set PF07686.12 KFM01102.1 - 7.7e-13 48.3 0.0 8.7e-13 48.1 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 KFM01102.1 - 0.11 12.6 0.1 0.18 11.9 0.1 1.7 1 1 0 1 1 1 0 Immunoglobulin domain 7tm_4 PF13853.1 KFM01103.1 - 1.2e-55 187.2 4.7 1.2e-55 187.2 3.3 1.5 1 1 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.16 KFM01103.1 - 9.1e-13 47.9 10.3 1.8e-08 33.8 0.9 2.2 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) HlyIII PF03006.15 KFM01103.1 - 0.013 14.9 1.7 0.013 14.9 1.2 2.2 2 1 0 2 2 2 0 Haemolysin-III related DUF202 PF02656.10 KFM01103.1 - 4.3 7.6 5.4 0.84 9.8 0.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF202) 7tm_4 PF13853.1 KFM01104.1 - 2.2e-40 137.7 20.7 2.2e-40 137.7 14.3 2.3 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFM01104.1 - 3e-29 101.9 26.8 3.8e-29 101.6 18.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2868 PF11067.3 KFM01104.1 - 0.041 13.0 1.4 0.075 12.1 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) 7tm_4 PF13853.1 KFM01105.1 - 2.8e-38 130.9 13.5 2.8e-38 130.9 9.3 3.1 2 1 1 3 3 3 1 Olfactory receptor 7tm_1 PF00001.16 KFM01105.1 - 5.4e-31 107.6 20.4 7.1e-31 107.2 14.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM01105.1 - 0.00015 21.0 23.7 0.00038 19.7 16.4 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.1 KFM01106.1 - 2e-41 141.1 19.3 2e-41 141.1 13.4 2.2 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFM01106.1 - 1.5e-29 102.9 24.5 2e-29 102.5 17.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 KFM01107.1 - 3.2e-43 146.9 12.9 3.2e-43 146.9 9.0 2.3 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFM01107.1 - 6.6e-30 104.1 23.5 9.4e-30 103.5 16.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) FYRN PF05964.9 KFM01108.1 - 1.8e-22 78.5 0.1 3.3e-22 77.6 0.1 1.5 1 0 0 1 1 1 1 F/Y-rich N-terminus zf-HC5HC2H PF13771.1 KFM01108.1 - 2.4e-14 53.2 6.4 2.4e-14 53.2 4.5 3.0 3 0 0 3 3 3 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 KFM01108.1 - 3.7e-10 39.7 8.6 3.7e-10 39.7 6.0 2.0 2 0 0 2 2 2 1 PHD-zinc-finger like domain PRCC PF10253.4 KFM01109.1 - 2.1e-27 96.9 29.0 7.9e-25 88.6 18.2 2.7 2 1 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting TEBP_beta PF07404.6 KFM01109.1 - 0.044 12.9 4.1 0.075 12.1 2.9 1.3 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) SH2 PF00017.19 KFM01110.1 - 5.4e-18 64.5 0.0 7.4e-18 64.1 0.0 1.2 1 0 0 1 1 1 1 SH2 domain Pkinase_Tyr PF07714.12 KFM01111.1 - 7.6e-53 179.2 0.0 1e-52 178.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM01111.1 - 2.9e-28 98.7 0.0 4.1e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain I-set PF07679.11 KFM01111.1 - 2.8e-06 27.0 0.0 0.0025 17.6 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.20 KFM01111.1 - 0.021 14.9 0.1 0.62 10.2 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin domain Ig_2 PF13895.1 KFM01111.1 - 0.035 14.2 0.1 0.31 11.1 0.0 2.5 2 1 1 3 3 3 0 Immunoglobulin domain C2-set_2 PF08205.7 KFM01111.1 - 0.11 12.3 0.0 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain FYVE PF01363.16 KFM01113.1 - 3.7e-16 58.7 18.8 1.7e-15 56.6 13.1 2.2 1 0 0 1 1 1 1 FYVE zinc finger RUN PF02759.14 KFM01113.1 - 1.2e-08 34.8 0.0 1.2e-08 34.8 0.0 5.4 4 2 0 4 4 4 1 RUN domain GOLD_2 PF13897.1 KFM01113.1 - 2.4e-05 24.5 0.1 2.4e-05 24.5 0.0 6.6 5 2 4 9 9 9 1 Golgi-dynamics membrane-trafficking Reo_sigmaC PF04582.7 KFM01113.1 - 8 5.5 77.4 0.044 12.9 2.3 8.6 3 2 3 8 8 8 0 Reovirus sigma C capsid protein 7tm_1 PF00001.16 KFM01114.1 - 1.5e-55 188.1 22.5 2.1e-55 187.6 15.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM01114.1 - 0.00036 19.7 23.4 0.00051 19.2 16.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.16 KFM01115.1 - 5.3e-58 196.1 20.5 6.3e-58 195.9 14.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM01115.1 - 1e-09 37.9 22.9 1.3e-09 37.6 15.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.1 KFM01115.1 - 0.011 15.5 7.9 0.011 15.5 5.5 2.7 1 1 1 2 2 2 0 Olfactory receptor 7tm_1 PF00001.16 KFM01116.1 - 3.6e-56 190.1 19.0 4.4e-56 189.8 13.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM01116.1 - 1e-09 37.9 20.5 1.4e-09 37.5 14.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.1 KFM01116.1 - 0.0044 16.8 6.8 0.0044 16.8 4.7 2.8 1 1 1 2 2 2 1 Olfactory receptor BRCT PF00533.21 KFM01117.1 - 2e-43 146.3 0.9 3.8e-17 62.2 0.1 4.2 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KFM01117.1 - 7.3e-41 137.8 3.9 2.3e-23 81.8 0.5 3.8 4 0 0 4 4 4 3 twin BRCT domain CDV3 PF15359.1 KFM01119.1 - 1.2e-61 206.4 6.5 1.6e-61 206.0 4.5 1.2 1 0 0 1 1 1 1 Carnitine deficiency-associated protein 3 Filament PF00038.16 KFM01120.1 - 3.5e-53 181.1 28.0 4.2e-53 180.8 19.4 1.0 1 0 0 1 1 1 1 Intermediate filament protein Dimer_Tnp_Tn5 PF02281.11 KFM01120.1 - 0.038 14.0 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 Transposase Tn5 dimerisation domain Lectin_N PF03954.9 KFM01120.1 - 0.047 13.0 4.4 0.048 13.0 0.9 2.4 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain T2SF PF00482.18 KFM01120.1 - 2.3 8.1 5.8 1.7 8.5 0.1 3.2 3 2 1 4 4 4 0 Type II secretion system (T2SS), protein F PhoU PF01895.14 KFM01120.1 - 9.7 6.7 9.5 3.6 8.1 1.4 3.2 1 1 3 4 4 4 0 PhoU domain TPR_12 PF13424.1 KFM01121.1 - 1.4e-100 329.3 38.1 1e-20 73.4 1.7 6.6 2 2 5 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.1 KFM01121.1 - 3.1e-66 217.5 23.7 9.8e-12 44.3 0.3 9.7 10 0 0 10 10 9 8 Tetratricopeptide repeat TPR_11 PF13414.1 KFM01121.1 - 1.7e-32 110.8 21.6 4e-11 42.3 1.6 6.1 4 1 2 6 6 6 6 TPR repeat TPR_1 PF00515.23 KFM01121.1 - 1.5e-31 106.6 34.3 5.8e-06 25.6 1.9 9.1 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_7 PF13176.1 KFM01121.1 - 1.5e-28 96.3 26.9 0.00024 20.6 0.1 10.0 10 0 0 10 10 9 7 Tetratricopeptide repeat TPR_2 PF07719.12 KFM01121.1 - 4.5e-19 66.7 35.8 0.0033 17.2 0.1 9.1 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_16 PF13432.1 KFM01121.1 - 5.7e-15 55.5 21.2 0.00029 21.3 0.0 7.2 5 1 2 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFM01121.1 - 3.3e-13 48.7 12.2 0.026 14.7 0.1 8.8 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFM01121.1 - 5.8e-11 41.3 42.3 0.00059 19.4 1.9 10.1 11 0 0 11 11 9 4 Tetratricopeptide repeat TPR_14 PF13428.1 KFM01121.1 - 1e-10 41.2 19.4 0.69 10.7 0.6 9.3 5 2 4 9 9 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFM01121.1 - 2.6e-09 37.2 21.0 0.0045 17.3 0.1 5.6 4 1 1 5 5 5 3 Tetratricopeptide repeat NACHT PF05729.7 KFM01121.1 - 1.9e-07 30.8 0.2 8.7e-07 28.7 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KFM01121.1 - 1.7e-05 24.9 0.0 0.00013 22.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFM01121.1 - 3.6e-05 23.8 3.6 3.8e-05 23.7 0.1 3.0 2 1 0 2 2 1 1 AAA ATPase domain TPR_3 PF07720.7 KFM01121.1 - 0.00044 19.9 22.0 2.1 8.2 0.6 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat KAP_NTPase PF07693.9 KFM01121.1 - 0.0016 17.5 0.0 0.31 9.9 0.0 3.0 2 1 1 3 3 3 1 KAP family P-loop domain TPR_6 PF13174.1 KFM01121.1 - 0.0027 18.0 24.0 2.6 8.6 0.1 7.9 9 0 0 9 9 6 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 KFM01121.1 - 0.044 13.0 9.1 1.8 7.9 0.1 6.0 7 0 0 7 7 7 0 SHNi-TPR AAA_19 PF13245.1 KFM01121.1 - 0.073 12.8 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA PF00004.24 KFM01121.1 - 0.11 12.6 0.0 0.43 10.7 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Pox_H7 PF04787.7 KFM01121.1 - 0.14 11.9 5.1 5.4 6.8 0.0 3.8 3 1 0 3 3 3 0 Late protein H7 DUF4404 PF14357.1 KFM01121.1 - 0.44 10.9 14.9 4 7.9 0.0 6.6 4 4 3 7 7 7 0 Domain of unknown function (DUF4404) Spc24 PF08286.6 KFM01121.1 - 4.3 7.0 12.9 10 5.8 3.8 2.9 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 IncA PF04156.9 KFM01121.1 - 6.1 6.4 18.8 0.24 10.9 8.1 2.3 2 0 0 2 2 2 0 IncA protein ThiF PF00899.16 KFM01122.1 - 7.4e-36 122.9 0.0 1.6e-35 121.8 0.0 1.6 1 0 0 1 1 1 1 ThiF family UDPG_MGDP_dh_N PF03721.9 KFM01122.1 - 0.0065 15.8 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain MoeZ_MoeB PF05237.8 KFM01122.1 - 0.028 14.0 0.4 0.082 12.5 0.1 2.0 2 0 0 2 2 2 0 MoeZ/MoeB domain NAD_binding_7 PF13241.1 KFM01122.1 - 0.037 14.2 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 KFM01122.1 - 0.048 12.8 0.2 0.17 11.0 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Adaptin_binding PF10199.4 KFM01122.1 - 0.12 12.6 2.7 0.31 11.3 1.9 1.7 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 7tm_1 PF00001.16 KFM01123.1 - 4.9e-51 173.3 18.6 6.7e-51 172.8 12.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM01123.1 - 6.1e-08 32.1 16.3 6.1e-08 32.1 11.3 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF202 PF02656.10 KFM01123.1 - 0.08 13.1 2.1 2.8 8.2 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF202) 7tm_4 PF13853.1 KFM01123.1 - 5.2 6.8 18.9 0.32 10.7 6.2 3.0 2 2 1 3 3 3 0 Olfactory receptor DnaJ PF00226.26 KFM01124.1 - 6.4e-16 57.8 0.3 6.4e-16 57.8 0.2 1.9 2 0 0 2 2 2 1 DnaJ domain DUF4339 PF14237.1 KFM01124.1 - 6.5e-13 48.0 0.9 2e-12 46.4 0.6 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4339) INTS5_N PF14837.1 KFM01124.1 - 0.02 14.3 0.4 0.068 12.5 0.3 2.0 1 0 0 1 1 1 0 Integrator complex subunit 5 N-terminus GYF PF02213.11 KFM01124.1 - 0.064 12.8 1.0 0.16 11.5 0.7 1.7 1 0 0 1 1 1 0 GYF domain His_Phos_2 PF00328.17 KFM01125.1 - 2e-60 204.9 0.2 2.7e-60 204.5 0.2 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 KFM01125.1 - 0.00082 19.4 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Copine PF07002.11 KFM01127.1 - 1.7e-64 215.9 0.1 3.5e-64 214.9 0.0 1.6 1 0 0 1 1 1 1 Copine C2 PF00168.25 KFM01127.1 - 2.6e-25 88.0 0.2 4e-13 49.0 0.1 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.4 KFM01127.1 - 6.9e-09 35.8 0.0 1.3e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.23 KFM01127.1 - 0.0014 18.4 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Ribosomal_L3 PF00297.17 KFM01128.1 - 6.1e-41 140.5 4.3 2.7e-37 128.6 1.9 2.1 1 1 1 2 2 2 2 Ribosomal protein L3 Pkinase PF00069.20 KFM01129.1 - 2.3e-67 226.9 0.3 5.4e-67 225.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM01129.1 - 1.8e-48 164.8 0.0 4.2e-48 163.6 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFM01129.1 - 0.041 13.6 0.1 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family E1-E2_ATPase PF00122.15 KFM01131.1 - 1.5e-73 246.6 1.4 3.4e-73 245.4 0.2 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFM01131.1 - 8.8e-43 145.9 4.3 8.8e-43 145.9 3.0 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFM01131.1 - 3.9e-30 105.8 0.2 2.2e-29 103.4 0.2 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFM01131.1 - 4.4e-18 65.0 0.1 1.6e-17 63.1 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KFM01131.1 - 7e-14 52.4 0.0 1.3e-13 51.5 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFM01131.1 - 8.4e-13 47.5 0.0 2.2e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KFM01131.1 - 0.00032 20.3 2.9 0.00032 20.3 2.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.20 KFM01133.1 - 5.1e-23 81.5 0.0 1.7e-22 79.7 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain WD40 PF00400.27 KFM01133.1 - 6.6e-19 67.0 12.5 7.7e-08 31.9 0.2 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat HEAT PF02985.17 KFM01133.1 - 1.6e-11 43.2 1.1 0.043 13.9 0.0 6.1 6 0 0 6 6 6 3 HEAT repeat Pkinase_Tyr PF07714.12 KFM01133.1 - 2.3e-07 30.1 0.0 1.2e-06 27.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 KFM01133.1 - 0.00054 20.1 0.4 0.31 11.3 0.1 3.6 2 1 0 3 3 3 1 HEAT repeats ELL PF10390.4 KFM01134.1 - 6.5e-88 294.6 0.3 6.5e-88 294.6 0.2 2.0 2 0 0 2 2 2 1 RNA polymerase II elongation factor ELL Occludin_ELL PF07303.8 KFM01134.1 - 1.1e-32 112.7 9.4 1.1e-32 112.7 6.5 3.0 3 0 0 3 3 3 1 Occludin homology domain Peptidase_S8 PF00082.17 KFM01135.1 - 8.6e-60 202.2 3.2 1.4e-59 201.6 2.2 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 KFM01135.1 - 1.4e-30 104.9 0.4 2.5e-30 104.0 0.3 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain Proho_convert PF12177.3 KFM01135.1 - 7.8e-25 86.1 2.5 3.3e-24 84.1 1.4 2.4 2 0 0 2 2 2 1 Prohormone convertase enzyme DUF3376 PF11856.3 KFM01135.1 - 0.044 13.1 0.1 0.07 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3376) Calpain_inhib PF00748.14 KFM01136.1 - 1.1e-141 465.8 91.6 1.5e-42 145.0 11.4 6.2 5 1 1 6 6 6 5 Calpain inhibitor Peptidase_M1 PF01433.15 KFM01137.1 - 1.2e-120 403.1 0.4 1.9e-120 402.5 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 KFM01137.1 - 2.3e-50 171.7 1.0 4.1e-50 170.8 0.7 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KFM01137.1 - 1.4e-17 63.9 0.1 3.1e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily DUF659 PF04937.10 KFM01137.1 - 0.0011 18.5 0.7 0.0093 15.4 0.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Peptidase_M30 PF10460.4 KFM01137.1 - 0.016 14.0 0.1 0.029 13.2 0.1 1.3 1 0 0 1 1 1 0 Peptidase M30 BLOC1_2 PF10046.4 KFM01137.1 - 0.025 14.7 0.6 0.08 13.0 0.1 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 tRNA_m1G_MT PF01746.16 KFM01138.1 - 3.4e-25 88.7 0.0 3.8e-25 88.5 0.0 1.0 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase WD40 PF00400.27 KFM01139.1 - 6.2e-21 73.4 10.3 2e-06 27.4 0.4 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat Mito_carr PF00153.22 KFM01140.1 - 1.5e-36 123.9 0.2 2.6e-11 43.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Beta_helix PF13229.1 KFM01141.1 - 1.2e-49 168.0 70.6 7.9e-18 64.6 6.6 5.2 3 2 2 5 5 5 5 Right handed beta helix region NosD PF05048.8 KFM01141.1 - 2.3e-33 115.3 30.0 7.2e-12 44.9 6.6 4.6 3 2 2 5 5 5 4 Periplasmic copper-binding protein (NosD) F-box-like PF12937.2 KFM01141.1 - 7.8e-11 41.5 3.3 1.7e-10 40.4 2.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFM01141.1 - 2.4e-08 33.4 1.4 6e-08 32.1 1.0 1.8 1 0 0 1 1 1 1 F-box domain ImcF-related_N PF14331.1 KFM01141.1 - 0.027 13.3 1.0 0.056 12.3 0.7 1.4 1 0 0 1 1 1 0 ImcF-related N-terminal domain Pentapeptide_4 PF13599.1 KFM01141.1 - 1.2 9.0 6.0 6.3 6.6 3.0 2.6 2 1 0 2 2 2 0 Pentapeptide repeats (9 copies) BTB PF00651.26 KFM01142.1 - 3e-29 101.2 1.1 6.8e-29 100.0 0.7 1.7 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 KFM01142.1 - 2.3e-07 30.7 2.8 2.3e-07 30.7 2.0 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM01142.1 - 3.2e-05 23.9 11.9 0.049 13.9 2.6 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KFM01142.1 - 0.002 18.3 5.1 0.002 18.3 3.5 3.3 2 0 0 2 2 2 1 Zinc finger, C2H2 type DUF3342 PF11822.3 KFM01142.1 - 0.013 14.6 0.2 0.013 14.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) APP_N PF02177.11 KFM01142.1 - 0.014 15.3 0.5 0.033 14.0 0.3 1.6 1 0 0 1 1 1 0 Amyloid A4 N-terminal heparin-binding Rota_NS35 PF02509.9 KFM01142.1 - 0.037 12.7 0.1 0.063 11.9 0.1 1.3 1 0 0 1 1 1 0 Rotavirus non-structural protein 35 2-Hacid_dh_C PF02826.14 KFM01143.1 - 1.8e-59 199.8 0.0 2.3e-59 199.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFM01143.1 - 9e-19 67.2 0.0 1e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.12 KFM01143.1 - 7.5e-07 29.5 0.0 1.8e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 KFM01143.1 - 6.5e-06 26.0 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.16 KFM01143.1 - 0.012 15.4 0.1 0.064 13.0 0.0 2.1 3 0 0 3 3 3 0 ThiF family IlvN PF07991.7 KFM01143.1 - 0.037 13.4 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 KFM01143.1 - 0.049 13.6 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.15 KFM01143.1 - 0.073 13.1 0.0 0.16 12.0 0.0 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase zf-CCHC PF00098.18 KFM01144.1 - 8.8e-09 34.8 43.1 1.5e-05 24.6 0.4 5.4 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_3 PF13917.1 KFM01144.1 - 7.4e-05 22.4 4.5 0.0014 18.2 0.4 5.0 2 1 3 5 5 5 3 Zinc knuckle RIG-I_C-RD PF11648.3 KFM01144.1 - 0.049 13.4 1.7 0.35 10.7 0.3 2.2 2 0 0 2 2 2 0 C-terminal domain of RIG-I PAX PF00292.13 KFM01146.1 - 2.5e-73 243.6 0.7 4e-73 243.0 0.5 1.3 1 0 0 1 1 1 1 'Paired box' domain Pax2_C PF12403.3 KFM01146.1 - 3e-42 142.9 7.1 3e-42 142.9 4.9 2.0 2 0 0 2 2 2 1 Paired-box protein 2 C terminal HTH_29 PF13551.1 KFM01146.1 - 6.3e-05 23.0 0.0 0.0001 22.4 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 KFM01146.1 - 9.1e-05 21.9 0.0 0.00018 21.0 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.1 KFM01146.1 - 0.0057 17.4 0.1 0.13 13.0 0.0 2.4 1 1 1 2 2 2 1 Homeodomain-like domain HTH_Tnp_IS1 PF12759.2 KFM01146.1 - 0.017 14.5 0.3 0.078 12.4 0.0 2.0 2 0 0 2 2 2 0 InsA C-terminal domain Ribosomal_S13_N PF08069.7 KFM01146.1 - 0.049 13.4 0.1 0.22 11.3 0.0 2.0 2 0 0 2 2 2 0 Ribosomal S13/S15 N-terminal domain Homeobox PF00046.24 KFM01146.1 - 0.081 12.5 0.1 0.2 11.3 0.1 1.6 1 0 0 1 1 1 0 Homeobox domain Pkinase PF00069.20 KFM01147.1 - 2.6e-75 252.9 0.1 7.4e-75 251.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM01147.1 - 9.7e-40 136.2 0.0 1.7e-39 135.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 KFM01147.1 - 5.5e-16 57.7 0.1 1.1e-15 56.8 0.1 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.1 KFM01147.1 - 1.8e-07 30.4 0.0 4.3e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFM01147.1 - 1.5e-05 24.1 0.0 2.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFM01147.1 - 0.00014 21.7 0.0 0.017 14.8 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFM01147.1 - 0.0073 15.8 0.3 0.037 13.6 0.0 2.2 2 1 0 2 2 2 1 Choline/ethanolamine kinase AMOP PF03782.12 KFM01148.1 - 4.4e-52 176.1 8.6 8.3e-52 175.2 5.9 1.5 1 0 0 1 1 1 1 AMOP domain VWD PF00094.20 KFM01148.1 - 5.8e-14 52.5 0.1 1.4e-13 51.3 0.1 1.7 1 0 0 1 1 1 1 von Willebrand factor type D domain Sushi PF00084.15 KFM01148.1 - 7.4e-09 35.8 0.6 3.4e-08 33.7 0.4 2.2 1 0 0 1 1 1 1 Sushi domain (SCR repeat) Somatomedin_B PF01033.12 KFM01148.1 - 2.4e-08 33.8 10.3 2.4e-08 33.8 7.1 2.2 2 0 0 2 2 2 1 Somatomedin B domain RGM_N PF06535.7 KFM01148.1 - 0.0061 16.5 0.1 0.018 15.0 0.1 1.8 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) N-terminus PP2C PF00481.16 KFM01149.1 - 5.2e-65 219.3 0.0 6.5e-65 219.0 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KFM01149.1 - 0.0028 17.0 0.0 0.011 15.1 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C HHH_5 PF14520.1 KFM01149.1 - 0.015 15.4 0.0 0.033 14.3 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain Topoisom_bac PF01131.15 KFM01150.1 - 2e-104 349.6 0.0 2.5e-104 349.3 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 KFM01150.1 - 8.3e-14 51.3 0.0 1.7e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Toprim domain DUF3628 PF12300.3 KFM01150.1 - 0.053 13.5 1.3 0.096 12.7 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) Fer4_11 PF13247.1 KFM01150.1 - 1.4 8.8 11.4 0.15 11.9 4.4 2.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain MIR PF02815.14 KFM01151.1 - 2.2e-13 50.1 0.0 1.6e-10 40.8 0.0 2.0 1 1 1 2 2 2 2 MIR domain RicinB_lectin_2 PF14200.1 KFM01151.1 - 0.061 13.7 0.3 1.1 9.6 0.1 2.6 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Ins145_P3_rec PF08709.6 KFM01151.1 - 0.13 11.2 0.0 0.3 10.0 0.0 1.5 2 0 0 2 2 2 0 Inositol 1,4,5-trisphosphate/ryanodine receptor YdjC PF04794.7 KFM01152.1 - 2.8e-36 125.3 0.0 3.2e-36 125.1 0.0 1.0 1 0 0 1 1 1 1 YdjC-like protein UQ_con PF00179.21 KFM01153.1 - 8.5e-43 145.1 0.3 9.5e-43 144.9 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFM01153.1 - 2.1e-07 30.7 0.0 2.7e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 KFM01153.1 - 5.3e-05 22.8 0.1 9.2e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 KFM01153.1 - 0.00014 21.7 0.6 0.00017 21.4 0.4 1.6 1 1 0 1 1 1 1 RWD domain BTB PF00651.26 KFM01154.1 - 7e-27 93.6 0.2 1.1e-26 92.9 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.21 KFM01154.1 - 2.6e-25 87.2 24.7 9e-06 25.7 0.8 5.9 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM01154.1 - 4.7e-22 76.6 21.0 1.7e-05 24.7 0.2 5.7 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFM01154.1 - 1.9e-21 75.2 29.5 2.5e-08 33.7 0.2 7.6 6 1 0 6 6 6 4 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFM01154.1 - 3.9e-18 65.0 4.5 0.00032 20.7 0.2 5.9 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM01154.1 - 6.4e-12 45.2 14.1 0.0028 17.7 0.3 5.9 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFM01154.1 - 5.3e-10 38.8 12.1 0.06 13.2 0.1 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-Di19 PF05605.7 KFM01154.1 - 0.00082 19.4 11.5 0.13 12.3 0.4 3.8 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 KFM01154.1 - 0.0017 18.3 14.8 5.6 7.1 0.1 5.2 1 1 2 4 4 4 1 C2H2 type zinc-finger (2 copies) zf-UBP PF02148.14 KFM01154.1 - 0.014 15.5 5.9 7.3 6.7 0.0 3.7 2 1 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein zf-BED PF02892.10 KFM01154.1 - 0.071 12.8 18.6 1.8 8.4 3.4 5.6 4 1 1 5 5 5 0 BED zinc finger LIM PF00412.17 KFM01154.1 - 0.1 12.6 0.4 0.1 12.6 0.3 3.4 2 1 1 3 3 2 0 LIM domain GAGA PF09237.6 KFM01154.1 - 0.11 12.0 4.1 1.3 8.6 0.1 3.1 2 1 1 3 3 3 0 GAGA factor C1_1 PF00130.17 KFM01154.1 - 0.14 11.8 7.4 0.42 10.3 0.8 3.5 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HYPF PF07503.7 KFM01154.1 - 0.62 9.5 8.0 4.4 6.7 0.6 3.3 3 1 0 3 3 3 0 HypF finger zf-AN1 PF01428.11 KFM01154.1 - 1.9 8.4 10.6 42 4.1 0.2 4.5 4 0 0 4 4 4 0 AN1-like Zinc finger zf-RING_5 PF14634.1 KFM01154.1 - 4 7.2 7.6 84 3.0 0.1 3.7 2 1 0 2 2 2 0 zinc-RING finger domain PI3_PI4_kinase PF00454.22 KFM01155.1 - 2.1e-39 135.4 1.0 1.3e-38 132.8 0.1 2.6 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 KFM01155.1 - 3.4e-33 114.3 0.0 8.1e-33 113.1 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Ipi1_N PF12333.3 KFM01155.1 - 0.0072 16.2 0.5 0.36 10.8 0.1 3.2 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation Serpin PF00079.15 KFM01156.1 - 1.6e-108 363.2 2.3 2e-108 362.8 1.6 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Pec_lyase_C PF00544.14 KFM01156.1 - 0.0074 15.7 0.3 0.014 14.8 0.2 1.4 1 0 0 1 1 1 1 Pectate lyase SNARE PF05739.14 KFM01157.1 - 2.3e-10 40.0 2.1 2.3e-10 40.0 1.4 2.7 3 0 0 3 3 2 1 SNARE domain DUF641 PF04859.7 KFM01157.1 - 0.0013 18.4 5.0 0.083 12.6 0.8 2.5 2 1 0 2 2 2 2 Plant protein of unknown function (DUF641) DUF677 PF05055.7 KFM01157.1 - 0.0019 16.9 4.0 0.73 8.4 0.0 2.9 2 1 1 3 3 3 2 Protein of unknown function (DUF677) IncA PF04156.9 KFM01157.1 - 0.0027 17.3 8.8 0.61 9.6 0.5 2.3 1 1 1 2 2 2 2 IncA protein Fib_alpha PF08702.5 KFM01157.1 - 0.0039 17.3 8.1 0.11 12.5 0.2 2.2 1 1 1 2 2 2 1 Fibrinogen alpha/beta chain family DASH_Duo1 PF08651.5 KFM01157.1 - 0.0055 16.2 1.1 0.55 9.8 0.0 2.5 2 0 0 2 2 2 1 DASH complex subunit Duo1 V-SNARE_C PF12352.3 KFM01157.1 - 0.0078 16.2 4.5 0.12 12.4 0.4 2.8 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus PspA_IM30 PF04012.7 KFM01157.1 - 0.016 14.5 1.2 0.016 14.5 0.8 2.0 2 0 0 2 2 2 0 PspA/IM30 family DUF1664 PF07889.7 KFM01157.1 - 0.041 13.6 4.3 0.5 10.1 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.4 KFM01157.1 - 0.068 13.3 9.5 0.47 10.6 2.4 3.3 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SlyX PF04102.7 KFM01157.1 - 0.14 12.5 6.5 4.2 7.8 0.5 3.3 3 1 1 4 4 3 0 SlyX Baculo_PEP_C PF04513.7 KFM01157.1 - 0.16 11.7 1.9 0.54 10.0 1.1 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FliJ PF02050.11 KFM01157.1 - 0.17 11.9 6.1 0.35 10.9 0.4 2.9 3 0 0 3 3 3 0 Flagellar FliJ protein GLE1 PF07817.8 KFM01157.1 - 0.23 10.3 2.4 0.26 10.1 0.9 1.7 2 0 0 2 2 2 0 GLE1-like protein CCDC-167 PF15188.1 KFM01157.1 - 0.24 11.3 0.1 0.24 11.3 0.1 3.1 3 1 1 4 4 4 0 Coiled-coil domain-containing protein 167 COG5 PF10392.4 KFM01157.1 - 0.26 11.2 4.3 0.64 9.9 1.4 2.6 2 1 0 2 2 2 0 Golgi transport complex subunit 5 Tropomyosin_1 PF12718.2 KFM01157.1 - 0.29 10.9 12.9 0.041 13.7 1.7 3.0 2 1 1 3 3 3 0 Tropomyosin like KxDL PF10241.4 KFM01157.1 - 0.36 10.7 5.5 3.4 7.6 0.1 3.1 2 1 0 3 3 3 0 Uncharacterized conserved protein Syntaxin_2 PF14523.1 KFM01157.1 - 0.44 10.6 5.6 4.3 7.4 0.9 2.3 1 1 0 2 2 2 0 Syntaxin-like protein DUF3552 PF12072.3 KFM01157.1 - 0.52 9.4 9.5 12 5.0 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3552) WEMBL PF05701.6 KFM01157.1 - 0.81 8.0 9.8 0.18 10.2 3.9 1.7 2 0 0 2 2 2 0 Weak chloroplast movement under blue light WXG100 PF06013.7 KFM01157.1 - 0.91 9.5 3.2 44 4.1 0.0 3.2 3 1 0 3 3 3 0 Proteins of 100 residues with WXG APG6 PF04111.7 KFM01157.1 - 0.99 8.3 8.7 0.42 9.6 2.3 1.9 1 1 1 2 2 2 0 Autophagy protein Apg6 Spectrin PF00435.16 KFM01157.1 - 1.7 8.9 7.2 1.1 9.5 0.8 2.8 1 1 0 2 2 2 0 Spectrin repeat ADIP PF11559.3 KFM01157.1 - 2 8.3 12.8 0.042 13.7 2.3 2.5 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Uds1 PF15456.1 KFM01157.1 - 2.6 8.0 11.3 44 4.0 4.3 3.0 2 1 0 2 2 2 0 Up-regulated During Septation FlaC_arch PF05377.6 KFM01157.1 - 3.4 7.6 5.5 24 4.9 1.2 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) TBPIP PF07106.8 KFM01157.1 - 3.6 7.0 10.5 0.37 10.3 2.0 2.6 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Laminin_II PF06009.7 KFM01157.1 - 3.7 7.2 8.0 4.6 7.0 0.7 2.8 2 1 1 3 3 3 0 Laminin Domain II Clathrin PF00637.15 KFM01158.1 - 6.7e-213 696.8 46.6 6.5e-34 116.5 3.6 8.0 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.15 KFM01158.1 - 4.6e-44 145.7 1.0 9.7e-08 31.8 0.0 7.6 7 0 0 7 7 7 7 Clathrin propeller repeat Clathrin_H_link PF13838.1 KFM01158.1 - 3.5e-30 103.6 1.4 1e-29 102.2 0.2 2.5 2 0 0 2 2 2 1 Clathrin-H-link Clathrin-link PF09268.5 KFM01158.1 - 1.6e-11 42.9 0.3 4.8e-11 41.4 0.2 1.9 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.9 KFM01158.1 - 3.5e-05 22.7 4.4 0.0014 17.5 0.1 4.0 3 1 2 5 5 5 1 Coatomer WD associated region TPR_7 PF13176.1 KFM01158.1 - 0.0062 16.2 13.7 0.7 9.8 0.2 6.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFM01158.1 - 0.024 15.2 19.2 63 4.6 0.3 9.5 9 1 2 11 11 11 0 Tetratricopeptide repeat TPR_12 PF13424.1 KFM01158.1 - 7.2 6.6 14.8 2.8 7.9 0.1 6.0 5 2 0 5 5 5 0 Tetratricopeptide repeat TSP_1 PF00090.14 KFM01159.1 - 5.4e-10 39.2 6.1 5.4e-10 39.2 4.2 2.1 2 1 0 2 2 2 1 Thrombospondin type 1 domain Somatomedin_B PF01033.12 KFM01159.1 - 6.2e-08 32.4 18.3 6.2e-08 32.4 12.7 2.4 2 1 0 2 2 2 1 Somatomedin B domain Homeobox PF00046.24 KFM01161.1 - 1.4e-22 79.0 4.6 2.6e-22 78.2 3.2 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFM01161.1 - 0.023 14.3 0.1 0.08 12.6 0.0 1.9 1 0 0 1 1 1 0 Homeobox KN domain HA PF03457.9 KFM01161.1 - 0.042 13.9 2.1 3.1 7.9 0.2 2.3 2 0 0 2 2 2 0 Helicase associated domain Es2 PF09751.4 KFM01162.1 - 1.9e-94 317.4 0.3 1.9e-94 317.4 0.2 2.2 2 1 0 2 2 2 1 Nuclear protein Es2 RED_C PF07807.6 KFM01162.1 - 0.39 10.9 2.7 0.24 11.5 0.1 2.0 3 0 0 3 3 3 0 RED-like protein C-terminal region Lectin_C PF00059.16 KFM01163.1 - 2.3e-18 66.7 1.5 3.8e-18 66.0 0.4 1.8 1 1 1 2 2 2 1 Lectin C-type domain Ldl_recept_a PF00057.13 KFM01163.1 - 8.8e-11 41.5 7.9 8.8e-11 41.5 5.5 3.5 3 0 0 3 3 3 1 Low-density lipoprotein receptor domain class A Herpes_UL45 PF05473.7 KFM01163.1 - 0.0043 16.5 0.4 0.0094 15.3 0.0 1.7 2 0 0 2 2 2 1 UL45 protein Carb_anhydrase PF00194.16 KFM01164.1 - 1.8e-61 207.3 0.0 2e-61 207.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase V-set PF07686.12 KFM01165.1 - 2e-16 59.8 0.1 2.2e-16 59.7 0.1 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 KFM01165.1 - 2.5e-06 27.2 0.0 0.00011 22.0 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.1 KFM01165.1 - 2.8e-05 24.5 0.5 4.9e-05 23.7 0.4 1.4 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFM01165.1 - 0.00013 22.0 1.2 0.00084 19.4 0.8 2.0 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 KFM01165.1 - 0.022 14.8 0.1 0.038 14.1 0.1 1.3 1 1 0 1 1 1 0 Immunoglobulin domain DNA_ligase_ZBD PF03119.11 KFM01165.1 - 0.15 11.7 0.8 0.28 10.9 0.1 1.7 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Ded_cyto PF06920.8 KFM01166.1 - 2.9e-55 186.3 0.5 5.4e-55 185.4 0.4 1.5 1 0 0 1 1 1 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 KFM01166.1 - 3.8e-53 179.8 0.0 1.1e-52 178.3 0.0 1.9 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins Armet PF10208.4 KFM01167.1 - 5.5e-43 146.2 1.7 6e-43 146.1 1.2 1.0 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding CheZ PF04344.8 KFM01167.1 - 0.0044 16.6 0.0 0.0053 16.4 0.0 1.0 1 0 0 1 1 1 1 Chemotaxis phosphatase, CheZ Cauli_DNA-bind PF03310.8 KFM01167.1 - 0.31 10.8 2.4 0.49 10.2 1.7 1.3 1 1 0 1 1 1 0 Caulimovirus DNA-binding protein SPOC PF07744.8 KFM01168.1 - 5.9e-27 94.5 0.0 1.5e-26 93.2 0.0 1.7 1 0 0 1 1 1 1 SPOC domain RRM_1 PF00076.17 KFM01168.1 - 4.2e-25 87.1 0.0 3.8e-14 52.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM01168.1 - 6.2e-19 67.7 0.0 4.1e-08 33.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM01168.1 - 3.8e-15 55.4 0.0 3.4e-07 30.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFM01168.1 - 5e-05 23.0 0.0 0.00044 20.0 0.0 2.3 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 KFM01168.1 - 0.0022 17.6 0.0 0.023 14.4 0.0 2.2 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Asp-B-Hydro_N PF05279.6 KFM01168.1 - 1.6 8.4 7.9 2.5 7.8 5.4 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Pex16 PF08610.5 KFM01168.1 - 3.9 6.3 7.8 6.1 5.7 5.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) RR_TM4-6 PF06459.7 KFM01168.1 - 6.8 6.5 9.3 10 5.9 6.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 LisH PF08513.6 KFM01169.1 - 0.0093 15.7 0.1 0.1 12.4 0.0 2.6 3 0 0 3 3 3 1 LisH FAM176 PF14851.1 KFM01169.1 - 6.9 6.3 13.1 20 4.8 9.1 1.8 1 0 0 1 1 1 0 FAM176 family SNF2_N PF00176.18 KFM01170.1 - 6.6e-53 179.4 0.0 1.2e-52 178.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFM01170.1 - 7.1e-13 48.2 0.0 2e-12 46.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFM01170.1 - 0.00023 21.0 0.0 0.002 17.9 0.0 2.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KFM01170.1 - 0.098 12.7 0.0 0.35 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF506 PF04720.7 KFM01170.1 - 5.4 6.5 10.6 89 2.6 7.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF506) RRM_6 PF14259.1 KFM01171.1 - 3.2e-13 49.4 0.0 1.3e-09 37.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.18 KFM01171.1 - 2e-09 37.0 2.7 5.1e-09 35.7 1.9 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KFM01171.1 - 0.0011 18.8 0.5 0.0011 18.8 0.3 2.5 2 0 0 2 2 2 1 DExH-box splicing factor binding site RRM_5 PF13893.1 KFM01171.1 - 0.035 13.9 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mon1 PF03164.9 KFM01172.1 - 2e-181 603.1 1.0 2.4e-181 602.8 0.7 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Pkinase PF00069.20 KFM01173.1 - 2.3e-31 108.8 0.1 4.7e-18 65.2 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFM01173.1 - 9.1e-13 47.8 0.1 2e-06 27.0 0.2 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase FimP PF09766.4 KFM01174.1 - 0.00053 19.1 6.5 0.00053 19.1 4.5 2.1 2 0 0 2 2 2 1 Fms-interacting protein Myosin_tail_1 PF01576.14 KFM01174.1 - 0.0019 16.0 32.9 0.0027 15.4 22.8 1.1 1 0 0 1 1 1 1 Myosin tail Filament PF00038.16 KFM01174.1 - 0.013 14.9 24.9 0.024 14.1 17.2 1.4 1 0 0 1 1 1 0 Intermediate filament protein WEMBL PF05701.6 KFM01174.1 - 0.03 12.8 36.1 0.1 11.0 9.6 2.3 1 1 1 2 2 2 0 Weak chloroplast movement under blue light SlyX PF04102.7 KFM01174.1 - 0.037 14.3 2.0 0.037 14.3 1.4 4.3 1 1 1 3 3 3 0 SlyX Reo_sigmaC PF04582.7 KFM01174.1 - 0.13 11.4 7.3 2.1 7.4 1.2 2.3 1 1 0 2 2 2 0 Reovirus sigma C capsid protein Spc7 PF08317.6 KFM01174.1 - 0.4 9.2 33.8 0.21 10.1 10.4 3.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Cast PF10174.4 KFM01174.1 - 0.42 8.6 37.3 0.014 13.4 2.4 2.2 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone CENP-F_leu_zip PF10473.4 KFM01174.1 - 0.43 10.4 38.5 11 5.9 9.4 3.4 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 KFM01174.1 - 0.69 9.0 37.5 0.53 9.4 11.2 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.14 KFM01174.1 - 2 6.1 20.3 3 5.5 14.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_13 PF13166.1 KFM01174.1 - 4.1 5.7 25.0 0.38 9.1 13.2 1.9 1 1 1 2 2 2 0 AAA domain DUF1664 PF07889.7 KFM01174.1 - 4.3 7.1 22.5 2.3 8.0 5.8 3.1 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.7 KFM01174.1 - 5 6.8 29.6 0.19 11.4 6.9 2.8 1 1 1 2 2 1 0 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.2 KFM01174.1 - 9.3 6.0 34.0 1.1 9.0 8.8 3.0 2 1 0 2 2 2 0 Tropomyosin like DAG1 PF05454.6 KFM01175.1 - 2.6e-147 489.6 9.2 4.3e-147 488.8 6.3 1.4 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) TMEM154 PF15102.1 KFM01175.1 - 0.0052 16.5 0.1 0.0052 16.5 0.0 2.3 2 0 0 2 2 2 1 TMEM154 protein family GCV_T PF01571.16 KFM01177.1 - 1.1e-56 191.5 0.0 1.4e-56 191.2 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KFM01177.1 - 1.4e-06 28.2 0.2 4.8e-06 26.5 0.1 1.9 1 1 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain UBA_e1_C PF09358.5 KFM01178.1 - 1.8e-07 31.3 0.0 2.2e-07 31.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain She9_MDM33 PF05546.6 KFM01178.1 - 0.022 14.3 0.5 0.027 14.0 0.3 1.0 1 0 0 1 1 1 0 She9 / Mdm33 family HGWP PF03578.10 KFM01178.1 - 0.026 13.8 1.1 0.047 13.0 0.8 1.4 1 0 0 1 1 1 0 HGWP repeat PID_2 PF14719.1 KFM01178.1 - 0.065 12.8 0.0 0.08 12.5 0.0 1.1 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) AAA_25 PF13481.1 KFM01178.1 - 0.067 12.5 0.1 0.078 12.3 0.1 1.2 1 0 0 1 1 1 0 AAA domain IPK PF03770.11 KFM01179.1 - 1e-64 217.8 0.0 1.6e-64 217.1 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase NTP_transferase PF00483.18 KFM01180.1 - 4.3e-21 75.3 0.0 9.6e-21 74.2 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 KFM01180.1 - 1.3e-13 49.7 17.1 5.8e-08 31.8 3.7 3.6 1 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KFM01180.1 - 1.4e-05 24.5 3.1 1.4e-05 24.5 2.1 3.0 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase SPRY PF00622.23 KFM01181.1 - 1.5e-25 89.6 0.1 3e-25 88.7 0.1 1.5 1 0 0 1 1 1 1 SPRY domain zf-C3HC4_3 PF13920.1 KFM01181.1 - 1.3e-08 34.4 8.4 1.3e-08 34.4 5.8 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM01181.1 - 4.9e-05 23.2 13.4 0.00014 21.8 9.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FdhE PF04216.7 KFM01181.1 - 0.0023 17.6 0.5 0.0059 16.3 0.3 1.7 1 0 0 1 1 1 1 Protein involved in formate dehydrogenase formation zf-C3HC4 PF00097.20 KFM01181.1 - 0.014 15.0 14.0 0.039 13.6 9.7 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM01181.1 - 0.023 14.4 12.2 0.057 13.1 8.4 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 KFM01181.1 - 0.061 13.1 10.7 0.19 11.5 7.4 2.0 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.1 KFM01181.1 - 9.3 6.2 10.8 25 4.8 7.5 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-HC5HC2H PF13771.1 KFM01182.1 - 3.8e-15 55.8 2.0 3.8e-15 55.8 1.4 3.4 3 0 0 3 3 3 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 KFM01182.1 - 5.2e-08 32.8 2.4 5.2e-08 32.8 1.7 3.4 2 1 1 3 3 3 1 PHD-zinc-finger like domain Trm112p PF03966.11 KFM01182.1 - 1.1 9.7 4.5 1.8 9.0 0.5 2.6 2 2 0 2 2 2 0 Trm112p-like protein Dispanin PF04505.7 KFM01183.1 - 2.5e-23 81.3 0.0 4e-23 80.7 0.0 1.3 1 0 0 1 1 1 1 Interferon-induced transmembrane protein Cofilin_ADF PF00241.15 KFM01184.1 - 9.5e-38 128.9 0.3 1.1e-37 128.6 0.2 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Rib_recp_KP_reg PF05104.7 KFM01185.1 - 2.3e-33 115.8 39.8 2.3e-33 115.8 27.6 5.0 3 2 1 4 4 4 1 Ribosome receptor lysine/proline rich region OATP PF03137.15 KFM01185.1 - 7 4.5 5.8 0.91 7.4 0.2 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family PX PF00787.19 KFM01186.1 - 2.2e-19 69.2 0.3 2.2e-19 69.2 0.2 2.6 3 1 0 3 3 3 1 PX domain Vps5 PF09325.5 KFM01186.1 - 3.1e-18 65.8 18.3 1.3e-11 44.1 3.0 2.4 2 1 1 3 3 3 2 Vps5 C terminal like BAR PF03114.13 KFM01186.1 - 8.9e-06 25.3 12.7 0.015 14.8 6.8 2.2 2 0 0 2 2 2 2 BAR domain DUF896 PF05979.7 KFM01186.1 - 0.078 12.5 2.8 1.1 8.9 0.1 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) NusB PF01029.13 KFM01186.1 - 0.34 10.8 4.7 0.24 11.3 1.4 2.0 2 0 0 2 2 2 0 NusB family PDDEXK_1 PF12705.2 KFM01187.1 - 1.4e-08 34.4 0.0 6.8e-08 32.2 0.0 2.0 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily zf-C2H2 PF00096.21 KFM01188.1 - 3.6e-18 64.7 26.3 7.6e-05 22.8 1.9 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM01188.1 - 6.8e-18 64.0 23.8 2.3e-09 37.0 0.5 5.1 5 1 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM01188.1 - 1.1e-15 56.6 23.1 6.7e-05 22.9 1.6 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 KFM01188.1 - 0.00018 21.5 16.7 0.0012 18.9 1.7 4.5 3 1 2 5 5 5 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFM01188.1 - 0.00028 20.9 18.6 0.12 12.5 0.4 3.9 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding FYVE PF01363.16 KFM01188.1 - 0.014 15.2 19.7 8.8 6.3 13.7 2.6 1 1 0 1 1 1 0 FYVE zinc finger zf-Di19 PF05605.7 KFM01188.1 - 0.015 15.4 13.3 0.087 12.9 2.8 3.6 2 1 2 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding XPA_N PF01286.13 KFM01188.1 - 0.072 12.7 9.5 3.3 7.4 0.0 4.3 4 0 0 4 4 4 0 XPA protein N-terminal C1_1 PF00130.17 KFM01188.1 - 0.24 11.1 15.8 0.31 10.7 4.7 3.6 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_2 PF12756.2 KFM01188.1 - 0.38 10.8 15.8 1.7 8.7 0.8 3.7 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) A2L_zn_ribbon PF08792.5 KFM01188.1 - 0.61 9.6 0.1 0.61 9.6 0.1 3.8 4 0 0 4 4 4 0 A2L zinc ribbon domain ADK_lid PF05191.9 KFM01188.1 - 1.8 8.2 11.0 3.3 7.4 1.9 4.1 3 1 0 3 3 3 0 Adenylate kinase, active site lid C1_3 PF07649.7 KFM01188.1 - 2 8.4 11.1 11 6.1 0.1 4.1 4 0 0 4 4 4 0 C1-like domain Zn-ribbon_8 PF09723.5 KFM01188.1 - 3.5 7.6 17.8 4.1 7.4 0.5 4.6 3 1 1 4 4 4 0 Zinc ribbon domain zf-H2C2_5 PF13909.1 KFM01188.1 - 4.3 7.7 23.5 2.4 8.5 1.6 4.9 4 2 0 4 4 4 0 C2H2-type zinc-finger domain Rubredoxin PF00301.15 KFM01188.1 - 7.5 6.5 8.2 4.7 7.1 0.0 3.6 4 0 0 4 4 4 0 Rubredoxin Acetyltransf_1 PF00583.19 KFM01190.1 - 2.2e-10 40.4 0.0 5.5e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFM01190.1 - 1.2e-09 38.2 0.0 2.4e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFM01190.1 - 1.6e-09 37.9 0.0 4.1e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFM01190.1 - 5.7e-05 22.7 0.0 0.00011 21.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 KFM01190.1 - 0.00064 19.5 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RNA_pol_Rpc34 PF05158.7 KFM01191.1 - 6.5e-104 347.6 0.7 7.2e-104 347.4 0.5 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit TrmB PF01978.14 KFM01191.1 - 3.3e-05 23.5 0.8 0.004 16.8 0.1 3.1 2 1 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB RPA_C PF08784.6 KFM01191.1 - 0.0045 17.3 2.5 0.36 11.2 0.0 3.3 4 0 0 4 4 4 1 Replication protein A C terminal HTH_24 PF13412.1 KFM01191.1 - 0.017 14.5 0.4 0.059 12.7 0.1 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding B-block_TFIIIC PF04182.7 KFM01191.1 - 0.034 13.9 0.2 0.067 13.0 0.2 1.5 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC TFIIE_alpha PF02002.12 KFM01191.1 - 0.059 12.8 1.4 0.069 12.6 0.3 1.7 2 0 0 2 2 2 0 TFIIE alpha subunit HTH_45 PF14947.1 KFM01191.1 - 0.094 12.5 2.4 0.12 12.1 0.5 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix SCPU PF05229.10 KFM01191.1 - 0.1 12.6 0.1 0.18 11.8 0.0 1.5 1 1 0 1 1 1 0 Spore Coat Protein U domain z-alpha PF02295.12 KFM01191.1 - 0.14 11.9 0.6 0.91 9.3 0.2 2.4 2 0 0 2 2 2 0 Adenosine deaminase z-alpha domain Sec23_trunk PF04811.10 KFM01192.1 - 5.6e-83 278.0 0.0 8.2e-83 277.4 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KFM01192.1 - 6.2e-35 118.7 0.1 1.3e-34 117.7 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KFM01192.1 - 2e-31 108.3 0.0 4.3e-31 107.2 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 KFM01192.1 - 7e-16 57.6 0.0 2.2e-15 56.0 0.0 1.9 1 0 0 1 1 1 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.10 KFM01192.1 - 3.7e-15 55.1 5.8 6.4e-15 54.4 4.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger APP_E2 PF12925.2 KFM01192.1 - 0.1 12.1 0.0 0.34 10.4 0.0 1.8 2 0 0 2 2 2 0 E2 domain of amyloid precursor protein Tyr_Deacylase PF02580.11 KFM01193.1 - 7.5e-42 142.7 0.0 9.2e-42 142.4 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Toprim_C_rpt PF13368.1 KFM01193.1 - 0.028 14.8 0.1 0.05 14.0 0.1 1.4 1 0 0 1 1 1 0 Topoisomerase C-terminal repeat Ribosomal_L7Ae PF01248.21 KFM01195.1 - 6.8e-11 41.5 0.0 8.3e-11 41.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Caenor_Her-1 PF09232.5 KFM01195.1 - 0.018 15.0 0.2 0.022 14.7 0.1 1.1 1 0 0 1 1 1 0 Caenorhabditis elegans Her-1 Sema PF01403.14 KFM01196.1 - 5.2e-145 483.2 0.2 6.7e-145 482.9 0.1 1.1 1 0 0 1 1 1 1 Sema domain PSI PF01437.20 KFM01196.1 - 6.1e-09 35.9 2.5 2e-08 34.2 1.7 2.0 1 0 0 1 1 1 1 Plexin repeat Ig_2 PF13895.1 KFM01196.1 - 0.00024 21.1 0.0 0.0007 19.6 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 KFM01196.1 - 0.00072 19.3 0.3 0.002 17.9 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.20 KFM01196.1 - 0.0038 17.3 0.0 0.016 15.3 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.12 KFM01196.1 - 0.011 15.6 1.4 0.11 12.3 0.2 2.6 2 1 0 2 2 2 0 Immunoglobulin V-set domain XPG_I PF00867.13 KFM01196.1 - 0.046 13.7 0.2 0.22 11.5 0.0 2.1 2 0 0 2 2 2 0 XPG I-region C1-set PF07654.10 KFM01197.1 - 0.019 14.9 0.6 0.03 14.3 0.4 1.4 1 1 0 1 1 1 0 Immunoglobulin C1-set domain I-set PF07679.11 KFM01197.1 - 0.044 13.6 0.1 0.061 13.1 0.1 1.3 1 0 0 1 1 1 0 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM01197.1 - 0.051 13.7 0.1 0.069 13.2 0.1 1.2 1 0 0 1 1 1 0 Immunoglobulin domain Ribosomal_L7Ae PF01248.21 KFM01198.1 - 1.6e-21 75.6 0.3 3e-21 74.7 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CKS PF01111.14 KFM01199.1 - 1.2e-30 105.0 1.3 1.4e-30 104.9 0.9 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit SH3_4 PF06347.8 KFM01199.1 - 0.1 12.1 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial SH3 domain PID PF00640.18 KFM01200.1 - 6.9e-48 162.1 0.0 1.3e-47 161.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SH2 PF00017.19 KFM01200.1 - 9.4e-18 63.8 0.1 3.3e-17 62.0 0.0 2.0 2 0 0 2 2 2 1 SH2 domain PTB PF08416.8 KFM01200.1 - 0.0089 15.9 0.1 0.4 10.5 0.0 2.5 2 0 0 2 2 2 1 Phosphotyrosine-binding domain Spin-Ssty PF02513.12 KFM01202.1 - 1.6e-77 254.8 6.7 1.2e-27 95.2 0.1 3.2 3 0 0 3 3 3 3 Spin/Ssty Family Hydrolase PF00702.21 KFM01203.1 - 4.5e-14 53.3 0.0 2.4e-09 37.9 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFM01203.1 - 1.5e-13 51.3 0.4 9.3e-13 48.7 0.3 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFM01203.1 - 1.2e-08 34.7 0.0 6.3e-08 32.4 0.0 2.3 2 1 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFM01203.1 - 0.0018 17.8 0.6 0.0018 17.8 0.4 2.1 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KFM01203.1 - 0.13 12.4 0.0 0.89 9.7 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HECT PF00632.20 KFM01204.1 - 7.6e-95 317.7 0.6 1.4e-94 316.7 0.1 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) AhpC-TSA_2 PF13911.1 KFM01204.1 - 0.085 12.7 0.0 0.25 11.2 0.0 1.8 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Ion_trans PF00520.26 KFM01205.1 - 4e-17 62.1 2.0 5.9e-17 61.5 1.4 1.3 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.24 KFM01205.1 - 6e-17 61.2 0.0 1.1e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Peptidase_S49_N PF08496.5 KFM01205.1 - 6.3e-05 22.8 8.1 6.3e-05 22.8 5.6 2.8 3 0 0 3 3 3 1 Peptidase family S49 N-terminal CDC45 PF02724.9 KFM01205.1 - 0.0049 14.9 2.0 0.0049 14.9 1.4 1.8 2 0 0 2 2 2 1 CDC45-like protein GAGA_bind PF06217.7 KFM01205.1 - 0.0085 16.0 1.7 0.0085 16.0 1.2 1.6 2 0 0 2 2 2 1 GAGA binding protein-like family Zip PF02535.17 KFM01205.1 - 0.17 10.8 0.8 0.26 10.2 0.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Ion_trans_2 PF07885.11 KFM01205.1 - 0.18 11.5 5.8 0.58 9.9 4.1 2.0 1 1 0 1 1 1 0 Ion channel YqfQ PF14181.1 KFM01205.1 - 2.3 8.2 18.0 6.2 6.8 12.5 1.7 1 0 0 1 1 1 0 YqfQ-like protein NARP1 PF12569.3 KFM01205.1 - 4.9 5.7 24.1 0.18 10.5 9.7 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 DUF1510 PF07423.6 KFM01205.1 - 5.5 6.2 23.5 14 5.0 16.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) VWA_3 PF13768.1 KFM01206.1 - 0.011 15.3 0.5 0.017 14.8 0.3 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain DUF3651 PF12371.3 KFM01207.1 - 2.1e-46 155.7 14.6 2.6e-24 85.0 0.8 5.1 5 0 0 5 5 5 3 Protein of unknown function (DUF3651) C2 PF00168.25 KFM01209.1 - 0.0016 18.2 0.0 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain NHR2 PF08788.6 KFM01209.1 - 0.006 16.0 0.7 0.18 11.3 0.1 2.7 2 0 0 2 2 2 1 NHR2 domain like UNC-50 PF05216.8 KFM01211.1 - 5.9e-90 300.5 22.3 6.7e-90 300.3 15.4 1.0 1 0 0 1 1 1 1 UNC-50 family SH3_2 PF07653.12 KFM01212.1 - 1.3e-22 79.0 0.1 1e-10 40.9 0.1 3.2 3 0 0 3 3 3 2 Variant SH3 domain SH3_9 PF14604.1 KFM01212.1 - 2.3e-13 49.4 0.7 1.1e-10 40.8 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KFM01212.1 - 3.4e-11 42.3 0.5 4.9e-10 38.6 0.0 2.8 2 1 0 2 2 2 1 SH3 domain ZU5 PF00791.15 KFM01212.1 - 1.5e-06 27.8 0.2 3.3e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 ZU5 domain SH3_3 PF08239.6 KFM01212.1 - 0.38 10.9 3.1 0.57 10.4 0.1 2.3 2 0 0 2 2 2 0 Bacterial SH3 domain UDPGT PF00201.13 KFM01213.1 - 1e-207 690.6 0.0 1.2e-207 690.4 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 KFM01213.1 - 7.3e-06 25.7 0.0 1.5e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 KFM01213.1 - 8.9e-05 21.8 0.0 0.0015 17.8 0.0 2.3 2 1 0 2 2 2 1 Glycosyl transferase family 1 Prominin PF05478.6 KFM01213.1 - 0.0043 14.6 0.8 0.0059 14.2 0.5 1.2 1 0 0 1 1 1 1 Prominin Glyco_trans_4_4 PF13579.1 KFM01213.1 - 0.062 13.4 0.0 0.34 11.0 0.0 2.0 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain Glyco_transf_28 PF03033.15 KFM01213.1 - 0.096 12.4 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KFM01214.1 - 1.2e-36 126.3 0.0 1.4e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.13 KFM01215.1 - 5e-41 140.8 0.0 5.5e-41 140.6 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.13 KFM01216.1 - 4.1e-38 131.1 0.3 4.5e-38 131.0 0.2 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.13 KFM01217.1 - 6.4e-40 137.1 0.2 7e-40 137.0 0.1 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_41 PF13844.1 KFM01217.1 - 0.04 11.8 0.1 0.048 11.6 0.1 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 41 UCH PF00443.24 KFM01218.1 - 1.1e-47 162.4 0.8 1.6e-41 142.2 0.2 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFM01218.1 - 2.3e-24 86.3 0.1 5.2e-24 85.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase YukD PF08817.5 KFM01218.1 - 0.072 13.6 0.1 0.96 10.0 0.0 2.9 3 0 0 3 3 3 0 WXG100 protein secretion system (Wss), protein YukD Ank_2 PF12796.2 KFM01219.1 - 9.3e-48 160.5 0.5 2.8e-21 75.6 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFM01219.1 - 3.2e-29 99.2 5.5 5.6e-08 32.2 0.0 5.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 KFM01219.1 - 4.1e-22 77.7 5.9 4.2e-08 33.1 0.0 5.0 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM01219.1 - 4.1e-20 69.8 3.1 1.4e-05 24.8 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 KFM01219.1 - 3.2e-15 56.1 1.1 2.1e-09 37.6 0.0 4.5 3 1 2 5 5 5 3 Ankyrin repeats (many copies) SOCS_box PF07525.11 KFM01219.1 - 3.7e-11 42.6 2.8 7.3e-11 41.7 1.9 1.5 1 0 0 1 1 1 1 SOCS box HLH PF00010.21 KFM01220.1 - 3.1e-17 61.9 0.6 6.1e-17 61.0 0.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Toxin_trans PF07952.7 KFM01220.1 - 0.0091 14.9 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 Clostridium neurotoxin, Translocation domain RNA_pol_I_A49 PF06870.7 KFM01220.1 - 0.039 12.5 0.7 0.053 12.0 0.5 1.1 1 0 0 1 1 1 0 A49-like RNA polymerase I associated factor Hist_deacetyl PF00850.14 KFM01221.1 - 5.6e-93 311.6 0.0 5.6e-93 311.6 0.0 2.6 3 0 0 3 3 3 1 Histone deacetylase domain HDAC4_Gln PF12203.3 KFM01221.1 - 1.4e-35 121.1 46.0 1.4e-35 121.1 31.9 4.0 2 1 2 4 4 4 1 Glutamine rich N terminal domain of histone deacetylase 4 Arb2 PF09757.4 KFM01221.1 - 0.0077 15.6 0.1 0.0077 15.6 0.1 2.0 2 0 0 2 2 2 1 Arb2 domain dNK PF01712.14 KFM01222.1 - 4.1e-22 78.6 0.1 6.4e-22 78.0 0.1 1.3 1 0 0 1 1 1 1 Deoxynucleoside kinase Thymidylate_kin PF02223.12 KFM01222.1 - 0.00024 20.5 0.4 0.00065 19.1 0.3 2.0 1 1 0 1 1 1 1 Thymidylate kinase AAA_17 PF13207.1 KFM01222.1 - 0.0009 20.0 0.1 0.004 17.9 0.0 2.0 2 1 0 2 2 2 1 AAA domain SKI PF01202.17 KFM01222.1 - 0.0022 17.8 0.1 0.29 11.0 0.0 2.5 2 0 0 2 2 2 1 Shikimate kinase Cytidylate_kin2 PF13189.1 KFM01222.1 - 0.017 15.0 0.0 0.066 13.1 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase-like family UPF0079 PF02367.12 KFM01222.1 - 0.034 13.7 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 KFM01222.1 - 0.042 14.1 0.2 17 5.7 0.0 2.7 2 1 1 3 3 3 0 AAA domain AAA_33 PF13671.1 KFM01222.1 - 0.055 13.3 0.0 0.12 12.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain PAS_3 PF08447.6 KFM01223.1 - 8.9e-17 60.9 0.3 2.7e-12 46.6 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.1 KFM01223.1 - 1.9e-12 47.1 0.0 2.2e-09 37.2 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS PF00989.19 KFM01223.1 - 8.8e-12 44.8 0.0 6.9e-10 38.7 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 KFM01223.1 - 2.4e-06 27.8 0.0 0.009 16.3 0.0 2.3 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 KFM01223.1 - 0.1 12.6 0.0 4.9 7.2 0.0 2.4 2 0 0 2 2 2 0 PAS fold DUF4211 PF13926.1 KFM01225.1 - 5.5e-32 110.2 5.6 5.5e-32 110.2 3.9 2.3 3 1 0 3 3 3 1 Domain of unknown function (DUF4211) DUF4196 PF13846.1 KFM01225.1 - 1.6e-07 31.6 3.0 1.6e-07 31.6 2.1 2.8 1 1 0 2 2 2 1 Domain of unknown function (DUF4196) ERF PF04404.7 KFM01225.1 - 0.43 10.0 3.5 0.22 11.0 0.3 2.0 2 0 0 2 2 2 0 ERF superfamily Myotub-related PF06602.9 KFM01228.1 - 5e-147 489.3 0.1 6.7e-147 488.8 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.15 KFM01228.1 - 2.6e-11 42.8 0.0 5.5e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 GRAM domain Y_phosphatase PF00102.22 KFM01228.1 - 0.00011 21.6 0.0 0.00021 20.6 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFM01228.1 - 0.0026 17.3 0.0 0.0057 16.2 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFM01228.1 - 0.0058 16.8 0.0 0.016 15.4 0.0 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family NYD-SP28_assoc PF14775.1 KFM01228.1 - 0.017 14.7 3.9 0.52 10.0 0.5 2.9 3 0 0 3 3 3 0 Sperm tail C-terminal domain Cep57_CLD PF14073.1 KFM01229.1 - 1.6e-66 223.5 37.1 1.6e-66 223.5 25.8 2.5 2 1 0 2 2 2 1 Centrosome localisation domain of Cep57 Cep57_MT_bd PF06657.8 KFM01229.1 - 1.9e-19 69.3 4.3 1.9e-19 69.3 3.0 4.1 2 1 2 4 4 4 1 Centrosome microtubule-binding domain of Cep57 TMF_TATA_bd PF12325.3 KFM01229.1 - 0.0032 17.2 10.0 0.0032 17.2 6.9 4.1 2 2 2 4 4 4 1 TATA element modulatory factor 1 TATA binding IncA PF04156.9 KFM01229.1 - 0.0093 15.5 10.2 0.0093 15.5 7.1 3.3 2 1 1 3 3 3 2 IncA protein Lebercilin PF15619.1 KFM01229.1 - 0.0097 15.3 7.4 0.0097 15.3 5.1 3.6 2 1 1 3 3 3 1 Ciliary protein causing Leber congenital amaurosis disease Flagellin_N PF00669.15 KFM01229.1 - 8.4 6.1 15.2 0.88 9.3 0.8 3.4 3 0 0 3 3 3 0 Bacterial flagellin N-terminal helical region DUF3552 PF12072.3 KFM01230.1 - 0.011 15.0 13.4 0.011 15.0 9.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Myosin_HC-like PF07058.6 KFM01230.1 - 0.053 12.6 8.8 0.21 10.6 4.1 2.2 2 0 0 2 2 2 0 Myosin II heavy chain-like BAF1_ABF1 PF04684.8 KFM01230.1 - 0.18 10.6 15.1 0.22 10.3 10.5 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor ATP-synt_B PF00430.13 KFM01230.1 - 0.78 9.5 10.1 0.21 11.3 4.6 1.8 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Metal_resist PF13801.1 KFM01230.1 - 1 9.3 6.1 5.1 7.1 1.0 2.4 2 0 0 2 2 2 0 Heavy-metal resistance DUF2614 PF11023.3 KFM01230.1 - 2.1 8.1 7.9 1.7 8.4 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) Innate_immun PF12782.2 KFM01230.1 - 2.9 7.0 13.7 5.2 6.1 9.5 1.4 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family GAS PF13851.1 KFM01230.1 - 4 6.5 22.3 0.14 11.3 8.3 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding NicO PF03824.11 KFM01230.1 - 9.9 5.3 9.3 16 4.7 6.4 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein PA26 PF04636.8 KFM01231.1 - 1.7e-212 706.0 0.7 1.9e-212 705.8 0.5 1.0 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) CMD PF02627.15 KFM01231.1 - 0.0011 18.7 0.0 0.0034 17.1 0.0 1.9 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family DnaJ-X PF14308.1 KFM01231.1 - 0.015 14.6 1.1 0.028 13.6 0.8 1.4 1 0 0 1 1 1 0 X-domain of DnaJ-containing ExoD PF06055.7 KFM01231.1 - 0.18 10.8 0.0 0.34 10.0 0.0 1.3 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD Cwf_Cwc_15 PF04889.7 KFM01232.1 - 2.5e-76 256.6 23.5 6.2e-76 255.3 16.3 1.5 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.8 KFM01232.1 - 0.25 9.0 10.7 0.28 8.8 7.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Corona_nucleoca PF00937.13 KFM01232.1 - 0.79 8.6 7.2 1 8.2 5.0 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Med12-LCEWAV PF12145.3 KFM01232.1 - 1.3 7.4 9.5 1.8 6.9 6.6 1.3 1 1 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain PP28 PF10252.4 KFM01232.1 - 5.5 7.0 17.8 0.51 10.4 4.4 2.4 2 0 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 Angiomotin_C PF12240.3 KFM01233.1 - 2.2e-91 304.9 14.5 2.2e-91 304.9 10.0 3.7 3 1 0 3 3 3 2 Angiomotin C terminal NPV_P10 PF05531.7 KFM01233.1 - 1.1 9.5 4.8 0.95 9.7 1.1 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Ank_2 PF12796.2 KFM01234.1 - 3.2e-46 155.5 9.0 8.1e-22 77.3 0.2 2.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFM01234.1 - 1.9e-36 123.8 6.2 3.8e-15 55.9 0.1 4.1 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 KFM01234.1 - 7.6e-34 113.8 4.7 5e-13 48.1 0.0 4.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.1 KFM01234.1 - 4e-25 85.3 3.2 3.3e-07 29.9 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 KFM01234.1 - 7.1e-25 86.4 11.1 1.7e-10 40.8 0.2 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Tcell_CD4_Cterm PF12104.3 KFM01234.1 - 0.069 12.7 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 T cell CD4 receptor C terminal region Mre11_DNA_bind PF04152.9 KFM01235.1 - 8.7e-48 162.4 0.4 8.7e-48 162.4 0.3 2.2 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 KFM01235.1 - 1.2e-27 96.6 2.5 1.7e-27 96.1 1.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KFM01235.1 - 8.1e-08 32.2 0.0 2.9e-07 30.4 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain 7tm_1 PF00001.16 KFM01236.1 - 9.8e-58 195.2 24.3 1.3e-57 194.8 16.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM01236.1 - 9.3e-18 64.3 23.5 1.2e-17 63.9 16.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Cu-oxidase_3 PF07732.10 KFM01237.1 - 6.4e-31 106.5 0.9 2.3e-10 40.2 0.0 5.2 5 0 0 5 5 5 3 Multicopper oxidase Cu-oxidase_2 PF07731.9 KFM01237.1 - 2.4e-20 72.4 11.2 1.5e-10 40.6 3.3 5.4 5 1 0 5 5 5 3 Multicopper oxidase L6_membrane PF05805.7 KFM01238.1 - 2e-56 190.6 14.0 2.2e-56 190.5 9.7 1.0 1 0 0 1 1 1 1 L6 membrane protein SSF PF00474.12 KFM01239.1 - 7.2e-26 90.7 18.9 1.1e-25 90.1 13.1 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family V-set PF07686.12 KFM01240.1 - 7.1e-08 32.3 0.4 1.1e-07 31.6 0.3 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain Receptor_2B4 PF11465.3 KFM01240.1 - 0.0012 18.7 0.1 0.0019 18.0 0.1 1.3 1 0 0 1 1 1 1 Natural killer cell receptor 2B4 I-set PF07679.11 KFM01240.1 - 0.013 15.3 0.3 0.036 13.9 0.2 1.8 1 1 0 1 1 1 0 Immunoglobulin I-set domain Herpes_gE PF02480.11 KFM01240.1 - 0.27 9.4 2.2 0.29 9.3 0.1 1.7 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E Med17 PF10156.4 KFM01241.1 - 2.7e-112 375.4 1.1 3.2e-112 375.1 0.8 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex DUF1907 PF08925.6 KFM01242.1 - 1.9e-129 430.8 0.0 2.1e-129 430.6 0.0 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) TAF1D PF15333.1 KFM01243.1 - 2.7e-51 174.4 22.1 3.6e-50 170.7 15.3 2.4 1 1 0 1 1 1 1 TATA box-binding protein-associated factor 1D ALMS_motif PF15309.1 KFM01245.1 - 2.6e-20 72.6 27.9 4.6e-20 71.8 19.3 1.3 1 0 0 1 1 1 1 ALMS motif ICAT PF06384.6 KFM01245.1 - 0.0063 16.2 2.2 0.008 15.9 0.1 2.3 2 0 0 2 2 2 1 Beta-catenin-interacting protein ICAT UPF0102 PF02021.12 KFM01245.1 - 0.31 10.9 5.1 0.67 9.9 0.2 2.3 1 1 1 2 2 2 0 Uncharacterised protein family UPF0102 Snapin_Pallidin PF14712.1 KFM01247.1 - 0.11 12.7 5.2 0.12 12.7 3.6 1.2 1 0 0 1 1 1 0 Snapin/Pallidin DUF2756 PF10956.3 KFM01247.1 - 2.3 8.5 9.1 9.7 6.5 6.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2756) CPSase_L_D3 PF02787.14 KFM01249.1 - 0.0028 17.4 0.6 0.0041 16.8 0.4 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain DUF1690 PF07956.6 KFM01249.1 - 0.086 12.8 7.6 0.059 13.3 4.2 1.4 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) FUSC-like PF12805.2 KFM01249.1 - 0.28 10.0 6.7 0.32 9.8 4.7 1.1 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS Phage_GPO PF05929.6 KFM01249.1 - 0.33 10.1 4.9 0.38 9.9 3.4 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase vATP-synt_E PF01991.13 KFM01249.1 - 0.63 9.2 12.6 0.7 9.1 8.7 1.0 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit DUF4519 PF15012.1 KFM01250.1 - 1.1e-27 95.6 5.0 1.2e-27 95.5 3.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4519) DUF4448 PF14610.1 KFM01250.1 - 3.4e-05 23.4 0.1 3.7e-05 23.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF912 PF06024.7 KFM01250.1 - 0.00037 20.4 0.0 0.00038 20.4 0.0 1.0 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3899 PF13038.1 KFM01250.1 - 0.00042 20.4 0.0 0.00044 20.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3899) DUF2232 PF09991.4 KFM01250.1 - 0.0019 17.2 0.0 0.0021 17.1 0.0 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2232) Vma12 PF11712.3 KFM01250.1 - 0.005 16.5 0.0 0.0054 16.4 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF3753 PF12575.3 KFM01250.1 - 0.015 15.0 0.1 0.018 14.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) DUF106 PF01956.11 KFM01250.1 - 0.024 14.1 0.1 0.026 14.0 0.0 1.0 1 0 0 1 1 1 0 Integral membrane protein DUF106 FTCD_C PF04961.7 KFM01250.1 - 0.034 13.5 0.1 0.034 13.5 0.1 1.0 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase DUF3357 PF11837.3 KFM01250.1 - 0.037 13.8 0.0 0.04 13.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) DUF3290 PF11694.3 KFM01250.1 - 0.06 13.0 0.3 0.076 12.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) DUF2077 PF09850.4 KFM01250.1 - 0.063 12.6 0.0 0.069 12.5 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) AHSP PF09236.5 KFM01250.1 - 0.069 13.3 0.0 0.081 13.1 0.0 1.2 1 0 0 1 1 1 0 Alpha-haemoglobin stabilising protein DUF4064 PF13273.1 KFM01250.1 - 0.076 13.1 0.0 0.085 12.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) CoatB PF10389.4 KFM01250.1 - 0.082 12.7 0.1 0.11 12.4 0.1 1.1 1 0 0 1 1 1 0 Bacteriophage coat protein B DUF2208 PF09973.4 KFM01250.1 - 0.084 12.0 0.0 0.084 12.0 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) CD34_antigen PF06365.7 KFM01250.1 - 0.099 12.2 0.0 0.099 12.2 0.0 1.0 1 0 0 1 1 1 0 CD34/Podocalyxin family ODV-E18 PF10717.4 KFM01250.1 - 0.1 12.0 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 RskA PF10099.4 KFM01250.1 - 0.1 12.3 0.0 0.1 12.3 0.0 1.0 1 0 0 1 1 1 0 Anti-sigma-K factor rskA UPF0233 PF06781.7 KFM01250.1 - 0.11 12.1 0.1 0.11 12.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) DUF2116 PF09889.4 KFM01250.1 - 1.5 8.6 3.6 2.3 8.0 2.5 1.4 1 1 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Protocadherin PF08374.6 KFM01250.1 - 2.6 7.6 4.8 3.3 7.3 3.3 1.3 1 1 0 1 1 1 0 Protocadherin Tup_N PF08581.5 KFM01251.1 - 0.00047 20.2 6.8 0.00047 20.2 4.7 8.3 7 4 2 10 10 10 2 Tup N-terminal RVT_1 PF00078.22 KFM01252.1 - 0.076 12.3 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Hormone_recep PF00104.25 KFM01253.1 - 1.1e-19 70.4 0.0 1.5e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Connexin PF00029.14 KFM01254.1 - 2.2e-41 140.2 0.0 3.1e-41 139.7 0.0 1.2 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 KFM01254.1 - 2.4e-21 75.3 0.1 6.7e-21 73.8 0.1 1.8 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain DNA_topoisoIV PF00521.15 KFM01255.1 - 2.7e-133 444.9 0.2 6.9e-133 443.5 0.0 1.8 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 KFM01255.1 - 1.9e-34 118.3 1.3 5.1e-34 116.9 0.9 1.8 1 0 0 1 1 1 1 DNA gyrase B DTHCT PF08070.6 KFM01255.1 - 6.1e-17 62.0 12.3 6.1e-17 62.0 8.5 5.4 4 1 2 6 6 6 1 DTHCT (NUC029) region Toprim PF01751.17 KFM01255.1 - 9.4e-15 54.4 0.7 3e-14 52.7 0.0 2.3 2 0 0 2 2 2 1 Toprim domain HATPase_c PF02518.21 KFM01255.1 - 1.3e-10 40.9 0.0 4.4e-10 39.2 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Thyroglobulin_1 PF00086.13 KFM01256.1 - 8.1e-19 66.7 0.7 8.1e-19 66.7 0.5 2.0 2 1 1 3 3 3 1 Thyroglobulin type-1 repeat PTB PF08416.8 KFM01257.1 - 8.1e-30 103.4 0.0 1.2e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SH2 PF00017.19 KFM01257.1 - 2.4e-10 40.0 0.0 4.8e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 SH2 domain PID PF00640.18 KFM01257.1 - 0.0066 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) HMG_box PF00505.14 KFM01258.1 - 2.9e-18 65.8 1.6 2.9e-18 65.8 1.1 2.4 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFM01258.1 - 1.3e-06 28.6 0.6 1.3e-06 28.6 0.4 2.5 2 0 0 2 2 2 1 HMG-box domain Filament PF00038.16 KFM01259.1 - 1.5e-23 83.7 17.9 2.5e-23 83.0 12.4 1.3 1 0 0 1 1 1 1 Intermediate filament protein DUF773 PF05600.7 KFM01259.1 - 0.0015 17.4 3.3 0.0019 17.0 2.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF773) V_ATPase_I PF01496.14 KFM01259.1 - 0.0023 15.8 6.6 0.0028 15.6 4.6 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family FH2 PF02181.18 KFM01259.1 - 0.0037 16.2 1.9 0.0056 15.6 1.3 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain APG6 PF04111.7 KFM01259.1 - 0.011 14.7 8.8 0.017 14.1 6.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 SYCE1 PF15233.1 KFM01259.1 - 0.059 13.2 13.9 0.14 12.0 9.7 1.6 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 FUSC PF04632.7 KFM01259.1 - 0.086 11.2 2.1 0.095 11.1 1.4 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4201 PF13870.1 KFM01259.1 - 0.2 11.0 15.1 0.35 10.2 10.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF1664 PF07889.7 KFM01259.1 - 1.4 8.7 6.4 0.96 9.2 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) FliJ PF02050.11 KFM01259.1 - 2.1 8.3 16.4 7.2 6.6 6.1 2.4 1 1 1 2 2 2 0 Flagellar FliJ protein SPX PF03105.14 KFM01259.1 - 3.6 7.2 6.1 5.4 6.7 4.2 1.5 1 1 0 1 1 1 0 SPX domain IncA PF04156.9 KFM01259.1 - 4 6.9 13.0 7.1 6.1 9.0 1.5 1 0 0 1 1 1 0 IncA protein Filament PF00038.16 KFM01260.1 - 2.7e-114 381.8 25.2 3.1e-114 381.6 17.5 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 KFM01260.1 - 0.0036 17.0 2.0 0.0036 17.0 1.4 3.7 3 1 1 4 4 4 1 TPR/MLP1/MLP2-like protein GAS PF13851.1 KFM01260.1 - 0.021 14.0 19.7 0.14 11.3 0.5 3.0 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Prefoldin PF02996.12 KFM01260.1 - 0.048 13.3 15.7 0.036 13.7 1.0 4.2 4 0 0 4 4 4 0 Prefoldin subunit T2SM PF04612.7 KFM01260.1 - 0.065 13.0 0.3 0.065 13.0 0.2 2.5 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M ADIP PF11559.3 KFM01260.1 - 0.066 13.1 24.7 3 7.7 8.5 3.8 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding CCDC92 PF14916.1 KFM01260.1 - 0.072 12.6 5.1 1.6 8.4 0.1 3.5 3 0 0 3 3 3 0 Coiled-coil domain of unknown function Myosin_tail_1 PF01576.14 KFM01260.1 - 0.076 10.7 30.6 0.043 11.5 5.7 2.5 2 1 1 3 3 3 0 Myosin tail Matrilin_ccoil PF10393.4 KFM01260.1 - 0.18 11.2 1.4 8 5.9 0.1 2.7 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin FlxA PF14282.1 KFM01260.1 - 0.19 11.6 22.7 3.1 7.7 0.1 3.7 3 1 0 3 3 3 0 FlxA-like protein Prefoldin_2 PF01920.15 KFM01260.1 - 0.26 11.0 24.8 5.8 6.7 1.6 4.9 3 2 1 4 4 4 0 Prefoldin subunit Bacillus_HBL PF05791.6 KFM01260.1 - 0.28 10.5 11.4 0.075 12.3 2.6 2.7 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) ATG16 PF08614.6 KFM01260.1 - 1 9.1 29.1 5.2 6.8 4.0 3.9 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Tho2 PF11262.3 KFM01260.1 - 1.1 8.2 5.3 0.28 10.2 1.3 1.7 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF972 PF06156.8 KFM01260.1 - 1.4 9.2 24.5 1.3 9.3 1.0 5.0 2 2 3 5 5 5 0 Protein of unknown function (DUF972) Atg14 PF10186.4 KFM01260.1 - 1.5 7.7 17.9 2.5 6.9 1.0 2.6 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DivIC PF04977.10 KFM01260.1 - 1.6 8.2 29.3 0.72 9.3 1.1 5.5 6 0 0 6 6 6 0 Septum formation initiator CALCOCO1 PF07888.6 KFM01260.1 - 1.6 6.9 21.8 0.11 10.7 8.5 2.0 1 1 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like FlaC_arch PF05377.6 KFM01260.1 - 2.1 8.3 11.5 9.6 6.1 0.4 4.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) RasGAP_C PF03836.10 KFM01260.1 - 3 7.5 16.1 6 6.5 2.1 3.5 1 1 1 3 3 3 0 RasGAP C-terminus DUF4200 PF13863.1 KFM01260.1 - 3.2 7.7 27.1 0.25 11.3 0.8 4.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4200) SlyX PF04102.7 KFM01260.1 - 3.4 8.1 17.2 26 5.2 0.3 4.2 3 1 1 4 4 4 0 SlyX TBPIP PF07106.8 KFM01260.1 - 3.4 7.1 22.4 1.2 8.6 2.3 4.1 3 1 0 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) APG6 PF04111.7 KFM01260.1 - 4.1 6.3 27.8 0.82 8.6 0.8 2.5 3 0 0 3 3 3 0 Autophagy protein Apg6 IFP_35_N PF07334.8 KFM01260.1 - 8.8 6.3 9.0 9.7 6.2 1.0 3.1 2 1 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus IncA PF04156.9 KFM01260.1 - 9.8 5.7 31.8 2.7 7.5 11.3 3.5 1 1 1 2 2 2 0 IncA protein Filament PF00038.16 KFM01262.1 - 4e-85 286.0 33.9 4.7e-85 285.7 23.5 1.0 1 0 0 1 1 1 1 Intermediate filament protein IncA PF04156.9 KFM01262.1 - 9.4e-05 22.0 22.8 0.14 11.7 0.0 3.7 2 1 1 3 3 3 2 IncA protein DUF4296 PF14129.1 KFM01262.1 - 0.017 15.2 5.9 0.038 14.1 0.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4296) DUF3510 PF12022.3 KFM01262.1 - 0.031 14.3 2.4 0.1 12.7 1.7 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) BRAP2 PF07576.7 KFM01262.1 - 0.077 12.5 0.8 0.51 9.9 0.1 2.2 2 0 0 2 2 2 0 BRCA1-associated protein 2 ADIP PF11559.3 KFM01262.1 - 0.17 11.8 26.0 0.32 10.9 6.7 3.1 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.4 KFM01262.1 - 0.22 11.4 28.2 0.24 11.2 4.3 4.0 1 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4140 PF13600.1 KFM01262.1 - 5.2 7.5 17.8 2.7 8.5 0.6 4.5 3 1 2 5 5 5 0 N-terminal domain of unknown function (DUF4140) Filament PF00038.16 KFM01263.1 - 1.1e-116 389.7 31.9 1.2e-116 389.5 22.1 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 KFM01263.1 - 9.8e-05 22.1 1.5 9.8e-05 22.1 1.0 3.4 3 1 0 3 3 3 1 TPR/MLP1/MLP2-like protein Myosin_tail_1 PF01576.14 KFM01263.1 - 0.00078 17.3 28.1 0.019 12.7 6.5 2.7 1 1 1 2 2 2 2 Myosin tail DUF4618 PF15397.1 KFM01263.1 - 0.0036 16.6 7.8 0.0036 16.6 5.4 2.9 3 1 1 4 4 4 1 Domain of unknown function (DUF4618) FlaC_arch PF05377.6 KFM01263.1 - 0.097 12.5 18.2 0.12 12.2 0.1 4.2 5 0 0 5 5 3 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.7 KFM01263.1 - 0.27 11.0 13.9 2.4 7.9 0.2 3.8 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.1 KFM01263.1 - 0.29 10.3 22.6 0.13 11.3 4.2 3.2 2 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding DivIC PF04977.10 KFM01263.1 - 0.3 10.5 25.8 0.83 9.1 0.8 4.9 5 0 0 5 5 5 0 Septum formation initiator DUF4407 PF14362.1 KFM01263.1 - 0.45 9.4 16.7 0.32 9.9 5.5 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) HR1 PF02185.11 KFM01263.1 - 0.56 9.9 21.2 0.37 10.5 1.7 4.1 3 1 1 4 4 3 0 Hr1 repeat ADIP PF11559.3 KFM01263.1 - 0.63 9.9 23.4 2.5 7.9 0.6 4.2 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding Transposase_22 PF02994.9 KFM01263.1 - 0.77 8.1 16.9 0.27 9.6 5.6 2.2 1 1 0 2 2 2 0 L1 transposable element IncA PF04156.9 KFM01263.1 - 0.79 9.2 32.5 4 6.9 3.1 3.5 3 1 0 3 3 3 0 IncA protein Fib_alpha PF08702.5 KFM01263.1 - 1.9 8.5 19.1 1.2 9.2 1.1 3.8 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family SlyX PF04102.7 KFM01263.1 - 2.3 8.6 23.1 0.25 11.7 1.2 5.0 4 1 1 5 5 5 0 SlyX DUF1664 PF07889.7 KFM01263.1 - 2.5 7.9 14.5 0.64 9.8 0.8 3.6 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) DUF972 PF06156.8 KFM01263.1 - 4.8 7.5 24.2 6.9 7.0 1.6 4.9 2 2 4 6 6 6 0 Protein of unknown function (DUF972) Bap31 PF05529.7 KFM01263.1 - 4.9 6.5 11.4 0.72 9.2 0.9 2.9 3 0 0 3 3 3 0 B-cell receptor-associated protein 31-like Prefoldin PF02996.12 KFM01263.1 - 5.4 6.6 17.1 2 8.1 1.4 4.0 4 0 0 4 4 4 0 Prefoldin subunit WXG100 PF06013.7 KFM01263.1 - 5.6 7.0 10.0 6.7 6.7 0.8 4.0 3 1 0 3 3 3 0 Proteins of 100 residues with WXG DUF2115 PF09888.4 KFM01263.1 - 6.8 6.7 6.5 1.3 9.0 0.4 2.6 1 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2115) CENP-F_leu_zip PF10473.4 KFM01263.1 - 7.2 6.4 30.1 12 5.7 5.8 4.3 2 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 KFM01263.1 - 8.3 5.3 24.9 0.65 8.9 2.5 2.8 2 2 0 2 2 2 0 Autophagy protein Apg6 Atg14 PF10186.4 KFM01263.1 - 8.3 5.2 20.5 3.5 6.5 2.1 3.3 1 1 1 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 FlxA PF14282.1 KFM01263.1 - 9.3 6.2 21.2 4.2 7.3 0.1 3.8 3 1 1 4 4 4 0 FlxA-like protein Filament PF00038.16 KFM01264.1 - 1.4e-89 300.6 23.1 1.6e-89 300.4 16.0 1.0 1 0 0 1 1 1 1 Intermediate filament protein Myosin_tail_1 PF01576.14 KFM01264.1 - 7.5e-06 23.9 24.9 0.0004 18.2 1.1 2.9 2 1 0 3 3 3 3 Myosin tail Transposase_22 PF02994.9 KFM01264.1 - 0.0015 17.1 7.3 0.0015 17.1 5.1 2.0 1 1 1 2 2 2 1 L1 transposable element DUF1664 PF07889.7 KFM01264.1 - 0.0057 16.4 13.2 0.062 13.1 1.6 3.1 2 1 1 3 3 3 1 Protein of unknown function (DUF1664) COG2 PF06148.6 KFM01264.1 - 0.0069 16.2 5.1 0.03 14.2 0.0 3.0 1 1 2 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Bacillus_HBL PF05791.6 KFM01264.1 - 0.0077 15.6 3.1 0.0077 15.6 2.2 2.4 1 1 1 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) Prefoldin PF02996.12 KFM01264.1 - 0.0095 15.5 12.9 0.092 12.3 4.5 3.7 1 1 0 2 2 2 1 Prefoldin subunit DUF2773 PF10971.3 KFM01264.1 - 0.024 14.6 0.8 0.22 11.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2773) Baculo_PEP_C PF04513.7 KFM01264.1 - 0.045 13.5 11.8 2.3 8.0 0.8 3.4 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2551 PF10826.3 KFM01264.1 - 0.08 12.8 0.2 3.2 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2551) DivIC PF04977.10 KFM01264.1 - 0.13 11.8 16.6 0.2 11.1 0.6 3.7 2 1 2 4 4 4 0 Septum formation initiator TPR_MLP1_2 PF07926.7 KFM01264.1 - 0.16 11.6 21.8 0.17 11.6 0.4 3.1 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein FlxA PF14282.1 KFM01264.1 - 0.16 11.8 16.1 14 5.6 6.4 3.5 2 2 1 3 3 3 0 FlxA-like protein Reo_sigmaC PF04582.7 KFM01264.1 - 0.16 11.0 6.2 0.56 9.3 1.3 2.1 1 1 0 2 2 2 0 Reovirus sigma C capsid protein DUF1409 PF07197.7 KFM01264.1 - 0.17 11.9 2.5 0.96 9.5 1.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1409) Lebercilin PF15619.1 KFM01264.1 - 0.28 10.5 18.7 0.84 9.0 9.2 2.9 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF2344 PF10105.4 KFM01264.1 - 0.34 10.3 3.0 0.36 10.2 1.3 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) WXG100 PF06013.7 KFM01264.1 - 0.41 10.6 11.6 2.8 8.0 2.6 4.2 1 1 3 4 4 4 0 Proteins of 100 residues with WXG ParB PF08775.5 KFM01264.1 - 0.43 10.8 6.9 0.67 10.2 0.1 3.1 2 1 0 3 3 3 0 ParB family DUF310 PF03750.8 KFM01264.1 - 0.54 10.4 6.2 0.63 10.2 0.9 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF310) DUF2408 PF10303.4 KFM01264.1 - 0.73 9.9 11.9 23 5.1 8.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Sipho_Gp157 PF05565.6 KFM01264.1 - 0.73 9.3 10.8 1.2 8.7 0.3 2.8 2 1 1 3 3 3 0 Siphovirus Gp157 Ax_dynein_light PF10211.4 KFM01264.1 - 0.97 9.2 15.8 0.22 11.3 0.2 3.6 2 1 0 3 3 3 0 Axonemal dynein light chain DUF342 PF03961.8 KFM01264.1 - 1.2 7.4 11.6 20 3.4 7.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF342) ADIP PF11559.3 KFM01264.1 - 1.8 8.4 21.4 2.1 8.2 0.5 3.3 2 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.6 KFM01264.1 - 2.3 8.1 11.6 4.3 7.3 0.0 4.2 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) CENP-F_leu_zip PF10473.4 KFM01264.1 - 2.5 7.9 25.9 5.1 6.9 2.9 3.8 2 2 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF972 PF06156.8 KFM01264.1 - 2.5 8.4 18.0 1.5 9.1 0.3 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF972) SlyX PF04102.7 KFM01264.1 - 5.6 7.4 20.1 6.1 7.3 0.4 4.4 2 1 2 4 4 4 0 SlyX DUF4407 PF14362.1 KFM01264.1 - 6.5 5.6 14.0 2.7 6.8 6.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4200 PF13863.1 KFM01264.1 - 9.2 6.2 22.6 0.63 10.0 1.1 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) Filament PF00038.16 KFM01265.1 - 4.1e-23 82.3 11.5 4.8e-23 82.1 7.9 1.0 1 0 0 1 1 1 1 Intermediate filament protein GAS PF13851.1 KFM01265.1 - 0.0098 15.1 2.4 0.012 14.8 1.7 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding TACC PF05010.9 KFM01265.1 - 0.052 13.3 5.1 0.097 12.4 0.5 2.0 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) Kinetocho_Slk19 PF12709.2 KFM01265.1 - 0.073 13.1 1.2 0.13 12.3 0.3 1.9 1 1 1 2 2 2 0 Central kinetochore-associated Uso1_p115_C PF04871.8 KFM01265.1 - 0.098 12.5 3.9 0.14 12.1 2.7 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF342 PF03961.8 KFM01265.1 - 0.1 11.0 2.4 0.11 10.8 1.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) YgaB PF14182.1 KFM01265.1 - 0.13 12.5 8.2 0.047 13.9 2.7 2.0 1 1 0 2 2 2 0 YgaB-like protein WEMBL PF05701.6 KFM01265.1 - 0.31 9.4 4.4 0.34 9.2 3.1 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light FliJ PF02050.11 KFM01265.1 - 0.45 10.5 9.9 0.26 11.3 5.8 1.5 1 1 1 2 2 2 0 Flagellar FliJ protein IncA PF04156.9 KFM01265.1 - 0.46 10.0 9.8 0.56 9.7 6.8 1.1 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 KFM01265.1 - 0.49 10.7 3.5 0.25 11.6 0.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF972) HR1 PF02185.11 KFM01265.1 - 0.5 10.1 9.6 0.38 10.5 3.9 2.0 2 0 0 2 2 2 0 Hr1 repeat APG6 PF04111.7 KFM01265.1 - 0.84 8.6 5.7 0.98 8.4 4.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 FlaC_arch PF05377.6 KFM01265.1 - 0.9 9.4 3.5 0.68 9.8 0.6 2.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) V-SNARE PF05008.10 KFM01265.1 - 2.2 8.5 9.5 16 5.7 6.1 2.1 1 1 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus ADIP PF11559.3 KFM01265.1 - 2.7 7.8 8.1 0.55 10.1 1.5 1.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Filament PF00038.16 KFM01266.1 - 6.8e-97 324.7 33.1 7.8e-97 324.4 22.9 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 KFM01266.1 - 1.1e-06 28.3 0.5 1.1e-06 28.3 0.3 3.6 3 1 1 4 4 4 2 TPR/MLP1/MLP2-like protein WEMBL PF05701.6 KFM01266.1 - 0.00071 18.1 19.9 0.035 12.5 9.1 2.3 1 1 0 2 2 2 2 Weak chloroplast movement under blue light Tropomyosin_1 PF12718.2 KFM01266.1 - 0.001 18.9 26.1 0.0011 18.8 5.9 3.8 2 1 0 3 3 3 2 Tropomyosin like BAR_3_WASP_bdg PF10456.4 KFM01266.1 - 0.014 14.6 0.8 0.98 8.6 0.0 2.3 2 0 0 2 2 2 0 WASP-binding domain of Sorting nexin protein DUF2312 PF10073.4 KFM01266.1 - 0.015 14.6 0.1 0.07 12.4 0.1 2.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) Lectin_N PF03954.9 KFM01266.1 - 0.02 14.2 7.2 1.3 8.3 1.0 3.4 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain IncA PF04156.9 KFM01266.1 - 0.026 14.1 36.2 0.034 13.7 13.9 3.2 1 1 2 3 3 3 0 IncA protein AAA_13 PF13166.1 KFM01266.1 - 0.077 11.4 17.5 2 6.8 12.1 2.3 1 1 0 1 1 1 0 AAA domain Transposase_22 PF02994.9 KFM01266.1 - 0.11 10.9 21.2 0.075 11.5 8.8 2.5 1 1 1 2 2 2 0 L1 transposable element HOOK PF05622.7 KFM01266.1 - 0.33 8.6 27.8 3.9 5.1 19.3 2.3 1 1 0 1 1 1 0 HOOK protein TACC PF05010.9 KFM01266.1 - 0.63 9.7 19.0 2.9 7.6 9.4 3.0 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) Tho2 PF11262.3 KFM01266.1 - 1.1 8.2 10.7 0.067 12.2 2.4 2.4 2 1 1 3 3 3 0 Transcription factor/nuclear export subunit protein 2 V_ATPase_I PF01496.14 KFM01266.1 - 1.1 7.0 16.6 1.6 6.4 11.4 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.6 KFM01266.1 - 2.3 6.7 25.2 0.072 11.7 8.6 3.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Laminin_II PF06009.7 KFM01266.1 - 2.4 7.9 14.3 0.48 10.1 3.2 3.2 2 2 1 3 3 3 0 Laminin Domain II BLOC1_2 PF10046.4 KFM01266.1 - 2.8 8.1 22.2 1.1 9.4 4.6 4.2 4 1 0 5 5 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4200 PF13863.1 KFM01266.1 - 2.9 7.8 31.3 0.32 10.9 0.1 4.4 3 2 1 4 4 3 0 Domain of unknown function (DUF4200) Gp58 PF07902.6 KFM01266.1 - 3.3 5.8 9.0 2 6.5 4.9 1.6 1 1 1 2 2 2 0 gp58-like protein DUF4140 PF13600.1 KFM01266.1 - 4.4 7.8 14.5 11 6.5 1.1 4.1 3 1 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) PspA_IM30 PF04012.7 KFM01266.1 - 4.5 6.5 21.9 5.8 6.2 2.3 4.2 2 1 2 4 4 4 0 PspA/IM30 family Phage_GP20 PF06810.6 KFM01266.1 - 4.7 6.6 19.5 0.051 13.0 4.0 3.2 2 2 2 4 4 4 0 Phage minor structural protein GP20 DUF848 PF05852.6 KFM01266.1 - 6.5 6.5 16.7 4.9 6.9 4.6 3.9 3 1 1 4 4 4 0 Gammaherpesvirus protein of unknown function (DUF848) ADIP PF11559.3 KFM01266.1 - 6.9 6.5 31.3 0.78 9.6 8.2 4.2 2 2 2 4 4 4 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.7 KFM01266.1 - 8.3 6.2 15.3 0.81 9.4 2.2 3.8 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.5 KFM01266.1 - 8.5 6.4 22.4 19 5.3 6.7 3.5 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family Kinetocho_Slk19 PF12709.2 KFM01266.1 - 9.7 6.3 25.1 1.2 9.2 2.7 5.0 4 1 1 5 5 5 0 Central kinetochore-associated Filament PF00038.16 KFM01267.1 - 2.2e-70 237.5 24.4 2.5e-70 237.4 16.9 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 KFM01267.1 - 8.8e-05 22.2 2.7 8.8e-05 22.2 1.9 3.0 3 0 0 3 3 3 1 TPR/MLP1/MLP2-like protein DUF4200 PF13863.1 KFM01267.1 - 0.0013 18.6 26.2 0.011 15.6 0.1 3.8 3 1 1 4 4 4 2 Domain of unknown function (DUF4200) Vps5 PF09325.5 KFM01267.1 - 0.0022 17.2 6.1 0.0022 17.2 4.2 2.1 2 1 0 2 2 2 1 Vps5 C terminal like GAS PF13851.1 KFM01267.1 - 0.009 15.2 1.9 0.009 15.2 1.3 3.3 1 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding HXXSHH PF07586.6 KFM01267.1 - 0.013 14.3 0.2 0.03 13.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) CENP-F_leu_zip PF10473.4 KFM01267.1 - 0.027 14.3 30.8 0.34 10.7 5.5 4.4 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lectin_N PF03954.9 KFM01267.1 - 0.029 13.7 5.9 0.96 8.8 0.6 2.9 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain ACP PF06857.6 KFM01267.1 - 0.042 13.7 2.7 1.3 9.0 0.2 3.0 2 1 1 3 3 3 0 Malonate decarboxylase delta subunit (MdcD) HTH_42 PF06224.7 KFM01267.1 - 0.044 13.1 0.0 0.092 12.0 0.0 1.5 2 0 0 2 2 2 0 Winged helix DNA-binding domain DASH_Dam1 PF08653.5 KFM01267.1 - 0.11 12.2 0.9 11 5.9 0.2 2.9 2 0 0 2 2 2 0 DASH complex subunit Dam1 Phage_Mu_Gam PF07352.7 KFM01267.1 - 0.14 11.7 15.3 0.99 8.9 1.9 3.0 2 2 0 2 2 2 0 Bacteriophage Mu Gam like protein ADIP PF11559.3 KFM01267.1 - 0.32 10.8 23.5 0.83 9.5 4.3 3.2 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding T2SM PF04612.7 KFM01267.1 - 0.58 9.9 0.1 0.58 9.9 0.0 2.7 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein M DUF730 PF05325.6 KFM01267.1 - 1 9.2 4.5 19 5.0 1.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF730) DUF342 PF03961.8 KFM01267.1 - 1.6 7.0 16.9 6.4 5.0 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF342) V-ATPase_G PF03179.10 KFM01267.1 - 1.8 8.9 9.6 4.3 7.6 3.0 2.6 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit Laminin_II PF06009.7 KFM01267.1 - 2.4 7.9 14.9 0.67 9.6 1.5 3.2 2 1 1 3 3 3 0 Laminin Domain II GLTSCR1 PF15249.1 KFM01267.1 - 2.6 8.1 6.9 2.6 8.2 1.9 2.5 2 1 0 2 2 2 0 Glioma tumor suppressor candidate region Tropomyosin_1 PF12718.2 KFM01267.1 - 3 7.6 25.5 3.9 7.3 3.8 4.1 1 1 3 4 4 4 0 Tropomyosin like IZUMO PF15005.1 KFM01267.1 - 3.8 7.5 9.7 0.59 10.1 1.6 2.5 2 1 1 3 3 2 0 Izumo sperm-egg fusion Kinetocho_Slk19 PF12709.2 KFM01267.1 - 3.8 7.6 21.1 0.45 10.6 3.0 4.6 2 2 1 4 4 4 0 Central kinetochore-associated KIF1B PF12423.3 KFM01267.1 - 3.9 7.5 6.3 2.3 8.3 1.7 2.7 3 1 0 3 3 2 0 Kinesin protein 1B DUF2265 PF10023.4 KFM01267.1 - 6.2 5.8 9.0 0.86 8.6 2.2 2.2 1 1 1 2 2 2 0 Predicted aminopeptidase (DUF2265) DUF972 PF06156.8 KFM01267.1 - 6.8 7.0 22.9 4.9 7.5 0.4 4.3 1 1 2 4 4 4 0 Protein of unknown function (DUF972) Phage_GP20 PF06810.6 KFM01267.1 - 9.1 5.6 17.7 1.8 7.9 1.6 3.2 1 1 2 3 3 3 0 Phage minor structural protein GP20 Filament PF00038.16 KFM01269.1 - 1.6e-102 343.2 22.6 1.8e-102 343.0 15.7 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 KFM01269.1 - 4.1e-05 23.3 0.2 4.1e-05 23.3 0.1 3.5 3 1 0 3 3 3 1 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 KFM01269.1 - 0.00016 21.5 30.7 0.00086 19.1 3.8 4.8 3 2 1 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Nsp1_C PF05064.8 KFM01269.1 - 0.0016 18.0 7.4 0.0016 18.0 5.1 3.5 2 2 1 3 3 3 1 Nsp1-like C-terminal region Kinetocho_Slk19 PF12709.2 KFM01269.1 - 0.0029 17.6 14.8 0.081 13.0 0.5 4.4 4 1 1 5 5 5 2 Central kinetochore-associated TBPIP PF07106.8 KFM01269.1 - 0.0069 15.9 6.7 0.0069 15.9 4.7 3.2 2 1 0 3 3 3 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Myosin_tail_1 PF01576.14 KFM01269.1 - 0.016 12.9 20.0 0.047 11.4 5.6 2.7 2 1 0 3 3 3 0 Myosin tail V_ATPase_I PF01496.14 KFM01269.1 - 0.02 12.7 9.7 0.026 12.3 6.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Baculo_PEP_C PF04513.7 KFM01269.1 - 0.029 14.2 13.1 1.2 8.9 1.6 3.4 2 1 1 4 4 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin_1 PF12718.2 KFM01269.1 - 0.048 13.5 22.3 1.4 8.7 7.9 3.4 3 0 0 3 3 3 0 Tropomyosin like DUF745 PF05335.8 KFM01269.1 - 0.084 12.3 8.0 1.6 8.1 4.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) ADIP PF11559.3 KFM01269.1 - 0.095 12.6 24.3 2 8.2 0.2 4.0 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding DUF4140 PF13600.1 KFM01269.1 - 0.16 12.4 12.6 8.5 6.8 1.1 4.2 3 1 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) Prefoldin_2 PF01920.15 KFM01269.1 - 0.22 11.2 22.1 3.3 7.5 1.6 4.9 4 1 2 6 6 5 0 Prefoldin subunit Transposase_22 PF02994.9 KFM01269.1 - 0.34 9.3 19.9 0.043 12.3 7.2 2.5 2 1 0 2 2 2 0 L1 transposable element DUF1664 PF07889.7 KFM01269.1 - 0.41 10.4 8.7 0.71 9.6 0.9 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) IncA PF04156.9 KFM01269.1 - 0.46 10.0 35.4 2.1 7.9 14.6 3.5 1 1 1 2 2 2 0 IncA protein IFT57 PF10498.4 KFM01269.1 - 0.46 9.1 17.4 0.69 8.5 6.5 2.8 2 1 1 3 3 3 0 Intra-flagellar transport protein 57 MscS_porin PF12795.2 KFM01269.1 - 0.46 9.7 19.2 1.5 8.0 10.2 3.0 3 1 0 3 3 3 0 Mechanosensitive ion channel porin domain BRE1 PF08647.6 KFM01269.1 - 0.49 10.4 11.4 0.59 10.1 1.4 3.4 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase DivIC PF04977.10 KFM01269.1 - 1.2 8.7 20.5 10 5.6 0.0 5.1 4 1 0 5 5 5 0 Septum formation initiator FlxA PF14282.1 KFM01269.1 - 1.4 8.9 19.8 1.6 8.6 8.3 3.6 3 1 0 3 3 3 0 FlxA-like protein DUF948 PF06103.6 KFM01269.1 - 2.3 8.1 7.0 7.5 6.4 0.7 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Bacillus_HBL PF05791.6 KFM01269.1 - 3 7.1 8.8 1.2 8.4 2.1 2.7 2 2 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) SlyX PF04102.7 KFM01269.1 - 3.3 8.1 19.1 0.69 10.3 1.8 4.3 3 1 1 4 4 4 0 SlyX Spc7 PF08317.6 KFM01269.1 - 3.6 6.1 24.2 0.021 13.5 3.6 3.6 1 1 4 5 5 5 0 Spc7 kinetochore protein FlaC_arch PF05377.6 KFM01269.1 - 3.8 7.4 16.7 0.38 10.6 0.2 4.6 4 1 0 5 5 4 0 Flagella accessory protein C (FlaC) HR1 PF02185.11 KFM01269.1 - 4.3 7.1 16.1 8.8 6.1 0.7 3.8 2 1 1 3 3 3 0 Hr1 repeat THP2 PF09432.5 KFM01269.1 - 7.1 6.5 10.3 7.1 6.4 0.1 3.3 2 1 1 3 3 3 0 Tho complex subunit THP2 TMF_DNA_bd PF12329.3 KFM01269.1 - 9.4 6.1 18.2 10 6.0 0.1 4.3 3 2 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Filament PF00038.16 KFM01270.1 - 3.7e-107 358.4 24.5 4.2e-107 358.2 17.0 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 KFM01270.1 - 5.2e-06 26.2 23.5 1.6e-05 24.6 0.6 2.9 3 1 0 3 3 3 2 TPR/MLP1/MLP2-like protein Nsp1_C PF05064.8 KFM01270.1 - 0.00098 18.7 8.0 0.00098 18.7 5.6 3.0 2 2 0 2 2 2 1 Nsp1-like C-terminal region CENP-F_leu_zip PF10473.4 KFM01270.1 - 0.0012 18.7 33.6 0.02 14.7 10.4 4.8 3 2 1 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.7 KFM01270.1 - 0.0023 17.7 4.3 0.012 15.4 0.3 2.7 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Kinetocho_Slk19 PF12709.2 KFM01270.1 - 0.0041 17.1 14.1 0.44 10.6 0.8 4.4 4 1 1 5 5 4 2 Central kinetochore-associated Myosin_tail_1 PF01576.14 KFM01270.1 - 0.005 14.6 23.2 0.011 13.5 7.6 2.2 2 1 0 2 2 2 2 Myosin tail Prefoldin_2 PF01920.15 KFM01270.1 - 0.02 14.6 21.1 3.9 7.2 2.7 4.8 4 1 0 4 4 4 0 Prefoldin subunit DUF4200 PF13863.1 KFM01270.1 - 0.071 13.0 0.5 0.071 13.0 0.4 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) HR1 PF02185.11 KFM01270.1 - 0.087 12.5 16.5 2.1 8.1 3.8 3.8 2 1 1 3 3 3 0 Hr1 repeat TMF_DNA_bd PF12329.3 KFM01270.1 - 0.094 12.5 13.3 0.073 12.8 3.3 3.6 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4140 PF13600.1 KFM01270.1 - 0.13 12.6 13.6 5 7.6 1.3 4.3 3 1 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) IncA PF04156.9 KFM01270.1 - 0.14 11.7 36.5 0.2 11.2 14.3 3.6 1 1 2 3 3 3 0 IncA protein Tropomyosin_1 PF12718.2 KFM01270.1 - 0.16 11.8 22.3 6.1 6.6 9.1 3.3 3 0 0 3 3 3 0 Tropomyosin like MADF_DNA_bdg PF10545.4 KFM01270.1 - 0.17 12.0 3.5 0.82 9.8 0.1 3.2 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like FlaC_arch PF05377.6 KFM01270.1 - 0.57 10.1 12.4 1.1 9.2 0.0 4.5 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) ADIP PF11559.3 KFM01270.1 - 0.6 10.0 28.1 0.57 10.0 1.0 4.0 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding TBPIP PF07106.8 KFM01270.1 - 0.64 9.5 20.6 0.039 13.5 5.8 3.0 2 2 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) SlyX PF04102.7 KFM01270.1 - 1.2 9.5 20.1 1.2 9.5 2.4 4.2 3 1 1 4 4 4 0 SlyX BLOC1_2 PF10046.4 KFM01270.1 - 1.2 9.2 17.2 0.26 11.4 2.3 4.1 3 2 2 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Bacillus_HBL PF05791.6 KFM01270.1 - 1.3 8.3 7.2 3.2 7.0 1.6 2.7 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) FlxA PF14282.1 KFM01270.1 - 2 8.3 21.9 0.27 11.2 7.2 3.7 2 2 1 3 3 3 0 FlxA-like protein MscS_porin PF12795.2 KFM01270.1 - 2.1 7.6 19.8 1.4 8.2 3.4 3.5 3 1 1 4 4 4 0 Mechanosensitive ion channel porin domain BRE1 PF08647.6 KFM01270.1 - 2.5 8.1 10.9 1.7 8.6 0.2 3.3 2 1 1 3 3 2 0 BRE1 E3 ubiquitin ligase Transposase_22 PF02994.9 KFM01270.1 - 3.2 6.1 19.1 0.62 8.4 7.9 2.1 2 0 0 2 2 2 0 L1 transposable element DivIC PF04977.10 KFM01270.1 - 4.7 6.7 21.4 5.4 6.5 0.1 4.9 5 0 0 5 5 5 0 Septum formation initiator Prefoldin PF02996.12 KFM01270.1 - 5.1 6.7 14.2 5.4 6.6 0.5 3.8 3 0 0 3 3 3 0 Prefoldin subunit Phage_GPO PF05929.6 KFM01270.1 - 5.1 6.2 8.5 2.5 7.2 2.0 2.2 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase V_ATPase_I PF01496.14 KFM01270.1 - 7.5 4.2 13.5 15 3.2 9.4 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.6 KFM01270.1 - 8.6 4.9 22.7 0.54 8.8 7.1 3.1 1 1 2 4 4 4 0 Spc7 kinetochore protein Filament PF00038.16 KFM01271.1 - 4e-118 394.4 22.3 4.9e-118 394.1 15.5 1.1 1 0 0 1 1 1 1 Intermediate filament protein Myosin_tail_1 PF01576.14 KFM01271.1 - 1.3e-05 23.1 20.5 8.8e-05 20.4 1.0 2.6 2 1 0 2 2 2 2 Myosin tail Transposase_22 PF02994.9 KFM01271.1 - 0.045 12.2 9.7 0.067 11.6 3.6 2.1 2 0 0 2 2 2 0 L1 transposable element DUF4618 PF15397.1 KFM01271.1 - 0.054 12.8 9.6 0.027 13.8 3.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4618) FlxA PF14282.1 KFM01271.1 - 0.16 11.9 11.6 3.2 7.7 4.1 3.1 2 1 1 3 3 3 0 FlxA-like protein HR1 PF02185.11 KFM01271.1 - 0.32 10.7 11.3 0.18 11.6 0.3 3.8 2 1 1 3 3 3 0 Hr1 repeat DUF1664 PF07889.7 KFM01271.1 - 0.34 10.7 12.3 0.18 11.5 0.7 3.6 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) Reo_sigmaC PF04582.7 KFM01271.1 - 0.38 9.8 3.3 1.6 7.7 1.0 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF342 PF03961.8 KFM01271.1 - 0.42 8.9 10.8 3.8 5.8 3.6 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF342) DivIC PF04977.10 KFM01271.1 - 0.65 9.5 17.8 1.4 8.4 0.1 4.7 5 0 0 5 5 5 0 Septum formation initiator Bacillus_HBL PF05791.6 KFM01271.1 - 0.68 9.2 8.1 0.74 9.1 2.6 2.5 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) FlaC_arch PF05377.6 KFM01271.1 - 1.2 9.0 7.9 31 4.5 0.0 4.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) ADIP PF11559.3 KFM01271.1 - 1.4 8.8 23.6 1.3 8.8 1.6 3.9 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 KFM01271.1 - 6.3 6.3 26.0 18 4.8 10.9 3.5 2 1 0 3 3 3 0 IncA protein COG2 PF06148.6 KFM01271.1 - 8.8 6.2 9.7 2.7 7.8 0.1 3.6 2 1 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Kinetocho_Slk19 PF12709.2 KFM01271.1 - 9 6.4 9.0 42 4.2 1.0 3.7 2 1 1 3 3 3 0 Central kinetochore-associated Lzipper-MIP1 PF14389.1 KFM01271.1 - 9.3 6.4 14.9 0.67 10.0 1.0 3.9 3 1 0 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 Milton PF12448.3 KFM01272.1 - 0.00042 20.5 0.0 0.00058 20.0 0.0 1.2 1 0 0 1 1 1 1 Kinesin associated protein Arm PF00514.18 KFM01273.1 - 5.4e-57 187.8 24.4 5.2e-10 38.7 0.0 12.3 13 0 0 13 13 13 7 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFM01273.1 - 7.3e-17 61.4 16.2 2.6e-06 27.6 0.9 5.9 4 2 2 6 6 6 6 HEAT repeats HEAT PF02985.17 KFM01273.1 - 7.5e-11 41.1 7.4 0.035 14.1 0.0 7.1 7 0 0 7 7 7 3 HEAT repeat Adaptin_N PF01602.15 KFM01273.1 - 2.5e-07 29.4 8.2 5.7e-05 21.6 1.0 2.9 2 1 0 2 2 2 2 Adaptin N terminal region V-ATPase_H_N PF03224.9 KFM01273.1 - 3.6e-07 29.6 1.4 0.052 12.6 0.1 3.7 1 1 1 3 3 3 3 V-ATPase subunit H Proteasom_PSMB PF10508.4 KFM01273.1 - 3e-05 22.4 6.3 0.0028 16.0 0.7 3.1 4 0 0 4 4 4 2 Proteasome non-ATPase 26S subunit RIX1 PF08167.7 KFM01273.1 - 5.1e-05 23.0 2.8 0.24 11.0 0.1 3.0 2 1 1 3 3 3 2 rRNA processing/ribosome biogenesis Arm_2 PF04826.8 KFM01273.1 - 9.4e-05 21.6 3.9 0.4 9.7 0.1 5.1 4 2 2 6 6 6 1 Armadillo-like HEAT_EZ PF13513.1 KFM01273.1 - 0.0004 20.7 14.2 2.2 8.8 0.1 6.6 6 2 1 7 7 6 2 HEAT-like repeat RasGEF_N_2 PF14663.1 KFM01273.1 - 0.002 18.0 5.8 13 5.7 0.0 5.3 4 1 2 6 6 6 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Cnd1 PF12717.2 KFM01273.1 - 0.023 14.5 2.0 0.4 10.4 0.1 3.5 4 2 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Atx10homo_assoc PF09759.4 KFM01273.1 - 0.072 12.8 3.6 0.38 10.5 0.1 3.7 5 0 0 5 5 5 0 Spinocerebellar ataxia type 10 protein domain FKBP_C PF00254.23 KFM01274.1 - 6.4e-63 208.7 0.0 1.3e-27 95.6 0.0 4.2 4 0 0 4 4 4 3 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_1 PF00036.27 KFM01274.1 - 3.1e-09 35.4 0.6 0.00067 18.7 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 KFM01274.1 - 7.7e-08 31.3 1.3 0.0021 17.3 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KFM01274.1 - 5e-06 25.9 0.2 0.19 11.7 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 KFM01274.1 - 5.9e-06 26.3 0.5 0.42 10.7 0.0 2.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 KFM01274.1 - 0.0043 16.6 0.5 0.041 13.5 0.1 2.3 1 1 1 2 2 2 1 EF-hand domain pair UMPH-1 PF05822.7 KFM01275.1 - 8.2e-119 395.3 0.3 9.6e-119 395.1 0.2 1.0 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.2 KFM01275.1 - 0.00054 20.1 0.0 0.00082 19.5 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 KFM01275.1 - 0.02 14.0 1.0 0.14 11.3 0.1 2.3 2 1 0 2 2 2 0 Putative Phosphatase HAD_2 PF13419.1 KFM01275.1 - 0.027 14.7 0.0 0.072 13.3 0.0 1.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase BACK PF07707.10 KFM01276.1 - 1.1e-28 99.0 3.0 8.1e-28 96.2 1.1 2.4 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_1 PF01344.20 KFM01276.1 - 1.3e-22 79.0 2.9 2.5e-06 26.9 0.0 5.6 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 KFM01276.1 - 4.9e-22 77.1 1.1 0.0001 22.2 0.0 4.9 3 1 2 5 5 5 4 Kelch motif BTB PF00651.26 KFM01276.1 - 1e-16 60.8 0.0 3.7e-16 59.0 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.1 KFM01276.1 - 2.2e-11 43.5 0.0 0.016 15.3 0.0 5.3 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.1 KFM01276.1 - 5.2e-09 35.7 0.0 3 7.6 0.0 5.5 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.10 KFM01276.1 - 2.5e-08 33.3 1.8 0.031 14.0 0.1 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 KFM01276.1 - 0.024 14.5 2.4 4.2 7.4 0.0 3.8 4 0 0 4 4 4 0 Kelch motif LVIVD PF08309.6 KFM01276.1 - 0.1 11.5 0.2 9.6 5.2 0.1 2.4 2 0 0 2 2 2 0 LVIVD repeat Citrate_synt PF00285.16 KFM01277.1 - 2.3e-22 79.2 0.0 3.8e-20 71.9 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase Ligase_CoA PF00549.14 KFM01277.1 - 1.9e-13 50.2 0.1 4.2e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.14 KFM01277.1 - 5.8e-10 39.5 0.0 1.4e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.5 KFM01277.1 - 2.8e-07 30.1 0.0 5.7e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.1 KFM01277.1 - 0.00026 20.5 0.0 0.0023 17.5 0.0 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_5 PF13549.1 KFM01277.1 - 0.19 10.9 0.0 0.34 10.1 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain TPR_12 PF13424.1 KFM01278.1 - 2e-15 56.4 11.0 2.6e-05 24.0 2.0 4.1 3 2 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 KFM01278.1 - 5.8e-15 54.6 7.2 0.0033 17.0 0.1 5.4 4 1 1 5 5 5 5 TPR repeat TPR_1 PF00515.23 KFM01278.1 - 7e-15 53.9 8.4 0.0062 16.1 0.0 6.2 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 KFM01278.1 - 5.5e-12 44.6 10.0 0.19 11.7 0.0 6.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 KFM01278.1 - 1.3e-10 40.2 9.9 0.19 11.6 0.0 7.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFM01278.1 - 2.7e-06 26.7 7.8 0.062 13.1 0.0 6.7 5 1 1 6 6 6 1 Tetratricopeptide repeat RPN7 PF10602.4 KFM01278.1 - 7.1e-05 22.2 4.7 0.00045 19.6 0.8 2.8 2 1 0 2 2 2 1 26S proteasome subunit RPN7 Apc3 PF12895.2 KFM01278.1 - 0.00017 21.6 6.8 0.013 15.6 0.2 4.1 2 2 2 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 KFM01278.1 - 0.00034 21.0 3.0 14 6.6 0.0 6.0 5 2 2 7 7 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 KFM01278.1 - 0.002 17.9 1.2 0.39 10.7 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFM01278.1 - 0.025 15.2 6.8 16 6.3 0.0 4.9 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 KFM01278.1 - 0.044 14.2 10.5 52 4.6 0.1 6.8 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 KFM01278.1 - 1.1 9.6 9.1 9.2 6.7 0.0 5.5 7 0 0 7 7 6 0 Tetratricopeptide repeat CNPase PF05881.7 KFM01279.1 - 1.9e-118 394.0 0.1 2.5e-118 393.6 0.1 1.2 1 0 0 1 1 1 1 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) AAA_17 PF13207.1 KFM01279.1 - 2.7e-08 34.6 0.0 4.8e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KFM01279.1 - 7.4e-07 28.4 0.1 8.5e-06 25.0 0.1 2.2 1 1 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 KFM01279.1 - 7.8e-06 25.8 0.0 1.5e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KFM01279.1 - 9.1e-06 25.8 0.8 0.00012 22.2 0.2 2.6 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KFM01279.1 - 2.5e-05 24.1 0.4 0.00036 20.4 0.1 2.2 1 1 1 2 2 2 1 AAA domain 6PF2K PF01591.13 KFM01279.1 - 4.6e-05 22.5 0.1 0.19 10.7 0.0 2.2 1 1 0 2 2 2 2 6-phosphofructo-2-kinase AAA_5 PF07728.9 KFM01279.1 - 0.00033 20.3 0.0 0.00056 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) CPT PF07931.7 KFM01279.1 - 0.0007 19.2 0.0 0.003 17.1 0.0 2.0 2 1 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_16 PF13191.1 KFM01279.1 - 0.00081 19.4 0.3 0.0048 16.8 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 KFM01279.1 - 0.00086 19.6 0.0 0.0015 18.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_18 PF13238.1 KFM01279.1 - 0.00093 19.5 0.0 0.002 18.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KFM01279.1 - 0.0011 17.8 0.6 0.055 12.3 0.4 2.3 1 1 0 1 1 1 1 NB-ARC domain AAA_19 PF13245.1 KFM01279.1 - 0.0023 17.6 0.0 0.004 16.8 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KFM01279.1 - 0.0023 17.5 0.0 0.03 13.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KFM01279.1 - 0.0034 17.5 0.0 0.0093 16.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 KFM01279.1 - 0.012 15.0 0.1 0.037 13.5 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain KAP_NTPase PF07693.9 KFM01279.1 - 0.021 13.8 0.0 0.029 13.3 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain NACHT PF05729.7 KFM01279.1 - 0.031 13.9 0.0 0.076 12.6 0.0 1.8 1 1 0 1 1 1 0 NACHT domain KTI12 PF08433.5 KFM01279.1 - 0.037 13.2 0.0 0.063 12.4 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RNA_helicase PF00910.17 KFM01279.1 - 0.038 14.1 0.0 0.11 12.6 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_23 PF13476.1 KFM01279.1 - 0.052 13.8 0.6 0.33 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain tRNA_lig_kinase PF08303.6 KFM01279.1 - 0.057 13.3 0.1 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 tRNA ligase kinase domain Viral_helicase1 PF01443.13 KFM01279.1 - 0.094 12.2 0.0 0.3 10.5 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase cobW PF02492.14 KFM01279.1 - 0.15 11.4 0.0 1.3 8.4 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TPR_11 PF13414.1 KFM01280.1 - 4.4e-52 173.6 26.6 1e-18 66.7 2.5 6.3 2 1 3 6 6 6 6 TPR repeat TPR_1 PF00515.23 KFM01280.1 - 3.2e-44 146.7 28.9 3.4e-07 29.6 2.4 9.1 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.12 KFM01280.1 - 1.2e-40 134.1 21.9 1.7e-06 27.5 1.0 9.5 9 0 0 9 9 9 7 Tetratricopeptide repeat DnaJ PF00226.26 KFM01280.1 - 9.2e-25 86.1 2.6 9.2e-25 86.1 1.8 2.8 3 0 0 3 3 2 1 DnaJ domain TPR_16 PF13432.1 KFM01280.1 - 1.7e-20 73.1 7.8 1e-05 26.0 0.4 6.2 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 KFM01280.1 - 4e-20 70.0 18.6 0.00085 18.9 0.3 8.6 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.1 KFM01280.1 - 4.4e-17 60.7 12.8 6.6e-05 22.8 0.1 8.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFM01280.1 - 3e-16 59.5 15.7 0.0045 17.2 0.1 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 KFM01280.1 - 1.2e-15 57.2 21.4 0.00016 21.5 0.3 6.7 1 1 7 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.1 KFM01280.1 - 7.6e-14 50.9 6.7 0.015 15.8 0.0 8.0 6 3 3 9 9 8 2 Tetratricopeptide repeat Apc3 PF12895.2 KFM01280.1 - 1.7e-11 44.0 27.2 0.00011 22.3 0.2 5.2 2 2 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KFM01280.1 - 1.1e-10 41.2 12.5 0.29 11.0 0.1 6.6 3 3 4 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFM01280.1 - 5.4e-08 32.0 11.4 0.45 10.4 0.3 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFM01280.1 - 4.1e-07 30.0 15.1 0.22 12.0 0.5 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_4 PF07721.9 KFM01280.1 - 0.0031 17.7 0.4 1.6 9.3 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.13 KFM01280.1 - 0.0047 16.7 16.9 0.21 11.4 0.4 5.1 3 2 0 3 3 3 2 MIT (microtubule interacting and transport) domain Rapsyn_N PF10579.4 KFM01280.1 - 0.056 13.2 0.3 17 5.2 0.0 3.7 3 0 0 3 3 3 0 Rapsyn N-terminal myristoylation and linker region TPR_10 PF13374.1 KFM01280.1 - 0.12 12.4 9.9 26 4.8 0.3 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KFM01280.1 - 0.15 11.9 12.0 17 5.3 0.1 5.9 7 0 0 7 7 5 0 Fis1 C-terminal tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 KFM01280.1 - 0.22 11.7 10.4 5.3 7.2 0.1 4.6 4 1 1 5 5 5 0 Alkyl sulfatase dimerisation TOM20_plant PF06552.7 KFM01280.1 - 0.32 10.5 7.1 3.8 7.0 0.1 3.6 3 1 1 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 Sel1 PF08238.7 KFM01280.1 - 1.9 9.2 6.3 4.9 7.9 0.7 3.5 3 0 0 3 3 3 0 Sel1 repeat SHNi-TPR PF10516.4 KFM01280.1 - 4.8 6.5 9.9 5.9 6.2 0.1 5.2 6 0 0 6 6 6 0 SHNi-TPR Ras PF00071.17 KFM01281.1 - 3.6e-25 88.2 0.2 4.2e-25 88.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM01281.1 - 1.8e-19 70.3 0.2 3e-19 69.6 0.1 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM01281.1 - 1.5e-07 30.8 0.1 1.9e-07 30.4 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFM01281.1 - 8.1e-06 25.4 0.1 0.00046 19.6 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFM01281.1 - 0.00012 22.0 0.0 0.00016 21.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KFM01281.1 - 0.00018 21.3 0.5 0.00054 19.8 0.3 1.8 1 1 0 1 1 1 1 Dynamin family DUF2121 PF09894.4 KFM01281.1 - 0.0047 16.2 0.1 0.071 12.3 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2121) G-alpha PF00503.15 KFM01281.1 - 0.006 15.3 0.4 0.074 11.7 0.3 1.9 1 1 0 1 1 1 1 G-protein alpha subunit SpoIIP PF07454.6 KFM01281.1 - 0.067 12.3 0.0 0.076 12.1 0.0 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) AAA_17 PF13207.1 KFM01281.1 - 0.085 13.6 0.2 0.13 13.0 0.2 1.5 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.5 KFM01281.1 - 0.11 11.7 0.6 0.39 9.9 0.4 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit zf-met PF12874.2 KFM01282.1 - 7.7e-30 102.1 27.9 7.3e-08 32.3 0.3 5.1 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFM01282.1 - 1.3e-24 85.6 26.5 6.1e-08 32.5 1.7 5.2 4 1 1 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFM01282.1 - 1.2e-08 35.0 21.5 0.0029 17.6 0.2 4.3 4 0 0 4 4 4 4 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.7 KFM01282.1 - 2.5e-07 30.6 7.8 0.036 13.8 0.1 4.2 4 0 0 4 4 4 3 A-kinase anchoring protein 95 (AKAP95) zf-U1 PF06220.7 KFM01282.1 - 7.1e-06 25.4 14.6 0.088 12.3 0.0 4.4 4 0 0 4 4 4 3 U1 zinc finger zf-DHHC PF01529.15 KFM01282.1 - 0.028 13.8 0.6 3.2 7.0 0.0 2.5 2 0 0 2 2 2 0 DHHC palmitoyltransferase zf-C2H2_4 PF13894.1 KFM01282.1 - 0.3 11.5 19.5 1.2 9.5 1.1 4.8 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KFM01282.1 - 0.78 10.2 22.6 4.1 7.9 1.0 4.9 5 1 1 6 6 6 0 Zinc finger, C2H2 type Cas_CXXC_CXXC PF09706.5 KFM01282.1 - 3.3 7.9 6.2 19 5.4 0.1 4.0 4 0 0 4 4 4 0 CRISPR-associated protein (Cas_CXXC_CXXC) RIG-I_C-RD PF11648.3 KFM01283.1 - 4.7e-41 139.5 3.7 9.9e-41 138.4 2.5 1.6 1 0 0 1 1 1 1 C-terminal domain of RIG-I Helicase_C PF00271.26 KFM01283.1 - 1e-16 60.5 0.1 2.6e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFM01283.1 - 5e-07 29.3 0.7 2.3e-06 27.2 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 KFM01283.1 - 8.2e-07 29.0 0.4 2e-06 27.7 0.1 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KFM01283.1 - 2.1e-05 23.4 0.2 4.8e-05 22.2 0.1 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain AAA_11 PF13086.1 KFM01283.1 - 0.097 12.2 1.8 0.16 11.5 0.4 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KFM01283.1 - 0.23 11.6 2.4 1.6 8.8 0.1 3.0 3 1 0 3 3 3 0 AAA domain PCAF_N PF06466.6 KFM01284.1 - 2.7e-134 446.2 1.5 3.8e-134 445.8 1.0 1.2 1 0 0 1 1 1 1 PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain PF00439.20 KFM01284.1 - 4.2e-25 87.4 0.4 1e-24 86.2 0.3 1.7 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 KFM01284.1 - 2.2e-06 27.7 0.2 6.7e-06 26.1 0.1 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFM01284.1 - 0.0006 19.7 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KFM01284.1 - 0.049 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HSP20 PF00011.16 KFM01285.1 - 3.9e-13 49.1 0.0 5.6e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family IFT57 PF10498.4 KFM01285.1 - 0.089 11.5 0.3 0.31 9.7 0.0 1.7 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Alpha_TIF PF02232.10 KFM01285.1 - 0.11 11.2 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Alpha trans-inducing protein (Alpha-TIF) HSP20 PF00011.16 KFM01286.1 - 4.7e-17 61.7 0.0 6.3e-17 61.3 0.0 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Ras PF00071.17 KFM01287.1 - 1.4e-61 206.5 0.5 1.7e-61 206.3 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM01287.1 - 7.1e-20 71.6 0.1 1.3e-19 70.8 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFM01287.1 - 4e-12 45.7 0.1 5e-12 45.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFM01287.1 - 2.1e-05 23.7 0.0 2.6e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFM01287.1 - 9.8e-05 22.2 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFM01287.1 - 0.00015 21.2 0.1 0.00038 19.9 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KFM01287.1 - 0.073 12.2 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SRPRB PF09439.5 KFM01287.1 - 0.086 12.0 0.1 0.3 10.3 0.0 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Orexin PF02072.10 KFM01288.1 - 8.2e-55 184.1 8.5 1e-54 183.7 5.9 1.1 1 0 0 1 1 1 1 Prepro-orexin DUF350 PF03994.9 KFM01288.1 - 0.11 12.2 0.1 15 5.4 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF350) PI-PLC-Y PF00387.14 KFM01289.1 - 1.2e-43 147.7 0.1 2.6e-43 146.7 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain PI-PLC-X PF00388.14 KFM01289.1 - 7.5e-40 135.6 0.0 1.3e-39 134.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain EF-hand_like PF09279.6 KFM01289.1 - 6e-25 87.0 0.0 1.2e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 KFM01289.1 - 8.4e-15 54.3 0.0 3.2e-14 52.5 0.0 2.0 2 0 0 2 2 2 1 C2 domain PH PF00169.24 KFM01289.1 - 0.00013 22.0 0.0 0.00026 21.1 0.0 1.5 1 0 0 1 1 1 1 PH domain Mcp5_PH PF12814.2 KFM01289.1 - 0.0048 16.8 0.0 0.0084 16.0 0.0 1.4 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology GH3 PF03321.8 KFM01290.1 - 1.2e-32 113.1 0.0 1.3e-32 113.0 0.0 1.0 1 0 0 1 1 1 1 GH3 auxin-responsive promoter STAT_bind PF02864.10 KFM01291.1 - 1.3e-98 329.5 3.7 2.7e-98 328.6 2.6 1.5 1 0 0 1 1 1 1 STAT protein, DNA binding domain STAT_alpha PF01017.15 KFM01291.1 - 8.8e-55 185.2 22.3 2.1e-54 184.0 15.5 1.6 1 0 0 1 1 1 1 STAT protein, all-alpha domain STAT_int PF02865.12 KFM01291.1 - 3.7e-43 146.4 4.3 3.7e-43 146.4 2.9 3.2 3 1 1 4 4 4 1 STAT protein, protein interaction domain SH2 PF00017.19 KFM01291.1 - 5e-12 45.4 0.7 2.1e-10 40.2 0.0 3.1 3 0 0 3 3 3 1 SH2 domain STAT_bind PF02864.10 KFM01292.1 - 3.6e-128 426.4 0.4 2.9e-127 423.4 0.2 2.2 2 0 0 2 2 2 1 STAT protein, DNA binding domain STAT_alpha PF01017.15 KFM01292.1 - 1.6e-58 197.3 18.1 3e-58 196.5 12.5 1.4 1 0 0 1 1 1 1 STAT protein, all-alpha domain STAT_int PF02865.12 KFM01292.1 - 8.1e-42 142.1 8.1 8.1e-42 142.1 5.6 2.8 2 1 2 4 4 4 1 STAT protein, protein interaction domain SH2 PF00017.19 KFM01292.1 - 9e-14 51.0 0.0 2.4e-13 49.6 0.0 1.8 1 0 0 1 1 1 1 SH2 domain Syntaxin-6_N PF09177.6 KFM01292.1 - 0.0037 17.6 0.9 0.0037 17.6 0.6 2.9 2 1 1 3 3 3 1 Syntaxin 6, N-terminal Tropomyosin_1 PF12718.2 KFM01292.1 - 0.55 10.0 9.9 0.24 11.2 4.0 2.1 2 0 0 2 2 2 0 Tropomyosin like Fib_alpha PF08702.5 KFM01292.1 - 0.63 10.1 13.6 0.24 11.5 6.0 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family eIF3_N PF09440.5 KFM01292.1 - 0.76 9.9 11.0 4.9 7.3 1.3 3.2 3 0 0 3 3 3 0 eIF3 subunit 6 N terminal domain MerR-DNA-bind PF09278.6 KFM01292.1 - 1.4 9.3 14.0 1.6 9.1 0.3 4.0 4 0 0 4 4 4 0 MerR, DNA binding DUF342 PF03961.8 KFM01292.1 - 4.5 5.5 8.0 0.41 9.0 2.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF342) PTRF_SDPR PF15237.1 KFM01293.1 - 2.8e-102 341.3 35.0 7.2e-101 336.7 24.3 2.1 1 1 0 1 1 1 1 PTRF/SDPR family Reo_sigmaC PF04582.7 KFM01293.1 - 0.013 14.6 1.0 0.013 14.6 0.7 1.5 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Sec8_exocyst PF04048.9 KFM01293.1 - 0.051 13.2 12.2 0.025 14.2 3.0 2.4 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF1664 PF07889.7 KFM01293.1 - 0.086 12.6 16.7 0.76 9.5 4.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Laminin_II PF06009.7 KFM01293.1 - 0.21 11.3 15.5 0.38 10.5 5.2 2.4 2 0 0 2 2 2 0 Laminin Domain II Baculo_PEP_C PF04513.7 KFM01293.1 - 0.24 11.2 11.0 0.38 10.5 4.5 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ADIP PF11559.3 KFM01293.1 - 0.33 10.8 21.2 1.3 8.9 6.0 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding YjcZ PF13990.1 KFM01293.1 - 2.3 7.2 10.9 1.6 7.8 2.4 2.2 2 0 0 2 2 2 0 YjcZ-like protein Fib_alpha PF08702.5 KFM01293.1 - 4.9 7.2 19.1 0.67 10.0 4.4 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Nup54 PF13874.1 KFM01293.1 - 8.5 6.0 15.1 0.58 9.8 3.9 2.5 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 COG5 PF10392.4 KFM01293.1 - 9.4 6.1 12.5 8.4 6.3 3.6 2.3 2 0 0 2 2 2 0 Golgi transport complex subunit 5 V_ATPase_I PF01496.14 KFM01294.1 - 0 1070.8 0.5 0 1070.6 0.3 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family NAGLU PF05089.7 KFM01295.1 - 6e-142 472.3 2.7 7.6e-142 471.9 1.9 1.1 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.2 KFM01295.1 - 1.3e-86 290.3 0.0 1.7e-86 289.9 0.0 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain adh_short PF00106.20 KFM01296.1 - 1e-31 110.0 0.3 1.4e-31 109.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFM01296.1 - 2e-13 50.3 0.1 2.6e-13 50.0 0.1 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFM01296.1 - 5.6e-11 42.6 0.0 7.3e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KFM01296.1 - 6.9e-06 25.4 0.0 9.8e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KFM01296.1 - 0.00017 21.6 0.1 0.00028 20.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KFM01296.1 - 0.0054 16.4 0.1 0.012 15.3 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KFM01296.1 - 0.084 12.2 0.0 0.21 10.9 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KFM01296.1 - 0.11 11.7 0.0 0.71 9.0 0.0 1.9 2 0 0 2 2 2 0 NmrA-like family CoaE PF01121.15 KFM01297.1 - 1.8e-46 157.7 0.1 2.4e-46 157.4 0.1 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.1 KFM01297.1 - 7.6e-05 22.6 0.3 0.0011 18.8 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFM01297.1 - 0.00011 22.9 0.8 0.00068 20.4 0.5 2.1 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 KFM01297.1 - 0.00042 20.2 1.1 0.0016 18.3 0.8 1.8 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_18 PF13238.1 KFM01297.1 - 0.0014 18.9 3.6 0.013 15.7 2.5 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFM01297.1 - 0.0033 17.1 0.4 0.017 14.8 0.1 2.1 2 0 0 2 2 2 1 Part of AAA domain Zeta_toxin PF06414.7 KFM01297.1 - 0.0099 14.9 1.3 0.04 13.0 0.0 2.3 2 1 0 2 2 2 1 Zeta toxin KAP_NTPase PF07693.9 KFM01297.1 - 0.012 14.6 0.0 0.016 14.2 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain AAA_28 PF13521.1 KFM01297.1 - 0.013 15.4 7.5 0.34 10.8 5.2 2.8 1 1 0 1 1 1 0 AAA domain Pox_A32 PF04665.7 KFM01297.1 - 0.064 12.5 0.0 0.82 8.9 0.0 2.0 2 0 0 2 2 2 0 Poxvirus A32 protein ANTAR PF03861.9 KFM01297.1 - 0.085 12.4 1.1 2.7 7.6 0.1 2.5 2 0 0 2 2 2 0 ANTAR domain HLH PF00010.21 KFM01298.1 - 1.1e-15 56.9 0.1 3e-15 55.6 0.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TBPIP PF07106.8 KFM01299.1 - 1.6e-16 60.3 2.6 1.9e-16 60.0 1.8 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) BRCT_assoc PF12820.2 KFM01299.1 - 0.034 13.9 0.4 0.04 13.6 0.3 1.2 1 0 0 1 1 1 0 Serine-rich domain associated with BRCT Fe_bilin_red PF05996.7 KFM01299.1 - 0.052 13.0 0.3 0.055 12.9 0.2 1.1 1 0 0 1 1 1 0 Ferredoxin-dependent bilin reductase IFT20 PF14931.1 KFM01299.1 - 0.056 13.3 1.3 0.2 11.5 0.9 1.9 1 1 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 FlxA PF14282.1 KFM01299.1 - 0.066 13.1 0.2 0.097 12.6 0.1 1.2 1 0 0 1 1 1 0 FlxA-like protein DUF342 PF03961.8 KFM01299.1 - 0.068 11.5 1.3 0.077 11.4 0.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Scaffolding_pro PF11418.3 KFM01299.1 - 0.1 12.9 0.5 0.14 12.5 0.3 1.3 1 1 0 1 1 1 0 Phi29 scaffolding protein DUF3810 PF12725.2 KFM01299.1 - 0.14 11.0 0.6 0.17 10.7 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) MSG PF02349.10 KFM01299.1 - 0.26 11.2 4.7 0.32 10.9 3.3 1.1 1 0 0 1 1 1 0 Major surface glycoprotein Reticulon PF02453.12 KFM01300.1 - 0.02 14.5 0.3 0.02 14.5 0.2 1.7 2 0 0 2 2 2 0 Reticulon Tubulin PF00091.20 KFM01301.1 - 3.7e-58 196.8 0.0 7.2e-58 195.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFM01301.1 - 5.3e-48 162.2 0.1 9.8e-48 161.3 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain FERM_M PF00373.13 KFM01302.1 - 2.3e-05 24.5 0.0 3.3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 FERM central domain ACBP PF00887.14 KFM01302.1 - 0.0093 15.6 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein MyTH4 PF00784.12 KFM01303.1 - 1.9e-23 82.5 0.0 3.3e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 MyTH4 domain RA PF00788.18 KFM01303.1 - 1.9e-07 31.4 0.0 3.8e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SET PF00856.23 KFM01304.1 - 6.1e-23 81.9 0.3 3.4e-22 79.4 0.2 2.4 1 1 0 1 1 1 1 SET domain EZH2_WD-Binding PF11616.3 KFM01304.1 - 5.3e-16 58.1 0.1 1.2e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 WD repeat binding protein EZH2 RAMP PF04901.8 KFM01305.1 - 3.1e-42 142.9 1.0 3.5e-42 142.7 0.7 1.0 1 0 0 1 1 1 1 Receptor activity modifying family SusD-like_2 PF12771.2 KFM01305.1 - 0.11 10.8 0.0 0.12 10.7 0.0 1.1 1 0 0 1 1 1 0 Starch-binding associating with outer membrane ESCRT-II PF05871.7 KFM01306.1 - 1.2e-24 86.8 0.5 1.7e-24 86.3 0.2 1.4 2 0 0 2 2 2 1 ESCRT-II complex subunit Vps39_1 PF10366.4 KFM01306.1 - 0.11 12.5 0.1 0.12 12.3 0.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 Cyclin_N PF00134.18 KFM01307.1 - 2.6e-09 36.6 2.4 0.00038 20.0 0.2 2.8 3 0 0 3 3 3 2 Cyclin, N-terminal domain PA28_beta PF02252.13 KFM01308.1 - 4.1e-69 230.8 2.6 5.3e-69 230.4 1.8 1.1 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.13 KFM01308.1 - 2.8e-28 97.8 1.4 5.4e-28 96.9 1.0 1.5 1 0 0 1 1 1 1 Proteasome activator pa28 alpha subunit DUF4420 PF14390.1 KFM01308.1 - 0.057 12.2 0.1 0.1 11.4 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4420) GnsAB PF08178.6 KFM01308.1 - 0.18 11.4 1.3 0.47 10.1 0.0 2.3 3 0 0 3 3 3 0 GnsA/GnsB family Cu_amine_oxid PF01179.15 KFM01309.1 - 3.5e-42 144.5 2.7 5.5e-36 124.1 0.3 2.1 1 1 1 2 2 2 2 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KFM01309.1 - 6.1e-14 51.9 0.0 1.2e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KFM01309.1 - 1.6e-11 44.1 0.0 3.5e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DUF1965 PF09248.5 KFM01309.1 - 0.00057 19.7 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxid PF01179.15 KFM01310.1 - 2.7e-125 418.3 0.1 3.5e-125 417.9 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KFM01310.1 - 4.2e-14 52.4 0.0 8.7e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KFM01310.1 - 4.7e-11 42.6 0.0 1.2e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DUF1965 PF09248.5 KFM01310.1 - 0.00077 19.3 0.0 0.0026 17.6 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxid PF01179.15 KFM01311.1 - 1.9e-126 422.1 0.0 2.4e-126 421.8 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KFM01311.1 - 1.4e-12 47.4 0.0 2.8e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KFM01311.1 - 3.3e-11 43.1 0.0 6.9e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DUF1965 PF09248.5 KFM01311.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1965) PAP2 PF01569.16 KFM01312.1 - 3.5e-16 59.0 5.0 3.5e-16 59.0 3.5 2.2 2 1 0 2 2 2 1 PAP2 superfamily tRNA_SAD PF07973.9 KFM01313.1 - 3.9e-10 39.4 0.2 8.4e-10 38.3 0.1 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain CS PF04969.11 KFM01313.1 - 3.9e-05 24.0 0.1 7.9e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 CS domain Nod_GRP PF07806.6 KFM01313.1 - 0.099 12.2 2.3 0.23 11.0 1.6 1.5 1 0 0 1 1 1 0 Nodule-specific GRP repeat RUN PF02759.14 KFM01314.1 - 1.2e-31 109.1 0.0 2.1e-31 108.4 0.0 1.4 1 0 0 1 1 1 1 RUN domain Ribosomal_L27e PF01777.13 KFM01315.1 - 4e-39 132.6 7.7 4.5e-39 132.4 5.3 1.0 1 0 0 1 1 1 1 Ribosomal L27e protein family Bud13 PF09736.4 KFM01315.1 - 0.058 13.6 0.3 0.064 13.5 0.2 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex NID PF07292.8 KFM01316.1 - 2.1e-39 133.4 0.1 2.6e-23 81.8 0.1 2.5 2 1 0 2 2 2 2 Nmi/IFP 35 domain (NID) RRM_6 PF14259.1 KFM01316.1 - 0.016 15.1 0.0 2 8.4 0.0 2.7 3 0 0 3 3 3 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.17 KFM01318.1 - 1.1e-18 67.1 0.0 1.7e-18 66.4 0.0 1.3 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KFM01318.1 - 0.00021 21.7 0.0 0.0012 19.3 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein BRCT_assoc PF12820.2 KFM01319.1 - 1.7e-30 105.9 8.3 1.7e-30 105.9 5.7 3.9 3 1 0 3 3 3 1 Serine-rich domain associated with BRCT BRCT PF00533.21 KFM01319.1 - 2.2e-17 62.9 1.2 4.7e-09 36.2 0.0 3.1 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain zf-C3HC4_4 PF15227.1 KFM01319.1 - 6.5e-07 29.1 3.0 3e-06 27.0 2.1 2.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KFM01319.1 - 3.1e-06 26.7 2.7 3.1e-06 26.7 1.8 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM01319.1 - 9e-06 25.4 2.0 9e-06 25.4 1.4 2.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFM01319.1 - 9e-05 22.4 3.2 9e-05 22.4 2.2 3.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFM01319.1 - 0.00084 19.0 2.1 0.0046 16.6 1.5 2.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 KFM01319.1 - 0.0022 17.6 3.4 0.0022 17.6 2.4 3.0 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_6 PF14835.1 KFM01319.1 - 0.081 12.7 0.1 0.081 12.7 0.1 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-Nse PF11789.3 KFM01319.1 - 0.73 9.3 8.3 0.067 12.7 2.0 2.2 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit PB1 PF00564.19 KFM01320.1 - 1.8e-11 43.5 0.3 3.6e-11 42.5 0.2 1.6 1 0 0 1 1 1 1 PB1 domain ZZ PF00569.12 KFM01320.1 - 8.2e-05 22.0 8.2 0.00022 20.6 5.7 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type UBA PF00627.26 KFM01320.1 - 0.00024 20.8 0.0 0.00048 19.8 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain DUF1356 PF07092.7 KFM01321.1 - 3.8e-87 291.4 3.9 4.1e-87 291.3 2.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) DnaJ_CXXCXGXG PF00684.14 KFM01321.1 - 0.086 12.9 1.8 0.15 12.1 0.2 2.1 2 0 0 2 2 2 0 DnaJ central domain ETS_PEA3_N PF04621.8 KFM01322.1 - 1.9e-92 310.1 25.2 2.3e-91 306.5 17.5 2.0 1 1 0 1 1 1 1 PEA3 subfamily ETS-domain transcription factor N terminal domain Ets PF00178.17 KFM01322.1 - 5.7e-38 128.9 0.2 1e-37 128.1 0.1 1.4 1 0 0 1 1 1 1 Ets-domain Homeobox PF00046.24 KFM01323.1 - 3.2e-23 81.0 7.7 5.2e-23 80.4 5.4 1.3 1 0 0 1 1 1 1 Homeobox domain PP_M1 PF03012.9 KFM01323.1 - 0.036 13.4 3.5 0.054 12.8 2.4 1.3 1 0 0 1 1 1 0 Phosphoprotein TraG-D_C PF12696.2 KFM01323.1 - 0.73 9.7 4.4 1.1 9.1 3.0 1.3 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG Sclerostin PF05463.6 KFM01324.1 - 1.2e-75 253.3 6.8 1.3e-75 253.2 4.7 1.0 1 0 0 1 1 1 1 Sclerostin (SOST) DAN PF03045.10 KFM01324.1 - 5.3e-09 35.5 2.8 8.9e-09 34.8 2.0 1.4 1 0 0 1 1 1 1 DAN domain Cys_knot PF00007.17 KFM01324.1 - 1.2e-05 25.3 4.4 1.2e-05 25.3 3.0 1.6 2 0 0 2 2 2 1 Cystine-knot domain ET PF01684.11 KFM01324.1 - 0.022 14.7 0.5 0.052 13.5 0.3 1.7 1 1 0 1 1 1 0 ET module DSPc PF00782.15 KFM01325.1 - 2.3e-33 114.5 0.1 2.8e-33 114.3 0.1 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFM01325.1 - 7.2e-06 25.5 0.0 8.6e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KFM01325.1 - 0.00024 21.1 0.0 0.00031 20.8 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Init_tRNA_PT PF04179.7 KFM01325.1 - 0.00044 19.2 0.0 0.00044 19.2 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase DUF442 PF04273.8 KFM01325.1 - 0.014 15.2 0.0 0.026 14.3 0.0 1.6 1 1 0 1 1 1 0 Putative phosphatase (DUF442) SNase PF00565.12 KFM01325.1 - 0.041 14.1 0.1 0.17 12.1 0.1 1.9 1 1 0 1 1 1 0 Staphylococcal nuclease homologue Ras PF00071.17 KFM01326.1 - 1.7e-57 193.3 0.0 6.6e-57 191.4 0.0 1.7 2 0 0 2 2 2 1 Ras family Miro PF08477.8 KFM01326.1 - 5.1e-18 65.6 0.0 7.5e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM01326.1 - 2.7e-17 62.5 0.0 3.3e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFM01326.1 - 9.3e-06 24.9 0.0 1.4e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFM01326.1 - 5.2e-05 23.1 0.0 0.0011 18.8 0.0 2.1 1 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFM01326.1 - 0.0011 18.3 0.0 0.0036 16.7 0.0 1.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KFM01326.1 - 0.049 12.8 0.0 0.094 11.9 0.0 1.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 KFM01326.1 - 0.077 12.9 0.1 0.42 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Guanylate_kin PF00625.16 KFM01327.1 - 6.4e-42 143.0 1.4 1e-41 142.4 1.0 1.3 1 0 0 1 1 1 1 Guanylate kinase L27 PF02828.11 KFM01327.1 - 1.9e-24 85.1 4.3 5.8e-13 48.3 0.3 2.7 2 0 0 2 2 2 2 L27 domain PDZ PF00595.19 KFM01327.1 - 4.4e-12 46.0 0.8 8.9e-12 45.0 0.6 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM01327.1 - 2.6e-05 24.0 0.1 6.9e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 PDZ domain SH3_1 PF00018.23 KFM01327.1 - 0.0024 17.1 0.0 0.0061 15.9 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFM01327.1 - 0.11 12.0 0.0 0.28 10.7 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain IRK PF01007.15 KFM01328.1 - 2.8e-155 516.2 0.0 3.1e-155 516.0 0.0 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 KFM01328.1 - 0.0012 18.5 2.8 0.0028 17.3 2.0 1.7 1 1 0 1 1 1 1 Ion channel DUF3311 PF11755.3 KFM01328.1 - 0.013 14.9 1.4 0.025 14.1 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3311) I-set PF07679.11 KFM01329.1 - 1.2e-77 255.8 0.0 1.7e-14 53.4 0.0 6.7 6 0 0 6 6 6 6 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM01329.1 - 5.5e-61 202.6 7.3 4.7e-10 39.4 0.0 7.5 7 0 0 7 7 7 6 Immunoglobulin domain Ig_3 PF13927.1 KFM01329.1 - 5.5e-42 142.0 20.4 1e-08 35.5 0.0 8.2 8 1 0 8 8 8 6 Immunoglobulin domain ig PF00047.20 KFM01329.1 - 1.5e-37 127.5 3.1 1.7e-07 31.2 0.0 7.4 6 1 0 6 6 6 6 Immunoglobulin domain fn3 PF00041.16 KFM01329.1 - 5.7e-37 125.7 17.7 7.9e-14 51.5 1.4 4.7 4 0 0 4 4 4 4 Fibronectin type III domain V-set PF07686.12 KFM01329.1 - 1.5e-32 111.8 11.8 8.7e-07 28.8 0.0 8.9 8 2 1 9 9 8 5 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM01329.1 - 2.5e-08 33.6 0.9 0.048 13.5 0.0 5.3 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain Sp38 PF07354.7 KFM01329.1 - 4.4e-06 25.5 0.2 0.2 10.2 0.0 4.1 4 0 0 4 4 4 1 Zona-pellucida-binding protein (Sp38) Tissue_fac PF01108.12 KFM01329.1 - 5.3e-05 22.9 4.2 0.012 15.2 0.2 3.2 2 1 1 3 3 3 2 Tissue factor Interfer-bind PF09294.5 KFM01329.1 - 0.00025 21.0 1.1 4.1 7.4 0.0 3.9 4 0 0 4 4 4 2 Interferon-alpha/beta receptor, fibronectin type III C2-set PF05790.10 KFM01329.1 - 0.00075 19.4 0.1 25 4.9 0.0 5.3 5 1 1 6 6 6 0 Immunoglobulin C2-set domain Herpes_gE PF02480.11 KFM01329.1 - 0.0028 16.0 0.4 4.1 5.5 0.0 4.2 4 1 1 5 5 5 1 Alphaherpesvirus glycoprotein E V-set_CD47 PF08204.6 KFM01329.1 - 0.02 14.6 8.1 12 5.6 0.1 5.3 4 1 1 5 5 5 0 CD47 immunoglobulin-like domain I-set PF07679.11 KFM01330.1 - 3.7e-79 260.6 0.0 1.4e-15 56.8 0.0 6.7 6 0 0 6 6 6 6 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM01330.1 - 2.9e-61 203.5 0.1 1.3e-09 38.0 0.0 6.6 6 0 0 6 6 6 6 Immunoglobulin domain Ig_3 PF13927.1 KFM01330.1 - 3.7e-47 158.6 11.4 2.4e-08 34.3 0.0 8.2 10 0 0 10 10 10 6 Immunoglobulin domain ig PF00047.20 KFM01330.1 - 1.5e-42 143.5 0.1 1.1e-08 35.0 0.0 6.9 6 0 0 6 6 6 6 Immunoglobulin domain fn3 PF00041.16 KFM01330.1 - 1.4e-41 140.4 13.0 3.4e-15 55.9 0.1 4.5 4 0 0 4 4 4 4 Fibronectin type III domain V-set PF07686.12 KFM01330.1 - 1.3e-36 124.9 0.9 1.2e-08 34.7 0.0 8.0 4 3 2 6 6 6 6 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM01330.1 - 6.8e-08 32.3 1.4 0.51 10.2 0.0 5.0 5 0 0 5 5 5 3 CD80-like C2-set immunoglobulin domain Sp38 PF07354.7 KFM01330.1 - 1.8e-05 23.5 0.0 0.045 12.4 0.0 4.4 5 0 0 5 5 5 1 Zona-pellucida-binding protein (Sp38) V-set_CD47 PF08204.6 KFM01330.1 - 0.00013 21.7 1.6 11 5.8 0.0 4.8 4 1 0 4 4 4 2 CD47 immunoglobulin-like domain Tissue_fac PF01108.12 KFM01330.1 - 0.00039 20.1 2.4 0.11 12.2 0.1 3.2 2 1 1 3 3 3 1 Tissue factor DUF3688 PF12461.3 KFM01330.1 - 0.0017 18.6 0.7 0.99 9.8 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF3688) Herpes_gE PF02480.11 KFM01330.1 - 0.0056 15.0 0.1 12 4.0 0.0 4.3 6 0 0 6 6 6 1 Alphaherpesvirus glycoprotein E IL6Ra-bind PF09240.5 KFM01331.1 - 1.7e-23 82.6 0.4 5.5e-23 81.0 0.2 1.9 2 0 0 2 2 2 1 Interleukin-6 receptor alpha chain, binding Tissue_fac PF01108.12 KFM01331.1 - 1.9e-05 24.3 6.5 0.012 15.3 0.2 3.4 3 1 0 3 3 3 2 Tissue factor EpoR_lig-bind PF09067.5 KFM01331.1 - 0.017 15.0 0.9 0.038 13.9 0.2 1.9 2 0 0 2 2 2 0 Erythropoietin receptor, ligand binding fn3 PF00041.16 KFM01331.1 - 0.021 14.9 2.6 0.51 10.4 0.1 2.8 3 0 0 3 3 3 0 Fibronectin type III domain PolyA_pol PF01743.15 KFM01332.1 - 6.5e-32 110.4 0.3 1.1e-31 109.6 0.2 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 KFM01332.1 - 4.9e-12 45.2 0.2 2.3e-11 43.1 0.0 2.0 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A PRC PF05239.11 KFM01332.1 - 0.098 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 PRC-barrel domain LON PF02190.11 KFM01333.1 - 2e-21 76.6 0.0 2.6e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain Yippee-Mis18 PF03226.9 KFM01333.1 - 0.16 12.0 6.0 0.18 11.8 2.8 2.1 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly LRR_8 PF13855.1 KFM01334.1 - 9.6e-50 166.1 66.4 2.2e-12 46.5 4.1 6.7 1 1 7 8 8 8 8 Leucine rich repeat LRR_4 PF12799.2 KFM01334.1 - 4e-31 106.0 45.1 3.9e-09 35.9 1.0 7.9 4 2 3 8 8 8 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFM01334.1 - 2.7e-24 85.3 1.0 2.5e-11 43.4 2.4 4.0 2 1 2 4 4 4 3 Leucine rich repeats (6 copies) I-set PF07679.11 KFM01334.1 - 4.9e-16 58.3 0.1 3.1e-15 55.7 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin I-set domain LRR_1 PF00560.28 KFM01334.1 - 4.8e-12 44.1 38.0 0.011 15.6 0.1 12.4 13 0 0 13 13 13 3 Leucine Rich Repeat LRR_7 PF13504.1 KFM01334.1 - 2.4e-11 41.8 19.9 1.7 9.2 0.0 11.2 12 0 0 12 12 11 4 Leucine rich repeat LRR_6 PF13516.1 KFM01334.1 - 8.3e-09 34.6 36.1 0.071 13.2 0.3 11.1 10 1 1 11 11 11 4 Leucine Rich repeat V-set PF07686.12 KFM01334.1 - 2.3e-08 33.8 0.0 7.2e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.1 KFM01334.1 - 4e-08 33.6 0.6 1.5e-07 31.7 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain LRR_9 PF14580.1 KFM01334.1 - 1.6e-07 31.0 18.8 0.016 14.7 1.5 4.3 1 1 3 4 4 4 3 Leucine-rich repeat Ig_2 PF13895.1 KFM01334.1 - 7.9e-07 29.1 0.0 2.5e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFM01334.1 - 0.00011 22.1 0.9 0.0017 18.4 0.1 3.3 3 1 0 3 3 3 1 Immunoglobulin domain LRRNT PF01462.13 KFM01334.1 - 0.00014 21.2 1.0 0.00014 21.2 0.7 2.1 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain fn3 PF00041.16 KFM01334.1 - 0.001 19.1 1.5 0.0023 18.0 1.1 1.6 1 0 0 1 1 1 1 Fibronectin type III domain LRRCT PF01463.19 KFM01334.1 - 0.0029 17.7 0.1 0.0088 16.2 0.1 1.9 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain SET PF00856.23 KFM01335.1 - 7.1e-26 91.4 0.0 2.3e-25 89.8 0.0 1.8 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.11 KFM01335.1 - 2.1e-07 31.1 14.1 2.1e-07 31.1 9.8 1.9 2 0 0 2 2 2 1 Pre-SET motif FGE-sulfatase PF03781.11 KFM01336.1 - 2e-86 289.5 7.9 2.3e-86 289.3 5.4 1.0 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Hairy_orange PF07527.8 KFM01337.1 - 2.2e-08 33.7 0.3 5.3e-08 32.4 0.2 1.7 1 0 0 1 1 1 1 Hairy Orange Arf PF00025.16 KFM01338.1 - 1.1e-17 63.8 0.0 1.1e-17 63.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KFM01338.1 - 0.00029 20.2 0.0 0.00029 20.2 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KFM01338.1 - 0.0024 16.6 0.0 0.0024 16.6 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Gtr1_RagA PF04670.7 KFM01338.1 - 0.0024 17.0 0.0 0.0027 16.8 0.0 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KFM01338.1 - 0.0057 17.1 0.0 0.0057 17.1 0.0 1.0 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM01339.1 - 1e-39 135.5 0.1 1.2e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KFM01339.1 - 4.1e-15 55.5 0.0 4.6e-15 55.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM01339.1 - 9.4e-07 29.3 0.0 3e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 KFM01339.1 - 2.9e-06 26.6 0.0 3.2e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KFM01339.1 - 1.4e-05 23.9 0.1 2e-05 23.4 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit GTP_EFTU PF00009.22 KFM01339.1 - 0.0002 20.8 0.0 0.00023 20.6 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KFM01339.1 - 0.0041 16.3 0.0 0.0046 16.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Glyco_hydro_47 PF01532.15 KFM01340.1 - 9.2e-119 397.0 0.0 1.1e-118 396.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 ANF_receptor PF01094.23 KFM01341.1 - 1.3e-17 63.6 0.0 1.5e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.17 KFM01342.1 - 4.4e-85 284.8 14.7 5.9e-85 284.3 10.2 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.23 KFM01342.1 - 1.2e-74 251.1 0.0 1.7e-74 250.6 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.9 KFM01342.1 - 6.1e-15 54.6 10.1 1.1e-14 53.8 7.0 1.5 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.1 KFM01342.1 - 2.7e-05 23.6 0.0 0.00015 21.2 0.0 1.9 1 1 0 1 1 1 1 Periplasmic binding protein DUF2318 PF10080.4 KFM01342.1 - 0.14 11.9 2.2 0.42 10.4 1.5 1.7 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) PET PF06297.9 KFM01343.1 - 4.9e-41 138.6 0.0 7.5e-41 138.0 0.0 1.3 1 0 0 1 1 1 1 PET Domain LIM PF00412.17 KFM01343.1 - 5.7e-17 61.5 19.5 2e-10 40.5 2.3 3.4 3 2 0 3 3 3 2 LIM domain Caveolin PF01146.12 KFM01344.1 - 5.7e-67 223.8 1.4 6.9e-67 223.6 0.9 1.0 1 0 0 1 1 1 1 Caveolin 7tm_1 PF00001.16 KFM01345.1 - 1.6e-42 145.4 14.1 1.8e-42 145.2 9.8 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM01345.1 - 0.0012 18.0 12.5 0.0018 17.4 8.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx MENTAL PF10457.4 KFM01345.1 - 3.7 7.1 10.9 1.9 8.1 4.5 2.4 2 1 0 2 2 2 0 Cholesterol-capturing domain SAP PF02037.22 KFM01346.1 - 9.9e-12 44.0 0.3 2e-11 43.0 0.2 1.6 1 0 0 1 1 1 1 SAP domain SPT16 PF08644.6 KFM01346.1 - 0.12 12.2 6.2 0.25 11.1 4.3 1.5 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) LAGLIDADG_2 PF03161.8 KFM01346.1 - 0.27 11.1 2.7 0.24 11.2 0.6 1.7 1 1 1 2 2 2 0 LAGLIDADG DNA endonuclease family RhoGAP PF00620.22 KFM01347.1 - 3.6e-48 163.0 0.0 1.3e-47 161.2 0.0 2.0 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 KFM01347.1 - 6.7e-20 71.0 4.9 2.8e-19 69.0 3.4 2.2 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 KFM01347.1 - 1.6e-11 43.3 0.0 6.7e-11 41.4 0.0 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KFM01347.1 - 6.3e-11 41.6 0.0 1.2e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFM01347.1 - 9.3e-11 41.0 0.0 2.3e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain FlaC_arch PF05377.6 KFM01347.1 - 0.0078 16.0 0.4 0.052 13.4 0.2 2.5 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) Flg_hook PF02120.11 KFM01347.1 - 0.026 14.1 0.8 0.079 12.6 0.5 1.8 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK UPF0020 PF01170.13 KFM01348.1 - 9.4e-46 155.6 0.0 1.4e-45 155.0 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 KFM01348.1 - 2.5e-15 56.5 0.0 4.2e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain THUMP PF02926.12 KFM01348.1 - 1e-13 51.3 0.3 4.1e-12 46.1 0.0 2.4 2 0 0 2 2 2 1 THUMP domain Methyltransf_31 PF13847.1 KFM01348.1 - 0.00019 21.0 0.0 0.00069 19.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFM01348.1 - 0.005 17.2 0.0 0.019 15.4 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 KFM01348.1 - 0.008 15.5 0.0 0.022 14.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Fer4_NifH PF00142.13 KFM01348.1 - 0.098 11.8 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Methyltransf_18 PF12847.2 KFM01348.1 - 0.099 13.2 0.0 0.26 11.8 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Daxx PF03344.10 KFM01348.1 - 0.41 9.0 14.3 0.55 8.6 9.9 1.1 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 KFM01348.1 - 0.62 8.7 17.3 0.85 8.2 12.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF2151 PF10221.4 KFM01348.1 - 6.2 4.8 12.1 23 2.9 7.1 2.2 2 1 0 2 2 2 0 Cell cycle and development regulator VHL PF01847.11 KFM01349.1 - 8.5e-43 145.5 0.1 9.5e-43 145.4 0.0 1.0 1 0 0 1 1 1 1 von Hippel-Lindau disease tumour suppressor protein STAT2_C PF12188.3 KFM01349.1 - 0.11 12.2 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 Signal transducer and activator of transcription 2 C terminal Motilin_assoc PF04643.7 KFM01350.1 - 2.7e-18 65.1 0.0 3e-17 61.8 0.0 2.1 2 0 0 2 2 2 1 Motilin/ghrelin-associated peptide Motilin_ghrelin PF04644.7 KFM01350.1 - 0.0074 16.0 0.4 0.015 15.0 0.3 1.6 1 0 0 1 1 1 1 Motilin/ghrelin YhfH PF14149.1 KFM01350.1 - 0.024 14.4 0.5 0.044 13.5 0.3 1.4 1 0 0 1 1 1 0 YhfH-like protein WTX PF09422.5 KFM01350.1 - 0.034 13.1 0.2 0.042 12.8 0.1 1.1 1 0 0 1 1 1 0 WTX protein Zn-ribbon_8 PF09723.5 KFM01350.1 - 0.043 13.7 0.1 0.064 13.2 0.1 1.3 1 0 0 1 1 1 0 Zinc ribbon domain WD40 PF00400.27 KFM01351.1 - 1.6e-48 160.8 23.3 3.6e-10 39.3 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 KFM01351.1 - 0.15 11.7 12.2 0.26 10.9 0.6 4.3 2 2 3 5 5 5 0 Transcription factor IIIC subunit delta N-term Ribosomal_L32e PF01655.13 KFM01352.1 - 1.1e-50 170.3 4.2 1.3e-50 170.0 2.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 CAAP1 PF15335.1 KFM01352.1 - 0.085 13.0 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Caspase activity and apoptosis inhibitor 1 DUF1947 PF09183.5 KFM01352.1 - 0.3 10.8 2.4 0.35 10.6 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1947) Vps4_C PF09336.5 KFM01353.1 - 0.0056 16.5 0.1 0.014 15.2 0.1 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain HhH-GPD PF00730.20 KFM01354.1 - 1.3e-06 28.6 0.0 1.6e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein WD40 PF00400.27 KFM01355.1 - 5.2e-27 92.7 14.5 9.3e-10 38.0 0.0 7.2 6 1 0 6 6 6 5 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KFM01355.1 - 6.3e-06 25.2 8.9 0.0023 16.8 0.2 4.9 5 1 0 5 5 5 2 Coatomer WD associated region Apc3 PF12895.2 KFM01355.1 - 0.002 18.2 6.9 0.62 10.2 0.2 4.4 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KFM01355.1 - 0.0067 16.1 6.8 0.034 13.9 0.1 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat zf-RING_2 PF13639.1 KFM01355.1 - 0.0072 16.1 3.8 0.035 13.9 2.7 2.3 1 0 0 1 1 1 1 Ring finger domain Clathrin PF00637.15 KFM01355.1 - 0.009 15.6 3.6 0.22 11.1 0.1 3.6 1 1 3 4 4 4 1 Region in Clathrin and VPS TPR_2 PF07719.12 KFM01355.1 - 0.1 12.5 19.5 0.17 11.8 0.5 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 KFM01355.1 - 0.25 11.3 6.3 0.78 9.7 0.1 4.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFM01355.1 - 1 10.1 5.9 50 4.9 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.1 KFM01355.1 - 2.4 7.8 11.3 27 4.5 1.9 4.9 5 1 0 5 5 5 0 TPR repeat 7tm_1 PF00001.16 KFM01356.1 - 2.4e-51 174.3 13.5 3.3e-51 173.9 9.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Rhodopsin_N PF10413.4 KFM01356.1 - 8.3e-26 89.3 1.5 2.1e-25 88.0 1.0 1.8 1 0 0 1 1 1 1 Amino terminal of the G-protein receptor rhodopsin 7TM_GPCR_Srsx PF10320.4 KFM01356.1 - 1.6e-09 37.3 16.9 2.1e-09 36.9 11.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 KFM01356.1 - 1.8e-09 37.1 17.7 2.9e-09 36.4 12.3 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.4 KFM01356.1 - 6.8e-09 35.2 19.2 4.8e-08 32.4 13.3 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw TAS2R PF05296.8 KFM01356.1 - 0.00054 18.9 8.5 0.0019 17.1 0.8 2.1 2 0 0 2 2 2 2 Mammalian taste receptor protein (TAS2R) 7TM_GPCR_Srx PF10328.4 KFM01356.1 - 0.0019 17.3 21.4 0.0042 16.2 14.9 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 60KD_IMP PF02096.15 KFM01356.1 - 1.5 8.4 12.4 1 9.0 6.5 2.2 1 1 1 2 2 2 0 60Kd inner membrane protein Tmemb_cc2 PF10267.4 KFM01358.1 - 6.1e-180 597.9 14.1 6.1e-180 597.9 9.8 1.6 2 0 0 2 2 2 1 Predicted transmembrane and coiled-coil 2 protein TRH PF05438.7 KFM01359.1 - 2.5e-60 203.4 9.7 5.6e-57 192.5 4.5 2.0 2 0 0 2 2 2 2 Thyrotropin-releasing hormone (TRH) Med2 PF11214.3 KFM01359.1 - 0.00063 19.7 0.1 0.0014 18.6 0.0 1.7 2 0 0 2 2 2 1 Mediator complex subunit 2 Ribosomal_L35p PF01632.14 KFM01359.1 - 6.4 6.7 7.2 15 5.5 0.1 3.8 3 1 1 4 4 4 0 Ribosomal protein L35 Rbsn PF11464.3 KFM01360.1 - 1.5e-43 146.0 14.7 9.9e-22 76.2 0.4 2.7 2 0 0 2 2 2 2 Rabenosyn Rab binding domain FYVE PF01363.16 KFM01360.1 - 7e-19 67.4 6.4 2.7e-18 65.6 4.4 2.1 1 0 0 1 1 1 1 FYVE zinc finger HypA PF01155.14 KFM01360.1 - 0.0029 17.2 0.4 0.0029 17.2 0.3 2.9 3 0 0 3 3 3 1 Hydrogenase expression/synthesis hypA family TerY-C PF15616.1 KFM01360.1 - 0.018 14.9 2.2 0.09 12.7 0.1 2.8 2 0 0 2 2 2 0 TerY-C metal binding domain zf-Di19 PF05605.7 KFM01360.1 - 0.022 14.8 0.1 0.022 14.8 0.1 2.9 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding UPF0489 PF12640.2 KFM01360.1 - 0.03 14.4 1.0 0.13 12.4 0.7 2.0 1 0 0 1 1 1 0 UPF0489 domain RNA_POL_M_15KD PF02150.11 KFM01360.1 - 0.045 13.4 6.0 0.035 13.8 0.8 2.7 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zf-AD PF07776.10 KFM01360.1 - 1.3 9.0 0.0 1.3 9.0 0.0 4.1 3 1 1 4 4 4 0 Zinc-finger associated domain (zf-AD) zf-RING_3 PF14369.1 KFM01360.1 - 1.7 8.7 7.4 0.36 10.8 0.1 3.0 3 0 0 3 3 3 0 zinc-finger L51_S25_CI-B8 PF05047.11 KFM01361.1 - 1.6e-13 50.1 0.4 2.6e-13 49.4 0.3 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Hormone_recep PF00104.25 KFM01362.1 - 3.8e-36 124.1 2.2 6.2e-36 123.4 1.5 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFM01362.1 - 4.1e-32 110.2 16.3 8e-32 109.2 11.3 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) XS PF03468.9 KFM01362.1 - 0.12 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 XS domain WD40 PF00400.27 KFM01363.1 - 2.3e-20 71.6 9.2 3.1e-05 23.6 0.0 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat PQQ_3 PF13570.1 KFM01363.1 - 0.011 15.9 0.0 53 4.2 0.0 4.3 4 0 0 4 4 4 0 PQQ-like domain MMS1_N PF10433.4 KFM01363.1 - 0.032 12.3 0.0 0.17 9.9 0.0 2.0 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Xan_ur_permease PF00860.15 KFM01364.1 - 4.9e-89 298.5 24.7 6.4e-89 298.1 17.1 1.1 1 0 0 1 1 1 1 Permease family zf-RING_4 PF14570.1 KFM01365.1 - 6.4e-20 70.4 12.0 1.2e-19 69.6 8.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_5 PF13893.1 KFM01365.1 - 4.1e-06 26.5 0.0 8.1e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFM01365.1 - 8.5e-06 25.3 0.0 1.9e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 KFM01365.1 - 1.3e-05 24.7 6.9 2.5e-05 23.8 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_6 PF14259.1 KFM01365.1 - 5.1e-05 23.1 0.0 0.0001 22.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4 PF00097.20 KFM01365.1 - 0.029 14.0 9.9 0.062 12.9 6.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 KFM01365.1 - 0.033 13.9 5.1 0.074 12.8 3.5 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_2 PF13923.1 KFM01365.1 - 0.036 14.1 11.3 0.08 12.9 7.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM01365.1 - 0.24 11.1 8.8 0.48 10.1 6.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DUF3414 PF11894.3 KFM01366.1 - 0 1723.7 11.2 0 1723.5 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) Arf PF00025.16 KFM01367.1 - 1.1e-75 252.7 0.1 1.2e-75 252.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KFM01367.1 - 1.7e-13 50.2 0.0 2e-13 50.0 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KFM01367.1 - 1.4e-11 43.9 0.0 1.7e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KFM01367.1 - 2.8e-11 42.7 1.2 1.1e-07 30.9 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KFM01367.1 - 3.6e-11 42.6 0.0 4.4e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KFM01367.1 - 5.1e-09 36.6 0.0 6.7e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KFM01367.1 - 7.8e-06 25.8 0.0 1.2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFM01367.1 - 0.0002 20.8 0.3 0.0024 17.3 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 KFM01367.1 - 0.00078 18.2 0.6 0.047 12.4 0.0 2.6 2 1 1 3 3 3 1 ArgK protein ABC_tran PF00005.22 KFM01367.1 - 0.014 15.6 0.3 0.08 13.2 0.2 1.9 1 1 0 1 1 1 0 ABC transporter FeoB_N PF02421.13 KFM01367.1 - 0.023 13.9 0.9 0.17 11.1 0.6 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.4 KFM01367.1 - 0.046 13.2 0.3 1.7 8.1 0.1 2.6 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 KFM01367.1 - 0.053 12.9 0.2 4.2 6.7 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KFM01367.1 - 0.14 12.0 0.1 0.73 9.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain DRIM PF07539.7 KFM01368.1 - 7.4e-49 164.7 0.4 3.9e-48 162.4 0.3 2.4 1 0 0 1 1 1 1 Down-regulated in metastasis Arm PF00514.18 KFM01368.1 - 3.4 7.6 6.0 27 4.7 0.0 4.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Anoctamin PF04547.7 KFM01369.1 - 2e-159 531.0 12.1 2.5e-159 530.7 8.4 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel GAS2 PF02187.12 KFM01370.1 - 5.8e-29 99.6 0.0 1.1e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.26 KFM01370.1 - 7.5e-07 29.1 0.1 1.2e-06 28.4 0.1 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Hormone_recep PF00104.25 KFM01371.1 - 1.4e-33 115.7 1.4 2.4e-33 114.9 1.0 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFM01371.1 - 7.4e-29 99.7 14.7 7.4e-29 99.7 10.2 1.7 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) MFS_1 PF07690.11 KFM01372.1 - 1.1e-48 165.7 40.4 6.3e-47 159.9 19.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 KFM01373.1 - 1.4e-25 89.9 0.0 2.8e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM01373.1 - 5.9e-16 58.3 0.0 3.1e-15 55.9 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Strep_67kDa_ant PF06100.6 KFM01373.1 - 0.012 14.0 1.7 0.017 13.4 1.1 1.1 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family SDF PF00375.13 KFM01374.1 - 3.5e-136 454.0 29.4 4e-136 453.8 20.4 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family MT PF12777.2 KFM01374.1 - 0.035 12.8 0.0 0.056 12.1 0.0 1.2 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor Lon_C PF05362.8 KFM01375.1 - 5.2e-26 91.2 0.0 1.9e-25 89.3 0.0 2.0 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 KFM01375.1 - 7e-25 87.7 0.0 3.2e-24 85.6 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 KFM01375.1 - 1.1e-23 84.0 8.4 1.1e-23 84.0 5.8 2.6 2 1 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA_5 PF07728.9 KFM01375.1 - 4.9e-09 36.0 0.0 1.7e-08 34.2 0.0 2.0 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KFM01375.1 - 2.1e-08 34.2 0.0 7.6e-08 32.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KFM01375.1 - 2.6e-07 29.9 0.0 1.3e-05 24.4 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_PrkA PF08298.6 KFM01375.1 - 2.3e-06 26.5 0.0 4.5e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.1 KFM01375.1 - 2.3e-06 27.7 3.5 0.0001 22.4 0.0 4.1 4 1 0 4 4 4 1 AAA domain AAA_16 PF13191.1 KFM01375.1 - 3.7e-06 27.0 1.8 1.6e-05 25.0 0.0 3.0 3 1 0 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 KFM01375.1 - 9.6e-06 26.4 2.5 5.5e-05 23.9 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 KFM01375.1 - 2.2e-05 24.3 0.5 8.5e-05 22.4 0.0 2.4 3 0 0 3 3 1 1 AAA domain RNA_helicase PF00910.17 KFM01375.1 - 0.0012 19.0 0.0 0.0032 17.6 0.0 1.9 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.12 KFM01375.1 - 0.0032 16.8 0.0 0.007 15.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.1 KFM01375.1 - 0.0042 16.6 0.0 0.0092 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Acetate_kinase PF00871.12 KFM01375.1 - 0.0043 15.6 1.0 0.0066 15.0 0.7 1.3 1 0 0 1 1 1 1 Acetokinase family AAA_25 PF13481.1 KFM01375.1 - 0.007 15.7 0.0 0.031 13.6 0.0 2.1 2 0 0 2 2 1 1 AAA domain NTPase_1 PF03266.10 KFM01375.1 - 0.0097 15.6 0.3 0.24 11.0 0.0 2.9 2 1 1 3 3 2 1 NTPase AAA_18 PF13238.1 KFM01375.1 - 0.016 15.5 0.0 0.016 15.5 0.0 3.4 3 1 0 3 3 3 0 AAA domain AAA_3 PF07726.6 KFM01375.1 - 0.017 14.7 0.0 0.16 11.5 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KFM01375.1 - 0.024 14.3 0.0 0.12 11.9 0.0 2.3 1 1 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.18 KFM01375.1 - 0.043 13.7 0.2 1.1 9.2 0.0 3.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase ABC_tran PF00005.22 KFM01375.1 - 0.045 14.0 1.0 0.47 10.7 0.0 2.9 2 1 0 2 2 2 0 ABC transporter DUF258 PF03193.11 KFM01375.1 - 0.045 12.9 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Parvo_NS1 PF01057.12 KFM01375.1 - 0.054 12.3 0.0 0.15 10.8 0.0 1.8 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATP-synt_ab PF00006.20 KFM01375.1 - 0.056 12.9 0.0 0.084 12.3 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain UPF0079 PF02367.12 KFM01375.1 - 0.06 12.9 0.0 0.18 11.4 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 KFM01375.1 - 0.064 13.1 0.0 0.22 11.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 KFM01375.1 - 0.07 13.0 1.0 1.8 8.4 0.0 2.8 2 1 1 3 3 3 0 AAA domain AAA_19 PF13245.1 KFM01375.1 - 0.11 12.2 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_23 PF13476.1 KFM01375.1 - 0.18 12.0 0.0 0.18 12.0 0.0 3.4 2 1 0 2 2 1 0 AAA domain AAA_11 PF13086.1 KFM01375.1 - 2.8 7.4 0.0 2.8 7.4 0.0 3.2 1 1 0 2 2 1 0 AAA domain Lon_C PF05362.8 KFM01376.1 - 2.2e-40 138.1 0.0 2.5e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain ChlI PF13541.1 KFM01376.1 - 8.3e-09 35.0 0.0 1.1e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase Ribosomal_L36e PF01158.13 KFM01377.1 - 2.3e-35 120.4 5.2 2.6e-35 120.3 3.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Filament PF00038.16 KFM01378.1 - 7.2e-100 334.4 57.1 9.4e-100 334.0 39.6 1.1 1 0 0 1 1 1 1 Intermediate filament protein LTD PF00932.14 KFM01378.1 - 6.3e-20 71.4 0.5 1.2e-19 70.4 0.4 1.4 1 0 0 1 1 1 1 Lamin Tail Domain Myosin_tail_1 PF01576.14 KFM01378.1 - 1.1e-05 23.4 67.2 0.00041 18.2 6.5 3.3 1 1 2 3 3 3 3 Myosin tail BRE1 PF08647.6 KFM01378.1 - 0.00051 19.9 6.7 0.00051 19.9 4.6 4.1 3 0 0 3 3 3 1 BRE1 E3 ubiquitin ligase DUF869 PF05911.6 KFM01378.1 - 0.0042 15.4 8.6 0.0042 15.4 6.0 2.7 1 1 2 3 3 3 1 Plant protein of unknown function (DUF869) CagE_TrbE_VirB PF03135.9 KFM01378.1 - 0.0083 15.9 0.7 0.022 14.5 0.5 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system ADIP PF11559.3 KFM01378.1 - 0.013 15.4 1.9 0.013 15.4 1.3 4.5 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 KFM01378.1 - 0.09 13.1 0.4 0.09 13.1 0.3 6.1 1 1 5 6 6 6 0 Protein of unknown function (DUF972) Atg14 PF10186.4 KFM01378.1 - 9.4 5.0 43.1 0.67 8.8 11.2 3.0 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 zf-Tim10_DDP PF02953.10 KFM01379.1 - 2e-19 68.6 0.6 2.3e-19 68.4 0.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger FANCI_S3 PF14677.1 KFM01379.1 - 0.11 11.8 0.0 0.13 11.5 0.0 1.0 1 0 0 1 1 1 0 FANCI solenoid 3 Trypsin PF00089.21 KFM01380.1 - 1.4e-69 234.0 0.0 1.5e-69 233.9 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 KFM01380.1 - 0.00019 20.7 0.0 0.00026 20.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 KFM01380.1 - 0.008 16.1 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_A22B PF04258.8 KFM01381.1 - 3.2e-89 299.3 16.1 4.5e-89 298.8 11.1 1.2 1 0 0 1 1 1 1 Signal peptide peptidase PA PF02225.17 KFM01381.1 - 4e-13 48.9 0.0 7.9e-13 47.9 0.0 1.4 1 0 0 1 1 1 1 PA domain DUF4064 PF13273.1 KFM01381.1 - 0.096 12.7 2.4 0.46 10.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF4191 PF13829.1 KFM01381.1 - 4.4 6.3 9.1 0.61 9.1 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) LSM PF01423.17 KFM01382.1 - 1.6e-18 66.0 0.0 1.9e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain Kelch_1 PF01344.20 KFM01383.1 - 5.5e-25 86.6 14.4 3.9e-05 23.1 0.6 6.9 6 1 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 KFM01383.1 - 7.2e-23 79.7 10.9 4.5e-05 23.4 0.1 6.4 4 2 2 6 6 6 5 Kelch motif BACK PF07707.10 KFM01383.1 - 2.2e-21 75.6 1.5 5.6e-21 74.3 0.3 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_5 PF13854.1 KFM01383.1 - 6.5e-08 32.3 5.1 0.12 12.3 0.1 5.6 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 KFM01383.1 - 4.7e-07 29.3 9.4 0.23 11.2 0.1 5.9 5 1 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 KFM01383.1 - 5.8e-07 29.4 9.0 0.005 16.9 0.1 5.3 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_4 PF13418.1 KFM01383.1 - 3.9e-06 26.5 20.0 0.1 12.3 0.1 7.0 5 2 1 6 6 6 4 Galactose oxidase, central domain BTB PF00651.26 KFM01383.1 - 4.4e-06 26.6 0.1 7e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain Pepsin-I3 PF06394.8 KFM01383.1 - 3 7.5 4.7 6.6 6.4 0.1 3.1 4 0 0 4 4 4 0 Pepsin inhibitor-3-like repeated domain TRAM_LAG1_CLN8 PF03798.11 KFM01384.1 - 9e-35 120.0 28.5 1.2e-34 119.6 19.8 1.1 1 0 0 1 1 1 1 TLC domain Homeobox PF00046.24 KFM01384.1 - 0.00012 21.6 0.0 0.00025 20.5 0.0 1.5 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 KFM01384.1 - 0.0032 16.4 0.1 0.011 14.8 0.0 1.9 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez CLAMP PF14769.1 KFM01385.1 - 1.9e-06 27.9 0.0 2.4e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 UCH PF00443.24 KFM01386.1 - 7.3e-30 103.9 0.0 1.3e-29 103.1 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFM01386.1 - 4.4e-13 49.3 0.0 5.5e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 KFM01386.1 - 0.023 13.9 2.1 0.12 11.6 0.1 2.5 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase SET PF00856.23 KFM01387.1 - 8.1e-25 88.0 0.1 8.1e-25 88.0 0.0 4.6 4 1 0 4 4 4 1 SET domain WW PF00397.21 KFM01387.1 - 1.6e-09 37.4 3.7 1.6e-09 37.4 2.5 2.1 2 0 0 2 2 2 1 WW domain Kinesin PF00225.18 KFM01388.1 - 1.9e-95 319.3 0.2 2.8e-95 318.8 0.1 1.3 1 0 0 1 1 1 1 Kinesin motor domain AAA_22 PF13401.1 KFM01388.1 - 0.0055 16.8 0.9 0.095 12.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain ResIII PF04851.10 KFM01388.1 - 1.7 8.4 7.7 1.2 8.9 0.1 2.9 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit FAST_1 PF06743.10 KFM01389.1 - 1e-05 25.1 0.1 1.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 FAST kinase-like protein, subdomain 1 PID PF00640.18 KFM01390.1 - 0.002 18.1 0.0 0.012 15.6 0.0 2.1 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) WD40 PF00400.27 KFM01391.1 - 2.5e-08 33.4 0.5 0.0025 17.6 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF2348 PF09807.4 KFM01392.1 - 2.8e-101 337.8 1.9 3.1e-101 337.6 1.3 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2348) DUF2328 PF10090.4 KFM01392.1 - 0.056 12.6 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2328) KaiC PF06745.8 KFM01392.1 - 0.13 11.3 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 KaiC SWIRM PF04433.12 KFM01393.1 - 7.3e-34 115.7 2.8 1e-33 115.2 0.0 2.4 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.26 KFM01393.1 - 3e-09 36.7 0.2 6.4e-09 35.7 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFM01393.1 - 6.2e-08 32.6 0.0 1.9e-07 31.0 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF2618 PF10940.3 KFM01393.1 - 0.016 14.9 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2618) HA2 PF04408.18 KFM01394.1 - 1.2e-16 60.5 0.1 8.4e-16 57.8 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KFM01394.1 - 1.8e-12 46.9 0.1 4.2e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.20 KFM01394.1 - 2.2e-10 40.9 2.0 9.2e-05 22.9 0.4 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif DEAD PF00270.24 KFM01394.1 - 5.3e-07 29.2 0.0 9.8e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 KFM01394.1 - 1.2e-06 28.2 0.0 3.1e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 KFM01394.1 - 0.00074 19.6 0.0 0.0032 17.5 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFM01394.1 - 0.0053 16.4 0.1 0.016 14.9 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain HEAT_2 PF13646.1 KFM01394.1 - 0.023 14.9 0.7 0.12 12.6 0.2 2.4 2 0 0 2 2 2 0 HEAT repeats PhoH PF02562.11 KFM01394.1 - 0.076 12.2 0.0 0.82 8.8 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein Miro PF08477.8 KFM01394.1 - 0.11 12.9 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein ABC_tran PF00005.22 KFM01394.1 - 0.13 12.5 0.0 0.5 10.6 0.0 2.0 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 KFM01394.1 - 0.23 11.7 0.0 0.45 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Tubulin-binding PF00418.14 KFM01395.1 - 2.6e-46 154.9 23.3 1.4e-17 63.0 3.9 3.1 3 0 0 3 3 3 3 Tau and MAP protein, tubulin-binding repeat M-inducer_phosp PF06617.8 KFM01398.1 - 1.5e-52 178.2 7.8 2.2e-52 177.6 5.4 1.2 1 0 0 1 1 1 1 M-phase inducer phosphatase Rhodanese PF00581.15 KFM01398.1 - 8.7e-16 58.2 0.0 1.9e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain PRY PF13765.1 KFM01399.1 - 8.7e-21 73.1 0.0 1.8e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 SPRY-associated domain DUF2935 PF11155.3 KFM01399.1 - 0.033 14.2 0.4 0.096 12.7 0.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) DUF445 PF04286.7 KFM01399.1 - 0.058 12.9 0.3 0.068 12.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) PhoU PF01895.14 KFM01399.1 - 0.19 12.1 1.5 1.8 9.0 0.1 2.1 2 0 0 2 2 2 0 PhoU domain zf-C2H2 PF00096.21 KFM01401.1 - 1.4e-12 47.1 6.5 7.3e-07 29.1 0.6 2.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM01401.1 - 1.4e-09 37.7 0.4 1.4e-09 37.7 0.3 2.6 3 0 0 3 3 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM01401.1 - 1.2e-07 31.5 6.2 0.00018 21.6 0.7 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 KFM01401.1 - 0.0002 21.2 1.2 0.0058 16.5 0.8 2.1 1 1 0 1 1 1 1 Zinc ribbon domain zf-C2H2_jaz PF12171.3 KFM01401.1 - 0.00029 20.8 2.3 0.2 11.8 0.1 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFM01401.1 - 0.00049 19.8 4.1 0.097 12.6 0.2 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger YhfH PF14149.1 KFM01401.1 - 0.0055 16.4 0.3 0.62 9.9 0.0 2.2 2 0 0 2 2 2 1 YhfH-like protein zf-IS66 PF13005.2 KFM01401.1 - 0.0075 16.2 0.3 2 8.4 0.0 2.1 2 0 0 2 2 2 1 zinc-finger binding domain of transposase IS66 DUF2688 PF10892.3 KFM01401.1 - 0.015 14.9 0.6 0.78 9.4 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) DNA_RNApol_7kD PF03604.8 KFM01401.1 - 0.016 14.6 1.0 1.2 8.6 0.1 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-ribbon_3 PF13248.1 KFM01401.1 - 0.016 14.3 0.9 2.2 7.6 0.0 2.1 2 0 0 2 2 2 0 zinc-ribbon domain C1_1 PF00130.17 KFM01401.1 - 0.017 14.8 0.1 0.042 13.5 0.0 1.6 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_Tnp_IS1595 PF12760.2 KFM01401.1 - 0.021 14.6 2.5 0.038 13.7 1.7 1.5 1 1 0 1 1 1 0 Transposase zinc-ribbon domain XPA_N PF01286.13 KFM01401.1 - 0.022 14.4 2.7 0.83 9.3 0.1 2.1 2 0 0 2 2 2 0 XPA protein N-terminal DZR PF12773.2 KFM01401.1 - 0.024 14.4 0.4 0.033 14.0 0.3 1.2 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 KFM01401.1 - 0.04 13.4 5.1 1.5 8.4 0.3 2.1 2 0 0 2 2 2 0 zinc-ribbon domain HNH PF01844.18 KFM01401.1 - 0.041 13.7 2.5 2.3 8.1 0.1 2.3 2 0 0 2 2 2 0 HNH endonuclease Prok-RING_1 PF14446.1 KFM01401.1 - 0.052 13.2 0.5 2.1 8.1 0.0 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Ogr_Delta PF04606.7 KFM01401.1 - 0.057 13.0 0.6 0.15 11.7 0.4 1.8 1 1 0 1 1 1 0 Ogr/Delta-like zinc finger TFIIS_C PF01096.13 KFM01401.1 - 0.065 12.8 3.1 0.5 10.0 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-FCS PF06467.9 KFM01401.1 - 0.065 12.8 0.6 0.59 9.8 0.6 2.0 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Ribosomal_L44 PF00935.14 KFM01401.1 - 0.069 13.1 1.4 0.58 10.2 0.3 2.0 1 1 1 2 2 2 0 Ribosomal protein L44 zinc_ribbon_4 PF13717.1 KFM01401.1 - 0.079 12.6 2.5 0.5 10.1 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 KFM01401.1 - 0.092 12.0 1.1 0.85 8.9 0.0 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding zf-ISL3 PF14690.1 KFM01401.1 - 0.097 12.7 4.4 0.98 9.5 0.4 2.4 2 1 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C2H2_2 PF12756.2 KFM01401.1 - 0.11 12.6 0.5 7.1 6.7 0.0 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Arc_trans_TRASH PF08394.5 KFM01401.1 - 0.11 12.7 0.3 0.94 9.6 0.3 2.1 1 1 1 2 2 2 0 Archaeal TRASH domain zinc_ribbon_5 PF13719.1 KFM01401.1 - 0.11 12.1 2.5 0.61 9.7 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2HC_2 PF13913.1 KFM01401.1 - 0.13 11.9 3.1 5 6.8 0.2 2.4 2 1 0 2 2 2 0 zinc-finger of a C2HC-type C1_4 PF07975.7 KFM01401.1 - 0.14 12.2 0.9 0.2 11.7 0.6 1.3 1 0 0 1 1 1 0 TFIIH C1-like domain A2L_zn_ribbon PF08792.5 KFM01401.1 - 0.14 11.6 5.2 0.76 9.3 0.2 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain Zn_ribbon_recom PF13408.1 KFM01401.1 - 0.15 12.3 1.2 0.33 11.2 0.8 1.6 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-UBP PF02148.14 KFM01401.1 - 0.18 11.9 1.2 0.28 11.3 0.8 1.4 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-met PF12874.2 KFM01401.1 - 0.21 11.8 0.2 0.21 11.8 0.1 1.7 2 1 0 2 2 2 0 Zinc-finger of C2H2 type DUF2072 PF09845.4 KFM01401.1 - 0.22 11.4 1.4 8 6.3 0.1 2.0 2 0 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) DUF2256 PF10013.4 KFM01401.1 - 0.25 11.1 2.1 3.4 7.4 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-BED PF02892.10 KFM01401.1 - 0.26 11.0 3.8 2.4 7.9 0.1 2.3 1 1 1 2 2 2 0 BED zinc finger UPF0547 PF10571.4 KFM01401.1 - 0.41 10.3 1.8 7.7 6.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-RING_3 PF14369.1 KFM01401.1 - 0.42 10.6 2.9 1.3 9.0 0.0 2.1 2 0 0 2 2 2 0 zinc-finger zf-trcl PF13451.1 KFM01401.1 - 0.6 9.7 2.7 1.4 8.6 0.1 2.1 2 0 0 2 2 2 0 Probable zinc-binding domain zf-AN1 PF01428.11 KFM01401.1 - 0.84 9.5 4.7 1.2 9.0 0.1 2.2 2 0 0 2 2 2 0 AN1-like Zinc finger DUF1610 PF07754.6 KFM01401.1 - 5.9 7.0 6.1 11 6.2 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) zf-CHCC PF10276.4 KFM01401.1 - 9.6 6.1 6.4 12 5.8 1.5 2.1 2 0 0 2 2 2 0 Zinc-finger domain zf-C2H2 PF00096.21 KFM01402.1 - 8.7e-11 41.5 8.7 3.2e-06 27.1 1.2 2.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM01402.1 - 4.3e-10 39.3 1.2 4.3e-10 39.3 0.8 2.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 KFM01402.1 - 9.6e-09 34.8 3.7 8.2e-05 22.3 0.7 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KFM01402.1 - 4.2e-07 29.8 6.0 0.00094 19.3 0.7 2.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM01402.1 - 0.0054 16.8 7.1 0.41 10.8 0.2 2.4 2 1 0 2 2 2 2 Zinc-finger double-stranded RNA-binding XPA_N PF01286.13 KFM01402.1 - 0.0068 16.0 7.0 0.029 14.0 0.6 2.1 2 0 0 2 2 2 1 XPA protein N-terminal Zn-ribbon_8 PF09723.5 KFM01402.1 - 0.0083 16.0 1.6 0.82 9.6 0.1 2.1 2 0 0 2 2 2 1 Zinc ribbon domain C1_1 PF00130.17 KFM01402.1 - 0.013 15.2 0.0 0.027 14.1 0.0 1.5 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-met PF12874.2 KFM01402.1 - 0.014 15.5 2.0 2.1 8.6 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type C1_3 PF07649.7 KFM01402.1 - 0.022 14.7 0.6 0.084 12.9 0.0 1.9 2 1 0 2 2 2 0 C1-like domain Zn_ribbon_recom PF13408.1 KFM01402.1 - 0.036 14.3 1.9 0.044 14.0 1.3 1.2 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-LYAR PF08790.6 KFM01402.1 - 0.037 13.7 1.3 1.8 8.2 0.1 2.2 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-H2C2_5 PF13909.1 KFM01402.1 - 0.058 13.6 3.3 0.56 10.5 0.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc-finger domain C1_4 PF07975.7 KFM01402.1 - 0.059 13.3 0.8 0.14 12.1 0.6 1.6 1 1 0 1 1 1 0 TFIIH C1-like domain Prok-RING_1 PF14446.1 KFM01402.1 - 0.077 12.7 0.9 4.1 7.2 0.1 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 TFIIS_C PF01096.13 KFM01402.1 - 0.084 12.5 3.0 1.2 8.8 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) DNA_RNApol_7kD PF03604.8 KFM01402.1 - 0.11 12.0 1.6 2.1 7.8 0.1 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-C2H2_7 PF15269.1 KFM01402.1 - 0.12 12.2 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Zinc-finger DZR PF12773.2 KFM01402.1 - 0.12 12.1 0.8 0.16 11.8 0.5 1.2 1 0 0 1 1 1 0 Double zinc ribbon SprT-like PF10263.4 KFM01402.1 - 0.14 11.8 1.0 0.16 11.6 0.7 1.2 1 0 0 1 1 1 0 SprT-like family YhfH PF14149.1 KFM01402.1 - 0.14 11.9 1.8 8.3 6.2 0.1 2.1 2 0 0 2 2 2 0 YhfH-like protein zinc_ribbon_5 PF13719.1 KFM01402.1 - 0.14 11.7 0.8 2.7 7.6 0.6 2.1 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KFM01402.1 - 0.22 11.2 1.1 4.7 6.9 0.8 2.1 1 1 0 1 1 1 0 zinc-ribbon domain Ribosomal_L44 PF00935.14 KFM01402.1 - 0.25 11.3 2.2 5.9 6.9 0.8 2.1 1 1 1 2 2 2 0 Ribosomal protein L44 Zn_Tnp_IS1595 PF12760.2 KFM01402.1 - 0.27 11.0 4.0 0.47 10.3 2.8 1.4 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-AN1 PF01428.11 KFM01402.1 - 0.49 10.3 4.5 2.4 8.1 0.9 2.2 1 1 1 2 2 2 0 AN1-like Zinc finger zf-trcl PF13451.1 KFM01402.1 - 1.6 8.4 4.2 15 5.2 0.1 2.2 2 0 0 2 2 2 0 Probable zinc-binding domain A2L_zn_ribbon PF08792.5 KFM01402.1 - 1.7 8.2 4.3 16 5.0 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-C2H2 PF00096.21 KFM01403.1 - 9e-25 85.4 34.4 1.6e-07 31.2 1.5 4.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM01403.1 - 2e-21 75.1 31.5 4.3e-10 39.3 0.3 4.8 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM01403.1 - 4.5e-17 61.0 31.0 8.6e-05 22.5 1.1 4.1 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM01403.1 - 5.9e-07 29.1 22.4 0.0091 15.8 0.8 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger C1_1 PF00130.17 KFM01403.1 - 7.3e-06 25.6 3.4 0.037 13.7 1.1 2.7 1 1 1 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_jaz PF12171.3 KFM01403.1 - 6.7e-05 22.9 19.5 0.022 14.8 0.1 4.3 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 KFM01403.1 - 0.0018 18.2 16.1 1.5 8.8 0.2 4.1 3 1 0 3 3 3 2 Zinc ribbon domain XPA_N PF01286.13 KFM01403.1 - 0.0057 16.2 13.0 0.32 10.7 0.3 4.2 4 0 0 4 4 4 1 XPA protein N-terminal Zn_Tnp_IS1595 PF12760.2 KFM01403.1 - 0.0062 16.3 16.9 0.34 10.7 1.9 2.9 2 2 0 2 2 2 2 Transposase zinc-ribbon domain zf-BED PF02892.10 KFM01403.1 - 0.01 15.5 0.4 0.01 15.5 0.3 4.2 1 1 2 3 3 2 0 BED zinc finger Zn_ribbon_recom PF13408.1 KFM01403.1 - 0.011 15.9 16.1 0.51 10.6 1.4 2.7 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-C4_ClpX PF06689.8 KFM01403.1 - 0.012 15.0 8.2 0.31 10.5 0.3 3.8 3 1 0 3 3 3 0 ClpX C4-type zinc finger TFIIS_C PF01096.13 KFM01403.1 - 0.023 14.3 11.5 4.7 6.9 0.0 4.1 4 0 0 4 4 4 0 Transcription factor S-II (TFIIS) zf-met PF12874.2 KFM01403.1 - 0.025 14.7 24.2 0.64 10.3 0.8 4.3 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_7 PF15269.1 KFM01403.1 - 0.026 14.3 0.8 0.026 14.3 0.6 3.1 1 1 2 3 3 3 0 Zinc-finger TF_Zn_Ribbon PF08271.7 KFM01403.1 - 0.03 13.6 7.6 0.061 12.6 0.1 3.1 3 0 0 3 3 3 0 TFIIB zinc-binding zf-CHY PF05495.7 KFM01403.1 - 0.05 13.7 15.4 0.1 12.7 3.8 2.5 1 1 1 2 2 2 0 CHY zinc finger zf-C2HC_2 PF13913.1 KFM01403.1 - 0.053 13.1 0.6 0.053 13.1 0.4 3.9 5 0 0 5 5 3 0 zinc-finger of a C2HC-type rve PF00665.21 KFM01403.1 - 0.057 13.5 0.2 0.072 13.1 0.1 1.2 1 0 0 1 1 1 0 Integrase core domain C1_3 PF07649.7 KFM01403.1 - 0.067 13.2 12.7 0.31 11.1 0.1 3.9 4 0 0 4 4 4 0 C1-like domain DUF2197 PF09963.4 KFM01403.1 - 0.13 12.2 8.7 1.6 8.7 0.6 3.2 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2197) C1_4 PF07975.7 KFM01403.1 - 0.16 12.0 12.2 0.64 10.0 0.5 3.2 1 1 2 3 3 3 0 TFIIH C1-like domain DZR PF12773.2 KFM01403.1 - 0.22 11.3 10.5 1 9.2 1.6 2.5 2 2 0 2 2 2 0 Double zinc ribbon LIM PF00412.17 KFM01403.1 - 0.34 11.0 13.4 1.8 8.6 1.3 3.5 1 1 2 3 3 3 0 LIM domain DNA_RNApol_7kD PF03604.8 KFM01403.1 - 0.34 10.4 16.1 2 7.9 0.8 4.1 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit DUF3268 PF11672.3 KFM01403.1 - 0.41 10.7 10.1 2.6 8.1 5.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3268) zinc_ribbon_4 PF13717.1 KFM01403.1 - 0.5 10.0 9.8 39 4.0 0.0 4.2 3 1 0 4 4 4 0 zinc-ribbon domain Gin PF10764.4 KFM01403.1 - 0.75 9.5 5.6 2 8.2 0.1 3.2 3 0 0 3 3 3 0 Inhibitor of sigma-G Gin PHD PF00628.24 KFM01403.1 - 0.88 9.3 13.4 8.3 6.1 3.5 3.3 1 1 1 2 2 2 0 PHD-finger Mut7-C PF01927.11 KFM01403.1 - 1.8 8.5 8.1 0.37 10.7 1.1 2.2 1 1 1 2 2 2 0 Mut7-C RNAse domain zinc-ribbons_6 PF07191.7 KFM01403.1 - 1.9 8.3 13.1 12 5.8 0.5 3.5 2 1 2 4 4 4 0 zinc-ribbons zf-RING_3 PF14369.1 KFM01403.1 - 2.2 8.3 11.4 3.6 7.6 0.1 3.9 4 0 0 4 4 4 0 zinc-finger zinc_ribbon_5 PF13719.1 KFM01403.1 - 2.3 7.8 12.3 35 4.0 0.0 4.1 3 1 0 3 3 3 0 zinc-ribbon domain Rep_fac-A_C PF08646.5 KFM01403.1 - 3 7.5 10.0 2.6 7.7 0.6 2.7 1 1 1 2 2 2 0 Replication factor-A C terminal domain C1_2 PF03107.11 KFM01403.1 - 3.1 8.0 16.0 1.5 8.9 0.5 4.0 4 0 0 4 4 4 0 C1 domain KRAB PF01352.22 KFM01404.1 - 5.6e-11 41.7 0.4 1.4e-10 40.3 0.3 1.8 1 0 0 1 1 1 1 KRAB box zf-H2C2_2 PF13465.1 KFM01406.1 - 1.1e-32 110.7 42.0 3e-10 39.8 0.1 7.1 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2 PF00096.21 KFM01406.1 - 9.7e-32 107.3 48.0 5.4e-07 29.5 1.1 6.2 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM01406.1 - 3.7e-18 64.4 47.8 0.00011 22.3 0.5 6.2 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM01406.1 - 7.7e-10 38.6 28.7 0.02 15.0 0.1 6.2 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM01406.1 - 2.5e-08 33.8 33.4 0.0027 17.8 0.5 5.9 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFM01406.1 - 1e-06 28.3 33.0 0.25 11.3 0.4 6.4 6 0 0 6 6 6 4 C2H2-type zinc finger Prok-RING_1 PF14446.1 KFM01406.1 - 3.8e-06 26.5 7.1 14 5.4 0.0 6.1 6 0 0 6 6 6 0 Prokaryotic RING finger family 1 zf-CHY PF05495.7 KFM01406.1 - 1.1e-05 25.4 19.4 0.0076 16.3 5.2 2.6 2 1 0 2 2 2 2 CHY zinc finger zf-Di19 PF05605.7 KFM01406.1 - 0.00033 20.7 30.3 0.37 10.9 4.7 4.8 1 1 3 5 5 5 4 Drought induced 19 protein (Di19), zinc-binding zf-RING_3 PF14369.1 KFM01406.1 - 0.00096 19.0 17.1 0.029 14.3 0.0 5.4 6 0 0 6 6 6 1 zinc-finger DZR PF12773.2 KFM01406.1 - 0.002 17.9 21.7 0.18 11.6 2.2 4.2 1 1 1 2 2 2 1 Double zinc ribbon zinc_ribbon_5 PF13719.1 KFM01406.1 - 0.0034 16.9 21.1 1.1 8.9 0.1 5.8 5 1 0 5 5 5 1 zinc-ribbon domain YhfH PF14149.1 KFM01406.1 - 0.0046 16.7 6.4 2.7 7.8 0.0 4.2 4 0 0 4 4 4 1 YhfH-like protein Zn_Tnp_IS1595 PF12760.2 KFM01406.1 - 0.0047 16.7 16.5 0.017 14.8 3.9 4.8 3 2 1 4 4 4 2 Transposase zinc-ribbon domain zf-C2HC_2 PF13913.1 KFM01406.1 - 0.01 15.4 5.9 0.076 12.6 0.5 4.9 5 1 0 5 5 3 0 zinc-finger of a C2HC-type zinc_ribbon_4 PF13717.1 KFM01406.1 - 0.01 15.5 21.6 1.4 8.6 0.1 5.9 5 1 0 5 5 5 0 zinc-ribbon domain FYDLN_acid PF09538.5 KFM01406.1 - 0.011 16.2 4.9 2.4 8.7 0.0 4.1 1 1 3 4 4 4 0 Protein of unknown function (FYDLN_acid) Zn-ribbon_8 PF09723.5 KFM01406.1 - 0.022 14.7 25.9 0.18 11.7 2.5 5.7 3 2 2 5 5 5 0 Zinc ribbon domain LIM PF00412.17 KFM01406.1 - 0.025 14.6 23.7 0.49 10.4 1.6 5.1 2 2 2 4 4 4 0 LIM domain zinc_ribbon_2 PF13240.1 KFM01406.1 - 0.031 13.7 1.6 0.031 13.7 1.1 4.1 5 1 0 5 5 3 0 zinc-ribbon domain C1_4 PF07975.7 KFM01406.1 - 0.044 13.7 24.0 0.34 10.9 0.4 4.9 1 1 4 5 5 5 0 TFIIH C1-like domain DUF2256 PF10013.4 KFM01406.1 - 0.09 12.5 19.7 0.19 11.5 0.4 5.7 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) BolA PF01722.13 KFM01406.1 - 0.095 12.6 5.0 3.7 7.5 0.0 3.1 2 1 1 3 3 3 0 BolA-like protein CpXC PF14353.1 KFM01406.1 - 0.11 12.4 21.8 7.4 6.5 0.6 5.4 2 2 1 4 4 4 0 CpXC protein zf-AN1 PF01428.11 KFM01406.1 - 0.12 12.2 28.0 0.77 9.6 1.6 6.1 6 0 0 6 6 6 0 AN1-like Zinc finger HTH_18 PF12833.2 KFM01406.1 - 0.14 12.2 1.8 3.7 7.7 0.0 3.0 3 1 0 3 3 2 0 Helix-turn-helix domain HypA PF01155.14 KFM01406.1 - 0.2 11.3 16.0 7.1 6.3 4.6 3.7 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-C3HC4_3 PF13920.1 KFM01406.1 - 0.35 10.5 20.1 4.5 7.0 2.8 4.1 3 2 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-ribbon_3 PF13248.1 KFM01406.1 - 0.48 9.7 0.1 0.24 10.6 0.3 5.1 6 0 0 6 6 5 0 zinc-ribbon domain DUF329 PF03884.9 KFM01406.1 - 0.49 10.0 14.5 7.6 6.1 0.1 5.2 6 0 0 6 6 6 0 Domain of unknown function (DUF329) zf-IS66 PF13005.2 KFM01406.1 - 0.49 10.4 17.3 31 4.6 0.0 6.0 6 0 0 6 6 6 0 zinc-finger binding domain of transposase IS66 Rad50_zn_hook PF04423.9 KFM01406.1 - 0.73 9.3 13.6 4.4 6.8 0.1 4.1 2 2 2 4 4 4 0 Rad50 zinc hook motif DUF2039 PF10217.4 KFM01406.1 - 1.1 9.2 15.0 1.7 8.7 4.2 3.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2039) zf-RING_5 PF14634.1 KFM01406.1 - 1.4 8.7 24.8 1.8 8.3 5.0 4.6 2 1 1 3 3 3 0 zinc-RING finger domain Elf1 PF05129.8 KFM01406.1 - 1.5 8.5 17.2 1.5 8.5 1.1 4.4 1 1 4 5 5 5 0 Transcription elongation factor Elf1 like Zn_ribbon_recom PF13408.1 KFM01406.1 - 4.8 7.5 24.3 0.28 11.4 2.3 3.9 2 2 1 3 3 3 0 Recombinase zinc beta ribbon domain DUF2225 PF09986.4 KFM01406.1 - 6.2 6.2 17.0 5.3 6.4 0.9 4.5 2 2 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) C1_2 PF03107.11 KFM01406.1 - 9 6.5 18.5 11 6.2 0.0 5.6 6 0 0 6 6 6 0 C1 domain GST_C_2 PF13410.1 KFM01408.1 - 0.016 15.0 18.2 3.5 7.5 0.5 5.2 1 1 4 5 5 5 0 Glutathione S-transferase, C-terminal domain Adeno_PX PF05829.7 KFM01408.1 - 0.045 13.2 2.4 3e+02 1.0 0.0 5.3 6 0 0 6 6 6 0 Adenovirus late L2 mu core protein (Protein X) zf-H2C2_2 PF13465.1 KFM01409.1 - 1.4e-96 312.3 53.9 2.4e-08 33.8 0.2 12.7 13 0 0 13 13 13 11 Zinc-finger double domain zf-C2H2 PF00096.21 KFM01409.1 - 3.7e-70 228.2 82.6 2.1e-06 27.6 0.5 12.2 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KFM01409.1 - 6.9e-40 133.7 79.9 1.5e-05 24.6 0.1 12.6 12 1 0 12 12 12 10 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KFM01409.1 - 1.2e-33 112.8 79.0 0.0039 17.4 0.3 12.1 12 0 0 12 12 12 11 C2H2-type zinc finger C1_4 PF07975.7 KFM01409.1 - 1.3e-21 76.3 37.3 0.0093 15.9 0.6 9.8 2 1 6 9 9 9 9 TFIIH C1-like domain DNA_RNApol_7kD PF03604.8 KFM01409.1 - 9.8e-17 60.1 40.4 0.35 10.3 0.0 12.1 12 0 0 12 12 12 10 DNA directed RNA polymerase, 7 kDa subunit zf-met PF12874.2 KFM01409.1 - 1.4e-13 50.4 67.5 0.4 10.9 0.6 10.8 11 0 0 11 11 10 8 Zinc-finger of C2H2 type zf-CHY PF05495.7 KFM01409.1 - 2.7e-10 40.2 43.4 0.0031 17.6 3.7 5.8 1 1 6 7 7 7 6 CHY zinc finger CpXC PF14353.1 KFM01409.1 - 2.6e-07 30.6 33.4 3.9 7.4 0.0 11.4 12 0 0 12 12 12 1 CpXC protein Elf1 PF05129.8 KFM01409.1 - 7.1e-07 28.8 37.9 0.15 11.7 0.7 7.4 1 1 9 10 10 10 9 Transcription elongation factor Elf1 like zinc_ribbon_5 PF13719.1 KFM01409.1 - 2.3e-06 27.0 44.8 5.7 6.6 1.3 11.4 10 2 0 10 10 10 0 zinc-ribbon domain RRN7 PF11781.3 KFM01409.1 - 3.2e-06 26.5 35.8 15 5.1 0.1 11.7 12 0 0 12 12 12 0 RNA polymerase I-specific transcription initiation factor Rrn7 Baculo_IE-1 PF05290.6 KFM01409.1 - 3.3e-05 23.6 19.4 20 4.8 0.1 8.3 1 1 8 9 9 9 0 Baculovirus immediate-early protein (IE-0) zf-C2H2_jaz PF12171.3 KFM01409.1 - 0.00034 20.6 42.1 17 5.7 0.0 11.8 12 0 0 12 12 12 0 Zinc-finger double-stranded RNA-binding zf-RING_2 PF13639.1 KFM01409.1 - 0.00087 19.0 33.4 47 3.9 0.0 10.1 9 2 1 10 10 10 0 Ring finger domain Scramblase PF03803.10 KFM01409.1 - 0.0016 17.5 14.7 1.2 8.2 0.7 4.3 1 1 5 6 6 6 4 Scramblase zinc-ribbons_6 PF07191.7 KFM01409.1 - 0.017 14.9 42.3 29 4.5 0.1 10.8 3 3 7 10 10 10 0 zinc-ribbons Protoglobin PF11563.3 KFM01409.1 - 0.093 12.3 0.0 65 3.1 0.0 3.2 2 1 2 4 4 4 0 Protoglobin Zn-ribbon_8 PF09723.5 KFM01409.1 - 0.2 11.6 53.4 3 7.8 0.1 10.7 3 2 9 12 12 12 0 Zinc ribbon domain YhfH PF14149.1 KFM01409.1 - 0.23 11.2 10.1 37 4.2 0.3 4.9 4 0 0 4 4 4 0 YhfH-like protein zf-AN1 PF01428.11 KFM01409.1 - 0.33 10.8 53.3 1.3 8.9 0.5 11.8 10 1 2 12 12 12 0 AN1-like Zinc finger Fer4_16 PF13484.1 KFM01409.1 - 0.5 11.1 34.1 1.1e+02 3.6 0.0 9.5 9 2 0 9 9 9 0 4Fe-4S double cluster binding domain Zn_Tnp_IS1595 PF12760.2 KFM01409.1 - 0.69 9.7 59.6 0.6 9.9 1.7 9.7 9 2 0 10 10 10 0 Transposase zinc-ribbon domain C1_2 PF03107.11 KFM01409.1 - 1.1 9.4 39.1 50 4.1 0.0 9.8 12 0 0 12 12 11 0 C1 domain NinF PF05810.7 KFM01409.1 - 1.4 8.7 7.6 2.3 8.0 0.1 4.3 3 1 1 4 4 3 0 NinF protein zinc_ribbon_4 PF13717.1 KFM01409.1 - 1.7 8.3 59.4 5.9 6.6 1.3 11.2 3 2 7 10 10 10 0 zinc-ribbon domain zf-C4_ClpX PF06689.8 KFM01409.1 - 4.1 7.0 10.0 8.1 6.0 1.5 4.9 3 1 0 3 3 3 0 ClpX C4-type zinc finger DUF2256 PF10013.4 KFM01409.1 - 6.8 6.5 41.0 1.1e+02 2.7 0.1 11.3 12 0 0 12 12 12 0 Uncharacterized protein conserved in bacteria (DUF2256) BolA PF01722.13 KFM01409.1 - 6.9 6.6 14.8 81 3.2 0.6 5.4 2 1 3 5 5 4 0 BolA-like protein Zn_ribbon_recom PF13408.1 KFM01409.1 - 7 6.9 45.4 15 5.9 2.1 7.9 1 1 3 4 4 3 0 Recombinase zinc beta ribbon domain UPF0547 PF10571.4 KFM01409.1 - 8 6.2 12.5 20 4.9 0.1 5.4 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 WD40 PF00400.27 KFM01411.1 - 7.3e-33 111.2 12.2 1.1e-13 50.4 1.1 4.3 4 0 0 4 4 4 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KFM01411.1 - 0.057 12.1 0.0 7.2 5.2 0.0 2.3 1 1 0 2 2 2 0 Nup133 N terminal like Apc4_WD40 PF12894.2 KFM01411.1 - 0.13 11.8 0.0 0.39 10.2 0.0 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Sec63 PF02889.11 KFM01412.1 - 9.9e-24 84.1 0.2 1.8e-23 83.2 0.0 1.5 2 0 0 2 2 2 1 Sec63 Brl domain DUF603 PF04645.7 KFM01412.1 - 0.012 15.5 0.2 0.015 15.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF603 DUF4391 PF14335.1 KFM01412.1 - 0.023 14.0 0.1 0.032 13.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) Peptidase_C39 PF03412.10 KFM01412.1 - 0.047 13.4 0.0 0.057 13.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase C39 family Sema PF01403.14 KFM01413.1 - 3.3e-35 121.4 0.0 3.6e-35 121.3 0.0 1.0 1 0 0 1 1 1 1 Sema domain DUF21 PF01595.15 KFM01414.1 - 5.3e-28 97.5 0.0 7.5e-28 97.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 KFM01414.1 - 3.5e-10 39.5 0.3 0.00014 21.5 0.0 2.8 2 0 0 2 2 2 2 CBS domain cNMP_binding PF00027.24 KFM01414.1 - 0.009 15.8 0.0 0.27 11.0 0.0 2.3 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Nrf1_DNA-bind PF10491.4 KFM01414.1 - 0.045 12.9 0.0 0.08 12.0 0.0 1.3 1 0 0 1 1 1 0 NLS-binding and DNA-binding and dimerisation domains of Nrf1 Lectin_leg-like PF03388.8 KFM01416.1 - 5.3e-66 222.0 0.0 6.2e-66 221.8 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family PMP1_2 PF08114.6 KFM01416.1 - 0.0095 15.4 0.2 0.017 14.6 0.1 1.4 1 0 0 1 1 1 1 ATPase proteolipid family Col_cuticle_N PF01484.12 KFM01416.1 - 0.1 12.2 1.5 0.17 11.6 1.0 1.3 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain Vpu PF00558.14 KFM01416.1 - 0.19 11.3 0.6 0.34 10.4 0.4 1.4 1 0 0 1 1 1 0 Vpu protein Abhydrolase_5 PF12695.2 KFM01418.1 - 4.6e-08 32.9 0.0 1.1e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFM01418.1 - 0.01 15.6 0.5 1.6 8.5 0.1 3.1 2 1 1 3 3 3 0 Alpha/beta hydrolase family EB1_binding PF05937.6 KFM01419.1 - 0.035 14.4 5.7 0.052 13.9 4.0 1.3 1 0 0 1 1 1 0 EB-1 Binding Domain Pkinase PF00069.20 KFM01421.1 - 8.9e-31 106.9 0.0 9.7e-31 106.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM01421.1 - 3.2e-20 72.3 0.0 3.6e-20 72.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM01421.1 - 1.3e-05 24.2 0.0 1.5e-05 24.1 0.0 1.0 1 0 0 1 1 1 1 Kinase-like Cnd2 PF05786.9 KFM01422.1 - 1.1e-15 57.3 0.1 1.1e-15 57.3 0.1 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 7tm_1 PF00001.16 KFM01423.1 - 3e-62 210.1 22.5 4e-62 209.6 15.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM01423.1 - 5.5e-08 32.2 21.1 7.3e-08 31.8 14.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Tetraspannin PF00335.15 KFM01424.1 - 6.8e-35 120.3 9.4 8.9e-35 119.9 6.5 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF2371 PF10177.4 KFM01424.1 - 0.63 9.9 2.7 3 7.7 0.2 2.6 2 1 1 3 3 3 0 Uncharacterised conserved protein (DUF2371) DUF4064 PF13273.1 KFM01424.1 - 1.3 9.2 13.2 2.7 8.1 0.9 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) ABC2_membrane_3 PF12698.2 KFM01424.1 - 1.5 7.7 12.3 4.2 6.2 6.2 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF1129 PF06570.6 KFM01424.1 - 4.8 6.4 7.4 8.6 5.6 3.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) HCO3_cotransp PF00955.16 KFM01425.1 - 1.9e-238 792.2 9.3 2.3e-238 791.9 6.5 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.8 KFM01425.1 - 3.5e-96 321.6 0.0 5.2e-96 321.0 0.0 1.3 1 0 0 1 1 1 1 Band 3 cytoplasmic domain Xan_ur_permease PF00860.15 KFM01425.1 - 0.27 9.6 15.5 0.028 12.9 0.6 2.9 3 0 0 3 3 3 0 Permease family THF_DHG_CYH_C PF02882.14 KFM01426.1 - 1.3e-63 212.8 2.6 2.1e-63 212.1 1.8 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 KFM01426.1 - 1.6e-39 134.5 0.1 2.3e-39 134.0 0.1 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Mob1_phocein PF03637.12 KFM01427.1 - 2e-82 275.0 0.3 2.3e-82 274.8 0.2 1.0 1 0 0 1 1 1 1 Mob1/phocein family SIM_C PF06621.7 KFM01428.1 - 4.3e-122 407.2 19.4 6e-122 406.8 13.5 1.2 1 0 0 1 1 1 1 Single-minded protein C-terminus PAS_3 PF08447.6 KFM01428.1 - 6.5e-11 42.1 0.0 9.6e-10 38.4 0.0 2.7 3 0 0 3 3 3 1 PAS fold PAS PF00989.19 KFM01428.1 - 2.9e-10 39.9 0.0 5.3e-05 22.9 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.1 KFM01428.1 - 3.1e-08 33.5 0.2 2.4e-07 30.6 0.0 2.5 3 0 0 3 3 3 1 PAS domain HLH PF00010.21 KFM01428.1 - 2e-06 27.3 0.9 3.5e-05 23.3 0.5 2.5 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain RVT_1 PF00078.22 KFM01432.1 - 2.4e-13 49.9 0.0 4.6e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HECT PF00632.20 KFM01435.1 - 2.5e-93 312.7 0.1 1.2e-92 310.5 0.0 1.9 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Ank_2 PF12796.2 KFM01435.1 - 2.8e-70 232.6 10.9 5.8e-21 74.6 0.8 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KFM01435.1 - 1e-40 135.5 10.1 1.1e-08 34.4 0.0 7.4 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 KFM01435.1 - 3.4e-34 116.6 4.8 1.3e-11 44.7 0.1 5.9 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM01435.1 - 1.4e-31 105.3 1.9 5.5e-07 29.2 0.0 7.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 KFM01435.1 - 1.8e-28 97.9 8.4 7.3e-11 41.9 0.1 5.0 2 2 2 4 4 4 4 Ankyrin repeats (many copies) CSD PF00313.17 KFM01436.1 - 6.6e-18 64.2 0.1 1.4e-17 63.2 0.1 1.6 1 1 0 1 1 1 1 'Cold-shock' DNA-binding domain zf-CCHC PF00098.18 KFM01436.1 - 5.8e-07 29.1 14.7 0.00045 20.0 2.6 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 KFM01436.1 - 0.00086 18.9 11.1 0.07 12.8 1.5 2.5 2 0 0 2 2 2 2 Zinc knuckle DUF2946 PF11162.3 KFM01436.1 - 0.042 14.0 0.9 0.1 12.8 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) Peptidase_S9_N PF02897.10 KFM01437.1 - 6.2e-145 482.8 0.0 7.5e-145 482.6 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 KFM01437.1 - 2.4e-69 232.7 0.0 4e-69 232.0 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 KFM01437.1 - 0.056 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative esterase zf-H2C2_2 PF13465.1 KFM01438.1 - 4.4e-28 96.1 46.9 4.4e-08 33.0 0.9 5.7 5 0 0 5 5 5 5 Zinc-finger double domain zf-C2H2 PF00096.21 KFM01438.1 - 2.6e-14 52.5 50.4 3e-05 24.1 0.3 5.7 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM01438.1 - 4.7e-13 48.4 42.0 0.0017 18.5 1.3 5.7 5 0 0 5 5 5 4 C2H2-type zinc finger SET PF00856.23 KFM01438.1 - 2.3e-08 34.5 0.1 1.2e-07 32.1 0.1 2.2 1 1 0 1 1 1 1 SET domain zf-C2H2_6 PF13912.1 KFM01438.1 - 2.1e-05 24.2 6.7 0.00034 20.4 1.2 5.3 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM01438.1 - 0.00012 22.1 30.9 0.0028 17.7 0.3 5.0 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM01438.1 - 0.0073 16.4 38.5 0.036 14.2 2.2 5.7 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-BED PF02892.10 KFM01438.1 - 5.2 6.9 35.4 0.23 11.2 5.2 4.8 4 1 1 5 5 5 0 BED zinc finger ADH_zinc_N_2 PF13602.1 KFM01440.1 - 1.9e-22 80.4 0.0 3.1e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KFM01440.1 - 2.7e-14 52.8 0.1 4.8e-14 52.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFM01440.1 - 6.1e-10 38.8 0.0 1.7e-09 37.3 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.16 KFM01440.1 - 0.0098 15.4 0.1 0.015 14.8 0.1 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_10 PF13460.1 KFM01440.1 - 0.011 15.6 0.1 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KFM01440.1 - 0.016 15.0 0.6 0.033 13.9 0.4 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 KFM01440.1 - 0.039 13.0 0.0 0.069 12.2 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Amidase PF01425.16 KFM01441.1 - 7.8e-126 420.4 0.0 4.6e-125 417.9 0.0 1.8 1 1 0 1 1 1 1 Amidase FAM176 PF14851.1 KFM01442.1 - 0.042 13.5 1.4 0.068 12.8 1.0 1.3 1 0 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.5 KFM01442.1 - 0.42 10.8 7.3 0.86 9.8 5.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 KFM01442.1 - 3.2 8.1 8.5 7.3 6.9 5.9 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BEN PF10523.4 KFM01443.1 - 1.1e-71 236.8 6.0 1.1e-18 67.0 0.1 4.6 4 0 0 4 4 4 4 BEN domain DUF1826 PF08856.6 KFM01443.1 - 0.023 14.4 0.6 1.9 8.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1826) polyprenyl_synt PF00348.12 KFM01444.1 - 1.2e-14 53.8 0.1 2.2e-14 52.9 0.1 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase ORF6C PF10552.4 KFM01444.1 - 0.16 11.7 0.0 0.69 9.6 0.0 2.0 2 0 0 2 2 2 0 ORF6C domain SOBP PF15279.1 KFM01445.1 - 4.3e-78 263.7 36.3 4.3e-78 263.7 25.2 3.3 3 0 0 3 3 3 1 Sine oculis-binding protein zf-FCS PF06467.9 KFM01445.1 - 0.00068 19.2 13.9 0.062 12.9 2.0 2.7 2 0 0 2 2 2 2 MYM-type Zinc finger with FCS sequence motif DUF3588 PF12140.3 KFM01446.1 - 3.8e-44 149.5 0.6 5.5e-44 149.0 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3588) SAM_1 PF00536.25 KFM01446.1 - 3.6e-14 52.6 0.1 6.8e-14 51.7 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFM01446.1 - 0.00031 20.5 0.0 0.00057 19.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 KFM01446.1 - 0.0082 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Sec63 PF02889.11 KFM01447.1 - 5.1e-52 177.0 4.9 6.1e-44 150.5 0.6 2.1 2 0 0 2 2 2 2 Sec63 Brl domain DnaJ PF00226.26 KFM01447.1 - 3.2e-19 68.4 0.1 9.2e-19 66.9 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain Pkinase PF00069.20 KFM01448.1 - 3.8e-63 213.0 0.0 5.1e-63 212.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM01448.1 - 1.3e-31 109.5 0.0 2.2e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Activin_recp PF01064.18 KFM01448.1 - 3.6e-08 33.9 11.1 3.6e-08 33.9 7.7 2.4 2 0 0 2 2 2 1 Activin types I and II receptor domain APH PF01636.18 KFM01448.1 - 0.041 13.6 0.1 0.07 12.8 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PWWP PF00855.12 KFM01449.1 - 0.00057 20.0 0.1 0.0018 18.4 0.1 1.9 1 1 0 1 1 1 1 PWWP domain MBD PF01429.14 KFM01449.1 - 0.039 13.4 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 Methyl-CpG binding domain E_Pc_C PF06752.7 KFM01450.1 - 2.6e-94 315.0 27.2 4.2e-94 314.3 18.8 1.4 1 0 0 1 1 1 1 Enhancer of Polycomb C-terminus EPL1 PF10513.4 KFM01450.1 - 5.8e-32 111.1 2.8 5.8e-32 111.1 1.9 3.7 3 1 0 3 3 3 1 Enhancer of polycomb-like Guanylate_cyc PF00211.15 KFM01451.1 - 5.4e-130 430.0 0.4 1.8e-66 223.0 0.1 2.2 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.9 KFM01451.1 - 0.02 14.1 0.9 2.9 7.0 0.1 2.4 2 0 0 2 2 2 0 Heme NO binding associated DUF1053 PF06327.9 KFM01451.1 - 0.056 13.7 0.8 0.13 12.6 0.5 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1053) Thyroglobulin_1 PF00086.13 KFM01453.1 - 1.8e-21 75.2 3.3 3.6e-21 74.2 2.3 1.5 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat RVT_1 PF00078.22 KFM01454.1 - 0.0034 16.7 0.0 0.0053 16.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mito_fiss_reg PF05308.6 KFM01455.1 - 7.5e-85 284.3 4.4 1.4e-84 283.4 3.0 1.4 1 0 0 1 1 1 1 Mitochondrial fission regulator FlxA PF14282.1 KFM01455.1 - 0.62 10.0 4.9 0.1 12.5 0.4 2.0 2 0 0 2 2 2 0 FlxA-like protein Arm PF00514.18 KFM01456.1 - 2.3e-05 24.0 0.0 5e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Armadillo/beta-catenin-like repeat HMA PF00403.21 KFM01456.1 - 0.0023 18.0 0.3 0.0048 17.0 0.2 1.6 1 0 0 1 1 1 1 Heavy-metal-associated domain HEAT_2 PF13646.1 KFM01456.1 - 0.062 13.5 0.1 0.2 11.9 0.0 1.9 1 0 0 1 1 1 0 HEAT repeats p450 PF00067.17 KFM01457.1 - 6.1e-48 163.4 0.8 8.7e-48 162.9 0.5 1.1 1 0 0 1 1 1 1 Cytochrome P450 YTH PF04146.10 KFM01458.1 - 1.1e-47 161.1 0.1 1.6e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 YT521-B-like domain Channel_Tsx PF03502.8 KFM01458.1 - 0.015 15.1 0.1 0.026 14.3 0.1 1.3 1 0 0 1 1 1 0 Nucleoside-specific channel-forming protein, Tsx PAT1 PF09770.4 KFM01458.1 - 9.1 4.3 26.8 13 3.8 18.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CRAL_TRIO PF00650.15 KFM01459.1 - 1.4e-32 112.3 0.0 1.8e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 KFM01459.1 - 0.08 12.8 0.0 0.092 12.6 0.0 1.2 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Peptidase_C26 PF07722.8 KFM01460.1 - 3.6e-39 134.4 0.0 5e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase C26 GATase PF00117.23 KFM01460.1 - 6.6e-10 38.7 0.0 1e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NKAIN PF05640.9 KFM01461.1 - 3.6e-73 244.8 6.0 4e-73 244.6 4.2 1.0 1 0 0 1 1 1 1 Na,K-Atpase Interacting protein DUF1003 PF06210.6 KFM01461.1 - 0.024 14.5 0.3 0.032 14.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Asp_Arg_Hydrox PF05118.10 KFM01463.1 - 2.4e-61 206.3 0.2 3.8e-61 205.6 0.1 1.3 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Asp-B-Hydro_N PF05279.6 KFM01463.1 - 8.4e-53 179.6 0.4 8.4e-53 179.6 0.3 2.0 1 1 1 2 2 2 1 Aspartyl beta-hydroxylase N-terminal region TPR_11 PF13414.1 KFM01463.1 - 1.1e-14 53.8 1.3 0.0018 17.9 0.2 4.4 4 1 0 4 4 4 3 TPR repeat TPR_16 PF13432.1 KFM01463.1 - 2e-11 44.2 1.4 1.2e-05 25.8 0.4 4.1 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFM01463.1 - 4.8e-09 36.0 0.0 0.0011 19.4 0.1 5.1 3 1 3 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFM01463.1 - 6.2e-09 35.7 5.2 0.016 15.5 0.1 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFM01463.1 - 1.6e-08 33.8 6.6 0.029 14.2 0.0 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFM01463.1 - 4.2e-07 29.2 0.7 0.11 12.2 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFM01463.1 - 1.5e-06 28.4 0.3 0.0064 16.7 0.1 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFM01463.1 - 2.5e-06 26.8 1.9 0.17 11.5 0.0 6.2 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFM01463.1 - 4e-05 23.4 0.4 5.4 7.0 0.1 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFM01463.1 - 0.00011 22.1 0.2 7.6 7.0 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat YfiO PF13525.1 KFM01463.1 - 0.01 15.2 0.4 0.098 12.1 0.3 2.5 2 1 0 2 2 2 0 Outer membrane lipoprotein BTAD PF03704.12 KFM01463.1 - 0.066 13.5 0.0 1.7 8.9 0.0 2.4 2 0 0 2 2 2 0 Bacterial transcriptional activator domain TPR_9 PF13371.1 KFM01463.1 - 0.12 12.2 0.0 30 4.5 0.0 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat LUC7 PF03194.10 KFM01463.1 - 0.56 9.6 4.2 0.097 12.1 0.2 1.6 2 0 0 2 2 2 0 LUC7 N_terminus Longin PF13774.1 KFM01465.1 - 9.9e-17 60.2 0.0 1.2e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Regulated-SNARE-like domain Hexokinase_2 PF03727.11 KFM01466.1 - 1.7e-94 315.5 0.1 2.4e-94 315.1 0.1 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KFM01466.1 - 1.1e-64 217.6 0.5 1.1e-31 109.7 0.0 2.2 1 1 1 2 2 2 2 Hexokinase DNA_pol_E_B PF04042.11 KFM01467.1 - 2.7e-52 177.0 0.0 4.7e-52 176.2 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Peptidase_M14 PF00246.19 KFM01468.1 - 9.2e-64 215.7 0.0 1.2e-63 215.3 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.1 KFM01468.1 - 5.5e-13 48.7 0.0 8.7e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 KFM01468.1 - 2.2e-05 24.4 0.0 4.7e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4480) phage_tail_N PF08400.5 KFM01468.1 - 0.0089 15.7 0.2 0.048 13.3 0.1 1.9 1 1 0 1 1 1 1 Prophage tail fibre N-terminal Peptidase_C14 PF00656.17 KFM01469.1 - 2.4e-23 83.0 0.0 2.8e-23 82.9 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Antimicrobial_6 PF08036.6 KFM01469.1 - 0.0093 15.7 4.9 0.12 12.1 0.2 2.6 2 0 0 2 2 2 2 Diapausin family of antimicrobial peptide PXB PF12828.2 KFM01469.1 - 0.014 15.0 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 PX-associated GMC_oxred_N PF00732.14 KFM01470.1 - 0.064 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 GMC oxidoreductase ELMO_CED12 PF04727.8 KFM01471.1 - 3.3e-13 49.5 0.0 1.5e-05 24.6 0.0 2.1 1 1 1 2 2 2 2 ELMO/CED-12 family 7tm_1 PF00001.16 KFM01472.1 - 1e-75 254.2 0.1 1.2e-75 253.9 0.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM01472.1 - 9.1e-10 38.1 4.3 6.5e-09 35.3 3.0 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM01472.1 - 4.5e-07 29.2 4.9 4.5e-07 29.2 3.4 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Herpes_US9 PF06072.6 KFM01472.1 - 3.4 7.5 6.9 1.1 9.1 0.0 3.3 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 DUF2061 PF09834.4 KFM01472.1 - 8.1 6.7 7.3 12 6.2 2.0 2.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2061) BTB PF00651.26 KFM01473.1 - 1.3e-25 89.5 1.2 2.1e-25 88.8 0.8 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 KFM01473.1 - 1.6e-14 53.3 22.2 9.7e-10 38.2 1.2 3.9 4 0 0 4 4 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM01473.1 - 2.1e-09 37.0 15.8 1.5e-05 24.9 0.8 4.0 3 0 0 3 3 3 2 C2H2-type zinc finger DUF3342 PF11822.3 KFM01473.1 - 1.2e-06 27.9 0.3 1.2e-06 27.9 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) zf-C2H2 PF00096.21 KFM01473.1 - 2.3e-05 24.4 26.7 4.9e-05 23.4 1.5 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-met PF12874.2 KFM01473.1 - 0.011 15.9 0.1 0.011 15.9 0.1 4.2 4 0 0 4 4 3 0 Zinc-finger of C2H2 type zf-Di19 PF05605.7 KFM01473.1 - 0.19 11.8 18.6 0.12 12.5 5.1 3.8 2 1 1 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding Rubredoxin PF00301.15 KFM01473.1 - 0.21 11.5 2.7 32 4.4 0.2 3.6 3 0 0 3 3 3 0 Rubredoxin zf-C2H2_jaz PF12171.3 KFM01473.1 - 0.24 11.5 15.2 0.4 10.8 0.0 4.5 3 1 0 3 3 2 0 Zinc-finger double-stranded RNA-binding zf-met2 PF12907.2 KFM01473.1 - 0.74 9.8 0.0 0.74 9.8 0.0 3.2 4 0 0 4 4 3 0 Zinc-binding DUF4428 PF14471.1 KFM01473.1 - 2.2 8.0 8.3 0.12 12.0 0.4 2.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4428) zf-CHY PF05495.7 KFM01473.1 - 6.2 7.0 15.6 4.9 7.3 8.1 2.7 2 1 0 2 2 2 0 CHY zinc finger Spectrin PF00435.16 KFM01474.1 - 6e-65 216.1 24.9 6.7e-18 64.9 0.3 4.0 4 0 0 4 4 4 4 Spectrin repeat Gp-FAR-1 PF05823.7 KFM01474.1 - 0.00039 20.4 1.7 1.1 9.1 0.1 3.2 1 1 1 3 3 3 2 Nematode fatty acid retinoid binding protein (Gp-FAR-1) PilJ PF13675.1 KFM01474.1 - 0.021 15.1 8.3 0.87 9.9 0.1 4.0 4 1 1 5 5 5 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4081 PF13312.1 KFM01474.1 - 0.022 14.6 0.7 0.074 12.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4081) DUF948 PF06103.6 KFM01474.1 - 2.3 8.1 6.8 5.3 6.9 0.1 4.1 4 2 1 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF1192 PF06698.6 KFM01474.1 - 5.4 6.9 6.3 4.2 7.2 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) Sprouty PF05210.8 KFM01475.1 - 3.6e-40 136.3 24.3 3.6e-40 136.3 16.9 2.0 3 0 0 3 3 3 1 Sprouty protein (Spry) WH1 PF00568.18 KFM01475.1 - 9.5e-11 41.4 0.0 1.6e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 WH1 domain DUF2465 PF10239.4 KFM01476.1 - 1.2e-129 432.1 0.0 1.4e-129 431.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2465) RasGEF PF00617.14 KFM01477.1 - 9.7e-48 162.3 0.2 1.9e-47 161.4 0.1 1.5 1 0 0 1 1 1 1 RasGEF domain C1_1 PF00130.17 KFM01477.1 - 3e-14 52.4 8.0 7.1e-14 51.2 5.5 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RasGEF_N PF00618.15 KFM01477.1 - 9.4e-09 35.3 1.4 9.4e-09 35.3 1.0 2.4 3 0 0 3 3 3 1 RasGEF N-terminal motif EF-hand_7 PF13499.1 KFM01477.1 - 2.5e-08 33.9 0.2 6.8e-06 26.1 0.0 3.6 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_6 PF13405.1 KFM01477.1 - 1.2e-05 24.8 0.0 7.3e-05 22.3 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 KFM01477.1 - 2.6e-05 23.2 2.9 3.3e-05 22.8 0.1 2.7 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.1 KFM01477.1 - 0.00026 20.1 1.4 0.00099 18.3 0.0 2.6 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.1 KFM01477.1 - 0.022 14.3 1.1 0.11 12.0 0.1 2.7 3 0 0 3 3 3 0 EF-hand domain pair Secretogranin_V PF05281.6 KFM01478.1 - 5.3e-70 235.0 4.0 8.8e-69 231.0 2.8 1.9 1 1 0 1 1 1 1 Neuroendocrine protein 7B2 precursor (Secretogranin V) DAN PF03045.10 KFM01479.1 - 5.7e-43 145.2 8.6 7.5e-43 144.8 6.0 1.2 1 0 0 1 1 1 1 DAN domain Neurensin PF14927.1 KFM01479.1 - 0.036 13.4 0.0 0.099 12.0 0.0 1.7 2 0 0 2 2 2 0 Neurensin DUF2602 PF10782.4 KFM01479.1 - 2 8.3 8.0 6.5 6.6 0.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2602) Filament PF00038.16 KFM01482.1 - 1.6e-110 369.4 29.5 1.9e-110 369.2 20.5 1.0 1 0 0 1 1 1 1 Intermediate filament protein AAA_13 PF13166.1 KFM01482.1 - 0.00059 18.4 15.8 0.00059 18.4 11.0 1.4 2 0 0 2 2 2 1 AAA domain BRE1 PF08647.6 KFM01482.1 - 0.0026 17.6 2.2 0.0026 17.6 1.6 4.2 3 2 2 5 5 4 1 BRE1 E3 ubiquitin ligase Vps51 PF08700.6 KFM01482.1 - 0.0034 17.1 3.1 2 8.3 0.4 3.4 3 0 0 3 3 3 1 Vps51/Vps67 MscS_porin PF12795.2 KFM01482.1 - 0.0083 15.4 4.9 0.0083 15.4 3.4 2.7 3 0 0 3 3 3 1 Mechanosensitive ion channel porin domain Taxilin PF09728.4 KFM01482.1 - 0.017 14.2 20.2 0.017 14.1 3.4 2.9 1 1 2 3 3 3 0 Myosin-like coiled-coil protein ATG16 PF08614.6 KFM01482.1 - 0.021 14.6 20.0 0.37 10.5 2.5 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) bZIP_1 PF00170.16 KFM01482.1 - 0.022 14.6 0.2 0.022 14.6 0.2 4.6 5 1 0 5 5 4 0 bZIP transcription factor Myosin_tail_1 PF01576.14 KFM01482.1 - 0.028 12.1 32.8 0.1 10.3 8.1 3.0 2 1 1 3 3 3 0 Myosin tail Tropomyosin_1 PF12718.2 KFM01482.1 - 0.03 14.1 29.0 0.077 12.8 6.6 3.6 3 1 0 3 3 3 0 Tropomyosin like IncA PF04156.9 KFM01482.1 - 0.073 12.6 31.3 0.067 12.7 5.6 3.9 2 1 2 4 4 4 0 IncA protein DUF2681 PF10883.3 KFM01482.1 - 0.16 12.2 3.1 1.5 9.0 0.1 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Fib_alpha PF08702.5 KFM01482.1 - 0.16 12.0 18.3 0.081 13.0 0.6 3.1 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family COG5 PF10392.4 KFM01482.1 - 0.23 11.4 6.9 0.12 12.3 2.2 2.3 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Reo_sigmaC PF04582.7 KFM01482.1 - 0.24 10.5 9.9 2.1 7.4 0.7 3.0 1 1 2 3 3 3 0 Reovirus sigma C capsid protein FlxA PF14282.1 KFM01482.1 - 0.47 10.4 13.0 1.8 8.5 1.4 3.3 2 1 0 2 2 2 0 FlxA-like protein FliJ PF02050.11 KFM01482.1 - 0.55 10.2 24.7 0.032 14.2 2.2 4.2 3 1 1 4 4 4 0 Flagellar FliJ protein CENP-F_leu_zip PF10473.4 KFM01482.1 - 0.61 9.9 30.4 0.32 10.8 0.4 4.6 3 1 2 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.6 KFM01482.1 - 0.67 9.8 12.6 1.4 8.8 1.0 4.7 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) DUF4140 PF13600.1 KFM01482.1 - 1.1 9.7 17.7 0.27 11.7 0.9 4.5 4 1 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) DUF948 PF06103.6 KFM01482.1 - 1.1 9.1 12.4 0.78 9.6 0.2 4.0 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) TPR_MLP1_2 PF07926.7 KFM01482.1 - 1.5 8.6 35.6 0.048 13.4 2.3 3.8 3 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein Phage_GP20 PF06810.6 KFM01482.1 - 2.5 7.5 22.3 0.022 14.2 4.0 3.4 2 1 1 3 3 3 0 Phage minor structural protein GP20 Baculo_PEP_C PF04513.7 KFM01482.1 - 2.9 7.7 14.3 0.87 9.4 1.0 3.9 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Zein-binding PF04576.10 KFM01482.1 - 3.4 7.8 22.7 1.3 9.2 0.5 3.4 3 1 0 3 3 2 0 Zein-binding TBPIP PF07106.8 KFM01482.1 - 3.6 7.1 26.4 0.4 10.2 3.0 4.2 2 1 3 5 5 5 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Bap31 PF05529.7 KFM01482.1 - 3.7 6.9 13.2 0.029 13.8 0.7 2.7 3 1 0 3 3 2 0 B-cell receptor-associated protein 31-like WXG100 PF06013.7 KFM01482.1 - 4 7.4 7.4 13 5.9 1.0 3.9 4 1 0 4 4 2 0 Proteins of 100 residues with WXG DASH_Duo1 PF08651.5 KFM01482.1 - 4.5 6.9 8.5 1.5 8.4 0.8 3.2 3 0 0 3 3 3 0 DASH complex subunit Duo1 Mnd1 PF03962.10 KFM01482.1 - 5.2 6.7 24.9 0.18 11.4 4.4 3.4 1 1 3 4 4 4 0 Mnd1 family Spc24 PF08286.6 KFM01482.1 - 5.7 6.6 22.0 0.49 10.0 0.3 4.5 4 1 1 5 5 5 0 Spc24 subunit of Ndc80 ADIP PF11559.3 KFM01482.1 - 5.9 6.7 25.5 1.2 8.9 4.4 4.1 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding COG2 PF06148.6 KFM01482.1 - 7.4 6.4 19.5 1.7 8.5 0.7 4.1 3 2 2 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 DivIC PF04977.10 KFM01482.1 - 8.3 5.9 26.5 1.8 8.1 1.1 5.7 4 2 2 6 6 6 0 Septum formation initiator Filament PF00038.16 KFM01483.1 - 1.5e-102 343.2 38.8 1.7e-102 343.0 26.9 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 KFM01483.1 - 2.5e-05 24.0 36.2 0.0015 18.2 1.5 3.5 4 0 0 4 4 4 2 TPR/MLP1/MLP2-like protein Myosin_tail_1 PF01576.14 KFM01483.1 - 0.0001 20.2 30.3 0.0001 20.2 21.0 2.3 1 1 1 2 2 2 1 Myosin tail ATG16 PF08614.6 KFM01483.1 - 0.00081 19.2 28.1 0.056 13.2 3.4 2.4 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Fib_alpha PF08702.5 KFM01483.1 - 0.013 15.6 1.9 0.013 15.6 1.3 3.3 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family bZIP_1 PF00170.16 KFM01483.1 - 0.019 14.8 1.0 0.019 14.8 0.7 4.9 4 1 1 5 5 5 0 bZIP transcription factor Tropomyosin_1 PF12718.2 KFM01483.1 - 0.023 14.5 33.9 0.018 14.8 10.8 3.2 3 1 0 3 3 3 0 Tropomyosin like FlaC_arch PF05377.6 KFM01483.1 - 0.024 14.5 1.8 0.024 14.5 1.2 4.9 5 1 0 6 6 6 0 Flagella accessory protein C (FlaC) Reo_sigmaC PF04582.7 KFM01483.1 - 0.031 13.4 1.6 15 4.6 0.3 2.9 1 1 2 3 3 3 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 KFM01483.1 - 0.057 11.8 22.9 0.1 11.0 15.0 2.0 1 1 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.7 KFM01483.1 - 0.087 12.6 12.4 5.4 6.8 2.9 4.0 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ADIP PF11559.3 KFM01483.1 - 0.14 12.0 30.2 0.3 11.0 8.2 3.2 2 2 1 3 3 3 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.4 KFM01483.1 - 0.34 10.7 35.6 0.16 11.8 9.6 3.7 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF883 PF05957.8 KFM01483.1 - 0.42 11.0 18.7 2.4 8.5 4.1 3.9 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) CENP-Q PF13094.1 KFM01483.1 - 0.53 10.2 29.4 0.3 11.0 2.4 2.9 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit HALZ PF02183.13 KFM01483.1 - 0.56 9.9 17.5 0.06 13.0 0.5 4.5 4 0 0 4 4 4 0 Homeobox associated leucine zipper BicD PF09730.4 KFM01483.1 - 0.7 8.1 30.8 0.75 8.0 4.6 2.2 1 1 0 2 2 2 0 Microtubule-associated protein Bicaudal-D FUSC PF04632.7 KFM01483.1 - 1 7.7 7.0 0.69 8.2 3.7 1.4 2 0 0 2 2 2 0 Fusaric acid resistance protein family CHDCT2 PF08074.6 KFM01483.1 - 1.1 8.9 8.1 0.83 9.3 0.1 2.6 2 1 1 3 3 3 0 CHDCT2 (NUC038) domain WEMBL PF05701.6 KFM01483.1 - 1.6 7.0 27.6 11 4.3 19.2 2.0 1 1 0 1 1 1 0 Weak chloroplast movement under blue light HOOK PF05622.7 KFM01483.1 - 3.4 5.3 34.7 2.5 5.8 13.5 2.1 1 1 1 2 2 2 0 HOOK protein MitMem_reg PF13012.1 KFM01483.1 - 3.6 7.6 9.5 0.64 10.1 0.2 2.9 3 1 0 3 3 3 0 Maintenance of mitochondrial structure and function DUF4337 PF14235.1 KFM01483.1 - 4 7.2 12.0 1.8 8.4 4.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) DUF972 PF06156.8 KFM01483.1 - 4.8 7.5 34.7 4.8 7.5 1.2 5.1 1 1 2 5 5 5 0 Protein of unknown function (DUF972) Spc7 PF08317.6 KFM01483.1 - 5.6 5.5 32.7 0.05 12.2 6.7 3.2 1 1 1 3 3 3 0 Spc7 kinetochore protein DUF342 PF03961.8 KFM01483.1 - 8.3 4.6 27.3 0.94 7.8 3.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF342) Filament PF00038.16 KFM01484.1 - 1.3e-86 290.9 43.0 1.5e-86 290.7 29.8 1.0 1 0 0 1 1 1 1 Intermediate filament protein CENP-F_leu_zip PF10473.4 KFM01484.1 - 0.0028 17.5 36.3 0.15 11.8 9.0 3.3 1 1 1 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Uds1 PF15456.1 KFM01484.1 - 0.012 15.5 2.6 0.012 15.5 1.8 3.2 2 1 1 3 3 3 0 Up-regulated During Septation HsbA PF12296.3 KFM01484.1 - 0.015 15.1 5.0 1.7 8.5 0.9 2.5 2 1 0 2 2 2 0 Hydrophobic surface binding protein A LURAP PF14854.1 KFM01484.1 - 0.04 13.6 1.1 8.2 6.1 0.0 3.0 2 0 0 2 2 2 0 Leucine rich adaptor protein Myosin_tail_1 PF01576.14 KFM01484.1 - 1.5 6.4 38.8 0.028 12.1 5.6 2.7 1 1 0 2 2 2 0 Myosin tail Tropomyosin_1 PF12718.2 KFM01484.1 - 1.6 8.5 33.5 0.033 14.0 6.9 3.0 2 1 1 3 3 3 0 Tropomyosin like IncA PF04156.9 KFM01484.1 - 1.7 8.2 48.0 1.1 8.7 12.2 3.5 1 1 1 3 3 3 0 IncA protein ADIP PF11559.3 KFM01484.1 - 2 8.3 30.2 0.58 10.0 7.2 3.1 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding WXG100 PF06013.7 KFM01484.1 - 2.5 8.1 18.8 1.1 9.3 0.2 4.0 3 1 1 4 4 4 0 Proteins of 100 residues with WXG DUF972 PF06156.8 KFM01484.1 - 3.5 8.0 32.7 0.51 10.7 0.3 4.9 1 1 4 5 5 5 0 Protein of unknown function (DUF972) FlaC_arch PF05377.6 KFM01484.1 - 3.9 7.4 14.6 14 5.6 0.5 5.3 4 2 0 5 5 5 0 Flagella accessory protein C (FlaC) AAA_13 PF13166.1 KFM01484.1 - 4.4 5.6 26.5 0.22 9.9 13.5 2.0 1 1 0 1 1 1 0 AAA domain Rootletin PF15035.1 KFM01484.1 - 4.9 7.0 39.4 32 4.4 5.3 3.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion LMBR1 PF04791.11 KFM01484.1 - 9.3 4.7 14.2 0.6 8.6 4.3 2.0 1 1 1 2 2 2 0 LMBR1-like membrane protein Filament PF00038.16 KFM01485.1 - 7.4e-84 281.8 30.0 8.4e-84 281.6 20.8 1.0 1 0 0 1 1 1 1 Intermediate filament protein FlaC_arch PF05377.6 KFM01485.1 - 0.1 12.4 2.1 0.31 10.9 0.2 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) TPR_MLP1_2 PF07926.7 KFM01485.1 - 0.15 11.8 22.0 0.038 13.7 1.3 3.5 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.7 KFM01485.1 - 0.19 11.5 0.7 0.69 9.7 0.2 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2205 PF10224.4 KFM01485.1 - 0.26 10.8 6.9 6.4 6.4 0.0 3.7 3 0 0 3 3 3 0 Predicted coiled-coil protein (DUF2205) HR1 PF02185.11 KFM01485.1 - 0.56 9.9 4.4 17 5.2 0.2 2.9 2 0 0 2 2 2 0 Hr1 repeat DUF4407 PF14362.1 KFM01485.1 - 0.59 9.0 3.5 1 8.2 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AKNA PF12443.3 KFM01485.1 - 1.5 8.8 9.3 0.19 11.7 1.9 2.6 1 1 1 2 2 2 0 AT-hook-containing transcription factor Filament PF00038.16 KFM01486.1 - 4e-88 295.9 27.1 4.5e-88 295.7 18.8 1.0 1 0 0 1 1 1 1 Intermediate filament protein CENP-F_leu_zip PF10473.4 KFM01486.1 - 0.00077 19.3 6.0 0.00077 19.3 4.2 3.1 1 1 2 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FliJ PF02050.11 KFM01486.1 - 0.026 14.5 3.5 0.026 14.5 2.4 3.5 4 0 0 4 4 4 0 Flagellar FliJ protein Reo_sigmaC PF04582.7 KFM01486.1 - 0.11 11.7 1.0 0.69 9.0 0.1 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein ATG16 PF08614.6 KFM01486.1 - 0.11 12.3 17.2 0.07 12.9 4.6 2.9 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) IncA PF04156.9 KFM01486.1 - 2.5 7.6 29.1 0.032 13.8 5.2 3.0 2 1 1 3 3 3 0 IncA protein TPR_MLP1_2 PF07926.7 KFM01486.1 - 9.4 5.9 22.6 0.48 10.1 0.5 3.4 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein IATP PF04568.7 KFM01486.1 - 9.4 6.3 10.2 15 5.7 0.2 3.9 3 1 1 4 4 4 0 Mitochondrial ATPase inhibitor, IATP DUF1664 PF07889.7 KFM01486.1 - 9.9 5.9 7.9 5.6 6.7 0.2 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Filament PF00038.16 KFM01487.1 - 2.4e-108 362.3 32.2 2.8e-108 362.1 22.3 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 KFM01487.1 - 0.00078 19.1 2.4 0.00078 19.1 1.7 3.6 3 1 0 3 3 3 1 TPR/MLP1/MLP2-like protein IncA PF04156.9 KFM01487.1 - 0.0011 18.6 25.5 0.031 13.8 5.0 3.5 2 1 0 2 2 2 1 IncA protein ATG16 PF08614.6 KFM01487.1 - 0.0053 16.6 24.8 0.026 14.3 6.2 3.0 1 1 2 3 3 3 2 Autophagy protein 16 (ATG16) COG5 PF10392.4 KFM01487.1 - 0.006 16.5 1.8 0.022 14.7 1.3 2.0 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Baculo_PEP_C PF04513.7 KFM01487.1 - 0.049 13.4 0.4 0.049 13.4 0.3 3.9 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-F_leu_zip PF10473.4 KFM01487.1 - 0.16 11.8 22.1 0.35 10.7 2.9 3.4 2 2 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_1 PF00170.16 KFM01487.1 - 0.17 11.8 13.3 0.44 10.5 0.3 4.8 4 1 0 4 4 4 0 bZIP transcription factor Tropomyosin_1 PF12718.2 KFM01487.1 - 0.19 11.5 27.3 0.082 12.7 5.5 2.8 2 1 1 3 3 3 0 Tropomyosin like DUF2935 PF11155.3 KFM01487.1 - 0.44 10.6 0.1 0.44 10.6 0.0 3.5 2 2 1 3 3 3 0 Domain of unknown function (DUF2935) DUF3618 PF12277.3 KFM01487.1 - 0.5 10.4 4.6 4.2 7.4 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) ADIP PF11559.3 KFM01487.1 - 0.55 10.1 23.4 0.18 11.6 2.1 3.8 1 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding Myosin_tail_1 PF01576.14 KFM01487.1 - 0.82 7.3 33.1 0.012 13.3 3.7 2.7 1 1 0 3 3 3 0 Myosin tail Reo_sigmaC PF04582.7 KFM01487.1 - 0.89 8.6 4.5 5.1 6.1 0.6 2.5 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Fib_alpha PF08702.5 KFM01487.1 - 4.7 7.3 17.8 0.53 10.4 0.6 3.6 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Tup_N PF08581.5 KFM01487.1 - 4.8 7.4 18.0 5.9 7.1 0.7 5.1 4 2 1 5 5 5 0 Tup N-terminal DUF342 PF03961.8 KFM01487.1 - 5.6 5.2 19.7 1.8 6.8 4.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF883 PF05957.8 KFM01487.1 - 5.8 7.3 14.3 15 6.0 2.2 4.5 3 1 0 4 4 4 0 Bacterial protein of unknown function (DUF883) Filament PF00038.16 KFM01488.1 - 8.8e-112 373.6 35.9 1e-111 373.3 24.9 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 KFM01488.1 - 0.00017 21.3 32.6 0.00026 20.7 0.8 3.8 3 1 1 4 4 4 2 TPR/MLP1/MLP2-like protein Myosin_tail_1 PF01576.14 KFM01488.1 - 0.0015 16.3 4.6 0.0015 16.3 3.2 2.6 1 1 0 2 2 2 2 Myosin tail CENP-F_leu_zip PF10473.4 KFM01488.1 - 0.002 18.0 27.2 0.025 14.4 5.8 3.6 1 1 1 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.7 KFM01488.1 - 0.011 15.5 1.2 0.011 15.5 0.9 4.4 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus bZIP_1 PF00170.16 KFM01488.1 - 0.024 14.6 0.1 0.024 14.6 0.0 5.0 5 1 0 5 5 5 0 bZIP transcription factor Reo_sigmaC PF04582.7 KFM01488.1 - 0.028 13.6 6.2 0.3 10.2 0.6 2.4 2 1 0 2 2 2 0 Reovirus sigma C capsid protein DED PF01335.16 KFM01488.1 - 0.034 14.2 2.8 0.83 9.8 0.0 2.6 2 0 0 2 2 2 0 Death effector domain ADIP PF11559.3 KFM01488.1 - 0.038 13.8 26.5 0.19 11.6 1.9 3.7 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding ACCA PF03255.9 KFM01488.1 - 0.07 12.6 13.7 0.51 9.8 0.5 3.4 2 1 1 4 4 4 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit AAA_13 PF13166.1 KFM01488.1 - 0.086 11.2 23.3 0.014 13.8 12.9 2.0 1 1 0 1 1 1 0 AAA domain Hemerythrin PF01814.18 KFM01488.1 - 0.13 12.4 6.6 2 8.6 0.1 2.8 2 1 0 2 2 2 0 Hemerythrin HHE cation binding domain Fib_alpha PF08702.5 KFM01488.1 - 0.15 12.1 19.7 0.11 12.5 0.5 3.6 1 1 1 4 4 4 0 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.2 KFM01488.1 - 0.17 11.7 29.9 0.36 10.6 8.2 3.5 2 1 2 4 4 4 0 Tropomyosin like IncA PF04156.9 KFM01488.1 - 0.2 11.2 32.0 0.19 11.2 8.1 3.3 1 1 3 4 4 4 0 IncA protein DUF883 PF05957.8 KFM01488.1 - 0.33 11.3 20.4 0.5 10.7 4.1 4.8 3 1 2 5 5 5 0 Bacterial protein of unknown function (DUF883) DUF948 PF06103.6 KFM01488.1 - 0.68 9.8 9.8 3.9 7.3 0.7 4.3 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF2580 PF10824.3 KFM01488.1 - 0.73 10.2 4.3 1.2 9.4 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2580) Spc7 PF08317.6 KFM01488.1 - 1.1 7.8 29.8 0.059 12.0 7.3 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein COMP PF11598.3 KFM01488.1 - 3.4 7.8 5.3 73 3.5 0.1 4.0 4 0 0 4 4 4 0 Cartilage oligomeric matrix protein DUF1664 PF07889.7 KFM01488.1 - 7.2 6.4 14.6 5.2 6.8 0.3 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.6 KFM01488.1 - 8.8 6.3 13.6 4.3 7.2 0.5 5.0 5 1 0 5 5 5 0 Flagella accessory protein C (FlaC) ApoLp-III PF07464.6 KFM01488.1 - 9.7 6.1 16.3 0.093 12.7 3.8 2.7 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Filament PF00038.16 KFM01489.1 - 1.5e-110 369.5 37.7 1.7e-110 369.3 26.1 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 KFM01489.1 - 9.2e-05 22.1 33.8 0.013 15.2 9.6 3.7 2 2 0 3 3 3 2 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 KFM01489.1 - 0.0003 20.0 4.2 0.0075 15.4 0.1 2.5 2 0 0 2 2 2 1 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 KFM01489.1 - 0.00033 20.5 28.4 0.001 18.9 5.6 3.5 1 1 2 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Phage_GP20 PF06810.6 KFM01489.1 - 0.0016 17.9 6.2 0.0016 17.9 4.3 3.5 2 1 0 3 3 3 1 Phage minor structural protein GP20 Tropomyosin_1 PF12718.2 KFM01489.1 - 0.0018 18.1 12.4 0.0018 18.1 8.6 3.5 2 1 0 3 3 3 1 Tropomyosin like MscS_porin PF12795.2 KFM01489.1 - 0.0032 16.8 11.7 0.0032 16.8 8.1 3.0 1 1 2 3 3 3 1 Mechanosensitive ion channel porin domain Myosin_tail_1 PF01576.14 KFM01489.1 - 0.0049 14.6 36.3 0.0063 14.3 2.9 2.9 1 1 2 3 3 3 2 Myosin tail Baculo_PEP_C PF04513.7 KFM01489.1 - 0.0071 16.1 19.8 0.28 11.0 0.4 4.1 2 1 2 4 4 4 3 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4254 PF14063.1 KFM01489.1 - 0.014 14.9 0.3 0.014 14.9 0.2 4.4 3 1 1 5 5 5 0 Protein of unknown function (DUF4254) SlyX PF04102.7 KFM01489.1 - 0.12 12.8 0.4 0.12 12.8 0.3 4.1 3 2 1 4 4 4 0 SlyX ADIP PF11559.3 KFM01489.1 - 0.2 11.5 30.0 0.087 12.7 7.2 4.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding YdjC PF04794.7 KFM01489.1 - 0.22 10.9 3.1 1.1 8.6 0.1 2.6 2 1 1 3 3 3 0 YdjC-like protein WEMBL PF05701.6 KFM01489.1 - 0.3 9.4 28.8 0.44 8.9 20.0 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light AAA_13 PF13166.1 KFM01489.1 - 0.34 9.3 27.4 0.041 12.3 14.8 2.2 1 1 0 1 1 1 0 AAA domain TMF_DNA_bd PF12329.3 KFM01489.1 - 0.65 9.8 26.9 0.075 12.8 0.7 4.6 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding FlaC_arch PF05377.6 KFM01489.1 - 0.73 9.7 17.2 0.28 11.0 0.1 5.1 5 1 0 5 5 5 0 Flagella accessory protein C (FlaC) Mnd1 PF03962.10 KFM01489.1 - 2.2 7.9 28.5 0.13 11.9 5.2 4.0 1 1 3 4 4 4 0 Mnd1 family IncA PF04156.9 KFM01489.1 - 2.3 7.7 36.3 0.1 12.1 9.4 3.8 1 1 3 4 4 4 0 IncA protein Fib_alpha PF08702.5 KFM01489.1 - 2.8 8.0 23.1 0.6 10.2 2.1 3.8 1 1 4 5 5 5 0 Fibrinogen alpha/beta chain family DUF883 PF05957.8 KFM01489.1 - 2.9 8.3 18.7 2.1 8.7 4.7 4.2 2 1 2 5 5 5 0 Bacterial protein of unknown function (DUF883) DUF4140 PF13600.1 KFM01489.1 - 3 8.3 23.3 5.3 7.5 2.7 4.8 2 1 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) Transposase_22 PF02994.9 KFM01489.1 - 4.4 5.6 19.9 0.19 10.1 3.4 2.6 1 1 1 2 2 2 0 L1 transposable element NPV_P10 PF05531.7 KFM01489.1 - 4.8 7.4 14.3 8 6.7 1.2 4.3 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.6 KFM01489.1 - 5.4 6.9 12.1 0.99 9.3 0.5 4.3 2 2 3 5 5 5 0 Bacterial protein of unknown function (DUF948) Atg14 PF10186.4 KFM01489.1 - 6.1 5.6 24.7 2.1 7.2 8.2 2.8 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 FUSC PF04632.7 KFM01489.1 - 6.4 5.0 4.7 8.9 4.6 3.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Filament PF00038.16 KFM01490.1 - 4.1e-109 364.8 35.2 4.7e-109 364.6 24.4 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 KFM01490.1 - 1.8e-05 24.4 31.7 0.00069 19.3 2.8 3.7 2 2 1 3 3 3 2 TPR/MLP1/MLP2-like protein ADIP PF11559.3 KFM01490.1 - 0.00011 22.1 29.1 0.035 13.9 6.5 4.1 2 2 1 3 3 3 2 Afadin- and alpha -actinin-Binding AAA_13 PF13166.1 KFM01490.1 - 0.00016 20.3 16.6 0.00016 20.3 11.5 2.2 1 1 1 2 2 2 1 AAA domain CENP-F_leu_zip PF10473.4 KFM01490.1 - 0.00026 20.8 6.2 0.00026 20.8 4.3 3.4 1 1 2 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Phage_GP20 PF06810.6 KFM01490.1 - 0.00037 19.9 3.7 0.00037 19.9 2.5 3.9 2 1 1 3 3 3 1 Phage minor structural protein GP20 Tropomyosin_1 PF12718.2 KFM01490.1 - 0.001 18.9 9.6 0.001 18.9 6.7 3.5 2 1 1 3 3 3 1 Tropomyosin like Reo_sigmaC PF04582.7 KFM01490.1 - 0.0049 16.0 8.1 0.04 13.1 0.5 2.7 1 1 0 2 2 2 1 Reovirus sigma C capsid protein Myosin_tail_1 PF01576.14 KFM01490.1 - 0.042 11.5 34.5 0.016 12.9 20.1 2.3 1 1 1 2 2 2 0 Myosin tail SlyX PF04102.7 KFM01490.1 - 0.045 14.1 0.7 0.045 14.1 0.5 4.4 4 2 1 5 5 5 0 SlyX FlaC_arch PF05377.6 KFM01490.1 - 0.05 13.5 14.6 0.46 10.4 0.1 5.5 4 2 1 6 6 6 0 Flagella accessory protein C (FlaC) Spc7 PF08317.6 KFM01490.1 - 0.06 12.0 31.4 0.09 11.4 6.3 3.3 1 1 2 3 3 3 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.7 KFM01490.1 - 0.18 11.6 22.3 0.16 11.8 1.4 3.6 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.1 KFM01490.1 - 0.19 10.8 32.3 0.028 13.6 6.0 3.4 1 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 KFM01490.1 - 0.25 10.8 36.3 14 5.2 4.3 4.3 1 1 2 3 3 3 0 IncA protein WEMBL PF05701.6 KFM01490.1 - 0.27 9.6 27.6 0.47 8.8 19.2 1.4 1 0 0 1 1 1 0 Weak chloroplast movement under blue light DUF948 PF06103.6 KFM01490.1 - 0.33 10.8 11.8 1.2 8.9 0.6 4.1 2 2 3 5 5 5 0 Bacterial protein of unknown function (DUF948) Mnd1 PF03962.10 KFM01490.1 - 0.42 10.2 27.1 0.031 13.9 5.0 3.7 1 1 3 4 4 4 0 Mnd1 family ApoLp-III PF07464.6 KFM01490.1 - 1.2 9.1 19.9 0.019 15.0 4.6 3.4 1 1 2 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Fib_alpha PF08702.5 KFM01490.1 - 1.6 8.8 21.5 0.5 10.4 3.1 3.5 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF3450 PF11932.3 KFM01490.1 - 2.1 7.5 27.6 0.093 11.9 2.9 4.0 1 1 1 4 4 4 0 Protein of unknown function (DUF3450) DUF883 PF05957.8 KFM01490.1 - 2.5 8.5 19.1 8.6 6.8 4.7 4.5 2 1 2 5 5 5 0 Bacterial protein of unknown function (DUF883) DUF3571 PF12095.3 KFM01490.1 - 2.8 8.2 9.9 0.57 10.4 0.4 3.6 2 2 2 4 4 3 0 Protein of unknown function (DUF3571) Rootletin PF15035.1 KFM01490.1 - 3.5 7.5 29.2 4.4 7.2 9.0 2.5 1 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion GA PF01468.12 KFM01490.1 - 4.3 7.5 7.3 1.9 8.7 0.5 2.8 2 0 0 2 2 2 0 GA module TMF_DNA_bd PF12329.3 KFM01490.1 - 4.6 7.1 31.3 0.063 13.0 2.2 4.9 4 1 1 5 5 5 0 TATA element modulatory factor 1 DNA binding BRE1 PF08647.6 KFM01490.1 - 6 6.9 23.8 0.25 11.3 2.2 4.1 1 1 2 4 4 4 0 BRE1 E3 ubiquitin ligase DUF4140 PF13600.1 KFM01490.1 - 6.3 7.2 22.5 0.3 11.5 1.2 4.7 3 1 1 5 5 5 0 N-terminal domain of unknown function (DUF4140) Kinesin-relat_1 PF12711.2 KFM01490.1 - 6.4 7.2 16.7 1.3 9.4 0.7 4.2 2 2 1 4 4 4 0 Kinesin motor Atg14 PF10186.4 KFM01490.1 - 6.7 5.5 23.9 7.1 5.4 3.1 2.7 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 KFM01490.1 - 7 4.3 22.3 2.7 5.7 9.8 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Filament PF00038.16 KFM01491.1 - 1.6e-109 366.1 32.3 1.9e-109 365.9 22.4 1.0 1 0 0 1 1 1 1 Intermediate filament protein ADIP PF11559.3 KFM01491.1 - 0.0029 17.5 3.7 0.0029 17.5 2.6 4.0 2 1 2 4 4 4 1 Afadin- and alpha -actinin-Binding Phage_GP20 PF06810.6 KFM01491.1 - 0.0075 15.7 5.4 0.0075 15.7 3.7 3.9 1 1 4 5 5 5 1 Phage minor structural protein GP20 Baculo_PEP_C PF04513.7 KFM01491.1 - 0.011 15.6 16.8 0.028 14.2 0.5 3.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-F_leu_zip PF10473.4 KFM01491.1 - 0.015 15.1 4.9 0.015 15.1 3.4 4.0 1 1 3 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 KFM01491.1 - 0.015 15.0 28.4 0.11 12.2 0.9 3.8 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein ApoLp-III PF07464.6 KFM01491.1 - 0.018 15.1 5.1 0.018 15.1 3.5 2.6 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) DivIC PF04977.10 KFM01491.1 - 0.036 13.5 0.3 0.036 13.5 0.2 5.1 3 2 3 6 6 6 0 Septum formation initiator CCDC92 PF14916.1 KFM01491.1 - 0.051 13.1 0.0 0.051 13.1 0.0 3.2 3 1 1 4 4 4 0 Coiled-coil domain of unknown function Myosin_tail_1 PF01576.14 KFM01491.1 - 0.096 10.3 33.0 0.83 7.2 8.0 2.9 1 1 0 2 2 2 0 Myosin tail IncA PF04156.9 KFM01491.1 - 0.15 11.6 27.6 0.27 10.8 5.7 3.4 1 1 3 4 4 4 0 IncA protein AAA_13 PF13166.1 KFM01491.1 - 0.33 9.3 23.5 0.033 12.6 11.9 2.1 1 1 0 1 1 1 0 AAA domain Atg14 PF10186.4 KFM01491.1 - 0.54 9.1 17.8 0.79 8.6 0.8 2.3 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 ACCA PF03255.9 KFM01491.1 - 0.63 9.5 11.9 1.6 8.2 0.4 3.5 2 1 1 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF883 PF05957.8 KFM01491.1 - 0.97 9.8 17.1 1.7 9.1 3.7 4.3 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF883) Fib_alpha PF08702.5 KFM01491.1 - 1.9 8.6 18.0 0.63 10.1 0.6 3.5 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.6 KFM01491.1 - 2.4 8.1 9.3 6.7 6.7 0.1 5.1 6 0 0 6 6 6 0 Flagella accessory protein C (FlaC) DUF4164 PF13747.1 KFM01491.1 - 5.9 7.1 21.3 0.74 9.9 0.6 4.1 2 2 1 4 4 4 0 Domain of unknown function (DUF4164) APG6 PF04111.7 KFM01491.1 - 6.2 5.7 26.4 0.097 11.6 3.0 3.2 1 1 1 3 3 3 0 Autophagy protein Apg6 bZIP_1 PF00170.16 KFM01491.1 - 7.2 6.6 15.5 16 5.5 0.0 5.1 5 1 0 5 5 5 0 bZIP transcription factor Ax_dynein_light PF10211.4 KFM01491.1 - 7.3 6.3 22.9 0.43 10.3 2.9 4.3 1 1 3 5 5 5 0 Axonemal dynein light chain Filament PF00038.16 KFM01492.1 - 1.2e-109 366.6 38.9 1.4e-109 366.4 27.0 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 KFM01492.1 - 0.00019 21.1 34.8 0.00019 21.1 0.5 4.1 3 1 0 3 3 3 1 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.5 KFM01492.1 - 0.0032 17.6 21.9 0.076 13.1 0.4 3.9 3 1 1 4 4 4 2 Fibrinogen alpha/beta chain family Myosin_tail_1 PF01576.14 KFM01492.1 - 0.0081 13.9 42.8 0.0038 15.0 25.0 2.5 1 1 1 2 2 2 1 Myosin tail CENP-F_leu_zip PF10473.4 KFM01492.1 - 0.015 15.1 33.7 0.13 12.1 7.4 4.0 1 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.3 KFM01492.1 - 0.052 13.4 29.5 0.31 10.9 2.8 4.5 2 2 2 4 4 4 0 Afadin- and alpha -actinin-Binding DUF4633 PF15464.1 KFM01492.1 - 0.082 12.7 1.2 0.22 11.3 0.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4633) 23S_rRNA_IVP PF05635.6 KFM01492.1 - 0.11 12.4 7.2 1.5 8.7 0.6 2.8 2 1 0 2 2 2 0 23S rRNA-intervening sequence protein Reo_sigmaC PF04582.7 KFM01492.1 - 0.28 10.3 5.4 5.3 6.1 1.4 2.9 1 1 2 3 3 3 0 Reovirus sigma C capsid protein DUF948 PF06103.6 KFM01492.1 - 0.66 9.8 13.3 8.3 6.3 0.1 4.9 3 1 2 5 5 5 0 Bacterial protein of unknown function (DUF948) AAA_13 PF13166.1 KFM01492.1 - 0.79 8.1 32.3 1 7.7 18.3 2.6 1 1 1 2 2 2 0 AAA domain Seryl_tRNA_N PF02403.17 KFM01492.1 - 1.6 8.7 36.3 0.039 13.9 8.4 3.9 1 1 3 4 4 4 0 Seryl-tRNA synthetase N-terminal domain DUF4140 PF13600.1 KFM01492.1 - 1.6 9.1 25.4 8.1 6.9 0.0 5.5 2 1 3 5 5 5 0 N-terminal domain of unknown function (DUF4140) DASH_Duo1 PF08651.5 KFM01492.1 - 2.1 7.9 9.1 0.84 9.2 0.6 3.7 3 1 1 4 4 4 0 DASH complex subunit Duo1 AAA_27 PF13514.1 KFM01492.1 - 3.4 5.2 32.5 11 3.5 22.5 1.8 1 1 0 1 1 1 0 AAA domain Tropomyosin_1 PF12718.2 KFM01492.1 - 4.1 7.2 40.4 0.053 13.3 3.4 4.6 1 1 4 5 5 5 0 Tropomyosin like Atg14 PF10186.4 KFM01492.1 - 4.2 6.2 23.4 1.4 7.7 0.5 2.4 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Filament PF00038.16 KFM01494.1 - 7.6e-74 248.9 32.0 8.7e-74 248.7 22.2 1.0 1 0 0 1 1 1 1 Intermediate filament protein IncA PF04156.9 KFM01494.1 - 0.00031 20.3 28.2 0.0056 16.3 5.2 2.5 1 1 1 2 2 2 2 IncA protein CorA PF01544.13 KFM01494.1 - 0.005 15.9 1.2 0.005 15.9 0.8 2.7 2 1 2 4 4 4 1 CorA-like Mg2+ transporter protein Seryl_tRNA_N PF02403.17 KFM01494.1 - 0.011 15.7 2.6 0.011 15.7 1.8 3.5 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Reo_sigmaC PF04582.7 KFM01494.1 - 0.14 11.2 5.6 4.3 6.4 0.7 2.9 1 1 3 4 4 4 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 KFM01494.1 - 0.14 11.9 7.4 0.37 10.6 0.5 3.6 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DegS PF05384.6 KFM01494.1 - 0.22 10.7 17.5 0.014 14.6 3.1 3.7 1 1 0 2 2 2 0 Sensor protein DegS DivIC PF04977.10 KFM01494.1 - 1.2 8.6 19.6 4 7.0 0.4 4.9 3 1 1 4 4 4 0 Septum formation initiator DUF3887 PF13026.1 KFM01494.1 - 8.9 6.6 12.7 0.12 12.6 1.6 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3887) Bin3 PF06859.7 KFM01495.1 - 4.9e-12 45.8 0.0 6.6e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_12 PF08242.7 KFM01495.1 - 3.4e-06 27.4 0.0 0.00024 21.5 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFM01495.1 - 8.3e-06 25.4 0.0 1.3e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFM01495.1 - 0.00053 20.5 0.0 0.0028 18.2 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFM01495.1 - 0.0086 16.1 0.0 0.023 14.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFM01495.1 - 0.033 14.5 0.2 0.21 11.9 0.0 2.1 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 KFM01495.1 - 0.053 14.0 0.1 2 8.9 0.1 3.1 1 1 0 1 1 1 0 Methyltransferase domain HHH_8 PF14716.1 KFM01495.1 - 0.1 12.7 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix domain Bax1-I PF01027.15 KFM01496.1 - 2.5e-13 50.1 14.2 3e-13 49.8 9.8 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 NrfD_2 PF14589.1 KFM01496.1 - 0.019 14.6 0.9 0.024 14.3 0.6 1.2 1 0 0 1 1 1 0 Polysulfide reductase MIP PF00230.15 KFM01497.1 - 4.2e-81 271.7 9.5 4.9e-81 271.5 6.6 1.0 1 0 0 1 1 1 1 Major intrinsic protein MIP PF00230.15 KFM01498.1 - 7.5e-74 248.0 14.6 8.8e-74 247.7 10.1 1.0 1 0 0 1 1 1 1 Major intrinsic protein Ephrin PF00812.12 KFM01499.1 - 1.2e-56 190.3 0.2 1.5e-55 186.6 0.0 2.0 2 0 0 2 2 2 1 Ephrin Shisa PF13908.1 KFM01499.1 - 0.00011 22.3 0.0 0.0002 21.5 0.0 1.5 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator Rifin_STEVOR PF02009.11 KFM01499.1 - 0.0035 17.0 0.0 0.0043 16.7 0.0 1.2 1 0 0 1 1 1 1 Rifin/stevor family Profilin PF00235.14 KFM01499.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Profilin Podoplanin PF05808.6 KFM01499.1 - 0.013 15.0 0.4 0.02 14.4 0.1 1.4 1 1 0 1 1 1 0 Podoplanin EphA2_TM PF14575.1 KFM01499.1 - 0.053 13.9 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain UPF0560 PF10577.4 KFM01499.1 - 0.13 10.4 0.0 0.19 9.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TMEM154 PF15102.1 KFM01499.1 - 0.17 11.5 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family ARGLU PF15346.1 KFM01500.1 - 7e-49 165.4 59.4 7e-49 165.4 41.2 2.0 2 0 0 2 2 2 1 Arginine and glutamate-rich 1 Asp-B-Hydro_N PF05279.6 KFM01500.1 - 3.6 7.3 39.3 0.067 13.0 19.5 2.0 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region Histone PF00125.19 KFM01502.1 - 4.9e-26 90.6 0.1 6.8e-26 90.1 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFM01502.1 - 9.5e-07 28.7 0.5 2.3e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KFM01502.1 - 0.0026 18.0 0.0 0.0049 17.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF2606 PF10794.4 KFM01502.1 - 0.038 13.4 0.2 0.061 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) Lipase PF00151.14 KFM01503.1 - 3.8e-107 358.3 0.0 4.6e-107 358.0 0.0 1.1 1 0 0 1 1 1 1 Lipase PLAT PF01477.18 KFM01503.1 - 1.3e-21 77.1 0.7 2.1e-21 76.3 0.5 1.4 1 0 0 1 1 1 1 PLAT/LH2 domain Abhydrolase_6 PF12697.2 KFM01503.1 - 1e-07 32.0 0.1 1.3e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFM01503.1 - 0.00047 19.9 0.0 0.00076 19.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Sec7 PF01369.15 KFM01504.1 - 3e-50 170.5 0.5 5.8e-50 169.6 0.3 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 KFM01504.1 - 1.1e-40 138.4 1.6 8.2e-40 135.6 0.5 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 KFM01504.1 - 7e-13 48.6 0.2 1.7e-12 47.4 0.2 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KFM01504.1 - 0.034 14.3 0.3 0.094 12.9 0.2 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain PH_4 PF15404.1 KFM01504.1 - 0.063 12.8 2.1 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain NIPSNAP PF07978.8 KFM01506.1 - 1.4e-51 172.6 0.3 2.6e-26 91.5 0.0 2.0 2 0 0 2 2 2 2 NIPSNAP ABC2_membrane_3 PF12698.2 KFM01507.1 - 4.1e-55 187.2 48.1 1.3e-43 149.4 12.5 3.1 3 0 0 3 3 3 2 ABC-2 family transporter protein ABC_tran PF00005.22 KFM01507.1 - 1.3e-52 177.7 0.0 5.2e-29 101.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KFM01507.1 - 2.3e-19 70.4 0.0 3e-08 33.9 0.0 4.6 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KFM01507.1 - 0.00076 18.9 2.0 0.061 12.8 0.3 3.0 3 0 0 3 3 3 1 P-loop containing region of AAA domain DUF4162 PF13732.1 KFM01507.1 - 0.0041 17.6 0.0 0.17 12.3 0.0 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) AAA_23 PF13476.1 KFM01507.1 - 0.0042 17.4 5.0 0.02 15.2 0.2 2.6 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 KFM01507.1 - 0.014 15.2 0.0 6.4 6.7 0.0 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 KFM01507.1 - 0.017 14.2 0.0 2.6 7.0 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain DUF258 PF03193.11 KFM01507.1 - 0.12 11.5 0.3 4.3 6.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Choline_transpo PF04515.7 KFM01508.1 - 8.9e-102 340.2 35.6 8.9e-102 340.2 24.7 2.2 2 0 0 2 2 2 1 Plasma-membrane choline transporter DUF4131 PF13567.1 KFM01508.1 - 0.4 10.0 0.0 0.4 10.0 0.0 4.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) SPRY PF00622.23 KFM01509.1 - 1.4e-16 60.6 0.2 3.1e-16 59.5 0.2 1.5 1 0 0 1 1 1 1 SPRY domain fn3 PF00041.16 KFM01509.1 - 1.4e-06 28.3 0.0 5.9e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 Fibronectin type III domain NPV_P10 PF05531.7 KFM01509.1 - 0.011 15.9 4.3 5.2 7.3 3.0 2.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF3086 PF11285.3 KFM01509.1 - 0.057 12.2 0.6 0.093 11.5 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) V_ATPase_I PF01496.14 KFM01509.1 - 0.11 10.3 3.3 0.14 9.9 2.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mer2 PF09074.5 KFM01509.1 - 0.14 12.1 5.1 0.3 10.9 3.5 1.6 1 0 0 1 1 1 0 Mer2 DUF148 PF02520.12 KFM01509.1 - 0.33 10.7 3.7 0.61 9.8 2.6 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF148 Fib_alpha PF08702.5 KFM01509.1 - 0.82 9.7 4.3 2.4 8.2 3.0 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.6 KFM01509.1 - 1.4 8.9 4.7 0.95 9.4 0.2 2.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) LicD PF04991.8 KFM01510.1 - 2.6e-13 50.5 1.5 2.5e-11 44.1 0.3 3.1 2 1 0 2 2 2 1 LicD family HLH PF00010.21 KFM01511.1 - 5.7e-17 61.1 0.8 7.7e-17 60.7 0.6 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TRIC PF05197.8 KFM01512.1 - 3.6e-91 303.9 4.7 4.3e-91 303.6 3.3 1.1 1 0 0 1 1 1 1 TRIC channel UPF0126 PF03458.8 KFM01512.1 - 0.005 16.4 4.5 0.26 10.9 0.0 2.7 2 1 0 2 2 2 2 UPF0126 domain zf-H2C2_5 PF13909.1 KFM01513.1 - 1.2e-52 173.1 267.2 0.00014 21.8 0.6 32.5 32 0 0 32 32 32 26 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 KFM01513.1 - 0.00029 20.9 0.7 0.0017 18.5 0.1 31.9 33 1 0 33 33 33 17 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFM01513.1 - 0.0027 17.9 6.7 0.0027 17.9 4.7 29.9 34 0 0 34 34 34 12 Zinc-finger double domain zf-C2H2 PF00096.21 KFM01513.1 - 0.012 15.9 0.2 0.012 15.9 0.1 30.5 34 0 0 34 34 34 0 Zinc finger, C2H2 type XPC-binding PF09280.6 KFM01514.1 - 1.6e-25 88.3 18.2 2.6e-25 87.6 12.6 1.4 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.26 KFM01514.1 - 1.6e-22 78.6 0.9 1.1e-12 47.3 0.1 2.7 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.18 KFM01514.1 - 3e-15 55.3 0.1 5.5e-15 54.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family UBA_3 PF09288.5 KFM01514.1 - 0.00035 20.1 0.0 0.0088 15.6 0.0 2.3 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain Rad60-SLD_2 PF13881.1 KFM01514.1 - 0.0016 18.2 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rap1_C PF11626.3 KFM01514.1 - 0.019 14.8 0.0 7.4 6.5 0.0 2.5 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF2407 PF10302.4 KFM01514.1 - 0.025 14.7 0.0 0.046 13.9 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF4502 PF14950.1 KFM01514.1 - 0.25 10.4 2.3 0.3 10.2 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4502) zf-C2H2 PF00096.21 KFM01515.1 - 3.9e-16 58.3 21.3 1.4e-05 25.0 2.1 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM01515.1 - 7.4e-13 47.8 18.5 0.00028 21.0 1.8 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFM01515.1 - 3.3e-12 46.0 25.1 8.2e-07 29.0 2.1 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.2 KFM01515.1 - 0.016 15.4 4.9 0.75 10.0 0.3 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn_Tnp_IS1 PF03811.8 KFM01515.1 - 0.12 11.8 3.2 0.29 10.6 2.2 1.6 1 0 0 1 1 1 0 InsA N-terminal domain zf-C2H2_jaz PF12171.3 KFM01515.1 - 0.19 11.9 5.3 1.5 9.0 0.5 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 KFM01515.1 - 1.1 9.6 7.1 0.61 10.4 0.8 2.3 1 1 1 2 2 2 0 TRAF-type zinc finger zf-BED PF02892.10 KFM01515.1 - 3.3 7.5 12.6 11 5.8 2.2 3.0 2 1 0 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.1 KFM01515.1 - 8.2 6.4 8.9 1.3 9.0 0.5 3.0 2 1 0 2 2 2 0 C2H2-type zinc finger RVT_1 PF00078.22 KFM01516.1 - 0.062 12.6 0.0 0.091 12.0 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2_2 PF13465.1 KFM01517.1 - 1.4e-16 59.8 11.8 1.1e-11 44.4 0.6 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFM01517.1 - 1.1e-15 56.8 8.5 7.3e-08 32.3 0.5 2.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KFM01517.1 - 3.2e-11 42.7 6.6 3.1e-06 26.8 0.2 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KFM01517.1 - 5.5e-10 38.8 6.7 2.4e-05 24.3 0.2 2.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM01517.1 - 4.2e-05 23.5 1.1 0.0083 16.2 0.0 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 KFM01517.1 - 5.3e-05 23.0 1.2 0.00064 19.6 0.8 2.1 1 1 0 1 1 1 1 Zinc ribbon domain UPF0547 PF10571.4 KFM01517.1 - 0.0022 17.6 4.0 0.14 11.8 0.5 2.1 2 0 0 2 2 2 1 Uncharacterised protein family UPF0547 Prok-RING_1 PF14446.1 KFM01517.1 - 0.0024 17.5 0.3 0.18 11.5 0.0 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 C1_4 PF07975.7 KFM01517.1 - 0.0026 17.7 0.0 0.015 15.2 0.0 1.8 1 1 0 1 1 1 1 TFIIH C1-like domain zf-ribbon_3 PF13248.1 KFM01517.1 - 0.0033 16.5 2.6 0.14 11.3 0.2 2.2 2 0 0 2 2 2 1 zinc-ribbon domain XPA_N PF01286.13 KFM01517.1 - 0.004 16.8 2.0 0.98 9.1 0.2 2.2 2 0 0 2 2 2 2 XPA protein N-terminal DZR PF12773.2 KFM01517.1 - 0.0054 16.5 0.8 0.0081 15.9 0.6 1.3 1 0 0 1 1 1 1 Double zinc ribbon TF_Zn_Ribbon PF08271.7 KFM01517.1 - 0.0066 15.7 0.5 0.11 11.8 0.0 2.1 2 0 0 2 2 2 1 TFIIB zinc-binding YhfH PF14149.1 KFM01517.1 - 0.0072 16.0 1.0 1.1 9.0 0.2 2.2 2 0 0 2 2 2 1 YhfH-like protein CpXC PF14353.1 KFM01517.1 - 0.009 15.9 0.1 0.22 11.4 0.1 2.0 1 1 0 1 1 1 1 CpXC protein zinc_ribbon_2 PF13240.1 KFM01517.1 - 0.0094 15.4 5.0 0.9 9.1 1.1 2.1 1 1 0 2 2 2 1 zinc-ribbon domain Zn_ribbon_recom PF13408.1 KFM01517.1 - 0.01 16.0 0.8 2.5 8.4 0.1 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain zinc_ribbon_5 PF13719.1 KFM01517.1 - 0.013 15.0 0.9 0.52 9.9 0.7 2.1 1 1 1 2 2 2 0 zinc-ribbon domain zf-ISL3 PF14690.1 KFM01517.1 - 0.013 15.5 2.6 0.55 10.3 0.1 2.3 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zinc_ribbon_4 PF13717.1 KFM01517.1 - 0.016 14.9 0.8 0.58 9.8 0.6 2.1 1 1 1 2 2 2 0 zinc-ribbon domain DUF1610 PF07754.6 KFM01517.1 - 0.016 15.2 5.4 0.018 15.1 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) zf-met PF12874.2 KFM01517.1 - 0.022 14.9 3.8 1.2 9.3 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-Di19 PF05605.7 KFM01517.1 - 0.025 14.7 0.4 0.088 12.9 0.2 1.8 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding C1_1 PF00130.17 KFM01517.1 - 0.039 13.6 0.2 0.21 11.3 0.1 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DNA_RNApol_7kD PF03604.8 KFM01517.1 - 0.042 13.3 2.2 3 7.3 0.1 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit LIM PF00412.17 KFM01517.1 - 0.042 13.9 0.3 0.12 12.4 0.2 1.7 1 1 0 1 1 1 0 LIM domain FYDLN_acid PF09538.5 KFM01517.1 - 0.055 14.0 0.8 0.58 10.7 0.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) FYVE PF01363.16 KFM01517.1 - 0.063 13.1 2.1 1.7 8.6 0.1 2.0 1 1 1 2 2 2 0 FYVE zinc finger HypA PF01155.14 KFM01517.1 - 0.067 12.8 0.7 0.078 12.6 0.5 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-RING_3 PF14369.1 KFM01517.1 - 0.07 13.1 2.6 0.25 11.3 0.1 2.1 2 0 0 2 2 2 0 zinc-finger DUF329 PF03884.9 KFM01517.1 - 0.075 12.6 0.5 1.4 8.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF329) TFIIS_C PF01096.13 KFM01517.1 - 0.091 12.4 3.7 2.2 7.9 0.2 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) RRN7 PF11781.3 KFM01517.1 - 0.094 12.2 1.5 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-RING_5 PF14634.1 KFM01517.1 - 0.098 12.4 0.6 0.23 11.1 0.4 1.6 1 1 0 1 1 1 0 zinc-RING finger domain zf-HIT PF04438.11 KFM01517.1 - 0.1 12.2 4.0 0.17 11.5 0.3 2.1 2 0 0 2 2 2 0 HIT zinc finger zf-tcix PF14952.1 KFM01517.1 - 0.11 11.8 2.4 1.2 8.5 0.2 2.2 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding SprT-like PF10263.4 KFM01517.1 - 0.12 12.0 1.1 0.14 11.7 0.7 1.1 1 0 0 1 1 1 0 SprT-like family Ogr_Delta PF04606.7 KFM01517.1 - 0.13 11.9 2.0 5.5 6.7 0.1 2.2 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Zn_Tnp_IS1595 PF12760.2 KFM01517.1 - 0.14 11.9 3.3 0.49 10.2 2.2 1.8 1 1 0 1 1 1 0 Transposase zinc-ribbon domain C1_3 PF07649.7 KFM01517.1 - 0.17 11.9 0.7 1.1 9.3 0.0 2.1 2 0 0 2 2 2 0 C1-like domain zf-UBP PF02148.14 KFM01517.1 - 0.18 11.9 0.9 0.46 10.6 0.6 1.6 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-trcl PF13451.1 KFM01517.1 - 0.22 11.1 1.7 0.6 9.7 1.2 1.7 1 1 0 1 1 1 0 Probable zinc-binding domain Nudix_N_2 PF14803.1 KFM01517.1 - 0.31 10.7 3.6 6.5 6.5 0.1 2.4 2 0 0 2 2 2 0 Nudix N-terminal OrfB_Zn_ribbon PF07282.6 KFM01517.1 - 0.46 10.1 2.3 1.9 8.1 1.4 1.9 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zf-IS66 PF13005.2 KFM01517.1 - 0.82 9.6 3.6 9.2 6.3 1.0 2.4 2 1 0 2 2 2 0 zinc-finger binding domain of transposase IS66 A2L_zn_ribbon PF08792.5 KFM01517.1 - 0.86 9.1 4.2 1.1 8.7 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-C2H2_3 PF13878.1 KFM01517.1 - 2.2 7.9 5.8 17 5.0 1.7 2.9 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO zf-H2C2_5 PF13909.1 KFM01517.1 - 2.7 8.3 9.3 4.8 7.6 1.5 3.0 2 2 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.1 KFM01517.1 - 6.5 6.5 7.6 1.6 8.4 0.4 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.1 KFM01518.1 - 2.9e-63 207.1 31.7 1.5e-11 43.9 0.4 6.9 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.21 KFM01518.1 - 3.8e-48 159.0 35.3 3.4e-09 36.4 0.4 7.0 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KFM01518.1 - 2.3e-26 90.8 19.0 0.00018 21.2 0.1 6.3 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KFM01518.1 - 3.9e-25 86.2 32.1 3.8e-06 26.8 0.2 7.0 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM01518.1 - 8.3e-17 60.8 2.1 0.068 13.3 0.0 6.3 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 KFM01518.1 - 7e-10 38.8 20.7 0.0053 16.8 0.7 5.2 1 1 4 5 5 5 4 Drought induced 19 protein (Di19), zinc-binding zf-RING_3 PF14369.1 KFM01518.1 - 2.5e-09 36.9 22.8 0.2 11.6 0.1 6.1 6 0 0 6 6 6 3 zinc-finger Zn-ribbon_8 PF09723.5 KFM01518.1 - 4.5e-09 36.1 25.9 0.018 14.9 2.2 5.8 1 1 4 5 5 5 5 Zinc ribbon domain XPA_N PF01286.13 KFM01518.1 - 8.9e-09 34.8 16.8 0.58 9.8 0.1 6.2 6 0 0 6 6 6 2 XPA protein N-terminal zf-C2HC_2 PF13913.1 KFM01518.1 - 4e-08 32.7 24.6 0.00078 19.0 0.1 7.2 7 0 0 7 7 7 1 zinc-finger of a C2HC-type DZR PF12773.2 KFM01518.1 - 1.6e-07 31.0 18.1 0.023 14.5 4.8 3.9 1 1 2 3 3 3 3 Double zinc ribbon zf-ribbon_3 PF13248.1 KFM01518.1 - 1.7e-07 30.2 27.7 0.13 11.4 0.2 6.2 6 0 0 6 6 6 3 zinc-ribbon domain SprT-like PF10263.4 KFM01518.1 - 6.4e-07 29.1 8.9 0.14 11.7 0.1 3.1 1 1 1 3 3 3 3 SprT-like family C1_4 PF07975.7 KFM01518.1 - 7.5e-07 29.0 12.1 1.8 8.6 0.0 4.9 1 1 3 5 5 5 1 TFIIH C1-like domain DUF1610 PF07754.6 KFM01518.1 - 2.1e-06 27.7 39.5 0.12 12.4 0.7 6.3 6 0 0 6 6 6 3 Domain of unknown function (DUF1610) zf-met PF12874.2 KFM01518.1 - 2.4e-06 27.5 20.4 0.39 11.0 0.1 6.1 6 0 0 6 6 6 1 Zinc-finger of C2H2 type zf-ISL3 PF14690.1 KFM01518.1 - 3e-06 27.1 24.7 1 9.4 0.5 6.5 6 0 0 6 6 6 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Prok-RING_1 PF14446.1 KFM01518.1 - 3.3e-06 26.7 12.9 3.5 7.4 0.3 6.1 5 1 2 7 7 7 0 Prokaryotic RING finger family 1 zf-IS66 PF13005.2 KFM01518.1 - 7.8e-06 25.7 13.9 2.5 8.1 0.0 6.2 6 0 0 6 6 6 0 zinc-finger binding domain of transposase IS66 GAGA PF09237.6 KFM01518.1 - 7.9e-06 25.3 17.0 0.087 12.4 0.0 5.1 2 1 4 6 6 5 3 GAGA factor FYDLN_acid PF09538.5 KFM01518.1 - 1.2e-05 25.8 15.5 4.4 7.9 0.1 5.6 2 1 2 4 4 3 0 Protein of unknown function (FYDLN_acid) zf-AN1 PF01428.11 KFM01518.1 - 3e-05 23.7 19.0 1.9 8.4 0.2 6.1 5 1 1 6 6 6 1 AN1-like Zinc finger YhfH PF14149.1 KFM01518.1 - 3.4e-05 23.5 12.5 11 5.8 0.0 6.1 6 0 0 6 6 6 0 YhfH-like protein C1_1 PF00130.17 KFM01518.1 - 3.8e-05 23.3 10.3 0.31 10.7 1.2 4.5 1 1 4 5 5 5 1 Phorbol esters/diacylglycerol binding domain (C1 domain) CpXC PF14353.1 KFM01518.1 - 0.00012 21.9 16.1 2.6 8.0 0.6 5.8 2 2 2 4 4 4 0 CpXC protein DUF329 PF03884.9 KFM01518.1 - 0.00016 21.1 15.8 5 6.7 0.0 5.8 6 0 0 6 6 6 0 Domain of unknown function (DUF329) Zn_Tnp_IS1595 PF12760.2 KFM01518.1 - 0.00044 19.9 27.9 2.8 7.8 3.7 4.7 2 1 2 4 4 4 0 Transposase zinc-ribbon domain zinc_ribbon_5 PF13719.1 KFM01518.1 - 0.00059 19.3 20.5 6.9 6.3 0.1 6.5 5 2 0 5 5 5 0 zinc-ribbon domain zf-HIT PF04438.11 KFM01518.1 - 0.00085 18.9 26.5 1.5 8.5 0.2 6.1 6 0 0 6 6 6 1 HIT zinc finger BolA PF01722.13 KFM01518.1 - 0.00099 19.0 1.6 0.13 12.1 0.1 3.4 4 1 0 4 4 2 1 BolA-like protein zinc-ribbons_6 PF07191.7 KFM01518.1 - 0.0011 18.6 13.0 0.13 12.1 1.1 4.9 2 1 3 6 6 6 1 zinc-ribbons C1_3 PF07649.7 KFM01518.1 - 0.002 18.1 15.5 4.3 7.4 0.0 6.1 6 0 0 6 6 6 0 C1-like domain HypA PF01155.14 KFM01518.1 - 0.0022 17.6 15.2 1 9.0 0.5 4.3 1 1 2 3 3 3 1 Hydrogenase expression/synthesis hypA family zinc_ribbon_2 PF13240.1 KFM01518.1 - 0.0023 17.3 31.2 0.028 13.9 2.8 5.4 3 2 3 6 6 6 2 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KFM01518.1 - 0.0024 17.5 20.1 10 5.9 0.1 6.4 5 2 0 5 5 5 0 zinc-ribbon domain zf-RING_2 PF13639.1 KFM01518.1 - 0.0039 16.9 21.8 0.82 9.5 3.5 4.3 1 1 4 5 5 5 1 Ring finger domain TFIIS_C PF01096.13 KFM01518.1 - 0.0048 16.5 17.9 11 5.8 0.1 6.1 6 0 0 6 6 6 0 Transcription factor S-II (TFIIS) zf-TFIIB PF13453.1 KFM01518.1 - 0.0059 15.7 16.4 0.0068 15.5 0.3 4.3 4 1 1 5 5 4 1 Transcription factor zinc-finger zf-trcl PF13451.1 KFM01518.1 - 0.0075 15.8 13.7 7.8 6.2 0.0 5.8 6 0 0 6 6 6 0 Probable zinc-binding domain RRN7 PF11781.3 KFM01518.1 - 0.0088 15.5 13.0 16 5.0 0.0 5.8 6 0 0 6 6 6 0 RNA polymerase I-specific transcription initiation factor Rrn7 UPF0547 PF10571.4 KFM01518.1 - 0.011 15.4 29.8 2.6 7.8 0.2 6.1 6 0 0 6 6 6 0 Uncharacterised protein family UPF0547 A2L_zn_ribbon PF08792.5 KFM01518.1 - 0.016 14.6 20.7 0.99 8.9 0.1 5.8 6 0 0 6 6 6 0 A2L zinc ribbon domain DNA_RNApol_7kD PF03604.8 KFM01518.1 - 0.033 13.6 20.4 4.2 6.9 0.5 6.1 6 0 0 6 6 6 0 DNA directed RNA polymerase, 7 kDa subunit TerY-C PF15616.1 KFM01518.1 - 0.034 14.0 17.2 0.33 10.8 0.9 3.5 1 1 3 4 4 4 0 TerY-C metal binding domain Rad50_zn_hook PF04423.9 KFM01518.1 - 0.038 13.4 15.4 0.12 11.8 0.1 5.1 4 1 1 5 5 5 0 Rad50 zinc hook motif FYVE PF01363.16 KFM01518.1 - 0.047 13.6 19.7 2.6 8.0 0.6 4.4 1 1 2 3 3 3 0 FYVE zinc finger TF_Zn_Ribbon PF08271.7 KFM01518.1 - 0.049 12.9 25.6 5.7 6.3 0.1 6.1 6 0 0 6 6 6 0 TFIIB zinc-binding zf-Mss51 PF13824.1 KFM01518.1 - 0.051 13.4 28.7 2.2 8.1 0.4 5.6 2 1 4 6 6 6 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF164 PF02591.10 KFM01518.1 - 0.06 13.1 17.9 3.9 7.3 0.1 5.7 6 0 0 6 6 6 0 Putative zinc ribbon domain Zn_ribbon_recom PF13408.1 KFM01518.1 - 0.06 13.6 18.8 5.8 7.2 1.2 4.7 1 1 2 3 3 3 0 Recombinase zinc beta ribbon domain Ribosomal_L37ae PF01780.14 KFM01518.1 - 0.068 13.0 14.2 6.7 6.6 0.6 5.3 1 1 5 6 6 6 0 Ribosomal L37ae protein family HNH PF01844.18 KFM01518.1 - 0.073 12.9 20.4 0.72 9.7 0.3 6.3 6 1 0 6 6 6 0 HNH endonuclease LIM PF00412.17 KFM01518.1 - 0.081 13.0 13.8 9.3 6.4 0.8 4.8 1 1 2 4 4 4 0 LIM domain ADK_lid PF05191.9 KFM01518.1 - 0.097 12.3 21.5 5.1 6.8 0.1 6.1 6 0 0 6 6 6 0 Adenylate kinase, active site lid IBD PF10416.4 KFM01518.1 - 0.12 12.2 0.2 3 7.6 0.0 3.2 1 1 4 5 5 4 0 Transcription-initiator DNA-binding domain IBD Rep_fac-A_C PF08646.5 KFM01518.1 - 0.18 11.5 7.7 14 5.3 1.3 3.6 1 1 3 4 4 3 0 Replication factor-A C terminal domain zf-LYAR PF08790.6 KFM01518.1 - 0.19 11.4 17.1 0.4 10.4 0.2 5.4 6 0 0 6 6 6 0 LYAR-type C2HC zinc finger zf-C4_Topoisom PF01396.14 KFM01518.1 - 0.21 11.1 18.4 8.2 6.0 0.0 5.8 6 0 0 6 6 6 0 Topoisomerase DNA binding C4 zinc finger Rubredoxin PF00301.15 KFM01518.1 - 0.25 11.2 21.1 4.4 7.2 2.6 5.4 4 1 1 5 5 5 0 Rubredoxin Elf1 PF05129.8 KFM01518.1 - 0.29 10.8 13.8 2.3 7.9 0.1 4.3 1 1 4 5 5 5 0 Transcription elongation factor Elf1 like Prok-RING_4 PF14447.1 KFM01518.1 - 0.31 10.6 17.9 10 5.7 0.1 5.5 4 1 1 5 5 5 0 Prokaryotic RING finger family 4 DUF899 PF05988.7 KFM01518.1 - 0.61 9.4 2.7 28 4.0 0.0 3.0 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF899) zf-UBR PF02207.15 KFM01518.1 - 0.8 9.4 16.2 7.1 6.4 0.7 5.1 1 1 3 4 4 4 0 Putative zinc finger in N-recognin (UBR box) COX5B PF01215.14 KFM01518.1 - 0.84 9.3 15.5 8.5 6.0 0.0 5.0 1 1 5 6 6 6 0 Cytochrome c oxidase subunit Vb PolC_DP2 PF03833.8 KFM01518.1 - 0.97 7.0 8.8 0.15 9.7 1.9 1.9 1 1 1 2 2 2 0 DNA polymerase II large subunit DP2 Sgf11 PF08209.6 KFM01518.1 - 1.4 8.3 18.9 6.4 6.1 0.0 5.7 6 0 0 6 6 6 0 Sgf11 (transcriptional regulation protein) zf-RING_5 PF14634.1 KFM01518.1 - 1.5 8.6 24.6 15 5.3 0.2 5.6 3 3 0 4 4 4 0 zinc-RING finger domain zf-C2H2_2 PF12756.2 KFM01518.1 - 2.5 8.2 13.9 18 5.4 0.0 4.6 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) PHF5 PF03660.9 KFM01518.1 - 2.7 8.1 7.5 3.2 7.8 1.2 2.7 1 1 1 3 3 3 0 PHF5-like protein Ogr_Delta PF04606.7 KFM01518.1 - 3 7.5 22.8 2 8.1 1.6 4.7 2 2 2 4 4 4 0 Ogr/Delta-like zinc finger Nudix_N_2 PF14803.1 KFM01518.1 - 4.5 7.0 19.0 26 4.5 0.1 6.0 6 0 0 6 6 6 0 Nudix N-terminal DUF2256 PF10013.4 KFM01518.1 - 4.5 7.1 18.2 21 4.9 0.1 5.7 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF2225 PF09986.4 KFM01518.1 - 6.1 6.2 16.5 22 4.3 0.1 4.6 2 1 3 5 5 4 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-CSL PF05207.8 KFM01518.1 - 6.4 6.3 20.8 22 4.6 2.0 4.5 1 1 3 4 4 4 0 CSL zinc finger Cys_rich_CPCC PF14206.1 KFM01518.1 - 6.9 6.3 15.0 17 5.0 0.0 4.9 5 0 0 5 5 5 0 Cysteine-rich CPCC zf-CHCC PF10276.4 KFM01518.1 - 7.5 6.4 22.5 3.3 7.6 0.1 5.8 6 0 0 6 6 6 0 Zinc-finger domain IBR PF01485.16 KFM01518.1 - 8.3 6.3 20.2 23 4.9 0.1 5.3 2 1 1 4 4 4 0 IBR domain zf-C2H2 PF00096.21 KFM01520.1 - 1.2e-48 160.6 65.7 4.1e-08 33.1 0.5 8.1 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM01520.1 - 3.2e-46 153.4 62.0 6.1e-08 32.5 3.4 8.8 9 0 0 9 9 9 7 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM01520.1 - 3.7e-26 89.4 61.4 0.0008 19.5 0.4 8.1 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM01520.1 - 2e-22 78.2 43.2 0.00083 19.1 0.5 8.2 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM01520.1 - 8.1e-20 70.3 27.3 0.014 15.5 0.2 8.1 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 KFM01520.1 - 7.7e-09 35.3 35.1 0.0055 16.6 1.8 7.4 6 2 0 6 6 6 3 Zinc ribbon domain zinc_ribbon_2 PF13240.1 KFM01520.1 - 3.5e-06 26.3 23.3 0.00054 19.3 0.0 6.2 6 2 0 6 6 6 2 zinc-ribbon domain CpXC PF14353.1 KFM01520.1 - 7.2e-06 25.9 19.5 0.96 9.4 0.7 6.8 3 2 2 5 5 5 1 CpXC protein zf-C2HC_2 PF13913.1 KFM01520.1 - 6.4e-05 22.4 51.0 0.16 11.6 0.1 8.2 8 0 0 8 8 8 2 zinc-finger of a C2HC-type zf-met PF12874.2 KFM01520.1 - 9.4e-05 22.4 38.5 0.43 10.8 0.1 7.9 8 0 0 8 8 8 3 Zinc-finger of C2H2 type DZR PF12773.2 KFM01520.1 - 0.00018 21.2 27.4 38 4.2 10.5 4.9 1 1 1 2 2 2 0 Double zinc ribbon C1_3 PF07649.7 KFM01520.1 - 0.0007 19.5 21.6 1.8 8.6 0.1 6.6 7 0 0 7 7 6 1 C1-like domain Prok-RING_1 PF14446.1 KFM01520.1 - 0.0016 18.1 16.9 5.6 6.7 0.0 7.2 7 1 0 7 7 6 0 Prokaryotic RING finger family 1 Zn_Tnp_IS1595 PF12760.2 KFM01520.1 - 0.0068 16.1 2.6 0.0068 16.1 1.8 5.4 4 2 1 5 5 5 1 Transposase zinc-ribbon domain C1_4 PF07975.7 KFM01520.1 - 0.0089 16.0 24.5 3.4 7.7 1.0 5.6 2 1 4 6 6 6 1 TFIIH C1-like domain zinc_ribbon_4 PF13717.1 KFM01520.1 - 0.009 15.6 26.0 0.039 13.6 0.9 6.8 6 2 0 7 7 6 1 zinc-ribbon domain zf-CHY PF05495.7 KFM01520.1 - 0.011 15.8 27.1 0.15 12.2 2.0 4.1 1 1 2 3 3 3 0 CHY zinc finger Elf1 PF05129.8 KFM01520.1 - 0.013 15.1 0.3 0.013 15.1 0.2 4.7 2 1 1 4 4 4 0 Transcription elongation factor Elf1 like zinc_ribbon_5 PF13719.1 KFM01520.1 - 0.024 14.2 1.3 0.024 14.2 0.9 6.8 7 1 0 7 7 6 0 zinc-ribbon domain HNH PF01844.18 KFM01520.1 - 0.039 13.8 32.2 0.056 13.3 0.8 7.1 7 1 1 8 8 7 0 HNH endonuclease zf-AN1 PF01428.11 KFM01520.1 - 0.047 13.5 33.3 3.9 7.4 0.0 7.5 6 2 2 8 8 7 0 AN1-like Zinc finger FYDLN_acid PF09538.5 KFM01520.1 - 0.05 14.1 16.4 3.8 8.1 0.3 6.3 1 1 3 4 4 4 0 Protein of unknown function (FYDLN_acid) LIM PF00412.17 KFM01520.1 - 0.062 13.3 23.1 1.5 8.9 0.5 5.1 3 1 2 5 5 5 0 LIM domain zf-IS66 PF13005.2 KFM01520.1 - 0.083 12.8 18.1 16 5.5 0.0 6.9 7 0 0 7 7 7 0 zinc-finger binding domain of transposase IS66 XPA_N PF01286.13 KFM01520.1 - 0.16 11.7 28.1 3.3 7.4 0.1 7.2 8 0 0 8 8 7 0 XPA protein N-terminal zf-ribbon_3 PF13248.1 KFM01520.1 - 0.22 10.7 28.8 0.98 8.7 0.1 7.3 8 0 0 8 8 8 0 zinc-ribbon domain TFIIS_C PF01096.13 KFM01520.1 - 0.22 11.1 26.7 5.8 6.6 0.1 7.0 7 0 0 7 7 7 0 Transcription factor S-II (TFIIS) zf-Di19 PF05605.7 KFM01520.1 - 0.26 11.4 27.6 0.17 12.0 1.1 5.2 2 2 4 6 6 5 0 Drought induced 19 protein (Di19), zinc-binding DNA_RNApol_7kD PF03604.8 KFM01520.1 - 0.41 10.1 31.4 7 6.2 0.1 7.3 7 0 0 7 7 7 0 DNA directed RNA polymerase, 7 kDa subunit Zn_ribbon_recom PF13408.1 KFM01520.1 - 0.54 10.5 40.0 0.26 11.5 2.7 6.3 2 1 3 5 5 4 0 Recombinase zinc beta ribbon domain ADK_lid PF05191.9 KFM01520.1 - 0.92 9.2 0.1 0.92 9.2 0.1 7.0 7 1 0 7 7 7 0 Adenylate kinase, active site lid GAGA PF09237.6 KFM01520.1 - 1.5 8.4 11.3 0.93 9.1 0.8 3.6 3 2 1 4 4 3 0 GAGA factor zf-RING_3 PF14369.1 KFM01520.1 - 1.6 8.7 30.2 1.4 8.9 0.1 6.8 7 1 0 7 7 7 0 zinc-finger zf-trcl PF13451.1 KFM01520.1 - 1.9 8.1 30.7 4.5 6.9 0.1 7.1 7 0 0 7 7 7 0 Probable zinc-binding domain Yippee-Mis18 PF03226.9 KFM01520.1 - 2 8.5 15.3 0.27 11.3 0.3 3.9 1 1 1 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HypA PF01155.14 KFM01520.1 - 3.1 7.5 25.7 25 4.6 5.1 4.6 1 1 3 4 4 4 0 Hydrogenase expression/synthesis hypA family TF_Zn_Ribbon PF08271.7 KFM01520.1 - 3.8 6.9 28.9 4.9 6.5 0.1 6.1 5 2 0 5 5 5 0 TFIIB zinc-binding A2L_zn_ribbon PF08792.5 KFM01520.1 - 3.8 7.0 25.0 5.5 6.5 0.0 7.0 8 0 0 8 8 7 0 A2L zinc ribbon domain COX5B PF01215.14 KFM01520.1 - 5.1 6.7 21.2 11 5.7 0.1 6.0 1 1 5 7 7 7 0 Cytochrome c oxidase subunit Vb DUF164 PF02591.10 KFM01520.1 - 6.1 6.7 27.7 3 7.7 0.1 6.5 7 0 0 7 7 6 0 Putative zinc ribbon domain DUF1163 PF06651.6 KFM01520.1 - 7.9 6.1 8.2 5.2 6.7 0.1 3.5 2 1 1 4 4 3 0 Protein of unknown function (DUF1163) YhfH PF14149.1 KFM01520.1 - 7.9 6.3 20.9 27 4.6 0.0 6.8 8 0 0 8 8 7 0 YhfH-like protein zf-HIT PF04438.11 KFM01520.1 - 8.3 6.1 35.1 4.1 7.1 0.1 6.7 8 0 0 8 8 7 0 HIT zinc finger PHD PF00628.24 KFM01520.1 - 8.9 6.0 23.7 2.6 7.8 3.4 5.0 3 1 2 5 5 5 0 PHD-finger zf-H2C2_2 PF13465.1 KFM01521.1 - 2.7e-76 248.3 50.3 1.3e-10 40.9 0.5 9.0 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.21 KFM01521.1 - 1.5e-62 204.2 61.6 2.9e-09 36.7 0.8 8.3 9 0 0 9 9 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM01521.1 - 1.5e-39 131.4 45.8 5e-05 23.3 0.5 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM01521.1 - 1.4e-38 129.5 32.3 1.4e-05 24.8 0.1 8.2 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM01521.1 - 1.8e-26 91.6 18.8 0.0019 18.2 0.1 8.1 8 0 0 8 8 8 7 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 KFM01521.1 - 4.2e-12 45.8 39.8 0.0018 18.1 2.2 7.5 2 2 5 7 7 7 6 Zinc ribbon domain C1_3 PF07649.7 KFM01521.1 - 2.9e-10 39.9 17.0 4 7.5 0.0 8.2 8 0 0 8 8 8 0 C1-like domain XPA_N PF01286.13 KFM01521.1 - 3.5e-10 39.3 28.5 0.38 10.4 0.5 8.1 8 0 0 8 8 8 3 XPA protein N-terminal zf-met PF12874.2 KFM01521.1 - 1.9e-09 37.3 41.9 0.16 12.2 0.2 8.1 8 0 0 8 8 8 4 Zinc-finger of C2H2 type C1_1 PF00130.17 KFM01521.1 - 3.2e-09 36.3 10.7 0.085 12.5 0.1 5.4 1 1 6 7 7 7 7 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_4 PF07975.7 KFM01521.1 - 1.5e-08 34.4 24.3 0.33 10.9 0.7 6.9 1 1 6 7 7 7 4 TFIIH C1-like domain Prok-RING_1 PF14446.1 KFM01521.1 - 7.4e-08 32.0 13.5 20 5.0 0.0 8.0 8 0 0 8 8 8 0 Prokaryotic RING finger family 1 CpXC PF14353.1 KFM01521.1 - 1.3e-07 31.6 22.8 0.36 10.7 0.5 7.7 4 3 1 5 5 5 2 CpXC protein FYDLN_acid PF09538.5 KFM01521.1 - 1.4e-07 32.0 17.9 3.3 8.3 0.1 7.2 1 1 6 7 7 7 0 Protein of unknown function (FYDLN_acid) zf-ribbon_3 PF13248.1 KFM01521.1 - 2.8e-07 29.5 29.9 0.69 9.1 0.2 7.6 8 0 0 8 8 8 5 zinc-ribbon domain zinc_ribbon_5 PF13719.1 KFM01521.1 - 9.6e-07 28.2 22.5 0.5 10.0 0.0 7.4 7 1 1 8 8 8 2 zinc-ribbon domain zf-Di19 PF05605.7 KFM01521.1 - 1.1e-06 28.6 28.3 0.0096 16.0 1.2 6.3 1 1 4 6 6 6 3 Drought induced 19 protein (Di19), zinc-binding Zn_Tnp_IS1595 PF12760.2 KFM01521.1 - 6.9e-06 25.7 39.1 0.017 14.8 2.8 5.6 3 2 2 6 6 6 4 Transposase zinc-ribbon domain zf-HIT PF04438.11 KFM01521.1 - 8.4e-06 25.3 36.2 2.6 7.7 0.3 8.1 8 0 0 8 8 8 0 HIT zinc finger DNA_RNApol_7kD PF03604.8 KFM01521.1 - 1.2e-05 24.6 24.6 6.4 6.3 0.0 8.1 8 0 0 8 8 8 0 DNA directed RNA polymerase, 7 kDa subunit zf-IS66 PF13005.2 KFM01521.1 - 1.3e-05 25.0 18.0 3.8 7.5 0.0 7.7 8 0 0 8 8 8 0 zinc-finger binding domain of transposase IS66 DUF164 PF02591.10 KFM01521.1 - 1.6e-05 24.6 23.1 0.61 9.9 0.1 7.8 8 0 0 8 8 8 1 Putative zinc ribbon domain zf-RING_3 PF14369.1 KFM01521.1 - 2.6e-05 24.1 26.0 1 9.4 0.1 7.5 8 0 0 8 8 8 1 zinc-finger COX5B PF01215.14 KFM01521.1 - 2.6e-05 23.8 23.5 1.7 8.3 0.3 6.9 1 1 5 7 7 7 1 Cytochrome c oxidase subunit Vb DZR PF12773.2 KFM01521.1 - 2.6e-05 23.9 28.8 1.5e+04 -11.2 20.0 5.3 1 1 0 1 1 0 0 Double zinc ribbon zf-LYAR PF08790.6 KFM01521.1 - 5.8e-05 22.7 26.5 1 9.1 0.1 7.6 8 0 0 8 8 7 1 LYAR-type C2HC zinc finger zinc_ribbon_4 PF13717.1 KFM01521.1 - 9.8e-05 21.9 26.2 0.68 9.6 0.0 7.4 6 2 1 7 7 6 2 zinc-ribbon domain zf-AN1 PF01428.11 KFM01521.1 - 0.00017 21.3 30.7 7.9 6.4 0.1 8.0 7 1 1 8 8 8 0 AN1-like Zinc finger zf-ISL3 PF14690.1 KFM01521.1 - 0.00022 21.1 32.4 1.7 8.7 0.1 8.1 7 1 1 8 8 8 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-trcl PF13451.1 KFM01521.1 - 0.00052 19.5 23.2 14 5.4 0.0 7.8 8 0 0 8 8 8 0 Probable zinc-binding domain TFIIS_C PF01096.13 KFM01521.1 - 0.00066 19.2 32.1 5.9 6.6 0.1 8.1 8 0 0 8 8 8 0 Transcription factor S-II (TFIIS) zf-C2HC_2 PF13913.1 KFM01521.1 - 0.00087 18.8 1.2 0.019 14.6 0.0 7.4 8 0 0 8 8 7 2 zinc-finger of a C2HC-type YhfH PF14149.1 KFM01521.1 - 0.0015 18.2 24.8 18 5.2 0.1 7.9 8 0 0 8 8 8 0 YhfH-like protein zf-H2C2_5 PF13909.1 KFM01521.1 - 0.0021 18.2 42.2 3 8.2 0.0 9.1 8 1 0 8 8 8 0 C2H2-type zinc-finger domain Zn_ribbon_recom PF13408.1 KFM01521.1 - 0.0022 18.2 27.9 9.1 6.6 3.7 6.5 1 1 3 5 5 5 0 Recombinase zinc beta ribbon domain zinc_ribbon_2 PF13240.1 KFM01521.1 - 0.0029 17.0 36.4 0.0051 16.2 0.7 6.4 6 2 0 6 6 5 3 zinc-ribbon domain zinc-ribbons_6 PF07191.7 KFM01521.1 - 0.0043 16.8 22.6 0.78 9.5 0.1 5.7 2 1 5 7 7 7 2 zinc-ribbons DUF329 PF03884.9 KFM01521.1 - 0.0051 16.3 22.9 8.5 6.0 0.0 7.3 7 1 1 8 8 8 0 Domain of unknown function (DUF329) DUF2072 PF09845.4 KFM01521.1 - 0.008 16.1 25.6 9 6.2 1.3 7.0 5 2 3 8 8 8 0 Zn-ribbon containing protein (DUF2072) UPF0547 PF10571.4 KFM01521.1 - 0.0084 15.7 37.0 0.86 9.3 0.2 7.4 8 0 0 8 8 7 2 Uncharacterised protein family UPF0547 TF_Zn_Ribbon PF08271.7 KFM01521.1 - 0.011 15.0 34.7 1.5 8.1 0.2 7.5 8 0 0 8 8 8 0 TFIIB zinc-binding A2L_zn_ribbon PF08792.5 KFM01521.1 - 0.013 14.9 32.9 6 6.4 0.2 7.8 8 0 0 8 8 8 0 A2L zinc ribbon domain GAGA PF09237.6 KFM01521.1 - 0.015 14.8 14.8 1.9 8.1 0.0 6.0 1 1 6 7 7 7 0 GAGA factor DUF1610 PF07754.6 KFM01521.1 - 0.022 14.8 56.0 0.69 10.0 1.6 7.9 8 0 0 8 8 8 0 Domain of unknown function (DUF1610) zf-CSL PF05207.8 KFM01521.1 - 0.025 14.0 24.8 1.3 8.6 0.6 5.4 1 1 6 7 7 7 0 CSL zinc finger Elf1 PF05129.8 KFM01521.1 - 0.031 13.9 20.0 0.31 10.7 0.6 5.2 1 1 6 7 7 7 0 Transcription elongation factor Elf1 like FdhE PF04216.7 KFM01521.1 - 0.031 14.0 1.2 0.031 14.0 0.9 3.8 1 1 2 4 4 4 0 Protein involved in formate dehydrogenase formation zf-Mss51 PF13824.1 KFM01521.1 - 0.031 14.1 39.5 2 8.3 0.3 7.3 1 1 4 5 5 5 0 Zinc-finger of mitochondrial splicing suppressor 51 LIM PF00412.17 KFM01521.1 - 0.032 14.2 23.8 7.7 6.6 0.4 6.7 1 1 5 7 7 7 0 LIM domain NuA4 PF09340.5 KFM01521.1 - 0.034 13.7 5.5 4.6 6.9 0.0 4.3 3 3 2 5 5 5 0 Histone acetyltransferase subunit NuA4 HypA PF01155.14 KFM01521.1 - 0.04 13.6 25.1 1.5 8.5 0.7 4.7 1 1 4 5 5 5 0 Hydrogenase expression/synthesis hypA family zf-BED PF02892.10 KFM01521.1 - 0.049 13.3 37.3 0.59 9.9 0.8 7.7 1 1 6 7 7 7 0 BED zinc finger Mut7-C PF01927.11 KFM01521.1 - 0.18 11.7 22.8 4.1 7.3 0.6 5.5 1 1 6 7 7 7 0 Mut7-C RNAse domain ADK_lid PF05191.9 KFM01521.1 - 0.44 10.2 30.2 1.1 8.9 0.2 6.9 7 1 0 7 7 7 0 Adenylate kinase, active site lid Cys_rich_CPXG PF14255.1 KFM01521.1 - 0.77 9.6 11.1 55 3.6 0.1 5.3 5 0 0 5 5 5 0 Cysteine-rich CPXCG GF_recep_IV PF14843.1 KFM01521.1 - 0.88 9.1 20.3 2.6 7.6 1.6 3.4 1 1 3 4 4 4 0 Growth factor receptor domain IV TerY-C PF15616.1 KFM01521.1 - 1.6 8.6 20.3 1.6 8.6 0.8 3.8 1 1 3 4 4 4 0 TerY-C metal binding domain Sgf11 PF08209.6 KFM01521.1 - 1.9 7.8 30.3 4 6.8 0.1 7.6 8 0 0 8 8 8 0 Sgf11 (transcriptional regulation protein) Ribosomal_S27e PF01667.12 KFM01521.1 - 5 6.7 21.2 30 4.2 0.0 7.3 8 0 0 8 8 8 0 Ribosomal protein S27 DUF1187 PF06688.6 KFM01521.1 - 5.3 7.2 7.2 9.1 6.4 0.5 3.8 3 1 1 4 4 3 0 Protein of unknown function (DUF1187) Gly-zipper_Omp PF13488.1 KFM01522.1 - 1.2 8.8 20.0 5 6.8 2.9 3.4 2 2 0 2 2 2 0 Glycine zipper Gly-zipper_YMGG PF13441.1 KFM01522.1 - 5.9 6.4 20.6 3 7.4 2.7 3.2 2 1 0 2 2 2 0 YMGG-like Gly-zipper zf-H2C2_2 PF13465.1 KFM01523.1 - 1e-47 158.1 59.8 8.9e-10 38.3 0.7 6.6 7 0 0 7 7 6 6 Zinc-finger double domain zf-C2H2 PF00096.21 KFM01523.1 - 3.4e-35 118.2 53.9 5.6e-07 29.5 0.4 7.1 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KFM01523.1 - 2e-20 71.9 32.3 0.0012 18.6 0.1 6.4 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KFM01523.1 - 2.2e-18 65.1 50.3 0.00016 21.7 2.1 7.0 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM01523.1 - 2e-08 34.0 23.2 0.018 15.1 0.0 5.8 5 1 1 6 6 6 5 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 KFM01523.1 - 1.2e-06 28.3 30.2 0.014 15.3 2.0 5.5 3 2 1 4 4 4 2 Zinc ribbon domain zf-Di19 PF05605.7 KFM01523.1 - 1.8e-05 24.7 27.8 0.09 12.9 1.4 3.8 3 2 0 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding C1_1 PF00130.17 KFM01523.1 - 5.8e-05 22.7 26.3 0.0062 16.2 2.9 4.2 3 1 1 4 4 4 3 Phorbol esters/diacylglycerol binding domain (C1 domain) GAGA PF09237.6 KFM01523.1 - 0.00027 20.4 18.9 0.00032 20.2 0.3 4.5 2 1 3 5 5 5 2 GAGA factor zf-met PF12874.2 KFM01523.1 - 0.0003 20.8 33.9 0.068 13.4 0.1 5.7 6 0 0 6 6 5 3 Zinc-finger of C2H2 type C1_3 PF07649.7 KFM01523.1 - 0.0015 18.5 20.2 0.78 9.8 0.1 6.2 6 0 0 6 6 6 1 C1-like domain PHD PF00628.24 KFM01523.1 - 0.014 15.1 1.1 0.014 15.1 0.8 4.0 2 1 1 3 3 3 0 PHD-finger BolA PF01722.13 KFM01523.1 - 0.057 13.3 6.2 4.3 7.3 0.1 3.1 3 0 0 3 3 3 0 BolA-like protein zf-AN1 PF01428.11 KFM01523.1 - 0.067 13.0 30.4 3.3 7.6 0.2 6.3 6 0 0 6 6 6 0 AN1-like Zinc finger LIM PF00412.17 KFM01523.1 - 0.12 12.5 25.0 2.7 8.1 0.1 4.7 1 1 4 5 5 5 0 LIM domain C1_4 PF07975.7 KFM01523.1 - 0.17 11.8 26.8 6.6 6.8 0.3 5.2 1 1 4 5 5 5 0 TFIIH C1-like domain zinc_ribbon_5 PF13719.1 KFM01523.1 - 0.64 9.6 30.4 2.7 7.6 0.3 6.1 6 0 0 6 6 6 0 zinc-ribbon domain zf-RING_5 PF14634.1 KFM01523.1 - 0.65 9.7 27.5 3.4 7.4 6.2 4.9 1 1 3 4 4 4 0 zinc-RING finger domain FYDLN_acid PF09538.5 KFM01523.1 - 0.67 10.5 16.7 18 5.9 0.4 5.4 1 1 3 4 4 4 0 Protein of unknown function (FYDLN_acid) zinc_ribbon_4 PF13717.1 KFM01523.1 - 1.2 8.9 30.1 3.9 7.2 0.2 6.1 6 0 0 6 6 6 0 zinc-ribbon domain zf-RING_3 PF14369.1 KFM01523.1 - 1.2 9.1 25.4 8.3 6.5 0.0 5.9 5 1 1 6 6 6 0 zinc-finger XPA_N PF01286.13 KFM01523.1 - 2.1 8.0 0.0 2.1 8.0 0.0 5.8 6 0 0 6 6 6 0 XPA protein N-terminal Zn_Tnp_IS1595 PF12760.2 KFM01523.1 - 2.1 8.1 38.2 1.9 8.3 3.0 4.8 2 2 4 6 6 6 0 Transposase zinc-ribbon domain zinc-ribbons_6 PF07191.7 KFM01523.1 - 2.2 8.1 22.0 9.7 6.0 0.1 5.3 4 2 1 5 5 5 0 zinc-ribbons zf-LYAR PF08790.6 KFM01523.1 - 2.7 7.7 18.0 13 5.6 0.3 5.3 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger zf-C2HC_2 PF13913.1 KFM01523.1 - 3.4 7.4 35.6 0.95 9.2 0.2 6.1 7 0 0 7 7 6 0 zinc-finger of a C2HC-type zf-HIT PF04438.11 KFM01523.1 - 3.9 7.2 36.7 1.6 8.4 1.2 6.1 6 0 0 6 6 6 0 HIT zinc finger Mut7-C PF01927.11 KFM01523.1 - 4.9 7.1 22.6 2.4 8.1 0.2 4.3 1 1 3 4 4 4 0 Mut7-C RNAse domain zf-H2C2_2 PF13465.1 KFM01524.1 - 3.5e-19 68.0 16.8 9.2e-11 41.4 0.6 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFM01524.1 - 2.3e-14 52.7 14.6 3.2e-06 27.1 0.5 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM01524.1 - 1.3e-06 28.2 11.0 0.018 15.3 0.3 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM01524.1 - 4.2e-06 26.4 11.0 0.074 12.9 0.5 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 KFM01524.1 - 3.7e-05 23.5 7.4 0.071 13.0 0.8 3.1 1 1 1 2 2 2 2 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 KFM01524.1 - 0.00027 20.6 6.4 0.13 12.1 0.8 2.4 2 1 0 2 2 2 2 Transposase zinc-ribbon domain XPA_N PF01286.13 KFM01524.1 - 0.00058 19.4 8.3 1 9.1 0.5 3.1 3 0 0 3 3 3 2 XPA protein N-terminal zinc_ribbon_5 PF13719.1 KFM01524.1 - 0.00099 18.6 4.2 0.36 10.4 0.2 3.1 1 1 1 2 2 2 1 zinc-ribbon domain zf-C2H2_jaz PF12171.3 KFM01524.1 - 0.0015 18.6 3.6 1.9 8.7 0.0 3.2 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding C1_1 PF00130.17 KFM01524.1 - 0.0027 17.4 1.8 0.02 14.5 0.7 2.2 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-LYAR PF08790.6 KFM01524.1 - 0.0042 16.7 6.7 3.1 7.5 0.1 3.2 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger LIM PF00412.17 KFM01524.1 - 0.0053 16.8 2.8 0.072 13.1 0.1 2.5 1 1 1 2 2 2 1 LIM domain zf-trcl PF13451.1 KFM01524.1 - 0.0067 16.0 7.1 0.84 9.3 0.1 3.1 3 0 0 3 3 3 2 Probable zinc-binding domain zf-ribbon_3 PF13248.1 KFM01524.1 - 0.0085 15.2 8.0 1.8 7.8 0.1 3.2 3 0 0 3 3 3 1 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KFM01524.1 - 0.02 14.5 7.5 1.7 8.4 1.7 3.1 2 1 1 3 3 3 0 zinc-ribbon domain TFIIS_C PF01096.13 KFM01524.1 - 0.024 14.2 8.5 0.76 9.4 0.2 3.1 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) Elf1 PF05129.8 KFM01524.1 - 0.033 13.8 0.6 0.033 13.8 0.4 1.6 1 1 1 2 2 1 0 Transcription elongation factor Elf1 like zf-AN1 PF01428.11 KFM01524.1 - 0.038 13.8 8.3 1.7 8.5 0.2 3.1 3 0 0 3 3 3 0 AN1-like Zinc finger DZR PF12773.2 KFM01524.1 - 0.046 13.5 4.6 0.39 10.5 3.2 2.1 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_3 PF14369.1 KFM01524.1 - 0.047 13.6 8.0 1.5 8.8 0.1 3.0 3 0 0 3 3 3 0 zinc-finger zf-CHY PF05495.7 KFM01524.1 - 0.05 13.7 1.5 0.094 12.8 1.0 1.6 1 1 0 1 1 1 0 CHY zinc finger DUF164 PF02591.10 KFM01524.1 - 0.074 12.8 5.1 5.4 6.9 0.1 3.0 3 0 0 3 3 3 0 Putative zinc ribbon domain ADK_lid PF05191.9 KFM01524.1 - 0.088 12.4 4.9 6.6 6.4 0.1 3.1 3 0 0 3 3 3 0 Adenylate kinase, active site lid Prok-RING_1 PF14446.1 KFM01524.1 - 0.089 12.5 3.0 24 4.7 0.0 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 DNA_RNApol_7kD PF03604.8 KFM01524.1 - 0.16 11.5 8.7 1.9 7.9 0.3 3.1 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit CpXC PF14353.1 KFM01524.1 - 0.16 11.9 3.6 1.3 8.9 0.2 2.9 1 1 1 2 2 2 0 CpXC protein zf-Di19 PF05605.7 KFM01524.1 - 0.18 11.9 2.1 5.1 7.2 0.8 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding IBR PF01485.16 KFM01524.1 - 0.22 11.4 5.7 6.4 6.7 0.6 2.7 1 1 0 2 2 2 0 IBR domain YhfH PF14149.1 KFM01524.1 - 0.24 11.2 8.8 6.6 6.6 0.2 3.1 3 0 0 3 3 3 0 YhfH-like protein zf-IS66 PF13005.2 KFM01524.1 - 0.25 11.3 3.4 33 4.5 0.0 3.2 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 zinc-ribbons_6 PF07191.7 KFM01524.1 - 0.26 11.1 2.0 18 5.2 1.4 2.7 1 1 0 1 1 1 0 zinc-ribbons HypA PF01155.14 KFM01524.1 - 0.28 10.8 2.2 0.59 9.8 0.7 1.9 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family COX5B PF01215.14 KFM01524.1 - 0.3 10.7 4.1 9.6 5.8 0.1 2.9 1 1 2 3 3 3 0 Cytochrome c oxidase subunit Vb zf-UBR PF02207.15 KFM01524.1 - 0.34 10.6 3.7 8.8 6.1 0.1 2.4 1 1 1 2 2 2 0 Putative zinc finger in N-recognin (UBR box) A2L_zn_ribbon PF08792.5 KFM01524.1 - 0.34 10.4 10.5 3.7 7.1 0.4 3.1 3 0 0 3 3 3 0 A2L zinc ribbon domain zf-MYND PF01753.13 KFM01524.1 - 0.37 10.7 3.2 1.4 8.8 1.4 2.2 1 1 1 2 2 2 0 MYND finger zf-ISL3 PF14690.1 KFM01524.1 - 0.42 10.6 10.6 4.1 7.5 0.8 3.3 2 2 1 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Mut7-C PF01927.11 KFM01524.1 - 0.46 10.4 3.4 3.4 7.6 0.2 2.8 1 1 1 2 2 2 0 Mut7-C RNAse domain FYDLN_acid PF09538.5 KFM01524.1 - 0.48 11.0 2.3 12 6.5 0.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) C1_4 PF07975.7 KFM01524.1 - 0.51 10.3 4.5 8.4 6.4 2.0 2.6 1 1 0 1 1 1 0 TFIIH C1-like domain Zn_ribbon_recom PF13408.1 KFM01524.1 - 0.52 10.6 8.6 7.9 6.8 4.2 2.6 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-RING_5 PF14634.1 KFM01524.1 - 0.66 9.7 3.8 11 5.8 2.6 2.5 1 1 0 1 1 1 0 zinc-RING finger domain zf-CSL PF05207.8 KFM01524.1 - 0.68 9.4 3.7 1.4 8.5 0.1 2.2 1 1 0 2 2 2 0 CSL zinc finger Ogr_Delta PF04606.7 KFM01524.1 - 0.71 9.5 5.3 0.6 9.8 0.9 2.1 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zf-HIT PF04438.11 KFM01524.1 - 0.74 9.5 7.1 0.52 9.9 0.3 2.8 3 0 0 3 3 3 0 HIT zinc finger zf-HYPF PF07503.7 KFM01524.1 - 0.79 9.1 6.4 13 5.3 0.1 3.2 3 0 0 3 3 3 0 HypF finger zinc_ribbon_2 PF13240.1 KFM01524.1 - 0.82 9.2 12.5 11 5.7 0.2 3.1 2 1 1 3 3 3 0 zinc-ribbon domain ZZ PF00569.12 KFM01524.1 - 0.87 9.1 0.1 0.87 9.1 0.1 2.4 3 0 0 3 3 2 0 Zinc finger, ZZ type Nudix_N_2 PF14803.1 KFM01524.1 - 0.88 9.3 6.3 22 4.8 0.1 3.4 3 0 0 3 3 3 0 Nudix N-terminal zf-Mss51 PF13824.1 KFM01524.1 - 1 9.2 7.6 9.8 6.1 0.1 2.9 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 UPF0547 PF10571.4 KFM01524.1 - 1.3 8.7 11.1 2.8 7.7 0.2 3.1 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 OrfB_Zn_ribbon PF07282.6 KFM01524.1 - 1.4 8.6 6.3 6.7 6.4 0.6 2.6 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zf-tcix PF14952.1 KFM01524.1 - 1.5 8.2 5.9 4.3 6.7 0.0 2.9 3 0 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding C1_3 PF07649.7 KFM01524.1 - 1.8 8.6 6.0 3.5 7.7 0.1 2.9 3 0 0 3 3 3 0 C1-like domain FYVE PF01363.16 KFM01524.1 - 2.6 7.9 6.0 42 4.1 4.1 2.5 1 1 0 1 1 1 0 FYVE zinc finger DUF1610 PF07754.6 KFM01524.1 - 3.7 7.7 13.2 5.6 7.1 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) TF_Zn_Ribbon PF08271.7 KFM01524.1 - 4.5 6.6 8.1 32 3.9 0.2 3.1 3 0 0 3 3 3 0 TFIIB zinc-binding Sgf11 PF08209.6 KFM01524.1 - 6.2 6.2 7.0 38 3.7 0.1 3.1 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) Histone PF00125.19 KFM01525.1 - 2.6e-26 91.5 0.1 3.2e-26 91.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFM01525.1 - 9.4e-07 28.8 0.7 1.5e-06 28.1 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KFM01525.1 - 0.0023 18.1 0.0 0.0033 17.6 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF2606 PF10794.4 KFM01525.1 - 0.062 12.7 0.1 0.084 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) E2F_TDP PF02319.15 KFM01526.1 - 5.3e-43 144.4 0.6 4.3e-21 74.2 0.0 2.7 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.14 KFM01526.1 - 0.00014 21.4 1.7 0.00075 19.1 0.0 2.7 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.7 KFM01526.1 - 0.0097 15.7 0.6 7.7 6.4 0.0 3.3 3 0 0 3 3 3 2 B-block binding subunit of TFIIIC LIM PF00412.17 KFM01527.1 - 1.4e-29 101.9 25.4 8.8e-17 60.9 3.1 2.1 2 0 0 2 2 2 2 LIM domain Zn_ribbon_2 PF12674.2 KFM01527.1 - 0.13 12.6 13.5 1 9.7 2.0 2.5 2 0 0 2 2 2 0 Putative zinc ribbon domain zf-TFIIB PF13453.1 KFM01527.1 - 0.3 10.3 9.0 1.3 8.2 0.0 3.5 3 0 0 3 3 3 0 Transcription factor zinc-finger zf-ribbon_3 PF13248.1 KFM01527.1 - 0.47 9.7 0.1 0.47 9.7 0.0 4.2 4 2 0 4 4 4 0 zinc-ribbon domain PHF5 PF03660.9 KFM01527.1 - 0.54 10.3 14.3 1.3 9.0 3.4 2.3 2 0 0 2 2 2 0 PHF5-like protein zinc_ribbon_2 PF13240.1 KFM01527.1 - 1 8.9 0.0 1 8.9 0.0 4.3 5 1 0 5 5 5 0 zinc-ribbon domain zf-FPG_IleRS PF06827.9 KFM01527.1 - 1.2 8.8 14.0 1.4 8.5 0.1 3.9 4 1 0 4 4 4 0 Zinc finger found in FPG and IleRS zf-C3HC4_2 PF13923.1 KFM01527.1 - 7.7 6.6 19.9 1.9 8.6 0.2 4.3 4 1 1 5 5 5 0 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.2 KFM01528.1 - 4.6e-41 139.0 0.1 5.8e-15 55.3 0.0 4.3 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFM01528.1 - 3.4e-40 133.8 0.3 7.1e-08 31.8 0.1 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 KFM01528.1 - 4.2e-33 112.6 1.1 5.3e-10 39.2 0.1 4.7 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFM01528.1 - 1.1e-31 108.6 1.0 1.2e-12 47.9 0.0 5.2 2 2 3 5 5 5 5 Ankyrin repeats (many copies) zf-DHHC PF01529.15 KFM01528.1 - 6.6e-31 107.0 11.4 6.6e-31 107.0 7.9 2.6 2 1 1 3 3 3 1 DHHC palmitoyltransferase Ank_3 PF13606.1 KFM01528.1 - 3.1e-28 94.9 0.1 2e-05 24.3 0.0 7.1 7 0 0 7 7 7 4 Ankyrin repeat zf-RanBP PF00641.13 KFM01528.1 - 0.091 11.8 2.1 0.26 10.4 1.5 1.7 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others DNA_pol3_delta2 PF13177.1 KFM01528.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit ERG4_ERG24 PF01222.12 KFM01529.1 - 1.2e-93 314.0 28.8 1.5e-93 313.7 19.9 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF912 PF06024.7 KFM01529.1 - 0.0055 16.7 0.0 0.021 14.8 0.0 1.9 2 0 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) ICMT PF04140.9 KFM01529.1 - 0.023 14.8 2.2 0.035 14.2 0.1 2.4 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1295 PF06966.7 KFM01529.1 - 0.32 10.2 10.3 0.011 15.0 2.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1295) NAD_synthase PF02540.12 KFM01530.1 - 1.3e-28 99.5 0.0 3.2e-28 98.2 0.0 1.6 1 1 0 1 1 1 1 NAD synthase CN_hydrolase PF00795.17 KFM01530.1 - 2.6e-25 88.8 0.0 4.8e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Asn_synthase PF00733.16 KFM01530.1 - 0.019 14.4 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase Cyclin_N PF00134.18 KFM01532.1 - 4.2e-36 123.3 2.6 4.2e-36 123.3 1.8 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFM01532.1 - 5.4e-22 77.9 2.8 1.5e-21 76.5 0.2 2.3 2 1 0 2 2 2 1 Cyclin, C-terminal domain Yae1_N PF09811.4 KFM01533.1 - 9e-10 37.9 5.3 1.5e-09 37.2 3.6 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal FGF PF00167.13 KFM01534.1 - 2.6e-32 111.1 0.0 3.2e-32 110.8 0.0 1.0 1 0 0 1 1 1 1 Fibroblast growth factor Peptidase_C25_C PF03785.9 KFM01534.1 - 0.15 11.9 0.0 14 5.5 0.0 2.2 2 0 0 2 2 2 0 Peptidase family C25, C terminal ig-like domain FGF PF00167.13 KFM01535.1 - 8e-34 116.0 0.1 9.5e-34 115.7 0.0 1.0 1 0 0 1 1 1 1 Fibroblast growth factor Anoctamin PF04547.7 KFM01536.1 - 2.5e-149 497.7 11.5 3.9e-149 497.1 8.0 1.3 1 0 0 1 1 1 1 Calcium-activated chloride channel Death PF00531.17 KFM01537.1 - 1.3e-18 66.4 0.1 8.6e-18 63.8 0.0 1.9 2 0 0 2 2 2 1 Death domain DED PF01335.16 KFM01537.1 - 4.7e-05 23.4 0.1 9.7e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 Death effector domain eIF-4B PF06273.6 KFM01537.1 - 0.028 13.2 0.2 0.029 13.1 0.1 1.0 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B HS1_rep PF02218.10 KFM01538.1 - 6e-114 371.6 68.9 2.7e-22 78.3 5.9 6.9 7 0 0 7 7 7 6 Repeat in HS1/Cortactin SH3_9 PF14604.1 KFM01538.1 - 8.7e-18 63.6 0.2 1.9e-17 62.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM01538.1 - 1.1e-16 59.9 0.2 2.8e-16 58.6 0.2 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFM01538.1 - 3e-10 39.4 0.0 8.3e-10 38.0 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain TMEM210 PF15195.1 KFM01538.1 - 2.8e-06 27.4 2.0 16 5.6 0.0 5.8 1 1 5 6 6 6 1 TMEM210 family AMP-binding_C_2 PF14535.1 KFM01538.1 - 0.027 14.4 3.3 0.27 11.3 0.7 3.1 2 1 0 2 2 2 0 AMP-binding enzyme C-terminal domain DUF4551 PF15087.1 KFM01538.1 - 0.55 8.5 10.2 0.78 8.0 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) PV-1 PF06637.6 KFM01538.1 - 1.3 7.5 8.6 2 6.9 5.9 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Endonuc-dimeris PF09124.5 KFM01538.1 - 3.5 7.3 9.4 17 5.0 0.3 3.7 3 0 0 3 3 3 0 T4 recombination endonuclease VII, dimerisation SAM_1 PF00536.25 KFM01539.1 - 1.1e-19 70.2 0.1 2.1e-19 69.4 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFM01539.1 - 4.2e-18 64.9 0.2 8.1e-18 64.0 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDZ PF00595.19 KFM01539.1 - 1.1e-08 35.1 0.0 4.1e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) SAM_PNT PF02198.11 KFM01539.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Actin PF00022.14 KFM01541.1 - 1e-161 537.7 0.0 1.2e-161 537.5 0.0 1.0 1 0 0 1 1 1 1 Actin UPAR_LY6 PF00021.16 KFM01542.1 - 3e-05 24.3 15.6 5.3e-05 23.5 10.8 1.4 1 0 0 1 1 1 1 u-PAR/Ly-6 domain Activin_recp PF01064.18 KFM01542.1 - 1.2 9.7 17.7 2.5 8.8 12.3 1.5 1 1 0 1 1 1 0 Activin types I and II receptor domain DUF525 PF04379.9 KFM01543.1 - 3.3e-28 97.4 0.1 9.9e-28 95.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF525) SMI1_KNR4 PF09346.5 KFM01543.1 - 2e-06 27.8 0.0 5.3e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) LIM PF00412.17 KFM01544.1 - 1.9e-28 98.3 21.3 1.6e-15 56.9 6.3 2.0 2 0 0 2 2 2 2 LIM domain C1_4 PF07975.7 KFM01544.1 - 0.012 15.5 5.7 0.012 15.5 4.0 2.9 2 1 0 2 2 2 0 TFIIH C1-like domain Vps39_2 PF10367.4 KFM01544.1 - 0.055 13.6 0.8 0.055 13.6 0.6 3.3 1 1 2 4 4 4 0 Vacuolar sorting protein 39 domain 2 Churchill PF06573.6 KFM01544.1 - 0.57 10.1 10.1 0.18 11.7 1.6 2.2 1 1 1 2 2 2 0 Churchill protein DiS_P_DiS PF06750.8 KFM01544.1 - 0.98 9.2 5.5 11 5.9 2.5 2.8 2 1 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain DUF1140 PF06600.6 KFM01545.1 - 0.067 13.3 1.6 0.25 11.4 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1140) GrpE PF01025.14 KFM01545.1 - 0.088 12.3 5.9 0.11 12.0 4.1 1.3 1 0 0 1 1 1 0 GrpE DUF3608 PF12257.3 KFM01545.1 - 0.088 11.6 0.4 0.11 11.4 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3608) OmpH PF03938.9 KFM01545.1 - 0.94 9.4 8.0 1.6 8.6 5.6 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) GNAT_acetyltr_2 PF13718.1 KFM01546.1 - 2.6e-82 274.8 0.0 6.8e-82 273.5 0.0 1.7 2 0 0 2 2 2 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 KFM01546.1 - 6.7e-66 221.2 0.0 2.1e-65 219.6 0.0 1.9 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.6 KFM01546.1 - 1.1e-43 146.8 0.2 3.1e-43 145.3 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 KFM01546.1 - 7.7e-33 112.6 1.1 7.7e-33 112.6 0.8 2.2 2 0 0 2 2 2 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 KFM01546.1 - 8e-06 25.9 0.0 9e-05 22.5 0.0 2.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFM01546.1 - 0.00043 20.2 0.1 0.0021 18.0 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Focal_AT PF03623.8 KFM01546.1 - 0.017 14.6 1.6 0.055 12.9 1.1 1.9 1 0 0 1 1 1 0 Focal adhesion targeting region Ank_2 PF12796.2 KFM01547.1 - 8.4e-34 115.7 5.0 5.9e-18 64.9 0.1 3.6 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFM01547.1 - 2.1e-24 84.0 5.1 2.3e-08 33.4 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat BTB PF00651.26 KFM01547.1 - 9.4e-24 83.5 0.7 2.5e-23 82.1 0.4 1.8 1 1 0 1 1 1 1 BTB/POZ domain Ank_4 PF13637.1 KFM01547.1 - 9.6e-18 64.2 0.2 1.6e-05 25.2 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM01547.1 - 1.1e-17 62.3 1.2 9e-05 22.3 0.0 5.6 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 KFM01547.1 - 2.1e-13 50.0 3.3 0.00037 20.6 0.0 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) BACK PF07707.10 KFM01547.1 - 0.00047 19.9 0.2 0.0026 17.5 0.1 2.3 2 0 0 2 2 2 1 BTB And C-terminal Kelch Histone PF00125.19 KFM01547.1 - 0.46 10.6 4.2 38 4.5 0.1 3.7 3 0 0 3 3 3 0 Core histone H2A/H2B/H3/H4 Catalase PF00199.14 KFM01548.1 - 1.3e-189 629.7 0.0 1.8e-189 629.3 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KFM01548.1 - 1.5e-19 69.6 1.8 4.1e-19 68.1 0.3 2.4 3 0 0 3 3 3 1 Catalase-related immune-responsive FA_desaturase PF00487.19 KFM01549.1 - 1.1e-35 123.3 24.9 1.1e-35 123.3 17.3 1.4 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KFM01551.1 - 1.4e-18 66.4 0.1 2.4e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 KFM01551.1 - 2.3e-14 53.4 3.6 2.3e-14 53.4 2.5 2.0 1 1 1 2 2 2 1 Fatty acid desaturase CHGN PF05679.11 KFM01553.1 - 1.7e-165 551.5 0.0 1.9e-165 551.4 0.0 1.0 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.9 KFM01553.1 - 1.2e-12 47.1 0.0 2.8e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFM01553.1 - 8.6e-11 41.4 0.0 1.8e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF1649 PF07855.7 KFM01553.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1649) CHGN PF05679.11 KFM01554.1 - 1.4e-12 47.1 0.3 1.7e-12 46.8 0.2 1.1 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.11 KFM01554.1 - 4e-06 26.2 0.0 4.8e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Fringe-like UPF0258 PF06789.7 KFM01555.1 - 6.2e-29 101.1 0.0 8.4e-29 100.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0258) Chordopox_A33R PF05966.7 KFM01555.1 - 0.034 12.9 0.1 0.04 12.6 0.1 1.2 1 0 0 1 1 1 0 Chordopoxvirus A33R protein DUF3377 PF11857.3 KFM01555.1 - 0.078 12.6 0.4 0.14 11.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) INCENP_ARK-bind PF03941.10 KFM01555.1 - 0.17 11.7 1.4 0.28 11.0 1.0 1.3 1 0 0 1 1 1 0 Inner centromere protein, ARK binding region Herpes_US9 PF06072.6 KFM01555.1 - 0.32 10.8 1.3 0.45 10.3 0.9 1.2 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 ADAM_spacer1 PF05986.9 KFM01556.1 - 1.1e-29 102.6 0.0 2.4e-29 101.5 0.0 1.6 1 0 0 1 1 1 1 ADAM-TS Spacer 1 TSP_1 PF00090.14 KFM01556.1 - 1.9e-23 82.2 98.2 5.9e-09 35.9 7.7 7.8 8 1 0 8 8 8 5 Thrombospondin type 1 domain Reprolysin PF01421.14 KFM01556.1 - 7.5e-23 81.1 1.8 7.5e-23 81.1 1.2 3.6 3 1 0 3 3 3 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.14 KFM01556.1 - 2.8e-21 75.6 0.0 5.7e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_5 PF13688.1 KFM01556.1 - 9.4e-13 48.5 0.6 2.8e-12 46.9 0.4 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12 PLAC PF08686.6 KFM01556.1 - 6.3e-10 39.1 9.2 6.7e-09 35.8 6.4 3.0 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain Reprolysin_4 PF13583.1 KFM01556.1 - 9.4e-10 38.3 0.1 3e-09 36.7 0.1 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KFM01556.1 - 1e-09 38.9 0.1 2.6e-09 37.6 0.0 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFM01556.1 - 7.8e-08 32.5 0.9 1.8e-07 31.3 0.2 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KFM01556.1 - 0.00032 20.4 0.4 0.00058 19.6 0.3 1.3 1 0 0 1 1 1 1 Matrixin Isochorismatase PF00857.15 KFM01557.1 - 2.3e-26 92.7 0.0 3.5e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family AMP-binding_C PF13193.1 KFM01557.1 - 0.15 12.9 0.4 0.27 12.2 0.3 1.7 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 KFM01558.1 - 5.9e-74 248.9 0.0 7.9e-74 248.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFM01558.1 - 2.2e-08 34.9 0.0 4.1e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 KFM01559.1 - 7.2e-75 251.9 0.0 1.2e-74 251.2 0.0 1.3 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFM01559.1 - 1e-08 35.9 0.0 3.7e-08 34.1 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ldh_1_C PF02866.13 KFM01560.1 - 2.3e-51 173.9 0.0 3.3e-51 173.4 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 KFM01560.1 - 2.2e-48 163.6 0.0 3.2e-48 163.1 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 KFM01560.1 - 0.00036 20.8 0.0 0.0021 18.3 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KFM01560.1 - 0.00085 18.0 0.0 0.0012 17.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KFM01560.1 - 0.0027 17.7 0.0 0.0059 16.6 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 KFM01560.1 - 0.011 15.6 0.0 0.031 14.2 0.0 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus THF_DHG_CYH_C PF02882.14 KFM01560.1 - 0.018 14.0 0.0 0.14 11.2 0.0 2.3 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DSPc PF00782.15 KFM01561.1 - 5e-21 74.6 0.0 7.5e-21 74.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.15 KFM01561.1 - 0.0043 17.3 0.1 0.12 12.7 0.1 2.3 1 1 0 1 1 1 1 Rhodanese-like domain TMPIT PF07851.8 KFM01562.1 - 6.7e-160 531.5 18.5 7.9e-160 531.3 12.8 1.0 1 0 0 1 1 1 1 TMPIT-like protein ALIX_LYPXL_bnd PF13949.1 KFM01562.1 - 0.054 12.4 5.1 0.075 11.9 3.5 1.1 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV IFT57 PF10498.4 KFM01562.1 - 0.18 10.5 5.0 0.24 10.1 3.5 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Atg14 PF10186.4 KFM01562.1 - 0.65 8.8 4.9 0.91 8.4 3.4 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FAD_binding_1 PF00667.15 KFM01563.1 - 5e-83 277.8 0.0 7.5e-83 277.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KFM01563.1 - 2.4e-38 131.3 0.3 2.4e-38 131.3 0.2 2.0 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 KFM01563.1 - 4.8e-10 39.9 1.8 0.00044 20.7 0.0 3.5 3 0 0 3 3 3 2 Oxidoreductase NAD-binding domain DUF3755 PF12579.3 KFM01563.1 - 0.06 12.7 0.0 0.15 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3755) Rhomboid PF01694.17 KFM01564.1 - 2.4e-13 50.3 7.8 3.1e-13 49.9 5.4 1.1 1 0 0 1 1 1 1 Rhomboid family DER1 PF04511.10 KFM01564.1 - 0.0028 17.1 1.4 0.0095 15.4 1.0 1.9 1 1 0 1 1 1 1 Der1-like family ABC2_membrane_3 PF12698.2 KFM01564.1 - 5.9 5.8 7.5 8.8 5.2 5.2 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein RRM_1 PF00076.17 KFM01565.1 - 3.1e-13 49.1 0.1 1.6e-12 46.8 0.1 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.13 KFM01565.1 - 2.2e-08 33.0 5.5 3.3e-08 32.4 3.8 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_6 PF14259.1 KFM01565.1 - 2.7e-08 33.6 0.0 4.7e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM01565.1 - 0.00063 19.5 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GAS2 PF02187.12 KFM01566.1 - 1.7e-36 123.8 0.3 2.7e-36 123.1 0.2 1.3 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.26 KFM01566.1 - 1.2e-09 38.1 0.1 2.9e-09 36.9 0.0 1.7 1 1 0 1 1 1 1 Calponin homology (CH) domain Ras PF00071.17 KFM01567.1 - 4e-25 88.0 0.0 7.8e-25 87.1 0.0 1.4 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KFM01567.1 - 9.8e-15 55.0 0.0 2.1e-14 54.0 0.0 1.5 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM01567.1 - 0.00051 19.3 0.0 0.0082 15.3 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFM01567.1 - 0.0048 16.8 0.0 0.0068 16.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.1 KFM01567.1 - 0.0052 16.7 0.0 0.0091 15.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KFM01567.1 - 0.069 13.0 0.0 0.17 11.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KFM01567.1 - 0.091 12.7 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.18 KFM01567.1 - 0.12 12.1 0.1 0.26 11.1 0.0 1.9 1 1 0 1 1 1 0 Dynamin family Adaptin_N PF01602.15 KFM01568.1 - 9.9e-168 558.7 14.7 1.3e-167 558.3 10.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region B2-adapt-app_C PF09066.5 KFM01568.1 - 9.3e-38 128.6 0.2 2.5e-37 127.2 0.1 1.9 2 0 0 2 2 1 1 Beta2-adaptin appendage, C-terminal sub-domain Cnd1 PF12717.2 KFM01568.1 - 1.7e-37 128.9 7.5 1.9e-35 122.3 0.4 4.2 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KFM01568.1 - 2e-23 82.4 5.1 1.1e-06 28.7 0.0 5.8 2 1 5 7 7 7 5 HEAT repeats HEAT PF02985.17 KFM01568.1 - 5.8e-13 47.7 7.7 0.0038 17.1 0.0 7.0 7 0 0 7 7 7 4 HEAT repeat Alpha_adaptinC2 PF02883.15 KFM01568.1 - 2.1e-11 44.1 0.3 5.2e-11 42.8 0.2 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Arm PF00514.18 KFM01568.1 - 6e-08 32.2 3.1 0.0045 16.7 0.0 5.1 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 KFM01568.1 - 0.00059 20.2 9.6 1.3 9.6 0.0 6.6 6 3 3 9 9 9 2 HEAT-like repeat CLASP_N PF12348.3 KFM01568.1 - 0.0012 18.2 2.1 0.86 8.9 0.1 4.4 2 2 1 3 3 3 1 CLASP N terminal Cnd3 PF12719.2 KFM01568.1 - 0.0013 17.8 3.4 0.0073 15.3 0.2 2.6 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain Atx10homo_assoc PF09759.4 KFM01568.1 - 0.0089 15.7 0.0 1.4 8.6 0.0 3.1 2 1 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain MOR2-PAG1_C PF14225.1 KFM01568.1 - 0.016 14.9 3.0 1 9.0 0.0 3.1 2 1 1 3 3 3 0 Cell morphogenesis C-terminal Pex2_Pex12 PF04757.9 KFM01569.1 - 5.1e-53 179.8 3.7 6.6e-53 179.4 2.6 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 KFM01569.1 - 3.5e-06 26.9 3.1 6.2e-06 26.1 2.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM01569.1 - 0.00081 19.0 2.0 0.0015 18.1 1.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM01569.1 - 0.0045 16.8 6.5 0.049 13.4 4.7 2.2 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KFM01569.1 - 0.014 14.9 1.7 0.027 14.1 1.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PAS_5 PF07310.8 KFM01569.1 - 0.03 13.8 0.1 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 PAS domain zf-RING_5 PF14634.1 KFM01569.1 - 0.098 12.3 0.8 5.5 6.7 0.1 2.3 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFM01569.1 - 0.17 11.8 2.5 0.38 10.6 1.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KFM01569.1 - 0.26 11.4 3.3 2.8 8.1 2.3 2.3 1 1 1 2 2 2 0 RING-H2 zinc finger AAA_4 PF04326.9 KFM01570.1 - 1.6e-17 63.7 0.0 6.9e-13 48.8 0.0 2.6 2 0 0 2 2 2 2 Divergent AAA domain DUF2075 PF09848.4 KFM01570.1 - 1.2e-06 27.7 0.0 2.4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.1 KFM01570.1 - 0.0001 22.2 0.1 0.00027 20.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KFM01570.1 - 0.00046 19.8 0.0 0.0015 18.2 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KFM01570.1 - 0.0013 18.8 0.3 0.068 13.3 0.2 2.7 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KFM01570.1 - 0.0059 15.4 0.0 0.035 12.9 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.24 KFM01570.1 - 0.0077 16.4 0.0 0.017 15.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 KFM01570.1 - 0.0077 15.7 0.1 0.4 10.1 0.0 2.4 1 1 1 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 KFM01570.1 - 0.01 15.6 0.1 0.028 14.2 0.1 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_11 PF13086.1 KFM01570.1 - 0.014 14.9 1.4 0.06 12.9 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_25 PF13481.1 KFM01570.1 - 0.015 14.6 0.1 0.19 11.1 0.1 2.2 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KFM01570.1 - 0.017 15.3 0.0 0.044 13.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.11 KFM01570.1 - 0.028 13.6 1.2 3.5 6.7 0.1 2.4 1 1 1 2 2 2 0 PhoH-like protein AAA_24 PF13479.1 KFM01570.1 - 0.15 11.6 0.4 0.29 10.7 0.3 1.4 1 0 0 1 1 1 0 AAA domain UNC45-central PF11701.3 KFM01571.1 - 2.3e-49 167.0 11.2 3.8e-47 159.8 0.7 4.1 3 0 0 3 3 3 2 Myosin-binding striated muscle assembly central TPR_11 PF13414.1 KFM01571.1 - 1.6e-22 78.9 18.6 2.6e-15 55.8 4.3 2.6 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KFM01571.1 - 3.6e-13 48.5 10.6 5e-05 22.7 0.4 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat HEAT_2 PF13646.1 KFM01571.1 - 2.2e-12 47.0 2.5 0.0024 18.0 0.0 5.6 3 2 3 6 6 6 3 HEAT repeats TPR_2 PF07719.12 KFM01571.1 - 5.9e-12 44.5 9.2 0.0012 18.5 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat Arm PF00514.18 KFM01571.1 - 2.6e-06 27.0 10.6 0.063 13.1 0.1 6.5 7 0 0 7 7 6 2 Armadillo/beta-catenin-like repeat TPR_8 PF13181.1 KFM01571.1 - 1.6e-05 24.3 11.2 0.017 14.8 0.1 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFM01571.1 - 4.6e-05 23.2 7.3 0.0017 18.2 2.4 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFM01571.1 - 0.00041 20.1 1.4 0.011 15.5 0.3 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFM01571.1 - 0.00046 20.7 7.5 0.0066 17.0 2.1 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFM01571.1 - 0.00059 19.8 3.1 0.84 9.9 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFM01571.1 - 0.018 15.6 1.1 4.8 8.1 0.1 3.7 3 1 0 3 3 2 0 Tetratricopeptide repeat Apc3 PF12895.2 KFM01571.1 - 0.023 14.8 9.9 0.02 15.0 4.9 2.5 2 0 0 2 2 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KFM01571.1 - 0.081 12.7 1.6 0.26 11.1 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat PurS PF02700.9 KFM01571.1 - 0.12 12.3 1.8 1.7 8.6 0.1 3.0 3 0 0 3 3 3 0 Phosphoribosylformylglycinamidine (FGAM) synthase TPR_6 PF13174.1 KFM01571.1 - 1 9.9 7.5 7.4 7.2 0.1 3.7 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFM01571.1 - 3.3 8.1 8.6 5 7.5 1.5 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat GED PF02212.13 KFM01571.1 - 3.6 7.5 7.6 4.7 7.1 0.6 3.5 3 0 0 3 3 3 0 Dynamin GTPase effector domain zf-C3HC4_3 PF13920.1 KFM01572.1 - 1e-12 47.4 11.8 1e-12 47.4 8.2 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Armet PF10208.4 KFM01572.1 - 3.1e-07 30.1 0.5 0.021 14.4 0.0 2.5 2 0 0 2 2 2 2 Degradation arginine-rich protein for mis-folding zf-C3HC4_2 PF13923.1 KFM01572.1 - 4.4e-05 23.4 14.8 4.4e-05 23.4 10.3 3.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.11 KFM01572.1 - 0.00016 21.5 6.0 0.00016 21.5 4.1 2.6 2 1 0 2 2 2 1 FYVE-type zinc finger SAP PF02037.22 KFM01572.1 - 0.00076 18.9 0.6 0.5 9.9 0.1 2.9 3 0 0 3 3 3 2 SAP domain zf-RING_5 PF14634.1 KFM01572.1 - 0.0019 17.8 12.1 0.0019 17.8 8.4 2.6 2 0 0 2 2 2 1 zinc-RING finger domain FYVE PF01363.16 KFM01572.1 - 0.0022 17.8 14.2 0.0022 17.8 9.9 3.8 3 2 0 3 3 3 1 FYVE zinc finger Siva PF05458.7 KFM01572.1 - 0.0094 15.5 2.4 0.0094 15.5 1.7 2.3 2 0 0 2 2 2 1 Cd27 binding protein (Siva) Prok-RING_4 PF14447.1 KFM01572.1 - 0.018 14.5 6.9 0.018 14.5 4.8 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 IBR PF01485.16 KFM01572.1 - 0.53 10.1 18.5 0.24 11.2 3.8 2.8 2 0 0 2 2 2 0 IBR domain Rep_fac-A_C PF08646.5 KFM01574.1 - 1.6e-54 183.5 9.9 5.9e-50 168.7 5.3 2.5 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 KFM01574.1 - 1.6e-26 92.0 0.1 3.2e-26 91.0 0.1 1.5 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 KFM01574.1 - 5.7e-13 48.5 0.3 1.1e-11 44.4 0.0 2.9 2 1 1 3 3 3 1 OB-fold nucleic acid binding domain SET PF00856.23 KFM01575.1 - 3.6e-16 59.8 0.0 7.9e-16 58.7 0.0 1.6 1 1 0 1 1 1 1 SET domain TPR_12 PF13424.1 KFM01575.1 - 4.3e-10 39.3 0.6 3e-05 23.8 0.1 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFM01575.1 - 8e-08 31.6 4.1 0.0067 16.2 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFM01575.1 - 1.8e-07 30.7 2.2 0.0053 16.3 0.2 4.4 3 1 0 4 4 4 2 TPR repeat Apc3 PF12895.2 KFM01575.1 - 7.5e-07 29.1 4.1 0.016 15.2 0.1 3.6 4 0 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 zf-MYND PF01753.13 KFM01575.1 - 1.2e-06 28.2 14.0 1.2e-06 28.2 9.7 3.4 3 0 0 3 3 3 1 MYND finger TPR_10 PF13374.1 KFM01575.1 - 2.9e-05 23.8 0.1 0.00046 20.0 0.0 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFM01575.1 - 9.5e-05 21.8 0.4 0.081 12.5 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFM01575.1 - 0.0002 21.7 1.1 0.19 12.4 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFM01575.1 - 0.00022 21.8 2.3 0.3 11.8 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFM01575.1 - 0.0012 18.5 2.8 0.0029 17.2 0.0 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.9 KFM01575.1 - 0.0014 18.8 5.4 0.16 12.4 0.6 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFM01575.1 - 0.059 13.1 0.0 0.45 10.4 0.0 2.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3856 PF12968.2 KFM01575.1 - 0.12 12.1 0.5 1.5 8.6 0.1 2.8 3 1 0 3 3 2 0 Domain of Unknown Function (DUF3856) TPR_19 PF14559.1 KFM01575.1 - 0.19 12.1 4.5 4.2 7.7 0.1 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat Serpin PF00079.15 KFM01576.1 - 2.1e-85 287.1 0.1 2.4e-85 286.9 0.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.15 KFM01577.1 - 6.3e-87 292.1 1.4 7.3e-87 291.9 1.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) WD40 PF00400.27 KFM01578.1 - 9e-17 60.2 10.6 4.4e-08 32.6 0.1 6.1 6 1 0 6 6 6 4 WD domain, G-beta repeat PQQ_2 PF13360.1 KFM01578.1 - 0.00097 18.6 0.0 0.0087 15.5 0.0 2.2 1 1 1 2 2 2 1 PQQ-like domain Nup160 PF11715.3 KFM01578.1 - 0.0071 14.5 0.0 0.019 13.1 0.0 1.7 1 0 0 1 1 1 1 Nucleoporin Nup120/160 PROCN PF08083.6 KFM01579.1 - 4.9e-224 743.2 6.7 8.6e-224 742.4 4.7 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 KFM01579.1 - 2.7e-129 429.3 0.7 4.7e-129 428.5 0.5 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 KFM01579.1 - 5.7e-94 311.8 2.2 1.1e-93 310.9 1.5 1.5 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 KFM01579.1 - 1.8e-81 271.1 3.3 1.8e-81 271.1 2.3 2.0 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 KFM01579.1 - 2.5e-70 234.3 0.0 5.7e-70 233.1 0.0 1.7 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 KFM01579.1 - 4.4e-52 175.0 0.0 9.9e-52 173.9 0.0 1.7 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.4 KFM01579.1 - 8.4e-46 153.7 0.6 2.1e-45 152.4 0.4 1.7 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.16 KFM01579.1 - 6.3e-14 51.6 0.0 3.3e-13 49.3 0.0 2.2 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RILP PF11461.3 KFM01581.1 - 4.6e-18 65.1 6.0 4.6e-18 65.1 4.2 2.7 3 1 0 3 3 3 1 Rab interacting lysosomal protein YflT PF11181.3 KFM01581.1 - 0.054 13.6 3.7 0.075 13.1 0.7 2.3 2 0 0 2 2 2 0 Heat induced stress protein YflT DUF72 PF01904.13 KFM01581.1 - 0.06 13.0 2.2 0.086 12.5 0.9 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF72 DIRP PF06584.8 KFM01581.1 - 0.063 13.1 0.4 0.063 13.1 0.3 2.4 2 1 1 3 3 3 0 DIRP Adeno_E4_34 PF04528.8 KFM01581.1 - 0.42 10.1 2.5 1.2 8.6 1.8 1.8 1 0 0 1 1 1 0 Adenovirus early E4 34 kDa protein conserved region NPV_P10 PF05531.7 KFM01581.1 - 0.44 10.8 3.2 2.3 8.5 0.7 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ATG16 PF08614.6 KFM01581.1 - 1.3 8.8 26.4 2.7 7.7 0.7 3.0 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Arteri_nucleo PF01481.11 KFM01581.1 - 2.4 8.2 5.8 2 8.5 0.2 2.9 1 1 2 3 3 3 0 Arterivirus nucleocapsid protein Takusan PF04822.8 KFM01581.1 - 5.8 6.7 12.7 0.25 11.1 0.7 2.8 2 1 1 3 3 3 0 Takusan DUF3584 PF12128.3 KFM01581.1 - 6 4.0 24.4 0.24 8.7 6.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) MFS_1 PF07690.11 KFM01582.1 - 3.2e-14 52.4 20.7 3.2e-14 52.4 14.4 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3169 PF11368.3 KFM01582.1 - 0.032 13.4 0.2 0.1 11.7 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Adeno_E3_CR2 PF02439.10 KFM01582.1 - 0.057 12.9 0.1 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 IP_trans PF02121.13 KFM01583.1 - 1.9e-136 453.2 2.7 2.3e-136 452.9 1.8 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Exo_endo_phos PF03372.18 KFM01584.1 - 9.2e-24 84.7 0.1 1.3e-23 84.2 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CALCOCO1 PF07888.6 KFM01584.1 - 6.3e-10 37.9 0.3 9.6e-10 37.3 0.2 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Myosin_head PF00063.16 KFM01585.1 - 3.9e-238 791.9 4.4 7.5e-238 791.0 3.1 1.4 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 KFM01585.1 - 5.5e-39 133.5 2.4 9.4e-39 132.7 1.7 1.4 1 0 0 1 1 1 1 Myosin tail IQ PF00612.22 KFM01585.1 - 7.4e-05 22.0 14.5 0.0032 16.9 0.7 3.8 4 0 0 4 4 4 2 IQ calmodulin-binding motif AAA_22 PF13401.1 KFM01585.1 - 0.00088 19.4 0.2 0.015 15.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 KFM01585.1 - 0.0083 15.2 0.0 0.02 13.9 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 KFM01585.1 - 0.039 14.7 0.0 0.16 12.7 0.0 2.2 1 0 0 1 1 1 0 AAA domain 14-3-3 PF00244.15 KFM01586.1 - 5.2e-108 359.5 0.4 5.8e-108 359.4 0.2 1.0 1 0 0 1 1 1 1 14-3-3 protein SH3_2 PF07653.12 KFM01587.1 - 6.3e-25 86.4 0.4 4.3e-12 45.3 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KFM01587.1 - 7.7e-19 66.8 0.4 3.2e-15 55.2 0.2 2.3 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 KFM01587.1 - 1.1e-14 53.6 0.1 8.2e-11 41.3 0.1 2.3 2 0 0 2 2 2 2 Variant SH3 domain DUF2414 PF10309.4 KFM01588.1 - 3.9e-23 80.9 0.0 9.2e-23 79.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) RNA_bind PF08675.6 KFM01588.1 - 2.2e-05 24.3 0.0 5.2e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 RNA binding domain T2SK PF03934.8 KFM01589.1 - 0.00041 19.6 0.3 0.0021 17.3 0.0 1.9 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein K LRR_4 PF12799.2 KFM01589.1 - 0.0019 17.7 0.8 0.0089 15.6 0.3 2.2 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KFM01589.1 - 0.0035 17.2 0.3 0.19 11.8 0.1 3.1 2 0 0 2 2 2 1 Leucine Rich repeat LRR_1 PF00560.28 KFM01589.1 - 0.012 15.5 0.9 1.4 9.2 0.1 3.3 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_7 PF13504.1 KFM01589.1 - 0.041 14.0 0.3 0.27 11.5 0.2 2.5 1 0 0 1 1 1 0 Leucine rich repeat UCH PF00443.24 KFM01589.1 - 0.054 12.6 0.0 0.066 12.3 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase TMEM219 PF14940.1 KFM01590.1 - 4.6e-96 320.2 1.4 5.7e-96 319.9 1.0 1.1 1 0 0 1 1 1 1 Transmembrane 219 VPS9 PF02204.13 KFM01591.1 - 2.4e-30 104.6 0.0 7.4e-30 103.0 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain zf-A20 PF01754.11 KFM01591.1 - 4.7e-12 45.2 5.3 9.6e-12 44.2 3.7 1.6 1 0 0 1 1 1 1 A20-like zinc finger DUF501 PF04417.7 KFM01591.1 - 0.036 13.9 4.0 1.7 8.4 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF501) BTB_2 PF02214.17 KFM01592.1 - 1.4e-19 70.0 0.0 8.6e-19 67.5 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Sulfotransfer_3 PF13469.1 KFM01593.1 - 2.4e-14 54.5 0.1 3.6e-14 53.9 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 KFM01593.1 - 1.8e-08 34.0 0.1 1.6e-07 30.8 0.0 2.3 1 1 0 1 1 1 1 Sulfotransferase domain RNA_pol_Rpb4 PF03874.11 KFM01594.1 - 2.6e-09 37.1 0.5 2.8e-09 37.0 0.3 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb4 Glyco_hydro_2_C PF02836.12 KFM01595.1 - 1.7e-99 332.4 0.0 2.1e-99 332.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.13 KFM01595.1 - 6.3e-32 110.4 0.0 1.1e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 KFM01595.1 - 4.5e-07 30.2 0.5 2.4e-06 27.9 0.3 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 2 Cellulase-like PF12876.2 KFM01595.1 - 0.00072 19.9 0.0 0.0019 18.6 0.0 1.8 1 0 0 1 1 1 1 Sugar-binding cellulase-like VKOR PF07884.9 KFM01596.1 - 5.3e-21 74.9 10.2 5.9e-21 74.7 7.1 1.0 1 0 0 1 1 1 1 Vitamin K epoxide reductase family Claudin_2 PF13903.1 KFM01596.1 - 0.051 13.2 5.0 0.057 13.0 3.5 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF2207 PF09972.4 KFM01596.1 - 4 5.9 6.5 4.4 5.7 4.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Yip1 PF04893.12 KFM01596.1 - 4.2 6.8 13.7 7.4 6.0 9.5 1.5 1 1 0 1 1 1 0 Yip1 domain SPC25 PF06703.6 KFM01596.1 - 4.5 6.8 9.7 8.6 5.9 6.7 1.5 1 1 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) CHCH PF06747.8 KFM01597.1 - 4.4e-07 29.6 7.9 7.5e-07 28.9 5.5 1.4 1 0 0 1 1 1 1 CHCH domain DUF2076 PF09849.4 KFM01597.1 - 0.078 13.0 21.0 0.26 11.2 14.6 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Med3 PF11593.3 KFM01597.1 - 2.1 7.4 11.6 2.6 7.1 8.0 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Pkinase PF00069.20 KFM01598.1 - 2.7e-76 256.1 0.0 3.4e-76 255.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM01598.1 - 6.4e-33 113.9 0.0 8e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM01598.1 - 1.6e-09 37.1 0.0 1.5e-07 30.6 0.0 2.1 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.9 KFM01598.1 - 4.5e-06 25.8 0.1 7.5e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFM01598.1 - 6e-05 22.4 0.2 0.00014 21.2 0.2 1.6 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KFM01598.1 - 6.6e-05 22.7 0.1 0.22 11.1 0.1 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFM01598.1 - 0.0061 16.1 0.2 0.0094 15.5 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 KFM01598.1 - 0.007 15.7 0.1 0.015 14.6 0.1 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL FGE-sulfatase PF03781.11 KFM01599.1 - 3.6e-82 275.6 3.1 4.1e-82 275.4 2.1 1.0 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 HAD PF12710.2 KFM01600.1 - 3.2e-17 63.3 0.0 7.1e-17 62.1 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFM01600.1 - 3.7e-13 50.3 0.3 5.8e-12 46.4 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 KFM01600.1 - 1.2e-05 24.7 0.0 2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Put_Phosphatase PF06888.7 KFM01600.1 - 2.4e-05 23.6 0.0 7.6e-05 21.9 0.0 1.7 2 1 0 2 2 2 1 Putative Phosphatase HAD_2 PF13419.1 KFM01600.1 - 3.2e-05 24.2 0.0 6.2e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 KFM01600.1 - 0.0034 16.8 0.0 0.2 10.9 0.0 2.1 2 0 0 2 2 2 1 HAD superfamily, subfamily IIIB (Acid phosphatase) Hydrolase_like PF13242.1 KFM01600.1 - 0.0076 15.9 0.0 0.022 14.4 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_3 PF08282.7 KFM01600.1 - 0.013 15.0 0.1 0.63 9.5 0.0 2.4 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase PFK PF00365.15 KFM01600.1 - 0.062 12.2 0.0 0.095 11.6 0.0 1.2 1 0 0 1 1 1 0 Phosphofructokinase StbA PF06406.6 KFM01600.1 - 0.066 12.1 0.0 0.34 9.7 0.0 1.9 2 0 0 2 2 2 0 StbA protein NIPSNAP PF07978.8 KFM01601.1 - 1.1e-37 128.1 0.7 1.3e-31 108.5 0.1 2.2 2 0 0 2 2 2 2 NIPSNAP Ribosomal_S17 PF00366.15 KFM01602.1 - 2.5e-09 37.0 0.3 8.8e-09 35.2 0.1 1.8 1 1 1 2 2 2 1 Ribosomal protein S17 FERM_C PF09380.5 KFM01603.1 - 1.7e-34 117.9 0.6 1.7e-34 117.9 0.4 2.5 3 0 0 3 3 3 1 FERM C-terminal PH-like domain ERM PF00769.14 KFM01603.1 - 1e-32 113.6 41.2 1e-32 113.6 28.5 2.1 2 0 0 2 2 2 1 Ezrin/radixin/moesin family FERM_M PF00373.13 KFM01603.1 - 3e-24 85.5 1.7 3e-24 85.5 1.2 2.8 2 1 0 2 2 2 1 FERM central domain FERM_N PF09379.5 KFM01603.1 - 4.1e-14 52.3 1.2 4.2e-13 49.1 0.1 3.1 3 0 0 3 3 3 1 FERM N-terminal domain DUF4613 PF15390.1 KFM01603.1 - 5.6 5.0 14.0 7.7 4.5 9.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) IL8 PF00048.15 KFM01604.1 - 2.3e-07 30.6 0.2 2.9e-07 30.3 0.1 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like MGC-24 PF05283.6 KFM01605.1 - 9.8e-07 28.7 14.7 1.2e-06 28.4 10.2 1.1 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24) BIR PF00653.16 KFM01606.1 - 4.4e-67 222.4 16.3 2.1e-23 82.5 0.4 3.8 4 0 0 4 4 4 3 Inhibitor of Apoptosis domain CARD PF00619.16 KFM01606.1 - 5.7e-22 77.3 0.3 1.2e-21 76.3 0.2 1.5 1 0 0 1 1 1 1 Caspase recruitment domain zf-C3HC4_3 PF13920.1 KFM01606.1 - 7.9e-15 54.2 8.5 7.9e-15 54.2 5.9 2.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM01606.1 - 5.1e-06 26.4 12.1 5.1e-06 26.4 8.4 3.0 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 KFM01606.1 - 0.0018 17.7 3.7 0.0051 16.3 2.5 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.1 KFM01606.1 - 0.0026 17.4 8.7 0.0026 17.4 6.0 2.3 2 0 0 2 2 2 1 zinc-RING finger domain DUF2039 PF10217.4 KFM01606.1 - 0.23 11.4 4.5 0.82 9.7 3.1 2.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) RNA_pol_N PF01194.12 KFM01606.1 - 0.59 10.2 6.1 11 6.0 0.0 3.4 3 0 0 3 3 3 0 RNA polymerases N / 8 kDa subunit WW PF00397.21 KFM01607.1 - 1.3e-09 37.7 0.3 2.9e-09 36.6 0.2 1.6 1 0 0 1 1 1 1 WW domain DUF4498 PF14926.1 KFM01608.1 - 2.7e-99 331.3 1.4 3e-99 331.1 1.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4498) Fibrinogen_C PF00147.13 KFM01609.1 - 5.4e-58 196.3 2.0 7.2e-58 195.9 1.4 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Trypsin PF00089.21 KFM01610.1 - 3.1e-16 59.6 1.1 3.3e-16 59.5 0.8 1.0 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.21 KFM01611.1 - 2.2e-72 243.1 2.5 2.5e-72 243.0 1.7 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 KFM01611.1 - 0.0052 16.0 1.1 0.016 14.5 0.8 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 KFM01611.1 - 0.066 13.1 0.7 0.33 10.9 0.5 2.1 1 1 0 1 1 1 0 Trypsin-like peptidase domain Trypsin PF00089.21 KFM01612.1 - 1.1e-30 106.8 1.2 1.3e-30 106.6 0.8 1.0 1 0 0 1 1 1 1 Trypsin Pico_P2A PF00947.14 KFM01612.1 - 0.24 11.1 1.8 0.29 10.9 1.3 1.2 1 0 0 1 1 1 0 Picornavirus core protein 2A Trypsin PF00089.21 KFM01613.1 - 1.2e-66 224.4 0.9 1.3e-66 224.3 0.6 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 KFM01613.1 - 3.8e-05 23.1 0.0 6.4e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 KFM01613.1 - 0.004 17.1 0.0 0.01 15.8 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 KFM01614.1 - 2.5e-60 203.8 0.2 2.8e-60 203.6 0.2 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 KFM01614.1 - 0.00011 21.5 0.0 0.00015 21.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 KFM01614.1 - 0.0025 17.7 0.0 0.0042 17.0 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain BUD22 PF09073.5 KFM01615.1 - 3e-09 36.4 55.6 8.7e-06 25.0 38.5 3.1 1 1 0 1 1 1 1 BUD22 Lysyl_oxidase PF01186.12 KFM01616.1 - 5.5e-121 401.7 8.1 6.1e-121 401.5 5.6 1.0 1 0 0 1 1 1 1 Lysyl oxidase CARDB PF07705.6 KFM01616.1 - 0.0039 17.2 0.0 0.029 14.4 0.0 2.1 2 0 0 2 2 2 1 CARDB zf-C2HC_2 PF13913.1 KFM01617.1 - 2.9e-16 58.6 12.9 3.9e-09 35.9 1.9 2.8 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-C2H2 PF00096.21 KFM01617.1 - 0.0015 18.7 3.1 0.27 11.6 0.0 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type c-SKI_SMAD_bind PF08782.5 KFM01617.1 - 0.067 13.3 3.2 0.072 13.2 0.2 1.9 2 0 0 2 2 2 0 c-SKI Smad4 binding domain zf-C2H2_6 PF13912.1 KFM01617.1 - 0.08 12.8 5.9 1.4 8.8 0.7 2.8 2 1 0 2 2 2 0 C2H2-type zinc finger Rad50_zn_hook PF04423.9 KFM01617.1 - 0.12 11.9 0.6 0.23 10.9 0.1 1.7 2 0 0 2 2 2 0 Rad50 zinc hook motif Sgf11 PF08209.6 KFM01617.1 - 0.34 10.2 3.1 3.1 7.2 0.6 2.5 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) NinF PF05810.7 KFM01617.1 - 1.5 8.6 4.0 0.52 10.1 0.5 1.8 2 0 0 2 2 2 0 NinF protein zf-H2C2_2 PF13465.1 KFM01617.1 - 3.5 8.0 5.4 6 7.3 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2HC_2 PF13913.1 KFM01618.1 - 1.5e-20 72.3 4.3 1.2e-11 43.9 0.2 2.7 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-C2H2 PF00096.21 KFM01618.1 - 0.0024 18.1 3.1 0.068 13.5 0.1 2.8 3 0 0 3 3 3 1 Zinc finger, C2H2 type Sgf11 PF08209.6 KFM01618.1 - 0.017 14.4 1.1 0.61 9.4 0.1 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Lar_restr_allev PF14354.1 KFM01618.1 - 0.019 15.2 0.9 3.5 7.9 0.0 2.2 2 0 0 2 2 2 0 Restriction alleviation protein Lar zf-H2C2_2 PF13465.1 KFM01618.1 - 0.12 12.6 1.4 1.4 9.3 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger double domain zf-HC5HC2H PF13771.1 KFM01618.1 - 0.12 12.4 0.3 0.74 9.9 0.1 1.9 2 0 0 2 2 2 0 PHD-like zinc-binding domain BIR PF00653.16 KFM01618.1 - 0.56 10.6 2.6 13 6.2 1.2 2.7 1 1 1 2 2 2 0 Inhibitor of Apoptosis domain Prok-RING_1 PF14446.1 KFM01618.1 - 0.85 9.3 4.6 1.2 8.9 0.1 2.3 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 DUF4428 PF14471.1 KFM01618.1 - 1.1 9.0 4.8 3.3 7.5 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) zf-C2H2_4 PF13894.1 KFM01618.1 - 4.1 7.9 6.3 11 6.6 0.4 2.9 2 2 0 2 2 2 0 C2H2-type zinc finger Ank_2 PF12796.2 KFM01619.1 - 4e-20 71.9 3.3 6.8e-09 35.9 0.0 2.6 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFM01619.1 - 3.8e-17 62.2 0.2 2.6e-07 30.9 0.0 3.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM01619.1 - 7.7e-15 54.5 2.7 3.1e-05 24.0 0.0 4.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 KFM01619.1 - 4.9e-14 51.3 3.6 1.1e-07 31.2 0.2 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 KFM01619.1 - 4.5e-08 32.5 0.9 0.015 15.4 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Tubulin PF00091.20 KFM01620.1 - 1.5e-53 181.8 0.0 1.9e-53 181.4 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFM01620.1 - 8e-14 51.7 0.0 1.3e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KFM01620.1 - 0.0031 16.9 0.0 0.0058 16.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain PAP_central PF04928.12 KFM01621.1 - 0.025 13.3 0.4 0.028 13.2 0.2 1.0 1 0 0 1 1 1 0 Poly(A) polymerase central domain Peptidase_C65 PF10275.4 KFM01622.1 - 0.022 14.1 1.8 0.87 8.8 0.0 2.6 2 1 0 2 2 2 0 Peptidase C65 Otubain Peptidase_C65 PF10275.4 KFM01623.1 - 5.2e-05 22.7 3.0 0.00058 19.2 2.1 2.2 1 1 0 1 1 1 1 Peptidase C65 Otubain ANKH PF07260.6 KFM01624.1 - 4.5e-200 663.8 6.3 5.6e-200 663.5 4.3 1.1 1 0 0 1 1 1 1 Progressive ankylosis protein (ANKH) TMCO5 PF14992.1 KFM01624.1 - 0.066 12.3 0.3 0.11 11.6 0.2 1.2 1 0 0 1 1 1 0 TMCO5 family UCR_Fe-S_N PF10399.4 KFM01624.1 - 0.97 8.6 0.0 0.97 8.6 0.0 3.0 3 0 0 3 3 3 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal LRR_6 PF13516.1 KFM01625.1 - 5.1e-27 90.8 0.9 0.022 14.7 0.0 10.6 11 0 0 11 11 11 6 Leucine Rich repeat F-box-like PF12937.2 KFM01625.1 - 4.5e-17 61.4 4.1 1.2e-16 60.1 2.9 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KFM01625.1 - 2e-16 59.2 0.0 0.0057 16.2 0.0 6.6 2 1 6 8 8 8 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM01625.1 - 4.1e-16 56.5 6.9 0.49 10.6 0.0 10.8 10 1 0 10 10 10 3 Leucine Rich Repeat F-box PF00646.28 KFM01625.1 - 3.4e-12 45.6 1.9 3.4e-12 45.6 1.4 2.8 3 0 0 3 3 3 1 F-box domain LRR_7 PF13504.1 KFM01625.1 - 1.1e-11 42.9 10.1 1.9 9.0 0.0 9.9 10 1 0 10 10 10 2 Leucine rich repeat LRR_8 PF13855.1 KFM01625.1 - 3.2e-08 33.2 1.0 0.37 10.5 0.0 5.9 3 2 2 5 5 5 3 Leucine rich repeat zf-C2H2_2 PF12756.2 KFM01626.1 - 1e-36 125.0 11.1 1.7e-29 101.8 0.3 3.4 2 1 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KFM01626.1 - 1.4e-12 47.3 13.9 5.7e-09 35.8 1.8 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM01626.1 - 4.8e-05 23.4 3.3 4.8e-05 23.4 2.3 3.5 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-DBF PF07535.7 KFM01626.1 - 0.0028 17.2 0.5 0.0028 17.2 0.3 3.0 3 0 0 3 3 3 1 DBF zinc finger zf-C2H2_4 PF13894.1 KFM01626.1 - 0.0065 16.7 1.3 0.0065 16.7 0.9 3.1 3 0 0 3 3 2 1 C2H2-type zinc finger DUF629 PF04780.7 KFM01626.1 - 0.0075 14.8 0.5 0.0075 14.8 0.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF629) zf-C2H2_6 PF13912.1 KFM01626.1 - 0.016 15.0 1.3 0.016 15.0 0.9 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger GCP5-Mod21 PF14609.1 KFM01626.1 - 0.075 11.1 4.1 0.12 10.4 2.8 1.3 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 SecA_PP_bind PF01043.15 KFM01626.1 - 0.13 12.6 1.9 3.4 8.0 0.0 2.5 2 0 0 2 2 2 0 SecA preprotein cross-linking domain TRAP_alpha PF03896.11 KFM01626.1 - 0.39 9.6 5.8 0.82 8.6 4.0 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit zf-LYAR PF08790.6 KFM01626.1 - 4.5 7.0 7.6 8.3 6.2 0.2 3.3 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger Reticulon PF02453.12 KFM01627.1 - 0.027 14.0 1.6 0.053 13.1 1.1 1.4 1 0 0 1 1 1 0 Reticulon ALMT PF11744.3 KFM01627.1 - 0.12 11.0 0.3 0.82 8.2 0.0 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter Myosin_head PF00063.16 KFM01628.1 - 1.3e-224 747.2 4.4 2.1e-224 746.6 3.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) MyTH4 PF00784.12 KFM01628.1 - 8.7e-34 115.9 0.0 3.5e-33 113.9 0.0 2.2 1 0 0 1 1 1 1 MyTH4 domain PH PF00169.24 KFM01628.1 - 7.2e-33 112.9 14.0 2e-15 56.8 0.1 5.4 4 1 1 5 5 5 4 PH domain FERM_M PF00373.13 KFM01628.1 - 2.8e-21 76.0 0.6 2.8e-21 76.0 0.4 2.9 2 0 0 2 2 1 1 FERM central domain PH_11 PF15413.1 KFM01628.1 - 3.4e-16 59.4 9.7 2.1e-09 37.6 0.0 4.9 3 1 1 4 4 4 3 Pleckstrin homology domain PH_8 PF15409.1 KFM01628.1 - 1.5e-12 47.4 5.3 3.9e-09 36.4 0.1 3.9 4 0 0 4 4 3 2 Pleckstrin homology domain PH_3 PF14593.1 KFM01628.1 - 5.1e-11 42.3 1.2 3.7e-07 29.9 0.1 3.8 2 1 1 3 3 3 2 PH domain IQ PF00612.22 KFM01628.1 - 3.1e-05 23.2 21.2 0.16 11.6 2.1 3.9 3 0 0 3 3 3 3 IQ calmodulin-binding motif RA PF00788.18 KFM01628.1 - 7.5e-05 23.1 0.0 0.00079 19.8 0.0 2.8 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain AAA_16 PF13191.1 KFM01628.1 - 0.04 13.9 0.0 0.04 13.9 0.0 3.5 2 1 0 2 2 1 0 AAA ATPase domain AAA_22 PF13401.1 KFM01628.1 - 0.15 12.1 0.0 0.15 12.1 0.0 2.7 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.22 KFM01628.1 - 0.69 10.2 5.4 2.1 8.6 0.0 3.0 2 0 0 2 2 2 0 ABC transporter BASP1 PF05466.7 KFM01629.1 - 2.3e-95 318.9 94.8 2.5e-95 318.7 65.7 1.0 1 0 0 1 1 1 1 Brain acid soluble protein 1 (BASP1 protein) Utp14 PF04615.8 KFM01629.1 - 5.5 5.0 52.9 6.5 4.7 36.6 1.0 1 0 0 1 1 1 0 Utp14 protein Cadherin PF00028.12 KFM01632.1 - 3.5e-85 280.3 6.9 1.3e-20 73.4 0.1 5.2 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.12 KFM01632.1 - 1e-53 181.3 0.9 2.6e-53 180.0 0.6 1.7 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.7 KFM01632.1 - 4.1e-05 23.0 0.0 0.26 10.8 0.0 4.3 4 0 0 4 4 4 1 Cadherin-like DUF2207 PF09972.4 KFM01632.1 - 0.03 12.9 0.0 0.77 8.2 0.0 2.3 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) ASFV_J13L PF05568.6 KFM01632.1 - 0.062 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein Methyltransf_16 PF10294.4 KFM01633.1 - 4.9e-34 117.2 0.0 6e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 KFM01633.1 - 1.4e-07 31.3 0.0 2.1e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFM01633.1 - 0.00015 22.2 0.0 0.00024 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KFM01633.1 - 0.006 15.7 0.0 0.0074 15.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.15 KFM01633.1 - 0.039 12.9 0.0 0.053 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.7 KFM01633.1 - 0.1 13.1 0.1 0.27 11.7 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain XPG_N PF00752.12 KFM01634.1 - 5.2e-33 113.3 0.0 1.5e-32 111.8 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 KFM01634.1 - 1.2e-23 83.0 0.3 1.1e-22 79.8 0.0 2.9 3 0 0 3 3 3 1 XPG I-region 5_3_exonuc PF01367.15 KFM01634.1 - 0.0069 16.6 1.3 0.044 14.0 0.0 3.1 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold Glyco_transf_90 PF05686.7 KFM01636.1 - 2.3e-111 372.2 1.3 3.2e-111 371.8 0.9 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Filamin PF00630.14 KFM01636.1 - 2.6e-07 31.1 0.0 5.1e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Filamin/ABP280 repeat Glyco_trans_1_2 PF13524.1 KFM01636.1 - 1.4e-05 25.2 0.0 2.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Abhydrolase_5 PF12695.2 KFM01637.1 - 1.1e-20 73.9 0.0 1.3e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFM01637.1 - 1e-07 32.0 0.2 0.001 19.0 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family DLH PF01738.13 KFM01637.1 - 0.00047 19.5 0.0 0.0014 17.9 0.0 1.8 1 1 0 2 2 2 1 Dienelactone hydrolase family FSH1 PF03959.8 KFM01637.1 - 0.0024 17.3 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Methyltransf_16 PF10294.4 KFM01638.1 - 6.2e-32 110.4 0.0 7.4e-32 110.1 0.0 1.0 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 KFM01638.1 - 2.6e-11 43.5 0.0 3.3e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFM01638.1 - 4.7e-06 27.1 0.0 8.1e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KFM01638.1 - 5.8e-05 22.3 0.0 6.8e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.7 KFM01638.1 - 8.8e-05 22.9 0.0 0.00015 22.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFM01638.1 - 0.00023 21.6 0.0 0.00034 21.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 KFM01638.1 - 0.007 15.6 0.0 0.0092 15.3 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase MTS PF05175.9 KFM01638.1 - 0.0074 15.6 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 KFM01638.1 - 0.019 14.5 0.1 0.11 12.0 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 KFM01638.1 - 0.038 14.0 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 KFM01638.1 - 0.046 12.8 0.0 0.11 11.6 0.0 1.6 1 1 0 1 1 1 0 Tellurite resistance protein TehB DREV PF05219.7 KFM01638.1 - 0.066 12.0 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase Med31 PF05669.7 KFM01638.1 - 0.088 12.5 0.1 1.7 8.4 0.1 2.6 3 0 0 3 3 3 0 SOH1 DUF938 PF06080.7 KFM01638.1 - 0.13 11.7 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Receptor_IA-2 PF11548.3 KFM01638.1 - 0.15 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase receptor IA-2 TPPII PF12580.3 KFM01639.1 - 6.7e-92 306.1 0.0 1.9e-91 304.6 0.0 1.8 2 0 0 2 2 2 1 Tripeptidyl peptidase II Peptidase_S8 PF00082.17 KFM01639.1 - 7.3e-74 248.4 1.1 9.9e-74 248.0 0.8 1.2 1 0 0 1 1 1 1 Subtilase family TPPII_N PF12583.3 KFM01639.1 - 0.00061 19.9 0.1 0.0012 18.9 0.1 1.4 1 0 0 1 1 1 1 Tripeptidyl peptidase II N terminal DUF4399 PF14347.1 KFM01639.1 - 0.053 13.5 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4399) IncA PF04156.9 KFM01639.1 - 2 7.9 4.9 0.21 11.1 0.2 1.6 2 0 0 2 2 2 0 IncA protein FGF PF00167.13 KFM01640.1 - 8.4e-43 145.0 0.0 1.1e-42 144.7 0.0 1.1 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.8 KFM01640.1 - 0.017 15.2 0.0 0.045 13.8 0.0 1.6 2 0 0 2 2 2 0 Fascin domain CDtoxinA PF03498.9 KFM01640.1 - 0.15 11.4 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Cytolethal distending toxin A/C family EGF_2 PF07974.8 KFM01642.1 - 3.8e-41 138.9 207.1 5.8e-07 29.5 12.3 10.2 8 3 1 10 10 10 9 EGF-like domain hEGF PF12661.2 KFM01642.1 - 0.012 15.6 2.4 0.012 15.6 1.6 14.2 20 0 0 20 20 20 0 Human growth factor-like EGF EGF PF00008.22 KFM01642.1 - 0.022 14.6 9.6 0.022 14.6 6.7 11.6 8 2 1 10 10 10 0 EGF-like domain TPR_11 PF13414.1 KFM01644.1 - 5.7e-42 141.2 41.1 3.4e-12 45.8 0.5 5.6 1 1 6 7 7 7 7 TPR repeat TPR_1 PF00515.23 KFM01644.1 - 9.5e-34 113.6 19.6 6.7e-05 22.3 0.4 7.6 7 0 0 7 7 7 7 Tetratricopeptide repeat DUF1736 PF08409.6 KFM01644.1 - 8.6e-33 111.7 2.5 1.8e-32 110.7 1.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_17 PF13431.1 KFM01644.1 - 1.6e-28 96.4 21.2 6.8e-06 25.8 0.2 7.9 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_2 PF07719.12 KFM01644.1 - 3.1e-28 95.3 17.4 9.1e-06 25.2 0.2 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.1 KFM01644.1 - 9.5e-27 92.7 17.0 9.5e-09 35.0 0.4 5.3 1 1 5 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 KFM01644.1 - 3.3e-25 88.1 9.7 1.9e-06 28.3 0.1 4.8 2 1 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 KFM01644.1 - 6.9e-22 75.5 12.8 5e-05 22.7 0.3 7.4 6 1 1 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.1 KFM01644.1 - 3.6e-19 67.5 12.0 0.00098 19.5 0.1 8.3 2 1 7 9 9 9 6 Tetratricopeptide repeat TPR_19 PF14559.1 KFM01644.1 - 1.2e-13 51.1 10.3 1.2e-05 25.4 0.8 5.1 2 1 5 7 7 6 5 Tetratricopeptide repeat TPR_10 PF13374.1 KFM01644.1 - 2e-10 40.2 21.6 0.00095 19.0 0.3 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.1 KFM01644.1 - 1.4e-09 37.0 6.5 1.3 8.9 0.1 6.9 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_6 PF13174.1 KFM01644.1 - 4e-05 23.7 5.1 1.8 9.1 0.0 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_4 PF07721.9 KFM01644.1 - 7.7e-05 22.7 0.0 3.3 8.3 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 KFM01644.1 - 0.005 16.9 8.5 0.28 11.3 0.5 3.6 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KFM01644.1 - 0.0054 16.5 1.4 0.19 11.6 0.1 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat NARP1 PF12569.3 KFM01644.1 - 0.0069 15.2 1.6 0.38 9.4 0.1 2.4 2 1 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_20 PF14561.1 KFM01644.1 - 0.028 14.5 3.2 0.73 9.9 0.1 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.12 KFM01644.1 - 0.11 12.7 1.0 6.1 7.1 0.0 2.6 3 0 0 3 3 2 0 Bacterial transcriptional activator domain AIG2 PF06094.7 KFM01645.1 - 9.2e-20 71.0 0.1 1.2e-19 70.7 0.1 1.2 1 0 0 1 1 1 1 AIG2-like family AIG2_2 PF13772.1 KFM01645.1 - 0.067 13.3 0.0 0.12 12.4 0.0 1.5 1 1 0 1 1 1 0 AIG2-like family CPSase_L_D2 PF02786.12 KFM01646.1 - 3.6e-84 281.2 0.0 6e-84 280.5 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 KFM01646.1 - 4.6e-31 106.9 0.0 1.2e-30 105.6 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 KFM01646.1 - 6.1e-29 100.3 0.2 1.8e-28 98.8 0.1 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 KFM01646.1 - 3.1e-13 49.8 0.0 6.8e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 KFM01646.1 - 1.1e-12 47.3 3.2 2.1e-12 46.5 1.1 2.3 3 0 0 3 3 3 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 KFM01646.1 - 5.2e-10 38.5 0.1 1e-09 37.6 0.1 1.4 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KFM01646.1 - 3.2e-07 29.9 0.0 2.1e-06 27.2 0.0 2.2 1 1 1 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KFM01646.1 - 2e-06 27.3 0.0 4.9e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 KFM01646.1 - 2.1e-06 27.3 0.0 4.2e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Biotin_lipoyl_2 PF13533.1 KFM01646.1 - 1.9e-05 24.2 0.0 5.2e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Biotin-lipoyl like ATP-grasp_3 PF02655.9 KFM01646.1 - 0.0019 18.0 0.0 0.0048 16.7 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain SLT_beta PF02258.11 KFM01646.1 - 0.002 17.9 0.2 0.0061 16.3 0.0 1.9 2 0 0 2 2 2 1 Shiga-like toxin beta subunit ATP-grasp_5 PF13549.1 KFM01646.1 - 0.019 14.2 0.1 0.071 12.3 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp domain GARS_A PF01071.14 KFM01646.1 - 0.037 13.5 0.0 0.082 12.4 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HlyD_3 PF13437.1 KFM01646.1 - 0.086 13.1 0.0 0.24 11.7 0.0 1.8 1 0 0 1 1 1 0 HlyD family secretion protein zf-C2H2 PF00096.21 KFM01647.1 - 1.4e-13 50.2 10.6 7.5e-06 25.9 0.1 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM01647.1 - 1.1e-11 44.2 4.9 0.00079 19.5 0.1 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFM01647.1 - 9.2e-10 38.3 14.5 7.5e-09 35.4 0.2 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFM01647.1 - 0.0015 18.5 2.1 0.27 11.4 0.1 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding HpcH_HpaI PF03328.9 KFM01648.1 - 1.9e-46 157.7 0.0 2.5e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 KFM01648.1 - 8.1e-11 41.3 0.1 6.9e-07 28.3 0.0 2.2 1 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold 7tm_1 PF00001.16 KFM01649.1 - 1e-52 178.8 14.2 1.2e-52 178.5 9.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 KFM01649.1 - 0.0012 18.6 2.4 0.0012 18.6 1.6 2.8 2 1 1 3 3 3 1 Olfactory receptor DUF3357 PF11837.3 KFM01649.1 - 0.047 13.5 0.5 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) TAS2R PF05296.8 KFM01649.1 - 0.13 11.1 8.3 0.5 9.1 1.9 2.2 2 0 0 2 2 2 0 Mammalian taste receptor protein (TAS2R) Na_Ca_ex PF01699.19 KFM01649.1 - 4.9 6.7 9.0 0.33 10.5 0.5 2.7 2 1 1 3 3 3 0 Sodium/calcium exchanger protein DUF4131 PF13567.1 KFM01649.1 - 6.3 6.1 9.4 0.53 9.6 0.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) UBA PF00627.26 KFM01650.1 - 6.9e-13 48.0 0.4 1.3e-12 47.1 0.3 1.5 1 0 0 1 1 1 1 UBA/TS-N domain FeoA PF04023.9 KFM01650.1 - 0.045 13.7 0.1 0.19 11.6 0.0 1.9 2 0 0 2 2 2 0 FeoA domain TetR_C PF02909.12 KFM01650.1 - 0.088 12.4 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 Tetracyclin repressor, C-terminal all-alpha domain 7tm_1 PF00001.16 KFM01651.1 - 1.7e-58 197.7 16.4 2.1e-58 197.4 11.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 KFM01651.1 - 0.00067 19.4 9.5 0.00067 19.4 6.6 3.0 2 1 2 4 4 4 1 Olfactory receptor 7TM_GPCR_Srd PF10317.4 KFM01651.1 - 3.8 6.4 32.7 32 3.3 22.5 2.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd P12 PF12669.2 KFM01651.1 - 4.7 7.4 5.5 19 5.5 0.0 3.1 3 0 0 3 3 3 0 Virus attachment protein p12 family 7tm_1 PF00001.16 KFM01652.1 - 2.4e-37 128.4 23.5 3e-37 128.1 16.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4013 PF13197.1 KFM01652.1 - 0.0019 17.5 2.9 0.0019 17.5 2.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF4013) Ded_cyto PF06920.8 KFM01653.1 - 1.9e-65 219.4 1.1 1.9e-65 219.4 0.7 2.7 3 0 0 3 3 3 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 KFM01653.1 - 1.8e-58 197.2 1.1 6e-58 195.5 0.4 2.3 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.3 KFM01653.1 - 8.2e-31 105.7 0.2 2.4e-30 104.2 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3398) PH PF00169.24 KFM01653.1 - 1.2e-12 47.9 0.2 7.5e-12 45.3 0.1 2.5 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 KFM01653.1 - 2.7e-05 24.3 0.0 0.00016 21.7 0.0 2.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 KFM01653.1 - 0.022 14.8 0.1 0.068 13.2 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain PTR2 PF00854.16 KFM01654.1 - 2.4e-122 408.3 14.5 4.1e-119 397.6 7.7 2.2 2 0 0 2 2 2 2 POT family DUF4397 PF14344.1 KFM01654.1 - 0.0023 18.2 0.2 0.013 15.8 0.1 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4397) DUF2207 PF09972.4 KFM01654.1 - 0.13 10.8 2.7 0.6 8.6 0.3 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Pkinase PF00069.20 KFM01655.1 - 3.7e-73 245.8 0.0 4.9e-73 245.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM01655.1 - 1.5e-54 184.8 0.0 2e-54 184.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1241 PF06840.6 KFM01655.1 - 0.00014 21.1 0.0 0.00035 19.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Kinase-like PF14531.1 KFM01655.1 - 0.00069 18.6 0.0 0.0017 17.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KFM01655.1 - 0.02 14.6 0.0 3.4 7.3 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KFM01655.1 - 0.066 12.2 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4288 PF14119.1 KFM01655.1 - 0.11 12.5 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) RhoGEF PF00621.15 KFM01656.1 - 4.5e-31 108.1 1.7 4.5e-31 108.1 1.2 1.9 2 0 0 2 2 2 1 RhoGEF domain FERM_C PF09380.5 KFM01656.1 - 2.3e-25 88.5 0.4 5.7e-25 87.3 0.3 1.7 1 0 0 1 1 1 1 FERM C-terminal PH-like domain PH PF00169.24 KFM01656.1 - 9.2e-25 86.8 0.5 2.8e-15 56.3 0.6 2.7 2 0 0 2 2 2 2 PH domain FA PF08736.6 KFM01656.1 - 4.7e-16 58.2 3.6 1.1e-15 57.1 1.7 2.4 2 0 0 2 2 2 1 FERM adjacent (FA) FERM_N PF09379.5 KFM01656.1 - 1.3e-13 50.7 0.1 4.6e-13 49.0 0.1 2.1 1 0 0 1 1 1 1 FERM N-terminal domain FERM_M PF00373.13 KFM01656.1 - 7.9e-13 48.6 1.2 7.9e-13 48.6 0.8 2.4 2 1 0 2 2 2 1 FERM central domain HEAT_2 PF13646.1 KFM01657.1 - 2.9e-21 75.5 1.3 1.2e-11 44.6 0.0 6.4 5 1 1 6 6 6 2 HEAT repeats HEAT PF02985.17 KFM01657.1 - 4.3e-20 69.9 8.6 9.2e-06 25.3 0.0 8.8 9 0 0 9 9 9 4 HEAT repeat HEAT_EZ PF13513.1 KFM01657.1 - 1.1e-18 67.1 1.1 9.1e-07 29.1 0.0 8.0 8 0 0 8 8 8 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KFM01657.1 - 1.2e-12 48.0 6.4 1.6e-06 28.4 0.0 8.1 6 2 3 9 9 9 2 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 KFM01657.1 - 2.9e-05 23.8 0.1 0.0011 18.8 0.0 3.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Arm PF00514.18 KFM01657.1 - 0.00013 21.6 1.8 12 5.8 0.0 6.1 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.11 KFM01657.1 - 1 10.0 4.8 28 5.5 0.0 4.5 4 1 0 4 4 4 0 PBS lyase HEAT-like repeat zf-CCCH PF00642.19 KFM01658.1 - 1.1e-10 40.8 22.1 0.00019 21.0 0.5 4.6 4 1 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SERTA PF06031.8 KFM01660.1 - 1.1e-18 66.2 3.5 1.5e-18 65.7 1.8 1.8 2 0 0 2 2 2 1 SERTA motif Glycohydro_20b2 PF14845.1 KFM01660.1 - 0.039 14.6 0.1 0.06 14.0 0.1 1.4 1 1 0 1 1 1 0 beta-acetyl hexosaminidase like EGF PF00008.22 KFM01661.1 - 1.9e-68 225.8 283.0 2.2e-08 33.8 5.4 18.7 19 0 0 19 19 19 14 EGF-like domain MNNL PF07657.8 KFM01661.1 - 2.6e-27 94.5 1.1 2.6e-27 94.5 0.7 5.3 6 0 0 6 6 6 1 N terminus of Notch ligand DSL PF01414.14 KFM01661.1 - 9.2e-27 92.8 6.4 9.2e-27 92.8 4.4 13.4 9 3 7 16 16 16 1 Delta serrate ligand hEGF PF12661.2 KFM01661.1 - 6.9e-17 60.2 170.3 0.0059 16.6 4.0 19.3 18 0 0 18 18 18 13 Human growth factor-like EGF EGF_2 PF07974.8 KFM01661.1 - 2e-15 56.6 325.4 0.0061 16.6 5.0 20.0 20 0 0 20 20 20 14 EGF-like domain EGF_CA PF07645.10 KFM01661.1 - 3.7e-06 26.8 21.4 4e-05 23.5 5.0 19.9 9 4 11 20 20 20 10 Calcium-binding EGF domain HSA PF07529.8 KFM01661.1 - 0.16 11.7 0.8 0.48 10.2 0.6 1.8 1 0 0 1 1 1 0 HSA PepSY_TM_2 PF13703.1 KFM01661.1 - 0.18 11.9 0.0 0.32 11.1 0.0 1.3 1 0 0 1 1 1 0 PepSY-associated TM helix EspB PF05802.6 KFM01661.1 - 0.94 8.3 2.3 8.4 5.2 0.1 2.0 2 0 0 2 2 2 0 Enterobacterial EspB protein NUDIX PF00293.23 KFM01662.1 - 2.8e-19 69.0 0.0 3.6e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain ESPR PF13018.1 KFM01662.1 - 0.018 14.6 0.4 0.036 13.6 0.3 1.5 1 0 0 1 1 1 0 Extended Signal Peptide of Type V secretion system AAA_2 PF07724.9 KFM01663.1 - 7.7e-46 156.1 0.5 1.5e-45 155.1 0.3 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KFM01663.1 - 6e-10 38.9 0.0 2.4e-09 37.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.4 KFM01663.1 - 6.4e-10 38.8 0.2 2.4e-09 36.9 0.0 2.1 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 KFM01663.1 - 1.1e-08 35.3 0.0 1.1e-07 32.0 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KFM01663.1 - 5.5e-06 25.6 0.0 1.6e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 KFM01663.1 - 5e-05 22.8 0.0 8.5e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.1 KFM01663.1 - 0.00051 20.0 0.2 0.0019 18.2 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KFM01663.1 - 0.00078 19.5 0.0 0.0026 17.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain Torsin PF06309.6 KFM01663.1 - 0.0024 17.7 0.0 0.008 16.0 0.0 1.9 2 0 0 2 2 2 1 Torsin AAA_3 PF07726.6 KFM01663.1 - 0.0027 17.2 0.0 0.041 13.4 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KFM01663.1 - 0.0052 17.6 0.1 0.023 15.5 0.1 2.4 1 1 0 1 1 1 1 AAA domain YchF-GTPase_C PF06071.8 KFM01663.1 - 0.0092 15.7 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) ABC_tran PF00005.22 KFM01663.1 - 0.014 15.7 0.1 0.11 12.7 0.1 2.4 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 KFM01663.1 - 0.016 15.1 0.0 0.088 12.7 0.0 2.2 1 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KFM01663.1 - 0.016 14.8 0.7 0.11 12.2 0.5 2.5 1 1 0 1 1 1 0 Archaeal ATPase AAA_24 PF13479.1 KFM01663.1 - 0.095 12.2 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ank PF00023.25 KFM01664.1 - 3.4e-11 42.3 0.1 5e-09 35.5 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KFM01664.1 - 1.3e-10 41.4 0.0 1.4e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFM01664.1 - 8.3e-08 32.5 0.3 0.0018 18.7 0.0 1.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM01664.1 - 7e-07 29.2 0.1 7.9e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM01664.1 - 7.2e-07 28.8 0.1 1.1e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat MRL1 PF13003.2 KFM01665.1 - 1.4e-20 73.4 0.2 2.3e-20 72.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L1 Ribosomal_L1 PF00687.16 KFM01665.1 - 2.2e-06 27.2 1.9 3.9e-06 26.3 1.1 1.6 1 1 1 2 2 2 1 Ribosomal protein L1p/L10e family Exo_endo_phos PF03372.18 KFM01666.1 - 6.1e-21 75.4 0.0 8e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 KFM01666.1 - 1.2e-14 53.5 17.4 4.4e-10 38.9 1.9 3.0 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM01666.1 - 9.5e-11 41.2 11.6 1.8e-10 40.4 6.2 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 KFM01666.1 - 1.1e-06 27.8 18.4 0.017 15.0 0.1 5.7 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 KFM01666.1 - 0.003 17.4 17.4 0.3 11.4 0.3 5.2 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 KFM01666.1 - 0.66 10.2 14.7 3.1 8.1 0.2 4.6 4 0 0 4 4 4 0 Leucine Rich repeat IL8 PF00048.15 KFM01667.1 - 3.9e-11 42.7 0.5 4.1e-11 42.6 0.4 1.0 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like IL8 PF00048.15 KFM01668.1 - 3.1e-15 55.8 0.4 3.4e-15 55.7 0.3 1.0 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like Cyclin_N PF00134.18 KFM01669.1 - 3.3e-17 62.2 0.5 3.3e-17 62.2 0.4 1.8 1 1 1 2 2 2 1 Cyclin, N-terminal domain Cyclin_N PF00134.18 KFM01670.1 - 4.6e-25 87.6 0.1 1.1e-24 86.4 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFM01670.1 - 0.002 18.0 3.7 0.0087 15.9 1.5 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain Septin PF00735.13 KFM01672.1 - 4.6e-99 330.9 1.3 4.6e-99 330.9 0.9 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KFM01672.1 - 8.9e-07 28.8 0.5 2.3e-06 27.5 0.0 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KFM01672.1 - 0.0011 19.0 0.7 0.0044 17.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain Ras PF00071.17 KFM01672.1 - 0.0015 17.9 0.0 0.0048 16.2 0.0 1.9 1 0 0 1 1 1 1 Ras family AAA_16 PF13191.1 KFM01672.1 - 0.0022 18.0 0.4 0.0067 16.4 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 KFM01672.1 - 0.0062 16.0 1.0 0.015 14.7 0.7 1.8 1 1 0 1 1 1 1 AAA-like domain GTP_EFTU PF00009.22 KFM01672.1 - 0.0097 15.3 3.6 1.3 8.3 0.0 3.1 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 KFM01672.1 - 0.015 14.8 0.1 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 KFM01672.1 - 0.028 14.9 1.7 0.061 13.8 0.0 2.6 2 1 0 2 2 2 0 Miro-like protein FtsK_SpoIIIE PF01580.13 KFM01672.1 - 0.13 11.7 3.1 1 8.7 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_tran PF00005.22 KFM01672.1 - 0.21 11.8 0.1 0.21 11.8 0.1 2.6 2 2 0 2 2 1 0 ABC transporter Dynamin_N PF00350.18 KFM01672.1 - 0.27 11.0 9.3 3.8 7.2 0.1 3.4 2 1 0 2 2 2 0 Dynamin family DUF87 PF01935.12 KFM01672.1 - 0.55 10.0 9.2 1.7 8.4 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF87 Fzo_mitofusin PF04799.8 KFM01672.1 - 1 8.7 11.1 0.75 9.1 6.2 1.8 2 0 0 2 2 2 0 fzo-like conserved region IncA PF04156.9 KFM01672.1 - 2.6 7.6 13.9 4.6 6.7 9.6 1.4 1 0 0 1 1 1 0 IncA protein AAA_11 PF13086.1 KFM01672.1 - 3.8 7.0 11.9 7.5 6.0 7.9 1.7 1 1 0 1 1 1 0 AAA domain Ank_5 PF13857.1 KFM01673.1 - 6.2e-13 48.5 0.1 1.4e-09 37.8 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KFM01673.1 - 1.3e-09 37.3 0.5 1.1e-06 28.1 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 KFM01673.1 - 8.1e-09 35.7 0.5 1e-05 25.9 0.1 1.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KFM01673.1 - 3.2e-07 30.5 0.0 2.1e-06 27.9 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KFM01673.1 - 0.00014 21.7 0.1 0.038 14.2 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Gal-bind_lectin PF00337.17 KFM01674.1 - 1.5e-31 108.5 0.0 1.6e-31 108.4 0.0 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin IncA PF04156.9 KFM01675.1 - 0.14 11.6 64.4 0.56 9.7 0.2 4.3 3 1 1 4 4 4 0 IncA protein CD36 PF01130.16 KFM01676.1 - 5.3e-144 480.0 0.5 6e-144 479.8 0.4 1.0 1 0 0 1 1 1 1 CD36 family TMEM154 PF15102.1 KFM01676.1 - 0.025 14.3 0.2 0.042 13.5 0.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family Nup54 PF13874.1 KFM01677.1 - 5.2e-49 165.5 4.1 5.2e-49 165.5 2.8 2.1 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 FAST_2 PF08368.7 KFM01677.1 - 0.01 16.1 0.5 0.067 13.5 0.0 2.5 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 2 Nucleoporin_FG PF13634.1 KFM01677.1 - 5 7.3 42.0 9.2 6.5 29.1 1.4 1 0 0 1 1 1 0 Nucleoporin FG repeat region Metallophos PF00149.23 KFM01678.1 - 1.1e-40 139.2 0.0 2.5e-40 138.0 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_1 PF00036.27 KFM01678.1 - 3.5e-18 63.4 1.5 6.7e-06 25.0 0.0 3.7 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 KFM01678.1 - 2.1e-16 59.8 9.5 9.1e-10 38.5 2.9 2.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KFM01678.1 - 1.9e-14 52.2 2.5 0.00067 18.8 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 KFM01678.1 - 4.5e-14 50.9 1.9 0.0035 17.1 0.0 3.9 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 KFM01678.1 - 1.3e-13 50.3 3.5 4.9e-06 26.0 0.0 4.0 3 1 1 4 4 4 2 EF-hand domain pair PPP5 PF08321.7 KFM01678.1 - 1.1e-10 41.3 0.1 3.5e-09 36.5 0.0 3.0 2 1 1 3 3 3 1 PPP5 TPR repeat region EF-hand_4 PF12763.2 KFM01678.1 - 0.0003 20.4 1.7 0.29 10.8 0.3 3.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand IQ PF00612.22 KFM01678.1 - 0.0016 17.8 2.5 0.0044 16.5 1.7 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif NAAA-beta PF15508.1 KFM01679.1 - 1.8e-10 40.9 0.0 4.2e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase CBAH PF02275.13 KFM01679.1 - 3.1e-08 33.4 0.0 0.00012 21.6 0.0 2.2 2 0 0 2 2 2 2 Linear amide C-N hydrolases, choloylglycine hydrolase family SDA1 PF05285.7 KFM01680.1 - 6.1e-69 232.7 44.4 9.5e-67 225.5 23.4 3.1 2 1 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 KFM01680.1 - 1.5e-25 89.2 0.8 1.5e-25 89.2 0.5 3.2 4 0 0 4 4 4 1 NUC130/3NT domain Ig_J_chain PF15097.1 KFM01681.1 - 4.4e-69 230.2 6.5 5e-69 230.0 4.5 1.0 1 0 0 1 1 1 1 Immunoglobulin J chain CBM_5_12 PF02839.9 KFM01681.1 - 0.02 14.4 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain Toxin_44 PF15523.1 KFM01681.1 - 0.026 14.4 0.7 8.6 6.3 0.0 2.3 2 0 0 2 2 2 0 Putative toxin 44 Sas10 PF09368.5 KFM01682.1 - 7.9e-27 93.2 11.7 7.9e-27 93.2 8.1 2.2 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 KFM01682.1 - 3.8e-16 59.0 2.3 8.8e-16 57.8 0.1 2.5 2 0 0 2 2 2 1 Sas10/Utp3/C1D family PRP1_N PF06424.7 KFM01682.1 - 9.9 6.4 16.6 2.1 8.6 4.9 2.6 1 1 2 3 3 3 0 PRP1 splicing factor, N-terminal RUN PF02759.14 KFM01683.1 - 2.8e-33 114.5 0.1 4.8e-32 110.4 0.0 2.4 2 0 0 2 2 2 1 RUN domain Macoilin PF09726.4 KFM01683.1 - 0.25 9.5 20.2 0.35 9.1 14.0 1.2 1 0 0 1 1 1 0 Transmembrane protein ATG16 PF08614.6 KFM01683.1 - 0.27 11.0 23.1 0.098 12.4 7.2 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) UPF0449 PF15136.1 KFM01683.1 - 0.44 10.7 0.1 0.44 10.7 0.1 3.8 2 1 2 4 4 4 0 Uncharacterised protein family UPF0449 OmpH PF03938.9 KFM01683.1 - 0.95 9.3 0.0 0.95 9.3 0.0 3.4 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) Reo_sigmaC PF04582.7 KFM01683.1 - 2.9 6.9 7.7 7.3 5.6 2.6 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 KFM01683.1 - 3.6 7.3 26.2 3.4 7.4 3.6 3.4 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.7 KFM01683.1 - 3.7 7.3 20.1 0.89 9.3 0.3 3.3 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Sod_Fe_N PF00081.17 KFM01683.1 - 6.1 7.1 6.5 0.43 10.8 0.2 2.3 3 0 0 3 3 3 0 Iron/manganese superoxide dismutases, alpha-hairpin domain RRM_6 PF14259.1 KFM01684.1 - 2.9e-36 123.2 0.0 4.6e-12 45.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFM01684.1 - 2.8e-18 65.3 0.8 1e-06 28.2 0.0 3.8 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM01684.1 - 0.0001 22.0 0.0 4.5 7.1 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFM01684.1 - 0.0024 17.6 0.0 2.1 8.2 0.0 2.5 2 0 0 2 2 2 2 RNA binding motif Aldo_ket_red PF00248.16 KFM01684.1 - 0.04 12.7 0.2 1.9 7.2 0.0 2.3 1 1 0 2 2 2 0 Aldo/keto reductase family DUF3184 PF11380.3 KFM01684.1 - 0.051 11.5 0.0 0.068 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3184) Nup35_RRM_2 PF14605.1 KFM01684.1 - 0.081 12.7 0.1 12 5.8 0.0 3.5 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Mob1_phocein PF03637.12 KFM01685.1 - 1.6e-80 268.8 0.4 1.9e-80 268.6 0.3 1.0 1 0 0 1 1 1 1 Mob1/phocein family dNK PF01712.14 KFM01686.1 - 4.8e-46 156.3 1.8 6.3e-46 155.9 1.2 1.2 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.1 KFM01686.1 - 9.7e-07 29.1 0.0 2.3e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KFM01686.1 - 3e-05 24.0 0.1 7.7e-05 22.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFM01686.1 - 0.00036 20.4 0.0 0.0017 18.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 KFM01686.1 - 0.0016 17.8 0.1 0.02 14.2 0.0 2.3 2 1 0 2 2 2 1 Thymidylate kinase AAA_17 PF13207.1 KFM01686.1 - 0.021 15.6 0.8 0.15 12.9 0.6 2.4 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 KFM01686.1 - 0.082 12.7 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Dynamin family HCO3_cotransp PF00955.16 KFM01687.1 - 5.8e-246 817.0 8.3 7.2e-246 816.7 5.8 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.8 KFM01687.1 - 5.4e-98 327.6 0.0 8.4e-98 326.9 0.0 1.3 1 0 0 1 1 1 1 Band 3 cytoplasmic domain PTS_EIIA_2 PF00359.17 KFM01687.1 - 8.7e-06 25.5 0.0 0.00021 21.0 0.0 2.3 2 0 0 2 2 2 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Serum_albumin PF00273.15 KFM01688.1 - 1.7e-74 249.1 17.8 3.6e-41 140.5 0.8 3.0 3 0 0 3 3 3 3 Serum albumin family VitD-bind_III PF09164.5 KFM01688.1 - 1.1e-32 111.3 22.3 2.5e-28 97.4 0.5 5.7 5 1 1 6 6 6 3 Vitamin D binding protein, domain III DegS PF05384.6 KFM01688.1 - 0.02 14.0 0.0 0.05 12.8 0.0 1.6 1 0 0 1 1 1 0 Sensor protein DegS CSD PF00313.17 KFM01689.1 - 2.4e-15 56.0 0.2 4.2e-15 55.2 0.1 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain PMP22_Claudin PF00822.15 KFM01690.1 - 2.7e-16 59.6 6.3 3.2e-16 59.4 4.4 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFM01690.1 - 1.8e-12 47.2 4.4 2.7e-12 46.7 2.9 1.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HGMIC_fpl PF10242.4 KFM01690.1 - 0.017 15.1 4.9 0.035 14.1 3.4 1.6 1 1 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein PIRT PF15099.1 KFM01690.1 - 0.04 13.1 0.8 0.2 10.8 0.1 2.1 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family PMP22_Claudin PF00822.15 KFM01691.1 - 7.2e-24 84.3 3.1 8.3e-24 84.1 2.1 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFM01691.1 - 6.3e-10 39.0 6.6 8.2e-10 38.6 4.6 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 KFM01691.1 - 0.018 14.6 2.5 0.014 14.9 1.0 1.4 1 1 0 1 1 1 0 Amastin surface glycoprotein H_PPase PF03030.11 KFM01691.1 - 0.071 11.3 0.6 0.076 11.2 0.4 1.0 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase DUF204 PF02659.10 KFM01691.1 - 0.14 12.3 3.3 0.13 12.4 0.9 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF DUF1218 PF06749.7 KFM01691.1 - 0.14 12.6 3.8 2.3 8.7 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) CD20 PF04103.10 KFM01691.1 - 0.79 9.6 9.3 4.1 7.3 6.6 2.3 1 1 1 2 2 2 0 CD20-like family DUF4064 PF13273.1 KFM01691.1 - 5 7.2 7.2 18 5.5 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF2452 PF10504.4 KFM01692.1 - 4.3e-63 211.3 0.2 4.9e-63 211.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2452) Ras PF00071.17 KFM01693.1 - 3.7e-50 169.4 0.0 4.1e-50 169.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM01693.1 - 5.6e-16 59.1 0.0 1.2e-15 58.0 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFM01693.1 - 1.8e-06 27.3 0.0 2e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFM01693.1 - 0.03 14.2 0.0 0.22 11.4 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase ORC3_N PF07034.6 KFM01693.1 - 0.11 11.3 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus wnt PF00110.14 KFM01694.1 - 2.8e-127 424.2 25.1 3.1e-127 424.0 17.4 1.0 1 0 0 1 1 1 1 wnt family Pkinase_Tyr PF07714.12 KFM01695.1 - 6.4e-92 307.2 0.0 8.7e-92 306.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ephrin_lbd PF01404.14 KFM01695.1 - 4e-73 245.0 0.0 6.2e-73 244.3 0.0 1.3 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase PF00069.20 KFM01695.1 - 4e-45 153.9 0.0 5.9e-45 153.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.16 KFM01695.1 - 4e-32 110.1 0.2 5.7e-16 58.4 0.1 2.9 3 0 0 3 3 3 2 Fibronectin type III domain EphA2_TM PF14575.1 KFM01695.1 - 6.9e-26 90.4 0.0 1.3e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SAM_1 PF00536.25 KFM01695.1 - 4.4e-20 71.6 0.1 7.9e-20 70.7 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFM01695.1 - 3e-15 55.8 0.0 6.7e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) GCC2_GCC3 PF07699.8 KFM01695.1 - 0.00049 19.6 1.8 0.00049 19.6 1.2 2.5 2 0 0 2 2 2 1 GCC2 and GCC3 SusE PF14292.1 KFM01695.1 - 0.0011 18.7 0.0 0.33 10.7 0.1 2.3 2 0 0 2 2 2 1 SusE outer membrane protein Interfer-bind PF09294.5 KFM01695.1 - 0.0022 17.9 0.1 0.021 14.8 0.0 2.4 3 0 0 3 3 3 1 Interferon-alpha/beta receptor, fibronectin type III Kdo PF06293.9 KFM01695.1 - 0.018 14.1 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family C1q PF00386.16 KFM01696.1 - 1.7e-33 115.3 0.0 2.1e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 KFM01696.1 - 7.9e-13 47.7 37.1 1.5e-08 34.0 15.6 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) TNF PF00229.13 KFM01696.1 - 0.0036 16.8 0.3 0.13 11.7 0.2 2.1 1 1 0 1 1 1 1 TNF(Tumour Necrosis Factor) family Collagen PF01391.13 KFM01697.1 - 4.6e-19 67.7 54.1 4.6e-11 42.0 15.5 2.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) C1q PF00386.16 KFM01697.1 - 4.2e-16 59.0 0.1 5.1e-16 58.8 0.1 1.1 1 0 0 1 1 1 1 C1q domain Pkinase_Tyr PF07714.12 KFM01698.1 - 4.1e-98 327.5 0.0 4.7e-98 327.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM01698.1 - 2.7e-49 167.6 0.0 3.2e-49 167.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.1 KFM01698.1 - 3.6e-14 52.8 1.2 6.4e-14 52.1 0.8 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Kdo PF06293.9 KFM01698.1 - 0.075 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Beta-lactamase PF00144.19 KFM01699.1 - 2.1e-38 132.2 0.0 3.1e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase CRAL_TRIO_N PF03765.10 KFM01700.1 - 1e-09 38.3 0.8 1.7e-09 37.6 0.0 1.8 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO PF00650.15 KFM01700.1 - 1.9e-09 37.2 0.0 3.2e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain Ras PF00071.17 KFM01701.1 - 5.9e-57 191.5 0.0 6.8e-57 191.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM01701.1 - 1.9e-16 60.6 0.0 3.4e-16 59.7 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFM01701.1 - 6.3e-12 45.0 0.0 7e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFM01701.1 - 0.00029 20.0 0.0 0.00029 20.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFM01701.1 - 0.00051 19.5 0.0 0.00062 19.2 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Rbsn PF11464.3 KFM01701.1 - 0.052 13.1 0.0 13 5.4 0.0 2.4 2 0 0 2 2 2 0 Rabenosyn Rab binding domain Carb_anhydrase PF00194.16 KFM01702.1 - 8.7e-97 323.0 0.0 9.7e-97 322.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase PDZ PF00595.19 KFM01705.1 - 2.1e-20 72.6 2.6 2e-12 47.0 0.1 2.8 3 0 0 3 3 3 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM01705.1 - 8.5e-11 41.5 0.3 3.1e-06 26.9 0.0 2.4 2 0 0 2 2 2 2 PDZ domain SEP PF08059.8 KFM01706.1 - 9.2e-30 102.7 0.6 1.7e-29 101.9 0.1 1.7 2 0 0 2 2 2 1 SEP domain UBX PF00789.15 KFM01706.1 - 2.4e-18 65.9 0.2 3.8e-18 65.3 0.1 1.3 1 0 0 1 1 1 1 UBX domain Spt20 PF12090.3 KFM01706.1 - 0.0022 17.3 0.0 0.0034 16.7 0.0 1.5 1 1 0 1 1 1 1 Spt20 family FAM110_N PF14161.1 KFM01707.1 - 2.3e-52 175.8 4.9 2.3e-52 175.8 3.4 2.1 2 0 0 2 2 2 1 Centrosome-associated N terminus FAM110_C PF14160.1 KFM01707.1 - 2.4e-47 160.5 1.5 2.4e-47 160.5 1.1 2.2 3 0 0 3 3 3 1 Centrosome-associated C terminus Inositol_P PF00459.20 KFM01708.1 - 2.1e-35 122.3 0.2 2.4e-35 122.1 0.2 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family RuvA_N PF01330.16 KFM01708.1 - 0.12 12.1 0.1 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 RuvA N terminal domain Opiods_neuropep PF01160.13 KFM01709.1 - 1e-10 41.2 3.3 1.5e-10 40.6 2.3 1.3 1 0 0 1 1 1 1 Vertebrate endogenous opioids neuropeptide Op_neuropeptide PF08035.6 KFM01709.1 - 1.4e-07 30.9 38.1 0.01 15.3 0.3 7.3 7 0 0 7 7 7 7 Opioids neuropeptide adh_short PF00106.20 KFM01710.1 - 4.1e-29 101.6 0.0 5.1e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFM01710.1 - 3.2e-13 50.0 0.0 4.1e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFM01710.1 - 4e-11 42.8 0.0 5.9e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KFM01711.1 - 1.6e-29 102.9 0.1 1.9e-29 102.7 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFM01711.1 - 2.9e-11 43.6 0.1 3.5e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFM01711.1 - 5.4e-11 42.4 0.1 7.7e-11 41.9 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFM01711.1 - 6.3e-05 22.5 0.0 9.3e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1903 PF08991.5 KFM01712.1 - 0.00037 20.6 0.5 0.00042 20.4 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CEP1-DNA_bind PF09287.5 KFM01712.1 - 0.0077 15.6 0.2 0.0093 15.4 0.1 1.1 1 0 0 1 1 1 1 CEP-1, DNA binding COX6B PF02297.12 KFM01712.1 - 0.042 13.8 6.2 0.03 14.3 3.5 1.4 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb CHCH PF06747.8 KFM01712.1 - 0.11 12.4 4.2 0.16 11.9 2.9 1.3 1 0 0 1 1 1 0 CHCH domain zf-RING_4 PF14570.1 KFM01712.1 - 1.4 8.5 4.7 5.5 6.6 1.7 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-H2C2_2 PF13465.1 KFM01713.1 - 3.1e-28 96.6 57.8 2.6e-05 24.3 0.7 8.5 8 0 0 8 8 8 8 Zinc-finger double domain zf-C2H2 PF00096.21 KFM01713.1 - 3.6e-23 80.4 64.6 0.00018 21.6 1.0 7.5 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM01713.1 - 2.3e-20 71.3 54.2 0.00052 20.1 1.7 7.6 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM01713.1 - 2e-07 30.9 46.2 0.04 14.0 1.0 7.2 7 1 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFM01713.1 - 9.8e-06 25.2 31.9 0.0015 18.3 0.1 6.7 6 0 0 6 6 6 2 C2H2-type zinc finger zf-met PF12874.2 KFM01713.1 - 0.0002 21.4 28.0 0.59 10.4 0.3 5.9 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KFM01713.1 - 0.038 14.1 40.5 0.79 9.8 1.1 5.5 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 KFM01713.1 - 3.1 8.0 37.1 0.34 11.0 0.3 5.2 2 1 4 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding PyrI_C PF02748.10 KFM01713.1 - 4.8 6.7 23.7 0.3 10.5 1.3 5.4 4 2 2 6 6 6 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Pkinase PF00069.20 KFM01714.1 - 1.6e-55 188.0 0.0 1.9e-55 187.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM01714.1 - 1.9e-41 141.8 0.0 2.3e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM01714.1 - 0.0014 17.6 0.0 0.0024 16.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF2059 PF09832.4 KFM01714.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2059) Kdo PF06293.9 KFM01714.1 - 0.17 10.8 0.1 0.68 8.9 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_S10 PF00338.17 KFM01715.1 - 5.4e-34 115.9 0.4 6.3e-34 115.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Pkinase_Tyr PF07714.12 KFM01716.1 - 3.3e-97 324.6 0.0 4.2e-97 324.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM01716.1 - 3.9e-50 170.4 0.0 5.7e-50 169.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 KFM01716.1 - 1.6e-24 85.5 0.0 3.3e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.23 KFM01716.1 - 4e-17 61.3 0.1 9.3e-17 60.1 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFM01716.1 - 1.7e-11 43.4 0.1 4.4e-11 42.1 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFM01716.1 - 1.5e-09 37.1 0.5 4.2e-09 35.7 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain Methyltransf_15 PF09445.5 KFM01717.1 - 1.5e-43 148.2 0.1 2.5e-43 147.4 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.13 KFM01717.1 - 1.4e-10 41.0 0.0 3.7e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.2 KFM01717.1 - 2.9e-10 40.7 0.0 7.3e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFM01717.1 - 4.4e-10 39.6 0.0 9.5e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFM01717.1 - 7.9e-08 32.0 0.4 2.5e-07 30.3 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.11 KFM01717.1 - 2e-07 30.8 0.0 4.4e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.1 KFM01717.1 - 3e-06 27.5 0.1 1.3e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFM01717.1 - 6.7e-05 23.2 0.1 0.00021 21.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 KFM01717.1 - 0.00049 19.6 0.1 0.00049 19.6 0.1 2.6 2 1 0 2 2 1 1 DNA methylase ADH_zinc_N PF00107.21 KFM01717.1 - 0.0012 18.3 0.0 0.0025 17.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PrmA PF06325.8 KFM01717.1 - 0.0065 15.6 0.2 0.017 14.2 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_3 PF01596.12 KFM01717.1 - 0.01 14.8 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Acyltransferase PF01553.16 KFM01718.1 - 4.5e-08 32.6 0.0 6.8e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DAGAT PF03982.8 KFM01718.1 - 1.7e-06 27.0 0.0 2e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.16 KFM01719.1 - 1.9e-08 33.8 0.0 8.5e-08 31.7 0.0 2.0 1 1 0 1 1 1 1 Acyltransferase DAGAT PF03982.8 KFM01719.1 - 3.2e-05 22.7 0.0 6e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol acyltransferase XK-related PF09815.4 KFM01720.1 - 1.3e-105 353.0 24.3 1.5e-105 352.8 16.8 1.0 1 0 0 1 1 1 1 XK-related protein PLAT PF01477.18 KFM01722.1 - 1.9e-17 63.6 0.0 3.3e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 PLAT/LH2 domain DCX PF03607.12 KFM01723.1 - 6e-39 131.4 0.0 8.3e-22 76.5 0.0 2.8 2 0 0 2 2 2 2 Doublecortin Ribosomal_L18e PF00828.14 KFM01724.1 - 6.4e-13 49.2 0.4 2.5e-12 47.3 0.3 1.9 1 1 0 1 1 1 1 Ribosomal protein L18e/L15 Abhydrolase_2 PF02230.11 KFM01725.1 - 5.3e-71 238.4 0.0 5.9e-71 238.3 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KFM01725.1 - 3.1e-10 39.9 0.0 3.7e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFM01725.1 - 3.4e-07 30.3 0.0 6.5e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KFM01725.1 - 3.4e-06 26.8 0.0 5.1e-05 22.9 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 KFM01725.1 - 4.1e-05 23.2 0.0 4.5e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cutinase PF01083.17 KFM01725.1 - 0.00065 19.4 0.0 0.0013 18.4 0.0 1.4 1 1 0 1 1 1 1 Cutinase Peptidase_S9 PF00326.16 KFM01725.1 - 0.0015 17.7 0.0 0.78 8.9 0.0 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family DUF2974 PF11187.3 KFM01725.1 - 0.0019 17.5 0.0 0.0026 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) DLH PF01738.13 KFM01725.1 - 0.023 14.0 0.0 0.03 13.5 0.0 1.1 1 0 0 1 1 1 0 Dienelactone hydrolase family FSH1 PF03959.8 KFM01725.1 - 0.031 13.7 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Lipase_3 PF01764.20 KFM01725.1 - 0.033 13.8 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Esterase PF00756.15 KFM01725.1 - 0.052 12.9 0.0 0.061 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative esterase AXE1 PF05448.7 KFM01725.1 - 0.16 10.4 0.0 0.24 9.8 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) TFIIS_M PF07500.9 KFM01726.1 - 5.9e-41 139.1 3.1 5.9e-41 139.1 2.2 1.9 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 KFM01726.1 - 2e-19 68.9 8.2 4.4e-19 67.8 5.7 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 KFM01726.1 - 2.2e-12 46.2 0.2 7.3e-12 44.6 0.1 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain tRNA_synt_1c_R2 PF04557.10 KFM01726.1 - 0.39 11.4 6.7 0.11 13.2 1.2 2.3 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Baculo_LEF5_C PF11792.3 KFM01726.1 - 0.4 10.1 2.6 1.3 8.4 1.8 1.9 1 1 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain TF_Zn_Ribbon PF08271.7 KFM01726.1 - 0.82 9.0 6.3 0.47 9.8 2.5 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding DUF4355 PF14265.1 KFM01726.1 - 1.7 8.5 15.5 0.22 11.4 1.3 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4355) RGS PF00615.14 KFM01727.1 - 1.1e-34 119.1 1.3 1.4e-34 118.6 0.9 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain V-ATPase_H_N PF03224.9 KFM01728.1 - 8.5e-104 347.0 6.0 8.5e-104 347.0 4.1 1.3 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 KFM01728.1 - 2.4e-30 104.8 0.1 2.4e-30 104.8 0.0 2.7 3 1 0 3 3 3 1 V-ATPase subunit H Arm PF00514.18 KFM01728.1 - 2.8e-06 26.9 0.5 0.0031 17.2 0.0 4.0 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat UCH PF00443.24 KFM01728.1 - 0.0017 17.5 1.1 0.0023 17.1 0.1 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Adaptin_N PF01602.15 KFM01728.1 - 0.0022 16.4 1.2 0.034 12.4 0.0 2.7 3 0 0 3 3 3 1 Adaptin N terminal region DUF3826 PF12875.2 KFM01728.1 - 0.0038 16.9 0.6 0.0087 15.7 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3826) YlbD_coat PF14071.1 KFM01728.1 - 0.0057 16.7 1.0 0.0057 16.7 0.7 2.1 2 0 0 2 2 2 1 Putative coat protein DUF2326 PF10088.4 KFM01728.1 - 0.11 12.0 0.1 0.11 12.0 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2326) 7tm_1 PF00001.16 KFM01729.1 - 1.1e-63 214.7 21.7 1.3e-63 214.5 15.0 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 KFM01729.1 - 1.2e-08 34.4 15.6 1.6e-08 34.0 10.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.4 KFM01729.1 - 1.3e-07 31.0 21.1 1.6e-07 30.7 14.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Fumarate_red_D PF02313.12 KFM01729.1 - 0.013 15.4 1.6 0.035 13.9 1.1 1.7 1 0 0 1 1 1 0 Fumarate reductase subunit D Herpes_US9 PF06072.6 KFM01729.1 - 0.1 12.4 0.2 0.1 12.4 0.1 2.8 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 7TM_GPCR_Str PF10326.4 KFM01729.1 - 0.12 11.4 14.7 0.24 10.4 2.6 2.4 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Str DUF3810 PF12725.2 KFM01729.1 - 1.1 8.1 4.0 2 7.2 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) E1-E2_ATPase PF00122.15 KFM01729.1 - 3.8 6.4 7.2 2.4 7.1 0.3 2.2 1 1 1 2 2 2 0 E1-E2 ATPase ATG11 PF10377.4 KFM01730.1 - 2.3e-27 95.4 0.0 2.3e-27 95.4 0.0 4.0 3 1 0 3 3 3 1 Autophagy-related protein 11 MYT1 PF08474.6 KFM01731.1 - 2.1e-97 325.6 9.5 2.1e-97 325.6 6.6 2.3 2 0 0 2 2 2 1 Myelin transcription factor 1 zf-C2HC PF01530.13 KFM01731.1 - 2.2e-91 299.1 66.7 4.7e-17 61.4 3.3 6.5 6 0 0 6 6 6 6 Zinc finger, C2HC type DUF1664 PF07889.7 KFM01731.1 - 0.0027 17.5 0.2 0.0071 16.1 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) ADIP PF11559.3 KFM01731.1 - 0.087 12.7 8.6 0.035 14.0 3.2 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Sina PF03145.11 KFM01731.1 - 0.12 12.0 2.9 0.77 9.3 0.4 2.6 2 0 0 2 2 2 0 Seven in absentia protein family IBR PF01485.16 KFM01731.1 - 0.22 11.4 14.5 43 4.0 0.0 6.2 4 2 1 5 5 5 0 IBR domain Syntaxin-6_N PF09177.6 KFM01731.1 - 1.1 9.6 9.2 36 4.8 0.1 3.6 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DivIC PF04977.10 KFM01731.1 - 3.6 7.1 7.8 2.5 7.6 3.0 2.3 1 1 1 2 2 2 0 Septum formation initiator DUF972 PF06156.8 KFM01731.1 - 7.2 7.0 15.3 0.036 14.4 2.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF972) PCMT PF01135.14 KFM01732.1 - 1.3e-28 99.9 0.0 1.8e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SOCS_box PF07525.11 KFM01732.1 - 1.7e-06 27.7 3.1 0.003 17.3 0.7 2.7 2 0 0 2 2 2 2 SOCS box DOT1 PF08123.8 KFM01732.1 - 0.00011 21.6 0.0 0.00017 20.9 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 KFM01732.1 - 0.00027 21.4 0.0 0.00054 20.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFM01732.1 - 0.00037 20.0 0.0 0.00064 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.5 KFM01732.1 - 0.0045 16.5 0.0 0.011 15.2 0.0 1.5 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_12 PF08242.7 KFM01732.1 - 0.031 14.7 0.0 0.071 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PDZ PF00595.19 KFM01733.1 - 9.6e-17 60.9 0.5 1.7e-16 60.1 0.4 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PH PF00169.24 KFM01733.1 - 2.7e-05 24.3 0.3 0.016 15.3 0.2 2.7 2 1 0 2 2 2 2 PH domain PDZ_2 PF13180.1 KFM01733.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 PDZ domain Marek_SORF3 PF07153.6 KFM01733.1 - 0.069 11.8 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Marek's disease-like virus SORF3 protein Tricorn_PDZ PF14685.1 KFM01733.1 - 0.096 12.4 0.1 0.47 10.2 0.0 2.2 2 0 0 2 2 2 0 Tricorn protease PDZ domain Calsarcin PF05556.6 KFM01734.1 - 9.9e-85 284.0 0.4 1.2e-84 283.7 0.3 1.0 1 0 0 1 1 1 1 Calcineurin-binding protein (Calsarcin) UCH PF00443.24 KFM01735.1 - 2e-19 69.7 0.4 3.6e-19 68.9 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Lipocalin PF00061.18 KFM01736.1 - 1.1e-16 61.1 1.3 1.1e-16 61.0 0.9 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.1 KFM01736.1 - 2.7e-11 43.2 1.4 3.2e-11 43.0 1.0 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Propeptide_C1 PF08127.8 KFM01736.1 - 0.0057 16.2 0.5 0.012 15.1 0.1 1.7 2 0 0 2 2 2 1 Peptidase family C1 propeptide Lipocalin_4 PF13648.1 KFM01736.1 - 0.013 16.0 2.1 0.026 15.1 1.5 1.5 1 1 0 1 1 1 0 Lipocalin-like domain DUF3994 PF13159.1 KFM01736.1 - 0.038 14.2 0.6 0.052 13.8 0.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3994) PDEase_I PF00233.14 KFM01737.1 - 1.3e-69 234.5 1.0 1.3e-69 234.5 0.7 1.6 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.21 KFM01737.1 - 4.4e-42 143.8 0.0 1.9e-21 76.8 0.0 2.8 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.1 KFM01737.1 - 1.7e-14 53.9 0.0 6.6e-06 26.2 0.0 2.9 3 0 0 3 3 3 2 GAF domain GAF_2 PF13185.1 KFM01737.1 - 9.9e-14 52.0 0.0 9.1e-06 26.2 0.0 2.5 2 0 0 2 2 2 2 GAF domain Ribosomal_L30 PF00327.15 KFM01738.1 - 1e-13 50.5 1.5 1e-13 50.5 1.0 2.4 2 1 1 3 3 3 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.7 KFM01738.1 - 8.4e-09 35.3 0.2 8.4e-09 35.3 0.1 2.0 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L36e PF01158.13 KFM01738.1 - 0.12 12.3 0.7 0.71 9.8 0.1 2.3 2 1 0 2 2 2 0 Ribosomal protein L36e HORMA PF02301.13 KFM01739.1 - 8.3e-41 139.7 0.5 9.4e-41 139.5 0.3 1.0 1 0 0 1 1 1 1 HORMA domain ATG13 PF10033.4 KFM01739.1 - 0.022 14.2 0.1 0.036 13.5 0.1 1.3 1 0 0 1 1 1 0 Autophagy-related protein 13 zf-H2C2_2 PF13465.1 KFM01740.1 - 1e-80 262.3 115.6 1.6e-10 40.6 0.4 16.8 17 0 0 17 17 17 14 Zinc-finger double domain zf-C2H2 PF00096.21 KFM01740.1 - 1.6e-69 226.2 115.3 2.3e-06 27.6 0.4 16.2 16 0 0 16 16 16 16 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM01740.1 - 5.1e-57 186.0 101.6 0.00039 20.5 0.2 16.2 16 0 0 16 16 16 16 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM01740.1 - 6.5e-37 124.8 96.1 5.5e-06 26.3 0.7 16.1 16 0 0 16 16 16 12 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM01740.1 - 3e-31 106.6 92.8 3.2e-05 23.9 1.6 15.7 16 0 0 16 16 16 9 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFM01740.1 - 4.9e-23 80.2 86.7 0.0021 17.9 1.1 16.6 16 0 0 16 16 16 13 C2H2-type zinc finger zf-Di19 PF05605.7 KFM01740.1 - 9.9e-09 35.1 81.5 0.0066 16.5 1.5 9.9 5 2 2 9 9 9 6 Drought induced 19 protein (Di19), zinc-binding Trm112p PF03966.11 KFM01740.1 - 0.0009 19.5 12.9 0.08 13.3 0.3 5.6 3 3 1 4 4 4 1 Trm112p-like protein zf-C2H2_2 PF12756.2 KFM01740.1 - 0.002 18.2 92.8 0.53 10.4 1.7 13.5 1 1 11 13 13 12 4 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.1 KFM01740.1 - 0.01 16.0 4.7 0.074 13.3 0.3 15.4 16 1 0 16 16 16 0 C2H2-type zinc-finger domain zf-RING_3 PF14369.1 KFM01740.1 - 0.08 12.9 45.7 3.4 7.7 0.0 11.3 12 1 0 12 12 12 0 zinc-finger zf-CHCC PF10276.4 KFM01740.1 - 0.11 12.4 0.3 0.11 12.4 0.2 8.7 12 0 0 12 12 11 0 Zinc-finger domain zf-C2HC_2 PF13913.1 KFM01740.1 - 0.18 11.4 64.6 0.17 11.6 1.7 12.8 14 0 0 14 14 14 0 zinc-finger of a C2HC-type zf-CHY PF05495.7 KFM01740.1 - 0.33 11.1 88.8 0.12 12.5 3.6 8.2 2 2 7 9 9 8 0 CHY zinc finger BolA PF01722.13 KFM01740.1 - 1.8 8.6 18.3 10 6.1 0.0 6.7 4 3 2 6 6 6 0 BolA-like protein DUF2369 PF10179.4 KFM01741.1 - 2.1e-103 345.5 8.5 2.6e-94 315.6 4.6 2.1 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2369) fn3 PF00041.16 KFM01741.1 - 1.7e-09 37.6 1.3 0.0023 18.0 0.0 4.1 3 1 0 3 3 3 3 Fibronectin type III domain Mnd1 PF03962.10 KFM01742.1 - 3.4e-05 23.5 19.6 0.00051 19.7 0.2 2.6 2 1 0 2 2 2 2 Mnd1 family FlxA PF14282.1 KFM01742.1 - 0.0051 16.7 4.8 0.0051 16.7 3.3 3.0 2 1 1 3 3 3 2 FlxA-like protein NPV_P10 PF05531.7 KFM01742.1 - 0.016 15.4 2.9 1.2 9.4 0.1 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein KxDL PF10241.4 KFM01742.1 - 0.019 14.8 3.9 0.019 14.8 2.7 3.5 3 1 0 3 3 3 0 Uncharacterized conserved protein DUF4047 PF13256.1 KFM01742.1 - 0.022 14.7 4.3 0.022 14.7 3.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4047) GAS PF13851.1 KFM01742.1 - 0.29 10.2 36.5 0.56 9.3 14.9 2.4 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Sec34 PF04136.10 KFM01742.1 - 0.41 10.3 13.4 0.88 9.2 0.2 3.2 2 1 1 3 3 3 0 Sec34-like family DUF2968 PF11180.3 KFM01742.1 - 2.5 7.4 31.6 0.066 12.5 4.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2968) NusB PF01029.13 KFM01742.1 - 3.1 7.7 8.6 0.43 10.5 0.1 2.7 2 1 0 2 2 2 0 NusB family DUF4407 PF14362.1 KFM01742.1 - 5.1 5.9 17.0 76 2.1 11.9 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3166 PF11365.3 KFM01742.1 - 9.1 6.8 17.3 1.1 9.7 1.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3166) 7tm_1 PF00001.16 KFM01743.1 - 1.5e-57 194.7 21.2 1.9e-57 194.3 14.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM01743.1 - 3.2e-06 26.5 25.2 4.4e-06 26.0 17.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF4131 PF13567.1 KFM01743.1 - 0.081 12.3 0.2 0.081 12.3 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) 7TM_GPCR_Srw PF10324.4 KFM01743.1 - 0.41 9.7 27.1 2.7 7.0 18.8 2.2 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Herpes_US9 PF06072.6 KFM01743.1 - 5.2 6.9 6.8 1.1 9.1 0.2 3.3 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 MFS_1 PF07690.11 KFM01743.1 - 7.4 5.1 21.5 0.0043 15.8 3.3 2.6 1 1 2 3 3 3 0 Major Facilitator Superfamily I-set PF07679.11 KFM01744.1 - 1.7e-47 159.2 0.0 1e-17 63.7 0.0 3.4 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM01744.1 - 2.5e-30 104.4 0.0 3.2e-12 46.3 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.20 KFM01744.1 - 6.1e-23 80.7 0.1 5.8e-10 39.1 0.0 4.3 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 KFM01744.1 - 1.5e-19 70.0 0.9 6e-07 29.3 0.0 4.6 2 2 1 3 3 3 3 Immunoglobulin V-set domain Ig_3 PF13927.1 KFM01744.1 - 2.2e-19 69.6 0.1 8e-07 29.4 0.0 4.4 3 2 0 3 3 3 3 Immunoglobulin domain C2-set_2 PF08205.7 KFM01744.1 - 1.5e-06 28.0 0.3 0.00088 19.1 0.0 3.1 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Receptor_2B4 PF11465.3 KFM01744.1 - 0.00047 20.0 0.0 2.8 7.9 0.0 3.2 3 0 0 3 3 3 1 Natural killer cell receptor 2B4 Herpes_gI PF01688.12 KFM01744.1 - 0.024 13.7 0.0 15 4.6 0.0 3.1 3 0 0 3 3 3 0 Alphaherpesvirus glycoprotein I V-set_CD47 PF08204.6 KFM01744.1 - 0.12 12.1 0.2 1.6 8.4 0.0 2.3 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain HLH PF00010.21 KFM01745.1 - 7.3e-06 25.5 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Glyco_transf_29 PF00777.13 KFM01747.1 - 2.3e-73 246.6 0.0 3.6e-73 246.0 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) RNA_pol_Rpb1_5 PF04998.12 KFM01748.1 - 3e-104 348.1 0.0 8.8e-104 346.6 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KFM01748.1 - 7e-64 214.7 0.0 2.7e-63 212.8 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 KFM01748.1 - 4.2e-39 133.8 0.0 1.5e-38 132.0 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 KFM01748.1 - 5.1e-24 84.0 0.0 3.8e-23 81.2 0.0 2.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.7 KFM01748.1 - 1.1e-17 64.3 1.7 1.1e-17 64.3 1.1 5.0 4 1 0 4 4 4 2 RNA polymerase Rpb1, domain 1 DUF4407 PF14362.1 KFM01748.1 - 0.11 11.3 4.1 0.23 10.4 2.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_L35p PF01632.14 KFM01749.1 - 1.3e-23 82.6 7.3 1.8e-23 82.1 5.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L35 PMSR PF01625.16 KFM01749.1 - 0.062 13.1 0.0 0.07 12.9 0.0 1.1 1 0 0 1 1 1 0 Peptide methionine sulfoxide reductase DUF3437 PF11919.3 KFM01749.1 - 0.13 12.0 0.1 0.22 11.2 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3437) TB2_DP1_HVA22 PF03134.14 KFM01750.1 - 2.3e-31 107.4 10.8 3.4e-31 106.8 7.5 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF2306 PF10067.4 KFM01750.1 - 0.03 14.4 0.1 0.059 13.4 0.1 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2306) Halogen_Hydrol PF10112.4 KFM01750.1 - 0.06 12.7 0.1 0.088 12.2 0.1 1.2 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Snf7 PF03357.16 KFM01751.1 - 3.1e-41 140.5 16.7 3.1e-41 140.5 11.6 1.3 2 0 0 2 2 2 1 Snf7 zf-ZPR1 PF03367.8 KFM01751.1 - 0.0057 15.8 0.9 0.0057 15.8 0.7 1.7 2 0 0 2 2 2 1 ZPR1 zinc-finger domain IF3_C PF00707.17 KFM01751.1 - 0.026 14.2 1.4 0.026 14.2 1.0 2.0 2 0 0 2 2 2 0 Translation initiation factor IF-3, C-terminal domain DUF3915 PF13054.1 KFM01751.1 - 0.046 13.6 0.1 0.079 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Cauli_AT PF03233.8 KFM01751.1 - 0.36 10.5 5.0 0.11 12.2 0.2 2.1 1 1 1 2 2 2 0 Aphid transmission protein PSD4 PF07631.6 KFM01751.1 - 0.5 10.7 2.9 1.1 9.5 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1592) DUF3818 PF12825.2 KFM01751.1 - 2.1 6.9 7.4 2.8 6.5 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) zf-RING_2 PF13639.1 KFM01752.1 - 1.4e-11 44.0 10.8 1.4e-11 44.0 7.5 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFM01752.1 - 4.2e-07 29.8 11.3 4.2e-07 29.8 7.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM01752.1 - 1.4e-05 24.6 7.8 3.3e-05 23.4 5.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM01752.1 - 1.6e-05 24.4 8.0 1.6e-05 24.4 5.6 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 KFM01752.1 - 3.3e-05 23.9 11.2 8.3e-05 22.6 7.8 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KFM01752.1 - 0.00044 19.8 12.7 0.001 18.7 8.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFM01752.1 - 0.0038 17.0 8.3 0.0088 15.8 5.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KFM01752.1 - 0.096 12.4 5.3 0.11 12.2 2.3 2.1 1 1 1 2 2 2 0 RING-type zinc-finger CLTH PF10607.4 KFM01753.1 - 7.8e-31 106.7 0.0 2.3e-30 105.2 0.0 1.8 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 KFM01753.1 - 1.8e-18 65.9 1.9 4.2e-18 64.7 0.7 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.1 KFM01753.1 - 9.5e-05 22.1 0.2 0.00025 20.8 0.1 1.8 1 0 0 1 1 1 1 Ring finger domain zf-Nse PF11789.3 KFM01753.1 - 0.0082 15.6 1.2 0.019 14.5 0.9 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SnoaL_4 PF13577.1 KFM01753.1 - 0.026 14.4 0.0 0.26 11.1 0.0 2.2 2 0 0 2 2 2 0 SnoaL-like domain zf-C3HC4_2 PF13923.1 KFM01753.1 - 0.11 12.5 0.1 0.11 12.5 0.1 2.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM01753.1 - 0.76 9.5 4.2 0.28 10.9 0.8 1.9 2 0 0 2 2 2 0 zinc-RING finger domain V-set PF07686.12 KFM01754.1 - 3.2e-09 36.6 0.0 5e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 KFM01754.1 - 0.0035 17.4 0.1 0.27 11.3 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.11 KFM01754.1 - 0.036 13.9 0.0 0.098 12.5 0.0 1.8 1 1 1 2 2 2 0 Immunoglobulin I-set domain DUF1070 PF06376.7 KFM01754.1 - 1.8 8.5 3.8 5.6 6.9 2.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1070) V-set PF07686.12 KFM01755.1 - 5.9e-17 61.6 0.2 7.5e-17 61.2 0.2 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 KFM01755.1 - 1.5e-10 40.9 1.1 1.5e-09 37.8 0.7 2.1 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 KFM01755.1 - 0.00028 20.9 0.1 0.00053 20.0 0.1 1.5 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 KFM01755.1 - 0.00042 20.1 0.0 0.00074 19.3 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.1 KFM01755.1 - 0.0057 17.1 3.2 0.016 15.6 2.2 1.9 1 1 0 1 1 1 1 Immunoglobulin domain zf-met PF12874.2 KFM01756.1 - 2.9e-30 103.5 19.6 8.3e-08 32.1 0.1 4.3 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFM01756.1 - 4.8e-18 64.7 17.1 0.00033 20.6 0.2 4.4 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.7 KFM01756.1 - 8.4e-09 34.8 16.3 0.0023 17.4 1.0 4.4 4 0 0 4 4 4 4 U1 zinc finger zf-C2H2_2 PF12756.2 KFM01756.1 - 8.1e-05 22.6 13.1 0.53 10.4 0.1 4.1 1 1 1 4 4 4 3 C2H2 type zinc-finger (2 copies) DUF2248 PF10005.4 KFM01756.1 - 0.01 14.7 4.9 0.022 13.6 3.2 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2248) DUF2946 PF11162.3 KFM01756.1 - 0.075 13.2 2.3 9.8 6.4 0.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2946) zf-C2H2_4 PF13894.1 KFM01756.1 - 0.29 11.5 12.0 9.7 6.7 0.0 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf-DBF PF07535.7 KFM01756.1 - 0.39 10.4 8.1 11 5.7 0.1 3.8 4 0 0 4 4 4 0 DBF zinc finger SET PF00856.23 KFM01757.1 - 1.5e-09 38.3 1.9 7e-09 36.1 0.2 2.7 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.13 KFM01757.1 - 2.4e-09 36.9 17.5 2.4e-09 36.9 12.2 2.6 3 0 0 3 3 3 1 MYND finger TPR_12 PF13424.1 KFM01757.1 - 0.0015 18.4 0.1 0.006 16.4 0.0 1.9 1 1 1 2 2 2 2 Tetratricopeptide repeat Lipocalin_7 PF14651.1 KFM01758.1 - 1e-34 118.9 1.7 1.2e-34 118.8 1.2 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin PF00061.18 KFM01758.1 - 2.7e-15 56.6 1.6 3e-15 56.4 1.1 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Peptidase_C41 PF05417.6 KFM01758.1 - 0.068 12.7 0.0 0.099 12.1 0.0 1.3 1 0 0 1 1 1 0 Hepatitis E cysteine protease Thr_synth_N PF14821.1 KFM01759.1 - 2.1e-24 85.3 0.0 8.8e-24 83.3 0.0 2.2 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.20 KFM01759.1 - 7e-13 48.4 0.0 1.2e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Glyco_transf_56 PF07429.6 KFM01759.1 - 0.076 11.9 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 4-alpha-L-fucosyltransferase glycosyl transferase group 56 Vanabin-2 PF11437.3 KFM01759.1 - 0.28 11.1 2.7 0.47 10.4 1.8 1.3 1 0 0 1 1 1 0 Vanadium-binding protein 2 Fork_head PF00250.13 KFM01760.1 - 6.7e-43 144.6 0.1 1e-42 144.0 0.1 1.2 1 0 0 1 1 1 1 Fork head domain HNH_2 PF13391.1 KFM01760.1 - 0.064 13.0 0.1 0.23 11.2 0.0 1.9 2 0 0 2 2 2 0 HNH endonuclease 7tm_1 PF00001.16 KFM01762.1 - 3.8e-70 235.9 28.5 4.4e-70 235.7 19.8 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM01762.1 - 1.3e-08 34.3 33.5 9.7e-08 31.4 23.2 2.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM01762.1 - 1.1 8.2 33.6 2.6 7.0 22.1 2.2 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Pkinase PF00069.20 KFM01763.1 - 1.3e-50 172.0 0.0 4.4e-38 130.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFM01763.1 - 9.9e-32 110.0 0.0 1.7e-23 83.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase PQQ_2 PF13360.1 KFM01763.1 - 4.2e-06 26.4 0.1 0.0007 19.1 0.0 2.2 1 1 1 2 2 2 2 PQQ-like domain Kinase-like PF14531.1 KFM01763.1 - 4.6e-05 22.5 0.0 0.00011 21.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like PQQ PF01011.16 KFM01763.1 - 6.6e-05 22.2 0.0 0.26 10.8 0.0 3.4 3 0 0 3 3 3 2 PQQ enzyme repeat Kdo PF06293.9 KFM01763.1 - 0.013 14.5 0.1 0.035 13.1 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFM01763.1 - 0.017 14.8 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family PQQ_3 PF13570.1 KFM01763.1 - 0.058 13.6 0.6 5.7 7.3 0.0 3.6 4 0 0 4 4 4 0 PQQ-like domain Rib_5-P_isom_A PF06026.9 KFM01764.1 - 9.7e-66 220.3 0.0 1.2e-65 220.0 0.0 1.0 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Sugar-bind PF04198.8 KFM01764.1 - 0.043 12.7 0.1 0.061 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain Peptidase_C93 PF06035.6 KFM01764.1 - 0.083 12.3 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial transglutaminase-like cysteine proteinase BTLCP TBPIP_N PF15517.1 KFM01764.1 - 0.11 12.2 0.0 18 5.0 0.0 3.1 2 1 1 3 3 3 0 TBP-interacting protein N-terminus DeoRC PF00455.17 KFM01764.1 - 0.13 11.8 0.1 0.67 9.5 0.0 1.9 1 1 1 2 2 2 0 DeoR C terminal sensor domain CoA_binding PF02629.14 KFM01765.1 - 2.6e-31 107.9 1.7 1.6e-30 105.4 0.1 2.3 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 KFM01765.1 - 2e-23 82.6 0.1 3.4e-23 81.9 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 KFM01765.1 - 7.4e-09 35.3 0.0 1.4e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 KFM01765.1 - 2e-05 24.7 0.0 5.2e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 CoA binding domain Sema PF01403.14 KFM01766.1 - 3e-118 395.0 0.1 4.1e-118 394.6 0.1 1.2 1 0 0 1 1 1 1 Sema domain TSP_1 PF00090.14 KFM01766.1 - 8.1e-44 147.5 93.8 1.1e-11 44.6 5.7 7.5 7 0 0 7 7 7 5 Thrombospondin type 1 domain Sulfotransfer_1 PF00685.22 KFM01767.1 - 8.4e-26 90.8 0.3 1.1e-25 90.3 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 KFM01767.1 - 2.2e-06 28.6 0.0 6.2e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase family PsbM PF05151.7 KFM01767.1 - 0.019 14.5 0.8 0.033 13.7 0.5 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre M protein (PsbM) TM231 PF10149.4 KFM01768.1 - 1e-108 363.1 1.0 1.2e-108 362.9 0.7 1.0 1 0 0 1 1 1 1 Transmembrane protein 231 Atg8 PF02991.11 KFM01769.1 - 6.1e-41 138.6 0.1 6.7e-41 138.4 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 KFM01769.1 - 1.8e-06 28.0 0.0 2.1e-06 27.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 A_deamin PF02137.13 KFM01770.1 - 1.8e-114 382.6 0.1 3.9e-114 381.5 0.0 1.5 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain tRNA-synt_2 PF00152.15 KFM01771.1 - 2e-84 283.2 0.2 3.3e-84 282.5 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KFM01771.1 - 9.9e-16 57.3 0.1 3.3e-15 55.7 0.0 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KFM01771.1 - 6.8e-07 28.7 0.0 0.004 16.3 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 KFM01771.1 - 0.017 14.7 0.7 3.1 7.3 0.0 2.6 3 0 0 3 3 3 0 tRNA synthetase class II core domain (G, H, P, S and T) Dec-1 PF04624.9 KFM01771.1 - 0.11 12.1 0.4 0.24 11.0 0.3 1.5 1 0 0 1 1 1 0 Dec-1 repeat HSP70 PF00012.15 KFM01771.1 - 0.56 8.0 3.4 1 7.1 2.4 1.4 1 0 0 1 1 1 0 Hsp70 protein Rap1_C PF11626.3 KFM01772.1 - 3.8e-12 45.9 0.1 6.1e-12 45.2 0.1 1.3 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF2479 PF10651.4 KFM01772.1 - 0.033 13.6 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2479) Sulfotransfer_1 PF00685.22 KFM01773.1 - 5.7e-28 97.9 0.1 8.6e-28 97.3 0.1 1.3 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 KFM01773.1 - 5.5e-07 30.6 0.0 1.7e-06 29.0 0.0 1.8 1 1 0 1 1 1 1 Sulfotransferase family Aminotran_1_2 PF00155.16 KFM01774.1 - 5e-74 249.4 0.0 5.8e-74 249.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II TAT_ubiq PF07706.7 KFM01774.1 - 4.5e-10 39.2 0.6 7.3e-10 38.6 0.4 1.3 1 0 0 1 1 1 1 Aminotransferase ubiquitination site Beta_elim_lyase PF01212.16 KFM01774.1 - 2e-07 30.4 0.0 2.8e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KFM01774.1 - 1.2e-06 27.5 0.0 2.2e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KFM01774.1 - 5e-06 25.7 0.0 7.5e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 KFM01774.1 - 0.0065 14.8 0.0 0.0099 14.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_MocR PF12897.2 KFM01774.1 - 0.074 11.6 0.0 0.1 11.1 0.0 1.1 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase MARVEL PF01284.18 KFM01775.1 - 1.2e-07 31.6 4.7 1.7e-07 31.1 3.3 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF3784 PF12650.2 KFM01775.1 - 0.93 9.4 3.7 0.37 10.7 0.1 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3784) LRR_8 PF13855.1 KFM01777.1 - 7.4e-43 144.1 70.1 9.5e-11 41.2 3.0 9.0 7 2 1 8 8 8 8 Leucine rich repeat LRR_4 PF12799.2 KFM01777.1 - 5.7e-41 137.5 70.8 4.1e-08 32.6 0.5 13.0 3 3 10 15 15 15 14 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM01777.1 - 4e-33 108.3 67.8 0.033 14.1 0.0 19.9 19 1 2 21 21 21 14 Leucine Rich Repeat PP2C PF00481.16 KFM01777.1 - 9.8e-28 97.2 0.0 1.7e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_7 PF13504.1 KFM01777.1 - 2.9e-13 47.6 72.0 0.4 11.0 0.1 18.7 19 0 0 19 19 19 8 Leucine rich repeat LRR_6 PF13516.1 KFM01777.1 - 3.1e-05 23.5 59.2 0.54 10.4 0.1 16.1 17 2 2 19 19 19 4 Leucine Rich repeat Adaptin_N PF01602.15 KFM01778.1 - 1.2e-153 512.2 8.1 1.5e-153 511.9 5.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 KFM01778.1 - 2.1e-32 111.8 4.8 3.9e-32 110.9 3.3 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain CLASP_N PF12348.3 KFM01778.1 - 0.0097 15.2 0.6 0.089 12.1 0.1 2.6 2 0 0 2 2 2 1 CLASP N terminal AXH PF08517.7 KFM01779.1 - 1.5e-39 134.7 0.0 2.7e-39 133.8 0.0 1.4 1 0 0 1 1 1 1 Ataxin-1 and HBP1 module (AXH) Pap_E4 PF02711.9 KFM01779.1 - 2.7 8.8 9.2 0.37 11.6 2.8 2.3 2 0 0 2 2 2 0 E4 protein zf-met PF12874.2 KFM01780.1 - 5.4e-07 29.6 3.8 0.62 10.3 0.2 3.5 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 KFM01780.1 - 1.8e-05 24.7 0.6 0.39 11.1 0.0 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM01780.1 - 3.7e-05 23.7 10.9 0.11 12.9 0.6 3.9 4 0 0 4 4 3 2 C2H2-type zinc finger zf-Di19 PF05605.7 KFM01780.1 - 0.00075 19.5 1.6 0.00075 19.5 1.1 2.3 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 KFM01780.1 - 0.00077 19.5 0.1 16 5.7 0.0 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 KFM01780.1 - 0.0019 18.4 12.5 0.011 16.0 0.0 3.8 4 0 0 4 4 3 1 Zinc finger, C2H2 type DZR PF12773.2 KFM01780.1 - 0.029 14.1 2.7 0.061 13.1 0.6 2.5 2 1 0 2 2 2 0 Double zinc ribbon Rad50_zn_hook PF04423.9 KFM01780.1 - 0.048 13.1 5.3 0.17 11.3 0.0 3.5 2 1 0 3 3 3 0 Rad50 zinc hook motif RRN7 PF11781.3 KFM01780.1 - 0.35 10.4 2.6 9 5.8 0.1 3.3 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-ribbon_3 PF13248.1 KFM01780.1 - 0.62 9.3 3.4 0.77 9.0 0.3 2.6 2 1 0 2 2 2 0 zinc-ribbon domain CAF-1_p150 PF11600.3 KFM01780.1 - 0.62 9.3 25.0 0.014 14.7 11.4 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Peptidase_S46 PF10459.4 KFM01780.1 - 0.95 7.7 9.5 1.3 7.3 6.6 1.1 1 0 0 1 1 1 0 Peptidase S46 PhnA_Zn_Ribbon PF08274.7 KFM01780.1 - 4.5 7.1 13.2 12 5.7 0.1 3.8 3 1 0 3 3 3 0 PhnA Zinc-Ribbon Prok-RING_4 PF14447.1 KFM01780.1 - 4.6 6.8 5.6 35 4.0 0.0 3.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 Ist1 PF03398.9 KFM01782.1 - 1.3e-60 203.5 3.9 1.6e-60 203.2 2.7 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DHO_dh PF01180.16 KFM01783.1 - 2.2e-109 365.0 0.0 2.7e-109 364.7 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 KFM01783.1 - 0.007 15.2 0.6 0.021 13.7 0.4 1.7 1 1 0 1 1 1 1 FMN-dependent dehydrogenase PcrB PF01884.12 KFM01783.1 - 0.026 13.7 0.1 3.6 6.7 0.0 2.2 2 0 0 2 2 2 0 PcrB family NMO PF03060.10 KFM01783.1 - 0.027 13.6 0.1 0.057 12.5 0.0 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase OB_NTP_bind PF07717.11 KFM01784.1 - 1.4e-25 89.3 0.1 6e-25 87.2 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KFM01784.1 - 8.1e-25 86.8 2.6 2.5e-24 85.2 0.0 3.1 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KFM01784.1 - 3.5e-13 49.2 0.0 8e-13 48.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFM01784.1 - 1.1e-07 31.5 0.1 1e-06 28.3 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KFM01784.1 - 3.3e-06 27.2 0.0 8.9e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KFM01784.1 - 0.0015 17.4 0.0 0.0029 16.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.9 KFM01784.1 - 0.0025 17.5 0.0 0.0056 16.4 0.0 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain ResIII PF04851.10 KFM01784.1 - 0.003 17.4 0.3 1.7 8.4 0.0 3.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.11 KFM01784.1 - 0.019 14.1 0.0 0.046 12.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activ_2 PF14532.1 KFM01784.1 - 0.022 14.8 0.0 0.33 11.0 0.0 2.6 3 0 0 3 3 2 0 Sigma-54 interaction domain SRP54 PF00448.17 KFM01784.1 - 0.045 13.1 0.1 0.1 12.0 0.1 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain DUF243 PF03103.12 KFM01784.1 - 0.064 13.3 2.8 0.7 10.0 0.2 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF243) AAA_19 PF13245.1 KFM01784.1 - 0.17 11.6 0.0 0.43 10.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain DUF605 PF04652.11 KFM01784.1 - 1.6 8.0 15.1 2.8 7.2 10.5 1.4 1 0 0 1 1 1 0 Vta1 like Tropomyosin PF00261.15 KFM01785.1 - 0.0022 17.1 19.3 0.0031 16.6 13.3 1.2 1 0 0 1 1 1 1 Tropomyosin BicD PF09730.4 KFM01785.1 - 0.016 13.6 16.4 0.017 13.5 11.3 1.0 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D DUF551 PF04448.7 KFM01785.1 - 0.093 13.4 0.4 0.19 12.5 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF551) Golgin_A5 PF09787.4 KFM01785.1 - 0.096 11.1 21.1 0.12 10.9 14.6 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF1529 PF07485.6 KFM01785.1 - 0.13 11.9 1.8 5.5 6.7 0.1 2.1 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1259) TMF_TATA_bd PF12325.3 KFM01785.1 - 0.26 11.0 22.3 0.25 11.0 12.0 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Transformer PF06495.6 KFM01785.1 - 0.37 10.6 2.2 0.4 10.5 1.5 1.2 1 0 0 1 1 1 0 Fruit fly transformer protein APH PF01636.18 KFM01785.1 - 0.44 10.2 5.7 0.54 9.9 4.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family ATG16 PF08614.6 KFM01785.1 - 0.57 9.9 22.3 0.22 11.3 10.2 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) BRE1 PF08647.6 KFM01785.1 - 0.64 10.0 18.6 0.96 9.4 10.0 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Macoilin PF09726.4 KFM01785.1 - 0.72 8.0 19.8 0.84 7.8 13.7 1.0 1 0 0 1 1 1 0 Transmembrane protein CENP-F_leu_zip PF10473.4 KFM01785.1 - 0.75 9.6 24.6 0.98 9.2 17.0 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CENP-Q PF13094.1 KFM01785.1 - 1 9.3 21.8 1.5 8.7 15.1 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Atg14 PF10186.4 KFM01785.1 - 1.6 7.6 23.5 1.9 7.3 16.3 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Allexi_40kDa PF05549.6 KFM01785.1 - 1.8 7.7 6.5 1.5 8.0 3.8 1.4 1 1 0 1 1 1 0 Allexivirus 40kDa protein HlyD PF00529.15 KFM01785.1 - 1.9 7.7 19.9 2.5 7.3 13.8 1.0 1 0 0 1 1 1 0 HlyD family secretion protein UPF0158 PF03682.8 KFM01785.1 - 1.9 8.0 11.6 30 4.2 8.0 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0158) TMCO5 PF14992.1 KFM01785.1 - 2.3 7.3 17.4 2.7 7.0 12.1 1.0 1 0 0 1 1 1 0 TMCO5 family MT PF12777.2 KFM01785.1 - 2.4 6.8 7.4 0.71 8.5 2.2 1.8 1 1 1 2 2 2 0 Microtubule-binding stalk of dynein motor TBPIP PF07106.8 KFM01785.1 - 3.5 7.1 16.6 1.5 8.3 8.9 1.9 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Peptidase_S64 PF08192.6 KFM01785.1 - 5.4 5.2 8.8 5.9 5.1 6.1 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF3450 PF11932.3 KFM01785.1 - 6.3 5.9 20.5 7.7 5.6 14.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) APG6 PF04111.7 KFM01785.1 - 8.6 5.2 22.9 13 4.7 15.6 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 Microtub_assoc PF07989.6 KFM01785.1 - 8.7 6.2 14.4 4 7.3 0.8 2.8 2 1 1 3 3 3 0 Microtubule associated IncA PF04156.9 KFM01785.1 - 9.1 5.8 29.6 0.75 9.3 15.3 1.6 1 1 0 1 1 1 0 IncA protein CENP-H PF05837.7 KFM01786.1 - 1.3 9.2 4.6 3.5 7.8 0.1 2.2 2 1 0 2 2 2 0 Centromere protein H (CENP-H) ATG16 PF08614.6 KFM01786.1 - 3.3 7.4 9.0 4.5 7.0 6.3 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) MitMem_reg PF13012.1 KFM01787.1 - 4.8e-40 136.2 0.2 1.6e-39 134.5 0.3 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 KFM01787.1 - 5.9e-23 80.7 0.8 2.3e-22 78.8 0.0 2.2 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RNase_H2-Ydr279 PF09468.5 KFM01787.1 - 0.017 14.3 4.2 0.022 13.9 2.9 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) BSMAP PF12280.3 KFM01787.1 - 0.15 11.9 1.0 0.21 11.4 0.7 1.2 1 0 0 1 1 1 0 Brain specific membrane anchored protein OAD_gamma PF04277.8 KFM01787.1 - 0.26 11.6 1.5 0.63 10.4 1.1 1.7 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain YqfQ PF14181.1 KFM01787.1 - 1.5 8.8 8.8 2.4 8.1 6.1 1.3 1 0 0 1 1 1 0 YqfQ-like protein Bap31 PF05529.7 KFM01787.1 - 3.9 6.8 7.3 6.1 6.2 5.1 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like NOB1_Zn_bind PF08772.6 KFM01788.1 - 1.4e-30 104.8 0.1 2.3e-30 104.2 0.1 1.3 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like AF1Q PF15017.1 KFM01788.1 - 1.2e-25 89.2 7.4 1.9e-25 88.6 5.1 1.3 1 0 0 1 1 1 1 Drug resistance and apoptosis regulator Cys_rich_KTR PF14205.1 KFM01788.1 - 0.015 14.7 0.1 0.032 13.6 0.1 1.5 1 0 0 1 1 1 0 Cysteine-rich KTR zf-ribbon_3 PF13248.1 KFM01788.1 - 0.028 13.6 0.3 0.065 12.4 0.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Peptidase_C31 PF05410.8 KFM01788.1 - 0.044 13.6 0.0 0.21 11.4 0.0 1.9 2 0 0 2 2 2 0 Porcine arterivirus-type cysteine proteinase alpha zinc_ribbon_2 PF13240.1 KFM01788.1 - 0.046 13.2 0.4 0.11 12.0 0.3 1.6 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.2 KFM01788.1 - 0.058 13.2 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Double zinc ribbon DUF2890 PF11081.3 KFM01788.1 - 0.44 10.5 4.9 0.74 9.8 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Cyt-b5 PF00173.23 KFM01790.1 - 4.8e-13 48.7 0.0 6.4e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain EMP24_GP25L PF01105.19 KFM01791.1 - 2.2e-23 82.9 0.1 2.4e-23 82.8 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2892 PF11127.3 KFM01791.1 - 0.057 13.2 0.0 0.097 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) Dor1 PF04124.7 KFM01792.1 - 5.4e-106 353.8 0.0 6.6e-106 353.5 0.0 1.1 1 0 0 1 1 1 1 Dor1-like family Sec5 PF15469.1 KFM01792.1 - 0.024 14.3 0.7 0.034 13.8 0.0 1.5 2 0 0 2 2 2 0 Exocyst complex component Sec5 Utp13 PF08625.6 KFM01792.1 - 0.095 12.3 0.1 0.29 10.7 0.0 1.8 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain AAA PF00004.24 KFM01793.1 - 4.6e-05 23.6 0.0 0.00013 22.1 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 KFM01794.1 - 2.7e-31 108.5 0.0 2.9e-31 108.3 0.0 1.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFM01794.1 - 6e-08 32.9 0.1 1.6e-05 25.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KFM01794.1 - 1e-07 31.5 0.2 0.0019 17.6 0.0 2.0 1 1 1 2 2 2 2 AAA domain IstB_IS21 PF01695.12 KFM01794.1 - 7.6e-07 28.7 0.0 9.5e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 KFM01794.1 - 2.9e-06 28.0 0.0 4.3e-06 27.5 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KFM01794.1 - 3.2e-06 27.0 0.0 3.8e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KFM01794.1 - 5.2e-06 25.4 0.0 7.2e-06 24.9 0.0 1.4 1 1 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 KFM01794.1 - 6.1e-06 25.9 0.0 1.5e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KFM01794.1 - 6.2e-06 26.3 0.0 0.002 18.1 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 KFM01794.1 - 1.3e-05 24.3 0.0 1.5e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 KFM01794.1 - 2.1e-05 24.4 0.0 5e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KFM01794.1 - 7.5e-05 22.6 0.0 0.0001 22.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) NACHT PF05729.7 KFM01794.1 - 0.00025 20.7 0.0 0.032 13.8 0.0 2.0 1 1 1 2 2 2 1 NACHT domain DUF815 PF05673.8 KFM01794.1 - 0.00026 19.9 0.0 0.00031 19.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.1 KFM01794.1 - 0.00033 20.9 0.0 0.00047 20.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 KFM01794.1 - 0.00068 18.8 0.1 0.24 10.4 0.0 2.0 1 1 1 2 2 2 2 KaiC Arch_ATPase PF01637.13 KFM01794.1 - 0.00075 19.2 0.0 0.2 11.3 0.0 2.0 1 1 1 2 2 2 1 Archaeal ATPase Zeta_toxin PF06414.7 KFM01794.1 - 0.00076 18.6 0.0 0.0035 16.4 0.0 2.0 1 1 0 1 1 1 1 Zeta toxin RNA_helicase PF00910.17 KFM01794.1 - 0.0011 19.1 0.0 0.0015 18.6 0.0 1.5 1 1 0 1 1 1 1 RNA helicase PhoH PF02562.11 KFM01794.1 - 0.0022 17.2 0.1 0.0024 17.1 0.1 1.4 1 1 0 1 1 1 1 PhoH-like protein Guanylate_kin PF00625.16 KFM01794.1 - 0.0023 17.4 0.0 0.027 13.9 0.0 2.0 1 1 0 2 2 2 1 Guanylate kinase Sigma54_activ_2 PF14532.1 KFM01794.1 - 0.0023 17.9 0.0 0.0038 17.2 0.0 1.4 1 1 0 1 1 1 1 Sigma-54 interaction domain ResIII PF04851.10 KFM01794.1 - 0.0029 17.4 0.0 0.0036 17.1 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Sigma54_activat PF00158.21 KFM01794.1 - 0.0035 16.8 0.0 0.019 14.4 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 KFM01794.1 - 0.0036 16.5 0.0 0.0061 15.7 0.0 1.5 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KFM01794.1 - 0.0066 16.1 0.0 0.0088 15.7 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain KAP_NTPase PF07693.9 KFM01794.1 - 0.0085 15.1 0.0 0.68 8.8 0.0 2.0 1 1 1 2 2 2 1 KAP family P-loop domain AAA_28 PF13521.1 KFM01794.1 - 0.011 15.7 0.0 0.018 15.0 0.0 1.5 1 1 1 2 2 2 0 AAA domain NB-ARC PF00931.17 KFM01794.1 - 0.012 14.5 0.0 0.014 14.3 0.0 1.0 1 0 0 1 1 1 0 NB-ARC domain AAA_21 PF13304.1 KFM01794.1 - 0.015 15.2 0.3 0.89 9.4 0.1 2.1 1 1 1 2 2 2 0 AAA domain MCM PF00493.18 KFM01794.1 - 0.018 13.8 0.0 0.037 12.8 0.0 1.4 2 0 0 2 2 2 0 MCM2/3/5 family AAA_24 PF13479.1 KFM01794.1 - 0.02 14.4 0.1 0.03 13.9 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KFM01794.1 - 0.026 13.9 0.1 0.23 10.8 0.0 1.9 1 1 1 2 2 2 0 AAA-like domain KTI12 PF08433.5 KFM01794.1 - 0.032 13.4 0.1 0.078 12.1 0.0 1.7 1 1 0 1 1 1 0 Chromatin associated protein KTI12 NTPase_1 PF03266.10 KFM01794.1 - 0.036 13.7 0.0 1.7 8.3 0.0 2.1 2 0 0 2 2 2 0 NTPase DUF2075 PF09848.4 KFM01794.1 - 0.036 13.0 0.0 0.11 11.5 0.0 1.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 KFM01794.1 - 0.039 13.5 0.0 0.071 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 KFM01794.1 - 0.04 13.4 0.0 0.047 13.1 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 KFM01794.1 - 0.042 14.1 0.0 0.059 13.6 0.0 1.3 1 1 0 1 1 1 0 ABC transporter Parvo_NS1 PF01057.12 KFM01794.1 - 0.056 12.3 0.0 0.08 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Oxidored_nitro PF00148.14 KFM01794.1 - 0.089 11.4 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Zot PF05707.7 KFM01794.1 - 0.13 11.7 0.2 1.6 8.1 0.1 2.0 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) Torsin PF06309.6 KFM01794.1 - 0.14 12.0 0.0 0.19 11.6 0.0 1.3 1 1 0 1 1 1 0 Torsin WD40 PF00400.27 KFM01795.1 - 6.7e-06 25.7 13.2 0.031 14.1 0.0 5.5 6 0 0 6 6 6 2 WD domain, G-beta repeat Chitin_synth_2 PF03142.10 KFM01796.1 - 3.7e-11 42.1 3.9 1.5e-05 23.6 0.0 3.3 2 1 1 3 3 3 3 Chitin synthase Glyco_tranf_2_3 PF13641.1 KFM01796.1 - 2.7e-10 40.4 0.3 9.9e-06 25.5 0.2 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KFM01796.1 - 0.00032 20.4 0.0 0.0009 18.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.1 KFM01796.1 - 0.0042 16.8 20.1 0.024 14.3 14.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 DUF2435 PF10363.4 KFM01797.1 - 4.2e-19 68.2 0.2 5.3e-18 64.7 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 KFM01797.1 - 7.1e-09 34.9 2.2 2.2e-08 33.4 1.5 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) HEAT PF02985.17 KFM01797.1 - 0.0038 17.1 0.4 0.66 10.2 0.0 3.9 3 0 0 3 3 3 1 HEAT repeat Cadherin PF00028.12 KFM01798.1 - 3e-59 197.2 5.6 3.5e-21 75.2 0.2 6.4 6 1 0 6 6 6 6 Cadherin domain Cadherin_C PF01049.12 KFM01798.1 - 1.9e-14 53.9 0.3 3.2e-14 53.2 0.2 1.4 1 0 0 1 1 1 1 Cadherin cytoplasmic region Big_3_3 PF13750.1 KFM01798.1 - 0.016 14.6 0.3 2.1 7.7 0.0 2.9 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) Transthyretin PF00576.16 KFM01799.1 - 2.5e-26 91.7 0.0 2.9e-26 91.5 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family GAS PF13851.1 KFM01800.1 - 7.4e-73 244.0 33.0 7.4e-73 244.0 22.8 3.1 1 1 2 3 3 3 1 Growth-arrest specific micro-tubule binding DUF4303 PF14136.1 KFM01800.1 - 0.26 10.9 17.5 0.26 10.8 1.4 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4303) Baculo_PEP_C PF04513.7 KFM01800.1 - 0.8 9.5 25.8 7 6.4 4.1 4.8 2 2 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 KFM01800.1 - 6.7 5.7 8.2 12 4.9 0.2 3.1 1 1 2 3 3 3 0 Reovirus sigma C capsid protein VWD PF00094.20 KFM01802.1 - 3.1e-27 95.6 0.3 5e-27 95.0 0.2 1.3 1 0 0 1 1 1 1 von Willebrand factor type D domain C8 PF08742.6 KFM01802.1 - 5.2e-18 65.0 11.8 1.1e-17 64.0 8.2 1.6 1 0 0 1 1 1 1 C8 domain zf-UDP PF14569.1 KFM01802.1 - 3.8 7.3 11.1 0.14 11.9 0.5 3.1 2 1 0 3 3 3 0 Zinc-binding RING-finger VWD PF00094.20 KFM01803.1 - 8.4e-29 100.7 2.8 8.4e-29 100.7 1.9 2.3 2 1 0 2 2 2 1 von Willebrand factor type D domain C8 PF08742.6 KFM01803.1 - 1.1e-21 76.8 14.1 1.1e-21 76.8 9.8 2.6 3 0 0 3 3 3 1 C8 domain Pacifastin_I PF05375.8 KFM01803.1 - 9.7e-07 28.2 7.4 9.7e-07 28.2 5.1 4.1 4 1 0 4 4 4 1 Pacifastin inhibitor (LCMII) TIL PF01826.12 KFM01803.1 - 0.0054 16.8 6.3 0.0054 16.8 4.3 4.7 4 1 0 4 4 4 1 Trypsin Inhibitor like cysteine rich domain VWD PF00094.20 KFM01804.1 - 3.8e-32 111.6 3.4 3.8e-32 111.6 2.3 2.5 3 0 0 3 3 3 1 von Willebrand factor type D domain C8 PF08742.6 KFM01804.1 - 8.6e-18 64.3 5.7 8.6e-18 64.3 3.9 4.3 3 0 0 3 3 3 1 C8 domain VWC PF00093.13 KFM01804.1 - 0.0026 17.8 15.1 0.0026 17.8 10.5 8.8 5 2 1 7 7 7 3 von Willebrand factor type C domain RecA PF00154.16 KFM01804.1 - 0.34 9.9 0.1 0.54 9.2 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein VWD PF00094.20 KFM01805.1 - 2.8e-26 92.5 0.4 2.8e-26 92.5 0.3 1.7 2 0 0 2 2 2 1 von Willebrand factor type D domain C8 PF08742.6 KFM01805.1 - 3.9e-22 78.2 10.1 3.9e-22 78.2 7.0 2.7 2 0 0 2 2 2 1 C8 domain VWC PF00093.13 KFM01805.1 - 1.3e-06 28.4 6.7 1.3e-06 28.4 4.7 3.9 3 1 1 4 4 4 1 von Willebrand factor type C domain TIL PF01826.12 KFM01805.1 - 2.4e-05 24.3 4.0 2.4e-05 24.3 2.7 4.7 3 1 0 3 3 3 1 Trypsin Inhibitor like cysteine rich domain Pacifastin_I PF05375.8 KFM01805.1 - 0.014 14.9 16.1 0.014 14.9 11.2 3.7 3 1 1 4 4 4 0 Pacifastin inhibitor (LCMII) VWD PF00094.20 KFM01806.1 - 3.2e-32 111.9 2.9 3.2e-32 111.9 2.0 2.0 2 1 0 2 2 2 1 von Willebrand factor type D domain C8 PF08742.6 KFM01806.1 - 4.3e-22 78.1 15.7 4.3e-22 78.1 10.9 2.1 2 0 0 2 2 2 1 C8 domain TIL PF01826.12 KFM01806.1 - 0.0031 17.5 5.3 0.0031 17.5 3.7 4.9 3 1 0 3 3 3 1 Trypsin Inhibitor like cysteine rich domain LRR_9 PF14580.1 KFM01807.1 - 2.1e-93 310.7 0.8 2.7e-93 310.3 0.6 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 KFM01807.1 - 3.2e-11 42.5 5.7 2.3e-05 23.8 1.5 2.8 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM01807.1 - 3.4e-07 29.9 12.4 3.4e-05 23.5 3.3 2.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 KFM01807.1 - 0.0017 18.1 4.6 5.4 7.4 0.1 4.2 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 KFM01807.1 - 0.11 12.8 4.8 20 5.9 0.1 3.9 4 0 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.1 KFM01807.1 - 0.36 11.0 8.4 3.3 8.0 0.4 4.2 3 1 1 4 4 4 0 Leucine Rich repeat Selenoprotein_S PF06936.6 KFM01808.1 - 8.5e-57 191.7 8.4 9.3e-57 191.6 5.8 1.0 1 0 0 1 1 1 1 Selenoprotein S (SelS) CCDC66 PF15236.1 KFM01808.1 - 0.41 10.2 13.1 0.52 9.9 9.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 66 CHGN PF05679.11 KFM01809.1 - 1.3e-188 627.7 0.4 1.5e-188 627.5 0.3 1.0 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.11 KFM01809.1 - 7.1e-14 51.6 0.0 1.2e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Fringe-like Glyco_transf_7C PF02709.9 KFM01809.1 - 5.4e-12 45.0 0.1 1.3e-11 43.7 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFM01809.1 - 1.3e-08 34.2 0.0 2.7e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Galactosyl_T PF01762.16 KFM01809.1 - 0.00019 21.0 0.1 0.0041 16.7 0.0 2.9 2 1 0 2 2 2 1 Galactosyltransferase Glyco_transf_21 PF13506.1 KFM01809.1 - 0.0038 16.5 0.0 0.04 13.1 0.0 2.5 2 1 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KFM01809.1 - 0.043 13.4 0.0 2.1 7.9 0.0 2.9 3 0 0 3 3 3 0 Glycosyl transferase family 2 WWE PF02825.15 KFM01809.1 - 0.34 10.3 2.0 3.5 7.1 0.0 3.1 4 0 0 4 4 4 0 WWE domain Pkinase PF00069.20 KFM01810.1 - 4.7e-43 147.2 0.0 8.6e-43 146.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM01810.1 - 3.7e-37 127.8 0.0 7.3e-37 126.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.2 KFM01810.1 - 2.6e-27 93.9 33.1 5.7e-06 25.8 0.7 7.8 5 2 2 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM01810.1 - 6.3e-26 89.9 27.5 9.6e-10 38.0 1.6 6.7 6 0 0 6 6 6 5 Leucine rich repeat LRR_1 PF00560.28 KFM01810.1 - 1.2e-15 55.1 27.9 1.3 9.3 0.1 11.5 12 0 0 12 12 10 6 Leucine Rich Repeat Ank_2 PF12796.2 KFM01810.1 - 1.2e-12 47.9 0.4 4.2e-09 36.6 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Miro PF08477.8 KFM01810.1 - 5.2e-10 39.8 0.0 1.5e-09 38.4 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein Ank PF00023.25 KFM01810.1 - 2.5e-09 36.4 2.1 0.064 13.0 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat LRR_7 PF13504.1 KFM01810.1 - 3.2e-09 35.4 26.3 0.19 12.0 0.1 11.1 11 0 0 11 11 10 1 Leucine rich repeat Ank_3 PF13606.1 KFM01810.1 - 6.2e-09 35.2 1.5 0.77 10.1 0.0 5.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 KFM01810.1 - 4.6e-07 29.8 3.9 1.6 9.1 0.0 4.9 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ras PF00071.17 KFM01810.1 - 2e-06 27.3 0.0 3.8e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Ras family Ank_4 PF13637.1 KFM01810.1 - 2.4e-06 27.8 0.5 0.044 14.3 0.0 3.1 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Arf PF00025.16 KFM01810.1 - 5.2e-06 25.8 0.0 1.1e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family LRR_6 PF13516.1 KFM01810.1 - 0.00011 21.8 21.8 0.029 14.4 0.1 9.2 10 0 0 10 10 9 1 Leucine Rich repeat MMR_HSR1 PF01926.18 KFM01810.1 - 0.0078 16.1 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFM01810.1 - 0.064 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region malic PF00390.14 KFM01810.1 - 0.18 11.4 0.2 11 5.5 0.0 2.3 2 0 0 2 2 2 0 Malic enzyme, N-terminal domain Aldedh PF00171.17 KFM01811.1 - 1e-188 627.3 0.0 1.2e-188 627.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KFM01811.1 - 0.00034 19.4 0.0 0.00077 18.2 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 KFM01811.1 - 0.0056 15.9 0.0 1.3 8.1 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) Ank PF00023.25 KFM01812.1 - 1.4e-50 166.6 1.5 1.5e-07 30.8 0.0 7.7 8 0 0 8 8 8 7 Ankyrin repeat Ank_2 PF12796.2 KFM01812.1 - 4.7e-48 161.4 0.0 1.9e-18 66.5 0.0 4.2 2 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFM01812.1 - 3.6e-45 151.5 5.6 8.1e-11 42.1 0.0 6.0 2 2 5 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM01812.1 - 1.5e-36 123.5 5.3 9e-08 32.1 0.1 7.0 1 1 6 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM01812.1 - 8.2e-28 93.6 1.3 1.1e-05 25.2 0.0 7.7 9 0 0 9 9 9 5 Ankyrin repeat SOCS_box PF07525.11 KFM01812.1 - 1.5e-13 50.3 1.6 4.2e-13 48.9 1.1 1.8 1 0 0 1 1 1 1 SOCS box Rubella_E2 PF05749.6 KFM01812.1 - 0.021 14.0 0.0 0.11 11.7 0.0 1.9 2 0 0 2 2 2 0 Rubella membrane glycoprotein E2 LINES_N PF14694.1 KFM01813.1 - 3.2e-108 361.9 9.2 3.2e-108 361.9 6.4 1.6 2 0 0 2 2 2 1 Lines N-terminus LINES_C PF14695.1 KFM01813.1 - 1.5e-18 65.7 0.7 3.8e-18 64.4 0.5 1.8 1 0 0 1 1 1 1 Lines C-terminus ADAM_spacer1 PF05986.9 KFM01814.1 - 2.9e-28 98.0 0.0 4.9e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Reprolysin PF01421.14 KFM01814.1 - 5e-24 85.0 0.6 3.7e-18 65.8 0.1 2.9 2 0 0 2 2 2 2 Reprolysin (M12B) family zinc metalloprotease TSP_1 PF00090.14 KFM01814.1 - 5.5e-24 84.0 88.2 5.6e-10 39.1 7.0 7.2 6 1 0 6 6 6 4 Thrombospondin type 1 domain Reprolysin_5 PF13688.1 KFM01814.1 - 2.3e-13 50.5 0.5 7.7e-13 48.8 0.3 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KFM01814.1 - 6e-10 39.7 0.0 1.5e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like PLAC PF08686.6 KFM01814.1 - 3.8e-09 36.6 15.4 4.8e-09 36.3 8.0 3.4 2 0 0 2 2 2 1 PLAC (protease and lacunin) domain Reprolysin_4 PF13583.1 KFM01814.1 - 2.6e-08 33.6 1.3 4e-07 29.7 0.9 2.3 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFM01814.1 - 5.1e-08 33.1 2.3 9.3e-08 32.3 0.5 2.3 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KFM01814.1 - 0.0015 18.2 0.1 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 Matrixin SRF-TF PF00319.13 KFM01815.1 - 1.4e-18 65.8 0.2 2.5e-18 65.0 0.2 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) HJURP_C PF12347.3 KFM01815.1 - 2.4e-05 23.8 0.0 2.4e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Holliday junction regulator protein family C-terminal repeat DUF2205 PF10224.4 KFM01818.1 - 0.0058 16.1 9.0 0.0058 16.1 6.3 6.2 6 2 0 6 6 6 2 Predicted coiled-coil protein (DUF2205) CopC PF04234.7 KFM01818.1 - 7.2 7.3 7.6 7.6 7.2 0.1 4.1 2 1 2 4 4 4 0 CopC domain zf-HC5HC2H_2 PF13832.1 KFM01819.1 - 1.1e-33 115.4 3.0 1.1e-33 115.4 2.1 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KFM01819.1 - 3.7e-28 97.4 2.2 3.7e-28 97.4 1.5 4.0 4 0 0 4 4 4 1 PHD-like zinc-binding domain EPL1 PF10513.4 KFM01819.1 - 7e-21 75.1 0.1 7e-21 75.1 0.1 3.5 3 2 0 3 3 3 1 Enhancer of polycomb-like PHD_2 PF13831.1 KFM01819.1 - 5.3e-13 48.0 6.3 5.3e-13 48.0 4.4 3.6 3 1 1 4 4 4 1 PHD-finger PHD PF00628.24 KFM01819.1 - 1.2e-11 44.0 23.3 1.2e-09 37.7 6.2 3.3 3 0 0 3 3 3 2 PHD-finger C1_1 PF00130.17 KFM01819.1 - 0.0026 17.4 3.8 0.0026 17.4 2.6 3.3 2 1 1 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.6 KFM01819.1 - 0.0063 16.4 2.8 0.0063 16.4 1.9 3.6 2 1 1 3 3 3 1 RING-like domain Prok-RING_1 PF14446.1 KFM01819.1 - 0.047 13.4 15.3 0.97 9.2 1.1 2.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 La PF05383.12 KFM01820.1 - 6.3e-23 80.3 0.1 1.4e-22 79.2 0.1 1.7 1 0 0 1 1 1 1 La domain API5 PF05918.6 KFM01820.1 - 5.3 5.4 8.7 8.6 4.7 6.0 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF2048 PF09752.4 KFM01821.1 - 4.4e-157 522.4 0.0 5.1e-157 522.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) Abhydrolase_6 PF12697.2 KFM01821.1 - 3.4e-06 27.0 0.0 4.6e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KFM01821.1 - 0.032 13.6 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.2 KFM01821.1 - 0.051 13.3 0.0 0.11 12.2 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family MFS_1 PF07690.11 KFM01822.1 - 6.2e-38 130.4 27.6 8.3e-31 106.9 11.6 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFM01822.1 - 6.9e-09 34.7 26.3 7.2e-09 34.7 7.5 3.3 3 0 0 3 3 3 3 Sugar (and other) transporter ESSS PF10183.4 KFM01822.1 - 1.1 9.7 2.8 36 4.8 0.1 2.8 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) HSP70 PF00012.15 KFM01823.1 - 1.6e-171 571.2 11.7 3.6e-163 543.7 0.2 2.9 2 1 1 3 3 3 3 Hsp70 protein MreB_Mbl PF06723.8 KFM01823.1 - 7.2e-09 34.6 0.0 1.2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Cadherin PF00028.12 KFM01824.1 - 0 2029.2 58.1 2.5e-24 85.3 0.4 34.6 34 1 0 34 34 34 34 Cadherin domain Cadherin_2 PF08266.7 KFM01824.1 - 7.5e-43 144.0 0.0 0.025 14.1 0.0 23.3 24 2 0 24 24 24 9 Cadherin-like Laminin_G_2 PF02210.19 KFM01824.1 - 1.4e-37 128.5 5.2 1.7e-19 70.1 0.0 3.7 4 0 0 4 4 4 2 Laminin G domain Laminin_G_1 PF00054.18 KFM01824.1 - 3.5e-30 104.7 0.1 1.4e-17 63.9 0.0 3.7 4 0 0 4 4 4 2 Laminin G domain EGF PF00008.22 KFM01824.1 - 1.5e-23 82.3 91.0 3.3e-07 30.1 6.0 7.2 6 1 0 6 6 6 6 EGF-like domain EGF_CA PF07645.10 KFM01824.1 - 1.8e-10 40.6 25.6 2.4e-07 30.6 4.5 7.5 5 2 2 7 7 7 2 Calcium-binding EGF domain EGF_3 PF12947.2 KFM01824.1 - 0.00082 19.2 1.1 0.00082 19.2 0.8 6.2 6 0 0 6 6 6 2 EGF domain hEGF PF12661.2 KFM01824.1 - 0.2 11.8 56.2 0.18 11.9 2.2 6.8 7 0 0 7 7 7 0 Human growth factor-like EGF EGF_2 PF07974.8 KFM01824.1 - 3.3 7.9 109.3 0.049 13.8 9.8 7.4 6 1 1 7 7 7 0 EGF-like domain Ank_2 PF12796.2 KFM01825.1 - 4.3e-148 482.0 43.7 1.6e-20 73.2 0.3 9.3 1 1 8 10 10 10 9 Ankyrin repeats (3 copies) Ank PF00023.25 KFM01825.1 - 6.1e-129 413.9 47.5 1.5e-08 33.9 0.1 19.5 19 0 0 19 19 19 19 Ankyrin repeat Ank_4 PF13637.1 KFM01825.1 - 2.9e-104 339.8 28.2 1.3e-10 41.4 0.0 15.0 3 2 12 16 16 16 15 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM01825.1 - 6e-92 292.2 25.4 1.3e-06 28.0 0.0 19.1 20 0 0 20 20 20 17 Ankyrin repeat Ank_5 PF13857.1 KFM01825.1 - 2.2e-87 285.0 41.7 7.6e-10 38.7 0.2 14.5 5 4 9 15 15 15 14 Ankyrin repeats (many copies) NACHT PF05729.7 KFM01825.1 - 0.0054 16.4 0.2 0.03 13.9 0.1 2.2 1 1 0 1 1 1 1 NACHT domain DUF249 PF03158.8 KFM01825.1 - 0.025 14.1 0.0 13 5.2 0.0 4.0 4 1 0 4 4 4 0 Multigene family 530 protein AAA_17 PF13207.1 KFM01825.1 - 0.1 13.3 0.1 1.9 9.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 KFM01826.1 - 2.6e-84 280.0 0.0 6.7e-43 146.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KFM01826.1 - 2.3e-15 56.3 0.0 2.2e-08 33.4 0.0 3.0 2 2 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KFM01826.1 - 1.3e-11 44.4 0.0 0.00025 20.7 0.0 3.2 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KFM01826.1 - 6.9e-11 42.4 0.0 0.00013 21.9 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 KFM01826.1 - 6e-10 39.3 0.3 0.00066 19.8 0.0 4.5 3 2 0 3 3 2 2 AAA domain TIP49 PF06068.8 KFM01826.1 - 6.3e-10 38.3 0.2 8.6e-05 21.4 0.0 2.5 3 0 0 3 3 2 2 TIP49 C-terminus AAA_2 PF07724.9 KFM01826.1 - 3.2e-09 36.9 0.0 0.00041 20.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 KFM01826.1 - 7.6e-08 33.2 0.0 0.00061 20.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 KFM01826.1 - 1.4e-07 31.1 0.0 0.0057 16.0 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 KFM01826.1 - 2.2e-07 30.8 0.0 0.013 15.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KFM01826.1 - 2.8e-07 29.8 0.0 0.0059 15.7 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin Mg_chelatase PF01078.16 KFM01826.1 - 2.9e-07 29.8 0.7 0.0064 15.6 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 KFM01826.1 - 5.1e-07 29.2 1.8 0.076 12.4 0.0 3.9 2 2 1 4 4 4 2 AAA domain Sigma54_activ_2 PF14532.1 KFM01826.1 - 7.3e-07 29.3 0.0 0.0089 16.0 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain RNA_helicase PF00910.17 KFM01826.1 - 1e-06 28.8 0.0 0.0058 16.7 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_19 PF13245.1 KFM01826.1 - 1.1e-06 28.3 0.5 0.0027 17.4 0.5 3.0 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 KFM01826.1 - 3.7e-06 26.8 0.0 0.0035 17.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.12 KFM01826.1 - 4.7e-06 25.6 0.1 0.0035 16.2 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.1 KFM01826.1 - 5.6e-06 26.4 0.0 0.026 14.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain CDC48_N PF02359.13 KFM01826.1 - 3.2e-05 23.7 0.0 6.6e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_3 PF07726.6 KFM01826.1 - 4e-05 23.2 0.0 0.26 10.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 KFM01826.1 - 0.00012 21.2 0.0 0.077 12.0 0.0 2.5 2 0 0 2 2 2 1 KaiC AAA_18 PF13238.1 KFM01826.1 - 0.00028 21.2 0.0 0.023 15.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 KFM01826.1 - 0.00028 20.4 0.0 0.26 10.7 0.0 3.1 2 1 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.7 KFM01826.1 - 0.00039 20.1 0.6 0.11 12.0 0.0 3.2 4 0 0 4 4 3 1 NACHT domain DUF815 PF05673.8 KFM01826.1 - 0.00041 19.3 0.0 0.19 10.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Rad17 PF03215.10 KFM01826.1 - 0.00051 18.8 0.0 0.073 11.7 0.0 2.4 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_24 PF13479.1 KFM01826.1 - 0.00092 18.8 0.6 0.14 11.7 0.1 2.3 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 KFM01826.1 - 0.0019 18.5 0.0 0.81 9.9 0.0 2.7 2 0 0 2 2 2 1 ABC transporter UPF0079 PF02367.12 KFM01826.1 - 0.002 17.7 0.0 0.26 10.9 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 ATP-synt_ab PF00006.20 KFM01826.1 - 0.0031 17.0 0.0 2 7.8 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain CDC48_2 PF02933.12 KFM01826.1 - 0.0054 16.3 0.0 0.03 13.9 0.0 2.3 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 NB-ARC PF00931.17 KFM01826.1 - 0.0094 14.8 0.1 0.38 9.5 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain SKI PF01202.17 KFM01826.1 - 0.018 14.8 0.0 4.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase AAA_11 PF13086.1 KFM01826.1 - 0.019 14.5 0.1 0.77 9.2 0.0 2.5 3 0 0 3 3 2 0 AAA domain Cytidylate_kin2 PF13189.1 KFM01826.1 - 0.027 14.3 0.0 2.3 8.0 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase-like family IPT PF01745.11 KFM01826.1 - 0.029 13.5 0.1 0.72 8.9 0.1 2.2 2 0 0 2 2 2 0 Isopentenyl transferase PhoH PF02562.11 KFM01826.1 - 0.03 13.5 0.0 0.81 8.8 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein Arch_ATPase PF01637.13 KFM01826.1 - 0.034 13.8 0.0 0.93 9.1 0.0 2.5 2 1 1 3 3 3 0 Archaeal ATPase AAA_23 PF13476.1 KFM01826.1 - 0.062 13.6 0.0 0.63 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.13 KFM01826.1 - 0.13 11.8 0.0 1.3 8.5 0.0 2.4 2 1 0 2 2 2 0 Bacterial dnaA protein DUF2075 PF09848.4 KFM01826.1 - 0.28 10.1 0.0 0.73 8.7 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NUDIX PF00293.23 KFM01827.1 - 4.1e-20 71.7 0.0 5.9e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain FGF PF00167.13 KFM01828.1 - 1.3e-27 96.0 0.0 1.4e-27 95.8 0.0 1.0 1 0 0 1 1 1 1 Fibroblast growth factor IL1 PF00340.14 KFM01828.1 - 0.0006 19.2 0.3 0.0011 18.4 0.2 1.4 1 1 0 1 1 1 1 Interleukin-1 / 18 Cpn60_TCP1 PF00118.19 KFM01829.1 - 1.2e-21 76.8 0.0 1e-09 37.5 0.0 2.6 2 1 0 2 2 2 2 TCP-1/cpn60 chaperonin family EF-hand_1 PF00036.27 KFM01830.1 - 6.3e-35 115.8 17.9 5.3e-09 34.7 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KFM01830.1 - 3.9e-30 103.7 9.8 4.5e-16 58.7 0.4 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KFM01830.1 - 1.9e-27 92.6 11.6 3.2e-09 35.8 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 KFM01830.1 - 1.2e-25 88.8 17.6 1.1e-12 47.3 0.5 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 KFM01830.1 - 7.2e-21 72.5 19.4 2.9e-06 26.3 0.3 4.6 4 1 1 5 5 5 4 EF hand EF-hand_9 PF14658.1 KFM01830.1 - 1.3e-14 53.8 0.1 4.1e-06 26.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KFM01830.1 - 4.5e-06 26.3 8.0 0.21 11.3 0.0 3.3 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand DUF853 PF05872.7 KFM01830.1 - 0.00064 18.1 0.3 0.6 8.3 0.1 2.1 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF853) UPF0154 PF03672.8 KFM01830.1 - 0.0093 15.5 0.2 12 5.5 0.0 3.3 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) TerB PF05099.8 KFM01830.1 - 0.014 15.1 2.6 0.43 10.2 0.1 2.7 1 1 1 3 3 3 0 Tellurite resistance protein TerB SPARC_Ca_bdg PF10591.4 KFM01830.1 - 0.014 15.4 0.6 1.4 9.0 0.2 2.1 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF3349 PF11829.3 KFM01830.1 - 0.021 15.2 0.8 5.9 7.3 0.0 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF3349) DUF4601 PF15373.1 KFM01830.1 - 0.027 13.3 0.2 0.053 12.3 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4601) PB1 PF00564.19 KFM01830.1 - 0.031 13.9 0.6 4.8 6.9 0.1 2.6 2 0 0 2 2 2 0 PB1 domain TBPIP PF07106.8 KFM01830.1 - 0.046 13.2 3.9 2.7 7.5 0.7 2.4 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) PMBR PF09373.5 KFM01830.1 - 0.065 13.2 0.5 58 3.8 0.0 4.2 5 0 0 5 5 5 0 Pseudomurein-binding repeat DUF21 PF01595.15 KFM01830.1 - 0.069 12.4 1.4 0.73 9.0 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF21 SRI PF08236.6 KFM01830.1 - 0.15 12.0 0.1 0.15 12.0 0.1 2.5 3 1 0 3 3 2 0 SRI (Set2 Rpb1 interacting) domain Toprim_2 PF13155.1 KFM01830.1 - 0.18 12.1 1.6 12 6.3 0.0 2.3 1 1 1 2 2 2 0 Toprim-like FlgD PF03963.9 KFM01830.1 - 0.24 11.4 1.4 0.74 9.9 0.2 2.1 2 1 0 2 2 2 0 Flagellar hook capping protein - N-terminal region DUF1542 PF07564.6 KFM01830.1 - 1.7 8.6 5.0 26 4.9 0.0 3.0 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1542) BCNT PF07572.7 KFM01830.1 - 2.3 8.2 5.1 12 5.9 0.1 2.7 3 0 0 3 3 3 0 Bucentaur or craniofacial development IL15 PF02372.10 KFM01831.1 - 2.7e-10 40.1 3.0 3.5e-10 39.7 2.1 1.1 1 0 0 1 1 1 1 Interleukin 15 eRF1_2 PF03464.10 KFM01831.1 - 0.11 12.8 0.1 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 eRF1 domain 2 Uricase PF01014.13 KFM01831.1 - 0.13 12.3 0.2 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 Uricase A_deamin PF02137.13 KFM01832.1 - 3.2e-72 243.7 0.8 6.6e-72 242.7 0.6 1.5 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain dsrm PF00035.20 KFM01832.1 - 2.5e-11 43.9 0.2 2.8e-10 40.6 0.0 2.5 2 0 0 2 2 2 1 Double-stranded RNA binding motif FSA_C PF10479.4 KFM01833.1 - 9.7e-290 962.0 1.3 1.6e-289 961.2 0.9 1.3 1 0 0 1 1 1 1 Fragile site-associated protein C-terminus Ion_trans PF00520.26 KFM01834.1 - 1.6e-36 125.4 15.7 1.6e-36 125.4 10.9 1.6 2 0 0 2 2 2 1 Ion transport protein TRP_2 PF08344.6 KFM01834.1 - 6.7e-31 106.0 2.7 1e-30 105.4 1.0 2.0 2 0 0 2 2 2 1 Transient receptor ion channel II Ank_2 PF12796.2 KFM01834.1 - 1.1e-13 51.2 0.2 9.5e-10 38.6 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) PKD_channel PF08016.7 KFM01834.1 - 8e-13 47.5 16.4 3e-12 45.6 11.4 1.8 1 1 0 1 1 1 1 Polycystin cation channel Ank_4 PF13637.1 KFM01834.1 - 2.4e-11 43.8 0.0 3.7e-07 30.4 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.25 KFM01834.1 - 7.2e-09 35.0 0.8 0.019 14.7 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 KFM01834.1 - 9.3e-09 35.2 0.3 0.097 12.9 0.0 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM01834.1 - 8.2e-08 31.7 1.1 0.83 10.0 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat PBC PF03792.8 KFM01834.1 - 0.041 13.5 0.2 0.29 10.7 0.0 2.0 1 1 1 2 2 2 0 PBC domain DUF3139 PF11337.3 KFM01834.1 - 0.05 13.8 2.4 0.47 10.7 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) BBS2_Mid PF14783.1 KFM01835.1 - 0.0016 18.2 0.0 0.0038 16.9 0.0 1.7 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, middle region GAS PF13851.1 KFM01835.1 - 0.59 9.2 8.7 0.31 10.2 1.0 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF904 PF06005.7 KFM01835.1 - 0.86 9.9 10.2 2.8 8.2 3.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Cyclin_N PF00134.18 KFM01836.1 - 2.2e-50 169.4 0.3 4.8e-50 168.3 0.2 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFM01836.1 - 1.1e-28 99.5 0.3 6.3e-28 97.0 0.1 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain RNase_PH PF01138.16 KFM01837.1 - 3.6e-22 79.0 0.0 7e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KFM01837.1 - 1.8e-10 40.5 0.0 4.8e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Churchill PF06573.6 KFM01838.1 - 3.5e-29 101.0 0.4 3.8e-29 100.9 0.3 1.0 1 0 0 1 1 1 1 Churchill protein zf-CHY PF05495.7 KFM01838.1 - 0.018 15.2 0.7 0.019 15.1 0.5 1.1 1 0 0 1 1 1 0 CHY zinc finger TF_Zn_Ribbon PF08271.7 KFM01838.1 - 0.052 12.8 2.2 0.15 11.3 1.5 1.8 1 1 0 1 1 1 0 TFIIB zinc-binding LIM PF00412.17 KFM01838.1 - 0.073 13.1 1.4 0.085 12.9 1.0 1.1 1 0 0 1 1 1 0 LIM domain Cytochrome_C554 PF13435.1 KFM01838.1 - 0.079 13.0 0.1 0.081 12.9 0.1 1.0 1 0 0 1 1 1 0 Cytochrome c554 and c-prime GSHPx PF00255.14 KFM01839.1 - 1.9e-20 72.2 0.2 2.3e-20 71.9 0.2 1.1 1 0 0 1 1 1 1 Glutathione peroxidase UNC-93 PF05978.11 KFM01840.1 - 5.6e-06 25.9 3.7 5.6e-06 25.9 2.6 2.9 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Aldedh PF00171.17 KFM01841.1 - 6e-85 285.3 0.0 7.5e-85 284.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family 7tm_4 PF13853.1 KFM01842.1 - 8.9e-38 129.3 9.9 8.9e-38 129.3 6.9 2.3 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFM01842.1 - 4e-16 58.9 17.5 6e-16 58.3 12.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 KFM01843.1 - 2e-46 157.3 14.3 2e-46 157.3 9.9 2.3 2 0 0 2 2 2 2 Olfactory receptor 7tm_1 PF00001.16 KFM01843.1 - 5.9e-31 107.5 23.1 7.7e-31 107.1 16.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 KFM01844.1 - 6e-49 165.5 12.8 6e-49 165.5 8.9 2.1 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFM01844.1 - 4.1e-26 91.6 20.4 5e-26 91.3 14.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 KFM01845.1 - 5.1e-49 165.7 15.0 5.1e-49 165.7 10.4 2.2 2 0 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFM01845.1 - 1.8e-31 109.2 22.9 2.2e-31 108.9 15.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 KFM01846.1 - 6.9e-45 152.3 10.5 6.9e-45 152.3 7.3 2.4 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFM01846.1 - 2.8e-29 102.0 20.7 4.2e-29 101.4 14.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 KFM01847.1 - 1.1e-43 148.5 8.9 1.1e-43 148.5 6.2 2.2 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFM01847.1 - 1.5e-30 106.2 18.9 1.9e-30 105.8 13.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM01847.1 - 2.2e-05 23.7 16.8 3.1e-05 23.2 11.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.1 KFM01848.1 - 1.4e-47 161.0 7.0 1.4e-47 161.0 4.9 2.5 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFM01848.1 - 1.3e-29 103.0 17.3 1.8e-29 102.6 12.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM01848.1 - 0.00014 21.0 18.3 0.001 18.2 12.3 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx XPG_N PF00752.12 KFM01849.1 - 8.2e-38 128.7 0.0 2.9e-37 126.9 0.0 1.9 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.13 KFM01849.1 - 2.3e-30 104.4 0.0 5.9e-30 103.1 0.0 1.7 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 KFM01849.1 - 8.6e-08 32.3 0.1 3.6e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Ribosomal_L29e PF01779.12 KFM01849.1 - 0.047 13.5 0.1 0.15 11.9 0.1 1.8 1 0 0 1 1 1 0 Ribosomal L29e protein family UPF0197 PF05251.7 KFM01850.1 - 4.3e-21 74.9 2.4 4.6e-21 74.8 1.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0197) Form_Nir_trans PF01226.12 KFM01850.1 - 0.033 13.0 0.1 0.033 13.0 0.0 1.0 1 0 0 1 1 1 0 Formate/nitrite transporter CcoS PF03597.10 KFM01850.1 - 3.1 7.3 6.0 4.2 6.9 4.2 1.1 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type MRF_C2 PF13888.1 KFM01851.1 - 1.5e-45 154.4 2.2 3e-45 153.4 1.5 1.5 1 0 0 1 1 1 1 Myelin gene regulatory factor C-terminal domain 2 NDT80_PhoG PF05224.7 KFM01851.1 - 3.7e-28 98.7 0.5 3.4e-27 95.6 0.3 2.4 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family MRF_C1 PF13887.1 KFM01851.1 - 1e-23 81.9 1.7 1.8e-23 81.2 1.2 1.4 1 0 0 1 1 1 1 Myelin gene regulatory factor -C-terminal domain 1 Peptidase_S74 PF13884.1 KFM01851.1 - 7.9e-15 54.7 0.1 1.5e-14 53.8 0.1 1.5 1 0 0 1 1 1 1 Chaperone of endosialidase Lipase_3 PF01764.20 KFM01852.1 - 1.1e-10 41.3 0.0 2.8e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) LRR_4 PF12799.2 KFM01853.1 - 1.4e-10 40.4 0.0 4.5e-06 26.1 0.0 2.7 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM01853.1 - 2e-07 30.0 0.1 0.52 10.5 0.1 3.6 3 0 0 3 3 3 3 Leucine Rich Repeat LRR_8 PF13855.1 KFM01853.1 - 2.7e-07 30.2 0.0 0.00034 20.3 0.0 2.3 2 0 0 2 2 2 2 Leucine rich repeat LRR_7 PF13504.1 KFM01853.1 - 5.6e-06 25.6 0.9 2.1 8.9 0.0 3.9 3 1 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.1 KFM01853.1 - 0.14 12.3 0.4 44 4.5 0.2 3.1 2 1 0 2 2 2 0 Leucine Rich repeat Sdh5 PF03937.11 KFM01854.1 - 7.6e-15 54.3 0.6 1.1e-14 53.8 0.4 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase R-HINP1I PF11463.3 KFM01854.1 - 0.11 11.8 0.3 0.13 11.6 0.2 1.0 1 0 0 1 1 1 0 R.HinP1I restriction endonuclease Lectin_leg-like PF03388.8 KFM01855.1 - 3.4e-78 261.9 0.1 4.7e-78 261.4 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family DUF4407 PF14362.1 KFM01855.1 - 0.048 12.6 3.5 0.072 12.0 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3086 PF11285.3 KFM01855.1 - 0.058 12.1 4.1 0.043 12.6 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3086) OmpH PF03938.9 KFM01855.1 - 0.46 10.4 11.4 3.7 7.4 7.9 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) ApoLp-III PF07464.6 KFM01855.1 - 1.2 9.1 6.2 1.1 9.2 0.4 2.7 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) V-SNARE PF05008.10 KFM01855.1 - 1.4 9.1 8.0 0.21 11.7 1.2 2.7 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Rootletin PF15035.1 KFM01855.1 - 1.6 8.6 9.0 7 6.5 0.7 2.4 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Synaphin PF05835.7 KFM01857.1 - 1.2e-24 87.1 11.0 1.6e-24 86.6 7.6 1.2 1 0 0 1 1 1 1 Synaphin protein DUF1476 PF07345.6 KFM01857.1 - 0.83 9.9 7.7 1.7 8.9 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1476) AHSP PF09236.5 KFM01857.1 - 1.2 9.4 4.3 0.39 10.9 0.6 1.9 2 0 0 2 2 2 0 Alpha-haemoglobin stabilising protein DUF4449 PF14613.1 KFM01857.1 - 9.5 6.1 9.3 1.3 8.9 1.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4449) Peptidase_S24 PF00717.18 KFM01858.1 - 1.9e-11 43.4 0.1 2.8e-11 42.8 0.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like DUF504 PF04457.7 KFM01858.1 - 0.034 14.2 1.0 0.069 13.3 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF504) Laminin_G_1 PF00054.18 KFM01859.1 - 5.1e-16 58.8 0.0 6e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 Laminin G domain Laminin_G_2 PF02210.19 KFM01859.1 - 1.1e-14 54.5 0.0 1.3e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Laminin G domain UCH PF00443.24 KFM01860.1 - 8.3e-47 159.5 3.8 8.3e-47 159.5 2.7 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFM01860.1 - 4e-27 95.4 1.2 4e-27 95.4 0.8 2.6 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 KFM01860.1 - 6.2e-09 36.1 3.3 0.0019 18.5 0.0 4.3 4 0 0 4 4 4 2 DUSP domain ubiquitin PF00240.18 KFM01860.1 - 1.6e-05 24.1 0.0 3.9e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Peptidase_M13_N PF05649.8 KFM01861.1 - 2.7e-128 428.3 1.2 3.3e-128 428.0 0.8 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 KFM01861.1 - 2.8e-31 108.2 0.4 9.2e-31 106.6 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M13 Tim17 PF02466.14 KFM01861.1 - 0.093 12.7 0.2 0.25 11.3 0.1 1.7 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family MIF4G PF02854.14 KFM01862.1 - 9.9e-68 227.6 7.9 2.1e-67 226.5 5.5 1.6 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 KFM01862.1 - 1.1e-30 105.6 0.4 4.4e-30 103.7 0.1 2.3 2 0 0 2 2 2 1 MA3 domain W2 PF02020.13 KFM01862.1 - 4.1e-17 61.8 5.1 5.8e-17 61.4 0.8 2.8 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Linker_histone PF00538.14 KFM01863.1 - 5e-43 145.0 0.6 2e-15 56.6 0.0 3.4 3 0 0 3 3 3 3 linker histone H1 and H5 family SDA1 PF05285.7 KFM01863.1 - 0.00038 19.8 26.1 0.0061 15.8 3.1 2.4 2 0 0 2 2 2 2 SDA1 Transglycosylas PF06737.9 KFM01863.1 - 0.015 15.5 2.0 5.5 7.3 0.0 3.7 4 0 0 4 4 4 0 Transglycosylase-like domain Daxx PF03344.10 KFM01863.1 - 0.15 10.5 32.9 0.11 10.9 7.5 2.3 2 0 0 2 2 2 0 Daxx Family DUF1510 PF07423.6 KFM01863.1 - 0.22 10.8 37.1 0.18 11.1 11.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Nop14 PF04147.7 KFM01863.1 - 0.35 8.7 38.9 0.19 9.6 10.8 2.2 2 0 0 2 2 2 0 Nop14-like family DUF2890 PF11081.3 KFM01863.1 - 5.4 7.0 41.0 0.36 10.8 13.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Kinesin PF00225.18 KFM01864.1 - 3.3e-34 118.1 0.1 3.4e-34 118.0 0.1 1.0 1 0 0 1 1 1 1 Kinesin motor domain AAA_10 PF12846.2 KFM01864.1 - 0.0012 18.3 0.0 0.0012 18.3 0.0 1.1 1 0 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 KFM01864.1 - 0.014 15.4 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.9 KFM01864.1 - 0.036 13.0 0.3 0.054 12.4 0.2 1.3 1 1 0 1 1 1 0 PIF1-like helicase AAA_16 PF13191.1 KFM01864.1 - 0.04 13.9 0.0 0.042 13.8 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.12 KFM01864.1 - 0.06 13.1 0.1 0.094 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF87 NACHT PF05729.7 KFM01864.1 - 0.073 12.7 0.0 0.075 12.6 0.0 1.1 1 0 0 1 1 1 0 NACHT domain DUF2791 PF10923.3 KFM01864.1 - 0.11 11.0 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) CDT1 PF08839.6 KFM01865.1 - 0.051 13.5 1.1 0.67 9.8 0.1 2.3 1 1 1 2 2 2 0 DNA replication factor CDT1 like DIT1_PvcA PF05141.7 KFM01865.1 - 0.36 10.1 2.9 0.71 9.1 2.0 1.6 1 1 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein CorA PF01544.13 KFM01865.1 - 0.5 9.3 3.7 0.65 8.9 2.6 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DivIC PF04977.10 KFM01865.1 - 0.59 9.6 11.8 0.16 11.4 2.7 2.5 2 0 0 2 2 2 0 Septum formation initiator BBP1_C PF15272.1 KFM01865.1 - 0.72 9.3 15.4 0.032 13.7 4.5 2.0 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal APG6 PF04111.7 KFM01865.1 - 4.5 6.2 12.9 5.9 5.8 9.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_23 PF13476.1 KFM01865.1 - 7.4 6.8 9.1 11 6.3 6.3 1.3 1 0 0 1 1 1 0 AAA domain DDOST_48kD PF03345.9 KFM01866.1 - 8.8e-150 498.9 0.0 9.8e-150 498.7 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Asp_protease PF09668.5 KFM01867.1 - 1.4e-39 134.4 1.0 1.7e-39 134.1 0.7 1.1 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 KFM01867.1 - 7.6e-05 22.6 0.1 8.2e-05 22.5 0.1 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KFM01867.1 - 0.00031 21.1 0.0 0.00081 19.8 0.0 1.6 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 KFM01867.1 - 0.012 15.4 0.1 0.028 14.3 0.0 1.7 2 0 0 2 2 2 0 Retroviral aspartyl protease UBA PF00627.26 KFM01868.1 - 0.00067 19.4 0.1 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain RUN PF02759.14 KFM01869.1 - 8.3e-17 61.1 3.5 2.2e-16 59.8 2.4 1.8 1 0 0 1 1 1 1 RUN domain PH PF00169.24 KFM01869.1 - 1.6e-12 47.4 0.0 1.2e-11 44.7 0.0 2.5 3 0 0 3 3 3 1 PH domain PH_9 PF15410.1 KFM01869.1 - 0.00073 19.6 0.0 0.062 13.4 0.0 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain Mito_carr PF00153.22 KFM01870.1 - 1.1e-27 95.6 0.1 6.4e-17 61.0 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein LIM PF00412.17 KFM01872.1 - 7.4e-37 125.2 32.4 1.4e-13 50.6 5.1 3.2 3 0 0 3 3 3 3 LIM domain DUF678 PF05077.7 KFM01872.1 - 6.1 6.8 21.4 0.26 11.3 0.4 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF678) RRM_1 PF00076.17 KFM01873.1 - 4.2e-28 96.7 1.2 2.2e-14 52.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM01873.1 - 1.9e-21 75.7 0.2 1e-08 35.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM01873.1 - 5.4e-15 54.9 3.2 4.5e-06 26.4 0.1 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFM01873.1 - 0.0052 16.6 0.1 2 8.2 0.0 2.5 3 0 0 3 3 3 2 RNA binding motif SPOC PF07744.8 KFM01875.1 - 1.8e-15 57.4 0.0 2.3e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 SPOC domain HSP20 PF00011.16 KFM01876.1 - 1.2e-14 54.0 0.0 1.4e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Kelch_3 PF13415.1 KFM01877.1 - 1.6e-29 101.3 10.2 3.1e-09 36.7 0.0 6.8 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.1 KFM01877.1 - 2.4e-28 97.6 4.8 3.9e-09 36.1 0.1 5.6 3 1 2 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.1 KFM01877.1 - 6.3e-22 77.0 0.8 1.5e-07 31.1 0.0 5.7 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 KFM01877.1 - 3.6e-19 67.7 9.8 1.9e-08 33.7 0.2 6.5 7 0 0 7 7 7 3 Kelch motif Kelch_6 PF13964.1 KFM01877.1 - 5.5e-18 64.3 5.8 3.2e-05 23.9 0.0 5.5 4 1 1 5 5 5 3 Kelch motif Kelch_1 PF01344.20 KFM01877.1 - 8e-18 63.7 0.3 2.5e-06 26.8 0.0 5.7 5 0 0 5 5 5 3 Kelch motif F-box-like PF12937.2 KFM01877.1 - 3.6e-09 36.1 1.1 4.9e-09 35.7 0.0 1.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KFM01877.1 - 2.8e-07 30.0 0.0 5.6e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 F-box domain SUZ PF12752.2 KFM01878.1 - 1e-13 51.5 0.1 1e-13 51.5 0.1 2.0 3 0 0 3 3 3 1 SUZ domain SUZ-C PF12901.2 KFM01878.1 - 4.5e-11 42.1 5.7 4.5e-11 42.1 3.9 1.9 2 0 0 2 2 2 1 SUZ-C motif DUF1681 PF07933.9 KFM01879.1 - 4.4e-45 153.1 0.0 5.2e-45 152.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) E1-E2_ATPase PF00122.15 KFM01880.1 - 3.2e-36 124.5 0.1 4.3e-36 124.0 0.1 1.1 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.21 KFM01880.1 - 0.00015 21.1 0.1 0.00035 19.9 0.1 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KFM01880.1 - 0.0012 19.0 0.0 0.002 18.3 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFM01880.1 - 0.015 15.7 0.0 0.024 15.0 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase MARVEL PF01284.18 KFM01880.1 - 0.024 14.4 4.3 0.056 13.2 0.4 2.3 2 0 0 2 2 2 0 Membrane-associating domain Fer2_3 PF13085.1 KFM01881.1 - 1.4e-31 108.5 0.0 2.6e-31 107.7 0.0 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 KFM01881.1 - 3.4e-10 40.1 5.6 3.4e-10 40.1 3.9 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 KFM01881.1 - 3.1e-09 36.7 4.2 3.1e-09 36.7 2.9 2.1 2 1 1 3 3 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 KFM01881.1 - 3.9e-08 33.6 6.3 9.5e-07 29.1 0.8 2.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 KFM01881.1 - 0.00036 20.7 10.1 0.026 14.7 0.6 3.4 3 1 0 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 KFM01881.1 - 0.0012 18.6 6.0 0.0012 18.6 4.2 2.7 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 KFM01881.1 - 0.0087 15.7 2.9 0.014 15.1 0.1 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.2 KFM01881.1 - 0.015 15.6 7.2 0.015 15.6 5.0 3.1 2 2 1 3 3 3 0 4Fe-4S dicluster domain Fer4_15 PF13459.1 KFM01881.1 - 4.3 7.9 8.6 1.9 9.1 0.1 3.1 4 0 0 4 4 4 0 4Fe-4S single cluster domain Fer4_16 PF13484.1 KFM01881.1 - 7.4 7.4 14.8 8.6 7.1 1.2 3.6 3 1 0 3 3 3 0 4Fe-4S double cluster binding domain PAD PF03068.10 KFM01882.1 - 4.9e-204 677.0 0.0 6e-204 676.7 0.0 1.1 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) PAD_M PF08527.5 KFM01882.1 - 8.5e-63 210.5 0.0 1.5e-62 209.7 0.0 1.4 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) middle domain PAD_N PF08526.5 KFM01882.1 - 3e-28 98.1 0.0 5.5e-28 97.2 0.0 1.5 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) N-terminal domain RhoGEF PF00621.15 KFM01883.1 - 9.2e-35 120.1 0.8 2.2e-34 118.9 0.4 1.7 2 0 0 2 2 2 1 RhoGEF domain DUF1690 PF07956.6 KFM01883.1 - 0.013 15.5 1.2 0.029 14.3 0.8 1.5 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) Cytochrom_D1 PF02239.11 KFM01883.1 - 0.14 10.4 0.0 0.24 9.6 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain GATase_4 PF13230.1 KFM01883.1 - 0.2 10.3 0.1 0.37 9.4 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferases class-II PAX PF00292.13 KFM01884.1 - 4.6e-75 249.3 0.8 7.1e-75 248.7 0.6 1.3 1 0 0 1 1 1 1 'Paired box' domain Homeobox PF00046.24 KFM01884.1 - 1.9e-23 81.7 6.9 1.9e-23 81.7 4.8 1.7 2 0 0 2 2 2 1 Homeobox domain Pax7 PF12360.3 KFM01884.1 - 3.6e-21 75.1 8.5 9.7e-21 73.7 5.9 1.8 1 0 0 1 1 1 1 Paired box protein 7 HTH_23 PF13384.1 KFM01884.1 - 3.5e-06 26.4 1.0 0.00054 19.5 0.0 2.6 2 0 0 2 2 2 2 Homeodomain-like domain HTH_32 PF13565.1 KFM01884.1 - 1.6e-05 25.5 4.9 0.0078 16.9 0.1 2.9 2 1 0 2 2 2 2 Homeodomain-like domain Homeobox_KN PF05920.6 KFM01884.1 - 4.2e-05 23.1 0.4 0.00013 21.5 0.3 1.9 1 0 0 1 1 1 1 Homeobox KN domain Aldedh PF00171.17 KFM01885.1 - 1.2e-99 333.7 0.0 1.5e-99 333.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Filament PF00038.16 KFM01886.1 - 1.9e-20 73.5 16.6 1.2e-11 44.6 0.3 2.1 2 0 0 2 2 2 2 Intermediate filament protein Snapin_Pallidin PF14712.1 KFM01886.1 - 0.00019 21.6 0.8 0.00063 20.0 0.5 1.9 1 0 0 1 1 1 1 Snapin/Pallidin TMF_DNA_bd PF12329.3 KFM01886.1 - 0.018 14.8 1.9 0.018 14.8 1.3 2.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Prefoldin PF02996.12 KFM01886.1 - 0.066 12.8 5.2 1.8 8.2 0.2 2.7 2 0 0 2 2 2 0 Prefoldin subunit TLE_N PF03920.10 KFM01886.1 - 2.5 7.9 6.6 0.73 9.6 0.3 2.8 3 1 0 3 3 3 0 Groucho/TLE N-terminal Q-rich domain CENP-Q PF13094.1 KFM01886.1 - 3.1 7.7 13.6 3.6 7.6 1.8 3.1 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1620 PF07774.8 KFM01887.1 - 3.8e-64 215.9 0.0 8e-64 214.8 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 KFM01887.1 - 7.9e-13 48.4 0.8 6e-08 32.4 0.2 3.5 2 1 1 3 3 3 2 PQQ-like domain PQQ PF01011.16 KFM01887.1 - 3.1e-05 23.2 0.1 0.13 11.8 0.0 3.6 4 0 0 4 4 4 2 PQQ enzyme repeat Aldo_ket_red PF00248.16 KFM01888.1 - 7.7e-41 139.7 0.0 8.7e-41 139.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PQ-loop PF04193.9 KFM01889.1 - 2.2e-17 62.3 7.7 3.2e-12 45.7 1.3 2.7 2 0 0 2 2 2 2 PQ loop repeat F_actin_cap_B PF01115.12 KFM01890.1 - 1.3e-111 371.5 0.0 1.6e-111 371.3 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit CENP-C_mid PF15620.1 KFM01890.1 - 0.035 13.8 0.7 0.046 13.4 0.5 1.2 1 0 0 1 1 1 0 Centromere assembly component CENP-C middle DNMT3B-binding region DUF543 PF04418.7 KFM01891.1 - 3e-27 94.3 0.8 3.2e-27 94.2 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) DAN PF03045.10 KFM01892.1 - 1.1e-33 115.2 4.5 1.4e-33 114.8 3.2 1.1 1 0 0 1 1 1 1 DAN domain Cys_knot PF00007.17 KFM01892.1 - 8.1e-07 29.0 6.5 1.1e-06 28.6 4.5 1.1 1 0 0 1 1 1 1 Cystine-knot domain 7tm_1 PF00001.16 KFM01893.1 - 1.3e-68 230.9 12.1 1.6e-68 230.6 8.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM01893.1 - 1.2e-05 24.5 5.3 1.2e-05 24.5 3.7 2.4 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM01893.1 - 0.001 18.2 9.8 0.0019 17.3 6.8 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF726 PF05277.7 KFM01894.1 - 1.9e-122 408.5 2.9 2.3e-122 408.1 2.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF900 PF05990.7 KFM01894.1 - 0.00021 20.6 0.0 0.00035 19.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.10 KFM01894.1 - 0.0015 17.5 0.0 0.0024 16.9 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase VirJ PF06057.6 KFM01894.1 - 0.0076 16.0 0.0 0.048 13.4 0.0 2.1 2 0 0 2 2 2 1 Bacterial virulence protein (VirJ) Lipase_3 PF01764.20 KFM01894.1 - 0.024 14.2 0.2 0.061 12.9 0.0 1.8 2 0 0 2 2 2 0 Lipase (class 3) DUF2566 PF10753.4 KFM01894.1 - 0.049 13.5 1.4 0.11 12.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2566) Cutinase PF01083.17 KFM01894.1 - 0.056 13.1 0.0 0.095 12.4 0.0 1.3 1 0 0 1 1 1 0 Cutinase Pro-NT_NN PF07421.6 KFM01894.1 - 0.081 12.4 0.2 0.2 11.1 0.0 1.6 2 0 0 2 2 2 0 Neurotensin/neuromedin N precursor Abhydrolase_6 PF12697.2 KFM01894.1 - 0.088 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family UPF0565 PF10561.4 KFM01894.1 - 0.096 11.5 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Thioesterase PF00975.15 KFM01894.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain 5TM-5TMR_LYT PF07694.7 KFM01894.1 - 4.3 6.6 11.3 11 5.2 7.7 1.8 1 1 0 1 1 1 0 5TMR of 5TMR-LYT OTU PF02338.14 KFM01895.1 - 3.8e-14 53.2 2.2 4e-14 53.2 0.0 2.1 3 0 0 3 3 3 1 OTU-like cysteine protease UBA_4 PF14555.1 KFM01895.1 - 0.0013 18.2 0.1 0.0024 17.3 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain Peptidase_C65 PF10275.4 KFM01895.1 - 0.074 12.3 0.0 0.074 12.3 0.0 3.0 2 1 1 3 3 3 0 Peptidase C65 Otubain Coatamer_beta_C PF07718.7 KFM01895.1 - 0.14 11.7 0.1 0.14 11.7 0.1 2.1 2 0 0 2 2 2 0 Coatomer beta C-terminal region Phospholip_A2_1 PF00068.14 KFM01896.1 - 1e-35 122.4 17.4 1.2e-35 122.2 12.1 1.0 1 0 0 1 1 1 1 Phospholipase A2 Phospholip_A2_2 PF05826.7 KFM01896.1 - 0.0014 18.5 14.1 0.053 13.4 9.8 2.2 1 1 0 1 1 1 1 Phospholipase A2 Phospholip_A2_1 PF00068.14 KFM01897.1 - 6.7e-23 81.1 1.9 7e-23 81.0 1.3 1.0 1 0 0 1 1 1 1 Phospholipase A2 Parvo_coat_N PF08398.5 KFM01897.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.5 1 1 1 2 2 2 0 Parvovirus coat protein VP1 PsbJ PF01788.12 KFM01897.1 - 0.071 12.6 0.1 0.093 12.2 0.1 1.2 1 0 0 1 1 1 0 PsbJ Phospholip_A2_2 PF05826.7 KFM01897.1 - 0.62 10.0 5.4 0.79 9.7 3.6 1.4 1 1 0 1 1 1 0 Phospholipase A2 Phospholip_A2_1 PF00068.14 KFM01898.1 - 2.2e-23 82.6 2.8 2.4e-23 82.5 1.9 1.0 1 0 0 1 1 1 1 Phospholipase A2 Parvo_coat_N PF08398.5 KFM01898.1 - 0.053 13.3 0.0 0.065 13.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus coat protein VP1 Phospholip_A2_2 PF05826.7 KFM01898.1 - 1.3 9.0 6.5 1.9 8.4 4.5 1.5 1 1 0 1 1 1 0 Phospholipase A2 Adeno_E3_CR2 PF02439.10 KFM01898.1 - 4.8 6.8 6.0 8.8 5.9 4.1 1.5 1 1 0 1 1 1 0 Adenovirus E3 region protein CR2 UBX PF00789.15 KFM01899.1 - 5.1e-09 36.0 0.0 1e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 UBX domain DEAD PF00270.24 KFM01900.1 - 4e-31 107.7 0.0 2.4e-30 105.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFM01900.1 - 8.3e-26 89.6 2.1 2.6e-25 88.0 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF1811 PF08838.5 KFM01900.1 - 0.043 13.7 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1811) GIDE PF12483.3 KFM01901.1 - 1.4e-25 89.4 0.0 2.6e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 E3 Ubiquitin ligase zf-C3HC4_3 PF13920.1 KFM01901.1 - 5.7e-13 48.3 15.1 9.2e-13 47.6 10.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM01901.1 - 3.9e-05 23.5 17.9 6.8e-05 22.8 12.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM01901.1 - 0.00018 21.1 15.7 0.00031 20.4 10.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KFM01901.1 - 0.019 14.8 15.6 0.035 13.9 10.8 1.5 1 0 0 1 1 1 0 Ring finger domain COX6A PF02046.10 KFM01901.1 - 0.061 13.2 0.1 0.13 12.1 0.0 1.5 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIa DUF327 PF03885.8 KFM01901.1 - 0.071 12.9 0.4 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF327) UPF0104 PF03706.8 KFM01901.1 - 0.13 11.5 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) Prok-RING_4 PF14447.1 KFM01901.1 - 2.2 7.9 10.5 5.7 6.5 7.3 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Pkinase PF00069.20 KFM01903.1 - 9.5e-28 97.0 0.0 2.2e-27 95.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM01903.1 - 5.4e-15 55.1 0.0 1.3e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM01903.1 - 0.0044 16.0 0.0 0.0085 15.0 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KFM01903.1 - 0.011 15.4 0.3 0.029 14.1 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KFM01903.1 - 0.04 13.2 0.0 0.097 11.9 0.0 1.5 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Arginase PF00491.16 KFM01904.1 - 4.8e-91 304.9 0.0 5.6e-91 304.6 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 KFM01904.1 - 0.028 14.6 0.0 0.04 14.1 0.0 1.2 1 0 0 1 1 1 0 UPF0489 domain Thioredoxin PF00085.15 KFM01905.1 - 1.3e-09 37.6 0.0 2.9e-07 30.1 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_3 PF13192.1 KFM01905.1 - 0.0033 17.1 0.0 0.0071 16.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_8 PF13905.1 KFM01905.1 - 0.028 14.5 0.4 16 5.6 0.0 4.0 4 0 0 4 4 4 0 Thioredoxin-like Peptidase_C14 PF00656.17 KFM01906.1 - 1.1e-43 149.7 0.0 1.4e-43 149.4 0.0 1.1 1 0 0 1 1 1 1 Caspase domain CARD PF00619.16 KFM01906.1 - 1.3e-05 24.9 0.0 2.8e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Caspase recruitment domain Trypsin PF00089.21 KFM01907.1 - 2e-17 63.5 0.1 2.1e-17 63.4 0.1 1.0 1 0 0 1 1 1 1 Trypsin EF-hand_7 PF13499.1 KFM01908.1 - 4.2e-08 33.1 0.4 9.6e-08 32.0 0.3 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KFM01908.1 - 1.1e-07 30.6 6.5 0.001 18.2 0.3 2.7 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 KFM01908.1 - 0.00024 20.7 1.8 0.041 13.7 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 KFM01908.1 - 0.00054 19.5 0.9 0.0011 18.5 0.7 1.5 1 0 0 1 1 1 1 EF-hand domain pair Decorin_bind PF02352.10 KFM01908.1 - 0.012 15.6 4.7 0.16 11.9 1.0 2.1 2 0 0 2 2 2 0 Decorin binding protein PcfJ PF14284.1 KFM01908.1 - 0.049 13.1 2.2 0.069 12.6 1.5 1.2 1 0 0 1 1 1 0 PcfJ-like protein EF-hand_5 PF13202.1 KFM01908.1 - 0.59 9.5 0.1 0.59 9.5 0.0 2.9 4 0 0 4 4 4 0 EF hand FAM165 PF14981.1 KFM01908.1 - 0.83 9.2 4.4 1.6 8.3 3.0 1.5 1 0 0 1 1 1 0 FAM165 family YqgF PF14639.1 KFM01909.1 - 0.0041 16.7 0.7 0.007 15.9 0.3 1.4 1 1 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 TAF PF02969.12 KFM01909.1 - 0.09 12.7 1.3 0.28 11.1 0.0 2.3 2 1 1 3 3 3 0 TATA box binding protein associated factor (TAF) DUF342 PF03961.8 KFM01909.1 - 0.23 9.8 5.0 0.25 9.7 3.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) VPS11_C PF12451.3 KFM01909.1 - 1.7 8.5 5.4 23 4.9 0.0 2.7 2 1 1 3 3 3 0 Vacuolar protein sorting protein 11 C terminal DivIVA PF05103.8 KFM01909.1 - 2.6 8.1 11.9 3.1 7.8 3.6 2.1 1 1 1 2 2 2 0 DivIVA protein FHA PF00498.21 KFM01910.1 - 4.1e-15 55.6 0.0 1e-14 54.3 0.0 1.7 1 0 0 1 1 1 1 FHA domain DUF3584 PF12128.3 KFM01910.1 - 3.9e-06 24.5 17.9 4.7e-06 24.2 12.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) ATG16 PF08614.6 KFM01910.1 - 0.0016 18.3 24.8 0.074 12.8 6.5 2.6 1 1 2 3 3 3 3 Autophagy protein 16 (ATG16) ADIP PF11559.3 KFM01910.1 - 0.014 15.3 25.5 0.024 14.5 4.1 3.1 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Phage_portal_2 PF05136.8 KFM01910.1 - 0.014 13.9 0.0 0.026 13.0 0.0 1.3 1 0 0 1 1 1 0 Phage portal protein, lambda family Phage_Mu_Gam PF07352.7 KFM01910.1 - 0.014 14.8 6.4 0.014 14.8 4.4 2.5 2 1 0 2 2 2 0 Bacteriophage Mu Gam like protein APG6 PF04111.7 KFM01910.1 - 0.056 12.4 24.1 0.31 10.0 2.7 2.2 1 1 0 2 2 2 0 Autophagy protein Apg6 CENP-Q PF13094.1 KFM01910.1 - 0.092 12.7 22.7 0.31 11.0 2.5 2.5 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Mu-like_Pro PF10123.4 KFM01910.1 - 0.11 11.9 7.2 0.17 11.3 5.0 1.3 1 0 0 1 1 1 0 Mu-like prophage I protein Spc7 PF08317.6 KFM01910.1 - 0.11 11.1 24.3 0.028 13.0 4.0 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Pox_A_type_inc PF04508.7 KFM01910.1 - 0.15 11.9 7.9 2.8 7.9 0.1 3.9 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Fib_alpha PF08702.5 KFM01910.1 - 0.15 12.1 13.8 1.1 9.4 3.1 2.8 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.6 KFM01910.1 - 0.27 11.1 10.4 0.56 10.1 0.9 3.9 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) IncA PF04156.9 KFM01910.1 - 0.55 9.8 28.1 1.5e+04 -5.5 19.6 2.9 1 1 0 1 1 0 0 IncA protein AAA_13 PF13166.1 KFM01910.1 - 0.74 8.2 19.5 1.2 7.4 12.2 2.1 1 1 0 1 1 1 0 AAA domain DUF1664 PF07889.7 KFM01910.1 - 0.97 9.2 12.4 2.3 8.0 1.0 3.2 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) CCDC-167 PF15188.1 KFM01910.1 - 0.99 9.3 15.5 0.18 11.7 4.6 3.4 2 2 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF948 PF06103.6 KFM01910.1 - 2.5 7.9 8.2 12 5.8 0.0 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) TMF_DNA_bd PF12329.3 KFM01910.1 - 3.2 7.6 34.4 4.5 7.1 8.5 4.4 2 2 1 3 3 3 0 TATA element modulatory factor 1 DNA binding TSC22 PF01166.13 KFM01910.1 - 3.2 7.7 0.0 3.2 7.7 0.0 3.8 4 0 0 4 4 4 0 TSC-22/dip/bun family Nsp1_C PF05064.8 KFM01910.1 - 3.3 7.3 10.8 2 8.0 1.7 3.2 1 1 1 3 3 3 0 Nsp1-like C-terminal region CENP-F_leu_zip PF10473.4 KFM01910.1 - 4.2 7.2 29.7 0.94 9.3 11.0 2.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Bap31 PF05529.7 KFM01910.1 - 5.3 6.4 19.3 0.73 9.2 1.8 2.7 2 1 1 3 3 3 0 B-cell receptor-associated protein 31-like UPF0231 PF06062.6 KFM01910.1 - 5.9 6.7 7.3 26 4.7 1.5 2.9 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0231) Prefoldin PF02996.12 KFM01910.1 - 6.5 6.4 17.6 10 5.7 1.3 4.2 4 0 0 4 4 4 0 Prefoldin subunit DUF641 PF04859.7 KFM01910.1 - 7.4 6.3 21.6 23 4.7 0.3 4.5 1 1 3 5 5 5 0 Plant protein of unknown function (DUF641) SlyX PF04102.7 KFM01910.1 - 8.8 6.7 20.1 4.6 7.6 1.4 4.5 3 1 2 5 5 5 0 SlyX TMEM51 PF15345.1 KFM01911.1 - 3.3e-94 314.9 0.1 3.8e-94 314.7 0.1 1.0 1 0 0 1 1 1 1 Transmembrane protein 51 TMEM61 PF15105.1 KFM01911.1 - 9.9e-05 21.9 1.4 0.0024 17.4 0.0 2.7 1 1 1 3 3 3 1 TMEM61 protein family RCR PF12273.3 KFM01911.1 - 0.019 15.5 0.0 0.035 14.6 0.0 1.7 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red FAM176 PF14851.1 KFM01911.1 - 0.041 13.5 0.1 0.061 13.0 0.1 1.3 1 0 0 1 1 1 0 FAM176 family WBP-1 PF11669.3 KFM01911.1 - 0.079 13.0 0.1 0.77 9.8 0.0 2.4 3 0 0 3 3 3 0 WW domain-binding protein 1 DUF148 PF02520.12 KFM01912.1 - 0.0059 16.3 7.3 0.02 14.6 5.1 1.9 1 0 0 1 1 1 1 Domain of unknown function DUF148 DUF4200 PF13863.1 KFM01912.1 - 0.016 15.1 22.7 0.016 15.1 15.8 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4200) AAA_13 PF13166.1 KFM01912.1 - 0.033 12.6 18.6 0.046 12.1 12.9 1.1 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.1 KFM01912.1 - 0.077 10.6 27.2 0.12 10.0 18.9 1.3 1 0 0 1 1 1 0 AAA domain DivIC PF04977.10 KFM01912.1 - 1.2 8.6 34.5 0.64 9.5 0.1 4.6 3 1 1 5 5 5 0 Septum formation initiator DUF4279 PF14106.1 KFM01912.1 - 1.5 8.6 8.5 4.2 7.2 0.1 2.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4279) CENP-F_leu_zip PF10473.4 KFM01912.1 - 4 7.2 42.0 2.4 7.9 9.3 3.5 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CALCOCO1 PF07888.6 KFM01912.1 - 5.3 5.2 22.2 12 4.0 15.4 1.6 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like PA26 PF04636.8 KFM01912.1 - 5.9 5.4 10.3 3.7 6.1 5.9 1.5 1 1 1 2 2 2 0 PA26 p53-induced protein (sestrin) Baculo_PEP_C PF04513.7 KFM01912.1 - 9.6 6.0 6.6 10 5.9 1.5 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMF_TATA_bd PF12325.3 KFM01912.1 - 9.7 5.9 35.0 0.79 9.4 6.3 4.0 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding HALZ PF02183.13 KFM01912.1 - 9.9 5.9 20.4 3.6 7.3 1.0 4.0 3 1 0 3 3 3 0 Homeobox associated leucine zipper Cas6 PF09559.5 KFM01913.1 - 0.0091 15.7 0.1 0.011 15.4 0.1 1.0 1 0 0 1 1 1 1 Cas6 Crispr zf-C2H2_4 PF13894.1 KFM01914.1 - 2.1e-18 65.2 56.3 0.003 17.7 3.5 8.9 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2 PF00096.21 KFM01914.1 - 3.1e-17 61.7 66.4 0.0067 16.7 1.3 8.8 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KFM01914.1 - 3.2e-06 27.1 27.1 0.012 15.7 0.5 6.8 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 KFM01914.1 - 0.03 14.6 63.6 0.041 14.1 0.4 10.4 11 0 0 11 11 11 0 Zinc-finger double domain PyrI_C PF02748.10 KFM01914.1 - 0.36 10.3 19.9 0.86 9.0 0.3 6.0 6 1 1 7 7 7 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-CHCC PF10276.4 KFM01914.1 - 4.9 7.0 12.3 8.1 6.3 0.0 4.1 5 0 0 5 5 5 0 Zinc-finger domain zf-RING_3 PF14369.1 KFM01914.1 - 5.3 7.1 9.9 2.1 8.4 0.1 4.3 4 0 0 4 4 4 0 zinc-finger zf-C2H2_2 PF12756.2 KFM01914.1 - 8.1 6.6 36.4 9.9 6.3 0.0 7.8 5 2 2 7 7 7 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 KFM01914.1 - 8.4 6.4 51.0 0.031 14.1 1.5 7.6 8 0 0 8 8 8 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KFM01914.1 - 9.8 5.9 30.0 1.4 8.6 0.3 6.3 6 0 0 6 6 6 0 zinc-finger of a C2HC-type Podoplanin PF05808.6 KFM01915.1 - 6.2e-18 64.8 0.6 6.8e-18 64.7 0.4 1.1 1 0 0 1 1 1 1 Podoplanin Herpes_gE PF02480.11 KFM01915.1 - 0.12 10.6 0.0 0.13 10.4 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E VSP PF03302.8 KFM01915.1 - 0.21 10.2 0.6 0.23 10.0 0.4 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF2668 PF10873.3 KFM01915.1 - 0.84 9.7 4.3 1.1 9.3 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) DUF3042 PF11240.3 KFM01915.1 - 1.6 8.5 4.6 3.2 7.6 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) LRR_8 PF13855.1 KFM01916.1 - 7.4e-32 108.9 25.4 1.7e-12 46.9 2.9 3.3 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KFM01916.1 - 1.2e-18 66.3 14.1 1.1e-07 31.2 0.4 4.5 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM01916.1 - 3.7e-14 50.5 16.0 0.013 15.3 0.0 7.5 7 0 0 7 7 7 4 Leucine Rich Repeat LRR_5 PF13306.1 KFM01916.1 - 7.3e-09 35.4 2.8 7.4e-09 35.3 0.1 2.1 1 1 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_7 PF13504.1 KFM01916.1 - 1.6e-05 24.3 15.9 0.34 11.2 0.2 6.5 6 0 0 6 6 6 2 Leucine rich repeat DUF3557 PF12078.3 KFM01916.1 - 0.0019 17.9 0.2 0.0048 16.6 0.0 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF3557) LRR_9 PF14580.1 KFM01916.1 - 0.0095 15.5 3.1 0.22 11.0 1.0 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRRNT PF01462.13 KFM01916.1 - 0.015 14.7 2.8 0.057 12.9 2.0 2.0 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain LRR_6 PF13516.1 KFM01916.1 - 0.13 12.4 22.2 0.26 11.4 0.1 6.1 6 1 1 7 7 7 0 Leucine Rich repeat LRR_3 PF07725.7 KFM01916.1 - 1.9 8.3 8.9 18 5.3 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich Repeat DUF643 PF04867.7 KFM01917.1 - 0.088 13.2 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF643) Abhydrolase_3 PF07859.8 KFM01918.1 - 1.4e-57 194.6 0.0 9.6e-45 152.7 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.23 KFM01918.1 - 8.9e-09 34.5 0.8 4.4e-08 32.2 0.5 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KFM01918.1 - 1.9e-06 27.7 0.0 2.8e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KFM01918.1 - 0.00044 18.9 0.0 0.00063 18.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Thioesterase PF00975.15 KFM01918.1 - 0.042 14.0 0.0 0.064 13.4 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Peptidase_S9 PF00326.16 KFM01918.1 - 0.05 12.8 0.0 0.088 12.0 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2920 PF11144.3 KFM01918.1 - 0.18 10.7 0.0 0.81 8.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Abhydrolase_3 PF07859.8 KFM01919.1 - 5.9e-53 179.5 0.0 6e-42 143.6 0.0 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.23 KFM01919.1 - 2.3e-08 33.2 0.5 1.3e-07 30.7 0.4 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KFM01919.1 - 0.00016 21.4 0.0 0.00025 20.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KFM01919.1 - 0.12 11.0 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Aconitase_C PF00694.14 KFM01919.1 - 0.18 11.9 0.0 0.29 11.2 0.0 1.2 1 0 0 1 1 1 0 Aconitase C-terminal domain Abhydrolase_3 PF07859.8 KFM01920.1 - 3.7e-49 167.1 0.0 3.6e-37 128.0 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFM01920.1 - 0.00057 19.6 0.0 0.00084 19.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KFM01920.1 - 0.0054 15.4 0.0 0.015 14.0 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family DUF2920 PF11144.3 KFM01920.1 - 0.035 13.1 0.0 2.1 7.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) EIF_2_alpha PF07541.7 KFM01920.1 - 0.057 13.1 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit DMA PF03474.9 KFM01920.1 - 0.15 11.9 0.1 0.54 10.1 0.0 1.9 2 0 0 2 2 2 0 DMRTA motif Abhydrolase_3 PF07859.8 KFM01921.1 - 1.1e-45 155.7 0.0 9.5e-33 113.5 0.0 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFM01921.1 - 9e-05 22.2 0.0 0.00012 21.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFM01921.1 - 0.00073 18.8 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.7 KFM01921.1 - 0.00085 17.9 0.0 0.0012 17.4 0.0 1.1 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 KFM01921.1 - 0.047 13.1 0.0 0.072 12.5 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase COesterase PF00135.23 KFM01921.1 - 0.058 12.0 0.5 0.83 8.2 0.3 2.1 1 1 0 1 1 1 0 Carboxylesterase family Thioesterase PF00975.15 KFM01921.1 - 0.082 13.1 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_3 PF07859.8 KFM01922.1 - 1.5e-50 171.7 0.1 1.8e-37 128.9 0.0 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFM01922.1 - 2.8e-07 30.3 0.0 3.8e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KFM01922.1 - 3.1e-05 22.9 0.2 0.00019 20.2 0.2 1.9 1 1 0 1 1 1 1 Carboxylesterase family DUF2424 PF10340.4 KFM01922.1 - 0.00028 19.6 0.0 0.00039 19.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) AXE1 PF05448.7 KFM01922.1 - 0.0058 15.1 0.0 0.0084 14.6 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 KFM01922.1 - 0.0068 15.6 0.0 0.017 14.3 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF2920 PF11144.3 KFM01922.1 - 0.0095 14.9 0.1 0.024 13.6 0.0 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF2920) Tex_N PF09371.5 KFM01922.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Tex-like protein N-terminal domain adh_short PF00106.20 KFM01923.1 - 4.6e-26 91.7 0.1 2.9e-25 89.1 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFM01923.1 - 5e-13 49.1 0.2 1.5e-12 47.5 0.1 1.7 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFM01923.1 - 9.6e-09 35.3 0.0 1.5e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 KFM01923.1 - 7.1e-07 28.4 0.0 9.8e-07 27.9 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 KFM01923.1 - 0.00042 20.4 0.2 0.00087 19.4 0.2 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 KFM01923.1 - 0.0072 15.7 0.1 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Hus1 PF04005.7 KFM01924.1 - 0.0017 17.3 0.0 0.0017 17.3 0.0 1.1 1 0 0 1 1 1 1 Hus1-like protein Ricin_B_lectin PF00652.17 KFM01925.1 - 0.012 15.6 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain TNFR_c6 PF00020.13 KFM01926.1 - 2.1e-12 46.8 50.5 1.3e-06 28.3 5.5 4.7 4 0 0 4 4 4 4 TNFR/NGFR cysteine-rich region GCC2_GCC3 PF07699.8 KFM01926.1 - 0.0006 19.3 2.3 0.0006 19.3 1.6 4.5 1 1 4 5 5 5 3 GCC2 and GCC3 TNFR_c6 PF00020.13 KFM01927.1 - 3.1e-07 30.3 43.2 0.0017 18.3 5.1 4.5 4 0 0 4 4 4 4 TNFR/NGFR cysteine-rich region Pox_P4A PF03395.9 KFM01927.1 - 0.021 12.3 0.2 0.056 10.9 0.0 1.6 2 0 0 2 2 2 0 Poxvirus P4A protein Fzo_mitofusin PF04799.8 KFM01929.1 - 4.7e-83 276.7 1.1 4.7e-83 276.7 0.8 3.1 3 0 0 3 3 3 1 fzo-like conserved region Dynamin_N PF00350.18 KFM01929.1 - 2e-23 83.0 0.0 2e-23 83.0 0.0 2.6 4 0 0 4 4 4 1 Dynamin family MMR_HSR1 PF01926.18 KFM01929.1 - 9.9e-07 28.7 0.0 4.8e-06 26.5 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Apolipoprotein PF01442.13 KFM01929.1 - 0.022 14.2 8.7 0.12 11.8 2.6 2.7 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain GTP_EFTU PF00009.22 KFM01929.1 - 0.079 12.3 0.4 0.59 9.5 0.2 2.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 KFM01929.1 - 0.1 12.1 0.0 0.33 10.5 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Synaptobrevin PF00957.16 KFM01929.1 - 0.15 11.6 2.4 0.4 10.3 0.1 2.5 2 0 0 2 2 2 0 Synaptobrevin 2OG-FeII_Oxy PF03171.15 KFM01930.1 - 4.4e-09 36.5 0.0 9.7e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Anp1 PF03452.9 KFM01930.1 - 1.3e-05 24.5 0.4 0.11 11.6 0.0 2.4 1 1 0 2 2 2 2 Anp1 DUF2152 PF10222.4 KFM01931.1 - 5.4e-190 632.6 0.0 6e-190 632.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2152) Guanylate_cyc PF00211.15 KFM01932.1 - 1e-68 230.3 0.0 1.2e-68 230.0 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.9 KFM01932.1 - 0.00046 19.4 0.8 0.00073 18.8 0.6 1.3 1 0 0 1 1 1 1 Heme NO binding associated DUF4377 PF14302.1 KFM01932.1 - 0.043 13.7 0.2 0.14 12.0 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4377) ANP PF00212.13 KFM01933.1 - 2.6e-15 56.1 5.3 5e-15 55.2 3.6 1.5 1 0 0 1 1 1 1 Atrial natriuretic peptide ANP PF00212.13 KFM01934.1 - 1.4e-13 50.6 9.7 2.4e-13 49.9 6.7 1.4 1 0 0 1 1 1 1 Atrial natriuretic peptide Voltage_CLC PF00654.15 KFM01935.1 - 1.6e-95 320.1 24.4 6.1e-95 318.2 12.5 2.1 1 1 1 2 2 2 2 Voltage gated chloride channel CBS PF00571.23 KFM01935.1 - 4.8e-15 55.0 0.2 3.3e-09 36.3 0.0 2.6 2 0 0 2 2 2 2 CBS domain MTHFR PF02219.12 KFM01936.1 - 4.4e-119 396.8 0.0 5.7e-119 396.4 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase AGTRAP PF06396.6 KFM01937.1 - 9.4e-47 158.7 4.6 1e-46 158.5 3.2 1.0 1 0 0 1 1 1 1 Angiotensin II, type I receptor-associated protein (AGTRAP) Draxin PF15550.1 KFM01938.1 - 5.9e-146 486.2 12.0 6.5e-146 486.1 8.3 1.0 1 0 0 1 1 1 1 Draxin HORMA PF02301.13 KFM01939.1 - 4.2e-25 88.4 0.1 5.6e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 HORMA domain FBA PF04300.8 KFM01940.1 - 3.2e-80 268.4 1.1 3.9e-80 268.1 0.8 1.1 1 0 0 1 1 1 1 F-box associated region F-box-like PF12937.2 KFM01940.1 - 1.4e-10 40.7 3.8 4.2e-10 39.1 2.6 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFM01940.1 - 3.3e-08 32.9 1.3 7.5e-08 31.8 0.9 1.7 1 0 0 1 1 1 1 F-box domain FBA PF04300.8 KFM01941.1 - 5.3e-85 284.0 1.1 6.3e-85 283.7 0.8 1.1 1 0 0 1 1 1 1 F-box associated region F-box PF00646.28 KFM01941.1 - 8.2e-10 38.0 0.8 1.4e-09 37.3 0.5 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KFM01941.1 - 4.5e-07 29.4 1.5 1e-06 28.3 1.0 1.7 1 0 0 1 1 1 1 F-box-like Patched PF02460.13 KFM01942.1 - 2.1e-23 82.2 25.9 1.2e-19 69.7 2.2 2.3 2 0 0 2 2 2 2 Patched family MMPL PF03176.10 KFM01942.1 - 2.4e-14 52.7 29.8 1.3e-09 37.2 3.7 2.3 2 0 0 2 2 2 2 MMPL family Sterol-sensing PF12349.3 KFM01942.1 - 5.6e-14 51.8 11.9 5.6e-14 51.8 8.2 2.8 2 1 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.14 KFM01942.1 - 0.0051 14.3 6.0 0.0095 13.3 4.2 1.3 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family DUF3049 PF11250.3 KFM01943.1 - 0.13 12.0 0.3 1.9 8.3 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3049) UbiA PF01040.13 KFM01944.1 - 2.3e-38 131.8 15.7 3e-38 131.5 10.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family FAT PF02259.18 KFM01945.1 - 2.5e-135 450.9 12.7 9.9e-134 445.7 8.6 3.1 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 KFM01945.1 - 3.1e-63 213.4 0.4 6.1e-63 212.4 0.3 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 KFM01945.1 - 1.9e-57 193.6 3.2 7.2e-57 191.7 0.1 3.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 KFM01945.1 - 1.2e-42 144.0 0.5 1.2e-42 144.0 0.3 3.8 5 0 0 5 5 4 1 Rapamycin binding domain HEAT_2 PF13646.1 KFM01945.1 - 3.9e-18 65.5 3.6 0.012 15.8 0.0 9.8 7 3 4 11 11 11 5 HEAT repeats FATC PF02260.15 KFM01945.1 - 5.8e-13 48.0 0.1 1.5e-12 46.6 0.1 1.8 1 0 0 1 1 1 1 FATC domain HEAT_EZ PF13513.1 KFM01945.1 - 1.9e-08 34.5 23.2 0.044 14.2 0.0 12.8 12 3 4 16 16 15 2 HEAT-like repeat HEAT PF02985.17 KFM01945.1 - 2.9e-06 26.8 18.4 19 5.6 0.0 13.2 15 0 0 15 15 13 0 HEAT repeat TPR_11 PF13414.1 KFM01945.1 - 0.00019 21.0 0.7 0.024 14.2 0.0 3.7 2 1 0 2 2 2 1 TPR repeat EPSP_synthase PF00275.15 KFM01945.1 - 0.016 13.6 0.0 0.027 12.8 0.0 1.3 1 0 0 1 1 1 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Apc3 PF12895.2 KFM01945.1 - 0.73 10.0 4.9 9.7 6.4 0.2 3.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 CFIA_Pcf11 PF11526.3 KFM01945.1 - 1.5 8.9 5.2 0.36 10.9 0.5 2.3 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 DNA_pol_A_exo1 PF01612.15 KFM01946.1 - 4.7e-49 166.2 2.1 9.8e-49 165.1 1.5 1.5 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 KFM01946.1 - 1.2e-28 99.2 0.1 2.7e-27 94.8 0.0 2.7 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.18 KFM01946.1 - 9.1e-14 50.9 0.4 2.1e-13 49.7 0.0 1.9 2 0 0 2 2 2 1 HRDC domain Spermine_synth PF01564.12 KFM01947.1 - 4.1e-64 215.8 0.0 6.2e-64 215.2 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 KFM01947.1 - 7.6e-06 25.5 0.0 8.8e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFM01947.1 - 0.0052 17.3 0.0 0.0099 16.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_30 PF05430.6 KFM01947.1 - 0.065 12.8 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Somatostatin PF03002.10 KFM01949.1 - 5.1e-12 45.0 7.6 7.2e-12 44.6 5.3 1.2 1 0 0 1 1 1 1 Somatostatin/Cortistatin family CUB PF00431.15 KFM01950.1 - 1e-18 67.3 0.1 1.5e-18 66.8 0.1 1.2 1 0 0 1 1 1 1 CUB domain EGF_CA PF07645.10 KFM01950.1 - 8.6e-08 32.0 7.0 1.8e-07 31.0 4.8 1.6 1 0 0 1 1 1 1 Calcium-binding EGF domain FXa_inhibition PF14670.1 KFM01950.1 - 1.1e-07 31.8 9.4 1.1e-07 31.8 6.5 1.7 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site cEGF PF12662.2 KFM01950.1 - 0.00084 18.9 4.5 0.00084 18.9 3.1 2.6 2 0 0 2 2 2 1 Complement Clr-like EGF-like EGF PF00008.22 KFM01950.1 - 0.0048 16.8 8.7 0.012 15.5 6.1 1.8 1 0 0 1 1 1 1 EGF-like domain RRM_1 PF00076.17 KFM01951.1 - 7.4e-30 102.3 0.2 1.1e-16 60.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM01951.1 - 1.6e-22 79.2 0.1 2.2e-10 40.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM01951.1 - 3e-08 33.3 0.7 0.00043 20.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFM01951.1 - 0.00039 20.2 0.0 0.076 12.8 0.0 2.4 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 KFM01951.1 - 0.031 14.0 0.0 0.97 9.2 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF4651 PF15513.1 KFM01951.1 - 0.075 12.4 0.0 3.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) Pex14_N PF04695.8 KFM01954.1 - 4.1e-24 85.1 0.3 4.1e-24 85.1 0.2 3.7 2 2 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF948 PF06103.6 KFM01954.1 - 0.021 14.6 1.4 0.046 13.5 0.9 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Nucleo_P87 PF07267.6 KFM01954.1 - 0.094 11.3 4.6 0.12 11.0 3.2 1.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 TMPIT PF07851.8 KFM01954.1 - 0.2 10.6 1.9 0.35 9.8 1.3 1.3 1 0 0 1 1 1 0 TMPIT-like protein CAF-1_p150 PF11600.3 KFM01954.1 - 0.31 10.3 10.7 0.69 9.2 7.4 1.6 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ribosomal_60s PF00428.14 KFM01954.1 - 2.8 8.3 6.3 1.2 9.5 2.4 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein DFF-C PF09033.5 KFM01955.1 - 2e-55 187.0 11.9 2e-55 187.0 8.3 2.1 2 0 0 2 2 2 1 DNA Fragmentation factor 45kDa, C terminal domain CIDE-N PF02017.10 KFM01955.1 - 2.4e-19 68.8 1.2 3.3e-17 62.0 0.0 3.0 3 0 0 3 3 3 1 CIDE-N domain DUF3610 PF12272.3 KFM01955.1 - 0.09 12.4 0.3 0.4 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3610) HR1 PF02185.11 KFM01955.1 - 0.33 10.7 13.0 0.75 9.5 2.3 2.8 2 1 0 2 2 2 0 Hr1 repeat DUF3192 PF11399.3 KFM01955.1 - 2 8.3 5.7 1.4 8.8 0.2 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF3192) COG2 PF06148.6 KFM01955.1 - 2.9 7.7 9.4 0.33 10.8 1.4 2.5 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Muted PF14942.1 KFM01955.1 - 8.8 6.1 9.4 2 8.3 2.3 2.4 2 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein CENP-S PF15630.1 KFM01956.1 - 1.7e-33 114.5 0.8 2.9e-33 113.8 0.5 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 KFM01956.1 - 0.0001 21.7 0.6 0.0001 21.7 0.4 1.9 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T Histone PF00125.19 KFM01956.1 - 0.00012 22.1 1.0 0.00015 21.8 0.2 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.10 KFM01956.1 - 0.00012 21.8 0.1 0.00015 21.5 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.8 KFM01956.1 - 0.0036 16.9 0.4 0.0076 15.9 0.1 1.7 2 0 0 2 2 2 1 Bromodomain associated RNA_pol_Rpc82 PF05645.8 KFM01956.1 - 0.0051 16.3 2.9 0.006 16.1 2.0 1.0 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 DUF3540 PF12059.3 KFM01956.1 - 0.036 13.7 0.9 0.041 13.5 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3540) BLVR PF06375.6 KFM01956.1 - 0.038 13.8 5.7 0.049 13.4 4.0 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) TFIID-18kDa PF02269.11 KFM01956.1 - 0.043 13.6 1.0 0.06 13.1 0.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Siah-Interact_N PF09032.6 KFM01956.1 - 0.093 12.7 3.3 0.17 11.9 2.3 1.5 1 0 0 1 1 1 0 Siah interacting protein, N terminal TAF PF02969.12 KFM01956.1 - 0.11 12.4 0.8 0.37 10.7 0.3 2.2 1 1 1 2 2 2 0 TATA box binding protein associated factor (TAF) 6PGD PF00393.14 KFM01957.1 - 1.4e-139 464.3 0.0 1.7e-139 463.9 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KFM01957.1 - 1.9e-51 174.1 0.0 2.7e-51 173.6 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KFM01957.1 - 0.011 15.8 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 KFM01957.1 - 0.11 12.9 0.1 0.27 11.6 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Kinesin PF00225.18 KFM01958.1 - 2e-117 391.6 0.7 3.2e-117 391.0 0.5 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 KFM01958.1 - 3e-44 150.0 0.0 6e-44 149.1 0.0 1.6 1 0 0 1 1 1 1 Kinesin protein PH PF00169.24 KFM01958.1 - 1.2e-14 54.3 0.1 1.4e-13 50.9 0.0 2.9 3 0 0 3 3 3 1 PH domain FHA PF00498.21 KFM01958.1 - 7e-08 32.4 0.2 3.3e-07 30.3 0.1 2.2 2 0 0 2 2 2 1 FHA domain KIF1B PF12423.3 KFM01958.1 - 1.9 8.5 6.2 0.24 11.4 0.2 2.4 2 0 0 2 2 2 0 Kinesin protein 1B Ufd2P_core PF10408.4 KFM01959.1 - 2.1e-184 614.3 13.5 3e-184 613.7 9.4 1.2 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 KFM01959.1 - 3e-26 91.1 1.1 7.5e-26 89.8 0.3 2.2 2 0 0 2 2 2 1 U-box domain Lipocalin PF00061.18 KFM01960.1 - 5.3e-12 45.9 0.1 6.2e-12 45.7 0.1 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Glyco_hydro_43 PF04616.9 KFM01960.1 - 0.096 11.7 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 43 CTP_transf_2 PF01467.21 KFM01961.1 - 3.5e-37 127.8 0.1 4.8e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase ICAT PF06384.6 KFM01962.1 - 6e-30 102.8 1.3 4.1e-29 100.1 0.0 2.4 2 1 0 2 2 2 1 Beta-catenin-interacting protein ICAT CAMP_factor PF07373.6 KFM01962.1 - 0.00016 21.3 0.5 0.0002 20.9 0.4 1.3 1 0 0 1 1 1 1 CAMP factor (Cfa) DUF3313 PF11769.3 KFM01962.1 - 0.0011 18.3 0.1 0.0019 17.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3313) DUF892 PF05974.7 KFM01962.1 - 0.0055 16.5 2.3 0.0055 16.5 1.6 1.7 2 0 0 2 2 1 1 Domain of unknown function (DUF892) GvpG PF05120.7 KFM01962.1 - 0.0059 16.3 9.3 0.011 15.5 0.1 2.4 2 0 0 2 2 2 1 Gas vesicle protein G ISG65-75 PF11727.3 KFM01962.1 - 0.0099 14.9 1.3 0.014 14.4 0.9 1.2 1 0 0 1 1 1 1 Invariant surface glycoprotein V_ATPase_I PF01496.14 KFM01962.1 - 0.041 11.7 2.2 0.042 11.7 1.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prominin PF05478.6 KFM01962.1 - 0.057 10.9 0.9 0.076 10.5 0.7 1.2 1 0 0 1 1 1 0 Prominin FlxA PF14282.1 KFM01962.1 - 0.06 13.3 10.2 0.058 13.3 5.1 2.1 1 1 1 2 2 2 0 FlxA-like protein NIT PF08376.5 KFM01962.1 - 0.06 12.8 0.5 0.06 12.8 0.3 2.0 1 1 1 2 2 2 0 Nitrate and nitrite sensing WXG100 PF06013.7 KFM01962.1 - 0.081 12.9 0.5 0.081 12.9 0.4 2.5 3 0 0 3 3 2 0 Proteins of 100 residues with WXG DMAP_binding PF06464.6 KFM01962.1 - 0.095 13.3 0.3 0.095 13.3 0.2 2.3 2 0 0 2 2 2 0 DMAP1-binding Domain CK2S PF15011.1 KFM01962.1 - 0.11 12.2 8.4 0.71 9.6 0.0 2.7 2 1 1 3 3 3 0 Casein Kinase 2 substrate DUF4254 PF14063.1 KFM01962.1 - 0.14 11.7 3.4 0.27 10.8 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4254) EAP30 PF04157.11 KFM01962.1 - 0.16 11.0 5.8 0.22 10.6 3.5 1.6 1 1 0 1 1 1 0 EAP30/Vps36 family GrpE PF01025.14 KFM01962.1 - 0.18 11.3 3.7 0.26 10.8 2.6 1.3 1 0 0 1 1 1 0 GrpE DUF1098 PF06497.6 KFM01962.1 - 0.19 11.8 2.3 0.2 11.7 0.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1098) Laminin_II PF06009.7 KFM01962.1 - 0.22 11.2 5.4 1.6 8.4 0.6 2.5 1 1 1 2 2 2 0 Laminin Domain II Cauli_AT PF03233.8 KFM01962.1 - 0.25 11.0 3.1 0.48 10.1 2.2 1.4 1 0 0 1 1 1 0 Aphid transmission protein DUF148 PF02520.12 KFM01962.1 - 0.4 10.4 4.7 2.5 7.9 3.2 2.1 1 1 0 1 1 1 0 Domain of unknown function DUF148 APG6 PF04111.7 KFM01962.1 - 0.4 9.6 6.5 0.48 9.4 4.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Allexi_40kDa PF05549.6 KFM01962.1 - 0.5 9.6 3.4 0.67 9.1 2.1 1.4 1 1 0 1 1 1 0 Allexivirus 40kDa protein IncA PF04156.9 KFM01962.1 - 0.64 9.5 14.0 0.92 9.0 9.6 1.4 1 1 0 1 1 1 0 IncA protein NPV_P10 PF05531.7 KFM01962.1 - 0.74 10.0 5.2 1.1 9.5 2.5 2.2 2 1 0 2 2 1 0 Nucleopolyhedrovirus P10 protein Baculo_p24 PF05073.7 KFM01962.1 - 1 8.8 4.6 8.2 5.9 1.7 2.0 1 1 1 2 2 2 0 Baculovirus P24 capsid protein DUF883 PF05957.8 KFM01962.1 - 1.1 9.7 4.8 2.3 8.6 0.8 2.6 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF2408 PF10303.4 KFM01962.1 - 1.3 9.1 7.4 2.1 8.4 3.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) DUF948 PF06103.6 KFM01962.1 - 2 8.3 5.0 18 5.2 1.6 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) AAA_23 PF13476.1 KFM01962.1 - 3.3 7.9 9.0 6.9 6.9 6.3 1.5 1 0 0 1 1 1 0 AAA domain CorA PF01544.13 KFM01962.1 - 3.8 6.4 7.8 5.7 5.8 4.5 1.8 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Syntaxin-6_N PF09177.6 KFM01962.1 - 4.1 7.8 7.6 7.3 7.0 3.6 2.3 1 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF342 PF03961.8 KFM01962.1 - 6.6 5.0 7.9 8.1 4.7 5.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) MerR-DNA-bind PF09278.6 KFM01962.1 - 8.5 6.8 10.5 0.38 11.1 1.9 2.6 3 0 0 3 3 2 0 MerR, DNA binding ICAT PF06384.6 KFM01963.1 - 5.7e-28 96.5 0.1 6.2e-28 96.4 0.1 1.0 1 0 0 1 1 1 1 Beta-catenin-interacting protein ICAT DUF3140 PF11338.3 KFM01963.1 - 0.044 13.9 0.0 0.047 13.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) Cadherin PF00028.12 KFM01964.1 - 3.7e-15 55.9 0.0 4.9e-07 29.9 0.0 2.8 2 0 0 2 2 2 2 Cadherin domain Laminin_G_3 PF13385.1 KFM01964.1 - 8.6e-09 35.8 0.0 1.6e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily CDC45 PF02724.9 KFM01964.1 - 0.00059 18.0 3.2 0.00079 17.5 2.2 1.1 1 0 0 1 1 1 1 CDC45-like protein Glyco_hydro_16 PF00722.16 KFM01964.1 - 0.0039 16.5 0.4 0.013 14.7 0.1 1.9 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 DUF1510 PF07423.6 KFM01964.1 - 0.017 14.4 11.6 0.029 13.7 8.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Laminin_G_2 PF02210.19 KFM01964.1 - 0.02 14.9 0.0 0.094 12.7 0.0 2.2 2 0 0 2 2 2 0 Laminin G domain SID-1_RNA_chan PF13965.1 KFM01964.1 - 0.025 12.7 0.7 0.037 12.2 0.5 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 EphA2_TM PF14575.1 KFM01964.1 - 0.082 13.3 0.1 0.67 10.3 0.0 2.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Ycf1 PF05758.7 KFM01964.1 - 0.14 9.8 0.7 0.19 9.3 0.5 1.1 1 0 0 1 1 1 0 Ycf1 PI3_PI4_kinase PF00454.22 KFM01965.1 - 3.1e-56 190.4 0.1 7.6e-56 189.2 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 KFM01965.1 - 7e-56 188.3 4.3 1.3e-55 187.4 3.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_p85B PF02192.11 KFM01965.1 - 1.7e-35 120.2 0.0 4.7e-35 118.8 0.0 1.8 1 0 0 1 1 1 1 PI3-kinase family, p85-binding domain PI3K_C2 PF00792.19 KFM01965.1 - 4.9e-34 117.1 0.1 1.6e-33 115.5 0.0 1.9 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.13 KFM01965.1 - 4.7e-25 87.6 0.0 2.2e-24 85.4 0.0 2.2 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain TpcC PF12642.2 KFM01965.1 - 0.13 11.7 0.1 0.27 10.7 0.1 1.4 1 0 0 1 1 1 0 Conjugative transposon protein TcpC DUF2448 PF10476.4 KFM01966.1 - 4.1e-77 258.3 0.6 6.2e-77 257.7 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2448) Ima1_N PF09779.4 KFM01966.1 - 1.3e-36 125.9 10.8 2.7e-36 124.9 7.5 1.6 1 0 0 1 1 1 1 Ima1 N-terminal domain Zn_Tnp_IS1 PF03811.8 KFM01966.1 - 2.2 7.8 10.4 1.4 8.5 0.5 3.6 3 0 0 3 3 3 0 InsA N-terminal domain Mito_carr PF00153.22 KFM01967.1 - 2.2e-64 213.2 2.7 3.7e-21 74.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SPRY PF00622.23 KFM01968.1 - 7.6e-18 64.7 0.0 1.1e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 SPRY domain SOCS_box PF07525.11 KFM01968.1 - 9.5e-15 54.1 2.6 1.7e-14 53.3 1.8 1.5 1 0 0 1 1 1 1 SOCS box Glucosamine_iso PF01182.15 KFM01969.1 - 7e-56 189.0 0.0 1.5e-55 187.9 0.0 1.6 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase G6PD_C PF02781.11 KFM01969.1 - 5.3e-45 153.5 0.0 1.9e-38 132.0 0.0 2.1 2 0 0 2 2 2 2 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 KFM01969.1 - 1.6e-38 132.7 0.0 7.4e-38 130.6 0.0 2.1 3 0 0 3 3 3 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Sugar_tr PF00083.19 KFM01970.1 - 9.2e-128 426.6 25.0 1e-127 426.4 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFM01970.1 - 6e-19 67.9 52.7 1.2e-17 63.7 17.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Carb_anhydrase PF00194.16 KFM01971.1 - 8.9e-81 270.6 0.0 1.2e-80 270.1 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Pentaxin PF00354.12 KFM01971.1 - 3.4e-40 137.5 0.1 5.3e-40 136.9 0.0 1.3 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.1 KFM01971.1 - 2.4e-10 40.8 0.9 4.4e-10 40.0 0.6 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Enolase_C PF00113.17 KFM01972.1 - 3.5e-160 531.7 0.0 4.6e-160 531.3 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 KFM01972.1 - 1.5e-58 196.4 0.1 2.4e-58 195.7 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 KFM01972.1 - 0.00014 21.7 0.0 0.00032 20.6 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.6 KFM01972.1 - 0.0011 17.9 0.2 0.0026 16.7 0.1 1.6 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus BTB PF00651.26 KFM01974.1 - 3.8e-24 84.8 0.1 1.1e-23 83.3 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain zf-H2C2_2 PF13465.1 KFM01974.1 - 4.4e-22 77.2 37.6 2.1e-06 27.7 1.9 6.9 6 1 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.21 KFM01974.1 - 9.5e-22 75.9 41.3 1.9e-06 27.8 1.5 6.2 6 0 0 6 6 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM01974.1 - 2.3e-15 55.7 32.0 0.00034 20.7 1.0 5.8 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.2 KFM01974.1 - 2.3e-07 30.7 33.4 0.0025 17.9 1.0 5.9 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFM01974.1 - 5.9e-07 29.1 19.5 0.01 15.7 0.2 5.7 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KFM01974.1 - 8.9e-06 25.2 6.3 0.46 10.2 0.0 4.5 4 0 0 4 4 4 3 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 KFM01974.1 - 0.0002 21.4 20.6 0.073 13.2 0.4 4.6 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFM01974.1 - 0.0024 17.9 24.1 0.027 14.5 6.7 4.4 2 1 1 3 3 3 2 C2H2 type zinc-finger (2 copies) BolA PF01722.13 KFM01974.1 - 0.022 14.7 1.4 0.91 9.5 0.2 3.4 3 1 0 3 3 3 0 BolA-like protein zf-Di19 PF05605.7 KFM01974.1 - 0.093 12.8 22.8 1.8 8.7 2.5 4.1 2 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-Sec23_Sec24 PF04810.10 KFM01974.1 - 1.1 8.8 10.4 1.9 8.1 0.0 4.3 5 0 0 5 5 5 0 Sec23/Sec24 zinc finger DUF2225 PF09986.4 KFM01974.1 - 1.5 8.2 13.0 1 8.7 0.2 3.9 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) Endonuclease_7 PF02945.10 KFM01974.1 - 3.6 7.3 13.0 1.3 8.7 3.1 3.6 1 1 1 2 2 2 0 Recombination endonuclease VII 7tm_1 PF00001.16 KFM01976.1 - 7e-86 287.5 14.0 9.7e-86 287.0 9.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM01976.1 - 3.4e-10 39.5 18.1 8.9e-08 31.5 10.6 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM01976.1 - 0.0064 15.6 16.9 0.0085 15.2 11.0 1.7 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx TGT PF01702.13 KFM01977.1 - 7.4e-69 231.6 0.0 8.9e-69 231.3 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase zf-DHHC PF01529.15 KFM01979.1 - 3.9e-35 120.7 0.8 3.9e-35 120.7 0.6 2.2 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF389 PF04087.9 KFM01979.1 - 0.27 11.1 4.3 1.3 8.9 2.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF389) GRAM PF02893.15 KFM01980.1 - 5.3e-19 67.5 0.4 2.3e-18 65.4 0.0 2.3 3 0 0 3 3 3 1 GRAM domain TarH PF02203.10 KFM01980.1 - 0.026 14.3 0.2 0.055 13.2 0.2 1.6 1 0 0 1 1 1 0 Tar ligand binding domain homologue V-set PF07686.12 KFM01981.1 - 1e-16 60.8 0.0 1.3e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 KFM01981.1 - 1.2e-08 34.9 0.0 2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 KFM01981.1 - 1.2e-08 34.6 0.0 2.4e-08 33.7 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 KFM01981.1 - 7.6e-07 29.1 0.0 5.4e-06 26.4 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin domain V-set_CD47 PF08204.6 KFM01981.1 - 7.4e-05 22.5 0.0 0.0001 22.0 0.0 1.1 1 0 0 1 1 1 1 CD47 immunoglobulin-like domain Ig_3 PF13927.1 KFM01981.1 - 0.00086 19.7 0.0 0.0016 18.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain DUF3872 PF12988.2 KFM01981.1 - 0.0041 16.6 0.0 0.006 16.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function, B. Theta Gene description (DUF3872) Receptor_2B4 PF11465.3 KFM01981.1 - 0.036 13.9 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 Herpes_gE PF02480.11 KFM01981.1 - 0.037 12.3 0.4 0.2 9.8 0.0 2.0 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E DUF4035 PF13227.1 KFM01981.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4035) Phospholip_A2_1 PF00068.14 KFM01982.1 - 4e-34 117.3 15.3 4.7e-34 117.0 10.6 1.2 1 0 0 1 1 1 1 Phospholipase A2 Parvo_coat_N PF08398.5 KFM01982.1 - 0.003 17.3 0.0 0.0044 16.7 0.0 1.3 1 0 0 1 1 1 1 Parvovirus coat protein VP1 Claudin_2 PF13903.1 KFM01983.1 - 8.5e-19 67.8 0.0 1.4e-18 67.1 0.0 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 KFM01983.1 - 3.1e-09 36.6 5.6 6.8e-07 29.0 0.7 2.4 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin family TMEM190 PF15431.1 KFM01983.1 - 0.13 12.1 0.2 0.13 12.1 0.1 1.7 2 0 0 2 2 2 0 Transmembrane protein 190 Apo-VLDL-II PF05418.6 KFM01984.1 - 1.5e-48 162.8 0.4 1.9e-48 162.5 0.3 1.1 1 0 0 1 1 1 1 Apovitellenin I (Apo-VLDL-II) LSR PF05624.9 KFM01985.1 - 1.2e-19 69.7 34.5 1.9e-19 69.1 23.9 1.3 1 0 0 1 1 1 1 Lipolysis stimulated receptor (LSR) V-set PF07686.12 KFM01985.1 - 0.003 17.4 2.2 0.017 14.9 0.0 2.9 2 1 0 2 2 2 1 Immunoglobulin V-set domain I-set PF07679.11 KFM01985.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin I-set domain WD40 PF00400.27 KFM01986.1 - 3.3e-20 71.1 3.8 0.00084 19.1 0.0 7.8 8 0 0 8 8 8 5 WD domain, G-beta repeat PQQ_3 PF13570.1 KFM01986.1 - 0.01 16.0 0.2 2.9 8.2 0.0 3.8 4 0 0 4 4 4 0 PQQ-like domain RNA_polI_A14 PF08203.6 KFM01987.1 - 0.72 10.1 3.4 0.85 9.9 0.2 2.6 2 1 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 CENP-B_dimeris PF09026.5 KFM01987.1 - 2.7 8.2 10.5 22 5.3 5.8 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain I-set PF07679.11 KFM01988.1 - 2.6e-47 158.6 0.0 3.5e-17 62.0 0.0 5.0 5 0 0 5 5 5 4 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM01988.1 - 4.9e-40 135.5 0.0 2.4e-11 43.5 0.0 4.5 4 0 0 4 4 4 4 Immunoglobulin domain fn3 PF00041.16 KFM01988.1 - 4.5e-36 122.8 0.4 1.5e-12 47.4 0.0 3.5 3 0 0 3 3 3 3 Fibronectin type III domain ig PF00047.20 KFM01988.1 - 3.1e-26 91.2 0.0 3.5e-07 30.2 0.0 5.2 5 0 0 5 5 5 4 Immunoglobulin domain Ig_3 PF13927.1 KFM01988.1 - 2.4e-21 75.9 0.2 2.5e-07 31.0 0.1 4.8 4 0 0 4 4 4 2 Immunoglobulin domain V-set PF07686.12 KFM01988.1 - 8.4e-14 51.4 1.7 0.00039 20.3 0.0 6.2 3 2 1 4 4 4 3 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM01988.1 - 9.7e-11 41.4 1.1 0.01 15.7 0.0 4.4 4 0 0 4 4 4 3 CD80-like C2-set immunoglobulin domain C1-set PF07654.10 KFM01988.1 - 1.6e-05 24.8 0.1 1.2 9.2 0.0 4.4 3 1 0 3 3 3 2 Immunoglobulin C1-set domain BiPBP_C PF06832.7 KFM01988.1 - 3.3e-05 23.7 0.0 0.36 10.7 0.0 4.0 3 0 0 3 3 3 1 Penicillin-Binding Protein C-terminus Family C2-set PF05790.10 KFM01988.1 - 0.016 15.1 0.0 20 5.2 0.0 3.6 3 0 0 3 3 3 0 Immunoglobulin C2-set domain CD34_antigen PF06365.7 KFM01988.1 - 0.37 10.4 0.9 0.53 9.9 0.0 1.6 2 0 0 2 2 2 0 CD34/Podocalyxin family DUF4477 PF14780.1 KFM01989.1 - 1.8e-45 154.6 6.4 1.8e-45 154.6 4.5 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4477) TFIID-18kDa PF02269.11 KFM01990.1 - 2e-38 130.0 0.4 2.4e-38 129.8 0.3 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit GTP_EFTU_D2 PF03144.20 KFM01990.1 - 0.075 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KFM01991.1 - 2.1e-08 34.1 0.0 1.3e-07 31.6 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFM01991.1 - 1.5e-06 27.8 0.0 0.00026 20.4 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KFM01991.1 - 0.0034 17.5 0.0 0.0056 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 KFM01991.1 - 0.0041 17.5 0.0 0.044 14.2 0.0 2.2 2 1 0 2 2 2 1 Miro-like protein FeoB_N PF02421.13 KFM01991.1 - 0.006 15.8 0.0 0.34 10.1 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_21 PF13304.1 KFM01991.1 - 0.01 15.8 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KFM01991.1 - 0.011 14.9 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 KFM01991.1 - 0.022 14.4 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 KFM01991.1 - 0.029 13.8 0.0 2.5 7.5 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 KFM01991.1 - 0.079 12.8 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KFM01991.1 - 0.1 12.6 0.3 0.42 10.5 0.0 1.8 1 1 1 2 2 2 0 AAA ATPase domain ATP_bind_1 PF03029.12 KFM01991.1 - 0.14 11.6 0.0 1.2 8.5 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein V-set PF07686.12 KFM01992.1 - 2.6e-08 33.7 0.4 7.6e-08 32.2 0.1 1.8 2 0 0 2 2 2 1 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM01992.1 - 1.6e-06 27.9 0.3 3.8e-06 26.7 0.2 1.7 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain I-set PF07679.11 KFM01992.1 - 9.4e-06 25.3 0.4 0.0048 16.7 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM01992.1 - 0.00033 20.7 6.3 0.033 14.3 0.3 2.4 1 1 1 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 KFM01992.1 - 0.00056 20.3 5.6 0.39 11.2 0.5 3.6 2 2 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 KFM01992.1 - 0.00064 19.7 2.1 0.011 15.8 0.2 2.6 2 1 0 2 2 2 1 Immunoglobulin domain C1-set PF07654.10 KFM01992.1 - 0.44 10.5 3.3 1.7 8.6 0.2 2.6 2 1 1 3 3 3 0 Immunoglobulin C1-set domain V-set PF07686.12 KFM01993.1 - 2.6e-08 33.7 0.4 7.6e-08 32.2 0.1 1.8 2 0 0 2 2 2 1 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM01993.1 - 1.6e-06 27.9 0.3 3.8e-06 26.7 0.2 1.7 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain I-set PF07679.11 KFM01993.1 - 9.4e-06 25.3 0.4 0.0048 16.7 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM01993.1 - 0.00033 20.7 6.3 0.033 14.3 0.3 2.4 1 1 1 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 KFM01993.1 - 0.00056 20.3 5.6 0.39 11.2 0.5 3.6 2 2 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 KFM01993.1 - 0.00064 19.7 2.1 0.011 15.8 0.2 2.6 2 1 0 2 2 2 1 Immunoglobulin domain C1-set PF07654.10 KFM01993.1 - 0.44 10.5 3.3 1.7 8.6 0.2 2.6 2 1 1 3 3 3 0 Immunoglobulin C1-set domain DUF4174 PF13778.1 KFM01994.1 - 4.2e-89 294.5 0.2 1.3e-34 118.7 0.0 3.4 3 0 0 3 3 3 3 Domain of unknown function (DUF4174) DUF2570 PF10828.3 KFM01994.1 - 0.018 14.6 0.0 0.052 13.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Nuc_sug_transp PF04142.10 KFM01995.1 - 1.8e-80 269.5 6.1 2.5e-80 269.1 4.2 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 KFM01995.1 - 1.5e-06 28.2 5.5 1.5e-06 28.2 3.8 3.1 3 1 0 3 3 3 1 EamA-like transporter family UAA PF08449.6 KFM01995.1 - 3.5e-06 26.1 14.5 8.6e-06 24.8 10.1 1.6 1 1 0 1 1 1 1 UAA transporter family EmrE PF13536.1 KFM01995.1 - 0.0079 16.3 7.9 0.0079 16.3 5.5 2.8 2 1 0 2 2 2 1 Multidrug resistance efflux transporter TPT PF03151.11 KFM01995.1 - 4.5 6.9 25.6 0.037 13.6 5.3 3.7 2 1 0 2 2 2 0 Triose-phosphate Transporter family Autophagy_N PF03986.8 KFM01996.1 - 1.7e-48 164.1 2.0 1.9e-48 163.9 0.9 1.5 1 1 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 KFM01996.1 - 5.7e-26 90.4 4.4 1.3e-25 89.3 3.0 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 KFM01996.1 - 8.2e-16 56.8 0.7 1.5e-15 55.9 0.5 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal F5_F8_type_C PF00754.20 KFM01997.1 - 6.6e-55 184.4 9.4 6.2e-28 97.2 1.0 3.1 3 0 0 3 3 3 2 F5/8 type C domain Cu-oxidase_3 PF07732.10 KFM01997.1 - 3e-30 104.3 0.8 5.7e-09 35.7 0.0 5.9 5 1 0 5 5 5 4 Multicopper oxidase Cu-oxidase_2 PF07731.9 KFM01997.1 - 1.9e-10 40.4 4.1 0.00014 21.4 0.1 5.8 5 1 0 5 5 5 3 Multicopper oxidase Folate_carrier PF01770.13 KFM01998.1 - 3.6e-172 572.5 25.9 4.3e-172 572.2 17.9 1.1 1 0 0 1 1 1 1 Reduced folate carrier MFS_1 PF07690.11 KFM01998.1 - 6.3e-09 35.0 21.0 6.3e-09 35.0 14.5 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DASH_Hsk3 PF08227.6 KFM02000.1 - 1.1e-15 57.5 1.4 2.1e-15 56.6 0.2 2.2 2 0 0 2 2 2 1 DASH complex subunit Hsk3 like MbeD_MobD PF04899.7 KFM02000.1 - 4 7.4 9.9 1.2 9.0 0.4 3.1 1 1 2 3 3 3 0 MbeD/MobD like DivIVA PF05103.8 KFM02000.1 - 7.4 6.6 14.2 1.2 9.1 2.3 2.4 2 0 0 2 2 2 0 DivIVA protein NDK PF00334.14 KFM02001.1 - 2.3e-71 237.8 0.0 8.3e-40 135.7 0.0 2.1 2 0 0 2 2 2 2 Nucleoside diphosphate kinase DERM PF14704.1 KFM02002.1 - 3.9e-34 117.8 4.0 4.8e-34 117.5 2.8 1.1 1 0 0 1 1 1 1 Dermatopontin IL8 PF00048.15 KFM02003.1 - 3e-12 46.3 0.7 3.6e-12 46.0 0.5 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like ChitinaseA_N PF08329.5 KFM02003.1 - 0.069 12.9 0.0 0.075 12.8 0.0 1.0 1 0 0 1 1 1 0 Chitinase A, N-terminal domain Oxidored_q1 PF00361.15 KFM02003.1 - 0.14 11.4 0.0 0.14 11.4 0.0 1.0 1 0 0 1 1 1 0 NADH-Ubiquinone/plastoquinone (complex I), various chains T-box PF00907.17 KFM02004.1 - 8.2e-82 273.1 0.0 1.1e-81 272.7 0.0 1.1 1 0 0 1 1 1 1 T-box Got1 PF04178.7 KFM02005.1 - 4.8e-31 107.3 13.5 6.3e-31 106.9 9.3 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family PTR2 PF00854.16 KFM02005.1 - 0.013 14.3 3.3 0.014 14.1 2.3 1.1 1 0 0 1 1 1 0 POT family FA_desaturase PF00487.19 KFM02005.1 - 1.4 8.2 7.4 1.7 7.9 5.1 1.2 1 0 0 1 1 1 0 Fatty acid desaturase DUF1212 PF06738.7 KFM02005.1 - 1.5 8.2 4.8 0.85 9.0 2.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1212) PGG PF13962.1 KFM02005.1 - 2.1 7.9 6.4 0.59 9.7 0.9 2.2 1 1 1 2 2 2 0 Domain of unknown function PhaG_MnhG_YufB PF03334.9 KFM02005.1 - 3.2 7.8 8.7 15 5.7 6.0 2.0 1 1 0 1 1 1 0 Na+/H+ antiporter subunit DUF998 PF06197.8 KFM02005.1 - 3.8 6.7 13.6 9.4 5.5 9.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF998) DUF2244 PF10003.4 KFM02005.1 - 5.6 6.3 14.0 0.56 9.5 3.6 2.1 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) TIP41 PF04176.8 KFM02006.1 - 1.8e-74 248.9 0.6 2e-74 248.7 0.4 1.0 1 0 0 1 1 1 1 TIP41-like family 7tm_1 PF00001.16 KFM02007.1 - 2.8e-46 157.7 19.8 2.8e-46 157.7 13.7 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 KFM02007.1 - 0.00032 19.9 19.3 0.00046 19.3 13.1 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx EXOSC1 PF10447.4 KFM02007.1 - 0.12 12.3 0.2 0.28 11.1 0.1 1.6 1 0 0 1 1 1 0 Exosome component EXOSC1/CSL4 Serpentine_r_xa PF03383.10 KFM02007.1 - 2.5 7.8 11.5 0.35 10.6 1.9 2.3 2 0 0 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa SNF2_N PF00176.18 KFM02008.1 - 2.1e-81 273.0 0.6 3.4e-81 272.3 0.4 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFM02008.1 - 5.4e-11 42.1 0.0 1.3e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-GRF PF06839.7 KFM02008.1 - 9.4e-06 25.4 4.0 6.9e-05 22.6 0.1 3.2 3 0 0 3 3 3 1 GRF zinc finger ResIII PF04851.10 KFM02008.1 - 0.0004 20.2 0.0 0.0014 18.5 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Coprogen_oxidas PF01218.13 KFM02009.1 - 2.8e-124 413.4 0.0 3.1e-124 413.3 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Glyco_transf_29 PF00777.13 KFM02010.1 - 2.1e-71 240.2 0.0 2.6e-71 239.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) C1q PF00386.16 KFM02011.1 - 5.6e-37 126.5 0.1 6.8e-37 126.3 0.1 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 KFM02011.1 - 2.9e-25 87.5 95.4 5.8e-08 32.1 16.1 4.0 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) F5_F8_type_C PF00754.20 KFM02012.1 - 5e-27 94.2 0.5 9.3e-27 93.4 0.3 1.5 1 0 0 1 1 1 1 F5/8 type C domain CUB PF00431.15 KFM02012.1 - 2.8e-25 88.5 0.0 5e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 CUB domain LCCL PF03815.14 KFM02012.1 - 9.1e-18 64.0 0.1 2.3e-17 62.7 0.1 1.6 1 0 0 1 1 1 1 LCCL domain Syndecan PF01034.15 KFM02012.1 - 0.069 12.8 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Syndecan domain Sex_peptide PF08138.6 KFM02012.1 - 0.073 12.9 0.1 0.22 11.3 0.1 1.8 1 0 0 1 1 1 0 Sex peptide (SP) family CDC50 PF03381.10 KFM02013.1 - 2.6e-85 285.9 2.9 3.5e-85 285.5 2.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family CMS1 PF14617.1 KFM02014.1 - 1e-27 96.8 1.2 2.4e-27 95.5 0.8 1.6 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 KFM02014.1 - 2.6e-05 23.7 0.0 5.8e-05 22.6 0.0 1.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase CortBP2 PF09727.4 KFM02015.1 - 7e-78 260.5 27.6 7e-78 260.5 19.1 6.9 2 2 4 6 6 6 2 Cortactin-binding protein-2 DMPK_coil PF08826.5 KFM02015.1 - 0.011 15.5 2.5 0.011 15.5 1.8 12.4 5 4 4 11 11 11 0 DMPK coiled coil domain like CN_hydrolase PF00795.17 KFM02016.1 - 7.2e-35 120.0 0.0 9.8e-35 119.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TPR_11 PF13414.1 KFM02017.1 - 3.4e-50 167.5 27.5 1.8e-19 69.1 1.5 6.7 5 2 2 7 7 7 7 TPR repeat TPR_1 PF00515.23 KFM02017.1 - 1.8e-37 125.4 25.7 1.6e-08 33.8 0.6 10.1 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.12 KFM02017.1 - 4.6e-32 107.3 25.5 6.1e-06 25.7 0.1 10.7 11 0 0 11 11 10 7 Tetratricopeptide repeat TPR_14 PF13428.1 KFM02017.1 - 5.5e-21 73.1 9.3 0.0024 18.3 0.0 8.4 5 2 4 9 9 8 6 Tetratricopeptide repeat TPR_8 PF13181.1 KFM02017.1 - 5.4e-20 69.6 19.1 0.0087 15.7 0.0 10.0 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.1 KFM02017.1 - 5.5e-19 67.8 19.4 0.0015 18.3 0.0 6.8 4 2 3 8 8 8 6 Tetratricopeptide repeat TPR_17 PF13431.1 KFM02017.1 - 7e-17 60.1 14.5 0.007 16.4 0.0 9.7 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFM02017.1 - 1.7e-16 60.4 9.1 0.0064 17.1 0.0 6.8 5 2 2 7 7 6 4 Tetratricopeptide repeat TPR_6 PF13174.1 KFM02017.1 - 2.8e-12 46.2 10.1 1.6 9.3 0.0 9.2 10 1 0 10 10 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFM02017.1 - 1.2e-11 44.8 16.4 0.005 17.1 0.0 6.7 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 KFM02017.1 - 1.5e-11 44.0 4.3 0.0019 18.0 0.4 6.1 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFM02017.1 - 3.3e-10 38.9 3.5 0.023 14.4 0.0 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat Apc3 PF12895.2 KFM02017.1 - 6.2e-07 29.4 25.1 0.041 14.0 3.0 5.7 5 1 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 KFM02017.1 - 4e-06 26.5 9.1 0.0086 15.9 0.9 4.2 3 2 0 3 3 2 2 MIT (microtubule interacting and transport) domain TPR_15 PF13429.1 KFM02017.1 - 6.4e-05 22.1 10.6 0.97 8.4 0.2 5.8 3 3 4 7 7 7 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 KFM02017.1 - 0.0076 16.0 2.2 0.61 9.8 0.0 3.9 4 0 0 4 4 3 1 Mad3/BUB1 homology region 1 MAS20 PF02064.10 KFM02017.1 - 0.016 15.1 0.4 5.6 6.8 0.0 3.5 3 0 0 3 3 3 0 MAS20 protein import receptor PPR PF01535.15 KFM02017.1 - 0.02 14.8 0.4 6.4 6.9 0.0 3.6 3 0 0 3 3 2 0 PPR repeat RPN7 PF10602.4 KFM02017.1 - 0.023 14.0 0.5 0.023 14.0 0.3 3.5 4 1 0 4 4 4 0 26S proteasome subunit RPN7 SHNi-TPR PF10516.4 KFM02017.1 - 5.3 6.3 7.2 8.3 5.7 0.0 4.0 5 0 0 5 5 5 0 SHNi-TPR LNP1 PF15419.1 KFM02018.1 - 4.6e-54 183.1 18.8 5.4e-54 182.9 13.1 1.0 1 0 0 1 1 1 1 Leukemia NUP98 fusion partner 1 TIP120 PF08623.5 KFM02018.1 - 0.078 12.5 0.1 0.097 12.2 0.0 1.1 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) DUF716 PF04819.7 KFM02019.1 - 1.1e-44 151.1 11.2 1.9e-44 150.4 7.8 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF716) 7tm_2 PF00002.19 KFM02020.1 - 4.3e-39 134.0 15.2 6.7e-39 133.4 10.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.16 KFM02020.1 - 4.3e-11 42.7 4.1 9.3e-11 41.6 2.8 1.5 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain EGF PF00008.22 KFM02020.1 - 0.15 12.0 4.4 0.39 10.7 3.0 1.7 1 0 0 1 1 1 0 EGF-like domain DUF4131 PF13567.1 KFM02020.1 - 2.4 7.5 10.8 0.16 11.3 0.3 3.4 2 1 2 4 4 4 0 Domain of unknown function (DUF4131) EGF_2 PF07974.8 KFM02020.1 - 9.3 6.5 16.8 0.099 12.8 6.2 1.8 2 0 0 2 2 2 0 EGF-like domain PB1 PF00564.19 KFM02021.1 - 1.5e-16 59.8 0.3 3.5e-16 58.6 0.2 1.7 2 0 0 2 2 2 1 PB1 domain DUF605 PF04652.11 KFM02021.1 - 0.53 9.6 13.0 0.61 9.4 9.0 1.1 1 0 0 1 1 1 0 Vta1 like SEA PF01390.15 KFM02022.1 - 8.5e-38 128.3 3.1 5.2e-20 71.1 0.3 2.8 2 0 0 2 2 2 2 SEA domain EGF PF00008.22 KFM02022.1 - 0.0026 17.6 12.1 0.0032 17.4 3.2 2.5 2 0 0 2 2 2 2 EGF-like domain Arb2 PF09757.4 KFM02023.1 - 4.9e-23 81.4 1.0 2.3e-22 79.3 0.1 2.3 2 1 0 2 2 2 1 Arb2 domain Abhydrolase_6 PF12697.2 KFM02023.1 - 0.036 13.9 0.0 0.05 13.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.9 KFM02023.1 - 0.073 12.3 0.3 12 5.0 0.0 2.5 3 0 0 3 3 3 0 Putative serine esterase (DUF676) DIM1 PF02966.11 KFM02024.1 - 3.8e-55 185.0 0.1 4.4e-55 184.8 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 KFM02024.1 - 1e-05 25.1 0.1 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin tRNA_m1G_MT PF01746.16 KFM02025.1 - 3.1e-32 111.6 0.5 4e-32 111.3 0.0 1.4 2 0 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase CoiA PF06054.6 KFM02025.1 - 0.0033 16.3 0.3 0.0041 16.0 0.2 1.2 1 0 0 1 1 1 1 Competence protein CoiA-like family PCNP PF15473.1 KFM02026.1 - 3.7e-71 238.3 13.3 4.1e-71 238.1 9.2 1.0 1 0 0 1 1 1 1 PEST, proteolytic signal-containing nuclear protein family DUF4602 PF15375.1 KFM02026.1 - 0.052 13.6 3.7 0.092 12.8 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4602) DUF566 PF04484.7 KFM02026.1 - 2.2 7.7 5.2 2.4 7.5 3.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) MRI PF15325.1 KFM02026.1 - 5.1 8.1 10.2 0.9 10.5 0.6 2.1 1 1 0 2 2 2 0 Modulator of retrovirus infection zf-H2C2_2 PF13465.1 KFM02027.1 - 5.1e-52 171.7 87.8 2e-08 34.1 0.2 13.9 14 1 0 14 14 14 10 Zinc-finger double domain zf-C2H2 PF00096.21 KFM02027.1 - 2.8e-40 134.2 95.1 0.00029 20.9 1.2 13.3 13 0 0 13 13 13 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM02027.1 - 4.3e-31 104.9 83.0 0.0027 17.9 0.4 13.2 13 0 0 13 13 13 11 C2H2-type zinc finger BTB PF00651.26 KFM02027.1 - 1.6e-22 79.5 1.9 1.6e-22 79.5 1.3 1.8 2 0 0 2 2 2 1 BTB/POZ domain zf-C2H2_jaz PF12171.3 KFM02027.1 - 5.8e-16 58.1 62.8 0.00089 19.3 0.4 12.4 11 1 1 12 12 11 8 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFM02027.1 - 1.3e-07 31.2 75.6 0.002 17.9 0.3 12.6 13 0 0 13 13 13 7 C2H2-type zinc finger zf-Di19 PF05605.7 KFM02027.1 - 8.1e-07 29.0 50.9 0.0016 18.4 0.5 8.4 5 3 2 7 7 7 4 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 KFM02027.1 - 2.6e-06 27.4 60.3 0.095 12.9 0.5 11.5 11 0 0 11 11 10 4 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KFM02027.1 - 5.5e-06 26.4 68.7 0.69 10.0 0.5 12.2 3 1 10 13 13 13 7 C2H2 type zinc-finger (2 copies) PhnA_Zn_Ribbon PF08274.7 KFM02027.1 - 0.0013 18.5 1.2 1.8 8.3 0.0 5.9 5 1 0 5 5 5 1 PhnA Zinc-Ribbon zf-H2C2 PF09337.5 KFM02027.1 - 0.002 17.4 2.1 0.002 17.4 1.5 3.1 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger DZR PF12773.2 KFM02027.1 - 0.049 13.4 38.0 1.6 8.6 1.7 7.8 5 2 1 6 6 6 0 Double zinc ribbon Ribosomal_L24e PF01246.15 KFM02028.1 - 1.5e-18 66.3 1.4 1.5e-18 66.3 1.0 2.0 2 1 0 2 2 2 1 Ribosomal protein L24e Red1 PF07964.6 KFM02028.1 - 0.48 8.5 7.7 0.56 8.2 5.4 1.0 1 0 0 1 1 1 0 Rec10 / Red1 Band_3_cyto PF07565.8 KFM02028.1 - 0.54 9.7 4.4 0.63 9.5 3.0 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain WTX PF09422.5 KFM02028.1 - 1.7 7.5 7.9 2 7.2 5.5 1.0 1 0 0 1 1 1 0 WTX protein DUF4658 PF15555.1 KFM02028.1 - 5.5 6.8 8.5 1.1 9.0 3.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4658) LRR_4 PF12799.2 KFM02029.1 - 3.3e-27 93.6 17.5 9.7e-07 28.2 1.0 4.6 4 0 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 KFM02029.1 - 6.3e-15 55.1 1.2 6.9e-12 45.2 0.0 2.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.1 KFM02029.1 - 1.4e-11 43.9 25.9 3.8e-07 29.7 4.5 3.6 1 1 1 3 3 3 3 Leucine rich repeat LRR_7 PF13504.1 KFM02029.1 - 1.9e-05 24.0 15.2 11 6.7 0.1 8.0 7 0 0 7 7 7 2 Leucine rich repeat IQ PF00612.22 KFM02029.1 - 0.00023 20.5 0.1 0.00051 19.4 0.0 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif LRR_1 PF00560.28 KFM02029.1 - 0.00063 19.4 18.3 0.24 11.5 0.1 7.0 8 0 0 8 8 8 2 Leucine Rich Repeat LRR_6 PF13516.1 KFM02029.1 - 0.0088 16.0 22.6 0.51 10.5 0.7 7.0 5 2 2 7 7 7 1 Leucine Rich repeat Neurexophilin PF06312.7 KFM02030.1 - 7.8e-51 172.4 0.0 1.2e-50 171.7 0.0 1.2 1 0 0 1 1 1 1 Neurexophilin Filamin PF00630.14 KFM02030.1 - 0.00011 22.6 0.0 0.00022 21.7 0.0 1.4 1 0 0 1 1 1 1 Filamin/ABP280 repeat PC-Esterase PF13839.1 KFM02030.1 - 0.00068 19.5 0.0 0.0015 18.3 0.0 1.7 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p CD20 PF04103.10 KFM02030.1 - 0.15 11.9 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 CD20-like family Ank PF00023.25 KFM02031.1 - 1.1e-31 106.9 3.4 2.3e-06 27.1 0.1 6.9 6 1 0 6 6 6 6 Ankyrin repeat Ank_2 PF12796.2 KFM02031.1 - 3.3e-28 97.8 9.9 7.1e-10 39.0 0.4 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFM02031.1 - 2.7e-23 81.8 5.2 2.3e-05 24.7 0.0 6.1 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM02031.1 - 1.9e-18 64.6 7.4 0.0029 17.6 0.0 7.4 6 1 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 KFM02031.1 - 5.8e-18 64.5 7.6 8.7e-09 35.3 0.2 5.3 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Glyco_transf_20 PF00982.16 KFM02031.1 - 0.065 11.7 0.8 0.099 11.0 0.6 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 20 Zona_pellucida PF00100.18 KFM02032.1 - 1.2e-34 119.9 2.7 1.6e-34 119.5 1.9 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain Ion_trans_2 PF07885.11 KFM02033.1 - 2.8e-32 110.2 19.4 7.3e-18 64.0 0.2 3.1 3 0 0 3 3 3 2 Ion channel DUF1104 PF06518.6 KFM02033.1 - 0.0043 17.1 0.5 0.0069 16.4 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1104) IclR PF01614.13 KFM02033.1 - 0.12 12.0 0.3 0.32 10.6 0.1 1.7 2 0 0 2 2 2 0 Bacterial transcriptional regulator RAMP4 PF06624.7 KFM02033.1 - 0.53 9.8 2.4 0.69 9.5 0.1 2.2 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 TALPID3 PF15324.1 KFM02035.1 - 0 1828.8 68.7 0 1519.8 29.0 2.1 1 1 1 2 2 2 2 Hedgehog signalling target DUF948 PF06103.6 KFM02035.1 - 3.1 7.7 9.9 1.8 8.5 0.0 3.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) zf-Tim10_DDP PF02953.10 KFM02036.1 - 1.1e-17 63.0 2.8 1.3e-17 62.7 2.0 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF2116 PF09889.4 KFM02036.1 - 0.017 14.9 1.0 0.025 14.3 0.7 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) PROCN PF08083.6 KFM02036.1 - 0.037 12.5 0.1 0.04 12.3 0.1 1.0 1 0 0 1 1 1 0 PROCN (NUC071) domain RBB1NT PF08169.6 KFM02037.1 - 4e-47 158.0 0.5 1.7e-46 156.1 0.4 2.2 1 0 0 1 1 1 1 RBB1NT (NUC162) domain ARID PF01388.16 KFM02037.1 - 7.2e-25 86.6 0.0 1.7e-24 85.4 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Tudor-knot PF11717.3 KFM02037.1 - 1.6e-14 53.3 2.2 5.7e-14 51.5 1.5 2.0 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain PWWP PF00855.12 KFM02037.1 - 1.7e-05 24.8 0.1 1.7e-05 24.8 0.0 4.4 5 0 0 5 5 5 1 PWWP domain Proteasome PF00227.21 KFM02038.1 - 1.1e-53 181.3 0.1 1.4e-53 181.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KFM02038.1 - 1e-14 53.5 0.1 1.7e-14 52.8 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Actin PF00022.14 KFM02039.1 - 3.2e-70 236.5 0.0 6.4e-69 232.2 0.0 2.0 1 1 0 1 1 1 1 Actin Nop14 PF04147.7 KFM02040.1 - 0.0026 15.7 6.5 0.0037 15.2 4.5 1.1 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.9 KFM02040.1 - 0.014 13.5 0.8 0.019 13.0 0.6 1.2 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.11 KFM02040.1 - 0.043 12.8 4.2 0.087 11.8 2.9 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Voldacs PF03517.8 KFM02040.1 - 0.06 13.1 7.0 0.048 13.4 3.4 1.9 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling Nucleoplasmin PF03066.10 KFM02040.1 - 0.075 12.5 13.4 0.074 12.5 7.3 2.3 2 0 0 2 2 2 0 Nucleoplasmin NOA36 PF06524.7 KFM02040.1 - 0.11 11.7 4.0 0.16 11.1 2.8 1.2 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.1 KFM02040.1 - 0.12 12.0 3.3 0.97 9.0 2.7 2.3 2 0 0 2 2 2 0 FAM176 family Plasmodium_Vir PF05795.6 KFM02040.1 - 0.25 10.5 0.3 0.77 8.8 0.1 1.8 1 1 0 1 1 1 0 Plasmodium vivax Vir protein RRN3 PF05327.6 KFM02040.1 - 0.32 9.0 4.4 0.46 8.5 3.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RNA_pol_3_Rpc31 PF11705.3 KFM02040.1 - 0.36 10.7 15.2 1 9.2 10.5 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CobT PF06213.7 KFM02040.1 - 1.7 7.6 15.0 2.5 7.1 8.5 2.4 3 0 0 3 3 3 0 Cobalamin biosynthesis protein CobT Paf1 PF03985.8 KFM02040.1 - 1.8 7.2 10.3 2.9 6.5 7.1 1.2 1 0 0 1 1 1 0 Paf1 HSP90 PF00183.13 KFM02040.1 - 6 5.1 11.2 9.1 4.5 7.8 1.1 1 0 0 1 1 1 0 Hsp90 protein EmrE PF13536.1 KFM02041.1 - 7.7e-10 38.9 0.7 7.7e-10 38.9 0.5 3.3 3 1 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KFM02041.1 - 1.5e-06 28.2 5.0 1.5e-06 28.2 3.5 4.2 3 1 1 4 4 4 1 EamA-like transporter family DUF914 PF06027.7 KFM02041.1 - 3.9e-06 25.9 9.3 6.2e-06 25.2 6.4 1.4 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) TPT PF03151.11 KFM02041.1 - 0.0083 15.7 2.2 0.0083 15.7 1.6 2.6 3 0 0 3 3 3 1 Triose-phosphate Transporter family DUF4619 PF15398.1 KFM02042.1 - 4.1e-75 252.9 3.0 4.7e-75 252.7 2.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4619) Acetyltransf_1 PF00583.19 KFM02043.1 - 1.6e-17 63.3 0.0 2.5e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFM02043.1 - 1.6e-10 40.9 0.1 3.4e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFM02043.1 - 4.2e-09 36.5 0.0 8.1e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFM02043.1 - 4.6e-09 35.9 0.0 8.8e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 KFM02043.1 - 6e-07 29.4 0.0 8.9e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KFM02043.1 - 7.7e-06 26.1 0.0 1.1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFM02043.1 - 0.00037 20.3 0.0 0.0006 19.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.2 KFM02043.1 - 0.028 13.2 0.1 0.04 12.7 0.1 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase Adap_comp_sub PF00928.16 KFM02044.1 - 3.3e-37 128.0 0.0 4.7e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Sec10 PF07393.6 KFM02045.1 - 3.3e-151 504.9 31.0 6.7e-114 381.5 10.0 3.5 2 1 1 3 3 3 2 Exocyst complex component Sec10 S-methyl_trans PF02574.11 KFM02045.1 - 0.041 13.1 0.2 0.079 12.2 0.1 1.4 1 0 0 1 1 1 0 Homocysteine S-methyltransferase Phage_GP20 PF06810.6 KFM02045.1 - 1.1 8.6 13.0 0.031 13.6 2.9 2.7 3 0 0 3 3 3 0 Phage minor structural protein GP20 Phasin PF05597.6 KFM02045.1 - 8.7 6.1 11.5 0.97 9.2 1.0 3.8 5 0 0 5 5 5 0 Poly(hydroxyalcanoate) granule associated protein (phasin) ACCA PF03255.9 KFM02045.1 - 8.9 5.8 9.9 0.33 10.5 1.1 2.7 3 0 0 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit TF_Otx PF03529.8 KFM02046.1 - 1.2e-37 127.9 14.5 1.2e-37 127.9 10.0 2.6 2 1 1 3 3 3 2 Otx1 transcription factor Homeobox PF00046.24 KFM02046.1 - 0.021 14.4 2.1 0.035 13.7 1.5 1.4 1 0 0 1 1 1 0 Homeobox domain DUF2723 PF11028.3 KFM02047.1 - 9.8e-33 113.1 6.3 9.8e-33 113.1 4.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2723) Pellino PF04710.9 KFM02048.1 - 6e-227 753.1 0.3 6.7e-227 752.9 0.2 1.0 1 0 0 1 1 1 1 Pellino zf-C3HC4_3 PF13920.1 KFM02048.1 - 3e-05 23.5 3.7 0.04 13.5 0.4 3.0 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM02048.1 - 0.0017 18.3 7.9 0.27 11.2 0.1 3.1 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFM02048.1 - 0.0033 17.0 1.9 0.28 10.9 0.2 3.1 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.1 KFM02048.1 - 0.19 11.5 14.7 1.5 8.6 2.2 3.1 2 1 0 2 2 2 0 Ring finger domain DUF2346 PF09803.4 KFM02049.1 - 0.0012 18.6 0.4 0.0012 18.6 0.3 7.9 9 3 1 10 10 10 1 Uncharacterized conserved protein (DUF2346) DUF972 PF06156.8 KFM02049.1 - 0.011 16.0 10.4 0.011 16.0 7.2 15.5 4 2 11 16 16 16 0 Protein of unknown function (DUF972) PIG-P PF08510.7 KFM02049.1 - 0.078 12.6 0.4 0.56 9.8 0.0 2.9 2 0 0 2 2 2 0 PIG-P TBP PF00352.16 KFM02050.1 - 1.2e-68 226.4 0.2 4.4e-34 115.6 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 KFM02050.1 - 4.1e-05 23.5 0.0 0.14 12.1 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Atg14 PF10186.4 KFM02051.1 - 2.1e-60 204.2 9.2 2.7e-60 203.8 6.4 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Exonuc_VII_L PF02601.10 KFM02051.1 - 0.98 8.5 7.4 1.4 8.0 5.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit F-box-like PF12937.2 KFM02052.1 - 0.00066 19.3 0.0 0.0016 18.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFM02052.1 - 0.0085 15.7 0.0 0.022 14.3 0.0 1.6 1 0 0 1 1 1 1 F-box domain Gal-bind_lectin PF00337.17 KFM02053.1 - 7.3e-37 125.6 0.0 9.2e-37 125.3 0.0 1.1 1 0 0 1 1 1 1 Galactoside-binding lectin SOCS PF12610.3 KFM02055.1 - 3.2e-19 69.0 3.6 3.2e-19 69.0 2.5 2.0 2 0 0 2 2 2 1 Suppressor of cytokine signalling SOCS_box PF07525.11 KFM02055.1 - 1e-12 47.6 0.1 2e-12 46.7 0.1 1.5 1 0 0 1 1 1 1 SOCS box SH2 PF00017.19 KFM02055.1 - 3.3e-08 33.2 0.0 9.1e-08 31.8 0.0 1.8 1 0 0 1 1 1 1 SH2 domain WD40 PF00400.27 KFM02056.1 - 2.7e-27 93.6 10.7 8.4e-10 38.1 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF3639 PF12341.3 KFM02056.1 - 3.6e-11 42.8 0.0 9e-11 41.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3639) HMG_box PF00505.14 KFM02056.1 - 1.8e-08 34.5 0.2 4.3e-08 33.3 0.1 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box eIF2A PF08662.6 KFM02056.1 - 9.1e-06 25.5 0.0 0.001 18.8 0.0 2.7 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A HMG_box_2 PF09011.5 KFM02056.1 - 0.01 16.1 1.5 0.032 14.6 1.0 1.9 1 0 0 1 1 1 0 HMG-box domain PXA PF02194.10 KFM02056.1 - 0.067 12.7 0.5 0.23 11.0 0.4 1.9 1 0 0 1 1 1 0 PXA domain GTP_cyclohydroI PF01227.17 KFM02057.1 - 1.9e-63 212.9 0.4 2.3e-63 212.7 0.3 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 KFM02057.1 - 0.00029 20.7 0.0 0.00052 19.8 0.0 1.5 1 1 0 1 1 1 1 QueF-like protein MAPKK1_Int PF08923.5 KFM02057.1 - 0.043 13.4 0.1 0.052 13.1 0.1 1.2 1 0 0 1 1 1 0 Mitogen-activated protein kinase kinase 1 interacting zf-C3HC4_3 PF13920.1 KFM02058.1 - 1.9e-11 43.4 10.7 4.6e-11 42.2 7.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM02058.1 - 0.013 15.5 14.2 0.013 15.5 9.9 2.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) CDKN3 PF05706.7 KFM02059.1 - 6.8e-72 240.3 1.8 8.1e-72 240.1 1.2 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.22 KFM02059.1 - 1.6e-08 34.1 0.0 2e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFM02059.1 - 9.2e-06 25.2 0.0 1.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 KFM02059.1 - 0.043 13.8 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 KFM02059.1 - 0.047 13.9 0.1 5.1 7.3 0.1 2.2 1 1 1 2 2 2 0 Tyrosine phosphatase family TGFb_propeptide PF00688.13 KFM02060.1 - 1.2e-73 247.3 4.2 2e-73 246.6 2.9 1.3 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.15 KFM02060.1 - 5.3e-41 139.1 0.8 9.2e-41 138.3 0.6 1.4 1 0 0 1 1 1 1 Transforming growth factor beta like domain DDHD PF02862.12 KFM02062.1 - 2.5e-57 194.3 0.0 6.5e-57 192.9 0.0 1.7 1 1 0 1 1 1 1 DDHD domain DUF676 PF05057.9 KFM02062.1 - 0.054 12.7 0.0 2.8 7.1 0.0 2.4 2 0 0 2 2 2 0 Putative serine esterase (DUF676) FERM_M PF00373.13 KFM02063.1 - 6.7e-48 162.0 0.9 1.1e-47 161.3 0.1 1.8 2 0 0 2 2 2 1 FERM central domain FERM_N PF09379.5 KFM02063.1 - 1.9e-07 31.0 0.1 1.4e-06 28.2 0.1 2.4 1 1 0 1 1 1 1 FERM N-terminal domain PH PF00169.24 KFM02063.1 - 7.4e-06 26.1 0.1 2.3e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 PH domain Tenui_NCP PF04876.7 KFM02063.1 - 0.02 14.4 0.0 0.044 13.3 0.0 1.5 1 0 0 1 1 1 0 Tenuivirus major non-capsid protein Acetyltransf_1 PF00583.19 KFM02064.1 - 1.3e-10 41.1 0.0 2e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFM02064.1 - 9.2e-10 38.5 0.0 1.3e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KFM02064.1 - 0.0003 20.7 0.0 0.00036 20.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFM02064.1 - 0.0063 16.6 0.0 0.0082 16.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFM02064.1 - 0.01 15.7 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PPR_3 PF13812.1 KFM02064.1 - 0.12 12.7 0.0 6.8 7.2 0.0 2.9 2 1 1 3 3 3 0 Pentatricopeptide repeat domain DSPc PF00782.15 KFM02065.1 - 2.2e-38 130.8 0.0 2.8e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFM02065.1 - 0.0088 15.4 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase HTH_33 PF13592.1 KFM02065.1 - 0.12 11.9 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix AAA PF00004.24 KFM02066.1 - 4.6e-44 149.8 0.0 8.3e-44 148.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFM02066.1 - 1.3e-07 31.8 0.1 0.00038 20.5 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 KFM02066.1 - 2.6e-07 30.8 0.2 4.6e-06 26.7 0.0 2.4 2 1 1 3 3 2 1 AAA ATPase domain AAA_2 PF07724.9 KFM02066.1 - 5e-06 26.5 0.0 5.9e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KFM02066.1 - 7.2e-06 25.7 0.2 0.0002 21.1 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KFM02066.1 - 1.6e-05 24.1 0.0 3.5e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KFM02066.1 - 6.7e-05 23.7 0.0 0.00019 22.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFM02066.1 - 0.001 18.7 0.0 0.0023 17.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 KFM02066.1 - 0.0011 18.8 0.0 0.003 17.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KFM02066.1 - 0.0013 18.5 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 KFM02066.1 - 0.0026 16.7 0.0 0.0091 14.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 KFM02066.1 - 0.003 16.9 0.0 0.0065 15.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 KFM02066.1 - 0.0032 16.9 0.1 0.017 14.5 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 KFM02066.1 - 0.0032 17.7 0.0 0.01 16.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KFM02066.1 - 0.0052 16.3 0.0 0.017 14.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KFM02066.1 - 0.0069 16.5 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 KFM02066.1 - 0.0087 14.8 0.0 0.015 14.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 KFM02066.1 - 0.0093 15.1 0.0 0.019 14.1 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Thymidylate_kin PF02223.12 KFM02066.1 - 0.017 14.5 0.1 0.81 9.0 0.0 2.4 2 1 0 2 2 2 0 Thymidylate kinase NACHT PF05729.7 KFM02066.1 - 0.023 14.3 0.0 0.12 11.9 0.0 2.0 1 1 1 2 2 2 0 NACHT domain AAA_28 PF13521.1 KFM02066.1 - 0.026 14.4 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KFM02066.1 - 0.043 13.3 0.1 0.096 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KFM02066.1 - 0.046 12.8 0.5 0.44 9.6 0.0 2.5 2 1 1 3 3 3 0 KaiC SKI PF01202.17 KFM02066.1 - 0.051 13.4 0.0 0.35 10.7 0.0 2.1 2 0 0 2 2 2 0 Shikimate kinase Med3 PF11593.3 KFM02066.1 - 0.057 12.6 0.1 0.077 12.2 0.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Arch_ATPase PF01637.13 KFM02066.1 - 0.072 12.7 0.0 0.34 10.5 0.0 2.1 1 1 0 1 1 1 0 Archaeal ATPase PhoH PF02562.11 KFM02066.1 - 0.077 12.2 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.1 KFM02066.1 - 0.078 12.5 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 KFM02066.1 - 0.14 11.0 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ERO1 PF04137.10 KFM02067.1 - 3.4e-127 424.3 0.0 3.8e-127 424.1 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DUF1084 PF06454.6 KFM02068.1 - 0.0012 17.8 4.6 0.0025 16.8 1.5 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1084) Thioredoxin_6 PF13848.1 KFM02069.1 - 1.9e-24 86.5 0.0 4.4e-19 68.9 0.0 3.8 3 1 1 4 4 4 2 Thioredoxin-like domain Thioredoxin PF00085.15 KFM02069.1 - 1.4e-11 44.0 0.0 7.6e-11 41.6 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin Dimer_Tnp_hAT PF05699.9 KFM02070.1 - 0.093 12.3 0.4 0.21 11.2 0.3 1.6 1 1 0 1 1 1 0 hAT family C-terminal dimerisation region RLL PF10036.4 KFM02072.1 - 1.9e-95 318.9 2.1 2.2e-95 318.8 1.5 1.0 1 0 0 1 1 1 1 Putative carnitine deficiency-associated protein Cactin_mid PF10312.4 KFM02072.1 - 0.041 13.1 0.2 0.054 12.7 0.1 1.2 1 0 0 1 1 1 0 Conserved mid region of cactin G-gamma PF00631.17 KFM02073.1 - 9.3e-21 73.3 0.0 1e-20 73.2 0.0 1.0 1 0 0 1 1 1 1 GGL domain FERM_C PF09380.5 KFM02074.1 - 4.5e-15 55.6 0.0 1.1e-14 54.3 0.0 1.7 1 1 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.13 KFM02074.1 - 6.7e-15 55.3 0.6 2.4e-14 53.6 0.4 1.9 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.5 KFM02074.1 - 1.5e-14 53.7 0.1 4.1e-14 52.3 0.0 1.8 1 0 0 1 1 1 1 FERM N-terminal domain Vac7 PF12751.2 KFM02074.1 - 0.14 11.0 4.6 0.24 10.1 3.2 1.3 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 DUF2422 PF10337.4 KFM02075.1 - 0.18 10.5 0.9 0.23 10.2 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) SPRY PF00622.23 KFM02077.1 - 5.6e-11 42.6 0.0 1.1e-08 35.2 0.0 2.6 1 1 0 1 1 1 1 SPRY domain fn3 PF00041.16 KFM02077.1 - 7.6e-10 38.7 0.0 1.5e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain PRY PF13765.1 KFM02077.1 - 0.00098 18.6 0.1 0.0027 17.1 0.0 1.8 1 1 1 2 2 2 1 SPRY-associated domain ATP-synt_E_2 PF08112.6 KFM02077.1 - 0.14 12.2 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 ATP synthase epsilon subunit BLOC1_2 PF10046.4 KFM02077.1 - 0.32 11.1 2.1 14 5.9 0.1 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4200 PF13863.1 KFM02077.1 - 0.33 10.9 3.1 0.47 10.4 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Nup54 PF13874.1 KFM02077.1 - 0.51 9.9 3.9 0.93 9.1 2.7 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Phosphorylase PF00343.15 KFM02078.1 - 0 1189.1 0.2 0 1188.9 0.1 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Abhydrolase_6 PF12697.2 KFM02079.1 - 1.6e-18 67.4 1.5 3.6e-18 66.2 1.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFM02079.1 - 3.4e-18 65.8 0.1 6.8e-18 64.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFM02079.1 - 1.6e-09 37.6 0.0 9e-08 31.9 0.0 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KFM02079.1 - 2.7e-06 27.1 0.0 3.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KFM02079.1 - 0.00079 18.9 0.1 0.88 8.9 0.0 3.0 2 1 0 3 3 3 1 Phospholipase/Carboxylesterase Thioesterase PF00975.15 KFM02079.1 - 0.0012 19.0 0.0 0.0022 18.2 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S9 PF00326.16 KFM02079.1 - 0.0043 16.3 0.0 0.011 14.9 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 KFM02079.1 - 0.0062 16.3 0.1 0.015 15.1 0.1 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Lipase_3 PF01764.20 KFM02079.1 - 0.03 13.9 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Cutinase PF01083.17 KFM02079.1 - 0.069 12.8 0.0 0.097 12.4 0.0 1.1 1 0 0 1 1 1 0 Cutinase PAC2 PF09754.4 KFM02079.1 - 0.087 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 PAC2 family Peptidase_M57 PF12388.3 KFM02079.1 - 0.16 11.2 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase DUF4482 PF14818.1 KFM02080.1 - 0.01 16.5 4.5 0.01 16.5 3.1 8.6 2 2 6 8 8 8 0 Domain of unknown function (DUF4482) Baculo_PEP_C PF04513.7 KFM02080.1 - 0.26 11.1 0.0 0.26 11.1 0.0 7.2 4 3 3 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus FAD-SLDH PF12318.3 KFM02080.1 - 9.5 5.8 16.0 0.32 10.6 2.2 3.7 3 1 1 4 4 4 0 Membrane bound FAD containing D-sorbitol dehydrogenase GAS PF13851.1 KFM02081.1 - 0.011 14.9 14.2 0.24 10.5 2.9 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Tropomyosin PF00261.15 KFM02081.1 - 0.018 14.1 10.6 0.029 13.4 7.4 1.3 1 0 0 1 1 1 0 Tropomyosin UPF0240 PF06784.6 KFM02081.1 - 0.025 14.2 4.8 0.031 13.9 3.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) DUF4351 PF14261.1 KFM02081.1 - 0.069 13.0 0.3 0.15 11.9 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4351) GCR PF02155.10 KFM02081.1 - 0.094 11.4 0.4 0.1 11.3 0.3 1.1 1 0 0 1 1 1 0 Glucocorticoid receptor Fmp27_WPPW PF10359.4 KFM02081.1 - 0.13 10.6 5.4 0.15 10.3 3.8 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Tautomerase PF01361.16 KFM02081.1 - 0.19 11.3 1.0 1.4 8.5 0.1 2.4 2 1 1 3 3 3 0 Tautomerase enzyme KIAA1430 PF13879.1 KFM02081.1 - 0.36 11.2 6.2 0.63 10.4 4.1 1.6 1 1 0 1 1 1 0 KIAA1430 homologue MerR-DNA-bind PF09278.6 KFM02081.1 - 0.5 10.7 6.1 4 7.8 0.4 2.3 2 0 0 2 2 2 0 MerR, DNA binding APG6 PF04111.7 KFM02081.1 - 0.84 8.6 10.9 0.92 8.4 7.6 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Baculo_PEP_C PF04513.7 KFM02081.1 - 0.85 9.4 5.8 6.1 6.6 3.7 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus LMBR1 PF04791.11 KFM02081.1 - 1.2 7.6 3.5 1.3 7.5 2.4 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2992 PF11208.3 KFM02081.1 - 1.7 8.5 6.9 1.8 8.4 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) DUF972 PF06156.8 KFM02081.1 - 3.1 8.2 9.9 5.9 7.2 6.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) IncA PF04156.9 KFM02081.1 - 4.6 6.7 9.3 5.3 6.5 6.4 1.1 1 0 0 1 1 1 0 IncA protein Tup_N PF08581.5 KFM02081.1 - 7.4 6.8 11.4 0.61 10.3 2.5 2.2 1 1 1 2 2 2 0 Tup N-terminal XhlA PF10779.4 KFM02081.1 - 9.3 6.2 12.8 8.6e+02 -0.1 8.8 2.2 1 1 0 1 1 1 0 Haemolysin XhlA WW PF00397.21 KFM02082.1 - 2e-09 37.1 15.3 2.6e-09 36.7 3.4 3.5 3 0 0 3 3 3 2 WW domain Suppressor_APC PF11414.3 KFM02082.1 - 1.1 9.0 7.3 0.5 10.1 2.6 2.1 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein GBP PF02263.14 KFM02083.1 - 3.6e-99 331.0 0.1 4.8e-99 330.6 0.1 1.1 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.9 KFM02083.1 - 2.8e-06 26.7 0.1 4.5e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain Tic20 PF09685.5 KFM02083.1 - 0.018 15.0 1.0 0.042 13.8 0.7 1.5 1 0 0 1 1 1 0 Tic20-like protein DUF1977 PF09320.6 KFM02083.1 - 0.11 12.7 0.7 0.28 11.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1977) CNH PF00780.17 KFM02084.1 - 1.8e-78 263.7 0.9 3.3e-78 262.8 0.6 1.4 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.20 KFM02084.1 - 1.2e-64 217.9 0.0 1.8e-64 217.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM02084.1 - 2.9e-39 134.7 0.0 4.7e-39 134.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM02084.1 - 0.0012 17.9 0.0 0.0022 16.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 KFM02085.1 - 2.8e-62 210.2 0.0 3.5e-62 209.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM02085.1 - 3.1e-27 95.2 0.1 2e-26 92.6 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFM02085.1 - 0.031 14.0 0.1 0.23 11.1 0.0 2.2 2 2 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KFM02085.1 - 0.08 11.7 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.1 KFM02085.1 - 0.094 11.6 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like LRR_8 PF13855.1 KFM02086.1 - 0.045 13.5 3.8 0.38 10.5 0.1 2.6 2 1 1 3 3 3 0 Leucine rich repeat LRR_4 PF12799.2 KFM02086.1 - 0.73 9.5 4.2 3 7.5 2.1 2.4 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KFM02086.1 - 4.3 7.7 4.8 39 4.7 0.0 3.7 4 0 0 4 4 4 0 Leucine Rich repeat DAO PF01266.19 KFM02087.1 - 8.6e-58 195.9 0.0 9.9e-58 195.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KFM02087.1 - 0.0005 20.1 0.0 0.13 12.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFM02087.1 - 0.0007 19.5 0.3 0.0024 17.8 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KFM02087.1 - 0.0074 15.3 0.1 0.16 10.9 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 KFM02087.1 - 0.014 14.3 0.1 0.029 13.2 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KFM02087.1 - 0.014 15.3 0.3 0.15 11.9 0.2 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFM02087.1 - 0.014 14.4 0.1 0.026 13.6 0.0 1.5 1 1 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 KFM02087.1 - 0.14 10.9 0.2 0.25 10.1 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain RasGEF PF00617.14 KFM02088.1 - 7.4e-51 172.5 0.7 1.5e-50 171.5 0.5 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KFM02088.1 - 1.7e-31 108.4 1.5 1.2e-30 105.6 0.0 2.9 3 0 0 3 3 3 1 RasGEF N-terminal motif RhoGEF PF00621.15 KFM02088.1 - 4.7e-19 68.9 2.1 1.6e-18 67.2 1.4 2.0 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 KFM02088.1 - 1.8e-11 44.1 0.1 1.1e-10 41.6 0.0 2.3 2 0 0 2 2 2 1 PH domain Histone PF00125.19 KFM02088.1 - 2.6e-06 27.4 0.0 1.2e-05 25.3 0.0 2.2 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 PH_10 PF15411.1 KFM02088.1 - 0.0092 16.1 0.2 0.029 14.5 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.1 KFM02088.1 - 0.05 13.7 0.0 0.21 11.7 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain Methyltransf_16 PF10294.4 KFM02089.1 - 7.1e-31 106.9 0.0 8.4e-31 106.7 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 KFM02089.1 - 0.068 12.8 0.0 0.069 12.8 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain FbpA PF05833.6 KFM02090.1 - 1e-37 129.7 17.1 2.7e-37 128.3 11.8 1.7 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF3441 PF11923.3 KFM02090.1 - 2.6e-32 110.7 0.1 2.6e-32 110.7 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3441) DUF814 PF05670.8 KFM02090.1 - 1.4e-24 85.7 0.0 4.3e-24 84.2 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Kelch_4 PF13418.1 KFM02091.1 - 3.5e-32 109.9 23.1 4.8e-10 39.0 0.1 7.8 6 1 1 7 7 7 6 Galactose oxidase, central domain Kelch_3 PF13415.1 KFM02091.1 - 3.6e-31 106.5 14.8 9.2e-08 32.0 0.2 8.0 7 1 0 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.1 KFM02091.1 - 7.4e-24 83.2 15.5 3.5e-05 23.6 0.0 7.4 7 2 0 7 7 7 6 Kelch motif Kelch_6 PF13964.1 KFM02091.1 - 1.5e-22 78.7 15.7 4.3e-07 29.8 0.1 7.0 6 1 1 7 7 7 3 Kelch motif Kelch_1 PF01344.20 KFM02091.1 - 2.9e-18 65.1 15.8 0.00021 20.7 0.1 6.5 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 KFM02091.1 - 2.1e-14 52.6 19.5 0.00016 21.3 0.0 6.9 6 1 0 6 6 6 5 Kelch motif Rax2 PF12768.2 KFM02091.1 - 0.012 14.7 0.1 0.04 13.1 0.0 1.8 2 0 0 2 2 2 0 Cortical protein marker for cell polarity Kelch_4 PF13418.1 KFM02092.1 - 3.4e-32 109.9 20.1 3.1e-09 36.4 0.4 7.1 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_3 PF13415.1 KFM02092.1 - 3.7e-32 109.7 18.4 3e-07 30.4 0.1 6.8 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_6 PF13964.1 KFM02092.1 - 1.3e-26 91.5 19.1 3.7e-07 30.0 0.1 6.7 4 1 2 6 6 6 5 Kelch motif Kelch_5 PF13854.1 KFM02092.1 - 1.6e-18 66.2 5.5 0.0007 19.4 0.1 5.9 7 0 0 7 7 7 4 Kelch motif Kelch_1 PF01344.20 KFM02092.1 - 1.6e-18 65.9 10.0 4.3e-05 22.9 0.3 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.10 KFM02092.1 - 3.4e-17 61.4 18.8 2.3e-06 27.1 0.0 6.1 5 2 1 6 6 6 5 Kelch motif PQQ_3 PF13570.1 KFM02092.1 - 0.02 15.1 0.7 35 4.8 0.0 4.2 4 1 0 4 4 4 0 PQQ-like domain DNA_pol_E_B PF04042.11 KFM02093.1 - 1.2e-51 174.9 0.8 1.9e-51 174.2 0.5 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Dpoe2NT PF12213.3 KFM02093.1 - 2.2e-19 69.1 2.1 4.5e-19 68.1 1.5 1.6 1 0 0 1 1 1 1 DNA polymerases epsilon N terminal MGAT2 PF05060.9 KFM02095.1 - 2.6e-140 467.3 0.1 2.9e-140 467.2 0.1 1.0 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) LRR_4 PF12799.2 KFM02096.1 - 2.4e-20 71.6 13.2 5.3e-10 38.6 0.8 4.7 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM02096.1 - 1.8e-13 49.9 18.5 9.7e-09 34.8 2.6 3.2 2 1 0 3 3 3 3 Leucine rich repeat LRR_7 PF13504.1 KFM02096.1 - 3.5e-13 47.4 13.8 0.014 15.5 0.1 7.8 7 0 0 7 7 7 4 Leucine rich repeat LRR_1 PF00560.28 KFM02096.1 - 6.2e-12 43.8 19.7 0.018 14.9 0.0 7.6 7 0 0 7 7 7 5 Leucine Rich Repeat LRR_6 PF13516.1 KFM02096.1 - 2.3e-06 27.0 12.7 0.77 10.0 0.0 6.3 4 1 2 6 6 6 3 Leucine Rich repeat SapA PF02199.10 KFM02096.1 - 0.093 12.5 1.8 0.21 11.3 1.2 1.6 1 0 0 1 1 1 0 Saposin A-type domain SANTA PF09133.5 KFM02098.1 - 1.2e-14 53.9 0.3 1.3e-14 53.8 0.2 1.0 1 0 0 1 1 1 1 SANTA (SANT Associated) PDDEXK_4 PF14281.1 KFM02099.1 - 0.0077 16.1 0.0 0.0086 15.9 0.0 1.1 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Helicase_C PF00271.26 KFM02100.1 - 5.8e-18 64.5 0.6 2.4e-17 62.5 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC4 PF02732.10 KFM02100.1 - 1.1e-10 41.4 0.3 4e-10 39.6 0.2 2.1 1 0 0 1 1 1 1 ERCC4 domain DEAD PF00270.24 KFM02100.1 - 7.7e-06 25.5 0.0 1.8e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KFM02100.1 - 0.00097 19.0 4.7 0.0017 18.2 0.0 3.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SOUL PF04832.7 KFM02101.1 - 1.8e-41 141.6 0.0 2e-41 141.4 0.0 1.0 1 0 0 1 1 1 1 SOUL heme-binding protein FKBP_C PF00254.23 KFM02102.1 - 9.3e-14 51.2 0.5 7.8e-13 48.2 0.3 2.1 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF3934 PF13070.1 KFM02102.1 - 4.6 7.5 7.4 1.9 8.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3934) TPR_14 PF13428.1 KFM02103.1 - 2.3e-12 46.3 0.0 3.1 8.6 0.0 7.1 6 1 2 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 KFM02103.1 - 1.8e-09 37.9 0.3 0.031 14.9 0.0 4.1 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFM02103.1 - 5.4e-06 26.6 0.0 0.14 12.5 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFM02103.1 - 0.00015 21.6 1.5 0.059 13.3 0.2 4.1 2 1 1 3 3 3 2 Tetratricopeptide repeat Suf PF05843.9 KFM02103.1 - 0.00016 21.4 6.1 0.0042 16.8 0.0 3.6 3 2 1 5 5 5 1 Suppressor of forked protein (Suf) TPR_11 PF13414.1 KFM02103.1 - 0.00041 19.9 2.1 0.03 13.9 0.1 3.8 2 1 3 5 5 5 1 TPR repeat TPR_2 PF07719.12 KFM02103.1 - 0.0012 18.5 5.3 3.1 7.9 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFM02103.1 - 0.0096 16.3 0.7 58 4.4 0.0 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat Ribophorin_II PF05817.9 KFM02103.1 - 0.1 10.7 0.1 0.14 10.3 0.0 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II NEP PF10167.4 KFM02103.1 - 0.13 11.9 1.7 0.83 9.3 0.1 2.7 2 1 0 2 2 2 0 Uncharacterised conserved protein Syntaxin-6_N PF09177.6 KFM02103.1 - 2 8.9 5.8 2.7 8.4 0.1 3.9 4 1 1 5 5 4 0 Syntaxin 6, N-terminal CLASP_N PF12348.3 KFM02104.1 - 9.7e-12 44.7 2.6 0.0004 19.8 0.1 3.4 3 0 0 3 3 3 3 CLASP N terminal NUC173 PF08161.7 KFM02104.1 - 0.00032 20.1 0.7 0.18 11.1 0.1 2.9 2 0 0 2 2 2 2 NUC173 domain HEAT PF02985.17 KFM02104.1 - 0.00037 20.3 4.8 4.2 7.7 0.0 5.8 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 KFM02104.1 - 0.0027 17.9 1.5 2.4 8.5 0.2 4.2 3 1 0 3 3 3 1 HEAT repeats ParcG PF10274.4 KFM02104.1 - 0.044 13.6 0.6 0.69 9.7 0.2 2.6 2 1 0 2 2 2 0 Parkin co-regulated protein DUF445 PF04286.7 KFM02104.1 - 0.4 10.1 0.0 0.4 10.1 0.0 3.7 5 0 0 5 5 5 0 Protein of unknown function (DUF445) LRR_8 PF13855.1 KFM02105.1 - 2.7e-40 135.9 32.1 5.6e-14 51.6 7.3 3.9 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.2 KFM02105.1 - 1.9e-19 68.8 14.6 1.9e-05 24.1 3.9 4.6 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM02105.1 - 7.5e-16 55.7 15.5 0.01 15.7 0.0 7.9 8 0 0 8 8 7 5 Leucine Rich Repeat I-set PF07679.11 KFM02105.1 - 1.5e-15 56.8 0.0 3.1e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_5 PF13306.1 KFM02105.1 - 5.5e-15 55.2 0.0 1.4e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) Ig_2 PF13895.1 KFM02105.1 - 6.7e-08 32.5 0.0 1.6e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFM02105.1 - 2.3e-07 31.2 0.0 5.9e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFM02105.1 - 5.3e-06 26.4 0.0 1.2e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain LRR_9 PF14580.1 KFM02105.1 - 7.2e-06 25.6 2.1 0.0014 18.2 0.7 2.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_7 PF13504.1 KFM02105.1 - 0.0001 21.8 23.9 0.41 11.0 0.0 7.6 8 0 0 8 8 6 2 Leucine rich repeat fn3 PF00041.16 KFM02105.1 - 0.00017 21.6 0.1 0.00049 20.1 0.0 1.8 2 0 0 2 2 1 1 Fibronectin type III domain V-set PF07686.12 KFM02105.1 - 0.0054 16.6 0.1 0.032 14.1 0.0 2.2 2 1 0 2 2 2 1 Immunoglobulin V-set domain LRR_6 PF13516.1 KFM02105.1 - 0.0086 16.0 21.4 3.1 8.1 0.0 6.7 8 0 0 8 8 7 2 Leucine Rich repeat C2-set_2 PF08205.7 KFM02105.1 - 0.02 14.7 0.0 0.054 13.4 0.0 1.8 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain DUF240 PF03086.9 KFM02105.1 - 0.15 11.7 4.9 0.19 11.3 2.6 1.7 1 1 1 2 2 2 0 MG032/MG096/MG288 family 2 P12 PF12669.2 KFM02105.1 - 0.81 9.9 3.4 2.3 8.5 2.3 1.7 1 0 0 1 1 1 0 Virus attachment protein p12 family LSR PF05624.9 KFM02105.1 - 1.1 9.0 11.9 0.056 13.1 1.6 2.5 2 0 0 2 2 2 0 Lipolysis stimulated receptor (LSR) Homeobox PF00046.24 KFM02107.1 - 6e-24 83.4 4.3 9.6e-24 82.7 3.0 1.3 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFM02107.1 - 0.0055 16.3 0.1 0.013 15.1 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain HA PF03457.9 KFM02107.1 - 0.24 11.5 6.1 0.16 12.0 0.9 2.2 1 1 1 2 2 2 0 Helicase associated domain DUF4171 PF13775.1 KFM02108.1 - 1.2e-42 145.1 22.8 1.2e-42 145.1 15.8 4.2 5 0 0 5 5 5 1 Domain of unknown function (DUF4171) HMG_box PF00505.14 KFM02108.1 - 5.1e-15 55.4 2.4 5.1e-15 55.4 1.7 3.7 4 0 0 4 4 4 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFM02108.1 - 7.5e-09 35.8 3.4 7.5e-09 35.8 2.4 2.8 2 1 1 3 3 3 1 HMG-box domain p53-inducible11 PF14936.1 KFM02108.1 - 0.035 14.0 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 Tumour protein p53-inducible protein 11 VHS PF00790.14 KFM02109.1 - 2e-45 153.8 0.0 3.6e-45 153.0 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 KFM02109.1 - 9.7e-33 112.1 1.2 2e-32 111.1 0.8 1.5 1 0 0 1 1 1 1 GAT domain Heme_oxygenase PF01126.15 KFM02110.1 - 2.5e-83 278.6 3.3 3.2e-83 278.3 2.3 1.1 1 0 0 1 1 1 1 Heme oxygenase Ras PF00071.17 KFM02111.1 - 4.3e-40 136.7 0.0 6.7e-40 136.1 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM02111.1 - 5.1e-16 59.2 0.0 1.2e-15 58.0 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM02111.1 - 4.3e-08 32.5 0.0 6e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFM02111.1 - 8.3e-05 22.1 0.0 0.00023 20.6 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFM02111.1 - 0.00065 19.6 0.0 0.0013 18.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFM02111.1 - 0.0043 16.2 0.1 0.0058 15.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arch_ATPase PF01637.13 KFM02111.1 - 0.016 14.9 0.1 0.037 13.7 0.1 1.7 1 1 0 1 1 1 0 Archaeal ATPase SRPRB PF09439.5 KFM02111.1 - 0.02 14.0 0.0 0.069 12.3 0.0 1.8 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 KFM02111.1 - 0.064 13.4 0.0 3.9 7.6 0.0 2.7 3 1 1 4 4 4 0 AAA domain AAA_14 PF13173.1 KFM02111.1 - 0.066 13.1 0.2 0.41 10.5 0.1 2.3 1 1 0 1 1 1 0 AAA domain AICARFT_IMPCHas PF01808.13 KFM02111.1 - 0.12 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 AICARFT/IMPCHase bienzyme Globin PF00042.17 KFM02112.1 - 1.1e-21 77.2 0.6 1.4e-21 76.8 0.1 1.4 2 0 0 2 2 2 1 Globin Fox-1_C PF12414.3 KFM02113.1 - 2.2e-23 82.4 4.8 8.9e-23 80.5 1.8 2.5 2 0 0 2 2 2 1 Calcitonin gene-related peptide regulator C terminal RRM_1 PF00076.17 KFM02113.1 - 7.2e-19 67.1 0.1 1.1e-18 66.5 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM02113.1 - 1.7e-15 56.7 0.1 2.8e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM02113.1 - 5.7e-11 42.0 0.1 1.2e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ECM1 PF05782.6 KFM02113.1 - 0.016 13.9 0.5 0.024 13.3 0.3 1.2 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) RRM_3 PF08777.6 KFM02113.1 - 0.069 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif Thioredoxin PF00085.15 KFM02115.1 - 5.2e-29 99.9 0.1 6.9e-29 99.5 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KFM02115.1 - 6.1e-09 36.0 0.0 3.8e-08 33.5 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KFM02115.1 - 1.1e-06 28.5 0.1 1.6e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.1 KFM02115.1 - 4.4e-05 23.5 0.0 0.0025 17.8 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_3 PF13192.1 KFM02115.1 - 0.00019 21.1 0.1 0.00027 20.6 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin domain AhpC-TSA PF00578.16 KFM02115.1 - 0.0025 17.5 0.0 0.0032 17.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family DSBA PF01323.15 KFM02115.1 - 0.011 15.3 0.0 0.27 10.7 0.0 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_9 PF14595.1 KFM02115.1 - 0.017 14.7 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin DUF836 PF05768.9 KFM02115.1 - 0.046 13.9 0.0 0.068 13.4 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Redoxin PF08534.5 KFM02115.1 - 0.073 12.6 0.9 0.37 10.3 0.1 2.0 1 1 1 2 2 2 0 Redoxin Pyr_redox_3 PF13738.1 KFM02116.1 - 2.8e-38 132.0 0.0 4.4e-38 131.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFM02116.1 - 2e-07 30.9 0.0 5.8e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KFM02116.1 - 2.4e-07 30.0 0.0 4.4e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KFM02116.1 - 6.1e-07 29.5 0.0 2.3e-06 27.6 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KFM02116.1 - 2.4e-06 26.7 0.0 0.00017 20.5 0.0 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KFM02116.1 - 1.3e-05 23.8 0.0 0.004 15.6 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein FMO-like PF00743.14 KFM02116.1 - 3.3e-05 22.3 0.0 0.0001 20.7 0.0 1.8 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Thi4 PF01946.12 KFM02116.1 - 4.4e-05 22.6 0.0 8.5e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 KFM02116.1 - 0.00053 20.3 0.0 0.049 14.0 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFM02116.1 - 0.0009 19.0 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KFM02116.1 - 0.0011 18.1 0.0 0.0017 17.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 KFM02116.1 - 0.0019 17.1 0.0 0.0056 15.5 0.0 1.6 1 1 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.19 KFM02116.1 - 0.029 13.4 0.0 0.19 10.7 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase GIDA PF01134.17 KFM02116.1 - 0.047 12.5 0.0 0.43 9.3 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A LigT_PEase PF02834.11 KFM02116.1 - 0.056 13.4 0.0 9.2 6.3 0.0 2.5 2 0 0 2 2 2 0 LigT like Phosphoesterase Peptidase_C71 PF12386.3 KFM02116.1 - 0.13 11.6 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 Pseudomurein endo-isopeptidase Pei NAD_binding_7 PF13241.1 KFM02116.1 - 0.19 11.9 0.0 9.8 6.5 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding eIF-3_zeta PF05091.7 KFM02117.1 - 1.5e-212 706.7 3.9 1.8e-212 706.5 2.7 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PMP22_Claudin PF00822.15 KFM02118.1 - 8e-58 194.7 1.8 1.1e-57 194.3 1.2 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFM02118.1 - 2.3e-21 76.2 0.9 3.9e-21 75.4 0.6 1.4 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Tetraspannin PF00335.15 KFM02118.1 - 0.0048 16.1 0.0 0.008 15.4 0.0 1.5 1 0 0 1 1 1 1 Tetraspanin family Ras PF00071.17 KFM02119.1 - 4.3e-36 123.7 0.0 4.9e-36 123.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM02119.1 - 1.4e-15 57.7 0.0 2.2e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KFM02119.1 - 4.8e-05 22.8 0.0 5.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 KFM02119.1 - 0.00011 21.5 0.0 0.00012 21.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFM02119.1 - 0.00016 21.6 0.0 0.00028 20.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_1 PF00036.27 KFM02120.1 - 7.3e-14 49.9 2.8 2e-06 26.6 0.5 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KFM02120.1 - 2.5e-12 45.5 1.8 5.1e-07 29.0 0.2 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 KFM02120.1 - 1e-11 43.6 1.3 0.0001 21.4 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 KFM02120.1 - 3.1e-11 42.6 1.5 2.8e-07 30.0 0.2 2.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.1 KFM02120.1 - 8.4e-11 41.8 0.5 1.2e-10 41.3 0.3 1.5 1 1 0 1 1 1 1 EF-hand domain pair EFhand_Ca_insen PF08726.5 KFM02120.1 - 0.093 12.7 0.8 0.26 11.2 0.0 2.0 2 1 1 3 3 3 0 Ca2+ insensitive EF hand PX PF00787.19 KFM02121.1 - 6.2e-18 64.6 0.0 1.1e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 PX domain PB1 PF00564.19 KFM02121.1 - 2.1e-16 59.3 1.6 5.6e-16 57.9 0.6 2.0 2 0 0 2 2 2 1 PB1 domain SH3_1 PF00018.23 KFM02121.1 - 7.2e-12 44.5 0.1 1.6e-11 43.3 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KFM02121.1 - 6.6e-11 41.6 0.0 1.4e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFM02121.1 - 7.7e-09 34.9 0.0 4.5e-08 32.4 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain fn3 PF00041.16 KFM02123.1 - 6.8e-18 64.5 2.2 8.9e-11 41.7 0.0 4.4 4 1 1 5 5 5 3 Fibronectin type III domain IL6Ra-bind PF09240.5 KFM02123.1 - 2.6e-12 46.7 5.8 3.7e-07 30.2 0.1 2.5 2 0 0 2 2 2 2 Interleukin-6 receptor alpha chain, binding Tissue_fac PF01108.12 KFM02123.1 - 3.9e-09 36.1 5.0 1.5e-06 27.9 0.0 3.5 2 1 1 3 3 3 2 Tissue factor EpoR_lig-bind PF09067.5 KFM02123.1 - 2.2e-06 27.6 1.3 0.00089 19.2 0.0 3.3 3 0 0 3 3 3 1 Erythropoietin receptor, ligand binding IL4Ra_N PF09238.5 KFM02123.1 - 2.4e-05 24.3 5.2 0.13 12.3 0.1 3.3 3 1 1 4 4 4 2 Interleukin-4 receptor alpha chain, N-terminal IL12p40_C PF10420.4 KFM02123.1 - 0.011 15.8 1.8 1.9 8.6 0.1 2.7 2 0 0 2 2 2 0 Cytokine interleukin-12p40 C-terminus TEX33 PF15400.1 KFM02124.1 - 1.4e-32 112.9 0.1 1.5e-32 112.9 0.0 1.0 1 0 0 1 1 1 1 Testis-expressed sequence 33 protein family Rhodanese PF00581.15 KFM02126.1 - 9.7e-33 112.8 0.0 1.6e-17 63.9 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain B12D PF06522.6 KFM02126.1 - 0.045 13.4 0.1 0.091 12.4 0.1 1.4 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit BTB_2 PF02214.17 KFM02127.1 - 1.9e-22 79.2 0.0 3e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KFM02127.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain DUF4206 PF13901.1 KFM02127.1 - 0.051 13.1 0.5 1.1 8.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4206) Trypsin PF00089.21 KFM02128.1 - 9.3e-43 146.3 0.0 1e-42 146.2 0.0 1.0 1 0 0 1 1 1 1 Trypsin fn3 PF00041.16 KFM02129.1 - 6e-08 32.7 1.3 1e-07 31.9 0.9 1.4 1 1 0 1 1 1 1 Fibronectin type III domain DUF3943 PF13084.1 KFM02129.1 - 0.0095 15.4 0.1 0.015 14.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3943) C1q PF00386.16 KFM02130.1 - 1.3e-33 115.7 1.5 1.6e-33 115.4 1.0 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 KFM02130.1 - 8.7e-09 34.7 15.5 1.3e-08 34.2 10.7 1.1 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) 7tm_1 PF00001.16 KFM02131.1 - 2.3e-66 223.5 19.5 3e-66 223.1 13.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM02131.1 - 7.3e-12 44.9 11.6 9e-12 44.6 8.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM02131.1 - 5.3e-07 29.0 7.7 7.8e-07 28.4 5.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.4 KFM02131.1 - 2.9e-06 26.6 5.2 2.9e-06 26.6 3.6 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.4 KFM02131.1 - 9.9e-05 21.6 11.8 0.013 14.6 8.2 2.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Serpentine_r_xa PF03383.10 KFM02131.1 - 0.00025 20.8 1.2 0.00025 20.8 0.8 2.8 2 1 1 3 3 3 1 Caenorhabditis serpentine receptor-like protein, class xa DUF2028 PF09667.5 KFM02131.1 - 0.049 13.7 0.0 0.077 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2028) TAS2R PF05296.8 KFM02131.1 - 0.15 10.8 11.6 0.56 9.0 8.1 1.9 1 1 0 1 1 1 0 Mammalian taste receptor protein (TAS2R) Rab5ip PF07019.7 KFM02131.1 - 0.2 11.8 3.4 0.16 12.1 0.4 2.3 2 0 0 2 2 2 0 Rab5-interacting protein (Rab5ip) Dicty_CAR PF05462.6 KFM02131.1 - 0.66 8.8 15.2 1.7 7.4 10.6 1.8 1 1 0 1 1 1 0 Slime mold cyclic AMP receptor Ras PF00071.17 KFM02132.1 - 5.1e-54 182.0 0.0 5.8e-54 181.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM02132.1 - 2.3e-16 60.3 0.0 3.1e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM02132.1 - 1.8e-07 30.5 0.0 3.1e-07 29.7 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFM02132.1 - 0.0035 16.8 0.0 0.034 13.5 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Sec7 PF01369.15 KFM02133.1 - 2e-64 216.8 0.0 3.1e-64 216.1 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH PF00169.24 KFM02133.1 - 7.8e-24 83.8 0.0 1.3e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KFM02133.1 - 1.1e-07 32.0 0.1 2.8e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.1 KFM02133.1 - 0.0024 17.9 0.0 0.21 11.6 0.1 2.4 1 1 1 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.1 KFM02133.1 - 0.008 16.0 0.0 0.021 14.7 0.0 1.8 1 1 0 1 1 1 1 PH domain Syntaxin-6_N PF09177.6 KFM02133.1 - 0.1 13.0 0.0 0.44 10.9 0.0 2.1 1 0 0 1 1 1 0 Syntaxin 6, N-terminal LRR_8 PF13855.1 KFM02134.1 - 3e-21 74.9 10.3 1.3e-15 56.8 0.6 3.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KFM02134.1 - 2.1e-08 33.5 13.0 0.00091 18.7 0.1 3.8 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFM02134.1 - 2.7e-07 30.3 1.0 8.8e-07 28.6 0.3 2.1 2 0 0 2 2 2 1 Leucine rich repeats (6 copies) fn3 PF00041.16 KFM02134.1 - 0.0087 16.1 0.2 0.022 14.8 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III domain LRR_1 PF00560.28 KFM02134.1 - 0.0091 15.8 15.5 2.3 8.5 0.4 5.5 6 0 0 6 6 6 2 Leucine Rich Repeat Herpes_gE PF02480.11 KFM02134.1 - 0.0092 14.2 0.3 0.015 13.6 0.2 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E LRR_6 PF13516.1 KFM02134.1 - 0.013 15.4 11.5 2.1 8.6 0.0 4.6 4 1 1 5 5 5 0 Leucine Rich repeat DUF2816 PF10992.3 KFM02134.1 - 0.052 13.1 0.3 0.12 12.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2816) Fringe PF02434.11 KFM02135.1 - 9.5e-112 372.2 0.0 1.1e-111 372.0 0.0 1.0 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.16 KFM02135.1 - 0.0041 16.7 0.0 0.0058 16.2 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase DUF2785 PF10978.3 KFM02135.1 - 0.088 12.2 0.1 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2785) CARD PF00619.16 KFM02136.1 - 1.4e-20 72.8 0.0 6.6e-20 70.7 0.0 2.3 1 0 0 1 1 1 1 Caspase recruitment domain Guanylate_kin PF00625.16 KFM02136.1 - 0.00068 19.1 1.8 0.0011 18.4 0.0 2.0 2 0 0 2 2 2 1 Guanylate kinase DUF1664 PF07889.7 KFM02136.1 - 0.012 15.4 3.0 0.012 15.4 2.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) Flavi_capsid PF01003.14 KFM02136.1 - 0.016 14.7 0.5 0.39 10.2 0.2 2.3 2 0 0 2 2 2 0 Flavivirus capsid protein C ATG16 PF08614.6 KFM02136.1 - 0.36 10.6 33.2 0.11 12.2 1.9 3.4 2 1 0 3 3 3 0 Autophagy protein 16 (ATG16) Tropomyosin PF00261.15 KFM02136.1 - 4.2 6.3 34.3 0.11 11.5 8.8 3.2 2 1 1 3 3 3 0 Tropomyosin BORG_CEP PF14957.1 KFM02137.1 - 2.6e-16 60.6 0.8 8.6e-09 36.3 1.0 2.2 1 1 1 2 2 2 2 Cdc42 effector PBD PF00786.23 KFM02137.1 - 1.2e-07 31.9 0.8 2.7e-07 30.8 0.6 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain Gal-bind_lectin PF00337.17 KFM02138.1 - 2e-31 108.1 0.0 2.1e-31 108.0 0.0 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin DUF4304 PF14137.1 KFM02138.1 - 0.011 15.8 0.0 0.014 15.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4304) DUF2835 PF11197.3 KFM02138.1 - 0.099 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2835) VHS PF00790.14 KFM02139.1 - 2.1e-36 124.6 1.2 1.5e-35 121.8 0.0 2.3 2 1 0 2 2 2 1 VHS domain GAT PF03127.9 KFM02139.1 - 1.3e-34 118.2 3.9 1.3e-34 118.2 2.7 2.1 2 0 0 2 2 2 1 GAT domain Alpha_adaptinC2 PF02883.15 KFM02139.1 - 3e-28 98.4 0.4 1e-27 96.7 0.1 2.0 2 0 0 2 2 2 1 Adaptin C-terminal domain DUF1313 PF07011.6 KFM02139.1 - 0.0009 18.8 3.0 0.05 13.2 0.6 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1313) Ferritin PF00210.19 KFM02139.1 - 0.03 14.0 1.6 0.15 11.8 0.9 2.0 2 0 0 2 2 2 0 Ferritin-like domain DUF1910 PF08928.5 KFM02139.1 - 0.099 12.6 0.4 0.18 11.8 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) Fib_alpha PF08702.5 KFM02139.1 - 0.64 10.1 5.5 1.3 9.1 3.8 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family RhoGAP PF00620.22 KFM02140.1 - 2.5e-42 144.0 0.0 5.3e-42 143.0 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain BAR PF03114.13 KFM02140.1 - 5.8e-24 84.8 2.8 9.9e-24 84.1 2.0 1.3 1 0 0 1 1 1 1 BAR domain Hydrolase_like PF13242.1 KFM02140.1 - 2.1e-19 68.9 0.0 4.2e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 KFM02140.1 - 2.5e-06 27.8 0.0 5.4e-05 23.4 0.0 2.8 3 1 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFM02140.1 - 1.6e-05 25.4 0.0 3.2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Mating_N PF12731.2 KFM02140.1 - 0.025 14.4 2.5 1 9.3 0.0 3.1 3 1 0 3 3 3 0 Mating-type protein beta 1 PGP_phosphatase PF09419.5 KFM02140.1 - 0.038 13.3 0.2 0.085 12.2 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Gal-bind_lectin PF00337.17 KFM02141.1 - 2.7e-29 101.1 0.0 3.2e-29 100.9 0.0 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin TOBE PF03459.12 KFM02141.1 - 0.064 13.3 0.0 4.4 7.4 0.0 2.3 2 0 0 2 2 2 0 TOBE domain ArfGap PF01412.13 KFM02142.1 - 4.8e-37 126.3 0.2 1e-36 125.2 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.24 KFM02142.1 - 4.1e-17 62.2 0.4 2.4e-08 34.1 0.1 2.9 2 1 0 2 2 2 2 PH domain PH_11 PF15413.1 KFM02142.1 - 3.3e-11 43.4 0.7 1.1e-06 28.9 0.1 3.3 2 1 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 KFM02142.1 - 2.3e-06 27.5 1.4 0.012 15.7 0.0 2.8 3 1 0 3 3 3 2 Pleckstrin homology domain PH_3 PF14593.1 KFM02142.1 - 5.9e-05 22.8 0.4 0.0077 16.1 0.0 3.1 2 1 0 2 2 2 1 PH domain Nop25 PF09805.4 KFM02143.1 - 6.2e-20 71.6 5.0 6.2e-20 71.6 3.5 2.1 1 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) Hepatitis_core PF00906.15 KFM02143.1 - 0.28 10.8 6.5 0.57 9.8 4.5 1.4 1 0 0 1 1 1 0 Hepatitis core antigen DUF572 PF04502.8 KFM02143.1 - 0.54 9.4 11.8 0.74 8.9 8.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) RAP1 PF07218.6 KFM02143.1 - 7.6 4.4 6.4 11 4.0 4.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Mnd1 PF03962.10 KFM02143.1 - 7.9 6.0 10.0 1.8 8.2 3.0 2.0 2 0 0 2 2 2 0 Mnd1 family PH PF00169.24 KFM02144.1 - 2.1e-14 53.5 0.1 5.6e-14 52.2 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KFM02144.1 - 0.00014 22.0 0.3 0.00014 22.0 0.2 3.3 3 1 0 3 3 3 1 Pleckstrin homology domain HALZ PF02183.13 KFM02144.1 - 0.012 15.3 0.4 0.012 15.3 0.3 5.6 6 0 0 6 6 6 0 Homeobox associated leucine zipper TBPIP PF07106.8 KFM02144.1 - 6.9 6.1 34.9 0.28 10.7 3.5 4.6 4 1 1 5 5 5 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Linker_histone PF00538.14 KFM02145.1 - 9e-20 70.5 3.0 1.9e-19 69.5 2.1 1.5 1 0 0 1 1 1 1 linker histone H1 and H5 family CDC27 PF09507.5 KFM02145.1 - 1.6 7.9 28.0 1.6 7.8 19.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Aminotran_1_2 PF00155.16 KFM02146.1 - 4.8e-74 249.4 0.0 5.3e-74 249.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KFM02146.1 - 5.8e-09 35.1 0.0 1.8e-08 33.5 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 KFM02146.1 - 2.4e-05 22.7 0.0 3.7e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SHMT PF00464.14 KFM02146.1 - 0.00013 20.4 0.0 0.00034 19.0 0.0 1.7 1 1 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 KFM02146.1 - 0.00047 19.4 0.0 0.00067 18.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KFM02146.1 - 0.053 12.5 0.5 0.49 9.3 0.3 2.1 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family OKR_DC_1 PF01276.15 KFM02146.1 - 0.11 11.0 0.0 1.6 7.1 0.0 2.1 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain 7tm_1 PF00001.16 KFM02147.1 - 1e-57 195.2 18.7 1.2e-57 195.0 12.9 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.4 KFM02147.1 - 3.5e-09 36.2 13.0 3.8e-07 29.5 9.0 2.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.4 KFM02147.1 - 0.0043 16.2 16.7 0.0054 15.8 11.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv SecG PF03840.9 KFM02147.1 - 0.011 15.5 0.9 2.7 7.7 0.0 3.4 3 0 0 3 3 3 0 Preprotein translocase SecG subunit DUF420 PF04238.7 KFM02147.1 - 0.027 14.4 1.2 0.027 14.4 0.8 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF420) Flavi_capsid PF01003.14 KFM02147.1 - 0.074 12.6 0.1 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 Flavivirus capsid protein C Herpes_US9 PF06072.6 KFM02147.1 - 3.2 7.6 5.9 0.9 9.4 0.3 2.8 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 Ank PF00023.25 KFM02148.1 - 7.7e-26 88.5 7.9 1.5e-11 43.5 0.1 4.5 4 1 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 KFM02148.1 - 1.5e-24 86.1 0.3 1.3e-12 47.8 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFM02148.1 - 3.1e-21 74.9 5.8 6.1e-13 48.5 0.8 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFM02148.1 - 3.8e-19 68.6 0.7 9.9e-09 35.4 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM02148.1 - 4.5e-15 54.2 0.4 1.7e-06 27.7 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat DUF3510 PF12022.3 KFM02148.1 - 0.1 12.7 0.6 0.15 12.1 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) DUF3926 PF13080.1 KFM02148.1 - 0.14 11.6 2.1 0.21 11.1 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3926) Paf67 PF10255.4 KFM02149.1 - 5.4e-171 568.9 12.5 7.8e-171 568.4 8.7 1.2 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 Apc3 PF12895.2 KFM02149.1 - 0.00074 19.6 0.2 0.0029 17.6 0.2 2.1 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 KFM02149.1 - 0.0016 18.1 0.4 0.037 13.9 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFM02149.1 - 0.011 15.2 0.3 0.41 10.3 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 KFM02149.1 - 0.012 15.4 0.3 0.048 13.6 0.1 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat SPG48 PF14764.1 KFM02149.1 - 0.036 12.5 0.3 0.12 10.8 0.1 1.9 2 1 0 2 2 2 0 AP-5 complex subunit, vesicle trafficking TPR_16 PF13432.1 KFM02149.1 - 0.13 12.9 0.0 0.45 11.2 0.0 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat DUF3585 PF12130.3 KFM02150.1 - 1.9e-49 167.1 11.5 3.1e-49 166.4 8.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3585) LIM PF00412.17 KFM02150.1 - 4.1e-08 33.1 4.0 8.3e-08 32.1 2.8 1.5 1 0 0 1 1 1 1 LIM domain CH PF00307.26 KFM02150.1 - 1.9e-06 27.8 0.0 4.2e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain Rieske PF00355.21 KFM02150.1 - 0.072 12.6 0.1 0.18 11.3 0.1 1.7 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain UPF0193 PF05250.6 KFM02151.1 - 3e-43 147.8 9.4 3.7e-43 147.5 6.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0193) Fzo_mitofusin PF04799.8 KFM02151.1 - 1.7 7.9 5.4 0.61 9.4 1.8 1.7 2 1 0 2 2 2 0 fzo-like conserved region RNA_pol_Rpb6 PF01192.17 KFM02152.1 - 5e-22 77.4 0.3 6.3e-22 77.0 0.2 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb6 Sox_N PF12444.3 KFM02153.1 - 6.8e-26 91.1 0.3 6.8e-26 91.1 0.2 2.6 3 1 0 3 3 3 1 Sox developmental protein N terminal HMG_box PF00505.14 KFM02153.1 - 2e-24 85.6 1.4 3.4e-24 84.8 1.0 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFM02153.1 - 4.9e-10 39.6 0.9 4.9e-10 39.6 0.6 1.7 2 0 0 2 2 2 1 HMG-box domain MAT_Alpha1 PF04769.7 KFM02153.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 Arfaptin PF06456.8 KFM02154.1 - 1.7e-84 282.7 1.5 2.7e-84 282.0 1.1 1.3 1 0 0 1 1 1 1 Arfaptin-like domain PDZ PF00595.19 KFM02154.1 - 1.1e-10 41.5 0.1 2e-10 40.7 0.1 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM02154.1 - 5.4e-06 26.2 0.3 3e-05 23.8 0.1 2.2 2 0 0 2 2 2 1 PDZ domain BAR PF03114.13 KFM02154.1 - 1.3e-05 24.8 1.7 3.7e-05 23.3 0.9 1.9 1 1 1 2 2 2 1 BAR domain GRASP55_65 PF04495.9 KFM02154.1 - 0.043 13.8 0.0 0.66 9.9 0.0 2.3 2 0 0 2 2 2 0 GRASP55/65 PDZ-like domain MFS_1 PF07690.11 KFM02155.1 - 1.1e-33 116.4 21.1 1.4e-33 116.1 14.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Rtf2 PF04641.7 KFM02155.1 - 0.18 10.9 3.6 0.26 10.4 2.5 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger IMD PF08397.6 KFM02156.1 - 1.8e-67 226.8 10.7 2.2e-67 226.5 7.4 1.1 1 0 0 1 1 1 1 IRSp53/MIM homology domain SH3_9 PF14604.1 KFM02156.1 - 7.1e-10 38.3 0.0 1.2e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFM02156.1 - 4e-05 23.0 0.0 7.8e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM02156.1 - 0.00012 21.3 0.0 0.00021 20.6 0.0 1.3 1 0 0 1 1 1 1 SH3 domain Ank_2 PF12796.2 KFM02157.1 - 1.4e-47 159.9 4.9 8.9e-16 58.0 0.1 4.0 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KFM02157.1 - 2.9e-38 127.7 7.2 1.2e-07 31.1 0.0 7.8 7 1 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.1 KFM02157.1 - 1.5e-30 102.1 4.6 1.3e-05 25.0 0.0 7.7 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.1 KFM02157.1 - 1.3e-27 95.6 2.0 4e-08 33.5 0.0 6.0 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM02157.1 - 9e-27 92.5 9.9 1.7e-07 31.2 0.0 8.0 3 1 6 9 9 9 6 Ankyrin repeats (many copies) Patatin PF01734.17 KFM02157.1 - 2.2e-19 70.1 1.1 8.9e-19 68.2 0.8 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase YfmQ PF10787.4 KFM02157.1 - 0.096 12.0 0.0 0.87 8.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein from bacillus cereus group bZIP_Maf PF03131.12 KFM02158.1 - 4.1e-24 84.7 8.4 4.7e-24 84.5 5.9 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.10 KFM02158.1 - 0.0051 16.5 9.1 0.006 16.3 5.6 1.7 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 KFM02158.1 - 0.0077 16.1 12.7 0.036 14.0 8.8 1.9 1 1 0 1 1 1 1 bZIP transcription factor MAD PF05557.8 KFM02158.1 - 0.012 13.8 0.9 0.013 13.6 0.6 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein DivIC PF04977.10 KFM02158.1 - 0.014 14.8 1.1 0.014 14.8 0.7 2.1 1 1 1 2 2 2 0 Septum formation initiator DUF972 PF06156.8 KFM02158.1 - 0.09 13.1 1.2 0.12 12.6 0.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 KFM02158.1 - 0.15 11.6 1.9 0.3 10.6 1.3 1.5 1 1 0 1 1 1 0 IncA protein Macoilin PF09726.4 KFM02158.1 - 0.16 10.2 1.6 0.16 10.1 1.1 1.0 1 0 0 1 1 1 0 Transmembrane protein HALZ PF02183.13 KFM02158.1 - 0.39 10.4 8.5 0.34 10.6 0.3 2.9 2 1 1 3 3 3 0 Homeobox associated leucine zipper GAS PF13851.1 KFM02158.1 - 0.52 9.4 5.2 1.1 8.4 3.6 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF904 PF06005.7 KFM02158.1 - 1.7 8.9 7.6 9.1 6.6 5.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Solute_trans_a PF03619.11 KFM02159.1 - 1.7e-98 329.3 19.4 2.1e-98 329.0 13.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF1282 PF06930.7 KFM02159.1 - 0.22 11.1 9.8 0.075 12.6 3.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) Pkinase PF00069.20 KFM02160.1 - 2.4e-32 112.1 0.0 3e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM02160.1 - 2.9e-12 46.2 0.0 3.9e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFM02160.1 - 0.0001 22.1 0.5 0.00064 19.5 0.0 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KFM02160.1 - 0.024 13.4 0.2 0.038 12.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase IRK PF01007.15 KFM02161.1 - 1.4e-169 563.2 0.0 1.7e-169 563.0 0.0 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 KFM02161.1 - 0.096 12.4 13.3 0.16 11.6 7.9 2.2 1 1 1 2 2 2 0 Ion channel Laminin_II PF06009.7 KFM02162.1 - 0.0002 21.1 6.4 0.002 17.9 3.2 2.0 1 1 1 2 2 2 1 Laminin Domain II ERM PF00769.14 KFM02162.1 - 0.0019 17.7 7.2 0.0023 17.5 5.0 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Tropomyosin PF00261.15 KFM02162.1 - 0.0026 16.8 9.5 0.0033 16.5 6.5 1.3 1 1 0 1 1 1 1 Tropomyosin DUF3972 PF13118.1 KFM02162.1 - 0.0047 17.0 2.9 0.045 13.8 0.0 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF3972) BRE1 PF08647.6 KFM02162.1 - 0.0068 16.3 6.6 0.0091 15.9 4.2 1.7 1 1 0 1 1 1 1 BRE1 E3 ubiquitin ligase GAS PF13851.1 KFM02162.1 - 0.018 14.2 6.9 0.024 13.8 4.8 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DASH_Dad4 PF08650.5 KFM02162.1 - 0.02 14.7 2.0 0.045 13.6 0.2 2.2 1 1 0 2 2 2 0 DASH complex subunit Dad4 CCDC155 PF14662.1 KFM02162.1 - 0.024 14.2 11.7 0.13 11.7 8.1 1.8 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 APG6 PF04111.7 KFM02162.1 - 0.032 13.2 6.8 0.039 13.0 4.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 CENP-Q PF13094.1 KFM02162.1 - 0.049 13.6 9.7 0.056 13.4 6.2 1.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TSC22 PF01166.13 KFM02162.1 - 0.054 13.4 4.4 0.29 11.1 0.3 2.9 3 0 0 3 3 3 0 TSC-22/dip/bun family DUF4200 PF13863.1 KFM02162.1 - 0.055 13.4 7.9 0.071 13.0 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Fib_alpha PF08702.5 KFM02162.1 - 0.077 13.1 5.9 0.32 11.1 3.1 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Reo_sigmaC PF04582.7 KFM02162.1 - 0.13 11.3 1.9 0.18 10.9 1.3 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF342 PF03961.8 KFM02162.1 - 0.31 9.4 3.4 0.35 9.2 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) bZIP_Maf PF03131.12 KFM02162.1 - 0.39 11.0 11.1 1.3 9.3 4.5 2.2 1 1 1 2 2 2 0 bZIP Maf transcription factor Lge1 PF11488.3 KFM02162.1 - 1.2 9.3 7.4 0.58 10.3 2.1 2.3 1 1 2 3 3 3 0 Transcriptional regulatory protein LGE1 ADIP PF11559.3 KFM02162.1 - 1.5 8.7 12.2 1.6 8.6 1.9 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Kinesin-relat_1 PF12711.2 KFM02162.1 - 2.9 8.3 9.9 3.2 8.1 1.3 2.9 1 1 2 3 3 3 0 Kinesin motor IncA PF04156.9 KFM02162.1 - 5.2 6.6 15.0 4.8 6.7 8.6 1.9 1 1 1 2 2 2 0 IncA protein Cep57_CLD_2 PF14197.1 KFM02162.1 - 6.4 6.8 10.7 0.89 9.5 0.3 2.7 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 ER_lumen_recept PF00810.13 KFM02163.1 - 5.5e-57 192.3 11.1 9.7e-57 191.5 7.7 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 KFM02163.1 - 0.026 14.0 10.4 0.046 13.2 0.4 3.2 3 1 0 3 3 3 0 PQ loop repeat Cation_ATPase_C PF00689.16 KFM02163.1 - 4.1 6.9 11.5 0.1 12.0 2.3 2.2 2 1 1 3 3 3 0 Cation transporting ATPase, C-terminus DEAD PF00270.24 KFM02164.1 - 2.7e-45 153.9 0.0 5.1e-44 149.7 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFM02164.1 - 6.7e-26 89.9 0.0 1.4e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFM02164.1 - 0.0075 16.1 0.0 0.031 14.1 0.0 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Ferritin PF00210.19 KFM02164.1 - 0.0093 15.7 0.8 0.032 13.9 0.5 1.9 1 1 0 1 1 1 1 Ferritin-like domain Helicase_C_2 PF13307.1 KFM02164.1 - 0.056 13.3 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain Rad51 PF08423.6 KFM02165.1 - 3.2e-121 403.0 0.0 4.1e-121 402.7 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KFM02165.1 - 5e-10 39.0 0.0 7.1e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 KFM02165.1 - 6e-10 38.6 0.0 8.2e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 KFM02165.1 - 7.4e-07 28.5 0.0 1.5e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.1 KFM02165.1 - 2.6e-06 27.4 0.1 5.6e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain DUF128 PF01995.11 KFM02165.1 - 0.0062 15.5 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF128 HHH PF00633.18 KFM02165.1 - 0.071 12.8 0.0 0.61 9.9 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif Chibby PF14645.1 KFM02166.1 - 6.3e-51 171.1 0.6 7.2e-51 170.9 0.4 1.0 1 0 0 1 1 1 1 Chibby family Taxilin PF09728.4 KFM02166.1 - 0.0015 17.6 1.9 0.0018 17.4 1.3 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein UPF0242 PF06785.6 KFM02166.1 - 0.0017 17.1 1.7 0.0018 17.0 1.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) DUF972 PF06156.8 KFM02166.1 - 0.029 14.7 3.8 0.044 14.1 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF2051 PF09738.4 KFM02166.1 - 0.04 13.1 5.4 0.051 12.8 3.7 1.1 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) Shugoshin_N PF07558.6 KFM02166.1 - 1 9.1 11.0 0.33 10.6 3.0 2.4 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region bZIP_2 PF07716.10 KFM02166.1 - 1.1 9.1 10.8 0.15 11.8 3.7 2.1 2 0 0 2 2 2 0 Basic region leucine zipper TMF_DNA_bd PF12329.3 KFM02166.1 - 2.8 7.8 10.0 4.2 7.2 6.9 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 KFM02166.1 - 3.5 7.1 6.4 1.9 8.0 2.1 1.9 1 1 1 2 2 2 0 Septum formation initiator TSC22 PF01166.13 KFM02166.1 - 4.7 7.2 9.1 0.57 10.1 1.6 2.1 1 1 1 2 2 2 0 TSC-22/dip/bun family Josephin PF02099.12 KFM02167.1 - 4.3e-28 97.9 0.3 3.5e-27 94.9 0.2 2.0 1 1 0 1 1 1 1 Josephin GTP_EFTU PF00009.22 KFM02168.1 - 3.4e-27 95.0 0.0 5.4e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KFM02168.1 - 3.7e-18 65.5 0.7 8.9e-18 64.2 0.0 2.1 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KFM02168.1 - 2.9e-07 30.5 0.3 1.8e-06 27.9 0.1 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 KFM02168.1 - 0.00023 20.6 0.0 1 8.8 0.0 3.6 2 1 1 3 3 3 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 KFM02168.1 - 0.0017 18.2 0.0 0.0039 17.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KFM02168.1 - 0.0041 17.5 0.1 0.045 14.2 0.0 2.7 2 1 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 KFM02168.1 - 0.083 12.7 0.3 0.65 9.7 0.1 2.3 1 1 1 2 2 2 0 Dynamin family Arf PF00025.16 KFM02168.1 - 0.14 11.3 0.1 12 5.0 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family Sad1_UNC PF07738.8 KFM02169.1 - 1e-44 151.6 0.0 1.5e-44 151.0 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Spc7 PF08317.6 KFM02169.1 - 0.0054 15.4 2.4 0.0098 14.5 1.7 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF1640 PF07798.6 KFM02169.1 - 0.0074 16.3 0.7 0.012 15.6 0.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) Leu_zip PF15294.1 KFM02169.1 - 0.011 14.8 4.7 0.021 13.9 3.3 1.3 1 0 0 1 1 1 0 Leucine zipper DUF2357 PF09823.4 KFM02169.1 - 0.12 11.4 0.2 0.73 8.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2357) YlqD PF11068.3 KFM02169.1 - 0.24 11.4 5.8 0.56 10.2 4.0 1.6 1 0 0 1 1 1 0 YlqD protein APG6 PF04111.7 KFM02169.1 - 2.3 7.1 6.1 4.1 6.3 4.3 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4618 PF15397.1 KFM02169.1 - 4.3 6.5 6.9 0.58 9.4 1.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Mnd1 PF03962.10 KFM02169.1 - 4.9 6.7 6.2 1.7 8.2 2.0 1.9 1 1 1 2 2 2 0 Mnd1 family DUF1193 PF06702.7 KFM02170.1 - 8.9e-106 352.2 0.0 1.1e-105 351.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1193) FAM198 PF15051.1 KFM02170.1 - 0.044 12.4 0.0 0.075 11.7 0.0 1.4 1 0 0 1 1 1 0 FAM198 protein Dynein_light PF01221.13 KFM02171.1 - 8.6e-29 99.3 0.2 9.9e-29 99.1 0.2 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 DUF3109 PF11307.3 KFM02171.1 - 0.032 13.7 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3109) GARS_A PF01071.14 KFM02171.1 - 0.051 13.1 0.0 0.056 13.0 0.0 1.1 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Pentaxin PF00354.12 KFM02172.1 - 5.1e-37 127.2 0.0 6.9e-37 126.7 0.0 1.2 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.1 KFM02172.1 - 2.4e-14 53.8 0.0 4e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Chromo PF00385.19 KFM02173.1 - 2e-11 43.3 1.0 4.2e-11 42.3 0.7 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PDGF PF00341.12 KFM02174.1 - 3.2e-23 81.6 12.1 5.9e-23 80.7 8.4 1.4 1 0 0 1 1 1 1 PDGF/VEGF domain PDGF_N PF04692.8 KFM02174.1 - 0.18 12.3 1.0 1.6 9.2 0.0 2.4 2 0 0 2 2 2 0 Platelet-derived growth factor, N terminal region PDGF PF00341.12 KFM02175.1 - 4.5e-23 81.1 12.1 8.6e-23 80.2 8.4 1.5 1 0 0 1 1 1 1 PDGF/VEGF domain PDGF_N PF04692.8 KFM02175.1 - 1.2e-19 70.6 3.3 1.9e-19 69.9 0.2 2.4 2 0 0 2 2 2 1 Platelet-derived growth factor, N terminal region Ribosomal_L3 PF00297.17 KFM02176.1 - 1.8e-123 411.1 9.9 2.1e-123 410.8 6.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 DUF3903 PF13043.1 KFM02176.1 - 0.033 13.6 0.9 0.16 11.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3903) Glyco_transf_17 PF04724.8 KFM02178.1 - 1.3e-131 438.8 0.0 1.7e-131 438.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 17 hEGF PF12661.2 KFM02178.1 - 0.0064 16.5 3.7 0.021 14.8 2.5 2.0 1 0 0 1 1 1 1 Human growth factor-like EGF EGF_2 PF07974.8 KFM02178.1 - 0.12 12.5 0.8 0.29 11.3 0.6 1.6 1 0 0 1 1 1 0 EGF-like domain Mab-21 PF03281.9 KFM02179.1 - 1.6e-32 112.8 0.0 3.2e-30 105.2 0.0 2.1 1 1 0 1 1 1 1 Mab-21 protein bZIP_1 PF00170.16 KFM02180.1 - 3e-14 52.7 14.1 3e-14 52.7 9.8 2.2 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KFM02180.1 - 7.9e-08 32.0 12.0 1.7e-07 30.9 8.3 1.5 1 0 0 1 1 1 1 Basic region leucine zipper IncA PF04156.9 KFM02180.1 - 0.0071 15.9 5.7 0.011 15.2 3.9 1.2 1 0 0 1 1 1 1 IncA protein Phage_GPO PF05929.6 KFM02180.1 - 0.032 13.4 2.0 0.055 12.7 1.4 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase BLOC1_2 PF10046.4 KFM02180.1 - 0.067 13.3 4.5 0.14 12.2 3.1 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.7 KFM02180.1 - 0.17 11.6 5.9 0.32 10.7 4.1 1.3 1 0 0 1 1 1 0 Laminin Domain II bZIP_Maf PF03131.12 KFM02180.1 - 0.38 11.0 9.3 0.67 10.2 6.4 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor AAA_13 PF13166.1 KFM02180.1 - 0.99 7.7 9.1 1.4 7.3 6.3 1.1 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 KFM02180.1 - 1.1 8.2 9.4 1.6 7.6 6.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 KFM02180.1 - 2.2 6.0 6.5 3 5.5 4.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 KFM02180.1 - 5.6 6.5 9.7 21 4.6 6.7 1.9 1 1 0 1 1 1 0 Septum formation initiator Kdo PF06293.9 KFM02181.1 - 0.068 12.2 0.1 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1669 PF07894.7 KFM02182.1 - 2.6e-86 289.3 0.0 3.9e-86 288.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1669) PLDc_2 PF13091.1 KFM02182.1 - 1.1e-06 28.3 0.0 2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 PLD-like domain IncA PF04156.9 KFM02182.1 - 1.5 8.3 3.6 2.8 7.4 2.5 1.3 1 0 0 1 1 1 0 IncA protein Ago_hook PF10427.4 KFM02183.1 - 1.6e-12 47.6 30.0 1.6e-12 47.6 20.8 10.0 3 2 6 9 9 9 1 Argonaute hook RRM_5 PF13893.1 KFM02183.1 - 4.5e-05 23.2 0.0 7.7e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFM02183.1 - 0.0018 17.8 0.0 0.0031 17.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM02183.1 - 0.059 13.3 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Lyase_1 PF00206.15 KFM02184.1 - 7.4e-27 94.3 0.0 1.1e-26 93.7 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 KFM02184.1 - 2.4e-16 59.5 0.0 7.1e-16 57.9 0.0 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus DUF4089 PF13318.1 KFM02184.1 - 0.044 14.0 0.3 0.16 12.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4089) DUF1331 PF07048.6 KFM02184.1 - 0.05 13.0 0.2 0.097 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) RabGAP-TBC PF00566.13 KFM02185.1 - 2.9e-48 164.1 1.6 4.3e-48 163.6 1.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RUN PF02759.14 KFM02185.1 - 9.2e-31 106.3 0.1 2.2e-30 105.1 0.1 1.7 1 0 0 1 1 1 1 RUN domain SH3_1 PF00018.23 KFM02185.1 - 2.9e-12 45.7 0.1 7.1e-12 44.5 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFM02185.1 - 9e-11 41.1 0.0 2.7e-10 39.6 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFM02185.1 - 5e-10 38.7 0.0 1.1e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain RPEL PF02755.10 KFM02186.1 - 7.7e-28 95.0 8.6 6.3e-09 34.8 0.0 3.7 3 0 0 3 3 3 3 RPEL repeat SAP PF02037.22 KFM02186.1 - 4.8e-12 45.0 0.5 1.1e-11 43.9 0.4 1.7 1 0 0 1 1 1 1 SAP domain Mito_carr PF00153.22 KFM02187.1 - 1.7e-53 178.3 0.3 4.3e-23 80.8 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein TPR_11 PF13414.1 KFM02188.1 - 9.1e-24 82.8 2.1 3.3e-13 49.0 0.1 2.6 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 KFM02188.1 - 8.7e-13 47.2 1.5 2.7e-05 23.5 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFM02188.1 - 2.1e-11 42.7 8.8 0.0052 16.5 0.9 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFM02188.1 - 1.8e-09 37.9 3.7 2.2e-06 28.2 0.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFM02188.1 - 1.1e-06 28.3 0.2 0.0024 17.9 0.0 3.0 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 KFM02188.1 - 3.7e-06 26.7 3.4 4e-06 26.5 0.3 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFM02188.1 - 0.00017 21.9 8.1 0.077 13.6 0.0 4.4 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFM02188.1 - 0.00076 19.3 4.2 0.013 15.3 0.1 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFM02188.1 - 0.0015 18.7 1.0 0.058 13.7 0.0 3.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFM02188.1 - 0.028 14.8 0.2 46 4.7 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFM02188.1 - 0.071 12.9 0.2 20 5.2 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat BCA_ABC_TP_C PF12399.3 KFM02188.1 - 0.11 12.2 0.1 10 5.9 0.0 3.6 3 0 0 3 3 3 0 Branched-chain amino acid ATP-binding cassette transporter OmpH PF03938.9 KFM02188.1 - 0.12 12.3 3.8 0.088 12.7 0.3 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) TPR_7 PF13176.1 KFM02188.1 - 0.82 9.6 3.4 42 4.2 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2203 PF09969.4 KFM02188.1 - 4.5 7.5 7.3 1.3 9.2 2.3 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF3216 PF11505.3 KFM02188.1 - 6.5 6.6 7.2 12 5.8 2.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3216) NYD-SP12_N PF15015.1 KFM02188.1 - 7.3 4.6 10.0 0.32 9.1 0.0 2.3 1 1 1 2 2 2 0 Spermatogenesis-associated, N-terminal Peptidase_M24 PF00557.19 KFM02189.1 - 8.6e-56 188.7 0.0 1.1e-55 188.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KFM02189.1 - 1.3e-36 124.9 0.0 2.9e-36 123.8 0.0 1.6 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain zf-rbx1 PF12678.2 KFM02190.1 - 3e-33 113.7 14.5 3.4e-33 113.5 10.0 1.0 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KFM02190.1 - 8.7e-16 57.5 10.7 1e-15 57.2 7.4 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 KFM02190.1 - 5.4e-08 32.5 12.4 4.3e-07 29.6 8.6 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KFM02190.1 - 0.00032 20.3 12.2 0.0069 16.0 8.5 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM02190.1 - 0.00051 19.6 10.3 0.0026 17.3 3.2 2.4 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM02190.1 - 0.0077 16.2 12.6 0.019 14.9 5.7 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KFM02190.1 - 0.11 12.4 9.4 0.69 9.9 6.6 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 KFM02190.1 - 0.18 11.5 6.8 0.66 9.7 2.3 2.2 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_5 PF14634.1 KFM02190.1 - 0.21 11.3 12.9 2.4 7.9 9.0 2.5 1 1 0 1 1 1 0 zinc-RING finger domain DUF4001 PF13165.1 KFM02190.1 - 0.41 10.3 5.0 0.59 9.8 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4001) zf-RING_6 PF14835.1 KFM02190.1 - 1.6 8.5 5.5 0.71 9.7 0.2 2.1 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-HC5HC2H_2 PF13832.1 KFM02190.1 - 1.9 8.5 11.4 5.4 7.0 7.9 1.7 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KFM02190.1 - 4.5 7.4 12.5 3.2e+02 1.5 8.8 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-C3HC4_4 PF15227.1 KFM02190.1 - 8.8 6.3 9.9 0.49 10.3 0.4 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING KAT11 PF08214.6 KFM02191.1 - 6.3e-80 268.8 0.2 1.4e-79 267.7 0.2 1.6 1 0 0 1 1 1 1 Histone acetylation protein KIX PF02172.11 KFM02191.1 - 1.5e-41 140.3 1.0 3.4e-41 139.1 0.7 1.7 1 0 0 1 1 1 1 KIX domain zf-TAZ PF02135.11 KFM02191.1 - 2.1e-35 120.5 69.2 3.6e-21 74.9 14.0 3.5 3 0 0 3 3 3 2 TAZ zinc finger Creb_binding PF09030.5 KFM02191.1 - 2.9e-33 114.1 21.4 2.9e-33 114.1 14.9 14.9 8 4 6 15 15 15 1 Creb binding DUF902 PF06001.8 KFM02191.1 - 2.4e-24 85.1 6.8 2.4e-24 85.1 4.7 2.5 2 0 0 2 2 2 1 Domain of Unknown Function (DUF902) Bromodomain PF00439.20 KFM02191.1 - 1.3e-18 66.7 0.0 2.7e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 Bromodomain ZZ PF00569.12 KFM02191.1 - 8.2e-14 50.8 14.2 8.2e-14 50.8 9.8 3.5 4 0 0 4 4 4 1 Zinc finger, ZZ type Npa1 PF11707.3 KFM02191.1 - 0.0015 17.5 0.0 0.0026 16.8 0.0 1.3 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal DUF4131 PF13567.1 KFM02192.1 - 2.8 7.3 5.2 4 6.8 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) MBT PF02820.13 KFM02193.1 - 1.1e-93 307.2 5.2 3.1e-30 103.8 0.2 4.2 4 0 0 4 4 4 4 mbt repeat Calci_bind_CcbP PF11535.3 KFM02193.1 - 0.021 15.0 0.3 6.3 7.1 0.0 3.6 4 0 0 4 4 4 0 Calcium binding RanGAP1_C PF07834.6 KFM02194.1 - 1.6e-69 232.9 0.5 2.9e-69 232.1 0.3 1.4 1 0 0 1 1 1 1 RanGAP1 C-terminal domain LRR_6 PF13516.1 KFM02194.1 - 7e-22 75.0 1.9 0.16 12.0 0.2 9.1 9 0 0 9 9 9 5 Leucine Rich repeat LRR_1 PF00560.28 KFM02194.1 - 5.5e-08 31.7 0.1 7.8 6.9 0.1 6.4 6 0 0 6 6 5 0 Leucine Rich Repeat LRR_4 PF12799.2 KFM02194.1 - 2.9e-05 23.5 1.6 1.6 8.4 0.0 5.1 5 1 0 5 5 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM02194.1 - 5e-05 22.9 3.2 0.026 14.2 0.2 4.6 4 1 1 5 5 5 1 Leucine rich repeat LRR_7 PF13504.1 KFM02194.1 - 0.00015 21.4 4.7 11 6.7 0.0 5.7 6 0 0 6 6 5 0 Leucine rich repeat Nop14 PF04147.7 KFM02194.1 - 0.00075 17.5 8.3 0.001 17.0 5.8 1.2 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.9 KFM02194.1 - 0.01 13.8 3.1 0.015 13.3 2.2 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.5 KFM02194.1 - 0.017 14.2 5.8 0.024 13.7 4.0 1.3 1 0 0 1 1 1 0 BUD22 Pox_Ag35 PF03286.9 KFM02194.1 - 0.021 14.3 2.2 0.034 13.6 1.5 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Sigma70_ner PF04546.8 KFM02194.1 - 0.049 13.2 12.8 0.1 12.1 8.9 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Prothymosin PF03247.9 KFM02194.1 - 0.053 13.6 25.5 0.14 12.3 17.6 1.7 1 0 0 1 1 1 0 Prothymosin/parathymosin family MCR_beta_N PF02783.10 KFM02194.1 - 0.055 12.9 0.1 0.13 11.6 0.1 1.6 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, N-terminal domain Tim54 PF11711.3 KFM02194.1 - 0.16 10.5 2.2 0.24 9.9 1.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CobT PF06213.7 KFM02194.1 - 0.19 10.7 14.1 0.33 10.0 9.8 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RRN3 PF05327.6 KFM02194.1 - 0.25 9.4 2.1 0.34 8.9 1.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF1840 PF08895.6 KFM02194.1 - 0.36 10.8 4.0 0.53 10.3 1.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) SDA1 PF05285.7 KFM02194.1 - 0.42 9.8 12.1 0.65 9.2 8.4 1.2 1 0 0 1 1 1 0 SDA1 Ycf1 PF05758.7 KFM02194.1 - 0.44 8.1 1.8 0.55 7.8 1.2 1.1 1 0 0 1 1 1 0 Ycf1 Vfa1 PF08432.5 KFM02194.1 - 1 9.3 7.6 1.7 8.6 5.3 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2457 PF10446.4 KFM02194.1 - 1.1 7.9 13.5 1.4 7.5 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF3381 PF11861.3 KFM02194.1 - 1.4 8.3 15.1 3.1 7.2 10.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) TEX19 PF15553.1 KFM02194.1 - 1.9 8.3 6.2 3.5 7.4 4.3 1.4 1 0 0 1 1 1 0 Testis-expressed protein 19 XAP5 PF04921.9 KFM02194.1 - 2.5 7.6 6.8 4.3 6.8 4.7 1.3 1 0 0 1 1 1 0 XAP5, circadian clock regulator Mpp10 PF04006.7 KFM02194.1 - 2.7 6.2 20.8 3.9 5.7 14.4 1.1 1 0 0 1 1 1 0 Mpp10 protein NOA36 PF06524.7 KFM02194.1 - 3.1 6.9 11.0 5 6.3 7.6 1.2 1 0 0 1 1 1 0 NOA36 protein DUF2890 PF11081.3 KFM02194.1 - 3.6 7.5 15.7 6.5 6.7 10.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF1510 PF07423.6 KFM02194.1 - 3.7 6.8 13.1 6 6.1 9.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) YqfQ PF14181.1 KFM02194.1 - 4.1 7.4 9.3 9 6.3 6.4 1.5 1 0 0 1 1 1 0 YqfQ-like protein BSP_II PF05432.6 KFM02194.1 - 4.7 6.3 18.0 8.5 5.5 12.5 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Daxx PF03344.10 KFM02194.1 - 7 5.0 18.8 10 4.4 13.1 1.1 1 0 0 1 1 1 0 Daxx Family Myc_N PF01056.13 KFM02194.1 - 9.1 5.3 12.3 11 5.0 7.8 1.7 2 0 0 2 2 2 0 Myc amino-terminal region TPR_11 PF13414.1 KFM02195.1 - 1.8e-13 49.9 1.8 1.2e-10 40.8 0.2 2.5 2 0 0 2 2 2 2 TPR repeat zf-CCCH PF00642.19 KFM02195.1 - 6e-12 44.9 28.4 3.4e-05 23.3 1.5 4.6 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TPR_1 PF00515.23 KFM02195.1 - 1.7e-10 40.0 1.7 2.8e-06 26.6 0.4 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFM02195.1 - 5.6e-06 26.1 1.6 1.4e-05 24.8 1.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFM02195.1 - 5.7e-06 25.8 3.0 0.00044 19.9 0.3 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFM02195.1 - 2.7e-05 23.6 1.3 0.0033 17.0 0.3 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 KFM02195.1 - 3.4e-05 23.9 0.9 8.8e-05 22.5 0.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KFM02195.1 - 0.0029 17.4 0.2 0.0093 15.7 0.2 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat zf-C2H2_jaz PF12171.3 KFM02195.1 - 0.0029 17.6 5.5 0.0029 17.6 3.8 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding TPR_19 PF14559.1 KFM02195.1 - 0.0077 16.5 0.3 0.016 15.5 0.2 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFM02195.1 - 0.022 15.3 0.1 0.07 13.8 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.1 KFM02195.1 - 0.051 13.7 0.7 0.59 10.4 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFM02195.1 - 0.097 13.3 1.2 0.28 11.9 0.9 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-met PF12874.2 KFM02195.1 - 7.5 6.9 12.6 0.42 10.8 4.1 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type bZIP_2 PF07716.10 KFM02196.1 - 7.5e-16 57.6 11.6 7.5e-16 57.6 8.0 1.6 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 KFM02196.1 - 4e-06 26.6 8.5 7.2e-06 25.8 5.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor Microtub_assoc PF07989.6 KFM02196.1 - 0.03 14.1 0.1 0.068 12.9 0.1 1.6 1 0 0 1 1 1 0 Microtubule associated bZIP_Maf PF03131.12 KFM02196.1 - 0.03 14.6 5.4 0.074 13.3 3.7 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor FlaC_arch PF05377.6 KFM02196.1 - 0.041 13.7 0.2 0.084 12.7 0.1 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) HALZ PF02183.13 KFM02196.1 - 0.051 13.3 0.1 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper BTG PF07742.7 KFM02197.1 - 2.1e-40 136.9 0.0 3e-40 136.4 0.0 1.2 1 0 0 1 1 1 1 BTG family PAM2 PF07145.10 KFM02197.1 - 1.1e-12 46.4 3.9 4.8e-06 25.7 0.0 3.6 4 0 0 4 4 4 2 Ataxin-2 C-terminal region PHF5 PF03660.9 KFM02198.1 - 8.3e-39 131.9 14.0 9.2e-39 131.8 9.7 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.8 KFM02198.1 - 0.036 11.7 3.8 0.039 11.6 2.7 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Aconitase PF00330.15 KFM02199.1 - 1.3e-183 610.7 0.0 2.5e-183 609.8 0.0 1.4 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KFM02199.1 - 3.3e-47 159.8 0.0 7.2e-47 158.7 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain RNA_pol_Rbc25 PF08292.7 KFM02200.1 - 1.7e-45 154.1 0.1 2.7e-45 153.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 KFM02200.1 - 3.2e-20 72.0 0.1 6.3e-20 71.0 0.0 1.5 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 CSD PF00313.17 KFM02201.1 - 2.5e-13 49.5 0.1 3.4e-13 49.1 0.1 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.6 KFM02201.1 - 0.00074 18.9 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease B OB domain PMM PF03332.8 KFM02202.1 - 1.7e-110 367.7 0.1 2e-110 367.5 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 KFM02202.1 - 7.8e-07 28.9 0.0 3.6e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Peptidase_C97 PF05903.9 KFM02203.1 - 2.7e-35 121.3 0.0 3e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain Ku PF02735.11 KFM02204.1 - 1.1e-60 204.5 0.1 2e-60 203.6 0.1 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 KFM02204.1 - 3.4e-57 193.4 0.1 6.1e-57 192.6 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain SAP PF02037.22 KFM02204.1 - 6.4e-10 38.2 0.1 1.3e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 SAP domain Ku_C PF03730.9 KFM02204.1 - 2.9e-08 34.1 0.7 1.1e-07 32.3 0.0 2.3 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm Spc42p PF11544.3 KFM02204.1 - 0.53 10.2 5.9 0.33 10.8 0.6 2.6 2 0 0 2 2 2 0 Spindle pole body component Spc42p Ribosomal_L7Ae PF01248.21 KFM02205.1 - 9.2e-26 89.1 0.1 1.1e-25 88.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 KFM02205.1 - 0.00025 20.8 0.1 0.00029 20.6 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 KFM02205.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 PELOTA RNA binding domain DUF2111 PF09884.4 KFM02206.1 - 0.18 11.6 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2111) ERK-JNK_inhib PF15002.1 KFM02207.1 - 2.1e-51 174.2 0.1 2.3e-51 174.1 0.1 1.0 1 0 0 1 1 1 1 ERK and JNK pathways, inhibitor Med28 PF11594.3 KFM02207.1 - 0.037 14.2 0.8 0.64 10.2 0.0 2.2 2 0 0 2 2 2 0 Mediator complex subunit 28 HLH PF00010.21 KFM02208.1 - 2.3e-16 59.2 0.7 5.4e-16 58.0 0.5 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain BaffR-Tall_bind PF09256.5 KFM02209.1 - 0.00011 21.6 1.9 0.00027 20.4 1.3 1.6 1 0 0 1 1 1 1 BAFF-R, TALL-1 binding FAM176 PF14851.1 KFM02209.1 - 0.054 13.1 0.0 0.088 12.4 0.0 1.2 1 0 0 1 1 1 0 FAM176 family Cut8_N PF14482.1 KFM02209.1 - 0.061 13.3 0.1 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Cut8 proteasome-binding domain CENP-M PF11111.3 KFM02210.1 - 2.4e-72 241.8 0.0 2.7e-72 241.6 0.0 1.0 1 0 0 1 1 1 1 Centromere protein M (CENP-M) Septin PF00735.13 KFM02211.1 - 1.4e-115 385.1 1.5 1.7e-115 384.9 1.0 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KFM02211.1 - 2.3e-08 34.0 0.2 4e-08 33.2 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KFM02211.1 - 8.2e-07 28.3 0.5 1.9e-06 27.1 0.3 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 KFM02211.1 - 3e-05 23.2 0.1 5.5e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.22 KFM02211.1 - 5.2e-05 22.7 0.4 0.0051 16.2 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KFM02211.1 - 0.00019 21.2 7.9 0.027 14.2 0.5 3.2 2 2 2 4 4 4 2 Dynamin family FtsK_SpoIIIE PF01580.13 KFM02211.1 - 0.00023 20.7 0.3 0.0016 17.9 0.1 2.0 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_10 PF12846.2 KFM02211.1 - 0.00032 20.2 0.3 0.00035 20.1 0.2 1.5 1 1 0 1 1 1 1 AAA-like domain Miro PF08477.8 KFM02211.1 - 0.00063 20.2 0.9 0.0024 18.3 0.6 2.1 1 1 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 KFM02211.1 - 0.00096 19.4 0.2 0.0034 17.6 0.0 1.8 2 0 0 2 2 2 1 ABC transporter Ras PF00071.17 KFM02211.1 - 0.0035 16.7 0.2 0.011 15.1 0.1 1.9 1 1 0 2 2 2 1 Ras family AAA_16 PF13191.1 KFM02211.1 - 0.0036 17.3 0.0 0.0061 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFM02211.1 - 0.0057 16.7 0.0 0.013 15.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 KFM02211.1 - 0.0067 15.9 0.1 0.54 9.7 0.0 2.9 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 KFM02211.1 - 0.015 14.8 0.1 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_32 PF13654.1 KFM02211.1 - 0.02 13.5 0.0 0.044 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 KFM02211.1 - 0.028 13.8 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 KFM02211.1 - 0.035 12.9 1.1 0.042 12.6 0.1 1.5 2 0 0 2 2 2 0 NB-ARC domain IIGP PF05049.8 KFM02211.1 - 0.037 12.8 0.8 0.073 11.8 0.1 1.7 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) FeoB_N PF02421.13 KFM02211.1 - 0.042 13.1 0.1 0.089 12.0 0.1 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B KAP_NTPase PF07693.9 KFM02211.1 - 0.043 12.8 0.1 0.052 12.5 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain MobB PF03205.9 KFM02211.1 - 0.052 13.2 0.4 0.12 12.1 0.1 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 KFM02211.1 - 0.055 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KFM02211.1 - 0.086 12.7 0.1 0.36 10.6 0.0 2.0 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.8 KFM02211.1 - 0.09 11.6 0.1 0.17 10.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 KFM02211.1 - 0.097 12.8 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF87 PF01935.12 KFM02211.1 - 0.11 12.2 1.1 0.23 11.2 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF87 WWbp PF10349.4 KFM02212.1 - 1.1e-18 68.1 28.3 1.1e-18 68.1 19.6 2.2 1 1 1 2 2 2 1 WW-domain ligand protein GRAM PF02893.15 KFM02212.1 - 1.6e-09 37.1 0.1 2.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 GRAM domain Melibiase PF02065.13 KFM02213.1 - 1.5e-13 50.2 0.0 2.5e-12 46.2 0.0 2.1 1 1 0 2 2 2 1 Melibiase Glyco_hydro_97 PF10566.4 KFM02213.1 - 5.8e-05 22.3 0.0 0.00073 18.7 0.0 2.0 2 0 0 2 2 2 1 Glycoside hydrolase 97 PH PF00169.24 KFM02214.1 - 2.4e-14 53.4 0.0 3.4e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 KFM02214.1 - 1.1e-05 25.3 0.0 1.8e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 KFM02214.1 - 7.2e-05 23.0 0.1 0.01 16.0 0.1 2.3 1 1 1 2 2 2 1 Pleckstrin homology domain AAA_32 PF13654.1 KFM02214.1 - 0.025 13.2 0.0 0.033 12.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain PH_7 PF15408.1 KFM02214.1 - 0.048 13.5 0.0 0.13 12.1 0.0 1.7 1 1 0 1 1 1 0 Pleckstrin homology domain Complex1_LYR PF05347.10 KFM02215.1 - 1.3e-12 47.2 0.0 2e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KFM02215.1 - 8.1e-09 35.5 0.0 1.8e-08 34.4 0.0 1.5 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 KFM02215.1 - 0.00099 19.5 0.1 0.0012 19.2 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like p450 PF00067.17 KFM02216.1 - 7e-125 417.1 0.1 2.4e-124 415.3 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 zf-HC5HC2H PF13771.1 KFM02217.1 - 1.4e-11 44.3 5.6 3.9e-11 42.9 3.9 1.8 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 KFM02217.1 - 1.2e-07 31.6 2.0 3.6e-07 30.1 1.4 1.7 1 0 0 1 1 1 1 PHD-zinc-finger like domain SH2 PF00017.19 KFM02218.1 - 1.7e-06 27.7 0.0 2.2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 SH2 domain Abhydrolase_6 PF12697.2 KFM02219.1 - 1.2e-30 107.0 0.2 1.5e-30 106.7 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFM02219.1 - 8.1e-19 68.0 0.0 1.8e-18 66.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFM02219.1 - 8.3e-12 45.0 0.0 1.7e-11 44.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KFM02219.1 - 1.2e-05 25.0 0.0 2.2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 KFM02219.1 - 0.0033 17.6 0.4 0.029 14.6 0.1 2.2 2 1 0 2 2 2 1 Thioesterase domain Lipase_3 PF01764.20 KFM02219.1 - 0.012 15.1 0.0 0.025 14.1 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 KFM02219.1 - 0.038 13.5 0.0 0.084 12.4 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Esterase PF00756.15 KFM02219.1 - 0.15 11.4 0.1 0.28 10.5 0.0 1.6 1 1 0 1 1 1 0 Putative esterase RRP7 PF12923.2 KFM02220.1 - 9.6e-43 145.3 9.3 1.4e-42 144.8 6.5 1.2 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) Trans_reg_C PF00486.23 KFM02220.1 - 0.022 14.6 1.0 0.35 10.7 0.5 2.3 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal DNA_pol_A PF00476.15 KFM02220.1 - 0.035 12.7 0.5 0.045 12.3 0.3 1.1 1 0 0 1 1 1 0 DNA polymerase family A RRM_1 PF00076.17 KFM02220.1 - 0.14 11.7 0.2 7.7 6.2 0.0 2.7 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phage_GP20 PF06810.6 KFM02220.1 - 0.21 11.0 2.4 0.18 11.1 0.2 1.8 2 0 0 2 2 2 0 Phage minor structural protein GP20 Atg14 PF10186.4 KFM02220.1 - 0.37 9.6 4.1 0.5 9.2 2.8 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 RRM_1 PF00076.17 KFM02221.1 - 3e-10 39.5 0.0 7.7e-10 38.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM02221.1 - 9.3e-09 35.1 0.0 2.3e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM02221.1 - 6.7e-07 29.0 0.1 1.4e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Globin PF00042.17 KFM02223.1 - 1.3e-30 105.9 0.2 2.2e-30 105.2 0.1 1.4 2 0 0 2 2 2 1 Globin DUF3799 PF12684.2 KFM02223.1 - 0.019 14.3 0.4 0.021 14.2 0.3 1.1 1 0 0 1 1 1 0 PDDEXK-like domain of unknown function (DUF3799) IL12 PF03039.9 KFM02223.1 - 0.13 11.3 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Interleukin-12 alpha subunit LUC7 PF03194.10 KFM02224.1 - 3.2e-79 266.0 30.3 3.2e-79 266.0 21.0 2.5 1 1 1 2 2 2 1 LUC7 N_terminus UBN_AB PF14075.1 KFM02226.1 - 1e-82 276.9 4.0 1e-82 276.9 2.7 2.2 2 0 0 2 2 2 1 Ubinuclein conserved middle domain HUN PF08729.5 KFM02226.1 - 1.8e-20 72.5 0.4 4.5e-20 71.2 0.3 1.7 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Proho_convert PF12177.3 KFM02226.1 - 0.029 13.9 0.1 0.068 12.7 0.1 1.6 1 0 0 1 1 1 0 Prohormone convertase enzyme TPR_19 PF14559.1 KFM02227.1 - 6.5e-17 61.6 17.0 0.00043 20.5 0.6 6.5 5 2 2 7 7 6 5 Tetratricopeptide repeat Apc3 PF12895.2 KFM02227.1 - 9.3e-14 51.3 24.4 0.00022 21.2 0.5 6.0 3 2 3 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 KFM02227.1 - 1.2e-09 38.5 11.2 0.018 15.7 0.8 5.2 4 2 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFM02227.1 - 5.6e-09 35.8 10.6 0.55 11.0 0.0 6.8 6 2 2 8 8 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFM02227.1 - 1.1e-07 31.3 26.4 4.6e-07 29.3 0.2 5.3 6 2 1 7 7 5 3 TPR repeat TPR_2 PF07719.12 KFM02227.1 - 3.6e-06 26.4 30.8 0.03 14.2 0.2 8.9 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_6 PF13174.1 KFM02227.1 - 1.2e-05 25.4 14.2 0.2 12.1 0.0 7.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFM02227.1 - 2.3e-05 24.2 12.3 0.00086 19.3 0.0 6.6 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFM02227.1 - 0.00045 19.7 8.7 4.8 7.1 0.0 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFM02227.1 - 0.00063 19.2 20.8 0.015 14.9 0.0 6.2 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFM02227.1 - 0.0009 19.1 21.7 0.39 10.6 0.9 7.2 6 3 1 7 7 7 3 Tetratricopeptide repeat PPR PF01535.15 KFM02227.1 - 0.0013 18.6 0.3 4.2 7.5 0.0 4.4 4 0 0 4 4 4 1 PPR repeat TPR_9 PF13371.1 KFM02227.1 - 0.0015 18.3 5.0 0.043 13.6 0.4 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFM02227.1 - 0.0038 16.9 9.1 3.5 7.6 0.1 5.2 6 0 0 6 6 5 1 Tetratricopeptide repeat PPR_2 PF13041.1 KFM02227.1 - 0.0068 16.3 0.3 15 5.6 0.0 4.0 3 1 1 4 4 3 0 PPR repeat family TPR_4 PF07721.9 KFM02227.1 - 0.0089 16.3 0.0 26 5.6 0.0 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat Glyco_trans_1_3 PF13528.1 KFM02227.1 - 0.013 14.7 0.0 0.026 13.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 1 Fis1_TPR_C PF14853.1 KFM02227.1 - 0.52 10.2 5.8 2.1 8.3 0.2 3.6 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 KFM02227.1 - 2.3 8.2 8.2 39 4.3 0.1 4.8 6 0 0 6 6 5 0 Tetratricopeptide repeat Guanylate_cyc PF00211.15 KFM02228.1 - 3e-64 215.7 0.0 4.9e-64 215.0 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.12 KFM02228.1 - 5.4e-35 120.6 0.0 1.3e-34 119.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase ANF_receptor PF01094.23 KFM02228.1 - 7.3e-33 113.7 0.0 1.1e-32 113.2 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase PF00069.20 KFM02228.1 - 3.9e-27 95.0 0.1 1.1e-26 93.5 0.1 1.7 1 1 0 1 1 1 1 Protein kinase domain Phospholip_B PF04916.8 KFM02229.1 - 2.5e-166 554.0 1.4 3.4e-166 553.6 1.0 1.1 1 0 0 1 1 1 1 Phospholipase B NMDAR2_C PF10565.4 KFM02232.1 - 5.9e-255 848.1 15.8 7.1e-255 847.9 10.9 1.1 1 0 0 1 1 1 1 N-methyl D-aspartate receptor 2B3 C-terminus Lig_chan PF00060.21 KFM02232.1 - 1.2e-34 119.2 0.1 2e-34 118.4 0.1 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.15 KFM02232.1 - 2.4e-27 95.6 0.0 4.1e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.4 KFM02232.1 - 2.5e-20 72.1 0.3 5e-20 71.2 0.2 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site ANF_receptor PF01094.23 KFM02232.1 - 2.1e-07 30.0 0.1 4.2e-07 29.0 0.0 1.5 1 1 0 1 1 1 1 Receptor family ligand binding region PMP22_Claudin PF00822.15 KFM02233.1 - 1.2e-45 155.1 22.3 1.4e-45 154.9 15.5 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFM02233.1 - 8.1e-07 28.8 16.3 8.1e-07 28.8 11.3 2.1 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF998 PF06197.8 KFM02233.1 - 0.0065 15.7 7.3 0.0065 15.7 5.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF998) DUF4064 PF13273.1 KFM02233.1 - 0.03 14.4 18.4 0.13 12.3 6.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF1218 PF06749.7 KFM02233.1 - 0.047 14.1 0.8 0.047 14.1 0.6 3.6 1 1 2 4 4 4 0 Protein of unknown function (DUF1218) Claudin_3 PF06653.6 KFM02233.1 - 0.063 13.0 23.0 0.11 12.2 15.9 1.4 1 1 0 1 1 1 0 Tight junction protein, Claudin-like OCIA PF07051.6 KFM02233.1 - 0.099 12.0 0.6 0.15 11.5 0.4 1.3 1 0 0 1 1 1 0 Ovarian carcinoma immunoreactive antigen (OCIA) Amastin PF07344.6 KFM02233.1 - 0.15 11.6 24.5 0.65 9.5 16.4 2.0 1 1 1 2 2 2 0 Amastin surface glycoprotein 7TMR-DISM_7TM PF07695.6 KFM02233.1 - 0.44 10.1 28.1 2.6 7.6 12.4 2.5 1 1 1 2 2 2 0 7TM diverse intracellular signalling DUF4079 PF13301.1 KFM02233.1 - 0.47 10.4 7.3 1.1 9.2 5.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) DUF1616 PF07760.6 KFM02233.1 - 4.9 6.1 9.1 0.38 9.8 1.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1616) DUF962 PF06127.6 KFM02233.1 - 7.2 6.5 9.2 0.74 9.7 1.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF962) GSG-1 PF07803.6 KFM02234.1 - 5.1e-48 161.5 0.0 1.1e-47 160.5 0.0 1.6 1 0 0 1 1 1 1 GSG1-like protein Claudin_2 PF13903.1 KFM02234.1 - 1.4e-09 37.9 0.4 2.1e-09 37.3 0.3 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 KFM02234.1 - 5.4e-08 32.6 7.5 1.4e-07 31.3 2.0 2.4 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin family Claudin_3 PF06653.6 KFM02234.1 - 0.059 13.0 7.2 0.41 10.3 3.5 2.4 2 1 0 2 2 2 0 Tight junction protein, Claudin-like Clc-like PF07062.7 KFM02234.1 - 0.7 9.0 0.0 0.7 9.0 0.0 3.1 3 1 1 4 4 4 0 Clc-like DUF1700 PF08006.6 KFM02234.1 - 2.1 7.6 5.1 6.1 6.1 3.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1700) PQQ_2 PF13360.1 KFM02235.1 - 6.1e-09 35.6 0.2 0.0014 18.1 0.0 2.5 2 0 0 2 2 2 2 PQQ-like domain FG-GAP PF01839.18 KFM02235.1 - 4.7e-07 29.3 3.6 0.0019 17.7 0.0 2.9 3 0 0 3 3 3 2 FG-GAP repeat VCBS PF13517.1 KFM02235.1 - 2.5e-06 27.7 0.2 0.084 13.2 0.0 3.2 3 0 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.3 KFM02235.1 - 0.045 13.1 0.2 3.5 7.0 0.0 2.4 2 0 0 2 2 2 0 Insecticide toxin TcdB middle/N-terminal region DUF1409 PF07197.7 KFM02236.1 - 0.0094 15.9 0.1 0.025 14.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1409) HxlR PF01638.12 KFM02236.1 - 0.048 13.2 2.3 0.083 12.5 0.4 2.0 2 0 0 2 2 2 0 HxlR-like helix-turn-helix FlaC_arch PF05377.6 KFM02236.1 - 0.088 12.7 0.8 0.18 11.7 0.5 1.6 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) GSCFA PF08885.6 KFM02236.1 - 0.091 12.2 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 GSCFA family TBPIP PF07106.8 KFM02236.1 - 0.1 12.1 0.1 0.19 11.3 0.0 1.5 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HALZ PF02183.13 KFM02236.1 - 0.13 11.9 0.2 0.32 10.7 0.1 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper I_LWEQ PF01608.12 KFM02236.1 - 0.15 12.0 0.1 0.2 11.5 0.1 1.2 1 0 0 1 1 1 0 I/LWEQ domain Uds1 PF15456.1 KFM02236.1 - 2.9 7.8 5.9 35 4.3 4.1 2.1 1 1 0 1 1 1 0 Up-regulated During Septation SOUL PF04832.7 KFM02237.1 - 3.5e-44 150.4 0.0 3.9e-44 150.2 0.0 1.0 1 0 0 1 1 1 1 SOUL heme-binding protein 7tm_3 PF00003.17 KFM02238.1 - 1.9e-32 112.4 29.3 2.4e-32 112.2 20.3 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF1772 PF08592.6 KFM02238.1 - 0.026 14.2 0.3 0.026 14.2 0.2 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF1772) Tmpp129 PF10272.4 KFM02238.1 - 0.23 10.1 3.0 0.35 9.5 2.1 1.4 1 0 0 1 1 1 0 Putative transmembrane protein precursor DUF1345 PF07077.6 KFM02238.1 - 0.44 10.0 12.2 2.9 7.3 1.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1345) GWT1 PF06423.7 KFM02238.1 - 1.2 9.2 13.9 0.5 10.4 4.0 2.4 1 1 0 2 2 2 0 GWT1 7TMR-DISM_7TM PF07695.6 KFM02238.1 - 3 7.4 34.9 7.6 6.1 23.1 2.1 1 1 0 1 1 1 0 7TM diverse intracellular signalling DEAD PF00270.24 KFM02239.1 - 4.4e-46 156.4 0.2 7.1e-46 155.7 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFM02239.1 - 2.2e-28 97.8 0.2 2.2e-27 94.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFM02239.1 - 0.00041 20.2 0.0 0.0016 18.3 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ApoL PF05461.6 KFM02240.1 - 2.3e-20 73.0 1.9 2.7e-20 72.8 0.2 1.7 2 0 0 2 2 2 1 Apolipoprotein L SseC PF04888.7 KFM02240.1 - 2.2e-05 23.9 0.4 0.00051 19.4 0.1 2.0 2 0 0 2 2 2 1 Secretion system effector C (SseC) like family Serum_albumin PF00273.15 KFM02240.1 - 0.011 15.1 0.9 0.023 14.1 0.6 1.4 1 1 0 1 1 1 0 Serum albumin family DUF4231 PF14015.1 KFM02240.1 - 0.04 13.8 0.4 0.077 12.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Prefoldin PF02996.12 KFM02240.1 - 0.17 11.5 1.1 9.2 5.9 0.0 2.5 3 0 0 3 3 3 0 Prefoldin subunit Histone PF00125.19 KFM02241.1 - 4.1e-27 94.1 0.0 5.4e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFM02241.1 - 3.7e-05 23.6 0.0 5.2e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KFM02242.1 - 4.3e-26 90.8 0.1 6e-26 90.3 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFM02242.1 - 1.2e-06 28.4 1.2 2.3e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KFM02242.1 - 0.0028 17.8 0.0 0.0049 17.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF2606 PF10794.4 KFM02242.1 - 0.056 12.8 0.2 0.094 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) Histone PF00125.19 KFM02243.1 - 3.8e-33 113.4 0.4 5.9e-33 112.8 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KFM02243.1 - 0.00022 21.3 0.0 0.00034 20.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KFM02243.1 - 0.011 15.7 0.1 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 KFM02243.1 - 0.014 14.6 0.5 0.022 14.0 0.3 1.5 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Histone PF00125.19 KFM02244.1 - 4.9e-26 90.6 0.1 6.8e-26 90.1 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFM02244.1 - 9.5e-07 28.7 0.5 2.3e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KFM02244.1 - 0.0026 18.0 0.0 0.0049 17.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF2606 PF10794.4 KFM02244.1 - 0.038 13.4 0.2 0.061 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) Histone PF00125.19 KFM02245.1 - 4.9e-26 90.6 0.1 6.8e-26 90.1 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFM02245.1 - 9.5e-07 28.7 0.5 2.3e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KFM02245.1 - 0.0026 18.0 0.0 0.0049 17.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF2606 PF10794.4 KFM02245.1 - 0.038 13.4 0.2 0.061 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) Histone PF00125.19 KFM02246.1 - 4.9e-26 90.6 0.1 6.8e-26 90.1 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFM02246.1 - 9.5e-07 28.7 0.5 2.3e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KFM02246.1 - 0.0026 18.0 0.0 0.0049 17.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF2606 PF10794.4 KFM02246.1 - 0.038 13.4 0.2 0.061 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) Histone PF00125.19 KFM02247.1 - 4.1e-27 94.1 0.0 5.4e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFM02247.1 - 3.7e-05 23.6 0.0 5.2e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KFM02248.1 - 4.1e-27 94.1 0.0 5.4e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFM02248.1 - 3.7e-05 23.6 0.0 5.2e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KFM02250.1 - 5.2e-15 55.3 0.1 6.3e-15 55.0 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KFM02250.1 - 1.4e-05 25.2 0.1 1.8e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 KFM02250.1 - 3.1e-05 23.8 0.2 4.1e-05 23.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 KFM02250.1 - 0.00021 21.2 0.1 0.00034 20.6 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KFM02250.1 - 0.015 15.0 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 KFM02250.1 - 0.017 14.3 0.0 0.017 14.3 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 KFM02250.1 - 0.037 13.8 0.0 0.046 13.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit RVT_1 PF00078.22 KFM02251.1 - 0.041 13.2 0.0 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Histone PF00125.19 KFM02252.1 - 5.2e-15 55.3 0.1 6.3e-15 55.0 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KFM02252.1 - 1.4e-05 25.2 0.1 1.8e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 KFM02252.1 - 3.1e-05 23.8 0.2 4.1e-05 23.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 KFM02252.1 - 0.00021 21.2 0.1 0.00034 20.6 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KFM02252.1 - 0.015 15.0 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 KFM02252.1 - 0.017 14.3 0.0 0.017 14.3 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 KFM02252.1 - 0.037 13.8 0.0 0.046 13.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 KFM02255.1 - 3.3e-15 55.9 0.1 3.9e-15 55.7 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KFM02255.1 - 9.1e-06 25.7 0.1 1.2e-05 25.3 0.1 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 KFM02255.1 - 2.1e-05 24.3 0.2 2.9e-05 23.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 KFM02255.1 - 0.00014 21.8 0.1 0.00023 21.1 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KFM02255.1 - 0.011 15.4 0.1 0.015 15.0 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 KFM02255.1 - 0.012 14.9 0.0 0.012 14.9 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 KFM02255.1 - 0.027 14.2 0.0 0.031 14.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TFIID_20kDa PF03847.8 KFM02255.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.19 KFM02256.1 - 4.9e-26 90.6 0.1 6.8e-26 90.1 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFM02256.1 - 9.7e-07 28.7 0.5 2.3e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KFM02256.1 - 0.0024 18.0 0.0 0.0049 17.1 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF2606 PF10794.4 KFM02256.1 - 0.059 12.8 0.2 0.093 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) Histone PF00125.19 KFM02257.1 - 2.2e-27 94.9 0.0 2.8e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFM02257.1 - 1.1e-05 25.3 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KFM02258.1 - 4.9e-15 55.4 0.1 5.9e-15 55.1 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KFM02258.1 - 1.3e-05 25.3 0.1 1.7e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 KFM02258.1 - 2.9e-05 23.9 0.2 4e-05 23.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 KFM02258.1 - 0.0002 21.3 0.1 0.00032 20.6 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KFM02258.1 - 0.014 15.0 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 KFM02258.1 - 0.016 14.4 0.0 0.016 14.4 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 KFM02258.1 - 0.037 13.8 0.0 0.046 13.4 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 KFM02260.1 - 1.6e-25 89.0 0.1 2.3e-25 88.5 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFM02260.1 - 1e-06 28.6 0.5 2.3e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KFM02260.1 - 0.0031 17.7 0.0 0.0049 17.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF2606 PF10794.4 KFM02260.1 - 0.051 13.0 0.1 0.076 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) Histone PF00125.19 KFM02261.1 - 3.8e-33 113.4 0.4 5.9e-33 112.8 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KFM02261.1 - 0.00022 21.3 0.0 0.00034 20.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KFM02261.1 - 0.011 15.7 0.1 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 KFM02261.1 - 0.014 14.6 0.5 0.022 14.0 0.3 1.5 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Histone PF00125.19 KFM02262.1 - 4.2e-26 90.8 0.1 5.9e-26 90.3 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFM02262.1 - 1.2e-06 28.4 1.2 2.2e-06 27.6 0.0 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KFM02262.1 - 0.0028 17.9 0.0 0.0048 17.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF2606 PF10794.4 KFM02262.1 - 0.059 12.7 0.2 0.092 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) Histone PF00125.19 KFM02264.1 - 0.021 14.9 0.0 0.039 14.0 0.0 1.5 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Histone PF00125.19 KFM02265.1 - 4.9e-26 90.6 0.1 6.8e-26 90.1 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFM02265.1 - 9.5e-07 28.7 0.5 2.3e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KFM02265.1 - 0.0026 18.0 0.0 0.0049 17.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF2606 PF10794.4 KFM02265.1 - 0.038 13.4 0.2 0.061 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) Histone PF00125.19 KFM02267.1 - 5.2e-15 55.3 0.1 6.3e-15 55.0 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KFM02267.1 - 1.4e-05 25.2 0.1 1.8e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 KFM02267.1 - 3.1e-05 23.8 0.2 4.1e-05 23.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 KFM02267.1 - 0.00021 21.2 0.1 0.00034 20.6 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KFM02267.1 - 0.015 15.0 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 KFM02267.1 - 0.017 14.3 0.0 0.017 14.3 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 KFM02267.1 - 0.037 13.8 0.0 0.046 13.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 KFM02268.1 - 5.1e-26 90.6 0.1 6.8e-26 90.1 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFM02268.1 - 1.1e-06 28.5 0.5 2.3e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KFM02268.1 - 0.003 17.8 0.0 0.0049 17.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF2606 PF10794.4 KFM02268.1 - 0.032 13.6 0.2 0.061 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) Histone PF00125.19 KFM02269.1 - 3.3e-23 81.5 0.0 4.2e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFM02269.1 - 0.00079 19.4 0.0 0.0011 19.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Wbp11 PF09429.5 KFM02270.1 - 1.7e-22 79.1 15.0 1.7e-22 79.1 10.4 2.1 2 0 0 2 2 2 1 WW domain binding protein 11 Effector_1 PF04518.7 KFM02270.1 - 0.12 11.2 1.7 0.16 10.9 1.2 1.1 1 0 0 1 1 1 0 Effector from type III secretion system DUF3391 PF11871.3 KFM02270.1 - 0.2 11.8 9.1 0.97 9.6 6.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) TEX12 PF15219.1 KFM02270.1 - 0.86 9.6 4.7 9.6 6.2 0.9 2.3 1 1 1 2 2 2 0 Testis-expressed 12 DUF4533 PF15047.1 KFM02271.1 - 7.9e-85 283.8 6.9 9e-85 283.6 4.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4533) DNA_repr_REX1B PF14966.1 KFM02271.1 - 0.0011 19.2 0.6 0.044 14.1 0.2 2.4 2 0 0 2 2 2 1 DNA repair REX1-B Herpes_UL31 PF02718.9 KFM02271.1 - 0.012 14.3 1.0 0.018 13.7 0.7 1.2 1 0 0 1 1 1 0 Herpesvirus UL31-like protein MobC PF05713.6 KFM02271.1 - 0.51 10.3 2.4 30 4.6 0.0 3.2 3 0 0 3 3 3 0 Bacterial mobilisation protein (MobC) Syntaxin_2 PF14523.1 KFM02271.1 - 1.3 9.0 5.2 7 6.7 0.1 2.5 2 1 0 2 2 2 0 Syntaxin-like protein DUF4533 PF15047.1 KFM02272.1 - 1.1e-15 57.6 0.3 1.3e-15 57.4 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4533) ART PF01129.13 KFM02273.1 - 2.1e-50 170.9 2.6 2.3e-50 170.7 1.8 1.0 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase ADPrib_exo_Tox PF03496.9 KFM02273.1 - 0.00047 19.4 0.0 0.00068 18.8 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosyltransferase exoenzyme SGT1 PF07093.6 KFM02273.1 - 0.038 12.3 0.2 0.041 12.2 0.1 1.1 1 0 0 1 1 1 0 SGT1 protein Gla PF00594.15 KFM02274.1 - 2.5e-09 36.6 0.3 3.4e-09 36.2 0.2 1.2 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain zf-C4_Topoisom PF01396.14 KFM02274.1 - 0.98 8.9 3.6 0.62 9.6 0.9 1.8 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Gla PF00594.15 KFM02275.1 - 1.3e-13 50.3 6.5 1.4e-13 50.3 2.6 1.9 2 0 0 2 2 2 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain Thioredoxin_6 PF13848.1 KFM02276.1 - 2.9e-23 82.6 0.2 3.2e-23 82.5 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin-like domain Rho_GDI PF02115.12 KFM02277.1 - 2.7e-91 304.4 0.3 3.2e-91 304.1 0.2 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor DUF4316 PF14195.1 KFM02277.1 - 0.056 13.5 0.1 0.099 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) PDE6_gamma PF04868.7 KFM02278.1 - 3.6e-48 161.3 1.2 4e-48 161.1 0.8 1.0 1 0 0 1 1 1 1 Retinal cGMP phosphodiesterase, gamma subunit TP1 PF02079.11 KFM02278.1 - 0.21 11.3 1.0 0.28 10.9 0.7 1.2 1 0 0 1 1 1 0 Nuclear transition protein 1 Peptidase_M14 PF00246.19 KFM02279.1 - 2e-31 109.6 0.0 3.2e-31 108.9 0.0 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.9 KFM02279.1 - 0.0018 17.2 0.0 0.0027 16.6 0.0 1.2 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family TM140 PF14985.1 KFM02280.1 - 1.9e-21 76.5 0.2 2.1e-21 76.4 0.2 1.1 1 0 0 1 1 1 1 TM140 protein family RNase_H2-Ydr279 PF09468.5 KFM02282.1 - 2.7e-51 174.5 0.1 3.4e-51 174.2 0.1 1.0 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) FAM124 PF15067.1 KFM02284.1 - 5.4e-113 376.2 0.0 7.2e-113 375.8 0.0 1.2 1 0 0 1 1 1 1 FAM124 family Serpin PF00079.15 KFM02285.1 - 8.4e-89 298.2 0.8 9.6e-89 298.0 0.6 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Propep_M14 PF02244.11 KFM02285.1 - 0.096 12.3 0.0 0.61 9.7 0.0 2.1 2 0 0 2 2 2 0 Carboxypeptidase activation peptide INT_SG_DDX_CT_C PF15300.1 KFM02286.1 - 1.3e-26 91.8 5.1 3.3e-26 90.5 3.5 1.8 1 0 0 1 1 1 1 INTS6/SAGE1/DDX26B/CT45 C-terminus WD40 PF00400.27 KFM02288.1 - 1.2e-32 110.5 10.1 1.2e-10 40.8 1.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat FYVE PF01363.16 KFM02288.1 - 2.7e-15 55.9 8.2 6.2e-15 54.8 5.7 1.6 1 0 0 1 1 1 1 FYVE zinc finger Nucleoporin_N PF08801.6 KFM02288.1 - 8.1e-07 28.1 0.1 0.081 11.6 0.0 3.7 2 1 1 4 4 4 2 Nup133 N terminal like FYVE_2 PF02318.11 KFM02288.1 - 0.065 13.1 4.8 0.15 11.9 3.3 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger DiS_P_DiS PF06750.8 KFM02288.1 - 3.7 7.3 6.4 33 4.3 4.0 2.7 2 1 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain adh_short PF00106.20 KFM02289.1 - 4.4e-20 72.2 0.0 7.9e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFM02289.1 - 2e-10 40.6 0.1 3.8e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFM02289.1 - 1.4e-08 34.4 0.0 1.7e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KFM02289.1 - 3.1e-07 30.4 0.0 5.6e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KFM02289.1 - 2e-06 27.9 1.4 0.00056 19.9 0.1 2.8 2 1 1 3 3 3 2 NADH(P)-binding DUF1776 PF08643.5 KFM02289.1 - 0.0001 21.5 0.1 0.014 14.5 0.0 2.5 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 KFM02289.1 - 0.048 13.4 0.1 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Hydrolase PF00702.21 KFM02290.1 - 1.7e-73 247.5 0.9 3.5e-73 246.5 0.6 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KFM02290.1 - 1.6e-63 210.7 0.1 3.4e-14 52.7 0.0 6.8 6 0 0 6 6 6 6 Heavy-metal-associated domain E1-E2_ATPase PF00122.15 KFM02290.1 - 7.3e-47 159.3 3.9 2.1e-46 157.8 2.7 1.8 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 KFM02290.1 - 1.8e-15 57.6 0.0 4.3e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFM02290.1 - 5.1e-07 29.5 2.4 8.4e-05 22.2 0.2 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 KFM02290.1 - 0.0015 18.3 0.4 0.068 13.0 0.1 3.0 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Toxin_63 PF15541.1 KFM02290.1 - 0.0018 18.2 0.0 0.5 10.3 0.0 2.8 2 0 0 2 2 2 1 Putative toxin 63 Toxin-deaminase PF14424.1 KFM02290.1 - 9.6 6.1 6.4 27 4.7 0.0 3.9 5 0 0 5 5 5 0 The BURPS668_1122 family of deaminases Glycos_transf_1 PF00534.15 KFM02291.1 - 6.2e-29 100.6 0.0 9.2e-29 100.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KFM02291.1 - 9.2e-11 42.0 0.0 6.2e-10 39.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KFM02291.1 - 9.4e-06 25.8 0.0 1.6e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF4491 PF14898.1 KFM02291.1 - 0.045 13.8 0.2 0.15 12.2 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4491) Glyco_transf_4 PF13439.1 KFM02291.1 - 0.062 13.0 0.0 1.8 8.2 0.0 2.5 1 1 0 1 1 1 0 Glycosyltransferase Family 4 Epimerase_2 PF02350.14 KFM02291.1 - 0.17 10.5 0.0 0.45 9.2 0.0 1.6 2 0 0 2 2 2 0 UDP-N-acetylglucosamine 2-epimerase Pkinase PF00069.20 KFM02292.1 - 7.5e-66 221.9 0.1 7.5e-66 221.9 0.1 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM02292.1 - 5.8e-46 156.6 0.1 5.8e-46 156.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM02292.1 - 4.3e-06 25.9 2.2 4.5e-05 22.5 0.0 2.6 3 0 0 3 3 3 1 Kinase-like Pkinase PF00069.20 KFM02293.1 - 4.5e-68 229.2 0.0 8.3e-68 228.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM02293.1 - 2.5e-46 157.8 0.2 4.8e-46 156.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM02293.1 - 5.7e-09 35.3 0.0 1.2e-07 30.9 0.0 2.2 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 KFM02293.1 - 0.016 14.9 0.0 3.4 7.3 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family CKAP2_C PF15297.1 KFM02294.1 - 2.3e-77 260.1 22.3 9.5e-51 172.6 3.8 3.5 2 2 2 4 4 4 2 Cytoskeleton-associated protein 2 C-terminus EAP30 PF04157.11 KFM02295.1 - 6.8e-58 195.4 2.5 9.1e-58 195.0 1.2 1.5 2 0 0 2 2 2 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 KFM02295.1 - 1.2e-07 31.3 0.0 2.6e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 KFM02295.1 - 0.022 14.2 0.0 0.044 13.2 0.0 1.5 1 0 0 1 1 1 0 GRAM domain MA3 PF02847.12 KFM02295.1 - 0.029 14.0 0.9 0.11 12.2 0.1 2.1 2 0 0 2 2 2 0 MA3 domain Glyco_transf_8 PF01501.15 KFM02295.1 - 0.06 12.6 0.1 0.29 10.4 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 8 DUF1448 PF07289.6 KFM02295.1 - 0.068 12.0 0.1 0.22 10.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1448) Fib_alpha PF08702.5 KFM02295.1 - 0.1 12.7 0.5 0.21 11.7 0.4 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4319 PF14203.1 KFM02295.1 - 1.4 8.5 5.2 0.64 9.5 1.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4319) TSP_1 PF00090.14 KFM02296.1 - 4.3e-11 42.7 8.0 4.3e-11 42.7 5.6 2.5 2 0 0 2 2 2 1 Thrombospondin type 1 domain Fibrinogen_C PF00147.13 KFM02297.1 - 1.4e-59 201.6 10.3 1.5e-59 201.4 7.1 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain KASH PF10541.4 KFM02298.1 - 0.01 15.6 1.3 0.012 15.4 0.5 1.5 2 0 0 2 2 2 0 Nuclear envelope localisation domain PTEN_C2 PF10409.4 KFM02299.1 - 2.4e-26 92.0 0.3 4.5e-26 91.1 0.2 1.5 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.15 KFM02299.1 - 1.2e-09 37.7 0.0 3.4e-09 36.3 0.0 1.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Ion_trans PF00520.26 KFM02299.1 - 1.8e-09 37.1 5.3 1.8e-09 37.1 3.7 1.7 2 0 0 2 2 2 1 Ion transport protein Y_phosphatase PF00102.22 KFM02299.1 - 3.8e-06 26.4 0.0 6.7e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KFM02299.1 - 5.3e-05 23.2 0.1 9.7e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 Inositol hexakisphosphate PKD_channel PF08016.7 KFM02299.1 - 0.0038 15.7 4.2 0.0058 15.1 2.9 1.3 1 0 0 1 1 1 1 Polycystin cation channel Y_phosphatase3 PF13350.1 KFM02299.1 - 0.0087 16.3 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Mito_carr PF00153.22 KFM02300.1 - 4.8e-60 199.2 6.9 1.6e-19 69.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Fibrillarin PF01269.12 KFM02300.1 - 0.15 10.9 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin MRP-S31 PF15433.1 KFM02301.1 - 1.6e-69 234.6 6.3 1.7e-69 234.4 4.4 1.0 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 Fork_head PF00250.13 KFM02302.1 - 4.7e-07 29.7 0.4 9.5e-07 28.7 0.3 1.5 1 0 0 1 1 1 1 Fork head domain NdhM PF10664.4 KFM02302.1 - 0.098 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M COG6 PF06419.6 KFM02303.1 - 1.8e-198 660.6 10.5 2e-198 660.4 7.3 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 BLOC1_2 PF10046.4 KFM02303.1 - 0.001 19.1 2.5 0.0039 17.2 1.7 2.0 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cast PF10174.4 KFM02303.1 - 0.0026 15.9 3.4 0.0041 15.2 2.4 1.2 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone DUF972 PF06156.8 KFM02303.1 - 0.041 14.2 1.7 0.18 12.1 1.1 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF2681 PF10883.3 KFM02303.1 - 0.12 12.6 2.8 0.14 12.3 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Nup54 PF13874.1 KFM02303.1 - 0.15 11.6 4.9 0.082 12.5 0.9 2.3 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 IncA PF04156.9 KFM02303.1 - 0.25 10.9 9.9 0.022 14.3 2.8 2.1 2 0 0 2 2 2 0 IncA protein ERM PF00769.14 KFM02303.1 - 0.55 9.7 9.2 0.029 13.9 2.0 1.9 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Syntaxin PF00804.20 KFM02303.1 - 0.97 9.6 6.7 1.5 8.9 2.7 2.6 1 1 1 2 2 2 0 Syntaxin L_HGMIC_fpl PF10242.4 KFM02304.1 - 1.1e-29 103.6 3.2 1.3e-29 103.5 2.2 1.0 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.1 KFM02304.1 - 0.0008 19.1 0.4 0.0008 19.1 0.3 2.1 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction UPF0016 PF01169.14 KFM02304.1 - 0.0086 16.1 1.2 0.0086 16.1 0.9 1.7 2 0 0 2 2 2 1 Uncharacterized protein family UPF0016 NHL PF01436.16 KFM02305.1 - 1.8e-15 55.9 5.3 3.1e-07 30.0 0.1 5.3 5 1 0 5 5 5 3 NHL repeat SGL PF08450.7 KFM02305.1 - 0.0001 21.7 0.2 0.067 12.5 0.0 3.4 3 1 1 4 4 4 2 SMP-30/Gluconolaconase/LRE-like region Tachylectin PF14517.1 KFM02305.1 - 0.028 13.7 0.3 0.071 12.4 0.0 1.7 2 0 0 2 2 2 0 Tachylectin Lactonase PF10282.4 KFM02305.1 - 0.059 12.4 0.2 1.3 8.0 0.0 2.5 2 1 1 3 3 3 0 Lactonase, 7-bladed beta-propeller DUF4476 PF14771.1 KFM02306.1 - 2.8e-26 91.3 0.8 6.3e-22 77.4 0.2 1.8 1 1 1 2 2 2 2 Domain of unknown function (DUF4476) Band_7 PF01145.20 KFM02307.1 - 7.8e-24 84.5 0.5 9.5e-24 84.2 0.4 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 KFM02307.1 - 0.0011 18.5 0.1 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family L27 PF02828.11 KFM02307.1 - 0.031 13.9 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 L27 domain DUF1400 PF07176.6 KFM02307.1 - 0.15 11.9 2.0 0.33 10.8 0.2 2.1 1 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) A2M_comp PF07678.9 KFM02308.1 - 6.2e-71 238.5 2.7 1.1e-70 237.6 1.9 1.5 1 0 0 1 1 1 1 A-macroglobulin complement component A2M PF00207.17 KFM02308.1 - 1.4e-33 114.2 0.3 6.5e-33 112.1 0.1 2.3 2 0 0 2 2 2 1 Alpha-2-macroglobulin family A2M_recep PF07677.9 KFM02308.1 - 4e-25 87.8 0.5 4.4e-23 81.2 0.0 3.3 3 0 0 3 3 3 1 A-macroglobulin receptor A2M_N_2 PF07703.9 KFM02308.1 - 6.4e-25 87.5 0.3 1.3e-23 83.3 0.1 3.1 2 0 0 2 2 2 1 Alpha-2-macroglobulin family N-terminal region NTR PF01759.16 KFM02308.1 - 4.7e-22 77.6 0.1 1.8e-21 75.7 0.1 2.1 1 0 0 1 1 1 1 UNC-6/NTR/C345C module A2M_N PF01835.14 KFM02308.1 - 3.4e-18 65.7 0.1 2.9e-16 59.5 0.0 3.4 3 0 0 3 3 3 1 MG2 domain Thiol-ester_cl PF10569.4 KFM02308.1 - 2.3e-14 52.3 0.0 4.8e-14 51.2 0.0 1.6 1 0 0 1 1 1 1 Alpha-macro-globulin thiol-ester bond-forming region Prenyltrans_2 PF13249.1 KFM02308.1 - 3.3e-10 40.3 0.5 1.8e-05 25.0 0.0 2.9 1 1 1 2 2 2 2 Prenyltransferase-like ANATO PF01821.13 KFM02308.1 - 4.8e-10 39.4 9.5 4.8e-10 39.4 6.6 1.9 2 0 0 2 2 2 1 Anaphylotoxin-like domain Prenyltrans_1 PF13243.1 KFM02308.1 - 0.0003 20.7 0.1 0.037 14.0 0.0 2.9 1 1 1 2 2 2 2 Prenyltransferase-like MG1 PF11974.3 KFM02308.1 - 0.0033 17.9 0.5 0.92 10.0 0.0 4.0 4 0 0 4 4 4 1 Alpha-2-macroglobulin MG1 domain Ion_trans PF00520.26 KFM02311.1 - 1.2e-34 119.3 12.4 1.9e-34 118.6 8.6 1.4 1 0 0 1 1 1 1 Ion transport protein TRP_2 PF08344.6 KFM02311.1 - 1.9e-30 104.5 1.7 5.9e-30 102.9 1.2 1.9 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_2 PF12796.2 KFM02311.1 - 7.5e-13 48.6 0.8 2.8e-07 30.7 0.5 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFM02311.1 - 5e-11 42.8 0.1 0.00011 22.6 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KFM02311.1 - 3.7e-09 35.9 1.7 0.00052 19.6 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 KFM02311.1 - 1e-06 28.3 3.3 0.054 13.7 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 KFM02311.1 - 1.1e-06 28.7 0.1 0.047 13.9 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) PKD_channel PF08016.7 KFM02311.1 - 0.0012 17.4 15.5 0.025 13.0 10.7 2.6 1 1 0 1 1 1 1 Polycystin cation channel Fasciclin PF02469.17 KFM02312.1 - 6.9e-105 346.1 0.2 7.3e-27 93.8 0.4 4.4 4 0 0 4 4 4 4 Fasciclin domain RNase_PH PF01138.16 KFM02313.1 - 2.5e-24 86.0 0.1 4.6e-24 85.2 0.1 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KFM02313.1 - 9.6e-12 44.6 0.0 2e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Glycos_transf_2 PF00535.21 KFM02314.1 - 9.4e-23 80.7 0.0 1.1e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KFM02314.1 - 9.6e-10 38.6 0.0 1.7e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 KFM02314.1 - 1.6e-05 24.1 0.0 2.1e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 MH2 PF03166.9 KFM02315.1 - 1.2e-77 259.8 0.3 1.6e-77 259.4 0.2 1.1 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.11 KFM02315.1 - 1.3e-42 143.9 1.2 2.9e-42 142.8 0.8 1.6 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.4 KFM02315.1 - 2.3e-06 27.3 0.0 4.1e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Interferon-regulatory factor 3 DUF4223 PF13978.1 KFM02315.1 - 0.11 12.2 0.6 0.22 11.2 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4223) MTP18 PF10558.4 KFM02316.1 - 0.048 13.5 0.0 0.066 13.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) Cyclin_N PF00134.18 KFM02317.1 - 2e-47 159.9 0.1 3.1e-47 159.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFM02317.1 - 2.8e-30 104.6 1.9 4.3e-30 104.0 0.3 2.0 2 1 1 3 3 3 1 Cyclin, C-terminal domain Pkinase PF00069.20 KFM02318.1 - 4.4e-74 248.9 0.0 6.4e-74 248.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM02318.1 - 7.4e-34 116.9 0.0 9.8e-34 116.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DCX PF03607.12 KFM02318.1 - 9.9e-22 76.3 0.3 1.5e-19 69.3 0.0 2.6 2 0 0 2 2 2 1 Doublecortin Kinase-like PF14531.1 KFM02318.1 - 0.00023 20.2 0.0 0.00048 19.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFM02318.1 - 0.0012 17.9 0.0 0.0021 17.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KFM02318.1 - 0.033 13.5 0.0 0.06 12.6 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 KFM02318.1 - 0.16 11.2 0.2 0.33 10.2 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Macoilin PF09726.4 KFM02318.1 - 9.3 4.3 7.2 14 3.7 5.0 1.2 1 0 0 1 1 1 0 Transmembrane protein Mab-21 PF03281.9 KFM02319.1 - 1.4e-89 300.1 0.0 2.1e-89 299.5 0.0 1.3 1 0 0 1 1 1 1 Mab-21 protein RVT_1 PF00078.22 KFM02320.1 - 0.059 12.7 0.0 0.1 11.9 0.0 1.4 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Yae1_N PF09811.4 KFM02321.1 - 1e-09 37.7 23.9 0.032 13.7 16.6 2.9 1 1 0 1 1 1 1 Essential protein Yae1, N terminal Rep_fac_C PF08542.6 KFM02322.1 - 6.4e-21 74.1 0.2 3.3e-20 71.8 0.0 2.3 4 0 0 4 4 4 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KFM02322.1 - 4.2e-10 39.5 0.1 9.5e-10 38.3 0.0 1.5 2 0 0 2 2 2 1 DNA polymerase III, delta subunit DNA_pol3_delta PF06144.8 KFM02322.1 - 2e-07 30.7 0.0 4.3e-07 29.5 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 KFM02322.1 - 4.1e-06 27.0 0.0 8.2e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFM02322.1 - 2.4e-05 24.4 0.5 0.00012 22.2 0.1 2.1 1 1 1 2 2 2 1 AAA domain ABC_tran PF00005.22 KFM02322.1 - 0.0096 16.2 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_10 PF12846.2 KFM02322.1 - 0.013 14.9 0.0 0.022 14.2 0.0 1.4 1 1 0 1 1 1 0 AAA-like domain Rad17 PF03215.10 KFM02322.1 - 0.049 12.3 0.1 0.071 11.7 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 KFM02322.1 - 0.066 13.1 0.2 0.17 11.8 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain Sigma54_activ_2 PF14532.1 KFM02322.1 - 0.1 12.6 0.8 0.3 11.1 0.0 2.1 3 0 0 3 3 3 0 Sigma-54 interaction domain START PF01852.14 KFM02324.1 - 5.6e-41 140.1 0.3 9.9e-41 139.3 0.2 1.4 1 0 0 1 1 1 1 START domain RhoGAP PF00620.22 KFM02324.1 - 7.5e-33 113.2 0.8 1.4e-32 112.3 0.5 1.5 1 0 0 1 1 1 1 RhoGAP domain Glyco_hydro_1 PF00232.13 KFM02325.1 - 5.6e-161 535.7 12.2 1.3e-80 270.8 0.2 4.0 2 2 0 2 2 2 2 Glycosyl hydrolase family 1 HEAT_2 PF13646.1 KFM02327.1 - 1.3e-05 25.3 2.3 3.2 8.1 0.0 6.0 5 1 0 5 5 5 2 HEAT repeats HEAT PF02985.17 KFM02327.1 - 8.9e-05 22.2 4.0 11 6.3 0.0 7.1 7 0 0 7 7 7 2 HEAT repeat Cnd1 PF12717.2 KFM02327.1 - 0.79 9.5 19.3 0.33 10.7 1.2 5.8 4 2 2 6 6 6 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 KFM02327.1 - 1.2 9.6 4.8 1.6e+02 2.9 0.0 5.5 7 0 0 7 7 7 0 HEAT-like repeat AAA_33 PF13671.1 KFM02328.1 - 3e-18 66.0 0.0 5.4e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KFM02328.1 - 1.2e-06 27.7 0.0 3.8e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_17 PF13207.1 KFM02328.1 - 8.6e-06 26.5 0.0 2.4e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFM02328.1 - 0.00024 21.4 0.5 0.0019 18.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 KFM02328.1 - 0.00051 19.3 0.1 0.00051 19.3 0.0 2.7 3 1 0 3 3 3 1 Chromatin associated protein KTI12 ABC_tran PF00005.22 KFM02328.1 - 0.0083 16.4 0.2 0.033 14.5 0.0 2.1 2 0 0 2 2 2 1 ABC transporter PA26 PF04636.8 KFM02328.1 - 0.042 12.5 2.5 0.066 11.8 1.7 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) AAA_33 PF13671.1 KFM02330.1 - 4.9e-10 39.4 0.1 5.9e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain BRCA-2_helical PF09169.5 KFM02331.1 - 5.2e-96 319.8 1.1 2.7e-95 317.5 0.1 2.8 3 0 0 3 3 3 1 BRCA2, helical BRCA-2_OB3 PF09104.5 KFM02331.1 - 3e-63 211.8 0.4 3e-63 211.8 0.3 2.1 2 0 0 2 2 2 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 BRCA2 PF00634.13 KFM02331.1 - 5.8e-50 166.1 19.1 2.8e-11 42.4 0.1 7.3 6 0 0 6 6 6 6 BRCA2 repeat BRCA-2_OB1 PF09103.5 KFM02331.1 - 3.4e-42 142.8 0.0 7.9e-42 141.6 0.0 1.7 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 Tower PF09121.5 KFM02331.1 - 1.1e-22 79.6 3.3 3.4e-22 78.1 2.3 1.9 1 0 0 1 1 1 1 Tower zf-3CxxC PF13695.1 KFM02332.1 - 2.2e-17 63.1 18.8 2.2e-17 63.1 13.1 1.5 2 0 0 2 2 2 1 Zinc-binding domain MSA_2 PF00985.12 KFM02332.1 - 0.14 12.2 2.7 0.24 11.5 1.9 1.3 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family Fringe PF02434.11 KFM02334.1 - 4.3e-65 219.4 0.0 3.1e-57 193.6 0.0 2.6 3 0 0 3 3 3 2 Fringe-like Galactosyl_T PF01762.16 KFM02334.1 - 1.7e-06 27.8 0.0 0.26 10.8 0.0 3.2 2 1 1 3 3 3 3 Galactosyltransferase DUF604 PF04646.7 KFM02334.1 - 0.00013 21.2 0.2 0.00032 19.9 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF604 Glyco_transf_21 PF13506.1 KFM02334.1 - 0.17 11.1 0.0 8.9 5.5 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 21 HSP70 PF00012.15 KFM02335.1 - 4.3e-153 510.4 1.2 4.3e-153 510.4 0.8 3.0 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 KFM02335.1 - 0.0021 16.7 0.1 0.17 10.4 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein MAPEG PF01124.13 KFM02336.1 - 6.6e-09 35.4 1.0 7.7e-09 35.2 0.7 1.2 1 0 0 1 1 1 1 MAPEG family Ndr PF03096.9 KFM02336.1 - 0.15 10.5 0.0 0.18 10.2 0.0 1.1 1 0 0 1 1 1 0 Ndr family DUF4650 PF15509.1 KFM02337.1 - 2.4e-165 551.4 24.3 2.4e-165 551.4 16.9 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4650) Peptidase_C98 PF15499.1 KFM02337.1 - 7.9e-132 438.6 10.8 7.9e-132 438.6 7.5 1.8 2 0 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase HMG_box PF00505.14 KFM02338.1 - 4e-42 142.3 12.9 1.7e-27 95.4 0.4 2.8 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.5 KFM02338.1 - 1.1e-41 141.0 13.6 1.7e-26 92.3 5.5 2.7 3 0 0 3 3 3 2 HMG-box domain CobT PF06213.7 KFM02338.1 - 0.0075 15.4 11.9 0.011 14.8 8.2 1.4 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT Lyase_catalyt PF09093.6 KFM02338.1 - 0.011 14.6 2.5 0.011 14.6 1.8 1.6 2 0 0 2 2 2 0 Lyase, catalytic HMG_box_5 PF14887.1 KFM02338.1 - 0.014 15.2 17.2 0.12 12.1 2.4 2.5 2 1 0 2 2 2 0 HMG (high mobility group) box 5 BSP_II PF05432.6 KFM02338.1 - 0.21 10.8 19.2 0.35 10.1 13.3 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Nucleo_P87 PF07267.6 KFM02338.1 - 1.7 7.2 14.9 2.1 6.9 10.3 1.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PBP_sp32 PF07222.7 KFM02338.1 - 4.8 6.2 15.3 9.3 5.3 10.6 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 AAA PF00004.24 KFM02339.1 - 4.5e-40 136.9 0.0 1e-39 135.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 KFM02339.1 - 8.6e-08 31.9 0.2 4.7e-07 29.5 0.0 2.3 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain AAA_33 PF13671.1 KFM02339.1 - 5.4e-06 26.3 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KFM02339.1 - 1.4e-05 24.2 0.0 2.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 KFM02339.1 - 2.4e-05 24.3 0.0 4.3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KFM02339.1 - 0.00025 20.7 0.5 0.0014 18.3 0.2 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 KFM02339.1 - 0.00027 19.8 0.0 0.00044 19.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 KFM02339.1 - 0.00032 21.4 0.2 0.0017 19.1 0.0 2.2 3 1 0 3 3 1 1 AAA domain AAA_22 PF13401.1 KFM02339.1 - 0.00046 20.3 0.4 0.0046 17.0 0.3 2.6 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KFM02339.1 - 0.00061 19.0 0.2 0.0013 17.9 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KFM02339.1 - 0.0016 17.8 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 KFM02339.1 - 0.0025 17.7 0.0 0.007 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KFM02339.1 - 0.0035 16.4 0.3 0.0087 15.1 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 KFM02339.1 - 0.0036 17.0 0.1 0.0084 15.8 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KFM02339.1 - 0.0037 17.2 0.1 0.043 13.7 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 KFM02339.1 - 0.013 14.9 0.3 0.23 10.8 0.2 2.5 1 1 1 2 2 2 0 AAA domain NACHT PF05729.7 KFM02339.1 - 0.013 15.1 0.1 0.068 12.8 0.1 2.0 1 1 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 KFM02339.1 - 0.019 14.9 0.1 0.04 13.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain TPR_8 PF13181.1 KFM02339.1 - 0.026 14.2 3.7 0.11 12.3 0.2 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat KaiC PF06745.8 KFM02339.1 - 0.027 13.5 0.2 2.1 7.4 0.1 2.4 1 1 1 2 2 2 0 KaiC PhoH PF02562.11 KFM02339.1 - 0.03 13.5 0.0 0.05 12.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Guanylate_kin PF00625.16 KFM02339.1 - 0.045 13.1 0.0 0.18 11.2 0.0 1.9 2 0 0 2 2 2 0 Guanylate kinase RNA_helicase PF00910.17 KFM02339.1 - 0.06 13.5 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.1 KFM02339.1 - 0.065 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KFM02339.1 - 0.095 13.0 4.4 0.27 11.5 1.1 3.0 2 1 0 2 2 1 0 AAA domain UPF0079 PF02367.12 KFM02339.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 KFM02339.1 - 0.19 11.2 0.5 0.38 10.3 0.1 1.7 2 0 0 2 2 1 0 AAA domain TPR_2 PF07719.12 KFM02339.1 - 0.56 10.2 1.8 34 4.6 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Rad60-SLD_2 PF13881.1 KFM02340.1 - 5.9e-32 109.8 0.0 6.8e-32 109.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KFM02340.1 - 0.00032 20.0 0.0 0.00055 19.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin family Met_gamma_lyase PF06838.6 KFM02340.1 - 0.059 11.6 0.0 0.076 11.3 0.0 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase DUF2407 PF10302.4 KFM02340.1 - 0.081 13.1 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain AA_permease_2 PF13520.1 KFM02342.1 - 1.5e-55 188.4 24.1 1.5e-55 188.4 16.7 2.4 2 1 0 2 2 2 1 Amino acid permease AA_permease PF00324.16 KFM02342.1 - 1.3e-44 152.3 23.2 1.3e-44 152.3 16.1 2.4 2 1 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.1 KFM02342.1 - 5.9e-25 86.8 9.6 5.9e-25 86.8 6.6 4.0 5 0 0 5 5 5 1 C-terminus of AA_permease NPV_P10 PF05531.7 KFM02343.1 - 0.011 15.9 2.2 0.016 15.4 1.6 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF2313 PF10076.4 KFM02343.1 - 0.034 13.5 0.2 0.039 13.3 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2313) DUF1795 PF08786.6 KFM02343.1 - 0.068 13.0 0.9 0.12 12.2 0.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1795) DUF4600 PF15372.1 KFM02343.1 - 0.074 13.2 10.0 0.087 13.0 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) Rootletin PF15035.1 KFM02343.1 - 0.095 12.6 10.9 0.12 12.3 7.6 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Apolipoprotein PF01442.13 KFM02343.1 - 0.14 11.6 8.5 0.16 11.4 5.9 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF3573 PF12097.3 KFM02343.1 - 0.16 10.5 0.8 0.16 10.5 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Kinetocho_Slk19 PF12709.2 KFM02343.1 - 0.21 11.7 8.9 0.29 11.2 6.1 1.2 1 0 0 1 1 1 0 Central kinetochore-associated Atg14 PF10186.4 KFM02343.1 - 0.25 10.2 8.5 0.29 10.0 5.9 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Sigma54_AID PF00309.15 KFM02343.1 - 0.41 10.1 10.2 0.46 9.9 1.8 2.3 1 1 0 2 2 2 0 Sigma-54 factor, Activator interacting domain (AID) Spc42p PF11544.3 KFM02343.1 - 0.55 10.1 7.1 1.1 9.2 4.9 1.6 1 1 0 1 1 1 0 Spindle pole body component Spc42p DUF2205 PF10224.4 KFM02343.1 - 0.61 9.7 10.7 1.7 8.2 7.3 1.8 1 1 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) DUF4122 PF13498.1 KFM02343.1 - 0.63 9.3 3.5 2.9 7.2 2.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4122) Snapin_Pallidin PF14712.1 KFM02343.1 - 0.88 9.9 9.0 1.2 9.4 6.2 1.2 1 0 0 1 1 1 0 Snapin/Pallidin DUF972 PF06156.8 KFM02343.1 - 1.2 9.5 10.6 2 8.7 7.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF972) GAS PF13851.1 KFM02343.1 - 1.2 8.2 12.6 1.5 7.9 8.7 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding HAP1_N PF04849.8 KFM02343.1 - 1.2 7.9 10.4 1.5 7.6 7.2 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DUF904 PF06005.7 KFM02343.1 - 1.3 9.3 17.6 7.6 6.9 12.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF904) V_ATPase_I PF01496.14 KFM02343.1 - 1.4 6.6 5.3 1.4 6.6 3.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 KFM02343.1 - 1.8 8.1 10.3 2.3 7.7 7.1 1.1 1 0 0 1 1 1 0 IncA protein GrpE PF01025.14 KFM02343.1 - 2.1 7.8 9.7 2.4 7.6 6.7 1.1 1 0 0 1 1 1 0 GrpE DUF3450 PF11932.3 KFM02343.1 - 2.2 7.4 9.4 2.5 7.3 6.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) NYD-SP28_assoc PF14775.1 KFM02343.1 - 2.5 7.8 18.0 0.15 11.7 2.8 3.0 1 1 2 3 3 3 0 Sperm tail C-terminal domain DMPK_coil PF08826.5 KFM02343.1 - 3.5 7.5 12.2 0.45 10.4 2.7 2.5 2 1 1 3 3 3 0 DMPK coiled coil domain like TMF_DNA_bd PF12329.3 KFM02343.1 - 3.5 7.4 15.1 0.47 10.2 6.4 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 KFM02343.1 - 4.2 6.9 12.7 36 3.9 8.8 2.1 1 1 0 1 1 1 0 Septum formation initiator bZIP_1 PF00170.16 KFM02343.1 - 5 7.1 13.1 0.65 10.0 2.5 2.3 1 1 1 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.10 KFM02343.1 - 6.8 6.5 18.6 0.72 9.7 4.0 3.0 2 1 1 3 3 3 0 Basic region leucine zipper MFS_1 PF07690.11 KFM02345.1 - 2.9e-16 59.1 25.1 2.9e-16 59.1 17.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily UMP1 PF05348.6 KFM02346.1 - 2.2e-45 153.7 0.0 2.5e-45 153.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Pkinase_Tyr PF07714.12 KFM02347.1 - 6.8e-104 346.5 0.0 9.5e-104 346.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM02347.1 - 1.1e-46 159.0 0.0 3.3e-32 111.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain I-set PF07679.11 KFM02347.1 - 6e-26 90.1 0.0 3e-17 62.2 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM02347.1 - 6.2e-22 77.5 0.0 1.9e-10 40.7 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 KFM02347.1 - 1.1e-16 61.0 0.2 1.2e-07 32.0 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.20 KFM02347.1 - 1.8e-11 43.9 0.0 0.00012 22.1 0.0 3.0 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.12 KFM02347.1 - 2.2e-10 40.4 0.2 0.00022 21.1 0.0 3.5 2 1 0 2 2 2 2 Immunoglobulin V-set domain Herpes_gE PF02480.11 KFM02347.1 - 0.02 13.1 0.3 3 5.9 0.0 2.9 1 1 2 3 3 3 0 Alphaherpesvirus glycoprotein E C1-set PF07654.10 KFM02347.1 - 0.036 14.0 0.1 1.6 8.8 0.0 2.6 2 0 0 2 2 2 0 Immunoglobulin C1-set domain C2-set_2 PF08205.7 KFM02347.1 - 0.11 12.3 0.1 0.87 9.5 0.0 2.4 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain Pkinase PF00069.20 KFM02348.1 - 0.0016 17.6 0.0 0.0045 16.1 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM02349.1 - 6e-102 340.1 0.0 8.4e-102 339.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM02349.1 - 2.2e-47 161.3 0.0 1.1e-28 100.1 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain I-set PF07679.11 KFM02349.1 - 9.2e-08 31.8 1.2 0.53 10.1 0.0 5.4 5 0 0 5 5 5 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM02349.1 - 0.0042 17.1 11.1 0.02 15.0 0.0 4.9 5 0 0 5 5 5 1 Immunoglobulin domain Na_Ca_ex PF01699.19 KFM02349.1 - 0.026 14.1 0.4 0.057 13.0 0.3 1.5 1 0 0 1 1 1 0 Sodium/calcium exchanger protein CcmD PF04995.9 KFM02349.1 - 0.076 12.7 0.3 3.5 7.4 0.1 2.5 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) APH PF01636.18 KFM02349.1 - 0.1 12.3 0.0 0.23 11.1 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF3489 PF11994.3 KFM02350.1 - 0.057 13.3 0.2 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3489) AUX_IAA PF02309.11 KFM02350.1 - 0.51 10.0 6.4 0.57 9.8 4.4 1.1 1 0 0 1 1 1 0 AUX/IAA family DUF788 PF05620.6 KFM02350.1 - 8.6 6.1 8.2 0.16 11.8 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF788) PDZ PF00595.19 KFM02351.1 - 9.7e-67 221.1 2.2 7.8e-16 58.0 0.0 4.3 4 0 0 4 4 4 4 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM02351.1 - 1.4e-20 72.9 0.1 2.3e-06 27.4 0.0 4.4 4 0 0 4 4 4 4 PDZ domain zf-C3HC4 PF00097.20 KFM02351.1 - 3.6e-08 32.9 6.7 3.6e-08 32.9 4.6 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM02351.1 - 7.1e-08 32.1 6.9 7.1e-08 32.1 4.8 3.2 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFM02351.1 - 2.4e-06 27.4 6.2 2.4e-06 27.4 4.3 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM02351.1 - 8.3e-06 25.4 5.5 8.3e-06 25.4 3.8 2.6 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFM02351.1 - 3.4e-05 23.4 3.1 3.4e-05 23.4 2.2 3.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFM02351.1 - 7.7e-05 22.4 8.1 7.7e-05 22.4 5.6 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KFM02351.1 - 0.00012 21.6 5.3 0.00043 19.9 3.7 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 KFM02351.1 - 0.0049 16.9 6.5 0.014 15.4 3.2 2.8 2 1 0 2 2 2 1 RING-H2 zinc finger eIF3g PF12353.3 KFM02351.1 - 2.5 8.0 6.0 8.6 6.2 2.1 2.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G IF3_N PF05198.11 KFM02352.1 - 3.7e-18 65.2 0.0 1e-17 63.8 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain IF3_C PF00707.17 KFM02352.1 - 3.9e-14 52.1 2.0 5.7e-14 51.6 0.6 1.9 2 0 0 2 2 2 1 Translation initiation factor IF-3, C-terminal domain Ribosomal_L7Ae PF01248.21 KFM02352.1 - 0.025 14.1 0.0 0.94 9.0 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF3993 PF13158.1 KFM02352.1 - 0.05 13.4 1.0 0.16 11.7 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3993) HTH_33 PF13592.1 KFM02352.1 - 0.066 12.7 0.1 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix Ribosomal_L21p PF00829.16 KFM02352.1 - 0.31 11.1 4.3 0.23 11.5 1.4 1.9 1 1 0 1 1 1 0 Ribosomal prokaryotic L21 protein zf-C2H2 PF00096.21 KFM02353.1 - 2.4e-30 103.0 60.4 7.2e-06 26.0 1.4 8.2 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM02353.1 - 1.5e-20 72.4 67.8 3.3e-06 27.1 0.6 9.5 8 1 1 9 9 9 8 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM02353.1 - 4.7e-20 70.3 50.2 0.00036 20.6 0.6 8.2 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM02353.1 - 3.7e-05 23.7 25.5 0.35 11.0 0.0 7.1 7 1 0 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 KFM02353.1 - 0.02 15.0 0.3 0.02 15.0 0.2 7.8 9 1 0 9 9 9 0 C2H2-type zinc-finger domain CHORD PF04968.7 KFM02353.1 - 0.4 10.9 45.3 1.1 9.5 3.1 7.0 3 3 5 8 8 8 0 CHORD zf-Di19 PF05605.7 KFM02353.1 - 0.48 10.5 25.8 0.76 9.9 4.3 4.9 2 1 2 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 KFM02353.1 - 2 8.7 20.9 25 5.2 0.7 6.8 7 0 0 7 7 7 0 Zinc-finger of C2H2 type FYDLN_acid PF09538.5 KFM02353.1 - 9.6 6.8 7.7 9.2 6.9 0.5 3.2 3 1 0 3 3 3 0 Protein of unknown function (FYDLN_acid) Ras PF00071.17 KFM02354.1 - 1.3e-25 89.6 0.0 1.6e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM02354.1 - 2e-10 41.1 0.0 2.9e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein AlkA_N PF06029.6 KFM02354.1 - 0.13 12.3 0.0 0.19 11.7 0.0 1.6 1 1 0 1 1 1 0 AlkA N-terminal domain Ribosomal_L21e PF01157.13 KFM02355.1 - 4.8e-47 157.8 8.5 4.8e-47 157.8 5.9 1.4 2 0 0 2 2 2 1 Ribosomal protein L21e Jiv90 PF14901.1 KFM02355.1 - 0.098 12.6 0.4 10 6.2 0.2 2.2 1 1 1 2 2 2 0 Cleavage inducing molecular chaperone CLP_protease PF00574.18 KFM02355.1 - 0.11 12.1 0.1 0.17 11.5 0.1 1.2 1 0 0 1 1 1 0 Clp protease UCH PF00443.24 KFM02356.1 - 1.5e-70 237.4 3.4 1.7e-70 237.2 2.3 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFM02356.1 - 9.4e-39 133.5 1.5 1.1e-38 133.3 1.1 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 KFM02356.1 - 0.81 8.9 9.8 2.7 7.2 5.1 2.8 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase 7tm_1 PF00001.16 KFM02357.1 - 1.6e-38 132.3 21.3 2e-38 132.0 14.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM02357.1 - 1.4e-05 24.4 12.4 1.4e-05 24.4 8.6 2.0 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM02357.1 - 0.45 9.5 20.5 0.032 13.3 9.7 2.2 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx WH2 PF02205.15 KFM02358.1 - 6.6e-07 28.7 0.1 1.2e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 WH2 motif Pkinase PF00069.20 KFM02359.1 - 1.6e-52 178.2 0.1 2.2e-52 177.8 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM02359.1 - 3.4e-20 72.2 0.0 5.1e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFM02359.1 - 0.009 15.7 0.1 0.015 15.0 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KFM02359.1 - 0.017 14.2 0.1 0.064 12.3 0.0 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KFM02359.1 - 0.027 13.2 0.1 0.7 8.6 0.0 2.1 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase zf-RING_2 PF13639.1 KFM02360.1 - 1.3e-13 50.5 7.6 2.1e-13 49.8 5.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KFM02360.1 - 2.3e-09 37.1 4.4 4.6e-09 36.2 3.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KFM02360.1 - 2.1e-07 30.5 7.8 3.4e-07 29.7 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM02360.1 - 8.6e-07 28.5 4.5 1.3e-06 27.9 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM02360.1 - 5.7e-06 26.2 8.0 9.3e-06 25.5 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFM02360.1 - 9.3e-06 25.3 1.7 2e-05 24.3 1.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 KFM02360.1 - 1.2e-05 24.9 6.4 1.9e-05 24.3 4.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 KFM02360.1 - 0.011 15.2 4.2 0.019 14.5 2.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 KFM02360.1 - 0.13 11.8 2.9 0.25 10.9 2.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 RINGv PF12906.2 KFM02360.1 - 1.2 9.2 5.6 2.8 8.0 3.9 1.7 1 1 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.6 KFM02360.1 - 7 6.7 6.7 14 5.8 4.7 1.5 1 0 0 1 1 1 0 RING-like domain E1-E2_ATPase PF00122.15 KFM02361.1 - 1.5e-22 79.7 0.1 2.7e-22 78.9 0.1 1.3 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 KFM02361.1 - 1.2e-15 58.2 0.3 2.5e-15 57.1 0.2 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFM02361.1 - 2.8e-13 49.6 0.0 1.4e-12 47.4 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 KFM02361.1 - 5.4e-10 40.0 0.1 3.7e-09 37.3 0.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Colicin_im PF03857.8 KFM02361.1 - 0.0024 17.6 0.2 0.0024 17.6 0.2 2.7 2 0 0 2 2 2 1 Colicin immunity protein Hydrolase_3 PF08282.7 KFM02361.1 - 0.0085 15.6 0.6 0.028 14.0 0.2 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4392 PF14336.1 KFM02361.1 - 0.026 13.3 0.3 0.044 12.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) Shisa PF13908.1 KFM02362.1 - 2.4e-07 31.1 2.3 2.4e-07 31.1 1.6 2.1 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator IncA PF04156.9 KFM02362.1 - 0.017 14.7 0.3 0.021 14.4 0.2 1.1 1 0 0 1 1 1 0 IncA protein FAM163 PF15069.1 KFM02362.1 - 0.062 13.8 2.6 0.096 13.2 1.8 1.3 1 1 0 1 1 1 0 FAM163 family DUF342 PF03961.8 KFM02363.1 - 0.01 14.2 6.2 0.051 11.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Tox-ODYAM1 PF15642.1 KFM02363.1 - 0.016 13.8 5.8 0.023 13.3 4.0 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus DUF1664 PF07889.7 KFM02363.1 - 0.62 9.8 8.1 4.3 7.1 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) COG2 PF06148.6 KFM02363.1 - 0.64 9.8 7.7 1 9.2 0.6 2.8 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Exonuc_VII_L PF02601.10 KFM02363.1 - 0.74 8.9 11.1 1.1 8.3 7.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4435 PF14491.1 KFM02363.1 - 2.7 7.7 4.9 2.3 8.0 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4435) Fib_alpha PF08702.5 KFM02363.1 - 5.6 7.0 13.7 6.6 6.8 2.7 2.4 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Myotub-related PF06602.9 KFM02364.1 - 2.6e-138 460.6 0.3 3.9e-138 460.0 0.2 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.15 KFM02364.1 - 0.00062 19.3 0.1 0.028 13.9 0.0 2.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFM02364.1 - 0.0041 17.3 0.1 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 KFM02364.1 - 0.0055 16.0 0.0 0.016 14.5 0.0 1.7 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CENP-Q PF13094.1 KFM02364.1 - 0.0081 16.1 0.4 0.017 15.1 0.3 1.5 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF2353 PF09789.4 KFM02364.1 - 0.011 15.0 0.1 0.017 14.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) WTX PF09422.5 KFM02365.1 - 8.5e-141 470.1 18.0 1.1e-140 469.7 12.5 1.1 1 0 0 1 1 1 1 WTX protein RhoGEF PF00621.15 KFM02368.1 - 2.3e-48 164.4 5.6 2.3e-48 164.4 3.9 1.8 2 0 0 2 2 2 1 RhoGEF domain SH3_9 PF14604.1 KFM02368.1 - 4.3e-13 48.6 0.2 8.5e-13 47.6 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM02368.1 - 2.1e-10 39.8 2.1 4.6e-10 38.7 1.5 1.6 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 KFM02368.1 - 3.1e-10 40.1 0.7 6.8e-10 39.0 0.5 1.5 1 0 0 1 1 1 1 PH domain SH3_2 PF07653.12 KFM02368.1 - 5.6e-08 32.1 0.0 1.4e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PH_5 PF15405.1 KFM02368.1 - 0.0014 18.6 0.6 0.022 14.7 0.1 2.5 1 1 0 2 2 2 1 Pleckstrin homology domain C1q PF00386.16 KFM02369.1 - 1.1e-39 135.2 0.1 1.5e-39 134.9 0.1 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 KFM02369.1 - 2.6e-29 100.5 81.0 1.6e-10 40.3 17.4 3.6 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Peptidase_M3 PF01432.15 KFM02370.1 - 7.2e-146 486.8 0.0 1e-145 486.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 FtsK_SpoIIIE PF01580.13 KFM02370.1 - 0.14 11.6 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family TNFR_c6 PF00020.13 KFM02371.1 - 2.1e-05 24.4 16.3 8.5e-05 22.5 1.2 5.7 5 1 0 6 6 6 2 TNFR/NGFR cysteine-rich region HEPN PF05168.9 KFM02372.1 - 1.3e-09 37.9 0.1 5.7e-09 35.8 0.1 2.2 1 0 0 1 1 1 1 HEPN domain ubiquitin PF00240.18 KFM02372.1 - 5e-07 29.0 0.0 1.9e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family HATPase_c_3 PF13589.1 KFM02372.1 - 2.1e-05 24.1 0.4 5.3 6.7 0.0 5.1 3 3 0 3 3 3 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DnaJ PF00226.26 KFM02372.1 - 0.011 15.4 0.2 0.037 13.7 0.2 1.8 1 0 0 1 1 1 0 DnaJ domain Sarcoglycan_1 PF04790.8 KFM02373.1 - 6e-107 356.7 0.0 6.8e-107 356.5 0.0 1.0 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein DUF2345 PF10106.4 KFM02373.1 - 0.0075 15.8 0.0 0.033 13.7 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2345) Cadherin PF00028.12 KFM02375.1 - 7.6e-83 272.9 2.3 7.2e-17 61.4 0.0 6.5 5 1 1 6 6 6 6 Cadherin domain Cadherin_2 PF08266.7 KFM02375.1 - 4.8e-14 51.6 0.3 1.4e-12 46.9 0.1 3.4 3 0 0 3 3 3 1 Cadherin-like Syndecan PF01034.15 KFM02375.1 - 0.1 12.2 0.0 0.33 10.6 0.0 1.9 1 0 0 1 1 1 0 Syndecan domain Exo_endo_phos PF03372.18 KFM02377.1 - 3.7e-26 92.5 0.0 4.7e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KFM02377.1 - 8.2e-05 22.1 0.0 0.00035 20.1 0.0 2.1 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase Ets PF00178.17 KFM02378.1 - 4.6e-35 119.6 2.6 7.3e-35 118.9 1.8 1.3 1 0 0 1 1 1 1 Ets-domain Elf-1_N PF12310.3 KFM02378.1 - 2.2e-33 114.4 2.9 2.2e-33 114.4 2.0 2.3 2 0 0 2 2 2 1 Transcription factor protein N terminal NARP1 PF12569.3 KFM02380.1 - 4.1e-216 718.7 23.2 4.1e-216 718.7 16.1 2.0 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_14 PF13428.1 KFM02380.1 - 1e-15 56.8 5.6 0.009 16.5 0.0 8.6 6 3 3 9 9 8 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFM02380.1 - 9.8e-15 53.2 23.4 0.0005 19.7 0.1 9.0 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 KFM02380.1 - 1.4e-14 54.2 18.5 0.0041 17.4 0.3 6.6 5 1 0 6 6 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 KFM02380.1 - 3.3e-11 42.6 30.6 1.1e-05 24.9 0.2 8.1 5 2 3 8 8 8 3 TPR repeat TPR_16 PF13432.1 KFM02380.1 - 5.8e-11 42.7 17.1 0.0032 18.0 0.1 6.2 5 1 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 KFM02380.1 - 3.3e-09 35.9 24.1 0.002 17.6 0.1 8.5 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFM02380.1 - 5.3e-09 35.8 17.7 0.029 14.3 0.2 7.2 5 2 3 8 8 8 4 Tetratricopeptide repeat Apc3 PF12895.2 KFM02380.1 - 8.3e-08 32.2 34.3 0.00049 20.1 0.5 7.2 5 2 3 8 8 8 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KFM02380.1 - 7e-06 25.8 7.2 0.18 11.6 0.2 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFM02380.1 - 2e-05 24.0 31.0 0.0037 16.9 0.1 8.6 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_4 PF07721.9 KFM02380.1 - 0.00041 20.5 0.4 4.3 8.0 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFM02380.1 - 0.0012 18.4 16.6 0.21 11.4 0.1 7.3 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFM02380.1 - 0.003 17.8 13.8 6.6 7.4 0.0 7.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_15 PF13429.1 KFM02380.1 - 0.003 16.6 13.7 0.0033 16.5 2.1 4.4 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_3 PF07720.7 KFM02380.1 - 0.028 14.1 2.1 11 5.9 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KFM02380.1 - 0.055 13.3 7.3 20 5.1 0.1 5.1 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.13 KFM02380.1 - 0.11 12.3 0.0 0.11 12.3 0.0 6.0 6 1 1 7 7 5 0 MIT (microtubule interacting and transport) domain TPR_17 PF13431.1 KFM02380.1 - 0.35 11.1 13.1 1.1e+02 3.4 0.0 7.8 9 0 0 9 9 8 0 Tetratricopeptide repeat F-protein PF00469.15 KFM02380.1 - 0.89 8.8 7.3 0.97 8.7 3.7 1.9 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef DUF1674 PF07896.7 KFM02380.1 - 2.2 8.5 5.0 6.2 7.1 3.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1674) U79_P34 PF03064.11 KFM02380.1 - 3.1 7.2 12.0 5.2 6.5 8.3 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 CD20 PF04103.10 KFM02381.1 - 1e-15 57.9 10.6 1.4e-15 57.5 7.4 1.2 1 0 0 1 1 1 1 CD20-like family DUF1772 PF08592.6 KFM02381.1 - 0.013 15.1 3.6 0.041 13.6 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) DUF2919 PF11143.3 KFM02381.1 - 0.68 9.7 3.7 0.39 10.5 1.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2919) O-antigen_lig PF13425.1 KFM02381.1 - 0.87 9.5 5.3 0.14 12.1 0.3 2.1 1 1 1 2 2 2 0 O-antigen ligase like membrane protein TctB PF07331.6 KFM02381.1 - 1.6 8.3 7.6 5.2 6.7 5.3 1.8 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DUF3671 PF12420.3 KFM02381.1 - 1.8 8.5 5.2 0.77 9.7 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function PMP22_Claudin PF00822.15 KFM02381.1 - 1.9 8.1 6.8 0.77 9.3 1.7 2.3 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin family SUR7 PF06687.7 KFM02381.1 - 9.7 5.6 11.7 2.1 7.8 2.1 2.1 1 1 1 2 2 2 0 SUR7/PalI family MORN PF02493.15 KFM02382.1 - 6e-13 47.7 21.9 0.0012 18.3 0.6 6.5 7 0 0 7 7 7 4 MORN repeat SET PF00856.23 KFM02382.1 - 7.3e-08 32.8 0.1 3.5e-07 30.6 0.0 2.0 1 1 0 1 1 1 1 SET domain MORN_2 PF07661.8 KFM02382.1 - 0.0012 18.6 7.5 0.1 12.6 0.0 4.9 6 0 0 6 6 6 2 MORN repeat variant MAPEG PF01124.13 KFM02383.1 - 3e-17 62.4 1.4 3.3e-17 62.2 0.9 1.1 1 0 0 1 1 1 1 MAPEG family DUF2205 PF10224.4 KFM02385.1 - 8.6e-34 114.9 6.9 1e-33 114.7 4.8 1.1 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) IncA PF04156.9 KFM02385.1 - 0.0017 17.9 3.6 0.0018 17.8 2.5 1.1 1 0 0 1 1 1 1 IncA protein Nse5 PF08691.5 KFM02385.1 - 0.0023 16.5 0.3 0.0024 16.4 0.2 1.1 1 0 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 DUF972 PF06156.8 KFM02385.1 - 0.0044 17.3 4.7 0.0046 17.2 2.6 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF972) bZIP_1 PF00170.16 KFM02385.1 - 0.0072 16.2 0.9 0.0072 16.2 0.6 2.0 1 1 1 2 2 2 1 bZIP transcription factor DUF2683 PF10884.3 KFM02385.1 - 0.0086 15.9 0.6 0.011 15.6 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2683) HALZ PF02183.13 KFM02385.1 - 0.0099 15.5 6.6 0.047 13.4 0.4 2.4 1 1 1 2 2 2 1 Homeobox associated leucine zipper DUF3355 PF11835.3 KFM02385.1 - 0.033 13.9 1.1 0.038 13.7 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3355) Syntaxin-6_N PF09177.6 KFM02385.1 - 0.057 13.8 2.5 0.071 13.5 1.6 1.3 1 1 0 1 1 1 0 Syntaxin 6, N-terminal CENP-F_leu_zip PF10473.4 KFM02385.1 - 0.062 13.1 6.8 0.071 12.9 4.7 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 KFM02385.1 - 0.075 12.0 5.7 0.087 11.8 4.0 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Seadorna_VP6 PF07407.6 KFM02385.1 - 0.083 11.6 0.5 0.082 11.6 0.4 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein RINT1_TIP1 PF04437.8 KFM02385.1 - 0.084 11.4 2.0 0.093 11.2 1.4 1.0 1 0 0 1 1 1 0 RINT-1 / TIP-1 family Spectrin PF00435.16 KFM02385.1 - 0.1 12.9 3.6 0.12 12.6 2.5 1.1 1 0 0 1 1 1 0 Spectrin repeat Troponin PF00992.15 KFM02385.1 - 0.13 12.3 3.2 0.15 12.1 2.2 1.2 1 0 0 1 1 1 0 Troponin DUF3450 PF11932.3 KFM02385.1 - 0.13 11.5 4.4 0.15 11.3 3.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DivIC PF04977.10 KFM02385.1 - 0.15 11.5 6.3 0.065 12.7 0.7 2.0 1 1 1 2 2 2 0 Septum formation initiator DUF904 PF06005.7 KFM02385.1 - 0.44 10.8 8.0 0.73 10.1 5.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF904) V_ATPase_I PF01496.14 KFM02385.1 - 0.5 8.1 5.1 0.5 8.1 3.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_2 PF07716.10 KFM02385.1 - 4.6 7.1 7.7 0.97 9.3 0.4 2.6 1 1 1 2 2 2 0 Basic region leucine zipper Calreticulin PF00262.13 KFM02386.1 - 6.4e-154 512.0 17.0 7.3e-154 511.8 11.8 1.0 1 0 0 1 1 1 1 Calreticulin family Glyco_transf_54 PF04666.8 KFM02387.1 - 9.3e-123 408.7 0.5 1.1e-122 408.4 0.3 1.1 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region zf-RING_2 PF13639.1 KFM02388.1 - 1e-13 50.8 6.4 2.1e-13 49.8 4.4 1.6 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 KFM02388.1 - 1.3e-09 37.6 0.1 2.2e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.2 KFM02388.1 - 3.9e-08 33.2 2.1 8.6e-08 32.1 1.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KFM02388.1 - 7.5e-08 31.9 3.6 1.4e-07 31.0 2.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM02388.1 - 1.6e-07 30.8 4.7 3.3e-07 29.8 3.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM02388.1 - 3.1e-07 30.0 4.0 6.2e-07 29.0 2.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFM02388.1 - 1.4e-06 28.2 6.8 1.4e-06 28.2 4.7 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) UPF0233 PF06781.7 KFM02388.1 - 0.005 16.4 0.5 0.012 15.2 0.3 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0233) zf-Apc11 PF12861.2 KFM02388.1 - 0.0092 15.7 2.3 0.018 14.8 1.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Ninjurin PF04923.7 KFM02388.1 - 0.02 14.6 0.6 0.047 13.4 0.4 1.6 1 0 0 1 1 1 0 Ninjurin PspB PF06667.7 KFM02388.1 - 0.036 14.0 0.1 0.065 13.1 0.1 1.4 1 0 0 1 1 1 0 Phage shock protein B PgaD PF13994.1 KFM02388.1 - 0.065 12.7 0.4 0.1 12.0 0.3 1.3 1 0 0 1 1 1 0 PgaD-like protein BatD PF13584.1 KFM02388.1 - 0.087 11.4 0.2 0.12 10.8 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance PHD PF00628.24 KFM02388.1 - 0.45 10.2 8.1 0.68 9.6 2.9 2.5 2 0 0 2 2 2 0 PHD-finger RINGv PF12906.2 KFM02388.1 - 1.1 9.3 7.4 0.37 10.8 2.9 1.9 2 0 0 2 2 2 0 RING-variant domain NOA36 PF06524.7 KFM02389.1 - 1.1e-165 550.4 43.5 1.3e-165 550.2 30.2 1.0 1 0 0 1 1 1 1 NOA36 protein Nucleoplasmin PF03066.10 KFM02389.1 - 0.35 10.3 3.2 0.51 9.8 2.2 1.3 1 0 0 1 1 1 0 Nucleoplasmin IL15 PF02372.10 KFM02390.1 - 3e-43 146.8 13.4 3.9e-43 146.4 9.3 1.1 1 0 0 1 1 1 1 Interleukin 15 DUF1456 PF07308.8 KFM02390.1 - 0.16 12.0 0.9 0.37 10.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) UCH PF00443.24 KFM02392.1 - 2e-45 154.9 1.0 3.2e-45 154.3 0.7 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFM02392.1 - 1.8e-20 73.6 3.5 1.1e-19 71.0 2.4 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PH PF00169.24 KFM02393.1 - 2.3e-16 59.8 0.2 1.1e-15 57.7 0.0 2.2 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 KFM02393.1 - 3e-07 30.6 0.4 1.4e-06 28.4 0.2 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 KFM02393.1 - 0.051 13.4 0.3 0.15 12.0 0.2 1.7 1 1 0 1 1 1 0 PH domain SNF2_N PF00176.18 KFM02394.1 - 2.1e-85 286.1 0.6 4.2e-85 285.1 0.1 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.5 KFM02394.1 - 1.6e-43 147.1 1.6 5.4e-43 145.4 1.1 2.0 1 0 0 1 1 1 1 SLIDE HAND PF09110.6 KFM02394.1 - 1.6e-27 96.1 1.2 1.6e-27 96.1 0.9 2.9 3 0 0 3 3 3 1 HAND Helicase_C PF00271.26 KFM02394.1 - 6.3e-16 58.0 0.0 2.4e-15 56.1 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFM02394.1 - 1.8e-08 34.4 0.0 2.7e-07 30.6 0.0 3.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KFM02394.1 - 6.3e-08 32.2 0.0 1.6e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.26 KFM02394.1 - 0.00026 20.9 0.1 0.79 9.8 0.0 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain DBINO PF13892.1 KFM02394.1 - 0.0012 18.8 4.6 0.0013 18.8 0.1 3.2 2 0 0 2 2 2 1 DNA-binding domain AAA_22 PF13401.1 KFM02394.1 - 0.1 12.7 0.0 2.8 8.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain TPD PF14811.1 KFM02395.1 - 1.5e-53 180.0 0.1 8.1e-53 177.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function TPD sequence-motif Sigma54_DBD PF04552.8 KFM02395.1 - 0.13 11.7 0.1 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54, DNA binding domain ATP_bind_4 PF01902.12 KFM02397.1 - 2.1e-43 148.2 0.0 5.3e-43 146.9 0.0 1.5 1 1 0 1 1 1 1 ATP-binding region ATPgrasp_ST PF14397.1 KFM02397.1 - 0.069 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp zf-C2H2 PF00096.21 KFM02398.1 - 2e-35 119.0 119.1 2.5e-05 24.3 1.4 12.6 12 0 0 12 12 12 11 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM02398.1 - 2.6e-30 103.1 119.7 2.3e-07 30.7 0.9 14.6 15 0 0 15 15 15 11 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM02398.1 - 1.1e-28 97.4 115.0 6.7e-05 22.9 1.0 13.0 13 0 0 13 13 13 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM02398.1 - 3.4e-06 27.0 69.4 0.099 12.8 0.2 12.4 12 0 0 12 12 12 5 Zinc-finger double-stranded RNA-binding BolA PF01722.13 KFM02398.1 - 5.8e-05 22.9 12.8 3.7 7.5 0.0 6.6 5 3 1 6 6 6 3 BolA-like protein zf-C2H2_6 PF13912.1 KFM02398.1 - 0.00025 20.8 84.0 0.31 10.9 1.0 12.9 13 0 0 13 13 13 7 C2H2-type zinc finger zf-met PF12874.2 KFM02398.1 - 0.017 15.2 80.5 0.5 10.6 0.4 12.5 13 0 0 13 13 13 0 Zinc-finger of C2H2 type FYDLN_acid PF09538.5 KFM02398.1 - 1.1 9.8 13.2 72 4.0 0.2 6.5 6 2 0 6 6 6 0 Protein of unknown function (FYDLN_acid) ROS_MUCR PF05443.6 KFM02398.1 - 2.2 8.0 12.2 11 5.7 0.1 4.6 4 1 1 5 5 5 0 ROS/MUCR transcriptional regulator protein AAA_11 PF13086.1 KFM02399.1 - 5.6e-29 101.3 0.0 1.3e-28 100.1 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_12 PF13087.1 KFM02399.1 - 2e-26 92.6 0.0 4.4e-25 88.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KFM02399.1 - 3.5e-10 39.4 0.0 1.2e-09 37.7 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KFM02399.1 - 1.2e-05 24.9 0.0 0.0022 17.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 KFM02399.1 - 0.00016 21.6 0.0 0.00038 20.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KFM02399.1 - 0.00039 19.9 0.0 0.0011 18.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Parvo_NS1 PF01057.12 KFM02399.1 - 0.0014 17.5 0.0 0.0027 16.6 0.0 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 DUF2075 PF09848.4 KFM02399.1 - 0.0018 17.2 0.2 0.017 14.0 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.16 KFM02399.1 - 0.0023 17.3 0.0 0.015 14.5 0.0 2.3 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA PF00004.24 KFM02399.1 - 0.0037 17.4 0.0 0.0087 16.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KFM02399.1 - 0.0055 16.1 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KFM02399.1 - 0.0081 16.3 0.0 0.042 13.9 0.0 2.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 KFM02399.1 - 0.016 14.4 0.0 0.032 13.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein UvrD_C_2 PF13538.1 KFM02399.1 - 0.068 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_16 PF13191.1 KFM02399.1 - 0.091 12.7 0.1 0.82 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.1 KFM02399.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain RecA PF00154.16 KFM02399.1 - 0.15 11.1 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein DUF4088 PF13317.1 KFM02399.1 - 0.16 11.2 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4088) KaiC PF06745.8 KFM02399.1 - 0.16 11.0 0.0 0.33 10.0 0.0 1.4 1 0 0 1 1 1 0 KaiC DUF755 PF05501.6 KFM02399.1 - 0.94 9.5 2.1 2 8.4 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Actin PF00022.14 KFM02400.1 - 2.7e-143 477.1 0.0 3.3e-143 476.8 0.0 1.0 1 0 0 1 1 1 1 Actin Sec3-PIP2_bind PF15277.1 KFM02401.1 - 4.2e-27 93.8 0.1 8.1e-27 92.9 0.1 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Synaptobrevin PF00957.16 KFM02401.1 - 9.2e-06 25.1 0.6 9.2e-06 25.1 0.4 1.8 2 0 0 2 2 2 1 Synaptobrevin KH_1 PF00013.24 KFM02402.1 - 2.5e-32 110.3 5.6 2.5e-16 59.0 0.4 2.7 3 0 0 3 3 3 2 KH domain KH_3 PF13014.1 KFM02402.1 - 1.4e-23 82.0 2.3 4.8e-11 42.0 0.0 3.3 3 0 0 3 3 3 2 KH domain KH_2 PF07650.12 KFM02402.1 - 1.5e-08 34.0 3.7 2.4e-05 23.7 0.1 2.4 2 0 0 2 2 2 2 KH domain KH_4 PF13083.1 KFM02402.1 - 3.8e-07 29.6 1.4 0.0051 16.4 0.0 2.8 3 0 0 3 3 3 2 KH domain dUTPase PF00692.14 KFM02402.1 - 0.042 13.3 0.0 0.41 10.1 0.0 2.2 2 0 0 2 2 2 0 dUTPase KH_5 PF13184.1 KFM02402.1 - 0.11 12.3 0.8 1 9.2 0.1 2.4 2 0 0 2 2 2 0 NusA-like KH domain DUF1830 PF08865.6 KFM02403.1 - 0.04 13.5 0.0 0.044 13.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1830) Fork_head PF00250.13 KFM02404.1 - 1.6e-46 156.2 0.0 1.8e-46 156.0 0.0 1.0 1 0 0 1 1 1 1 Fork head domain Diphtheria_C PF02763.9 KFM02404.1 - 0.025 14.0 0.1 0.03 13.7 0.1 1.1 1 0 0 1 1 1 0 Diphtheria toxin, C domain Pkinase PF00069.20 KFM02406.1 - 2.4e-64 217.0 0.0 3.8e-64 216.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM02406.1 - 8.6e-33 113.4 0.0 1.5e-32 112.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 KFM02406.1 - 2.6e-27 94.3 19.8 9.2e-14 50.9 5.5 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.24 KFM02406.1 - 8.6e-10 38.7 0.0 5.1e-09 36.2 0.0 2.3 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.1 KFM02406.1 - 7.5e-05 21.8 0.0 0.00059 18.8 0.0 2.3 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 KFM02406.1 - 0.00038 19.5 0.0 0.00077 18.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KFM02406.1 - 0.022 13.5 0.1 0.036 12.8 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 KFM02406.1 - 0.12 12.1 0.3 2.1 7.9 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family C1_3 PF07649.7 KFM02406.1 - 0.12 12.4 13.4 1.5 8.8 1.0 2.6 2 0 0 2 2 2 0 C1-like domain ABC1 PF03109.11 KFM02406.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 ABC1 family zf-RING-like PF08746.6 KFM02406.1 - 0.14 12.2 17.5 0.74 9.8 3.3 2.8 2 0 0 2 2 2 0 RING-like domain PHD PF00628.24 KFM02406.1 - 0.31 10.7 17.7 0.85 9.3 3.5 2.5 2 0 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.1 KFM02406.1 - 0.51 10.1 16.1 0.37 10.5 1.8 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FYVE_2 PF02318.11 KFM02406.1 - 0.52 10.2 10.6 2.6 7.9 3.5 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger PHD_2 PF13831.1 KFM02406.1 - 0.61 9.4 10.0 1 8.6 0.4 2.9 2 0 0 2 2 2 0 PHD-finger DZR PF12773.2 KFM02406.1 - 2.7 7.9 12.9 0.11 12.3 0.6 2.5 2 0 0 2 2 2 0 Double zinc ribbon zf-HC5HC2H PF13771.1 KFM02408.1 - 7.6e-20 70.8 3.8 7.6e-20 70.8 2.7 3.8 3 1 0 3 3 3 1 PHD-like zinc-binding domain HECT PF00632.20 KFM02408.1 - 3.1e-14 52.8 0.3 5e-14 52.1 0.2 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-HC5HC2H_2 PF13832.1 KFM02408.1 - 2.5e-07 30.6 3.9 2.5e-07 30.6 2.7 4.0 2 1 1 4 4 4 1 PHD-zinc-finger like domain Sec1 PF00995.18 KFM02409.1 - 3e-143 478.4 0.6 3.4e-143 478.2 0.4 1.0 1 0 0 1 1 1 1 Sec1 family cwf21 PF08312.7 KFM02409.1 - 0.017 14.9 0.0 0.28 11.0 0.0 2.7 3 0 0 3 3 3 0 cwf21 domain VWA PF00092.23 KFM02410.1 - 2.8e-80 268.2 0.4 1.1e-41 142.4 0.1 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain LCCL PF03815.14 KFM02410.1 - 4.4e-22 77.8 0.0 9.7e-22 76.7 0.0 1.6 1 0 0 1 1 1 1 LCCL domain VWA_2 PF13519.1 KFM02410.1 - 5.9e-18 65.5 0.0 4.3e-11 43.2 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_3 PF13768.1 KFM02410.1 - 0.0024 17.5 0.0 0.48 10.1 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain WD40 PF00400.27 KFM02411.1 - 3.4e-46 153.5 9.7 4.5e-10 39.0 0.0 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat Striatin PF08232.7 KFM02411.1 - 7.9e-26 90.9 1.3 7.9e-26 90.9 0.9 2.5 3 0 0 3 3 3 1 Striatin family Nucleoporin_N PF08801.6 KFM02411.1 - 0.00019 20.2 0.2 0.033 12.9 0.1 2.8 2 1 1 3 3 3 2 Nup133 N terminal like Nup160 PF11715.3 KFM02411.1 - 0.002 16.3 0.2 1.5 6.8 0.0 3.0 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Clat_adaptor_s PF01217.15 KFM02412.1 - 5.9e-38 129.7 8.1 6.6e-38 129.6 5.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain HEAT_2 PF13646.1 KFM02413.1 - 1.1e-13 51.2 14.3 0.15 12.3 0.1 8.8 8 1 2 10 10 10 6 HEAT repeats HEAT PF02985.17 KFM02413.1 - 5.9e-11 41.4 37.8 0.0078 16.2 0.5 11.1 10 0 0 10 10 10 6 HEAT repeat Vac14_Fab1_bd PF12755.2 KFM02413.1 - 0.00027 21.2 0.1 0.0092 16.3 0.0 3.4 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KFM02413.1 - 0.00065 20.1 32.4 0.28 11.7 0.1 10.1 10 1 2 12 12 12 4 HEAT-like repeat Tyr_Deacylase PF02580.11 KFM02414.1 - 7e-38 129.8 0.0 7.9e-38 129.6 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase ParA PF10609.4 KFM02415.1 - 1.8e-36 123.8 0.3 5.4e-36 122.3 0.1 1.9 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 KFM02415.1 - 4.5e-14 52.3 0.0 6.7e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KFM02415.1 - 5.4e-09 36.1 0.0 3.9e-07 30.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 KFM02415.1 - 1.2e-07 31.1 0.0 2e-07 30.3 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 KFM02415.1 - 4.2e-05 22.7 0.2 0.00065 18.8 0.2 2.2 2 0 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.13 KFM02415.1 - 0.00021 20.5 0.1 0.0019 17.4 0.0 2.1 2 1 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.1 KFM02415.1 - 0.00071 19.0 0.2 0.0018 17.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KFM02415.1 - 0.0043 16.7 0.3 0.14 11.8 0.3 2.4 2 0 0 2 2 2 1 Part of AAA domain VirC1 PF07015.6 KFM02415.1 - 0.0082 15.2 0.1 0.023 13.8 0.0 1.6 2 0 0 2 2 2 1 VirC1 protein FtsK_SpoIIIE PF01580.13 KFM02415.1 - 0.13 11.7 0.0 0.3 10.5 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 KFM02415.1 - 0.19 10.8 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin RhoGAP PF00620.22 KFM02416.1 - 3.9e-47 159.6 0.8 7.1e-47 158.8 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain Ras PF00071.17 KFM02416.1 - 5.2e-14 51.9 3.9 3.5e-05 23.2 0.2 4.5 4 0 0 4 4 4 4 Ras family FF PF01846.14 KFM02416.1 - 9.5e-14 51.0 17.7 1.4e-09 37.7 0.8 4.5 5 0 0 5 5 5 3 FF domain AAA_22 PF13401.1 KFM02416.1 - 0.0018 18.4 0.3 2.6 8.1 0.1 3.1 2 1 0 2 2 2 2 AAA domain GTP_EFTU PF00009.22 KFM02416.1 - 0.0027 17.1 0.2 0.0084 15.5 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HLH PF00010.21 KFM02417.1 - 1.6e-05 24.4 0.6 2.1e-05 24.1 0.4 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_3 PF08447.6 KFM02418.1 - 4.9e-21 74.6 0.2 4.8e-16 58.6 0.1 2.4 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.1 KFM02418.1 - 3.2e-15 56.0 0.0 1.7e-11 44.0 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS PF00989.19 KFM02418.1 - 4.3e-11 42.5 0.0 1.4e-07 31.3 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.1 KFM02418.1 - 3.1e-07 30.7 0.0 0.0032 17.7 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 KFM02418.1 - 0.00035 20.5 0.0 0.91 9.5 0.0 2.4 2 0 0 2 2 2 2 PAS fold 2OG-FeII_Oxy_3 PF13640.1 KFM02419.1 - 6.1e-13 49.1 0.0 6.7e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KFM02419.1 - 4.6e-06 26.8 0.0 4.8e-06 26.7 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KFM02419.1 - 3.4e-05 23.3 0.1 8.3e-05 22.1 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF3317 PF11779.3 KFM02420.1 - 1.7e-06 27.3 0.2 1.9e-06 27.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) COX14 PF14880.1 KFM02420.1 - 0.11 12.1 1.2 0.11 12.0 0.9 1.0 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Eapp_C PF10238.4 KFM02421.1 - 5.6e-50 168.7 6.5 5.6e-50 168.7 4.5 1.9 2 1 0 2 2 2 1 E2F-associated phosphoprotein Yippee-Mis18 PF03226.9 KFM02421.1 - 0.0094 15.9 5.3 0.027 14.4 3.7 1.8 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly C1_4 PF07975.7 KFM02421.1 - 0.02 14.8 3.0 0.049 13.6 0.3 2.5 2 0 0 2 2 2 0 TFIIH C1-like domain IBR PF01485.16 KFM02421.1 - 0.021 14.6 1.1 0.12 12.3 0.1 2.3 2 0 0 2 2 2 0 IBR domain DUF2489 PF10675.4 KFM02421.1 - 0.17 11.5 4.0 0.099 12.3 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) DUF925 PF06042.6 KFM02421.1 - 2.2 7.8 5.1 91 2.5 3.5 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF925) PX PF00787.19 KFM02422.1 - 1e-15 57.4 0.6 1.3e-13 50.7 0.1 3.2 2 1 1 3 3 3 1 PX domain Vps5 PF09325.5 KFM02422.1 - 1.6e-15 57.0 16.0 2.2e-13 50.0 9.0 2.8 2 1 0 2 2 2 1 Vps5 C terminal like BAR PF03114.13 KFM02422.1 - 1.8e-07 30.8 14.2 0.00016 21.2 7.0 2.9 3 0 0 3 3 3 2 BAR domain DUF1825 PF08855.5 KFM02422.1 - 0.044 13.7 0.5 0.044 13.7 0.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1825) Cofilin_ADF PF00241.15 KFM02423.1 - 4.4e-38 130.0 0.6 5.3e-38 129.7 0.4 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Methyltransf_26 PF13659.1 KFM02424.1 - 4.2e-06 26.7 0.0 6.4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFM02424.1 - 7.7e-06 26.4 0.0 1.6e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 KFM02424.1 - 0.00011 21.4 0.1 0.00017 20.9 0.1 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_23 PF13489.1 KFM02424.1 - 0.00091 18.9 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFM02424.1 - 0.0013 19.1 0.1 0.0038 17.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFM02424.1 - 0.0018 18.7 0.0 0.0036 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFM02424.1 - 0.0065 16.8 0.1 0.014 15.7 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 KFM02424.1 - 0.1 11.9 1.9 1.1 8.4 1.3 2.3 1 1 0 1 1 1 0 Histone methylation protein DOT1 SRP54 PF00448.17 KFM02425.1 - 6.9e-78 260.6 0.7 4.8e-77 257.8 0.1 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 KFM02425.1 - 1.1e-26 93.0 3.2 1.1e-26 93.0 2.3 3.8 2 1 2 4 4 4 1 Signal peptide binding domain SRP54_N PF02881.14 KFM02425.1 - 1.2e-15 57.3 2.4 3.4e-15 55.9 1.7 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 KFM02425.1 - 4.9e-08 32.6 0.5 2.3e-07 30.4 0.2 2.2 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KFM02425.1 - 1.3e-06 28.3 0.0 2.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 KFM02425.1 - 7.7e-06 25.6 0.0 2.6e-05 23.9 0.0 2.0 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B DUF2209 PF09974.4 KFM02425.1 - 1e-05 25.6 0.3 2.5e-05 24.3 0.2 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2209) CbiA PF01656.18 KFM02425.1 - 1.2e-05 24.8 0.0 4.9e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KFM02425.1 - 0.00016 21.6 0.1 0.39 10.6 0.0 3.4 3 1 1 4 4 3 1 AAA domain SRPRB PF09439.5 KFM02425.1 - 0.00019 20.6 0.5 0.54 9.4 0.0 2.7 1 1 0 2 2 2 2 Signal recognition particle receptor beta subunit AAA_17 PF13207.1 KFM02425.1 - 0.00034 21.4 0.0 0.0011 19.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain ArgK PF03308.11 KFM02425.1 - 0.0017 17.2 0.0 0.031 13.0 0.0 2.4 2 0 0 2 2 2 1 ArgK protein MMR_HSR1 PF01926.18 KFM02425.1 - 0.002 18.0 0.3 0.0071 16.3 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KFM02425.1 - 0.0022 18.1 0.5 0.0082 16.2 0.1 2.3 2 1 0 2 2 1 1 AAA domain AAA_10 PF12846.2 KFM02425.1 - 0.0032 16.9 0.0 0.0045 16.4 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain AAA_19 PF13245.1 KFM02425.1 - 0.0039 16.9 0.0 0.0089 15.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KFM02425.1 - 0.0069 15.9 0.1 0.023 14.2 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.1 KFM02425.1 - 0.015 15.6 0.1 0.057 13.7 0.1 2.2 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.15 KFM02425.1 - 0.024 14.3 0.0 0.051 13.2 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase ATP_bind_1 PF03029.12 KFM02425.1 - 0.025 14.0 1.1 0.16 11.4 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein 6PF2K PF01591.13 KFM02425.1 - 0.03 13.4 0.0 0.071 12.1 0.0 1.6 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_16 PF13191.1 KFM02425.1 - 0.036 14.0 0.0 0.12 12.3 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.7 KFM02425.1 - 0.04 13.0 0.0 0.078 12.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.24 KFM02425.1 - 0.046 13.9 1.8 0.45 10.7 0.1 3.2 2 2 1 3 3 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 KFM02425.1 - 0.051 13.0 0.6 1 8.8 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 KFM02425.1 - 0.099 12.5 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KFM02425.1 - 0.15 12.4 0.9 1.5 9.0 0.6 2.6 1 1 0 1 1 1 0 AAA domain FAM177 PF14774.1 KFM02426.1 - 8.3e-30 103.2 3.2 8.3e-30 103.2 0.0 1.9 1 1 1 2 2 2 1 FAM177 family MCPVI PF02993.9 KFM02426.1 - 0.052 13.6 0.4 0.06 13.4 0.3 1.0 1 0 0 1 1 1 0 Minor capsid protein VI DUF904 PF06005.7 KFM02426.1 - 0.055 13.7 5.8 0.078 13.2 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF904) LLC1 PF14945.1 KFM02426.1 - 0.14 12.5 3.1 0.18 12.0 2.1 1.1 1 0 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein EF-hand_7 PF13499.1 KFM02427.1 - 8.5e-11 41.8 6.0 0.0015 18.6 0.1 4.7 3 2 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 KFM02427.1 - 9.1e-06 25.1 4.3 1.3 9.1 0.0 5.3 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 KFM02427.1 - 4.4e-05 22.4 0.1 0.19 11.0 0.0 4.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 KFM02427.1 - 0.0015 18.0 0.1 2.5 7.8 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 KFM02427.1 - 0.028 13.7 0.2 0.24 10.8 0.0 2.7 2 0 0 2 2 2 0 EF hand PPR_2 PF13041.1 KFM02428.1 - 6.6e-10 38.8 1.5 0.018 14.9 0.0 4.2 3 1 1 4 4 4 3 PPR repeat family PPR_3 PF13812.1 KFM02428.1 - 1.6e-08 34.1 0.2 0.018 15.2 0.0 4.0 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR PF01535.15 KFM02428.1 - 1.8e-07 30.6 4.2 0.0063 16.4 0.0 4.7 4 1 0 4 4 4 2 PPR repeat RNase_Zc3h12a PF11977.3 KFM02428.1 - 7e-05 22.6 0.1 0.00023 21.0 0.1 1.8 1 1 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain Rad50_zn_hook PF04423.9 KFM02428.1 - 0.063 12.7 0.1 0.21 11.0 0.1 1.9 2 0 0 2 2 2 0 Rad50 zinc hook motif Proteasome PF00227.21 KFM02429.1 - 5.8e-53 179.0 0.2 6.7e-53 178.8 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Ank PF00023.25 KFM02430.1 - 5e-36 120.7 8.8 2.6e-09 36.4 0.1 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_2 PF12796.2 KFM02430.1 - 2.3e-32 111.2 2.8 2.2e-16 59.9 0.4 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KFM02430.1 - 1.6e-27 92.8 6.2 5.2e-07 29.2 0.0 4.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 KFM02430.1 - 5.5e-27 93.1 8.5 9.9e-11 41.5 0.0 3.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFM02430.1 - 5.6e-21 74.4 1.9 6.5e-09 36.0 0.2 3.9 2 2 2 4 4 4 4 Ankyrin repeats (many copies) DUF3571 PF12095.3 KFM02430.1 - 0.037 14.2 0.1 0.11 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3571) Shigella_OspC PF06128.6 KFM02430.1 - 0.073 12.5 0.0 0.18 11.2 0.0 1.6 2 0 0 2 2 2 0 Shigella flexneri OspC protein Rap_GAP PF02145.10 KFM02431.1 - 4.1e-62 208.9 0.0 7.2e-62 208.1 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP DUF624 PF04854.9 KFM02431.1 - 0.32 10.8 1.9 2 8.3 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function, DUF624 Sds3 PF08598.6 KFM02432.1 - 1.7e-45 155.0 9.0 5.6e-45 153.4 6.2 1.7 1 1 0 1 1 1 1 Sds3-like ING PF12998.2 KFM02432.1 - 0.035 14.3 3.8 0.26 11.5 2.6 2.2 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Borrelia_P83 PF05262.6 KFM02432.1 - 0.18 10.0 5.7 0.26 9.5 4.0 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein AATF-Che1 PF13339.1 KFM02432.1 - 0.53 10.4 5.2 0.33 11.1 0.2 2.2 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor DUF16 PF01519.11 KFM02432.1 - 1.2 9.3 5.8 3.9 7.7 4.0 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF16 Yae1_N PF09811.4 KFM02435.1 - 8.7e-15 53.9 42.7 6e+03 -3.2 29.6 4.1 1 1 0 1 1 1 0 Essential protein Yae1, N terminal GATA PF00320.22 KFM02436.1 - 2.6e-31 106.6 19.7 1.1e-15 56.6 3.8 2.6 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 KFM02436.1 - 1.5e-05 24.2 7.1 0.025 13.8 0.8 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding DUF2387 PF09526.5 KFM02436.1 - 0.029 14.3 6.3 3.4 7.6 0.8 3.3 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) ArfGap PF01412.13 KFM02436.1 - 0.05 13.3 0.4 0.05 13.3 0.3 2.5 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf eIF-5_eIF-2B PF01873.12 KFM02436.1 - 0.14 11.8 5.2 3.7 7.2 0.6 2.5 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Prim_Zn_Ribbon PF08273.7 KFM02436.1 - 0.14 12.2 11.1 0.087 12.9 1.5 2.9 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase DZR PF12773.2 KFM02436.1 - 0.52 10.1 12.2 9.6 6.1 6.5 3.0 1 1 2 3 3 3 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 KFM02436.1 - 1 9.2 13.2 0.64 9.8 2.6 3.0 2 1 1 3 3 3 0 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 KFM02436.1 - 1.8 8.2 11.4 1.7 8.3 0.8 3.0 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.5 KFM02436.1 - 5.1 7.1 8.8 1.8 8.5 0.1 3.5 3 1 0 4 4 4 0 Zinc ribbon domain Elf1 PF05129.8 KFM02436.1 - 6.5 6.5 8.4 7.9 6.2 0.2 2.7 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like PHD PF00628.24 KFM02437.1 - 1.1e-11 44.1 7.3 2.7e-11 42.9 5.0 1.7 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KFM02437.1 - 0.0025 17.1 1.9 0.0025 17.1 1.3 2.0 2 0 0 2 2 2 1 PHD-finger ATP-synt PF00231.14 KFM02438.1 - 1.2e-76 257.8 1.8 1.4e-76 257.5 1.3 1.0 1 0 0 1 1 1 1 ATP synthase ACT_4 PF13291.1 KFM02438.1 - 0.048 14.0 1.6 0.24 11.7 0.2 2.3 2 0 0 2 2 2 0 ACT domain Viral_P18 PF04521.8 KFM02438.1 - 0.14 11.6 1.4 6.3 6.2 0.4 2.4 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein ITI_HC_C PF06668.7 KFM02439.1 - 4.7e-71 238.0 0.2 9.6e-71 237.0 0.1 1.5 1 0 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus VIT PF08487.5 KFM02439.1 - 2.1e-41 140.3 3.0 3.2e-41 139.7 1.1 2.0 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 KFM02439.1 - 2.8e-21 76.0 0.2 5.7e-21 75.0 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 KFM02439.1 - 1.8e-18 66.7 0.0 3e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 KFM02439.1 - 9.4e-16 58.3 0.1 1.6e-15 57.6 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 KFM02439.1 - 0.0001 21.5 0.0 0.00018 20.7 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.4 KFM02439.1 - 0.00014 21.7 0.3 0.0003 20.6 0.2 1.6 1 0 0 1 1 1 1 vWA found in TerF C terminus DUF2828 PF11443.3 KFM02439.1 - 0.0065 14.7 0.0 0.01 14.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) DUF2201 PF09967.4 KFM02439.1 - 0.0076 16.2 0.0 0.025 14.5 0.0 1.9 1 0 0 1 1 1 1 VWA-like domain (DUF2201) MBT PF02820.13 KFM02440.1 - 4.4e-85 279.6 2.4 7.1e-24 83.5 0.0 4.4 4 0 0 4 4 4 4 mbt repeat DUF3588 PF12140.3 KFM02440.1 - 4.9e-43 145.9 0.2 8.7e-43 145.1 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3588) SAM_1 PF00536.25 KFM02440.1 - 5.7e-08 32.8 0.0 1.1e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 KFM02440.1 - 2.7e-05 23.8 0.2 7.7e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain SAM_2 PF07647.12 KFM02440.1 - 0.00029 20.6 0.0 0.00062 19.5 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ste50p-SAM PF09235.5 KFM02440.1 - 0.0035 17.3 0.1 0.01 15.8 0.1 1.8 1 0 0 1 1 1 1 Ste50p, sterile alpha motif Pkinase PF00069.20 KFM02441.1 - 1.1e-46 159.1 0.0 1.9e-46 158.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain C1_1 PF00130.17 KFM02441.1 - 1.1e-31 108.2 22.5 1.2e-16 60.1 4.7 2.9 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_Tyr PF07714.12 KFM02441.1 - 9.6e-27 93.6 0.0 9.6e-27 93.6 0.0 1.9 3 0 0 3 3 3 1 Protein tyrosine kinase PHD PF00628.24 KFM02441.1 - 0.02 14.5 21.3 0.11 12.1 4.5 2.9 2 0 0 2 2 2 0 PHD-finger Kinase-like PF14531.1 KFM02441.1 - 0.03 13.2 0.0 0.67 8.8 0.0 2.2 2 0 0 2 2 2 0 Kinase-like zf-RING-like PF08746.6 KFM02441.1 - 0.067 13.2 21.5 0.085 12.8 5.6 3.0 2 0 0 2 2 2 0 RING-like domain Prok-RING_1 PF14446.1 KFM02441.1 - 0.068 12.9 15.6 0.15 11.8 2.5 3.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD_2 PF13831.1 KFM02441.1 - 0.14 11.4 10.6 1.2 8.5 1.4 2.9 2 0 0 2 2 2 0 PHD-finger APH PF01636.18 KFM02441.1 - 0.15 11.7 0.0 0.35 10.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DZR PF12773.2 KFM02441.1 - 0.34 10.7 19.6 0.043 13.6 2.2 3.2 3 0 0 3 3 3 0 Double zinc ribbon C1_2 PF03107.11 KFM02441.1 - 0.92 9.6 12.7 0.48 10.5 3.5 3.2 2 0 0 2 2 2 0 C1 domain FYVE PF01363.16 KFM02441.1 - 1.2 9.0 16.6 4.2 7.3 3.0 2.6 2 0 0 2 2 2 0 FYVE zinc finger 6PF2K PF01591.13 KFM02442.1 - 3.5e-103 343.4 0.3 5.9e-103 342.7 0.2 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KFM02442.1 - 1.4e-36 125.9 0.1 2.9e-36 124.9 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KFM02442.1 - 3.3e-08 33.5 0.0 6.5e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFM02442.1 - 5.9e-05 23.8 0.1 0.00023 21.9 0.0 2.1 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 KFM02442.1 - 0.00021 20.6 0.0 0.00034 19.9 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 KFM02442.1 - 0.0016 17.5 0.0 0.0047 16.0 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin His_Phos_2 PF00328.17 KFM02442.1 - 0.073 12.3 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) APS_kinase PF01583.15 KFM02442.1 - 0.12 12.0 0.0 0.3 10.7 0.0 1.7 1 1 0 1 1 1 0 Adenylylsulphate kinase DUF421 PF04239.7 KFM02442.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF421) G-patch PF01585.18 KFM02443.1 - 1.5e-12 47.0 1.3 3.8e-12 45.7 0.9 1.7 1 0 0 1 1 1 1 G-patch domain RRM_5 PF13893.1 KFM02443.1 - 7.3e-08 32.1 0.1 1.5e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFM02443.1 - 0.00015 21.3 0.1 0.0003 20.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nucleo_P87 PF07267.6 KFM02443.1 - 5 5.6 5.7 7 5.2 4.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Sushi PF00084.15 KFM02444.1 - 3e-09 37.0 0.6 3.7e-09 36.7 0.4 1.1 1 0 0 1 1 1 1 Sushi domain (SCR repeat) Endonuclease_NS PF01223.18 KFM02445.1 - 5.5e-30 104.5 1.1 6.8e-30 104.2 0.8 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.1 KFM02445.1 - 0.0023 17.9 0.5 0.005 16.8 0.4 1.6 1 1 0 1 1 1 1 DNA/RNA non-specific endonuclease Muskelin_N PF06588.6 KFM02446.1 - 4.6e-89 297.3 0.3 7.3e-89 296.7 0.2 1.3 1 0 0 1 1 1 1 Muskelin N-terminus Kelch_3 PF13415.1 KFM02446.1 - 6.2e-24 83.5 9.1 2.9e-11 43.2 0.0 5.7 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.1 KFM02446.1 - 1.9e-21 75.5 11.8 1.6e-05 24.5 0.2 7.3 8 0 0 8 8 8 5 Galactose oxidase, central domain Kelch_1 PF01344.20 KFM02446.1 - 8.1e-18 63.6 11.8 2.6e-05 23.6 0.2 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 KFM02446.1 - 5.4e-15 54.8 4.7 0.0066 16.5 0.1 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.1 KFM02446.1 - 5.8e-13 48.4 10.3 0.0044 16.9 0.0 6.1 6 1 0 6 6 6 4 Kelch motif F5_F8_type_C PF00754.20 KFM02446.1 - 1.2e-06 28.3 0.0 3.6e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 F5/8 type C domain Kelch_2 PF07646.10 KFM02446.1 - 1.1e-05 24.9 12.3 0.086 12.6 0.1 6.1 6 1 1 7 7 7 2 Kelch motif Sad1_UNC PF07738.8 KFM02446.1 - 0.038 13.7 0.0 0.085 12.6 0.0 1.6 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal CD34_antigen PF06365.7 KFM02447.1 - 2.2e-64 216.8 2.7 3.1e-64 216.3 1.9 1.2 1 0 0 1 1 1 1 CD34/Podocalyxin family IncA PF04156.9 KFM02447.1 - 0.083 12.4 0.0 0.25 10.9 0.0 1.7 2 0 0 2 2 2 0 IncA protein EphA2_TM PF14575.1 KFM02447.1 - 0.13 12.7 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Plexin_cytopl PF08337.7 KFM02449.1 - 9.1e-261 865.8 2.7 1.1e-260 865.5 1.9 1.1 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain TIG PF01833.19 KFM02449.1 - 2.6e-43 145.8 4.8 2.4e-13 49.9 0.1 6.1 6 0 0 6 6 6 4 IPT/TIG domain PSI PF01437.20 KFM02449.1 - 3.6e-23 81.4 58.5 1.3e-10 41.2 10.4 3.6 3 0 0 3 3 3 3 Plexin repeat DUF948 PF06103.6 KFM02449.1 - 0.011 15.5 0.3 0.033 14.0 0.2 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) MTS PF05175.9 KFM02449.1 - 0.012 14.9 0.0 0.026 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain IncA PF04156.9 KFM02449.1 - 0.031 13.8 0.1 0.061 12.9 0.1 1.4 1 0 0 1 1 1 0 IncA protein UPF0104 PF03706.8 KFM02449.1 - 0.44 9.7 0.0 0.69 9.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) Yae1_N PF09811.4 KFM02450.1 - 2e-09 36.8 25.6 0.00011 21.6 10.2 3.1 1 1 1 2 2 2 2 Essential protein Yae1, N terminal Sema PF01403.14 KFM02451.1 - 2.7e-51 174.4 0.0 3.3e-51 174.1 0.0 1.1 1 0 0 1 1 1 1 Sema domain DUF737 PF05300.6 KFM02452.1 - 1.1e-38 133.0 27.6 1.7e-38 132.4 19.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF737) CHCH PF06747.8 KFM02452.1 - 0.00064 19.5 2.9 0.0012 18.7 2.0 1.5 1 0 0 1 1 1 1 CHCH domain DUF3287 PF11690.3 KFM02452.1 - 0.002 18.1 1.6 0.003 17.6 0.2 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF3287) C_GCAxxG_C_C PF09719.5 KFM02452.1 - 0.29 10.9 4.6 0.098 12.4 0.7 2.0 1 1 1 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) DNA_photolyase PF00875.13 KFM02452.1 - 0.3 10.8 6.2 0.44 10.2 4.2 1.5 1 1 0 1 1 1 0 DNA photolyase Sec8_exocyst PF04048.9 KFM02453.1 - 3.2e-34 117.6 5.4 1.1e-33 115.8 2.1 2.2 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 KFM02453.1 - 3.7e-05 22.7 7.4 3.7e-05 22.7 5.1 1.9 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) COG5 PF10392.4 KFM02453.1 - 0.0013 18.6 2.4 0.0013 18.6 1.7 3.3 2 1 2 4 4 4 1 Golgi transport complex subunit 5 Dor1 PF04124.7 KFM02453.1 - 0.0091 14.4 11.3 0.012 14.1 4.7 2.0 2 0 0 2 2 2 1 Dor1-like family PEP-utilisers_N PF05524.8 KFM02453.1 - 0.052 13.3 0.4 0.18 11.6 0.1 2.0 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Ead_Ea22 PF13935.1 KFM02453.1 - 0.16 12.3 3.8 0.57 10.5 0.6 2.8 2 1 1 3 3 3 0 Ead/Ea22-like protein DASH_Duo1 PF08651.5 KFM02453.1 - 0.21 11.2 7.9 1.5 8.4 0.4 2.9 3 0 0 3 3 3 0 DASH complex subunit Duo1 Vps51 PF08700.6 KFM02453.1 - 0.8 9.5 8.6 2.6 7.9 0.9 2.9 3 0 0 3 3 3 0 Vps51/Vps67 Nsp1_C PF05064.8 KFM02453.1 - 1.5 8.4 6.6 13 5.4 0.2 3.3 3 0 0 3 3 3 0 Nsp1-like C-terminal region DUF2451 PF10474.4 KFM02454.1 - 0.0024 17.6 0.7 0.015 15.0 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Guanylate_kin PF00625.16 KFM02455.1 - 7.7e-27 93.9 0.0 1.6e-26 92.8 0.0 1.5 1 0 0 1 1 1 1 Guanylate kinase LRR_4 PF12799.2 KFM02455.1 - 2.6e-23 81.1 44.8 1.8e-08 33.8 3.1 6.0 5 1 2 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM02455.1 - 2.5e-18 65.5 38.5 1.8e-06 27.5 2.1 5.3 1 1 5 6 6 6 6 Leucine rich repeat LRR_9 PF14580.1 KFM02455.1 - 2.3e-14 53.3 7.2 3e-11 43.1 2.1 2.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.28 KFM02455.1 - 9.9e-07 27.9 39.0 0.45 10.7 0.3 9.5 10 1 0 10 10 10 5 Leucine Rich Repeat LRR_7 PF13504.1 KFM02455.1 - 8.2e-06 25.2 25.3 0.67 10.3 0.1 8.9 8 1 1 9 9 9 3 Leucine rich repeat LRR_6 PF13516.1 KFM02455.1 - 1.1e-05 24.9 32.4 0.078 13.0 0.2 8.9 8 1 2 10 10 10 3 Leucine Rich repeat UAA PF08449.6 KFM02456.1 - 2.7e-96 322.0 21.5 3.2e-96 321.8 14.9 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 KFM02456.1 - 5.4e-06 26.1 13.5 5.4e-06 26.1 9.4 2.7 2 1 1 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 KFM02456.1 - 0.23 11.5 29.6 0.021 14.8 6.6 3.1 3 1 0 3 3 3 0 EamA-like transporter family Orbi_NS3 PF01616.11 KFM02456.1 - 1.3 7.9 5.7 0.9 8.4 0.2 2.3 2 1 0 2 2 2 0 Orbivirus NS3 UCN2 PF11613.3 KFM02457.1 - 4.4e-23 80.9 4.8 1.1e-22 79.6 3.3 1.7 1 0 0 1 1 1 1 Agonist of corticotropin releasing factor R2, Urocortin-2 Nop53 PF07767.6 KFM02457.1 - 0.041 12.8 2.9 0.045 12.7 2.0 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Tad_C PF09977.4 KFM02457.1 - 0.077 14.0 0.0 0.093 13.7 0.0 1.4 1 1 0 1 1 1 0 Putative Tad-like Flp pilus-assembly LRR_8 PF13855.1 KFM02458.1 - 4.4e-36 122.4 32.2 6.2e-10 38.6 0.6 4.4 1 1 4 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 KFM02458.1 - 4.4e-35 118.7 37.7 3.2e-11 42.5 2.4 6.0 3 1 4 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM02458.1 - 2.8e-19 66.1 20.8 0.034 14.1 0.0 8.7 9 0 0 9 9 9 7 Leucine Rich Repeat LRR_7 PF13504.1 KFM02458.1 - 4.1e-11 41.1 16.7 0.4 11.0 0.0 7.8 8 0 0 8 8 8 4 Leucine rich repeat LRR_6 PF13516.1 KFM02458.1 - 1.4e-10 40.1 12.2 0.15 12.2 0.1 6.5 7 0 0 7 7 7 5 Leucine Rich repeat SPATA19 PF15212.1 KFM02458.1 - 0.059 13.4 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Spermatogenesis-associated protein 19, mitochondrial LRR_3 PF07725.7 KFM02458.1 - 0.39 10.5 3.2 18 5.2 0.1 4.2 3 0 0 3 3 3 0 Leucine Rich Repeat TRM13 PF05206.9 KFM02459.1 - 1.2e-91 306.5 1.4 1.7e-91 306.0 0.9 1.2 1 0 0 1 1 1 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.3 KFM02459.1 - 3.6e-14 51.8 2.0 3.6e-14 51.8 1.4 2.6 2 0 0 2 2 2 1 CCCH zinc finger in TRM13 protein zf-U11-48K PF05253.7 KFM02459.1 - 7.1e-11 41.5 2.0 1.5e-10 40.5 1.4 1.6 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.1 KFM02459.1 - 0.0013 18.4 1.9 0.0046 16.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain PBP1_TM PF14812.1 KFM02459.1 - 0.23 11.7 1.6 18 5.7 0.0 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MFS_1 PF07690.11 KFM02460.1 - 1.2e-33 116.2 37.9 3.2e-32 111.6 26.3 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Nuc_sug_transp PF04142.10 KFM02461.1 - 1.4e-102 341.9 12.6 2.6e-102 341.1 8.7 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 KFM02461.1 - 2e-07 30.2 13.3 2.6e-07 29.8 9.2 1.2 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 KFM02461.1 - 3.1e-06 26.8 20.1 3.4e-05 23.5 1.3 3.0 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 KFM02461.1 - 3.3e-06 27.1 23.7 3.7e-06 26.9 1.1 3.2 2 1 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 KFM02461.1 - 0.00016 21.7 3.2 0.00016 21.7 2.2 3.6 1 1 1 3 3 3 1 Multidrug resistance efflux transporter DUF165 PF02592.10 KFM02461.1 - 0.021 14.9 1.9 0.021 14.9 1.3 2.7 3 0 0 3 3 3 0 Uncharacterized ACR, YhhQ family COG1738 DUF4131 PF13567.1 KFM02461.1 - 1 8.7 10.7 3.5 6.9 1.5 3.3 2 1 0 3 3 3 0 Domain of unknown function (DUF4131) hDGE_amylase PF14701.1 KFM02462.1 - 1.5e-168 561.1 0.1 2e-168 560.6 0.1 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 KFM02462.1 - 3.1e-131 437.4 0.0 5e-131 436.8 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 KFM02462.1 - 6.3e-88 294.3 0.0 9.5e-88 293.7 0.0 1.3 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 KFM02462.1 - 9.8e-25 86.2 0.0 2e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 KFM02462.1 - 2e-05 24.1 0.1 0.0002 20.8 0.0 2.2 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Reeler PF02014.11 KFM02463.1 - 1.9e-32 112.2 0.0 2.9e-32 111.6 0.0 1.3 1 0 0 1 1 1 1 Reeler domain DOMON PF03351.12 KFM02463.1 - 6.4e-20 71.3 0.0 1.3e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.11 KFM02463.1 - 0.00055 19.7 10.0 0.0013 18.5 6.9 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Claudin_3 PF06653.6 KFM02463.1 - 0.24 11.1 6.1 0.87 9.2 3.4 2.1 1 1 1 2 2 2 0 Tight junction protein, Claudin-like Paralemmin PF03285.10 KFM02464.1 - 3.3e-25 89.1 18.5 2.1e-12 47.1 10.2 3.1 2 1 0 2 2 2 2 Paralemmin PilJ PF13675.1 KFM02464.1 - 0.0057 16.9 1.3 0.0057 16.9 0.9 1.8 2 0 0 2 2 2 1 Type IV pili methyl-accepting chemotaxis transducer N-term Nup54 PF13874.1 KFM02464.1 - 0.091 12.4 13.4 0.27 10.8 9.1 1.9 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 DUF3573 PF12097.3 KFM02464.1 - 0.59 8.6 1.4 0.94 8.0 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Med22 PF06179.7 KFM02464.1 - 5.3 7.1 13.1 0.22 11.5 1.2 3.3 2 1 1 3 3 3 0 Surfeit locus protein 5 subunit 22 of Mediator complex PAP2 PF01569.16 KFM02465.1 - 2.2e-14 53.2 1.2 3.5e-14 52.5 0.9 1.3 1 0 0 1 1 1 1 PAP2 superfamily PTH2 PF01981.11 KFM02465.1 - 0.25 11.0 1.3 2.6 7.7 0.0 2.8 3 0 0 3 3 3 0 Peptidyl-tRNA hydrolase PTH2 PAP2 PF01569.16 KFM02466.1 - 1.6e-16 60.1 2.5 2.2e-16 59.7 1.7 1.1 1 0 0 1 1 1 1 PAP2 superfamily Cyto_ox_2 PF02322.10 KFM02466.1 - 0.0021 17.2 0.4 0.0032 16.6 0.3 1.2 1 0 0 1 1 1 1 Cytochrome oxidase subunit II SLAC1 PF03595.12 KFM02466.1 - 0.012 14.3 0.5 0.018 13.7 0.3 1.3 1 0 0 1 1 1 0 Voltage-dependent anion channel YjgP_YjgQ PF03739.9 KFM02466.1 - 0.062 12.0 0.2 0.087 11.5 0.1 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Syndecan PF01034.15 KFM02466.1 - 0.14 11.8 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain DUF998 PF06197.8 KFM02466.1 - 0.15 11.3 4.0 0.12 11.6 0.7 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF998) PX PF00787.19 KFM02467.1 - 2.8e-25 88.2 1.2 4.8e-25 87.5 0.5 1.6 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 KFM02467.1 - 4e-06 26.2 6.7 0.00057 19.2 0.2 2.5 2 1 1 3 3 3 2 Vps5 C terminal like BAR PF03114.13 KFM02467.1 - 0.02 14.3 3.7 0.08 12.4 2.6 1.8 1 1 0 1 1 1 0 BAR domain P4Ha_N PF08336.6 KFM02467.1 - 0.5 10.1 3.4 2.7 7.8 0.2 2.6 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DHO_dh PF01180.16 KFM02469.1 - 2.8e-34 118.4 0.0 1.6e-33 115.9 0.0 2.1 2 1 0 2 2 2 1 Dihydroorotate dehydrogenase Fer4_20 PF14691.1 KFM02469.1 - 2.3e-27 94.7 1.2 2.3e-27 94.7 0.8 2.4 2 1 0 2 2 2 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_21 PF14697.1 KFM02469.1 - 2.8e-23 81.5 12.1 2.8e-23 81.5 8.4 3.5 3 1 0 3 3 2 1 4Fe-4S dicluster domain NAD_binding_8 PF13450.1 KFM02469.1 - 2.7e-08 33.6 0.0 8.2e-08 32.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Dus PF01207.12 KFM02469.1 - 3.3e-07 29.4 0.0 4.5e-06 25.7 0.0 2.1 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Pyr_redox_2 PF07992.9 KFM02469.1 - 3.7e-07 30.2 0.0 0.19 11.6 0.0 3.3 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.2 KFM02469.1 - 2.3e-06 27.8 10.2 2.3e-06 27.8 7.0 3.3 3 0 0 3 3 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 KFM02469.1 - 3.1e-06 26.8 10.8 3.1e-06 26.8 7.5 3.1 2 2 1 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 KFM02469.1 - 6.8e-06 26.2 25.9 0.00025 21.2 9.0 2.7 2 0 0 2 2 2 2 4Fe-4S dicluster domain Pyr_redox PF00070.22 KFM02469.1 - 0.00046 20.5 0.1 1.3 9.4 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Fer4_6 PF12837.2 KFM02469.1 - 0.00046 19.9 1.8 0.00046 19.9 1.2 4.2 4 1 0 4 4 3 2 4Fe-4S binding domain Fer4 PF00037.22 KFM02469.1 - 0.0021 17.5 30.3 0.0051 16.3 3.2 5.0 5 0 0 5 5 5 2 4Fe-4S binding domain Pyr_redox_3 PF13738.1 KFM02469.1 - 0.0026 17.8 0.0 3.3 7.7 0.0 2.5 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Fer4_2 PF12797.2 KFM02469.1 - 0.0092 15.8 2.8 0.0092 15.8 1.9 4.3 3 1 1 4 4 3 2 4Fe-4S binding domain Fer4_17 PF13534.1 KFM02469.1 - 0.017 15.4 19.8 0.38 11.1 0.5 3.9 3 1 0 3 3 3 0 4Fe-4S dicluster domain Thi4 PF01946.12 KFM02469.1 - 0.03 13.4 0.0 0.061 12.3 0.0 1.5 1 0 0 1 1 1 0 Thi4 family DAO PF01266.19 KFM02469.1 - 0.04 12.8 0.0 0.14 10.9 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Fer4_15 PF13459.1 KFM02469.1 - 0.051 14.1 9.1 0.83 10.2 0.4 2.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain Shikimate_DH PF01488.15 KFM02469.1 - 0.066 13.3 0.0 14 5.7 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase PcrB PF01884.12 KFM02469.1 - 0.072 12.3 0.1 0.39 9.9 0.0 2.1 3 0 0 3 3 2 0 PcrB family FAD_oxidored PF12831.2 KFM02469.1 - 0.16 11.0 0.1 3.1 6.7 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase NMO PF03060.10 KFM02469.1 - 0.17 11.0 0.5 0.35 9.9 0.3 1.5 1 0 0 1 1 1 0 Nitronate monooxygenase Fer4_8 PF13183.1 KFM02469.1 - 0.57 10.2 29.7 0.032 14.2 2.8 3.7 2 2 1 3 3 3 0 4Fe-4S dicluster domain RRM_5 PF13893.1 KFM02470.1 - 8.1e-47 156.8 3.7 2.6e-13 49.5 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM02470.1 - 1.7e-35 120.8 0.1 4.8e-09 36.0 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFM02470.1 - 6.9e-31 105.6 0.2 4.1e-08 32.7 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RWD PF05773.17 KFM02471.1 - 4.6e-12 45.8 0.1 9.6e-12 44.8 0.1 1.5 1 0 0 1 1 1 1 RWD domain DUF1115 PF06544.7 KFM02471.1 - 2.3e-08 33.7 0.4 4.3e-08 32.9 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Cyto_heme_lyase PF01265.12 KFM02472.1 - 1.2e-90 303.6 4.1 1.7e-90 303.1 2.9 1.2 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase TRAM_LAG1_CLN8 PF03798.11 KFM02473.1 - 1e-40 139.4 15.2 1e-40 139.4 10.5 1.4 2 0 0 2 2 2 1 TLC domain DUF3007 PF11460.3 KFM02473.1 - 0.52 10.4 5.5 0.24 11.4 0.8 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3007) Alg14 PF08660.6 KFM02474.1 - 4.5e-62 209.0 0.0 5.1e-62 208.8 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Calponin PF00402.13 KFM02475.1 - 2.5e-39 132.2 13.0 3.8e-14 51.6 0.8 3.6 3 0 0 3 3 3 3 Calponin family repeat CH PF00307.26 KFM02475.1 - 9.2e-17 61.0 0.0 1.5e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFM02475.1 - 0.025 14.2 0.0 0.046 13.3 0.0 1.5 1 0 0 1 1 1 0 CAMSAP CH domain CDC24 PF06395.6 KFM02475.1 - 0.11 12.5 0.1 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 CDC24 Calponin Choline_transpo PF04515.7 KFM02476.1 - 4.8e-93 311.5 32.8 4.8e-93 311.5 22.8 1.9 3 0 0 3 3 3 1 Plasma-membrane choline transporter DUF4131 PF13567.1 KFM02476.1 - 0.00097 18.5 8.5 0.00097 18.5 5.9 4.5 3 1 3 6 6 6 1 Domain of unknown function (DUF4131) PDR_CDR PF06422.7 KFM02476.1 - 0.037 13.6 2.0 1.9 8.1 0.1 3.1 2 0 0 2 2 2 0 CDR ABC transporter Interfer-bind PF09294.5 KFM02477.1 - 2.3e-21 75.8 1.4 1.4e-20 73.3 0.1 2.1 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.12 KFM02477.1 - 8.7e-20 70.4 0.3 2.2e-19 69.1 0.2 1.6 1 0 0 1 1 1 1 Tissue factor IncA PF04156.9 KFM02477.1 - 0.05 13.1 0.4 0.084 12.4 0.3 1.2 1 0 0 1 1 1 0 IncA protein DUF912 PF06024.7 KFM02477.1 - 0.098 12.7 3.3 0.24 11.4 2.3 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DAP10 PF07213.6 KFM02477.1 - 0.14 11.9 0.3 0.24 11.1 0.2 1.3 1 0 0 1 1 1 0 DAP10 membrane protein TMEM154 PF15102.1 KFM02477.1 - 1.2 8.8 7.6 0.16 11.7 2.3 1.9 2 1 0 2 2 2 0 TMEM154 protein family ABC_membrane_2 PF06472.10 KFM02478.1 - 9.7e-101 336.5 7.7 1.3e-100 336.2 5.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KFM02478.1 - 6e-18 65.4 0.0 1.4e-17 64.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KFM02478.1 - 0.00022 21.3 2.2 0.0048 16.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 KFM02478.1 - 0.00095 19.5 0.0 0.0028 17.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 KFM02478.1 - 0.0016 17.7 0.0 0.24 10.5 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KFM02478.1 - 0.0075 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KFM02478.1 - 0.022 14.7 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 KFM02478.1 - 0.098 11.8 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 KFM02478.1 - 0.12 11.7 0.0 0.29 10.5 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein RhoGAP PF00620.22 KFM02479.1 - 3.7e-50 169.4 0.4 3.7e-50 169.4 0.2 2.4 2 0 0 2 2 2 1 RhoGAP domain C1_1 PF00130.17 KFM02479.1 - 1.8e-06 27.5 9.7 4.5e-06 26.2 6.7 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Steroid_dh PF02544.11 KFM02480.1 - 3.2e-26 91.8 5.7 6e-26 91.0 3.9 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Aldo_ket_red PF00248.16 KFM02481.1 - 4e-07 29.1 0.0 5.9e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Fcf2 PF08698.6 KFM02482.1 - 1.6e-33 114.6 0.2 1.6e-33 114.6 0.1 3.1 4 0 0 4 4 4 1 Fcf2 pre-rRNA processing SH2 PF00017.19 KFM02483.1 - 4.4e-15 55.2 0.3 1.1e-14 53.9 0.0 1.9 2 0 0 2 2 2 1 SH2 domain RasGEF PF00617.14 KFM02483.1 - 8.8e-13 48.3 0.1 1.7e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain FCH PF00611.18 KFM02484.1 - 1.8e-18 66.5 0.0 1.8e-18 66.5 0.0 3.6 3 2 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 KFM02484.1 - 4.3e-13 48.4 0.1 9.2e-13 47.3 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFM02484.1 - 4.8e-12 45.2 0.0 1.3e-11 43.9 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFM02484.1 - 7.1e-07 28.6 0.1 1.5e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 KFM02484.1 - 4.5e-05 23.5 0.1 8.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain Lzipper-MIP1 PF14389.1 KFM02484.1 - 0.00098 19.1 1.5 0.00098 19.1 1.1 2.0 2 1 0 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 HR1 PF02185.11 KFM02484.1 - 0.012 15.3 1.1 0.012 15.3 0.8 3.9 4 0 0 4 4 4 0 Hr1 repeat COG5 PF10392.4 KFM02484.1 - 0.056 13.3 0.2 0.056 13.3 0.2 2.4 2 1 1 3 3 3 0 Golgi transport complex subunit 5 DnaJ PF00226.26 KFM02484.1 - 0.28 10.9 4.4 4 7.2 0.0 2.6 2 0 0 2 2 2 0 DnaJ domain DUF342 PF03961.8 KFM02484.1 - 0.32 9.3 16.0 0.49 8.7 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 KFM02484.1 - 4.6 4.9 10.7 4.2 5.1 3.7 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family CBFD_NFYB_HMF PF00808.18 KFM02485.1 - 2.5e-23 81.8 2.4 3.7e-23 81.3 0.5 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KFM02485.1 - 0.00011 22.2 0.0 0.0002 21.4 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Matrix PF00661.16 KFM02485.1 - 0.016 13.5 0.1 0.017 13.4 0.0 1.1 1 0 0 1 1 1 0 Viral matrix protein Bromo_TP PF07524.8 KFM02485.1 - 0.093 12.4 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated TPR_MLP1_2 PF07926.7 KFM02486.1 - 0.001 18.8 4.3 0.001 18.8 3.0 11.5 3 2 7 10 10 10 2 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 KFM02486.1 - 0.0029 16.8 61.6 0.0047 16.1 1.9 7.9 4 1 3 8 8 8 5 Reovirus sigma C capsid protein TSC22 PF01166.13 KFM02486.1 - 0.016 15.1 2.0 0.016 15.1 1.4 13.5 8 4 7 15 15 15 0 TSC-22/dip/bun family EMP24_GP25L PF01105.19 KFM02487.1 - 4.6e-34 117.7 0.3 5.1e-34 117.5 0.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Mtf2_C PF14061.1 KFM02488.1 - 1.2e-29 101.9 0.1 2.5e-29 100.9 0.1 1.6 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 PHD PF00628.24 KFM02488.1 - 8.7e-17 60.5 28.2 9.3e-12 44.4 5.6 2.4 2 0 0 2 2 2 2 PHD-finger DUF4537 PF15057.1 KFM02488.1 - 0.0022 17.7 0.0 0.0051 16.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) DUF1325 PF07039.6 KFM02488.1 - 0.0047 16.5 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 SGF29 tudor-like domain Prok-RING_1 PF14446.1 KFM02488.1 - 0.0073 16.0 3.9 0.0073 16.0 2.7 3.1 3 1 1 4 4 4 1 Prokaryotic RING finger family 1 C1_1 PF00130.17 KFM02488.1 - 0.012 15.2 1.3 0.012 15.2 0.9 3.0 3 1 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Chromo PF00385.19 KFM02488.1 - 0.063 12.9 0.0 0.19 11.4 0.0 1.9 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF3682 PF12446.3 KFM02488.1 - 0.067 13.4 3.0 0.12 12.6 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) PHD_2 PF13831.1 KFM02488.1 - 3.6 6.9 22.8 0.16 11.2 4.7 3.3 2 1 0 2 2 2 0 PHD-finger PIP49_C PF12260.3 KFM02489.1 - 6.5e-67 224.5 0.1 1.2e-66 223.6 0.1 1.5 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 PIP49_N PF14875.1 KFM02489.1 - 3.9e-51 172.8 0.3 3.9e-51 172.8 0.2 2.3 2 0 0 2 2 2 1 N-term cysteine-rich ER, FAM69 Ribosomal_L18p PF00861.17 KFM02490.1 - 6.9e-46 155.3 0.1 1.3e-45 154.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 KFM02490.1 - 2.8e-34 117.5 8.1 5.7e-34 116.5 5.6 1.5 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region DUF1476 PF07345.6 KFM02490.1 - 0.0055 16.9 0.2 0.011 15.9 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1476) RabGAP-TBC PF00566.13 KFM02491.1 - 1.3e-52 178.4 3.0 1.3e-52 178.4 2.1 2.0 3 0 0 3 3 3 1 Rab-GTPase-TBC domain DUF4224 PF13986.1 KFM02491.1 - 0.05 13.1 0.2 0.15 11.6 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) DUF1129 PF06570.6 KFM02491.1 - 0.059 12.6 0.2 0.059 12.6 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Surfac_D-trimer PF09006.6 KFM02491.1 - 0.16 11.6 8.5 9.4 6.0 0.2 4.6 4 0 0 4 4 4 0 Lung surfactant protein D coiled-coil trimerisation DUF2730 PF10805.3 KFM02491.1 - 0.46 10.2 31.4 0.15 11.8 2.1 5.1 3 1 2 5 5 5 0 Protein of unknown function (DUF2730) RPAP2_Rtr1 PF04181.8 KFM02492.1 - 1.4e-26 92.3 2.9 1.4e-26 92.3 2.0 2.6 2 1 0 2 2 2 1 Rtr1/RPAP2 family DUF4181 PF13789.1 KFM02492.1 - 0.073 13.0 3.2 0.76 9.7 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4181) Kinetochor_Ybp2 PF08568.5 KFM02493.1 - 2.5e-89 300.2 20.8 3.3e-89 299.8 14.4 1.2 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin zf-AD PF07776.10 KFM02493.1 - 0.0067 16.4 0.1 0.029 14.3 0.1 2.1 1 0 0 1 1 1 1 Zinc-finger associated domain (zf-AD) Ribosomal_L25p PF01386.14 KFM02493.1 - 0.057 13.5 0.1 0.35 11.0 0.0 2.2 2 0 0 2 2 2 0 Ribosomal L25p family DUF4580 PF15162.1 KFM02494.1 - 1.2e-56 190.5 0.8 1.3e-56 190.4 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4580) DUF4596 PF15363.1 KFM02495.1 - 1.6e-27 95.1 6.2 1.6e-27 95.1 4.3 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4596) BTB PF00651.26 KFM02496.1 - 2.9e-22 78.7 0.0 5.2e-21 74.7 0.0 2.2 1 1 1 2 2 2 1 BTB/POZ domain DnaJ_CXXCXGXG PF00684.14 KFM02496.1 - 0.0072 16.3 0.4 0.013 15.4 0.3 1.4 1 0 0 1 1 1 1 DnaJ central domain Abhydrolase_6 PF12697.2 KFM02497.1 - 1.3e-35 123.3 0.0 1.7e-35 122.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFM02497.1 - 5.9e-23 81.6 0.0 7.1e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFM02497.1 - 5.6e-15 55.3 0.0 9.4e-15 54.6 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 KFM02497.1 - 8.7e-05 21.1 0.0 0.0053 15.2 0.0 2.1 2 0 0 2 2 2 2 Ndr family Hydrolase_4 PF12146.3 KFM02497.1 - 0.00064 19.5 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase PGAP1 PF07819.8 KFM02497.1 - 0.0084 15.7 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 KFM02497.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Bromodomain PF00439.20 KFM02498.1 - 4.2e-35 119.5 2.7 4.5e-22 77.7 0.3 2.7 2 0 0 2 2 2 2 Bromodomain LMBR1 PF04791.11 KFM02498.1 - 0.019 13.5 0.0 0.12 10.9 0.0 2.3 2 1 0 2 2 2 0 LMBR1-like membrane protein DUF2369 PF10179.4 KFM02499.1 - 4.8e-67 226.1 3.9 2.2e-61 207.5 1.5 2.1 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2369) fn3 PF00041.16 KFM02499.1 - 2.1e-07 30.9 2.0 0.017 15.2 0.0 4.5 5 0 0 5 5 5 3 Fibronectin type III domain CopK PF11525.3 KFM02499.1 - 0.012 15.2 0.2 2.5 7.7 0.0 2.8 3 0 0 3 3 3 0 Copper resistance protein K PA-IIL PF07472.6 KFM02499.1 - 0.097 12.8 0.2 1.2 9.3 0.1 2.5 1 1 1 2 2 2 0 Fucose-binding lectin II (PA-IIL) KH_1 PF00013.24 KFM02500.1 - 6.4e-35 118.6 6.1 8.6e-14 50.9 0.2 5.4 5 0 0 5 5 5 4 KH domain KH_3 PF13014.1 KFM02500.1 - 1.2e-24 85.4 10.1 5.9e-11 41.7 0.2 5.9 7 0 0 7 7 7 2 KH domain SAM_1 PF00536.25 KFM02500.1 - 3e-14 52.9 0.1 6.2e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFM02500.1 - 5.2e-12 45.4 0.1 1.4e-11 44.1 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SLS PF14611.1 KFM02500.1 - 3.1e-08 33.2 0.4 0.057 12.8 0.3 3.9 1 1 3 4 4 4 2 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.12 KFM02500.1 - 0.0013 18.2 0.6 0.26 10.8 0.1 2.8 3 0 0 3 3 3 1 KH domain SpoIIIAH PF12685.2 KFM02500.1 - 0.02 14.3 0.8 0.075 12.5 0.1 2.2 2 1 1 3 3 3 0 SpoIIIAH-like protein KH_4 PF13083.1 KFM02500.1 - 0.084 12.5 0.3 0.23 11.1 0.2 1.8 1 0 0 1 1 1 0 KH domain fn3 PF00041.16 KFM02501.1 - 1.8e-07 31.1 0.2 4.7e-07 29.8 0.0 1.8 2 0 0 2 2 2 1 Fibronectin type III domain DUF918 PF06033.6 KFM02501.1 - 0.11 11.9 0.6 0.33 10.4 0.1 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF918) Drc1-Sld2 PF11719.3 KFM02502.1 - 0.015 14.4 2.2 0.015 14.4 1.5 3.4 2 1 1 3 3 3 0 DNA replication and checkpoint protein RhoGAP PF00620.22 KFM02503.1 - 2.5e-40 137.5 0.2 3e-40 137.3 0.1 1.1 1 0 0 1 1 1 1 RhoGAP domain DAG_kinase_N PF14513.1 KFM02503.1 - 0.066 13.4 0.0 0.091 12.9 0.0 1.2 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus DUF3136 PF11334.3 KFM02503.1 - 0.077 12.4 0.1 0.26 10.7 0.0 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3136) PAH PF02671.16 KFM02503.1 - 0.14 11.7 0.9 0.32 10.6 0.3 1.8 2 0 0 2 2 2 0 Paired amphipathic helix repeat MFS_1 PF07690.11 KFM02504.1 - 6.9e-29 100.6 35.7 2e-16 59.6 10.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2046 PF09755.4 KFM02505.1 - 1.9e-134 447.4 46.6 2.3e-134 447.1 32.3 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) SLAM PF06214.6 KFM02505.1 - 0.11 12.4 1.9 1.8 8.5 0.2 2.4 2 0 0 2 2 2 0 Signaling lymphocytic activation molecule (SLAM) protein Death PF00531.17 KFM02506.1 - 4.5e-20 71.2 0.0 8.8e-20 70.2 0.0 1.5 1 0 0 1 1 1 1 Death domain Involucrin_N PF10583.4 KFM02506.1 - 0.017 15.4 0.8 0.32 11.3 0.1 2.6 2 0 0 2 2 2 0 Involucrin of squamous epithelia N-terminus Ank PF00023.25 KFM02507.1 - 7.6e-197 628.2 71.0 1.2e-09 37.4 0.0 23.7 23 1 1 24 24 24 22 Ankyrin repeat Ank_2 PF12796.2 KFM02507.1 - 4.7e-193 626.1 85.4 7.6e-23 80.6 1.6 11.2 1 1 9 12 12 12 12 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFM02507.1 - 3.1e-127 413.0 45.3 6.7e-11 42.3 0.0 16.4 6 5 12 18 18 18 18 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM02507.1 - 1e-124 393.7 41.2 2.5e-06 27.1 0.0 23.8 24 0 0 24 24 24 22 Ankyrin repeat Ank_5 PF13857.1 KFM02507.1 - 1.1e-120 390.9 46.1 1.3e-10 41.1 0.0 17.0 3 3 17 20 20 20 19 Ankyrin repeats (many copies) ZU5 PF00791.15 KFM02507.1 - 2.2e-40 136.5 2.9 1e-37 127.9 0.1 2.8 2 0 0 2 2 2 2 ZU5 domain BTB PF00651.26 KFM02509.1 - 9e-29 99.7 5.2 6.5e-17 61.5 0.1 3.8 4 0 0 4 4 4 3 BTB/POZ domain Ras PF00071.17 KFM02509.1 - 1.1e-23 83.3 0.0 2.5e-23 82.2 0.0 1.6 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KFM02509.1 - 8.1e-13 48.9 0.0 3.1e-12 47.0 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Tmem26 PF09772.4 KFM02510.1 - 2.2e-104 348.6 9.7 2.5e-104 348.4 6.7 1.0 1 0 0 1 1 1 1 Transmembrane protein 26 CLAMP PF14769.1 KFM02512.1 - 2.5e-23 82.1 0.0 3.4e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 ARID PF01388.16 KFM02513.1 - 7e-20 70.6 0.0 1.7e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain MCP_N PF05581.7 KFM02514.1 - 0.015 15.4 0.3 0.037 14.1 0.1 1.6 1 1 0 1 1 1 0 Vibrio chemotaxis protein N terminus UvrD_C PF13361.1 KFM02514.1 - 0.034 13.5 9.3 0.011 15.2 4.6 1.4 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain zf-C2H2_4 PF13894.1 KFM02514.1 - 0.042 14.1 1.7 0.22 11.9 1.2 2.3 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KFM02514.1 - 0.043 14.1 1.6 0.16 12.4 1.0 2.2 2 0 0 2 2 1 0 Zinc finger, C2H2 type Tropomyosin PF00261.15 KFM02514.1 - 0.055 12.5 19.9 0.087 11.8 13.8 1.2 1 0 0 1 1 1 0 Tropomyosin DUF342 PF03961.8 KFM02514.1 - 0.77 8.1 10.5 0.65 8.3 6.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Amidase PF01425.16 KFM02514.1 - 0.94 8.2 4.1 1.3 7.8 2.9 1.1 1 0 0 1 1 1 0 Amidase FUSC-like PF12805.2 KFM02514.1 - 1 8.1 6.4 0.18 10.6 1.4 1.8 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS FUSC PF04632.7 KFM02514.1 - 1.7 6.9 5.9 2.7 6.2 4.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.10 KFM02514.1 - 2 7.5 14.8 5.3 6.1 10.1 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit APG6 PF04111.7 KFM02514.1 - 6.2 5.7 18.8 4.3 6.2 5.6 1.6 1 1 1 2 2 2 0 Autophagy protein Apg6 Cache_2 PF08269.6 KFM02514.1 - 7 6.6 8.4 11 6.1 1.6 2.9 2 1 1 3 3 3 0 Cache domain UPF0449 PF15136.1 KFM02514.1 - 9 6.5 9.4 10 6.4 2.2 2.9 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 DUF1875 PF08961.5 KFM02515.1 - 1.7e-128 427.0 13.6 2e-128 426.8 9.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1875) MIT PF04212.13 KFM02515.1 - 3.4e-05 23.6 1.1 0.00011 22.0 0.7 1.9 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DivIC PF04977.10 KFM02515.1 - 0.00044 19.6 2.2 0.00044 19.6 1.5 2.3 2 1 0 2 2 2 1 Septum formation initiator HALZ PF02183.13 KFM02515.1 - 0.0012 18.5 2.7 0.0012 18.5 1.9 1.9 2 0 0 2 2 2 1 Homeobox associated leucine zipper DUF972 PF06156.8 KFM02515.1 - 0.0037 17.6 0.8 0.0037 17.6 0.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF972) TPR_11 PF13414.1 KFM02515.1 - 0.0088 15.6 0.6 0.018 14.6 0.4 1.5 1 0 0 1 1 1 1 TPR repeat DUF904 PF06005.7 KFM02515.1 - 0.0092 16.2 2.1 0.0092 16.2 1.4 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF904) TPR_7 PF13176.1 KFM02515.1 - 0.065 13.0 0.2 0.21 11.4 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 KFM02515.1 - 0.24 11.3 3.1 0.19 11.7 0.9 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat JmjC PF02373.17 KFM02516.1 - 2.4e-11 43.8 0.0 1.3e-10 41.5 0.0 2.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-C3HC4_2 PF13923.1 KFM02516.1 - 2.1 8.4 6.5 5.8 7.0 4.5 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_3 PF07649.7 KFM02516.1 - 9.8 6.3 8.3 20 5.2 5.8 1.5 1 0 0 1 1 1 0 C1-like domain TB2_DP1_HVA22 PF03134.14 KFM02517.1 - 3.8e-31 106.6 10.6 6.5e-31 105.9 7.3 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF2306 PF10067.4 KFM02517.1 - 0.041 14.0 0.2 0.071 13.2 0.2 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2306) Gag_p30 PF02093.11 KFM02518.1 - 8.8e-26 90.4 0.1 1e-25 90.1 0.0 1.0 1 0 0 1 1 1 1 Gag P30 core shell protein Gag_p24 PF00607.15 KFM02518.1 - 0.03 13.8 0.0 0.037 13.5 0.0 1.1 1 0 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) rpo132 PF12415.3 KFM02518.1 - 0.087 11.7 0.1 0.19 10.7 0.1 1.5 1 0 0 1 1 1 0 Poxvirus DNA dependent RNA polymerase DUF2693 PF10902.3 KFM02518.1 - 0.097 12.5 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2693) Vinculin PF01044.14 KFM02519.1 - 3.3e-189 631.1 26.6 7e-177 590.3 14.3 2.1 1 1 1 2 2 2 2 Vinculin family AAA_32 PF13654.1 KFM02519.1 - 0.091 11.3 8.6 0.85 8.2 0.1 3.1 2 1 1 3 3 3 0 AAA domain LRR_8 PF13855.1 KFM02520.1 - 1.3e-58 194.6 59.7 1.3e-14 53.6 1.3 5.3 1 1 4 6 6 6 6 Leucine rich repeat LRR_4 PF12799.2 KFM02520.1 - 5.3e-31 105.7 35.0 1.1e-06 28.0 0.3 6.7 5 1 1 6 6 6 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFM02520.1 - 3e-30 104.5 0.3 9.4e-13 47.9 0.1 3.1 1 1 3 4 4 4 4 Leucine rich repeats (6 copies) LRR_1 PF00560.28 KFM02520.1 - 1.1e-19 67.3 37.1 0.011 15.6 0.5 11.1 11 0 0 11 11 11 8 Leucine Rich Repeat LRR_6 PF13516.1 KFM02520.1 - 2.2e-12 45.6 28.6 0.076 13.1 0.7 9.7 8 1 1 9 9 9 5 Leucine Rich repeat LRR_7 PF13504.1 KFM02520.1 - 2.7e-09 35.7 40.0 0.075 13.2 0.6 10.8 11 0 0 11 11 11 3 Leucine rich repeat LRR_9 PF14580.1 KFM02520.1 - 4.9e-07 29.4 3.2 0.013 15.0 0.3 3.2 1 1 2 3 3 3 3 Leucine-rich repeat LRRNT PF01462.13 KFM02520.1 - 4.4e-06 26.0 0.9 4.4e-06 26.0 0.6 2.5 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_2 PF07723.8 KFM02520.1 - 0.073 13.5 6.7 12 6.6 0.1 6.5 7 1 1 8 8 8 0 Leucine Rich Repeat EphA2_TM PF14575.1 KFM02520.1 - 0.17 12.2 0.1 0.69 10.3 0.1 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Vinculin PF01044.14 KFM02521.1 - 4.3e-42 144.2 0.7 4.8e-42 144.0 0.5 1.0 1 0 0 1 1 1 1 Vinculin family TMEM89 PF15098.1 KFM02521.1 - 0.11 12.4 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 TMEM89 protein family DnaJ PF00226.26 KFM02522.1 - 6.8e-18 64.1 0.2 2e-17 62.6 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain Luteo_P1-P2 PF08467.5 KFM02522.1 - 0.0026 16.6 0.2 0.0031 16.3 0.1 1.1 1 0 0 1 1 1 1 Luteovirus RNA polymerase P1-P2/replicase SIR2 PF02146.12 KFM02523.1 - 4.1e-62 209.0 0.0 7.2e-62 208.2 0.0 1.4 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 KFM02523.1 - 0.0049 16.4 0.2 0.0086 15.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 KFM02523.1 - 0.027 14.2 0.0 6.1 6.6 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain FancD2 PF14631.1 KFM02523.1 - 0.47 7.4 1.2 0.66 7.0 0.8 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease I-set PF07679.11 KFM02524.1 - 6.7e-107 349.5 0.0 1.7e-21 75.8 0.0 5.4 5 0 0 5 5 5 5 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM02524.1 - 2.5e-53 178.1 0.1 1.5e-10 41.0 0.0 5.9 5 0 0 5 5 5 5 Immunoglobulin domain Ig_3 PF13927.1 KFM02524.1 - 1.8e-35 121.2 0.0 5.3e-07 30.0 0.0 6.2 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.20 KFM02524.1 - 4.5e-31 106.7 0.6 3.3e-06 27.1 0.0 6.2 5 0 0 5 5 5 5 Immunoglobulin domain V-set PF07686.12 KFM02524.1 - 1.7e-20 72.9 6.1 0.0014 18.5 0.0 7.2 6 2 0 6 6 6 5 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM02524.1 - 8.8e-12 44.7 0.7 0.36 10.7 0.0 6.5 5 1 0 5 5 5 4 CD80-like C2-set immunoglobulin domain C1-set PF07654.10 KFM02524.1 - 0.00031 20.6 0.4 1.3 9.1 0.0 5.1 5 0 0 5 5 5 1 Immunoglobulin C1-set domain Receptor_2B4 PF11465.3 KFM02524.1 - 0.00099 19.0 0.5 1.7 8.6 0.0 4.8 5 0 0 5 5 5 1 Natural killer cell receptor 2B4 BiPBP_C PF06832.7 KFM02524.1 - 0.0012 18.7 0.0 2.1 8.3 0.0 4.3 5 0 0 5 5 5 1 Penicillin-Binding Protein C-terminus Family HLH PF00010.21 KFM02525.1 - 3.2e-18 65.1 0.1 4.7e-18 64.6 0.1 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Citrate_synt PF00285.16 KFM02525.1 - 0.0093 14.7 0.3 0.01 14.5 0.2 1.0 1 0 0 1 1 1 1 Citrate synthase DERM PF14704.1 KFM02525.1 - 0.062 13.2 0.3 0.87 9.5 0.0 2.1 2 0 0 2 2 2 0 Dermatopontin DUF1295 PF06966.7 KFM02525.1 - 0.083 12.1 0.1 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) PhzC-PhzF PF02567.11 KFM02526.1 - 3.4e-58 197.0 0.0 4.2e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein DAP_epimerase PF01678.14 KFM02526.1 - 0.058 13.2 0.0 5 7.0 0.0 2.4 2 0 0 2 2 2 0 Diaminopimelate epimerase RRM_6 PF14259.1 KFM02527.1 - 4.9e-26 90.4 0.1 7.3e-12 45.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFM02527.1 - 1.8e-21 75.5 0.0 1.2e-10 40.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM02527.1 - 0.0007 19.4 0.0 1.6 8.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dna2 PF08696.6 KFM02528.1 - 2e-69 233.1 0.3 4.9e-69 231.8 0.2 1.7 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.1 KFM02528.1 - 7.1e-47 159.3 5.0 3.3e-31 108.2 0.1 2.8 2 1 1 3 3 3 2 AAA domain AAA_11 PF13086.1 KFM02528.1 - 3e-38 131.7 2.5 9e-19 67.9 0.1 3.0 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.1 KFM02528.1 - 3.5e-13 49.5 0.0 2.2e-12 46.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.2 KFM02528.1 - 8.8e-11 41.6 0.0 1.4e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.13 KFM02528.1 - 3.4e-08 33.2 0.2 0.2 11.1 0.0 3.9 4 0 0 4 4 4 3 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 KFM02528.1 - 6.9e-08 32.1 0.1 2e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain CbiA PF01656.18 KFM02528.1 - 0.00019 20.8 0.0 0.00056 19.3 0.0 1.8 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Cas_Cas4 PF01930.12 KFM02528.1 - 0.00058 19.8 4.2 0.23 11.3 0.6 3.5 2 1 0 2 2 2 2 Domain of unknown function DUF83 SRP54 PF00448.17 KFM02528.1 - 0.00096 18.6 0.0 0.0023 17.4 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain UvrD_C_2 PF13538.1 KFM02528.1 - 0.0023 18.0 0.0 0.0051 16.9 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.1 KFM02528.1 - 0.0049 16.8 0.1 0.022 14.7 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 KFM02528.1 - 0.0074 15.6 0.1 0.016 14.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.16 KFM02528.1 - 0.0087 15.3 3.6 0.015 14.6 0.0 2.7 2 1 1 3 3 3 1 UvrD/REP helicase N-terminal domain MobB PF03205.9 KFM02528.1 - 0.0092 15.6 0.1 0.025 14.2 0.1 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B PhoH PF02562.11 KFM02528.1 - 0.012 14.8 1.8 0.025 13.8 0.1 2.5 3 1 0 3 3 3 0 PhoH-like protein UvrD_C PF13361.1 KFM02528.1 - 0.012 15.0 3.5 0.82 9.0 0.0 2.9 2 1 0 3 3 3 0 UvrD-like helicase C-terminal domain cobW PF02492.14 KFM02528.1 - 0.013 14.9 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF853 PF05872.7 KFM02528.1 - 0.014 13.7 0.1 0.022 13.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA PF00004.24 KFM02528.1 - 0.018 15.2 0.0 0.044 13.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 KFM02528.1 - 0.026 14.0 0.1 0.054 13.0 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 KFM02528.1 - 0.034 14.9 0.0 0.15 12.8 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KFM02528.1 - 0.054 13.8 3.5 0.12 12.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain Helicase_RecD PF05127.9 KFM02528.1 - 0.08 12.5 0.0 0.27 10.8 0.0 1.9 2 0 0 2 2 1 0 Helicase Mito_carr PF00153.22 KFM02529.1 - 5.8e-72 237.4 7.3 5.5e-24 83.7 0.8 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tet_JBP PF12851.2 KFM02530.1 - 1.7e-49 167.4 0.1 5.7e-49 165.7 0.1 1.9 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily zf-CXXC PF02008.15 KFM02530.1 - 6.1e-05 22.7 28.8 6.1e-05 22.7 20.0 2.5 2 0 0 2 2 2 1 CXXC zinc finger domain DBC1 PF14443.1 KFM02531.1 - 1.8e-57 192.3 0.0 1.8e-57 192.3 0.0 2.3 2 0 0 2 2 2 1 DBC1 S1-like PF14444.1 KFM02531.1 - 1.1e-34 117.9 0.8 1.9e-34 117.1 0.5 1.4 1 0 0 1 1 1 1 S1-like SAP PF02037.22 KFM02531.1 - 2.4e-08 33.2 5.2 4.1e-08 32.5 1.3 2.5 2 0 0 2 2 2 1 SAP domain MIP-T3 PF10243.4 KFM02531.1 - 0.00077 18.0 34.1 0.00077 18.0 23.6 3.9 4 0 0 4 4 4 1 Microtubule-binding protein MIP-T3 Stork_head PF10264.4 KFM02532.1 - 6e-32 109.6 0.1 1.3e-31 108.5 0.1 1.6 1 0 0 1 1 1 1 Winged helix Storkhead-box1 domain Helicase_C PF00271.26 KFM02533.1 - 2.8e-26 91.1 0.0 6.2e-26 90.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain GUCT PF08152.7 KFM02533.1 - 1.4e-17 63.4 0.0 2.8e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 GUCT (NUC152) domain BBS1 PF14779.1 KFM02533.1 - 0.037 12.9 0.0 0.069 12.1 0.0 1.4 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 1 GUCT PF08152.7 KFM02534.1 - 2.9e-29 100.9 0.0 6.4e-29 99.7 0.0 1.6 2 0 0 2 2 2 1 GUCT (NUC152) domain Helicase_C PF00271.26 KFM02534.1 - 1.8e-25 88.5 0.0 4.7e-25 87.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CPL PF08144.6 KFM02534.1 - 0.015 15.1 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 CPL (NUC119) domain FTR PF01913.13 KFM02534.1 - 0.04 13.6 0.1 0.35 10.5 0.0 2.1 2 0 0 2 2 2 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase KBP_C PF12309.3 KFM02535.1 - 5e-135 450.2 10.7 5e-135 450.2 7.4 2.1 2 0 0 2 2 2 1 KIF-1 binding protein C terminal TPR_12 PF13424.1 KFM02535.1 - 1e-06 28.5 12.0 0.0025 17.7 1.2 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFM02535.1 - 0.042 13.4 0.5 0.042 13.4 0.3 4.4 6 0 0 6 6 6 0 Tetratricopeptide repeat RGS PF00615.14 KFM02535.1 - 0.046 13.8 0.5 0.046 13.8 0.4 2.9 3 1 0 3 3 3 0 Regulator of G protein signaling domain TPR_7 PF13176.1 KFM02535.1 - 0.085 12.7 11.1 0.54 10.1 0.4 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFM02535.1 - 0.25 12.0 1.4 23 6.0 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 KFM02535.1 - 0.34 10.9 5.9 1.6 8.8 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFM02535.1 - 5 7.1 12.4 1.1 9.1 0.2 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Serglycin PF04360.7 KFM02536.1 - 3.5e-22 78.7 0.0 3.8e-22 78.6 0.0 1.0 1 0 0 1 1 1 1 Serglycin Vps26 PF03643.10 KFM02537.1 - 2.6e-131 436.4 6.9 3e-131 436.2 4.8 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 KFM02537.1 - 0.014 15.2 1.2 0.53 10.0 0.0 3.3 3 1 1 4 4 4 0 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KFM02537.1 - 0.058 13.5 0.0 0.2 11.7 0.0 2.1 1 1 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain DUF3553 PF12073.3 KFM02537.1 - 0.11 11.8 0.1 0.21 10.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3553) SUV3_C PF12513.3 KFM02538.1 - 1.5e-17 62.7 0.0 4e-17 61.3 0.0 1.8 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 KFM02538.1 - 1.8e-12 46.9 0.0 5.6e-12 45.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Hexokinase_2 PF03727.11 KFM02539.1 - 4.5e-192 635.1 1.6 1.2e-95 319.3 0.0 2.3 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 KFM02539.1 - 3.1e-153 506.7 0.0 8.1e-82 273.5 0.0 2.3 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 KFM02540.1 - 8.1e-172 567.4 0.3 4e-87 290.8 0.0 2.3 2 0 0 2 2 2 2 Hexokinase Hexokinase_2 PF03727.11 KFM02540.1 - 1e-170 565.1 2.0 1.2e-98 329.2 0.0 3.2 3 0 0 3 3 3 3 Hexokinase Sec23_helical PF04815.10 KFM02540.1 - 0.016 14.6 0.0 0.043 13.2 0.0 1.8 1 0 0 1 1 1 0 Sec23/Sec24 helical domain DUF1997 PF09366.5 KFM02540.1 - 0.041 13.6 0.0 3.4 7.3 0.0 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1997) F420_ligase PF01996.11 KFM02540.1 - 0.23 10.4 0.6 17 4.3 0.0 2.9 3 0 0 3 3 3 0 F420-0:Gamma-glutamyl ligase 7tm_1 PF00001.16 KFM02541.1 - 1.9e-59 200.8 21.7 2.4e-59 200.5 15.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM02541.1 - 4.5e-11 42.4 25.1 5.8e-11 42.0 17.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Git3 PF11710.3 KFM02541.1 - 0.00097 18.7 7.5 0.00097 18.7 5.2 2.5 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Herpes_US9 PF06072.6 KFM02541.1 - 0.23 11.3 1.2 0.97 9.3 0.0 2.7 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Tetraspannin PF00335.15 KFM02542.1 - 7.7e-38 129.9 10.2 9.9e-38 129.6 7.0 1.1 1 0 0 1 1 1 1 Tetraspanin family CD20 PF04103.10 KFM02542.1 - 0.00047 20.1 0.1 0.001 18.9 0.1 1.6 1 0 0 1 1 1 1 CD20-like family Claudin_2 PF13903.1 KFM02542.1 - 0.00073 19.2 1.3 0.00092 18.9 0.1 1.7 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF2075 PF09848.4 KFM02542.1 - 0.046 12.6 0.0 0.059 12.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF202 PF02656.10 KFM02542.1 - 0.22 11.7 0.8 0.79 9.9 0.5 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF202) DUF2367 PF10164.4 KFM02542.1 - 2.3 8.1 7.4 0.24 11.2 0.8 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2367) TctB PF07331.6 KFM02542.1 - 4.1 7.0 12.7 0.32 10.6 3.8 2.3 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF2207 PF09972.4 KFM02542.1 - 5.1 5.5 5.0 0.6 8.6 0.7 1.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) CAAD PF14159.1 KFM02542.1 - 5.6 6.6 6.1 0.69 9.5 1.0 2.0 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Macro PF01661.16 KFM02543.1 - 9.2e-25 86.8 0.1 1.6e-24 86.0 0.1 1.4 1 0 0 1 1 1 1 Macro domain Histone PF00125.19 KFM02543.1 - 7.1e-22 77.3 0.0 1.7e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFM02543.1 - 0.01 15.8 0.0 0.026 14.5 0.0 1.7 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Clp_N PF02861.15 KFM02543.1 - 0.035 14.0 1.0 0.13 12.2 0.0 2.4 3 0 0 3 3 3 0 Clp amino terminal domain Pyr_redox_2 PF07992.9 KFM02544.1 - 1.5e-16 60.8 1.1 0.00035 20.5 0.4 3.7 1 1 2 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFM02544.1 - 1.1e-09 38.5 0.3 2.3e-09 37.5 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFM02544.1 - 2.1e-08 34.4 0.1 0.00072 19.6 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFM02544.1 - 4e-08 32.5 0.1 1.2e-05 24.4 0.0 2.1 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KFM02544.1 - 3e-07 29.6 1.3 0.0045 15.9 0.0 3.1 2 1 1 3 3 3 3 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KFM02544.1 - 3.8e-07 29.9 1.1 0.046 13.4 0.0 3.2 2 1 1 3 3 3 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KFM02544.1 - 6.6e-05 21.9 0.3 0.034 13.0 0.1 2.4 3 0 0 3 3 3 2 Lycopene cyclase protein GIDA PF01134.17 KFM02544.1 - 0.00055 18.9 5.0 0.74 8.6 0.0 3.2 2 1 1 3 3 3 2 Glucose inhibited division protein A HI0933_like PF03486.9 KFM02544.1 - 0.00078 18.0 2.0 0.38 9.1 0.3 2.9 2 1 1 3 3 3 2 HI0933-like protein Trp_halogenase PF04820.9 KFM02544.1 - 0.039 12.6 1.1 1.7 7.2 0.2 2.3 2 0 0 2 2 2 0 Tryptophan halogenase Amino_oxidase PF01593.19 KFM02544.1 - 0.061 12.3 0.1 0.8 8.6 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Sulfotransfer_1 PF00685.22 KFM02545.1 - 2.9e-49 167.7 0.0 3.6e-49 167.4 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 KFM02545.1 - 0.00046 21.1 1.6 0.00084 20.3 0.7 1.8 1 1 0 1 1 1 1 Sulfotransferase family SapB_2 PF03489.12 KFM02546.1 - 8.6e-46 153.4 45.1 2.5e-13 49.7 1.5 6.4 7 0 0 7 7 7 4 Saposin-like type B, region 2 SapB_1 PF05184.10 KFM02546.1 - 3e-42 141.7 20.5 7.5e-13 47.9 0.2 5.9 5 0 0 5 5 5 4 Saposin-like type B, region 1 SapA PF02199.10 KFM02546.1 - 3.1e-17 62.0 8.4 3.1e-17 62.0 5.9 3.6 3 0 0 3 3 3 2 Saposin A-type domain TLE_N PF03920.10 KFM02546.1 - 0.00022 21.0 1.8 0.032 14.0 0.1 2.8 2 1 0 2 2 2 2 Groucho/TLE N-terminal Q-rich domain Imm5 PF14423.1 KFM02546.1 - 0.24 10.9 3.9 7.5 6.1 0.3 2.8 3 0 0 3 3 3 0 Immunity protein Imm5 SapB_1 PF05184.10 KFM02547.1 - 1e-20 73.0 10.9 5.6e-12 45.1 1.5 2.8 3 0 0 3 3 3 2 Saposin-like type B, region 1 SapB_2 PF03489.12 KFM02547.1 - 7.7e-15 54.5 5.7 3.2e-09 36.6 1.1 3.1 3 0 0 3 3 3 2 Saposin-like type B, region 2 Ig_2 PF13895.1 KFM02548.1 - 3.2e-06 27.1 0.2 2.9e-05 24.1 0.3 2.3 2 1 0 2 2 2 1 Immunoglobulin domain V-set PF07686.12 KFM02548.1 - 7.4e-05 22.6 0.2 0.00039 20.2 0.1 2.0 1 1 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 KFM02548.1 - 0.0065 16.5 0.2 1.4 9.0 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 KFM02548.1 - 0.023 14.5 0.0 9.3 6.1 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin I-set domain Nucleoside_tran PF01733.13 KFM02550.1 - 2.4e-66 224.0 6.6 2.4e-66 224.0 4.6 2.0 1 1 1 2 2 2 1 Nucleoside transporter MFS_1 PF07690.11 KFM02550.1 - 0.00022 20.0 17.2 0.00022 20.0 11.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NRPS PF08415.5 KFM02550.1 - 0.33 10.7 1.4 0.48 10.2 0.0 1.9 2 0 0 2 2 2 0 Nonribosomal peptide synthase ZU5 PF00791.15 KFM02551.1 - 3.4e-36 123.0 0.0 6.5e-36 122.1 0.0 1.5 1 0 0 1 1 1 1 ZU5 domain Death PF00531.17 KFM02551.1 - 1.4e-13 50.3 0.1 2.4e-13 49.6 0.1 1.4 1 0 0 1 1 1 1 Death domain I-set PF07679.11 KFM02551.1 - 1.5e-10 40.7 0.0 3.6e-09 36.3 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin I-set domain TSP_1 PF00090.14 KFM02551.1 - 3.4e-10 39.8 26.6 1.1e-06 28.5 6.3 2.8 2 0 0 2 2 2 2 Thrombospondin type 1 domain Ig_2 PF13895.1 KFM02551.1 - 1.3e-09 38.0 0.3 5.2e-07 29.6 0.0 3.3 3 0 0 3 3 3 1 Immunoglobulin domain Ig_3 PF13927.1 KFM02551.1 - 0.0018 18.7 0.5 0.019 15.4 0.0 2.9 3 0 0 3 3 3 1 Immunoglobulin domain PTCRA PF15028.1 KFM02551.1 - 0.0048 16.4 0.1 0.013 15.0 0.1 1.7 1 0 0 1 1 1 1 Pre-T-cell antigen receptor ig PF00047.20 KFM02551.1 - 0.012 15.6 0.0 0.012 15.6 0.0 3.2 4 0 0 4 4 4 0 Immunoglobulin domain Telethonin PF09470.5 KFM02551.1 - 0.025 14.0 0.0 0.052 13.0 0.0 1.4 1 0 0 1 1 1 0 Telethonin protein Pterin_4a PF01329.14 KFM02552.1 - 4.1e-32 109.7 0.1 4.6e-32 109.6 0.0 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Pyridoxal_deC PF00282.14 KFM02553.1 - 1.3e-19 69.9 0.0 2.2e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KFM02553.1 - 4.3e-15 55.3 0.0 3.3e-14 52.4 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KFM02553.1 - 0.0014 17.8 0.0 0.002 17.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase TroA PF01297.12 KFM02553.1 - 0.04 13.1 0.0 0.077 12.2 0.0 1.3 1 0 0 1 1 1 0 Periplasmic solute binding protein family SLA_LP_auto_ag PF05889.8 KFM02553.1 - 0.13 10.7 0.0 0.31 9.4 0.0 1.6 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Vitellogenin_N PF01347.17 KFM02554.1 - 2.1e-13 49.3 0.0 3e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Lipoprotein amino terminal region DUF1943 PF09172.6 KFM02554.1 - 0.00014 20.8 0.1 0.00078 18.4 0.0 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF1943) START PF01852.14 KFM02555.1 - 4.5e-24 84.9 0.0 5e-23 81.5 0.0 2.0 1 1 0 1 1 1 1 START domain ADAM_spacer1 PF05986.9 KFM02556.1 - 8.9e-26 89.9 0.1 1.4e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 TSP_1 PF00090.14 KFM02556.1 - 7.7e-24 83.5 58.2 2.7e-10 40.1 5.2 6.0 5 0 0 5 5 5 4 Thrombospondin type 1 domain Reprolysin PF01421.14 KFM02556.1 - 2.7e-22 79.3 0.0 6.3e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.1 KFM02556.1 - 6e-16 58.9 0.8 1.4e-15 57.7 0.6 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Pep_M12B_propep PF01562.14 KFM02556.1 - 2.5e-15 56.4 0.0 4.9e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_3 PF13582.1 KFM02556.1 - 1.2e-10 41.9 0.2 2.2e-10 41.1 0.2 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFM02556.1 - 1.2e-10 41.7 1.8 2.1e-10 40.9 0.8 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFM02556.1 - 7.7e-09 35.3 0.3 1.6e-08 34.3 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KFM02556.1 - 0.0012 18.6 0.2 0.0021 17.7 0.1 1.5 1 0 0 1 1 1 1 Matrixin PLAC PF08686.6 KFM02556.1 - 0.002 18.3 4.8 0.002 18.3 3.3 2.8 3 0 0 3 3 1 1 PLAC (protease and lacunin) domain Peptidase_M7 PF02031.11 KFM02556.1 - 0.048 13.3 0.1 0.048 13.3 0.1 1.9 2 0 0 2 2 1 0 Streptomyces extracellular neutral proteinase (M7) family PTPlike_phytase PF14566.1 KFM02557.1 - 1.3e-71 239.4 0.0 3.2e-38 131.1 0.0 2.7 2 0 0 2 2 2 2 Inositol hexakisphosphate Y_phosphatase PF00102.22 KFM02557.1 - 7.6e-05 22.1 0.0 0.051 12.8 0.0 2.4 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KFM02557.1 - 0.0043 17.3 0.1 0.15 12.2 0.0 3.0 2 1 0 2 2 2 1 Tyrosine phosphatase family eIF_4EBP PF05456.6 KFM02558.1 - 2.9e-17 62.4 0.1 3e-17 62.3 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) LRR_8 PF13855.1 KFM02559.1 - 8.2e-15 54.3 4.4 1.3e-07 31.2 2.6 3.0 1 1 2 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 KFM02559.1 - 2e-14 52.8 3.3 1.3e-05 24.6 0.2 3.9 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM02559.1 - 3.5e-12 44.5 4.2 0.19 11.9 0.1 6.1 6 0 0 6 6 6 4 Leucine Rich Repeat LRR_7 PF13504.1 KFM02559.1 - 3e-07 29.5 7.6 0.096 12.9 0.1 5.8 6 0 0 6 6 6 2 Leucine rich repeat LRR_6 PF13516.1 KFM02559.1 - 2.3e-06 27.0 0.7 9 6.7 0.0 5.5 6 0 0 6 6 6 2 Leucine Rich repeat LRR_9 PF14580.1 KFM02559.1 - 0.039 13.5 0.2 0.14 11.7 0.1 1.7 1 1 1 2 2 2 0 Leucine-rich repeat 7tm_1 PF00001.16 KFM02560.1 - 3.4e-60 203.3 17.6 3.4e-60 203.3 12.2 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM02560.1 - 4.7e-10 39.0 15.1 9.3e-10 38.0 10.5 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Pyrophosphatase PF00719.14 KFM02561.1 - 2.3e-56 189.5 0.3 2.8e-56 189.2 0.2 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Arf PF00025.16 KFM02562.1 - 3.7e-64 215.1 0.0 4.2e-64 214.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KFM02562.1 - 7.8e-10 38.2 0.0 9.7e-10 37.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KFM02562.1 - 6.1e-09 35.0 0.2 2e-06 26.7 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 KFM02562.1 - 1.7e-07 30.8 0.0 1.9e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM02562.1 - 3.7e-07 30.6 0.0 5.4e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KFM02562.1 - 1.4e-05 25.0 0.0 2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFM02562.1 - 4.6e-05 22.9 0.0 0.00056 19.3 0.0 1.9 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFM02562.1 - 0.0016 17.6 0.0 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 KFM02562.1 - 0.14 11.6 0.0 0.33 10.4 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AKAP7_NLS PF10469.4 KFM02563.1 - 1.1e-58 198.3 0.1 1.4e-58 198.0 0.1 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain KH_1 PF00013.24 KFM02563.1 - 3.6e-11 42.5 1.2 6.3e-11 41.7 0.9 1.4 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 KFM02563.1 - 8.7e-09 34.8 1.0 2e-08 33.6 0.3 1.9 2 0 0 2 2 2 1 KH domain 2_5_RNA_ligase2 PF13563.1 KFM02563.1 - 0.0012 18.6 0.0 0.0022 17.7 0.0 1.5 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily KH_2 PF07650.12 KFM02563.1 - 0.013 15.0 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 KH domain UPF0158 PF03682.8 KFM02563.1 - 0.11 12.1 0.1 0.24 10.9 0.0 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0158) DUF2110 PF09883.4 KFM02564.1 - 0.022 14.3 0.0 0.03 13.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2110) RTP801_C PF07809.6 KFM02565.1 - 1.7e-40 137.2 0.0 2.1e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 RTP801 C-terminal region DUF1977 PF09320.6 KFM02566.1 - 7.1e-43 145.2 0.2 1.2e-42 144.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 KFM02566.1 - 2e-27 94.6 1.3 3.1e-27 94.1 0.9 1.3 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.1 KFM02566.1 - 0.032 13.6 0.0 2.6 7.4 0.0 2.4 2 0 0 2 2 2 0 A repeated domain in UCH-protein CDI PF02234.14 KFM02568.1 - 1.6e-22 79.0 3.0 1.7e-22 78.9 2.1 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor RRM_1 PF00076.17 KFM02569.1 - 8.1e-18 63.8 0.0 1.2e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM02569.1 - 4e-11 42.7 0.0 5.8e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM02569.1 - 3.6e-10 39.5 0.0 4.9e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BTB_2 PF02214.17 KFM02570.1 - 5.6e-06 26.4 0.0 1.9e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Ets PF00178.17 KFM02571.1 - 1.4e-32 111.6 2.3 1.4e-32 111.6 1.6 1.9 2 0 0 2 2 2 1 Ets-domain SAM_PNT PF02198.11 KFM02571.1 - 6.5e-24 83.5 0.1 1.8e-23 82.0 0.0 1.7 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain HSF_DNA-bind PF00447.12 KFM02571.1 - 0.031 14.4 0.1 0.073 13.2 0.1 1.7 1 0 0 1 1 1 0 HSF-type DNA-binding FbpA PF05833.6 KFM02571.1 - 0.047 12.2 0.0 0.061 11.8 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Patatin PF01734.17 KFM02573.1 - 8.5e-13 48.6 3.3 5.5e-11 42.7 2.3 2.1 1 1 0 1 1 1 1 Patatin-like phospholipase Patatin PF01734.17 KFM02574.1 - 6.9e-08 32.6 1.3 4.9e-06 26.6 0.9 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase Ion_trans PF00520.26 KFM02575.1 - 5e-34 117.3 8.3 9.4e-34 116.4 4.5 1.9 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 KFM02575.1 - 1.2e-28 99.0 0.1 1.9e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.11 KFM02575.1 - 1.4e-13 50.3 6.0 1.4e-13 50.3 4.2 2.5 3 0 0 3 3 3 1 Ion channel PKD_channel PF08016.7 KFM02575.1 - 6.2e-05 21.5 0.6 0.00011 20.7 0.4 1.4 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 KFM02576.1 - 3.1e-35 121.2 5.1 3.1e-35 121.2 3.6 1.9 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 KFM02576.1 - 5.8e-29 100.1 0.1 9.2e-29 99.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.11 KFM02576.1 - 2.4e-14 52.7 4.8 2.4e-14 52.7 3.3 2.5 2 0 0 2 2 2 1 Ion channel PKD_channel PF08016.7 KFM02576.1 - 0.00079 17.9 0.8 0.00079 17.9 0.6 1.5 2 0 0 2 2 2 1 Polycystin cation channel DUF202 PF02656.10 KFM02576.1 - 3.9 7.7 5.7 89 3.4 0.0 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Ion_trans PF00520.26 KFM02577.1 - 2.5e-33 115.0 11.0 4.4e-33 114.2 6.5 1.9 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 KFM02577.1 - 1.5e-27 95.6 0.0 3.2e-27 94.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.11 KFM02577.1 - 7.6e-13 47.9 6.0 7.6e-13 47.9 4.1 2.8 3 0 0 3 3 3 1 Ion channel PKD_channel PF08016.7 KFM02577.1 - 3.9e-05 22.2 0.5 3.9e-05 22.2 0.3 2.1 1 1 0 2 2 2 1 Polycystin cation channel DUF423 PF04241.10 KFM02577.1 - 0.22 11.4 1.0 0.36 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF423) DUF202 PF02656.10 KFM02577.1 - 1.3 9.2 4.4 49 4.2 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF202) Asp PF00026.18 KFM02578.1 - 2.5e-85 286.5 8.8 2.8e-85 286.3 6.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KFM02578.1 - 2.6e-14 53.5 0.6 8.3e-14 51.8 0.4 1.8 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal A1_Propeptide PF07966.7 KFM02578.1 - 0.0013 18.4 1.9 0.0023 17.6 1.3 1.4 1 0 0 1 1 1 1 A1 Propeptide MFS_1 PF07690.11 KFM02580.1 - 1.5e-35 122.5 30.5 2.1e-20 72.7 6.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KFM02580.1 - 0.011 15.4 6.2 6 6.7 0.0 4.2 4 0 0 4 4 4 0 MFS_1 like family SPOC PF07744.8 KFM02581.1 - 1.4e-30 106.2 0.0 2.5e-30 105.4 0.0 1.4 1 0 0 1 1 1 1 SPOC domain RRM_1 PF00076.17 KFM02581.1 - 2.8e-19 68.4 0.0 1.9e-12 46.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM02581.1 - 2.7e-17 62.5 0.0 4.7e-09 36.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM02581.1 - 1.1e-10 41.1 0.0 3.7e-06 26.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFM02581.1 - 2.8e-07 30.2 0.0 0.00048 19.8 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KFM02581.1 - 7e-05 22.6 0.0 0.003 17.3 0.0 2.4 2 0 0 2 2 2 1 RNA binding motif Ion_trans PF00520.26 KFM02582.1 - 3.1e-32 111.4 8.5 3.1e-32 111.4 5.9 1.5 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 KFM02582.1 - 1.8e-29 101.8 0.0 3.8e-29 100.7 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.11 KFM02582.1 - 4.4e-10 39.1 4.1 4.4e-10 39.1 2.8 2.5 2 0 0 2 2 2 1 Ion channel DUF202 PF02656.10 KFM02582.1 - 0.82 9.9 7.1 34 4.7 0.0 3.5 2 1 0 2 2 2 0 Domain of unknown function (DUF202) SNF PF00209.13 KFM02583.1 - 3.5e-222 738.5 32.4 4.3e-222 738.2 22.5 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Homeobox PF00046.24 KFM02584.1 - 4.4e-25 87.0 6.4 5.3e-25 86.7 4.4 1.1 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFM02584.1 - 0.0002 20.9 0.1 0.00034 20.2 0.1 1.3 1 0 0 1 1 1 1 Homeobox KN domain Staygreen PF12638.2 KFM02584.1 - 0.011 15.3 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 0 Staygreen protein PRA-CH PF01502.13 KFM02584.1 - 0.095 12.3 0.2 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Phosphoribosyl-AMP cyclohydrolase AdoHcyase PF05221.12 KFM02585.1 - 9.9e-121 401.7 0.0 1.2e-120 401.5 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 KFM02585.1 - 1.1e-81 272.4 2.3 1.7e-81 271.8 1.6 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 KFM02585.1 - 1.7e-09 37.1 0.0 3.6e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 KFM02585.1 - 4.4e-05 22.9 0.2 9.1e-05 21.8 0.0 1.6 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain THF_DHG_CYH_C PF02882.14 KFM02585.1 - 0.00016 20.8 1.3 0.00062 18.8 0.9 1.8 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.15 KFM02585.1 - 0.00075 19.6 0.5 0.0027 17.7 0.4 1.9 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 KFM02585.1 - 0.00092 19.4 0.7 0.0029 17.8 0.5 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding TrkA_N PF02254.13 KFM02585.1 - 0.002 18.1 0.3 0.0073 16.2 0.2 2.0 1 1 0 1 1 1 1 TrkA-N domain Malic_M PF03949.10 KFM02585.1 - 0.0023 17.5 0.7 0.018 14.6 0.0 2.1 2 0 0 2 2 2 1 Malic enzyme, NAD binding domain AlaDh_PNT_C PF01262.16 KFM02585.1 - 0.0083 15.7 3.1 0.075 12.5 0.3 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.16 KFM02585.1 - 0.019 14.5 2.8 0.85 9.1 2.0 2.4 1 1 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_10 PF13460.1 KFM02585.1 - 0.056 13.4 0.1 0.2 11.6 0.0 2.0 2 0 0 2 2 2 0 NADH(P)-binding G-alpha PF00503.15 KFM02586.1 - 7.4e-127 423.2 2.6 8.3e-127 423.0 1.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KFM02586.1 - 4.4e-14 52.1 0.5 5.1e-13 48.6 0.0 2.7 2 1 0 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 KFM02586.1 - 0.003 18.0 0.7 0.97 9.9 0.0 2.9 3 0 0 3 3 3 2 Miro-like protein 7tm_1 PF00001.16 KFM02587.1 - 1.9e-41 141.9 9.8 2.2e-41 141.6 6.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR19-TM PF15176.1 KFM02587.1 - 0.8 9.4 2.6 6.9 6.4 0.0 2.4 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain Ank_2 PF12796.2 KFM02588.1 - 3e-08 33.8 0.4 1.3e-07 31.8 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFM02588.1 - 5.7e-08 32.1 1.7 0.00016 21.3 0.1 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 KFM02588.1 - 2.8e-07 30.1 0.2 0.0097 16.0 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat zf-MYND PF01753.13 KFM02588.1 - 1.9e-06 27.6 14.9 4e-06 26.5 10.3 1.6 1 0 0 1 1 1 1 MYND finger Ank_4 PF13637.1 KFM02588.1 - 2.1e-05 24.8 0.2 0.0047 17.4 0.0 3.1 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM02588.1 - 0.038 14.2 0.6 0.28 11.4 0.2 2.5 2 1 0 2 2 2 0 Ankyrin repeats (many copies) DUF581 PF04570.9 KFM02588.1 - 0.18 11.1 3.3 0.33 10.2 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF581) MORN PF02493.15 KFM02589.1 - 1.1e-09 37.4 11.3 9.2e-05 21.9 1.8 3.5 3 0 0 3 3 3 3 MORN repeat Peptidase_S28 PF05577.7 KFM02590.1 - 2.7e-83 279.9 0.0 3.3e-83 279.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 KFM02590.1 - 1.5e-06 28.2 0.0 5.1e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFM02590.1 - 1.1e-05 25.2 0.0 1.7e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFM02590.1 - 1.7e-05 24.5 1.1 2.6e-05 23.8 0.7 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFM02590.1 - 0.0046 16.1 0.1 0.008 15.4 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S37 PF05576.6 KFM02590.1 - 0.0055 15.2 0.0 0.011 14.2 0.0 1.4 1 0 0 1 1 1 1 PS-10 peptidase S37 Abhydrolase_2 PF02230.11 KFM02590.1 - 0.059 12.8 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF2920 PF11144.3 KFM02590.1 - 0.15 11.0 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Glyco_hydro_47 PF01532.15 KFM02591.1 - 1.6e-175 584.1 0.0 1.9e-175 583.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 UDPGP PF01704.13 KFM02592.1 - 6.8e-79 265.3 0.0 8.1e-79 265.0 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 KFM02592.1 - 0.00053 20.0 0.0 0.0013 18.8 0.0 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain Suppressor_APC PF11414.3 KFM02593.1 - 5.9e-31 106.1 4.0 1.5e-29 101.5 1.0 2.3 2 0 0 2 2 2 1 Adenomatous polyposis coli tumour suppressor protein GAS PF13851.1 KFM02593.1 - 0.0044 16.2 4.9 0.91 8.6 1.5 2.1 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding ING PF12998.2 KFM02593.1 - 0.065 13.5 1.3 0.23 11.7 0.1 2.1 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Spc7 PF08317.6 KFM02593.1 - 0.068 11.8 4.0 0.14 10.7 0.6 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF3134 PF11332.3 KFM02593.1 - 0.12 12.5 0.2 0.23 11.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3134) CENP-F_leu_zip PF10473.4 KFM02593.1 - 0.59 9.9 9.7 0.48 10.2 1.4 2.4 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.3 KFM02593.1 - 0.61 9.8 6.4 0.13 12.0 1.0 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.10 KFM02593.1 - 0.93 9.0 4.2 0.23 10.9 0.6 1.7 2 0 0 2 2 2 0 Septum formation initiator APG6 PF04111.7 KFM02593.1 - 5.7 5.8 10.1 2.8 6.8 2.0 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 IncA PF04156.9 KFM02593.1 - 9.2 5.8 8.5 1 8.8 1.1 2.1 2 0 0 2 2 2 0 IncA protein GDA1_CD39 PF01150.12 KFM02594.1 - 1.6e-95 320.1 0.0 2.1e-95 319.7 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF3902 PF13042.1 KFM02594.1 - 0.018 14.3 1.4 0.029 13.6 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3902) TMEM141 PF15110.1 KFM02595.1 - 2e-18 66.4 0.1 2.5e-18 66.1 0.1 1.1 1 0 0 1 1 1 1 TMEM141 protein family GST_C_2 PF13410.1 KFM02596.1 - 5e-07 29.5 0.1 6.3e-07 29.2 0.1 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KFM02596.1 - 0.0015 18.5 0.0 0.005 16.8 0.0 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFM02596.1 - 0.0031 17.9 0.0 0.004 17.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glyco_transf_10 PF00852.14 KFM02597.1 - 1.3e-113 379.1 0.7 1.5e-113 378.9 0.5 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) mIF3 PF14877.1 KFM02597.1 - 0.12 11.7 0.1 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial translation initiation factor Pou PF00157.12 KFM02598.1 - 9.7e-39 130.8 0.2 2.1e-38 129.8 0.1 1.6 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.24 KFM02598.1 - 4.2e-19 67.9 0.5 2e-18 65.7 0.2 2.1 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 KFM02598.1 - 0.0036 16.9 0.5 0.0091 15.6 0.1 1.9 2 0 0 2 2 2 1 Homeobox KN domain HTH_19 PF12844.2 KFM02598.1 - 0.012 15.6 0.0 5.5 7.1 0.0 2.5 1 1 0 2 2 2 0 Helix-turn-helix domain HTH_31 PF13560.1 KFM02598.1 - 0.085 13.0 0.1 0.77 9.9 0.0 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain NPDC1 PF06809.6 KFM02599.1 - 3e-84 282.7 7.6 3.6e-84 282.4 5.3 1.1 1 0 0 1 1 1 1 Neural proliferation differentiation control-1 protein (NPDC1) Shisa PF13908.1 KFM02599.1 - 0.021 14.9 0.3 0.043 13.9 0.2 1.6 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Lipocalin PF00061.18 KFM02600.1 - 0.0003 20.7 0.0 0.0003 20.7 0.0 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin PF00061.18 KFM02601.1 - 4.7e-28 97.9 0.0 5.4e-28 97.8 0.0 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin PF00061.18 KFM02602.1 - 6.7e-17 61.8 0.0 8.2e-17 61.5 0.0 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family WD40 PF00400.27 KFM02603.1 - 3.5e-11 42.5 0.8 3.5e-11 42.5 0.6 2.4 2 0 0 2 2 2 1 WD domain, G-beta repeat HTH_3 PF01381.17 KFM02604.1 - 6.9e-13 48.2 0.2 9.7e-13 47.7 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix MBF1 PF08523.5 KFM02604.1 - 5.5e-08 32.7 1.1 9.8e-08 31.9 0.2 1.8 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_19 PF12844.2 KFM02604.1 - 1.1e-05 25.4 0.1 1.4e-05 25.0 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 KFM02604.1 - 0.00022 21.3 0.0 0.0003 20.9 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.1 KFM02604.1 - 0.096 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Ras PF00071.17 KFM02605.1 - 8e-12 44.8 0.1 1e-05 24.9 0.2 2.3 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KFM02605.1 - 3.7e-08 33.8 0.0 3.7e-08 33.8 0.0 3.5 3 1 0 3 3 3 1 Miro-like protein Arf PF00025.16 KFM02605.1 - 5.3e-06 25.7 0.1 1.8e-05 24.0 0.1 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFM02605.1 - 0.0018 18.2 0.0 0.005 16.7 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 KFM02605.1 - 0.019 14.4 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Kunitz_BPTI PF00014.18 KFM02606.1 - 6.4e-36 122.3 20.0 1.3e-18 66.9 4.4 2.5 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain Lipocalin PF00061.18 KFM02606.1 - 2.2e-27 95.8 0.0 3.1e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family DNA_pol_A_exo1 PF01612.15 KFM02607.1 - 2.7e-23 82.3 0.0 2e-22 79.5 0.0 2.2 2 0 0 2 2 2 1 3'-5' exonuclease Mut7-C PF01927.11 KFM02607.1 - 4.4e-14 52.6 0.1 1.2e-13 51.3 0.1 1.8 1 0 0 1 1 1 1 Mut7-C RNAse domain Fels1 PF05666.6 KFM02607.1 - 0.038 13.3 0.4 0.078 12.3 0.0 1.8 2 0 0 2 2 2 0 Fels-1 Prophage Protein-like TRC8_N PF13705.1 KFM02608.1 - 2.2e-136 455.4 27.6 2.5e-136 455.2 19.2 1.0 1 0 0 1 1 1 1 TRC8 N-terminal domain zf-RING_2 PF13639.1 KFM02608.1 - 1.5e-11 43.9 9.0 1.5e-11 43.9 6.2 2.5 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 KFM02608.1 - 8.9e-08 32.1 8.9 3.4e-07 30.2 6.2 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KFM02608.1 - 1.3e-07 31.5 6.6 1.3e-07 31.5 4.6 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM02608.1 - 9.7e-07 28.3 6.9 9.7e-07 28.3 4.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM02608.1 - 1e-06 28.3 6.9 2.3e-06 27.2 4.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KFM02608.1 - 1.9e-06 27.4 6.2 1.9e-06 27.4 4.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFM02608.1 - 0.00048 19.9 7.5 0.0013 18.5 5.2 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 KFM02608.1 - 0.13 11.7 6.0 0.24 10.9 4.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 KFM02608.1 - 0.15 11.7 5.0 0.33 10.6 3.4 1.6 1 0 0 1 1 1 0 RING-type zinc-finger RINGv PF12906.2 KFM02608.1 - 0.21 11.6 5.4 0.54 10.3 3.7 1.7 1 0 0 1 1 1 0 RING-variant domain Orai-1 PF07856.7 KFM02608.1 - 1 8.9 7.7 0.52 9.8 3.6 1.9 2 0 0 2 2 2 0 Mediator of CRAC channel activity FANCL_C PF11793.3 KFM02608.1 - 4.9 7.1 7.9 30 4.6 5.5 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain HSP70 PF00012.15 KFM02609.1 - 0.012 13.5 0.1 0.13 10.1 0.0 2.0 2 0 0 2 2 2 0 Hsp70 protein Exonuc_X-T_C PF08411.5 KFM02609.1 - 0.15 11.0 0.1 0.22 10.5 0.1 1.1 1 0 0 1 1 1 0 Exonuclease C-terminal Ig_2 PF13895.1 KFM02610.1 - 8.8e-45 150.7 11.8 1.8e-12 47.2 0.1 5.4 5 0 0 5 5 5 5 Immunoglobulin domain I-set PF07679.11 KFM02610.1 - 8.9e-30 102.3 3.7 1e-07 31.7 0.1 6.5 5 3 0 5 5 5 4 Immunoglobulin I-set domain Ig_3 PF13927.1 KFM02610.1 - 4.5e-27 94.3 19.5 1.5e-08 35.0 0.3 6.1 6 2 0 6 6 6 4 Immunoglobulin domain ig PF00047.20 KFM02610.1 - 3.5e-21 75.0 9.9 6.7e-06 26.1 0.0 5.9 5 0 0 5 5 5 4 Immunoglobulin domain V-set PF07686.12 KFM02610.1 - 2.4e-20 72.5 7.5 0.00032 20.5 0.1 7.9 4 2 1 5 5 5 4 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM02610.1 - 8.9e-11 41.5 10.1 1.3e-07 31.4 0.7 4.7 4 1 0 4 4 4 2 CD80-like C2-set immunoglobulin domain C1-set PF07654.10 KFM02610.1 - 1.2e-07 31.5 4.6 0.031 14.2 0.0 5.1 4 2 0 4 4 4 2 Immunoglobulin C1-set domain Herpes_gE PF02480.11 KFM02610.1 - 4.4e-05 21.9 0.0 0.0031 15.8 0.0 2.8 2 1 1 3 3 3 1 Alphaherpesvirus glycoprotein E C2-set PF05790.10 KFM02610.1 - 0.00013 21.8 0.1 0.54 10.2 0.0 4.6 4 1 1 5 5 5 1 Immunoglobulin C2-set domain DUF11 PF01345.13 KFM02610.1 - 0.079 13.0 1.8 0.17 11.9 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF11 Homeobox PF00046.24 KFM02611.1 - 2.1e-13 49.6 2.2 2.5e-13 49.4 1.5 1.1 1 0 0 1 1 1 1 Homeobox domain HTH_AsnC-type PF13404.1 KFM02611.1 - 0.035 13.6 0.0 0.073 12.6 0.0 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain CENP-B_N PF04218.8 KFM02611.1 - 0.11 11.9 0.4 0.4 10.1 0.0 2.0 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain ATP-synt_ab PF00006.20 KFM02612.1 - 4.8e-35 121.0 0.0 5.6e-25 88.0 0.0 2.2 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KFM02612.1 - 1.4e-16 60.9 0.0 2.6e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KFM02612.1 - 5.8e-09 36.0 0.2 1.1e-08 35.1 0.1 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain PAM2 PF07145.10 KFM02613.1 - 6.9e-07 28.3 0.1 6.9e-07 28.3 0.1 1.8 2 0 0 2 2 2 1 Ataxin-2 C-terminal region RRM_6 PF14259.1 KFM02614.1 - 3.7e-07 30.0 0.0 6.8e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM02614.1 - 9.8e-06 25.3 0.0 1.9e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFM02614.1 - 0.0015 18.1 0.0 0.0033 17.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_jaz PF12171.3 KFM02614.1 - 0.18 11.9 0.8 0.4 10.8 0.5 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM02614.1 - 0.69 10.2 3.4 1.5 9.0 2.4 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type CytochromB561_N PF09786.4 KFM02614.1 - 9.3 4.5 12.0 20 3.4 8.3 1.5 1 0 0 1 1 1 0 Cytochrome B561, N terminal C2 PF00168.25 KFM02616.1 - 7.5e-57 189.1 0.2 1.6e-17 63.1 0.0 7.1 7 0 0 7 7 7 6 C2 domain FerB PF08150.7 KFM02616.1 - 1.7e-37 127.3 0.0 3.7e-37 126.2 0.0 1.6 1 0 0 1 1 1 1 FerB (NUC096) domain FerI PF08151.7 KFM02616.1 - 2.6e-30 104.2 0.0 8.1e-30 102.6 0.0 1.9 1 0 0 1 1 1 1 FerI (NUC094) domain FerA PF08165.6 KFM02616.1 - 5.2e-14 51.6 0.1 1.3e-13 50.4 0.1 1.7 1 0 0 1 1 1 1 FerA (NUC095) domain Pex24p PF06398.6 KFM02616.1 - 1.2e-05 24.3 6.7 1.2e-05 24.3 4.6 4.1 3 1 1 4 4 4 2 Integral peroxisomal membrane peroxin PTEN_C2 PF10409.4 KFM02616.1 - 0.00068 19.3 0.0 0.0017 18.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein Synaptobrevin PF00957.16 KFM02616.1 - 8.7 6.0 4.9 20 4.8 3.4 1.6 1 0 0 1 1 1 0 Synaptobrevin Sec15 PF04091.7 KFM02617.1 - 3.2e-96 322.3 1.4 4.9e-96 321.7 1.0 1.3 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like adh_short PF00106.20 KFM02618.1 - 1.4e-07 31.5 0.1 2.7e-07 30.6 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFM02618.1 - 0.1 12.3 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Mtc PF03820.12 KFM02619.1 - 4.4e-100 334.2 0.1 5e-100 334.1 0.1 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier RBD-FIP PF09457.5 KFM02620.1 - 3e-20 71.7 8.3 6.9e-20 70.5 5.7 1.7 1 0 0 1 1 1 1 FIP domain Homeobox PF00046.24 KFM02621.1 - 1.6e-22 78.8 3.1 2.4e-22 78.2 2.2 1.3 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 KFM02621.1 - 0.042 12.9 0.3 0.077 12.0 0.2 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Polyketide_cyc PF03364.15 KFM02621.1 - 0.11 12.5 0.1 0.11 12.4 0.1 1.1 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport HA PF03457.9 KFM02621.1 - 0.13 12.4 2.5 0.18 11.9 1.7 1.4 1 1 0 1 1 1 0 Helicase associated domain Homeobox PF00046.24 KFM02622.1 - 2e-22 78.5 4.5 2.8e-22 78.0 3.2 1.2 1 0 0 1 1 1 1 Homeobox domain Denso_VP4 PF02336.10 KFM02622.1 - 0.16 10.9 0.0 0.19 10.6 0.0 1.0 1 0 0 1 1 1 0 Capsid protein VP4 SET PF00856.23 KFM02623.1 - 1.3e-11 45.1 0.6 2.1e-10 41.1 0.4 2.3 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 KFM02623.1 - 0.00031 20.5 11.5 0.00031 20.5 8.0 2.9 3 2 0 3 3 3 1 MYND finger zf-HIT PF04438.11 KFM02623.1 - 1.3 8.7 13.6 0.052 13.1 3.4 2.7 2 0 0 2 2 2 0 HIT zinc finger PA PF02225.17 KFM02624.1 - 2e-14 53.1 0.0 2.7e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 PA domain GH97_C PF14509.1 KFM02624.1 - 0.012 15.7 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation F-box-like PF12937.2 KFM02625.1 - 1.7e-08 34.0 0.6 1.7e-08 34.0 0.4 2.9 4 0 0 4 4 4 1 F-box-like F-box PF00646.28 KFM02625.1 - 6.2e-05 22.5 0.7 0.00043 19.8 0.1 2.4 2 0 0 2 2 2 1 F-box domain Borrelia_P83 PF05262.6 KFM02625.1 - 0.0013 17.1 7.8 0.0017 16.6 5.4 1.1 1 0 0 1 1 1 1 Borrelia P83/100 protein zf-C2H2 PF00096.21 KFM02625.1 - 0.0043 17.3 2.2 0.012 15.9 1.5 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM02625.1 - 0.018 15.3 2.3 0.078 13.3 1.6 2.2 1 0 0 1 1 1 0 C2H2-type zinc finger Exonuc_VII_L PF02601.10 KFM02625.1 - 0.03 13.5 8.5 0.052 12.7 5.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-C2H2_6 PF13912.1 KFM02625.1 - 0.081 12.8 0.4 0.26 11.2 0.2 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger UvrD_C PF13361.1 KFM02625.1 - 1.1 8.5 9.2 2 7.7 6.4 1.3 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain APG6 PF04111.7 KFM02625.1 - 4.5 6.2 15.5 30 3.5 11.3 1.9 2 0 0 2 2 2 0 Autophagy protein Apg6 zf-C2H2 PF00096.21 KFM02626.1 - 2.6e-14 52.5 16.5 3.4e-05 23.9 2.2 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM02626.1 - 2.7e-14 52.6 9.0 2.4e-08 33.8 0.9 4.7 5 1 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM02626.1 - 3.5e-06 26.9 27.7 0.00058 19.9 1.9 4.4 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM02626.1 - 0.0026 17.5 5.5 0.16 11.9 0.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KFM02626.1 - 0.0054 16.3 9.9 1.1 8.9 0.6 3.8 3 0 0 3 3 3 2 zinc-finger of a C2HC-type RRN7 PF11781.3 KFM02626.1 - 0.0092 15.4 5.7 0.051 13.0 0.2 3.1 3 0 0 3 3 3 1 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C2H2_jaz PF12171.3 KFM02626.1 - 0.23 11.6 3.2 2.5 8.3 0.2 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 KFM02626.1 - 0.25 11.1 10.5 0.19 11.5 3.5 2.9 1 1 2 3 3 3 0 BED zinc finger zf-met PF12874.2 KFM02626.1 - 0.71 10.1 8.9 0.53 10.5 0.4 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type SAS4 PF15460.1 KFM02627.1 - 3.1 7.7 9.1 0.37 10.6 2.6 2.0 2 0 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 DUF2924 PF11149.3 KFM02629.1 - 0.062 13.3 0.3 0.97 9.4 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2924) Yae1_N PF09811.4 KFM02633.1 - 5.3e-13 48.2 35.0 25 4.4 24.3 3.5 1 1 0 1 1 1 1 Essential protein Yae1, N terminal GDNF PF02351.11 KFM02634.1 - 1.4e-43 147.2 41.7 1.5e-20 73.4 4.5 3.1 3 0 0 3 3 3 3 GDNF/GAS1 domain Kelch_4 PF13418.1 KFM02635.1 - 3.3e-24 84.3 5.7 0.0012 18.5 0.1 6.9 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.20 KFM02635.1 - 2e-23 81.6 5.5 2e-05 24.0 0.0 6.5 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 KFM02635.1 - 5.3e-22 77.0 13.2 0.00025 21.0 0.1 7.0 7 0 0 7 7 6 5 Kelch motif Kelch_5 PF13854.1 KFM02635.1 - 1.2e-19 69.8 12.5 1.8e-05 24.5 0.0 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.1 KFM02635.1 - 1.6e-18 66.2 1.6 0.0065 16.6 0.0 6.8 6 0 0 6 6 6 6 Galactose oxidase, central domain Lectin_C PF00059.16 KFM02635.1 - 1e-16 61.4 0.3 1e-16 61.4 0.2 3.4 2 1 1 3 3 1 1 Lectin C-type domain PSI PF01437.20 KFM02635.1 - 4.8e-16 58.6 106.6 2.1e-10 40.6 6.7 7.6 7 0 0 7 7 5 5 Plexin repeat CUB PF00431.15 KFM02635.1 - 1e-12 48.1 0.0 3.3e-12 46.4 0.0 2.0 1 0 0 1 1 1 1 CUB domain Kelch_2 PF07646.10 KFM02635.1 - 2e-12 46.3 7.2 0.17 11.6 0.0 6.7 7 0 0 7 7 7 4 Kelch motif Laminin_EGF PF00053.19 KFM02635.1 - 0.0015 18.4 17.0 0.0015 18.4 11.8 8.6 6 3 2 8 8 4 2 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 KFM02635.1 - 0.013 15.6 11.3 0.013 15.6 7.8 9.1 8 3 0 8 8 3 0 EGF-like domain SIR2_2 PF13289.1 KFM02636.1 - 0.0058 16.5 2.1 0.02 14.7 0.0 3.1 4 1 0 4 4 4 1 SIR2-like domain NAD_binding_9 PF13454.1 KFM02636.1 - 0.19 11.4 0.1 0.97 9.1 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding HCO3_cotransp PF00955.16 KFM02637.1 - 1.7e-97 327.2 7.3 2.5e-97 326.6 5.1 1.1 1 0 0 1 1 1 1 HCO3- transporter family PTS_EIIA_2 PF00359.17 KFM02637.1 - 2.6e-07 30.4 0.0 5.7e-06 26.1 0.0 2.7 2 1 0 2 2 2 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Band_3_cyto PF07565.8 KFM02637.1 - 3.1e-06 26.8 0.0 1.3e-05 24.8 0.0 1.7 1 1 1 2 2 2 1 Band 3 cytoplasmic domain Sulfate_transp PF00916.15 KFM02637.1 - 0.018 14.0 6.6 1.6 7.6 0.1 3.4 2 1 1 3 3 3 0 Sulfate transporter family SprT-like PF10263.4 KFM02637.1 - 0.05 13.2 0.2 0.13 11.9 0.1 1.7 2 0 0 2 2 2 0 SprT-like family 7tm_1 PF00001.16 KFM02638.1 - 4.8e-78 261.8 11.8 6.2e-78 261.4 8.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM02638.1 - 5.5e-09 35.5 10.9 1e-08 34.6 7.5 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM02638.1 - 0.14 11.2 12.0 0.016 14.3 5.2 1.8 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Haemadin PF09065.5 KFM02638.1 - 0.16 11.5 0.4 0.42 10.2 0.1 1.8 2 0 0 2 2 2 0 Haemadin NADH-u_ox-rdase PF10785.4 KFM02638.1 - 0.46 10.7 3.3 0.51 10.6 0.1 2.6 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit DUF4491 PF14898.1 KFM02638.1 - 5.6 7.1 7.1 1.3 9.1 0.6 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4491) RVT_1 PF00078.22 KFM02639.1 - 0.041 13.2 0.0 0.072 12.4 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DDRGK PF09756.4 KFM02640.1 - 4.4e-67 225.1 32.1 4.4e-67 225.1 22.3 1.4 2 0 0 2 2 2 1 DDRGK domain PCI PF01399.22 KFM02640.1 - 7.4e-05 23.0 0.1 0.00015 22.0 0.0 1.5 1 0 0 1 1 1 1 PCI domain FeoC PF09012.5 KFM02640.1 - 0.00014 21.5 0.2 0.29 10.8 0.0 2.5 2 0 0 2 2 2 2 FeoC like transcriptional regulator UPF0181 PF03701.9 KFM02640.1 - 0.0047 16.1 0.0 0.023 13.9 0.0 2.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0181) HTH_DeoR PF08220.7 KFM02640.1 - 0.0067 15.9 0.2 2.3 7.8 0.0 2.4 2 0 0 2 2 2 2 DeoR-like helix-turn-helix domain CAF-1_p150 PF11600.3 KFM02640.1 - 0.044 13.1 42.0 0.059 12.7 29.1 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Cytochrom_C PF00034.16 KFM02640.1 - 2.1 9.2 0.0 2.1 9.2 0.0 3.1 1 1 1 3 3 3 0 Cytochrome c Spore_coat_CotO PF14153.1 KFM02640.1 - 3 7.2 28.4 5.9 6.2 19.7 1.5 1 0 0 1 1 1 0 Spore coat protein CotO U79_P34 PF03064.11 KFM02640.1 - 6.3 6.2 19.6 10 5.5 13.6 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Pox_G5 PF04599.7 KFM02640.1 - 6.9 5.2 9.2 9.5 4.7 6.4 1.3 1 0 0 1 1 1 0 Poxvirus G5 protein DDHD PF02862.12 KFM02640.1 - 9 6.0 11.7 13 5.4 8.1 1.5 1 0 0 1 1 1 0 DDHD domain Fez1 PF06818.10 KFM02641.1 - 7.2e-75 251.4 26.2 7.2e-75 251.4 18.1 2.3 2 0 0 2 2 2 1 Fez1 GAS PF13851.1 KFM02641.1 - 3 6.9 59.1 2.6 7.2 19.2 3.2 2 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding WEMBL PF05701.6 KFM02641.1 - 5.5 5.3 51.6 0.012 14.0 20.7 2.1 2 0 0 2 2 2 0 Weak chloroplast movement under blue light FAST_2 PF08368.7 KFM02642.1 - 7e-17 61.5 0.0 1.6e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 FAST kinase-like protein, subdomain 2 FAST_1 PF06743.10 KFM02642.1 - 1.1e-16 60.3 1.6 3.3e-15 55.5 0.0 3.5 4 0 0 4 4 4 1 FAST kinase-like protein, subdomain 1 RAP PF08373.5 KFM02642.1 - 7.5e-12 44.8 0.5 1.5e-11 43.9 0.3 1.5 1 0 0 1 1 1 1 RAP domain U-box PF04564.10 KFM02643.1 - 2.5e-26 91.4 0.1 5.7e-26 90.2 0.1 1.7 1 0 0 1 1 1 1 U-box domain zf-RING_5 PF14634.1 KFM02643.1 - 0.0001 21.9 6.5 0.0001 21.9 4.5 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 KFM02643.1 - 0.00021 21.0 5.5 0.00021 21.0 3.8 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFM02643.1 - 0.00075 19.4 6.9 0.00075 19.4 4.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM02643.1 - 0.00078 19.0 5.6 0.0035 16.9 3.9 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFM02643.1 - 0.0014 18.2 5.0 0.011 15.4 0.6 3.2 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 KFM02643.1 - 0.0018 17.9 5.1 0.0052 16.4 3.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 KFM02643.1 - 0.11 12.4 5.0 0.5 10.2 3.5 2.2 1 1 0 1 1 1 0 FYVE zinc finger zf-C3HC4_4 PF15227.1 KFM02643.1 - 0.26 11.2 12.5 0.075 12.9 5.5 2.7 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING Hormone_4 PF00220.12 KFM02644.1 - 0.00035 19.9 4.4 0.00063 19.1 3.0 1.4 1 0 0 1 1 1 1 Neurohypophysial hormones, N-terminal Domain Hormone_5 PF00184.12 KFM02645.1 - 6.2e-29 100.3 21.5 6.2e-29 100.3 14.9 1.5 2 0 0 2 2 2 1 Neurohypophysial hormones, C-terminal Domain Hormone_4 PF00220.12 KFM02645.1 - 0.001 18.4 5.0 0.001 18.4 3.5 3.0 2 0 0 2 2 2 1 Neurohypophysial hormones, N-terminal Domain MRP-S26 PF14943.1 KFM02646.1 - 3e-34 118.0 13.6 3.3e-34 117.8 9.5 1.0 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S26 MAP7 PF05672.6 KFM02646.1 - 0.22 10.9 18.1 0.27 10.6 12.6 1.1 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family APG6 PF04111.7 KFM02646.1 - 0.53 9.2 8.5 0.59 9.1 5.9 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3987 PF13148.1 KFM02646.1 - 6.7 5.1 8.7 7.9 4.9 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Y_phosphatase PF00102.22 KFM02647.1 - 9.2e-174 574.9 9.8 1.2e-88 296.4 0.4 2.1 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.15 KFM02647.1 - 7.6e-10 38.4 0.1 0.00077 19.0 0.0 2.7 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFM02647.1 - 4.3e-08 33.5 1.3 0.002 18.3 0.0 3.0 3 0 0 3 3 3 2 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KFM02647.1 - 2e-07 31.1 1.4 0.0023 17.9 0.0 3.2 3 0 0 3 3 3 2 Inositol hexakisphosphate Rifin_STEVOR PF02009.11 KFM02647.1 - 0.016 14.8 0.0 0.047 13.3 0.0 1.7 1 0 0 1 1 1 0 Rifin/stevor family EphA2_TM PF14575.1 KFM02647.1 - 0.024 15.0 0.0 0.085 13.2 0.0 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Tn7_Tnp_TnsA_C PF08721.6 KFM02647.1 - 0.076 13.0 0.0 8.2 6.5 0.0 3.4 3 1 0 3 3 3 0 TnsA endonuclease C terminal Y_phosphatase2 PF03162.8 KFM02647.1 - 0.19 11.0 2.1 2.7 7.3 0.0 3.1 3 0 0 3 3 3 0 Tyrosine phosphatase family DUF3149 PF11346.3 KFM02647.1 - 0.35 10.4 2.5 0.84 9.2 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) TMEM154 PF15102.1 KFM02647.1 - 1.7 8.3 15.7 29 4.3 10.9 2.5 1 1 0 1 1 1 0 TMEM154 protein family Adeno_E3_CR2 PF02439.10 KFM02647.1 - 2.1 7.9 6.9 2 8.0 1.8 2.5 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Fumble PF03630.9 KFM02649.1 - 4.6e-144 479.4 0.0 5.3e-144 479.2 0.0 1.0 1 0 0 1 1 1 1 Fumble zf-RING_2 PF13639.1 KFM02650.1 - 3e-06 26.9 2.0 5.8e-06 26.0 1.4 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_1 PF14446.1 KFM02650.1 - 0.0022 17.6 1.2 0.0034 17.0 0.8 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-C3HC4 PF00097.20 KFM02650.1 - 0.0029 17.2 2.8 0.0056 16.3 1.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Orthoreo_P10 PF07204.6 KFM02650.1 - 0.022 14.4 0.6 0.032 13.9 0.4 1.3 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 zf-RING_5 PF14634.1 KFM02650.1 - 0.027 14.2 2.2 0.044 13.5 1.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain DUF1301 PF06979.7 KFM02650.1 - 0.075 13.1 0.2 0.09 12.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1301) zf-C3HC4_3 PF13920.1 KFM02650.1 - 0.1 12.2 2.1 0.17 11.5 1.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFM02650.1 - 0.35 11.0 2.7 0.61 10.2 1.8 1.5 1 1 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KFM02650.1 - 0.99 9.4 6.0 0.12 12.4 1.3 1.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Amino_oxidase PF01593.19 KFM02651.1 - 2.2e-79 267.6 0.0 4.6e-79 266.5 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KFM02651.1 - 3.9e-15 55.6 0.6 9.6e-15 54.3 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFM02651.1 - 8e-07 28.2 0.0 1.9e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KFM02651.1 - 1.9e-06 28.1 0.3 4e-06 27.0 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFM02651.1 - 6.6e-06 25.2 0.8 9.7e-06 24.6 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KFM02651.1 - 0.00013 22.3 2.7 0.00019 21.7 0.4 2.3 2 1 1 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFM02651.1 - 0.00095 19.1 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KFM02651.1 - 0.0027 16.6 0.6 0.0041 16.0 0.4 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 KFM02651.1 - 0.0038 15.7 0.4 0.0091 14.5 0.3 1.7 1 1 0 1 1 1 1 HI0933-like protein Shikimate_DH PF01488.15 KFM02651.1 - 0.0039 17.2 0.0 0.009 16.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 KFM02651.1 - 0.0043 16.1 1.5 0.0094 15.0 0.3 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 KFM02651.1 - 0.011 14.8 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 KFM02651.1 - 0.013 14.6 0.2 0.03 13.4 0.1 1.6 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.1 KFM02651.1 - 0.04 13.6 0.4 0.14 11.9 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 KFM02651.1 - 0.042 13.4 0.1 0.078 12.5 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FMO-like PF00743.14 KFM02651.1 - 0.045 11.9 0.0 0.066 11.3 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like ThiF PF00899.16 KFM02651.1 - 0.05 13.4 0.1 0.096 12.5 0.0 1.5 1 0 0 1 1 1 0 ThiF family Lycopene_cycl PF05834.7 KFM02651.1 - 0.13 11.1 0.7 0.36 9.6 0.2 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.13 KFM02651.1 - 0.15 11.6 1.4 2.8 7.5 0.2 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 7tm_1 PF00001.16 KFM02652.1 - 3.4e-83 278.7 12.5 4.2e-83 278.4 8.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM02652.1 - 3.4e-17 62.4 6.5 6.5e-17 61.5 4.5 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM02652.1 - 3.7e-05 22.9 11.1 3.7e-05 22.9 7.7 1.9 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx Vinculin PF01044.14 KFM02654.1 - 7.2e-53 179.8 5.9 8e-53 179.7 4.1 1.0 1 0 0 1 1 1 1 Vinculin family CorA PF01544.13 KFM02654.1 - 0.051 12.6 0.5 0.082 11.9 0.3 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF349 PF03993.7 KFM02654.1 - 0.14 12.3 5.5 2.1 8.5 1.3 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) DUF3708 PF12501.3 KFM02654.1 - 0.16 11.7 3.5 3.2 7.5 0.2 2.0 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter LRR_8 PF13855.1 KFM02655.1 - 1.7e-53 178.2 28.1 2.8e-16 58.9 0.8 5.2 1 1 5 6 6 6 6 Leucine rich repeat LRR_4 PF12799.2 KFM02655.1 - 4.7e-30 102.6 19.7 1.7e-07 30.6 0.3 7.0 3 3 5 8 8 8 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM02655.1 - 4.3e-21 71.7 25.0 0.02 14.8 0.5 11.3 12 0 0 12 12 12 6 Leucine Rich Repeat LRR_5 PF13306.1 KFM02655.1 - 1.8e-20 72.9 0.0 4.2e-10 39.4 0.0 2.9 2 1 0 3 3 3 2 Leucine rich repeats (6 copies) LRR_7 PF13504.1 KFM02655.1 - 3e-12 44.6 18.4 0.55 10.6 0.0 10.6 11 0 0 11 11 10 3 Leucine rich repeat LRR_9 PF14580.1 KFM02655.1 - 3.6e-09 36.4 0.6 0.014 14.9 0.0 3.6 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.1 KFM02655.1 - 1.9e-07 30.4 26.0 1.2 9.4 0.0 10.3 10 1 1 11 11 10 2 Leucine Rich repeat LRRNT PF01462.13 KFM02655.1 - 4.5e-05 22.7 1.5 4.5e-05 22.7 1.1 2.6 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain HemY_N PF07219.8 KFM02655.1 - 0.013 15.0 0.2 0.028 13.9 0.1 1.5 1 0 0 1 1 1 0 HemY protein N-terminus UL97 PF06734.7 KFM02655.1 - 0.045 13.1 0.0 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 UL97 Ni_hydr_CYTB PF01292.15 KFM02655.1 - 0.075 12.4 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 ComGG PF14173.1 KFM02655.1 - 0.26 11.4 1.4 0.29 11.3 0.1 1.7 2 0 0 2 2 2 0 ComG operon protein 7 Vinculin PF01044.14 KFM02656.1 - 2.7e-213 710.8 21.4 3.1e-213 710.7 14.8 1.0 1 0 0 1 1 1 1 Vinculin family RVT_1 PF00078.22 KFM02657.1 - 2.1e-15 56.7 0.0 2.8e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1725 PF08333.6 KFM02657.1 - 0.96 8.8 3.7 12 5.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1725) Ndr PF03096.9 KFM02660.1 - 6.1e-123 408.8 0.0 7.2e-123 408.5 0.0 1.0 1 0 0 1 1 1 1 Ndr family Abhydrolase_6 PF12697.2 KFM02660.1 - 6.2e-15 55.7 0.0 8.8e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFM02660.1 - 0.0059 16.1 0.0 0.0087 15.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF4201 PF13870.1 KFM02661.1 - 3.7e-38 130.7 25.7 3.7e-38 130.7 17.8 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) AbiH PF14253.1 KFM02661.1 - 0.0035 16.9 7.7 0.0049 16.5 5.3 1.3 1 0 0 1 1 1 1 Bacteriophage abortive infection AbiH ASL_C2 PF14698.1 KFM02661.1 - 0.64 10.1 3.5 5.1 7.2 0.1 3.3 3 1 1 4 4 4 0 Argininosuccinate lyase C-terminal DUF948 PF06103.6 KFM02661.1 - 0.72 9.7 8.7 1.6 8.6 0.2 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) CCP_MauG PF03150.9 KFM02661.1 - 2.5 8.3 5.7 18 5.5 0.0 2.4 2 1 0 2 2 2 0 Di-haem cytochrome c peroxidase Pkinase PF00069.20 KFM02662.1 - 1.8e-61 207.5 0.6 2.2e-61 207.3 0.4 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM02662.1 - 4e-23 81.8 0.2 8.5e-23 80.7 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KFM02662.1 - 1e-09 38.4 0.0 3.9e-06 26.7 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFM02662.1 - 0.0041 16.7 0.1 0.012 15.1 0.0 1.8 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 KFM02662.1 - 0.0053 15.8 0.0 0.008 15.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_3 PF08447.6 KFM02662.1 - 0.032 14.3 0.1 0.083 13.0 0.1 1.7 1 0 0 1 1 1 0 PAS fold YrbL-PhoP_reg PF10707.4 KFM02662.1 - 0.096 12.0 1.2 1.2 8.4 0.0 2.5 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL DUF667 PF05018.8 KFM02664.1 - 5e-88 293.3 0.8 5.6e-88 293.1 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Peptidase_M10 PF00413.19 KFM02665.1 - 5.1e-57 191.9 0.0 7.6e-57 191.3 0.0 1.3 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.14 KFM02665.1 - 6.2e-44 147.4 15.2 1.4e-15 56.7 0.8 3.5 3 0 0 3 3 3 3 Hemopexin PG_binding_1 PF01471.13 KFM02665.1 - 1.7e-07 31.0 0.1 4e-07 29.8 0.1 1.6 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.19 KFM02665.1 - 0.0092 15.3 0.3 1.2 8.5 0.0 2.2 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.1 KFM02665.1 - 0.021 15.3 0.0 0.04 14.4 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KFM02665.1 - 0.04 13.8 0.1 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Metallopep PF12044.3 KFM02665.1 - 0.066 11.6 0.0 0.1 10.9 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M54 PF07998.6 KFM02665.1 - 0.097 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M54 Reprolysin_2 PF13574.1 KFM02665.1 - 0.1 12.6 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like HVSL PF09749.4 KFM02666.1 - 9.4e-46 155.7 0.0 1.1e-45 155.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein zf-H2C2_2 PF13465.1 KFM02667.1 - 2.9e-62 204.0 140.0 8.2e-11 41.6 1.0 17.8 18 0 0 18 18 18 15 Zinc-finger double domain zf-C2H2 PF00096.21 KFM02667.1 - 8.2e-57 186.2 153.0 3.8e-06 26.9 0.7 17.2 17 0 0 17 17 17 15 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM02667.1 - 3.9e-39 130.1 132.8 0.00013 22.0 2.9 16.9 17 0 0 17 17 17 14 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM02667.1 - 2.3e-22 78.4 86.0 0.0055 16.8 0.9 14.8 15 0 0 15 15 15 11 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFM02667.1 - 5.4e-18 64.2 104.4 0.008 16.0 0.6 16.2 16 0 0 16 16 16 10 C2H2-type zinc finger zf-met PF12874.2 KFM02667.1 - 1.5e-17 63.0 98.6 0.016 15.3 0.4 14.9 15 0 0 15 15 15 9 Zinc-finger of C2H2 type BolA PF01722.13 KFM02667.1 - 0.00021 21.2 28.6 0.71 9.8 0.1 8.2 6 2 3 9 9 9 3 BolA-like protein Antimicrobial_3 PF08025.6 KFM02667.1 - 0.15 11.7 1.0 32 4.3 0.0 3.9 3 0 0 3 3 3 0 Spider antimicrobial peptide PAT1 PF09770.4 KFM02667.1 - 4.6 5.3 9.2 8.7 4.4 6.4 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 cNMP_binding PF00027.24 KFM02668.1 - 1.6e-14 53.5 0.0 2.8e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Kinesin PF00225.18 KFM02669.1 - 5.9e-107 357.2 0.3 2.4e-106 355.2 0.0 2.1 2 0 0 2 2 2 1 Kinesin motor domain Ring_hydroxyl_B PF00866.13 KFM02669.1 - 1.1 8.9 12.9 0.047 13.3 2.7 2.7 3 0 0 3 3 3 0 Ring hydroxylating beta subunit CENP-F_leu_zip PF10473.4 KFM02669.1 - 1.8 8.3 63.7 0.62 9.9 16.7 4.4 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Zona_pellucida PF00100.18 KFM02670.1 - 1.8e-53 181.6 2.0 2.2e-53 181.3 1.4 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain EGF PF00008.22 KFM02670.1 - 9e-07 28.7 6.2 9e-07 28.7 4.3 1.9 2 0 0 2 2 2 1 EGF-like domain hEGF PF12661.2 KFM02670.1 - 0.00074 19.4 2.7 0.0028 17.6 1.9 2.1 1 0 0 1 1 1 1 Human growth factor-like EGF cEGF PF12662.2 KFM02670.1 - 0.0087 15.6 1.5 0.026 14.1 1.0 1.8 1 0 0 1 1 1 1 Complement Clr-like EGF-like EGF_3 PF12947.2 KFM02670.1 - 0.12 12.3 5.3 0.27 11.2 3.7 1.6 1 0 0 1 1 1 0 EGF domain EGF_2 PF07974.8 KFM02670.1 - 1.1 9.4 13.4 0.077 13.1 5.4 2.0 2 0 0 2 2 2 0 EGF-like domain 7tm_2 PF00002.19 KFM02671.1 - 2.6e-34 118.3 21.9 3.4e-34 117.9 15.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.16 KFM02671.1 - 1.4e-12 47.4 1.0 3.1e-12 46.4 0.7 1.6 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain 7tm_2 PF00002.19 KFM02672.1 - 6.7e-32 110.4 19.7 9e-32 110.0 13.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.16 KFM02672.1 - 8.1e-13 48.2 4.4 1.9e-12 47.0 3.1 1.7 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain 7tm_2 PF00002.19 KFM02673.1 - 7.7e-33 113.5 15.8 9.3e-33 113.3 11.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.16 KFM02673.1 - 2.4e-14 53.1 3.2 2.4e-14 53.1 2.2 2.0 2 0 0 2 2 2 1 Latrophilin/CL-1-like GPS domain Myosin_tail_1 PF01576.14 KFM02674.1 - 2.8e-12 45.2 59.6 1.9e-11 42.5 31.5 2.0 1 1 1 2 2 2 2 Myosin tail Fib_alpha PF08702.5 KFM02674.1 - 0.0016 18.5 31.6 0.051 13.6 3.4 3.4 1 1 2 3 3 3 3 Fibrinogen alpha/beta chain family Atg14 PF10186.4 KFM02674.1 - 0.0025 16.7 21.1 0.0025 16.7 14.6 2.5 1 1 1 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 MscS_porin PF12795.2 KFM02674.1 - 0.0039 16.5 45.9 0.022 14.0 5.9 3.6 1 1 2 3 3 3 2 Mechanosensitive ion channel porin domain Filament PF00038.16 KFM02674.1 - 0.0063 16.0 51.3 0.087 12.2 23.6 2.3 1 1 1 2 2 2 2 Intermediate filament protein ADIP PF11559.3 KFM02674.1 - 0.0079 16.1 53.6 0.075 12.9 8.0 3.9 1 1 1 3 3 3 2 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 KFM02674.1 - 0.013 14.6 7.8 0.15 11.2 1.6 2.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein ATG16 PF08614.6 KFM02674.1 - 0.015 15.1 55.1 0.054 13.3 8.8 3.8 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) APG6 PF04111.7 KFM02674.1 - 0.016 14.2 53.9 0.049 12.6 15.7 2.7 1 1 1 2 2 2 0 Autophagy protein Apg6 NPV_P10 PF05531.7 KFM02674.1 - 0.028 14.6 21.3 0.066 13.4 0.9 5.0 1 1 3 4 4 4 0 Nucleopolyhedrovirus P10 protein WEMBL PF05701.6 KFM02674.1 - 0.22 9.9 56.7 0.56 8.6 39.0 1.6 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Taxilin PF09728.4 KFM02674.1 - 0.3 10.1 54.4 1.5 7.8 32.0 2.2 1 1 1 2 2 2 0 Myosin-like coiled-coil protein DUF4200 PF13863.1 KFM02674.1 - 0.68 9.8 56.1 0.27 11.2 16.0 3.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) Spc7 PF08317.6 KFM02674.1 - 0.81 8.2 51.7 0.047 12.3 14.2 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein AAA_13 PF13166.1 KFM02674.1 - 1 7.7 39.1 0.095 11.1 18.3 2.1 1 1 1 2 2 2 0 AAA domain GAS PF13851.1 KFM02674.1 - 1.1 8.4 56.4 0.52 9.4 17.4 3.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding CALCOCO1 PF07888.6 KFM02674.1 - 1.3 7.2 45.4 0.18 10.0 10.6 2.4 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Laminin_II PF06009.7 KFM02674.1 - 2.3 8.0 28.7 0.089 12.5 5.3 4.0 1 1 3 4 4 4 0 Laminin Domain II DUF3584 PF12128.3 KFM02674.1 - 2.8 5.1 50.4 0.42 7.8 16.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Peptidase_S46 PF10459.4 KFM02674.1 - 3.7 5.8 26.9 4.6 5.5 18.6 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF972 PF06156.8 KFM02674.1 - 3.8 7.8 45.0 0.29 11.4 4.1 4.7 1 1 4 5 5 5 0 Protein of unknown function (DUF972) MCPsignal PF00015.16 KFM02674.1 - 3.9 6.9 14.0 1.6 8.1 0.9 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3450 PF11932.3 KFM02674.1 - 5.7 6.1 39.5 0.081 12.1 8.9 3.9 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) GLE1 PF07817.8 KFM02674.1 - 6.2 5.6 14.8 0.24 10.3 3.5 2.9 2 1 1 3 3 3 0 GLE1-like protein TPR_MLP1_2 PF07926.7 KFM02674.1 - 9.8 5.9 57.3 1.4 8.7 15.7 3.6 2 1 2 4 4 3 0 TPR/MLP1/MLP2-like protein IRS PF02174.12 KFM02675.1 - 1.6e-29 101.4 0.0 2.5e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 PTB domain (IRS-1 type) RNA_pol_A_bac PF01000.21 KFM02676.1 - 3.4e-40 136.6 0.0 4.8e-40 136.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KFM02676.1 - 3.7e-10 38.7 0.0 4.6e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain COQ9 PF08511.6 KFM02677.1 - 2.1e-33 113.6 0.6 4.5e-33 112.6 0.2 1.7 2 0 0 2 2 2 1 COQ9 Herpes_LMP2 PF07415.6 KFM02677.1 - 0.31 9.5 2.0 0.44 9.0 1.4 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein CIAPIN1 PF05093.8 KFM02678.1 - 3e-25 88.1 16.9 1.7e-22 79.3 10.7 2.6 2 1 0 2 2 2 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Methyltransf_11 PF08241.7 KFM02678.1 - 2.4e-05 24.7 0.0 6.3e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFM02678.1 - 0.00013 21.5 0.0 0.0003 20.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFM02678.1 - 0.00019 21.1 0.0 0.00028 20.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFM02678.1 - 0.0021 18.5 0.0 0.0041 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFM02678.1 - 0.016 15.7 0.0 0.031 14.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain GFO_IDH_MocA PF01408.17 KFM02679.1 - 1e-14 55.0 0.0 3.1e-14 53.5 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 KFM02679.1 - 0.00098 19.5 0.0 0.0027 18.0 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 KFM02679.1 - 0.0033 17.5 0.0 0.0094 16.0 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA_C PF02894.12 KFM02679.1 - 0.016 14.9 0.1 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain XdhC_C PF13478.1 KFM02679.1 - 0.043 14.1 0.0 6.7 7.0 0.0 2.3 2 0 0 2 2 2 0 XdhC Rossmann domain Enkurin PF13864.1 KFM02680.1 - 2.7e-27 94.8 1.4 2.7e-27 94.8 1.0 3.0 3 0 0 3 3 3 1 Calmodulin-binding PB1 PF00564.19 KFM02681.1 - 1.3e-12 47.1 0.3 2.6e-12 46.2 0.0 1.6 2 0 0 2 2 2 1 PB1 domain PDZ PF00595.19 KFM02681.1 - 7.3e-12 45.3 0.3 1.7e-11 44.1 0.2 1.6 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM02681.1 - 0.11 12.4 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 PDZ domain ubiquitin PF00240.18 KFM02682.1 - 0.00096 18.4 0.2 0.0016 17.8 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2428 PF10350.4 KFM02682.1 - 0.084 11.8 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) zf-C4H2 PF10146.4 KFM02682.1 - 0.097 12.6 0.6 0.14 12.1 0.4 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein Lamp PF01299.12 KFM02682.1 - 0.16 11.1 2.6 0.22 10.6 1.8 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Pex14_N PF04695.8 KFM02682.1 - 0.39 10.7 2.6 0.25 11.3 0.1 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region LBP_BPI_CETP_C PF02886.12 KFM02683.1 - 2.9e-27 95.4 0.8 2.9e-27 95.4 0.6 1.8 2 0 0 2 2 2 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.20 KFM02683.1 - 3.8e-26 91.3 1.3 8.5e-26 90.2 0.2 1.9 2 0 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain NACHT PF05729.7 KFM02684.1 - 2.2e-35 121.7 0.1 5.1e-35 120.5 0.1 1.7 1 0 0 1 1 1 1 NACHT domain LRR_6 PF13516.1 KFM02684.1 - 1.6e-32 107.8 54.3 0.00098 18.9 0.5 17.2 17 0 0 17 17 17 7 Leucine Rich repeat LRR_4 PF12799.2 KFM02684.1 - 3.3e-16 58.4 49.0 0.00072 19.1 0.8 12.1 10 4 4 14 14 14 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM02684.1 - 7.2e-15 54.4 46.9 0.0012 18.5 3.1 11.5 7 3 3 11 11 11 7 Leucine rich repeat AAA PF00004.24 KFM02684.1 - 6.1e-06 26.4 0.0 1.7e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LRR_1 PF00560.28 KFM02684.1 - 0.00064 19.4 50.2 9.1 6.7 1.8 14.7 14 3 0 14 14 13 1 Leucine Rich Repeat AAA_25 PF13481.1 KFM02684.1 - 0.0011 18.4 0.1 0.074 12.4 0.1 3.1 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KFM02684.1 - 0.0062 16.6 0.0 0.027 14.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFM02684.1 - 0.0071 16.3 0.0 0.022 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.17 KFM02684.1 - 0.066 13.3 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Kinesin PF00225.18 KFM02684.1 - 0.068 11.8 0.0 0.14 10.8 0.0 1.4 1 0 0 1 1 1 0 Kinesin motor domain Mg_chelatase PF01078.16 KFM02684.1 - 0.086 11.9 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 KFM02684.1 - 0.23 10.5 0.0 0.56 9.2 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 KFM02684.1 - 0.24 11.1 0.0 0.59 9.9 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Copine PF07002.11 KFM02685.1 - 4.7e-60 201.5 0.1 1e-59 200.4 0.0 1.6 2 0 0 2 2 2 1 Copine C2 PF00168.25 KFM02685.1 - 1.1e-27 95.6 0.1 8.9e-13 47.9 0.0 2.5 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.4 KFM02685.1 - 5e-10 39.5 0.0 1.2e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 vWA found in TerF C terminus SPRY PF00622.23 KFM02686.1 - 8.2e-22 77.5 0.4 1.3e-21 76.9 0.2 1.3 1 0 0 1 1 1 1 SPRY domain zf-C3HC4_3 PF13920.1 KFM02686.1 - 7.3e-09 35.1 13.5 7.3e-09 35.1 9.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ARL2_Bind_BART PF11527.3 KFM02687.1 - 1.9e-31 108.3 5.2 2.2e-31 108.1 3.6 1.1 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART DUF1269 PF06897.7 KFM02687.1 - 0.034 14.1 0.1 10 6.2 0.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1269) HIF-1 PF11413.3 KFM02687.1 - 0.094 11.9 1.6 0.25 10.5 1.1 1.7 1 0 0 1 1 1 0 Hypoxia-inducible factor-1 Phi-29_GP3 PF05435.6 KFM02687.1 - 0.14 11.3 2.8 0.18 10.9 2.0 1.2 1 0 0 1 1 1 0 Phi-29 DNA terminal protein GP3 MARVEL PF01284.18 KFM02688.1 - 3.5e-14 52.8 20.8 4.8e-14 52.3 14.4 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF3169 PF11368.3 KFM02688.1 - 0.021 14.0 1.8 0.031 13.4 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Claudin_3 PF06653.6 KFM02688.1 - 0.23 11.1 13.3 0.036 13.7 6.3 1.7 2 0 0 2 2 2 0 Tight junction protein, Claudin-like SUR7 PF06687.7 KFM02688.1 - 2.7 7.4 11.4 1.1 8.7 5.8 1.7 2 0 0 2 2 2 0 SUR7/PalI family CbiQ PF02361.11 KFM02688.1 - 3.5 7.1 11.6 4.3 6.8 8.0 1.1 1 0 0 1 1 1 0 Cobalt transport protein Tic20 PF09685.5 KFM02688.1 - 3.6 7.5 17.0 15 5.5 0.1 2.2 2 0 0 2 2 2 0 Tic20-like protein IL8 PF00048.15 KFM02690.1 - 3.3e-14 52.5 0.1 4e-14 52.3 0.1 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like CLTH PF10607.4 KFM02691.1 - 4.1e-43 146.5 0.5 3.2e-42 143.6 0.4 2.0 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 KFM02691.1 - 5.4e-26 91.1 0.2 1.1e-25 90.1 0.1 1.5 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 KFM02691.1 - 2.8e-05 23.7 0.0 6.7e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 LisH SR-25 PF10500.4 KFM02691.1 - 0.87 9.0 22.6 1.4 8.3 15.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF605 PF04652.11 KFM02691.1 - 5.7 6.2 15.6 8.7 5.6 10.8 1.2 1 0 0 1 1 1 0 Vta1 like DivIC PF04977.10 KFM02692.1 - 0.00019 20.8 14.6 0.26 10.7 3.7 4.3 3 0 0 3 3 3 3 Septum formation initiator DUF3450 PF11932.3 KFM02692.1 - 0.0028 16.9 12.3 0.0064 15.7 3.5 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) DUF904 PF06005.7 KFM02692.1 - 0.0065 16.7 3.0 0.0065 16.7 2.1 3.9 4 0 0 4 4 4 1 Protein of unknown function (DUF904) DUF2353 PF09789.4 KFM02692.1 - 0.12 11.5 21.9 0.25 10.5 11.8 2.9 1 1 2 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) DUF972 PF06156.8 KFM02692.1 - 0.28 11.5 19.4 1.3 9.4 0.2 4.1 4 1 0 4 4 4 0 Protein of unknown function (DUF972) DUF4446 PF14584.1 KFM02692.1 - 1.3 8.8 11.9 0.18 11.6 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) FlaC_arch PF05377.6 KFM02692.1 - 1.8 8.4 8.8 2.9 7.8 0.7 3.6 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) HALZ PF02183.13 KFM02692.1 - 2 8.2 26.1 0.04 13.6 2.5 4.6 4 1 1 5 5 5 0 Homeobox associated leucine zipper Prefoldin PF02996.12 KFM02692.1 - 2.6 7.7 14.0 13 5.4 1.2 3.6 2 0 0 2 2 2 0 Prefoldin subunit V_ATPase_I PF01496.14 KFM02692.1 - 5.7 4.6 18.0 0.045 11.6 3.4 2.4 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Baculo_PEP_C PF04513.7 KFM02692.1 - 6.2 6.6 11.0 0.2 11.4 0.4 3.1 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus FliD_N PF02465.13 KFM02692.1 - 9.4 6.6 12.0 49 4.3 0.0 4.5 4 1 0 4 4 4 0 Flagellar hook-associated protein 2 N-terminus CENP-T PF15511.1 KFM02693.1 - 1.2e-21 77.4 0.2 1.4e-21 77.2 0.2 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 KFM02693.1 - 4.7e-08 33.0 0.0 7e-08 32.5 0.0 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KFM02693.1 - 1.7e-05 24.8 0.1 3e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KFM02693.1 - 0.0041 17.2 0.1 0.0056 16.7 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 KFM02693.1 - 0.019 14.7 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated NTF2 PF02136.15 KFM02694.1 - 3.7e-32 111.1 0.2 4.2e-32 111.0 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain SnoaL_4 PF13577.1 KFM02694.1 - 0.079 12.8 0.0 0.092 12.6 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain DUF4440 PF14534.1 KFM02694.1 - 0.13 12.4 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) WD40 PF00400.27 KFM02695.1 - 0.00025 20.7 0.1 0.005 16.6 0.1 3.1 2 0 0 2 2 2 1 WD domain, G-beta repeat Membr_traf_MHD PF10540.4 KFM02695.1 - 0.17 11.7 6.6 0.94 9.2 0.0 3.5 3 1 0 3 3 3 0 Munc13 (mammalian uncoordinated) homology domain Pkinase PF00069.20 KFM02696.1 - 1.7e-73 247.0 0.0 2.3e-73 246.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM02696.1 - 1.7e-35 122.3 0.0 2.2e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM02696.1 - 3e-07 29.6 0.1 3.4e-05 22.9 0.0 2.5 2 1 1 3 3 3 2 Kinase-like APH PF01636.18 KFM02696.1 - 6.9e-05 22.6 0.0 0.19 11.4 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KFM02696.1 - 0.0052 15.8 0.1 0.011 14.7 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family OHCU_decarbox PF09349.5 KFM02696.1 - 0.11 12.7 1.8 1.5 9.0 1.3 2.3 1 1 0 1 1 1 0 OHCU decarboxylase TmoB PF06234.7 KFM02696.1 - 0.15 11.8 0.4 1.4 8.8 0.0 2.7 3 0 0 3 3 3 0 Toluene-4-monooxygenase system protein B (TmoB) Trypsin PF00089.21 KFM02697.1 - 3.9e-44 150.8 0.4 4.3e-44 150.7 0.3 1.0 1 0 0 1 1 1 1 Trypsin DUF316 PF03761.10 KFM02697.1 - 0.0076 15.6 0.0 0.014 14.7 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF316) Peptidase_C37 PF05416.7 KFM02697.1 - 0.091 11.0 0.2 0.11 10.8 0.1 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase DUF1986 PF09342.6 KFM02697.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Trypsin PF00089.21 KFM02698.1 - 0.025 14.1 0.1 0.029 13.9 0.1 1.1 1 0 0 1 1 1 0 Trypsin Sec6 PF06046.8 KFM02699.1 - 1.2e-124 416.4 1.1 1.2e-124 416.4 0.8 1.6 2 0 0 2 2 2 1 Exocyst complex component Sec6 Sec8_exocyst PF04048.9 KFM02699.1 - 0.011 15.3 0.8 0.076 12.6 0.2 2.5 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain E2F_TDP PF02319.15 KFM02700.1 - 1.1e-14 53.7 0.1 2.1e-14 52.8 0.1 1.5 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain DivIC PF04977.10 KFM02700.1 - 0.046 13.1 0.7 0.075 12.5 0.5 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF3584 PF12128.3 KFM02700.1 - 0.057 10.7 0.3 0.076 10.3 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) XhlA PF10779.4 KFM02700.1 - 0.083 12.8 6.0 0.14 12.0 4.2 1.4 1 0 0 1 1 1 0 Haemolysin XhlA B-block_TFIIIC PF04182.7 KFM02700.1 - 0.09 12.6 0.3 1.1 9.1 0.2 2.2 1 1 0 1 1 1 0 B-block binding subunit of TFIIIC AKAP2_C PF15304.1 KFM02700.1 - 3.2 7.2 9.2 1.1 8.8 0.1 2.1 2 0 0 2 2 2 0 A-kinase anchor protein 2 C-terminus DUF3361 PF11841.3 KFM02701.1 - 3.5e-56 189.3 3.9 3.5e-56 189.3 2.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) ELMO_CED12 PF04727.8 KFM02701.1 - 4.1e-49 166.3 0.6 7.1e-49 165.6 0.4 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family DUF1910 PF08928.5 KFM02701.1 - 0.024 14.6 1.3 8.2 6.4 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1910) DUF1704 PF08014.6 KFM02702.1 - 4.9e-12 45.5 0.0 8.6e-12 44.7 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1704) LCAT PF02450.10 KFM02703.1 - 8.6e-124 413.4 0.8 1e-123 413.2 0.5 1.0 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.2 KFM02703.1 - 2.6e-05 24.2 0.0 5.3e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KFM02703.1 - 0.007 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF915 PF06028.6 KFM02703.1 - 0.01 14.9 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DUF1749 PF08538.5 KFM02703.1 - 0.01 14.7 0.0 0.026 13.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Abhydrolase_5 PF12695.2 KFM02703.1 - 0.011 15.4 0.0 0.025 14.3 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF900 PF05990.7 KFM02703.1 - 0.017 14.4 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Ser_hydrolase PF06821.8 KFM02703.1 - 0.038 13.6 0.0 0.077 12.5 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase DUF676 PF05057.9 KFM02703.1 - 0.075 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) HAD_2 PF13419.1 KFM02703.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase adh_short PF00106.20 KFM02704.1 - 5e-08 33.0 0.0 1e-07 32.0 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase zf-H2C2_2 PF13465.1 KFM02705.1 - 1.1e-54 180.1 93.1 4.3e-08 33.0 2.1 11.3 11 0 0 11 11 11 9 Zinc-finger double domain zf-C2H2 PF00096.21 KFM02705.1 - 2e-31 106.3 104.6 0.00026 21.1 0.7 11.3 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM02705.1 - 2.8e-24 83.6 91.4 0.00093 19.3 2.2 11.3 11 0 0 11 11 11 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM02705.1 - 1.2e-08 34.8 64.5 0.012 15.7 0.3 11.2 9 1 2 11 11 11 5 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 KFM02705.1 - 2.2e-05 24.4 16.0 0.00019 21.4 0.6 10.7 11 1 0 11 11 11 4 C2H2-type zinc-finger domain zf-met PF12874.2 KFM02705.1 - 0.011 15.9 1.5 0.011 15.9 1.1 10.1 11 0 0 11 11 11 0 Zinc-finger of C2H2 type GAGA PF09237.6 KFM02705.1 - 1.4 8.5 31.0 3 7.5 0.0 7.9 1 1 9 10 10 10 0 GAGA factor zf-C2H2_2 PF12756.2 KFM02705.1 - 2.4 8.3 61.1 2.3 8.3 4.8 7.5 1 1 6 7 7 7 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 KFM02705.1 - 4.4 7.3 68.0 0.056 13.3 1.4 10.3 11 1 0 11 11 11 0 C2H2-type zinc finger adh_short PF00106.20 KFM02707.1 - 3e-16 59.7 0.2 6e-16 58.8 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFM02707.1 - 9.2e-05 22.1 0.7 0.0008 19.1 0.5 2.1 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 KFM02708.1 - 2.2e-17 63.4 0.6 4.4e-17 62.4 0.4 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFM02708.1 - 6.2e-09 35.7 0.0 1.3e-08 34.7 0.0 1.4 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KFM02708.1 - 3.2e-06 27.1 0.0 2.2e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KFM02708.1 - 0.055 13.4 0.0 11 5.9 0.0 2.3 2 0 0 2 2 2 0 NADH(P)-binding tRNA-synt_2c PF01411.14 KFM02709.1 - 1.7e-223 742.9 0.0 2.4e-223 742.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 KFM02709.1 - 2.5e-16 59.2 0.1 5.9e-16 58.0 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 KFM02709.1 - 6.8e-09 35.2 0.2 6.1e-08 32.2 0.0 2.5 2 0 0 2 2 2 1 DHHA1 domain GTP_EFTU_D4 PF14578.1 KFM02709.1 - 0.034 13.7 0.0 0.094 12.3 0.0 1.7 1 0 0 1 1 1 0 Elongation factor Tu domain 4 EntA_Immun PF08951.5 KFM02709.1 - 0.044 13.9 2.7 0.29 11.3 0.5 2.5 2 0 0 2 2 2 0 Enterocin A Immunity Lipase_GDSL_3 PF14606.1 KFM02709.1 - 0.044 13.5 0.0 0.091 12.4 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Med11 PF10280.4 KFM02709.1 - 0.053 13.5 0.0 0.24 11.4 0.0 2.0 2 0 0 2 2 2 0 Mediator complex protein ALIX_LYPXL_bnd PF13949.1 KFM02709.1 - 0.15 11.0 3.6 0.26 10.1 2.5 1.3 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Lectin_C PF00059.16 KFM02710.1 - 6.8e-18 65.2 0.2 1.3e-17 64.3 0.2 1.5 1 0 0 1 1 1 1 Lectin C-type domain hEGF PF12661.2 KFM02710.1 - 0.00049 20.0 17.7 0.0097 15.9 6.1 3.3 2 0 0 2 2 2 2 Human growth factor-like EGF Chordopox_A33R PF05966.7 KFM02710.1 - 0.03 13.0 0.0 0.048 12.4 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus A33R protein EGF_CA PF07645.10 KFM02711.1 - 5e-19 68.0 41.1 8.4e-08 32.0 0.5 5.4 5 1 0 5 5 5 4 Calcium-binding EGF domain cEGF PF12662.2 KFM02711.1 - 9.1e-12 44.3 34.9 5.4e-08 32.3 0.1 5.6 5 1 0 5 5 5 3 Complement Clr-like EGF-like EGF PF00008.22 KFM02711.1 - 1.5e-11 43.9 17.8 7.8e-09 35.3 5.3 5.8 5 1 1 6 6 6 2 EGF-like domain FXa_inhibition PF14670.1 KFM02711.1 - 5.1e-09 36.1 43.9 8.9e-07 28.9 2.6 4.9 5 0 0 5 5 5 3 Coagulation Factor Xa inhibitory site Sushi PF00084.15 KFM02711.1 - 5.3e-08 33.0 0.2 5.3e-08 33.0 0.1 4.7 4 1 1 5 5 5 1 Sushi domain (SCR repeat) EGF_2 PF07974.8 KFM02711.1 - 0.0043 17.1 13.4 0.0043 17.1 9.3 5.2 4 0 0 4 4 4 1 EGF-like domain EGF_3 PF12947.2 KFM02711.1 - 0.071 13.0 31.2 0.21 11.5 0.0 5.2 4 1 1 5 5 5 0 EGF domain hEGF PF12661.2 KFM02711.1 - 0.094 12.8 27.8 0.058 13.4 3.4 5.3 5 0 0 5 5 5 0 Human growth factor-like EGF zf-DHHC PF01529.15 KFM02712.1 - 1.9e-31 108.8 7.7 1.9e-31 108.8 5.3 1.7 1 1 0 1 1 1 1 DHHC palmitoyltransferase Picorna_P3A PF06363.6 KFM02712.1 - 0.043 13.8 0.0 0.18 11.8 0.0 2.1 2 0 0 2 2 2 0 Picornaviridae P3A protein DUF4131 PF13567.1 KFM02712.1 - 0.46 9.8 9.9 0.083 12.2 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) p25-alpha PF05517.7 KFM02713.1 - 2.7e-58 196.5 6.5 3.1e-58 196.3 4.5 1.0 1 0 0 1 1 1 1 p25-alpha DnaB PF00772.16 KFM02713.1 - 0.0081 16.0 0.0 0.013 15.3 0.0 1.6 1 1 0 1 1 1 1 DnaB-like helicase N terminal domain BTB_2 PF02214.17 KFM02714.1 - 1.2e-14 54.3 1.3 9.3e-06 25.7 0.0 4.1 4 0 0 4 4 4 3 BTB/POZ domain TAFH PF07531.9 KFM02714.1 - 0.0016 18.0 0.0 0.0039 16.7 0.0 1.6 1 0 0 1 1 1 1 NHR1 homology to TAF RhoGEF PF00621.15 KFM02715.1 - 1.7e-31 109.5 1.3 1.7e-31 109.5 0.9 2.6 2 1 0 2 2 2 1 RhoGEF domain PH PF00169.24 KFM02715.1 - 4.2e-05 23.6 0.1 0.00013 22.1 0.1 1.9 1 0 0 1 1 1 1 PH domain CRAL_TRIO_2 PF13716.1 KFM02715.1 - 4.9e-05 23.2 0.1 0.00098 19.0 0.0 2.9 2 1 0 2 2 2 1 Divergent CRAL/TRIO domain PH_10 PF15411.1 KFM02715.1 - 0.0038 17.3 0.8 0.33 11.1 0.0 2.8 1 1 0 2 2 2 1 Pleckstrin homology domain Na_H_Exchanger PF00999.16 KFM02717.1 - 4.1e-81 272.4 41.2 5.3e-81 272.0 28.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family adh_short PF00106.20 KFM02718.1 - 2.2e-23 82.9 0.0 3.2e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFM02718.1 - 7e-12 45.6 0.0 1.1e-11 45.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFM02718.1 - 0.00081 19.0 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KFM02718.1 - 0.014 15.3 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding vATP-synt_AC39 PF01992.11 KFM02719.1 - 2.3e-101 339.3 0.0 2.5e-101 339.1 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Agouti PF05039.7 KFM02720.1 - 4.3e-29 100.7 6.7 6.1e-29 100.2 4.7 1.3 1 0 0 1 1 1 1 Agouti protein SET PF00856.23 KFM02721.1 - 2.1e-13 50.8 0.0 3.3e-12 46.9 0.0 2.6 2 1 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.6 KFM02721.1 - 6.1e-07 29.3 4.7 6.1e-07 29.3 3.2 1.7 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding YlbD_coat PF14071.1 KFM02721.1 - 0.036 14.1 1.0 0.036 14.1 0.7 2.6 3 0 0 3 3 3 0 Putative coat protein RNA_pol_Rpo13 PF12136.3 KFM02721.1 - 0.11 12.2 0.2 0.11 12.2 0.1 2.8 3 0 0 3 3 3 0 RNA polymerase Rpo13 subunit HTH domain Aa_trans PF01490.13 KFM02722.1 - 2.9e-54 184.1 23.7 3.6e-54 183.8 16.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KFM02722.1 - 4.1e-08 32.4 21.6 9.1e-08 31.3 10.7 2.3 2 0 0 2 2 2 2 Tryptophan/tyrosine permease family Aminotran_1_2 PF00155.16 KFM02723.1 - 4.4e-92 308.8 0.0 5e-92 308.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Mastoparan PF08249.6 KFM02723.1 - 0.4 11.3 1.8 2.2 9.0 1.3 2.2 1 0 0 1 1 1 0 Mastoparan protein EF-hand_1 PF00036.27 KFM02724.1 - 1e-12 46.3 0.0 1.2e-06 27.3 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 KFM02724.1 - 5.9e-11 42.3 0.0 9.1e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 KFM02724.1 - 1.6e-09 36.6 0.1 0.00031 19.9 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KFM02724.1 - 1.6e-09 36.7 0.0 2.2e-05 23.9 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 KFM02724.1 - 1.1e-07 31.3 0.2 1.6e-06 27.5 0.0 2.0 1 1 1 2 2 2 2 EF-hand domain pair PNP_UDP_1 PF01048.15 KFM02725.1 - 3.7e-47 160.2 0.1 4.1e-47 160.1 0.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily FtsJ PF01728.14 KFM02726.1 - 4.9e-27 95.0 0.0 2.3e-26 92.8 0.0 2.1 2 0 0 2 2 2 1 FtsJ-like methyltransferase Vac14_Fig4_bd PF11916.3 KFM02728.1 - 6.2e-78 260.1 8.5 1e-77 259.3 5.9 1.4 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 KFM02728.1 - 1.9e-45 153.1 0.2 3.1e-40 136.4 0.0 4.2 3 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT PF02985.17 KFM02728.1 - 6.5e-09 35.1 0.4 0.0051 16.7 0.0 5.1 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 KFM02728.1 - 2e-07 31.2 0.2 0.1 13.1 0.0 5.1 5 0 0 5 5 5 2 HEAT-like repeat HEAT_2 PF13646.1 KFM02728.1 - 3e-07 30.6 0.0 0.27 11.5 0.0 4.1 3 1 0 3 3 3 2 HEAT repeats Cnd1 PF12717.2 KFM02728.1 - 0.016 15.0 3.1 2.9 7.6 0.0 4.0 4 1 1 6 6 6 0 non-SMC mitotic condensation complex subunit 1 IL34 PF15036.1 KFM02729.1 - 1.8e-37 128.4 1.1 2e-37 128.3 0.8 1.0 1 0 0 1 1 1 1 Interleukin 34 CPSF_A PF03178.10 KFM02730.1 - 6.6e-103 344.1 0.0 4.7e-100 334.8 0.0 2.5 2 0 0 2 2 2 2 CPSF A subunit region MMS1_N PF10433.4 KFM02730.1 - 3.6e-79 266.2 0.0 8.5e-79 264.9 0.0 1.6 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term COG4 PF08318.7 KFM02731.1 - 1.5e-100 336.2 7.6 2.4e-100 335.5 5.3 1.3 1 0 0 1 1 1 1 COG4 transport protein Glyco_transf_29 PF00777.13 KFM02732.1 - 2.8e-72 243.0 0.0 3.3e-72 242.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) DAO PF01266.19 KFM02733.1 - 6.9e-70 235.7 0.0 9.4e-70 235.2 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T PF01571.16 KFM02733.1 - 5.4e-56 189.2 0.0 9.7e-56 188.4 0.0 1.4 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KFM02733.1 - 7.4e-21 73.9 0.0 2.4e-20 72.3 0.0 1.9 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Pyr_redox_3 PF13738.1 KFM02733.1 - 1.1e-07 32.0 0.6 1e-05 25.7 0.4 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFM02733.1 - 2e-07 30.2 0.4 4.3e-07 29.1 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain GMC_oxred_N PF00732.14 KFM02733.1 - 0.00013 21.2 0.2 0.15 11.1 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase Trp_halogenase PF04820.9 KFM02733.1 - 0.00014 20.6 1.0 0.015 13.9 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase FAD_oxidored PF12831.2 KFM02733.1 - 0.0002 20.5 1.2 0.00047 19.3 0.9 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KFM02733.1 - 0.0012 18.7 0.2 0.031 14.1 0.1 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KFM02733.1 - 0.0023 17.0 2.6 0.015 14.4 1.8 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KFM02733.1 - 0.0033 17.4 0.2 0.01 15.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 KFM02733.1 - 0.0036 17.4 0.0 0.023 14.7 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 KFM02733.1 - 0.01 14.9 0.6 0.19 10.8 0.1 2.2 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.9 KFM02733.1 - 0.015 13.8 0.9 0.024 13.1 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.22 KFM02733.1 - 0.028 14.7 1.4 3.8 7.9 0.2 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KFM02733.1 - 0.086 12.8 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Cys_rich_FGFR PF00839.12 KFM02734.1 - 2.4e-210 680.6 118.9 1.9e-19 69.3 1.4 15.3 16 0 0 16 16 16 15 Cysteine rich repeat zf-RING_2 PF13639.1 KFM02735.1 - 1e-10 41.2 2.8 1e-10 41.2 1.9 3.1 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFM02735.1 - 3.9e-09 36.3 2.3 3.9e-09 36.3 1.6 3.3 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM02735.1 - 2.6e-08 33.3 1.2 2.6e-08 33.3 0.9 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFM02735.1 - 2.7e-07 30.5 0.8 2.7e-07 30.5 0.6 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KFM02735.1 - 6.1e-07 29.0 0.8 6.1e-07 29.0 0.6 2.8 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFM02735.1 - 6.8e-05 22.5 0.1 0.00023 20.7 0.1 2.0 1 0 0 1 1 1 1 RING-type zinc-finger WD40 PF00400.27 KFM02735.1 - 0.00044 20.0 1.1 0.38 10.7 0.1 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat Rtf2 PF04641.7 KFM02735.1 - 0.00084 18.6 2.6 0.00084 18.6 1.8 1.6 1 1 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4_4 PF15227.1 KFM02735.1 - 0.0034 17.2 2.3 0.0034 17.2 1.6 2.9 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 KFM02735.1 - 0.012 15.4 2.4 0.068 13.0 1.7 2.4 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KFM02735.1 - 0.016 14.7 3.1 0.016 14.7 2.1 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.1 KFM02735.1 - 0.022 14.5 0.5 0.022 14.5 0.4 2.0 2 0 0 2 2 1 0 Zinc-binding RING-finger FANCL_C PF11793.3 KFM02735.1 - 0.22 11.5 6.5 2.9 7.9 4.5 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain Pkinase_Tyr PF07714.12 KFM02736.1 - 1.6e-43 148.6 0.1 6.5e-41 140.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 KFM02736.1 - 2.3e-32 112.1 0.0 4.7e-32 111.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain FA_hydroxylase PF04116.8 KFM02737.1 - 1.3e-13 51.3 11.5 1.3e-13 51.3 8.0 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.8 KFM02737.1 - 0.066 13.2 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region COX14 PF14880.1 KFM02737.1 - 0.089 12.4 8.9 0.041 13.5 2.6 2.3 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Kua-UEV1_localn PF10520.4 KFM02737.1 - 3.2 7.3 10.2 0.69 9.5 3.1 2.2 2 1 0 2 2 2 0 Kua-ubiquitin conjugating enzyme hybrid localisation domain WD40 PF00400.27 KFM02738.1 - 3.3e-18 64.8 17.6 2.6e-06 27.0 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 KFM02738.1 - 7.9e-05 22.4 0.7 0.13 11.9 0.1 2.6 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A zf-RING_2 PF13639.1 KFM02738.1 - 0.31 10.8 14.3 0.023 14.5 4.4 2.9 2 0 0 2 2 2 0 Ring finger domain zf-rbx1 PF12678.2 KFM02738.1 - 9.1 6.4 16.3 1.4 9.0 7.8 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger CUB PF00431.15 KFM02740.1 - 7.3e-28 96.8 0.0 1e-13 51.2 0.0 2.5 2 0 0 2 2 2 2 CUB domain Ldl_recept_a PF00057.13 KFM02740.1 - 1e-06 28.5 3.9 1e-06 28.5 2.7 2.6 3 0 0 3 3 3 1 Low-density lipoprotein receptor domain class A C1q PF00386.16 KFM02742.1 - 5.9e-24 84.4 0.2 6.5e-24 84.3 0.1 1.0 1 0 0 1 1 1 1 C1q domain SOCS_box PF07525.11 KFM02743.1 - 1.2e-14 53.8 1.7 2.8e-14 52.6 1.1 1.7 1 0 0 1 1 1 1 SOCS box SH2 PF00017.19 KFM02743.1 - 5.3e-13 48.5 0.0 1.5e-12 47.0 0.0 1.8 1 0 0 1 1 1 1 SH2 domain RTTN_N PF14726.1 KFM02744.1 - 1e-26 93.3 6.5 6.5e-26 90.7 0.0 5.3 5 1 1 6 6 6 1 Rotatin, an armadillo repeat protein, centriole functioning V-set PF07686.12 KFM02745.1 - 8.4e-20 70.7 0.5 7.6e-10 38.6 0.1 2.1 2 0 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.1 KFM02745.1 - 4.5e-07 29.8 0.1 0.018 15.1 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 KFM02745.1 - 4.1e-06 26.5 0.5 0.00041 20.1 0.1 2.6 2 1 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.20 KFM02745.1 - 5.6e-05 23.1 0.5 0.17 12.0 0.0 3.3 3 1 0 3 3 3 2 Immunoglobulin domain IRS PF02174.12 KFM02746.1 - 2e-29 101.1 0.0 3.6e-29 100.3 0.0 1.4 1 0 0 1 1 1 1 PTB domain (IRS-1 type) PH PF00169.24 KFM02746.1 - 0.00062 19.9 0.5 0.0015 18.7 0.3 1.6 1 0 0 1 1 1 1 PH domain Thioredoxin PF00085.15 KFM02747.1 - 6.2e-27 93.3 0.0 1.4e-25 88.9 0.0 2.7 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_6 PF13848.1 KFM02747.1 - 6.6e-26 91.2 0.1 2.9e-23 82.6 0.3 2.2 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 KFM02747.1 - 3.3e-07 30.5 0.1 9.1e-06 25.8 0.0 3.2 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KFM02747.1 - 0.00012 22.0 0.3 0.055 13.5 0.0 3.7 3 1 1 4 4 4 1 Thioredoxin-like Thioredoxin_7 PF13899.1 KFM02747.1 - 0.023 14.6 0.2 0.087 12.8 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like SH3_5 PF08460.5 KFM02747.1 - 0.084 12.8 0.2 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain Transglut_C PF00927.17 KFM02748.1 - 8.4e-30 102.9 0.0 1.1e-15 57.5 0.0 2.7 3 0 0 3 3 3 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.14 KFM02748.1 - 1.1e-11 44.9 0.1 2.3e-11 43.8 0.1 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Leu_zip PF15294.1 KFM02749.1 - 0.0044 16.1 29.3 0.0044 16.1 20.3 3.6 1 1 2 3 3 3 1 Leucine zipper Reo_sigmaC PF04582.7 KFM02749.1 - 0.36 9.9 15.7 1.2 8.2 0.6 4.2 2 1 1 4 4 4 0 Reovirus sigma C capsid protein DUF3584 PF12128.3 KFM02749.1 - 0.4 7.9 71.2 0.036 11.4 34.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) CagE_TrbE_VirB PF03135.9 KFM02749.1 - 1.3 8.6 8.0 0.26 11.0 1.7 2.5 2 0 0 2 2 2 0 CagE, TrbE, VirB family, component of type IV transporter system zf-RING_2 PF13639.1 KFM02750.1 - 2.2e-10 40.1 5.8 3.9e-10 39.3 4.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KFM02750.1 - 7e-07 29.2 3.2 1.2e-06 28.5 2.2 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KFM02750.1 - 7.5e-05 22.3 5.9 0.00013 21.5 4.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KFM02750.1 - 0.00038 20.0 5.2 0.0008 19.0 3.6 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM02750.1 - 0.00049 19.7 5.7 0.0012 18.4 3.8 1.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFM02750.1 - 0.0079 16.0 4.9 0.024 14.4 3.5 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 KFM02750.1 - 0.049 13.6 9.8 0.16 11.9 6.7 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Di19 PF05605.7 KFM02750.1 - 0.051 13.6 1.8 0.28 11.3 0.1 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_UBOX PF13445.1 KFM02750.1 - 0.064 12.9 2.1 0.12 12.1 1.5 1.5 1 0 0 1 1 1 0 RING-type zinc-finger DZR PF12773.2 KFM02750.1 - 0.089 12.6 2.4 0.21 11.4 1.6 1.6 1 1 0 1 1 1 0 Double zinc ribbon FANCL_C PF11793.3 KFM02750.1 - 0.13 12.2 8.2 2.6 8.0 5.7 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain Cys_rich_CPXG PF14255.1 KFM02750.1 - 0.2 11.5 2.4 4.7 7.0 0.1 2.3 2 0 0 2 2 2 0 Cysteine-rich CPXCG zf-UDP PF14569.1 KFM02750.1 - 0.28 10.9 2.1 0.53 10.0 1.4 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger Neur_chan_LBD PF02931.18 KFM02751.1 - 1.5e-67 226.8 0.1 1.9e-67 226.6 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFM02751.1 - 2.9e-40 138.6 0.1 5.4e-39 134.4 0.1 2.0 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Nup96 PF12110.3 KFM02752.1 - 1.3e-90 303.4 0.1 1.8e-90 302.9 0.1 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 KFM02752.1 - 1.8e-45 154.2 0.0 2.9e-45 153.5 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 KFM02752.1 - 1.1e-05 25.6 227.5 0.23 11.6 34.0 5.8 2 2 3 5 5 5 3 Nucleoporin FG repeat region Frag1 PF10277.4 KFM02753.1 - 2.5e-12 46.7 6.0 2.7e-12 46.6 4.1 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Ras PF00071.17 KFM02754.1 - 1.6e-55 186.9 0.0 1.8e-55 186.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM02754.1 - 1.7e-15 57.5 0.0 2.6e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM02754.1 - 2.2e-10 40.0 0.0 3.1e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFM02754.1 - 0.0061 15.7 0.0 0.0092 15.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SAM_2 PF07647.12 KFM02755.1 - 8.3e-09 35.1 0.3 4.6e-08 32.8 0.0 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFM02755.1 - 1.4e-05 25.2 1.1 3.8e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Ste50p-SAM PF09235.5 KFM02755.1 - 0.031 14.2 0.0 0.073 13.1 0.0 1.7 1 0 0 1 1 1 0 Ste50p, sterile alpha motif DUF4446 PF14584.1 KFM02755.1 - 0.035 13.9 0.7 0.035 13.9 0.5 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) APG6 PF04111.7 KFM02755.1 - 1 8.3 19.9 2.1 7.2 13.8 1.6 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF572 PF04502.8 KFM02755.1 - 4.2 6.4 16.6 5.9 6.0 11.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DivIVA PF05103.8 KFM02755.1 - 7.1 6.6 23.7 2.8 8.0 2.0 2.8 2 1 0 2 2 2 0 DivIVA protein DUF1043 PF06295.7 KFM02755.1 - 9.1 5.9 12.5 1.5 8.4 2.9 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1043) SNF PF00209.13 KFM02756.1 - 2.6e-121 405.6 13.6 3.2e-121 405.3 9.4 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Ribonuc_red_lgC PF02867.10 KFM02757.1 - 6.8e-196 651.9 0.0 7.7e-159 529.6 0.0 2.1 2 0 0 2 2 2 2 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 KFM02757.1 - 1e-22 79.7 0.0 2.7e-22 78.3 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 KFM02757.1 - 1.5e-13 50.9 0.1 5.5e-13 49.1 0.0 2.1 2 0 0 2 2 2 1 ATP cone domain 7tm_4 PF13853.1 KFM02758.1 - 4.3e-23 81.7 7.1 4.3e-23 81.7 4.9 2.1 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFM02758.1 - 2.5e-21 75.9 17.5 3.1e-21 75.6 12.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM02758.1 - 2.3e-07 30.2 12.1 2.3e-07 30.2 8.4 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.1 KFM02759.1 - 1.3e-19 70.4 10.4 1.3e-19 70.4 7.2 2.3 2 1 1 3 3 3 1 Olfactory receptor 7tm_1 PF00001.16 KFM02759.1 - 2.2e-12 46.6 22.4 1.7e-11 43.7 15.5 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM02759.1 - 4.1e-05 22.8 8.5 4.1e-05 22.8 5.9 2.2 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx Clp1 PF06807.9 KFM02760.1 - 2.5e-51 174.2 0.0 3.7e-51 173.6 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 KFM02760.1 - 1.6e-21 76.4 0.0 4.2e-21 75.1 0.0 1.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 KFM02760.1 - 0.0055 16.2 0.2 0.012 15.2 0.0 1.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 KFM02760.1 - 0.013 16.2 0.2 0.038 14.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KFM02760.1 - 0.029 13.8 0.0 0.051 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.1 KFM02760.1 - 0.047 13.8 0.0 0.099 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 KFM02760.1 - 0.062 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 KFM02760.1 - 0.079 12.4 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 KFM02760.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase Sigma54_activat PF00158.21 KFM02760.1 - 0.13 11.7 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.1 KFM02760.1 - 0.13 12.5 0.0 0.45 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain zf-DHHC PF01529.15 KFM02761.1 - 2.1e-33 115.1 4.1 6.4e-33 113.5 2.9 1.8 1 1 0 1 1 1 1 DHHC palmitoyltransferase zf-CXXC PF02008.15 KFM02761.1 - 0.13 12.0 3.9 0.25 11.1 2.7 1.4 1 0 0 1 1 1 0 CXXC zinc finger domain O-antigen_lig PF13425.1 KFM02761.1 - 0.5 10.3 6.2 2.8 7.9 2.2 2.2 2 0 0 2 2 2 0 O-antigen ligase like membrane protein mono-CXXC PF15626.1 KFM02761.1 - 6.3 6.8 10.2 0.17 11.8 1.7 2.4 2 0 0 2 2 2 0 single CXXC unit Med19 PF10278.4 KFM02762.1 - 1.9e-79 265.5 13.6 2.1e-79 265.3 9.5 1.0 1 0 0 1 1 1 1 Mediator of RNA pol II transcription subunit 19 RR_TM4-6 PF06459.7 KFM02762.1 - 0.003 17.4 3.3 0.0031 17.4 2.3 1.1 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 Zip PF02535.17 KFM02762.1 - 0.025 13.5 2.7 0.027 13.4 1.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RNA_polI_A34 PF08208.6 KFM02762.1 - 0.26 10.9 23.6 0.37 10.4 16.3 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Tim54 PF11711.3 KFM02762.1 - 0.75 8.3 7.8 0.95 7.9 5.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Herpes_DNAp_acc PF04929.7 KFM02762.1 - 0.99 8.2 10.4 1.1 8.1 7.2 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Thioredoxin PF00085.15 KFM02763.1 - 3e-11 42.8 0.0 5.8e-11 42.0 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KFM02763.1 - 0.048 13.7 0.1 0.19 11.8 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin-like Arm PF00514.18 KFM02764.1 - 6.1e-34 114.6 4.4 2.4e-07 30.3 0.0 7.2 7 0 0 7 7 7 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFM02764.1 - 7.7e-07 29.3 3.0 0.01 16.0 0.0 3.6 4 0 0 4 4 4 2 HEAT repeats Arm_2 PF04826.8 KFM02764.1 - 0.00012 21.2 0.0 0.58 9.2 0.0 2.8 2 1 0 2 2 2 2 Armadillo-like HEAT PF02985.17 KFM02764.1 - 0.00019 21.2 1.1 4 7.7 0.1 4.5 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 KFM02764.1 - 0.00037 20.8 0.6 3 8.4 0.1 4.6 5 0 0 5 5 5 1 HEAT-like repeat Atx10homo_assoc PF09759.4 KFM02764.1 - 0.049 13.3 2.0 4.2 7.1 0.0 3.7 4 0 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain zf-C2H2 PF00096.21 KFM02765.1 - 1.2e-16 59.9 33.1 0.00082 19.5 0.5 5.4 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM02765.1 - 1.1e-14 53.9 23.6 9e-05 22.5 0.2 4.5 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM02765.1 - 7.1e-09 35.3 30.8 0.0076 16.5 0.8 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KFM02765.1 - 0.00028 20.4 11.5 0.14 11.8 0.2 4.5 4 0 0 4 4 4 2 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.5 KFM02765.1 - 0.0051 16.7 11.2 0.19 11.6 0.1 3.7 3 1 0 3 3 3 2 Zinc ribbon domain Prok-RING_1 PF14446.1 KFM02765.1 - 0.15 11.7 0.1 0.15 11.7 0.1 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-C2H2_jaz PF12171.3 KFM02765.1 - 0.6 10.3 14.8 0.13 12.4 0.6 3.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 KFM02765.1 - 3.3 7.9 23.8 0.4 10.8 3.7 3.8 3 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_2 PF13639.1 KFM02766.1 - 2e-09 37.1 2.2 5.1e-09 35.8 1.5 1.7 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KFM02766.1 - 4.2e-08 33.1 0.9 7.9e-08 32.3 0.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KFM02766.1 - 6.7e-08 32.0 1.4 1.5e-07 30.9 1.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM02766.1 - 2.2e-05 24.1 1.6 5.1e-05 22.8 1.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KFM02766.1 - 0.00017 21.3 1.4 0.00039 20.1 1.0 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 KFM02766.1 - 0.00031 20.6 5.5 0.0022 17.9 0.5 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFM02766.1 - 0.00097 18.8 1.4 0.0053 16.4 1.0 2.3 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 KFM02766.1 - 0.001 18.7 2.8 0.0025 17.4 1.2 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFM02766.1 - 0.0016 18.2 3.4 0.0067 16.2 0.8 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING PHD PF00628.24 KFM02766.1 - 0.034 13.8 0.3 0.034 13.8 0.2 2.0 2 0 0 2 2 2 0 PHD-finger zf-RING_4 PF14570.1 KFM02766.1 - 0.039 13.5 1.4 0.058 12.9 0.1 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.1 KFM02766.1 - 0.057 13.1 0.1 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger FANCL_C PF11793.3 KFM02766.1 - 0.082 12.8 1.6 0.28 11.1 1.1 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain Trm112p PF03966.11 KFM02766.1 - 0.089 13.1 0.1 0.17 12.2 0.1 1.6 1 0 0 1 1 1 0 Trm112p-like protein zf-Nse PF11789.3 KFM02766.1 - 0.1 12.1 1.2 0.21 11.1 0.8 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zinc_ribbon_5 PF13719.1 KFM02766.1 - 0.11 12.0 0.7 3 7.5 0.0 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Prok-RING_1 PF14446.1 KFM02766.1 - 0.4 10.4 3.6 7 6.4 0.0 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 MACPF PF01823.14 KFM02767.1 - 2.1e-25 89.6 0.0 3.3e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 MAC/Perforin domain RVT_1 PF00078.22 KFM02769.1 - 0.0055 16.0 0.0 0.0085 15.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-HC5HC2H_2 PF13832.1 KFM02771.1 - 2e-39 133.9 4.5 2e-39 133.9 3.1 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.4 KFM02771.1 - 8.5e-36 123.6 2.4 8.5e-36 123.6 1.7 2.7 3 0 0 3 3 3 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.1 KFM02771.1 - 2.4e-27 94.9 3.2 2.4e-27 94.9 2.2 3.5 3 0 0 3 3 3 1 PHD-like zinc-binding domain Bromodomain PF00439.20 KFM02771.1 - 9e-25 86.4 0.4 2.6e-24 84.9 0.3 1.9 1 0 0 1 1 1 1 Bromodomain PWWP PF00855.12 KFM02771.1 - 1.2e-14 54.2 0.0 4.8e-14 52.3 0.0 2.1 1 0 0 1 1 1 1 PWWP domain PHD_2 PF13831.1 KFM02771.1 - 1.8e-13 49.5 4.3 1.8e-13 49.5 3.0 2.9 2 1 0 2 2 2 1 PHD-finger PHD PF00628.24 KFM02771.1 - 7.6e-07 28.7 28.2 1.1e-05 25.0 9.5 2.9 2 0 0 2 2 2 2 PHD-finger DNA_topoisoIV PF00521.15 KFM02771.1 - 0.051 12.4 4.8 0.094 11.5 3.3 1.4 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A zf-BED PF02892.10 KFM02773.1 - 2.6e-59 196.7 27.1 1.6e-15 56.5 0.2 4.5 4 0 0 4 4 4 4 BED zinc finger Dimer_Tnp_hAT PF05699.9 KFM02773.1 - 1.3e-10 40.7 3.6 4.6e-10 38.9 0.4 3.2 3 0 0 3 3 3 1 hAT family C-terminal dimerisation region PyrI_C PF02748.10 KFM02773.1 - 0.013 14.9 5.5 6.1 6.3 0.0 4.0 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF4413 PF14372.1 KFM02773.1 - 0.06 13.3 1.2 0.15 12.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4413) Glyco_transf_22 PF03901.12 KFM02774.1 - 2.4e-43 148.7 29.8 3e-43 148.4 20.6 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family EGF_CA PF07645.10 KFM02775.1 - 4.4e-14 52.1 31.3 2.9e-11 43.1 7.6 7.2 4 2 2 6 6 6 2 Calcium-binding EGF domain DUF3456 PF11938.3 KFM02775.1 - 4.4e-11 43.0 6.1 1.8e-06 28.0 2.0 3.1 2 1 1 3 3 3 2 TLR4 regulator and MIR-interacting MSAP cEGF PF12662.2 KFM02775.1 - 0.00079 19.0 10.1 0.0017 17.9 1.2 6.1 6 1 0 6 6 6 2 Complement Clr-like EGF-like VSP PF03302.8 KFM02775.1 - 0.0018 16.9 60.4 0.067 11.8 20.3 2.9 1 1 1 2 2 2 2 Giardia variant-specific surface protein EGF PF00008.22 KFM02775.1 - 0.0038 17.1 2.2 0.0038 17.1 1.6 6.3 7 2 1 8 8 8 3 EGF-like domain PmrD PF11183.3 KFM02775.1 - 0.022 14.5 0.4 0.052 13.3 0.3 1.7 1 0 0 1 1 1 0 Polymyxin resistance protein PmrD EGF_MSP1_1 PF12946.2 KFM02775.1 - 0.026 14.3 4.4 0.026 14.3 3.0 4.9 4 1 1 5 5 5 0 MSP1 EGF domain 1 hEGF PF12661.2 KFM02775.1 - 2.4 8.4 19.5 0.4 10.8 0.9 6.0 6 1 0 6 6 6 0 Human growth factor-like EGF PrmA PF06325.8 KFM02777.1 - 3.3e-09 36.2 0.0 5.5e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 KFM02777.1 - 1.2e-07 31.4 0.1 2.2e-07 30.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 KFM02777.1 - 8.9e-07 28.1 0.3 1.1e-06 27.8 0.2 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_18 PF12847.2 KFM02777.1 - 8.9e-07 29.4 0.0 1.7e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFM02777.1 - 1.6e-06 28.1 0.0 2.5e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFM02777.1 - 5.8e-06 26.7 0.0 1.3e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 KFM02777.1 - 2.6e-05 23.8 0.1 4.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.1 KFM02777.1 - 9.6e-05 22.1 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFM02777.1 - 0.0001 21.7 0.1 0.00017 20.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DOT1 PF08123.8 KFM02777.1 - 0.0011 18.3 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_9 PF08003.6 KFM02777.1 - 0.003 16.3 0.0 0.0043 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.7 KFM02777.1 - 0.0057 17.1 0.0 0.01 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KFM02777.1 - 0.0073 15.7 0.1 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.14 KFM02777.1 - 0.013 15.0 0.2 0.029 13.9 0.0 1.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 KFM02777.1 - 0.026 13.5 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.12 KFM02777.1 - 0.029 13.4 0.0 0.048 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_25 PF13649.1 KFM02777.1 - 0.081 13.2 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PNRC PF15365.1 KFM02777.1 - 0.095 12.7 1.9 0.2 11.6 1.3 1.5 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator Ras PF00071.17 KFM02778.1 - 2.2e-44 150.7 0.1 2.4e-44 150.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM02778.1 - 7.4e-22 78.0 0.0 8.6e-22 77.8 0.0 1.0 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM02778.1 - 4.5e-17 61.8 0.1 5.8e-17 61.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFM02778.1 - 3.4e-09 36.6 0.1 4.2e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFM02778.1 - 1.2e-07 31.1 0.0 1.4e-07 30.9 0.0 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KFM02778.1 - 3.1e-05 23.2 0.0 3.8e-05 22.9 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 KFM02778.1 - 0.00012 21.5 0.0 0.00053 19.4 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KFM02778.1 - 0.003 17.3 0.0 0.017 14.9 0.0 1.9 1 1 1 2 2 2 1 Dynamin family AAA PF00004.24 KFM02778.1 - 0.012 15.7 0.0 0.019 15.1 0.0 1.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KFM02778.1 - 0.03 14.1 0.0 0.033 14.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KFM02778.1 - 0.031 14.4 0.0 0.048 13.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KFM02778.1 - 0.035 14.9 0.0 0.039 14.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 KFM02778.1 - 0.037 13.5 0.1 1.2 8.5 0.0 2.1 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 KFM02778.1 - 0.039 13.2 0.1 0.053 12.8 0.0 1.5 1 1 0 1 1 1 0 Ferrous iron transport protein B G-alpha PF00503.15 KFM02778.1 - 0.041 12.5 0.6 5.2 5.6 0.1 2.5 1 1 1 2 2 2 0 G-protein alpha subunit Septin PF00735.13 KFM02778.1 - 0.09 11.7 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Septin EIIA-man PF03610.11 KFM02778.1 - 0.094 12.7 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 PTS system fructose IIA component MobB PF03205.9 KFM02778.1 - 0.099 12.3 0.0 0.19 11.4 0.0 1.4 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B OKR_DC_1_N PF03709.10 KFM02778.1 - 0.12 12.4 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain EF-hand_7 PF13499.1 KFM02779.1 - 1.8e-10 40.7 0.9 5.6e-07 29.5 0.1 3.0 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.1 KFM02779.1 - 1.7e-08 33.6 1.1 0.0071 16.1 0.1 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 KFM02779.1 - 4.3e-08 31.8 3.8 0.00045 19.3 0.1 3.2 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 KFM02779.1 - 2.2e-07 30.3 3.0 6.6e-07 28.8 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.1 KFM02779.1 - 3.8e-06 25.9 0.1 0.038 13.3 0.0 3.1 2 0 0 2 2 2 2 EF hand LMP PF04778.7 KFM02779.1 - 0.0084 15.8 7.5 0.015 15.0 4.8 1.7 1 1 0 1 1 1 1 LMP repeated region TroA PF01297.12 KFM02779.1 - 0.027 13.7 0.1 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 Periplasmic solute binding protein family SpoIIAA-like PF11964.3 KFM02779.1 - 0.046 13.9 0.1 2.4 8.4 0.0 2.6 2 0 0 2 2 2 0 SpoIIAA-like FTCD_C PF04961.7 KFM02779.1 - 0.2 11.0 4.2 0.46 9.8 2.9 1.6 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase HSP70 PF00012.15 KFM02779.1 - 0.46 8.3 7.3 0.53 8.1 5.0 1.3 1 0 0 1 1 1 0 Hsp70 protein DUF4584 PF15223.1 KFM02779.1 - 1.5 7.9 6.3 2.4 7.3 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4584) Tup_N PF08581.5 KFM02779.1 - 6.4 7.0 24.4 1.9 8.7 3.9 2.8 1 1 1 2 2 2 0 Tup N-terminal Tetraspannin PF00335.15 KFM02782.1 - 1.3e-48 165.2 12.7 1.4e-48 165.0 8.8 1.0 1 0 0 1 1 1 1 Tetraspanin family Claudin_2 PF13903.1 KFM02782.1 - 0.00018 21.2 2.0 0.0084 15.8 1.1 2.2 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction ODV-E18 PF10717.4 KFM02782.1 - 0.14 11.5 1.2 0.27 10.6 0.2 1.9 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Baculo_11_kDa PF06143.6 KFM02782.1 - 0.31 10.4 3.4 0.19 11.0 0.5 1.9 2 0 0 2 2 2 0 Baculovirus 11 kDa family 5TM-5TMR_LYT PF07694.7 KFM02782.1 - 0.65 9.3 9.2 3.3 7.0 2.7 2.1 2 0 0 2 2 2 0 5TMR of 5TMR-LYT TEA PF01285.13 KFM02783.1 - 1.1e-176 588.2 0.1 1.4e-176 587.9 0.1 1.0 1 0 0 1 1 1 1 TEA/ATTS domain family Myb_DNA-binding PF00249.26 KFM02783.1 - 0.087 12.8 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Tub PF01167.13 KFM02784.1 - 9.7e-117 388.2 0.0 1.3e-116 387.8 0.0 1.2 1 0 0 1 1 1 1 Tub family RHINO PF15319.1 KFM02785.1 - 5.4e-75 252.2 10.6 6.1e-75 252.0 7.4 1.0 1 0 0 1 1 1 1 RAD9, RAD1, HUS1-interacting nuclear orphan protein Fork_head PF00250.13 KFM02786.1 - 1.5e-27 95.4 0.2 3.3e-27 94.3 0.1 1.5 1 0 0 1 1 1 1 Fork head domain Asp_protease PF09668.5 KFM02787.1 - 1.4e-09 37.6 0.0 2e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KFM02787.1 - 0.0015 18.2 0.0 0.0053 16.5 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 KFM02787.1 - 0.13 12.7 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease BBS2_Mid PF14783.1 KFM02788.1 - 2.1e-12 46.7 0.3 0.00065 19.4 0.0 3.5 3 0 0 3 3 3 3 Ciliary BBSome complex subunit 2, middle region VCBS PF13517.1 KFM02788.1 - 0.00013 22.2 1.4 0.25 11.7 0.1 3.7 3 0 0 3 3 3 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 KFM02788.1 - 0.00021 20.8 1.0 0.88 9.3 0.0 3.8 3 0 0 3 3 3 2 FG-GAP repeat BBS2_C PF14782.1 KFM02788.1 - 0.044 12.3 0.0 10 4.5 0.0 2.9 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, C-terminal DUF4399 PF14347.1 KFM02788.1 - 0.049 13.6 0.1 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4399) FKBP_C PF00254.23 KFM02789.1 - 6.8e-48 160.6 0.0 6.1e-31 106.3 0.0 2.4 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_11 PF13414.1 KFM02789.1 - 3.2e-19 68.3 4.4 3.7e-14 52.1 1.2 2.6 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KFM02789.1 - 1.5e-18 65.5 10.4 2.2e-09 36.5 1.4 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFM02789.1 - 3.8e-15 54.5 12.1 2.9e-06 26.7 0.9 4.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFM02789.1 - 4.8e-09 35.3 7.2 3.8e-05 23.1 0.6 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFM02789.1 - 1.6e-08 35.0 0.5 0.0078 16.8 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFM02789.1 - 2.8e-08 33.6 1.1 0.011 16.1 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFM02789.1 - 1.9e-06 27.6 11.8 0.00017 21.4 1.0 3.1 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFM02789.1 - 2.2e-06 27.8 5.5 0.0005 20.3 1.5 2.9 3 1 0 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFM02789.1 - 5.2e-06 26.6 0.1 0.018 15.6 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFM02789.1 - 6.7e-05 22.3 4.1 0.033 13.9 0.2 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KFM02789.1 - 0.00044 20.0 0.3 0.00044 20.0 0.2 3.1 3 1 1 4 4 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.1 KFM02789.1 - 0.0022 17.8 0.0 0.0066 16.2 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFM02789.1 - 0.0049 16.9 5.9 0.059 13.5 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF3856 PF12968.2 KFM02789.1 - 0.0056 16.5 0.3 0.011 15.5 0.2 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF3856) Apc3 PF12895.2 KFM02789.1 - 0.018 15.1 7.4 0.06 13.4 4.3 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.4 KFM02789.1 - 1.5 8.7 6.4 0.36 10.7 0.9 2.4 2 1 1 3 3 3 0 Tetratricopeptide repeat M60-like PF13402.1 KFM02790.1 - 1e-88 297.2 0.0 1.4e-88 296.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase M60-like family ThuA PF06283.6 KFM02790.1 - 1.1e-05 25.2 0.3 6 6.5 0.0 4.3 4 0 0 4 4 4 3 Trehalose utilisation Lact_bio_phlase PF09508.5 KFM02790.1 - 0.0009 17.0 0.0 0.18 9.4 0.0 2.7 3 0 0 3 3 3 2 Lacto-N-biose phosphorylase TCRP1 PF14944.1 KFM02790.1 - 0.12 12.2 0.1 0.2 11.5 0.1 1.2 1 0 0 1 1 1 0 Tongue Cancer Chemotherapy Resistant Protein 1 Lectin_C PF00059.16 KFM02791.1 - 9.8e-15 55.0 0.6 1.3e-14 54.7 0.1 1.4 1 1 0 1 1 1 1 Lectin C-type domain Herpes_UL45 PF05473.7 KFM02791.1 - 0.066 12.6 0.1 0.081 12.3 0.1 1.1 1 0 0 1 1 1 0 UL45 protein Lectin_C PF00059.16 KFM02792.1 - 6.5e-13 49.2 1.0 7.9e-13 48.9 0.2 1.4 1 1 0 1 1 1 1 Lectin C-type domain Herpes_UL45 PF05473.7 KFM02792.1 - 0.072 12.5 0.3 0.082 12.3 0.2 1.1 1 0 0 1 1 1 0 UL45 protein Lectin_C PF00059.16 KFM02793.1 - 9.8e-15 55.0 0.6 1.3e-14 54.7 0.1 1.4 1 1 0 1 1 1 1 Lectin C-type domain Herpes_UL45 PF05473.7 KFM02793.1 - 0.066 12.6 0.1 0.081 12.3 0.1 1.1 1 0 0 1 1 1 0 UL45 protein DUF1681 PF07933.9 KFM02794.1 - 1.6e-55 187.0 0.0 2e-55 186.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Imm49 PF15660.1 KFM02794.1 - 0.16 12.0 0.2 0.29 11.2 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 49 Sugar_tr PF00083.19 KFM02795.1 - 1.5e-158 528.0 29.2 1.7e-158 527.9 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFM02795.1 - 2.4e-21 75.8 31.9 1.2e-19 70.2 18.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFM02795.1 - 1e-05 24.1 37.3 0.00055 18.4 7.7 3.4 1 1 2 3 3 3 2 MFS/sugar transport protein Phage_holin_2 PF04550.7 KFM02795.1 - 4.9 7.3 11.8 0.16 12.0 2.5 2.8 2 1 2 4 4 4 0 Phage holin family 2 Homeobox PF00046.24 KFM02796.1 - 3.8e-22 77.6 6.1 4.7e-22 77.3 3.5 1.6 2 0 0 2 2 2 1 Homeobox domain Homez PF11569.3 KFM02796.1 - 9.9e-06 24.5 0.5 1.7e-05 23.7 0.3 1.3 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.6 KFM02796.1 - 0.0014 18.3 0.1 0.0034 17.0 0.1 1.7 1 1 0 1 1 1 1 Homeobox KN domain Pro-kuma_activ PF09286.6 KFM02796.1 - 0.0017 18.4 0.2 0.0022 18.0 0.1 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Antimicrobial21 PF14861.1 KFM02796.1 - 0.045 13.2 4.4 0.078 12.4 3.1 1.4 1 0 0 1 1 1 0 Plant antimicrobial peptide Cortex-I_coil PF09304.5 KFM02796.1 - 0.11 12.5 0.7 0.15 12.1 0.5 1.2 1 0 0 1 1 1 0 Cortexillin I, coiled coil HTH_23 PF13384.1 KFM02796.1 - 0.13 11.9 0.1 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Homeobox PF00046.24 KFM02797.1 - 1.7e-21 75.5 5.1 2.9e-21 74.8 3.5 1.4 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 KFM02797.1 - 0.0001 21.3 0.4 0.0002 20.3 0.3 1.5 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Pro-kuma_activ PF09286.6 KFM02797.1 - 0.00078 19.5 0.3 0.0017 18.4 0.2 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Homeobox_KN PF05920.6 KFM02797.1 - 0.00082 19.0 0.0 0.0026 17.4 0.0 1.9 1 0 0 1 1 1 1 Homeobox KN domain 2Fe-2S_thioredx PF01257.14 KFM02797.1 - 0.11 12.0 0.2 0.2 11.2 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin APOBEC_N PF08210.6 KFM02798.1 - 7.1e-19 68.1 0.1 7.6e-19 68.0 0.1 1.0 1 0 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC_N PF08210.6 KFM02799.1 - 1.8e-23 83.1 0.1 2e-23 83.0 0.0 1.0 1 0 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC_C PF05240.9 KFM02799.1 - 1.6e-09 37.0 0.9 2.2e-09 36.5 0.0 1.7 2 0 0 2 2 2 1 APOBEC-like C-terminal domain dCMP_cyt_deam_1 PF00383.17 KFM02799.1 - 4.2e-05 23.1 0.0 5.3e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Toxin-deaminase PF14424.1 KFM02799.1 - 0.14 12.1 0.1 0.21 11.5 0.1 1.2 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases APOBEC_N PF08210.6 KFM02800.1 - 3.2e-48 163.8 0.2 3.7e-48 163.6 0.2 1.0 1 0 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC_C PF05240.9 KFM02800.1 - 1e-22 79.2 0.1 2.1e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 APOBEC-like C-terminal domain Toxin-deaminase PF14424.1 KFM02800.1 - 0.058 13.3 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases RcbX PF02341.10 KFM02800.1 - 0.11 12.6 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 RbcX protein MAGP PF05507.6 KFM02801.1 - 1.2e-28 99.6 9.0 1.2e-28 99.6 6.2 1.5 2 0 0 2 2 2 1 Microfibril-associated glycoprotein (MAGP) SVWC PF15430.1 KFM02801.1 - 1.2 9.6 4.6 0.82 10.1 0.4 2.3 1 1 1 2 2 2 0 Single domain von Willebrand factor type C PAP2 PF01569.16 KFM02802.1 - 1.6e-15 56.8 1.0 3.2e-15 55.9 0.7 1.5 1 0 0 1 1 1 1 PAP2 superfamily Ribosomal_L50 PF10501.4 KFM02803.1 - 2.2e-22 79.1 0.3 3e-22 78.7 0.0 1.3 2 0 0 2 2 2 1 Ribosomal subunit 39S Glycolytic PF00274.14 KFM02804.1 - 8.1e-173 573.6 0.0 9.1e-173 573.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Glyco_transf_54 PF04666.8 KFM02805.1 - 0.0025 16.5 0.0 0.12 11.1 0.0 2.4 3 0 0 3 3 3 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region zf-C3HC4_3 PF13920.1 KFM02806.1 - 8.3e-06 25.3 11.6 1.4e-05 24.6 8.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM02806.1 - 5.9e-05 22.6 14.6 0.00011 21.7 10.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM02806.1 - 0.00017 21.5 14.4 0.00029 20.8 10.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM02806.1 - 0.00077 19.1 13.7 0.0036 17.0 9.9 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 KFM02806.1 - 0.021 14.6 14.5 0.078 12.8 10.3 1.8 1 1 1 2 2 2 0 Ring finger domain zf-RING_6 PF14835.1 KFM02806.1 - 0.063 13.0 2.8 0.13 12.0 1.9 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 KFM02806.1 - 0.47 10.2 8.3 1.4 8.6 5.8 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-Apc11 PF12861.2 KFM02806.1 - 0.49 10.2 4.8 0.9 9.4 3.4 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 KFM02806.1 - 0.6 10.0 9.5 1.4 8.8 6.6 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Lig_chan PF00060.21 KFM02807.1 - 4.2e-29 101.1 0.3 1e-28 99.9 0.0 1.8 2 0 0 2 2 2 1 Ligand-gated ion channel SBP_bac_3 PF00497.15 KFM02807.1 - 1e-22 80.5 0.0 1.7e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.4 KFM02807.1 - 1.5e-19 69.6 0.8 5.3e-19 67.9 0.6 2.0 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site ORMDL PF04061.9 KFM02808.1 - 8.4e-35 119.2 0.3 9.3e-35 119.1 0.2 1.0 1 0 0 1 1 1 1 ORMDL family Peptidase_M22 PF00814.20 KFM02809.1 - 2.8e-56 190.9 1.0 3.3e-56 190.7 0.7 1.1 1 0 0 1 1 1 1 Glycoprotease family Asn_synthase PF00733.16 KFM02811.1 - 5.3e-64 216.1 0.0 7e-64 215.7 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KFM02811.1 - 6e-07 29.2 0.0 4.1e-06 26.5 0.0 2.3 2 1 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KFM02811.1 - 0.0026 17.7 0.0 0.016 15.1 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase domain ATP_bind_3 PF01171.15 KFM02811.1 - 0.01 15.3 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 PP-loop family QueC PF06508.8 KFM02811.1 - 0.021 14.1 0.0 0.049 12.9 0.0 1.6 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 KFM02811.1 - 0.11 11.0 0.0 0.2 10.1 0.0 1.4 1 0 0 1 1 1 0 tRNA methyl transferase NAD_synthase PF02540.12 KFM02811.1 - 0.12 11.2 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 NAD synthase FPN1 PF06963.7 KFM02812.1 - 2.5e-182 606.1 13.9 2.8e-182 605.9 9.6 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) MFS_1 PF07690.11 KFM02812.1 - 5.2e-06 25.4 31.0 1.1e-05 24.2 1.3 3.7 3 1 1 4 4 4 3 Major Facilitator Superfamily DUF347 PF03988.7 KFM02812.1 - 0.12 12.3 0.1 0.12 12.3 0.1 4.0 3 2 1 4 4 4 0 Repeat of Unknown Function (DUF347) WD40 PF00400.27 KFM02813.1 - 2.9e-19 68.1 16.7 7e-05 22.5 0.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat COLFI PF01410.13 KFM02814.1 - 4.4e-52 176.5 0.0 4.8e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Collagen PF01391.13 KFM02815.1 - 5.7e-116 378.0 565.2 3.8e-09 35.9 23.7 16.9 3 2 8 11 11 11 7 Collagen triple helix repeat (20 copies) COLFI PF01410.13 KFM02815.1 - 3.1e-95 317.6 0.0 3.9e-95 317.2 0.0 1.1 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain PID PF00640.18 KFM02816.1 - 2.4e-33 115.0 0.4 3.6e-33 114.5 0.2 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.8 KFM02816.1 - 9.2e-12 45.0 0.3 1.6e-11 44.1 0.2 1.4 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PID_2 PF14719.1 KFM02816.1 - 2.4e-05 24.0 0.1 3.3e-05 23.6 0.0 1.3 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) DUF3373 PF11853.3 KFM02816.1 - 0.00098 17.7 0.2 0.0014 17.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3373) DivIC PF04977.10 KFM02816.1 - 0.0012 18.2 4.6 0.0022 17.4 3.2 1.3 1 0 0 1 1 1 1 Septum formation initiator bZIP_2 PF07716.10 KFM02816.1 - 0.0014 18.4 4.8 0.003 17.3 3.3 1.5 1 0 0 1 1 1 1 Basic region leucine zipper TSC22 PF01166.13 KFM02816.1 - 0.0037 17.1 1.2 0.0098 15.8 0.8 1.7 1 0 0 1 1 1 1 TSC-22/dip/bun family Ax_dynein_light PF10211.4 KFM02816.1 - 0.0037 17.1 0.3 0.0063 16.3 0.2 1.3 1 0 0 1 1 1 1 Axonemal dynein light chain Herpes_BLRF2 PF05812.7 KFM02816.1 - 0.0088 15.8 1.3 0.019 14.8 0.1 1.9 2 0 0 2 2 2 1 Herpesvirus BLRF2 protein bZIP_1 PF00170.16 KFM02816.1 - 0.0095 15.8 1.7 0.016 15.1 1.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor Spc24 PF08286.6 KFM02816.1 - 0.01 15.5 0.3 0.021 14.5 0.2 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 ATG16 PF08614.6 KFM02816.1 - 0.011 15.5 1.3 0.018 14.8 0.9 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4200 PF13863.1 KFM02816.1 - 0.016 15.1 1.1 0.022 14.6 0.1 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) Leu_zip PF15294.1 KFM02816.1 - 0.017 14.2 0.8 0.027 13.5 0.5 1.2 1 0 0 1 1 1 0 Leucine zipper DUF972 PF06156.8 KFM02816.1 - 0.02 15.2 0.1 0.044 14.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Striatin PF08232.7 KFM02816.1 - 0.025 14.8 0.0 0.053 13.8 0.0 1.5 1 0 0 1 1 1 0 Striatin family Herpes_UL6 PF01763.11 KFM02816.1 - 0.026 12.7 0.0 0.041 12.0 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like ORF6C PF10552.4 KFM02816.1 - 0.03 14.0 0.6 0.073 12.8 0.4 1.6 1 0 0 1 1 1 0 ORF6C domain IncA PF04156.9 KFM02816.1 - 0.031 13.8 0.4 0.043 13.4 0.3 1.3 1 0 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 KFM02816.1 - 0.035 13.9 5.0 0.086 12.6 3.5 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Nnf1 PF03980.9 KFM02816.1 - 0.043 13.8 3.0 0.043 13.8 2.1 1.6 2 0 0 2 2 1 0 Nnf1 Med4 PF10018.4 KFM02816.1 - 0.045 13.1 0.2 0.094 12.1 0.1 1.5 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Prefoldin_2 PF01920.15 KFM02816.1 - 0.062 13.0 2.8 0.13 12.0 1.9 1.5 1 0 0 1 1 1 0 Prefoldin subunit DUF904 PF06005.7 KFM02816.1 - 0.068 13.4 3.6 0.14 12.4 2.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Pox_A_type_inc PF04508.7 KFM02816.1 - 0.36 10.7 2.3 0.74 9.7 0.3 2.3 1 1 1 2 2 2 0 Viral A-type inclusion protein repeat DUF4315 PF14193.1 KFM02816.1 - 1.6 8.7 5.4 0.54 10.2 1.6 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4315) M PF02370.11 KFM02816.1 - 9.2 7.0 6.7 6.9 7.4 2.5 2.5 2 1 1 3 3 2 0 M protein repeat Kunitz_BPTI PF00014.18 KFM02818.1 - 2.6e-54 181.2 40.6 2.2e-19 69.3 3.9 3.2 3 0 0 3 3 3 3 Kunitz/Bovine pancreatic trypsin inhibitor domain Toxin_2 PF00451.14 KFM02818.1 - 0.24 11.4 7.9 4.7 7.3 0.6 4.0 3 0 0 3 3 3 0 Scorpion short toxin, BmKK2 Defensin_3 PF08131.6 KFM02818.1 - 1.4 8.9 7.2 4.2 7.4 0.1 3.9 3 1 0 3 3 3 0 Defensin-like peptide family WW PF00397.21 KFM02818.1 - 1.5 8.7 4.0 9.3 6.2 0.1 3.0 3 0 0 3 3 3 0 WW domain 7tm_2 PF00002.19 KFM02819.1 - 7.1e-78 261.0 19.3 9.2e-78 260.6 13.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 KFM02819.1 - 3.7e-17 62.1 8.1 7.1e-17 61.1 5.6 1.5 1 0 0 1 1 1 1 Hormone receptor domain C2 PF00168.25 KFM02820.1 - 4.4e-09 36.0 0.1 6.2e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 C2 domain Anillin PF08174.6 KFM02820.1 - 0.099 12.6 0.1 0.14 12.2 0.0 1.4 1 1 0 1 1 1 0 Cell division protein anillin Actin PF00022.14 KFM02821.1 - 1.3e-87 293.8 0.0 3.4e-87 292.4 0.0 1.6 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KFM02821.1 - 2.7e-05 22.9 0.0 0.043 12.4 0.0 2.3 2 1 0 2 2 2 2 MreB/Mbl protein Robl_LC7 PF03259.12 KFM02821.1 - 0.015 14.8 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 Roadblock/LC7 domain DPPIV_N PF00930.16 KFM02822.1 - 1.9e-110 368.7 0.2 2.7e-110 368.3 0.2 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 KFM02822.1 - 2.7e-49 167.3 0.0 4e-49 166.7 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KFM02822.1 - 1.6e-06 27.9 0.0 2.8e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KFM02822.1 - 5.7e-05 22.5 0.2 0.0003 20.1 0.1 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family PD40 PF07676.7 KFM02822.1 - 0.00012 21.6 0.0 1.1 8.9 0.0 3.4 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Abhydrolase_6 PF12697.2 KFM02822.1 - 0.00028 20.8 0.0 0.0034 17.2 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KFM02822.1 - 0.0015 17.9 2.1 0.0017 17.7 0.2 2.0 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 KFM02822.1 - 0.006 16.1 0.0 0.065 12.7 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Yae1_N PF09811.4 KFM02823.1 - 0.0083 15.6 10.5 0.0083 15.6 7.3 4.5 2 2 0 2 2 2 1 Essential protein Yae1, N terminal DEAD PF00270.24 KFM02824.1 - 4.6e-45 153.1 0.0 1e-44 151.9 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFM02824.1 - 1.5e-21 76.0 0.0 4.5e-21 74.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 KFM02824.1 - 6.9e-20 70.3 0.4 1.3e-19 69.4 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 KFM02824.1 - 6.9e-06 26.0 0.7 1.3e-05 25.1 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CENP-B_dimeris PF09026.5 KFM02824.1 - 0.068 13.4 4.9 0.17 12.1 3.4 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain 7tm_1 PF00001.16 KFM02825.1 - 1.5e-74 250.4 9.3 2e-74 249.9 6.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM02825.1 - 2.2e-05 23.7 5.5 3.9e-05 22.9 3.2 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx PgaD PF13994.1 KFM02825.1 - 0.0097 15.3 0.0 0.0097 15.3 0.0 2.8 2 1 0 3 3 3 1 PgaD-like protein 7TM_GPCR_Srx PF10328.4 KFM02825.1 - 0.22 10.5 8.8 0.0093 15.0 1.5 2.1 2 2 1 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srx DUF3278 PF11683.3 KFM02825.1 - 0.91 9.5 3.8 2 8.4 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3278) IclR PF01614.13 KFM02826.1 - 0.031 13.9 0.2 0.049 13.3 0.2 1.3 1 0 0 1 1 1 0 Bacterial transcriptional regulator MBOAT_2 PF13813.1 KFM02826.1 - 0.16 12.0 4.7 0.062 13.3 1.3 1.8 1 1 0 2 2 2 0 Membrane bound O-acyl transferase family ACC_epsilon PF13822.1 KFM02826.1 - 5 7.5 6.8 3.4 8.0 0.8 2.1 1 1 1 2 2 2 0 Acyl-CoA carboxylase epsilon subunit KOG2701 PF09762.4 KFM02827.1 - 2.7e-81 271.9 0.1 2.7e-81 271.9 0.1 3.8 2 1 1 4 4 4 1 Coiled-coil domain-containing protein (DUF2037) Reo_sigmaC PF04582.7 KFM02827.1 - 0.1 11.7 6.4 0.025 13.7 1.9 1.8 2 0 0 2 2 2 0 Reovirus sigma C capsid protein PMC2NT PF08066.7 KFM02827.1 - 0.43 10.9 13.3 5.1 7.4 1.2 4.0 3 1 0 3 3 3 0 PMC2NT (NUC016) domain Baculo_PEP_C PF04513.7 KFM02827.1 - 0.43 10.3 11.9 3.3 7.5 4.8 3.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus INSIG PF07281.7 KFM02828.1 - 1e-56 191.3 0.7 1.1e-56 191.2 0.5 1.0 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) OMP_b-brl PF13505.1 KFM02828.1 - 0.025 14.5 0.1 0.032 14.1 0.0 1.1 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain Homeobox PF00046.24 KFM02829.1 - 1.1e-22 79.4 8.0 1.7e-22 78.8 5.5 1.3 1 0 0 1 1 1 1 Homeobox domain Engrail_1_C_sig PF10525.4 KFM02829.1 - 2.7e-20 71.1 0.5 4.5e-20 70.4 0.3 1.4 1 0 0 1 1 1 1 Engrailed homeobox C-terminal signature domain DUF2316 PF10078.4 KFM02829.1 - 0.00042 20.2 1.2 0.00061 19.7 0.8 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2316) Homeobox_KN PF05920.6 KFM02829.1 - 0.0022 17.6 1.2 0.0042 16.7 0.6 1.7 1 1 0 1 1 1 1 Homeobox KN domain TPD52 PF04201.10 KFM02829.1 - 0.016 14.9 0.6 0.021 14.5 0.4 1.2 1 0 0 1 1 1 0 Tumour protein D52 family CENP-B_N PF04218.8 KFM02829.1 - 0.018 14.4 1.8 0.022 14.1 0.2 1.9 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain Spc7 PF08317.6 KFM02829.1 - 0.045 12.3 4.5 0.049 12.2 3.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Thiolase_N PF00108.18 KFM02829.1 - 0.05 12.5 0.3 0.077 11.9 0.2 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain OmpH PF03938.9 KFM02829.1 - 0.33 10.8 6.6 0.36 10.7 4.6 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) QLQ PF08880.6 KFM02829.1 - 1 8.8 4.0 0.31 10.4 0.9 1.7 2 1 0 2 2 2 0 QLQ Collagen PF01391.13 KFM02830.1 - 3.7e-40 135.2 128.6 8.8e-10 37.9 18.9 5.3 1 1 2 3 3 3 2 Collagen triple helix repeat (20 copies) SRCR PF00530.13 KFM02830.1 - 1.7e-30 105.2 2.1 3.1e-30 104.4 1.5 1.4 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 KFM02830.1 - 9.8e-07 28.9 0.0 2.3e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain MHC2-interact PF09307.5 KFM02830.1 - 0.0017 18.0 0.0 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 CLIP, MHC2 interacting C1q PF00386.16 KFM02831.1 - 1e-12 48.1 0.1 1.1e-12 48.1 0.0 1.0 1 0 0 1 1 1 1 C1q domain TNF PF00229.13 KFM02831.1 - 0.0067 15.9 0.0 0.0072 15.8 0.0 1.0 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family Ferric_reduct PF01794.14 KFM02832.1 - 1.6e-19 70.2 5.0 4e-16 59.2 1.3 2.3 1 1 1 2 2 2 2 Ferric reductase like transmembrane component F420_oxidored PF03807.12 KFM02832.1 - 5.4e-15 55.6 0.1 3.4e-14 53.0 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 KFM02832.1 - 0.00069 19.4 0.1 0.0034 17.2 0.0 1.9 1 1 1 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.1 KFM02832.1 - 0.0082 16.1 0.1 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding IlvN PF07991.7 KFM02832.1 - 0.0092 15.3 0.0 0.016 14.5 0.0 1.5 1 1 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain DUF781 PF05612.7 KFM02832.1 - 0.048 12.3 0.2 0.18 10.4 0.0 2.0 2 0 0 2 2 2 0 Mouse protein of unknown function (DUF781) 2-Hacid_dh_C PF02826.14 KFM02832.1 - 0.078 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF2340 PF10209.4 KFM02833.1 - 1.6e-45 154.1 0.0 1.8e-45 154.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) TMEM37 PF15108.1 KFM02834.1 - 7e-91 302.9 12.2 7.8e-91 302.7 8.5 1.0 1 0 0 1 1 1 1 Voltage-dependent calcium channel gamma-like subunit protein family SK_channel PF03530.9 KFM02834.1 - 0.11 12.3 2.7 0.56 10.0 0.4 2.2 2 0 0 2 2 2 0 Calcium-activated SK potassium channel Ninjurin PF04923.7 KFM02834.1 - 0.37 10.5 2.0 2.2 8.0 0.0 2.2 2 1 0 2 2 2 0 Ninjurin 7tm_2 PF00002.19 KFM02835.1 - 9.3e-86 286.8 16.7 1.2e-85 286.5 11.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 KFM02835.1 - 2.5e-19 69.0 4.3 5.7e-19 67.8 3.0 1.6 1 0 0 1 1 1 1 Hormone receptor domain PapD-like PF14874.1 KFM02836.1 - 5.4e-06 26.2 0.0 9.2e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Flagellar-associated PapD-like C2 PF00168.25 KFM02838.1 - 3.2e-47 158.2 1.7 1e-18 66.9 0.0 3.4 3 0 0 3 3 3 3 C2 domain Glyco_hydro_77 PF02446.12 KFM02839.1 - 4 5.8 14.7 7.5 5.0 10.2 1.4 1 0 0 1 1 1 0 4-alpha-glucanotransferase FAIM1 PF06905.8 KFM02840.1 - 8e-93 308.5 3.8 9.5e-93 308.2 2.7 1.0 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) 5_nucleotid_C PF02872.13 KFM02840.1 - 0.014 15.4 0.1 0.058 13.3 0.0 1.8 1 1 0 2 2 2 0 5'-nucleotidase, C-terminal domain Macro PF01661.16 KFM02841.1 - 2e-39 134.1 0.3 6.9e-29 100.1 0.0 2.9 3 0 0 3 3 3 2 Macro domain PARP PF00644.15 KFM02841.1 - 4.1e-06 26.3 0.2 2.5e-05 23.7 0.1 2.2 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.15 KFM02844.1 - 5.9e-08 32.0 1.4 5.7e-07 28.8 0.0 2.8 3 1 0 3 3 3 1 WWE domain LSM PF01423.17 KFM02844.1 - 0.0057 16.1 0.5 0.32 10.5 0.1 2.6 2 0 0 2 2 2 1 LSM domain YqgF PF14639.1 KFM02844.1 - 0.014 14.9 0.5 0.037 13.6 0.1 1.8 1 1 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 CIA30 PF08547.7 KFM02844.1 - 0.06 13.2 0.2 0.09 12.6 0.1 1.3 1 0 0 1 1 1 0 Complex I intermediate-associated protein 30 (CIA30) DUF2857 PF11198.3 KFM02844.1 - 1.5 8.2 5.1 4.4 6.7 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2857) Peptidase_M8 PF01457.11 KFM02845.1 - 1.5e-76 257.8 2.4 5.1e-51 173.5 0.0 2.1 1 1 1 2 2 2 2 Leishmanolysin NAD_Gly3P_dh_C PF07479.9 KFM02846.1 - 3.8e-56 188.9 0.2 6.6e-56 188.1 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 KFM02846.1 - 5.4e-47 159.4 0.0 1.4e-46 158.1 0.0 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Oxysterol_BP PF01237.13 KFM02847.1 - 2.1e-70 237.0 0.2 1.9e-69 233.8 0.2 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein PH PF00169.24 KFM02847.1 - 5.4e-12 45.8 0.0 1.2e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 KFM02847.1 - 9.9e-09 35.1 0.0 2.4e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.1 KFM02847.1 - 2.8e-05 24.1 0.0 6.3e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.1 KFM02847.1 - 0.0045 17.1 0.1 0.014 15.5 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PX PF00787.19 KFM02848.1 - 7.1e-23 80.5 0.1 1.7e-22 79.3 0.1 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 KFM02848.1 - 3.3e-07 29.8 12.5 0.00056 19.2 4.0 2.2 1 1 1 2 2 2 2 Vps5 C terminal like DUF4200 PF13863.1 KFM02848.1 - 10 6.1 14.4 7.8 6.4 0.3 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4200) zf-H2C2_2 PF13465.1 KFM02850.1 - 2.7e-24 84.2 22.8 1.2e-07 31.6 0.2 4.6 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.21 KFM02850.1 - 2.2e-13 49.6 37.8 0.00062 19.9 2.7 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM02850.1 - 4.1e-08 33.0 34.2 0.031 14.6 3.3 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger Zn_Tnp_IS1595 PF12760.2 KFM02850.1 - 0.17 11.7 13.7 0.25 11.1 1.9 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DZR PF12773.2 KFM02850.1 - 0.35 10.7 8.0 1.4 8.8 0.5 2.5 2 0 0 2 2 2 0 Double zinc ribbon zf-C2H2_jaz PF12171.3 KFM02850.1 - 0.42 10.8 16.8 3.8 7.7 0.5 3.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding AA_permease PF00324.16 KFM02851.1 - 4.2e-45 154.0 37.4 4.2e-45 154.0 25.9 2.0 2 0 0 2 2 2 1 Amino acid permease AA_permease_2 PF13520.1 KFM02851.1 - 9.8e-20 70.4 36.2 9.8e-20 70.4 25.1 2.1 2 0 0 2 2 2 1 Amino acid permease EGF_CA PF07645.10 KFM02852.1 - 1.1e-08 34.8 29.9 3.4e-08 33.3 2.9 4.2 2 1 2 4 4 4 2 Calcium-binding EGF domain EGF_3 PF12947.2 KFM02852.1 - 7.9e-05 22.5 20.0 0.00088 19.1 2.5 3.4 2 1 1 3 3 3 2 EGF domain EGF PF00008.22 KFM02852.1 - 9.8e-05 22.2 9.1 9.8e-05 22.2 6.3 3.5 3 0 0 3 3 3 1 EGF-like domain EGF_MSP1_1 PF12946.2 KFM02852.1 - 0.00015 21.4 6.5 0.00015 21.4 4.5 3.5 2 1 1 3 3 3 1 MSP1 EGF domain 1 Orthoreo_P10 PF07204.6 KFM02852.1 - 0.012 15.3 0.2 0.026 14.2 0.1 1.5 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 hEGF PF12661.2 KFM02852.1 - 0.041 13.9 7.7 2 8.6 0.4 3.7 3 0 0 3 3 3 0 Human growth factor-like EGF FXa_inhibition PF14670.1 KFM02852.1 - 0.36 10.9 32.0 0.093 12.8 7.5 4.1 2 1 1 3 3 3 0 Coagulation Factor Xa inhibitory site cEGF PF12662.2 KFM02852.1 - 1.1 9.0 23.6 0.54 9.9 1.3 4.9 5 0 0 5 5 5 0 Complement Clr-like EGF-like EB PF01683.13 KFM02852.1 - 1.2 9.2 28.1 1.2 9.2 6.0 3.6 2 1 1 3 3 3 0 EB module CS PF04969.11 KFM02853.1 - 1.3e-16 60.9 1.3 2.4e-16 60.0 0.2 2.1 2 0 0 2 2 2 1 CS domain DUF2360 PF10152.4 KFM02853.1 - 3.3 7.9 6.6 7.6 6.8 4.6 1.7 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) PHO4 PF01384.15 KFM02854.1 - 6.5e-130 432.5 2.6 8.1e-130 432.2 1.8 1.1 1 0 0 1 1 1 1 Phosphate transporter family DUF3855 PF12967.2 KFM02854.1 - 0.067 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3855) CKAP2_C PF15297.1 KFM02855.1 - 6.9e-67 225.7 3.4 9.7e-43 146.3 1.2 2.0 2 0 0 2 2 2 2 Cytoskeleton-associated protein 2 C-terminus MOZART1 PF12554.3 KFM02855.1 - 0.027 13.9 0.3 0.07 12.5 0.2 1.7 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated IL1 PF00340.14 KFM02856.1 - 3.8e-23 81.2 0.0 5.7e-23 80.6 0.0 1.2 1 0 0 1 1 1 1 Interleukin-1 / 18 IL1_propep PF02394.11 KFM02856.1 - 2.9e-18 66.2 0.0 5.5e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Interleukin-1 propeptide DUF480 PF04337.7 KFM02856.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF480 E1_dh PF00676.15 KFM02857.1 - 2.3e-92 308.9 0.0 3.1e-92 308.5 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.19 KFM02857.1 - 1.2e-67 226.8 0.0 1.9e-67 226.2 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DUF4343 PF14243.1 KFM02857.1 - 0.091 12.6 0.1 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4343) RVT_1 PF00078.22 KFM02858.1 - 0.033 13.5 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Pro_isomerase PF00160.16 KFM02859.1 - 4.3e-44 150.4 0.2 4.7e-44 150.3 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD LRR_8 PF13855.1 KFM02860.1 - 5.8e-28 96.4 15.4 5.6e-11 42.0 0.8 3.7 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KFM02860.1 - 5.9e-18 64.0 14.8 2.4e-05 23.8 1.8 4.6 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) I-set PF07679.11 KFM02860.1 - 5.2e-16 58.2 0.0 8.9e-16 57.5 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_5 PF13306.1 KFM02860.1 - 7.8e-13 48.2 0.9 1.7e-06 27.7 0.0 2.3 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) LRR_1 PF00560.28 KFM02860.1 - 1.1e-11 43.0 18.4 0.12 12.4 0.7 7.7 8 0 0 8 8 8 5 Leucine Rich Repeat Ig_2 PF13895.1 KFM02860.1 - 4.6e-11 42.6 0.0 9.8e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFM02860.1 - 2.7e-09 37.3 0.3 8.7e-09 35.7 0.2 1.9 1 0 0 1 1 1 1 Immunoglobulin domain fn3 PF00041.16 KFM02860.1 - 1.8e-06 27.9 0.0 4.3e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain ig PF00047.20 KFM02860.1 - 9.6e-06 25.6 0.1 2.2e-05 24.4 0.1 1.7 1 0 0 1 1 1 1 Immunoglobulin domain LRR_9 PF14580.1 KFM02860.1 - 0.0018 17.8 2.6 0.02 14.4 0.6 2.4 1 1 1 2 2 2 1 Leucine-rich repeat V-set PF07686.12 KFM02860.1 - 0.0034 17.2 0.1 0.014 15.2 0.1 2.0 1 1 0 1 1 1 1 Immunoglobulin V-set domain LRR_7 PF13504.1 KFM02860.1 - 0.034 14.2 19.7 6.7 7.3 0.2 7.5 8 0 0 8 8 8 0 Leucine rich repeat LRR_6 PF13516.1 KFM02860.1 - 0.57 10.4 21.6 2.8 8.2 0.7 6.0 7 0 0 7 7 7 0 Leucine Rich repeat LRR_3 PF07725.7 KFM02860.1 - 8.2 6.4 7.7 29 4.6 0.0 4.5 5 0 0 5 5 5 0 Leucine Rich Repeat RhoGAP PF00620.22 KFM02861.1 - 2.5e-41 140.8 0.3 2.4e-40 137.6 0.1 2.4 2 0 0 2 2 2 1 RhoGAP domain PH_11 PF15413.1 KFM02861.1 - 1.2 9.4 7.0 1.8 8.8 0.1 3.4 3 2 0 3 3 3 0 Pleckstrin homology domain OmpH PF03938.9 KFM02861.1 - 1.4 8.8 8.8 4.9 7.0 6.2 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) LRR_8 PF13855.1 KFM02863.1 - 3e-17 62.0 15.9 5.4e-12 45.2 3.0 2.7 1 1 1 2 2 2 2 Leucine rich repeat 7tm_2 PF00002.19 KFM02863.1 - 5.8e-14 51.7 4.8 1e-13 50.9 3.3 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.16 KFM02863.1 - 5.8e-09 35.9 3.5 1.6e-08 34.4 0.0 3.3 3 0 0 3 3 3 1 Latrophilin/CL-1-like GPS domain I-set PF07679.11 KFM02863.1 - 1.8e-06 27.7 0.0 4.6e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_4 PF12799.2 KFM02863.1 - 1.1e-05 24.9 8.0 0.00034 20.1 1.0 2.7 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) HRM PF02793.17 KFM02863.1 - 0.00026 20.9 0.8 0.00068 19.5 0.5 1.7 1 0 0 1 1 1 1 Hormone receptor domain LRR_1 PF00560.28 KFM02863.1 - 0.0017 18.1 8.0 0.58 10.3 0.2 4.0 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_9 PF14580.1 KFM02863.1 - 0.2 11.2 0.6 0.44 10.0 0.4 1.6 1 0 0 1 1 1 0 Leucine-rich repeat PalH PF08733.5 KFM02863.1 - 0.26 10.0 9.0 0.49 9.1 6.2 1.3 1 0 0 1 1 1 0 PalH/RIM21 LRR_6 PF13516.1 KFM02863.1 - 1.7 8.9 5.2 5.8 7.3 0.3 3.2 2 0 0 2 2 2 0 Leucine Rich repeat RRM_1 PF00076.17 KFM02865.1 - 1.7e-06 27.5 0.0 3.4e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM02865.1 - 3.5e-05 23.7 0.0 7.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM02865.1 - 0.001 18.8 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sod_Cu PF00080.15 KFM02866.1 - 4.4e-32 111.1 0.0 5e-32 111.0 0.0 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DUF2353 PF09789.4 KFM02867.1 - 5e-90 301.9 22.3 6.6e-90 301.6 15.5 1.1 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) DUF869 PF05911.6 KFM02867.1 - 0.0009 17.6 5.8 0.0009 17.6 4.1 2.7 1 1 2 3 3 3 2 Plant protein of unknown function (DUF869) THP2 PF09432.5 KFM02867.1 - 0.0032 17.3 5.1 0.0094 15.8 3.5 1.7 1 0 0 1 1 1 1 Tho complex subunit THP2 KLRAQ PF10205.4 KFM02867.1 - 0.014 15.3 16.9 0.088 12.8 4.8 3.8 2 1 1 3 3 3 0 Predicted coiled-coil domain-containing protein DivIVA PF05103.8 KFM02867.1 - 0.12 12.4 19.5 0.29 11.1 3.8 3.2 2 1 0 2 2 2 0 DivIVA protein OEP PF02321.13 KFM02867.1 - 0.12 11.9 10.9 0.3 10.6 7.5 1.7 1 0 0 1 1 1 0 Outer membrane efflux protein TSC22 PF01166.13 KFM02867.1 - 0.19 11.7 0.1 0.19 11.7 0.1 5.0 5 0 0 5 5 5 0 TSC-22/dip/bun family Mnd1 PF03962.10 KFM02867.1 - 0.22 11.1 21.7 0.33 10.6 3.4 3.0 2 1 0 3 3 3 0 Mnd1 family Ufd2P_core PF10408.4 KFM02867.1 - 0.24 9.5 7.5 0.052 11.7 2.6 1.6 1 1 1 2 2 2 0 Ubiquitin elongating factor core GAS PF13851.1 KFM02867.1 - 0.52 9.4 29.6 3.1 6.9 8.4 3.3 2 2 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4140 PF13600.1 KFM02867.1 - 0.92 9.9 24.7 4.2 7.8 1.1 5.2 5 0 0 5 5 5 0 N-terminal domain of unknown function (DUF4140) Myb_DNA-bind_5 PF13873.1 KFM02867.1 - 1.8 8.5 7.2 4.8 7.1 0.2 3.3 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain DUF4164 PF13747.1 KFM02867.1 - 1.8 8.7 19.1 3.1 7.9 4.2 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4164) COG2 PF06148.6 KFM02867.1 - 1.9 8.3 15.0 0.9 9.4 1.1 3.3 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4482 PF14818.1 KFM02867.1 - 3.2 8.3 24.2 2.8 8.6 2.6 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4482) CorA PF01544.13 KFM02867.1 - 3.4 6.6 16.5 0.2 10.6 5.5 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF342 PF03961.8 KFM02867.1 - 3.5 5.9 19.4 0.2 10.0 2.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF342) CENP-F_leu_zip PF10473.4 KFM02867.1 - 3.6 7.4 31.2 2.6 7.8 11.3 4.2 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rho_Binding PF08912.6 KFM02867.1 - 3.9 7.8 26.0 0.46 10.8 1.0 5.0 5 1 0 5 5 5 0 Rho Binding Phlebovirus_NSM PF07246.6 KFM02867.1 - 4.3 6.4 11.3 4.7 6.2 0.5 2.8 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M Cep57_MT_bd PF06657.8 KFM02867.1 - 4.8 7.1 19.2 0.84 9.6 0.3 4.6 4 1 1 5 5 5 0 Centrosome microtubule-binding domain of Cep57 IncA PF04156.9 KFM02867.1 - 7.3 6.1 38.2 0.017 14.6 10.1 3.6 2 1 0 3 3 3 0 IncA protein EPTP PF03736.12 KFM02868.1 - 3.3e-93 305.2 23.3 6.8e-15 54.5 0.1 7.2 7 0 0 7 7 7 7 EPTP domain LRR_8 PF13855.1 KFM02868.1 - 2.1e-27 94.6 16.5 7.9e-16 57.5 2.2 2.6 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KFM02868.1 - 1.4e-11 43.7 2.6 1.4e-05 24.5 0.1 2.8 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM02868.1 - 4.9e-10 38.0 5.0 0.22 11.6 0.1 5.2 4 0 0 4 4 4 4 Leucine Rich Repeat LRR_5 PF13306.1 KFM02868.1 - 3.1e-06 26.8 0.3 1.3e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_7 PF13504.1 KFM02868.1 - 0.0012 18.6 4.3 1.7 9.2 0.1 4.6 4 0 0 4 4 4 1 Leucine rich repeat LRR_9 PF14580.1 KFM02868.1 - 0.092 12.3 0.1 0.22 11.0 0.1 1.6 1 1 1 2 2 2 0 Leucine-rich repeat LRR_6 PF13516.1 KFM02868.1 - 3.4 8.0 7.5 92 3.5 0.0 4.5 3 1 1 4 4 4 0 Leucine Rich repeat SLA_LP_auto_ag PF05889.8 KFM02869.1 - 4.5e-178 591.6 0.0 5.2e-178 591.4 0.0 1.0 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Beta_elim_lyase PF01212.16 KFM02869.1 - 9.3e-06 24.9 0.0 1.2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.14 KFM02869.1 - 0.006 15.0 0.1 0.055 11.8 0.0 2.0 1 1 1 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain PI3_PI4_kinase PF00454.22 KFM02870.1 - 1.4e-59 201.3 0.0 1.9e-59 201.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase zf-GRF PF06839.7 KFM02871.1 - 6.1e-13 48.4 2.7 6.1e-13 48.4 1.9 3.0 2 1 0 2 2 2 1 GRF zinc finger zf-CCHC PF00098.18 KFM02871.1 - 0.002 17.9 0.9 0.002 17.9 0.7 3.9 3 0 0 3 3 3 1 Zinc knuckle zf-DHHC PF01529.15 KFM02871.1 - 0.0036 16.7 4.7 0.0036 16.7 3.2 3.5 2 1 1 3 3 3 1 DHHC palmitoyltransferase Apc4 PF12896.2 KFM02872.1 - 2.1e-54 184.0 10.0 2.1e-54 184.0 7.0 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 4 HTH_43 PF09904.4 KFM02872.1 - 0.054 13.2 0.1 0.19 11.5 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn helix Na_Pi_cotrans PF02690.10 KFM02873.1 - 6.1e-56 188.0 29.7 3.9e-30 104.4 5.3 2.8 2 1 1 3 3 3 2 Na+/Pi-cotransporter Sel1 PF08238.7 KFM02874.1 - 1.8e-17 63.3 38.7 0.00017 22.0 0.1 9.6 10 0 0 10 10 10 5 Sel1 repeat TPR_16 PF13432.1 KFM02874.1 - 0.0044 17.6 3.8 0.26 12.0 0.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat SYS1 PF09801.4 KFM02875.1 - 1.3e-37 128.9 3.5 1.4e-37 128.8 2.4 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Oxidored_q2 PF00420.19 KFM02875.1 - 0.45 10.1 4.4 1.9 8.1 3.2 1.8 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Tweety PF04906.8 KFM02875.1 - 4.1 5.7 6.7 0.1 10.9 0.3 1.4 2 0 0 2 2 2 0 Tweety BTD PF09270.5 KFM02876.1 - 2.7e-65 218.9 0.0 4.2e-65 218.3 0.0 1.3 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.6 KFM02876.1 - 3.5e-56 189.5 0.8 6.3e-56 188.7 0.5 1.4 1 0 0 1 1 1 1 LAG1, DNA binding TIG PF01833.19 KFM02876.1 - 1.4e-08 34.5 1.1 1.4e-07 31.3 0.0 2.6 2 0 0 2 2 2 1 IPT/TIG domain Ig_2 PF13895.1 KFM02876.1 - 0.045 13.8 0.1 0.47 10.6 0.0 2.6 3 0 0 3 3 3 0 Immunoglobulin domain 7tm_1 PF00001.16 KFM02877.1 - 1.6e-67 227.3 16.9 2.4e-67 226.7 11.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CholecysA-Rec_N PF09193.5 KFM02877.1 - 7.7e-25 86.5 0.1 1.6e-24 85.4 0.1 1.6 1 0 0 1 1 1 1 Cholecystokinin A receptor, N-terminal 7TM_GPCR_Srsx PF10320.4 KFM02877.1 - 5.3e-08 32.3 23.2 3.7e-07 29.5 16.1 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Brr6_like_C_C PF10104.4 KFM02877.1 - 0.74 9.3 9.3 0.033 13.7 0.9 2.8 2 2 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain RabGAP-TBC PF00566.13 KFM02878.1 - 6.7e-15 55.1 6.2 4.5e-12 45.8 1.8 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain SAM_2 PF07647.12 KFM02879.1 - 4.8e-06 26.3 0.0 1.4e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFM02879.1 - 0.0069 16.5 0.0 0.024 14.8 0.0 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4446 PF14584.1 KFM02879.1 - 0.35 10.6 6.3 0.05 13.4 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) V_ATPase_I PF01496.14 KFM02879.1 - 7.7 4.2 12.0 16 3.1 8.3 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1515 PF07439.6 KFM02879.1 - 9.9 6.0 7.1 0.79 9.5 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1515) RVT_1 PF00078.22 KFM02880.1 - 0.0065 15.8 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) I-set PF07679.11 KFM02881.1 - 5.7e-28 96.6 0.0 3.1e-15 55.8 0.0 3.4 4 0 0 4 4 4 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM02881.1 - 5.6e-22 77.6 0.1 3.8e-10 39.7 0.0 2.8 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 KFM02881.1 - 3.8e-15 56.1 0.2 2.2e-09 37.6 0.0 3.0 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 KFM02881.1 - 6.9e-12 45.3 0.0 0.00011 22.2 0.0 2.9 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.12 KFM02881.1 - 3e-09 36.7 1.0 5.1e-05 23.1 0.0 3.5 2 1 0 2 2 2 2 Immunoglobulin V-set domain Kazal_2 PF07648.10 KFM02881.1 - 3.6e-08 33.1 5.0 3.6e-08 33.1 3.4 2.2 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 KFM02881.1 - 6.2e-06 26.1 11.2 1.6e-05 24.7 7.8 1.8 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain EF-hand_1 PF00036.27 KFM02881.1 - 3.9e-05 22.6 0.5 0.00012 21.1 0.2 2.0 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 KFM02881.1 - 7.3e-05 22.3 0.6 0.0012 18.5 0.1 2.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 KFM02881.1 - 0.00076 19.5 5.6 0.0015 18.6 3.0 2.2 2 1 0 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFM02881.1 - 0.0015 18.5 0.5 0.0039 17.2 0.4 1.7 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.1 KFM02881.1 - 0.0029 17.1 2.0 0.0032 17.0 0.3 1.9 2 0 0 2 2 2 1 EF-hand domain pair Gar1 PF04410.9 KFM02882.1 - 2.8e-40 137.3 0.1 4.1e-40 136.7 0.1 1.3 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region PAT1 PF09770.4 KFM02882.1 - 0.58 8.3 20.2 0.71 8.0 14.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 7tm_1 PF00001.16 KFM02883.1 - 1.5e-58 197.9 20.8 2e-58 197.5 14.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM02883.1 - 7.7e-10 38.3 20.4 1.2e-09 37.7 14.2 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Git3 PF11710.3 KFM02883.1 - 0.039 13.5 10.6 0.11 12.0 7.4 1.8 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 PLAC8 PF04749.12 KFM02883.1 - 2.4 8.7 8.8 6.1 7.4 0.0 3.2 2 1 1 3 3 3 0 PLAC8 family DUF2962 PF11176.3 KFM02884.1 - 3e-44 150.3 8.7 3.5e-44 150.0 6.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) RINGv PF12906.2 KFM02885.1 - 7.3e-16 57.9 16.0 1.9e-15 56.6 11.1 1.8 1 0 0 1 1 1 1 RING-variant domain DctQ PF04290.7 KFM02885.1 - 0.035 13.8 0.3 0.05 13.3 0.2 1.2 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component 7tm_7 PF08395.7 KFM02885.1 - 0.34 9.8 3.0 0.37 9.7 1.4 1.4 1 1 1 2 2 2 0 7tm Chemosensory receptor FANCL_C PF11793.3 KFM02885.1 - 2.7 8.0 11.7 2.8 7.9 6.2 2.5 3 0 0 3 3 3 0 FANCL C-terminal domain TMEM192 PF14802.1 KFM02887.1 - 1.1e-80 269.8 2.2 1.3e-80 269.6 1.5 1.0 1 0 0 1 1 1 1 TMEM192 family Fig1 PF12351.3 KFM02887.1 - 0.047 13.5 1.5 0.05 13.4 0.4 1.5 1 1 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 NfeD PF01957.13 KFM02887.1 - 0.12 12.4 0.2 0.37 10.9 0.0 1.7 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding Kelch_1 PF01344.20 KFM02888.1 - 8.1e-82 268.5 18.4 4.8e-15 54.8 0.5 6.8 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.1 KFM02888.1 - 6e-43 143.3 3.6 9.1e-08 31.9 0.0 6.3 1 1 5 6 6 6 6 Kelch motif Kelch_3 PF13415.1 KFM02888.1 - 1.4e-33 114.3 13.2 2.2e-06 27.6 0.1 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain BTB PF00651.26 KFM02888.1 - 9.3e-32 109.3 0.1 2.1e-31 108.2 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.10 KFM02888.1 - 1.2e-31 107.3 10.2 1.5e-05 24.5 0.1 6.3 6 0 0 6 6 6 5 Kelch motif BACK PF07707.10 KFM02888.1 - 1.5e-30 105.0 1.5 5.3e-30 103.3 1.0 2.0 1 1 0 1 1 1 1 BTB And C-terminal Kelch Kelch_4 PF13418.1 KFM02888.1 - 3.1e-28 97.2 7.2 6.6e-05 22.6 0.1 6.3 4 1 2 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 KFM02888.1 - 1.1e-07 31.5 16.6 0.3 11.0 0.1 5.4 5 0 0 5 5 5 4 Kelch motif PQQ_3 PF13570.1 KFM02888.1 - 0.0031 17.7 10.2 1.5 9.1 0.0 4.9 5 0 0 5 5 5 1 PQQ-like domain Ashwin PF15323.1 KFM02888.1 - 0.1 12.5 0.4 0.17 11.8 0.3 1.2 1 0 0 1 1 1 0 Developmental protein FA_hydroxylase PF04116.8 KFM02889.1 - 2.8e-15 56.7 17.5 2.8e-15 56.7 12.1 1.9 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Peptidase_M14 PF00246.19 KFM02890.1 - 3.6e-63 213.7 0.0 4.5e-63 213.4 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.1 KFM02890.1 - 1.2e-15 57.3 0.0 1.8e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 KFM02890.1 - 2.9e-07 30.4 0.0 5.1e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4480) AstE_AspA PF04952.9 KFM02890.1 - 0.051 12.4 0.1 0.13 11.1 0.0 1.6 1 1 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family DUF2817 PF10994.3 KFM02890.1 - 0.16 11.0 0.1 0.24 10.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) CUB PF00431.15 KFM02891.1 - 1.5e-187 610.8 6.6 2.9e-40 136.7 0.2 5.3 5 0 0 5 5 5 5 CUB domain Astacin PF01400.19 KFM02891.1 - 4e-73 244.8 0.1 9.3e-73 243.6 0.0 1.6 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) FXa_inhibition PF14670.1 KFM02891.1 - 1.1e-19 70.2 28.3 1.1e-09 38.2 6.7 2.9 2 0 0 2 2 2 2 Coagulation Factor Xa inhibitory site EGF_CA PF07645.10 KFM02891.1 - 2.3e-12 46.6 30.7 3.6e-07 30.0 5.9 2.9 2 0 0 2 2 2 2 Calcium-binding EGF domain cEGF PF12662.2 KFM02891.1 - 4.9e-09 35.6 6.7 6.2e-05 22.5 0.9 3.3 2 0 0 2 2 2 2 Complement Clr-like EGF-like EGF_3 PF12947.2 KFM02891.1 - 3.3e-05 23.7 24.3 0.00058 19.7 3.5 3.4 2 1 1 3 3 3 2 EGF domain CUB_2 PF02408.15 KFM02891.1 - 6e-05 22.5 5.6 0.71 9.4 0.1 4.4 4 0 0 4 4 4 3 CUB-like domain Peptidase_M10 PF00413.19 KFM02891.1 - 0.003 17.2 0.1 0.55 9.9 0.1 2.6 2 0 0 2 2 2 1 Matrixin Reprolysin_2 PF13574.1 KFM02891.1 - 0.0057 16.7 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFM02891.1 - 0.018 14.5 0.1 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like SPARC_Ca_bdg PF10591.4 KFM02892.1 - 2.6e-32 111.1 1.8 4.4e-32 110.4 1.3 1.4 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Thyroglobulin_1 PF00086.13 KFM02892.1 - 2.3e-15 55.6 6.9 2.3e-15 55.6 4.8 3.3 4 0 0 4 4 4 1 Thyroglobulin type-1 repeat Kazal_2 PF07648.10 KFM02892.1 - 1.1e-10 41.2 7.0 1.1e-10 41.2 4.8 2.9 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 KFM02892.1 - 1.2e-08 34.8 9.0 1.2e-08 34.8 6.2 3.9 4 1 0 4 4 4 1 Kazal-type serine protease inhibitor domain EF-hand_6 PF13405.1 KFM02892.1 - 0.46 10.4 5.9 2.9 8.0 0.1 3.6 4 0 0 4 4 4 0 EF-hand domain CDC45 PF02724.9 KFM02892.1 - 2.1 6.2 6.8 2.6 5.9 4.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Annexin PF00191.15 KFM02893.1 - 1.5e-82 271.4 8.4 9.8e-21 73.4 0.1 4.0 4 0 0 4 4 4 4 Annexin zf-B_box PF00643.19 KFM02894.1 - 0.018 14.9 0.8 0.018 14.9 0.5 1.9 2 0 0 2 2 2 0 B-box zinc finger zf-A20 PF01754.11 KFM02894.1 - 0.023 14.2 0.2 0.038 13.5 0.1 1.4 1 0 0 1 1 1 0 A20-like zinc finger Pox_Ag35 PF03286.9 KFM02894.1 - 0.026 14.0 1.3 0.033 13.7 0.9 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CAP_N PF01213.14 KFM02894.1 - 0.035 13.4 0.3 0.04 13.2 0.2 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal I-set PF07679.11 KFM02895.1 - 8e-108 352.5 0.0 1.3e-22 79.4 0.0 5.8 5 1 0 5 5 5 5 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM02895.1 - 6.3e-59 196.0 0.1 1.9e-11 43.8 0.0 5.7 5 0 0 5 5 5 5 Immunoglobulin domain Ig_3 PF13927.1 KFM02895.1 - 1.7e-39 134.0 0.1 1.5e-07 31.8 0.0 6.3 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.20 KFM02895.1 - 6.4e-29 99.8 0.0 0.00013 22.0 0.0 6.0 5 0 0 5 5 5 5 Immunoglobulin domain V-set PF07686.12 KFM02895.1 - 6.1e-22 77.6 7.6 0.002 17.9 0.0 8.1 6 3 0 6 6 6 5 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM02895.1 - 1.2e-16 60.3 1.6 0.015 15.1 0.0 6.6 6 0 0 6 6 6 5 CD80-like C2-set immunoglobulin domain C1-set PF07654.10 KFM02895.1 - 1.1e-05 25.3 0.1 0.19 11.7 0.0 4.5 5 0 0 5 5 5 2 Immunoglobulin C1-set domain BiPBP_C PF06832.7 KFM02895.1 - 0.00013 21.8 0.0 3.1 7.7 0.0 4.0 4 0 0 4 4 3 2 Penicillin-Binding Protein C-terminus Family Receptor_2B4 PF11465.3 KFM02895.1 - 0.00039 20.2 0.0 0.4 10.6 0.0 4.2 5 0 0 5 5 5 1 Natural killer cell receptor 2B4 C2-set PF05790.10 KFM02895.1 - 0.039 13.9 0.1 8.9 6.3 0.1 3.8 3 0 0 3 3 3 0 Immunoglobulin C2-set domain DsrC PF04358.8 KFM02895.1 - 0.14 12.4 0.0 0.7 10.1 0.0 2.2 2 0 0 2 2 2 0 DsrC like protein adh_short PF00106.20 KFM02896.1 - 1.8e-33 115.7 2.4 1.8e-33 115.7 1.6 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFM02896.1 - 1.8e-29 103.1 0.1 2.2e-29 102.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFM02896.1 - 6.4e-16 58.5 2.8 1.3e-15 57.5 1.1 1.8 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 KFM02896.1 - 0.00098 18.6 0.1 0.0037 16.7 0.1 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFM02896.1 - 0.0027 17.7 0.2 0.0058 16.6 0.2 1.8 1 1 0 1 1 1 1 NADH(P)-binding Tctex-1 PF03645.8 KFM02896.1 - 0.15 11.9 0.1 0.27 11.0 0.1 1.4 1 0 0 1 1 1 0 Tctex-1 family SH3_9 PF14604.1 KFM02897.1 - 2.5e-58 193.4 2.4 4.1e-16 58.3 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain SH3_1 PF00018.23 KFM02897.1 - 6.9e-50 166.2 1.8 4.5e-12 45.1 0.0 4.3 4 0 0 4 4 4 4 SH3 domain SH3_2 PF07653.12 KFM02897.1 - 7.2e-36 121.4 1.8 2.6e-09 36.4 0.1 4.3 4 0 0 4 4 4 4 Variant SH3 domain zf-C3HC4 PF00097.20 KFM02897.1 - 3.5e-09 36.1 7.0 6.8e-09 35.2 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM02897.1 - 7.7e-09 35.4 8.2 1.6e-08 34.4 5.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM02897.1 - 3.2e-08 33.2 8.0 7.3e-08 32.1 5.5 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 KFM02897.1 - 2.9e-07 30.0 5.7 6.6e-07 28.9 4.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 KFM02897.1 - 3.9e-07 29.7 6.8 7.2e-07 28.8 4.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFM02897.1 - 3.6e-06 26.5 8.7 6.5e-06 25.7 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFM02897.1 - 8e-05 22.4 7.8 0.00015 21.5 5.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KFM02897.1 - 0.00017 21.0 4.8 0.00017 21.0 3.3 1.8 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-MIZ PF02891.15 KFM02897.1 - 0.0024 17.3 5.5 0.0051 16.3 3.8 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 KFM02897.1 - 0.099 12.1 2.6 0.31 10.6 1.8 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Trm112p PF03966.11 KFM02897.1 - 1.4 9.3 5.9 4.5 7.7 4.1 1.9 1 0 0 1 1 1 0 Trm112p-like protein Voltage_CLC PF00654.15 KFM02898.1 - 9.7e-102 340.6 20.1 1.4e-101 340.0 13.9 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.23 KFM02898.1 - 2.2e-15 56.1 0.5 3.6e-09 36.2 0.1 2.4 2 0 0 2 2 2 2 CBS domain DUF2228 PF10228.4 KFM02899.1 - 7e-104 346.8 0.1 1e-103 346.3 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2228) I-set PF07679.11 KFM02900.1 - 7.5e-06 25.7 0.0 2e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.1 KFM02900.1 - 0.00044 20.6 0.1 0.00097 19.5 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFM02900.1 - 0.0065 16.3 0.2 0.017 14.9 0.1 1.8 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 KFM02900.1 - 0.0097 16.0 0.0 0.025 14.6 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain DUF4446 PF14584.1 KFM02900.1 - 0.031 14.0 0.5 0.054 13.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) ig PF00047.20 KFM02900.1 - 0.036 14.1 0.0 0.12 12.5 0.0 1.9 1 0 0 1 1 1 0 Immunoglobulin domain Acyl-CoA_dh_N PF02771.11 KFM02900.1 - 0.1 13.2 0.2 0.27 11.8 0.1 1.8 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain Glycos_transf_2 PF00535.21 KFM02901.1 - 6.6e-08 32.4 0.0 1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 KFM02902.1 - 2.6e-23 82.3 0.5 3.5e-23 81.9 0.3 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glycos_transf_2 PF00535.21 KFM02902.1 - 2.9e-16 59.6 0.0 5.4e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.9 KFM02902.1 - 2.5e-08 33.2 0.2 6.2e-08 31.9 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFM02902.1 - 0.00045 19.4 0.0 0.0051 15.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.1 KFM02902.1 - 0.03 14.6 0.0 1 9.7 0.0 2.4 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Glyco_tranf_2_3 PF13641.1 KFM02902.1 - 0.037 13.8 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KFM02903.1 - 5.4e-22 78.2 0.0 9e-22 77.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 KFM02903.1 - 2.2e-21 76.1 0.9 4.6e-21 75.1 0.7 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.1 KFM02903.1 - 1.2e-07 31.7 0.0 2.6e-07 30.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 KFM02903.1 - 7e-07 28.6 0.0 1.8e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFM02903.1 - 1.4e-06 27.5 0.0 1.3e-05 24.4 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 HMG_box_2 PF09011.5 KFM02904.1 - 8e-44 147.8 14.9 3e-27 94.7 4.7 2.3 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.14 KFM02904.1 - 7.5e-41 138.2 12.9 8.8e-26 89.9 1.1 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_5 PF14887.1 KFM02904.1 - 0.00011 21.8 11.0 0.032 14.0 1.8 2.3 2 0 0 2 2 2 2 HMG (high mobility group) box 5 Nucleoplasmin PF03066.10 KFM02904.1 - 0.32 10.5 9.7 0.54 9.7 6.7 1.5 1 0 0 1 1 1 0 Nucleoplasmin SAP30_Sin3_bdg PF13867.1 KFM02905.1 - 2.7e-24 84.7 0.0 3.8e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 zf-SAP30 PF13866.1 KFM02905.1 - 2.9e-10 39.6 0.1 5.8e-10 38.6 0.1 1.5 1 0 0 1 1 1 1 SAP30 zinc-finger SCRG1 PF15224.1 KFM02906.1 - 3.1e-46 155.0 4.5 3.6e-46 154.8 3.1 1.0 1 0 0 1 1 1 1 Scrapie-responsive protein 1 HLH PF00010.21 KFM02907.1 - 4.6e-18 64.6 0.2 4.6e-18 64.6 0.1 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Trypan_glycop PF00913.14 KFM02907.1 - 0.029 13.2 1.0 0.036 12.9 0.7 1.2 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) BetR PF08667.5 KFM02907.1 - 0.068 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 BetR domain Sec7 PF01369.15 KFM02908.1 - 1.1e-38 132.8 0.1 1.6e-38 132.3 0.1 1.1 1 0 0 1 1 1 1 Sec7 domain F-box-like PF12937.2 KFM02908.1 - 1.1e-07 31.5 0.6 2.7e-07 30.1 0.4 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFM02908.1 - 0.0041 16.7 1.3 0.0076 15.8 0.1 2.1 2 0 0 2 2 2 1 F-box domain PRANC PF09372.5 KFM02908.1 - 0.027 14.4 0.1 0.12 12.4 0.0 2.2 2 0 0 2 2 2 0 PRANC domain CEP44 PF15007.1 KFM02909.1 - 6.2e-54 181.2 0.9 1.6e-53 179.9 0.6 1.7 1 0 0 1 1 1 1 Centrosomal spindle body, CEP44 LELP1 PF15042.1 KFM02909.1 - 0.053 13.7 1.1 0.43 10.7 0.1 2.4 2 0 0 2 2 2 0 Late cornified envelope-like proline-rich protein 1 adh_short PF00106.20 KFM02910.1 - 9.6e-35 119.9 0.4 1.3e-34 119.5 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFM02910.1 - 1.4e-15 57.4 0.1 2e-15 56.8 0.1 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFM02910.1 - 5.8e-15 55.7 0.0 8.5e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KFM02910.1 - 3.6e-08 33.1 0.1 4.4e-08 32.8 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KFM02910.1 - 7.7e-06 25.3 0.4 1.2e-05 24.6 0.3 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFM02910.1 - 1.4e-05 25.2 0.1 2.3e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KFM02910.1 - 2.5e-05 23.1 0.2 3.3e-05 22.7 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KFM02910.1 - 0.0044 15.9 0.1 0.0063 15.4 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 KFM02910.1 - 0.026 13.4 0.2 0.04 12.8 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Methyltransf_31 PF13847.1 KFM02910.1 - 0.057 13.0 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.14 KFM02910.1 - 0.12 11.5 0.1 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 KFM02910.1 - 0.12 12.0 0.3 0.19 11.3 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Wax2_C PF12076.3 KFM02910.1 - 0.12 12.0 0.1 5.8 6.6 0.0 2.6 2 1 1 3 3 3 0 WAX2 C-terminal domain Neur_chan_LBD PF02931.18 KFM02911.1 - 3.2e-50 170.2 0.1 5.5e-50 169.5 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFM02911.1 - 5e-44 150.9 5.9 1e-37 130.2 2.0 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Myelin_PLP PF01275.14 KFM02914.1 - 1.4e-107 358.6 24.0 1.6e-107 358.4 16.6 1.0 1 0 0 1 1 1 1 Myelin proteolipid protein (PLP or lipophilin) DUF2701 PF10857.3 KFM02914.1 - 0.3 10.8 0.0 0.3 10.8 0.0 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF2701) WD40 PF00400.27 KFM02915.1 - 4.7e-60 197.4 29.4 2e-10 40.1 0.2 11.0 11 0 0 11 11 11 8 WD domain, G-beta repeat Nup160 PF11715.3 KFM02915.1 - 0.0012 17.0 6.8 0.22 9.5 0.0 4.3 4 1 1 5 5 5 3 Nucleoporin Nup120/160 Ank PF00023.25 KFM02916.1 - 7.4e-44 145.4 7.8 2.1e-09 36.7 0.1 6.4 6 0 0 6 6 6 6 Ankyrin repeat Ank_2 PF12796.2 KFM02916.1 - 8.6e-41 138.1 5.5 4.1e-19 68.6 0.2 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFM02916.1 - 1.1e-30 105.4 1.8 4.9e-10 39.6 0.0 4.9 3 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM02916.1 - 4.7e-30 100.6 4.6 1.1e-06 28.2 0.1 7.0 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 KFM02916.1 - 5.4e-24 83.6 6.2 6.4e-07 29.4 0.0 6.3 1 1 5 6 6 6 6 Ankyrin repeats (many copies) SOCS_box PF07525.11 KFM02916.1 - 1.1e-12 47.5 7.1 2.3e-12 46.5 4.9 1.6 1 0 0 1 1 1 1 SOCS box SPC22 PF04573.7 KFM02917.1 - 5.5e-54 182.0 0.2 9.8e-54 181.2 0.1 1.4 1 1 0 1 1 1 1 Signal peptidase subunit AsmA_2 PF13502.1 KFM02917.1 - 0.041 13.2 0.5 0.065 12.5 0.3 1.4 1 1 0 1 1 1 0 AsmA-like C-terminal region PDGF PF00341.12 KFM02918.1 - 5e-23 81.0 7.2 5e-23 81.0 5.0 3.2 3 1 0 3 3 3 1 PDGF/VEGF domain CXCXC PF03128.9 KFM02918.1 - 5.4e-11 41.7 47.4 0.007 16.4 2.6 8.9 8 0 0 8 8 8 5 CXCXC repeat zf-GRF PF06839.7 KFM02919.1 - 3e-34 116.6 12.6 6.7e-19 67.5 3.2 4.4 3 1 1 4 4 4 2 GRF zinc finger H2TH PF06831.9 KFM02919.1 - 1.1e-12 47.5 0.0 2.2e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.19 KFM02919.1 - 3.1e-07 30.7 0.0 1.5e-06 28.5 0.0 2.1 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase N-terminal domain zf-RanBP PF00641.13 KFM02919.1 - 0.00012 21.0 1.4 0.00012 21.0 1.0 3.3 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others FBP PF07299.6 KFM02919.1 - 0.016 14.5 4.1 0.63 9.3 1.0 2.4 2 0 0 2 2 2 0 Fibronectin-binding protein (FBP) Asparaginase_2 PF01112.13 KFM02920.1 - 4.9e-103 344.1 0.5 5.8e-103 343.9 0.3 1.0 1 0 0 1 1 1 1 Asparaginase PX PF00787.19 KFM02922.1 - 2.7e-19 69.0 1.0 3.7e-19 68.5 0.0 1.7 2 0 0 2 2 2 1 PX domain DUF641 PF04859.7 KFM02922.1 - 0.016 14.9 0.2 0.039 13.7 0.1 1.6 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) IncA PF04156.9 KFM02922.1 - 0.4 10.2 4.6 0.68 9.4 3.2 1.3 1 0 0 1 1 1 0 IncA protein Snf7 PF03357.16 KFM02923.1 - 3.9e-43 146.7 11.9 5.7e-43 146.2 8.2 1.2 1 0 0 1 1 1 1 Snf7 Glyco_hydro_65m PF03632.10 KFM02923.1 - 0.065 11.8 0.8 0.079 11.6 0.5 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65 central catalytic domain Trns_repr_metal PF02583.12 KFM02923.1 - 0.11 12.7 2.0 0.23 11.7 1.4 1.5 1 0 0 1 1 1 0 Metal-sensitive transcriptional repressor SYF2 PF08231.7 KFM02923.1 - 0.19 11.8 3.1 0.33 11.0 2.2 1.5 1 0 0 1 1 1 0 SYF2 splicing factor TBPIP PF07106.8 KFM02923.1 - 0.83 9.1 10.4 1.2 8.6 2.9 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Enkurin PF13864.1 KFM02923.1 - 4.8 7.4 10.6 1.4 9.1 0.1 3.4 2 1 2 4 4 4 0 Calmodulin-binding Cwf_Cwc_15 PF04889.7 KFM02923.1 - 7.9 6.1 12.4 0.34 10.5 5.0 1.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein zf-AN1 PF01428.11 KFM02924.1 - 7e-20 70.6 22.1 3.9e-11 42.6 7.2 2.7 3 0 0 3 3 3 2 AN1-like Zinc finger Inositol_P PF00459.20 KFM02925.1 - 7.8e-82 274.6 0.0 9.6e-82 274.3 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF366 PF04017.7 KFM02925.1 - 0.077 12.2 0.0 2.7 7.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF366) Lipocalin PF00061.18 KFM02926.1 - 1.1e-25 90.2 3.8 1.3e-25 90.1 2.6 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.1 KFM02926.1 - 0.0015 18.2 2.2 0.0019 17.8 1.6 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin PF00061.18 KFM02927.1 - 7.9e-26 90.7 1.0 8.7e-26 90.6 0.7 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.1 KFM02927.1 - 7.5e-06 25.6 1.6 1.3e-05 24.9 1.1 1.4 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Toxin_56 PF15534.1 KFM02927.1 - 0.064 13.7 0.9 0.78 10.2 0.2 2.1 2 0 0 2 2 2 0 Putative toxin 56 Lipocalin PF00061.18 KFM02928.1 - 1.4e-15 57.5 1.0 1.5e-15 57.4 0.7 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family MRP_L53 PF10780.4 KFM02929.1 - 8.4e-15 54.4 0.0 1.6e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 zf-C2H2 PF00096.21 KFM02930.1 - 0.02 15.1 0.1 0.079 13.3 0.0 2.1 1 0 0 1 1 1 0 Zinc finger, C2H2 type TPD52 PF04201.10 KFM02931.1 - 1.7e-69 232.6 8.0 1.9e-69 232.4 5.5 1.0 1 0 0 1 1 1 1 Tumour protein D52 family PEP-utilisers_N PF05524.8 KFM02931.1 - 0.0047 16.7 2.6 0.0087 15.8 1.8 1.4 1 0 0 1 1 1 1 PEP-utilising enzyme, N-terminal Wx5_PLAF3D7 PF09688.5 KFM02931.1 - 0.0066 16.4 3.3 0.012 15.5 2.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (Wx5_PLAF3D7) ERM PF00769.14 KFM02931.1 - 0.0072 15.8 4.8 0.0094 15.5 3.3 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF2265 PF10023.4 KFM02931.1 - 0.0093 15.1 0.5 0.012 14.7 0.4 1.1 1 0 0 1 1 1 1 Predicted aminopeptidase (DUF2265) Occludin_ELL PF07303.8 KFM02931.1 - 0.014 16.1 3.4 0.17 12.6 0.1 2.2 1 1 1 2 2 2 0 Occludin homology domain Apolipoprotein PF01442.13 KFM02931.1 - 0.015 14.7 6.6 0.032 13.7 4.6 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain TBPIP PF07106.8 KFM02931.1 - 0.031 13.8 9.2 0.31 10.5 5.6 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) AAA_13 PF13166.1 KFM02931.1 - 0.065 11.6 9.2 0.33 9.3 6.4 1.7 1 1 0 1 1 1 0 AAA domain GvpK PF05121.7 KFM02931.1 - 0.066 13.0 2.9 0.41 10.4 1.9 2.2 2 1 0 2 2 2 0 Gas vesicle protein K RNA_pol_A_CTD PF03118.10 KFM02931.1 - 0.083 12.3 0.9 0.22 10.9 0.6 1.7 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain IncA PF04156.9 KFM02931.1 - 0.12 12.0 10.4 0.21 11.1 7.2 1.6 1 1 0 1 1 1 0 IncA protein APG6 PF04111.7 KFM02931.1 - 0.15 11.0 5.0 0.19 10.7 3.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 HsbA PF12296.3 KFM02931.1 - 0.22 11.3 5.0 0.14 11.9 0.5 2.4 1 1 1 2 2 2 0 Hydrophobic surface binding protein A RsbRD_N PF14361.1 KFM02931.1 - 0.22 11.9 3.7 1.7 9.1 0.4 2.7 2 1 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain Cob_adeno_trans PF01923.13 KFM02931.1 - 0.24 11.1 2.8 0.34 10.6 1.8 1.4 1 1 0 1 1 1 0 Cobalamin adenosyltransferase WXG100 PF06013.7 KFM02931.1 - 0.25 11.3 5.1 4.2 7.4 0.1 3.0 3 1 0 3 3 3 0 Proteins of 100 residues with WXG DUF4164 PF13747.1 KFM02931.1 - 0.27 11.4 5.1 11 6.2 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) Siah-Interact_N PF09032.6 KFM02931.1 - 0.36 10.9 6.7 0.13 12.3 1.9 2.1 1 1 1 2 2 2 0 Siah interacting protein, N terminal SlyX PF04102.7 KFM02931.1 - 0.37 11.1 6.2 0.91 9.9 1.6 2.7 2 1 1 3 3 3 0 SlyX Ada3 PF10198.4 KFM02931.1 - 0.53 10.0 5.2 0.82 9.4 3.6 1.4 1 1 0 1 1 1 0 Histone acetyltransferases subunit 3 Macoilin PF09726.4 KFM02931.1 - 0.82 7.8 9.9 0.34 9.1 5.2 1.4 1 1 0 1 1 1 0 Transmembrane protein DUF883 PF05957.8 KFM02931.1 - 0.85 10.0 6.1 1.3 9.4 0.7 3.0 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) VASP_tetra PF08776.6 KFM02931.1 - 0.92 8.8 7.0 0.26 10.6 2.7 1.7 2 0 0 2 2 1 0 VASP tetramerisation domain Spc7 PF08317.6 KFM02931.1 - 1.1 7.8 9.2 1.1 7.8 5.7 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF724 PF05266.9 KFM02931.1 - 1.2 8.6 7.6 1.3 8.6 4.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF724) OmpH PF03938.9 KFM02931.1 - 2 8.3 9.9 3.9 7.3 6.9 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Med9 PF07544.8 KFM02931.1 - 3.2 7.5 8.1 1.6 8.5 2.1 2.8 2 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Uds1 PF15456.1 KFM02931.1 - 3.2 7.7 10.1 12 5.9 7.0 1.9 1 1 0 1 1 1 0 Up-regulated During Septation Prefoldin_2 PF01920.15 KFM02931.1 - 4.8 6.9 13.0 12 5.6 5.3 2.6 1 1 1 2 2 2 0 Prefoldin subunit MRP-S35 PF10246.4 KFM02932.1 - 3.4e-51 171.5 0.0 3.9e-51 171.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein MRP-S35 S1 PF00575.18 KFM02932.1 - 0.013 15.5 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 S1 RNA binding domain HLH PF00010.21 KFM02933.1 - 2.5e-17 62.2 2.6 4.5e-17 61.4 1.8 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.8 KFM02933.1 - 7.5e-13 47.9 0.0 1.3e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Hairy Orange Stathmin PF00836.14 KFM02934.1 - 1.8e-73 244.7 24.1 2.2e-73 244.5 16.7 1.1 1 0 0 1 1 1 1 Stathmin family HTH_8 PF02954.14 KFM02934.1 - 0.049 13.1 0.7 0.049 13.1 0.5 1.9 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family CDC37_N PF03234.9 KFM02934.1 - 0.086 13.1 13.1 0.14 12.4 9.0 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding OS-D PF03392.8 KFM02934.1 - 0.32 10.9 4.6 0.53 10.2 1.9 2.3 1 1 1 2 2 2 0 Insect pheromone-binding family, A10/OS-D Fib_alpha PF08702.5 KFM02934.1 - 1.1 9.3 9.7 1.6 8.8 6.7 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family RNA_pol_Rpb1_4 PF05000.12 KFM02934.1 - 1.5 8.6 4.2 0.44 10.3 0.6 1.8 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 4 IL7 PF01415.11 KFM02935.1 - 0.00031 20.3 5.3 0.0004 20.0 3.7 1.1 1 0 0 1 1 1 1 Interleukin 7/9 family Tweety PF04906.8 KFM02935.1 - 0.019 13.4 0.1 0.022 13.1 0.0 1.0 1 0 0 1 1 1 0 Tweety zf-C2HC_2 PF13913.1 KFM02936.1 - 7.1e-15 54.2 7.1 6.6e-09 35.2 0.5 2.6 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-ribbon_3 PF13248.1 KFM02936.1 - 0.0073 15.4 4.0 0.0073 15.4 2.8 3.0 3 0 0 3 3 3 1 zinc-ribbon domain DZR PF12773.2 KFM02936.1 - 0.016 15.0 11.6 0.058 13.2 1.7 3.3 3 0 0 3 3 3 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 KFM02936.1 - 0.02 14.3 5.8 0.02 14.3 4.0 3.1 3 0 0 3 3 3 0 zinc-ribbon domain Nairovirus_M PF07948.6 KFM02936.1 - 0.031 12.4 0.2 0.051 11.7 0.1 1.2 1 0 0 1 1 1 0 Nairovirus M polyprotein-like DUF2321 PF10083.4 KFM02936.1 - 0.094 12.2 0.4 0.31 10.5 0.3 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) HypA PF01155.14 KFM02936.1 - 0.14 11.8 9.1 2.8 7.6 1.4 3.1 3 0 0 3 3 3 0 Hydrogenase expression/synthesis hypA family zf-C2H2 PF00096.21 KFM02936.1 - 1.2 9.5 0.1 1.2 9.5 0.0 4.2 5 0 0 5 5 3 0 Zinc finger, C2H2 type Rod_cone_degen PF15201.1 KFM02936.1 - 4.4 7.2 7.1 0.32 10.8 1.1 2.0 2 0 0 2 2 2 0 Progressive rod-cone degeneration zinc-ribbons_6 PF07191.7 KFM02936.1 - 8.7 6.2 10.9 0.63 9.8 0.4 2.8 3 0 0 3 3 3 0 zinc-ribbons zf-C2H2_6 PF13912.1 KFM02936.1 - 9.5 6.2 8.7 15 5.6 0.0 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger PKI PF02827.11 KFM02937.1 - 5.9e-35 119.2 0.9 6.5e-35 119.0 0.6 1.0 1 0 0 1 1 1 1 cAMP-dependent protein kinase inhibitor Xlink PF00193.12 KFM02942.1 - 1.8e-08 34.3 0.1 3.7e-08 33.3 0.1 1.6 1 0 0 1 1 1 1 Extracellular link domain Sushi PF00084.15 KFM02942.1 - 5.4e-06 26.6 0.6 5.4e-06 26.6 0.4 2.1 2 0 0 2 2 2 1 Sushi domain (SCR repeat) SIT PF15330.1 KFM02942.1 - 0.0041 17.2 0.7 0.0097 16.0 0.1 2.0 2 0 0 2 2 2 1 SHP2-interacting transmembrane adaptor protein, SIT Ly49 PF08391.5 KFM02942.1 - 0.041 14.0 0.3 0.092 12.8 0.2 1.6 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region MLANA PF14991.1 KFM02942.1 - 0.072 13.1 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein melan-A MHC2-interact PF09307.5 KFM02942.1 - 0.081 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 CLIP, MHC2 interacting P12 PF12669.2 KFM02942.1 - 0.11 12.7 0.1 0.11 12.7 0.1 1.9 2 0 0 2 2 2 0 Virus attachment protein p12 family LRR_6 PF13516.1 KFM02943.1 - 7.2e-19 65.6 35.0 0.0012 18.7 0.0 10.9 11 0 0 11 11 11 6 Leucine Rich repeat LRR_4 PF12799.2 KFM02943.1 - 7.8e-13 47.7 21.5 0.0076 15.8 0.4 6.7 4 1 0 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM02943.1 - 1.2e-10 39.9 30.8 1.2 9.4 0.0 11.4 11 1 0 11 11 11 5 Leucine Rich Repeat LRR_8 PF13855.1 KFM02943.1 - 2.9e-10 39.7 29.8 0.0016 18.1 1.4 6.2 2 1 5 7 7 7 6 Leucine rich repeat F-box-like PF12937.2 KFM02943.1 - 1e-08 34.7 0.6 5.2e-08 32.4 0.4 2.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFM02943.1 - 2.6e-05 23.7 1.4 9.4e-05 21.9 0.2 2.6 2 0 0 2 2 2 1 F-box domain LRR_7 PF13504.1 KFM02943.1 - 0.012 15.6 34.3 5.3 7.6 0.1 10.7 9 2 1 10 10 10 0 Leucine rich repeat Mating_N PF12731.2 KFM02943.1 - 0.045 13.6 0.1 1.3 8.9 0.0 2.6 1 1 0 2 2 2 0 Mating-type protein beta 1 CP2 PF04516.10 KFM02944.1 - 7.9e-72 241.1 0.1 1.2e-71 240.5 0.1 1.1 1 0 0 1 1 1 1 CP2 transcription factor SAM_2 PF07647.12 KFM02944.1 - 0.0066 16.2 0.0 0.018 14.8 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 KFM02944.1 - 0.0079 15.9 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_1 PF00536.25 KFM02944.1 - 0.012 15.7 0.0 0.03 14.4 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) CLASP_N PF12348.3 KFM02945.1 - 1.4e-54 184.9 7.6 1.7e-38 132.2 0.0 4.2 4 0 0 4 4 4 3 CLASP N terminal HEAT PF02985.17 KFM02945.1 - 3.7e-16 57.6 11.0 0.004 17.1 0.0 10.7 10 0 0 10 10 10 3 HEAT repeat HEAT_2 PF13646.1 KFM02945.1 - 1.8e-11 44.1 6.3 0.03 14.5 0.2 8.0 5 3 2 9 9 9 4 HEAT repeats HEAT_EZ PF13513.1 KFM02945.1 - 7.7e-09 35.7 0.9 0.38 11.3 0.0 6.5 6 0 0 6 6 6 2 HEAT-like repeat DUF2435 PF10363.4 KFM02945.1 - 2.8e-06 27.1 2.1 0.087 12.7 0.0 3.8 2 1 1 3 3 3 3 Protein of unknown function (DUF2435) Adaptin_N PF01602.15 KFM02945.1 - 3.3e-06 25.7 5.7 0.29 9.4 0.1 6.1 5 1 0 6 6 6 2 Adaptin N terminal region Ipi1_N PF12333.3 KFM02945.1 - 3.7e-06 26.8 1.6 0.0095 15.8 0.1 3.5 3 0 0 3 3 3 2 Rix1 complex component involved in 60S ribosome maturation Vac14_Fab1_bd PF12755.2 KFM02945.1 - 1.4e-05 25.3 3.2 19 5.7 0.0 6.2 6 1 1 7 7 6 0 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 KFM02945.1 - 3.7e-05 23.6 9.0 0.0013 18.5 0.3 5.2 5 1 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Sec7_N PF12783.2 KFM02945.1 - 0.00018 21.0 4.6 2.8 7.3 0.0 4.9 5 0 0 5 5 5 2 Guanine nucleotide exchange factor in Golgi transport N-terminal ParcG PF10274.4 KFM02945.1 - 0.00029 20.8 4.0 0.0022 17.9 0.1 3.5 3 1 1 4 4 4 1 Parkin co-regulated protein TAN PF11640.3 KFM02945.1 - 0.012 15.3 3.2 0.056 13.1 0.1 3.3 2 1 1 3 3 3 0 Telomere-length maintenance and DNA damage repair MMS19_C PF12460.3 KFM02945.1 - 0.041 12.6 5.8 0.062 12.0 0.2 3.6 4 0 0 4 4 4 0 RNAPII transcription regulator C-terminal MMS19_N PF14500.1 KFM02945.1 - 0.047 12.9 1.8 5.7 6.1 0.0 3.6 3 1 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II BRO1 PF03097.13 KFM02946.1 - 4e-109 364.8 3.1 4e-109 364.8 2.1 2.5 2 1 1 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 KFM02946.1 - 3.3e-87 292.2 17.9 3.3e-87 292.2 12.4 1.7 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV DUF501 PF04417.7 KFM02946.1 - 0.16 11.8 0.9 1.3 8.8 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF501) NUC130_3NT PF08158.7 KFM02946.1 - 0.45 10.8 3.4 3.3 8.0 0.2 3.7 4 0 0 4 4 4 0 NUC130/3NT domain DUF592 PF04574.8 KFM02946.1 - 0.84 9.1 7.6 4.5 6.8 0.1 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF592) ALMT PF11744.3 KFM02946.1 - 4.2 5.9 8.4 1.9 7.0 4.0 1.7 2 0 0 2 2 2 0 Aluminium activated malate transporter Ly49 PF08391.5 KFM02946.1 - 6.3 6.9 12.1 0.34 11.0 3.5 2.5 3 0 0 3 3 3 0 Ly49-like protein, N-terminal region R3H PF01424.17 KFM02947.1 - 2.4e-13 49.5 0.2 8.1e-13 47.8 0.0 2.0 2 0 0 2 2 2 1 R3H domain SH3_9 PF14604.1 KFM02948.1 - 7.6e-20 70.2 0.1 1.1e-15 56.9 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KFM02948.1 - 6.2e-17 60.7 0.6 5.7e-15 54.4 0.1 2.3 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 KFM02948.1 - 1.1e-16 59.9 0.2 2.4e-07 30.1 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain C1_1 PF00130.17 KFM02948.1 - 2.7e-09 36.6 11.0 2.7e-09 36.6 7.6 1.8 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4206 PF13901.1 KFM02948.1 - 0.0013 18.3 1.6 0.0021 17.6 1.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4206) zf-DHHC PF01529.15 KFM02948.1 - 0.0019 17.5 3.4 0.004 16.5 2.4 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase RNA_POL_M_15KD PF02150.11 KFM02948.1 - 0.11 12.1 1.3 0.24 11.1 0.9 1.5 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit PHD PF00628.24 KFM02948.1 - 0.15 11.7 8.1 0.33 10.6 5.6 1.6 1 0 0 1 1 1 0 PHD-finger C1_3 PF07649.7 KFM02948.1 - 1.3 9.1 5.0 6.5 6.8 3.5 2.3 1 1 0 1 1 1 0 C1-like domain zf-RING-like PF08746.6 KFM02948.1 - 5.5 7.0 9.9 14 5.7 6.9 1.7 1 0 0 1 1 1 0 RING-like domain Pkinase PF00069.20 KFM02949.1 - 5.7e-80 268.1 0.0 6.7e-80 267.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM02949.1 - 2.4e-37 128.4 0.0 3e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM02949.1 - 0.00085 18.3 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 KFM02949.1 - 0.0052 16.1 0.1 0.0052 16.1 0.0 2.1 3 0 0 3 3 3 1 PhoP regulatory network protein YrbL APH PF01636.18 KFM02949.1 - 0.073 12.8 0.0 0.59 9.8 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ank_2 PF12796.2 KFM02950.1 - 1.1e-07 32.1 0.0 1.8e-06 28.1 0.0 2.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFM02950.1 - 2.4e-07 31.0 0.7 0.005 17.3 0.1 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) UvrD-helicase PF00580.16 KFM02950.1 - 8.2e-07 28.6 1.8 8.2e-07 28.6 1.2 4.4 3 2 0 3 3 3 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 KFM02950.1 - 9e-07 28.9 0.0 0.033 14.3 0.0 2.8 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain Ank PF00023.25 KFM02950.1 - 0.00039 20.0 0.0 1.9 8.4 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 KFM02950.1 - 0.016 15.3 0.1 11 6.6 0.0 4.1 4 0 0 4 4 4 0 Ankyrin repeat Clathrin PF00637.15 KFM02950.1 - 0.03 13.9 20.9 0.092 12.3 2.1 4.8 5 1 1 6 6 6 0 Region in Clathrin and VPS Ank_5 PF13857.1 KFM02950.1 - 0.039 14.2 0.1 11 6.4 0.0 3.0 2 1 0 2 2 2 0 Ankyrin repeats (many copies) AAA_22 PF13401.1 KFM02950.1 - 0.097 12.8 0.6 2.5 8.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain TPR_11 PF13414.1 KFM02951.1 - 1.1e-06 28.2 0.3 3.5e-06 26.5 0.2 1.8 1 1 0 1 1 1 1 TPR repeat Apc3 PF12895.2 KFM02951.1 - 0.0013 18.8 0.3 0.011 15.7 0.1 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 KFM02951.1 - 0.0015 18.3 0.4 1.6 8.7 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFM02951.1 - 0.0044 16.5 0.2 0.56 9.9 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFM02951.1 - 0.005 16.9 0.1 1.6 9.1 0.0 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFM02951.1 - 0.012 15.4 0.2 0.036 14.0 0.2 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat DUF3856 PF12968.2 KFM02951.1 - 0.023 14.5 0.1 5.7 6.7 0.0 2.5 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) DNA_mis_repair PF01119.14 KFM02952.1 - 2.3e-33 114.1 0.3 4.2e-33 113.3 0.2 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KFM02952.1 - 6.3e-09 35.6 0.6 1.2e-08 34.6 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KFM02952.1 - 1.6e-07 30.9 0.0 3.7e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MENTAL PF10457.4 KFM02953.1 - 8.2e-74 246.8 5.3 9.5e-74 246.6 3.7 1.0 1 0 0 1 1 1 1 Cholesterol-capturing domain SNase PF00565.12 KFM02954.1 - 1.5e-57 192.4 0.0 1e-16 61.1 0.0 5.4 4 1 1 5 5 5 5 Staphylococcal nuclease homologue Tecti-min-caps PF09300.5 KFM02954.1 - 0.1 12.3 0.0 0.45 10.3 0.0 2.0 2 0 0 2 2 2 0 Tectiviridae, minor capsid LRR_8 PF13855.1 KFM02955.1 - 7.7e-45 150.4 15.2 3.4e-12 45.9 0.5 5.3 1 1 4 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 KFM02955.1 - 4.2e-28 96.4 12.9 4.6e-07 29.3 0.0 5.7 3 1 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFM02955.1 - 1.5e-19 69.9 0.0 2.2e-12 46.7 0.0 2.4 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_1 PF00560.28 KFM02955.1 - 4.6e-17 59.4 17.5 0.038 14.0 0.2 9.8 10 0 0 10 10 10 4 Leucine Rich Repeat I-set PF07679.11 KFM02955.1 - 3.2e-08 33.3 0.0 5.6e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_7 PF13504.1 KFM02955.1 - 3.9e-07 29.2 18.3 1.3 9.4 0.0 9.3 10 0 0 10 10 9 2 Leucine rich repeat LRR_9 PF14580.1 KFM02955.1 - 7.8e-06 25.5 0.5 0.03 13.8 0.1 2.5 1 1 2 3 3 3 2 Leucine-rich repeat V-set PF07686.12 KFM02955.1 - 2.9e-05 23.9 0.0 8.1e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 KFM02955.1 - 4e-05 23.6 0.0 9.1e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFM02955.1 - 0.0021 18.4 1.9 0.0028 18.1 0.1 2.2 2 0 0 2 2 1 1 Immunoglobulin domain LRRNT PF01462.13 KFM02955.1 - 0.0023 17.3 4.3 0.0023 17.3 3.0 2.0 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain Herpes_gE PF02480.11 KFM02955.1 - 0.0086 14.3 3.4 0.22 9.7 0.1 2.1 1 1 1 2 2 2 2 Alphaherpesvirus glycoprotein E DAG1 PF05454.6 KFM02955.1 - 0.014 14.5 0.6 0.022 13.9 0.4 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) LRR_6 PF13516.1 KFM02955.1 - 0.057 13.5 25.5 1.1 9.5 0.2 8.4 9 1 1 10 10 9 0 Leucine Rich repeat Rifin_STEVOR PF02009.11 KFM02955.1 - 0.17 11.5 0.2 0.26 10.9 0.2 1.2 1 0 0 1 1 1 0 Rifin/stevor family TMEM154 PF15102.1 KFM02955.1 - 0.29 10.8 2.8 2.9 7.6 3.3 1.8 2 0 0 2 2 2 0 TMEM154 protein family gpUL132 PF11359.3 KFM02955.1 - 9.3 5.5 15.1 0.02 14.2 2.7 1.9 2 0 0 2 2 2 0 Glycoprotein UL132 PAX PF00292.13 KFM02956.1 - 1e-55 186.7 0.3 1.4e-55 186.3 0.2 1.2 1 0 0 1 1 1 1 'Paired box' domain Homeobox PF00046.24 KFM02956.1 - 9.6e-21 73.1 2.2 3.1e-20 71.5 1.5 1.9 1 0 0 1 1 1 1 Homeobox domain HTH_32 PF13565.1 KFM02956.1 - 0.00021 22.0 0.8 0.0062 17.3 0.0 2.7 3 0 0 3 3 3 1 Homeodomain-like domain HTH_23 PF13384.1 KFM02956.1 - 0.00027 20.5 0.7 0.015 14.9 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain Homeobox_KN PF05920.6 KFM02956.1 - 0.0013 18.3 0.8 0.004 16.8 0.2 2.0 2 0 0 2 2 2 1 Homeobox KN domain HTH_Tnp_IS1 PF12759.2 KFM02956.1 - 0.12 11.8 0.1 8 5.9 0.0 2.3 2 0 0 2 2 2 0 InsA C-terminal domain Arf PF00025.16 KFM02957.1 - 4.1e-56 188.9 0.0 4.5e-56 188.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KFM02957.1 - 9.2e-09 34.4 0.0 1.5e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit Ras PF00071.17 KFM02957.1 - 1.2e-08 34.5 0.0 1.3e-08 34.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KFM02957.1 - 2.9e-08 33.1 0.0 3.3e-08 32.9 0.0 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KFM02957.1 - 1.6e-06 27.5 0.0 1.9e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KFM02957.1 - 5.3e-05 23.7 0.0 8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KFM02957.1 - 0.04 13.3 0.0 0.041 13.3 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF3887 PF13026.1 KFM02957.1 - 0.12 12.6 0.1 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3887) GRIP PF01465.15 KFM02958.1 - 1.9e-17 62.4 0.7 1.3e-16 59.8 0.0 2.6 2 0 0 2 2 2 1 GRIP domain CENP-Q PF13094.1 KFM02958.1 - 0.0014 18.7 19.7 0.0014 18.7 13.7 6.5 3 1 2 5 5 5 2 CENP-Q, a CENPA-CAD centromere complex subunit Filament PF00038.16 KFM02958.1 - 3.7 6.9 94.2 0.12 11.8 2.3 4.6 2 1 2 4 4 4 0 Intermediate filament protein SPA PF08616.5 KFM02959.1 - 4.4e-14 52.1 0.1 2.1e-13 49.9 0.0 2.1 2 0 0 2 2 2 1 Stabilization of polarity axis DENN PF02141.16 KFM02959.1 - 5.3e-08 32.7 4.3 5.3e-08 32.7 3.0 2.3 2 1 0 2 2 2 1 DENN (AEX-3) domain Avl9 PF09794.4 KFM02959.1 - 0.0017 16.9 0.0 0.0029 16.1 0.0 1.3 1 0 0 1 1 1 1 Transport protein Avl9 RAM PF15320.1 KFM02959.1 - 0.39 10.9 2.6 0.66 10.2 0.2 2.3 2 0 0 2 2 2 0 mRNA cap methylation, RNMT-activating mini protein Myotub-related PF06602.9 KFM02960.1 - 3.5e-109 364.8 0.0 5.5e-109 364.1 0.0 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain SBF2 PF12335.3 KFM02960.1 - 6.1e-108 359.3 2.4 1.1e-107 358.5 1.6 1.4 1 0 0 1 1 1 1 Myotubularin protein DENN PF02141.16 KFM02960.1 - 1.4e-57 194.4 0.2 2.9e-57 193.4 0.2 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 KFM02960.1 - 2.4e-21 75.4 1.4 1.1e-20 73.3 1.0 2.3 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.14 KFM02960.1 - 1.1e-17 63.8 0.0 3.2e-17 62.3 0.0 1.9 1 0 0 1 1 1 1 dDENN domain PH PF00169.24 KFM02960.1 - 1.1e-11 44.8 0.0 2.9e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 PH domain GRAM PF02893.15 KFM02960.1 - 5.4e-11 41.8 0.0 6.6e-10 38.3 0.0 2.7 3 0 0 3 3 3 1 GRAM domain PH_11 PF15413.1 KFM02960.1 - 5.1e-05 23.4 0.0 0.00014 22.0 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain SPA PF08616.5 KFM02960.1 - 7.9e-05 22.3 0.0 0.00024 20.8 0.0 1.8 1 0 0 1 1 1 1 Stabilization of polarity axis PH_9 PF15410.1 KFM02960.1 - 0.082 13.0 0.6 2.2 8.4 0.0 2.6 2 0 0 2 2 2 0 Pleckstrin homology domain MARVEL PF01284.18 KFM02961.1 - 2.5e-17 63.0 2.4 2.8e-17 62.8 1.7 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF4418 PF14387.1 KFM02961.1 - 0.09 12.5 0.7 0.13 12.0 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4418) EGF PF00008.22 KFM02964.1 - 1.8e-23 82.0 53.3 1.1e-07 31.6 1.9 5.4 5 0 0 5 5 5 5 EGF-like domain EGF_2 PF07974.8 KFM02964.1 - 4.8e-08 33.0 61.9 0.00035 20.6 2.8 5.3 5 1 0 5 5 5 3 EGF-like domain hEGF PF12661.2 KFM02964.1 - 1.1e-05 25.1 40.0 0.00044 20.1 2.4 6.1 6 1 0 6 6 6 4 Human growth factor-like EGF EGF_CA PF07645.10 KFM02964.1 - 0.00062 19.6 51.3 0.044 13.7 0.0 5.6 3 2 2 5 5 5 4 Calcium-binding EGF domain Laminin_EGF PF00053.19 KFM02964.1 - 0.0028 17.5 45.6 0.27 11.2 1.3 4.6 1 1 3 4 4 4 3 Laminin EGF-like (Domains III and V) cEGF PF12662.2 KFM02964.1 - 0.018 14.6 10.9 0.049 13.2 1.0 4.7 6 1 0 6 6 6 0 Complement Clr-like EGF-like EGF_3 PF12947.2 KFM02964.1 - 0.052 13.5 45.2 0.26 11.3 2.4 5.1 5 2 0 5 5 5 0 EGF domain FXa_inhibition PF14670.1 KFM02964.1 - 0.67 10.1 47.4 0.38 10.9 4.8 5.4 4 2 1 5 5 5 0 Coagulation Factor Xa inhibitory site PAP_assoc PF03828.14 KFM02965.1 - 7.3e-17 61.0 0.0 2e-16 59.6 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KFM02965.1 - 7e-05 23.0 0.0 0.00013 22.2 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain INCA1 PF15142.1 KFM02966.1 - 0.12 12.1 0.0 0.15 11.8 0.0 1.0 1 0 0 1 1 1 0 INCA1 fn3 PF00041.16 KFM02967.1 - 1.5e-11 44.2 0.0 6e-08 32.7 0.0 2.6 2 0 0 2 2 2 2 Fibronectin type III domain SPRY PF00622.23 KFM02967.1 - 2.9e-07 30.6 0.0 5.8e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 SPRY domain PRY PF13765.1 KFM02967.1 - 0.085 12.3 0.0 1.7 8.2 0.0 2.9 2 1 0 2 2 2 0 SPRY-associated domain Tom37_C PF11801.3 KFM02968.1 - 4.8e-15 55.8 0.0 2.9e-09 37.0 0.0 2.4 1 1 1 2 2 2 2 Tom37 C-terminal domain GST_C_3 PF14497.1 KFM02968.1 - 1.1e-09 38.6 0.0 4e-09 36.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFM02968.1 - 3.8e-08 33.1 0.0 8.1e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.4 KFM02968.1 - 0.0023 18.1 0.0 0.0051 17.0 0.0 1.6 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C PF00043.20 KFM02968.1 - 0.0029 17.5 0.0 0.0061 16.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TSP_C PF05735.7 KFM02969.1 - 3.8e-107 356.3 2.2 7.2e-107 355.4 1.5 1.4 1 0 0 1 1 1 1 Thrombospondin C-terminal region TSP_3 PF02412.13 KFM02969.1 - 1.7e-57 190.5 129.2 2.4e-13 49.3 10.7 9.5 7 2 1 8 8 8 7 Thrombospondin type 3 repeat COMP PF11598.3 KFM02969.1 - 2.2e-20 72.4 2.6 5.2e-20 71.2 1.8 1.7 1 0 0 1 1 1 1 Cartilage oligomeric matrix protein EGF_CA PF07645.10 KFM02969.1 - 5.3e-13 48.7 41.0 4.2e-08 33.0 4.5 5.3 3 1 1 4 4 4 2 Calcium-binding EGF domain cEGF PF12662.2 KFM02969.1 - 4.5e-09 35.7 27.3 0.00012 21.6 0.3 5.1 4 0 0 4 4 4 3 Complement Clr-like EGF-like EGF PF00008.22 KFM02969.1 - 3.6e-06 26.8 0.7 3.6e-06 26.8 0.5 5.8 4 1 0 4 4 4 2 EGF-like domain EGF_3 PF12947.2 KFM02969.1 - 0.00048 20.0 53.4 0.00063 19.6 2.7 6.2 6 1 1 7 7 7 3 EGF domain hEGF PF12661.2 KFM02969.1 - 0.033 14.2 17.9 0.55 10.4 1.5 5.6 4 0 0 4 4 4 0 Human growth factor-like EGF Serinc PF03348.10 KFM02970.1 - 1.4e-139 465.5 32.4 1.5e-139 465.4 22.5 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF3593 PF12159.3 KFM02970.1 - 0.44 10.3 9.7 1.9 8.3 0.0 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3593) Pkinase PF00069.20 KFM02971.1 - 2.6e-71 239.8 0.0 2.9e-71 239.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM02971.1 - 1.1e-28 100.0 0.0 1.4e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM02971.1 - 2.9e-05 23.1 0.0 0.00014 20.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 KFM02971.1 - 8.3e-05 21.5 0.1 0.0012 17.7 0.1 2.1 2 0 0 2 2 2 1 Seadornavirus VP7 APH PF01636.18 KFM02971.1 - 0.0062 16.2 0.1 0.0099 15.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KFM02971.1 - 0.017 14.4 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 RIO1 family DUF2638 PF10937.3 KFM02972.1 - 0.01 16.8 0.1 0.01 16.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) CENP-H PF05837.7 KFM02973.1 - 1.1e-30 105.9 11.7 1.1e-30 105.9 8.1 2.3 2 1 0 2 2 2 1 Centromere protein H (CENP-H) AAA_3 PF07726.6 KFM02973.1 - 0.063 12.8 0.5 0.72 9.4 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1_C PF08438.5 KFM02973.1 - 2.5 8.3 6.5 4.2 7.6 3.8 1.9 1 1 0 1 1 1 0 GTPase of unknown function C-terminal I_LWEQ PF01608.12 KFM02973.1 - 3.6 7.5 13.0 5.6 6.8 9.0 1.4 1 1 0 1 1 1 0 I/LWEQ domain Cyclin_N PF00134.18 KFM02974.1 - 1.9e-46 156.7 0.2 4.5e-46 155.5 0.1 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFM02974.1 - 7.2e-32 109.7 1.9 8.2e-32 109.6 0.3 1.8 3 0 0 3 3 3 1 Cyclin, C-terminal domain Cation_efflux PF01545.16 KFM02975.1 - 2e-58 197.7 8.0 2e-58 197.7 5.5 3.1 2 1 0 2 2 2 1 Cation efflux family DUF2946 PF11162.3 KFM02975.1 - 0.00065 19.9 1.6 0.0026 17.9 1.1 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2946) RIIa PF02197.12 KFM02976.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit SH2 PF00017.19 KFM02977.1 - 1.2e-42 143.6 0.1 8.8e-22 76.7 0.0 2.6 2 0 0 2 2 2 2 SH2 domain RhoGAP PF00620.22 KFM02977.1 - 2.6e-31 108.2 2.4 3.2e-31 107.9 0.1 2.2 2 0 0 2 2 2 1 RhoGAP domain SH3_1 PF00018.23 KFM02977.1 - 9.2e-06 24.9 1.6 0.00052 19.3 0.1 2.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 KFM02977.1 - 0.00029 20.2 0.0 0.00085 18.7 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain DUF4201 PF13870.1 KFM02977.1 - 0.001 18.5 12.9 0.0055 16.1 1.4 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4201) SH3_9 PF14604.1 KFM02977.1 - 0.0022 17.5 0.7 0.0075 15.8 0.5 2.0 1 1 0 1 1 1 1 Variant SH3 domain Laminin_I PF06008.9 KFM02977.1 - 0.013 14.8 10.8 0.026 13.8 7.5 1.4 1 0 0 1 1 1 0 Laminin Domain I IncA PF04156.9 KFM02977.1 - 0.075 12.6 18.3 0.36 10.4 12.7 2.0 1 1 0 1 1 1 0 IncA protein DUF1338 PF07063.8 KFM02977.1 - 0.73 8.8 6.3 1.3 7.9 3.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1338) Rab5-bind PF09311.6 KFM02977.1 - 1.3 8.9 14.0 6 6.7 9.1 2.4 1 1 0 1 1 1 0 Rabaptin-like protein Troponin PF00992.15 KFM02977.1 - 2.9 7.9 16.9 2.8 7.9 10.6 1.8 1 1 1 2 2 2 0 Troponin V_ATPase_I PF01496.14 KFM02977.1 - 5.6 4.7 11.3 9.3 3.9 7.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1908 PF08926.6 KFM02979.1 - 2.5e-142 472.6 0.4 2.5e-142 472.6 0.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1908) Pkinase PF00069.20 KFM02979.1 - 6.5e-65 218.8 0.0 1.4e-64 217.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM02979.1 - 2.1e-27 95.8 0.0 4.1e-27 94.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PDZ PF00595.19 KFM02979.1 - 1.6e-09 37.8 0.0 3.5e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM02979.1 - 3e-07 30.2 0.1 7.2e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Kinase-like PF14531.1 KFM02979.1 - 2.9e-05 23.1 0.0 0.00021 20.3 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KFM02979.1 - 0.00012 21.9 0.0 0.035 13.8 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Tricorn_PDZ PF14685.1 KFM02979.1 - 0.048 13.4 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Tricorn protease PDZ domain RRM_6 PF14259.1 KFM02981.1 - 1.7e-14 53.5 0.0 3.2e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFM02981.1 - 5.2e-14 51.6 0.1 9.3e-14 50.8 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM02981.1 - 4.5e-09 36.0 0.0 7.1e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LRR_4 PF12799.2 KFM02982.1 - 4.2e-45 150.7 43.5 3.9e-08 32.7 1.5 9.9 4 3 8 12 12 12 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM02982.1 - 3.6e-42 141.9 26.2 8.8e-10 38.1 0.2 6.7 4 2 1 6 6 6 6 Leucine rich repeat LRR_1 PF00560.28 KFM02982.1 - 3.3e-24 81.1 33.3 0.075 13.1 0.1 16.2 16 0 0 16 16 16 7 Leucine Rich Repeat LRR_7 PF13504.1 KFM02982.1 - 8.2e-15 52.3 29.4 7.3 7.2 0.0 14.6 15 0 0 15 15 15 3 Leucine rich repeat PDZ PF00595.19 KFM02982.1 - 9e-13 48.2 0.1 2.2e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) LRR_5 PF13306.1 KFM02982.1 - 9.2e-06 25.3 4.9 0.011 15.4 0.2 3.9 2 1 1 4 4 4 2 Leucine rich repeats (6 copies) PDZ_2 PF13180.1 KFM02982.1 - 6.7e-05 22.7 0.2 0.0011 18.8 0.0 3.0 3 0 0 3 3 3 1 PDZ domain LRR_6 PF13516.1 KFM02982.1 - 0.0032 17.3 26.6 4.3 7.7 0.0 10.2 11 0 0 11 11 11 1 Leucine Rich repeat Peptidase_M3 PF01432.15 KFM02983.1 - 4.7e-153 510.5 0.1 6.5e-153 510.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 TPR_11 PF13414.1 KFM02984.1 - 4e-30 103.2 8.0 4.7e-22 77.4 2.7 2.6 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KFM02984.1 - 7.2e-29 98.1 10.2 5.5e-10 38.4 1.1 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFM02984.1 - 3.5e-23 79.5 6.4 1.8e-06 27.3 0.5 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFM02984.1 - 8.2e-16 56.8 5.7 2.1e-07 30.5 0.8 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFM02984.1 - 4.4e-15 54.2 1.1 0.00018 21.0 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFM02984.1 - 1.5e-13 50.9 0.5 8.4e-07 29.5 0.1 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFM02984.1 - 3.1e-11 42.2 7.9 0.00018 21.0 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFM02984.1 - 5.1e-11 42.3 3.4 2.3e-08 33.8 0.6 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFM02984.1 - 5.2e-11 42.1 0.0 0.011 16.3 0.0 3.9 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFM02984.1 - 1e-10 41.7 2.7 1.4e-06 28.5 0.1 2.9 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 KFM02984.1 - 4.8e-09 35.9 0.2 7.4e-06 25.7 0.1 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TOM20_plant PF06552.7 KFM02984.1 - 7.5e-06 25.6 1.5 0.0016 18.0 0.1 3.1 2 1 1 3 3 2 1 Plant specific mitochondrial import receptor subunit TOM20 Apc3 PF12895.2 KFM02984.1 - 2e-05 24.6 8.7 0.0016 18.5 2.1 2.4 2 1 1 3 3 2 2 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.4 KFM02984.1 - 4e-05 22.7 0.2 0.92 8.8 0.0 3.4 3 0 0 3 3 3 2 SHNi-TPR TPR_6 PF13174.1 KFM02984.1 - 0.00015 22.0 0.5 0.91 10.1 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 KFM02984.1 - 0.00022 21.0 5.0 0.38 10.6 0.2 3.6 2 1 1 3 3 3 2 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.1 KFM02984.1 - 0.00079 19.2 7.8 0.044 13.6 0.2 3.7 3 1 1 4 4 3 1 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.12 KFM02984.1 - 0.0033 17.7 0.2 0.02 15.1 0.0 2.1 1 1 1 2 2 2 1 Bacterial transcriptional activator domain Pectate_lyase_2 PF06917.7 KFM02984.1 - 0.0076 14.5 0.0 0.01 14.1 0.0 1.2 1 0 0 1 1 1 1 Periplasmic pectate lyase DUF627 PF04781.7 KFM02984.1 - 0.014 15.0 1.4 0.091 12.3 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF627) FAT PF02259.18 KFM02984.1 - 0.03 13.3 0.1 0.051 12.5 0.1 1.4 1 0 0 1 1 1 0 FAT domain DUF3856 PF12968.2 KFM02984.1 - 0.096 12.5 1.5 14 5.4 1.0 3.0 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) XPC-binding PF09280.6 KFM02984.1 - 0.6 9.6 15.4 0.8 9.2 2.3 2.7 3 0 0 3 3 3 0 XPC-binding domain DUF974 PF06159.8 KFM02985.1 - 1.1e-85 287.0 0.8 1.8e-85 286.3 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Transglut_C PF00927.17 KFM02985.1 - 0.002 18.1 0.5 0.13 12.2 0.0 3.0 3 0 0 3 3 3 1 Transglutaminase family, C-terminal ig like domain Trs65 PF12735.2 KFM02985.1 - 0.0051 16.1 0.4 0.87 8.8 0.0 3.3 3 1 1 4 4 4 1 TRAPP trafficking subunit Trs65 Arf PF00025.16 KFM02987.1 - 3.3e-71 238.1 0.4 8.4e-71 236.8 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family Ras PF00071.17 KFM02987.1 - 3.8e-12 45.8 0.0 7.4e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KFM02987.1 - 2.9e-11 42.8 0.0 5.6e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KFM02987.1 - 4.4e-09 35.5 0.4 1.7e-07 30.2 0.0 2.3 1 1 1 2 2 2 1 G-protein alpha subunit Miro PF08477.8 KFM02987.1 - 1.6e-08 35.0 0.2 5.2e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 KFM02987.1 - 1.9e-07 30.4 0.5 3.4e-07 29.6 0.0 1.6 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region zf-RING_5 PF14634.1 KFM02987.1 - 2e-06 27.4 2.1 2e-06 27.4 1.4 4.2 3 1 0 3 3 2 1 zinc-RING finger domain zf-B_box PF00643.19 KFM02987.1 - 3e-06 27.0 5.0 3e-06 27.0 3.4 3.9 4 0 0 4 4 3 2 B-box zinc finger zf-C3HC4 PF00097.20 KFM02987.1 - 0.0003 20.3 1.3 0.0003 20.3 0.9 3.8 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM02987.1 - 0.00056 19.6 4.1 0.00056 19.6 2.9 4.2 4 1 0 4 4 2 1 Ring finger domain MMR_HSR1 PF01926.18 KFM02987.1 - 0.00058 19.7 0.0 0.0043 16.9 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase zf-RING_UBOX PF13445.1 KFM02987.1 - 0.00061 19.4 2.9 0.00061 19.4 2.0 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 KFM02987.1 - 0.0015 18.5 3.6 0.0015 18.5 2.5 4.0 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFM02987.1 - 0.022 14.6 2.9 0.022 14.6 2.0 4.1 4 0 0 4 4 3 0 zinc finger of C3HC4-type, RING Pro_isomerase PF00160.16 KFM02988.1 - 2e-49 167.7 0.1 4.3e-49 166.7 0.1 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 KFM02988.1 - 4.4e-16 58.0 4.2 0.0041 16.9 0.0 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat CENP-K PF11802.3 KFM02989.1 - 1.2e-110 369.0 12.2 1.4e-110 368.7 8.5 1.0 1 0 0 1 1 1 1 Centromere-associated protein K Pox_G5 PF04599.7 KFM02989.1 - 0.013 14.2 7.0 0.033 12.8 4.3 1.8 1 1 1 2 2 2 0 Poxvirus G5 protein Innexin PF00876.13 KFM02989.1 - 0.024 13.7 0.1 0.035 13.2 0.1 1.3 1 0 0 1 1 1 0 Innexin DUF1409 PF07197.7 KFM02989.1 - 0.027 14.5 0.2 0.027 14.5 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1409) DUF2217 PF10265.4 KFM02989.1 - 0.058 12.1 4.4 0.072 11.8 3.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Helicase_C_4 PF13871.1 KFM02989.1 - 0.095 12.1 1.5 0.11 11.8 1.0 1.2 1 0 0 1 1 1 0 Helicase_C-like Occludin_ELL PF07303.8 KFM02989.1 - 0.16 12.7 11.2 7.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Occludin homology domain MIS13 PF08202.6 KFM02989.1 - 0.22 10.5 12.2 0.28 10.2 8.4 1.1 1 0 0 1 1 1 0 Mis12-Mtw1 protein family Syntaxin PF00804.20 KFM02989.1 - 0.38 10.9 9.8 4.5 7.4 6.9 2.1 1 1 0 1 1 1 0 Syntaxin CcdA PF07362.7 KFM02989.1 - 0.38 10.6 5.1 0.25 11.2 2.1 1.8 1 1 1 2 2 2 0 Post-segregation antitoxin CcdA Exonuc_VII_L PF02601.10 KFM02989.1 - 0.41 9.8 7.4 0.58 9.3 5.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2570 PF10828.3 KFM02989.1 - 1.6 8.3 7.7 3.2 7.3 5.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Phage_GP20 PF06810.6 KFM02989.1 - 4.2 6.7 14.9 0.28 10.5 7.0 1.4 2 0 0 2 2 2 0 Phage minor structural protein GP20 ADIP PF11559.3 KFM02989.1 - 5.9 6.7 15.3 2.4 8.0 7.6 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Pro_isomerase PF00160.16 KFM02990.1 - 5.3e-42 143.6 0.1 5.8e-42 143.5 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-CCHC_3 PF13917.1 KFM02991.1 - 4.9e-08 32.5 0.1 5.1e-08 32.5 0.1 1.3 1 1 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 KFM02991.1 - 0.12 12.3 3.3 0.17 11.8 2.3 1.2 1 0 0 1 1 1 0 Zinc knuckle Luteo_PO PF04662.8 KFM02991.1 - 0.13 11.6 0.0 0.15 11.4 0.0 1.0 1 0 0 1 1 1 0 Luteovirus P0 protein Occludin_ELL PF07303.8 KFM02992.1 - 0.11 13.2 0.1 0.38 11.5 0.0 1.8 2 0 0 2 2 2 0 Occludin homology domain zf-C3HC4_3 PF13920.1 KFM02993.1 - 6.9e-07 28.8 9.1 6.9e-07 28.8 6.3 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM02993.1 - 3.8e-06 26.4 12.1 3.8e-06 26.4 8.4 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM02993.1 - 4.3e-05 23.4 13.4 4.3e-05 23.4 9.3 3.7 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM02993.1 - 6.9e-05 22.5 12.6 6.9e-05 22.5 8.7 3.3 2 1 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KFM02993.1 - 0.00013 21.5 10.1 0.00013 21.5 7.0 3.6 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KFM02993.1 - 0.0076 15.9 6.3 0.039 13.6 4.4 2.3 1 0 0 1 1 1 1 RING-type zinc-finger DUF1639 PF07797.9 KFM02993.1 - 0.037 13.4 0.1 0.12 11.7 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1639) zf-RING_6 PF14835.1 KFM02993.1 - 1.1 9.1 21.5 0.11 12.2 2.7 3.3 3 0 0 3 3 3 0 zf-RING of BARD1-type protein 7tm_1 PF00001.16 KFM02994.1 - 7.1e-94 313.7 0.1 9e-94 313.3 0.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM02994.1 - 5.9e-13 48.5 6.2 2e-08 33.7 1.6 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM02994.1 - 2.9e-05 23.3 2.5 2.9e-05 23.3 1.8 2.2 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx IL13 PF03487.8 KFM02994.1 - 10 5.9 9.1 0.16 11.7 0.5 2.4 2 0 0 2 2 2 0 Interleukin-13 RrnaAD PF00398.15 KFM02995.1 - 4.3e-60 202.9 0.0 5.6e-60 202.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 KFM02995.1 - 3.3e-10 40.0 0.0 5.3e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFM02995.1 - 3.6e-07 30.7 0.0 6.6e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFM02995.1 - 1.1e-05 25.0 0.0 2.6e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFM02995.1 - 0.00024 20.5 0.0 0.00036 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 KFM02995.1 - 0.00032 20.2 0.0 0.00053 19.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 KFM02995.1 - 0.0017 18.1 0.0 0.003 17.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFM02995.1 - 0.0023 18.3 0.0 0.0043 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFM02995.1 - 0.0035 17.7 0.0 0.0065 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 KFM02995.1 - 0.0039 16.7 0.0 0.011 15.3 0.0 1.6 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 DREV PF05219.7 KFM02995.1 - 0.023 13.5 0.0 0.037 12.8 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_4 PF02390.12 KFM02995.1 - 0.028 13.4 0.0 0.043 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Met_10 PF02475.11 KFM02995.1 - 0.028 14.0 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Ubie_methyltran PF01209.13 KFM02995.1 - 0.03 13.4 0.0 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family tRNA_U5-meth_tr PF05958.6 KFM02995.1 - 0.081 11.6 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase CMAS PF02353.15 KFM02995.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Kinesin PF00225.18 KFM02996.1 - 5.5e-94 314.6 0.1 5.5e-94 314.6 0.1 1.7 2 0 0 2 2 2 1 Kinesin motor domain SWIM PF04434.12 KFM02998.1 - 0.071 12.6 3.4 0.18 11.3 2.4 1.7 1 0 0 1 1 1 0 SWIM zinc finger UPF0542 PF15086.1 KFM02999.1 - 2.6e-39 132.7 3.3 2.9e-39 132.6 2.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0542 7tm_1 PF00001.16 KFM02999.1 - 0.046 12.8 0.0 0.051 12.6 0.0 1.0 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) SieB PF14163.1 KFM02999.1 - 0.079 12.5 0.2 0.09 12.3 0.1 1.1 1 0 0 1 1 1 0 Superinfection exclusion protein B OAD_gamma PF04277.8 KFM02999.1 - 0.12 12.7 0.5 0.15 12.4 0.3 1.1 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain NDUFA12 PF05071.11 KFM03000.1 - 9.4e-06 26.0 1.6 9.4e-06 26.0 1.1 1.5 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 U3_snoRNA_assoc PF08297.6 KFM03000.1 - 0.011 15.9 0.6 0.015 15.5 0.4 1.2 1 0 0 1 1 1 0 U3 snoRNA associated DUF947 PF06102.7 KFM03000.1 - 0.012 15.4 1.6 0.014 15.2 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF947) AlaDh_PNT_C PF01262.16 KFM03000.1 - 0.064 12.8 0.4 0.088 12.3 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Gemini_AL3 PF01407.12 KFM03001.1 - 0.098 12.1 0.0 0.1 12.0 0.0 1.0 1 0 0 1 1 1 0 Geminivirus AL3 protein WD40 PF00400.27 KFM03002.1 - 5.3e-35 118.0 8.2 1.1e-09 37.7 0.1 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 KFM03002.1 - 0.0016 16.6 3.4 0.35 8.9 0.2 3.0 1 1 1 3 3 3 3 Nucleoporin Nup120/160 ELO PF01151.13 KFM03003.1 - 3.3e-61 206.7 26.3 3.8e-61 206.5 18.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DEP PF00610.16 KFM03004.1 - 1.1e-16 60.3 0.4 1.3e-15 56.8 0.0 2.6 3 0 0 3 3 3 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGAP PF00620.22 KFM03004.1 - 6.4e-07 29.0 0.3 2.9e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain DUF148 PF02520.12 KFM03004.1 - 0.023 14.4 0.2 0.082 12.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF148 TniB PF05621.6 KFM03004.1 - 0.071 11.8 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Ras PF00071.17 KFM03007.1 - 2.5e-61 205.8 2.2 3e-61 205.5 1.5 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM03007.1 - 9.7e-20 71.2 0.1 1.5e-19 70.6 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM03007.1 - 3.2e-14 52.5 0.3 4.5e-14 52.0 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KFM03007.1 - 4.3e-07 29.3 0.7 0.00018 20.8 0.0 2.1 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KFM03007.1 - 6.7e-06 25.4 0.6 9e-06 24.9 0.4 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFM03007.1 - 6.8e-05 22.3 0.1 0.00014 21.3 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KFM03007.1 - 0.0025 17.1 0.0 1.5 8.0 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B MMR_HSR1 PF01926.18 KFM03007.1 - 0.0031 17.4 0.1 0.0064 16.4 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase ORC3_N PF07034.6 KFM03007.1 - 0.0032 16.5 0.3 0.0041 16.1 0.2 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus G-alpha PF00503.15 KFM03007.1 - 0.011 14.4 1.4 3.3 6.2 0.0 3.4 2 2 2 4 4 4 0 G-protein alpha subunit Septin PF00735.13 KFM03007.1 - 0.014 14.4 0.2 0.64 8.9 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_14 PF13173.1 KFM03007.1 - 0.065 13.1 0.2 0.16 11.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.20 KFM03008.1 - 5.1e-69 232.3 0.0 9.6e-69 231.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain POLO_box PF00659.13 KFM03008.1 - 1.5e-38 130.5 2.3 2.8e-19 68.8 0.0 2.6 2 0 0 2 2 2 2 POLO box duplicated region Pkinase_Tyr PF07714.12 KFM03008.1 - 1.1e-36 126.2 0.0 1.8e-36 125.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM03008.1 - 1.1e-05 24.5 0.0 1.7e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Tcp10_C PF07202.8 KFM03008.1 - 0.042 13.3 0.1 0.47 9.9 0.1 2.1 1 1 0 1 1 1 0 T-complex protein 10 C-terminus APH PF01636.18 KFM03008.1 - 0.1 12.3 0.9 5.9 6.5 0.1 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Vasculin PF15337.1 KFM03010.1 - 2.3e-43 146.5 4.1 2.3e-43 146.5 2.9 2.7 3 0 0 3 3 3 1 Vascular protein family Vasculin-like 1 ELM2 PF01448.19 KFM03011.1 - 8.5e-16 58.3 0.3 3.1e-15 56.5 0.1 2.1 2 0 0 2 2 2 1 ELM2 domain Myb_DNA-binding PF00249.26 KFM03011.1 - 5.2e-06 26.4 0.2 1e-05 25.4 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain NEMO PF11577.3 KFM03011.1 - 0.03 14.0 0.4 0.081 12.6 0.3 1.7 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO SET PF00856.23 KFM03012.1 - 0.00012 22.3 0.2 0.00021 21.6 0.2 1.7 1 1 0 1 1 1 1 SET domain Pkinase PF00069.20 KFM03013.1 - 1.8e-69 233.8 0.0 1.3e-68 230.9 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM03013.1 - 4.5e-42 143.9 0.1 1.9e-40 138.5 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM03013.1 - 8.9e-10 37.9 0.4 1.3e-05 24.2 0.0 3.1 3 0 0 3 3 3 2 Kinase-like zf-RING_2 PF13639.1 KFM03013.1 - 0.00024 20.8 11.6 0.00072 19.3 8.0 1.9 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KFM03013.1 - 0.019 15.0 5.7 0.058 13.5 4.0 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger PHD PF00628.24 KFM03013.1 - 0.022 14.4 8.9 0.068 12.8 6.2 1.9 1 0 0 1 1 1 0 PHD-finger APH PF01636.18 KFM03013.1 - 0.063 12.9 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family FANCL_C PF11793.3 KFM03013.1 - 0.086 12.8 7.7 0.28 11.1 5.3 1.9 1 0 0 1 1 1 0 FANCL C-terminal domain zf-Apc11 PF12861.2 KFM03013.1 - 0.16 11.8 4.7 0.43 10.4 3.3 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Ank_2 PF12796.2 KFM03015.1 - 4.9e-47 158.2 9.7 2.6e-14 53.2 0.1 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KFM03015.1 - 1.6e-40 134.9 12.7 1.1e-07 31.3 0.0 8.6 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.1 KFM03015.1 - 1.2e-35 121.2 8.1 6.9e-09 35.9 0.0 7.0 2 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM03015.1 - 5.5e-35 118.5 13.8 4.6e-08 33.0 0.0 7.3 2 2 6 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM03015.1 - 5e-28 94.3 4.1 2.4e-05 24.1 0.0 9.1 9 0 0 9 9 9 6 Ankyrin repeat fn3 PF00041.16 KFM03016.1 - 2.8e-34 117.0 11.0 1.4e-09 37.9 0.4 5.6 5 0 0 5 5 5 4 Fibronectin type III domain Lep_receptor_Ig PF06328.6 KFM03016.1 - 1.4e-32 111.4 0.4 3e-32 110.3 0.3 1.6 1 0 0 1 1 1 1 Ig-like C2-type domain EpoR_lig-bind PF09067.5 KFM03016.1 - 3.9e-06 26.7 0.0 8.9e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Erythropoietin receptor, ligand binding IL6Ra-bind PF09240.5 KFM03016.1 - 1e-05 25.6 1.2 6.8e-05 22.9 0.1 2.5 2 0 0 2 2 2 1 Interleukin-6 receptor alpha chain, binding DUF4448 PF14610.1 KFM03016.1 - 0.012 15.1 1.1 0.19 11.1 0.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4448) DUF3377 PF11857.3 KFM03016.1 - 0.013 15.1 0.4 0.038 13.6 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Sarcoglycan_2 PF05510.8 KFM03016.1 - 0.058 11.6 0.0 0.12 10.7 0.0 1.4 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon Big_3_4 PF13754.1 KFM03016.1 - 0.36 11.1 4.5 1.2 9.5 0.1 3.5 2 1 1 3 3 3 0 Bacterial Ig-like domain (group 3) fn3 PF00041.16 KFM03017.1 - 9.5e-26 89.7 4.9 7.9e-10 38.7 0.1 4.2 4 0 0 4 4 4 3 Fibronectin type III domain Big_5 PF13205.1 KFM03017.1 - 0.0041 17.7 4.1 0.0052 17.3 0.2 2.5 1 1 1 2 2 2 1 Bacterial Ig-like domain Interfer-bind PF09294.5 KFM03017.1 - 0.043 13.8 0.1 7.9 6.5 0.0 3.1 3 0 0 3 3 3 0 Interferon-alpha/beta receptor, fibronectin type III MyTH4 PF00784.12 KFM03017.1 - 0.053 13.4 0.0 0.34 10.8 0.0 2.1 2 0 0 2 2 2 0 MyTH4 domain T2SG PF08334.6 KFM03017.1 - 0.07 12.8 0.8 1.6 8.5 0.1 2.5 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein G DEAD PF00270.24 KFM03018.1 - 5.9e-46 156.0 0.0 7e-45 152.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFM03018.1 - 2.2e-28 97.9 0.0 6.1e-28 96.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KFM03018.1 - 0.0002 20.2 0.0 0.00031 19.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KFM03018.1 - 0.0066 16.2 0.0 0.02 14.7 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 KFM03018.1 - 0.085 11.2 0.0 0.19 10.0 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1253) Aa_trans PF01490.13 KFM03019.1 - 1e-25 90.1 35.8 6.3e-15 54.5 6.1 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Pox_A14 PF05767.7 KFM03019.1 - 0.1 12.6 0.0 0.1 12.6 0.0 3.2 3 1 1 4 4 4 0 Poxvirus virion envelope protein A14 PAP2 PF01569.16 KFM03020.1 - 2.1e-22 79.1 2.7 2.1e-22 79.1 1.0 1.6 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 KFM03020.1 - 0.0051 17.0 2.9 0.0051 17.0 2.0 2.1 2 1 1 3 3 3 1 PAP2 superfamily C-terminal LrgB PF04172.11 KFM03020.1 - 0.023 13.8 0.1 0.047 12.8 0.0 1.5 1 0 0 1 1 1 0 LrgB-like family Polysacc_synt_C PF14667.1 KFM03020.1 - 4.4 7.0 8.0 0.42 10.3 1.1 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain HA2 PF04408.18 KFM03021.1 - 7.3e-18 64.4 0.1 7.3e-18 64.4 0.1 2.7 2 1 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KFM03021.1 - 6.6e-15 54.9 0.0 5.8e-14 51.8 0.0 2.6 2 1 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KFM03021.1 - 6.6e-11 41.9 0.2 1.6e-10 40.7 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFM03021.1 - 1.5e-09 37.6 0.0 3.6e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KFM03021.1 - 8.9e-06 25.8 1.0 1.7e-05 24.9 0.1 1.9 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 KFM03021.1 - 0.0036 16.2 0.1 0.0087 14.9 0.1 1.5 1 1 0 1 1 1 1 Type II/IV secretion system protein Zeta_toxin PF06414.7 KFM03021.1 - 0.014 14.5 0.7 0.51 9.4 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin ABC_tran PF00005.22 KFM03021.1 - 0.017 15.4 1.8 0.75 10.0 0.0 2.8 2 0 0 2 2 2 0 ABC transporter FtsK_SpoIIIE PF01580.13 KFM03021.1 - 0.035 13.5 0.0 0.077 12.4 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.1 KFM03021.1 - 0.054 13.0 0.1 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain GSHPx PF00255.14 KFM03022.1 - 1.9e-35 120.4 0.0 2.5e-35 120.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 KFM03022.1 - 1.6e-06 27.8 0.0 2.5e-06 27.1 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family SCO1-SenC PF02630.9 KFM03022.1 - 0.051 13.1 0.0 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 SCO1/SenC WD40 PF00400.27 KFM03023.1 - 7.1e-06 25.7 3.8 0.00024 20.8 0.0 3.2 3 1 0 3 3 3 2 WD domain, G-beta repeat Trypsin PF00089.21 KFM03024.1 - 1.8e-65 220.5 2.0 2.1e-65 220.4 1.4 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 KFM03024.1 - 3.1e-05 23.4 0.4 4.1e-05 22.9 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 KFM03024.1 - 0.0032 17.4 0.0 0.0064 16.4 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 KFM03026.1 - 5.3e-67 225.6 0.3 6e-67 225.4 0.2 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 KFM03026.1 - 2.1e-06 27.2 0.0 2.8e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 KFM03026.1 - 0.001 19.0 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain IGFBP PF00219.13 KFM03027.1 - 2.6e-05 24.6 21.2 2.6e-05 24.6 14.7 2.4 2 0 0 2 2 2 1 Insulin-like growth factor binding protein BAR_3_WASP_bdg PF10456.4 KFM03028.1 - 1.9e-114 380.8 6.5 2.6e-114 380.3 4.5 1.2 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein PX PF00787.19 KFM03028.1 - 8e-23 80.3 0.5 1.8e-22 79.2 0.0 1.8 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 KFM03028.1 - 0.0015 17.8 6.9 0.0024 17.1 1.6 2.3 2 0 0 2 2 2 2 Vps5 C terminal like HSP20 PF00011.16 KFM03029.1 - 4.9e-15 55.2 0.0 7.7e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Arf PF00025.16 KFM03030.1 - 1.3e-29 102.6 0.0 1.6e-29 102.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 KFM03030.1 - 4.3e-08 33.6 0.0 5.6e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 KFM03030.1 - 9.6e-07 28.1 0.0 1.2e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 KFM03030.1 - 1e-06 28.2 0.0 1.1e-06 28.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KFM03030.1 - 2.2e-05 23.6 0.0 2.6e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFM03030.1 - 3.7e-05 23.6 0.0 8.6e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 KFM03030.1 - 0.0018 17.0 0.9 0.024 13.3 0.0 2.0 1 1 1 2 2 2 1 G-protein alpha subunit AAA PF00004.24 KFM03030.1 - 0.0023 18.1 0.0 0.0035 17.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFM03030.1 - 0.0028 17.7 0.0 0.0041 17.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFM03030.1 - 0.011 15.5 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KFM03030.1 - 0.014 14.8 0.0 0.11 11.8 0.1 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 KFM03030.1 - 0.018 15.3 0.3 0.17 12.1 0.2 2.0 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.7 KFM03030.1 - 0.019 14.6 0.1 0.26 10.9 0.1 2.1 1 1 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 KFM03030.1 - 0.026 14.5 0.3 0.055 13.4 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 KFM03030.1 - 0.029 14.2 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 KFM03030.1 - 0.06 12.8 0.0 2.9 7.3 0.1 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 KFM03030.1 - 0.066 12.7 0.0 1.8 8.0 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 KFM03030.1 - 0.089 12.9 0.1 0.22 11.6 0.1 1.7 1 1 0 1 1 1 0 RNA helicase AAA_17 PF13207.1 KFM03030.1 - 0.12 13.1 0.1 0.14 12.9 0.0 1.3 1 1 0 1 1 1 0 AAA domain ETC_C1_NDUFA4 PF04800.7 KFM03031.1 - 2.7e-44 149.1 2.5 3.8e-44 148.6 1.8 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF2188 PF09954.4 KFM03031.1 - 0.016 15.0 0.1 0.046 13.6 0.0 1.9 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) Kazal_2 PF07648.10 KFM03032.1 - 1.6e-34 117.5 31.8 1.3e-13 50.6 1.1 5.0 4 1 0 4 4 4 3 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 KFM03032.1 - 6.7e-25 86.8 39.0 8.9e-10 38.4 5.3 4.1 3 1 0 3 3 3 3 Kazal-type serine protease inhibitor domain FOLN PF09289.5 KFM03032.1 - 1.3e-08 34.4 15.2 1.3e-08 34.4 10.5 4.7 4 1 0 4 4 4 2 Follistatin/Osteonectin-like EGF domain eRF1_1 PF03463.10 KFM03033.1 - 2.5e-49 166.2 0.1 4.4e-49 165.4 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 KFM03033.1 - 7.4e-36 123.4 0.0 1.2e-35 122.7 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 KFM03033.1 - 3.8e-26 91.5 0.1 1.1e-25 90.1 0.0 1.8 2 0 0 2 2 2 1 eRF1 domain 3 MethyTransf_Reg PF10119.4 KFM03033.1 - 0.008 16.6 0.1 0.051 14.0 0.0 2.4 2 1 1 3 3 3 1 Predicted methyltransferase regulatory domain Sec1 PF00995.18 KFM03034.1 - 5.9e-121 404.8 0.2 6.7e-121 404.6 0.1 1.0 1 0 0 1 1 1 1 Sec1 family PH PF00169.24 KFM03035.1 - 2.2e-10 40.6 0.7 2.2e-10 40.6 0.5 2.0 2 1 0 2 2 2 1 PH domain PH_9 PF15410.1 KFM03035.1 - 0.0017 18.4 1.9 0.012 15.7 0.4 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain LRR_4 PF12799.2 KFM03036.1 - 8.9e-16 57.1 13.9 1.9e-11 43.3 2.8 2.8 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM03036.1 - 9.9e-13 47.6 14.8 6.5e-09 35.4 2.7 2.7 1 1 2 3 3 3 3 Leucine rich repeat LRR_9 PF14580.1 KFM03036.1 - 3.5e-10 39.7 0.6 4.7e-10 39.3 0.4 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_7 PF13504.1 KFM03036.1 - 2e-08 33.0 9.9 0.062 13.5 0.1 5.4 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 KFM03036.1 - 4.6e-08 32.3 14.2 3.6e-05 23.3 0.2 4.5 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.28 KFM03036.1 - 1.8e-05 24.1 11.9 0.025 14.5 0.1 4.9 4 1 1 5 5 5 2 Leucine Rich Repeat BUD22 PF09073.5 KFM03036.1 - 6.7e-05 22.1 6.4 7.6e-05 21.9 4.4 1.1 1 0 0 1 1 1 1 BUD22 Aph-1 PF06105.7 KFM03037.1 - 3.7e-64 216.2 4.8 4e-64 216.1 3.3 1.0 1 0 0 1 1 1 1 Aph-1 protein DUF2324 PF10086.4 KFM03037.1 - 0.014 14.6 4.3 0.17 11.0 0.3 2.0 2 0 0 2 2 2 0 Putative membrane peptidase family (DUF2324) DUF4149 PF13664.1 KFM03037.1 - 1.2 9.2 9.0 0.42 10.7 0.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) DUF4131 PF13567.1 KFM03037.1 - 3 7.2 10.5 2.7 7.3 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) PRP3 PF08572.5 KFM03038.1 - 3.6e-43 147.5 10.2 1.7e-24 86.4 0.0 3.5 3 1 0 3 3 3 2 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 KFM03038.1 - 3.9e-42 142.9 0.9 3.9e-42 142.9 0.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) PWI PF01480.12 KFM03038.1 - 1.1e-16 60.6 0.0 2.8e-16 59.3 0.0 1.8 1 0 0 1 1 1 1 PWI domain CTD_bind PF04818.8 KFM03039.1 - 2.7e-20 72.3 1.5 3.7e-20 71.9 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase II-binding domain. Het-C PF07217.6 KFM03039.1 - 0.069 11.3 0.0 0.13 10.4 0.0 1.3 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Acetyltransf_11 PF13720.1 KFM03039.1 - 0.18 12.0 0.1 37 4.6 0.0 2.8 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DUF2356 PF10189.4 KFM03041.1 - 1.9e-76 256.1 3.0 2.8e-76 255.5 0.3 2.0 2 0 0 2 2 2 1 Conserved protein (DUF2356) Guanylate_cyc PF00211.15 KFM03042.1 - 8.8e-40 136.0 0.0 6.5e-38 129.9 0.0 2.1 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.9 KFM03042.1 - 1.3e-05 24.5 0.8 2e-05 23.9 0.6 1.3 1 0 0 1 1 1 1 Heme NO binding associated Pkinase_Tyr PF07714.12 KFM03042.1 - 0.00018 20.6 0.0 0.00034 19.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase dsDNA_bind PF01984.15 KFM03042.1 - 0.033 14.1 0.1 0.058 13.3 0.1 1.4 1 0 0 1 1 1 0 Double-stranded DNA-binding domain DIRP PF06584.8 KFM03042.1 - 0.076 12.8 0.3 0.13 12.1 0.2 1.3 1 0 0 1 1 1 0 DIRP Cnd1 PF12717.2 KFM03042.1 - 0.12 12.2 1.4 3.4 7.4 0.2 2.2 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DZF PF07528.9 KFM03043.1 - 5.5e-96 320.7 0.0 7.1e-96 320.3 0.0 1.1 1 0 0 1 1 1 1 DZF domain FoP_duplication PF13865.1 KFM03044.1 - 5e-21 74.9 1.7 5e-21 74.9 1.2 3.1 3 1 1 4 4 4 1 C-terminal duplication domain of Friend of PRMT1 Sbi-IV PF11621.3 KFM03044.1 - 1.2 9.3 10.2 7.6 6.7 0.0 3.8 2 2 2 4 4 4 0 C3 binding domain 4 of IgG-bind protein SBI S_100 PF01023.14 KFM03045.1 - 3.1e-21 74.3 1.6 4.7e-21 73.8 1.1 1.3 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_1 PF00036.27 KFM03045.1 - 2.4e-07 29.5 0.4 6.9e-06 25.0 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 KFM03045.1 - 2.2e-06 27.6 0.3 3.4e-06 27.0 0.2 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 KFM03045.1 - 9.3e-06 24.7 2.1 0.00038 19.6 0.1 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KFM03045.1 - 0.00019 21.0 0.1 0.22 11.5 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 KFM03045.1 - 0.0078 15.8 0.7 0.029 13.9 0.5 1.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_4 PF12763.2 KFM03045.1 - 0.049 13.3 0.0 0.057 13.1 0.0 1.2 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Feld-I_B PF09252.5 KFM03045.1 - 0.056 13.3 0.2 0.072 12.9 0.1 1.3 1 0 0 1 1 1 0 Allergen Fel d I-B chain S_100 PF01023.14 KFM03046.1 - 6.7e-13 47.7 0.1 1.1e-12 47.0 0.1 1.4 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain TPR_15 PF13429.1 KFM03046.1 - 0.033 13.2 0.0 0.041 12.9 0.0 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat EF-hand_7 PF13499.1 KFM03046.1 - 0.035 14.2 0.1 0.056 13.5 0.1 1.5 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.27 KFM03046.1 - 0.052 12.8 0.5 10 5.6 0.1 2.7 3 0 0 3 3 3 0 EF hand S_100 PF01023.14 KFM03047.1 - 6.4e-06 25.4 0.0 8.9e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_7 PF13499.1 KFM03048.1 - 1.3e-07 31.6 0.3 2.1e-07 30.9 0.1 1.4 2 0 0 2 2 2 1 EF-hand domain pair S_100 PF01023.14 KFM03048.1 - 3.4e-06 26.2 0.0 5.7e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_5 PF13202.1 KFM03048.1 - 6.8e-06 25.1 0.6 0.00015 20.9 0.1 2.3 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.27 KFM03048.1 - 9.4e-06 24.5 0.2 0.00083 18.4 0.1 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KFM03048.1 - 0.0053 16.3 1.2 0.034 13.7 0.6 2.2 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KFM03048.1 - 0.0059 16.3 0.0 0.56 10.2 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain S_100 PF01023.14 KFM03049.1 - 7.2e-17 60.4 0.8 1.1e-16 59.8 0.5 1.3 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_7 PF13499.1 KFM03049.1 - 0.00018 21.5 0.8 0.0003 20.8 0.5 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_4 PF12763.2 KFM03049.1 - 0.011 15.4 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 KFM03049.1 - 0.099 11.9 4.3 0.28 10.5 0.3 2.9 3 1 1 4 4 4 0 EF hand EF-hand_6 PF13405.1 KFM03049.1 - 0.23 11.4 5.7 1.7 8.7 0.2 3.1 1 1 1 3 3 3 0 EF-hand domain S_100 PF01023.14 KFM03050.1 - 2.9e-20 71.2 0.5 4.7e-20 70.6 0.3 1.4 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_1 PF00036.27 KFM03050.1 - 3.8e-05 22.6 0.2 0.0081 15.3 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 KFM03050.1 - 7.1e-05 22.8 0.2 9.1e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair NPL4 PF05021.10 KFM03050.1 - 0.021 13.9 0.2 0.023 13.8 0.1 1.1 1 0 0 1 1 1 0 NPL4 family EF-hand_4 PF12763.2 KFM03050.1 - 0.026 14.2 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand EF-hand_6 PF13405.1 KFM03050.1 - 0.063 13.1 0.0 14 5.9 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain MSC PF09402.5 KFM03050.1 - 0.066 11.9 0.2 0.064 11.9 0.1 1.0 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain DUF3837 PF12939.2 KFM03050.1 - 0.087 12.8 0.1 0.1 12.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3837) EF-hand_8 PF13833.1 KFM03050.1 - 0.12 12.0 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 EF-hand domain pair S_100 PF01023.14 KFM03051.1 - 8.3e-18 63.4 0.5 1.2e-17 62.9 0.4 1.2 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_1 PF00036.27 KFM03051.1 - 0.00031 19.8 1.2 0.00044 19.3 0.1 1.8 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 KFM03051.1 - 0.0013 18.8 0.6 0.0024 17.9 0.4 1.7 1 1 0 1 1 1 1 EF-hand domain pair DUF2513 PF10711.4 KFM03051.1 - 0.053 13.6 0.8 0.11 12.6 0.6 1.6 1 1 0 1 1 1 0 Hypothetical protein (DUF2513) Band_7 PF01145.20 KFM03051.1 - 5.5 6.8 8.0 15 5.4 5.5 1.6 1 1 0 1 1 1 0 SPFH domain / Band 7 family DUF2802 PF10975.3 KFM03051.1 - 5.7 6.7 10.6 31 4.4 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2802) Keratin PF02422.11 KFM03052.1 - 1.3e-31 108.4 11.9 1.4e-31 108.2 8.3 1.0 1 0 0 1 1 1 1 Keratin DUF3432 PF11914.3 KFM03052.1 - 0.15 12.0 5.8 0.2 11.6 3.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3432) Keratin PF02422.11 KFM03053.1 - 2.9e-35 120.1 11.7 3.2e-35 119.9 8.1 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 KFM03054.1 - 2.9e-35 120.1 11.7 3.2e-35 119.9 8.1 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 KFM03055.1 - 1.3e-34 118.0 12.5 1.6e-34 117.7 8.6 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 KFM03056.1 - 2.9e-35 120.1 11.7 3.2e-35 119.9 8.1 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 KFM03057.1 - 2.8e-20 72.0 5.9 2.9e-20 72.0 4.1 1.0 1 0 0 1 1 1 1 Keratin DUF3432 PF11914.3 KFM03057.1 - 0.031 14.3 2.7 0.034 14.1 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) TMEM171 PF15471.1 KFM03057.1 - 0.1 11.3 1.7 0.095 11.4 1.2 1.0 1 0 0 1 1 1 0 Transmembrane protein family 171 Keratin PF02422.11 KFM03058.1 - 1.1e-11 44.6 0.3 1.1e-11 44.5 0.2 1.1 1 0 0 1 1 1 1 Keratin Cystatin PF00031.16 KFM03059.1 - 4e-20 71.7 0.0 4.7e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Cystatin domain YmzC PF14157.1 KFM03059.1 - 0.018 14.8 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 YmzC-like protein Str_synth PF03088.11 KFM03060.1 - 2.8e-28 97.7 0.4 9.7e-28 96.0 0.1 2.1 2 1 1 3 3 3 1 Strictosidine synthase SGL PF08450.7 KFM03060.1 - 3.1e-13 49.6 0.0 4.8e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 KFM03060.1 - 0.00064 19.5 0.2 0.12 12.4 0.0 4.1 5 0 0 5 5 5 1 NHL repeat Arylesterase PF01731.15 KFM03060.1 - 0.0014 18.6 0.0 0.14 12.1 0.0 3.1 3 1 0 3 3 3 1 Arylesterase PQQ_2 PF13360.1 KFM03060.1 - 0.0051 16.3 0.0 1.5 8.2 0.0 2.4 2 1 0 2 2 2 2 PQQ-like domain PQQ_3 PF13570.1 KFM03060.1 - 0.12 12.7 0.8 2.9 8.3 0.0 3.2 4 1 0 4 4 4 0 PQQ-like domain AMP-binding PF00501.23 KFM03061.1 - 1.1e-95 320.5 0.1 1.3e-95 320.3 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFM03061.1 - 2.2e-20 73.3 2.3 3.2e-20 72.8 0.5 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Sugar_tr PF00083.19 KFM03062.1 - 6.9e-32 110.5 19.9 9.5e-32 110.1 13.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFM03062.1 - 2.9e-28 98.6 28.2 3.8e-28 98.2 19.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KFM03062.1 - 7.2 4.8 25.9 0.017 13.5 7.5 2.5 2 1 0 2 2 2 0 MFS/sugar transport protein TTL PF03133.10 KFM03063.1 - 1.1e-75 254.2 0.1 2.4e-75 253.1 0.0 1.5 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 KFM03063.1 - 3.6e-06 25.9 0.0 6.9e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATP-grasp_3 PF02655.9 KFM03063.1 - 0.1 12.4 0.0 1.5 8.7 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp domain CTD_bind PF04818.8 KFM03063.1 - 0.13 12.5 0.1 0.34 11.2 0.0 1.7 2 0 0 2 2 2 0 RNA polymerase II-binding domain. DUF2732 PF10809.3 KFM03063.1 - 0.34 10.4 1.2 1.4 8.4 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2732) RNA_pol_Rpb2_6 PF00562.23 KFM03064.1 - 3.6e-115 384.7 0.0 5e-115 384.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_3 PF04565.11 KFM03064.1 - 6.5e-24 83.4 0.0 1.5e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_1 PF04563.10 KFM03064.1 - 8.4e-20 70.5 0.1 1.6e-19 69.6 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpa2_4 PF06883.7 KFM03064.1 - 3.7e-19 68.4 0.0 8.7e-19 67.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 KFM03064.1 - 8e-19 67.6 0.0 2e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 KFM03064.1 - 1.2e-11 44.3 0.0 2e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_5 PF04567.12 KFM03064.1 - 0.002 18.0 0.0 0.0071 16.2 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 DUF3456 PF11938.3 KFM03065.1 - 7.4e-28 97.4 0.2 8.1e-28 97.3 0.1 1.0 1 0 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP Methyltransf_18 PF12847.2 KFM03066.1 - 0.00042 20.8 0.0 0.00073 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFM03066.1 - 0.00042 20.0 0.0 0.00055 19.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFM03066.1 - 0.00061 20.2 0.0 0.0011 19.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFM03066.1 - 0.0024 17.4 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFM03066.1 - 0.054 13.9 0.0 0.088 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 KFM03066.1 - 0.074 13.4 0.0 0.21 11.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain AAA PF00004.24 KFM03067.1 - 7.6e-67 223.5 0.0 5.1e-46 156.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFM03067.1 - 9.4e-09 35.4 1.3 0.0066 16.5 0.0 4.7 3 2 1 4 4 4 2 AAA domain AAA_19 PF13245.1 KFM03067.1 - 3.9e-08 32.9 0.1 0.00093 18.9 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain AAA_16 PF13191.1 KFM03067.1 - 1.1e-07 31.9 11.3 0.0057 16.6 0.3 4.2 2 2 1 4 4 4 2 AAA ATPase domain AAA_17 PF13207.1 KFM03067.1 - 1.3e-06 29.2 0.0 0.031 15.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KFM03067.1 - 1.7e-06 27.8 0.1 0.01 15.5 0.1 3.6 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KFM03067.1 - 5.4e-06 25.7 1.6 0.011 14.8 0.1 3.0 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KFM03067.1 - 0.00013 21.4 0.0 0.0043 16.4 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.9 KFM03067.1 - 0.0002 21.2 0.0 0.043 13.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.1 KFM03067.1 - 0.00024 21.1 0.0 0.33 10.9 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_33 PF13671.1 KFM03067.1 - 0.00024 21.0 0.0 0.034 14.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KFM03067.1 - 0.00037 20.6 0.0 0.021 14.9 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.1 KFM03067.1 - 0.00072 19.0 2.6 0.036 13.4 0.2 2.7 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.7 KFM03067.1 - 0.00092 18.3 0.0 0.0061 15.6 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Sigma54_activat PF00158.21 KFM03067.1 - 0.0032 16.9 0.0 2.5 7.5 0.0 2.9 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF815 PF05673.8 KFM03067.1 - 0.0033 16.4 0.0 0.42 9.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) TIP49 PF06068.8 KFM03067.1 - 0.0037 16.0 0.1 0.044 12.4 0.0 2.0 2 0 0 2 2 2 1 TIP49 C-terminus T2SE PF00437.15 KFM03067.1 - 0.0052 15.7 0.0 1.5 7.6 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_18 PF13238.1 KFM03067.1 - 0.0067 16.7 0.0 1 9.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 KFM03067.1 - 0.011 15.3 0.1 3.7 7.1 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 KFM03067.1 - 0.015 15.0 0.7 0.81 9.3 0.0 3.4 2 2 2 4 4 4 0 NACHT domain Vps4_C PF09336.5 KFM03067.1 - 0.015 15.1 0.0 0.071 13.0 0.0 2.2 2 0 0 2 2 1 0 Vps4 C terminal oligomerisation domain AAA_3 PF07726.6 KFM03067.1 - 0.017 14.7 0.0 0.75 9.4 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KFM03067.1 - 0.017 15.1 0.1 0.28 11.1 0.0 2.6 3 0 0 3 3 2 0 AAA domain PhoH PF02562.11 KFM03067.1 - 0.024 13.8 0.2 0.3 10.2 0.1 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_29 PF13555.1 KFM03067.1 - 0.031 13.8 0.8 2.2 7.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_24 PF13479.1 KFM03067.1 - 0.033 13.7 0.6 0.083 12.4 0.4 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KFM03067.1 - 0.068 12.8 0.1 2.5 7.8 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA_11 PF13086.1 KFM03067.1 - 0.077 12.5 0.0 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 KFM03067.1 - 0.1 11.4 0.0 0.2 10.5 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.1 KFM03067.1 - 0.13 11.8 0.1 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KFM03067.1 - 0.13 12.1 0.0 0.6 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 KFM03067.1 - 0.16 11.1 0.2 0.97 8.5 0.0 2.0 2 0 0 2 2 2 0 KaiC Homeobox PF00046.24 KFM03068.1 - 7.9e-24 83.0 3.1 1.4e-23 82.2 1.8 1.7 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 KFM03068.1 - 0.005 16.5 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain GDA1_CD39 PF01150.12 KFM03069.1 - 7.4e-73 245.4 0.0 1.9e-71 240.8 0.0 2.2 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 KFM03069.1 - 0.092 11.9 0.0 0.14 11.2 0.0 1.3 1 1 0 1 1 1 0 Ppx/GppA phosphatase family Phosphorylase PF00343.15 KFM03070.1 - 0 1210.5 0.0 0 1210.3 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Abhydrolase_5 PF12695.2 KFM03071.1 - 5.2e-19 68.4 0.0 1e-18 67.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFM03071.1 - 2.4e-17 63.5 0.1 7.4e-17 61.9 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFM03071.1 - 3e-09 36.7 0.3 4e-06 26.5 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KFM03071.1 - 8e-05 22.3 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KFM03071.1 - 0.00022 21.0 0.3 0.00042 20.0 0.2 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 KFM03071.1 - 0.002 17.3 0.0 0.0074 15.5 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KFM03071.1 - 0.006 16.0 0.0 0.03 13.7 0.0 2.1 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Thioesterase PF00975.15 KFM03071.1 - 0.0073 16.5 0.0 0.011 15.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain LIP PF03583.9 KFM03071.1 - 0.018 14.2 0.1 0.45 9.6 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase Peptidase_S15 PF02129.13 KFM03071.1 - 0.029 13.7 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF2424 PF10340.4 KFM03071.1 - 0.085 11.4 0.0 0.19 10.3 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) B56 PF01603.15 KFM03072.1 - 1.1e-176 587.4 6.2 1.4e-176 587.1 4.3 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Kelch_6 PF13964.1 KFM03073.1 - 1.2e-47 158.1 10.7 1.1e-10 41.1 0.1 6.2 5 1 1 6 6 6 5 Kelch motif Kelch_2 PF07646.10 KFM03073.1 - 3e-42 140.8 11.3 2.9e-07 29.9 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.20 KFM03073.1 - 6e-40 134.5 8.0 4.8e-07 29.2 0.0 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.1 KFM03073.1 - 9.6e-38 127.7 19.9 3.3e-08 33.1 0.3 7.8 6 3 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 KFM03073.1 - 3.7e-35 119.2 13.1 9e-09 35.2 0.2 7.3 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.1 KFM03073.1 - 7.2e-35 118.3 13.4 3.8e-07 29.9 0.0 6.4 6 1 0 6 6 6 6 Kelch motif Rax2 PF12768.2 KFM03073.1 - 0.016 14.3 0.0 1.7 7.7 0.0 2.1 2 0 0 2 2 2 0 Cortical protein marker for cell polarity DUF947 PF06102.7 KFM03074.1 - 1.3e-43 148.6 30.0 1.5e-43 148.5 20.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF947) CECR6_TMEM121 PF14997.1 KFM03075.1 - 2.2e-62 210.1 12.4 2.2e-62 210.1 8.6 1.5 2 0 0 2 2 2 1 CECR6/TMEM121 family EIID-AGA PF03613.9 KFM03075.1 - 0.00014 20.8 2.3 0.00022 20.2 1.6 1.3 1 0 0 1 1 1 1 PTS system mannose/fructose/sorbose family IID component Pacs-1 PF10254.4 KFM03076.1 - 2.8e-176 586.1 0.3 4e-176 585.6 0.2 1.2 1 0 0 1 1 1 1 PACS-1 cytosolic sorting protein Tubulin PF00091.20 KFM03077.1 - 9.7e-44 149.7 0.0 1.9e-43 148.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFM03077.1 - 3.6e-35 120.7 0.5 1.2e-30 106.1 0.1 2.4 1 1 1 2 2 2 2 Tubulin C-terminal domain Tubulin_3 PF14881.1 KFM03077.1 - 0.005 16.3 0.0 0.0087 15.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Se-cys_synth_N PF12390.3 KFM03078.1 - 0.19 11.8 1.6 0.48 10.5 0.4 2.3 2 0 0 2 2 2 0 Selenocysteine synthase N terminal DUF3652 PF12372.3 KFM03078.1 - 0.72 9.5 4.7 0.38 10.4 0.2 2.5 2 1 0 2 2 2 0 Huntingtin protein region Spond_N PF06468.8 KFM03080.1 - 1e-88 296.2 0.6 1.3e-88 295.8 0.4 1.1 1 0 0 1 1 1 1 Spondin_N TSP_1 PF00090.14 KFM03080.1 - 0.0075 16.3 3.8 0.014 15.4 2.7 1.5 1 0 0 1 1 1 1 Thrombospondin type 1 domain EMP24_GP25L PF01105.19 KFM03081.1 - 5.8e-45 153.2 0.4 6.4e-45 153.1 0.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF342 PF03961.8 KFM03081.1 - 0.019 13.3 0.2 0.025 13.0 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) zf-RING_5 PF14634.1 KFM03082.1 - 2.2e-09 36.8 15.6 4.3e-09 35.9 10.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Flp_N PF03930.9 KFM03082.1 - 0.003 17.2 0.6 0.0045 16.7 0.4 1.2 1 0 0 1 1 1 1 Recombinase Flp protein N-terminus zf-C3HC4_2 PF13923.1 KFM03082.1 - 0.0037 17.2 15.5 0.0047 16.9 9.8 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM03082.1 - 0.0084 15.7 12.1 0.0084 15.7 8.4 2.1 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFM03082.1 - 0.032 13.9 10.3 0.032 13.9 7.2 2.5 2 1 0 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.1 KFM03082.1 - 0.032 14.0 17.0 0.077 12.8 10.3 2.3 1 1 1 2 2 2 0 Ring finger domain zf-RING_6 PF14835.1 KFM03082.1 - 7.6 6.3 10.4 23 4.8 7.2 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Pex2_Pex12 PF04757.9 KFM03084.1 - 4.2e-36 124.4 6.7 6.2e-36 123.9 4.6 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.20 KFM03084.1 - 4.2e-08 32.7 8.8 4.2e-08 32.7 6.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM03084.1 - 0.0044 16.8 8.8 0.0044 16.8 6.1 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFM03084.1 - 0.0055 16.3 9.3 0.0099 15.5 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM03084.1 - 0.0066 16.4 10.5 0.0066 16.4 7.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFM03084.1 - 0.0076 16.0 11.5 0.019 14.8 8.0 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KFM03084.1 - 0.029 14.1 14.4 0.032 13.9 8.2 2.3 2 0 0 2 2 2 0 zinc-RING finger domain RDD PF06271.7 KFM03084.1 - 0.42 10.5 3.2 4.4 7.2 2.2 2.1 1 1 0 1 1 1 0 RDD family zf-RING_6 PF14835.1 KFM03084.1 - 0.53 10.1 4.3 1.5 8.6 2.6 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Homeobox PF00046.24 KFM03085.1 - 1.2e-67 223.3 20.5 7.7e-18 63.8 0.3 5.1 4 0 0 4 4 4 4 Homeobox domain Homeobox_KN PF05920.6 KFM03085.1 - 1.9e-13 49.8 1.3 0.016 14.8 0.0 4.8 4 0 0 4 4 4 3 Homeobox KN domain zf-C2H2 PF00096.21 KFM03085.1 - 5.6e-12 45.2 161.1 0.0045 17.2 0.2 22.3 24 0 0 24 24 23 12 Zinc finger, C2H2 type zf-met PF12874.2 KFM03085.1 - 7.5e-07 29.1 108.9 0.00033 20.7 0.6 16.3 18 0 0 18 18 18 8 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFM03085.1 - 0.00016 21.4 90.2 0.023 14.5 1.7 16.6 17 0 0 17 17 17 5 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KFM03085.1 - 0.00089 19.3 124.2 0.49 10.5 1.5 20.3 16 6 3 20 20 20 6 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.1 KFM03085.1 - 0.0018 18.4 125.9 0.0041 17.2 3.6 16.0 17 0 0 17 17 15 8 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 KFM03085.1 - 0.0046 17.1 140.9 0.2 12.0 0.6 21.0 22 1 0 22 22 22 10 C2H2-type zinc finger MerR_1 PF13411.1 KFM03085.1 - 0.008 15.9 0.2 0.058 13.1 0.0 2.6 3 0 0 3 3 3 1 MerR HTH family regulatory protein AKAP95 PF04988.7 KFM03085.1 - 0.088 12.5 0.1 0.088 12.5 0.0 14.7 15 1 1 16 16 16 0 A-kinase anchoring protein 95 (AKAP95) DUF3169 PF11368.3 KFM03085.1 - 6.6 5.8 0.9 12 4.9 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) Hormone_recep PF00104.25 KFM03087.1 - 1.6e-39 135.1 0.0 2.3e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFM03087.1 - 1.6e-30 105.1 17.8 2.7e-30 104.3 12.3 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Foamy_virus_ENV PF03408.9 KFM03087.1 - 0.074 10.5 1.4 0.098 10.1 1.0 1.1 1 0 0 1 1 1 0 Foamy virus envelope protein LCCL PF03815.14 KFM03088.1 - 1.2e-51 172.5 16.3 7.4e-27 93.1 0.4 3.2 3 0 0 3 3 3 2 LCCL domain CAP PF00188.21 KFM03088.1 - 3.2e-19 69.6 1.2 3.2e-19 69.6 0.8 1.8 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Rxt3 PF08642.5 KFM03088.1 - 0.0063 16.7 0.0 0.11 12.7 0.0 2.8 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 Yae1_N PF09811.4 KFM03089.1 - 1.4e-07 30.9 26.4 0.0038 16.7 14.8 2.9 2 1 0 2 2 2 1 Essential protein Yae1, N terminal CAP PF00188.21 KFM03090.1 - 5.1e-22 78.6 2.1 7.2e-22 78.1 1.5 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF3733 PF12534.3 KFM03090.1 - 0.25 10.6 1.7 4.4 6.6 0.0 2.6 2 0 0 2 2 2 0 Leucine-rich repeat containing protein 8 GST_N_3 PF13417.1 KFM03091.1 - 6.3e-12 45.5 0.0 1.2e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFM03091.1 - 1.1e-09 37.9 0.0 2.3e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KFM03091.1 - 1.5e-09 37.8 0.0 3.1e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFM03091.1 - 3.6e-08 33.2 0.0 7.4e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFM03091.1 - 8e-08 32.1 0.1 2.2e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFM03091.1 - 0.00012 22.4 0.1 0.00028 21.3 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF3206 PF11472.3 KFM03091.1 - 0.025 14.3 0.1 0.043 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3206) DUF1617 PF07761.7 KFM03091.1 - 0.031 14.3 1.4 0.059 13.4 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1617) DUF2096 PF09869.4 KFM03091.1 - 0.032 14.1 2.3 0.29 10.9 0.2 2.5 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2096) Med30 PF11315.3 KFM03091.1 - 0.042 13.9 2.7 0.22 11.6 1.9 2.0 1 1 0 1 1 1 0 Mediator complex subunit 30 MtrG PF04210.8 KFM03091.1 - 0.1 12.2 0.6 0.26 10.9 0.4 1.7 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G MCR_C PF04609.7 KFM03091.1 - 0.13 11.0 0.2 0.19 10.4 0.1 1.3 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein C E1_DerP2_DerF2 PF02221.10 KFM03092.1 - 5.1e-07 29.9 0.0 5.9e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 ML domain DUF1301 PF06979.7 KFM03093.1 - 1.1e-65 219.8 8.8 1.3e-65 219.5 6.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1301) Skp1_POZ PF03931.10 KFM03094.1 - 1.7e-23 82.5 0.0 2.4e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain UQ_con PF00179.21 KFM03095.1 - 3.7e-34 117.1 0.2 4e-34 117.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFM03095.1 - 2.8e-05 23.8 0.0 3.7e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 KFM03095.1 - 0.0078 15.8 0.0 0.0098 15.5 0.0 1.2 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 KFM03095.1 - 0.016 15.1 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 RWD domain dsrm PF00035.20 KFM03096.1 - 5e-52 174.3 2.7 1.1e-13 51.4 0.0 4.9 4 0 0 4 4 4 4 Double-stranded RNA binding motif DND1_DSRM PF14709.1 KFM03096.1 - 7.9e-11 42.0 1.9 0.0021 18.2 0.0 5.0 4 1 0 4 4 4 3 double strand RNA binding domain from DEAD END PROTEIN 1 Ribosomal_L30_N PF08079.7 KFM03097.1 - 4.6e-25 87.4 16.6 8.6e-25 86.5 11.5 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 KFM03097.1 - 6.8e-22 76.7 0.9 1.6e-21 75.5 0.6 1.7 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e TSP_1 PF00090.14 KFM03098.1 - 0.00037 20.5 2.1 0.00037 20.5 1.4 2.7 3 1 0 3 3 3 1 Thrombospondin type 1 domain Ank_2 PF12796.2 KFM03100.1 - 1.1e-91 301.3 17.8 7.8e-16 58.1 0.0 8.3 3 2 5 8 8 8 7 Ankyrin repeats (3 copies) Ank PF00023.25 KFM03100.1 - 3.4e-85 275.8 21.4 2.5e-09 36.4 0.0 15.0 15 0 0 15 15 15 14 Ankyrin repeat Ank_3 PF13606.1 KFM03100.1 - 1.2e-68 220.1 21.9 6.8e-06 25.8 0.0 16.3 16 0 0 16 16 16 13 Ankyrin repeat Ank_4 PF13637.1 KFM03100.1 - 8.1e-65 214.1 14.3 7.6e-10 39.0 0.1 10.2 6 3 6 12 12 12 10 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM03100.1 - 1.2e-62 206.4 13.7 4.6e-08 33.0 0.0 13.4 3 3 10 13 13 13 13 Ankyrin repeats (many copies) Ion_trans PF00520.26 KFM03100.1 - 1.3e-08 34.3 24.5 2.5e-08 33.3 17.0 1.5 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.7 KFM03100.1 - 4.3e-05 22.1 18.5 0.0047 15.4 8.0 2.2 1 1 1 2 2 2 2 Polycystin cation channel DUF1843 PF08898.5 KFM03100.1 - 0.14 12.2 0.4 10 6.2 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) Myosin_tail_1 PF01576.14 KFM03104.1 - 0.0012 16.6 18.4 0.0012 16.6 12.8 3.0 2 1 1 3 3 3 1 Myosin tail Macoilin PF09726.4 KFM03104.1 - 0.086 11.1 29.1 0.14 10.4 20.2 1.3 1 0 0 1 1 1 0 Transmembrane protein DUF3027 PF11228.3 KFM03104.1 - 0.17 11.5 1.1 0.27 10.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3027) CheY-binding PF09078.6 KFM03104.1 - 7.8 6.5 10.5 1.8 8.6 0.2 3.3 4 0 0 4 4 4 0 CheY binding RFX_DNA_binding PF02257.10 KFM03105.1 - 2.4e-33 114.1 0.0 1.1e-32 112.0 0.0 2.1 2 0 0 2 2 2 1 RFX DNA-binding domain Pox_D5 PF03288.11 KFM03105.1 - 0.0001 22.4 0.1 0.00026 21.1 0.1 1.6 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.6 KFM03105.1 - 0.034 13.8 0.0 0.093 12.4 0.0 1.7 1 0 0 1 1 1 0 CDC6, C terminal HECT PF00632.20 KFM03106.1 - 1.2e-94 317.1 0.1 1.7e-94 316.5 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 KFM03106.1 - 6.7e-46 153.7 25.8 2.9e-13 49.4 0.4 5.4 5 0 0 5 5 5 4 WW domain C2 PF00168.25 KFM03106.1 - 6.3e-12 45.1 0.1 1.4e-11 44.1 0.1 1.6 1 0 0 1 1 1 1 C2 domain Trp_Tyr_perm PF03222.8 KFM03106.1 - 0.4 9.4 0.1 0.58 8.9 0.0 1.1 1 0 0 1 1 1 0 Tryptophan/tyrosine permease family fn3 PF00041.16 KFM03107.1 - 2.9e-62 206.8 4.5 1.4e-11 44.3 0.0 5.6 5 0 0 5 5 5 5 Fibronectin type III domain I-set PF07679.11 KFM03107.1 - 1.9e-56 187.9 0.0 2.7e-15 56.0 0.0 5.7 5 0 0 5 5 5 4 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM03107.1 - 3.4e-36 123.2 0.1 4.5e-08 33.1 0.0 5.2 5 0 0 5 5 5 4 Immunoglobulin domain Ig_3 PF13927.1 KFM03107.1 - 4.9e-30 103.8 0.6 9.6e-08 32.4 0.0 6.0 6 0 0 6 6 6 4 Immunoglobulin domain ig PF00047.20 KFM03107.1 - 4e-23 81.2 0.0 0.00029 20.8 0.0 5.5 5 1 0 5 5 5 4 Immunoglobulin domain V-set PF07686.12 KFM03107.1 - 1.5e-18 66.7 0.1 0.0022 17.8 0.0 6.1 4 3 0 4 4 4 4 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM03107.1 - 1.1e-10 41.2 0.6 0.17 11.8 0.0 4.7 4 0 0 4 4 4 3 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.11 KFM03107.1 - 7e-07 27.8 0.1 0.27 9.4 0.0 3.5 2 1 1 3 3 3 3 Alphaherpesvirus glycoprotein E C1-set PF07654.10 KFM03107.1 - 0.00089 19.2 0.5 0.46 10.5 0.0 4.5 4 1 0 4 4 4 1 Immunoglobulin C1-set domain Adeno_E3_CR2 PF02439.10 KFM03107.1 - 0.014 14.9 5.2 0.031 13.8 3.6 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.15 KFM03107.1 - 0.07 12.7 0.2 0.49 10.0 0.3 2.2 2 0 0 2 2 2 0 Syndecan domain PHD PF00628.24 KFM03108.1 - 6.3e-07 28.9 5.9 1.1e-06 28.2 4.1 1.4 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 KFM03108.1 - 0.0076 15.9 2.8 0.0076 15.9 1.9 1.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 DUF1498 PF07385.7 KFM03108.1 - 0.096 11.8 0.6 0.15 11.1 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1498) zf-RING_2 PF13639.1 KFM03108.1 - 0.17 11.6 4.5 0.31 10.9 3.1 1.5 1 0 0 1 1 1 0 Ring finger domain FANCL_C PF11793.3 KFM03108.1 - 1.4 8.9 5.1 0.86 9.6 1.9 1.8 2 0 0 2 2 2 0 FANCL C-terminal domain TPR_11 PF13414.1 KFM03109.1 - 1.8e-16 59.4 5.7 6.1e-11 41.8 1.9 2.5 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KFM03109.1 - 1.7e-13 49.5 4.1 5e-06 25.8 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFM03109.1 - 3.3e-10 39.0 3.9 0.001 18.8 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat CS PF04969.11 KFM03109.1 - 4.8e-10 39.8 0.0 3.9e-09 36.9 0.0 2.5 3 0 0 3 3 2 1 CS domain TPR_9 PF13371.1 KFM03109.1 - 2.4e-07 30.5 3.4 0.0055 16.5 0.2 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFM03109.1 - 5.4e-07 29.4 1.1 3e-06 27.0 0.1 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFM03109.1 - 6.1e-05 22.5 2.7 4.7 7.2 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFM03109.1 - 0.0016 19.0 3.3 0.054 14.1 0.8 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFM03109.1 - 0.0072 16.8 0.6 2.6 8.9 0.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat AAA_13 PF13166.1 KFM03109.1 - 0.28 9.5 22.0 0.43 8.9 15.2 1.2 1 0 0 1 1 1 0 AAA domain Asp-B-Hydro_N PF05279.6 KFM03109.1 - 3.4 7.4 25.4 5.6 6.7 17.6 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region LMBR1 PF04791.11 KFM03109.1 - 6.2 5.2 7.7 8.2 4.8 5.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4613 PF15390.1 KFM03109.1 - 8.9 4.3 12.6 13 3.8 8.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Fib_alpha PF08702.5 KFM03110.1 - 0.0049 17.0 7.8 0.0049 17.0 5.4 5.0 2 1 2 5 5 5 1 Fibrinogen alpha/beta chain family DUF3243 PF11588.3 KFM03110.1 - 0.013 15.5 3.3 0.038 13.9 0.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3243) DUF1664 PF07889.7 KFM03110.1 - 0.55 10.0 27.4 1.5 8.6 3.0 4.3 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) JSRP PF15312.1 KFM03110.1 - 0.81 9.6 0.0 0.81 9.6 0.0 2.7 3 1 0 3 3 3 0 Junctional sarcoplasmic reticulum protein FUSC PF04632.7 KFM03110.1 - 7.4 4.8 5.8 11 4.2 4.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF641 PF04859.7 KFM03110.1 - 8.9 6.0 30.5 3.2 7.5 5.8 4.3 1 1 1 3 3 3 0 Plant protein of unknown function (DUF641) Glyco_transf_22 PF03901.12 KFM03111.1 - 8.5e-95 318.2 26.2 9.9e-95 317.9 18.2 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Ras PF00071.17 KFM03112.1 - 2.1e-57 193.0 0.0 2.5e-57 192.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM03112.1 - 1.8e-16 60.7 0.0 2.9e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM03112.1 - 1e-11 44.4 0.0 1.4e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFM03112.1 - 4.7e-05 22.8 0.0 8.1e-05 22.1 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFM03112.1 - 0.0011 18.9 0.0 0.0018 18.2 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KFM03112.1 - 0.024 13.8 0.0 0.38 9.9 0.0 2.2 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KFM03112.1 - 0.026 13.6 0.3 0.17 10.9 0.2 2.0 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 KFM03112.1 - 0.083 13.0 0.0 0.19 11.8 0.0 1.7 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 KFM03112.1 - 0.12 11.9 0.2 0.26 10.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain Ribosomal_L24e PF01246.15 KFM03113.1 - 1.1e-12 47.5 5.6 1.1e-12 47.5 3.9 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e DDE_Tnp_1_4 PF13701.1 KFM03113.1 - 0.028 12.6 2.1 0.03 12.5 1.5 1.1 1 0 0 1 1 1 0 Transposase DDE domain group 1 Paf67 PF10255.4 KFM03113.1 - 0.66 8.7 4.8 0.7 8.7 0.4 1.9 1 1 1 2 2 2 0 RNA polymerase I-associated factor PAF67 Muted PF14942.1 KFM03113.1 - 9.5 6.0 12.4 4 7.3 0.5 2.4 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein MutS_V PF00488.16 KFM03114.1 - 1.9e-84 282.7 0.0 2.9e-84 282.1 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KFM03114.1 - 4.5e-46 157.2 0.0 7.1e-46 156.5 0.0 1.3 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KFM03114.1 - 8.6e-34 115.9 0.2 2.3e-33 114.6 0.1 1.8 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.13 KFM03114.1 - 4.7e-19 68.3 0.7 1.8e-18 66.4 0.2 2.3 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.12 KFM03114.1 - 6.9e-13 48.8 2.3 2.9e-12 46.8 0.1 2.9 2 1 0 2 2 2 1 MutS domain II Plasmid_RAQPRD PF09686.5 KFM03114.1 - 0.098 12.7 0.4 0.44 10.6 0.0 2.2 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Beta_helix PF13229.1 KFM03115.1 - 7.1e-99 328.0 94.0 7.5e-26 90.7 7.5 4.6 1 1 4 5 5 5 5 Right handed beta helix region NosD PF05048.8 KFM03115.1 - 1.3e-49 168.4 59.2 4.9e-17 61.8 5.0 4.8 1 1 5 6 6 6 6 Periplasmic copper-binding protein (NosD) F-box-like PF12937.2 KFM03115.1 - 2.7e-16 59.0 0.3 5.7e-16 57.9 0.2 1.5 1 0 0 1 1 1 1 F-box-like zf-UBR PF02207.15 KFM03115.1 - 3.9e-12 45.7 12.7 3.9e-12 45.7 8.8 1.9 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) F-box PF00646.28 KFM03115.1 - 7e-08 31.9 0.3 7e-08 31.9 0.2 1.8 2 0 0 2 2 2 1 F-box domain TFIIA PF03153.8 KFM03116.1 - 7.3e-88 295.9 30.0 4.2e-87 293.4 20.8 2.2 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Adap_comp_sub PF00928.16 KFM03116.1 - 1.7e-57 194.5 0.9 2.7e-57 193.8 0.6 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family 7tm_1 PF00001.16 KFM03117.1 - 3.6e-39 134.4 21.8 4.9e-39 134.0 15.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_8 PF13855.1 KFM03117.1 - 1.6e-18 66.1 7.1 2.4e-05 23.9 1.5 4.5 2 2 2 4 4 4 4 Leucine rich repeat LRR_5 PF13306.1 KFM03117.1 - 3.5e-11 42.8 0.1 6.5e-05 22.6 0.0 2.5 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_4 PF12799.2 KFM03117.1 - 0.0023 17.4 8.0 0.46 10.1 0.0 4.3 3 2 0 3 3 3 2 Leucine Rich repeats (2 copies) GnHR_trans PF12369.3 KFM03117.1 - 0.0027 18.1 3.0 0.0027 18.1 2.1 2.0 2 1 0 2 2 2 1 Gonadotropin hormone receptor transmembrane region LRR_1 PF00560.28 KFM03117.1 - 0.91 9.7 8.3 45 4.6 0.0 6.1 7 1 0 7 7 7 0 Leucine Rich Repeat 7tm_1 PF00001.16 KFM03119.1 - 7.3e-40 136.7 28.1 1e-39 136.2 19.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GnHR_trans PF12369.3 KFM03119.1 - 3.3e-24 85.1 0.4 1.6e-23 82.9 0.2 2.2 2 0 0 2 2 2 1 Gonadotropin hormone receptor transmembrane region LRR_8 PF13855.1 KFM03119.1 - 1.5e-11 43.9 15.6 1.3e-05 24.8 0.5 3.0 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 KFM03119.1 - 0.00022 20.8 5.8 0.054 13.5 0.1 5.0 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_4 PF12799.2 KFM03119.1 - 0.00083 18.9 7.5 0.015 14.8 1.0 3.1 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 KFM03119.1 - 0.26 11.6 1.1 11 6.7 0.3 3.5 3 0 0 3 3 3 0 Leucine rich repeat Laminin_G_2 PF02210.19 KFM03120.1 - 1.7e-131 432.2 10.7 6.8e-30 103.7 0.0 5.2 5 0 0 5 5 5 5 Laminin G domain Laminin_G_1 PF00054.18 KFM03120.1 - 3.4e-87 289.1 4.6 8.4e-25 87.2 0.0 6.5 5 1 0 5 5 5 5 Laminin G domain Laminin_G_3 PF13385.1 KFM03120.1 - 2.4e-19 70.1 3.9 0.00057 20.1 0.0 5.3 5 0 0 5 5 5 5 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.22 KFM03120.1 - 5.1e-08 32.7 18.4 0.00017 21.4 5.3 2.7 2 0 0 2 2 2 2 EGF-like domain DUF1080 PF06439.6 KFM03120.1 - 0.0019 18.1 0.0 5.9 6.7 0.0 3.6 3 0 0 3 3 3 1 Domain of Unknown Function (DUF1080) NGF PF00243.13 KFM03121.1 - 3.2e-60 200.9 2.2 5.2e-60 200.3 1.5 1.3 1 0 0 1 1 1 1 Nerve growth factor family DUF1857 PF08982.6 KFM03121.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1857) Tetraspannin PF00335.15 KFM03123.1 - 3.4e-35 121.3 10.6 4.1e-35 121.0 7.4 1.1 1 0 0 1 1 1 1 Tetraspanin family Claudin_2 PF13903.1 KFM03123.1 - 0.045 13.4 4.2 0.04 13.6 0.7 2.1 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF2650 PF10853.3 KFM03123.1 - 0.31 10.5 3.9 6.1 6.3 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2650) CD20 PF04103.10 KFM03123.1 - 0.64 9.9 8.5 2 8.3 5.9 1.8 1 1 0 1 1 1 0 CD20-like family Cys_knot PF00007.17 KFM03124.1 - 2.2e-30 104.8 14.5 2.7e-30 104.5 10.0 1.1 1 0 0 1 1 1 1 Cystine-knot domain DUF837 PF05769.6 KFM03125.1 - 3.2e-37 127.8 7.5 3.6e-37 127.6 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF837) Herpes_BLRF2 PF05812.7 KFM03125.1 - 0.024 14.4 1.0 0.024 14.4 0.7 1.6 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein CRC_subunit PF08624.5 KFM03125.1 - 0.061 13.2 0.4 0.087 12.7 0.1 1.3 2 0 0 2 2 2 0 Chromatin remodelling complex Rsc7/Swp82 subunit DUF4349 PF14257.1 KFM03125.1 - 0.13 11.4 1.1 0.16 11.1 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Stathmin PF00836.14 KFM03125.1 - 0.31 10.6 5.2 0.42 10.2 3.6 1.3 1 1 0 1 1 1 0 Stathmin family DUF972 PF06156.8 KFM03125.1 - 1.4 9.3 6.3 0.98 9.8 1.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Atg14 PF10186.4 KFM03125.1 - 1.4 7.8 4.5 1.6 7.5 3.1 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Rab5-bind PF09311.6 KFM03125.1 - 9.6 6.0 11.7 2.8 7.8 2.6 2.3 1 1 1 2 2 2 0 Rabaptin-like protein Ras PF00071.17 KFM03126.1 - 6.1e-58 194.7 0.1 7.1e-58 194.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM03126.1 - 1.2e-19 70.9 0.0 1.7e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM03126.1 - 4.7e-08 32.4 0.0 5.7e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFM03126.1 - 6.2e-08 32.2 0.1 2.9e-07 30.1 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFM03126.1 - 1.1e-05 25.3 0.0 1.6e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFM03126.1 - 0.001 18.3 0.1 0.0058 15.9 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.7 KFM03126.1 - 0.027 13.5 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF2075 PF09848.4 KFM03126.1 - 0.03 13.2 0.0 1.2 8.0 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 KFM03126.1 - 0.038 14.8 0.8 12 6.6 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KFM03126.1 - 0.049 13.0 0.0 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KFM03126.1 - 0.073 13.2 0.1 1.6 8.8 0.1 2.5 1 1 1 2 2 2 0 AAA domain DUF258 PF03193.11 KFM03126.1 - 0.082 12.0 0.1 0.099 11.8 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 KFM03126.1 - 0.13 11.7 0.5 3.8 6.9 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein A_deaminase PF00962.17 KFM03127.1 - 2e-120 401.6 1.0 3.6e-120 400.8 0.7 1.4 1 0 0 1 1 1 1 Adenosine/AMP deaminase DENN PF02141.16 KFM03128.1 - 4.7e-60 202.4 0.7 8.6e-60 201.6 0.5 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 KFM03128.1 - 1.4e-20 72.9 1.3 2.8e-20 72.0 0.9 1.5 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.14 KFM03128.1 - 3e-19 68.8 5.2 6.9e-19 67.6 3.6 1.7 1 0 0 1 1 1 1 dDENN domain BCAS2 PF05700.6 KFM03129.1 - 3.3e-45 154.2 16.7 3.9e-45 154.0 11.6 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) THOC7 PF05615.8 KFM03129.1 - 7.7e-06 26.2 11.9 1.7e-05 25.1 2.4 2.1 1 1 1 2 2 2 1 Tho complex subunit 7 EzrA PF06160.7 KFM03129.1 - 0.00025 19.3 8.2 0.0017 16.6 5.7 1.8 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA Filament PF00038.16 KFM03129.1 - 0.0011 18.5 11.3 0.0013 18.2 7.8 1.1 1 0 0 1 1 1 1 Intermediate filament protein DUF4201 PF13870.1 KFM03129.1 - 0.0028 17.1 9.8 0.079 12.3 5.2 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4201) Transcrip_act PF04949.8 KFM03129.1 - 0.034 13.7 0.9 0.042 13.4 0.6 1.3 1 0 0 1 1 1 0 Transcriptional activator CENP-F_leu_zip PF10473.4 KFM03129.1 - 0.062 13.1 10.8 0.14 12.0 7.6 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Phlebovirus_NSM PF07246.6 KFM03129.1 - 0.098 11.7 6.3 0.13 11.4 4.3 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DivIC PF04977.10 KFM03129.1 - 0.22 11.0 12.2 0.62 9.5 0.8 2.5 3 0 0 3 3 2 0 Septum formation initiator Spc24 PF08286.6 KFM03129.1 - 0.22 11.2 12.3 0.24 11.0 1.2 2.6 1 1 1 3 3 3 0 Spc24 subunit of Ndc80 DUF724 PF05266.9 KFM03129.1 - 0.23 11.0 10.4 1.4 8.5 7.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF724) FlaC_arch PF05377.6 KFM03129.1 - 0.24 11.3 8.2 0.37 10.6 0.3 2.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Tropomyosin_1 PF12718.2 KFM03129.1 - 0.31 10.8 11.1 0.32 10.8 1.8 2.2 1 1 1 2 2 2 0 Tropomyosin like TPR_MLP1_2 PF07926.7 KFM03129.1 - 0.34 10.6 14.6 1.5 8.5 10.1 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Cep57_MT_bd PF06657.8 KFM03129.1 - 0.36 10.8 7.0 12 5.8 0.1 2.8 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DUF3450 PF11932.3 KFM03129.1 - 0.36 10.0 13.2 0.047 12.9 4.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) CENP-H PF05837.7 KFM03129.1 - 0.38 10.9 12.1 1 9.6 6.0 2.4 2 1 1 3 3 2 0 Centromere protein H (CENP-H) DUF718 PF05336.8 KFM03129.1 - 0.41 10.4 4.0 0.41 10.4 2.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF718) DUF2508 PF10704.4 KFM03129.1 - 0.59 10.3 5.7 0.12 12.5 1.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2508) Flagellar_rod PF05149.7 KFM03129.1 - 0.59 9.2 11.7 0.37 9.9 6.7 1.6 1 1 0 1 1 1 0 Paraflagellar rod protein Ribosomal_L29 PF00831.18 KFM03129.1 - 0.66 9.6 7.0 0.43 10.3 1.4 2.2 2 0 0 2 2 2 0 Ribosomal L29 protein Med9 PF07544.8 KFM03129.1 - 0.68 9.6 9.1 1.1 8.9 0.7 2.7 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Cnl2_NKP2 PF09447.5 KFM03129.1 - 0.7 9.6 5.0 2.2 8.0 0.5 2.3 2 0 0 2 2 2 0 Cnl2/NKP2 family protein Tup_N PF08581.5 KFM03129.1 - 0.83 9.8 11.5 1.3 9.2 3.0 2.6 1 1 1 2 2 2 0 Tup N-terminal DUF4140 PF13600.1 KFM03129.1 - 0.93 9.9 6.7 2.9 8.3 1.3 2.5 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) TMF_TATA_bd PF12325.3 KFM03129.1 - 0.99 9.1 10.0 3.6 7.3 6.1 2.2 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 KFM03129.1 - 1 9.2 12.0 0.41 10.4 5.5 2.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4200 PF13863.1 KFM03129.1 - 1.2 9.1 12.5 2.4 8.1 0.9 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) FlxA PF14282.1 KFM03129.1 - 1.4 8.9 18.1 1.4 8.8 10.9 2.2 1 1 0 1 1 1 0 FlxA-like protein Seryl_tRNA_N PF02403.17 KFM03129.1 - 1.4 8.9 9.2 0.85 9.6 4.3 2.0 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Syntaxin PF00804.20 KFM03129.1 - 1.5 9.0 8.8 0.6 10.2 4.5 1.5 2 0 0 2 2 1 0 Syntaxin MerR-DNA-bind PF09278.6 KFM03129.1 - 1.5 9.2 5.3 2.6 8.5 0.3 2.8 2 1 1 3 3 3 0 MerR, DNA binding Syntaxin-6_N PF09177.6 KFM03129.1 - 1.7 9.1 7.9 5.6 7.4 3.6 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Tnp_P_element PF12017.3 KFM03129.1 - 1.7 7.8 6.6 1.9 7.6 0.8 2.2 1 1 1 2 2 2 0 Transposase protein HR1 PF02185.11 KFM03129.1 - 2.3 8.0 9.9 1.1 9.1 2.3 2.4 2 1 0 2 2 2 0 Hr1 repeat bZIP_1 PF00170.16 KFM03129.1 - 2.8 7.9 6.8 7.9 6.5 0.1 2.7 3 0 0 3 3 3 0 bZIP transcription factor CCDC-167 PF15188.1 KFM03129.1 - 3 7.8 7.0 2.5 8.1 3.2 2.0 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 ACCA PF03255.9 KFM03129.1 - 5 6.6 6.4 63 3.1 4.5 2.3 1 1 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF2443 PF10398.4 KFM03129.1 - 5.5 6.8 6.3 3.5 7.5 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2443) CENP-Q PF13094.1 KFM03129.1 - 6.4 6.7 10.6 16 5.5 7.4 1.7 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Prefoldin PF02996.12 KFM03129.1 - 6.6 6.4 10.8 3 7.5 0.7 2.6 2 1 0 3 3 3 0 Prefoldin subunit BLOC1_2 PF10046.4 KFM03129.1 - 7.2 6.8 11.4 16 5.7 5.3 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF972 PF06156.8 KFM03129.1 - 8.3 6.8 12.0 9.9e+02 0.1 8.3 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Bromodomain PF00439.20 KFM03130.1 - 4.2e-23 81.0 0.4 2.9e-22 78.3 0.2 2.4 2 0 0 2 2 2 1 Bromodomain zf-B_box PF00643.19 KFM03130.1 - 7.7e-12 44.9 20.5 7.6e-09 35.3 5.1 5.0 5 0 0 5 5 5 2 B-box zinc finger PHD PF00628.24 KFM03130.1 - 1.8e-08 33.9 9.6 1.8e-08 33.9 6.7 4.5 4 0 0 4 4 4 1 PHD-finger SpoIISB_antitox PF14185.1 KFM03130.1 - 0.044 13.5 1.6 0.12 12.1 0.7 2.1 2 0 0 2 2 2 0 Antitoxin SpoIISB, type II toxin-antitoxin system C2 PF00168.25 KFM03131.1 - 1.5e-56 188.1 0.0 5.4e-27 93.4 0.0 3.2 3 0 0 3 3 3 2 C2 domain CEP76-C2 PF15627.1 KFM03131.1 - 0.00016 21.2 0.1 0.021 14.3 0.1 2.9 3 0 0 3 3 3 1 CEP76 C2 domain DOCK-C2 PF14429.1 KFM03131.1 - 0.08 12.5 0.1 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 C2 domain in Dock180 and Zizimin proteins Pkinase PF00069.20 KFM03132.1 - 4.9e-53 179.9 0.0 7.7e-53 179.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM03132.1 - 2.8e-24 85.5 0.0 4.6e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFM03132.1 - 3.8e-05 22.8 0.0 6.9e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFM03132.1 - 0.0047 16.6 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KFM03132.1 - 0.011 14.6 0.1 0.017 13.9 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.4 KFM03132.1 - 0.15 11.4 0.0 0.31 10.3 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DRMBL PF07522.9 KFM03133.1 - 2e-16 59.9 0.0 4.1e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 KFM03133.1 - 0.00015 21.3 0.0 0.0012 18.4 0.0 2.1 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Miro PF08477.8 KFM03133.1 - 0.044 14.2 0.0 0.097 13.1 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Adaptin_N PF01602.15 KFM03134.1 - 9.8e-62 208.9 0.0 1.2e-61 208.6 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region B2-adapt-app_C PF09066.5 KFM03134.1 - 1.3e-21 76.5 0.0 2.8e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.1 KFM03134.1 - 1.7e-10 41.0 1.3 6.3e-05 23.1 0.1 4.7 2 2 3 5 5 5 3 HEAT repeats HEAT PF02985.17 KFM03134.1 - 3.2e-09 36.1 4.3 0.28 11.3 0.0 6.1 5 1 1 6 6 6 3 HEAT repeat Cnd1 PF12717.2 KFM03134.1 - 2.7e-08 33.8 0.0 1.1e-07 31.9 0.0 2.0 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 KFM03134.1 - 0.00072 19.9 3.0 4.3 7.9 0.0 5.3 5 1 1 6 6 6 1 HEAT-like repeat Pox_P4B PF03292.9 KFM03134.1 - 0.16 9.8 0.0 1 7.2 0.0 1.9 2 0 0 2 2 2 0 Poxvirus P4B major core protein Y_phosphatase PF00102.22 KFM03136.1 - 3.9e-80 268.5 0.0 4.8e-80 268.2 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KFM03136.1 - 0.0011 19.2 0.0 0.003 17.8 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 KFM03136.1 - 0.0064 16.0 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 KFM03136.1 - 0.16 11.9 0.5 0.65 10.0 0.0 2.2 3 0 0 3 3 3 0 Inositol hexakisphosphate Phtf-FEM1B_bdg PF12129.3 KFM03138.1 - 3.3e-63 211.8 1.3 8.2e-63 210.5 0.9 1.7 1 0 0 1 1 1 1 Male germ-cell putative homeodomain transcription factor PDZ PF00595.19 KFM03139.1 - 1e-63 211.4 8.5 9.6e-16 57.7 0.4 5.5 5 0 0 5 5 5 5 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM03139.1 - 4.5e-26 90.5 0.0 0.00021 21.1 0.0 5.4 5 0 0 5 5 5 5 PDZ domain WW PF00397.21 KFM03139.1 - 2.7e-16 59.1 4.7 3.1e-09 36.5 0.1 2.5 2 0 0 2 2 2 2 WW domain Guanylate_kin PF00625.16 KFM03139.1 - 5.5e-11 42.2 0.0 1.8e-10 40.5 0.0 1.8 2 0 0 2 2 2 1 Guanylate kinase Tricorn_PDZ PF14685.1 KFM03139.1 - 1.6e-05 24.5 4.9 0.53 10.1 0.1 4.8 5 0 0 5 5 5 2 Tricorn protease PDZ domain OB_RNB PF08206.6 KFM03139.1 - 0.071 12.6 1.2 46 3.6 0.0 4.1 4 0 0 4 4 4 0 Ribonuclease B OB domain LRR_8 PF13855.1 KFM03140.1 - 9.4e-60 198.2 35.6 3.9e-15 55.3 3.1 6.6 4 1 2 6 6 6 5 Leucine rich repeat I-set PF07679.11 KFM03140.1 - 4.5e-49 164.2 0.0 9.4e-21 73.4 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM03140.1 - 1.3e-36 124.5 0.0 1.6e-11 44.1 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain LRR_4 PF12799.2 KFM03140.1 - 2.5e-34 116.3 36.2 5.6e-07 29.0 0.2 8.0 4 1 4 9 9 9 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFM03140.1 - 1.1e-26 93.0 0.1 5.9e-11 42.1 0.0 3.3 1 1 2 3 3 3 3 Leucine rich repeats (6 copies) LRR_1 PF00560.28 KFM03140.1 - 2.6e-24 81.4 28.1 0.016 15.1 0.4 13.7 14 0 0 14 14 14 7 Leucine Rich Repeat Ig_3 PF13927.1 KFM03140.1 - 4.5e-22 78.3 0.0 1.6e-07 31.7 0.1 4.2 3 1 0 3 3 3 3 Immunoglobulin domain ig PF00047.20 KFM03140.1 - 1.6e-19 69.7 0.0 8.5e-06 25.7 0.0 3.8 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 KFM03140.1 - 1.1e-14 54.2 0.1 2.7e-05 24.0 0.3 4.3 3 2 0 3 3 3 3 Immunoglobulin V-set domain LRR_6 PF13516.1 KFM03140.1 - 1.9e-11 42.8 36.8 0.18 11.9 0.1 11.3 9 2 2 11 11 11 5 Leucine Rich repeat C2-set_2 PF08205.7 KFM03140.1 - 4e-11 42.6 0.1 0.0024 17.7 0.0 3.6 3 0 0 3 3 3 3 CD80-like C2-set immunoglobulin domain LRR_7 PF13504.1 KFM03140.1 - 1e-08 33.9 32.4 0.23 11.8 0.2 11.7 13 0 0 13 13 10 3 Leucine rich repeat LRR_9 PF14580.1 KFM03140.1 - 1.2e-05 24.9 10.4 0.28 10.7 0.8 4.3 1 1 3 4 4 4 3 Leucine-rich repeat LRRCT PF01463.19 KFM03140.1 - 0.0008 19.4 0.0 0.0026 17.8 0.0 2.0 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain C1-set PF07654.10 KFM03140.1 - 0.0062 16.5 0.1 0.3 11.1 0.3 2.9 3 0 0 3 3 3 1 Immunoglobulin C1-set domain Herpes_gE PF02480.11 KFM03140.1 - 0.053 11.7 0.1 0.29 9.3 0.0 2.1 3 0 0 3 3 3 0 Alphaherpesvirus glycoprotein E MFS_1 PF07690.11 KFM03141.1 - 1.4e-37 129.2 37.1 3.3e-31 108.2 18.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFM03141.1 - 0.00099 17.7 9.6 0.00099 17.7 6.6 3.5 3 1 0 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.2 KFM03141.1 - 0.0022 17.7 5.6 0.053 13.3 1.9 3.5 3 1 1 4 4 4 1 MFS_1 like family DUF1077 PF06417.7 KFM03141.1 - 4.2 6.7 5.5 12 5.2 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1077) TAFA PF12020.3 KFM03142.1 - 3.2e-40 136.1 7.5 4.1e-40 135.8 5.2 1.1 1 0 0 1 1 1 1 TAFA family PP2C PF00481.16 KFM03143.1 - 1.9e-29 102.8 0.0 3.2e-13 49.6 0.0 3.1 3 0 0 3 3 3 3 Protein phosphatase 2C SpoIIE PF07228.7 KFM03143.1 - 6.1e-06 26.0 0.0 0.0086 15.7 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Ras PF00071.17 KFM03144.1 - 3.6e-58 195.5 0.0 4.2e-58 195.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM03144.1 - 1.3e-16 61.1 0.0 1.8e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM03144.1 - 2.1e-10 40.1 0.0 3.6e-10 39.3 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFM03144.1 - 3.1e-05 23.4 0.0 8.2e-05 22.1 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFM03144.1 - 0.013 14.6 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KFM03144.1 - 0.035 13.3 0.0 0.058 12.6 0.0 1.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_12 PF13087.1 KFM03145.1 - 2.2e-48 164.3 0.0 4.1e-48 163.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KFM03145.1 - 3.3e-30 105.4 0.0 5.7e-15 55.5 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.1 KFM03145.1 - 7.3e-09 35.2 0.0 1.7e-07 30.8 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KFM03145.1 - 2.4e-08 33.7 0.0 2.5e-05 23.9 0.0 2.6 3 0 0 3 3 3 2 AAA domain ResIII PF04851.10 KFM03145.1 - 6e-05 22.9 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA PF00004.24 KFM03145.1 - 0.0088 16.2 0.0 0.18 12.0 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFM03145.1 - 0.012 15.7 0.0 0.035 14.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain UvrD-helicase PF00580.16 KFM03145.1 - 0.059 12.6 0.0 0.13 11.4 0.0 1.6 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 KFM03145.1 - 0.082 12.3 0.2 21 4.4 0.0 2.8 2 1 1 3 3 3 0 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.1 KFM03145.1 - 0.097 12.8 0.0 0.27 11.3 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_24 PF13479.1 KFM03145.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain HOOK PF05622.7 KFM03145.1 - 0.2 9.4 0.0 0.3 8.8 0.0 1.1 1 0 0 1 1 1 0 HOOK protein PIF1 PF05970.9 KFM03145.1 - 0.21 10.4 0.0 18 4.1 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase F-actin_cap_A PF01267.12 KFM03146.1 - 9e-103 343.0 0.6 1e-102 342.8 0.4 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit ST7 PF04184.7 KFM03147.1 - 1.2e-302 1004.0 2.1 1.3e-302 1003.8 1.4 1.0 1 0 0 1 1 1 1 ST7 protein TPR_6 PF13174.1 KFM03147.1 - 0.00058 20.1 0.5 0.0025 18.1 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFM03147.1 - 0.022 14.6 4.4 1.5 8.9 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFM03147.1 - 0.029 13.9 4.4 8.9 6.1 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Clathrin PF00637.15 KFM03147.1 - 0.032 13.8 0.2 0.067 12.7 0.1 1.5 1 0 0 1 1 1 0 Region in Clathrin and VPS TPR_16 PF13432.1 KFM03147.1 - 0.15 12.7 5.5 0.89 10.3 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFM03147.1 - 0.94 9.8 7.0 0.62 10.4 0.1 3.4 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 KFM03147.1 - 1.1 8.9 9.0 15 5.2 0.1 4.1 3 1 2 5 5 5 0 TPR repeat TPR_14 PF13428.1 KFM03147.1 - 7.2 7.5 10.5 46 5.0 0.1 5.1 5 1 1 6 6 6 0 Tetratricopeptide repeat wnt PF00110.14 KFM03148.1 - 4.6e-124 413.6 29.1 5.2e-124 413.4 20.2 1.0 1 0 0 1 1 1 1 wnt family CortBP2 PF09727.4 KFM03149.1 - 2.7e-58 196.6 17.0 2.7e-58 196.6 11.8 2.2 1 1 1 2 2 2 1 Cortactin-binding protein-2 AAA_13 PF13166.1 KFM03149.1 - 6.3 5.1 28.1 11 4.3 19.5 1.3 1 0 0 1 1 1 0 AAA domain DUF4164 PF13747.1 KFM03149.1 - 7.8 6.7 30.4 2.3 8.4 8.7 3.6 2 2 0 2 2 2 0 Domain of unknown function (DUF4164) BTB_2 PF02214.17 KFM03150.1 - 3.1e-29 101.0 0.1 6.8e-29 99.9 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans PF00520.26 KFM03150.1 - 2.3e-22 79.2 14.3 3.7e-22 78.5 8.7 2.0 2 0 0 2 2 2 1 Ion transport protein Shal-type PF11601.3 KFM03150.1 - 4.3e-16 58.0 13.9 7e-16 57.4 9.6 1.3 1 0 0 1 1 1 1 Shal-type voltage-gated potassium channels PKD_channel PF08016.7 KFM03150.1 - 0.13 10.7 11.5 0.25 9.6 8.0 1.6 1 1 0 1 1 1 0 Polycystin cation channel Ion_trans_2 PF07885.11 KFM03150.1 - 2.7 7.7 15.7 0.045 13.4 3.0 2.7 3 0 0 3 3 3 0 Ion channel DUF3399 PF11879.3 KFM03151.1 - 1.3e-48 163.5 11.7 1.3e-48 163.5 8.1 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3399) Ion_trans_2 PF07885.11 KFM03151.1 - 0.0012 18.4 0.1 0.0019 17.8 0.1 1.3 1 0 0 1 1 1 1 Ion channel DEAD PF00270.24 KFM03152.1 - 4.4e-31 107.6 0.0 9.8e-31 106.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFM03152.1 - 2.1e-21 75.5 0.0 5.4e-21 74.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFM03152.1 - 0.0003 20.6 0.2 0.0011 18.8 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KFM03152.1 - 0.00034 20.3 0.1 0.00069 19.3 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KFM03152.1 - 0.03 14.4 0.0 0.11 12.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KFM03152.1 - 0.048 13.2 0.0 0.09 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain CMS1 PF14617.1 KFM03152.1 - 0.063 12.3 0.0 0.16 11.0 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit FAM212 PF15342.1 KFM03153.1 - 6.9e-28 96.0 0.6 1.6e-27 94.9 0.4 1.6 1 0 0 1 1 1 1 FAM212 family Ras PF00071.17 KFM03154.1 - 7.1e-53 178.3 0.3 7.9e-53 178.1 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM03154.1 - 4.6e-21 75.5 0.1 5.7e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM03154.1 - 3e-09 36.3 0.1 3.3e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFM03154.1 - 1.6e-05 24.4 0.2 3.3e-05 23.3 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFM03154.1 - 6.4e-05 22.8 0.0 8.9e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 KFM03154.1 - 0.00086 18.0 0.0 0.13 10.9 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit AAA_22 PF13401.1 KFM03154.1 - 0.035 14.2 0.3 1 9.4 0.2 2.3 1 1 0 1 1 1 0 AAA domain 7tm_1 PF00001.16 KFM03155.1 - 7.8e-54 182.5 23.3 9.1e-54 182.2 16.2 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM03155.1 - 3.2e-09 36.3 21.7 4.4e-09 35.8 15.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx MraZ PF02381.13 KFM03155.1 - 0.064 13.0 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 MraZ protein 7TM_GPCR_Srx PF10328.4 KFM03155.1 - 1.2 8.1 25.5 0.029 13.4 12.3 2.2 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.16 KFM03156.1 - 4.3e-55 186.6 23.9 5.1e-55 186.3 16.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM03156.1 - 5.3e-12 45.4 23.5 6.4e-12 45.1 16.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Mt_ATP-synt_B PF05405.9 KFM03157.1 - 1.3e-50 171.0 9.3 1.5e-50 170.8 6.5 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) WD40 PF00400.27 KFM03158.1 - 6.5e-11 41.6 20.1 7.9e-06 25.5 0.5 5.4 6 0 0 6 6 6 4 WD domain, G-beta repeat EF-hand_7 PF13499.1 KFM03161.1 - 2.2e-23 82.1 5.2 9.8e-13 48.0 0.2 3.5 2 1 1 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.27 KFM03161.1 - 4.8e-22 75.5 12.3 4.8e-07 28.6 0.3 4.8 4 1 1 5 5 5 3 EF hand EF-hand_6 PF13405.1 KFM03161.1 - 1.6e-19 67.9 5.2 5.9e-05 22.6 0.0 4.7 4 1 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.1 KFM03161.1 - 2.8e-18 65.2 5.9 4.9e-09 35.6 0.4 2.7 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 KFM03161.1 - 1.4e-15 55.7 8.0 2.2e-05 23.6 0.5 4.6 4 1 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.4 KFM03161.1 - 9e-08 32.1 0.5 6.5e-05 22.9 0.0 2.9 1 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFM03161.1 - 5.5e-06 26.0 2.9 0.089 12.5 0.0 3.1 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 KFM03161.1 - 0.058 13.0 2.2 1.3 8.7 0.3 2.6 2 0 0 2 2 2 0 EF hand DUF2004 PF09406.5 KFM03161.1 - 0.12 12.4 0.8 0.92 9.6 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2004) VCBS PF13517.1 KFM03161.1 - 0.3 11.4 2.8 14 6.0 0.1 3.1 2 1 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella EF-hand_1 PF00036.27 KFM03162.1 - 6.9e-24 81.2 9.1 1.4e-06 27.1 0.1 4.6 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.1 KFM03162.1 - 6.5e-22 77.4 1.5 9.5e-14 51.2 0.0 3.0 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KFM03162.1 - 7.9e-19 65.8 7.3 9.1e-05 22.0 0.4 4.9 4 2 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 KFM03162.1 - 4.7e-17 61.3 1.1 1.3e-08 34.3 0.0 3.6 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 KFM03162.1 - 5.4e-17 60.2 7.7 1.6e-05 24.0 0.1 4.6 5 0 0 5 5 5 3 EF hand SPARC_Ca_bdg PF10591.4 KFM03162.1 - 4.5e-07 29.8 0.4 0.16 12.0 0.0 3.2 1 1 2 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFM03162.1 - 0.01 15.5 2.1 2.2 8.0 0.1 2.9 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand DUF3408 PF11888.3 KFM03162.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) IRF-3 PF10401.4 KFM03163.1 - 1.7e-65 219.9 0.1 2.5e-65 219.4 0.1 1.3 1 0 0 1 1 1 1 Interferon-regulatory factor 3 IRF PF00605.12 KFM03163.1 - 1.5e-48 163.1 0.3 3.2e-48 162.0 0.2 1.5 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor adh_short PF00106.20 KFM03164.1 - 3.3e-26 92.1 0.0 4.3e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFM03164.1 - 1.1e-09 38.4 0.1 1.5e-09 37.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFM03164.1 - 6e-09 35.8 1.4 7.8e-08 32.1 1.0 2.0 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.5 KFM03164.1 - 1.1e-05 24.7 0.0 1.6e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Shikimate_DH PF01488.15 KFM03164.1 - 0.0091 16.1 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.3 KFM03164.1 - 0.02 14.6 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 KFM03164.1 - 0.027 13.5 0.0 0.048 12.7 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 KFM03164.1 - 0.099 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding adh_short PF00106.20 KFM03165.1 - 8e-26 90.9 0.1 1e-25 90.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFM03165.1 - 2e-09 37.5 0.1 2.7e-09 37.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFM03165.1 - 7.4e-08 32.2 0.8 0.0013 18.4 0.1 2.1 2 0 0 2 2 2 2 KR domain Shikimate_DH PF01488.15 KFM03165.1 - 0.00034 20.7 0.1 0.00053 20.0 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF1776 PF08643.5 KFM03165.1 - 0.00036 19.7 0.0 0.00053 19.2 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 KFM03165.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 KFM03165.1 - 0.023 13.8 0.0 0.043 12.8 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FMO-like PF00743.14 KFM03165.1 - 0.033 12.3 0.0 0.054 11.7 0.0 1.3 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like NAD_binding_2 PF03446.10 KFM03165.1 - 0.056 13.2 0.0 0.088 12.6 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.1 KFM03165.1 - 0.12 12.3 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding G0-G1_switch_2 PF15103.1 KFM03166.1 - 2.6e-40 136.7 0.8 2.9e-40 136.5 0.6 1.0 1 0 0 1 1 1 1 G0/G1 switch protein 2 HILPDA PF15220.1 KFM03166.1 - 0.14 12.1 0.1 0.21 11.5 0.1 1.3 1 0 0 1 1 1 0 Hypoxia-inducible lipid droplet-associated Laminin_EGF PF00053.19 KFM03167.1 - 2.4e-48 161.8 132.9 3.7e-11 42.7 6.6 7.4 7 1 0 7 7 6 6 Laminin EGF-like (Domains III and V) Laminin_N PF00055.12 KFM03167.1 - 1.9e-42 144.9 0.0 6.3e-42 143.1 0.0 2.0 1 0 0 1 1 1 1 Laminin N-terminal (Domain VI) DUF948 PF06103.6 KFM03167.1 - 0.0098 15.7 7.6 0.35 10.7 0.1 4.6 4 1 0 4 4 4 1 Bacterial protein of unknown function (DUF948) Erp_C PF06780.6 KFM03167.1 - 0.066 13.0 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 Erp protein C-terminus Syntaxin PF00804.20 KFM03167.1 - 0.079 13.1 24.7 0.16 12.1 1.1 4.7 4 0 0 4 4 4 0 Syntaxin NPV_P10 PF05531.7 KFM03167.1 - 0.088 13.0 8.1 2.1 8.6 0.0 5.1 3 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein F5_F8_type_C PF00754.20 KFM03167.1 - 0.1 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 F5/8 type C domain BNR PF02012.15 KFM03167.1 - 0.13 12.1 0.1 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 BNR/Asp-box repeat Cauli_AT PF03233.8 KFM03167.1 - 0.31 10.7 2.6 2.8 7.6 0.0 3.1 3 0 0 3 3 3 0 Aphid transmission protein Streptin-Immun PF11083.3 KFM03167.1 - 0.72 9.8 4.0 1.4 8.9 0.1 3.3 4 0 0 4 4 4 0 Lantibiotic streptin immunity protein Laminin_II PF06009.7 KFM03167.1 - 0.9 9.3 26.5 2 8.1 1.0 5.1 2 1 4 6 6 6 0 Laminin Domain II Laminin_I PF06008.9 KFM03167.1 - 4.6 6.4 33.4 1.1 8.4 7.8 4.3 2 2 0 3 3 3 0 Laminin Domain I MCPsignal PF00015.16 KFM03167.1 - 6.3 6.2 24.0 0.23 10.9 3.4 3.4 2 2 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain COG2 PF06148.6 KFM03167.1 - 9.5 6.1 14.9 4 7.3 0.9 4.3 3 2 2 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 Pkinase PF00069.20 KFM03168.1 - 2.5e-75 252.9 0.0 3.1e-75 252.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM03168.1 - 1.4e-33 116.1 0.0 1.7e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM03168.1 - 2.4e-08 33.3 0.0 3.5e-08 32.7 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFM03168.1 - 0.00019 20.5 0.0 0.0003 19.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFM03168.1 - 0.0004 19.7 0.1 0.00072 18.9 0.1 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KFM03168.1 - 0.0034 17.1 0.0 0.094 12.4 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KFM03168.1 - 0.0042 16.4 0.1 0.009 15.3 0.0 1.6 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Plexin_cytopl PF08337.7 KFM03169.1 - 2.6e-265 880.8 1.1 3.2e-265 880.5 0.7 1.1 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain Sema PF01403.14 KFM03169.1 - 8.1e-85 284.9 0.0 1.2e-84 284.3 0.0 1.3 1 0 0 1 1 1 1 Sema domain TIG PF01833.19 KFM03169.1 - 6.5e-35 118.9 13.1 1.9e-10 40.5 0.0 6.3 6 0 0 6 6 6 4 IPT/TIG domain PSI PF01437.20 KFM03169.1 - 2.5e-22 78.7 56.7 8.3e-11 41.8 9.2 3.6 3 0 0 3 3 3 3 Plexin repeat RasGAP PF00616.14 KFM03169.1 - 1.3e-05 24.9 0.2 0.005 16.5 0.2 2.3 2 0 0 2 2 2 2 GTPase-activator protein for Ras-like GTPase IncA PF04156.9 KFM03169.1 - 0.0019 17.8 0.6 0.0019 17.8 0.4 1.6 2 0 0 2 2 2 1 IncA protein EphA2_TM PF14575.1 KFM03169.1 - 0.076 13.4 0.1 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF948 PF06103.6 KFM03169.1 - 0.23 11.3 0.4 0.6 9.9 0.3 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) CD34_antigen PF06365.7 KFM03170.1 - 6.4e-20 71.6 0.0 6.8e-20 71.5 0.0 1.0 1 0 0 1 1 1 1 CD34/Podocalyxin family DUF4064 PF13273.1 KFM03170.1 - 0.1 12.7 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Sushi PF00084.15 KFM03172.1 - 3.3e-50 168.2 29.2 2.8e-11 43.6 1.9 6.4 5 2 1 6 6 6 6 Sushi domain (SCR repeat) DUF1035 PF06281.7 KFM03172.1 - 0.035 13.8 0.4 4.5 7.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1035) TM_helix PF05552.7 KFM03172.1 - 0.18 11.5 1.8 0.29 10.8 1.2 1.3 1 0 0 1 1 1 0 Conserved TM helix DUF281 PF03436.8 KFM03172.1 - 0.33 11.0 8.3 2.5 8.2 0.0 4.0 3 1 0 3 3 3 0 Domain of unknown function (DUF281) Sushi PF00084.15 KFM03173.1 - 3.6e-16 59.2 2.3 1.8e-11 44.1 0.2 2.1 2 0 0 2 2 2 2 Sushi domain (SCR repeat) Sushi PF00084.15 KFM03174.1 - 5e-35 119.6 11.3 1.5e-12 47.6 0.9 3.0 3 0 0 3 3 3 3 Sushi domain (SCR repeat) HRM PF02793.17 KFM03174.1 - 0.00014 21.7 7.8 0.015 15.2 0.5 3.2 2 1 1 3 3 3 2 Hormone receptor domain cEGF PF12662.2 KFM03174.1 - 0.52 10.0 6.4 11 5.7 0.1 3.5 3 0 0 3 3 3 0 Complement Clr-like EGF-like Sushi PF00084.15 KFM03175.1 - 1e-36 125.0 13.5 4.4e-13 49.3 0.5 3.0 3 0 0 3 3 3 3 Sushi domain (SCR repeat) HRM PF02793.17 KFM03175.1 - 1e-05 25.4 6.2 0.0052 16.7 0.0 3.3 2 1 1 3 3 3 2 Hormone receptor domain CBM_14 PF01607.19 KFM03175.1 - 0.0092 15.8 4.3 2.2 8.2 0.3 2.9 3 0 0 3 3 3 2 Chitin binding Peritrophin-A domain DUF3601 PF12208.3 KFM03175.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3601) cEGF PF12662.2 KFM03175.1 - 0.54 9.9 5.4 42 3.8 0.0 3.8 3 1 0 3 3 3 0 Complement Clr-like EGF-like Sushi PF00084.15 KFM03176.1 - 3.3e-71 235.5 35.8 3e-11 43.4 0.7 7.1 7 0 0 7 7 7 7 Sushi domain (SCR repeat) cEGF PF12662.2 KFM03176.1 - 1.4e-05 24.5 19.2 1.2 8.8 0.1 7.1 7 0 0 7 7 7 5 Complement Clr-like EGF-like DUF1737 PF08410.5 KFM03176.1 - 0.0011 18.6 0.0 5.8 6.7 0.0 4.1 5 0 0 5 5 5 2 Domain of unknown function (DUF1737) Sushi PF00084.15 KFM03177.1 - 3.5e-25 88.1 8.9 6.7e-11 42.3 0.5 3.0 3 0 0 3 3 3 3 Sushi domain (SCR repeat) Sushi PF00084.15 KFM03178.1 - 8e-21 74.1 3.3 1.5e-09 38.0 0.1 3.0 3 0 0 3 3 3 3 Sushi domain (SCR repeat) Sushi PF00084.15 KFM03179.1 - 3.3e-63 209.8 37.6 1e-12 48.1 0.5 6.2 6 0 0 6 6 6 6 Sushi domain (SCR repeat) cEGF PF12662.2 KFM03179.1 - 0.25 11.0 6.5 14 5.4 0.1 4.5 4 0 0 4 4 4 0 Complement Clr-like EGF-like Sushi PF00084.15 KFM03180.1 - 4.3e-93 305.5 59.0 9.8e-13 48.2 0.3 10.3 9 1 1 10 10 10 10 Sushi domain (SCR repeat) cEGF PF12662.2 KFM03180.1 - 1.7 8.3 15.3 7.6 6.2 0.1 6.5 6 0 0 6 6 6 0 Complement Clr-like EGF-like 6PF2K PF01591.13 KFM03181.1 - 2.2e-101 337.5 1.3 3e-101 337.1 0.9 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KFM03181.1 - 9.4e-36 123.2 0.0 1.5e-35 122.6 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KFM03181.1 - 1.2e-09 38.1 0.0 2.3e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KFM03181.1 - 6.5e-06 25.5 0.1 1.3e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 KFM03181.1 - 2.5e-05 25.0 0.4 7.6e-05 23.5 0.1 2.0 2 1 0 2 2 2 1 AAA domain DUF421 PF04239.7 KFM03181.1 - 0.034 13.6 0.0 0.088 12.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF421) Zeta_toxin PF06414.7 KFM03181.1 - 0.037 13.1 0.0 0.063 12.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin APS_kinase PF01583.15 KFM03181.1 - 0.05 13.2 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.1 KFM03181.1 - 0.074 13.3 0.1 1.6 9.0 0.0 2.5 2 1 0 2 2 2 0 AAA domain His_Phos_2 PF00328.17 KFM03181.1 - 0.09 12.0 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) OTU PF02338.14 KFM03182.1 - 3.1e-11 43.9 0.0 5.6e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease zf-C2H2_2 PF12756.2 KFM03182.1 - 0.038 14.1 0.0 0.077 13.1 0.0 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) E6 PF00518.12 KFM03182.1 - 0.1 12.9 0.5 0.56 10.5 0.0 2.1 2 0 0 2 2 2 0 Early Protein (E6) zf-met PF12874.2 KFM03182.1 - 0.39 10.9 2.1 2.5 8.4 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type SARG PF15385.1 KFM03183.1 - 4.6e-118 395.7 33.6 1e-82 279.1 17.6 2.0 1 1 1 2 2 2 2 Specifically androgen-regulated gene protein IL10 PF00726.12 KFM03184.1 - 3.6e-07 29.6 0.1 3.9e-07 29.5 0.1 1.1 1 0 0 1 1 1 1 Interleukin 10 IL22 PF14565.1 KFM03184.1 - 1.6e-05 25.0 0.3 2.2e-05 24.5 0.2 1.2 1 0 0 1 1 1 1 Interleukin 22 IL-10-related T-cell-derived-inducible factor IL10 PF00726.12 KFM03185.1 - 8.1e-50 168.4 1.0 9.7e-50 168.1 0.7 1.0 1 0 0 1 1 1 1 Interleukin 10 IL22 PF14565.1 KFM03185.1 - 4.8e-09 36.4 0.3 6.5e-09 35.9 0.2 1.1 1 0 0 1 1 1 1 Interleukin 22 IL-10-related T-cell-derived-inducible factor Translin PF01997.11 KFM03185.1 - 0.22 11.0 2.3 0.33 10.5 0.5 2.0 2 1 0 2 2 2 0 Translin family Pkinase PF00069.20 KFM03186.1 - 1e-58 198.5 0.0 1.4e-58 198.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM03186.1 - 6e-27 94.3 0.0 8.7e-27 93.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM03186.1 - 2.6e-06 26.6 0.0 3.6e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFM03186.1 - 1.4e-05 24.2 0.0 2.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KFM03186.1 - 0.035 13.6 0.4 0.095 12.2 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pkinase PF00069.20 KFM03187.1 - 1.2e-60 204.8 0.2 6.1e-60 202.5 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM03187.1 - 1.4e-21 76.7 0.1 2.8e-21 75.7 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFM03187.1 - 4.3e-05 23.3 0.0 0.0027 17.4 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KFM03187.1 - 0.00034 19.9 2.5 0.021 14.1 0.0 2.5 3 0 0 3 3 3 2 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 KFM03187.1 - 0.00084 18.9 0.2 0.0021 17.6 0.1 1.6 1 1 1 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.17 KFM03187.1 - 0.0045 16.3 2.1 0.0051 16.1 0.2 1.9 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 KFM03187.1 - 0.035 13.1 0.2 0.063 12.3 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SUI1 PF01253.17 KFM03188.1 - 3.7e-15 55.4 0.3 6.7e-15 54.6 0.2 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 PUA PF01472.15 KFM03188.1 - 1.6e-05 24.5 0.2 7.3e-05 22.4 0.1 2.1 2 0 0 2 2 2 1 PUA domain SWIB PF02201.13 KFM03188.1 - 0.008 15.8 0.1 0.022 14.4 0.1 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain RA PF00788.18 KFM03189.1 - 3.6e-17 62.6 0.1 1e-16 61.1 0.0 1.9 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain YusW PF14039.1 KFM03189.1 - 0.18 12.0 1.6 0.59 10.4 0.1 2.3 2 0 0 2 2 2 0 YusW-like protein 4HB_MCP_1 PF12729.2 KFM03189.1 - 1.5 8.1 4.8 1.4 8.2 1.0 2.1 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction Pkinase PF00069.20 KFM03190.1 - 5.1e-48 163.4 0.0 1.3e-47 162.1 0.0 1.6 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM03190.1 - 2.8e-29 101.9 0.0 4.5e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM03190.1 - 0.00016 20.7 0.0 0.0013 17.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KFM03190.1 - 0.024 14.3 0.0 1.9 8.1 0.0 2.5 1 1 0 2 2 2 0 Phosphotransferase enzyme family RhoGAP PF00620.22 KFM03191.1 - 5.6e-48 162.4 1.1 4.4e-47 159.4 0.0 2.9 2 1 1 3 3 3 1 RhoGAP domain FCH PF00611.18 KFM03191.1 - 2.9e-19 69.0 3.3 2.9e-19 69.0 2.3 2.8 4 0 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 KFM03191.1 - 4.4e-10 38.9 0.0 7.9e-10 38.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM03191.1 - 6.9e-10 38.1 0.0 1.3e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFM03191.1 - 5.9e-09 35.2 0.0 1.3e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain FlaC_arch PF05377.6 KFM03191.1 - 0.0049 16.7 6.7 0.021 14.7 1.8 3.2 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) KIP1 PF07765.7 KFM03191.1 - 0.3 10.9 4.4 4 7.3 0.3 3.3 3 0 0 3 3 3 0 KIP1-like protein DUF4164 PF13747.1 KFM03191.1 - 8.9 6.5 11.8 2.2 8.4 2.7 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) FAM72 PF14976.1 KFM03192.1 - 1.2e-53 180.9 1.7 1.3e-53 180.8 1.2 1.0 1 0 0 1 1 1 1 FAM72 protein 7tm_1 PF00001.16 KFM03193.1 - 1.1e-55 188.5 8.7 1.3e-55 188.2 6.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM03193.1 - 4.3e-10 39.1 4.9 6.2e-10 38.6 3.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 KFM03193.1 - 2.4e-06 26.8 0.2 5.2e-06 25.8 0.1 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Srg PF02118.16 KFM03193.1 - 0.0023 17.4 4.4 0.0023 17.4 3.0 2.1 2 1 0 2 2 2 1 Srg family chemoreceptor Asp PF00026.18 KFM03194.1 - 5.3e-124 413.5 0.5 6.1e-124 413.3 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KFM03194.1 - 7.7e-09 35.7 0.3 1.9e-08 34.4 0.2 1.6 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal A1_Propeptide PF07966.7 KFM03194.1 - 4.2e-05 23.1 0.6 6.7e-05 22.5 0.4 1.3 1 0 0 1 1 1 1 A1 Propeptide Asp_protease_2 PF13650.1 KFM03194.1 - 0.00014 22.3 0.1 0.5 10.8 0.0 2.8 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KFM03194.1 - 0.0076 15.8 0.0 0.12 11.8 0.0 2.4 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Ras PF00071.17 KFM03195.1 - 3.4e-32 111.0 0.0 3.8e-32 110.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM03195.1 - 5.7e-10 39.7 0.0 9e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM03195.1 - 5.1e-09 35.6 0.0 5.7e-09 35.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFM03195.1 - 0.00032 20.2 0.0 0.00058 19.3 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Sulfate_transp PF00916.15 KFM03196.1 - 6.9e-55 186.0 13.0 6.9e-55 186.0 9.0 2.4 3 0 0 3 3 3 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KFM03196.1 - 2.2e-26 91.3 2.5 2.2e-26 91.3 1.7 2.6 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KFM03196.1 - 1.3e-25 89.0 0.0 2.2e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 STAS domain Peptidase_M20 PF01546.23 KFM03197.1 - 2.5e-28 98.8 0.0 3.6e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KFM03197.1 - 2e-16 59.7 0.0 4.2e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain MgtE PF01769.11 KFM03198.1 - 8.6e-46 155.5 19.8 4.9e-29 101.3 4.9 2.8 2 1 1 3 3 3 2 Divalent cation transporter Ras PF00071.17 KFM03199.1 - 1.6e-29 102.3 0.0 1.8e-29 102.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Arf PF00025.16 KFM03199.1 - 2.3e-09 36.7 0.1 3.2e-09 36.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 KFM03199.1 - 7.7e-08 32.8 0.0 1.3e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein DUF2276 PF10040.4 KFM03199.1 - 0.023 14.9 0.0 0.039 14.1 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2276) Gtr1_RagA PF04670.7 KFM03199.1 - 0.057 12.5 0.1 0.091 11.8 0.1 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region FAM74 PF15026.1 KFM03200.1 - 2.9 7.5 10.7 0.26 10.9 3.4 2.1 2 0 0 2 2 2 0 FAM74 protein MFS_1 PF07690.11 KFM03201.1 - 3.7e-13 48.9 34.1 2e-12 46.5 18.1 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFM03201.1 - 4.3e-11 41.8 1.2 4.3e-11 41.8 0.8 3.2 4 0 0 4 4 4 2 MFS/sugar transport protein Ets PF00178.17 KFM03202.1 - 6.1e-38 128.8 2.0 9e-38 128.2 1.4 1.3 1 0 0 1 1 1 1 Ets-domain HSF_DNA-bind PF00447.12 KFM03202.1 - 0.069 13.3 0.2 0.15 12.2 0.2 1.5 1 0 0 1 1 1 0 HSF-type DNA-binding MFS_1 PF07690.11 KFM03203.1 - 3.9e-09 35.6 40.7 3.9e-06 25.8 15.9 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 KFM03204.1 - 1.4e-70 237.3 0.0 1.7e-70 237.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM03204.1 - 2.2e-33 115.4 0.0 2.9e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM03204.1 - 6.5e-06 25.3 0.0 9.3e-06 24.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFM03204.1 - 0.00083 18.4 0.1 0.0015 17.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KFM03204.1 - 0.052 12.8 0.0 0.078 12.3 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.6 KFM03204.1 - 0.053 12.3 0.1 0.1 11.4 0.0 1.4 1 1 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 KFM03204.1 - 0.081 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kelch_1 PF01344.20 KFM03205.1 - 1.2e-50 168.8 0.0 2e-09 36.8 0.0 7.1 7 0 0 7 7 7 7 Kelch motif Kelch_6 PF13964.1 KFM03205.1 - 2.5e-41 138.2 0.6 1.4e-08 34.5 0.0 7.1 2 2 5 7 7 7 7 Kelch motif Kelch_4 PF13418.1 KFM03205.1 - 1.2e-25 88.9 0.4 3e-06 26.8 0.0 6.4 6 1 1 7 7 7 5 Galactose oxidase, central domain Kelch_3 PF13415.1 KFM03205.1 - 2.2e-23 81.7 0.0 3.6e-06 26.9 0.0 6.1 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.10 KFM03205.1 - 6.9e-23 79.4 0.0 3.7e-06 26.4 0.0 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.1 KFM03205.1 - 1.3e-10 40.9 0.2 0.012 15.5 0.0 5.5 6 0 0 6 6 6 3 Kelch motif Tmemb_cc2 PF10267.4 KFM03206.1 - 3.3e-191 635.0 8.7 5.1e-191 634.4 6.0 1.3 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein ABC2_membrane_3 PF12698.2 KFM03206.1 - 0.0075 15.3 1.1 0.015 14.3 0.1 1.8 2 0 0 2 2 2 1 ABC-2 family transporter protein DUF1479 PF07350.7 KFM03206.1 - 0.014 13.9 4.4 0.035 12.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1479) DUF2313 PF10076.4 KFM03206.1 - 0.018 14.4 1.1 0.03 13.7 0.2 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2313) OmpH PF03938.9 KFM03206.1 - 0.43 10.4 24.2 1.6 8.6 8.6 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Lipoprotein_20 PF13942.1 KFM03206.1 - 0.69 9.4 17.4 1.2 8.6 1.4 2.5 2 1 0 2 2 2 0 YfhG lipoprotein Baculo_PEP_C PF04513.7 KFM03206.1 - 1.2 8.8 14.5 0.047 13.5 1.1 3.7 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF342 PF03961.8 KFM03206.1 - 1.8 6.9 19.7 0.51 8.7 3.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Prominin PF05478.6 KFM03206.1 - 2.5 5.5 20.0 0.12 9.8 7.0 2.6 2 1 0 2 2 2 0 Prominin DUF2207 PF09972.4 KFM03206.1 - 6.3 5.2 8.7 0.37 9.3 0.2 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) CorA PF01544.13 KFM03206.1 - 6.4 5.7 16.1 3.5 6.5 3.4 2.6 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Pkinase PF00069.20 KFM03207.1 - 4.3e-43 147.3 0.0 1.4e-42 145.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM03207.1 - 1e-35 123.0 0.0 1.8e-35 122.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM03207.1 - 0.0001 21.4 0.3 0.00023 20.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFM03207.1 - 0.0023 17.0 0.5 0.0054 15.8 0.1 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFM03207.1 - 0.026 14.2 1.9 0.29 10.8 0.0 2.7 3 0 0 3 3 3 0 Phosphotransferase enzyme family WD40 PF00400.27 KFM03208.1 - 3.1e-15 55.3 23.2 3.8e-07 29.7 1.8 6.8 7 1 0 7 7 7 5 WD domain, G-beta repeat DUF3312 PF11768.3 KFM03208.1 - 0.091 10.9 0.1 0.14 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Ig_2 PF13895.1 KFM03209.1 - 0.00049 20.1 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFM03209.1 - 0.0072 16.4 1.3 0.0098 15.9 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.12 KFM03209.1 - 0.049 13.5 0.0 0.26 11.1 0.0 2.2 1 1 0 1 1 1 0 Immunoglobulin V-set domain TSP_1 PF00090.14 KFM03209.1 - 0.17 12.0 4.4 0.37 10.9 3.0 1.5 1 0 0 1 1 1 0 Thrombospondin type 1 domain Ig_3 PF13927.1 KFM03209.1 - 0.35 11.3 0.1 0.35 11.3 0.1 2.3 3 1 0 3 3 3 0 Immunoglobulin domain I-set PF07679.11 KFM03210.1 - 2.7e-70 232.2 0.0 5.5e-16 58.1 0.0 6.8 7 0 0 7 7 7 6 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM03210.1 - 4.9e-60 199.6 0.0 5.7e-11 42.3 0.0 6.6 5 1 1 6 6 6 6 Immunoglobulin domain Ig_3 PF13927.1 KFM03210.1 - 9.8e-52 173.3 0.0 7.3e-08 32.7 0.0 7.8 7 1 1 8 8 8 6 Immunoglobulin domain fn3 PF00041.16 KFM03210.1 - 1.3e-47 159.8 2.0 3.5e-17 62.3 0.0 4.6 4 0 0 4 4 4 4 Fibronectin type III domain ig PF00047.20 KFM03210.1 - 9.2e-36 121.7 0.8 1.9e-05 24.7 0.0 7.9 7 0 0 7 7 7 5 Immunoglobulin domain V-set PF07686.12 KFM03210.1 - 8.3e-30 103.0 0.5 1.1e-05 25.3 0.0 8.1 5 3 1 6 6 6 6 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM03210.1 - 3e-06 27.0 1.1 0.12 12.3 0.0 5.1 5 0 0 5 5 5 1 CD80-like C2-set immunoglobulin domain BiPBP_C PF06832.7 KFM03210.1 - 5.7e-06 26.1 0.0 1.3 9.0 0.0 3.9 3 0 0 3 3 3 2 Penicillin-Binding Protein C-terminus Family Sp38 PF07354.7 KFM03210.1 - 4.3e-05 22.3 0.1 0.012 14.2 0.0 3.3 4 0 0 4 4 4 1 Zona-pellucida-binding protein (Sp38) Interfer-bind PF09294.5 KFM03210.1 - 0.00081 19.3 0.0 0.008 16.1 0.0 2.3 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III C2-set PF05790.10 KFM03210.1 - 0.002 18.0 0.1 8.3 6.4 0.0 4.9 5 0 0 5 5 5 1 Immunoglobulin C2-set domain I-set PF07679.11 KFM03211.1 - 5e-73 241.0 0.0 2.3e-13 49.8 0.0 6.6 6 0 0 6 6 6 6 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM03211.1 - 6.1e-53 176.8 0.0 8.8e-11 41.7 0.0 6.6 6 0 0 6 6 6 6 Immunoglobulin domain fn3 PF00041.16 KFM03211.1 - 2.3e-44 149.4 17.2 3.4e-12 46.3 0.0 5.7 5 0 0 5 5 5 5 Fibronectin type III domain Ig_3 PF13927.1 KFM03211.1 - 2e-43 146.6 0.0 4.3e-07 30.3 0.0 7.1 6 0 0 6 6 6 6 Immunoglobulin domain ig PF00047.20 KFM03211.1 - 4.6e-31 106.7 0.1 7.7e-08 32.3 0.0 7.8 8 0 0 8 8 8 5 Immunoglobulin domain Bravo_FIGEY PF13882.1 KFM03211.1 - 6.6e-26 91.0 8.1 1.8e-25 89.6 5.6 1.8 1 0 0 1 1 1 1 Bravo-like intracellular region V-set PF07686.12 KFM03211.1 - 1.6e-14 53.7 2.4 0.0028 17.5 0.0 7.6 5 5 1 6 6 6 2 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM03211.1 - 1.3e-11 44.2 0.1 0.24 11.3 0.0 6.5 6 0 0 6 6 6 3 CD80-like C2-set immunoglobulin domain BiPBP_C PF06832.7 KFM03211.1 - 2.4e-05 24.1 0.0 0.076 12.9 0.0 4.5 5 0 0 5 5 5 1 Penicillin-Binding Protein C-terminus Family Herpes_gE PF02480.11 KFM03211.1 - 6.1e-05 21.4 0.0 1.6 6.9 0.0 4.0 3 1 1 4 4 4 2 Alphaherpesvirus glycoprotein E V-set_CD47 PF08204.6 KFM03211.1 - 0.0053 16.5 1.6 5.7 6.7 0.0 3.9 4 1 0 4 4 4 1 CD47 immunoglobulin-like domain LRR_8 PF13855.1 KFM03212.1 - 5.2e-50 167.0 34.6 3.5e-13 49.1 1.7 6.7 2 1 4 6 6 6 6 Leucine rich repeat LRR_4 PF12799.2 KFM03212.1 - 1.2e-27 94.9 43.5 5.5e-06 25.8 0.3 8.3 3 2 5 8 8 8 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFM03212.1 - 5.8e-17 61.6 0.0 3.4e-08 33.2 0.0 2.9 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) I-set PF07679.11 KFM03212.1 - 2.6e-14 52.8 0.0 5.2e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_1 PF00560.28 KFM03212.1 - 1e-10 40.0 40.3 0.052 13.5 0.1 12.7 14 0 0 14 14 14 3 Leucine Rich Repeat LRR_9 PF14580.1 KFM03212.1 - 6.9e-09 35.4 11.3 0.0083 15.7 0.6 4.6 1 1 4 5 5 5 4 Leucine-rich repeat Ig_2 PF13895.1 KFM03212.1 - 4.8e-07 29.8 0.0 1.1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain LRR_7 PF13504.1 KFM03212.1 - 2e-06 27.0 30.9 1.1 9.7 0.1 11.7 11 1 1 12 12 12 1 Leucine rich repeat V-set PF07686.12 KFM03212.1 - 2.5e-06 27.3 0.0 5.3e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.1 KFM03212.1 - 4.5e-06 27.0 0.0 1.2e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain LRR_6 PF13516.1 KFM03212.1 - 0.00015 21.4 36.8 0.37 11.0 0.1 11.0 10 3 2 12 12 11 3 Leucine Rich repeat Desmo_N PF06771.6 KFM03212.1 - 0.028 14.3 0.1 0.11 12.4 0.1 2.0 1 0 0 1 1 1 0 Viral Desmoplakin N-terminus zf-C3HC4_3 PF13920.1 KFM03213.1 - 6.4e-10 38.5 6.4 6.4e-10 38.5 4.4 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM03213.1 - 1.5e-05 24.8 7.4 3e-05 23.9 5.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF581 PF04570.9 KFM03213.1 - 0.01 15.1 8.4 2.5 7.4 0.6 3.8 2 1 2 4 4 4 0 Protein of unknown function (DUF581) DZR PF12773.2 KFM03213.1 - 0.044 13.5 2.0 0.12 12.1 1.4 1.8 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_5 PF14634.1 KFM03213.1 - 0.13 12.0 7.5 0.37 10.5 5.2 1.9 1 1 0 1 1 1 0 zinc-RING finger domain UPF0547 PF10571.4 KFM03213.1 - 0.13 11.9 4.1 0.48 10.1 0.7 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-CHY PF05495.7 KFM03213.1 - 0.34 11.0 6.5 0.36 11.0 3.7 1.7 1 1 0 1 1 1 0 CHY zinc finger zf-RING_2 PF13639.1 KFM03213.1 - 0.67 9.8 7.7 1.5 8.7 5.4 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.1 KFM03213.1 - 3.6 7.2 8.3 0.78 9.3 1.9 2.6 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain SWIB PF02201.13 KFM03214.1 - 6.3e-11 41.8 0.0 1.4e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain zf-C3HC4_3 PF13920.1 KFM03214.1 - 5.3e-09 35.6 6.4 5.3e-09 35.6 4.4 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RanBP PF00641.13 KFM03214.1 - 1.8e-05 23.7 8.8 1.8e-05 23.7 6.1 2.3 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others zf-C3HC4_2 PF13923.1 KFM03214.1 - 0.00022 21.2 7.4 0.00022 21.2 5.1 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DZR PF12773.2 KFM03214.1 - 0.42 10.4 17.1 0.99 9.2 1.4 2.8 2 0 0 2 2 2 0 Double zinc ribbon PP1c_bdg PF10488.4 KFM03216.1 - 5.3e-79 265.5 13.6 7e-79 265.2 9.4 1.1 1 0 0 1 1 1 1 Phosphatase-1 catalytic subunit binding region DCA16 PF15349.1 KFM03216.1 - 0.27 10.5 5.8 0.44 9.8 4.0 1.3 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 16 Apt1 PF10351.4 KFM03216.1 - 0.39 9.5 2.5 0.58 8.9 1.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Got1 PF04178.7 KFM03217.1 - 4e-17 62.4 18.4 4.8e-17 62.1 12.8 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Asp PF00026.18 KFM03218.1 - 4.7e-112 374.3 0.0 5.4e-112 374.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KFM03218.1 - 3e-06 27.2 0.0 6.7e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KFM03218.1 - 5.4e-05 22.7 0.0 0.00016 21.2 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal A1_Propeptide PF07966.7 KFM03218.1 - 0.00022 20.9 0.0 0.00039 20.1 0.0 1.4 1 0 0 1 1 1 1 A1 Propeptide Choline_kinase PF01633.15 KFM03219.1 - 3.1e-57 193.5 0.0 4.4e-57 193.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 KFM03219.1 - 4.4e-15 56.0 0.0 5.7e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KFM03219.1 - 8.9e-05 21.7 0.9 0.00028 20.1 0.6 1.8 1 1 0 1 1 1 1 Ecdysteroid kinase Caps_assemb_Wzi PF14052.1 KFM03219.1 - 0.0084 15.0 0.9 0.011 14.6 0.6 1.1 1 0 0 1 1 1 1 Capsule assembly protein Wzi DUF1679 PF07914.6 KFM03219.1 - 0.098 11.2 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) HMG_box PF00505.14 KFM03220.1 - 5.4e-23 81.0 3.5 1e-22 80.1 2.4 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFM03220.1 - 6.2e-09 36.1 1.6 6.2e-09 36.1 1.1 1.9 2 0 0 2 2 2 1 HMG-box domain LSM PF01423.17 KFM03221.1 - 7.9e-18 63.7 0.3 8.8e-18 63.6 0.2 1.0 1 0 0 1 1 1 1 LSM domain E1-E2_ATPase PF00122.15 KFM03223.1 - 1.2e-58 197.8 1.4 2.9e-58 196.6 1.0 1.7 1 1 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFM03223.1 - 9.7e-44 149.0 5.0 4.3e-43 146.9 1.3 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus ATP_Ca_trans_C PF12424.3 KFM03223.1 - 1.1e-28 99.3 0.0 2.7e-28 98.1 0.0 1.7 1 0 0 1 1 1 1 Plasma membrane calcium transporter ATPase C terminal Hydrolase PF00702.21 KFM03223.1 - 6.9e-26 92.0 0.0 1.6e-25 90.8 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFM03223.1 - 2.6e-17 62.5 0.0 6.2e-17 61.3 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KFM03223.1 - 2.5e-16 58.8 0.0 8.7e-16 57.1 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KFM03223.1 - 2e-13 50.9 0.0 4.2e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFM03223.1 - 7.8e-07 28.9 0.1 0.00014 21.5 0.1 2.9 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase LRR_8 PF13855.1 KFM03224.1 - 5.4e-37 125.3 33.4 4.2e-13 48.8 5.1 6.2 2 1 5 7 7 7 7 Leucine rich repeat LRR_4 PF12799.2 KFM03224.1 - 8.8e-33 111.3 36.1 3.2e-08 33.0 2.2 8.1 4 4 2 7 7 7 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM03224.1 - 2.7e-21 72.3 33.9 0.018 15.0 0.0 11.4 10 1 1 11 11 11 7 Leucine Rich Repeat LRR_7 PF13504.1 KFM03224.1 - 1.6e-11 42.3 24.8 0.4 11.0 0.0 10.8 11 0 0 11 11 11 3 Leucine rich repeat LRR_6 PF13516.1 KFM03224.1 - 1.7e-10 39.8 30.1 0.17 12.0 0.0 10.4 10 1 1 11 11 11 3 Leucine Rich repeat LRRNT PF01462.13 KFM03224.1 - 4.7e-06 25.9 3.5 4.7e-06 25.9 2.5 3.6 5 0 0 5 5 5 1 Leucine rich repeat N-terminal domain LRR_5 PF13306.1 KFM03224.1 - 9.3e-06 25.3 1.4 0.0087 15.7 0.0 3.2 1 1 2 3 3 3 2 Leucine rich repeats (6 copies) FNIP PF05725.7 KFM03224.1 - 0.0051 16.7 8.8 3 7.8 0.4 4.3 2 2 1 3 3 3 3 FNIP Repeat LRR_9 PF14580.1 KFM03224.1 - 2 7.9 8.2 8.4 5.9 1.5 3.2 1 1 2 3 3 3 0 Leucine-rich repeat LRR_8 PF13855.1 KFM03225.1 - 5.3e-33 112.5 17.8 8.1e-11 41.5 0.9 5.5 3 2 2 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 KFM03225.1 - 7.5e-26 89.2 21.5 5.4e-07 29.0 0.4 7.4 3 2 3 7 7 7 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM03225.1 - 2.7e-25 84.4 18.2 0.0065 16.3 0.1 11.3 11 0 0 11 11 11 7 Leucine Rich Repeat LRR_6 PF13516.1 KFM03225.1 - 1.7e-15 55.2 19.5 0.24 11.5 0.3 10.7 9 1 1 10 10 10 4 Leucine Rich repeat LRR_7 PF13504.1 KFM03225.1 - 4.7e-14 50.0 19.9 1.2 9.6 0.0 10.5 11 1 1 12 12 12 4 Leucine rich repeat LRR_9 PF14580.1 KFM03225.1 - 6.2e-08 32.3 0.3 0.076 12.5 0.0 3.4 1 1 2 3 3 3 3 Leucine-rich repeat LRRNT PF01462.13 KFM03225.1 - 1.3e-06 27.7 1.9 1.3e-06 27.7 1.3 3.2 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_5 PF13306.1 KFM03225.1 - 2.3e-06 27.3 3.1 3.5e-05 23.5 0.0 2.6 2 2 0 2 2 2 1 Leucine rich repeats (6 copies) FNIP PF05725.7 KFM03225.1 - 0.00031 20.6 1.8 1.3 9.0 0.0 4.5 3 3 2 5 5 5 1 FNIP Repeat BTG PF07742.7 KFM03226.1 - 4e-38 129.5 0.0 4.7e-38 129.3 0.0 1.1 1 0 0 1 1 1 1 BTG family SHIPPO-rpt PF07004.7 KFM03227.1 - 0.00018 22.2 6.9 0.082 13.8 0.0 4.3 4 1 0 4 4 4 2 Sperm-tail PG-rich repeat ECR1_N PF14382.1 KFM03227.1 - 0.0032 16.7 0.0 0.009 15.2 0.0 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region SHIPPO-rpt PF07004.7 KFM03228.1 - 0.00084 20.1 8.3 0.095 13.6 0.1 4.3 4 1 0 4 4 4 1 Sperm-tail PG-rich repeat ECR1_N PF14382.1 KFM03228.1 - 0.0039 16.4 0.0 0.01 15.0 0.0 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Bromo_TP PF07524.8 KFM03229.1 - 1.9e-30 104.4 0.7 5e-30 103.0 0.2 1.8 2 0 0 2 2 2 1 Bromodomain associated TAF8_C PF10406.4 KFM03229.1 - 5.6e-25 87.1 1.1 1.3e-24 86.0 0.7 1.7 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term CENP-S PF15630.1 KFM03229.1 - 0.01 15.9 0.0 0.026 14.7 0.0 1.8 1 0 0 1 1 1 0 Kinetochore component CENP-S TFIID-31kDa PF02291.10 KFM03229.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DUF3090 PF11290.3 KFM03229.1 - 0.028 13.9 0.3 0.081 12.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3090) CBFD_NFYB_HMF PF00808.18 KFM03229.1 - 0.037 14.0 0.1 0.073 13.1 0.1 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 KFM03229.1 - 0.093 12.6 0.3 0.22 11.4 0.0 1.7 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) Cyclin_N PF00134.18 KFM03230.1 - 2.2e-28 98.3 0.4 2.2e-28 98.3 0.3 1.5 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFM03230.1 - 4.8e-20 71.6 1.7 1.2e-19 70.3 0.6 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain K-cyclin_vir_C PF09080.5 KFM03230.1 - 0.00026 21.1 0.6 0.00043 20.4 0.4 1.3 1 0 0 1 1 1 1 K cyclin, C terminal Herp-Cyclin PF09241.5 KFM03230.1 - 0.0091 16.2 0.3 0.017 15.4 0.1 1.5 2 0 0 2 2 2 1 Herpesviridae viral cyclin Bystin PF05291.6 KFM03231.1 - 2.7e-142 473.1 0.4 3.3e-142 472.8 0.2 1.0 1 0 0 1 1 1 1 Bystin Med20 PF08612.6 KFM03232.1 - 1.1e-36 126.1 0.0 1.2e-36 125.9 0.0 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex UCH PF00443.24 KFM03233.1 - 7.8e-63 212.1 3.8 9.4e-63 211.8 0.3 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KFM03233.1 - 3.3e-21 75.1 7.2 3.3e-21 75.1 5.0 2.9 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 KFM03233.1 - 2e-19 70.1 8.3 2.3e-15 56.8 0.2 2.7 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUF2955 PF11168.3 KFM03233.1 - 0.25 10.9 0.0 0.42 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2955) ArfGap PF01412.13 KFM03233.1 - 0.27 11.0 7.2 0.088 12.5 2.0 2.4 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf LIM PF00412.17 KFM03234.1 - 2.3e-30 104.4 32.9 3.8e-12 46.0 2.2 3.7 3 1 0 3 3 3 3 LIM domain PET PF06297.9 KFM03234.1 - 4.7e-11 42.2 0.2 7.5e-11 41.6 0.1 1.3 1 0 0 1 1 1 1 PET Domain Med27 PF11571.3 KFM03234.1 - 9 6.4 17.5 2.2 8.4 0.0 3.8 3 1 1 4 4 4 0 Mediator complex subunit 27 IRS PF02174.12 KFM03235.1 - 1.2e-28 98.6 0.0 2.6e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 PTB domain (IRS-1 type) Asp PF00026.18 KFM03236.1 - 5.6e-109 364.2 1.2 6.5e-109 364.0 0.9 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease A1_Propeptide PF07966.7 KFM03236.1 - 1.8e-10 40.1 1.0 3.2e-10 39.4 0.7 1.4 1 0 0 1 1 1 1 A1 Propeptide TAXi_N PF14543.1 KFM03236.1 - 2.4e-08 34.0 0.4 9.6e-08 32.1 0.1 2.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KFM03236.1 - 7.8e-07 28.7 0.0 7.5e-06 25.5 0.0 2.5 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 KFM03236.1 - 2.8e-05 24.5 0.0 0.0024 18.3 0.0 2.6 2 0 0 2 2 2 1 Aspartyl protease MDFI PF15316.1 KFM03237.1 - 2e-59 200.5 48.5 2.1e-59 200.4 33.6 1.0 1 0 0 1 1 1 1 MyoD family inhibitor V-set PF07686.12 KFM03238.1 - 4.3e-11 42.7 0.7 6.9e-11 42.0 0.5 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain CBFB_NFYA PF02045.10 KFM03239.1 - 3e-28 98.1 9.3 5.2e-28 97.3 6.4 1.4 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Packaging_FI PF14000.1 KFM03239.1 - 3.8 7.7 7.5 0.64 10.2 0.8 2.6 2 1 0 2 2 2 0 DNA packaging protein FI Macro PF01661.16 KFM03240.1 - 3.8e-09 36.4 0.0 6e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Macro domain APOBEC_N PF08210.6 KFM03241.1 - 1.1e-45 155.5 1.3 1.4e-45 155.2 0.9 1.1 1 0 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC_C PF05240.9 KFM03241.1 - 1.5e-20 72.3 1.6 2.5e-20 71.5 1.1 1.4 1 0 0 1 1 1 1 APOBEC-like C-terminal domain dCMP_cyt_deam_1 PF00383.17 KFM03241.1 - 9.3e-05 22.0 0.1 0.00018 21.0 0.0 1.5 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MH1 PF03165.11 KFM03241.1 - 0.054 13.5 0.1 0.084 12.8 0.1 1.4 1 0 0 1 1 1 0 MH1 domain MafB19-deam PF14437.1 KFM03241.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 MafB19-like deaminase TspO_MBR PF03073.10 KFM03242.1 - 1.1e-47 161.2 9.4 1.3e-47 161.0 6.5 1.0 1 0 0 1 1 1 1 TspO/MBR family Bcl-2 PF00452.14 KFM03243.1 - 2.4e-27 95.0 0.1 5.7e-27 93.7 0.0 1.7 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family Bcl-2_3 PF15286.1 KFM03243.1 - 0.0047 17.3 0.2 0.014 15.8 0.0 1.8 1 1 1 2 2 2 1 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like IPK PF03770.11 KFM03245.1 - 1.6e-24 86.6 0.4 2.3e-24 86.1 0.3 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase MSC PF09402.5 KFM03246.1 - 1.9e-45 155.0 1.6 1.9e-45 155.0 1.1 1.4 2 0 0 2 2 2 1 Man1-Src1p-C-terminal domain Post_transc_reg PF13797.1 KFM03246.1 - 0.067 12.8 0.5 0.16 11.5 0.4 1.6 1 0 0 1 1 1 0 Post-transcriptional regulator Motilin_assoc PF04643.7 KFM03247.1 - 8.6e-08 31.5 0.0 1.4e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Motilin/ghrelin-associated peptide Motilin_ghrelin PF04644.7 KFM03247.1 - 2.6e-06 27.0 0.8 4.6e-06 26.3 0.6 1.4 1 0 0 1 1 1 1 Motilin/ghrelin PP28 PF10252.4 KFM03247.1 - 0.075 13.0 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 La PF05383.12 KFM03247.1 - 0.13 12.0 0.1 0.32 10.8 0.0 1.8 2 0 0 2 2 2 0 La domain 7tm_1 PF00001.16 KFM03248.1 - 4.7e-49 166.8 13.9 7.1e-49 166.2 9.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Rhodopsin_N PF10413.4 KFM03248.1 - 1.2e-24 85.6 3.2 2.9e-24 84.4 2.2 1.7 1 0 0 1 1 1 1 Amino terminal of the G-protein receptor rhodopsin 7TM_GPCR_Srw PF10324.4 KFM03248.1 - 3.5e-11 42.7 14.4 2e-10 40.3 10.0 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.4 KFM03248.1 - 1.2e-06 27.9 16.9 1.8e-06 27.3 11.7 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.4 KFM03248.1 - 2.9e-05 23.3 16.5 4.5e-05 22.7 11.4 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF2214 PF09980.4 KFM03248.1 - 0.0085 15.8 2.1 0.055 13.2 0.1 2.4 2 0 0 2 2 2 1 Predicted membrane protein (DUF2214) Git3 PF11710.3 KFM03248.1 - 0.13 11.8 12.9 0.015 14.8 5.2 2.3 2 1 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 60KD_IMP PF02096.15 KFM03248.1 - 0.78 9.3 7.4 0.2 11.3 2.3 2.1 1 1 1 2 2 2 0 60Kd inner membrane protein DUF4079 PF13301.1 KFM03248.1 - 1.3 8.9 5.8 1.1 9.2 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) DUF2569 PF10754.4 KFM03248.1 - 2.9 8.1 15.8 1.9 8.7 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2569) DUF996 PF06195.8 KFM03248.1 - 3 7.8 9.4 0.096 12.6 1.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF996) FA_desaturase PF00487.19 KFM03248.1 - 4.2 6.7 14.6 2.1 7.7 0.3 2.7 1 1 2 3 3 3 0 Fatty acid desaturase ANF_receptor PF01094.23 KFM03249.1 - 3.9e-101 338.3 0.0 4.9e-101 337.9 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.17 KFM03249.1 - 2.2e-85 285.8 16.0 3e-85 285.3 11.1 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.9 KFM03249.1 - 2.4e-14 52.7 10.6 4.9e-14 51.7 7.4 1.6 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.1 KFM03249.1 - 1.2e-11 44.5 0.0 6.5e-11 42.1 0.0 1.9 1 1 0 1 1 1 1 Periplasmic binding protein DUF336 PF03928.9 KFM03249.1 - 0.068 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF336) NUDIX PF00293.23 KFM03250.1 - 5.1e-16 58.5 0.3 6e-16 58.3 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain S10_plectin PF03501.10 KFM03251.1 - 9.7e-46 153.5 0.2 1.2e-45 153.3 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain FCH PF00611.18 KFM03252.1 - 1.6e-22 79.4 0.2 1.6e-22 79.4 0.2 3.1 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 KFM03252.1 - 1.3e-16 59.9 0.3 2.8e-16 58.8 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM03252.1 - 1.2e-14 53.4 0.1 2.2e-14 52.5 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFM03252.1 - 1.3e-07 30.9 0.0 2.4e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain KAP_NTPase PF07693.9 KFM03252.1 - 0.043 12.8 1.8 0.056 12.4 1.3 1.2 1 0 0 1 1 1 0 KAP family P-loop domain PAP_central PF04928.12 KFM03252.1 - 0.33 9.7 3.8 0.7 8.6 2.7 1.6 1 0 0 1 1 1 0 Poly(A) polymerase central domain LOH1CR12 PF10158.4 KFM03252.1 - 0.57 9.9 6.3 0.41 10.4 2.1 2.2 2 1 0 2 2 2 0 Tumour suppressor protein V_ATPase_I PF01496.14 KFM03252.1 - 1.8 6.3 7.8 2.1 6.0 5.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Laminin_II PF06009.7 KFM03252.1 - 1.8 8.3 9.4 0.17 11.6 2.5 2.1 2 1 0 2 2 2 0 Laminin Domain II Tho2 PF11262.3 KFM03252.1 - 3.6 6.5 15.0 1.5 7.8 6.5 2.6 2 1 1 3 3 3 0 Transcription factor/nuclear export subunit protein 2 Phlebovirus_NSM PF07246.6 KFM03252.1 - 8.4 5.4 10.8 13 4.7 7.3 1.5 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Ets PF00178.17 KFM03253.1 - 2.8e-28 97.8 0.1 4.3e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 Ets-domain zf-U1 PF06220.7 KFM03255.1 - 1.6e-20 72.3 8.3 2.1e-20 71.9 5.8 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 KFM03255.1 - 0.011 15.7 9.9 0.079 13.1 6.8 2.0 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM03255.1 - 1 9.6 5.4 10 6.5 3.8 2.1 1 1 0 1 1 1 0 Zinc-finger of C2H2 type Chorein_N PF12624.2 KFM03256.1 - 4.4e-12 45.5 0.1 6.2e-10 38.6 0.0 2.7 2 0 0 2 2 2 2 N-terminal region of Chorein, a TM vesicle-mediated sorter TAFII28 PF04719.9 KFM03257.1 - 1.5e-38 130.4 0.0 2.6e-38 129.6 0.0 1.4 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.18 KFM03257.1 - 2.8e-06 27.2 0.1 5.8e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KFM03257.1 - 0.0031 17.6 0.0 0.0059 16.7 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Cdc6_C PF09079.6 KFM03257.1 - 0.082 12.6 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 CDC6, C terminal SRP_SPB PF02978.14 KFM03257.1 - 0.11 12.7 2.5 0.29 11.3 1.8 1.7 1 1 0 1 1 1 0 Signal peptide binding domain SpoU_sub_bind PF08032.7 KFM03257.1 - 0.62 10.2 2.5 15 5.7 0.3 2.8 2 1 1 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding Ank PF00023.25 KFM03258.1 - 5.7e-48 158.4 15.5 1.5e-07 30.8 0.3 7.0 6 0 0 6 6 6 6 Ankyrin repeat Ank_2 PF12796.2 KFM03258.1 - 4.6e-46 155.0 9.6 1.9e-15 56.9 0.3 3.9 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFM03258.1 - 2.7e-43 145.0 16.6 1e-09 38.2 0.0 6.6 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM03258.1 - 8.8e-41 133.8 6.2 1.4e-06 27.9 0.0 6.9 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 KFM03258.1 - 1.1e-39 134.1 10.6 1.8e-11 44.2 0.0 6.1 3 1 4 7 7 7 7 Ankyrin repeats (many copies) PID PF00640.18 KFM03258.1 - 2e-30 105.5 0.4 4.4e-30 104.5 0.3 1.6 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SAM_1 PF00536.25 KFM03258.1 - 3.8e-30 103.8 0.1 7.7e-15 54.8 0.0 2.5 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFM03258.1 - 3.4e-24 84.4 0.2 7.9e-13 48.0 0.1 2.5 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) PTB PF08416.8 KFM03258.1 - 0.0023 17.8 0.0 0.0045 16.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PID_2 PF14719.1 KFM03258.1 - 0.06 12.9 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) Ribosomal_L1 PF00687.16 KFM03259.1 - 2.7e-37 128.2 3.2 3e-37 128.1 2.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family TetR PF13972.1 KFM03259.1 - 0.11 11.9 0.1 0.3 10.5 0.0 1.6 2 0 0 2 2 2 0 Bacterial transcriptional repressor zf-H2C2_2 PF13465.1 KFM03260.1 - 1.5e-42 141.8 47.0 2.7e-09 36.8 0.3 7.3 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.21 KFM03260.1 - 1.5e-29 100.4 45.8 4.5e-06 26.6 0.2 7.4 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM03260.1 - 6e-23 79.4 37.0 0.00065 19.8 0.1 7.3 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM03260.1 - 1.1e-07 31.7 15.8 0.17 12.1 0.0 6.6 7 0 0 7 7 7 2 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 KFM03260.1 - 0.0002 21.6 0.5 0.0002 21.6 0.4 3.9 3 1 1 4 4 4 1 TRAF-type zinc finger CopK PF11525.3 KFM03260.1 - 0.012 15.2 0.2 25 4.6 0.0 4.3 2 1 3 5 5 5 0 Copper resistance protein K zf-C2H2_6 PF13912.1 KFM03260.1 - 0.04 13.8 0.4 0.04 13.8 0.3 5.2 6 0 0 6 6 6 0 C2H2-type zinc finger zf-met PF12874.2 KFM03260.1 - 1.8 8.9 18.5 0.72 10.1 0.1 5.1 5 0 0 5 5 5 0 Zinc-finger of C2H2 type PH PF00169.24 KFM03261.1 - 3e-16 59.5 0.4 1.8e-15 57.0 0.4 2.3 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 KFM03261.1 - 0.00061 20.0 13.4 0.067 13.4 9.3 3.7 1 1 0 1 1 1 1 Pleckstrin homology domain CagX PF03524.10 KFM03261.1 - 0.014 14.6 0.7 0.014 14.6 0.5 2.3 2 1 0 2 2 2 0 Conjugal transfer protein EF-hand_6 PF13405.1 KFM03261.1 - 0.094 12.6 0.0 0.39 10.7 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain Hormone_recep PF00104.25 KFM03262.1 - 1.3e-29 102.7 0.0 2.2e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFM03262.1 - 2e-28 98.4 16.9 3.8e-28 97.5 11.7 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) zf-RING_2 PF13639.1 KFM03263.1 - 5.6e-06 26.0 2.2 5.6e-06 26.0 1.5 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KFM03263.1 - 8.4e-06 25.3 1.4 1.9e-05 24.2 0.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM03263.1 - 0.00045 19.8 1.0 0.001 18.7 0.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFM03263.1 - 0.0014 18.4 2.6 0.0031 17.3 1.8 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KFM03263.1 - 0.0016 18.5 1.8 0.0021 18.0 0.6 1.7 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KFM03263.1 - 0.0022 17.9 3.1 0.0022 17.9 2.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM03263.1 - 0.0079 15.8 1.3 0.0079 15.8 0.9 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFM03263.1 - 0.035 13.9 0.6 0.035 13.9 0.4 1.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger FA_FANCE PF11510.3 KFM03264.1 - 3.5e-67 226.3 15.4 5.2e-67 225.7 10.7 1.2 1 0 0 1 1 1 1 Fanconi Anaemia group E protein FANCE MRVI1 PF05781.7 KFM03265.1 - 5.6e-49 166.9 0.4 6.9e-49 166.6 0.3 1.0 1 0 0 1 1 1 1 MRVI1 protein FHIPEP PF00771.15 KFM03265.1 - 0.019 13.3 0.2 0.03 12.6 0.2 1.3 1 0 0 1 1 1 0 FHIPEP family CENP-Q PF13094.1 KFM03265.1 - 0.039 13.9 1.0 0.039 13.9 0.7 1.9 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit FmrO PF07091.6 KFM03265.1 - 0.19 10.6 2.4 0.24 10.3 1.3 1.4 1 1 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Peptidase_C6 PF00851.13 KFM03265.1 - 0.32 9.5 4.3 0.4 9.2 3.0 1.0 1 0 0 1 1 1 0 Helper component proteinase AAA_33 PF13671.1 KFM03265.1 - 0.54 10.1 4.5 0.25 11.1 0.3 2.1 2 0 0 2 2 2 0 AAA domain DUF3585 PF12130.3 KFM03267.1 - 1.8e-33 115.3 19.2 2.7e-33 114.7 13.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3585) CH PF00307.26 KFM03267.1 - 4.9e-17 61.9 0.0 1.4e-16 60.5 0.0 1.8 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFM03267.1 - 1e-10 41.0 0.0 1.9e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain DsrC PF04358.8 KFM03267.1 - 0.011 16.0 0.3 0.78 10.0 0.0 2.5 2 0 0 2 2 2 0 DsrC like protein Exo_endo_phos PF03372.18 KFM03268.1 - 5.3e-16 59.2 0.0 6.9e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KFM03268.1 - 0.15 11.6 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase TEA PF01285.13 KFM03269.1 - 1e-155 519.1 0.0 1.3e-155 518.8 0.0 1.1 1 0 0 1 1 1 1 TEA/ATTS domain family Rotamase_2 PF13145.1 KFM03269.1 - 0.0069 17.0 0.0 0.014 16.0 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain CLAMP PF14769.1 KFM03269.1 - 0.091 12.9 1.9 4.1 7.6 0.7 2.3 2 0 0 2 2 2 0 Flagellar C1a complex subunit C1a-32 Tub PF01167.13 KFM03270.1 - 8.6e-116 385.1 0.0 9.8e-116 384.9 0.0 1.0 1 0 0 1 1 1 1 Tub family FKBP_C PF00254.23 KFM03271.1 - 1.6e-31 108.1 0.0 1.8e-14 53.4 0.0 2.5 2 1 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_11 PF13414.1 KFM03271.1 - 9.4e-18 63.6 4.3 2.6e-13 49.3 1.4 2.6 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KFM03271.1 - 7.4e-15 53.8 14.1 1.2e-08 34.1 1.3 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFM03271.1 - 3.5e-11 42.1 7.9 1.7e-05 24.3 0.8 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFM03271.1 - 9.8e-09 34.3 6.0 0.00024 20.6 0.2 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFM03271.1 - 4.9e-07 29.5 1.1 0.0012 18.7 0.6 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFM03271.1 - 2.4e-06 27.7 0.3 0.00024 21.3 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFM03271.1 - 6.7e-06 25.5 0.3 3.2e-05 23.4 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFM03271.1 - 8.5e-06 25.5 0.4 3e-05 23.8 0.1 2.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KFM03271.1 - 0.00012 21.9 1.9 0.012 15.4 0.2 2.5 1 1 1 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 KFM03271.1 - 0.00027 21.2 1.9 0.072 13.5 0.2 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFM03271.1 - 0.00031 21.3 0.5 0.0026 18.3 0.2 2.5 2 1 1 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 KFM03271.1 - 0.0047 17.0 6.0 0.036 14.1 1.6 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 KFM03271.1 - 0.011 16.3 0.1 0.056 14.1 0.1 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 KFM03271.1 - 0.12 12.5 2.7 20 5.6 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Colipase PF01114.13 KFM03272.1 - 3.6e-22 77.5 5.5 5.9e-22 76.8 3.8 1.3 1 0 0 1 1 1 1 Colipase, N-terminal domain Colipase_C PF02740.9 KFM03272.1 - 1.3e-10 40.7 2.0 1.3e-10 40.7 1.4 2.3 3 0 0 3 3 3 1 Colipase, C-terminal domain Metallothi_Euk2 PF12809.2 KFM03272.1 - 0.0011 19.2 9.0 0.0013 19.0 6.2 1.1 1 0 0 1 1 1 1 Eukaryotic metallothionein Colipase-like PF15083.1 KFM03272.1 - 0.0017 18.2 3.2 0.002 18.0 2.2 1.1 1 0 0 1 1 1 1 Colipase-like Pkinase PF00069.20 KFM03273.1 - 9.5e-40 136.3 3.4 2.3e-22 79.4 0.0 3.2 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFM03273.1 - 5.5e-14 51.8 0.2 4.8e-10 38.9 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase NARP1 PF12569.3 KFM03273.1 - 2 7.0 8.0 4.3 5.9 5.5 1.5 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Sulfate_transp PF00916.15 KFM03274.1 - 2.8e-45 154.4 14.7 2.8e-45 154.4 10.2 2.1 3 0 0 3 3 3 1 Sulfate transporter family STAS PF01740.16 KFM03274.1 - 2.2e-21 75.4 0.0 8.6e-21 73.5 0.0 1.9 1 1 0 1 1 1 1 STAS domain Sulfate_tra_GLY PF13792.1 KFM03274.1 - 6.3e-18 64.2 1.8 9.6e-18 63.6 0.1 2.4 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif Pkinase PF00069.20 KFM03275.1 - 1.7e-69 233.8 0.0 2e-69 233.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM03275.1 - 2.1e-31 108.9 0.0 2.6e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFM03275.1 - 4.6e-05 22.5 0.1 7.1e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFM03275.1 - 0.006 16.3 0.3 0.029 14.0 0.0 2.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KFM03275.1 - 0.042 12.8 0.0 0.063 12.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.20 KFM03276.1 - 8.2e-73 244.7 0.0 1.1e-72 244.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM03276.1 - 9.1e-31 106.8 0.1 1.3e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFM03276.1 - 3.5e-05 23.6 0.2 0.00012 21.9 0.0 1.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 KFM03276.1 - 3.8e-05 22.8 0.0 6e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KFM03276.1 - 0.00043 19.3 0.0 0.0031 16.5 0.0 2.3 2 1 1 3 3 3 1 Kinase-like DUF3754 PF12576.3 KFM03276.1 - 0.0047 16.5 0.1 0.019 14.5 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3754) zf-HC5HC2H_2 PF13832.1 KFM03277.1 - 4.6e-38 129.5 5.8 4.6e-38 129.5 4.0 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.4 KFM03277.1 - 2.3e-35 122.2 0.8 2.3e-35 122.2 0.6 2.8 3 0 0 3 3 3 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.1 KFM03277.1 - 1.4e-26 92.4 3.9 1.4e-26 92.4 2.7 3.2 3 0 0 3 3 3 1 PHD-like zinc-binding domain Bromodomain PF00439.20 KFM03277.1 - 5.1e-19 67.9 0.1 1.9e-18 66.1 0.1 2.0 1 0 0 1 1 1 1 Bromodomain PWWP PF00855.12 KFM03277.1 - 6.5e-14 51.8 0.0 2.2e-13 50.2 0.0 1.9 1 0 0 1 1 1 1 PWWP domain PHD_2 PF13831.1 KFM03277.1 - 4.1e-12 45.1 6.6 4.1e-12 45.1 4.6 2.6 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 KFM03277.1 - 2.8e-06 26.9 28.3 0.00051 19.6 11.8 2.8 2 0 0 2 2 2 2 PHD-finger DNA_topoisoIV PF00521.15 KFM03277.1 - 0.049 12.4 3.2 0.11 11.3 2.2 1.5 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Elf-1_N PF12310.3 KFM03277.1 - 0.1 12.5 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 Transcription factor protein N terminal C1_1 PF00130.17 KFM03277.1 - 0.16 11.7 18.6 0.013 15.2 4.3 2.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RabGAP-TBC PF00566.13 KFM03278.1 - 7.3e-51 172.6 2.9 1e-50 172.2 2.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.20 KFM03279.1 - 1.6e-47 161.8 0.0 3.4e-47 160.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM03279.1 - 1.6e-12 47.0 0.0 2.7e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM03279.1 - 5.3e-08 32.1 0.0 6e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFM03279.1 - 2.7e-07 29.8 0.0 3.9e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFM03279.1 - 0.0097 15.6 0.4 0.021 14.5 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFM03279.1 - 0.096 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase RecR PF02132.10 KFM03279.1 - 0.099 12.0 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 RecR protein RIO1 PF01163.17 KFM03279.1 - 0.16 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.6 KFM03279.1 - 0.16 10.7 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Mito_carr PF00153.22 KFM03280.1 - 1.1e-10 41.0 0.2 4.2e-05 23.1 0.0 2.8 3 0 0 3 3 3 2 Mitochondrial carrier protein DUF457 PF04307.9 KFM03280.1 - 0.54 9.5 3.6 1.1 8.5 2.4 1.5 1 1 0 1 1 1 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) CAP PF00188.21 KFM03281.1 - 8.7e-21 74.6 0.3 1.3e-20 74.1 0.2 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PXA PF02194.10 KFM03283.1 - 1.6e-33 115.8 0.0 5.2e-33 114.1 0.0 1.9 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 KFM03283.1 - 9.7e-25 86.8 0.6 1.2e-23 83.3 0.3 2.5 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 KFM03283.1 - 5.1e-19 68.1 0.2 1e-18 67.1 0.1 1.5 1 0 0 1 1 1 1 PX domain DUF2448 PF10476.4 KFM03283.1 - 0.013 15.0 0.5 0.06 12.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2448) ADAM_spacer1 PF05986.9 KFM03284.1 - 7.1e-34 116.0 0.0 1.2e-33 115.3 0.0 1.4 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Reprolysin PF01421.14 KFM03284.1 - 3.4e-17 62.6 0.0 3.4e-17 62.6 0.0 1.8 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease TSP_1 PF00090.14 KFM03284.1 - 9.1e-17 60.9 35.4 1.2e-07 31.7 2.4 5.8 5 0 0 5 5 5 3 Thrombospondin type 1 domain Reprolysin_5 PF13688.1 KFM03284.1 - 1.7e-12 47.6 0.0 2.7e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KFM03284.1 - 3.8e-09 37.1 0.0 6.2e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFM03284.1 - 6.2e-06 26.3 0.0 1e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFM03284.1 - 1.8e-05 24.3 0.0 3.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM_spacer1 PF05986.9 KFM03285.1 - 8e-31 106.2 0.0 1.2e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Reprolysin PF01421.14 KFM03285.1 - 5.5e-19 68.5 0.0 8e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease TSP_1 PF00090.14 KFM03285.1 - 1.7e-15 56.8 60.0 6.9e-09 35.6 5.1 6.1 6 0 0 6 6 6 3 Thrombospondin type 1 domain Reprolysin_3 PF13582.1 KFM03285.1 - 8.7e-12 45.6 1.0 9.5e-12 45.5 0.0 1.6 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KFM03285.1 - 6.8e-10 39.1 0.1 1.3e-09 38.2 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KFM03285.1 - 3.7e-08 33.1 0.0 6.8e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFM03285.1 - 1.9e-07 31.3 0.0 3.2e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KFM03285.1 - 0.078 12.6 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Matrixin BTB PF00651.26 KFM03286.1 - 1.9e-29 101.8 0.7 3.3e-29 101.0 0.5 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.21 KFM03286.1 - 4.1e-18 64.5 24.1 0.00016 21.8 0.2 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM03286.1 - 2.4e-16 58.7 19.3 0.00021 21.3 0.6 5.0 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFM03286.1 - 6.4e-14 51.4 22.8 2.5e-06 27.4 0.2 5.1 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_6 PF13912.1 KFM03286.1 - 8.7e-11 41.3 14.6 0.0045 16.8 0.1 5.0 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 KFM03286.1 - 4e-10 39.5 19.9 0.023 14.8 0.2 5.6 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFM03286.1 - 4.4e-09 36.2 10.1 0.043 13.9 0.0 4.7 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFM03286.1 - 9.5e-05 22.4 13.0 0.31 11.1 1.8 4.1 1 1 3 4 4 4 2 C2H2 type zinc-finger (2 copies) Glyco_transf_10 PF00852.14 KFM03286.1 - 0.0057 15.2 0.8 0.07 11.6 0.2 2.3 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) DUF3342 PF11822.3 KFM03286.1 - 0.17 10.9 6.7 0.39 9.8 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3342) Zn_Tnp_IS1595 PF12760.2 KFM03286.1 - 0.18 11.6 19.8 0.074 12.8 2.6 3.4 1 1 2 3 3 3 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 KFM03286.1 - 0.4 10.6 17.0 0.54 10.2 2.0 4.6 3 1 1 4 4 4 0 Zinc ribbon domain DUF678 PF05077.7 KFM03286.1 - 0.5 10.3 6.2 0.33 10.9 0.3 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF678) zf-TFIIB PF13453.1 KFM03286.1 - 0.88 8.8 8.5 0.22 10.7 0.7 3.1 3 0 0 3 3 3 0 Transcription factor zinc-finger CpXC PF14353.1 KFM03286.1 - 2.7 7.9 9.7 68 3.4 0.3 3.7 1 1 1 2 2 2 0 CpXC protein LIM PF00412.17 KFM03286.1 - 3.2 7.8 12.5 0.56 10.3 3.8 3.2 3 1 0 3 3 3 0 LIM domain C1_1 PF00130.17 KFM03286.1 - 4.7 7.0 10.0 0.94 9.2 2.4 2.9 2 1 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_4 PF13717.1 KFM03286.1 - 5.9 6.6 12.8 16 5.2 0.1 4.4 4 0 0 4 4 4 0 zinc-ribbon domain Trypsin PF00089.21 KFM03287.1 - 9.5e-66 221.5 0.2 1.9e-65 220.5 0.2 1.5 1 0 0 1 1 1 1 Trypsin Ldl_recept_a PF00057.13 KFM03287.1 - 3.1e-38 129.3 73.5 6.4e-11 41.9 9.5 4.6 4 0 0 4 4 4 4 Low-density lipoprotein receptor domain class A CUB PF00431.15 KFM03287.1 - 1.6e-37 127.9 0.5 4.1e-20 71.8 0.2 2.6 2 0 0 2 2 2 2 CUB domain SEA PF01390.15 KFM03287.1 - 3.1e-18 65.4 0.0 7.1e-18 64.2 0.0 1.6 1 0 0 1 1 1 1 SEA domain DUF1986 PF09342.6 KFM03287.1 - 3.5e-06 26.5 0.0 1e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) CUB_2 PF02408.15 KFM03287.1 - 4.5e-05 22.9 2.9 0.00043 19.8 0.5 2.6 2 0 0 2 2 2 1 CUB-like domain NFRKB_winged PF14465.1 KFM03288.1 - 1.9e-29 101.4 0.7 1.5e-27 95.3 1.1 3.2 2 1 0 2 2 2 1 NFRKB Winged Helix-like zf-C2H2 PF00096.21 KFM03289.1 - 1.4e-30 103.7 79.7 0.0004 20.5 1.9 10.7 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM03289.1 - 4.8e-24 82.8 65.8 0.0088 16.3 2.9 10.7 10 0 0 10 10 10 10 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFM03289.1 - 1.2e-16 60.0 67.5 0.0016 18.6 1.0 11.8 11 1 0 11 11 11 8 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFM03289.1 - 2.3e-15 56.1 55.7 0.0007 19.6 0.0 10.2 11 0 0 11 11 11 7 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFM03289.1 - 4.2e-10 39.1 45.7 0.012 15.4 0.4 8.8 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KFM03289.1 - 1.2e-08 34.9 46.1 0.21 11.6 0.2 9.4 5 2 4 9 9 9 7 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KFM03289.1 - 7.5e-06 25.9 2.5 0.0022 18.1 0.0 9.3 9 0 0 9 9 9 3 Zinc-finger of C2H2 type zf-Di19 PF05605.7 KFM03289.1 - 6.2e-05 23.0 40.6 0.028 14.5 1.0 7.8 7 1 1 8 8 8 4 Drought induced 19 protein (Di19), zinc-binding DUF629 PF04780.7 KFM03289.1 - 0.086 11.3 35.9 0.21 10.0 0.7 6.8 5 2 2 7 7 7 0 Protein of unknown function (DUF629) APP_E2 PF12925.2 KFM03290.1 - 2.3e-72 242.6 18.1 5e-72 241.5 12.6 1.5 1 0 0 1 1 1 1 E2 domain of amyloid precursor protein APP_N PF02177.11 KFM03290.1 - 1.1e-41 140.9 0.8 1.1e-41 140.9 0.5 2.3 2 0 0 2 2 2 1 Amyloid A4 N-terminal heparin-binding APP_amyloid PF10515.4 KFM03290.1 - 2.5e-30 104.4 1.0 6.6e-30 103.1 0.2 2.2 2 0 0 2 2 2 1 beta-amyloid precursor protein C-terminus APP_Cu_bd PF12924.2 KFM03290.1 - 7e-28 96.9 9.9 1.3e-27 96.0 4.3 2.8 2 0 0 2 2 2 1 Copper-binding of amyloid precursor, CuBD Kunitz_BPTI PF00014.18 KFM03290.1 - 4.7e-20 71.5 5.7 4.7e-20 71.5 3.9 2.0 2 0 0 2 2 2 1 Kunitz/Bovine pancreatic trypsin inhibitor domain DUF2645 PF10840.3 KFM03291.1 - 0.012 15.7 0.1 0.013 15.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2645) DUF716 PF04819.7 KFM03292.1 - 2.3e-33 114.5 3.2 2.3e-33 114.5 2.3 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF716) DUF716 PF04819.7 KFM03293.1 - 4.2e-39 133.0 8.7 7e-39 132.3 6.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF716) TnpB_IS66 PF05717.8 KFM03293.1 - 0.093 12.1 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 IS66 Orf2 like protein RhoGAP PF00620.22 KFM03294.1 - 4.6e-45 152.9 0.1 9.2e-45 151.9 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain PX PF00787.19 KFM03294.1 - 0.00014 21.6 0.1 0.0007 19.3 0.0 2.2 2 0 0 2 2 2 1 PX domain IRK PF01007.15 KFM03295.1 - 1.5e-166 553.3 0.9 1.8e-166 553.0 0.6 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 KFM03295.1 - 0.0015 18.2 8.2 0.0043 16.7 5.7 1.8 1 1 0 1 1 1 1 Ion channel Ion_trans PF00520.26 KFM03295.1 - 0.22 10.7 6.0 0.32 10.2 4.2 1.2 1 0 0 1 1 1 0 Ion transport protein IRK PF01007.15 KFM03296.1 - 2.8e-149 496.4 2.7 3.2e-149 496.3 1.8 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 KFM03296.1 - 0.25 11.0 7.4 0.39 10.4 4.3 1.9 1 1 1 2 2 2 0 Ion channel Ets PF00178.17 KFM03297.1 - 1.3e-39 134.1 0.7 1.3e-39 134.1 0.5 1.8 2 0 0 2 2 2 1 Ets-domain SAM_PNT PF02198.11 KFM03297.1 - 2.1e-26 91.4 0.2 5.2e-26 90.2 0.1 1.7 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Ets PF00178.17 KFM03298.1 - 3.1e-40 136.1 0.7 6.3e-40 135.2 0.5 1.5 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.11 KFM03298.1 - 6.4e-35 118.7 0.3 1.2e-34 117.8 0.2 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain HSF_DNA-bind PF00447.12 KFM03298.1 - 0.12 12.5 0.0 0.76 9.9 0.0 2.2 2 0 0 2 2 2 0 HSF-type DNA-binding GluR_Homer-bdg PF10606.4 KFM03298.1 - 1.8 8.5 6.2 0.5 10.2 1.6 2.0 2 0 0 2 2 2 0 Homer-binding domain of metabotropic glutamate receptor I-set PF07679.11 KFM03299.1 - 1.7e-42 143.1 0.1 7.4e-12 44.9 0.0 5.7 5 2 0 5 5 5 5 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM03299.1 - 3.9e-39 132.6 0.0 7.4e-09 35.6 0.0 5.4 5 0 0 5 5 5 5 Immunoglobulin domain Ig_3 PF13927.1 KFM03299.1 - 1.8e-26 92.4 2.5 1e-05 25.9 0.0 6.0 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.20 KFM03299.1 - 2.7e-18 65.8 0.6 4.1e-06 26.8 0.0 6.4 5 1 0 5 5 5 5 Immunoglobulin domain V-set PF07686.12 KFM03299.1 - 1.6e-15 57.0 1.8 0.022 14.6 0.0 6.8 4 4 1 5 5 5 4 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM03299.1 - 1.7e-13 50.3 0.1 5.3e-08 32.6 0.0 4.6 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Mid2 PF04478.7 KFM03299.1 - 0.022 14.1 0.1 0.057 12.8 0.1 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Glyco_transf_29 PF00777.13 KFM03301.1 - 1.3e-68 231.0 0.0 1.6e-68 230.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) DcpS_C PF11969.3 KFM03302.1 - 5.3e-29 100.8 0.7 8.7e-29 100.1 0.0 1.6 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 KFM03302.1 - 2e-19 69.9 0.1 3.7e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal CENP-B_N PF04218.8 KFM03302.1 - 0.063 12.7 0.0 0.23 10.9 0.0 1.9 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain TIR_2 PF13676.1 KFM03303.1 - 3e-14 52.9 0.0 4.8e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 TIR domain TIR PF01582.15 KFM03303.1 - 3.2e-12 46.0 0.0 4.6e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 TIR domain PRESAN PF09687.5 KFM03303.1 - 0.096 12.7 0.1 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Plasmodium RESA N-terminal DUF4423 PF14394.1 KFM03303.1 - 0.11 12.0 0.1 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) SIR2_2 PF13289.1 KFM03304.1 - 1.2e-21 77.0 0.1 2.1e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 SIR2-like domain S6PP_C PF08472.5 KFM03304.1 - 0.083 12.5 0.0 0.66 9.5 0.0 2.3 2 0 0 2 2 2 0 Sucrose-6-phosphate phosphohydrolase C-terminal SRP54 PF00448.17 KFM03305.1 - 1.3e-48 165.0 0.4 1.2e-47 161.8 0.3 2.3 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 KFM03305.1 - 1.8e-48 165.3 11.0 2.5e-48 164.8 7.7 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal CbiA PF01656.18 KFM03305.1 - 4.2e-08 32.8 0.1 1.1e-07 31.4 0.1 1.7 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 KFM03305.1 - 1.4e-07 30.6 0.0 2.5e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 ArgK protein SRP54_N PF02881.14 KFM03305.1 - 1.6e-07 31.2 0.1 1.6e-07 31.2 0.0 2.4 3 1 0 3 3 3 1 SRP54-type protein, helical bundle domain MobB PF03205.9 KFM03305.1 - 0.0039 16.8 0.1 0.22 11.2 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 KFM03305.1 - 0.024 14.6 0.0 0.058 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ArsA_ATPase PF02374.10 KFM03305.1 - 0.029 13.4 0.2 0.68 8.9 0.1 2.5 1 1 1 2 2 2 0 Anion-transporting ATPase AAA_22 PF13401.1 KFM03305.1 - 0.037 14.1 0.1 0.34 11.0 0.0 2.5 3 1 0 3 3 3 0 AAA domain PSK_trans_fac PF07704.6 KFM03305.1 - 0.07 13.8 0.3 0.84 10.3 0.1 2.8 3 0 0 3 3 2 0 Rv0623-like transcription factor DUF2151 PF10221.4 KFM03305.1 - 0.21 9.7 5.0 0.32 9.1 3.5 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator ETF PF01012.16 KFM03305.1 - 0.31 10.7 4.0 2 8.1 0.1 2.3 2 0 0 2 2 2 0 Electron transfer flavoprotein domain EI24 PF07264.6 KFM03306.1 - 7.7e-47 159.5 13.8 9.5e-47 159.2 9.5 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF3899 PF13038.1 KFM03306.1 - 0.094 12.8 0.0 0.094 12.8 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3899) STT3 PF02516.9 KFM03307.1 - 3e-146 488.2 45.7 1.4e-141 472.8 27.6 2.0 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.1 KFM03307.1 - 9.6e-07 28.8 16.3 9.6e-07 28.8 11.3 3.5 4 0 0 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase I-set PF07679.11 KFM03308.1 - 6.4e-59 195.7 0.0 7.2e-14 51.4 0.0 6.3 6 1 0 6 6 6 5 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM03308.1 - 4.2e-53 177.3 0.5 2.2e-12 46.9 0.0 5.6 5 0 0 5 5 5 5 Immunoglobulin domain Ig_3 PF13927.1 KFM03308.1 - 2.9e-39 133.3 7.6 2.3e-08 34.3 0.1 6.5 5 1 0 5 5 5 4 Immunoglobulin domain fn3 PF00041.16 KFM03308.1 - 7.1e-39 131.8 4.3 2.9e-16 59.3 0.1 3.9 3 0 0 3 3 3 3 Fibronectin type III domain ig PF00047.20 KFM03308.1 - 1.5e-31 108.2 0.2 5e-06 26.5 0.0 6.1 5 1 0 5 5 5 5 Immunoglobulin domain V-set PF07686.12 KFM03308.1 - 1.2e-29 102.5 2.4 1.5e-06 28.0 0.0 7.9 4 3 0 5 5 5 5 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM03308.1 - 4.5e-08 32.8 0.8 1 9.3 0.0 5.4 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.11 KFM03308.1 - 1.4e-07 30.1 0.0 0.0078 14.5 0.0 4.3 3 1 2 5 5 5 2 Alphaherpesvirus glycoprotein E BiPBP_C PF06832.7 KFM03308.1 - 0.00018 21.3 0.0 0.52 10.2 0.0 4.3 4 0 0 4 4 4 1 Penicillin-Binding Protein C-terminus Family EphA2_TM PF14575.1 KFM03308.1 - 0.071 13.5 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Interfer-bind PF09294.5 KFM03308.1 - 0.078 13.0 0.2 0.96 9.5 0.2 2.3 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III DEAD PF00270.24 KFM03309.1 - 6.2e-28 97.3 0.0 1.2e-27 96.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFM03309.1 - 1.2e-23 82.7 0.2 2.5e-23 81.7 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KFM03309.1 - 0.065 12.9 0.1 0.3 10.8 0.0 2.2 1 1 1 2 2 2 0 Part of AAA domain HYLS1_C PF15311.1 KFM03310.1 - 2.9e-20 72.2 0.6 3.2e-20 72.1 0.4 1.0 1 0 0 1 1 1 1 Hydrolethalus syndrome protein 1 C-terminus PseudoU_synth_1 PF01416.15 KFM03311.1 - 1.6e-33 115.2 0.0 2.8e-20 72.6 0.0 2.6 2 0 0 2 2 2 2 tRNA pseudouridine synthase WD40_alt PF14077.1 KFM03311.1 - 0.015 14.9 2.0 0.015 14.9 1.4 2.6 2 0 0 2 2 2 0 Alternative WD40 repeat motif Tropomyosin_1 PF12718.2 KFM03311.1 - 0.017 14.9 1.9 0.017 14.9 1.3 1.6 2 0 0 2 2 2 0 Tropomyosin like DivIVA PF05103.8 KFM03311.1 - 0.13 12.2 1.0 0.29 11.2 0.7 1.5 1 0 0 1 1 1 0 DivIVA protein PseudoU_synth_2 PF00849.17 KFM03312.1 - 6.4e-30 104.1 0.1 9.9e-30 103.5 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase Innexin PF00876.13 KFM03313.1 - 3.2e-09 36.3 4.2 2.6e-08 33.3 2.9 2.0 1 1 0 1 1 1 1 Innexin IQ PF00612.22 KFM03314.1 - 1.4e-05 24.2 0.5 2.1e-05 23.7 0.3 1.3 1 0 0 1 1 1 1 IQ calmodulin-binding motif I-set PF07679.11 KFM03316.1 - 2.8e-14 52.7 0.0 5.2e-08 32.6 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.12 KFM03316.1 - 2.6e-13 49.8 0.0 1.4e-08 34.6 0.0 3.0 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_3 PF13927.1 KFM03316.1 - 3.1e-11 43.5 0.0 2e-09 37.7 0.0 2.7 2 1 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.1 KFM03316.1 - 5.7e-10 39.1 0.0 4.7e-08 33.0 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.20 KFM03316.1 - 3.9e-07 30.0 0.0 1.4e-05 25.0 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain C2-set_2 PF08205.7 KFM03316.1 - 0.023 14.5 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain MFS_1 PF07690.11 KFM03317.1 - 9.1e-39 133.1 30.9 2.8e-33 115.1 14.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 KFM03317.1 - 0.00099 17.2 4.2 0.026 12.6 0.2 2.9 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Homeobox_KN PF05920.6 KFM03318.1 - 2.2e-19 68.8 1.6 4.4e-19 67.9 1.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KFM03318.1 - 3.8e-08 32.8 0.5 8.7e-08 31.6 0.3 1.6 1 0 0 1 1 1 1 Homeobox domain RNA_pol_3_Rpc31 PF11705.3 KFM03318.1 - 0.0035 17.3 7.1 0.0062 16.5 4.9 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 TFIIA PF03153.8 KFM03318.1 - 0.017 15.0 3.9 0.029 14.2 2.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BSP_II PF05432.6 KFM03318.1 - 0.027 13.7 9.2 0.042 13.1 6.4 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Myc_N PF01056.13 KFM03318.1 - 0.063 12.4 4.7 0.14 11.3 3.3 1.5 1 0 0 1 1 1 0 Myc amino-terminal region TT_ORF2 PF02957.10 KFM03318.1 - 0.62 10.7 5.4 1.5 9.5 3.7 1.7 1 0 0 1 1 1 0 TT viral ORF2 NOA36 PF06524.7 KFM03318.1 - 0.9 8.7 5.3 0.13 11.4 0.9 1.5 2 0 0 2 2 2 0 NOA36 protein Daxx PF03344.10 KFM03318.1 - 2.4 6.5 10.8 3.4 6.0 7.5 1.2 1 0 0 1 1 1 0 Daxx Family TRAP_alpha PF03896.11 KFM03318.1 - 2.5 7.0 9.4 4.2 6.2 6.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.7 KFM03318.1 - 3.2 5.5 10.2 4.5 5.0 7.1 1.1 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 KFM03318.1 - 9.1 5.7 15.9 16 4.9 11.0 1.3 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 KFM03318.1 - 9.9 6.4 16.1 20 5.4 11.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FEZ PF07763.8 KFM03319.1 - 6.8e-36 124.1 1.1 1.1e-35 123.5 0.8 1.4 1 0 0 1 1 1 1 FEZ-like protein TT_ORF2 PF02957.10 KFM03319.1 - 0.028 15.1 2.6 0.028 15.1 1.8 2.0 3 0 0 3 3 3 0 TT viral ORF2 Nop14 PF04147.7 KFM03319.1 - 1.2 6.9 8.0 1.4 6.7 5.5 1.1 1 0 0 1 1 1 0 Nop14-like family Nop53 PF07767.6 KFM03319.1 - 3.6 6.4 11.3 6.4 5.6 7.8 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) 7tm_4 PF13853.1 KFM03320.1 - 3.4e-40 137.1 15.4 3.4e-40 137.1 10.6 2.1 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFM03320.1 - 4.5e-26 91.5 22.5 5.9e-26 91.1 15.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) zf-tcix PF14952.1 KFM03321.1 - 1.3e-20 72.4 7.2 3.2e-20 71.1 5.0 1.7 1 0 0 1 1 1 1 Putative treble-clef, zinc-finger, Zn-binding Mu-like_Com PF10122.4 KFM03321.1 - 0.034 13.1 2.5 0.11 11.6 1.7 1.8 1 0 0 1 1 1 0 Mu-like prophage protein Com RRM_1 PF00076.17 KFM03322.1 - 2.6e-66 219.1 0.0 2.5e-23 81.4 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM03322.1 - 7e-36 122.0 0.0 9.5e-15 54.3 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM03322.1 - 3.1e-31 107.0 0.3 7.2e-10 38.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 KFM03322.1 - 1.5e-06 27.8 0.0 0.003 17.1 0.0 3.0 3 0 0 3 3 3 2 Calcipressin Nup35_RRM_2 PF14605.1 KFM03322.1 - 9.6e-06 25.2 0.6 0.0075 16.0 0.0 3.4 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KFM03322.1 - 6e-05 22.8 0.0 0.34 10.7 0.0 3.1 2 1 1 3 3 3 2 RNA binding motif Nup35_RRM PF05172.8 KFM03322.1 - 0.0016 18.1 0.2 0.098 12.4 0.1 3.1 1 1 1 2 2 2 1 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.6 KFM03322.1 - 0.031 14.2 0.1 5.1 7.1 0.0 2.8 2 0 0 2 2 2 0 RNA binding domain DbpA PF03880.10 KFM03322.1 - 0.065 12.8 0.0 6.6 6.4 0.0 3.1 3 0 0 3 3 3 0 DbpA RNA binding domain HATPase_c PF02518.21 KFM03322.1 - 0.12 12.1 0.1 0.27 10.9 0.0 1.6 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LSM PF01423.17 KFM03323.1 - 2.8e-18 65.2 0.2 3.1e-18 65.0 0.1 1.0 1 0 0 1 1 1 1 LSM domain LRR_8 PF13855.1 KFM03324.1 - 9.7e-56 185.3 42.8 1.4e-14 53.5 1.2 5.2 2 2 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 KFM03324.1 - 4.2e-30 102.8 36.8 1e-07 31.3 3.4 6.5 3 2 5 8 8 8 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM03324.1 - 1e-21 73.5 34.7 0.01 15.7 0.3 11.1 11 0 0 11 11 11 9 Leucine Rich Repeat LRR_5 PF13306.1 KFM03324.1 - 1.6e-20 73.1 1.5 2e-09 37.2 0.0 2.5 1 1 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_7 PF13504.1 KFM03324.1 - 1.3e-10 39.6 33.3 0.37 11.1 0.2 9.9 10 0 0 10 10 10 5 Leucine rich repeat LRR_6 PF13516.1 KFM03324.1 - 7e-09 34.8 32.0 0.47 10.6 0.4 9.2 9 1 0 9 9 9 3 Leucine Rich repeat LRR_9 PF14580.1 KFM03324.1 - 1.5e-07 31.1 1.0 0.0042 16.6 0.2 2.8 1 1 2 3 3 3 2 Leucine-rich repeat LRRNT PF01462.13 KFM03324.1 - 0.025 14.0 3.4 0.051 13.0 1.3 2.3 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain Viral_env_E26 PF11050.3 KFM03324.1 - 0.095 11.8 1.2 0.46 9.6 0.6 2.2 2 0 0 2 2 2 0 Virus envelope protein E26 DUF3481 PF11980.3 KFM03324.1 - 0.098 12.4 1.5 0.1 12.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3481) 7tm_1 PF00001.16 KFM03325.1 - 1.5e-83 279.8 7.3 2.3e-83 279.2 5.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM03325.1 - 1.1e-17 64.1 5.4 1.5e-17 63.6 3.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 KFM03325.1 - 4.3e-07 29.3 0.1 7.2e-07 28.6 0.1 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.4 KFM03325.1 - 2.7e-06 26.7 7.2 5.4e-06 25.7 5.0 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Amidohydro_1 PF01979.15 KFM03326.1 - 1.7e-45 156.1 0.0 2.1e-45 155.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KFM03326.1 - 1e-11 45.4 0.0 1.6e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KFM03326.1 - 1.9e-09 37.1 2.7 2.4e-09 36.8 0.4 2.3 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 KFM03326.1 - 1.2e-05 24.7 0.9 0.0002 20.6 0.0 2.5 2 1 0 2 2 2 1 Amidohydrolase family BNIP3 PF06553.7 KFM03327.1 - 2.6e-79 265.1 1.9 2.9e-79 265.0 1.4 1.0 1 0 0 1 1 1 1 BNIP3 WD40 PF00400.27 KFM03328.1 - 7e-15 54.2 1.8 0.81 9.6 0.0 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Y_phosphatase2 PF03162.8 KFM03328.1 - 0.038 13.3 0.5 1.1 8.6 0.0 2.5 2 0 0 2 2 2 0 Tyrosine phosphatase family TIG PF01833.19 KFM03329.1 - 5.3e-13 48.7 0.1 2.2e-12 46.7 0.0 2.2 1 0 0 1 1 1 1 IPT/TIG domain PP1_bind PF15276.1 KFM03330.1 - 1.1e-19 70.1 0.8 1.4e-19 69.8 0.5 1.2 1 0 0 1 1 1 1 Protein phosphatase 1 binding Pentapeptide PF00805.17 KFM03331.1 - 3.5e-40 134.6 29.9 3.9e-13 48.3 1.0 4.8 2 2 3 5 5 5 5 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 KFM03331.1 - 6.7e-22 77.0 1.8 1.6e-11 43.8 0.0 3.2 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) BTB_2 PF02214.17 KFM03331.1 - 3e-20 72.2 0.0 4.9e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Pentapeptide_3 PF13576.1 KFM03331.1 - 5.5e-15 54.9 0.0 1.3e-05 24.9 0.0 4.6 1 1 1 3 3 3 3 Pentapeptide repeats (9 copies) DUF3354 PF11834.3 KFM03331.1 - 1e-14 53.8 0.1 1.7e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3354) BTB PF00651.26 KFM03331.1 - 3.4e-05 23.7 0.0 7.5e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain GnRH PF00446.12 KFM03332.1 - 0.0022 17.9 5.3 0.0022 17.9 3.7 1.6 2 0 0 2 2 2 1 Gonadotropin-releasing hormone Filament PF00038.16 KFM03333.1 - 2.5e-100 335.9 45.3 2.5e-100 335.9 31.4 2.2 2 0 0 2 2 2 1 Intermediate filament protein Filament_head PF04732.9 KFM03333.1 - 6.1e-08 33.2 20.5 9.3e-07 29.4 7.7 2.5 2 0 0 2 2 2 2 Intermediate filament head (DNA binding) region Bacillus_HBL PF05791.6 KFM03333.1 - 0.00097 18.5 6.0 0.00097 18.5 4.1 2.3 2 2 0 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) TPR_MLP1_2 PF07926.7 KFM03333.1 - 0.0025 17.5 14.4 0.0025 17.5 10.0 5.8 3 2 2 5 5 5 2 TPR/MLP1/MLP2-like protein DUF1664 PF07889.7 KFM03333.1 - 0.0061 16.3 1.8 0.0061 16.3 1.2 4.2 3 2 2 5 5 5 1 Protein of unknown function (DUF1664) Vps23_core PF09454.5 KFM03333.1 - 0.053 13.1 0.4 0.053 13.1 0.3 2.6 3 0 0 3 3 3 0 Vps23 core domain ACCA PF03255.9 KFM03333.1 - 9.5 5.7 13.3 2.8 7.4 1.2 3.4 2 1 1 4 4 4 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Filament PF00038.16 KFM03334.1 - 7.3e-107 357.4 45.5 7.3e-107 357.4 31.5 2.2 2 0 0 2 2 2 1 Intermediate filament protein Filament_head PF04732.9 KFM03334.1 - 0.0096 16.6 2.3 0.038 14.6 0.2 2.6 3 0 0 3 3 3 1 Intermediate filament head (DNA binding) region NPV_P10 PF05531.7 KFM03334.1 - 0.049 13.8 1.1 0.049 13.8 0.8 4.1 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 KFM03334.1 - 0.75 8.9 9.0 4 6.5 1.8 3.1 1 1 3 4 4 4 0 Reovirus sigma C capsid protein DUF948 PF06103.6 KFM03334.1 - 1.9 8.4 8.0 58 3.6 0.1 4.4 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.7 KFM03334.1 - 3.6 7.3 15.9 4.2 7.2 0.8 4.1 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 KFM03334.1 - 7.7 6.3 24.9 0.097 12.4 0.6 4.5 4 1 1 5 5 5 0 Protein of unknown function (DUF1664) Reprolysin PF01421.14 KFM03335.1 - 2.7e-33 115.2 3.6 2.7e-33 115.2 2.5 2.4 3 0 0 3 3 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.7 KFM03335.1 - 2.7e-26 91.8 12.1 2.7e-26 91.8 8.4 3.9 4 2 0 4 4 2 1 ADAM cysteine-rich Disintegrin PF00200.18 KFM03335.1 - 2.4e-23 82.1 30.0 2.4e-23 82.1 20.8 4.7 4 2 0 4 4 2 1 Disintegrin Reprolysin_2 PF13574.1 KFM03335.1 - 1.4e-10 41.5 1.1 2.5e-10 40.6 0.8 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFM03335.1 - 9.2e-09 35.1 0.7 1.7e-08 34.2 0.5 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KFM03335.1 - 2.4e-08 34.5 0.2 2.4e-08 34.5 0.2 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KFM03335.1 - 4.8e-07 29.9 0.9 4.8e-07 29.9 0.6 2.1 2 0 0 2 2 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.19 KFM03335.1 - 0.0049 16.6 0.0 0.0078 15.9 0.0 1.2 1 0 0 1 1 1 1 Matrixin EGF_2 PF07974.8 KFM03335.1 - 0.0082 16.2 8.8 0.0082 16.2 6.1 6.9 5 2 1 6 6 5 1 EGF-like domain Peptidase_M43 PF05572.8 KFM03335.1 - 0.023 14.2 0.1 0.061 12.9 0.0 1.7 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A DUF3810 PF12725.2 KFM03335.1 - 0.027 13.3 0.2 0.037 12.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Peptidase_M66 PF10462.4 KFM03335.1 - 0.05 12.4 0.1 0.079 11.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase M66 WLM PF08325.5 KFM03335.1 - 0.08 12.8 0.8 0.15 11.9 0.5 1.3 1 0 0 1 1 1 0 WLM domain Peptidase_M48 PF01435.13 KFM03335.1 - 0.09 12.3 0.1 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M48 Stanniocalcin PF03298.8 KFM03336.1 - 2.9e-102 340.0 5.4 3.5e-102 339.8 3.8 1.0 1 0 0 1 1 1 1 Stanniocalcin family CD45 PF12567.3 KFM03336.1 - 0.16 11.7 4.6 8.5 6.3 0.0 3.4 3 1 0 3 3 3 0 Leukocyte receptor CD45 Homeobox PF00046.24 KFM03337.1 - 1.4e-21 75.8 4.8 2.4e-21 75.0 3.4 1.4 1 0 0 1 1 1 1 Homeobox domain Mito_carr PF00153.22 KFM03338.1 - 2.8e-57 190.4 4.7 9.6e-21 73.3 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 KFM03338.1 - 0.26 11.1 1.6 0.76 9.6 0.2 2.4 3 0 0 3 3 3 0 UcrQ family GDA1_CD39 PF01150.12 KFM03339.1 - 2.6e-91 306.3 0.0 3.4e-91 305.9 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family R3H PF01424.17 KFM03340.1 - 1.4e-13 50.3 0.2 2.7e-13 49.3 0.1 1.5 1 0 0 1 1 1 1 R3H domain DUF2414 PF10309.4 KFM03340.1 - 0.00043 19.8 0.0 0.00082 19.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) 7tm_1 PF00001.16 KFM03341.1 - 6.2e-82 274.6 12.7 7.9e-82 274.2 8.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM03341.1 - 4.6e-10 39.0 12.1 4.4e-09 35.8 8.4 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM03341.1 - 9.6e-10 38.0 8.3 9.6e-10 38.0 5.8 2.5 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF3390 PF11870.3 KFM03341.1 - 0.039 13.8 0.3 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3390) CAAD PF14159.1 KFM03341.1 - 0.18 11.4 2.3 0.31 10.7 0.0 2.6 3 0 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Snf7 PF03357.16 KFM03342.1 - 3.5e-24 85.0 6.5 3.5e-24 85.0 4.5 2.2 1 1 1 2 2 2 1 Snf7 PspA_IM30 PF04012.7 KFM03342.1 - 5.8e-06 25.8 0.4 5.8e-06 25.8 0.3 2.3 2 0 0 2 2 2 1 PspA/IM30 family Snapin_Pallidin PF14712.1 KFM03342.1 - 0.0034 17.6 9.4 0.072 13.4 1.4 3.6 3 1 0 3 3 3 1 Snapin/Pallidin DUF342 PF03961.8 KFM03342.1 - 0.22 9.8 4.3 0.17 10.2 1.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) DUF2951 PF11166.3 KFM03342.1 - 1.9 8.4 7.5 4.5 7.1 0.1 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF2951) Death PF00531.17 KFM03343.1 - 1.1e-16 60.3 0.0 1.8e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Death domain TNFR_c6 PF00020.13 KFM03343.1 - 5.2e-08 32.8 42.1 1e-06 28.7 5.6 3.7 3 0 0 3 3 3 2 TNFR/NGFR cysteine-rich region Endomucin PF07010.7 KFM03343.1 - 0.071 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Endomucin DUF4448 PF14610.1 KFM03343.1 - 0.1 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) zf-Di19 PF05605.7 KFM03344.1 - 4.8e-18 65.0 15.4 1.3e-17 63.6 2.3 2.8 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding Rubredoxin PF00301.15 KFM03344.1 - 0.00044 20.0 2.9 2.8 7.9 0.0 3.5 3 0 0 3 3 3 1 Rubredoxin UIM PF02809.15 KFM03344.1 - 0.0025 17.2 3.8 0.0043 16.5 2.7 1.4 1 0 0 1 1 1 1 Ubiquitin interaction motif PhnA_Zn_Ribbon PF08274.7 KFM03344.1 - 0.0067 16.1 0.2 3.2 7.6 0.0 3.8 3 1 0 3 3 3 1 PhnA Zinc-Ribbon DUF4187 PF13821.1 KFM03344.1 - 0.087 12.4 0.2 0.27 10.8 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) zinc_ribbon_2 PF13240.1 KFM03344.1 - 0.11 12.0 0.1 0.11 12.0 0.0 4.1 4 0 0 4 4 4 0 zinc-ribbon domain zf-BED PF02892.10 KFM03344.1 - 0.22 11.3 8.0 0.51 10.1 0.3 3.4 3 1 0 3 3 3 0 BED zinc finger zf-C2H2_4 PF13894.1 KFM03344.1 - 0.24 11.8 14.7 1.5 9.3 0.5 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger zf-ribbon_3 PF13248.1 KFM03344.1 - 0.29 10.3 0.0 0.29 10.3 0.0 4.4 5 0 0 5 5 4 0 zinc-ribbon domain zf-DNA_Pol PF08996.5 KFM03344.1 - 0.5 9.6 6.2 4.7 6.5 1.0 2.1 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger Cmc1 PF08583.5 KFM03344.1 - 0.88 9.3 5.3 12 5.7 0.5 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like zf-H2C2_2 PF13465.1 KFM03344.1 - 1.1 9.6 14.6 2.7 8.4 0.5 4.6 4 0 0 4 4 4 0 Zinc-finger double domain Prok-RING_1 PF14446.1 KFM03344.1 - 1.9 8.3 14.3 7.1 6.4 0.6 4.4 3 2 1 4 4 4 0 Prokaryotic RING finger family 1 zf-C4pol PF14260.1 KFM03344.1 - 2.9 7.9 13.7 0.8 9.7 3.6 2.8 2 2 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Prok-RING_4 PF14447.1 KFM03344.1 - 3.7 7.1 7.4 4 7.0 0.3 3.5 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-P11 PF03854.9 KFM03344.1 - 4.3 6.8 10.3 1.1 8.8 3.7 2.5 2 0 0 2 2 2 0 P-11 zinc finger Elf1 PF05129.8 KFM03344.1 - 6.4 6.5 8.5 1.1 9.0 0.4 2.6 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like DZR PF12773.2 KFM03344.1 - 7.2 6.5 23.1 1.5e+04 -6.6 16.0 3.6 1 1 0 1 1 0 0 Double zinc ribbon DUF4451 PF14616.1 KFM03344.1 - 7.3 6.3 11.1 1.9 8.2 1.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4451) CDT1 PF08839.6 KFM03345.1 - 5.6e-60 201.9 0.1 7.5e-60 201.5 0.1 1.2 1 0 0 1 1 1 1 DNA replication factor CDT1 like Pribosyltran PF00156.22 KFM03346.1 - 1.4e-21 76.4 0.0 1.7e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KFM03346.1 - 0.0066 15.6 0.0 0.009 15.2 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 KFM03346.1 - 0.053 12.8 0.0 0.069 12.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase Sulfatase PF00884.18 KFM03347.1 - 1.6e-79 267.3 0.0 2.1e-79 266.8 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 KFM03347.1 - 1.1e-36 125.9 0.0 1.9e-36 125.2 0.0 1.3 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.17 KFM03347.1 - 1.4e-09 37.8 0.0 6.2e-09 35.6 0.0 1.8 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KFM03347.1 - 0.0051 15.3 0.0 0.0065 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sedlin_N PF04628.8 KFM03348.1 - 4.5e-36 123.6 0.5 5.1e-36 123.4 0.4 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 KFM03348.1 - 1.9e-10 40.6 0.2 2.3e-10 40.3 0.2 1.1 1 0 0 1 1 1 1 Sybindin-like family RRM_1 PF00076.17 KFM03349.1 - 9.5e-18 63.6 0.0 1.5e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM03349.1 - 4.5e-14 52.1 0.0 6.4e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM03349.1 - 2e-08 33.9 0.0 3.1e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFM03349.1 - 0.14 11.9 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif GRP PF07172.6 KFM03349.1 - 0.18 12.2 3.3 0.27 11.7 1.0 2.0 2 0 0 2 2 2 0 Glycine rich protein family AMP-binding PF00501.23 KFM03350.1 - 1.2e-82 277.6 0.2 1.7e-82 277.0 0.1 1.3 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFM03350.1 - 2.2e-13 50.9 0.2 6e-13 49.5 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain YcbB PF08664.5 KFM03351.1 - 0.061 13.1 4.1 0.069 12.9 0.9 2.3 2 0 0 2 2 2 0 YcbB domain Ank PF00023.25 KFM03352.1 - 5.4e-24 82.7 0.2 6.4e-07 28.8 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 KFM03352.1 - 6e-24 84.2 0.3 2.4e-13 50.2 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFM03352.1 - 1.4e-19 69.6 0.4 2.7e-09 36.9 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFM03352.1 - 1.4e-15 57.2 0.9 1.9e-09 37.7 0.1 3.3 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM03352.1 - 7e-14 50.5 0.2 0.00055 19.9 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat Peptidase_M41 PF01434.13 KFM03353.1 - 7.3e-70 234.7 0.1 1.1e-69 234.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KFM03353.1 - 3e-39 134.2 0.0 1e-38 132.4 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 KFM03353.1 - 2.1e-08 34.2 0.0 4.9e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.9 KFM03353.1 - 1.3e-06 28.1 0.3 1.8e-05 24.5 0.0 2.8 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KFM03353.1 - 0.00019 21.4 0.2 0.0027 17.7 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KFM03353.1 - 0.00022 21.3 0.1 0.027 14.5 0.0 3.3 3 1 0 3 3 3 1 AAA domain AAA_2 PF07724.9 KFM03353.1 - 0.00027 20.8 0.0 0.0011 18.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KFM03353.1 - 0.0014 17.7 0.0 0.0048 15.9 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KFM03353.1 - 0.0026 18.5 0.0 0.014 16.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 KFM03353.1 - 0.0033 16.2 0.1 0.0057 15.4 0.1 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 KFM03353.1 - 0.0062 16.2 0.3 0.028 14.1 0.1 2.2 2 0 0 2 2 2 1 Part of AAA domain IstB_IS21 PF01695.12 KFM03353.1 - 0.007 15.8 0.1 0.016 14.6 0.1 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 KFM03353.1 - 0.016 14.3 0.1 0.03 13.4 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 KFM03353.1 - 0.021 14.7 0.5 0.045 13.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.1 KFM03353.1 - 0.025 14.4 0.0 0.061 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KFM03353.1 - 0.066 13.0 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KFM03353.1 - 0.088 11.8 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.7 KFM03353.1 - 0.095 12.3 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Peptidase_M50B PF13398.1 KFM03353.1 - 0.14 11.5 1.4 0.25 10.6 0.0 2.0 2 0 0 2 2 2 0 Peptidase M50B-like Ribosomal_L13e PF01294.13 KFM03354.1 - 6.9e-93 309.0 7.6 8.9e-93 308.7 5.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Sulfotransfer_1 PF00685.22 KFM03355.1 - 8.2e-08 31.8 0.2 1.5e-07 30.9 0.1 1.3 1 1 0 1 1 1 1 Sulfotransferase domain Snf7 PF03357.16 KFM03356.1 - 5.1e-16 58.5 10.3 6.7e-16 58.1 7.2 1.1 1 0 0 1 1 1 1 Snf7 FliG_N PF14842.1 KFM03356.1 - 0.024 14.7 1.1 0.05 13.7 0.8 1.6 1 1 0 1 1 1 0 FliG N-terminal domain Spore_YpjB PF09577.5 KFM03356.1 - 0.027 14.0 2.6 0.057 12.9 1.9 1.4 1 1 1 2 2 2 0 Sporulation protein YpjB (SpoYpjB) DUF724 PF05266.9 KFM03356.1 - 0.031 13.9 1.1 0.038 13.5 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) GrpE PF01025.14 KFM03356.1 - 0.056 12.9 1.1 0.077 12.5 0.5 1.5 1 1 0 1 1 1 0 GrpE Wbp11 PF09429.5 KFM03356.1 - 0.056 13.4 0.5 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 WW domain binding protein 11 Baculo_PEP_C PF04513.7 KFM03356.1 - 0.069 12.9 4.4 0.12 12.2 1.9 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cytochrom_B562 PF07361.6 KFM03356.1 - 0.41 11.0 4.8 0.88 10.0 3.3 1.6 1 1 0 1 1 1 0 Cytochrome b562 FUN14 PF04930.10 KFM03356.1 - 0.53 10.5 3.1 9.3 6.5 2.2 2.4 1 1 0 1 1 1 0 FUN14 family Pkinase PF00069.20 KFM03357.1 - 1e-63 214.9 0.0 1.2e-63 214.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM03357.1 - 6.6e-35 120.4 0.0 7.9e-35 120.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM03357.1 - 1.1e-09 37.6 0.0 3.1e-06 26.3 0.0 2.1 1 1 1 2 2 2 2 Kinase-like RIO1 PF01163.17 KFM03357.1 - 0.00089 18.6 0.3 0.0014 17.9 0.2 1.3 1 1 0 1 1 1 1 RIO1 family Herpes_IE1 PF07340.6 KFM03357.1 - 0.01 14.3 0.1 0.014 13.8 0.0 1.1 1 0 0 1 1 1 0 Cytomegalovirus IE1 protein Seadorna_VP7 PF07387.6 KFM03357.1 - 0.031 13.0 0.0 0.049 12.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 KFM03357.1 - 0.035 13.1 0.0 0.13 11.2 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFM03357.1 - 0.062 13.0 0.0 0.24 11.0 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf-C2H2_4 PF13894.1 KFM03358.1 - 1.9e-14 52.8 37.0 0.0027 17.9 0.8 6.5 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2 PF00096.21 KFM03358.1 - 4.1e-14 51.9 42.2 0.00011 22.2 1.6 6.5 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM03358.1 - 5.9e-12 45.2 43.0 0.0002 21.4 0.1 7.1 7 0 0 7 7 7 4 Zinc-finger double domain zf-AD PF07776.10 KFM03358.1 - 8e-05 22.5 0.1 8e-05 22.5 0.1 3.6 3 0 0 3 3 3 1 Zinc-finger associated domain (zf-AD) IBR PF01485.16 KFM03358.1 - 0.12 12.2 22.2 4.2 7.3 0.3 5.1 2 1 1 3 3 3 0 IBR domain Zn-ribbon_8 PF09723.5 KFM03358.1 - 0.2 11.6 22.8 0.23 11.4 0.0 4.7 4 1 0 4 4 4 0 Zinc ribbon domain DUF2197 PF09963.4 KFM03358.1 - 0.37 10.7 8.0 0.46 10.4 0.4 3.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2197) ADK_lid PF05191.9 KFM03358.1 - 0.85 9.3 13.8 0.47 10.1 0.1 4.5 5 0 0 5 5 5 0 Adenylate kinase, active site lid zf-C2H2_6 PF13912.1 KFM03358.1 - 3.3 7.7 20.6 1.9 8.4 0.4 4.7 5 0 0 5 5 5 0 C2H2-type zinc finger Fanconi_A PF03511.9 KFM03359.1 - 6.7e-10 38.6 0.2 6.2e-09 35.5 0.1 2.6 2 0 0 2 2 2 1 Fanconi anaemia group A protein Tcf25 PF04910.9 KFM03360.1 - 5.5e-110 367.6 3.3 7.8e-110 367.2 2.3 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 SPT6_acidic PF14632.1 KFM03360.1 - 1.2 9.3 11.0 3.4 7.9 7.6 1.8 1 0 0 1 1 1 0 Acidic N-terminal SPT6 7tm_1 PF00001.16 KFM03362.1 - 6e-42 143.5 35.4 8.4e-40 136.5 24.5 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM03362.1 - 3.7e-06 26.2 31.2 2e-05 23.9 21.6 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx EVC2_like PF12297.3 KFM03362.1 - 0.062 11.9 3.6 0.092 11.3 2.5 1.2 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein DUF809 PF05663.6 KFM03362.1 - 0.54 10.1 3.9 0.71 9.7 1.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF809) 7TM_GPCR_Srx PF10328.4 KFM03362.1 - 3.2 6.7 36.2 0.015 14.4 13.6 2.5 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Tubulin_C PF03953.12 KFM03363.1 - 3.3e-48 162.9 0.0 5.6e-48 162.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.20 KFM03363.1 - 3.5e-43 147.9 0.0 5.6e-43 147.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.1 KFM03363.1 - 0.012 15.0 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Tubulin domain RHS PF03527.9 KFM03364.1 - 1.3 8.8 3.8 1.2 8.9 0.3 2.2 2 0 0 2 2 2 0 RHS protein Kinesin PF00225.18 KFM03365.1 - 8.6e-32 110.1 0.0 8.6e-32 110.1 0.0 2.7 3 0 0 3 3 3 1 Kinesin motor domain Reo_sigmaC PF04582.7 KFM03365.1 - 1.8 7.6 26.3 0.063 12.4 2.2 4.2 1 1 2 4 4 4 0 Reovirus sigma C capsid protein IncA PF04156.9 KFM03365.1 - 8.5 5.9 114.0 0.028 14.0 19.4 5.2 4 1 1 5 5 5 0 IncA protein DUF2246 PF10229.4 KFM03368.1 - 5.6e-128 426.0 0.0 6.3e-128 425.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2246) DUF4085 PF13315.1 KFM03368.1 - 0.014 14.7 0.5 0.02 14.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) Ras PF00071.17 KFM03369.1 - 2.8e-21 75.5 0.0 3.5e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM03369.1 - 0.0053 17.2 0.0 0.01 16.3 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein NID PF07292.8 KFM03370.1 - 2e-10 40.5 0.0 6e-05 23.0 0.0 2.5 2 0 0 2 2 2 2 Nmi/IFP 35 domain (NID) RRM_1 PF00076.17 KFM03370.1 - 0.0004 19.9 0.0 0.00092 18.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM03370.1 - 0.00053 19.9 0.1 0.0017 18.2 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3391 PF11871.3 KFM03370.1 - 0.13 12.4 0.7 0.28 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF2064 PF09837.4 KFM03370.1 - 0.15 11.7 0.0 1.3 8.6 0.0 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2064) NID PF07292.8 KFM03371.1 - 2.8e-37 126.6 0.1 1.4e-27 95.5 0.0 2.1 2 0 0 2 2 2 2 Nmi/IFP 35 domain (NID) RRM_6 PF14259.1 KFM03371.1 - 5.4e-07 29.4 0.0 0.015 15.2 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM03371.1 - 0.00074 19.3 0.7 0.48 10.3 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF237 PF03072.9 KFM03371.1 - 0.034 14.0 0.0 0.062 13.2 0.0 1.5 1 0 0 1 1 1 0 MG032/MG096/MG288 family 1 Nup35_RRM_2 PF14605.1 KFM03371.1 - 0.036 13.8 0.0 25 4.7 0.0 3.2 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.17 KFM03371.1 - 0.078 12.6 0.2 5.5 6.7 0.0 2.9 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CUB PF00431.15 KFM03372.1 - 2.9e-36 123.8 0.1 5.4e-36 123.0 0.1 1.4 1 0 0 1 1 1 1 CUB domain Xlink PF00193.12 KFM03372.1 - 1.2e-32 111.8 1.7 2.1e-32 111.0 1.2 1.4 1 0 0 1 1 1 1 Extracellular link domain Rif1_N PF12231.3 KFM03373.1 - 1.5e-84 284.1 7.5 3.5e-84 282.9 5.2 1.6 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Arf PF00025.16 KFM03374.1 - 1.6e-64 216.3 0.9 1.8e-64 216.2 0.6 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KFM03374.1 - 2.8e-14 52.8 0.4 3.1e-14 52.7 0.3 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KFM03374.1 - 2.9e-12 46.1 0.3 3.5e-12 45.9 0.2 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KFM03374.1 - 3.4e-11 43.6 0.1 4.5e-11 43.2 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 KFM03374.1 - 3.5e-08 32.5 1.0 1.1e-05 24.2 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 KFM03374.1 - 1.1e-07 31.8 0.2 1.4e-07 31.4 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFM03374.1 - 1.7e-07 30.6 0.4 2.1e-07 30.3 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFM03374.1 - 0.00013 21.4 0.3 0.00092 18.6 0.2 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.1 KFM03374.1 - 0.0062 16.4 0.2 0.034 14.0 0.2 2.0 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 KFM03374.1 - 0.052 12.8 0.9 0.25 10.6 0.6 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B Octopine_DH PF02317.12 KFM03374.1 - 0.055 13.1 0.1 0.075 12.6 0.1 1.4 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain VHS PF00790.14 KFM03375.1 - 1.7e-38 131.4 1.2 1.8e-37 128.1 0.0 2.3 2 0 0 2 2 2 1 VHS domain SH3_1 PF00018.23 KFM03375.1 - 8.7e-19 66.6 0.1 1.7e-18 65.7 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFM03375.1 - 7.7e-14 51.0 0.1 1.4e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFM03375.1 - 8.2e-12 44.4 0.0 1.6e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.15 KFM03375.1 - 4.4e-05 22.7 0.8 0.0001 21.5 0.5 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif ZapA PF05164.8 KFM03375.1 - 0.02 14.8 0.0 0.093 12.7 0.0 2.1 2 0 0 2 2 2 0 Cell division protein ZapA FH2 PF02181.18 KFM03376.1 - 4.5e-100 335.1 11.1 4.5e-100 335.1 7.7 3.7 5 0 0 5 5 5 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 KFM03376.1 - 6.9e-52 175.7 16.1 6.9e-52 175.7 11.2 2.9 3 0 0 3 3 3 1 Diaphanous FH3 Domain Drf_GBD PF06371.8 KFM03376.1 - 2.3e-22 79.2 3.5 2.6e-13 49.7 0.4 5.3 4 1 0 4 4 4 2 Diaphanous GTPase-binding Domain DoxX PF07681.7 KFM03376.1 - 0.19 12.1 2.0 0.66 10.4 0.4 2.3 2 0 0 2 2 2 0 DoxX Reo_sigmaC PF04582.7 KFM03376.1 - 1.9 7.5 5.0 0.32 10.1 0.7 1.6 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 KFM03376.1 - 3.5 7.4 17.6 0.57 9.9 7.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Endonuc_Holl PF10107.4 KFM03376.1 - 5.1 6.7 16.2 0.98 9.0 2.6 2.8 2 1 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase COG2 PF06148.6 KFM03376.1 - 9.7 6.0 19.8 0.014 15.3 4.8 2.9 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Glycos_transf_2 PF00535.21 KFM03377.1 - 1.3e-32 112.7 0.0 2.4e-32 111.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 KFM03377.1 - 3.9e-29 101.2 1.0 6.3e-29 100.5 0.7 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.1 KFM03377.1 - 8.3e-11 42.1 0.0 1.3e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 KFM03377.1 - 2.2e-07 30.2 0.1 4.8e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFM03377.1 - 3.2e-07 29.7 0.0 2.5e-06 26.8 0.0 2.3 2 1 0 2 2 2 1 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.1 KFM03377.1 - 0.00014 22.2 0.0 0.52 10.7 0.0 2.6 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like IRK PF01007.15 KFM03378.1 - 5.8e-158 525.0 0.0 6.5e-158 524.8 0.0 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel DUF3311 PF11755.3 KFM03378.1 - 0.0082 15.6 2.1 0.016 14.7 1.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3311) Ion_trans_2 PF07885.11 KFM03378.1 - 0.21 11.3 10.8 1 9.0 7.5 2.1 1 1 0 1 1 1 0 Ion channel DAO PF01266.19 KFM03379.1 - 5.6e-50 170.2 0.0 7.4e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase EF-hand_7 PF13499.1 KFM03379.1 - 2.2e-11 43.7 0.6 5.9e-11 42.3 0.4 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KFM03379.1 - 3.6e-10 38.3 0.6 0.00021 20.3 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KFM03379.1 - 2.2e-09 36.3 0.2 8.7e-05 22.0 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain FAD_oxidored PF12831.2 KFM03379.1 - 2.8e-08 33.2 0.1 4e-07 29.4 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFM03379.1 - 1.1e-07 31.1 0.1 1.3e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 KFM03379.1 - 2.7e-06 26.5 0.0 0.00061 18.7 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 KFM03379.1 - 2.5e-05 24.2 0.1 0.0014 18.5 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_8 PF13833.1 KFM03379.1 - 0.00012 21.6 0.4 0.00051 19.6 0.1 2.2 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 KFM03379.1 - 0.00025 20.2 0.7 0.56 9.6 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.1 KFM03379.1 - 0.00055 19.7 0.0 0.0014 18.4 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain HI0933_like PF03486.9 KFM03379.1 - 0.0025 16.3 0.0 0.004 15.6 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 KFM03379.1 - 0.0029 17.5 0.2 0.012 15.5 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KFM03379.1 - 0.015 14.4 0.0 0.038 13.0 0.0 1.7 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 KFM03379.1 - 0.017 15.5 0.2 0.14 12.5 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KFM03379.1 - 0.064 12.2 0.1 0.38 9.7 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Agouti PF05039.7 KFM03380.1 - 1.6 9.1 7.3 0.17 12.2 1.8 1.8 2 1 0 2 2 2 0 Agouti protein PDZ PF00595.19 KFM03381.1 - 5e-11 42.6 0.0 1.1e-10 41.5 0.0 1.6 1 1 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM03381.1 - 0.003 17.4 0.0 0.0052 16.6 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Rnf-Nqr PF02508.9 KFM03381.1 - 0.075 12.6 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Rnf-Nqr subunit, membrane protein Pkinase PF00069.20 KFM03382.1 - 3e-52 177.3 0.0 4.5e-52 176.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM03382.1 - 4.1e-32 111.2 0.0 4.6e-15 55.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase TGF_beta_GS PF08515.7 KFM03382.1 - 1.7e-17 62.3 0.3 3.4e-17 61.4 0.2 1.5 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.18 KFM03382.1 - 1.3e-11 44.9 14.2 1.3e-11 44.9 9.9 2.6 2 0 0 2 2 2 1 Activin types I and II receptor domain APH PF01636.18 KFM03382.1 - 0.041 13.5 0.0 0.11 12.1 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.20 KFM03383.1 - 2.5e-53 180.8 0.0 3.8e-53 180.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM03383.1 - 1.5e-32 112.6 0.1 2.1e-32 112.1 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase TGF_beta_GS PF08515.7 KFM03383.1 - 9.9e-17 59.9 0.4 2e-16 58.9 0.3 1.6 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.18 KFM03383.1 - 8.8e-10 39.0 12.8 8.8e-10 39.0 8.9 1.8 2 0 0 2 2 2 1 Activin types I and II receptor domain TMEM154 PF15102.1 KFM03383.1 - 0.002 17.8 0.0 0.0032 17.1 0.0 1.2 1 0 0 1 1 1 1 TMEM154 protein family APH PF01636.18 KFM03383.1 - 0.009 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF4083 PF13314.1 KFM03383.1 - 0.076 12.8 1.4 0.15 11.9 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Choline_kinase PF01633.15 KFM03383.1 - 0.09 12.3 0.5 8.6 5.8 0.0 3.0 2 1 1 4 4 4 0 Choline/ethanolamine kinase PNP_UDP_1 PF01048.15 KFM03384.1 - 2.4e-21 75.7 0.1 3e-21 75.4 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily DAP PF15228.1 KFM03385.1 - 4.1e-08 33.8 2.8 8e-08 32.9 1.9 1.6 1 1 0 1 1 1 1 Death-associated protein Ank_2 PF12796.2 KFM03386.1 - 9.4e-80 263.0 20.1 2.3e-23 82.3 0.0 5.3 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KFM03386.1 - 4.9e-58 190.1 9.5 1.3e-06 27.8 0.0 11.4 11 0 0 11 11 11 9 Ankyrin repeat Ank_4 PF13637.1 KFM03386.1 - 9.8e-52 172.4 4.0 8e-10 38.9 0.0 8.2 2 2 7 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM03386.1 - 1.6e-40 133.0 3.7 0.00015 21.6 0.0 10.9 11 0 0 11 11 10 7 Ankyrin repeat Ank_5 PF13857.1 KFM03386.1 - 9.4e-37 124.2 5.3 1.4e-09 37.8 0.0 8.1 3 2 6 9 9 8 7 Ankyrin repeats (many copies) TPR_11 PF13414.1 KFM03386.1 - 7.4e-11 41.5 8.7 1.7e-06 27.5 2.1 2.7 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.12 KFM03386.1 - 1.9e-06 27.3 11.1 0.36 10.8 0.2 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 KFM03386.1 - 8.3e-05 22.3 1.7 0.011 15.5 0.7 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_16 PF13191.1 KFM03386.1 - 0.0004 20.4 0.8 0.0017 18.3 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain TPR_16 PF13432.1 KFM03386.1 - 0.00082 19.9 7.6 0.036 14.7 0.1 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFM03386.1 - 0.0025 17.3 7.4 3.7 7.3 0.9 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFM03386.1 - 0.0059 16.2 0.7 0.26 11.1 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFM03386.1 - 0.0073 16.6 3.9 1.6 9.1 0.2 3.0 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFM03386.1 - 0.0096 16.4 4.6 0.077 13.6 1.9 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFM03386.1 - 0.017 15.0 0.1 0.017 15.0 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 KFM03386.1 - 0.063 13.5 1.7 0.99 9.7 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat MAT1 PF06391.8 KFM03386.1 - 0.6 9.6 5.4 1.4 8.4 3.8 1.5 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 WD40 PF00400.27 KFM03387.1 - 4.3e-62 203.9 28.1 1.3e-11 43.9 1.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat U-box PF04564.10 KFM03387.1 - 1.4e-25 89.0 0.2 2.9e-25 88.0 0.1 1.6 1 0 0 1 1 1 1 U-box domain SAM_2 PF07647.12 KFM03387.1 - 6e-11 42.0 0.2 1e-10 41.2 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFM03387.1 - 1.9e-10 40.7 0.2 3.7e-10 39.8 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) eIF2A PF08662.6 KFM03387.1 - 1.1e-05 25.2 0.0 0.16 11.7 0.0 3.3 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A DUF3312 PF11768.3 KFM03387.1 - 2.2e-05 22.9 0.0 0.074 11.2 0.0 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF3312) SAM_PNT PF02198.11 KFM03387.1 - 7.8e-05 22.3 0.0 0.00038 20.1 0.0 2.1 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain zf-Nse PF11789.3 KFM03387.1 - 0.00043 19.7 0.0 0.0013 18.2 0.0 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF2415 PF10313.4 KFM03387.1 - 0.042 13.5 1.6 4.5 7.0 0.0 3.8 3 0 0 3 3 3 0 Uncharacterised protein domain (DUF2415) RINGv PF12906.2 KFM03388.1 - 7.1e-15 54.7 8.1 1.5e-14 53.7 5.6 1.6 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 KFM03388.1 - 0.00025 20.9 4.2 0.00025 20.9 2.9 1.7 2 0 0 2 2 2 1 FANCL C-terminal domain zf-RING_2 PF13639.1 KFM03388.1 - 0.0013 18.5 4.9 0.0027 17.5 3.4 1.6 1 0 0 1 1 1 1 Ring finger domain DUF1139 PF06599.6 KFM03388.1 - 0.12 11.5 0.1 5.3 6.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1139) zf-rbx1 PF12678.2 KFM03388.1 - 0.33 11.1 2.1 0.68 10.0 1.4 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger DUF1977 PF09320.6 KFM03389.1 - 5.1e-34 116.7 3.8 1e-33 115.7 2.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 KFM03389.1 - 3.2e-26 90.8 0.3 8e-26 89.5 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain GntP_permease PF02447.11 KFM03389.1 - 0.015 13.8 0.0 0.018 13.5 0.0 1.1 1 0 0 1 1 1 0 GntP family permease DUF401 PF04165.7 KFM03389.1 - 0.077 12.0 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF401) Xan_ur_permease PF00860.15 KFM03390.1 - 1.1e-58 198.5 11.6 1.5e-58 198.1 8.1 1.1 1 0 0 1 1 1 1 Permease family PAM2 PF07145.10 KFM03391.1 - 9.7e-08 31.0 0.8 3e-07 29.4 0.5 1.9 1 0 0 1 1 1 1 Ataxin-2 C-terminal region RE_HindIII PF09518.5 KFM03391.1 - 0.023 13.6 1.5 0.028 13.3 1.1 1.1 1 0 0 1 1 1 0 HindIII restriction endonuclease rve_3 PF13683.1 KFM03391.1 - 0.27 10.7 1.5 1.4 8.4 0.5 2.0 1 1 1 2 2 2 0 Integrase core domain RRM_5 PF13893.1 KFM03392.1 - 5.5e-28 96.5 0.0 3.4e-13 49.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM03392.1 - 1.3e-19 69.9 0.0 1.4e-11 44.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFM03392.1 - 7.3e-09 35.1 0.0 0.00049 19.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_jaz PF12171.3 KFM03392.1 - 0.13 12.4 7.3 0.15 12.2 1.0 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM03392.1 - 4.3 7.6 10.3 8.1 6.8 1.4 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Fes1 PF08609.5 KFM03393.1 - 0.0039 17.6 1.6 0.01 16.2 1.1 1.7 1 0 0 1 1 1 1 Nucleotide exchange factor Fes1 CDC14 PF08045.6 KFM03393.1 - 0.048 12.7 6.7 0.12 11.5 0.5 2.9 1 1 2 3 3 3 0 Cell division control protein 14, SIN component HEAT_2 PF13646.1 KFM03393.1 - 0.052 13.8 1.0 0.3 11.3 0.0 2.6 3 0 0 3 3 3 0 HEAT repeats HEAT_EZ PF13513.1 KFM03393.1 - 0.074 13.5 0.2 0.28 11.7 0.2 2.1 1 0 0 1 1 1 0 HEAT-like repeat Rab5-bind PF09311.6 KFM03393.1 - 0.6 9.9 10.6 0.029 14.2 2.6 2.1 2 1 0 2 2 2 0 Rabaptin-like protein Vinculin PF01044.14 KFM03394.1 - 0 1034.7 37.8 3.6e-215 717.0 17.0 2.1 1 1 1 2 2 2 2 Vinculin family DivIC PF04977.10 KFM03394.1 - 5.9 6.4 8.5 0.77 9.2 0.5 3.5 3 0 0 3 3 3 0 Septum formation initiator LRR_8 PF13855.1 KFM03395.1 - 3.7e-46 154.7 49.5 3.9e-14 52.1 2.2 5.2 2 1 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 KFM03395.1 - 1.4e-32 110.7 39.0 3.7e-07 29.6 3.8 7.0 2 2 5 8 8 8 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFM03395.1 - 2.1e-23 82.4 0.7 7.6e-10 38.5 0.0 3.4 2 1 2 4 4 4 3 Leucine rich repeats (6 copies) LRR_1 PF00560.28 KFM03395.1 - 6.7e-21 71.1 34.4 0.014 15.2 1.0 10.8 11 0 0 11 11 11 8 Leucine Rich Repeat LRR_7 PF13504.1 KFM03395.1 - 6.8e-09 34.4 39.6 1 9.8 0.5 10.8 11 0 0 11 11 11 6 Leucine rich repeat LRR_6 PF13516.1 KFM03395.1 - 1.2e-08 34.1 36.9 0.4 10.8 0.8 10.4 10 1 1 11 11 11 4 Leucine Rich repeat LRR_9 PF14580.1 KFM03395.1 - 2.1e-08 33.9 4.5 0.024 14.2 0.1 3.6 1 1 3 4 4 4 3 Leucine-rich repeat LRRNT PF01462.13 KFM03395.1 - 0.0045 16.4 1.8 0.0045 16.4 1.3 2.6 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain HSP70 PF00012.15 KFM03396.1 - 1.6e-257 855.3 8.0 1.7e-257 855.1 5.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFM03396.1 - 1.4e-18 66.5 1.7 4.8e-16 58.2 0.2 2.4 2 1 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 KFM03396.1 - 7.7e-06 25.6 0.2 1.5e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 KFM03396.1 - 0.00015 21.5 7.1 0.83 9.5 0.0 4.5 3 1 0 3 3 3 2 Cell division protein FtsA eRF1_2 PF03464.10 KFM03397.1 - 1.1e-45 155.2 0.1 1.7e-45 154.5 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 KFM03397.1 - 3.6e-39 133.5 0.3 7.7e-39 132.4 0.2 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 KFM03397.1 - 4e-23 81.4 0.0 7.2e-23 80.6 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 Ribosomal_L7Ae PF01248.21 KFM03397.1 - 0.0044 16.5 0.0 0.0089 15.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family WD40 PF00400.27 KFM03398.1 - 2.2e-60 198.5 17.0 5.1e-10 38.8 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Beta-TrCP_D PF12125.3 KFM03398.1 - 5.9e-28 96.1 2.3 1.1e-27 95.2 1.6 1.5 1 0 0 1 1 1 1 D domain of beta-TrCP F-box-like PF12937.2 KFM03398.1 - 1.5e-09 37.4 0.2 3.8e-09 36.1 0.2 1.7 1 0 0 1 1 1 1 F-box-like Nucleoporin_N PF08801.6 KFM03398.1 - 1.1e-07 31.0 3.8 0.009 14.8 0.0 3.9 1 1 3 4 4 4 2 Nup133 N terminal like F-box PF00646.28 KFM03398.1 - 1.4e-07 31.0 0.0 4e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 KFM03398.1 - 0.00046 18.4 9.0 0.24 9.4 0.2 4.3 1 1 3 4 4 4 3 Nucleoporin Nup120/160 DUF4508 PF14969.1 KFM03398.1 - 0.034 14.1 0.0 0.076 13.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) PQQ_3 PF13570.1 KFM03398.1 - 0.096 12.9 0.1 60 4.1 0.0 3.8 3 1 1 4 4 4 0 PQQ-like domain Peptidase_M1 PF01433.15 KFM03399.1 - 1.7e-108 363.2 0.1 2.3e-108 362.7 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 KFM03399.1 - 1.6e-44 152.5 1.9 5.9e-44 150.6 0.6 1.9 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KFM03399.1 - 2.4e-15 56.7 0.1 2.4e-15 56.7 0.1 2.2 4 0 0 4 4 4 1 Peptidase MA superfamily DUF4560 PF15118.1 KFM03399.1 - 0.086 12.6 0.1 0.4 10.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4560) DUF1570 PF07607.6 KFM03399.1 - 1.4 8.9 4.7 2.7 8.0 0.3 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1570) Biopterin_H PF00351.16 KFM03401.1 - 3e-182 604.7 0.2 3.7e-182 604.4 0.1 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase DUF3548 PF12068.3 KFM03402.1 - 1.1e-88 296.1 1.4 1.6e-88 295.5 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3548) RabGAP-TBC PF00566.13 KFM03402.1 - 1.3e-47 162.0 10.6 2.1e-47 161.3 7.4 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF561 PF04481.7 KFM03402.1 - 0.17 10.7 0.0 0.3 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF561) Ras PF00071.17 KFM03403.1 - 1.5e-43 147.9 0.1 1.8e-43 147.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM03403.1 - 2.9e-12 47.1 0.0 5.3e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM03403.1 - 7.9e-10 38.2 0.1 9.7e-10 37.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFM03403.1 - 2e-05 24.1 0.0 2.6e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RHH_1 PF01402.16 KFM03403.1 - 0.073 12.9 0.2 0.58 10.1 0.0 2.3 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family PduV-EutP PF10662.4 KFM03403.1 - 0.074 12.5 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF92 PF01940.11 KFM03404.1 - 9.6e-73 244.0 4.5 9.6e-73 244.0 3.1 1.3 2 0 0 2 2 2 1 Integral membrane protein DUF92 EI24 PF07264.6 KFM03404.1 - 2 7.7 16.2 0.037 13.4 2.2 2.8 3 0 0 3 3 3 0 Etoposide-induced protein 2.4 (EI24) zf-C3H1 PF10650.4 KFM03405.1 - 1.4e-09 37.2 7.4 3.2e-09 36.0 5.2 1.7 1 0 0 1 1 1 1 Putative zinc-finger domain TPR_19 PF14559.1 KFM03405.1 - 1.3e-05 25.3 2.2 0.68 10.3 0.0 5.9 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFM03405.1 - 6.2e-05 23.2 5.3 3.4 8.5 0.0 6.4 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFM03405.1 - 9.2e-05 22.3 4.6 1.2 9.5 0.1 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFM03405.1 - 0.0012 18.4 14.3 0.059 13.0 0.3 4.9 5 2 1 6 6 6 3 TPR repeat LRR_8 PF13855.1 KFM03406.1 - 6.5e-86 282.0 57.1 5.1e-15 54.9 2.0 8.6 2 2 8 10 10 10 9 Leucine rich repeat LRR_4 PF12799.2 KFM03406.1 - 3.9e-48 160.3 37.1 4e-08 32.7 0.0 9.8 6 3 3 10 10 10 9 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFM03406.1 - 1.2e-36 125.3 0.0 2.9e-12 46.4 0.0 4.8 2 1 3 5 5 5 4 Leucine rich repeats (6 copies) LRR_1 PF00560.28 KFM03406.1 - 4.2e-32 105.2 43.5 0.031 14.2 0.3 17.6 17 1 1 18 18 18 11 Leucine Rich Repeat LRR_7 PF13504.1 KFM03406.1 - 1.9e-18 63.2 37.3 0.44 10.9 0.3 15.6 15 0 0 15 15 15 5 Leucine rich repeat 7tm_1 PF00001.16 KFM03406.1 - 1.2e-16 60.6 15.9 1.7e-16 60.1 11.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_6 PF13516.1 KFM03406.1 - 3.6e-11 41.9 37.1 0.29 11.3 0.2 14.8 14 2 1 15 15 15 3 Leucine Rich repeat LRR_9 PF14580.1 KFM03406.1 - 3.2e-10 39.8 5.7 0.31 10.5 0.1 5.0 1 1 4 5 5 5 4 Leucine-rich repeat 7TM_GPCR_Srx PF10328.4 KFM03406.1 - 0.29 10.1 15.8 0.023 13.8 7.2 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx Tetraspannin PF00335.15 KFM03407.1 - 3e-50 170.5 18.2 3.6e-50 170.3 12.6 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF4131 PF13567.1 KFM03407.1 - 1.9 7.8 7.0 28 4.0 4.8 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Claudin_2 PF13903.1 KFM03407.1 - 2.1 8.0 10.4 6 6.5 6.4 2.1 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Tic20 PF09685.5 KFM03407.1 - 6.8 6.7 13.6 0.21 11.5 4.7 1.8 2 0 0 2 2 2 0 Tic20-like protein Y_phosphatase PF00102.22 KFM03408.1 - 2.6e-77 259.3 1.3 3.1e-77 259.0 0.1 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFM03408.1 - 0.0003 20.3 0.0 0.00074 19.1 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFM03408.1 - 0.0014 18.9 0.0 0.0034 17.6 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KFM03408.1 - 0.062 13.3 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate fn3 PF00041.16 KFM03409.1 - 6.2e-157 510.1 43.3 7.3e-13 48.4 0.6 18.6 19 0 0 19 19 19 16 Fibronectin type III domain Y_phosphatase PF00102.22 KFM03409.1 - 1.7e-80 269.7 0.3 3e-80 268.9 0.2 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF4232 PF14016.1 KFM03409.1 - 0.00079 19.0 4.2 2.7 7.6 0.0 5.6 6 0 0 6 6 6 1 Protein of unknown function (DUF4232) DSPc PF00782.15 KFM03409.1 - 0.0018 17.8 0.0 0.0048 16.4 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFM03409.1 - 0.004 17.4 0.0 0.009 16.2 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KFM03409.1 - 0.0043 17.0 0.0 0.0085 16.1 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Interfer-bind PF09294.5 KFM03409.1 - 0.0047 16.9 12.4 4 7.5 0.2 7.7 9 0 0 9 9 9 2 Interferon-alpha/beta receptor, fibronectin type III SusE PF14292.1 KFM03409.1 - 0.72 9.6 16.8 8.9 6.1 0.0 7.9 11 0 0 11 11 11 0 SusE outer membrane protein CaKB PF03185.10 KFM03410.1 - 1.9e-67 226.5 0.1 2.2e-67 226.3 0.1 1.0 1 0 0 1 1 1 1 Calcium-activated potassium channel, beta subunit LAT PF15234.1 KFM03410.1 - 0.11 11.9 0.4 0.27 10.6 0.3 1.6 1 0 0 1 1 1 0 Linker for activation of T-cells NOT2_3_5 PF04153.13 KFM03411.1 - 5.4e-34 116.9 0.2 1e-33 116.0 0.1 1.5 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family MRF_C2 PF13888.1 KFM03412.1 - 9.5e-58 193.9 3.7 2.9e-57 192.4 2.6 1.9 1 0 0 1 1 1 1 Myelin gene regulatory factor C-terminal domain 2 NDT80_PhoG PF05224.7 KFM03412.1 - 1.5e-26 93.5 0.5 2.7e-25 89.4 0.3 2.5 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family MRF_C1 PF13887.1 KFM03412.1 - 5e-20 70.2 0.8 5e-20 70.2 0.5 2.5 3 0 0 3 3 3 1 Myelin gene regulatory factor -C-terminal domain 1 Peptidase_S74 PF13884.1 KFM03412.1 - 1.9e-13 50.3 0.1 3.9e-13 49.3 0.1 1.6 1 0 0 1 1 1 1 Chaperone of endosialidase Sec2p PF06428.6 KFM03413.1 - 6.3e-20 70.9 6.4 1.3e-19 69.9 4.4 1.5 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p CHASE3 PF05227.8 KFM03413.1 - 0.036 13.7 3.3 0.077 12.6 2.3 1.4 1 0 0 1 1 1 0 CHASE3 domain DUF3584 PF12128.3 KFM03413.1 - 0.13 9.5 7.7 0.17 9.1 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Bestrophin PF01062.16 KFM03414.1 - 3.7e-98 328.1 6.3 4.6e-98 327.7 4.4 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Asp PF00026.18 KFM03415.1 - 3e-116 388.0 0.2 3.5e-116 387.8 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KFM03415.1 - 1e-07 32.0 0.0 1.9e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal A1_Propeptide PF07966.7 KFM03415.1 - 4.2e-06 26.3 1.0 7.4e-06 25.5 0.7 1.4 1 0 0 1 1 1 1 A1 Propeptide TAXi_C PF14541.1 KFM03415.1 - 4.5e-05 23.0 0.0 0.00011 21.7 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Cpn60_TCP1 PF00118.19 KFM03416.1 - 1.4e-136 455.9 9.9 1.6e-136 455.7 6.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2529 PF10740.4 KFM03416.1 - 0.067 12.6 0.1 0.8 9.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2529) IRS PF02174.12 KFM03417.1 - 4.7e-27 93.5 0.1 9.9e-27 92.4 0.1 1.5 1 0 0 1 1 1 1 PTB domain (IRS-1 type) YEATS PF03366.11 KFM03418.1 - 9.7e-33 111.7 0.7 1.6e-32 111.0 0.5 1.4 1 0 0 1 1 1 1 YEATS family DUF3166 PF11365.3 KFM03418.1 - 0.0021 18.4 0.2 0.01 16.2 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3166) DUF4071 PF13281.1 KFM03418.1 - 0.008 15.0 0.5 0.012 14.5 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4071) DUF1664 PF07889.7 KFM03418.1 - 0.0089 15.8 1.1 0.014 15.1 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) DUF342 PF03961.8 KFM03418.1 - 0.06 11.7 1.1 0.076 11.4 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF904 PF06005.7 KFM03418.1 - 0.37 11.1 5.1 0.18 12.1 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Bap31 PF05529.7 KFM03418.1 - 0.48 9.8 5.3 0.81 9.1 3.6 1.5 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like DivIC PF04977.10 KFM03418.1 - 0.8 9.2 3.4 1.8 8.1 2.4 1.6 1 0 0 1 1 1 0 Septum formation initiator RRM_6 PF14259.1 KFM03419.1 - 4.9e-07 29.6 0.0 7.9e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFM03419.1 - 0.00018 21.1 0.0 0.00029 20.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc PF12871.2 KFM03419.1 - 1 9.9 55.4 3.6 8.1 38.4 1.9 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Peptidase_M14 PF00246.19 KFM03420.1 - 7.2e-68 229.1 0.1 8.8e-68 228.9 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.1 KFM03420.1 - 1.2e-11 44.5 0.0 2.1e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain AstE_AspA PF04952.9 KFM03420.1 - 1.4e-07 30.7 0.2 2.5e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF4480 PF13715.1 KFM03420.1 - 1.8e-07 31.0 0.0 2.8e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4480) Dioxygenase_C PF00775.16 KFM03420.1 - 0.0096 15.2 0.0 0.023 13.9 0.0 1.6 1 1 0 1 1 1 1 Dioxygenase phage_tail_N PF08400.5 KFM03420.1 - 0.14 11.8 0.0 0.51 10.0 0.0 1.7 1 1 0 1 1 1 0 Prophage tail fibre N-terminal SWIB PF02201.13 KFM03421.1 - 1.2e-19 69.7 0.2 2.5e-19 68.7 0.1 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain zf-C3HC4_3 PF13920.1 KFM03421.1 - 2.8e-11 42.8 9.7 2.8e-11 42.8 6.7 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RanBP PF00641.13 KFM03421.1 - 5.4e-09 34.9 1.9 5.4e-09 34.9 1.3 2.6 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others zf-C3HC4_2 PF13923.1 KFM03421.1 - 2.6e-06 27.3 10.7 2.6e-06 27.3 7.4 2.6 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DZR PF12773.2 KFM03421.1 - 0.058 13.2 12.9 0.75 9.6 0.7 2.9 2 0 0 2 2 2 0 Double zinc ribbon zf-FPG_IleRS PF06827.9 KFM03421.1 - 0.2 11.3 0.1 0.2 11.3 0.1 3.6 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS zf-RING_2 PF13639.1 KFM03421.1 - 0.64 9.8 14.1 0.05 13.4 6.1 2.1 2 0 0 2 2 2 0 Ring finger domain TPT PF03151.11 KFM03422.1 - 4.7e-23 81.5 15.4 1.3e-21 76.8 10.7 3.1 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.15 KFM03422.1 - 3.7e-07 30.2 7.4 3.7e-07 30.2 5.1 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 KFM03422.1 - 0.36 9.7 14.1 2 7.2 9.8 2.0 1 1 0 1 1 1 0 UAA transporter family Nup84_Nup100 PF04121.8 KFM03423.1 - 3.7e-227 755.4 15.7 4.4e-227 755.1 10.9 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Ras PF00071.17 KFM03424.1 - 2.3e-57 192.8 0.3 2.7e-57 192.7 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM03424.1 - 2.7e-21 76.2 0.1 4.1e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM03424.1 - 8.8e-09 34.8 0.2 9.2e-09 34.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFM03424.1 - 1.9e-06 27.4 0.3 4e-06 26.3 0.2 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFM03424.1 - 4.2e-05 23.4 0.0 7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 KFM03424.1 - 0.00039 19.2 0.0 0.00061 18.5 0.0 1.4 1 1 0 1 1 1 1 G-protein alpha subunit AAA_22 PF13401.1 KFM03424.1 - 0.12 12.5 1.5 5 7.2 0.6 2.7 2 1 0 2 2 2 0 AAA domain MDM1 PF15501.1 KFM03425.1 - 4.8e-149 497.9 40.8 1.8e-89 301.2 15.6 2.8 1 1 2 3 3 3 2 Nuclear protein MDM1 IL22 PF14565.1 KFM03426.1 - 1.6e-69 232.3 3.3 1.8e-69 232.1 2.3 1.0 1 0 0 1 1 1 1 Interleukin 22 IL-10-related T-cell-derived-inducible factor IL10 PF00726.12 KFM03426.1 - 9.5e-07 28.2 0.6 1.1e-06 28.1 0.4 1.1 1 0 0 1 1 1 1 Interleukin 10 Baculo_gp41 PF04700.7 KFM03426.1 - 0.034 13.5 0.1 0.048 13.0 0.1 1.3 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region CENP-F_leu_zip PF10473.4 KFM03426.1 - 0.042 13.6 0.5 0.069 13.0 0.3 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Col_cuticle_N PF01484.12 KFM03426.1 - 1.9 8.2 4.7 4.8 6.9 1.5 2.5 2 1 1 3 3 3 0 Nematode cuticle collagen N-terminal domain IL10 PF00726.12 KFM03427.1 - 1e-08 34.6 0.0 1.9e-08 33.7 0.0 1.6 1 1 0 1 1 1 1 Interleukin 10 IL22 PF14565.1 KFM03427.1 - 2.3e-05 24.4 0.0 3.8e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 Interleukin 22 IL-10-related T-cell-derived-inducible factor IFN-gamma PF00714.12 KFM03428.1 - 2.4e-26 92.1 3.1 2.9e-26 91.9 2.1 1.1 1 0 0 1 1 1 1 Interferon gamma DUF4422 PF14393.1 KFM03428.1 - 0.064 12.8 0.5 0.075 12.6 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4422) DUF948 PF06103.6 KFM03428.1 - 0.087 12.6 1.2 0.95 9.3 0.8 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Mt_ATP-synt_B PF05405.9 KFM03428.1 - 0.84 9.0 5.2 2 7.8 0.1 2.4 1 1 1 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) IncA PF04156.9 KFM03428.1 - 2.6 7.5 7.2 14 5.2 5.0 1.9 1 1 0 1 1 1 0 IncA protein RVT_1 PF00078.22 KFM03429.1 - 0.084 12.2 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.20 KFM03430.1 - 3.8e-60 203.2 0.0 5.4e-60 202.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM03430.1 - 2.8e-23 82.3 0.0 6e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFM03430.1 - 1.9e-06 27.8 0.0 0.00021 21.1 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KFM03430.1 - 0.002 17.2 0.3 0.004 16.2 0.2 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KFM03430.1 - 0.0023 17.5 2.6 0.0051 16.4 1.8 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 KFM03430.1 - 0.013 14.8 1.1 0.11 11.7 0.0 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 KFM03430.1 - 0.019 14.3 2.0 0.14 11.5 1.4 2.0 1 1 0 1 1 1 0 RIO1 family Kinase-like PF14531.1 KFM03430.1 - 0.048 12.6 0.0 0.21 10.4 0.0 1.9 2 0 0 2 2 2 0 Kinase-like TIP120 PF08623.5 KFM03431.1 - 1.3e-67 226.5 6.5 2.6e-65 219.1 0.4 4.5 4 1 0 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 KFM03431.1 - 8.6e-27 93.2 2.5 0.0054 16.9 0.0 9.8 6 4 3 9 9 9 6 HEAT repeats HEAT PF02985.17 KFM03431.1 - 8.9e-21 72.0 12.7 0.0079 16.1 0.0 12.1 14 0 0 14 14 12 4 HEAT repeat HEAT_EZ PF13513.1 KFM03431.1 - 6.3e-20 71.0 7.6 0.005 17.2 0.1 13.3 12 4 4 16 16 15 4 HEAT-like repeat UME PF08064.8 KFM03431.1 - 2.2e-13 50.1 9.6 0.0069 16.3 0.0 6.9 7 1 1 8 8 7 4 UME (NUC010) domain Cnd1 PF12717.2 KFM03431.1 - 1.2e-10 41.5 8.4 0.25 11.1 0.0 6.9 5 1 1 6 6 6 3 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 KFM03431.1 - 1.1e-09 38.0 0.1 0.15 11.3 0.0 6.0 5 2 0 5 5 5 2 CLASP N terminal Vac14_Fab1_bd PF12755.2 KFM03431.1 - 4.7e-09 36.5 7.1 0.0082 16.5 0.1 7.4 8 1 1 9 9 9 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 KFM03431.1 - 2.4e-06 26.5 0.4 3.9e-05 22.5 0.6 7.3 8 1 0 8 8 8 2 RNAPII transcription regulator C-terminal DUF1981 PF09324.5 KFM03431.1 - 0.00064 19.1 1.4 2.4 7.7 0.0 5.6 5 1 1 6 6 6 1 Domain of unknown function (DUF1981) VHS PF00790.14 KFM03431.1 - 0.0054 16.3 0.5 1.5 8.4 0.1 4.1 3 0 0 3 3 3 1 VHS domain RasGEF_N_2 PF14663.1 KFM03431.1 - 0.077 12.9 4.4 4.1 7.3 0.1 4.8 5 0 0 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF3385 PF11865.3 KFM03431.1 - 0.093 12.6 6.7 0.45 10.4 0.0 5.2 6 0 0 6 6 5 0 Domain of unknown function (DUF3385) Urb2 PF10441.4 KFM03431.1 - 5.5 6.5 7.7 7.7 6.0 0.1 3.9 4 1 0 4 4 4 0 Urb2/Npa2 family 7tm_4 PF13853.1 KFM03432.1 - 1.8e-33 115.4 5.9 1.8e-33 115.4 4.1 2.8 3 0 0 3 3 3 1 Olfactory receptor 7tm_1 PF00001.16 KFM03432.1 - 2.6e-26 92.3 12.7 4e-26 91.7 8.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MSC PF09402.5 KFM03432.1 - 0.13 10.9 1.3 0.25 10.0 0.9 1.4 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain DUF1731 PF08338.6 KFM03433.1 - 8.7e-18 63.5 0.0 1.8e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) NAD_binding_10 PF13460.1 KFM03433.1 - 1.9e-11 44.2 0.0 2.6e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFM03433.1 - 5.7e-09 35.7 0.0 4e-08 32.9 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KFM03433.1 - 0.039 12.8 0.1 0.28 10.0 0.0 2.2 3 0 0 3 3 3 0 RmlD substrate binding domain adh_short PF00106.20 KFM03433.1 - 0.085 12.7 0.2 7.9 6.3 0.0 2.3 1 1 1 2 2 2 0 short chain dehydrogenase EIIC-GAT PF03611.9 KFM03434.1 - 0.23 10.2 2.3 0.24 10.1 1.6 1.0 1 0 0 1 1 1 0 PTS system sugar-specific permease component Keratin PF02422.11 KFM03435.1 - 6.8e-37 125.3 12.1 6.8e-37 125.3 8.4 2.1 1 1 1 2 2 2 2 Keratin Keratin PF02422.11 KFM03436.1 - 2.5e-35 120.3 7.7 2.8e-35 120.1 5.3 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 KFM03437.1 - 5.4e-32 109.6 7.9 5.9e-32 109.5 5.5 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 KFM03438.1 - 3.8e-20 71.6 8.8 4e-20 71.5 6.1 1.0 1 0 0 1 1 1 1 Keratin LELP1 PF15042.1 KFM03438.1 - 0.58 10.3 7.3 0.68 10.1 5.1 1.1 1 0 0 1 1 1 0 Late cornified envelope-like proline-rich protein 1 DUF3432 PF11914.3 KFM03438.1 - 0.59 10.1 9.0 0.87 9.6 6.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3432) Keratin PF02422.11 KFM03439.1 - 1e-20 73.4 5.9 1.2e-20 73.3 4.1 1.0 1 0 0 1 1 1 1 Keratin DUF3432 PF11914.3 KFM03439.1 - 0.38 10.8 2.9 0.45 10.5 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) LELP1 PF15042.1 KFM03439.1 - 5.9 7.1 9.5 8.4 6.6 6.6 1.3 1 0 0 1 1 1 0 Late cornified envelope-like proline-rich protein 1 Keratin PF02422.11 KFM03440.1 - 4.5e-20 71.4 6.8 4.6e-20 71.4 4.7 1.0 1 0 0 1 1 1 1 Keratin DUF3432 PF11914.3 KFM03440.1 - 0.3 11.1 3.4 0.35 10.9 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) LELP1 PF15042.1 KFM03440.1 - 3.8 7.7 9.7 5.7 7.1 6.8 1.3 1 0 0 1 1 1 0 Late cornified envelope-like proline-rich protein 1 Keratin PF02422.11 KFM03441.1 - 1.2e-24 86.1 4.9 1.2e-24 86.0 3.4 1.0 1 0 0 1 1 1 1 Keratin LELP1 PF15042.1 KFM03441.1 - 2.5 8.3 5.9 3 8.0 4.1 1.1 1 0 0 1 1 1 0 Late cornified envelope-like proline-rich protein 1 Keratin PF02422.11 KFM03442.1 - 3.7e-17 62.0 5.4 3.8e-17 62.0 3.8 1.0 1 0 0 1 1 1 1 Keratin DUF3432 PF11914.3 KFM03442.1 - 1.5 8.8 8.3 1.8 8.6 5.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3432) LELP1 PF15042.1 KFM03442.1 - 1.8 8.7 7.8 2.1 8.5 5.4 1.1 1 0 0 1 1 1 0 Late cornified envelope-like proline-rich protein 1 Keratin PF02422.11 KFM03443.1 - 7.8e-06 25.7 5.8 1.4e-05 24.9 4.0 1.5 1 1 0 1 1 1 1 Keratin Keratin PF02422.11 KFM03444.1 - 2.7e-23 81.7 6.5 2.9e-23 81.6 4.5 1.0 1 0 0 1 1 1 1 Keratin LELP1 PF15042.1 KFM03444.1 - 1.8 8.7 9.7 3.1 8.0 6.8 1.3 1 1 0 1 1 1 0 Late cornified envelope-like proline-rich protein 1 Keratin PF02422.11 KFM03445.1 - 1.4e-21 76.2 3.9 1.4e-21 76.2 2.7 1.0 1 0 0 1 1 1 1 Keratin DUF3432 PF11914.3 KFM03445.1 - 0.034 14.1 0.7 0.037 14.0 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) Keratin PF02422.11 KFM03446.1 - 7.7e-13 48.2 30.1 2.1e-11 43.6 20.9 2.0 1 1 0 1 1 1 1 Keratin DUF3432 PF11914.3 KFM03446.1 - 0.0016 18.4 1.7 0.0026 17.7 1.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3432) Keratin PF02422.11 KFM03447.1 - 2.6e-16 59.3 6.1 2.7e-16 59.3 4.3 1.0 1 0 0 1 1 1 1 Keratin DUF3432 PF11914.3 KFM03447.1 - 0.00085 19.3 2.1 0.001 19.0 1.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3432) Keratin PF02422.11 KFM03448.1 - 1.8e-15 56.6 11.3 2.1e-15 56.4 7.8 1.1 1 0 0 1 1 1 1 Keratin PP2C PF00481.16 KFM03448.1 - 0.14 11.5 0.1 0.19 11.1 0.1 1.1 1 0 0 1 1 1 0 Protein phosphatase 2C TIL PF01826.12 KFM03448.1 - 0.27 11.3 5.7 0.44 10.6 4.0 1.4 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain Keratin PF02422.11 KFM03449.1 - 8.9e-13 48.0 2.8 9.2e-13 47.9 1.9 1.1 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 KFM03450.1 - 4.3e-14 52.2 27.0 3.1e-13 49.5 18.7 1.9 1 1 0 1 1 1 1 Keratin TIL PF01826.12 KFM03450.1 - 0.71 10.0 5.7 0.31 11.2 1.9 1.9 2 0 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain LELP1 PF15042.1 KFM03450.1 - 9.1 6.5 10.6 12 6.0 7.3 1.2 1 0 0 1 1 1 0 Late cornified envelope-like proline-rich protein 1 Keratin PF02422.11 KFM03451.1 - 1e-19 70.3 9.7 1.1e-19 70.2 6.7 1.0 1 0 0 1 1 1 1 Keratin DUF3432 PF11914.3 KFM03451.1 - 0.12 12.3 2.5 0.15 12.1 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) LELP1 PF15042.1 KFM03451.1 - 2.4 8.3 9.4 2.6 8.2 6.5 1.1 1 0 0 1 1 1 0 Late cornified envelope-like proline-rich protein 1 Potyvirid-P3 PF13608.1 KFM03455.1 - 1.4 7.9 14.6 3.8 6.5 4.3 2.1 1 1 1 2 2 2 0 Protein P3 of Potyviral polyprotein S_100 PF01023.14 KFM03456.1 - 2.7e-08 33.0 0.0 4.1e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_1 PF00036.27 KFM03456.1 - 0.0069 15.6 0.5 0.012 14.8 0.3 1.4 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 KFM03456.1 - 0.064 13.4 0.2 0.16 12.1 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain pair S_100 PF01023.14 KFM03457.1 - 1.2e-18 66.1 0.0 2.1e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_1 PF00036.27 KFM03457.1 - 9.6e-08 30.8 1.1 2e-06 26.7 0.2 2.3 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 KFM03457.1 - 1.4e-07 31.4 0.1 1.8e-07 31.1 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 KFM03457.1 - 2.4e-05 23.4 1.3 9.8e-05 21.5 0.2 2.2 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 KFM03457.1 - 4.8e-05 22.8 0.3 0.02 14.7 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 KFM03457.1 - 0.00013 21.4 1.5 0.00053 19.5 1.1 1.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_4 PF12763.2 KFM03457.1 - 0.084 12.6 0.0 0.094 12.4 0.0 1.2 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand COPI_C PF06957.6 KFM03458.1 - 1.5e-173 577.2 6.6 4.5e-170 565.7 0.2 2.4 2 1 0 2 2 2 2 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.9 KFM03458.1 - 1.4e-142 475.6 0.5 2.6e-142 474.7 0.4 1.4 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.27 KFM03458.1 - 7.8e-53 174.5 14.6 3.9e-11 42.3 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat TPR_14 PF13428.1 KFM03458.1 - 0.012 16.1 0.1 3.6 8.4 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFM03458.1 - 0.049 14.3 0.1 89 3.9 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 KFM03458.1 - 0.059 13.3 0.1 17 5.6 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc4_WD40 PF12894.2 KFM03458.1 - 0.072 12.6 1.9 0.21 11.1 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.3 KFM03458.1 - 0.13 10.3 5.2 0.32 9.0 0.1 2.9 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KFM03458.1 - 0.29 9.8 0.9 14 4.2 0.0 3.3 3 1 0 3 3 3 0 Nup133 N terminal like Nicastrin PF05450.10 KFM03459.1 - 1.9e-71 240.0 0.5 2.7e-71 239.5 0.3 1.2 1 0 0 1 1 1 1 Nicastrin Peptidase_M28 PF04389.12 KFM03459.1 - 3.4e-07 30.1 0.0 6.2e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 ig PF00047.20 KFM03460.1 - 3.3e-07 30.3 0.4 0.014 15.5 0.0 3.0 2 1 1 3 3 3 2 Immunoglobulin domain Ig_3 PF13927.1 KFM03460.1 - 8.2e-07 29.4 1.7 0.0007 20.0 1.3 2.4 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.12 KFM03460.1 - 8.4e-07 28.8 0.0 2.2e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin V-set domain Ig_2 PF13895.1 KFM03460.1 - 8.4e-05 22.6 1.6 0.11 12.6 1.0 2.9 1 1 1 2 2 2 2 Immunoglobulin domain PKD PF00801.15 KFM03460.1 - 0.0037 16.9 1.7 0.013 15.1 0.0 2.6 3 1 0 3 3 3 1 PKD domain I-set PF07679.11 KFM03460.1 - 0.0042 16.9 0.0 0.48 10.3 0.0 2.8 2 1 1 3 3 3 1 Immunoglobulin I-set domain C2-set_2 PF08205.7 KFM03460.1 - 0.019 14.8 0.3 2.8 7.9 0.0 2.7 1 1 1 2 2 2 0 CD80-like C2-set immunoglobulin domain SLAM PF06214.6 KFM03461.1 - 0.0062 16.4 0.3 0.015 15.2 0.1 1.7 2 1 0 2 2 2 1 Signaling lymphocytic activation molecule (SLAM) protein Ig_3 PF13927.1 KFM03461.1 - 0.025 15.1 2.7 0.029 14.8 0.6 2.2 2 1 0 2 2 2 0 Immunoglobulin domain PRK PF00485.13 KFM03462.1 - 3.7e-46 157.1 0.7 4.3e-46 156.9 0.5 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 KFM03462.1 - 0.15 12.3 0.5 0.41 10.9 0.3 1.8 1 1 0 1 1 1 0 AAA domain DUF106 PF01956.11 KFM03463.1 - 2.9e-42 144.0 1.0 3.3e-42 143.8 0.7 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF106 ATG19_autophagy PF12744.2 KFM03463.1 - 0.0016 17.7 1.3 0.0021 17.3 0.9 1.1 1 0 0 1 1 1 1 Autophagy protein Atg19, Atg8-binding Exonuc_VII_L PF02601.10 KFM03463.1 - 0.01 15.0 0.1 0.01 15.0 0.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4337 PF14235.1 KFM03463.1 - 0.023 14.5 0.6 0.036 13.9 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) TRAM1 PF08390.6 KFM03463.1 - 0.03 13.8 0.0 0.059 12.8 0.0 1.4 1 0 0 1 1 1 0 TRAM1-like protein OmpH PF03938.9 KFM03463.1 - 0.033 14.1 4.1 0.045 13.6 2.8 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DivIC PF04977.10 KFM03463.1 - 0.072 12.5 0.4 0.072 12.5 0.3 2.4 1 1 1 2 2 2 0 Septum formation initiator 60KD_IMP PF02096.15 KFM03463.1 - 0.084 12.5 0.1 0.1 12.2 0.1 1.1 1 0 0 1 1 1 0 60Kd inner membrane protein TMPIT PF07851.8 KFM03463.1 - 0.29 10.1 2.7 2.7 6.9 0.5 2.1 2 0 0 2 2 2 0 TMPIT-like protein Bap31 PF05529.7 KFM03463.1 - 0.43 10.0 7.1 0.14 11.5 3.3 1.4 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like DUF1090 PF06476.7 KFM03463.1 - 0.75 9.4 12.6 1.2 8.8 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) DUF3671 PF12420.3 KFM03463.1 - 1.4 8.9 5.7 0.14 12.1 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF3435 PF11917.3 KFM03463.1 - 3.3 6.3 6.4 4.6 5.8 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) DUF874 PF05917.6 KFM03463.1 - 5.2 5.8 11.1 6.9 5.4 7.7 1.1 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) Atg14 PF10186.4 KFM03463.1 - 5.6 5.8 7.3 7.8 5.3 5.1 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PBP_sp32 PF07222.7 KFM03463.1 - 8.7 5.4 7.0 12 4.9 4.8 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Aldedh PF00171.17 KFM03464.1 - 7.4e-171 568.5 0.0 8.5e-171 568.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MAPEG PF01124.13 KFM03465.1 - 1.3e-24 86.2 1.3 1.5e-24 86.0 0.9 1.0 1 0 0 1 1 1 1 MAPEG family LRR_8 PF13855.1 KFM03466.1 - 1.1e-14 53.9 8.9 1.7e-08 34.0 0.3 3.0 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KFM03466.1 - 3.8e-13 48.7 0.9 0.0024 17.4 0.0 3.6 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM03466.1 - 1.2e-07 30.7 9.7 0.036 14.0 0.1 6.8 7 1 1 8 8 8 3 Leucine Rich Repeat LRRNT PF01462.13 KFM03466.1 - 1.1e-05 24.7 1.0 1.1e-05 24.7 0.7 2.1 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.1 KFM03466.1 - 0.00037 20.2 9.9 2.7 8.3 0.0 5.6 5 0 0 5 5 5 2 Leucine Rich repeat LRR_7 PF13504.1 KFM03466.1 - 0.0039 17.1 11.8 9.7 6.9 0.1 6.2 7 0 0 7 7 7 2 Leucine rich repeat LRR_5 PF13306.1 KFM03466.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Leucine rich repeats (6 copies) Nuf2 PF03800.9 KFM03467.1 - 4.3e-40 137.0 0.3 4.3e-40 137.0 0.2 2.4 2 0 0 2 2 2 1 Nuf2 family ATG16 PF08614.6 KFM03467.1 - 0.0076 16.0 12.9 0.0076 16.0 9.0 4.1 1 1 2 3 3 3 2 Autophagy protein 16 (ATG16) Filament PF00038.16 KFM03467.1 - 0.12 11.8 50.2 2.9 7.2 17.7 3.8 1 1 2 3 3 3 0 Intermediate filament protein Mnd1 PF03962.10 KFM03467.1 - 0.81 9.3 47.2 0.54 9.8 2.6 4.3 1 1 3 4 4 4 0 Mnd1 family Reo_sigmaC PF04582.7 KFM03467.1 - 0.92 8.6 8.2 1.5 7.8 1.6 2.5 1 1 1 2 2 2 0 Reovirus sigma C capsid protein IncA PF04156.9 KFM03467.1 - 2.1 7.8 48.4 1.8 8.1 12.1 3.6 1 1 3 4 4 4 0 IncA protein Atg14 PF10186.4 KFM03467.1 - 10 4.9 52.6 89 1.8 22.9 3.9 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 PBC PF03792.8 KFM03468.1 - 4.7e-73 244.9 0.0 7.3e-73 244.3 0.0 1.2 1 0 0 1 1 1 1 PBC domain Homeobox PF00046.24 KFM03468.1 - 6.3e-20 70.5 0.9 1.5e-19 69.3 0.7 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFM03468.1 - 5.4e-16 58.0 0.0 2.9e-15 55.6 0.0 2.1 2 0 0 2 2 2 1 Homeobox KN domain HTH_3 PF01381.17 KFM03468.1 - 0.0079 16.0 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix DUF1319 PF07028.6 KFM03468.1 - 0.0082 16.3 0.4 0.018 15.2 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1319) HTH_19 PF12844.2 KFM03468.1 - 0.0087 16.0 0.1 0.024 14.6 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain Sec15 PF04091.7 KFM03468.1 - 0.011 15.1 0.2 0.017 14.4 0.2 1.3 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like Homez PF11569.3 KFM03468.1 - 0.018 14.1 0.0 0.042 12.9 0.0 1.6 1 1 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez HTH_26 PF13443.1 KFM03468.1 - 0.026 14.7 0.0 0.074 13.2 0.0 1.7 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain CENP-B_N PF04218.8 KFM03468.1 - 0.05 13.0 0.0 0.15 11.5 0.0 1.7 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain NUC130_3NT PF08158.7 KFM03468.1 - 0.3 11.4 0.9 8.4 6.7 0.0 3.2 3 1 0 3 3 3 0 NUC130/3NT domain Homeobox PF00046.24 KFM03469.1 - 5.1e-18 64.4 2.3 9.4e-18 63.5 1.6 1.5 1 0 0 1 1 1 1 Homeobox domain LIM PF00412.17 KFM03469.1 - 2.9e-16 59.2 8.2 4.8e-16 58.5 5.7 1.4 1 0 0 1 1 1 1 LIM domain Homeobox_KN PF05920.6 KFM03469.1 - 7.8e-05 22.2 0.0 0.00018 21.1 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain HTH_29 PF13551.1 KFM03469.1 - 0.66 10.1 3.9 0.61 10.2 0.4 2.1 1 1 1 2 2 2 0 Winged helix-turn helix Hormone_recep PF00104.25 KFM03470.1 - 4.7e-41 140.1 0.0 6.8e-41 139.6 0.0 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Nuc_recep-AF1 PF11825.3 KFM03470.1 - 5e-34 116.5 15.5 5e-34 116.5 10.8 1.7 2 0 0 2 2 2 1 Nuclear/hormone receptor activator site AF-1 zf-C4 PF00105.13 KFM03470.1 - 4.2e-32 110.1 15.7 7.2e-32 109.4 10.9 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Sushi PF00084.15 KFM03471.1 - 2.3e-45 152.7 71.6 5.5e-09 36.2 2.7 7.4 8 0 0 8 8 8 6 Sushi domain (SCR repeat) Lectin_C PF00059.16 KFM03471.1 - 3.1e-19 69.5 4.8 3.1e-19 69.5 3.3 2.5 3 0 0 3 3 3 1 Lectin C-type domain EGF_2 PF07974.8 KFM03471.1 - 4.8e-05 23.4 9.5 4.8e-05 23.4 6.6 5.2 4 0 0 4 4 4 1 EGF-like domain EGF PF00008.22 KFM03471.1 - 0.00045 20.1 11.1 0.00045 20.1 7.7 4.3 5 0 0 5 5 5 1 EGF-like domain DUF1968 PF09291.5 KFM03471.1 - 0.44 10.3 5.0 18 5.2 0.1 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1968) Ocnus PF05005.10 KFM03472.1 - 4.4e-32 110.1 0.3 4.9e-32 110.0 0.2 1.0 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) Methyltransf_16 PF10294.4 KFM03473.1 - 2e-12 46.9 0.0 2e-05 24.1 0.0 2.3 2 0 0 2 2 2 2 Putative methyltransferase MTS PF05175.9 KFM03473.1 - 2.1e-05 23.9 0.1 4.2e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 KFM03473.1 - 2.3e-05 24.9 0.0 4.3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFM03473.1 - 2.4e-05 23.9 0.1 0.049 13.2 0.1 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 KFM03473.1 - 7.6e-05 22.4 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KFM03473.1 - 0.00028 20.1 0.1 0.00042 19.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.7 KFM03473.1 - 0.0027 18.1 0.0 0.059 13.8 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 KFM03473.1 - 0.009 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_26 PF13659.1 KFM03473.1 - 0.053 13.5 0.0 0.16 11.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 KFM03474.1 - 3.7e-06 26.2 0.1 2.2e-05 23.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain HEAT PF02985.17 KFM03474.1 - 0.025 14.6 0.7 13 6.1 0.0 3.1 2 0 0 2 2 2 0 HEAT repeat Pkinase_Tyr PF07714.12 KFM03474.1 - 0.051 12.6 0.0 0.079 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase KAP PF05804.7 KFM03475.1 - 0 1377.4 26.4 0 1377.2 18.3 1.0 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Arm PF00514.18 KFM03475.1 - 1.3e-09 37.4 11.0 0.067 13.0 0.0 7.6 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFM03475.1 - 0.00012 22.3 0.0 2 8.7 0.0 5.0 3 2 2 5 5 5 2 HEAT repeats FPL PF09758.4 KFM03475.1 - 0.0025 17.5 2.9 0.0025 17.5 2.0 3.3 3 1 0 3 3 3 1 Uncharacterised conserved protein HEAT PF02985.17 KFM03475.1 - 0.11 12.6 1.7 11 6.3 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat Methyltransf_PK PF05891.7 KFM03476.1 - 1.5e-68 230.3 0.0 2e-68 229.9 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.2 KFM03476.1 - 0.00016 22.2 0.0 0.00028 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFM03476.1 - 0.00023 21.6 0.0 0.00035 20.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 KFM03476.1 - 0.00038 19.7 0.0 0.0006 19.0 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_12 PF08242.7 KFM03476.1 - 0.00048 20.5 0.0 0.00083 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFM03476.1 - 0.0051 17.1 0.0 0.0089 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Bystin PF05291.6 KFM03476.1 - 0.063 12.1 0.0 0.096 11.6 0.0 1.2 1 0 0 1 1 1 0 Bystin Transcrip_act PF04949.8 KFM03477.1 - 8.6e-05 22.2 14.7 0.0002 21.0 10.3 1.5 1 1 0 1 1 1 1 Transcriptional activator Homeobox PF00046.24 KFM03478.1 - 1.9e-23 81.8 6.1 3.6e-23 80.9 4.3 1.5 1 0 0 1 1 1 1 Homeobox domain OAR PF03826.12 KFM03478.1 - 2.4e-08 33.2 0.0 4.4e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.6 KFM03478.1 - 0.0013 18.3 0.1 0.003 17.2 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain FMO-like PF00743.14 KFM03479.1 - 1.3e-257 855.2 0.0 1.4e-257 855.0 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KFM03479.1 - 1e-22 81.1 0.0 1.3e-20 74.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFM03479.1 - 3.1e-11 43.5 0.0 7e-08 32.5 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFM03479.1 - 4.2e-11 42.3 0.5 3.2e-08 32.8 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KFM03479.1 - 8.6e-05 22.4 0.0 0.00024 21.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KFM03479.1 - 0.00019 21.7 0.1 0.053 13.9 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFM03479.1 - 0.00021 21.0 4.5 0.0081 15.9 0.3 3.7 2 2 1 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 KFM03479.1 - 0.001 18.2 0.1 0.045 12.8 0.0 2.4 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 KFM03479.1 - 0.0047 15.8 0.3 0.015 14.1 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 KFM03479.1 - 0.013 14.3 0.2 1.5 7.6 0.0 3.2 4 0 0 4 4 4 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 KFM03479.1 - 0.061 12.4 0.0 0.3 10.2 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KFM03479.1 - 0.082 12.4 0.1 22 4.5 0.0 3.0 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.7 KFM03479.1 - 0.17 11.2 0.0 3.1 7.1 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain GIDA PF01134.17 KFM03479.1 - 0.22 10.3 0.0 16 4.1 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A FMO-like PF00743.14 KFM03480.1 - 3.1e-237 787.9 0.0 3.5e-237 787.8 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KFM03480.1 - 1.8e-16 60.8 0.0 2e-15 57.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFM03480.1 - 1.1e-07 31.9 0.0 7.3e-06 26.0 0.0 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFM03480.1 - 1.4e-06 27.4 0.2 3.3e-05 22.9 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KFM03480.1 - 8.2e-06 25.6 0.0 6.2e-05 22.8 0.0 2.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KFM03480.1 - 3.1e-05 23.9 0.0 7.6e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KFM03480.1 - 0.015 15.6 0.3 4.2 7.8 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 KFM03480.1 - 0.18 10.9 0.0 0.48 9.5 0.0 1.7 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain OLF PF02191.11 KFM03481.1 - 7.7e-87 290.7 0.0 8.8e-87 290.5 0.0 1.0 1 0 0 1 1 1 1 Olfactomedin-like domain Synaptobrevin PF00957.16 KFM03482.1 - 5.3e-35 118.9 2.9 7e-35 118.4 2.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Fzo_mitofusin PF04799.8 KFM03482.1 - 0.027 13.8 0.9 0.039 13.3 0.6 1.2 1 0 0 1 1 1 0 fzo-like conserved region DUF1035 PF06281.7 KFM03482.1 - 0.028 14.2 0.1 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1035) NPV_P10 PF05531.7 KFM03482.1 - 0.038 14.2 0.2 0.065 13.4 0.2 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein L31 PF09784.4 KFM03482.1 - 0.072 13.1 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 UPF0258 PF06789.7 KFM03482.1 - 0.14 12.1 0.8 0.23 11.4 0.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) Ham1p_like PF01725.11 KFM03483.1 - 2.3e-47 160.8 0.0 2.6e-47 160.6 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Methyltransf_31 PF13847.1 KFM03484.1 - 1.2e-17 63.9 0.0 1.6e-10 40.7 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 KFM03484.1 - 2e-17 63.4 0.1 7.3e-12 45.6 0.0 3.4 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 KFM03484.1 - 3.5e-16 59.7 0.0 1.8e-06 28.5 0.0 3.0 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_25 PF13649.1 KFM03484.1 - 4.2e-09 36.6 0.0 3.8e-05 23.9 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Spermine_synth PF01564.12 KFM03484.1 - 1.7e-08 33.7 0.6 1.4e-07 30.7 0.0 2.2 2 0 0 2 2 2 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 KFM03484.1 - 1.3e-07 31.6 0.0 6.9e-06 26.0 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFM03484.1 - 3.7e-06 27.3 0.0 0.0048 17.3 0.0 2.9 2 1 0 2 2 2 2 Methyltransferase domain MTS PF05175.9 KFM03484.1 - 5.3e-05 22.6 0.0 0.25 10.7 0.0 2.5 2 1 0 2 2 2 2 Methyltransferase small domain Methyltransf_23 PF13489.1 KFM03484.1 - 0.00015 21.5 0.0 0.031 13.9 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFM03484.1 - 0.0013 17.8 0.1 0.0067 15.5 0.1 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Dynamin_M PF01031.15 KFM03485.1 - 2.6e-97 325.1 4.4 2.6e-97 325.1 3.1 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 KFM03485.1 - 7.7e-43 146.2 0.0 2.2e-42 144.6 0.0 1.9 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KFM03485.1 - 1.3e-25 89.1 4.7 1.3e-25 89.1 3.3 2.7 3 0 0 3 3 3 1 Dynamin GTPase effector domain PH PF00169.24 KFM03485.1 - 1.7e-10 41.0 0.7 3.7e-10 39.9 0.5 1.5 1 0 0 1 1 1 1 PH domain GPI2 PF06432.6 KFM03486.1 - 1.3e-75 254.4 9.2 1.4e-75 254.2 6.4 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Sad1_UNC PF07738.8 KFM03487.1 - 3.9e-39 133.5 0.0 1e-38 132.1 0.0 1.8 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Tox-SHH PF15652.1 KFM03487.1 - 0.026 15.0 0.3 3.7 8.2 0.0 3.7 2 1 1 3 3 3 0 HNH/Endo VII superfamily toxin with a SHH signature Tweety PF04906.8 KFM03487.1 - 0.055 11.8 4.9 0.092 11.1 3.4 1.2 1 0 0 1 1 1 0 Tweety MbeD_MobD PF04899.7 KFM03487.1 - 0.26 11.2 9.8 0.098 12.5 4.5 2.0 2 0 0 2 2 2 0 MbeD/MobD like SlyX PF04102.7 KFM03487.1 - 1.8 8.9 11.7 2.5 8.5 2.2 2.9 1 1 1 2 2 2 0 SlyX Baculo_PEP_C PF04513.7 KFM03487.1 - 5.2 6.8 13.6 0.087 12.6 4.3 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TNF PF00229.13 KFM03488.1 - 8.7e-32 109.3 0.5 1.2e-31 108.8 0.3 1.2 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family Cytochrom_B_N PF00033.14 KFM03488.1 - 0.033 13.5 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Ni_hydr_CYTB PF01292.15 KFM03488.1 - 0.072 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 TNF PF00229.13 KFM03489.1 - 0.0069 15.9 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family SAGA-Tad1 PF12767.2 KFM03490.1 - 1e-41 143.2 1.7 4.2e-40 137.9 1.2 2.2 1 1 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.9 KFM03490.1 - 0.028 13.7 0.0 0.063 12.5 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family AhpC-TSA PF00578.16 KFM03491.1 - 4.2e-14 52.2 0.0 7.7e-14 51.4 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 KFM03491.1 - 7.4e-14 51.1 0.4 1.2e-13 50.3 0.3 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 KFM03491.1 - 0.00027 20.5 0.0 0.00045 19.7 0.0 1.3 1 0 0 1 1 1 1 Redoxin PAM2 PF07145.10 KFM03491.1 - 0.043 13.3 0.4 0.22 11.0 0.0 2.2 2 0 0 2 2 2 0 Ataxin-2 C-terminal region RFC1 PF08519.7 KFM03492.1 - 0.0059 16.3 0.1 0.0081 15.9 0.1 1.2 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain PAP2 PF01569.16 KFM03493.1 - 4.7e-22 78.0 5.6 8e-22 77.3 3.9 1.3 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 KFM03493.1 - 0.00093 19.4 3.1 0.00093 19.4 2.2 2.0 1 1 1 2 2 2 1 PAP2 superfamily C-terminal PAP2_3 PF14378.1 KFM03493.1 - 0.051 13.0 7.2 0.027 13.9 3.6 1.6 2 0 0 2 2 2 0 PAP2 superfamily FMO-like PF00743.14 KFM03494.1 - 8.5e-254 842.6 0.0 9.5e-254 842.4 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KFM03494.1 - 2.2e-18 67.0 0.0 2.6e-17 63.5 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFM03494.1 - 1.8e-10 40.2 0.1 1e-07 31.2 0.0 3.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KFM03494.1 - 1.3e-09 38.2 0.0 8.7e-08 32.2 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFM03494.1 - 4e-06 26.6 1.8 0.0018 18.0 0.2 3.6 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KFM03494.1 - 3.6e-05 23.6 0.0 0.00014 21.8 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KFM03494.1 - 0.0003 19.9 0.2 0.087 11.8 0.0 2.3 2 0 0 2 2 2 2 Thi4 family Pyr_redox PF00070.22 KFM03494.1 - 0.017 15.5 0.8 0.6 10.5 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFM03494.1 - 0.026 13.0 1.1 0.34 9.3 0.2 2.3 2 0 0 2 2 2 0 HI0933-like protein DAO PF01266.19 KFM03494.1 - 0.034 13.0 1.1 1.1 8.0 0.1 2.5 1 1 1 3 3 3 0 FAD dependent oxidoreductase GIDA PF01134.17 KFM03494.1 - 0.045 12.5 0.0 2.6 6.7 0.0 2.8 3 0 0 3 3 3 0 Glucose inhibited division protein A IlvN PF07991.7 KFM03494.1 - 0.1 11.9 0.0 3 7.1 0.0 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_Gly3P_dh_N PF01210.18 KFM03494.1 - 0.17 11.5 0.3 4.3 7.0 0.0 2.5 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FMO-like PF00743.14 KFM03495.1 - 5e-250 830.2 0.0 5.6e-250 830.0 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KFM03495.1 - 2e-18 67.1 0.0 8.1e-18 65.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFM03495.1 - 5.2e-09 35.4 0.3 7e-07 28.4 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KFM03495.1 - 5.1e-07 29.7 0.0 3.3e-05 23.8 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFM03495.1 - 1.2e-06 28.4 1.6 0.00077 19.2 0.1 3.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KFM03495.1 - 1.4e-05 24.9 0.1 0.00013 21.8 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KFM03495.1 - 0.00047 20.5 2.1 0.015 15.6 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFM03495.1 - 0.0036 16.4 0.1 2.5 7.1 0.0 2.3 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.9 KFM03495.1 - 0.28 9.6 0.6 15 3.8 0.1 2.4 2 0 0 2 2 2 0 HI0933-like protein DAO PF01266.19 KFM03495.1 - 0.39 9.5 4.8 3 6.6 0.3 2.7 1 1 0 2 2 2 0 FAD dependent oxidoreductase AMPKBI PF04739.10 KFM03496.1 - 4.4e-30 103.5 0.2 6.7e-30 102.9 0.1 1.3 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interation domain CBM_48 PF02922.13 KFM03496.1 - 0.13 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Prok-JAB PF14464.1 KFM03498.1 - 0.054 13.0 0.1 0.94 9.0 0.0 2.1 2 0 0 2 2 2 0 Prokaryotic homologs of the JAB domain DUF4164 PF13747.1 KFM03498.1 - 0.081 13.0 9.0 0.27 11.3 0.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Lzipper-MIP1 PF14389.1 KFM03498.1 - 1.1 9.3 6.6 3.1 7.9 0.3 2.9 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 CENP-F_leu_zip PF10473.4 KFM03498.1 - 8.6 6.2 9.1 12 5.7 0.7 2.2 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-AD PF07776.10 KFM03499.1 - 0.00021 21.2 2.1 0.00021 21.2 1.4 3.8 3 1 0 3 3 3 1 Zinc-finger associated domain (zf-AD) Reo_sigmaC PF04582.7 KFM03499.1 - 0.00046 19.4 17.4 0.00064 19.0 1.6 3.2 1 1 2 3 3 3 2 Reovirus sigma C capsid protein ATG16 PF08614.6 KFM03499.1 - 0.0026 17.6 10.7 0.0026 17.6 7.4 5.8 2 1 2 4 4 4 1 Autophagy protein 16 (ATG16) 2-Hacid_dh_C PF02826.14 KFM03500.1 - 9.4e-59 197.5 0.0 1.5e-58 196.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFM03500.1 - 1.8e-19 69.4 0.0 2.7e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain HMG_CoA_synt_C PF08540.5 KFM03501.1 - 9.4e-124 412.4 0.0 1.2e-123 412.1 0.0 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KFM03501.1 - 4.5e-99 329.1 0.1 6e-99 328.7 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III PF08545.5 KFM03501.1 - 0.0018 17.8 0.3 0.0039 16.8 0.2 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Lectin_C PF00059.16 KFM03502.1 - 3.3e-14 53.4 0.9 4e-14 53.1 0.6 1.1 1 0 0 1 1 1 1 Lectin C-type domain Ank PF00023.25 KFM03503.1 - 2.2e-40 134.4 14.6 6.6e-09 35.1 0.0 7.2 7 0 0 7 7 7 6 Ankyrin repeat Ank_2 PF12796.2 KFM03503.1 - 8.5e-34 115.7 7.5 5e-13 49.2 0.2 4.4 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFM03503.1 - 2.2e-26 91.2 12.2 6.4e-10 38.9 0.7 5.8 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Notch PF00066.12 KFM03503.1 - 4.1e-25 87.7 77.4 1.5e-11 44.3 11.3 5.7 4 1 0 4 4 3 3 LNR domain NOD PF06816.8 KFM03503.1 - 6.6e-24 82.7 0.0 1.1e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 NOTCH protein DUF3454 PF11936.3 KFM03503.1 - 1.2e-23 83.1 22.1 1.2e-23 83.1 15.3 2.6 2 1 0 2 2 1 1 Domain of unknown function (DUF3454) NODP PF07684.7 KFM03503.1 - 6.9e-22 76.8 3.4 2.8e-21 74.8 0.0 3.2 2 0 0 2 2 2 1 NOTCH protein Ank_3 PF13606.1 KFM03503.1 - 4.2e-21 72.9 4.3 0.00019 21.3 0.1 6.7 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 KFM03503.1 - 2.8e-18 65.8 5.8 5.3e-08 33.1 0.4 4.5 3 2 2 5 5 5 4 Ankyrin repeats (many copies) EGF PF00008.22 KFM03503.1 - 4.2e-09 36.1 20.5 5.7e-06 26.1 3.9 7.3 8 0 0 8 8 5 4 EGF-like domain hEGF PF12661.2 KFM03503.1 - 2.2e-05 24.2 36.9 0.0012 18.7 2.2 5.6 6 0 0 6 6 6 3 Human growth factor-like EGF EGF_2 PF07974.8 KFM03503.1 - 0.0021 18.2 8.3 0.0021 18.2 5.8 8.7 7 1 1 8 8 5 3 EGF-like domain EGF_CA PF07645.10 KFM03503.1 - 0.0068 16.3 5.8 0.0068 16.3 4.0 7.3 4 1 3 7 7 3 2 Calcium-binding EGF domain Glyco_transf_29 PF00777.13 KFM03505.1 - 5.4e-63 212.6 0.1 8.5e-63 211.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) 7tm_1 PF00001.16 KFM03506.1 - 3.2e-23 82.2 12.0 3.9e-23 81.9 8.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM03506.1 - 0.00027 20.1 6.6 0.00035 19.8 4.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Str PF10326.4 KFM03506.1 - 0.041 13.0 11.7 0.04 13.0 6.5 2.0 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Str DUF1109 PF06532.6 KFM03506.1 - 0.056 12.8 2.9 0.034 13.5 1.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1109) Phage_Gp23 PF10669.4 KFM03506.1 - 5.9 7.0 6.0 21 5.2 0.1 2.4 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) 7tm_1 PF00001.16 KFM03507.1 - 1.9e-32 112.3 23.7 2.3e-32 112.1 16.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM03507.1 - 0.00017 20.8 22.0 0.00021 20.5 15.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.16 KFM03508.1 - 4.6e-38 130.8 18.3 5.5e-38 130.5 12.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.16 KFM03509.1 - 8.7e-37 126.6 20.8 1e-36 126.4 14.4 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 60KD_IMP PF02096.15 KFM03509.1 - 0.44 10.1 5.3 0.052 13.2 0.3 1.8 2 0 0 2 2 2 0 60Kd inner membrane protein BRICHOS PF04089.9 KFM03510.1 - 6.1e-30 102.9 0.0 8.7e-30 102.4 0.0 1.2 1 0 0 1 1 1 1 BRICHOS domain Mo25 PF08569.6 KFM03511.1 - 4.6e-145 482.8 14.7 5.2e-145 482.6 10.2 1.0 1 0 0 1 1 1 1 Mo25-like HEAT_2 PF13646.1 KFM03511.1 - 0.11 12.7 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 HEAT repeats HLH PF00010.21 KFM03512.1 - 2.2e-14 52.8 1.6 4.3e-14 51.9 1.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.8 KFM03512.1 - 4.7e-14 51.8 0.1 9.8e-14 50.8 0.1 1.6 1 0 0 1 1 1 1 Hairy Orange Period_C PF12114.3 KFM03513.1 - 1e-79 266.7 5.1 1e-79 266.7 3.6 4.3 4 1 1 5 5 5 1 Period protein 2/3C-terminal region PAS_11 PF14598.1 KFM03513.1 - 1.2e-11 44.5 0.0 4.3e-11 42.7 0.0 2.0 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.6 KFM03513.1 - 2e-09 37.4 0.0 4.9e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 KFM03513.1 - 6.5e-06 25.9 0.0 0.00027 20.7 0.0 2.6 2 0 0 2 2 2 1 PAS fold Synaptobrevin PF00957.16 KFM03514.1 - 3.2e-22 77.9 1.0 3.4e-22 77.8 0.7 1.0 1 0 0 1 1 1 1 Synaptobrevin Seryl_tRNA_N PF02403.17 KFM03514.1 - 0.031 14.2 0.2 0.035 14.1 0.1 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain PI3Ka PF00613.15 KFM03516.1 - 6.9e-62 207.9 1.3 1.5e-61 206.8 0.9 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 KFM03516.1 - 7.1e-58 195.8 0.0 1.2e-57 195.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_p85B PF02192.11 KFM03516.1 - 5.8e-37 124.9 0.1 3.4e-36 122.4 0.0 2.3 2 0 0 2 2 2 1 PI3-kinase family, p85-binding domain PI3K_rbd PF00794.13 KFM03516.1 - 4.3e-31 107.0 0.1 1e-30 105.8 0.0 1.7 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.19 KFM03516.1 - 5.6e-25 87.7 0.0 1.1e-24 86.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Fork_head PF00250.13 KFM03517.1 - 1.4e-41 140.4 0.1 2e-41 139.9 0.1 1.2 1 0 0 1 1 1 1 Fork head domain Coatomer_WDAD PF04053.9 KFM03518.1 - 1.7e-165 551.1 0.0 2.9e-165 550.3 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.27 KFM03518.1 - 4.3e-56 184.8 5.7 4.3e-13 48.5 0.1 7.2 6 0 0 6 6 6 6 WD domain, G-beta repeat Lipocalin PF00061.18 KFM03519.1 - 2.9e-18 66.2 5.1 3.2e-18 66.1 3.5 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.1 KFM03519.1 - 2.3e-08 33.8 0.6 2.6e-08 33.6 0.4 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family DNA_pol3_delta PF06144.8 KFM03519.1 - 0.1 12.1 0.5 0.15 11.5 0.1 1.4 2 0 0 2 2 2 0 DNA polymerase III, delta subunit Lipocalin PF00061.18 KFM03520.1 - 5.1e-18 65.4 0.3 6.1e-18 65.1 0.2 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.1 KFM03520.1 - 2.1e-05 24.2 0.2 2.6e-05 23.9 0.1 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family CTP_transf_2 PF01467.21 KFM03521.1 - 4.7e-13 49.4 0.0 6.5e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase CTP_transf_2 PF01467.21 KFM03522.1 - 7.8e-40 136.4 0.0 1.8e-39 135.3 0.0 1.6 1 1 0 1 1 1 1 Cytidylyltransferase Cadherin PF00028.12 KFM03523.1 - 1.6e-15 57.1 0.2 9.8e-10 38.5 0.5 2.7 2 0 0 2 2 2 2 Cadherin domain Laminin_G_3 PF13385.1 KFM03523.1 - 1.4e-08 35.0 0.0 2.7e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF1510 PF07423.6 KFM03523.1 - 0.0011 18.4 16.1 0.0017 17.7 11.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Glyco_hydro_16 PF00722.16 KFM03523.1 - 0.005 16.1 0.6 0.026 13.7 0.3 2.3 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 Ycf1 PF05758.7 KFM03523.1 - 0.013 13.3 4.0 0.019 12.7 2.8 1.1 1 0 0 1 1 1 0 Ycf1 IncA PF04156.9 KFM03523.1 - 0.11 12.0 1.0 0.22 11.0 0.7 1.4 1 0 0 1 1 1 0 IncA protein fn3 PF00041.16 KFM03524.1 - 2.5e-08 33.9 0.1 4.8e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain zf-B_box PF00643.19 KFM03524.1 - 6.6e-08 32.3 19.6 3.2e-07 30.1 3.3 7.4 6 1 1 7 7 7 3 B-box zinc finger SPRY PF00622.23 KFM03525.1 - 9.5e-19 67.7 0.0 1.4e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 SPRY domain SOCS_box PF07525.11 KFM03525.1 - 1.8e-13 50.1 3.9 3.4e-13 49.2 2.7 1.5 1 0 0 1 1 1 1 SOCS box His_Phos_2 PF00328.17 KFM03526.1 - 7e-42 143.9 0.1 8.2e-42 143.7 0.1 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Ribosomal_60s PF00428.14 KFM03527.1 - 6.5 7.2 7.3 9.3 6.7 5.1 1.4 1 1 0 1 1 1 0 60s Acidic ribosomal protein TFIIB PF00382.14 KFM03528.1 - 4.7e-33 112.8 0.0 1.1e-15 57.1 0.0 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 KFM03528.1 - 2.1e-26 91.9 11.9 2.1e-26 91.9 8.3 2.9 3 0 0 3 3 3 1 Brf1-like TBP-binding domain Cyclin_N PF00134.18 KFM03528.1 - 1.4e-08 34.3 0.3 0.00023 20.7 0.1 2.6 2 0 0 2 2 2 2 Cyclin, N-terminal domain PHR PF08005.7 KFM03529.1 - 1.6e-46 158.2 0.9 2.7e-46 157.4 0.6 1.4 1 0 0 1 1 1 1 PHR domain BTB PF00651.26 KFM03529.1 - 9.3e-25 86.7 0.1 9.9e-24 83.4 0.0 2.3 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.10 KFM03529.1 - 3.8e-07 29.8 3.0 7.9e-07 28.8 0.7 2.5 2 1 0 2 2 2 1 BTB And C-terminal Kelch PPPI_inhib PF14895.1 KFM03530.1 - 1.1e-39 136.1 0.2 1.4e-39 135.8 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 1 inhibitor HSP70 PF00012.15 KFM03531.1 - 2.3e-275 914.2 11.4 2.6e-275 914.0 7.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFM03531.1 - 2e-17 62.7 0.7 7.7e-16 57.5 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 KFM03531.1 - 0.00011 21.9 0.7 0.065 13.0 0.0 3.6 2 2 0 2 2 2 1 Cell division protein FtsA FGGY_C PF02782.11 KFM03531.1 - 0.00025 20.7 0.0 0.00062 19.4 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 KFM03531.1 - 0.002 17.2 2.2 0.019 14.0 0.1 2.9 2 1 1 3 3 3 1 Hydantoinase/oxoprolinase DDR PF08841.5 KFM03531.1 - 0.018 13.8 0.4 0.17 10.6 0.1 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain BTB PF00651.26 KFM03532.1 - 1.2e-19 70.3 1.5 1.2e-19 70.3 1.1 1.9 2 0 0 2 2 2 1 BTB/POZ domain zf-C2H2_4 PF13894.1 KFM03532.1 - 4.3e-14 51.7 61.5 0.0015 18.7 0.1 10.5 10 1 0 10 10 10 7 C2H2-type zinc finger zf-C2H2 PF00096.21 KFM03532.1 - 5.6e-09 35.8 67.8 0.012 15.8 0.2 10.5 9 1 1 10 10 10 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM03532.1 - 1.1e-07 31.7 50.8 0.00026 21.1 2.3 9.4 9 1 0 9 9 9 5 Zinc-finger double domain zf-met PF12874.2 KFM03532.1 - 0.0021 18.1 42.4 0.095 12.9 0.3 9.1 8 0 0 8 8 8 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFM03532.1 - 0.0081 16.2 0.2 0.0081 16.2 0.2 8.7 8 0 0 8 8 8 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFM03532.1 - 0.7 9.8 0.0 0.54 10.2 0.1 8.2 8 0 0 8 8 8 0 C2H2-type zinc finger zf-Di19 PF05605.7 KFM03532.1 - 7.2 6.8 47.7 0.14 12.2 2.0 7.4 4 2 5 9 9 9 0 Drought induced 19 protein (Di19), zinc-binding BTB PF00651.26 KFM03533.1 - 1.4e-20 73.2 0.3 3.4e-20 72.0 0.1 1.7 2 0 0 2 2 2 1 BTB/POZ domain zf-C2H2 PF00096.21 KFM03533.1 - 1.4e-07 31.3 15.9 0.00018 21.6 0.7 4.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM03533.1 - 5.9e-06 26.2 13.5 0.0034 17.6 0.5 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM03533.1 - 2.1e-05 24.5 7.2 0.015 15.4 1.2 2.9 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFM03533.1 - 0.0002 21.3 3.9 0.18 11.9 0.8 2.6 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 KFM03533.1 - 0.0041 16.7 1.5 0.21 11.3 0.1 2.7 2 0 0 2 2 2 1 zinc-finger of a C2HC-type PyrI_C PF02748.10 KFM03533.1 - 0.056 12.8 1.2 11 5.5 0.0 2.6 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-Di19 PF05605.7 KFM03533.1 - 0.15 12.1 7.1 0.89 9.7 0.4 3.0 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 KFM03533.1 - 0.47 10.7 5.0 0.18 12.0 0.4 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type FYVE PF01363.16 KFM03533.1 - 0.81 9.6 7.0 2.5 8.0 2.1 2.4 2 0 0 2 2 2 0 FYVE zinc finger Zn_ribbon_recom PF13408.1 KFM03533.1 - 2.7 8.2 6.1 0.83 9.9 0.9 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain FTHFS PF01268.14 KFM03535.1 - 8e-260 862.5 0.1 1e-259 862.2 0.1 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 KFM03535.1 - 2.9e-67 224.7 1.3 2.9e-67 224.7 0.9 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 KFM03535.1 - 1e-32 112.5 0.1 4.8e-32 110.4 0.1 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain ERbeta_N PF12497.3 KFM03536.1 - 3.9e-36 123.2 9.2 7.4e-36 122.3 6.3 1.5 1 0 0 1 1 1 1 Estrogen receptor beta Hormone_recep PF00104.25 KFM03536.1 - 2.4e-34 118.2 0.7 4e-34 117.5 0.5 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFM03536.1 - 1.4e-31 108.4 13.3 3e-31 107.4 9.2 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) PAP2 PF01569.16 KFM03537.1 - 5.2e-18 64.9 6.3 5.2e-18 64.9 4.4 1.8 2 0 0 2 2 2 1 PAP2 superfamily DUF202 PF02656.10 KFM03537.1 - 3.9 7.7 6.3 7.6 6.8 0.8 3.6 2 2 0 2 2 2 0 Domain of unknown function (DUF202) WD40 PF00400.27 KFM03538.1 - 1.5e-18 65.8 10.0 1.7e-05 24.5 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat B56 PF01603.15 KFM03539.1 - 1.4e-169 564.0 10.0 1.6e-169 563.8 6.9 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.2 KFM03539.1 - 0.062 12.7 4.7 1.1 8.6 0.3 3.2 3 1 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Cys_knot PF00007.17 KFM03540.1 - 1.3e-17 63.8 7.6 1.5e-17 63.5 5.2 1.1 1 0 0 1 1 1 1 Cystine-knot domain DAN PF03045.10 KFM03540.1 - 0.0092 15.3 1.9 0.015 14.6 1.3 1.4 1 1 0 1 1 1 1 DAN domain Ras PF00071.17 KFM03541.1 - 1.4e-48 164.3 0.0 1.7e-48 164.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM03541.1 - 4.3e-17 62.7 0.0 6.2e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM03541.1 - 2.1e-05 23.8 0.0 3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MobB PF03205.9 KFM03541.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SERTA PF06031.8 KFM03542.1 - 3.1e-14 51.9 1.6 4.5e-14 51.4 1.1 1.3 1 0 0 1 1 1 1 SERTA motif ADP_ribosyl_GH PF03747.9 KFM03543.1 - 1.8e-20 73.9 1.3 7e-19 68.6 0.1 2.2 2 0 0 2 2 2 2 ADP-ribosylglycohydrolase AIF_C PF14721.1 KFM03544.1 - 3.7e-60 201.9 0.0 9.7e-60 200.6 0.0 1.7 2 0 0 2 2 2 1 Apoptosis-inducing factor, mitochondrion-associated, C-term Pyr_redox_2 PF07992.9 KFM03544.1 - 4.8e-21 75.5 0.0 1.1e-20 74.3 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AIF-MLS PF14962.1 KFM03544.1 - 4.8e-15 55.6 0.1 4.8e-15 55.6 0.0 1.7 2 0 0 2 2 2 1 Mitochondria Localisation Sequence Pyr_redox PF00070.22 KFM03544.1 - 1.6e-11 44.3 0.1 4.5e-10 39.7 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFM03544.1 - 6.9e-06 25.9 1.9 0.57 9.9 0.0 4.3 3 1 1 4 4 4 2 FAD-NAD(P)-binding DAO PF01266.19 KFM03544.1 - 7.4e-06 25.0 5.9 0.011 14.6 0.0 3.9 4 0 0 4 4 4 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KFM03544.1 - 5.3e-05 23.3 0.0 0.26 11.2 0.0 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KFM03544.1 - 0.00086 18.3 0.3 0.074 11.9 0.0 3.0 2 1 0 3 3 3 1 Lycopene cyclase protein HI0933_like PF03486.9 KFM03544.1 - 0.0041 15.6 0.2 1.2 7.5 0.0 3.1 3 0 0 3 3 3 1 HI0933-like protein K_oxygenase PF13434.1 KFM03544.1 - 0.034 13.0 0.0 0.28 10.0 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KFM03544.1 - 0.044 13.8 1.1 9.5 6.3 0.1 2.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Reductase_C PF14759.1 KFM03544.1 - 0.09 13.0 0.0 0.32 11.3 0.0 1.9 1 0 0 1 1 1 0 Reductase C-terminal FAD_oxidored PF12831.2 KFM03544.1 - 0.11 11.5 1.0 0.64 9.0 0.1 2.3 3 0 0 3 3 3 0 FAD dependent oxidoreductase tRNA-synt_1g PF09334.6 KFM03545.1 - 2.2e-97 326.2 0.0 2.9e-97 325.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KFM03545.1 - 3.9e-13 48.2 0.0 2.4e-10 39.0 0.0 3.0 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KFM03545.1 - 1.7e-05 24.6 0.0 2.7e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 KFM03545.1 - 4.5e-05 22.7 0.0 6.7e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Mito_carr PF00153.22 KFM03547.1 - 1e-48 162.9 0.2 4.1e-22 77.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ThiW PF09512.5 KFM03547.1 - 0.027 14.2 1.4 0.046 13.5 0.9 1.5 1 1 0 1 1 1 0 Thiamine-precursor transporter protein (ThiW) 7tm_1 PF00001.16 KFM03548.1 - 1.1e-40 139.4 11.6 1.3e-40 139.1 8.1 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) NAD4L PF06235.6 KFM03548.1 - 0.13 12.0 0.3 0.13 12.0 0.2 2.4 2 0 0 2 2 2 0 NADH dehydrogenase subunit 4L (NAD4L) RRM_1 PF00076.17 KFM03549.1 - 1.8e-08 33.8 0.1 4.2e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM03549.1 - 8.4e-06 25.6 0.0 1.8e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFM03549.1 - 0.012 15.3 0.1 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.1 KFM03549.1 - 0.022 14.5 0.1 0.054 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF464 PF04327.7 KFM03549.1 - 0.78 10.0 3.9 15 5.9 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF464) RhoGAP PF00620.22 KFM03550.1 - 5.5e-47 159.1 0.0 6.1e-46 155.7 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain RGCC PF15151.1 KFM03551.1 - 2.7e-43 147.2 0.1 3.1e-43 147.0 0.1 1.0 1 0 0 1 1 1 1 Response gene to complement 32 protein family Voltage_CLC PF00654.15 KFM03552.1 - 1.5e-102 343.2 21.5 1.5e-102 343.2 14.9 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 KFM03552.1 - 3.6e-16 58.6 2.2 2e-08 33.8 0.0 2.4 2 0 0 2 2 2 2 CBS domain TNF PF00229.13 KFM03553.1 - 1.1e-35 121.9 0.1 1.7e-35 121.3 0.0 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family V-set PF07686.12 KFM03554.1 - 9.4e-14 51.2 0.5 9.9e-09 35.0 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin V-set domain I-set PF07679.11 KFM03554.1 - 5.6e-12 45.3 0.0 2.3e-09 36.9 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM03554.1 - 3.5e-09 36.6 0.9 8.6e-06 25.7 0.1 2.2 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 KFM03554.1 - 0.00069 19.6 1.5 0.051 13.7 0.2 2.8 2 1 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.1 KFM03554.1 - 0.00082 19.8 3.1 0.0015 18.9 1.4 2.0 2 1 0 2 2 2 1 Immunoglobulin domain I-set PF07679.11 KFM03555.1 - 2.7e-13 49.5 0.0 2.9e-09 36.6 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.12 KFM03555.1 - 1.8e-10 40.6 0.1 1.6e-06 28.0 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.1 KFM03555.1 - 1.7e-08 34.4 0.1 1.8e-05 24.7 0.0 2.3 2 1 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 KFM03555.1 - 5.7e-08 33.1 0.2 8.8e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 KFM03555.1 - 3.9e-05 23.6 0.0 0.048 13.7 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin domain Herpes_gE PF02480.11 KFM03555.1 - 0.0058 14.9 0.0 0.014 13.7 0.0 1.6 1 1 1 2 2 2 1 Alphaherpesvirus glycoprotein E SEEK1 PF15357.1 KFM03555.1 - 0.0096 15.8 0.0 0.024 14.5 0.0 1.8 1 1 0 1 1 1 1 Psoriasis susceptibility 1 candidate 1 V-set PF07686.12 KFM03556.1 - 2e-06 27.6 0.0 1e-05 25.3 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.1 KFM03556.1 - 0.0033 17.8 0.3 0.088 13.3 0.2 2.7 1 1 0 1 1 1 1 Immunoglobulin domain TauD PF02668.11 KFM03557.1 - 1.6e-37 129.6 0.2 2.7e-37 128.8 0.1 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 KFM03557.1 - 2e-05 24.9 0.0 4.8e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.5 KFM03557.1 - 0.003 16.5 0.0 0.011 14.7 0.0 1.7 2 0 0 2 2 2 1 CsiD Pou PF00157.12 KFM03558.1 - 1.3e-31 108.1 0.0 2.2e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.24 KFM03558.1 - 7.5e-18 63.8 1.7 1.8e-17 62.7 1.2 1.6 1 0 0 1 1 1 1 Homeobox domain HTH_31 PF13560.1 KFM03558.1 - 0.00025 21.1 0.2 0.0094 16.1 0.0 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_19 PF12844.2 KFM03558.1 - 0.00083 19.3 0.0 0.049 13.6 0.0 2.3 2 1 0 2 2 2 1 Helix-turn-helix domain Homeobox_KN PF05920.6 KFM03558.1 - 0.027 14.1 0.0 0.063 12.9 0.0 1.6 1 0 0 1 1 1 0 Homeobox KN domain Lsr2 PF11774.3 KFM03558.1 - 0.12 12.2 0.2 0.2 11.6 0.1 1.4 1 1 0 1 1 1 0 Lsr2 7tm_1 PF00001.16 KFM03559.1 - 4.4e-37 127.6 14.5 6.7e-37 127.0 10.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM03559.1 - 0.00016 20.9 13.2 0.0017 17.5 9.1 2.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM03559.1 - 0.0018 17.4 6.2 0.0029 16.7 4.1 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx RNA_pol_L_2 PF13656.1 KFM03560.1 - 7.3e-30 102.2 0.0 8.4e-30 102.0 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KFM03560.1 - 3.1e-11 42.2 0.0 3.7e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DuffyBP_N PF12377.3 KFM03560.1 - 0.14 12.4 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Duffy binding protein N terminal Synaptobrevin PF00957.16 KFM03561.1 - 2.9e-28 97.3 2.8 4.4e-28 96.7 1.9 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 KFM03561.1 - 2.9e-28 97.2 0.5 4.9e-28 96.5 0.4 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF3753 PF12575.3 KFM03561.1 - 0.71 9.7 11.1 1.3 8.8 2.6 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3753) SLAIN PF15301.1 KFM03562.1 - 1.2e-109 366.9 52.6 3.9e-109 365.2 36.5 1.7 1 1 0 1 1 1 1 SLAIN motif-containing family DUF4095 PF13338.1 KFM03562.1 - 0.0057 16.7 0.1 3.9 7.6 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4095) LIM PF00412.17 KFM03563.1 - 0.011 15.7 16.7 0.017 15.1 11.5 1.3 1 0 0 1 1 1 0 LIM domain Endonuclease_7 PF02945.10 KFM03563.1 - 0.19 11.4 10.1 0.3 10.8 7.0 1.3 1 0 0 1 1 1 0 Recombination endonuclease VII 3Beta_HSD PF01073.14 KFM03564.1 - 9e-71 237.8 0.0 1.1e-70 237.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KFM03564.1 - 5.4e-38 130.7 0.0 6.8e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFM03564.1 - 6.5e-17 62.1 0.0 9.6e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KFM03564.1 - 4.9e-16 58.4 0.0 6.9e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KFM03564.1 - 3.1e-12 45.9 0.0 8.3e-08 31.4 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein NmrA PF05368.8 KFM03564.1 - 2.3e-08 33.6 0.0 3.6e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 KFM03564.1 - 1.7e-07 30.4 0.0 1.2e-06 27.6 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KFM03564.1 - 0.0017 18.3 0.2 0.43 10.4 0.1 2.2 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_2 PF03446.10 KFM03564.1 - 0.011 15.5 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase KR PF08659.5 KFM03564.1 - 0.1 12.2 0.2 3.1 7.4 0.0 2.2 1 1 1 2 2 2 0 KR domain EF-hand_1 PF00036.27 KFM03565.1 - 3.5e-31 104.1 17.8 9.8e-09 33.9 0.5 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KFM03565.1 - 4.5e-27 93.9 9.5 2.2e-14 53.3 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KFM03565.1 - 2.2e-26 91.1 16.1 1.5e-12 46.9 0.6 3.9 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 KFM03565.1 - 2.2e-24 83.1 11.2 2.6e-08 33.0 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KFM03565.1 - 3.2e-17 61.0 18.2 2.3e-05 23.5 0.2 4.6 4 1 1 5 5 5 4 EF hand EF-hand_9 PF14658.1 KFM03565.1 - 1.2e-15 57.1 0.1 1.5e-06 27.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KFM03565.1 - 1.3e-07 31.2 6.4 0.021 14.5 0.0 3.2 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand DUF853 PF05872.7 KFM03565.1 - 0.0031 15.9 0.5 0.012 14.0 0.2 1.7 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF853) DUF4373 PF14297.1 KFM03565.1 - 0.032 14.5 3.2 2.5 8.4 0.2 3.3 1 1 3 4 4 4 0 Domain of unknown function (DUF4373) DUF21 PF01595.15 KFM03565.1 - 0.063 12.5 1.7 0.74 9.0 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF21 SRI PF08236.6 KFM03565.1 - 0.076 12.9 3.3 0.22 11.5 0.2 2.6 2 1 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain Toprim_2 PF13155.1 KFM03565.1 - 0.13 12.5 3.6 7.5 6.9 0.6 2.3 1 1 1 2 2 2 0 Toprim-like TBPIP PF07106.8 KFM03565.1 - 0.24 10.9 4.8 1.4 8.4 0.7 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) MgtE_N PF03448.12 KFM03565.1 - 0.59 10.4 4.1 0.39 11.0 0.5 2.2 3 0 0 3 3 2 0 MgtE intracellular N domain DUF892 PF05974.7 KFM03565.1 - 0.7 9.6 3.7 2.1 8.1 0.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF892) DJ-1_PfpI PF01965.19 KFM03566.1 - 1.2e-15 57.2 0.5 1.7e-15 56.7 0.4 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Sua5_yciO_yrdC PF01300.13 KFM03567.1 - 1.4e-34 118.9 0.0 2e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination MmgE_PrpD PF03972.9 KFM03568.1 - 6e-58 196.0 0.0 7.3e-58 195.8 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Glyoxalase PF00903.20 KFM03569.1 - 1.7e-08 34.5 0.0 1.7e-05 24.8 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KFM03569.1 - 3.7e-06 27.5 0.0 0.00082 19.9 0.0 2.1 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.1 KFM03569.1 - 0.029 14.2 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KFM03569.1 - 0.084 12.8 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Sec3_C PF09763.4 KFM03570.1 - 8.9e-76 255.5 10.8 1.3e-75 254.9 7.5 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 Blo-t-5 PF11642.3 KFM03570.1 - 0.62 9.8 4.6 2 8.2 0.0 3.0 3 1 1 4 4 4 0 Mite allergen Blo t 5 BTB_2 PF02214.17 KFM03571.1 - 9.6e-15 54.5 0.0 1.8e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain RMP PF14996.1 KFM03571.1 - 0.12 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Retinal Maintenance zf-C2H2 PF00096.21 KFM03572.1 - 3e-13 49.2 25.3 0.00018 21.6 0.4 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM03572.1 - 1.6e-09 37.5 25.1 9.7e-06 25.6 0.4 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM03572.1 - 2.9e-08 33.4 23.2 0.0072 16.5 0.8 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger DBD_Tnp_Mut PF03108.10 KFM03572.1 - 0.11 12.1 0.7 0.6 9.7 0.3 2.1 2 0 0 2 2 2 0 MuDR family transposase RPAP2_Rtr1 PF04181.8 KFM03572.1 - 1.3 9.1 4.5 3.9 7.6 3.1 1.8 1 1 0 1 1 1 0 Rtr1/RPAP2 family zf-C2H2_jaz PF12171.3 KFM03572.1 - 3.3 7.9 8.8 10 6.3 0.5 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Gtr1_RagA PF04670.7 KFM03573.1 - 6.1e-108 359.3 1.0 7.6e-108 359.0 0.7 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 KFM03573.1 - 2.7e-08 33.3 0.0 6e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Ras family Arf PF00025.16 KFM03573.1 - 2.2e-07 30.3 0.1 4.3e-07 29.3 0.0 1.5 1 1 1 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFM03573.1 - 8.6e-06 25.6 0.0 1.8e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KFM03573.1 - 0.00011 22.6 0.1 0.0004 20.8 0.0 2.0 2 1 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 KFM03573.1 - 0.0019 17.6 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KFM03573.1 - 0.021 14.0 0.0 0.036 13.2 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF815 PF05673.8 KFM03573.1 - 0.043 12.7 1.3 0.62 8.9 0.0 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF815) ABC_tran PF00005.22 KFM03573.1 - 0.15 12.3 0.1 0.25 11.6 0.1 1.7 1 1 0 1 1 1 0 ABC transporter DUF4606 PF15379.1 KFM03574.1 - 6.8e-32 109.6 0.4 7.4e-32 109.5 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4606) SICA_C PF12879.2 KFM03574.1 - 0.053 13.3 0.1 0.058 13.2 0.0 1.1 1 0 0 1 1 1 0 SICA C-terminal inner membrane domain Myotub-related PF06602.9 KFM03575.1 - 7.5e-144 478.8 0.0 9.5e-144 478.5 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.22 KFM03575.1 - 0.00012 21.5 0.0 0.00025 20.4 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 KFM03575.1 - 0.0012 18.2 0.1 0.098 12.0 0.1 2.5 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 KFM03575.1 - 0.0018 18.5 0.1 0.0049 17.1 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family Vps36_ESCRT-II PF11605.3 KFM03575.1 - 0.0018 18.0 0.0 0.0036 17.0 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 DSPc PF00782.15 KFM03575.1 - 0.0024 17.4 0.1 0.011 15.3 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Ank PF00023.25 KFM03576.1 - 2.1e-33 112.4 4.0 7.1e-07 28.7 0.0 5.7 6 0 0 6 6 6 5 Ankyrin repeat Ank_2 PF12796.2 KFM03576.1 - 3.6e-31 107.3 0.1 1.5e-14 54.0 0.0 2.7 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KFM03576.1 - 1.5e-22 77.4 0.5 0.00021 21.2 0.0 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 KFM03576.1 - 4.8e-20 71.5 0.2 1.4e-09 38.1 0.0 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM03576.1 - 6.5e-20 70.7 4.1 1.5e-05 25.0 0.0 5.6 3 2 3 6 6 6 4 Ankyrin repeats (many copies) SOCS_box PF07525.11 KFM03576.1 - 1.9e-05 24.3 0.0 1.9e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 SOCS box WTX PF09422.5 KFM03577.1 - 1e-61 209.3 23.6 2e-46 158.9 11.1 3.0 2 1 0 2 2 2 2 WTX protein RhoGEF PF00621.15 KFM03579.1 - 9.7e-47 159.1 2.4 9.7e-47 159.1 1.7 1.8 2 1 0 2 2 2 1 RhoGEF domain SH3_9 PF14604.1 KFM03579.1 - 1.4e-12 46.9 0.2 3e-12 45.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM03579.1 - 2.2e-10 39.7 1.8 4.8e-10 38.6 1.3 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFM03579.1 - 1.4e-09 37.2 0.1 3.4e-09 36.0 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 KFM03579.1 - 2.3e-06 27.7 0.2 4.8e-06 26.7 0.2 1.5 1 0 0 1 1 1 1 PH domain CSD PF00313.17 KFM03579.1 - 0.057 13.1 0.2 0.14 11.9 0.2 1.6 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain SH3_3 PF08239.6 KFM03579.1 - 0.086 13.0 0.3 0.18 11.9 0.2 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain Pkinase_Tyr PF07714.12 KFM03580.1 - 2.1e-102 341.6 0.0 3.3e-102 340.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM03580.1 - 1.5e-45 155.4 0.0 2e-31 109.1 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain I-set PF07679.11 KFM03580.1 - 4.1e-34 116.3 1.6 1.6e-19 69.5 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM03580.1 - 1.6e-22 79.3 3.9 2.6e-10 40.2 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin domain Ig_3 PF13927.1 KFM03580.1 - 2.8e-20 72.5 6.2 2e-09 37.8 0.0 3.7 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.20 KFM03580.1 - 4.3e-14 52.3 2.0 7.4e-06 25.9 0.0 3.8 4 1 0 4 4 4 2 Immunoglobulin domain V-set PF07686.12 KFM03580.1 - 5.8e-13 48.7 7.2 5.3e-07 29.5 0.8 4.6 3 2 0 3 3 3 2 Immunoglobulin V-set domain Herpes_gE PF02480.11 KFM03580.1 - 0.0013 17.1 0.1 0.64 8.2 0.0 2.6 1 1 1 2 2 2 2 Alphaherpesvirus glycoprotein E C2-set_2 PF08205.7 KFM03580.1 - 0.004 17.0 0.1 0.014 15.2 0.0 1.9 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain FAM176 PF14851.1 KFM03580.1 - 0.039 13.6 0.1 3.8 7.1 0.0 2.8 3 0 0 3 3 3 0 FAM176 family Caudal_act PF04731.7 KFM03581.1 - 1.4e-52 177.6 14.6 1.8e-52 177.3 10.1 1.1 1 0 0 1 1 1 1 Caudal like protein activation region Homeobox PF00046.24 KFM03581.1 - 2.5e-10 39.7 1.0 4e-10 39.1 0.7 1.3 1 0 0 1 1 1 1 Homeobox domain Caudal_act PF04731.7 KFM03582.1 - 3.6e-52 176.3 14.1 4.7e-52 175.9 9.8 1.1 1 0 0 1 1 1 1 Caudal like protein activation region Homeobox PF00046.24 KFM03582.1 - 6.6e-11 41.6 0.2 1e-10 41.0 0.1 1.3 1 0 0 1 1 1 1 Homeobox domain SRA1 PF07304.6 KFM03582.1 - 0.089 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) Erf4 PF10256.4 KFM03583.1 - 1.1e-25 89.8 0.1 1.2e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Fip1 PF05182.8 KFM03584.1 - 3.1e-26 90.3 0.7 6.7e-26 89.2 0.5 1.6 1 0 0 1 1 1 1 Fip1 motif PDZ PF00595.19 KFM03585.1 - 2.9e-63 210.0 4.3 2.1e-16 59.8 0.1 4.2 4 0 0 4 4 4 4 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM03585.1 - 1.2e-22 79.5 0.4 0.00065 19.5 0.0 4.4 4 0 0 4 4 4 4 PDZ domain zf-C3HC4 PF00097.20 KFM03585.1 - 2.2e-07 30.3 8.6 5.7e-07 29.0 5.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM03585.1 - 3.1e-06 27.1 7.2 1e-05 25.4 5.0 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM03585.1 - 4.5e-06 26.4 7.4 4.5e-06 26.4 5.1 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KFM03585.1 - 7.5e-06 25.5 6.5 2.4e-05 23.9 4.5 1.9 1 0 0 1 1 1 1 zinc-RING finger domain Tricorn_PDZ PF14685.1 KFM03585.1 - 1e-05 25.2 0.1 8.7 6.2 0.0 4.4 4 0 0 4 4 4 2 Tricorn protease PDZ domain zf-C3HC4_4 PF15227.1 KFM03585.1 - 1.5e-05 24.7 9.5 5e-05 23.0 6.6 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KFM03585.1 - 2.8e-05 23.7 6.4 7.2e-05 22.4 4.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 KFM03585.1 - 3.8e-05 23.2 3.6 3.8e-05 23.2 2.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.10 KFM03585.1 - 0.005 16.7 0.3 0.15 12.0 0.0 2.8 1 1 1 2 2 2 1 U-box domain zf-TRAF PF02176.13 KFM03585.1 - 0.0067 16.7 1.2 0.019 15.3 0.8 1.7 1 0 0 1 1 1 1 TRAF-type zinc finger SRP-alpha_N PF04086.8 KFM03585.1 - 0.19 11.0 1.6 0.23 10.8 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal zf-rbx1 PF12678.2 KFM03585.1 - 0.38 10.8 10.0 0.038 14.0 3.1 2.2 2 1 0 2 2 2 0 RING-H2 zinc finger Ras PF00071.17 KFM03586.1 - 3.5e-19 68.7 0.0 1.5e-18 66.7 0.0 1.8 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KFM03586.1 - 1.9e-08 34.8 0.0 4.4e-08 33.6 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFM03586.1 - 0.081 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family 7tm_1 PF00001.16 KFM03587.1 - 1.7e-41 142.1 13.9 2e-41 141.8 9.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM03587.1 - 3.8e-05 22.9 5.3 5.9e-05 22.3 3.7 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx CAAD PF14159.1 KFM03587.1 - 0.19 11.4 1.5 0.71 9.5 0.0 2.6 3 0 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase MFS_1 PF07690.11 KFM03588.1 - 1.3e-25 89.8 42.5 3.8e-17 62.0 14.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Alba PF01918.16 KFM03588.1 - 0.043 13.4 0.0 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 Alba zf-RING_2 PF13639.1 KFM03589.1 - 5e-15 55.0 7.5 8.1e-15 54.3 5.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KFM03589.1 - 1.5e-09 37.8 2.6 2.8e-09 36.9 1.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KFM03589.1 - 1.6e-06 27.6 7.6 2.6e-06 26.9 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM03589.1 - 8.8e-06 25.2 4.2 1.3e-05 24.7 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM03589.1 - 1.3e-05 24.7 6.4 2.1e-05 24.1 4.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KFM03589.1 - 3.8e-05 23.4 1.4 7.9e-05 22.4 1.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 KFM03589.1 - 6.7e-05 22.8 7.5 0.00011 22.1 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KFM03589.1 - 0.048 13.2 4.4 0.085 12.4 3.0 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 KFM03589.1 - 0.054 13.0 2.2 0.1 12.1 1.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING-like PF08746.6 KFM03589.1 - 1.1 9.3 7.0 1.9 8.5 4.8 1.4 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.2 KFM03589.1 - 1.2 9.2 7.5 2.2 8.3 5.2 1.5 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 KFM03589.1 - 1.7 8.6 5.2 6.1 6.8 3.6 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain UPRTase PF14681.1 KFM03590.1 - 5.9e-30 104.0 0.0 7.1e-30 103.7 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KFM03590.1 - 1.9e-05 24.4 0.0 2.5e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain 14-3-3 PF00244.15 KFM03590.1 - 0.088 11.8 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 14-3-3 protein DUF3049 PF11250.3 KFM03592.1 - 0.26 11.0 1.2 1.7 8.4 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3049) ABC_tran PF00005.22 KFM03593.1 - 5.6e-34 117.3 0.0 1.3e-33 116.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KFM03593.1 - 1.2e-28 100.3 10.2 1.5e-28 99.9 7.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_16 PF13191.1 KFM03593.1 - 7.3e-06 26.0 0.0 0.00081 19.4 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.14 KFM03593.1 - 4.9e-05 22.6 1.0 0.01 15.0 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KFM03593.1 - 0.0002 20.8 0.2 0.00064 19.1 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 KFM03593.1 - 0.00091 20.0 0.1 0.0035 18.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KFM03593.1 - 0.0027 17.7 0.3 0.097 12.6 0.1 2.7 2 1 1 3 3 3 1 AAA domain DUF87 PF01935.12 KFM03593.1 - 0.0079 16.0 0.7 0.019 14.8 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF87 ATP-synt_ab PF00006.20 KFM03593.1 - 0.022 14.2 0.2 0.051 13.0 0.1 1.7 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.1 KFM03593.1 - 0.024 14.9 0.5 0.13 12.6 0.0 2.4 3 0 0 3 3 2 0 AAA domain AAA_10 PF12846.2 KFM03593.1 - 0.028 13.8 0.1 0.14 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain AAA_22 PF13401.1 KFM03593.1 - 0.028 14.5 0.2 0.2 11.7 0.1 2.3 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KFM03593.1 - 0.032 13.7 0.1 0.061 12.7 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_14 PF13173.1 KFM03593.1 - 0.038 13.8 0.4 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 KFM03593.1 - 0.04 13.1 0.1 0.14 11.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_19 PF13245.1 KFM03593.1 - 0.044 13.5 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_21 PF13304.1 KFM03593.1 - 0.045 13.7 1.7 0.19 11.6 0.1 2.7 2 1 0 2 2 2 0 AAA domain Miro PF08477.8 KFM03593.1 - 0.063 13.7 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA_30 PF13604.1 KFM03593.1 - 0.14 11.7 0.0 0.36 10.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain UPRTase PF14681.1 KFM03594.1 - 3.1e-49 167.0 0.0 3.6e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KFM03594.1 - 3.2e-05 23.6 0.0 4.3e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain 14-3-3 PF00244.15 KFM03594.1 - 0.085 11.9 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 14-3-3 protein Ependymin PF00811.13 KFM03595.1 - 8.8e-40 135.4 0.2 9.8e-40 135.3 0.2 1.0 1 0 0 1 1 1 1 Ependymin Fz PF01392.17 KFM03596.1 - 1.3e-31 109.3 1.0 2.9e-31 108.2 0.7 1.6 1 0 0 1 1 1 1 Fz domain NTR PF01759.16 KFM03596.1 - 1.5e-16 59.9 0.4 1.5e-16 59.9 0.3 2.1 1 1 1 2 2 2 1 UNC-6/NTR/C345C module Thioredoxin PF00085.15 KFM03597.1 - 1.9e-05 24.3 0.1 2.8e-05 23.7 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 KFM03597.1 - 0.00098 18.8 0.0 0.001 18.7 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KFM03597.1 - 0.003 17.1 0.1 0.003 17.1 0.0 1.0 1 0 0 1 1 1 1 Redoxin Glutaredoxin PF00462.19 KFM03597.1 - 0.011 15.7 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin Thioredoxin_8 PF13905.1 KFM03597.1 - 0.024 14.7 0.0 0.026 14.6 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin-like 7tm_1 PF00001.16 KFM03598.1 - 1e-11 44.4 28.9 1.4e-11 43.9 20.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF998 PF06197.8 KFM03598.1 - 0.57 9.4 12.8 0.35 10.1 7.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF998) DUF3493 PF11998.3 KFM03598.1 - 5 7.0 9.1 2.7 7.9 1.7 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3493) DUF3361 PF11841.3 KFM03599.1 - 2.1e-72 242.0 2.7 5.1e-72 240.8 1.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) ELMO_CED12 PF04727.8 KFM03599.1 - 3.5e-49 166.6 0.6 6.7e-49 165.6 0.4 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family FERM_N PF09379.5 KFM03599.1 - 0.028 14.4 0.0 0.18 11.8 0.0 2.4 2 0 0 2 2 2 0 FERM N-terminal domain Lipase_GDSL PF00657.17 KFM03600.1 - 5.1e-14 52.6 0.0 7.7e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KFM03600.1 - 4.7e-05 23.5 0.0 0.00011 22.4 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Cu-binding_MopE PF11617.3 KFM03600.1 - 0.035 13.8 1.7 0.12 12.1 1.2 1.9 1 1 0 1 1 1 0 Protein metal binding site Anillin PF08174.6 KFM03601.1 - 5.7e-22 78.2 0.1 3e-21 75.9 0.1 2.4 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 KFM03601.1 - 1.3e-15 57.4 0.3 1.1e-14 54.4 0.1 2.7 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 KFM03601.1 - 0.00054 20.1 1.0 0.0013 18.9 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain zf-C2H2_6 PF13912.1 KFM03601.1 - 0.067 13.1 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger DUF1704 PF08014.6 KFM03602.1 - 4e-14 52.3 0.0 5.3e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1704) HHH_3 PF12836.2 KFM03603.1 - 1.9e-41 139.8 0.1 1.5e-20 72.9 0.1 2.4 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH PF00633.18 KFM03603.1 - 2.7e-17 61.4 0.1 2.4e-06 26.9 0.0 3.9 4 0 0 4 4 4 3 Helix-hairpin-helix motif HHH_5 PF14520.1 KFM03603.1 - 4.8e-09 36.2 0.0 1.8e-06 28.0 0.0 3.6 2 1 1 3 3 3 2 Helix-hairpin-helix domain HHH_2 PF12826.2 KFM03603.1 - 6.4e-09 35.5 0.1 0.005 16.7 0.0 2.9 3 0 0 3 3 3 2 Helix-hairpin-helix motif Exo_endo_phos PF03372.18 KFM03603.1 - 1.4e-08 35.0 0.1 2.3e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HHH_6 PF14579.1 KFM03603.1 - 3.5e-08 33.3 0.0 0.00022 21.2 0.0 2.5 2 0 0 2 2 2 2 Helix-hairpin-helix motif T2SK PF03934.8 KFM03603.1 - 3.6e-08 32.9 0.0 0.0019 17.4 0.0 2.2 2 0 0 2 2 2 2 Type II secretion system (T2SS), protein K Exo_endo_phos_2 PF14529.1 KFM03603.1 - 0.0018 17.8 0.5 0.0058 16.2 0.3 2.0 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase PsbU PF06514.6 KFM03603.1 - 0.0057 16.4 0.0 0.48 10.2 0.0 2.4 2 0 0 2 2 2 1 Photosystem II 12 kDa extrinsic protein (PsbU) Septin PF00735.13 KFM03604.1 - 3.5e-123 410.0 0.1 4e-123 409.9 0.1 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KFM03604.1 - 8.4e-08 32.1 0.0 2.6e-07 30.6 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KFM03604.1 - 3.6e-05 23.0 1.3 7e-05 22.0 0.2 2.0 2 1 0 2 2 2 1 Protein of unknown function, DUF258 AIG1 PF04548.11 KFM03604.1 - 0.00015 20.9 0.1 0.00044 19.4 0.0 1.8 2 0 0 2 2 2 1 AIG1 family Gtr1_RagA PF04670.7 KFM03604.1 - 0.00027 20.1 1.3 0.02 14.0 0.0 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Dynamin_N PF00350.18 KFM03604.1 - 0.001 18.9 3.3 0.13 12.0 0.1 2.9 2 1 1 3 3 3 2 Dynamin family AAA_22 PF13401.1 KFM03604.1 - 0.0026 17.8 0.0 0.0083 16.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KFM03604.1 - 0.0034 17.8 0.4 0.015 15.7 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein ABC_tran PF00005.22 KFM03604.1 - 0.0043 17.3 0.0 0.011 15.9 0.0 1.8 2 0 0 2 2 2 1 ABC transporter Ras PF00071.17 KFM03604.1 - 0.006 15.9 0.1 0.017 14.5 0.0 1.8 2 0 0 2 2 2 1 Ras family AAA_10 PF12846.2 KFM03604.1 - 0.0083 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain FeoB_N PF02421.13 KFM03604.1 - 0.015 14.5 0.0 0.032 13.4 0.0 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.1 KFM03604.1 - 0.018 15.0 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 KFM03604.1 - 0.024 14.1 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 KFM03604.1 - 0.04 13.6 0.0 0.1 12.2 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 KFM03604.1 - 0.07 12.9 0.1 9.5 5.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 NTPase_1 PF03266.10 KFM03604.1 - 0.093 12.4 0.4 8.8 6.0 0.0 2.3 2 0 0 2 2 2 0 NTPase FtsK_SpoIIIE PF01580.13 KFM03604.1 - 0.1 12.0 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family cobW PF02492.14 KFM03604.1 - 0.62 9.4 3.0 15 4.9 0.0 2.7 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain DUF1542 PF07564.6 KFM03604.1 - 0.88 9.6 3.8 3.9 7.5 2.7 1.9 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1542) ubiquitin PF00240.18 KFM03605.1 - 5.1e-07 28.9 0.1 7.5e-07 28.4 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 KFM03605.1 - 6.2e-05 23.1 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 KFM03605.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Golgin_A5 PF09787.4 KFM03605.1 - 1 7.8 3.0 1.5 7.2 2.1 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 T-box PF00907.17 KFM03606.1 - 7.2e-61 204.8 0.2 7.9e-61 204.7 0.1 1.0 1 0 0 1 1 1 1 T-box Dpy19 PF10034.4 KFM03607.1 - 6.6e-247 820.8 20.0 8.9e-247 820.3 13.8 1.2 1 0 0 1 1 1 1 Q-cell neuroblast polarisation 7tm_1 PF00001.16 KFM03608.1 - 1.5e-46 158.6 14.9 2.1e-46 158.1 10.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 KFM03608.1 - 7.2 6.3 12.6 0.91 9.3 4.3 2.7 2 1 0 3 3 3 0 Olfactory receptor VWD PF00094.20 KFM03609.1 - 2.3e-37 128.6 0.2 5.4e-37 127.4 0.1 1.7 1 0 0 1 1 1 1 von Willebrand factor type D domain VWC PF00093.13 KFM03609.1 - 3.6e-24 84.6 146.9 5.5e-10 39.2 9.9 8.0 6 1 0 6 6 6 5 von Willebrand factor type C domain C8 PF08742.6 KFM03609.1 - 1.7e-18 66.6 14.2 1.7e-18 66.6 9.8 4.2 3 1 1 4 4 4 1 C8 domain TIL PF01826.12 KFM03609.1 - 1.7e-10 40.8 14.5 1.7e-10 40.8 10.1 9.1 4 2 3 7 7 7 1 Trypsin Inhibitor like cysteine rich domain PHTB1_N PF14727.1 KFM03610.1 - 7.8e-172 571.9 0.0 9.9e-172 571.5 0.0 1.1 1 0 0 1 1 1 1 PTHB1 N-terminus PHTB1_C PF14728.1 KFM03610.1 - 8.4e-149 495.4 2.7 8.4e-149 495.4 1.8 1.5 2 0 0 2 2 2 1 PTHB1 C-terminus dTMP_synthase PF02593.9 KFM03610.1 - 0.14 11.4 0.9 0.27 10.5 0.6 1.3 1 0 0 1 1 1 0 Thymidylate synthase UMPH-1 PF05822.7 KFM03611.1 - 1.2e-119 398.1 5.4 1.4e-119 397.9 3.8 1.0 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.2 KFM03611.1 - 5e-05 23.5 0.2 8.2e-05 22.8 0.1 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase ACT_7 PF13840.1 KFM03611.1 - 0.0015 18.0 0.3 3.9 7.0 0.0 3.2 3 0 0 3 3 3 2 ACT domain NIF PF03031.13 KFM03611.1 - 0.006 16.2 0.3 0.77 9.4 0.0 2.6 1 1 0 2 2 2 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 KFM03611.1 - 0.022 14.9 0.0 0.07 13.3 0.0 1.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase FKBP_C PF00254.23 KFM03612.1 - 2.9e-105 344.5 0.0 1.3e-26 92.3 0.0 5.1 5 0 0 5 5 5 4 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_1 PF00036.27 KFM03612.1 - 9.7e-10 37.0 0.8 0.00034 19.6 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 KFM03612.1 - 1.5e-07 31.4 4.1 1.2e-05 25.3 0.6 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KFM03612.1 - 3.3e-05 23.3 0.4 0.26 11.2 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 KFM03612.1 - 7.5e-05 22.2 0.2 0.28 10.8 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KFM03612.1 - 9.6e-05 21.5 0.3 0.18 11.2 0.0 2.6 2 0 0 2 2 2 2 EF hand zf-CCHC_6 PF15288.1 KFM03613.1 - 0.0077 15.8 0.9 0.019 14.6 0.6 1.7 1 0 0 1 1 1 1 Zinc knuckle RXT2_N PF08595.6 KFM03613.1 - 0.024 14.4 5.7 0.035 13.8 4.0 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF3245 PF11595.3 KFM03613.1 - 0.33 11.1 9.2 0.51 10.5 6.3 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) CDC45 PF02724.9 KFM03613.1 - 0.56 8.1 9.1 0.6 8.0 6.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.6 KFM03613.1 - 8.2 4.1 9.5 9.3 3.9 6.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PBP1_TM PF14812.1 KFM03613.1 - 9.5 6.6 13.8 15 5.9 9.6 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Kelch_6 PF13964.1 KFM03615.1 - 1.8e-21 75.3 7.5 6.5e-07 29.2 0.0 5.4 4 2 1 5 5 5 3 Kelch motif BACK PF07707.10 KFM03615.1 - 2.4e-20 72.2 1.4 4.2e-20 71.4 0.9 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_1 PF01344.20 KFM03615.1 - 5.3e-19 67.5 20.0 7.8e-09 34.9 0.0 7.5 6 2 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 KFM03615.1 - 4.5e-09 35.7 5.0 0.031 14.0 0.0 5.1 4 1 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 KFM03615.1 - 1.3e-07 31.6 0.3 0.015 15.4 0.0 4.0 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_4 PF13418.1 KFM03615.1 - 6.4e-05 22.6 8.5 0.31 10.8 0.0 5.3 3 2 1 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 KFM03615.1 - 0.00054 19.8 0.3 4 7.4 0.1 3.8 3 0 0 3 3 3 1 Kelch motif Avl9 PF09794.4 KFM03616.1 - 3.2e-147 489.9 0.0 4e-147 489.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.4 KFM03616.1 - 6.1e-10 38.8 0.8 8.6e-07 28.5 0.5 3.2 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.5 KFM03616.1 - 9.1e-08 31.7 0.0 0.00015 21.4 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis DENN PF02141.16 KFM03616.1 - 0.0023 17.6 1.1 1.1 8.9 0.0 2.5 2 0 0 2 2 2 2 DENN (AEX-3) domain LSM PF01423.17 KFM03617.1 - 2.6e-19 68.5 0.5 2.8e-19 68.4 0.4 1.0 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.2 KFM03617.1 - 0.07 12.9 0.0 0.092 12.5 0.0 1.3 1 1 0 1 1 1 0 Scd6-like Sm domain DCX PF03607.12 KFM03617.1 - 0.1 12.1 0.1 0.41 10.2 0.0 1.8 2 0 0 2 2 2 0 Doublecortin PDEase_I PF00233.14 KFM03619.1 - 3e-96 321.7 4.9 5.3e-96 320.9 3.4 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I_N PF08499.7 KFM03619.1 - 2.7e-28 97.6 2.9 2.8e-28 97.5 0.0 2.3 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase N-terminal TEX19 PF15553.1 KFM03619.1 - 0.38 10.6 4.6 0.81 9.5 3.2 1.5 1 0 0 1 1 1 0 Testis-expressed protein 19 Gag_p30 PF02093.11 KFM03620.1 - 9.2e-21 74.0 0.1 1.1e-20 73.8 0.1 1.0 1 0 0 1 1 1 1 Gag P30 core shell protein Gag_p24 PF00607.15 KFM03620.1 - 7e-05 22.4 0.3 0.00016 21.2 0.2 1.6 1 1 0 1 1 1 1 gag gene protein p24 (core nucleocapsid protein) GED PF02212.13 KFM03620.1 - 0.11 12.3 0.1 1.1 9.2 0.0 2.1 2 0 0 2 2 2 0 Dynamin GTPase effector domain DUF4463 PF14703.1 KFM03621.1 - 2.5 8.6 6.7 0.64 10.5 1.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) Neuro_bHLH PF12533.3 KFM03622.1 - 2.7e-43 147.5 2.3 2.7e-43 147.5 1.6 2.2 2 0 0 2 2 2 1 Neuronal helix-loop-helix transcription factor HLH PF00010.21 KFM03622.1 - 2.5e-16 59.0 0.8 2.5e-16 59.0 0.6 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Myc_N PF01056.13 KFM03622.1 - 1.4 7.9 9.7 0.12 11.5 2.4 1.9 2 0 0 2 2 2 0 Myc amino-terminal region Integrin_alpha2 PF08441.7 KFM03623.1 - 7.7e-96 321.7 0.1 1e-95 321.2 0.0 1.1 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.18 KFM03623.1 - 3.9e-17 61.4 16.5 8.6e-06 25.2 0.1 4.5 4 0 0 4 4 4 3 FG-GAP repeat VCBS PF13517.1 KFM03623.1 - 9.6e-10 38.6 10.8 6.1e-08 32.9 1.8 3.0 1 1 1 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha PF00357.15 KFM03623.1 - 0.0011 18.6 0.2 0.0034 17.0 0.2 2.0 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region FG-GAP_2 PF14312.1 KFM03623.1 - 0.0054 16.7 1.0 0.0054 16.7 0.7 4.6 5 0 0 5 5 5 2 FG-GAP repeat C1-set PF07654.10 KFM03624.1 - 1.6e-13 50.4 2.0 4.4e-13 49.0 0.2 2.0 2 0 0 2 2 2 1 Immunoglobulin C1-set domain V-set PF07686.12 KFM03624.1 - 2.9e-13 49.7 0.4 6.8e-13 48.5 0.1 1.7 2 0 0 2 2 2 1 Immunoglobulin V-set domain ig PF00047.20 KFM03624.1 - 0.09 12.9 0.3 0.42 10.7 0.2 2.3 1 1 0 1 1 1 0 Immunoglobulin domain BAR PF03114.13 KFM03626.1 - 6.1e-53 179.6 6.7 1.1e-52 178.8 4.6 1.4 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 KFM03626.1 - 1.8e-09 37.0 0.0 3.8e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM03626.1 - 2.4e-06 26.8 0.1 2.2e-05 23.7 0.0 2.3 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFM03626.1 - 9e-05 21.8 0.0 0.00019 20.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Arfaptin PF06456.8 KFM03626.1 - 0.0063 15.8 3.4 0.0095 15.3 2.4 1.3 1 0 0 1 1 1 1 Arfaptin-like domain HD_3 PF13023.1 KFM03626.1 - 0.086 12.5 0.3 0.086 12.5 0.2 2.5 2 0 0 2 2 2 0 HD domain EzrA PF06160.7 KFM03626.1 - 0.15 10.1 4.6 1.2 7.1 0.3 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Occludin_ELL PF07303.8 KFM03626.1 - 1.6 9.5 6.0 17 6.2 0.4 2.6 2 0 0 2 2 2 0 Occludin homology domain GAS PF13851.1 KFM03626.1 - 3.8 6.6 7.5 9.9 5.2 0.7 2.8 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Clathrin PF00637.15 KFM03627.1 - 4.2e-26 91.2 1.2 4.2e-26 91.2 0.8 2.6 3 0 0 3 3 3 1 Region in Clathrin and VPS Vps39_1 PF10366.4 KFM03627.1 - 0.00032 20.6 5.6 0.0012 18.7 0.1 3.4 3 1 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 KFM03627.1 - 0.0011 19.1 0.7 0.003 17.7 0.5 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.1 KFM03627.1 - 0.0046 16.7 5.5 0.016 15.0 3.8 2.0 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KFM03627.1 - 0.029 14.4 2.7 0.093 12.8 1.9 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger TPR_19 PF14559.1 KFM03627.1 - 0.92 9.8 4.1 2.9 8.3 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C3HC4_3 PF13920.1 KFM03627.1 - 1.6 8.4 9.2 0.31 10.7 3.3 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM03627.1 - 2.7 7.8 11.4 0.28 10.9 4.2 2.3 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFM03627.1 - 6.4 6.9 13.0 7.9 6.5 6.1 3.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pou PF00157.12 KFM03628.1 - 1e-24 85.9 3.0 1.5e-16 59.7 0.0 3.2 4 0 0 4 4 4 2 Pou domain - N-terminal to homeobox domain Homeobox PF00046.24 KFM03628.1 - 2.2e-18 65.5 0.9 8.8e-18 63.6 0.6 2.1 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFM03628.1 - 0.014 15.1 0.0 0.7 9.6 0.0 2.6 2 0 0 2 2 2 0 Homeobox KN domain DUF4175 PF13779.1 KFM03628.1 - 0.33 8.6 33.5 0.55 7.8 23.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) ArfGap PF01412.13 KFM03629.1 - 4.6e-36 123.1 0.0 1.3e-35 121.6 0.0 1.9 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ank_2 PF12796.2 KFM03629.1 - 5.8e-12 45.7 0.1 4e-11 43.0 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) SH3_9 PF14604.1 KFM03629.1 - 2.5e-10 39.7 0.1 4.7e-10 38.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM03629.1 - 9.9e-10 37.6 0.3 2e-09 36.6 0.2 1.6 1 0 0 1 1 1 1 SH3 domain Ank PF00023.25 KFM03629.1 - 1e-09 37.6 0.4 0.0028 17.3 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat PH PF00169.24 KFM03629.1 - 1.5e-09 38.0 0.5 3.6e-09 36.7 0.4 1.7 1 0 0 1 1 1 1 PH domain Ank_5 PF13857.1 KFM03629.1 - 4.9e-07 29.7 0.3 2e-05 24.6 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) SH3_2 PF07653.12 KFM03629.1 - 1e-06 28.1 0.2 2.2e-06 27.0 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain Ank_3 PF13606.1 KFM03629.1 - 4.2e-06 26.4 0.5 0.21 11.9 0.0 3.6 4 0 0 4 4 2 2 Ankyrin repeat Ank_4 PF13637.1 KFM03629.1 - 5.6e-06 26.7 0.1 0.0018 18.6 0.0 2.9 1 1 0 2 2 2 1 Ankyrin repeats (many copies) PH_3 PF14593.1 KFM03629.1 - 0.018 14.8 0.1 0.073 12.9 0.1 2.0 2 0 0 2 2 2 0 PH domain PH_9 PF15410.1 KFM03629.1 - 0.13 12.4 2.0 2.9 8.0 0.3 2.8 2 1 0 2 2 2 0 Pleckstrin homology domain DUF4404 PF14357.1 KFM03629.1 - 0.66 10.4 8.8 0.17 12.3 2.5 2.7 3 0 0 3 3 2 0 Domain of unknown function (DUF4404) A2L_zn_ribbon PF08792.5 KFM03629.1 - 1.6 8.3 5.0 9.9 5.7 3.4 2.2 1 1 0 1 1 1 0 A2L zinc ribbon domain DUF1394 PF07159.7 KFM03630.1 - 2.9e-166 552.0 0.0 3.4e-166 551.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) WASH-7_N PF14745.1 KFM03630.1 - 0.0063 14.7 0.1 0.025 12.7 0.0 1.8 1 1 1 2 2 2 1 WASH complex subunit 7, N-terminal V-ATPase_H_N PF03224.9 KFM03630.1 - 0.01 15.0 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 V-ATPase subunit H NUDIX_4 PF14815.1 KFM03630.1 - 0.064 12.6 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 NUDIX domain Cul7 PF11515.3 KFM03631.1 - 3.7e-22 78.0 0.2 6.2e-22 77.2 0.1 1.4 1 0 0 1 1 1 1 Mouse development and cellular proliferation protein Cullin-7 Chromo PF00385.19 KFM03631.1 - 0.072 12.7 0.0 0.21 11.2 0.0 1.9 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain MOR2-PAG1_N PF14222.1 KFM03631.1 - 0.15 10.7 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 Cell morphogenesis N-terminal SRF-TF PF00319.13 KFM03632.1 - 2.2e-08 33.2 0.1 3.8e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) I-set PF07679.11 KFM03633.1 - 1.9e-86 284.0 0.0 2.7e-14 52.8 0.0 7.3 7 0 0 7 7 7 7 Immunoglobulin I-set domain Pkinase_Tyr PF07714.12 KFM03633.1 - 6.8e-83 277.7 0.0 9.5e-83 277.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ig_2 PF13895.1 KFM03633.1 - 4e-69 228.7 11.2 2.3e-12 46.8 0.1 7.2 7 0 0 7 7 7 7 Immunoglobulin domain Ig_3 PF13927.1 KFM03633.1 - 5.9e-50 167.6 8.9 1e-09 38.7 0.3 7.5 7 0 0 7 7 7 6 Immunoglobulin domain ig PF00047.20 KFM03633.1 - 1.2e-45 153.4 12.3 4.7e-09 36.2 0.2 7.9 7 2 0 7 7 7 6 Immunoglobulin domain Pkinase PF00069.20 KFM03633.1 - 1.4e-42 145.6 0.0 2.2e-42 145.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain V-set PF07686.12 KFM03633.1 - 3.1e-31 107.6 5.3 0.0001 22.1 0.1 8.5 7 3 0 7 7 7 6 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM03633.1 - 3.4e-14 52.5 11.6 0.011 15.6 0.1 7.0 7 0 0 7 7 7 4 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.11 KFM03633.1 - 4.7e-11 41.6 0.9 0.045 12.0 0.1 6.0 2 2 3 6 6 6 3 Alphaherpesvirus glycoprotein E C1-set PF07654.10 KFM03633.1 - 2.2e-08 33.9 1.5 0.61 10.1 0.0 6.0 5 0 0 5 5 5 2 Immunoglobulin C1-set domain C2-set PF05790.10 KFM03633.1 - 4.3e-06 26.6 0.2 1.2 9.1 0.0 5.9 6 0 0 6 6 6 1 Immunoglobulin C2-set domain V-set_CD47 PF08204.6 KFM03633.1 - 3.3e-05 23.6 0.2 0.36 10.5 0.0 4.1 4 0 0 4 4 4 2 CD47 immunoglobulin-like domain Sp38 PF07354.7 KFM03633.1 - 0.00025 19.7 0.8 0.34 9.5 0.0 4.3 4 1 1 5 5 5 1 Zona-pellucida-binding protein (Sp38) CD34_antigen PF06365.7 KFM03633.1 - 0.0069 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 CD34/Podocalyxin family SKG6 PF08693.5 KFM03633.1 - 0.043 13.1 0.3 0.094 12.0 0.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Rab5-bind PF09311.6 KFM03634.1 - 2.3e-66 223.1 23.3 1.7e-64 217.0 7.4 3.3 4 0 0 4 4 3 2 Rabaptin-like protein TPR_12 PF13424.1 KFM03634.1 - 3.6e-63 209.4 19.0 1.9e-22 78.9 0.6 5.7 4 1 3 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.1 KFM03634.1 - 9.6e-62 203.3 11.8 4.6e-16 58.1 0.0 6.6 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.23 KFM03634.1 - 7.4e-27 91.8 29.1 1.1e-07 31.1 0.3 6.8 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.1 KFM03634.1 - 2.8e-24 82.9 17.2 6.3e-06 25.5 0.0 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.1 KFM03634.1 - 5.4e-24 83.6 18.4 3.8e-10 39.2 1.6 4.8 4 1 1 5 5 5 4 TPR repeat TPR_16 PF13432.1 KFM03634.1 - 3.4e-20 72.1 3.8 7e-06 26.5 0.0 4.7 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFM03634.1 - 1.6e-18 65.0 25.3 0.00065 19.4 0.3 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.1 KFM03634.1 - 4.6e-14 52.5 9.3 0.00016 21.9 0.0 4.8 4 1 0 5 5 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFM03634.1 - 1.1e-12 47.3 6.1 0.49 11.1 0.0 6.8 3 1 4 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFM03634.1 - 1.8e-12 46.3 6.3 0.11 12.7 0.0 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFM03634.1 - 4.9e-12 44.7 20.1 0.069 12.9 0.3 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat Apc3 PF12895.2 KFM03634.1 - 6e-11 42.3 9.2 2.7e-05 24.2 0.1 3.4 2 1 1 3 3 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 KFM03634.1 - 7.8e-07 28.9 1.9 1.6 9.3 0.1 6.6 8 0 0 8 8 6 1 Tetratricopeptide repeat PPR PF01535.15 KFM03634.1 - 6.3e-05 22.6 1.6 0.084 12.8 0.0 4.5 6 0 0 6 6 4 1 PPR repeat SHNi-TPR PF10516.4 KFM03634.1 - 0.0015 17.7 1.8 3.5 6.9 0.0 4.3 4 0 0 4 4 4 1 SHNi-TPR DUF627 PF04781.7 KFM03634.1 - 0.019 14.5 1.1 7.9 6.1 0.0 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF627) DUF3972 PF13118.1 KFM03634.1 - 0.043 13.9 11.7 1.3 9.1 2.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3972) PPR_3 PF13812.1 KFM03634.1 - 0.065 13.5 0.5 19 5.8 0.0 4.2 5 0 0 5 5 3 0 Pentatricopeptide repeat domain PPR_2 PF13041.1 KFM03634.1 - 0.15 12.0 0.3 3.1 7.8 0.0 3.2 3 0 0 3 3 3 0 PPR repeat family Exonuc_VII_L PF02601.10 KFM03634.1 - 0.32 10.1 7.3 0.46 9.6 5.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit TPR_6 PF13174.1 KFM03634.1 - 0.54 10.8 15.1 1.3 9.5 0.1 6.1 7 0 0 7 7 5 0 Tetratricopeptide repeat TMF_DNA_bd PF12329.3 KFM03634.1 - 1.6 8.5 19.8 0.022 14.5 6.4 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF342 PF03961.8 KFM03634.1 - 1.8 6.8 7.7 3 6.1 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) COG2 PF06148.6 KFM03634.1 - 2.4 8.0 10.3 0.16 11.8 3.3 1.8 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Ribosomal_L2_C PF03947.13 KFM03635.1 - 4.9e-31 107.2 0.1 7.1e-31 106.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KFM03635.1 - 8.5e-08 32.0 0.3 2.5e-07 30.5 0.0 2.0 3 0 0 3 3 3 1 Ribosomal Proteins L2, RNA binding domain Cul7 PF11515.3 KFM03636.1 - 2.4e-29 101.0 0.2 4.2e-29 100.2 0.1 1.4 1 0 0 1 1 1 1 Mouse development and cellular proliferation protein Cullin-7 RCC1 PF00415.13 KFM03637.1 - 2.2e-48 162.2 13.4 2.2e-15 56.5 0.1 4.2 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KFM03637.1 - 1.6e-19 69.0 15.6 3.7e-08 32.7 1.0 4.5 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat X PF00739.14 KFM03637.1 - 0.0048 16.8 0.1 0.23 11.3 0.0 2.2 2 0 0 2 2 2 1 Trans-activation protein X HECT PF00632.20 KFM03638.1 - 6.6e-34 117.4 0.0 7.2e-34 117.3 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1 PF00415.13 KFM03639.1 - 1.9e-84 277.7 27.3 1.1e-14 54.3 0.1 7.7 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat HECT PF00632.20 KFM03639.1 - 1.5e-83 280.5 0.3 2.3e-83 279.9 0.2 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1_2 PF13540.1 KFM03639.1 - 2.2e-46 154.5 43.2 2.5e-09 36.4 0.0 7.7 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RhoGAP PF00620.22 KFM03640.1 - 4.4e-45 153.0 0.5 2.4e-44 150.6 0.0 2.3 2 0 0 2 2 2 1 RhoGAP domain Synuclein PF01387.12 KFM03642.1 - 1.4e-60 202.8 18.8 1.6e-60 202.7 13.0 1.0 1 0 0 1 1 1 1 Synuclein Orbi_VP5 PF00901.12 KFM03642.1 - 4.6 5.3 6.5 5 5.2 4.5 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 C1q PF00386.16 KFM03644.1 - 5.6e-24 84.5 0.0 3.3e-23 82.0 0.0 2.4 2 0 0 2 2 2 1 C1q domain EMI PF07546.8 KFM03644.1 - 5.3e-14 52.4 3.2 5.3e-14 52.4 2.2 2.2 2 0 0 2 2 2 1 EMI domain EGF PF00008.22 KFM03644.1 - 1.7e-05 24.6 6.7 1.7e-05 24.6 4.6 1.8 2 0 0 2 2 2 1 EGF-like domain YvrJ PF12841.2 KFM03644.1 - 0.25 10.6 2.9 3.6 6.9 0.4 3.8 2 0 0 2 2 2 0 YvrJ protein family CR6_interact PF10147.4 KFM03644.1 - 9 5.5 16.5 3.9 6.7 0.2 4.3 4 0 0 4 4 4 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 TMF_DNA_bd PF12329.3 KFM03646.1 - 0.019 14.7 0.7 0.028 14.2 0.1 1.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SNF2_N PF00176.18 KFM03649.1 - 8.7e-70 234.8 1.2 1.3e-69 234.2 0.9 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFM03649.1 - 9.8e-14 50.9 0.0 2.9e-13 49.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFM03649.1 - 2.2e-07 30.9 0.1 6.6e-06 26.0 0.0 3.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit CUE PF02845.11 KFM03649.1 - 4.6e-07 29.1 0.6 0.012 15.0 0.0 2.5 2 0 0 2 2 2 2 CUE domain DEAD PF00270.24 KFM03649.1 - 1.5e-06 27.8 0.0 8.5e-06 25.3 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase HHH_3 PF12836.2 KFM03649.1 - 0.024 14.5 0.0 0.065 13.1 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif MFMR PF07777.6 KFM03649.1 - 1.1 9.1 9.0 2.8 7.8 6.2 1.6 1 0 0 1 1 1 0 G-box binding protein MFMR GST_N PF02798.15 KFM03650.1 - 1.4e-20 73.2 0.0 2.8e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFM03650.1 - 1.1e-07 31.7 0.1 1.7e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KFM03650.1 - 1e-05 25.6 0.0 2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KFM03650.1 - 5.7e-05 23.5 0.3 0.00013 22.3 0.2 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFM03650.1 - 0.0034 17.2 0.8 0.021 14.7 0.5 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KFM03650.1 - 0.0071 16.3 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain 7tm_1 PF00001.16 KFM03651.1 - 4.7e-61 206.1 17.7 5.8e-61 205.8 12.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM03651.1 - 3.1e-16 59.3 13.6 4e-16 58.9 9.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 KFM03651.1 - 3.9e-10 39.3 6.5 7.2e-10 38.4 4.5 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.4 KFM03651.1 - 3.8e-09 36.0 15.6 7e-09 35.1 10.8 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Flavi_NS4A PF01350.12 KFM03651.1 - 0.018 14.5 0.8 6.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A CcmH PF03918.9 KFM03651.1 - 0.054 12.4 0.1 0.16 10.9 0.0 1.8 2 0 0 2 2 2 0 Cytochrome C biogenesis protein PepSY_TM_2 PF13703.1 KFM03651.1 - 0.2 11.8 8.8 0.16 12.1 1.0 3.0 3 0 0 3 3 3 0 PepSY-associated TM helix LIM PF00412.17 KFM03652.1 - 7.1e-39 131.6 28.0 2.6e-13 49.7 2.6 3.3 3 0 0 3 3 3 3 LIM domain PDZ PF00595.19 KFM03652.1 - 4.5e-12 45.9 0.0 9.1e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM03652.1 - 0.019 14.8 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 PDZ domain Pkinase PF00069.20 KFM03653.1 - 2.5e-54 184.1 0.0 3.4e-54 183.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM03653.1 - 1.7e-38 132.1 0.0 2.3e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TGF_beta_GS PF08515.7 KFM03653.1 - 1.2e-15 56.5 0.3 2.7e-15 55.3 0.2 1.7 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.18 KFM03653.1 - 0.00089 19.8 0.7 0.0025 18.4 0.2 2.0 2 0 0 2 2 2 1 Activin types I and II receptor domain Kinase-like PF14531.1 KFM03653.1 - 0.052 12.4 0.0 4.7 6.0 0.0 2.1 2 0 0 2 2 2 0 Kinase-like LRRC37AB_C PF14914.1 KFM03653.1 - 0.1 11.9 0.0 0.25 10.7 0.0 1.6 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain APH PF01636.18 KFM03653.1 - 0.15 11.7 0.0 0.36 10.5 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family ZU5 PF00791.15 KFM03654.1 - 3.8e-38 129.2 0.1 7.3e-38 128.3 0.1 1.5 1 0 0 1 1 1 1 ZU5 domain Death PF00531.17 KFM03654.1 - 1.9e-13 49.9 0.0 3.5e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Death domain I-set PF07679.11 KFM03654.1 - 2.5e-12 46.4 1.8 5.2e-11 42.2 0.1 3.2 3 0 0 3 3 3 1 Immunoglobulin I-set domain TSP_1 PF00090.14 KFM03654.1 - 4.3e-10 39.5 29.4 7e-08 32.4 5.8 2.7 2 0 0 2 2 2 2 Thrombospondin type 1 domain Ig_2 PF13895.1 KFM03654.1 - 6.1e-09 35.8 3.7 6.6e-07 29.3 0.0 4.3 3 2 1 4 4 4 1 Immunoglobulin domain Ig_3 PF13927.1 KFM03654.1 - 4.9e-05 23.7 0.2 0.00093 19.6 0.0 3.1 3 0 0 3 3 3 1 Immunoglobulin domain V-set PF07686.12 KFM03654.1 - 0.00082 19.2 0.0 0.0032 17.3 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin V-set domain Arm PF00514.18 KFM03655.1 - 1.6e-33 113.3 14.8 2.2e-08 33.6 0.1 6.7 7 0 0 7 7 7 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFM03655.1 - 3.1e-09 36.9 5.1 0.04 14.1 0.0 4.8 2 2 1 3 3 3 3 HEAT repeats V-ATPase_H_N PF03224.9 KFM03655.1 - 0.00015 20.9 7.2 0.027 13.6 0.4 4.3 1 1 0 2 2 2 1 V-ATPase subunit H Atx10homo_assoc PF09759.4 KFM03655.1 - 0.00068 19.3 0.2 0.006 16.2 0.1 2.6 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.1 KFM03655.1 - 0.00075 19.9 6.8 2.2 8.8 0.0 4.9 6 0 0 6 6 6 1 HEAT-like repeat SNase PF00565.12 KFM03655.1 - 0.014 15.6 0.1 3 8.1 0.1 2.8 2 0 0 2 2 2 0 Staphylococcal nuclease homologue Nitr_red_bet_C PF14711.1 KFM03655.1 - 0.037 13.5 0.0 0.095 12.2 0.0 1.6 1 0 0 1 1 1 0 Respiratory nitrate reductase beta C-terminal HEAT PF02985.17 KFM03655.1 - 0.47 10.6 8.9 3.3 8.0 0.1 4.8 7 0 0 7 7 7 0 HEAT repeat DUF2435 PF10363.4 KFM03655.1 - 2.9 7.8 7.2 3.8 7.4 0.0 3.9 4 1 0 4 4 4 0 Protein of unknown function (DUF2435) Tetraspannin PF00335.15 KFM03656.1 - 1.1e-43 149.0 11.7 1.5e-43 148.6 8.1 1.2 1 0 0 1 1 1 1 Tetraspanin family YrvL PF14184.1 KFM03656.1 - 0.78 9.5 9.8 0.68 9.7 3.8 2.2 2 0 0 2 2 2 0 Regulatory protein YrvL Claudin_2 PF13903.1 KFM03656.1 - 9.5 5.8 9.5 3.3 7.3 3.2 2.1 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction IF4E PF01652.13 KFM03657.1 - 2.7e-58 196.1 0.2 3.2e-58 195.9 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Peptidase_M24 PF00557.19 KFM03658.1 - 1.6e-47 161.7 0.4 2e-47 161.4 0.3 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Pyr_redox_dim PF02852.17 KFM03658.1 - 0.031 14.2 0.1 0.057 13.4 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain ADH_N PF08240.7 KFM03659.1 - 7.5e-27 93.2 1.8 2.4e-26 91.6 1.2 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFM03659.1 - 1.1e-22 80.0 0.8 1.9e-22 79.2 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFM03659.1 - 0.0069 17.2 0.0 0.017 15.9 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 KFM03659.1 - 0.053 12.9 0.7 0.1 11.9 0.5 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 KFM03659.1 - 0.082 12.0 0.1 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_N PF08240.7 KFM03660.1 - 2e-26 91.9 3.3 5e-26 90.5 2.3 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFM03660.1 - 3.9e-26 91.1 0.2 8e-26 90.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFM03660.1 - 0.0088 16.9 0.0 0.018 15.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 KFM03660.1 - 0.033 13.5 0.2 0.063 12.6 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 KFM03660.1 - 0.061 12.4 0.0 0.097 11.8 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.16 KFM03660.1 - 0.21 11.4 1.3 0.65 9.8 0.9 1.8 1 0 0 1 1 1 0 ThiF family SPATIAL PF15256.1 KFM03661.1 - 8e-19 68.4 4.1 1.4e-18 67.7 2.9 1.4 1 1 0 1 1 1 1 SPATIAL tRNA_m1G_MT PF01746.16 KFM03662.1 - 2.1e-48 164.4 0.5 3.6e-48 163.6 0.4 1.4 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase DUF4355 PF14265.1 KFM03662.1 - 0.0019 18.1 11.0 0.0044 16.9 7.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4355) NARP1 PF12569.3 KFM03662.1 - 0.035 12.8 9.6 0.05 12.3 6.7 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Vitellogenin_N PF01347.17 KFM03663.1 - 3.7e-62 210.4 7.5 4.4e-62 210.2 5.2 1.1 1 0 0 1 1 1 1 Lipoprotein amino terminal region HEAT_2 PF13646.1 KFM03663.1 - 0.12 12.6 2.3 0.62 10.3 0.3 2.6 1 1 1 2 2 2 0 HEAT repeats SH2 PF00017.19 KFM03664.1 - 4.2e-20 71.3 0.5 7.7e-20 70.4 0.3 1.5 1 0 0 1 1 1 1 SH2 domain PH PF00169.24 KFM03664.1 - 7.5e-16 58.2 1.8 8.7e-16 58.0 0.4 1.7 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 KFM03664.1 - 3.7e-05 23.9 1.5 0.00013 22.1 0.5 2.3 2 1 0 2 2 2 1 Pleckstrin homology domain MAPKK1_Int PF08923.5 KFM03665.1 - 1.8e-45 153.4 0.0 2e-45 153.2 0.0 1.0 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting DnaJ PF00226.26 KFM03666.1 - 3.6e-27 93.8 0.9 6.7e-27 93.0 0.6 1.5 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 KFM03666.1 - 3.4e-24 85.1 1.2 5.7e-24 84.4 0.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) Histone PF00125.19 KFM03667.1 - 2e-22 79.1 0.1 2.4e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFM03667.1 - 0.0049 16.9 0.0 0.0066 16.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Sel1 PF08238.7 KFM03668.1 - 8.3e-09 35.8 1.6 3.1e-08 33.9 0.3 2.4 2 1 0 2 2 2 1 Sel1 repeat Fe_hyd_lg_C PF02906.9 KFM03668.1 - 0.031 13.5 0.0 0.034 13.3 0.0 1.1 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain Endomucin PF07010.7 KFM03669.1 - 3.9e-21 75.5 0.1 4.4e-21 75.3 0.1 1.0 1 0 0 1 1 1 1 Endomucin DUF1628 PF07790.6 KFM03669.1 - 0.089 13.5 0.1 0.11 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1628) DUF4234 PF14018.1 KFM03669.1 - 0.12 12.1 3.4 0.1 12.3 0.9 1.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4234) Metallophos PF00149.23 KFM03670.1 - 7.7e-41 139.6 0.5 1.2e-40 139.0 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DBB PF14545.1 KFM03671.1 - 4e-21 75.0 0.0 6.5e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 Dof, BCAP, and BANK (DBB) motif, Ank_3 PF13606.1 KFM03671.1 - 0.058 13.6 0.1 0.17 12.2 0.1 1.8 1 0 0 1 1 1 0 Ankyrin repeat Ank_2 PF12796.2 KFM03671.1 - 0.061 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFM03671.1 - 0.1 12.8 0.1 0.32 11.2 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeats (many copies) RNA_pol_Rpb2_45 PF10385.4 KFM03671.1 - 0.14 11.9 0.4 0.45 10.3 0.1 1.9 2 0 0 2 2 2 0 RNA polymerase beta subunit external 1 domain RHD PF00554.17 KFM03673.1 - 7.2e-71 237.3 0.0 1.5e-70 236.2 0.0 1.6 1 0 0 1 1 1 1 Rel homology domain (RHD) Ank_2 PF12796.2 KFM03673.1 - 2.8e-46 155.7 23.8 4.3e-15 55.8 0.7 4.4 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 KFM03673.1 - 8.1e-35 116.9 13.9 6.3e-08 32.0 0.0 7.6 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 KFM03673.1 - 2.2e-26 91.7 4.9 7.9e-10 38.9 0.1 5.5 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM03673.1 - 8.9e-24 81.2 9.7 0.0016 18.5 0.3 7.5 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 KFM03673.1 - 1e-22 79.6 8.8 1.5e-07 31.4 0.2 5.9 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Death PF00531.17 KFM03673.1 - 1.3e-12 47.2 0.0 3.6e-12 45.8 0.0 1.8 1 0 0 1 1 1 1 Death domain Glyco_hydro_2_N PF02837.13 KFM03674.1 - 5.5e-09 35.7 0.0 1.6e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KFM03674.1 - 1.8e-08 33.6 0.1 3.8e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain VP40 PF07447.7 KFM03674.1 - 0.026 13.5 0.1 0.15 11.1 0.0 2.0 1 1 1 2 2 2 0 Matrix protein VP40 UQ_con PF00179.21 KFM03675.1 - 2.9e-51 172.5 0.0 3.3e-51 172.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFM03675.1 - 0.00022 20.9 0.0 0.00025 20.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KFM03675.1 - 0.0025 17.7 0.0 0.0034 17.2 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KFM03675.1 - 0.044 13.4 0.0 0.068 12.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain zf-CDGSH PF09360.5 KFM03676.1 - 2.9e-10 39.7 0.5 4.9e-10 39.0 0.4 1.4 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type MitoNEET_N PF10660.4 KFM03676.1 - 5.3e-10 38.9 0.0 7.5e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Iron-containing outer mitochondrial membrane protein N-terminus DUF1154 PF06631.6 KFM03676.1 - 1.6 8.4 0.0 1.6 8.4 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1154) Na_H_Exchanger PF00999.16 KFM03677.1 - 3.2e-26 91.7 39.7 5e-26 91.1 27.6 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family adh_short_C2 PF13561.1 KFM03678.1 - 7e-27 94.7 0.1 7.8e-27 94.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFM03678.1 - 5.1e-18 65.5 0.0 6.8e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFM03678.1 - 0.0017 18.0 0.0 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 KFM03678.1 - 0.027 13.4 0.0 0.044 12.7 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase PD-C2-AF1 PF09310.5 KFM03678.1 - 0.035 13.2 0.0 0.048 12.8 0.0 1.2 1 0 0 1 1 1 0 POU domain, class 2, associating factor 1 Transglut_core2 PF13369.1 KFM03678.1 - 0.044 13.2 0.0 0.078 12.4 0.0 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily DUF1776 PF08643.5 KFM03678.1 - 0.044 12.9 0.3 0.28 10.2 0.0 1.9 1 1 1 2 2 2 0 Fungal family of unknown function (DUF1776) DUF2325 PF10087.4 KFM03678.1 - 0.068 13.0 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) Radial_spoke PF04712.7 KFM03679.1 - 1.1e-180 601.6 10.2 1.1e-180 601.6 7.0 1.9 1 1 1 2 2 2 1 Radial spokehead-like protein TBPIP PF07106.8 KFM03679.1 - 0.0097 15.4 0.1 0.026 14.0 0.0 1.7 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) 7tm_1 PF00001.16 KFM03680.1 - 1.7e-63 214.1 20.1 2.2e-63 213.8 13.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM03680.1 - 9.4e-11 41.3 19.7 1.2e-10 40.9 13.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx PsbX PF06596.6 KFM03680.1 - 1.6 8.4 8.8 0.061 13.0 1.2 2.4 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) DUF912 PF06024.7 KFM03680.1 - 3.2 7.8 7.2 1.9 8.6 0.1 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Tet_JBP PF12851.2 KFM03682.1 - 4.2e-85 283.2 0.3 4.2e-85 283.2 0.2 1.9 2 0 0 2 2 2 1 Oxygenase domain of the 2OGFeDO superfamily Pyrophosphatase PF00719.14 KFM03683.1 - 1.5e-53 180.4 0.5 1.9e-53 180.0 0.4 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase RhoGEF PF00621.15 KFM03684.1 - 1.6e-21 77.0 0.7 2.2e-21 76.5 0.5 1.2 1 0 0 1 1 1 1 RhoGEF domain HAUS6_N PF14661.1 KFM03684.1 - 0.15 11.4 0.7 0.33 10.2 0.3 1.7 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus BAR PF03114.13 KFM03685.1 - 9.8e-29 100.4 4.4 2e-28 99.4 3.1 1.5 1 0 0 1 1 1 1 BAR domain RhoGEF PF00621.15 KFM03685.1 - 4.3e-14 52.7 0.1 4.3e-14 52.7 0.1 2.7 3 1 0 3 3 3 1 RhoGEF domain SH3_2 PF07653.12 KFM03685.1 - 1.4e-12 46.9 0.0 2e-05 23.9 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.1 KFM03685.1 - 1.4e-10 40.5 0.2 7.4e-10 38.2 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 KFM03685.1 - 6e-10 38.3 1.5 2.6e-08 33.0 0.0 2.8 3 0 0 3 3 3 1 SH3 domain PHD PF00628.24 KFM03686.1 - 1.2e-09 37.7 9.3 1.9e-09 37.0 6.5 1.4 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.17 KFM03686.1 - 2.9e-05 23.7 3.3 2.9e-05 23.7 2.3 2.0 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 KFM03686.1 - 0.00018 21.1 3.4 0.00018 21.1 2.4 1.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 PHD_2 PF13831.1 KFM03686.1 - 0.00028 20.1 5.9 0.00059 19.1 4.1 1.6 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.1 KFM03686.1 - 0.0013 18.0 3.4 0.003 16.8 2.4 1.6 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain DUF4206 PF13901.1 KFM03686.1 - 0.004 16.7 4.7 0.0067 16.0 3.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4206) Cytochrom_c3_2 PF14537.1 KFM03686.1 - 0.18 12.1 9.0 0.21 11.9 4.5 2.3 1 1 1 2 2 2 0 Cytochrome c3 FYVE_2 PF02318.11 KFM03686.1 - 0.22 11.4 5.5 0.43 10.4 3.8 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Cytochrome_C7 PF14522.1 KFM03686.1 - 0.65 9.6 7.4 2 8.1 3.6 2.4 1 1 1 2 2 2 0 Cytochrome c7 zf-RING_2 PF13639.1 KFM03686.1 - 4 7.3 9.4 10 6.0 6.5 1.7 1 1 0 1 1 1 0 Ring finger domain Methyltransf_32 PF13679.1 KFM03687.1 - 4.3e-13 49.1 0.2 8.3e-13 48.2 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFM03687.1 - 5.2e-09 35.8 0.1 9.1e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFM03687.1 - 6.3e-07 29.9 0.1 3.2e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain GidB PF02527.10 KFM03687.1 - 5.8e-05 22.3 0.0 0.00011 21.4 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G TRM13 PF05206.9 KFM03687.1 - 0.0002 20.6 1.0 0.39 9.9 0.5 2.7 1 1 0 2 2 2 2 Methyltransferase TRM13 MTS PF05175.9 KFM03687.1 - 0.00032 20.1 0.0 0.00057 19.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 KFM03687.1 - 0.0024 16.9 0.0 0.0041 16.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 KFM03687.1 - 0.01 15.8 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain GST_C_2 PF13410.1 KFM03687.1 - 0.01 15.7 0.0 0.074 12.9 0.0 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Ubie_methyltran PF01209.13 KFM03687.1 - 0.014 14.4 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 KFM03687.1 - 0.065 12.6 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_25 PF13649.1 KFM03687.1 - 0.09 13.1 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain GST_C PF00043.20 KFM03687.1 - 0.13 12.3 0.0 1.1 9.3 0.0 2.5 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain MAM PF00629.18 KFM03688.1 - 1.4e-24 86.6 0.0 3e-24 85.6 0.0 1.6 1 1 0 1 1 1 1 MAM domain EGF_CA PF07645.10 KFM03688.1 - 5.5e-24 83.8 63.0 1.6e-10 40.7 2.6 5.6 4 1 1 5 5 5 3 Calcium-binding EGF domain cEGF PF12662.2 KFM03688.1 - 9.5e-17 60.3 42.6 8.4e-06 25.3 0.4 5.9 5 0 0 5 5 5 5 Complement Clr-like EGF-like FXa_inhibition PF14670.1 KFM03688.1 - 3.5e-11 43.0 72.4 4.4e-06 26.7 4.6 5.5 4 1 1 5 5 5 4 Coagulation Factor Xa inhibitory site EGF PF00008.22 KFM03688.1 - 4e-06 26.6 72.0 0.015 15.2 1.0 6.2 5 1 0 5 5 5 5 EGF-like domain EGF_3 PF12947.2 KFM03688.1 - 2.1e-05 24.4 65.1 3.3e-05 23.7 9.0 5.9 5 1 0 5 5 5 3 EGF domain hEGF PF12661.2 KFM03688.1 - 0.017 15.1 4.8 0.017 15.1 3.3 6.2 6 0 0 6 6 6 0 Human growth factor-like EGF EGF_MSP1_1 PF12946.2 KFM03688.1 - 0.17 11.6 36.6 0.08 12.7 4.8 4.7 4 0 0 4 4 4 0 MSP1 EGF domain 1 RabGAP-TBC PF00566.13 KFM03689.1 - 2.4e-47 161.1 0.2 3.7e-47 160.5 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.20 KFM03689.1 - 2.4e-35 121.9 0.0 3.5e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM03689.1 - 5.5e-26 91.1 0.0 9.2e-26 90.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Rhodanese PF00581.15 KFM03689.1 - 6.1e-16 58.7 0.0 1.1e-15 57.9 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Kinase-like PF14531.1 KFM03689.1 - 1.7e-05 23.9 0.0 2.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like tRNA_bind PF01588.15 KFM03690.1 - 1.3e-30 105.1 0.6 2.3e-30 104.2 0.1 1.7 2 0 0 2 2 2 1 Putative tRNA binding domain NUDE_C PF04880.8 KFM03690.1 - 0.00045 20.6 1.5 0.00071 19.9 0.6 1.4 1 1 0 1 1 1 1 NUDE protein, C-terminal conserved region DUF904 PF06005.7 KFM03690.1 - 0.023 15.0 11.1 0.023 15.0 7.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Ribosomal_60s PF00428.14 KFM03690.1 - 0.13 12.6 6.8 0.53 10.7 4.6 2.2 2 1 0 2 2 2 0 60s Acidic ribosomal protein Rad9_Rad53_bind PF08605.5 KFM03690.1 - 0.2 11.4 1.3 13 5.5 0.0 2.3 2 0 0 2 2 2 0 Fungal Rad9-like Rad53-binding DUF972 PF06156.8 KFM03690.1 - 1.6 9.1 10.1 0.066 13.5 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) AIG1 PF04548.11 KFM03691.1 - 6.9e-26 90.6 0.0 9.3e-26 90.2 0.0 1.1 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 KFM03691.1 - 0.0033 17.3 0.0 0.0049 16.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 KFM03691.1 - 0.0041 16.6 0.1 0.0064 15.9 0.1 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family Septin PF00735.13 KFM03691.1 - 0.0047 15.9 0.0 0.0066 15.4 0.0 1.2 1 0 0 1 1 1 1 Septin Prokineticin PF06607.6 KFM03692.1 - 0.0019 18.2 7.2 0.0023 17.9 5.0 1.1 1 0 0 1 1 1 1 Prokineticin PilI PF10623.4 KFM03692.1 - 0.15 12.0 1.8 0.17 11.8 0.5 1.7 1 1 0 1 1 1 0 Plasmid conjugative transfer protein PilI Toxin_21 PF08091.6 KFM03692.1 - 2.5 7.9 12.4 0.062 13.0 3.2 2.2 2 1 0 2 2 2 0 Spider insecticidal peptide CarbpepA_inh PF02977.10 KFM03692.1 - 4.4 6.9 9.9 0.089 12.3 1.9 1.8 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor APS_kinase PF01583.15 KFM03693.1 - 8.7e-75 249.6 0.0 1.4e-74 248.9 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.12 KFM03693.1 - 2.9e-69 232.6 0.1 4.2e-69 232.1 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 KFM03693.1 - 5.3e-49 165.6 0.0 1.1e-48 164.6 0.0 1.6 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.1 KFM03693.1 - 1e-09 38.3 0.0 2e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFM03693.1 - 1.2e-06 29.3 0.2 6.7e-06 26.9 0.0 2.2 2 2 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KFM03693.1 - 0.00034 20.9 0.0 0.0012 19.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 KFM03693.1 - 0.014 14.6 0.0 0.026 13.7 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 KFM03693.1 - 0.017 14.2 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Thymidylate_kin PF02223.12 KFM03693.1 - 0.02 14.2 0.0 0.039 13.3 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase 6PF2K PF01591.13 KFM03693.1 - 0.028 13.4 0.0 0.053 12.5 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_28 PF13521.1 KFM03693.1 - 0.06 13.3 0.2 0.57 10.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain DUF258 PF03193.11 KFM03693.1 - 0.086 12.0 0.0 0.23 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 KFM03693.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain PAP2_C PF14360.1 KFM03694.1 - 2.8e-28 98.0 13.4 2.8e-28 98.0 9.3 2.3 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.16 KFM03694.1 - 1e-05 25.2 12.1 2.5e-05 23.9 8.3 1.9 1 1 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.1 KFM03694.1 - 0.00028 20.4 7.9 0.00028 20.4 5.5 1.9 2 1 0 2 2 2 1 PAP2 superfamily p450 PF00067.17 KFM03695.1 - 1.4e-105 353.4 0.2 1.6e-105 353.3 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 3HCDH_N PF02737.13 KFM03696.1 - 3.4e-53 179.9 3.2 4.4e-53 179.5 2.2 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KFM03696.1 - 3.4e-35 120.3 0.0 8e-35 119.1 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DHC_N2 PF08393.8 KFM03696.1 - 0.034 12.6 0.1 0.044 12.2 0.1 1.1 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 CTNNB1_binding PF08347.6 KFM03697.1 - 7e-46 157.0 10.4 7e-46 157.0 7.2 2.3 2 1 0 2 2 2 1 N-terminal CTNNB1 binding HMG_box PF00505.14 KFM03697.1 - 8.5e-22 77.2 0.7 8.5e-22 77.2 0.5 2.5 3 1 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFM03697.1 - 2.2e-08 34.3 0.5 6.4e-08 32.8 0.3 1.8 1 0 0 1 1 1 1 HMG-box domain MAT_Alpha1 PF04769.7 KFM03697.1 - 0.029 13.7 0.1 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 Ribosomal_L34e PF01199.13 KFM03698.1 - 9.2e-38 128.3 8.1 1.1e-37 128.0 5.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e OST3_OST6 PF04756.8 KFM03699.1 - 1.3e-39 135.3 1.2 1.6e-39 134.9 0.8 1.1 1 0 0 1 1 1 1 OST3 / OST6 family RVT_1 PF00078.22 KFM03700.1 - 0.099 11.9 0.0 0.19 11.0 0.0 1.4 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Aminotran_3 PF00202.16 KFM03701.1 - 1.1e-77 261.1 0.0 1.7e-77 260.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-III DUF607 PF04678.8 KFM03702.1 - 6.4e-59 198.8 2.5 8.3e-59 198.5 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF607 NDUF_C2 PF06374.6 KFM03702.1 - 0.0043 17.0 0.2 0.01 15.8 0.1 1.7 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) DUF2346 PF09803.4 KFM03702.1 - 4.6 7.1 7.6 0.77 9.6 0.3 2.6 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2346) Peptidase_C14 PF00656.17 KFM03703.1 - 5.7e-51 173.5 0.1 6.8e-51 173.3 0.1 1.0 1 0 0 1 1 1 1 Caspase domain PLA2G12 PF06951.6 KFM03704.1 - 4.7e-65 218.7 10.0 5.2e-65 218.5 6.9 1.0 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) ATP-gua_PtransN PF02807.10 KFM03704.1 - 0.085 13.0 0.2 0.12 12.5 0.2 1.2 1 0 0 1 1 1 0 ATP:guanido phosphotransferase, N-terminal domain Phospholip_A2_2 PF05826.7 KFM03704.1 - 6.8 6.7 15.5 7.3e+02 0.1 9.3 2.5 1 1 0 1 1 1 0 Phospholipase A2 Gar1 PF04410.9 KFM03705.1 - 2.9e-42 143.7 0.2 2.9e-42 143.7 0.1 1.9 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region 7tm_1 PF00001.16 KFM03706.1 - 6.4e-48 163.1 14.9 7.6e-48 162.8 10.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM03706.1 - 2.1e-12 46.7 12.3 2.5e-12 46.4 8.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF4117 PF13491.1 KFM03706.1 - 1.7 8.1 8.2 0.082 12.3 1.4 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4117) LRR_8 PF13855.1 KFM03707.1 - 1.5e-21 75.9 3.9 2.1e-14 52.9 1.3 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 KFM03707.1 - 8.5e-19 66.7 12.0 6.7e-09 35.1 1.8 3.5 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM03707.1 - 2e-11 42.2 6.5 0.0067 16.3 0.1 5.1 5 0 0 5 5 5 3 Leucine Rich Repeat Ig_2 PF13895.1 KFM03707.1 - 2.9e-11 43.3 0.1 8.5e-11 41.8 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.11 KFM03707.1 - 2.9e-10 39.8 0.0 5.8e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_6 PF13516.1 KFM03707.1 - 6.8e-08 31.8 1.9 0.086 12.9 0.0 4.0 3 0 0 3 3 3 2 Leucine Rich repeat LRR_7 PF13504.1 KFM03707.1 - 1.2e-07 30.7 10.8 0.0088 16.0 0.2 4.2 4 0 0 4 4 3 2 Leucine rich repeat LRR_5 PF13306.1 KFM03707.1 - 3.6e-06 26.7 0.0 6.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) Ig_3 PF13927.1 KFM03707.1 - 6.6e-06 26.5 1.9 3.4e-05 24.2 0.4 2.6 2 1 0 2 2 2 1 Immunoglobulin domain ig PF00047.20 KFM03707.1 - 0.00023 21.2 0.0 0.00046 20.2 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFM03707.1 - 0.0076 16.1 0.0 0.062 13.1 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin V-set domain LRRNT PF01462.13 KFM03707.1 - 0.062 12.8 7.9 0.34 10.4 1.4 3.6 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain AmiS_UreI PF02293.10 KFM03707.1 - 0.14 11.8 0.0 6.8 6.3 0.0 2.2 2 0 0 2 2 2 0 AmiS/UreI family transporter Ldl_recept_b PF00058.12 KFM03708.1 - 2.8e-46 155.5 15.4 2.8e-11 43.5 0.0 9.2 10 0 0 10 10 10 6 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.1 KFM03708.1 - 5.2e-35 119.2 149.1 1.3e-08 34.7 4.6 11.5 11 0 0 11 11 11 8 Coagulation Factor Xa inhibitory site cEGF PF12662.2 KFM03708.1 - 1.6e-30 104.3 75.7 2.4e-05 23.8 3.2 11.5 11 0 0 11 11 11 8 Complement Clr-like EGF-like EGF_CA PF07645.10 KFM03708.1 - 4.9e-21 74.4 51.5 6.1e-08 32.5 7.4 11.4 11 0 0 11 11 11 5 Calcium-binding EGF domain EGF PF00008.22 KFM03708.1 - 3.4e-19 68.4 117.4 8.5e-05 22.4 4.0 11.0 10 0 0 10 10 10 8 EGF-like domain EGF_3 PF12947.2 KFM03708.1 - 9.8e-17 60.6 125.2 3.9e-06 26.7 7.8 10.8 10 0 0 10 10 10 6 EGF domain ELO PF01151.13 KFM03709.1 - 9.6e-66 221.6 23.2 1.1e-65 221.4 16.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Peptidase_M1 PF01433.15 KFM03710.1 - 3e-142 474.3 0.8 5.1e-142 473.5 0.5 1.4 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 KFM03710.1 - 5.1e-50 170.5 0.5 1.4e-49 169.1 0.3 1.8 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KFM03710.1 - 3.6e-21 75.5 0.0 7.9e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily DUF1570 PF07607.6 KFM03710.1 - 0.002 18.1 1.1 0.0059 16.5 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1570) Homeobox PF00046.24 KFM03711.1 - 8.2e-23 79.7 9.2 1.4e-22 79.0 6.4 1.4 1 0 0 1 1 1 1 Homeobox domain OAR PF03826.12 KFM03711.1 - 6.3e-10 38.2 0.9 6.3e-10 38.2 0.6 2.0 2 0 0 2 2 2 1 OAR domain Homeobox_KN PF05920.6 KFM03711.1 - 0.003 17.2 0.7 0.0099 15.5 0.5 1.9 1 0 0 1 1 1 1 Homeobox KN domain HTH_32 PF13565.1 KFM03711.1 - 0.55 11.0 4.3 0.16 12.7 0.6 1.8 1 1 1 2 2 2 0 Homeodomain-like domain DUF4605 PF15378.1 KFM03712.1 - 1.1e-27 95.5 6.1 1.1e-27 95.5 4.3 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4605) PHO4 PF01384.15 KFM03713.1 - 5.2e-129 429.5 0.0 1.1e-128 428.4 0.0 1.5 1 1 0 1 1 1 1 Phosphate transporter family Vpu PF00558.14 KFM03713.1 - 0.023 14.2 0.2 0.023 14.2 0.2 2.2 2 0 0 2 2 2 0 Vpu protein Syndecan PF01034.15 KFM03713.1 - 0.37 10.4 3.1 4.4 7.0 0.1 3.4 2 0 0 2 2 2 0 Syndecan domain UPF0697 PF15117.1 KFM03714.1 - 4.2e-32 109.8 1.5 4.6e-32 109.7 1.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0697 Pkinase_Tyr PF07714.12 KFM03715.1 - 8.2e-10 38.1 0.1 1.1e-08 34.4 0.1 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 KFM03715.1 - 1.9e-07 30.5 0.1 2e-05 23.8 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain PIP49_C PF12260.3 KFM03715.1 - 0.0058 16.0 0.0 0.0088 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 DUF1624 PF07786.7 KFM03716.1 - 1e-07 31.5 0.6 1e-07 31.5 0.4 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1624) TPR_19 PF14559.1 KFM03717.1 - 0.0097 16.2 0.1 0.037 14.3 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 KFM03717.1 - 0.017 14.7 0.0 0.048 13.3 0.0 1.8 1 0 0 1 1 1 0 TPR repeat Apc3 PF12895.2 KFM03717.1 - 0.05 13.7 0.6 0.23 11.6 0.1 2.3 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 CHGN PF05679.11 KFM03718.1 - 3.1e-56 191.1 0.0 4e-56 190.7 0.0 1.2 1 1 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_tranf_2_2 PF10111.4 KFM03718.1 - 5.9e-11 41.9 0.1 1e-10 41.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 KFM03718.1 - 3.9e-10 39.0 0.8 8.4e-10 37.9 0.6 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glycos_transf_2 PF00535.21 KFM03718.1 - 0.00085 19.0 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Mod_r PF07200.8 KFM03718.1 - 0.00098 19.0 1.3 0.0025 17.7 0.9 1.6 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein LUC7 PF03194.10 KFM03718.1 - 0.032 13.7 1.4 0.055 12.9 1.0 1.3 1 0 0 1 1 1 0 LUC7 N_terminus IncA PF04156.9 KFM03718.1 - 0.057 13.0 0.2 0.1 12.2 0.2 1.3 1 0 0 1 1 1 0 IncA protein THOC7 PF05615.8 KFM03718.1 - 0.22 11.7 4.5 0.1 12.8 0.8 2.1 2 0 0 2 2 2 0 Tho complex subunit 7 YlqD PF11068.3 KFM03718.1 - 0.5 10.4 5.8 0.076 13.0 0.9 1.9 2 0 0 2 2 2 0 YlqD protein SH2 PF00017.19 KFM03719.1 - 4.1e-13 48.9 0.1 1e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 SH2 domain TetM_leader PF08076.6 KFM03719.1 - 0.12 11.9 0.1 0.27 10.8 0.1 1.5 1 0 0 1 1 1 0 Tetracycline resistance determinant leader peptide Sulfotransfer_1 PF00685.22 KFM03720.1 - 3.1e-90 302.0 0.1 3.5e-90 301.8 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 KFM03720.1 - 1.3e-07 32.6 0.0 2.4e-07 31.7 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase family Sulphotransf PF09037.5 KFM03720.1 - 0.0015 18.0 0.0 0.069 12.6 0.0 2.3 2 0 0 2 2 2 1 Stf0 sulphotransferase HTH_Tnp_Tc3_2 PF01498.13 KFM03720.1 - 0.071 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Transposase Sulfotransfer_1 PF00685.22 KFM03721.1 - 1.4e-40 139.2 0.0 1.6e-40 139.0 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain UDPGT PF00201.13 KFM03722.1 - 7.4e-218 724.1 0.1 8.3e-218 723.9 0.1 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 KFM03722.1 - 2.8e-06 27.1 0.0 4.6e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 KFM03722.1 - 8.4e-06 25.1 0.0 0.00039 19.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 1 Glyco_trans_4_4 PF13579.1 KFM03722.1 - 0.026 14.6 0.0 0.064 13.3 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Pro_3_hydrox_C PF05373.6 KFM03722.1 - 0.081 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 L-proline 3-hydroxylase, C-terminal Leo1 PF04004.8 KFM03722.1 - 0.11 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Leo1-like protein YTH PF04146.10 KFM03723.1 - 5.4e-42 142.7 0.0 8.2e-42 142.1 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain ThiF PF00899.16 KFM03724.1 - 1.9e-49 167.0 0.0 9.3e-33 112.9 0.0 2.4 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 KFM03724.1 - 2.8e-33 113.2 1.4 5.9e-26 89.8 0.1 2.9 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 KFM03724.1 - 1.8e-29 102.4 0.0 3.4e-29 101.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 KFM03724.1 - 1.9e-22 78.3 3.5 1.5e-19 69.0 1.5 2.5 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site CENP-C_C PF11699.3 KFM03725.1 - 4.5e-27 93.8 0.4 8.5e-27 92.9 0.3 1.5 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 KFM03725.1 - 5.4e-06 25.8 0.0 1.6e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 Cupin domain Pkinase_Tyr PF07714.12 KFM03727.1 - 3.1e-98 327.9 0.0 3.6e-98 327.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM03727.1 - 3.1e-50 170.7 0.0 3.7e-50 170.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.1 KFM03727.1 - 1.4e-16 60.6 0.3 2.3e-16 59.9 0.2 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Kdo PF06293.9 KFM03727.1 - 0.027 13.5 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Steroid_dh PF02544.11 KFM03728.1 - 9.9e-20 70.8 6.2 9.9e-20 70.8 4.3 1.9 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase Latrophilin PF02354.11 KFM03729.1 - 1.6e-172 573.3 14.3 2.6e-172 572.6 9.9 1.3 1 0 0 1 1 1 1 Latrophilin Cytoplasmic C-terminal region OLF PF02191.11 KFM03729.1 - 5.9e-95 317.2 2.6 1.1e-94 316.3 1.8 1.5 1 0 0 1 1 1 1 Olfactomedin-like domain DUF3497 PF12003.3 KFM03729.1 - 3.2e-82 275.1 7.2 4.6e-82 274.6 5.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3497) 7tm_2 PF00002.19 KFM03729.1 - 2e-70 236.6 19.2 3.8e-70 235.7 13.3 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Gal_Lectin PF02140.13 KFM03729.1 - 2e-23 82.5 0.8 2e-23 82.5 0.5 2.1 2 0 0 2 2 2 1 Galactose binding lectin domain GPS PF01825.16 KFM03729.1 - 1.5e-15 56.9 9.0 3.5e-15 55.8 6.2 1.7 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain HRM PF02793.17 KFM03729.1 - 1.6e-07 31.2 0.7 4.4e-07 29.8 0.5 1.8 1 0 0 1 1 1 1 Hormone receptor domain Dicty_CAR PF05462.6 KFM03729.1 - 0.0025 16.7 14.9 0.0046 15.9 10.3 1.4 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor DUF3481 PF11980.3 KFM03729.1 - 0.057 13.2 0.3 1.4 8.8 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3481) Arg_repressor PF01316.16 KFM03733.1 - 0.0053 16.2 0.0 0.0099 15.4 0.0 1.4 1 0 0 1 1 1 1 Arginine repressor, DNA binding domain Keratin PF02422.11 KFM03734.1 - 7.8e-36 121.9 10.8 8.6e-36 121.8 7.5 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 KFM03736.1 - 5e-40 135.4 16.5 5.5e-40 135.2 11.4 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 KFM03738.1 - 1.1e-40 137.5 20.8 1.2e-40 137.3 14.4 1.0 1 0 0 1 1 1 1 Keratin KRAB PF01352.22 KFM03740.1 - 9.8e-22 76.1 0.2 1.1e-21 75.9 0.1 1.1 1 0 0 1 1 1 1 KRAB box Ets PF00178.17 KFM03741.1 - 8.7e-31 105.9 4.0 6e-30 103.2 0.6 2.4 2 0 0 2 2 2 1 Ets-domain SAM_PNT PF02198.11 KFM03741.1 - 4.9e-25 87.0 3.0 7.8e-25 86.4 1.6 1.8 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain Acetyltransf_2 PF00797.12 KFM03741.1 - 0.029 13.9 0.1 0.12 11.8 0.1 2.0 1 1 0 1 1 1 0 N-acetyltransferase Aldolase_II PF00596.16 KFM03742.1 - 1.9e-43 148.1 0.0 2.3e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain 2-oxoacid_dh PF00198.18 KFM03743.1 - 7.5e-79 264.2 0.2 9.3e-79 263.9 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KFM03743.1 - 7.5e-21 73.5 0.4 1.8e-20 72.3 0.3 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KFM03743.1 - 8.7e-12 44.4 0.0 2.3e-11 43.1 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 KFM03743.1 - 0.00013 21.5 0.0 0.044 13.4 0.0 3.0 1 1 1 2 2 2 2 Biotin-lipoyl like QRPTase_N PF02749.11 KFM03743.1 - 0.053 13.3 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain HlyD_2 PF12700.2 KFM03743.1 - 0.092 11.8 0.0 0.33 10.0 0.0 1.7 1 1 1 2 2 2 0 HlyD family secretion protein Xlink PF00193.12 KFM03744.1 - 4.5e-23 81.1 0.6 8.1e-23 80.3 0.1 1.7 2 0 0 2 2 2 1 Extracellular link domain SDF PF00375.13 KFM03745.1 - 1.9e-125 418.7 27.3 2.1e-125 418.5 18.9 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Trypsin PF00089.21 KFM03747.1 - 1.4e-36 126.1 0.0 2e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 Trypsin CUB PF00431.15 KFM03747.1 - 1e-24 86.6 0.3 2.3e-24 85.5 0.0 1.8 2 0 0 2 2 2 1 CUB domain Sushi PF00084.15 KFM03747.1 - 7.7e-16 58.1 9.9 8.1e-09 35.7 0.2 3.4 3 0 0 3 3 3 2 Sushi domain (SCR repeat) EGF PF00008.22 KFM03747.1 - 1.7e-07 31.0 5.0 1.7e-07 31.0 3.5 3.7 4 1 0 4 4 4 1 EGF-like domain EGF_2 PF07974.8 KFM03747.1 - 0.0021 18.2 7.9 0.0021 18.2 5.5 4.3 5 0 0 5 5 5 1 EGF-like domain hEGF PF12661.2 KFM03747.1 - 0.03 14.3 1.3 0.03 14.3 0.9 4.7 4 0 0 4 4 4 0 Human growth factor-like EGF Ldl_recept_a PF00057.13 KFM03748.1 - 8.9e-32 108.6 45.3 2e-11 43.6 6.9 3.3 3 0 0 3 3 3 3 Low-density lipoprotein receptor domain class A PspB PF06667.7 KFM03748.1 - 0.076 12.9 1.4 0.12 12.2 0.4 1.7 2 0 0 2 2 2 0 Phage shock protein B FixQ PF05545.6 KFM03748.1 - 0.11 12.1 0.1 0.19 11.3 0.1 1.2 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Bromodomain PF00439.20 KFM03749.1 - 2.2e-48 162.0 3.2 1.1e-23 82.9 0.1 2.5 2 0 0 2 2 2 2 Bromodomain YL1 PF05764.8 KFM03749.1 - 0.0032 17.0 22.0 0.0032 17.0 15.3 3.0 3 0 0 3 3 3 1 YL1 nuclear protein Katanin_con80 PF13925.1 KFM03749.1 - 0.15 11.7 2.3 0.15 11.7 0.5 1.8 2 0 0 2 2 2 0 con80 domain of Katanin Peptidase_S49_N PF08496.5 KFM03749.1 - 8.3 6.1 17.5 23 4.7 12.1 1.8 1 0 0 1 1 1 0 Peptidase family S49 N-terminal AKAP95 PF04988.7 KFM03750.1 - 2.8e-19 69.4 1.6 3e-19 69.3 1.1 1.0 1 0 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_2 PF12756.2 KFM03750.1 - 0.0013 18.7 0.1 0.0013 18.7 0.0 1.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.1 KFM03750.1 - 0.0036 17.4 2.0 0.005 17.0 1.4 1.3 1 0 0 1 1 1 1 C2H2-type zinc-finger domain zf-Di19 PF05605.7 KFM03750.1 - 0.0037 17.3 0.2 0.004 17.2 0.1 1.1 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 KFM03750.1 - 0.023 15.0 0.7 0.032 14.5 0.5 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger DUF3449 PF11931.3 KFM03750.1 - 0.029 13.8 0.3 0.029 13.8 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Sep15_SelM PF08806.6 KFM03750.1 - 0.12 12.1 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Sep15/SelM redox domain zf-C2HC_2 PF13913.1 KFM03750.1 - 0.17 11.5 0.9 0.51 10.0 0.6 1.8 1 1 0 1 1 1 0 zinc-finger of a C2HC-type Tis11B_N PF04553.7 KFM03751.1 - 0.055 13.6 0.5 0.092 12.9 0.4 1.4 1 0 0 1 1 1 0 Tis11B like protein, N terminus AKAP95 PF04988.7 KFM03752.1 - 3.5e-73 244.7 7.4 3.5e-73 244.7 5.2 1.8 2 0 0 2 2 2 1 A-kinase anchoring protein 95 (AKAP95) zf-met PF12874.2 KFM03752.1 - 7.4 6.9 7.1 0.6 10.4 0.6 2.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-FCS PF06467.9 KFM03753.1 - 5.9e-09 35.4 5.4 0.061 12.9 0.0 4.6 5 0 0 5 5 5 3 MYM-type Zinc finger with FCS sequence motif zf-C2H2 PF00096.21 KFM03753.1 - 2e-08 34.1 30.8 0.037 14.3 0.8 6.0 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM03753.1 - 4.1e-07 29.8 30.1 0.08 13.3 0.6 5.9 6 0 0 6 6 6 4 C2H2-type zinc finger AnfO_nitrog PF09582.5 KFM03753.1 - 1.5e-06 27.4 0.0 0.14 11.3 0.0 3.4 3 0 0 3 3 3 2 Iron only nitrogenase protein AnfO (AnfO_nitrog) zf-C2H2_jaz PF12171.3 KFM03753.1 - 2.8e-05 24.1 13.0 1.2 9.3 0.1 4.8 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFM03753.1 - 0.00042 20.3 5.9 23 5.1 0.0 5.1 5 0 0 5 5 5 0 C2H2 type zinc-finger (2 copies) OTT_1508_deam PF14441.1 KFM03753.1 - 0.1 12.3 0.4 0.41 10.4 0.0 2.2 2 0 0 2 2 2 0 OTT_1508-like deaminase zf-BED PF02892.10 KFM03753.1 - 0.43 10.3 11.1 19 5.1 0.0 5.0 5 0 0 5 5 5 0 BED zinc finger zf-C2H2_4 PF13894.1 KFM03754.1 - 9.2e-07 28.7 21.6 0.29 11.5 0.7 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.21 KFM03754.1 - 9.9e-06 25.6 25.0 0.0038 17.4 0.3 5.5 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 KFM03754.1 - 0.00032 20.7 28.0 0.18 12.1 0.3 5.5 5 0 0 5 5 5 3 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 KFM03754.1 - 0.013 15.6 11.2 0.32 11.1 1.5 4.6 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFM03754.1 - 0.02 14.9 17.6 1.8 8.6 0.1 5.2 4 1 0 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 KFM03754.1 - 2.4 8.1 8.9 1.3 8.9 0.5 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger p450 PF00067.17 KFM03755.1 - 2.3e-99 333.0 0.0 1.2e-98 330.6 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 PKD_channel PF08016.7 KFM03756.1 - 1.6e-10 40.0 15.0 2.4e-10 39.4 10.4 1.2 1 0 0 1 1 1 1 Polycystin cation channel zf-C2H2 PF00096.21 KFM03757.1 - 2e-09 37.2 0.2 0.0025 18.0 0.2 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM03757.1 - 1.1e-07 31.7 0.0 1.1e-07 31.7 0.0 2.3 3 0 0 3 3 2 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 KFM03757.1 - 1.3e-05 24.9 2.6 0.042 13.7 0.5 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM03757.1 - 0.00019 21.4 0.0 0.53 10.4 0.0 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KFM03757.1 - 0.006 16.8 1.2 2.7 8.5 0.5 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 KFM03757.1 - 0.016 15.3 0.2 0.35 11.1 0.1 2.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-UBP PF02148.14 KFM03757.1 - 0.019 15.0 1.0 2.7 8.1 0.1 2.0 1 1 1 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein LIM PF00412.17 KFM03757.1 - 0.019 15.0 0.4 0.025 14.6 0.3 1.3 1 1 0 1 1 1 0 LIM domain zf-AN1 PF01428.11 KFM03757.1 - 0.049 13.5 3.5 3.4 7.6 0.2 2.2 1 1 1 2 2 2 0 AN1-like Zinc finger XPA_N PF01286.13 KFM03757.1 - 0.052 13.2 4.5 0.7 9.6 0.0 2.1 2 0 0 2 2 2 0 XPA protein N-terminal zf-B_box PF00643.19 KFM03757.1 - 0.17 11.7 1.3 1.8 8.5 0.0 2.1 1 1 1 2 2 2 0 B-box zinc finger zf-MYND PF01753.13 KFM03757.1 - 0.34 10.8 2.4 4.8 7.1 0.1 2.1 1 1 0 2 2 2 0 MYND finger IBR PF01485.16 KFM03757.1 - 0.5 10.2 2.8 18 5.2 2.3 2.0 1 1 0 1 1 1 0 IBR domain Zn-ribbon_8 PF09723.5 KFM03757.1 - 0.64 10.0 3.7 23 5.0 2.7 2.1 1 1 0 1 1 1 0 Zinc ribbon domain FYVE PF01363.16 KFM03757.1 - 0.72 9.7 3.3 6.4 6.7 2.3 2.0 1 1 0 1 1 1 0 FYVE zinc finger zf-RING_3 PF14369.1 KFM03757.1 - 0.92 9.5 3.9 6.3 6.8 0.5 2.2 1 1 1 2 2 2 0 zinc-finger Zn_ribbon_recom PF13408.1 KFM03757.1 - 1.1 9.5 3.2 15 5.9 0.2 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain RRN7 PF11781.3 KFM03757.1 - 1.4 8.4 4.5 1.9 8.0 0.1 2.4 2 1 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-trcl PF13451.1 KFM03757.1 - 1.5 8.5 4.6 1.6 8.4 0.0 2.1 2 0 0 2 2 2 0 Probable zinc-binding domain zinc_ribbon_2 PF13240.1 KFM03757.1 - 2.1 7.9 5.9 5.2 6.6 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain YhfH PF14149.1 KFM03757.1 - 6.6 6.6 6.5 4.9 7.0 0.1 2.1 2 0 0 2 2 2 0 YhfH-like protein RhoGAP PF00620.22 KFM03758.1 - 2.8e-45 153.6 0.0 4.4e-45 152.9 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain A2M_comp PF07678.9 KFM03759.1 - 1.1e-47 162.4 0.0 1.2e-47 162.1 0.0 1.0 1 0 0 1 1 1 1 A-macroglobulin complement component Prenyltrans_2 PF13249.1 KFM03759.1 - 0.0002 21.7 0.0 0.035 14.5 0.0 2.5 1 1 1 2 2 2 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 KFM03759.1 - 0.0081 16.1 0.0 0.033 14.2 0.0 1.6 1 1 1 2 2 2 2 Prenyltransferase-like Pkinase PF00069.20 KFM03760.1 - 1.1e-73 247.5 0.0 1.4e-73 247.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM03760.1 - 1.2e-35 122.8 0.3 5.6e-35 120.6 0.2 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase GCM PF03615.10 KFM03761.1 - 6.4e-78 259.2 1.6 1.1e-77 258.5 1.1 1.3 1 0 0 1 1 1 1 GCM motif protein ELO PF01151.13 KFM03762.1 - 4.9e-61 206.2 22.7 5.6e-61 206.0 15.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF3513 PF12026.3 KFM03763.1 - 2.1e-89 298.6 5.9 5.3e-89 297.3 4.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3513) Serine_rich PF08824.5 KFM03763.1 - 3.1e-60 202.5 4.2 7.2e-60 201.3 2.9 1.6 1 0 0 1 1 1 1 Serine rich protein interaction domain SH3_9 PF14604.1 KFM03763.1 - 5.9e-14 51.3 0.0 1.1e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM03763.1 - 3.7e-11 42.2 0.0 6.6e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFM03763.1 - 4.3e-11 42.1 0.0 7.6e-11 41.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Tmemb_170 PF10190.4 KFM03764.1 - 3e-47 158.9 10.6 3.3e-47 158.8 7.4 1.0 1 0 0 1 1 1 1 Putative transmembrane protein 170 DUF1691 PF07950.6 KFM03764.1 - 0.079 12.8 1.6 0.092 12.6 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1691) Sdh_cyt PF01127.17 KFM03764.1 - 1.5 8.6 9.5 0.41 10.4 4.3 1.7 1 1 1 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF3353 PF11833.3 KFM03764.1 - 2.2 7.7 5.3 4.6 6.6 3.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3353) Far-17a_AIG1 PF04750.9 KFM03765.1 - 6.3e-59 198.5 17.4 7.2e-59 198.3 12.1 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein DUF2306 PF10067.4 KFM03765.1 - 3.1 7.9 9.4 4.9 7.3 0.0 3.3 3 0 0 3 3 3 0 Predicted membrane protein (DUF2306) zf-C2H2 PF00096.21 KFM03766.1 - 8.6e-18 63.5 45.3 0.00019 21.5 1.1 6.1 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM03766.1 - 2.2e-10 40.3 11.3 1.5e-07 31.3 0.4 6.2 6 0 0 6 6 6 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFM03766.1 - 5.3e-09 35.9 40.0 0.0072 16.4 1.0 5.9 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KFM03766.1 - 3.9e-05 23.6 35.8 0.0035 17.5 1.4 5.3 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM03766.1 - 6.2e-05 22.7 2.3 6.2e-05 22.7 1.6 4.0 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.2 KFM03766.1 - 0.33 11.2 38.1 1.3 9.3 0.8 5.6 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 KFM03766.1 - 2.6 8.4 31.0 0.05 13.8 3.0 5.4 4 0 0 4 4 4 0 C2H2-type zinc-finger domain DUF3573 PF12097.3 KFM03766.1 - 7.1 5.1 9.2 11 4.5 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) Endothelin PF00322.12 KFM03767.1 - 2.1e-05 23.6 2.2 4.2e-05 22.6 1.5 1.4 1 0 0 1 1 1 1 Endothelin family RPEL PF02755.10 KFM03768.1 - 3.9e-37 124.5 26.5 4.7e-10 38.4 1.6 4.5 4 0 0 4 4 4 4 RPEL repeat RabGAP-TBC PF00566.13 KFM03770.1 - 6.7e-05 22.4 6.1 0.0014 18.1 3.4 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain GFO_IDH_MocA_C PF02894.12 KFM03772.1 - 0.0022 17.7 0.1 0.0068 16.1 0.1 1.8 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Tmemb_14 PF03647.8 KFM03773.1 - 4.4e-31 107.1 9.6 4.9e-31 106.9 6.6 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C PEMT PF04191.8 KFM03773.1 - 0.12 12.4 0.3 0.44 10.6 0.2 1.9 1 1 0 1 1 1 0 Phospholipid methyltransferase 7TM-7TMR_HD PF07698.6 KFM03773.1 - 0.31 10.4 3.1 0.37 10.2 2.1 1.2 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase CytB6-F_Fe-S PF08802.5 KFM03773.1 - 1.6 8.7 6.3 3.8 7.6 0.4 3.0 2 1 1 3 3 3 0 Cytochrome B6-F complex Fe-S subunit Gly-zipper_OmpA PF13436.1 KFM03773.1 - 3 7.5 4.7 1.6 8.4 1.9 1.5 1 1 1 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain WD40 PF00400.27 KFM03774.1 - 1.2e-28 97.8 10.0 6.1e-08 32.2 0.4 6.3 5 2 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 KFM03774.1 - 1.4e-05 23.4 1.2 0.0035 15.5 0.1 2.8 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 KFM03774.1 - 2.6e-05 24.0 0.3 0.23 11.1 0.1 2.7 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.1 KFM03774.1 - 0.00038 20.2 0.2 1 9.1 0.1 3.2 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region RNA_pol_Rpc4 PF05132.9 KFM03774.1 - 1.1 9.2 0.0 1.1 9.2 0.0 2.4 2 1 0 2 2 2 0 RNA polymerase III RPC4 RRM_1 PF00076.17 KFM03775.1 - 3.1e-11 42.7 0.0 4.9e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM03775.1 - 0.00022 21.1 0.0 0.00034 20.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM03775.1 - 0.077 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup153 PF08604.5 KFM03776.1 - 2.8e-186 620.2 41.4 2.8e-186 620.2 28.7 4.8 5 1 0 5 5 5 1 Nucleoporin Nup153-like zf-RanBP PF00641.13 KFM03776.1 - 2.3e-36 122.5 29.1 1.3e-11 43.4 1.4 4.4 4 0 0 4 4 4 4 Zn-finger in Ran binding protein and others Nup_retrotrp_bd PF10599.4 KFM03776.1 - 1.4e-12 48.1 16.4 1.4e-12 48.1 11.4 11.5 5 2 5 10 10 10 1 Retro-transposon transporting motif DZR PF12773.2 KFM03776.1 - 0.17 11.6 16.5 0.12 12.1 2.7 3.4 2 1 2 4 4 4 0 Double zinc ribbon FdhE PF04216.7 KFM03776.1 - 4.1 7.0 8.8 35 3.9 0.3 3.3 3 0 0 3 3 3 0 Protein involved in formate dehydrogenase formation RDD PF06271.7 KFM03777.1 - 3.4e-31 107.9 5.8 5e-31 107.4 4.0 1.2 1 0 0 1 1 1 1 RDD family DUF655 PF04919.7 KFM03777.1 - 0.14 11.8 0.3 0.19 11.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF655) AXH PF08517.7 KFM03778.1 - 1.2e-46 157.6 0.2 2.1e-46 156.7 0.1 1.4 1 0 0 1 1 1 1 Ataxin-1 and HBP1 module (AXH) ATXN-1_C PF12547.3 KFM03778.1 - 1.1e-21 76.5 2.2 1.1e-21 76.5 1.5 3.6 3 0 0 3 3 3 1 Capicua transcriptional repressor modulator Put_DNA-bind_N PF06971.8 KFM03778.1 - 0.041 13.6 0.2 0.088 12.5 0.1 1.5 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus IMPDH PF00478.20 KFM03779.1 - 1.4e-118 395.8 0.2 2e-118 395.2 0.2 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KFM03779.1 - 7.1e-05 21.8 1.1 0.00012 21.0 0.8 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase PcrB PF01884.12 KFM03779.1 - 0.026 13.7 2.8 0.12 11.6 0.0 2.4 3 0 0 3 3 3 0 PcrB family FERM_M PF00373.13 KFM03780.1 - 3.7e-18 65.9 2.5 1.5e-17 63.9 1.7 2.0 1 1 0 1 1 1 1 FERM central domain FERM_N PF09379.5 KFM03780.1 - 9.9e-13 47.9 0.0 2.7e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 FERM N-terminal domain zf-C3HC4_3 PF13920.1 KFM03780.1 - 5.4e-11 41.9 20.9 1.5e-10 40.5 14.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM03780.1 - 0.00041 20.3 24.5 0.00052 19.9 15.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FERM_C PF09380.5 KFM03780.1 - 0.00067 19.8 0.0 0.0018 18.4 0.0 1.8 1 0 0 1 1 1 1 FERM C-terminal PH-like domain Prok-RING_4 PF14447.1 KFM03780.1 - 0.02 14.4 12.6 0.047 13.2 8.7 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Rab_eff_C PF04698.7 KFM03780.1 - 0.64 8.0 5.9 0.053 11.6 0.3 1.7 2 0 0 2 2 2 0 Rab effector MyRIP/melanophilin C-terminus Dysbindin PF04440.11 KFM03781.1 - 4.1e-50 169.3 9.5 8.4e-50 168.3 6.6 1.5 1 0 0 1 1 1 1 Dysbindin (Dystrobrevin binding protein 1) NPV_P10 PF05531.7 KFM03781.1 - 0.067 13.4 0.6 4.4 7.6 0.1 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Exonuc_VII_L PF02601.10 KFM03781.1 - 1.9 7.6 6.0 2.6 7.1 2.2 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit JmjC PF02373.17 KFM03782.1 - 8.9e-32 109.7 0.5 4.2e-31 107.5 0.2 2.3 2 0 0 2 2 2 1 JmjC domain, hydroxylase ARID PF01388.16 KFM03782.1 - 1.2e-27 95.6 0.0 2.8e-27 94.3 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.12 KFM03782.1 - 5.4e-13 48.2 0.1 1.4e-12 46.9 0.1 1.7 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.11 KFM03782.1 - 2e-11 43.7 6.4 2e-11 43.7 4.4 2.1 2 0 0 2 2 2 1 C5HC2 zinc finger zf-RING_5 PF14634.1 KFM03783.1 - 0.00013 21.6 12.7 0.00013 21.6 8.8 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 KFM03783.1 - 0.00057 19.6 11.6 0.00057 19.6 8.0 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KFM03783.1 - 0.026 14.1 12.3 0.066 12.8 8.5 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Phtf-FEM1B_bdg PF12129.3 KFM03783.1 - 0.042 13.2 4.2 0.065 12.5 2.9 1.2 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor FYVE PF01363.16 KFM03783.1 - 0.27 11.1 9.1 0.68 9.8 6.3 1.7 1 0 0 1 1 1 0 FYVE zinc finger zf-RING_UBOX PF13445.1 KFM03783.1 - 6.9 6.4 15.6 0.099 12.3 5.6 1.9 2 0 0 2 2 2 0 RING-type zinc-finger DUF1640 PF07798.6 KFM03784.1 - 3.6e-66 222.5 15.3 1.7e-65 220.4 10.6 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) HALZ PF02183.13 KFM03784.1 - 0.0059 16.2 3.0 0.014 15.0 0.3 2.4 2 0 0 2 2 2 1 Homeobox associated leucine zipper DUF972 PF06156.8 KFM03784.1 - 1.1 9.5 9.6 0.28 11.5 2.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Cullin_Nedd8 PF10557.4 KFM03784.1 - 3.8 7.4 11.1 0.18 11.6 1.7 2.8 2 1 1 3 3 3 0 Cullin protein neddylation domain CLTH PF10607.4 KFM03785.1 - 3.8e-48 162.8 0.0 5.3e-48 162.3 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 KFM03785.1 - 4.6e-26 91.3 0.9 6.8e-26 90.7 0.1 1.7 2 0 0 2 2 2 1 SPRY domain LisH PF08513.6 KFM03785.1 - 3.5e-06 26.5 0.0 7.9e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 LisH SIR2 PF02146.12 KFM03786.1 - 3.5e-49 166.9 0.0 5.3e-49 166.3 0.0 1.3 1 0 0 1 1 1 1 Sir2 family PNTB PF02233.11 KFM03786.1 - 0.0012 17.7 0.1 0.0073 15.1 0.0 1.9 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit NHL PF01436.16 KFM03787.1 - 2.1e-25 87.3 5.7 6.8e-05 22.6 0.1 6.4 6 0 0 6 6 6 6 NHL repeat SGL PF08450.7 KFM03787.1 - 0.0056 16.0 0.1 0.065 12.5 0.0 2.7 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region PQQ_3 PF13570.1 KFM03787.1 - 0.52 10.6 2.8 1.4 9.3 0.3 2.8 3 0 0 3 3 3 0 PQQ-like domain TPMT PF05724.6 KFM03788.1 - 2.5e-69 233.0 0.0 2.8e-69 232.9 0.0 1.0 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Amino_oxidase PF01593.19 KFM03789.1 - 1.1e-92 311.4 0.0 3.2e-92 309.9 0.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase zf-CW PF07496.10 KFM03789.1 - 1.5e-12 47.0 2.1 4.7e-12 45.4 1.5 1.9 1 0 0 1 1 1 1 CW-type Zinc Finger NAD_binding_8 PF13450.1 KFM03789.1 - 8.1e-12 44.9 0.2 1.9e-11 43.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFM03789.1 - 2.8e-11 42.9 0.2 3.9e-07 29.3 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 KFM03789.1 - 5.4e-09 35.4 0.2 2.7e-08 33.2 0.1 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 KFM03789.1 - 2.1e-08 34.4 2.1 3.2e-05 24.0 0.7 2.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFM03789.1 - 9.5e-07 29.1 1.0 0.00012 22.4 0.2 3.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFM03789.1 - 2.1e-06 26.4 2.0 1.8e-05 23.4 0.6 2.6 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.19 KFM03789.1 - 2.6e-06 26.5 1.7 1e-05 24.6 1.2 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KFM03789.1 - 5.7e-06 26.3 1.1 3.4e-05 23.8 0.6 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KFM03789.1 - 6.9e-06 25.3 0.4 6.4e-05 22.1 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain SWIRM PF04433.12 KFM03789.1 - 1e-05 25.5 0.1 2.5e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain Lycopene_cycl PF05834.7 KFM03789.1 - 0.00011 21.3 0.3 0.00071 18.5 0.1 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein 2-Hacid_dh_C PF02826.14 KFM03789.1 - 0.00014 21.0 0.0 0.00046 19.3 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 KFM03789.1 - 0.00036 20.3 1.1 0.082 12.6 0.1 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_oxidored PF12831.2 KFM03789.1 - 0.00044 19.4 0.4 0.00074 18.7 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KFM03789.1 - 0.00072 18.5 0.7 0.0012 17.7 0.5 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A zf-RING_2 PF13639.1 KFM03789.1 - 0.0019 17.9 4.2 0.006 16.3 2.9 1.9 1 0 0 1 1 1 1 Ring finger domain Shikimate_DH PF01488.15 KFM03789.1 - 0.0051 16.9 0.1 0.011 15.8 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 KFM03789.1 - 0.0082 15.5 0.3 0.015 14.6 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain ThiF PF00899.16 KFM03789.1 - 0.018 14.8 0.2 0.035 13.9 0.2 1.4 1 0 0 1 1 1 0 ThiF family AlaDh_PNT_C PF01262.16 KFM03789.1 - 0.023 14.2 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 KFM03789.1 - 0.036 14.3 1.8 0.1 12.8 0.1 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding zf-C3HC4 PF00097.20 KFM03789.1 - 0.081 12.5 4.0 0.32 10.6 2.7 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CPSase_L_chain PF00289.17 KFM03789.1 - 0.15 12.1 0.2 0.4 10.7 0.1 1.7 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Malic_M PF03949.10 KFM03789.1 - 0.16 11.4 0.3 0.37 10.2 0.1 1.6 1 1 0 1 1 1 0 Malic enzyme, NAD binding domain DEK_C PF08766.6 KFM03790.1 - 2.2e-18 65.7 0.8 4.6e-18 64.7 0.5 1.6 1 0 0 1 1 1 1 DEK C terminal domain SAP PF02037.22 KFM03790.1 - 4.9e-06 25.9 1.4 1.5e-05 24.3 0.0 2.7 2 0 0 2 2 2 1 SAP domain MIP-T3 PF10243.4 KFM03790.1 - 0.29 9.5 51.9 0.032 12.7 19.6 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 eIF-3c_N PF05470.7 KFM03790.1 - 3.2 5.7 29.4 0.44 8.5 2.8 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus IBR PF01485.16 KFM03791.1 - 1.7e-18 66.2 20.9 1.4e-12 47.3 5.1 5.1 4 1 1 5 5 5 2 IBR domain zf-RING_2 PF13639.1 KFM03791.1 - 0.0015 18.2 13.7 0.0015 18.2 9.5 4.4 3 1 1 4 4 4 3 Ring finger domain GrpE PF01025.14 KFM03792.1 - 6.2e-47 159.2 4.2 7.5e-47 158.9 2.9 1.1 1 0 0 1 1 1 1 GrpE Laminin_I PF06008.9 KFM03792.1 - 0.0067 15.7 7.9 0.0086 15.4 5.5 1.1 1 0 0 1 1 1 1 Laminin Domain I Cpn60_TCP1 PF00118.19 KFM03792.1 - 0.027 13.0 2.0 0.034 12.7 1.4 1.1 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family Atg14 PF10186.4 KFM03792.1 - 0.042 12.7 4.7 0.053 12.4 3.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 LOH1CR12 PF10158.4 KFM03792.1 - 0.053 13.3 1.2 0.075 12.8 0.9 1.4 1 0 0 1 1 1 0 Tumour suppressor protein DUF1993 PF09351.5 KFM03792.1 - 0.11 12.4 3.2 3.4 7.5 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) LRAT PF04970.8 KFM03792.1 - 0.18 11.7 0.8 0.27 11.1 0.5 1.3 1 0 0 1 1 1 0 Lecithin retinol acyltransferase DUF2205 PF10224.4 KFM03792.1 - 0.29 10.7 6.9 0.25 10.9 3.5 1.8 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) Bac_GDH PF05088.7 KFM03792.1 - 0.4 8.0 3.7 0.47 7.7 2.6 1.0 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase DUF3391 PF11871.3 KFM03792.1 - 1.3 9.2 5.7 3.1 8.0 3.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) SWIRM PF04433.12 KFM03793.1 - 8.5e-05 22.6 0.3 0.00031 20.8 0.0 2.2 2 1 0 2 2 2 1 SWIRM domain Pertussis_S1 PF02917.9 KFM03793.1 - 0.047 13.2 0.0 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 Pertussis toxin, subunit 1 RabGAP-TBC PF00566.13 KFM03794.1 - 1.6e-47 161.7 0.0 3.3e-47 160.7 0.0 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF4603 PF15376.1 KFM03795.1 - 0 2613.6 50.4 0 2613.3 34.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4603) Transglut_i_TM PF14400.1 KFM03795.1 - 0.0032 17.0 0.0 0.009 15.5 0.0 1.7 1 0 0 1 1 1 1 Inactive transglutaminase fused to 7 transmembrane helices Glyco_hydro_38C PF07748.8 KFM03796.1 - 9.8e-81 271.8 4.1 1.3e-80 271.4 2.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Glyco_hydro_38 PF01074.17 KFM03796.1 - 9e-74 248.1 4.3 1.6e-73 247.3 3.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.6 KFM03796.1 - 1.8e-15 56.8 0.0 5.7e-15 55.2 0.0 2.0 1 0 0 1 1 1 1 Alpha mannosidase, middle domain WD40 PF00400.27 KFM03798.1 - 2.3e-11 43.1 5.9 0.67 9.9 0.1 7.5 7 1 0 7 7 7 4 WD domain, G-beta repeat Y_phosphatase2 PF03162.8 KFM03798.1 - 0.091 12.1 0.4 2.5 7.4 0.1 2.3 2 0 0 2 2 2 0 Tyrosine phosphatase family MLANA PF14991.1 KFM03799.1 - 0.13 12.2 0.3 0.4 10.7 0.2 1.8 1 0 0 1 1 1 0 Protein melan-A ADIP PF11559.3 KFM03800.1 - 0.0031 17.4 13.5 0.0031 17.4 9.3 8.7 5 4 5 10 10 10 4 Afadin- and alpha -actinin-Binding AHS1 PF02682.11 KFM03800.1 - 2.2 7.6 5.3 1 8.7 1.0 2.4 2 0 0 2 2 2 0 Allophanate hydrolase subunit 1 DUF2935 PF11155.3 KFM03801.1 - 0.11 12.6 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) Amidohydro_1 PF01979.15 KFM03802.1 - 1.1e-26 94.2 0.0 1.4e-26 93.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KFM03802.1 - 7.1e-13 49.2 0.0 1.1e-12 48.6 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KFM03802.1 - 2.7e-07 30.3 2.0 3.5e-07 29.9 0.1 2.2 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 KFM03802.1 - 0.00073 18.8 0.0 0.0012 18.1 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family EVC2_like PF12297.3 KFM03804.1 - 1.4e-172 574.1 27.3 1.4e-172 574.1 19.0 4.2 3 2 0 4 4 4 1 Ellis van Creveld protein 2 like protein Pkinase PF00069.20 KFM03805.1 - 8.8e-55 185.6 0.0 9.9e-55 185.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM03805.1 - 3.9e-32 111.3 0.0 5.3e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM03805.1 - 4e-11 42.4 0.0 4.8e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFM03805.1 - 0.0015 18.2 0.5 0.0023 17.6 0.3 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KFM03805.1 - 0.099 11.6 0.2 0.16 10.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CYTL1 PF15153.1 KFM03806.1 - 3.1e-55 185.4 2.4 3.9e-55 185.1 1.7 1.0 1 0 0 1 1 1 1 Cytokine-like protein 1 Homeobox PF00046.24 KFM03807.1 - 6.9e-20 70.4 5.2 1e-19 69.9 3.6 1.3 1 0 0 1 1 1 1 Homeobox domain TPX2 PF06886.6 KFM03807.1 - 0.77 9.8 5.9 0.18 11.8 0.3 2.1 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) Syntaxin-18_N PF10496.4 KFM03808.1 - 1.1e-09 37.9 0.3 3.4e-09 36.4 0.2 1.9 1 0 0 1 1 1 1 SNARE-complex protein Syntaxin-18 N-terminus TipAS PF07739.8 KFM03808.1 - 0.014 15.6 3.2 0.78 10.0 0.2 2.4 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain SNARE PF05739.14 KFM03808.1 - 0.024 14.3 3.6 0.059 13.0 2.5 1.7 1 0 0 1 1 1 0 SNARE domain HrpB4 PF09502.5 KFM03808.1 - 0.16 11.1 0.1 0.23 10.6 0.1 1.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB4) Calcyon PF06387.6 KFM03809.1 - 4.2e-95 316.4 0.1 4.6e-95 316.2 0.1 1.0 1 0 0 1 1 1 1 D1 dopamine receptor-interacting protein (calcyon) DUF2448 PF10476.4 KFM03809.1 - 0.014 14.8 0.1 0.031 13.7 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function C-terminus (DUF2448) MgsA_C PF12002.3 KFM03809.1 - 0.039 13.6 0.2 0.067 12.8 0.1 1.3 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal CPW_WPC PF09717.5 KFM03809.1 - 0.1 13.2 0.1 0.17 12.4 0.1 1.4 1 0 0 1 1 1 0 Plasmodium falciparum domain of unknown function (CPW_WPC) zf-H2C2_2 PF13465.1 KFM03810.1 - 9.3e-50 164.5 45.5 8.7e-09 35.2 3.0 8.6 8 0 0 8 8 8 7 Zinc-finger double domain zf-C2H2 PF00096.21 KFM03810.1 - 2.5e-36 121.8 51.9 3.3e-06 27.1 0.8 8.1 7 0 0 7 7 7 7 Zinc finger, C2H2 type BTB PF00651.26 KFM03810.1 - 6.5e-26 90.5 0.8 1.4e-25 89.4 0.6 1.6 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_4 PF13894.1 KFM03810.1 - 7.5e-23 79.1 44.7 0.00016 21.7 0.7 8.1 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM03810.1 - 2.1e-18 65.5 43.4 0.00023 20.9 0.3 7.9 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM03810.1 - 6.6e-18 64.3 33.2 0.00059 19.9 0.5 8.5 8 0 0 8 8 8 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM03810.1 - 2.4e-10 40.2 43.3 0.0047 17.0 0.5 9.0 9 0 0 9 9 9 5 Zinc-finger of C2H2 type GAGA PF09237.6 KFM03810.1 - 2.7e-05 23.6 14.6 0.13 11.8 0.1 5.5 2 2 4 6 6 6 3 GAGA factor BolA PF01722.13 KFM03810.1 - 0.25 11.3 3.5 20 5.2 0.1 4.3 3 2 0 3 3 3 0 BolA-like protein zf-C2HC_2 PF13913.1 KFM03810.1 - 0.73 9.5 31.7 0.69 9.6 0.3 7.1 7 0 0 7 7 7 0 zinc-finger of a C2HC-type Elf1 PF05129.8 KFM03810.1 - 2.8 7.7 24.2 0.52 10.0 2.8 4.4 2 2 2 4 4 4 0 Transcription elongation factor Elf1 like C1_2 PF03107.11 KFM03810.1 - 4.7 7.4 31.1 5.4 7.2 0.6 7.9 7 0 0 7 7 7 0 C1 domain zf-LYAR PF08790.6 KFM03811.1 - 5.6e-14 51.5 1.4 5.6e-14 51.5 1.0 2.3 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger RRN3 PF05327.6 KFM03811.1 - 0.0036 15.4 8.4 0.0051 14.9 5.8 1.3 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 IBR PF01485.16 KFM03811.1 - 0.54 10.1 11.8 1.4 8.8 8.2 1.7 1 0 0 1 1 1 0 IBR domain C1_4 PF07975.7 KFM03811.1 - 0.69 9.9 10.0 1.9 8.5 6.9 1.8 1 0 0 1 1 1 0 TFIIH C1-like domain YhfH PF14149.1 KFM03811.1 - 5.1 6.9 10.3 1.2 8.9 2.1 2.8 3 0 0 3 3 3 0 YhfH-like protein DUF2975 PF11188.3 KFM03812.1 - 7 6.3 9.5 4.4 7.0 2.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2975) Otopetrin PF03189.8 KFM03813.1 - 1.7e-39 136.0 17.5 1.5e-18 67.0 3.6 3.3 2 1 0 3 3 3 3 Otopetrin 7tm_1 PF00001.16 KFM03814.1 - 5e-84 281.4 14.8 6.6e-84 281.0 10.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM03814.1 - 8.2e-13 48.1 12.9 1.2e-11 44.2 9.0 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM03814.1 - 4e-06 26.1 11.1 4e-06 26.1 7.7 2.6 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx zf-LITAF-like PF10601.4 KFM03814.1 - 0.035 13.9 2.1 0.18 11.6 1.4 2.2 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain DUF3390 PF11870.3 KFM03814.1 - 0.18 11.7 0.6 8.5 6.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3390) Sugar_tr PF00083.19 KFM03815.1 - 2.6e-108 362.5 26.6 3e-108 362.3 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFM03815.1 - 2.6e-30 105.3 44.2 4.5e-24 84.8 14.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Hexokinase_2 PF03727.11 KFM03816.1 - 1.1e-193 640.4 6.3 1.3e-104 348.7 0.0 4.2 3 1 1 4 4 4 4 Hexokinase Hexokinase_1 PF00349.16 KFM03816.1 - 1.4e-178 589.5 1.1 2.3e-89 298.1 0.1 2.2 2 0 0 2 2 2 2 Hexokinase DUF1997 PF09366.5 KFM03816.1 - 0.053 13.2 0.0 4.1 7.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1997) FGGY_N PF00370.16 KFM03816.1 - 0.13 11.5 0.0 2.6 7.2 0.0 2.2 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, N-terminal domain DUF347 PF03988.7 KFM03816.1 - 1.3 8.9 4.3 5.8 6.8 0.1 2.9 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) BTB PF00651.26 KFM03817.1 - 1.5e-14 53.9 0.0 5.9e-14 51.9 0.0 2.0 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.10 KFM03817.1 - 5.9e-07 29.2 0.2 1.8e-06 27.7 0.1 1.9 1 0 0 1 1 1 1 BTB And C-terminal Kelch Annexin PF00191.15 KFM03818.1 - 1.8e-94 309.6 7.7 9.9e-25 86.2 0.0 4.0 4 0 0 4 4 4 4 Annexin DUF1678 PF07913.6 KFM03818.1 - 0.12 11.9 0.0 7.7 6.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1678) Pkinase PF00069.20 KFM03819.1 - 1.1e-42 146.0 0.0 1.1e-42 146.0 0.0 1.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM03819.1 - 6.4e-27 94.2 0.0 6.4e-27 94.2 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KFM03819.1 - 0.076 12.7 0.2 0.076 12.7 0.1 3.9 2 2 2 4 4 4 0 Phosphotransferase enzyme family BMP2K_C PF15282.1 KFM03821.1 - 4.3e-69 233.1 9.1 4.3e-69 233.1 6.3 2.3 2 1 0 2 2 2 2 BMP-2-inducible protein kinase C-terminus Nfu_N PF08712.6 KFM03822.1 - 6.1e-34 115.5 0.1 1.2e-33 114.5 0.0 1.6 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 KFM03822.1 - 2.1e-21 75.4 0.1 3e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 NifU-like domain SIS PF01380.17 KFM03823.1 - 3e-65 217.7 0.0 2.2e-34 117.8 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 KFM03823.1 - 3.4e-28 98.4 0.0 1.9e-20 72.9 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KFM03823.1 - 8.3e-18 64.6 0.0 2e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KFM03823.1 - 4.6e-14 52.2 0.0 1.1e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 KFM03823.1 - 1e-07 30.9 0.1 1.6e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 KFM03823.1 - 0.0022 17.6 0.0 0.0062 16.2 0.0 1.8 1 0 0 1 1 1 1 SIS domain Ant_C PF05586.6 KFM03824.1 - 2.2e-42 143.3 0.3 2.7e-42 143.1 0.2 1.1 1 0 0 1 1 1 1 Anthrax receptor C-terminus region BRICHOS PF04089.9 KFM03825.1 - 8e-19 67.3 0.0 9.3e-19 67.0 0.0 1.1 1 0 0 1 1 1 1 BRICHOS domain TGF_beta PF00019.15 KFM03826.1 - 1.1e-36 125.2 0.6 2.2e-36 124.3 0.4 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.13 KFM03826.1 - 4.3e-32 111.3 0.1 6.5e-32 110.7 0.1 1.2 1 0 0 1 1 1 1 TGF-beta propeptide RhoGAP PF00620.22 KFM03827.1 - 5.9e-44 149.3 1.9 4.4e-43 146.5 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.24 KFM03827.1 - 6.1e-11 42.4 0.7 3.7e-10 39.9 0.5 2.3 1 1 0 1 1 1 1 PH domain PH_11 PF15413.1 KFM03827.1 - 2.2e-07 31.1 1.6 4.3e-05 23.7 0.8 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 KFM03827.1 - 0.00019 21.4 0.4 0.0058 16.6 0.1 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.1 KFM03827.1 - 0.091 12.9 3.2 0.59 10.2 0.1 2.9 3 0 0 3 3 3 0 Pleckstrin homology domain Nsp1_C PF05064.8 KFM03827.1 - 0.3 10.7 11.7 1.9 8.1 8.3 2.1 2 0 0 2 2 2 0 Nsp1-like C-terminal region CTP_transf_1 PF01148.15 KFM03828.1 - 7.6e-90 301.0 26.1 9.3e-90 300.7 18.1 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family PCNA_C PF02747.10 KFM03829.1 - 2.1e-68 228.1 0.0 2.9e-68 227.6 0.0 1.2 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.13 KFM03829.1 - 4.1e-19 68.3 0.6 9.3e-19 67.1 0.4 1.6 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad1 PF02144.11 KFM03829.1 - 8.8e-05 21.4 0.1 0.00011 21.0 0.1 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 DUF872 PF05915.7 KFM03830.1 - 9.5e-28 96.3 0.9 1.2e-27 96.0 0.6 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) UbiA PF01040.13 KFM03830.1 - 0.013 14.7 0.9 0.015 14.5 0.6 1.1 1 0 0 1 1 1 0 UbiA prenyltransferase family DUF308 PF03729.8 KFM03830.1 - 0.033 14.1 11.0 0.05 13.5 6.9 1.7 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) Pox_A14 PF05767.7 KFM03830.1 - 0.07 13.1 0.9 0.13 12.2 0.0 1.8 1 1 1 2 2 2 0 Poxvirus virion envelope protein A14 DUF973 PF06157.6 KFM03830.1 - 0.23 10.4 4.9 0.3 10.0 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF1700 PF08006.6 KFM03830.1 - 0.23 10.7 2.9 0.3 10.3 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Neurensin PF14927.1 KFM03830.1 - 0.3 10.4 3.4 3.4 7.0 2.3 2.0 1 1 0 1 1 1 0 Neurensin RseC_MucC PF04246.7 KFM03830.1 - 0.92 9.0 4.3 1.2 8.6 3.0 1.1 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC SdpI PF13630.1 KFM03830.1 - 2.3 8.0 7.9 3.3 7.4 5.5 1.3 1 0 0 1 1 1 0 SdpI/YhfL protein family Tetraspannin PF00335.15 KFM03830.1 - 2.7 7.1 5.0 3.5 6.8 3.5 1.1 1 0 0 1 1 1 0 Tetraspanin family DUF2627 PF11118.3 KFM03830.1 - 5.2 7.2 7.8 1.1 9.4 2.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2627) Xan_ur_permease PF00860.15 KFM03831.1 - 1.5e-90 303.4 21.1 2.2e-90 302.9 14.6 1.2 1 0 0 1 1 1 1 Permease family RA PF00788.18 KFM03832.1 - 8.2e-12 45.4 0.0 1.6e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Ras_bdg_2 PF14847.1 KFM03832.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.7 1 1 0 1 1 1 0 Ras-binding domain of Byr2 Prominin PF05478.6 KFM03833.1 - 9.5e-132 440.2 0.0 1.2e-131 439.9 0.0 1.0 1 0 0 1 1 1 1 Prominin DSPc PF00782.15 KFM03834.1 - 1e-15 57.5 0.0 1.1e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DSPn PF14671.1 KFM03834.1 - 0.0021 18.0 0.0 0.0096 15.9 0.0 1.8 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half Y_phosphatase PF00102.22 KFM03834.1 - 0.0023 17.3 0.0 0.0023 17.3 0.0 1.2 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KFM03834.1 - 0.0052 17.0 0.0 0.0068 16.6 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family USP8_dimer PF08969.6 KFM03835.1 - 1.4e-19 70.1 0.3 1.4e-19 70.1 0.2 1.9 1 1 0 1 1 1 1 USP8 dimerisation domain JAB PF01398.16 KFM03835.1 - 4e-18 65.2 0.0 4e-18 65.2 0.0 2.3 2 1 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 KFM03835.1 - 5e-08 32.4 0.8 3.9e-07 29.5 0.0 2.2 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain MRP-S27 PF10037.4 KFM03835.1 - 3.5 6.4 11.9 4.9 5.9 8.2 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 DUF3959 PF13105.1 KFM03835.1 - 5.3 6.2 6.0 8.1 5.6 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) CRF PF00473.12 KFM03835.1 - 6.5 6.9 6.6 6.2 6.9 0.0 2.8 2 0 0 2 2 2 0 Corticotropin-releasing factor family Actin PF00022.14 KFM03836.1 - 7.3e-161 534.9 0.0 8.2e-161 534.8 0.0 1.0 1 0 0 1 1 1 1 Actin dNK PF01712.14 KFM03837.1 - 4.8e-27 94.6 0.0 5.3e-27 94.5 0.0 1.0 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.1 KFM03837.1 - 0.0015 18.8 0.1 0.014 15.7 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 KFM03837.1 - 0.016 15.0 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain KH_1 PF00013.24 KFM03838.1 - 2.8e-19 68.5 2.1 1.4e-13 50.2 0.1 2.3 2 0 0 2 2 2 2 KH domain zf-C3HC4_3 PF13920.1 KFM03838.1 - 3.5e-11 42.6 11.7 5.1e-11 42.0 8.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) KH_3 PF13014.1 KFM03838.1 - 5e-10 38.7 0.1 1e-06 28.2 0.0 2.9 2 0 0 2 2 2 2 KH domain zf-C3HC4_2 PF13923.1 KFM03838.1 - 7.4e-08 32.2 13.3 1.2e-07 31.6 9.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM03838.1 - 4.8e-05 22.9 13.1 7.8e-05 22.2 9.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM03838.1 - 0.00011 21.9 12.2 0.00018 21.2 8.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KFM03838.1 - 0.0033 17.1 11.3 0.0056 16.3 7.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain KH_2 PF07650.12 KFM03838.1 - 0.044 13.3 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 KH domain zf-C2HC5 PF06221.8 KFM03838.1 - 0.096 12.4 7.1 0.21 11.3 4.9 1.5 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type zf-C3HC4_4 PF15227.1 KFM03838.1 - 0.4 10.5 11.7 0.92 9.4 8.2 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KFM03838.1 - 0.61 9.7 8.5 1.2 8.7 5.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain MH2 PF03166.9 KFM03839.1 - 3.6e-77 258.3 0.0 5e-77 257.8 0.0 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.11 KFM03839.1 - 3.4e-40 136.2 0.5 7.6e-40 135.0 0.3 1.6 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.4 KFM03839.1 - 0.00054 19.5 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 Interferon-regulatory factor 3 Lactamase_B PF00753.22 KFM03840.1 - 2.4e-13 50.1 0.0 4.2e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KFM03840.1 - 1.4e-11 44.2 0.0 2e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 KFM03840.1 - 5.3e-06 25.8 0.0 1e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 tRNase Z endonuclease GVQW PF13900.1 KFM03840.1 - 0.27 11.2 1.4 3 7.8 0.0 2.4 2 0 0 2 2 2 0 Putative binding domain Malic_M PF03949.10 KFM03841.1 - 3.2e-88 295.5 0.1 4.1e-88 295.2 0.1 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KFM03841.1 - 9.5e-80 266.4 0.0 1.6e-79 265.7 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Pol_alpha_B_N PF08418.5 KFM03841.1 - 0.11 12.0 0.1 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Pkinase PF00069.20 KFM03842.1 - 6e-69 232.0 0.0 7.7e-69 231.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM03842.1 - 2.6e-31 108.6 0.0 3.6e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFM03842.1 - 0.0031 16.6 0.1 0.0056 15.7 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFM03842.1 - 0.072 12.8 0.0 0.22 11.2 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KFM03842.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF1395 PF07160.7 KFM03843.1 - 6.9e-72 241.8 10.2 8.1e-72 241.6 7.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1395) SlyX PF04102.7 KFM03843.1 - 0.049 13.9 6.6 0.17 12.2 2.8 2.7 2 0 0 2 2 2 0 SlyX DUF3161 PF11362.3 KFM03843.1 - 0.087 12.7 0.1 0.39 10.6 0.0 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3161) GAT PF03127.9 KFM03843.1 - 0.1 12.5 3.7 0.094 12.6 1.2 1.9 2 0 0 2 2 2 0 GAT domain RGS PF00615.14 KFM03843.1 - 0.13 12.3 3.2 0.98 9.5 0.1 2.5 2 0 0 2 2 2 0 Regulator of G protein signaling domain DASH_Dad3 PF08656.5 KFM03843.1 - 1.3 8.7 6.7 3 7.6 0.0 2.8 2 1 0 2 2 2 0 DASH complex subunit Dad3 Trichoplein PF13868.1 KFM03844.1 - 8e-19 67.2 137.4 8e-19 67.2 95.2 2.3 1 1 1 2 2 2 1 Tumour suppressor, Mitostatin Myosin_head PF00063.16 KFM03845.1 - 6.3e-260 864.0 9.3 7.4e-260 863.7 6.5 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.22 KFM03845.1 - 4.8e-12 44.3 29.4 0.00074 18.9 1.0 4.7 4 0 0 4 4 4 4 IQ calmodulin-binding motif AAA_22 PF13401.1 KFM03845.1 - 0.0012 18.9 1.3 0.0083 16.2 0.0 2.9 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KFM03845.1 - 0.041 13.8 0.2 0.34 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Myosin_N PF02736.14 KFM03845.1 - 0.042 13.5 0.2 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain T2SE PF00437.15 KFM03845.1 - 0.05 12.4 0.0 0.14 10.9 0.0 1.8 1 0 0 1 1 1 0 Type II/IV secretion system protein Nop10p PF04135.7 KFM03845.1 - 0.077 12.7 0.4 0.2 11.4 0.2 1.6 1 0 0 1 1 1 0 Nucleolar RNA-binding protein, Nop10p family AAA_10 PF12846.2 KFM03845.1 - 0.097 12.0 0.7 0.39 10.1 0.1 2.1 2 0 0 2 2 2 0 AAA-like domain AAA_19 PF13245.1 KFM03845.1 - 0.21 11.3 0.9 0.37 10.5 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain DUF218 PF02698.12 KFM03845.1 - 1.7 8.0 4.8 25 4.3 0.0 2.4 2 0 0 2 2 2 0 DUF218 domain DUF2353 PF09789.4 KFM03846.1 - 0.0044 16.3 19.1 0.0054 16.0 13.2 1.0 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) DUF342 PF03961.8 KFM03846.1 - 0.0051 15.2 13.0 0.0056 15.1 9.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF342) Sipho_Gp157 PF05565.6 KFM03846.1 - 0.008 15.7 10.4 0.011 15.3 7.2 1.3 1 0 0 1 1 1 1 Siphovirus Gp157 EzrA PF06160.7 KFM03846.1 - 0.012 13.8 14.7 0.017 13.3 10.2 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA APG6 PF04111.7 KFM03846.1 - 0.036 13.1 22.0 0.046 12.7 15.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 KFM03846.1 - 0.1 12.4 25.7 0.15 11.9 17.8 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.3 KFM03846.1 - 0.11 12.2 23.6 0.23 11.1 7.5 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Acetate_kinase PF00871.12 KFM03846.1 - 0.12 10.9 1.1 0.21 10.1 0.1 1.6 1 1 1 2 2 2 0 Acetokinase family bZIP_1 PF00170.16 KFM03846.1 - 0.12 12.3 17.4 0.43 10.5 4.9 2.6 2 0 0 2 2 2 0 bZIP transcription factor Sec7 PF01369.15 KFM03846.1 - 0.17 11.5 3.7 0.21 11.2 2.6 1.4 1 0 0 1 1 1 0 Sec7 domain DUF2492 PF10678.4 KFM03846.1 - 0.19 11.7 2.1 0.34 11.0 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2492) GAS PF13851.1 KFM03846.1 - 0.43 9.7 26.6 0.073 12.2 9.0 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding AAA_13 PF13166.1 KFM03846.1 - 0.45 8.8 11.7 0.57 8.5 8.1 1.1 1 0 0 1 1 1 0 AAA domain TPD52 PF04201.10 KFM03846.1 - 0.5 10.0 9.4 0.68 9.6 6.5 1.4 1 0 0 1 1 1 0 Tumour protein D52 family Uso1_p115_C PF04871.8 KFM03846.1 - 0.58 10.0 16.7 0.81 9.6 11.6 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region AAA_32 PF13654.1 KFM03846.1 - 0.67 8.5 15.1 0.84 8.2 10.4 1.0 1 0 0 1 1 1 0 AAA domain IZUMO PF15005.1 KFM03846.1 - 0.67 9.9 11.6 0.14 12.2 5.9 1.4 2 0 0 2 2 1 0 Izumo sperm-egg fusion MRP-S27 PF10037.4 KFM03846.1 - 0.77 8.6 15.2 0.91 8.3 10.5 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Lectin_N PF03954.9 KFM03846.1 - 0.8 9.0 5.4 2.2 7.6 3.8 1.8 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain RdRP_4 PF02123.11 KFM03846.1 - 0.9 8.1 6.0 1.1 7.9 4.1 1.0 1 0 0 1 1 1 0 Viral RNA-directed RNA-polymerase V_ATPase_I PF01496.14 KFM03846.1 - 0.93 7.2 14.0 1.2 6.9 9.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SEO_N PF14576.1 KFM03846.1 - 1 8.5 8.3 0.14 11.3 2.2 1.9 1 1 1 2 2 2 0 Sieve element occlusion N-terminus NPV_P10 PF05531.7 KFM03846.1 - 1.2 9.4 9.7 2.8 8.2 1.5 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein ApoO PF09769.4 KFM03846.1 - 1.8 8.2 4.2 0.84 9.3 0.5 1.9 1 1 1 2 2 2 0 Apolipoprotein O FlaC_arch PF05377.6 KFM03846.1 - 2.2 8.2 11.1 4 7.3 0.8 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Ax_dynein_light PF10211.4 KFM03846.1 - 2.3 8.0 23.8 4.8 6.9 6.5 2.3 1 1 1 2 2 2 0 Axonemal dynein light chain IncA PF04156.9 KFM03846.1 - 2.8 7.4 25.3 3.2e+02 0.7 17.5 2.1 1 1 0 1 1 1 0 IncA protein Striatin PF08232.7 KFM03846.1 - 3 8.1 21.0 1.9 8.7 6.1 2.1 1 1 1 2 2 2 0 Striatin family ERp29 PF07749.7 KFM03846.1 - 3.5 8.3 12.8 2.4 8.8 0.9 2.2 1 1 1 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain Histidinol_dh PF00815.15 KFM03846.1 - 3.5 6.1 5.1 4.4 5.8 3.5 1.2 1 0 0 1 1 1 0 Histidinol dehydrogenase DUF2383 PF09537.5 KFM03846.1 - 3.6 7.8 10.9 2.1 8.6 1.5 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF2383) TMF_DNA_bd PF12329.3 KFM03846.1 - 3.6 7.4 24.2 4.6 7.1 3.0 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF2508 PF10704.4 KFM03846.1 - 4.1 7.6 14.8 0.26 11.4 2.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2508) Speriolin_N PF15058.1 KFM03846.1 - 4.8 7.0 11.0 2.1 8.1 2.2 2.2 1 1 1 2 2 2 0 Speriolin N terminus Prefoldin PF02996.12 KFM03846.1 - 4.9 6.8 18.1 1 9.0 2.9 2.5 2 1 0 2 2 2 0 Prefoldin subunit Vir_act_alpha_C PF10400.4 KFM03846.1 - 4.9 7.5 14.8 6.1 7.2 0.5 2.7 1 1 2 3 3 3 0 Virulence activator alpha C-term Dna2 PF08696.6 KFM03846.1 - 6.5 6.0 7.5 1.4 8.1 1.5 1.9 1 1 1 2 2 2 0 DNA replication factor Dna2 DUF4473 PF14747.1 KFM03846.1 - 6.5 7.0 8.9 13 6.0 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) CENP-H PF05837.7 KFM03846.1 - 7.1 6.8 15.8 1.2 9.2 4.2 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Prefoldin_2 PF01920.15 KFM03846.1 - 7.6 6.3 24.7 1.8 8.3 4.9 2.6 2 1 0 2 2 2 0 Prefoldin subunit DUF2664 PF10867.3 KFM03846.1 - 7.7 7.2 12.3 1.1 9.9 2.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2664) MotA_ExbB PF01618.11 KFM03846.1 - 8.2 6.0 6.9 2.6 7.6 0.3 2.3 2 1 0 2 2 2 0 MotA/TolQ/ExbB proton channel family DUF4407 PF14362.1 KFM03846.1 - 8.9 5.1 14.5 21 3.9 10.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Mnd1 PF03962.10 KFM03846.1 - 9.4 5.8 21.0 12 5.5 5.8 2.0 1 1 1 2 2 2 0 Mnd1 family Thiolase_N PF00108.18 KFM03847.1 - 1.7e-91 305.8 0.3 2.6e-91 305.2 0.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KFM03847.1 - 6e-53 177.4 0.3 1.3e-52 176.3 0.2 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KFM03847.1 - 0.001 18.6 0.8 0.017 14.5 0.4 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Lipase PF00151.14 KFM03848.1 - 3e-89 299.5 0.0 5e-89 298.7 0.0 1.3 1 0 0 1 1 1 1 Lipase PLAT PF01477.18 KFM03848.1 - 2.1e-19 69.9 0.7 5.5e-19 68.6 0.1 2.0 2 0 0 2 2 2 1 PLAT/LH2 domain Abhydrolase_6 PF12697.2 KFM03848.1 - 1.9e-07 31.2 0.3 3.4e-07 30.3 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFM03848.1 - 0.0021 17.8 0.0 0.0029 17.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 KFM03848.1 - 0.012 14.9 0.1 0.021 14.1 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) VirJ PF06057.6 KFM03848.1 - 0.025 14.3 0.0 0.056 13.2 0.0 1.6 1 1 0 1 1 1 0 Bacterial virulence protein (VirJ) Bac_export_2 PF01312.14 KFM03848.1 - 0.21 10.4 0.0 0.31 9.8 0.0 1.2 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Ribosomal_L22 PF00237.14 KFM03849.1 - 4e-38 129.5 0.1 6.3e-38 128.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF4512 PF14975.1 KFM03850.1 - 4e-19 69.2 0.7 4.5e-19 69.0 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4512) Dymeclin PF09742.4 KFM03851.1 - 8.4e-190 632.2 12.6 1.3e-189 631.6 8.7 1.3 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.2 KFM03851.1 - 1.1e-07 30.0 14.5 1.1e-07 30.0 10.0 1.6 2 0 0 2 2 2 1 High-temperature-induced dauer-formation protein Peptidase_C2 PF00648.16 KFM03852.1 - 1e-143 477.7 0.0 1.5e-143 477.1 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 KFM03852.1 - 9.7e-57 190.7 0.0 5.1e-56 188.4 0.0 2.0 2 0 0 2 2 2 1 Calpain large subunit, domain III EF-hand_1 PF00036.27 KFM03852.1 - 1.7e-12 45.6 0.6 0.00084 18.4 0.0 4.6 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 KFM03852.1 - 8e-12 43.9 0.1 0.019 14.7 0.0 4.8 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 KFM03852.1 - 1.3e-07 31.1 5.9 4.5e-06 26.1 0.1 4.1 4 1 0 4 4 4 1 EF-hand domain pair EF-hand_7 PF13499.1 KFM03852.1 - 1e-06 28.7 1.4 0.0073 16.4 0.1 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KFM03852.1 - 0.0002 20.5 0.1 5.8 6.4 0.0 3.7 3 0 0 3 3 3 2 EF hand Ank PF00023.25 KFM03853.1 - 3e-20 70.9 0.1 1.2e-08 34.3 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KFM03853.1 - 6.9e-18 64.7 0.0 1.5e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFM03853.1 - 1.4e-16 60.5 0.0 1e-11 45.0 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM03853.1 - 4.3e-14 51.2 0.1 1.2e-06 28.1 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 KFM03853.1 - 6.8e-13 48.3 1.2 7.3e-10 38.7 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) SH3_1 PF00018.23 KFM03853.1 - 1.9e-12 46.3 1.8 3.4e-12 45.5 1.2 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFM03853.1 - 3e-11 42.7 0.4 6.9e-11 41.5 0.3 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFM03853.1 - 1.5e-07 30.7 0.0 2.7e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain RA PF00788.18 KFM03853.1 - 0.0013 19.2 0.8 0.037 14.5 0.6 2.6 1 1 0 1 1 1 1 Ras association (RalGDS/AF-6) domain ATG16 PF08614.6 KFM03854.1 - 0.00085 19.1 3.3 0.00085 19.1 2.3 1.6 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) IncA PF04156.9 KFM03854.1 - 0.0045 16.6 8.5 0.0045 16.6 5.9 2.0 2 1 0 2 2 2 1 IncA protein Spc7 PF08317.6 KFM03854.1 - 0.0092 14.6 8.0 0.018 13.7 5.6 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein Filament PF00038.16 KFM03854.1 - 0.012 15.0 8.4 0.026 14.0 5.8 1.4 1 0 0 1 1 1 0 Intermediate filament protein DUF342 PF03961.8 KFM03854.1 - 0.016 13.6 1.1 0.024 13.0 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) SlyX PF04102.7 KFM03854.1 - 0.031 14.6 9.5 0.031 14.6 6.6 2.9 2 1 1 3 3 3 0 SlyX TPR_MLP1_2 PF07926.7 KFM03854.1 - 0.046 13.4 10.1 0.099 12.3 7.0 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 KFM03854.1 - 0.25 10.4 1.0 0.71 8.9 0.6 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein TBPIP PF07106.8 KFM03854.1 - 0.28 10.7 9.5 0.83 9.1 5.5 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Bacillus_HBL PF05791.6 KFM03854.1 - 0.29 10.4 6.9 0.58 9.4 4.8 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF3584 PF12128.3 KFM03854.1 - 0.36 8.0 11.1 0.054 10.8 5.2 1.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF2730 PF10805.3 KFM03854.1 - 0.4 10.4 6.3 0.77 9.5 2.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) DUF3450 PF11932.3 KFM03854.1 - 0.42 9.8 10.2 0.19 10.9 5.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Scaffolding_pro PF11418.3 KFM03854.1 - 0.64 10.3 5.2 0.62 10.4 2.4 1.8 2 0 0 2 2 2 0 Phi29 scaffolding protein Adeno_PIX PF03955.9 KFM03854.1 - 0.76 10.3 3.5 0.67 10.4 1.0 2.1 2 1 0 2 2 1 0 Adenovirus hexon-associated protein (IX) TMF_DNA_bd PF12329.3 KFM03854.1 - 1.5 8.6 15.8 3.7 7.4 0.6 2.6 2 1 1 3 3 2 0 TATA element modulatory factor 1 DNA binding DUF972 PF06156.8 KFM03854.1 - 1.7 9.0 10.8 1.3 9.4 4.2 2.6 2 1 1 3 3 2 0 Protein of unknown function (DUF972) TMF_TATA_bd PF12325.3 KFM03854.1 - 2.1 8.1 16.0 5.7 6.6 8.4 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding APG6 PF04111.7 KFM03854.1 - 2.6 7.0 8.5 4.4 6.2 5.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 COG2 PF06148.6 KFM03854.1 - 2.9 7.7 8.2 4.7 7.0 2.7 2.7 2 2 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 NPV_P10 PF05531.7 KFM03854.1 - 2.9 8.1 10.2 1.3 9.2 2.5 2.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Pox_A_type_inc PF04508.7 KFM03854.1 - 3 7.8 5.7 10 6.2 0.1 3.5 4 0 0 4 4 2 0 Viral A-type inclusion protein repeat DUF904 PF06005.7 KFM03854.1 - 3.7 7.9 14.3 15 6.0 9.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF3287 PF11690.3 KFM03854.1 - 5.2 7.1 8.5 1.2 9.2 2.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3287) DUF2458 PF10454.4 KFM03854.1 - 8.1 6.3 12.1 3.9 7.3 5.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2458) FA_desaturase PF00487.19 KFM03855.1 - 1e-23 84.1 13.0 1e-23 84.1 9.0 1.6 2 0 0 2 2 2 1 Fatty acid desaturase Lipid_DES PF08557.5 KFM03855.1 - 0.00097 18.3 0.1 0.0019 17.3 0.1 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) AAA PF00004.24 KFM03856.1 - 2.4e-93 309.2 0.0 2.2e-48 163.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KFM03856.1 - 1.6e-13 50.2 0.0 5.1e-06 25.7 0.0 2.9 2 1 1 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KFM03856.1 - 5e-13 49.3 1.2 0.00046 20.3 0.0 5.2 3 3 0 3 3 3 2 AAA domain AAA_16 PF13191.1 KFM03856.1 - 1.6e-12 47.7 5.2 5.2e-06 26.5 0.0 4.3 2 2 1 4 4 4 2 AAA ATPase domain AAA_2 PF07724.9 KFM03856.1 - 2.7e-12 46.9 0.0 4.8e-05 23.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 KFM03856.1 - 1.1e-10 42.3 0.0 0.0013 19.5 0.0 3.4 3 1 0 3 3 2 2 AAA domain AAA_5 PF07728.9 KFM03856.1 - 1.3e-10 41.1 1.6 5.4e-05 22.9 0.1 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KFM03856.1 - 5.4e-10 39.2 0.0 0.0011 18.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KFM03856.1 - 7e-09 35.0 0.1 0.00012 21.2 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_33 PF13671.1 KFM03856.1 - 1.4e-08 34.7 0.0 0.0027 17.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 KFM03856.1 - 1.5e-08 33.8 0.0 0.0033 16.1 0.0 2.6 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 KFM03856.1 - 2.7e-08 33.4 2.0 0.0077 15.9 0.3 3.1 2 1 0 2 2 2 2 Part of AAA domain Mg_chelatase PF01078.16 KFM03856.1 - 7.4e-08 31.7 0.2 0.0044 16.2 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 KFM03856.1 - 1.5e-07 31.0 5.9 0.067 12.5 0.0 4.4 2 2 2 4 4 4 2 AAA domain IstB_IS21 PF01695.12 KFM03856.1 - 4e-07 29.6 0.1 0.034 13.5 0.1 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.1 KFM03856.1 - 7.1e-07 29.3 0.0 0.061 13.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 KFM03856.1 - 8.4e-07 29.1 0.0 0.045 13.9 0.0 3.0 2 1 0 2 2 2 2 RNA helicase NACHT PF05729.7 KFM03856.1 - 1.1e-06 28.4 0.7 0.039 13.6 0.0 3.7 3 1 1 4 4 4 2 NACHT domain AAA_18 PF13238.1 KFM03856.1 - 1.3e-06 28.6 0.1 0.081 13.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 KFM03856.1 - 1.9e-06 27.6 0.0 0.052 13.0 0.0 2.6 3 0 0 3 3 2 2 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.6 KFM03856.1 - 1.4e-05 24.7 0.0 0.09 12.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 KFM03856.1 - 1.6e-05 25.2 0.0 0.23 11.7 0.0 3.3 3 1 0 3 3 2 2 ABC transporter KaiC PF06745.8 KFM03856.1 - 2.1e-05 23.7 0.9 0.56 9.2 0.0 3.7 2 1 0 3 3 3 1 KaiC Sigma54_activ_2 PF14532.1 KFM03856.1 - 2.5e-05 24.3 0.1 0.1 12.6 0.0 2.9 3 0 0 3 3 2 2 Sigma-54 interaction domain Cytidylate_kin2 PF13189.1 KFM03856.1 - 0.00019 21.3 0.0 0.31 10.9 0.0 2.5 2 0 0 2 2 2 2 Cytidylate kinase-like family Sigma54_activat PF00158.21 KFM03856.1 - 0.00021 20.8 0.0 0.34 10.3 0.0 3.3 2 1 1 3 3 3 1 Sigma-54 interaction domain NB-ARC PF00931.17 KFM03856.1 - 0.00028 19.8 0.0 0.46 9.2 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain DUF2075 PF09848.4 KFM03856.1 - 0.00031 19.8 0.1 1.1 8.2 0.0 3.6 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 KFM03856.1 - 0.0005 19.3 0.1 0.79 8.9 0.0 2.8 3 0 0 3 3 3 2 PhoH-like protein SKI PF01202.17 KFM03856.1 - 0.00093 19.0 0.0 0.46 10.3 0.0 3.0 3 0 0 3 3 2 1 Shikimate kinase Rad17 PF03215.10 KFM03856.1 - 0.0013 17.5 0.0 0.33 9.5 0.0 2.4 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein UPF0079 PF02367.12 KFM03856.1 - 0.0031 17.1 0.1 1.3 8.7 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 ATP-synt_ab PF00006.20 KFM03856.1 - 0.0032 17.0 0.0 1.4 8.3 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Arch_ATPase PF01637.13 KFM03856.1 - 0.0033 17.1 0.0 7.4 6.1 0.0 3.7 2 2 2 4 4 4 0 Archaeal ATPase NTPase_1 PF03266.10 KFM03856.1 - 0.0035 17.0 0.2 4.2 7.0 0.0 3.4 2 2 1 3 3 3 0 NTPase PduV-EutP PF10662.4 KFM03856.1 - 0.0051 16.3 0.0 2.2 7.7 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_11 PF13086.1 KFM03856.1 - 0.0051 16.4 0.1 1.4 8.4 0.0 2.9 3 0 0 3 3 3 1 AAA domain Parvo_NS1 PF01057.12 KFM03856.1 - 0.0052 15.7 0.0 1.8 7.3 0.0 2.6 3 0 0 3 3 3 1 Parvovirus non-structural protein NS1 DUF815 PF05673.8 KFM03856.1 - 0.0061 15.5 0.0 0.4 9.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_24 PF13479.1 KFM03856.1 - 0.023 14.2 0.0 2.9 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.4 KFM03856.1 - 0.06 12.2 0.1 3.9 6.3 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 Cornichon PF03311.9 KFM03857.1 - 5e-41 139.8 1.8 5.6e-41 139.6 1.3 1.0 1 0 0 1 1 1 1 Cornichon protein DUF1035 PF06281.7 KFM03857.1 - 0.095 12.5 0.1 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1035) DUF2650 PF10853.3 KFM03857.1 - 0.12 11.8 0.5 0.12 11.8 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2650) Lamp PF01299.12 KFM03857.1 - 0.14 11.2 0.1 0.18 10.8 0.1 1.1 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) WD40 PF00400.27 KFM03858.1 - 6.3e-43 143.1 3.5 8.9e-13 47.5 0.0 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 KFM03858.1 - 2.1e-05 24.3 0.0 0.00033 20.4 0.0 2.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A CLTH PF10607.4 KFM03858.1 - 0.093 12.4 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain ERG4_ERG24 PF01222.12 KFM03859.1 - 1.4e-185 616.9 11.9 1.7e-185 616.6 8.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family LBR_tudor PF09465.5 KFM03859.1 - 2.3e-33 113.6 0.3 4.5e-33 112.6 0.2 1.5 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain DUF1295 PF06966.7 KFM03859.1 - 1.2e-06 27.9 0.4 3.4e-06 26.5 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.8 KFM03859.1 - 2.9e-05 24.1 0.9 0.0001 22.3 0.1 2.4 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 KFM03859.1 - 0.0029 17.7 0.3 0.0029 17.7 0.2 2.4 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF4544 PF15077.1 KFM03859.1 - 0.044 13.2 0.2 0.096 12.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) DUF1325 PF07039.6 KFM03859.1 - 0.098 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 SGF29 tudor-like domain DUF1509 PF07420.6 KFM03859.1 - 0.84 8.8 8.2 1.2 8.3 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) DDHD PF02862.12 KFM03859.1 - 1.2 8.9 6.5 2.4 7.9 4.5 1.4 1 0 0 1 1 1 0 DDHD domain WH1 PF00568.18 KFM03860.1 - 5.8e-40 135.4 0.2 8.3e-40 134.9 0.1 1.2 1 0 0 1 1 1 1 WH1 domain VASP_tetra PF08776.6 KFM03860.1 - 2.8e-15 55.3 2.0 2.8e-15 55.3 1.4 2.7 2 0 0 2 2 2 1 VASP tetramerisation domain Exonuc_VII_L PF02601.10 KFM03860.1 - 0.00054 19.2 0.7 0.00064 19.0 0.0 1.5 2 0 0 2 2 2 1 Exonuclease VII, large subunit CAF-1_p150 PF11600.3 KFM03860.1 - 0.0074 15.6 45.8 0.0074 15.6 31.8 2.2 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal SRP9-21 PF05486.7 KFM03861.1 - 3.3e-12 45.9 0.1 3.7e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) DUF3128 PF11326.3 KFM03861.1 - 0.036 14.1 0.1 0.043 13.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3128) XhlA PF10779.4 KFM03861.1 - 0.16 11.8 0.4 0.19 11.6 0.3 1.1 1 0 0 1 1 1 0 Haemolysin XhlA Patched PF02460.13 KFM03862.1 - 1.3e-97 327.6 14.2 1.9e-97 327.1 9.8 1.1 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 KFM03862.1 - 4e-25 88.0 3.5 4e-25 88.0 2.4 3.0 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation FAM176 PF14851.1 KFM03865.1 - 4.1e-64 214.8 0.1 4.7e-64 214.6 0.1 1.0 1 0 0 1 1 1 1 FAM176 family Myc_target_1 PF15179.1 KFM03865.1 - 0.059 12.9 0.1 0.076 12.5 0.0 1.1 1 0 0 1 1 1 0 Myc target protein 1 PDGLE PF13190.1 KFM03865.1 - 0.07 12.8 0.1 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 PDGLE domain DUF755 PF05501.6 KFM03865.1 - 1.5 8.8 7.5 2.2 8.3 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Ribosomal_L19 PF01245.15 KFM03866.1 - 5.5e-18 64.8 0.0 9.2e-18 64.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 GCFC PF07842.7 KFM03867.1 - 2.7e-28 99.1 6.0 1.2e-27 96.9 4.1 2.0 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein NTR2 PF15458.1 KFM03867.1 - 0.00057 19.1 13.1 0.00089 18.5 3.4 3.1 3 0 0 3 3 3 2 Nineteen complex-related protein 2 Flu_NS1 PF00600.14 KFM03868.1 - 0.047 12.8 0.1 0.067 12.3 0.1 1.1 1 0 0 1 1 1 0 Influenza non-structural protein (NS1) SH3_9 PF14604.1 KFM03869.1 - 1.4e-68 226.2 6.4 3.1e-16 58.6 0.0 5.5 5 0 0 5 5 5 5 Variant SH3 domain SH3_1 PF00018.23 KFM03869.1 - 3.7e-66 218.3 8.9 4.9e-16 57.8 0.1 5.5 5 0 0 5 5 5 5 SH3 domain SH3_2 PF07653.12 KFM03869.1 - 6.6e-60 198.4 0.7 2.2e-13 49.4 0.0 5.5 5 0 0 5 5 5 5 Variant SH3 domain RhoGEF PF00621.15 KFM03869.1 - 4.5e-44 150.4 0.2 4.5e-44 150.4 0.1 3.5 2 1 0 2 2 1 1 RhoGEF domain EF-hand_4 PF12763.2 KFM03869.1 - 1e-29 102.3 0.0 1.7e-13 50.1 0.0 2.9 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand C2 PF00168.25 KFM03869.1 - 7.2e-21 73.8 0.0 1.8e-20 72.5 0.0 1.8 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.1 KFM03869.1 - 1.1e-09 38.2 0.0 3.2e-05 23.9 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KFM03869.1 - 1.8e-09 36.1 0.3 0.0046 16.1 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 KFM03869.1 - 1.4e-06 27.7 0.4 2.2 8.3 0.0 4.1 3 0 0 3 3 3 3 EF-hand domain PH PF00169.24 KFM03869.1 - 0.00018 21.6 2.5 0.00026 21.1 0.1 2.6 2 0 0 2 2 2 1 PH domain EF-hand_8 PF13833.1 KFM03869.1 - 0.0022 17.5 0.0 0.16 11.5 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 KFM03869.1 - 0.04 13.2 1.1 7.2 6.1 0.1 3.1 3 0 0 3 3 3 0 EF hand DUF3104 PF11302.3 KFM03869.1 - 0.26 10.6 5.9 31 4.0 0.0 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF3104) Profilin PF00235.14 KFM03871.1 - 3.8e-19 68.9 0.0 4.4e-19 68.7 0.0 1.0 1 0 0 1 1 1 1 Profilin ADH_zinc_N PF00107.21 KFM03873.1 - 5.1e-23 81.0 0.1 1e-22 80.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFM03873.1 - 2.4e-16 60.7 0.0 1.1e-15 58.7 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFM03873.1 - 1.6e-10 40.7 0.1 1.6e-08 34.2 0.0 2.6 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain RVT_1 PF00078.22 KFM03874.1 - 0.082 12.2 0.0 0.25 10.6 0.0 1.7 1 1 1 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) RRM_1 PF00076.17 KFM03875.1 - 3.2e-16 58.7 0.2 2.3e-15 55.9 0.0 2.2 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM03875.1 - 2.7e-11 43.2 0.0 5.8e-11 42.2 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM03875.1 - 7.8e-09 35.2 0.0 1.7e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3791 PF12668.2 KFM03875.1 - 0.044 13.4 0.2 1.2 8.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3791) FKBP_C PF00254.23 KFM03876.1 - 2.1e-27 94.9 0.0 2.3e-27 94.8 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF4613 PF15390.1 KFM03878.1 - 0 1044.7 0.0 0 1044.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4613) DUF4613 PF15390.1 KFM03879.1 - 0 1026.1 0.0 0 1025.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4613) MFS_2 PF13347.1 KFM03880.1 - 3.1e-88 296.0 20.1 3.5e-88 295.8 14.0 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.11 KFM03880.1 - 3.6e-10 39.0 25.3 1e-07 31.0 4.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3099 PF11298.3 KFM03880.1 - 0.69 9.6 3.5 6.7 6.5 2.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) SEP PF08059.8 KFM03881.1 - 1.8e-27 95.4 0.5 4.5e-27 94.1 0.1 1.8 2 0 0 2 2 2 1 SEP domain UBX PF00789.15 KFM03881.1 - 5.2e-14 52.0 0.0 1.3e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 UBX domain Spt20 PF12090.3 KFM03881.1 - 0.0027 17.0 0.0 0.0035 16.7 0.0 1.5 1 1 0 1 1 1 1 Spt20 family AAA PF00004.24 KFM03882.1 - 1.2e-47 161.4 0.0 7.7e-41 139.3 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.20 KFM03882.1 - 4.6e-18 64.9 0.1 1.1e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 Bromodomain AAA_16 PF13191.1 KFM03882.1 - 4.7e-08 33.2 0.7 1.9e-05 24.7 0.0 3.2 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KFM03882.1 - 5.2e-06 26.6 0.1 0.0033 17.5 0.1 3.6 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KFM03882.1 - 8.4e-06 25.3 0.0 6.4e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.9 KFM03882.1 - 7.9e-05 22.6 0.0 0.00026 20.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.1 KFM03882.1 - 0.00025 21.0 0.0 0.57 10.2 0.0 3.3 2 1 1 3 3 3 1 Sigma-54 interaction domain AAA_19 PF13245.1 KFM03882.1 - 0.00046 19.8 0.0 0.032 13.9 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 KFM03882.1 - 0.0031 17.8 0.7 0.036 14.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KFM03882.1 - 0.0038 18.0 1.4 0.014 16.1 0.0 2.8 2 1 1 3 3 1 1 AAA domain AAA_5 PF07728.9 KFM03882.1 - 0.0038 16.9 0.1 0.046 13.4 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 KFM03882.1 - 0.011 15.9 0.0 0.048 13.8 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.16 KFM03882.1 - 0.011 14.8 0.0 0.2 10.7 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 KFM03882.1 - 0.015 14.3 0.0 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 KFM03882.1 - 0.02 14.2 0.0 0.055 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 KFM03882.1 - 0.033 13.2 0.0 0.091 11.7 0.0 1.8 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 KFM03882.1 - 0.038 13.8 0.1 0.2 11.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.8 KFM03882.1 - 0.04 12.6 0.0 0.14 10.8 0.0 1.8 2 0 0 2 2 2 0 TIP49 C-terminus AAA_28 PF13521.1 KFM03882.1 - 0.052 13.5 0.4 0.27 11.1 0.0 2.4 3 0 0 3 3 2 0 AAA domain NACHT PF05729.7 KFM03882.1 - 0.059 13.0 0.0 0.38 10.3 0.0 2.4 2 1 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.21 KFM03882.1 - 0.062 12.7 0.0 0.79 9.1 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.1 KFM03882.1 - 0.17 11.4 0.0 0.55 9.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain Rnk_N PF14760.1 KFM03885.1 - 0.25 11.4 1.9 16 5.6 0.3 2.5 1 1 1 2 2 2 0 Rnk N-terminus Kelch_1 PF01344.20 KFM03886.1 - 6e-48 160.1 11.7 1.9e-13 49.7 0.0 7.0 7 1 0 7 7 7 5 Kelch motif Kelch_6 PF13964.1 KFM03886.1 - 2.4e-46 154.0 8.9 5.3e-11 42.1 0.0 6.4 1 1 5 6 6 6 6 Kelch motif BACK PF07707.10 KFM03886.1 - 4.5e-31 106.7 0.3 9.9e-31 105.6 0.2 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_4 PF13418.1 KFM03886.1 - 7.1e-29 99.3 3.4 1.1e-09 37.8 0.0 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain BTB PF00651.26 KFM03886.1 - 4.7e-24 84.5 0.9 1.1e-23 83.3 0.6 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.10 KFM03886.1 - 5.6e-23 79.7 2.8 8.5e-06 25.3 0.0 6.8 6 1 1 7 7 7 4 Kelch motif Kelch_5 PF13854.1 KFM03886.1 - 2.7e-18 65.5 11.9 0.00068 19.5 0.1 7.0 7 0 0 7 7 7 4 Kelch motif Kelch_3 PF13415.1 KFM03886.1 - 2.9e-18 65.4 4.6 1.8e-05 24.7 0.0 6.4 6 0 0 6 6 6 3 Galactose oxidase, central domain DUF1668 PF07893.8 KFM03886.1 - 0.0038 16.4 0.0 0.075 12.1 0.0 2.5 2 1 1 3 3 3 1 Protein of unknown function (DUF1668) DUF3342 PF11822.3 KFM03886.1 - 0.025 13.7 0.5 0.046 12.8 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) PQQ_3 PF13570.1 KFM03886.1 - 0.27 11.5 3.9 42 4.6 0.0 4.1 4 0 0 4 4 4 0 PQQ-like domain Hexapep PF00132.19 KFM03887.1 - 0.035 13.6 1.8 8.8 6.0 0.1 3.2 2 1 0 2 2 2 0 Bacterial transferase hexapeptide (six repeats) MatC_N PF07158.6 KFM03887.1 - 6.5 6.5 7.3 4.7 7.0 0.6 3.3 3 1 0 3 3 3 0 Dicarboxylate carrier protein MatC N-terminus TPD52 PF04201.10 KFM03888.1 - 1.7e-54 183.9 3.5 1.4e-53 180.9 2.4 1.9 1 1 0 1 1 1 1 Tumour protein D52 family GOLGA2L5 PF15070.1 KFM03888.1 - 0.027 12.9 0.3 0.038 12.4 0.2 1.2 1 1 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 VASP_tetra PF08776.6 KFM03888.1 - 0.16 11.3 1.2 0.62 9.4 0.9 1.9 2 0 0 2 2 2 0 VASP tetramerisation domain GAS PF13851.1 KFM03888.1 - 0.36 9.9 2.0 0.55 9.3 1.4 1.3 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DnaJ PF00226.26 KFM03889.1 - 3.9e-27 93.7 2.6 5.9e-27 93.1 1.8 1.3 1 0 0 1 1 1 1 DnaJ domain GP41 PF00517.12 KFM03889.1 - 0.0043 16.6 0.0 0.0085 15.6 0.0 1.4 2 0 0 2 2 2 1 Retroviral envelope protein Sigma70_ner PF04546.8 KFM03889.1 - 0.089 12.3 0.0 0.089 12.3 0.0 1.5 2 0 0 2 2 2 0 Sigma-70, non-essential region Corona_S2 PF01601.11 KFM03889.1 - 4.4 5.2 14.0 6 4.8 9.7 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein PRK PF00485.13 KFM03890.1 - 1.2e-57 194.5 0.0 1.4e-57 194.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CPT PF07931.7 KFM03890.1 - 2.3e-07 30.6 0.1 3.6e-07 29.9 0.1 1.5 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.1 KFM03890.1 - 2.8e-07 31.3 0.1 5.7e-07 30.3 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFM03890.1 - 3.8e-06 27.2 0.0 5.6e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFM03890.1 - 0.00044 20.1 0.0 0.00078 19.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain CoaE PF01121.15 KFM03890.1 - 0.0075 15.6 0.0 0.17 11.2 0.0 2.1 2 0 0 2 2 2 1 Dephospho-CoA kinase Zeta_toxin PF06414.7 KFM03890.1 - 0.027 13.5 0.0 0.067 12.2 0.0 1.6 1 1 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 KFM03890.1 - 0.035 13.8 0.0 2.1 8.1 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain zf-C2H2_4 PF13894.1 KFM03891.1 - 4.3e-10 39.1 42.5 0.011 15.9 0.5 8.5 8 0 0 8 8 8 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM03891.1 - 5.9e-10 38.9 22.1 0.018 15.1 0.2 6.3 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 KFM03891.1 - 3.4e-08 33.3 48.9 0.0098 16.1 0.5 8.4 8 0 0 8 8 8 4 Zinc finger, C2H2 type zf-BED PF02892.10 KFM03891.1 - 9.7e-05 22.0 36.1 0.23 11.2 0.4 6.6 4 2 2 6 6 6 4 BED zinc finger CpXC PF14353.1 KFM03891.1 - 0.00041 20.2 18.8 0.29 11.0 1.9 4.7 3 1 1 4 4 4 3 CpXC protein zf-met PF12874.2 KFM03891.1 - 0.0013 18.8 24.5 0.75 10.0 0.2 5.9 5 0 0 5 5 5 3 Zinc-finger of C2H2 type DUF629 PF04780.7 KFM03891.1 - 0.0023 16.5 11.4 4.2 5.7 0.2 4.2 4 0 0 4 4 4 4 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.2 KFM03891.1 - 0.0036 17.3 30.7 0.26 11.4 0.4 6.2 3 2 2 6 6 6 3 C2H2 type zinc-finger (2 copies) zf-FCS PF06467.9 KFM03891.1 - 0.0086 15.6 13.0 0.061 12.9 0.2 4.2 4 0 0 4 4 4 2 MYM-type Zinc finger with FCS sequence motif zf-Di19 PF05605.7 KFM03891.1 - 0.017 15.2 25.1 0.14 12.3 0.7 5.4 5 0 0 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zf-Nse PF11789.3 KFM03891.1 - 1.3 8.5 8.3 2.5 7.7 0.1 4.1 4 0 0 4 4 4 0 Zinc-finger of the MIZ type in Nse subunit zf-C2H2_6 PF13912.1 KFM03891.1 - 5.3 7.1 22.9 3.9 7.5 0.2 5.2 5 0 0 5 5 5 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 KFM03891.1 - 5.6 7.0 26.3 5.3 7.0 1.7 6.0 5 0 0 5 5 5 0 Zinc ribbon domain PyrI_C PF02748.10 KFM03891.1 - 7.4 6.0 36.7 0.71 9.3 0.6 6.2 5 2 0 5 5 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain SAM_2 PF07647.12 KFM03892.1 - 9.5e-18 63.8 0.4 1.3e-17 63.3 0.3 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFM03892.1 - 8.3e-09 35.4 0.2 1.4e-08 34.7 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 KFM03892.1 - 1e-05 25.1 0.0 1.7e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain PilI PF10623.4 KFM03892.1 - 0.02 14.8 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 Plasmid conjugative transfer protein PilI C8 PF08742.6 KFM03893.1 - 8 6.7 24.1 4.8 7.5 1.5 4.1 1 1 3 4 4 4 0 C8 domain PRP1_N PF06424.7 KFM03894.1 - 6.5e-39 133.2 8.2 6.5e-39 133.2 5.7 1.8 2 0 0 2 2 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 KFM03894.1 - 2e-32 108.7 22.0 0.0013 19.2 0.0 13.7 6 3 8 14 14 14 9 Tetratricopeptide repeat TPR_19 PF14559.1 KFM03894.1 - 1.1e-22 80.0 8.2 4e-06 27.0 0.1 9.6 9 2 1 10 10 10 4 Tetratricopeptide repeat TPR_16 PF13432.1 KFM03894.1 - 5.8e-19 68.2 19.2 0.0038 17.8 0.0 8.9 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_17 PF13431.1 KFM03894.1 - 2.6e-10 39.6 3.2 0.084 13.1 0.0 8.5 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFM03894.1 - 6.8e-09 34.9 14.4 0.25 11.3 0.0 10.1 11 1 1 12 12 12 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFM03894.1 - 3.8e-08 32.8 15.8 0.0046 16.5 0.4 7.6 7 3 2 9 9 9 3 TPR repeat TPR_8 PF13181.1 KFM03894.1 - 3.5e-07 29.5 0.5 0.038 13.7 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat Suf PF05843.9 KFM03894.1 - 9.8e-07 28.7 4.0 0.047 13.4 0.0 6.0 5 1 1 7 7 7 1 Suppressor of forked protein (Suf) TPR_12 PF13424.1 KFM03894.1 - 9.6e-05 22.2 6.5 6 6.8 0.0 6.6 5 1 3 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFM03894.1 - 0.00018 20.9 1.2 1.7 8.3 0.1 5.1 6 0 0 6 6 6 2 Tetratricopeptide repeat OsmC PF02566.14 KFM03894.1 - 0.033 14.3 2.5 13 6.0 0.0 5.2 6 0 0 6 6 6 0 OsmC-like protein TPR_6 PF13174.1 KFM03894.1 - 1.9 9.1 13.5 2.5e+02 2.4 0.0 8.3 13 0 0 13 13 9 0 Tetratricopeptide repeat TFIIS_M PF07500.9 KFM03896.1 - 1.7e-38 131.2 5.8 1.8e-38 131.1 1.7 2.1 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain Med26 PF08711.6 KFM03896.1 - 1.3e-19 69.4 1.1 4.4e-19 67.7 0.8 2.0 1 0 0 1 1 1 1 TFIIS helical bundle-like domain TFIIS_C PF01096.13 KFM03896.1 - 1.2e-18 66.4 8.2 2.4e-18 65.4 5.7 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) DBD_Tnp_Mut PF03108.10 KFM03896.1 - 0.046 13.3 0.7 0.13 11.8 0.5 1.8 1 0 0 1 1 1 0 MuDR family transposase Phage_XkdX PF09693.5 KFM03896.1 - 0.046 13.2 0.1 0.15 11.5 0.0 1.9 2 0 0 2 2 2 0 Phage uncharacterised protein (Phage_XkdX) Talin_middle PF09141.5 KFM03896.1 - 0.093 12.3 3.2 0.37 10.4 0.1 2.7 3 0 0 3 3 3 0 Talin, middle domain TF_Zn_Ribbon PF08271.7 KFM03896.1 - 0.25 10.7 4.6 0.81 9.0 2.8 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding RGS PF00615.14 KFM03897.1 - 5e-17 62.1 0.3 6.3e-17 61.7 0.2 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain 7tm_1 PF00001.16 KFM03898.1 - 1.2e-64 217.9 18.0 1.7e-64 217.4 12.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM03898.1 - 8.4e-14 51.3 18.9 1.3e-13 50.7 13.1 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 KFM03898.1 - 3.2e-08 33.0 6.8 3.2e-08 33.0 4.7 2.1 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.4 KFM03898.1 - 4.3e-05 22.7 17.5 4.3e-05 22.7 12.1 2.0 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Dispanin PF04505.7 KFM03898.1 - 2 7.9 7.6 0.26 10.8 0.1 3.1 4 0 0 4 4 4 0 Interferon-induced transmembrane protein Herpes_US9 PF06072.6 KFM03898.1 - 6.4 6.6 8.3 0.27 11.0 0.5 2.6 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 zf-C2HC PF01530.13 KFM03899.1 - 8.2e-102 332.5 79.3 3.2e-16 58.7 3.8 7.5 7 0 0 7 7 7 7 Zinc finger, C2HC type MYT1 PF08474.6 KFM03899.1 - 5.4e-90 301.3 21.1 1.5e-64 217.9 10.5 5.0 3 2 1 4 4 4 2 Myelin transcription factor 1 DUF1664 PF07889.7 KFM03899.1 - 0.56 9.9 3.6 1.4 8.7 2.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) zf-RING-like PF08746.6 KFM03899.1 - 1.6 8.7 22.7 2.4 8.2 0.1 7.1 7 0 0 7 7 7 0 RING-like domain AAA_23 PF13476.1 KFM03899.1 - 5.3 7.3 24.5 0.37 11.1 1.8 2.8 2 0 0 2 2 2 0 AAA domain Ly49 PF08391.5 KFM03899.1 - 7.5 6.7 8.3 26 4.9 0.0 2.9 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region PCMT PF01135.14 KFM03900.1 - 3.5e-26 92.0 0.0 4.8e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SOCS_box PF07525.11 KFM03900.1 - 9.3e-07 28.6 5.4 0.02 14.7 1.5 2.5 2 0 0 2 2 2 2 SOCS box DOT1 PF08123.8 KFM03900.1 - 0.00015 21.1 0.0 0.00026 20.3 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.1 KFM03900.1 - 0.00017 21.2 0.0 0.00036 20.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFM03900.1 - 0.00031 21.2 0.0 0.00079 19.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFM03900.1 - 0.0074 16.7 1.1 0.015 15.7 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain GCD14 PF08704.5 KFM03900.1 - 0.0086 15.5 0.3 0.019 14.5 0.0 1.6 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit UPF0150 PF03681.10 KFM03900.1 - 0.13 11.8 0.1 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0150) An_peroxidase PF03098.10 KFM03902.1 - 2.1e-184 613.8 0.0 2.8e-184 613.4 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase I-set PF07679.11 KFM03902.1 - 1.9e-84 277.6 0.0 8.7e-21 73.5 0.0 4.3 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM03902.1 - 2.9e-54 181.1 0.0 1e-13 51.1 0.0 4.5 4 0 0 4 4 4 4 Immunoglobulin domain Ig_3 PF13927.1 KFM03902.1 - 1.2e-36 124.9 0.2 5.9e-09 36.3 0.6 4.6 4 0 0 4 4 4 4 Immunoglobulin domain LRR_8 PF13855.1 KFM03902.1 - 4.9e-34 115.8 31.9 1.6e-14 53.3 5.8 3.7 1 1 2 3 3 3 3 Leucine rich repeat V-set PF07686.12 KFM03902.1 - 1.3e-27 95.9 0.0 2.6e-06 27.3 0.0 5.4 4 2 0 4 4 4 4 Immunoglobulin V-set domain ig PF00047.20 KFM03902.1 - 4.7e-27 93.8 0.3 1.1e-06 28.5 0.1 4.9 4 1 0 4 4 4 4 Immunoglobulin domain LRR_4 PF12799.2 KFM03902.1 - 3.5e-19 67.9 22.4 2.5e-07 30.1 0.9 4.5 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) C2-set_2 PF08205.7 KFM03902.1 - 7.7e-14 51.3 0.1 0.053 13.4 0.0 4.5 4 0 0 4 4 4 4 CD80-like C2-set immunoglobulin domain LRR_5 PF13306.1 KFM03902.1 - 8.7e-12 44.8 0.3 2.1e-11 43.6 0.2 1.6 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_1 PF00560.28 KFM03902.1 - 2.5e-06 26.7 22.5 1.1 9.5 0.3 7.3 6 0 0 6 6 6 4 Leucine Rich Repeat LRR_9 PF14580.1 KFM03902.1 - 3.4e-06 26.7 3.6 0.0051 16.3 0.5 2.3 1 1 1 2 2 2 2 Leucine-rich repeat Sp38 PF07354.7 KFM03902.1 - 5.2e-05 22.0 1.7 0.087 11.4 0.0 3.4 4 0 0 4 4 3 2 Zona-pellucida-binding protein (Sp38) B_lectin PF01453.19 KFM03902.1 - 0.0057 16.5 0.0 27 4.7 0.0 3.3 3 0 0 3 3 3 0 D-mannose binding lectin Herpes_gE PF02480.11 KFM03902.1 - 0.026 12.8 0.0 0.14 10.4 0.0 2.0 1 1 0 2 2 2 0 Alphaherpesvirus glycoprotein E LRR_7 PF13504.1 KFM03902.1 - 1.7 9.2 17.5 23 5.7 0.1 6.5 6 0 0 6 6 6 0 Leucine rich repeat Pkinase_Tyr PF07714.12 KFM03903.1 - 1.4e-94 315.9 0.0 1.8e-94 315.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM03903.1 - 1.1e-51 175.4 0.0 1.6e-51 174.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 KFM03903.1 - 1.9e-23 82.0 0.0 4.5e-23 80.8 0.0 1.7 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.1 KFM03903.1 - 5.2e-09 35.5 0.0 1.2e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM03903.1 - 1.5e-06 27.5 0.0 2.7e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain RIO1 PF01163.17 KFM03903.1 - 0.0013 18.1 0.1 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 KFM03903.1 - 0.0033 16.4 0.0 0.0053 15.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like SH3_2 PF07653.12 KFM03903.1 - 0.013 14.9 0.0 0.032 13.7 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain Kdo PF06293.9 KFM03903.1 - 0.028 13.4 0.3 0.076 12.0 0.2 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFM03903.1 - 0.066 12.9 0.0 2.9 7.5 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KFM03903.1 - 0.19 11.0 0.2 0.68 9.2 0.0 1.8 1 1 1 2 2 2 0 PhoP regulatory network protein YrbL PPDFL PF15060.1 KFM03904.1 - 5.6e-45 151.8 4.7 6.1e-45 151.7 3.3 1.0 1 0 0 1 1 1 1 Differentiation and proliferation regulator GTP_EFTU PF00009.22 KFM03905.1 - 1.2e-57 194.4 0.0 1.7e-57 193.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KFM03905.1 - 1.6e-35 121.2 0.0 4.2e-35 119.8 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KFM03905.1 - 2.1e-17 63.0 2.1 2.3e-17 62.8 0.4 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 KFM03905.1 - 4e-05 23.1 0.1 0.00014 21.4 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 KFM03905.1 - 0.00051 19.9 0.4 0.0015 18.5 0.3 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KFM03905.1 - 0.024 14.4 0.1 8.6 6.1 0.1 2.5 2 0 0 2 2 2 0 Dynamin family KCNQ_channel PF03520.9 KFM03906.1 - 4.1e-66 222.1 0.0 4.1e-51 173.1 0.0 2.3 2 0 0 2 2 2 2 KCNQ voltage-gated potassium channel KCNQC3-Ank-G_bd PF11956.3 KFM03906.1 - 3.2e-41 139.4 1.0 6.5e-41 138.5 0.7 1.5 1 0 0 1 1 1 1 Ankyrin-G binding motif of KCNQ2-3 Ion_trans PF00520.26 KFM03906.1 - 1.5e-27 96.1 6.7 3.2e-27 95.1 4.6 1.6 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.11 KFM03906.1 - 4.3e-13 48.7 3.3 1.2e-12 47.3 2.3 1.8 1 0 0 1 1 1 1 Ion channel Neur_chan_memb PF02932.11 KFM03907.1 - 9e-101 336.7 4.4 1.3e-100 336.2 3.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 KFM03907.1 - 2.5e-59 200.0 6.2 3.4e-59 199.6 4.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF3119 PF11317.3 KFM03907.1 - 0.007 16.3 2.7 0.007 16.3 1.9 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3119) fn3 PF00041.16 KFM03908.1 - 1.2e-77 256.1 19.1 1.1e-15 57.5 0.4 6.4 6 0 0 6 6 6 6 Fibronectin type III domain VWA PF00092.23 KFM03908.1 - 5.8e-49 166.2 0.0 1e-48 165.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Collagen PF01391.13 KFM03908.1 - 6.6e-40 134.4 158.1 1.4e-09 37.3 24.4 5.3 2 2 3 5 5 5 5 Collagen triple helix repeat (20 copies) VWA_2 PF13519.1 KFM03908.1 - 1.5e-12 47.9 0.2 1e-11 45.2 0.0 2.3 3 0 0 3 3 3 1 von Willebrand factor type A domain SusE PF14292.1 KFM03908.1 - 0.00036 20.3 1.6 10 5.9 0.0 5.6 6 1 1 7 7 7 2 SusE outer membrane protein CBM_4_9 PF02018.12 KFM03908.1 - 0.0004 20.3 3.2 0.0045 17.0 0.1 3.6 3 1 0 4 4 4 1 Carbohydrate binding domain DUF2369 PF10179.4 KFM03908.1 - 0.059 12.4 0.0 17 4.3 0.0 3.4 4 0 0 4 4 4 0 Uncharacterised conserved protein (DUF2369) DEP PF00610.16 KFM03909.1 - 9.7e-45 150.1 0.8 4.7e-22 77.5 0.1 2.3 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PDZ PF00595.19 KFM03909.1 - 0.083 13.0 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) ArfGap PF01412.13 KFM03910.1 - 8e-34 115.9 0.5 8e-34 115.9 0.3 2.4 2 1 1 3 3 3 1 Putative GTPase activating protein for Arf zf-piccolo PF05715.8 KFM03910.1 - 0.019 14.9 0.8 0.04 13.9 0.6 1.4 1 0 0 1 1 1 0 Piccolo Zn-finger Ribosomal_L37ae PF01780.14 KFM03910.1 - 0.038 13.8 0.2 0.14 12.0 0.1 2.0 2 0 0 2 2 2 0 Ribosomal L37ae protein family NKAIN PF05640.9 KFM03911.1 - 1.5e-87 291.7 4.4 1.7e-87 291.5 3.0 1.0 1 0 0 1 1 1 1 Na,K-Atpase Interacting protein DUF1003 PF06210.6 KFM03911.1 - 4.1 7.3 6.4 13 5.7 4.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1003) BIR PF00653.16 KFM03912.1 - 1.6e-44 150.1 13.7 1.1e-24 86.5 0.5 2.9 3 0 0 3 3 3 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.1 KFM03912.1 - 8.9e-15 54.1 7.5 8.9e-15 54.1 5.2 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM03912.1 - 1.1e-05 25.3 8.8 1.1e-05 25.3 6.1 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM03912.1 - 0.00075 19.1 6.7 0.00075 19.1 4.7 2.4 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.1 KFM03912.1 - 0.038 13.5 6.0 0.12 11.9 4.2 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 DUF2039 PF10217.4 KFM03912.1 - 0.091 12.7 2.0 0.21 11.6 1.4 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) GAGA PF09237.6 KFM03912.1 - 0.12 11.9 2.7 0.14 11.8 0.6 2.0 2 0 0 2 2 2 0 GAGA factor YTH PF04146.10 KFM03913.1 - 5.4e-49 165.4 0.1 7.7e-49 164.8 0.1 1.2 1 0 0 1 1 1 1 YT521-B-like domain HLH PF00010.21 KFM03914.1 - 7.2e-15 54.4 0.4 2.8e-14 52.5 0.2 1.8 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain MFS_1 PF07690.11 KFM03915.1 - 1.4e-45 155.5 27.2 1.4e-45 155.5 18.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ESSS PF10183.4 KFM03915.1 - 0.59 10.5 2.9 0.55 10.6 0.7 1.9 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) CLTH PF10607.4 KFM03916.1 - 2.9e-36 124.3 6.1 3.8e-36 123.9 4.2 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 KFM03916.1 - 8.4e-13 47.5 0.4 3.1e-11 42.6 0.1 2.6 2 0 0 2 2 2 1 LisH FlaF PF07309.6 KFM03916.1 - 0.016 15.0 1.5 0.032 14.0 1.1 1.5 1 0 0 1 1 1 0 Flagellar protein FlaF TFIIS_M PF07500.9 KFM03918.1 - 7.3e-34 116.2 2.6 7.3e-34 116.2 1.8 2.8 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 KFM03918.1 - 4.5e-20 72.3 0.0 1.5e-19 70.6 0.0 2.0 1 0 0 1 1 1 1 SPOC domain PHD PF00628.24 KFM03918.1 - 6.1e-12 45.0 8.2 1.4e-11 43.8 5.7 1.7 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.1 KFM03918.1 - 1.3 9.2 5.0 0.58 10.4 0.2 3.1 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx HLH PF00010.21 KFM03919.1 - 1.7e-09 37.2 0.2 2.5e-08 33.4 0.1 2.4 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Collagen PF01391.13 KFM03920.1 - 2.7e-18 65.2 58.5 1.6e-10 40.3 21.2 2.4 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) OGFr_N PF04664.8 KFM03921.1 - 4.5e-94 313.7 7.4 6.8e-94 313.1 5.1 1.2 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region Eaf7 PF07904.8 KFM03922.1 - 1.5e-17 63.3 0.1 3.8e-17 62.0 0.1 1.7 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 Asp-B-Hydro_N PF05279.6 KFM03922.1 - 0.022 14.6 4.5 0.025 14.4 3.1 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region RAP1 PF07218.6 KFM03922.1 - 0.51 8.3 4.0 0.62 8.1 2.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Vfa1 PF08432.5 KFM03922.1 - 1.7 8.6 7.6 2.2 8.2 5.3 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 7tm_1 PF00001.16 KFM03923.1 - 2.1e-14 53.3 13.2 2.8e-14 52.9 9.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) OATP PF03137.15 KFM03924.1 - 8.6e-168 558.7 11.5 1.2e-167 558.2 8.0 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 KFM03924.1 - 5.5e-16 58.2 26.1 5.5e-16 58.2 18.1 2.7 2 2 0 2 2 2 1 Major Facilitator Superfamily Kazal_2 PF07648.10 KFM03924.1 - 8.3e-09 35.2 7.1 8.3e-09 35.2 4.9 2.5 2 1 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 KFM03924.1 - 0.018 15.0 8.7 0.061 13.3 6.0 1.9 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain GATA PF00320.22 KFM03925.1 - 1.9e-31 107.1 16.2 1.5e-16 59.3 3.6 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 KFM03925.1 - 6.9e-05 22.0 9.5 0.028 13.7 2.3 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding eIF-5_eIF-2B PF01873.12 KFM03925.1 - 0.00091 18.8 2.8 0.29 10.7 0.4 2.5 2 0 0 2 2 2 2 Domain found in IF2B/IF5 ArfGap PF01412.13 KFM03925.1 - 0.001 18.8 1.4 0.11 12.2 0.1 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf DUF2387 PF09526.5 KFM03925.1 - 0.022 14.6 5.5 3.5 7.6 0.2 3.0 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) Elf1 PF05129.8 KFM03925.1 - 0.034 13.8 4.0 0.93 9.2 0.0 2.6 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.2 KFM03925.1 - 0.035 13.9 0.3 0.035 13.9 0.2 2.7 2 1 1 3 3 3 0 Transposase zinc-ribbon domain DZR PF12773.2 KFM03925.1 - 0.062 13.1 9.8 8.2 6.3 1.7 2.7 1 1 1 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 KFM03925.1 - 0.065 13.2 5.9 0.86 9.6 0.9 3.1 3 0 0 3 3 3 0 Zinc ribbon domain BaffR-Tall_bind PF09256.5 KFM03925.1 - 0.1 12.2 4.5 1.7 8.3 0.0 3.3 3 0 0 3 3 3 0 BAFF-R, TALL-1 binding zf-ribbon_3 PF13248.1 KFM03925.1 - 0.2 10.9 8.7 1.2 8.4 0.6 3.3 3 1 0 3 3 3 0 zinc-ribbon domain C1_1 PF00130.17 KFM03925.1 - 1.1 9.0 6.1 15 5.3 0.3 3.1 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) OrfB_Zn_ribbon PF07282.6 KFM03925.1 - 1.1 8.9 9.5 1.3 8.7 0.4 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Cytochrom_c3_2 PF14537.1 KFM03925.1 - 1.2 9.5 6.8 2 8.8 4.1 1.8 1 1 1 2 2 2 0 Cytochrome c3 Cytochrome_C7 PF14522.1 KFM03925.1 - 7.3 6.3 11.2 41 3.9 7.9 2.1 1 1 0 1 1 1 0 Cytochrome c7 CtIP_N PF10482.4 KFM03926.1 - 7.8e-54 180.5 18.9 7.8e-54 180.5 13.1 1.6 2 0 0 2 2 2 1 Tumour-suppressor protein CtIP N-terminal domain DivIC PF04977.10 KFM03926.1 - 0.032 13.7 14.9 0.068 12.6 0.7 3.3 2 1 1 3 3 3 0 Septum formation initiator DUF904 PF06005.7 KFM03926.1 - 0.18 12.1 27.8 0.17 12.1 7.2 3.5 4 0 0 4 4 3 0 Protein of unknown function (DUF904) Raffinose_syn PF05691.7 KFM03926.1 - 0.27 8.7 0.1 0.37 8.2 0.0 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 DUF4618 PF15397.1 KFM03926.1 - 0.28 10.5 16.2 0.33 10.2 1.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DUF4407 PF14362.1 KFM03926.1 - 0.65 8.9 6.4 1.1 8.1 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMF_TATA_bd PF12325.3 KFM03926.1 - 0.89 9.2 14.4 0.27 10.9 2.8 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF972 PF06156.8 KFM03926.1 - 2.1 8.7 19.1 5.3 7.4 5.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF972) bZIP_1 PF00170.16 KFM03926.1 - 2.2 8.2 21.1 0.49 10.3 1.4 3.6 3 1 1 4 4 3 0 bZIP transcription factor DUF342 PF03961.8 KFM03926.1 - 2.6 6.3 8.5 4.1 5.7 5.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DivIVA PF05103.8 KFM03926.1 - 6.8 6.7 18.5 3.1 7.8 2.1 3.0 2 1 1 3 3 3 0 DivIVA protein DUF3782 PF12644.2 KFM03926.1 - 7.4 6.4 11.6 2.7e+03 -1.8 8.6 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) TSC22 PF01166.13 KFM03926.1 - 7.7 6.5 11.4 5.6 7.0 0.7 3.7 2 1 1 3 3 3 0 TSC-22/dip/bun family Cyclin_N PF00134.18 KFM03927.1 - 1e-08 34.8 0.5 1.6e-08 34.1 0.3 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain HGTP_anticodon PF03129.15 KFM03927.1 - 0.1 12.5 0.0 0.5 10.3 0.0 2.0 2 0 0 2 2 2 0 Anticodon binding domain Proteasom_Rpn13 PF04683.8 KFM03928.1 - 1.1e-35 121.5 0.1 1.8e-35 120.8 0.1 1.4 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor ASXH PF13919.1 KFM03928.1 - 0.0054 16.5 0.1 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 Asx homology domain Hamartin PF04388.7 KFM03928.1 - 3.5 6.1 6.4 4.3 5.8 4.4 1.1 1 0 0 1 1 1 0 Hamartin protein Oxysterol_BP PF01237.13 KFM03929.1 - 2.8e-146 486.5 0.1 3.4e-146 486.2 0.1 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein 7tm_1 PF00001.16 KFM03930.1 - 5.9e-47 159.9 10.2 8.3e-47 159.4 7.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GTP1_OBG PF01018.17 KFM03931.1 - 1.6e-41 141.5 7.7 2.1e-41 141.1 5.3 1.1 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.18 KFM03931.1 - 4.8e-21 74.8 0.0 6.9e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFM03931.1 - 4.9e-12 45.4 0.0 1.1e-11 44.2 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 KFM03931.1 - 6.5e-05 23.4 0.0 0.00012 22.5 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM03931.1 - 0.00018 20.8 0.0 0.00028 20.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Dynamin_N PF00350.18 KFM03931.1 - 0.00019 21.2 0.0 0.13 12.0 0.0 2.2 1 1 1 2 2 2 2 Dynamin family Ras PF00071.17 KFM03931.1 - 0.014 14.8 0.0 0.029 13.7 0.0 1.6 1 1 0 1 1 1 0 Ras family ABC_tran PF00005.22 KFM03931.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Gtr1_RagA PF04670.7 KFM03931.1 - 0.2 10.7 0.0 0.28 10.2 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SSXT PF05030.7 KFM03932.1 - 1.1e-34 117.7 2.0 2.2e-34 116.8 1.4 1.5 1 0 0 1 1 1 1 SSXT protein (N-terminal region) DUF1313 PF07011.6 KFM03932.1 - 0.064 12.9 2.0 1.6 8.4 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1313) FDF PF09532.5 KFM03933.1 - 2e-29 102.1 9.7 2e-29 102.1 6.7 1.8 2 0 0 2 2 2 1 FDF domain LSM14 PF12701.2 KFM03933.1 - 8e-22 76.8 0.7 1.3e-21 76.1 0.0 1.7 2 0 0 2 2 2 1 Scd6-like Sm domain Cadherin PF00028.12 KFM03934.1 - 6.6e-86 282.7 6.1 1.9e-21 76.0 0.8 5.4 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.12 KFM03934.1 - 3.7e-35 121.1 0.6 3.7e-35 121.1 0.4 1.8 2 0 0 2 2 2 1 Cadherin cytoplasmic region Cadherin_pro PF08758.6 KFM03934.1 - 3e-17 62.1 0.0 2.1e-16 59.4 0.0 2.3 2 0 0 2 2 2 1 Cadherin prodomain like He_PIG PF05345.7 KFM03934.1 - 6.9e-05 22.7 7.9 0.02 14.9 0.2 5.1 5 0 0 5 5 5 1 Putative Ig domain Cadherin_2 PF08266.7 KFM03934.1 - 0.0023 17.4 0.0 7.8 6.1 0.0 3.5 3 0 0 3 3 3 2 Cadherin-like PKD PF00801.15 KFM03934.1 - 0.0055 16.4 2.4 0.47 10.2 0.1 4.1 4 0 0 4 4 4 1 PKD domain Rifin_STEVOR PF02009.11 KFM03934.1 - 0.14 11.7 0.6 0.28 10.8 0.4 1.4 1 0 0 1 1 1 0 Rifin/stevor family DUF3139 PF11337.3 KFM03934.1 - 0.16 12.2 0.2 0.38 11.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) FAM217 PF15344.1 KFM03936.1 - 5.5e-89 297.7 1.6 7.9e-89 297.2 1.1 1.2 1 0 0 1 1 1 1 FAM217 family CBM_21 PF03370.8 KFM03938.1 - 8.5e-33 112.7 0.1 1.2e-32 112.1 0.1 1.2 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit CBM_25 PF03423.8 KFM03938.1 - 0.018 15.1 2.3 0.23 11.5 1.6 2.4 1 1 0 1 1 1 0 Carbohydrate binding domain (family 25) Peptidase_M10_C PF08548.6 KFM03938.1 - 0.15 11.5 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase M10 serralysin C terminal RPEL PF02755.10 KFM03939.1 - 8.5e-26 88.5 20.6 4.9e-09 35.2 1.9 4.8 4 0 0 4 4 4 4 RPEL repeat Pkinase PF00069.20 KFM03940.1 - 1.7e-22 79.8 0.0 1.9e-22 79.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM03940.1 - 3.2e-08 32.9 0.0 3.5e-08 32.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase zf-H2C2_2 PF13465.1 KFM03942.1 - 4e-89 288.8 81.2 2.3e-09 37.0 0.5 12.6 13 0 0 13 13 13 12 Zinc-finger double domain zf-C2H2 PF00096.21 KFM03942.1 - 1.2e-71 232.9 87.6 2.1e-07 30.8 0.2 12.7 12 1 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KFM03942.1 - 5.3e-45 150.0 72.8 2e-05 24.3 0.4 12.6 12 2 0 12 12 12 11 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KFM03942.1 - 2.2e-39 130.8 74.6 4.7e-05 23.4 0.2 12.1 12 0 0 12 12 12 11 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM03942.1 - 1.4e-14 53.7 44.7 0.04 14.0 0.0 11.9 11 1 1 12 12 12 4 Zinc-finger double-stranded RNA-binding XPA_N PF01286.13 KFM03942.1 - 8e-10 38.2 33.1 3.5 7.3 0.0 11.8 12 0 0 12 12 12 1 XPA protein N-terminal Zn-ribbon_8 PF09723.5 KFM03942.1 - 3.9e-09 36.3 55.6 0.028 14.3 3.0 11.1 8 3 2 10 10 10 4 Zinc ribbon domain C1_4 PF07975.7 KFM03942.1 - 4.4e-07 29.7 36.1 0.59 10.1 0.1 9.2 2 1 6 8 8 8 3 TFIIH C1-like domain DNA_RNApol_7kD PF03604.8 KFM03942.1 - 4.9e-06 25.9 50.1 0.77 9.2 0.0 11.3 11 0 0 11 11 11 2 DNA directed RNA polymerase, 7 kDa subunit zf-Di19 PF05605.7 KFM03942.1 - 0.00023 21.2 40.7 0.0071 16.4 0.4 8.1 1 1 9 11 11 11 3 Drought induced 19 protein (Di19), zinc-binding RRN7 PF11781.3 KFM03942.1 - 0.0049 16.3 43.3 0.56 9.7 0.1 10.6 12 0 0 12 12 12 3 RNA polymerase I-specific transcription initiation factor Rrn7 zf-LYAR PF08790.6 KFM03942.1 - 0.0061 16.2 29.8 1.5 8.6 0.1 10.1 11 0 0 11 11 11 1 LYAR-type C2HC zinc finger Zn_ribbon_recom PF13408.1 KFM03942.1 - 0.012 15.8 67.5 0.19 12.0 2.0 9.6 2 2 8 10 10 9 0 Recombinase zinc beta ribbon domain FYDLN_acid PF09538.5 KFM03942.1 - 0.022 15.3 24.5 35 5.0 0.1 9.8 1 1 7 8 8 8 0 Protein of unknown function (FYDLN_acid) Elf1 PF05129.8 KFM03942.1 - 0.072 12.7 27.3 0.32 10.7 0.5 6.5 1 1 6 7 7 7 0 Transcription elongation factor Elf1 like zf-BED PF02892.10 KFM03942.1 - 0.22 11.3 0.1 0.22 11.3 0.0 10.5 2 2 9 11 11 11 0 BED zinc finger DrsE PF02635.10 KFM03942.1 - 0.26 11.3 0.6 2.2e+02 1.8 0.0 4.5 2 2 5 7 7 7 0 DsrE/DsrF-like family GAGA PF09237.6 KFM03942.1 - 0.74 9.4 29.0 1.5 8.4 0.0 6.9 4 3 3 8 8 8 0 GAGA factor Mu-like_Com PF10122.4 KFM03942.1 - 0.92 8.6 39.2 3.2 6.8 0.0 10.0 11 0 0 11 11 11 0 Mu-like prophage protein Com Yippee-Mis18 PF03226.9 KFM03942.1 - 1.1 9.3 31.9 1 9.4 2.1 6.8 2 2 3 5 5 5 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-AN1 PF01428.11 KFM03942.1 - 1.5 8.7 59.3 1.9 8.4 2.1 11.7 9 3 3 12 12 12 0 AN1-like Zinc finger zf-ISL3 PF14690.1 KFM03942.1 - 3.8 7.6 55.0 2.8 8.0 0.1 11.8 12 0 0 12 12 12 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 LIM PF00412.17 KFM03942.1 - 4.8 7.3 40.1 0.43 10.6 0.4 8.2 3 3 5 9 9 9 0 LIM domain E2F_TDP PF02319.15 KFM03944.1 - 9e-26 89.2 1.1 1.2e-25 88.8 0.1 1.7 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain B-block_TFIIIC PF04182.7 KFM03944.1 - 0.12 12.2 0.1 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC MBOAT PF03062.14 KFM03945.1 - 1.7e-30 106.2 10.4 1.7e-30 106.2 7.2 2.0 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Guanylate_cyc PF00211.15 KFM03946.1 - 1.7e-87 291.5 0.0 2.5e-57 193.2 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain DUF1053 PF06327.9 KFM03946.1 - 3.3e-25 88.3 0.1 1.1e-24 86.6 0.0 2.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1053) Vma12 PF11712.3 KFM03946.1 - 3.1 7.5 6.8 8.1 6.1 0.1 3.2 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase RVT_1 PF00078.22 KFM03947.1 - 0.0048 16.2 0.0 0.0059 15.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phospholip_A2_1 PF00068.14 KFM03949.1 - 6.1e-42 142.5 40.5 4.1e-22 78.6 12.4 2.2 2 0 0 2 2 2 2 Phospholipase A2 DUF717 PF05338.7 KFM03949.1 - 0.048 13.6 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF717) ATP-synt_ab PF00006.20 KFM03950.1 - 0.048 13.1 0.0 0.068 12.6 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain KCNQ_channel PF03520.9 KFM03951.1 - 5.1e-56 189.1 0.2 9.8e-56 188.2 0.1 1.4 1 0 0 1 1 1 1 KCNQ voltage-gated potassium channel KCNQC3-Ank-G_bd PF11956.3 KFM03951.1 - 2e-46 156.2 1.1 2e-46 156.2 0.8 1.9 2 0 0 2 2 2 1 Ankyrin-G binding motif of KCNQ2-3 Ion_trans PF00520.26 KFM03951.1 - 1e-23 83.6 1.0 1.8e-23 82.8 0.7 1.4 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.11 KFM03951.1 - 2.2e-12 46.5 0.5 5.4e-12 45.2 0.3 1.6 1 0 0 1 1 1 1 Ion channel Lig_chan PF00060.21 KFM03951.1 - 0.001 18.8 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 Ligand-gated ion channel LRR_4 PF12799.2 KFM03952.1 - 7.1e-13 47.8 25.7 7.7e-06 25.4 3.3 3.5 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 KFM03952.1 - 1.9e-11 43.8 1.6 3.6e-11 42.9 1.1 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 KFM03952.1 - 1.1e-09 37.8 13.5 6.4e-06 25.8 2.5 3.1 1 1 2 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 KFM03952.1 - 0.0015 18.2 4.3 35 4.9 0.1 5.2 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.1 KFM03952.1 - 0.5 10.5 2.4 84 3.7 0.0 3.9 2 1 1 3 3 3 0 Leucine Rich repeat TMEM71 PF15121.1 KFM03953.1 - 1.2e-64 216.6 1.0 1.6e-64 216.1 0.7 1.2 1 0 0 1 1 1 1 TMEM71 protein family DUF3099 PF11298.3 KFM03953.1 - 0.11 12.3 0.2 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) COesterase PF00135.23 KFM03955.1 - 1.3e-121 406.9 0.0 2e-121 406.3 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Thyroglobulin_1 PF00086.13 KFM03955.1 - 1.7e-84 277.1 84.8 6.5e-15 54.2 3.1 11.7 12 0 0 12 12 12 10 Thyroglobulin type-1 repeat GCC2_GCC3 PF07699.8 KFM03955.1 - 4e-11 42.3 5.7 4e-11 42.3 3.9 2.4 1 1 0 1 1 1 1 GCC2 and GCC3 Abhydrolase_3 PF07859.8 KFM03955.1 - 4.4e-05 23.1 0.1 8.6e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold SH2 PF00017.19 KFM03956.1 - 2.6e-21 75.2 0.4 6.4e-21 73.9 0.1 1.8 2 0 0 2 2 2 1 SH2 domain SH3_9 PF14604.1 KFM03956.1 - 1.5e-08 34.1 0.1 2.7e-08 33.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM03956.1 - 3.4e-07 29.5 0.0 6.9e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFM03956.1 - 0.0023 17.3 0.0 0.0045 16.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain IGFBP PF00219.13 KFM03957.1 - 5.7e-14 52.4 21.4 5.7e-14 52.4 14.9 5.0 4 3 0 4 4 4 1 Insulin-like growth factor binding protein TSP_1 PF00090.14 KFM03957.1 - 1.7e-09 37.6 4.7 1.7e-09 37.6 3.2 3.5 4 0 0 4 4 4 1 Thrombospondin type 1 domain Cys_knot PF00007.17 KFM03957.1 - 2.9e-09 36.9 8.2 2.9e-09 36.9 5.7 3.6 4 0 0 4 4 4 1 Cystine-knot domain VWC PF00093.13 KFM03957.1 - 2.1e-08 34.1 12.1 2.1e-08 34.1 8.4 5.1 4 3 0 4 4 4 1 von Willebrand factor type C domain Ndr PF03096.9 KFM03958.1 - 1.8e-124 413.8 0.0 2.2e-124 413.5 0.0 1.0 1 0 0 1 1 1 1 Ndr family Abhydrolase_6 PF12697.2 KFM03958.1 - 4.9e-15 56.0 0.0 6.7e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFM03958.1 - 0.00041 19.9 0.0 0.0041 16.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Glyco_transf_29 PF00777.13 KFM03959.1 - 1.7e-82 276.5 0.0 1.8e-82 276.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Yae1_N PF09811.4 KFM03960.1 - 2e-13 49.6 35.5 38 3.9 24.6 3.6 1 1 0 1 1 1 1 Essential protein Yae1, N terminal Annexin PF00191.15 KFM03961.1 - 9.8e-92 300.8 10.6 3.2e-27 94.1 0.4 4.1 4 0 0 4 4 4 4 Annexin Hormone_recep PF00104.25 KFM03962.1 - 9e-35 119.6 2.4 9e-35 119.6 1.6 1.7 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFM03962.1 - 3.8e-33 113.5 12.8 3.8e-33 113.5 8.9 2.3 3 0 0 3 3 3 1 Zinc finger, C4 type (two domains) DUF1162 PF06650.7 KFM03963.1 - 9.4e-67 225.1 0.1 4.6e-66 222.8 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1162) Chorein_N PF12624.2 KFM03963.1 - 3.7e-22 78.0 1.6 1.4e-21 76.1 0.2 2.9 3 0 0 3 3 3 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 KFM03963.1 - 8.9e-07 28.9 0.2 1.2e-05 25.3 0.0 3.0 3 0 0 3 3 3 1 ATG C terminal domain C2 PF00168.25 KFM03964.1 - 8.7e-09 35.1 0.0 1.7e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain Talin_middle PF09141.5 KFM03965.1 - 2.3e-73 245.1 5.7 2.3e-73 245.1 4.0 15.3 10 4 7 17 17 17 4 Talin, middle domain VBS PF08913.5 KFM03965.1 - 4.4e-69 230.5 106.3 2.7e-68 227.9 0.4 12.6 11 3 1 12 12 12 4 Vinculin Binding Site I_LWEQ PF01608.12 KFM03965.1 - 1.9e-59 199.9 184.6 2e-47 160.9 9.3 17.3 7 4 9 18 18 18 10 I/LWEQ domain FERM_N PF09379.5 KFM03965.1 - 1.2e-25 89.3 2.8 4.1e-24 84.4 0.3 3.3 3 0 0 3 3 3 1 FERM N-terminal domain FERM_M PF00373.13 KFM03965.1 - 1e-24 87.1 3.0 5.1e-24 84.8 0.0 3.4 2 0 0 2 2 2 1 FERM central domain IRS PF02174.12 KFM03965.1 - 4.9e-05 22.8 0.0 0.00012 21.6 0.0 1.6 1 0 0 1 1 1 1 PTB domain (IRS-1 type) NS3_envE PF02723.9 KFM03965.1 - 0.47 10.3 0.2 1 9.3 0.1 1.5 1 0 0 1 1 1 0 Non-structural protein NS3/Small envelope protein E DUF2605 PF10792.4 KFM03965.1 - 2.3 7.9 11.6 0.31 10.7 1.1 4.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2605) Tropomyosin PF00261.15 KFM03966.1 - 2.2e-106 354.2 85.8 5.9e-101 336.5 43.1 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.2 KFM03966.1 - 6.8e-40 136.2 77.7 5.2e-36 123.6 29.7 3.0 1 1 1 3 3 3 3 Tropomyosin like Laminin_II PF06009.7 KFM03966.1 - 3.3e-07 30.1 35.5 1.6e-05 24.6 4.7 3.8 1 1 3 4 4 4 3 Laminin Domain II TMF_DNA_bd PF12329.3 KFM03966.1 - 2.9e-05 23.7 9.8 2.9e-05 23.7 6.8 6.1 1 1 4 6 6 6 2 TATA element modulatory factor 1 DNA binding IncA PF04156.9 KFM03966.1 - 0.00082 19.0 63.1 0.0021 17.6 17.4 3.0 1 1 2 3 3 3 1 IncA protein CENP-F_leu_zip PF10473.4 KFM03966.1 - 0.0029 17.4 68.3 0.0037 17.1 21.6 2.2 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MscS_porin PF12795.2 KFM03966.1 - 0.0037 16.6 48.5 0.49 9.6 13.3 3.1 1 1 0 2 2 2 2 Mechanosensitive ion channel porin domain ATG16 PF08614.6 KFM03966.1 - 0.01 15.6 9.8 0.01 15.6 6.8 3.4 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) AAA_13 PF13166.1 KFM03966.1 - 0.014 13.8 51.0 0.0082 14.6 22.3 2.1 1 1 1 2 2 2 0 AAA domain Myosin_tail_1 PF01576.14 KFM03966.1 - 0.015 13.1 69.6 0.53 7.9 48.3 2.5 1 1 0 1 1 1 0 Myosin tail Laminin_I PF06008.9 KFM03966.1 - 0.088 12.1 53.1 0.17 11.1 8.5 3.1 1 1 2 3 3 3 0 Laminin Domain I DUF869 PF05911.6 KFM03966.1 - 0.14 10.3 54.7 0.28 9.3 16.5 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) WEMBL PF05701.6 KFM03966.1 - 0.29 9.5 70.7 0.13 10.6 13.9 3.7 1 1 1 3 3 3 0 Weak chloroplast movement under blue light Flagellin_N PF00669.15 KFM03966.1 - 0.3 10.8 17.2 0.42 10.4 0.3 3.6 1 1 2 3 3 3 0 Bacterial flagellin N-terminal helical region Nup54 PF13874.1 KFM03966.1 - 0.33 10.6 34.9 0.47 10.1 0.7 3.8 1 1 3 4 4 4 0 Nucleoporin complex subunit 54 Reo_sigmaC PF04582.7 KFM03966.1 - 0.34 10.0 10.3 0.5 9.4 1.0 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein SlyX PF04102.7 KFM03966.1 - 0.34 11.2 37.8 0.65 10.4 0.5 5.8 1 1 5 6 6 6 0 SlyX RmuC PF02646.11 KFM03966.1 - 0.66 8.7 30.9 0.14 10.9 3.9 3.9 1 1 3 4 4 4 0 RmuC family ADIP PF11559.3 KFM03966.1 - 0.81 9.5 53.6 3.5 7.5 6.1 4.1 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding Flagellin_C PF00700.16 KFM03966.1 - 1 9.5 15.8 0.78 9.9 1.1 4.3 1 1 3 5 5 5 0 Bacterial flagellin C-terminal helical region DUF745 PF05335.8 KFM03966.1 - 1.1 8.7 46.4 0.54 9.7 5.6 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF745) GAS PF13851.1 KFM03966.1 - 1.2 8.3 63.4 1.5 8.0 12.0 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding gpW PF02831.10 KFM03966.1 - 1.4 8.5 10.2 4.7 6.8 0.2 3.6 4 0 0 4 4 3 0 gpW DUF4200 PF13863.1 KFM03966.1 - 1.9 8.4 71.1 2.4 8.0 18.5 4.4 1 1 2 3 3 2 0 Domain of unknown function (DUF4200) AAA_27 PF13514.1 KFM03966.1 - 2.2 5.8 54.6 3.1 5.3 37.9 1.2 1 0 0 1 1 1 0 AAA domain ERM PF00769.14 KFM03966.1 - 4.2 6.8 71.9 0.03 13.8 16.3 2.9 1 1 2 3 3 3 0 Ezrin/radixin/moesin family NPV_P10 PF05531.7 KFM03966.1 - 4.3 7.6 19.3 10 6.4 0.5 4.5 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF3584 PF12128.3 KFM03966.1 - 4.3 4.5 58.0 2.2 5.4 16.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) EzrA PF06160.7 KFM03966.1 - 4.3 5.3 50.1 3.7 5.6 11.2 3.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Fib_alpha PF08702.5 KFM03966.1 - 4.4 7.4 34.4 1.2 9.2 4.3 3.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family COG2 PF06148.6 KFM03966.1 - 6.7 6.5 31.6 3.7 7.4 7.4 4.2 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 APG6 PF04111.7 KFM03966.1 - 8.2 5.3 65.6 0.37 9.8 15.6 3.1 1 1 2 3 3 3 0 Autophagy protein Apg6 FH2 PF02181.18 KFM03966.1 - 8.6 5.1 38.1 1.6 7.4 7.2 3.1 1 1 2 3 3 3 0 Formin Homology 2 Domain DUF4407 PF14362.1 KFM03966.1 - 9.1 5.1 43.3 1.2 8.0 17.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Beta-lactamase PF00144.19 KFM03967.1 - 7.4e-52 176.3 0.0 9.4e-28 97.1 0.0 2.0 2 0 0 2 2 2 2 Beta-lactamase Peptidase_S11 PF00768.15 KFM03967.1 - 0.017 14.4 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Ribosomal_S27e PF01667.12 KFM03968.1 - 7.1e-31 105.5 5.0 8.9e-31 105.2 3.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 KFM03968.1 - 0.011 15.6 1.9 0.013 15.3 1.3 1.2 1 0 0 1 1 1 0 IBR domain Carb_anhydrase PF00194.16 KFM03969.1 - 8.3e-72 241.2 0.0 9.9e-72 240.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase UCH PF00443.24 KFM03970.1 - 1.1e-68 231.2 0.7 2.2e-68 230.2 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFM03970.1 - 1e-27 97.3 0.4 6.7e-27 94.6 0.3 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KFM03970.1 - 5.5e-19 68.0 11.4 5.5e-19 68.0 7.9 2.9 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein LRR_6 PF13516.1 KFM03971.1 - 2.5e-07 30.0 4.4 0.034 14.1 0.0 3.8 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.2 KFM03971.1 - 0.00089 18.8 6.2 0.0024 17.4 2.0 3.1 3 1 1 4 4 4 1 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 KFM03971.1 - 0.0033 17.3 4.9 13 6.5 0.1 4.4 4 0 0 4 4 4 1 Leucine rich repeat LRR_1 PF00560.28 KFM03971.1 - 0.0057 16.5 4.7 19 5.8 0.0 4.1 3 0 0 3 3 3 0 Leucine Rich Repeat F-box-like PF12937.2 KFM03971.1 - 0.0086 15.7 0.3 0.016 14.9 0.2 1.5 1 0 0 1 1 1 1 F-box-like LRR_2 PF07723.8 KFM03971.1 - 0.19 12.2 7.2 6.2 7.4 0.0 4.3 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.1 KFM03971.1 - 0.21 11.3 5.7 0.21 11.3 1.3 2.8 2 1 2 4 4 4 0 Leucine rich repeat Adeno_E4_34 PF04528.8 KFM03971.1 - 0.58 9.7 5.4 1 8.9 1.2 2.3 1 1 1 2 2 2 0 Adenovirus early E4 34 kDa protein conserved region Pkinase PF00069.20 KFM03972.1 - 1.2e-72 244.2 0.1 1.5e-72 243.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM03972.1 - 1e-36 126.3 0.0 1.3e-36 125.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KFM03972.1 - 1.3e-05 24.6 0.2 2.2e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KFM03972.1 - 8.3e-05 21.7 0.1 0.00017 20.6 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Glycos_trans_3N PF02885.12 KFM03972.1 - 0.045 13.3 0.3 0.14 11.7 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain Choline_kinase PF01633.15 KFM03972.1 - 0.078 12.5 0.6 0.17 11.4 0.4 1.7 1 1 0 1 1 1 0 Choline/ethanolamine kinase RabGAP-TBC PF00566.13 KFM03973.1 - 7.5e-56 188.9 3.8 1.8e-55 187.7 2.7 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain KRAB PF01352.22 KFM03973.1 - 0.0033 16.8 0.1 0.024 14.0 0.0 2.5 2 0 0 2 2 2 1 KRAB box DUF1664 PF07889.7 KFM03973.1 - 0.047 13.4 12.2 0.17 11.6 0.6 3.4 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) Reo_sigmaC PF04582.7 KFM03973.1 - 0.52 9.4 6.6 0.077 12.1 1.5 1.7 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DivIC PF04977.10 KFM03973.1 - 2.6 7.5 26.1 0.44 10.0 3.9 4.3 3 1 1 4 4 4 0 Septum formation initiator TMF_DNA_bd PF12329.3 KFM03973.1 - 4.5 7.1 41.7 0.053 13.3 7.6 5.0 4 1 0 4 4 4 0 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.7 KFM03973.1 - 6.2 6.5 37.9 0.57 9.9 11.6 3.5 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein EF-hand_7 PF13499.1 KFM03974.1 - 1.9e-12 47.1 1.9 1.2e-10 41.3 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KFM03974.1 - 3.1e-09 35.4 7.6 0.00011 21.2 0.4 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 KFM03974.1 - 3e-06 26.6 5.8 0.025 14.4 0.3 3.7 2 1 1 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 KFM03974.1 - 5.8e-06 25.4 6.9 0.0088 15.3 0.5 3.7 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 KFM03974.1 - 0.00023 20.7 8.3 0.013 15.0 2.1 2.9 2 1 0 2 2 2 2 EF-hand domain pair PMBR PF09373.5 KFM03974.1 - 0.015 15.2 0.0 5.4 7.1 0.0 3.3 3 0 0 3 3 3 0 Pseudomurein-binding repeat AMP-binding PF00501.23 KFM03975.1 - 6e-85 285.1 0.0 7.2e-85 284.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme CTDII PF01556.13 KFM03976.1 - 2.2e-22 78.7 0.7 1.6e-17 63.1 0.0 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KFM03976.1 - 1.1e-13 51.0 18.2 2e-13 50.2 12.6 1.4 1 0 0 1 1 1 1 DnaJ central domain DnaJ PF00226.26 KFM03976.1 - 4.1e-05 23.2 0.1 7.1e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain HypA PF01155.14 KFM03976.1 - 0.091 12.4 10.3 0.97 9.1 0.5 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF2614 PF11023.3 KFM03976.1 - 3.2 7.5 5.9 3.3 7.5 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) WD40 PF00400.27 KFM03977.1 - 9.3e-59 193.3 20.4 1.3e-11 43.8 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KFM03977.1 - 1e-09 38.4 0.0 6.7e-06 25.9 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 KFM03977.1 - 2e-06 26.3 1.9 0.21 9.8 0.0 3.6 1 1 3 4 4 4 4 Cytochrome D1 heme domain Nup160 PF11715.3 KFM03977.1 - 6.5e-05 21.2 2.7 0.046 11.8 0.1 2.8 2 1 1 3 3 3 2 Nucleoporin Nup120/160 GSDH PF07995.6 KFM03977.1 - 0.00089 18.4 0.0 0.24 10.4 0.0 2.6 1 1 0 2 2 2 2 Glucose / Sorbosone dehydrogenase PD40 PF07676.7 KFM03977.1 - 0.0019 17.7 0.2 2.4 7.9 0.0 3.5 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat PQQ PF01011.16 KFM03977.1 - 0.016 14.7 2.4 13 5.5 0.0 3.9 4 0 0 4 4 4 0 PQQ enzyme repeat DUF2415 PF10313.4 KFM03977.1 - 0.021 14.4 0.0 0.17 11.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) Nucleoporin_N PF08801.6 KFM03977.1 - 0.03 13.0 2.3 0.59 8.8 0.0 3.0 1 1 1 3 3 3 0 Nup133 N terminal like DUF3312 PF11768.3 KFM03977.1 - 0.08 11.1 0.0 0.17 10.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Lipocalin PF00061.18 KFM03978.1 - 1.3e-15 57.6 0.4 1.5e-15 57.3 0.3 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Aconitase PF00330.15 KFM03979.1 - 1.1e-116 390.0 0.0 1.4e-116 389.7 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KFM03979.1 - 3.9e-38 130.5 0.0 6.6e-38 129.7 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain APH PF01636.18 KFM03980.1 - 4e-21 75.8 0.0 5.4e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KFM03980.1 - 0.063 12.3 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.15 KFM03980.1 - 0.089 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Proteasome PF00227.21 KFM03981.1 - 3.7e-56 189.4 0.0 4.8e-56 189.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KFM03981.1 - 1.1e-14 53.3 0.2 1.8e-14 52.7 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Phenol_monoox PF04663.7 KFM03981.1 - 0.062 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Phenol hydroxylase conserved region Neur_chan_LBD PF02931.18 KFM03982.1 - 3.1e-70 235.6 0.4 4.1e-70 235.3 0.3 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFM03982.1 - 1.5e-59 201.7 11.6 2.8e-47 161.5 5.0 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_memb PF02932.11 KFM03983.1 - 4.7e-80 268.8 14.1 2.6e-78 263.1 9.8 2.1 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 KFM03983.1 - 6.4e-73 244.4 1.4 1e-72 243.8 1.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFM03984.1 - 8.7e-83 277.8 1.8 1.1e-82 277.4 1.3 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 KFM03984.1 - 2.9e-70 235.7 2.0 4.9e-70 235.0 1.4 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF2417 PF10329.4 KFM03984.1 - 0.0043 16.5 0.9 0.0043 16.5 0.6 2.1 3 0 0 3 3 3 1 Region of unknown function (DUF2417) C1-set PF07654.10 KFM03985.1 - 0.00014 21.7 0.2 0.00073 19.4 0.0 2.1 2 1 0 2 2 2 1 Immunoglobulin C1-set domain RAMP PF04901.8 KFM03986.1 - 3.4e-45 152.4 2.3 3.9e-45 152.2 1.6 1.0 1 0 0 1 1 1 1 Receptor activity modifying family RVT_1 PF00078.22 KFM03987.1 - 3.2e-13 49.5 0.0 4.1e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Histone PF00125.19 KFM03989.1 - 3.3e-11 43.1 0.2 4.6e-11 42.6 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFM03989.1 - 0.00032 20.6 0.1 0.00055 19.9 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 KFM03989.1 - 0.0004 20.4 0.1 0.00067 19.7 0.1 1.5 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 KFM03989.1 - 0.00078 19.3 0.1 0.0014 18.5 0.1 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.8 KFM03989.1 - 0.016 14.9 0.2 0.026 14.2 0.1 1.3 1 0 0 1 1 1 0 Bromodomain associated RRM_1 PF00076.17 KFM03990.1 - 2.5e-80 264.1 9.9 6e-19 67.4 0.0 6.4 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM03990.1 - 6.8e-76 250.2 2.8 2.4e-17 62.6 0.0 6.4 6 0 0 6 6 6 6 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM03990.1 - 4.3e-43 144.9 1.0 6.4e-10 38.7 0.0 6.4 6 0 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFM03990.1 - 7.2e-07 29.0 10.1 0.078 12.8 0.1 6.6 4 2 2 7 7 7 3 RNA binding motif Limkain-b1 PF11608.3 KFM03990.1 - 9.7e-05 22.0 0.1 0.25 11.1 0.0 4.8 4 1 0 4 4 4 1 Limkain b1 Nup35_RRM_2 PF14605.1 KFM03990.1 - 0.0015 18.2 0.1 41 4.0 0.0 4.8 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif T-box PF00907.17 KFM03991.1 - 6e-83 276.8 0.7 1e-82 276.0 0.5 1.4 1 0 0 1 1 1 1 T-box TBX PF12598.3 KFM03991.1 - 3.1e-15 56.3 3.2 3.1e-15 56.3 2.2 1.8 2 0 0 2 2 2 1 T-box transcription factor Med13_C PF06333.7 KFM03992.1 - 4.1e-135 450.6 0.1 4.1e-135 450.6 0.1 3.6 4 0 0 4 4 4 2 Mediator complex subunit 13 C-terminal Med13_N PF11597.3 KFM03992.1 - 6.5e-106 354.3 1.1 1.3e-105 353.4 0.0 1.9 2 0 0 2 2 2 1 Mediator complex subunit 13 N-terminal WD40 PF00400.27 KFM03993.1 - 4.4e-08 32.7 10.6 0.014 15.2 0.1 5.8 7 0 0 7 7 7 3 WD domain, G-beta repeat F-box-like PF12937.2 KFM03993.1 - 3e-06 26.8 0.0 0.00013 21.6 0.0 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KFM03993.1 - 0.0043 16.6 0.0 0.0099 15.5 0.0 1.6 1 0 0 1 1 1 1 F-box domain BBS2_Mid PF14783.1 KFM03993.1 - 0.025 14.3 0.0 0.57 9.9 0.0 2.4 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region EF-hand_1 PF00036.27 KFM03994.1 - 2.9e-08 32.4 0.2 2.5e-06 26.3 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 KFM03994.1 - 6.2e-06 25.6 0.5 5e-05 22.8 0.0 2.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.1 KFM03994.1 - 1.1e-05 25.5 5.8 1.3e-05 25.2 1.9 2.3 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 KFM03994.1 - 0.0001 21.8 2.1 0.0034 16.9 0.4 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 KFM03994.1 - 0.00013 21.1 0.1 0.00042 19.5 0.0 1.9 2 0 0 2 2 2 1 EF hand Transglut_core2 PF13369.1 KFM03995.1 - 1.9e-41 141.0 0.0 3.3e-41 140.3 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily YccV-like PF08755.6 KFM03995.1 - 2.4e-28 98.0 0.2 7.5e-28 96.4 0.0 2.0 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like TPR_16 PF13432.1 KFM03995.1 - 0.012 16.2 0.0 0.023 15.3 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat NO_synthase PF02898.10 KFM03996.1 - 2.9e-222 737.0 0.1 4.2e-222 736.5 0.1 1.2 1 0 0 1 1 1 1 Nitric oxide synthase, oxygenase domain FAD_binding_1 PF00667.15 KFM03996.1 - 1.3e-78 263.4 0.0 2.7e-78 262.3 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KFM03996.1 - 2.4e-32 111.8 0.0 1.5e-31 109.3 0.0 2.4 2 1 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 KFM03996.1 - 1.4e-21 77.0 0.0 9.4e-21 74.4 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain PDZ PF00595.19 KFM03996.1 - 9.2e-17 61.0 0.0 1.9e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM03996.1 - 0.0003 20.6 0.0 0.00068 19.4 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Pkinase_Tyr PF07714.12 KFM03997.1 - 1.4e-48 165.2 0.0 1.8e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM03997.1 - 7.2e-44 149.8 0.0 1e-43 149.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain C1_1 PF00130.17 KFM03997.1 - 2.6e-05 23.8 12.1 5.5e-05 22.8 8.4 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.1 KFM03997.1 - 0.00074 18.5 0.0 0.0015 17.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFM03997.1 - 0.021 13.8 0.0 0.045 12.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFM03997.1 - 0.027 13.8 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 KFM03997.1 - 0.087 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family YccV-like PF08755.6 KFM03998.1 - 3.6e-19 68.5 0.1 7.1e-19 67.5 0.0 1.4 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like DUF4542 PF15075.1 KFM03998.1 - 0.08 12.8 0.1 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4542) WD40 PF00400.27 KFM03999.1 - 2.4e-47 157.1 18.5 8.6e-08 31.7 0.0 8.7 8 0 0 8 8 8 7 WD domain, G-beta repeat Bromodomain PF00439.20 KFM03999.1 - 1.6e-36 124.0 0.1 9.2e-17 60.7 0.0 2.8 2 0 0 2 2 2 2 Bromodomain HMG14_17 PF01101.13 KFM04000.1 - 5.8e-23 81.3 22.1 6.5e-23 81.2 15.3 1.0 1 0 0 1 1 1 1 HMG14 and HMG17 TT_ORF2 PF02957.10 KFM04000.1 - 0.1 13.2 9.9 0.12 13.0 6.9 1.0 1 0 0 1 1 1 0 TT viral ORF2 DUF2477 PF10631.4 KFM04000.1 - 0.49 10.6 2.8 0.52 10.5 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) Lebercilin PF15619.1 KFM04001.1 - 3.7e-71 238.5 50.7 3.7e-71 238.5 35.1 2.3 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease FUSC PF04632.7 KFM04001.1 - 3.9 5.7 9.3 5.5 5.2 6.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Shisa PF13908.1 KFM04002.1 - 0.1 12.8 3.4 0.038 14.1 0.6 1.7 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator SP_C-Propep PF08999.5 KFM04002.1 - 0.67 9.4 4.1 2.2 7.8 2.8 1.8 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide PEPCK PF00821.13 KFM04003.1 - 4.9e-280 929.7 0.0 5.6e-280 929.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase zf-H2C2_2 PF13465.1 KFM04004.1 - 4.8e-42 140.2 59.6 9.7e-08 31.9 0.2 8.2 8 0 0 8 8 8 7 Zinc-finger double domain zf-C2H2 PF00096.21 KFM04004.1 - 2.4e-20 71.5 69.3 0.00016 21.8 0.8 9.1 9 0 0 9 9 9 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM04004.1 - 1.1e-13 50.4 60.5 0.0043 17.2 0.1 9.0 9 0 0 9 9 9 7 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KFM04004.1 - 3.4e-08 33.2 10.3 0.00092 19.3 0.4 9.9 9 2 0 9 9 7 3 C2H2-type zinc-finger domain zf-Di19 PF05605.7 KFM04004.1 - 1.6e-05 24.8 41.4 0.063 13.3 2.1 5.3 3 1 1 5 5 5 5 Drought induced 19 protein (Di19), zinc-binding AKAP95 PF04988.7 KFM04004.1 - 0.0087 15.8 0.5 0.0087 15.8 0.3 4.2 3 2 1 4 4 3 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_6 PF13912.1 KFM04004.1 - 0.011 15.6 1.7 0.011 15.6 1.2 8.0 8 0 0 8 8 8 0 C2H2-type zinc finger zf-met PF12874.2 KFM04004.1 - 0.028 14.6 0.5 0.028 14.6 0.4 7.1 7 1 0 7 7 7 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KFM04004.1 - 0.031 14.3 37.4 1.1 9.3 9.0 5.5 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) Zn_Tnp_IS1595 PF12760.2 KFM04004.1 - 0.04 13.7 33.8 1.2 9.0 1.9 5.5 4 1 1 5 5 5 0 Transposase zinc-ribbon domain Pox_A3L PF05288.6 KFM04004.1 - 0.13 11.9 7.7 2 8.1 0.2 4.6 5 0 0 5 5 4 0 Poxvirus A3L Protein GAGA PF09237.6 KFM04004.1 - 0.18 11.4 10.6 6.1 6.5 0.0 5.0 1 1 5 6 6 6 0 GAGA factor C1_3 PF07649.7 KFM04004.1 - 0.61 10.1 0.2 0.61 10.1 0.1 7.2 8 0 0 8 8 8 0 C1-like domain Elf1 PF05129.8 KFM04004.1 - 1.2 8.9 30.3 0.13 11.9 1.1 5.3 1 1 5 6 6 6 0 Transcription elongation factor Elf1 like zf-C2H2_jaz PF12171.3 KFM04004.1 - 2.5 8.3 50.7 0.32 11.1 1.4 8.2 9 0 0 9 9 9 0 Zinc-finger double-stranded RNA-binding zf-RING_3 PF14369.1 KFM04004.1 - 5 7.1 19.9 7.1 6.7 0.1 5.6 5 1 0 5 5 5 0 zinc-finger zinc_ribbon_5 PF13719.1 KFM04004.1 - 5.1 6.7 20.7 23 4.6 0.1 6.3 7 0 0 7 7 7 0 zinc-ribbon domain WD40 PF00400.27 KFM04006.1 - 7.5e-24 82.6 15.2 8e-07 28.7 0.1 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 KFM04006.1 - 0.054 11.6 0.4 0.33 9.0 0.3 2.0 1 1 0 1 1 1 0 Nucleoporin Nup120/160 TP6A_N PF04406.9 KFM04007.1 - 2.5e-22 78.2 0.0 4.7e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase TGFb_propeptide PF00688.13 KFM04008.1 - 3.1e-56 190.3 0.0 4.6e-56 189.7 0.0 1.3 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.15 KFM04008.1 - 5.7e-44 148.6 1.3 1.2e-43 147.6 0.9 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain TF_AP-2 PF03299.9 KFM04009.1 - 6.4e-97 323.1 0.0 7.8e-97 322.8 0.0 1.1 1 0 0 1 1 1 1 Transcription factor AP-2 Rtf2 PF04641.7 KFM04010.1 - 9.7e-82 274.0 12.1 1.3e-81 273.6 8.4 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_UBOX PF13445.1 KFM04010.1 - 0.094 12.4 1.8 0.43 10.3 1.2 2.3 1 0 0 1 1 1 0 RING-type zinc-finger Branch PF02485.16 KFM04011.1 - 2.1e-52 177.7 1.3 2.2e-52 177.6 0.2 1.5 2 0 0 2 2 2 1 Core-2/I-Branching enzyme WD40 PF00400.27 KFM04012.1 - 1.3e-37 126.3 9.2 2.4e-10 39.8 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat DUF3312 PF11768.3 KFM04012.1 - 2.7e-05 22.6 0.1 0.00016 20.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3312) Pkinase PF00069.20 KFM04013.1 - 3e-70 236.3 0.0 5.2e-70 235.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM04013.1 - 7.6e-42 143.1 0.0 1.1e-41 142.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM04013.1 - 1.8e-06 27.1 0.0 7.4e-06 25.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KFM04013.1 - 0.012 15.3 0.0 0.055 13.1 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KFM04013.1 - 0.019 14.2 0.0 0.019 14.2 0.0 1.8 2 1 0 2 2 2 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.6 KFM04013.1 - 0.026 13.3 0.0 0.043 12.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 KFM04013.1 - 0.08 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1279 PF06916.8 KFM04014.1 - 1.1e-28 99.3 1.1 1.3e-28 99.0 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) YiaAB PF05360.9 KFM04014.1 - 4.6 6.8 6.0 0.79 9.3 1.1 1.9 2 1 0 2 2 2 0 yiaA/B two helix domain 7tm_1 PF00001.16 KFM04015.1 - 2.6e-41 141.4 37.6 1.1e-39 136.1 26.1 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM04015.1 - 6.3e-06 25.5 38.5 1.4e-05 24.3 26.7 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM04015.1 - 5.9 5.9 42.7 0.052 12.6 18.1 2.7 1 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Homoserine_dh PF00742.14 KFM04016.1 - 0.12 12.0 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase Apc9 PF12856.2 KFM04016.1 - 0.15 12.1 0.6 0.27 11.3 0.4 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 9 C1q PF00386.16 KFM04017.1 - 8.3e-20 71.0 0.3 9.1e-20 70.9 0.2 1.0 1 0 0 1 1 1 1 C1q domain Glyco_hydro_71 PF03659.9 KFM04017.1 - 0.038 12.4 0.0 0.039 12.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 71 IRS PF02174.12 KFM04018.1 - 1.4e-28 98.3 0.0 2.2e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 PTB domain (IRS-1 type) PH PF00169.24 KFM04018.1 - 0.034 14.3 0.1 0.069 13.3 0.1 1.4 1 0 0 1 1 1 0 PH domain Prefoldin_2 PF01920.15 KFM04019.1 - 7.9e-25 86.6 9.3 9.1e-25 86.4 6.4 1.0 1 0 0 1 1 1 1 Prefoldin subunit TPR_MLP1_2 PF07926.7 KFM04019.1 - 0.00025 20.7 3.3 0.00039 20.1 2.3 1.3 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein NPV_P10 PF05531.7 KFM04019.1 - 0.00043 20.4 6.2 0.0069 16.6 0.6 2.2 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein RraB PF06877.6 KFM04019.1 - 0.001 19.7 1.8 0.014 16.0 0.1 2.3 1 1 1 2 2 2 1 Regulator of ribonuclease activity B DivIVA PF05103.8 KFM04019.1 - 0.0012 18.8 2.9 0.0019 18.2 2.0 1.3 1 0 0 1 1 1 1 DivIVA protein Prefoldin PF02996.12 KFM04019.1 - 0.0023 17.5 8.9 0.14 11.8 6.2 2.1 1 1 0 1 1 1 1 Prefoldin subunit FlxA PF14282.1 KFM04019.1 - 0.0031 17.4 6.9 0.45 10.4 0.3 2.2 2 0 0 2 2 2 2 FlxA-like protein Med30 PF11315.3 KFM04019.1 - 0.0043 17.1 2.8 0.0054 16.8 1.9 1.1 1 0 0 1 1 1 1 Mediator complex subunit 30 FliD_C PF07195.7 KFM04019.1 - 0.0048 16.2 2.7 0.012 14.8 0.1 2.0 2 0 0 2 2 2 1 Flagellar hook-associated protein 2 C-terminus Cep57_CLD_2 PF14197.1 KFM04019.1 - 0.0099 15.7 7.8 0.6 10.0 0.4 2.3 2 0 0 2 2 2 2 Centrosome localisation domain of PPC89 Fib_alpha PF08702.5 KFM04019.1 - 0.011 15.9 5.6 1.1 9.3 0.5 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4140 PF13600.1 KFM04019.1 - 0.011 16.1 2.4 0.68 10.4 0.1 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Lzipper-MIP1 PF14389.1 KFM04019.1 - 0.018 15.1 6.0 0.1 12.7 1.1 2.1 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 TBCA PF02970.11 KFM04019.1 - 0.019 15.0 7.0 0.057 13.5 0.6 2.2 2 0 0 2 2 2 0 Tubulin binding cofactor A CCDC-167 PF15188.1 KFM04019.1 - 0.02 14.8 4.7 0.061 13.2 0.5 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 IncA PF04156.9 KFM04019.1 - 0.027 14.0 8.9 0.14 11.6 1.4 2.0 2 0 0 2 2 2 0 IncA protein FTA4 PF13093.1 KFM04019.1 - 0.028 13.8 2.6 0.04 13.3 1.8 1.3 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Med9 PF07544.8 KFM04019.1 - 0.032 13.9 14.1 0.66 9.7 2.7 3.0 2 2 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Seryl_tRNA_N PF02403.17 KFM04019.1 - 0.034 14.1 6.3 0.82 9.7 0.6 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.10 KFM04019.1 - 0.035 13.5 6.4 1.4 8.4 0.3 2.3 2 0 0 2 2 2 0 Septum formation initiator Kinesin-relat_1 PF12711.2 KFM04019.1 - 0.035 14.4 6.8 0.05 13.9 0.9 2.2 2 0 0 2 2 2 0 Kinesin motor DUF1664 PF07889.7 KFM04019.1 - 0.043 13.6 5.6 0.074 12.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Mod_r PF07200.8 KFM04019.1 - 0.044 13.7 5.8 1.5 8.6 0.6 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein GP41 PF00517.12 KFM04019.1 - 0.044 13.3 4.3 0.33 10.5 0.2 2.0 2 0 0 2 2 2 0 Retroviral envelope protein FlgN PF05130.7 KFM04019.1 - 0.057 13.6 2.8 0.077 13.2 1.9 1.1 1 0 0 1 1 1 0 FlgN protein Atg14 PF10186.4 KFM04019.1 - 0.062 12.2 5.9 1.2 8.0 0.3 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Mnd1 PF03962.10 KFM04019.1 - 0.063 12.9 4.8 0.12 12.0 3.3 1.5 1 1 0 1 1 1 0 Mnd1 family Acyl-CoA_dh_C PF12806.2 KFM04019.1 - 0.074 12.9 0.5 6 6.7 0.1 2.0 2 0 0 2 2 2 0 Acetyl-CoA dehydrogenase C-terminal like KxDL PF10241.4 KFM04019.1 - 0.075 12.9 1.7 4.3 7.3 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein Glyco_hydro_4C PF11975.3 KFM04019.1 - 0.094 12.4 0.5 0.14 11.9 0.3 1.3 1 1 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain GvpL_GvpF PF06386.6 KFM04019.1 - 0.097 12.2 1.4 0.38 10.3 0.4 1.7 1 1 1 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF AATF-Che1 PF13339.1 KFM04019.1 - 0.1 12.7 3.3 0.36 10.9 0.4 2.0 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor TMF_DNA_bd PF12329.3 KFM04019.1 - 0.12 12.2 13.1 1.1 9.1 0.9 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TBPIP PF07106.8 KFM04019.1 - 0.12 11.9 6.8 1.1 8.7 0.6 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) AAA_23 PF13476.1 KFM04019.1 - 0.12 12.6 6.4 0.16 12.2 4.5 1.2 1 0 0 1 1 1 0 AAA domain Tropomyosin_1 PF12718.2 KFM04019.1 - 0.12 12.1 12.2 0.27 11.0 3.0 2.1 2 0 0 2 2 2 0 Tropomyosin like DUF4200 PF13863.1 KFM04019.1 - 0.13 12.1 10.3 1.5 8.7 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Syntaxin PF00804.20 KFM04019.1 - 0.16 12.1 4.2 0.25 11.5 2.9 1.3 1 0 0 1 1 1 0 Syntaxin Occludin_ELL PF07303.8 KFM04019.1 - 0.17 12.6 2.7 6.1 7.6 0.1 2.1 2 0 0 2 2 2 0 Occludin homology domain GAS PF13851.1 KFM04019.1 - 0.18 10.9 9.4 1.1 8.3 1.3 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Syntaxin-6_N PF09177.6 KFM04019.1 - 0.22 11.9 3.8 2.2 8.7 0.2 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal ATG16 PF08614.6 KFM04019.1 - 0.29 10.9 10.8 0.54 10.0 1.1 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) ADIP PF11559.3 KFM04019.1 - 0.3 11.0 7.6 0.69 9.8 0.9 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Ax_dynein_light PF10211.4 KFM04019.1 - 0.32 10.8 8.1 0.95 9.2 0.9 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain Sec2p PF06428.6 KFM04019.1 - 0.33 10.8 7.2 1.6 8.6 1.0 2.1 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p RNA_pol_Rpb1_5 PF04998.12 KFM04019.1 - 0.35 10.0 1.8 0.4 9.8 1.2 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Fmp27_WPPW PF10359.4 KFM04019.1 - 0.36 9.1 5.7 0.89 7.9 4.0 1.6 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF713 PF05218.9 KFM04019.1 - 0.46 10.1 5.9 0.93 9.1 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF713) DUF1732 PF08340.6 KFM04019.1 - 0.5 10.2 5.7 6.9 6.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1732) Bap31 PF05529.7 KFM04019.1 - 0.52 9.7 7.1 2.6 7.4 0.5 2.0 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like XhlA PF10779.4 KFM04019.1 - 0.54 10.2 7.0 1.6 8.7 0.3 2.3 2 0 0 2 2 2 0 Haemolysin XhlA GrpE PF01025.14 KFM04019.1 - 0.56 9.7 5.9 2.9 7.4 0.5 2.0 2 0 0 2 2 2 0 GrpE CtIP_N PF10482.4 KFM04019.1 - 0.58 9.9 6.1 1.5 8.6 0.4 2.2 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain DUF342 PF03961.8 KFM04019.1 - 0.63 8.3 6.2 0.95 7.7 4.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Spc24 PF08286.6 KFM04019.1 - 0.65 9.7 10.3 3.1 7.5 1.5 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 OmpH PF03938.9 KFM04019.1 - 0.66 9.8 5.7 1.2 9.0 3.9 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3450 PF11932.3 KFM04019.1 - 0.68 9.1 6.1 1.5 7.9 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.4 KFM04019.1 - 0.75 9.6 11.6 0.69 9.7 2.5 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF972 PF06156.8 KFM04019.1 - 1 9.7 7.0 0.65 10.3 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Phage_GPO PF05929.6 KFM04019.1 - 1.1 8.4 4.0 5 6.2 0.2 2.0 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase IATP PF04568.7 KFM04019.1 - 1.4 8.9 8.3 4.2 7.4 0.4 2.2 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP PCRF PF03462.13 KFM04019.1 - 1.5 8.5 4.8 2.4 7.9 0.3 2.1 2 0 0 2 2 2 0 PCRF domain SlyX PF04102.7 KFM04019.1 - 1.6 9.1 5.6 15 6.0 0.7 2.4 2 0 0 2 2 2 0 SlyX UPF0449 PF15136.1 KFM04019.1 - 2.3 8.5 5.3 8.7 6.6 0.5 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Med4 PF10018.4 KFM04019.1 - 2.6 7.4 8.9 3 7.1 0.9 2.1 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF2681 PF10883.3 KFM04019.1 - 3.6 7.8 7.3 7.1 6.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Uds1 PF15456.1 KFM04019.1 - 4.9 7.1 8.3 1e+02 2.9 5.7 2.2 1 1 0 1 1 1 0 Up-regulated During Septation FlaC_arch PF05377.6 KFM04019.1 - 8.2 6.4 9.6 7.4 6.5 0.7 2.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Fzo_mitofusin PF04799.8 KFM04019.1 - 10 5.4 9.0 3.6 6.9 1.2 2.0 1 1 0 2 2 2 0 fzo-like conserved region p450 PF00067.17 KFM04020.1 - 2.4e-85 286.8 0.3 2.6e-85 286.6 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-C2H2 PF00096.21 KFM04022.1 - 2.7e-19 68.2 54.8 6.4e-05 23.0 0.7 9.5 10 0 0 10 10 10 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM04022.1 - 4.3e-12 45.4 54.7 0.03 14.6 1.0 9.0 9 0 0 9 9 9 7 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFM04022.1 - 1e-09 38.1 62.8 3.9e-08 33.1 0.2 11.5 13 0 0 13 13 13 6 Zinc-finger double domain zf-C2H2_2 PF12756.2 KFM04022.1 - 2e-05 24.5 30.7 0.00044 20.3 1.6 7.0 4 2 1 6 6 6 3 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.1 KFM04022.1 - 0.0077 16.4 49.5 0.27 11.5 2.4 8.7 8 0 0 8 8 8 3 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 KFM04022.1 - 0.027 14.6 28.5 0.16 12.1 0.1 6.3 5 1 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 KFM04022.1 - 0.51 10.0 13.7 0.93 9.2 0.6 5.3 5 0 0 5 5 5 0 zinc-finger of a C2HC-type GATA PF00320.22 KFM04022.1 - 2.3 7.6 8.3 11 5.4 0.3 3.9 3 0 0 3 3 3 0 GATA zinc finger zf-C2H2_2 PF12756.2 KFM04024.1 - 7.4e-08 32.4 24.9 0.0038 17.2 0.2 4.6 3 1 1 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 KFM04024.1 - 0.00031 20.8 21.7 0.28 11.6 0.5 5.6 5 1 0 5 5 5 3 C2H2-type zinc finger zf-met PF12874.2 KFM04024.1 - 0.00046 20.2 10.5 0.12 12.6 0.3 3.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFM04024.1 - 0.058 13.5 0.3 0.058 13.5 0.2 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 KFM04024.1 - 0.13 12.6 32.3 0.14 12.5 0.6 5.8 6 0 0 6 6 6 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KFM04024.1 - 0.14 12.1 19.6 0.67 9.9 0.1 4.8 4 0 0 4 4 4 0 C2H2-type zinc finger DUF678 PF05077.7 KFM04024.1 - 0.49 10.4 9.8 0.99 9.4 0.1 3.8 5 0 0 5 5 5 0 Protein of unknown function (DUF678) Hydrolase PF00702.21 KFM04025.1 - 1.1e-18 68.4 0.0 2.9e-18 67.0 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KFM04025.1 - 1.4e-18 66.7 0.1 3.8e-18 65.3 0.1 1.7 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 KFM04025.1 - 7.1e-13 49.1 0.2 2e-12 47.6 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFM04025.1 - 1.1e-05 25.2 0.0 4.3e-05 23.3 0.0 2.0 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFM04025.1 - 0.0031 17.1 0.0 0.012 15.1 0.0 2.0 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase GNVR PF13807.1 KFM04025.1 - 0.059 13.1 0.1 0.23 11.2 0.1 2.0 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase RHD PF00554.17 KFM04026.1 - 1.5e-22 80.0 0.5 4.7e-22 78.5 0.4 1.8 1 1 0 1 1 1 1 Rel homology domain (RHD) TIG PF01833.19 KFM04026.1 - 5.2e-06 26.3 0.0 2.9e-05 23.9 0.0 2.4 1 0 0 1 1 1 1 IPT/TIG domain Ion_trans PF00520.26 KFM04027.1 - 8.6e-29 100.2 5.8 5e-28 97.7 4.8 1.6 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 KFM04027.1 - 3.2e-27 94.5 0.0 7e-27 93.4 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.11 KFM04027.1 - 8.1e-14 51.0 3.2 8.1e-14 51.0 2.2 2.0 2 0 0 2 2 2 1 Ion channel ThiF PF00899.16 KFM04028.1 - 8.9e-41 138.9 0.0 1.4e-40 138.2 0.0 1.3 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 KFM04028.1 - 6.8e-32 108.9 0.1 1.3e-31 108.0 0.1 1.5 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 KFM04028.1 - 5.5e-11 42.8 0.0 1.3e-10 41.5 0.0 1.7 2 0 0 2 2 2 1 Rhodanese-like domain adh_short PF00106.20 KFM04028.1 - 0.07 13.0 0.6 0.17 11.8 0.4 1.7 1 1 0 1 1 1 0 short chain dehydrogenase Glycos_transf_2 PF00535.21 KFM04029.1 - 3.7e-33 114.5 0.0 4.4e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KFM04029.1 - 3.6e-10 40.0 0.0 2.2e-09 37.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 KFM04029.1 - 1.1e-07 31.2 0.0 1.5e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KFM04029.1 - 1.7e-05 24.2 0.0 2.4e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.1 KFM04029.1 - 0.041 14.1 0.0 0.079 13.2 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferase family 2 Homeobox PF00046.24 KFM04030.1 - 1.3e-07 31.0 0.2 4.8e-07 29.2 0.3 1.8 2 0 0 2 2 2 1 Homeobox domain zf-H2C2_5 PF13909.1 KFM04030.1 - 9.2e-05 22.4 0.5 9.2e-05 22.4 0.3 7.1 8 0 0 8 8 8 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 KFM04030.1 - 0.00019 21.5 45.1 0.021 15.1 0.1 8.7 8 0 0 8 8 8 3 C2H2-type zinc finger Homeobox_KN PF05920.6 KFM04030.1 - 0.0089 15.7 0.3 0.024 14.3 0.2 1.8 1 0 0 1 1 1 1 Homeobox KN domain zf-C2H2 PF00096.21 KFM04030.1 - 0.082 13.2 0.3 0.082 13.2 0.2 7.3 8 0 0 8 8 8 0 Zinc finger, C2H2 type zf-Di19 PF05605.7 KFM04030.1 - 0.11 12.6 0.2 0.11 12.6 0.1 7.3 7 2 1 8 8 8 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 KFM04030.1 - 4 7.7 9.8 13 6.0 0.0 4.6 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFM04030.1 - 6.8 6.8 32.1 0.068 13.2 4.5 6.8 4 3 2 6 6 6 0 C2H2 type zinc-finger (2 copies) PB1 PF00564.19 KFM04031.1 - 8.3e-13 47.8 0.0 1.5e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 PB1 domain PDZ PF00595.19 KFM04031.1 - 1.8e-11 44.0 0.0 3.4e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM04031.1 - 0.036 13.9 0.0 0.081 12.8 0.0 1.6 1 0 0 1 1 1 0 PDZ domain Y_phosphatase PF00102.22 KFM04032.1 - 8e-81 270.8 0.0 1e-80 270.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFM04032.1 - 6.4e-05 22.5 0.0 0.00011 21.7 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFM04032.1 - 0.032 14.4 0.5 0.14 12.4 0.1 2.0 2 1 0 2 2 2 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KFM04032.1 - 0.037 14.0 0.2 0.14 12.1 0.1 2.2 1 1 0 1 1 1 0 Inositol hexakisphosphate CDKN3 PF05706.7 KFM04032.1 - 0.13 11.7 0.0 0.27 10.6 0.0 1.6 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Kua-UEV1_localn PF10520.4 KFM04034.1 - 2.5e-31 108.6 2.5 3.6e-31 108.1 1.7 1.2 1 0 0 1 1 1 1 Kua-ubiquitin conjugating enzyme hybrid localisation domain UQ_con PF00179.21 KFM04034.1 - 1.9e-18 66.2 0.0 3e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KFM04034.1 - 0.0023 17.7 0.0 0.0037 17.1 0.0 1.4 1 0 0 1 1 1 1 RWD domain zf-C2H2 PF00096.21 KFM04035.1 - 7.3e-23 79.4 37.0 8.9e-06 25.7 0.5 5.2 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM04035.1 - 1.2e-20 72.7 28.9 3.7e-08 33.2 0.2 5.4 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFM04035.1 - 9.4e-14 51.0 21.8 0.00033 20.6 0.7 5.3 4 1 1 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KFM04035.1 - 3e-13 49.0 33.4 0.0014 18.7 0.5 5.3 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM04035.1 - 1e-09 37.9 32.4 0.00079 19.2 0.2 5.4 5 1 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.2 KFM04035.1 - 1.1e-07 31.7 18.2 0.0072 16.4 0.7 4.4 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-Di19 PF05605.7 KFM04035.1 - 0.00012 22.1 18.2 0.052 13.6 1.0 3.5 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.10 KFM04035.1 - 0.0042 16.8 31.3 0.36 10.6 1.8 5.2 2 2 3 5 5 5 3 BED zinc finger Zn-ribbon_8 PF09723.5 KFM04035.1 - 0.0077 16.1 24.1 0.59 10.1 0.5 4.8 4 1 0 4 4 4 2 Zinc ribbon domain zf-C2H2_2 PF12756.2 KFM04035.1 - 0.012 15.7 23.0 1.1 9.4 0.9 4.9 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) Rpr2 PF04032.11 KFM04035.1 - 0.015 15.1 16.2 0.032 14.0 0.6 2.5 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C2HC_2 PF13913.1 KFM04035.1 - 0.054 13.1 14.4 0.31 10.7 0.4 4.5 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-CHY PF05495.7 KFM04035.1 - 0.65 10.2 24.4 0.13 12.4 2.7 2.5 2 1 0 2 2 2 0 CHY zinc finger PyrI_C PF02748.10 KFM04035.1 - 1.1 8.7 15.7 0.65 9.4 0.7 4.3 4 1 1 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-HYPF PF07503.7 KFM04035.1 - 3.9 6.9 14.7 3.9 6.9 1.2 3.9 4 1 0 4 4 4 0 HypF finger zf-AN1 PF01428.11 KFM04035.1 - 6.6 6.6 22.7 14 5.6 0.1 5.1 5 0 0 5 5 5 0 AN1-like Zinc finger DUF2180 PF09947.4 KFM04035.1 - 7 6.4 9.1 1.2 8.8 1.8 2.6 3 1 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2180) zf-Di19 PF05605.7 KFM04036.1 - 1.2e-18 66.9 2.1 1.2e-18 66.9 1.4 3.2 2 1 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding DND1_DSRM PF14709.1 KFM04036.1 - 0.017 15.4 0.0 0.064 13.5 0.0 2.0 2 1 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 DYW_deaminase PF14432.1 KFM04036.1 - 0.042 13.8 1.2 3.5 7.6 0.0 2.6 1 1 1 2 2 2 0 DYW family of nucleic acid deaminases zf-DNA_Pol PF08996.5 KFM04036.1 - 0.059 12.7 7.8 0.29 10.4 0.1 2.1 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger Methyltransf_15 PF09445.5 KFM04036.1 - 0.067 12.7 0.0 0.083 12.4 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase zf-C2H2 PF00096.21 KFM04036.1 - 0.11 12.8 1.0 0.11 12.8 0.7 4.6 4 1 0 4 4 4 0 Zinc finger, C2H2 type zf-BED PF02892.10 KFM04036.1 - 0.18 11.5 0.1 0.18 11.5 0.1 3.5 3 1 1 4 4 4 0 BED zinc finger DZR PF12773.2 KFM04036.1 - 0.19 11.5 18.2 0.32 10.8 0.6 2.9 2 1 0 2 2 2 0 Double zinc ribbon RRN7 PF11781.3 KFM04036.1 - 0.28 10.7 7.4 2.2 7.8 0.1 3.6 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-H2C2_2 PF13465.1 KFM04036.1 - 0.4 11.0 0.1 0.4 11.0 0.1 4.5 5 0 0 5 5 5 0 Zinc-finger double domain tRNA-synt_1g PF09334.6 KFM04036.1 - 1.5 7.4 4.3 4 5.9 3.0 1.8 1 1 1 2 2 2 0 tRNA synthetases class I (M) YdjO PF14169.1 KFM04036.1 - 2 7.9 9.1 3.3 7.2 0.0 3.9 4 0 0 4 4 4 0 Cold-inducible protein YdjO zf-C4pol PF14260.1 KFM04036.1 - 9.2 6.3 15.7 0.7 9.9 5.8 2.4 2 1 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Zn_Tnp_IS1595 PF12760.2 KFM04036.1 - 9.7 6.0 13.9 21 5.0 0.1 3.8 3 1 0 3 3 3 0 Transposase zinc-ribbon domain PUB PF09409.5 KFM04037.1 - 0.02 14.6 0.0 0.045 13.4 0.0 1.6 1 0 0 1 1 1 0 PUB domain MFS_1 PF07690.11 KFM04038.1 - 1.2e-18 66.9 18.8 3.9e-12 45.5 3.5 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFM04038.1 - 9.6e-18 63.7 17.2 1.2e-12 46.9 0.5 2.8 2 1 1 3 3 3 3 MFS/sugar transport protein Inhibitor_Mig-6 PF11555.3 KFM04039.1 - 3.7e-25 88.1 11.2 3.7e-25 88.1 7.7 3.6 3 0 0 3 3 3 1 EGFR receptor inhibitor Mig-6 GTPase_binding PF09027.5 KFM04039.1 - 4.9e-22 77.3 0.0 1.1e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 GTPase binding Senescence_reg PF04520.8 KFM04039.1 - 0.097 13.1 0.9 0.26 11.7 0.7 1.8 1 0 0 1 1 1 0 Senescence regulator DJ-1_PfpI PF01965.19 KFM04040.1 - 1e-34 119.1 0.0 1.3e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 KFM04040.1 - 5.9e-16 58.1 0.0 7e-16 57.9 0.0 1.0 1 0 0 1 1 1 1 Putative amidotransferase GATase_3 PF07685.9 KFM04040.1 - 0.014 15.0 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain TNFR_c6 PF00020.13 KFM04041.1 - 1.5e-06 28.1 5.2 1.5e-06 28.1 3.6 3.5 3 0 0 3 3 3 2 TNFR/NGFR cysteine-rich region GCC2_GCC3 PF07699.8 KFM04041.1 - 7.8 6.1 28.6 0.052 13.1 3.4 3.5 1 1 2 3 3 3 0 GCC2 and GCC3 Urotensin_II PF02083.10 KFM04042.1 - 1.2e-06 27.4 1.1 2.2e-06 26.6 0.8 1.4 1 0 0 1 1 1 1 Urotensin II Period_C PF12114.3 KFM04043.1 - 2e-42 145.0 19.7 2e-42 145.0 13.6 5.0 5 1 0 5 5 5 1 Period protein 2/3C-terminal region PAS_11 PF14598.1 KFM04043.1 - 8.3e-14 51.4 0.0 1.3e-12 47.6 0.0 2.6 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.6 KFM04043.1 - 2.4e-12 46.8 0.0 1.3e-11 44.3 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS PF00989.19 KFM04043.1 - 2.6e-09 36.8 0.0 2.3e-06 27.3 0.0 2.9 2 0 0 2 2 2 2 PAS fold STE3 PF02076.10 KFM04043.1 - 0.064 12.3 0.2 0.11 11.6 0.2 1.2 1 0 0 1 1 1 0 Pheromone A receptor Synaptobrevin PF00957.16 KFM04044.1 - 9.6e-36 121.2 4.1 1.1e-35 121.1 2.9 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF247 PF03140.10 KFM04044.1 - 0.027 13.5 0.1 0.03 13.3 0.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function Fijivirus_P9-2 PF06837.6 KFM04044.1 - 0.049 12.7 0.1 0.06 12.4 0.1 1.2 1 0 0 1 1 1 0 Fijivirus P9-2 protein ERM PF00769.14 KFM04044.1 - 0.05 13.1 0.3 0.061 12.8 0.2 1.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family ODV-E18 PF10717.4 KFM04044.1 - 0.066 12.6 0.2 0.13 11.7 0.0 1.6 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 ASFV_J13L PF05568.6 KFM04044.1 - 5 6.6 7.7 6.5 6.2 5.0 1.4 1 1 0 1 1 1 0 African swine fever virus J13L protein CG-1 PF03859.11 KFM04045.1 - 7.5e-44 148.0 1.3 7.5e-44 148.0 0.9 2.1 2 0 0 2 2 2 1 CG-1 domain TIG PF01833.19 KFM04045.1 - 6e-09 35.7 2.9 6.7e-09 35.6 0.1 2.7 2 0 0 2 2 2 1 IPT/TIG domain Ank_2 PF12796.2 KFM04045.1 - 1.4e-08 34.9 0.2 0.00013 22.2 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFM04045.1 - 2.3e-06 27.6 0.4 0.15 12.3 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KFM04045.1 - 3.1e-06 26.6 1.3 0.11 12.3 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 KFM04045.1 - 8.1e-05 22.4 0.2 0.69 10.3 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat IQ PF00612.22 KFM04045.1 - 0.00089 18.7 18.9 0.19 11.4 0.3 5.4 5 0 0 5 5 5 3 IQ calmodulin-binding motif Ank_4 PF13637.1 KFM04045.1 - 0.002 18.6 0.5 0.12 12.8 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ca_chan_IQ PF08763.6 KFM04045.1 - 9.7 5.5 15.4 0.051 12.8 0.6 3.6 3 1 0 3 3 3 0 Voltage gated calcium channel IQ domain DUF3395 PF11875.3 KFM04046.1 - 1.1e-43 148.4 0.3 2.2e-43 147.4 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 KFM04046.1 - 2e-19 69.0 2.0 4e-19 68.1 0.5 2.1 2 0 0 2 2 2 1 DnaJ domain Selenoprotein_S PF06936.6 KFM04046.1 - 0.026 14.0 0.2 0.062 12.8 0.1 1.6 1 0 0 1 1 1 0 Selenoprotein S (SelS) PHD PF00628.24 KFM04047.1 - 1.4e-08 34.2 8.2 2.4e-08 33.5 5.7 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KFM04047.1 - 8.6e-06 24.9 4.8 1.5e-05 24.2 3.3 1.4 1 0 0 1 1 1 1 PHD-finger DDA1 PF10172.4 KFM04047.1 - 0.017 14.9 0.1 0.64 9.8 0.0 2.4 2 0 0 2 2 2 0 Det1 complexing ubiquitin ligase C1_1 PF00130.17 KFM04047.1 - 0.017 14.8 2.1 0.017 14.8 1.5 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) AfaD PF05775.7 KFM04047.1 - 0.082 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Enterobacteria AfaD invasin protein zf-CW PF07496.10 KFM04047.1 - 0.14 11.8 3.4 0.39 10.4 2.4 1.7 1 0 0 1 1 1 0 CW-type Zinc Finger Autophagy_N PF03986.8 KFM04047.1 - 0.2 11.4 3.1 0.2 11.3 1.5 1.6 1 1 1 2 2 2 0 Autophagocytosis associated protein (Atg3), N-terminal domain DUF3268 PF11672.3 KFM04047.1 - 1 9.4 3.8 6 6.9 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3268) Prok-RING_1 PF14446.1 KFM04047.1 - 1 9.1 6.5 0.14 11.8 1.1 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 C1_2 PF03107.11 KFM04047.1 - 1.2 9.3 5.0 19 5.4 0.1 2.4 2 0 0 2 2 2 0 C1 domain Kelch_1 PF01344.20 KFM04048.1 - 2e-38 129.6 18.0 4.8e-11 42.0 1.1 7.7 6 2 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 KFM04048.1 - 1.6e-35 119.8 5.5 3.3e-09 36.5 0.0 6.3 2 1 4 6 6 6 6 Kelch motif Kelch_3 PF13415.1 KFM04048.1 - 1.5e-21 75.9 10.0 7.1e-07 29.2 0.0 5.6 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.10 KFM04048.1 - 1.5e-18 65.7 12.4 1.5e-07 30.8 0.0 6.4 6 1 0 6 6 6 3 Kelch motif Kelch_4 PF13418.1 KFM04048.1 - 1.7e-16 59.7 12.1 5e-06 26.1 0.3 6.8 8 1 0 8 8 8 3 Galactose oxidase, central domain Kelch_5 PF13854.1 KFM04048.1 - 3.6e-05 23.5 12.5 0.072 13.0 0.2 4.4 4 1 0 4 4 4 2 Kelch motif PQQ_3 PF13570.1 KFM04048.1 - 0.0046 17.1 5.0 0.76 10.1 0.1 3.6 3 0 0 3 3 3 1 PQQ-like domain Fer4_12 PF13353.1 KFM04048.1 - 0.025 14.7 0.0 0.26 11.4 0.0 2.2 2 1 0 2 2 2 0 4Fe-4S single cluster domain DUF1668 PF07893.8 KFM04048.1 - 0.058 12.5 0.1 2.5 7.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1668) HARP PF07443.8 KFM04048.1 - 0.072 12.4 0.1 4.6 6.6 0.0 3.2 3 0 0 3 3 3 0 HepA-related protein (HARP) PFU PF09070.6 KFM04048.1 - 0.074 13.0 0.2 0.5 10.4 0.0 2.4 2 1 1 3 3 3 0 PFU (PLAA family ubiquitin binding) zf-H2C2_2 PF13465.1 KFM04049.1 - 4.8e-54 178.1 81.3 8.2e-10 38.4 1.5 11.1 11 0 0 11 11 11 10 Zinc-finger double domain zf-C2H2 PF00096.21 KFM04049.1 - 2.9e-38 127.9 85.5 1.1e-05 25.4 1.3 10.3 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM04049.1 - 2.5e-30 102.5 80.1 0.00023 21.2 1.2 10.4 10 0 0 10 10 10 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM04049.1 - 4e-10 39.5 48.3 0.004 17.2 0.4 9.8 10 0 0 10 10 10 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM04049.1 - 1.6e-09 37.6 53.3 0.04 14.1 0.7 9.6 9 0 0 9 9 9 5 Zinc-finger of C2H2 type zf-Di19 PF05605.7 KFM04049.1 - 6.1e-08 32.6 54.6 0.00043 20.3 1.2 6.4 4 2 1 6 6 6 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 KFM04049.1 - 0.0013 18.5 63.1 0.031 14.1 0.3 10.1 10 0 0 10 10 10 4 C2H2-type zinc finger GAGA PF09237.6 KFM04049.1 - 0.0016 18.0 3.9 0.025 14.1 0.2 6.0 2 2 4 7 7 7 3 GAGA factor DUF2387 PF09526.5 KFM04049.1 - 0.0061 16.4 0.4 0.0061 16.4 0.3 5.2 2 1 3 5 5 5 1 Probable metal-binding protein (DUF2387) C1_1 PF00130.17 KFM04049.1 - 0.0087 15.7 47.4 0.052 13.2 1.6 6.6 5 2 0 6 6 6 3 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-H2C2_5 PF13909.1 KFM04049.1 - 0.015 15.5 7.2 0.027 14.6 1.3 10.3 10 1 0 10 10 10 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.2 KFM04049.1 - 0.079 13.0 61.3 0.089 12.9 6.0 8.7 1 1 2 5 5 5 0 C2H2 type zinc-finger (2 copies) Elf1 PF05129.8 KFM04049.1 - 1.6 8.5 44.4 0.17 11.6 1.0 6.4 1 1 7 8 8 8 0 Transcription elongation factor Elf1 like Rpr2 PF04032.11 KFM04049.1 - 2.3 8.1 34.7 0.2 11.5 0.4 4.9 4 1 0 4 4 4 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain BolA PF01722.13 KFM04049.1 - 3.9 7.4 5.7 44 4.1 0.0 4.0 3 2 2 5 5 5 0 BolA-like protein Clp1 PF06807.9 KFM04050.1 - 3e-45 154.3 0.0 4.5e-45 153.8 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 WH2 PF02205.15 KFM04051.1 - 2.2e-06 27.0 0.1 4e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 WH2 motif VHP PF02209.14 KFM04051.1 - 0.013 15.1 2.2 0.8 9.4 0.1 2.7 2 0 0 2 2 2 0 Villin headpiece domain Phostensin_N PF13916.1 KFM04051.1 - 0.05 13.5 0.8 0.05 13.5 0.6 3.9 1 1 4 5 5 5 0 PP1-regulatory protein, Phostensin N-terminal AAA_23 PF13476.1 KFM04051.1 - 1 9.6 10.1 1.4 9.2 7.0 1.1 1 0 0 1 1 1 0 AAA domain 4HBT PF03061.17 KFM04052.1 - 1.4e-26 92.4 0.9 1.4e-14 53.9 0.1 2.3 2 0 0 2 2 2 2 Thioesterase superfamily tRNA_anti-codon PF01336.20 KFM04052.1 - 0.00012 21.8 0.0 0.0027 17.5 0.0 2.2 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain CARDB PF07705.6 KFM04052.1 - 0.052 13.5 0.2 0.65 10.0 0.0 2.2 2 0 0 2 2 2 0 CARDB ICMT PF04140.9 KFM04053.1 - 8.2e-35 118.8 0.1 1.3e-34 118.2 0.1 1.3 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 KFM04053.1 - 4e-10 39.7 0.6 6.5e-10 39.0 0.4 1.3 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.7 KFM04053.1 - 0.015 14.5 0.2 0.018 14.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) zf-B_box PF00643.19 KFM04054.1 - 9.3e-07 28.6 10.0 9.3e-07 28.6 6.9 4.2 4 0 0 4 4 3 2 B-box zinc finger zf-RING_5 PF14634.1 KFM04054.1 - 2e-05 24.2 11.8 2e-05 24.2 8.2 3.8 3 0 0 3 3 3 1 zinc-RING finger domain MAD PF05557.8 KFM04054.1 - 0.0007 17.8 0.3 0.0007 17.8 0.2 2.1 2 0 0 2 2 2 1 Mitotic checkpoint protein zf-RING_2 PF13639.1 KFM04054.1 - 0.001 18.8 12.4 0.001 18.8 8.6 3.5 3 0 0 3 3 2 1 Ring finger domain IL10 PF00726.12 KFM04054.1 - 0.0021 17.3 1.4 0.0021 17.3 0.9 2.6 2 2 0 2 2 2 1 Interleukin 10 AIP3 PF03915.8 KFM04054.1 - 0.01 14.7 9.0 0.066 12.1 0.7 2.1 2 0 0 2 2 2 0 Actin interacting protein 3 zf-CHC2 PF01807.15 KFM04054.1 - 0.029 13.9 2.0 0.043 13.3 0.2 2.2 2 0 0 2 2 2 0 CHC2 zinc finger DUF3400 PF11880.3 KFM04054.1 - 0.066 12.4 0.3 0.12 11.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3400) Exonuc_VII_L PF02601.10 KFM04054.1 - 0.19 10.8 5.1 0.058 12.5 0.4 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit Baculo_PEP_C PF04513.7 KFM04054.1 - 0.56 10.0 3.7 1.4 8.7 0.7 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FUSC PF04632.7 KFM04054.1 - 1.1 7.6 4.7 0.36 9.1 1.6 1.4 2 0 0 2 2 2 0 Fusaric acid resistance protein family OmpH PF03938.9 KFM04054.1 - 1.7 8.5 8.9 2.4 8.0 0.5 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) FliT PF05400.8 KFM04054.1 - 6.2 7.3 11.5 6.1 7.3 2.4 3.2 3 0 0 3 3 3 0 Flagellar protein FliT DivIVA PF05103.8 KFM04054.1 - 8.2 6.4 17.3 11 6.0 1.4 2.7 2 1 0 2 2 2 0 DivIVA protein Ribosomal_L22e PF01776.12 KFM04055.1 - 6.6e-54 180.6 2.4 7.7e-54 180.4 1.6 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family CHDCT2 PF08074.6 KFM04056.1 - 5.5e-91 302.9 1.7 6.5e-91 302.7 0.0 2.0 2 0 0 2 2 2 1 CHDCT2 (NUC038) domain SNF2_N PF00176.18 KFM04056.1 - 9.3e-68 228.1 0.1 9.3e-68 228.1 0.1 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain DUF1086 PF06461.6 KFM04056.1 - 1.9e-62 209.3 0.0 1.9e-62 209.3 0.0 1.9 2 0 0 2 2 1 1 Domain of Unknown Function (DUF1086) CHDNT PF08073.7 KFM04056.1 - 3.8e-30 103.3 0.4 9.9e-30 102.0 0.3 1.7 1 0 0 1 1 1 1 CHDNT (NUC034) domain DUF1087 PF06465.8 KFM04056.1 - 6.2e-26 90.1 6.6 6.2e-26 90.1 4.6 3.0 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1087) Chromo PF00385.19 KFM04056.1 - 3.4e-18 65.0 6.4 2.9e-12 46.0 0.5 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 KFM04056.1 - 1.2e-16 60.3 0.0 3.4e-16 58.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PHD PF00628.24 KFM04056.1 - 9.9e-12 44.3 6.6 2.3e-11 43.1 4.6 1.7 1 0 0 1 1 1 1 PHD-finger ResIII PF04851.10 KFM04056.1 - 3.5e-05 23.7 0.0 3.5e-05 23.7 0.0 2.8 3 0 0 3 3 1 1 Type III restriction enzyme, res subunit zf-HC5HC2H PF13771.1 KFM04056.1 - 0.0098 16.0 0.4 0.026 14.6 0.3 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain AAA_22 PF13401.1 KFM04056.1 - 0.017 15.2 0.0 0.077 13.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Prok-RING_1 PF14446.1 KFM04056.1 - 0.26 11.0 3.2 0.57 9.9 2.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Aldo_ket_red PF00248.16 KFM04057.1 - 7.4e-40 136.5 0.0 5.6e-32 110.6 0.0 2.1 2 0 0 2 2 2 2 Aldo/keto reductase family MRF_C1 PF13887.1 KFM04057.1 - 0.093 11.7 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 AJAP1_PANP_C PF15298.1 KFM04059.1 - 6.8e-41 140.4 0.9 7.7e-41 140.2 0.6 1.0 1 0 0 1 1 1 1 AJAP1/PANP C-terminus DFF40 PF09230.5 KFM04062.1 - 5.8e-102 339.9 4.8 6.7e-102 339.7 3.4 1.0 1 0 0 1 1 1 1 DNA fragmentation factor 40 kDa UVR PF02151.14 KFM04063.1 - 0.00087 18.7 14.0 0.029 13.9 2.3 2.8 2 0 0 2 2 2 2 UvrB/uvrC motif CLASP_N PF12348.3 KFM04063.1 - 0.02 14.2 0.1 0.04 13.2 0.1 1.4 1 0 0 1 1 1 0 CLASP N terminal DUF342 PF03961.8 KFM04063.1 - 6.8 4.9 8.3 0.96 7.7 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF342) B3_4 PF03483.12 KFM04064.1 - 1.7e-11 43.8 0.0 3.3e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain LRR_4 PF12799.2 KFM04064.1 - 4.8e-10 38.8 0.0 5.4e-05 22.7 0.0 2.9 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM04064.1 - 5.1e-06 26.1 0.0 2e-05 24.2 0.0 2.1 3 0 0 3 3 3 1 Leucine rich repeat LRR_7 PF13504.1 KFM04064.1 - 0.0054 16.7 0.2 0.19 12.0 0.0 3.6 3 0 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.28 KFM04064.1 - 0.037 14.0 0.0 1.4 9.2 0.0 3.0 2 0 0 2 2 2 0 Leucine Rich Repeat Fez1 PF06818.10 KFM04065.1 - 0.0091 16.0 17.9 0.0091 16.0 12.4 1.9 1 1 1 2 2 2 1 Fez1 Reo_sigmaC PF04582.7 KFM04065.1 - 0.064 12.4 4.1 0.084 12.0 2.9 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein IncA PF04156.9 KFM04065.1 - 0.15 11.6 34.4 0.55 9.8 10.3 2.2 1 1 1 2 2 2 0 IncA protein TACC PF05010.9 KFM04065.1 - 0.44 10.2 24.9 0.73 9.5 7.5 2.5 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) Phage_GP20 PF06810.6 KFM04065.1 - 1 8.7 14.2 0.89 8.9 3.1 2.5 1 1 1 2 2 2 0 Phage minor structural protein GP20 Prominin PF05478.6 KFM04065.1 - 1.8 6.0 12.9 5.8 4.3 8.9 1.7 1 1 0 1 1 1 0 Prominin DUF4407 PF14362.1 KFM04065.1 - 2.7 6.8 12.6 4 6.2 8.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Lebercilin PF15619.1 KFM04065.1 - 3.2 7.1 29.9 0.32 10.4 17.6 1.5 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease CENP-Q PF13094.1 KFM04065.1 - 3.3 7.7 26.2 7.5 6.5 7.8 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit COG5 PF10392.4 KFM04065.1 - 7 6.6 14.3 0.61 10.0 4.2 2.5 1 1 1 2 2 2 0 Golgi transport complex subunit 5 COG2 PF06148.6 KFM04065.1 - 9 6.1 19.6 3.7 7.4 1.9 2.7 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 WD40 PF00400.27 KFM04066.1 - 1.3e-11 43.8 8.8 0.00018 21.2 0.0 7.2 8 0 0 8 8 8 3 WD domain, G-beta repeat eIF2A PF08662.6 KFM04066.1 - 1.2e-08 34.9 0.2 0.07 12.8 0.0 4.4 2 2 3 5 5 5 5 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 KFM04066.1 - 0.00093 17.1 1.5 0.81 7.4 0.0 3.2 2 1 0 4 4 4 2 IKI3 family hSac2 PF12456.3 KFM04067.1 - 2.4e-33 113.9 0.1 3.5e-33 113.3 0.1 1.3 1 0 0 1 1 1 1 Inositol phosphatase RhoGEF PF00621.15 KFM04068.1 - 1.9e-35 122.3 1.6 2.7e-35 121.8 1.1 1.2 1 0 0 1 1 1 1 RhoGEF domain SH3_9 PF14604.1 KFM04068.1 - 1.9e-12 46.5 0.3 4.6e-12 45.3 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 KFM04068.1 - 2.3e-08 33.2 0.1 6e-08 31.9 0.1 1.8 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 KFM04068.1 - 3.3e-08 33.6 0.0 1e-07 32.1 0.0 1.8 2 0 0 2 2 2 1 PH domain SH3_2 PF07653.12 KFM04068.1 - 2.3e-07 30.1 0.0 5.7e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain HATPase_c_3 PF13589.1 KFM04068.1 - 0.077 12.6 0.0 1.8 8.1 0.0 2.7 3 0 0 3 3 3 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-C2H2 PF00096.21 KFM04069.1 - 5.6e-49 161.6 89.1 7.8e-07 29.0 0.8 10.5 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM04069.1 - 3.6e-30 102.7 79.6 2.9e-09 36.7 0.9 12.2 13 0 0 13 13 13 7 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM04069.1 - 2e-28 96.6 76.1 0.00028 21.0 0.8 10.5 10 0 0 10 10 10 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM04069.1 - 7e-13 48.3 55.9 0.031 14.4 0.1 10.3 10 0 0 10 10 10 6 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFM04069.1 - 1.5e-12 46.9 69.0 0.014 15.2 0.3 10.4 10 0 0 10 10 10 8 C2H2-type zinc finger zf-BED PF02892.10 KFM04069.1 - 1.3e-05 24.8 7.6 7.2e-05 22.4 0.6 8.6 3 3 5 8 8 8 3 BED zinc finger zf-met PF12874.2 KFM04069.1 - 0.0052 16.9 50.3 0.38 11.0 0.2 9.4 9 0 0 9 9 9 3 Zinc-finger of C2H2 type GAGA PF09237.6 KFM04069.1 - 0.049 13.2 20.2 1.7 8.3 0.3 5.8 3 1 2 5 5 5 0 GAGA factor Peptidase_M13_N PF05649.8 KFM04072.1 - 8e-134 446.5 6.5 1.4e-133 445.7 4.5 1.4 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 KFM04072.1 - 1.5e-65 220.2 0.0 2.6e-65 219.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M48 PF01435.13 KFM04072.1 - 0.065 12.7 0.0 0.18 11.3 0.0 1.8 1 1 0 1 1 1 0 Peptidase family M48 HLH PF00010.21 KFM04073.1 - 6.5e-15 54.5 2.0 1.1e-14 53.7 1.4 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.8 KFM04073.1 - 2e-08 33.8 0.6 3.8e-08 32.9 0.4 1.4 1 0 0 1 1 1 1 Hairy Orange Translin PF01997.11 KFM04073.1 - 0.0017 17.9 1.7 0.0021 17.6 1.2 1.1 1 0 0 1 1 1 1 Translin family HLH PF00010.21 KFM04074.1 - 2.7e-14 52.6 1.7 4.7e-14 51.8 1.2 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.8 KFM04074.1 - 0.00065 19.3 0.1 0.0011 18.6 0.1 1.4 1 0 0 1 1 1 1 Hairy Orange RNA_pol_Rpb4 PF03874.11 KFM04074.1 - 0.091 12.7 2.1 0.13 12.3 1.5 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb4 DUF1474 PF07342.6 KFM04074.1 - 0.11 12.7 0.3 0.19 12.0 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1474) HLH PF00010.21 KFM04075.1 - 9.6e-15 54.0 2.9 1.7e-14 53.2 2.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.8 KFM04075.1 - 1.6e-08 34.1 0.3 2.5e-08 33.4 0.2 1.3 1 0 0 1 1 1 1 Hairy Orange Fumble PF03630.9 KFM04076.1 - 5e-137 456.3 3.8 6.3e-137 455.9 2.7 1.1 1 0 0 1 1 1 1 Fumble DUF89 PF01937.14 KFM04076.1 - 8.5e-57 192.5 0.0 1.3e-56 191.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF89 Lig_chan PF00060.21 KFM04077.1 - 1.5e-40 138.3 0.3 2.4e-40 137.6 0.2 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.15 KFM04077.1 - 3.1e-21 75.6 0.0 4.4e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.4 KFM04077.1 - 4.3e-21 74.6 0.0 9.9e-21 73.4 0.0 1.6 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site PI-PLC-X PF00388.14 KFM04078.1 - 1.2e-64 216.0 0.1 2.4e-64 215.1 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KFM04078.1 - 3.3e-44 149.6 1.0 1.1e-43 147.9 0.7 2.0 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 KFM04078.1 - 6.8e-24 83.7 0.6 5.7e-23 80.7 0.1 2.6 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 KFM04078.1 - 1e-15 57.3 0.0 2.5e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.1 KFM04078.1 - 2.7e-13 49.8 3.7 1.5e-11 44.2 0.3 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KFM04078.1 - 1e-07 30.7 6.2 0.00041 19.4 0.0 3.5 3 1 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 KFM04078.1 - 2.4e-06 26.9 3.3 0.056 13.3 0.0 3.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_10 PF14788.1 KFM04078.1 - 1.7e-05 24.4 0.5 7.9e-05 22.2 0.1 2.4 1 1 1 2 2 2 1 EF hand EF-hand_8 PF13833.1 KFM04078.1 - 6e-05 22.5 3.9 0.0097 15.5 0.4 3.5 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 KFM04078.1 - 0.00026 20.1 1.0 0.0026 17.0 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_4 PF12763.2 KFM04078.1 - 0.0043 16.7 0.4 0.028 14.1 0.0 2.5 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Mcp5_PH PF12814.2 KFM04078.1 - 0.0085 16.0 0.0 0.042 13.7 0.0 2.3 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology SPARC_Ca_bdg PF10591.4 KFM04078.1 - 0.009 16.0 0.0 0.031 14.3 0.0 1.9 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Pex2_Pex12 PF04757.9 KFM04079.1 - 2.8e-34 118.5 3.4 3.3e-34 118.2 2.3 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 KFM04079.1 - 1.3e-07 31.5 7.8 2.5e-07 30.5 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM04079.1 - 3.8e-06 26.6 9.9 8.1e-06 25.5 6.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KFM04079.1 - 1.3e-05 24.7 8.1 2.9e-05 23.6 5.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM04079.1 - 9.1e-05 22.0 7.8 0.00014 21.4 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF3290 PF11694.3 KFM04079.1 - 0.00077 19.2 0.1 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3290) zf-RING_5 PF14634.1 KFM04079.1 - 0.00082 19.0 9.2 0.0017 18.0 6.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KFM04079.1 - 0.0041 16.8 4.2 0.0093 15.6 2.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KFM04079.1 - 0.009 15.8 7.2 0.028 14.2 4.8 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING Methyltrans_Mon PF14314.1 KFM04079.1 - 0.02 12.7 0.2 0.03 12.1 0.1 1.1 1 0 0 1 1 1 0 Virus-capping methyltransferase Prok-RING_4 PF14447.1 KFM04079.1 - 0.16 11.4 4.5 0.35 10.4 3.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Rer1 PF03248.8 KFM04080.1 - 9.2e-79 263.1 8.0 1.1e-78 262.9 5.5 1.0 1 0 0 1 1 1 1 Rer1 family DUF2208 PF09973.4 KFM04080.1 - 0.81 8.8 4.5 0.1 11.8 0.3 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) Kinetocho_Slk19 PF12709.2 KFM04081.1 - 0.8 9.8 22.7 0.075 13.1 1.2 4.6 3 1 2 5 5 5 0 Central kinetochore-associated Pkinase PF00069.20 KFM04082.1 - 8.7e-61 205.3 0.0 1.2e-60 204.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM04082.1 - 3e-33 115.0 0.0 5.1e-33 114.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PB1 PF00564.19 KFM04082.1 - 7.3e-15 54.4 0.1 1.7e-14 53.2 0.1 1.6 1 0 0 1 1 1 1 PB1 domain C1_1 PF00130.17 KFM04082.1 - 3.8e-14 52.1 6.6 7.7e-14 51.1 4.6 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 KFM04082.1 - 8.7e-07 29.3 0.7 1.8e-06 28.3 0.5 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KFM04082.1 - 1.5e-05 24.0 0.0 2.1e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFM04082.1 - 0.012 14.7 0.0 0.031 13.3 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family C1_3 PF07649.7 KFM04082.1 - 0.17 11.9 1.3 0.54 10.3 0.9 1.9 1 0 0 1 1 1 0 C1-like domain Neur_chan_LBD PF02931.18 KFM04083.1 - 4.6e-51 173.0 0.1 7.8e-51 172.2 0.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFM04083.1 - 2.2e-41 142.2 2.4 4.6e-36 124.8 1.1 2.6 2 1 1 3 3 3 2 Neurotransmitter-gated ion-channel transmembrane region PapD-like PF14874.1 KFM04084.1 - 9.5e-06 25.4 0.0 0.16 11.8 0.0 2.6 2 0 0 2 2 2 2 Flagellar-associated PapD-like Motile_Sperm PF00635.21 KFM04084.1 - 0.012 15.2 0.1 2.8 7.5 0.0 3.1 3 0 0 3 3 3 0 MSP (Major sperm protein) domain TMEM52 PF14979.1 KFM04086.1 - 8.4e-30 103.7 1.5 9e-30 103.6 1.0 1.0 1 0 0 1 1 1 1 Transmembrane 52 Hum_adeno_E3A PF05393.6 KFM04086.1 - 0.13 11.9 0.4 0.14 11.8 0.3 1.1 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein Corona_S2 PF01601.11 KFM04086.1 - 0.24 9.4 2.0 0.25 9.3 1.4 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein NAD_kinase PF01513.16 KFM04087.1 - 9.7e-63 211.6 0.1 1.4e-62 211.1 0.1 1.2 1 0 0 1 1 1 1 ATP-NAD kinase TPT PF03151.11 KFM04089.1 - 9.3e-33 113.0 8.8 9.3e-33 113.0 6.1 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 KFM04089.1 - 8.3e-15 54.9 26.5 5.1e-08 33.0 5.1 2.6 2 1 1 3 3 3 2 EamA-like transporter family UAA PF08449.6 KFM04089.1 - 5.5e-09 35.3 25.1 1.3e-08 34.1 17.4 1.6 1 1 0 1 1 1 1 UAA transporter family Pkinase PF00069.20 KFM04090.1 - 3e-67 226.5 0.0 3e-67 226.5 0.0 2.2 3 1 1 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM04090.1 - 3.6e-30 104.8 0.3 1.1e-29 103.3 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM04090.1 - 2e-05 23.7 3.0 0.00018 20.5 0.0 2.6 2 1 1 3 3 3 2 Kinase-like Peptidase_M10 PF00413.19 KFM04091.1 - 1.8e-38 131.6 0.3 2.5e-38 131.2 0.2 1.2 1 0 0 1 1 1 1 Matrixin ShK PF01549.19 KFM04091.1 - 1.1e-08 35.2 7.6 2e-08 34.4 5.2 1.5 1 0 0 1 1 1 1 ShK domain-like Ig_2 PF13895.1 KFM04091.1 - 4e-06 26.8 0.0 8.1e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFM04091.1 - 0.00033 20.5 0.4 0.0036 17.1 0.3 2.2 1 1 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 KFM04091.1 - 0.017 14.9 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin I-set domain Reprolysin_4 PF13583.1 KFM04091.1 - 0.019 14.4 0.1 0.032 13.7 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF3152 PF11350.3 KFM04091.1 - 0.021 14.3 0.1 0.037 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3152) Reprolysin_3 PF13582.1 KFM04091.1 - 0.034 14.6 1.9 0.054 14.0 1.3 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KFM04091.1 - 0.036 13.9 1.6 0.19 11.6 1.3 1.8 1 1 1 2 2 2 0 Metallo-peptidase family M12 Peptidase_M54 PF07998.6 KFM04091.1 - 0.061 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M54 Reprolysin_2 PF13574.1 KFM04091.1 - 0.062 13.3 1.9 0.1 12.6 1.3 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 KFM04091.1 - 0.1 11.4 0.2 0.16 10.8 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Astacin PF01400.19 KFM04091.1 - 0.17 11.2 3.4 0.53 9.6 1.2 2.6 3 1 1 4 4 4 0 Astacin (Peptidase family M12A) Crisp PF08562.5 KFM04091.1 - 0.66 10.2 3.7 1.6 9.0 2.6 1.6 1 0 0 1 1 1 0 Crisp Ank_2 PF12796.2 KFM04092.1 - 2e-53 178.6 11.6 4.2e-17 62.2 0.6 5.3 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) MIB_HERC2 PF06701.8 KFM04092.1 - 4.6e-53 177.0 21.4 1e-27 95.8 3.1 3.2 2 0 0 2 2 2 2 Mib_herc2 Ank PF00023.25 KFM04092.1 - 8.1e-52 170.5 9.9 3.9e-08 32.7 0.1 8.9 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.1 KFM04092.1 - 1.1e-45 152.6 11.2 1e-10 41.4 0.2 7.6 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFM04092.1 - 2.7e-40 136.0 8.6 9.4e-10 38.7 0.1 6.8 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM04092.1 - 1.7e-34 114.4 10.3 6.6e-06 25.8 0.1 9.8 10 0 0 10 10 10 5 Ankyrin repeat zf-C3HC4_3 PF13920.1 KFM04092.1 - 1e-10 41.1 26.8 5.4e-07 29.1 5.5 3.6 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) ZZ PF00569.12 KFM04092.1 - 2.2e-08 33.5 11.1 2.2e-08 33.5 7.7 3.0 3 0 0 3 3 3 1 Zinc finger, ZZ type DUF3584 PF12128.3 KFM04093.1 - 6.7 3.9 29.3 9.1 3.4 20.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc24 PF08286.6 KFM04093.1 - 9.4 5.9 24.2 8.1 6.1 3.8 3.0 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 Ssu72 PF04722.8 KFM04095.1 - 2.9e-73 245.3 0.1 3.2e-73 245.2 0.1 1.0 1 0 0 1 1 1 1 Ssu72-like protein TPR_MLP1_2 PF07926.7 KFM04095.1 - 0.073 12.8 0.5 1.3 8.8 0.0 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein TMEM240 PF15207.1 KFM04096.1 - 6.7e-63 211.5 2.4 8e-63 211.2 1.6 1.0 1 0 0 1 1 1 1 TMEM240 family DUF3523 PF12037.3 KFM04097.1 - 1.3e-80 270.3 29.7 1.3e-80 270.3 20.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3523) AAA PF00004.24 KFM04097.1 - 1.9e-21 76.6 0.0 6.3e-21 74.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KFM04097.1 - 4.5e-07 30.7 1.4 2.4e-06 28.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KFM04097.1 - 0.00014 21.0 0.2 0.0037 16.4 0.0 2.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 KFM04097.1 - 0.00027 21.0 8.2 0.044 13.9 0.0 3.4 2 2 1 3 3 2 2 AAA domain AAA_25 PF13481.1 KFM04097.1 - 0.00039 19.8 1.2 0.00069 19.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KFM04097.1 - 0.00069 18.7 0.0 0.0024 16.9 0.0 2.1 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 KFM04097.1 - 0.0015 18.4 0.0 0.0015 18.4 0.0 2.7 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 KFM04097.1 - 0.0017 17.7 0.1 0.015 14.7 0.0 2.5 2 1 1 3 3 3 1 IstB-like ATP binding protein KaiC PF06745.8 KFM04097.1 - 0.0024 17.0 1.4 0.0041 16.2 0.0 2.0 2 1 0 2 2 2 1 KaiC Zot PF05707.7 KFM04097.1 - 0.0031 17.0 6.4 0.0071 15.8 0.3 3.1 2 1 0 2 2 2 1 Zonular occludens toxin (Zot) Ycf1 PF05758.7 KFM04097.1 - 0.005 14.6 2.2 0.005 14.6 1.5 1.2 1 0 0 1 1 1 1 Ycf1 AAA_5 PF07728.9 KFM04097.1 - 0.01 15.5 4.7 0.034 13.8 0.0 3.4 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KFM04097.1 - 0.015 15.0 0.0 0.058 13.1 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain AAA_24 PF13479.1 KFM04097.1 - 0.025 14.1 0.1 0.025 14.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KFM04097.1 - 0.028 14.5 0.0 0.07 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 KFM04097.1 - 0.036 13.7 0.3 0.34 10.5 0.0 2.5 3 0 0 3 3 3 0 NACHT domain AAA_16 PF13191.1 KFM04097.1 - 0.17 11.8 0.0 0.17 11.8 0.0 3.7 2 2 0 3 3 2 0 AAA ATPase domain AAA_18 PF13238.1 KFM04097.1 - 0.24 11.6 2.9 0.5 10.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KFM04097.1 - 0.42 10.5 15.5 0.43 10.5 0.0 3.5 2 2 1 3 3 3 0 AAA domain AAA_11 PF13086.1 KFM04097.1 - 0.98 8.9 0.0 0.98 8.9 0.0 3.0 2 1 0 2 2 1 0 AAA domain HlyD_2 PF12700.2 KFM04097.1 - 1.1 8.3 7.9 2.5 7.1 5.5 1.6 1 0 0 1 1 1 0 HlyD family secretion protein AAA_10 PF12846.2 KFM04097.1 - 1.7 8.0 5.8 1.4 8.2 0.0 2.8 3 0 0 3 3 3 0 AAA-like domain VWA PF00092.23 KFM04098.1 - 9.9e-37 126.3 0.0 1.9e-36 125.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain fn3 PF00041.16 KFM04098.1 - 4.9e-22 77.8 1.7 4e-10 39.6 0.1 2.3 2 0 0 2 2 2 2 Fibronectin type III domain VWA_2 PF13519.1 KFM04098.1 - 3.3e-15 56.6 0.0 5.3e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Interfer-bind PF09294.5 KFM04098.1 - 7.2e-06 25.9 0.1 0.016 15.2 0.0 2.4 2 0 0 2 2 2 2 Interferon-alpha/beta receptor, fibronectin type III Big_5 PF13205.1 KFM04098.1 - 0.0029 18.1 2.3 1.5 9.4 0.0 3.4 3 1 0 3 3 3 1 Bacterial Ig-like domain DUF1410 PF07198.6 KFM04098.1 - 0.036 14.3 0.4 4.6 7.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1410) VWA_CoxE PF05762.9 KFM04098.1 - 0.038 13.1 0.1 0.13 11.3 0.0 1.9 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein DUF2369 PF10179.4 KFM04098.1 - 0.05 12.7 0.2 0.51 9.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2369) DUF2852 PF11014.3 KFM04099.1 - 1.2 9.0 4.7 0.27 11.1 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) DUF3661 PF12400.3 KFM04099.1 - 5.9 6.9 10.5 17 5.5 5.5 2.1 1 1 1 2 2 2 0 Vaculolar membrane protein Ribosomal_L20 PF00453.13 KFM04100.1 - 7e-31 106.3 2.5 8.9e-31 106.0 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L20 Cyclin_N PF00134.18 KFM04101.1 - 2.7e-13 49.5 1.0 1.4e-07 31.0 0.1 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFM04101.1 - 3.1e-06 27.0 0.1 3.1e-06 27.0 0.1 2.5 3 0 0 3 3 3 1 Cyclin, C-terminal domain TFIIB PF00382.14 KFM04101.1 - 6.5e-05 22.6 0.4 0.11 12.3 0.1 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat E2F_TDP PF02319.15 KFM04101.1 - 0.03 13.8 0.1 0.092 12.3 0.0 1.9 2 0 0 2 2 2 0 E2F/DP family winged-helix DNA-binding domain DUF2779 PF11074.3 KFM04101.1 - 0.064 13.2 1.3 3.6 7.6 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function(DUF2779) adh_short PF00106.20 KFM04102.1 - 1.3e-09 38.1 0.0 2.2e-09 37.4 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFM04102.1 - 2e-08 34.3 0.1 2.5e-08 33.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFM04102.1 - 0.034 13.8 0.2 0.045 13.4 0.1 1.3 1 0 0 1 1 1 0 KR domain DUF1713 PF08213.6 KFM04103.1 - 7.9e-12 44.5 19.7 7.9e-12 44.5 13.6 1.9 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) ScpA_ScpB PF02616.9 KFM04103.1 - 0.14 11.7 3.3 0.2 11.2 2.3 1.1 1 0 0 1 1 1 0 ScpA/B protein V-set PF07686.12 KFM04104.1 - 4.8e-20 71.5 0.9 1.1e-10 41.3 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin V-set domain I-set PF07679.11 KFM04104.1 - 4.3e-08 32.9 0.0 0.016 15.0 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM04104.1 - 3.9e-07 30.1 0.2 0.0047 17.0 0.1 2.6 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 KFM04104.1 - 3.5e-06 27.0 0.1 0.045 13.8 0.0 3.0 3 1 0 3 3 3 2 Immunoglobulin domain Ig_3 PF13927.1 KFM04104.1 - 3.5e-06 27.4 1.7 0.15 12.6 0.0 3.7 4 0 0 4 4 4 2 Immunoglobulin domain FixQ PF05545.6 KFM04104.1 - 0.0043 16.6 0.5 0.0081 15.7 0.4 1.4 1 0 0 1 1 1 1 Cbb3-type cytochrome oxidase component FixQ Receptor_2B4 PF11465.3 KFM04104.1 - 0.008 16.0 0.0 2.4 8.1 0.0 3.0 3 0 0 3 3 3 1 Natural killer cell receptor 2B4 TMEM154 PF15102.1 KFM04104.1 - 0.013 15.2 0.1 0.022 14.4 0.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family V-set_CD47 PF08204.6 KFM04104.1 - 0.034 13.9 0.5 0.87 9.3 0.1 2.6 3 0 0 3 3 3 0 CD47 immunoglobulin-like domain DUF347 PF03988.7 KFM04104.1 - 0.044 13.6 0.6 0.078 12.8 0.4 1.3 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Lamp PF01299.12 KFM04104.1 - 2.4 7.2 4.4 14 4.7 1.3 2.2 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) Dsh_C PF12316.3 KFM04105.1 - 1.3e-81 273.6 28.1 1.3e-81 273.6 19.5 2.9 2 1 1 3 3 3 1 Segment polarity protein dishevelled (Dsh) C terminal Dishevelled PF02377.10 KFM04105.1 - 9.7e-24 83.3 11.0 9.7e-24 83.3 7.6 3.2 3 0 0 3 3 3 1 Dishevelled specific domain PDZ PF00595.19 KFM04105.1 - 3.5e-21 75.1 0.3 5.9e-21 74.4 0.2 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) DEP PF00610.16 KFM04105.1 - 1.1e-16 60.2 0.1 2.4e-16 59.2 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PDZ_2 PF13180.1 KFM04105.1 - 0.0016 18.2 0.2 0.0032 17.3 0.2 1.5 1 0 0 1 1 1 1 PDZ domain Shufflon_N PF04917.7 KFM04105.1 - 0.032 13.3 0.1 0.051 12.6 0.1 1.2 1 0 0 1 1 1 0 Bacterial shufflon protein, N-terminal constant region SpoIIIAH PF12685.2 KFM04105.1 - 0.35 10.3 3.0 0.21 11.0 0.1 1.9 2 0 0 2 2 2 0 SpoIIIAH-like protein CDC45 PF02724.9 KFM04105.1 - 6.3 4.7 10.8 0.34 8.9 2.0 2.0 2 0 0 2 2 2 0 CDC45-like protein GLTP PF08718.6 KFM04106.1 - 2.5e-25 89.2 0.0 2.9e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Beta-Casp PF10996.3 KFM04107.1 - 4.7e-28 97.6 0.0 1.5e-27 95.9 0.0 1.9 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.7 KFM04107.1 - 6.3e-15 54.7 0.0 1.5e-14 53.5 0.0 1.7 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 KFM04107.1 - 7.7e-14 51.7 0.2 2.8e-13 49.9 0.1 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KFM04107.1 - 8.2e-11 41.8 1.2 5.2e-09 35.9 0.1 2.8 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KFM04107.1 - 5e-05 23.0 0.0 0.00035 20.3 0.0 2.4 3 1 0 3 3 3 1 Beta-lactamase superfamily domain PseudoU_synth_1 PF01416.15 KFM04108.1 - 4e-29 101.1 0.0 2.5e-16 60.0 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase ArfGap PF01412.13 KFM04109.1 - 5.1e-42 142.3 0.4 1.7e-41 140.7 0.3 1.9 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ank_2 PF12796.2 KFM04109.1 - 2.8e-21 75.6 1.5 3.2e-15 56.2 0.2 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFM04109.1 - 1.1e-14 53.4 2.0 2.7e-05 23.7 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 KFM04109.1 - 1.3e-14 54.2 0.9 5.7e-06 26.6 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) PH PF00169.24 KFM04109.1 - 2.1e-13 50.3 0.3 5.3e-13 49.0 0.2 1.7 1 0 0 1 1 1 1 PH domain Ank_5 PF13857.1 KFM04109.1 - 2.6e-12 46.5 1.3 1.7e-08 34.4 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) PH_11 PF15413.1 KFM04109.1 - 8e-08 32.5 0.7 2.9e-05 24.2 1.2 3.6 2 1 0 2 2 2 1 Pleckstrin homology domain Ank_3 PF13606.1 KFM04109.1 - 7.5e-07 28.8 1.5 0.21 11.9 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeat BAR PF03114.13 KFM04109.1 - 0.022 14.2 6.1 0.042 13.3 4.2 1.5 1 0 0 1 1 1 0 BAR domain Hepsin-SRCR PF09272.5 KFM04109.1 - 0.045 13.9 0.2 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 Hepsin, SRCR ASC PF00858.19 KFM04110.1 - 2.7e-107 359.1 8.4 3.2e-107 358.9 5.8 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel DUF2632 PF10943.3 KFM04110.1 - 0.041 13.3 1.8 0.091 12.2 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2632) UQ_con PF00179.21 KFM04111.1 - 2.3e-27 95.1 0.0 3.3e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme C1q PF00386.16 KFM04112.1 - 1.2e-06 28.4 0.0 2.5e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 C1q domain Collagen PF01391.13 KFM04112.1 - 0.0024 17.3 4.3 0.0037 16.7 3.0 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) TNF PF00229.13 KFM04112.1 - 0.0072 15.8 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family Galactosyl_T PF01762.16 KFM04113.1 - 3.3e-28 98.6 0.0 4.4e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase EF-hand_7 PF13499.1 KFM04114.1 - 6.2e-21 74.3 11.4 1.1e-07 31.9 0.2 3.8 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 KFM04114.1 - 2.2e-20 70.3 8.7 0.00074 18.6 0.0 6.3 6 0 0 6 6 6 5 EF hand EF-hand_6 PF13405.1 KFM04114.1 - 7.3e-14 50.3 1.6 0.1 12.5 0.0 5.8 6 0 0 6 6 6 4 EF-hand domain EF-hand_5 PF13202.1 KFM04114.1 - 5.1e-12 44.5 2.3 0.0016 17.6 0.0 5.0 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 KFM04114.1 - 2.1e-08 33.6 6.1 0.012 15.1 0.0 5.7 5 1 1 6 6 6 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFM04114.1 - 0.0043 17.0 16.0 0.3 11.1 1.2 3.6 2 1 1 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region Pex14_N PF04695.8 KFM04114.1 - 0.024 14.7 0.1 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DsrC PF04358.8 KFM04114.1 - 0.062 13.5 0.5 0.38 11.0 0.1 2.4 2 1 0 2 2 2 0 DsrC like protein DUF826 PF05696.6 KFM04114.1 - 0.12 12.5 0.6 4.5 7.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF826) TNFR_c6 PF00020.13 KFM04115.1 - 1.3e-12 47.5 26.9 5.8e-08 32.6 7.5 3.3 3 0 0 3 3 3 3 TNFR/NGFR cysteine-rich region GCC2_GCC3 PF07699.8 KFM04115.1 - 0.00085 18.8 19.3 0.015 14.9 0.9 2.6 2 0 0 2 2 2 2 GCC2 and GCC3 NCD3G PF07562.9 KFM04115.1 - 0.36 10.5 17.2 0.93 9.2 1.3 3.1 2 1 1 3 3 3 0 Nine Cysteines Domain of family 3 GPCR Endonuclease_7 PF02945.10 KFM04115.1 - 4.7 6.9 12.0 1.1 9.0 5.8 1.9 1 1 1 2 2 2 0 Recombination endonuclease VII PH PF00169.24 KFM04117.1 - 3.4e-06 27.1 0.0 5.8e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 PH domain DUF4501 PF14946.1 KFM04118.1 - 8.1e-30 103.6 0.5 8.4e-30 103.5 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4501) zf-RING_5 PF14634.1 KFM04119.1 - 2.5e-09 36.7 6.5 2.5e-09 36.7 4.5 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 KFM04119.1 - 1.8e-07 30.9 6.8 1.8e-07 30.9 4.7 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFM04119.1 - 8.7e-07 28.5 4.2 8.7e-07 28.5 2.9 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFM04119.1 - 9.1e-07 28.4 2.9 1.5e-06 27.7 1.4 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 KFM04119.1 - 3.2e-06 26.6 7.0 3.2e-06 26.6 4.9 2.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM04119.1 - 3.2e-06 27.0 7.1 3.2e-06 27.0 4.9 2.3 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFM04119.1 - 1.7e-05 24.6 7.1 7.8e-05 22.4 4.9 2.3 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Baculo_RING PF05883.6 KFM04119.1 - 0.066 13.0 0.3 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-rbx1 PF12678.2 KFM04119.1 - 1 9.4 8.3 0.27 11.3 3.0 2.1 2 1 0 2 2 2 0 RING-H2 zinc finger zf-RING_4 PF14570.1 KFM04119.1 - 1.5 8.4 12.4 0.039 13.5 3.8 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-MIZ PF02891.15 KFM04119.1 - 2 8.0 7.6 13 5.4 5.1 2.5 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger zf-Apc11 PF12861.2 KFM04119.1 - 2.3 8.1 5.3 1.1 9.1 1.2 2.3 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Y_phosphatase PF00102.22 KFM04120.1 - 2e-34 118.9 0.0 2.3e-34 118.7 0.0 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFM04120.1 - 1.7e-06 27.6 0.1 3.7e-06 26.5 0.1 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 KFM04120.1 - 0.00011 22.2 0.1 0.0003 20.8 0.0 1.7 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 KFM04120.1 - 0.0039 17.4 0.1 0.007 16.6 0.0 1.5 2 0 0 2 2 2 1 Tyrosine phosphatase family UPF0254 PF06787.6 KFM04120.1 - 0.098 12.1 0.1 0.12 11.9 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0254) SH2 PF00017.19 KFM04121.1 - 7.8e-27 92.8 0.0 9.2e-27 92.6 0.0 1.1 1 0 0 1 1 1 1 SH2 domain Cbl_N3 PF02762.9 KFM04121.1 - 0.024 14.2 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain SH2 PF00017.19 KFM04122.1 - 1.2e-25 89.1 0.0 1.6e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 SH2 domain Laminin_G_1 PF00054.18 KFM04123.1 - 1.7e-87 290.1 0.0 3.4e-34 117.6 0.0 4.3 3 1 1 4 4 4 4 Laminin G domain Kazal_1 PF00050.16 KFM04123.1 - 8.2e-84 275.4 142.0 2.2e-10 40.3 5.1 11.1 10 0 0 10 10 10 9 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 KFM04123.1 - 1.6e-76 251.9 94.4 1.4e-11 44.1 1.9 10.7 10 0 0 10 10 10 9 Kazal-type serine protease inhibitor domain Laminin_G_2 PF02210.19 KFM04123.1 - 1.9e-59 199.2 0.0 6.4e-23 81.1 0.0 4.3 3 1 1 4 4 4 4 Laminin G domain NtA PF03146.10 KFM04123.1 - 7.8e-56 187.1 0.0 2e-55 185.8 0.0 1.8 1 0 0 1 1 1 1 Agrin NtA domain Laminin_EGF PF00053.19 KFM04123.1 - 9.9e-19 67.0 32.2 6.4e-13 48.4 8.1 16.9 11 5 5 16 16 16 3 Laminin EGF-like (Domains III and V) SEA PF01390.15 KFM04123.1 - 1.2e-16 60.3 0.0 6.2e-16 58.0 0.0 2.0 2 0 0 2 2 2 1 SEA domain EGF PF00008.22 KFM04123.1 - 3.2e-14 52.5 55.2 1.3e-06 28.1 5.5 12.7 12 0 0 12 12 12 4 EGF-like domain Laminin_G_3 PF13385.1 KFM04123.1 - 0.00021 21.5 0.0 0.67 10.1 0.0 2.5 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily Kelch_1 PF01344.20 KFM04124.1 - 2.2e-76 251.1 10.5 4e-17 61.4 0.1 6.7 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.1 KFM04124.1 - 5.2e-47 156.1 5.9 6.3e-10 38.7 0.0 6.4 1 1 5 6 6 6 6 Kelch motif BACK PF07707.10 KFM04124.1 - 4.7e-38 129.1 0.1 9.6e-38 128.1 0.1 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_4 PF13418.1 KFM04124.1 - 3.1e-36 122.9 4.5 1.4e-08 34.3 0.0 6.3 4 2 2 6 6 6 6 Galactose oxidase, central domain BTB PF00651.26 KFM04124.1 - 4.1e-33 113.6 0.6 6.9e-33 112.9 0.1 1.7 2 0 0 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.1 KFM04124.1 - 3e-31 106.8 12.5 4.2e-08 33.1 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.10 KFM04124.1 - 4.2e-26 89.6 2.0 0.00011 21.7 0.1 6.0 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.1 KFM04124.1 - 1.5e-10 40.7 5.5 0.19 11.7 0.0 5.6 5 0 0 5 5 5 4 Kelch motif BA14K PF07886.6 KFM04124.1 - 0.046 13.3 0.7 1.8 8.3 0.0 3.5 4 0 0 4 4 4 0 BA14K-like protein PQQ_3 PF13570.1 KFM04124.1 - 1 9.7 10.8 20 5.6 0.0 5.6 6 0 0 6 6 6 0 PQQ-like domain Noc2 PF03715.8 KFM04125.1 - 2.9e-117 390.8 9.4 2.9e-117 390.8 6.5 1.6 2 0 0 2 2 2 1 Noc2p family SAM_1 PF00536.25 KFM04126.1 - 1.5e-11 44.2 0.0 3.3e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFM04126.1 - 9.9e-11 41.3 0.2 2.3e-10 40.1 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Ste50p-SAM PF09235.5 KFM04126.1 - 0.0037 17.2 0.0 0.0067 16.4 0.0 1.4 1 0 0 1 1 1 1 Ste50p, sterile alpha motif SAM_PNT PF02198.11 KFM04126.1 - 0.011 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Atrophin-1 PF03154.10 KFM04127.1 - 0 1400.4 150.3 0 1400.2 104.2 1.0 1 0 0 1 1 1 1 Atrophin-1 family DUF1682 PF07946.9 KFM04127.1 - 0.0041 16.0 13.0 0.0066 15.3 9.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) CDC45 PF02724.9 KFM04127.1 - 0.15 10.0 1.3 0.21 9.6 0.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Endonuc_Holl PF10107.4 KFM04127.1 - 0.35 10.5 3.8 0.84 9.3 2.7 1.6 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase NARP1 PF12569.3 KFM04127.1 - 4.6 5.8 9.3 6.7 5.3 6.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 UNC-93 PF05978.11 KFM04128.1 - 3.1e-12 46.2 21.5 3.1e-12 46.2 6.2 3.4 2 1 1 3 3 3 2 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 KFM04128.1 - 1.1e-05 24.3 31.7 0.014 14.1 9.7 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFM04128.1 - 3.2e-05 22.5 16.8 0.00063 18.2 2.1 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein Tcp10_C PF07202.8 KFM04129.1 - 1.9e-88 294.6 8.4 2.1e-88 294.5 5.8 1.0 1 0 0 1 1 1 1 T-complex protein 10 C-terminus DUF4520 PF15016.1 KFM04129.1 - 0.0019 17.7 0.5 0.63 9.6 0.0 3.7 1 1 4 5 5 5 2 Domain of unknown function (DUF4520) DUF4176 PF13780.1 KFM04129.1 - 0.0035 17.0 0.2 0.18 11.5 0.0 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF4176) GSHPx PF00255.14 KFM04129.1 - 0.026 13.9 0.1 0.048 13.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione peroxidase DUF2874 PF11396.3 KFM04129.1 - 0.094 12.6 1.5 2.9 7.9 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2874) Hist_deacetyl PF00850.14 KFM04129.1 - 0.1 11.8 0.2 3.3 6.9 0.0 2.1 2 0 0 2 2 2 0 Histone deacetylase domain Rib PF08428.5 KFM04129.1 - 0.58 9.9 5.8 42 4.0 0.0 4.1 3 1 1 5 5 5 0 Rib/alpha-like repeat Ribonuclease_T2 PF00445.13 KFM04131.1 - 2.1e-44 151.4 7.8 2.5e-44 151.1 5.4 1.0 1 0 0 1 1 1 1 Ribonuclease T2 family Spc7_C2 PF15577.1 KFM04131.1 - 0.1 12.2 0.0 0.39 10.4 0.0 1.9 2 0 0 2 2 2 0 Spc7_C2 SPATA6 PF14909.1 KFM04132.1 - 7.8e-42 142.6 0.1 8.6e-42 142.5 0.1 1.0 1 0 0 1 1 1 1 Spermatogenesis-assoc protein 6 CDC37_M PF08565.6 KFM04133.1 - 1.8e-41 141.5 2.7 2.3e-41 141.1 1.5 1.4 1 1 0 1 1 1 1 Cdc37 Hsp90 binding domain ADK PF00406.17 KFM04134.1 - 2.8e-30 105.1 0.0 3.4e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 KFM04134.1 - 1e-16 60.2 0.0 2.1e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 KFM04134.1 - 0.039 14.7 0.1 0.077 13.8 0.0 1.5 1 1 1 2 2 2 0 AAA domain Matrilin_ccoil PF10393.4 KFM04134.1 - 0.065 12.6 0.1 2.9 7.3 0.0 2.3 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Sad1_UNC PF07738.8 KFM04135.1 - 1.5e-34 118.7 0.0 1.6e-34 118.6 0.0 1.0 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal RTC PF01137.16 KFM04136.1 - 2.8e-58 196.4 0.0 3.4e-58 196.1 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 KFM04136.1 - 6.2e-32 109.6 0.0 9.3e-32 109.1 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Pkinase_Tyr PF07714.12 KFM04137.1 - 4.2e-147 488.1 0.0 5.6e-87 291.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 KFM04137.1 - 3.8e-75 252.4 0.0 6.8e-50 169.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.1 KFM04137.1 - 1.1e-05 24.5 0.0 0.00036 19.5 0.0 2.7 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFM04137.1 - 0.00011 21.3 0.3 0.078 12.0 0.1 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFM04137.1 - 0.0019 17.5 1.2 0.19 11.0 0.1 2.5 2 0 0 2 2 2 2 RIO1 family APH PF01636.18 KFM04137.1 - 0.06 13.0 0.0 2.8 7.5 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Insulin PF00049.13 KFM04138.1 - 0.02 15.6 0.2 0.023 15.4 0.2 1.3 1 1 0 1 1 1 0 Insulin/IGF/Relaxin family Ins_beta PF03488.9 KFM04138.1 - 0.045 13.5 0.8 0.067 13.0 0.6 1.3 1 0 0 1 1 1 0 Nematode insulin-related peptide beta type DUF2368 PF10166.4 KFM04139.1 - 5.9e-51 171.4 0.2 6.7e-51 171.3 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2368) V-set PF07686.12 KFM04140.1 - 1.7e-12 47.2 0.2 1.3e-11 44.3 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin V-set domain I-set PF07679.11 KFM04140.1 - 1.5e-11 43.9 0.2 8.7e-06 25.5 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM04140.1 - 4.2e-11 42.8 0.5 1.6e-05 24.9 0.0 2.3 1 1 1 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 KFM04140.1 - 4.6e-10 39.8 0.4 0.00081 19.8 0.1 2.9 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 KFM04140.1 - 1.5e-06 28.1 0.7 0.027 14.5 0.0 3.5 3 1 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.7 KFM04140.1 - 1.3e-05 24.9 0.1 0.00023 21.0 0.1 2.2 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain C1-set PF07654.10 KFM04140.1 - 0.0019 18.1 1.3 0.0088 16.0 0.4 2.2 2 0 0 2 2 2 1 Immunoglobulin C1-set domain Ig_2 PF13895.1 KFM04141.1 - 2.7e-11 43.4 0.2 2.1e-05 24.5 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 KFM04141.1 - 3.5e-08 33.8 0.9 0.00079 19.8 0.1 3.3 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.11 KFM04141.1 - 1.2e-07 31.4 0.1 0.019 14.7 0.0 2.9 2 1 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.12 KFM04141.1 - 2.4e-07 30.6 0.2 1.7e-06 27.9 0.0 2.2 1 1 1 2 2 2 1 Immunoglobulin V-set domain C1-set PF07654.10 KFM04141.1 - 3.2e-06 27.0 0.2 1e-05 25.4 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin C1-set domain ig PF00047.20 KFM04141.1 - 9.5e-06 25.6 0.3 0.0037 17.3 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.7 KFM04141.1 - 1.1e-05 25.2 0.0 2.5e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain RIC1 PF07064.8 KFM04142.1 - 4.8e-90 301.5 0.6 7.7e-90 300.8 0.4 1.3 1 0 0 1 1 1 1 RIC1 Peptidase_M28 PF04389.12 KFM04143.1 - 5.9e-38 130.3 0.0 9.3e-38 129.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KFM04143.1 - 2.3e-08 33.7 0.0 4e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 SGL PF08450.7 KFM04143.1 - 0.0049 16.2 0.0 0.0081 15.5 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Peptidase_M42 PF05343.9 KFM04143.1 - 0.047 12.4 0.0 0.081 11.6 0.0 1.3 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase MFS_1 PF07690.11 KFM04144.1 - 6.6e-35 120.4 39.6 5.1e-24 84.6 17.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFM04144.1 - 1.2e-05 23.9 5.5 1.2e-05 23.9 3.8 3.1 1 1 2 3 3 3 2 MFS/sugar transport protein ATG22 PF11700.3 KFM04144.1 - 1.4e-05 23.8 6.1 1.4e-05 23.8 4.2 2.4 2 1 0 2 2 2 1 Vacuole effluxer Atg22 like DUF1290 PF06947.7 KFM04144.1 - 2.9 7.8 8.6 5.6 6.9 1.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1290) MLANA PF14991.1 KFM04145.1 - 6e-35 119.8 0.0 6.7e-35 119.6 0.0 1.0 1 0 0 1 1 1 1 Protein melan-A DUF4131 PF13567.1 KFM04145.1 - 0.0038 16.6 0.3 0.0039 16.6 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) RCR PF12273.3 KFM04145.1 - 0.083 13.4 0.0 0.11 13.0 0.0 1.1 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red SKG6 PF08693.5 KFM04145.1 - 0.45 9.8 2.1 0.67 9.3 1.5 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain WBP-1 PF11669.3 KFM04145.1 - 2 8.5 4.6 14 5.8 3.2 2.0 1 1 0 1 1 1 0 WW domain-binding protein 1 FYVE_2 PF02318.11 KFM04147.1 - 5.4 6.9 9.6 0.23 11.3 2.1 2.1 2 0 0 2 2 2 0 FYVE-type zinc finger SAD_SRA PF02182.12 KFM04149.1 - 2.3e-53 179.6 0.1 5.5e-53 178.4 0.0 1.7 1 0 0 1 1 1 1 SAD/SRA domain DUF3590 PF12148.3 KFM04149.1 - 5.6e-38 128.4 0.9 2.5e-33 113.5 0.2 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3590) PHD PF00628.24 KFM04149.1 - 7.4e-10 38.3 10.7 7.4e-10 38.3 7.4 3.5 2 2 0 2 2 2 1 PHD-finger zf-C3HC4_2 PF13923.1 KFM04149.1 - 7.6e-05 22.6 13.3 7.6e-05 22.6 9.2 3.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM04149.1 - 0.00028 20.4 13.4 0.00028 20.4 9.3 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM04149.1 - 0.00046 19.8 10.6 0.00046 19.8 7.3 3.7 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM04149.1 - 0.0012 18.5 12.7 0.0012 18.5 8.8 3.4 2 1 0 2 2 2 1 zinc-RING finger domain PHD_2 PF13831.1 KFM04149.1 - 0.0014 17.9 2.6 0.0014 17.9 1.8 3.5 3 0 0 3 3 3 1 PHD-finger ubiquitin PF00240.18 KFM04149.1 - 0.053 12.9 0.1 0.23 10.8 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin family GDC-P PF02347.11 KFM04150.1 - 5.5e-195 648.0 0.0 1.7e-181 603.5 0.0 3.1 3 0 0 3 3 3 3 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 KFM04150.1 - 6.1e-09 35.4 0.0 1.8e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KFM04150.1 - 6.1e-06 25.2 0.1 2.1e-05 23.4 0.1 1.8 2 0 0 2 2 2 1 Aminotransferase class-V Pyridoxal_deC PF00282.14 KFM04150.1 - 0.00083 17.9 0.3 0.017 13.6 0.0 2.2 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.16 KFM04150.1 - 0.0021 17.0 0.0 0.0077 15.2 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KFM04150.1 - 0.11 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 KFM04150.1 - 0.12 10.6 0.0 1 7.5 0.0 2.2 3 0 0 3 3 3 0 Cys/Met metabolism PLP-dependent enzyme zf-HC5HC2H_2 PF13832.1 KFM04151.1 - 9e-38 128.6 6.5 9e-38 128.6 4.5 2.7 3 0 0 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KFM04151.1 - 4.8e-19 68.2 1.9 4.8e-19 68.2 1.3 3.9 3 1 1 4 4 4 1 PHD-like zinc-binding domain PHD_2 PF13831.1 KFM04151.1 - 2e-13 49.3 9.5 2e-13 49.3 6.6 2.7 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 KFM04151.1 - 1.2e-06 28.0 24.0 3.5e-06 26.5 3.4 3.3 3 0 0 3 3 3 2 PHD-finger LBR_tudor PF09465.5 KFM04151.1 - 0.00038 20.0 0.8 0.0066 16.0 0.1 2.5 2 0 0 2 2 2 1 Lamin-B receptor of TUDOR domain CopK PF11525.3 KFM04151.1 - 0.093 12.3 0.0 0.23 11.0 0.0 1.7 1 0 0 1 1 1 0 Copper resistance protein K Y_phosphatase PF00102.22 KFM04152.1 - 5.3e-172 569.2 0.4 5.5e-86 287.7 0.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.16 KFM04152.1 - 1e-117 384.5 29.9 3.3e-16 59.1 1.1 9.6 10 0 0 10 10 10 8 Fibronectin type III domain I-set PF07679.11 KFM04152.1 - 1.1e-39 134.1 0.0 7.4e-15 54.5 0.0 4.5 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM04152.1 - 1.4e-24 86.0 0.1 3.2e-08 33.5 0.0 4.4 4 0 0 4 4 3 3 Immunoglobulin domain Ig_3 PF13927.1 KFM04152.1 - 9.9e-22 77.2 4.5 2.7e-05 24.5 0.0 6.9 7 0 0 7 7 6 3 Immunoglobulin domain Interfer-bind PF09294.5 KFM04152.1 - 1.9e-12 47.1 0.2 0.33 11.0 0.0 7.6 8 0 0 8 8 8 3 Interferon-alpha/beta receptor, fibronectin type III DSPc PF00782.15 KFM04152.1 - 3e-08 33.3 0.0 0.0041 16.7 0.0 2.5 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain V-set PF07686.12 KFM04152.1 - 5.9e-07 29.3 0.0 0.61 9.9 0.0 4.5 3 1 1 4 4 4 2 Immunoglobulin V-set domain Y_phosphatase3 PF13350.1 KFM04152.1 - 1.1e-06 28.9 0.0 0.073 13.3 0.0 2.8 3 0 0 3 3 3 2 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KFM04152.1 - 1.6e-06 28.2 0.1 0.0023 17.9 0.0 2.8 2 0 0 2 2 2 2 Inositol hexakisphosphate DUF2369 PF10179.4 KFM04152.1 - 0.00058 19.0 0.6 17 4.4 0.0 5.2 5 1 0 5 5 5 0 Uncharacterised conserved protein (DUF2369) RNA_pol_Rpb1_6 PF04992.9 KFM04153.1 - 0.054 13.2 0.2 0.066 12.9 0.2 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_6 PF04992.9 KFM04155.1 - 0.055 13.2 0.2 0.073 12.7 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 6 Tyrosinase PF00264.15 KFM04160.1 - 4.7e-33 115.2 0.1 6.4e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Laminin_EGF PF00053.19 KFM04160.1 - 0.15 11.9 12.2 0.42 10.5 6.3 2.8 2 1 0 2 2 2 0 Laminin EGF-like (Domains III and V) hEGF PF12661.2 KFM04160.1 - 0.38 10.9 12.4 1.2 9.3 2.7 2.8 2 0 0 2 2 2 0 Human growth factor-like EGF LURAP PF14854.1 KFM04161.1 - 8e-40 135.3 2.1 1e-39 135.0 1.5 1.1 1 0 0 1 1 1 1 Leucine rich adaptor protein PDZ PF00595.19 KFM04162.1 - 4.1e-170 552.3 64.2 6.4e-17 61.5 0.1 13.3 13 0 0 13 13 13 13 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM04162.1 - 1.1e-55 185.3 39.7 1e-05 25.2 0.1 12.7 12 0 0 12 12 12 12 PDZ domain L27_2 PF09045.5 KFM04162.1 - 7e-30 102.3 4.8 1.5e-29 101.3 3.3 1.6 1 0 0 1 1 1 1 L27_2 L27_1 PF09058.5 KFM04162.1 - 0.0086 15.9 0.4 0.021 14.7 0.3 1.6 1 0 0 1 1 1 1 L27_1 PDZ_1 PF12812.2 KFM04162.1 - 0.035 13.9 0.1 55 3.7 0.0 4.3 4 0 0 4 4 4 0 PDZ-like domain CTF_NFI PF00859.13 KFM04163.1 - 1.2e-116 389.5 30.9 1.7e-116 389.1 21.4 1.1 1 0 0 1 1 1 1 CTF/NF-I family transcription modulation region NfI_DNAbd_pre-N PF10524.4 KFM04163.1 - 4.2e-25 87.0 3.3 7.4e-25 86.2 2.3 1.4 1 0 0 1 1 1 1 Nuclear factor I protein pre-N-terminus MH1 PF03165.11 KFM04163.1 - 1.3e-11 44.3 0.6 2.6e-11 43.4 0.4 1.5 1 0 0 1 1 1 1 MH1 domain zf-DHHC PF01529.15 KFM04164.1 - 2.8e-30 104.9 9.7 2.8e-30 104.9 6.7 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase Transglut_core3 PF13471.1 KFM04164.1 - 0.051 13.3 1.2 0.094 12.5 0.8 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily DAN PF03045.10 KFM04165.1 - 1.9e-35 120.9 9.5 1.9e-35 120.9 6.6 1.5 2 0 0 2 2 2 1 DAN domain Cys_knot PF00007.17 KFM04165.1 - 0.00026 21.0 7.8 0.00039 20.4 5.4 1.2 1 0 0 1 1 1 1 Cystine-knot domain Sclerostin PF05463.6 KFM04165.1 - 0.0015 18.0 3.1 0.0047 16.4 2.1 1.7 1 1 0 1 1 1 1 Sclerostin (SOST) DUF1661 PF07877.6 KFM04165.1 - 0.05 13.1 0.8 0.17 11.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1661) DUF3808 PF10300.4 KFM04166.1 - 5.6e-166 552.7 11.4 7e-166 552.4 7.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_12 PF13424.1 KFM04166.1 - 5.1e-11 42.3 8.3 4.9e-08 32.7 0.1 5.1 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFM04166.1 - 2.3e-07 30.2 14.7 0.017 14.9 0.3 6.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 KFM04166.1 - 2.8e-07 29.8 6.8 0.035 13.7 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFM04166.1 - 3.8e-07 29.6 10.1 0.0006 19.4 0.1 4.3 3 1 0 3 3 3 2 TPR repeat TPR_8 PF13181.1 KFM04166.1 - 0.00088 18.8 8.5 0.27 11.1 0.2 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFM04166.1 - 0.0043 17.4 17.7 0.13 12.7 0.4 7.0 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFM04166.1 - 0.006 16.2 3.6 0.29 11.0 0.2 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFM04166.1 - 0.012 16.2 3.2 23 5.9 0.0 5.4 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFM04166.1 - 0.015 15.9 2.8 24 5.7 0.1 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat B1 PF02246.10 KFM04166.1 - 0.042 13.6 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 Protein L b1 domain TPR_19 PF14559.1 KFM04166.1 - 0.067 13.5 11.6 3.9 7.8 0.0 5.4 5 1 1 6 6 6 0 Tetratricopeptide repeat Apc3 PF12895.2 KFM04166.1 - 1.6 8.9 21.4 1.6 8.9 1.0 4.9 5 2 0 5 5 4 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-SNAP50_C PF12251.3 KFM04167.1 - 1.7e-70 236.4 3.6 2.1e-70 236.1 2.5 1.1 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal LEDGF PF11467.3 KFM04168.1 - 7.2e-40 134.9 6.2 7.2e-40 134.9 4.3 2.6 4 0 0 4 4 4 1 Lens epithelium-derived growth factor (LEDGF) PWWP PF00855.12 KFM04168.1 - 9.5e-18 64.1 0.1 9.5e-18 64.1 0.1 3.8 3 1 0 3 3 3 1 PWWP domain RVT_1 PF00078.22 KFM04169.1 - 0.15 11.3 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2_4 PF13894.1 KFM04170.1 - 6.7e-12 44.8 29.6 0.0097 16.1 0.7 6.8 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2 PF00096.21 KFM04170.1 - 6.2e-09 35.6 33.1 0.0036 17.5 1.0 6.9 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-met PF12874.2 KFM04170.1 - 2.1e-07 30.9 21.1 0.0068 16.5 0.1 5.9 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFM04170.1 - 0.013 15.6 20.9 0.68 10.1 0.4 4.9 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding Arg_repressor PF01316.16 KFM04170.1 - 0.044 13.3 0.0 0.17 11.4 0.0 2.0 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain PGA_cap PF09587.5 KFM04172.1 - 0.0029 16.9 0.1 0.0084 15.4 0.0 1.8 1 1 0 2 2 2 1 Bacterial capsule synthesis protein PGA_cap Baculo_PEP_C PF04513.7 KFM04172.1 - 0.13 12.1 9.9 1.6 8.5 1.6 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 KFM04172.1 - 0.38 9.8 11.3 0.38 9.8 2.6 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DIT1_PvcA PF05141.7 KFM04172.1 - 0.65 9.2 16.8 0.025 13.9 5.7 2.5 1 1 1 3 3 3 0 Pyoverdine/dityrosine biosynthesis protein DUF1811 PF08838.5 KFM04172.1 - 0.89 9.5 6.8 0.091 12.7 0.7 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1811) V-SNARE_C PF12352.3 KFM04172.1 - 1.8 8.6 8.1 6.5 6.9 0.8 3.3 3 2 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus Fib_alpha PF08702.5 KFM04172.1 - 2.6 8.1 22.9 0.45 10.6 6.5 3.2 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Nup54 PF13874.1 KFM04172.1 - 3 7.4 21.9 0.11 12.1 1.3 3.5 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 CENP-Q PF13094.1 KFM04172.1 - 4.8 7.1 37.2 0.27 11.2 12.2 3.2 1 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF948 PF06103.6 KFM04172.1 - 5.6 6.9 15.3 1.8 8.4 2.4 3.4 2 1 2 5 5 5 0 Bacterial protein of unknown function (DUF948) BAR PF03114.13 KFM04174.1 - 1.1e-71 241.0 8.7 1.3e-71 240.8 6.1 1.0 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 KFM04174.1 - 3.3e-15 55.1 0.2 1.4e-14 53.1 0.0 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KFM04174.1 - 8.5e-15 54.0 0.1 1.6e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFM04174.1 - 1.9e-13 49.6 0.0 4e-13 48.6 0.0 1.6 2 0 0 2 2 2 1 Variant SH3 domain BAR_2 PF10455.4 KFM04174.1 - 7.5e-09 34.9 4.4 4.1e-08 32.5 2.2 2.0 2 0 0 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking FH2 PF02181.18 KFM04174.1 - 0.18 10.6 7.2 0.089 11.6 3.1 1.8 2 0 0 2 2 2 0 Formin Homology 2 Domain IMD PF08397.6 KFM04174.1 - 0.18 11.0 5.1 9.2 5.5 0.5 2.4 1 1 1 2 2 2 0 IRSp53/MIM homology domain Exonuc_VII_L PF02601.10 KFM04174.1 - 0.18 10.9 4.0 0.26 10.4 2.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit TSP_1 PF00090.14 KFM04175.1 - 2.7e-24 85.0 68.8 5.1e-06 26.5 2.6 7.6 6 1 0 6 6 6 5 Thrombospondin type 1 domain ADAM_spacer1 PF05986.9 KFM04175.1 - 0.0057 16.4 0.0 0.0086 15.9 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Yae1_N PF09811.4 KFM04176.1 - 1e-07 31.3 25.1 0.026 14.0 16.5 2.9 1 1 0 1 1 1 1 Essential protein Yae1, N terminal I-set PF07679.11 KFM04177.1 - 3.9e-41 138.7 0.0 1.5e-12 47.1 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM04177.1 - 2.3e-28 98.1 0.1 4.6e-10 39.4 0.0 4.1 3 1 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 KFM04177.1 - 2.5e-16 59.8 0.7 3.5e-05 24.2 0.1 3.9 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.20 KFM04177.1 - 3.4e-13 49.4 0.0 1.4e-06 28.2 0.0 3.6 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.12 KFM04177.1 - 1.6e-09 37.6 0.1 0.0011 18.8 0.0 4.6 3 2 0 3 3 3 2 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM04177.1 - 3.3e-08 33.2 0.7 0.18 11.7 0.1 4.2 3 2 0 3 3 3 3 CD80-like C2-set immunoglobulin domain TSP_1 PF00090.14 KFM04177.1 - 3.8e-05 23.7 10.7 3.8e-05 23.7 7.4 5.8 4 1 1 5 5 5 3 Thrombospondin type 1 domain V-set_CD47 PF08204.6 KFM04177.1 - 0.028 14.1 0.2 3.9 7.2 0.0 3.4 3 1 0 3 3 3 0 CD47 immunoglobulin-like domain DUF2890 PF11081.3 KFM04179.1 - 2.1 8.3 5.3 0.79 9.7 2.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2890) Perilipin PF03036.11 KFM04180.1 - 2.2e-162 540.3 18.6 2.6e-162 540.1 12.9 1.0 1 0 0 1 1 1 1 Perilipin family DUF2383 PF09537.5 KFM04180.1 - 0.055 13.7 3.2 2.6 8.3 1.6 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF2383) Tape_meas_lam_C PF09718.5 KFM04180.1 - 1 9.2 6.0 2.8 7.8 0.5 3.5 3 1 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Syntaxin-6_N PF09177.6 KFM04180.1 - 1.7 9.0 7.7 20 5.6 1.7 3.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal YtxH PF12732.2 KFM04180.1 - 7.5 6.9 11.1 22 5.5 0.1 3.6 2 1 0 2 2 2 0 YtxH-like protein DENN PF02141.16 KFM04181.1 - 1.2e-61 207.6 4.1 2.5e-61 206.6 2.8 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 KFM04181.1 - 1.2e-21 76.5 1.2 2.8e-21 75.3 0.8 1.7 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.13 KFM04181.1 - 6.1e-11 42.1 0.4 2e-10 40.4 0.3 2.0 1 0 0 1 1 1 1 uDENN domain PPR_2 PF13041.1 KFM04181.1 - 1.1e-05 25.2 0.0 0.00033 20.5 0.0 2.6 2 0 0 2 2 2 1 PPR repeat family PPR_3 PF13812.1 KFM04181.1 - 0.0086 16.2 0.0 0.089 13.1 0.0 2.5 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR PF01535.15 KFM04181.1 - 0.16 12.0 0.0 0.48 10.5 0.0 1.9 1 0 0 1 1 1 0 PPR repeat Ribosomal_S6e PF01092.14 KFM04182.1 - 1.6e-64 215.2 0.1 1.6e-64 215.2 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein S6e EF-1_beta_acid PF10587.4 KFM04182.1 - 9.9 6.4 10.5 31 4.8 7.3 1.9 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Ceramidase PF05875.7 KFM04183.1 - 9.9e-50 169.1 12.2 1.1e-49 168.9 8.4 1.0 1 0 0 1 1 1 1 Ceramidase Na_Ca_ex PF01699.19 KFM04184.1 - 2.2e-56 189.3 46.2 1.6e-30 105.5 10.5 2.5 3 0 0 3 3 3 2 Sodium/calcium exchanger protein YEATS PF03366.11 KFM04185.1 - 3.1e-10 39.6 0.0 6.3e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 YEATS family DUF3028 PF11229.3 KFM04188.1 - 1.8e-272 904.9 11.1 2.5e-272 904.4 7.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3028) DUF3730 PF12530.3 KFM04188.1 - 4.3e-67 226.4 19.4 8e-55 186.3 1.6 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF3730) PTPLA PF04387.9 KFM04190.1 - 2.2e-41 141.0 7.4 3.3e-41 140.4 5.1 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA DUF3733 PF12534.3 KFM04190.1 - 1.7 7.9 4.9 0.6 9.4 0.8 2.2 2 0 0 2 2 2 0 Leucine-rich repeat containing protein 8 Prion_bPrPp PF11587.3 KFM04190.1 - 3.6 7.3 5.4 21 4.8 0.0 2.8 3 0 0 3 3 3 0 Major prion protein bPrPp - N terminal Interferon PF00143.14 KFM04191.1 - 9.2e-39 132.9 8.2 1.1e-38 132.7 5.7 1.0 1 0 0 1 1 1 1 Interferon alpha/beta domain RVT_1 PF00078.22 KFM04192.1 - 0.01 15.2 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) TLD PF07534.11 KFM04194.1 - 8.3e-41 139.2 0.1 9.5e-41 139.0 0.1 1.0 1 0 0 1 1 1 1 TLD Costars PF14705.1 KFM04195.1 - 2e-33 114.1 0.4 6.6e-33 112.5 0.0 2.0 2 0 0 2 2 2 1 Costars AMP-binding PF00501.23 KFM04197.1 - 5.9e-46 156.7 0.0 8.4e-46 156.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme VDE PF07137.6 KFM04200.1 - 0.22 11.3 1.2 14 5.4 0.2 2.0 1 1 0 2 2 2 0 Violaxanthin de-epoxidase (VDE) PTR2 PF00854.16 KFM04202.1 - 5.1e-83 278.9 8.1 6.1e-83 278.6 5.6 1.1 1 0 0 1 1 1 1 POT family MFS_1 PF07690.11 KFM04202.1 - 2.6e-10 39.5 11.1 5e-10 38.6 7.7 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily Glycos_transf_1 PF00534.15 KFM04203.1 - 9.7e-20 70.6 0.0 1.4e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KFM04203.1 - 5.1e-12 46.0 0.0 1.1e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KFM04203.1 - 7.8e-09 35.6 0.0 1.6e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF1830 PF08865.6 KFM04207.1 - 0.068 12.8 0.0 0.074 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1830) DUF1830 PF08865.6 KFM04208.1 - 0.044 13.4 0.0 0.047 13.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1830) Frizzled PF01534.12 KFM04209.1 - 3.3e-143 476.4 21.7 4.1e-143 476.0 15.1 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.17 KFM04209.1 - 2e-35 121.6 8.9 4.8e-35 120.4 6.2 1.7 1 0 0 1 1 1 1 Fz domain Piwi PF02171.12 KFM04210.1 - 4.4e-106 354.2 0.0 6.3e-106 353.7 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 KFM04210.1 - 2.3e-39 133.7 0.2 4.1e-39 132.9 0.2 1.4 1 0 0 1 1 1 1 PAZ domain SH3_2 PF07653.12 KFM04211.1 - 4.2e-33 112.6 0.0 1.4e-10 40.4 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH3_9 PF14604.1 KFM04211.1 - 1.4e-30 104.5 1.7 8.5e-13 47.6 0.1 3.7 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.23 KFM04211.1 - 2.3e-16 58.9 0.1 1.1e-06 27.9 0.0 4.0 3 1 0 3 3 3 3 SH3 domain fn3 PF00041.16 KFM04211.1 - 8.3e-14 51.4 7.0 0.00015 21.7 0.3 4.1 3 1 0 3 3 3 3 Fibronectin type III domain DUF1423 PF07227.6 KFM04211.1 - 0.48 9.0 5.1 0.74 8.4 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) ADIP PF11559.3 KFM04211.1 - 1.7 8.5 13.0 3.9 7.3 9.0 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Syntaxin PF00804.20 KFM04212.1 - 9.8e-23 80.2 1.2 9.8e-23 80.2 0.8 2.8 2 2 0 2 2 2 1 Syntaxin SNARE PF05739.14 KFM04212.1 - 2.6e-10 39.8 3.5 2.6e-10 39.8 2.4 3.0 2 1 0 2 2 2 1 SNARE domain DUF2216 PF10226.4 KFM04212.1 - 0.021 14.3 1.7 4.4 6.7 0.1 2.6 1 1 1 2 2 2 0 Uncharacterized conserved proteins (DUF2216) SF3b1 PF08920.5 KFM04212.1 - 0.072 13.1 0.7 0.15 12.0 0.5 1.7 1 1 0 1 1 1 0 Splicing factor 3B subunit 1 Syntaxin_2 PF14523.1 KFM04212.1 - 0.11 12.5 12.3 0.036 14.0 3.1 3.1 1 1 1 2 2 2 0 Syntaxin-like protein COG5 PF10392.4 KFM04212.1 - 0.13 12.2 2.7 10 6.0 0.0 2.6 2 1 0 2 2 2 0 Golgi transport complex subunit 5 YlqD PF11068.3 KFM04212.1 - 3.3 7.7 9.7 0.22 11.5 1.3 2.6 1 1 2 3 3 3 0 YlqD protein Syntaxin-6_N PF09177.6 KFM04212.1 - 5.7 7.4 6.7 20 5.6 0.0 3.8 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Ras PF00071.17 KFM04213.1 - 5.3e-50 168.9 0.0 6.3e-50 168.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM04213.1 - 1.9e-17 63.8 0.0 3.3e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM04213.1 - 1.2e-11 44.2 0.0 1.5e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 KFM04213.1 - 0.00021 21.4 0.1 0.00078 19.5 0.1 1.8 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 KFM04213.1 - 0.00041 19.5 0.0 0.00052 19.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFM04213.1 - 0.0014 18.0 0.5 0.022 14.1 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KFM04213.1 - 0.0078 15.4 0.0 0.013 14.7 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KFM04213.1 - 0.016 13.8 1.7 0.76 8.4 0.1 2.7 2 1 1 3 3 3 0 G-protein alpha subunit Pox_A32 PF04665.7 KFM04213.1 - 0.017 14.4 0.1 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein MMR_HSR1 PF01926.18 KFM04213.1 - 0.034 14.0 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Septin PF00735.13 KFM04213.1 - 0.062 12.3 0.0 0.097 11.6 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_22 PF13401.1 KFM04213.1 - 0.063 13.4 0.1 0.34 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KFM04213.1 - 0.067 13.0 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain DRY_EERY PF09750.4 KFM04214.1 - 1e-42 145.0 1.2 1e-42 145.0 0.8 5.0 4 1 1 5 5 5 1 Alternative splicing regulator Surp PF01805.15 KFM04214.1 - 1.2e-29 101.6 8.3 1.3e-14 53.5 0.6 2.5 2 0 0 2 2 2 2 Surp module Hemopexin PF00045.14 KFM04215.1 - 1.4e-49 165.5 21.2 2e-14 52.9 0.4 5.1 5 0 0 5 5 5 4 Hemopexin Peptidase_M10 PF00413.19 KFM04215.1 - 1.8e-47 160.8 0.6 3.4e-47 160.0 0.4 1.4 1 0 0 1 1 1 1 Matrixin PG_binding_1 PF01471.13 KFM04215.1 - 4.2e-14 52.2 0.2 1.2e-13 50.8 0.1 1.8 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Peptidase_M66 PF10462.4 KFM04215.1 - 0.057 12.2 0.1 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase M66 Astacin PF01400.19 KFM04215.1 - 0.058 12.7 1.8 0.64 9.3 0.6 2.3 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Pkinase PF00069.20 KFM04216.1 - 3.3e-64 216.5 0.1 6.7e-64 215.5 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM04216.1 - 6.5e-46 156.4 0.1 1.1e-45 155.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.3 KFM04216.1 - 7.5e-45 153.0 7.8 1.2e-44 152.2 5.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Kdo PF06293.9 KFM04216.1 - 6.3e-06 25.3 0.0 1.3e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KFM04216.1 - 4.6e-05 22.5 0.0 0.00015 20.8 0.0 1.7 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KFM04216.1 - 0.00013 21.3 0.1 0.00024 20.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KFM04216.1 - 0.013 15.2 0.0 0.16 11.7 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family PseudoU_synth_1 PF01416.15 KFM04217.1 - 4e-23 81.8 0.0 3.8e-10 40.1 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase CBF PF03914.12 KFM04219.1 - 4.7e-47 159.4 0.1 7.7e-47 158.7 0.1 1.4 1 0 0 1 1 1 1 CBF/Mak21 family Glycos_transf_2 PF00535.21 KFM04220.1 - 9.5e-24 83.9 0.2 1.9e-23 82.9 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 KFM04220.1 - 4.5e-18 65.4 0.0 7.5e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.1 KFM04220.1 - 9e-08 32.1 0.0 5.2e-07 29.6 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 KFM04220.1 - 0.0001 21.7 0.0 0.00026 20.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFM04220.1 - 0.0072 15.4 0.0 0.012 14.6 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Auts2 PF15336.1 KFM04222.1 - 5.6e-117 389.2 13.5 5.6e-117 389.2 9.4 5.1 5 1 1 6 6 6 1 Autism susceptibility gene 2 protein FHA PF00498.21 KFM04223.1 - 1.9e-15 56.7 0.1 4.3e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 KFM04223.1 - 1.4e-07 31.2 13.9 1.4e-07 31.2 9.6 4.0 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4_3 PF13920.1 KFM04223.1 - 8.9e-07 28.4 13.7 8.9e-07 28.4 9.5 4.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM04223.1 - 4.3e-06 26.6 13.7 4.3e-06 26.6 9.5 4.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM04223.1 - 2.1e-05 24.0 13.2 2.1e-05 24.0 9.1 3.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFM04223.1 - 0.0002 21.4 6.1 0.0002 21.4 4.2 3.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_6 PF14835.1 KFM04223.1 - 0.0005 19.8 9.0 0.0005 19.8 6.2 3.3 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 KFM04223.1 - 0.0024 17.5 15.0 0.0024 17.5 10.4 3.7 3 0 0 3 3 3 1 zinc-RING finger domain Cnl2_NKP2 PF09447.5 KFM04223.1 - 0.16 11.6 0.5 4.8 6.9 0.1 2.8 3 0 0 3 3 3 0 Cnl2/NKP2 family protein PAD PF03068.10 KFM04224.1 - 0.13 10.6 0.0 0.15 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) Reo_sigmaC PF04582.7 KFM04225.1 - 0.0001 21.6 102.2 0.0085 15.3 4.6 9.4 3 2 7 10 10 10 10 Reovirus sigma C capsid protein His_Phos_1 PF00300.17 KFM04226.1 - 1.5e-18 67.3 0.6 2e-17 63.7 0.4 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ran_BP1 PF00638.13 KFM04227.1 - 3.7e-55 185.2 0.4 4.4e-55 184.9 0.3 1.1 1 0 0 1 1 1 1 RanBP1 domain tRNA_U5-meth_tr PF05958.6 KFM04228.1 - 5.5e-18 64.7 0.3 3.5e-17 62.1 0.2 2.1 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 KFM04228.1 - 9.8e-15 54.4 0.1 2e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RRM_6 PF14259.1 KFM04228.1 - 2.7e-09 36.8 0.0 6.9e-09 35.5 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Methyltransf_26 PF13659.1 KFM04228.1 - 3e-09 36.9 0.0 6.6e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFM04228.1 - 4.6e-09 36.8 0.0 9.4e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RRM_5 PF13893.1 KFM04228.1 - 1.2e-08 34.7 0.1 3.4e-08 33.2 0.0 1.9 2 0 0 2 2 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MTS PF05175.9 KFM04228.1 - 1.3e-07 31.1 0.2 2.7e-07 30.1 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase small domain PCMT PF01135.14 KFM04228.1 - 4.3e-07 29.6 0.0 8e-06 25.5 0.0 2.2 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 KFM04228.1 - 6.2e-07 28.6 0.3 1.2e-06 27.6 0.2 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 KFM04228.1 - 1.8e-06 28.2 0.0 6.7e-06 26.4 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain UPF0020 PF01170.13 KFM04228.1 - 6.8e-06 25.7 0.1 0.00017 21.2 0.0 2.2 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 RRM_1 PF00076.17 KFM04228.1 - 1.2e-05 24.8 0.1 2.9e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PrmA PF06325.8 KFM04228.1 - 1.5e-05 24.2 0.2 2.6e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.10 KFM04228.1 - 4.1e-05 23.0 0.0 8.7e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.5 KFM04228.1 - 5.7e-05 22.7 0.0 0.00013 21.5 0.0 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_23 PF13489.1 KFM04228.1 - 7e-05 22.5 0.0 0.00017 21.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFM04228.1 - 9e-05 22.8 0.1 0.00034 21.0 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KFM04228.1 - 0.0003 20.4 0.0 0.00077 19.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 KFM04228.1 - 0.0011 18.6 0.0 0.0021 17.6 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Ubie_methyltran PF01209.13 KFM04228.1 - 0.0012 17.9 0.1 0.0022 17.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 KFM04228.1 - 0.0089 15.1 0.2 0.016 14.3 0.1 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase RrnaAD PF00398.15 KFM04228.1 - 0.019 14.0 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF4371 PF14291.1 KFM04228.1 - 0.03 13.8 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4371) N6_N4_Mtase PF01555.13 KFM04228.1 - 0.032 13.7 2.0 0.045 13.2 0.0 2.0 2 0 0 2 2 2 0 DNA methylase TPMT PF05724.6 KFM04228.1 - 0.043 13.2 0.0 0.086 12.2 0.0 1.5 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_12 PF08242.7 KFM04228.1 - 0.068 13.6 0.0 0.2 12.1 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 KFM04228.1 - 0.073 11.9 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase MetW PF07021.7 KFM04228.1 - 0.078 12.3 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW dsrm PF00035.20 KFM04229.1 - 8.7e-20 71.0 4.6 3.5e-12 46.7 0.0 3.9 3 1 0 3 3 3 2 Double-stranded RNA binding motif WW PF00397.21 KFM04229.1 - 0.0015 18.3 0.0 0.0033 17.2 0.0 1.6 1 0 0 1 1 1 1 WW domain Vps39_1 PF10366.4 KFM04229.1 - 0.1 12.6 0.5 0.34 10.9 0.4 1.9 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 NRDE PF05742.7 KFM04230.1 - 1.2e-09 37.8 0.0 1.2e-09 37.8 0.0 1.0 1 0 0 1 1 1 1 NRDE protein Arm PF00514.18 KFM04231.1 - 1.4e-36 123.1 2.2 1.2e-07 31.3 0.0 7.5 7 0 0 7 7 7 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFM04231.1 - 3.5e-16 59.2 3.0 2.4e-08 34.1 0.0 3.9 4 0 0 4 4 4 2 HEAT repeats Arm_2 PF04826.8 KFM04231.1 - 1.6e-09 37.2 0.3 0.00032 19.8 0.0 4.1 3 1 1 4 4 4 2 Armadillo-like HEAT PF02985.17 KFM04231.1 - 2.7e-08 33.2 0.8 0.59 10.3 0.1 5.2 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 KFM04231.1 - 1.9e-07 31.3 2.4 0.43 11.1 0.1 5.9 6 0 0 6 6 6 2 HEAT-like repeat Atx10homo_assoc PF09759.4 KFM04231.1 - 0.028 14.1 0.0 0.14 11.9 0.0 2.2 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain Methyltransf_3 PF01596.12 KFM04232.1 - 3.4e-23 81.7 0.0 4.6e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 KFM04232.1 - 3.3e-14 53.6 0.0 4.9e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFM04232.1 - 1.4e-08 35.3 0.0 2.5e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFM04232.1 - 6.3e-06 26.2 0.0 8.9e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFM04232.1 - 9.1e-06 25.3 0.0 1.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 KFM04232.1 - 3.9e-05 23.0 0.0 7.5e-05 22.1 0.0 1.4 1 1 1 2 2 2 1 Cephalosporin hydroxylase PCMT PF01135.14 KFM04232.1 - 0.0032 17.0 0.0 0.0049 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14 PF08704.5 KFM04232.1 - 0.025 14.0 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Cons_hypoth95 PF03602.10 KFM04232.1 - 0.11 11.9 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Met_10 PF02475.11 KFM04232.1 - 0.12 12.0 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Pyr_redox_2 PF07992.9 KFM04233.1 - 1.4e-35 122.9 0.0 2.2e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KFM04233.1 - 5.4e-31 106.8 0.0 9.7e-31 106.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 KFM04233.1 - 1.5e-12 47.6 0.3 1.2e-07 32.0 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFM04233.1 - 7.2e-08 31.6 3.5 7.8e-07 28.2 0.3 2.7 2 1 0 3 3 3 1 FAD binding domain Thi4 PF01946.12 KFM04233.1 - 8.9e-06 24.9 0.0 1.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KFM04233.1 - 2.2e-05 23.1 1.3 0.00043 18.8 0.1 2.5 2 1 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 KFM04233.1 - 3.2e-05 22.9 0.8 9.1e-05 21.4 0.6 1.8 1 1 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 KFM04233.1 - 0.00027 20.8 0.4 0.00078 19.4 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KFM04233.1 - 0.00031 19.7 0.2 0.078 11.8 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.2 KFM04233.1 - 0.00031 19.9 0.3 0.00065 18.8 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.19 KFM04233.1 - 0.0006 18.8 1.2 0.00092 18.2 0.3 1.6 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KFM04233.1 - 0.0014 18.7 0.2 0.011 15.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KFM04233.1 - 0.077 11.8 0.5 0.25 10.2 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Nup35_RRM_2 PF14605.1 KFM04233.1 - 0.081 12.7 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF1775 PF07987.6 KFM04233.1 - 0.087 12.6 1.0 12 5.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unkown function (DUF1775) WD40 PF00400.27 KFM04234.1 - 1.7e-26 91.0 5.2 7.7e-08 31.9 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat RAB3GAP2_N PF14655.1 KFM04234.1 - 0.038 12.9 0.0 0.057 12.4 0.0 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus LRR_8 PF13855.1 KFM04236.1 - 8.9e-07 28.5 0.0 1.6e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Leucine rich repeat LRRNT PF01462.13 KFM04236.1 - 6.2e-05 22.3 2.0 6.2e-05 22.3 1.4 2.4 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_4 PF12799.2 KFM04236.1 - 0.00061 19.3 0.1 0.001 18.6 0.1 1.4 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM04236.1 - 0.0014 18.3 0.7 0.1 12.7 0.1 2.8 2 0 0 2 2 2 1 Leucine Rich Repeat DUF948 PF06103.6 KFM04236.1 - 0.0038 17.0 0.1 0.01 15.6 0.1 1.7 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF948) Foamy_virus_ENV PF03408.9 KFM04236.1 - 0.092 10.2 4.9 0.12 9.9 3.4 1.1 1 0 0 1 1 1 0 Foamy virus envelope protein DUF1324 PF07038.6 KFM04236.1 - 7.5 6.6 8.4 4.4 7.4 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1324) Tetraspannin PF00335.15 KFM04236.1 - 8.7 5.5 11.2 0.42 9.8 3.5 1.8 1 1 1 2 2 2 0 Tetraspanin family Septin PF00735.13 KFM04238.1 - 9.4e-128 425.1 0.4 1.1e-127 424.9 0.2 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KFM04238.1 - 5.8e-07 29.4 0.0 1e-06 28.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KFM04238.1 - 1.7e-06 27.2 0.0 3.7e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KFM04238.1 - 1.9e-05 24.2 0.1 0.0087 15.5 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.11 KFM04238.1 - 0.0008 18.5 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 KFM04238.1 - 0.001 18.9 1.5 0.14 11.9 0.0 2.6 1 1 1 2 2 2 2 Dynamin family AAA_10 PF12846.2 KFM04238.1 - 0.0024 17.3 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain Ras PF00071.17 KFM04238.1 - 0.0063 15.9 0.1 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 Ras family AAA_16 PF13191.1 KFM04238.1 - 0.021 14.8 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 KFM04238.1 - 0.025 14.0 0.0 0.062 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KFM04238.1 - 0.032 14.5 0.2 0.054 13.7 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.1 KFM04238.1 - 0.046 13.8 0.0 0.092 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KFM04238.1 - 0.05 13.0 0.0 0.23 10.9 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family Miro PF08477.8 KFM04238.1 - 0.051 14.0 0.1 0.13 12.8 0.0 1.7 2 0 0 2 2 2 0 Miro-like protein AAA_23 PF13476.1 KFM04238.1 - 0.7 10.1 3.2 3.3 8.0 2.4 1.8 1 1 0 1 1 1 0 AAA domain CDC45 PF02724.9 KFM04239.1 - 2.4e-180 600.6 18.2 1.9e-178 594.3 12.6 2.7 1 1 0 1 1 1 1 CDC45-like protein CLAMP PF14769.1 KFM04239.1 - 0.04 14.0 0.3 0.36 11.0 0.0 2.5 2 0 0 2 2 2 0 Flagellar C1a complex subunit C1a-32 UFD1 PF03152.9 KFM04240.1 - 2.8e-81 270.8 0.0 3.4e-81 270.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 KFM04240.1 - 0.017 14.7 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 MRP-L28 PF09812.4 KFM04241.1 - 2.7e-50 170.2 7.8 3.1e-50 170.0 5.4 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 CP2 PF04516.10 KFM04241.1 - 0.0083 15.1 0.6 0.011 14.7 0.3 1.3 1 1 0 1 1 1 1 CP2 transcription factor ToxN_toxin PF13958.1 KFM04241.1 - 0.043 13.4 3.0 0.066 12.8 2.1 1.3 1 0 0 1 1 1 0 Toxin ToxN, type III toxin-antitoxin system DUF4207 PF13904.1 KFM04241.1 - 0.62 9.3 11.1 1 8.6 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) FAM60A PF15396.1 KFM04241.1 - 0.98 9.1 4.7 1.6 8.4 3.2 1.3 1 1 0 1 1 1 0 Protein Family FAM60A Hira PF07569.6 KFM04242.1 - 7.2e-59 198.6 0.1 1.9e-58 197.2 0.1 1.8 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.27 KFM04242.1 - 3.8e-40 134.3 25.9 3.1e-09 36.3 3.1 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat HIRA_B PF09453.5 KFM04242.1 - 1e-08 34.4 0.1 2.4e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 HIRA B motif Pro_isomerase PF00160.16 KFM04243.1 - 1.3e-49 168.3 0.2 2.9e-49 167.2 0.1 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 KFM04243.1 - 2.8e-05 23.4 0.2 2.8e-05 23.4 0.2 2.2 2 1 0 2 2 2 1 Rtf2 RING-finger U-box PF04564.10 KFM04243.1 - 0.0047 16.8 0.0 0.016 15.1 0.0 2.0 1 0 0 1 1 1 1 U-box domain Yippee-Mis18 PF03226.9 KFM04244.1 - 2.5e-17 62.6 0.4 3.7e-17 62.1 0.3 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-CHY PF05495.7 KFM04244.1 - 0.045 13.9 7.2 0.36 11.0 5.0 2.0 1 1 1 2 2 2 0 CHY zinc finger Evr1_Alr PF04777.8 KFM04244.1 - 0.051 13.4 1.2 0.43 10.5 0.2 2.1 2 0 0 2 2 2 0 Erv1 / Alr family Pkinase PF00069.20 KFM04245.1 - 1.1e-25 90.3 0.0 1.2e-25 90.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM04245.1 - 1.3e-11 44.0 0.0 1.6e-11 43.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase COesterase PF00135.23 KFM04246.1 - 1.2e-188 628.1 0.1 1.6e-188 627.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFM04246.1 - 5.7e-07 29.3 0.1 2.8e-06 27.0 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Sarcoglycan_2 PF05510.8 KFM04246.1 - 0.013 13.8 0.2 0.027 12.7 0.0 1.5 2 0 0 2 2 2 0 Sarcoglycan alpha/epsilon DUF1649 PF07855.7 KFM04248.1 - 7.6e-53 178.5 0.1 9.6e-53 178.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) tRNA_lig_CPD PF08302.6 KFM04248.1 - 0.021 14.0 0.9 0.86 8.7 0.0 2.4 3 0 0 3 3 3 0 Fungal tRNA ligase phosphodiesterase domain Pro_3_hydrox_C PF05373.6 KFM04248.1 - 0.074 13.0 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 L-proline 3-hydroxylase, C-terminal Hormone_recep PF00104.25 KFM04249.1 - 4.6e-19 68.3 0.0 6.4e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFM04249.1 - 9.1e-15 54.6 7.2 1.7e-14 53.7 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Pkinase PF00069.20 KFM04250.1 - 1.8e-52 178.0 0.0 2.2e-52 177.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM04250.1 - 2e-33 115.5 0.0 2.8e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TGF_beta_GS PF08515.7 KFM04250.1 - 2.4e-15 55.5 0.2 4.8e-15 54.5 0.1 1.5 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif APH PF01636.18 KFM04250.1 - 0.0023 17.7 0.0 0.011 15.4 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 KFM04251.1 - 5e-58 196.2 0.0 6.2e-58 195.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM04251.1 - 4.6e-38 130.7 0.0 8.6e-38 129.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase TGF_beta_GS PF08515.7 KFM04251.1 - 7.5e-14 50.7 0.0 1.5e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif APH PF01636.18 KFM04251.1 - 0.019 14.7 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ank_2 PF12796.2 KFM04252.1 - 3.1e-18 65.8 0.1 1e-09 38.5 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFM04252.1 - 6.7e-17 60.3 1.6 1.9e-06 27.4 0.1 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 KFM04252.1 - 1.2e-15 57.1 1.3 2.9e-07 30.5 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFM04252.1 - 2.1e-15 56.7 0.1 1.9e-06 28.2 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM04252.1 - 7.3e-14 50.4 0.3 1.5e-05 24.7 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat CENP-F_C_Rb_bdg PF10490.4 KFM04252.1 - 0.062 12.6 0.0 1.8 7.9 0.0 2.5 2 0 0 2 2 2 0 Rb-binding domain of kinetochore protein Cenp-F/LEK1 Plasmid_RAQPRD PF09686.5 KFM04253.1 - 0.055 13.5 0.0 0.076 13.1 0.0 1.2 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Methyltransf_11 PF08241.7 KFM04254.1 - 7.5e-15 55.2 0.0 1.1e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFM04254.1 - 2.1e-10 40.5 0.0 2.8e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFM04254.1 - 4.5e-10 39.8 0.0 9.8e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFM04254.1 - 2.8e-07 30.2 0.0 4.7e-07 29.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFM04254.1 - 4.6e-07 29.1 0.0 5.8e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.10 KFM04254.1 - 1.4e-05 24.8 0.0 2.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_25 PF13649.1 KFM04254.1 - 5.1e-05 23.5 0.0 8.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFM04254.1 - 9.7e-05 22.9 0.0 0.00016 22.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFM04254.1 - 0.006 16.6 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Apc4 PF12896.2 KFM04254.1 - 0.039 13.2 0.0 0.065 12.5 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 MetW PF07021.7 KFM04254.1 - 0.073 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_11 PF08241.7 KFM04255.1 - 6.6e-16 58.5 0.0 1e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFM04255.1 - 1.9e-13 50.4 0.0 2.4e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFM04255.1 - 2.1e-10 40.9 0.0 3.9e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFM04255.1 - 9.6e-09 35.0 0.0 1.3e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFM04255.1 - 8.3e-08 31.6 0.0 1e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KFM04255.1 - 1.4e-05 25.5 0.0 3.2e-05 24.4 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFM04255.1 - 3.8e-05 23.9 0.0 9.8e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFM04255.1 - 5.5e-05 23.1 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KFM04255.1 - 0.00054 19.6 0.0 0.00078 19.1 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase MetW PF07021.7 KFM04255.1 - 0.013 14.8 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_16 PF10294.4 KFM04255.1 - 0.026 13.9 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_29 PF03141.11 KFM04255.1 - 0.041 12.2 0.1 0.052 11.8 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Reovirus_L2 PF06016.6 KFM04255.1 - 0.16 8.9 0.0 0.19 8.6 0.0 1.1 1 0 0 1 1 1 0 Reovirus core-spike protein lambda-2 (L2) Trypsin PF00089.21 KFM04256.1 - 1.2e-69 234.2 0.1 1.3e-69 234.1 0.1 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 KFM04256.1 - 8.6e-05 21.9 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 KFM04256.1 - 0.0061 16.5 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain bZIP_1 PF00170.16 KFM04257.1 - 2.9e-22 78.3 8.7 4.7e-22 77.7 6.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor pKID PF02173.12 KFM04257.1 - 3e-17 61.5 5.7 3e-17 61.5 3.9 2.3 2 0 0 2 2 2 1 pKID domain bZIP_2 PF07716.10 KFM04257.1 - 5.2e-09 35.7 8.1 9.5e-09 34.9 5.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KFM04257.1 - 0.00019 21.6 4.8 0.00052 20.2 3.4 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor Acatn PF13000.2 KFM04257.1 - 0.046 12.2 0.8 0.063 11.7 0.6 1.1 1 0 0 1 1 1 0 Acetyl-coenzyme A transporter 1 La PF05383.12 KFM04258.1 - 3.3e-21 74.8 0.1 5.9e-21 74.0 0.1 1.4 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 KFM04258.1 - 0.00017 21.5 0.0 0.00056 19.8 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM04258.1 - 0.053 13.3 0.1 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LIM PF00412.17 KFM04259.1 - 2.3e-14 53.1 3.9 2.9e-14 52.8 2.7 1.1 1 0 0 1 1 1 1 LIM domain FANCL_C PF11793.3 KFM04259.1 - 0.057 13.3 1.1 0.1 12.5 0.8 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain DUF164 PF02591.10 KFM04259.1 - 0.15 11.8 3.2 0.4 10.5 0.2 2.2 1 1 1 2 2 2 0 Putative zinc ribbon domain zf-FCS PF06467.9 KFM04259.1 - 0.2 11.3 4.2 0.85 9.3 0.8 2.4 2 1 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif C1_4 PF07975.7 KFM04259.1 - 0.7 9.9 5.4 0.28 11.2 2.0 1.6 2 0 0 2 2 2 0 TFIIH C1-like domain Fer4_4 PF12800.2 KFM04259.1 - 4.6 7.8 7.0 9 6.9 1.1 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain TRAM_LAG1_CLN8 PF03798.11 KFM04260.1 - 3.4e-38 131.1 28.5 4e-38 130.9 19.7 1.0 1 0 0 1 1 1 1 TLC domain Homeobox PF00046.24 KFM04260.1 - 2.3e-07 30.3 0.2 4.1e-07 29.5 0.1 1.4 1 0 0 1 1 1 1 Homeobox domain NAD_Gly3P_dh_N PF01210.18 KFM04261.1 - 7e-57 191.5 0.5 1.3e-56 190.6 0.1 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 KFM04261.1 - 3.8e-56 188.9 0.2 5.9e-56 188.3 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 KFM04261.1 - 0.00031 21.0 2.9 0.013 15.9 0.2 3.3 3 1 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent SWIB PF02201.13 KFM04262.1 - 2.2e-26 91.3 0.1 6.9e-26 89.7 0.1 1.9 1 0 0 1 1 1 1 SWIB/MDM2 domain SusD PF07980.6 KFM04262.1 - 0.079 12.4 0.7 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 SusD family ASC PF00858.19 KFM04263.1 - 2.6e-178 593.2 0.0 3e-178 592.9 0.0 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel ASC PF00858.19 KFM04264.1 - 2.9e-37 128.3 0.1 3.2e-37 128.2 0.1 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel RhoGAP PF00620.22 KFM04265.1 - 2.2e-44 150.7 0.0 4.6e-44 149.7 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.17 KFM04265.1 - 2.9e-07 30.1 3.3 5.4e-07 29.2 2.3 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) TonB_2 PF13103.1 KFM04265.1 - 0.0035 17.3 0.1 0.011 15.6 0.0 1.8 1 0 0 1 1 1 1 TonB C terminal DUF2968 PF11180.3 KFM04265.1 - 0.0037 16.6 7.3 0.0063 15.9 5.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) V_ATPase_I PF01496.14 KFM04265.1 - 0.31 8.8 2.4 0.42 8.4 1.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prok-RING_1 PF14446.1 KFM04265.1 - 0.7 9.6 5.2 1.6 8.4 3.6 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 IncA PF04156.9 KFM04265.1 - 1.7 8.2 12.3 31 4.0 0.0 2.3 2 0 0 2 2 2 0 IncA protein HLH PF00010.21 KFM04266.1 - 3e-18 65.2 0.4 5.1e-18 64.5 0.2 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Toxin_trans PF07952.7 KFM04266.1 - 0.016 14.1 0.0 0.019 13.8 0.0 1.1 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain DUF773 PF05600.7 KFM04266.1 - 0.069 11.9 0.1 0.082 11.6 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF773) KbaA PF14089.1 KFM04267.1 - 0.095 12.2 3.2 0.078 12.5 1.5 1.3 1 1 0 1 1 1 0 KinB-signalling pathway activation in sporulation Claudin_2 PF13903.1 KFM04267.1 - 0.81 9.3 9.2 0.69 9.5 2.6 2.0 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction RasGEF PF00617.14 KFM04268.1 - 2.7e-62 209.8 0.7 4.2e-62 209.2 0.5 1.3 1 0 0 1 1 1 1 RasGEF domain DEP PF00610.16 KFM04268.1 - 2.9e-19 68.5 0.3 6.4e-19 67.4 0.2 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) cNMP_binding PF00027.24 KFM04268.1 - 1.1e-16 60.4 0.0 2.2e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain MutL PF13941.1 KFM04268.1 - 0.039 12.2 0.0 0.059 11.6 0.0 1.2 1 0 0 1 1 1 0 MutL protein MutL_C PF08676.6 KFM04268.1 - 0.099 12.2 0.1 0.21 11.1 0.1 1.6 1 0 0 1 1 1 0 MutL C terminal dimerisation domain XendoU PF09412.5 KFM04269.1 - 6.7e-95 317.1 0.1 7.8e-95 316.9 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU Somatomedin_B PF01033.12 KFM04269.1 - 3e-10 39.9 18.5 4.7e-10 39.2 12.8 1.3 1 0 0 1 1 1 1 Somatomedin B domain EndoU_bacteria PF14436.1 KFM04269.1 - 0.00079 19.2 0.3 0.0014 18.4 0.2 1.4 1 0 0 1 1 1 1 Bacterial EndoU nuclease Nckap1 PF09735.4 KFM04271.1 - 0 1350.0 0.2 0 1349.2 0.1 1.4 1 1 0 1 1 1 1 Membrane-associated apoptosis protein Hairy_orange PF07527.8 KFM04271.1 - 0.049 13.3 0.2 3.4 7.4 0.0 3.3 3 0 0 3 3 3 0 Hairy Orange 7tm_1 PF00001.16 KFM04272.1 - 7.8e-103 343.0 10.2 1.2e-102 342.4 7.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM04272.1 - 6.5e-18 64.8 22.0 1.8e-13 50.2 10.3 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 KFM04272.1 - 8.9e-06 25.0 24.4 0.0015 17.7 12.2 2.3 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv Rifin_STEVOR PF02009.11 KFM04272.1 - 0.018 14.7 0.6 0.018 14.7 0.4 1.9 2 1 0 2 2 2 0 Rifin/stevor family TMEM154 PF15102.1 KFM04272.1 - 0.055 13.1 0.2 0.055 13.1 0.2 3.2 2 1 1 3 3 3 0 TMEM154 protein family DUF3806 PF12713.2 KFM04272.1 - 0.069 12.6 0.4 16 5.0 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3806) DUF912 PF06024.7 KFM04272.1 - 1.9 8.5 11.7 3.5 7.7 0.5 4.0 4 1 1 5 5 5 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Zw10 PF06248.8 KFM04273.1 - 2.2e-233 775.7 17.3 2.7e-233 775.4 12.0 1.1 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Flagellin_C PF00700.16 KFM04273.1 - 0.013 15.6 4.1 0.015 15.4 0.2 2.9 2 1 0 2 2 2 0 Bacterial flagellin C-terminal helical region ITAM PF02189.10 KFM04274.1 - 1e-05 25.4 0.5 2e-05 24.5 0.4 1.5 1 0 0 1 1 1 1 Immunoreceptor tyrosine-based activation motif DAP10 PF07213.6 KFM04274.1 - 0.0086 15.8 0.1 0.015 14.9 0.1 1.4 1 0 0 1 1 1 1 DAP10 membrane protein ITAM PF02189.10 KFM04275.1 - 0.00052 20.1 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 Immunoreceptor tyrosine-based activation motif Ig_2 PF13895.1 KFM04275.1 - 0.004 17.2 0.3 0.0082 16.2 0.2 1.5 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFM04275.1 - 0.02 14.9 0.5 0.041 14.0 0.1 1.6 1 1 1 2 2 2 0 Immunoglobulin domain V-set PF07686.12 KFM04275.1 - 0.054 13.3 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin V-set domain V-set PF07686.12 KFM04276.1 - 1.3e-19 70.2 0.1 2.3e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 KFM04276.1 - 3.4e-06 26.8 0.2 8.5e-06 25.5 0.0 1.8 2 1 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM04276.1 - 8.3e-06 25.8 0.0 1.6e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFM04276.1 - 9.7e-05 22.4 0.7 0.0012 18.9 0.5 2.3 1 1 0 1 1 1 1 Immunoglobulin domain EphA2_TM PF14575.1 KFM04276.1 - 0.0026 18.1 0.3 0.0044 17.3 0.2 1.3 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 KFM04276.1 - 0.0035 17.0 1.0 0.0039 16.8 0.1 1.5 2 0 0 2 2 2 1 TMEM154 protein family Ig_3 PF13927.1 KFM04276.1 - 0.017 15.6 3.0 0.24 11.9 2.1 2.2 1 1 0 1 1 1 0 Immunoglobulin domain DUF3169 PF11368.3 KFM04276.1 - 0.017 14.3 0.1 0.022 13.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Shisa PF13908.1 KFM04276.1 - 0.018 15.2 0.3 0.026 14.6 0.2 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF3481 PF11980.3 KFM04276.1 - 0.021 14.6 0.1 0.046 13.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) Rifin_STEVOR PF02009.11 KFM04276.1 - 0.028 14.0 0.7 0.04 13.5 0.5 1.2 1 0 0 1 1 1 0 Rifin/stevor family Rax2 PF12768.2 KFM04276.1 - 0.029 13.6 0.1 0.047 12.9 0.1 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity ASFV_J13L PF05568.6 KFM04276.1 - 0.071 12.6 0.2 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein MLANA PF14991.1 KFM04276.1 - 0.074 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein melan-A Protocadherin PF08374.6 KFM04276.1 - 0.079 12.5 1.7 0.076 12.6 0.4 1.5 2 0 0 2 2 2 0 Protocadherin Peptidase_S49_N PF08496.5 KFM04276.1 - 0.092 12.5 0.3 0.15 11.8 0.2 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1510 PF07423.6 KFM04276.1 - 0.096 12.0 0.2 0.13 11.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TMEM51 PF15345.1 KFM04276.1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 DAP10 PF07213.6 KFM04276.1 - 0.13 12.0 0.3 0.22 11.2 0.2 1.3 1 0 0 1 1 1 0 DAP10 membrane protein Herpes_gE PF02480.11 KFM04276.1 - 0.27 9.4 1.4 2.3 6.3 1.1 1.9 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E Vpu PF00558.14 KFM04276.1 - 3.7 7.1 9.8 0.13 11.8 2.5 1.8 2 1 0 2 2 1 0 Vpu protein V-set PF07686.12 KFM04277.1 - 3.9e-14 52.5 0.0 5.6e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 KFM04277.1 - 0.0027 17.7 0.0 0.0067 16.5 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFM04277.1 - 0.0031 18.0 0.9 0.24 11.9 0.6 2.6 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFM04277.1 - 0.033 14.3 1.2 0.083 13.0 0.2 2.1 2 1 0 2 2 2 0 Immunoglobulin domain I-set PF07679.11 KFM04277.1 - 0.052 13.4 0.0 0.15 11.9 0.0 1.7 1 1 0 1 1 1 0 Immunoglobulin I-set domain V-set PF07686.12 KFM04279.1 - 1.8e-09 37.4 0.0 2.6e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain Herpes_gE PF02480.11 KFM04279.1 - 0.00095 17.5 0.0 0.23 9.6 0.0 2.0 1 1 1 2 2 2 2 Alphaherpesvirus glycoprotein E ig PF00047.20 KFM04279.1 - 0.0019 18.2 0.0 0.0042 17.1 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFM04280.1 - 1.5e-18 66.7 0.2 2.3e-18 66.1 0.2 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 KFM04280.1 - 1.1e-06 28.3 0.0 3.4e-06 26.8 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM04280.1 - 6.9e-06 26.0 0.2 1.1e-05 25.4 0.2 1.3 1 0 0 1 1 1 1 Immunoglobulin domain DUF1191 PF06697.7 KFM04280.1 - 5.1e-05 22.2 0.0 7.2e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) ig PF00047.20 KFM04280.1 - 6.5e-05 22.9 3.4 0.0011 18.9 2.3 2.4 1 1 0 1 1 1 1 Immunoglobulin domain PALP PF00291.20 KFM04280.1 - 0.0007 18.9 0.0 0.001 18.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme EphA2_TM PF14575.1 KFM04280.1 - 0.0023 18.2 0.0 0.0041 17.4 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.10 KFM04280.1 - 0.0028 17.1 0.4 0.0052 16.2 0.3 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Syndecan PF01034.15 KFM04280.1 - 0.0048 16.5 2.3 0.0081 15.7 0.0 2.5 4 0 0 4 4 4 1 Syndecan domain Herpes_gE PF02480.11 KFM04280.1 - 0.0056 15.0 0.7 0.25 9.5 0.2 2.2 1 1 1 2 2 2 2 Alphaherpesvirus glycoprotein E Protocadherin PF08374.6 KFM04280.1 - 0.011 15.3 0.1 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Protocadherin Ig_3 PF13927.1 KFM04280.1 - 0.015 15.7 3.7 0.049 14.1 2.6 1.9 1 1 0 1 1 1 0 Immunoglobulin domain Shisa PF13908.1 KFM04280.1 - 0.037 14.2 0.0 0.065 13.4 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Vpu PF00558.14 KFM04280.1 - 0.049 13.1 0.0 0.12 11.9 0.0 1.6 2 0 0 2 2 2 0 Vpu protein Mid2 PF04478.7 KFM04280.1 - 0.05 13.0 0.0 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor SKG6 PF08693.5 KFM04280.1 - 0.077 12.3 1.6 0.15 11.4 1.1 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain IncA PF04156.9 KFM04280.1 - 0.13 11.8 0.0 0.57 9.7 0.0 1.8 2 0 0 2 2 2 0 IncA protein V-set PF07686.12 KFM04281.1 - 6e-09 35.7 0.1 1.1e-08 34.9 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 KFM04281.1 - 4.2e-08 33.1 0.1 7.8e-08 32.3 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 KFM04281.1 - 1.6e-06 27.8 0.0 6.7e-06 25.8 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 KFM04281.1 - 8.8e-05 22.5 0.8 0.00054 20.0 0.6 2.3 1 1 0 1 1 1 1 Immunoglobulin domain V-set_CD47 PF08204.6 KFM04281.1 - 0.00028 20.6 0.8 0.00049 19.8 0.5 1.4 1 0 0 1 1 1 1 CD47 immunoglobulin-like domain Ig_3 PF13927.1 KFM04281.1 - 0.0017 18.7 0.6 0.005 17.3 0.4 1.9 1 1 0 1 1 1 1 Immunoglobulin domain Herpes_gE PF02480.11 KFM04281.1 - 0.012 13.9 1.3 0.015 13.6 0.1 1.6 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E Glycophorin_A PF01102.13 KFM04281.1 - 0.017 14.8 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A Tmemb_9 PF05434.6 KFM04281.1 - 0.031 14.0 0.1 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 TMEM9 TMEM154 PF15102.1 KFM04281.1 - 0.12 12.0 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Tissue_fac PF01108.12 KFM04282.1 - 1.4e-26 92.3 0.4 3.8e-26 90.9 0.0 2.0 2 0 0 2 2 2 1 Tissue factor Interfer-bind PF09294.5 KFM04282.1 - 1.5e-07 31.3 0.6 3.6e-07 30.1 0.4 1.6 1 0 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.16 KFM04282.1 - 6.2e-05 23.0 2.1 0.0053 16.8 0.1 2.6 2 0 0 2 2 2 2 Fibronectin type III domain ATP1G1_PLM_MAT8 PF02038.11 KFM04283.1 - 4e-28 96.1 0.0 4.7e-28 95.9 0.0 1.1 1 0 0 1 1 1 1 ATP1G1/PLM/MAT8 family DUF2367 PF10164.4 KFM04283.1 - 0.081 12.7 0.2 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) OSTbeta PF15048.1 KFM04283.1 - 0.097 12.7 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Ig_2 PF13895.1 KFM04284.1 - 9.7e-05 22.4 0.0 0.0053 16.8 0.0 2.5 2 1 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.1 KFM04284.1 - 0.00046 20.6 0.5 0.0011 19.4 0.1 1.8 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.11 KFM04284.1 - 0.011 15.6 0.0 0.2 11.5 0.0 2.6 2 1 0 2 2 2 0 Immunoglobulin I-set domain DUF2756 PF10956.3 KFM04285.1 - 0.044 14.0 3.8 0.19 12.0 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2756) KH_1 PF00013.24 KFM04285.1 - 0.11 12.1 0.0 0.42 10.2 0.0 1.9 2 0 0 2 2 2 0 KH domain Ras PF00071.17 KFM04286.1 - 9.1e-44 148.6 0.0 1.1e-43 148.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM04286.1 - 3.6e-11 43.5 0.0 5.6e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KFM04286.1 - 5.7e-05 22.6 0.0 7.2e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 KFM04286.1 - 0.00013 21.2 0.0 0.00016 21.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family C2 PF00168.25 KFM04287.1 - 4.6e-46 154.5 0.3 2.6e-22 78.4 0.0 2.4 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.1 KFM04287.1 - 0.0039 16.7 0.0 0.78 9.2 0.0 2.5 2 1 0 2 2 2 2 CEP76 C2 domain PTEN_C2 PF10409.4 KFM04287.1 - 0.032 13.9 0.1 0.069 12.8 0.1 1.5 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein PAH PF02671.16 KFM04288.1 - 1.9e-10 40.2 4.1 8.4e-05 22.1 0.0 3.4 4 0 0 4 4 4 2 Paired amphipathic helix repeat Myb_DNA-bind_6 PF13921.1 KFM04288.1 - 6.9e-05 22.8 0.1 0.0094 16.0 0.0 3.8 3 0 0 3 3 3 1 Myb-like DNA-binding domain Tubulin_3 PF14881.1 KFM04289.1 - 5.8e-24 84.5 0.0 8.9e-24 83.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.20 KFM04289.1 - 1.6e-09 37.8 0.0 2.5e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain DAP3 PF10236.4 KFM04290.1 - 1.3e-73 247.6 0.0 1.8e-73 247.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_19 PF13245.1 KFM04290.1 - 0.00099 18.8 0.0 0.0024 17.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KFM04290.1 - 0.0027 17.7 0.0 0.0043 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ResIII PF04851.10 KFM04290.1 - 0.017 14.9 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_25 PF13481.1 KFM04290.1 - 0.019 14.4 0.0 0.041 13.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KFM04290.1 - 0.021 14.9 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KFM04290.1 - 0.028 14.1 0.0 0.058 13.0 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase Fmp27_SW PF10305.4 KFM04290.1 - 0.028 14.8 1.2 0.078 13.4 0.5 2.0 2 1 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain NACHT PF05729.7 KFM04290.1 - 0.029 14.0 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain MobB PF03205.9 KFM04290.1 - 0.041 13.5 0.0 0.077 12.7 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 KFM04290.1 - 0.069 12.7 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KFM04290.1 - 0.096 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA PF00004.24 KFM04290.1 - 0.13 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RUN PF02759.14 KFM04291.1 - 2.9e-20 72.3 0.0 6.1e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 RUN domain SH3_1 PF00018.23 KFM04291.1 - 9.1e-10 37.7 0.0 2e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFM04291.1 - 4.5e-09 35.6 0.1 2.1e-08 33.5 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 KFM04291.1 - 2.1e-08 33.6 0.0 6.1e-08 32.1 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain polyprenyl_synt PF00348.12 KFM04292.1 - 1.5e-73 246.8 0.0 1.8e-73 246.6 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Erythro_esteras PF05139.9 KFM04292.1 - 0.0064 15.7 0.0 0.0098 15.1 0.0 1.2 1 0 0 1 1 1 1 Erythromycin esterase Annexin PF00191.15 KFM04292.1 - 0.085 12.7 0.1 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 Annexin DUF148 PF02520.12 KFM04292.1 - 0.11 12.3 0.1 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF148 cNMP_binding PF00027.24 KFM04293.1 - 6.3e-21 73.9 0.0 1.2e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.26 KFM04293.1 - 2.5e-19 69.3 10.1 8.1e-19 67.6 7.0 1.8 1 1 0 1 1 1 1 Ion transport protein Ion_trans_N PF08412.5 KFM04293.1 - 1.7e-13 49.7 0.6 1.7e-13 49.7 0.4 2.2 2 0 0 2 2 2 1 Ion transport protein N-terminal Ion_trans_2 PF07885.11 KFM04293.1 - 5.3e-05 22.8 0.4 0.00014 21.4 0.1 2.0 2 0 0 2 2 2 1 Ion channel Pkinase PF00069.20 KFM04294.1 - 9.9e-64 214.9 0.2 1.4e-63 214.4 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM04294.1 - 1.9e-21 76.3 0.1 8e-21 74.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Auxin_inducible PF02519.9 KFM04294.1 - 6.7 6.8 8.4 0.35 10.9 0.2 2.7 3 0 0 3 3 3 0 Auxin responsive protein CD20 PF04103.10 KFM04295.1 - 2.1e-27 95.8 13.0 2.8e-27 95.5 9.0 1.1 1 0 0 1 1 1 1 CD20-like family UPF0139 PF03669.8 KFM04295.1 - 1.2 8.6 5.5 0.32 10.5 0.1 2.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0139) DUF1049 PF06305.6 KFM04295.1 - 2.8 7.4 8.4 1.3 8.5 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Glyco_hydro_30 PF02055.11 KFM04296.1 - 2.8e-170 566.7 0.3 3.2e-170 566.5 0.2 1.0 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 DUF229 PF02995.12 KFM04296.1 - 0.17 10.2 0.0 0.24 9.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Glyco_hydro_30 PF02055.11 KFM04297.1 - 7.5e-186 618.1 0.0 8.3e-186 617.9 0.0 1.0 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 DUF229 PF02995.12 KFM04297.1 - 0.12 10.8 0.0 0.17 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Glyco_hydro_30 PF02055.11 KFM04299.1 - 2.7e-56 190.8 0.0 3.1e-56 190.6 0.0 1.0 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydro_30 PF02055.11 KFM04300.1 - 1.4e-83 280.8 0.0 1.5e-83 280.6 0.0 1.0 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 DUF229 PF02995.12 KFM04300.1 - 0.17 10.2 0.0 0.21 9.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) TSP_C PF05735.7 KFM04301.1 - 2.8e-77 258.8 1.9 3.9e-77 258.4 1.3 1.2 1 0 0 1 1 1 1 Thrombospondin C-terminal region TSP_3 PF02412.13 KFM04301.1 - 1.8e-61 203.3 133.0 1.2e-14 53.4 7.1 9.6 7 2 1 8 8 8 7 Thrombospondin type 3 repeat COMP PF11598.3 KFM04301.1 - 3.3e-22 78.2 3.7 5.9e-22 77.4 2.6 1.4 1 0 0 1 1 1 1 Cartilage oligomeric matrix protein EGF_CA PF07645.10 KFM04301.1 - 3e-12 46.3 21.4 1.5e-07 31.3 1.5 5.6 5 0 0 5 5 5 2 Calcium-binding EGF domain cEGF PF12662.2 KFM04301.1 - 4.1e-08 32.7 29.9 3.1e-05 23.4 0.7 5.3 4 0 0 4 4 4 2 Complement Clr-like EGF-like EGF_3 PF12947.2 KFM04301.1 - 5.3e-06 26.2 6.2 5.3e-06 26.2 4.3 6.4 4 3 0 5 5 5 3 EGF domain EGF PF00008.22 KFM04301.1 - 0.0026 17.7 6.2 0.0026 17.7 4.3 5.1 4 0 0 4 4 4 1 EGF-like domain Laminin_G_2 PF02210.19 KFM04301.1 - 0.021 14.8 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Laminin G domain EGF_MSP1_1 PF12946.2 KFM04301.1 - 0.094 12.5 19.7 0.036 13.8 3.8 3.2 2 0 0 2 2 2 0 MSP1 EGF domain 1 Herpes_gE PF02480.11 KFM04302.1 - 0.036 12.3 0.0 0.039 12.2 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SIT PF15330.1 KFM04302.1 - 0.04 14.0 0.0 0.043 13.9 0.0 1.2 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT LAT PF15234.1 KFM04302.1 - 0.041 13.3 0.2 0.042 13.3 0.2 1.1 1 0 0 1 1 1 0 Linker for activation of T-cells EphA2_TM PF14575.1 KFM04302.1 - 0.054 13.8 0.0 0.062 13.7 0.0 1.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM52 PF14979.1 KFM04302.1 - 0.064 13.1 1.1 0.07 13.0 0.7 1.2 1 0 0 1 1 1 0 Transmembrane 52 DUF3328 PF11807.3 KFM04302.1 - 0.065 12.8 0.0 0.082 12.5 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) Corona_S2 PF01601.11 KFM04302.1 - 0.086 10.9 0.2 0.09 10.8 0.1 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Chordopox_A33R PF05966.7 KFM04302.1 - 0.12 11.1 0.0 0.13 11.0 0.0 1.0 1 0 0 1 1 1 0 Chordopoxvirus A33R protein zf-B_box PF00643.19 KFM04303.1 - 3.1e-09 36.5 6.9 3.1e-09 36.5 4.8 4.8 5 1 0 5 5 5 2 B-box zinc finger fn3 PF00041.16 KFM04303.1 - 1e-05 25.5 0.0 1.9e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III domain SPRY PF00622.23 KFM04303.1 - 3.7e-05 23.8 0.0 9.9e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 SPRY domain zf-C3HC4 PF00097.20 KFM04303.1 - 6.3e-05 22.5 9.0 6.3e-05 22.5 6.3 4.0 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM04303.1 - 0.0008 19.3 9.3 0.0008 19.3 6.5 4.1 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFM04303.1 - 0.0032 17.3 10.5 0.0032 17.3 7.3 4.4 5 0 0 5 5 5 1 zinc finger of C3HC4-type, RING DUF2203 PF09969.4 KFM04303.1 - 0.076 13.2 2.6 1.3 9.2 0.0 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Tissue_fac PF01108.12 KFM04303.1 - 0.083 12.6 0.1 0.083 12.6 0.0 2.4 3 0 0 3 3 2 0 Tissue factor Baculo_PEP_C PF04513.7 KFM04303.1 - 0.1 12.4 1.5 0.21 11.4 1.0 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus V_ATPase_I PF01496.14 KFM04303.1 - 0.24 9.1 2.2 0.33 8.7 1.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HlyD PF00529.15 KFM04303.1 - 3.1 7.0 5.8 5.7 6.1 4.0 1.3 1 0 0 1 1 1 0 HlyD family secretion protein Keratin_assoc PF09775.4 KFM04304.1 - 1.6e-57 192.7 5.0 1.8e-57 192.5 3.5 1.0 1 0 0 1 1 1 1 Keratinocyte-associated protein 2 DUF4149 PF13664.1 KFM04304.1 - 5.7 7.0 9.6 63 3.7 6.6 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4149) I-set PF07679.11 KFM04305.1 - 0.00048 19.9 0.0 0.46 10.3 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.20 KFM04305.1 - 0.0051 16.9 0.2 3.7 7.7 0.1 3.0 3 1 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.1 KFM04305.1 - 0.0074 16.3 0.3 0.38 10.9 0.2 2.6 1 1 1 2 2 2 1 Immunoglobulin domain stn_TNFRSF12A PF12191.3 KFM04305.1 - 0.03 14.3 0.1 0.074 13.0 0.1 1.6 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain EphA2_TM PF14575.1 KFM04305.1 - 0.036 14.4 0.1 0.073 13.4 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Ig_3 PF13927.1 KFM04305.1 - 0.038 14.5 1.9 3.4 8.2 0.1 3.4 2 1 0 3 3 3 0 Immunoglobulin domain Orthoreo_P10 PF07204.6 KFM04305.1 - 0.056 13.1 1.0 0.11 12.1 0.7 1.5 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 DUF3481 PF11980.3 KFM04305.1 - 0.096 12.5 2.0 0.21 11.4 1.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) V-set PF07686.12 KFM04306.1 - 2.9e-05 23.9 0.1 4.4e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 KFM04306.1 - 4.5e-05 23.2 0.2 7.6e-05 22.4 0.2 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Herpes_gE PF02480.11 KFM04306.1 - 0.045 12.0 0.0 0.048 11.9 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E MORN_2 PF07661.8 KFM04306.1 - 0.14 12.2 0.8 1.2 9.4 0.0 2.6 3 0 0 3 3 3 0 MORN repeat variant Ig_3 PF13927.1 KFM04306.1 - 0.15 12.6 0.4 0.76 10.3 0.0 2.0 2 0 0 2 2 2 0 Immunoglobulin domain V-set PF07686.12 KFM04307.1 - 1.1e-25 89.7 14.5 3.5e-07 30.0 0.1 7.0 5 2 2 7 7 7 5 Immunoglobulin V-set domain Ig_2 PF13895.1 KFM04307.1 - 3e-22 78.5 7.2 1.5e-05 25.0 0.0 5.8 5 1 0 5 5 5 5 Immunoglobulin domain I-set PF07679.11 KFM04307.1 - 1e-20 73.3 3.3 0.00034 20.4 0.0 7.3 7 1 0 7 7 7 5 Immunoglobulin I-set domain ig PF00047.20 KFM04307.1 - 6.9e-15 54.9 12.3 0.00078 19.5 0.1 8.5 7 3 0 7 7 7 4 Immunoglobulin domain Ig_3 PF13927.1 KFM04307.1 - 3.9e-07 30.4 12.1 1.7 9.2 0.1 7.5 6 3 0 6 6 6 3 Immunoglobulin domain V-set PF07686.12 KFM04308.1 - 9.6e-62 205.9 1.4 1.2e-11 44.5 0.0 7.3 6 1 0 7 7 7 7 Immunoglobulin V-set domain I-set PF07679.11 KFM04308.1 - 8e-39 131.3 3.2 1.4e-05 24.8 0.0 10.6 7 6 0 7 7 7 7 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM04308.1 - 3.3e-33 113.6 5.0 4.3e-06 26.7 0.0 7.8 7 0 0 7 7 7 7 Immunoglobulin domain Ig_3 PF13927.1 KFM04308.1 - 2.8e-17 62.9 11.1 0.48 10.9 0.3 10.0 8 4 0 8 8 8 6 Immunoglobulin domain ig PF00047.20 KFM04308.1 - 1.1e-15 57.4 20.8 0.087 12.9 0.0 11.6 11 4 0 11 11 11 6 Immunoglobulin domain Transglut_N PF00868.15 KFM04308.1 - 0.0019 18.2 0.0 0.081 12.9 0.0 2.9 2 0 0 2 2 2 1 Transglutaminase family V-set PF07686.12 KFM04309.1 - 1.2e-60 202.3 10.4 2.9e-10 40.0 0.0 9.0 8 1 0 8 8 8 8 Immunoglobulin V-set domain I-set PF07679.11 KFM04309.1 - 7.6e-40 134.6 6.8 6.1e-05 22.8 0.0 11.4 8 5 0 8 8 8 8 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM04309.1 - 1.2e-30 105.4 3.8 0.0014 18.7 0.0 8.7 8 0 0 8 8 8 7 Immunoglobulin domain ig PF00047.20 KFM04309.1 - 4.6e-28 97.1 8.2 0.00059 19.9 0.0 11.7 10 4 0 10 10 10 7 Immunoglobulin domain Ig_3 PF13927.1 KFM04309.1 - 2.2e-13 50.4 22.9 1.7 9.2 0.3 11.8 8 6 1 9 9 9 5 Immunoglobulin domain DUF3821 PF12863.2 KFM04309.1 - 3.5e-07 30.1 0.4 0.25 10.9 0.0 4.5 4 0 0 4 4 4 2 Domain of unknown function (DUF3821) Herpes_gI PF01688.12 KFM04309.1 - 0.0012 18.0 0.0 23 4.0 0.0 5.1 5 0 0 5 5 5 0 Alphaherpesvirus glycoprotein I Receptor_2B4 PF11465.3 KFM04309.1 - 0.0015 18.3 0.0 9.5 6.1 0.0 5.4 6 0 0 6 6 6 1 Natural killer cell receptor 2B4 V-set PF07686.12 KFM04310.1 - 8.9e-10 38.4 0.4 2e-09 37.3 0.1 1.7 2 0 0 2 2 2 1 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM04310.1 - 2.8e-07 30.3 2.6 2.9e-07 30.2 0.8 1.8 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.1 KFM04310.1 - 1.9e-05 25.0 11.5 0.11 13.0 0.0 3.5 2 1 1 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.1 KFM04310.1 - 0.00052 20.0 4.5 0.38 10.9 0.0 3.2 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 KFM04310.1 - 0.0007 19.3 0.1 0.0029 17.4 0.0 2.1 2 1 0 2 2 2 1 Immunoglobulin I-set domain C1-set PF07654.10 KFM04310.1 - 0.013 15.5 4.0 0.5 10.4 0.3 2.8 2 2 0 2 2 2 0 Immunoglobulin C1-set domain ig PF00047.20 KFM04310.1 - 0.03 14.4 1.4 3.8 7.6 0.2 3.6 2 1 0 2 2 2 0 Immunoglobulin domain Tim17 PF02466.14 KFM04311.1 - 3.1e-11 43.3 1.2 4.1e-11 43.0 0.9 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Glyco_transf_90 PF05686.7 KFM04312.1 - 1.4e-113 379.6 0.8 1.7e-113 379.3 0.6 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 KFM04312.1 - 0.03 14.6 0.0 0.052 13.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 BCL9 PF11502.3 KFM04313.1 - 3.8e-22 77.5 2.0 1.7e-21 75.4 1.4 2.3 1 0 0 1 1 1 1 B-cell lymphoma 9 protein His_Phos_2 PF00328.17 KFM04314.1 - 3.8e-32 111.9 0.0 4.9e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Connexin PF00029.14 KFM04315.1 - 8.3e-53 176.9 0.3 1.8e-52 175.8 0.2 1.6 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 KFM04315.1 - 1.5e-29 101.5 3.1 3.4e-29 100.4 2.2 1.6 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain Adeno_E3_14_5 PF04834.7 KFM04315.1 - 0.035 14.5 0.2 0.6 10.5 0.0 2.5 2 0 0 2 2 2 0 Early E3 14.5 kDa protein LSR PF05624.9 KFM04315.1 - 1.3 8.7 5.0 0.52 10.0 0.2 2.6 2 0 0 2 2 2 0 Lipolysis stimulated receptor (LSR) Connexin PF00029.14 KFM04316.1 - 1.4e-52 176.2 0.3 1.4e-52 176.2 0.2 1.6 2 0 0 2 2 2 1 Connexin Connexin50 PF03509.9 KFM04316.1 - 9.8e-37 125.0 0.6 9.8e-37 125.0 0.4 2.2 2 0 0 2 2 2 1 Gap junction alpha-8 protein (Cx50) Connexin_CCC PF10582.4 KFM04316.1 - 3.2e-32 110.1 1.4 6.5e-32 109.1 1.0 1.6 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain ABA_GPCR PF12430.3 KFM04317.1 - 5.4e-62 208.4 14.2 5.4e-62 208.4 9.8 2.2 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 KFM04317.1 - 3.5e-28 97.4 0.1 1e-27 95.9 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3735) PDZ PF00595.19 KFM04318.1 - 1.2e-54 182.4 9.4 5.6e-13 48.8 0.1 4.2 4 0 0 4 4 4 4 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM04318.1 - 6.5e-34 115.6 10.0 3.3e-09 36.5 0.4 4.2 4 0 0 4 4 4 4 PDZ domain GRASP55_65 PF04495.9 KFM04318.1 - 1.2e-11 44.8 1.9 0.022 14.7 0.0 4.1 3 1 1 4 4 4 3 GRASP55/65 PDZ-like domain Tricorn_PDZ PF14685.1 KFM04318.1 - 1.3e-06 28.1 3.0 0.036 13.8 0.0 4.4 4 0 0 4 4 4 2 Tricorn protease PDZ domain DUF3394 PF11874.3 KFM04318.1 - 0.002 17.7 0.2 18 4.7 0.0 4.2 4 1 0 4 4 4 1 Domain of unknown function (DUF3394) DUF4265 PF14085.1 KFM04318.1 - 0.015 15.0 1.2 0.085 12.6 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4265) DUF1450 PF07293.6 KFM04318.1 - 0.19 11.7 3.2 27 4.8 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1450) 7tm_1 PF00001.16 KFM04319.1 - 1.2e-80 270.3 10.7 1.6e-80 270.0 7.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 KFM04319.1 - 1.9e-08 33.7 10.8 0.00039 19.6 5.3 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.4 KFM04319.1 - 9.9e-08 31.4 16.3 5e-07 29.1 11.3 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM04319.1 - 0.00043 19.4 12.8 0.00043 19.4 8.8 2.4 2 2 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Pou PF00157.12 KFM04320.1 - 1.4e-36 123.9 1.6 1.8e-36 123.6 0.2 1.9 2 0 0 2 2 2 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.24 KFM04320.1 - 2.1e-17 62.5 1.8 2.1e-17 62.5 1.3 1.7 2 0 0 2 2 2 1 Homeobox domain Lsr2 PF11774.3 KFM04320.1 - 0.015 15.1 0.2 0.031 14.1 0.1 1.5 1 0 0 1 1 1 0 Lsr2 Snf7 PF03357.16 KFM04321.1 - 1.2e-43 148.4 29.2 1.2e-43 148.4 20.2 1.4 2 0 0 2 2 2 1 Snf7 DUF3947 PF13135.1 KFM04321.1 - 0.11 12.6 2.9 0.22 11.7 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) CDC37_N PF03234.9 KFM04321.1 - 0.3 11.3 17.8 0.51 10.6 12.3 1.4 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding DnaJ-X PF14308.1 KFM04321.1 - 0.52 9.5 19.0 0.055 12.7 9.8 1.8 1 1 1 2 2 2 0 X-domain of DnaJ-containing Peptidase_S46 PF10459.4 KFM04321.1 - 0.97 7.7 13.5 1.1 7.6 9.4 1.1 1 0 0 1 1 1 0 Peptidase S46 CorA PF01544.13 KFM04321.1 - 1.8 7.5 7.9 12 4.8 5.4 2.0 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein SICA_beta PF12878.2 KFM04321.1 - 2.9 7.6 14.7 5.4 6.7 10.2 1.5 1 1 0 1 1 1 0 SICA extracellular beta domain DUF940 PF06082.6 KFM04321.1 - 4.4 5.7 8.5 5.5 5.4 5.9 1.1 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) DUF3573 PF12097.3 KFM04321.1 - 4.6 5.7 8.6 5.7 5.4 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) hDGE_amylase PF14701.1 KFM04321.1 - 7 5.4 12.4 11 4.7 8.6 1.4 1 1 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme SOBP PF15279.1 KFM04321.1 - 9.4 6.5 9.5 11 6.2 6.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Vg_Tdu PF07545.9 KFM04322.1 - 6.5e-21 73.4 0.4 1e-20 72.8 0.3 1.3 1 0 0 1 1 1 1 Vestigial/Tondu family FAM220 PF15487.1 KFM04322.1 - 0.11 11.8 1.8 0.18 11.1 1.2 1.3 1 1 0 1 1 1 0 FAM220 family I-set PF07679.11 KFM04324.1 - 1.2e-23 82.7 0.0 9.6e-11 41.4 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM04324.1 - 1.1e-22 79.9 0.0 9.9e-11 41.6 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 KFM04324.1 - 4.3e-19 68.7 0.2 4.3e-09 36.7 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain C2-set_2 PF08205.7 KFM04324.1 - 2.7e-17 62.4 5.0 6.7e-16 57.9 0.0 2.7 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain ig PF00047.20 KFM04324.1 - 2.6e-16 59.5 0.1 8.3e-08 32.2 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 KFM04324.1 - 1.9e-13 50.3 0.2 0.013 15.3 0.0 3.9 3 1 0 3 3 3 3 Immunoglobulin V-set domain C1-set PF07654.10 KFM04324.1 - 2.8e-10 40.0 0.4 1.5e-09 37.6 0.0 2.4 3 0 0 3 3 3 1 Immunoglobulin C1-set domain BPD_transp_1 PF00528.17 KFM04324.1 - 0.088 12.3 1.5 0.13 11.7 1.0 1.1 1 0 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component RVT_1 PF00078.22 KFM04325.1 - 0.017 14.4 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Alpha-amylase PF00128.19 KFM04326.1 - 1.5e-18 67.2 0.5 6.8e-16 58.5 0.1 2.8 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 KFM04326.1 - 1.7e-15 56.8 0.1 1.5e-14 53.9 0.1 2.3 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.13 KFM04326.1 - 5.5e-15 55.1 0.0 1.3e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) hDGE_amylase PF14701.1 KFM04326.1 - 0.031 13.2 0.1 0.072 11.9 0.0 1.5 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme RuBisCO_large PF00016.15 KFM04326.1 - 0.16 10.8 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Aminotran_5 PF00266.14 KFM04326.1 - 0.24 10.0 0.0 0.34 9.5 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-V I-set PF07679.11 KFM04327.1 - 8.1e-16 57.6 0.0 1.2e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM04327.1 - 2.7e-13 49.8 0.0 3.2e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFM04327.1 - 2e-09 37.7 0.0 3e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFM04327.1 - 1.5e-05 24.9 0.1 0.00016 21.7 0.1 2.1 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFM04327.1 - 7.3e-05 22.6 0.0 0.00026 20.8 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM04327.1 - 0.00025 20.8 0.0 0.00035 20.4 0.0 1.3 1 1 0 1 1 1 1 CD80-like C2-set immunoglobulin domain BiPBP_C PF06832.7 KFM04327.1 - 0.15 11.9 0.0 0.26 11.2 0.0 1.4 1 1 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family I-set PF07679.11 KFM04329.1 - 1.3e-72 239.6 0.0 7.4e-23 80.2 0.0 4.7 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM04329.1 - 2.4e-40 136.5 0.1 8.5e-09 35.4 0.0 4.8 4 0 0 4 4 4 4 Immunoglobulin domain fn3 PF00041.16 KFM04329.1 - 9.1e-34 115.4 10.1 1e-12 47.9 0.4 4.1 3 0 0 3 3 3 3 Fibronectin type III domain Ig_3 PF13927.1 KFM04329.1 - 1.1e-31 109.0 1.6 4.3e-08 33.5 0.2 6.1 6 0 0 6 6 6 4 Immunoglobulin domain ig PF00047.20 KFM04329.1 - 6.5e-26 90.2 0.8 5.2e-09 36.0 0.3 5.2 5 0 0 5 5 5 4 Immunoglobulin domain V-set PF07686.12 KFM04329.1 - 7.2e-25 87.1 2.2 9.3e-10 38.4 0.0 6.3 5 3 0 5 5 5 4 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM04329.1 - 2.7e-09 36.7 5.1 0.031 14.1 0.0 5.7 6 0 0 6 6 6 3 CD80-like C2-set immunoglobulin domain Big_4 PF07532.6 KFM04329.1 - 0.88 9.1 6.6 0.087 12.3 0.5 2.5 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 4) I-set PF07679.11 KFM04330.1 - 4.2e-74 244.4 0.0 4.9e-23 80.7 0.0 5.0 5 0 0 5 5 5 4 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM04330.1 - 1.7e-47 159.4 0.1 1.8e-11 43.9 0.0 4.7 4 0 0 4 4 4 4 Immunoglobulin domain Ig_3 PF13927.1 KFM04330.1 - 6.1e-38 129.1 1.4 9.5e-09 35.6 0.0 6.3 7 0 0 7 7 7 4 Immunoglobulin domain fn3 PF00041.16 KFM04330.1 - 1.1e-37 127.9 13.8 3.6e-15 55.8 0.7 4.4 4 0 0 4 4 4 3 Fibronectin type III domain ig PF00047.20 KFM04330.1 - 5.9e-33 112.7 0.1 2e-08 34.2 0.1 5.9 4 1 0 4 4 4 4 Immunoglobulin domain V-set PF07686.12 KFM04330.1 - 9.8e-32 109.2 1.5 6.3e-09 35.7 0.0 6.2 3 2 1 4 4 4 4 Immunoglobulin V-set domain Herpes_gE PF02480.11 KFM04330.1 - 0.00014 20.2 0.7 6.6 4.8 0.0 4.6 3 1 2 5 5 5 2 Alphaherpesvirus glycoprotein E Sp38 PF07354.7 KFM04330.1 - 0.0015 17.2 0.0 9.6 4.7 0.0 3.9 4 0 0 4 4 4 1 Zona-pellucida-binding protein (Sp38) Receptor_2B4 PF11465.3 KFM04330.1 - 0.0067 16.3 0.4 10 6.0 0.0 4.4 3 2 1 4 4 4 1 Natural killer cell receptor 2B4 C2-set PF05790.10 KFM04330.1 - 0.051 13.5 0.0 13 5.8 0.0 3.8 3 0 0 3 3 3 0 Immunoglobulin C2-set domain RRN7 PF11781.3 KFM04330.1 - 0.52 9.8 2.7 16 5.1 0.1 3.6 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 I-set PF07679.11 KFM04331.1 - 3.2e-16 58.9 0.0 4.6e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM04331.1 - 7e-14 51.7 0.0 8.3e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFM04331.1 - 6.2e-09 36.2 0.0 1.2e-08 35.3 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFM04331.1 - 2.2e-05 24.4 0.1 0.00023 21.2 0.1 2.1 1 1 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.7 KFM04331.1 - 0.00015 21.6 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain V-set PF07686.12 KFM04331.1 - 0.00055 19.8 0.0 0.0019 18.0 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin V-set domain BiPBP_C PF06832.7 KFM04331.1 - 0.008 16.0 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Penicillin-Binding Protein C-terminus Family Lipase PF00151.14 KFM04332.1 - 1.6e-79 267.5 0.0 2.2e-79 267.0 0.0 1.1 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.2 KFM04332.1 - 7.7e-05 22.6 0.0 0.00012 22.0 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFM04332.1 - 0.02 14.6 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Mating_C PF12737.2 KFM04333.1 - 0.038 12.8 8.2 0.02 13.8 4.6 1.3 1 1 0 1 1 1 0 C-terminal domain of homeodomain 1 DUF2547 PF10818.3 KFM04333.1 - 0.12 12.9 1.8 3 8.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2547) HSP70 PF00012.15 KFM04334.1 - 3.6e-114 381.8 0.3 1.2e-81 274.4 0.0 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 KFM04334.1 - 1.7e-15 56.5 0.2 6.5e-11 41.3 0.0 3.0 2 1 0 3 3 3 2 MreB/Mbl protein StbA PF06406.6 KFM04334.1 - 0.0066 15.4 0.1 0.017 14.0 0.0 1.7 2 0 0 2 2 2 1 StbA protein BcrAD_BadFG PF01869.15 KFM04334.1 - 0.017 14.4 0.0 6.6 5.9 0.0 3.0 2 1 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family Flavodoxin_5 PF12724.2 KFM04334.1 - 0.026 14.5 0.1 2.1 8.3 0.0 2.3 2 0 0 2 2 2 0 Flavodoxin domain DDR PF08841.5 KFM04334.1 - 0.032 13.0 0.2 0.36 9.6 0.0 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 KFM04334.1 - 0.12 11.4 0.2 0.31 10.1 0.0 1.8 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase FtsA PF14450.1 KFM04334.1 - 1.1 9.0 6.0 60 3.5 0.1 3.9 4 1 0 4 4 4 0 Cell division protein FtsA SLY PF12485.3 KFM04335.1 - 2e-51 174.2 5.8 2e-51 174.2 4.0 1.9 2 0 0 2 2 2 1 Lymphocyte signaling adaptor protein SAM_2 PF07647.12 KFM04335.1 - 1.3e-09 37.7 0.2 2.8e-09 36.6 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFM04335.1 - 7.1e-08 32.5 0.1 1.7e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.12 KFM04335.1 - 8.6e-05 21.9 0.0 0.00017 21.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM04335.1 - 0.023 14.0 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 SH3 domain Hexokinase_1 PF00349.16 KFM04336.1 - 0.037 13.3 0.0 0.071 12.4 0.0 1.4 1 0 0 1 1 1 0 Hexokinase Lectin_C PF00059.16 KFM04337.1 - 0.0012 19.4 0.0 0.0026 18.3 0.0 1.6 1 0 0 1 1 1 1 Lectin C-type domain Herpes_UL45 PF05473.7 KFM04337.1 - 0.0014 18.0 0.3 0.0014 18.0 0.2 2.1 2 1 1 3 3 3 1 UL45 protein Chordopox_A33R PF05966.7 KFM04337.1 - 0.002 16.9 2.9 0.0098 14.6 2.0 2.0 1 1 0 1 1 1 1 Chordopoxvirus A33R protein Ion_trans PF00520.26 KFM04338.1 - 2.6e-30 105.1 4.9 6.7e-30 103.8 2.7 1.8 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 KFM04338.1 - 1.5e-15 57.1 1.0 5.3e-15 55.3 0.1 2.0 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans_2 PF07885.11 KFM04338.1 - 2.2e-12 46.5 7.3 2.2e-12 46.5 5.1 2.1 2 0 0 2 2 2 1 Ion channel PKD_channel PF08016.7 KFM04338.1 - 0.0015 17.0 1.7 0.0024 16.3 1.2 1.3 1 0 0 1 1 1 1 Polycystin cation channel DUF423 PF04241.10 KFM04338.1 - 0.32 10.9 3.2 0.14 12.1 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF423) Myosin_head PF00063.16 KFM04340.1 - 1.4e-213 710.8 3.3 1.6e-213 710.6 2.3 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.14 KFM04340.1 - 3e-14 52.4 0.7 8.2e-14 51.0 0.5 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain T2SE PF00437.15 KFM04340.1 - 0.0098 14.8 0.1 0.025 13.5 0.0 1.7 1 1 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 KFM04340.1 - 0.022 14.8 0.0 0.055 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KFM04340.1 - 0.03 14.2 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 KFM04340.1 - 0.07 12.6 0.0 0.38 10.3 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF4537 PF15057.1 KFM04340.1 - 0.081 12.7 0.4 0.82 9.4 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4537) AAA_19 PF13245.1 KFM04340.1 - 0.18 11.5 0.0 0.39 10.5 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain Ribosomal_L37e PF01907.14 KFM04342.1 - 7.9e-25 86.4 15.3 1.3e-24 85.7 10.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 KFM04342.1 - 0.0023 17.6 2.4 0.0037 17.0 1.7 1.3 1 0 0 1 1 1 1 Double zinc ribbon FeS PF04060.8 KFM04342.1 - 0.011 15.3 2.1 0.013 15.0 0.1 2.0 2 0 0 2 2 2 0 Putative Fe-S cluster zf-NADH-PPase PF09297.6 KFM04342.1 - 0.032 13.7 2.5 0.62 9.6 0.0 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain FYDLN_acid PF09538.5 KFM04342.1 - 0.16 12.5 1.4 0.16 12.5 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) GFA PF04828.9 KFM04342.1 - 0.34 10.8 4.1 0.88 9.5 0.3 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_S27 PF01599.14 KFM04342.1 - 0.79 9.5 5.9 1.8 8.4 4.1 1.6 1 0 0 1 1 1 0 Ribosomal protein S27a zinc_ribbon_2 PF13240.1 KFM04342.1 - 0.8 9.2 4.3 11 5.5 0.7 2.2 2 0 0 2 2 2 0 zinc-ribbon domain DUF2688 PF10892.3 KFM04342.1 - 1 9.0 3.5 6.3 6.5 2.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) MACPF PF01823.14 KFM04343.1 - 4e-46 157.3 0.2 4e-46 157.3 0.2 2.1 1 1 1 2 2 2 1 MAC/Perforin domain Sushi PF00084.15 KFM04343.1 - 3e-12 46.6 1.8 6.1e-09 36.1 0.3 4.2 4 0 0 4 4 4 2 Sushi domain (SCR repeat) Ldl_recept_a PF00057.13 KFM04343.1 - 1e-07 31.7 14.3 1e-07 31.7 9.9 4.6 4 0 0 4 4 4 1 Low-density lipoprotein receptor domain class A TSP_1 PF00090.14 KFM04343.1 - 7.6e-07 29.1 24.1 5.3e-05 23.2 2.6 6.0 5 1 1 6 6 6 2 Thrombospondin type 1 domain MACPF PF01823.14 KFM04344.1 - 9.6e-46 156.1 1.8 1.8e-45 155.2 1.1 1.5 2 0 0 2 2 2 1 MAC/Perforin domain Sushi PF00084.15 KFM04344.1 - 1.9e-12 47.3 5.7 4.5e-08 33.3 0.5 5.5 6 0 0 6 6 6 2 Sushi domain (SCR repeat) TSP_1 PF00090.14 KFM04344.1 - 3.8e-11 42.9 15.9 7.6e-07 29.1 6.2 6.1 5 0 0 5 5 5 3 Thrombospondin type 1 domain Ldl_recept_a PF00057.13 KFM04344.1 - 8.2e-11 41.6 14.4 8.2e-11 41.6 10.0 3.9 3 0 0 3 3 3 1 Low-density lipoprotein receptor domain class A PI-PLC-X PF00388.14 KFM04345.1 - 3.6e-07 29.6 0.0 5.5e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain CoA_trans PF01144.18 KFM04346.1 - 9.3e-125 413.9 1.5 3.2e-75 252.0 0.2 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 KFM04346.1 - 0.0014 18.3 0.1 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain F-box-like PF12937.2 KFM04348.1 - 2.9e-09 36.5 1.5 7.3e-09 35.2 1.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFM04348.1 - 8.8e-08 31.6 0.1 1.9e-07 30.5 0.1 1.6 1 0 0 1 1 1 1 F-box domain Arf PF00025.16 KFM04348.1 - 0.026 13.7 0.0 0.045 12.9 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family PRANC PF09372.5 KFM04348.1 - 0.033 14.1 0.0 0.11 12.5 0.0 1.9 1 0 0 1 1 1 0 PRANC domain GHBP PF12772.2 KFM04349.1 - 2.8e-107 358.5 10.9 3.7e-107 358.1 7.5 1.1 1 0 0 1 1 1 1 Growth hormone receptor binding EpoR_lig-bind PF09067.5 KFM04349.1 - 1.4e-12 47.4 2.9 1.4e-12 47.4 2.0 2.5 3 0 0 3 3 3 1 Erythropoietin receptor, ligand binding fn3 PF00041.16 KFM04349.1 - 8.7e-07 28.9 0.3 2e-06 27.8 0.2 1.6 1 0 0 1 1 1 1 Fibronectin type III domain IL6Ra-bind PF09240.5 KFM04349.1 - 0.017 15.3 0.9 0.056 13.6 0.7 1.9 1 0 0 1 1 1 0 Interleukin-6 receptor alpha chain, binding Pox_A_type_inc PF04508.7 KFM04350.1 - 0.043 13.6 1.4 0.043 13.6 1.0 5.1 4 2 1 5 5 5 0 Viral A-type inclusion protein repeat TSC22 PF01166.13 KFM04350.1 - 0.048 13.6 0.7 0.048 13.6 0.5 3.8 2 1 2 4 4 4 0 TSC-22/dip/bun family DUF885 PF05960.6 KFM04350.1 - 0.32 10.0 8.1 0.39 9.8 5.6 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) DUF4140 PF13600.1 KFM04350.1 - 1.5 9.2 10.1 0.23 11.9 2.2 2.6 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) SelP_N PF04592.9 KFM04351.1 - 1.3e-36 126.1 12.0 1.4e-36 126.0 8.3 1.0 1 0 0 1 1 1 1 Selenoprotein P, N terminal region Zip PF02535.17 KFM04351.1 - 0.13 11.2 7.4 0.12 11.3 5.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter BTB PF00651.26 KFM04352.1 - 1.7e-24 85.8 0.5 4.6e-24 84.5 0.3 1.8 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 KFM04352.1 - 1.1e-16 60.1 52.6 9.9e-08 31.9 4.5 7.6 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.21 KFM04352.1 - 6.5e-14 51.3 56.1 0.012 15.9 0.1 6.6 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM04352.1 - 2e-11 43.3 56.2 0.021 15.1 3.4 6.6 6 0 0 6 6 6 5 C2H2-type zinc finger zf-met PF12874.2 KFM04352.1 - 1.9e-06 27.8 5.5 0.00064 19.8 0.6 6.6 7 0 0 7 7 6 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFM04352.1 - 8.5e-06 25.7 43.5 0.00095 19.2 0.3 6.7 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding GAGA PF09237.6 KFM04352.1 - 0.011 15.3 1.8 2.1 8.0 0.0 3.7 3 0 0 3 3 3 0 GAGA factor zf-C2H2_6 PF13912.1 KFM04352.1 - 0.029 14.2 42.9 0.28 11.1 0.1 6.7 6 1 0 6 6 6 0 C2H2-type zinc finger zf-CHCC PF10276.4 KFM04352.1 - 0.83 9.5 8.4 0.6 10.0 0.2 3.8 4 0 0 4 4 4 0 Zinc-finger domain zf-C2H2_2 PF12756.2 KFM04352.1 - 3.3 7.8 36.4 3.7 7.6 1.5 6.5 2 2 3 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 KFM04352.1 - 3.8 7.2 20.4 0.38 10.4 0.6 4.8 5 0 0 5 5 5 0 zinc-finger of a C2HC-type Pkinase PF00069.20 KFM04353.1 - 6.4e-70 235.2 0.0 1e-69 234.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM04353.1 - 1.2e-39 135.9 0.0 1.7e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM04353.1 - 8.6e-10 38.0 0.0 1.3e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KFM04353.1 - 0.00024 20.5 0.1 0.00041 19.7 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KFM04353.1 - 0.0025 16.9 0.1 0.0058 15.7 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family HMG_CoA_synt_C PF08540.5 KFM04354.1 - 3.7e-128 426.9 0.5 4.6e-128 426.5 0.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KFM04354.1 - 3.5e-107 355.5 0.5 4.8e-107 355.0 0.3 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III PF08545.5 KFM04354.1 - 0.00025 20.6 0.1 0.00063 19.3 0.1 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF457 PF04307.9 KFM04355.1 - 0.00046 19.5 9.2 0.00069 18.9 6.4 1.3 1 0 0 1 1 1 1 Predicted membrane-bound metal-dependent hydrolase (DUF457) DUF4524 PF15025.1 KFM04356.1 - 9.5e-61 203.6 0.0 3.6e-58 195.2 0.0 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4524) DUF4520 PF15016.1 KFM04356.1 - 2.6e-29 100.6 0.0 4.1e-28 96.7 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4520) MIF4G PF02854.14 KFM04357.1 - 9.9e-29 100.2 0.2 1.2e-28 99.9 0.1 1.1 1 0 0 1 1 1 1 MIF4G domain PAM2 PF07145.10 KFM04357.1 - 0.0035 16.7 0.0 0.0074 15.7 0.0 1.5 1 0 0 1 1 1 1 Ataxin-2 C-terminal region DIT1_PvcA PF05141.7 KFM04357.1 - 0.071 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein PNTB PF02233.11 KFM04358.1 - 2.9e-212 705.5 17.0 2.9e-212 705.5 11.8 2.3 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 KFM04358.1 - 5.2e-53 179.0 1.2 9.8e-53 178.1 0.8 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 KFM04358.1 - 4.4e-46 156.2 0.8 1.7e-45 154.3 0.1 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 KFM04358.1 - 3.8e-32 110.3 2.9 3.8e-32 110.3 2.0 5.0 4 1 1 5 5 5 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 KFM04358.1 - 0.0058 15.7 1.3 0.62 9.1 0.1 3.1 2 1 1 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 KFM04358.1 - 0.0064 16.0 0.5 0.057 12.9 0.1 2.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase TPP_enzyme_M PF00205.17 KFM04358.1 - 0.017 14.8 0.1 12 5.6 0.0 3.2 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, central domain ComX PF05952.7 KFM04358.1 - 0.061 12.8 0.0 0.17 11.3 0.0 1.7 1 0 0 1 1 1 0 Bacillus competence pheromone ComX Pyr_redox PF00070.22 KFM04358.1 - 0.069 13.5 0.4 0.18 12.2 0.3 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KFM04358.1 - 0.08 11.9 0.1 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain FGF PF00167.13 KFM04359.1 - 1.8e-40 137.4 4.7 2.4e-40 137.1 3.2 1.1 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.8 KFM04359.1 - 5.7e-05 23.1 0.1 0.00012 22.1 0.1 1.5 1 1 0 1 1 1 1 Fascin domain TraW_N PF12477.3 KFM04359.1 - 0.074 13.0 0.2 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Sex factor F TraW protein N terminal SR-25 PF10500.4 KFM04359.1 - 2.5 7.5 8.2 0.24 10.8 2.7 1.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein zf-H2C2_2 PF13465.1 KFM04360.1 - 9.6e-58 189.7 46.5 7.5e-09 35.4 0.6 9.0 9 0 0 9 9 9 7 Zinc-finger double domain zf-C2H2 PF00096.21 KFM04360.1 - 4.3e-48 158.8 59.8 8.3e-08 32.1 0.5 8.1 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM04360.1 - 1.8e-29 99.8 50.9 1.8e-05 24.7 1.7 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM04360.1 - 2.5e-26 90.6 55.6 0.00061 19.5 0.3 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM04360.1 - 1.5e-12 47.2 24.6 0.035 14.2 0.2 7.8 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding C1_1 PF00130.17 KFM04360.1 - 2.8e-08 33.3 20.5 0.015 14.9 1.6 5.4 1 1 6 7 7 7 6 Phorbol esters/diacylglycerol binding domain (C1 domain) XPA_N PF01286.13 KFM04360.1 - 2.9e-08 33.2 22.7 0.16 11.7 0.2 7.9 8 0 0 8 8 8 2 XPA protein N-terminal Zn-ribbon_8 PF09723.5 KFM04360.1 - 3.9e-07 29.9 36.0 0.014 15.2 2.9 7.5 5 2 0 6 6 6 2 Zinc ribbon domain DNA_RNApol_7kD PF03604.8 KFM04360.1 - 4.4e-05 22.8 30.4 1.2 8.6 0.1 8.0 8 0 0 8 8 8 1 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.2 KFM04360.1 - 0.00014 21.6 30.9 4.9 7.0 5.1 5.3 1 1 1 3 3 3 0 Double zinc ribbon FYDLN_acid PF09538.5 KFM04360.1 - 0.00047 20.7 13.1 9.6 6.8 0.0 6.4 1 1 5 6 6 6 0 Protein of unknown function (FYDLN_acid) RRN7 PF11781.3 KFM04360.1 - 0.0012 18.2 26.0 0.18 11.3 0.1 7.5 8 0 0 8 8 8 1 RNA polymerase I-specific transcription initiation factor Rrn7 Elf1 PF05129.8 KFM04360.1 - 0.0041 16.7 15.0 1.1 8.9 0.2 4.3 1 1 3 4 4 4 2 Transcription elongation factor Elf1 like DrsE PF02635.10 KFM04360.1 - 0.0079 16.2 0.1 0.072 13.1 0.0 2.5 3 1 0 3 3 3 1 DsrE/DsrF-like family C1_4 PF07975.7 KFM04360.1 - 0.0079 16.1 26.2 1 9.4 0.8 6.1 1 1 6 7 7 7 1 TFIIH C1-like domain zf-Di19 PF05605.7 KFM04360.1 - 0.0097 16.0 5.4 0.03 14.4 1.2 5.6 1 1 6 7 7 7 3 Drought induced 19 protein (Di19), zinc-binding Zn_Tnp_IS1595 PF12760.2 KFM04360.1 - 0.035 13.9 40.6 5 7.0 3.3 6.0 3 2 2 5 5 5 0 Transposase zinc-ribbon domain C1_3 PF07649.7 KFM04360.1 - 0.038 14.0 25.9 6.1 6.9 0.1 7.2 8 0 0 8 8 8 0 C1-like domain TFIIS_C PF01096.13 KFM04360.1 - 0.041 13.5 30.7 5.9 6.6 0.1 7.7 6 2 0 6 6 6 0 Transcription factor S-II (TFIIS) LIM PF00412.17 KFM04360.1 - 0.047 13.7 27.7 1.6 8.8 0.2 5.9 2 2 4 6 6 6 0 LIM domain BolA PF01722.13 KFM04360.1 - 0.047 13.6 7.9 12 5.9 0.1 4.3 3 2 0 3 3 3 0 BolA-like protein zf-met PF12874.2 KFM04360.1 - 0.071 13.3 1.9 0.071 13.3 1.3 7.4 8 0 0 8 8 7 0 Zinc-finger of C2H2 type CpXC PF14353.1 KFM04360.1 - 0.11 12.4 24.5 12 5.8 1.1 7.0 2 2 4 6 6 6 0 CpXC protein YhfH PF14149.1 KFM04360.1 - 0.14 12.0 31.6 4.4 7.1 0.1 7.9 8 0 0 8 8 8 0 YhfH-like protein HTH_18 PF12833.2 KFM04360.1 - 0.14 12.2 0.5 1.4e+02 2.6 0.0 4.5 4 1 1 5 5 5 0 Helix-turn-helix domain zinc_ribbon_2 PF13240.1 KFM04360.1 - 0.33 10.5 45.1 1.8 8.1 1.2 7.4 5 3 1 6 6 6 0 zinc-ribbon domain zf-RING_3 PF14369.1 KFM04360.1 - 0.44 10.5 30.7 6.5 6.8 0.3 7.8 8 0 0 8 8 8 0 zinc-finger Zn_ribbon_recom PF13408.1 KFM04360.1 - 0.46 10.7 35.1 4.1 7.7 1.8 6.2 1 1 7 8 8 8 0 Recombinase zinc beta ribbon domain zf-UBP PF02148.14 KFM04360.1 - 0.47 10.6 37.5 3.1 7.9 1.2 6.4 1 1 4 5 5 5 0 Zn-finger in ubiquitin-hydrolases and other protein zf-ISL3 PF14690.1 KFM04360.1 - 0.58 10.2 36.8 6.1 6.9 0.4 8.0 8 0 0 8 8 8 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-H2C2_5 PF13909.1 KFM04360.1 - 0.8 10.0 0.1 0.8 10.0 0.1 8.8 8 3 0 8 8 8 0 C2H2-type zinc-finger domain HypA PF01155.14 KFM04360.1 - 1.8 8.2 22.9 35 4.1 3.4 4.6 1 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family Siva PF05458.7 KFM04360.1 - 3 7.3 12.1 2 7.9 1.2 3.0 1 1 2 3 3 3 0 Cd27 binding protein (Siva) Yippee-Mis18 PF03226.9 KFM04360.1 - 3.6 7.7 26.7 4.1 7.5 4.1 6.0 3 2 2 5 5 5 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-HIT PF04438.11 KFM04360.1 - 4.4 7.0 37.2 2.5 7.8 0.2 7.5 8 0 0 8 8 8 0 HIT zinc finger zf-AN1 PF01428.11 KFM04360.1 - 5.7 6.8 43.0 6.4 6.7 2.6 7.8 5 2 3 8 8 8 0 AN1-like Zinc finger Endonuclease_7 PF02945.10 KFM04360.1 - 5.8 6.6 25.8 0.097 12.3 2.4 4.2 1 1 4 5 5 4 0 Recombination endonuclease VII COX5B PF01215.14 KFM04360.1 - 6.1 6.5 21.5 1.5 8.5 0.5 5.3 1 1 6 7 7 7 0 Cytochrome c oxidase subunit Vb DUF2321 PF10083.4 KFM04360.1 - 7.8 5.9 19.9 3 7.3 0.3 5.3 1 1 4 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-LYAR PF08790.6 KFM04360.1 - 9.7 5.9 29.1 3.4 7.4 0.1 7.8 8 0 0 8 8 8 0 LYAR-type C2HC zinc finger LSR PF05624.9 KFM04362.1 - 7.4e-25 86.4 32.8 1.1e-24 85.8 22.8 1.3 1 0 0 1 1 1 1 Lipolysis stimulated receptor (LSR) V-set PF07686.12 KFM04362.1 - 4.4e-05 23.3 0.1 0.00097 19.0 0.1 2.8 1 1 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 KFM04363.1 - 6.4e-14 51.8 2.3 3e-06 27.2 0.4 2.3 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 KFM04363.1 - 1.4e-13 50.5 0.3 1.3e-07 31.3 0.1 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM04363.1 - 5.3e-13 48.8 3.5 3.7e-08 33.3 1.1 2.2 1 1 1 2 2 2 2 Immunoglobulin domain V-set PF07686.12 KFM04363.1 - 2.7e-11 43.3 2.1 1.2e-07 31.6 0.0 3.0 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_3 PF13927.1 KFM04363.1 - 2.2e-10 40.8 3.2 3e-06 27.6 1.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Herpes_gE PF02480.11 KFM04363.1 - 0.00011 20.5 4.9 0.62 8.2 0.0 3.0 1 1 3 4 4 4 4 Alphaherpesvirus glycoprotein E C2-set_2 PF08205.7 KFM04363.1 - 0.00033 20.5 0.4 0.001 18.9 0.2 1.8 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Shisa PF13908.1 KFM04363.1 - 0.026 14.6 2.5 0.05 13.7 1.7 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DSPc PF00782.15 KFM04364.1 - 8.2e-26 90.1 0.0 2e-25 88.8 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Gemini_AL3 PF01407.12 KFM04365.1 - 0.097 12.1 0.1 0.11 11.9 0.1 1.0 1 0 0 1 1 1 0 Geminivirus AL3 protein Pou PF00157.12 KFM04366.1 - 2.1e-39 133.0 0.1 5e-39 131.8 0.1 1.7 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.24 KFM04366.1 - 1.3e-17 63.1 2.7 3.3e-17 61.8 1.9 1.8 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFM04366.1 - 0.12 12.1 0.1 0.31 10.7 0.1 1.8 1 0 0 1 1 1 0 Homeobox KN domain TCR_zetazeta PF11628.3 KFM04367.1 - 1.1e-15 56.7 0.0 1.6e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 T-cell surface glycoprotein CD3 zeta chain ITAM PF02189.10 KFM04367.1 - 1.4e-07 31.2 1.6 0.007 16.5 0.0 2.9 3 0 0 3 3 3 2 Immunoreceptor tyrosine-based activation motif DUF217 PF02697.9 KFM04367.1 - 0.069 13.4 0.1 5.2 7.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized ACR, COG1753 CAP-ZIP_m PF15255.1 KFM04368.1 - 6e-23 81.3 1.0 6e-23 81.3 0.7 2.2 2 0 0 2 2 2 1 WASH complex subunit CAP-Z interacting, central region V-set PF07686.12 KFM04369.1 - 6.8e-19 67.8 0.0 1.2e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 KFM04369.1 - 7.2e-05 22.5 0.1 0.0003 20.5 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM04369.1 - 0.0012 18.9 0.0 0.0023 18.0 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Myelin-PO_C PF10570.4 KFM04369.1 - 0.0027 17.7 0.0 0.0051 16.8 0.0 1.4 1 0 0 1 1 1 1 Myelin-PO cytoplasmic C-term p65 binding region ig PF00047.20 KFM04369.1 - 0.0043 17.1 0.5 0.052 13.6 0.4 2.5 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFM04369.1 - 0.0071 16.8 1.5 0.11 13.0 0.1 2.7 2 1 0 2 2 2 1 Immunoglobulin domain Herpes_gE PF02480.11 KFM04369.1 - 0.016 13.4 0.0 0.82 7.8 0.0 2.1 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E MPC PF03650.8 KFM04370.1 - 1.6e-35 121.6 0.2 1.6e-35 121.5 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Neur_chan_LBD PF02931.18 KFM04371.1 - 1.5e-53 181.1 0.0 2.2e-53 180.5 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFM04371.1 - 3.2e-39 135.2 8.9 9.2e-34 117.3 2.7 2.2 1 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Cupin_4 PF08007.7 KFM04372.1 - 2.8e-92 309.3 0.0 3.7e-92 308.9 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.1 KFM04372.1 - 8.3e-07 28.7 0.2 5.9e-05 22.6 0.1 2.3 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.6 KFM04372.1 - 0.0003 20.2 0.1 0.0087 15.5 0.1 2.3 1 1 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 KFM04372.1 - 0.037 13.7 0.1 0.19 11.4 0.0 2.2 3 0 0 3 3 3 0 AraC-like ligand binding domain T2SF PF00482.18 KFM04372.1 - 0.046 13.6 0.1 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Arf PF00025.16 KFM04374.1 - 8.5e-55 184.6 0.0 9.9e-55 184.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KFM04374.1 - 2.1e-12 46.4 2.4 8.2e-08 31.3 0.3 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 KFM04374.1 - 6.6e-11 41.8 0.0 7.6e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KFM04374.1 - 1.5e-10 40.5 0.1 1.9e-10 40.2 0.1 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KFM04374.1 - 9.7e-09 35.1 0.0 1.4e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFM04374.1 - 3.7e-07 29.5 0.1 4.4e-07 29.2 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KFM04374.1 - 3.8e-05 24.1 0.0 6.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KFM04374.1 - 0.0021 17.5 0.0 0.014 14.8 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.1 KFM04374.1 - 0.0083 16.4 0.0 0.018 15.3 0.0 1.6 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KFM04374.1 - 0.0096 16.0 0.1 0.079 13.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 KFM04374.1 - 0.014 14.6 0.1 0.031 13.5 0.1 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B FtsK_SpoIIIE PF01580.13 KFM04374.1 - 0.042 13.3 0.2 0.86 9.0 0.0 2.1 1 1 0 2 2 2 0 FtsK/SpoIIIE family Pkinase_Tyr PF07714.12 KFM04375.1 - 1.5e-93 312.5 0.0 1.7e-93 312.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM04375.1 - 1.3e-43 149.0 0.0 1.6e-43 148.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KFM04375.1 - 0.02 13.9 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Nol1_Nop2_Fmu PF01189.12 KFM04377.1 - 6.5e-24 84.7 0.0 9.4e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 KFM04377.1 - 2e-05 24.6 0.0 3.1e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KFM04377.1 - 0.00035 20.6 0.0 0.0012 18.8 0.0 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 KFM04377.1 - 0.023 15.2 0.0 0.043 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Arf PF00025.16 KFM04378.1 - 6.5e-42 142.7 0.8 1.4e-41 141.6 0.0 1.9 2 1 0 2 2 2 1 ADP-ribosylation factor family Ras PF00071.17 KFM04378.1 - 2.5e-07 30.2 0.0 5.6e-07 29.0 0.0 1.7 1 1 0 1 1 1 1 Ras family SRPRB PF09439.5 KFM04378.1 - 6.7e-06 25.4 0.0 6.7e-06 25.4 0.0 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KFM04378.1 - 4.4e-05 22.3 0.0 4.4e-05 22.3 0.0 3.7 2 2 1 3 3 3 1 G-protein alpha subunit MMR_HSR1 PF01926.18 KFM04378.1 - 5.3e-05 23.1 0.3 0.00012 21.9 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KFM04378.1 - 0.0026 18.2 1.7 0.011 16.1 0.0 2.5 2 1 0 2 2 2 1 Miro-like protein DUF1395 PF07160.7 KFM04378.1 - 0.26 10.7 15.2 0.05 13.0 7.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1395) MIP-T3 PF10243.4 KFM04378.1 - 0.32 9.4 27.7 0.42 9.0 19.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SNARE PF05739.14 KFM04379.1 - 5.4e-14 51.6 3.4 5.4e-14 51.6 2.4 2.7 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 KFM04379.1 - 9.5e-09 35.3 7.9 9.5e-09 35.3 5.4 2.9 3 0 0 3 3 3 1 Syntaxin ALO PF04030.9 KFM04379.1 - 0.0015 18.1 0.7 0.0025 17.4 0.5 1.4 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase Fe_bilin_red PF05996.7 KFM04379.1 - 0.12 11.8 3.7 0.059 12.8 0.7 1.8 2 0 0 2 2 2 0 Ferredoxin-dependent bilin reductase GTPase_Cys_C PF12631.2 KFM04379.1 - 0.15 12.5 2.5 0.29 11.5 0.1 2.6 2 2 1 3 3 3 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Filo_VP35 PF02097.10 KFM04379.1 - 0.91 8.6 8.4 0.11 11.6 0.8 2.1 1 1 1 3 3 3 0 Filoviridae VP35 DASH_Dad3 PF08656.5 KFM04379.1 - 1.2 8.8 8.2 0.76 9.5 0.5 3.3 2 1 1 3 3 3 0 DASH complex subunit Dad3 Fib_alpha PF08702.5 KFM04379.1 - 1.8 8.6 21.7 0.26 11.4 3.4 3.7 1 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Pox_A_type_inc PF04508.7 KFM04379.1 - 2.1 8.3 4.7 16 5.6 0.1 3.2 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Syntaxin-6_N PF09177.6 KFM04379.1 - 6.4 7.2 16.0 0.22 11.9 2.1 3.4 2 2 1 3 3 3 0 Syntaxin 6, N-terminal Pkinase_Tyr PF07714.12 KFM04380.1 - 6.4e-97 323.6 0.0 7.5e-97 323.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM04380.1 - 1.9e-48 164.9 0.0 2.3e-48 164.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.1 KFM04380.1 - 1.1e-15 57.7 0.1 1.8e-15 57.0 0.1 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Kdo PF06293.9 KFM04380.1 - 0.0074 15.3 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4518 PF15008.1 KFM04381.1 - 7.6e-87 290.6 0.1 8.6e-87 290.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4518) QLQ PF08880.6 KFM04381.1 - 0.057 12.8 0.7 0.22 10.9 0.0 2.1 2 0 0 2 2 2 0 QLQ Ish1 PF10281.4 KFM04381.1 - 0.081 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein zf-C2H2 PF00096.21 KFM04382.1 - 2.5e-06 27.4 42.5 0.039 14.3 1.4 6.4 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-met PF12874.2 KFM04382.1 - 0.048 13.8 14.4 0.2 11.8 0.4 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFM04382.1 - 1.8 8.5 21.9 1.3 9.0 2.6 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger Yippee-Mis18 PF03226.9 KFM04382.1 - 7.3 6.7 13.3 3 7.9 2.4 3.3 3 0 0 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly AKAP95 PF04988.7 KFM04384.1 - 0.00029 20.6 1.9 0.00042 20.1 1.0 1.5 1 1 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_2 PF12756.2 KFM04384.1 - 0.0034 17.4 1.0 0.0034 17.4 0.7 1.5 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Mut7-C PF01927.11 KFM04384.1 - 0.022 14.7 1.9 0.59 10.0 0.1 2.3 1 1 1 2 2 2 0 Mut7-C RNAse domain zf-met PF12874.2 KFM04384.1 - 1.6 9.0 6.0 33 4.8 4.2 2.5 1 1 0 1 1 1 0 Zinc-finger of C2H2 type I-set PF07679.11 KFM04386.1 - 2.3e-13 49.8 0.2 2.2e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.12 KFM04386.1 - 6.2e-12 45.4 0.7 1.1e-11 44.6 0.1 1.7 2 0 0 2 2 2 1 Immunoglobulin V-set domain Ig_2 PF13895.1 KFM04386.1 - 3.5e-09 36.6 1.1 6.4e-07 29.4 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.7 KFM04386.1 - 1.2e-06 28.3 0.8 0.00017 21.4 0.1 2.3 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain ig PF00047.20 KFM04386.1 - 1.2e-05 25.3 9.6 4.9e-05 23.3 2.0 3.5 2 2 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.1 KFM04386.1 - 0.00041 20.7 7.3 0.074 13.5 0.4 2.8 2 2 0 2 2 2 2 Immunoglobulin domain Peptidase_M56 PF05569.6 KFM04386.1 - 0.0081 15.1 0.1 0.011 14.7 0.1 1.2 1 0 0 1 1 1 1 BlaR1 peptidase M56 C1-set PF07654.10 KFM04386.1 - 0.0095 15.9 0.7 0.51 10.3 0.1 2.3 2 0 0 2 2 2 1 Immunoglobulin C1-set domain TMEM154 PF15102.1 KFM04386.1 - 0.078 12.6 0.2 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family Rifin_STEVOR PF02009.11 KFM04386.1 - 0.082 12.5 0.3 0.58 9.7 0.1 2.0 2 0 0 2 2 2 0 Rifin/stevor family DUF3753 PF12575.3 KFM04386.1 - 1.3 8.8 4.4 0.4 10.4 1.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) V-set PF07686.12 KFM04387.1 - 1.5e-07 31.2 0.0 1.8e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 KFM04387.1 - 2.2e-05 24.2 0.0 2.5e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 KFM04387.1 - 5.3e-05 23.2 0.3 0.00026 21.0 0.2 1.9 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 KFM04387.1 - 0.01 15.9 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain SEA PF01390.15 KFM04388.1 - 0.00033 20.3 0.1 0.00034 20.2 0.1 1.1 1 0 0 1 1 1 1 SEA domain Trypsin PF00089.21 KFM04389.1 - 6e-70 235.2 0.3 6.8e-70 235.0 0.2 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 KFM04389.1 - 5e-05 22.7 1.3 8.3e-05 21.9 0.9 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) DUF316 PF03761.10 KFM04389.1 - 0.0075 15.6 0.0 0.21 10.8 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF316) Trypsin PF00089.21 KFM04390.1 - 9.3e-64 215.0 0.3 1.7e-63 214.1 0.2 1.4 1 0 0 1 1 1 1 Trypsin SEA PF01390.15 KFM04390.1 - 6.7e-26 90.0 0.6 1.1e-25 89.3 0.4 1.4 1 0 0 1 1 1 1 SEA domain Ldl_recept_a PF00057.13 KFM04390.1 - 3.3e-23 81.3 37.4 4.6e-09 36.0 5.1 3.6 2 1 1 3 3 3 3 Low-density lipoprotein receptor domain class A CUB PF00431.15 KFM04390.1 - 2.6e-13 50.0 5.3 2.3e-06 27.6 0.2 2.9 3 0 0 3 3 3 2 CUB domain Calponin PF00402.13 KFM04391.1 - 1.7e-13 49.6 3.6 1.7e-13 49.6 2.5 2.4 3 0 0 3 3 3 1 Calponin family repeat CH PF00307.26 KFM04391.1 - 1.7e-13 50.5 0.0 2.3e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Abhydrolase_6 PF12697.2 KFM04392.1 - 1.9e-17 63.9 0.0 2.8e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFM04392.1 - 1.3e-14 54.1 0.0 1.9e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFM04392.1 - 9e-13 48.3 0.1 4e-10 39.6 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFM04392.1 - 1.2e-08 34.4 0.0 1.6e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Vint PF14623.1 KFM04392.1 - 0.0078 15.7 0.1 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Hint-domain UPF0227 PF05728.7 KFM04392.1 - 0.008 15.9 0.0 0.039 13.6 0.0 2.1 1 1 0 2 2 2 1 Uncharacterised protein family (UPF0227) BAAT_C PF08840.6 KFM04392.1 - 0.01 15.5 0.0 0.015 15.0 0.0 1.1 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2920 PF11144.3 KFM04392.1 - 0.026 13.5 0.0 0.12 11.3 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2920) B5 PF03484.10 KFM04392.1 - 0.031 14.1 0.0 7.2 6.5 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetase B5 domain Esterase PF00756.15 KFM04392.1 - 0.042 13.2 0.1 0.1 12.0 0.1 1.5 1 1 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.11 KFM04392.1 - 0.058 12.8 0.0 2.5 7.5 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PH PF00169.24 KFM04393.1 - 4.2e-10 39.7 1.1 1.2e-09 38.2 0.1 2.4 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 KFM04393.1 - 0.0001 22.5 0.4 0.0001 22.5 0.3 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 KFM04393.1 - 0.0013 18.7 0.1 0.0034 17.4 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PI-PLC-X PF00388.14 KFM04394.1 - 1e-05 25.0 0.0 1.4e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain V-set PF07686.12 KFM04395.1 - 1.5e-07 31.3 0.1 6.5e-05 22.7 0.1 2.1 2 0 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.1 KFM04395.1 - 0.00027 20.9 0.5 0.075 13.1 0.0 2.4 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 KFM04395.1 - 0.03 14.4 0.4 2.3 8.4 0.0 3.0 2 1 0 2 2 2 0 Immunoglobulin domain I-set PF07679.11 KFM04395.1 - 0.057 13.2 0.0 0.33 10.8 0.0 2.1 3 0 0 3 3 3 0 Immunoglobulin I-set domain C2-set_2 PF08205.7 KFM04396.1 - 2.9e-17 62.3 0.1 9.7e-17 60.6 0.0 1.7 2 1 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.1 KFM04396.1 - 6.2e-09 35.8 0.1 4.9e-06 26.5 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 KFM04396.1 - 1.7e-08 34.8 0.5 4e-05 24.0 0.2 2.5 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 KFM04396.1 - 0.00012 22.1 0.5 0.0088 16.1 0.0 2.7 2 1 0 3 3 3 1 Immunoglobulin domain I-set PF07679.11 KFM04396.1 - 0.00041 20.1 0.1 0.034 14.0 0.0 2.7 2 1 0 2 2 2 1 Immunoglobulin I-set domain C1-set PF07654.10 KFM04396.1 - 0.031 14.2 0.1 2.4 8.2 0.0 2.4 2 1 0 2 2 2 0 Immunoglobulin C1-set domain RRM_6 PF14259.1 KFM04398.1 - 1.6e-08 34.4 0.0 4.7e-08 32.8 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFM04398.1 - 9e-07 28.4 0.0 2.6e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM04398.1 - 0.00079 19.2 0.0 0.0018 18.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CENP-P PF13096.1 KFM04399.1 - 6.5e-35 120.0 1.5 6.5e-35 120.0 1.0 1.9 2 1 0 2 2 2 1 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P TMEM219 PF14940.1 KFM04399.1 - 0.13 11.3 0.5 0.2 10.7 0.4 1.2 1 0 0 1 1 1 0 Transmembrane 219 Kinesin-relat_1 PF12711.2 KFM04399.1 - 0.18 12.2 4.3 0.13 12.6 1.5 1.9 2 1 0 2 2 2 0 Kinesin motor SlyX PF04102.7 KFM04399.1 - 0.42 11.0 2.2 2.9 8.3 0.1 2.6 3 0 0 3 3 3 0 SlyX LRR_8 PF13855.1 KFM04400.1 - 4.2e-21 74.4 3.8 9.4e-09 34.9 0.0 3.4 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KFM04400.1 - 4.6e-16 58.0 5.6 2.6e-05 23.7 0.0 4.5 2 2 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM04400.1 - 4.9e-14 50.2 2.4 0.033 14.1 0.0 6.5 6 0 0 6 6 6 4 Leucine Rich Repeat LRR_6 PF13516.1 KFM04400.1 - 3e-06 26.7 1.6 5.9 7.2 0.1 5.6 6 0 0 6 6 6 1 Leucine Rich repeat LRR_5 PF13306.1 KFM04400.1 - 3.6e-06 26.6 0.6 0.027 14.1 0.0 2.3 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_7 PF13504.1 KFM04400.1 - 1.5e-05 24.4 4.7 2.9 8.4 0.0 5.6 5 0 0 5 5 5 1 Leucine rich repeat LRR_8 PF13855.1 KFM04401.1 - 6.3e-68 224.4 45.7 3.5e-12 45.8 0.7 9.2 5 3 4 9 9 9 9 Leucine rich repeat LRR_4 PF12799.2 KFM04401.1 - 2.4e-45 151.5 61.8 8e-06 25.3 0.1 12.6 5 4 10 15 15 15 14 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM04401.1 - 8.9e-29 95.1 45.8 0.0041 16.9 0.1 19.3 18 3 3 21 21 21 7 Leucine Rich Repeat LRR_5 PF13306.1 KFM04401.1 - 1.5e-19 69.9 8.0 5.4e-06 26.1 0.0 5.5 2 2 1 4 4 4 4 Leucine rich repeats (6 copies) LRR_9 PF14580.1 KFM04401.1 - 6.3e-12 45.3 10.8 0.00017 21.2 0.1 4.9 3 2 1 4 4 4 4 Leucine-rich repeat LRRNT PF01462.13 KFM04401.1 - 7.6e-12 44.3 21.1 2.5e-07 30.0 1.5 6.3 6 0 0 6 6 6 2 Leucine rich repeat N-terminal domain LRR_6 PF13516.1 KFM04401.1 - 2.8e-11 42.2 50.5 6 7.2 0.0 16.9 17 2 0 17 17 17 3 Leucine Rich repeat LRR_7 PF13504.1 KFM04401.1 - 3.4e-11 41.4 39.9 0.041 14.0 0.0 16.5 19 1 1 20 20 20 2 Leucine rich repeat LRR_8 PF13855.1 KFM04402.1 - 2.1e-46 155.5 23.2 1.3e-15 56.9 0.1 6.6 5 2 1 6 6 6 5 Leucine rich repeat LRR_4 PF12799.2 KFM04402.1 - 2.1e-35 119.7 30.9 1.8e-06 27.4 0.3 9.3 3 1 7 10 10 10 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM04402.1 - 3.3e-27 90.3 26.0 0.16 12.0 0.0 13.8 13 1 1 14 14 13 8 Leucine Rich Repeat LRR_6 PF13516.1 KFM04402.1 - 2.7e-17 60.8 25.2 0.031 14.3 0.0 12.0 12 1 1 13 13 12 6 Leucine Rich repeat LRR_7 PF13504.1 KFM04402.1 - 2.5e-12 44.8 25.4 1.6 9.2 0.1 12.2 14 0 0 14 14 12 3 Leucine rich repeat VWC PF00093.13 KFM04402.1 - 2.8e-11 43.3 13.3 6.4e-11 42.1 9.2 1.6 1 0 0 1 1 1 1 von Willebrand factor type C domain LRR_5 PF13306.1 KFM04402.1 - 1.2e-09 37.9 0.9 0.0002 21.0 0.0 3.3 2 1 1 3 3 3 2 Leucine rich repeats (6 copies) LRR_9 PF14580.1 KFM04402.1 - 1.7e-05 24.4 4.6 0.028 13.9 0.2 4.9 1 1 3 5 5 5 2 Leucine-rich repeat FNIP PF05725.7 KFM04402.1 - 0.0045 16.9 9.1 5.6 7.0 0.3 4.8 4 0 0 4 4 4 1 FNIP Repeat Amnionless PF14828.1 KFM04402.1 - 0.17 10.3 10.5 0.27 9.6 7.3 1.2 1 0 0 1 1 1 0 Amnionless LRRNT PF01462.13 KFM04402.1 - 0.27 10.7 9.4 0.21 11.0 0.1 3.6 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain Ins_P5_2-kin PF06090.7 KFM04403.1 - 2.7e-92 309.1 1.0 3.1e-92 308.9 0.7 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase CUB PF00431.15 KFM04404.1 - 4.5e-20 71.7 0.0 6.9e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 CUB domain PDGF PF00341.12 KFM04404.1 - 1.2e-09 38.1 4.2 2.1e-09 37.3 2.9 1.4 1 0 0 1 1 1 1 PDGF/VEGF domain HTH_Tnp_Mu_2 PF09039.6 KFM04404.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Mu DNA binding, I gamma subdomain DUF1830 PF08865.6 KFM04405.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1830) Cullin_binding PF03556.10 KFM04406.1 - 2.8e-32 111.3 5.6 3.8e-32 110.8 3.9 1.2 1 0 0 1 1 1 1 Cullin binding Peptidase_M10 PF00413.19 KFM04407.1 - 8.3e-65 217.2 0.0 1.2e-64 216.6 0.0 1.3 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.14 KFM04407.1 - 2.1e-32 110.5 6.5 2.4e-13 49.5 0.0 4.4 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.13 KFM04407.1 - 2.7e-11 43.2 0.0 4.8e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.19 KFM04407.1 - 0.012 15.0 0.1 4.5 6.6 0.0 2.3 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.1 KFM04407.1 - 0.014 15.9 0.0 0.029 14.8 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KFM04407.1 - 0.056 13.3 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 KFM04407.1 - 0.15 12.0 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF3152 PF11350.3 KFM04407.1 - 0.17 11.3 0.0 1.8 8.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3152) Reprolysin_4 PF13583.1 KFM04407.1 - 0.22 11.0 0.0 0.38 10.2 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KFM04408.1 - 7.5e-61 204.3 0.0 1.4e-60 203.4 0.0 1.5 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.14 KFM04408.1 - 1e-41 140.4 10.1 7.3e-13 48.0 0.1 4.5 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.13 KFM04408.1 - 6.6e-12 45.2 0.0 1.3e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.19 KFM04408.1 - 0.0022 17.4 0.1 1.6 8.0 0.0 2.3 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.1 KFM04408.1 - 0.0086 16.5 0.2 0.018 15.5 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KFM04408.1 - 0.059 13.2 0.3 0.11 12.4 0.2 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M10 PF00413.19 KFM04409.1 - 1.1e-59 200.6 0.1 2.2e-59 199.5 0.0 1.6 2 0 0 2 2 2 1 Matrixin Hemopexin PF00045.14 KFM04409.1 - 1.1e-36 124.2 10.9 3.8e-13 48.9 0.8 4.3 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.13 KFM04409.1 - 1e-10 41.4 0.2 2.3e-10 40.2 0.2 1.7 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Reprolysin_3 PF13582.1 KFM04409.1 - 7.1e-06 26.5 0.1 0.00023 21.7 0.0 2.7 2 1 1 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.19 KFM04409.1 - 0.00018 20.9 0.4 0.58 9.5 0.0 2.4 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Reprolysin_5 PF13688.1 KFM04409.1 - 0.0011 18.9 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 KFM04409.1 - 0.0032 17.5 0.0 0.014 15.4 0.0 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like DUF3152 PF11350.3 KFM04409.1 - 0.0069 15.9 0.2 0.039 13.4 0.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3152) Reprolysin_4 PF13583.1 KFM04409.1 - 0.0091 15.5 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.6 KFM04409.1 - 0.01 15.6 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M54 DUF2498 PF10692.4 KFM04409.1 - 0.01 15.4 0.0 1 9.0 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2498) Peptidase_M66 PF10462.4 KFM04409.1 - 0.062 12.1 0.1 0.1 11.4 0.1 1.3 1 0 0 1 1 1 0 Peptidase M66 Reprolysin PF01421.14 KFM04409.1 - 0.19 11.2 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease Peptidase_M10 PF00413.19 KFM04410.1 - 1.4e-60 203.4 0.0 2.3e-60 202.8 0.0 1.3 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.14 KFM04410.1 - 9.8e-44 146.8 6.2 8.4e-14 51.0 0.0 4.3 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.13 KFM04410.1 - 1.5e-14 53.7 0.1 3e-14 52.7 0.1 1.6 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.19 KFM04410.1 - 0.0051 16.2 0.1 0.78 9.1 0.0 2.3 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.1 KFM04410.1 - 0.0066 16.9 0.2 0.014 15.9 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KFM04410.1 - 0.034 14.0 0.1 0.053 13.4 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 KFM04410.1 - 0.049 13.6 0.1 0.075 13.0 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M50B PF13398.1 KFM04410.1 - 0.1 11.9 0.1 1.4 8.2 0.2 2.0 2 0 0 2 2 2 0 Peptidase M50B-like Reprolysin_4 PF13583.1 KFM04410.1 - 0.11 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.6 KFM04410.1 - 0.13 12.0 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M54 Peptidase_M10 PF00413.19 KFM04411.1 - 9.3e-66 220.3 0.0 1.3e-65 219.8 0.0 1.2 1 0 0 1 1 1 1 Matrixin PG_binding_1 PF01471.13 KFM04411.1 - 3.3e-09 36.5 0.0 5.5e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.19 KFM04411.1 - 0.0018 17.6 0.1 0.19 11.0 0.1 2.2 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.1 KFM04411.1 - 0.0084 16.6 0.8 0.014 15.9 0.6 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFM04411.1 - 0.056 12.9 0.1 0.077 12.5 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KFM04411.1 - 0.066 13.1 0.3 0.097 12.5 0.2 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M43 PF05572.8 KFM04411.1 - 0.073 12.6 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Reprolysin_2 PF13574.1 KFM04411.1 - 0.12 12.4 0.1 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 KFM04411.1 - 0.15 11.3 0.0 0.68 9.2 0.0 1.8 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase Synaphin PF05835.7 KFM04412.1 - 1.6e-40 138.5 17.3 1.7e-40 138.3 12.0 1.0 1 0 0 1 1 1 1 Synaphin protein DUF4407 PF14362.1 KFM04412.1 - 1.3 7.9 8.4 1.6 7.6 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Borrelia_P83 PF05262.6 KFM04412.1 - 1.7 6.8 10.0 1.7 6.8 6.9 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein CAF-1_p150 PF11600.3 KFM04412.1 - 2.8 7.2 20.8 3.9 6.8 14.4 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Stm1_N PF09598.5 KFM04412.1 - 6.1 7.6 11.1 9.2e+02 0.6 7.7 2.2 1 1 0 1 1 1 0 Stm1 APG6 PF04111.7 KFM04412.1 - 8.2 5.3 9.8 9.8 5.1 6.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 zf-C3HC4 PF00097.20 KFM04413.1 - 3.3e-09 36.2 9.3 3.3e-09 36.2 6.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM04413.1 - 8.9e-09 35.2 8.6 8.9e-09 35.2 5.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM04413.1 - 2.6e-08 33.5 8.6 2.6e-08 33.5 6.0 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFM04413.1 - 4.3e-06 26.2 8.0 4.3e-06 26.2 5.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM04413.1 - 3e-05 23.6 9.3 3e-05 23.6 6.4 2.6 2 1 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 KFM04413.1 - 0.0014 18.6 6.2 0.0014 18.6 4.3 2.5 2 1 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 KFM04413.1 - 0.0015 18.3 8.7 0.0015 18.3 6.1 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KFM04413.1 - 0.0058 16.1 6.2 0.0058 16.1 4.3 2.4 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain CDC45 PF02724.9 KFM04413.1 - 0.0097 13.9 0.1 0.0098 13.9 0.0 1.1 1 0 0 1 1 1 1 CDC45-like protein zf-Nse PF11789.3 KFM04413.1 - 0.017 14.6 3.9 0.03 13.8 2.7 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 KFM04413.1 - 0.021 14.5 3.6 0.064 12.9 2.5 1.9 1 0 0 1 1 1 0 RING-type zinc-finger GAGA PF09237.6 KFM04413.1 - 0.026 14.1 0.1 0.082 12.5 0.0 1.8 1 0 0 1 1 1 0 GAGA factor DUF4512 PF14975.1 KFM04413.1 - 0.04 14.7 0.2 0.086 13.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) DUF3337 PF11816.3 KFM04413.1 - 0.15 11.4 5.1 0.25 10.6 2.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3337) zf-Apc11 PF12861.2 KFM04413.1 - 0.31 10.9 3.6 0.81 9.5 2.5 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1272 PF06906.6 KFM04413.1 - 0.46 10.3 9.1 0.37 10.6 4.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-RING_6 PF14835.1 KFM04413.1 - 0.86 9.4 7.4 0.34 10.7 3.0 1.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein MFS_1 PF07690.11 KFM04414.1 - 6.3e-23 81.0 22.7 7.6e-23 80.7 15.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Neur_chan_LBD PF02931.18 KFM04415.1 - 6.5e-68 228.1 1.6 9.6e-68 227.5 1.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFM04415.1 - 1.3e-56 192.1 1.0 1.8e-56 191.6 0.7 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region MscL PF01741.13 KFM04415.1 - 0.073 13.2 0.4 0.16 12.1 0.3 1.5 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL TraB PF01963.12 KFM04416.1 - 5.3e-10 39.1 0.0 5.7e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 TraB family Stap_Strp_tox_C PF02876.12 KFM04416.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Staphylococcal/Streptococcal toxin, beta-grasp domain TraB PF01963.12 KFM04417.1 - 1e-07 31.7 0.0 7e-07 28.9 0.0 1.9 1 1 0 1 1 1 1 TraB family Pkinase PF00069.20 KFM04419.1 - 7.3e-49 166.2 0.0 1.2e-48 165.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM04419.1 - 2.4e-28 98.9 0.0 3.6e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PTEN_C2 PF10409.4 KFM04419.1 - 2.7e-26 91.8 0.1 5.5e-26 90.8 0.1 1.5 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DnaJ PF00226.26 KFM04419.1 - 5.5e-07 29.2 0.0 1.3e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Kinase-like PF14531.1 KFM04419.1 - 6.5e-05 22.0 0.0 0.00014 20.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like DSPc PF00782.15 KFM04419.1 - 0.0046 16.5 0.4 0.019 14.5 0.2 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFM04419.1 - 0.011 15.0 0.3 0.011 15.0 0.2 1.8 2 0 0 2 2 2 0 Protein-tyrosine phosphatase Seadorna_VP7 PF07387.6 KFM04419.1 - 0.083 11.7 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 KFM04419.1 - 0.14 11.8 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1211 PF06736.6 KFM04420.1 - 2.2e-49 165.5 8.6 3e-32 110.6 0.0 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF1211) Chordopox_A13L PF05961.6 KFM04420.1 - 0.052 13.4 0.3 0.052 13.4 0.2 2.1 2 0 0 2 2 2 0 Chordopoxvirus A13L protein PDEase_I PF00233.14 KFM04421.1 - 3.9e-94 314.8 4.6 8.9e-94 313.6 3.2 1.6 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.21 KFM04421.1 - 8.1e-40 136.4 0.0 7.1e-19 68.4 0.0 2.3 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.1 KFM04421.1 - 7.6e-14 51.9 0.0 1.4e-06 28.4 0.0 2.7 2 1 0 2 2 2 2 GAF domain GAF_2 PF13185.1 KFM04421.1 - 2.2e-09 37.9 0.0 0.00021 21.7 0.0 2.3 2 0 0 2 2 2 2 GAF domain DUF4316 PF14195.1 KFM04421.1 - 0.032 14.3 0.8 0.088 12.8 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) Lipocalin PF00061.18 KFM04423.1 - 3.6e-18 65.9 0.0 4.6e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_2 PF08212.7 KFM04423.1 - 1.5e-09 37.7 0.0 2.2e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Lipocalin-like domain Triabin PF03973.8 KFM04423.1 - 1.2e-05 25.0 0.1 0.00083 19.0 0.0 2.1 2 0 0 2 2 2 2 Triabin Glyco_hydro_39 PF01229.12 KFM04424.1 - 4.3e-149 497.0 0.0 5.3e-149 496.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 Sulfate_transp PF00916.15 KFM04425.1 - 3.1e-72 242.9 12.9 3.1e-72 242.9 8.9 2.5 4 0 0 4 4 4 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KFM04425.1 - 5.9e-29 99.5 3.0 5.9e-29 99.5 2.1 3.4 4 1 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KFM04425.1 - 4.5e-26 90.5 0.0 8.7e-26 89.6 0.0 1.5 1 0 0 1 1 1 1 STAS domain Neur_chan_LBD PF02931.18 KFM04426.1 - 8.6e-75 250.5 3.2 1.1e-74 250.2 2.2 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFM04426.1 - 1.1e-56 192.3 9.1 1.5e-56 191.9 6.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF2417 PF10329.4 KFM04426.1 - 0.62 9.4 9.2 1.1 8.6 6.4 1.3 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Neur_chan_LBD PF02931.18 KFM04427.1 - 5.4e-73 244.7 0.1 8.5e-73 244.0 0.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFM04427.1 - 3e-59 200.8 12.8 9.5e-57 192.6 8.8 2.1 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region PepSY_TM_3 PF13706.1 KFM04427.1 - 5.6 6.4 11.4 0.15 11.5 1.7 2.5 2 0 0 2 2 2 0 PepSY-associated TM helix THAP PF05485.7 KFM04428.1 - 1.6e-16 60.2 1.0 4.6e-16 58.7 0.7 1.7 1 0 0 1 1 1 1 THAP domain Cep57_CLD PF14073.1 KFM04428.1 - 4.9e-05 23.2 3.1 7.2e-05 22.6 2.2 1.2 1 0 0 1 1 1 1 Centrosome localisation domain of Cep57 RTBV_P46 PF06216.6 KFM04428.1 - 0.0035 16.2 0.4 0.0045 15.8 0.3 1.1 1 0 0 1 1 1 1 Rice tungro bacilliform virus P46 protein DUF4391 PF14335.1 KFM04428.1 - 0.0036 16.7 2.4 0.0052 16.2 1.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4391) ADIP PF11559.3 KFM04428.1 - 0.0046 16.8 9.6 0.0069 16.3 6.7 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DivIC PF04977.10 KFM04428.1 - 0.0062 16.0 3.0 0.01 15.2 2.1 1.4 1 0 0 1 1 1 1 Septum formation initiator 7TMR-HDED PF07697.6 KFM04428.1 - 0.0064 16.2 1.5 0.0086 15.8 1.0 1.1 1 0 0 1 1 1 1 7TM-HD extracellular Mitofilin PF09731.4 KFM04428.1 - 0.0072 15.0 0.2 0.0095 14.6 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Macoilin PF09726.4 KFM04428.1 - 0.008 14.5 4.3 0.01 14.1 3.0 1.1 1 0 0 1 1 1 1 Transmembrane protein Tropomyosin_1 PF12718.2 KFM04428.1 - 0.014 15.2 4.8 0.022 14.6 3.3 1.3 1 0 0 1 1 1 0 Tropomyosin like Tropomyosin PF00261.15 KFM04428.1 - 0.015 14.3 6.8 0.021 13.9 4.7 1.1 1 0 0 1 1 1 0 Tropomyosin L31 PF09784.4 KFM04428.1 - 0.015 15.3 1.9 0.027 14.5 1.3 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 GrpE PF01025.14 KFM04428.1 - 0.02 14.4 3.6 0.029 13.9 2.5 1.2 1 0 0 1 1 1 0 GrpE FemAB PF02388.11 KFM04428.1 - 0.024 13.3 1.1 0.032 12.9 0.7 1.1 1 0 0 1 1 1 0 FemAB family AAA_27 PF13514.1 KFM04428.1 - 0.028 12.1 2.1 0.034 11.8 1.4 1.0 1 0 0 1 1 1 0 AAA domain DUF4140 PF13600.1 KFM04428.1 - 0.03 14.7 0.7 0.043 14.2 0.5 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF3373 PF11853.3 KFM04428.1 - 0.063 11.8 1.4 0.082 11.4 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF607 PF04678.8 KFM04428.1 - 0.067 13.1 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF607 YPEB PF14620.1 KFM04428.1 - 0.068 12.1 2.2 0.092 11.7 1.6 1.1 1 0 0 1 1 1 0 YpeB sporulation IncA PF04156.9 KFM04428.1 - 0.084 12.4 5.0 0.12 12.0 3.5 1.1 1 0 0 1 1 1 0 IncA protein DUF1977 PF09320.6 KFM04428.1 - 0.1 12.8 1.9 0.18 12.0 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1977) Vac_Fusion PF02346.11 KFM04428.1 - 0.16 11.3 3.7 0.3 10.5 2.5 1.4 1 0 0 1 1 1 0 Chordopoxvirus fusion protein FliD_C PF07195.7 KFM04428.1 - 0.21 10.8 1.7 0.29 10.3 1.2 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Atg14 PF10186.4 KFM04428.1 - 0.26 10.2 10.7 0.37 9.6 7.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 EAP30 PF04157.11 KFM04428.1 - 0.28 10.3 3.3 0.36 9.9 2.3 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family DUF2951 PF11166.3 KFM04428.1 - 0.3 10.9 6.3 0.5 10.2 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) APG6 PF04111.7 KFM04428.1 - 0.34 9.9 4.1 0.47 9.4 2.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 FlaC_arch PF05377.6 KFM04428.1 - 0.46 10.4 2.9 0.76 9.7 2.0 1.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) ABC_tran_2 PF12848.2 KFM04428.1 - 0.56 10.0 9.5 0.98 9.3 6.6 1.3 1 0 0 1 1 1 0 ABC transporter 4HBT_3 PF13622.1 KFM04428.1 - 1.6 8.4 9.7 2.2 7.9 6.7 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily XhlA PF10779.4 KFM04428.1 - 1.8 8.5 4.4 2.7 7.9 3.0 1.3 1 0 0 1 1 1 0 Haemolysin XhlA AKNA PF12443.3 KFM04428.1 - 2.1 8.4 7.8 5.5 7.0 5.4 1.7 1 1 0 1 1 1 0 AT-hook-containing transcription factor DUF605 PF04652.11 KFM04428.1 - 4.1 6.6 14.0 4.6 6.5 9.7 1.1 1 0 0 1 1 1 0 Vta1 like DUF3391 PF11871.3 KFM04428.1 - 4.9 7.3 8.8 13 6.0 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) PAT1 PF09770.4 KFM04428.1 - 7.1 4.7 9.0 8.6 4.4 6.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1232 PF06803.7 KFM04429.1 - 5.8e-10 38.4 8.6 5.8e-10 38.4 5.9 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1232) zf-C3HC4_3 PF13920.1 KFM04429.1 - 4.3e-09 35.8 2.5 6.3e-09 35.3 1.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM04429.1 - 1.4e-08 34.6 7.1 2.1e-08 34.0 4.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM04429.1 - 1.7e-08 33.9 4.1 2.9e-08 33.2 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM04429.1 - 3.4e-08 33.1 6.7 5.6e-08 32.4 4.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 KFM04429.1 - 4.2e-08 32.9 4.8 1e-07 31.7 3.4 1.6 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KFM04429.1 - 2.5e-06 27.0 4.4 5e-06 26.1 3.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KFM04429.1 - 2.5e-05 23.8 1.3 2.5e-05 23.8 0.9 2.1 1 1 1 2 2 2 1 RING-type zinc-finger Cys_rich_CPXG PF14255.1 KFM04429.1 - 0.025 14.3 0.7 8.4 6.3 0.0 2.4 2 0 0 2 2 2 0 Cysteine-rich CPXCG zf-Apc11 PF12861.2 KFM04429.1 - 0.036 13.8 2.0 0.066 13.0 1.4 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 KFM04429.1 - 0.13 12.4 2.0 0.24 11.5 1.4 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger TerY-C PF15616.1 KFM04429.1 - 0.17 11.8 3.3 0.34 10.8 2.3 1.4 1 1 0 1 1 1 0 TerY-C metal binding domain DRP PF06044.7 KFM04429.1 - 0.69 8.8 3.0 5.4 5.9 0.0 2.3 2 0 0 2 2 2 0 Dam-replacing family zf-MIZ PF02891.15 KFM04429.1 - 1.7 8.1 8.3 3.6 7.1 5.8 1.6 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger Baculo_IE-1 PF05290.6 KFM04429.1 - 2.4 7.9 4.8 4.9 6.8 3.3 1.5 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-met2 PF12907.2 KFM04429.1 - 9.2 6.3 7.3 9.4 6.3 0.6 2.9 3 0 0 3 3 3 0 Zinc-binding HOOK PF05622.7 KFM04430.1 - 0 1083.9 78.1 0 1083.7 54.1 1.0 1 0 0 1 1 1 1 HOOK protein HALZ PF02183.13 KFM04430.1 - 0.00029 20.4 3.2 0.00029 20.4 2.2 9.4 10 1 2 12 12 12 2 Homeobox associated leucine zipper BLOC1_2 PF10046.4 KFM04430.1 - 0.0096 16.0 8.4 0.0096 16.0 5.8 8.0 4 2 6 10 10 10 3 Biogenesis of lysosome-related organelles complex-1 subunit 2 Reo_sigmaC PF04582.7 KFM04430.1 - 0.039 13.1 23.6 0.057 12.6 1.1 4.0 3 1 2 5 5 5 0 Reovirus sigma C capsid protein Myosin_tail_1 PF01576.14 KFM04430.1 - 0.38 8.4 101.9 0.14 9.8 27.0 3.9 1 1 2 4 4 4 0 Myosin tail ERM PF00769.14 KFM04430.1 - 2.6 7.4 98.6 2.5 7.5 14.3 4.8 2 1 1 4 4 4 0 Ezrin/radixin/moesin family NPV_P10 PF05531.7 KFM04430.1 - 2.8 8.2 39.9 0.59 10.4 2.2 8.3 5 3 3 8 8 8 0 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.1 KFM04430.1 - 5.1 5.4 66.2 0.075 11.4 16.3 3.3 3 0 0 3 3 3 0 AAA domain IncA PF04156.9 KFM04430.1 - 6.2 6.3 108.0 0.74 9.3 12.3 6.2 2 1 1 5 5 5 0 IncA protein zf-Di19 PF05605.7 KFM04431.1 - 5.7e-23 80.7 1.8 5.7e-23 80.7 1.3 1.9 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding ZZ PF00569.12 KFM04431.1 - 1.4e-10 40.5 7.1 1.4e-10 40.5 4.9 2.4 3 0 0 3 3 3 1 Zinc finger, ZZ type Di19_C PF14571.1 KFM04431.1 - 0.0033 17.7 4.4 0.0033 17.7 3.1 2.5 1 1 1 2 2 2 1 Stress-induced protein Di19, C-terminal zf-C2H2 PF00096.21 KFM04431.1 - 0.012 15.8 0.3 0.012 15.8 0.2 3.3 3 1 0 3 3 3 0 Zinc finger, C2H2 type Dicty_REP PF05086.7 KFM04431.1 - 0.013 13.3 4.9 0.017 12.9 3.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-C2H2_4 PF13894.1 KFM04431.1 - 0.015 15.5 0.1 0.015 15.5 0.1 3.5 3 1 0 3 3 3 0 C2H2-type zinc finger zf-ribbon_3 PF13248.1 KFM04431.1 - 0.17 11.1 2.3 2.5 7.4 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_jaz PF12171.3 KFM04431.1 - 0.2 11.8 0.1 0.2 11.8 0.1 2.6 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-LITAF-like PF10601.4 KFM04431.1 - 3.2 7.6 11.6 0.35 10.7 0.3 3.4 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain zf-H2C2_2 PF13465.1 KFM04431.1 - 9.5 6.7 10.5 0.36 11.2 0.1 3.4 4 0 0 4 4 4 0 Zinc-finger double domain PPTA PF01239.17 KFM04432.1 - 2.2e-54 178.6 14.1 4e-12 44.9 0.2 6.1 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat DUF4219 PF13961.1 KFM04432.1 - 1.6 8.2 11.7 14 5.2 0.1 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4219) Glyco_transf_10 PF00852.14 KFM04433.1 - 2.4e-92 309.1 1.9 3.2e-92 308.7 1.3 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) Neuregulin PF02158.10 KFM04434.1 - 1.2e-236 785.0 28.4 1.7e-236 784.5 19.7 1.2 1 0 0 1 1 1 1 Neuregulin family I-set PF07679.11 KFM04434.1 - 1.5e-14 53.5 0.9 7.5e-14 51.3 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM04434.1 - 1.6e-10 40.9 0.4 7.5e-10 38.7 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.1 KFM04434.1 - 1.1e-06 29.0 2.7 0.00022 21.6 0.0 3.3 2 1 1 3 3 3 1 Immunoglobulin domain ig PF00047.20 KFM04434.1 - 1.4e-05 25.0 0.3 6.1e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain C1-set PF07654.10 KFM04434.1 - 2.4e-05 24.2 1.9 4.8e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin C1-set domain C2-set_2 PF08205.7 KFM04434.1 - 6.4e-05 22.7 2.0 0.00053 19.8 0.0 2.8 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain V-set PF07686.12 KFM04434.1 - 7.2e-05 22.6 0.1 7.2e-05 22.6 0.1 2.7 3 0 0 3 3 3 1 Immunoglobulin V-set domain hEGF PF12661.2 KFM04434.1 - 0.0089 16.0 1.6 0.017 15.1 1.1 1.5 1 0 0 1 1 1 1 Human growth factor-like EGF EGF_2 PF07974.8 KFM04434.1 - 0.22 11.7 3.6 0.56 10.4 2.5 1.7 1 1 0 1 1 1 0 EGF-like domain EGF PF00008.22 KFM04434.1 - 0.27 11.2 3.3 0.68 9.9 2.3 1.7 1 1 0 1 1 1 0 EGF-like domain DUF3650 PF12368.3 KFM04434.1 - 3.8 7.1 6.3 4.2 6.9 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3650) CLTH PF10607.4 KFM04435.1 - 0.018 14.7 1.5 0.031 13.9 0.9 1.6 1 1 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain DUF1539 PF07560.6 KFM04435.1 - 0.025 14.4 2.9 2.5 8.0 0.2 2.5 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1539) DUF3883 PF13020.1 KFM04435.1 - 0.048 13.4 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3883) Chorein_N PF12624.2 KFM04436.1 - 2.5e-12 46.3 0.1 2.9e-11 42.9 0.0 2.7 3 0 0 3 3 3 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Ank_2 PF12796.2 KFM04437.1 - 3.9e-45 152.0 10.1 2.8e-18 66.0 0.2 3.8 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KFM04437.1 - 2e-44 147.2 7.6 5.7e-07 29.0 0.0 6.7 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.1 KFM04437.1 - 6.2e-43 143.8 7.6 2.2e-09 37.2 0.1 6.6 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM04437.1 - 7.2e-37 121.7 4.4 9.3e-07 28.5 0.0 6.9 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 KFM04437.1 - 5.3e-36 122.3 5.4 2.2e-09 37.5 0.1 5.4 2 1 4 6 6 6 6 Ankyrin repeats (many copies) SAM_1 PF00536.25 KFM04437.1 - 4e-26 90.9 0.0 3.2e-15 56.0 0.0 2.9 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFM04437.1 - 7.4e-23 80.1 0.2 3.2e-15 55.7 0.0 2.7 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) PID PF00640.18 KFM04438.1 - 3.1e-31 108.2 0.5 4e-31 107.8 0.3 1.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.8 KFM04438.1 - 3.7e-06 26.8 0.1 5.5e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PID_2 PF14719.1 KFM04438.1 - 7.2e-05 22.4 0.0 0.0001 22.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Coq4 PF05019.8 KFM04438.1 - 0.066 12.1 0.0 6.1 5.6 0.0 2.2 2 0 0 2 2 2 0 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Kdo PF06293.9 KFM04438.1 - 0.078 12.0 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Rft-1 PF04506.8 KFM04439.1 - 4.7e-102 342.1 28.0 1.6e-101 340.4 19.4 1.6 1 1 0 1 1 1 1 Rft protein Phtf-FEM1B_bdg PF12129.3 KFM04439.1 - 0.8 9.0 7.6 0.21 10.9 2.8 1.9 2 0 0 2 2 2 0 Male germ-cell putative homeodomain transcription factor MBT PF02820.13 KFM04440.1 - 1.3e-86 284.5 0.8 3e-24 84.7 0.1 4.4 4 0 0 4 4 4 4 mbt repeat DUF3588 PF12140.3 KFM04440.1 - 1.9e-42 144.1 0.1 4.3e-42 142.9 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3588) SAM_1 PF00536.25 KFM04440.1 - 9.3e-10 38.5 0.0 1.7e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFM04440.1 - 8.7e-07 28.7 0.0 2.3e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 KFM04440.1 - 0.00055 19.6 0.0 0.0012 18.5 0.0 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Ste50p-SAM PF09235.5 KFM04440.1 - 0.0059 16.5 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 Ste50p, sterile alpha motif Anophelin PF10731.4 KFM04440.1 - 4.8 7.3 6.1 11 6.1 4.2 1.6 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito Nucleo_P87 PF07267.6 KFM04440.1 - 9.8 4.7 7.0 14 4.1 4.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF3661 PF12400.3 KFM04441.1 - 6.2e-38 129.8 8.2 9.5e-38 129.1 5.7 1.3 1 0 0 1 1 1 1 Vaculolar membrane protein TMEM154 PF15102.1 KFM04441.1 - 0.24 11.1 2.3 0.46 10.1 1.6 1.6 1 1 0 1 1 1 0 TMEM154 protein family Fer4_13 PF13370.1 KFM04442.1 - 0.1 13.0 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain VIT PF08487.5 KFM04443.1 - 9.3e-46 154.3 2.5 3.1e-45 152.6 1.8 1.9 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 KFM04443.1 - 7.7e-25 87.6 0.1 1.3e-24 86.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 KFM04443.1 - 3.4e-21 76.1 0.1 5.5e-21 75.4 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 KFM04443.1 - 2e-20 73.0 0.0 3.5e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 KFM04443.1 - 3.4e-06 27.0 0.0 6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_CoxE PF05762.9 KFM04443.1 - 6e-06 25.5 0.0 1.1e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein DUF2201 PF09967.4 KFM04443.1 - 0.00019 21.4 0.1 0.00047 20.1 0.1 1.7 1 0 0 1 1 1 1 VWA-like domain (DUF2201) Ribosomal_TL5_C PF14693.1 KFM04443.1 - 0.024 14.8 0.3 9.6 6.4 0.0 2.8 2 1 0 2 2 2 0 Ribosomal protein TL5, C-terminal domain SPC12 PF06645.8 KFM04444.1 - 9.8e-34 115.0 0.2 1.2e-33 114.7 0.1 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) MFS_1 PF07690.11 KFM04444.1 - 0.0013 17.4 0.0 0.0015 17.2 0.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MerC PF03203.9 KFM04444.1 - 0.025 14.9 0.1 0.029 14.7 0.1 1.1 1 0 0 1 1 1 0 MerC mercury resistance protein DUF443 PF04276.7 KFM04444.1 - 0.076 12.4 0.1 0.088 12.2 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF443) DUF4395 PF14340.1 KFM04444.1 - 0.088 12.8 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4395) DUF2484 PF10658.4 KFM04444.1 - 0.14 12.3 1.1 0.19 11.8 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2484) SdpI PF13630.1 KFM04444.1 - 0.22 11.2 1.7 0.27 10.9 1.2 1.1 1 0 0 1 1 1 0 SdpI/YhfL protein family Glyco_transf_8 PF01501.15 KFM04445.1 - 3.4e-49 167.4 0.1 3.9e-49 167.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_tranf_2_3 PF13641.1 KFM04445.1 - 0.021 14.6 1.1 3.2 7.5 0.0 2.8 2 1 1 3 3 3 0 Glycosyltransferase like family 2 Bromodomain PF00439.20 KFM04446.1 - 1.6e-114 374.0 27.4 2.5e-23 81.7 0.1 6.6 6 0 0 6 6 6 6 Bromodomain BAH PF01426.13 KFM04446.1 - 4.7e-51 171.5 3.8 6.6e-27 93.6 0.9 2.8 2 0 0 2 2 2 2 BAH domain HMG_box PF00505.14 KFM04446.1 - 2.2e-14 53.4 0.6 2.2e-14 53.4 0.4 2.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFM04446.1 - 1.2e-10 41.5 1.2 3.7e-10 40.0 0.9 1.9 1 0 0 1 1 1 1 HMG-box domain 5_nucleotid PF05761.9 KFM04447.1 - 1.7e-159 531.1 5.9 1.9e-159 530.9 4.1 1.0 1 0 0 1 1 1 1 5' nucleotidase family PX PF00787.19 KFM04449.1 - 1.5e-19 69.8 2.0 1.8e-19 69.5 1.4 1.0 1 0 0 1 1 1 1 PX domain tRNA_bind PF01588.15 KFM04449.1 - 0.12 12.2 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Putative tRNA binding domain V-ATPase_H_C PF11698.3 KFM04449.1 - 0.12 12.3 0.4 0.14 12.0 0.3 1.3 1 1 0 1 1 1 0 V-ATPase subunit H EF-hand_8 PF13833.1 KFM04450.1 - 5.4e-30 102.7 17.6 6.7e-15 54.4 0.2 3.4 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.27 KFM04450.1 - 5.7e-27 90.9 24.6 1e-08 33.8 0.7 4.8 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.1 KFM04450.1 - 1.6e-26 92.1 9.7 3.5e-16 59.1 4.6 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KFM04450.1 - 7.7e-22 75.1 14.8 1.8e-07 30.4 1.3 4.9 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KFM04450.1 - 3.6e-13 48.1 24.3 1.2e-06 27.5 0.2 4.9 5 1 1 6 6 6 3 EF hand EF-hand_9 PF14658.1 KFM04450.1 - 3.6e-12 46.0 0.6 5.6e-06 26.1 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KFM04450.1 - 8.8e-07 28.6 7.1 0.011 15.5 0.0 3.1 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KFM04450.1 - 8.4e-05 22.5 0.9 0.0025 17.8 0.2 2.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.8 KFM04450.1 - 0.0024 17.6 0.1 0.13 12.0 0.0 2.2 1 1 1 2 2 2 1 Tellurite resistance protein TerB UPF0154 PF03672.8 KFM04450.1 - 0.025 14.1 0.0 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) DUF1707 PF08044.6 KFM04450.1 - 0.03 14.0 0.4 1 9.1 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1707) EF-hand_10 PF14788.1 KFM04450.1 - 0.054 13.1 0.9 0.054 13.1 0.6 3.0 3 1 1 4 4 3 0 EF hand vATP-synt_AC39 PF01992.11 KFM04450.1 - 0.065 12.3 0.7 0.08 12.0 0.5 1.1 1 0 0 1 1 1 0 ATP synthase (C/AC39) subunit PTS_2-RNA PF01885.11 KFM04450.1 - 0.1 11.8 0.0 0.57 9.4 0.0 1.9 2 0 0 2 2 2 0 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF21 PF01595.15 KFM04450.1 - 0.12 11.6 0.1 1.9 7.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF21 EMG1 PF03587.9 KFM04450.1 - 0.14 11.4 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 EMG1/NEP1 methyltransferase EFhand_Ca_insen PF08726.5 KFM04450.1 - 0.16 11.9 0.9 0.46 10.4 0.3 2.0 2 0 0 2 2 2 0 Ca2+ insensitive EF hand RNA_pol_Rpb4 PF03874.11 KFM04450.1 - 0.17 11.9 2.7 11 6.0 0.3 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb4 DUF1456 PF07308.8 KFM04450.1 - 0.19 11.7 2.7 6.3 6.9 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF1456) DSPc PF00782.15 KFM04451.1 - 2.9e-43 146.6 0.0 3.8e-43 146.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFM04451.1 - 7.1e-05 22.2 0.0 9.9e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KFM04451.1 - 0.0016 18.4 0.0 0.0023 18.0 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate WD40 PF00400.27 KFM04452.1 - 2.1e-82 268.3 19.9 1.2e-12 47.1 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KFM04452.1 - 7.3e-10 38.8 0.1 6.3e-06 26.0 0.0 2.7 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.4 KFM04452.1 - 0.00079 18.6 0.5 0.37 10.1 0.0 3.1 3 0 0 3 3 3 2 Proteasome subunit A N-terminal signature Cytochrom_D1 PF02239.11 KFM04452.1 - 0.00081 17.7 0.1 2.4 6.3 0.0 2.9 1 1 2 3 3 3 3 Cytochrome D1 heme domain Syntaxin-6_N PF09177.6 KFM04452.1 - 0.068 13.5 0.6 0.13 12.6 0.4 1.4 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Aminotran_1_2 PF00155.16 KFM04453.1 - 2e-78 263.8 0.0 2.7e-78 263.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Preseq_ALAS PF09029.5 KFM04453.1 - 1.9e-09 37.4 1.2 5.1e-09 36.0 0.8 1.8 1 1 0 1 1 1 1 5-aminolevulinate synthase presequence Cys_Met_Meta_PP PF01053.15 KFM04453.1 - 1.7e-07 29.9 0.0 1.2e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KFM04453.1 - 1.4e-06 27.2 0.0 2.3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KFM04453.1 - 0.00078 18.6 0.0 0.0014 17.8 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KFM04453.1 - 0.004 16.2 1.2 0.022 13.8 0.7 1.9 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cofilin_ADF PF00241.15 KFM04454.1 - 7.5e-26 90.4 0.5 1e-12 48.0 0.0 2.3 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein WD40 PF00400.27 KFM04454.1 - 3.8e-21 74.1 0.9 7.5e-08 31.9 0.0 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.3 KFM04454.1 - 0.005 15.0 0.0 1.5 6.8 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 PP2C PF00481.16 KFM04455.1 - 9.2e-34 116.9 0.0 2.5e-15 56.5 0.0 3.1 2 1 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 KFM04455.1 - 1.2e-05 25.0 0.0 0.039 13.6 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 KFM04455.1 - 0.00023 20.6 0.0 0.087 12.2 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C DUF4147 PF13660.1 KFM04456.1 - 5.7e-76 254.7 0.5 7.7e-76 254.3 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) MOFRL PF05161.8 KFM04456.1 - 2.3e-34 117.7 0.3 4.5e-34 116.8 0.2 1.5 1 0 0 1 1 1 1 MOFRL family Phage_antiter_Q PF06323.6 KFM04457.1 - 0.062 12.6 0.0 0.07 12.5 0.0 1.0 1 0 0 1 1 1 0 Phage antitermination protein Q DUF4515 PF14988.1 KFM04458.1 - 2e-15 57.0 19.3 2e-15 57.0 13.4 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4515) DUF4618 PF15397.1 KFM04458.1 - 0.18 11.0 29.4 0.1 11.9 17.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Aida_N PF08910.5 KFM04458.1 - 0.37 11.0 10.1 0.047 13.9 2.3 2.4 1 1 1 2 2 2 0 Aida N-terminus GAGA_bind PF06217.7 KFM04458.1 - 1.2 9.0 16.0 1.7 8.5 11.1 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family MalF_P2 PF14785.1 KFM04458.1 - 2.3 8.0 9.9 7.4 6.4 2.8 2.2 1 1 1 2 2 2 0 Maltose transport system permease protein MalF P2 domain DUF3469 PF11952.3 KFM04458.1 - 2.7 7.7 8.2 6 6.6 0.5 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3469) Pkinase PF00069.20 KFM04459.1 - 4.4e-66 222.6 0.0 6.3e-66 222.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM04459.1 - 2.9e-30 105.2 0.0 4e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM04459.1 - 0.03 13.2 0.0 0.057 12.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like DUF1669 PF07894.7 KFM04460.1 - 1.5e-104 349.2 0.0 4.4e-104 347.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1669) PLDc_2 PF13091.1 KFM04460.1 - 0.0023 17.6 0.1 0.0087 15.8 0.0 2.0 2 0 0 2 2 2 1 PLD-like domain LRR_4 PF12799.2 KFM04461.1 - 5.7e-48 159.8 53.7 2.2e-10 39.9 1.3 9.2 5 2 5 10 10 10 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM04461.1 - 1.8e-35 120.4 42.3 1.3e-08 34.4 3.2 6.7 3 2 4 7 7 7 7 Leucine rich repeat LRR_1 PF00560.28 KFM04461.1 - 2.3e-24 81.6 50.4 0.021 14.7 0.2 14.4 15 0 0 15 15 15 12 Leucine Rich Repeat LRR_7 PF13504.1 KFM04461.1 - 2.4e-11 41.8 52.5 0.22 11.8 0.2 14.5 15 0 0 15 15 15 5 Leucine rich repeat LRR_9 PF14580.1 KFM04461.1 - 4.9e-06 26.2 11.4 0.0011 18.5 2.3 3.8 1 1 2 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.1 KFM04461.1 - 5.6 7.3 41.4 24 5.4 0.0 12.0 12 3 2 14 14 14 0 Leucine Rich repeat RRM_1 PF00076.17 KFM04462.1 - 3.7e-44 148.2 0.1 8.3e-19 66.9 0.0 3.6 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM04462.1 - 2.8e-31 107.3 0.0 5.1e-12 45.5 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM04462.1 - 1.6e-25 88.7 0.3 7.5e-10 38.5 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFM04462.1 - 0.0048 16.7 0.0 1.6 8.5 0.0 2.9 2 0 0 2 2 2 2 RNA binding motif OB_RNB PF08206.6 KFM04462.1 - 0.018 14.5 0.0 2.5 7.6 0.0 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain RseA_C PF03873.8 KFM04462.1 - 0.022 14.6 0.3 0.083 12.7 0.2 2.0 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain Pkinase PF00069.20 KFM04463.1 - 3.9e-23 81.9 0.1 7.6e-23 80.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM04463.1 - 6.3e-22 77.8 0.0 9.2e-22 77.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Plectin PF00681.15 KFM04464.1 - 3.1e-45 151.4 0.0 1.4e-16 59.7 0.0 5.1 4 1 1 5 5 5 4 Plectin repeat LLC1 PF14945.1 KFM04465.1 - 3.4e-30 104.8 0.7 3.8e-30 104.7 0.5 1.0 1 0 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein Ank_2 PF12796.2 KFM04466.1 - 4.6e-14 52.5 0.0 7.3e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFM04466.1 - 6.1e-14 52.0 0.3 5.3e-09 36.3 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KFM04466.1 - 1.7e-13 49.6 0.0 3.6e-06 26.5 0.2 2.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KFM04466.1 - 8.1e-12 44.9 0.3 1.8e-09 37.4 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM04466.1 - 6.7e-10 38.2 0.2 0.00018 21.4 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ubiquitin_2 PF14560.1 KFM04466.1 - 1.1e-05 25.5 0.0 1.9e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 KFM04466.1 - 0.00014 21.1 0.0 0.00023 20.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family HEAT PF02985.17 KFM04467.1 - 1.5e-23 80.6 17.9 0.012 15.6 0.0 10.5 11 0 0 11 11 11 7 HEAT repeat HEAT_2 PF13646.1 KFM04467.1 - 4.3e-13 49.3 0.3 0.00066 19.9 0.0 6.1 3 2 4 7 7 7 3 HEAT repeats AF1Q PF15017.1 KFM04467.1 - 7.4e-07 28.9 0.1 7.4e-07 28.9 0.1 2.5 3 0 0 3 3 3 1 Drug resistance and apoptosis regulator Vac14_Fab1_bd PF12755.2 KFM04467.1 - 0.0014 18.9 2.1 4.8 7.6 0.0 5.3 4 3 2 6 6 6 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KFM04467.1 - 0.028 14.9 0.8 27 5.4 0.1 4.5 5 0 0 5 5 5 0 HEAT-like repeat Ras PF00071.17 KFM04468.1 - 5e-56 188.5 0.0 5.7e-56 188.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM04468.1 - 2.1e-20 73.3 0.0 3.5e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM04468.1 - 1.6e-14 53.5 0.0 1.7e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFM04468.1 - 3.8e-06 26.2 0.0 4.6e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFM04468.1 - 1.7e-05 24.3 0.1 5.8e-05 22.5 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFM04468.1 - 4.8e-05 23.2 0.0 6.9e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KFM04468.1 - 0.00043 20.3 0.0 0.0058 16.6 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 KFM04468.1 - 0.024 13.8 0.0 0.083 12.0 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF258 CNTF PF01110.12 KFM04468.1 - 0.047 12.9 0.0 0.074 12.3 0.0 1.2 1 0 0 1 1 1 0 Ciliary neurotrophic factor AAA_24 PF13479.1 KFM04468.1 - 0.079 12.5 0.0 0.22 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 KFM04468.1 - 0.098 12.3 0.0 0.17 11.6 0.0 1.6 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) F_actin_cap_B PF01115.12 KFM04468.1 - 0.13 11.4 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 F-actin capping protein, beta subunit DIT1_PvcA PF05141.7 KFM04468.1 - 0.13 11.5 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein Motile_Sperm PF00635.21 KFM04469.1 - 1.7e-30 104.8 0.1 3.3e-30 103.9 0.1 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain DUF904 PF06005.7 KFM04469.1 - 0.0044 17.2 0.4 0.0068 16.6 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF904) DUF964 PF06133.6 KFM04469.1 - 0.031 14.2 0.5 0.052 13.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF964) DUF972 PF06156.8 KFM04469.1 - 0.054 13.8 0.3 0.083 13.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) IF2_N PF04760.10 KFM04469.1 - 0.061 12.9 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region NUDE_C PF04880.8 KFM04469.1 - 0.61 10.4 7.5 0.21 11.9 1.2 2.3 1 1 1 2 2 2 0 NUDE protein, C-terminal conserved region APCDDC PF14921.1 KFM04470.1 - 2.4e-120 400.3 0.1 5.4e-90 300.9 0.0 2.1 1 1 1 2 2 2 2 Adenomatosis polyposis coli down-regulated 1 SNARE PF05739.14 KFM04471.1 - 2e-20 72.2 6.7 2.2e-20 72.1 1.5 3.0 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 KFM04471.1 - 1.3e-14 54.1 0.9 1.3e-14 54.1 0.6 2.5 2 1 0 2 2 2 1 Syntaxin Syntaxin_2 PF14523.1 KFM04471.1 - 0.0041 17.1 14.4 0.012 15.5 4.6 2.7 2 2 0 2 2 2 1 Syntaxin-like protein MCPsignal PF00015.16 KFM04471.1 - 0.0057 16.2 5.5 0.03 13.8 0.1 2.3 2 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain ODV-E18 PF10717.4 KFM04471.1 - 0.0079 15.6 1.3 0.19 11.1 0.3 2.3 2 0 0 2 2 2 1 Occlusion-derived virus envelope protein ODV-E18 DUF4477 PF14780.1 KFM04471.1 - 0.0079 15.5 5.2 0.085 12.2 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4477) DUF4471 PF14740.1 KFM04471.1 - 0.0095 15.1 1.8 0.018 14.2 1.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) DUF2116 PF09889.4 KFM04471.1 - 0.02 14.6 1.2 0.049 13.4 0.8 1.6 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Med11 PF10280.4 KFM04471.1 - 0.029 14.3 4.6 0.034 14.1 0.7 2.4 2 0 0 2 2 2 0 Mediator complex protein DUF3753 PF12575.3 KFM04471.1 - 0.037 13.8 0.5 0.08 12.7 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) ETRAMP PF09716.5 KFM04471.1 - 0.076 12.9 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF912 PF06024.7 KFM04471.1 - 0.076 13.0 0.7 0.19 11.8 0.5 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) CCDC-167 PF15188.1 KFM04471.1 - 0.23 11.4 10.4 0.47 10.4 1.0 3.3 2 2 1 3 3 3 0 Coiled-coil domain-containing protein 167 Syntaxin-6_N PF09177.6 KFM04471.1 - 0.24 11.8 11.7 0.36 11.2 1.4 3.2 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Herpes_US9 PF06072.6 KFM04471.1 - 0.29 10.9 2.2 0.74 9.6 0.2 2.2 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Med9 PF07544.8 KFM04471.1 - 0.39 10.4 0.1 0.39 10.4 0.1 3.6 3 1 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 DASH_Dam1 PF08653.5 KFM04471.1 - 0.47 10.2 2.1 53 3.6 0.1 3.1 3 0 0 3 3 3 0 DASH complex subunit Dam1 Synaptobrevin PF00957.16 KFM04471.1 - 0.64 9.6 15.6 0.034 13.7 4.2 3.2 3 2 0 3 3 3 0 Synaptobrevin DUF4635 PF15466.1 KFM04471.1 - 8.2 5.7 10.4 4.4 6.6 0.2 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4635) PBP1_TM PF14812.1 KFM04471.1 - 8.4 6.7 8.0 0.78 10.0 0.1 2.6 3 0 0 3 3 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_M17 PF00883.16 KFM04472.1 - 1e-93 313.6 0.0 1.3e-93 313.3 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain G-alpha PF00503.15 KFM04473.1 - 4.6e-104 348.2 1.8 5.2e-104 348.0 1.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KFM04473.1 - 1.7e-14 53.4 1.5 1.2e-13 50.6 0.4 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 KFM04473.1 - 6e-05 23.5 0.3 0.041 14.3 0.1 2.6 2 1 0 2 2 2 2 Miro-like protein GTP_EFTU PF00009.22 KFM04473.1 - 0.025 14.0 1.1 0.62 9.4 0.0 2.4 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain TH1 PF04858.8 KFM04474.1 - 7.7e-291 965.4 0.3 8.6e-291 965.2 0.2 1.0 1 0 0 1 1 1 1 TH1 protein Peptidase_C1 PF00112.18 KFM04475.1 - 6.4e-51 173.3 11.8 8.1e-51 173.0 8.2 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 KFM04475.1 - 0.048 12.1 0.8 0.08 11.4 0.3 1.5 2 0 0 2 2 2 0 Peptidase C1-like family Tubulin PF00091.20 KFM04476.1 - 3.1e-72 242.8 0.0 4.5e-72 242.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFM04476.1 - 1.5e-47 160.7 0.0 2.5e-47 160.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KFM04476.1 - 1.1e-05 25.5 0.0 2.2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KFM04476.1 - 0.0049 16.3 0.0 0.0094 15.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain ATP-synt_Eps PF04627.8 KFM04477.1 - 2.3e-19 68.6 2.9 2.5e-19 68.5 2.0 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain PRELI PF04707.9 KFM04478.1 - 1.7e-56 190.1 0.1 2e-56 189.9 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family zf-C2H2 PF00096.21 KFM04479.1 - 0.015 15.5 1.1 0.027 14.8 0.7 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KFM04479.1 - 0.034 14.3 0.4 0.05 13.7 0.3 1.3 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Endothelin PF00322.12 KFM04482.1 - 4.6e-05 22.5 3.9 4.6e-05 22.5 2.7 1.8 2 1 0 2 2 2 1 Endothelin family zf-C2H2 PF00096.21 KFM04483.1 - 2.4e-19 68.4 118.9 0.0061 16.8 0.3 15.5 15 0 0 15 15 15 10 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM04483.1 - 5.1e-07 29.6 90.5 0.0034 17.5 1.5 14.8 15 2 1 16 16 16 7 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFM04483.1 - 1.4e-06 28.3 2.4 0.00039 20.4 0.1 11.0 13 0 0 13 13 13 3 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KFM04483.1 - 1.6e-06 28.0 115.7 0.004 17.3 0.3 15.3 15 0 0 15 15 15 10 C2H2-type zinc finger zf-met PF12874.2 KFM04483.1 - 0.0018 18.4 3.4 0.024 14.8 0.2 11.9 13 0 0 13 13 13 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFM04483.1 - 0.044 13.6 0.1 0.044 13.6 0.1 12.7 14 0 0 14 14 14 0 C2H2-type zinc finger Peptidase_C14 PF00656.17 KFM04484.1 - 1.7e-20 73.7 0.0 6.3e-19 68.6 0.0 2.0 1 1 0 1 1 1 1 Caspase domain Alpha_kinase PF02816.13 KFM04485.1 - 3.6e-42 144.1 0.0 4.8e-42 143.7 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family Tsg PF04668.7 KFM04485.1 - 0.008 16.3 0.4 0.011 15.9 0.3 1.3 1 0 0 1 1 1 1 Twisted gastrulation (Tsg) protein conserved region zf-CCHC_3 PF13917.1 KFM04485.1 - 0.16 11.7 0.2 0.16 11.7 0.1 2.0 3 0 0 3 3 3 0 Zinc knuckle HECT PF00632.20 KFM04486.1 - 1.8e-93 313.1 0.1 2.5e-93 312.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 KFM04486.1 - 8.4e-48 159.8 27.3 4e-12 45.7 0.1 5.0 5 0 0 5 5 5 4 WW domain C2 PF00168.25 KFM04486.1 - 9.6e-18 63.8 0.1 2.2e-17 62.6 0.1 1.7 1 0 0 1 1 1 1 C2 domain E1-E2_ATPase PF00122.15 KFM04488.1 - 4.6e-18 65.1 0.0 1.2e-17 63.7 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 KFM04488.1 - 2.7e-15 57.0 0.0 6.6e-15 55.7 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFM04488.1 - 1.3e-13 51.8 0.2 4e-07 30.6 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFM04488.1 - 9.1e-13 47.9 0.0 2.9e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFM04488.1 - 0.00044 19.9 3.2 0.0013 18.4 0.8 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase ATP-synt_8 PF00895.15 KFM04488.1 - 0.43 10.8 8.9 4.5 7.5 0.5 3.9 3 0 0 3 3 3 0 ATP synthase protein 8 tRNA-synt_2 PF00152.15 KFM04489.1 - 2.2e-79 266.6 0.1 4.4e-79 265.6 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KFM04489.1 - 1.5e-10 40.7 0.0 2.9e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF1565 PF07602.6 KFM04489.1 - 0.012 14.7 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1565) Ferrochelatase PF00762.14 KFM04490.1 - 7.8e-106 353.6 0.0 9e-106 353.3 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Homeobox PF00046.24 KFM04492.1 - 1.8e-11 43.4 1.2 2.8e-11 42.8 0.8 1.2 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFM04492.1 - 4.5e-05 23.0 0.2 9.7e-05 21.9 0.0 1.6 2 0 0 2 2 2 1 Homeobox KN domain DUF2194 PF09960.4 KFM04492.1 - 0.054 11.5 0.2 0.052 11.5 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2194) PH_3 PF14593.1 KFM04492.1 - 0.071 13.0 0.6 0.087 12.7 0.4 1.1 1 0 0 1 1 1 0 PH domain LTXXQ PF07813.7 KFM04492.1 - 0.092 13.2 0.2 0.11 12.9 0.1 1.2 1 0 0 1 1 1 0 LTXXQ motif family protein WD40 PF00400.27 KFM04493.1 - 2.8e-27 93.5 18.9 1.4e-05 24.7 0.1 7.9 7 0 0 7 7 7 6 WD domain, G-beta repeat PITH PF06201.8 KFM04494.1 - 4.7e-46 156.3 0.0 7e-46 155.7 0.0 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 KFM04494.1 - 6.1e-15 54.7 0.0 1e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Sad1_UNC PF07738.8 KFM04494.1 - 0.0098 15.6 0.0 0.019 14.7 0.0 1.5 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal HLH PF00010.21 KFM04495.1 - 9.9e-12 44.3 2.1 2e-11 43.4 0.7 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Ras PF00071.17 KFM04496.1 - 4.6e-55 185.4 0.0 5.9e-55 185.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM04496.1 - 4.6e-16 59.3 0.0 6.8e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM04496.1 - 3.2e-13 49.3 0.0 5e-13 48.6 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFM04496.1 - 0.00016 21.2 0.0 0.00029 20.3 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFM04496.1 - 0.0047 16.1 0.1 0.017 14.2 0.1 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 KFM04496.1 - 0.0081 16.3 0.0 0.025 14.6 0.0 1.8 1 1 1 2 2 2 1 AAA domain ATP_bind_1 PF03029.12 KFM04496.1 - 0.012 15.1 0.5 0.28 10.6 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 KFM04496.1 - 0.13 11.8 0.2 0.38 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KFM04496.1 - 0.17 11.3 0.3 1.4 8.3 0.2 2.1 1 1 0 1 1 1 0 AAA domain IMS PF00817.15 KFM04497.1 - 2.1e-46 157.4 0.0 6e-46 155.9 0.0 1.7 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 KFM04497.1 - 4e-08 33.2 0.0 1.1e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KFM04497.1 - 2.2e-05 24.1 0.0 6.3e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif Cdd1 PF11731.3 KFM04497.1 - 0.0066 16.3 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 Pathogenicity locus DNA_pol_lambd_f PF10391.4 KFM04497.1 - 0.013 15.0 0.0 0.099 12.2 0.0 2.5 3 0 0 3 3 3 0 Fingers domain of DNA polymerase lambda HHH_5 PF14520.1 KFM04497.1 - 0.017 15.2 0.0 0.045 13.9 0.0 1.9 1 1 0 1 1 1 0 Helix-hairpin-helix domain REC114-like PF15165.1 KFM04497.1 - 0.1 12.3 1.0 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 Meiotic recombination protein REC114-like MBD_C PF14048.1 KFM04498.1 - 1.8e-25 89.3 0.6 4.8e-25 87.9 0.0 1.9 2 1 0 2 2 2 1 C-terminal domain of methyl-CpG binding protein 2 and 3 MBD PF01429.14 KFM04498.1 - 9e-12 44.3 0.5 1e-06 28.1 0.0 2.2 2 0 0 2 2 2 2 Methyl-CpG binding domain Pardaxin PF07425.6 KFM04498.1 - 0.096 12.0 0.9 0.22 10.9 0.6 1.6 1 0 0 1 1 1 0 Pardaxin RVT_1 PF00078.22 KFM04499.1 - 0.013 14.8 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) fn3 PF00041.16 KFM04500.1 - 7.5e-79 259.9 20.5 2.8e-15 56.2 0.1 6.4 6 0 0 6 6 6 6 Fibronectin type III domain I-set PF07679.11 KFM04500.1 - 6.3e-59 195.8 0.0 1.3e-16 60.2 0.0 5.7 5 0 0 5 5 5 4 Immunoglobulin I-set domain Neogenin_C PF06583.7 KFM04500.1 - 7e-56 190.1 5.4 1.4e-55 189.1 3.7 1.5 1 0 0 1 1 1 1 Neogenin C-terminus Ig_2 PF13895.1 KFM04500.1 - 1.2e-43 147.0 0.0 1.9e-12 47.1 0.0 5.7 5 0 0 5 5 5 4 Immunoglobulin domain V-set PF07686.12 KFM04500.1 - 3.5e-27 94.5 0.4 3.6e-09 36.5 0.0 7.7 6 3 0 6 6 6 4 Immunoglobulin V-set domain ig PF00047.20 KFM04500.1 - 2.8e-26 91.3 3.3 5.8e-09 35.9 0.1 6.0 6 1 0 6 6 5 3 Immunoglobulin domain Ig_3 PF13927.1 KFM04500.1 - 1.8e-24 85.9 6.4 3.6e-09 36.9 0.1 8.1 7 1 0 7 7 6 4 Immunoglobulin domain C2-set_2 PF08205.7 KFM04500.1 - 2e-10 40.4 3.6 0.031 14.1 0.0 5.1 6 0 0 6 6 5 3 CD80-like C2-set immunoglobulin domain Interfer-bind PF09294.5 KFM04500.1 - 2.4e-10 40.4 0.1 0.11 12.4 0.0 5.0 5 0 0 5 5 4 3 Interferon-alpha/beta receptor, fibronectin type III Herpes_gE PF02480.11 KFM04500.1 - 3.8e-06 25.4 0.3 0.028 12.7 0.2 4.0 4 0 0 4 4 4 1 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 KFM04500.1 - 5.9e-05 23.3 0.5 0.00015 22.1 0.3 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.6 KFM04500.1 - 0.0012 18.4 0.1 0.0025 17.5 0.1 1.4 1 0 0 1 1 1 1 Protocadherin Sp38 PF07354.7 KFM04500.1 - 0.0031 16.2 0.0 0.012 14.2 0.0 1.9 2 0 0 2 2 2 1 Zona-pellucida-binding protein (Sp38) V-set_CD47 PF08204.6 KFM04500.1 - 0.01 15.5 0.0 0.28 10.9 0.0 2.6 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain TMEM154 PF15102.1 KFM04500.1 - 0.1 12.3 1.6 0.23 11.1 0.5 2.1 1 1 1 2 2 2 0 TMEM154 protein family FAM176 PF14851.1 KFM04500.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 FAM176 family Arylsulfotrans PF05935.6 KFM04500.1 - 0.11 10.9 1.2 0.14 10.6 0.2 1.6 2 0 0 2 2 2 0 Arylsulfotransferase (ASST) DUF2369 PF10179.4 KFM04500.1 - 0.11 11.5 0.4 28 3.6 0.0 3.4 4 0 0 4 4 4 0 Uncharacterised conserved protein (DUF2369) DUF1049 PF06305.6 KFM04500.1 - 0.19 11.2 0.4 0.45 10.0 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Shisa PF13908.1 KFM04500.1 - 0.2 11.7 6.1 0.76 9.9 4.2 2.0 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator CD34_antigen PF06365.7 KFM04500.1 - 0.24 11.0 0.2 0.42 10.2 0.1 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family ANF_receptor PF01094.23 KFM04502.1 - 7e-91 304.5 0.2 8.8e-91 304.2 0.1 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.17 KFM04502.1 - 7.9e-74 247.9 16.6 1.3e-73 247.2 11.5 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.9 KFM04502.1 - 5.8e-15 54.7 8.8 5.8e-15 54.7 6.1 2.3 2 0 0 2 2 2 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.1 KFM04502.1 - 7.9e-11 41.8 0.3 6.8e-09 35.5 0.4 2.1 2 0 0 2 2 2 2 Periplasmic binding protein FDC-SP PF15215.1 KFM04502.1 - 0.06 13.6 1.1 0.17 12.2 0.8 1.7 1 0 0 1 1 1 0 Follicular dendritic cell secreted peptide WD40 PF00400.27 KFM04503.1 - 1.4e-39 132.5 12.9 5.7e-08 32.3 0.4 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat HEAT PF02985.17 KFM04504.1 - 0.58 10.3 0.0 0.58 10.3 0.0 3.3 4 1 0 4 4 4 0 HEAT repeat Glyco_hydro_56 PF01630.13 KFM04505.1 - 5.8e-119 396.6 0.0 6.9e-119 396.4 0.0 1.0 1 0 0 1 1 1 1 Hyaluronidase IFRD PF05004.8 KFM04506.1 - 9.4e-83 277.8 0.7 1.2e-82 277.5 0.5 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) IFRD_C PF04836.7 KFM04506.1 - 1e-25 89.6 0.5 1e-25 89.6 0.4 2.2 2 1 0 2 2 2 1 Interferon-related protein conserved region HEAT_2 PF13646.1 KFM04506.1 - 0.15 12.3 1.2 0.36 11.1 0.2 2.2 2 1 0 2 2 2 0 HEAT repeats OAS1_C PF10421.4 KFM04507.1 - 6e-63 211.7 0.0 1.1e-62 210.9 0.0 1.4 1 0 0 1 1 1 1 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus ubiquitin PF00240.18 KFM04507.1 - 2.6e-28 97.1 0.2 1e-18 66.5 0.0 3.1 2 1 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 KFM04507.1 - 5.7e-13 48.3 0.0 5e-08 32.5 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KFM04507.1 - 1.2e-07 31.8 0.0 0.014 15.6 0.0 2.7 2 0 0 2 2 2 2 Ubiquitin-like domain NTP_transf_2 PF01909.18 KFM04507.1 - 0.00044 20.5 0.0 0.00096 19.4 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain UN_NPL4 PF11543.3 KFM04507.1 - 0.019 15.2 0.0 0.27 11.5 0.0 2.4 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 Rad60-SLD_2 PF13881.1 KFM04507.1 - 0.042 13.7 0.5 0.7 9.7 0.1 2.6 1 1 1 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Sema PF01403.14 KFM04508.1 - 1e-167 558.0 0.0 1.2e-167 557.8 0.0 1.0 1 0 0 1 1 1 1 Sema domain PSI PF01437.20 KFM04508.1 - 0.0013 18.8 6.7 0.0013 18.8 4.6 1.9 2 0 0 2 2 2 1 Plexin repeat Aa_trans PF01490.13 KFM04509.1 - 1.1e-07 30.7 1.9 1.3e-07 30.5 1.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein G-alpha PF00503.15 KFM04510.1 - 4.2e-127 424.0 4.0 4.7e-127 423.8 2.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KFM04510.1 - 8.2e-14 51.2 0.1 7.6e-13 48.0 0.0 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 KFM04510.1 - 0.12 12.8 0.8 5.3 7.5 0.0 2.8 3 0 0 3 3 3 0 Miro-like protein G-alpha PF00503.15 KFM04511.1 - 1.2e-127 425.8 1.0 1.5e-127 425.5 0.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KFM04511.1 - 2e-14 53.2 2.6 8.7e-11 41.3 0.2 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFM04511.1 - 0.00072 18.7 0.6 0.98 8.5 0.1 2.5 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 KFM04511.1 - 0.01 16.3 0.2 0.7 10.3 0.0 3.0 2 1 1 3 3 3 0 Miro-like protein DUF2951 PF11166.3 KFM04511.1 - 0.015 15.1 0.3 0.049 13.4 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) AAA_29 PF13555.1 KFM04511.1 - 0.04 13.4 0.0 0.084 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sema PF01403.14 KFM04512.1 - 4.6e-176 585.6 0.0 5.3e-176 585.3 0.0 1.0 1 0 0 1 1 1 1 Sema domain PSI PF01437.20 KFM04512.1 - 0.00021 21.3 8.5 0.00054 20.0 5.9 1.8 1 0 0 1 1 1 1 Plexin repeat RRM_6 PF14259.1 KFM04513.1 - 1.4e-29 101.8 0.0 1.6e-13 50.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.18 KFM04513.1 - 2.6e-18 65.5 2.7 2.6e-18 65.5 1.9 2.0 2 0 0 2 2 2 1 G-patch domain RRM_1 PF00076.17 KFM04513.1 - 1.2e-15 56.8 0.0 2.7e-08 33.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.13 KFM04513.1 - 5.7e-11 41.3 3.5 1e-10 40.4 2.4 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_5 PF13893.1 KFM04513.1 - 5.2e-09 35.8 0.1 0.0014 18.4 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.2 KFM04513.1 - 7.2e-08 32.1 1.2 7.2e-08 32.1 0.9 2.5 3 0 0 3 3 3 1 DExH-box splicing factor binding site GSIII_N PF12437.3 KFM04513.1 - 0.0023 17.3 1.0 0.0056 16.1 0.7 1.6 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal zf-C2H2_4 PF13894.1 KFM04513.1 - 0.053 13.8 0.2 0.053 13.8 0.1 2.6 2 1 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KFM04513.1 - 0.14 12.5 0.2 0.14 12.5 0.1 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type 7tm_1 PF00001.16 KFM04514.1 - 3.5e-41 141.0 23.2 4.9e-41 140.5 16.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) KH_1 PF00013.24 KFM04515.1 - 2.1e-48 161.7 11.6 1.9e-17 62.6 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KFM04515.1 - 1.5e-34 117.0 19.8 1.7e-11 43.4 2.8 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KFM04515.1 - 5.6e-14 51.4 4.5 0.00036 20.0 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KFM04515.1 - 3.5e-07 29.7 1.2 0.016 14.8 0.1 3.3 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 KFM04515.1 - 0.0028 17.4 4.8 6.7 6.6 0.1 3.4 3 0 0 3 3 3 3 NusA-like KH domain Abhydrolase_6 PF12697.2 KFM04516.1 - 9.4e-18 64.9 1.9 2.9e-08 33.8 0.3 2.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFM04516.1 - 1.1e-11 44.6 0.1 1.3e-11 44.4 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFM04516.1 - 1.5e-07 31.2 0.1 0.00021 20.9 0.0 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.13 KFM04516.1 - 0.0031 16.8 0.1 0.012 14.9 0.0 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family Hydrolase_4 PF12146.3 KFM04516.1 - 0.074 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_6 PF12697.2 KFM04517.1 - 8.8e-18 65.0 3.1 1.2e-09 38.3 0.1 2.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFM04517.1 - 8.2e-11 41.8 0.0 9.2e-11 41.6 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFM04517.1 - 4.9e-09 36.0 0.0 8.1e-06 25.5 0.0 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.13 KFM04517.1 - 0.00035 19.9 0.0 0.00047 19.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_4 PF08386.5 KFM04517.1 - 0.1 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 TAP-like protein Peptidase_S9 PF00326.16 KFM04517.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Peptidase_M20 PF01546.23 KFM04518.1 - 4.3e-37 127.4 0.0 5.5e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KFM04518.1 - 4.3e-14 52.1 0.0 7.2e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KFM04518.1 - 9.8e-05 22.1 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Sema PF01403.14 KFM04519.1 - 6.2e-153 509.3 0.0 7.7e-153 509.0 0.0 1.1 1 0 0 1 1 1 1 Sema domain PSI PF01437.20 KFM04519.1 - 2.1e-05 24.5 8.3 5.1e-05 23.3 5.8 1.7 1 0 0 1 1 1 1 Plexin repeat V-set PF07686.12 KFM04519.1 - 5.1e-05 23.1 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 KFM04519.1 - 0.00029 20.9 0.0 0.0075 16.3 0.0 2.7 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.11 KFM04519.1 - 0.00035 20.3 0.0 0.00084 19.1 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM04519.1 - 0.044 13.9 0.0 0.16 12.1 0.0 1.9 1 0 0 1 1 1 0 Immunoglobulin domain Peptidase_C12 PF01088.16 KFM04520.1 - 1.4e-56 191.0 0.0 2.8e-56 190.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Nucleo_P87 PF07267.6 KFM04520.1 - 0.063 11.9 8.4 0.098 11.3 5.8 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 HAUS-augmin3 PF14932.1 KFM04521.1 - 1.2e-50 172.0 0.7 1.2e-50 172.0 0.5 3.9 3 1 1 4 4 4 1 HAUS augmin-like complex subunit 3 DUF2129 PF09902.4 KFM04521.1 - 0.38 10.5 1.6 0.55 10.0 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2129) CENP-Q PF13094.1 KFM04521.1 - 0.94 9.4 38.9 0.94 9.4 3.9 4.3 4 0 0 4 4 4 0 CENP-Q, a CENPA-CAD centromere complex subunit CNH PF00780.17 KFM04522.1 - 2e-74 250.4 0.3 3.3e-74 249.7 0.2 1.4 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.20 KFM04522.1 - 2.2e-58 197.4 0.0 3.1e-58 196.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM04522.1 - 4.8e-37 127.4 0.0 7.6e-37 126.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM04522.1 - 0.012 14.6 0.1 0.028 13.4 0.0 1.6 2 0 0 2 2 2 0 Kinase-like RasGEF PF00617.14 KFM04523.1 - 1.2e-51 175.1 0.6 2.6e-51 174.0 0.4 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KFM04523.1 - 3.7e-31 107.3 0.3 1.2e-30 105.6 0.0 2.1 2 0 0 2 2 2 1 RasGEF N-terminal motif RhoGEF PF00621.15 KFM04523.1 - 1.4e-17 64.1 0.2 1.4e-17 64.1 0.1 2.4 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.24 KFM04523.1 - 2.7e-13 50.0 0.2 2.3e-12 47.0 0.0 2.8 3 0 0 3 3 3 1 PH domain Histone PF00125.19 KFM04523.1 - 2.7e-12 46.6 0.0 8.4e-12 45.0 0.0 1.9 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PH_10 PF15411.1 KFM04523.1 - 0.00024 21.2 0.0 0.00076 19.6 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain Herpes_UL92 PF03048.9 KFM04523.1 - 0.0069 15.9 0.2 0.052 13.1 0.0 2.5 3 0 0 3 3 3 1 UL92 family TraU PF06834.6 KFM04524.1 - 0.068 12.2 0.1 0.1 11.6 0.1 1.2 1 0 0 1 1 1 0 TraU protein RhoGEF PF00621.15 KFM04525.1 - 8.7e-18 64.8 3.4 1.6e-17 63.9 2.3 1.4 1 1 0 1 1 1 1 RhoGEF domain MORN PF02493.15 KFM04526.1 - 7e-08 31.7 0.4 4.4e-07 29.2 0.1 2.1 2 0 0 2 2 2 1 MORN repeat RWD PF05773.17 KFM04527.1 - 1.3e-21 76.6 0.0 4.3e-21 74.9 0.0 2.0 1 0 0 1 1 1 1 RWD domain OB_NTP_bind PF07717.11 KFM04527.1 - 7.1e-20 70.9 0.0 1.9e-19 69.5 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KFM04527.1 - 1.6e-19 69.7 0.1 1e-18 67.2 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KFM04527.1 - 1e-12 47.7 0.0 3.6e-12 45.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFM04527.1 - 2.1e-10 40.3 0.2 8.2e-10 38.4 0.2 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KFM04527.1 - 0.00036 20.6 0.1 0.0018 18.4 0.1 2.2 1 0 0 1 1 1 1 AAA domain zf-CCCH PF00642.19 KFM04527.1 - 0.00066 19.2 5.6 0.00066 19.2 3.9 1.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) T2SE PF00437.15 KFM04527.1 - 0.0011 17.9 0.0 0.0024 16.7 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Arch_ATPase PF01637.13 KFM04527.1 - 0.0039 16.9 0.0 0.021 14.5 0.0 2.1 2 0 0 2 2 2 1 Archaeal ATPase UBA PF00627.26 KFM04527.1 - 0.011 15.5 0.0 0.032 14.1 0.0 1.8 1 0 0 1 1 1 0 UBA/TS-N domain AAA_14 PF13173.1 KFM04527.1 - 0.016 15.1 0.3 0.22 11.4 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KFM04527.1 - 0.058 13.1 0.1 0.16 11.7 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 KFM04527.1 - 0.068 12.5 0.0 0.32 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 KFM04527.1 - 0.12 11.8 1.7 0.12 11.8 0.0 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase zf-CCCH_2 PF14608.1 KFM04527.1 - 0.17 11.9 4.5 0.43 10.6 3.1 1.7 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type DUF3347 PF11827.3 KFM04527.1 - 0.35 10.8 5.1 0.2 11.6 1.7 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF3347) AAA_11 PF13086.1 KFM04527.1 - 2.3 7.7 9.3 0.28 10.7 0.1 3.3 3 1 0 3 3 3 0 AAA domain RRM_1 PF00076.17 KFM04528.1 - 1.1e-15 57.0 0.0 1.5e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM04528.1 - 9.8e-10 38.1 0.0 1.4e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM04528.1 - 3.7e-09 36.4 0.0 5.5e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_3 PF13917.1 KFM04528.1 - 0.00036 20.1 2.3 0.00096 18.8 1.6 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 KFM04528.1 - 0.00051 19.8 6.1 0.001 18.8 4.2 1.5 1 0 0 1 1 1 1 Zinc knuckle Gemin6 PF06372.7 KFM04529.1 - 1e-67 226.6 0.5 1.1e-67 226.4 0.3 1.0 1 0 0 1 1 1 1 Gemin6 protein RRM_1 PF00076.17 KFM04530.1 - 5.1e-16 58.0 0.0 7.3e-16 57.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM04530.1 - 8.9e-10 38.4 0.0 1.4e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM04530.1 - 1.9e-09 37.2 0.0 2.7e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_3 PF13917.1 KFM04530.1 - 0.0004 20.0 2.3 0.0011 18.6 1.6 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 KFM04530.1 - 0.00058 19.6 6.1 0.0011 18.7 4.2 1.4 1 0 0 1 1 1 1 Zinc knuckle Aldose_epim PF01263.15 KFM04531.1 - 1.3e-98 329.8 0.0 1.5e-98 329.6 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase RRM_5 PF13893.1 KFM04532.1 - 6.3e-37 125.2 7.4 2.3e-16 59.3 0.1 4.3 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM04532.1 - 2.3e-23 81.9 0.9 5e-12 45.6 0.0 3.6 4 0 0 4 4 4 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFM04532.1 - 2.3e-16 59.1 1.9 4.2e-07 29.4 0.0 4.6 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFM04532.1 - 0.0034 17.2 0.0 0.012 15.4 0.0 1.9 2 0 0 2 2 2 1 RNA binding motif Limkain-b1 PF11608.3 KFM04532.1 - 0.016 14.9 0.0 0.53 10.0 0.0 2.7 3 0 0 3 3 3 0 Limkain b1 GBP PF02263.14 KFM04533.1 - 1.4e-101 338.8 0.1 1.9e-101 338.4 0.0 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.9 KFM04533.1 - 2.3e-07 30.3 0.1 4.9e-07 29.2 0.1 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain DEAD PF00270.24 KFM04534.1 - 3.7e-41 140.4 0.4 8.4e-41 139.2 0.2 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFM04534.1 - 7.4e-28 96.2 0.0 1.8e-27 94.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KFM04534.1 - 0.00048 19.8 0.1 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 KFM04534.1 - 0.0012 18.6 0.1 0.0027 17.5 0.1 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KFM04534.1 - 0.0013 18.4 0.0 0.0029 17.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF1253 PF06862.7 KFM04534.1 - 0.022 13.1 0.0 0.37 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) AAA_22 PF13401.1 KFM04534.1 - 0.038 14.1 0.2 0.14 12.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.9 KFM04534.1 - 0.12 12.1 0.2 0.38 10.4 0.0 2.1 1 1 1 2 2 2 0 Flavivirus DEAD domain Ldh_1_N PF00056.18 KFM04535.1 - 0.0083 15.9 0.4 0.016 14.9 0.2 1.6 1 1 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain DUF2922 PF11148.3 KFM04535.1 - 0.075 12.6 0.1 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) Pox_A11 PF05061.8 KFM04535.1 - 0.13 11.3 6.4 0.16 11.0 4.4 1.1 1 0 0 1 1 1 0 Poxvirus A11 Protein PorB PF11565.3 KFM04535.1 - 0.4 10.8 2.8 11 6.2 0.4 2.7 1 1 1 2 2 2 0 Alpha helical Porin B Sec2p PF06428.6 KFM04535.1 - 1.2 9.0 25.2 0.046 13.5 4.5 3.4 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p DIT1_PvcA PF05141.7 KFM04535.1 - 1.8 7.8 8.0 2.7 7.2 5.5 1.5 1 1 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein DUF4407 PF14362.1 KFM04535.1 - 3.1 6.6 21.0 3.9 6.3 14.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF87 PF01935.12 KFM04535.1 - 8.4 6.1 7.6 6.2 6.5 4.2 1.5 1 1 0 1 1 1 0 Domain of unknown function DUF87 HrpB7 PF09486.5 KFM04535.1 - 9.3 6.1 28.2 25 4.7 17.8 2.7 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Sec20 PF03908.8 KFM04535.1 - 9.5 6.0 9.1 0.75 9.5 1.1 2.5 1 1 2 3 3 3 0 Sec20 zf-C4H2 PF10146.4 KFM04535.1 - 9.7 6.1 14.7 12 5.8 9.8 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein Exonuc_VII_L PF02601.10 KFM04535.1 - 10 5.2 20.1 15 4.6 13.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Sld5 PF05916.6 KFM04536.1 - 0.00031 20.9 0.4 0.0016 18.6 0.0 2.1 2 1 0 2 2 2 1 GINS complex protein Calx-beta PF03160.9 KFM04537.1 - 3.2e-62 206.7 5.9 1.7e-35 120.9 0.5 2.6 2 0 0 2 2 2 2 Calx-beta domain Na_Ca_ex PF01699.19 KFM04537.1 - 6.8e-62 207.1 23.3 1.1e-34 119.0 4.8 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DnaG_DnaB_bind PF08278.6 KFM04537.1 - 0.14 12.3 2.3 0.31 11.2 1.6 1.5 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding Ribosomal_S5_C PF03719.10 KFM04539.1 - 4.9e-21 73.7 0.1 9.8e-21 72.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 KFM04539.1 - 9.4e-12 44.5 1.8 2.6e-11 43.0 1.2 1.8 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain YbfN PF13982.1 KFM04539.1 - 0.08 13.1 0.3 0.22 11.6 0.1 1.8 2 0 0 2 2 2 0 YbfN-like lipoprotein MARVEL PF01284.18 KFM04540.1 - 0.00097 18.9 5.0 0.0011 18.7 3.5 1.2 1 0 0 1 1 1 1 Membrane-associating domain Acetyltransf_1 PF00583.19 KFM04541.1 - 6.3e-14 51.7 0.1 8e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KFM04541.1 - 3.8e-08 32.9 0.1 5.2e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KFM04541.1 - 7.3e-07 29.2 0.0 9e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFM04541.1 - 9.1e-06 25.7 0.0 1.1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFM04541.1 - 0.0015 18.3 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SQS_PSY PF00494.14 KFM04541.1 - 0.048 12.9 0.0 0.068 12.4 0.0 1.1 1 0 0 1 1 1 0 Squalene/phytoene synthase EF-hand_1 PF00036.27 KFM04542.1 - 3.6e-21 72.7 8.3 1.6e-07 30.1 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 KFM04542.1 - 3.8e-19 68.0 0.9 3.4e-11 42.5 0.0 2.5 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 KFM04542.1 - 3.8e-19 66.7 3.6 5.6e-06 25.8 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 KFM04542.1 - 5.2e-18 64.9 2.5 4.3e-10 39.5 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KFM04542.1 - 1.2e-16 59.1 6.5 4.9e-06 25.6 0.0 4.4 4 1 1 5 5 5 3 EF hand SPARC_Ca_bdg PF10591.4 KFM04542.1 - 5.9e-07 29.5 0.0 0.0034 17.4 0.0 2.5 1 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFM04542.1 - 0.00017 21.2 0.3 0.18 11.5 0.0 2.5 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 KFM04542.1 - 0.0071 15.9 0.3 4.9 6.9 0.0 3.8 5 0 0 5 5 5 1 EF hand VCBS PF13517.1 KFM04542.1 - 0.049 13.9 0.1 16 5.9 0.0 3.1 3 0 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella HS1_rep PF02218.10 KFM04543.1 - 4.7e-61 202.3 44.4 6.4e-18 64.3 3.2 5.3 6 0 0 6 6 6 4 Repeat in HS1/Cortactin SH3_9 PF14604.1 KFM04543.1 - 1.1e-17 63.3 0.2 2.3e-17 62.2 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM04543.1 - 4.8e-16 57.8 0.2 1e-15 56.8 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFM04543.1 - 9.3e-09 34.6 0.0 2.3e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain NDK PF00334.14 KFM04544.1 - 4.4e-32 110.7 0.0 5.6e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Ras PF00071.17 KFM04545.1 - 6.4e-27 93.9 0.2 7.9e-27 93.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM04545.1 - 2.9e-12 47.1 0.0 5.5e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM04545.1 - 2.9e-06 26.6 0.0 4.7e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFM04545.1 - 2.5e-05 23.8 0.1 5.6e-05 22.6 0.0 1.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFM04545.1 - 0.00036 19.7 0.1 0.0007 18.8 0.1 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GH-E PF14410.1 KFM04545.1 - 0.01 15.9 0.3 3.4 7.8 0.0 2.4 2 0 0 2 2 2 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues ATP_bind_1 PF03029.12 KFM04545.1 - 0.022 14.2 0.2 0.035 13.6 0.1 1.4 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein Trypsin PF00089.21 KFM04546.1 - 3.6e-70 235.9 1.6 4e-70 235.8 1.1 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 KFM04546.1 - 4.7e-05 22.7 0.5 0.00012 21.4 0.1 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 KFM04546.1 - 8.4e-05 22.5 0.0 0.00014 21.8 0.0 1.4 1 1 0 1 1 1 1 Trypsin-like peptidase domain Ank_2 PF12796.2 KFM04548.1 - 4.4e-20 71.8 4.1 2.1e-10 40.7 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFM04548.1 - 4.5e-19 68.0 6.2 4.6e-07 29.8 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFM04548.1 - 1.5e-18 66.7 1.7 1.8e-07 31.4 0.2 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 KFM04548.1 - 2.8e-18 64.7 8.7 1.5e-05 24.5 0.1 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.1 KFM04548.1 - 8.3e-12 44.1 8.2 0.0016 18.5 0.0 5.1 5 1 0 5 5 5 3 Ankyrin repeat PDZ PF00595.19 KFM04549.1 - 1e-07 32.0 0.0 3.3e-07 30.3 0.0 1.9 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) 2C_adapt PF08793.5 KFM04549.1 - 0.13 12.1 0.0 0.99 9.3 0.0 2.2 2 0 0 2 2 2 0 2-cysteine adaptor domain SH3_9 PF14604.1 KFM04550.1 - 1.7e-14 53.1 0.1 2.9e-14 52.3 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM04550.1 - 7.6e-08 31.6 0.0 1.3e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain PID PF00640.18 KFM04550.1 - 1.7e-07 31.3 0.3 4e-06 26.8 0.0 2.9 3 1 0 3 3 3 1 Phosphotyrosine interaction domain (PTB/PID) SH3_2 PF07653.12 KFM04550.1 - 0.00084 18.7 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Muted PF14942.1 KFM04551.1 - 1.7 8.5 5.5 1.5 8.6 2.7 1.6 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein YlbD_coat PF14071.1 KFM04551.1 - 2.4 8.2 4.9 1.1 9.3 1.0 2.1 2 0 0 2 2 2 0 Putative coat protein Pkinase PF00069.20 KFM04552.1 - 3.2e-72 242.8 0.1 1.6e-71 240.4 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM04552.1 - 3.3e-34 118.1 0.0 8e-34 116.8 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM04552.1 - 0.00042 19.3 0.0 0.01 14.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Med1 PF10744.4 KFM04553.1 - 3.6e-104 348.6 0.1 1.8e-103 346.3 0.0 2.1 2 0 0 2 2 2 1 Mediator of RNA polymerase II transcription subunit 1 WbqC PF08889.6 KFM04553.1 - 0.36 10.2 0.0 0.75 9.2 0.0 1.5 1 0 0 1 1 1 0 WbqC-like protein family LRR_6 PF13516.1 KFM04554.1 - 5.6e-22 75.2 29.4 0.0053 16.6 0.0 11.4 11 1 0 11 11 11 6 Leucine Rich repeat LRR_4 PF12799.2 KFM04554.1 - 2.9e-15 55.4 13.2 0.016 14.8 0.4 6.6 5 1 1 6 6 6 5 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KFM04554.1 - 1.3e-13 50.4 0.6 4.6e-13 48.6 0.4 2.0 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 KFM04554.1 - 8e-13 47.9 19.2 0.00019 21.1 2.7 5.9 3 3 2 5 5 5 5 Leucine rich repeat LRR_1 PF00560.28 KFM04554.1 - 1.3e-11 42.8 22.8 1.4 9.2 0.1 11.7 11 1 0 11 11 11 3 Leucine Rich Repeat F-box PF00646.28 KFM04554.1 - 1.7e-07 30.6 0.7 1.7e-07 30.6 0.5 2.5 2 0 0 2 2 2 1 F-box domain LRR_7 PF13504.1 KFM04554.1 - 5.6e-07 28.7 21.1 0.95 9.9 0.0 10.4 11 0 0 11 11 11 2 Leucine rich repeat Ribosomal_L19e PF01280.15 KFM04555.1 - 4.1e-63 211.5 14.3 4.1e-63 211.5 9.9 2.0 1 1 1 2 2 2 1 Ribosomal protein L19e Ribosomal_L14 PF00238.14 KFM04556.1 - 2.8e-29 101.3 0.1 3e-29 101.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e CWC25 PF12542.3 KFM04557.1 - 2.8e-20 72.5 0.1 2.8e-20 72.5 0.0 4.6 4 1 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 KFM04557.1 - 2.8e-15 56.0 13.5 2.8e-15 56.0 9.4 6.6 6 1 1 7 7 7 1 N-terminal domain of CBF1 interacting co-repressor CIR tRNA-synt_1c PF00749.16 KFM04557.1 - 0.00095 17.9 4.4 0.00095 17.9 3.1 3.2 4 0 0 4 4 4 1 tRNA synthetases class I (E and Q), catalytic domain PIP5K PF01504.13 KFM04558.1 - 7.2e-75 251.3 0.0 8.7e-75 251.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Proteasome PF00227.21 KFM04559.1 - 5.7e-42 143.1 0.0 6.4e-42 142.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Rad60-SLD PF11976.3 KFM04560.1 - 0.05 13.2 0.0 0.081 12.6 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like zf-HC5HC2H_2 PF13832.1 KFM04561.1 - 4.1e-30 104.0 11.3 4.1e-30 104.0 7.8 1.8 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KFM04561.1 - 3.8e-19 68.6 10.4 3.8e-19 68.6 7.2 2.8 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.1 KFM04561.1 - 0.00086 18.5 1.1 0.00086 18.5 0.7 2.9 4 0 0 4 4 4 1 PHD-finger HALZ PF02183.13 KFM04561.1 - 2.9 7.6 10.2 0.06 13.0 1.3 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF2180 PF09947.4 KFM04561.1 - 3.1 7.6 9.5 2.4 7.9 3.3 2.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) SOCS_box PF07525.11 KFM04563.1 - 5e-13 48.6 3.3 5e-13 48.6 2.3 1.8 2 0 0 2 2 2 1 SOCS box SH2 PF00017.19 KFM04563.1 - 2.2e-09 36.9 0.0 6.1e-09 35.5 0.0 1.8 1 1 1 2 2 2 1 SH2 domain Tim44 PF04280.10 KFM04564.1 - 1.7e-27 96.2 0.0 2.2e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Tim44-like domain MBA1 PF07961.6 KFM04564.1 - 0.0012 17.7 0.0 0.0018 17.1 0.0 1.3 1 0 0 1 1 1 1 MBA1-like protein ChaB PF06150.7 KFM04564.1 - 0.051 13.3 0.1 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 ChaB Peptidase_M1 PF01433.15 KFM04565.1 - 2.5e-140 467.9 0.0 3.4e-140 467.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 KFM04565.1 - 1.6e-62 211.6 0.0 3.5e-62 210.5 0.0 1.6 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KFM04565.1 - 1.7e-22 79.8 0.3 3.4e-22 78.8 0.2 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily tRNA_anti-codon PF01336.20 KFM04565.1 - 0.042 13.7 0.0 0.17 11.7 0.0 2.0 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain NatB_MDM20 PF09797.4 KFM04565.1 - 0.19 10.4 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit HEAT_EZ PF13513.1 KFM04566.1 - 3.7e-18 65.4 1.0 1.6e-09 37.9 0.0 7.5 7 2 2 9 9 9 3 HEAT-like repeat HEAT PF02985.17 KFM04566.1 - 5.5e-18 63.3 8.8 4.1e-05 23.3 0.0 9.6 10 0 0 10 10 10 4 HEAT repeat HEAT_2 PF13646.1 KFM04566.1 - 3.5e-15 56.0 0.3 1.5e-05 25.1 0.0 5.7 2 1 5 8 8 8 6 HEAT repeats IBN_N PF03810.14 KFM04566.1 - 1.2e-12 47.6 0.4 1.4e-11 44.1 0.0 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain Arm PF00514.18 KFM04566.1 - 8.5e-10 38.0 4.7 0.0016 18.2 0.0 6.2 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 KFM04566.1 - 0.00015 21.2 5.7 0.4 9.9 0.0 4.3 3 1 1 4 4 4 2 CLASP N terminal UME PF08064.8 KFM04566.1 - 0.021 14.7 2.1 4.9 7.1 0.0 4.5 4 1 0 4 4 4 0 UME (NUC010) domain ABC_membrane PF00664.18 KFM04567.1 - 1.1e-126 421.8 21.5 2.3e-70 237.1 2.5 2.6 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFM04567.1 - 2.4e-72 241.6 0.6 4.2e-35 121.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KFM04567.1 - 6.6e-12 45.1 1.4 1.8e-05 24.1 0.1 3.1 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 KFM04567.1 - 4.9e-08 32.3 0.0 0.0047 16.1 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_21 PF13304.1 KFM04567.1 - 8.8e-08 32.4 0.1 0.029 14.3 0.0 4.1 2 2 1 3 3 3 2 AAA domain AAA_16 PF13191.1 KFM04567.1 - 3.2e-07 30.5 0.4 0.0047 16.9 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KFM04567.1 - 2.2e-06 27.1 0.7 0.0063 16.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 KFM04567.1 - 6.3e-06 26.3 0.1 0.048 13.8 0.0 3.1 2 1 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 KFM04567.1 - 1.7e-05 23.6 1.6 0.084 11.4 0.0 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_17 PF13207.1 KFM04567.1 - 4.8e-05 24.1 0.0 0.12 13.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KFM04567.1 - 4.8e-05 22.5 0.5 0.017 14.2 0.0 2.8 3 0 0 3 3 3 1 Zeta toxin AAA_30 PF13604.1 KFM04567.1 - 0.0002 21.0 0.2 1.2 8.6 0.0 3.6 3 1 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 KFM04567.1 - 0.00097 19.0 0.4 0.82 9.6 0.0 3.3 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 KFM04567.1 - 0.002 18.1 0.0 8.2 6.3 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 KFM04567.1 - 0.0028 17.5 0.0 2.2 8.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KFM04567.1 - 0.0029 17.0 5.8 0.42 10.0 0.9 3.4 3 1 0 3 3 2 1 AAA domain SRP54 PF00448.17 KFM04567.1 - 0.0038 16.6 0.0 0.63 9.4 0.0 2.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_10 PF12846.2 KFM04567.1 - 0.0042 16.5 1.1 5.8 6.2 0.0 3.3 3 0 0 3 3 3 0 AAA-like domain DUF87 PF01935.12 KFM04567.1 - 0.0044 16.8 0.2 3 7.5 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 MobB PF03205.9 KFM04567.1 - 0.011 15.4 0.1 6.2 6.5 0.0 3.8 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B G-alpha PF00503.15 KFM04567.1 - 0.017 13.8 0.0 4.6 5.8 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit ATP-synt_ab PF00006.20 KFM04567.1 - 0.028 13.9 0.5 2.9 7.3 0.1 2.6 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.17 KFM04567.1 - 0.037 14.2 0.0 5.7 7.1 0.0 3.0 2 0 0 2 2 2 0 RNA helicase APS_kinase PF01583.15 KFM04567.1 - 0.038 13.6 0.0 2.5 7.7 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_18 PF13238.1 KFM04567.1 - 0.038 14.2 0.0 21 5.4 0.0 3.1 3 0 0 3 3 2 0 AAA domain DUF2269 PF10027.4 KFM04567.1 - 0.058 13.1 6.1 0.26 11.0 1.9 3.0 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2269) Rad17 PF03215.10 KFM04567.1 - 0.088 11.4 0.0 0.53 8.9 0.0 2.0 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein MMR_HSR1 PF01926.18 KFM04567.1 - 0.13 12.2 0.3 6.9 6.6 0.0 2.9 2 2 0 2 2 2 0 50S ribosome-binding GTPase PAP2 PF01569.16 KFM04568.1 - 9.5e-14 51.1 6.6 9.5e-14 51.1 4.6 1.9 2 0 0 2 2 2 1 PAP2 superfamily DUF4117 PF13491.1 KFM04568.1 - 0.054 12.9 7.0 0.19 11.1 4.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4117) Spindle_Spc25 PF08234.7 KFM04569.1 - 1.5e-24 85.7 0.2 1.5e-24 85.7 0.1 1.9 2 1 0 2 2 2 1 Chromosome segregation protein Spc25 Spc7 PF08317.6 KFM04569.1 - 6.7e-05 21.7 17.2 8.9e-05 21.2 11.9 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Tox-ODYAM1 PF15642.1 KFM04569.1 - 0.014 14.0 9.4 0.024 13.2 6.5 1.4 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus SPX PF03105.14 KFM04569.1 - 0.021 14.6 7.7 0.025 14.3 5.3 1.3 1 0 0 1 1 1 0 SPX domain IFT57 PF10498.4 KFM04569.1 - 0.03 13.0 14.1 0.039 12.6 9.8 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF4201 PF13870.1 KFM04569.1 - 0.039 13.3 19.7 0.054 12.9 13.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Bacillus_HBL PF05791.6 KFM04569.1 - 0.044 13.1 12.3 0.1 11.9 7.1 2.0 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) MutS_III PF05192.13 KFM04569.1 - 0.053 13.2 1.9 0.065 12.9 1.3 1.2 1 0 0 1 1 1 0 MutS domain III Ubiquitin_2 PF14560.1 KFM04569.1 - 0.066 13.4 3.8 0.77 10.0 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin-like domain Phage_GPO PF05929.6 KFM04569.1 - 0.21 10.7 5.3 0.37 9.9 3.7 1.5 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Atg14 PF10186.4 KFM04569.1 - 0.37 9.6 15.3 0.62 8.9 10.6 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 KFM04569.1 - 0.39 8.5 9.2 0.44 8.3 6.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF745 PF05335.8 KFM04569.1 - 0.51 9.8 11.3 1 8.8 7.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF745) IncA PF04156.9 KFM04569.1 - 0.52 9.8 22.5 0.16 11.5 12.9 1.7 1 1 1 2 2 2 0 IncA protein Mnd1 PF03962.10 KFM04569.1 - 0.65 9.6 17.6 0.32 10.6 10.1 1.7 1 1 1 2 2 2 0 Mnd1 family CTNNB1_binding PF08347.6 KFM04569.1 - 0.67 10.1 8.8 1.1 9.4 6.1 1.3 1 0 0 1 1 1 0 N-terminal CTNNB1 binding Peptidase_C6 PF00851.13 KFM04569.1 - 0.72 8.4 8.4 0.95 8.0 5.8 1.1 1 0 0 1 1 1 0 Helper component proteinase CorA PF01544.13 KFM04569.1 - 1.6 7.6 11.2 4 6.3 7.2 1.9 1 1 2 3 3 3 0 CorA-like Mg2+ transporter protein DUF342 PF03961.8 KFM04569.1 - 1.7 6.9 13.9 2.4 6.4 9.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 KFM04569.1 - 1.9 7.4 18.9 2.9 6.8 13.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF445 PF04286.7 KFM04569.1 - 2.1 7.7 12.4 3.1 7.2 8.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) AATF-Che1 PF13339.1 KFM04569.1 - 2.3 8.3 13.8 0.52 10.4 6.6 2.0 1 1 0 2 2 2 0 Apoptosis antagonizing transcription factor DUF1664 PF07889.7 KFM04569.1 - 2.4 7.9 12.4 8.2 6.2 1.8 2.6 2 1 1 3 3 2 0 Protein of unknown function (DUF1664) COG5 PF10392.4 KFM04569.1 - 2.7 7.9 10.6 5.5 6.9 7.3 1.6 1 1 0 1 1 1 0 Golgi transport complex subunit 5 ALMT PF11744.3 KFM04569.1 - 2.7 6.5 7.4 4.5 5.8 5.1 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2203 PF09969.4 KFM04569.1 - 4.1 7.6 9.5 11 6.2 5.6 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Dynamin_N PF00350.18 KFM04569.1 - 6.2 6.6 11.9 96 2.7 8.2 2.3 1 1 0 1 1 1 0 Dynamin family DUF4407 PF14362.1 KFM04569.1 - 9.2 5.1 8.7 2.1 7.1 3.9 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Toxin_64 PF15542.1 KFM04569.1 - 9.5 6.8 10.3 5.9 7.5 5.1 2.0 1 1 1 2 2 2 0 Putative toxin 64 TRAM_LAG1_CLN8 PF03798.11 KFM04570.1 - 1e-36 126.3 23.8 1.2e-36 126.1 16.5 1.1 1 0 0 1 1 1 1 TLC domain Homeobox PF00046.24 KFM04570.1 - 2.2e-07 30.4 0.5 3.7e-07 29.6 0.4 1.3 1 0 0 1 1 1 1 Homeobox domain Pkinase PF00069.20 KFM04571.1 - 1.2e-56 191.7 0.0 1.5e-56 191.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM04571.1 - 1.3e-39 135.8 0.0 1.9e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM04571.1 - 0.00013 21.0 0.0 0.0002 20.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFM04571.1 - 0.043 12.8 0.0 0.063 12.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFM04571.1 - 0.093 12.4 0.0 0.19 11.4 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Galactosyl_T PF01762.16 KFM04572.1 - 8.5e-61 204.9 0.0 1.1e-60 204.6 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase LIM PF00412.17 KFM04573.1 - 1.2e-12 47.7 10.0 1.5e-12 47.3 6.9 1.2 1 0 0 1 1 1 1 LIM domain Cytochrom_C550 PF14495.1 KFM04573.1 - 0.27 10.6 1.6 0.34 10.3 1.1 1.3 1 0 0 1 1 1 0 Cytochrome c-550 domain DZR PF12773.2 KFM04573.1 - 1.4 8.7 6.8 28 4.6 4.7 2.3 1 1 0 1 1 1 0 Double zinc ribbon Ion_trans PF00520.26 KFM04574.1 - 8.7e-137 452.7 61.5 7.5e-73 244.0 10.3 4.3 4 0 0 4 4 4 3 Ion transport protein DUF3451 PF11933.3 KFM04574.1 - 9.4e-67 225.0 10.5 2e-66 224.0 7.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3451) Na_trans_assoc PF06512.8 KFM04574.1 - 4.2e-59 200.4 8.1 4.2e-59 200.4 5.6 2.6 3 0 0 3 3 3 1 Sodium ion transport-associated DICT PF10069.4 KFM04574.1 - 0.03 13.8 0.2 0.063 12.8 0.1 1.4 1 0 0 1 1 1 0 Sensory domain found in DIguanylate Cyclases & Two-component systems Neur_chan_memb PF02932.11 KFM04574.1 - 0.43 10.4 0.0 0.43 10.4 0.0 3.0 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region DUF4407 PF14362.1 KFM04574.1 - 0.54 9.1 3.8 1.2 7.9 2.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3138 PF11336.3 KFM04574.1 - 4.6 5.3 5.8 2.1 6.4 2.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Ion_trans PF00520.26 KFM04575.1 - 2.8e-52 176.9 40.6 8.4e-50 168.8 13.6 3.2 3 0 0 3 3 3 2 Ion transport protein PKD_channel PF08016.7 KFM04575.1 - 5.7e-08 31.6 21.0 7e-06 24.7 0.3 3.3 2 1 1 3 3 3 3 Polycystin cation channel IQ PF00612.22 KFM04575.1 - 0.0026 17.2 0.2 0.0056 16.2 0.2 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif Glycos_transf_2 PF00535.21 KFM04576.1 - 3.3e-30 104.9 0.0 5.8e-30 104.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 KFM04576.1 - 2.5e-25 88.9 0.6 4e-25 88.2 0.4 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.9 KFM04576.1 - 6.3e-11 41.5 0.0 2.2e-10 39.8 0.1 1.8 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFM04576.1 - 3.6e-09 36.1 0.1 2.9e-08 33.1 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.1 KFM04576.1 - 1.5e-08 34.7 0.0 2.6e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 GlcNAc PF11397.3 KFM04576.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase (GlcNAc) Glyco_trans_2_3 PF13632.1 KFM04576.1 - 0.093 12.4 0.0 0.093 12.4 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase family group 2 Spt5_N PF11942.3 KFM04577.1 - 0.0047 17.5 6.1 0.0047 17.5 4.3 4.1 4 1 1 5 5 5 1 Spt5 transcription elongation factor, acidic N-terminal Aa_trans PF01490.13 KFM04579.1 - 3e-64 217.0 30.8 3.4e-64 216.8 21.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KFM04579.1 - 0.00011 21.1 16.1 0.00011 21.1 11.2 2.2 1 1 2 3 3 3 1 Tryptophan/tyrosine permease family DUF2427 PF10348.4 KFM04579.1 - 0.23 11.0 18.4 0.1 12.2 1.8 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF2427) DUF2371 PF10177.4 KFM04579.1 - 0.47 10.3 0.0 0.47 10.3 0.0 3.1 3 1 0 3 3 3 0 Uncharacterised conserved protein (DUF2371) Cobl PF09469.5 KFM04580.1 - 2.2e-31 107.6 1.5 2.2e-31 107.6 1.1 2.5 2 0 0 2 2 2 1 Cordon-bleu ubiquitin-like domain MutS_II PF05188.12 KFM04580.1 - 0.021 14.8 0.1 1.6 8.8 0.0 2.9 2 0 0 2 2 2 0 MutS domain II TUG-UBL1 PF11470.3 KFM04580.1 - 0.069 13.0 0.3 0.81 9.6 0.1 2.5 2 0 0 2 2 2 0 GLUT4 regulating protein TUG YukD PF08817.5 KFM04580.1 - 0.1 13.2 0.1 0.4 11.2 0.0 2.1 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD DUF1860 PF08949.5 KFM04580.1 - 0.22 11.0 0.0 0.41 10.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1860) BPS PF08947.5 KFM04581.1 - 1e-27 95.4 0.3 1.8e-27 94.6 0.2 1.4 1 0 0 1 1 1 1 BPS (Between PH and SH2) SH2 PF00017.19 KFM04581.1 - 3.6e-17 61.9 0.1 8.2e-17 60.7 0.1 1.7 1 0 0 1 1 1 1 SH2 domain RA PF00788.18 KFM04581.1 - 5.5e-14 52.4 0.1 2.3e-13 50.4 0.1 2.1 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain PH PF00169.24 KFM04581.1 - 6.5e-08 32.7 0.1 1.7e-07 31.4 0.1 1.8 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 KFM04581.1 - 0.12 12.5 0.1 0.38 10.9 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain AAA PF00004.24 KFM04583.1 - 1.2e-24 86.9 0.0 2e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFM04583.1 - 8.5e-05 22.3 0.0 0.0002 21.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Vps4_C PF09336.5 KFM04583.1 - 0.00025 20.8 0.0 0.00061 19.6 0.0 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_16 PF13191.1 KFM04583.1 - 0.0057 16.6 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 KFM04583.1 - 0.024 13.7 0.0 0.04 12.9 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KFM04583.1 - 0.041 14.0 0.0 0.082 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 KFM04583.1 - 0.11 11.1 0.0 0.21 10.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Ion_trans PF00520.26 KFM04584.1 - 1.9e-20 72.9 4.1 3.4e-20 72.1 2.8 1.4 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.24 KFM04584.1 - 4.8e-14 51.9 0.0 8.4e-14 51.1 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.11 KFM04584.1 - 6.7e-12 44.9 0.0 6.7e-12 44.9 0.0 2.3 4 0 0 4 4 4 1 Ion channel Ion_trans_N PF08412.5 KFM04584.1 - 0.0057 15.9 0.2 0.02 14.1 0.1 1.9 1 0 0 1 1 1 1 Ion transport protein N-terminal OppC_N PF12911.2 KFM04584.1 - 0.034 13.4 0.9 10 5.5 0.2 2.7 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF3099 PF11298.3 KFM04584.1 - 0.082 12.6 1.1 0.36 10.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) RIG-I_C-RD PF11648.3 KFM04585.1 - 3.3e-35 120.6 2.8 3.3e-35 120.6 1.9 2.5 2 0 0 2 2 2 1 C-terminal domain of RIG-I ResIII PF04851.10 KFM04585.1 - 2.9e-18 66.3 0.0 2.9e-18 66.3 0.0 3.7 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KFM04585.1 - 2.4e-17 62.5 0.4 1.5e-16 59.9 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFM04585.1 - 7.3e-17 61.3 0.0 2.3e-16 59.7 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase CARD PF00619.16 KFM04585.1 - 2.7e-10 39.9 0.1 1.4e-06 27.9 0.0 2.6 2 0 0 2 2 2 2 Caspase recruitment domain Yippee-Mis18 PF03226.9 KFM04585.1 - 0.0038 17.2 1.7 0.015 15.3 1.2 2.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly AAA_22 PF13401.1 KFM04585.1 - 0.0064 16.6 0.7 0.037 14.1 0.0 2.6 3 1 0 3 3 3 1 AAA domain PFO_beta_C PF12367.3 KFM04585.1 - 0.033 14.1 0.5 0.21 11.5 0.4 2.4 2 0 0 2 2 2 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal DPPIV_N PF00930.16 KFM04586.1 - 1.8e-104 349.1 7.9 2.5e-104 348.6 5.5 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 KFM04586.1 - 2.5e-54 183.7 0.9 3.9e-54 183.0 0.6 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KFM04586.1 - 1e-10 41.5 0.0 2.3e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFM04586.1 - 2.1e-07 31.0 0.0 1.1e-06 28.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 KFM04586.1 - 0.00022 20.5 0.0 0.00037 19.7 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S15 PF02129.13 KFM04586.1 - 0.00026 20.5 2.1 0.0021 17.5 0.2 2.3 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) LIP PF03583.9 KFM04586.1 - 0.00063 19.0 0.3 0.0014 17.8 0.2 1.5 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_2 PF02230.11 KFM04586.1 - 0.0013 18.1 1.7 0.092 12.1 0.3 2.3 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase PAF-AH_p_II PF03403.8 KFM04586.1 - 0.0072 14.6 0.0 0.57 8.4 0.0 2.7 3 0 0 3 3 3 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_1 PF00561.15 KFM04586.1 - 0.027 14.0 0.4 0.27 10.7 0.1 2.3 1 1 1 2 2 2 0 alpha/beta hydrolase fold FSH1 PF03959.8 KFM04586.1 - 0.057 12.8 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DLH PF01738.13 KFM04586.1 - 0.1 11.8 0.9 0.48 9.6 0.7 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family Hormone_2 PF00123.15 KFM04587.1 - 3.8e-49 164.1 5.2 1.4e-16 59.9 0.5 3.3 3 0 0 3 3 3 3 Peptide hormone SBP_bac_8 PF13416.1 KFM04587.1 - 0.00097 18.9 0.1 6.6 6.3 0.0 3.1 3 0 0 3 3 3 2 Bacterial extracellular solute-binding protein mIF3 PF14877.1 KFM04587.1 - 0.072 12.4 0.2 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial translation initiation factor HCO3_cotransp PF00955.16 KFM04588.1 - 2.3e-244 811.8 6.9 2.8e-244 811.4 4.8 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.8 KFM04588.1 - 2e-103 345.4 0.0 2.9e-103 344.8 0.0 1.2 1 0 0 1 1 1 1 Band 3 cytoplasmic domain JAB PF01398.16 KFM04590.1 - 2.5e-35 120.6 0.1 7.2e-35 119.1 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KFM04590.1 - 2.8e-31 107.9 4.7 5.8e-31 106.9 3.2 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 KFM04590.1 - 8.2e-08 31.7 0.0 1.3e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain GPAT_N PF14829.1 KFM04590.1 - 0.028 14.1 1.4 0.044 13.4 0.1 1.9 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase N-terminal RRM_1 PF00076.17 KFM04592.1 - 5.9e-33 112.3 0.0 3e-16 58.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM04592.1 - 4.9e-26 90.5 0.0 1.6e-12 47.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM04592.1 - 8.4e-14 51.1 0.0 1.3e-06 28.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cytadhesin_P30 PF07271.6 KFM04592.1 - 0.014 14.6 1.5 0.029 13.6 1.1 1.6 1 0 0 1 1 1 0 Cytadhesin P30/P32 Integrin_beta PF00362.13 KFM04593.1 - 2.5e-177 590.0 0.2 4e-177 589.3 0.1 1.3 1 0 0 1 1 1 1 Integrin, beta chain Integrin_b_cyt PF08725.6 KFM04593.1 - 9.9e-20 69.6 0.7 1.6e-19 69.0 0.5 1.3 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain EGF_2 PF07974.8 KFM04593.1 - 7.2e-05 22.8 39.8 0.00026 21.0 12.7 8.5 8 2 0 8 8 8 3 EGF-like domain hEGF PF12661.2 KFM04593.1 - 0.013 15.5 2.6 0.013 15.5 1.8 6.4 7 0 0 7 7 7 0 Human growth factor-like EGF DUF2975 PF11188.3 KFM04593.1 - 0.052 13.2 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) DUF2970 PF11174.3 KFM04593.1 - 0.12 11.9 0.1 0.26 10.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) Lectin_C PF00059.16 KFM04594.1 - 4.1e-123 403.4 57.5 1.6e-18 67.3 0.5 8.8 8 0 0 8 8 8 8 Lectin C-type domain fn2 PF00040.14 KFM04594.1 - 2.4e-16 59.4 13.2 1.3e-15 57.1 9.1 2.4 1 0 0 1 1 1 1 Fibronectin type II domain Herpes_UL45 PF05473.7 KFM04594.1 - 4.2e-14 52.4 8.0 0.0006 19.3 0.1 7.1 5 2 1 6 6 6 5 UL45 protein Xlink PF00193.12 KFM04594.1 - 0.00022 21.2 4.9 1.2 9.2 0.0 6.5 7 0 0 7 7 7 1 Extracellular link domain gp32 PF08804.5 KFM04594.1 - 0.013 15.6 9.4 0.14 12.2 0.0 3.4 3 0 0 3 3 3 0 gp32 DNA binding protein like Lectin_C PF00059.16 KFM04595.1 - 2.9e-134 439.2 82.8 2.3e-18 66.7 0.5 12.0 12 1 1 13 13 13 10 Lectin C-type domain fn2 PF00040.14 KFM04595.1 - 1.1e-15 57.3 7.7 2.5e-15 56.2 3.6 2.9 2 0 0 2 2 2 1 Fibronectin type II domain Herpes_UL45 PF05473.7 KFM04595.1 - 1.3e-09 37.7 20.7 0.17 11.3 0.0 9.6 10 2 1 11 11 11 5 UL45 protein FixQ PF05545.6 KFM04595.1 - 0.41 10.3 4.0 0.96 9.1 2.8 1.6 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ HCO3_cotransp PF00955.16 KFM04596.1 - 5.4e-231 767.6 26.4 2.6e-139 465.2 8.3 2.3 1 1 1 2 2 2 2 HCO3- transporter family Band_3_cyto PF07565.8 KFM04596.1 - 4.8e-105 350.7 0.3 4.8e-105 350.7 0.2 2.6 3 0 0 3 3 3 1 Band 3 cytoplasmic domain PTS_EIIA_2 PF00359.17 KFM04596.1 - 6.2e-05 22.7 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Paf1 PF03985.8 KFM04596.1 - 0.0017 17.1 15.1 0.0017 17.1 10.4 1.9 2 0 0 2 2 2 1 Paf1 Daxx PF03344.10 KFM04596.1 - 1.1 7.6 19.6 0.035 12.5 8.7 2.0 2 0 0 2 2 2 0 Daxx Family LRR_4 PF12799.2 KFM04597.1 - 3.1e-15 55.3 19.4 1e-07 31.4 0.9 5.1 2 1 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM04597.1 - 1.6e-09 37.3 29.0 2.3e-06 27.2 3.1 3.8 2 1 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 KFM04597.1 - 9.6e-06 24.9 14.7 1.9 8.8 0.0 7.0 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_9 PF14580.1 KFM04597.1 - 0.00073 19.1 1.4 0.0017 17.9 0.9 1.6 1 1 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.1 KFM04597.1 - 0.013 15.5 13.5 3.3 8.0 0.1 6.5 5 1 1 6 6 6 0 Leucine Rich repeat BESS PF02944.15 KFM04597.1 - 4.3 6.9 7.1 0.6 9.7 0.1 2.8 3 0 0 3 3 3 0 BESS motif LRR_7 PF13504.1 KFM04597.1 - 5.7 7.5 18.1 6.9 7.3 0.1 7.1 6 1 1 7 7 7 0 Leucine rich repeat Connexin PF00029.14 KFM04598.1 - 1.9e-51 172.6 0.3 2.9e-51 172.0 0.2 1.2 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 KFM04598.1 - 8.7e-22 76.7 0.6 8.7e-22 76.7 0.4 2.5 3 0 0 3 3 3 1 Gap junction channel protein cysteine-rich domain TGF_beta PF00019.15 KFM04599.1 - 3.1e-17 62.7 2.2 2e-12 47.2 0.2 2.4 1 1 1 2 2 2 2 Transforming growth factor beta like domain DUF4203 PF13886.1 KFM04600.1 - 1.9e-58 197.3 34.7 2.3e-58 197.1 24.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) SlyX PF04102.7 KFM04600.1 - 0.82 10.0 4.1 1.7 9.0 2.8 1.4 1 0 0 1 1 1 0 SlyX DUF2755 PF10954.3 KFM04600.1 - 1.2 8.8 9.5 0.43 10.3 3.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2755) IBV_3C PF03620.8 KFM04600.1 - 1.3 8.9 6.0 0.21 11.5 0.6 2.3 3 0 0 3 3 3 0 IBV 3C protein CHGN PF05679.11 KFM04601.1 - 8.2e-177 588.8 0.6 9.6e-177 588.6 0.4 1.0 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.11 KFM04601.1 - 1.3e-07 31.0 0.0 2.9e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 Fringe-like ASC PF00858.19 KFM04602.1 - 3.9e-148 493.7 0.0 4.7e-148 493.4 0.0 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel ASC PF00858.19 KFM04603.1 - 8.8e-26 90.5 0.0 9.4e-26 90.4 0.0 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Rootletin PF15035.1 KFM04604.1 - 0.05 13.5 10.6 0.07 13.1 7.3 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion 5_nucleotid PF05761.9 KFM04604.1 - 0.087 11.3 0.4 0.11 11.0 0.3 1.0 1 0 0 1 1 1 0 5' nucleotidase family YlqD PF11068.3 KFM04604.1 - 0.11 12.5 3.0 0.14 12.2 2.1 1.2 1 0 0 1 1 1 0 YlqD protein APG6 PF04111.7 KFM04604.1 - 1.6 7.7 6.2 2 7.3 4.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 RhoGAP PF00620.22 KFM04605.1 - 7.1e-37 126.3 0.0 8.9e-37 126.0 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.17 KFM04605.1 - 3.6e-06 26.6 4.6 8.3e-06 25.4 3.2 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 KFM04605.1 - 0.0083 15.8 5.7 0.02 14.5 4.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 C1_3 PF07649.7 KFM04605.1 - 0.18 11.8 1.3 0.75 9.8 0.9 2.1 1 1 0 1 1 1 0 C1-like domain PHD PF00628.24 KFM04605.1 - 0.36 10.5 5.8 0.82 9.4 4.0 1.6 1 0 0 1 1 1 0 PHD-finger NTP_transferase PF00483.18 KFM04606.1 - 3.6e-15 55.9 0.0 5.4e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 KFM04606.1 - 1.4e-07 30.6 11.5 7.1e-07 28.4 1.0 4.2 2 1 2 4 4 4 1 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.7 KFM04606.1 - 0.0019 16.8 0.3 0.16 10.5 0.1 2.1 2 0 0 2 2 2 2 L-fucokinase Hexapep_2 PF14602.1 KFM04606.1 - 0.035 13.6 0.5 0.035 13.6 0.3 2.4 4 0 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase Pkinase PF00069.20 KFM04607.1 - 4.6e-23 81.6 0.9 4.8e-23 81.6 0.6 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM04607.1 - 2.8e-14 52.8 0.3 3.2e-14 52.6 0.2 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM04607.1 - 0.028 13.3 0.1 0.032 13.1 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Propeptide_C25 PF08126.6 KFM04607.1 - 0.13 11.2 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Propeptide_C25 I-set PF07679.11 KFM04608.1 - 2.7e-19 68.7 0.0 3.2e-19 68.5 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM04608.1 - 4.2e-08 33.2 0.0 5.1e-08 32.9 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFM04608.1 - 4.8e-07 29.6 0.0 1.8e-06 27.8 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 KFM04608.1 - 1.4e-06 28.2 0.0 1.9e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFM04608.1 - 0.0026 18.2 0.0 0.017 15.6 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin domain C1-set PF07654.10 KFM04608.1 - 0.033 14.1 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin C1-set domain BiPBP_C PF06832.7 KFM04608.1 - 0.077 12.9 0.0 0.17 11.8 0.0 1.6 1 1 1 2 2 2 0 Penicillin-Binding Protein C-terminus Family Filament PF00038.16 KFM04609.1 - 2.1e-116 388.7 46.3 2.5e-116 388.5 32.1 1.0 1 0 0 1 1 1 1 Intermediate filament protein Filament_head PF04732.9 KFM04609.1 - 5.2e-22 78.3 11.7 1.2e-21 77.1 7.3 2.1 2 0 0 2 2 2 1 Intermediate filament head (DNA binding) region Reo_sigmaC PF04582.7 KFM04609.1 - 0.00019 20.7 4.2 0.3 10.2 0.3 3.1 1 1 1 3 3 3 2 Reovirus sigma C capsid protein HR1 PF02185.11 KFM04609.1 - 0.0036 17.0 12.4 0.0036 17.0 8.6 5.4 4 2 1 5 5 5 2 Hr1 repeat Myosin_tail_1 PF01576.14 KFM04609.1 - 0.0058 14.4 46.7 0.03 12.0 31.9 2.7 1 1 0 1 1 1 1 Myosin tail WEMBL PF05701.6 KFM04609.1 - 0.0097 14.4 32.6 0.11 10.9 8.4 2.4 1 1 1 2 2 2 2 Weak chloroplast movement under blue light DUF1664 PF07889.7 KFM04609.1 - 0.01 15.6 1.8 0.01 15.6 1.2 3.7 2 1 2 4 4 4 1 Protein of unknown function (DUF1664) DUF4140 PF13600.1 KFM04609.1 - 0.06 13.8 33.0 0.12 12.7 1.9 5.6 1 1 4 5 5 5 0 N-terminal domain of unknown function (DUF4140) DUF3510 PF12022.3 KFM04609.1 - 0.14 12.2 8.1 1.8 8.6 0.3 4.0 2 2 1 3 3 3 0 Domain of unknown function (DUF3510) TPR_MLP1_2 PF07926.7 KFM04609.1 - 0.16 11.7 37.2 2.4 7.8 0.1 4.7 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.7 KFM04609.1 - 0.23 11.2 16.1 1.4 8.7 0.3 4.3 1 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF573 PF04504.9 KFM04609.1 - 0.34 11.2 6.1 6.5 7.1 0.2 3.6 2 2 1 3 3 3 0 Protein of unknown function, DUF573 DUF948 PF06103.6 KFM04609.1 - 0.35 10.7 10.1 0.83 9.5 0.5 4.1 2 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) MxiH PF09392.5 KFM04609.1 - 0.44 11.1 3.8 2 9.0 1.0 3.1 1 1 1 2 2 2 0 Type III secretion needle MxiH like Tropomyosin_1 PF12718.2 KFM04609.1 - 0.58 9.9 41.4 14 5.4 0.2 4.1 1 1 3 4 4 4 0 Tropomyosin like DUF812 PF05667.6 KFM04609.1 - 1.3 7.4 30.1 0.022 13.2 6.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF812) CENP-H PF05837.7 KFM04609.1 - 1.4 9.1 31.3 0.22 11.7 1.1 4.7 1 1 3 5 5 5 0 Centromere protein H (CENP-H) DUF4515 PF14988.1 KFM04609.1 - 1.7 8.2 40.3 0.098 12.3 5.5 3.1 1 1 2 3 3 2 0 Domain of unknown function (DUF4515) AAA_13 PF13166.1 KFM04609.1 - 2.1 6.7 29.7 0.13 10.7 15.0 2.2 1 1 1 2 2 2 0 AAA domain Spc7 PF08317.6 KFM04609.1 - 2.2 6.8 31.3 0.39 9.3 4.1 2.7 1 1 1 2 2 2 0 Spc7 kinetochore protein WD40_alt PF14077.1 KFM04609.1 - 2.5 7.7 11.0 18 5.0 0.9 4.6 4 1 0 4 4 3 0 Alternative WD40 repeat motif ERM PF00769.14 KFM04609.1 - 3.7 7.0 44.2 3.2 7.2 13.3 3.2 1 1 2 3 3 3 0 Ezrin/radixin/moesin family IncA PF04156.9 KFM04609.1 - 5.1 6.6 46.5 1.5 8.3 5.1 3.6 1 1 3 4 4 4 0 IncA protein WXG100 PF06013.7 KFM04609.1 - 5.2 7.1 15.4 8.7 6.4 0.0 3.8 2 2 1 3 3 3 0 Proteins of 100 residues with WXG HGTP_anticodon PF03129.15 KFM04609.1 - 6.9 6.6 9.1 0.91 9.5 0.1 3.6 4 0 0 4 4 4 0 Anticodon binding domain DUF4200 PF13863.1 KFM04609.1 - 8.7 6.3 45.3 0.2 11.5 4.7 5.1 1 1 4 5 5 5 0 Domain of unknown function (DUF4200) Peptidase_M18 PF02127.10 KFM04610.1 - 1e-161 538.2 0.0 1.2e-161 538.0 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 KFM04610.1 - 9.4e-08 31.1 0.0 1.2e-05 24.2 0.0 2.5 3 0 0 3 3 3 2 M42 glutamyl aminopeptidase Y_phosphatase PF00102.22 KFM04611.1 - 1.5e-72 243.7 0.0 2e-72 243.3 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFM04611.1 - 0.0077 15.8 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFM04611.1 - 0.024 14.8 0.0 0.3 11.3 0.0 2.5 2 0 0 2 2 2 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KFM04611.1 - 0.036 14.1 0.1 0.51 10.3 0.0 2.3 2 0 0 2 2 2 0 Inositol hexakisphosphate DnaJ PF00226.26 KFM04612.1 - 3.4e-28 97.1 4.6 4.8e-28 96.6 3.2 1.2 1 0 0 1 1 1 1 DnaJ domain YqgF PF14639.1 KFM04612.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 Tubulin PF00091.20 KFM04613.1 - 1.8e-63 214.2 0.0 2.4e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFM04613.1 - 1.3e-51 173.8 0.0 2.7e-51 172.8 0.0 1.5 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KFM04613.1 - 0.0011 18.5 0.0 0.0019 17.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain DUF4253 PF14062.1 KFM04613.1 - 0.055 13.1 0.0 1.4 8.5 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4253) Toxin_4 PF00706.12 KFM04614.1 - 0.091 12.9 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Anenome neurotoxin Tubulin PF00091.20 KFM04615.1 - 3.9e-69 232.7 0.0 5.1e-69 232.3 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFM04615.1 - 2.9e-51 172.7 0.0 4.9e-51 172.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KFM04615.1 - 0.00095 18.6 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain DUF4253 PF14062.1 KFM04615.1 - 0.054 13.1 0.0 1.4 8.6 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4253) Pkinase PF00069.20 KFM04617.1 - 6.2e-43 146.8 0.0 7.2e-43 146.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM04617.1 - 5.9e-27 94.3 0.0 7.2e-27 94.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM04617.1 - 0.00017 20.6 0.0 0.00021 20.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFM04617.1 - 0.00045 20.0 0.6 0.022 14.5 0.4 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KFM04617.1 - 0.0092 15.0 0.1 0.013 14.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APG9 PF04109.11 KFM04618.1 - 3.9e-135 450.5 1.2 5.3e-135 450.0 0.8 1.2 1 0 0 1 1 1 1 Autophagy protein Apg9 EMP24_GP25L PF01105.19 KFM04618.1 - 0.068 12.8 0.1 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD ABC_tran PF00005.22 KFM04619.1 - 6.8e-34 117.1 0.0 1.2e-33 116.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KFM04619.1 - 5.7e-29 101.3 11.5 8.7e-29 100.7 7.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 KFM04619.1 - 4.1e-06 26.1 0.1 0.00027 20.2 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KFM04619.1 - 8.1e-05 22.7 0.1 0.0033 17.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFM04619.1 - 0.00022 21.2 0.2 0.00051 20.0 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFM04619.1 - 0.00083 19.5 0.1 0.0073 16.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KFM04619.1 - 0.002 17.3 0.0 0.0039 16.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KFM04619.1 - 0.0021 17.5 0.0 0.0049 16.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.24 KFM04619.1 - 0.0064 16.6 0.1 0.1 12.7 0.0 2.4 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 KFM04619.1 - 0.0065 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain AAA_17 PF13207.1 KFM04619.1 - 0.0093 16.7 0.0 0.02 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 KFM04619.1 - 0.015 15.1 0.3 0.17 11.7 0.2 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 KFM04619.1 - 0.017 15.0 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KFM04619.1 - 0.022 13.8 0.0 0.043 12.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Acyl-CoA_dh_1 PF00441.19 KFM04619.1 - 0.067 13.3 0.1 0.22 11.6 0.0 1.8 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain DUF4530 PF15039.1 KFM04619.1 - 0.08 12.8 0.1 9.2 6.2 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4530) Maf PF02545.9 KFM04619.1 - 0.11 11.5 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Maf-like protein AAA_5 PF07728.9 KFM04619.1 - 0.15 11.7 0.2 2.2 8.0 0.0 2.5 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) MobB PF03205.9 KFM04619.1 - 0.16 11.7 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B zf-AN1 PF01428.11 KFM04620.1 - 5.6e-21 74.1 24.8 8.2e-13 47.9 6.1 2.9 4 0 0 4 4 4 2 AN1-like Zinc finger Transp_Tc5_C PF04236.10 KFM04620.1 - 0.042 14.0 16.4 0.46 10.7 1.4 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain zf-C3HC PF07967.8 KFM04620.1 - 0.25 11.1 7.5 2.1 8.1 1.0 2.2 2 0 0 2 2 2 0 C3HC zinc finger-like zinc_ribbon_4 PF13717.1 KFM04620.1 - 0.53 10.0 11.5 0.69 9.6 1.3 3.4 3 0 0 3 3 3 0 zinc-ribbon domain IBR PF01485.16 KFM04620.1 - 1.2 9.0 24.3 17 5.3 2.3 3.4 1 1 1 2 2 2 0 IBR domain zinc_ribbon_5 PF13719.1 KFM04620.1 - 1.5 8.4 11.8 0.99 9.0 1.2 3.4 3 0 0 3 3 3 0 zinc-ribbon domain Reticulon PF02453.12 KFM04621.1 - 0.0004 20.0 0.1 0.00067 19.2 0.0 1.3 1 0 0 1 1 1 1 Reticulon Abi PF02517.11 KFM04621.1 - 0.11 12.6 0.7 0.24 11.5 0.5 1.5 1 0 0 1 1 1 0 CAAX protease self-immunity Cyclin PF08613.6 KFM04622.1 - 6.4e-11 42.8 0.0 8e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KFM04622.1 - 9.9e-06 25.1 0.1 1.4e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Xan_ur_permease PF00860.15 KFM04623.1 - 5.4e-64 216.0 19.9 8.6e-64 215.4 13.8 1.3 1 0 0 1 1 1 1 Permease family XLF PF09302.6 KFM04624.1 - 5.9e-39 133.5 0.0 8.4e-39 133.0 0.0 1.2 1 0 0 1 1 1 1 XLF (XRCC4-like factor) Hint PF01079.15 KFM04625.1 - 7.6e-72 241.0 0.0 9.4e-72 240.7 0.0 1.1 1 0 0 1 1 1 1 Hint module HH_signal PF01085.13 KFM04625.1 - 4.1e-55 185.7 0.6 5.6e-55 185.2 0.4 1.2 1 0 0 1 1 1 1 Hedgehog amino-terminal signalling domain Peptidase_M15_3 PF08291.6 KFM04625.1 - 0.00098 18.9 0.1 0.0015 18.3 0.1 1.2 1 0 0 1 1 1 1 Peptidase M15 Homeobox PF00046.24 KFM04626.1 - 1.2e-22 79.3 7.1 1.7e-22 78.7 4.9 1.3 1 0 0 1 1 1 1 Homeobox domain QLQ PF08880.6 KFM04626.1 - 0.0028 17.0 0.2 0.005 16.2 0.2 1.4 1 0 0 1 1 1 1 QLQ Motile_Sperm PF00635.21 KFM04627.1 - 7.4e-18 64.1 0.0 0.15 11.7 0.0 9.1 10 0 0 10 10 10 6 MSP (Major sperm protein) domain PapD-like PF14874.1 KFM04627.1 - 1.4e-05 24.9 3.1 0.66 9.9 0.0 6.0 7 0 0 7 7 7 1 Flagellar-associated PapD-like Ets PF00178.17 KFM04628.1 - 5.3e-40 135.4 0.9 7.2e-40 135.0 0.6 1.2 1 0 0 1 1 1 1 Ets-domain wnt PF00110.14 KFM04629.1 - 1.7e-121 405.2 18.9 1.9e-121 405.0 13.1 1.0 1 0 0 1 1 1 1 wnt family p450 PF00067.17 KFM04630.1 - 2.5e-101 339.4 0.0 3.1e-101 339.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CBS PF00571.23 KFM04631.1 - 1.4e-41 140.0 2.8 2e-12 46.6 0.1 4.2 4 0 0 4 4 4 4 CBS domain TTL PF03133.10 KFM04632.1 - 8.3e-101 336.7 0.1 1.3e-100 336.1 0.1 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 KFM04632.1 - 2.3e-05 23.3 0.3 0.00053 18.8 0.0 2.8 2 1 1 3 3 3 1 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 KFM04632.1 - 0.029 14.1 0.0 0.074 12.7 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_Ter PF15632.1 KFM04632.1 - 0.06 12.0 0.0 6.3 5.4 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 KFM04632.1 - 0.093 12.5 0.0 6.5 6.6 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp domain zf-RING_2 PF13639.1 KFM04633.1 - 1.2e-13 50.6 4.6 2.3e-13 49.7 3.2 1.5 1 0 0 1 1 1 1 Ring finger domain RWD PF05773.17 KFM04633.1 - 2.9e-06 27.1 0.0 6.1e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 RWD domain zf-RING_5 PF14634.1 KFM04633.1 - 8.8e-05 22.1 7.1 0.00023 20.8 4.9 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFM04633.1 - 0.00067 19.6 4.3 0.0028 17.6 2.5 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM04633.1 - 0.0053 16.3 5.1 0.065 12.9 3.8 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM04633.1 - 0.013 15.1 3.4 0.035 13.7 2.4 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFM04633.1 - 0.071 13.2 9.3 0.2 11.8 4.4 2.7 2 1 1 3 3 3 0 RING-H2 zinc finger zf-Apc11 PF12861.2 KFM04633.1 - 0.14 11.9 5.0 2.1 8.2 3.5 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger BCS1_N PF08740.6 KFM04634.1 - 2.1e-50 170.9 3.0 4.5e-50 169.8 2.1 1.6 1 1 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 KFM04634.1 - 1.6e-20 73.6 0.0 2.5e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KFM04634.1 - 0.00014 21.9 0.0 0.0024 18.0 0.0 2.5 2 1 0 2 2 2 1 RNA helicase AAA_17 PF13207.1 KFM04634.1 - 0.00023 21.9 0.0 0.00085 20.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFM04634.1 - 0.0026 17.7 0.1 0.007 16.3 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 KFM04634.1 - 0.0034 16.3 0.0 0.006 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 KFM04634.1 - 0.0066 16.3 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KFM04634.1 - 0.0083 15.5 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KFM04634.1 - 0.0085 16.3 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_5 PF07728.9 KFM04634.1 - 0.013 15.2 0.0 0.029 14.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KFM04634.1 - 0.014 15.5 0.0 0.099 12.7 0.0 2.3 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.1 KFM04634.1 - 0.025 14.3 0.0 0.082 12.6 0.0 1.9 2 0 0 2 2 1 0 Part of AAA domain Rad17 PF03215.10 KFM04634.1 - 0.04 12.6 0.0 0.066 11.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 KFM04634.1 - 0.042 13.7 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KFM04634.1 - 0.052 13.0 0.0 0.2 11.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain IstB_IS21 PF01695.12 KFM04634.1 - 0.058 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Arch_ATPase PF01637.13 KFM04634.1 - 0.064 12.9 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase Polyoma_lg_T_C PF06431.6 KFM04634.1 - 0.087 11.4 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus AAA_28 PF13521.1 KFM04634.1 - 0.089 12.7 0.0 0.4 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 KFM04634.1 - 0.097 12.6 0.0 0.19 11.6 0.0 1.5 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.7 KFM04634.1 - 0.16 11.0 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_11 PF13086.1 KFM04634.1 - 0.18 11.3 0.0 0.38 10.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KFM04634.1 - 0.2 11.2 0.1 0.4 10.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain zf-H2C2_2 PF13465.1 KFM04635.1 - 7.3e-44 145.9 328.8 1.1e-05 25.4 1.5 38.0 37 2 1 38 38 38 24 Zinc-finger double domain zf-C2H2 PF00096.21 KFM04635.1 - 2.9e-23 80.7 382.1 0.00015 21.8 1.0 39.4 40 0 0 40 40 40 24 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 KFM04635.1 - 6.2e-22 76.4 348.7 0.011 15.9 0.3 37.5 40 0 0 40 40 40 24 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 KFM04635.1 - 1.2e-08 34.6 366.1 0.0027 17.8 0.4 39.4 40 0 0 40 40 40 24 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM04635.1 - 0.0033 17.2 5.6 0.0033 17.2 3.9 19.1 25 1 0 25 25 25 4 C2H2-type zinc finger PI-PLC-X PF00388.14 KFM04636.1 - 4.2e-63 211.1 0.0 6.5e-63 210.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KFM04636.1 - 8.7e-47 157.9 0.0 1.5e-46 157.2 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 KFM04636.1 - 7e-25 86.8 1.2 3.2e-24 84.7 0.0 2.4 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_10 PF14788.1 KFM04636.1 - 4.2e-22 77.5 0.6 4.2e-22 77.5 0.4 2.5 2 1 1 3 3 3 1 EF hand C2 PF00168.25 KFM04636.1 - 3.3e-16 58.8 0.0 6.7e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 C2 domain EF-hand_1 PF00036.27 KFM04636.1 - 1.3e-09 36.6 0.1 0.00012 21.1 0.1 3.0 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KFM04636.1 - 2.2e-08 33.3 3.0 0.0097 15.7 0.0 3.9 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.1 KFM04636.1 - 4e-07 30.0 3.1 0.0044 17.1 0.5 2.9 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KFM04636.1 - 1.1e-06 27.7 0.3 0.0067 15.7 0.1 3.0 2 0 0 2 2 2 2 EF hand Rcd1 PF04078.8 KFM04637.1 - 1.1e-138 460.3 0.4 1.3e-138 460.1 0.3 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like OmdA PF13376.1 KFM04637.1 - 0.18 11.4 0.4 3.6 7.2 0.0 2.7 3 1 0 3 3 3 0 Bacteriocin-protection, YdeI or OmpD-Associated UCH PF00443.24 KFM04638.1 - 9.6e-63 211.7 15.8 1.6e-62 211.0 11.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFM04638.1 - 2e-20 73.4 14.3 5.1e-18 65.5 9.9 2.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UIM PF02809.15 KFM04638.1 - 3.3e-07 29.2 22.5 0.0012 18.1 0.2 4.0 3 0 0 3 3 3 3 Ubiquitin interaction motif Elongin_A PF06881.6 KFM04638.1 - 0.14 12.5 6.3 0.56 10.6 4.4 2.0 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Gelsolin PF00626.17 KFM04639.1 - 3e-109 356.8 0.1 4.7e-20 71.0 0.0 6.3 6 0 0 6 6 6 6 Gelsolin repeat VHP PF02209.14 KFM04639.1 - 9e-14 50.8 2.1 2e-13 49.7 1.5 1.6 1 0 0 1 1 1 1 Villin headpiece domain DUF2786 PF10979.3 KFM04639.1 - 1.4 8.7 4.6 2.3 8.0 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2786) NIF PF03031.13 KFM04640.1 - 6e-40 136.5 0.0 7.2e-40 136.2 0.0 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Sulfotransfer_3 PF13469.1 KFM04640.1 - 0.1 13.5 0.5 0.12 13.3 0.3 1.1 1 0 0 1 1 1 0 Sulfotransferase family Nramp PF01566.13 KFM04641.1 - 3e-115 384.8 11.3 5e-115 384.0 7.8 1.4 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Lactamase_B PF00753.22 KFM04643.1 - 1.1e-10 41.5 0.2 2.5e-06 27.2 0.0 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily WD40 PF00400.27 KFM04644.1 - 2.1e-37 125.6 12.1 2.7e-06 27.0 0.2 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 KFM04644.1 - 2.7e-07 30.4 0.2 0.018 14.7 0.1 3.5 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KFM04644.1 - 4.7e-05 21.7 0.1 0.14 10.2 0.0 2.5 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KFM04644.1 - 0.0012 17.7 0.0 0.039 12.6 0.0 2.5 2 1 1 3 3 3 1 Nup133 N terminal like PQQ PF01011.16 KFM04644.1 - 0.053 13.0 2.8 9.3 5.9 0.0 4.1 4 0 0 4 4 4 0 PQQ enzyme repeat Apc4_WD40 PF12894.2 KFM04644.1 - 0.074 12.5 0.0 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain P34-Arc PF04045.9 KFM04645.1 - 5.8e-104 346.6 1.8 6.9e-104 346.3 1.3 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.7 KFM04645.1 - 0.0063 15.9 0.1 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) RUN PF02759.14 KFM04646.1 - 3.5e-11 42.9 0.2 4e-11 42.8 0.1 1.0 1 0 0 1 1 1 1 RUN domain PTB PF08416.8 KFM04647.1 - 7.4e-43 145.5 0.0 1.4e-42 144.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PTEN_C2 PF10409.4 KFM04647.1 - 3.7e-31 107.6 0.0 5.9e-31 106.9 0.0 1.3 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein SH2 PF00017.19 KFM04647.1 - 9e-09 35.0 0.0 2.3e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 SH2 domain Yae1_N PF09811.4 KFM04648.1 - 3.9e-13 48.6 33.4 7.6 6.1 23.1 3.4 1 1 0 1 1 1 1 Essential protein Yae1, N terminal Thyroglobulin_1 PF00086.13 KFM04650.1 - 8.8e-22 76.2 3.6 8.8e-22 76.2 2.5 1.6 2 0 0 2 2 2 1 Thyroglobulin type-1 repeat Ribosomal_L37ae PF01780.14 KFM04651.1 - 1.7e-39 133.5 9.5 1.9e-39 133.4 6.6 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-C4_ClpX PF06689.8 KFM04651.1 - 0.018 14.5 0.3 0.018 14.5 0.2 1.6 2 0 0 2 2 2 0 ClpX C4-type zinc finger Rsm1 PF08600.5 KFM04651.1 - 0.02 14.7 0.6 0.028 14.2 0.4 1.3 1 0 0 1 1 1 0 Rsm1-like zf-DHHC PF01529.15 KFM04651.1 - 0.024 14.0 0.1 0.029 13.7 0.1 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase Elf1 PF05129.8 KFM04651.1 - 0.027 14.1 0.3 0.038 13.6 0.2 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like OrfB_Zn_ribbon PF07282.6 KFM04651.1 - 0.032 13.8 0.8 0.045 13.4 0.6 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain A2L_zn_ribbon PF08792.5 KFM04651.1 - 0.055 12.9 2.7 0.088 12.2 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 KFM04651.1 - 0.067 13.0 1.8 0.1 12.3 1.2 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 KFM04651.1 - 0.21 11.5 1.3 0.33 10.9 0.1 1.9 2 0 0 2 2 2 0 Zinc ribbon domain Rep_fac-A_C PF08646.5 KFM04651.1 - 0.22 11.2 2.3 0.32 10.6 1.6 1.4 1 1 0 1 1 1 0 Replication factor-A C terminal domain zf-BED PF02892.10 KFM04651.1 - 0.39 10.5 5.7 1.6 8.5 0.4 2.3 1 1 1 2 2 2 0 BED zinc finger CarbpepA_inh PF02977.10 KFM04651.1 - 2.4 7.7 6.1 0.65 9.6 1.0 2.0 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor RINGv PF12906.2 KFM04652.1 - 3e-10 39.9 14.8 5.9e-10 39.0 10.3 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 KFM04652.1 - 1.4 8.8 12.6 2.8 7.8 8.7 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.20 KFM04652.1 - 2 8.1 8.3 8.1 6.2 5.8 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ku_N PF03731.10 KFM04654.1 - 1.7e-62 210.7 3.3 2e-62 210.5 0.5 2.2 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.11 KFM04654.1 - 5.6e-45 153.2 1.5 9.5e-45 152.4 1.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.6 KFM04654.1 - 1.8e-42 144.0 4.4 4.9e-41 139.3 1.3 2.8 2 0 0 2 2 2 1 Ku C terminal domain like Ku_C PF03730.9 KFM04654.1 - 2.5e-26 92.0 4.6 4.6e-26 91.1 1.9 2.5 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm VWA_2 PF13519.1 KFM04654.1 - 1.8e-06 28.1 0.0 3.8e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KFM04654.1 - 0.00046 19.9 0.2 0.0011 18.7 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain adh_short_C2 PF13561.1 KFM04655.1 - 6.5e-27 94.8 0.1 7.4e-27 94.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFM04655.1 - 1.8e-19 70.2 0.1 2.2e-19 69.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFM04655.1 - 0.00037 20.2 0.0 0.0006 19.5 0.0 1.4 1 1 0 1 1 1 1 KR domain CABS1 PF15367.1 KFM04655.1 - 0.051 12.4 0.0 0.071 11.9 0.0 1.1 1 0 0 1 1 1 0 Calcium-binding and spermatid-specific protein 1 Pkinase PF00069.20 KFM04656.1 - 5.6e-65 219.0 0.0 7.2e-65 218.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM04656.1 - 4.6e-40 137.3 0.0 6.9e-40 136.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PB1 PF00564.19 KFM04656.1 - 5.1e-13 48.4 0.2 1.1e-12 47.4 0.2 1.5 1 0 0 1 1 1 1 PB1 domain Kinase-like PF14531.1 KFM04656.1 - 5.4e-05 22.2 0.0 0.0017 17.4 0.0 2.2 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFM04656.1 - 0.036 13.1 0.0 0.06 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KFM04656.1 - 0.047 12.5 0.0 1.1 7.9 0.0 2.1 2 0 0 2 2 2 0 Seadornavirus VP7 Helicase_C_3 PF13625.1 KFM04657.1 - 1.6e-31 108.7 0.0 7.8e-31 106.5 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFM04657.1 - 6.8e-15 55.3 0.0 2.8e-14 53.3 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KFM04657.1 - 4.8e-10 39.1 0.0 1.2e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFM04657.1 - 2.1e-06 27.3 0.0 4.7e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.18 KFM04657.1 - 9.1e-06 24.6 0.0 1.6e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF3890 PF13029.1 KFM04657.1 - 0.066 13.2 0.3 0.19 11.7 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3890) AAA_22 PF13401.1 KFM04657.1 - 0.09 12.9 0.0 0.39 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain TUSC2 PF15000.1 KFM04657.1 - 0.098 12.7 0.5 0.57 10.2 0.1 2.4 2 0 0 2 2 2 0 Tumour suppressor candidate 2 p450 PF00067.17 KFM04658.1 - 1.7e-100 336.7 0.0 1.8e-100 336.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BAR PF03114.13 KFM04660.1 - 1.3e-49 168.7 9.7 1.7e-49 168.3 6.7 1.1 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 KFM04660.1 - 1.9e-11 43.3 0.1 7.4e-11 41.4 0.1 2.0 1 1 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM04660.1 - 3.3e-07 29.6 0.2 8.6e-07 28.2 0.1 1.8 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFM04660.1 - 2.2e-06 27.0 0.0 5.2e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain IFT57 PF10498.4 KFM04660.1 - 0.016 13.9 3.9 0.41 9.3 0.3 2.3 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 IR1-M PF12185.3 KFM04660.1 - 0.075 12.7 1.3 3.9 7.2 0.2 3.5 3 0 0 3 3 3 0 Nup358/RanBP2 E3 ligase domain FliS PF02561.9 KFM04660.1 - 0.16 11.7 2.1 0.2 11.5 0.1 2.0 2 0 0 2 2 2 0 Flagellar protein FliS V-SNARE PF05008.10 KFM04660.1 - 0.25 11.5 3.5 1.1 9.4 0.1 2.8 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus ThylakoidFormat PF11264.3 KFM04660.1 - 0.55 9.8 4.8 0.32 10.5 0.8 2.0 2 0 0 2 2 2 0 Thylakoid formation protein Arfaptin PF06456.8 KFM04660.1 - 0.91 8.8 7.7 2.2 7.5 5.4 1.7 1 1 0 1 1 1 0 Arfaptin-like domain Protocadherin PF08374.6 KFM04661.1 - 0.0021 17.7 0.0 0.0021 17.7 0.0 1.1 1 0 0 1 1 1 1 Protocadherin Shisa PF13908.1 KFM04661.1 - 0.0024 18.0 0.0 0.0024 18.0 0.0 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Spore_SspJ PF09575.5 KFM04661.1 - 0.0033 17.5 0.3 0.0043 17.2 0.2 1.2 1 0 0 1 1 1 1 Small spore protein J (Spore_SspJ) Syndecan PF01034.15 KFM04661.1 - 0.0049 16.4 0.1 0.0065 16.1 0.1 1.2 1 0 0 1 1 1 1 Syndecan domain EphA2_TM PF14575.1 KFM04661.1 - 0.0058 17.0 0.0 0.0068 16.7 0.0 1.2 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain LRR19-TM PF15176.1 KFM04661.1 - 0.024 14.3 0.0 0.025 14.2 0.0 1.1 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Trp_oprn_chp PF09534.5 KFM04661.1 - 0.061 12.9 0.0 0.072 12.6 0.0 1.0 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Baculo_11_kDa PF06143.6 KFM04661.1 - 0.072 12.4 0.0 0.09 12.1 0.0 1.2 1 0 0 1 1 1 0 Baculovirus 11 kDa family OAD_gamma PF04277.8 KFM04661.1 - 0.083 13.2 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Chordopox_A13L PF05961.6 KFM04661.1 - 0.1 12.5 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus A13L protein ODV-E18 PF10717.4 KFM04661.1 - 0.12 11.8 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 OppC_N PF12911.2 KFM04661.1 - 0.12 11.7 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Herpes_gE PF02480.11 KFM04661.1 - 0.12 10.5 0.0 0.12 10.5 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Adeno_E3_CR2 PF02439.10 KFM04661.1 - 0.46 10.0 6.4 0.73 9.4 4.5 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF2970 PF11174.3 KFM04661.1 - 5.6 6.6 7.5 8.3 6.0 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) Laminin_G_2 PF02210.19 KFM04662.1 - 4.3e-62 207.8 1.0 7.9e-22 77.6 0.0 3.2 3 0 0 3 3 3 3 Laminin G domain Laminin_G_1 PF00054.18 KFM04662.1 - 1.2e-46 157.9 0.1 3.1e-18 66.0 0.0 3.3 3 0 0 3 3 3 3 Laminin G domain Laminin_G_3 PF13385.1 KFM04662.1 - 9.8e-10 38.8 0.1 0.0025 18.0 0.0 3.8 4 0 0 4 4 4 2 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.22 KFM04662.1 - 2.5e-06 27.3 30.8 3.5e-05 23.6 3.7 4.0 3 1 0 3 3 3 2 EGF-like domain COLFI PF01410.13 KFM04662.1 - 0.00088 18.7 0.1 0.032 13.6 0.1 2.5 2 0 0 2 2 2 1 Fibrillar collagen C-terminal domain EGF_2 PF07974.8 KFM04662.1 - 0.0053 16.8 12.2 0.0053 16.8 8.5 3.9 4 0 0 4 4 4 2 EGF-like domain F5_F8_type_C PF00754.20 KFM04663.1 - 1.7e-15 56.9 1.7 1.9e-15 56.8 1.2 1.0 1 0 0 1 1 1 1 F5/8 type C domain Ras PF00071.17 KFM04665.1 - 3.6e-53 179.2 0.0 4.1e-53 179.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM04665.1 - 9.1e-22 77.7 0.0 1.3e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KFM04665.1 - 1e-07 31.6 0.1 3.2e-07 29.9 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.16 KFM04665.1 - 1.2e-06 27.9 0.0 1.4e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFM04665.1 - 1.3e-05 25.1 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KFM04665.1 - 0.015 14.8 0.6 0.073 12.6 0.0 1.9 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.7 KFM04665.1 - 0.038 13.1 0.0 0.043 12.9 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 KFM04665.1 - 0.077 12.9 0.0 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.1 KFM04665.1 - 0.12 11.9 0.1 0.2 11.1 0.0 1.3 1 1 0 1 1 1 0 AAA domain Y_phosphatase PF00102.22 KFM04667.1 - 8.5e-80 267.4 0.6 1.3e-79 266.8 0.4 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase FERM_C PF09380.5 KFM04667.1 - 1.6e-24 85.9 0.4 3.6e-24 84.7 0.3 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.13 KFM04667.1 - 7.3e-24 84.3 1.7 8.3e-24 84.1 0.3 1.8 2 0 0 2 2 2 1 FERM central domain FERM_N PF09379.5 KFM04667.1 - 2.6e-21 75.4 0.0 1.4e-20 73.1 0.0 2.1 2 0 0 2 2 2 1 FERM N-terminal domain PDZ PF00595.19 KFM04667.1 - 1.6e-19 69.8 0.0 4.5e-19 68.3 0.0 1.8 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) FA PF08736.6 KFM04667.1 - 3.2e-15 55.6 2.6 4.6e-15 55.1 0.4 2.2 2 0 0 2 2 2 1 FERM adjacent (FA) PTPlike_phytase PF14566.1 KFM04667.1 - 6.1e-05 23.1 0.0 0.00015 21.8 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.15 KFM04667.1 - 0.0002 20.9 0.0 0.00046 19.7 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFM04667.1 - 0.0029 17.8 0.0 0.0081 16.4 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family FERM_C PF09380.5 KFM04668.1 - 9.8e-21 73.7 0.0 2e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.13 KFM04668.1 - 1.7e-19 70.2 0.1 4e-19 69.0 0.1 1.7 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.5 KFM04668.1 - 5.2e-19 68.0 0.9 2.3e-18 66.0 0.0 2.5 3 0 0 3 3 3 1 FERM N-terminal domain FA PF08736.6 KFM04668.1 - 2.1e-14 53.0 11.3 4.8e-14 51.8 7.9 1.6 1 0 0 1 1 1 1 FERM adjacent (FA) Ras PF00071.17 KFM04669.1 - 1.6e-51 173.8 0.2 1.8e-51 173.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM04669.1 - 7.6e-18 65.1 0.0 1e-17 64.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM04669.1 - 3.6e-10 39.3 0.0 4.2e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KFM04669.1 - 1.4e-05 24.4 0.0 1.9e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 KFM04669.1 - 2.4e-05 23.8 0.0 7.5e-05 22.2 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFM04669.1 - 0.00054 19.9 0.0 0.00065 19.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFM04669.1 - 0.0014 17.8 0.0 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Septin PF00735.13 KFM04669.1 - 0.007 15.4 0.0 1.1 8.1 0.0 2.1 2 0 0 2 2 2 2 Septin AAA_25 PF13481.1 KFM04669.1 - 0.0082 15.5 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 KFM04669.1 - 0.012 14.8 0.1 0.08 12.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 FeoB_N PF02421.13 KFM04669.1 - 0.02 14.1 0.0 0.28 10.4 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B IMP_cyclohyd PF07826.6 KFM04669.1 - 0.068 12.5 0.1 0.085 12.1 0.0 1.2 1 0 0 1 1 1 0 IMP cyclohydrolase-like protein zf-C2H2 PF00096.21 KFM04670.1 - 2.9e-18 65.0 31.9 0.00063 19.9 0.3 6.4 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM04670.1 - 8.1e-16 57.4 30.2 3.2e-07 30.3 1.0 5.7 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM04670.1 - 2.7e-07 30.4 32.3 0.022 15.0 0.1 6.1 6 0 0 6 6 6 4 C2H2-type zinc finger CP2 PF04516.10 KFM04671.1 - 6.5e-72 241.3 0.1 9.3e-72 240.8 0.0 1.1 1 0 0 1 1 1 1 CP2 transcription factor SAM_PNT PF02198.11 KFM04671.1 - 0.019 14.7 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain CLASP_N PF12348.3 KFM04672.1 - 4.8e-59 199.4 15.6 2e-39 135.2 0.4 4.7 4 1 1 5 5 5 3 CLASP N terminal HEAT PF02985.17 KFM04672.1 - 5.1e-20 69.7 10.0 9e-06 25.3 0.0 10.7 11 0 0 11 11 11 3 HEAT repeat HEAT_2 PF13646.1 KFM04672.1 - 1.3e-13 50.9 6.2 0.0052 17.0 0.2 8.0 6 2 2 8 8 8 2 HEAT repeats HEAT_EZ PF13513.1 KFM04672.1 - 6.1e-11 42.4 4.5 0.058 13.9 0.0 6.7 6 0 0 6 6 5 2 HEAT-like repeat Sec7_N PF12783.2 KFM04672.1 - 1.3e-07 31.2 5.0 0.0033 16.8 0.0 4.9 4 0 0 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Vac14_Fab1_bd PF12755.2 KFM04672.1 - 1.6e-07 31.6 1.6 1.5 9.2 0.0 5.9 6 0 0 6 6 6 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 KFM04672.1 - 1.2e-05 25.2 6.1 0.0032 17.3 0.2 4.9 4 2 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 KFM04672.1 - 1.4e-05 23.6 8.6 1.1 7.5 0.0 5.9 5 2 2 8 8 8 3 Adaptin N terminal region DUF2435 PF10363.4 KFM04672.1 - 3.1e-05 23.7 2.1 0.43 10.5 0.0 4.3 3 1 0 3 3 3 2 Protein of unknown function (DUF2435) Ipi1_N PF12333.3 KFM04672.1 - 3.2e-05 23.8 3.6 0.16 11.9 0.1 5.5 5 0 0 5 5 5 1 Rix1 complex component involved in 60S ribosome maturation TAN PF11640.3 KFM04672.1 - 0.00023 20.9 4.2 0.037 13.7 0.0 3.8 3 0 0 3 3 3 1 Telomere-length maintenance and DNA damage repair ParcG PF10274.4 KFM04672.1 - 0.00029 20.7 1.6 0.0062 16.4 0.1 3.4 2 1 1 3 3 3 1 Parkin co-regulated protein DUF2454 PF10521.4 KFM04672.1 - 0.013 14.5 4.7 1.3 7.9 0.0 4.2 4 2 1 5 5 5 0 Protein of unknown function (DUF2454) Nipped-B_C PF12830.2 KFM04672.1 - 0.06 12.9 2.6 9.9 5.7 0.0 4.1 4 0 0 4 4 4 0 Sister chromatid cohesion C-terminus TPR_20 PF14561.1 KFM04672.1 - 0.066 13.3 3.0 0.32 11.1 0.3 3.4 2 1 1 3 3 2 0 Tetratricopeptide repeat hNIFK_binding PF12196.3 KFM04673.1 - 2.3e-15 55.6 2.5 4.2e-15 54.8 1.7 1.5 1 0 0 1 1 1 1 FHA Ki67 binding domain of hNIFK RRM_1 PF00076.17 KFM04673.1 - 4.7e-06 26.1 0.0 8.4e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM04673.1 - 0.0054 16.5 0.0 0.0095 15.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM04673.1 - 0.0066 16.3 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Olfactory_mark PF06554.7 KFM04673.1 - 0.11 12.0 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Olfactory marker protein Translin PF01997.11 KFM04674.1 - 8.8e-49 165.8 0.1 1e-48 165.5 0.1 1.0 1 0 0 1 1 1 1 Translin family RhoGEF PF00621.15 KFM04675.1 - 1.1e-41 142.6 2.8 2.3e-41 141.6 1.9 1.5 1 0 0 1 1 1 1 RhoGEF domain IQ PF00612.22 KFM04677.1 - 6.2e-12 44.0 25.0 8.3e-07 28.1 0.5 5.4 5 0 0 5 5 5 4 IQ calmodulin-binding motif EAF PF09816.4 KFM04678.1 - 8.5e-19 67.5 0.5 3.1e-18 65.7 0.0 2.1 2 1 0 2 2 2 1 RNA polymerase II transcription elongation factor Nha1_C PF08619.5 KFM04678.1 - 0.00029 20.2 10.4 0.00035 19.9 7.2 1.1 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus DUF605 PF04652.11 KFM04678.1 - 0.066 12.6 16.4 0.072 12.4 11.4 1.1 1 0 0 1 1 1 0 Vta1 like PAN_3 PF08277.7 KFM04678.1 - 0.07 12.7 0.1 0.07 12.7 0.0 1.8 2 0 0 2 2 2 0 PAN-like domain Cwf_Cwc_15 PF04889.7 KFM04678.1 - 0.38 10.4 13.4 0.62 9.7 9.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_viral_N PF00242.12 KFM04678.1 - 1.1 8.2 9.4 1.3 8.0 6.5 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain PTR2 PF00854.16 KFM04679.1 - 1.3e-51 175.5 4.5 1.7e-51 175.1 3.1 1.1 1 0 0 1 1 1 1 POT family Cupin_8 PF13621.1 KFM04680.1 - 1.2e-36 126.5 0.0 1.6e-36 126.0 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KFM04680.1 - 2.5e-08 33.5 0.0 4e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.17 KFM04680.1 - 0.00086 19.5 0.0 0.0018 18.5 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Pox_C7_F8A PF03287.9 KFM04680.1 - 0.082 12.6 0.0 2.3 7.8 0.0 2.3 2 0 0 2 2 2 0 Poxvirus C7/F8A protein MFS_1 PF07690.11 KFM04681.1 - 2.5e-06 26.4 29.5 2.5e-06 26.4 20.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily AceK PF06315.6 KFM04681.1 - 0.26 9.5 0.0 0.35 9.1 0.0 1.1 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) Sema PF01403.14 KFM04682.1 - 6.6e-137 456.5 0.3 2e-136 455.0 0.1 1.8 1 1 1 2 2 2 1 Sema domain TSP_1 PF00090.14 KFM04682.1 - 8.5e-39 131.4 93.8 1.8e-10 40.7 6.0 7.5 7 0 0 7 7 7 5 Thrombospondin type 1 domain 7TM_GPCR_Srz PF10325.4 KFM04682.1 - 0.079 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srz Thioredoxin PF00085.15 KFM04683.1 - 2.2e-74 245.7 0.9 1.6e-25 88.7 0.0 4.2 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_2 PF13098.1 KFM04683.1 - 6.6e-29 100.3 6.4 7.5e-09 35.7 0.1 4.9 4 2 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KFM04683.1 - 5.6e-20 71.1 0.2 2e-05 24.5 0.0 3.6 3 0 0 3 3 3 3 Thioredoxin-like Thioredoxin_8 PF13905.1 KFM04683.1 - 7.4e-18 64.4 1.6 4.7e-05 23.4 0.1 5.4 3 2 2 5 5 5 3 Thioredoxin-like AhpC-TSA PF00578.16 KFM04683.1 - 2.9e-16 59.2 0.8 4.7e-05 23.0 0.0 3.6 4 0 0 4 4 4 3 AhpC/TSA family Redoxin PF08534.5 KFM04683.1 - 1.5e-13 50.5 0.5 0.0039 16.7 0.0 3.4 3 0 0 3 3 3 3 Redoxin Thioredoxin_6 PF13848.1 KFM04683.1 - 2.2e-11 43.9 3.2 0.0024 17.6 0.0 4.8 5 0 0 5 5 5 3 Thioredoxin-like domain Thioredoxin_9 PF14595.1 KFM04683.1 - 9.8e-09 34.8 0.3 0.056 12.9 0.0 3.5 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_3 PF13192.1 KFM04683.1 - 8.3e-06 25.5 0.4 0.051 13.3 0.0 3.6 3 0 0 3 3 3 1 Thioredoxin domain TraF PF13728.1 KFM04683.1 - 0.00062 19.3 0.0 5.7 6.3 0.0 3.3 3 0 0 3 3 3 2 F plasmid transfer operon protein HyaE PF07449.6 KFM04683.1 - 0.00086 19.1 0.0 3.9 7.4 0.0 3.5 4 1 0 4 4 4 2 Hydrogenase-1 expression protein HyaE DUF2847 PF11009.3 KFM04683.1 - 0.0018 17.8 0.0 5.1 6.7 0.0 3.7 4 0 0 4 4 4 1 Protein of unknown function (DUF2847) Glutaredoxin PF00462.19 KFM04683.1 - 0.019 14.9 10.0 1.4 9.0 0.1 4.4 4 1 0 4 4 4 0 Glutaredoxin DUF836 PF05768.9 KFM04683.1 - 0.039 14.2 0.0 13 6.1 0.0 3.3 3 0 0 3 3 3 0 Glutaredoxin-like domain (DUF836) Thioredoxin_4 PF13462.1 KFM04683.1 - 0.073 13.0 6.2 3.7 7.5 0.3 3.6 2 1 1 4 4 4 0 Thioredoxin DSBA PF01323.15 KFM04683.1 - 0.62 9.5 4.6 17 4.8 0.1 4.2 3 3 2 5 5 5 0 DSBA-like thioredoxin domain Longin PF13774.1 KFM04684.1 - 3.2e-22 77.8 0.7 5.9e-22 77.0 0.5 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Guanylate_cyc PF00211.15 KFM04685.1 - 4.6e-121 400.9 3.0 6.7e-63 211.3 0.3 2.2 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain DUF1053 PF06327.9 KFM04685.1 - 7.5e-39 132.1 0.5 2.5e-38 130.4 0.3 2.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1053) HNOBA PF07701.9 KFM04685.1 - 0.0016 17.7 2.1 0.92 8.6 0.0 3.0 3 0 0 3 3 3 2 Heme NO binding associated PTPLA PF04387.9 KFM04686.1 - 5.9e-41 139.6 10.8 6.3e-41 139.5 7.5 1.0 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA RVT_1 PF00078.22 KFM04688.1 - 0.0011 18.3 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CCDC14 PF15254.1 KFM04689.1 - 0 1127.2 40.3 0 1127.1 27.9 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 14 DUF4152 PF13680.1 KFM04689.1 - 0.097 11.6 0.1 0.17 10.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4152) NEMO PF11577.3 KFM04689.1 - 1.3 8.7 18.0 1.1 9.0 1.3 3.0 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO Pkinase PF00069.20 KFM04690.1 - 5.6e-17 61.7 0.0 6.4e-17 61.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM04690.1 - 3e-06 26.5 0.0 3.9e-06 26.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase T2SK PF03934.8 KFM04690.1 - 0.076 12.1 0.0 0.094 11.8 0.0 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein K OMPdecase PF00215.19 KFM04691.1 - 7e-76 254.5 0.0 1.1e-75 253.8 0.0 1.3 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.22 KFM04691.1 - 1.2e-12 47.6 0.4 5.1e-12 45.5 0.1 2.3 3 1 0 3 3 3 1 Phosphoribosyl transferase domain Integrin_beta PF00362.13 KFM04692.1 - 1.1e-182 607.7 0.0 1.7e-182 607.0 0.0 1.2 1 0 0 1 1 1 1 Integrin, beta chain Integrin_b_cyt PF08725.6 KFM04692.1 - 5e-19 67.4 0.2 1.2e-18 66.2 0.1 1.6 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain Integrin_B_tail PF07965.7 KFM04692.1 - 4.5e-17 62.2 5.1 4.5e-17 62.2 3.5 4.4 5 0 0 5 5 5 1 Integrin beta tail domain EGF_2 PF07974.8 KFM04692.1 - 4.1e-09 36.4 92.7 0.00084 19.4 10.8 5.9 5 1 1 6 6 6 4 EGF-like domain hEGF PF12661.2 KFM04692.1 - 0.06 13.4 0.4 0.057 13.5 0.9 5.9 7 0 0 7 7 7 0 Human growth factor-like EGF LysE PF01810.13 KFM04692.1 - 0.16 11.2 0.4 0.27 10.4 0.3 1.2 1 0 0 1 1 1 0 LysE type translocator zf-H2C2_2 PF13465.1 KFM04694.1 - 6e-87 281.9 76.7 2.5e-09 36.9 0.1 14.3 13 2 0 13 13 13 12 Zinc-finger double domain zf-C2H2 PF00096.21 KFM04694.1 - 2.6e-84 272.7 85.6 1.2e-07 31.6 4.8 12.1 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM04694.1 - 1.9e-47 156.1 70.2 0.0003 20.9 1.0 12.1 12 0 0 12 12 12 12 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM04694.1 - 1.6e-33 113.5 68.3 1.8e-06 27.6 0.7 12.5 12 0 0 12 12 12 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM04694.1 - 1.8e-18 66.1 27.2 0.15 12.2 0.2 11.9 12 0 0 12 12 12 6 Zinc-finger double-stranded RNA-binding XPA_N PF01286.13 KFM04694.1 - 1e-07 31.4 52.5 6.8 6.4 0.1 12.0 12 0 0 12 12 12 4 XPA protein N-terminal Zn-ribbon_8 PF09723.5 KFM04694.1 - 6.9e-07 29.1 66.3 0.39 10.7 4.7 11.1 5 4 5 10 10 10 6 Zinc ribbon domain zf-TRAF PF02176.13 KFM04694.1 - 0.0023 18.2 35.4 0.19 12.1 0.3 6.0 5 1 1 6 6 6 3 TRAF-type zinc finger DNA_RNApol_7kD PF03604.8 KFM04694.1 - 0.0023 17.3 56.6 1.1 8.8 0.0 11.9 12 0 0 12 12 12 3 DNA directed RNA polymerase, 7 kDa subunit FYDLN_acid PF09538.5 KFM04694.1 - 0.018 15.6 25.5 6.4 7.4 0.2 8.1 4 4 5 9 9 9 0 Protein of unknown function (FYDLN_acid) Zn_ribbon_recom PF13408.1 KFM04694.1 - 0.056 13.7 68.0 3.5 7.9 1.4 10.6 5 3 5 10 10 10 0 Recombinase zinc beta ribbon domain C1_4 PF07975.7 KFM04694.1 - 0.072 13.1 41.4 0.67 10.0 2.2 8.9 3 3 7 10 10 10 0 TFIIH C1-like domain zf-LYAR PF08790.6 KFM04694.1 - 0.19 11.4 42.9 11 5.8 0.2 10.9 12 0 0 12 12 12 0 LYAR-type C2HC zinc finger zf-RING_3 PF14369.1 KFM04694.1 - 0.45 10.5 60.3 2.1 8.4 0.2 11.0 11 1 1 12 12 12 0 zinc-finger Mut7-C PF01927.11 KFM04694.1 - 1.8 8.5 35.7 0.47 10.4 0.5 6.8 3 3 3 6 6 6 0 Mut7-C RNAse domain zf-H2C2_2 PF13465.1 KFM04695.1 - 6.5e-71 231.3 73.1 2.1e-10 40.3 2.0 11.4 11 1 0 11 11 11 11 Zinc-finger double domain zf-C2H2 PF00096.21 KFM04695.1 - 1.3e-62 204.5 106.2 7.8e-08 32.2 3.2 11.1 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM04695.1 - 1.8e-38 128.0 93.8 1.6e-05 24.9 2.3 11.1 11 0 0 11 11 11 11 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM04695.1 - 1.8e-31 107.0 80.8 4.5e-05 23.2 0.1 11.2 11 0 0 11 11 11 11 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM04695.1 - 1e-12 47.7 56.9 0.039 14.1 0.7 11.1 11 0 0 11 11 11 4 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 KFM04695.1 - 7e-07 29.1 61.4 0.15 12.0 3.5 10.3 6 4 1 7 7 7 3 Zinc ribbon domain XPA_N PF01286.13 KFM04695.1 - 9.3e-06 25.2 44.2 3.4 7.4 0.1 10.6 11 0 0 11 11 11 2 XPA protein N-terminal FYDLN_acid PF09538.5 KFM04695.1 - 0.00032 21.2 13.4 9.7 6.8 0.3 8.3 4 3 4 8 8 8 0 Protein of unknown function (FYDLN_acid) DNA_RNApol_7kD PF03604.8 KFM04695.1 - 0.00072 18.9 47.5 3.8 7.0 0.1 10.6 11 0 0 11 11 11 2 DNA directed RNA polymerase, 7 kDa subunit C1_4 PF07975.7 KFM04695.1 - 0.005 16.8 43.3 0.16 12.0 0.9 8.6 2 2 7 9 9 9 1 TFIIH C1-like domain DUF2039 PF10217.4 KFM04695.1 - 0.02 14.8 0.8 0.02 14.8 0.6 4.1 3 2 0 4 4 4 0 Uncharacterized conserved protein (DUF2039) LIM PF00412.17 KFM04695.1 - 0.052 13.6 41.1 1.3 9.1 1.0 8.9 5 4 2 7 7 7 0 LIM domain YhfH PF14149.1 KFM04695.1 - 0.14 11.9 33.9 7.4 6.4 0.2 9.5 10 0 0 10 10 10 0 YhfH-like protein zf-C2HC_2 PF13913.1 KFM04695.1 - 0.14 11.8 0.3 0.14 11.8 0.2 10.7 11 2 0 11 11 11 0 zinc-finger of a C2HC-type zf-trcl PF13451.1 KFM04695.1 - 0.26 10.9 45.4 2.3 7.9 0.0 10.2 9 2 0 9 9 9 0 Probable zinc-binding domain OSTMP1 PF09777.4 KFM04695.1 - 0.43 9.7 0.0 0.43 9.7 0.0 3.1 3 0 0 3 3 3 0 Osteopetrosis-associated transmembrane protein 1 precursor Elf1 PF05129.8 KFM04695.1 - 0.62 9.8 28.9 0.35 10.5 0.2 6.9 1 1 9 10 10 10 0 Transcription elongation factor Elf1 like TFIIS_C PF01096.13 KFM04695.1 - 0.93 9.1 42.1 4.8 6.9 0.0 10.5 11 0 0 11 11 11 0 Transcription factor S-II (TFIIS) Prok-RING_1 PF14446.1 KFM04695.1 - 1.4 8.7 31.6 5.5 6.7 0.0 9.7 11 0 0 11 11 11 0 Prokaryotic RING finger family 1 PLATZ PF04640.9 KFM04695.1 - 2.7 8.2 11.5 4.7 7.4 0.1 4.9 4 1 2 6 6 4 0 PLATZ transcription factor DUF2256 PF10013.4 KFM04695.1 - 3.1 7.6 42.8 0.28 10.9 0.6 9.7 10 1 1 11 11 11 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn_ribbon_recom PF13408.1 KFM04695.1 - 3.5 7.9 64.3 9.3 6.6 2.8 8.7 3 3 5 8 8 8 0 Recombinase zinc beta ribbon domain HypA PF01155.14 KFM04695.1 - 4.7 6.9 35.2 0.83 9.3 0.8 5.7 1 1 5 7 7 7 0 Hydrogenase expression/synthesis hypA family zf-met PF12874.2 KFM04695.1 - 8.1 6.8 67.6 7 7.0 0.0 10.7 11 0 0 11 11 11 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 KFM04696.1 - 5.3e-76 247.4 97.5 1.1e-09 38.0 1.0 14.2 13 1 0 13 13 13 11 Zinc-finger double domain zf-C2H2 PF00096.21 KFM04696.1 - 1.8e-75 244.9 105.4 1.5e-08 34.4 1.7 12.9 12 1 1 13 13 12 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM04696.1 - 5.4e-43 142.1 78.8 2.7e-05 24.1 0.6 12.2 12 1 0 12 12 12 11 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM04696.1 - 2.9e-23 80.9 78.3 3.2e-05 23.6 0.2 12.6 13 1 0 13 13 11 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM04696.1 - 2.7e-12 46.4 39.1 0.54 10.4 0.1 11.0 11 0 0 11 11 11 6 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 KFM04696.1 - 5.4e-08 32.6 78.5 0.015 15.2 1.8 11.6 5 3 6 11 11 11 4 Zinc ribbon domain FYDLN_acid PF09538.5 KFM04696.1 - 0.00082 19.9 25.0 8.6 7.0 0.0 8.6 2 2 7 9 9 9 1 Protein of unknown function (FYDLN_acid) DNA_RNApol_7kD PF03604.8 KFM04696.1 - 0.002 17.5 67.1 0.87 9.1 0.1 12.8 13 0 0 13 13 13 5 DNA directed RNA polymerase, 7 kDa subunit zf-Di19 PF05605.7 KFM04696.1 - 0.0032 17.5 1.7 0.0032 17.5 1.1 6.9 5 4 2 7 7 7 1 Drought induced 19 protein (Di19), zinc-binding BolA PF01722.13 KFM04696.1 - 0.0046 16.8 15.6 1.3 8.9 0.0 6.0 4 2 1 5 5 5 1 BolA-like protein XPA_N PF01286.13 KFM04696.1 - 0.052 13.2 74.0 1.6 8.4 0.1 12.5 12 1 1 13 13 12 0 XPA protein N-terminal zf-trcl PF13451.1 KFM04696.1 - 0.74 9.4 0.0 0.74 9.4 0.0 11.4 8 4 2 10 10 10 0 Probable zinc-binding domain C1_4 PF07975.7 KFM04696.1 - 2.4 8.2 55.6 0.7 9.9 0.2 9.3 2 2 7 10 10 9 0 TFIIH C1-like domain PUCC PF03209.10 KFM04697.1 - 0.18 10.5 9.8 0.14 10.8 2.6 2.0 1 1 1 2 2 2 0 PUCC protein zf-H2C2_2 PF13465.1 KFM04698.1 - 3.1e-61 200.7 59.8 9.6e-09 35.1 1.0 9.0 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.21 KFM04698.1 - 2.1e-56 184.9 61.8 1.9e-08 34.1 0.4 8.1 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM04698.1 - 1.3e-31 106.6 53.6 6.6e-05 22.9 1.6 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM04698.1 - 6.5e-27 92.5 49.2 0.00011 21.9 0.0 8.1 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM04698.1 - 8.4e-14 51.2 28.9 0.04 14.0 0.0 8.0 8 0 0 8 8 8 6 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 KFM04698.1 - 5e-11 42.3 34.4 0.02 14.8 2.2 7.6 4 2 1 6 6 6 5 Zinc ribbon domain zf-LYAR PF08790.6 KFM04698.1 - 4.7e-07 29.3 24.8 1.1 9.0 0.3 8.1 8 0 0 8 8 8 2 LYAR-type C2HC zinc finger CpXC PF14353.1 KFM04698.1 - 6.1e-07 29.4 22.3 0.36 10.7 0.5 7.3 5 2 1 6 6 6 2 CpXC protein FYDLN_acid PF09538.5 KFM04698.1 - 2.7e-06 27.9 17.3 4.3 7.9 0.1 7.6 1 1 4 6 6 6 0 Protein of unknown function (FYDLN_acid) DZR PF12773.2 KFM04698.1 - 3.9e-06 26.5 28.4 0.12 12.1 2.1 5.0 2 2 1 3 3 3 2 Double zinc ribbon C1_3 PF07649.7 KFM04698.1 - 5.1e-06 26.4 21.2 7.7 6.6 0.0 8.0 8 0 0 8 8 8 0 C1-like domain XPA_N PF01286.13 KFM04698.1 - 0.00013 21.5 32.6 0.85 9.3 0.2 7.9 8 0 0 8 8 8 1 XPA protein N-terminal C1_4 PF07975.7 KFM04698.1 - 0.00013 21.8 28.8 4.1 7.4 1.8 6.8 1 1 5 7 7 7 0 TFIIH C1-like domain Prok-RING_1 PF14446.1 KFM04698.1 - 0.00028 20.5 19.1 14 5.5 0.0 7.7 7 1 0 7 7 7 0 Prokaryotic RING finger family 1 zinc_ribbon_2 PF13240.1 KFM04698.1 - 0.00039 19.7 43.0 0.032 13.7 4.4 6.4 6 1 0 6 6 6 3 zinc-ribbon domain zf-RING_3 PF14369.1 KFM04698.1 - 0.00092 19.1 35.1 0.96 9.5 0.1 7.7 7 1 1 8 8 8 1 zinc-finger Zn_Tnp_IS1595 PF12760.2 KFM04698.1 - 0.00094 18.9 42.8 0.21 11.3 1.6 5.7 4 2 1 5 5 5 2 Transposase zinc-ribbon domain Yippee-Mis18 PF03226.9 KFM04698.1 - 0.0014 18.6 17.9 1.8 8.6 2.3 5.2 4 2 1 5 5 5 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly AAA_22 PF13401.1 KFM04698.1 - 0.0026 17.9 0.2 4.4 7.4 0.0 3.3 4 0 0 4 4 2 0 AAA domain DNA_RNApol_7kD PF03604.8 KFM04698.1 - 0.005 16.2 27.7 1.2 8.7 0.1 7.7 8 0 0 8 8 8 1 DNA directed RNA polymerase, 7 kDa subunit zf-ISL3 PF14690.1 KFM04698.1 - 0.0051 16.8 38.1 2.7 8.0 0.6 8.1 8 0 0 8 8 8 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-Di19 PF05605.7 KFM04698.1 - 0.006 16.6 36.5 0.15 12.2 3.0 5.7 1 1 3 6 6 5 3 Drought induced 19 protein (Di19), zinc-binding DUF164 PF02591.10 KFM04698.1 - 0.013 15.3 20.7 16 5.4 0.0 7.2 7 1 1 8 8 8 0 Putative zinc ribbon domain LIM PF00412.17 KFM04698.1 - 0.014 15.4 28.1 0.26 11.4 1.3 5.9 2 1 2 5 5 5 0 LIM domain zf-met PF12874.2 KFM04698.1 - 0.017 15.3 45.1 0.23 11.6 0.1 7.5 8 0 0 8 8 7 0 Zinc-finger of C2H2 type zf-ribbon_3 PF13248.1 KFM04698.1 - 0.033 13.4 45.5 0.39 9.9 0.2 8.0 8 0 0 8 8 8 0 zinc-ribbon domain Zn_ribbon_recom PF13408.1 KFM04698.1 - 0.033 14.4 28.5 2.2 8.5 0.7 6.1 2 2 2 5 5 5 0 Recombinase zinc beta ribbon domain zf-C2HC_2 PF13913.1 KFM04698.1 - 0.04 13.5 31.4 0.17 11.5 0.1 7.1 7 0 0 7 7 7 0 zinc-finger of a C2HC-type UPF0547 PF10571.4 KFM04698.1 - 0.054 13.2 42.3 1.7 8.4 0.2 7.9 8 0 0 8 8 8 0 Uncharacterised protein family UPF0547 zf-DNA_Pol PF08996.5 KFM04698.1 - 0.057 12.7 18.9 0.25 10.6 0.2 4.0 1 1 2 4 4 4 0 DNA Polymerase alpha zinc finger YhfH PF14149.1 KFM04698.1 - 0.062 13.0 31.6 16 5.3 0.0 8.0 8 0 0 8 8 8 0 YhfH-like protein DUF329 PF03884.9 KFM04698.1 - 0.088 12.3 23.8 9 5.9 0.1 7.1 8 0 0 8 8 8 0 Domain of unknown function (DUF329) zf-trcl PF13451.1 KFM04698.1 - 0.13 11.9 26.0 7.8 6.2 0.1 7.5 8 0 0 8 8 8 0 Probable zinc-binding domain COX5B PF01215.14 KFM04698.1 - 0.14 11.8 26.6 11 5.6 0.1 7.5 1 1 7 8 8 8 0 Cytochrome c oxidase subunit Vb zinc-ribbons_6 PF07191.7 KFM04698.1 - 0.15 11.8 23.0 0.21 11.4 0.9 5.3 1 1 3 5 5 5 0 zinc-ribbons HypA PF01155.14 KFM04698.1 - 0.17 11.5 24.8 4.1 7.1 2.9 5.1 1 1 3 4 4 4 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_5 PF13719.1 KFM04698.1 - 0.27 10.8 33.5 5.2 6.7 2.8 7.8 7 1 1 8 8 8 0 zinc-ribbon domain Ribosomal_L34e PF01199.13 KFM04698.1 - 0.39 10.9 17.6 1.9 8.7 0.3 4.7 1 1 4 5 5 5 0 Ribosomal protein L34e zf-IS66 PF13005.2 KFM04698.1 - 0.5 10.3 28.9 10 6.2 0.0 7.9 7 1 2 9 9 9 0 zinc-finger binding domain of transposase IS66 RRN7 PF11781.3 KFM04698.1 - 0.67 9.5 21.3 16 5.1 0.1 7.3 8 0 0 8 8 8 0 RNA polymerase I-specific transcription initiation factor Rrn7 zinc_ribbon_4 PF13717.1 KFM04698.1 - 0.83 9.4 32.4 7.7 6.2 2.6 7.7 7 1 1 8 8 8 0 zinc-ribbon domain GAGA PF09237.6 KFM04698.1 - 1.3 8.6 21.0 3.5 7.2 0.0 6.1 2 2 5 7 7 7 0 GAGA factor DUF2688 PF10892.3 KFM04698.1 - 1.5 8.5 20.3 61 3.3 0.1 7.2 7 1 1 8 8 8 0 Protein of unknown function (DUF2688) DUF899 PF05988.7 KFM04698.1 - 1.5 8.2 5.5 26 4.1 0.1 3.3 1 1 1 4 4 4 0 Bacterial protein of unknown function (DUF899) TFIIS_C PF01096.13 KFM04698.1 - 1.7 8.3 35.1 7.6 6.2 0.1 7.9 7 1 0 7 7 7 0 Transcription factor S-II (TFIIS) DUF1610 PF07754.6 KFM04698.1 - 2.6 8.2 60.1 0.48 10.5 1.3 7.9 8 0 0 8 8 8 0 Domain of unknown function (DUF1610) A2L_zn_ribbon PF08792.5 KFM04698.1 - 4.2 6.9 40.1 4.2 6.9 0.1 8.0 8 0 0 8 8 8 0 A2L zinc ribbon domain Terminase_GpA PF05876.7 KFM04698.1 - 4.5 5.4 23.6 1.3 7.3 1.2 3.8 1 1 3 4 4 4 0 Phage terminase large subunit (GpA) DUF2072 PF09845.4 KFM04698.1 - 6.1 6.7 31.3 5.7 6.8 1.5 6.1 5 3 0 5 5 5 0 Zn-ribbon containing protein (DUF2072) zf-UBP PF02148.14 KFM04698.1 - 7.6 6.7 34.9 47 4.1 3.8 6.6 1 1 3 4 4 3 0 Zn-finger in ubiquitin-hydrolases and other protein zf-HIT PF04438.11 KFM04698.1 - 8.5 6.1 39.3 0.8 9.4 0.4 7.5 8 0 0 8 8 8 0 HIT zinc finger FIST PF08495.5 KFM04699.1 - 0.18 10.9 1.6 0.14 11.2 0.1 1.5 2 0 0 2 2 2 0 FIST N domain Pkinase PF00069.20 KFM04700.1 - 8.7e-46 156.1 0.1 1.9e-45 155.0 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM04700.1 - 9.4e-30 103.5 0.0 2.4e-29 102.2 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase IKKbetaNEMObind PF12179.3 KFM04700.1 - 1.9e-16 59.5 3.4 1.9e-16 59.5 2.4 2.3 2 0 0 2 2 2 1 I-kappa-kinase-beta NEMO binding domain Kdo PF06293.9 KFM04700.1 - 6.9e-05 22.0 0.0 0.0002 20.4 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFM04700.1 - 0.0027 17.4 0.0 0.0061 16.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KFM04700.1 - 0.0092 15.3 0.0 0.021 14.1 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Reprolysin PF01421.14 KFM04701.1 - 4.6e-67 225.4 0.0 8.4e-67 224.6 0.0 1.4 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.14 KFM04701.1 - 3.6e-25 88.2 0.2 5.6e-25 87.6 0.2 1.3 1 0 0 1 1 1 1 Reprolysin family propeptide Disintegrin PF00200.18 KFM04701.1 - 3.4e-24 84.8 31.1 3.4e-24 84.8 21.6 2.4 1 1 1 2 2 2 1 Disintegrin Reprolysin_5 PF13688.1 KFM04701.1 - 3.6e-18 66.2 0.0 7.8e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KFM04701.1 - 7.2e-16 58.8 0.0 1.2e-15 58.0 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFM04701.1 - 6.5e-13 49.1 0.0 9.9e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM_CR PF08516.7 KFM04701.1 - 2.7e-11 43.5 3.8 2.7e-11 43.5 2.6 2.5 2 1 0 2 2 2 1 ADAM cysteine-rich Reprolysin_4 PF13583.1 KFM04701.1 - 7.2e-10 38.7 0.0 1.3e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KFM04701.1 - 0.0094 15.6 0.1 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.4 KFM04701.1 - 0.11 11.3 0.1 0.17 10.7 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Spc97_Spc98 PF04130.8 KFM04702.1 - 9.1e-125 417.0 12.8 9.1e-125 417.0 8.8 1.5 2 0 0 2 2 2 1 Spc97 / Spc98 family DUF629 PF04780.7 KFM04703.1 - 0.098 11.1 0.1 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-C2H2_4 PF13894.1 KFM04703.1 - 0.14 12.5 0.1 0.25 11.7 0.1 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger PRAP PF15314.1 KFM04704.1 - 3.1e-11 43.3 8.4 3.9e-11 43.0 5.8 1.3 1 0 0 1 1 1 1 Proline-rich acidic protein 1, pregnancy-specific uterine ECH PF00378.15 KFM04705.1 - 2.9e-64 216.5 1.0 3.2e-64 216.3 0.7 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 KFM04705.1 - 0.028 14.1 0.1 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S49 MMR_HSR1 PF01926.18 KFM04706.1 - 7.7e-13 48.4 0.0 1.2e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFM04706.1 - 1.1e-06 28.0 0.0 0.0002 20.7 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 KFM04706.1 - 0.0003 20.0 0.7 0.0012 18.0 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 KFM04706.1 - 0.00041 19.8 0.0 0.41 10.1 0.0 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 KFM04706.1 - 0.0022 18.1 0.0 0.14 12.3 0.0 2.3 1 1 1 2 2 2 1 AAA domain Dynamin_N PF00350.18 KFM04706.1 - 0.0027 17.5 0.6 0.36 10.6 0.1 2.3 1 1 1 2 2 2 1 Dynamin family AAA_16 PF13191.1 KFM04706.1 - 0.0039 17.2 1.5 0.031 14.2 0.1 2.5 2 1 0 3 3 3 1 AAA ATPase domain IIGP PF05049.8 KFM04706.1 - 0.0043 15.9 0.0 0.006 15.4 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) GTP_EFTU PF00009.22 KFM04706.1 - 0.0045 16.4 0.1 1.9 7.8 0.0 2.6 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.11 KFM04706.1 - 0.0059 15.7 0.0 0.0091 15.1 0.0 1.3 1 0 0 1 1 1 1 AIG1 family MobB PF03205.9 KFM04706.1 - 0.02 14.5 0.5 0.11 12.2 0.1 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 KFM04706.1 - 0.022 14.3 0.1 4.3 6.7 0.0 2.8 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein SRPRB PF09439.5 KFM04706.1 - 0.069 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Miro PF08477.8 KFM04706.1 - 0.089 13.2 0.0 0.28 11.6 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein Ras PF00071.17 KFM04706.1 - 0.12 11.7 0.0 1.2 8.4 0.0 2.2 2 0 0 2 2 2 0 Ras family AAA_18 PF13238.1 KFM04706.1 - 0.14 12.4 0.1 0.25 11.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain Abhydrolase_1 PF00561.15 KFM04707.1 - 1e-22 80.8 0.3 1.6e-22 80.2 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.11 KFM04707.1 - 3.8e-20 71.0 0.0 8.4e-20 69.9 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 KFM04707.1 - 1.5e-10 41.3 0.5 2.2e-10 40.8 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFM04707.1 - 5.3e-09 35.9 0.0 1.2e-08 34.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family VirJ PF06057.6 KFM04707.1 - 0.0057 16.4 0.0 0.0088 15.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Cutinase PF01083.17 KFM04707.1 - 0.011 15.4 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Cutinase DUF2974 PF11187.3 KFM04707.1 - 0.095 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Lipase_2 PF01674.13 KFM04707.1 - 0.097 11.9 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) Abhydro_lipase PF04083.11 KFM04708.1 - 8.5e-20 69.8 0.0 2.2e-19 68.5 0.0 1.7 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 KFM04708.1 - 3.3e-14 53.0 0.0 1.1e-13 51.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFM04708.1 - 5e-06 26.3 0.0 4.6e-05 23.2 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFM04708.1 - 5.9e-05 23.0 0.0 0.00015 21.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family RE_NgoFVII PF09565.5 KFM04708.1 - 0.15 10.9 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 NgoFVII restriction endonuclease Abhydro_lipase PF04083.11 KFM04709.1 - 3e-16 58.5 0.0 7.7e-16 57.2 0.0 1.8 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 KFM04709.1 - 2.1e-13 50.3 0.1 6.7e-13 48.7 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFM04709.1 - 7.8e-08 32.1 0.0 2.2e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFM04709.1 - 1.1e-07 31.9 0.1 2.6e-07 30.7 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Kelch_5 PF13854.1 KFM04709.1 - 0.019 14.9 0.1 0.1 12.5 0.0 2.2 3 0 0 3 3 3 0 Kelch motif Amino_oxidase PF01593.19 KFM04711.1 - 1.3e-05 24.5 0.0 0.017 14.2 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase PTEN_C2 PF10409.4 KFM04712.1 - 4e-44 149.5 3.2 6.3e-44 148.9 2.2 1.3 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.15 KFM04712.1 - 9.4e-09 34.9 0.0 4.2e-08 32.8 0.0 2.0 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFM04712.1 - 3.1e-05 23.4 0.0 7.6e-05 22.1 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KFM04712.1 - 0.001 19.3 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KFM04712.1 - 0.0051 16.8 0.0 0.014 15.4 0.0 1.8 1 1 0 1 1 1 1 Inositol hexakisphosphate DUF3256 PF11644.3 KFM04712.1 - 0.02 14.3 0.3 0.052 13.0 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3256) AAA PF00004.24 KFM04713.1 - 1e-36 126.0 0.0 3.1e-36 124.5 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFM04713.1 - 1.5e-06 28.3 0.1 0.00054 20.1 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFM04713.1 - 1.2e-05 26.0 0.1 4.7e-05 24.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KFM04713.1 - 1.4e-05 24.2 0.0 4.8e-05 22.5 0.0 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KFM04713.1 - 2e-05 24.6 0.6 0.0016 18.4 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 KFM04713.1 - 3e-05 23.9 0.0 5.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFM04713.1 - 0.00011 21.9 0.1 0.0012 18.5 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KFM04713.1 - 0.00017 21.0 1.9 0.26 10.6 0.0 2.6 2 1 0 3 3 3 2 AAA domain Mg_chelatase PF01078.16 KFM04713.1 - 0.0021 17.2 0.0 0.023 13.8 0.0 2.3 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 KFM04713.1 - 0.0025 17.7 0.0 0.0047 16.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain DEAD PF00270.24 KFM04713.1 - 0.0029 17.1 0.2 0.28 10.6 0.0 2.5 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_18 PF13238.1 KFM04713.1 - 0.0069 16.6 0.6 0.038 14.2 0.0 2.5 3 1 0 3 3 3 1 AAA domain SKI PF01202.17 KFM04713.1 - 0.01 15.7 0.0 0.027 14.3 0.0 1.7 1 0 0 1 1 1 0 Shikimate kinase AAA_2 PF07724.9 KFM04713.1 - 0.01 15.7 0.0 0.039 13.8 0.0 2.0 2 1 0 2 2 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 KFM04713.1 - 0.011 15.1 0.3 0.032 13.6 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Rad17 PF03215.10 KFM04713.1 - 0.012 14.3 0.2 0.023 13.4 0.1 1.8 1 1 0 1 1 1 0 Rad17 cell cycle checkpoint protein Zeta_toxin PF06414.7 KFM04713.1 - 0.012 14.7 0.0 0.053 12.6 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.17 KFM04713.1 - 0.019 15.1 0.0 0.04 14.0 0.0 1.7 1 1 0 1 1 1 0 RNA helicase PhoH PF02562.11 KFM04713.1 - 0.027 13.7 0.1 0.34 10.0 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activ_2 PF14532.1 KFM04713.1 - 0.028 14.4 0.2 0.31 11.1 0.0 2.7 3 1 0 3 3 2 0 Sigma-54 interaction domain AAA_19 PF13245.1 KFM04713.1 - 0.034 13.8 0.1 0.072 12.8 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_24 PF13479.1 KFM04713.1 - 0.043 13.3 0.1 0.13 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 KFM04713.1 - 0.045 12.4 0.0 0.094 11.4 0.0 1.6 1 0 0 1 1 1 0 TIP49 C-terminus AAA_28 PF13521.1 KFM04713.1 - 0.058 13.3 0.8 0.88 9.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain Bac_DnaA PF00308.13 KFM04713.1 - 0.076 12.6 0.0 0.32 10.5 0.0 2.0 1 1 0 1 1 1 0 Bacterial dnaA protein Arch_ATPase PF01637.13 KFM04713.1 - 0.078 12.6 0.0 0.37 10.4 0.0 2.0 1 1 1 2 2 2 0 Archaeal ATPase AAA_10 PF12846.2 KFM04713.1 - 0.1 11.9 0.3 6.3 6.1 0.0 2.8 2 1 0 2 2 2 0 AAA-like domain KaiC PF06745.8 KFM04713.1 - 0.11 11.5 0.3 0.97 8.5 0.0 2.5 1 1 1 2 2 2 0 KaiC AAA_21 PF13304.1 KFM04713.1 - 0.12 12.2 0.7 1.6 8.5 0.0 2.4 3 0 0 3 3 3 0 AAA domain APS_kinase PF01583.15 KFM04714.1 - 9.9e-74 246.2 0.0 1.6e-73 245.5 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.12 KFM04714.1 - 1.5e-66 223.7 0.0 2.1e-66 223.3 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 KFM04714.1 - 1e-49 168.0 0.0 1.7e-49 167.2 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.1 KFM04714.1 - 1.4e-07 31.4 0.0 2.5e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFM04714.1 - 2.2e-06 28.5 0.0 6.4e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFM04714.1 - 0.00012 22.3 0.0 0.0003 21.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KFM04714.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 His_Phos_2 PF00328.17 KFM04715.1 - 5.5e-19 68.6 0.1 7e-19 68.3 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PAP2_C PF14360.1 KFM04716.1 - 1.4e-30 105.3 14.4 1.4e-30 105.3 10.0 2.4 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.16 KFM04716.1 - 3.3e-06 26.8 8.8 3.3e-06 26.8 6.1 1.9 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 KFM04716.1 - 6.4e-05 22.5 6.4 6.4e-05 22.5 4.5 1.7 1 1 1 2 2 2 1 PAP2 superfamily SAM_1 PF00536.25 KFM04716.1 - 0.00011 22.2 0.0 0.00033 20.7 0.0 1.8 1 1 1 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFM04716.1 - 0.0051 16.6 0.0 0.0095 15.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 KFM04716.1 - 0.13 12.0 0.2 0.13 12.0 0.1 2.9 3 1 0 3 3 3 0 Sterile alpha motif (SAM)/Pointed domain Ceramidase_alk PF04734.8 KFM04717.1 - 3.9e-270 897.5 0.0 4.3e-270 897.3 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase RRM_1 PF00076.17 KFM04718.1 - 2.2e-40 136.1 1.5 3.9e-17 61.6 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM04718.1 - 3.9e-32 110.0 0.5 1.7e-10 40.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DND1_DSRM PF14709.1 KFM04718.1 - 5.2e-30 103.5 0.1 1.2e-29 102.3 0.1 1.7 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 RRM_5 PF13893.1 KFM04718.1 - 9e-23 79.8 0.4 2.1e-08 33.8 0.2 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KFM04718.1 - 0.0006 19.5 0.1 0.23 11.2 0.0 2.6 2 0 0 2 2 2 2 Limkain b1 dsrm PF00035.20 KFM04718.1 - 0.15 12.6 0.6 7.1 7.2 0.0 3.1 3 0 0 3 3 3 0 Double-stranded RNA binding motif IncA PF04156.9 KFM04720.1 - 0.021 14.4 0.9 0.023 14.3 0.7 1.2 1 0 0 1 1 1 0 IncA protein Med4 PF10018.4 KFM04720.1 - 0.035 13.4 0.1 0.044 13.1 0.1 1.3 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Viral_env_E26 PF11050.3 KFM04720.1 - 0.039 13.1 0.0 0.048 12.8 0.0 1.2 1 0 0 1 1 1 0 Virus envelope protein E26 DUF641 PF04859.7 KFM04720.1 - 0.055 13.2 0.6 0.11 12.2 0.4 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Atg14 PF10186.4 KFM04720.1 - 0.12 11.2 0.3 0.14 11.0 0.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TMF_DNA_bd PF12329.3 KFM04720.1 - 0.19 11.5 3.6 0.25 11.1 0.8 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Med9 PF07544.8 KFM04720.1 - 0.53 10.0 2.9 1.3 8.8 2.0 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Syntaphilin PF15290.1 KFM04720.1 - 3.5 7.0 5.3 3.2 7.1 2.9 1.5 2 0 0 2 2 2 0 Golgi-localised syntaxin-1-binding clamp Sugarporin_N PF11471.3 KFM04720.1 - 7.2 6.3 7.0 12 5.5 4.8 1.3 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Pkinase PF00069.20 KFM04721.1 - 6.3e-69 232.0 0.0 8.6e-69 231.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.24 KFM04721.1 - 1.6e-36 124.0 0.1 1.5e-21 75.9 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.12 KFM04721.1 - 5.2e-36 124.0 0.0 8.1e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM04721.1 - 1.6e-05 24.0 0.0 2.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFM04721.1 - 0.031 13.9 0.0 0.34 10.6 0.0 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase_C PF00433.19 KFM04721.1 - 0.045 14.2 4.0 0.16 12.5 2.8 2.0 1 0 0 1 1 1 0 Protein kinase C terminal domain Prokineticin PF06607.6 KFM04722.1 - 0.00029 20.8 6.2 0.00041 20.3 4.3 1.3 1 0 0 1 1 1 1 Prokineticin UPF0506 PF11703.3 KFM04722.1 - 4 7.4 13.3 2.3 8.2 1.4 3.2 1 1 2 3 3 3 0 UPF0506 Cadherin PF00028.12 KFM04724.1 - 1.4e-122 400.2 21.9 5e-18 65.1 0.1 10.8 10 0 0 10 10 10 10 Cadherin domain Cadherin_2 PF08266.7 KFM04724.1 - 1e-08 34.6 0.0 0.11 12.0 0.0 5.2 4 0 0 4 4 4 3 Cadherin-like IPK PF03770.11 KFM04726.1 - 2.8e-68 229.4 0.3 5.4e-68 228.5 0.2 1.5 1 1 0 1 1 1 1 Inositol polyphosphate kinase GPAT_N PF14829.1 KFM04726.1 - 0.098 12.3 0.0 0.4 10.4 0.0 2.0 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase N-terminal TMP-TENI PF02581.12 KFM04726.1 - 0.14 11.2 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI zf-CDGSH PF09360.5 KFM04727.1 - 3e-12 46.1 0.5 4.9e-12 45.4 0.4 1.3 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type MitoNEET_N PF10660.4 KFM04727.1 - 2.9e-09 36.6 0.5 4.1e-09 36.1 0.3 1.2 1 0 0 1 1 1 1 Iron-containing outer mitochondrial membrane protein N-terminus Gag_p30 PF02093.11 KFM04728.1 - 1.6e-22 79.7 0.1 2e-22 79.4 0.1 1.0 1 0 0 1 1 1 1 Gag P30 core shell protein Gag_p24 PF00607.15 KFM04728.1 - 4.3e-05 23.1 0.3 9.3e-05 22.0 0.2 1.5 1 1 0 1 1 1 1 gag gene protein p24 (core nucleocapsid protein) FlgM PF04316.8 KFM04728.1 - 0.13 12.2 0.1 2.2 8.2 0.0 2.3 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM GED PF02212.13 KFM04728.1 - 0.13 12.1 0.1 0.48 10.3 0.0 1.8 2 0 0 2 2 2 0 Dynamin GTPase effector domain UQ_con PF00179.21 KFM04729.1 - 1.6e-49 166.9 0.0 1.7e-49 166.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFM04729.1 - 8e-05 22.4 0.0 9.1e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KFM04729.1 - 0.00057 19.7 0.0 0.00063 19.6 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KFM04729.1 - 0.04 13.5 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 UEV domain HMG_box PF00505.14 KFM04730.1 - 5.6e-26 90.6 23.1 9e-20 70.7 4.4 3.2 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.5 KFM04730.1 - 1.3e-18 67.1 21.9 6.5e-10 39.2 4.3 3.3 3 1 0 3 3 3 2 HMG-box domain YABBY PF04690.8 KFM04730.1 - 0.019 15.2 0.3 0.019 15.2 0.2 2.8 1 1 2 3 3 3 0 YABBY protein PSI_PsaF PF02507.10 KFM04730.1 - 0.12 11.8 1.2 0.29 10.6 0.9 1.6 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III DnaJ PF00226.26 KFM04731.1 - 0.013 15.1 0.6 0.052 13.2 0.0 2.2 2 0 0 2 2 2 0 DnaJ domain DUF4407 PF14362.1 KFM04731.1 - 0.14 11.0 1.6 0.18 10.7 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Prefoldin_2 PF01920.15 KFM04731.1 - 0.61 9.8 7.2 4.2 7.1 2.0 2.8 2 1 0 2 2 2 0 Prefoldin subunit DUF4200 PF13863.1 KFM04731.1 - 9.3 6.2 14.0 3.6 7.5 1.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) DUF3719 PF12516.3 KFM04732.1 - 5e-19 67.6 0.6 1.3e-17 63.1 0.1 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3719) P4Ha_N PF08336.6 KFM04733.1 - 3.3e-44 149.9 0.1 3.3e-44 149.9 0.1 1.6 2 0 0 2 2 2 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy PF03171.15 KFM04733.1 - 5.5e-13 49.0 0.0 1.2e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KFM04733.1 - 1.5e-06 28.6 0.0 3.5e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fis1_TPR_C PF14853.1 KFM04733.1 - 0.0017 18.2 0.5 0.017 14.9 0.4 2.6 1 1 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.12 KFM04733.1 - 0.058 13.3 0.8 0.41 10.6 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 KFM04733.1 - 0.13 12.2 0.6 0.3 11.0 0.4 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat PLA2G12 PF06951.6 KFM04734.1 - 1.9e-89 298.2 8.4 2.2e-89 298.0 5.8 1.0 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) Zona_pellucida PF00100.18 KFM04735.1 - 2.6e-44 151.6 0.2 2.6e-44 151.6 0.1 1.7 2 0 0 2 2 2 1 Zona pellucida-like domain FXa_inhibition PF14670.1 KFM04735.1 - 3.9e-18 65.2 30.4 3.5e-11 43.0 7.8 4.8 6 0 0 6 6 6 2 Coagulation Factor Xa inhibitory site cEGF PF12662.2 KFM04735.1 - 3.6e-05 23.2 16.8 0.0062 16.1 0.3 4.3 3 0 0 3 3 3 3 Complement Clr-like EGF-like DUF607 PF04678.8 KFM04736.1 - 1.9e-64 216.8 1.0 2.4e-64 216.5 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF607 DUF2960 PF11173.3 KFM04736.1 - 0.031 14.5 0.0 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2960) SPX PF03105.14 KFM04736.1 - 0.15 11.7 1.0 0.17 11.6 0.1 1.5 2 0 0 2 2 2 0 SPX domain Pkinase_Tyr PF07714.12 KFM04737.1 - 8.7e-91 303.5 0.0 1.7e-90 302.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Focal_AT PF03623.8 KFM04737.1 - 2.4e-62 208.5 3.8 4.5e-62 207.6 2.6 1.4 1 0 0 1 1 1 1 Focal adhesion targeting region Pkinase PF00069.20 KFM04737.1 - 1.4e-43 148.9 0.0 3e-43 147.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain FERM_M PF00373.13 KFM04737.1 - 2e-11 44.1 2.4 2e-11 44.1 1.7 1.8 2 0 0 2 2 2 1 FERM central domain Neur_chan_memb PF02932.11 KFM04738.1 - 7.7e-82 274.7 14.9 1.6e-58 198.3 8.2 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 KFM04738.1 - 1.1e-77 260.0 3.8 1.4e-77 259.7 2.6 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Abhydrolase_6 PF12697.2 KFM04739.1 - 1.1e-34 120.3 0.2 2.1e-34 119.4 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFM04739.1 - 3.7e-28 98.6 0.0 1.3e-27 96.8 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold HAD_2 PF13419.1 KFM04739.1 - 1.3e-16 61.3 0.0 2.7e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Abhydrolase_5 PF12695.2 KFM04739.1 - 4e-15 55.8 0.0 1.8e-14 53.7 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_like PF13242.1 KFM04739.1 - 1.6e-06 27.7 0.0 3e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_4 PF12146.3 KFM04739.1 - 4.1e-05 23.3 0.0 9e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 KFM04739.1 - 0.012 14.1 0.0 0.018 13.5 0.0 1.2 1 0 0 1 1 1 0 Ndr family Hydrolase PF00702.21 KFM04739.1 - 0.018 15.4 0.0 0.034 14.5 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Pkinase PF00069.20 KFM04740.1 - 6.7e-39 133.6 0.0 9.1e-39 133.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM04740.1 - 7.8e-32 110.3 0.0 1.1e-31 109.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KFM04740.1 - 0.017 14.4 0.0 0.033 13.5 0.0 1.4 1 1 0 1 1 1 0 RIO1 family Acetyltransf_13 PF13880.1 KFM04741.1 - 2.8e-31 107.0 0.0 6.2e-31 105.9 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 KFM04741.1 - 6.4e-18 64.0 0.7 1.7e-17 62.6 0.5 1.8 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO DUF814 PF05670.8 KFM04742.1 - 4e-26 90.7 0.1 4.8e-26 90.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF814) YscJ_FliF PF01514.12 KFM04742.1 - 0.12 11.5 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Secretory protein of YscJ/FliF family WEMBL PF05701.6 KFM04743.1 - 0.00052 18.5 5.2 0.00062 18.3 2.2 1.8 1 1 1 2 2 2 1 Weak chloroplast movement under blue light NPV_P10 PF05531.7 KFM04743.1 - 0.0035 17.5 8.1 0.48 10.6 0.1 4.9 2 1 4 6 6 6 1 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 KFM04743.1 - 0.0073 16.1 10.5 4 7.2 0.0 4.5 2 1 3 5 5 5 2 Protein of unknown function (DUF1664) Myosin_tail_1 PF01576.14 KFM04743.1 - 0.0091 13.7 9.6 0.17 9.5 1.4 2.1 2 0 0 2 2 2 2 Myosin tail MCPsignal PF00015.16 KFM04743.1 - 0.011 15.2 7.8 0.16 11.4 0.2 3.1 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Reo_sigmaC PF04582.7 KFM04743.1 - 0.015 14.4 12.6 0.36 9.9 2.6 3.2 1 1 2 3 3 3 0 Reovirus sigma C capsid protein CotJB PF12652.2 KFM04743.1 - 0.025 14.6 0.3 0.12 12.4 0.1 2.3 2 0 0 2 2 2 0 CotJB protein ADIP PF11559.3 KFM04743.1 - 0.03 14.2 0.2 0.03 14.2 0.1 3.1 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF869 PF05911.6 KFM04743.1 - 0.19 9.9 11.4 0.54 8.4 8.0 1.6 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) Syntaxin PF00804.20 KFM04743.1 - 1.6 8.9 15.2 8.8 6.5 4.2 4.0 1 1 1 3 3 3 0 Syntaxin DNA_repr_REX1B PF14966.1 KFM04743.1 - 3.5 8.0 8.3 5 7.5 0.4 3.9 2 1 2 4 4 4 0 DNA repair REX1-B Takusan PF04822.8 KFM04743.1 - 6.1 6.6 9.3 0.14 11.9 0.4 2.9 4 0 0 4 4 4 0 Takusan DUF914 PF06027.7 KFM04744.1 - 5.2e-14 51.8 2.4 9.2e-13 47.7 0.1 2.0 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 KFM04744.1 - 9.9e-11 41.7 18.8 1.7e-09 37.8 2.0 2.8 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.10 KFM04744.1 - 3.3e-10 39.5 0.4 5.3e-10 38.8 0.3 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 KFM04744.1 - 9.8e-09 35.0 10.3 0.00013 21.6 1.5 2.4 2 1 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 KFM04744.1 - 3.8e-06 26.0 1.6 5.1e-06 25.6 1.1 1.2 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.1 KFM04744.1 - 4.5e-06 26.8 1.7 4.5e-06 26.8 1.2 3.0 2 1 1 3 3 3 1 Multidrug resistance efflux transporter Bax1-I PF01027.15 KFM04744.1 - 1.6e-05 24.6 1.8 1.6e-05 24.6 1.3 2.2 1 1 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 Mg_trans_NIPA PF05653.9 KFM04744.1 - 0.0025 16.8 1.1 0.0046 15.9 0.7 1.4 1 0 0 1 1 1 1 Magnesium transporter NIPA DUF4184 PF13803.1 KFM04744.1 - 0.019 14.3 2.8 0.16 11.2 0.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4184) UPF0546 PF10639.4 KFM04744.1 - 0.43 10.4 5.9 1.5 8.6 0.8 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 Ion_trans_2 PF07885.11 KFM04745.1 - 5.9e-27 93.2 12.3 5.3e-17 61.3 5.4 2.4 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.26 KFM04745.1 - 1 8.5 9.3 4.7 6.4 6.7 2.0 1 1 1 2 2 2 0 Ion transport protein zf-DHHC PF01529.15 KFM04745.1 - 5.6 6.3 7.3 5.4 6.3 4.1 1.6 1 1 0 1 1 1 0 DHHC palmitoyltransferase Mur_ligase_M PF08245.7 KFM04746.1 - 0.13 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Mur ligase middle domain Thiolase_N PF00108.18 KFM04747.1 - 4.2e-89 298.0 0.3 5.5e-89 297.6 0.2 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KFM04747.1 - 2.8e-50 168.8 0.0 5.8e-50 167.8 0.0 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KFM04747.1 - 1.4e-07 31.2 0.7 1.4e-07 31.2 0.5 2.6 3 1 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.5 KFM04747.1 - 0.15 12.1 1.1 0.94 9.5 0.0 2.7 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 KFM04747.1 - 0.2 11.3 4.2 1.1 9.0 0.2 2.8 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ECH PF00378.15 KFM04748.1 - 5.6e-80 267.9 0.1 8.6e-80 267.3 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family 3HCDH_N PF02737.13 KFM04748.1 - 3.2e-56 189.8 1.3 6.4e-56 188.8 0.9 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KFM04748.1 - 2.8e-26 91.7 0.1 9.4e-26 90.0 0.1 2.0 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Ras PF00071.17 KFM04749.1 - 4.1e-51 172.5 0.2 4.7e-51 172.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM04749.1 - 3.1e-13 50.2 0.0 4.8e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM04749.1 - 1.5e-10 40.6 0.4 2.1e-10 40.1 0.2 1.2 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFM04749.1 - 6.8e-05 22.3 0.0 8.9e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFM04749.1 - 0.0065 15.6 0.1 0.0079 15.3 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF2361 PF10153.4 KFM04749.1 - 0.021 14.9 0.2 0.032 14.4 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) DUF3963 PF13124.1 KFM04749.1 - 0.091 12.5 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) Kinesin PF00225.18 KFM04751.1 - 1.1e-117 392.5 0.0 1.1e-117 392.5 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain PIF1 PF05970.9 KFM04751.1 - 0.00069 18.6 1.1 0.1 11.5 0.0 2.4 2 0 0 2 2 2 2 PIF1-like helicase AAA_22 PF13401.1 KFM04751.1 - 1.3 9.1 0.0 1.3 9.1 0.0 2.9 2 1 1 3 3 3 0 AAA domain DUF2321 PF10083.4 KFM04751.1 - 1.6 8.1 7.5 0.18 11.2 1.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) ASXH PF13919.1 KFM04752.1 - 1.5e-49 167.2 0.7 1.5e-49 167.2 0.5 2.6 3 0 0 3 3 3 1 Asx homology domain PHD_3 PF13922.1 KFM04752.1 - 4.7e-26 90.8 8.9 4.7e-26 90.8 6.2 3.6 2 0 0 2 2 2 1 PHD domain of transcriptional enhancer, Asx HARE-HTH PF05066.8 KFM04752.1 - 3.7e-15 56.0 0.0 8.8e-15 54.8 0.0 1.7 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain K_channel_TID PF07941.6 KFM04752.1 - 0.77 10.0 20.7 8.4 6.6 0.8 3.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain EF-hand_2 PF09068.6 KFM04753.1 - 2e-38 131.2 2.2 4.7e-38 130.1 1.5 1.6 1 0 0 1 1 1 1 EF hand EF-hand_3 PF09069.6 KFM04753.1 - 3.7e-36 123.0 0.1 8e-36 121.9 0.1 1.6 1 0 0 1 1 1 1 EF-hand ZZ PF00569.12 KFM04753.1 - 6.6e-10 38.3 3.0 1.7e-09 37.0 2.1 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type DUF342 PF03961.8 KFM04753.1 - 0.054 11.8 2.1 0.083 11.2 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Seryl_tRNA_N PF02403.17 KFM04753.1 - 0.057 13.4 8.9 0.12 12.3 6.2 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain EF-hand_7 PF13499.1 KFM04753.1 - 0.12 12.5 0.0 0.33 11.0 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair Mnd1 PF03962.10 KFM04753.1 - 0.22 11.1 7.3 0.49 10.0 5.0 1.6 1 0 0 1 1 1 0 Mnd1 family DUF3450 PF11932.3 KFM04753.1 - 0.44 9.7 8.9 0.72 9.0 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) APG6 PF04111.7 KFM04753.1 - 2.1 7.2 7.7 4.1 6.3 5.3 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 C1-set PF07654.10 KFM04754.1 - 0.00047 20.0 0.2 0.00088 19.2 0.1 1.5 2 0 0 2 2 2 1 Immunoglobulin C1-set domain Jnk-SapK_ap_N PF09744.4 KFM04755.1 - 3.9e-28 98.4 15.6 3.9e-28 98.4 10.8 2.9 2 1 1 3 3 3 1 JNK_SAPK-associated protein-1 RILP PF11461.3 KFM04755.1 - 0.0083 16.2 6.3 0.022 14.8 0.3 3.1 2 0 0 2 2 2 1 Rab interacting lysosomal protein Sipho_Gp157 PF05565.6 KFM04755.1 - 0.23 11.0 17.2 0.23 11.0 3.7 2.4 2 0 0 2 2 2 0 Siphovirus Gp157 IncA PF04156.9 KFM04755.1 - 0.46 10.0 21.7 0.47 10.0 2.0 2.6 2 0 0 2 2 2 0 IncA protein DUF1664 PF07889.7 KFM04755.1 - 9.7 6.0 13.5 9.4 6.0 3.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) NAD_binding_2 PF03446.10 KFM04756.1 - 8.1e-41 139.5 0.0 1.5e-40 138.6 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KFM04756.1 - 5.2e-23 81.4 1.3 9.8e-23 80.5 0.9 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase PWWP PF00855.12 KFM04756.1 - 5.5e-17 61.7 0.9 1.3e-16 60.5 0.6 1.7 1 0 0 1 1 1 1 PWWP domain F420_oxidored PF03807.12 KFM04756.1 - 6.8e-08 32.8 0.0 1.8e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 KFM04756.1 - 2.6e-05 23.4 0.0 0.00019 20.6 0.0 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KFM04756.1 - 0.00024 21.2 0.0 0.00046 20.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 KFM04756.1 - 0.00054 19.4 0.0 0.00097 18.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 KFM04756.1 - 0.0024 17.5 0.0 0.006 16.2 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KFM04756.1 - 0.043 13.5 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AT_hook PF02178.14 KFM04756.1 - 3.9 7.4 11.9 0.091 12.4 2.8 2.6 2 0 0 2 2 2 0 AT hook motif Rogdi_lz PF10259.4 KFM04757.1 - 8.4e-64 215.3 2.0 1.5e-63 214.4 1.4 1.4 1 1 0 1 1 1 1 Rogdi leucine zipper containing protein Takusan PF04822.8 KFM04757.1 - 0.14 11.9 1.0 0.31 10.8 0.7 1.6 1 0 0 1 1 1 0 Takusan 7tm_1 PF00001.16 KFM04758.1 - 8.6e-60 202.0 16.0 1e-59 201.8 11.1 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.4 KFM04758.1 - 3.7e-14 52.5 13.0 1.2e-12 47.5 9.0 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.4 KFM04758.1 - 2.7e-08 33.2 12.8 3.4e-08 32.9 8.7 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.4 KFM04758.1 - 0.0014 17.7 8.3 0.0014 17.7 5.7 2.3 1 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx Flavi_capsid PF01003.14 KFM04758.1 - 0.1 12.1 0.1 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Flavivirus capsid protein C DUF420 PF04238.7 KFM04758.1 - 2.5 8.0 14.9 0.071 13.0 1.1 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF420) Death PF00531.17 KFM04759.1 - 0.0004 20.0 0.8 0.00081 19.1 0.5 1.5 1 0 0 1 1 1 1 Death domain PH PF00169.24 KFM04760.1 - 9.3e-42 141.4 26.5 4.7e-09 36.3 0.2 7.1 7 0 0 7 7 7 6 PH domain RhoGAP PF00620.22 KFM04760.1 - 2.4e-41 140.8 0.3 1e-40 138.8 0.1 2.3 2 0 0 2 2 2 1 RhoGAP domain ArfGap PF01412.13 KFM04760.1 - 1.4e-33 115.1 1.7 1.1e-32 112.2 0.1 3.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH_11 PF15413.1 KFM04760.1 - 1.4e-11 44.6 20.5 0.00069 19.8 0.2 7.6 6 2 0 6 6 6 4 Pleckstrin homology domain SAM_2 PF07647.12 KFM04760.1 - 1.7e-10 40.6 0.1 9.7e-10 38.1 0.0 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH_6 PF15406.1 KFM04760.1 - 1.2e-09 38.2 0.5 0.00065 19.7 0.0 3.8 3 0 0 3 3 3 2 Pleckstrin homology domain PH_8 PF15409.1 KFM04760.1 - 4.5e-08 33.0 6.1 0.18 11.9 0.2 5.6 5 0 0 5 5 5 3 Pleckstrin homology domain SAM_1 PF00536.25 KFM04760.1 - 5.7e-08 32.8 0.0 1.9e-07 31.1 0.0 2.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_3 PF14593.1 KFM04760.1 - 6e-07 29.2 3.9 0.0051 16.6 0.1 4.1 4 0 0 4 4 4 2 PH domain RA PF00788.18 KFM04760.1 - 1.2e-05 25.6 0.0 9.9e-05 22.7 0.0 2.7 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain Mcp5_PH PF12814.2 KFM04760.1 - 0.00028 20.8 2.8 0.62 9.9 0.0 4.4 4 0 0 4 4 4 1 Meiotic cell cortex C-terminal pleckstrin homology DUF1030 PF06270.6 KFM04760.1 - 0.16 11.5 0.0 0.36 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1030) E_Pc_C PF06752.7 KFM04762.1 - 2.5e-97 324.9 28.8 5.1e-97 323.9 20.0 1.5 1 0 0 1 1 1 1 Enhancer of Polycomb C-terminus EPL1 PF10513.4 KFM04762.1 - 1.5e-17 64.2 1.1 1.5e-17 64.2 0.8 3.5 4 0 0 4 4 4 2 Enhancer of polycomb-like Kinesin PF00225.18 KFM04763.1 - 8.8e-111 369.8 2.7 8.8e-111 369.8 1.9 2.8 3 1 0 3 3 3 1 Kinesin motor domain Reo_sigmaC PF04582.7 KFM04763.1 - 0.0024 17.1 26.5 0.05 12.7 4.7 3.9 2 1 1 3 3 3 3 Reovirus sigma C capsid protein RhoGAP PF00620.22 KFM04764.1 - 5.3e-50 168.9 1.2 6e-50 168.8 0.0 1.6 2 0 0 2 2 2 1 RhoGAP domain SH3_9 PF14604.1 KFM04764.1 - 2.3e-10 39.8 0.6 5.1e-10 38.7 0.4 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 KFM04764.1 - 4e-07 30.1 0.5 1.5e-06 28.3 0.3 2.0 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 KFM04764.1 - 9.5e-07 28.9 0.3 2.7e-06 27.5 0.2 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain SH3_1 PF00018.23 KFM04764.1 - 2.1e-06 26.9 3.4 6.3e-06 25.4 0.8 2.5 2 0 0 2 2 2 1 SH3 domain WW PF00397.21 KFM04764.1 - 0.00022 21.0 4.8 0.00022 21.0 3.3 4.2 3 1 1 4 4 4 2 WW domain zf-H2C2_2 PF13465.1 KFM04765.1 - 7.7e-34 114.3 55.6 1.1e-08 34.9 1.6 7.8 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2 PF00096.21 KFM04765.1 - 5.7e-23 79.8 70.1 0.0003 20.9 3.4 7.7 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM04765.1 - 6.5e-17 60.5 54.5 0.0016 18.6 1.0 7.5 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM04765.1 - 1.8e-11 43.8 55.5 0.0015 18.6 0.9 7.8 8 0 0 8 8 8 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM04765.1 - 7.6e-09 35.4 45.8 0.025 14.7 0.9 6.8 6 0 0 6 6 6 5 Zinc-finger of C2H2 type zf-Di19 PF05605.7 KFM04765.1 - 9.6e-09 35.2 25.2 3.9e-07 30.1 1.0 3.8 3 0 0 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding Homeobox PF00046.24 KFM04765.1 - 1.6e-05 24.4 0.0 4.2e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Homeobox domain zf-C2H2_6 PF13912.1 KFM04765.1 - 0.00012 21.8 57.6 0.052 13.4 0.5 7.7 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KFM04765.1 - 0.34 11.0 45.0 0.056 13.5 0.7 7.0 3 2 4 7 7 7 0 C2H2 type zinc-finger (2 copies) DUF1610 PF07754.6 KFM04765.1 - 2.9 8.0 11.4 5.8 7.1 0.2 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) zf-H2C2_2 PF13465.1 KFM04767.1 - 1.9e-07 31.0 33.1 0.00013 22.0 2.0 5.3 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFM04767.1 - 0.017 15.4 4.0 0.017 15.4 2.8 5.2 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM04767.1 - 0.027 14.7 50.1 0.68 10.4 1.6 5.9 6 0 0 6 6 6 0 C2H2-type zinc finger Gelsolin PF00626.17 KFM04768.1 - 5.3e-21 74.0 1.0 3.1e-06 26.7 0.0 5.7 5 0 0 5 5 5 4 Gelsolin repeat VHP PF02209.14 KFM04768.1 - 3.3e-15 55.4 0.1 3.3e-15 55.4 0.1 2.1 2 0 0 2 2 2 1 Villin headpiece domain JCAD PF15351.1 KFM04769.1 - 0 1871.9 61.6 0 1871.7 42.7 1.0 1 0 0 1 1 1 1 Junctional protein associated with coronary artery disease Pkinase PF00069.20 KFM04770.1 - 1.5e-52 178.3 0.0 2.3e-52 177.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM04770.1 - 2.4e-25 89.1 0.0 5.7e-25 87.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KFM04770.1 - 0.033 13.9 0.1 0.12 12.0 0.0 1.9 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KFM04770.1 - 0.082 11.8 0.0 11 4.8 0.0 2.2 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.17 KFM04770.1 - 0.13 11.6 0.2 0.34 10.2 0.0 1.7 1 1 1 2 2 2 0 RIO1 family Lys PF00062.15 KFM04771.1 - 6.2e-40 136.0 0.7 7e-40 135.8 0.5 1.0 1 0 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family SLT PF01464.15 KFM04771.1 - 0.00072 19.0 0.0 0.0009 18.7 0.0 1.1 1 0 0 1 1 1 1 Transglycosylase SLT domain Destabilase PF05497.7 KFM04771.1 - 0.0096 16.0 1.9 0.015 15.4 1.3 1.2 1 0 0 1 1 1 1 Destabilase BAMBI PF06211.7 KFM04773.1 - 3.4e-46 155.6 11.5 3.4e-46 155.6 8.0 1.7 2 0 0 2 2 2 1 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain Activin_recp PF01064.18 KFM04773.1 - 6.7e-05 23.4 11.4 6.7e-05 23.4 7.9 2.0 2 0 0 2 2 2 1 Activin types I and II receptor domain DUF1049 PF06305.6 KFM04773.1 - 0.13 11.7 1.0 0.24 10.9 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) YajC PF02699.10 KFM04773.1 - 0.16 11.6 0.2 0.3 10.7 0.1 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit KASH PF10541.4 KFM04773.1 - 0.57 10.0 6.9 5.8 6.8 0.5 2.5 2 0 0 2 2 2 0 Nuclear envelope localisation domain WW PF00397.21 KFM04774.1 - 8.8e-10 38.2 0.9 1.6e-09 37.4 0.6 1.5 1 0 0 1 1 1 1 WW domain DUF2968 PF11180.3 KFM04775.1 - 0.00024 20.5 3.7 0.00028 20.3 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) Filament PF00038.16 KFM04775.1 - 0.00047 19.7 6.0 0.00054 19.5 4.1 1.1 1 0 0 1 1 1 1 Intermediate filament protein Myosin_tail_1 PF01576.14 KFM04775.1 - 0.001 16.9 6.3 0.001 16.9 4.4 1.0 1 0 0 1 1 1 1 Myosin tail Tropomyosin PF00261.15 KFM04775.1 - 0.0023 17.0 5.5 0.0027 16.8 3.8 1.1 1 0 0 1 1 1 1 Tropomyosin ADIP PF11559.3 KFM04775.1 - 0.0039 17.1 7.4 0.0047 16.8 5.1 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding GAS PF13851.1 KFM04775.1 - 0.0046 16.1 11.4 0.22 10.6 3.5 1.9 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding DUF869 PF05911.6 KFM04775.1 - 0.0053 15.0 10.6 0.0064 14.7 7.3 1.0 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) DivIVA PF05103.8 KFM04775.1 - 0.0061 16.6 6.5 0.0076 16.3 4.5 1.2 1 0 0 1 1 1 1 DivIVA protein Seryl_tRNA_N PF02403.17 KFM04775.1 - 0.0082 16.1 7.7 0.047 13.7 0.2 2.1 1 1 1 2 2 2 2 Seryl-tRNA synthetase N-terminal domain Bacillus_HBL PF05791.6 KFM04775.1 - 0.01 15.2 3.8 0.014 14.7 2.6 1.4 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) APG6 PF04111.7 KFM04775.1 - 0.01 14.9 8.1 0.011 14.7 5.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Tropomyosin_1 PF12718.2 KFM04775.1 - 0.012 15.5 6.6 0.013 15.3 4.5 1.1 1 0 0 1 1 1 0 Tropomyosin like ERM PF00769.14 KFM04775.1 - 0.013 15.0 4.8 0.015 14.8 3.4 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family YlqD PF11068.3 KFM04775.1 - 0.013 15.5 4.9 0.016 15.2 3.4 1.2 1 0 0 1 1 1 0 YlqD protein DUF972 PF06156.8 KFM04775.1 - 0.022 15.0 7.2 0.041 14.2 5.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF3086 PF11285.3 KFM04775.1 - 0.026 13.3 0.9 0.029 13.1 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) DUF4047 PF13256.1 KFM04775.1 - 0.026 14.4 5.0 0.033 14.1 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) Herpes_UL6 PF01763.11 KFM04775.1 - 0.027 12.6 3.5 0.031 12.4 2.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF4559 PF15112.1 KFM04775.1 - 0.029 13.5 6.4 0.034 13.3 4.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) AAA_13 PF13166.1 KFM04775.1 - 0.033 12.6 3.6 0.034 12.6 2.5 1.1 1 0 0 1 1 1 0 AAA domain DUF3393 PF11873.3 KFM04775.1 - 0.042 13.3 0.7 0.049 13.1 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3393) Rootletin PF15035.1 KFM04775.1 - 0.049 13.5 7.5 0.059 13.3 5.2 1.3 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion ArsC PF03960.10 KFM04775.1 - 0.057 13.4 2.4 0.1 12.6 0.1 2.2 1 1 2 3 3 3 0 ArsC family Prefoldin_3 PF13758.1 KFM04775.1 - 0.08 12.7 1.9 0.12 12.1 1.3 1.4 1 1 0 1 1 1 0 Prefoldin subunit SlyX PF04102.7 KFM04775.1 - 0.09 13.1 6.4 0.12 12.7 3.5 1.9 1 1 1 2 2 2 0 SlyX DUF4140 PF13600.1 KFM04775.1 - 0.1 13.0 0.8 0.1 13.0 0.6 1.6 2 0 0 2 2 1 0 N-terminal domain of unknown function (DUF4140) OmpH PF03938.9 KFM04775.1 - 0.12 12.3 4.3 0.14 12.0 3.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FHIPEP PF00771.15 KFM04775.1 - 0.14 10.4 1.5 0.15 10.3 1.0 1.0 1 0 0 1 1 1 0 FHIPEP family Spc7 PF08317.6 KFM04775.1 - 0.14 10.7 11.5 0.59 8.7 3.4 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein V_ATPase_I PF01496.14 KFM04775.1 - 0.18 9.6 3.4 0.18 9.6 2.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Striatin PF08232.7 KFM04775.1 - 0.2 11.9 6.1 0.25 11.6 4.2 1.1 1 0 0 1 1 1 0 Striatin family ALMT PF11744.3 KFM04775.1 - 0.21 10.2 1.7 0.21 10.1 1.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2205 PF10224.4 KFM04775.1 - 0.21 11.2 4.6 0.45 10.1 3.1 1.7 1 1 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) DUF4200 PF13863.1 KFM04775.1 - 0.23 11.3 9.3 0.25 11.2 5.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Kinetocho_Slk19 PF12709.2 KFM04775.1 - 0.27 11.3 7.4 5.5 7.1 3.8 2.6 1 1 1 2 2 2 0 Central kinetochore-associated Sec2p PF06428.6 KFM04775.1 - 0.27 11.0 9.5 0.48 10.3 6.6 1.4 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p CENP-F_leu_zip PF10473.4 KFM04775.1 - 0.31 10.8 13.5 0.54 10.1 9.4 1.4 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF948 PF06103.6 KFM04775.1 - 0.35 10.7 4.0 1.2 9.0 1.6 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Rho_Binding PF08912.6 KFM04775.1 - 0.45 10.8 9.8 0.38 11.0 4.1 2.2 1 1 1 2 2 2 0 Rho Binding H-kinase_dim PF02895.9 KFM04775.1 - 0.46 10.8 2.5 1.3 9.4 1.8 1.8 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain Baculo_PEP_C PF04513.7 KFM04775.1 - 0.48 10.2 3.5 0.78 9.5 2.4 1.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus TBPIP PF07106.8 KFM04775.1 - 0.5 9.8 9.9 0.81 9.2 6.9 1.4 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Cortex-I_coil PF09304.5 KFM04775.1 - 0.52 10.3 9.2 0.63 10.1 6.2 1.3 1 1 0 1 1 1 0 Cortexillin I, coiled coil IncA PF04156.9 KFM04775.1 - 0.56 9.7 12.6 0.73 9.3 8.7 1.3 1 1 0 1 1 1 0 IncA protein bZIP_Maf PF03131.12 KFM04775.1 - 0.69 10.2 6.0 1 9.6 3.8 1.7 1 1 0 1 1 1 0 bZIP Maf transcription factor DUF3647 PF12363.3 KFM04775.1 - 0.7 10.0 5.1 1.4 9.0 2.6 1.9 1 1 1 2 2 2 0 Phage protein DUF4600 PF15372.1 KFM04775.1 - 0.74 10.0 8.4 0.94 9.6 2.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) Med9 PF07544.8 KFM04775.1 - 0.76 9.5 8.6 0.92 9.2 4.1 2.1 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 UPF0242 PF06785.6 KFM04775.1 - 0.81 8.3 7.6 0.9 8.1 5.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) HR1 PF02185.11 KFM04775.1 - 0.86 9.3 9.1 0.37 10.5 4.4 1.9 1 1 1 2 2 2 0 Hr1 repeat DUF342 PF03961.8 KFM04775.1 - 0.9 7.8 6.7 0.95 7.8 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TMF_DNA_bd PF12329.3 KFM04775.1 - 0.99 9.2 12.4 1.2e+02 2.5 8.7 2.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Enkurin PF13864.1 KFM04775.1 - 1.2 9.3 7.6 1.5 9.0 4.7 1.6 1 1 0 1 1 1 0 Calmodulin-binding DUF904 PF06005.7 KFM04775.1 - 1.4 9.2 13.7 9.1 6.6 9.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF904) TPX2 PF06886.6 KFM04775.1 - 1.5 8.9 6.5 29 4.8 2.9 2.2 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) AATF-Che1 PF13339.1 KFM04775.1 - 1.6 8.8 7.0 3.5 7.7 4.3 1.7 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Med2 PF11214.3 KFM04775.1 - 4.1 7.4 9.0 7.1 6.7 0.1 2.2 1 1 1 2 2 2 0 Mediator complex subunit 2 DivIC PF04977.10 KFM04775.1 - 6.3 6.3 10.4 12 5.5 6.0 2.3 1 1 1 2 2 2 0 Septum formation initiator Spc24 PF08286.6 KFM04775.1 - 7.5 6.2 8.4 16 5.1 5.8 1.8 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Guanylate_kin PF00625.16 KFM04776.1 - 5.1e-50 169.4 0.4 1.5e-48 164.6 0.2 2.2 1 1 0 1 1 1 1 Guanylate kinase L27 PF02828.11 KFM04776.1 - 1.6e-21 75.7 3.1 2.3e-10 39.9 0.1 2.6 2 0 0 2 2 2 2 L27 domain PDZ PF00595.19 KFM04776.1 - 2.1e-13 50.2 0.8 5e-13 49.0 0.6 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) SH3_2 PF07653.12 KFM04776.1 - 1.5e-07 30.8 0.0 3.6e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM04776.1 - 1.5e-07 30.6 0.4 1.5e-06 27.4 0.2 2.6 2 1 0 2 2 2 1 SH3 domain PDZ_2 PF13180.1 KFM04776.1 - 3.1e-05 23.7 0.1 0.00011 21.9 0.1 2.0 1 0 0 1 1 1 1 PDZ domain SH3_9 PF14604.1 KFM04776.1 - 0.00024 20.6 0.0 0.00056 19.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Tricorn_PDZ PF14685.1 KFM04776.1 - 0.062 13.1 0.0 0.42 10.4 0.0 2.3 2 1 0 2 2 2 0 Tricorn protease PDZ domain Arm PF00514.18 KFM04777.1 - 2.4e-56 185.7 24.2 0.00071 19.3 0.0 13.6 13 0 0 13 13 13 13 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFM04777.1 - 5.1e-26 90.7 4.0 1.3e-08 35.0 0.1 6.8 4 2 1 5 5 5 5 HEAT repeats HEAT PF02985.17 KFM04777.1 - 1e-09 37.6 14.4 0.023 14.7 0.1 7.6 8 0 0 8 8 8 3 HEAT repeat Arm_2 PF04826.8 KFM04777.1 - 4.7e-09 35.7 3.0 4.7 6.2 0.0 7.0 3 2 4 7 7 7 3 Armadillo-like Adaptin_N PF01602.15 KFM04777.1 - 2.3e-08 32.8 0.0 0.00027 19.3 0.1 3.5 1 1 1 3 3 3 2 Adaptin N terminal region HEAT_EZ PF13513.1 KFM04777.1 - 4.9e-08 33.2 7.3 0.079 13.4 0.1 8.0 8 1 1 9 9 9 2 HEAT-like repeat KAP PF05804.7 KFM04777.1 - 3.3e-05 22.0 0.0 0.05 11.5 0.0 3.1 3 0 0 3 3 3 2 Kinesin-associated protein (KAP) Proteasom_PSMB PF10508.4 KFM04777.1 - 4e-05 22.0 2.2 0.0031 15.8 0.0 3.2 3 0 0 3 3 3 1 Proteasome non-ATPase 26S subunit WAPL PF07814.8 KFM04777.1 - 0.0016 17.1 2.2 0.15 10.7 0.0 4.0 3 2 1 4 4 4 1 Wings apart-like protein regulation of heterochromatin Homeobox_KN PF05920.6 KFM04778.1 - 7.2e-15 54.4 0.2 1.4e-14 53.4 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KFM04778.1 - 2e-05 24.1 0.2 4.7e-05 22.9 0.2 1.6 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 KFM04778.1 - 0.067 12.2 0.3 0.17 10.9 0.0 1.7 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Period_C PF12114.3 KFM04778.1 - 0.12 12.0 3.3 0.22 11.1 2.3 1.4 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Ras PF00071.17 KFM04779.1 - 3.8e-51 172.6 0.1 4.4e-51 172.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Arf PF00025.16 KFM04779.1 - 1.3e-12 47.3 0.1 1.5e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 KFM04779.1 - 1.7e-12 47.8 0.0 2.3e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KFM04779.1 - 0.00012 21.5 0.0 0.0002 20.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFM04779.1 - 0.016 14.3 0.0 0.02 14.0 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 KFM04779.1 - 0.067 12.7 0.0 0.085 12.3 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Patched PF02460.13 KFM04780.1 - 1.3e-162 542.6 23.7 1.5e-162 542.4 16.4 1.0 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 KFM04780.1 - 1.2e-43 148.1 5.5 1.2e-43 148.1 3.8 2.5 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 KFM04780.1 - 0.00064 18.5 3.7 0.00064 18.5 2.6 2.4 2 0 0 2 2 2 1 MMPL family Peptidase_M41 PF01434.13 KFM04781.1 - 5.8e-75 251.4 2.7 1e-74 250.6 1.9 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KFM04781.1 - 2e-41 141.2 0.0 6.1e-41 139.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFM04781.1 - 5.4e-05 23.3 0.0 0.0029 17.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KFM04781.1 - 9.2e-05 22.1 0.0 0.00052 19.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KFM04781.1 - 9.7e-05 22.4 0.1 0.0033 17.4 0.1 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KFM04781.1 - 0.00024 21.8 0.0 0.0016 19.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 KFM04781.1 - 0.00029 19.7 0.2 0.00073 18.3 0.0 1.8 2 0 0 2 2 2 1 TIP49 C-terminus RuvB_N PF05496.7 KFM04781.1 - 0.0003 19.9 0.0 0.00077 18.5 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 KFM04781.1 - 0.0014 18.0 0.0 0.0044 16.4 0.0 1.9 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 KFM04781.1 - 0.0022 17.7 0.2 0.0057 16.3 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 KFM04781.1 - 0.0025 17.2 0.3 0.048 13.0 0.2 2.3 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KFM04781.1 - 0.0053 15.8 0.0 0.012 14.6 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 KFM04781.1 - 0.0057 16.5 0.0 0.016 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KFM04781.1 - 0.01 15.0 0.3 0.031 13.4 0.2 1.8 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 KFM04781.1 - 0.014 15.6 0.0 0.054 13.8 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_2 PF07724.9 KFM04781.1 - 0.015 15.2 0.0 0.042 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KFM04781.1 - 0.019 13.8 0.0 0.047 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 KFM04781.1 - 0.029 14.2 0.0 0.091 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KFM04781.1 - 0.043 13.7 0.2 0.11 12.4 0.0 1.8 2 0 0 2 2 1 0 AAA domain PhoH PF02562.11 KFM04781.1 - 0.11 11.6 0.5 0.33 10.1 0.1 1.9 2 0 0 2 2 2 0 PhoH-like protein FumaraseC_C PF10415.4 KFM04781.1 - 0.63 10.1 4.6 1.9 8.6 1.0 3.2 3 0 0 3 3 3 0 Fumarase C C-terminus Pkinase PF00069.20 KFM04782.1 - 8.6e-59 198.7 0.0 6.7e-38 130.3 0.2 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFM04782.1 - 1.5e-30 106.1 0.0 1.1e-23 83.6 0.3 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KFM04782.1 - 0.00027 20.7 0.1 0.0053 16.5 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KFM04782.1 - 0.001 18.0 0.0 0.0085 15.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFM04782.1 - 0.02 13.9 0.0 0.045 12.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ACBP PF00887.14 KFM04783.1 - 2.6e-27 94.3 0.1 5.3e-27 93.3 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein Abi_HHR PF07815.9 KFM04784.1 - 2.5e-34 117.2 0.4 5.1e-34 116.2 0.3 1.5 1 0 0 1 1 1 1 Abl-interactor HHR SH3_1 PF00018.23 KFM04784.1 - 1.4e-09 37.1 0.7 2.3e-09 36.5 0.5 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFM04784.1 - 1.6e-06 27.5 0.2 3.4e-06 26.5 0.1 1.6 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KFM04784.1 - 0.076 12.5 0.1 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain polyprenyl_synt PF00348.12 KFM04785.1 - 1.4e-53 181.3 0.1 1.8e-53 181.0 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.6 KFM04785.1 - 0.00069 19.1 0.2 0.0012 18.3 0.1 1.3 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 UPF0061 PF02696.9 KFM04786.1 - 2.4e-81 273.5 0.0 3e-81 273.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family dTDP_sugar_isom PF00908.12 KFM04786.1 - 0.063 12.6 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 dTDP-4-dehydrorhamnose 3,5-epimerase RA PF00788.18 KFM04787.1 - 4.3e-13 49.5 2.0 3e-12 46.8 0.5 2.4 1 1 1 2 2 2 1 Ras association (RalGDS/AF-6) domain PH PF00169.24 KFM04787.1 - 9.8e-12 44.9 0.2 3.5e-11 43.2 0.1 2.0 2 0 0 2 2 2 1 PH domain TNFR_c6 PF00020.13 KFM04788.1 - 3.8e-06 26.8 9.9 8.7e-06 25.7 6.9 1.7 1 0 0 1 1 1 1 TNFR/NGFR cysteine-rich region EGF_CA PF07645.10 KFM04788.1 - 0.0069 16.3 0.2 0.0069 16.3 0.1 2.7 2 1 0 2 2 2 1 Calcium-binding EGF domain cEGF PF12662.2 KFM04788.1 - 0.066 12.8 3.1 0.15 11.7 2.1 1.7 1 0 0 1 1 1 0 Complement Clr-like EGF-like Pyridoxal_deC PF00282.14 KFM04789.1 - 3.6e-131 437.0 0.0 4.2e-131 436.7 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KFM04789.1 - 0.0001 21.1 0.0 0.0022 16.8 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KFM04789.1 - 0.00027 20.1 0.0 0.00036 19.7 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Myosin_head PF00063.16 KFM04790.1 - 9.4e-201 668.4 5.1 2e-200 667.3 3.5 1.6 1 0 0 1 1 1 1 Myosin head (motor domain) Pkinase PF00069.20 KFM04790.1 - 2e-63 213.9 0.0 4.7e-63 212.7 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM04790.1 - 3.6e-44 150.7 0.0 7.3e-44 149.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase IQ PF00612.22 KFM04790.1 - 5e-24 81.5 15.8 1.7e-05 23.9 0.1 5.8 5 0 0 5 5 5 5 IQ calmodulin-binding motif Kinase-like PF14531.1 KFM04790.1 - 4.8e-05 22.4 0.0 0.00011 21.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFM04790.1 - 0.00065 19.5 0.0 0.51 10.0 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family AAA_22 PF13401.1 KFM04790.1 - 0.0022 18.1 0.0 0.012 15.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain 7tm_3 PF00003.17 KFM04791.1 - 1.8e-20 73.2 20.7 3.1e-20 72.5 14.3 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR SKI PF01202.17 KFM04792.1 - 7.6e-33 113.6 0.0 1.5e-32 112.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase Thr_synth_N PF14821.1 KFM04792.1 - 6e-14 51.8 0.0 1.7e-13 50.3 0.0 1.9 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 KFM04792.1 - 1.7e-11 43.8 0.0 3.1e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AAA_17 PF13207.1 KFM04792.1 - 1.8e-09 38.4 0.0 6.3e-09 36.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KFM04792.1 - 4.1e-05 23.7 0.0 0.00038 20.6 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 KFM04792.1 - 7.7e-05 21.9 0.1 0.00018 20.7 0.1 1.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 KFM04792.1 - 8.3e-05 22.9 0.0 0.0003 21.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFM04792.1 - 0.0014 18.5 0.0 0.0078 16.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KFM04792.1 - 0.005 15.9 0.0 0.0095 15.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 KFM04792.1 - 0.0051 15.9 0.0 0.01 14.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Acid_PPase PF12689.2 KFM04792.1 - 0.037 13.6 0.0 0.098 12.2 0.0 1.6 1 0 0 1 1 1 0 Acid Phosphatase AAA_22 PF13401.1 KFM04792.1 - 0.051 13.7 0.0 0.25 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 KFM04792.1 - 0.074 12.4 0.1 0.17 11.2 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.1 KFM04792.1 - 0.083 12.6 0.9 0.22 11.2 0.1 2.1 2 0 0 2 2 2 0 Part of AAA domain ADK PF00406.17 KFM04792.1 - 0.15 11.9 0.1 6.6 6.5 0.0 2.4 2 0 0 2 2 2 0 Adenylate kinase AAA_24 PF13479.1 KFM04792.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Enkurin PF13864.1 KFM04793.1 - 1.3e-24 86.1 9.9 1.3e-24 86.1 6.9 2.7 3 0 0 3 3 3 1 Calmodulin-binding TelA PF05816.6 KFM04793.1 - 0.019 13.6 2.7 0.028 13.1 1.9 1.2 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) V-SNARE PF05008.10 KFM04793.1 - 0.099 12.8 5.2 0.094 12.8 2.1 2.1 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Pribosyltran PF00156.22 KFM04794.1 - 8.1e-07 28.8 0.0 0.024 14.3 0.0 2.2 2 0 0 2 2 2 2 Phosphoribosyl transferase domain RhoGAP PF00620.22 KFM04795.1 - 2.2e-50 170.1 0.0 4.4e-50 169.2 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 KFM04795.1 - 1.9e-15 56.9 3.8 2e-13 50.4 0.1 3.2 2 0 0 2 2 2 2 PH domain PH_9 PF15410.1 KFM04795.1 - 2.3e-14 53.5 0.0 7.4e-14 51.9 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PDZ PF00595.19 KFM04795.1 - 1.5e-10 41.0 0.1 4.7e-10 39.5 0.1 1.8 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM04795.1 - 6e-07 29.2 0.1 2.7e-06 27.1 0.0 2.1 2 0 0 2 2 2 1 PDZ domain PH_11 PF15413.1 KFM04795.1 - 0.01 16.0 0.1 0.053 13.7 0.1 2.4 1 0 0 1 1 1 0 Pleckstrin homology domain OTU PF02338.14 KFM04797.1 - 2.7e-21 76.3 0.0 4.1e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 KFM04797.1 - 0.0044 16.4 0.1 0.11 11.7 0.1 2.3 1 1 1 2 2 2 1 Peptidase C65 Otubain SelR PF01641.13 KFM04798.1 - 8.1e-29 99.8 0.2 1e-28 99.4 0.1 1.2 1 0 0 1 1 1 1 SelR domain HNH_5 PF14279.1 KFM04798.1 - 0.01 15.8 0.2 0.012 15.5 0.1 1.3 1 0 0 1 1 1 0 HNH endonuclease Yippee-Mis18 PF03226.9 KFM04798.1 - 0.02 14.9 0.0 0.022 14.8 0.0 1.1 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2296 PF10058.4 KFM04798.1 - 0.023 14.4 0.1 0.027 14.1 0.1 1.4 1 1 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) DUF281 PF03436.8 KFM04798.1 - 0.037 14.0 0.4 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF281) DZR PF12773.2 KFM04798.1 - 0.05 13.4 0.7 0.16 11.8 0.5 1.8 1 1 0 1 1 1 0 Double zinc ribbon DUF4182 PF13790.1 KFM04798.1 - 0.078 12.7 0.5 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4182) Arm PF00514.18 KFM04799.1 - 6.7e-52 171.6 24.7 1.4e-08 34.2 0.0 11.8 12 0 0 12 12 12 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFM04799.1 - 2.7e-35 120.4 13.3 6.8e-07 29.4 0.0 6.5 1 1 6 8 8 8 8 HEAT repeats EDR1 PF14381.1 KFM04799.1 - 1.4e-29 103.1 0.0 7.8e-25 87.6 0.0 3.3 3 0 0 3 3 3 2 Ethylene-responsive protein kinase Le-CTR1 HEAT PF02985.17 KFM04799.1 - 7.2e-27 91.0 14.1 0.0013 18.6 0.1 9.8 10 0 0 10 10 9 7 HEAT repeat HEAT_EZ PF13513.1 KFM04799.1 - 6.4e-16 58.3 9.3 0.064 13.7 0.0 9.3 8 1 2 10 10 10 4 HEAT-like repeat Adaptin_N PF01602.15 KFM04799.1 - 8.9e-13 47.3 11.8 2.7e-08 32.5 4.8 3.7 1 1 2 3 3 3 3 Adaptin N terminal region V-ATPase_H_C PF11698.3 KFM04799.1 - 8.6e-10 38.5 4.4 0.06 13.2 0.0 5.9 2 2 4 7 7 7 3 V-ATPase subunit H V-ATPase_H_N PF03224.9 KFM04799.1 - 4.8e-08 32.4 0.8 0.014 14.4 0.1 3.5 1 1 2 3 3 3 2 V-ATPase subunit H Arm_2 PF04826.8 KFM04799.1 - 7e-08 31.8 12.1 0.18 10.8 0.1 6.1 1 1 6 7 7 7 4 Armadillo-like Proteasom_PSMB PF10508.4 KFM04799.1 - 2.8e-07 29.1 10.0 3.6e-05 22.2 4.0 3.1 1 1 1 3 3 3 2 Proteasome non-ATPase 26S subunit CLASP_N PF12348.3 KFM04799.1 - 3.8e-06 26.4 1.6 0.61 9.3 0.1 3.8 2 1 2 4 4 4 3 CLASP N terminal Cnd1 PF12717.2 KFM04799.1 - 7.2e-06 25.9 1.6 0.71 9.7 0.0 5.1 2 1 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 KFM04799.1 - 0.048 13.5 2.2 19 5.2 0.0 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2435) Polysacc_syn_2C PF08485.5 KFM04799.1 - 0.11 12.0 0.2 0.55 9.7 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein C-terminal DUF3361 PF11841.3 KFM04799.1 - 0.94 9.1 7.0 8.9 5.9 0.1 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF3361) PIP5K PF01504.13 KFM04800.1 - 6.9e-73 244.8 0.1 8.6e-73 244.5 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Arm PF00514.18 KFM04801.1 - 2.5e-40 134.9 20.4 7.2e-09 35.1 0.0 9.3 9 0 0 9 9 9 6 Armadillo/beta-catenin-like repeat HEAT PF02985.17 KFM04801.1 - 7.3e-17 59.8 12.6 0.058 13.4 0.1 8.4 9 0 0 9 9 9 5 HEAT repeat HEAT_2 PF13646.1 KFM04801.1 - 1.8e-16 60.1 13.1 1e-05 25.6 0.8 5.2 1 1 4 6 6 6 6 HEAT repeats HEAT_EZ PF13513.1 KFM04801.1 - 4.2e-13 49.3 15.1 0.0034 17.8 0.0 6.4 3 2 5 8 8 7 5 HEAT-like repeat DNA_alkylation PF08713.6 KFM04801.1 - 9.5e-09 35.0 0.0 0.6 9.5 0.0 4.3 2 1 1 4 4 4 3 DNA alkylation repair enzyme Adaptin_N PF01602.15 KFM04801.1 - 3.1e-07 29.1 3.4 0.0073 14.6 1.7 3.7 1 1 2 3 3 3 3 Adaptin N terminal region Proteasom_PSMB PF10508.4 KFM04801.1 - 1.2e-06 27.1 1.5 0.00029 19.2 0.2 3.2 1 1 2 3 3 3 1 Proteasome non-ATPase 26S subunit Cnd1 PF12717.2 KFM04801.1 - 2e-06 27.7 0.6 0.21 11.4 0.1 4.4 3 1 1 5 5 4 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 KFM04801.1 - 1.2e-05 24.8 0.3 0.16 11.3 0.0 3.9 3 2 1 4 4 4 1 CLASP N terminal Atx10homo_assoc PF09759.4 KFM04801.1 - 0.00011 21.9 0.1 1.6 8.5 0.0 4.1 4 1 1 5 5 5 2 Spinocerebellar ataxia type 10 protein domain XPC-binding PF09280.6 KFM04801.1 - 0.016 14.6 0.5 19 4.8 0.0 4.1 4 0 0 4 4 4 0 XPC-binding domain HEAT_PBS PF03130.11 KFM04801.1 - 0.022 15.1 11.1 0.73 10.4 0.3 5.9 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat DUF3731 PF12531.3 KFM04801.1 - 0.044 13.2 1.4 4.1 6.8 0.3 2.8 2 1 1 3 3 3 0 DNA-K related protein DUF2336 PF10098.4 KFM04801.1 - 0.17 11.1 7.7 0.1 11.8 0.3 3.1 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2336) zf-RING_2 PF13639.1 KFM04802.1 - 0.034 13.9 2.1 0.067 13.0 1.5 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 KFM04802.1 - 0.04 13.9 4.8 0.088 12.8 3.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4467 PF14729.1 KFM04802.1 - 0.04 14.2 0.1 0.074 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function with cystatin-like fold (DUF4467) zf-C3HC4_3 PF13920.1 KFM04802.1 - 0.078 12.6 2.7 0.14 11.8 1.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM04802.1 - 0.58 9.8 4.9 1.3 8.7 3.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HCaRG PF07258.9 KFM04803.1 - 1.1e-17 64.0 0.0 1.2e-17 63.9 0.0 1.0 1 0 0 1 1 1 1 HCaRG protein DUF842 PF05811.8 KFM04803.1 - 0.067 12.6 1.3 0.082 12.3 0.9 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) DnaJ PF00226.26 KFM04804.1 - 1.1e-17 63.4 0.5 2.9e-17 62.1 0.4 1.8 1 0 0 1 1 1 1 DnaJ domain Myb_DNA-binding PF00249.26 KFM04804.1 - 3.5e-12 46.1 0.9 1.1e-07 31.7 0.1 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFM04804.1 - 1.4e-07 31.4 0.1 0.02 14.9 0.2 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF4234 PF14018.1 KFM04804.1 - 0.065 12.9 0.2 0.18 11.5 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4234) zf-HC5HC2H_2 PF13832.1 KFM04805.1 - 4e-31 107.2 20.5 4.7e-31 107.0 7.9 2.5 2 0 0 2 2 2 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KFM04805.1 - 1.4e-20 73.2 10.5 1.4e-20 73.2 7.3 3.4 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.1 KFM04805.1 - 6.4e-13 47.7 4.4 6.4e-13 47.7 3.0 2.8 3 0 0 3 3 3 1 PHD-finger PHD PF00628.24 KFM04805.1 - 4.7e-07 29.3 9.9 4.7e-07 29.3 6.9 2.9 2 0 0 2 2 2 2 PHD-finger DUF4584 PF15223.1 KFM04806.1 - 1.7e-94 317.3 10.2 2.8e-94 316.6 7.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4584) Ski_Sno PF02437.12 KFM04806.1 - 6.6e-17 61.1 0.1 1.4e-16 60.1 0.1 1.5 1 0 0 1 1 1 1 SKI/SNO/DAC family Nebulin PF00880.13 KFM04807.1 - 9.7e-29 97.6 2.6 2e-10 39.7 0.1 3.3 3 0 0 3 3 3 3 Nebulin repeat SH3_9 PF14604.1 KFM04807.1 - 1.9e-16 59.3 0.0 3e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM04807.1 - 1e-13 50.4 0.0 2e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFM04807.1 - 3.5e-06 26.4 0.0 7.6e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PSI PF01437.20 KFM04808.1 - 2.4e-07 30.8 11.0 4.1e-07 30.0 7.6 1.4 1 0 0 1 1 1 1 Plexin repeat MGC-24 PF05283.6 KFM04808.1 - 0.095 12.4 10.8 0.38 10.5 7.5 1.8 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) DUF1459 PF07312.6 KFM04809.1 - 0.025 14.4 0.2 0.047 13.6 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1459) PetM PF08041.6 KFM04809.1 - 0.028 13.8 1.1 0.043 13.2 0.7 1.3 1 0 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 MAM PF00629.18 KFM04810.1 - 1.1e-23 83.7 2.2 1.3e-23 83.5 1.5 1.0 1 0 0 1 1 1 1 MAM domain MAM PF00629.18 KFM04811.1 - 9.6e-42 142.4 0.0 1.1e-41 142.3 0.0 1.0 1 0 0 1 1 1 1 MAM domain MAM PF00629.18 KFM04812.1 - 3.2e-18 66.0 0.5 3.5e-18 65.8 0.3 1.0 1 0 0 1 1 1 1 MAM domain Arf PF00025.16 KFM04814.1 - 3.6e-65 218.4 0.2 4e-65 218.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KFM04814.1 - 2.6e-14 52.9 0.1 2.9e-14 52.7 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KFM04814.1 - 5.5e-13 48.5 0.1 6.7e-13 48.2 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KFM04814.1 - 1.8e-11 44.5 0.1 2.3e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 KFM04814.1 - 9.4e-09 34.4 0.4 3e-06 26.1 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KFM04814.1 - 4.6e-08 32.4 0.1 5.4e-08 32.2 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFM04814.1 - 8.6e-08 32.1 0.1 1.2e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFM04814.1 - 0.00029 20.3 0.0 0.0051 16.2 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.1 KFM04814.1 - 0.0031 17.4 0.2 0.01 15.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 KFM04814.1 - 0.099 11.7 0.2 0.26 10.3 0.1 1.7 1 1 1 2 2 2 0 KaiC FeoB_N PF02421.13 KFM04814.1 - 0.1 11.8 0.6 0.43 9.8 0.2 1.9 1 1 1 2 2 2 0 Ferrous iron transport protein B Dynamin_N PF00350.18 KFM04814.1 - 0.15 11.8 0.2 0.86 9.3 0.1 1.9 1 1 1 2 2 2 0 Dynamin family Nol1_Nop2_Fmu PF01189.12 KFM04815.1 - 1.6e-38 132.6 0.0 4e-38 131.4 0.0 1.5 2 0 0 2 2 2 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 KFM04815.1 - 3.9e-09 36.2 0.0 7.9e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KFM04815.1 - 2.4e-08 34.1 0.0 5.8e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 KFM04815.1 - 1.8e-07 31.2 0.0 2.9e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFM04815.1 - 4.7e-07 30.3 0.0 8.2e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PUA PF01472.15 KFM04815.1 - 0.0011 18.6 0.0 0.0024 17.5 0.0 1.6 1 0 0 1 1 1 1 PUA domain Methyltransf_15 PF09445.5 KFM04815.1 - 0.0053 16.3 0.0 0.012 15.1 0.0 1.6 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.14 KFM04815.1 - 0.0071 15.9 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.7 KFM04815.1 - 0.016 15.6 0.0 0.13 12.7 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KFM04815.1 - 0.021 14.2 0.0 0.19 11.1 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.13 KFM04815.1 - 0.066 12.3 0.0 0.28 10.2 0.0 1.8 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Guanylate_kin PF00625.16 KFM04816.1 - 1.7e-49 167.7 1.1 2.1e-49 167.4 0.1 1.6 2 0 0 2 2 2 1 Guanylate kinase VGCC_beta4Aa_N PF12052.3 KFM04816.1 - 6e-24 83.6 7.8 6e-24 83.6 5.4 2.7 2 0 0 2 2 2 1 Voltage gated calcium channel subunit beta domain 4Aa N terminal SH3_1 PF00018.23 KFM04816.1 - 9.8e-05 21.6 0.1 0.00034 19.9 0.1 1.9 2 0 0 2 2 2 1 SH3 domain ImpA-rel_N PF06812.7 KFM04816.1 - 0.044 13.5 0.1 0.092 12.5 0.0 1.6 1 0 0 1 1 1 0 ImpA-related N-terminal SH3_9 PF14604.1 KFM04816.1 - 0.049 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain zf-CCCH PF00642.19 KFM04818.1 - 2.3e-14 52.6 15.7 3.1e-05 23.5 0.6 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) AF-4 PF05110.8 KFM04818.1 - 0.02 12.8 21.9 0.034 12.0 15.2 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF2217 PF10265.4 KFM04818.1 - 9.5 4.8 7.6 15 4.1 5.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Pkinase PF00069.20 KFM04819.1 - 6.6e-30 104.1 0.0 7.2e-30 103.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM04819.1 - 1.3e-13 50.5 0.0 1.4e-13 50.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM04819.1 - 0.00082 18.4 0.0 0.001 18.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Syntaxin_2 PF14523.1 KFM04820.1 - 3.8e-07 30.0 0.2 1.4e-06 28.2 0.2 1.8 2 0 0 2 2 2 1 Syntaxin-like protein DUF2493 PF10686.4 KFM04820.1 - 0.033 13.7 0.0 0.28 10.7 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2493) DUF1539 PF07560.6 KFM04820.1 - 0.037 13.8 0.1 0.076 12.8 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) DUF2155 PF09923.4 KFM04820.1 - 0.039 14.0 0.4 6.2 6.9 0.0 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2155) CRF PF00473.12 KFM04820.1 - 0.18 11.8 2.7 0.16 12.1 0.7 1.8 2 0 0 2 2 2 0 Corticotropin-releasing factor family Syndecan PF01034.15 KFM04820.1 - 0.19 11.4 2.0 0.36 10.5 1.4 1.5 1 0 0 1 1 1 0 Syndecan domain TUDOR PF00567.19 KFM04822.1 - 2.9e-12 46.4 2.5 3.6e-12 46.2 1.7 1.1 1 0 0 1 1 1 1 Tudor domain TUDOR PF00567.19 KFM04823.1 - 8.9e-09 35.2 0.1 2.1e-08 34.0 0.1 1.6 1 0 0 1 1 1 1 Tudor domain DEAD PF00270.24 KFM04823.1 - 4e-07 29.6 0.0 9.5e-07 28.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF3885 PF13021.1 KFM04823.1 - 0.071 12.8 0.0 3.5 7.4 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3885) AA_permease_2 PF13520.1 KFM04824.1 - 4e-64 216.7 45.2 4.9e-64 216.4 31.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFM04824.1 - 5e-27 94.3 41.7 6.2e-27 94.0 28.9 1.0 1 0 0 1 1 1 1 Amino acid permease AAA_26 PF13500.1 KFM04825.1 - 2.8 7.4 6.4 0.38 10.3 0.9 2.1 2 0 0 2 2 2 0 AAA domain Strep_SA_rep PF06696.6 KFM04825.1 - 3.7 7.4 10.5 15 5.5 0.0 4.3 4 0 0 4 4 4 0 Streptococcal surface antigen repeat HHH_2 PF12826.2 KFM04826.1 - 2.6e-06 27.2 0.0 5.4e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 KFM04826.1 - 0.0034 17.5 0.0 0.0065 16.6 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain 5_3_exonuc PF01367.15 KFM04826.1 - 0.031 14.4 0.0 0.057 13.6 0.0 1.4 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold HHH PF00633.18 KFM04826.1 - 0.11 12.1 0.0 3.2 7.6 0.0 2.6 3 0 0 3 3 3 0 Helix-hairpin-helix motif BRO1 PF03097.13 KFM04827.1 - 3.3e-110 368.3 0.2 4.3e-110 367.9 0.1 1.1 1 0 0 1 1 1 1 BRO1-like domain HR1 PF02185.11 KFM04827.1 - 8.1e-12 44.7 3.4 2.1e-11 43.3 2.3 1.8 1 0 0 1 1 1 1 Hr1 repeat PDZ PF00595.19 KFM04827.1 - 9.2e-06 25.7 0.0 3.1e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) DUF372 PF04036.7 KFM04827.1 - 0.068 12.6 0.0 7.4 6.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF372) DUF1604 PF07713.8 KFM04828.1 - 4.8e-36 122.4 2.4 1.2e-35 121.1 0.1 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.18 KFM04828.1 - 6.4e-08 32.2 0.1 4.2e-07 29.6 0.1 2.4 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 KFM04828.1 - 0.00022 21.0 1.1 0.0012 18.6 0.0 2.8 3 0 0 3 3 3 1 DExH-box splicing factor binding site TMEM164 PF14808.1 KFM04829.1 - 6.1e-80 268.0 5.4 6.7e-80 267.9 3.7 1.0 1 0 0 1 1 1 1 TMEM164 family AMP-binding PF00501.23 KFM04830.1 - 6.3e-99 331.1 0.0 7.7e-99 330.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFM04830.1 - 0.00012 22.9 0.0 0.0014 19.5 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain NTF2 PF02136.15 KFM04831.1 - 3.2e-29 101.6 0.5 3.8e-29 101.4 0.3 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 KFM04831.1 - 0.00038 20.2 0.1 0.00045 20.0 0.1 1.1 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 SnoaL_2 PF12680.2 KFM04831.1 - 0.051 13.9 0.0 0.067 13.5 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain IRS PF02174.12 KFM04832.1 - 1e-30 105.2 0.0 2e-30 104.3 0.0 1.5 1 0 0 1 1 1 1 PTB domain (IRS-1 type) PH PF00169.24 KFM04832.1 - 2e-10 40.8 0.8 5.4e-10 39.4 0.0 2.2 3 0 0 3 3 3 1 PH domain PH_11 PF15413.1 KFM04832.1 - 4.3e-05 23.7 0.3 0.0002 21.5 0.2 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_2 PF08458.5 KFM04832.1 - 0.17 11.8 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 Plant pleckstrin homology-like region Collagen PF01391.13 KFM04833.1 - 3.2e-162 526.2 638.8 2.3e-11 43.0 14.5 21.7 6 4 16 22 22 22 22 Collagen triple helix repeat (20 copies) C4 PF01413.14 KFM04833.1 - 1.9e-93 308.0 5.0 4.6e-50 168.3 0.9 2.1 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen Collagen PF01391.13 KFM04834.1 - 4.5e-167 541.7 621.3 4.3e-10 38.9 15.4 26.0 8 7 16 24 24 24 23 Collagen triple helix repeat (20 copies) C4 PF01413.14 KFM04834.1 - 5.5e-90 296.9 6.7 4.5e-47 158.6 0.8 2.1 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen Peptidase_C54 PF03416.14 KFM04835.1 - 2.2e-112 374.7 0.0 2.7e-112 374.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Ank PF00023.25 KFM04836.1 - 1.6e-45 150.6 4.3 1.3e-10 40.5 0.1 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 KFM04836.1 - 3.5e-40 135.1 9.7 5.5e-15 55.0 0.2 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 KFM04836.1 - 3.7e-40 136.1 5.0 1.6e-19 69.9 0.3 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFM04836.1 - 5.4e-37 125.5 5.2 2.4e-13 50.1 0.1 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM04836.1 - 1.2e-34 114.8 2.2 1.1e-07 31.4 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat AMNp_N PF10423.4 KFM04836.1 - 0.14 11.7 0.0 2 8.0 0.0 2.2 2 1 0 2 2 2 0 Bacterial AMP nucleoside phosphorylase N-terminus V-set PF07686.12 KFM04837.1 - 1.2e-19 70.2 0.5 1.2e-19 70.2 0.4 3.2 3 1 0 3 3 3 1 Immunoglobulin V-set domain Ig_3 PF13927.1 KFM04837.1 - 3.4e-15 56.2 9.4 2.8e-07 30.9 3.0 2.9 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 KFM04837.1 - 1.4e-14 53.6 0.0 1.6e-06 27.8 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM04837.1 - 1e-13 51.1 4.0 3.1e-06 27.2 0.3 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Herpes_gE PF02480.11 KFM04837.1 - 1.3e-08 33.5 0.1 0.00019 19.8 0.0 2.2 2 0 0 2 2 2 2 Alphaherpesvirus glycoprotein E ig PF00047.20 KFM04837.1 - 2.2e-08 34.1 5.6 3.7e-05 23.7 0.9 2.8 2 1 0 2 2 2 2 Immunoglobulin domain Syndecan PF01034.15 KFM04837.1 - 0.0017 17.9 0.0 0.01 15.4 0.0 2.3 2 0 0 2 2 2 1 Syndecan domain V-set_CD47 PF08204.6 KFM04837.1 - 0.0053 16.5 1.8 0.0078 15.9 0.0 2.1 3 0 0 3 3 3 1 CD47 immunoglobulin-like domain Shisa PF13908.1 KFM04837.1 - 0.018 15.2 0.1 0.032 14.4 0.1 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator TMEM154 PF15102.1 KFM04837.1 - 0.023 14.3 1.7 0.067 12.8 1.2 1.8 1 1 0 1 1 1 0 TMEM154 protein family YgbB PF02542.11 KFM04837.1 - 0.034 13.9 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 YgbB family EphA2_TM PF14575.1 KFM04837.1 - 0.036 14.4 0.1 0.073 13.4 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1191 PF06697.7 KFM04837.1 - 0.041 12.6 0.0 0.077 11.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1191) TraL PF07178.6 KFM04837.1 - 0.085 12.8 0.2 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 TraL protein C2 PF00168.25 KFM04838.1 - 1.3e-34 117.8 2.1 3.3e-18 65.3 0.0 2.2 2 0 0 2 2 2 2 C2 domain Ras PF00071.17 KFM04839.1 - 9.5e-30 103.1 0.1 1.1e-29 102.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM04839.1 - 0.006 17.0 0.0 0.012 16.1 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein CENP-M PF11111.3 KFM04839.1 - 0.01 15.0 0.0 0.014 14.6 0.0 1.1 1 0 0 1 1 1 0 Centromere protein M (CENP-M) Prefoldin PF02996.12 KFM04840.1 - 3.4e-37 126.7 0.3 5.1e-37 126.1 0.2 1.3 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 KFM04840.1 - 0.00011 21.9 4.1 0.04 13.6 0.0 2.3 2 0 0 2 2 2 2 Prefoldin subunit MRL1 PF13003.2 KFM04840.1 - 0.014 15.2 0.1 0.019 14.7 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L1 ANTH PF07651.11 KFM04841.1 - 2.9e-68 229.6 1.5 4.6e-68 228.9 1.0 1.3 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 KFM04841.1 - 1.2e-06 28.4 0.1 2.9e-06 27.1 0.1 1.7 1 0 0 1 1 1 1 ENTH domain CHDCT2 PF08074.6 KFM04841.1 - 0.079 12.6 0.7 0.15 11.8 0.5 1.4 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain T2SM PF04612.7 KFM04841.1 - 2.8 7.7 7.1 3.3 7.4 3.7 1.8 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M PH PF00169.24 KFM04842.1 - 6.4e-17 61.6 0.4 2.3e-16 59.8 0.2 2.0 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 KFM04842.1 - 5e-05 23.5 4.6 0.00036 20.7 3.2 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain Mcp5_PH PF12814.2 KFM04842.1 - 0.013 15.4 0.2 0.033 14.1 0.2 1.7 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology PH_9 PF15410.1 KFM04842.1 - 0.043 13.9 0.6 0.11 12.6 0.4 1.7 1 1 0 1 1 1 0 Pleckstrin homology domain PH_3 PF14593.1 KFM04842.1 - 0.5 10.2 2.7 3.8 7.4 1.9 2.2 1 1 0 1 1 1 0 PH domain RVT_1 PF00078.22 KFM04843.1 - 0.075 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Tox-GHH PF15636.1 KFM04844.1 - 2.5e-30 103.9 1.2 5.1e-30 102.9 0.8 1.6 1 0 0 1 1 1 1 GHH signature containing HNH/Endo VII superfamily nuclease toxin Ten_N PF06484.7 KFM04844.1 - 8.7e-23 81.0 6.8 1.4e-22 80.3 4.7 1.4 1 0 0 1 1 1 1 Teneurin Intracellular Region EGF_2 PF07974.8 KFM04844.1 - 2e-17 62.9 155.8 0.00045 20.3 8.3 9.7 8 1 1 9 9 9 7 EGF-like domain NHL PF01436.16 KFM04844.1 - 1.1e-12 47.1 0.8 0.017 15.0 0.0 7.1 6 0 0 6 6 6 3 NHL repeat hEGF PF12661.2 KFM04844.1 - 1e-05 25.2 78.7 0.0047 16.9 2.4 9.3 8 0 0 8 8 8 6 Human growth factor-like EGF RHS_repeat PF05593.9 KFM04844.1 - 4.7e-05 23.4 36.0 0.013 15.6 0.4 8.7 8 2 1 9 9 9 3 RHS Repeat RHS PF03527.9 KFM04844.1 - 0.0002 21.0 0.3 0.0083 15.8 0.0 2.8 2 0 0 2 2 2 1 RHS protein SGL PF08450.7 KFM04844.1 - 0.0011 18.4 0.3 0.7 9.2 0.0 3.8 3 0 0 3 3 3 1 SMP-30/Gluconolaconase/LRE-like region CarboxypepD_reg PF13620.1 KFM04844.1 - 0.0015 18.5 0.1 0.0053 16.7 0.0 2.0 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain SH2 PF00017.19 KFM04845.1 - 1.9e-14 53.2 0.0 2.3e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 SH2 domain STAG PF08514.6 KFM04846.1 - 2e-47 159.7 0.2 9.8e-47 157.5 0.1 2.3 1 0 0 1 1 1 1 STAG domain Phage_DsbA PF11126.3 KFM04846.1 - 0.014 15.4 0.6 9.1 6.4 0.0 3.1 2 0 0 2 2 2 0 Transcriptional regulator DsbA Lig_chan PF00060.21 KFM04847.1 - 1.2e-59 200.2 0.0 2.2e-59 199.4 0.0 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel ANF_receptor PF01094.23 KFM04847.1 - 5.9e-58 196.3 0.9 1.5e-57 194.9 0.9 1.5 2 0 0 2 2 2 1 Receptor family ligand binding region Lig_chan-Glu_bd PF10613.4 KFM04847.1 - 2.1e-26 91.6 2.1 2.3e-26 91.5 0.2 2.1 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.15 KFM04847.1 - 4.9e-26 91.3 0.0 9e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 PUA PF01472.15 KFM04850.1 - 7.3e-21 73.6 0.1 1.2e-20 72.9 0.1 1.4 1 0 0 1 1 1 1 PUA domain Cullin PF00888.17 KFM04851.1 - 8.3e-178 592.5 20.2 1.2e-177 592.0 14.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KFM04851.1 - 1.2e-27 95.5 1.0 1.2e-27 95.5 0.7 2.3 2 0 0 2 2 2 1 Cullin protein neddylation domain TrmB PF01978.14 KFM04851.1 - 0.06 13.0 0.1 9 6.0 0.0 2.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HbrB PF08539.6 KFM04851.1 - 0.11 12.3 7.5 0.018 14.8 1.0 2.7 3 0 0 3 3 3 0 HbrB-like Lamp PF01299.12 KFM04852.1 - 9.9e-107 356.5 11.8 2.9e-101 338.6 4.0 2.0 1 1 1 2 2 2 2 Lysosome-associated membrane glycoprotein (Lamp) DUF368 PF04018.8 KFM04852.1 - 0.016 14.4 0.1 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF368) Adeno_E3_CR2 PF02439.10 KFM04852.1 - 0.021 14.3 0.4 0.038 13.5 0.3 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Na_K-ATPase PF00287.13 KFM04853.1 - 2.1e-98 328.6 0.4 2.5e-98 328.4 0.2 1.0 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain FAM70 PF14967.1 KFM04854.1 - 1.9e-162 540.0 6.2 2.2e-162 539.8 4.3 1.0 1 0 0 1 1 1 1 FAM70 protein DUF4064 PF13273.1 KFM04854.1 - 0.0009 19.3 10.8 0.89 9.6 7.0 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF4064) DUF1097 PF06496.6 KFM04854.1 - 7.7 6.3 11.1 3 7.6 3.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1097) BTB PF00651.26 KFM04855.1 - 7.5e-20 70.9 0.0 1.3e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 KFM04855.1 - 4.9e-07 29.7 10.4 4.5e-05 23.5 1.2 3.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM04855.1 - 0.0015 18.7 17.0 0.11 12.9 1.2 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KFM04855.1 - 0.034 14.4 16.1 0.22 11.9 0.9 3.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-CHY PF05495.7 KFM04855.1 - 0.13 12.4 6.3 0.33 11.1 4.4 1.7 1 0 0 1 1 1 0 CHY zinc finger Zn_Tnp_IS1595 PF12760.2 KFM04855.1 - 0.23 11.2 4.5 0.55 10.0 3.2 1.7 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-C2H2_6 PF13912.1 KFM04855.1 - 0.58 10.1 11.3 13 5.8 0.4 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger PyrI_C PF02748.10 KFM04855.1 - 1.3 8.5 4.7 0.58 9.6 0.5 2.2 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain C1_4 PF07975.7 KFM04855.1 - 4.2 7.4 6.7 19 5.3 1.4 3.0 1 1 2 3 3 3 0 TFIIH C1-like domain zf-BED PF02892.10 KFM04855.1 - 5.9 6.7 16.0 16 5.3 1.3 3.5 1 1 2 3 3 3 0 BED zinc finger SynMuv_product PF06047.6 KFM04856.1 - 3.6e-53 177.7 2.3 3.6e-53 177.7 1.6 3.1 2 1 1 3 3 3 1 Ras-induced vulval development antagonist MIP-T3 PF10243.4 KFM04856.1 - 0.0011 17.6 45.6 0.0014 17.2 31.6 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CDC27 PF09507.5 KFM04856.1 - 0.52 9.4 49.7 0.02 14.1 30.3 1.5 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Macoilin PF09726.4 KFM04856.1 - 1.4 7.0 25.2 2 6.6 17.5 1.2 1 0 0 1 1 1 0 Transmembrane protein Septin PF00735.13 KFM04857.1 - 8e-96 320.3 0.6 8e-96 320.3 0.4 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KFM04857.1 - 0.0006 19.7 0.0 0.0014 18.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KFM04857.1 - 0.00093 19.2 0.6 0.035 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KFM04857.1 - 0.005 16.9 2.5 0.0095 16.0 0.0 2.5 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KFM04857.1 - 0.017 14.6 0.0 0.039 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 KFM04857.1 - 0.018 14.4 1.4 1.5 8.2 0.0 2.9 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 KFM04857.1 - 0.029 13.7 1.1 0.075 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain Miro PF08477.8 KFM04857.1 - 0.034 14.6 2.6 0.038 14.4 0.1 2.5 2 1 0 2 2 2 0 Miro-like protein IMD PF08397.6 KFM04857.1 - 0.039 13.2 14.3 0.08 12.2 9.9 1.4 1 0 0 1 1 1 0 IRSp53/MIM homology domain DUF4478 PF14793.1 KFM04857.1 - 0.048 13.2 0.5 0.23 11.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4478) FtsK_SpoIIIE PF01580.13 KFM04857.1 - 0.059 12.8 2.3 0.91 8.9 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.12 KFM04857.1 - 0.087 12.6 5.0 2.2 8.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 Fzo_mitofusin PF04799.8 KFM04857.1 - 0.1 11.9 7.4 0.26 10.6 5.1 1.6 1 0 0 1 1 1 0 fzo-like conserved region AAA_11 PF13086.1 KFM04857.1 - 0.13 11.7 4.2 0.21 11.1 2.9 1.4 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 KFM04857.1 - 0.39 10.3 11.3 0.67 9.5 7.8 1.3 1 0 0 1 1 1 0 IncA protein ABC_tran PF00005.22 KFM04857.1 - 2 8.7 5.7 0.34 11.2 0.1 2.3 2 2 0 2 2 2 0 ABC transporter Atg14 PF10186.4 KFM04857.1 - 8.7 5.1 12.2 13 4.5 8.4 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 G-patch PF01585.18 KFM04858.1 - 3.9e-15 55.3 3.0 9.9e-15 54.0 2.1 1.8 1 0 0 1 1 1 1 G-patch domain R3H PF01424.17 KFM04858.1 - 6.9e-15 54.4 0.4 1.8e-14 53.1 0.3 1.8 1 0 0 1 1 1 1 R3H domain dsrm PF00035.20 KFM04858.1 - 1.3e-09 38.5 17.2 3.1e-05 24.4 0.1 4.6 5 0 0 5 5 5 3 Double-stranded RNA binding motif G-patch_2 PF12656.2 KFM04858.1 - 1.7e-05 24.5 0.8 5.7e-05 22.8 0.5 1.9 1 0 0 1 1 1 1 DExH-box splicing factor binding site DUF3469 PF11952.3 KFM04858.1 - 0.06 13.0 0.9 1.6 8.4 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3469) UQ_con PF00179.21 KFM04859.1 - 2.7e-40 137.0 0.3 4.4e-40 136.3 0.2 1.4 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFM04859.1 - 1.2e-06 28.3 0.0 1.5e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KFM04859.1 - 0.00053 19.8 0.1 0.00075 19.3 0.1 1.5 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 KFM04859.1 - 0.0076 15.9 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 UEV domain GFA PF04828.9 KFM04860.1 - 0.16 11.9 0.5 1.3 8.9 0.1 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF4410 PF14366.1 KFM04860.1 - 0.44 10.2 2.5 0.8 9.4 1.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4410) Mito_carr PF00153.22 KFM04861.1 - 2.7e-57 190.4 1.3 1e-22 79.6 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.22 KFM04862.1 - 1.1e-59 198.1 0.3 1.3e-26 92.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Med31 PF05669.7 KFM04863.1 - 0.034 13.8 0.0 0.087 12.5 0.0 1.6 1 0 0 1 1 1 0 SOH1 HCaRG PF07258.9 KFM04865.1 - 2.7e-34 118.2 0.0 3e-34 118.0 0.0 1.0 1 0 0 1 1 1 1 HCaRG protein FluMu_gp41 PF10109.4 KFM04865.1 - 0.11 12.4 0.1 0.41 10.5 0.0 1.9 2 0 0 2 2 2 0 Mu-like prophage FluMu protein gp41 PmbA_TldD PF01523.11 KFM04866.1 - 0.04 13.1 3.2 0.063 12.5 2.2 1.2 1 0 0 1 1 1 0 Putative modulator of DNA gyrase Hex_IIIa PF02455.11 KFM04866.1 - 0.15 10.7 8.2 0.22 10.1 5.7 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) SOBP PF15279.1 KFM04866.1 - 0.39 11.0 9.8 0.59 10.4 6.8 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein CAF-1_p150 PF11600.3 KFM04866.1 - 0.51 9.6 20.1 0.48 9.7 13.1 1.6 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DDHD PF02862.12 KFM04866.1 - 1.1 8.9 8.5 1.7 8.3 5.9 1.3 1 0 0 1 1 1 0 DDHD domain TIR PF01582.15 KFM04867.1 - 1.5e-29 102.2 0.1 4.2e-29 100.8 0.1 1.8 2 0 0 2 2 2 1 TIR domain I-set PF07679.11 KFM04867.1 - 5.1e-21 74.3 0.1 8.1e-06 25.6 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM04867.1 - 1.2e-17 63.7 0.0 5.7e-06 26.3 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 KFM04867.1 - 5.4e-14 52.4 0.0 6.4e-05 23.3 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.20 KFM04867.1 - 1.6e-12 47.3 0.1 0.00093 19.2 0.1 3.8 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 KFM04867.1 - 4.6e-12 45.8 0.0 0.0069 16.2 0.0 3.8 3 0 0 3 3 3 3 Immunoglobulin V-set domain TIR_2 PF13676.1 KFM04867.1 - 8.6e-05 22.6 0.0 0.00022 21.3 0.0 1.6 1 0 0 1 1 1 1 TIR domain V-set_CD47 PF08204.6 KFM04867.1 - 0.00028 20.6 2.4 0.068 12.9 0.0 3.5 4 0 0 4 4 4 1 CD47 immunoglobulin-like domain Herpes_gE PF02480.11 KFM04867.1 - 0.0016 16.7 0.0 1.4 7.1 0.0 2.8 2 1 1 3 3 3 2 Alphaherpesvirus glycoprotein E Pkinase PF00069.20 KFM04868.1 - 2.4e-57 194.0 0.0 5e-57 192.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain CNH PF00780.17 KFM04868.1 - 2.5e-53 181.2 0.0 4.8e-53 180.3 0.0 1.5 1 0 0 1 1 1 1 CNH domain Pkinase_Tyr PF07714.12 KFM04868.1 - 8.5e-41 139.7 0.0 1.4e-40 139.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM04868.1 - 6e-05 22.1 0.0 0.00012 21.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFM04868.1 - 0.23 11.1 0.1 0.23 11.1 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family tRNA_anti-codon PF01336.20 KFM04869.1 - 0.011 15.5 0.0 0.054 13.3 0.0 2.2 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain zf-RING_2 PF13639.1 KFM04870.1 - 1.9e-13 49.9 7.5 3.2e-13 49.2 5.2 1.4 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 KFM04870.1 - 5.3e-11 42.1 0.0 9.6e-11 41.2 0.0 1.4 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.2 KFM04870.1 - 2e-09 37.4 1.5 4.1e-09 36.4 1.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KFM04870.1 - 3.3e-07 29.8 7.6 5.7e-07 29.0 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM04870.1 - 4.5e-07 29.4 8.8 7.5e-07 28.7 6.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFM04870.1 - 8.2e-07 28.9 8.6 1.4e-06 28.1 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM04870.1 - 7.3e-06 25.5 6.8 1.2e-05 24.8 4.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF1251 PF06856.6 KFM04870.1 - 0.0022 17.4 0.1 0.007 15.8 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1251) Spc24 PF08286.6 KFM04870.1 - 0.0035 17.0 0.1 1.3 8.7 0.0 2.5 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 zf-Apc11 PF12861.2 KFM04870.1 - 0.0074 16.0 3.1 0.014 15.1 2.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2254 PF10011.4 KFM04870.1 - 0.023 13.1 0.0 0.037 12.4 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) SieB PF14163.1 KFM04870.1 - 0.024 14.2 0.1 0.039 13.5 0.1 1.3 1 0 0 1 1 1 0 Superinfection exclusion protein B Ndc1_Nup PF09531.5 KFM04870.1 - 0.12 10.7 0.1 0.18 10.2 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CcmD PF04995.9 KFM04870.1 - 0.15 11.7 1.6 0.21 11.3 0.7 1.6 1 1 0 1 1 1 0 Heme exporter protein D (CcmD) PHD PF00628.24 KFM04870.1 - 0.47 10.1 8.0 0.86 9.3 5.5 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.1 KFM04870.1 - 5.8 6.7 8.8 14 5.5 6.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger RabGAP-TBC PF00566.13 KFM04871.1 - 7.6e-46 156.2 2.7 1.4e-45 155.3 0.0 2.7 3 0 0 3 3 3 1 Rab-GTPase-TBC domain GRAM PF02893.15 KFM04871.1 - 8.9e-29 98.8 0.7 4.6e-15 54.8 0.1 2.7 2 0 0 2 2 2 2 GRAM domain PAS_11 PF14598.1 KFM04872.1 - 7e-26 90.3 1.9 1.1e-21 76.7 0.0 3.4 3 0 0 3 3 3 2 PAS domain PAS_3 PF08447.6 KFM04872.1 - 4.2e-18 65.2 0.1 5.8e-15 55.1 0.1 2.9 3 0 0 3 3 3 2 PAS fold PAS PF00989.19 KFM04872.1 - 2.5e-11 43.3 0.0 3.8e-08 33.0 0.0 3.1 3 0 0 3 3 3 2 PAS fold HLH PF00010.21 KFM04872.1 - 6.1e-08 32.2 0.6 1.3e-07 31.1 0.4 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.1 KFM04872.1 - 1e-05 25.8 0.0 0.00022 21.5 0.0 2.8 2 1 1 3 3 3 1 PAS domain PAS_4 PF08448.5 KFM04872.1 - 0.021 14.8 0.1 0.62 10.1 0.0 2.9 3 0 0 3 3 3 0 PAS fold Macoilin PF09726.4 KFM04872.1 - 5.6 5.1 8.0 13 3.9 5.5 1.5 1 1 0 1 1 1 0 Transmembrane protein VMA21 PF09446.5 KFM04873.1 - 3.2e-23 81.4 7.0 3.5e-23 81.2 4.9 1.0 1 0 0 1 1 1 1 VMA21-like domain PAP2_3 PF14378.1 KFM04873.1 - 0.018 14.5 0.2 0.026 14.0 0.2 1.2 1 0 0 1 1 1 0 PAP2 superfamily BCD PF15461.1 KFM04873.1 - 0.024 14.0 0.2 0.027 13.8 0.1 1.0 1 0 0 1 1 1 0 Beta-carotene 15,15'-dioxygenase TctB PF07331.6 KFM04873.1 - 0.049 13.2 5.4 0.06 12.9 3.7 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family 7tm_7 PF08395.7 KFM04873.1 - 0.19 10.6 1.9 0.2 10.6 1.3 1.0 1 0 0 1 1 1 0 7tm Chemosensory receptor 7tm_1 PF00001.16 KFM04874.1 - 1.9e-43 148.4 26.5 2.3e-43 148.1 18.3 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 KFM04874.1 - 3.2e-07 29.7 24.7 4.5e-07 29.2 17.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF3980 PF13140.1 KFM04874.1 - 1.3 9.3 15.0 3.6 7.9 3.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3980) Git3 PF11710.3 KFM04874.1 - 2.5 7.6 23.3 1.9 7.9 10.3 2.2 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 HMG_box_2 PF09011.5 KFM04875.1 - 1.7e-50 169.2 11.1 7e-30 103.2 5.5 2.4 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.14 KFM04875.1 - 2e-43 146.4 10.1 1.4e-27 95.6 0.1 2.5 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_5 PF14887.1 KFM04875.1 - 6.2e-05 22.7 11.0 0.018 14.8 1.9 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box 5 Nucleoplasmin PF03066.10 KFM04875.1 - 0.38 10.2 11.1 0.68 9.4 7.7 1.5 1 0 0 1 1 1 0 Nucleoplasmin YABBY PF04690.8 KFM04875.1 - 0.91 9.7 4.4 0.3 11.2 0.4 2.1 2 1 1 3 3 3 0 YABBY protein EBV-NA3 PF05009.7 KFM04875.1 - 7.2 5.7 6.6 12 5.1 4.5 1.4 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) CD99L2 PF12301.3 KFM04876.1 - 7.6e-46 155.8 2.5 8.8e-46 155.6 1.8 1.0 1 0 0 1 1 1 1 CD99 antigen like protein 2 ACT_7 PF13840.1 KFM04876.1 - 0.05 13.1 0.9 0.073 12.6 0.1 1.6 2 0 0 2 2 2 0 ACT domain DUF2953 PF11167.3 KFM04876.1 - 0.072 13.0 0.1 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) Bacteriocin_IIc PF10439.4 KFM04876.1 - 0.075 13.1 1.6 0.11 12.5 1.1 1.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Myotub-related PF06602.9 KFM04877.1 - 1.5e-146 487.7 0.0 1.9e-146 487.4 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.15 KFM04877.1 - 1.8e-08 33.7 0.0 3.7e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 GRAM domain Y_phosphatase PF00102.22 KFM04877.1 - 0.00017 20.9 0.0 0.00037 19.9 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KFM04877.1 - 0.00035 20.8 0.0 0.0007 19.8 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 KFM04877.1 - 0.00065 19.2 0.0 0.0016 18.0 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF4441 PF14536.1 KFM04877.1 - 0.081 12.9 0.9 0.19 11.6 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4441) Myotub-related PF06602.9 KFM04878.1 - 8.1e-147 488.6 0.1 1.1e-146 488.1 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.15 KFM04878.1 - 5.8e-13 48.1 0.0 1.4e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 GRAM domain Y_phosphatase PF00102.22 KFM04878.1 - 0.00026 20.4 0.0 0.00054 19.3 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFM04878.1 - 0.00046 19.7 0.0 0.00092 18.7 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFM04878.1 - 0.0034 17.6 0.0 0.0084 16.3 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family 3-PAP PF12578.3 KFM04878.1 - 0.021 14.6 0.7 0.055 13.3 0.2 1.8 1 1 0 1 1 1 0 Myotubularin-associated protein PGC7_Stella PF15549.1 KFM04879.1 - 0.39 10.6 19.2 0.028 14.4 7.5 3.2 2 1 0 2 2 2 0 PGC7/Stella/Dppa3 domain ASCH PF04266.9 KFM04880.1 - 0.017 15.4 0.0 0.019 15.3 0.0 1.2 1 0 0 1 1 1 0 ASCH domain Tmemb_185A PF10269.4 KFM04881.1 - 1.3e-69 234.4 27.2 1.3e-69 234.4 18.8 1.4 2 0 0 2 2 2 1 Transmembrane Fragile-X-F protein Sulfatase PF00884.18 KFM04882.1 - 1.2e-49 169.1 0.0 1.8e-49 168.6 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KFM04882.1 - 9.2e-09 35.0 0.0 0.00017 21.0 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KFM04882.1 - 0.0026 16.2 0.0 0.017 13.5 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF229) AF-4 PF05110.8 KFM04883.1 - 9.2e-214 712.7 75.9 1e-213 712.6 52.6 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein AF-4 PF05110.8 KFM04884.1 - 1e-94 318.5 22.9 1.3e-59 202.2 9.7 2.0 1 1 1 2 2 2 2 AF-4 proto-oncoprotein FXR1P_C PF12235.3 KFM04885.1 - 2.9e-56 189.9 25.0 2.9e-56 189.9 17.3 1.7 2 0 0 2 2 2 1 Fragile X-related 1 protein C terminal KH_1 PF00013.24 KFM04885.1 - 1.8e-19 69.1 0.7 2.2e-09 36.8 0.8 2.5 2 0 0 2 2 2 2 KH domain Agenet PF05641.7 KFM04885.1 - 5.3e-09 36.0 0.4 1.2e-08 34.9 0.3 1.7 1 0 0 1 1 1 1 Agenet domain KH_3 PF13014.1 KFM04885.1 - 4.9e-06 26.0 0.9 6.7e-05 22.4 0.4 2.7 2 0 0 2 2 2 1 KH domain KH_2 PF07650.12 KFM04885.1 - 0.00033 20.1 0.4 0.13 11.7 0.0 2.5 2 0 0 2 2 2 2 KH domain KH_4 PF13083.1 KFM04885.1 - 0.013 15.1 1.1 1.5 8.5 0.2 3.5 2 1 1 3 3 3 0 KH domain LRR_8 PF13855.1 KFM04887.1 - 1.3e-43 146.6 37.6 2.1e-16 59.4 1.0 6.6 3 2 4 7 7 7 5 Leucine rich repeat LRR_4 PF12799.2 KFM04887.1 - 2.6e-20 71.6 39.9 0.00027 20.4 0.5 7.2 5 1 4 9 9 9 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFM04887.1 - 3.1e-18 65.7 0.0 2.6e-08 33.6 0.0 2.3 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_1 PF00560.28 KFM04887.1 - 1.7e-15 54.6 35.9 0.14 12.2 0.3 12.4 12 0 0 12 12 12 6 Leucine Rich Repeat LRRNT PF01462.13 KFM04887.1 - 0.0086 15.5 2.1 0.0086 15.5 1.4 2.9 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain Sialidase PF02973.11 KFM04887.1 - 0.028 13.4 0.1 0.13 11.2 0.0 2.1 2 0 0 2 2 2 0 Sialidase, N-terminal domain IncA PF04156.9 KFM04887.1 - 0.092 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 IncA protein LRR_9 PF14580.1 KFM04887.1 - 0.62 9.6 10.1 8.5 5.9 0.5 3.6 2 2 1 3 3 3 0 Leucine-rich repeat LRR_7 PF13504.1 KFM04887.1 - 8.9 7.0 42.2 1.6 9.2 0.7 9.9 10 0 0 10 10 10 0 Leucine rich repeat LRR_8 PF13855.1 KFM04888.1 - 1.7e-72 239.0 84.0 3.1e-17 62.0 1.1 6.5 2 2 7 9 9 9 9 Leucine rich repeat LRR_4 PF12799.2 KFM04888.1 - 1.8e-30 104.0 34.3 4.2e-10 39.0 0.1 7.8 3 2 5 9 9 9 9 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFM04888.1 - 2.8e-16 59.3 0.4 7.6e-08 32.1 0.6 2.5 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_1 PF00560.28 KFM04888.1 - 6.6e-13 46.7 39.4 0.043 13.8 0.0 12.9 13 0 0 13 13 13 5 Leucine Rich Repeat LRRNT PF01462.13 KFM04888.1 - 0.00032 20.0 4.1 0.00032 20.0 2.8 2.2 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_7 PF13504.1 KFM04888.1 - 0.0034 17.3 40.3 1.1 9.7 0.2 10.6 11 0 0 11 11 11 3 Leucine rich repeat LRR_9 PF14580.1 KFM04888.1 - 0.016 14.7 10.9 1.6 8.2 0.3 3.8 2 2 2 4 4 4 0 Leucine-rich repeat SOXp PF12336.3 KFM04890.1 - 8.1e-33 112.8 2.4 8.1e-33 112.8 1.7 2.3 1 1 1 2 2 2 1 SOX transcription factor HMG_box PF00505.14 KFM04890.1 - 5.5e-27 93.8 4.5 5.9e-27 93.7 2.2 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFM04890.1 - 2.8e-11 43.6 1.9 4.3e-11 43.0 1.3 1.3 1 0 0 1 1 1 1 HMG-box domain Neur_chan_memb PF02932.11 KFM04891.1 - 2e-56 191.5 0.0 3.2e-56 190.8 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 KFM04891.1 - 5.1e-39 133.6 0.1 7e-39 133.2 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_LBD PF02931.18 KFM04892.1 - 9.1e-50 168.8 0.0 1.3e-49 168.2 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFM04892.1 - 2.9e-46 158.2 5.7 3.2e-38 131.9 2.3 2.1 1 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Med6 PF04934.9 KFM04892.1 - 0.092 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 MED6 mediator sub complex component Neur_chan_memb PF02932.11 KFM04893.1 - 2.1e-46 158.7 3.3 1.5e-40 139.6 0.5 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 KFM04893.1 - 5e-39 133.6 1.6 7.8e-39 133.0 1.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain cNMP_binding PF00027.24 KFM04894.1 - 5.5e-18 64.5 0.0 1e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.26 KFM04894.1 - 8.9e-18 64.2 3.0 1.3e-17 63.7 2.1 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.11 KFM04894.1 - 0.08 12.6 7.0 0.27 10.9 4.9 2.0 1 1 0 1 1 1 0 Ion channel Miff PF05644.6 KFM04895.1 - 2.1e-09 37.3 0.0 2.4e-09 37.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial and peroxisomal fission factor Mff Gla PF00594.15 KFM04896.1 - 4.1e-15 55.1 5.4 4.1e-15 55.1 3.7 1.7 2 0 0 2 2 2 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain Shisa PF13908.1 KFM04896.1 - 0.0078 16.4 1.1 0.051 13.7 0.8 2.0 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator T2SM PF04612.7 KFM04896.1 - 0.01 15.6 0.2 0.016 15.0 0.1 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Herpes_gE PF02480.11 KFM04896.1 - 0.016 13.4 0.0 0.02 13.1 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SKG6 PF08693.5 KFM04896.1 - 0.92 8.8 6.9 1.6 8.1 4.8 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain WWbp PF10349.4 KFM04896.1 - 4.3 8.2 7.2 9.5 7.1 5.0 1.7 1 1 0 1 1 1 0 WW-domain ligand protein Ripply PF14998.1 KFM04897.1 - 1.4e-24 86.0 0.0 1.6e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 Transcription Regulator PMP22_Claudin PF00822.15 KFM04898.1 - 2.4e-25 89.1 6.6 2.9e-25 88.8 4.6 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFM04898.1 - 7.3e-08 32.2 5.5 9.1e-08 31.9 3.5 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 KFM04898.1 - 0.073 12.6 6.7 0.1 12.2 4.2 1.7 1 1 1 2 2 2 0 Amastin surface glycoprotein DUF872 PF05915.7 KFM04898.1 - 0.88 9.4 3.6 0.28 11.0 0.1 2.0 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) ATP_synt_I PF03899.10 KFM04898.1 - 1.5 8.9 5.8 0.22 11.6 0.8 1.9 2 0 0 2 2 2 0 ATP synthase I chain RRM_6 PF14259.1 KFM04899.1 - 1.4e-06 28.1 0.0 3.3e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFM04899.1 - 5.4e-06 25.9 0.0 1.3e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM04899.1 - 0.0017 18.1 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nsp1_C PF05064.8 KFM04900.1 - 1.5e-40 137.4 7.8 3.5e-40 136.2 5.4 1.6 1 0 0 1 1 1 1 Nsp1-like C-terminal region Prp18 PF02840.10 KFM04900.1 - 0.59 9.9 7.7 5.2 6.8 1.9 2.2 1 1 1 2 2 2 0 Prp18 domain DUF4164 PF13747.1 KFM04900.1 - 1.1 9.4 9.9 0.078 13.1 1.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Laminin_II PF06009.7 KFM04900.1 - 3.4 7.4 9.2 3.4 7.4 0.7 2.3 1 1 0 2 2 2 0 Laminin Domain II DUF1664 PF07889.7 KFM04900.1 - 9.8 6.0 11.7 2.1 8.1 2.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) PIH1 PF08190.7 KFM04901.1 - 4.4e-10 39.5 0.0 4.7e-10 39.4 0.0 1.0 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 FERM_N PF09379.5 KFM04902.1 - 3.7e-07 30.0 0.1 4.7e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 FERM N-terminal domain DUF2042 PF09743.4 KFM04903.1 - 4.6e-24 85.1 0.8 7.7e-23 81.1 0.0 2.7 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2042) FRG2 PF15315.1 KFM04903.1 - 0.5 10.3 6.0 1 9.2 4.2 1.5 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 LIM PF00412.17 KFM04904.1 - 7.7e-47 157.1 69.1 9.8e-13 47.9 4.5 5.1 5 0 0 5 5 5 5 LIM domain 7tm_1 PF00001.16 KFM04905.1 - 1.8e-49 168.2 24.5 2.4e-49 167.7 17.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM04905.1 - 4.4e-07 29.3 25.2 7.6e-07 28.5 17.5 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF756 PF05506.7 KFM04905.1 - 0.034 14.6 0.0 0.064 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF756) zf-LITAF-like PF10601.4 KFM04905.1 - 9.7 6.1 9.3 21 5.0 0.6 3.5 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain UPF0240 PF06784.6 KFM04907.1 - 1.9e-36 125.3 0.1 2.1e-36 125.2 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0240) NAP PF00956.13 KFM04907.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) Kelch_1 PF01344.20 KFM04908.1 - 2.3e-39 132.6 9.4 8.2e-09 34.8 0.0 6.6 6 1 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 KFM04908.1 - 1.7e-35 119.7 4.5 5.1e-08 32.7 0.0 7.0 2 1 4 6 6 6 5 Kelch motif BTB PF00651.26 KFM04908.1 - 2.2e-27 95.2 1.4 1.5e-26 92.5 0.2 2.4 1 1 1 2 2 2 1 BTB/POZ domain Kelch_4 PF13418.1 KFM04908.1 - 7.1e-19 67.3 7.1 0.0039 16.9 0.0 6.7 7 0 0 7 7 7 5 Galactose oxidase, central domain BACK PF07707.10 KFM04908.1 - 4.2e-17 61.8 1.6 1e-16 60.6 1.1 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_2 PF07646.10 KFM04908.1 - 2.1e-16 58.9 2.3 0.028 14.2 0.0 5.7 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.1 KFM04908.1 - 4.5e-16 58.4 3.4 0.034 14.1 0.1 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 KFM04908.1 - 7.7e-16 57.7 6.1 0.001 19.2 0.0 7.0 6 1 0 6 6 6 4 Galactose oxidase, central domain MMS22L_N PF14910.1 KFM04909.1 - 0 1207.8 19.9 0 1207.5 13.8 1.1 1 0 0 1 1 1 1 S-phase genomic integrity recombination mediator, N-terminal MMS22L_C PF14911.1 KFM04909.1 - 2.1e-121 405.5 2.0 5.5e-121 404.1 1.4 1.8 1 0 0 1 1 1 1 S-phase genomic integrity recombination mediator, C-terminal Pou PF00157.12 KFM04910.1 - 2.3e-25 88.0 0.0 4.5e-25 87.1 0.0 1.5 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.24 KFM04910.1 - 1.7e-19 69.1 0.3 3.1e-19 68.3 0.2 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFM04910.1 - 0.011 15.4 0.0 0.025 14.2 0.0 1.6 1 0 0 1 1 1 0 Homeobox KN domain LRR_4 PF12799.2 KFM04911.1 - 1.1e-08 34.5 10.7 0.038 13.6 0.0 6.0 2 1 4 7 7 7 5 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KFM04911.1 - 2.8e-08 33.3 2.8 1.4e-07 31.1 1.9 2.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFM04911.1 - 4.4e-08 32.5 0.4 4.4e-08 32.5 0.3 2.8 3 0 0 3 3 3 1 F-box domain LRR_8 PF13855.1 KFM04911.1 - 2e-07 30.6 15.8 0.0056 16.4 0.7 5.6 2 1 5 7 7 7 6 Leucine rich repeat LRR_6 PF13516.1 KFM04911.1 - 4.1e-06 26.3 18.8 0.25 11.5 0.0 8.0 9 0 0 9 9 9 2 Leucine Rich repeat LRR_1 PF00560.28 KFM04911.1 - 7.3e-06 25.3 10.7 6.3 7.2 0.1 8.0 6 2 0 6 6 6 2 Leucine Rich Repeat LRR_7 PF13504.1 KFM04911.1 - 0.00044 19.9 13.3 8.3 7.1 0.0 8.1 6 2 1 7 7 7 2 Leucine rich repeat PRANC PF09372.5 KFM04911.1 - 0.043 13.7 0.3 0.17 11.8 0.0 2.2 2 0 0 2 2 2 0 PRANC domain Adeno_E3_CR2 PF02439.10 KFM04911.1 - 0.22 11.1 0.9 0.41 10.2 0.6 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 GST_C_3 PF14497.1 KFM04912.1 - 3.9e-19 68.9 0.0 8.6e-19 67.8 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFM04912.1 - 1.2e-05 25.0 0.0 2.3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.4 KFM04912.1 - 0.00058 20.0 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_3 PF13417.1 KFM04912.1 - 0.0019 18.4 0.0 0.043 14.0 0.0 2.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Methyltransf_23 PF13489.1 KFM04913.1 - 1.1e-22 80.5 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFM04913.1 - 2.5e-18 66.3 0.0 4.3e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFM04913.1 - 4.7e-16 58.7 0.0 6e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFM04913.1 - 5e-15 55.7 0.0 8.3e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFM04913.1 - 3e-12 47.1 0.0 4.3e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KFM04913.1 - 3.8e-08 32.7 0.0 5.4e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 KFM04913.1 - 4e-07 30.3 0.0 6.7e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KFM04913.1 - 8.1e-07 28.4 0.0 1.1e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.6 KFM04913.1 - 7.1e-06 25.5 0.0 1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.9 KFM04913.1 - 1.1e-05 24.8 0.0 2.1e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 KFM04913.1 - 2.6e-05 23.4 0.0 4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KFM04913.1 - 9.4e-05 22.4 0.0 0.00017 21.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KFM04913.1 - 0.00071 18.3 0.0 0.0012 17.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_16 PF10294.4 KFM04913.1 - 0.0013 18.1 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_PK PF05891.7 KFM04913.1 - 0.0052 16.1 0.0 0.0069 15.7 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase TehB PF03848.9 KFM04913.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 KFM04913.1 - 0.12 12.0 0.2 0.42 10.3 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain UCH PF00443.24 KFM04916.1 - 2.2e-49 168.0 3.1 3.7e-49 167.2 2.2 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KFM04916.1 - 1.5e-17 63.4 8.8 1.5e-17 63.4 6.1 2.8 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 KFM04916.1 - 9.9e-14 51.4 12.2 5.4e-11 42.4 8.5 2.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF1086 PF06461.6 KFM04916.1 - 0.29 10.9 2.2 11 5.8 0.0 3.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1086) Rhodanese PF00581.15 KFM04917.1 - 1.6e-08 34.8 0.0 1.8e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Cyclin_N PF00134.18 KFM04918.1 - 9.6e-15 54.2 2.9 1e-12 47.7 0.5 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFM04918.1 - 0.00093 19.1 1.0 0.028 14.3 0.0 2.8 1 1 1 3 3 3 1 Cyclin, C-terminal domain TFIIB PF00382.14 KFM04918.1 - 0.01 15.6 0.2 0.14 12.0 0.0 2.2 2 0 0 2 2 2 0 Transcription factor TFIIB repeat SET PF00856.23 KFM04919.1 - 0.00031 21.0 0.0 0.00039 20.7 0.0 1.3 1 0 0 1 1 1 1 SET domain Ribosomal_S24e PF01282.14 KFM04920.1 - 5.3e-38 128.6 0.3 8.1e-38 128.1 0.1 1.3 1 1 0 1 1 1 1 Ribosomal protein S24e DUF4519 PF15012.1 KFM04920.1 - 0.3 11.0 6.9 0.76 9.7 4.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) zf-MIZ PF02891.15 KFM04921.1 - 9.9e-23 79.4 4.8 9.9e-23 79.4 3.3 2.2 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 KFM04921.1 - 4.1e-05 23.0 1.3 4.1e-05 23.0 0.9 2.1 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Pro_isomerase PF00160.16 KFM04922.1 - 6.5e-45 153.1 0.4 7.2e-45 152.9 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-CCHC_2 PF13696.1 KFM04923.1 - 2.9e-20 71.4 7.7 2.9e-20 71.4 5.3 2.8 4 0 0 4 4 4 1 Zinc knuckle zf-3CxxC PF13695.1 KFM04923.1 - 5.1e-13 49.0 11.6 5.1e-12 45.8 7.8 2.5 2 1 0 2 2 2 1 Zinc-binding domain UPF0515 PF15135.1 KFM04923.1 - 6.4e-05 22.1 8.6 8.2e-05 21.8 5.9 1.2 1 0 0 1 1 1 1 Uncharacterised protein UPF0515 Cytochrom_c3_2 PF14537.1 KFM04923.1 - 5.6 7.3 10.8 1.1 9.6 4.6 1.8 1 1 0 1 1 1 0 Cytochrome c3 Tachystatin_B PF11478.3 KFM04923.1 - 7.7 6.3 8.3 18 5.1 1.6 2.5 2 0 0 2 2 2 0 Antimicrobial chitin binding protein tachystatin B Annexin PF00191.15 KFM04924.1 - 2.4e-101 331.6 11.7 6e-26 90.1 0.2 4.1 4 0 0 4 4 4 4 Annexin PLAC9 PF15205.1 KFM04925.1 - 1.6e-14 53.9 0.1 1.6e-14 53.8 0.1 1.0 1 0 0 1 1 1 1 Placenta-specific protein 9 TRL PF13146.1 KFM04925.1 - 0.085 12.8 0.2 0.1 12.5 0.1 1.1 1 0 0 1 1 1 0 TRL-like protein family Rabaptin PF03528.10 KFM04925.1 - 0.097 12.5 0.2 0.11 12.4 0.1 1.0 1 0 0 1 1 1 0 Rabaptin PALP PF00291.20 KFM04926.1 - 7.6e-56 189.5 0.2 9e-56 189.3 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACT_6 PF13740.1 KFM04926.1 - 0.0036 16.9 0.0 0.011 15.4 0.0 1.8 1 0 0 1 1 1 1 ACT domain APC_crr PF05923.7 KFM04926.1 - 1.6 8.4 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 APC cysteine-rich region DUF4499 PF14934.1 KFM04927.1 - 9.1e-33 112.0 5.2 1e-32 111.9 3.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) GBP PF02263.14 KFM04928.1 - 3.7e-106 353.9 0.0 6.8e-106 353.0 0.0 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.9 KFM04928.1 - 1.9e-80 270.2 11.9 2.8e-80 269.6 8.2 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain AAA_14 PF13173.1 KFM04928.1 - 0.0011 18.8 0.1 0.021 14.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_35 PF14516.1 KFM04928.1 - 0.0035 16.0 0.2 0.014 14.0 0.0 1.9 2 0 0 2 2 2 1 AAA-like domain MMR_HSR1 PF01926.18 KFM04928.1 - 0.013 15.4 0.0 0.062 13.2 0.0 2.2 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_17 PF13207.1 KFM04928.1 - 0.014 16.2 1.4 0.14 12.9 0.0 2.8 3 1 0 3 3 3 0 AAA domain AAA_28 PF13521.1 KFM04928.1 - 0.035 14.0 0.0 0.035 14.0 0.0 3.3 4 0 0 4 4 4 0 AAA domain zf-RING_UBOX PF13445.1 KFM04928.1 - 0.037 13.7 0.7 0.13 12.0 0.0 2.4 2 0 0 2 2 2 0 RING-type zinc-finger AAA_22 PF13401.1 KFM04928.1 - 0.055 13.6 0.3 0.3 11.2 0.0 2.3 3 0 0 3 3 3 0 AAA domain RHD3 PF05879.7 KFM04928.1 - 0.13 10.1 0.0 0.13 10.1 0.0 3.0 3 0 0 3 3 3 0 Root hair defective 3 GTP-binding protein (RHD3) Pkinase_Tyr PF07714.12 KFM04929.1 - 8e-37 126.7 0.0 1.1e-36 126.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM04929.1 - 1.8e-35 122.3 0.0 2.9e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain CARD PF00619.16 KFM04929.1 - 4.5e-18 64.8 0.4 8.6e-18 63.9 0.3 1.5 1 0 0 1 1 1 1 Caspase recruitment domain EB1_binding PF05937.6 KFM04929.1 - 0.093 13.1 1.0 4 7.7 0.4 2.2 2 0 0 2 2 2 0 EB-1 Binding Domain APH PF01636.18 KFM04929.1 - 0.17 11.5 0.1 0.32 10.6 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family AA_permease_2 PF13520.1 KFM04930.1 - 4.7e-64 216.4 36.5 5.7e-64 216.2 25.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFM04930.1 - 1.7e-27 95.9 32.4 2.3e-27 95.5 22.4 1.2 1 0 0 1 1 1 1 Amino acid permease Pyr_redox_3 PF13738.1 KFM04931.1 - 4.1e-07 30.2 0.0 2.3e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFM04931.1 - 0.00078 19.3 0.0 0.1 12.4 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Nbs1_C PF08599.5 KFM04932.1 - 1e-36 124.6 2.0 1.3e-36 124.3 0.1 2.3 2 0 0 2 2 2 1 DNA damage repair protein Nbs1 FHA PF00498.21 KFM04932.1 - 3e-15 56.0 0.2 6.9e-15 54.9 0.1 1.7 1 0 0 1 1 1 1 FHA domain BRCT PF00533.21 KFM04932.1 - 2.2e-09 37.3 0.1 2.6e-07 30.6 0.0 2.7 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KFM04932.1 - 0.00031 20.5 0.1 0.0006 19.6 0.1 1.5 1 0 0 1 1 1 1 twin BRCT domain adh_short_C2 PF13561.1 KFM04933.1 - 1.5e-25 90.3 0.2 2e-25 89.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFM04933.1 - 3.2e-20 72.6 1.2 4.3e-20 72.2 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFM04933.1 - 4.7e-07 29.6 0.3 7.8e-07 28.9 0.2 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KFM04933.1 - 0.0003 20.2 0.1 0.00048 19.6 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFM04933.1 - 0.0039 15.9 0.1 0.0057 15.3 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 KFM04933.1 - 0.071 12.0 0.1 0.099 11.6 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase EF-hand_1 PF00036.27 KFM04934.1 - 1.8e-23 79.9 10.7 1.3e-07 30.4 0.7 5.4 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 KFM04934.1 - 9.1e-23 78.0 9.8 2e-07 30.3 0.4 5.4 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.1 KFM04934.1 - 1.8e-22 79.2 7.3 1.6e-10 40.9 1.1 3.3 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 KFM04934.1 - 2.1e-14 52.1 7.9 0.00019 20.6 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 KFM04934.1 - 2.3e-08 33.4 9.9 2.9e-06 26.8 0.5 3.2 4 1 0 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFM04934.1 - 0.0016 18.4 2.9 1.1 9.3 0.0 3.3 2 1 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region DUF4299 PF14132.1 KFM04934.1 - 0.0028 16.8 1.0 0.0069 15.5 0.1 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4299) EF-hand_like PF09279.6 KFM04934.1 - 0.0035 17.3 7.1 0.83 9.7 0.1 3.5 3 1 0 3 3 3 2 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_3 PF09069.6 KFM04934.1 - 0.0094 16.0 0.2 1 9.4 0.0 2.9 3 0 0 3 3 3 1 EF-hand EF-hand_10 PF14788.1 KFM04934.1 - 0.028 14.0 9.4 2.1 8.0 0.3 4.3 3 1 1 4 4 4 0 EF hand LXG PF04740.7 KFM04934.1 - 0.032 14.0 5.7 0.58 9.9 0.5 2.8 2 1 1 3 3 3 0 LXG domain of WXG superfamily EF-hand_9 PF14658.1 KFM04934.1 - 0.12 12.3 0.1 31 4.5 0.0 3.2 2 1 1 3 3 3 0 EF-hand domain RE_Eco47II PF09553.5 KFM04934.1 - 0.2 10.7 2.7 5.6 6.0 0.2 2.4 2 0 0 2 2 2 0 Eco47II restriction endonuclease UPF0158 PF03682.8 KFM04934.1 - 0.22 11.1 0.1 0.22 11.1 0.1 2.7 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0158) SNARE_assoc PF09335.6 KFM04936.1 - 3.9e-17 62.6 6.5 3.9e-17 62.6 4.5 2.0 2 1 0 2 2 2 1 SNARE associated Golgi protein ABM PF03992.11 KFM04937.1 - 8.6e-10 38.5 0.0 1.6e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase EF-hand_1 PF00036.27 KFM04937.1 - 2.5e-05 23.2 0.9 0.31 10.4 0.0 3.5 2 1 0 3 3 3 2 EF hand DUF904 PF06005.7 KFM04937.1 - 2.7e-05 24.3 3.0 0.0016 18.7 0.0 3.2 2 2 0 2 2 1 1 Protein of unknown function (DUF904) EF-hand_8 PF13833.1 KFM04937.1 - 2.8e-05 23.6 1.0 0.0029 17.1 0.7 2.8 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KFM04937.1 - 0.00012 21.6 0.4 0.13 12.2 0.0 3.5 2 1 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.1 KFM04937.1 - 0.00039 20.4 4.4 0.032 14.3 0.9 3.1 2 1 0 2 2 2 1 EF-hand domain pair RraB PF06877.6 KFM04937.1 - 0.0023 18.5 1.1 0.0023 18.5 0.8 1.9 2 0 0 2 2 2 1 Regulator of ribonuclease activity B EF-hand_5 PF13202.1 KFM04937.1 - 0.011 15.0 1.6 0.28 10.5 0.0 3.1 2 1 1 3 3 3 0 EF hand MRP-L28 PF09812.4 KFM04937.1 - 0.015 15.0 0.7 0.015 15.0 0.5 2.2 2 1 0 2 2 2 0 Mitochondrial ribosomal protein L28 Rep_N PF08724.5 KFM04937.1 - 0.035 13.6 0.0 0.075 12.5 0.0 1.6 1 0 0 1 1 1 0 Rep protein catalytic domain like EF-hand_10 PF14788.1 KFM04937.1 - 0.06 13.0 1.1 2.5 7.8 0.3 3.4 3 1 0 3 3 3 0 EF hand DUF3829 PF12889.2 KFM04937.1 - 0.063 12.4 2.5 0.4 9.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) TerB PF05099.8 KFM04937.1 - 0.079 12.6 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Tellurite resistance protein TerB Exonuc_VII_S PF02609.11 KFM04937.1 - 0.47 10.2 9.1 0.68 9.7 0.3 3.5 2 1 1 3 3 3 0 Exonuclease VII small subunit YojJ PF10372.4 KFM04937.1 - 0.84 9.5 5.9 18 5.3 0.3 3.6 2 2 1 3 3 3 0 Bacterial membrane-spanning protein N-terminus AAA_23 PF13476.1 KFM04937.1 - 8.5 6.6 14.5 96 3.2 10.0 2.1 1 1 0 1 1 1 0 AAA domain eIF_4EBP PF05456.6 KFM04938.1 - 0.018 14.6 0.1 0.018 14.6 0.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Tmemb_55A PF09788.4 KFM04939.1 - 2.2e-105 351.4 18.1 2.4e-105 351.3 12.5 1.0 1 0 0 1 1 1 1 Transmembrane protein 55A PhnA_Zn_Ribbon PF08274.7 KFM04939.1 - 0.0023 17.6 1.2 7.3 6.4 0.3 3.7 3 1 0 3 3 3 1 PhnA Zinc-Ribbon zf-CHY PF05495.7 KFM04939.1 - 0.18 11.9 0.1 0.18 11.9 0.1 2.9 2 1 0 2 2 2 0 CHY zinc finger zf-BED PF02892.10 KFM04939.1 - 0.29 10.9 13.4 0.54 10.0 0.0 4.0 3 1 2 5 5 5 0 BED zinc finger IBR PF01485.16 KFM04939.1 - 0.32 10.9 20.4 1.3 8.9 0.2 3.8 2 1 2 4 4 4 0 IBR domain Zn-ribbon_8 PF09723.5 KFM04939.1 - 0.33 10.9 0.2 0.33 10.9 0.2 3.0 2 1 1 3 3 3 0 Zinc ribbon domain zinc_ribbon_5 PF13719.1 KFM04939.1 - 0.36 10.4 0.0 0.36 10.4 0.0 4.8 5 1 1 6 6 6 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KFM04939.1 - 0.36 10.5 0.0 0.36 10.5 0.0 4.8 5 1 1 6 6 6 0 zinc-ribbon domain zf-RING_3 PF14369.1 KFM04939.1 - 1.8 8.6 0.0 1.8 8.6 0.0 3.7 4 0 0 4 4 4 0 zinc-finger OTU PF02338.14 KFM04940.1 - 2e-12 47.7 0.1 2e-12 47.7 0.0 2.3 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 KFM04940.1 - 7.4e-06 25.4 2.0 0.041 13.2 0.0 2.8 1 1 1 3 3 3 2 Peptidase C65 Otubain DUF4090 PF13319.1 KFM04940.1 - 0.037 13.9 0.2 2.8 7.9 0.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4090) IFP_35_N PF07334.8 KFM04940.1 - 0.18 11.7 7.7 0.13 12.2 4.2 1.7 1 1 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus NHR2 PF08788.6 KFM04941.1 - 7.5e-38 127.8 9.3 2.3e-37 126.2 6.5 1.9 1 0 0 1 1 1 1 NHR2 domain like TAFH PF07531.9 KFM04941.1 - 5.9e-35 118.7 0.9 1.1e-34 117.8 0.6 1.5 1 0 0 1 1 1 1 NHR1 homology to TAF zf-MYND PF01753.13 KFM04941.1 - 8.4e-08 31.9 18.4 8.4e-08 31.9 12.7 2.0 2 0 0 2 2 2 1 MYND finger DUF3731 PF12531.3 KFM04941.1 - 0.18 11.2 5.3 0.04 13.4 1.1 1.7 2 0 0 2 2 2 0 DNA-K related protein vATP-synt_E PF01991.13 KFM04941.1 - 0.6 9.3 12.3 0.98 8.6 8.6 1.3 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit ATP-synt_B PF00430.13 KFM04941.1 - 8.4 6.2 13.0 17 5.1 9.0 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) TRIQK PF15168.1 KFM04942.1 - 5e-28 96.8 0.6 5.5e-28 96.7 0.4 1.0 1 0 0 1 1 1 1 Triple QxxK/R motif-containing protein family CoxIIa PF08113.6 KFM04942.1 - 0.081 12.6 1.6 0.11 12.2 1.1 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IIa family FAM92 PF06730.6 KFM04943.1 - 1.3e-109 364.7 10.5 1.6e-109 364.3 7.3 1.0 1 0 0 1 1 1 1 FAM92 protein BAR PF03114.13 KFM04943.1 - 0.00014 21.4 5.9 0.00024 20.6 4.0 1.4 1 1 0 1 1 1 1 BAR domain Vps5 PF09325.5 KFM04943.1 - 0.0022 17.3 6.7 0.098 11.8 4.7 2.8 1 1 0 1 1 1 1 Vps5 C terminal like P4Ha_N PF08336.6 KFM04943.1 - 0.0033 17.2 1.1 0.0033 17.2 0.8 2.0 1 1 1 2 2 2 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region HTH_42 PF06224.7 KFM04943.1 - 0.039 13.3 0.3 0.058 12.7 0.2 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain HAUS-augmin3 PF14932.1 KFM04943.1 - 0.19 10.8 8.5 0.036 13.2 3.0 1.8 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 3 YgaB PF14182.1 KFM04943.1 - 3.4 7.9 6.9 14 6.0 2.4 3.0 3 0 0 3 3 3 0 YgaB-like protein RRM_6 PF14259.1 KFM04944.1 - 3.7e-39 132.5 0.3 9.7e-12 44.7 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFM04944.1 - 1.1e-23 82.5 0.2 4.5e-06 26.2 0.2 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM04944.1 - 4.2e-08 32.9 0.0 0.1 12.4 0.0 4.2 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Meckelin PF09773.4 KFM04945.1 - 0 1012.8 12.9 0 1012.4 8.9 1.1 1 0 0 1 1 1 1 Meckelin (Transmembrane protein 67) Phage_tail_X PF05489.7 KFM04945.1 - 0.12 11.8 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 Phage Tail Protein X PP2C PF00481.16 KFM04946.1 - 1.2e-35 123.1 0.0 1.1e-34 119.9 0.0 2.1 1 1 1 2 2 2 1 Protein phosphatase 2C Rod_C PF10493.4 KFM04946.1 - 0.013 13.8 0.0 0.018 13.3 0.0 1.1 1 0 0 1 1 1 0 Rough deal protein C-terminal region Ras PF00071.17 KFM04947.1 - 3.6e-31 107.7 0.1 8.8e-31 106.4 0.0 1.7 2 0 0 2 2 2 1 Ras family Miro PF08477.8 KFM04947.1 - 8.4e-20 71.4 0.0 1.9e-19 70.2 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein FeoB_N PF02421.13 KFM04947.1 - 3.5e-05 23.1 0.1 0.00019 20.7 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.18 KFM04947.1 - 0.0016 18.3 0.0 0.0034 17.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KFM04947.1 - 0.029 14.3 0.2 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 KFM04947.1 - 0.04 14.2 0.0 0.076 13.3 0.0 1.8 1 1 0 1 1 1 0 ABC transporter Dynamin_N PF00350.18 KFM04947.1 - 0.048 13.4 0.3 0.048 13.4 0.2 2.1 3 0 0 3 3 3 0 Dynamin family AAA_22 PF13401.1 KFM04947.1 - 0.11 12.6 0.1 31 4.7 0.0 3.0 2 1 1 3 3 3 0 AAA domain Myb_DNA-bind_5 PF13873.1 KFM04948.1 - 4.1e-20 71.4 0.1 4.1e-20 71.4 0.0 2.9 3 1 0 3 3 3 1 Myb/SANT-like DNA-binding domain DUF1041 PF06292.12 KFM04948.1 - 0.0013 18.9 0.9 0.044 13.9 0.1 2.7 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1041) Myb_DNA-bind_4 PF13837.1 KFM04948.1 - 0.006 16.6 0.2 0.013 15.6 0.1 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain zf-TRAF PF02176.13 KFM04949.1 - 1.2e-08 35.2 3.6 1.2e-08 35.2 2.5 3.0 3 1 1 4 4 3 1 TRAF-type zinc finger zf-C3HC4 PF00097.20 KFM04949.1 - 1e-07 31.5 7.5 1e-07 31.5 5.2 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM04949.1 - 3e-07 30.1 8.2 3e-07 30.1 5.7 2.3 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 KFM04949.1 - 9.8e-07 28.5 6.1 9.8e-07 28.5 4.3 2.3 3 0 0 3 3 1 1 zinc finger of C3HC4-type, RING Sina PF03145.11 KFM04949.1 - 5.4e-06 26.2 7.1 0.0047 16.6 0.7 2.4 1 1 1 2 2 2 2 Seven in absentia protein family zf-C3HC4_2 PF13923.1 KFM04949.1 - 1.6e-05 24.8 7.6 1.6e-05 24.8 5.3 2.5 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM04949.1 - 3.3e-05 23.4 3.5 3.3e-05 23.4 2.4 2.7 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KFM04949.1 - 0.00013 21.6 1.8 0.00046 19.9 1.2 1.9 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 KFM04949.1 - 0.0012 18.5 4.9 0.0033 17.1 3.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 KFM04949.1 - 0.0013 18.3 5.6 0.0013 18.3 3.9 2.2 2 1 0 2 2 1 1 zinc-RING finger domain Fzo_mitofusin PF04799.8 KFM04949.1 - 0.095 12.0 4.1 0.17 11.2 2.8 1.4 1 0 0 1 1 1 0 fzo-like conserved region DUF3552 PF12072.3 KFM04949.1 - 0.11 11.7 11.3 0.15 11.2 7.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DBD_Tnp_Mut PF03108.10 KFM04949.1 - 0.11 12.0 1.4 0.34 10.5 0.0 2.3 2 0 0 2 2 2 0 MuDR family transposase Seryl_tRNA_N PF02403.17 KFM04949.1 - 0.39 10.7 10.8 3.9 7.5 6.3 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.7 KFM04949.1 - 0.72 9.6 4.5 1.2 8.8 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF904 PF06005.7 KFM04949.1 - 1.2 9.5 11.3 0.42 10.9 5.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Defensin_4 PF07936.7 KFM04949.1 - 1.5 8.5 5.9 6.3 6.5 0.5 2.6 2 0 0 2 2 2 0 Potassium-channel blocking toxin DM PF00751.13 KFM04949.1 - 3.4 7.2 13.4 0.34 10.4 0.4 3.2 2 1 1 3 3 2 0 DM DNA binding domain zf-rbx1 PF12678.2 KFM04949.1 - 3.6 7.7 22.6 0.069 13.2 6.1 3.9 2 2 0 2 2 2 0 RING-H2 zinc finger OmpH PF03938.9 KFM04949.1 - 3.9 7.3 7.7 6 6.7 5.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RRM_6 PF14259.1 KFM04951.1 - 2.2e-48 162.1 0.0 9.9e-16 57.4 0.0 3.7 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFM04951.1 - 3.3e-16 58.6 0.0 0.00036 20.0 0.0 3.7 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM04951.1 - 3.2e-06 26.8 0.2 0.27 11.1 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4283 PF14111.1 KFM04951.1 - 0.0013 17.8 0.1 0.047 12.7 0.0 3.4 4 1 1 5 5 5 1 Domain of unknown function (DUF4283) RNase_T PF00929.19 KFM04951.1 - 0.0062 16.8 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 Exonuclease Dpy19 PF10034.4 KFM04952.1 - 3e-207 689.7 29.0 3.5e-207 689.5 20.1 1.0 1 0 0 1 1 1 1 Q-cell neuroblast polarisation Cadherin PF00028.12 KFM04953.1 - 1.7e-206 669.2 19.0 6.9e-20 71.1 0.1 15.4 15 0 0 15 15 15 15 Cadherin domain Cadherin_C PF01049.12 KFM04953.1 - 4.7e-38 130.5 0.2 1.5e-37 128.8 0.1 1.9 1 0 0 1 1 1 1 Cadherin cytoplasmic region Laminin_G_2 PF02210.19 KFM04953.1 - 2.8e-37 127.6 3.1 3.9e-22 78.6 0.1 2.9 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.18 KFM04953.1 - 1.5e-26 92.9 0.1 1.7e-12 47.4 0.0 2.7 2 0 0 2 2 2 2 Laminin G domain Cadherin_pro PF08758.6 KFM04953.1 - 4.7e-12 45.5 0.0 4.2e-05 23.2 0.0 8.0 9 0 0 9 9 9 1 Cadherin prodomain like EGF PF00008.22 KFM04953.1 - 5e-11 42.3 47.9 4.5e-06 26.5 4.7 4.9 4 0 0 4 4 4 4 EGF-like domain Cadherin_2 PF08266.7 KFM04953.1 - 3.4e-07 29.7 0.0 0.61 9.7 0.0 6.6 7 0 0 7 7 7 2 Cadherin-like Y_Y_Y PF07495.8 KFM04953.1 - 4.8e-06 26.2 3.1 0.8 9.5 0.1 4.8 4 0 0 4 4 4 2 Y_Y_Y domain EGF_2 PF07974.8 KFM04953.1 - 0.00036 20.6 9.4 0.00036 20.6 6.5 4.3 4 0 0 4 4 4 3 EGF-like domain Big_3_4 PF13754.1 KFM04953.1 - 0.19 12.0 0.0 0.19 12.0 0.0 8.1 11 0 0 11 11 11 0 Bacterial Ig-like domain (group 3) TPR_2 PF07719.12 KFM04954.1 - 0.00033 20.3 4.0 0.25 11.3 0.2 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFM04954.1 - 0.0012 18.4 0.7 0.19 11.5 0.2 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFM04954.1 - 0.017 14.8 0.4 2.7 8.0 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFM04954.1 - 0.11 12.1 7.5 2.7 7.7 0.5 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Cyclin_N PF00134.18 KFM04955.1 - 8.2e-40 135.2 1.7 1.7e-39 134.2 1.2 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFM04955.1 - 1.4e-11 44.3 0.1 3.4e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain DOR PF14839.1 KFM04956.1 - 7.2e-79 264.5 0.5 8.3e-79 264.3 0.3 1.0 1 0 0 1 1 1 1 DOR family Thioredoxin_7 PF13899.1 KFM04956.1 - 0.058 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like SQS_PSY PF00494.14 KFM04957.1 - 3.8e-49 167.3 0.2 4.4e-49 167.1 0.1 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase FYVE PF01363.16 KFM04958.1 - 7.8e-20 70.5 7.6 1.9e-19 69.2 5.3 1.7 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 KFM04958.1 - 4.6e-12 46.0 0.1 9.6e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 PH domain FYVE_2 PF02318.11 KFM04958.1 - 0.00061 19.6 5.1 0.0011 18.8 3.5 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger zf-DHHC PF01529.15 KFM04958.1 - 0.041 13.2 2.2 0.069 12.5 1.5 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase PH_11 PF15413.1 KFM04958.1 - 0.11 12.7 0.1 0.19 11.9 0.1 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain zf-UDP PF14569.1 KFM04958.1 - 3.1 7.6 9.6 4.9 6.9 2.2 2.5 1 1 1 2 2 2 0 Zinc-binding RING-finger DZR PF12773.2 KFM04958.1 - 4.1 7.3 11.2 14 5.5 4.4 2.5 1 1 1 2 2 2 0 Double zinc ribbon RMP PF14996.1 KFM04959.1 - 7.5e-47 158.9 5.6 8.2e-47 158.7 3.9 1.0 1 0 0 1 1 1 1 Retinal Maintenance Allantoicase PF03561.10 KFM04959.1 - 0.063 12.7 0.0 0.077 12.4 0.0 1.1 1 0 0 1 1 1 0 Allantoicase repeat UCR_14kD PF02271.11 KFM04960.1 - 1.4e-40 137.2 1.0 1.7e-40 137.0 0.7 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit DDOST_48kD PF03345.9 KFM04960.1 - 0.089 11.3 0.0 0.097 11.1 0.0 1.0 1 0 0 1 1 1 0 Oligosaccharyltransferase 48 kDa subunit beta mTERF PF02536.9 KFM04961.1 - 4.6e-25 87.9 1.2 8.9e-14 50.8 0.1 2.2 1 1 1 2 2 2 2 mTERF HHH_4 PF14490.1 KFM04961.1 - 0.065 12.9 0.1 9 6.1 0.0 3.6 2 1 1 3 3 3 0 Helix-hairpin-helix containing domain PSS PF03034.10 KFM04962.1 - 7.4e-109 363.4 22.9 7.4e-109 363.4 15.8 1.5 2 0 0 2 2 2 1 Phosphatidyl serine synthase Peptidase_C1 PF00112.18 KFM04962.1 - 0.052 13.4 0.1 0.094 12.5 0.1 1.4 1 0 0 1 1 1 0 Papain family cysteine protease DUF2393 PF09624.5 KFM04962.1 - 0.23 10.9 2.8 1 8.9 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2393) DUF2207 PF09972.4 KFM04962.1 - 2.8 6.4 5.7 6.6 5.1 0.5 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Syndecan PF01034.15 KFM04963.1 - 2e-33 113.8 0.0 3.4e-33 113.0 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain Protocadherin PF08374.6 KFM04963.1 - 0.019 14.5 0.7 0.078 12.6 0.0 2.0 1 1 1 2 2 2 0 Protocadherin Herpes_gE PF02480.11 KFM04963.1 - 0.051 11.8 0.0 0.084 11.1 0.0 1.4 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E Plasmodium_Vir PF05795.6 KFM04963.1 - 0.11 11.6 0.1 0.12 11.5 0.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Glycophorin_A PF01102.13 KFM04963.1 - 0.15 11.8 8.7 0.22 11.3 0.3 2.3 1 1 1 2 2 2 0 Glycophorin A MtrF PF09472.5 KFM04963.1 - 0.55 9.5 2.6 0.85 8.8 1.8 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) TGF_beta_GS PF08515.7 KFM04963.1 - 2.8 7.3 4.8 0.6 9.4 0.9 1.7 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif PA PF02225.17 KFM04964.1 - 0.00018 21.1 0.0 0.00032 20.3 0.0 1.4 1 0 0 1 1 1 1 PA domain Peptidase_M28 PF04389.12 KFM04965.1 - 3.4e-18 65.9 0.0 4.5e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KFM04965.1 - 1e-06 28.3 0.0 1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Mtp PF03821.11 KFM04967.1 - 2.9e-29 102.1 10.6 3.4e-29 101.8 7.4 1.0 1 0 0 1 1 1 1 Golgi 4-transmembrane spanning transporter Tetraspannin PF00335.15 KFM04967.1 - 1.4 8.1 13.2 0.023 13.9 1.1 2.1 1 1 1 2 2 2 0 Tetraspanin family DUF3112 PF11309.3 KFM04967.1 - 1.6 8.5 9.3 14 5.3 3.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) zf-DHHC PF01529.15 KFM04967.1 - 3.1 7.1 7.2 6.9 6.0 5.0 1.6 1 1 0 1 1 1 0 DHHC palmitoyltransferase Ribosomal_L7Ae PF01248.21 KFM04968.1 - 3.3e-27 93.8 0.1 3.7e-27 93.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Hydrolase_6 PF13344.1 KFM04968.1 - 0.027 14.3 0.0 0.032 14.1 0.0 1.1 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF2802 PF10975.3 KFM04968.1 - 0.061 13.0 0.1 0.078 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) Ribonuc_L-PSP PF01042.16 KFM04969.1 - 1.6e-38 131.1 0.3 1.8e-38 130.9 0.2 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Con-6 PF10346.4 KFM04969.1 - 0.1 12.0 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 Conidiation protein 6 DUF2482 PF10655.4 KFM04969.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Hypothetical protein of unknown function (DUF2482) POP1 PF06978.6 KFM04970.1 - 3.7e-42 144.1 24.6 7e-26 91.0 3.4 3.2 2 1 1 3 3 3 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 KFM04970.1 - 1.2e-30 105.2 0.2 1.2e-30 105.2 0.1 2.0 2 0 0 2 2 2 1 POPLD (NUC188) domain EF-hand_3 PF09069.6 KFM04970.1 - 0.016 15.2 0.2 1.1 9.3 0.0 3.1 3 0 0 3 3 3 0 EF-hand Mnd1 PF03962.10 KFM04970.1 - 0.044 13.4 3.9 0.09 12.4 0.0 2.5 2 0 0 2 2 2 0 Mnd1 family Mg_trans_NIPA PF05653.9 KFM04971.1 - 2.7e-89 299.1 21.0 3e-89 298.9 14.5 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 KFM04971.1 - 0.00023 21.2 2.8 0.00023 21.2 1.9 2.8 2 1 1 3 3 3 2 EamA-like transporter family DUF872 PF05915.7 KFM04971.1 - 0.078 12.8 0.1 0.078 12.8 0.0 2.8 2 1 2 4 4 4 0 Eukaryotic protein of unknown function (DUF872) Adeno_E3_CR2 PF02439.10 KFM04971.1 - 2.2 7.8 7.5 2.6 7.6 1.4 3.0 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 BTB_2 PF02214.17 KFM04972.1 - 8.7e-32 109.2 0.3 1.6e-30 105.1 0.1 2.5 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans PF00520.26 KFM04972.1 - 4.6e-27 94.5 13.5 5.7e-27 94.2 4.2 2.5 3 0 0 3 3 3 2 Ion transport protein Ion_trans_2 PF07885.11 KFM04972.1 - 8e-13 47.9 3.7 8e-13 47.9 2.6 2.0 2 0 0 2 2 2 1 Ion channel Col_cuticle_N PF01484.12 KFM04972.1 - 9.2 6.0 13.7 8.2 6.2 0.0 3.4 3 0 0 3 3 3 0 Nematode cuticle collagen N-terminal domain Pkinase PF00069.20 KFM04973.1 - 5.1e-71 238.8 0.0 8.7e-71 238.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM04973.1 - 3.2e-53 180.4 1.3 8e-53 179.1 0.0 2.2 3 0 0 3 3 3 1 Protein tyrosine kinase Mst1_SARAH PF11629.3 KFM04973.1 - 4.3e-27 93.6 3.6 1.5e-26 91.9 2.5 2.0 1 0 0 1 1 1 1 C terminal SARAH domain of Mst1 Kinase-like PF14531.1 KFM04973.1 - 0.02 13.8 0.0 1.1 8.1 0.0 2.4 2 0 0 2 2 2 0 Kinase-like NAP PF00956.13 KFM04973.1 - 1.6 7.7 12.5 0.089 11.9 0.4 2.9 3 0 0 3 3 3 0 Nucleosome assembly protein (NAP) zf-C2H2 PF00096.21 KFM04974.1 - 5.5e-05 23.2 3.1 0.00013 22.1 2.1 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM04974.1 - 0.00012 22.1 6.1 0.0018 18.4 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFM04974.1 - 0.015 15.4 1.5 0.03 14.4 1.0 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KFM04974.1 - 0.17 12.3 2.0 0.41 11.0 1.4 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger DUF2616 PF11077.3 KFM04975.1 - 0.12 11.8 2.1 0.16 11.4 1.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2616) COX6C PF02937.10 KFM04976.1 - 2.8e-30 104.0 1.3 3e-30 103.9 0.9 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIc RGS PF00615.14 KFM04977.1 - 2e-09 37.5 0.2 2.6e-09 37.1 0.1 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain HHH_3 PF12836.2 KFM04977.1 - 0.0085 16.0 0.1 0.078 12.9 0.0 2.2 2 1 0 2 2 2 1 Helix-hairpin-helix motif DDE_2 PF02914.10 KFM04977.1 - 0.14 11.6 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage Mu transposase DNA_RNApol_7kD PF03604.8 KFM04978.1 - 5.8e-18 64.0 8.9 8.3e-18 63.5 6.2 1.3 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit A2L_zn_ribbon PF08792.5 KFM04978.1 - 0.0012 18.2 1.0 0.0023 17.3 0.7 1.5 1 0 0 1 1 1 1 A2L zinc ribbon domain HypA PF01155.14 KFM04978.1 - 0.008 15.8 2.6 0.012 15.2 1.8 1.3 1 1 0 1 1 1 1 Hydrogenase expression/synthesis hypA family DZR PF12773.2 KFM04978.1 - 0.0088 15.8 2.6 0.012 15.3 1.8 1.3 1 0 0 1 1 1 1 Double zinc ribbon Cytochrome_C7 PF14522.1 KFM04978.1 - 0.0098 15.5 0.5 0.013 15.1 0.3 1.3 1 0 0 1 1 1 1 Cytochrome c7 zf-CHY PF05495.7 KFM04978.1 - 0.043 13.9 3.3 0.076 13.1 2.3 1.3 1 1 0 1 1 1 0 CHY zinc finger zf-ISL3 PF14690.1 KFM04978.1 - 0.056 13.4 1.3 0.056 13.4 0.9 1.9 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Mu-like_Com PF10122.4 KFM04978.1 - 0.13 11.3 5.7 0.51 9.4 0.0 2.3 1 1 1 2 2 2 0 Mu-like prophage protein Com DUF2082 PF09855.4 KFM04978.1 - 0.14 12.0 0.7 0.14 12.0 0.5 1.7 1 1 1 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zinc_ribbon_5 PF13719.1 KFM04978.1 - 0.22 11.1 2.5 3.3 7.3 1.7 2.2 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KFM04978.1 - 0.23 11.1 2.8 5 6.9 2.0 2.2 1 1 0 1 1 1 0 zinc-ribbon domain Zn_ribbon_recom PF13408.1 KFM04978.1 - 0.72 10.1 5.6 2.6 8.3 2.3 2.0 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain DUF2296 PF10058.4 KFM04978.1 - 0.98 9.2 3.6 5.7 6.7 2.5 2.0 1 1 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) Ribosomal_L44 PF00935.14 KFM04978.1 - 1.1 9.3 5.6 12 6.0 2.2 2.1 1 1 1 2 2 2 0 Ribosomal protein L44 Ribosomal_L37e PF01907.14 KFM04978.1 - 3.3 7.5 5.6 4.9 7.0 3.9 1.4 1 1 0 1 1 1 0 Ribosomal protein L37e RRN7 PF11781.3 KFM04978.1 - 4.3 6.9 6.8 12 5.5 0.3 2.2 1 1 1 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-Sec23_Sec24 PF04810.10 KFM04978.1 - 4.9 6.8 7.0 15 5.2 2.8 2.4 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger IBR PF01485.16 KFM04979.1 - 1.3e-22 79.4 27.3 8.3e-16 57.6 8.2 4.7 4 1 1 5 5 5 2 IBR domain zf-RING_5 PF14634.1 KFM04979.1 - 0.0013 18.3 8.2 0.0013 18.3 5.7 4.3 4 1 0 4 4 4 1 zinc-RING finger domain zf-RING_2 PF13639.1 KFM04979.1 - 0.0024 17.6 9.4 0.0024 17.6 6.5 4.3 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.20 KFM04979.1 - 0.0024 17.4 9.3 0.0024 17.4 6.4 4.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Ank_4 PF13637.1 KFM04981.1 - 1.2e-22 79.8 1.1 2.4e-11 43.8 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 KFM04981.1 - 9.8e-19 67.4 0.1 1.8e-12 47.4 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFM04981.1 - 1.4e-18 65.6 1.8 1.5e-07 30.8 0.1 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 KFM04981.1 - 1.4e-17 63.3 0.8 1.9e-12 46.9 0.2 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM04981.1 - 4.8e-12 44.8 0.2 0.00056 19.9 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat DUF2795 PF11387.3 KFM04981.1 - 0.062 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2795) Dysbindin PF04440.11 KFM04982.1 - 2.5e-39 134.3 8.6 3e-39 134.0 5.9 1.2 1 0 0 1 1 1 1 Dysbindin (Dystrobrevin binding protein 1) Gpi16 PF04113.9 KFM04983.1 - 1.7e-114 382.8 0.5 1.1e-112 376.8 0.3 2.0 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component FDC-SP PF15215.1 KFM04983.1 - 0.038 14.2 0.6 0.38 11.1 0.0 2.6 2 0 0 2 2 2 0 Follicular dendritic cell secreted peptide BC10 PF06726.7 KFM04984.1 - 4.4e-27 93.8 10.2 5.7e-27 93.5 7.1 1.2 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Pkinase_Tyr PF07714.12 KFM04985.1 - 6.7e-94 313.7 0.0 8.2e-94 313.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM04985.1 - 5.8e-51 173.1 0.0 9.5e-51 172.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 KFM04985.1 - 2.2e-16 59.3 0.0 5.6e-16 58.1 0.0 1.7 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.1 KFM04985.1 - 1.3e-05 24.6 0.3 5.1e-05 22.7 0.1 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 KFM04985.1 - 0.00014 21.2 0.2 0.0014 18.0 0.0 2.4 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 KFM04985.1 - 0.0036 16.7 0.1 0.012 15.1 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain APH PF01636.18 KFM04985.1 - 0.0062 16.2 0.0 0.12 12.0 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family UPF0239 PF06783.6 KFM04986.1 - 6.5e-23 80.4 0.0 6.9e-23 80.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0239) DUF4017 PF13209.1 KFM04986.1 - 0.012 15.4 0.3 0.019 14.7 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4017) Hormone_2 PF00123.15 KFM04987.1 - 1.3e-13 50.4 0.1 6.6e-13 48.2 0.0 2.0 2 0 0 2 2 2 1 Peptide hormone Ribophorin_II PF05817.9 KFM04988.1 - 4.1e-267 887.5 6.7 4.6e-267 887.4 4.6 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II EMI PF07546.8 KFM04989.1 - 9.5e-20 70.8 6.2 9.5e-20 70.8 4.3 2.5 3 0 0 3 3 3 1 EMI domain Myosin_tail_1 PF01576.14 KFM04989.1 - 4e-06 24.8 16.8 0.0004 18.2 5.3 2.5 2 0 0 2 2 2 2 Myosin tail Reo_sigmaC PF04582.7 KFM04989.1 - 4.2e-05 22.8 20.6 0.083 12.0 0.1 5.1 2 1 4 6 6 6 3 Reovirus sigma C capsid protein DUF1664 PF07889.7 KFM04989.1 - 0.00036 20.3 17.1 0.025 14.3 0.8 6.1 3 2 1 5 5 5 2 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 KFM04989.1 - 0.0013 18.9 17.3 7.3 6.9 0.9 8.3 6 1 3 9 9 9 1 Nucleopolyhedrovirus P10 protein TPR_MLP1_2 PF07926.7 KFM04989.1 - 0.0025 17.5 23.8 0.35 10.6 2.6 6.0 5 2 0 5 5 5 2 TPR/MLP1/MLP2-like protein CorA PF01544.13 KFM04989.1 - 0.0025 16.8 3.2 0.0025 16.8 2.2 3.7 3 1 1 4 4 4 2 CorA-like Mg2+ transporter protein Spc7 PF08317.6 KFM04989.1 - 0.0034 16.1 22.4 0.041 12.5 0.6 4.6 2 2 2 4 4 4 3 Spc7 kinetochore protein WXG100 PF06013.7 KFM04989.1 - 0.011 15.7 1.2 13 5.8 0.0 5.9 5 3 0 5 5 5 0 Proteins of 100 residues with WXG IncA PF04156.9 KFM04989.1 - 0.014 15.0 25.2 3.9 7.0 0.0 5.8 2 1 2 5 5 5 0 IncA protein Bacillus_HBL PF05791.6 KFM04989.1 - 0.072 12.4 14.3 0.15 11.3 0.4 5.1 4 2 0 5 5 5 0 Bacillus haemolytic enterotoxin (HBL) AF0941-like PF14591.1 KFM04989.1 - 0.089 12.8 5.1 0.97 9.4 0.1 3.6 2 2 0 2 2 2 0 AF0941-like COG2 PF06148.6 KFM04989.1 - 0.37 10.6 19.2 0.33 10.8 0.6 6.0 5 3 2 7 7 6 0 COG (conserved oligomeric Golgi) complex component, COG2 HCMV_UL139 PF12507.3 KFM04989.1 - 0.51 10.5 7.9 5.7 7.1 0.1 4.0 4 1 1 5 5 5 0 Human Cytomegalovirus UL139 protein HALZ PF02183.13 KFM04989.1 - 0.53 10.0 5.8 2.6 7.8 0.1 4.1 4 0 0 4 4 4 0 Homeobox associated leucine zipper FlaC_arch PF05377.6 KFM04989.1 - 1.7 8.6 16.3 15 5.5 0.3 7.7 8 3 2 10 10 9 0 Flagella accessory protein C (FlaC) DUF641 PF04859.7 KFM04989.1 - 2.5 7.8 5.6 6.9 6.4 0.4 3.6 3 2 0 3 3 3 0 Plant protein of unknown function (DUF641) LNS2 PF08235.8 KFM04990.1 - 3.7e-68 228.0 0.0 5.3e-68 227.5 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 KFM04990.1 - 8.7e-49 163.8 0.0 1.5e-48 163.0 0.0 1.4 1 0 0 1 1 1 1 lipin, N-terminal conserved region AF1Q PF15017.1 KFM04990.1 - 0.01 15.6 0.0 0.028 14.3 0.0 1.7 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator PI-PLC-X PF00388.14 KFM04991.1 - 2.8e-65 218.1 0.3 5.6e-65 217.1 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain SH2 PF00017.19 KFM04991.1 - 2.8e-47 158.4 0.1 2e-24 85.2 0.0 3.0 2 0 0 2 2 2 2 SH2 domain PI-PLC-Y PF00387.14 KFM04991.1 - 3.8e-42 142.9 0.1 8.1e-42 141.9 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain SH3_1 PF00018.23 KFM04991.1 - 6e-16 57.5 0.6 1.5e-15 56.2 0.4 1.8 1 0 0 1 1 1 1 SH3 domain C2 PF00168.25 KFM04991.1 - 8.5e-15 54.3 0.0 2.4e-14 52.9 0.0 1.8 1 0 0 1 1 1 1 C2 domain SH3_9 PF14604.1 KFM04991.1 - 9.2e-13 47.5 0.9 1.4e-11 43.7 0.2 2.7 2 0 0 2 2 2 1 Variant SH3 domain PH PF00169.24 KFM04991.1 - 1e-10 41.7 0.1 0.069 13.3 0.0 4.1 4 0 0 4 4 4 3 PH domain SH3_2 PF07653.12 KFM04991.1 - 5.3e-09 35.4 0.1 1.1e-08 34.4 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain EF-hand_like PF09279.6 KFM04991.1 - 1.2e-06 28.3 0.8 3.1e-06 27.0 0.6 1.7 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like GDPD PF03009.12 KFM04991.1 - 9.9e-05 21.9 0.0 0.00033 20.2 0.0 1.8 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Topoisom_I_N PF02919.10 KFM04992.1 - 8.5e-103 342.2 8.0 8.5e-103 342.2 5.5 5.0 4 1 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 KFM04992.1 - 3.2e-97 324.2 4.6 3.2e-97 324.2 3.2 3.2 3 1 1 4 4 4 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 KFM04992.1 - 3.4e-34 116.3 0.5 4.6e-33 112.7 0.3 3.2 1 0 0 1 1 1 1 C-terminal topoisomerase domain Hanta_nucleocap PF00846.13 KFM04992.1 - 0.00038 19.2 7.0 0.00073 18.3 4.9 1.4 1 0 0 1 1 1 1 Hantavirus nucleocapsid protein OB_NTP_bind PF07717.11 KFM04994.1 - 1.1e-27 96.0 0.0 2.3e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KFM04994.1 - 4.8e-25 87.5 0.1 1.3e-24 86.1 0.1 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KFM04994.1 - 5.7e-15 54.9 0.0 1.3e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ABC_tran PF00005.22 KFM04994.1 - 0.00011 22.5 0.2 0.03 14.6 0.0 2.6 1 1 0 2 2 2 1 ABC transporter AAA_22 PF13401.1 KFM04994.1 - 0.0022 18.1 0.1 0.013 15.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain UPF0203 PF05254.7 KFM04994.1 - 0.075 12.8 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) DUF1669 PF07894.7 KFM04995.1 - 3.3e-39 134.7 0.3 2.1e-27 96.0 0.4 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1669) PLDc_2 PF13091.1 KFM04995.1 - 0.0029 17.3 0.0 0.0055 16.4 0.0 1.5 1 0 0 1 1 1 1 PLD-like domain DUF3023 PF11224.3 KFM04995.1 - 0.073 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3023) DUF1669 PF07894.7 KFM04996.1 - 1.6e-57 194.9 0.1 2.5e-57 194.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1669) PLDc_2 PF13091.1 KFM04996.1 - 8e-05 22.3 0.0 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 PLD-like domain Ank PF00023.25 KFM04997.1 - 3.1e-41 137.1 15.3 7.1e-10 38.2 0.4 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.2 KFM04997.1 - 6.9e-41 138.4 14.4 9.4e-19 67.5 1.9 2.9 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFM04997.1 - 3.5e-33 113.3 9.8 1.4e-14 54.1 0.4 5.8 3 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM04997.1 - 1e-30 105.0 15.5 1.4e-11 44.1 2.0 5.3 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM04997.1 - 2.4e-22 76.7 11.5 1.2e-05 25.0 0.1 5.5 5 0 0 5 5 5 4 Ankyrin repeat RepB-RCR_reg PF10723.4 KFM04997.1 - 0.0085 15.7 3.0 0.0085 15.7 2.1 2.6 3 0 0 3 3 3 1 Replication regulatory protein RepB APG6 PF04111.7 KFM04997.1 - 0.14 11.1 5.7 0.3 10.1 4.0 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4337 PF14235.1 KFM04997.1 - 0.21 11.4 3.9 0.47 10.2 2.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Actin PF00022.14 KFM04998.1 - 4.8e-43 147.0 0.0 2.2e-41 141.5 0.0 2.1 1 1 0 1 1 1 1 Actin DUF1542 PF07564.6 KFM04998.1 - 0.054 13.5 1.6 0.77 9.8 0.1 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) PDDEXK_1 PF12705.2 KFM04998.1 - 0.8 9.0 5.9 1.2 8.4 3.7 1.4 1 1 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Aa_trans PF01490.13 KFM04999.1 - 2.3e-92 309.6 19.9 2.6e-92 309.4 13.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Pkinase PF00069.20 KFM05000.1 - 6.2e-71 238.5 0.0 7.1e-71 238.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM05000.1 - 3.7e-35 121.2 0.0 4.5e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KFM05000.1 - 1.1e-05 25.8 0.2 2e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KFM05000.1 - 5e-05 22.4 0.0 0.00014 20.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFM05000.1 - 0.00059 18.9 0.0 0.00094 18.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ABC_transp_aux PF09822.4 KFM05001.1 - 1.2e-09 38.0 0.0 7.8e-08 32.0 0.0 2.2 2 0 0 2 2 2 2 ABC-type uncharacterized transport system DUF4159 PF13709.1 KFM05001.1 - 0.03 13.4 0.1 0.13 11.3 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4159) Cmyb_C PF09316.5 KFM05003.1 - 1.1e-63 213.8 5.9 2.8e-63 212.5 4.1 1.7 1 0 0 1 1 1 1 C-myb, C-terminal Myb_DNA-binding PF00249.26 KFM05003.1 - 4.2e-47 157.9 16.6 3.3e-16 59.0 2.7 3.6 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFM05003.1 - 5.8e-47 157.6 15.2 2.2e-20 72.5 0.6 3.5 1 1 2 3 3 3 3 Myb-like DNA-binding domain Sigma70_r4_2 PF08281.7 KFM05003.1 - 0.0011 18.4 0.0 0.0025 17.2 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Rap1_C PF11626.3 KFM05003.1 - 0.1 12.5 7.7 13 5.7 2.5 3.5 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain BTG PF07742.7 KFM05004.1 - 1.5e-30 105.1 0.0 2.9e-30 104.2 0.0 1.5 2 0 0 2 2 2 1 BTG family Tropomyosin_1 PF12718.2 KFM05005.1 - 0.041 13.7 18.1 0.086 12.6 12.5 1.4 1 0 0 1 1 1 0 Tropomyosin like Fib_alpha PF08702.5 KFM05005.1 - 1.4 8.9 12.4 3.9 7.5 8.6 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF342 PF03961.8 KFM05005.1 - 3.8 5.8 10.3 6.1 5.1 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 KFM05005.1 - 9.5 5.7 20.8 6.7 6.2 13.0 1.8 2 0 0 2 2 2 0 IncA protein Shisa PF13908.1 KFM05006.1 - 8.4e-28 97.7 12.0 8.4e-28 97.7 8.3 1.4 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator DUF3609 PF12259.3 KFM05006.1 - 0.045 12.4 0.2 0.057 12.0 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) IncA PF04156.9 KFM05006.1 - 0.21 11.1 0.8 0.23 11.0 0.6 1.1 1 0 0 1 1 1 0 IncA protein Corona_S2 PF01601.11 KFM05006.1 - 5.4 4.9 5.7 6.4 4.7 3.9 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein DUF1394 PF07159.7 KFM05007.1 - 6.5e-163 541.0 1.0 7.3e-163 540.8 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) WASH-7_N PF14745.1 KFM05007.1 - 0.0046 15.2 0.6 0.024 12.8 0.0 2.1 1 1 1 3 3 3 1 WASH complex subunit 7, N-terminal Endonuc-BglII PF09195.6 KFM05007.1 - 0.055 12.9 0.0 0.1 12.0 0.0 1.4 1 1 0 1 1 1 0 Restriction endonuclease BglII DUF2284 PF10050.4 KFM05007.1 - 0.081 12.5 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) NUDIX_4 PF14815.1 KFM05007.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.5 1 1 0 1 1 1 0 NUDIX domain DEAD PF00270.24 KFM05009.1 - 2.1e-73 245.3 0.0 1.2e-72 242.9 0.0 2.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase SPRY PF00622.23 KFM05009.1 - 1.3e-25 89.9 0.1 2.5e-25 88.9 0.1 1.5 1 0 0 1 1 1 1 SPRY domain Helicase_C PF00271.26 KFM05009.1 - 2.4e-23 81.7 0.1 5.5e-23 80.6 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 KFM05009.1 - 0.0012 18.0 0.0 0.0059 15.7 0.0 2.0 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit LRAT PF04970.8 KFM05011.1 - 5.8e-09 35.9 0.1 3.2e-07 30.3 0.1 2.5 1 1 0 1 1 1 1 Lecithin retinol acyltransferase NLPC_P60 PF00877.14 KFM05011.1 - 0.003 17.3 0.0 0.011 15.5 0.0 1.9 1 1 0 1 1 1 1 NlpC/P60 family RVT_1 PF00078.22 KFM05013.1 - 4.7e-16 58.7 0.0 8e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1725 PF08333.6 KFM05013.1 - 1.4 8.3 3.7 15 5.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1725) Pkinase PF00069.20 KFM05014.1 - 1e-35 123.1 0.0 1.4e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM05014.1 - 6.5e-19 68.0 0.0 8.9e-19 67.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM05014.1 - 4.7e-06 25.7 0.0 1.3e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFM05014.1 - 0.077 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LNS2 PF08235.8 KFM05015.1 - 1.4e-70 235.9 0.0 2.2e-70 235.2 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 KFM05015.1 - 4.8e-50 167.8 0.0 9.9e-50 166.8 0.0 1.6 1 0 0 1 1 1 1 lipin, N-terminal conserved region BLVR PF06375.6 KFM05015.1 - 0.0019 18.0 2.6 0.0019 18.0 1.8 2.2 2 0 0 2 2 2 1 Bovine leukaemia virus receptor (BLVR) E2F_TDP PF02319.15 KFM05017.1 - 1e-22 79.4 0.4 2e-22 78.5 0.1 1.7 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain Med4 PF10018.4 KFM05017.1 - 0.0022 17.4 0.1 0.0035 16.7 0.1 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 TrmB PF01978.14 KFM05017.1 - 0.041 13.5 0.0 0.079 12.6 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB FAD_binding_1 PF00667.15 KFM05017.1 - 0.046 13.1 0.1 0.29 10.5 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain HrpB7 PF09486.5 KFM05017.1 - 0.13 12.2 0.1 0.19 11.6 0.1 1.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) LLC1 PF14945.1 KFM05019.1 - 3.9e-06 27.1 5.7 4.1e-05 23.8 2.1 2.1 1 1 1 2 2 2 2 Normal lung function maintenance, Low in Lung Cancer 1 protein Thioredoxin PF00085.15 KFM05020.1 - 2e-66 220.1 0.0 3e-32 110.3 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 KFM05020.1 - 5.6e-14 52.2 1.0 8e-05 22.8 0.0 4.3 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KFM05020.1 - 1.4e-10 41.1 0.0 0.00024 21.1 0.0 3.2 2 2 1 3 3 3 2 Thioredoxin-like Thioredoxin_6 PF13848.1 KFM05020.1 - 1.5e-09 37.9 0.0 0.061 13.1 0.0 3.2 3 0 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KFM05020.1 - 1.3e-08 34.7 0.0 0.0016 18.4 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_3 PF13192.1 KFM05020.1 - 5.7e-05 22.8 0.0 0.11 12.3 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin domain AhpC-TSA PF00578.16 KFM05020.1 - 0.0033 17.0 0.0 2.4 7.8 0.0 2.3 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_4 PF13462.1 KFM05020.1 - 0.0081 16.1 0.0 1.2 9.0 0.0 2.8 2 1 1 3 3 3 1 Thioredoxin Thioredoxin_9 PF14595.1 KFM05020.1 - 0.0088 15.6 0.1 0.27 10.7 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin HyaE PF07449.6 KFM05020.1 - 0.02 14.8 0.0 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE FAD_binding_7 PF03441.9 KFM05020.1 - 0.098 11.8 0.1 0.73 8.9 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain of DNA photolyase Redoxin PF08534.5 KFM05020.1 - 0.13 11.7 0.1 4.5 6.7 0.0 2.3 2 0 0 2 2 2 0 Redoxin NUC153 PF08159.7 KFM05021.1 - 3.6e-14 52.0 1.0 8.4e-14 50.8 0.7 1.7 1 0 0 1 1 1 1 NUC153 domain Ribosomal_S16 PF00886.14 KFM05021.1 - 0.045 13.4 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 Ribosomal protein S16 Orn_Arg_deC_N PF02784.11 KFM05022.1 - 1.4e-85 286.4 0.0 1.9e-85 286.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 KFM05022.1 - 9.9e-33 112.3 0.1 2.1e-32 111.2 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.19 KFM05022.1 - 0.0094 15.2 0.0 0.022 14.0 0.0 1.5 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Cas6 PF09559.5 KFM05022.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Cas6 Crispr EF-hand_1 PF00036.27 KFM05024.1 - 3.6e-27 91.5 5.5 2.1e-07 29.7 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KFM05024.1 - 8.4e-27 93.1 1.0 2.3e-16 59.6 0.0 2.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 KFM05024.1 - 5.2e-23 79.2 3.1 2.3e-07 29.8 0.2 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 KFM05024.1 - 1.4e-22 77.4 0.9 2.5e-06 26.8 0.1 4.4 4 1 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 KFM05024.1 - 2.6e-19 68.5 4.3 1.7e-08 33.9 0.1 4.1 2 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFM05024.1 - 1.4e-07 31.5 0.0 0.00034 20.6 0.0 3.0 2 2 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFM05024.1 - 4e-06 26.5 0.7 0.15 11.8 0.0 3.4 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 KFM05024.1 - 0.008 15.8 2.3 2.8 7.6 0.0 3.2 4 0 0 4 4 4 2 EF hand CP2 PF04516.10 KFM05026.1 - 6e-85 284.0 3.1 9e-85 283.4 2.2 1.2 1 0 0 1 1 1 1 CP2 transcription factor RRN7 PF11781.3 KFM05027.1 - 4.1e-10 38.9 4.4 1.2e-09 37.5 3.0 1.9 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 14-3-3 PF00244.15 KFM05029.1 - 2.4e-111 370.4 6.1 2.7e-111 370.2 4.3 1.0 1 0 0 1 1 1 1 14-3-3 protein PDDEXK_4 PF14281.1 KFM05029.1 - 0.036 13.9 0.1 0.069 12.9 0.1 1.5 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Clathrin-link PF09268.5 KFM05029.1 - 0.059 12.4 0.0 0.14 11.2 0.0 1.7 1 0 0 1 1 1 0 Clathrin, heavy-chain linker FliM PF02154.10 KFM05029.1 - 0.078 12.6 0.1 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Flagellar motor switch protein FliM Reprolysin_5 PF13688.1 KFM05030.1 - 6.8e-36 124.0 0.0 1.4e-35 123.0 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 KFM05030.1 - 1.7e-28 99.8 0.1 3.1e-28 98.9 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFM05030.1 - 1.7e-22 79.9 0.2 2.5e-22 79.4 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 KFM05030.1 - 8.6e-15 54.7 24.8 8.6e-15 54.7 17.2 3.2 2 1 1 3 3 3 1 Disintegrin Reprolysin PF01421.14 KFM05030.1 - 4.7e-12 45.9 0.3 1.7e-06 27.7 0.1 3.5 2 1 1 3 3 3 2 Reprolysin (M12B) family zinc metalloprotease Reprolysin_3 PF13582.1 KFM05030.1 - 2.9e-11 43.9 0.1 6.4e-11 42.8 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.14 KFM05030.1 - 1.3e-09 37.9 0.1 2.2e-09 37.1 0.1 1.3 1 0 0 1 1 1 1 Reprolysin family propeptide Lipase_GDSL PF00657.17 KFM05031.1 - 3.8e-24 85.8 0.0 4.8e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KFM05031.1 - 1.1e-21 77.7 0.0 1.3e-21 77.5 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family CPSF73-100_C PF11718.3 KFM05032.1 - 2e-61 207.1 0.2 3.3e-61 206.3 0.1 1.4 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 KFM05032.1 - 9.7e-33 112.7 0.0 2.4e-32 111.4 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 KFM05032.1 - 1e-15 57.8 0.3 1.8e-15 57.1 0.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 KFM05032.1 - 3.5e-13 49.1 0.0 7.7e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 KFM05032.1 - 4.2e-11 42.7 2.3 2.8e-10 40.0 0.6 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KFM05032.1 - 1e-06 28.5 0.1 2e-05 24.3 0.0 2.8 2 1 1 3 3 3 2 Beta-lactamase superfamily domain ICAP-1_inte_bdg PF10480.4 KFM05033.1 - 1.2e-126 420.2 6.6 1.3e-126 420.1 4.6 1.0 1 0 0 1 1 1 1 Beta-1 integrin binding protein PID PF00640.18 KFM05033.1 - 0.00024 21.0 0.0 0.00057 19.8 0.0 1.7 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) YCII PF03795.9 KFM05033.1 - 0.09 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 YCII-related domain ArfGap PF01412.13 KFM05034.1 - 6.4e-34 116.2 0.5 2.1e-33 114.6 0.0 2.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Ank_2 PF12796.2 KFM05034.1 - 1.7e-18 66.7 6.5 2.9e-10 40.3 0.4 2.5 2 1 1 3 3 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFM05034.1 - 2.5e-11 42.8 0.7 0.00012 21.7 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat SH3_9 PF14604.1 KFM05034.1 - 2.2e-10 39.9 0.1 4.3e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 KFM05034.1 - 2.9e-09 37.0 0.4 9.8e-09 35.3 0.3 2.0 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.23 KFM05034.1 - 5.7e-09 35.2 1.1 1.4e-08 33.9 0.1 2.2 2 0 0 2 2 2 1 SH3 domain Ank_4 PF13637.1 KFM05034.1 - 1.3e-08 35.0 1.2 0.0002 21.7 0.0 2.9 2 1 2 4 4 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM05034.1 - 3.6e-08 33.3 0.2 1.5e-06 28.2 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) SH3_2 PF07653.12 KFM05034.1 - 3.4e-07 29.6 0.2 8e-07 28.4 0.1 1.7 2 0 0 2 2 2 1 Variant SH3 domain Ank_3 PF13606.1 KFM05034.1 - 5.5e-05 23.0 0.8 1.4 9.3 0.0 4.0 4 0 0 4 4 3 2 Ankyrin repeat PH_9 PF15410.1 KFM05034.1 - 0.0056 16.8 0.2 1.6 8.9 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain MIF4G PF02854.14 KFM05034.1 - 0.054 12.9 3.8 0.11 11.8 2.7 1.4 1 0 0 1 1 1 0 MIF4G domain GLTP PF08718.6 KFM05034.1 - 0.23 11.5 3.1 0.28 11.2 0.8 2.0 1 1 1 2 2 2 0 Glycolipid transfer protein (GLTP) DUF4404 PF14357.1 KFM05034.1 - 2.7 8.4 7.7 0.97 9.8 2.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) MBOAT PF03062.14 KFM05035.1 - 9.3e-34 116.9 9.8 9.3e-34 116.9 6.8 2.2 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family DPM3 PF08285.6 KFM05035.1 - 0.15 11.9 2.8 0.78 9.6 1.9 2.2 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) KAP_NTPase PF07693.9 KFM05036.1 - 1.4e-105 352.8 0.1 2e-105 352.3 0.1 1.2 1 0 0 1 1 1 1 KAP family P-loop domain Ank_2 PF12796.2 KFM05036.1 - 3.5e-91 299.6 3.5 2.2e-18 66.3 0.0 5.7 3 2 1 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KFM05036.1 - 2.4e-88 285.8 2.1 1e-09 37.6 0.0 12.6 12 0 0 12 12 12 11 Ankyrin repeat Ank_5 PF13857.1 KFM05036.1 - 4.4e-69 226.9 7.1 2.7e-13 49.6 0.1 10.5 2 1 8 10 10 10 10 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFM05036.1 - 9.4e-67 220.3 5.9 1.3e-10 41.4 0.0 9.6 2 2 8 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM05036.1 - 8.1e-57 183.4 2.1 1.5e-06 27.8 0.0 12.6 12 0 0 12 12 12 10 Ankyrin repeat NACHT PF05729.7 KFM05036.1 - 0.00052 19.7 0.1 0.062 12.9 0.0 3.0 3 0 0 3 3 3 1 NACHT domain SAM_1 PF00536.25 KFM05036.1 - 0.0032 17.6 0.0 0.016 15.3 0.0 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DUF2207 PF09972.4 KFM05036.1 - 2.5 6.5 5.9 2.3 6.7 0.1 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) HLH PF00010.21 KFM05037.1 - 6.8e-14 51.2 0.4 1.1e-13 50.6 0.3 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RVT_1 PF00078.22 KFM05038.1 - 1.3e-14 54.1 0.0 1.7e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Arg_repressor PF01316.16 KFM05038.1 - 0.022 14.2 0.1 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain IBR PF01485.16 KFM05039.1 - 7.4e-19 67.3 27.4 1e-12 47.7 8.1 4.7 4 1 1 5 5 5 2 IBR domain zf-RING_2 PF13639.1 KFM05039.1 - 0.013 15.3 7.0 0.013 15.3 4.9 4.0 3 1 1 4 4 4 0 Ring finger domain Radical_SAM PF04055.16 KFM05040.1 - 4.4e-07 30.2 0.0 1.4e-06 28.6 0.0 1.9 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 KFM05040.1 - 0.00032 20.6 0.0 0.0016 18.4 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 KFM05040.1 - 0.00078 19.5 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Thymidylate_kin PF02223.12 KFM05041.1 - 2.6e-09 36.7 0.2 1.3e-08 34.4 0.1 2.0 1 1 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.1 KFM05041.1 - 0.0005 19.9 0.0 0.00061 19.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain PPK2 PF03976.9 KFM05041.1 - 0.011 15.0 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) AAA_28 PF13521.1 KFM05041.1 - 0.032 14.2 0.0 0.043 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KFM05041.1 - 0.057 13.4 0.0 0.06 13.3 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 KFM05041.1 - 0.086 13.6 0.0 0.11 13.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain HMG_box PF00505.14 KFM05042.1 - 5.9e-26 90.5 3.2 1.1e-25 89.6 2.2 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFM05042.1 - 6.2e-09 36.0 0.6 1.6e-08 34.8 0.4 1.7 1 0 0 1 1 1 1 HMG-box domain Roughex PF06020.6 KFM05042.1 - 0.047 12.3 0.2 0.065 11.8 0.1 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Lectin_C PF00059.16 KFM05043.1 - 5.2e-16 59.1 0.1 8e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Lectin C-type domain Collagen PF01391.13 KFM05043.1 - 9.4e-15 53.9 53.2 8.5e-09 34.8 16.1 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Ribosomal_S7e PF01251.13 KFM05044.1 - 3.8e-92 306.9 4.3 4.2e-92 306.8 3.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e RNase_H PF00075.19 KFM05045.1 - 6.4e-36 123.6 0.0 8.7e-36 123.1 0.0 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 KFM05045.1 - 0.00077 19.2 0.0 0.017 14.8 0.0 2.3 2 0 0 2 2 2 1 Reverse transcriptase-like TPR_11 PF13414.1 KFM05047.1 - 2.5e-16 59.0 0.0 3.3e-08 33.0 0.0 2.6 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KFM05047.1 - 8.8e-14 50.2 0.0 0.0032 17.2 0.0 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 KFM05047.1 - 7.9e-12 44.2 0.0 0.0019 17.7 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFM05047.1 - 1.4e-10 41.3 0.2 2.8e-05 24.3 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFM05047.1 - 7.4e-09 36.0 0.0 0.0044 17.6 0.0 2.9 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFM05047.1 - 1.8e-08 34.2 0.8 0.00082 19.2 0.0 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.1 KFM05047.1 - 6e-06 26.3 0.2 0.0073 16.6 0.0 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFM05047.1 - 9.6e-06 25.7 0.0 7.7 7.4 0.0 5.0 3 2 2 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 KFM05047.1 - 0.0002 21.4 3.2 0.064 13.3 0.1 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 Coatomer_E PF04733.9 KFM05047.1 - 0.00029 20.1 0.2 0.00069 18.8 0.1 1.6 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_17 PF13431.1 KFM05047.1 - 0.0019 18.2 0.4 0.83 10.0 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFM05047.1 - 0.0061 16.2 0.0 1 9.3 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFM05047.1 - 0.0067 16.1 0.0 3.4 7.6 0.0 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat WD40 PF00400.27 KFM05048.1 - 1.8e-22 78.3 8.3 5e-07 29.3 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat YmzC PF14157.1 KFM05048.1 - 0.12 12.2 0.0 0.12 12.2 0.0 2.8 3 0 0 3 3 3 0 YmzC-like protein An_peroxidase PF03098.10 KFM05051.1 - 9.9e-183 608.3 0.0 1.3e-182 607.9 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase I-set PF07679.11 KFM05051.1 - 1.1e-86 284.7 0.4 1e-20 73.3 0.0 4.4 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM05051.1 - 3.5e-54 180.8 4.5 8.5e-14 51.4 0.0 4.5 4 0 0 4 4 4 4 Immunoglobulin domain LRR_8 PF13855.1 KFM05051.1 - 9e-52 172.6 31.2 2.1e-17 62.6 2.3 3.8 1 1 3 4 4 4 4 Leucine rich repeat Ig_3 PF13927.1 KFM05051.1 - 7.1e-41 138.5 5.3 3.6e-11 43.3 0.5 4.7 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.20 KFM05051.1 - 3.5e-34 116.7 1.8 9.5e-13 48.0 0.1 4.8 4 0 0 4 4 4 4 Immunoglobulin domain V-set PF07686.12 KFM05051.1 - 1.2e-31 108.9 0.8 9.2e-08 31.9 0.0 5.3 4 1 0 4 4 4 4 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM05051.1 - 3.1e-18 65.4 2.9 0.0011 18.7 0.0 4.6 4 0 0 4 4 4 4 CD80-like C2-set immunoglobulin domain LRR_4 PF12799.2 KFM05051.1 - 3.4e-17 61.6 15.9 1e-07 31.3 0.1 4.7 5 1 0 6 6 5 3 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFM05051.1 - 6.3e-11 42.0 1.9 2.7e-09 36.8 0.0 2.7 2 0 0 2 2 2 1 Leucine rich repeats (6 copies) VWC PF00093.13 KFM05051.1 - 3.8e-09 36.5 18.8 3.8e-09 36.5 13.1 2.9 3 0 0 3 3 2 1 von Willebrand factor type C domain LRR_1 PF00560.28 KFM05051.1 - 1.8e-07 30.2 14.8 2.5 8.4 0.1 7.0 6 0 0 6 6 5 4 Leucine Rich Repeat Sp38 PF07354.7 KFM05051.1 - 1.3e-06 27.2 0.0 0.054 12.1 0.0 3.2 3 0 0 3 3 3 2 Zona-pellucida-binding protein (Sp38) LRR_9 PF14580.1 KFM05051.1 - 1.1e-05 25.0 0.8 0.00084 18.9 0.1 2.3 1 1 1 2 2 2 1 Leucine-rich repeat PSP94 PF05825.6 KFM05051.1 - 0.0016 18.6 9.0 0.0047 17.1 6.3 1.7 1 0 0 1 1 1 1 Beta-microseminoprotein (PSP-94) LRR_7 PF13504.1 KFM05051.1 - 0.019 15.0 10.4 39 5.0 0.0 6.0 5 0 0 5 5 5 0 Leucine rich repeat DUF3673 PF12425.3 KFM05051.1 - 0.099 12.5 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3673) PA28_beta PF02252.13 KFM05051.1 - 0.15 11.5 0.1 0.97 8.8 0.1 2.1 2 0 0 2 2 2 0 Proteasome activator pa28 beta subunit UPF0220 PF05255.6 KFM05051.1 - 0.38 9.9 0.0 0.68 9.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0220) LRR_6 PF13516.1 KFM05051.1 - 0.41 10.8 6.9 1.1e+02 3.3 0.0 5.7 6 1 1 7 7 4 0 Leucine Rich repeat An_peroxidase PF03098.10 KFM05052.1 - 1e-159 532.3 0.0 1.3e-159 532.0 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase EGF_CA PF07645.10 KFM05052.1 - 1.9e-07 30.9 3.3 1.9e-07 30.9 2.3 2.5 2 0 0 2 2 2 1 Calcium-binding EGF domain Sushi PF00084.15 KFM05052.1 - 4e-05 23.8 4.4 4e-05 23.8 3.0 2.5 2 0 0 2 2 2 1 Sushi domain (SCR repeat) FXa_inhibition PF14670.1 KFM05052.1 - 0.0025 17.9 3.7 0.0025 17.9 2.6 2.9 3 0 0 3 3 3 1 Coagulation Factor Xa inhibitory site EGF_3 PF12947.2 KFM05052.1 - 0.0037 17.1 3.4 0.0037 17.1 2.3 2.3 2 0 0 2 2 2 1 EGF domain cEGF PF12662.2 KFM05052.1 - 0.22 11.2 3.6 3.9 7.2 0.2 3.4 3 1 0 3 3 3 0 Complement Clr-like EGF-like PDZ PF00595.19 KFM05053.1 - 2.8e-16 59.4 0.9 4.6e-16 58.7 0.6 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM05053.1 - 3.4e-05 23.6 0.2 7.8e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PH PF00169.24 KFM05053.1 - 0.019 15.1 0.0 4.4 7.5 0.0 2.8 2 1 0 2 2 2 0 PH domain Tricorn_PDZ PF14685.1 KFM05053.1 - 0.025 14.3 0.4 0.22 11.3 0.0 2.4 2 0 0 2 2 2 0 Tricorn protease PDZ domain TMEM18 PF14770.1 KFM05056.1 - 1.1e-43 147.6 6.8 1.3e-43 147.4 4.7 1.0 1 0 0 1 1 1 1 Transmembrane protein 18 7TM_GPCR_Sri PF10327.4 KFM05056.1 - 0.0034 16.4 4.7 0.0037 16.2 3.2 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sri PLD_C PF12357.3 KFM05056.1 - 0.1 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Phospholipase D C terminal COPI_assoc PF08507.5 KFM05056.1 - 3.5 7.3 8.3 0.88 9.2 2.4 2.0 1 1 1 2 2 2 0 COPI associated protein FAM150 PF15129.1 KFM05058.1 - 1.4e-60 202.5 0.7 1.7e-60 202.3 0.5 1.1 1 0 0 1 1 1 1 FAM150 family LMWPc PF01451.16 KFM05059.1 - 3.5e-41 140.7 0.1 3.9e-41 140.6 0.1 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase DUF500 PF04366.7 KFM05061.1 - 2.9e-42 143.0 0.0 4.4e-42 142.4 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 KFM05061.1 - 8.3e-16 57.1 0.1 1.9e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFM05061.1 - 1.5e-13 50.0 0.0 2.5e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFM05061.1 - 1.4e-11 43.7 0.0 2.4e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain RRM_1 PF00076.17 KFM05062.1 - 9.6e-10 37.9 0.0 2.5e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM05062.1 - 1.4e-05 24.9 0.0 3.2e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFM05062.1 - 0.0093 15.7 0.1 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.1 KFM05062.1 - 0.059 13.2 0.3 0.21 11.4 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TetR_C_7 PF14246.1 KFM05062.1 - 0.13 12.5 0.7 12 6.2 0.0 3.0 2 0 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal region TBPIP PF07106.8 KFM05062.1 - 0.78 9.2 21.3 0.063 12.8 9.6 2.5 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4361 PF14274.1 KFM05063.1 - 0.13 11.9 0.1 0.13 11.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4361) PTPlike_phytase PF14566.1 KFM05063.1 - 1.3 9.0 16.3 0.35 10.9 0.5 3.0 2 1 0 2 2 2 0 Inositol hexakisphosphate TNF PF00229.13 KFM05064.1 - 9.9e-30 102.7 0.9 1.5e-29 102.1 0.6 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family RII_binding_1 PF10522.4 KFM05065.1 - 0.39 11.0 1.8 19 5.8 0.0 4.2 4 0 0 4 4 4 0 RII binding domain DAGK_acc PF00609.14 KFM05066.1 - 3.9e-54 183.1 0.0 7.9e-54 182.1 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 KFM05066.1 - 6e-30 103.3 0.0 1.8e-29 101.8 0.0 1.9 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.17 KFM05066.1 - 1.6e-19 69.3 25.7 1e-10 41.1 3.9 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.24 KFM05066.1 - 2.4e-18 66.2 1.1 7.5e-18 64.6 0.8 1.9 1 0 0 1 1 1 1 PH domain SAM_2 PF07647.12 KFM05066.1 - 2e-17 62.7 0.2 6.6e-17 61.1 0.1 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFM05066.1 - 7.5e-16 58.0 0.5 1.7e-15 56.9 0.3 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.1 KFM05066.1 - 7e-06 26.2 6.3 1.9e-05 24.8 1.0 3.4 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 KFM05066.1 - 0.00015 21.7 0.3 0.00032 20.7 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain C1_3 PF07649.7 KFM05066.1 - 0.001 19.0 2.7 0.001 19.0 1.8 2.8 2 0 0 2 2 2 1 C1-like domain C1_2 PF03107.11 KFM05066.1 - 0.015 15.4 4.5 0.015 15.4 3.1 2.7 3 0 0 3 3 3 0 C1 domain DUF883 PF05957.8 KFM05066.1 - 0.032 14.6 1.3 0.1 12.9 0.9 1.9 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Mcp5_PH PF12814.2 KFM05066.1 - 0.034 14.0 0.0 0.1 12.5 0.0 1.8 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology AAA_5 PF07728.9 KFM05069.1 - 5.1e-101 334.0 0.0 1.9e-39 134.5 0.0 3.6 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) VWA_2 PF13519.1 KFM05069.1 - 3.8e-11 43.3 0.0 8.2e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain AAA_16 PF13191.1 KFM05069.1 - 2.3e-08 34.2 2.3 0.22 11.4 0.0 5.9 4 1 0 5 5 5 2 AAA ATPase domain AAA PF00004.24 KFM05069.1 - 8.3e-06 26.0 0.2 0.02 15.0 0.0 3.8 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KFM05069.1 - 9.1e-06 25.5 0.2 0.059 13.2 0.0 3.4 4 0 0 4 4 3 2 AAA domain AAA_3 PF07726.6 KFM05069.1 - 4.9e-05 22.9 0.0 0.0075 15.8 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFM05069.1 - 0.00016 21.8 0.2 0.81 9.8 0.0 4.6 2 2 1 3 3 3 1 AAA domain VWA PF00092.23 KFM05069.1 - 0.00073 19.2 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Mg_chelatase PF01078.16 KFM05069.1 - 0.001 18.2 0.3 3.1 6.9 0.0 3.6 4 0 0 4 4 4 2 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 KFM05069.1 - 0.0041 17.9 0.0 0.061 14.1 0.0 3.1 3 0 0 3 3 2 1 AAA domain CbbQ_C PF08406.5 KFM05069.1 - 0.0043 17.0 0.0 3.3 7.7 0.0 2.6 2 0 0 2 2 2 2 CbbQ/NirQ/NorQ C-terminal AAA_2 PF07724.9 KFM05069.1 - 0.0053 16.6 0.0 2 8.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_28 PF13521.1 KFM05069.1 - 0.025 14.5 0.0 0.064 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KFM05069.1 - 0.063 13.5 0.0 0.37 11.0 0.0 2.3 2 0 0 2 2 1 0 AAA domain Miro PF08477.8 KFM05069.1 - 0.075 13.5 0.0 2.1 8.8 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein ATP-synt_ab PF00006.20 KFM05069.1 - 0.15 11.5 0.0 1.8 7.9 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.17 KFM05069.1 - 0.18 11.9 0.0 1.5 9.0 0.0 2.4 2 0 0 2 2 2 0 RNA helicase NARP1 PF12569.3 KFM05071.1 - 8.8e-213 707.7 20.7 8.8e-213 707.7 14.3 2.1 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 KFM05071.1 - 2.8e-17 62.1 22.3 4.4e-07 29.4 0.3 7.8 5 1 1 7 7 7 4 TPR repeat TPR_2 PF07719.12 KFM05071.1 - 1.1e-15 56.2 22.5 4.2e-05 23.1 0.1 8.2 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 KFM05071.1 - 4e-13 48.7 2.1 0.15 12.7 0.0 7.9 6 2 2 8 8 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFM05071.1 - 1.6e-12 47.5 11.3 0.01 16.1 0.1 6.1 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 KFM05071.1 - 4.5e-11 43.0 14.5 0.00057 20.4 0.1 6.5 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFM05071.1 - 2.9e-10 39.9 16.1 0.039 13.9 0.1 7.3 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFM05071.1 - 3e-09 36.0 34.9 1.6e-05 24.3 0.4 8.9 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFM05071.1 - 5.6e-08 32.0 21.8 0.0012 18.4 0.1 7.5 8 0 0 8 8 8 2 Tetratricopeptide repeat Apc3 PF12895.2 KFM05071.1 - 3.4e-07 30.3 24.0 0.00055 20.0 0.6 6.9 4 2 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 KFM05071.1 - 4.4e-06 25.9 0.2 4.4e-06 25.9 0.1 3.6 5 1 0 5 5 5 1 Tetratricopeptide repeat MIT PF04212.13 KFM05071.1 - 0.0011 18.8 4.3 0.02 14.7 0.0 4.1 3 2 1 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_17 PF13431.1 KFM05071.1 - 0.0018 18.3 18.8 1.8 8.9 0.0 8.3 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFM05071.1 - 0.0025 17.4 17.0 0.011 15.5 0.1 7.2 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFM05071.1 - 0.0063 16.3 8.5 0.28 11.0 0.3 5.3 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFM05071.1 - 0.02 15.3 10.7 19 5.9 0.1 6.5 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 KFM05071.1 - 0.025 14.4 5.4 26 4.8 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 KFM05071.1 - 0.031 14.6 0.0 1.2e+02 3.5 0.0 4.5 6 0 0 6 6 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KFM05071.1 - 0.089 12.6 19.8 8 6.4 0.1 6.7 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.7 KFM05071.1 - 2.8 7.8 18.8 0.43 10.4 0.1 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat RF-1 PF00472.15 KFM05072.1 - 1.3e-39 134.4 2.4 3.6e-39 133.0 1.6 1.8 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 KFM05072.1 - 1.1e-29 102.4 0.1 1.1e-29 102.4 0.1 3.1 3 1 1 4 4 4 1 PCRF domain MIR PF02815.14 KFM05072.1 - 0.034 13.6 0.2 0.58 9.6 0.0 2.3 2 0 0 2 2 2 0 MIR domain HisKA PF00512.20 KFM05072.1 - 0.45 10.5 7.7 0.59 10.1 0.7 3.5 3 1 0 3 3 3 0 His Kinase A (phospho-acceptor) domain zf-C4pol PF14260.1 KFM05072.1 - 0.77 9.8 3.3 1.2 9.1 0.4 2.6 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta DUF4635 PF15466.1 KFM05072.1 - 1.9 7.7 8.9 10 5.4 1.7 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4635) CotJB PF12652.2 KFM05072.1 - 5.7 7.0 6.4 0.42 10.7 0.1 2.3 3 0 0 3 3 3 0 CotJB protein WW PF00397.21 KFM05073.1 - 3.4e-17 61.9 27.9 7.2e-10 38.5 3.4 3.5 4 0 0 4 4 4 2 WW domain zf-U1 PF06220.7 KFM05073.1 - 4.2e-15 55.0 0.7 7.7e-15 54.1 0.5 1.5 1 0 0 1 1 1 1 U1 zinc finger PQQ PF01011.16 KFM05073.1 - 0.032 13.7 0.3 0.77 9.4 0.0 2.5 2 0 0 2 2 2 0 PQQ enzyme repeat Elf-1_N PF12310.3 KFM05075.1 - 2.7e-36 123.7 0.4 2.7e-36 123.7 0.3 2.1 2 0 0 2 2 2 1 Transcription factor protein N terminal Ets PF00178.17 KFM05075.1 - 2.7e-35 120.3 2.4 4.2e-35 119.7 1.6 1.3 1 0 0 1 1 1 1 Ets-domain BRICHOS PF04089.9 KFM05076.1 - 1.1e-28 98.9 0.0 3.3e-28 97.3 0.0 1.8 2 0 0 2 2 2 1 BRICHOS domain Cadherin PF00028.12 KFM05077.1 - 1.8e-86 284.5 0.0 3.7e-19 68.7 0.0 6.2 6 0 0 6 6 6 5 Cadherin domain Cadherin_2 PF08266.7 KFM05077.1 - 1.1e-13 50.4 0.0 6.1e-11 41.7 0.0 4.0 3 0 0 3 3 3 1 Cadherin-like TMEM154 PF15102.1 KFM05077.1 - 0.0025 17.5 0.1 0.0049 16.5 0.1 1.4 1 0 0 1 1 1 1 TMEM154 protein family CD34_antigen PF06365.7 KFM05077.1 - 0.024 14.2 0.0 0.069 12.7 0.0 1.7 2 0 0 2 2 2 0 CD34/Podocalyxin family EphA2_TM PF14575.1 KFM05077.1 - 0.065 13.6 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain OLF PF02191.11 KFM05078.1 - 1.8e-84 282.9 8.0 2.8e-84 282.3 5.6 1.3 1 0 0 1 1 1 1 Olfactomedin-like domain Spc7 PF08317.6 KFM05078.1 - 1.3 7.6 9.9 3 6.4 6.9 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF3573 PF12097.3 KFM05078.1 - 2.9 6.4 7.0 1.9 7.0 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) Pox_A_type_inc PF04508.7 KFM05078.1 - 5 7.1 6.8 1.4 8.9 0.3 3.0 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Cadherin PF00028.12 KFM05081.1 - 1.2e-92 304.2 0.0 1e-17 64.1 0.0 6.5 6 0 0 6 6 6 6 Cadherin domain Cadherin_2 PF08266.7 KFM05081.1 - 3.7e-15 55.2 0.3 3.2e-09 36.2 0.0 4.5 5 0 0 5 5 5 2 Cadherin-like DUF1767 PF08585.7 KFM05082.1 - 1.9e-17 63.3 0.0 5.1e-17 61.9 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) SMN PF06003.7 KFM05082.1 - 2e-10 40.2 0.0 2e-10 40.2 0.0 2.7 2 1 0 2 2 2 1 Survival motor neuron protein (SMN) TUDOR PF00567.19 KFM05082.1 - 3.6e-10 39.7 0.0 7.9e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Tudor domain UBA PF00627.26 KFM05082.1 - 3.8e-10 39.2 0.3 8.2e-10 38.2 0.2 1.6 1 0 0 1 1 1 1 UBA/TS-N domain HBS1_N PF08938.5 KFM05082.1 - 0.013 15.5 0.5 0.062 13.4 0.0 2.2 2 0 0 2 2 2 0 HBS1 N-terminus UBA_4 PF14555.1 KFM05082.1 - 0.08 12.4 0.2 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 UBA-like domain Hex_IIIa PF02455.11 KFM05082.1 - 0.1 11.3 0.0 0.1 11.3 0.0 2.3 2 0 0 2 2 2 0 Hexon-associated protein (IIIa) Ribosomal_L18p PF00861.17 KFM05083.1 - 6.6e-45 152.1 0.1 1.2e-44 151.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 KFM05083.1 - 1.1e-35 122.0 8.0 2e-35 121.2 5.5 1.4 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region DUF1476 PF07345.6 KFM05083.1 - 0.0062 16.7 0.2 0.012 15.8 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1476) Cadherin PF00028.12 KFM05084.1 - 3.2e-90 296.5 0.0 9.6e-20 70.6 0.0 6.6 7 0 0 7 7 7 6 Cadherin domain Cadherin_2 PF08266.7 KFM05084.1 - 4.4e-13 48.6 0.0 9.1e-05 21.9 0.0 5.9 5 1 0 5 5 5 3 Cadherin-like Peptidase_A17 PF05380.8 KFM05085.1 - 0.15 11.8 1.3 0.64 9.8 0.0 2.2 1 1 1 2 2 2 0 Pao retrotransposon peptidase Cadherin PF00028.12 KFM05091.1 - 1.6e-102 335.9 11.3 6.7e-20 71.1 0.1 7.4 7 0 0 7 7 7 7 Cadherin domain Protocadherin PF08374.6 KFM05091.1 - 1e-96 322.8 0.6 2.6e-96 321.5 0.4 1.7 1 0 0 1 1 1 1 Protocadherin Cadherin_2 PF08266.7 KFM05091.1 - 6.4e-19 67.3 0.1 3e-08 33.0 0.0 6.1 6 0 0 6 6 6 3 Cadherin-like RCR PF12273.3 KFM05091.1 - 0.005 17.4 0.0 0.012 16.1 0.0 1.7 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red EphA2_TM PF14575.1 KFM05091.1 - 0.013 15.9 0.2 0.028 14.7 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.11 KFM05091.1 - 0.038 12.2 0.0 0.099 10.8 0.0 1.6 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E He_PIG PF05345.7 KFM05091.1 - 0.067 13.2 9.9 22 5.1 0.0 5.8 5 1 0 5 5 5 0 Putative Ig domain SHR3_chaperone PF08229.6 KFM05091.1 - 0.085 11.7 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 ER membrane protein SH3 CD34_antigen PF06365.7 KFM05091.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 CD34/Podocalyxin family BLVR PF06375.6 KFM05091.1 - 6.1 6.6 8.7 0.29 10.9 1.7 2.0 3 0 0 3 3 3 0 Bovine leukaemia virus receptor (BLVR) DUF2450 PF10475.4 KFM05092.1 - 1.4e-109 365.4 13.2 4.3e-109 363.9 9.2 1.9 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) DUF2451 PF10474.4 KFM05092.1 - 1.5e-100 335.8 2.5 1.5e-100 335.8 1.7 2.0 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) DUF4298 PF14131.1 KFM05092.1 - 0.2 11.5 5.3 2 8.3 0.1 4.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4298) I-set PF07679.11 KFM05093.1 - 2.7e-17 62.3 0.0 2.2e-09 37.0 0.0 4.0 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM05093.1 - 1.1e-14 54.2 0.1 3.5e-08 33.4 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.12 KFM05093.1 - 4.2e-14 52.4 0.1 7.1e-05 22.6 0.0 4.4 4 1 0 4 4 4 3 Immunoglobulin V-set domain Ig_3 PF13927.1 KFM05093.1 - 4.3e-14 52.7 8.3 1.2e-10 41.7 0.7 3.4 3 2 0 3 3 3 2 Immunoglobulin domain ig PF00047.20 KFM05093.1 - 3.8e-11 42.9 0.5 2.3e-06 27.6 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain C2-set_2 PF08205.7 KFM05093.1 - 0.0033 17.2 0.0 0.56 10.1 0.0 2.4 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain SLAM PF06214.6 KFM05093.1 - 0.13 12.1 0.0 1 9.3 0.0 2.2 2 1 0 2 2 2 0 Signaling lymphocytic activation molecule (SLAM) protein Pkinase PF00069.20 KFM05094.1 - 1.4e-69 234.1 0.0 1.6e-69 233.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM05094.1 - 3.1e-36 124.7 0.0 6.7e-36 123.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KFM05094.1 - 3.4e-07 30.2 0.1 0.0016 18.2 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KFM05094.1 - 8.9e-05 21.6 0.0 0.0002 20.5 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KFM05094.1 - 0.0006 18.8 0.0 0.0013 17.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 KFM05094.1 - 0.035 13.4 0.0 0.088 12.1 0.0 1.7 1 1 0 1 1 1 0 RIO1 family SR-25 PF10500.4 KFM05095.1 - 0.0064 15.9 41.3 0.0064 15.9 28.6 3.4 1 1 2 3 3 3 2 Nuclear RNA-splicing-associated protein RRM_5 PF13893.1 KFM05096.1 - 2.3e-07 30.5 0.1 4.5e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KFM05096.1 - 0.024 14.3 0.0 0.06 13.0 0.0 1.6 1 0 0 1 1 1 0 Limkain b1 AAA PF00004.24 KFM05097.1 - 1e-58 197.2 0.0 1.1e-42 145.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 KFM05097.1 - 4.7e-25 87.4 0.0 1e-24 86.3 0.0 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal PEX-2N PF09263.5 KFM05097.1 - 1.7e-20 73.1 0.0 4.2e-20 71.8 0.0 1.7 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_17 PF13207.1 KFM05097.1 - 3.9e-10 40.5 0.0 0.00011 22.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KFM05097.1 - 1.1e-09 38.5 0.7 0.001 19.0 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_14 PF13173.1 KFM05097.1 - 8.8e-08 32.1 0.0 0.0018 18.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KFM05097.1 - 2.4e-07 30.3 1.0 0.02 14.6 0.1 2.6 2 0 0 2 2 2 2 Part of AAA domain AAA_2 PF07724.9 KFM05097.1 - 4.6e-07 29.9 0.0 0.00099 19.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 KFM05097.1 - 5.1e-07 29.8 0.0 0.0038 17.3 0.0 3.0 2 0 0 2 2 2 2 RNA helicase Sigma54_activ_2 PF14532.1 KFM05097.1 - 2e-06 27.9 0.0 0.016 15.2 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain DUF815 PF05673.8 KFM05097.1 - 2.1e-06 26.8 0.0 0.00023 20.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NACHT PF05729.7 KFM05097.1 - 2.6e-06 27.1 5.0 0.013 15.1 0.9 4.7 4 1 0 4 4 4 1 NACHT domain AAA_33 PF13671.1 KFM05097.1 - 3.5e-06 26.9 0.0 0.082 12.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KFM05097.1 - 5.8e-06 26.0 0.2 0.17 11.6 0.1 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KFM05097.1 - 6.1e-06 25.4 0.0 0.00067 18.7 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 KFM05097.1 - 6.2e-06 25.7 0.1 0.11 11.9 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.1 KFM05097.1 - 1.7e-05 24.3 2.6 0.71 9.2 0.0 3.6 2 1 0 3 3 3 1 AAA domain AAA_22 PF13401.1 KFM05097.1 - 1.8e-05 24.8 1.8 0.27 11.3 0.1 3.5 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KFM05097.1 - 2.2e-05 24.7 0.0 0.057 13.7 0.0 3.0 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 KFM05097.1 - 2.3e-05 23.4 0.0 0.02 13.7 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein TIP49 PF06068.8 KFM05097.1 - 2.9e-05 22.9 0.3 0.021 13.5 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus Sigma54_activat PF00158.21 KFM05097.1 - 5.9e-05 22.5 0.0 0.12 11.7 0.0 2.9 3 0 0 3 3 2 2 Sigma-54 interaction domain AAA_28 PF13521.1 KFM05097.1 - 7.8e-05 22.6 0.0 0.4 10.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KFM05097.1 - 8.6e-05 21.9 1.7 0.0029 17.0 0.6 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 KFM05097.1 - 0.00013 21.0 0.1 0.23 10.5 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin ABC_tran PF00005.22 KFM05097.1 - 0.0015 18.8 5.4 0.063 13.5 0.3 3.6 3 1 0 3 3 3 1 ABC transporter Mg_chelatase PF01078.16 KFM05097.1 - 0.002 17.3 0.4 1.6 7.8 0.0 2.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 KFM05097.1 - 0.005 15.9 0.2 0.65 9.0 0.0 2.5 2 0 0 2 2 2 1 KaiC NB-ARC PF00931.17 KFM05097.1 - 0.0069 15.2 0.3 1.2 7.9 0.0 2.9 3 0 0 3 3 3 1 NB-ARC domain FtsK_SpoIIIE PF01580.13 KFM05097.1 - 0.023 14.1 0.1 0.23 10.9 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family APS_kinase PF01583.15 KFM05097.1 - 0.023 14.3 0.4 0.066 12.8 0.0 1.9 2 0 0 2 2 1 0 Adenylylsulphate kinase AAA_24 PF13479.1 KFM05097.1 - 0.032 13.8 0.1 1 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain CoaE PF01121.15 KFM05097.1 - 0.033 13.5 0.0 0.08 12.3 0.0 1.6 1 0 0 1 1 1 0 Dephospho-CoA kinase Dynamin_N PF00350.18 KFM05097.1 - 0.05 13.4 1.4 11 5.8 0.0 2.7 2 0 0 2 2 2 0 Dynamin family AAA_10 PF12846.2 KFM05097.1 - 0.056 12.8 0.4 0.25 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain Molydop_binding PF01568.16 KFM05097.1 - 0.057 13.2 0.0 0.16 11.7 0.0 1.8 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain DUF2138 PF09909.4 KFM05097.1 - 0.066 11.3 0.1 0.11 10.6 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2138) NTPase_1 PF03266.10 KFM05097.1 - 0.092 12.4 0.3 0.62 9.7 0.0 2.2 2 0 0 2 2 2 0 NTPase PhoH PF02562.11 KFM05097.1 - 0.1 11.8 0.0 1.9 7.6 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein MobB PF03205.9 KFM05097.1 - 0.11 12.1 0.3 0.29 10.8 0.1 1.8 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 KFM05097.1 - 0.13 11.8 0.3 8.9 5.9 0.1 2.8 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 Hpr_kinase_C PF07475.7 KFM05097.1 - 0.16 11.2 1.2 1.1 8.5 0.1 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain CPT PF07931.7 KFM05097.1 - 0.28 10.8 1.6 4.3 6.9 0.2 2.9 2 1 1 3 3 3 0 Chloramphenicol phosphotransferase-like protein Aminotran_1_2 PF00155.16 KFM05098.1 - 2.4e-60 204.4 0.0 3.2e-60 204.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KFM05098.1 - 1.1e-05 24.7 0.0 2.2e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Sipho_Gp37 PF14594.1 KFM05099.1 - 0.09 11.9 0.1 0.13 11.5 0.1 1.1 1 0 0 1 1 1 0 Siphovirus ReqiPepy6 Gp37-like protein IBR PF01485.16 KFM05100.1 - 3e-21 75.0 40.5 1.4e-13 50.4 0.9 5.1 4 1 1 5 5 5 2 IBR domain Ank_2 PF12796.2 KFM05100.1 - 9.6e-16 57.9 0.4 3e-10 40.2 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFM05100.1 - 1.3e-12 47.4 0.9 5.2e-08 32.8 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KFM05100.1 - 5.9e-12 44.7 0.0 1.7e-06 27.5 0.0 3.0 2 1 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 KFM05100.1 - 1.2e-07 32.0 0.6 0.0068 16.9 0.0 3.6 4 1 1 5 5 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM05100.1 - 8.4e-07 28.6 1.7 0.005 16.9 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat zf-RING_2 PF13639.1 KFM05100.1 - 5.7e-05 22.8 5.5 5.7e-05 22.8 3.8 3.9 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4_4 PF15227.1 KFM05100.1 - 0.0027 17.5 6.5 0.0027 17.5 4.5 4.2 3 1 1 4 4 4 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KFM05100.1 - 0.0046 16.5 6.1 0.0046 16.5 4.2 4.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM05100.1 - 0.0081 16.1 8.9 0.0081 16.1 6.2 4.4 3 1 0 3 3 2 2 Zinc finger, C3HC4 type (RING finger) UIM PF02809.15 KFM05100.1 - 0.018 14.5 1.8 0.036 13.6 0.3 2.3 2 0 0 2 2 2 0 Ubiquitin interaction motif FERM_M PF00373.13 KFM05101.1 - 4.4e-20 72.1 0.1 1.2e-19 70.7 0.0 1.8 1 0 0 1 1 1 1 FERM central domain Ank_5 PF13857.1 KFM05101.1 - 8.2e-18 64.0 0.3 1.5e-10 40.9 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 KFM05101.1 - 4.6e-16 58.9 0.0 1.5e-08 34.8 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFM05101.1 - 2.2e-12 47.1 0.5 5.3e-07 29.9 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 KFM05101.1 - 3e-12 45.6 0.2 0.0026 17.4 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 KFM05101.1 - 6.9e-10 38.1 0.1 0.011 15.9 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat p450 PF00067.17 KFM05102.1 - 7.9e-79 265.3 0.0 9.3e-79 265.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Frizzled PF01534.12 KFM05104.1 - 2.8e-155 516.0 13.4 3.4e-155 515.7 9.3 1.0 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.17 KFM05104.1 - 1.5e-35 122.0 4.8 3.3e-35 120.9 3.3 1.6 1 0 0 1 1 1 1 Fz domain Dicty_CAR PF05462.6 KFM05104.1 - 0.00011 21.1 3.0 0.00024 20.0 2.1 1.5 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Pkinase PF00069.20 KFM05105.1 - 4.5e-66 222.6 0.0 5.6e-66 222.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM05105.1 - 1.3e-32 112.8 0.0 1.8e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM05105.1 - 0.00063 18.7 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFM05105.1 - 0.0017 18.1 0.0 0.071 12.8 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family IncA PF04156.9 KFM05106.1 - 1.8e-05 24.4 2.0 3.1e-05 23.6 1.2 1.5 1 1 0 1 1 1 1 IncA protein CD34_antigen PF06365.7 KFM05106.1 - 0.00034 20.3 2.1 0.00034 20.3 1.5 1.5 1 1 0 1 1 1 1 CD34/Podocalyxin family Shisa PF13908.1 KFM05106.1 - 0.00036 20.7 0.1 0.00036 20.7 0.0 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator UPF0560 PF10577.4 KFM05106.1 - 0.00064 18.1 0.3 0.00064 18.1 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0560 DUF2681 PF10883.3 KFM05106.1 - 0.00078 19.6 0.2 0.0013 18.8 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2681) EphA2_TM PF14575.1 KFM05106.1 - 0.0015 18.8 0.3 0.0024 18.2 0.2 1.4 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.11 KFM05106.1 - 0.003 15.8 0.1 0.003 15.8 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E FAM163 PF15069.1 KFM05106.1 - 0.0036 17.8 0.5 0.005 17.4 0.3 1.3 1 0 0 1 1 1 1 FAM163 family Protocadherin PF08374.6 KFM05106.1 - 0.0042 16.7 0.0 0.0043 16.7 0.0 1.1 1 0 0 1 1 1 1 Protocadherin DUF1191 PF06697.7 KFM05106.1 - 0.0061 15.4 0.0 0.0069 15.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Corona_S2 PF01601.11 KFM05106.1 - 0.01 13.9 1.2 0.012 13.7 0.8 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein FAM176 PF14851.1 KFM05106.1 - 0.012 15.3 0.2 0.013 15.1 0.2 1.1 1 0 0 1 1 1 0 FAM176 family DUF3609 PF12259.3 KFM05106.1 - 0.017 13.8 0.1 0.02 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) 7tm_1 PF00001.16 KFM05106.1 - 0.019 14.0 0.1 0.024 13.8 0.1 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) TMEM154 PF15102.1 KFM05106.1 - 0.033 13.8 0.1 0.047 13.3 0.0 1.4 1 1 0 1 1 1 0 TMEM154 protein family LST1 PF05083.8 KFM05106.1 - 0.04 13.8 2.5 0.079 12.9 1.8 1.4 1 0 0 1 1 1 0 LST-1 protein Rhabdo_glycop PF00974.13 KFM05106.1 - 0.059 11.6 0.5 0.071 11.3 0.4 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein DUF4500 PF14937.1 KFM05106.1 - 0.071 12.9 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) BatD PF13584.1 KFM05106.1 - 0.086 11.4 0.0 0.11 11.1 0.0 1.0 1 0 0 1 1 1 0 Oxygen tolerance DUF3481 PF11980.3 KFM05106.1 - 0.091 12.5 0.2 0.13 12.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) GP41 PF00517.12 KFM05106.1 - 0.1 12.1 0.1 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Retroviral envelope protein CCER1 PF15482.1 KFM05106.1 - 0.11 12.1 1.7 0.13 11.8 1.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 MAS20 PF02064.10 KFM05106.1 - 0.16 11.8 1.5 0.21 11.5 1.1 1.2 1 0 0 1 1 1 0 MAS20 protein import receptor SCIMP PF15050.1 KFM05106.1 - 0.19 11.6 0.8 0.29 11.0 0.5 1.4 1 0 0 1 1 1 0 SCIMP protein Orthoreo_P10 PF07204.6 KFM05106.1 - 0.37 10.5 4.3 0.5 10.1 2.8 1.4 1 1 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Synaptobrevin PF00957.16 KFM05106.1 - 0.99 9.0 4.3 1.9 8.1 3.0 1.4 1 0 0 1 1 1 0 Synaptobrevin Prominin PF05478.6 KFM05106.1 - 2.5 5.5 6.4 3 5.2 4.4 1.0 1 0 0 1 1 1 0 Prominin Claudin_2 PF13903.1 KFM05107.1 - 3.8e-07 29.9 9.2 4.6e-07 29.6 6.0 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 KFM05107.1 - 0.00091 18.9 5.0 0.0014 18.3 3.5 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family MMR_HSR1 PF01926.18 KFM05108.1 - 1.8e-21 76.2 0.0 2.9e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP1_OBG PF01018.17 KFM05108.1 - 1.1e-16 60.8 4.2 1.2e-15 57.4 2.9 2.3 1 1 0 1 1 1 1 GTP1/OBG FeoB_N PF02421.13 KFM05108.1 - 1e-11 44.3 0.1 1.6e-10 40.4 0.1 2.5 2 1 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KFM05108.1 - 2.9e-05 23.5 0.1 0.0034 16.8 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 KFM05108.1 - 6e-05 21.9 0.1 0.083 11.6 0.0 2.2 2 0 0 2 2 2 2 ArgK protein Arf PF00025.16 KFM05108.1 - 0.00095 18.4 0.0 0.0019 17.4 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family ATP_bind_1 PF03029.12 KFM05108.1 - 0.011 15.2 0.1 0.074 12.5 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein UvrD-helicase PF00580.16 KFM05108.1 - 0.031 13.5 0.8 0.049 12.9 0.1 1.6 1 1 1 2 2 2 0 UvrD/REP helicase N-terminal domain Dynamin_N PF00350.18 KFM05108.1 - 0.47 10.2 2.3 5.5 6.7 0.2 2.7 2 1 0 2 2 2 0 Dynamin family Ferric_reduct PF01794.14 KFM05111.1 - 2.8e-19 69.4 4.6 2.8e-19 69.4 3.2 2.6 2 1 1 3 3 3 2 Ferric reductase like transmembrane component F420_oxidored PF03807.12 KFM05111.1 - 1.3e-17 63.9 0.0 2.4e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 KFM05111.1 - 4.9e-06 26.4 0.0 8.1e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 KFM05111.1 - 0.0008 18.6 0.0 0.0014 17.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DctQ PF04290.7 KFM05111.1 - 0.0084 15.8 6.4 0.74 9.5 0.1 3.0 3 0 0 3 3 3 2 Tripartite ATP-independent periplasmic transporters, DctQ component NAD_binding_10 PF13460.1 KFM05111.1 - 0.01 15.8 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding IlvN PF07991.7 KFM05111.1 - 0.025 13.9 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain DUF202 PF02656.10 KFM05111.1 - 0.051 13.7 6.0 0.37 11.0 0.3 3.0 3 0 0 3 3 2 0 Domain of unknown function (DUF202) NAD_binding_7 PF13241.1 KFM05111.1 - 0.086 13.1 0.1 0.31 11.3 0.1 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding Neurensin PF14927.1 KFM05111.1 - 0.12 11.7 0.5 4.1 6.7 0.1 2.4 2 0 0 2 2 2 0 Neurensin DUF2768 PF10966.3 KFM05111.1 - 0.92 9.6 7.3 0.19 11.9 1.8 2.4 2 0 0 2 2 1 0 Protein of unknown function (DUF2768) Ferric_reduct PF01794.14 KFM05112.1 - 3.9e-17 62.4 15.8 6e-17 61.9 4.7 2.6 2 1 1 3 3 3 2 Ferric reductase like transmembrane component DUF3671 PF12420.3 KFM05112.1 - 0.16 11.9 6.7 0.26 11.3 0.3 2.8 2 1 0 2 2 2 0 Protein of unknown function zf-C2H2_jaz PF12171.3 KFM05113.1 - 1.1e-05 25.4 10.0 1.1e-05 25.4 6.9 2.9 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding Ferric_reduct PF01794.14 KFM05115.1 - 2.4e-24 85.8 5.2 2.4e-24 85.8 3.6 2.3 1 1 1 2 2 2 2 Ferric reductase like transmembrane component F420_oxidored PF03807.12 KFM05115.1 - 2.1e-12 47.3 0.0 3.9e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 KFM05115.1 - 0.0017 18.2 0.0 0.0027 17.5 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 KFM05115.1 - 0.0026 17.1 0.0 0.0038 16.5 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 KFM05115.1 - 0.0079 15.3 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Rossmann-like PF10727.4 KFM05115.1 - 0.13 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Rossmann-like domain NAD_binding_10 PF13460.1 KFM05115.1 - 0.15 12.0 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 NADH(P)-binding EF-hand_1 PF00036.27 KFM05116.1 - 2e-18 64.1 0.3 0.00011 21.2 0.0 5.3 5 1 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 KFM05116.1 - 3.8e-17 61.6 0.0 3.2e-13 49.0 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.1 KFM05116.1 - 1.9e-14 53.5 0.3 1.6e-06 28.1 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 KFM05116.1 - 5.3e-14 50.7 0.6 0.00034 20.2 0.0 4.8 4 1 1 5 5 5 3 EF-hand domain EF-hand_5 PF13202.1 KFM05116.1 - 1.6e-12 46.1 0.3 0.00076 18.7 0.0 4.0 4 0 0 4 4 4 3 EF hand Reprolysin PF01421.14 KFM05117.1 - 2.6e-55 187.0 0.0 5.7e-55 186.0 0.0 1.6 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.7 KFM05117.1 - 5.8e-30 103.7 7.0 5.8e-30 103.7 4.9 3.7 3 2 0 3 3 3 1 ADAM cysteine-rich Disintegrin PF00200.18 KFM05117.1 - 2.9e-18 65.8 29.6 2.9e-18 65.8 20.5 3.6 3 1 0 3 3 3 1 Disintegrin Pep_M12B_propep PF01562.14 KFM05117.1 - 3.7e-15 55.8 0.4 7.2e-15 54.9 0.3 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_3 PF13582.1 KFM05117.1 - 3.8e-09 37.1 0.0 7.9e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KFM05117.1 - 1.3e-06 28.4 0.0 3.6e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KFM05117.1 - 0.0001 21.8 0.1 0.00036 20.1 0.1 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFM05117.1 - 0.0003 20.9 0.1 0.0046 17.0 0.1 2.4 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like EGF_2 PF07974.8 KFM05117.1 - 0.0036 17.4 11.4 0.0036 17.4 7.9 6.6 4 2 1 5 5 5 1 EGF-like domain Mito_carr PF00153.22 KFM05118.1 - 4.7e-64 212.1 0.3 4.8e-22 77.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein RUN PF02759.14 KFM05119.1 - 5.6e-29 100.5 0.1 1.4e-28 99.2 0.0 1.7 2 0 0 2 2 2 1 RUN domain ERM PF00769.14 KFM05119.1 - 0.018 14.5 2.4 0.028 13.9 1.7 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Drf_FH3 PF06367.11 KFM05119.1 - 0.03 13.7 4.7 0.064 12.6 3.3 1.5 1 0 0 1 1 1 0 Diaphanous FH3 Domain DUF4477 PF14780.1 KFM05119.1 - 0.035 13.4 0.5 0.27 10.5 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4477) Carn_acyltransf PF00755.15 KFM05121.1 - 5.7e-191 635.6 0.0 6.5e-191 635.4 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Thioesterase PF00975.15 KFM05122.1 - 1.8e-43 149.4 0.0 2.1e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 KFM05122.1 - 3.3e-07 30.4 0.0 5e-07 29.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFM05122.1 - 7.1e-06 25.8 0.0 9.9e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 KFM05122.1 - 0.002 17.7 0.0 0.003 17.1 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.15 KFM05122.1 - 0.062 12.8 0.0 0.12 11.9 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF2305 PF10230.4 KFM05122.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) ACBP PF00887.14 KFM05123.1 - 2.3e-30 104.0 0.5 2.5e-30 103.9 0.3 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein JmjN PF02375.12 KFM05123.1 - 0.57 9.7 2.3 5.5 6.5 0.3 2.1 2 0 0 2 2 2 0 jmjN domain Ribosomal_L7Ae PF01248.21 KFM05124.1 - 1.2e-07 31.1 0.0 3e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 KFM05124.1 - 3.9e-06 26.7 0.0 0.0012 18.6 0.0 2.2 2 0 0 2 2 2 2 RNase P subunit Pop3 NMT_C PF02799.10 KFM05125.1 - 2.7e-83 278.0 0.3 8.5e-83 276.4 0.1 1.8 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 KFM05125.1 - 2.2e-81 271.2 0.0 3.5e-81 270.5 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_7 PF13508.1 KFM05125.1 - 0.0097 16.0 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFM05125.1 - 0.014 15.2 0.0 0.071 12.9 0.0 2.2 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFM05125.1 - 0.039 13.9 0.0 0.081 12.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family NST1 PF13945.1 KFM05125.1 - 0.14 12.2 5.4 0.23 11.4 3.8 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator UPF0560 PF10577.4 KFM05126.1 - 0 1278.1 5.5 0 1277.9 3.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0560 MG1 PF11974.3 KFM05126.1 - 0.013 15.9 0.1 0.095 13.2 0.0 2.4 2 0 0 2 2 2 0 Alpha-2-macroglobulin MG1 domain DUF4131 PF13567.1 KFM05126.1 - 0.057 12.8 0.2 3.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Alpha_E2_glycop PF00943.14 KFM05126.1 - 0.083 11.5 0.3 0.15 10.7 0.2 1.3 1 0 0 1 1 1 0 Alphavirus E2 glycoprotein Orthoreo_P10 PF07204.6 KFM05126.1 - 0.092 12.4 0.1 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 IncA PF04156.9 KFM05126.1 - 0.12 12.0 0.1 0.12 12.0 0.0 2.3 2 0 0 2 2 2 0 IncA protein Adeno_E3_CR2 PF02439.10 KFM05126.1 - 0.2 11.1 1.5 0.37 10.3 1.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Integrin_alpha2 PF08441.7 KFM05127.1 - 1e-98 331.1 0.0 1.3e-98 330.8 0.0 1.1 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.18 KFM05127.1 - 5.1e-20 70.5 17.2 2.9e-08 33.1 0.0 5.2 5 0 0 5 5 5 4 FG-GAP repeat VCBS PF13517.1 KFM05127.1 - 1.7e-09 37.9 8.4 3.9e-07 30.3 1.1 4.2 1 1 4 5 5 5 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.1 KFM05127.1 - 0.012 15.5 3.6 0.57 10.2 0.0 4.7 5 0 0 5 5 5 0 FG-GAP repeat DUF4205 PF13898.1 KFM05128.1 - 3.7e-57 193.6 0.1 6.4e-51 173.1 0.0 3.0 2 1 0 2 2 2 2 Domain of unknown function (DUF4205) PTE PF02126.13 KFM05129.1 - 8.5e-119 396.1 0.0 9.7e-119 395.9 0.0 1.0 1 0 0 1 1 1 1 Phosphotriesterase family TatD_DNase PF01026.16 KFM05129.1 - 2e-07 30.5 0.0 3.3e-07 29.7 0.0 1.4 1 1 0 1 1 1 1 TatD related DNase KH_1 PF00013.24 KFM05129.1 - 0.013 15.0 0.0 0.037 13.6 0.0 1.9 1 0 0 1 1 1 0 KH domain Amidohydro_2 PF04909.9 KFM05129.1 - 0.066 12.7 0.0 0.14 11.7 0.0 1.5 1 1 0 1 1 1 0 Amidohydrolase C1q PF00386.16 KFM05130.1 - 4.8e-12 45.9 0.0 5e-12 45.9 0.0 1.0 1 0 0 1 1 1 1 C1q domain TNF PF00229.13 KFM05130.1 - 0.044 13.3 0.0 0.048 13.2 0.0 1.0 1 0 0 1 1 1 0 TNF(Tumour Necrosis Factor) family LRR_4 PF12799.2 KFM05131.1 - 5.8e-25 86.4 22.2 1.2e-08 34.3 2.1 4.7 1 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM05131.1 - 5.4e-18 64.5 14.2 2.1e-09 36.9 2.7 3.2 1 1 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 KFM05131.1 - 8.9e-18 61.6 20.1 0.0074 16.1 0.1 6.4 6 0 0 6 6 6 6 Leucine Rich Repeat LRR_7 PF13504.1 KFM05131.1 - 1.4e-10 39.5 17.1 1 9.8 0.0 6.9 7 0 0 7 7 7 6 Leucine rich repeat LRR_6 PF13516.1 KFM05131.1 - 4.4e-06 26.2 19.4 2.7 8.3 0.3 6.4 6 0 0 6 6 6 4 Leucine Rich repeat CUB PF00431.15 KFM05132.1 - 0 2368.0 31.3 1.1e-32 112.3 0.0 27.1 27 0 0 27 27 27 27 CUB domain EGF_CA PF07645.10 KFM05132.1 - 5.5e-20 71.0 103.3 3.3e-07 30.1 5.4 8.9 6 2 2 8 8 8 6 Calcium-binding EGF domain EGF PF00008.22 KFM05132.1 - 4.2e-18 64.9 105.4 2.1e-07 30.7 3.1 9.2 8 0 0 8 8 8 5 EGF-like domain CUB_2 PF02408.15 KFM05132.1 - 2.9e-16 59.0 62.7 0.017 14.6 0.0 20.2 25 0 0 25 25 25 6 CUB-like domain FXa_inhibition PF14670.1 KFM05132.1 - 6.6e-10 38.9 106.2 2.8e-05 24.1 6.8 9.2 7 1 1 8 8 8 4 Coagulation Factor Xa inhibitory site EGF_3 PF12947.2 KFM05132.1 - 1.4e-08 34.5 91.2 2.9e-06 27.1 2.1 9.0 8 0 0 8 8 8 4 EGF domain Ribosomal_S15 PF00312.17 KFM05132.1 - 0.1 12.3 0.2 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein S15 Phage_GP20 PF06810.6 KFM05132.1 - 0.57 9.6 1.1 0.92 8.9 0.8 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 Seryl_tRNA_N PF02403.17 KFM05132.1 - 1.4 8.9 3.5 2.4 8.2 2.5 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain BicD PF09730.4 KFM05132.1 - 1.9 6.7 0.1 2.8 6.1 0.1 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D Syntaxin PF00804.20 KFM05132.1 - 2.7 8.1 1.1 4.8 7.3 0.7 1.3 1 0 0 1 1 1 0 Syntaxin TBPIP PF07106.8 KFM05132.1 - 3.5 7.1 1.7 5.7 6.4 1.2 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Tropomyosin_1 PF12718.2 KFM05132.1 - 4.6 7.0 1.0 7.2 6.4 0.7 1.2 1 0 0 1 1 1 0 Tropomyosin like DUF2076 PF09849.4 KFM05132.1 - 5.3 7.0 0.0 9.1 6.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) ATG16 PF08614.6 KFM05132.1 - 7 6.4 1.6 12 5.7 1.1 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) IFT57 PF10498.4 KFM05132.1 - 7.7 5.1 1.0 22 3.6 0.3 1.8 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DNA_methylase PF00145.12 KFM05133.1 - 6.1e-36 124.2 0.0 9.2e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Glyco_transf_29 PF00777.13 KFM05134.1 - 4.1e-76 255.6 0.0 6.3e-76 255.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) DUF2636 PF11120.3 KFM05134.1 - 0.036 13.5 0.2 0.077 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2636) PTPLA PF04387.9 KFM05135.1 - 8.6e-59 197.6 13.8 1e-58 197.4 9.6 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA VHS PF00790.14 KFM05136.1 - 3.6e-44 149.8 1.4 4.7e-44 149.4 0.1 1.9 2 0 0 2 2 2 1 VHS domain SH3_1 PF00018.23 KFM05136.1 - 3e-16 58.5 0.1 5.7e-16 57.6 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFM05136.1 - 2.6e-13 49.3 0.0 4.5e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFM05136.1 - 2.6e-12 46.0 0.0 4.6e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.15 KFM05136.1 - 0.00021 20.6 0.6 0.00063 19.1 0.4 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif HEAT_2 PF13646.1 KFM05136.1 - 0.052 13.8 0.1 0.59 10.4 0.0 2.7 3 0 0 3 3 3 0 HEAT repeats HEAT PF02985.17 KFM05136.1 - 0.21 11.7 1.1 0.76 10.0 0.0 2.4 2 0 0 2 2 2 0 HEAT repeat Lectin_C PF00059.16 KFM05137.1 - 2e-70 234.1 13.8 2e-23 83.0 0.2 5.2 5 0 0 5 5 5 4 Lectin C-type domain fn2 PF00040.14 KFM05137.1 - 1.4e-14 53.8 8.5 1.4e-14 53.8 5.9 2.7 2 1 1 3 3 3 1 Fibronectin type II domain Herpes_UL45 PF05473.7 KFM05137.1 - 5.5e-09 35.7 0.2 3.3e-06 26.6 0.0 3.3 3 0 0 3 3 3 1 UL45 protein Ricin_B_lectin PF00652.17 KFM05137.1 - 8.1e-08 32.3 0.5 2.2e-07 30.9 0.3 1.8 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Chordopox_A33R PF05966.7 KFM05137.1 - 6.3e-07 28.3 1.6 0.00052 18.8 0.0 3.2 3 0 0 3 3 3 2 Chordopoxvirus A33R protein Xlink PF00193.12 KFM05137.1 - 0.00029 20.8 1.7 7 6.8 0.2 4.7 4 1 0 4 4 4 2 Extracellular link domain Lectin_C PF00059.16 KFM05138.1 - 6e-157 512.1 57.4 1.2e-21 77.3 1.0 8.9 9 0 0 9 9 9 8 Lectin C-type domain Herpes_UL45 PF05473.7 KFM05138.1 - 6.4e-18 64.8 14.3 3.4e-06 26.6 0.0 6.5 5 1 2 7 7 7 4 UL45 protein fn2 PF00040.14 KFM05138.1 - 6.5e-13 48.4 3.6 6.5e-13 48.4 2.5 3.1 3 0 0 3 3 3 1 Fibronectin type II domain Xlink PF00193.12 KFM05138.1 - 4.8e-12 45.8 4.4 0.41 10.7 0.0 7.5 7 1 1 8 8 8 4 Extracellular link domain Ricin_B_lectin PF00652.17 KFM05138.1 - 1.6e-07 31.4 0.8 5.3e-07 29.6 0.6 2.0 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Chordopox_A33R PF05966.7 KFM05138.1 - 1.5e-06 27.1 17.8 0.042 12.6 0.0 7.0 8 0 0 8 8 8 3 Chordopoxvirus A33R protein Intimin_C PF07979.6 KFM05138.1 - 0.00038 20.6 4.5 60 3.9 0.0 6.8 8 0 0 8 8 8 0 Intimin C-type lectin domain Lectin_C PF00059.16 KFM05140.1 - 1.5e-73 244.0 14.3 2.4e-23 82.7 0.8 4.9 5 0 0 5 5 5 4 Lectin C-type domain fn2 PF00040.14 KFM05140.1 - 2.5e-18 65.8 8.3 2.5e-18 65.8 5.8 2.5 2 0 0 2 2 2 1 Fibronectin type II domain Ricin_B_lectin PF00652.17 KFM05140.1 - 3.1e-10 40.1 0.6 3.1e-10 40.1 0.4 2.7 4 0 0 4 4 4 1 Ricin-type beta-trefoil lectin domain Herpes_UL45 PF05473.7 KFM05140.1 - 9.8e-08 31.6 8.6 0.003 16.9 0.3 4.5 3 1 1 4 4 4 3 UL45 protein Chordopox_A33R PF05966.7 KFM05140.1 - 1.7e-05 23.6 8.7 0.098 11.4 0.2 3.6 4 0 0 4 4 4 3 Chordopoxvirus A33R protein Xlink PF00193.12 KFM05140.1 - 0.0002 21.3 5.8 6.9 6.8 0.1 5.4 5 0 0 5 5 5 2 Extracellular link domain RicinB_lectin_2 PF14200.1 KFM05140.1 - 0.0017 18.6 2.5 0.0045 17.3 0.0 2.9 3 0 0 3 3 3 1 Ricin-type beta-trefoil lectin domain-like Lectin_C PF00059.16 KFM05141.1 - 2.1e-69 230.7 10.5 1.4e-19 70.6 0.3 4.3 4 0 0 4 4 4 4 Lectin C-type domain fn2 PF00040.14 KFM05141.1 - 2.7e-18 65.6 5.0 7.3e-18 64.2 3.4 1.8 1 0 0 1 1 1 1 Fibronectin type II domain Herpes_UL45 PF05473.7 KFM05141.1 - 1.6e-10 40.7 1.5 5.2e-05 22.7 0.0 3.6 3 1 1 4 4 4 2 UL45 protein Chordopox_A33R PF05966.7 KFM05141.1 - 1.3e-07 30.5 2.8 0.0029 16.4 0.1 3.6 4 0 0 4 4 4 2 Chordopoxvirus A33R protein Xlink PF00193.12 KFM05141.1 - 7.4e-07 29.1 3.6 0.71 9.9 0.0 5.3 5 0 0 5 5 5 2 Extracellular link domain MBT PF02820.13 KFM05141.1 - 0.02 14.8 0.0 0.53 10.2 0.0 2.5 2 0 0 2 2 2 0 mbt repeat Intimin_C PF07979.6 KFM05141.1 - 0.032 14.4 0.9 78 3.5 0.0 4.3 5 0 0 5 5 5 0 Intimin C-type lectin domain Lectin_C PF00059.16 KFM05142.1 - 2.2e-16 60.4 0.7 3e-16 59.9 0.1 1.5 2 0 0 2 2 2 1 Lectin C-type domain DUF4366 PF14283.1 KFM05142.1 - 0.0032 16.9 0.0 0.0042 16.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) MFS_Mycoplasma PF07672.8 KFM05142.1 - 0.0039 16.4 0.1 0.0066 15.6 0.1 1.3 1 0 0 1 1 1 1 Mycoplasma MFS transporter RIC3 PF15361.1 KFM05142.1 - 0.16 12.2 0.2 1.5 9.0 0.0 2.0 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Lectin_C PF00059.16 KFM05143.1 - 1.4e-150 491.6 64.0 3.2e-21 75.9 0.0 9.3 9 0 0 9 9 9 8 Lectin C-type domain Herpes_UL45 PF05473.7 KFM05143.1 - 1.7e-17 63.5 9.5 0.0027 17.1 0.0 8.1 7 1 2 9 9 9 4 UL45 protein fn2 PF00040.14 KFM05143.1 - 1.9e-16 59.7 1.0 1.2e-15 57.1 0.7 2.6 1 0 0 1 1 1 1 Fibronectin type II domain Ricin_B_lectin PF00652.17 KFM05143.1 - 5.7e-09 36.0 1.6 5.7e-09 36.0 1.1 2.6 3 0 0 3 3 3 1 Ricin-type beta-trefoil lectin domain Xlink PF00193.12 KFM05143.1 - 6.4e-07 29.3 8.3 2.9 8.0 0.1 7.6 8 0 0 8 8 8 3 Extracellular link domain Chordopox_A33R PF05966.7 KFM05143.1 - 3.4e-06 25.9 15.3 2.2 7.0 0.0 7.0 7 0 0 7 7 7 4 Chordopoxvirus A33R protein Intimin_C PF07979.6 KFM05143.1 - 0.00033 20.8 9.2 28 4.9 0.0 7.2 7 0 0 7 7 7 0 Intimin C-type lectin domain Zip PF02535.17 KFM05144.1 - 3.5e-58 197.0 8.7 5.7e-58 196.4 6.1 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter Tox-SGS PF15651.1 KFM05144.1 - 0.02 14.6 0.1 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 Salivary glad secreted protein domain toxin zf-C2H2 PF00096.21 KFM05145.1 - 8.1e-43 142.2 44.3 4.7e-08 32.9 0.2 7.1 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM05145.1 - 6.4e-39 130.3 35.9 5.5e-09 35.8 0.1 7.3 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM05145.1 - 5e-24 82.8 40.6 5.1e-05 23.3 0.4 7.1 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM05145.1 - 4.2e-21 74.1 39.7 2e-06 27.4 0.9 7.2 7 0 0 7 7 7 5 C2H2-type zinc finger C1_1 PF00130.17 KFM05145.1 - 1.7e-07 30.8 10.9 0.078 12.7 0.2 4.4 1 1 4 5 5 5 4 Phorbol esters/diacylglycerol binding domain (C1 domain) XPA_N PF01286.13 KFM05145.1 - 1.6e-06 27.6 14.0 2.6 7.7 0.0 6.1 6 1 0 6 6 6 2 XPA protein N-terminal DZR PF12773.2 KFM05145.1 - 0.00032 20.4 24.8 0.43 10.4 1.5 4.0 1 1 3 4 4 4 3 Double zinc ribbon FYDLN_acid PF09538.5 KFM05145.1 - 0.00033 21.1 10.2 5.7 7.5 0.0 5.5 1 1 4 5 5 5 0 Protein of unknown function (FYDLN_acid) Zn-ribbon_8 PF09723.5 KFM05145.1 - 0.00053 19.8 27.3 0.32 10.9 2.6 5.9 3 1 2 5 5 5 2 Zinc ribbon domain zf-C2H2_jaz PF12171.3 KFM05145.1 - 0.00067 19.7 24.9 0.48 10.6 0.0 6.2 7 0 0 7 7 6 3 Zinc-finger double-stranded RNA-binding DNA_RNApol_7kD PF03604.8 KFM05145.1 - 0.00075 18.9 23.2 1.4 8.4 0.0 6.2 6 0 0 6 6 6 2 DNA directed RNA polymerase, 7 kDa subunit zf-LYAR PF08790.6 KFM05145.1 - 0.0011 18.6 13.0 2.4 7.9 0.0 5.0 5 0 0 5 5 5 1 LYAR-type C2HC zinc finger zf-Di19 PF05605.7 KFM05145.1 - 0.002 18.1 16.7 0.23 11.6 0.5 3.9 2 1 2 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding RRN7 PF11781.3 KFM05145.1 - 0.0095 15.4 19.1 2.5 7.6 0.1 6.0 6 0 0 6 6 6 1 RNA polymerase I-specific transcription initiation factor Rrn7 GAGA PF09237.6 KFM05145.1 - 0.013 15.1 16.2 0.22 11.1 0.0 4.6 1 1 4 5 5 5 0 GAGA factor zf-CHY PF05495.7 KFM05145.1 - 0.017 15.2 20.0 2.1 8.5 1.0 3.4 1 1 2 3 3 3 0 CHY zinc finger zf-H2C2_5 PF13909.1 KFM05145.1 - 0.023 14.9 33.1 0.79 10.0 0.0 7.6 7 1 0 7 7 7 0 C2H2-type zinc-finger domain zinc_ribbon_2 PF13240.1 KFM05145.1 - 0.024 14.1 0.3 0.024 14.1 0.2 5.4 4 2 0 4 4 4 0 zinc-ribbon domain C1_4 PF07975.7 KFM05145.1 - 0.053 13.5 15.7 0.54 10.2 0.8 4.5 1 1 4 5 5 5 0 TFIIH C1-like domain zf-ISL3 PF14690.1 KFM05145.1 - 0.19 11.8 28.4 4.9 7.2 0.7 6.2 6 0 0 6 6 6 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DUF2321 PF10083.4 KFM05145.1 - 0.2 11.1 15.5 1.1 8.7 0.1 4.8 1 1 4 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2321) Zn_ribbon_recom PF13408.1 KFM05145.1 - 0.4 10.9 27.2 35 4.7 0.5 5.2 2 2 1 3 3 3 0 Recombinase zinc beta ribbon domain CpXC PF14353.1 KFM05145.1 - 0.51 10.3 15.3 8.5 6.3 0.2 5.5 2 1 3 5 5 5 0 CpXC protein Mut7-C PF01927.11 KFM05145.1 - 0.56 10.1 11.3 1.7 8.5 0.4 3.0 1 1 2 3 3 3 0 Mut7-C RNAse domain zf-trcl PF13451.1 KFM05145.1 - 1.1 8.9 23.0 1.2 8.7 0.0 5.6 4 1 1 5 5 4 0 Probable zinc-binding domain FdhD-NarQ PF02634.10 KFM05145.1 - 5.3 6.4 11.1 15 4.9 0.8 3.4 1 1 3 4 4 4 0 FdhD/NarQ family LIM PF00412.17 KFM05145.1 - 5.9 7.0 20.0 6.4 6.9 0.6 4.1 2 1 2 4 4 4 0 LIM domain Stig1 PF04885.8 KFM05145.1 - 6.7 6.9 19.6 0.45 10.7 3.6 2.7 1 1 0 2 2 2 0 Stigma-specific protein, Stig1 YhfH PF14149.1 KFM05145.1 - 9.9 6.0 24.1 21 4.9 0.1 5.9 6 0 0 6 6 6 0 YhfH-like protein Ank_2 PF12796.2 KFM05146.1 - 1.2e-37 128.1 3.6 2.5e-22 79.0 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFM05146.1 - 8.9e-36 119.9 6.9 2.4e-10 39.6 0.0 5.8 5 1 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 KFM05146.1 - 1.3e-32 111.5 7.0 8.1e-12 45.3 0.2 5.2 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM05146.1 - 6.4e-29 99.3 10.8 1.1e-13 50.9 0.8 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM05146.1 - 1.9e-23 80.2 5.4 2.5e-05 24.0 0.0 5.0 5 0 0 5 5 5 4 Ankyrin repeat SOCS_box PF07525.11 KFM05146.1 - 1.1e-11 44.3 0.5 2.2e-11 43.3 0.4 1.5 1 0 0 1 1 1 1 SOCS box PFK PF00365.15 KFM05147.1 - 7.7e-45 153.0 0.1 8.8e-45 152.8 0.1 1.0 1 0 0 1 1 1 1 Phosphofructokinase Peptidase_C48 PF02902.14 KFM05148.1 - 2.2e-48 164.7 1.4 3.8e-48 163.9 1.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C57 PF03290.8 KFM05148.1 - 0.00076 18.1 2.7 0.93 7.9 0.1 3.0 3 0 0 3 3 3 2 Vaccinia virus I7 processing peptidase COLFI PF01410.13 KFM05149.1 - 4.1e-54 183.2 0.0 4.4e-54 183.1 0.0 1.0 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain DUF1356 PF07092.7 KFM05150.1 - 2e-103 344.6 10.5 2.3e-103 344.5 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) LEA_2 PF03168.8 KFM05150.1 - 0.0097 16.2 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 1 Late embryogenesis abundant protein Amnionless PF14828.1 KFM05150.1 - 0.018 13.5 0.1 0.023 13.1 0.1 1.1 1 0 0 1 1 1 0 Amnionless Peptidase_A3 PF02160.10 KFM05150.1 - 0.069 12.7 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Cauliflower mosaic virus peptidase (A3) Vac7 PF12751.2 KFM05150.1 - 0.17 10.6 1.3 0.22 10.3 0.9 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 FAM196 PF15265.1 KFM05150.1 - 0.28 10.3 2.0 0.45 9.7 1.4 1.2 1 0 0 1 1 1 0 FAM196 family Hormone_recep PF00104.25 KFM05151.1 - 3.2e-29 101.4 1.3 5.2e-29 100.8 0.9 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFM05151.1 - 9.1e-29 99.5 16.0 1.5e-28 98.7 11.1 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Metallothio_5 PF02067.10 KFM05151.1 - 0.55 10.3 4.3 1.3 9.1 3.0 1.7 1 0 0 1 1 1 0 Metallothionein family 5 WD40 PF00400.27 KFM05152.1 - 1e-12 47.3 10.9 1.6e-05 24.6 0.0 6.6 6 1 1 7 7 7 3 WD domain, G-beta repeat eIF2A PF08662.6 KFM05152.1 - 7.2e-08 32.3 0.0 0.0041 16.8 0.0 3.5 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A DUF4613 PF15390.1 KFM05152.1 - 0.0002 19.7 7.3 0.011 13.9 2.4 2.7 2 1 1 3 3 3 2 Domain of unknown function (DUF4613) PD40 PF07676.7 KFM05152.1 - 0.0012 18.4 0.5 0.66 9.7 0.1 2.7 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 KFM05152.1 - 0.19 10.3 0.1 2.6 6.5 0.0 2.5 3 1 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region GSDH PF07995.6 KFM05153.1 - 2.1e-39 135.5 0.0 4e-39 134.6 0.0 1.4 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Folate_rec PF03024.9 KFM05153.1 - 7.8e-11 41.8 13.6 1.4e-10 41.0 9.4 1.3 1 0 0 1 1 1 1 Folate receptor family TAF1_subA PF14929.1 KFM05154.1 - 3.1e-87 293.3 26.3 1.1e-45 156.1 4.1 3.2 1 1 2 3 3 3 3 TAF RNA Polymerase I subunit A TPR_16 PF13432.1 KFM05154.1 - 0.05 14.2 0.1 0.24 12.1 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4298 PF14131.1 KFM05154.1 - 3.7 7.4 9.4 3.3 7.6 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4298) NPIP PF06409.6 KFM05155.1 - 8.8e-11 41.0 10.4 6.7e-08 31.6 6.5 2.6 2 0 0 2 2 2 2 Nuclear pore complex interacting protein (NPIP) SH3_2 PF07653.12 KFM05155.1 - 3e-09 36.2 0.2 1.8e-07 30.5 0.0 2.7 2 0 0 2 2 2 1 Variant SH3 domain DUF501 PF04417.7 KFM05155.1 - 4.2 7.2 22.8 0.056 13.2 0.1 4.2 2 1 1 3 3 3 0 Protein of unknown function (DUF501) Aida_C2 PF14186.1 KFM05156.1 - 2.6e-66 221.4 0.2 3.5e-66 221.0 0.1 1.1 1 0 0 1 1 1 1 Cytoskeletal adhesion Aida_N PF08910.5 KFM05156.1 - 2.7e-26 91.8 1.6 5.1e-26 90.9 1.1 1.5 1 0 0 1 1 1 1 Aida N-terminus BRO1 PF03097.13 KFM05157.1 - 4.5e-41 140.8 0.8 5.6e-41 140.5 0.6 1.0 1 0 0 1 1 1 1 BRO1-like domain Patched PF02460.13 KFM05158.1 - 2.1e-22 78.8 30.3 7.1e-16 57.3 6.2 2.5 2 0 0 2 2 2 2 Patched family MMPL PF03176.10 KFM05158.1 - 6.3e-14 51.4 23.1 9.5e-09 34.3 5.2 2.3 2 0 0 2 2 2 2 MMPL family Sterol-sensing PF12349.3 KFM05158.1 - 4.9e-11 42.3 15.7 4.9e-11 42.3 10.9 2.7 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Sushi PF00084.15 KFM05159.1 - 2.7e-36 123.6 23.9 1.9e-09 37.7 0.1 4.3 4 0 0 4 4 4 4 Sushi domain (SCR repeat) cEGF PF12662.2 KFM05159.1 - 0.01 15.4 11.5 2.7 7.7 0.1 4.8 4 0 0 4 4 4 0 Complement Clr-like EGF-like HRM PF02793.17 KFM05159.1 - 0.32 11.0 8.2 0.54 10.3 0.4 3.8 3 1 0 3 3 3 0 Hormone receptor domain Mei4 PF13971.1 KFM05160.1 - 8.3e-65 219.1 6.8 1e-64 218.8 4.7 1.0 1 0 0 1 1 1 1 Meiosis-specific protein Mei4 7tm_1 PF00001.16 KFM05161.1 - 3.4e-90 301.6 11.6 4.1e-90 301.3 8.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM05161.1 - 6.6e-11 41.8 10.4 5.9e-10 38.7 7.2 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM05161.1 - 6.7e-06 25.4 5.0 6.7e-06 25.4 3.4 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx SEA PF01390.15 KFM05162.1 - 1.1e-42 144.0 2.2 2.6e-20 72.1 0.2 2.5 2 0 0 2 2 2 2 SEA domain Myosin_head PF00063.16 KFM05163.1 - 1.8e-221 736.9 0.9 1.8e-221 736.9 0.6 2.1 2 0 0 2 2 2 1 Myosin head (motor domain) IQ PF00612.22 KFM05163.1 - 0.002 17.6 1.4 0.0057 16.1 1.0 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif Myosin_N PF02736.14 KFM05163.1 - 0.035 13.7 0.0 0.083 12.5 0.0 1.7 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain AAA_22 PF13401.1 KFM05163.1 - 0.67 10.1 0.0 0.67 10.1 0.0 3.4 3 1 0 3 3 3 0 AAA domain Peptidase_C48 PF02902.14 KFM05164.1 - 1.1e-33 116.6 3.5 5.8e-20 71.8 0.7 2.5 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain CortBP2 PF09727.4 KFM05165.1 - 8.6e-71 237.4 22.1 8.6e-71 237.4 15.3 7.0 3 2 4 7 7 7 2 Cortactin-binding protein-2 DUF3596 PF12167.3 KFM05165.1 - 0.034 13.6 0.5 0.15 11.5 0.3 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3596) Reo_sigmaC PF04582.7 KFM05165.1 - 1.4 8.0 28.1 0.37 9.9 2.5 4.3 2 2 3 5 5 5 0 Reovirus sigma C capsid protein CDC50 PF03381.10 KFM05166.1 - 2.7e-97 325.2 0.5 3.1e-97 325.0 0.3 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family fn3 PF00041.16 KFM05167.1 - 2.5e-247 799.8 86.6 1.3e-16 60.5 1.1 18.4 18 0 0 18 18 18 18 Fibronectin type III domain VWA PF00092.23 KFM05167.1 - 1.7e-199 656.5 14.3 1.9e-50 171.0 0.0 4.3 4 0 0 4 4 4 4 von Willebrand factor type A domain VWA_2 PF13519.1 KFM05167.1 - 5e-51 173.2 1.1 1.3e-12 48.1 0.1 4.4 4 0 0 4 4 4 4 von Willebrand factor type A domain Collagen PF01391.13 KFM05167.1 - 8.5e-34 114.9 175.3 2.6e-08 33.3 21.7 5.5 2 2 3 5 5 5 5 Collagen triple helix repeat (20 copies) Interfer-bind PF09294.5 KFM05167.1 - 3.9e-25 87.9 0.2 0.21 11.6 0.0 15.4 16 1 1 17 17 17 4 Interferon-alpha/beta receptor, fibronectin type III vWA-TerF-like PF10138.4 KFM05167.1 - 8.2e-09 35.5 4.4 0.024 14.4 0.4 3.8 4 0 0 4 4 4 3 vWA found in TerF C terminus SusE PF14292.1 KFM05167.1 - 0.00019 21.2 5.7 22 4.9 0.0 8.0 11 0 0 11 11 11 0 SusE outer membrane protein DUF2369 PF10179.4 KFM05167.1 - 0.00026 20.2 3.0 14 4.6 0.0 8.4 13 0 0 13 13 13 1 Uncharacterised conserved protein (DUF2369) Toxin_R_bind_N PF07953.7 KFM05167.1 - 0.0078 15.7 0.1 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Clostridium neurotoxin, N-terminal receptor binding CBM_4_9 PF02018.12 KFM05167.1 - 0.019 14.9 4.3 6.2 6.8 0.0 4.6 4 0 0 4 4 4 0 Carbohydrate binding domain MFS_1 PF07690.11 KFM05170.1 - 3.2e-58 197.1 34.9 4e-57 193.5 18.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFM05170.1 - 1.3e-07 30.6 24.9 1.2e-06 27.4 17.2 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter GTP_EFTU PF00009.22 KFM05171.1 - 1.1e-56 191.2 0.0 1.6e-56 190.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KFM05171.1 - 2.6e-36 123.7 0.0 7.6e-36 122.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KFM05171.1 - 1.6e-17 63.4 1.0 1.6e-17 63.4 0.7 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 KFM05171.1 - 3e-05 23.5 0.2 9.3e-05 21.9 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 KFM05171.1 - 0.00068 19.5 0.4 0.002 18.0 0.3 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KFM05171.1 - 0.048 13.4 0.1 8.5 6.1 0.1 2.4 2 0 0 2 2 2 0 Dynamin family GIDA PF01134.17 KFM05172.1 - 1.7e-97 326.7 0.0 2.4e-97 326.2 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 KFM05172.1 - 1.2e-19 70.1 0.0 2.6e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 GidA associated domain 3 Hexapep_2 PF14602.1 KFM05172.1 - 0.033 13.7 0.8 0.065 12.8 0.6 1.4 1 0 0 1 1 1 0 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.19 KFM05172.1 - 0.034 13.6 0.6 0.072 12.6 0.4 1.5 1 0 0 1 1 1 0 Bacterial transferase hexapeptide (six repeats) Mab-21 PF03281.9 KFM05173.1 - 3.1e-62 210.3 8.9 3.5e-62 210.1 6.2 1.0 1 0 0 1 1 1 1 Mab-21 protein DEAD PF00270.24 KFM05174.1 - 1.4e-35 122.2 0.0 8e-35 119.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFM05174.1 - 2.1e-26 91.5 0.1 1.8e-25 88.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain KH_1 PF00013.24 KFM05174.1 - 1.9e-08 33.8 0.1 6e-08 32.2 0.0 1.9 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 KFM05174.1 - 5.1e-07 29.1 0.6 1.2e-06 28.0 0.4 1.7 1 0 0 1 1 1 1 KH domain ResIII PF04851.10 KFM05174.1 - 0.0023 17.8 0.0 0.0064 16.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit KH_2 PF07650.12 KFM05174.1 - 0.0048 16.4 0.3 0.025 14.1 0.0 2.4 2 0 0 2 2 2 1 KH domain KH_5 PF13184.1 KFM05174.1 - 0.01 15.6 0.3 0.17 11.6 0.1 2.8 2 0 0 2 2 2 0 NusA-like KH domain SNF2_N PF00176.18 KFM05174.1 - 0.058 12.1 0.0 0.2 10.3 0.0 1.8 2 0 0 2 2 2 0 SNF2 family N-terminal domain KCNQ_channel PF03520.9 KFM05175.1 - 2.5e-91 304.5 1.1 5.4e-91 303.4 0.7 1.6 1 0 0 1 1 1 1 KCNQ voltage-gated potassium channel Ion_trans PF00520.26 KFM05175.1 - 1.1e-25 90.1 11.1 1.7e-25 89.4 7.7 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.11 KFM05175.1 - 1.6e-13 50.1 5.8 4.3e-13 48.7 4.0 1.7 1 0 0 1 1 1 1 Ion channel PKD_channel PF08016.7 KFM05175.1 - 0.063 11.6 3.5 0.026 12.9 0.6 1.6 1 1 1 2 2 2 0 Polycystin cation channel IQ PF00612.22 KFM05175.1 - 0.47 10.2 0.1 0.47 10.2 0.0 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif C2 PF00168.25 KFM05177.1 - 1.4e-34 117.7 0.0 3.1e-17 62.1 0.0 2.6 2 0 0 2 2 2 2 C2 domain PDZ PF00595.19 KFM05177.1 - 9.1e-11 41.7 0.0 2.1e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) FYVE_2 PF02318.11 KFM05177.1 - 3.5e-07 30.1 6.8 9.5e-07 28.7 4.7 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger Asparaginase_2 PF01112.13 KFM05178.1 - 3.1e-77 259.4 4.8 4.1e-77 259.0 3.3 1.1 1 0 0 1 1 1 1 Asparaginase Glyco_transf_43 PF03360.11 KFM05179.1 - 3.1e-39 134.6 0.1 3.5e-39 134.5 0.1 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 43 ArfGap PF01412.13 KFM05180.1 - 6.7e-33 112.9 0.2 6.7e-33 112.9 0.1 1.9 1 1 1 2 2 2 1 Putative GTPase activating protein for Arf DUF1674 PF07896.7 KFM05181.1 - 3.2e-18 65.6 6.1 4.9e-18 65.0 4.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) DUF676 PF05057.9 KFM05182.1 - 5.1e-61 205.7 0.0 9.5e-61 204.8 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF3657 PF12394.3 KFM05182.1 - 2.2e-29 101.2 6.2 3.1e-18 65.6 1.5 3.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3657) PGAP1 PF07819.8 KFM05182.1 - 2.7e-05 23.8 0.0 5.7e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.10 KFM05182.1 - 8.4e-05 21.7 0.0 0.00016 20.8 0.0 1.4 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase LMBR1 PF04791.11 KFM05183.1 - 8.4e-17 60.8 17.1 4.6e-16 58.4 1.3 2.6 2 1 1 3 3 3 2 LMBR1-like membrane protein DUF4294 PF14127.1 KFM05183.1 - 0.029 13.9 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4294) 7tm_2 PF00002.19 KFM05184.1 - 2.5e-62 210.1 15.0 3.5e-62 209.6 10.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF3497 PF12003.3 KFM05184.1 - 5.4e-49 166.4 0.0 8.4e-49 165.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3497) TSP_1 PF00090.14 KFM05184.1 - 1.3e-15 57.2 45.1 7.1e-11 42.0 10.8 3.1 3 0 0 3 3 3 2 Thrombospondin type 1 domain GPS PF01825.16 KFM05184.1 - 5.9e-15 55.1 2.6 5.9e-15 55.1 1.8 2.8 3 0 0 3 3 3 1 Latrophilin/CL-1-like GPS domain HRM PF02793.17 KFM05184.1 - 5.1e-08 32.8 0.4 5.1e-08 32.8 0.3 4.1 3 1 0 3 3 3 1 Hormone receptor domain NDUF_B12 PF08122.7 KFM05184.1 - 0.015 15.0 0.1 0.042 13.5 0.1 1.8 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B12 subunit family Dzip-like_N PF13815.1 KFM05187.1 - 1.9e-28 98.6 0.1 1.9e-28 98.6 0.1 5.7 3 2 3 6 6 6 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf-Di19 PF05605.7 KFM05187.1 - 0.11 12.6 7.0 0.26 11.4 0.8 2.8 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 KFM05187.1 - 0.75 10.2 8.2 0.42 11.0 2.8 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger DUF384 PF04064.8 KFM05187.1 - 0.85 9.2 5.4 0.35 10.4 0.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF384) SlyX PF04102.7 KFM05187.1 - 2.1 8.7 27.8 3 8.2 0.6 5.6 4 0 0 4 4 4 0 SlyX TPR_11 PF13414.1 KFM05188.1 - 3.5e-40 135.4 23.7 1.1e-11 44.1 0.7 6.3 4 2 2 6 6 6 6 TPR repeat TPR_2 PF07719.12 KFM05188.1 - 2e-30 102.1 24.2 0.0002 20.9 0.0 9.6 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.1 KFM05188.1 - 3.8e-30 103.8 12.4 2.8e-06 27.8 0.6 6.7 4 2 2 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.23 KFM05188.1 - 5.5e-29 98.5 24.4 6.2e-07 28.7 0.0 9.4 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 KFM05188.1 - 1.9e-24 85.7 21.4 1.7e-06 28.2 0.7 6.9 3 3 3 6 6 6 5 Tetratricopeptide repeat DnaJ PF00226.26 KFM05188.1 - 2.2e-22 78.5 4.8 1.1e-21 76.2 1.4 3.1 2 0 0 2 2 2 1 DnaJ domain TPR_14 PF13428.1 KFM05188.1 - 4e-20 70.4 11.3 0.022 15.3 0.0 9.9 4 3 6 10 10 10 4 Tetratricopeptide repeat TPR_8 PF13181.1 KFM05188.1 - 4.9e-19 66.6 23.9 9.8e-05 21.8 0.0 8.8 7 3 3 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.1 KFM05188.1 - 1.4e-16 60.0 10.1 6e-05 22.8 0.4 6.0 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 KFM05188.1 - 6.5e-15 54.0 10.1 0.00082 19.3 0.0 7.2 8 0 0 8 8 6 4 Tetratricopeptide repeat Apc3 PF12895.2 KFM05188.1 - 4.1e-13 49.2 26.1 2.5e-05 24.3 0.2 5.5 2 1 4 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KFM05188.1 - 4.9e-12 45.6 25.6 0.0022 17.8 0.2 7.4 1 1 5 7 7 7 6 Tetratricopeptide repeat TPR_6 PF13174.1 KFM05188.1 - 2.3e-11 43.3 18.9 0.077 13.4 0.0 9.7 9 2 1 10 10 9 2 Tetratricopeptide repeat TPR_20 PF14561.1 KFM05188.1 - 3.4e-09 36.6 22.6 0.074 13.1 0.0 7.5 4 2 3 7 7 7 2 Tetratricopeptide repeat TPR_21 PF09976.4 KFM05188.1 - 1.6e-08 34.6 21.4 1.3e-05 25.1 2.1 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFM05188.1 - 4.6e-07 29.1 17.3 4 7.4 0.0 8.7 7 2 1 8 8 8 1 Tetratricopeptide repeat TPR_15 PF13429.1 KFM05188.1 - 4e-05 22.8 15.0 0.07 12.1 0.2 5.4 1 1 3 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KFM05188.1 - 4.2e-05 23.3 9.1 0.25 11.2 0.3 5.9 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat COPI_C PF06957.6 KFM05188.1 - 0.0013 17.3 0.7 0.36 9.3 0.0 2.7 3 0 0 3 3 3 2 Coatomer (COPI) alpha subunit C-terminus DUF3887 PF13026.1 KFM05188.1 - 0.01 16.1 0.3 0.01 16.1 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3887) TPR_4 PF07721.9 KFM05188.1 - 0.026 14.9 8.3 1.1 9.8 0.0 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF4363 PF14276.1 KFM05188.1 - 0.05 13.2 0.1 0.05 13.2 0.1 3.6 5 0 0 5 5 4 0 Domain of unknown function (DUF4363) Virulence_fact PF13769.1 KFM05188.1 - 0.25 11.2 0.0 0.25 11.2 0.0 3.3 4 1 1 5 5 4 0 Virulence factor MAS20 PF02064.10 KFM05188.1 - 0.43 10.5 13.8 3.6 7.5 0.0 4.9 3 2 1 5 5 5 0 MAS20 protein import receptor Alkyl_sulf_dimr PF14863.1 KFM05188.1 - 0.84 9.8 9.7 0.69 10.1 0.3 4.1 1 1 2 4 4 4 0 Alkyl sulfatase dimerisation Sulfotransfer_2 PF03567.9 KFM05190.1 - 2.7e-50 171.4 1.3 2.7e-50 171.4 0.9 1.5 2 0 0 2 2 2 1 Sulfotransferase family Macoilin PF09726.4 KFM05191.1 - 0.0011 17.3 21.1 0.0022 16.3 14.6 1.5 1 1 0 1 1 1 1 Transmembrane protein Kelch_1 PF01344.20 KFM05192.1 - 3.9e-75 247.2 13.4 1.4e-14 53.3 0.0 6.7 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 KFM05192.1 - 7.1e-50 165.2 8.5 1.1e-09 38.0 0.0 6.4 2 2 4 6 6 6 6 Kelch motif BACK PF07707.10 KFM05192.1 - 6.1e-33 112.7 2.0 7.9e-33 112.3 0.0 2.3 3 0 0 3 3 3 1 BTB And C-terminal Kelch BTB PF00651.26 KFM05192.1 - 9.5e-32 109.2 1.8 1.1e-31 109.0 0.5 1.7 2 0 0 2 2 2 1 BTB/POZ domain Kelch_4 PF13418.1 KFM05192.1 - 2.3e-31 107.3 11.4 5.9e-06 25.9 0.0 6.4 4 2 2 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 KFM05192.1 - 6.7e-25 86.6 13.9 0.0016 18.5 0.1 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.10 KFM05192.1 - 8.6e-25 85.5 7.4 3.3e-06 26.6 0.0 7.0 7 0 0 7 7 7 5 Kelch motif Kelch_5 PF13854.1 KFM05192.1 - 1.1e-06 28.4 9.1 0.11 12.4 0.0 6.3 7 0 0 7 7 7 2 Kelch motif Phosducin PF02114.11 KFM05193.1 - 4.4e-115 382.9 2.6 4.7e-115 382.8 1.8 1.0 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 KFM05193.1 - 0.0021 17.7 0.0 0.004 16.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin ODR4-like PF14778.1 KFM05194.1 - 1.6e-108 362.6 0.7 1.9e-108 362.4 0.5 1.1 1 0 0 1 1 1 1 Olfactory receptor 4-like TPR_MLP1_2 PF07926.7 KFM05195.1 - 1e-29 102.9 28.4 1e-29 102.9 19.7 14.6 7 4 5 13 13 13 8 TPR/MLP1/MLP2-like protein GRP PF07172.6 KFM05195.1 - 7.4 7.1 8.9 83 3.7 6.2 3.0 1 0 0 1 1 1 0 Glycine rich protein family Kelch_1 PF01344.20 KFM05197.1 - 5.4e-84 275.5 8.8 5e-14 51.5 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 KFM05197.1 - 5.1e-54 178.3 4.5 1.4e-10 40.8 0.0 6.4 1 1 5 6 6 6 6 Kelch motif Kelch_3 PF13415.1 KFM05197.1 - 1.8e-42 142.5 7.9 4.3e-08 33.1 0.1 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.10 KFM05197.1 - 2.3e-37 125.3 1.5 6.6e-05 22.5 0.0 6.8 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.1 KFM05197.1 - 9.1e-37 124.5 4.4 4.3e-07 29.5 0.0 6.4 5 1 1 6 6 6 5 Galactose oxidase, central domain BTB PF00651.26 KFM05197.1 - 1.7e-26 92.4 0.5 2.6e-26 91.7 0.3 1.3 1 0 0 1 1 1 1 BTB/POZ domain Kelch_5 PF13854.1 KFM05197.1 - 2.9e-16 58.9 6.7 0.00051 19.9 0.0 6.2 6 0 0 6 6 6 4 Kelch motif BACK PF07707.10 KFM05197.1 - 8.1e-12 44.8 0.1 4e-11 42.6 0.0 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch VLPT PF07122.6 KFM05197.1 - 0.0014 18.2 0.6 0.17 11.5 1.0 2.6 2 0 0 2 2 2 1 Variable length PCR target protein (VLPT) PQQ_3 PF13570.1 KFM05197.1 - 0.016 15.4 3.8 0.31 11.3 0.1 4.0 4 0 0 4 4 4 0 PQQ-like domain Rax2 PF12768.2 KFM05197.1 - 0.064 12.4 0.2 0.42 9.7 0.0 2.3 2 0 0 2 2 2 0 Cortical protein marker for cell polarity DUF3141 PF11339.3 KFM05197.1 - 0.19 10.0 0.3 9 4.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3141) PIN_4 PF13638.1 KFM05198.1 - 8.2e-30 103.6 0.3 1.5e-28 99.5 0.1 2.4 2 0 0 2 2 2 1 PIN domain ABC_tran_2 PF12848.2 KFM05199.1 - 4.7 7.1 7.3 0.56 10.0 0.1 2.4 2 1 0 2 2 2 0 ABC transporter TRM PF02005.11 KFM05200.1 - 4e-69 233.3 5.9 4.8e-58 196.8 0.6 3.2 2 1 0 3 3 3 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 KFM05200.1 - 0.00012 21.7 0.5 0.00033 20.3 0.3 1.6 1 1 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.1 KFM05200.1 - 0.00039 20.0 0.1 0.002 17.7 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFM05200.1 - 0.04 13.3 0.1 0.075 12.4 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Cons_hypoth95 PF03602.10 KFM05200.1 - 0.052 12.9 0.0 0.2 11.0 0.0 2.0 1 1 0 1 1 1 0 Conserved hypothetical protein 95 zf-C3HC4 PF00097.20 KFM05201.1 - 4.7e-10 38.9 10.4 8.4e-10 38.1 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM05201.1 - 3.9e-09 36.1 8.2 6.5e-09 35.4 5.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFM05201.1 - 7.4e-08 32.2 9.3 1.2e-07 31.5 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM05201.1 - 1.1e-06 28.2 8.3 1.6e-06 27.6 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM05201.1 - 6.9e-06 25.6 8.7 1.2e-05 24.9 6.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFM05201.1 - 3e-05 23.7 8.3 6e-05 22.8 5.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 KFM05201.1 - 0.00012 21.5 5.9 0.0002 20.7 4.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 KFM05201.1 - 0.00032 20.2 7.3 0.00064 19.2 5.0 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 KFM05201.1 - 0.006 16.3 4.1 0.011 15.5 2.8 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-MIZ PF02891.15 KFM05201.1 - 0.018 14.5 7.3 0.031 13.7 5.0 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-UDP PF14569.1 KFM05201.1 - 0.029 14.0 0.9 0.092 12.5 0.6 1.9 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_UBOX PF13445.1 KFM05201.1 - 0.056 13.1 7.1 0.15 11.7 4.9 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.2 KFM05201.1 - 0.1 12.7 5.7 0.29 11.2 3.9 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger zf-Apc11 PF12861.2 KFM05201.1 - 0.18 11.6 2.5 0.35 10.7 1.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger CDC73 PF05179.9 KFM05201.1 - 0.32 10.3 1.9 0.49 9.7 1.3 1.2 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family zf-C4_Topoisom PF01396.14 KFM05201.1 - 0.73 9.3 3.8 0.21 11.0 0.5 1.7 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Glyco_hydro_47 PF01532.15 KFM05203.1 - 9.8e-139 462.8 0.0 1.3e-138 462.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.17 KFM05203.1 - 2.2e-15 56.1 0.0 4.1e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 PA domain DUF4612 PF15389.1 KFM05204.1 - 1.7e-20 73.7 3.1 1.8e-20 73.6 2.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4612) Sen15 PF09631.5 KFM05205.1 - 2.6e-25 88.5 0.0 3.3e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 Sen15 protein RNA_pol_Rpb5_C PF01191.14 KFM05205.1 - 0.049 13.2 0.1 0.09 12.3 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain Glyco_transf_25 PF01755.12 KFM05206.1 - 8.4e-40 136.5 0.0 1.1e-38 132.9 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Glyco_tranf_2_4 PF13704.1 KFM05206.1 - 3.7e-09 36.7 0.6 1.3e-08 35.0 0.1 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 Aminotran_4 PF01063.14 KFM05206.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class IV RasGEF PF00617.14 KFM05207.1 - 9e-62 208.1 1.7 1.7e-61 207.2 1.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KFM05207.1 - 7.9e-21 74.1 2.3 1.4e-20 73.3 0.1 2.6 3 0 0 3 3 3 1 RasGEF N-terminal motif RA PF00788.18 KFM05207.1 - 3e-14 53.2 0.1 2.9e-13 50.0 0.0 2.6 3 0 0 3 3 3 1 Ras association (RalGDS/AF-6) domain Acyl-CoA_ox_N PF14749.1 KFM05207.1 - 0.0012 19.1 1.1 1.7 8.9 0.1 3.4 3 0 0 3 3 3 2 Acyl-coenzyme A oxidase N-terminal APOBEC_N PF08210.6 KFM05208.1 - 5.5e-16 58.7 0.0 6.7e-16 58.4 0.0 1.0 1 0 0 1 1 1 1 APOBEC-like N-terminal domain P16-Arc PF04699.9 KFM05209.1 - 1.7e-40 138.5 0.1 1.8e-40 138.4 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.7 KFM05209.1 - 0.012 15.5 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Dip2/Utp12 Family SH3_1 PF00018.23 KFM05210.1 - 3.5e-27 93.5 0.1 9.8e-16 56.8 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 KFM05210.1 - 2.2e-23 81.5 0.1 3.4e-13 48.9 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain TPR_11 PF13414.1 KFM05210.1 - 3.8e-22 77.6 8.9 7.7e-11 41.4 1.1 3.3 1 1 2 3 3 3 3 TPR repeat SH3_2 PF07653.12 KFM05210.1 - 6.6e-18 63.9 0.0 1.1e-11 43.9 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain TPR_1 PF00515.23 KFM05210.1 - 2.4e-17 61.7 5.5 2.6e-06 26.7 0.1 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFM05210.1 - 5.1e-16 57.2 4.1 5.7e-05 22.7 0.2 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFM05210.1 - 1.1e-12 47.7 0.1 2.8e-07 30.3 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFM05210.1 - 3.9e-12 45.0 1.8 0.011 15.4 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFM05210.1 - 4.9e-08 32.2 0.4 0.06 13.1 0.0 4.0 2 1 1 3 3 3 3 Tetratricopeptide repeat PB1 PF00564.19 KFM05210.1 - 5.7e-08 32.3 0.0 1.1e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 PB1 domain TPR_17 PF13431.1 KFM05210.1 - 2.3e-06 27.3 0.0 0.068 13.3 0.0 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFM05210.1 - 5.8e-06 26.4 4.1 0.51 10.9 0.1 5.1 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFM05210.1 - 6.3e-06 25.9 0.4 0.0062 16.3 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFM05210.1 - 6.8e-05 23.1 0.3 0.4 11.4 0.0 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFM05210.1 - 9.8e-05 22.9 2.1 0.03 15.0 0.1 3.6 1 1 3 4 4 4 2 Tetratricopeptide repeat Cohesin_load PF10345.4 KFM05210.1 - 0.0028 15.9 1.3 0.0045 15.2 0.9 1.2 1 0 0 1 1 1 1 Cohesin loading factor Apc3 PF12895.2 KFM05210.1 - 0.016 15.2 4.3 9.5 6.4 0.1 3.5 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Phage_integrase PF00589.17 KFM05210.1 - 0.016 14.8 0.0 0.35 10.5 0.0 2.3 2 0 0 2 2 2 0 Phage integrase family TPR_10 PF13374.1 KFM05210.1 - 0.054 13.4 0.1 7.3 6.6 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat EST1_DNA_bind PF10373.4 KFM05211.1 - 4.9e-63 212.9 5.5 1.1e-62 211.8 3.8 1.6 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 KFM05211.1 - 2e-23 82.7 0.3 2e-23 82.7 0.2 2.9 3 0 0 3 3 3 1 Telomerase activating protein Est1 TPR_11 PF13414.1 KFM05211.1 - 1e-06 28.2 0.1 2.9e-06 26.8 0.1 1.7 1 0 0 1 1 1 1 TPR repeat zf-AD PF07776.10 KFM05211.1 - 0.003 17.5 0.6 0.012 15.6 0.4 2.1 1 1 0 1 1 1 1 Zinc-finger associated domain (zf-AD) TPR_12 PF13424.1 KFM05211.1 - 0.025 14.4 0.2 0.068 13.1 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 KFM05211.1 - 0.044 13.7 0.0 0.16 11.9 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFM05211.1 - 0.068 12.9 0.0 0.28 11.0 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.1 KFM05211.1 - 0.093 12.9 1.8 0.95 9.8 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFM05211.1 - 0.14 12.0 0.6 0.53 10.2 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat CTP_transf_2 PF01467.21 KFM05212.1 - 3.7e-22 79.0 0.0 7.4e-22 78.0 0.0 1.5 1 1 0 1 1 1 1 Cytidylyltransferase OB_NTP_bind PF07717.11 KFM05213.1 - 7.8e-15 54.7 0.0 1.2e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KFM05213.1 - 0.01 15.8 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Helicase associated domain (HA2) dsrm PF00035.20 KFM05214.1 - 1.5e-18 67.1 0.2 2.9e-11 43.7 0.1 2.9 2 0 0 2 2 2 2 Double-stranded RNA binding motif Helicase_C PF00271.26 KFM05214.1 - 2.2e-14 53.0 0.0 5.8e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFM05214.1 - 5.9e-08 32.3 0.1 2.3e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase HA2 PF04408.18 KFM05214.1 - 3.6e-06 26.9 0.1 1.3e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) AAA_19 PF13245.1 KFM05214.1 - 0.0018 17.9 0.0 0.0035 17.0 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 KFM05214.1 - 0.0037 17.1 0.0 0.02 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 KFM05214.1 - 0.0072 15.2 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_11 PF13086.1 KFM05214.1 - 0.021 14.3 0.1 0.89 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 KFM05214.1 - 0.028 13.5 0.0 0.068 12.2 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.1 KFM05214.1 - 0.03 14.4 0.1 0.13 12.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 KFM05214.1 - 0.059 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.10 KFM05214.1 - 0.082 12.7 0.3 1.6 8.5 0.0 2.7 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Dicer_dimer PF03368.9 KFM05214.1 - 0.1 12.4 0.0 0.39 10.5 0.0 2.0 1 0 0 1 1 1 0 Dicer dimerisation domain DHDPS PF00701.17 KFM05215.1 - 1.9e-47 161.2 0.0 2.2e-47 161.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family QCR10 PF09796.4 KFM05215.1 - 0.096 12.3 1.5 0.86 9.3 0.2 2.4 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) SOUL PF04832.7 KFM05216.1 - 2.3e-42 144.4 0.0 2.5e-42 144.3 0.0 1.0 1 0 0 1 1 1 1 SOUL heme-binding protein BTB PF00651.26 KFM05217.1 - 7.8e-27 93.4 0.3 1.4e-26 92.6 0.2 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 KFM05217.1 - 1.4e-15 56.6 16.5 6.1e-07 29.4 3.0 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFM05217.1 - 8.8e-12 44.6 20.7 2.8e-05 24.1 1.3 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM05217.1 - 2e-10 40.2 16.9 8.8e-05 22.5 0.5 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger DUF3342 PF11822.3 KFM05217.1 - 5.8e-05 22.3 0.2 5.8e-05 22.3 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) zf-C2H2_2 PF12756.2 KFM05217.1 - 0.00027 20.9 6.9 0.042 13.9 0.0 3.4 1 1 2 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KFM05217.1 - 0.00029 20.8 10.3 0.11 12.7 0.1 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM05217.1 - 0.0086 16.2 18.5 0.056 13.6 0.5 4.3 5 0 0 5 5 4 2 Zinc-finger of C2H2 type BTB_2 PF02214.17 KFM05217.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain Elf1 PF05129.8 KFM05217.1 - 0.37 10.4 2.8 0.3 10.8 0.4 2.0 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-DNA_Pol PF08996.5 KFM05217.1 - 0.45 9.8 3.4 1.9 7.7 0.3 2.2 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger zf-BED PF02892.10 KFM05217.1 - 0.81 9.4 16.6 2.1 8.2 0.2 3.6 2 1 0 2 2 2 0 BED zinc finger zf-trcl PF13451.1 KFM05217.1 - 1.3 8.7 4.8 2 8.1 1.1 2.6 2 1 1 3 3 3 0 Probable zinc-binding domain C1_1 PF00130.17 KFM05217.1 - 2 8.1 7.0 6.4 6.5 0.4 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_UBOX PF13445.1 KFM05218.1 - 8.3e-07 28.6 6.0 2.2e-06 27.2 4.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KFM05218.1 - 9.1e-06 25.4 5.1 2e-05 24.3 3.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KFM05218.1 - 9.4e-06 25.3 5.5 2.4e-05 24.0 3.8 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFM05218.1 - 1.3e-05 24.7 3.8 2.8e-05 23.6 2.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM05218.1 - 1.5e-05 24.8 6.6 3.3e-05 23.8 4.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM05218.1 - 2.2e-05 24.1 6.4 4.4e-05 23.1 4.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KFM05218.1 - 0.00014 21.4 7.2 0.00028 20.4 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 KFM05218.1 - 0.00014 21.4 3.3 0.00014 21.4 2.3 2.1 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) FYVE PF01363.16 KFM05218.1 - 0.001 18.9 1.4 0.0021 17.9 1.0 1.5 1 0 0 1 1 1 1 FYVE zinc finger Prok-RING_4 PF14447.1 KFM05218.1 - 0.0039 16.7 5.1 0.023 14.2 0.6 2.6 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.6 KFM05218.1 - 0.046 13.4 1.5 0.1 12.2 1.1 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.1 KFM05218.1 - 0.1 12.1 4.7 0.23 11.0 3.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 KFM05218.1 - 0.15 11.8 1.0 0.3 10.8 0.7 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein RabGAP-TBC PF00566.13 KFM05219.1 - 4.4e-57 193.0 5.2 4.4e-57 193.0 3.6 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF3694 PF12473.3 KFM05219.1 - 1.2e-37 128.7 0.0 2.6e-37 127.6 0.0 1.6 1 0 0 1 1 1 1 Kinesin protein CS PF04969.11 KFM05220.1 - 1.5e-14 54.2 0.8 3.5e-14 53.0 0.1 1.8 2 0 0 2 2 2 1 CS domain SGS PF05002.10 KFM05220.1 - 1.2e-13 50.5 3.8 3.3e-13 49.1 2.7 1.7 1 0 0 1 1 1 1 SGS domain Siah-Interact_N PF09032.6 KFM05220.1 - 7.6e-12 45.1 2.2 7.6e-12 45.1 1.5 2.5 2 0 0 2 2 2 1 Siah interacting protein, N terminal Ribosomal_S14 PF00253.16 KFM05221.1 - 1.4e-18 66.0 0.6 1.4e-18 66.0 0.4 1.6 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e Fibrinogen_C PF00147.13 KFM05222.1 - 1.1e-75 254.2 6.6 1.9e-75 253.4 4.6 1.4 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain fn3 PF00041.16 KFM05222.1 - 1.2e-75 249.6 19.7 7.1e-15 54.9 0.0 6.4 6 0 0 6 6 6 6 Fibronectin type III domain EGF_2 PF07974.8 KFM05222.1 - 3.9e-10 39.7 77.6 0.00012 22.1 9.9 5.1 4 1 1 5 5 5 3 EGF-like domain Interfer-bind PF09294.5 KFM05222.1 - 8.9e-08 32.1 5.4 1.6 8.7 0.0 6.3 6 0 0 6 6 6 3 Interferon-alpha/beta receptor, fibronectin type III DUF1410 PF07198.6 KFM05222.1 - 0.034 14.4 0.3 0.88 9.9 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1410) TSC22 PF01166.13 KFM05222.1 - 0.07 13.1 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family SusE PF14292.1 KFM05222.1 - 9.2 6.1 24.5 0.42 10.4 0.3 6.1 8 0 0 8 8 8 0 SusE outer membrane protein fn3 PF00041.16 KFM05223.1 - 2.4e-124 405.7 23.6 1.3e-15 57.2 0.0 9.3 9 0 0 9 9 9 9 Fibronectin type III domain Fibrinogen_C PF00147.13 KFM05223.1 - 1.1e-76 257.5 8.5 1.8e-76 256.8 5.9 1.4 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Interfer-bind PF09294.5 KFM05223.1 - 6.4e-11 42.2 0.0 8.1 6.5 0.0 8.1 8 0 0 8 8 8 2 Interferon-alpha/beta receptor, fibronectin type III hEGF PF12661.2 KFM05223.1 - 4.3e-09 35.8 33.2 0.016 15.2 0.7 6.1 5 0 0 5 5 5 4 Human growth factor-like EGF EGF_2 PF07974.8 KFM05223.1 - 3.9e-08 33.3 101.8 0.0024 18.0 8.4 6.3 6 1 0 6 6 6 4 EGF-like domain Uroplakin_II PF07353.7 KFM05223.1 - 0.01 15.2 2.9 0.79 9.0 0.1 4.5 7 0 0 7 7 7 0 Uroplakin II SusE PF14292.1 KFM05223.1 - 0.47 10.2 7.9 17 5.2 0.0 6.5 9 0 0 9 9 9 0 SusE outer membrane protein WD40 PF00400.27 KFM05224.1 - 1.9e-30 103.6 7.2 2.7e-06 27.0 0.0 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat zf-C3HC4 PF00097.20 KFM05224.1 - 4.8e-10 38.9 12.1 1.4e-09 37.4 8.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM05224.1 - 6.1e-10 38.9 11.3 2.1e-09 37.2 7.9 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM05224.1 - 2.9e-09 36.4 7.4 8.8e-09 34.9 5.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM05224.1 - 5e-09 35.8 9.3 5e-09 35.8 6.4 2.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KFM05224.1 - 1.1e-07 31.4 10.6 1.1e-07 31.4 7.4 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFM05224.1 - 4.2e-07 29.7 11.0 1.4e-06 28.0 7.6 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KFM05224.1 - 5.1e-05 22.9 7.7 0.00016 21.3 5.3 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 KFM05224.1 - 0.0043 16.6 10.0 0.018 14.6 7.1 2.0 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 KFM05224.1 - 0.22 11.6 14.3 0.03 14.4 5.6 2.6 2 1 0 2 2 2 0 RING-H2 zinc finger AAA_23 PF13476.1 KFM05224.1 - 1 9.6 6.0 2.6 8.3 4.2 1.6 1 0 0 1 1 1 0 AAA domain zf-Nse PF11789.3 KFM05224.1 - 4 7.0 11.6 0.44 10.1 4.4 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Notch PF00066.12 KFM05225.1 - 2.3e-17 62.9 45.7 4e-08 33.3 0.5 5.8 4 1 0 4 4 4 3 LNR domain Laminin_G_3 PF13385.1 KFM05225.1 - 3.6e-15 56.5 0.3 9.4e-15 55.1 0.3 1.7 2 0 0 2 2 1 1 Concanavalin A-like lectin/glucanases superfamily Peptidase_M43 PF05572.8 KFM05225.1 - 2.7e-13 49.7 0.4 6.8e-13 48.4 0.3 1.7 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Sushi PF00084.15 KFM05225.1 - 4e-09 36.6 61.1 2.9e-06 27.5 0.4 9.2 9 0 0 9 9 9 4 Sushi domain (SCR repeat) Reprolysin_2 PF13574.1 KFM05225.1 - 0.008 16.2 0.1 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 KFM05225.1 - 0.033 13.0 0.6 0.06 12.2 0.4 1.3 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_3 PF13582.1 KFM05225.1 - 0.055 13.9 0.8 0.11 12.9 0.6 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like fn3 PF00041.16 KFM05225.1 - 0.065 13.3 0.3 0.62 10.2 0.0 2.4 2 0 0 2 2 2 0 Fibronectin type III domain Peptidase_M57 PF12388.3 KFM05225.1 - 0.076 12.3 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Reprolysin_4 PF13583.1 KFM05225.1 - 0.12 11.8 2.9 0.38 10.2 2.0 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KFM05225.1 - 0.5 10.0 0.8 1 9.0 0.6 1.4 1 0 0 1 1 1 0 Matrixin FXa_inhibition PF14670.1 KFM05226.1 - 5.5e-12 45.5 33.5 2.9e-09 36.8 2.3 4.0 3 0 0 3 3 3 3 Coagulation Factor Xa inhibitory site MACPF PF01823.14 KFM05226.1 - 0.002 17.8 0.2 0.017 14.8 0.1 2.1 1 1 0 1 1 1 1 MAC/Perforin domain UPF0560 PF10577.4 KFM05226.1 - 0.035 12.3 0.0 0.051 11.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Tme5_EGF_like PF09064.5 KFM05226.1 - 5.3 6.7 15.9 0.011 15.3 2.1 3.1 3 0 0 3 3 3 0 Thrombomodulin like fifth domain, EGF-like EGF_3 PF12947.2 KFM05226.1 - 5.4 7.0 12.6 0.63 10.0 4.5 2.8 2 0 0 2 2 2 0 EGF domain MACPF PF01823.14 KFM05227.1 - 1.2e-05 25.1 0.0 2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 MAC/Perforin domain Sec16_C PF12931.2 KFM05228.1 - 3.9e-34 118.7 0.0 5.9e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 KFM05228.1 - 3.6e-18 65.6 0.0 6.1e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region DUF3498 PF12004.3 KFM05229.1 - 6.2e-176 586.3 42.8 1e-175 585.6 29.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3498) RasGAP PF00616.14 KFM05229.1 - 9.1e-42 142.9 0.4 9.1e-42 142.9 0.2 2.3 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase PH PF00169.24 KFM05229.1 - 6.7e-07 29.4 2.1 8e-06 25.9 0.0 3.5 3 1 0 3 3 3 1 PH domain C2 PF00168.25 KFM05229.1 - 1.7e-06 27.7 0.1 3.6e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 C2 domain PH_6 PF15406.1 KFM05229.1 - 0.08 13.0 0.0 0.27 11.2 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain YjgP_YjgQ PF03739.9 KFM05229.1 - 0.21 10.2 4.4 0.4 9.3 3.0 1.3 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family V_ATPase_I PF01496.14 KFM05229.1 - 0.82 7.4 6.9 1.5 6.6 4.8 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FliD_C PF07195.7 KFM05229.1 - 0.85 8.8 12.6 3.8 6.7 2.2 2.7 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus RasGEF PF00617.14 KFM05230.1 - 8.6e-54 182.1 0.0 2.1e-53 180.8 0.0 1.6 1 1 0 1 1 1 1 RasGEF domain PH PF00169.24 KFM05230.1 - 3.5e-05 23.9 0.1 7.8e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KFM05230.1 - 0.013 15.6 0.1 0.027 14.7 0.1 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Fibrinogen_C PF00147.13 KFM05231.1 - 1e-74 251.1 9.9 1.4e-74 250.6 6.9 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain zf-C4H2 PF10146.4 KFM05231.1 - 0.03 14.3 0.2 0.048 13.6 0.2 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein Fer4_NifH PF00142.13 KFM05231.1 - 0.21 10.7 1.1 0.32 10.1 0.8 1.2 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF2115 PF09888.4 KFM05231.1 - 0.35 10.9 5.5 0.54 10.3 3.8 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) DUF1193 PF06702.7 KFM05232.1 - 6.4e-91 303.6 0.0 8.5e-91 303.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1193) FAM198 PF15051.1 KFM05232.1 - 0.0017 17.1 0.0 0.0029 16.3 0.0 1.4 1 0 0 1 1 1 1 FAM198 protein Torsin PF06309.6 KFM05233.1 - 2.3e-47 160.0 0.5 3.8e-47 159.3 0.3 1.4 1 0 0 1 1 1 1 Torsin AAA_22 PF13401.1 KFM05233.1 - 4.1e-06 26.9 0.1 0.00016 21.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KFM05233.1 - 0.00016 21.8 0.0 0.00021 21.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KFM05233.1 - 0.002 18.2 0.0 0.003 17.6 0.0 1.3 1 0 0 1 1 1 1 RNA helicase PIF1 PF05970.9 KFM05233.1 - 0.0098 14.8 0.1 0.064 12.1 0.1 1.9 1 1 0 1 1 1 1 PIF1-like helicase AAA_2 PF07724.9 KFM05233.1 - 0.038 13.9 0.0 0.85 9.5 0.0 2.3 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) NACHT PF05729.7 KFM05233.1 - 0.046 13.3 0.1 0.12 12.0 0.1 1.7 1 1 0 1 1 1 0 NACHT domain NB-ARC PF00931.17 KFM05233.1 - 0.13 11.1 0.0 0.49 9.2 0.0 1.9 1 1 0 1 1 1 0 NB-ARC domain IstB_IS21 PF01695.12 KFM05233.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.1 KFM05233.1 - 0.15 12.8 0.0 0.26 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain Pkinase_Tyr PF07714.12 KFM05234.1 - 7.7e-98 326.6 0.0 1.2e-97 326.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM05234.1 - 1.2e-49 168.8 0.0 3.1e-49 167.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain F_actin_bind PF08919.5 KFM05234.1 - 2.8e-31 107.4 0.0 5.8e-31 106.4 0.0 1.6 1 0 0 1 1 1 1 F-actin binding SH2 PF00017.19 KFM05234.1 - 2e-24 85.2 0.1 4.7e-24 83.9 0.1 1.7 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.23 KFM05234.1 - 2.6e-12 45.9 0.0 4.8e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFM05234.1 - 2e-09 36.8 0.0 3.9e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFM05234.1 - 7.2e-08 31.8 0.0 1.4e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 KFM05234.1 - 3.7e-06 27.0 0.8 1.1e-05 25.5 0.6 1.8 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_6 PF12913.2 KFM05234.1 - 0.0057 15.8 0.0 0.012 14.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain of the SH3b1 type Kinase-like PF14531.1 KFM05234.1 - 0.0063 15.5 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFM05234.1 - 0.25 11.0 0.0 1.2 8.8 0.0 2.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family MBOAT PF03062.14 KFM05235.1 - 9.4e-46 156.4 37.3 1.3e-45 155.9 25.8 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Band_7 PF01145.20 KFM05236.1 - 1.5e-28 99.8 0.0 2.5e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 KFM05236.1 - 0.0012 18.3 0.2 0.0025 17.3 0.1 1.4 1 0 0 1 1 1 1 SPFH domain-Band 7 family Synapsin PF02078.11 KFM05236.1 - 0.14 12.2 0.1 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Synapsin, N-terminal domain OST-HTH PF12872.2 KFM05237.1 - 0.0004 20.1 0.0 0.0012 18.6 0.0 1.8 2 0 0 2 2 2 1 OST-HTH/LOTUS domain TUDOR PF00567.19 KFM05238.1 - 8.5e-13 48.2 0.3 1.8e-12 47.1 0.1 1.6 2 0 0 2 2 2 1 Tudor domain FAM163 PF15069.1 KFM05239.1 - 9.7e-47 159.1 0.1 1.1e-46 158.9 0.1 1.1 1 0 0 1 1 1 1 FAM163 family BSP_II PF05432.6 KFM05239.1 - 2.6e-05 23.6 2.6 3e-05 23.4 1.8 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) DUF4006 PF13179.1 KFM05239.1 - 0.0011 18.4 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF4006) DUF4366 PF14283.1 KFM05239.1 - 0.0037 16.7 0.2 0.0049 16.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) EphA2_TM PF14575.1 KFM05239.1 - 0.0046 17.3 0.0 0.007 16.7 0.0 1.2 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain IncA PF04156.9 KFM05239.1 - 0.0051 16.4 0.0 0.007 15.9 0.0 1.2 1 0 0 1 1 1 1 IncA protein Myc_N PF01056.13 KFM05239.1 - 0.0076 15.4 3.7 0.0098 15.0 2.5 1.2 1 0 0 1 1 1 1 Myc amino-terminal region FAM176 PF14851.1 KFM05239.1 - 0.0092 15.6 1.9 0.013 15.1 1.3 1.2 1 0 0 1 1 1 1 FAM176 family DUF1510 PF07423.6 KFM05239.1 - 0.023 14.0 0.1 0.031 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Pro-rich PF15240.1 KFM05239.1 - 0.032 14.3 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Proline-rich Ly49 PF08391.5 KFM05239.1 - 0.047 13.8 0.0 0.066 13.3 0.0 1.3 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region zf-C3HC4_3 PF13920.1 KFM05239.1 - 0.054 13.1 0.4 0.054 13.1 0.2 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CDV3 PF15359.1 KFM05239.1 - 0.061 13.3 1.3 0.11 12.5 0.9 1.4 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 E7 PF00527.13 KFM05239.1 - 0.088 12.9 4.3 0.2 11.8 3.0 1.6 1 0 0 1 1 1 0 E7 protein, Early protein DUF3530 PF12048.3 KFM05239.1 - 0.14 11.1 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DUF3169 PF11368.3 KFM05239.1 - 0.16 11.1 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Nucleoplasmin PF03066.10 KFM05239.1 - 0.16 11.4 10.8 0.25 10.8 7.5 1.3 1 0 0 1 1 1 0 Nucleoplasmin TRAP_alpha PF03896.11 KFM05239.1 - 0.28 10.1 1.3 0.36 9.7 0.9 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CENP-B_dimeris PF09026.5 KFM05239.1 - 0.32 11.2 10.2 0.46 10.7 7.0 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2890 PF11081.3 KFM05239.1 - 0.5 10.4 8.2 0.65 10.0 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) CIAPIN1 PF05093.8 KFM05239.1 - 0.51 10.4 6.3 0.97 9.5 4.3 1.4 1 0 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Radial_spoke PF04712.7 KFM05239.1 - 0.81 8.3 10.6 1 8.0 7.4 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Daxx PF03344.10 KFM05239.1 - 1.3 7.3 10.3 1.7 7.0 7.1 1.1 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 KFM05239.1 - 1.4 7.5 7.9 1.9 7.1 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) VID27 PF08553.5 KFM05239.1 - 1.5 6.9 6.7 1.9 6.6 4.6 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein CDC45 PF02724.9 KFM05239.1 - 1.6 6.6 3.6 2 6.3 2.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 KFM05239.1 - 2.2 6.0 7.5 2.7 5.8 5.2 1.0 1 0 0 1 1 1 0 Nop14-like family Brevenin PF03032.10 KFM05239.1 - 2.6 7.9 15.2 3.9 7.3 10.6 1.3 1 0 0 1 1 1 0 Brevenin/esculentin/gaegurin/rugosin family Paf1 PF03985.8 KFM05239.1 - 7.1 5.2 9.1 8.8 4.9 6.3 1.1 1 0 0 1 1 1 0 Paf1 TSP_1 PF00090.14 KFM05240.1 - 4e-27 94.0 119.0 6e-07 29.4 5.7 9.4 8 1 0 8 8 8 7 Thrombospondin type 1 domain ADAM_spacer1 PF05986.9 KFM05240.1 - 1.7e-24 85.8 0.0 2.6e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 PLAC PF08686.6 KFM05240.1 - 7.3e-11 42.1 9.7 7.3e-11 42.1 6.7 3.1 2 0 0 2 2 2 1 PLAC (protease and lacunin) domain LAP1C PF05609.7 KFM05241.1 - 3.9e-92 309.3 0.1 4.3e-92 309.2 0.1 1.0 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) Mito_morph_reg PF14972.1 KFM05241.1 - 0.057 12.8 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial morphogenesis regulator LAP1C PF05609.7 KFM05242.1 - 5.6e-95 318.7 0.0 6.2e-95 318.5 0.0 1.0 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) Nic96 PF04097.9 KFM05242.1 - 0.088 10.9 0.5 1.5 6.8 0.1 2.0 2 0 0 2 2 2 0 Nup93/Nic96 CAP_GLY PF01302.20 KFM05243.1 - 7.6e-21 73.5 0.1 1.3e-20 72.8 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain Evr1_Alr PF04777.8 KFM05244.1 - 5.6e-27 93.4 0.2 1.5e-26 92.0 0.1 1.8 2 0 0 2 2 2 1 Erv1 / Alr family Thioredoxin PF00085.15 KFM05244.1 - 0.00012 21.6 0.0 0.0011 18.5 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin DUF3330 PF11809.3 KFM05244.1 - 0.018 14.8 0.3 0.66 9.8 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3330) Thioredoxin_2 PF13098.1 KFM05244.1 - 0.036 14.2 0.0 27 5.0 0.0 3.4 3 0 0 3 3 3 0 Thioredoxin-like domain Zn-ribbon_8 PF09723.5 KFM05244.1 - 0.36 10.8 3.0 18 5.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain LIM PF00412.17 KFM05245.1 - 1.8e-32 111.1 19.6 1.1e-16 60.5 2.1 2.2 2 0 0 2 2 2 2 LIM domain Homeobox PF00046.24 KFM05245.1 - 2.1e-21 75.2 2.4 3.5e-21 74.5 1.7 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFM05245.1 - 0.00013 21.6 0.0 0.00029 20.4 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain PSP1 PF04468.7 KFM05245.1 - 0.071 13.0 0.1 0.26 11.2 0.1 2.0 1 1 0 1 1 1 0 PSP1 C-terminal conserved region Orbi_VP3 PF01700.11 KFM05245.1 - 0.13 9.6 0.0 0.18 9.2 0.0 1.0 1 0 0 1 1 1 0 Orbivirus VP3 (T2) protein PHF5 PF03660.9 KFM05245.1 - 0.52 10.3 9.8 0.037 14.0 2.0 2.2 1 1 1 2 2 2 0 PHF5-like protein zf-RING_5 PF14634.1 KFM05245.1 - 4.8 6.9 0.0 4.8 6.9 0.0 3.6 2 1 0 2 2 2 0 zinc-RING finger domain DUF164 PF02591.10 KFM05245.1 - 7.9 6.3 10.0 9.9 6.0 1.1 2.8 2 0 0 2 2 2 0 Putative zinc ribbon domain Ank_4 PF13637.1 KFM05246.1 - 1.6e-21 76.2 1.2 3.6e-14 52.8 0.1 2.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KFM05246.1 - 4.7e-21 74.9 0.1 7.4e-21 74.2 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFM05246.1 - 2.8e-20 71.0 0.4 4.9e-09 35.5 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KFM05246.1 - 1.1e-18 66.7 0.2 1.7e-11 43.9 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM05246.1 - 1.6e-14 52.5 0.4 5.4e-06 26.1 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat ACBP PF00887.14 KFM05246.1 - 3e-14 52.4 0.1 5.1e-14 51.6 0.1 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein GBP_repeat PF02526.9 KFM05246.1 - 0.12 11.8 0.0 4.6 6.7 0.0 2.9 3 0 0 3 3 3 0 Glycophorin-binding protein EXS PF03124.9 KFM05247.1 - 4.2e-116 387.7 22.5 6.1e-116 387.2 15.6 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.14 KFM05247.1 - 9.3e-22 78.0 11.6 9.3e-22 78.0 8.0 2.6 3 1 0 3 3 3 1 SPX domain DUF1154 PF06631.6 KFM05247.1 - 0.12 12.0 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1154) Syntaxin-6_N PF09177.6 KFM05249.1 - 2e-26 92.2 2.2 4.6e-26 91.0 0.1 2.3 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 KFM05249.1 - 6.1e-16 57.8 2.6 1.7e-15 56.4 1.8 1.8 1 0 0 1 1 1 1 SNARE domain DUF3753 PF12575.3 KFM05249.1 - 0.027 14.2 1.8 0.057 13.2 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) UPF0184 PF03670.8 KFM05249.1 - 0.036 14.2 0.3 0.84 9.8 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) FliD_C PF07195.7 KFM05249.1 - 0.04 13.2 1.9 1.4 8.1 0.0 2.6 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus TBPIP PF07106.8 KFM05249.1 - 0.048 13.2 0.4 0.048 13.2 0.3 2.2 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fusion_gly PF00523.13 KFM05249.1 - 0.055 11.5 0.2 0.1 10.6 0.1 1.4 1 0 0 1 1 1 0 Fusion glycoprotein F0 DUF4492 PF14899.1 KFM05249.1 - 0.23 10.9 3.2 0.57 9.7 2.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) Syntaxin PF00804.20 KFM05249.1 - 0.28 11.3 6.5 0.22 11.6 0.2 2.8 1 1 1 2 2 2 0 Syntaxin DUF342 PF03961.8 KFM05249.1 - 0.43 8.9 2.9 5.9 5.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF342) DUF2937 PF11157.3 KFM05249.1 - 0.78 9.0 4.0 2.7 7.3 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2937) GP41 PF00517.12 KFM05249.1 - 1.2 8.6 8.4 4.4 6.8 0.4 2.6 1 1 1 2 2 2 0 Retroviral envelope protein Cortex-I_coil PF09304.5 KFM05249.1 - 6.3 6.8 10.1 6.8 6.7 0.6 2.4 2 1 0 2 2 2 0 Cortexillin I, coiled coil zf-H2C2_2 PF13465.1 KFM05251.1 - 3.3e-40 134.4 43.1 9.8e-08 31.9 1.9 7.3 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.21 KFM05251.1 - 1.1e-30 104.1 39.4 3e-05 24.0 2.1 7.1 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM05251.1 - 3.1e-25 86.5 36.0 0.00026 21.1 1.4 7.1 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM05251.1 - 7.7e-15 54.5 17.5 0.32 11.1 0.1 7.3 7 0 0 7 7 7 5 Zinc-finger double-stranded RNA-binding zf-RING_3 PF14369.1 KFM05251.1 - 3e-10 39.9 16.2 0.037 14.0 0.3 6.2 5 1 1 6 6 6 3 zinc-finger Zn-ribbon_8 PF09723.5 KFM05251.1 - 7.1e-09 35.4 26.5 0.34 10.8 0.1 6.8 6 1 0 6 6 6 3 Zinc ribbon domain zf-C2H2_6 PF13912.1 KFM05251.1 - 3e-08 33.2 31.5 0.16 11.9 0.5 7.4 7 0 0 7 7 7 2 C2H2-type zinc finger zf-Di19 PF05605.7 KFM05251.1 - 5.1e-07 29.7 22.0 0.00079 19.4 0.5 4.7 3 2 1 5 5 5 4 Drought induced 19 protein (Di19), zinc-binding C1_1 PF00130.17 KFM05251.1 - 3.1e-05 23.6 14.9 0.11 12.2 0.5 4.8 4 3 1 5 5 5 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 KFM05251.1 - 4.6e-05 23.0 10.5 11 5.7 0.0 6.2 6 0 0 6 6 6 0 Prokaryotic RING finger family 1 DZR PF12773.2 KFM05251.1 - 0.0026 17.5 19.8 1.3e+04 -4.0 13.8 4.3 1 1 0 1 1 0 0 Double zinc ribbon Ribosomal_L44 PF00935.14 KFM05251.1 - 0.0037 17.2 15.6 0.043 13.8 0.8 4.9 3 1 3 6 6 6 2 Ribosomal protein L44 C1_3 PF07649.7 KFM05251.1 - 0.015 15.3 18.4 10 6.2 0.0 6.1 6 0 0 6 6 6 0 C1-like domain zf-met PF12874.2 KFM05251.1 - 0.015 15.4 17.3 1.4 9.2 0.0 6.1 6 0 0 6 6 6 0 Zinc-finger of C2H2 type Rad50_zn_hook PF04423.9 KFM05251.1 - 0.023 14.1 8.5 1.9 8.0 0.3 4.4 4 1 0 4 4 4 0 Rad50 zinc hook motif zf-ISL3 PF14690.1 KFM05251.1 - 0.032 14.2 21.2 4.1 7.4 0.2 6.4 6 0 0 6 6 6 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn_ribbon_recom PF13408.1 KFM05251.1 - 0.036 14.3 19.4 3.2 8.0 2.8 4.8 3 1 1 4 4 4 0 Recombinase zinc beta ribbon domain DUF2225 PF09986.4 KFM05251.1 - 0.039 13.4 11.8 1 8.8 0.1 4.0 3 2 2 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2225) C1_4 PF07975.7 KFM05251.1 - 0.039 13.9 21.6 7.3 6.6 2.6 5.3 2 2 4 6 6 6 0 TFIIH C1-like domain zf-IS66 PF13005.2 KFM05251.1 - 0.043 13.8 22.5 5.8 6.9 0.0 6.5 6 1 0 6 6 6 0 zinc-finger binding domain of transposase IS66 DUF164 PF02591.10 KFM05251.1 - 0.053 13.3 15.5 4.4 7.2 0.4 5.6 5 1 1 6 6 6 0 Putative zinc ribbon domain zf-trcl PF13451.1 KFM05251.1 - 0.057 13.0 19.2 0.94 9.1 0.1 5.6 5 2 0 5 5 5 0 Probable zinc-binding domain FYVE PF01363.16 KFM05251.1 - 0.061 13.2 23.6 2.7 7.9 2.2 5.5 1 1 4 5 5 5 0 FYVE zinc finger zf-H2C2_5 PF13909.1 KFM05251.1 - 0.065 13.4 1.9 0.065 13.4 1.3 7.8 8 2 0 8 8 6 0 C2H2-type zinc-finger domain FYDLN_acid PF09538.5 KFM05251.1 - 0.086 13.4 9.0 16 6.1 0.0 4.9 1 1 3 4 4 4 0 Protein of unknown function (FYDLN_acid) Zn_Tnp_IS1595 PF12760.2 KFM05251.1 - 0.14 11.9 28.9 0.7 9.7 1.9 4.2 2 2 2 4 4 4 0 Transposase zinc-ribbon domain NADH-G_4Fe-4S_3 PF10588.4 KFM05251.1 - 0.23 10.7 5.7 4.5 6.5 0.3 3.8 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region zf-C2H2_2 PF12756.2 KFM05251.1 - 0.5 10.5 17.9 6 7.0 0.3 5.6 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 KFM05251.1 - 0.5 10.0 16.7 1.6 8.4 0.1 5.4 6 0 0 6 6 6 0 zinc-finger of a C2HC-type HypA PF01155.14 KFM05251.1 - 0.54 9.9 14.7 17 5.1 2.4 3.9 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family E6 PF00518.12 KFM05251.1 - 0.66 10.3 4.4 12 6.3 0.0 3.2 2 1 1 4 4 3 0 Early Protein (E6) Evr1_Alr PF04777.8 KFM05251.1 - 0.97 9.3 17.5 2.8 7.9 0.1 5.1 1 1 3 4 4 4 0 Erv1 / Alr family Rep_fac-A_C PF08646.5 KFM05251.1 - 1.3 8.7 15.7 14 5.4 1.2 4.6 1 1 4 5 5 5 0 Replication factor-A C terminal domain zf-met2 PF12907.2 KFM05251.1 - 1.7 8.7 12.8 28 4.7 0.0 5.3 6 1 0 6 6 5 0 Zinc-binding OrfB_Zn_ribbon PF07282.6 KFM05251.1 - 2 8.1 22.1 12 5.6 1.2 5.4 3 1 3 6 6 6 0 Putative transposase DNA-binding domain zf-AN1 PF01428.11 KFM05251.1 - 2.3 8.1 27.3 13 5.7 0.6 6.3 5 1 1 6 6 6 0 AN1-like Zinc finger Zn_ribbon_2 PF12674.2 KFM05251.1 - 2.8 8.3 7.2 3.4 8.0 0.2 3.5 3 1 0 4 4 4 0 Putative zinc ribbon domain IBR PF01485.16 KFM05251.1 - 2.9 7.8 20.2 86 3.1 0.3 4.9 1 1 1 2 2 1 0 IBR domain zf-FPG_IleRS PF06827.9 KFM05251.1 - 3.1 7.5 16.8 8.8 6.0 0.0 5.4 6 0 0 6 6 5 0 Zinc finger found in FPG and IleRS BolA PF01722.13 KFM05251.1 - 3.2 7.7 6.6 78 3.3 0.2 3.7 2 2 3 5 5 5 0 BolA-like protein Rubredoxin PF00301.15 KFM05251.1 - 3.3 7.6 18.5 12 5.8 0.0 5.4 5 1 0 5 5 5 0 Rubredoxin CpXC PF14353.1 KFM05251.1 - 5.1 7.0 21.0 14 5.6 0.1 5.6 2 2 3 6 6 6 0 CpXC protein zf-CHCC PF10276.4 KFM05251.1 - 5.2 7.0 16.9 1 9.2 0.2 4.7 5 0 0 5 5 4 0 Zinc-finger domain Ribosomal_L37ae PF01780.14 KFM05251.1 - 5.8 6.8 19.2 12 5.8 0.0 5.5 2 2 3 5 5 5 0 Ribosomal L37ae protein family Pox_A3L PF05288.6 KFM05251.1 - 6 6.6 6.6 23 4.7 0.0 3.6 4 0 0 4 4 3 0 Poxvirus A3L Protein GAGA PF09237.6 KFM05251.1 - 9.2 5.9 15.7 9.9 5.8 0.0 4.6 1 1 5 6 6 6 0 GAGA factor SAE2 PF08573.5 KFM05251.1 - 9.8 6.9 10.9 33 5.2 2.1 4.1 1 1 1 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus zf-H2C2_2 PF13465.1 KFM05252.1 - 3.3e-48 159.6 46.0 1.4e-07 31.4 0.1 9.0 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.21 KFM05252.1 - 5.6e-39 130.1 45.0 1.7e-05 24.8 0.1 8.1 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM05252.1 - 4.8e-18 64.0 47.6 0.004 17.3 1.9 8.2 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM05252.1 - 2.9e-12 46.0 29.2 1.3 9.0 0.0 8.6 8 1 0 8 8 8 5 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 KFM05252.1 - 9.5e-06 25.4 32.3 1.2 9.1 0.5 7.8 4 3 1 5 5 5 3 Zinc ribbon domain zf-LYAR PF08790.6 KFM05252.1 - 1.6e-05 24.5 20.9 2.6 7.8 0.0 7.8 8 0 0 8 8 8 2 LYAR-type C2HC zinc finger C1_1 PF00130.17 KFM05252.1 - 2.5e-05 23.8 12.0 0.35 10.6 0.0 5.1 2 2 4 6 6 6 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-Di19 PF05605.7 KFM05252.1 - 8.6e-05 22.5 36.2 0.00091 19.3 0.5 6.1 3 1 2 6 6 6 3 Drought induced 19 protein (Di19), zinc-binding FYDLN_acid PF09538.5 KFM05252.1 - 0.00013 22.4 17.3 12 6.5 0.0 7.3 1 1 7 8 8 8 0 Protein of unknown function (FYDLN_acid) HypA PF01155.14 KFM05252.1 - 0.0012 18.5 15.2 1.4 8.6 0.5 4.3 1 1 2 3 3 3 2 Hydrogenase expression/synthesis hypA family zf-AN1 PF01428.11 KFM05252.1 - 0.0016 18.3 27.7 5.6 6.9 0.1 8.0 7 1 1 8 8 8 0 AN1-like Zinc finger DUF1610 PF07754.6 KFM05252.1 - 0.003 17.6 1.8 0.003 17.6 1.2 7.4 8 0 0 8 8 7 3 Domain of unknown function (DUF1610) Zn_Tnp_IS1595 PF12760.2 KFM05252.1 - 0.0055 16.4 34.2 0.29 10.9 0.7 5.7 3 2 3 6 6 6 3 Transposase zinc-ribbon domain Elf1 PF05129.8 KFM05252.1 - 0.013 15.1 23.3 0.08 12.6 0.2 5.0 1 1 3 5 5 5 0 Transcription elongation factor Elf1 like zf-CSL PF05207.8 KFM05252.1 - 0.019 14.4 20.5 0.097 12.1 0.5 5.8 2 2 2 4 4 4 0 CSL zinc finger zinc_ribbon_4 PF13717.1 KFM05252.1 - 0.022 14.4 29.1 0.057 13.1 0.4 7.3 7 1 0 7 7 7 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 KFM05252.1 - 0.026 14.1 30.9 0.052 13.1 0.6 7.4 7 1 0 7 7 7 0 zinc-ribbon domain RRN7 PF11781.3 KFM05252.1 - 0.044 13.2 11.9 1.1 8.8 0.0 6.0 7 0 0 7 7 7 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C2H2_jaz PF12171.3 KFM05252.1 - 0.077 13.1 1.1 0.077 13.1 0.7 7.2 9 0 0 9 9 8 0 Zinc-finger double-stranded RNA-binding LIM PF00412.17 KFM05252.1 - 0.11 12.6 20.2 1.1 9.3 0.4 4.9 5 2 0 5 5 4 0 LIM domain zf-C2HC_2 PF13913.1 KFM05252.1 - 0.14 11.8 0.2 0.14 11.8 0.1 7.1 7 0 0 7 7 7 0 zinc-finger of a C2HC-type PhnA_Zn_Ribbon PF08274.7 KFM05252.1 - 0.17 11.6 18.1 28 4.6 0.1 6.4 6 1 0 6 6 6 0 PhnA Zinc-Ribbon zf-trcl PF13451.1 KFM05252.1 - 0.25 10.9 25.4 1.3 8.7 1.0 6.4 5 3 0 5 5 5 0 Probable zinc-binding domain UPF0547 PF10571.4 KFM05252.1 - 0.39 10.4 43.7 0.39 10.4 0.6 7.9 8 0 0 8 8 8 0 Uncharacterised protein family UPF0547 TFIIS_C PF01096.13 KFM05252.1 - 0.49 10.0 25.0 22 4.7 0.0 7.6 8 0 0 8 8 8 0 Transcription factor S-II (TFIIS) zf-RING_3 PF14369.1 KFM05252.1 - 0.78 9.7 31.5 12 5.9 0.1 7.4 8 0 0 8 8 8 0 zinc-finger C1_4 PF07975.7 KFM05252.1 - 0.93 9.5 24.8 14 5.7 1.1 6.1 3 3 2 6 6 6 0 TFIIH C1-like domain GAGA PF09237.6 KFM05252.1 - 1.3 8.6 17.2 2.6 7.6 0.0 5.5 3 3 3 6 6 6 0 GAGA factor zf-RING_UBOX PF13445.1 KFM05252.1 - 2.1 8.1 10.7 4.6 7.0 0.7 3.1 3 0 0 3 3 2 0 RING-type zinc-finger zf-ISL3 PF14690.1 KFM05252.1 - 2.7 8.1 32.0 0.97 9.5 0.1 7.6 8 0 0 8 8 8 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 XPA_N PF01286.13 KFM05252.1 - 3.8 7.2 22.4 9.6 5.9 0.1 6.7 7 0 0 7 7 7 0 XPA protein N-terminal zf-IS66 PF13005.2 KFM05252.1 - 4.4 7.3 26.9 29 4.7 0.1 7.5 8 0 0 8 8 7 0 zinc-finger binding domain of transposase IS66 zinc-ribbons_6 PF07191.7 KFM05252.1 - 4.9 7.0 21.1 14 5.5 0.2 5.7 3 2 2 5 5 5 0 zinc-ribbons NOA36 PF06524.7 KFM05252.1 - 7.7 5.6 20.9 1.1 8.5 1.3 3.5 1 1 2 3 3 3 0 NOA36 protein Gln-synt_C PF00120.19 KFM05253.1 - 3.2e-65 219.8 0.0 4e-65 219.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 KFM05253.1 - 3.9e-21 74.4 0.0 6.4e-21 73.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain RGS PF00615.14 KFM05254.1 - 5.9e-09 36.0 0.1 5.8e-05 23.1 0.1 3.1 3 0 0 3 3 3 2 Regulator of G protein signaling domain TMEM95 PF15203.1 KFM05254.1 - 0.035 13.5 0.5 0.12 11.7 0.1 1.9 2 0 0 2 2 2 0 TMEM95 family Ank_2 PF12796.2 KFM05256.1 - 6.5e-51 170.6 16.3 1.5e-13 50.9 0.2 4.8 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KFM05256.1 - 8.2e-43 142.1 3.4 9.8e-06 25.1 0.0 8.6 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.1 KFM05256.1 - 1.6e-38 130.3 5.8 1.2e-07 32.0 0.1 7.3 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM05256.1 - 8.3e-31 102.9 2.3 0.0041 17.2 0.0 8.8 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.1 KFM05256.1 - 1.8e-30 104.2 3.9 1.5e-05 25.0 0.0 6.0 2 2 3 6 6 6 6 Ankyrin repeats (many copies) Ribonuc_2-5A PF06479.7 KFM05256.1 - 7.7e-13 48.4 0.3 3.3e-12 46.3 0.2 2.2 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.20 KFM05256.1 - 6.7e-12 45.1 0.0 1.9e-11 43.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.9 KFM05256.1 - 1e-06 28.0 0.1 2.4e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 KFM05256.1 - 0.0007 18.7 0.0 0.0012 17.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM05256.1 - 0.0029 16.5 0.0 0.0059 15.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DUF3322 PF11795.3 KFM05256.1 - 0.019 14.6 0.0 2.1 7.9 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) Shigella_OspC PF06128.6 KFM05256.1 - 0.035 13.6 0.6 4.5 6.6 0.0 2.7 2 1 0 2 2 2 0 Shigella flexneri OspC protein RGS PF00615.14 KFM05257.1 - 1.8e-37 128.0 4.1 2.1e-37 127.7 2.9 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS PF00615.14 KFM05258.1 - 2e-38 131.1 2.4 2.7e-38 130.6 1.7 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain DNA_gyraseB_C PF00986.16 KFM05258.1 - 0.12 12.1 0.0 8.9 6.1 0.0 2.3 2 0 0 2 2 2 0 DNA gyrase B subunit, carboxyl terminus tRNA-synt_2 PF00152.15 KFM05259.1 - 3.5e-110 367.9 0.0 4.4e-110 367.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) GAD PF02938.9 KFM05259.1 - 4.1e-14 52.5 0.0 1.1e-13 51.1 0.0 1.7 2 0 0 2 2 2 1 GAD domain tRNA_anti-codon PF01336.20 KFM05259.1 - 1.6e-06 27.8 0.0 3.1e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 KFM05259.1 - 0.0012 18.4 0.6 0.29 10.7 0.3 3.1 2 1 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) CENP-L PF13092.1 KFM05260.1 - 9e-37 126.3 0.0 1.4e-36 125.7 0.0 1.3 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Kelch_1 PF01344.20 KFM05261.1 - 6.7e-91 297.6 13.7 5e-17 61.1 0.2 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 KFM05261.1 - 1.6e-56 186.2 6.5 6.5e-10 38.7 0.0 6.3 1 1 5 6 6 6 6 Kelch motif Kelch_4 PF13418.1 KFM05261.1 - 1.4e-40 136.7 5.9 2.2e-07 30.5 0.0 6.3 3 1 3 6 6 6 6 Galactose oxidase, central domain BACK PF07707.10 KFM05261.1 - 6.5e-38 128.7 0.3 1.3e-37 127.7 0.0 1.7 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_3 PF13415.1 KFM05261.1 - 1.1e-36 124.1 15.0 6.2e-06 26.2 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain BTB PF00651.26 KFM05261.1 - 1.1e-33 115.4 0.3 2.6e-33 114.3 0.2 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.10 KFM05261.1 - 6.6e-32 108.0 6.4 1e-06 28.2 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.1 KFM05261.1 - 2.8e-09 36.7 12.2 0.12 12.3 0.0 6.2 7 0 0 7 7 7 4 Kelch motif Varsurf_PPLC PF03490.8 KFM05261.1 - 0.095 12.3 0.0 3.3 7.4 0.0 2.6 2 0 0 2 2 2 0 Variant-surface-glycoprotein phospholipase C PQQ_3 PF13570.1 KFM05261.1 - 4.3 7.7 14.3 1.2 9.5 0.4 4.4 4 0 0 4 4 4 0 PQQ-like domain DUF3337 PF11816.3 KFM05262.1 - 6e-83 278.9 0.1 8.3e-83 278.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.27 KFM05262.1 - 6.1e-44 146.3 6.3 3.3e-08 33.1 0.0 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KFM05262.1 - 0.006 15.3 1.4 4.3 5.9 0.0 3.9 1 1 1 2 2 2 2 Nup133 N terminal like Nup160 PF11715.3 KFM05262.1 - 0.029 12.5 6.1 2.7 6.0 0.9 4.0 1 1 3 4 4 4 0 Nucleoporin Nup120/160 GRASP55_65 PF04495.9 KFM05263.1 - 4e-78 260.1 0.0 5.3e-61 204.6 0.0 2.3 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 KFM05263.1 - 4.4e-06 26.4 0.0 0.0029 17.4 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PAZ_siRNAbind PF12212.3 KFM05263.1 - 0.04 13.5 0.3 0.076 12.6 0.2 1.5 1 0 0 1 1 1 0 Piwi/Argonaute/Zwille siRNA-binding domain LIM PF00412.17 KFM05266.1 - 6.5e-09 35.7 11.3 7.2e-09 35.5 7.8 1.0 1 0 0 1 1 1 1 LIM domain Rieske PF00355.21 KFM05266.1 - 0.059 12.9 3.9 0.069 12.7 2.7 1.1 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain OTT_1508_deam PF14441.1 KFM05266.1 - 0.43 10.3 3.4 0.43 10.3 2.3 1.1 1 0 0 1 1 1 0 OTT_1508-like deaminase Dynactin_p62 PF05502.8 KFM05266.1 - 0.62 8.7 5.4 0.71 8.5 3.8 1.0 1 0 0 1 1 1 0 Dynactin p62 family Rad50_zn_hook PF04423.9 KFM05266.1 - 1.6 8.2 5.8 2.4 7.7 4.0 1.3 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-RING_2 PF13639.1 KFM05266.1 - 2.1 8.2 10.1 3.4 7.5 7.0 1.6 1 1 0 1 1 1 0 Ring finger domain Sugar_tr PF00083.19 KFM05267.1 - 1.2e-36 126.3 11.8 1.7e-36 125.7 8.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFM05267.1 - 7.2e-31 107.1 16.5 1.2e-30 106.4 11.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KFM05267.1 - 6.7e-07 28.0 6.5 2.3e-05 22.9 0.1 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 KFM05268.1 - 9e-30 103.6 20.5 4.3e-29 101.3 14.2 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFM05268.1 - 5e-28 97.8 22.2 5e-28 97.8 15.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KFM05268.1 - 0.00052 18.5 12.5 0.00097 17.6 1.8 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein E1-E2_ATPase PF00122.15 KFM05268.1 - 1.1 8.2 3.3 0.36 9.8 0.2 1.6 2 0 0 2 2 2 0 E1-E2 ATPase TIR PF01582.15 KFM05269.1 - 1.4e-19 69.9 0.2 1.8e-19 69.5 0.1 1.2 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.1 KFM05269.1 - 6.4e-13 48.7 0.0 8.4e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 TIR domain ETC_C1_NDUFA4 PF04800.7 KFM05269.1 - 0.039 13.8 0.0 0.071 12.9 0.0 1.4 1 0 0 1 1 1 0 ETC complex I subunit conserved region Pkinase PF00069.20 KFM05270.1 - 2.1e-61 207.3 0.0 2.7e-61 206.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM05270.1 - 4.9e-40 137.2 0.0 6.8e-40 136.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PB1 PF00564.19 KFM05270.1 - 2.8e-13 49.3 0.0 7.3e-13 47.9 0.0 1.8 1 0 0 1 1 1 1 PB1 domain Kinase-like PF14531.1 KFM05270.1 - 0.00041 19.4 0.0 0.0078 15.2 0.0 2.2 1 1 1 2 2 2 1 Kinase-like Thiolase_N PF00108.18 KFM05271.1 - 7.7e-81 270.9 1.6 1.3e-80 270.1 1.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KFM05271.1 - 4e-50 168.3 0.3 8.4e-50 167.3 0.2 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.5 KFM05271.1 - 0.00016 21.6 0.0 0.00049 20.0 0.0 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 KFM05271.1 - 0.00026 20.5 1.4 0.059 13.0 0.0 2.7 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 KFM05271.1 - 0.0013 18.2 0.8 0.004 16.6 0.1 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PapD-like PF14874.1 KFM05272.1 - 0.012 15.5 1.1 0.63 10.0 0.0 3.3 4 0 0 4 4 4 0 Flagellar-associated PapD-like MYCBPAP PF14646.1 KFM05272.1 - 0.12 11.1 0.3 1 8.0 0.0 2.5 3 0 0 3 3 3 0 MYCBP-associated protein family KR PF08659.5 KFM05272.1 - 0.25 11.0 0.0 0.41 10.2 0.0 1.2 1 0 0 1 1 1 0 KR domain PI-PLC-X PF00388.14 KFM05273.1 - 8.9e-68 226.2 0.1 2e-67 225.1 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KFM05273.1 - 1.1e-46 157.6 0.0 2.2e-46 156.6 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 KFM05273.1 - 1.3e-22 79.5 0.1 1.3e-22 79.5 0.1 2.4 3 0 0 3 3 3 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 KFM05273.1 - 3.9e-20 71.4 0.4 8.5e-20 70.4 0.3 1.6 1 0 0 1 1 1 1 C2 domain EF-hand_10 PF14788.1 KFM05273.1 - 7.9e-06 25.4 0.7 2e-05 24.1 0.5 1.8 1 0 0 1 1 1 1 EF hand Gelsolin PF00626.17 KFM05274.1 - 2.9e-98 321.6 0.0 1.5e-17 63.0 0.0 6.3 6 0 0 6 6 6 6 Gelsolin repeat NIF PF03031.13 KFM05275.1 - 6.8e-51 172.0 0.0 9.3e-51 171.6 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase tRNA-synt_2b PF00587.20 KFM05276.1 - 1.8e-71 239.2 0.0 3.4e-71 238.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KFM05276.1 - 1.8e-23 82.3 0.2 1.5e-22 79.2 0.0 2.4 2 1 0 2 2 2 1 Anticodon binding domain WHEP-TRS PF00458.15 KFM05276.1 - 1.6e-10 40.4 4.5 6.1e-10 38.6 3.1 2.0 1 0 0 1 1 1 1 WHEP-TRS domain OS-D PF03392.8 KFM05276.1 - 0.0048 16.8 0.6 0.016 15.1 0.1 2.1 2 0 0 2 2 2 1 Insect pheromone-binding family, A10/OS-D zf-H2C2_2 PF13465.1 KFM05278.1 - 2.8e-62 204.0 47.9 8.7e-10 38.4 0.5 8.8 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.21 KFM05278.1 - 1.4e-46 154.0 58.4 6.5e-07 29.3 0.5 8.8 8 1 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM05278.1 - 6.5e-30 101.2 43.3 2.7e-05 24.1 0.8 8.2 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM05278.1 - 5.2e-15 55.0 24.7 0.003 17.6 0.0 8.1 8 0 0 8 8 8 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFM05278.1 - 3.6e-12 45.7 45.2 0.044 13.6 0.5 8.9 8 1 0 8 8 8 5 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 KFM05278.1 - 8.1e-08 32.0 35.1 0.0015 18.4 1.6 7.3 4 2 3 7 7 7 3 Zinc ribbon domain zf-met PF12874.2 KFM05278.1 - 1.9e-05 24.6 33.9 0.28 11.4 0.1 8.0 8 0 0 8 8 8 2 Zinc-finger of C2H2 type Prok-RING_1 PF14446.1 KFM05278.1 - 2.1e-05 24.1 17.9 4.9 6.9 0.1 7.6 8 0 0 8 8 8 0 Prokaryotic RING finger family 1 XPA_N PF01286.13 KFM05278.1 - 0.00074 19.1 31.1 1.4 8.6 0.3 7.5 8 0 0 8 8 8 2 XPA protein N-terminal zf-LYAR PF08790.6 KFM05278.1 - 0.002 17.8 31.6 0.2 11.4 0.1 7.3 8 0 0 8 8 7 2 LYAR-type C2HC zinc finger C1_4 PF07975.7 KFM05278.1 - 0.008 16.1 26.8 0.62 10.1 0.7 5.7 1 1 4 6 6 6 2 TFIIH C1-like domain BolA PF01722.13 KFM05278.1 - 0.009 15.9 8.6 6.2 6.8 0.0 4.5 2 1 2 4 4 4 0 BolA-like protein DZR PF12773.2 KFM05278.1 - 0.017 14.9 26.6 6.9 6.5 5.5 4.9 2 2 0 2 2 2 0 Double zinc ribbon zf-RING_3 PF14369.1 KFM05278.1 - 0.023 14.7 23.4 0.94 9.5 0.1 6.8 7 0 0 7 7 7 0 zinc-finger Elf1 PF05129.8 KFM05278.1 - 0.023 14.3 0.8 0.023 14.3 0.6 4.5 1 1 3 5 5 5 0 Transcription elongation factor Elf1 like LIM PF00412.17 KFM05278.1 - 0.024 14.6 28.3 4.3 7.4 1.7 6.4 2 2 5 7 7 7 0 LIM domain DUF899 PF05988.7 KFM05278.1 - 0.041 13.3 6.6 0.8 9.0 0.1 4.0 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF899) zf-Di19 PF05605.7 KFM05278.1 - 0.093 12.8 30.9 0.072 13.2 2.0 6.6 2 1 5 7 7 7 0 Drought induced 19 protein (Di19), zinc-binding CpXC PF14353.1 KFM05278.1 - 0.11 12.5 21.1 0.41 10.5 0.6 6.3 3 3 2 5 5 4 0 CpXC protein Cren7 PF11520.3 KFM05278.1 - 0.13 11.9 0.3 2.9 7.6 0.0 3.2 4 0 0 4 4 3 0 Chromatin protein Cren7 TFIIS_C PF01096.13 KFM05278.1 - 0.18 11.4 30.9 2.8 7.6 0.1 7.7 8 0 0 8 8 8 0 Transcription factor S-II (TFIIS) TP1 PF02079.11 KFM05278.1 - 0.19 11.5 2.2 28 4.5 0.0 3.8 2 1 2 4 4 4 0 Nuclear transition protein 1 HypA PF01155.14 KFM05278.1 - 0.22 11.1 21.3 3.1 7.5 0.5 4.7 1 1 2 3 3 3 0 Hydrogenase expression/synthesis hypA family zf-trcl PF13451.1 KFM05278.1 - 0.24 11.0 31.3 1.4 8.6 2.4 7.3 7 1 0 7 7 7 0 Probable zinc-binding domain zf-AN1 PF01428.11 KFM05278.1 - 0.45 10.4 42.9 3.5 7.5 0.1 8.1 5 3 2 8 8 8 0 AN1-like Zinc finger zf-C2HC_2 PF13913.1 KFM05278.1 - 0.5 10.0 33.6 2.8 7.7 0.2 7.8 8 0 0 8 8 8 0 zinc-finger of a C2HC-type DNA_RNApol_7kD PF03604.8 KFM05278.1 - 0.53 9.8 29.2 14 5.2 0.1 7.5 7 1 0 7 7 7 0 DNA directed RNA polymerase, 7 kDa subunit zf-TRAF PF02176.13 KFM05278.1 - 0.61 10.4 30.6 0.12 12.7 1.4 5.5 1 1 6 7 7 7 0 TRAF-type zinc finger Yippee-Mis18 PF03226.9 KFM05278.1 - 0.98 9.5 18.6 0.063 13.3 0.9 4.7 2 1 1 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly YhfH PF14149.1 KFM05278.1 - 1.6 8.6 21.9 12 5.7 0.2 6.4 7 0 0 7 7 6 0 YhfH-like protein RRN7 PF11781.3 KFM05278.1 - 1.7 8.1 17.8 12 5.5 0.0 5.8 7 0 0 7 7 5 0 RNA polymerase I-specific transcription initiation factor Rrn7 zinc_ribbon_5 PF13719.1 KFM05278.1 - 1.8 8.1 28.3 3 7.5 0.1 7.0 7 1 0 7 7 6 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KFM05278.1 - 2.1 8.1 25.3 4.7 6.9 0.1 6.9 6 1 0 6 6 6 0 zinc-ribbon domain Evr1_Alr PF04777.8 KFM05278.1 - 2.6 8.0 22.6 18 5.2 0.1 6.2 1 1 6 7 7 7 0 Erv1 / Alr family FYDLN_acid PF09538.5 KFM05278.1 - 2.9 8.4 18.2 66 4.1 1.0 6.0 2 2 1 4 4 4 0 Protein of unknown function (FYDLN_acid) Ribosomal_L31 PF01197.13 KFM05278.1 - 6.5 6.8 7.5 41 4.2 1.8 4.3 2 1 1 3 3 2 0 Ribosomal protein L31 HNH PF01844.18 KFM05278.1 - 7 6.6 32.8 2 8.3 0.4 7.2 8 0 0 8 8 8 0 HNH endonuclease Ribosomal_L37ae PF01780.14 KFM05278.1 - 7.1 6.5 20.6 0.72 9.7 1.2 5.3 1 1 3 5 5 5 0 Ribosomal L37ae protein family zf-C2H2 PF00096.21 KFM05280.1 - 5.8e-61 199.2 107.6 9.8e-08 31.9 1.0 12.4 12 1 0 12 12 12 12 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM05280.1 - 7.6e-55 180.6 96.4 1.1e-09 38.1 0.7 13.1 13 0 0 13 13 13 12 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM05280.1 - 1.7e-33 112.4 92.9 9.7e-05 22.4 0.7 12.1 12 0 0 12 12 12 12 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM05280.1 - 4.3e-11 42.3 79.7 0.0054 16.5 0.1 13.1 13 0 0 13 13 13 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM05280.1 - 1.3e-10 41.1 33.5 0.24 11.6 0.0 10.6 10 0 0 10 10 10 4 Zinc-finger double-stranded RNA-binding LIM PF00412.17 KFM05280.1 - 0.024 14.7 60.2 0.025 14.6 0.3 9.3 3 2 7 10 10 9 0 LIM domain Zn-ribbon_8 PF09723.5 KFM05280.1 - 0.028 14.3 74.5 0.054 13.4 4.1 11.0 5 3 5 10 10 10 0 Zinc ribbon domain zf-met PF12874.2 KFM05280.1 - 0.077 13.2 50.9 0.88 9.8 0.2 9.8 9 1 1 10 10 10 0 Zinc-finger of C2H2 type Imm-NTF2-2 PF15631.1 KFM05280.1 - 0.11 12.4 0.0 5.4 7.0 0.0 3.4 3 2 2 5 5 5 0 NTF2 fold immunity protein BolA PF01722.13 KFM05280.1 - 0.16 11.9 17.9 6.7 6.7 0.1 6.4 4 1 3 7 7 7 0 BolA-like protein C1_4 PF07975.7 KFM05280.1 - 0.56 10.2 54.6 0.068 13.1 3.8 7.6 2 2 5 8 8 8 0 TFIIH C1-like domain Chordopox_RPO7 PF05864.7 KFM05280.1 - 1.4 9.0 0.0 1.4 9.0 0.0 6.4 8 2 2 10 10 9 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) GAGA PF09237.6 KFM05280.1 - 3.4 7.3 27.4 0.91 9.1 0.3 6.0 5 1 2 7 7 7 0 GAGA factor 7tm_2 PF00002.19 KFM05281.1 - 7.1e-79 264.3 23.2 8.7e-79 264.0 16.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 KFM05281.1 - 3.4e-20 71.8 1.9 7.4e-20 70.7 1.4 1.6 1 0 0 1 1 1 1 Hormone receptor domain DUF2976 PF11190.3 KFM05281.1 - 5.7 6.5 7.4 25 4.5 1.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) DUF4205 PF13898.1 KFM05283.1 - 1.2e-141 471.4 0.0 1.3e-141 471.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) MIP PF00230.15 KFM05284.1 - 2e-79 266.2 10.1 2.3e-79 266.0 7.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein 7tm_2 PF00002.19 KFM05285.1 - 2e-81 272.6 10.5 3e-81 272.1 7.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 KFM05285.1 - 2.3e-27 94.7 1.5 2.3e-27 94.7 1.0 2.2 2 0 0 2 2 2 1 Hormone receptor domain Na_Ca_ex PF01699.19 KFM05285.1 - 9.6 5.8 10.0 0.13 11.8 1.3 2.1 2 1 1 3 3 3 0 Sodium/calcium exchanger protein 7tm_2 PF00002.19 KFM05286.1 - 2.1e-77 259.5 18.0 2.6e-77 259.2 12.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 KFM05286.1 - 1.6e-20 72.8 2.4 1.6e-20 72.8 1.7 1.8 2 0 0 2 2 2 1 Hormone receptor domain 7tm_2 PF00002.19 KFM05287.1 - 6.2e-80 267.7 21.0 7.9e-80 267.4 14.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 KFM05287.1 - 5.5e-22 77.5 3.3 1.2e-21 76.5 2.3 1.6 1 0 0 1 1 1 1 Hormone receptor domain DUF843 PF05814.6 KFM05287.1 - 0.32 10.8 2.9 0.65 9.8 0.1 2.6 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) Longin PF13774.1 KFM05288.1 - 5.2e-15 54.7 0.0 8.8e-15 54.0 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain SCAMP PF04144.8 KFM05288.1 - 0.054 13.3 4.1 0.09 12.6 2.8 1.3 1 0 0 1 1 1 0 SCAMP family Pro_isomerase PF00160.16 KFM05289.1 - 1.2e-44 152.2 0.3 3.4e-44 150.7 0.2 1.9 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Kelch_1 PF01344.20 KFM05290.1 - 2.5e-35 119.7 0.1 1.1e-10 40.8 0.0 5.6 5 0 0 5 5 5 5 Kelch motif BTB PF00651.26 KFM05290.1 - 5.2e-35 119.7 1.8 8.6e-35 119.0 0.5 1.9 2 0 0 2 2 2 1 BTB/POZ domain Kelch_6 PF13964.1 KFM05290.1 - 4e-29 99.5 0.0 4.1e-07 29.8 0.0 5.4 2 1 3 5 5 5 4 Kelch motif BACK PF07707.10 KFM05290.1 - 9.8e-29 99.2 0.4 3.2e-28 97.5 0.1 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_4 PF13418.1 KFM05290.1 - 1.4e-20 72.7 0.1 6.6e-07 28.9 0.0 5.7 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.1 KFM05290.1 - 2.1e-19 69.1 0.1 6.4e-05 22.9 0.0 5.8 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.10 KFM05290.1 - 6.5e-15 54.2 0.9 0.0075 15.9 0.0 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.1 KFM05290.1 - 1.4e-14 53.6 0.9 0.0016 18.3 0.1 5.1 5 0 0 5 5 5 3 Kelch motif DUF3342 PF11822.3 KFM05290.1 - 0.0082 15.3 2.7 0.033 13.3 0.3 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF3342) MBOAT PF03062.14 KFM05291.1 - 3.3e-13 49.4 13.5 3.6e-13 49.3 8.8 1.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family LPP PF04728.8 KFM05292.1 - 0.017 14.8 4.3 1.4 8.8 0.0 4.4 5 0 0 5 5 5 0 Lipoprotein leucine-zipper TMF_DNA_bd PF12329.3 KFM05292.1 - 0.064 13.0 0.4 0.064 13.0 0.3 8.0 5 1 2 8 8 8 0 TATA element modulatory factor 1 DNA binding YgbB PF02542.11 KFM05292.1 - 0.071 12.9 0.2 0.071 12.9 0.2 2.3 3 0 0 3 3 3 0 YgbB family HIG_1_N PF04588.8 KFM05293.1 - 7.2e-23 80.0 0.5 1.2e-22 79.4 0.4 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF998 PF06197.8 KFM05293.1 - 0.021 14.1 0.2 0.025 13.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF998) Pkinase PF00069.20 KFM05294.1 - 7.4e-48 162.9 0.0 8.7e-48 162.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM05294.1 - 2.8e-29 101.9 0.0 3.7e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM05294.1 - 1.4e-06 27.4 0.0 3e-06 26.4 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KFM05294.1 - 0.015 15.0 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 KFM05294.1 - 0.017 14.1 0.2 0.028 13.5 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family I-set PF07679.11 KFM05295.1 - 4.4e-39 132.2 0.0 1.8e-18 66.1 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM05295.1 - 6.4e-22 77.4 0.0 3.4e-10 39.8 0.0 2.9 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.20 KFM05295.1 - 2.7e-15 56.2 0.0 6.9e-08 32.4 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 KFM05295.1 - 1.7e-12 47.6 1.4 0.00012 22.5 0.0 3.5 3 1 0 3 3 3 2 Immunoglobulin domain V-set PF07686.12 KFM05295.1 - 9.9e-09 35.1 0.1 0.015 15.2 0.0 3.7 1 1 1 2 2 2 2 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM05295.1 - 1.9e-08 34.0 0.0 0.0017 18.2 0.0 2.9 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain PH PF00169.24 KFM05295.1 - 8.5e-08 32.3 0.2 2.8e-07 30.6 0.1 2.0 2 0 0 2 2 2 1 PH domain RhoGEF PF00621.15 KFM05295.1 - 7.9e-05 22.6 0.2 0.00016 21.5 0.1 1.5 1 0 0 1 1 1 1 RhoGEF domain BiPBP_C PF06832.7 KFM05295.1 - 0.00035 20.4 0.0 0.57 10.1 0.0 2.8 2 0 0 2 2 2 2 Penicillin-Binding Protein C-terminus Family C1-set PF07654.10 KFM05295.1 - 0.023 14.6 0.3 0.84 9.6 0.0 3.1 3 0 0 3 3 3 0 Immunoglobulin C1-set domain DUF4608 PF15381.1 KFM05296.1 - 4e-24 84.5 4.3 4.6e-24 84.3 2.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4608) DUF4582 PF15189.1 KFM05297.1 - 1.4e-81 271.7 0.9 1.8e-81 271.4 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4582) ALIX_LYPXL_bnd PF13949.1 KFM05297.1 - 0.12 11.2 0.0 0.25 10.2 0.0 1.5 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV GCV_T_C PF08669.6 KFM05298.1 - 6.4e-07 29.3 0.0 1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain GCV_T PF01571.16 KFM05298.1 - 0.014 14.7 0.0 0.027 13.8 0.0 1.5 1 1 0 1 1 1 0 Aminomethyltransferase folate-binding domain Connexin PF00029.14 KFM05299.1 - 1e-51 173.5 0.3 2.4e-51 172.3 0.2 1.6 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 KFM05299.1 - 3.9e-31 106.6 10.8 9.8e-31 105.3 7.5 1.7 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain DUF1240 PF06836.7 KFM05299.1 - 0.044 13.9 0.1 0.83 9.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) Apc13p PF05839.6 KFM05299.1 - 0.14 12.1 1.6 0.36 10.8 1.1 1.6 1 0 0 1 1 1 0 Apc13p protein Guanylate_kin PF00625.16 KFM05300.1 - 4.9e-68 228.1 0.0 5.7e-68 227.9 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.1 KFM05300.1 - 2.2e-06 28.0 0.1 5.3e-06 26.7 0.0 1.7 1 1 1 2 2 1 1 AAA domain AAA_16 PF13191.1 KFM05300.1 - 4.3e-06 26.8 0.2 1e-05 25.5 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFM05300.1 - 5.2e-06 26.6 0.2 0.0001 22.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KFM05300.1 - 1e-05 26.3 0.2 4.4e-05 24.2 0.2 2.0 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KFM05300.1 - 3.4e-05 24.1 0.0 8.6e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_33 PF13671.1 KFM05300.1 - 5.6e-05 23.0 0.1 0.00021 21.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KFM05300.1 - 0.0001 21.4 0.1 0.00019 20.6 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KFM05300.1 - 0.00013 21.9 0.0 0.00024 21.0 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.1 KFM05300.1 - 0.00025 20.9 0.0 0.00053 19.8 0.0 1.8 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KFM05300.1 - 0.001 18.2 0.0 0.0028 16.7 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin Arch_ATPase PF01637.13 KFM05300.1 - 0.0017 18.1 0.6 0.0063 16.2 0.4 1.9 1 1 0 1 1 1 1 Archaeal ATPase AAA_29 PF13555.1 KFM05300.1 - 0.0025 17.3 0.1 0.0046 16.4 0.1 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 KFM05300.1 - 0.0025 17.2 0.2 0.021 14.2 0.0 1.9 2 0 0 2 2 2 1 AAA-like domain NACHT PF05729.7 KFM05300.1 - 0.0033 17.1 0.0 0.0074 15.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain cobW PF02492.14 KFM05300.1 - 0.0048 16.3 0.1 0.015 14.7 0.0 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 KFM05300.1 - 0.005 17.3 0.0 0.0087 16.5 0.0 1.6 1 1 0 1 1 1 1 Miro-like protein NTPase_1 PF03266.10 KFM05300.1 - 0.0071 16.0 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 NTPase KAP_NTPase PF07693.9 KFM05300.1 - 0.0079 15.2 0.0 0.013 14.5 0.0 1.6 1 1 0 1 1 1 1 KAP family P-loop domain RNA_helicase PF00910.17 KFM05300.1 - 0.01 16.0 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.4 KFM05300.1 - 0.012 14.6 0.1 0.34 9.8 0.0 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 KFM05300.1 - 0.013 15.6 0.4 0.033 14.3 0.0 1.9 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KFM05300.1 - 0.019 14.9 0.1 0.028 14.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KFM05300.1 - 0.02 14.6 0.2 0.27 10.9 0.0 2.6 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) UPF0079 PF02367.12 KFM05300.1 - 0.028 14.0 0.0 0.059 13.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 KFM05300.1 - 0.029 14.6 4.9 0.64 10.2 3.4 2.1 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 KFM05300.1 - 0.052 13.0 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 KFM05300.1 - 0.055 13.0 0.0 0.12 11.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KFM05300.1 - 0.058 13.1 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain NB-ARC PF00931.17 KFM05300.1 - 0.06 12.2 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_21 PF13304.1 KFM05300.1 - 0.065 13.1 1.7 0.32 10.9 1.2 1.9 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 KFM05300.1 - 0.076 12.8 0.2 0.16 11.8 0.1 1.7 1 1 0 2 2 2 0 Dynamin family SNARE PF05739.14 KFM05301.1 - 1.2e-08 34.5 7.0 1.7e-08 34.0 1.8 2.4 2 0 0 2 2 2 1 SNARE domain GRAM PF02893.15 KFM05301.1 - 0.018 14.5 0.0 0.04 13.4 0.0 1.6 1 0 0 1 1 1 0 GRAM domain V-SNARE_C PF12352.3 KFM05301.1 - 0.12 12.4 2.2 6.2 6.9 0.0 2.6 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Cupin_8 PF13621.1 KFM05302.1 - 2.4e-22 79.6 2.9 3.8e-22 78.9 2.0 1.3 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 KFM05302.1 - 8.2e-20 71.1 0.2 2.7e-19 69.5 0.1 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase MORN PF02493.15 KFM05303.1 - 2e-21 74.3 37.2 5.3e-07 28.9 3.0 8.9 8 1 0 8 8 8 7 MORN repeat VPS9 PF02204.13 KFM05303.1 - 2.2e-19 69.4 0.1 4.4e-19 68.4 0.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Carn_acyltransf PF00755.15 KFM05304.1 - 1e-210 700.8 0.0 1.2e-210 700.5 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase TCR PF03638.10 KFM05305.1 - 6e-17 61.2 52.2 1.5e-13 50.3 15.9 3.0 3 0 0 3 3 3 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain GMAP PF06540.6 KFM05306.1 - 1.3e-27 95.2 0.0 1.6e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 Galanin message associated peptide (GMAP) Galanin PF01296.13 KFM05306.1 - 3e-22 78.1 1.9 4.3e-22 77.6 1.3 1.3 1 0 0 1 1 1 1 Galanin SAPS PF04499.10 KFM05307.1 - 9.9e-107 357.5 12.2 6e-67 226.3 5.4 3.9 3 2 1 4 4 4 2 SIT4 phosphatase-associated protein FliC PF12445.3 KFM05307.1 - 0.016 15.3 3.2 0.048 13.7 2.2 1.8 1 0 0 1 1 1 0 Flagellin protein Atx10homo_assoc PF09759.4 KFM05307.1 - 0.065 12.9 1.9 0.31 10.7 0.1 2.9 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain Ldl_recept_b PF00058.12 KFM05308.1 - 3.1e-154 501.1 50.1 1.7e-13 50.6 0.0 20.5 20 0 0 20 20 20 20 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.1 KFM05308.1 - 8.1e-39 131.4 65.7 1.1e-12 47.7 5.5 5.6 5 0 0 5 5 5 4 Coagulation Factor Xa inhibitory site Ldl_recept_a PF00057.13 KFM05308.1 - 4.8e-32 109.5 58.1 5.3e-13 48.6 7.7 4.4 5 0 0 5 5 5 3 Low-density lipoprotein receptor domain class A SGL PF08450.7 KFM05308.1 - 1.6e-18 66.9 23.5 0.028 13.7 0.5 11.4 7 4 3 12 12 12 7 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 KFM05308.1 - 7.8e-09 35.4 0.0 9 6.3 0.0 8.3 8 1 1 9 9 9 1 Arylesterase NHL PF01436.16 KFM05308.1 - 6.4e-05 22.6 0.4 16 5.6 0.0 6.9 8 0 0 8 8 8 1 NHL repeat Methyltransf_12 PF08242.7 KFM05308.1 - 0.053 14.0 0.4 2.2e+02 2.4 0.0 5.6 5 2 1 6 6 6 0 Methyltransferase domain Lactonase PF10282.4 KFM05308.1 - 0.054 12.5 0.0 29 3.5 0.0 4.2 5 0 0 5 5 5 0 Lactonase, 7-bladed beta-propeller Toxin_3 PF00537.13 KFM05309.1 - 0.13 12.1 2.4 0.24 11.2 1.6 1.5 1 0 0 1 1 1 0 Scorpion toxin-like domain Choline_kinase PF01633.15 KFM05312.1 - 1.9e-77 259.6 0.1 2.6e-77 259.1 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 KFM05312.1 - 1.7e-11 44.3 0.0 2.2e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KFM05312.1 - 1.3e-07 31.0 0.2 7.1e-07 28.6 0.1 2.1 1 1 0 1 1 1 1 Ecdysteroid kinase Sec34 PF04136.10 KFM05312.1 - 0.078 12.6 0.3 5.8 6.5 0.1 2.3 2 0 0 2 2 2 0 Sec34-like family LRR_6 PF13516.1 KFM05313.1 - 8.2e-36 118.0 57.2 0.00027 20.6 0.2 14.2 14 0 0 14 14 14 11 Leucine Rich repeat LRR_4 PF12799.2 KFM05313.1 - 1.4e-21 75.6 34.8 0.00092 18.7 0.1 8.6 7 2 0 7 7 7 7 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 KFM05313.1 - 1e-11 42.9 39.5 1.4 9.4 0.0 13.4 14 0 0 14 14 14 5 Leucine rich repeat LRR_1 PF00560.28 KFM05313.1 - 5.2e-11 40.9 36.6 0.79 9.9 0.1 13.2 14 0 0 14 14 14 4 Leucine Rich Repeat LRR_8 PF13855.1 KFM05313.1 - 0.00016 21.3 37.7 0.03 14.0 1.2 8.3 4 3 6 10 10 9 7 Leucine rich repeat YusW PF14039.1 KFM05313.1 - 0.085 13.1 0.1 70 3.7 0.0 3.6 4 0 0 4 4 4 0 YusW-like protein Ras PF00071.17 KFM05314.1 - 1.8e-58 196.4 0.0 2.1e-58 196.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM05314.1 - 3.6e-20 72.6 0.0 4.9e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM05314.1 - 9.2e-10 38.0 0.0 1.1e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFM05314.1 - 1.8e-07 30.7 0.1 9.3e-07 28.4 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFM05314.1 - 1.1e-05 25.3 0.0 1.3e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFM05314.1 - 0.0021 17.2 0.0 0.0024 17.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 KFM05314.1 - 0.0032 16.7 0.0 0.026 13.8 0.0 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.1 KFM05314.1 - 0.021 14.9 0.1 0.43 10.7 0.1 2.5 1 1 1 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 KFM05314.1 - 0.029 13.9 0.3 0.74 9.3 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.1 KFM05314.1 - 0.034 13.5 0.3 0.073 12.4 0.2 1.8 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 KFM05314.1 - 0.04 12.9 0.0 0.072 12.1 0.0 1.6 1 1 0 1 1 1 0 Septin DUF258 PF03193.11 KFM05314.1 - 0.05 12.7 0.1 0.063 12.4 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 DUF2075 PF09848.4 KFM05314.1 - 0.071 12.0 0.1 1.4 7.7 0.0 1.9 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) G-alpha PF00503.15 KFM05314.1 - 0.12 10.9 0.0 4.2 5.9 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit CbiA PF01656.18 KFM05314.1 - 0.13 11.6 0.0 0.8 9.0 0.0 2.0 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_14 PF13173.1 KFM05314.1 - 0.14 12.0 0.1 0.21 11.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain ThiF PF00899.16 KFM05314.1 - 0.18 11.6 0.5 2.8 7.7 0.1 2.2 2 0 0 2 2 2 0 ThiF family AAA_17 PF13207.1 KFM05314.1 - 0.29 11.9 1.1 28 5.5 0.7 2.6 2 1 0 2 2 2 0 AAA domain LRR_4 PF12799.2 KFM05315.1 - 5.1e-19 67.4 8.8 1.7e-10 40.2 0.0 3.9 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM05315.1 - 6e-15 54.7 19.8 2.4e-07 30.3 0.7 3.6 2 1 3 5 5 5 4 Leucine rich repeat LRR_1 PF00560.28 KFM05315.1 - 1.2e-06 27.6 11.7 0.081 12.9 0.5 5.5 4 1 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.1 KFM05315.1 - 1.7e-05 24.4 18.7 0.088 12.9 0.1 6.2 5 2 2 7 7 7 2 Leucine Rich repeat LRR_7 PF13504.1 KFM05315.1 - 8.2e-05 22.1 13.4 2.1 8.9 0.0 5.9 7 0 0 7 7 7 2 Leucine rich repeat LRR_9 PF14580.1 KFM05315.1 - 0.0013 18.3 2.5 0.013 15.0 1.0 2.4 1 1 2 3 3 3 3 Leucine-rich repeat RA PF00788.18 KFM05317.1 - 2.7e-10 40.5 0.5 6.8e-10 39.3 0.0 1.9 2 0 0 2 2 1 1 Ras association (RalGDS/AF-6) domain MsyB PF13984.1 KFM05317.1 - 0.058 13.4 0.2 0.058 13.4 0.1 1.7 2 0 0 2 2 2 0 MsyB protein AAA_13 PF13166.1 KFM05317.1 - 0.19 10.1 12.4 0.26 9.7 8.6 1.2 1 0 0 1 1 1 0 AAA domain Reo_sigmaC PF04582.7 KFM05317.1 - 0.2 10.8 0.9 0.7 9.0 0.4 1.8 2 0 0 2 2 2 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 KFM05317.1 - 0.48 10.7 4.4 2.3 8.5 1.0 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein V_ATPase_I PF01496.14 KFM05317.1 - 0.66 7.7 16.1 1.6 6.5 11.1 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Lectin_N PF03954.9 KFM05317.1 - 0.67 9.3 5.7 0.98 8.8 2.2 2.5 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain ATG16 PF08614.6 KFM05317.1 - 0.87 9.3 28.6 0.33 10.7 6.2 3.1 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) SlyX PF04102.7 KFM05317.1 - 1.2 9.5 17.0 1.3 9.4 4.1 4.3 4 1 0 4 4 4 0 SlyX Sipho_Gp157 PF05565.6 KFM05317.1 - 2.4 7.7 9.4 1.2 8.6 4.3 2.0 1 1 1 2 2 2 0 Siphovirus Gp157 CDC37_N PF03234.9 KFM05317.1 - 2.7 8.2 11.8 6.2 7.1 8.2 1.6 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding DUF3416 PF11896.3 KFM05317.1 - 3 7.7 8.8 0.18 11.7 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3416) HR1 PF02185.11 KFM05317.1 - 4 7.2 15.0 1.7 8.4 5.2 2.9 2 1 0 2 2 2 0 Hr1 repeat DUF4140 PF13600.1 KFM05317.1 - 4.3 7.8 14.2 4.5 7.7 1.5 3.2 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) FUSC PF04632.7 KFM05317.1 - 5.8 5.2 7.6 8.1 4.7 5.2 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Sec20 PF03908.8 KFM05317.1 - 9.1 6.0 6.8 0.82 9.4 0.8 2.2 3 0 0 3 3 3 0 Sec20 PHD PF00628.24 KFM05318.1 - 8.5e-14 50.9 3.7 1.9e-13 49.8 2.5 1.7 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 KFM05318.1 - 0.0011 18.6 1.5 0.0029 17.2 1.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 C1_1 PF00130.17 KFM05318.1 - 0.013 15.1 0.1 0.04 13.6 0.0 1.8 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 KFM05318.1 - 0.017 14.3 0.5 0.036 13.3 0.3 1.6 1 0 0 1 1 1 0 PHD-finger IRF-3 PF10401.4 KFM05320.1 - 4.3e-48 163.2 0.9 7.8e-48 162.4 0.3 1.7 2 0 0 2 2 2 1 Interferon-regulatory factor 3 IRF PF00605.12 KFM05320.1 - 2.1e-13 50.0 0.0 3.8e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor Mito_carr PF00153.22 KFM05321.1 - 6.8e-66 218.0 1.8 1.1e-23 82.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein NYAP_C PF15452.1 KFM05321.1 - 0.019 13.9 0.6 2.7 6.8 0.1 2.6 3 0 0 3 3 3 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter LRR_4 PF12799.2 KFM05322.1 - 2.9e-24 84.2 30.2 2.5e-06 26.9 1.9 6.9 3 1 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM05322.1 - 3e-20 71.7 37.8 3.2e-09 36.3 4.1 5.3 2 1 2 5 5 5 4 Leucine rich repeat LRR_1 PF00560.28 KFM05322.1 - 3.8e-12 44.4 35.8 0.0068 16.2 0.4 9.6 10 0 0 10 10 10 6 Leucine Rich Repeat Death PF00531.17 KFM05322.1 - 1.9e-10 40.3 0.2 5e-10 39.0 0.1 1.8 1 0 0 1 1 1 1 Death domain ZU5 PF00791.15 KFM05322.1 - 6.6e-09 35.3 0.2 4.3e-07 29.5 0.0 2.4 2 0 0 2 2 2 1 ZU5 domain Peptidase_S68 PF10461.4 KFM05322.1 - 1e-08 34.7 7.6 3.4e-08 33.0 1.6 2.7 2 0 0 2 2 2 1 Peptidase S68 LRR_7 PF13504.1 KFM05322.1 - 4.2e-07 29.0 34.4 1.4 9.4 0.5 10.1 9 0 0 9 9 9 4 Leucine rich repeat Ribosomal_60s PF00428.14 KFM05323.1 - 4e-27 94.4 8.8 5.1e-27 94.0 6.1 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein TFIID_30kDa PF03540.8 KFM05323.1 - 0.064 13.0 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit EF-hand_7 PF13499.1 KFM05324.1 - 6.4e-07 29.4 0.2 2.5e-05 24.3 0.1 3.6 3 2 1 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.1 KFM05324.1 - 1.2e-06 27.9 0.2 0.004 16.9 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 KFM05324.1 - 4.9e-06 25.4 1.0 0.033 13.5 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 KFM05324.1 - 0.055 13.0 0.1 0.25 10.9 0.1 2.3 1 0 0 1 1 1 0 EF-hand domain pair Peptidase_S46 PF10459.4 KFM05324.1 - 1.8 6.8 14.2 2.6 6.3 9.8 1.4 1 0 0 1 1 1 0 Peptidase S46 Ras PF00071.17 KFM05325.1 - 1.4e-51 174.0 0.1 1.6e-51 173.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM05325.1 - 2.5e-21 76.3 0.0 3.3e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM05325.1 - 5e-15 55.1 0.0 5.9e-15 54.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFM05325.1 - 9.9e-10 37.9 0.0 1.1e-09 37.7 0.0 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFM05325.1 - 1e-09 38.1 0.0 3e-09 36.5 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFM05325.1 - 7.6e-08 32.3 0.0 9.3e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KFM05325.1 - 0.0019 17.4 0.2 0.0029 16.8 0.2 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KFM05325.1 - 0.0073 16.1 0.1 2.6 7.8 0.0 2.2 2 0 0 2 2 2 2 Dynamin family SRPRB PF09439.5 KFM05325.1 - 0.029 13.6 0.0 0.032 13.4 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_33 PF13671.1 KFM05325.1 - 0.029 14.2 0.0 0.052 13.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KFM05325.1 - 0.037 14.1 0.0 0.13 12.3 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.1 KFM05325.1 - 0.08 12.4 0.0 0.27 10.7 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.13 KFM05325.1 - 0.094 11.9 0.1 0.58 9.4 0.1 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B Septin PF00735.13 KFM05325.1 - 0.12 11.4 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Septin MobB PF03205.9 KFM05325.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Tetraspannin PF00335.15 KFM05326.1 - 5.5e-59 199.1 15.4 6.3e-59 198.9 10.7 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF4199 PF13858.1 KFM05326.1 - 0.0016 18.4 2.1 0.0016 18.4 1.4 1.8 2 1 0 2 2 1 1 Protein of unknown function (DUF4199) CD20 PF04103.10 KFM05326.1 - 0.0047 16.8 5.5 0.0047 16.8 3.8 2.3 2 1 0 2 2 2 1 CD20-like family DUF2215 PF10225.4 KFM05326.1 - 0.0063 16.0 0.5 0.012 15.0 0.1 1.8 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2215) Baculo_11_kDa PF06143.6 KFM05326.1 - 0.023 14.0 6.4 5.5 6.4 0.3 3.3 3 0 0 3 3 3 0 Baculovirus 11 kDa family DUF308 PF03729.8 KFM05326.1 - 0.032 14.2 5.5 0.032 14.2 3.8 2.6 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) Bap31 PF05529.7 KFM05326.1 - 0.043 13.2 0.1 0.067 12.6 0.1 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like MARVEL PF01284.18 KFM05326.1 - 0.086 12.6 9.8 0.11 12.3 0.6 2.4 1 1 1 2 2 2 0 Membrane-associating domain COX15-CtaA PF02628.10 KFM05326.1 - 0.091 11.6 4.4 0.19 10.5 3.0 1.5 1 1 0 1 1 1 0 Cytochrome oxidase assembly protein DUF4500 PF14937.1 KFM05326.1 - 0.11 12.3 1.8 8 6.3 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4500) DUF4064 PF13273.1 KFM05326.1 - 0.17 12.0 8.8 6.1 7.0 0.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) zf-DHHC PF01529.15 KFM05326.1 - 0.52 9.6 8.7 0.14 11.5 0.3 2.4 1 1 2 3 3 3 0 DHHC palmitoyltransferase Claudin_2 PF13903.1 KFM05326.1 - 0.66 9.6 12.0 1.3 8.6 6.5 2.5 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF4405 PF14358.1 KFM05326.1 - 2.4 8.3 8.0 12 6.0 1.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4405) ATP_synt_H PF05493.8 KFM05326.1 - 3.4 7.8 8.3 1.3 9.1 1.9 2.7 1 1 1 2 2 2 0 ATP synthase subunit H DUF3592 PF12158.3 KFM05326.1 - 4 7.2 9.7 4.1 7.2 3.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3592) Yip1 PF04893.12 KFM05326.1 - 4.8 6.6 12.7 17 4.8 8.9 1.6 1 1 0 1 1 1 0 Yip1 domain RNA_pol_N PF01194.12 KFM05327.1 - 1.7e-30 104.7 0.3 1.9e-30 104.6 0.2 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 KFM05327.1 - 0.096 12.7 0.3 0.16 12.0 0.2 1.4 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Tetraspannin PF00335.15 KFM05330.1 - 2.7e-43 147.7 16.9 3e-43 147.6 11.7 1.0 1 0 0 1 1 1 1 Tetraspanin family CD20 PF04103.10 KFM05330.1 - 9.7e-05 22.3 4.2 0.00014 21.8 2.9 1.4 1 0 0 1 1 1 1 CD20-like family GP38 PF05268.6 KFM05330.1 - 0.052 12.9 0.0 0.079 12.3 0.0 1.2 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 Claudin_2 PF13903.1 KFM05330.1 - 0.33 10.6 10.5 0.022 14.4 2.9 2.0 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF2207 PF09972.4 KFM05330.1 - 0.67 8.4 4.6 0.91 8.0 3.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Glyco_hydro_18 PF00704.23 KFM05331.1 - 1e-22 81.0 0.0 1.3e-22 80.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.8 KFM05331.1 - 0.096 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 Adaptin_N PF01602.15 KFM05332.1 - 5.3e-142 473.8 2.8 6.8e-142 473.4 1.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 KFM05332.1 - 1.6e-44 150.4 0.0 4.5e-44 149.0 0.0 1.9 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 KFM05332.1 - 7.2e-24 84.3 0.5 1.4e-23 83.4 0.3 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.2 KFM05332.1 - 8e-07 29.0 0.3 0.00041 20.2 0.0 2.8 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KFM05332.1 - 1.2e-05 25.5 3.4 0.0088 16.3 0.1 4.7 3 1 1 4 4 4 1 HEAT repeats HEAT PF02985.17 KFM05332.1 - 0.0012 18.7 2.5 14 6.1 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat RIX1 PF08167.7 KFM05332.1 - 0.0083 15.8 0.2 0.49 10.0 0.0 3.1 2 1 0 3 3 3 1 rRNA processing/ribosome biogenesis M11L PF11099.3 KFM05332.1 - 0.027 14.2 1.8 1 9.0 0.0 2.9 3 0 0 3 3 3 0 Apoptosis regulator M11L like TIP120 PF08623.5 KFM05332.1 - 0.068 12.7 0.6 12 5.4 0.1 2.5 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) Myelin-PO_C PF10570.4 KFM05332.1 - 0.17 11.9 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 Myelin-PO cytoplasmic C-term p65 binding region Yae1_N PF09811.4 KFM05333.1 - 6.1e-16 57.6 42.3 4.2e+03 -2.7 29.3 4.4 1 1 0 1 1 1 0 Essential protein Yae1, N terminal SR-25 PF10500.4 KFM05334.1 - 0.005 16.3 4.8 0.0063 16.0 3.3 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Muted PF14942.1 KFM05334.1 - 0.011 15.5 3.0 0.016 15.0 2.1 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Alpha-2-MRAP_C PF06401.6 KFM05334.1 - 0.018 14.9 1.9 0.025 14.4 1.3 1.1 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain RP-C_C PF11800.3 KFM05334.1 - 0.02 14.5 2.2 0.026 14.2 1.6 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Fmp27_WPPW PF10359.4 KFM05334.1 - 0.05 12.0 1.6 0.057 11.8 1.1 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4407 PF14362.1 KFM05334.1 - 0.06 12.2 2.6 0.071 12.0 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) XhlA PF10779.4 KFM05334.1 - 0.062 13.2 7.0 0.1 12.5 4.9 1.4 1 0 0 1 1 1 0 Haemolysin XhlA MCLC PF05934.6 KFM05334.1 - 0.14 10.4 2.0 0.19 10.0 1.4 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) BUD22 PF09073.5 KFM05334.1 - 0.14 11.2 10.9 0.17 10.9 7.5 1.1 1 0 0 1 1 1 0 BUD22 Mnd1 PF03962.10 KFM05334.1 - 0.43 10.2 7.1 0.6 9.7 4.9 1.1 1 0 0 1 1 1 0 Mnd1 family APG6 PF04111.7 KFM05334.1 - 0.72 8.8 6.4 0.9 8.5 4.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4611 PF15387.1 KFM05334.1 - 5.7 7.1 15.4 0.095 12.8 4.5 2.1 1 1 1 2 2 1 0 Domain of unknown function (DUF4611) AA_permease_2 PF13520.1 KFM05337.1 - 1.4e-55 188.5 42.9 1.6e-55 188.3 29.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFM05337.1 - 4.3e-24 84.7 38.0 5.5e-24 84.3 26.3 1.1 1 0 0 1 1 1 1 Amino acid permease LRR_4 PF12799.2 KFM05338.1 - 2.5e-18 65.2 16.7 1.6e-09 37.1 1.9 4.0 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM05338.1 - 1.4e-09 37.5 23.1 1.2e-06 28.1 3.6 3.2 2 1 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.1 KFM05338.1 - 7.8e-05 22.3 19.4 0.0032 17.3 0.1 5.3 3 1 2 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.28 KFM05338.1 - 0.0046 16.7 23.6 0.19 11.9 0.4 5.4 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 KFM05338.1 - 0.027 14.6 15.2 3.1 8.4 0.1 5.4 5 0 0 5 5 5 0 Leucine rich repeat E2F_TDP PF02319.15 KFM05339.1 - 1e-14 53.8 0.2 1.9e-14 52.9 0.2 1.5 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Carb_anhydrase PF00194.16 KFM05340.1 - 7.3e-110 365.9 0.0 8e-110 365.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.16 KFM05341.1 - 6.1e-109 362.9 0.0 6.8e-109 362.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.16 KFM05342.1 - 4.1e-105 350.3 0.0 4.6e-105 350.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.16 KFM05343.1 - 3.6e-119 396.4 0.0 4e-119 396.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase HECT PF00632.20 KFM05344.1 - 6.2e-95 317.9 0.5 9.9e-95 317.3 0.4 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 KFM05344.1 - 1.9e-47 158.6 33.1 4.9e-13 48.6 2.2 4.5 4 0 0 4 4 4 4 WW domain C2 PF00168.25 KFM05344.1 - 1.3e-08 34.5 0.1 3e-08 33.3 0.1 1.6 1 0 0 1 1 1 1 C2 domain TPR_17 PF13431.1 KFM05345.1 - 4.2e-08 32.7 1.3 0.15 12.3 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 KFM05345.1 - 1.5e-07 30.7 12.9 0.14 11.8 0.0 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.1 KFM05345.1 - 4.8e-07 30.0 3.1 0.052 13.8 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFM05345.1 - 5.6e-06 26.8 4.9 1.3 9.7 0.5 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFM05345.1 - 1.7e-05 24.3 9.0 0.14 11.8 0.0 4.3 2 2 2 4 4 4 4 TPR repeat TPR_2 PF07719.12 KFM05345.1 - 3.9e-05 23.2 15.9 0.7 9.9 0.0 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFM05345.1 - 0.00021 21.6 2.7 50 4.9 0.0 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 KFM05345.1 - 0.011 15.6 4.4 1.3 9.0 0.2 3.6 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFM05345.1 - 0.072 12.9 9.7 1 9.3 0.1 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat Peptidase_M10 PF00413.19 KFM05346.1 - 7.4e-59 197.8 0.0 1.2e-58 197.2 0.0 1.3 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.14 KFM05346.1 - 1.3e-55 184.9 16.4 1.2e-16 60.1 0.4 4.6 4 0 0 4 4 4 4 Hemopexin DUF3377 PF11857.3 KFM05346.1 - 9.3e-38 127.7 0.2 1.6e-37 126.9 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) PG_binding_1 PF01471.13 KFM05346.1 - 1.8e-10 40.5 0.1 1.1e-09 38.0 0.0 2.2 2 0 0 2 2 2 1 Putative peptidoglycan binding domain Astacin PF01400.19 KFM05346.1 - 7.6e-05 22.1 0.9 0.21 10.9 0.0 2.2 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Peptidase_M54 PF07998.6 KFM05346.1 - 0.04 13.6 0.0 0.087 12.5 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M54 Metallopep PF12044.3 KFM05346.1 - 0.08 11.3 0.0 0.12 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_2 PF13574.1 KFM05346.1 - 0.12 12.4 0.2 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KFM05346.1 - 0.18 12.3 0.5 0.36 11.3 0.3 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFM05346.1 - 0.2 11.1 0.1 0.36 10.3 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KFM05346.1 - 0.24 11.3 0.3 0.57 10.0 0.1 1.6 2 0 0 2 2 2 0 Metallo-peptidase family M12 DNA_ligase_A_M PF01068.16 KFM05348.1 - 1.3e-52 178.1 0.2 2.3e-52 177.3 0.2 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KFM05348.1 - 4.7e-44 150.3 0.0 9.2e-44 149.3 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_IV PF11411.3 KFM05348.1 - 9.1e-21 73.3 2.1 2e-20 72.2 1.5 1.6 1 0 0 1 1 1 1 DNA ligase IV DNA_ligase_A_C PF04679.10 KFM05348.1 - 8.3e-16 58.1 0.0 4e-15 55.9 0.0 2.2 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 KFM05348.1 - 2.9e-15 56.1 0.2 6.7e-10 38.9 0.0 3.3 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain mRNA_cap_enzyme PF01331.14 KFM05348.1 - 0.0012 18.6 1.3 0.0086 15.7 0.9 2.2 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain DUF1395 PF07160.7 KFM05348.1 - 0.1 12.0 1.8 0.19 11.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1395) Abhydrolase_5 PF12695.2 KFM05349.1 - 8.1e-23 80.7 0.0 1.1e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFM05349.1 - 2e-14 54.0 0.0 1.5e-13 51.2 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFM05349.1 - 3.8e-11 42.9 0.0 3e-08 33.5 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.7 KFM05349.1 - 1.2e-08 33.8 0.0 7.9e-05 21.3 0.0 3.1 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 KFM05349.1 - 3.4e-06 26.6 0.0 0.0023 17.3 0.0 2.8 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 KFM05349.1 - 7.7e-05 22.3 0.0 9.6e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFM05349.1 - 0.00044 19.5 0.0 0.00061 19.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.6 KFM05349.1 - 0.00088 19.0 0.0 0.0067 16.1 0.0 2.0 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.13 KFM05349.1 - 0.0011 18.4 0.0 0.019 14.4 0.0 2.0 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.8 KFM05349.1 - 0.0037 16.7 0.0 0.0051 16.2 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.3 KFM05349.1 - 0.0063 16.3 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Esterase PF00756.15 KFM05349.1 - 0.034 13.5 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF1057 PF06342.7 KFM05349.1 - 0.044 12.5 0.0 0.064 12.0 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Lipase_3 PF01764.20 KFM05349.1 - 0.097 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DLH PF01738.13 KFM05349.1 - 0.17 11.1 0.0 0.81 8.9 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family TNF PF00229.13 KFM05350.1 - 3.4e-17 62.2 0.0 5.4e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family Collagen PF01391.13 KFM05351.1 - 2.6e-201 651.4 766.8 5.3e-10 38.7 17.4 27.8 5 4 18 23 23 23 22 Collagen triple helix repeat (20 copies) C4 PF01413.14 KFM05351.1 - 1.6e-94 311.5 3.8 2.1e-49 166.1 0.4 2.2 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen Collagen PF01391.13 KFM05352.1 - 8.6e-27 92.4 83.7 7.3e-09 35.0 13.5 4.1 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) C4 PF01413.14 KFM05353.1 - 1.3e-91 302.1 2.7 2.1e-47 159.7 0.2 2.0 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen COMP PF11598.3 KFM05353.1 - 0.11 12.6 2.0 1.3 9.1 0.2 2.2 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein LpxD PF04613.9 KFM05353.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD Ras PF00071.17 KFM05354.1 - 4.7e-14 52.1 0.0 1.4e-13 50.5 0.0 1.7 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KFM05354.1 - 0.011 16.2 0.0 0.02 15.3 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein Arf PF00025.16 KFM05354.1 - 0.016 14.4 0.0 0.02 14.1 0.0 1.3 1 1 0 1 1 1 0 ADP-ribosylation factor family Carb_kinase PF01256.12 KFM05355.1 - 4e-55 186.7 0.0 4.7e-55 186.5 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.10 KFM05355.1 - 0.018 14.1 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family Suc_Fer-like PF06999.7 KFM05355.1 - 0.064 13.2 0.0 0.097 12.6 0.0 1.2 1 0 0 1 1 1 0 Sucrase/ferredoxin-like tRNA-synt_1e PF01406.14 KFM05356.1 - 3.4e-98 328.4 0.2 4.4e-98 328.1 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 KFM05356.1 - 2.8e-09 36.1 1.3 5.3e-05 22.0 0.2 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KFM05356.1 - 0.00049 18.2 0.0 0.00065 17.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.6 KFM05356.1 - 0.00059 20.0 0.0 0.0016 18.6 0.0 1.8 1 0 0 1 1 1 1 DALR domain tRNA-synt_1f PF01921.13 KFM05356.1 - 0.024 13.3 0.6 0.057 12.0 0.2 1.7 1 1 1 2 2 2 0 tRNA synthetases class I (K) ING PF12998.2 KFM05357.1 - 2.1e-33 114.7 5.8 2.1e-33 114.7 4.0 2.3 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 KFM05357.1 - 1.6e-10 40.4 8.7 3.8e-10 39.2 6.1 1.7 1 0 0 1 1 1 1 PHD-finger DUF4661 PF15576.1 KFM05357.1 - 0.02 14.5 3.9 0.029 14.0 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) PHD_2 PF13831.1 KFM05357.1 - 0.028 13.7 3.8 0.052 12.8 2.6 1.4 1 0 0 1 1 1 0 PHD-finger SRP-alpha_N PF04086.8 KFM05357.1 - 0.029 13.7 15.6 0.05 12.9 10.8 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal FadA PF09403.5 KFM05357.1 - 0.058 13.3 0.7 0.058 13.3 0.5 2.9 1 1 0 2 2 1 0 Adhesion protein FadA ApoB100_C PF12491.3 KFM05357.1 - 0.068 12.8 0.6 0.13 11.9 0.4 1.4 1 0 0 1 1 1 0 Apolipoprotein B100 C terminal zf-HC5HC2H PF13771.1 KFM05357.1 - 0.11 12.6 2.6 0.42 10.7 1.7 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain Hid1 PF12722.2 KFM05357.1 - 0.56 7.8 11.4 0.7 7.5 7.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein zf-RING-like PF08746.6 KFM05357.1 - 0.93 9.5 6.7 2.1 8.4 4.6 1.7 1 0 0 1 1 1 0 RING-like domain DDHD PF02862.12 KFM05357.1 - 1.8 8.2 7.5 3 7.5 5.2 1.5 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.7 KFM05357.1 - 4.2 7.1 12.5 6.4 6.5 8.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ank_2 PF12796.2 KFM05358.1 - 1.1e-26 92.9 0.4 2.9e-17 62.7 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFM05358.1 - 4.3e-19 67.2 2.3 1.3e-06 27.9 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 KFM05358.1 - 7.6e-17 60.9 1.1 1.4e-08 34.7 0.1 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFM05358.1 - 2.1e-16 59.8 0.2 8.4e-08 32.5 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM05358.1 - 3.4e-11 42.2 0.1 6.4e-05 22.8 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat RVT_1 PF00078.22 KFM05359.1 - 0.0055 16.0 0.0 0.0088 15.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RhoGEF PF00621.15 KFM05360.1 - 3e-32 111.9 1.3 3e-32 111.9 0.9 2.9 3 0 0 3 3 3 1 RhoGEF domain SH3_2 PF07653.12 KFM05360.1 - 2.4e-18 65.3 0.3 6e-18 64.0 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KFM05360.1 - 2e-17 62.4 0.1 4.1e-17 61.4 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM05360.1 - 7.4e-17 60.4 0.1 1.4e-16 59.6 0.1 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 KFM05360.1 - 1.4e-09 38.1 0.2 3.9e-09 36.6 0.0 1.9 2 0 0 2 2 2 1 PH domain GlutR_dimer PF00745.15 KFM05360.1 - 0.075 12.9 4.1 0.23 11.4 2.9 1.8 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain Spc97_Spc98 PF04130.8 KFM05361.1 - 5.5e-127 424.3 7.2 8e-127 423.8 5.0 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family E1-E2_ATPase PF00122.15 KFM05363.1 - 1e-18 67.2 0.7 6.1e-18 64.6 0.0 2.5 3 0 0 3 3 3 1 E1-E2 ATPase HAD PF12710.2 KFM05363.1 - 2.6e-18 66.8 0.0 9.7e-18 65.0 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFM05363.1 - 3.9e-14 53.5 2.7 1.5e-10 41.9 0.7 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFM05363.1 - 1.3e-11 44.2 0.2 9e-11 41.5 0.0 2.3 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFM05363.1 - 0.00059 19.4 0.1 0.097 12.2 0.0 2.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KFM05363.1 - 0.11 12.7 0.2 0.42 10.8 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase RhoGEF PF00621.15 KFM05364.1 - 3.2e-39 134.6 5.3 3.2e-39 134.6 3.7 3.3 2 1 0 3 3 3 1 RhoGEF domain CRAL_TRIO_2 PF13716.1 KFM05364.1 - 2e-14 53.7 0.0 5.7e-14 52.2 0.0 1.9 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Spectrin PF00435.16 KFM05364.1 - 1.8e-07 31.3 16.5 0.0004 20.6 0.0 4.7 3 2 1 4 4 4 2 Spectrin repeat Trypsin PF00089.21 KFM05365.1 - 5.5e-63 212.4 0.6 6.2e-63 212.3 0.4 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 KFM05365.1 - 7.8e-06 25.3 0.0 1.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 KFM05365.1 - 0.00039 20.3 0.1 0.00066 19.6 0.1 1.3 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 KFM05366.1 - 7.3e-66 221.8 0.1 8.1e-66 221.7 0.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 KFM05366.1 - 6.7e-06 26.0 0.0 9.9e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.6 KFM05366.1 - 0.00067 19.0 0.0 0.00099 18.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) PTS_EIIA_2 PF00359.17 KFM05366.1 - 0.11 12.1 0.1 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Trypsin PF00089.21 KFM05367.1 - 1.6e-35 122.6 0.0 1.7e-35 122.5 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 KFM05367.1 - 0.0075 15.5 0.0 0.0099 15.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Cullin PF00888.17 KFM05368.1 - 6.6e-175 583.0 21.6 9.7e-175 582.4 15.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KFM05368.1 - 1.4e-26 92.0 0.2 5.2e-26 90.2 0.1 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain Membr_traf_MHD PF10540.4 KFM05368.1 - 0.0068 16.2 1.2 0.61 9.8 0.0 3.6 3 0 0 3 3 3 1 Munc13 (mammalian uncoordinated) homology domain HTH_34 PF13601.1 KFM05368.1 - 0.022 14.7 0.0 0.94 9.5 0.0 2.7 2 0 0 2 2 2 0 Winged helix DNA-binding domain TrmB PF01978.14 KFM05368.1 - 0.084 12.5 0.0 14 5.4 0.0 2.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Lamp PF01299.12 KFM05369.1 - 4.4e-117 390.6 7.2 4.6e-112 374.1 4.1 2.0 1 1 1 2 2 2 2 Lysosome-associated membrane glycoprotein (Lamp) RabGAP-TBC PF00566.13 KFM05370.1 - 1.4e-55 188.0 0.1 2.1e-55 187.5 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ADP_ribosyl_GH PF03747.9 KFM05372.1 - 2.7e-41 142.2 0.0 3.2e-41 142.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Cullin_binding PF03556.10 KFM05373.1 - 2.1e-40 137.5 0.7 2.1e-40 137.5 0.5 2.2 2 1 0 2 2 2 1 Cullin binding UBA_4 PF14555.1 KFM05373.1 - 1.9e-09 36.8 1.7 5.4e-09 35.4 0.0 2.6 3 0 0 3 3 3 1 UBA-like domain PV_NSP1 PF12433.3 KFM05373.1 - 0.25 11.4 2.7 0.56 10.3 1.4 1.9 2 0 0 2 2 2 0 Parvovirus non-structural protein 1 Na_H_Exchanger PF00999.16 KFM05374.1 - 1.8e-73 247.3 42.8 2.3e-73 246.9 29.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF16 PF01519.11 KFM05374.1 - 1.8 8.8 6.1 2.8 8.1 3.8 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 Fib_alpha PF08702.5 KFM05374.1 - 7.8 6.6 7.5 3.6 7.7 2.8 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DP PF08781.5 KFM05375.1 - 8.2e-58 194.1 2.2 8.2e-58 194.1 1.5 1.7 2 1 1 3 3 3 1 Transcription factor DP E2F_TDP PF02319.15 KFM05375.1 - 3.8e-27 93.6 0.3 9.5e-27 92.3 0.2 1.7 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Na_K-ATPase PF00287.13 KFM05377.1 - 1.5e-102 342.3 0.9 1.7e-102 342.1 0.6 1.0 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain FAM70 PF14967.1 KFM05378.1 - 7.5e-177 587.3 7.8 8.3e-177 587.2 5.4 1.0 1 0 0 1 1 1 1 FAM70 protein DUF4064 PF13273.1 KFM05378.1 - 0.0036 17.3 10.5 0.52 10.4 5.1 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF4064) DUF1097 PF06496.6 KFM05378.1 - 0.35 10.6 11.3 2 8.2 4.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1097) DUF2407_C PF13373.1 KFM05378.1 - 0.54 10.1 2.3 8.6 6.2 0.7 2.4 2 0 0 2 2 2 0 DUF2407 C-terminal domain DUF2371 PF10177.4 KFM05378.1 - 2.4 8.0 4.2 36 4.2 0.2 3.0 2 1 1 3 3 3 0 Uncharacterised conserved protein (DUF2371) Laminin_G_1 PF00054.18 KFM05379.1 - 6.5e-30 103.8 0.0 5.5e-21 74.9 0.0 2.3 2 0 0 2 2 2 2 Laminin G domain Laminin_G_2 PF02210.19 KFM05379.1 - 7.7e-29 100.3 0.0 1.1e-13 51.2 0.0 2.3 2 0 0 2 2 2 2 Laminin G domain EGF_CA PF07645.10 KFM05379.1 - 1.3e-21 76.3 53.5 8.5e-08 32.0 5.0 5.0 4 0 0 4 4 4 4 Calcium-binding EGF domain Gla PF00594.15 KFM05379.1 - 8.4e-15 54.1 8.3 1.9e-14 53.0 5.7 1.7 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain cEGF PF12662.2 KFM05379.1 - 3.3e-13 49.0 32.3 2e-07 30.4 2.9 5.1 4 0 0 4 4 4 3 Complement Clr-like EGF-like FXa_inhibition PF14670.1 KFM05379.1 - 3.5e-12 46.2 60.7 3.3e-07 30.3 7.8 4.6 4 0 0 4 4 4 3 Coagulation Factor Xa inhibitory site EGF PF00008.22 KFM05379.1 - 1.2e-09 37.8 46.6 0.00036 20.4 4.1 4.8 4 0 0 4 4 4 4 EGF-like domain EGF_3 PF12947.2 KFM05379.1 - 0.0006 19.7 47.0 0.021 14.7 3.5 4.7 4 0 0 4 4 4 3 EGF domain PT PF04886.7 KFM05381.1 - 3.8e-09 35.7 0.0 0.056 12.7 0.0 4.5 1 1 0 1 1 1 1 PT repeat Yae1_N PF09811.4 KFM05382.1 - 1e-19 69.7 61.7 1.5e+04 -22.3 42.8 5.5 1 1 0 1 1 1 0 Essential protein Yae1, N terminal RasGAP PF00616.14 KFM05383.1 - 2.5e-46 157.8 0.3 4.3e-46 157.0 0.2 1.4 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 KFM05383.1 - 1.4e-34 117.7 0.0 2.7e-17 62.3 0.0 2.8 2 0 0 2 2 2 2 C2 domain BTK PF00779.14 KFM05383.1 - 3.8e-14 52.0 5.6 7.4e-14 51.0 3.9 1.5 1 0 0 1 1 1 1 BTK motif PH PF00169.24 KFM05383.1 - 3.3e-10 40.0 0.3 3.3e-10 40.0 0.2 2.0 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 KFM05383.1 - 0.011 15.9 0.1 0.047 13.8 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain PH_8 PF15409.1 KFM05383.1 - 0.014 15.4 0.1 0.045 13.8 0.1 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain Mcp5_PH PF12814.2 KFM05383.1 - 0.018 14.9 0.2 0.045 13.6 0.1 1.7 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology PH_7 PF15408.1 KFM05383.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain TPR_2 PF07719.12 KFM05384.1 - 1.7e-25 86.8 15.3 6.5e-06 25.6 0.1 9.6 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_11 PF13414.1 KFM05384.1 - 9.8e-24 82.7 19.3 6.4e-14 51.3 0.1 7.2 6 2 0 8 8 8 4 TPR repeat TPR_1 PF00515.23 KFM05384.1 - 1.8e-22 77.9 16.8 3.9e-08 32.5 0.1 8.2 9 0 0 9 9 9 4 Tetratricopeptide repeat Apc3 PF12895.2 KFM05384.1 - 9.8e-22 76.8 6.4 2.9e-12 46.5 5.3 4.8 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KFM05384.1 - 2e-21 75.7 1.0 4.5e-12 45.7 0.3 6.6 3 2 4 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFM05384.1 - 9.2e-17 59.5 2.2 0.01 15.5 0.0 6.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 KFM05384.1 - 2.5e-13 50.2 9.7 0.00022 21.7 0.0 5.4 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFM05384.1 - 9.6e-13 46.9 7.8 1.7e-05 24.2 0.1 5.2 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFM05384.1 - 5.8e-12 45.7 1.3 0.011 16.1 0.0 5.2 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFM05384.1 - 1.4e-11 43.6 1.8 0.023 14.8 0.0 5.8 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 KFM05384.1 - 3.6e-11 42.6 0.4 0.00014 21.7 0.2 5.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFM05384.1 - 1.7e-10 40.5 5.3 1 10.1 0.0 7.4 6 2 2 8 8 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 KFM05384.1 - 3.1e-05 23.7 4.2 0.007 16.1 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_3 PF07720.7 KFM05384.1 - 0.0049 16.6 1.7 5.6 6.8 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFM05384.1 - 0.14 12.6 15.9 2.9 8.5 0.2 6.9 9 0 0 9 9 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KFM05384.1 - 0.56 10.1 9.5 0.92 9.4 0.2 4.2 4 1 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Smg4_UPF3 PF03467.10 KFM05385.1 - 1.3e-55 188.0 0.1 1.3e-55 188.0 0.0 2.3 2 1 1 3 3 3 1 Smg-4/UPF3 family zf-H2C2_2 PF13465.1 KFM05386.1 - 0.00089 19.4 0.6 0.00089 19.4 0.4 5.7 5 0 0 5 5 5 1 Zinc-finger double domain zf-C2H2 PF00096.21 KFM05386.1 - 0.0095 16.2 0.1 0.0095 16.2 0.1 5.2 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 KFM05386.1 - 0.018 15.2 0.1 0.018 15.2 0.1 5.4 5 1 0 5 5 5 0 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 KFM05386.1 - 0.17 12.2 0.0 0.17 12.2 0.0 5.4 5 0 0 5 5 5 0 C2H2-type zinc finger Septin PF00735.13 KFM05387.1 - 2.6e-96 321.9 0.7 2.6e-96 321.9 0.5 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KFM05387.1 - 3.1e-05 23.8 0.6 6.4e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KFM05387.1 - 0.00024 21.1 0.0 0.00054 20.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFM05387.1 - 0.00027 21.0 0.1 0.0026 17.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KFM05387.1 - 0.0013 19.1 0.9 0.014 15.8 0.0 2.8 2 1 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 KFM05387.1 - 0.0015 17.9 0.2 1.5 8.2 0.0 2.8 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 KFM05387.1 - 0.0022 17.5 0.2 0.005 16.3 0.1 1.6 1 1 0 1 1 1 1 AAA-like domain T2SE PF00437.15 KFM05387.1 - 0.0026 16.6 0.0 0.0062 15.4 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein RHD3 PF05879.7 KFM05387.1 - 0.0028 15.6 0.4 0.0028 15.6 0.2 2.5 3 0 0 3 3 3 1 Root hair defective 3 GTP-binding protein (RHD3) AAA_29 PF13555.1 KFM05387.1 - 0.0039 16.7 0.1 0.0084 15.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KFM05387.1 - 0.011 16.0 0.3 0.035 14.4 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AIG1 PF04548.11 KFM05387.1 - 0.016 14.3 2.2 0.027 13.5 0.0 2.2 2 0 0 2 2 2 0 AIG1 family Dynamin_N PF00350.18 KFM05387.1 - 0.016 14.9 0.1 0.016 14.9 0.0 2.4 2 1 0 2 2 2 0 Dynamin family cobW PF02492.14 KFM05387.1 - 0.018 14.4 0.1 1.8 7.9 0.0 2.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 KFM05387.1 - 0.023 13.8 0.3 0.059 12.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 KFM05387.1 - 0.024 14.4 0.1 0.087 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 KFM05387.1 - 0.025 14.2 0.0 0.085 12.5 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_21 PF13304.1 KFM05387.1 - 0.026 14.4 0.9 0.052 13.5 0.6 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KFM05387.1 - 0.034 13.6 2.9 0.058 12.8 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family DltD_C PF04914.7 KFM05387.1 - 0.05 13.4 1.8 0.17 11.7 0.1 2.4 2 0 0 2 2 2 0 DltD C-terminal region IIGP PF05049.8 KFM05387.1 - 0.071 11.9 6.3 0.15 10.8 0.0 2.8 2 1 1 3 3 3 0 Interferon-inducible GTPase (IIGP) G-alpha PF00503.15 KFM05387.1 - 0.12 11.0 7.3 0.13 10.9 0.1 2.8 2 1 1 3 3 3 0 G-protein alpha subunit DUF87 PF01935.12 KFM05387.1 - 0.29 10.8 0.0 0.29 10.8 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF87 DUF763 PF05559.6 KFM05387.1 - 0.45 9.4 4.4 0.76 8.6 2.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF763) OmpH PF03938.9 KFM05387.1 - 2.7 7.9 14.2 5.5 6.9 9.8 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) AAA_18 PF13238.1 KFM05387.1 - 4.5 7.6 7.0 0.58 10.4 0.1 2.9 3 2 0 3 3 3 0 AAA domain SH3_9 PF14604.1 KFM05388.1 - 2.6e-42 142.1 1.2 1e-16 60.2 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.23 KFM05388.1 - 3.4e-35 119.1 0.5 3.5e-12 45.5 0.0 3.3 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.12 KFM05388.1 - 1.1e-24 85.6 0.4 8.5e-09 34.7 0.1 3.4 3 0 0 3 3 3 3 Variant SH3 domain PAT1 PF09770.4 KFM05388.1 - 1.2 7.3 7.3 1.7 6.7 5.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Death PF00531.17 KFM05390.1 - 6.9e-05 22.5 0.0 0.00019 21.1 0.0 1.7 1 1 0 1 1 1 1 Death domain DUF4199 PF13858.1 KFM05390.1 - 0.016 15.0 0.1 0.027 14.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF1510 PF07423.6 KFM05390.1 - 0.02 14.2 2.5 0.031 13.6 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TNFR_c6 PF00020.13 KFM05390.1 - 0.025 14.6 16.0 0.053 13.5 5.7 3.7 2 1 1 3 3 3 0 TNFR/NGFR cysteine-rich region SID-1_RNA_chan PF13965.1 KFM05390.1 - 0.06 11.4 0.4 0.089 10.9 0.3 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PIG-P PF08510.7 KFM05390.1 - 0.17 11.4 3.0 0.25 10.9 1.2 1.9 2 1 0 2 2 2 0 PIG-P DUF912 PF06024.7 KFM05390.1 - 0.46 10.5 5.6 0.2 11.7 0.4 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) FPL PF09758.4 KFM05391.1 - 0.012 15.3 1.0 0.021 14.5 0.7 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein NPV_P10 PF05531.7 KFM05392.1 - 0.00042 20.5 5.3 0.012 15.8 2.7 2.8 1 1 0 1 1 1 1 Nucleopolyhedrovirus P10 protein bZIP_1 PF00170.16 KFM05392.1 - 0.00047 20.0 4.7 0.00047 20.0 3.2 3.0 3 0 0 3 3 2 1 bZIP transcription factor HALZ PF02183.13 KFM05392.1 - 0.0013 18.3 2.1 0.0013 18.3 1.4 3.0 3 1 0 3 3 3 1 Homeobox associated leucine zipper BRO1 PF03097.13 KFM05392.1 - 0.0022 16.8 4.4 0.0025 16.6 3.0 1.2 1 0 0 1 1 1 1 BRO1-like domain Spc42p PF11544.3 KFM05392.1 - 0.012 15.4 7.4 0.012 15.4 5.2 2.9 2 1 0 2 2 2 0 Spindle pole body component Spc42p Atg14 PF10186.4 KFM05392.1 - 0.027 13.3 18.9 0.037 12.9 13.1 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF342 PF03961.8 KFM05392.1 - 0.093 11.1 11.0 0.12 10.7 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF3450 PF11932.3 KFM05392.1 - 0.18 11.0 16.5 0.0098 15.1 7.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Ferritin-like PF12902.2 KFM05392.1 - 0.27 10.8 6.8 0.21 11.1 0.9 2.2 1 1 1 2 2 2 0 Ferritin-like Rootletin PF15035.1 KFM05392.1 - 0.27 11.1 19.9 0.59 10.0 13.7 1.6 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Baculo_PEP_C PF04513.7 KFM05392.1 - 0.34 10.7 4.1 0.71 9.7 2.5 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF87 PF01935.12 KFM05392.1 - 0.44 10.3 7.7 0.31 10.8 4.0 1.6 1 1 0 1 1 1 0 Domain of unknown function DUF87 DUF2400 PF09674.5 KFM05392.1 - 0.49 10.0 6.9 0.51 10.0 1.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Tnp_P_element PF12017.3 KFM05392.1 - 0.52 9.5 5.3 0.62 9.2 2.9 1.7 1 1 1 2 2 2 0 Transposase protein CENP-F_leu_zip PF10473.4 KFM05392.1 - 0.53 10.1 25.2 0.46 10.3 8.6 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Syntaxin PF00804.20 KFM05392.1 - 0.55 10.4 14.2 0.18 12.0 7.3 2.0 1 1 0 1 1 1 0 Syntaxin UPF0242 PF06785.6 KFM05392.1 - 0.82 8.2 12.7 1 7.9 8.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) TMPIT PF07851.8 KFM05392.1 - 0.96 8.4 18.9 0.027 13.5 5.1 2.1 1 1 1 2 2 2 0 TMPIT-like protein FUSC PF04632.7 KFM05392.1 - 0.96 7.7 3.1 1.2 7.4 2.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Scaffolding_pro PF11418.3 KFM05392.1 - 1 9.7 8.7 1.3 9.4 4.8 2.3 1 1 0 2 2 1 0 Phi29 scaffolding protein TMF_TATA_bd PF12325.3 KFM05392.1 - 1.1 9.0 17.4 0.16 11.6 8.6 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4600 PF15372.1 KFM05392.1 - 1.1 9.4 16.5 0.2 11.8 5.2 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) SPX PF03105.14 KFM05392.1 - 1.2 8.9 7.6 1.4 8.6 5.3 1.2 1 0 0 1 1 1 0 SPX domain ING PF12998.2 KFM05392.1 - 1.2 9.4 15.7 0.061 13.6 4.2 2.7 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding MitMem_reg PF13012.1 KFM05392.1 - 1.4 8.9 8.4 0.19 11.8 2.8 1.9 2 0 0 2 2 1 0 Maintenance of mitochondrial structure and function Vps51 PF08700.6 KFM05392.1 - 1.8 8.4 8.7 1.5 8.7 4.0 2.5 1 1 0 2 2 2 0 Vps51/Vps67 Phage_GPO PF05929.6 KFM05392.1 - 1.9 7.6 8.1 2.6 7.2 5.6 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Syntaxin-6_N PF09177.6 KFM05392.1 - 2.9 8.3 9.2 8.8 6.8 6.2 2.1 1 1 0 1 1 1 0 Syntaxin 6, N-terminal PilJ PF13675.1 KFM05392.1 - 2.9 8.2 7.0 0.57 10.5 1.9 1.9 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF1664 PF07889.7 KFM05392.1 - 3.3 7.5 9.9 1.5 8.6 4.3 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF948 PF06103.6 KFM05392.1 - 3.7 7.4 7.5 3.2 7.6 1.5 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Utp12 PF04003.7 KFM05392.1 - 4.6 7.1 7.8 19 5.2 2.3 3.4 1 1 2 3 3 3 0 Dip2/Utp12 Family APG6 PF04111.7 KFM05392.1 - 5.3 5.9 22.4 1.6 7.7 13.3 1.6 1 1 1 2 2 2 0 Autophagy protein Apg6 Sec20 PF03908.8 KFM05392.1 - 6.5 6.5 11.0 0.75 9.5 1.9 2.9 1 1 1 3 3 3 0 Sec20 IncA PF04156.9 KFM05392.1 - 7.6 6.0 28.6 0.13 11.8 9.9 2.4 1 1 2 3 3 3 0 IncA protein Pro_isomerase PF00160.16 KFM05393.1 - 2.9e-39 134.7 1.0 3.2e-39 134.6 0.7 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ran_BP1 PF00638.13 KFM05394.1 - 1.5e-56 189.6 0.6 1.8e-56 189.4 0.4 1.0 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 KFM05394.1 - 7.5e-05 22.4 0.1 0.00012 21.7 0.0 1.3 1 1 0 1 1 1 1 WH1 domain TPR_2 PF07719.12 KFM05395.1 - 7e-09 34.9 0.1 1.1e-05 24.9 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFM05395.1 - 5.8e-08 32.0 0.1 2.9e-05 23.4 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFM05395.1 - 3.2e-07 30.3 0.0 0.024 15.2 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFM05395.1 - 1.2e-06 28.0 0.9 0.00011 21.8 0.1 2.4 2 1 0 2 2 2 1 TPR repeat TPR_17 PF13431.1 KFM05395.1 - 5.9e-05 22.9 0.1 0.66 10.3 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFM05395.1 - 0.00012 21.5 0.0 0.0016 18.0 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFM05395.1 - 0.0016 18.0 0.1 0.082 12.7 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFM05395.1 - 0.0077 16.5 0.2 2.5 8.4 0.0 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFM05395.1 - 0.015 15.1 0.1 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Sel1 PF08238.7 KFM05395.1 - 0.049 14.2 0.0 19 6.0 0.0 2.6 2 0 0 2 2 2 0 Sel1 repeat LIM PF00412.17 KFM05396.1 - 3e-62 206.5 62.6 2.8e-14 52.9 2.1 5.1 5 0 0 5 5 5 5 LIM domain DUF4428 PF14471.1 KFM05396.1 - 0.018 14.7 3.6 0.018 14.7 2.5 6.2 6 1 0 6 6 6 0 Domain of unknown function (DUF4428) GRIP PF01465.15 KFM05397.1 - 1.6e-16 59.5 0.3 5.4e-16 57.8 0.2 2.0 1 0 0 1 1 1 1 GRIP domain Sulfotransfer_1 PF00685.22 KFM05398.1 - 1e-92 310.2 3.5 1.2e-92 309.9 2.4 1.0 1 0 0 1 1 1 1 Sulfotransferase domain DUF2344 PF10105.4 KFM05399.1 - 0.095 12.1 0.4 0.16 11.4 0.1 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2344) SSF PF00474.12 KFM05400.1 - 3e-33 115.0 28.9 4.4e-33 114.5 20.0 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Glyco_transf_29 PF00777.13 KFM05402.1 - 2.2e-69 233.5 0.0 1.1e-68 231.2 0.0 1.8 1 1 1 2 2 2 1 Glycosyltransferase family 29 (sialyltransferase) 7tm_1 PF00001.16 KFM05403.1 - 2.3e-30 105.5 12.8 2.6e-30 105.4 8.9 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 KFM05403.1 - 1.1e-05 24.6 7.1 1.5e-05 24.3 4.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv TAS2R PF05296.8 KFM05403.1 - 0.00014 20.9 1.8 0.00016 20.6 1.2 1.1 1 0 0 1 1 1 1 Mammalian taste receptor protein (TAS2R) BCD PF15461.1 KFM05403.1 - 0.00058 19.3 6.8 0.0017 17.8 4.7 1.7 1 1 0 1 1 1 1 Beta-carotene 15,15'-dioxygenase Anoctamin PF04547.7 KFM05403.1 - 0.023 13.3 3.2 0.033 12.8 2.2 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel DUF2975 PF11188.3 KFM05403.1 - 0.044 13.4 3.9 0.063 13.0 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) DUF420 PF04238.7 KFM05403.1 - 0.72 9.8 7.3 0.37 10.7 2.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF420) PufQ PF05398.6 KFM05403.1 - 2 8.5 4.4 1.7 8.7 0.2 2.4 1 1 1 2 2 2 0 PufQ cytochrome subunit zf-LITAF-like PF10601.4 KFM05403.1 - 2.4 8.0 9.9 7.7 6.4 0.2 2.7 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain DUF1201 PF06716.6 KFM05403.1 - 6.8 6.5 12.3 0.55 10.1 4.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1201) Epimerase PF01370.16 KFM05406.1 - 3.8e-47 160.7 0.0 6.4e-47 159.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family UXS1_N PF11803.3 KFM05406.1 - 5.8e-22 77.2 0.0 1.3e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 UDP-glucuronate decarboxylase N-terminal RmlD_sub_bind PF04321.12 KFM05406.1 - 1.8e-12 46.7 0.0 2.4e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KFM05406.1 - 7.6e-12 44.6 0.4 1.7e-07 30.4 0.0 2.8 2 1 1 3 3 3 2 Male sterility protein Polysacc_synt_2 PF02719.10 KFM05406.1 - 1.3e-08 34.1 0.2 0.00016 20.6 0.0 2.9 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KFM05406.1 - 1.7e-08 33.5 0.0 6.4e-08 31.6 0.0 1.8 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KFM05406.1 - 0.00016 21.6 0.0 0.00023 21.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KFM05406.1 - 0.078 12.8 0.0 0.27 11.1 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase Augurin PF15187.1 KFM05407.1 - 1e-48 163.9 1.4 1.1e-48 163.7 1.0 1.0 1 0 0 1 1 1 1 Oesophageal cancer-related gene 4 SH3_9 PF14604.1 KFM05408.1 - 1.6e-42 142.8 6.4 2.4e-15 55.8 0.1 3.9 4 0 0 4 4 4 3 Variant SH3 domain SH3_1 PF00018.23 KFM05408.1 - 1.5e-41 139.4 12.3 5.5e-14 51.2 0.1 4.7 6 0 0 6 6 6 3 SH3 domain SH3_2 PF07653.12 KFM05408.1 - 3.7e-30 103.1 7.6 5.6e-10 38.5 0.1 4.3 4 1 1 5 5 5 3 Variant SH3 domain SH2 PF00017.19 KFM05408.1 - 4.7e-22 77.5 0.1 9.7e-22 76.5 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SH3_3 PF08239.6 KFM05408.1 - 4.9e-11 42.6 10.0 0.0011 19.1 0.2 3.6 3 1 0 3 3 3 3 Bacterial SH3 domain hSH3 PF14603.1 KFM05408.1 - 0.047 13.7 0.1 1.9 8.5 0.0 2.5 2 0 0 2 2 2 0 Helically-extended SH3 domain LIM PF00412.17 KFM05409.1 - 1e-46 156.8 70.9 4.4e-13 49.0 5.2 5.1 5 0 0 5 5 5 5 LIM domain Ureidogly_hydro PF04115.7 KFM05409.1 - 0.04 13.2 0.0 0.29 10.4 0.0 2.2 1 1 1 2 2 2 0 Ureidoglycolate hydrolase Ashwin PF15323.1 KFM05410.1 - 4.3e-71 239.3 12.1 4.8e-71 239.1 8.4 1.0 1 0 0 1 1 1 1 Developmental protein Vps39_2 PF10367.4 KFM05411.1 - 4.1e-29 100.9 0.1 9.3e-29 99.7 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 KFM05411.1 - 5.7e-26 90.6 5.6 2.4e-25 88.6 0.9 2.8 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.17 KFM05411.1 - 5.1e-14 52.3 0.1 1.5e-13 50.7 0.0 1.8 1 1 1 2 2 2 1 CNH domain Clathrin PF00637.15 KFM05411.1 - 5.2e-14 52.0 15.5 1.6e-08 34.2 4.6 2.5 2 0 0 2 2 2 2 Region in Clathrin and VPS TPR_2 PF07719.12 KFM05411.1 - 0.27 11.2 4.6 3.1 7.9 0.3 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFM05411.1 - 2.4 7.9 5.9 40 4.0 0.3 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_S9 PF00380.14 KFM05412.1 - 1.3e-33 115.7 0.1 2.5e-33 114.9 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 BCL_N PF04714.8 KFM05416.1 - 0.071 12.6 0.2 0.084 12.4 0.1 1.2 1 0 0 1 1 1 0 BCL7, N-terminal conserver region Claudin_2 PF13903.1 KFM05418.1 - 1.6e-37 128.8 8.4 2.2e-37 128.4 5.8 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 KFM05418.1 - 2.2e-06 27.4 10.1 0.00094 18.8 4.5 2.2 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family DUF2207 PF09972.4 KFM05418.1 - 0.36 9.3 7.3 0.25 9.8 3.8 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) L_HGMIC_fpl PF10242.4 KFM05418.1 - 2.1 8.2 11.2 8.3 6.3 7.8 2.1 1 1 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein MFS_1 PF07690.11 KFM05419.1 - 1.2e-36 126.2 23.0 1.5e-36 125.8 15.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFM05419.1 - 4.3e-08 32.1 2.0 4.3e-08 32.1 1.4 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter Na_H_Exchanger PF00999.16 KFM05420.1 - 7.8e-86 287.9 40.8 9e-86 287.7 28.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Na_H_Exchanger PF00999.16 KFM05421.1 - 1.8e-79 267.0 34.9 2.2e-79 266.7 24.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TIR PF01582.15 KFM05422.1 - 2.7e-33 114.3 0.1 8.4e-33 112.7 0.0 1.9 2 0 0 2 2 2 1 TIR domain Ig_2 PF13895.1 KFM05422.1 - 1.2e-13 51.0 1.4 0.0001 22.3 0.2 3.4 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.11 KFM05422.1 - 6.4e-11 41.9 2.0 0.0027 17.5 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.20 KFM05422.1 - 8.3e-06 25.8 0.4 0.54 10.4 0.1 3.8 4 0 0 4 4 4 3 Immunoglobulin domain TIR_2 PF13676.1 KFM05422.1 - 3.1e-05 24.0 0.0 7.9e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 TIR domain Ig_3 PF13927.1 KFM05422.1 - 0.00014 22.3 0.2 0.16 12.4 0.0 3.9 3 1 0 3 3 3 1 Immunoglobulin domain C1-set PF07654.10 KFM05422.1 - 0.002 18.1 0.1 1.5 8.8 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin C1-set domain TIR PF01582.15 KFM05423.1 - 1.3e-33 115.4 0.1 2.7e-33 114.3 0.0 1.6 1 0 0 1 1 1 1 TIR domain Ig_2 PF13895.1 KFM05423.1 - 2e-10 40.6 6.4 1.3e-06 28.4 0.4 3.6 3 0 0 3 3 3 2 Immunoglobulin domain Ig_3 PF13927.1 KFM05423.1 - 3.3e-08 33.8 7.0 0.00011 22.5 0.3 3.7 3 1 0 3 3 3 2 Immunoglobulin domain ig PF00047.20 KFM05423.1 - 1.9e-05 24.6 8.3 0.0064 16.5 0.1 3.6 4 1 0 4 4 4 2 Immunoglobulin domain V-set PF07686.12 KFM05423.1 - 0.00047 20.0 9.2 1 9.2 0.8 4.7 3 2 0 3 3 3 2 Immunoglobulin V-set domain TIR_2 PF13676.1 KFM05423.1 - 0.00083 19.4 0.0 0.0024 17.9 0.0 1.8 1 0 0 1 1 1 1 TIR domain I-set PF07679.11 KFM05423.1 - 0.0076 16.0 9.7 0.24 11.2 0.2 4.0 4 1 0 4 4 4 2 Immunoglobulin I-set domain DUF4342 PF14242.1 KFM05423.1 - 0.013 15.2 1.0 0.034 13.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) KSHV_K1 PF11049.3 KFM05423.1 - 0.027 14.4 1.2 0.26 11.3 0.0 2.9 3 0 0 3 3 3 0 Glycoprotein K1 of Kaposi's sarcoma-associated herpes virus TIR PF01582.15 KFM05424.1 - 2.4e-32 111.3 0.2 4e-32 110.5 0.1 1.4 1 0 0 1 1 1 1 TIR domain Ig_2 PF13895.1 KFM05424.1 - 4.3e-18 65.2 3.6 1.8e-06 27.9 0.0 3.6 4 0 0 4 4 3 3 Immunoglobulin domain Ig_3 PF13927.1 KFM05424.1 - 1.6e-14 54.0 0.3 0.002 18.5 0.0 3.8 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.11 KFM05424.1 - 1.9e-13 50.0 7.4 9.1e-07 28.6 0.0 3.6 4 0 0 4 4 3 3 Immunoglobulin I-set domain V-set PF07686.12 KFM05424.1 - 1.5e-09 37.7 8.4 0.0007 19.4 0.1 4.0 4 1 0 4 4 4 3 Immunoglobulin V-set domain ig PF00047.20 KFM05424.1 - 3.3e-08 33.5 11.1 0.0013 18.8 0.1 4.3 4 1 0 4 4 4 2 Immunoglobulin domain V-set_CD47 PF08204.6 KFM05424.1 - 6.7e-05 22.6 1.1 0.02 14.6 0.0 3.1 3 0 0 3 3 3 1 CD47 immunoglobulin-like domain C2-set_2 PF08205.7 KFM05424.1 - 0.0028 17.5 0.1 2.8 7.9 0.0 3.4 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain TIR_2 PF13676.1 KFM05424.1 - 0.0034 17.4 0.0 0.0063 16.6 0.0 1.4 1 0 0 1 1 1 1 TIR domain C2-set PF05790.10 KFM05424.1 - 0.021 14.7 0.0 1.1 9.2 0.0 3.1 3 0 0 3 3 3 0 Immunoglobulin C2-set domain BiPBP_C PF06832.7 KFM05424.1 - 0.026 14.4 0.0 0.088 12.7 0.0 1.9 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family TIR PF01582.15 KFM05425.1 - 2.9e-31 107.7 0.0 5.5e-31 106.8 0.0 1.5 1 0 0 1 1 1 1 TIR domain Ig_2 PF13895.1 KFM05425.1 - 7.5e-19 67.6 2.3 2e-06 27.8 0.1 3.5 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.11 KFM05425.1 - 1.7e-17 63.0 0.3 1.4e-05 24.8 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.1 KFM05425.1 - 7.9e-11 42.3 4.7 0.004 17.6 0.1 3.8 3 1 0 3 3 3 3 Immunoglobulin domain ig PF00047.20 KFM05425.1 - 6.1e-09 35.8 1.4 0.032 14.3 0.0 3.9 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.12 KFM05425.1 - 7.9e-07 28.9 6.6 0.003 17.4 0.8 4.7 3 1 1 4 4 4 2 Immunoglobulin V-set domain Lep_receptor_Ig PF06328.6 KFM05425.1 - 0.0035 17.1 1.5 0.04 13.7 0.1 2.9 3 0 0 3 3 3 1 Ig-like C2-type domain C2-set_2 PF08205.7 KFM05425.1 - 0.033 14.0 0.0 0.54 10.2 0.0 2.6 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain TIR PF01582.15 KFM05426.1 - 2.7e-37 127.3 0.2 6.3e-37 126.1 0.0 1.7 2 0 0 2 2 2 1 TIR domain Ig_2 PF13895.1 KFM05426.1 - 6.1e-17 61.5 0.5 9.5e-08 32.0 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.11 KFM05426.1 - 5.1e-15 55.0 0.0 5.5e-05 22.9 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.20 KFM05426.1 - 2.3e-09 37.2 0.6 0.003 17.6 0.0 3.8 3 1 0 3 3 3 2 Immunoglobulin domain Ig_3 PF13927.1 KFM05426.1 - 7.6e-07 29.5 4.4 0.099 13.1 0.0 3.9 4 1 0 4 4 4 2 Immunoglobulin domain V-set PF07686.12 KFM05426.1 - 7.7e-06 25.7 5.0 0.15 11.9 0.1 4.2 3 2 0 3 3 3 2 Immunoglobulin V-set domain C2-set PF05790.10 KFM05426.1 - 0.14 12.1 0.0 24 4.9 0.0 2.7 2 1 0 2 2 2 0 Immunoglobulin C2-set domain Ig_2 PF13895.1 KFM05427.1 - 8.1e-15 54.7 0.1 4.9e-06 26.5 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.11 KFM05427.1 - 8.2e-12 44.8 0.0 0.00034 20.4 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin I-set domain ig PF00047.20 KFM05427.1 - 4.9e-11 42.6 3.3 0.0057 16.7 0.0 5.0 4 2 0 4 4 4 3 Immunoglobulin domain Ig_3 PF13927.1 KFM05427.1 - 6.3e-07 29.8 1.1 0.021 15.3 0.1 3.9 3 1 0 3 3 3 2 Immunoglobulin domain V-set PF07686.12 KFM05427.1 - 9.9e-07 28.6 2.2 0.05 13.4 0.1 4.0 3 2 0 3 3 3 2 Immunoglobulin V-set domain CNH PF00780.17 KFM05429.1 - 9.4e-60 202.3 0.0 1.6e-59 201.5 0.0 1.4 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.20 KFM05429.1 - 5.8e-57 192.7 0.0 5.8e-57 192.7 0.0 2.2 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM05429.1 - 1.8e-40 138.6 0.0 3.7e-40 137.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase RFX_DNA_binding PF02257.10 KFM05430.1 - 3.2e-17 62.4 0.6 1.4e-16 60.4 0.1 2.1 2 0 0 2 2 2 1 RFX DNA-binding domain FBD PF08387.5 KFM05431.1 - 0.088 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 FBD DUF2704 PF10866.3 KFM05431.1 - 0.094 12.0 0.1 0.13 11.6 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2704) zf-RING_2 PF13639.1 KFM05432.1 - 1.3e-14 53.7 7.2 2e-14 53.1 5.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KFM05432.1 - 4.5e-10 39.4 3.3 9.3e-10 38.4 2.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KFM05432.1 - 7.9e-08 31.8 7.3 1.3e-07 31.1 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM05432.1 - 1.7e-07 30.8 5.1 2.6e-07 30.2 3.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFM05432.1 - 7.3e-07 28.7 4.3 1.1e-06 28.2 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM05432.1 - 8.1e-07 28.9 8.1 1.4e-06 28.1 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UPF0233 PF06781.7 KFM05432.1 - 0.0015 18.0 0.9 0.0029 17.2 0.6 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0233) zf-Apc11 PF12861.2 KFM05432.1 - 0.016 15.0 4.6 0.034 13.9 3.2 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PspB PF06667.7 KFM05432.1 - 0.033 14.1 0.1 0.075 12.9 0.1 1.7 1 0 0 1 1 1 0 Phage shock protein B zf-RING_UBOX PF13445.1 KFM05432.1 - 0.052 13.2 3.7 0.12 12.1 2.6 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_1 PF14446.1 KFM05432.1 - 0.086 12.5 5.2 0.063 13.0 1.2 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Prok-RING_4 PF14447.1 KFM05432.1 - 0.47 10.0 4.8 0.39 10.3 2.2 1.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 FANCL_C PF11793.3 KFM05432.1 - 1.6 8.7 5.7 13 5.7 4.3 2.2 1 1 1 2 2 2 0 FANCL C-terminal domain RINGv PF12906.2 KFM05432.1 - 2.3 8.3 6.2 4.6 7.3 4.3 1.5 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.24 KFM05432.1 - 2.6 7.8 6.1 2.1 8.1 3.2 1.7 2 0 0 2 2 1 0 PHD-finger DUF2363 PF10155.4 KFM05433.1 - 3.2e-54 182.2 6.6 4.5e-54 181.7 4.6 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2363) Ribosomal_L31e PF01198.14 KFM05434.1 - 2.1e-40 136.2 2.8 2.9e-40 135.8 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e Vsr PF03852.10 KFM05434.1 - 0.051 13.1 0.1 0.098 12.2 0.0 1.5 1 1 0 1 1 1 0 DNA mismatch endonuclease Vsr Phosducin PF02114.11 KFM05435.1 - 2.8e-17 62.3 1.1 3.5e-17 61.9 0.5 1.3 1 1 0 1 1 1 1 Phosducin DUF3886 PF13025.1 KFM05435.1 - 0.03 14.2 3.4 0.03 14.2 2.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3886) OmpH PF03938.9 KFM05435.1 - 0.04 13.8 3.5 0.067 13.1 2.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3210 PF11489.3 KFM05435.1 - 0.69 8.5 3.5 0.95 8.0 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3210) Histone PF00125.19 KFM05436.1 - 1.4e-23 82.7 0.0 1.8e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFM05436.1 - 0.00062 19.7 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Sulfotransfer_2 PF03567.9 KFM05437.1 - 1.1e-51 175.9 0.1 1.4e-51 175.6 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase family AF-4 PF05110.8 KFM05438.1 - 1.1e-90 305.1 18.5 9.3e-56 189.4 2.5 2.0 1 1 1 2 2 2 2 AF-4 proto-oncoprotein IMS PF00817.15 KFM05439.1 - 2.4e-42 144.2 0.0 4.3e-42 143.4 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KFM05439.1 - 2.4e-19 69.5 0.0 7.5e-19 67.9 0.0 1.9 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT PF00533.21 KFM05439.1 - 5.4e-08 32.8 0.0 1.3e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF4414 PF14377.1 KFM05439.1 - 4.7e-07 29.6 3.1 0.0045 16.8 0.2 3.3 4 0 0 4 4 4 2 Domain of unknown function (DUF4414) IMS_HHH PF11798.3 KFM05439.1 - 1.3e-05 24.8 0.0 0.0011 18.8 0.0 2.8 2 0 0 2 2 2 1 IMS family HHH motif PTCB-BRCT PF12738.2 KFM05439.1 - 5.2e-05 23.0 0.0 0.00015 21.5 0.0 1.9 1 0 0 1 1 1 1 twin BRCT domain HHH_5 PF14520.1 KFM05439.1 - 0.0028 17.8 0.0 0.0089 16.1 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain Cdd1 PF11731.3 KFM05439.1 - 0.016 15.1 0.0 0.045 13.6 0.0 1.8 1 0 0 1 1 1 0 Pathogenicity locus DUF1805 PF08827.6 KFM05439.1 - 0.13 12.0 0.0 0.38 10.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) GTP_EFTU PF00009.22 KFM05440.1 - 3.1e-33 114.7 0.2 3.1e-33 114.7 0.1 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KFM05440.1 - 2.3e-18 66.0 1.3 4.6e-18 65.1 0.0 2.2 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 KFM05440.1 - 2.4e-10 40.3 4.8 6e-07 29.4 0.2 3.7 2 0 0 2 2 2 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 KFM05440.1 - 3.2e-08 33.0 0.9 8.2e-08 31.7 0.2 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Sec23_helical PF04815.10 KFM05440.1 - 0.092 12.1 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 Sec23/Sec24 helical domain Thioredoxin PF00085.15 KFM05441.1 - 1.8e-10 40.4 0.1 3.8e-10 39.3 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.11 KFM05441.1 - 5.1e-09 35.2 0.4 6.9e-09 34.8 0.3 1.1 1 0 0 1 1 1 1 Phosducin CRF PF00473.12 KFM05441.1 - 0.12 12.5 0.6 2.5 8.2 0.0 2.4 2 0 0 2 2 2 0 Corticotropin-releasing factor family BAG PF02179.11 KFM05441.1 - 0.92 9.6 9.4 0.34 11.0 4.6 1.8 2 0 0 2 2 2 0 BAG domain DUF342 PF03961.8 KFM05441.1 - 1.2 7.4 6.3 1.4 7.2 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) SLT PF01464.15 KFM05442.1 - 7.1e-09 35.1 0.0 1.3e-08 34.3 0.0 1.4 2 0 0 2 2 2 1 Transglycosylase SLT domain SLT PF01464.15 KFM05443.1 - 1e-19 70.2 0.1 1.3e-19 69.9 0.1 1.1 1 0 0 1 1 1 1 Transglycosylase SLT domain SLT_2 PF13406.1 KFM05443.1 - 0.003 16.5 0.0 0.0058 15.5 0.0 1.4 1 0 0 1 1 1 1 Transglycosylase SLT domain Toxin_16 PF07945.6 KFM05443.1 - 0.072 12.7 0.4 0.072 12.7 0.3 1.6 2 0 0 2 2 2 0 Janus-atracotoxin 4_1_CTD PF05902.8 KFM05444.1 - 3.2e-54 181.8 12.5 8.1e-54 180.5 8.7 1.8 1 0 0 1 1 1 1 4.1 protein C-terminal domain (CTD) SAB PF04382.8 KFM05444.1 - 3.4e-27 93.8 8.6 4.5e-27 93.4 2.0 2.7 2 0 0 2 2 2 1 SAB domain FERM_C PF09380.5 KFM05444.1 - 3.8e-23 81.5 0.0 8.1e-23 80.4 0.0 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.5 KFM05444.1 - 2e-21 75.8 0.1 1.1e-20 73.3 0.0 2.3 2 0 0 2 2 2 1 FERM N-terminal domain FA PF08736.6 KFM05444.1 - 6.9e-19 67.3 2.0 1.9e-18 65.9 1.4 1.8 1 0 0 1 1 1 1 FERM adjacent (FA) FERM_M PF00373.13 KFM05444.1 - 3e-18 66.2 1.5 8.3e-18 64.7 0.0 2.4 2 0 0 2 2 2 1 FERM central domain IGFBP PF00219.13 KFM05445.1 - 3.3e-13 49.9 22.3 3.3e-13 49.9 15.4 5.9 3 2 1 4 4 4 1 Insulin-like growth factor binding protein Cys_knot PF00007.17 KFM05445.1 - 4.9e-13 49.0 9.2 4.9e-13 49.0 6.4 3.6 4 0 0 4 4 4 1 Cystine-knot domain TSP_1 PF00090.14 KFM05445.1 - 5.2e-11 42.4 7.3 5.1e-10 39.2 5.0 2.9 1 0 0 1 1 1 1 Thrombospondin type 1 domain VWC PF00093.13 KFM05445.1 - 7.7e-08 32.3 10.1 7.7e-08 32.3 7.0 5.4 4 3 0 4 4 4 1 von Willebrand factor type C domain RRM_1 PF00076.17 KFM05446.1 - 4.3e-24 83.9 0.0 2.3e-12 46.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM05446.1 - 3.4e-13 49.3 0.0 1.8e-05 24.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM05446.1 - 4.6e-09 35.9 0.0 3e-05 23.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.17 KFM05447.1 - 2.8e-26 91.8 0.0 3.2e-26 91.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Sec1 PF00995.18 KFM05447.1 - 0.12 10.9 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Sec1 family TFIID_20kDa PF03847.8 KFM05448.1 - 2.9e-36 123.5 2.8 4.1e-36 123.0 1.9 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 KFM05448.1 - 6.7e-06 26.0 0.2 1.1e-05 25.4 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KFM05448.1 - 2.1e-05 24.5 0.1 3.1e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.10 KFM05448.1 - 0.00081 19.1 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit TAF4 PF05236.9 KFM05448.1 - 0.0047 16.2 0.0 0.0054 16.0 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Condensin2nSMC PF12422.3 KFM05448.1 - 0.023 14.4 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit SAND PF01342.16 KFM05449.1 - 4.6e-35 119.1 0.1 8.1e-35 118.3 0.1 1.4 1 0 0 1 1 1 1 SAND domain DUF948 PF06103.6 KFM05449.1 - 0.0085 15.9 2.9 0.0085 15.9 2.0 2.7 4 0 0 4 4 4 1 Bacterial protein of unknown function (DUF948) Glutenin_hmw PF03157.8 KFM05450.1 - 0.03 12.6 25.5 0.17 10.1 17.7 1.9 1 1 0 1 1 1 0 High molecular weight glutenin subunit E2F_TDP PF02319.15 KFM05451.1 - 2.1e-25 88.0 0.1 3.6e-25 87.3 0.1 1.4 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Caps_synth_GfcC PF06251.6 KFM05451.1 - 0.0035 16.5 0.8 0.0049 16.0 0.5 1.2 1 0 0 1 1 1 1 Capsule biosynthesis GfcC DUF3338 PF11819.3 KFM05451.1 - 0.063 12.7 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3338) ArfGap PF01412.13 KFM05452.1 - 6.3e-25 87.2 0.0 1.6e-23 82.7 0.0 2.8 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 KFM05452.1 - 1.4e-10 41.2 0.7 3.5e-10 40.0 0.2 1.9 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 KFM05452.1 - 0.00035 20.6 0.1 0.94 9.6 0.0 2.6 2 0 0 2 2 2 2 Pleckstrin homology domain Ank_2 PF12796.2 KFM05452.1 - 0.00061 20.0 0.0 0.002 18.4 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFM05452.1 - 0.00093 19.6 0.0 0.0027 18.1 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 KFM05452.1 - 0.0015 18.2 1.0 2.1 8.3 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 KFM05452.1 - 0.0059 16.7 0.5 2.1 8.8 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat PH_3 PF14593.1 KFM05452.1 - 0.0076 16.1 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 PH domain Mcp5_PH PF12814.2 KFM05452.1 - 0.076 12.9 0.1 1.5 8.7 0.0 2.6 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology TFIIS_M PF07500.9 KFM05453.1 - 6.2e-46 155.2 0.3 1.1e-45 154.4 0.2 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 KFM05453.1 - 1.7e-18 65.9 7.2 3e-18 65.1 5.0 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Nitrate_red_del PF02613.10 KFM05453.1 - 0.08 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Nitrate reductase delta subunit MIP-T3 PF10243.4 KFM05453.1 - 8 4.8 17.4 12 4.2 12.0 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 7tm_1 PF00001.16 KFM05454.1 - 2.2e-61 207.2 16.6 2.6e-61 207.0 11.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 KFM05454.1 - 4.9e-07 29.1 9.7 8.9e-07 28.3 6.7 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.4 KFM05454.1 - 5.2e-05 22.5 10.2 0.00023 20.3 6.9 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.4 KFM05454.1 - 7e-05 22.1 13.2 9.8e-05 21.6 9.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Herpes_US9 PF06072.6 KFM05454.1 - 0.091 12.6 0.2 0.091 12.6 0.1 2.8 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 RCC1 PF00415.13 KFM05455.1 - 9.7e-47 156.9 12.7 5.4e-12 45.7 0.1 4.1 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KFM05455.1 - 8.3e-15 53.9 20.9 0.0017 17.9 0.1 5.2 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat CorA PF01544.13 KFM05456.1 - 0.065 12.2 2.7 0.083 11.9 1.7 1.3 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.7 KFM05456.1 - 0.31 10.8 1.8 0.56 10.0 1.2 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.6 KFM05456.1 - 0.91 9.3 16.6 2.1 8.1 11.5 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) GAS PF13851.1 KFM05456.1 - 3.1 6.9 23.6 0.32 10.1 11.4 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3552 PF12072.3 KFM05456.1 - 3.2 6.9 20.2 0.33 10.1 10.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Peptidase_C1 PF00112.18 KFM05457.1 - 1.8e-70 237.2 0.2 2e-70 237.0 0.2 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 KFM05457.1 - 0.00049 18.7 0.1 0.036 12.5 0.0 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.18 KFM05458.1 - 8.2e-72 241.6 3.3 1e-71 241.3 2.3 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 KFM05458.1 - 1.1e-09 38.3 0.0 2e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 KFM05458.1 - 0.0012 17.4 0.1 0.076 11.5 0.0 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Pkinase_Tyr PF07714.12 KFM05459.1 - 1.1e-93 313.0 0.0 1.4e-93 312.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM05459.1 - 2.4e-49 167.8 0.0 3.3e-49 167.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 KFM05459.1 - 1.1e-28 98.7 0.4 2.5e-28 97.6 0.2 1.7 2 0 0 2 2 2 1 SH2 domain SH3_9 PF14604.1 KFM05459.1 - 0.00032 20.2 0.6 0.00066 19.2 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain APH PF01636.18 KFM05459.1 - 0.00087 19.0 0.1 0.23 11.1 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family SH3_1 PF00018.23 KFM05459.1 - 0.0016 17.7 0.3 0.0072 15.6 0.1 2.1 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 KFM05459.1 - 0.002 17.6 0.4 0.0052 16.2 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain WH2 PF02205.15 KFM05460.1 - 2e-08 33.5 0.0 3.8e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 WH2 motif 7tm_1 PF00001.16 KFM05461.1 - 1.1e-38 132.8 23.4 1.4e-38 132.5 16.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pkinase PF00069.20 KFM05462.1 - 8.5e-44 149.6 0.0 1.4e-43 148.9 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM05462.1 - 7.9e-28 97.2 0.0 8.7e-28 97.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM05462.1 - 0.098 11.5 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF778 PF05608.7 KFM05463.1 - 5.9e-41 139.6 2.2 4.9e-40 136.6 1.5 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF778) CTX_RstB PF07459.6 KFM05463.1 - 0.054 13.3 0.0 0.08 12.8 0.0 1.2 1 0 0 1 1 1 0 CTX phage RstB protein eIF-1a PF01176.14 KFM05464.1 - 0.15 11.5 0.1 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 WD40 PF00400.27 KFM05465.1 - 1.9e-34 116.2 3.6 7.3e-08 32.0 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat TPR_11 PF13414.1 KFM05465.1 - 6.7e-17 60.8 11.2 5.7e-14 51.5 2.9 2.5 1 1 1 2 2 2 2 TPR repeat TPR_17 PF13431.1 KFM05465.1 - 1.4e-07 31.1 1.4 0.0056 16.7 0.2 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFM05465.1 - 5.6e-07 29.8 0.7 0.0057 16.9 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFM05465.1 - 5e-06 26.0 9.0 0.042 13.7 0.3 4.1 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KFM05465.1 - 1.2e-05 24.6 10.4 0.11 12.1 0.6 4.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFM05465.1 - 1.7e-05 25.3 2.4 0.02 15.5 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFM05465.1 - 3.1e-05 24.2 0.7 0.16 12.6 0.1 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 KFM05465.1 - 6.3e-05 23.0 4.6 0.00012 22.1 3.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KFM05465.1 - 0.00017 21.8 0.2 0.13 12.7 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFM05465.1 - 0.17 11.7 2.2 0.26 11.1 0.6 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Na_H_Exchanger PF00999.16 KFM05466.1 - 1.5e-82 277.1 43.4 1.9e-82 276.8 30.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family OprF PF05736.6 KFM05466.1 - 0.065 12.7 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 OprF membrane domain DUF1419 PF07215.6 KFM05466.1 - 0.26 11.1 2.0 3.8 7.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1419) DUF1693 PF07984.7 KFM05467.1 - 1.2e-161 537.1 2.2 1.4e-161 536.9 1.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1693) DUF4656 PF15551.1 KFM05468.1 - 8.7e-154 512.1 10.8 9.6e-154 512.0 7.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4656) CS PF04969.11 KFM05469.1 - 3.8e-19 69.0 0.3 1.2e-18 67.4 0.0 2.0 2 0 0 2 2 2 1 CS domain Nudc_N PF14050.1 KFM05469.1 - 1.9e-10 40.5 1.4 4.8e-10 39.2 1.0 1.7 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. 14-3-3 PF00244.15 KFM05470.1 - 9.4e-106 352.1 7.3 1e-105 352.0 5.1 1.0 1 0 0 1 1 1 1 14-3-3 protein His_Phos_2 PF00328.17 KFM05470.1 - 0.012 14.9 0.8 0.013 14.8 0.6 1.1 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) DUF837 PF05769.6 KFM05470.1 - 0.035 13.6 3.2 0.11 12.0 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF837) TPR_12 PF13424.1 KFM05470.1 - 0.044 13.7 0.2 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat FliM PF02154.10 KFM05470.1 - 0.11 12.1 0.1 0.27 10.8 0.0 1.6 2 1 0 2 2 2 0 Flagellar motor switch protein FliM PMEI PF04043.10 KFM05470.1 - 0.12 12.2 1.6 2.3 8.1 0.2 2.2 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor TMCO5 PF14992.1 KFM05470.1 - 0.18 10.9 4.9 0.099 11.7 2.0 1.6 1 1 1 2 2 2 0 TMCO5 family TPR_8 PF13181.1 KFM05470.1 - 0.18 11.6 1.4 0.85 9.5 0.3 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-DHHC PF01529.15 KFM05471.1 - 2.8e-39 134.3 6.9 4.3e-39 133.6 4.8 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF4014 PF13198.1 KFM05471.1 - 1.3 9.4 4.2 1.6 9.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4014) Mannosyl_trans2 PF04188.8 KFM05472.1 - 9e-129 430.2 9.6 1e-128 430.0 6.7 1.0 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) DUF4029 PF13221.1 KFM05472.1 - 0.09 13.1 0.4 0.24 11.8 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4029) DUF3518 PF12031.3 KFM05473.1 - 8.6e-144 477.0 0.1 1.6e-143 476.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3518) ARID PF01388.16 KFM05473.1 - 1e-24 86.1 0.0 2.7e-24 84.8 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Pkinase PF00069.20 KFM05474.1 - 2.6e-147 488.8 0.0 1.7e-73 246.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFM05474.1 - 1.1e-77 260.5 0.0 3.1e-41 141.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KFM05474.1 - 6.2e-16 58.2 0.0 9e-08 31.4 0.0 3.5 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.9 KFM05474.1 - 1.7e-10 40.3 0.0 5.4e-06 25.6 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.19 KFM05474.1 - 2.2e-07 31.2 1.1 7.1e-07 29.6 0.7 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain YrbL-PhoP_reg PF10707.4 KFM05474.1 - 1e-05 24.9 0.0 0.0076 15.6 0.0 2.5 2 0 0 2 2 2 2 PhoP regulatory network protein YrbL APH PF01636.18 KFM05474.1 - 3.1e-05 23.8 0.0 0.2 11.3 0.0 2.7 2 1 0 2 2 2 2 Phosphotransferase enzyme family tRNA-synt_1f PF01921.13 KFM05474.1 - 0.00068 18.4 0.0 0.0012 17.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (K) RIO1 PF01163.17 KFM05474.1 - 0.0097 15.2 0.0 0.39 10.0 0.0 2.5 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.15 KFM05474.1 - 0.11 12.1 0.0 13 5.3 0.0 2.3 2 0 0 2 2 2 0 Choline/ethanolamine kinase HMG14_17 PF01101.13 KFM05475.1 - 1.9e-20 73.3 20.9 2.1e-20 73.1 14.5 1.0 1 0 0 1 1 1 1 HMG14 and HMG17 Prenyltransf PF01255.14 KFM05476.1 - 6.3e-83 277.2 0.0 8.9e-83 276.7 0.0 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase RecX PF02631.11 KFM05476.1 - 2.8 8.1 7.0 5.7 7.1 0.1 2.6 2 1 0 2 2 2 0 RecX family zf-CCHC PF00098.18 KFM05477.1 - 8.3e-07 28.6 11.3 4.4e-05 23.2 2.1 2.3 2 0 0 2 2 2 2 Zinc knuckle CSD PF00313.17 KFM05477.1 - 2.4e-06 27.1 0.0 3.9e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain zf-CCHC_4 PF14392.1 KFM05477.1 - 2.6e-05 23.8 10.2 0.024 14.2 0.8 2.5 2 0 0 2 2 2 2 Zinc knuckle Viral_NABP PF05515.6 KFM05477.1 - 0.086 13.1 1.9 0.13 12.5 1.3 1.3 1 0 0 1 1 1 0 Viral nucleic acid binding CusF_Ec PF11604.3 KFM05477.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Copper binding periplasmic protein CusF zf-CCHC_6 PF15288.1 KFM05477.1 - 0.29 10.8 7.5 4.2 7.1 0.7 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.1 KFM05477.1 - 5.9 6.4 11.7 0.26 10.8 3.8 1.9 1 1 1 2 2 2 0 Zinc knuckle Crystall PF00030.14 KFM05478.1 - 2.5e-129 421.4 0.1 9e-24 83.1 0.0 6.2 6 0 0 6 6 6 6 Beta/Gamma crystallin Ricin_B_lectin PF00652.17 KFM05478.1 - 2.6e-07 30.7 0.0 4.9e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Crystall_3 PF08964.5 KFM05478.1 - 0.00025 20.7 0.2 5 6.9 0.0 5.8 7 0 0 7 7 7 1 Beta/Gamma crystallin RicinB_lectin_2 PF14200.1 KFM05478.1 - 0.0026 18.1 0.0 0.021 15.1 0.0 2.3 1 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like SEP PF08059.8 KFM05479.1 - 5.5e-17 61.8 0.0 1.2e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 KFM05479.1 - 1.3e-09 38.0 0.0 5.1e-08 32.8 0.0 2.7 2 1 0 2 2 2 1 UBX domain Nup54 PF13874.1 KFM05479.1 - 0.0011 18.6 2.2 0.0011 18.6 1.5 1.6 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 TMPIT PF07851.8 KFM05479.1 - 0.011 14.8 1.1 0.017 14.2 0.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein DivIC PF04977.10 KFM05479.1 - 0.052 13.0 2.9 0.16 11.4 2.0 1.8 1 0 0 1 1 1 0 Septum formation initiator DUF573 PF04504.9 KFM05479.1 - 0.11 12.8 1.0 0.3 11.3 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF573 SlyX PF04102.7 KFM05479.1 - 0.11 12.9 5.0 0.37 11.1 2.9 2.5 1 1 0 1 1 1 0 SlyX XhlA PF10779.4 KFM05479.1 - 0.41 10.5 7.1 0.21 11.5 3.2 1.9 2 0 0 2 2 2 0 Haemolysin XhlA SH3BGR PF04908.10 KFM05480.1 - 4.4e-31 106.7 0.1 4.9e-31 106.6 0.1 1.0 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.19 KFM05480.1 - 1.1e-07 31.6 0.0 1.7e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Reo_sigmaC PF04582.7 KFM05481.1 - 0.36 9.9 14.7 0.64 9.1 2.7 3.4 1 1 2 3 3 3 0 Reovirus sigma C capsid protein zf-C2H2_jaz PF12171.3 KFM05483.1 - 0.0069 16.4 0.4 0.0095 16.0 0.3 1.2 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AKAP95 PF04988.7 KFM05483.1 - 0.057 13.2 0.0 0.057 13.2 0.0 1.2 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) Pkinase PF00069.20 KFM05485.1 - 1.5e-52 178.3 0.1 1.2e-51 175.3 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM05485.1 - 1e-32 113.2 0.3 7.7e-23 80.8 0.0 2.8 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KFM05485.1 - 0.014 15.1 0.1 0.071 12.8 0.0 2.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KFM05485.1 - 0.048 12.4 0.0 0.074 11.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 KFM05485.1 - 0.055 12.5 0.0 0.093 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KFM05485.1 - 0.087 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL zf-RING_UBOX PF13445.1 KFM05486.1 - 1.2e-09 37.7 2.5 3.9e-09 36.0 1.7 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 KFM05486.1 - 1.6e-09 37.6 6.0 1.6e-09 37.6 4.1 2.8 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM05486.1 - 1.7e-08 34.1 5.2 1.7e-08 34.1 3.6 2.6 2 1 1 3 3 1 1 Ring finger domain zf-C3HC4 PF00097.20 KFM05486.1 - 5.8e-08 32.2 3.4 5.8e-08 32.2 2.3 3.0 2 2 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM05486.1 - 6.8e-08 32.0 4.9 6.8e-08 32.0 3.4 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM05486.1 - 2.2e-07 30.4 5.0 2.2e-07 30.4 3.5 3.0 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFM05486.1 - 2.6e-06 27.2 6.9 2.6e-06 27.2 4.8 3.1 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-B_box PF00643.19 KFM05486.1 - 4.8e-06 26.3 6.6 4.8e-06 26.3 4.6 4.0 4 0 0 4 4 4 1 B-box zinc finger zf-RING_6 PF14835.1 KFM05486.1 - 0.00018 21.1 0.2 0.00018 21.1 0.2 2.5 2 0 0 2 2 2 1 zf-RING of BARD1-type protein DUF745 PF05335.8 KFM05486.1 - 0.0076 15.7 0.9 0.025 14.1 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF745) zf-MIZ PF02891.15 KFM05486.1 - 0.53 9.8 9.6 5 6.7 6.6 2.5 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger Cation_efflux PF01545.16 KFM05487.1 - 4.4e-34 117.8 2.1 4.8e-34 117.7 1.4 1.0 1 0 0 1 1 1 1 Cation efflux family Chromate_transp PF02417.10 KFM05487.1 - 0.23 11.0 7.2 1.1 8.7 2.1 2.1 1 1 1 2 2 2 0 Chromate transporter EamA PF00892.15 KFM05487.1 - 1.7 8.6 6.4 1.7 8.6 1.0 2.7 2 1 0 2 2 2 0 EamA-like transporter family DUF2975 PF11188.3 KFM05487.1 - 8.7 6.0 8.7 2.9 7.6 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) Exostosin PF03016.10 KFM05488.1 - 3.9e-58 196.8 0.0 5.2e-58 196.4 0.0 1.1 1 0 0 1 1 1 1 Exostosin family Glyco_transf_64 PF09258.5 KFM05488.1 - 9.7e-53 178.8 0.0 1.4e-52 178.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain PAF-AH_p_II PF03403.8 KFM05489.1 - 7e-51 172.6 0.0 7.6e-51 172.5 0.0 1.0 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 KFM05489.1 - 9.1e-06 25.4 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KFM05489.1 - 0.00091 18.7 0.0 0.0011 18.4 0.0 1.1 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.2 KFM05489.1 - 0.0011 18.9 0.0 0.05 13.4 0.1 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFM05489.1 - 0.042 13.0 0.1 0.091 11.9 0.0 1.7 1 1 0 1 1 1 0 Prolyl oligopeptidase family HlyIII PF03006.15 KFM05490.1 - 9.7e-42 142.8 13.3 1.6e-41 142.1 9.2 1.3 1 0 0 1 1 1 1 Haemolysin-III related Mito_fiss_reg PF05308.6 KFM05491.1 - 1.1e-84 283.7 2.8 1.3e-84 283.5 2.0 1.1 1 0 0 1 1 1 1 Mitochondrial fission regulator EF-hand_7 PF13499.1 KFM05492.1 - 0.0055 16.8 0.0 0.014 15.4 0.0 1.7 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KFM05492.1 - 0.023 13.9 0.0 0.065 12.5 0.0 1.8 1 0 0 1 1 1 0 EF hand SPARC_Ca_bdg PF10591.4 KFM05492.1 - 0.023 14.6 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_6 PF13405.1 KFM05492.1 - 0.036 13.9 0.0 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain PID PF00640.18 KFM05494.1 - 6.1e-15 55.4 0.1 7.2e-15 55.1 0.1 1.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID_2 PF14719.1 KFM05494.1 - 6.4e-13 48.7 0.0 7.2e-13 48.5 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.8 KFM05494.1 - 3.2e-07 30.3 0.0 3.8e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine-binding domain MIF PF01187.13 KFM05494.1 - 0.089 12.8 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Macrophage migration inhibitory factor (MIF) Macoilin PF09726.4 KFM05495.1 - 7.9e-297 986.2 17.8 9e-297 986.0 12.3 1.0 1 0 0 1 1 1 1 Transmembrane protein Reo_sigmaC PF04582.7 KFM05495.1 - 0.003 16.8 8.4 0.11 11.6 0.9 2.4 2 0 0 2 2 2 2 Reovirus sigma C capsid protein FtsQ PF03799.10 KFM05495.1 - 0.71 10.0 7.3 5.2 7.2 0.0 3.7 3 2 1 4 4 4 0 Cell division protein FtsQ Mto2_bdg PF12808.2 KFM05495.1 - 1.4 9.0 20.2 1.3 9.2 1.1 4.5 3 1 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region IncA PF04156.9 KFM05495.1 - 4 6.9 49.9 0.83 9.2 13.2 4.4 2 1 2 4 4 4 0 IncA protein FlaC_arch PF05377.6 KFM05495.1 - 5.7 6.9 18.8 3.9 7.4 2.4 4.3 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) Pox_A_type_inc PF04508.7 KFM05495.1 - 6.8 6.7 14.1 5.4 7.0 0.3 5.7 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat Ammonium_transp PF00909.16 KFM05496.1 - 5e-53 179.9 18.5 6.4e-53 179.6 12.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family GWT1 PF06423.7 KFM05496.1 - 0.0031 17.6 0.7 0.0031 17.6 0.5 2.8 3 0 0 3 3 3 1 GWT1 UPF0220 PF05255.6 KFM05497.1 - 9e-52 174.6 3.3 9.9e-52 174.5 2.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF4064 PF13273.1 KFM05497.1 - 0.11 12.6 2.0 0.36 10.9 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) SYF2 PF08231.7 KFM05499.1 - 4e-53 179.6 9.9 4e-53 179.6 6.9 1.5 2 0 0 2 2 2 1 SYF2 splicing factor FUSC-like PF12805.2 KFM05499.1 - 0.0023 16.8 0.2 0.0032 16.4 0.2 1.2 1 0 0 1 1 1 1 FUSC-like inner membrane protein yccS rve_3 PF13683.1 KFM05499.1 - 0.04 13.4 0.2 0.87 9.1 0.0 2.5 2 0 0 2 2 2 0 Integrase core domain XG_FTase PF03254.8 KFM05499.1 - 0.062 11.7 0.4 0.088 11.2 0.3 1.3 1 0 0 1 1 1 0 Xyloglucan fucosyltransferase CENP-Q PF13094.1 KFM05499.1 - 0.74 9.8 11.4 25 4.8 0.0 2.9 1 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Runt PF00853.14 KFM05500.1 - 7.2e-50 167.9 0.5 1.1e-49 167.3 0.3 1.3 1 0 0 1 1 1 1 Runt domain RunxI PF08504.6 KFM05500.1 - 1.9e-46 156.6 6.3 1.9e-46 156.6 4.4 1.9 2 0 0 2 2 2 1 Runx inhibition domain GST_N_3 PF13417.1 KFM05502.1 - 1.2e-07 31.8 0.0 2.3e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFM05502.1 - 1.7e-05 24.5 0.0 3.1e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KFM05502.1 - 5e-05 23.2 0.0 9.4e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KFM05502.1 - 0.00089 19.6 0.0 0.0022 18.4 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KFM05502.1 - 0.0018 18.2 0.2 0.025 14.5 0.1 2.6 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain PWI PF01480.12 KFM05503.1 - 1.5e-30 105.0 0.1 3.3e-30 104.0 0.1 1.6 1 0 0 1 1 1 1 PWI domain ETRAMP PF09716.5 KFM05503.1 - 3.5 7.6 11.0 0.13 12.2 1.5 3.0 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Shisa PF13908.1 KFM05504.1 - 0.004 17.3 0.3 0.0047 17.1 0.2 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Syndecan PF01034.15 KFM05504.1 - 0.0056 16.3 0.2 0.0079 15.8 0.1 1.2 1 0 0 1 1 1 1 Syndecan domain SKG6 PF08693.5 KFM05504.1 - 0.014 14.6 1.4 0.025 13.9 1.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Glycophorin_A PF01102.13 KFM05504.1 - 0.021 14.5 0.1 0.025 14.3 0.1 1.2 1 0 0 1 1 1 0 Glycophorin A DUF1049 PF06305.6 KFM05504.1 - 0.023 14.1 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF2976 PF11190.3 KFM05504.1 - 0.029 13.9 0.1 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) m04gp34like PF12216.3 KFM05504.1 - 0.039 13.2 0.3 0.048 12.9 0.2 1.1 1 0 0 1 1 1 0 Immune evasion protein CbtB PF09489.5 KFM05504.1 - 0.057 13.3 0.4 0.089 12.7 0.3 1.3 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) DUF1705 PF08019.7 KFM05504.1 - 0.067 12.6 0.0 0.075 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1705) Rifin_STEVOR PF02009.11 KFM05504.1 - 0.073 12.7 0.2 0.088 12.4 0.1 1.1 1 0 0 1 1 1 0 Rifin/stevor family Adeno_E3_CR2 PF02439.10 KFM05504.1 - 0.09 12.3 2.2 0.14 11.7 1.5 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 PgaD PF13994.1 KFM05504.1 - 0.1 12.0 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 PgaD-like protein TMEM154 PF15102.1 KFM05504.1 - 0.12 12.1 0.1 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 TMEM154 protein family Fst_toxin PF13955.1 KFM05504.1 - 0.97 9.1 7.7 1.7 8.4 5.3 1.4 1 0 0 1 1 1 0 Toxin Fst, type I toxin-antitoxin system Calcipressin PF04847.7 KFM05505.1 - 2e-58 197.0 1.0 2.7e-58 196.5 0.7 1.2 1 0 0 1 1 1 1 Calcipressin RRM_5 PF13893.1 KFM05505.1 - 0.00035 20.3 0.1 0.00056 19.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFM05505.1 - 0.07 12.7 0.2 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mg_trans_NIPA PF05653.9 KFM05506.1 - 3.1e-71 239.8 20.2 3.8e-71 239.4 14.0 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA CP2 PF04516.10 KFM05507.1 - 3.7e-80 268.3 0.1 5.2e-80 267.8 0.1 1.2 1 0 0 1 1 1 1 CP2 transcription factor Tissue_fac PF01108.12 KFM05508.1 - 2.1e-24 85.3 0.1 3.4e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Tissue factor Interfer-bind PF09294.5 KFM05508.1 - 3.6e-09 36.6 0.1 1.3e-08 34.7 0.0 2.0 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.16 KFM05508.1 - 0.00018 21.5 0.4 0.00068 19.7 0.1 2.1 2 1 0 2 2 2 1 Fibronectin type III domain IL6Ra-bind PF09240.5 KFM05508.1 - 0.0038 17.3 0.0 0.0083 16.2 0.0 1.7 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding Tissue_fac PF01108.12 KFM05509.1 - 7.1e-24 83.6 0.5 7.5e-24 83.5 0.4 1.0 1 0 0 1 1 1 1 Tissue factor fn3 PF00041.16 KFM05510.1 - 5.8e-85 279.5 0.0 3.1e-17 62.4 0.0 6.1 5 0 0 5 5 5 5 Fibronectin type III domain I-set PF07679.11 KFM05510.1 - 1.4e-58 194.7 2.5 6.8e-18 64.3 0.2 6.9 6 0 0 6 6 6 6 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM05510.1 - 5.4e-27 93.7 3.0 7.6e-06 25.9 0.0 6.6 6 0 0 6 6 6 5 Immunoglobulin domain V-set PF07686.12 KFM05510.1 - 1.9e-19 69.6 12.3 8.6e-06 25.6 0.1 8.5 7 2 0 7 7 7 4 Immunoglobulin V-set domain ig PF00047.20 KFM05510.1 - 2.1e-15 56.5 3.4 0.0008 19.4 0.0 5.8 5 0 0 5 5 5 3 Immunoglobulin domain Ig_3 PF13927.1 KFM05510.1 - 5.4e-09 36.4 0.1 0.0068 16.8 0.0 4.2 3 0 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.7 KFM05510.1 - 2.1e-07 30.7 0.1 0.12 12.3 0.0 4.7 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Tissue_fac PF01108.12 KFM05510.1 - 1.4e-06 27.9 0.5 1.9 8.2 0.0 5.1 6 0 0 6 6 6 2 Tissue factor SusE PF14292.1 KFM05510.1 - 0.00072 19.3 0.0 0.69 9.7 0.0 4.0 5 0 0 5 5 5 1 SusE outer membrane protein Lipocalin_7 PF14651.1 KFM05511.1 - 2.7e-32 111.1 0.5 3e-32 111.0 0.3 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin PF00061.18 KFM05511.1 - 2.9e-17 63.0 0.5 3.2e-17 62.8 0.3 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family RRM_1 PF00076.17 KFM05512.1 - 1.5e-10 40.5 0.0 3.4e-10 39.3 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM05512.1 - 1e-08 35.0 0.0 1.6e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM05512.1 - 2.7e-06 27.1 0.0 4.6e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PNRC PF15365.1 KFM05513.1 - 1.7e-17 63.1 6.2 2e-16 59.7 0.5 2.3 2 0 0 2 2 2 2 Proline-rich nuclear receptor coactivator Ribosomal_S20p PF01649.13 KFM05513.1 - 0.0023 18.2 3.4 0.0037 17.5 2.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S20 Med25_SD1 PF11235.3 KFM05513.1 - 0.65 10.2 4.6 0.081 13.2 0.5 1.5 2 0 0 2 2 2 0 Mediator complex subunit 25 synapsin 1 7tm_1 PF00001.16 KFM05514.1 - 3.5e-44 150.8 22.8 5.1e-44 150.3 15.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3671 PF12420.3 KFM05514.1 - 1.7 8.6 10.6 4.1 7.4 0.3 3.6 3 1 0 3 3 3 0 Protein of unknown function Alpha_L_fucos PF01120.12 KFM05515.1 - 2.1e-78 263.6 0.4 2.5e-78 263.4 0.3 1.0 1 0 0 1 1 1 1 Alpha-L-fucosidase HMGL-like PF00682.14 KFM05516.1 - 1.1e-69 234.7 0.1 1.3e-69 234.5 0.1 1.0 1 0 0 1 1 1 1 HMGL-like Terminase_2 PF03592.11 KFM05516.1 - 0.12 12.6 0.1 0.21 11.8 0.1 1.3 1 0 0 1 1 1 0 Terminase small subunit Epimerase_Csub PF13950.1 KFM05517.1 - 4e-30 103.5 0.2 4.7e-30 103.3 0.1 1.1 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit Abhydrolase_2 PF02230.11 KFM05518.1 - 7.9e-85 283.6 0.0 8.8e-85 283.5 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KFM05518.1 - 6.9e-12 45.7 0.0 2.3e-09 37.4 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFM05518.1 - 1.7e-10 40.8 0.1 4.2e-10 39.5 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KFM05518.1 - 1.3e-07 31.3 0.0 2e-06 27.5 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFM05518.1 - 0.00024 20.3 0.1 0.056 12.6 0.0 2.6 2 1 1 3 3 3 1 Prolyl oligopeptidase family FSH1 PF03959.8 KFM05518.1 - 0.00028 20.3 0.0 0.0037 16.7 0.0 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.13 KFM05518.1 - 0.00039 19.7 0.0 0.00059 19.1 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Cutinase PF01083.17 KFM05518.1 - 0.0016 18.1 0.0 0.0063 16.2 0.0 1.8 1 1 1 2 2 2 1 Cutinase DUF2974 PF11187.3 KFM05518.1 - 0.0021 17.4 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.15 KFM05518.1 - 0.028 13.9 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 KFM05518.1 - 0.055 13.0 0.0 0.078 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) AXE1 PF05448.7 KFM05518.1 - 0.18 10.2 0.0 0.34 9.3 0.0 1.5 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) PITH PF06201.8 KFM05519.1 - 9.7e-35 119.5 0.0 1.2e-34 119.2 0.0 1.1 1 0 0 1 1 1 1 PITH domain Elongin_A PF06881.6 KFM05520.1 - 1.5e-34 118.5 0.0 1.5e-34 118.5 0.0 3.4 3 0 0 3 3 3 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Med26 PF08711.6 KFM05520.1 - 4.7e-16 58.0 0.1 8.9e-16 57.1 0.1 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Kelch_1 PF01344.20 KFM05521.1 - 2.7e-43 145.2 4.9 2.7e-10 39.6 0.0 6.6 6 1 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 KFM05521.1 - 5.3e-39 130.8 4.4 6.7e-08 32.3 0.1 5.9 2 1 4 6 6 6 5 Kelch motif BACK PF07707.10 KFM05521.1 - 2e-25 88.6 0.0 3.9e-25 87.6 0.0 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.26 KFM05521.1 - 3.2e-22 78.5 0.3 5.6e-22 77.8 0.2 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_3 PF13415.1 KFM05521.1 - 1.8e-20 72.5 10.5 2.4e-05 24.3 0.0 5.4 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.10 KFM05521.1 - 1.3e-18 65.9 2.4 7.8e-06 25.4 0.0 6.1 6 1 0 6 6 6 3 Kelch motif Kelch_4 PF13418.1 KFM05521.1 - 3e-17 62.1 3.7 4.2e-05 23.2 0.0 5.8 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 KFM05521.1 - 6.4e-12 45.1 2.2 0.071 13.0 0.0 4.7 4 0 0 4 4 4 4 Kelch motif Ribosomal_L5_C PF00673.16 KFM05522.1 - 2.1e-23 81.8 0.0 3e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 KFM05522.1 - 7.8e-21 73.6 0.1 2.5e-19 68.8 0.0 2.4 2 0 0 2 2 2 1 Ribosomal protein L5 Palm_thioest PF02089.10 KFM05523.1 - 1e-151 503.6 0.0 1.1e-151 503.4 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.15 KFM05523.1 - 0.1 12.1 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold CAP_N PF01213.14 KFM05524.1 - 1.3e-110 369.6 7.4 2.5e-108 362.0 5.1 2.1 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 KFM05524.1 - 4.4e-68 227.6 4.0 6.2e-68 227.1 2.8 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 KFM05524.1 - 8.6e-06 25.1 2.1 1.4e-05 24.4 1.0 1.5 1 1 0 1 1 1 1 Tubulin binding cofactor C RE_Bsp6I PF09504.5 KFM05524.1 - 0.035 13.5 0.0 0.1 12.0 0.0 1.7 2 0 0 2 2 2 0 Bsp6I restriction endonuclease WH2 PF02205.15 KFM05524.1 - 0.044 13.3 0.1 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 WH2 motif MFS_2 PF13347.1 KFM05525.1 - 1.9e-81 273.6 20.6 3.8e-81 272.6 14.3 1.4 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.11 KFM05525.1 - 5e-09 35.3 18.3 4.5e-08 32.1 11.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Myc_N PF01056.13 KFM05526.1 - 9.2e-44 149.9 7.0 1.1e-30 107.0 1.4 3.4 1 1 1 2 2 2 2 Myc amino-terminal region HLH PF00010.21 KFM05526.1 - 4e-13 48.8 0.2 1.5e-12 46.9 0.2 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain IPPT PF01715.12 KFM05527.1 - 2.5e-55 187.2 0.1 3.7e-55 186.6 0.0 1.2 1 0 0 1 1 1 1 IPP transferase zf-C2H2_jaz PF12171.3 KFM05527.1 - 5e-05 23.3 0.0 9.5e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM05527.1 - 0.0065 16.6 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Mst1_SARAH PF11629.3 KFM05527.1 - 4 7.3 6.1 6.4 6.6 0.0 3.0 3 1 0 3 3 3 0 C terminal SARAH domain of Mst1 zf-C2H2_6 PF13912.1 KFM05528.1 - 1.8e-31 107.0 47.0 7.2e-08 32.0 0.9 7.6 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM05528.1 - 1.9e-10 40.5 42.6 0.049 13.7 0.3 8.2 7 0 0 7 7 7 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM05528.1 - 7.6e-08 32.3 53.0 0.0045 17.1 0.4 8.8 8 1 0 8 8 8 5 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 KFM05528.1 - 1.6e-06 28.1 64.4 0.011 16.0 0.2 8.7 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM05528.1 - 0.011 16.0 53.3 0.015 15.6 0.2 9.0 9 0 0 9 9 9 0 C2H2-type zinc finger CUB PF00431.15 KFM05529.1 - 3.2e-47 159.1 0.7 3.7e-25 88.1 0.0 2.7 3 0 0 3 3 3 2 CUB domain Ldl_recept_a PF00057.13 KFM05529.1 - 2.8e-35 119.9 87.9 2.4e-11 43.3 10.1 5.6 5 0 0 5 5 5 5 Low-density lipoprotein receptor domain class A Amidohydro_1 PF01979.15 KFM05530.1 - 5.7e-23 82.1 0.0 8.9e-23 81.4 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KFM05530.1 - 2.2e-16 60.7 0.0 4e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KFM05530.1 - 1.8e-12 46.9 0.5 5.6e-12 45.3 0.1 2.1 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 KFM05530.1 - 5.2e-08 32.5 0.4 0.00011 21.5 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_2 PF04909.9 KFM05530.1 - 7.3e-06 25.7 0.0 1.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase DUF497 PF04365.8 KFM05530.1 - 0.05 13.5 0.1 0.33 10.9 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF497) DC_STAMP PF07782.8 KFM05531.1 - 1.9e-42 145.0 1.6 3.1e-42 144.3 1.1 1.4 1 0 0 1 1 1 1 DC-STAMP-like protein SecE PF00584.15 KFM05531.1 - 1.5 8.4 11.1 4.2 7.0 0.5 3.8 4 0 0 4 4 4 0 SecE/Sec61-gamma subunits of protein translocation complex 7tm_4 PF13853.1 KFM05532.1 - 6.7e-38 129.7 10.2 6.7e-38 129.7 7.1 2.5 3 0 0 3 3 3 1 Olfactory receptor 7tm_1 PF00001.16 KFM05532.1 - 3.7e-32 111.4 15.4 4.6e-32 111.1 10.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM05532.1 - 0.0058 15.8 16.4 0.013 14.6 11.4 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx SH2 PF00017.19 KFM05533.1 - 2.6e-18 65.5 0.1 3.9e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 SH2 domain Excalibur PF05901.6 KFM05533.1 - 0.095 13.0 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 Excalibur calcium-binding domain Nucleos_tra2_C PF07662.8 KFM05534.1 - 2.1e-71 239.7 6.1 5.7e-71 238.3 4.2 1.8 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 KFM05534.1 - 4.7e-19 68.5 3.5 4.7e-19 68.5 2.4 3.3 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 KFM05534.1 - 1.2e-07 31.5 9.5 1.2e-07 31.5 6.6 3.9 3 2 0 3 3 3 1 Nucleoside recognition Alpha_kinase PF02816.13 KFM05535.1 - 8.7e-38 129.8 0.0 1.3e-37 129.2 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family I-set PF07679.11 KFM05535.1 - 7.6e-24 83.3 0.4 5.4e-16 58.2 0.0 2.9 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM05535.1 - 8.2e-14 51.4 1.4 2.7e-07 30.5 0.1 3.3 3 0 0 3 3 3 2 Immunoglobulin domain Ig_3 PF13927.1 KFM05535.1 - 1.9e-06 28.2 0.0 0.014 15.8 0.0 3.0 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.12 KFM05535.1 - 0.00039 20.2 1.0 1.6 8.6 0.1 3.2 2 2 0 2 2 2 2 Immunoglobulin V-set domain ig PF00047.20 KFM05535.1 - 0.0012 18.8 0.1 0.013 15.6 0.1 2.6 2 1 0 2 2 2 1 Immunoglobulin domain C2-set_2 PF08205.7 KFM05535.1 - 0.0059 16.4 0.0 0.03 14.2 0.0 2.2 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Adeno_E3_CR1 PF02440.10 KFM05535.1 - 0.0082 15.6 0.0 0.023 14.1 0.0 1.7 1 0 0 1 1 1 1 Adenovirus E3 region protein CR1 Peptidase_C14 PF00656.17 KFM05536.1 - 3.5e-21 76.0 0.0 3.9e-20 72.5 0.0 2.0 1 1 0 1 1 1 1 Caspase domain DUF4254 PF14063.1 KFM05536.1 - 0.07 12.7 0.3 0.55 9.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4254) Peptidase_S24 PF00717.18 KFM05537.1 - 6.4e-10 38.5 0.1 1.6e-09 37.2 0.0 1.5 1 1 0 1 1 1 1 Peptidase S24-like DUF504 PF04457.7 KFM05537.1 - 0.15 12.2 1.4 0.3 11.2 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF504) Bombesin PF02044.12 KFM05538.1 - 1.1e-09 37.3 1.6 1.9e-09 36.6 1.1 1.4 1 0 0 1 1 1 1 Bombesin-like peptide DuoxA PF10204.4 KFM05539.1 - 1.2e-108 362.4 3.5 1.4e-108 362.2 2.4 1.0 1 0 0 1 1 1 1 Dual oxidase maturation factor DUF4191 PF13829.1 KFM05539.1 - 1.8 7.6 6.9 6.4 5.8 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DuoxA PF10204.4 KFM05540.1 - 2.9e-112 374.3 9.6 3.3e-112 374.1 6.7 1.0 1 0 0 1 1 1 1 Dual oxidase maturation factor DUF2207 PF09972.4 KFM05540.1 - 1.2 7.5 10.0 1.7 7.1 0.5 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) VIT1 PF01988.14 KFM05540.1 - 4.3 6.7 9.3 0.46 9.9 1.0 2.3 2 0 0 2 2 2 0 VIT family An_peroxidase PF03098.10 KFM05541.1 - 3.5e-138 461.3 0.0 4.6e-138 460.8 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase NAD_binding_6 PF08030.7 KFM05541.1 - 2.3e-30 105.5 0.0 5.5e-30 104.3 0.0 1.7 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KFM05541.1 - 5.8e-19 67.9 0.0 1.5e-18 66.6 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KFM05541.1 - 3.9e-17 62.5 15.4 1.3e-16 60.8 10.7 2.0 1 0 0 1 1 1 1 Ferric reductase like transmembrane component EF-hand_1 PF00036.27 KFM05541.1 - 8.6e-14 49.7 5.2 3.8e-06 25.8 0.3 3.0 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 KFM05541.1 - 2.9e-10 40.1 10.7 1.6e-08 34.5 1.4 2.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KFM05541.1 - 3.3e-09 35.8 4.9 0.00088 18.9 0.1 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 KFM05541.1 - 2.4e-08 33.4 5.9 3.6e-07 29.6 0.5 3.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 KFM05541.1 - 5e-07 28.7 2.1 0.012 14.9 0.1 2.8 2 0 0 2 2 2 2 EF hand NAD_binding_1 PF00175.16 KFM05541.1 - 1.1e-05 26.0 0.4 0.018 15.6 0.0 3.5 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KFM05541.1 - 0.0049 16.9 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain ADH_zinc_N PF00107.21 KFM05542.1 - 2.3e-24 85.4 0.6 4.4e-24 84.4 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFM05542.1 - 2.7e-24 85.0 0.9 5.5e-24 84.0 0.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF281 PF03436.8 KFM05542.1 - 0.035 14.1 0.9 0.12 12.3 0.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF281) ADH_zinc_N_2 PF13602.1 KFM05542.1 - 0.057 14.3 0.0 0.11 13.4 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase DUF2249 PF10006.4 KFM05542.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) RRM_1 PF00076.17 KFM05543.1 - 3.7e-12 45.6 0.0 7.5e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM05543.1 - 1.4e-05 24.7 0.0 2.8e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM05543.1 - 0.00013 21.9 0.0 0.00026 20.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ASCH PF04266.9 KFM05545.1 - 3.3e-20 72.4 0.0 6.9e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 ASCH domain zf-C2HC5 PF06221.8 KFM05545.1 - 9.8e-18 63.6 11.3 1.2e-17 63.3 7.2 1.7 2 0 0 2 2 2 1 Putative zinc finger motif, C2HC5-type Pkinase PF00069.20 KFM05546.1 - 6.8e-35 120.4 0.0 9.4e-35 120.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain CK1gamma_C PF12605.3 KFM05546.1 - 5.2e-31 107.0 6.0 1e-30 106.1 4.1 1.5 1 0 0 1 1 1 1 Casein kinase 1 gamma C terminal Pkinase_Tyr PF07714.12 KFM05546.1 - 2.4e-14 53.0 0.0 3.2e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 KFM05546.1 - 0.031 13.5 0.0 0.12 11.6 0.0 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL PIP49_C PF12260.3 KFM05546.1 - 0.17 11.3 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Pro_isomerase PF00160.16 KFM05547.1 - 1.3e-41 142.3 0.4 1.5e-41 142.1 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PX PF00787.19 KFM05548.1 - 4.4e-06 26.4 0.1 5.8e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 KFM05549.1 - 6.3e-84 280.9 21.2 6.3e-84 280.9 14.7 1.5 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.19 KFM05549.1 - 2e-28 98.4 0.9 7.8e-28 96.5 0.0 2.2 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.4 KFM05549.1 - 5.4e-05 22.5 3.9 0.0066 15.7 2.7 2.4 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein HR1 PF02185.11 KFM05549.1 - 0.027 14.2 5.0 0.5 10.1 0.5 3.0 2 0 0 2 2 2 0 Hr1 repeat Glyco_hydro_48 PF02011.10 KFM05549.1 - 0.03 12.4 0.4 0.046 11.8 0.3 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 48 Lipase_chap PF03280.9 KFM05549.1 - 0.16 11.4 16.5 0.023 14.2 7.1 2.7 2 1 1 3 3 3 0 Proteobacterial lipase chaperone protein FUSC PF04632.7 KFM05549.1 - 0.2 10.0 3.6 0.29 9.5 2.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2833 PF11090.3 KFM05549.1 - 0.35 11.0 2.3 0.43 10.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2833) DivIC PF04977.10 KFM05549.1 - 0.66 9.5 7.9 1.9 8.0 1.4 2.9 2 0 0 2 2 2 0 Septum formation initiator Arfaptin PF06456.8 KFM05549.1 - 1.4 8.2 13.5 0.033 13.5 2.4 2.4 2 0 0 2 2 2 0 Arfaptin-like domain TBPIP PF07106.8 KFM05549.1 - 2.7 7.5 16.9 0.32 10.5 3.9 2.5 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) H-kinase_dim PF02895.9 KFM05549.1 - 2.9 8.2 6.2 3.5 8.0 1.1 2.8 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain SPT16 PF08644.6 KFM05549.1 - 4.3 7.1 6.5 18 5.1 0.1 2.6 2 1 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) OmpH PF03938.9 KFM05549.1 - 8.4 6.3 13.6 20 5.1 5.6 2.9 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) C1-set PF07654.10 KFM05550.1 - 2.1e-21 75.7 0.0 2.4e-21 75.5 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin C1-set domain I-set PF07679.11 KFM05550.1 - 0.00042 20.1 0.0 0.00049 19.8 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain C2-set_2 PF08205.7 KFM05550.1 - 0.00096 19.0 0.0 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.1 KFM05550.1 - 0.0013 18.7 0.0 0.0017 18.4 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain DUF4557 PF15101.1 KFM05551.1 - 6.4e-09 35.9 0.0 7.1e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4557) Ribosomal_S17e PF00833.13 KFM05552.1 - 1.3e-29 102.4 0.1 1.5e-29 102.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal S17 DUF1858 PF08984.6 KFM05552.1 - 0.1 12.2 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1858) RRM_1 PF00076.17 KFM05553.1 - 1.3e-08 34.3 0.0 0.0065 16.0 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM05553.1 - 1.2e-05 25.1 0.0 3.6e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-B_box PF00643.19 KFM05553.1 - 0.58 10.1 7.3 1.2 9.1 5.1 1.4 1 0 0 1 1 1 0 B-box zinc finger Rep_fac_C PF08542.6 KFM05554.1 - 1.4e-22 79.4 0.1 4.2e-22 77.9 0.1 1.8 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.24 KFM05554.1 - 7.3e-16 58.5 0.0 1.4e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KFM05554.1 - 1.5e-15 57.2 0.0 9.3e-13 48.1 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 KFM05554.1 - 2e-09 36.7 0.0 1.4e-05 24.0 0.0 2.2 1 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KFM05554.1 - 3.8e-07 30.2 0.2 0.0051 16.9 0.0 2.9 2 1 1 3 3 3 2 AAA domain AAA_19 PF13245.1 KFM05554.1 - 2e-06 27.4 0.0 4.8e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KFM05554.1 - 2.5e-06 27.6 0.0 7.4e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.1 KFM05554.1 - 1e-05 25.2 0.0 0.00027 20.5 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 KFM05554.1 - 1.7e-05 24.7 0.0 2.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 KFM05554.1 - 5.2e-05 22.9 0.0 8.3e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KFM05554.1 - 0.00012 21.1 0.0 0.00025 20.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DNA_pol3_delta PF06144.8 KFM05554.1 - 0.00048 19.6 0.0 0.00084 18.8 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_5 PF07728.9 KFM05554.1 - 0.0005 19.8 0.2 0.0034 17.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 KFM05554.1 - 0.00064 18.7 0.0 0.0011 18.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DEAD PF00270.24 KFM05554.1 - 0.00088 18.8 0.1 0.025 14.0 0.0 2.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_25 PF13481.1 KFM05554.1 - 0.0011 18.3 0.0 0.023 14.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 KFM05554.1 - 0.0013 17.5 0.0 0.016 13.9 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus IstB_IS21 PF01695.12 KFM05554.1 - 0.0022 17.4 0.0 0.39 10.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein PhoH PF02562.11 KFM05554.1 - 0.0027 16.9 0.1 0.14 11.3 0.0 2.5 1 1 1 2 2 2 1 PhoH-like protein AAA_30 PF13604.1 KFM05554.1 - 0.0038 16.8 0.1 0.39 10.2 0.0 2.4 2 1 0 3 3 2 1 AAA domain ResIII PF04851.10 KFM05554.1 - 0.0041 16.9 0.0 0.055 13.3 0.0 2.3 2 1 1 3 3 2 1 Type III restriction enzyme, res subunit AAA_10 PF12846.2 KFM05554.1 - 0.017 14.5 0.1 4.7 6.5 0.0 2.4 1 1 1 2 2 2 0 AAA-like domain Mg_chelatase PF01078.16 KFM05554.1 - 0.038 13.1 0.0 0.57 9.3 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI SNF2_N PF00176.18 KFM05554.1 - 0.046 12.5 0.0 0.65 8.7 0.0 2.2 2 0 0 2 2 2 0 SNF2 family N-terminal domain Arch_ATPase PF01637.13 KFM05554.1 - 0.06 13.0 0.0 0.1 12.2 0.0 1.4 1 1 0 1 1 1 0 Archaeal ATPase NB-ARC PF00931.17 KFM05554.1 - 0.072 11.9 0.0 0.78 8.5 0.0 2.2 2 1 0 2 2 2 0 NB-ARC domain AAA_3 PF07726.6 KFM05554.1 - 0.073 12.6 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KFM05554.1 - 0.12 13.2 0.0 0.27 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain zf-RING_2 PF13639.1 KFM05555.1 - 2.5e-07 30.4 2.3 7.7e-07 28.8 1.6 1.9 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KFM05555.1 - 2.7e-06 27.3 0.5 9.3e-06 25.6 0.1 1.9 1 1 1 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KFM05555.1 - 6.7e-06 25.6 1.1 1.7e-05 24.3 0.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM05555.1 - 0.00023 20.8 1.0 0.00053 19.6 0.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFM05555.1 - 0.0039 17.1 6.0 0.012 15.5 0.4 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFM05555.1 - 0.0046 16.7 1.9 0.013 15.2 0.7 2.2 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 KFM05555.1 - 0.0064 16.1 2.2 0.039 13.6 1.5 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-LITAF-like PF10601.4 KFM05555.1 - 0.0079 16.0 0.5 0.0079 16.0 0.4 2.0 2 1 0 2 2 2 1 LITAF-like zinc ribbon domain PHD PF00628.24 KFM05555.1 - 0.1 12.3 1.8 0.11 12.2 0.1 1.8 2 0 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.1 KFM05555.1 - 0.25 11.0 4.2 3.2 7.5 0.0 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.1 KFM05555.1 - 0.27 10.8 2.2 0.29 10.7 0.3 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 KFM05555.1 - 0.33 10.8 3.6 0.34 10.8 0.7 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 KFM05555.1 - 0.35 10.8 2.6 1.1 9.2 1.8 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain ADK_lid PF05191.9 KFM05555.1 - 6.4 6.5 11.6 22 4.8 0.1 4.2 4 0 0 4 4 4 0 Adenylate kinase, active site lid RRM_1 PF00076.17 KFM05556.1 - 7.6e-11 41.4 0.1 3.8e-10 39.2 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM05556.1 - 1.9e-09 37.3 0.0 3.3e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM05556.1 - 0.0028 17.4 0.0 0.0053 16.5 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Adaptin_N PF01602.15 KFM05557.1 - 2.3e-172 574.0 16.0 3e-172 573.6 11.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KFM05557.1 - 5.6e-37 127.3 8.6 1.6e-35 122.5 0.3 4.1 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.5 KFM05557.1 - 6.2e-28 96.9 0.1 1.8e-27 95.4 0.1 1.9 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.1 KFM05557.1 - 5.3e-24 84.3 5.1 1e-06 28.9 0.0 5.7 2 2 4 6 6 6 5 HEAT repeats HEAT PF02985.17 KFM05557.1 - 3.4e-14 51.5 6.2 0.0037 17.2 0.0 6.5 6 0 0 6 6 6 3 HEAT repeat Alpha_adaptinC2 PF02883.15 KFM05557.1 - 2.5e-10 40.6 0.1 6.6e-10 39.3 0.1 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd3 PF12719.2 KFM05557.1 - 3.6e-07 29.4 4.6 2.5e-05 23.4 0.2 2.7 2 1 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain Arm PF00514.18 KFM05557.1 - 7e-07 28.8 5.5 0.0038 17.0 0.0 5.2 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 KFM05557.1 - 3.4e-05 23.3 1.9 0.99 8.7 0.0 4.5 2 2 2 4 4 4 2 CLASP N terminal HEAT_EZ PF13513.1 KFM05557.1 - 9.2e-05 22.8 7.8 1.2 9.6 0.0 6.8 6 2 3 9 9 8 1 HEAT-like repeat MOR2-PAG1_C PF14225.1 KFM05557.1 - 0.0012 18.6 4.3 2.5 7.7 0.0 3.3 2 1 1 3 3 3 2 Cell morphogenesis C-terminal DUF2435 PF10363.4 KFM05557.1 - 0.0035 17.2 3.9 8.5 6.3 0.0 5.3 4 1 1 5 5 5 1 Protein of unknown function (DUF2435) Atx10homo_assoc PF09759.4 KFM05557.1 - 0.0072 16.0 0.1 1.3 8.8 0.0 3.2 2 1 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Cohesin_HEAT PF12765.2 KFM05557.1 - 0.011 15.6 0.0 22 5.1 0.0 4.2 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion FANCI_S2 PF14676.1 KFM05557.1 - 0.099 12.5 1.1 2 8.2 0.2 3.3 3 2 1 4 4 4 0 FANCI solenoid 2 Filament PF00038.16 KFM05558.1 - 2.1e-37 129.2 15.1 2.1e-37 129.2 10.5 2.6 3 0 0 3 3 3 1 Intermediate filament protein FimP PF09766.4 KFM05559.1 - 2.6e-128 428.0 5.7 4.2e-128 427.3 4.0 1.2 1 0 0 1 1 1 1 Fms-interacting protein FERM_C PF09380.5 KFM05560.1 - 1.5e-35 121.2 0.4 3.2e-35 120.1 0.0 1.8 2 0 0 2 2 2 1 FERM C-terminal PH-like domain FERM_M PF00373.13 KFM05560.1 - 1.4e-24 86.6 1.0 1.4e-24 86.6 0.7 2.9 2 1 0 2 2 2 1 FERM central domain ERM PF00769.14 KFM05560.1 - 3.4e-24 85.7 46.9 3.4e-24 85.7 32.5 2.2 2 0 0 2 2 2 1 Ezrin/radixin/moesin family FERM_N PF09379.5 KFM05560.1 - 9.1e-13 48.0 0.2 9.1e-13 48.0 0.1 2.7 3 1 0 3 3 3 1 FERM N-terminal domain DUF956 PF06115.6 KFM05560.1 - 0.09 12.3 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF956) zf-CCCH PF00642.19 KFM05561.1 - 1.8e-08 33.8 2.3 2.8e-08 33.2 1.6 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-U1 PF06220.7 KFM05561.1 - 1.8e-07 30.5 4.2 3.3e-07 29.7 2.9 1.4 1 0 0 1 1 1 1 U1 zinc finger DUF4239 PF14023.1 KFM05561.1 - 0.083 12.2 0.1 0.14 11.4 0.0 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) zf-C2H2_jaz PF12171.3 KFM05561.1 - 0.19 11.8 7.6 1 9.6 5.3 2.2 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-CCCH_2 PF14608.1 KFM05561.1 - 1.3 9.1 4.1 4.4 7.4 2.9 1.9 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Myotub-related PF06602.9 KFM05562.1 - 3.2e-147 489.9 0.2 4.8e-147 489.3 0.1 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.22 KFM05562.1 - 0.00014 21.2 0.0 0.00025 20.4 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFM05562.1 - 0.002 17.6 0.0 0.0045 16.5 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFM05562.1 - 0.0025 18.0 0.0 0.0048 17.1 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Acyl-CoA_dh_1 PF00441.19 KFM05563.1 - 8.3e-29 100.6 0.6 8.3e-29 100.6 0.4 2.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KFM05563.1 - 9.8e-10 37.8 0.2 1.9e-09 36.8 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KFM05563.1 - 1.8e-09 37.9 3.3 4.5e-09 36.6 0.0 2.7 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain HORMA PF02301.13 KFM05564.1 - 1.1e-50 172.0 0.0 1.4e-50 171.7 0.0 1.1 1 0 0 1 1 1 1 HORMA domain LIF_OSM PF01291.12 KFM05565.1 - 9.2e-27 93.9 0.6 1e-26 93.8 0.4 1.0 1 0 0 1 1 1 1 LIF / OSM family PqqD PF05402.7 KFM05565.1 - 0.016 15.1 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) ACT_7 PF13840.1 KFM05566.1 - 2.3e-18 65.4 0.1 5.2e-18 64.3 0.1 1.7 2 0 0 2 2 2 1 ACT domain RabGAP-TBC PF00566.13 KFM05567.1 - 2.9e-54 183.7 0.0 4.3e-54 183.2 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain LRRCT PF01463.19 KFM05567.1 - 0.079 13.2 0.8 39 4.9 0.0 3.4 3 0 0 3 3 3 0 Leucine rich repeat C-terminal domain CENP-F_leu_zip PF10473.4 KFM05568.1 - 0.00013 21.8 70.1 0.0077 16.1 11.2 4.5 2 1 2 4 4 4 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HOOK PF05622.7 KFM05568.1 - 0.023 12.5 50.9 0.035 11.9 35.3 1.3 1 0 0 1 1 1 0 HOOK protein GAS PF13851.1 KFM05568.1 - 0.18 10.9 67.2 0.71 9.0 13.7 4.2 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding DUF2400 PF09674.5 KFM05568.1 - 0.84 9.2 13.4 0.19 11.3 2.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2400) APG6 PF04111.7 KFM05568.1 - 2.1 7.3 61.7 0.071 12.1 17.8 3.3 1 1 2 4 4 4 0 Autophagy protein Apg6 zf-RING_2 PF13639.1 KFM05569.1 - 2.3e-14 52.9 8.2 4.9e-14 51.8 5.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KFM05569.1 - 1.1e-07 31.3 4.3 2.4e-07 30.3 3.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM05569.1 - 1.2e-06 28.1 2.3 2.2e-06 27.2 1.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM05569.1 - 1.5e-06 27.7 3.7 2.9e-06 26.9 2.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KFM05569.1 - 3.1e-06 27.2 9.5 1.1e-05 25.3 6.6 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KFM05569.1 - 3.8e-06 26.8 5.8 9e-06 25.6 4.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FtsL PF04999.8 KFM05569.1 - 0.025 14.2 0.3 0.052 13.2 0.2 1.5 1 0 0 1 1 1 0 Cell division protein FtsL zf-Apc11 PF12861.2 KFM05569.1 - 0.032 14.0 4.0 0.081 12.7 2.8 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Conotoxin PF02950.12 KFM05569.1 - 0.053 14.3 0.3 0.053 14.3 0.2 2.1 2 0 0 2 2 2 0 Conotoxin Mod_r PF07200.8 KFM05570.1 - 5.9e-14 52.2 0.1 6.5e-14 52.0 0.0 1.0 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein WBS_methylT PF12589.3 KFM05571.1 - 2.9e-23 82.1 9.0 4.3e-23 81.5 6.3 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 KFM05571.1 - 6.7e-11 42.5 0.0 1.1e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFM05571.1 - 1.6e-06 28.4 0.0 2.9e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFM05571.1 - 1e-05 26.0 0.0 1.9e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFM05571.1 - 0.00021 21.6 0.0 0.00036 20.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFM05571.1 - 0.00041 20.0 0.0 0.00079 19.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFM05571.1 - 0.00052 19.6 0.0 0.00068 19.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFM05571.1 - 0.0041 17.1 0.0 0.0085 16.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.8 KFM05571.1 - 0.16 12.1 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Syntaxin PF00804.20 KFM05572.1 - 4.7e-48 161.6 8.0 4.7e-48 161.6 5.5 2.5 2 1 0 2 2 2 1 Syntaxin SNARE PF05739.14 KFM05572.1 - 1.1e-24 85.9 1.5 1.1e-24 85.9 1.1 3.2 3 1 0 3 3 3 1 SNARE domain Syntaxin_2 PF14523.1 KFM05572.1 - 5.1e-06 26.4 13.1 2e-05 24.5 6.1 3.1 2 2 1 3 3 3 1 Syntaxin-like protein GNVR PF13807.1 KFM05572.1 - 0.0041 16.8 0.1 0.022 14.4 0.0 2.1 2 0 0 2 2 2 1 G-rich domain on putative tyrosine kinase MCPsignal PF00015.16 KFM05572.1 - 0.0074 15.8 7.6 0.22 11.0 0.6 2.4 2 0 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF148 PF02520.12 KFM05572.1 - 0.0075 16.0 1.5 0.0075 16.0 1.0 2.5 3 0 0 3 3 2 1 Domain of unknown function DUF148 Laminin_II PF06009.7 KFM05572.1 - 0.0096 15.6 1.6 0.0096 15.6 1.1 2.4 2 1 0 2 2 2 1 Laminin Domain II DUF948 PF06103.6 KFM05572.1 - 0.027 14.3 3.0 5.4 6.9 0.4 3.7 3 2 0 3 3 3 0 Bacterial protein of unknown function (DUF948) SIMPL PF04402.9 KFM05572.1 - 0.052 13.3 2.3 0.11 12.3 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF541) Ferritin PF00210.19 KFM05572.1 - 0.059 13.1 3.5 0.034 13.8 0.8 1.8 2 0 0 2 2 2 0 Ferritin-like domain Lzipper-MIP1 PF14389.1 KFM05572.1 - 0.064 13.3 2.7 0.12 12.5 0.0 2.4 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 ApoLp-III PF07464.6 KFM05572.1 - 0.065 13.2 10.0 0.074 13.0 2.9 2.9 1 1 2 3 3 2 0 Apolipophorin-III precursor (apoLp-III) WXG100 PF06013.7 KFM05572.1 - 0.071 13.1 2.8 2.3 8.3 0.1 3.4 4 0 0 4 4 3 0 Proteins of 100 residues with WXG DUF966 PF06136.8 KFM05572.1 - 0.13 11.6 8.6 0.13 11.6 5.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF966) DUF479 PF04336.7 KFM05572.1 - 0.15 12.1 3.2 12 6.0 0.1 3.0 1 1 0 2 2 2 0 Protein of unknown function, DUF479 AATF-Che1 PF13339.1 KFM05572.1 - 0.25 11.4 10.1 0.23 11.5 4.2 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor PspA_IM30 PF04012.7 KFM05572.1 - 0.31 10.3 10.4 0.06 12.7 3.4 2.2 2 1 1 3 3 3 0 PspA/IM30 family DUF1664 PF07889.7 KFM05572.1 - 0.33 10.7 11.7 0.45 10.3 2.0 3.1 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) ETRAMP PF09716.5 KFM05572.1 - 0.48 10.4 4.5 0.57 10.1 0.0 2.6 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Med9 PF07544.8 KFM05572.1 - 0.57 9.9 7.6 0.36 10.6 0.7 3.2 2 2 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 LOH1CR12 PF10158.4 KFM05572.1 - 0.58 9.9 7.7 4.8 6.9 0.5 2.6 2 1 0 2 2 2 0 Tumour suppressor protein Syntaxin-6_N PF09177.6 KFM05572.1 - 0.63 10.4 12.6 0.25 11.7 2.6 3.1 2 1 1 3 3 2 0 Syntaxin 6, N-terminal Filo_VP35 PF02097.10 KFM05572.1 - 0.63 9.1 5.8 0.33 10.0 0.5 2.1 1 1 1 2 2 2 0 Filoviridae VP35 HAUS6_N PF14661.1 KFM05572.1 - 0.74 9.1 6.3 1.1 8.5 0.3 2.4 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF342 PF03961.8 KFM05572.1 - 0.75 8.1 14.4 0.08 11.3 5.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) FlaC_arch PF05377.6 KFM05572.1 - 0.76 9.7 16.4 1.3 8.9 2.2 4.1 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) ISG65-75 PF11727.3 KFM05572.1 - 0.84 8.6 11.0 0.028 13.4 2.0 2.1 2 0 0 2 2 2 0 Invariant surface glycoprotein Phage_GPO PF05929.6 KFM05572.1 - 0.95 8.6 9.2 0.91 8.7 2.9 2.6 1 1 2 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF745 PF05335.8 KFM05572.1 - 1.1 8.6 6.7 2.9 7.3 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) MRC1 PF09444.5 KFM05572.1 - 1.3 9.3 9.2 3.1 8.1 6.4 1.7 1 0 0 1 1 1 0 MRC1-like domain COG5 PF10392.4 KFM05572.1 - 1.4 8.8 9.1 2.2 8.2 0.5 2.7 2 1 0 2 2 2 0 Golgi transport complex subunit 5 CorA PF01544.13 KFM05572.1 - 2.3 7.1 10.5 0.55 9.2 0.9 2.8 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF883 PF05957.8 KFM05572.1 - 3.6 8.0 8.2 4.2 7.8 0.8 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF4404 PF14357.1 KFM05572.1 - 3.7 8.0 9.6 2.6 8.5 2.1 3.5 1 1 4 5 5 4 0 Domain of unknown function (DUF4404) Ead_Ea22 PF13935.1 KFM05572.1 - 3.9 7.7 12.5 2.8 8.2 3.4 2.6 2 2 0 2 2 2 0 Ead/Ea22-like protein Dna2 PF08696.6 KFM05572.1 - 4 6.7 10.1 1.3 8.2 0.9 2.5 1 1 0 2 2 2 0 DNA replication factor Dna2 DUF2203 PF09969.4 KFM05572.1 - 4.7 7.4 11.2 15 5.7 2.9 3.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) COG2 PF06148.6 KFM05572.1 - 5.1 6.9 13.4 15 5.4 3.9 3.5 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 UBN2 PF14223.1 KFM05572.1 - 5.2 6.8 12.3 0.53 10.0 1.6 2.9 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type APG6 PF04111.7 KFM05572.1 - 5.4 5.9 15.3 0.4 9.6 6.3 1.8 2 0 0 2 2 2 0 Autophagy protein Apg6 TBPIP PF07106.8 KFM05572.1 - 6.5 6.2 17.1 0.28 10.7 4.3 2.5 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Erp_C PF06780.6 KFM05572.1 - 7.6 6.3 13.6 3 7.6 6.1 2.5 2 2 0 2 2 1 0 Erp protein C-terminus YtxH PF12732.2 KFM05572.1 - 8.9 6.7 10.3 50 4.3 5.3 3.3 1 1 1 2 2 2 0 YtxH-like protein B9-C2 PF07162.6 KFM05573.1 - 3.9e-56 189.4 0.1 6.3e-56 188.7 0.0 1.3 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein BNIP3 PF06553.7 KFM05574.1 - 1.1 8.5 9.9 0.72 9.1 6.0 1.4 1 1 0 1 1 1 0 BNIP3 WD40 PF00400.27 KFM05575.1 - 3.9e-28 96.2 14.1 8.9e-08 31.7 0.2 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat BBS2_Mid PF14783.1 KFM05575.1 - 0.026 14.2 0.0 15 5.3 0.0 3.2 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Polysacc_deac_1 PF01522.16 KFM05575.1 - 0.028 14.0 0.0 5.6 6.6 0.0 2.7 2 1 0 2 2 2 0 Polysaccharide deacetylase eIF2A PF08662.6 KFM05575.1 - 0.045 13.4 0.1 0.58 9.8 0.0 2.7 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A SRCR PF00530.13 KFM05576.1 - 2.7e-35 120.6 10.8 3e-35 120.5 7.5 1.0 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 KFM05576.1 - 6e-05 23.2 2.1 6e-05 23.2 0.9 1.4 1 1 0 1 1 1 1 Scavenger receptor cysteine-rich domain Bromodomain PF00439.20 KFM05577.1 - 4.9e-22 77.6 0.1 1.1e-21 76.5 0.1 1.7 1 0 0 1 1 1 1 Bromodomain WAC_Acf1_DNA_bd PF10537.4 KFM05577.1 - 1.7e-21 76.2 0.5 1.7e-21 76.2 0.3 2.4 2 0 0 2 2 1 1 ATP-utilising chromatin assembly and remodelling N-terminal PHD PF00628.24 KFM05577.1 - 2e-13 49.7 6.1 6.1e-13 48.2 4.2 1.9 1 0 0 1 1 1 1 PHD-finger WHIM2 PF15613.1 KFM05577.1 - 6.3e-08 32.2 0.3 1.5e-07 31.0 0.2 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM1 PF15612.1 KFM05577.1 - 4.3e-06 26.3 0.1 1.8e-05 24.4 0.0 2.1 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM3 PF15614.1 KFM05577.1 - 6.8e-05 22.5 2.2 0.00028 20.5 0.1 2.8 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 3 Prok-RING_1 PF14446.1 KFM05577.1 - 0.00059 19.5 1.4 0.00059 19.5 1.0 2.1 2 0 0 2 2 1 1 Prokaryotic RING finger family 1 PHD_2 PF13831.1 KFM05577.1 - 0.0039 16.4 0.5 0.01 15.1 0.4 1.8 1 0 0 1 1 1 1 PHD-finger zf-RING_2 PF13639.1 KFM05577.1 - 0.0049 16.6 5.2 0.012 15.3 3.6 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KFM05577.1 - 0.018 15.1 4.5 0.056 13.5 3.1 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger zf-HC5HC2H PF13771.1 KFM05577.1 - 0.018 15.1 3.2 0.077 13.1 2.3 2.1 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-Apc11 PF12861.2 KFM05577.1 - 0.024 14.4 1.9 0.062 13.1 1.3 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Tnp_zf-ribbon_2 PF13842.1 KFM05577.1 - 0.17 12.2 3.6 0.95 9.9 2.5 2.4 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon zf-RING_5 PF14634.1 KFM05577.1 - 1.3 8.7 5.0 3.6 7.3 3.5 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-UDP PF14569.1 KFM05577.1 - 1.5 8.5 8.0 1.1 9.0 2.9 2.5 2 0 0 2 2 2 0 Zinc-binding RING-finger Frizzled PF01534.12 KFM05578.1 - 2.8e-141 470.0 18.5 3.5e-141 469.7 12.8 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.17 KFM05578.1 - 2.1e-34 118.3 4.3 4.2e-34 117.3 3.0 1.6 1 0 0 1 1 1 1 Fz domain Dicty_CAR PF05462.6 KFM05578.1 - 1e-05 24.5 7.0 1.8e-05 23.8 4.8 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor zf-DHHC PF01529.15 KFM05578.1 - 0.092 12.1 0.1 0.092 12.1 0.0 2.9 2 1 1 3 3 3 0 DHHC palmitoyltransferase FKBP_C PF00254.23 KFM05579.1 - 6.9e-15 54.8 0.0 2.5e-14 53.0 0.0 1.9 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_11 PF13414.1 KFM05579.1 - 3.5e-14 52.1 8.7 1.4e-08 34.2 0.6 2.2 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 KFM05579.1 - 3.6e-11 42.0 6.8 0.00037 20.1 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFM05579.1 - 3.8e-10 39.5 8.1 3.2e-06 26.9 1.0 2.9 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KFM05579.1 - 6.1e-06 25.6 4.8 0.015 14.8 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 KFM05579.1 - 1.1e-05 25.4 5.3 4.6e-05 23.4 2.8 2.1 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 KFM05579.1 - 0.00017 21.0 0.3 0.0021 17.7 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFM05579.1 - 0.00076 19.9 2.7 0.018 15.6 0.7 2.6 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFM05579.1 - 0.0012 19.1 0.5 0.0043 17.3 0.3 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 KFM05579.1 - 0.0017 18.2 5.0 0.0086 15.9 0.3 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFM05579.1 - 0.0032 17.1 1.4 2.2 8.3 0.2 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KFM05579.1 - 0.0033 17.2 1.6 0.66 9.8 0.0 2.4 1 1 1 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat Couple_hipA PF13657.1 KFM05579.1 - 0.029 14.6 0.0 0.058 13.7 0.0 1.5 1 1 0 1 1 1 0 HipA N-terminal domain TPR_16 PF13432.1 KFM05579.1 - 0.029 15.0 6.4 0.47 11.2 1.2 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 KFM05579.1 - 0.036 14.2 0.3 4.2 7.8 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Nol1_Nop2_Fmu PF01189.12 KFM05580.1 - 8.6e-28 97.5 0.0 1.4e-27 96.8 0.0 1.3 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 KFM05580.1 - 0.0021 17.6 0.0 0.0048 16.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 KFM05580.1 - 0.0056 16.6 0.0 0.0087 16.0 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 KFM05580.1 - 0.014 15.3 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ANTH PF07651.11 KFM05581.1 - 1.1e-72 244.0 7.0 2.7e-71 239.5 0.1 2.4 2 0 0 2 2 2 2 ANTH domain I_LWEQ PF01608.12 KFM05581.1 - 5.1e-58 195.3 8.5 5.1e-58 195.3 5.9 3.3 3 1 1 4 4 4 1 I/LWEQ domain ENTH PF01417.15 KFM05581.1 - 0.0073 16.1 0.0 0.025 14.4 0.0 1.9 1 0 0 1 1 1 1 ENTH domain Img2 PF05046.9 KFM05581.1 - 2.1 8.6 5.0 2 8.7 0.2 2.9 3 1 0 3 3 3 0 Mitochondrial large subunit ribosomal protein (Img2) IL8 PF00048.15 KFM05582.1 - 3.3e-22 78.2 0.2 4.3e-22 77.8 0.1 1.2 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like IL8 PF00048.15 KFM05583.1 - 2.8e-22 78.4 0.4 3.5e-22 78.1 0.2 1.2 1 1 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like IL8 PF00048.15 KFM05584.1 - 1.5e-22 79.3 0.4 1.6e-22 79.2 0.3 1.0 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like An_peroxidase PF03098.10 KFM05585.1 - 5e-175 582.8 0.0 5.8e-175 582.6 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase Acyltransferase PF01553.16 KFM05586.1 - 2.7e-36 123.9 0.1 4.4e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Spt4 PF06093.8 KFM05587.1 - 1.2e-26 92.3 0.1 1.4e-26 92.1 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger zf-RING_2 PF13639.1 KFM05588.1 - 6.9e-15 54.6 9.1 6.9e-15 54.6 6.3 2.7 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 KFM05588.1 - 4.2e-08 33.1 8.9 4.2e-08 33.1 6.2 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KFM05588.1 - 2.6e-07 30.1 7.7 2.6e-07 30.1 5.4 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM05588.1 - 2.4e-06 27.4 7.3 2.4e-06 27.4 5.1 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM05588.1 - 4.7e-05 23.0 6.5 4.7e-05 23.0 4.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFM05588.1 - 0.00064 19.3 4.2 0.00064 19.3 2.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KFM05588.1 - 0.063 13.2 4.4 0.19 11.7 3.0 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Apc11 PF12861.2 KFM05588.1 - 0.12 12.2 7.5 0.55 10.0 5.2 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF3827 PF12877.2 KFM05588.1 - 0.28 9.2 0.5 0.42 8.6 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) PHD PF00628.24 KFM05588.1 - 1.3 8.7 12.5 1.3 8.7 4.7 2.6 2 0 0 2 2 2 0 PHD-finger HSF_DNA-bind PF00447.12 KFM05589.1 - 2.3e-10 40.5 0.0 4e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Myotub-related PF06602.9 KFM05590.1 - 1.2e-144 481.4 0.0 1.5e-144 481.1 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.22 KFM05590.1 - 0.0012 18.2 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFM05590.1 - 0.0034 16.9 0.0 0.012 15.1 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFM05590.1 - 0.0072 16.5 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Peptidase_C14 PF00656.17 KFM05591.1 - 1.6e-40 139.4 0.0 2e-40 139.0 0.0 1.1 1 0 0 1 1 1 1 Caspase domain CARD PF00619.16 KFM05591.1 - 3.2e-18 65.3 0.1 1.1e-17 63.6 0.1 1.9 2 0 0 2 2 2 1 Caspase recruitment domain Abhydrolase_6 PF12697.2 KFM05592.1 - 1.8e-09 37.7 0.0 2.2e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFM05592.1 - 1.2e-05 24.9 0.0 1.9e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2048 PF09752.4 KFM05592.1 - 0.004 16.0 0.0 0.0043 15.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) Pkinase PF00069.20 KFM05593.1 - 1.5e-38 132.4 0.6 2.4e-37 128.5 0.4 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM05593.1 - 1.1e-36 126.1 0.2 6e-35 120.5 0.1 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase LIM PF00412.17 KFM05593.1 - 1.5e-29 101.8 21.3 3.6e-17 62.1 6.5 2.5 2 0 0 2 2 2 2 LIM domain PDZ PF00595.19 KFM05593.1 - 1e-09 38.4 0.0 2.5e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Kdo PF06293.9 KFM05593.1 - 0.00048 19.2 1.2 0.0015 17.6 0.2 2.0 1 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFM05593.1 - 0.0014 18.4 0.0 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KFM05593.1 - 0.0017 17.7 0.1 0.0032 16.8 0.1 1.3 1 0 0 1 1 1 1 RIO1 family PDZ_2 PF13180.1 KFM05593.1 - 0.02 14.7 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Kinase-like PF14531.1 KFM05593.1 - 0.1 11.5 0.0 1.7 7.5 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Septin PF00735.13 KFM05594.1 - 1.7e-124 414.4 0.2 1.9e-124 414.2 0.1 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KFM05594.1 - 2.1e-06 27.6 0.0 5e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFM05594.1 - 2.5e-05 23.7 0.0 0.0098 15.3 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KFM05594.1 - 4.2e-05 22.7 0.0 9.6e-05 21.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 KFM05594.1 - 0.0025 16.9 0.2 0.0087 15.1 0.0 2.0 3 0 0 3 3 3 1 AIG1 family Dynamin_N PF00350.18 KFM05594.1 - 0.009 15.8 1.7 0.24 11.2 0.0 2.7 1 1 1 2 2 2 1 Dynamin family Ras PF00071.17 KFM05594.1 - 0.021 14.1 0.0 0.063 12.6 0.0 1.8 1 0 0 1 1 1 0 Ras family AAA_22 PF13401.1 KFM05594.1 - 0.026 14.6 0.1 0.34 11.0 0.0 2.5 1 1 2 3 3 3 0 AAA domain AAA_10 PF12846.2 KFM05594.1 - 0.066 12.6 0.0 0.094 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain ABC_tran PF00005.22 KFM05594.1 - 0.085 13.1 0.1 0.14 12.4 0.0 1.5 1 1 0 1 1 1 0 ABC transporter Miro PF08477.8 KFM05594.1 - 0.14 12.6 0.2 0.95 9.9 0.0 2.2 2 1 1 3 3 3 0 Miro-like protein SBDS_C PF09377.5 KFM05595.1 - 1.5e-42 144.1 1.0 1.9e-42 143.9 0.7 1.1 1 0 0 1 1 1 1 SBDS protein C-terminal domain Dehydratase_SU PF02287.10 KFM05595.1 - 0.034 13.8 0.1 0.046 13.4 0.1 1.3 1 0 0 1 1 1 0 Dehydratase small subunit DUF2407 PF10302.4 KFM05595.1 - 0.059 13.5 0.7 0.11 12.7 0.5 1.5 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2356 PF10189.4 KFM05595.1 - 0.12 11.3 0.3 0.16 10.9 0.2 1.2 1 0 0 1 1 1 0 Conserved protein (DUF2356) Radical_SAM PF04055.16 KFM05596.1 - 6e-33 114.3 0.0 1.4e-32 113.1 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.7 KFM05596.1 - 5.4e-26 90.4 0.1 2.5e-25 88.3 0.0 2.3 2 0 0 2 2 2 1 Wyosine base formation Flavodoxin_1 PF00258.20 KFM05596.1 - 1.2e-22 80.4 0.0 2.4e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_NdrI PF07972.6 KFM05596.1 - 0.0064 16.3 0.0 0.022 14.6 0.0 2.0 2 0 0 2 2 2 1 NrdI Flavodoxin like EF-hand_1 PF00036.27 KFM05597.1 - 9.9e-18 62.0 6.6 8.2e-09 34.1 0.0 4.0 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.1 KFM05597.1 - 1.7e-16 60.1 1.9 1e-13 51.1 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KFM05597.1 - 4.7e-15 54.0 2.4 3.4e-08 32.6 0.0 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 KFM05597.1 - 1.9e-13 49.7 8.5 1.1e-10 40.9 0.2 4.1 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 KFM05597.1 - 4.5e-13 47.8 9.1 6.9e-06 25.1 0.0 4.1 4 0 0 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.4 KFM05597.1 - 0.0023 17.9 0.3 0.0085 16.1 0.0 2.0 2 1 1 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFM05597.1 - 0.0064 16.2 0.1 0.017 14.8 0.1 1.8 1 1 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KFM05597.1 - 0.0076 16.1 0.0 0.02 14.7 0.0 1.7 2 0 0 2 2 2 1 EF-hand domain EFhand_Ca_insen PF08726.5 KFM05597.1 - 0.041 13.8 0.2 0.24 11.4 0.0 2.3 2 1 0 2 2 2 0 Ca2+ insensitive EF hand Glycos_transf_2 PF00535.21 KFM05598.1 - 7.7e-27 94.0 0.0 1.4e-26 93.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 KFM05598.1 - 6.8e-18 64.8 0.1 1.1e-17 64.1 0.1 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.1 KFM05598.1 - 3.3e-07 30.3 0.0 0.00025 20.9 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 KFM05598.1 - 2.9e-05 23.2 0.0 4.4e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 KFM05598.1 - 0.00066 19.0 0.0 0.0016 17.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase RicinB_lectin_2 PF14200.1 KFM05598.1 - 0.046 14.0 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like Auts2 PF15336.1 KFM05599.1 - 2.1e-107 357.9 17.7 2.1e-107 357.9 12.3 4.6 3 2 0 3 3 3 1 Autism susceptibility gene 2 protein ACT_7 PF13840.1 KFM05600.1 - 3.3e-35 119.4 0.0 9e-20 69.9 0.0 2.3 2 0 0 2 2 2 2 ACT domain RCC1 PF00415.13 KFM05601.1 - 5e-60 199.5 14.9 1.2e-10 41.3 0.1 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KFM05601.1 - 2.6e-26 90.5 35.5 2.4e-07 30.1 0.2 7.7 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat GTF2I PF02946.9 KFM05602.1 - 2e-189 613.8 16.1 1.8e-31 107.7 0.0 6.2 6 0 0 6 6 6 6 GTF2I-like repeat Herpes_IE68 PF02479.11 KFM05602.1 - 0.017 14.2 0.5 15 4.7 0.0 4.5 5 0 0 5 5 5 0 Herpesvirus immediate early protein DUF1115 PF06544.7 KFM05602.1 - 0.26 10.9 1.6 17 5.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1115) GTF2I PF02946.9 KFM05603.1 - 8e-158 512.6 10.7 1.7e-31 107.8 0.0 5.4 5 0 0 5 5 5 5 GTF2I-like repeat DUSP PF06337.7 KFM05603.1 - 0.11 12.9 0.0 44 4.5 0.0 3.3 3 0 0 3 3 3 0 DUSP domain SR-25 PF10500.4 KFM05603.1 - 1.7 8.0 20.0 0.034 13.6 8.8 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CAP_GLY PF01302.20 KFM05604.1 - 3.8e-47 157.8 4.8 7.5e-24 83.2 0.2 2.3 2 0 0 2 2 2 2 CAP-Gly domain Rep_fac_C PF08542.6 KFM05605.1 - 2.9e-22 78.4 0.4 1.3e-21 76.3 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.24 KFM05605.1 - 2.5e-13 50.3 0.1 4.2e-13 49.6 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KFM05605.1 - 7.9e-12 45.1 0.0 1.7e-10 40.8 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 KFM05605.1 - 4.5e-07 29.8 0.0 7.6e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFM05605.1 - 2.5e-06 27.5 0.0 0.00016 21.7 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KFM05605.1 - 3.1e-06 27.3 0.3 0.00091 19.3 0.2 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFM05605.1 - 7e-06 25.7 0.0 1.6e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 KFM05605.1 - 3.9e-05 23.2 0.0 7.3e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.16 KFM05605.1 - 8.4e-05 21.8 0.0 0.0011 18.1 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 KFM05605.1 - 0.00012 21.6 0.1 0.1 12.0 0.0 2.6 1 1 0 2 2 2 2 AAA-like domain Rad17 PF03215.10 KFM05605.1 - 0.00026 19.8 0.0 0.21 10.2 0.0 2.3 1 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_11 PF13086.1 KFM05605.1 - 0.0004 20.0 0.0 0.00055 19.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 KFM05605.1 - 0.00046 19.7 0.9 0.089 12.2 0.0 2.9 1 1 0 3 3 3 1 DEAD/DEAH box helicase AAA_18 PF13238.1 KFM05605.1 - 0.0012 19.1 0.0 0.003 17.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain MipZ PF09140.6 KFM05605.1 - 0.0013 17.8 0.1 0.0017 17.5 0.0 1.1 1 0 0 1 1 1 1 ATPase MipZ RuvB_N PF05496.7 KFM05605.1 - 0.0014 17.7 0.0 0.0033 16.5 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 KFM05605.1 - 0.0018 17.7 0.4 0.007 15.7 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFM05605.1 - 0.0031 17.2 0.0 0.0075 15.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 KFM05605.1 - 0.0038 16.7 0.0 0.0075 15.7 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family ABC_tran PF00005.22 KFM05605.1 - 0.011 15.9 0.0 0.034 14.4 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 KFM05605.1 - 0.013 15.4 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 KFM05605.1 - 0.02 13.6 0.1 0.054 12.2 0.1 1.7 1 1 1 2 2 2 0 ArgK protein NTPase_1 PF03266.10 KFM05605.1 - 0.021 14.5 0.2 0.16 11.6 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.1 KFM05605.1 - 0.022 14.3 0.4 0.2 11.2 0.3 2.3 1 1 0 1 1 1 0 AAA domain SNF2_N PF00176.18 KFM05605.1 - 0.027 13.2 0.1 5.9 5.5 0.0 2.3 1 1 1 2 2 2 0 SNF2 family N-terminal domain DUF2075 PF09848.4 KFM05605.1 - 0.03 13.3 0.4 0.3 10.0 0.3 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 KFM05605.1 - 0.034 14.9 1.2 0.087 13.6 0.7 1.9 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KFM05605.1 - 0.038 13.3 0.0 0.074 12.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.1 KFM05605.1 - 0.047 13.2 0.0 0.077 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KFM05605.1 - 0.064 13.4 0.0 0.21 11.7 0.0 2.0 1 1 0 1 1 1 0 RNA helicase T2SE PF00437.15 KFM05605.1 - 0.08 11.8 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.1 KFM05605.1 - 0.094 13.0 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF4597 PF15366.1 KFM05605.1 - 0.13 11.8 0.6 1.9 8.1 0.1 2.5 3 0 0 3 3 2 0 Domain of unknown function (DUF4597) RRM_1 PF00076.17 KFM05606.1 - 2e-13 49.7 0.0 3.1e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM05606.1 - 4.9e-10 39.2 0.0 7.3e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM05606.1 - 4.6e-07 29.5 0.0 6.7e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_pol_phi PF04931.8 KFM05607.1 - 2.4e-130 435.7 28.6 2.4e-130 435.7 19.8 2.0 2 0 0 2 2 2 1 DNA polymerase phi MFS_1 PF07690.11 KFM05608.1 - 6.1e-38 130.4 37.8 6.2e-38 130.3 20.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFM05608.1 - 1.9e-14 53.1 27.6 2.8e-14 52.5 19.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 KFM05608.1 - 4.5e-12 44.8 20.0 1.4e-06 26.6 0.1 4.1 2 2 2 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.1 KFM05608.1 - 1.1e-09 37.2 21.4 2.9e-06 25.9 4.1 2.6 1 1 1 2 2 2 2 MFS/sugar transport protein ATG22 PF11700.3 KFM05608.1 - 3.8e-05 22.3 8.5 3.8e-05 22.3 5.9 2.7 2 1 1 3 3 3 1 Vacuole effluxer Atg22 like Gemin6 PF06372.7 KFM05608.1 - 0.081 12.2 0.1 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Gemin6 protein UQ_con PF00179.21 KFM05609.1 - 4.7e-50 168.6 0.0 5.3e-50 168.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KFM05609.1 - 0.073 12.9 0.0 0.098 12.5 0.0 1.3 1 0 0 1 1 1 0 RWD domain Ank_2 PF12796.2 KFM05610.1 - 3.1e-107 351.1 27.6 7.1e-20 71.1 0.0 11.5 4 3 6 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.25 KFM05610.1 - 4.7e-102 329.0 41.0 5.7e-12 44.8 0.0 22.1 22 1 0 22 22 22 18 Ankyrin repeat Ank_5 PF13857.1 KFM05610.1 - 1.5e-72 238.0 32.8 3.3e-09 36.6 0.0 15.2 11 3 5 16 16 16 13 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFM05610.1 - 6.4e-72 236.7 29.3 1.5e-08 34.9 0.0 18.1 6 6 13 19 19 19 15 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM05610.1 - 1.3e-69 223.0 30.9 6e-05 22.8 0.0 20.8 22 0 0 22 22 22 15 Ankyrin repeat FYVE PF01363.16 KFM05610.1 - 2.1e-16 59.5 9.8 4.2e-16 58.5 6.8 1.5 1 0 0 1 1 1 1 FYVE zinc finger BTB PF00651.26 KFM05610.1 - 4.6e-16 58.7 0.1 1.8e-15 56.8 0.1 2.0 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.10 KFM05610.1 - 0.0063 16.3 1.7 0.015 15.1 0.3 2.3 2 0 0 2 2 2 1 BTB And C-terminal Kelch Glyoxalase_4 PF13669.1 KFM05610.1 - 0.13 12.3 0.1 5.8 6.9 0.0 3.2 3 0 0 3 3 3 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FYVE_2 PF02318.11 KFM05610.1 - 1.1 9.1 11.5 0.31 10.9 5.4 2.0 2 0 0 2 2 2 0 FYVE-type zinc finger P2X_receptor PF00864.14 KFM05611.1 - 1.6e-165 550.3 0.3 1.8e-165 550.1 0.2 1.0 1 0 0 1 1 1 1 ATP P2X receptor WAP PF00095.16 KFM05611.1 - 0.24 11.4 2.1 1.2 9.1 1.4 2.3 1 0 0 1 1 1 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' Pkinase PF00069.20 KFM05612.1 - 4.1e-66 222.7 0.0 6.3e-66 222.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM05612.1 - 1.4e-33 116.0 0.0 2.2e-31 108.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KFM05612.1 - 1.5e-08 33.9 0.0 2.4e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFM05612.1 - 0.17 11.6 0.3 0.66 9.6 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Mis12 PF05859.7 KFM05613.1 - 8.5e-45 152.1 3.3 1.4e-44 151.3 2.3 1.3 1 0 0 1 1 1 1 Mis12 protein DUF2018 PF09442.5 KFM05613.1 - 0.0012 19.3 0.2 0.0037 17.7 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF2018) APG17 PF04108.7 KFM05613.1 - 0.0067 15.2 5.9 0.0089 14.8 2.0 1.9 2 0 0 2 2 2 1 Autophagy protein Apg17 BBP1_C PF15272.1 KFM05613.1 - 0.068 12.7 0.2 0.068 12.7 0.1 2.1 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal DUF2573 PF10835.3 KFM05613.1 - 0.078 13.0 0.7 1.2 9.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2573) GreA_GreB_N PF03449.10 KFM05613.1 - 0.082 12.9 0.2 0.082 12.9 0.1 2.6 2 1 1 3 3 3 0 Transcription elongation factor, N-terminal DUF4296 PF14129.1 KFM05613.1 - 0.086 12.9 0.6 0.71 10.0 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4296) DUF4108 PF13390.1 KFM05613.1 - 0.11 12.2 2.1 0.087 12.5 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4108) DASH_Dad3 PF08656.5 KFM05613.1 - 0.14 11.8 2.8 1.1 8.9 0.2 2.4 2 0 0 2 2 2 0 DASH complex subunit Dad3 LLC1 PF14945.1 KFM05613.1 - 0.16 12.3 2.9 1.7 8.9 0.1 2.3 2 0 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Tho2 PF11262.3 KFM05613.1 - 0.18 10.8 3.5 0.075 12.0 0.4 1.7 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Lzipper-MIP1 PF14389.1 KFM05613.1 - 0.44 10.6 7.2 4.1 7.5 4.9 2.4 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 FlxA PF14282.1 KFM05613.1 - 0.55 10.1 8.2 0.41 10.6 2.3 2.1 2 0 0 2 2 2 0 FlxA-like protein Prefoldin_2 PF01920.15 KFM05613.1 - 1.1 9.0 10.8 5.4 6.8 3.1 2.5 2 0 0 2 2 2 0 Prefoldin subunit DUF4140 PF13600.1 KFM05613.1 - 1.1 9.7 4.2 0.7 10.3 1.0 2.0 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Acetyltransf_11 PF13720.1 KFM05613.1 - 1.1 9.4 3.6 18 5.6 0.6 2.4 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DUF2992 PF11208.3 KFM05613.1 - 1.3 8.9 6.5 0.4 10.5 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) OmpH PF03938.9 KFM05613.1 - 6.3 6.7 13.7 35 4.2 9.5 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF904 PF06005.7 KFM05613.1 - 7.7 6.8 10.9 44 4.4 6.8 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF904) DER1 PF04511.10 KFM05614.1 - 4.1e-61 205.9 11.7 4.6e-61 205.7 8.1 1.0 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.17 KFM05614.1 - 0.28 11.2 19.1 0.44 10.5 13.2 1.3 1 1 0 1 1 1 0 Rhomboid family DUF2304 PF10066.4 KFM05614.1 - 5.1 6.9 6.9 0.69 9.7 1.2 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2304) OB_NTP_bind PF07717.11 KFM05615.1 - 3.7e-23 81.5 0.0 7.2e-23 80.5 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KFM05615.1 - 5.1e-23 81.0 0.0 1e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KFM05615.1 - 1e-12 47.7 0.0 2.4e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFM05615.1 - 2.9e-06 26.8 1.1 1.6e-05 24.4 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KFM05615.1 - 0.042 13.9 0.1 0.15 12.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain MAM33 PF02330.11 KFM05616.1 - 2.4e-70 236.4 4.0 2.7e-70 236.3 2.8 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein DUF524 PF04411.7 KFM05616.1 - 0.022 14.5 0.1 0.062 13.1 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF524) RPA_interact_C PF14768.1 KFM05617.1 - 2.8e-18 66.0 3.3 5e-18 65.2 2.3 1.4 1 0 0 1 1 1 1 Replication protein A interacting C-terminal RPA_interact_M PF14767.1 KFM05617.1 - 4.7e-10 40.0 9.0 1.2e-09 38.8 6.2 1.6 1 1 0 1 1 1 1 Replication protein A interacting middle zf-RING_2 PF13639.1 KFM05617.1 - 0.29 10.9 0.0 0.29 10.9 0.0 2.3 3 1 0 3 3 3 0 Ring finger domain Nup88 PF10168.4 KFM05618.1 - 0 1128.8 0.7 0 1128.7 0.5 1.0 1 0 0 1 1 1 1 Nuclear pore component Syntaxin-6_N PF09177.6 KFM05618.1 - 0.021 15.2 2.6 0.021 15.2 1.8 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal KxDL PF10241.4 KFM05618.1 - 0.16 11.8 7.3 0.13 12.1 3.5 2.1 2 1 0 2 2 2 0 Uncharacterized conserved protein DUF342 PF03961.8 KFM05618.1 - 0.85 7.9 11.2 1.3 7.3 7.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) BLOC1_2 PF10046.4 KFM05618.1 - 0.96 9.6 10.8 8.9 6.5 1.2 3.3 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Nup54 PF13874.1 KFM05618.1 - 1.3 8.6 13.6 3.3 7.3 9.4 1.7 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 APG6 PF04111.7 KFM05618.1 - 1.9 7.4 16.4 2.9 6.8 11.4 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4208 PF13907.1 KFM05618.1 - 3.1 8.0 13.8 0.29 11.3 5.4 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4208) LMBR1 PF04791.11 KFM05618.1 - 3.4 6.1 4.9 5.1 5.5 3.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein IncA PF04156.9 KFM05618.1 - 4.9 6.6 20.6 6.4 6.3 13.0 2.1 1 1 0 1 1 1 0 IncA protein Latarcin PF10279.4 KFM05618.1 - 9.1 6.5 11.2 2.6 8.3 4.6 2.3 2 1 0 2 2 2 0 Latarcin precursor Fib_alpha PF08702.5 KFM05618.1 - 9.6 6.3 15.0 1 9.4 4.3 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Rabaptin PF03528.10 KFM05619.1 - 1.2e-78 259.8 33.3 2e-43 146.6 11.9 9.2 5 3 1 6 6 6 3 Rabaptin Rab5-bind PF09311.6 KFM05619.1 - 6.2e-45 153.3 39.1 6.2e-45 153.3 27.1 5.6 3 1 2 5 5 5 2 Rabaptin-like protein Ras PF00071.17 KFM05620.1 - 6.2e-07 28.9 0.0 7.7e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM05620.1 - 0.0076 16.7 0.0 0.011 16.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM05620.1 - 0.012 14.8 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family C2 PF00168.25 KFM05621.1 - 2.2e-06 27.4 0.0 3.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 C2 domain CUT PF02376.10 KFM05622.1 - 9.2e-32 108.7 0.4 1.6e-31 107.9 0.3 1.3 1 0 0 1 1 1 1 CUT domain Homeobox PF00046.24 KFM05622.1 - 2.5e-10 39.7 0.6 4.7e-10 38.9 0.4 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFM05622.1 - 0.0012 18.5 0.0 0.0034 17.0 0.0 1.8 1 0 0 1 1 1 1 Homeobox KN domain DUF4210 PF13915.1 KFM05623.1 - 3.8e-20 71.9 0.1 1.1e-19 70.4 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 KFM05623.1 - 1.2e-19 69.9 0.4 2.9e-19 68.6 0.3 1.7 1 0 0 1 1 1 1 Chromosome segregation during meiosis Endosulfine PF04667.12 KFM05624.1 - 5e-15 55.2 0.9 5.8e-15 55.0 0.6 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Myosin_head PF00063.16 KFM05625.1 - 5.9e-266 883.9 2.7 6.8e-266 883.7 1.9 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.22 KFM05625.1 - 2e-17 61.1 32.7 6.9e-05 22.1 2.7 4.7 4 0 0 4 4 4 4 IQ calmodulin-binding motif AAA_22 PF13401.1 KFM05625.1 - 0.0015 18.7 0.1 0.0085 16.2 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KFM05625.1 - 0.018 15.0 0.0 0.21 11.5 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain T2SE PF00437.15 KFM05625.1 - 0.085 11.7 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 KFM05625.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Myosin_head PF00063.16 KFM05626.1 - 2.1e-252 839.1 10.2 2.5e-252 838.9 7.1 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.22 KFM05626.1 - 1.9e-18 64.2 27.1 4.5e-06 25.8 0.6 4.8 4 0 0 4 4 4 4 IQ calmodulin-binding motif AAA_22 PF13401.1 KFM05626.1 - 0.0015 18.6 0.0 0.0056 16.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain Myosin_N PF02736.14 KFM05626.1 - 0.027 14.1 0.0 0.055 13.1 0.0 1.5 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain AAA_16 PF13191.1 KFM05626.1 - 0.034 14.1 0.0 0.092 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain DUF3456 PF11938.3 KFM05626.1 - 0.056 13.4 1.1 11 5.9 0.2 2.6 2 0 0 2 2 2 0 TLR4 regulator and MIR-interacting MSAP T2SE PF00437.15 KFM05626.1 - 0.078 11.8 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DIL PF01843.14 KFM05627.1 - 1.7e-34 117.8 1.7 1.7e-34 117.8 1.2 2.8 3 0 0 3 3 3 1 DIL domain IQ PF00612.22 KFM05627.1 - 0.00015 21.1 2.6 0.00056 19.3 1.8 2.1 1 0 0 1 1 1 1 IQ calmodulin-binding motif WD40 PF00400.27 KFM05628.1 - 8.7e-40 133.2 14.3 6.4e-09 35.3 0.0 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat DLD PF14878.1 KFM05628.1 - 0.058 13.5 0.0 0.095 12.8 0.0 1.3 1 0 0 1 1 1 0 Death-like domain of SPT6 Pkinase PF00069.20 KFM05629.1 - 5.4e-64 215.8 0.0 8.4e-64 215.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM05629.1 - 1.2e-25 90.0 0.0 2.2e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFM05629.1 - 0.001 18.8 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family HPIP PF15226.1 KFM05629.1 - 0.01 15.8 0.1 0.029 14.4 0.0 1.7 1 0 0 1 1 1 0 HCF-1 beta-propeller-interacting protein family Kinase-like PF14531.1 KFM05629.1 - 0.048 12.6 0.1 0.25 10.2 0.0 2.2 2 1 0 2 2 2 0 Kinase-like Leo1 PF04004.8 KFM05630.1 - 6.4e-56 188.7 0.0 6.4e-56 188.7 0.0 3.6 2 1 0 2 2 2 1 Leo1-like protein Tropomodulin PF03250.9 KFM05631.1 - 7.4e-61 203.9 5.3 1.6e-60 202.8 3.7 1.6 1 0 0 1 1 1 1 Tropomodulin LRR_6 PF13516.1 KFM05631.1 - 0.059 13.4 1.4 0.49 10.6 0.1 3.0 2 0 0 2 2 2 0 Leucine Rich repeat HTH_6 PF01418.12 KFM05631.1 - 0.12 12.0 0.5 0.39 10.4 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family LRR_4 PF12799.2 KFM05631.1 - 5.5 6.7 8.9 3.8 7.2 2.0 3.2 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) Tropomodulin PF03250.9 KFM05632.1 - 6.9e-44 148.9 5.5 1.5e-43 147.7 1.4 2.6 3 0 0 3 3 3 1 Tropomodulin LRR_6 PF13516.1 KFM05632.1 - 0.057 13.5 0.9 0.46 10.7 0.1 2.9 3 0 0 3 3 3 0 Leucine Rich repeat Hormone_2 PF00123.15 KFM05633.1 - 0.78 9.6 0.1 0.78 9.6 0.0 2.4 3 0 0 3 3 3 0 Peptide hormone SGIII PF15467.1 KFM05634.1 - 4.1e-228 757.9 32.9 4.7e-228 757.7 22.8 1.0 1 0 0 1 1 1 1 Secretogranin-3 DUF2680 PF10925.3 KFM05634.1 - 9.1e-08 31.8 4.2 0.16 11.8 0.1 4.6 3 1 1 4 4 4 3 Protein of unknown function (DUF2680) Phage_XkdX PF09693.5 KFM05634.1 - 0.092 12.2 0.1 27 4.3 0.0 3.3 3 0 0 3 3 3 0 Phage uncharacterised protein (Phage_XkdX) DUF1227 PF06777.6 KFM05634.1 - 0.1 12.2 3.9 1.9 8.2 0.0 4.0 3 1 0 4 4 4 0 Protein of unknown function (DUF1227) Plasmid_stabil PF05016.9 KFM05634.1 - 0.16 12.4 1.8 1.1 9.6 0.1 3.0 2 2 0 2 2 2 0 Plasmid stabilisation system protein DUF2201_N PF13203.1 KFM05634.1 - 0.24 10.5 9.3 0.029 13.5 2.7 2.0 2 0 0 2 2 2 0 Putative metallopeptidase domain DUF758 PF05527.6 KFM05635.1 - 7.6e-98 325.5 6.7 8.4e-98 325.4 4.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF758) Seadorna_VP6 PF07407.6 KFM05635.1 - 0.018 13.8 0.6 0.018 13.8 0.4 1.5 1 1 1 2 2 2 0 Seadornavirus VP6 protein DUF2408 PF10303.4 KFM05635.1 - 0.025 14.7 2.6 0.053 13.6 1.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) PFO_beta_C PF12367.3 KFM05635.1 - 0.064 13.1 0.2 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal Rsd_AlgQ PF04353.8 KFM05635.1 - 0.076 12.7 4.2 0.38 10.4 1.9 2.1 1 1 1 2 2 2 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ DALR_1 PF05746.10 KFM05635.1 - 0.13 12.2 2.6 0.17 11.8 1.2 1.6 1 1 0 1 1 1 0 DALR anticodon binding domain DUF939_C PF11728.3 KFM05635.1 - 0.2 11.4 6.5 0.86 9.4 2.5 2.2 1 1 2 3 3 3 0 DUF939 C-terminal domain p450 PF00067.17 KFM05636.1 - 1.8e-104 349.8 0.4 2.1e-104 349.6 0.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 OLF PF02191.11 KFM05637.1 - 2.3e-64 217.0 1.9 2.7e-64 216.8 1.3 1.0 1 0 0 1 1 1 1 Olfactomedin-like domain Collagen PF01391.13 KFM05637.1 - 4e-16 58.3 66.8 1e+02 2.5 46.3 3.0 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) Sema PF01403.14 KFM05638.1 - 5.5e-136 453.5 0.1 8.9e-136 452.8 0.1 1.2 1 0 0 1 1 1 1 Sema domain PSI PF01437.20 KFM05638.1 - 3e-07 30.4 2.4 7.3e-07 29.2 1.7 1.6 1 0 0 1 1 1 1 Plexin repeat PP1_bind PF15276.1 KFM05638.1 - 0.22 11.5 5.9 2.4 8.2 0.3 3.1 2 0 0 2 2 2 0 Protein phosphatase 1 binding Na_Ca_ex PF01699.19 KFM05639.1 - 1e-49 167.7 30.6 9.3e-26 90.1 8.9 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF1761 PF08570.5 KFM05639.1 - 0.2 11.6 11.0 0.7 9.9 0.2 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1761) RRM_1 PF00076.17 KFM05640.1 - 3.5e-57 189.9 0.6 1.9e-19 69.0 0.0 3.5 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM05640.1 - 1.6e-36 124.1 0.5 6.2e-12 45.3 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM05640.1 - 6.3e-22 77.1 0.6 1.7e-06 27.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFM05640.1 - 5.9e-08 32.5 0.7 0.002 17.9 0.0 3.2 3 0 0 3 3 3 2 RNA binding motif Limkain-b1 PF11608.3 KFM05640.1 - 4.2e-07 29.6 0.1 0.005 16.5 0.0 2.9 2 1 0 2 2 2 2 Limkain b1 DUF3932 PF13068.1 KFM05640.1 - 0.019 15.0 0.0 2.6 8.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3932) Cortexin PF11057.3 KFM05641.1 - 5.1e-34 115.7 0.0 5.5e-34 115.6 0.0 1.0 1 0 0 1 1 1 1 Cortexin of kidney AA_permease PF00324.16 KFM05642.1 - 4.1e-150 500.2 38.9 5e-150 499.9 27.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_N PF08403.5 KFM05642.1 - 6e-25 86.3 0.1 1.6e-24 84.9 0.0 1.8 1 0 0 1 1 1 1 Amino acid permease N-terminal AA_permease_2 PF13520.1 KFM05642.1 - 9.5e-22 77.1 43.0 1.5e-21 76.4 29.8 1.2 1 0 0 1 1 1 1 Amino acid permease DUF1682 PF07946.9 KFM05642.1 - 0.026 13.3 0.4 0.048 12.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) dUTPase PF00692.14 KFM05643.1 - 2.1e-21 75.7 0.0 2.2e-21 75.6 0.0 1.0 1 0 0 1 1 1 1 dUTPase PID PF00640.18 KFM05644.1 - 3.4e-44 150.2 0.0 6.8e-44 149.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SH2 PF00017.19 KFM05644.1 - 2.9e-16 59.0 0.0 2.1e-15 56.2 0.0 2.3 2 0 0 2 2 2 1 SH2 domain Ribosomal_L7Ae PF01248.21 KFM05645.1 - 2.6e-22 78.1 0.1 8.1e-22 76.5 0.0 1.9 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RrnaAD PF00398.15 KFM05645.1 - 0.0083 15.1 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCI PF01399.22 KFM05646.1 - 8.9e-26 90.2 1.7 8.9e-26 90.2 1.2 2.7 3 0 0 3 3 3 1 PCI domain PCI_Csn8 PF10075.4 KFM05646.1 - 1.3e-22 80.1 0.1 3.9e-22 78.5 0.1 1.8 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_2 PF07719.12 KFM05646.1 - 0.28 11.1 2.6 18 5.5 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFM05646.1 - 0.41 10.3 3.7 6 6.6 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat GalKase_gal_bdg PF10509.4 KFM05647.1 - 1.6e-23 81.7 0.0 3.4e-23 80.6 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 KFM05647.1 - 1.4e-13 50.6 0.4 4.2e-13 49.1 0.3 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KFM05647.1 - 4.3e-12 46.0 0.0 1.2e-11 44.6 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal FGF PF00167.13 KFM05648.1 - 9.5e-45 151.3 2.4 1.3e-44 150.8 1.7 1.1 1 0 0 1 1 1 1 Fibroblast growth factor DTW PF03942.10 KFM05649.1 - 1.2e-52 178.0 0.0 1.6e-52 177.7 0.0 1.1 1 0 0 1 1 1 1 DTW domain B12D PF06522.6 KFM05650.1 - 9.1e-19 66.9 0.0 1e-18 66.7 0.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Cation_efflux PF01545.16 KFM05651.1 - 7.1e-66 222.1 12.6 8.3e-66 221.9 8.7 1.0 1 0 0 1 1 1 1 Cation efflux family DUF3681 PF12442.3 KFM05651.1 - 0.043 13.9 0.5 0.1 12.7 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3681) DUF1282 PF06930.7 KFM05651.1 - 0.26 10.9 10.5 1.3 8.6 4.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1282) DUF3112 PF11309.3 KFM05651.1 - 1.4 8.7 6.4 4.4 7.0 4.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3112) Snapin_Pallidin PF14712.1 KFM05652.1 - 3.2e-21 75.4 3.7 4e-21 75.1 2.6 1.0 1 0 0 1 1 1 1 Snapin/Pallidin ALS2CR8 PF15299.1 KFM05652.1 - 0.08 12.5 0.1 0.093 12.3 0.1 1.1 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 Pyr_redox_2 PF07992.9 KFM05653.1 - 6.6e-10 39.2 0.0 2.8e-09 37.1 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFM05653.1 - 0.045 13.7 0.6 15 5.6 0.3 3.0 1 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase AAA_18 PF13238.1 KFM05654.1 - 1.3e-15 57.8 0.0 3.7e-15 56.3 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 KFM05654.1 - 2.1e-05 25.3 0.1 0.00035 21.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KFM05654.1 - 0.00071 19.4 0.0 0.0013 18.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KFM05654.1 - 0.052 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase MobB PF03205.9 KFM05654.1 - 0.053 13.2 0.5 2.1 8.0 0.0 2.7 3 1 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B PBD PF00786.23 KFM05655.1 - 2.9e-05 24.4 0.1 3.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 P21-Rho-binding domain Peptidase_A22B PF04258.8 KFM05656.1 - 5.7e-86 288.6 21.2 1e-85 287.8 14.7 1.3 1 0 0 1 1 1 1 Signal peptide peptidase PA PF02225.17 KFM05656.1 - 4e-16 58.5 0.0 6.8e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 PA domain Presenilin PF01080.12 KFM05656.1 - 0.00033 19.5 21.6 0.00098 18.0 2.1 2.1 2 0 0 2 2 2 2 Presenilin Tic20 PF09685.5 KFM05656.1 - 0.092 12.7 0.2 0.092 12.7 0.1 4.1 4 1 0 4 4 4 0 Tic20-like protein Tmemb_9 PF05434.6 KFM05656.1 - 2.8 7.6 11.1 3.6 7.3 0.0 3.2 3 0 0 3 3 3 0 TMEM9 UCH PF00443.24 KFM05657.1 - 2.1e-51 174.6 0.1 2.5e-51 174.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFM05657.1 - 2e-20 73.4 0.2 2.5e-20 73.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-ribbon_3 PF13248.1 KFM05657.1 - 0.096 11.9 0.5 8.7 5.7 0.0 2.6 2 0 0 2 2 2 0 zinc-ribbon domain UCH PF00443.24 KFM05658.1 - 7.1e-87 290.9 5.9 7.1e-87 290.9 4.1 2.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.6 KFM05658.1 - 3.2e-31 107.6 6.5 3.2e-31 107.6 4.5 2.8 2 1 0 2 2 2 1 USP8 dimerisation domain UCH_1 PF13423.1 KFM05658.1 - 8.1e-29 100.9 2.9 8.1e-29 100.9 2.0 2.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 KFM05658.1 - 8.5e-10 38.9 1.0 4.2e-09 36.7 0.0 2.8 3 0 0 3 3 3 1 Rhodanese-like domain Metallothio_Pro PF02069.11 KFM05658.1 - 0.084 12.7 0.6 0.35 10.7 0.4 2.0 2 0 0 2 2 2 0 Prokaryotic metallothionein SAPS PF04499.10 KFM05658.1 - 0.27 9.8 21.3 0.0071 15.0 6.4 2.3 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Ank_2 PF12796.2 KFM05659.1 - 4e-53 177.6 8.3 2.3e-22 79.1 0.4 3.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KFM05659.1 - 3.3e-37 124.4 0.8 1.2e-11 43.7 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.1 KFM05659.1 - 1.3e-27 93.0 0.5 4.1e-08 32.7 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 KFM05659.1 - 2e-27 94.5 1.0 4.4e-09 36.3 0.0 4.5 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFM05659.1 - 5.2e-24 84.1 0.3 2.3e-10 40.7 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Sec5 PF15469.1 KFM05659.1 - 0.017 14.8 2.9 0.033 13.9 2.0 1.4 1 0 0 1 1 1 0 Exocyst complex component Sec5 Topo-VIb_trans PF09239.6 KFM05659.1 - 1.5 8.3 5.0 31 4.0 0.0 2.9 2 1 0 2 2 2 0 Topoisomerase VI B subunit, transducer Pyridoxal_deC PF00282.14 KFM05660.1 - 5.8e-163 541.6 0.0 7.2e-163 541.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 KFM05660.1 - 0.00014 21.1 0.0 0.00025 20.3 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 KFM05660.1 - 0.073 12.0 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II AMP-binding PF00501.23 KFM05661.1 - 1.2e-44 152.3 0.0 1.7e-44 151.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFM05661.1 - 1.6e-06 28.9 0.0 3.1e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Acid_PPase PF12689.2 KFM05661.1 - 0.033 13.8 0.1 0.14 11.7 0.0 2.1 3 0 0 3 3 3 0 Acid Phosphatase Amidinotransf PF02274.12 KFM05662.1 - 4.6e-14 52.1 0.0 1.9e-08 33.7 0.0 2.2 2 0 0 2 2 2 2 Amidinotransferase PDEase_I PF00233.14 KFM05663.1 - 3.8e-64 216.6 0.7 7.3e-64 215.7 0.5 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Response_reg PF00072.19 KFM05663.1 - 6e-15 55.2 0.0 1.2e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 KFM05663.1 - 7.1e-13 48.8 0.0 2.2e-12 47.2 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 KFM05663.1 - 3.7e-12 46.0 0.0 1.2e-11 44.4 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 KFM05663.1 - 1.7e-05 24.8 0.0 5.2e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.1 KFM05663.1 - 0.00023 20.8 0.0 0.00078 19.2 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.6 KFM05663.1 - 0.00091 19.2 0.0 0.0019 18.2 0.0 1.6 1 0 0 1 1 1 1 PAS fold fn3 PF00041.16 KFM05664.1 - 1.8e-16 60.0 0.0 9.6e-11 41.6 0.0 2.7 3 0 0 3 3 3 2 Fibronectin type III domain SPRY PF00622.23 KFM05664.1 - 1.3e-13 51.1 0.0 2.9e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 SPRY domain PRY PF13765.1 KFM05664.1 - 0.0059 16.1 0.0 0.027 13.9 0.0 2.1 2 0 0 2 2 2 1 SPRY-associated domain Interfer-bind PF09294.5 KFM05664.1 - 0.042 13.8 0.4 1.9 8.5 0.2 2.6 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III DUF3552 PF12072.3 KFM05664.1 - 0.086 12.0 5.3 0.24 10.5 3.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) CorA PF01544.13 KFM05664.1 - 0.26 10.2 2.2 0.53 9.2 1.5 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein WH2 PF02205.15 KFM05665.1 - 0.00049 19.6 0.4 0.0025 17.3 0.1 2.2 2 0 0 2 2 2 1 WH2 motif PSI_PsaF PF02507.10 KFM05665.1 - 5.3 6.5 6.6 0.66 9.4 0.1 2.4 2 0 0 2 2 2 0 Photosystem I reaction centre subunit III WH1 PF00568.18 KFM05666.1 - 2.8e-36 123.5 0.4 6.5e-36 122.4 0.3 1.6 1 0 0 1 1 1 1 WH1 domain CALCOCO1 PF07888.6 KFM05666.1 - 2.7e-05 22.6 27.4 2.7e-05 22.6 19.0 1.6 1 1 1 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like Macoilin PF09726.4 KFM05666.1 - 7.8e-05 21.1 23.8 0.00011 20.7 16.5 1.2 1 0 0 1 1 1 1 Transmembrane protein DMPK_coil PF08826.5 KFM05666.1 - 8.2e-05 22.4 3.7 8.2e-05 22.4 2.6 3.8 2 1 1 3 3 3 1 DMPK coiled coil domain like GAS PF13851.1 KFM05666.1 - 0.0005 19.3 41.8 0.0029 16.8 13.7 3.4 1 1 2 3 3 3 2 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.3 KFM05666.1 - 0.0013 18.5 9.3 0.0013 18.5 6.4 3.8 2 1 2 4 4 3 1 TATA element modulatory factor 1 DNA binding DUF4201 PF13870.1 KFM05666.1 - 0.0024 17.3 6.9 0.0024 17.3 4.8 3.3 2 1 2 4 4 4 2 Domain of unknown function (DUF4201) Reo_sigmaC PF04582.7 KFM05666.1 - 0.0062 15.7 12.0 0.01 15.0 1.1 2.6 2 1 1 3 3 3 2 Reovirus sigma C capsid protein IncA PF04156.9 KFM05666.1 - 0.0091 15.6 21.6 0.0091 15.6 15.0 3.0 1 1 2 3 3 3 2 IncA protein Phage_GP20 PF06810.6 KFM05666.1 - 0.011 15.2 11.8 0.011 15.2 8.1 3.6 2 1 2 4 4 3 0 Phage minor structural protein GP20 bZIP_1 PF00170.16 KFM05666.1 - 0.023 14.6 4.3 0.023 14.6 3.0 5.7 2 1 4 6 6 5 0 bZIP transcription factor BLOC1_2 PF10046.4 KFM05666.1 - 0.023 14.8 1.9 0.023 14.8 1.3 3.6 2 1 2 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FUSC PF04632.7 KFM05666.1 - 0.088 11.2 4.1 0.13 10.6 2.8 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Laminin_II PF06009.7 KFM05666.1 - 0.12 12.1 23.4 0.059 13.1 4.5 3.0 2 1 1 3 3 3 0 Laminin Domain II Myosin_tail_1 PF01576.14 KFM05666.1 - 0.16 9.6 42.1 0.33 8.5 29.2 1.5 1 1 0 1 1 1 0 Myosin tail DUF3584 PF12128.3 KFM05666.1 - 0.34 8.2 37.4 0.0082 13.5 20.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) NPV_P10 PF05531.7 KFM05666.1 - 0.45 10.8 11.7 5.1 7.4 1.0 3.5 1 1 3 4 4 4 0 Nucleopolyhedrovirus P10 protein Cluap1 PF10234.4 KFM05666.1 - 0.51 9.4 32.1 3 6.9 11.3 2.5 1 1 1 2 2 2 0 Clusterin-associated protein-1 TelA PF05816.6 KFM05666.1 - 0.65 8.6 22.9 0.32 9.6 1.9 2.5 2 1 0 3 3 3 0 Toxic anion resistance protein (TelA) Mod_r PF07200.8 KFM05666.1 - 0.67 9.8 36.1 2.1 8.2 5.4 3.3 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Hemerythrin PF01814.18 KFM05666.1 - 0.7 10.0 8.7 0.23 11.6 3.2 2.2 3 0 0 3 3 2 0 Hemerythrin HHE cation binding domain ADIP PF11559.3 KFM05666.1 - 0.72 9.7 45.3 0.33 10.8 2.8 4.0 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding DUF948 PF06103.6 KFM05666.1 - 0.74 9.7 13.5 1.3 8.9 1.4 3.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) WEMBL PF05701.6 KFM05666.1 - 0.78 8.1 39.2 1.3 7.4 24.5 2.4 2 1 0 2 2 2 0 Weak chloroplast movement under blue light CENP-F_leu_zip PF10473.4 KFM05666.1 - 0.79 9.5 49.0 0.56 10.0 2.6 3.7 2 1 1 3 3 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF812 PF05667.6 KFM05666.1 - 0.84 8.0 38.8 16 3.8 27.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF4600 PF15372.1 KFM05666.1 - 0.85 9.8 31.3 0.068 13.3 7.7 3.5 2 1 2 4 4 4 0 Domain of unknown function (DUF4600) MAD PF05557.8 KFM05666.1 - 0.88 7.5 41.2 0.21 9.6 25.8 1.8 1 1 0 1 1 1 0 Mitotic checkpoint protein Prominin PF05478.6 KFM05666.1 - 1.2 6.5 17.5 0.2 9.1 9.7 1.5 2 0 0 2 2 2 0 Prominin Filament PF00038.16 KFM05666.1 - 1.4 8.3 36.1 0.72 9.2 12.5 2.8 1 1 1 3 3 3 0 Intermediate filament protein Lebercilin PF15619.1 KFM05666.1 - 1.4 8.2 42.3 0.097 12.0 11.5 3.4 2 1 2 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease EzrA PF06160.7 KFM05666.1 - 1.6 6.8 32.6 0.09 10.9 18.4 1.9 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA Fez1 PF06818.10 KFM05666.1 - 1.8 8.5 35.0 0.67 9.9 17.8 2.1 1 1 1 2 2 2 0 Fez1 TMEM192 PF14802.1 KFM05666.1 - 1.9 7.2 6.6 2.3 7.0 1.6 2.6 1 1 1 2 2 2 0 TMEM192 family DUF4200 PF13863.1 KFM05666.1 - 2.1 8.3 47.4 0.34 10.8 11.5 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) DUF972 PF06156.8 KFM05666.1 - 2.4 8.5 36.4 1.4 9.2 7.7 4.3 1 1 3 4 4 4 0 Protein of unknown function (DUF972) ING PF12998.2 KFM05666.1 - 2.6 8.3 26.4 1.1 9.5 4.7 3.3 2 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding TMF_TATA_bd PF12325.3 KFM05666.1 - 3.2 7.4 40.1 0.21 11.3 5.6 3.6 2 1 2 4 4 3 0 TATA element modulatory factor 1 TATA binding AAA_13 PF13166.1 KFM05666.1 - 3.4 5.9 34.3 28 2.9 24.2 1.9 1 1 1 2 2 2 0 AAA domain DUF3461 PF11944.3 KFM05666.1 - 3.5 7.5 16.8 0.17 11.7 3.8 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3461) MscS_porin PF12795.2 KFM05666.1 - 3.5 6.8 38.8 0.053 12.8 14.7 2.4 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain MerR-DNA-bind PF09278.6 KFM05666.1 - 3.7 8.0 18.3 0.61 10.5 0.8 4.6 2 2 2 4 4 4 0 MerR, DNA binding Leu_zip PF15294.1 KFM05666.1 - 4.1 6.4 40.6 0.94 8.5 20.3 2.4 1 1 1 2 2 2 0 Leucine zipper Dor1 PF04124.7 KFM05666.1 - 4.4 5.6 25.1 0.2 10.0 13.1 1.9 2 1 0 2 2 1 0 Dor1-like family Tropomyosin_1 PF12718.2 KFM05666.1 - 5.8 6.7 49.1 0.052 13.3 25.3 3.1 1 1 2 3 3 2 0 Tropomyosin like COG2 PF06148.6 KFM05666.1 - 6.1 6.7 19.1 40 4.0 4.7 3.7 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DASH_Dad2 PF08654.5 KFM05666.1 - 6.4 6.8 19.0 1.3 9.0 3.4 3.8 2 1 2 4 4 3 0 DASH complex subunit Dad2 Tnp_P_element PF12017.3 KFM05666.1 - 6.7 5.8 16.3 1.6 7.8 3.0 2.7 1 1 0 2 2 2 0 Transposase protein KLRAQ PF10205.4 KFM05666.1 - 7.1 6.7 32.8 5.6 7.0 6.6 4.4 2 1 3 5 5 5 0 Predicted coiled-coil domain-containing protein Sec34 PF04136.10 KFM05666.1 - 8.2 6.1 17.8 9.2 5.9 2.7 2.4 1 1 1 2 2 2 0 Sec34-like family TPR_MLP1_2 PF07926.7 KFM05666.1 - 8.5 6.1 48.4 0.23 11.1 4.1 4.0 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein RAM PF15320.1 KFM05667.1 - 1.6e-22 79.5 1.5 1.7e-22 79.4 1.1 1.0 1 0 0 1 1 1 1 mRNA cap methylation, RNMT-activating mini protein DUF167 PF02594.11 KFM05668.1 - 3.2e-18 65.4 0.5 3.9e-18 65.1 0.4 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 ALS_ss_C PF10369.4 KFM05668.1 - 0.046 13.4 0.2 0.1 12.3 0.1 1.6 1 1 0 1 1 1 0 Small subunit of acetolactate synthase PHR PF08005.7 KFM05669.1 - 2e-49 167.6 0.4 3e-49 167.0 0.3 1.3 1 0 0 1 1 1 1 PHR domain BACK PF07707.10 KFM05669.1 - 1.8e-09 37.3 0.2 3.4e-08 33.2 0.0 2.6 1 1 1 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.26 KFM05669.1 - 8.8e-07 28.8 0.3 2.1e-05 24.4 0.0 2.5 1 1 1 2 2 2 1 BTB/POZ domain DUF2781 PF10914.3 KFM05670.1 - 2.4e-36 124.7 4.5 2.4e-36 124.7 3.1 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF2781) EmrE PF13536.1 KFM05670.1 - 0.061 13.5 5.6 1.9 8.6 0.6 2.7 2 0 0 2 2 2 0 Multidrug resistance efflux transporter ApoM PF11032.3 KFM05670.1 - 0.069 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Apolipoprotein M (ApoM) PWWP PF00855.12 KFM05671.1 - 8.2e-08 32.3 0.0 8.2e-08 32.3 0.0 2.1 2 1 0 2 2 2 1 PWWP domain Pox_Ag35 PF03286.9 KFM05671.1 - 0.61 9.5 12.6 0.93 8.9 8.7 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FLO_LFY PF01698.11 KFM05671.1 - 1.8 7.3 12.8 2.2 7.0 8.9 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Raftlin PF15250.1 KFM05671.1 - 5.2 5.4 9.2 6.6 5.1 6.4 1.1 1 0 0 1 1 1 0 Raftlin zf-met PF12874.2 KFM05672.1 - 2.4e-11 43.3 21.0 0.0022 18.1 0.7 5.8 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 KFM05672.1 - 3.2e-11 42.7 34.1 0.0065 16.7 1.2 7.4 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM05672.1 - 4.7e-07 29.7 17.0 0.038 14.1 1.6 4.1 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 KFM05672.1 - 1.3e-06 28.3 40.4 0.0039 17.4 1.3 7.4 6 1 0 6 6 6 3 Zinc finger, C2H2 type zf-BED PF02892.10 KFM05672.1 - 4.9 6.9 17.9 4.3 7.1 1.6 4.0 3 0 0 3 3 3 0 BED zinc finger BAR PF03114.13 KFM05673.1 - 5.8e-75 251.7 8.3 6.9e-75 251.4 5.7 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 KFM05673.1 - 8.2e-15 53.9 0.1 2.5e-14 52.3 0.1 1.9 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFM05673.1 - 1.3e-14 53.4 0.1 2.3e-14 52.7 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFM05673.1 - 1.2e-13 50.3 0.0 2.8e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain BAR_2 PF10455.4 KFM05673.1 - 1.3e-07 30.8 4.5 2.9e-06 26.4 0.8 2.1 2 0 0 2 2 2 2 Bin/amphiphysin/Rvs domain for vesicular trafficking Filament PF00038.16 KFM05674.1 - 7.1e-54 183.3 47.9 6.2e-52 177.0 26.5 2.0 1 1 1 2 2 2 2 Intermediate filament protein LTD PF00932.14 KFM05674.1 - 1.4e-18 67.0 0.1 2.9e-18 66.0 0.1 1.5 1 0 0 1 1 1 1 Lamin Tail Domain STOP PF05217.7 KFM05675.1 - 3.2e-41 141.4 30.9 1.1e-25 90.5 6.6 3.9 1 1 3 4 4 4 4 STOP protein GTP_EFTU PF00009.22 KFM05676.1 - 5.3e-56 189.0 0.0 1.6e-55 187.4 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 KFM05676.1 - 2.1e-17 62.7 0.1 9.3e-17 60.6 0.0 2.2 3 0 0 3 3 3 1 Elongation factor G C-terminus EFG_II PF14492.1 KFM05676.1 - 8.1e-10 38.4 0.2 3e-09 36.5 0.0 2.1 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 KFM05676.1 - 1.6e-08 34.5 0.0 6.9e-08 32.4 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 KFM05676.1 - 3.2e-06 26.6 0.5 8.7e-05 22.0 0.0 3.1 2 1 0 2 2 2 1 Elongation factor G, domain IV Miro PF08477.8 KFM05676.1 - 0.046 14.2 0.1 0.2 12.1 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein TMC PF07810.8 KFM05677.1 - 6.4e-42 142.4 2.3 6.4e-42 142.4 1.6 2.4 2 0 0 2 2 2 1 TMC domain DUF912 PF06024.7 KFM05677.1 - 5.5 7.1 11.0 0.36 10.9 0.2 3.8 4 0 0 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) START PF01852.14 KFM05678.1 - 1.6e-17 63.5 0.0 1.8e-17 63.3 0.0 1.0 1 0 0 1 1 1 1 START domain PDZ PF00595.19 KFM05679.1 - 3.8e-23 81.4 0.9 7.6e-13 48.4 0.2 2.7 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM05679.1 - 2.9e-07 30.2 0.3 0.00025 20.8 0.2 2.9 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.19 KFM05680.1 - 1.2e-29 102.2 0.2 1.7e-18 66.5 0.0 2.6 3 0 0 3 3 3 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM05680.1 - 2.5e-09 36.8 0.0 0.00034 20.4 0.0 2.6 2 1 0 2 2 2 2 PDZ domain Mesd PF10185.4 KFM05683.1 - 1.5e-68 229.4 0.6 1.8e-68 229.1 0.5 1.2 1 0 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor PSII_BNR PF14870.1 KFM05683.1 - 0.059 12.3 0.0 0.17 10.8 0.0 1.6 1 1 1 2 2 2 0 Photosynthesis system II assembly factor YCF48 Toxin_14 PF07829.6 KFM05684.1 - 5.9 6.7 6.0 1.4e+02 2.2 0.1 3.8 3 0 0 3 3 3 0 Alpha-A conotoxin PIVA-like protein G8 PF10162.4 KFM05685.1 - 1.8e-28 98.8 0.1 3.4e-28 97.9 0.0 1.5 1 0 0 1 1 1 1 G8 domain Mucin2_WxxW PF13330.1 KFM05685.1 - 4.1e-12 46.3 0.7 4.6e-11 42.9 0.1 2.4 2 0 0 2 2 2 1 Mucin-2 protein WxxW repeating region Beta_helix PF13229.1 KFM05685.1 - 0.0027 17.4 6.2 0.86 9.3 0.0 4.5 4 2 0 4 4 4 2 Right handed beta helix region Abhydrolase_5 PF12695.2 KFM05686.1 - 1.3e-29 102.7 0.0 2e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFM05686.1 - 8.6e-15 55.2 0.1 1.3e-07 31.7 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFM05686.1 - 1.4e-07 31.3 0.0 0.015 14.8 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFM05686.1 - 4.2e-07 29.3 0.0 1.5e-05 24.3 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 KFM05686.1 - 9.3e-05 21.8 0.0 0.00016 21.0 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family UPF0227 PF05728.7 KFM05686.1 - 0.00063 19.5 0.0 0.012 15.4 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) DUF818 PF05677.7 KFM05686.1 - 0.00097 17.9 0.1 0.0015 17.3 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) FSH1 PF03959.8 KFM05686.1 - 0.0062 15.9 0.0 0.0095 15.3 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 KFM05686.1 - 0.007 15.8 0.0 0.03 13.7 0.0 2.0 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase RNA_ligase PF09414.5 KFM05686.1 - 0.075 12.8 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 RNA ligase Abhydrolase_4 PF08386.5 KFM05686.1 - 0.11 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein PAS_11 PF14598.1 KFM05687.1 - 1.5e-24 86.0 0.2 8.8e-20 70.7 0.1 2.9 2 1 1 3 3 3 2 PAS domain PAS_3 PF08447.6 KFM05687.1 - 1.2e-23 83.0 0.0 2.3e-17 62.8 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS PF00989.19 KFM05687.1 - 1.6e-23 82.6 0.0 8e-14 51.3 0.0 2.4 2 0 0 2 2 2 2 PAS fold HLH PF00010.21 KFM05687.1 - 7e-15 54.4 1.1 1.6e-14 53.2 0.8 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.1 KFM05687.1 - 2e-10 40.9 0.0 6e-09 36.2 0.0 2.5 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 KFM05687.1 - 3.5e-05 23.8 0.0 0.11 12.5 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_6 PF08348.6 KFM05687.1 - 0.049 13.2 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 YheO-like PAS domain FAA_hydrolase PF01557.13 KFM05688.1 - 2.4e-51 174.2 0.0 3.2e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 KFM05688.1 - 1.3e-35 121.5 0.0 3.1e-35 120.3 0.0 1.6 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal zf-A20 PF01754.11 KFM05689.1 - 8.2e-13 47.6 7.7 2.1e-12 46.3 5.3 1.8 1 0 0 1 1 1 1 A20-like zinc finger zf-AN1 PF01428.11 KFM05689.1 - 1.6e-11 43.8 6.0 1.6e-11 43.8 4.2 2.2 3 0 0 3 3 3 1 AN1-like Zinc finger Bcl-2 PF00452.14 KFM05690.1 - 2.8e-25 88.3 0.1 4.4e-25 87.7 0.1 1.3 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family 5-FTHF_cyc-lig PF01812.15 KFM05691.1 - 2.5e-46 157.7 0.0 2.8e-46 157.6 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family UPF0258 PF06789.7 KFM05692.1 - 2.3e-78 261.7 2.2 6.5e-78 260.2 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0258) Alveol-reg_P311 PF11092.3 KFM05692.1 - 0.069 13.1 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 Neuronal protein 3.1 (p311) PEX11 PF05648.9 KFM05694.1 - 5.9e-61 205.5 0.1 6.6e-61 205.4 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Perilipin PF03036.11 KFM05695.1 - 3.9e-56 190.5 0.2 4.4e-56 190.4 0.2 1.0 1 0 0 1 1 1 1 Perilipin family Ras PF00071.17 KFM05696.1 - 9.8e-18 64.0 0.0 1.1e-17 63.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM05696.1 - 5e-12 46.3 0.0 6.1e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM05696.1 - 0.074 12.2 0.0 0.13 11.4 0.0 1.5 1 1 0 1 1 1 0 ADP-ribosylation factor family Kinesin PF00225.18 KFM05697.1 - 2.4e-78 263.2 0.1 2.4e-78 263.2 0.1 3.2 3 0 0 3 3 3 1 Kinesin motor domain FANCI_S4 PF14678.1 KFM05699.1 - 5.2e-102 340.3 6.8 7e-102 339.9 3.3 2.3 2 0 0 2 2 2 1 FANCI solenoid 4 FANCI_HD2 PF14680.1 KFM05699.1 - 2.7e-100 334.3 3.8 2.7e-100 334.3 2.7 2.4 2 0 0 2 2 2 1 FANCI helical domain 2 FANCI_S3 PF14677.1 KFM05699.1 - 7.6e-88 293.5 2.3 7.6e-88 293.5 1.6 2.8 3 0 0 3 3 3 1 FANCI solenoid 3 FANCI_S1 PF14675.1 KFM05699.1 - 5.7e-77 258.0 0.4 2e-76 256.2 0.2 2.0 1 0 0 1 1 1 1 FANCI solenoid 1 FANCI_S2 PF14676.1 KFM05699.1 - 1.5e-53 180.8 0.1 1.5e-53 180.8 0.1 4.1 4 1 1 5 5 5 1 FANCI solenoid 2 FANCI_HD1 PF14679.1 KFM05699.1 - 3.9e-32 109.8 0.3 1.7e-31 107.7 0.2 2.3 1 0 0 1 1 1 1 FANCI helical domain 1 FANCI_S1-cap PF14674.1 KFM05699.1 - 0.0017 18.3 0.1 0.0089 16.0 0.1 2.4 1 0 0 1 1 1 1 FANCI solenoid 1 cap CRAL_TRIO PF00650.15 KFM05700.1 - 6.4e-38 129.7 0.0 9.3e-38 129.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 KFM05700.1 - 3.9e-12 46.3 0.0 6.9e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KFM05700.1 - 8.1e-08 32.2 1.1 4e-07 30.0 0.8 2.4 1 1 0 1 1 1 1 CRAL/TRIO, N-terminal domain APG6 PF04111.7 KFM05700.1 - 0.088 11.8 0.2 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Abhydrolase_1 PF00561.15 KFM05701.1 - 4.2e-23 82.1 0.0 6e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KFM05701.1 - 8.3e-10 38.9 0.0 1.3e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFM05701.1 - 3.8e-06 26.7 0.0 5.7e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 KFM05701.1 - 0.0026 17.4 0.1 0.0055 16.4 0.0 1.5 1 0 0 1 1 1 1 Cutinase Ndr PF03096.9 KFM05701.1 - 0.0045 15.5 0.0 0.0065 14.9 0.0 1.1 1 0 0 1 1 1 1 Ndr family DUF915 PF06028.6 KFM05701.1 - 0.018 14.1 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) VirJ PF06057.6 KFM05701.1 - 0.03 14.1 0.1 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Lipase_3 PF01764.20 KFM05701.1 - 0.047 13.3 0.0 0.088 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) F5_F8_type_C PF00754.20 KFM05702.1 - 4.4e-61 204.3 3.1 6.2e-31 106.9 1.6 2.1 2 0 0 2 2 2 2 F5/8 type C domain EGF PF00008.22 KFM05702.1 - 1.8e-22 78.8 46.2 3.4e-10 39.6 5.9 3.8 4 0 0 4 4 4 3 EGF-like domain EGF_2 PF07974.8 KFM05702.1 - 3.9e-09 36.5 37.2 0.0021 18.1 5.5 4.1 3 2 0 3 3 3 3 EGF-like domain hEGF PF12661.2 KFM05702.1 - 0.00073 19.4 19.4 0.017 15.2 1.3 4.0 3 0 0 3 3 3 2 Human growth factor-like EGF EGF_3 PF12947.2 KFM05702.1 - 0.32 10.9 34.2 0.17 11.9 7.2 4.2 2 1 1 3 3 3 0 EGF domain FXa_inhibition PF14670.1 KFM05702.1 - 1.4 9.0 32.5 0.63 10.2 2.0 4.0 1 1 2 3 3 3 0 Coagulation Factor Xa inhibitory site EGF_CA PF07645.10 KFM05702.1 - 3.7 7.6 38.0 0.045 13.7 5.6 4.1 1 1 2 3 3 3 0 Calcium-binding EGF domain Xlink PF00193.12 KFM05703.1 - 8e-53 176.4 0.1 5.3e-31 106.5 0.0 2.3 2 0 0 2 2 2 2 Extracellular link domain V-set PF07686.12 KFM05703.1 - 1.3e-11 44.3 0.0 2.1e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 KFM05703.1 - 0.00038 20.2 0.0 0.00075 19.2 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM05703.1 - 0.0012 18.9 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Lectin_C PF00059.16 KFM05703.1 - 0.0023 18.5 0.3 0.77 10.4 0.0 2.4 2 0 0 2 2 2 2 Lectin C-type domain Ig_3 PF13927.1 KFM05703.1 - 0.009 16.4 0.0 0.084 13.3 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin domain Chordopox_A33R PF05966.7 KFM05703.1 - 0.022 13.5 0.0 0.58 8.8 0.0 2.1 2 0 0 2 2 2 0 Chordopoxvirus A33R protein ig PF00047.20 KFM05703.1 - 0.023 14.8 0.0 0.1 12.7 0.0 2.0 1 1 0 1 1 1 0 Immunoglobulin domain Xlink PF00193.12 KFM05704.1 - 1e-140 458.2 18.6 7.6e-38 128.4 0.7 5.0 5 0 0 5 5 5 4 Extracellular link domain Lectin_C PF00059.16 KFM05704.1 - 1.4e-22 80.3 16.1 2.6e-19 69.8 1.9 5.1 5 0 0 5 5 5 2 Lectin C-type domain Sushi PF00084.15 KFM05704.1 - 6.7e-11 42.3 2.0 1.8e-10 40.9 1.4 1.8 1 0 0 1 1 1 1 Sushi domain (SCR repeat) V-set PF07686.12 KFM05704.1 - 5e-09 36.0 0.0 1.4e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin V-set domain EGF PF00008.22 KFM05704.1 - 9.1e-06 25.5 4.2 3e-05 23.8 2.9 2.0 1 0 0 1 1 1 1 EGF-like domain Chordopox_A33R PF05966.7 KFM05704.1 - 0.011 14.5 4.5 0.91 8.2 0.1 4.0 4 0 0 4 4 4 0 Chordopoxvirus A33R protein EGF_CA PF07645.10 KFM05704.1 - 0.03 14.2 8.6 0.062 13.3 4.8 2.5 2 1 0 2 2 2 0 Calcium-binding EGF domain EGF_2 PF07974.8 KFM05704.1 - 4 7.6 6.1 15 5.8 4.2 2.1 1 0 0 1 1 1 0 EGF-like domain RNase_T PF00929.19 KFM05705.1 - 4.1e-29 101.9 0.0 5.5e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 KFM05705.1 - 3.7e-05 23.2 0.0 9.2e-05 21.9 0.0 1.6 1 1 0 1 1 1 1 3'-5' exonuclease Det1 PF09737.4 KFM05706.1 - 1.2e-184 613.8 0.6 1.4e-184 613.5 0.4 1.1 1 0 0 1 1 1 1 De-etiolated protein 1 Det1 Ribosomal_S11 PF00411.14 KFM05707.1 - 2.7e-29 101.5 1.5 4.2e-29 100.9 1.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 MRP-L46 PF11788.3 KFM05708.1 - 7.4e-15 55.5 0.7 1.3e-14 54.8 0.5 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 Pkinase_Tyr PF07714.12 KFM05709.1 - 2.6e-91 305.2 0.1 5.4e-54 182.9 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 KFM05709.1 - 6.3e-47 159.8 0.0 2.5e-46 157.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain I-set PF07679.11 KFM05709.1 - 3.7e-13 49.1 0.0 9.8e-07 28.5 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM05709.1 - 7.7e-09 35.5 0.1 0.0036 17.3 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 KFM05709.1 - 0.00018 21.5 0.0 0.029 14.5 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.1 KFM05709.1 - 0.00099 19.5 0.6 0.98 9.9 0.1 2.7 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.7 KFM05709.1 - 0.0021 17.9 0.0 0.26 11.2 0.0 2.5 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain LRR_8 PF13855.1 KFM05709.1 - 0.036 13.8 0.5 0.092 12.5 0.4 1.7 1 0 0 1 1 1 0 Leucine rich repeat SKG6 PF08693.5 KFM05709.1 - 0.17 11.1 0.4 0.35 10.2 0.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Peptidase_M14 PF00246.19 KFM05710.1 - 1e-23 84.3 0.0 1.9e-23 83.4 0.0 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.9 KFM05710.1 - 0.057 12.3 0.0 0.087 11.6 0.0 1.2 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Kelch_1 PF01344.20 KFM05711.1 - 1.9e-55 184.1 0.9 6e-12 44.9 0.0 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 KFM05711.1 - 2.2e-33 113.0 2.1 7.4e-07 29.0 0.0 6.2 2 2 4 6 6 6 5 Kelch motif BACK PF07707.10 KFM05711.1 - 4.8e-33 113.0 3.3 5.9e-33 112.7 1.3 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_3 PF13415.1 KFM05711.1 - 1.9e-28 97.8 0.2 1.7e-07 31.1 0.0 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain BTB PF00651.26 KFM05711.1 - 5.3e-26 90.7 0.3 1.1e-25 89.7 0.1 1.7 2 0 0 2 2 2 1 BTB/POZ domain Kelch_4 PF13418.1 KFM05711.1 - 4.3e-25 87.2 1.7 4.1e-09 36.0 0.0 5.8 4 2 1 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.10 KFM05711.1 - 2e-24 84.3 6.0 0.00016 21.3 0.0 6.3 5 1 0 5 5 5 5 Kelch motif Kelch_5 PF13854.1 KFM05711.1 - 4e-17 61.7 0.5 1.1e-08 34.8 0.0 5.8 6 0 0 6 6 6 3 Kelch motif DUF3342 PF11822.3 KFM05711.1 - 0.0036 16.4 0.1 0.0091 15.1 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3342) DUF1668 PF07893.8 KFM05711.1 - 0.0059 15.7 0.2 0.029 13.5 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1668) Root_cap PF06830.6 KFM05711.1 - 0.045 13.5 0.0 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 Root cap Rax2 PF12768.2 KFM05711.1 - 0.14 11.2 0.1 7.7 5.6 0.0 2.6 2 1 0 3 3 3 0 Cortical protein marker for cell polarity RhoGEF PF00621.15 KFM05712.1 - 9.4e-34 116.8 7.0 9.4e-34 116.8 4.9 2.6 3 0 0 3 3 3 1 RhoGEF domain PH PF00169.24 KFM05712.1 - 1.5e-06 28.3 0.0 8.6e-06 25.9 0.0 2.4 1 0 0 1 1 1 1 PH domain C1_1 PF00130.17 KFM05712.1 - 5.8e-05 22.7 7.4 0.00011 21.8 5.2 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 KFM05712.1 - 0.00037 20.1 6.0 0.00074 19.1 4.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 PH_7 PF15408.1 KFM05712.1 - 0.0038 17.0 0.1 0.01 15.6 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Ank_2 PF12796.2 KFM05713.1 - 0.0063 16.8 0.0 0.017 15.4 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) MFS_1 PF07690.11 KFM05714.1 - 4.3e-38 130.9 27.8 3.7e-25 88.3 11.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFM05714.1 - 1.4e-33 116.2 24.2 3.1e-30 105.1 6.8 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter Pentapeptide_4 PF13599.1 KFM05714.1 - 4.9e-12 45.4 6.7 8.6e-12 44.7 4.6 1.3 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 KFM05714.1 - 2.1e-05 24.2 7.4 0.0017 18.1 0.7 2.8 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) DUF1228 PF06779.9 KFM05714.1 - 0.0016 18.4 2.0 0.0016 18.4 1.4 2.7 4 0 0 4 4 4 1 Protein of unknown function (DUF1228) Neurensin PF14927.1 KFM05714.1 - 0.041 13.2 0.0 0.13 11.6 0.0 1.9 1 0 0 1 1 1 0 Neurensin Pentapeptide PF00805.17 KFM05714.1 - 0.091 12.0 0.0 0.25 10.6 0.0 1.7 1 1 0 1 1 1 0 Pentapeptide repeats (8 copies) MFS_3 PF05977.8 KFM05714.1 - 0.32 9.0 8.3 0.85 7.6 1.2 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector OATP PF03137.15 KFM05715.1 - 2.5e-189 629.8 2.4 3e-189 629.5 1.6 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 KFM05715.1 - 2.1e-26 92.4 8.4 2.1e-26 92.4 5.8 2.9 2 2 0 2 2 2 2 Major Facilitator Superfamily Kazal_2 PF07648.10 KFM05715.1 - 8.6e-06 25.5 9.3 9.4e-06 25.4 4.3 2.5 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 KFM05715.1 - 0.0024 17.8 9.0 0.0024 17.8 6.2 2.1 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain PUCC PF03209.10 KFM05715.1 - 0.11 11.2 0.1 0.11 11.2 0.1 3.9 4 0 0 4 4 4 0 PUCC protein Glyco_transf_29 PF00777.13 KFM05716.1 - 6.3e-75 251.7 0.0 6.9e-75 251.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) DUF1180 PF06679.7 KFM05717.1 - 1.4e-20 73.8 1.4 1.4e-20 73.7 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) SNF2_N PF00176.18 KFM05718.1 - 2e-74 250.1 1.0 4.8e-74 248.8 0.7 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 KFM05718.1 - 3.7e-33 112.9 7.5 2.3e-20 71.9 0.0 4.0 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.1 KFM05718.1 - 2.6e-31 107.8 1.0 2.6e-31 107.8 0.7 3.5 4 0 0 4 4 4 1 Domain of unknown function (DUF4208) Helicase_C PF00271.26 KFM05718.1 - 1.7e-14 53.4 0.0 5.1e-14 51.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Myb_DNA-binding PF00249.26 KFM05718.1 - 0.00061 19.7 0.1 0.08 13.0 0.0 2.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain RGM_C PF06534.8 KFM05719.1 - 9.1e-75 249.7 0.0 1.5e-74 249.0 0.0 1.3 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) C-terminus RGM_N PF06535.7 KFM05719.1 - 2.7e-68 229.0 1.2 4e-68 228.5 0.8 1.3 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) N-terminus DAN PF03045.10 KFM05720.1 - 0.0058 16.0 0.1 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 DAN domain MGC-24 PF05283.6 KFM05720.1 - 0.0096 15.7 0.5 0.012 15.4 0.4 1.1 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24) C2 PF00168.25 KFM05721.1 - 6.4e-29 99.6 1.6 3.2e-20 71.7 0.1 2.1 2 0 0 2 2 2 2 C2 domain PI3K_C2 PF00792.19 KFM05721.1 - 0.11 12.2 0.0 2.9 7.6 0.0 2.3 2 0 0 2 2 2 0 Phosphoinositide 3-kinase C2 NT-C2 PF10358.4 KFM05721.1 - 0.12 11.8 0.0 0.75 9.2 0.0 2.1 2 1 0 2 2 2 0 N-terminal C2 in EEIG1 and EHBP1 proteins Hormone_recep PF00104.25 KFM05722.1 - 1.2e-41 142.0 0.1 1.7e-41 141.5 0.1 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFM05722.1 - 6.5e-31 106.3 17.1 6.5e-31 106.3 11.8 1.7 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Arrestin_C PF02752.17 KFM05724.1 - 8.1e-21 74.5 0.1 1e-19 70.9 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KFM05724.1 - 6.8e-17 61.6 0.1 5.5e-16 58.7 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Vps26 PF03643.10 KFM05724.1 - 0.095 11.4 0.0 0.15 10.8 0.0 1.4 1 1 0 1 1 1 0 Vacuolar protein sorting-associated protein 26 AMP-binding PF00501.23 KFM05725.1 - 2.5e-91 306.1 0.1 3.2e-91 305.8 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFM05725.1 - 0.00086 20.2 0.0 0.0024 18.8 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain DAGAT PF03982.8 KFM05726.1 - 5.6e-121 402.8 0.1 7e-121 402.4 0.1 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase B3_4 PF03483.12 KFM05727.1 - 5.1e-28 97.6 0.1 9.1e-28 96.8 0.1 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 KFM05727.1 - 1.5e-15 56.7 0.0 1.9e-14 53.2 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetase B5 domain PAP2 PF01569.16 KFM05728.1 - 7.2e-19 67.7 2.6 7.2e-19 67.7 1.8 1.9 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 KFM05728.1 - 0.00097 18.7 1.6 0.0027 17.2 1.1 1.7 1 0 0 1 1 1 1 PAP2 superfamily PAX PF00292.13 KFM05729.1 - 6e-45 152.0 1.3 6e-45 152.0 0.9 1.5 2 0 0 2 2 2 1 'Paired box' domain Pax7 PF12360.3 KFM05729.1 - 1.1e-23 83.2 7.8 2.9e-23 81.8 5.4 1.8 1 0 0 1 1 1 1 Paired box protein 7 Homeobox PF00046.24 KFM05729.1 - 6.4e-23 80.1 6.7 1.1e-22 79.4 4.6 1.4 1 0 0 1 1 1 1 Homeobox domain HTH_23 PF13384.1 KFM05729.1 - 9.2e-06 25.1 1.0 0.00054 19.5 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain Homeobox_KN PF05920.6 KFM05729.1 - 0.00032 20.3 0.4 0.00073 19.1 0.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain WD40 PF00400.27 KFM05730.1 - 2.3e-53 176.2 33.3 2.9e-07 30.1 0.0 12.8 13 1 0 13 13 13 10 WD domain, G-beta repeat PD40 PF07676.7 KFM05730.1 - 2.8 7.7 5.0 1.3e+02 2.4 0.0 4.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Vinculin PF01044.14 KFM05731.1 - 8.9e-53 179.5 21.9 3e-32 111.6 5.4 3.5 2 1 0 3 3 3 3 Vinculin family WXG100 PF06013.7 KFM05731.1 - 0.21 11.5 6.5 0.062 13.3 0.9 3.0 3 0 0 3 3 3 0 Proteins of 100 residues with WXG COG5 PF10392.4 KFM05731.1 - 0.48 10.3 9.5 0.18 11.7 1.7 3.7 3 2 1 4 4 4 0 Golgi transport complex subunit 5 GCV_H PF01597.14 KFM05732.1 - 6.6e-08 32.2 0.0 9.7e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Glycine cleavage H-protein SapB_1 PF05184.10 KFM05732.1 - 0.0047 16.7 0.1 0.011 15.4 0.0 1.7 2 0 0 2 2 2 1 Saposin-like type B, region 1 Zip PF02535.17 KFM05733.1 - 7.4e-102 340.5 31.0 1.5e-101 339.5 10.2 2.4 2 0 0 2 2 2 2 ZIP Zinc transporter Kazal_2 PF07648.10 KFM05734.1 - 1e-18 66.9 14.6 1.5e-11 43.9 2.5 3.8 4 0 0 4 4 4 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 KFM05734.1 - 1.1e-16 60.5 27.5 1.4e-09 37.8 6.7 3.9 2 2 0 2 2 2 2 Kazal-type serine protease inhibitor domain hEGF PF12661.2 KFM05734.1 - 0.002 18.0 3.3 0.002 18.0 2.3 3.1 3 0 0 3 3 3 1 Human growth factor-like EGF EphA2_TM PF14575.1 KFM05734.1 - 0.043 14.2 0.1 0.11 12.9 0.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.6 KFM05734.1 - 0.062 12.9 0.2 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Protocadherin PTRF_SDPR PF15237.1 KFM05735.1 - 9.2e-88 293.7 17.8 1.3e-87 293.3 12.3 1.2 1 0 0 1 1 1 1 PTRF/SDPR family MCPsignal PF00015.16 KFM05735.1 - 0.011 15.2 3.9 0.011 15.2 2.7 2.8 2 2 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Microcephalin PF12258.3 KFM05735.1 - 0.015 14.3 0.3 0.015 14.3 0.2 1.9 2 0 0 2 2 2 0 Microcephalin protein Syntaxin-6_N PF09177.6 KFM05735.1 - 0.62 10.5 13.2 3.3 8.1 3.1 3.4 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DUF1664 PF07889.7 KFM05735.1 - 0.66 9.7 11.5 0.22 11.3 4.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.6 KFM05735.1 - 1.8 8.4 6.3 7.2 6.5 0.7 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Syntaxin_2 PF14523.1 KFM05735.1 - 2.8 8.0 20.6 0.28 11.2 1.9 3.2 2 1 1 3 3 3 0 Syntaxin-like protein DHC_N1 PF08385.7 KFM05736.1 - 2.2e-42 145.2 1.1 2.4e-42 145.0 0.8 1.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 FerA PF08165.6 KFM05736.1 - 0.14 11.8 2.3 20 4.9 0.0 3.2 3 0 0 3 3 3 0 FerA (NUC095) domain Sec6 PF06046.8 KFM05737.1 - 5e-156 520.0 15.6 5e-156 520.0 10.8 1.4 2 0 0 2 2 2 1 Exocyst complex component Sec6 EF-hand_1 PF00036.27 KFM05738.1 - 2e-25 86.1 3.8 2e-07 29.7 0.1 5.3 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.1 KFM05738.1 - 6.9e-22 77.3 4.7 6.3e-12 45.4 0.6 3.5 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 KFM05738.1 - 4.5e-21 72.7 3.2 1.3e-06 27.7 0.0 5.2 5 0 0 5 5 5 5 EF-hand domain EF-hand_8 PF13833.1 KFM05738.1 - 5.6e-20 70.7 5.4 1.3e-06 27.9 0.0 5.0 2 2 3 5 5 5 5 EF-hand domain pair EF-hand_5 PF13202.1 KFM05738.1 - 1.4e-11 43.1 4.3 0.0006 19.0 0.0 3.9 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 KFM05738.1 - 0.064 13.1 0.1 1.6 8.7 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain PAS PF00989.19 KFM05741.1 - 6.8e-11 41.9 0.0 1.5e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.1 KFM05741.1 - 4.4e-07 29.8 0.3 0.00071 19.5 0.0 2.6 2 0 0 2 2 2 2 PAS domain HLH PF00010.21 KFM05741.1 - 5.3e-05 22.8 0.0 0.00012 21.6 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_3 PF08447.6 KFM05741.1 - 6.9e-05 22.8 0.3 0.056 13.5 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.5 KFM05741.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 PAS fold Myb_DNA-bind_5 PF13873.1 KFM05742.1 - 7.6e-22 77.0 2.0 7.6e-22 77.0 1.4 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.4 KFM05742.1 - 0.019 15.1 2.1 0.019 15.1 1.4 2.8 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like AIPR PF10592.4 KFM05742.1 - 0.12 11.6 4.6 0.23 10.7 3.2 1.6 1 1 0 1 1 1 0 AIPR protein DUSP PF06337.7 KFM05742.1 - 0.34 11.3 2.3 3.3 8.1 0.0 3.2 2 2 0 2 2 2 0 DUSP domain Myb_DNA-bind_3 PF12776.2 KFM05742.1 - 1.8 9.2 9.9 10 6.8 0.5 2.7 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain zf-C2H2_jaz PF12171.3 KFM05743.1 - 0.00033 20.6 0.9 0.00033 20.6 0.6 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM05743.1 - 0.0013 18.8 2.0 0.0013 18.8 1.4 3.2 3 1 0 3 3 3 1 Zinc-finger of C2H2 type Ipi1_N PF12333.3 KFM05744.1 - 8.6e-20 70.6 0.9 8.6e-20 70.6 0.6 3.9 4 1 1 5 5 5 1 Rix1 complex component involved in 60S ribosome maturation Cnd1 PF12717.2 KFM05744.1 - 0.00015 21.6 0.1 0.00088 19.1 0.0 2.3 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 KFM05744.1 - 0.015 15.7 1.0 0.23 12.0 0.0 3.6 4 1 0 4 4 4 0 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KFM05744.1 - 0.017 15.5 0.0 0.11 12.9 0.0 2.5 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region DUF2474 PF10617.4 KFM05744.1 - 0.96 9.0 4.1 16 5.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2474) Thioredoxin_6 PF13848.1 KFM05745.1 - 1e-46 159.0 0.3 1.1e-41 142.6 0.1 2.3 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.15 KFM05745.1 - 3.5e-21 74.8 0.0 8.4e-21 73.6 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin Calsequestrin PF01216.12 KFM05745.1 - 1.6e-08 33.7 0.2 2e-08 33.4 0.1 1.3 1 0 0 1 1 1 1 Calsequestrin Thioredoxin_2 PF13098.1 KFM05745.1 - 4.9e-05 23.4 0.0 0.00021 21.4 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KFM05745.1 - 9.2e-05 22.4 0.7 0.00062 19.8 0.1 2.5 2 1 0 2 2 2 1 Thioredoxin-like HyaE PF07449.6 KFM05745.1 - 0.00014 21.7 0.0 0.00044 20.1 0.0 1.8 1 1 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.1 KFM05745.1 - 0.018 15.0 0.1 0.31 11.1 0.1 2.4 2 0 0 2 2 2 0 Thioredoxin-like SNARE PF05739.14 KFM05746.1 - 1.7e-11 43.5 1.4 2.8e-11 42.9 0.1 1.9 2 0 0 2 2 2 1 SNARE domain Gly-zipper_OmpA PF13436.1 KFM05746.1 - 0.0032 17.1 2.1 0.0057 16.3 1.5 1.3 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain Vac_Fusion PF02346.11 KFM05746.1 - 0.021 14.2 0.6 0.067 12.6 0.0 2.1 2 0 0 2 2 2 0 Chordopoxvirus fusion protein RseC_MucC PF04246.7 KFM05746.1 - 0.055 13.0 0.1 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC DUF1469 PF07332.6 KFM05746.1 - 0.37 10.5 3.1 0.47 10.1 1.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1469) Gly-zipper_YMGG PF13441.1 KFM05746.1 - 0.53 9.8 15.7 0.88 9.1 10.9 1.2 1 0 0 1 1 1 0 YMGG-like Gly-zipper TraT PF05818.7 KFM05746.1 - 0.57 9.5 2.9 1 8.7 2.0 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein GrpE PF01025.14 KFM05746.1 - 3.8 7.0 7.2 0.95 8.9 1.0 2.2 2 1 0 2 2 2 0 GrpE zf-C4 PF00105.13 KFM05747.1 - 3.1e-31 107.4 18.2 5.5e-31 106.6 12.6 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 KFM05747.1 - 3e-17 62.4 0.0 5.8e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor C9orf72-like PF15019.1 KFM05747.1 - 0.014 14.6 0.0 0.026 13.7 0.0 1.4 1 0 0 1 1 1 0 C9orf72-like protein family Yae1_N PF09811.4 KFM05749.1 - 8.1e-21 73.2 64.5 1.5e+04 -25.1 44.7 5.8 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Sec61_beta PF03911.11 KFM05750.1 - 1e-21 76.4 0.0 1.3e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 Sec61beta family Glycos_transf_1 PF00534.15 KFM05751.1 - 3.5e-37 127.4 0.0 5.4e-37 126.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KFM05751.1 - 9.3e-10 38.7 0.0 1.6e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KFM05751.1 - 1.5e-06 28.3 0.0 5.5e-06 26.5 0.0 2.0 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KFM05751.1 - 0.0019 18.3 0.1 0.0054 16.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Ifi-6-16 PF06140.8 KFM05752.1 - 3.3e-25 87.6 23.7 4.6e-14 51.9 6.8 2.0 1 1 1 2 2 2 2 Interferon-induced 6-16 family Arabino_trans_C PF14896.1 KFM05752.1 - 0.11 11.1 1.7 0.13 10.8 1.0 1.3 1 1 0 1 1 1 0 EmbC C-terminal domain CAP PF00188.21 KFM05753.1 - 4.9e-22 78.7 0.6 5.9e-22 78.4 0.4 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family BLOC1_2 PF10046.4 KFM05755.1 - 0.015 15.4 0.2 0.091 12.9 0.0 2.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AIP3 PF03915.8 KFM05755.1 - 0.033 13.0 0.5 0.045 12.6 0.3 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 Sec8_exocyst PF04048.9 KFM05755.1 - 0.045 13.3 0.1 0.054 13.1 0.1 1.1 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain MtrG PF04210.8 KFM05755.1 - 0.052 13.2 0.2 0.2 11.3 0.0 1.9 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Med4 PF10018.4 KFM05755.1 - 0.054 12.8 0.0 0.28 10.5 0.0 1.8 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 CAP_C PF08603.6 KFM05755.1 - 0.078 12.3 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal PDZ PF00595.19 KFM05756.1 - 5.7e-11 42.4 0.0 9.6e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PB1 PF00564.19 KFM05756.1 - 2.3e-10 39.9 0.0 5.7e-10 38.7 0.0 1.7 2 0 0 2 2 2 1 PB1 domain PDZ_2 PF13180.1 KFM05756.1 - 0.023 14.5 0.1 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 PDZ domain LRR_6 PF13516.1 KFM05757.1 - 7.2e-15 53.3 21.4 0.16 12.0 0.0 10.4 10 0 0 10 10 10 6 Leucine Rich repeat LRR_4 PF12799.2 KFM05757.1 - 4e-11 42.2 24.0 0.021 14.4 1.4 7.0 5 2 1 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM05757.1 - 0.00086 19.0 16.4 20 5.7 0.1 9.6 10 2 1 11 11 11 2 Leucine Rich Repeat Rep_fac_C PF08542.6 KFM05757.1 - 0.098 12.6 0.4 0.55 10.2 0.1 2.4 2 0 0 2 2 2 0 Replication factor C C-terminal domain HEAT_2 PF13646.1 KFM05758.1 - 1.6e-05 25.0 3.2 8.8e-05 22.7 0.2 2.7 1 1 0 1 1 1 1 HEAT repeats Arm PF00514.18 KFM05758.1 - 0.0015 18.3 3.7 0.52 10.2 0.0 3.4 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT PF02985.17 KFM05758.1 - 0.079 13.0 0.1 0.58 10.3 0.0 2.5 2 0 0 2 2 2 0 HEAT repeat HEAT_EZ PF13513.1 KFM05758.1 - 0.88 10.1 3.0 68 4.1 0.2 3.8 3 1 0 3 3 3 0 HEAT-like repeat Geminin PF07412.7 KFM05759.1 - 2e-86 288.8 12.3 2.2e-86 288.6 8.5 1.0 1 0 0 1 1 1 1 Geminin Snapin_Pallidin PF14712.1 KFM05759.1 - 0.012 15.8 0.5 0.03 14.6 0.4 1.6 1 0 0 1 1 1 0 Snapin/Pallidin Laminin_II PF06009.7 KFM05759.1 - 0.012 15.3 2.1 0.012 15.3 1.5 1.9 3 0 0 3 3 2 0 Laminin Domain II DivIC PF04977.10 KFM05759.1 - 0.03 13.7 1.9 0.03 13.7 1.3 2.0 1 1 1 2 2 2 0 Septum formation initiator UvsY PF11056.3 KFM05759.1 - 0.066 13.3 3.3 0.11 12.5 1.2 1.9 1 1 1 2 2 2 0 Recombination, repair and ssDNA binding protein UvsY DUF342 PF03961.8 KFM05759.1 - 0.077 11.3 5.0 0.091 11.1 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1342 PF07072.6 KFM05759.1 - 0.083 12.5 3.8 0.49 10.0 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1342) DUF1682 PF07946.9 KFM05759.1 - 0.085 11.6 5.0 0.11 11.3 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Aldedh PF00171.17 KFM05759.1 - 0.089 11.1 0.9 0.11 10.8 0.6 1.1 1 0 0 1 1 1 0 Aldehyde dehydrogenase family DUF3688 PF12461.3 KFM05759.1 - 0.12 12.7 2.6 0.19 12.1 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3688) Herpes_BLRF2 PF05812.7 KFM05759.1 - 0.15 11.8 10.4 0.47 10.2 1.3 2.8 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein DUF641 PF04859.7 KFM05759.1 - 0.35 10.6 5.7 0.17 11.6 2.0 1.8 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Val_tRNA-synt_C PF10458.4 KFM05759.1 - 0.84 9.7 13.1 0.79 9.8 0.5 3.1 2 1 2 4 4 4 0 Valyl tRNA synthetase tRNA binding arm DivIVA PF05103.8 KFM05759.1 - 1.3 9.0 8.1 0.34 10.9 2.8 2.0 2 0 0 2 2 2 0 DivIVA protein FAR1 PF03101.10 KFM05759.1 - 1.4 9.5 4.4 2.9 8.4 2.7 1.9 1 1 1 2 2 2 0 FAR1 DNA-binding domain HALZ PF02183.13 KFM05759.1 - 4.2 7.1 10.3 4.1 7.1 0.6 3.5 2 1 1 3 3 3 0 Homeobox associated leucine zipper Bap31 PF05529.7 KFM05759.1 - 4.4 6.7 6.6 9.1 5.6 4.6 1.6 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like IncA PF04156.9 KFM05759.1 - 6 6.4 7.0 7.9 6.0 4.9 1.3 1 0 0 1 1 1 0 IncA protein CCDC-167 PF15188.1 KFM05759.1 - 9.2 6.2 12.5 50 3.9 8.7 2.1 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF4566 PF15130.1 KFM05760.1 - 3e-147 488.2 2.1 3.4e-147 488.0 1.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4566) 4HBT PF03061.17 KFM05761.1 - 3.5e-14 52.6 0.1 5.3e-14 52.1 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 KFM05761.1 - 7.1e-06 25.9 0.1 8.9e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4442 PF14539.1 KFM05761.1 - 0.013 15.5 0.2 0.082 12.8 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4442) Exo_endo_phos PF03372.18 KFM05762.1 - 8.1e-17 61.9 0.0 1.1e-16 61.5 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UBA_4 PF14555.1 KFM05762.1 - 2.4e-08 33.3 0.0 4.4e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain 7tm_1 PF00001.16 KFM05763.1 - 4.1e-62 209.6 15.7 5e-62 209.3 10.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM05763.1 - 2.6e-09 36.6 13.4 3.2e-09 36.3 9.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.4 KFM05763.1 - 7.5e-08 31.8 14.2 1.1e-05 24.7 9.8 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.4 KFM05763.1 - 2.1e-05 23.8 12.0 2.7e-05 23.4 8.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srd PF10317.4 KFM05763.1 - 5.5e-05 22.2 19.0 0.0033 16.4 13.1 2.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd DUF962 PF06127.6 KFM05763.1 - 0.085 12.7 3.3 0.84 9.5 2.3 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF962) 60KD_IMP PF02096.15 KFM05763.1 - 0.25 10.9 2.1 0.5 9.9 1.4 1.7 1 1 0 1 1 1 0 60Kd inner membrane protein Bac_rhodopsin PF01036.13 KFM05763.1 - 0.6 9.3 12.1 0.13 11.5 3.9 2.2 2 1 0 2 2 2 0 Bacteriorhodopsin-like protein Myelin_MBP PF01669.12 KFM05764.1 - 4.8e-51 172.1 7.8 7.4e-51 171.5 5.4 1.3 1 0 0 1 1 1 1 Myelin basic protein zf-H2C2_2 PF13465.1 KFM05765.1 - 7e-75 243.8 99.5 4.2e-09 36.2 0.2 12.5 12 1 0 12 12 12 11 Zinc-finger double domain zf-C2H2 PF00096.21 KFM05765.1 - 1.1e-51 170.1 108.0 1.4e-06 28.2 1.7 12.1 11 1 1 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM05765.1 - 1.8e-38 128.0 87.3 0.00021 21.4 0.5 12.1 11 1 1 12 12 12 11 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM05765.1 - 1.1e-26 92.2 73.9 0.0002 21.4 2.5 12.1 11 1 1 12 12 12 8 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFM05765.1 - 1.7e-06 28.0 67.9 0.11 12.6 1.5 10.4 1 1 9 11 11 11 5 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 KFM05765.1 - 5.7e-06 26.3 73.0 0.00069 19.6 3.2 8.6 3 3 4 8 8 7 5 Drought induced 19 protein (Di19), zinc-binding Imm-NTF2-2 PF15631.1 KFM05765.1 - 0.00033 20.5 0.0 2.3 8.2 0.0 4.8 3 1 3 6 6 6 1 NTF2 fold immunity protein zf-RING_3 PF14369.1 KFM05765.1 - 0.012 15.5 50.6 0.4 10.7 0.2 10.5 12 0 0 12 12 11 0 zinc-finger zf-met PF12874.2 KFM05765.1 - 0.062 13.5 1.5 0.056 13.6 2.8 11.3 10 1 1 11 11 11 0 Zinc-finger of C2H2 type BolA PF01722.13 KFM05765.1 - 0.12 12.3 4.6 1.9 8.5 0.0 3.9 5 1 0 5 5 5 0 BolA-like protein IGPD PF00475.13 KFM05765.1 - 0.45 10.3 2.5 7.5 6.3 0.1 3.4 3 1 1 4 4 4 0 Imidazoleglycerol-phosphate dehydratase HTH_18 PF12833.2 KFM05765.1 - 0.56 10.3 4.0 71 3.6 0.0 4.8 6 1 0 6 6 6 0 Helix-turn-helix domain Flag1_repress PF03614.8 KFM05765.1 - 3.3 7.2 7.5 3.3 7.2 0.1 3.8 3 1 1 4 4 4 0 Repressor of phase-1 flagellin zf-CHCC PF10276.4 KFM05765.1 - 7.6 6.4 48.7 3 7.7 0.3 9.4 10 0 0 10 10 10 0 Zinc-finger domain zf-C2H2 PF00096.21 KFM05766.1 - 2.6e-27 93.4 88.6 0.00027 21.1 4.2 10.7 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM05766.1 - 1.4e-20 72.0 81.7 0.0022 18.1 2.5 10.8 10 0 0 10 10 10 10 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFM05766.1 - 7e-09 35.5 2.0 7e-09 35.5 1.4 13.6 14 1 0 14 14 14 3 Zinc-finger double domain zf-Di19 PF05605.7 KFM05766.1 - 1.7e-05 24.8 33.7 0.67 10.1 0.1 6.3 4 2 1 5 5 5 4 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 KFM05766.1 - 0.0016 18.5 0.4 0.0016 18.5 0.3 9.1 10 0 0 10 10 10 2 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.2 KFM05766.1 - 0.042 13.9 0.4 0.042 13.9 0.3 7.7 5 2 2 8 8 8 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 KFM05766.1 - 0.95 9.2 39.5 0.085 12.5 1.5 7.0 7 0 0 7 7 7 0 zinc-finger of a C2HC-type DUF629 PF04780.7 KFM05766.1 - 5.2 5.4 17.3 0.25 9.8 0.1 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.2 KFM05767.1 - 1.1e-12 47.8 20.5 0.0037 17.3 0.7 5.5 4 2 1 5 5 5 4 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 KFM05767.1 - 1.7e-09 37.4 29.0 0.069 13.5 1.0 5.6 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM05767.1 - 1.3e-07 31.4 19.8 0.058 13.7 1.6 5.4 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM05767.1 - 0.0001 22.0 25.8 0.13 12.1 0.4 5.7 6 0 0 6 6 6 4 C2H2-type zinc finger zf-met PF12874.2 KFM05767.1 - 0.0048 17.0 9.4 0.018 15.2 1.4 3.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type DUF678 PF05077.7 KFM05767.1 - 0.062 13.2 7.2 4.7 7.2 0.0 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF678) zf-C2HC_2 PF13913.1 KFM05767.1 - 0.066 12.9 0.2 0.066 12.9 0.1 1.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PyrI_C PF02748.10 KFM05767.1 - 0.1 12.0 1.6 1.7 8.1 0.1 3.2 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn-ribbon_8 PF09723.5 KFM05767.1 - 0.25 11.3 11.6 4.7 7.2 0.0 5.3 5 0 0 5 5 5 0 Zinc ribbon domain zf-C2H2_jaz PF12171.3 KFM05767.1 - 0.47 10.6 22.8 0.19 11.9 0.6 4.8 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding ADH_zinc_N PF00107.21 KFM05768.1 - 1e-28 99.4 0.0 1.7e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFM05768.1 - 1.2e-10 41.0 0.2 7.7e-08 32.0 0.0 3.1 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KFM05768.1 - 1.2e-08 35.8 0.0 1e-07 32.8 0.0 2.3 2 1 0 2 2 2 1 Zinc-binding dehydrogenase SPACA7 PF15307.1 KFM05769.1 - 0.095 12.8 1.0 0.21 11.7 0.0 2.2 3 0 0 3 3 3 0 Sperm acrosome-associated protein 7 PHB_acc_N PF07879.6 KFM05769.1 - 0.35 10.6 2.6 1.1 9.0 0.0 3.1 4 0 0 4 4 4 0 PHB/PHA accumulation regulator DNA-binding domain zf-H2C2_2 PF13465.1 KFM05770.1 - 8.5e-13 47.9 105.4 1.2e-05 25.3 0.5 15.3 15 1 1 16 16 16 9 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFM05770.1 - 0.0044 17.1 3.0 0.0044 17.1 2.1 13.9 15 1 1 16 16 16 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM05770.1 - 0.0053 16.9 2.5 0.0053 16.9 1.7 9.6 11 0 0 11 11 11 3 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 KFM05770.1 - 0.0097 16.2 1.7 0.0097 16.2 1.2 18.2 19 0 0 19 19 19 7 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 KFM05770.1 - 0.011 15.7 0.6 0.011 15.7 0.4 14.3 7 6 6 14 14 14 0 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.7 KFM05770.1 - 0.088 12.5 54.9 0.4 10.4 0.1 9.6 7 2 0 9 9 9 0 A-kinase anchoring protein 95 (AKAP95) Peptidase_M20 PF01546.23 KFM05771.1 - 1.6e-31 109.2 0.0 2.5e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KFM05771.1 - 5.9e-14 51.7 0.0 1.2e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KFM05771.1 - 0.061 13.0 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M28 Peptidase_M20 PF01546.23 KFM05772.1 - 7e-34 116.9 0.0 1.1e-33 116.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KFM05772.1 - 4.3e-17 61.8 0.0 1.5e-16 60.0 0.0 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain PIP49_C PF12260.3 KFM05773.1 - 4.7e-59 198.9 1.6 5.7e-59 198.7 0.5 1.6 2 0 0 2 2 2 1 Protein-kinase domain of FAM69 PIP49_N PF14875.1 KFM05773.1 - 7.9e-12 45.1 0.0 7.9e-12 45.1 0.0 1.5 2 0 0 2 2 2 1 N-term cysteine-rich ER, FAM69 Fiji_64_capsid PF05880.6 KFM05774.1 - 0.084 11.2 0.1 0.092 11.0 0.0 1.0 1 0 0 1 1 1 0 Fijivirus 64 kDa capsid protein Cyt-b5 PF00173.23 KFM05775.1 - 4.7e-08 32.7 0.0 7.2e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TIM21 PF08294.6 KFM05776.1 - 3.8e-49 166.0 0.2 4.5e-49 165.8 0.1 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 KFM05776.1 - 3.9e-07 29.5 0.0 9.5e-07 28.3 0.0 1.6 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 F-box-like PF12937.2 KFM05777.1 - 1.3e-09 37.5 0.0 2.9e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFM05777.1 - 3.7e-07 29.6 0.0 7.2e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 F-box domain Fucokinase PF07959.7 KFM05777.1 - 0.019 13.5 0.0 4.3 5.7 0.0 2.2 2 0 0 2 2 2 0 L-fucokinase DUF456 PF04306.8 KFM05778.1 - 0.078 13.0 4.3 0.12 12.4 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Gly-zipper_OmpA PF13436.1 KFM05778.1 - 0.36 10.5 6.1 0.56 9.8 4.2 1.2 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_YMGG PF13441.1 KFM05778.1 - 0.91 9.0 15.1 1.4 8.5 10.4 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.1 KFM05778.1 - 5.4 6.7 15.7 14 5.3 10.5 1.8 1 1 1 2 2 2 0 Glycine zipper FYVE PF01363.16 KFM05779.1 - 1.4e-18 66.5 7.3 2.7e-18 65.6 5.1 1.5 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 KFM05779.1 - 9.9e-13 48.2 0.2 1.6e-12 47.4 0.1 1.4 1 0 0 1 1 1 1 PH domain FYVE_2 PF02318.11 KFM05779.1 - 0.0034 17.2 9.0 0.0058 16.5 6.1 1.5 1 1 0 1 1 1 1 FYVE-type zinc finger PH_11 PF15413.1 KFM05779.1 - 0.093 12.9 0.1 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain PH_6 PF15406.1 KFM05779.1 - 0.095 12.7 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain RdgC PF04381.7 KFM05779.1 - 0.11 11.3 0.1 0.17 10.8 0.1 1.2 1 0 0 1 1 1 0 Putative exonuclease, RdgC OrfB_Zn_ribbon PF07282.6 KFM05779.1 - 1.5 8.5 7.0 3.2 7.4 4.8 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-DHHC PF01529.15 KFM05779.1 - 5 6.4 7.4 0.4 10.0 1.6 1.8 2 0 0 2 2 2 0 DHHC palmitoyltransferase UPF0086 PF01868.11 KFM05780.1 - 5e-21 74.1 2.2 6.5e-21 73.7 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function UPF0086 I-set PF07679.11 KFM05781.1 - 0.0056 16.5 0.0 0.0064 16.3 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.12 KFM05781.1 - 0.013 15.3 0.0 0.014 15.2 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin V-set domain UCR_TM PF02921.9 KFM05782.1 - 4.9e-24 84.3 2.5 7.1e-24 83.8 1.7 1.3 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 KFM05782.1 - 1.2e-16 60.0 0.3 3e-16 58.7 0.2 1.7 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain Oxidored_q6 PF01058.17 KFM05782.1 - 0.11 12.1 0.0 0.26 10.8 0.0 1.7 2 0 0 2 2 2 0 NADH ubiquinone oxidoreductase, 20 Kd subunit Beta_helix PF13229.1 KFM05783.1 - 7.3e-11 42.0 0.8 1.3e-10 41.2 0.6 1.4 1 0 0 1 1 1 1 Right handed beta helix region NosD PF05048.8 KFM05783.1 - 1.6e-08 34.0 0.1 3e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Pectate_lyase_3 PF12708.2 KFM05783.1 - 0.00034 20.7 0.1 0.076 13.1 0.1 2.5 1 1 1 2 2 2 2 Pectate lyase superfamily protein 7tm_1 PF00001.16 KFM05784.1 - 4e-61 206.4 6.7 5.2e-61 206.0 4.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM05784.1 - 1.3e-07 31.0 12.6 3.6e-05 23.0 3.1 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM05784.1 - 0.00012 21.2 8.0 0.00012 21.2 5.5 2.1 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Vps35 PF03635.12 KFM05785.1 - 0 1013.2 14.0 0 1013.0 9.7 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 FerA PF08165.6 KFM05785.1 - 0.015 14.9 0.1 0.066 12.8 0.0 2.2 1 0 0 1 1 1 0 FerA (NUC095) domain ORC6 PF05460.8 KFM05786.1 - 4.4e-11 42.4 11.8 1.4e-09 37.5 0.4 2.9 2 1 1 3 3 3 2 Origin recognition complex subunit 6 (ORC6) HTH_36 PF13730.1 KFM05786.1 - 0.054 13.6 0.4 0.22 11.6 0.0 2.2 3 0 0 3 3 3 0 Helix-turn-helix domain UPF0547 PF10571.4 KFM05787.1 - 0.00092 18.8 2.4 0.0015 18.2 1.7 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 GAGA_bind PF06217.7 KFM05787.1 - 0.14 12.0 4.1 0.16 11.9 2.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family G-7-MTase PF12803.2 KFM05787.1 - 0.17 10.9 2.3 0.58 9.2 1.1 1.7 1 1 1 2 2 2 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) DUF1510 PF07423.6 KFM05787.1 - 0.42 9.9 7.7 0.51 9.6 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RR_TM4-6 PF06459.7 KFM05787.1 - 1.3 8.8 6.7 1.4 8.7 4.7 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NPR3 PF03666.8 KFM05787.1 - 5.2 5.4 8.8 6 5.2 6.1 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Dsh_C PF12316.3 KFM05787.1 - 7.8 6.5 7.9 9.3 6.2 5.5 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Aminotran_1_2 PF00155.16 KFM05788.1 - 1.5e-31 109.6 0.0 1.8e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Borealin PF10512.4 KFM05789.1 - 1.6e-12 47.3 0.0 1.7e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Cell division cycle-associated protein 8 CTDII PF01556.13 KFM05790.1 - 2.3e-25 88.2 0.1 6.5e-23 80.4 0.0 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 KFM05790.1 - 4.5e-17 61.5 0.9 8.3e-17 60.6 0.6 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KFM05790.1 - 6.1e-16 58.2 17.7 1.1e-15 57.4 12.3 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 KFM05790.1 - 0.0016 18.0 8.4 0.041 13.5 1.4 2.3 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family DUF1258 PF06869.7 KFM05790.1 - 3 6.8 7.6 2.1 7.3 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1258) CUB PF00431.15 KFM05791.1 - 4.2e-42 142.6 0.2 3.2e-27 94.7 0.0 3.0 3 0 0 3 3 3 2 CUB domain Ldl_recept_a PF00057.13 KFM05791.1 - 3.1e-06 26.9 4.7 3.1e-06 26.9 3.2 2.5 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A VCBS PF13517.1 KFM05792.1 - 1.8e-14 53.8 16.4 1.8e-05 25.0 0.6 4.9 2 2 4 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 KFM05792.1 - 1.4e-12 46.9 4.2 0.14 11.9 0.0 6.1 6 0 0 6 6 6 4 FG-GAP repeat K1 PF02960.9 KFM05792.1 - 0.1 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 K1 glycoprotein Lon_C PF05362.8 KFM05793.1 - 2.4e-79 265.4 0.0 3.9e-79 264.7 0.0 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 KFM05793.1 - 8.3e-22 77.7 0.0 2.9e-21 76.0 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 KFM05793.1 - 1.8e-16 60.4 0.3 1.8e-16 60.4 0.2 2.0 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA_5 PF07728.9 KFM05793.1 - 6.4e-09 35.6 0.0 1.7e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KFM05793.1 - 2.9e-06 27.4 0.3 1.5e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain ChlI PF13541.1 KFM05793.1 - 9.1e-06 25.1 0.0 2.7e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_3 PF07726.6 KFM05793.1 - 0.00017 21.2 0.0 0.00041 19.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KFM05793.1 - 0.00071 20.3 0.0 0.0031 18.3 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_PrkA PF08298.6 KFM05793.1 - 0.0015 17.3 0.0 0.015 14.0 0.0 2.1 2 0 0 2 2 2 1 PrkA AAA domain AAA_2 PF07724.9 KFM05793.1 - 0.0017 18.2 0.0 0.0051 16.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 KFM05793.1 - 0.0034 16.1 0.2 0.8 8.3 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus DUF258 PF03193.11 KFM05793.1 - 0.0038 16.4 0.0 0.0087 15.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KFM05793.1 - 0.0038 17.3 0.0 0.035 14.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFM05793.1 - 0.0055 17.0 0.3 0.025 14.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KFM05793.1 - 0.012 14.7 0.0 0.04 12.9 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus SKI PF01202.17 KFM05793.1 - 0.013 15.4 0.0 0.042 13.7 0.0 1.9 1 0 0 1 1 1 0 Shikimate kinase AAA_33 PF13671.1 KFM05793.1 - 0.032 14.0 0.1 0.1 12.5 0.0 1.9 2 0 0 2 2 1 0 AAA domain MobB PF03205.9 KFM05793.1 - 0.037 13.7 0.1 0.15 11.7 0.0 2.1 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 KFM05793.1 - 0.039 13.3 0.2 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.1 KFM05793.1 - 0.061 12.8 3.1 0.14 11.7 0.3 2.5 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.1 KFM05793.1 - 0.067 13.0 0.0 0.62 9.9 0.0 2.5 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.17 KFM05793.1 - 0.12 12.5 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Birna_VP4 PF01768.11 KFM05793.1 - 0.14 11.1 0.1 0.29 10.1 0.0 1.5 1 0 0 1 1 1 0 Birnavirus VP4 protein Sina PF03145.11 KFM05794.1 - 4e-81 271.4 0.2 6.3e-81 270.7 0.1 1.3 1 0 0 1 1 1 1 Seven in absentia protein family RNase_Zc3h12a PF11977.3 KFM05795.1 - 7.3e-57 191.5 0.0 1.8e-56 190.2 0.0 1.7 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain DUF4392 PF14336.1 KFM05795.1 - 0.0011 17.9 0.1 0.0019 17.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4392) zf-C2H2 PF00096.21 KFM05796.1 - 7.1e-58 189.5 220.1 0.00022 21.3 0.8 30.8 31 0 0 31 31 31 27 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM05796.1 - 9.3e-50 163.3 203.4 0.0049 17.1 0.4 30.6 31 0 0 31 31 31 22 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFM05796.1 - 1.6e-40 135.4 197.0 4.9e-05 23.4 0.3 31.3 33 1 0 33 33 33 20 Zinc-finger double domain zf-Di19 PF05605.7 KFM05796.1 - 1.4e-24 85.9 188.3 8.9e-05 22.5 1.3 20.3 17 4 3 22 22 22 14 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 KFM05796.1 - 1.8e-20 72.0 165.6 2.2e-06 27.3 0.1 27.2 29 1 1 30 30 30 12 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM05796.1 - 3e-18 65.3 162.8 0.001 19.1 0.8 26.3 26 2 2 28 28 28 13 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFM05796.1 - 1.7e-05 24.8 174.6 0.3 11.2 3.3 24.9 7 5 10 20 20 20 7 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KFM05796.1 - 0.00092 19.3 8.0 0.0027 17.8 1.5 23.2 26 0 0 26 26 26 8 Zinc-finger of C2H2 type Tmemb_18A PF09771.4 KFM05798.1 - 3.6e-59 198.2 0.4 3.9e-59 198.1 0.2 1.0 1 0 0 1 1 1 1 Transmembrane protein 188 CopD PF05425.8 KFM05798.1 - 0.0036 17.4 0.1 0.0044 17.2 0.0 1.1 1 0 0 1 1 1 1 Copper resistance protein D DUF418 PF04235.7 KFM05798.1 - 0.047 13.3 0.3 0.05 13.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF418) HEAT_2 PF13646.1 KFM05799.1 - 4.2e-06 26.9 5.0 0.00086 19.5 0.0 4.2 4 1 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 KFM05799.1 - 1.1e-05 25.7 2.4 0.00043 20.6 0.3 4.1 3 2 1 4 4 4 2 HEAT-like repeat HEAT PF02985.17 KFM05799.1 - 0.00015 21.5 8.6 0.33 11.1 0.1 5.4 6 0 0 6 6 6 2 HEAT repeat Arm PF00514.18 KFM05799.1 - 0.00042 20.0 11.4 0.003 17.3 0.1 5.7 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat PAP_assoc PF03828.14 KFM05800.1 - 1.5e-15 56.8 0.1 4.8e-15 55.2 0.0 2.0 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KFM05800.1 - 7.1e-15 55.1 0.1 1.8e-14 53.7 0.1 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF3512 PF12024.3 KFM05801.1 - 1.3e-90 303.0 0.1 1.3e-90 303.0 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3512) Bromodomain PF00439.20 KFM05801.1 - 4.6e-22 77.7 1.6 9.7e-22 76.6 1.1 1.6 1 0 0 1 1 1 1 Bromodomain DUF2796 PF10986.3 KFM05801.1 - 2.3 8.1 9.2 0.053 13.4 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) EF-hand_6 PF13405.1 KFM05803.1 - 0.0016 18.1 0.0 0.0037 17.0 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain Nitroreductase PF00881.19 KFM05803.1 - 0.0063 16.3 0.4 0.086 12.6 0.0 2.3 2 1 0 2 2 2 1 Nitroreductase family EF-hand_1 PF00036.27 KFM05803.1 - 0.018 14.3 0.0 0.036 13.3 0.0 1.5 1 0 0 1 1 1 0 EF hand Ribosomal_L23 PF00276.15 KFM05803.1 - 0.02 14.8 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L23 EF-hand_7 PF13499.1 KFM05803.1 - 0.023 14.8 0.1 0.071 13.2 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair PX PF00787.19 KFM05805.1 - 9.1e-17 60.8 5.9 3.5e-16 58.9 2.9 2.6 3 0 0 3 3 3 1 PX domain TPR_12 PF13424.1 KFM05805.1 - 0.001 18.9 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat Ocnus PF05005.10 KFM05805.1 - 0.0051 16.6 0.0 0.0093 15.8 0.0 1.4 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) TPR_11 PF13414.1 KFM05805.1 - 0.056 13.0 0.0 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 TPR repeat zf-C2H2 PF00096.21 KFM05806.1 - 1.7e-33 112.9 74.5 4.6e-05 23.5 0.1 10.6 10 0 0 10 10 10 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM05806.1 - 4.5e-32 107.9 65.2 0.00011 22.2 0.4 10.5 10 0 0 10 10 10 8 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFM05806.1 - 1.4e-29 100.8 73.9 4e-08 33.1 0.7 12.0 13 0 0 13 13 12 6 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFM05806.1 - 1.1e-27 95.4 42.5 0.00011 22.1 1.2 9.5 9 0 0 9 9 9 8 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM05806.1 - 3.8e-26 90.4 53.0 0.00057 20.0 0.4 9.8 9 0 0 9 9 9 8 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFM05806.1 - 6e-08 32.3 56.2 0.047 13.6 1.1 9.5 9 0 0 9 9 9 5 C2H2-type zinc finger IZUMO PF15005.1 KFM05806.1 - 0.00032 20.7 1.2 0.029 14.4 0.1 2.5 2 0 0 2 2 2 1 Izumo sperm-egg fusion zf-C2HC_2 PF13913.1 KFM05806.1 - 0.01 15.5 39.0 1.1 8.9 0.1 8.0 8 0 0 8 8 8 0 zinc-finger of a C2HC-type BolA PF01722.13 KFM05806.1 - 0.014 15.3 6.1 4.5 7.3 0.0 5.0 5 0 0 5 5 5 0 BolA-like protein zf-C2H2_2 PF12756.2 KFM05806.1 - 0.034 14.2 46.3 1.2 9.2 0.7 9.1 5 4 5 10 10 10 0 C2H2 type zinc-finger (2 copies) Imm-NTF2-2 PF15631.1 KFM05806.1 - 0.15 12.0 0.0 1.4e+02 2.5 0.0 3.9 4 0 0 4 4 4 0 NTF2 fold immunity protein Elf1 PF05129.8 KFM05806.1 - 2.1 8.1 29.5 0.87 9.3 0.8 5.6 4 1 1 5 5 5 0 Transcription elongation factor Elf1 like Rad50_zn_hook PF04423.9 KFM05806.1 - 6.8 6.2 10.4 7.5 6.1 0.0 5.0 5 0 0 5 5 5 0 Rad50 zinc hook motif HMG_box PF00505.14 KFM05807.1 - 4.1e-18 65.3 0.6 1.1e-17 64.0 0.4 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFM05807.1 - 5.1e-12 45.9 1.0 5.1e-12 45.9 0.7 2.2 2 1 1 3 3 3 1 HMG-box domain RB_A PF01858.12 KFM05808.1 - 1.4e-77 259.8 1.7 1.6e-77 259.6 0.2 1.9 2 0 0 2 2 2 1 Retinoblastoma-associated protein A domain RB_B PF01857.15 KFM05808.1 - 7.6e-60 200.2 0.1 4.7e-59 197.7 0.1 2.5 1 1 0 1 1 1 1 Retinoblastoma-associated protein B domain DUF3452 PF11934.3 KFM05808.1 - 1.1e-44 151.0 0.1 3.8e-44 149.3 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3452) Imm-NTF2 PF15655.1 KFM05808.1 - 0.24 11.8 2.7 0.21 12.0 0.2 2.1 2 0 0 2 2 2 0 NTF2 fold immunity protein UQ_con PF00179.21 KFM05810.1 - 7.1e-22 77.3 0.0 1.2e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF3250 PF11618.3 KFM05811.1 - 1.4e-42 144.2 6.2 6.6e-36 122.7 0.3 4.0 4 0 0 4 4 4 2 Protein of unknown function (DUF3250) C2 PF00168.25 KFM05811.1 - 3.4e-05 23.6 0.0 8.6e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 C2 domain FTO_NTD PF12933.2 KFM05812.1 - 1.5e-100 335.5 0.1 2.3e-100 334.9 0.1 1.3 1 0 0 1 1 1 1 FTO catalytic domain FTO_CTD PF12934.2 KFM05812.1 - 5.4e-47 159.5 7.1 1e-46 158.6 4.9 1.5 1 0 0 1 1 1 1 FTO C-terminal domain FTO_CTD PF12934.2 KFM05813.1 - 2.9e-14 53.0 0.2 3.1e-14 52.9 0.2 1.0 1 0 0 1 1 1 1 FTO C-terminal domain Ribosomal_L31 PF01197.13 KFM05813.1 - 0.15 12.1 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L31 Homeobox_KN PF05920.6 KFM05814.1 - 5.1e-16 58.0 0.3 8.5e-16 57.3 0.2 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KFM05814.1 - 7.5e-09 35.0 0.4 9.1e-09 34.8 0.3 1.1 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 KFM05814.1 - 0.0045 16.0 0.1 0.0092 15.0 0.0 1.6 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez HA PF03457.9 KFM05814.1 - 0.016 15.2 0.1 0.028 14.5 0.0 1.4 1 1 0 1 1 1 0 Helicase associated domain MRP-S32 PF10210.4 KFM05814.1 - 0.05 13.9 1.1 0.06 13.6 0.8 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 Homeobox_KN PF05920.6 KFM05816.1 - 1.7e-16 59.6 0.2 2.8e-16 58.9 0.1 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KFM05816.1 - 5.6e-09 35.4 1.9 6.8e-09 35.2 1.3 1.1 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 KFM05816.1 - 0.0052 15.8 0.1 0.0092 15.0 0.0 1.5 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez MRP-S32 PF10210.4 KFM05816.1 - 0.13 12.6 2.0 0.14 12.5 1.4 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 Phage_P2_GpE PF06528.7 KFM05816.1 - 0.14 11.6 0.1 0.27 10.7 0.1 1.5 1 0 0 1 1 1 0 Phage P2 GpE Peptidase_M10 PF00413.19 KFM05818.1 - 1.2e-65 219.9 0.2 1.2e-64 216.7 0.1 2.2 1 1 0 1 1 1 1 Matrixin fn2 PF00040.14 KFM05818.1 - 4.8e-56 186.4 36.8 4.5e-19 68.1 2.5 3.7 3 0 0 3 3 3 3 Fibronectin type II domain Hemopexin PF00045.14 KFM05818.1 - 2.8e-41 138.9 8.6 6.6e-12 44.9 0.2 4.6 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.13 KFM05818.1 - 3.9e-09 36.3 0.0 9.1e-09 35.1 0.0 1.7 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Reprolysin_3 PF13582.1 KFM05818.1 - 0.0094 16.4 0.1 0.069 13.6 0.0 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.19 KFM05818.1 - 0.012 15.0 0.0 4.7 6.5 0.0 2.6 3 0 0 3 3 3 0 Astacin (Peptidase family M12A) Reprolysin_5 PF13688.1 KFM05818.1 - 0.043 13.7 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 DUF3152 PF11350.3 KFM05818.1 - 0.11 11.9 0.0 0.79 9.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3152) Reprolysin_2 PF13574.1 KFM05818.1 - 0.17 11.8 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like EF-hand_1 PF00036.27 KFM05819.1 - 3e-19 66.7 11.9 4.7e-06 25.5 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 KFM05819.1 - 3.6e-17 60.6 7.2 2.2e-05 23.9 0.1 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 KFM05819.1 - 2.5e-15 55.8 11.6 2.8e-08 33.2 0.7 4.1 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 KFM05819.1 - 6.6e-15 53.6 13.8 9.2e-05 21.6 0.2 4.0 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 KFM05819.1 - 7.7e-15 54.7 6.1 7.1e-09 35.6 1.5 3.4 2 1 1 3 3 3 2 EF-hand domain pair Acyltransferase PF01553.16 KFM05819.1 - 3.7e-14 52.2 0.0 6.2e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase EF-hand_4 PF12763.2 KFM05819.1 - 0.0012 18.5 3.9 0.51 10.0 0.0 3.4 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KFM05819.1 - 0.096 12.7 0.1 0.72 9.9 0.1 2.2 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region SNF PF00209.13 KFM05820.1 - 2.6e-238 791.7 33.4 2.9e-238 791.5 23.2 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family AA_permease PF00324.16 KFM05821.1 - 5.2e-60 203.1 32.9 6.3e-35 120.4 4.8 2.1 2 0 0 2 2 2 2 Amino acid permease KCl_Cotrans_1 PF03522.10 KFM05821.1 - 3.2e-12 45.7 0.1 7.1e-12 44.6 0.1 1.6 1 0 0 1 1 1 1 K-Cl Co-transporter type 1 (KCC1) Peptidase_M19 PF01244.16 KFM05822.1 - 4.4e-105 351.1 0.0 5e-105 350.9 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) 7tm_1 PF00001.16 KFM05823.1 - 1.4e-59 201.2 15.9 1.7e-59 201.0 11.0 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 KFM05823.1 - 5e-08 32.4 12.9 6.9e-08 31.9 8.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.4 KFM05823.1 - 8.4e-08 31.6 14.4 1.4e-06 27.6 10.0 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.4 KFM05823.1 - 8.9e-06 25.0 13.8 1.2e-05 24.5 9.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM05823.1 - 0.00028 20.0 15.4 0.00078 18.6 10.7 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srb PF02175.11 KFM05823.1 - 0.0076 15.8 7.0 0.019 14.5 4.8 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srb 7TM_GPCR_Srd PF10317.4 KFM05823.1 - 0.073 12.0 19.6 0.46 9.4 13.6 2.0 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd DUF420 PF04238.7 KFM05823.1 - 4.5 7.2 15.8 0.076 12.9 1.4 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF420) RHD PF00554.17 KFM05824.1 - 6.8e-25 87.7 1.1 4.3e-22 78.6 0.1 3.6 3 1 0 3 3 3 2 Rel homology domain (RHD) TIG PF01833.19 KFM05824.1 - 2.7e-05 24.0 0.1 0.00019 21.3 0.1 2.6 1 1 0 1 1 1 1 IPT/TIG domain RRM_6 PF14259.1 KFM05825.1 - 1.8e-49 165.5 0.0 7e-17 61.1 0.0 4.4 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFM05825.1 - 8.6e-14 50.9 0.0 0.002 17.6 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM05825.1 - 0.00013 21.7 0.3 3 7.7 0.1 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 KFM05825.1 - 0.008 16.4 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 Exonuclease DUF4049 PF13258.1 KFM05825.1 - 0.17 10.8 0.0 0.42 9.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) 7tm_1 PF00001.16 KFM05826.1 - 6.4e-48 163.1 24.7 1.1e-47 162.4 17.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM05826.1 - 2.4e-08 33.4 27.2 2.4e-08 33.4 18.9 1.6 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM05826.1 - 0.00018 20.7 17.4 0.00018 20.7 12.0 2.4 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx His_kinase PF06580.8 KFM05826.1 - 0.051 13.4 0.1 0.15 11.9 0.1 1.8 1 0 0 1 1 1 0 Histidine kinase DUF962 PF06127.6 KFM05826.1 - 0.75 9.7 4.5 24 4.9 3.1 2.9 1 1 0 1 1 1 0 Protein of unknown function (DUF962) LCAT PF02450.10 KFM05827.1 - 2.9e-82 276.6 0.4 3.7e-82 276.3 0.2 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF915 PF06028.6 KFM05827.1 - 7.5e-06 25.2 0.4 0.016 14.2 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_6 PF12697.2 KFM05827.1 - 0.00073 19.4 0.0 0.00088 19.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KFM05827.1 - 0.043 13.4 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF900 PF05990.7 KFM05827.1 - 0.1 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.2 KFM05827.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Exo_endo_phos PF03372.18 KFM05828.1 - 2.6e-08 34.0 0.0 4.4e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SCPU PF05229.10 KFM05828.1 - 0.017 15.1 0.8 0.84 9.7 0.0 2.5 2 0 0 2 2 2 0 Spore Coat Protein U domain CBM_6 PF03422.10 KFM05828.1 - 0.03 14.4 0.2 0.083 13.0 0.1 1.8 1 0 0 1 1 1 0 Carbohydrate binding module (family 6) PrmA PF06325.8 KFM05829.1 - 7.6e-06 25.2 0.1 1.7e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 KFM05829.1 - 4.4e-05 24.0 0.0 0.00011 22.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFM05829.1 - 0.0012 18.8 0.0 0.0053 16.7 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFM05829.1 - 0.0034 17.1 0.0 0.0066 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cas_Cas02710 PF09670.5 KFM05829.1 - 0.0059 15.2 0.1 0.0093 14.6 0.1 1.2 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Cas02710) Methyltransf_4 PF02390.12 KFM05829.1 - 0.0083 15.1 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase YMF19 PF02326.10 KFM05829.1 - 0.021 15.3 0.3 0.054 14.0 0.2 1.7 1 0 0 1 1 1 0 Plant ATP synthase F0 MTS PF05175.9 KFM05829.1 - 0.029 13.7 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.1 KFM05829.1 - 0.033 13.7 0.2 0.23 11.0 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Cons_hypoth95 PF03602.10 KFM05829.1 - 0.077 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DUF1762 PF08574.5 KFM05830.1 - 2.3e-05 24.7 21.7 2.3e-05 24.7 15.0 3.2 3 1 0 3 3 3 1 Protein of unknown function (DUF1762) AA_permease_2 PF13520.1 KFM05831.1 - 2.5e-65 220.7 41.4 3e-65 220.4 28.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFM05831.1 - 6.5e-23 80.8 32.7 6.5e-23 80.8 22.7 1.4 1 1 0 1 1 1 1 Amino acid permease Pkinase PF00069.20 KFM05832.1 - 2.5e-28 98.9 0.0 3.1e-28 98.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM05832.1 - 1e-25 90.2 0.0 1.2e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFM05832.1 - 0.02 14.6 0.2 0.16 11.7 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pyr_redox_3 PF13738.1 KFM05833.1 - 5e-12 46.3 0.0 8.8e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFM05833.1 - 3.9e-05 23.6 0.0 8.7e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fcf2 PF08698.6 KFM05833.1 - 0.14 12.1 0.2 0.26 11.3 0.1 1.4 1 0 0 1 1 1 0 Fcf2 pre-rRNA processing EF-hand_8 PF13833.1 KFM05834.1 - 6.3e-06 25.7 2.1 8.2e-05 22.1 1.4 2.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KFM05834.1 - 2.8e-05 23.0 1.7 0.022 14.0 0.1 2.9 1 1 2 3 3 3 3 EF hand EF-hand_6 PF13405.1 KFM05834.1 - 4.4e-05 23.0 0.8 0.049 13.5 0.1 2.7 1 1 1 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 KFM05834.1 - 0.00024 21.1 1.8 0.00075 19.5 1.3 1.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 KFM05834.1 - 0.0014 17.8 3.1 0.39 10.1 0.0 3.2 1 1 2 3 3 3 2 EF hand SICA_beta PF12878.2 KFM05834.1 - 0.12 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 SICA extracellular beta domain Aa_trans PF01490.13 KFM05835.1 - 2e-33 115.5 4.6 2.5e-33 115.1 3.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 KFM05835.1 - 3.6e-05 22.4 5.1 4.7e-05 22.1 3.5 1.1 1 0 0 1 1 1 1 Amino acid permease Spore_permease PF03845.8 KFM05835.1 - 0.0075 14.9 1.3 0.0075 14.9 0.9 2.2 2 0 0 2 2 2 1 Spore germination protein NrfD_2 PF14589.1 KFM05835.1 - 0.026 14.1 0.6 0.026 14.1 0.4 1.6 2 0 0 2 2 2 0 Polysulfide reductase Lysis_S PF04971.7 KFM05835.1 - 0.54 9.9 3.1 4.9 6.9 0.7 2.7 1 1 1 2 2 2 0 Lysis protein S Peptidase_S8 PF00082.17 KFM05836.1 - 3.4e-43 147.8 0.0 4.8e-43 147.3 0.0 1.2 1 0 0 1 1 1 1 Subtilase family adh_short PF00106.20 KFM05837.1 - 9.8e-26 90.6 0.0 1.5e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFM05837.1 - 1.7e-10 41.0 0.1 2.3e-10 40.6 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFM05837.1 - 4.3e-06 26.5 0.0 9.5e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KFM05837.1 - 0.00013 22.0 0.0 0.00024 21.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KFM05837.1 - 0.00045 19.1 0.2 0.0026 16.7 0.1 2.1 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 KFM05837.1 - 0.0054 15.7 0.0 0.011 14.7 0.0 1.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase Epimerase PF01370.16 KFM05837.1 - 0.026 13.9 0.6 0.27 10.6 0.4 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ApbA PF02558.11 KFM05837.1 - 0.073 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA LRR_8 PF13855.1 KFM05838.1 - 8.9e-18 63.7 29.4 1.7e-08 34.0 3.2 3.3 2 1 3 5 5 5 3 Leucine rich repeat LRR_4 PF12799.2 KFM05838.1 - 2.2e-16 59.0 23.9 5.1e-07 29.1 0.5 4.3 3 1 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 KFM05838.1 - 2.7e-07 30.3 4.6 4e-07 29.7 2.4 1.7 1 1 1 2 2 2 1 Leucine-rich repeat LRR_6 PF13516.1 KFM05838.1 - 2.7e-05 23.7 17.1 0.0078 16.1 0.1 5.9 4 2 1 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.28 KFM05838.1 - 0.00037 20.1 21.2 1.6 9.0 1.3 6.2 5 1 0 5 5 5 4 Leucine Rich Repeat LRR_7 PF13504.1 KFM05838.1 - 0.00041 20.0 12.6 29 5.4 0.0 6.7 4 2 2 6 6 6 0 Leucine rich repeat HSF_DNA-bind PF00447.12 KFM05839.1 - 7.1e-36 122.5 0.2 1.4e-35 121.5 0.1 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Vert_HS_TF PF06546.6 KFM05839.1 - 8.5e-20 71.2 0.1 1.3e-19 70.6 0.1 1.2 1 0 0 1 1 1 1 Vertebrate heat shock transcription factor DUF904 PF06005.7 KFM05839.1 - 2.5 8.4 10.0 7.5 6.9 6.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF904) TRADD_N PF09034.5 KFM05840.1 - 7.4e-42 141.8 3.2 1.2e-41 141.1 2.2 1.4 1 0 0 1 1 1 1 TRADD, N-terminal domain Death PF00531.17 KFM05840.1 - 3.3e-10 39.5 1.3 5.7e-10 38.8 0.2 1.9 2 0 0 2 2 2 1 Death domain MarR PF01047.17 KFM05840.1 - 0.094 12.4 0.2 0.64 9.7 0.0 2.3 3 0 0 3 3 3 0 MarR family UPF0183 PF03676.9 KFM05841.1 - 4.6e-185 614.8 0.4 5.3e-185 614.6 0.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) CBF_beta PF02312.12 KFM05842.1 - 1.2e-46 158.4 0.1 1.3e-46 158.3 0.0 1.0 1 0 0 1 1 1 1 Core binding factor beta subunit G-alpha PF00503.15 KFM05843.1 - 7.2e-117 390.3 3.4 8.1e-117 390.1 2.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KFM05843.1 - 2.9e-13 49.4 0.0 6.8e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFM05843.1 - 0.00063 18.9 0.1 0.0013 17.9 0.1 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region zf-RING_2 PF13639.1 KFM05844.1 - 5.3e-15 54.9 8.8 7.6e-15 54.4 4.4 2.3 2 0 0 2 2 2 1 Ring finger domain CUE PF02845.11 KFM05844.1 - 3.6e-10 39.1 0.1 7.7e-10 38.0 0.1 1.6 1 0 0 1 1 1 1 CUE domain zf-C3HC4_3 PF13920.1 KFM05844.1 - 1.4e-09 37.4 3.3 3.1e-09 36.3 2.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM05844.1 - 5e-09 36.0 5.7 1.5e-08 34.5 4.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM05844.1 - 3.7e-08 32.8 5.2 7.3e-08 31.9 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFM05844.1 - 3.9e-08 33.2 8.4 2.7e-07 30.6 5.1 2.7 2 1 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KFM05844.1 - 2.9e-06 26.8 3.8 6.1e-06 25.8 2.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KFM05844.1 - 2.3e-05 24.1 0.6 7.3e-05 22.5 0.4 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 KFM05844.1 - 0.0011 18.8 4.4 0.0021 17.8 3.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KFM05844.1 - 0.002 17.7 4.5 0.0059 16.2 3.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Cas_Csy4 PF09618.5 KFM05844.1 - 0.089 12.5 0.6 0.17 11.7 0.4 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) RINGv PF12906.2 KFM05844.1 - 0.24 11.4 7.7 0.56 10.2 5.3 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.1 KFM05844.1 - 0.32 10.5 2.4 1 9.0 1.7 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 KFM05844.1 - 0.39 10.7 5.6 1.2 9.1 3.9 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain NUDIX_2 PF13869.1 KFM05845.1 - 8.8e-80 266.4 0.0 9.8e-80 266.3 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase NUDIX PF00293.23 KFM05845.1 - 0.01 15.5 0.0 0.016 14.8 0.0 1.4 1 1 0 1 1 1 0 NUDIX domain Ofd1_CTDD PF10637.4 KFM05846.1 - 4e-51 173.7 0.0 5.7e-46 156.7 0.0 2.3 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 KFM05846.1 - 1.8e-14 54.0 0.1 1.3e-12 48.1 0.0 2.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily BBS2_C PF14782.1 KFM05847.1 - 5.1e-189 628.3 0.1 4.3e-187 621.9 0.0 2.1 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid PF14783.1 KFM05847.1 - 4.9e-48 161.5 0.0 4.4e-46 155.2 0.0 2.7 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region BBS2_N PF14781.1 KFM05847.1 - 2.9e-44 149.9 0.0 8.3e-44 148.5 0.0 1.9 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, N-terminal FG-GAP PF01839.18 KFM05847.1 - 2.5e-06 27.0 0.0 0.00026 20.5 0.0 2.6 2 0 0 2 2 2 1 FG-GAP repeat VCBS PF13517.1 KFM05847.1 - 2e-05 24.8 2.1 0.035 14.4 0.4 3.5 3 1 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF2935 PF11155.3 KFM05847.1 - 0.045 13.8 0.8 0.28 11.2 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) Metallothio PF00131.15 KFM05848.1 - 9.8e-14 50.9 63.2 1.1e-13 50.8 43.8 1.0 1 0 0 1 1 1 1 Metallothionein Nic96 PF04097.9 KFM05849.1 - 7.2e-197 655.2 0.2 8.7e-197 655.0 0.2 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Apc3 PF12895.2 KFM05849.1 - 0.6 10.2 6.6 0.54 10.4 0.3 3.7 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 AA_permease PF00324.16 KFM05850.1 - 1.9e-132 442.0 36.4 2.5e-132 441.6 25.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_N PF08403.5 KFM05850.1 - 2.2e-15 55.7 0.0 4e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Amino acid permease N-terminal Tmemb_170 PF10190.4 KFM05851.1 - 4e-47 158.5 6.1 5e-47 158.2 4.2 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 DUF2781 PF10914.3 KFM05851.1 - 0.18 11.6 3.5 0.53 10.0 2.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2781) DUF2516 PF10724.4 KFM05851.1 - 0.31 11.0 2.4 0.27 11.2 0.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2516) BCNT PF07572.7 KFM05852.1 - 1.1e-28 98.9 0.5 1.1e-28 98.9 0.3 3.0 3 1 0 3 3 3 1 Bucentaur or craniofacial development DUF572 PF04502.8 KFM05852.1 - 4.1 6.5 30.7 19 4.3 16.8 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF572) Sec7 PF01369.15 KFM05853.1 - 1.3e-70 236.9 0.1 2e-70 236.3 0.1 1.2 1 0 0 1 1 1 1 Sec7 domain PH PF00169.24 KFM05853.1 - 2.2e-25 88.8 0.0 4e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KFM05853.1 - 3e-07 30.6 0.6 1.8e-06 28.1 0.4 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain BBS2_C PF14782.1 KFM05853.1 - 0.0015 17.1 1.4 0.12 10.9 0.7 2.1 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, C-terminal PH_3 PF14593.1 KFM05853.1 - 0.0024 17.7 0.2 0.015 15.1 0.1 2.2 1 1 0 1 1 1 1 PH domain PH_8 PF15409.1 KFM05853.1 - 0.017 15.1 0.0 0.09 12.8 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain DASH_Spc34 PF08657.5 KFM05853.1 - 0.036 13.7 1.4 0.065 12.8 1.0 1.3 1 0 0 1 1 1 0 DASH complex subunit Spc34 DUF342 PF03961.8 KFM05853.1 - 0.048 12.0 0.8 0.063 11.6 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 KFM05853.1 - 0.12 11.4 3.2 0.19 10.7 2.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 TMF_DNA_bd PF12329.3 KFM05853.1 - 0.2 11.4 5.8 1.5 8.6 3.1 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 KFM05853.1 - 0.24 10.9 1.9 0.52 9.8 1.3 1.5 1 0 0 1 1 1 0 Septum formation initiator IncA PF04156.9 KFM05853.1 - 0.26 10.8 1.6 0.43 10.1 1.1 1.3 1 0 0 1 1 1 0 IncA protein Fzo_mitofusin PF04799.8 KFM05853.1 - 0.3 10.4 1.8 0.6 9.4 1.2 1.4 1 0 0 1 1 1 0 fzo-like conserved region Fer4_15 PF13459.1 KFM05854.1 - 0.049 14.2 0.0 0.083 13.4 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain DUF4519 PF15012.1 KFM05854.1 - 0.59 10.0 4.0 0.83 9.6 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) TIMP PF00965.12 KFM05855.1 - 1.9e-56 190.5 2.7 2.1e-56 190.3 1.9 1.0 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase NTR PF01759.16 KFM05855.1 - 0.028 13.9 0.2 0.065 12.8 0.0 1.7 1 1 1 2 2 2 0 UNC-6/NTR/C345C module Apyrase PF06079.6 KFM05856.1 - 4.1e-85 285.4 0.3 4.8e-85 285.2 0.2 1.0 1 0 0 1 1 1 1 Apyrase C1q PF00386.16 KFM05857.1 - 4.9e-37 126.7 1.0 6.2e-37 126.4 0.7 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 KFM05857.1 - 1.5e-08 34.0 13.1 2.2e-08 33.5 9.1 1.1 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Glyco_hydro_85 PF03644.8 KFM05858.1 - 3.3e-102 341.7 0.1 4.3e-102 341.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Fox-1_C PF12414.3 KFM05859.1 - 2e-39 133.8 23.7 4.6e-39 132.7 15.1 2.1 2 0 0 2 2 2 1 Calcitonin gene-related peptide regulator C terminal RRM_1 PF00076.17 KFM05859.1 - 1.6e-19 69.2 1.0 2.6e-19 68.6 0.1 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM05859.1 - 3.4e-15 55.7 0.1 5.6e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM05859.1 - 1.3e-10 40.9 0.1 2.8e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFM05859.1 - 0.028 14.2 0.1 0.054 13.3 0.0 1.5 1 1 0 1 1 1 0 RNA binding motif Chromo PF00385.19 KFM05861.1 - 1.2e-11 44.0 0.7 1.2e-11 44.0 0.5 1.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain VirC1 PF07015.6 KFM05861.1 - 0.24 10.4 0.2 0.37 9.8 0.2 1.2 1 0 0 1 1 1 0 VirC1 protein RabGAP-TBC PF00566.13 KFM05863.1 - 1.2e-46 158.9 1.5 1.2e-46 158.9 1.0 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 KFM05863.1 - 0.00024 20.4 0.2 0.14 11.4 0.4 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF3548) BRE1 PF08647.6 KFM05864.1 - 6e-15 54.9 17.2 6e-15 54.9 11.9 11.2 5 3 7 13 13 13 2 BRE1 E3 ubiquitin ligase Reo_sigmaC PF04582.7 KFM05864.1 - 0.24 10.5 28.7 0.27 10.3 0.1 5.6 2 1 1 5 5 5 0 Reovirus sigma C capsid protein Sulfatase PF00884.18 KFM05865.1 - 1.9e-46 158.6 0.0 5.2e-46 157.2 0.0 1.7 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KFM05865.1 - 1.3e-07 31.2 0.0 2.6e-06 27.0 0.0 2.7 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 KFM05865.1 - 0.03 14.6 0.3 0.063 13.5 0.2 1.6 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase UPF0239 PF06783.6 KFM05866.1 - 2.8 7.9 4.4 4 7.4 2.8 1.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) Endonuclease_5 PF04493.9 KFM05867.1 - 6.6e-57 192.1 0.0 7.7e-57 191.9 0.0 1.0 1 0 0 1 1 1 1 Endonuclease V Pentaxin PF00354.12 KFM05868.1 - 2.4e-17 63.0 0.0 2.8e-17 62.8 0.0 1.0 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.1 KFM05868.1 - 9e-11 42.2 0.0 1e-10 42.0 0.0 1.1 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.19 KFM05868.1 - 0.023 14.7 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 Laminin G domain Raptor_N PF14538.1 KFM05869.1 - 4.9e-75 250.5 0.0 9.9e-75 249.5 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT PF02985.17 KFM05869.1 - 2.1e-15 55.3 1.7 0.00019 21.2 0.0 6.1 5 0 0 5 5 5 3 HEAT repeat WD40 PF00400.27 KFM05869.1 - 1.9e-11 43.3 15.3 0.0056 16.5 0.1 7.7 9 0 0 9 9 9 3 WD domain, G-beta repeat HEAT_2 PF13646.1 KFM05869.1 - 4.4e-11 42.9 0.5 5.9e-06 26.4 0.0 4.1 3 1 1 4 4 4 2 HEAT repeats Cnd1 PF12717.2 KFM05869.1 - 2.7e-06 27.3 0.4 0.1 12.4 0.0 3.8 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 KFM05869.1 - 1.2e-05 25.6 0.6 0.12 12.8 0.0 4.2 4 0 0 4 4 4 2 HEAT-like repeat Arm PF00514.18 KFM05869.1 - 0.01 15.6 0.1 0.18 11.6 0.0 2.7 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat DUF2435 PF10363.4 KFM05869.1 - 0.011 15.5 0.0 0.95 9.4 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2435) Adaptin_N PF01602.15 KFM05869.1 - 0.21 9.8 0.0 0.83 7.8 0.0 1.8 1 1 0 1 1 1 0 Adaptin N terminal region Snf7 PF03357.16 KFM05870.1 - 3.1e-37 127.5 16.3 3.6e-37 127.3 11.3 1.0 1 0 0 1 1 1 1 Snf7 IMD PF08397.6 KFM05871.1 - 3.2e-94 314.2 6.6 4.2e-94 313.9 4.6 1.1 1 0 0 1 1 1 1 IRSp53/MIM homology domain SH3_9 PF14604.1 KFM05871.1 - 4.1e-10 39.0 0.0 7.3e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFM05871.1 - 7.5e-08 31.7 0.0 1.3e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM05871.1 - 1.1e-05 24.7 0.0 2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Exonuc_VII_L PF02601.10 KFM05871.1 - 1.1 8.3 6.0 1.5 7.9 4.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit PBP1_TM PF14812.1 KFM05872.1 - 7.4 6.9 6.2 15 6.0 0.7 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ENTH PF01417.15 KFM05874.1 - 0.024 14.5 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 ENTH domain DUF1685 PF07939.6 KFM05874.1 - 0.42 10.2 3.4 2.1 8.0 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1685) HEAT PF02985.17 KFM05874.1 - 0.99 9.6 3.0 1.4 9.1 0.1 2.7 3 0 0 3 3 3 0 HEAT repeat Hormone_recep PF00104.25 KFM05875.1 - 3.3e-36 124.3 0.3 4.7e-36 123.8 0.2 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFM05875.1 - 5.5e-31 106.6 12.3 1.1e-30 105.6 8.5 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) GAT PF03127.9 KFM05875.1 - 0.1 12.5 1.1 6.4 6.8 0.1 2.4 2 0 0 2 2 2 0 GAT domain G-patch PF01585.18 KFM05876.1 - 4.1e-17 61.6 1.7 7.7e-17 60.8 1.2 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KFM05876.1 - 3e-08 33.4 0.2 3e-08 33.4 0.1 2.7 3 0 0 3 3 3 1 DExH-box splicing factor binding site IQ PF00612.22 KFM05877.1 - 2.5e-08 32.8 24.3 2.8e-05 23.3 1.6 4.1 4 0 0 4 4 4 3 IQ calmodulin-binding motif Rrp15p PF07890.7 KFM05878.1 - 8e-41 139.1 14.6 1.4e-40 138.3 10.1 1.4 1 0 0 1 1 1 1 Rrp15p PRTP PF01366.13 KFM05878.1 - 1.1 7.1 5.5 1.6 6.6 3.8 1.2 1 0 0 1 1 1 0 Herpesvirus processing and transport protein TGFb_propeptide PF00688.13 KFM05879.1 - 1.3e-36 126.1 0.1 2e-36 125.5 0.0 1.2 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.15 KFM05879.1 - 5.9e-31 106.8 2.1 1.6e-30 105.4 1.4 1.8 1 0 0 1 1 1 1 Transforming growth factor beta like domain Abhydrolase_2 PF02230.11 KFM05880.1 - 3.8e-38 131.1 0.0 4.1e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KFM05880.1 - 5.6e-11 42.3 0.0 6e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KFM05880.1 - 3.6e-07 29.9 0.0 0.00039 20.0 0.0 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFM05880.1 - 1e-06 28.1 0.6 0.00027 20.2 0.0 2.1 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KFM05880.1 - 2e-05 24.5 0.0 8.2e-05 22.5 0.0 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.13 KFM05880.1 - 5.8e-05 22.4 0.0 7e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.15 KFM05880.1 - 0.00091 18.7 0.0 0.00097 18.6 0.0 1.1 1 0 0 1 1 1 1 Putative esterase Lipase_3 PF01764.20 KFM05880.1 - 0.0016 18.0 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.15 KFM05880.1 - 0.0047 16.5 0.0 0.0058 16.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cation_efflux PF01545.16 KFM05881.1 - 4.1e-69 232.8 0.1 4.7e-69 232.6 0.1 1.0 1 0 0 1 1 1 1 Cation efflux family DUF1673 PF07895.6 KFM05881.1 - 0.035 13.6 0.6 0.035 13.6 0.4 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1673) DUF2721 PF11026.3 KFM05881.1 - 2.2 7.8 8.2 16 5.1 2.8 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) tRNA-synt_1c PF00749.16 KFM05882.1 - 4.6e-119 396.7 0.5 1.2e-118 395.3 0.3 1.8 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain WHEP-TRS PF00458.15 KFM05882.1 - 5.7e-87 285.2 44.9 6.7e-24 83.3 2.0 5.3 5 0 0 5 5 4 4 WHEP-TRS domain tRNA-synt_1c_C PF03950.13 KFM05882.1 - 9e-37 126.4 0.0 3.2e-36 124.6 0.0 2.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain ProRS-C_1 PF09180.6 KFM05882.1 - 2.3e-21 75.4 0.4 6.8e-21 73.9 0.3 1.9 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 KFM05882.1 - 1.9e-20 73.1 0.1 4.4e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KFM05882.1 - 9.7e-18 63.9 0.4 1.2e-16 60.4 0.0 3.0 3 0 0 3 3 3 1 Anticodon binding domain GST_C_3 PF14497.1 KFM05882.1 - 2.5e-11 43.9 2.5 1.5e-10 41.4 0.2 3.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KFM05882.1 - 0.00024 20.9 0.4 0.0023 17.8 0.0 3.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.14 KFM05882.1 - 0.011 14.8 0.6 0.026 13.6 0.4 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain GST_C_2 PF13410.1 KFM05882.1 - 0.025 14.4 0.0 0.088 12.7 0.0 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Adaptin_binding PF10199.4 KFM05882.1 - 2.1 8.6 16.5 0.14 12.4 5.8 3.0 3 0 0 3 3 3 0 Alpha and gamma adaptin binding protein p34 RuvC PF02075.12 KFM05882.1 - 4 7.2 4.8 46 3.8 0.1 3.5 3 0 0 3 3 3 0 Crossover junction endodeoxyribonuclease RuvC Inositol_P PF00459.20 KFM05883.1 - 1.5e-56 191.7 0.4 2e-56 191.3 0.3 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family tRNA-synt_1 PF00133.17 KFM05884.1 - 3.7e-168 560.2 0.2 5.2e-168 559.7 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KFM05884.1 - 3.1e-28 98.4 0.0 7.4e-28 97.2 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KFM05884.1 - 6.4e-28 97.5 0.4 3.3e-17 62.2 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 KFM05884.1 - 5.5e-05 22.5 0.0 9.4e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 KFM05884.1 - 0.00017 20.8 0.0 0.059 12.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain zf-FPG_IleRS PF06827.9 KFM05884.1 - 0.0025 17.3 5.1 0.0025 17.3 3.5 2.9 3 0 0 3 3 3 1 Zinc finger found in FPG and IleRS RAB3GAP2_C PF14656.1 KFM05885.1 - 2.1e-235 782.4 20.2 3.3e-235 781.7 14.0 1.3 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit C-terminus RAB3GAP2_N PF14655.1 KFM05885.1 - 1.5e-157 524.9 0.0 2.1e-157 524.4 0.0 1.2 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus SRP54_N PF02881.14 KFM05885.1 - 0.022 14.8 0.3 0.97 9.5 0.0 3.6 4 0 0 4 4 4 0 SRP54-type protein, helical bundle domain Pkinase PF00069.20 KFM05886.1 - 2.1e-77 259.8 0.0 3.1e-77 259.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM05886.1 - 4.9e-44 150.3 0.0 7.3e-44 149.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 KFM05886.1 - 8.5e-19 66.7 0.0 1.4e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.1 KFM05886.1 - 3e-07 29.7 0.0 6e-07 28.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 KFM05886.1 - 0.00016 21.1 0.3 0.00031 20.1 0.2 1.4 1 0 0 1 1 1 1 RIO1 family UBA PF00627.26 KFM05886.1 - 0.00023 20.8 0.0 0.00053 19.7 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Kdo PF06293.9 KFM05886.1 - 0.015 14.4 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UBA_2 PF08587.6 KFM05886.1 - 0.097 12.8 1.1 0.2 11.8 0.1 2.0 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) APH PF01636.18 KFM05886.1 - 0.15 11.7 0.1 0.53 9.9 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family MOSC PF03473.12 KFM05887.1 - 2e-29 101.7 0.0 3.5e-29 100.9 0.0 1.4 2 0 0 2 2 2 1 MOSC domain MOSC_N PF03476.11 KFM05887.1 - 3.2e-22 78.4 0.0 6.1e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain DSPc PF00782.15 KFM05888.1 - 3.1e-42 143.3 0.7 8.2e-42 141.9 0.1 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.15 KFM05888.1 - 1.1e-12 48.2 0.0 1.6e-11 44.5 0.0 2.4 2 0 0 2 2 2 1 Rhodanese-like domain PTPlike_phytase PF14566.1 KFM05888.1 - 5.3e-06 26.5 0.0 1.1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 KFM05888.1 - 2.9e-05 23.5 0.1 0.00062 19.1 0.0 2.2 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 KFM05888.1 - 0.0021 16.9 0.1 0.015 14.1 0.0 1.9 2 0 0 2 2 2 1 Initiator tRNA phosphoribosyl transferase Ank PF00023.25 KFM05890.1 - 2.7e-44 146.8 11.3 2.3e-07 30.2 0.1 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank_2 PF12796.2 KFM05890.1 - 6.5e-40 135.3 6.7 2.6e-21 75.7 0.4 2.6 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KFM05890.1 - 2.5e-30 101.4 7.7 8.6e-05 22.4 0.0 6.3 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 KFM05890.1 - 5.8e-30 103.1 2.8 1.2e-08 35.1 0.0 4.6 4 1 0 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM05890.1 - 1.7e-25 88.4 9.8 1.5e-06 28.2 0.2 5.7 1 1 5 6 6 6 6 Ankyrin repeats (many copies) SOCS_box PF07525.11 KFM05890.1 - 3.8e-08 33.0 4.4 7e-08 32.1 3.0 1.5 1 0 0 1 1 1 1 SOCS box Ank_2 PF12796.2 KFM05891.1 - 5e-46 154.9 7.0 2.8e-18 66.0 0.2 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFM05891.1 - 2.3e-41 137.5 6.0 6.3e-06 25.7 0.0 6.5 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 KFM05891.1 - 2.4e-31 107.5 6.4 1e-08 35.4 0.1 4.7 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM05891.1 - 1.7e-25 88.4 9.9 0.0001 22.4 0.1 6.3 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM05891.1 - 5.6e-25 84.9 4.4 0.00053 19.9 0.0 6.9 7 0 0 7 7 7 5 Ankyrin repeat SOCS_box PF07525.11 KFM05891.1 - 1.2e-12 47.5 5.0 2.2e-12 46.5 3.5 1.5 1 0 0 1 1 1 1 SOCS box TIR_2 PF13676.1 KFM05891.1 - 0.082 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 TIR domain Nucleotid_trans PF03407.11 KFM05891.1 - 0.091 12.5 0.0 0.31 10.7 0.0 1.8 2 0 0 2 2 2 0 Nucleotide-diphospho-sugar transferase PIGA PF08288.7 KFM05892.1 - 5.7e-43 145.1 2.1 5.7e-43 145.1 1.5 2.0 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 KFM05892.1 - 5.1e-26 91.1 0.0 8.6e-26 90.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KFM05892.1 - 1.1e-16 61.0 0.7 2.2e-16 60.0 0.5 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 KFM05892.1 - 2e-12 47.4 0.0 3.7e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KFM05892.1 - 6.1e-12 45.9 0.1 1.1e-11 45.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 KFM05892.1 - 0.0014 18.8 0.1 0.0069 16.6 0.0 2.3 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 KFM05892.1 - 0.0029 17.4 0.2 0.0047 16.7 0.2 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Dimeth_Pyl PF09505.5 KFM05892.1 - 0.048 11.9 0.0 0.094 10.9 0.0 1.4 1 0 0 1 1 1 0 Dimethylamine methyltransferase (Dimeth_PyL) Glyco_transf_5 PF08323.6 KFM05892.1 - 0.096 12.1 1.6 0.36 10.2 0.3 2.1 1 1 1 2 2 2 0 Starch synthase catalytic domain PDGF PF00341.12 KFM05893.1 - 2.3e-22 78.8 10.0 2.3e-22 78.8 6.9 2.5 2 1 0 2 2 2 1 PDGF/VEGF domain Baculo_p48 PF04878.8 KFM05893.1 - 0.085 11.7 0.5 0.13 11.1 0.4 1.2 1 0 0 1 1 1 0 Baculovirus P48 protein CXCXC PF03128.9 KFM05893.1 - 3 8.2 32.6 0.22 11.7 0.5 6.2 5 0 0 5 5 5 0 CXCXC repeat Pkinase_Tyr PF07714.12 KFM05894.1 - 9.9e-93 309.9 0.0 1.4e-92 309.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM05894.1 - 3.3e-45 154.2 0.0 5.5e-45 153.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 KFM05894.1 - 2.4e-22 78.5 0.2 5.6e-22 77.3 0.2 1.7 1 0 0 1 1 1 1 SH2 domain PH PF00169.24 KFM05894.1 - 1.6e-17 63.5 0.6 6e-17 61.7 0.4 2.0 1 0 0 1 1 1 1 PH domain BTK PF00779.14 KFM05894.1 - 1.8e-11 43.4 3.7 3.9e-11 42.3 2.6 1.6 1 0 0 1 1 1 1 BTK motif SH3_1 PF00018.23 KFM05894.1 - 5.9e-08 31.9 0.3 1.9e-07 30.3 0.1 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KFM05894.1 - 6.8e-07 28.7 0.7 1.7e-06 27.5 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KFM05894.1 - 5.7e-05 22.5 0.0 0.00018 20.8 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_3 PF08239.6 KFM05894.1 - 0.0012 18.9 0.2 0.0046 17.1 0.1 2.0 1 0 0 1 1 1 1 Bacterial SH3 domain PH_8 PF15409.1 KFM05894.1 - 0.0018 18.2 3.1 0.0091 16.0 1.1 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain Kinase-like PF14531.1 KFM05894.1 - 0.022 13.7 0.1 0.065 12.1 0.0 1.7 2 0 0 2 2 2 0 Kinase-like PH_3 PF14593.1 KFM05894.1 - 0.024 14.5 1.8 0.051 13.4 0.3 2.2 2 0 0 2 2 2 0 PH domain PH_11 PF15413.1 KFM05894.1 - 0.027 14.6 0.5 0.11 12.7 0.3 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain Peptidase_M2 PF01401.13 KFM05895.1 - 1.2e-198 661.1 8.6 1.6e-198 660.6 6.0 1.1 1 0 0 1 1 1 1 Angiotensin-converting enzyme DUF1191 PF06697.7 KFM05895.1 - 0.0076 15.0 0.0 0.014 14.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) TMEM154 PF15102.1 KFM05895.1 - 0.021 14.5 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.1 KFM05895.1 - 0.063 13.6 0.1 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3827 PF12877.2 KFM05895.1 - 0.1 10.6 0.2 0.15 10.0 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF1191 PF06697.7 KFM05896.1 - 2.8e-05 23.0 0.0 3.6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) DUF4381 PF14316.1 KFM05896.1 - 0.013 15.6 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF3816 PF12822.2 KFM05896.1 - 0.016 15.1 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) CcmH PF03918.9 KFM05896.1 - 0.022 13.7 0.0 0.042 12.8 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C biogenesis protein EphA2_TM PF14575.1 KFM05896.1 - 0.04 14.3 0.0 0.088 13.2 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain NfeD PF01957.13 KFM05896.1 - 0.053 13.6 0.0 0.096 12.8 0.0 1.4 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF2140 PF09911.4 KFM05896.1 - 0.056 12.6 0.2 0.31 10.1 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) zf-CCCH PF00642.19 KFM05897.1 - 2e-12 46.4 12.6 6.4e-07 28.9 2.6 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 KFM05897.1 - 3.2e-06 26.8 0.4 9.9e-06 25.3 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFM05897.1 - 0.00021 20.8 0.0 0.00048 19.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFM05897.1 - 0.00074 19.2 0.0 0.0017 18.0 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_6 PF14259.1 KFM05897.1 - 0.02 14.8 0.1 0.14 12.1 0.0 2.4 2 1 1 3 3 3 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3430 PF11912.3 KFM05897.1 - 0.093 12.5 0.6 0.14 11.9 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3430) Clat_adaptor_s PF01217.15 KFM05898.1 - 1.8e-60 202.7 2.2 2.1e-60 202.5 1.5 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain 7tm_1 PF00001.16 KFM05899.1 - 5.8e-55 186.2 13.2 8.2e-55 185.7 9.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM05899.1 - 1.3e-10 40.8 12.0 2.9e-10 39.7 8.3 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 KFM05899.1 - 7.6e-10 38.3 9.8 1.4e-09 37.5 6.8 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv DUF962 PF06127.6 KFM05899.1 - 1.8 8.5 5.7 7.4 6.5 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF962) BSD PF03909.12 KFM05900.1 - 1.7e-16 59.7 0.1 1.7e-16 59.7 0.1 2.4 3 1 0 3 3 3 1 BSD domain CCDC84 PF14968.1 KFM05900.1 - 0.024 14.1 6.4 0.31 10.5 0.0 2.4 2 0 0 2 2 2 0 Coiled coil protein 84 Ima1_N PF09779.4 KFM05900.1 - 0.8 10.1 4.7 0.33 11.4 1.2 1.9 2 0 0 2 2 2 0 Ima1 N-terminal domain Taxilin PF09728.4 KFM05901.1 - 4.1e-116 387.3 69.2 4.6e-116 387.2 48.0 1.0 1 0 0 1 1 1 1 Myosin-like coiled-coil protein HTH_26 PF13443.1 KFM05901.1 - 0.17 12.1 3.4 0.8 9.9 0.0 3.5 4 1 0 4 4 4 0 Cro/C1-type HTH DNA-binding domain UPF0270 PF06794.7 KFM05901.1 - 0.88 9.3 11.4 1.8 8.3 0.3 3.8 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0270) WD40 PF00400.27 KFM05902.1 - 8.5e-38 126.9 12.8 6.3e-09 35.3 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KFM05902.1 - 5.4e-30 103.1 0.5 1.5e-29 101.6 0.4 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 KFM05902.1 - 2.3e-05 24.1 0.2 0.016 14.9 0.0 3.0 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Capsid_NCLDV PF04451.7 KFM05902.1 - 0.03 13.3 0.0 0.052 12.5 0.0 1.4 1 0 0 1 1 1 0 Large eukaryotic DNA virus major capsid protein EF-hand_4 PF12763.2 KFM05903.1 - 1.6e-13 50.2 0.0 3.7e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 KFM05903.1 - 0.0091 16.1 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 KFM05903.1 - 0.0098 15.4 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KFM05903.1 - 0.019 14.2 0.0 0.036 13.3 0.0 1.5 1 0 0 1 1 1 0 EF hand MCC-bdg_PDZ PF10506.4 KFM05903.1 - 0.089 12.6 2.7 0.18 11.6 0.9 2.1 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF4200 PF13863.1 KFM05903.1 - 4.3 7.3 12.0 2.2 8.2 4.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) BEN PF10523.4 KFM05904.1 - 2.3e-29 101.2 0.5 8.4e-14 51.3 0.0 2.6 2 0 0 2 2 2 2 BEN domain DUF1647 PF07801.6 KFM05904.1 - 0.047 13.2 0.0 2.9 7.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) Pkinase PF00069.20 KFM05905.1 - 2e-73 246.7 0.0 3.3e-73 246.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM05905.1 - 1.7e-34 119.0 0.0 3e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM05905.1 - 0.039 12.9 0.1 1.9 7.3 0.0 2.3 1 1 1 2 2 2 0 Kinase-like APH PF01636.18 KFM05905.1 - 0.36 10.5 1.6 2.3 7.8 0.1 2.6 2 1 0 3 3 3 0 Phosphotransferase enzyme family F5_F8_type_C PF00754.20 KFM05906.1 - 1.5e-31 108.9 0.7 2.1e-31 108.4 0.5 1.3 1 0 0 1 1 1 1 F5/8 type C domain Glyco_hydro_15 PF00723.16 KFM05907.1 - 1.5e-181 603.8 0.0 1.8e-181 603.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 7tm_2 PF00002.19 KFM05908.1 - 1.7e-57 194.2 23.5 1.7e-57 194.2 16.3 1.7 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) GPS PF01825.16 KFM05908.1 - 3.2e-15 55.9 3.1 9e-15 54.5 2.2 1.8 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain E1_dh PF00676.15 KFM05910.1 - 3.4e-123 410.1 0.0 4e-123 409.9 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 KFM05910.1 - 0.01 14.7 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase DUF4071 PF13281.1 KFM05911.1 - 7.8e-158 525.1 0.3 1.5e-157 524.2 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4071) Pkinase PF00069.20 KFM05911.1 - 2.6e-64 216.8 0.0 4.8e-64 216.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM05911.1 - 4.7e-42 143.8 0.0 8.8e-42 142.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM05911.1 - 0.00028 19.9 0.0 0.00067 18.7 0.0 1.6 1 0 0 1 1 1 1 Kinase-like RICH PF05062.7 KFM05911.1 - 0.28 11.3 4.9 1.1 9.4 0.6 2.8 2 0 0 2 2 2 0 RICH domain SH3_9 PF14604.1 KFM05912.1 - 2.4e-54 180.6 4.5 8e-18 63.7 0.1 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.23 KFM05912.1 - 1.8e-43 145.6 7.7 3e-15 55.3 0.3 3.4 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.12 KFM05912.1 - 4.8e-43 144.4 4.4 1.7e-13 49.8 0.1 3.4 3 0 0 3 3 3 3 Variant SH3 domain XFP PF03894.10 KFM05912.1 - 0.0013 18.3 0.0 3.1 7.3 0.0 3.0 3 0 0 3 3 3 2 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase Tmemb_cc2 PF10267.4 KFM05912.1 - 0.0015 17.2 0.4 0.0026 16.4 0.3 1.4 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein THRAP3_BCLAF1 PF15440.1 KFM05914.1 - 5.8e-80 269.7 10.4 6.5e-80 269.6 7.2 1.0 1 0 0 1 1 1 1 THRAP3/BCLAF1 family SF-assemblin PF06705.6 KFM05914.1 - 0.018 14.2 1.4 0.029 13.5 0.7 1.5 1 1 0 1 1 1 0 SF-assemblin/beta giardin MtrG PF04210.8 KFM05914.1 - 0.75 9.5 0.1 0.75 9.5 0.0 2.3 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G MAP7 PF05672.6 KFM05915.1 - 1e-52 177.9 79.8 1e-52 177.9 55.3 3.1 3 0 0 3 3 3 1 MAP7 (E-MAP-115) family PSRT PF07636.6 KFM05915.1 - 3.5 7.1 10.1 0.28 10.6 2.0 2.8 2 1 0 2 2 2 0 PSRT eIF-1a PF01176.14 KFM05916.1 - 1.8e-27 94.5 0.2 2.3e-27 94.1 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Pkinase PF00069.20 KFM05917.1 - 5.7e-144 477.9 0.0 2.4e-71 239.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFM05917.1 - 2e-78 263.0 0.0 8.1e-42 143.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KFM05917.1 - 3.6e-15 55.6 0.0 1.6e-08 33.8 0.0 2.9 3 1 0 3 3 3 2 Kinase-like Kdo PF06293.9 KFM05917.1 - 1.1e-10 40.9 0.0 1.7e-05 23.9 0.0 2.9 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.19 KFM05917.1 - 3.3e-08 33.9 0.3 7.2e-08 32.8 0.2 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain YrbL-PhoP_reg PF10707.4 KFM05917.1 - 3.1e-06 26.6 0.0 0.0047 16.2 0.0 2.5 2 0 0 2 2 2 2 PhoP regulatory network protein YrbL APH PF01636.18 KFM05917.1 - 6.7e-06 26.0 0.0 0.099 12.3 0.0 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family tRNA-synt_1f PF01921.13 KFM05917.1 - 0.01 14.5 0.0 0.02 13.5 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) RIO1 PF01163.17 KFM05917.1 - 0.023 14.0 0.3 1.4 8.2 0.0 2.6 3 0 0 3 3 3 0 RIO1 family Yae1_N PF09811.4 KFM05919.1 - 1e-11 44.1 30.7 1 8.9 21.2 3.1 1 1 0 1 1 1 1 Essential protein Yae1, N terminal DUF1170 PF06663.8 KFM05920.1 - 1e-79 266.8 5.3 1e-79 266.8 3.7 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1170) CRIC_ras_sig PF10534.4 KFM05920.1 - 3.5e-44 148.7 1.7 7.6e-44 147.6 0.1 2.4 3 0 0 3 3 3 1 Connector enhancer of kinase suppressor of ras SAM_1 PF00536.25 KFM05920.1 - 1e-14 54.4 2.9 1.9e-14 53.5 0.2 2.8 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) PH PF00169.24 KFM05920.1 - 1.2e-13 51.1 6.3 1.9e-13 50.5 2.4 2.6 2 0 0 2 2 2 1 PH domain SAM_2 PF07647.12 KFM05920.1 - 5.3e-10 39.0 0.6 3.7e-09 36.2 0.2 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PDZ PF00595.19 KFM05920.1 - 5.3e-09 36.1 0.1 1.6e-08 34.6 0.0 1.8 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) PH_9 PF15410.1 KFM05920.1 - 0.00038 20.5 2.5 0.094 12.8 2.0 3.5 3 1 0 3 3 3 1 Pleckstrin homology domain PDZ_2 PF13180.1 KFM05920.1 - 0.0036 17.1 0.2 0.035 13.9 0.0 2.5 2 0 0 2 2 2 1 PDZ domain ATG11 PF10377.4 KFM05920.1 - 0.031 14.1 0.5 0.087 12.7 0.3 1.7 1 0 0 1 1 1 0 Autophagy-related protein 11 PH_11 PF15413.1 KFM05920.1 - 0.63 10.3 14.4 0.063 13.5 4.9 3.1 2 2 0 2 2 2 0 Pleckstrin homology domain Kelch_1 PF01344.20 KFM05921.1 - 3.2e-42 141.8 0.3 5.9e-10 38.5 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 KFM05921.1 - 3.3e-34 115.6 0.2 5.9e-08 32.5 0.0 6.3 1 1 5 6 6 6 5 Kelch motif Kelch_4 PF13418.1 KFM05921.1 - 2.3e-26 91.2 0.1 8.1e-08 31.9 0.0 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain BTB PF00651.26 KFM05921.1 - 8.7e-26 90.0 0.5 1.9e-25 88.9 0.3 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_3 PF13415.1 KFM05921.1 - 3.1e-24 84.5 0.0 0.0003 20.8 0.0 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.10 KFM05921.1 - 2.4e-15 55.5 2.4 3.4e-05 23.4 0.1 5.3 5 1 0 5 5 5 4 Kelch motif Kelch_5 PF13854.1 KFM05921.1 - 1.4e-11 44.0 0.7 0.0091 15.9 0.0 5.3 5 0 0 5 5 5 3 Kelch motif BACK PF07707.10 KFM05921.1 - 1.1e-10 41.2 0.1 2.4e-10 40.1 0.1 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Chisel PF15355.1 KFM05923.1 - 2e-41 139.8 3.1 2.2e-41 139.7 2.2 1.0 1 0 0 1 1 1 1 Stretch-responsive small skeletal muscle X protein, Chisel Spermine_synth PF01564.12 KFM05924.1 - 9.5e-61 204.8 0.1 1.2e-60 204.5 0.1 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Peptidase_M13_N PF05649.8 KFM05925.1 - 1.8e-116 389.4 2.8 2.3e-116 389.0 1.9 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 KFM05925.1 - 2.2e-56 190.2 0.2 4.3e-56 189.3 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M13 Patched PF02460.13 KFM05926.1 - 3.9e-97 326.0 22.3 7e-97 325.2 15.5 1.3 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 KFM05926.1 - 1.8e-24 85.9 2.4 1.8e-24 85.9 1.7 2.4 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation AhpC-TSA PF00578.16 KFM05927.1 - 3.4e-36 123.6 0.0 4.3e-36 123.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KFM05927.1 - 2.1e-13 50.0 0.0 2.6e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 KFM05927.1 - 1.5e-10 40.5 0.7 2.6e-10 39.7 0.1 1.7 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin 4HBT PF03061.17 KFM05928.1 - 1.3e-10 41.2 0.0 0.00011 22.2 0.0 2.3 2 0 0 2 2 2 2 Thioesterase superfamily Acetyltransf_1 PF00583.19 KFM05929.1 - 4.4e-16 58.6 0.0 6.2e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFM05929.1 - 6.6e-08 32.6 0.2 1.3e-07 31.6 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFM05929.1 - 1.4e-05 25.1 0.0 1.7e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFM05929.1 - 0.00054 19.6 0.0 0.00096 18.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 KFM05929.1 - 0.0086 16.0 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KFM05929.1 - 0.035 14.2 0.0 0.041 14.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ApoO PF09769.4 KFM05930.1 - 3.5e-27 95.0 0.0 4e-27 94.8 0.0 1.0 1 0 0 1 1 1 1 Apolipoprotein O Kelch_1 PF01344.20 KFM05931.1 - 8.4e-47 156.4 8.9 1.4e-12 46.9 0.0 5.7 5 1 0 5 5 5 5 Kelch motif Kelch_6 PF13964.1 KFM05931.1 - 1.5e-36 123.0 2.7 2.5e-10 40.0 0.0 5.7 3 2 2 5 5 5 5 Kelch motif BTB PF00651.26 KFM05931.1 - 4.4e-24 84.6 1.8 4.4e-24 84.6 1.2 2.2 2 0 0 2 2 2 1 BTB/POZ domain Kelch_4 PF13418.1 KFM05931.1 - 5e-22 77.4 3.6 0.00064 19.4 0.0 6.2 5 1 0 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.1 KFM05931.1 - 1.3e-19 69.7 0.4 6.4e-06 26.1 0.0 5.7 5 1 0 5 5 5 4 Galactose oxidase, central domain BACK PF07707.10 KFM05931.1 - 9.5e-17 60.7 0.6 2e-16 59.6 0.1 1.8 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_2 PF07646.10 KFM05931.1 - 2e-14 52.7 11.4 0.00097 18.8 0.0 6.1 6 1 0 6 6 6 4 Kelch motif Kelch_5 PF13854.1 KFM05931.1 - 2e-08 33.9 6.6 1.3 9.0 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Rax2 PF12768.2 KFM05931.1 - 0.0003 20.1 0.0 0.011 15.0 0.0 2.7 3 0 0 3 3 3 1 Cortical protein marker for cell polarity GTP_EFTU PF00009.22 KFM05932.1 - 7.9e-40 136.2 0.1 1.2e-39 135.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 KFM05932.1 - 5.1e-32 109.7 0.0 1.2e-31 108.5 0.0 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 KFM05932.1 - 1e-12 47.9 0.3 2.6e-12 46.6 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KFM05932.1 - 0.004 17.0 0.0 0.011 15.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KFM05932.1 - 0.079 12.7 0.3 0.43 10.3 0.2 2.2 1 1 0 1 1 1 0 Dynamin family Zfx_Zfy_act PF04704.8 KFM05933.1 - 1e-162 540.6 23.2 1e-162 540.6 16.0 1.4 2 0 0 2 2 2 1 Zfx / Zfy transcription activation region zf-H2C2_2 PF13465.1 KFM05933.1 - 8.7e-47 155.1 118.8 2.8e-08 33.6 0.8 13.5 13 0 0 13 13 13 12 Zinc-finger double domain zf-C2H2 PF00096.21 KFM05933.1 - 5.9e-40 133.2 117.0 1.4e-05 25.1 1.3 13.4 13 0 0 13 13 13 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM05933.1 - 5.7e-30 101.4 99.2 0.00053 20.1 1.5 13.4 13 0 0 13 13 13 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM05933.1 - 1.3e-17 63.3 71.7 0.0011 18.9 0.0 12.3 12 0 0 12 12 12 7 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 KFM05933.1 - 7.1e-16 57.4 94.9 0.00044 20.3 1.0 12.3 12 0 0 12 12 12 8 C2H2-type zinc-finger domain ROS_MUCR PF05443.6 KFM05933.1 - 0.013 15.3 0.1 0.013 15.3 0.1 3.4 4 0 0 4 4 4 0 ROS/MUCR transcriptional regulator protein Adhes-Ig_like PF09085.5 KFM05933.1 - 0.14 12.0 1.2 0.37 10.6 0.8 1.7 1 0 0 1 1 1 0 Adhesion molecule, immunoglobulin-like zf-met PF12874.2 KFM05933.1 - 0.26 11.5 0.0 0.26 11.5 0.0 11.6 12 1 0 12 12 12 0 Zinc-finger of C2H2 type Solute_trans_a PF03619.11 KFM05934.1 - 5.7e-23 81.5 17.6 7e-23 81.3 12.2 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF2359 PF10151.4 KFM05934.1 - 0.023 13.2 1.3 0.039 12.4 0.9 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2359) BCDHK_Adom3 PF10436.4 KFM05935.1 - 8.6e-54 181.4 0.0 1.3e-53 180.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KFM05935.1 - 3.5e-19 68.5 0.0 5.2e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KFM05935.1 - 0.0073 15.9 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CTP_transf_2 PF01467.21 KFM05936.1 - 3.7e-23 82.2 0.0 6.3e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase Lipoprotein_6 PF01441.14 KFM05936.1 - 0.039 13.8 2.0 0.066 13.0 1.4 1.3 1 0 0 1 1 1 0 Lipoprotein UPF0158 PF03682.8 KFM05936.1 - 0.23 11.0 6.4 2.8 7.5 4.2 2.2 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0158) DNA_pol_B PF00136.16 KFM05937.1 - 2.5e-123 412.2 0.2 3.9e-123 411.6 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 KFM05937.1 - 4e-56 189.3 7.8 7.3e-56 188.5 5.4 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 KFM05937.1 - 7.1e-54 182.8 0.0 1.7e-53 181.5 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 KFM05937.1 - 1.2e-15 57.0 13.2 1.2e-15 57.0 9.2 2.7 3 0 0 3 3 3 1 DNA polymerase alpha subunit p180 N terminal DUF1744 PF08490.7 KFM05937.1 - 0.0087 14.6 0.4 0.041 12.4 0.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1744) Glyco_transf_29 PF00777.13 KFM05939.1 - 9.3e-77 257.7 0.0 1.1e-76 257.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Herpes_BBRF1 PF04793.7 KFM05939.1 - 0.12 11.0 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 BRRF1-like protein Lig_chan PF00060.21 KFM05940.1 - 3.2e-60 202.1 0.0 4.7e-60 201.5 0.0 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel ANF_receptor PF01094.23 KFM05940.1 - 4.7e-37 127.5 0.0 1e-36 126.4 0.0 1.5 2 0 0 2 2 2 1 Receptor family ligand binding region Lig_chan-Glu_bd PF10613.4 KFM05940.1 - 4.5e-27 93.8 0.1 1.2e-26 92.4 0.1 1.8 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.15 KFM05940.1 - 1.2e-25 90.1 0.0 2.3e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.1 KFM05940.1 - 0.0054 16.1 0.0 0.066 12.5 0.0 2.1 2 0 0 2 2 2 1 Periplasmic binding protein Myb_DNA-bind_5 PF13873.1 KFM05941.1 - 1.7e-22 79.1 6.7 1.7e-22 79.1 4.7 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain AsmA PF05170.9 KFM05941.1 - 0.007 15.0 1.0 0.0097 14.5 0.7 1.2 1 0 0 1 1 1 1 AsmA family Myb_DNA-bind_4 PF13837.1 KFM05941.1 - 0.0078 16.3 2.3 0.02 15.0 1.6 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Flagellin_C PF00700.16 KFM05941.1 - 0.11 12.6 3.0 0.19 11.8 0.5 2.5 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region Myb_DNA-binding PF00249.26 KFM05941.1 - 0.11 12.5 0.0 0.11 12.5 0.0 2.2 2 1 0 2 2 2 0 Myb-like DNA-binding domain DUF2125 PF09898.4 KFM05941.1 - 0.13 11.4 1.9 0.95 8.7 0.4 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2125) HALZ PF02183.13 KFM05941.1 - 0.16 11.6 40.2 0.26 11.0 1.3 6.0 3 2 4 7 7 7 0 Homeobox associated leucine zipper DUF3540 PF12059.3 KFM05941.1 - 0.56 9.8 5.3 0.77 9.3 0.9 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3540) FtsL PF04999.8 KFM05941.1 - 2 8.1 32.5 0.83 9.4 3.2 4.3 2 2 2 4 4 4 0 Cell division protein FtsL BTB PF00651.26 KFM05942.1 - 2.8e-27 94.8 1.1 2.8e-27 94.8 0.7 2.0 2 1 0 2 2 2 1 BTB/POZ domain Kelch_6 PF13964.1 KFM05942.1 - 1.1e-26 91.8 3.8 1.1e-05 25.3 0.0 6.7 2 2 4 6 6 6 5 Kelch motif Kelch_1 PF01344.20 KFM05942.1 - 2.3e-26 91.0 6.1 4.9e-07 29.1 0.0 6.2 6 1 0 6 6 6 5 Kelch motif BACK PF07707.10 KFM05942.1 - 3.3e-26 91.1 2.2 3.3e-26 91.1 1.5 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_4 PF13418.1 KFM05942.1 - 9.9e-12 44.4 0.0 0.054 13.2 0.0 5.0 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.1 KFM05942.1 - 1.1e-09 38.1 0.0 1.1 9.5 0.0 5.0 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_2 PF07646.10 KFM05942.1 - 3.7e-06 26.4 2.8 0.087 12.6 0.0 5.5 5 1 0 5 5 5 1 Kelch motif Kelch_5 PF13854.1 KFM05942.1 - 0.00073 19.4 0.1 2.8 8.0 0.0 3.6 3 0 0 3 3 3 2 Kelch motif ACPS PF01648.15 KFM05943.1 - 2.5e-16 59.5 0.0 8.2e-15 54.6 0.0 2.2 2 0 0 2 2 2 2 4'-phosphopantetheinyl transferase superfamily HNOBA PF07701.9 KFM05944.1 - 8.7e-63 211.4 2.2 4.2e-62 209.2 1.6 1.9 1 1 0 1 1 1 1 Heme NO binding associated Guanylate_cyc PF00211.15 KFM05944.1 - 1.2e-60 204.0 0.0 1.9e-60 203.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOB PF07700.10 KFM05944.1 - 1.6e-15 57.0 0.1 2.7e-15 56.2 0.1 1.3 1 0 0 1 1 1 1 Heme NO binding VOMI PF03762.12 KFM05945.1 - 1.4e-20 74.0 4.9 3.1e-18 66.3 0.5 2.1 2 0 0 2 2 2 2 Vitelline membrane outer layer protein I (VOMI) VOMI PF03762.12 KFM05946.1 - 7e-34 117.2 0.8 8.3e-34 117.0 0.5 1.1 1 0 0 1 1 1 1 Vitelline membrane outer layer protein I (VOMI) 2OG-FeII_Oxy_2 PF13532.1 KFM05948.1 - 1.2e-22 80.7 0.0 2.4e-22 79.6 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_11 PF08241.7 KFM05948.1 - 1.8e-14 53.9 0.0 5.3e-14 52.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain 2OG-FeII_Oxy PF03171.15 KFM05948.1 - 1.1e-09 38.5 0.0 2.1e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RRM_1 PF00076.17 KFM05948.1 - 1e-08 34.7 0.1 3.3e-08 33.0 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_23 PF13489.1 KFM05948.1 - 5.3e-08 32.7 0.0 1.6e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFM05948.1 - 1.1e-06 28.8 0.0 6.8e-06 26.3 0.1 2.3 2 0 0 2 2 2 1 Methyltransferase domain RRM_6 PF14259.1 KFM05948.1 - 2e-06 27.6 0.0 6.7e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Methyltransf_31 PF13847.1 KFM05948.1 - 2.9e-06 26.9 0.0 6.2e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KFM05948.1 - 4.4e-05 23.2 0.0 9.3e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Hypothetical methyltransferase RRM_5 PF13893.1 KFM05948.1 - 5.9e-05 22.8 0.1 0.00019 21.2 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_12 PF08242.7 KFM05948.1 - 6.3e-05 23.3 0.0 0.0002 21.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain DUF1891 PF09004.5 KFM05948.1 - 0.00093 18.5 0.6 0.0019 17.5 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1891) Methyltransf_26 PF13659.1 KFM05948.1 - 0.0013 18.7 0.1 0.0028 17.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFM05948.1 - 0.0088 16.6 0.2 0.029 14.9 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KFM05948.1 - 0.015 14.0 0.0 0.028 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.13 KFM05948.1 - 0.036 13.1 0.0 0.092 11.8 0.0 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family MetW PF07021.7 KFM05948.1 - 0.082 12.2 0.1 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW ELMO_CED12 PF04727.8 KFM05949.1 - 1.1e-50 171.4 0.1 1.5e-50 171.0 0.0 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family COX6C PF02937.10 KFM05950.1 - 2.2e-23 81.9 1.1 2.3e-23 81.8 0.8 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIc NS3_envE PF02723.9 KFM05950.1 - 0.081 12.8 0.0 0.088 12.7 0.0 1.1 1 0 0 1 1 1 0 Non-structural protein NS3/Small envelope protein E Ras PF00071.17 KFM05951.1 - 3.2e-29 101.4 0.1 3.8e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM05951.1 - 0.0023 18.4 0.0 0.0049 17.3 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM05951.1 - 0.022 14.0 0.0 0.027 13.7 0.0 1.1 1 0 0 1 1 1 0 ADP-ribosylation factor family Thiolase_N PF00108.18 KFM05952.1 - 7.6e-103 343.0 2.8 1e-102 342.6 1.9 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KFM05952.1 - 2e-46 156.4 3.4 2.1e-46 156.3 0.7 2.2 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KFM05952.1 - 3.7e-05 23.3 3.1 3.7e-05 23.3 2.2 2.4 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.5 KFM05952.1 - 0.094 12.7 0.4 0.77 9.8 0.0 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Glyco_transf_90 PF05686.7 KFM05953.1 - 2.5e-86 289.8 0.3 3.1e-86 289.5 0.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 KFM05953.1 - 0.00077 19.6 0.0 0.0015 18.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Filamin PF00630.14 KFM05953.1 - 0.0047 17.4 0.0 0.0086 16.6 0.0 1.5 1 0 0 1 1 1 1 Filamin/ABP280 repeat RVT_1 PF00078.22 KFM05954.1 - 0.0039 16.5 0.0 0.0068 15.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Methyltransf_26 PF13659.1 KFM05955.1 - 1.5e-06 28.1 0.0 2.7e-06 27.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFM05955.1 - 2e-06 28.3 0.0 3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFM05955.1 - 6.7e-06 25.9 0.0 8.4e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFM05955.1 - 0.00028 20.3 0.0 0.00035 19.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 KFM05955.1 - 0.00032 20.3 0.0 0.00041 19.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.8 KFM05955.1 - 0.017 15.2 0.0 0.028 14.5 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase PrmA PF06325.8 KFM05955.1 - 0.018 14.2 0.0 0.021 13.9 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 KFM05955.1 - 0.088 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase N6_N4_Mtase PF01555.13 KFM05955.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 DNA methylase Cpn60_TCP1 PF00118.19 KFM05956.1 - 3.1e-146 487.8 1.7 3.8e-146 487.5 1.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pkinase PF00069.20 KFM05958.1 - 9.7e-43 146.1 0.0 1.2e-42 145.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM05958.1 - 9e-22 77.3 0.0 1.1e-21 77.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM05958.1 - 3e-06 26.4 0.0 2.5e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like GRDA PF04723.9 KFM05958.1 - 0.1 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Glycine reductase complex selenoprotein A DLH PF01738.13 KFM05959.1 - 1.6e-39 135.4 0.0 1.8e-39 135.2 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KFM05959.1 - 1.5e-13 50.7 0.0 1.9e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFM05959.1 - 7.9e-11 42.2 0.0 2.8e-07 30.6 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KFM05959.1 - 1.9e-08 34.0 0.0 2.7e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 KFM05959.1 - 4.1e-06 26.1 0.2 0.00012 21.3 0.0 2.2 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KFM05959.1 - 0.00049 19.7 0.2 0.02 14.4 0.1 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.8 KFM05959.1 - 0.04 13.3 0.1 0.11 11.9 0.1 1.7 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 KFM05959.1 - 0.061 12.8 0.0 0.19 11.2 0.0 1.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold SLIDE PF09111.5 KFM05959.1 - 0.072 12.8 0.0 0.2 11.4 0.0 1.7 2 0 0 2 2 2 0 SLIDE DLH PF01738.13 KFM05960.1 - 1.2e-40 139.1 0.0 1.3e-40 138.9 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KFM05960.1 - 5.1e-15 55.4 0.0 6.8e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFM05960.1 - 3.5e-10 40.1 0.0 7.4e-07 29.2 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KFM05960.1 - 2.7e-07 30.2 0.0 3.7e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 KFM05960.1 - 9.8e-07 28.2 0.1 0.00019 20.7 0.0 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KFM05960.1 - 6.8e-06 25.7 1.1 0.0013 18.2 0.1 2.5 2 1 1 3 3 3 2 alpha/beta hydrolase fold DUF915 PF06028.6 KFM05960.1 - 0.0023 17.0 0.0 0.0029 16.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_3 PF07859.8 KFM05960.1 - 0.014 14.9 0.0 0.096 12.2 0.0 2.0 1 1 1 2 2 2 0 alpha/beta hydrolase fold SLIDE PF09111.5 KFM05960.1 - 0.065 12.9 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 SLIDE DLH PF01738.13 KFM05961.1 - 4e-33 114.5 0.0 4.6e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KFM05961.1 - 1.5e-11 44.2 0.0 1.9e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFM05961.1 - 1.5e-09 38.0 0.0 1.3e-06 28.5 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KFM05961.1 - 4.3e-09 36.1 0.0 5.7e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 KFM05961.1 - 1.4e-07 31.3 0.2 0.0001 21.9 0.1 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFM05961.1 - 2e-07 30.4 0.1 0.0015 17.7 0.0 2.3 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 KFM05961.1 - 3.9e-05 23.3 0.0 0.038 13.5 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 KFM05961.1 - 0.0002 20.3 0.0 0.00029 19.8 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 KFM05961.1 - 0.00094 18.0 0.0 0.0014 17.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase DUF915 PF06028.6 KFM05961.1 - 0.0021 17.1 0.0 0.003 16.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) FSH1 PF03959.8 KFM05961.1 - 0.0022 17.4 0.1 0.0093 15.4 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) tRNA-synt_2b PF00587.20 KFM05961.1 - 0.1 12.1 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) RINGv PF12906.2 KFM05962.1 - 1.1e-14 54.1 9.0 2.8e-14 52.8 6.3 1.8 1 0 0 1 1 1 1 RING-variant domain Ank_2 PF12796.2 KFM05965.1 - 3.1e-19 69.0 0.3 5.9e-14 52.1 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFM05965.1 - 7.5e-16 57.8 1.2 7e-06 26.1 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFM05965.1 - 3e-14 53.0 0.3 1.8e-06 28.2 0.3 3.3 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KFM05965.1 - 9.8e-12 44.0 0.6 1.6e-05 24.4 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 KFM05965.1 - 3.3e-11 42.2 0.3 0.0024 17.9 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat DAP PF15228.1 KFM05966.1 - 4e-25 88.3 8.3 4.4e-25 88.2 5.8 1.0 1 0 0 1 1 1 1 Death-associated protein Arm PF00514.18 KFM05967.1 - 2.2e-46 154.1 9.6 4e-09 35.9 0.0 9.0 9 0 0 9 9 9 7 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFM05967.1 - 9.5e-11 41.8 0.8 8.4e-05 22.7 0.0 3.4 3 1 0 3 3 3 2 HEAT repeats HEAT PF02985.17 KFM05967.1 - 4e-05 23.3 3.2 0.91 9.7 0.0 5.3 6 0 0 6 6 6 1 HEAT repeat Adaptin_N PF01602.15 KFM05967.1 - 0.0067 14.7 0.0 0.38 9.0 0.0 2.1 2 0 0 2 2 2 2 Adaptin N terminal region HEAT_EZ PF13513.1 KFM05967.1 - 0.021 15.3 4.4 37 4.9 0.1 5.1 4 1 1 5 5 5 0 HEAT-like repeat Pkinase PF00069.20 KFM05970.1 - 1.2e-70 237.6 0.1 1.8e-70 237.0 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM05970.1 - 4.4e-38 130.8 0.0 6.9e-38 130.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFM05970.1 - 2.4e-06 26.7 0.5 4.5e-06 25.8 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KFM05970.1 - 6.3e-06 25.3 0.0 9.4e-06 24.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KFM05970.1 - 1.1e-05 24.8 1.1 1.9e-05 24.1 0.8 1.3 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 KFM05970.1 - 0.035 12.6 1.0 0.054 12.0 0.7 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC APH PF01636.18 KFM05970.1 - 0.16 11.7 0.4 0.51 10.0 0.3 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family SRF-TF PF00319.13 KFM05970.1 - 4.1 6.6 10.8 23 4.3 0.0 4.5 5 0 0 5 5 5 0 SRF-type transcription factor (DNA-binding and dimerisation domain) IncA PF04156.9 KFM05971.1 - 2.1e-05 24.2 49.4 0.0077 15.8 2.4 4.7 1 1 3 4 4 4 3 IncA protein Reo_sigmaC PF04582.7 KFM05971.1 - 2.2e-05 23.8 36.9 0.0011 18.1 9.4 4.4 1 1 3 4 4 4 2 Reovirus sigma C capsid protein AAA_13 PF13166.1 KFM05971.1 - 5.3e-05 21.9 46.0 0.0058 15.1 15.5 3.1 1 1 2 3 3 3 3 AAA domain Filament PF00038.16 KFM05971.1 - 8.3e-05 22.1 44.7 0.15 11.5 9.1 3.9 1 1 3 4 4 4 4 Intermediate filament protein Baculo_PEP_C PF04513.7 KFM05971.1 - 0.00012 21.8 34.3 0.065 13.0 1.4 5.0 1 1 3 4 4 4 3 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin_1 PF12718.2 KFM05971.1 - 0.00032 20.5 16.1 0.00032 20.5 11.2 5.1 2 2 2 5 5 5 2 Tropomyosin like GAS PF13851.1 KFM05971.1 - 0.0029 16.8 48.1 0.012 14.8 10.2 4.6 1 1 2 4 4 4 3 Growth-arrest specific micro-tubule binding WEMBL PF05701.6 KFM05971.1 - 0.0034 15.9 49.5 0.043 12.2 7.6 2.7 1 1 1 2 2 2 2 Weak chloroplast movement under blue light Fib_alpha PF08702.5 KFM05971.1 - 0.0054 16.8 45.2 0.06 13.4 1.0 5.5 1 1 5 6 6 6 3 Fibrinogen alpha/beta chain family Hemerythrin PF01814.18 KFM05971.1 - 0.0066 16.6 7.3 17 5.5 1.6 3.7 2 1 1 3 3 3 0 Hemerythrin HHE cation binding domain Tropomyosin PF00261.15 KFM05971.1 - 0.0078 15.3 47.3 0.015 14.4 3.9 5.3 1 1 2 4 4 4 2 Tropomyosin BLOC1_2 PF10046.4 KFM05971.1 - 0.01 15.9 0.8 0.01 15.9 0.5 7.2 2 2 3 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-F_leu_zip PF10473.4 KFM05971.1 - 0.037 13.8 55.2 0.081 12.7 0.5 5.3 1 1 4 5 5 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4172 PF13776.1 KFM05971.1 - 0.061 13.4 5.0 0.18 11.9 0.8 3.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4172) Syntaxin-6_N PF09177.6 KFM05971.1 - 0.068 13.5 39.4 0.18 12.2 3.4 6.1 2 1 3 5 5 5 0 Syntaxin 6, N-terminal EzrA PF06160.7 KFM05971.1 - 0.073 11.2 40.9 0.91 7.6 5.5 4.0 1 1 3 4 4 4 0 Septation ring formation regulator, EzrA DUF869 PF05911.6 KFM05971.1 - 0.076 11.2 50.3 0.45 8.6 3.6 2.8 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) Snapin_Pallidin PF14712.1 KFM05971.1 - 0.088 13.1 43.3 1.3 9.3 0.1 7.3 1 1 7 8 8 8 0 Snapin/Pallidin DUF4200 PF13863.1 KFM05971.1 - 0.13 12.1 43.7 0.74 9.7 2.1 6.0 3 1 2 6 6 5 0 Domain of unknown function (DUF4200) Cob_adeno_trans PF01923.13 KFM05971.1 - 0.18 11.5 20.6 1.6 8.4 0.4 5.2 1 1 3 5 5 5 0 Cobalamin adenosyltransferase DUF3584 PF12128.3 KFM05971.1 - 0.24 8.6 41.7 0.51 7.6 12.2 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF1664 PF07889.7 KFM05971.1 - 0.25 11.1 45.9 0.079 12.7 0.8 7.0 1 1 5 6 6 6 0 Protein of unknown function (DUF1664) Occludin_ELL PF07303.8 KFM05971.1 - 0.41 11.3 26.3 0.089 13.5 1.3 5.5 1 1 2 5 5 5 0 Occludin homology domain COG2 PF06148.6 KFM05971.1 - 0.56 10.0 40.8 0.29 11.0 2.3 6.5 1 1 6 7 7 7 0 COG (conserved oligomeric Golgi) complex component, COG2 CCD PF07860.6 KFM05971.1 - 0.68 9.4 2.6 30 4.0 0.1 3.3 3 1 0 3 3 3 0 WisP family C-Terminal Region Laminin_I PF06008.9 KFM05971.1 - 0.96 8.7 43.0 0.17 11.1 5.2 4.9 1 1 3 4 4 4 0 Laminin Domain I Spc7 PF08317.6 KFM05971.1 - 2.4 6.7 54.6 1.8 7.1 1.7 4.6 1 1 4 5 5 5 0 Spc7 kinetochore protein Fez1 PF06818.10 KFM05971.1 - 4.3 7.2 36.8 1.4 8.8 0.5 3.9 1 1 2 3 3 3 0 Fez1 APG6 PF04111.7 KFM05971.1 - 4.5 6.2 47.1 0.035 13.1 9.6 4.1 1 1 4 5 5 5 0 Autophagy protein Apg6 DUF4164 PF13747.1 KFM05971.1 - 5.8 7.1 35.2 14 5.8 1.1 7.1 2 2 4 7 7 7 0 Domain of unknown function (DUF4164) NPV_P10 PF05531.7 KFM05971.1 - 6.3 7.1 41.9 0.15 12.3 1.7 7.3 1 1 4 6 6 5 0 Nucleopolyhedrovirus P10 protein TMP_2 PF06791.8 KFM05971.1 - 7.1 6.1 16.3 0.082 12.5 0.6 4.0 1 1 2 4 4 4 0 Prophage tail length tape measure protein Tcp11 PF05794.8 KFM05972.1 - 1e-132 443.0 2.7 1.3e-132 442.7 1.9 1.1 1 0 0 1 1 1 1 T-complex protein 11 DUF1451 PF07295.6 KFM05972.1 - 0.026 14.3 1.0 0.065 13.0 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) RAP1 PF07218.6 KFM05972.1 - 0.8 7.7 4.8 1.7 6.6 3.3 1.5 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RNA_pol_Rpb2_6 PF00562.23 KFM05973.1 - 3.4e-125 417.8 0.0 2.1e-124 415.2 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KFM05973.1 - 2.9e-54 183.0 1.8 3.9e-54 182.6 0.7 1.7 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 KFM05973.1 - 9.2e-32 109.1 0.2 3.7e-31 107.2 0.1 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 KFM05973.1 - 5.8e-28 97.6 1.6 6.6e-28 97.4 0.4 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 KFM05973.1 - 5.9e-23 80.3 1.0 8.2e-22 76.7 0.0 2.7 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 KFM05973.1 - 5.4e-20 70.9 0.2 1.6e-19 69.4 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 KFM05973.1 - 1.5e-13 50.5 2.3 1.5e-13 50.5 1.6 2.3 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 5 RFX_DNA_binding PF02257.10 KFM05974.1 - 1e-34 118.4 0.0 4.4e-34 116.4 0.0 2.1 2 0 0 2 2 2 1 RFX DNA-binding domain Pox_D5 PF03288.11 KFM05974.1 - 9e-05 22.6 0.0 0.00024 21.2 0.0 1.7 1 0 0 1 1 1 1 Poxvirus D5 protein-like Ric8 PF10165.4 KFM05975.1 - 5e-140 467.2 2.6 6.2e-140 466.9 1.8 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn UPF0444 PF15475.1 KFM05976.1 - 1.3e-46 156.5 12.9 1.4e-46 156.4 9.0 1.0 1 0 0 1 1 1 1 Transmembrane protein C12orf23, UPF0444 Dicistro_VP4 PF11492.3 KFM05976.1 - 0.3 11.1 4.8 1.1 9.3 1.8 2.5 2 2 0 2 2 2 0 Cricket paralysis virus, VP4 mTERF PF02536.9 KFM05977.1 - 2.2e-19 69.2 6.6 2.9e-19 68.8 4.6 1.1 1 0 0 1 1 1 1 mTERF RRF_GI PF12614.3 KFM05977.1 - 0.068 12.9 1.0 0.22 11.3 0.7 1.8 1 0 0 1 1 1 0 Ribosome recycling factor DUF2795 PF11387.3 KFM05977.1 - 0.088 12.6 0.1 2.1 8.2 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2795) HTH_11 PF08279.7 KFM05977.1 - 0.091 12.4 0.1 0.35 10.5 0.0 2.1 1 0 0 1 1 1 0 HTH domain priB_priC PF07445.7 KFM05977.1 - 0.094 12.1 2.1 7.7 5.9 0.2 2.4 2 0 0 2 2 2 0 Primosomal replication protein priB and priC FAD_binding_7 PF03441.9 KFM05978.1 - 1.1e-105 352.8 0.1 1.4e-105 352.5 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 KFM05978.1 - 4.2e-09 36.3 0.0 9.3e-09 35.2 0.0 1.6 2 0 0 2 2 2 1 DNA photolyase Ank PF00023.25 KFM05979.1 - 5.1e-27 92.2 1.1 9.6e-10 37.7 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 KFM05979.1 - 1.3e-26 92.7 0.1 2.5e-13 50.1 0.0 3.6 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) BTB PF00651.26 KFM05979.1 - 2.3e-23 82.3 0.3 1.2e-21 76.7 0.1 3.3 2 1 1 3 3 3 1 BTB/POZ domain Ank_3 PF13606.1 KFM05979.1 - 4.6e-19 66.6 1.2 1.4e-05 24.8 0.0 5.7 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 KFM05979.1 - 6.3e-18 64.7 0.0 2e-05 24.9 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM05979.1 - 8.2e-18 64.0 0.5 0.00014 21.9 0.0 4.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) BACK PF07707.10 KFM05979.1 - 0.00056 19.6 1.0 0.0024 17.6 0.0 2.4 2 0 0 2 2 2 1 BTB And C-terminal Kelch WD40 PF00400.27 KFM05980.1 - 5.3e-23 80.0 7.5 4e-08 32.8 0.2 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat PQQ_3 PF13570.1 KFM05980.1 - 0.1 12.9 0.0 0.41 10.9 0.0 2.1 1 0 0 1 1 1 0 PQQ-like domain zf-H2C2_2 PF13465.1 KFM05981.1 - 1.7e-28 97.4 54.5 4.1e-08 33.1 0.6 8.5 8 0 0 8 8 8 6 Zinc-finger double domain zf-C2H2 PF00096.21 KFM05981.1 - 6.3e-21 73.3 65.9 2.9e-05 24.1 1.2 8.4 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM05981.1 - 8.5e-17 60.1 57.8 0.00085 19.4 0.6 8.3 8 0 0 8 8 8 5 C2H2-type zinc finger zf-met PF12874.2 KFM05981.1 - 7.8e-07 29.0 44.5 0.00034 20.7 0.8 7.6 7 0 0 7 7 7 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFM05981.1 - 6.2e-05 23.0 51.5 0.025 14.7 0.1 7.7 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding PyrI_C PF02748.10 KFM05981.1 - 0.01 15.2 0.3 0.01 15.2 0.2 4.4 2 1 3 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_6 PF13912.1 KFM05981.1 - 0.02 14.7 0.4 0.02 14.7 0.3 7.0 8 0 0 8 8 7 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KFM05981.1 - 0.05 13.8 38.7 0.068 13.4 0.4 7.0 6 0 0 6 6 6 0 C2H2-type zinc-finger domain Ecl1 PF12855.2 KFM05981.1 - 1.1 8.6 6.6 8.1 5.8 0.1 4.0 4 0 0 4 4 4 0 Life-span regulatory factor zf-C2H2_2 PF12756.2 KFM05981.1 - 1.6 8.8 37.8 6.3 6.9 7.2 6.0 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) Mu-like_Com PF10122.4 KFM05981.1 - 3.2 6.9 12.0 1.3 8.1 4.6 3.0 2 1 0 2 2 2 0 Mu-like prophage protein Com zf-met2 PF12907.2 KFM05981.1 - 8.5 6.4 20.7 8.4 6.4 0.1 5.5 5 1 0 5 5 5 0 Zinc-binding HLH PF00010.21 KFM05982.1 - 1.3e-17 63.2 1.8 2e-17 62.5 1.2 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Muted PF14942.1 KFM05982.1 - 0.098 12.5 0.1 0.13 12.1 0.1 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Sbi-IV PF11621.3 KFM05982.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 C3 binding domain 4 of IgG-bind protein SBI RtcB PF01139.12 KFM05983.1 - 1.5e-138 462.3 0.6 1.7e-138 462.1 0.4 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Cu-oxidase_4 PF02578.10 KFM05983.1 - 0.047 12.7 0.1 0.13 11.3 0.1 1.6 2 0 0 2 2 2 0 Multi-copper polyphenol oxidoreductase laccase LBP_BPI_CETP_C PF02886.12 KFM05984.1 - 3e-40 137.9 0.1 3.8e-40 137.6 0.1 1.0 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP_C PF02886.12 KFM05985.1 - 2.3e-45 154.6 0.2 2.6e-44 151.2 0.0 2.3 3 0 0 3 3 3 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.20 KFM05985.1 - 1.8e-27 95.7 0.4 9.4e-27 93.3 0.0 2.2 3 0 0 3 3 3 1 LBP / BPI / CETP family, N-terminal domain Cytochrom_C1 PF02167.10 KFM05985.1 - 0.064 12.9 0.0 0.099 12.2 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C1 family PI31_Prot_N PF11566.3 KFM05986.1 - 4.9e-22 78.1 0.0 7.4e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal F-box-like PF12937.2 KFM05986.1 - 1.1e-10 41.0 2.7 2.4e-10 39.9 1.9 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFM05986.1 - 1.5e-05 24.5 1.4 3.2e-05 23.4 1.0 1.6 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.6 KFM05986.1 - 0.013 15.8 0.4 0.025 14.9 0.3 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Mito_fiss_reg PF05308.6 KFM05986.1 - 3.9 6.7 11.9 0.076 12.3 1.1 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator Synapsin_C PF02750.9 KFM05987.1 - 3.8e-125 414.7 0.3 5e-125 414.3 0.2 1.1 1 0 0 1 1 1 1 Synapsin, ATP binding domain Synapsin PF02078.11 KFM05987.1 - 2.2e-46 156.2 0.1 5e-46 155.1 0.1 1.6 1 0 0 1 1 1 1 Synapsin, N-terminal domain RimK PF08443.6 KFM05987.1 - 5.5e-07 29.2 0.0 1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain TIMP PF00965.12 KFM05988.1 - 4.3e-65 218.7 8.3 5.2e-65 218.4 5.7 1.1 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase NTR PF01759.16 KFM05988.1 - 0.00025 20.5 1.0 0.00047 19.6 0.7 1.5 1 0 0 1 1 1 1 UNC-6/NTR/C345C module Glyco_transf_49 PF13896.1 KFM05989.1 - 6.3e-52 176.6 2.0 6.4e-42 143.7 1.0 2.3 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_transf_8 PF01501.15 KFM05989.1 - 7.9e-21 74.5 0.4 1.8e-20 73.3 0.3 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_tranf_2_2 PF10111.4 KFM05989.1 - 0.0021 17.2 0.0 0.0071 15.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Mto2_bdg PF12808.2 KFM05989.1 - 0.33 11.0 5.3 0.13 12.4 1.5 2.0 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region WD40_alt PF14077.1 KFM05989.1 - 5 6.8 6.3 16 5.2 4.4 1.8 1 0 0 1 1 1 0 Alternative WD40 repeat motif Ferritin PF00210.19 KFM05990.1 - 8.5e-18 64.4 0.2 9.3e-18 64.3 0.2 1.0 1 0 0 1 1 1 1 Ferritin-like domain WaaY PF06176.6 KFM05990.1 - 0.11 11.6 0.0 0.13 11.4 0.0 1.0 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) zf-H2C2_2 PF13465.1 KFM05991.1 - 1.1e-87 284.3 78.5 9.6e-11 41.4 0.5 12.8 13 0 0 13 13 13 11 Zinc-finger double domain zf-C2H2 PF00096.21 KFM05991.1 - 3.5e-79 256.5 83.4 8.5e-08 32.1 0.9 12.1 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM05991.1 - 3.9e-45 148.9 78.8 1.4e-05 25.0 1.1 12.1 12 0 0 12 12 12 12 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM05991.1 - 8e-37 124.0 56.6 7.3e-06 25.7 0.1 12.2 12 0 0 12 12 12 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM05991.1 - 7.7e-21 73.6 33.1 0.0026 17.8 0.0 11.1 12 0 0 12 12 11 5 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 KFM05991.1 - 2.5e-13 49.9 47.6 0.00011 22.2 0.8 8.0 4 3 2 7 7 7 3 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.5 KFM05991.1 - 5.1e-09 35.9 56.7 0.41 10.6 0.4 10.6 6 4 4 10 10 10 5 Zinc ribbon domain FYDLN_acid PF09538.5 KFM05991.1 - 1e-07 32.4 28.4 3.5 8.2 0.1 9.5 2 1 7 9 9 8 1 Protein of unknown function (FYDLN_acid) zf-met PF12874.2 KFM05991.1 - 1.5e-07 31.3 45.2 0.18 12.0 0.9 9.8 10 0 0 10 10 9 3 Zinc-finger of C2H2 type zf-RING_3 PF14369.1 KFM05991.1 - 2.5e-07 30.5 43.9 1 9.4 0.1 10.5 11 0 0 11 11 11 3 zinc-finger C1_4 PF07975.7 KFM05991.1 - 1.2e-06 28.4 37.4 0.42 10.6 1.7 8.5 2 2 7 9 9 9 3 TFIIH C1-like domain Zn_Tnp_IS1595 PF12760.2 KFM05991.1 - 3.8e-06 26.6 60.2 0.0017 18.1 1.1 7.6 3 2 5 8 8 8 3 Transposase zinc-ribbon domain C1_3 PF07649.7 KFM05991.1 - 1.1e-05 25.3 35.3 8.3 6.5 0.1 10.5 11 0 0 11 11 11 0 C1-like domain zf-ribbon_3 PF13248.1 KFM05991.1 - 1.5e-05 24.0 49.9 1.4 8.2 0.2 11.5 12 0 0 12 12 12 3 zinc-ribbon domain zinc_ribbon_5 PF13719.1 KFM05991.1 - 2.8e-05 23.5 43.1 1.7 8.2 0.1 10.7 11 1 0 11 11 11 2 zinc-ribbon domain MBD PF01429.14 KFM05991.1 - 0.00039 19.8 2.6 0.22 11.0 0.1 4.4 2 1 1 4 4 4 1 Methyl-CpG binding domain zinc_ribbon_4 PF13717.1 KFM05991.1 - 0.0004 19.9 42.6 3.7 7.3 0.1 10.5 11 1 0 11 11 11 1 zinc-ribbon domain Zn_ribbon_recom PF13408.1 KFM05991.1 - 0.00074 19.7 39.6 0.16 12.2 2.2 7.5 3 2 4 8 8 8 2 Recombinase zinc beta ribbon domain Prok-RING_1 PF14446.1 KFM05991.1 - 0.0014 18.2 30.9 14 5.4 0.0 10.4 12 0 0 12 12 11 0 Prokaryotic RING finger family 1 DUF164 PF02591.10 KFM05991.1 - 0.0018 18.0 34.5 0.56 10.0 1.0 9.1 10 0 0 10 10 9 2 Putative zinc ribbon domain CpXC PF14353.1 KFM05991.1 - 0.0025 17.7 39.3 4.4 7.2 0.0 9.9 6 3 0 8 8 7 0 CpXC protein XPA_N PF01286.13 KFM05991.1 - 0.0031 17.1 46.6 0.9 9.2 0.0 11.3 12 0 0 12 12 12 1 XPA protein N-terminal zf-AN1 PF01428.11 KFM05991.1 - 0.0032 17.3 44.3 2.9 7.8 0.1 11.1 9 1 2 11 11 11 1 AN1-like Zinc finger zf-BED PF02892.10 KFM05991.1 - 0.019 14.6 3.3 0.019 14.6 2.3 7.1 5 3 4 9 9 7 0 BED zinc finger zf-C2HC_2 PF13913.1 KFM05991.1 - 0.032 13.9 0.6 0.032 13.9 0.4 11.4 12 0 0 12 12 11 0 zinc-finger of a C2HC-type LIM PF00412.17 KFM05991.1 - 0.043 13.8 0.8 0.043 13.8 0.5 7.3 3 3 5 8 8 7 0 LIM domain DUF1610 PF07754.6 KFM05991.1 - 0.057 13.5 0.9 0.057 13.5 0.6 10.8 12 0 0 12 12 10 0 Domain of unknown function (DUF1610) GAGA PF09237.6 KFM05991.1 - 0.062 12.9 0.3 0.062 12.9 0.2 7.6 3 3 6 9 9 8 0 GAGA factor A2L_zn_ribbon PF08792.5 KFM05991.1 - 0.16 11.4 53.2 0.26 10.8 0.2 10.8 12 0 0 12 12 12 0 A2L zinc ribbon domain HypA PF01155.14 KFM05991.1 - 0.18 11.4 36.4 4.1 7.1 2.1 6.6 1 1 4 5 5 5 0 Hydrogenase expression/synthesis hypA family Elf1 PF05129.8 KFM05991.1 - 0.38 10.4 28.7 0.44 10.2 0.1 6.5 2 1 7 9 9 9 0 Transcription elongation factor Elf1 like BolA PF01722.13 KFM05991.1 - 0.63 10.0 4.8 44 4.1 0.0 4.2 4 2 1 5 5 5 0 BolA-like protein zf-ISL3 PF14690.1 KFM05991.1 - 1 9.4 56.3 1 9.4 0.1 11.2 11 1 1 12 12 10 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-trcl PF13451.1 KFM05991.1 - 2.1 8.0 41.8 8.6 6.0 0.1 10.0 10 1 0 10 10 10 0 Probable zinc-binding domain YhfH PF14149.1 KFM05991.1 - 4.8 7.0 31.2 17 5.2 0.0 9.2 10 0 0 10 10 9 0 YhfH-like protein TerY-C PF15616.1 KFM05991.1 - 7.8 6.4 37.7 0.32 10.9 0.8 5.8 2 2 3 6 6 6 0 TerY-C metal binding domain Sad1_UNC PF07738.8 KFM05993.1 - 8.2e-33 113.0 0.0 9e-33 112.9 0.0 1.0 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal RasGEF PF00617.14 KFM05994.1 - 4.2e-52 176.6 1.5 6.2e-52 176.0 0.2 1.8 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 KFM05994.1 - 5.4e-17 61.8 0.8 1.4e-16 60.4 0.1 2.1 2 0 0 2 2 2 1 RasGEF N-terminal motif Pkinase PF00069.20 KFM05995.1 - 1.9e-68 230.4 0.4 1.6e-67 227.3 0.0 2.4 3 0 0 3 3 3 1 Protein kinase domain cNMP_binding PF00027.24 KFM05995.1 - 2.5e-39 132.9 0.2 7e-20 70.6 0.1 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.12 KFM05995.1 - 3.7e-34 117.9 0.0 5.9e-33 114.0 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM05995.1 - 2.5e-05 23.3 0.0 5.1e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like ATG16 PF08614.6 KFM05995.1 - 7.1e-05 22.7 6.9 0.00018 21.4 4.8 1.6 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) APH PF01636.18 KFM05995.1 - 0.0077 15.9 0.1 0.03 14.0 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family IncA PF04156.9 KFM05995.1 - 0.013 15.0 6.4 0.042 13.4 4.4 1.8 1 0 0 1 1 1 0 IncA protein DUF3552 PF12072.3 KFM05995.1 - 0.027 13.6 6.3 0.065 12.4 4.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Reo_sigmaC PF04582.7 KFM05995.1 - 0.23 10.6 0.6 0.45 9.6 0.4 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein SlyX PF04102.7 KFM05995.1 - 0.51 10.7 6.0 0.55 10.6 2.9 2.0 1 1 0 1 1 1 0 SlyX RVT_1 PF00078.22 KFM05996.1 - 6.5e-15 55.0 0.0 1.1e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DZF PF07528.9 KFM05997.1 - 1.6e-105 351.9 0.0 2.7e-105 351.2 0.0 1.4 1 0 0 1 1 1 1 DZF domain dsrm PF00035.20 KFM05997.1 - 6e-28 97.2 0.2 1.1e-13 51.5 0.1 2.7 2 0 0 2 2 2 2 Double-stranded RNA binding motif DND1_DSRM PF14709.1 KFM05997.1 - 2.5e-07 30.8 0.1 0.043 14.1 0.0 2.9 2 0 0 2 2 2 2 double strand RNA binding domain from DEAD END PROTEIN 1 RNA_polI_A14 PF08203.6 KFM05997.1 - 0.034 14.3 0.2 0.091 13.0 0.2 1.8 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 Choline_transpo PF04515.7 KFM05998.1 - 2e-129 431.1 48.5 2.8e-129 430.6 22.7 3.0 3 0 0 3 3 3 3 Plasma-membrane choline transporter Ran_BP1 PF00638.13 KFM05999.1 - 7.7e-14 51.7 0.0 1.4e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain FAM101 PF15068.1 KFM05999.1 - 7.4 5.9 11.4 0.26 10.6 1.2 2.9 1 1 2 3 3 3 0 FAM101 family PRY PF13765.1 KFM06000.1 - 1.6e-22 78.7 0.3 2.8e-22 77.9 0.2 1.4 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.23 KFM06000.1 - 6.4e-19 68.2 0.1 8.1e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 SPRY domain Opiods_neuropep PF01160.13 KFM06000.1 - 0.0017 18.0 0.0 0.0033 17.1 0.0 1.4 1 0 0 1 1 1 1 Vertebrate endogenous opioids neuropeptide PRY PF13765.1 KFM06001.1 - 1.4e-21 75.7 0.0 2.1e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.23 KFM06001.1 - 4.8e-14 52.5 0.0 6.4e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 SPRY domain UFD1 PF03152.9 KFM06001.1 - 0.13 11.4 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 PRY PF13765.1 KFM06002.1 - 3.7e-22 77.6 0.1 6.1e-22 76.8 0.1 1.4 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.23 KFM06002.1 - 1.1e-15 57.8 0.0 1.6e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 SPRY domain Opiods_neuropep PF01160.13 KFM06002.1 - 0.1 12.4 0.4 0.16 11.7 0.3 1.3 1 0 0 1 1 1 0 Vertebrate endogenous opioids neuropeptide DUF4222 PF13973.1 KFM06002.1 - 0.25 10.7 1.0 0.44 9.9 0.1 1.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4222) RINGv PF12906.2 KFM06003.1 - 6.9e-15 54.8 7.4 6.9e-15 54.8 5.2 2.9 4 0 0 4 4 4 1 RING-variant domain Vpu PF00558.14 KFM06003.1 - 0.0087 15.5 0.2 0.016 14.7 0.1 1.3 1 0 0 1 1 1 1 Vpu protein zf-Apc11 PF12861.2 KFM06003.1 - 0.035 13.9 0.9 0.035 13.9 0.6 2.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 KFM06003.1 - 0.041 13.8 3.7 0.15 12.1 2.6 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KFM06003.1 - 0.21 11.5 5.6 0.4 10.6 1.6 2.7 2 1 1 3 3 3 0 FANCL C-terminal domain zf-rbx1 PF12678.2 KFM06003.1 - 2.2 8.4 7.0 8.5 6.5 3.2 2.6 2 1 0 2 2 2 0 RING-H2 zinc finger zf-RING_2 PF13639.1 KFM06003.1 - 4 7.3 10.5 0.94 9.3 4.4 2.2 2 0 0 2 2 2 0 Ring finger domain Ras PF00071.17 KFM06004.1 - 3.1e-63 211.9 0.1 3.7e-63 211.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM06004.1 - 1.1e-20 74.3 0.0 1.7e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM06004.1 - 2.1e-12 46.5 0.1 2.7e-12 46.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFM06004.1 - 9e-08 32.0 0.1 1.8e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KFM06004.1 - 6.8e-07 29.4 0.1 2.5e-06 27.6 0.0 2.0 2 1 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 KFM06004.1 - 1.4e-05 24.6 0.1 2.6e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFM06004.1 - 0.0012 17.9 0.1 0.0024 17.0 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.1 KFM06004.1 - 0.0027 17.6 0.1 0.0069 16.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 KFM06004.1 - 0.0028 16.7 0.1 0.0044 16.1 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 KFM06004.1 - 0.0034 16.5 0.0 0.0098 15.0 0.0 1.8 2 1 1 3 3 3 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KFM06004.1 - 0.0074 16.2 0.5 0.04 13.8 0.2 2.2 1 1 1 2 2 2 1 AAA ATPase domain SRPRB PF09439.5 KFM06004.1 - 0.019 14.1 0.0 0.045 12.9 0.0 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 KFM06004.1 - 0.025 14.8 0.4 0.042 14.1 0.3 1.8 1 1 0 1 1 1 0 ABC transporter FeoB_N PF02421.13 KFM06004.1 - 0.031 13.5 0.2 0.15 11.3 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B YtzH PF14165.1 KFM06004.1 - 0.035 14.3 0.0 0.2 11.9 0.0 2.0 2 0 0 2 2 2 0 YtzH-like protein PduV-EutP PF10662.4 KFM06004.1 - 0.11 12.0 0.0 0.28 10.6 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 KFM06004.1 - 0.12 12.6 0.4 0.83 9.9 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_21 PF13304.1 KFM06004.1 - 0.39 10.6 2.6 0.98 9.3 1.8 1.9 1 1 0 1 1 1 0 AAA domain Fibrinogen_C PF00147.13 KFM06005.1 - 1.6e-62 211.2 1.0 3.3e-62 210.1 0.7 1.5 1 1 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DivIC PF04977.10 KFM06005.1 - 0.28 10.6 6.1 0.57 9.7 4.3 1.4 1 0 0 1 1 1 0 Septum formation initiator KN_motif PF12075.3 KFM06006.1 - 2.3e-19 68.9 0.2 3.9e-19 68.1 0.1 1.4 1 0 0 1 1 1 1 KN motif Phage_GP20 PF06810.6 KFM06006.1 - 0.015 14.7 0.7 0.046 13.1 0.1 1.9 2 0 0 2 2 2 0 Phage minor structural protein GP20 Ank_2 PF12796.2 KFM06007.1 - 8.4e-27 93.3 12.5 1.9e-18 66.5 0.5 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFM06007.1 - 2.5e-24 85.1 5.3 3.4e-12 46.5 0.0 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 KFM06007.1 - 4e-23 80.0 10.0 3.5e-10 39.1 0.1 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 KFM06007.1 - 7.3e-21 73.7 10.0 5.3e-12 45.5 0.2 4.7 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM06007.1 - 3.6e-16 57.6 4.2 2.8e-06 27.0 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeat CDC45 PF02724.9 KFM06007.1 - 0.38 8.7 3.6 0.51 8.3 2.5 1.1 1 0 0 1 1 1 0 CDC45-like protein CI-B14_5a PF07347.7 KFM06008.1 - 2.3e-20 72.1 0.4 2.5e-20 72.0 0.2 1.0 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Col_cuticle_N PF01484.12 KFM06009.1 - 5 6.8 6.3 7.7 6.2 4.4 1.3 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain hSH3 PF14603.1 KFM06011.1 - 9.4e-15 54.3 0.0 1.2e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Helically-extended SH3 domain SH3_2 PF07653.12 KFM06011.1 - 0.00053 19.4 0.0 0.00053 19.4 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KFM06011.1 - 0.0014 18.2 0.0 0.0019 17.7 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM06011.1 - 0.05 12.9 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 SH3 domain SDF PF00375.13 KFM06012.1 - 4.3e-127 424.1 27.5 4.8e-127 423.9 19.1 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family RRM_1 PF00076.17 KFM06013.1 - 4.2e-62 205.7 0.1 2.5e-19 68.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM06013.1 - 5.9e-42 141.5 0.1 2.2e-12 46.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM06013.1 - 1.5e-30 104.7 0.2 7.7e-11 41.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFM06013.1 - 0.00095 18.9 0.0 0.1 12.4 0.0 2.5 1 1 1 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 KFM06013.1 - 0.0095 15.6 0.0 0.41 10.4 0.0 2.8 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif E2 PF08199.6 KFM06013.1 - 0.043 13.4 0.0 0.13 11.8 0.0 1.8 1 0 0 1 1 1 0 Bacteriophage E2-like protein Pkinase_Tyr PF07714.12 KFM06015.1 - 6.4e-88 294.1 0.0 8.4e-88 293.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM06015.1 - 1.4e-45 155.5 0.0 2.3e-45 154.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 KFM06015.1 - 4.2e-21 74.5 0.0 9.5e-21 73.3 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.23 KFM06015.1 - 4.7e-09 35.4 0.0 9.4e-09 34.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFM06015.1 - 2.4e-06 27.0 0.0 6.3e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFM06015.1 - 0.00013 21.4 0.0 0.00027 20.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain APH PF01636.18 KFM06015.1 - 0.0005 19.8 0.0 0.0019 17.9 0.0 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KFM06015.1 - 0.015 14.2 0.0 0.048 12.6 0.0 1.8 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.17 KFM06015.1 - 0.033 13.5 0.1 0.07 12.4 0.0 1.5 1 0 0 1 1 1 0 RIO1 family SH3_3 PF08239.6 KFM06015.1 - 0.16 12.1 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain Homeobox PF00046.24 KFM06016.1 - 1.4e-24 85.4 4.6 2.3e-24 84.7 3.2 1.4 1 0 0 1 1 1 1 Homeobox domain OAR PF03826.12 KFM06016.1 - 2e-11 43.0 0.5 4.4e-11 41.9 0.3 1.6 1 0 0 1 1 1 1 OAR domain Peptidase_C14 PF00656.17 KFM06017.1 - 1.1e-17 64.5 0.0 1.5e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Ribosomal_L37 PF08561.5 KFM06018.1 - 1.5e-21 75.7 0.1 1.7e-21 75.6 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 PDZ PF00595.19 KFM06019.1 - 2.6e-43 146.0 4.3 2.5e-15 56.4 0.1 3.4 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM06019.1 - 3.1e-19 68.6 0.9 9.8e-08 31.7 0.0 3.5 3 0 0 3 3 3 3 PDZ domain SH3_2 PF07653.12 KFM06019.1 - 1.3e-10 40.5 0.0 3.4e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain Guanylate_kin PF00625.16 KFM06019.1 - 3.2e-09 36.4 0.0 1.1e-08 34.7 0.0 1.8 1 1 1 2 2 2 1 Guanylate kinase Tricorn_PDZ PF14685.1 KFM06019.1 - 1.6e-05 24.5 0.1 0.04 13.7 0.0 2.7 2 0 0 2 2 2 2 Tricorn protease PDZ domain SH3_1 PF00018.23 KFM06019.1 - 0.0011 18.3 0.0 0.0029 16.9 0.0 1.8 1 0 0 1 1 1 1 SH3 domain PIP5K PF01504.13 KFM06020.1 - 3.8e-79 265.3 0.0 5.1e-79 264.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Toxin_33 PF08121.6 KFM06020.1 - 0.16 11.5 0.8 0.32 10.6 0.5 1.5 1 0 0 1 1 1 0 Waglerin family PDZ PF00595.19 KFM06022.1 - 3.4e-07 30.3 0.0 5.4e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) CBM_X PF06204.6 KFM06022.1 - 0.15 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative carbohydrate binding domain HMG_box PF00505.14 KFM06023.1 - 1.5e-19 70.0 1.0 1.5e-19 70.0 0.7 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFM06023.1 - 4.1e-13 49.4 0.3 1.4e-12 47.7 0.2 1.9 1 0 0 1 1 1 1 HMG-box domain OmpH PF03938.9 KFM06023.1 - 0.038 13.9 14.7 0.069 13.0 2.6 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) IncA PF04156.9 KFM06023.1 - 0.14 11.6 15.5 0.036 13.6 3.1 2.2 2 0 0 2 2 2 0 IncA protein Caudo_TAP PF02413.12 KFM06023.1 - 1.5 8.9 7.8 0.33 11.1 0.8 2.3 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein UPF0242 PF06785.6 KFM06023.1 - 2.2 6.8 13.8 0.57 8.8 4.8 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) DUF724 PF05266.9 KFM06023.1 - 3.1 7.3 19.0 0.23 11.0 5.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) APG6 PF04111.7 KFM06023.1 - 4.4 6.2 19.9 2.3 7.1 6.0 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 HemX PF04375.9 KFM06023.1 - 4.5 5.7 10.5 0.21 10.1 2.4 1.9 2 0 0 2 2 2 0 HemX MFS_2 PF13347.1 KFM06024.1 - 7.8e-22 77.2 9.9 7.8e-22 77.2 6.8 1.6 2 0 0 2 2 2 1 MFS/sugar transport protein DDE_Tnp_4 PF13359.1 KFM06026.1 - 8.9e-28 96.8 0.0 1.2e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 KFM06026.1 - 6.5e-12 45.2 0.0 9e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein HTH_Tnp_4 PF13613.1 KFM06026.1 - 1.6e-07 30.7 0.0 3.4e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease Gemini_AL3 PF01407.12 KFM06026.1 - 0.042 13.3 0.0 0.15 11.4 0.0 1.9 2 0 0 2 2 2 0 Geminivirus AL3 protein HEAT_2 PF13646.1 KFM06027.1 - 7.8e-24 83.7 0.1 5.9e-15 55.3 0.0 2.0 1 1 1 2 2 2 2 HEAT repeats HEAT_PBS PF03130.11 KFM06027.1 - 4.4e-15 54.5 0.6 3.1e-05 24.0 0.0 3.3 3 0 0 3 3 3 3 PBS lyase HEAT-like repeat HEAT PF02985.17 KFM06027.1 - 0.0002 21.1 0.1 0.014 15.3 0.0 3.2 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 KFM06027.1 - 0.043 14.3 0.1 0.2 12.2 0.0 2.2 1 1 0 1 1 1 0 HEAT-like repeat Membr_traf_MHD PF10540.4 KFM06028.1 - 2.4e-57 192.5 1.8 4.7e-57 191.6 1.3 1.5 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 KFM06028.1 - 3e-10 39.8 0.1 5.9e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 C2 domain ASC PF00858.19 KFM06029.1 - 2.5e-35 122.0 0.0 2.7e-35 121.8 0.0 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Ank_2 PF12796.2 KFM06030.1 - 3.5e-61 203.5 12.9 1.1e-20 73.7 0.0 3.9 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KFM06030.1 - 1.2e-43 144.8 16.6 2.5e-07 30.1 0.0 8.4 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.1 KFM06030.1 - 7.4e-34 115.5 8.3 1.1e-06 29.0 0.1 7.7 4 1 3 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM06030.1 - 1.7e-33 113.8 15.8 8.5e-11 41.7 0.3 5.6 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM06030.1 - 1.9e-29 98.7 10.0 3.6e-05 23.6 0.1 8.0 8 0 0 8 8 8 7 Ankyrin repeat SOCS_box PF07525.11 KFM06030.1 - 7.6e-09 35.2 6.5 1.9e-08 34.0 4.5 1.7 1 0 0 1 1 1 1 SOCS box ocr PF08684.5 KFM06030.1 - 0.16 11.9 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 DNA mimic ocr Histone PF00125.19 KFM06031.1 - 3.5e-25 87.9 0.2 4.5e-25 87.5 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFM06031.1 - 1.4e-06 28.2 0.1 2.5e-06 27.4 0.0 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KFM06031.1 - 0.0054 16.9 0.0 0.0089 16.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1931 PF09123.6 KFM06031.1 - 0.015 15.2 0.0 0.054 13.4 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1931) ABC_tran PF00005.22 KFM06032.1 - 2.6e-47 160.5 0.0 1.2e-24 87.1 0.0 2.8 3 0 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 KFM06032.1 - 1.5e-20 72.8 3.7 1.5e-20 72.8 2.6 2.6 4 0 0 4 4 2 1 ABC transporter AAA_21 PF13304.1 KFM06032.1 - 5.3e-18 66.0 0.3 3e-06 27.4 0.0 4.2 3 1 1 4 4 4 3 AAA domain AAA_29 PF13555.1 KFM06032.1 - 9.2e-07 28.2 0.4 0.00082 18.8 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 KFM06032.1 - 9.3e-07 28.2 0.6 0.47 9.6 0.0 3.8 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KFM06032.1 - 2.7e-06 28.1 0.7 0.012 16.4 0.0 3.2 3 1 0 3 3 2 2 AAA domain Miro PF08477.8 KFM06032.1 - 2.8e-05 24.5 0.0 0.42 11.1 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_16 PF13191.1 KFM06032.1 - 4.2e-05 23.6 0.0 0.18 11.7 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 KFM06032.1 - 4.5e-05 22.7 0.0 0.0096 15.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KFM06032.1 - 0.00016 21.5 0.0 0.062 13.2 0.0 2.8 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_33 PF13671.1 KFM06032.1 - 0.00019 21.3 0.1 0.1 12.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.1 KFM06032.1 - 0.00059 18.9 3.9 0.25 10.3 0.0 3.5 3 2 2 5 5 5 2 AAA ATPase domain AAA_23 PF13476.1 KFM06032.1 - 0.00086 19.6 9.2 0.023 15.0 0.0 3.4 4 0 0 4 4 3 2 AAA domain NACHT PF05729.7 KFM06032.1 - 0.00098 18.8 0.2 0.31 10.6 0.0 2.8 3 0 0 3 3 2 1 NACHT domain AAA_22 PF13401.1 KFM06032.1 - 0.0016 18.6 0.1 0.5 10.5 0.1 3.1 2 1 0 2 2 2 1 AAA domain Rop PF01815.11 KFM06032.1 - 0.0026 17.1 3.1 0.4 10.1 0.1 3.0 2 0 0 2 2 2 1 Rop protein AAA_14 PF13173.1 KFM06032.1 - 0.003 17.4 0.0 0.79 9.6 0.0 3.1 3 0 0 3 3 2 1 AAA domain SbcCD_C PF13558.1 KFM06032.1 - 0.0055 16.5 0.0 0.16 11.9 0.0 2.7 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 KFM06032.1 - 0.0069 16.6 0.8 0.16 12.3 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KFM06032.1 - 0.0077 16.2 0.0 0.42 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KFM06032.1 - 0.014 15.6 0.1 1.4 9.1 0.1 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KFM06032.1 - 0.014 14.8 0.3 1.7 8.0 0.0 2.9 2 1 1 3 3 3 0 AAA domain NB-ARC PF00931.17 KFM06032.1 - 0.026 13.3 0.0 4.1 6.1 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_10 PF12846.2 KFM06032.1 - 0.033 13.6 4.6 0.083 12.3 0.0 3.2 4 0 0 4 4 4 0 AAA-like domain ArgK PF03308.11 KFM06032.1 - 0.037 12.8 3.0 3 6.5 0.0 2.9 3 0 0 3 3 3 0 ArgK protein AAA_5 PF07728.9 KFM06032.1 - 0.041 13.6 0.2 4.4 7.0 0.1 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 KFM06032.1 - 0.042 14.0 0.0 0.59 10.3 0.0 2.4 2 0 0 2 2 2 0 RNA helicase MobB PF03205.9 KFM06032.1 - 0.052 13.2 0.3 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 KFM06032.1 - 0.055 13.2 0.1 0.18 11.5 0.0 2.0 3 0 0 3 3 1 0 Dynamin family AAA_30 PF13604.1 KFM06032.1 - 0.061 12.9 0.0 0.62 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KFM06032.1 - 0.067 12.2 0.0 0.2 10.7 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.1 KFM06032.1 - 0.28 10.7 1.5 2.3 7.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain CHGN PF05679.11 KFM06033.1 - 3.2e-171 570.4 0.1 3.9e-171 570.1 0.1 1.1 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.11 KFM06033.1 - 4.3e-11 42.5 0.1 8.2e-11 41.5 0.1 1.4 1 0 0 1 1 1 1 Fringe-like SWIB PF02201.13 KFM06035.1 - 2.4e-25 87.9 0.1 6.4e-25 86.6 0.1 1.8 1 0 0 1 1 1 1 SWIB/MDM2 domain DNA_mis_repair PF01119.14 KFM06036.1 - 1.7e-24 85.5 0.1 1.1e-23 82.9 0.0 2.4 3 0 0 3 3 3 1 DNA mismatch repair protein, C-terminal domain HMG_box PF00505.14 KFM06036.1 - 8.1e-14 51.6 1.5 3.2e-13 49.7 1.0 2.0 1 0 0 1 1 1 1 HMG (high mobility group) box HATPase_c_3 PF13589.1 KFM06036.1 - 4.4e-13 49.0 0.2 1e-12 47.8 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KFM06036.1 - 3.9e-11 42.6 0.1 1e-10 41.3 0.1 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HMG_box_2 PF09011.5 KFM06036.1 - 5.4e-11 42.6 1.1 1.3e-10 41.4 0.8 1.6 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 KFM06036.1 - 0.0015 18.2 0.9 0.0038 16.9 0.6 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box 5 TGFb_propeptide PF00688.13 KFM06037.1 - 2.5e-48 164.4 0.0 3.3e-48 164.0 0.0 1.1 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.15 KFM06037.1 - 2.7e-28 98.3 1.2 7.7e-28 96.8 0.8 1.8 1 0 0 1 1 1 1 Transforming growth factor beta like domain DUF4565 PF15127.1 KFM06039.1 - 5.2e-28 97.2 0.0 5.8e-28 97.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4565) ECH_C PF13766.1 KFM06040.1 - 1.2e-43 148.0 0.1 2.5e-43 146.9 0.1 1.6 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 KFM06040.1 - 2.4e-35 121.8 0.0 2.7e-33 115.1 0.0 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family Thioredox_DsbH PF03190.10 KFM06040.1 - 0.044 13.4 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 MFS_1 PF07690.11 KFM06041.1 - 1.2e-30 106.4 25.6 4.6e-17 61.7 8.1 3.5 2 2 1 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.2 KFM06041.1 - 1.4e-16 59.9 4.0 1.4e-16 59.9 2.7 2.9 4 0 0 4 4 4 1 MFS_1 like family MFS_2 PF13347.1 KFM06041.1 - 7.5e-13 47.6 8.9 2.7e-11 42.5 3.1 2.9 1 1 1 2 2 2 2 MFS/sugar transport protein Nuc_H_symport PF03825.11 KFM06041.1 - 6.2e-08 31.8 7.0 6.2e-08 31.8 4.9 3.5 3 1 0 3 3 3 1 Nucleoside H+ symporter LacY_symp PF01306.14 KFM06041.1 - 1.1e-06 27.4 18.6 0.0013 17.3 2.7 3.2 3 0 0 3 3 3 3 LacY proton/sugar symporter MFS_3 PF05977.8 KFM06041.1 - 7.1e-05 21.1 1.3 0.00049 18.3 0.4 2.1 2 0 0 2 2 2 1 Transmembrane secretion effector ATG22 PF11700.3 KFM06041.1 - 0.00028 19.5 20.4 0.12 10.8 0.3 3.1 3 0 0 3 3 3 3 Vacuole effluxer Atg22 like DUF3671 PF12420.3 KFM06041.1 - 0.18 11.8 2.4 0.39 10.7 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function OppC_N PF12911.2 KFM06041.1 - 1.2 8.5 12.9 1.1 8.7 0.0 3.9 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C OAD_gamma PF04277.8 KFM06041.1 - 2.6 8.4 7.1 6.7 7.1 0.0 3.9 4 0 0 4 4 4 0 Oxaloacetate decarboxylase, gamma chain DUF2215 PF10225.4 KFM06042.1 - 5.2e-79 265.2 5.1 6.9e-79 264.8 3.5 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2215) Kringle PF00051.13 KFM06042.1 - 0.31 11.1 3.1 4.5 7.4 0.0 2.8 2 1 0 2 2 2 0 Kringle domain NCD2 PF04905.8 KFM06043.1 - 4.1e-78 260.8 1.7 6.8e-78 260.1 1.2 1.3 1 0 0 1 1 1 1 NAB conserved region 2 (NCD2) Nab1 PF04902.7 KFM06043.1 - 6.7e-67 224.1 0.6 1.7e-66 222.8 0.4 1.7 1 0 0 1 1 1 1 Conserved region in Nab1 NCD1 PF04904.8 KFM06043.1 - 7.9e-46 153.7 0.1 1.3e-45 152.9 0.0 1.3 1 0 0 1 1 1 1 NAB conserved region 1 (NCD1) tRNA-synt_1b PF00579.20 KFM06043.1 - 0.51 9.4 2.5 2.9 6.9 0.1 2.4 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) Myosin_head PF00063.16 KFM06044.1 - 6.9e-251 834.1 2.7 1e-250 833.5 1.8 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 KFM06044.1 - 1.5e-41 141.8 4.3 1.7e-41 141.7 0.2 2.3 2 0 0 2 2 2 1 Myosin tail IQ PF00612.22 KFM06044.1 - 0.00032 20.0 0.6 0.00032 20.0 0.4 6.4 6 0 0 6 6 6 2 IQ calmodulin-binding motif AAA_22 PF13401.1 KFM06044.1 - 0.026 14.6 0.4 0.12 12.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KFM06044.1 - 0.03 15.1 2.6 0.1 13.4 0.0 3.4 4 1 0 4 4 4 0 AAA domain Hpr_kinase_C PF07475.7 KFM06044.1 - 0.03 13.6 1.0 1.1 8.5 0.0 2.6 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Sigma54_activat PF00158.21 KFM06044.1 - 0.066 12.6 0.0 0.88 9.0 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain tRNA_anti-codon PF01336.20 KFM06045.1 - 1.8e-07 30.8 0.1 2.2e-07 30.6 0.1 1.1 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Phage_BR0599 PF09356.5 KFM06045.1 - 0.0095 16.0 0.0 0.012 15.7 0.0 1.1 1 0 0 1 1 1 1 Phage conserved hypothetical protein BR0599 Kazal_2 PF07648.10 KFM06046.1 - 3.2e-17 62.1 17.4 1.6e-10 40.7 3.9 4.1 5 0 0 5 5 5 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 KFM06046.1 - 3e-14 52.7 25.8 1e-09 38.2 4.5 4.6 3 3 1 4 4 4 2 Kazal-type serine protease inhibitor domain hEGF PF12661.2 KFM06046.1 - 0.0011 18.9 3.4 0.0011 18.9 2.3 4.4 4 0 0 4 4 4 1 Human growth factor-like EGF Serglycin PF04360.7 KFM06046.1 - 0.053 13.2 0.1 0.096 12.4 0.1 1.4 1 0 0 1 1 1 0 Serglycin EphA2_TM PF14575.1 KFM06046.1 - 0.068 13.5 1.7 0.1 13.0 0.1 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Sof1 PF04158.9 KFM06048.1 - 2.2e-35 120.5 8.9 3.6e-35 119.8 6.1 1.3 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.27 KFM06048.1 - 1.3e-28 97.7 10.2 6.1e-06 25.9 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 KFM06048.1 - 8.6e-07 28.8 0.9 0.00058 19.6 0.0 3.6 2 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A Mito_carr PF00153.22 KFM06049.1 - 3.7e-65 215.6 3.3 4e-25 87.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Collagen PF01391.13 KFM06050.1 - 2.8e-07 29.9 6.9 4.7e-07 29.2 4.8 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Frizzled PF01534.12 KFM06051.1 - 2.8e-130 433.9 17.8 3.7e-130 433.5 12.3 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.17 KFM06051.1 - 5.4e-27 94.4 7.4 1.3e-26 93.2 5.1 1.7 1 0 0 1 1 1 1 Fz domain Folate_rec PF03024.9 KFM06051.1 - 0.0045 16.6 1.9 0.0045 16.6 1.3 1.7 2 0 0 2 2 2 1 Folate receptor family DUF4014 PF13198.1 KFM06051.1 - 0.019 15.3 0.3 0.33 11.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4014) RseC_MucC PF04246.7 KFM06051.1 - 0.44 10.1 0.0 0.44 10.1 0.0 2.8 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC DUF2514 PF10721.4 KFM06052.1 - 1.7 8.2 6.4 1.2 8.7 1.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2514) V-ATPase_C PF03223.10 KFM06053.1 - 1.4e-152 507.8 10.4 1.6e-152 507.7 7.2 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Orn_Arg_deC_N PF02784.11 KFM06054.1 - 8.2e-62 208.6 0.0 1e-61 208.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 KFM06054.1 - 9.5e-21 73.6 0.0 1.5e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain zf-H2C2_2 PF13465.1 KFM06055.1 - 1e-11 44.5 9.7 1.6e-07 31.3 1.4 4.6 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFM06055.1 - 1.8e-11 43.6 25.0 0.00061 19.9 2.1 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM06055.1 - 2.2e-09 37.0 19.4 0.0027 17.9 1.4 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger RRN7 PF11781.3 KFM06055.1 - 0.0075 15.7 2.9 0.59 9.6 0.1 2.5 2 0 0 2 2 2 2 RNA polymerase I-specific transcription initiation factor Rrn7 zf-TRAF PF02176.13 KFM06055.1 - 0.068 13.5 0.7 0.068 13.5 0.5 2.4 1 1 1 2 2 2 0 TRAF-type zinc finger zf-Di19 PF05605.7 KFM06055.1 - 0.79 9.8 10.0 0.25 11.5 0.9 3.0 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding HSP20 PF00011.16 KFM06056.1 - 9.9e-12 44.6 0.1 1.1e-11 44.4 0.1 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Ribonuc_red_sm PF00268.16 KFM06057.1 - 3.4e-123 410.1 0.6 4.1e-123 409.8 0.4 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain EF-hand_1 PF00036.27 KFM06058.1 - 2.4e-20 70.1 5.1 2.2e-07 29.6 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KFM06058.1 - 4.2e-20 71.6 1.1 1.1e-10 41.4 0.0 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KFM06058.1 - 1.6e-18 65.0 2.6 1e-06 27.8 0.1 4.7 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 KFM06058.1 - 2.5e-17 61.1 0.7 3.5e-06 26.4 0.1 4.5 4 1 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 KFM06058.1 - 1.1e-11 44.1 5.9 3.7e-06 26.4 0.2 4.3 1 1 3 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFM06058.1 - 3.1e-05 23.9 0.0 0.035 14.1 0.0 2.6 2 2 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFM06058.1 - 0.00065 19.4 0.3 0.12 12.1 0.0 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand CP2 PF04516.10 KFM06059.1 - 4.1e-85 284.6 3.4 6.5e-85 283.9 2.4 1.3 1 0 0 1 1 1 1 CP2 transcription factor 4F5 PF04419.9 KFM06061.1 - 1.5e-10 41.5 17.6 2.1e-10 41.1 12.2 1.2 1 0 0 1 1 1 1 4F5 protein family zf-met2 PF12907.2 KFM06061.1 - 2.6e-06 27.2 0.3 5e-06 26.3 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding zf-met PF12874.2 KFM06061.1 - 4e-05 23.6 0.2 6.4e-05 23.0 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFM06061.1 - 0.0067 16.5 0.1 0.012 15.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 KFM06061.1 - 0.022 14.9 1.4 0.045 13.9 1.0 1.6 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-Di19 PF05605.7 KFM06061.1 - 0.041 14.0 0.7 0.067 13.3 0.5 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-FCS PF06467.9 KFM06061.1 - 0.051 13.2 0.2 0.097 12.3 0.2 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif PRP21_like_P PF12230.3 KFM06061.1 - 0.14 11.6 4.3 0.17 11.3 3.0 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein zf-C2H2 PF00096.21 KFM06061.1 - 0.15 12.4 1.6 0.22 11.9 1.1 1.3 1 0 0 1 1 1 0 Zinc finger, C2H2 type Ribosomal_L44 PF00935.14 KFM06061.1 - 0.18 11.8 6.6 0.33 11.0 4.6 1.5 1 1 0 1 1 1 0 Ribosomal protein L44 AKAP95 PF04988.7 KFM06061.1 - 0.4 10.4 0.1 0.4 10.4 0.0 2.0 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Potyvirid-P3 PF13608.1 KFM06061.1 - 0.42 9.6 2.4 0.46 9.5 1.7 1.0 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein DUF3449 PF11931.3 KFM06061.1 - 6.3 6.2 8.2 1.3 8.5 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3449) 14-3-3 PF00244.15 KFM06062.1 - 1.1e-113 378.0 8.9 1.3e-113 377.9 6.1 1.0 1 0 0 1 1 1 1 14-3-3 protein CIA30 PF08547.7 KFM06062.1 - 0.05 13.4 0.0 0.082 12.7 0.0 1.3 1 0 0 1 1 1 0 Complex I intermediate-associated protein 30 (CIA30) FliM PF02154.10 KFM06062.1 - 0.063 12.9 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 Flagellar motor switch protein FliM CCDC-167 PF15188.1 KFM06062.1 - 1.1 9.2 4.7 0.76 9.7 0.3 2.5 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 DUF3461 PF11944.3 KFM06062.1 - 1.3 8.9 4.4 10 5.9 0.4 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3461) PX PF00787.19 KFM06063.1 - 3e-07 30.2 0.1 7.6e-07 28.9 0.0 1.8 1 0 0 1 1 1 1 PX domain FERM_N PF09379.5 KFM06063.1 - 0.0081 16.1 0.3 0.066 13.2 0.0 2.5 2 1 0 2 2 2 1 FERM N-terminal domain BTB_2 PF02214.17 KFM06064.1 - 2.9e-18 65.8 0.1 6.9e-18 64.6 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain SPRY PF00622.23 KFM06065.1 - 3.7e-12 46.4 0.0 4.7e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 SPRY domain IMS_HHH PF11798.3 KFM06065.1 - 0.15 12.1 0.0 0.55 10.3 0.0 1.9 2 0 0 2 2 2 0 IMS family HHH motif Arm PF00514.18 KFM06066.1 - 1.1e-84 275.7 16.9 3.2e-13 48.9 0.3 9.7 9 1 1 10 10 10 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFM06066.1 - 5.2e-23 81.1 0.1 6.5e-09 35.9 0.0 5.9 2 2 5 7 7 7 5 HEAT repeats HEAT PF02985.17 KFM06066.1 - 2e-18 64.7 7.9 0.0013 18.6 0.0 7.0 7 0 0 7 7 6 3 HEAT repeat HEAT_EZ PF13513.1 KFM06066.1 - 3e-18 65.7 1.7 2.5e-06 27.7 0.1 6.6 3 3 4 7 7 7 5 HEAT-like repeat Adaptin_N PF01602.15 KFM06066.1 - 5.7e-09 34.8 0.1 1.1e-08 33.8 0.1 1.4 1 1 0 1 1 1 1 Adaptin N terminal region IBB PF01749.15 KFM06066.1 - 3e-08 33.6 0.9 5.4e-08 32.9 0.6 1.4 1 0 0 1 1 1 1 Importin beta binding domain Arm_2 PF04826.8 KFM06066.1 - 9.7e-07 28.1 0.7 0.92 8.5 0.0 4.3 2 1 2 4 4 4 2 Armadillo-like V-ATPase_H_N PF03224.9 KFM06066.1 - 2.5e-05 23.5 0.5 0.0066 15.5 0.1 2.6 1 1 1 2 2 2 2 V-ATPase subunit H Proteasom_PSMB PF10508.4 KFM06066.1 - 9.9e-05 20.7 0.8 0.012 13.8 0.0 2.8 2 1 0 3 3 3 1 Proteasome non-ATPase 26S subunit V-ATPase_H_C PF11698.3 KFM06066.1 - 0.00039 20.3 0.5 6.5 6.7 0.0 4.2 4 1 1 5 5 5 1 V-ATPase subunit H DUF1981 PF09324.5 KFM06066.1 - 0.013 14.9 0.4 0.59 9.7 0.2 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF1981) Mo25 PF08569.6 KFM06066.1 - 0.023 13.7 0.1 0.063 12.2 0.0 1.8 1 0 0 1 1 1 0 Mo25-like Cnd3 PF12719.2 KFM06066.1 - 0.035 13.0 0.1 7.5 5.4 0.0 3.5 2 1 2 4 4 4 0 Nuclear condensing complex subunits, C-term domain RasGEF_N_2 PF14663.1 KFM06066.1 - 0.055 13.4 0.0 0.55 10.1 0.0 2.5 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Arf PF00025.16 KFM06067.1 - 7.1e-52 175.1 0.0 8.5e-52 174.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KFM06067.1 - 4.3e-09 35.9 0.0 5.8e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KFM06067.1 - 1.7e-08 33.8 0.0 2.2e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KFM06067.1 - 3.2e-08 32.6 0.0 2.8e-06 26.3 0.0 2.2 1 1 0 2 2 2 2 G-protein alpha subunit Miro PF08477.8 KFM06067.1 - 1.4e-07 32.0 0.0 1.8e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 KFM06067.1 - 6.4e-05 22.2 0.0 8.7e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFM06067.1 - 0.00023 21.1 0.0 0.00031 20.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RCC1 PF00415.13 KFM06068.1 - 4.3e-64 212.5 26.6 4.2e-16 58.8 1.5 6.3 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KFM06068.1 - 1.2e-32 110.7 31.7 2.8e-10 39.5 0.1 6.2 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 KFM06068.1 - 1.8e-22 79.4 0.6 1.9e-20 72.9 0.1 2.3 1 1 1 2 2 2 2 BTB/POZ domain BACK PF07707.10 KFM06068.1 - 6.8e-06 25.8 1.1 0.011 15.5 0.1 3.1 2 1 0 2 2 2 2 BTB And C-terminal Kelch SUKH-3 PF14433.1 KFM06068.1 - 0.058 13.1 0.6 2.3 7.9 0.0 3.3 3 0 0 3 3 3 0 SUKH-3 immunity protein PQQ_3 PF13570.1 KFM06068.1 - 1.1 9.5 4.3 12 6.2 0.0 3.7 4 0 0 4 4 4 0 PQQ-like domain SET PF00856.23 KFM06069.1 - 3.1e-33 115.3 1.4 2.8e-32 112.2 0.0 2.9 3 1 0 3 3 3 1 SET domain Pre-SET PF05033.11 KFM06069.1 - 1.2e-16 60.8 5.3 1.2e-16 60.8 3.7 3.0 3 0 0 3 3 3 1 Pre-SET motif MBD PF01429.14 KFM06069.1 - 4.9e-08 32.3 0.0 1.1e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Methyl-CpG binding domain Mo25 PF08569.6 KFM06070.1 - 4.6e-132 440.1 11.3 5.2e-132 439.9 7.8 1.0 1 0 0 1 1 1 1 Mo25-like HEAT_2 PF13646.1 KFM06070.1 - 0.0082 16.4 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 HEAT repeats UME PF08064.8 KFM06070.1 - 0.042 13.8 1.1 0.19 11.6 0.1 2.6 2 2 1 3 3 3 0 UME (NUC010) domain HEAT PF02985.17 KFM06070.1 - 0.11 12.5 0.0 19 5.6 0.0 2.8 2 0 0 2 2 2 0 HEAT repeat dCMP_cyt_deam_1 PF00383.17 KFM06071.1 - 3.1e-18 65.3 0.4 3.8e-09 36.1 0.0 2.6 2 1 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region PKD_channel PF08016.7 KFM06071.1 - 0.075 11.4 0.1 1.7 7.0 0.0 2.1 2 0 0 2 2 2 0 Polycystin cation channel DUF2772 PF10970.3 KFM06071.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2772) fn3 PF00041.16 KFM06072.1 - 4.1e-85 280.0 0.0 9e-11 41.7 0.0 9.8 9 1 0 9 9 9 9 Fibronectin type III domain SusE PF14292.1 KFM06072.1 - 4.7e-07 29.6 1.6 5 6.9 0.0 6.1 6 0 0 6 6 6 3 SusE outer membrane protein IL6Ra-bind PF09240.5 KFM06072.1 - 0.022 14.8 3.7 4 7.6 0.2 2.7 2 0 0 2 2 2 0 Interleukin-6 receptor alpha chain, binding DUF912 PF06024.7 KFM06072.1 - 0.049 13.6 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) 7tm_1 PF00001.16 KFM06073.1 - 1.6e-52 178.2 25.8 1.6e-52 178.2 17.9 1.3 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 KFM06073.1 - 1.2e-05 24.6 19.6 1.2e-05 24.6 13.6 2.2 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.1 KFM06073.1 - 0.00011 21.9 13.6 0.00011 21.9 9.4 2.8 1 1 1 2 2 2 1 Olfactory receptor 7TM_GPCR_Srw PF10324.4 KFM06073.1 - 0.00013 21.2 27.6 0.0045 16.1 19.2 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw TAS2R PF05296.8 KFM06073.1 - 0.015 14.2 26.9 0.11 11.3 18.7 1.9 1 1 0 1 1 1 0 Mammalian taste receptor protein (TAS2R) RCC1 PF00415.13 KFM06074.1 - 5.6e-64 212.1 24.8 7.4e-16 58.1 0.9 6.2 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KFM06074.1 - 1.8e-31 107.0 25.0 2.8e-11 42.6 0.8 5.8 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 KFM06074.1 - 2.2e-20 72.6 1.3 1.2e-17 63.8 0.1 2.3 1 1 1 2 2 2 2 BTB/POZ domain BACK PF07707.10 KFM06074.1 - 1.3e-05 25.0 2.4 0.00077 19.2 0.2 3.1 2 1 1 3 3 3 1 BTB And C-terminal Kelch DUF4213 PF13938.1 KFM06074.1 - 0.034 14.2 0.1 1.7 8.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4213) CBM_X PF06204.6 KFM06074.1 - 4.5 6.8 12.4 12 5.4 0.1 4.6 5 0 0 5 5 5 0 Putative carbohydrate binding domain Kelch_2 PF07646.10 KFM06074.1 - 4.7 7.1 8.5 13 5.7 0.1 4.7 5 0 0 5 5 5 0 Kelch motif TCTP PF00838.12 KFM06075.1 - 5.8e-57 192.2 0.1 6.6e-57 192.0 0.1 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein URO-D PF01208.12 KFM06075.1 - 0.09 11.6 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) Phage_int_SAM_4 PF13495.1 KFM06075.1 - 0.1 12.9 0.3 0.15 12.4 0.2 1.2 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain TFIIF_beta PF02270.10 KFM06076.1 - 9.2e-78 261.8 7.4 2e-76 257.3 5.1 2.0 1 1 0 1 1 1 1 Transcription initiation factor IIF, beta subunit Wound_ind PF08186.6 KFM06076.1 - 0.078 12.8 1.3 1.6 8.7 0.0 2.8 3 0 0 3 3 3 0 Wound-inducible basic protein family BTB_2 PF02214.17 KFM06077.1 - 7.5e-18 64.5 0.0 1.8e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain DUF3752 PF12572.3 KFM06078.1 - 1.6e-32 112.7 17.1 1.6e-32 112.7 11.8 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) NUFIP1 PF10453.4 KFM06079.1 - 3.1e-23 81.0 5.8 9.5e-23 79.4 4.0 1.9 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-C2H2_jaz PF12171.3 KFM06079.1 - 2.5e-05 24.2 4.0 0.00026 21.0 2.9 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 KFM06079.1 - 0.21 12.0 1.6 0.75 10.2 1.1 2.1 1 0 0 1 1 1 0 Zinc finger, C2H2 type Yae1_N PF09811.4 KFM06080.1 - 8.2e-11 41.2 27.0 0.11 12.0 18.7 3.1 1 1 0 1 1 1 1 Essential protein Yae1, N terminal TSC22 PF01166.13 KFM06082.1 - 2.3e-31 107.5 4.7 2.8e-31 107.2 3.2 1.1 1 0 0 1 1 1 1 TSC-22/dip/bun family DUF972 PF06156.8 KFM06082.1 - 0.00056 20.2 3.0 0.00065 20.0 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF972) MAD PF05557.8 KFM06082.1 - 0.00084 17.5 2.0 0.00091 17.4 1.4 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein DivIC PF04977.10 KFM06082.1 - 0.0029 17.0 4.8 0.0032 16.9 3.1 1.3 1 1 0 1 1 1 1 Septum formation initiator DUF904 PF06005.7 KFM06082.1 - 0.0097 16.1 8.7 0.016 15.4 6.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF904) Nnf1 PF03980.9 KFM06082.1 - 0.01 15.8 0.7 0.012 15.5 0.5 1.2 1 0 0 1 1 1 0 Nnf1 DUF16 PF01519.11 KFM06082.1 - 0.011 15.9 2.5 0.012 15.7 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF16 Lebercilin PF15619.1 KFM06082.1 - 0.012 15.0 2.5 0.015 14.7 1.7 1.1 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease bZIP_2 PF07716.10 KFM06082.1 - 0.023 14.5 5.0 0.038 13.8 3.5 1.3 1 0 0 1 1 1 0 Basic region leucine zipper DUF948 PF06103.6 KFM06082.1 - 0.031 14.1 0.9 0.037 13.8 0.6 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Fzo_mitofusin PF04799.8 KFM06082.1 - 0.057 12.8 1.6 0.062 12.6 1.1 1.0 1 0 0 1 1 1 0 fzo-like conserved region COG2 PF06148.6 KFM06082.1 - 0.073 12.9 1.6 0.097 12.5 1.1 1.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 NYD-SP28_assoc PF14775.1 KFM06082.1 - 0.08 12.6 1.5 0.12 12.0 1.1 1.3 1 0 0 1 1 1 0 Sperm tail C-terminal domain bZIP_1 PF00170.16 KFM06082.1 - 0.11 12.4 5.4 0.14 12.1 3.5 1.4 1 1 0 1 1 1 0 bZIP transcription factor Shugoshin_N PF07558.6 KFM06082.1 - 0.19 11.4 2.9 0.37 10.5 2.0 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Cu-oxidase_4 PF02578.10 KFM06083.1 - 1.7e-61 207.3 0.0 2.2e-61 206.9 0.0 1.1 1 0 0 1 1 1 1 Multi-copper polyphenol oxidoreductase laccase DUF904 PF06005.7 KFM06084.1 - 0.0063 16.7 8.4 0.0063 16.7 5.8 4.9 2 2 2 4 4 4 1 Protein of unknown function (DUF904) CENP-F_leu_zip PF10473.4 KFM06084.1 - 0.065 13.0 39.9 2.5 7.9 6.9 4.1 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HALZ PF02183.13 KFM06084.1 - 0.11 12.2 0.4 0.11 12.2 0.3 5.2 6 1 0 6 6 6 0 Homeobox associated leucine zipper DUF1619 PF07773.6 KFM06084.1 - 0.4 10.4 6.3 0.52 10.0 4.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1619) Baculo_PEP_C PF04513.7 KFM06084.1 - 0.55 10.0 6.4 0.48 10.2 0.5 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus LINES_C PF14695.1 KFM06084.1 - 1.1 8.5 3.5 75 2.6 0.0 3.9 4 0 0 4 4 4 0 Lines C-terminus FlxA PF14282.1 KFM06084.1 - 1.3 9.0 22.2 2.2 8.2 4.5 2.9 2 2 0 2 2 2 0 FlxA-like protein Fer4_12 PF13353.1 KFM06084.1 - 1.9 8.6 5.7 4.5 7.3 0.3 3.1 2 2 1 3 3 3 0 4Fe-4S single cluster domain IncA PF04156.9 KFM06084.1 - 2.4 7.7 38.4 4.2 6.9 7.4 3.1 1 1 2 3 3 3 0 IncA protein DUF464 PF04327.7 KFM06084.1 - 4.3 7.6 9.5 0.65 10.2 0.4 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF464) ADIP PF11559.3 KFM06084.1 - 6.3 6.6 36.3 2 8.2 8.4 3.1 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Laminin_EGF PF00053.19 KFM06085.1 - 5.2e-19 67.9 37.6 2.9e-11 43.1 10.1 2.7 3 0 0 3 3 3 2 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 KFM06085.1 - 0.034 14.3 7.2 0.034 14.3 5.0 4.6 4 2 1 5 5 5 0 EGF-like domain GCC2_GCC3 PF07699.8 KFM06085.1 - 2.2 7.9 25.2 14 5.3 8.7 3.5 1 1 1 2 2 2 0 GCC2 and GCC3 Yae1_N PF09811.4 KFM06086.1 - 1.7e-08 33.8 22.8 0.55 9.8 15.8 2.7 1 1 0 1 1 1 1 Essential protein Yae1, N terminal zf-H2C2_2 PF13465.1 KFM06089.1 - 9.8e-32 107.6 61.3 4e-08 33.1 0.7 11.6 12 0 0 12 12 12 7 Zinc-finger double domain zf-C2H2 PF00096.21 KFM06089.1 - 3.9e-31 105.5 74.7 0.00011 22.2 0.1 10.4 10 0 0 10 10 10 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM06089.1 - 1.1e-26 91.0 66.3 0.00011 22.2 0.4 10.1 10 0 0 10 10 10 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM06089.1 - 1.3e-21 76.1 45.1 0.0012 18.9 0.9 9.8 10 0 0 10 10 10 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM06089.1 - 2.9e-19 68.5 60.0 0.0023 18.0 0.3 9.8 10 0 0 10 10 10 8 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KFM06089.1 - 0.18 11.9 44.5 0.44 10.6 1.3 8.8 4 4 5 9 9 9 0 C2H2 type zinc-finger (2 copies) DUF2225 PF09986.4 KFM06089.1 - 0.35 10.3 0.0 0.35 10.3 0.0 2.6 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) BolA PF01722.13 KFM06089.1 - 0.4 10.6 4.2 33 4.5 0.1 4.0 4 0 0 4 4 4 0 BolA-like protein Elf1 PF05129.8 KFM06089.1 - 2.4 7.9 29.4 1.1 9.0 0.2 5.6 4 1 1 5 5 5 0 Transcription elongation factor Elf1 like E1-E2_ATPase PF00122.15 KFM06090.1 - 8.6e-25 87.1 0.0 1.7e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KFM06090.1 - 5.1e-16 59.7 0.0 1.2e-15 58.5 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFM06090.1 - 4.8e-14 52.9 0.0 3.9e-13 50.0 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFM06090.1 - 3.9e-05 23.5 0.0 0.00018 21.4 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFM06090.1 - 0.00037 20.1 0.0 0.001 18.6 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF443 PF04276.7 KFM06090.1 - 0.022 14.2 0.3 0.022 14.2 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF443) DUF4174 PF13778.1 KFM06090.1 - 0.071 13.2 0.2 0.2 11.7 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) RHD PF00554.17 KFM06091.1 - 1.4e-25 89.9 0.1 5.1e-25 88.1 0.0 2.0 1 1 0 1 1 1 1 Rel homology domain (RHD) TIG PF01833.19 KFM06091.1 - 1.2e-06 28.3 0.0 5.6e-06 26.2 0.0 2.3 1 0 0 1 1 1 1 IPT/TIG domain FCP1_C PF09309.5 KFM06092.1 - 2.8e-121 403.7 18.4 2.8e-121 403.7 12.8 3.0 2 1 0 2 2 2 1 FCP1, C-terminal NIF PF03031.13 KFM06092.1 - 1.7e-23 83.0 0.0 5.5e-23 81.3 0.0 1.9 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 KFM06092.1 - 2e-14 53.1 0.0 4.7e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 KFM06092.1 - 0.00019 21.4 0.4 0.00071 19.6 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BTB_2 PF02214.17 KFM06095.1 - 2.8e-28 97.9 0.0 5.7e-28 96.9 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans PF00520.26 KFM06095.1 - 3.3e-28 98.3 3.7 3.3e-28 98.3 2.6 1.7 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 KFM06095.1 - 3.3e-14 52.3 4.7 9.8e-14 50.8 1.6 2.4 2 0 0 2 2 2 1 Ion channel DUF979 PF06166.7 KFM06095.1 - 0.025 13.5 0.3 0.22 10.4 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF979) PQ-loop PF04193.9 KFM06096.1 - 1.9e-31 107.3 10.9 2.3e-19 68.6 0.1 3.8 3 1 1 4 4 4 2 PQ loop repeat MtN3_slv PF03083.11 KFM06096.1 - 0.0054 16.5 9.4 0.016 15.0 1.8 2.8 2 1 0 2 2 2 2 Sugar efflux transporter for intercellular exchange ER_lumen_recept PF00810.13 KFM06096.1 - 0.044 14.2 8.9 0.079 13.4 0.4 3.0 3 1 1 4 4 4 0 ER lumen protein retaining receptor DUF2678 PF10856.3 KFM06096.1 - 0.11 12.2 2.4 0.098 12.3 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) HSBP1 PF06825.7 KFM06097.1 - 2.7e-11 42.8 2.5 6.3e-11 41.6 1.7 1.6 1 1 0 1 1 1 1 Heat shock factor binding protein 1 DUF1974 PF09317.6 KFM06097.1 - 0.012 15.0 0.0 0.013 14.9 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) YvrJ PF12841.2 KFM06097.1 - 0.026 13.8 1.4 4.2 6.7 0.2 2.1 2 0 0 2 2 2 0 YvrJ protein family UCH_1 PF13423.1 KFM06097.1 - 0.11 11.8 0.3 0.11 11.8 0.2 1.0 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase GvpK PF05121.7 KFM06097.1 - 0.12 12.1 2.2 0.28 11.0 0.2 1.9 1 1 1 2 2 2 0 Gas vesicle protein K Erythro-docking PF09277.6 KFM06097.1 - 0.15 11.7 0.3 0.26 11.0 0.2 1.4 1 0 0 1 1 1 0 Erythronolide synthase, docking MazG PF03819.12 KFM06097.1 - 0.29 11.1 1.6 2.3 8.2 0.4 2.0 1 1 1 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain DIM1 PF02966.11 KFM06098.1 - 4.5e-71 236.5 0.3 5.1e-71 236.4 0.2 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 KFM06098.1 - 7.8e-06 25.5 0.1 1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 KFM06098.1 - 0.0066 16.4 0.1 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.1 KFM06098.1 - 0.012 15.7 0.3 0.019 15.0 0.2 1.3 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_2 PF13098.1 KFM06098.1 - 0.082 13.1 0.1 0.11 12.6 0.1 1.3 1 1 0 1 1 1 0 Thioredoxin-like domain 2-Hacid_dh_C PF02826.14 KFM06099.1 - 1.1e-59 200.5 0.0 1.6e-59 200.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFM06099.1 - 2.5e-20 72.3 0.0 2.8e-20 72.1 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KFM06099.1 - 5.4e-11 42.5 0.6 1.7e-10 40.9 0.1 2.0 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.17 KFM06099.1 - 0.00055 20.4 0.0 0.0015 19.0 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 KFM06099.1 - 0.00067 20.0 0.1 0.002 18.4 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_N PF05222.10 KFM06099.1 - 0.0016 18.4 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain IlvN PF07991.7 KFM06099.1 - 0.0034 16.7 0.0 0.005 16.2 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain AdoHcyase_NAD PF00670.16 KFM06099.1 - 0.0084 15.9 0.0 2.5 7.9 0.0 2.4 2 0 0 2 2 2 2 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TrkA_N PF02254.13 KFM06099.1 - 0.01 15.8 0.2 0.15 12.0 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain AlaDh_PNT_C PF01262.16 KFM06099.1 - 0.035 13.6 0.1 0.37 10.3 0.0 2.2 2 1 1 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 KFM06100.1 - 3.6e-61 205.4 0.0 5e-61 204.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFM06100.1 - 3.2e-17 62.2 0.0 3.6e-17 62.0 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KFM06100.1 - 1.1e-09 38.2 0.1 1.9e-09 37.5 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 KFM06100.1 - 0.019 14.8 0.0 7.6 6.3 0.0 2.2 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain GFO_IDH_MocA PF01408.17 KFM06100.1 - 0.022 15.2 0.0 0.037 14.5 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold TrkA_N PF02254.13 KFM06100.1 - 0.023 14.6 0.3 0.3 11.0 0.0 2.4 3 0 0 3 3 3 0 TrkA-N domain AlaDh_PNT_C PF01262.16 KFM06100.1 - 0.024 14.1 0.2 0.24 10.9 0.2 2.1 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.7 KFM06100.1 - 0.063 12.6 0.1 0.087 12.1 0.1 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 KFM06100.1 - 0.12 12.7 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent RBFA PF02033.13 KFM06101.1 - 2e-07 30.9 0.1 5e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Ribosome-binding factor A HTH_OrfB_IS605 PF12323.3 KFM06101.1 - 0.13 11.5 0.4 5.9 6.2 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain PRP21_like_P PF12230.3 KFM06102.1 - 0.0019 17.7 0.7 0.57 9.6 0.1 2.7 2 0 0 2 2 2 2 Pre-mRNA splicing factor PRP21 like protein Homeobox PF00046.24 KFM06102.1 - 0.011 15.3 0.1 0.03 13.9 0.0 1.7 1 0 0 1 1 1 0 Homeobox domain DUF2719 PF10891.3 KFM06102.1 - 0.49 10.1 7.3 0.62 9.7 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2719) zf-C2H2_6 PF13912.1 KFM06102.1 - 2.1 8.3 22.5 1.6 8.7 0.2 5.5 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KFM06102.1 - 3.6 8.1 47.1 0.54 10.7 0.2 8.4 8 0 0 8 8 8 0 C2H2-type zinc finger CUB PF00431.15 KFM06103.1 - 8.7e-281 910.9 0.0 1.5e-25 89.3 0.0 12.4 12 0 0 12 12 12 12 CUB domain Sushi PF00084.15 KFM06103.1 - 6e-243 785.4 176.3 5.1e-11 42.7 0.4 27.6 27 0 0 27 27 27 27 Sushi domain (SCR repeat) CUB_2 PF02408.15 KFM06103.1 - 1.2e-24 86.1 12.9 0.012 15.0 0.2 11.4 11 0 0 11 11 11 8 CUB-like domain PHZA_PHZB PF03284.8 KFM06103.1 - 0.3 10.1 3.6 1.8e+02 1.1 0.0 5.5 7 0 0 7 7 7 0 Phenazine biosynthesis protein A/B CD34_antigen PF06365.7 KFM06103.1 - 2.8 7.5 0.0 4.8 6.7 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family GATA PF00320.22 KFM06105.1 - 1.2e-12 46.9 5.1 1.2e-12 46.9 3.5 2.6 2 0 0 2 2 2 1 GATA zinc finger zf-H2C2_5 PF13909.1 KFM06105.1 - 2e-07 30.8 73.6 0.00048 20.1 1.6 9.1 9 0 0 9 9 9 6 C2H2-type zinc-finger domain JAB PF01398.16 KFM06108.1 - 8.2e-18 64.2 0.3 8.2e-18 64.2 0.2 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RasGAP_C PF03836.10 KFM06108.1 - 0.22 11.1 10.8 0.15 11.7 4.8 2.3 2 1 0 2 2 2 0 RasGAP C-terminus Fcf1 PF04900.7 KFM06109.1 - 3.9e-25 87.8 2.4 1.1e-24 86.3 0.0 2.3 2 1 1 3 3 3 1 Fcf1 Nucleo_P87 PF07267.6 KFM06109.1 - 0.058 12.0 2.9 0.055 12.1 2.0 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 TATR PF03430.8 KFM06109.1 - 0.7 8.4 6.3 0.78 8.3 4.4 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Rad21_Rec8_N PF04825.8 KFM06110.1 - 1.4e-43 147.3 0.0 2.7e-43 146.4 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 KFM06110.1 - 8.3e-23 79.3 0.2 3.3e-22 77.4 0.1 2.1 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 KFM06110.1 - 3.1e-08 33.4 1.8 6.3e-08 32.5 0.4 2.1 2 0 0 2 2 2 1 ScpA/B protein V-ATPase_G PF03179.10 KFM06110.1 - 0.28 11.4 7.8 0.06 13.6 2.7 1.9 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Cation_efflux PF01545.16 KFM06111.1 - 1.8e-56 191.3 14.7 2.3e-56 190.9 10.2 1.0 1 0 0 1 1 1 1 Cation efflux family DUF1198 PF06711.6 KFM06111.1 - 0.073 12.8 0.5 0.25 11.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1198) Med30 PF11315.3 KFM06112.1 - 4.6e-66 221.5 1.5 5.2e-66 221.4 1.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 30 UPF0449 PF15136.1 KFM06112.1 - 0.094 12.9 4.0 0.13 12.5 1.2 2.1 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 AKNA PF12443.3 KFM06112.1 - 0.1 12.5 0.9 0.5 10.4 0.2 2.1 2 0 0 2 2 2 0 AT-hook-containing transcription factor NYD-SP28_assoc PF14775.1 KFM06112.1 - 0.65 9.7 5.4 1.4 8.7 3.7 1.5 1 0 0 1 1 1 0 Sperm tail C-terminal domain Glyco_transf_64 PF09258.5 KFM06113.1 - 1.2e-105 352.0 0.7 1.8e-105 351.5 0.5 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Exostosin PF03016.10 KFM06113.1 - 3.6e-26 91.8 0.0 8.7e-26 90.6 0.0 1.7 1 0 0 1 1 1 1 Exostosin family KicB PF03882.9 KFM06113.1 - 0.026 13.1 0.2 0.038 12.6 0.1 1.1 1 0 0 1 1 1 0 KicB killing factor Ribosom_S12_S23 PF00164.20 KFM06114.1 - 1.6e-05 24.2 0.1 1.6e-05 24.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 SAM_2 PF07647.12 KFM06115.1 - 8e-18 64.0 1.0 1.1e-17 63.6 0.7 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFM06115.1 - 1.8e-11 44.0 0.9 2.7e-11 43.4 0.6 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 KFM06115.1 - 8.3e-09 35.0 0.1 1.2e-08 34.6 0.1 1.2 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain HTH_32 PF13565.1 KFM06115.1 - 0.069 13.9 0.8 0.13 13.0 0.2 1.7 1 1 1 2 2 2 0 Homeodomain-like domain Death PF00531.17 KFM06116.1 - 4.2e-20 71.3 1.0 3.9e-11 42.5 0.0 2.4 2 0 0 2 2 2 2 Death domain TNFR_c6 PF00020.13 KFM06116.1 - 5.3e-14 51.9 32.0 7.7e-06 25.8 7.4 4.6 4 0 0 4 4 4 3 TNFR/NGFR cysteine-rich region GCC2_GCC3 PF07699.8 KFM06116.1 - 0.012 15.1 1.7 0.012 15.1 1.2 4.0 1 1 3 4 4 4 0 GCC2 and GCC3 tRNA_NucTran2_2 PF13735.1 KFM06116.1 - 0.072 12.9 2.6 1.1 9.1 0.1 2.7 2 1 0 2 2 2 0 tRNA nucleotidyltransferase domain 2 putative Lectin_C PF00059.16 KFM06117.1 - 4.6e-17 62.5 0.1 6.8e-17 62.0 0.1 1.3 1 0 0 1 1 1 1 Lectin C-type domain Collagen PF01391.13 KFM06117.1 - 4.3e-12 45.3 52.5 2e-07 30.4 16.1 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) MARVEL PF01284.18 KFM06118.1 - 1.3e-10 41.2 9.1 1.4e-10 41.1 6.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF4131 PF13567.1 KFM06118.1 - 0.014 14.8 4.9 0.013 14.9 2.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) 2-oxoacid_dh PF00198.18 KFM06118.1 - 0.079 12.2 0.0 0.097 11.9 0.0 1.1 1 0 0 1 1 1 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Peptidase_U4 PF03419.8 KFM06118.1 - 3.5 6.6 6.8 6.6 5.7 4.7 1.5 1 1 0 1 1 1 0 Sporulation factor SpoIIGA DUF4227 PF14004.1 KFM06118.1 - 4 7.3 7.8 0.21 11.4 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4227) DUF3687 PF12459.3 KFM06118.1 - 4.7 6.5 10.3 0.25 10.5 2.1 2.2 1 1 1 2 2 2 0 D-Ala-teichoic acid biosynthesis protein Cys_knot PF00007.17 KFM06119.1 - 2.7e-15 56.3 14.8 2.7e-15 56.3 10.2 2.8 3 0 0 3 3 3 1 Cystine-knot domain VWC PF00093.13 KFM06119.1 - 5.7e-12 45.5 8.9 5.7e-12 45.5 6.2 4.3 2 1 1 3 3 3 1 von Willebrand factor type C domain TSP_1 PF00090.14 KFM06119.1 - 1.6e-09 37.7 9.7 1.6e-09 37.7 6.7 2.6 3 0 0 3 3 3 1 Thrombospondin type 1 domain Phosphodiest PF01663.17 KFM06121.1 - 1.2e-74 251.8 0.1 1.8e-38 132.7 0.2 2.3 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Somatomedin_B PF01033.12 KFM06121.1 - 1.5e-19 69.6 43.9 2.5e-10 40.1 9.5 3.2 3 0 0 3 3 3 2 Somatomedin B domain Endonuclease_NS PF01223.18 KFM06121.1 - 1.9e-13 50.5 0.0 4.3e-13 49.3 0.0 1.6 2 0 0 2 2 2 1 DNA/RNA non-specific endonuclease Sulfatase PF00884.18 KFM06121.1 - 3.9e-05 22.9 0.0 0.012 14.8 0.0 2.2 2 0 0 2 2 2 2 Sulfatase Peptidase_M1 PF01433.15 KFM06122.1 - 1.7e-13 50.4 1.0 4.8e-13 48.9 0.7 1.7 1 1 0 1 1 1 1 Peptidase family M1 HEAT_2 PF13646.1 KFM06122.1 - 0.0033 17.6 0.1 0.1 12.8 0.0 3.2 3 1 0 3 3 3 1 HEAT repeats HEAT PF02985.17 KFM06122.1 - 0.92 9.7 5.7 8.4 6.7 0.1 4.5 5 0 0 5 5 5 0 HEAT repeat DUF2036 PF09724.4 KFM06123.1 - 7.6e-95 317.7 3.2 8.8e-95 317.5 2.2 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) DEP PF00610.16 KFM06124.1 - 1.8e-44 149.3 1.9 8.4e-24 83.1 0.2 2.3 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PDZ_2 PF13180.1 KFM06124.1 - 0.03 14.1 0.0 0.066 13.0 0.0 1.5 1 0 0 1 1 1 0 PDZ domain DUF3658 PF12395.3 KFM06124.1 - 0.068 12.7 0.2 3.8 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function PDZ PF00595.19 KFM06124.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) VWA PF00092.23 KFM06125.1 - 7.5e-104 345.0 1.0 3.3e-51 173.5 0.0 2.7 3 0 0 3 3 3 2 von Willebrand factor type A domain fn3 PF00041.16 KFM06125.1 - 2.3e-96 316.0 8.3 1.5e-13 50.6 0.0 8.3 8 0 0 8 8 8 8 Fibronectin type III domain Collagen PF01391.13 KFM06125.1 - 2.4e-37 126.2 166.7 1.8e-08 33.7 21.9 5.5 2 2 3 5 5 5 5 Collagen triple helix repeat (20 copies) VWA_2 PF13519.1 KFM06125.1 - 1.7e-23 83.5 0.0 1.6e-11 44.5 0.0 2.6 2 0 0 2 2 2 2 von Willebrand factor type A domain Laminin_G_3 PF13385.1 KFM06125.1 - 0.0076 16.4 0.0 0.022 15.0 0.0 1.7 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily SusE PF14292.1 KFM06125.1 - 0.14 11.9 3.8 27 4.5 0.0 4.3 5 0 0 5 5 5 0 SusE outer membrane protein Ribosomal_L13 PF00572.13 KFM06126.1 - 1.3e-06 28.4 0.1 1.7e-06 28.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 MTBP_mid PF14919.1 KFM06127.1 - 3.9e-162 538.7 0.5 6.1e-162 538.0 0.4 1.3 1 0 0 1 1 1 1 MDM2-binding MTBP_C PF14920.1 KFM06127.1 - 3.6e-126 419.8 8.3 5.8e-126 419.1 5.8 1.4 1 0 0 1 1 1 1 MDM2-binding MTBP_N PF14918.1 KFM06127.1 - 2.9e-113 377.8 2.5 6.6e-113 376.6 1.7 1.6 1 0 0 1 1 1 1 MDM2-binding PH PF00169.24 KFM06128.1 - 1.5e-09 38.0 0.0 2.1e-06 27.9 0.0 2.3 2 0 0 2 2 2 2 PH domain DER1 PF04511.10 KFM06129.1 - 1.5e-49 168.1 8.8 1.8e-49 167.9 6.1 1.0 1 0 0 1 1 1 1 Der1-like family DUF3341 PF11821.3 KFM06129.1 - 0.12 11.8 0.1 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) RabGAP-TBC PF00566.13 KFM06130.1 - 3.1e-10 39.8 4.3 1.3e-09 37.8 3.0 2.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain WD40 PF00400.27 KFM06130.1 - 3.5e-09 36.2 7.2 0.0048 16.7 0.4 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat PQQ_3 PF13570.1 KFM06130.1 - 0.0079 16.4 0.0 2.7 8.3 0.0 2.6 2 0 0 2 2 2 1 PQQ-like domain Nbas_N PF15492.1 KFM06130.1 - 0.03 13.4 0.0 0.1 11.6 0.0 1.8 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Neisseria_PilC PF05567.6 KFM06130.1 - 0.15 11.1 0.0 0.28 10.1 0.0 1.4 1 0 0 1 1 1 0 Neisseria PilC beta-propeller domain DUF1669 PF07894.7 KFM06131.1 - 8.4e-101 336.9 0.1 1.1e-100 336.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1669) PLDc_2 PF13091.1 KFM06131.1 - 0.0058 16.3 0.1 0.024 14.3 0.0 2.0 2 0 0 2 2 2 1 PLD-like domain Atx10homo_assoc PF09759.4 KFM06131.1 - 0.11 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain TPR_16 PF13432.1 KFM06132.1 - 0.0057 17.2 0.4 2.4 8.9 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFM06132.1 - 0.011 16.3 0.0 6.6 7.6 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 KFM06132.1 - 0.013 15.1 0.8 3 7.5 0.1 2.5 2 0 0 2 2 2 0 TPR repeat TPR_19 PF14559.1 KFM06132.1 - 0.022 15.0 0.6 19 5.7 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFM06132.1 - 0.11 12.3 0.1 34 4.5 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 KFM06132.1 - 0.16 12.1 0.7 8.3 6.6 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 KFM06132.1 - 0.32 11.5 1.3 0.46 11.0 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Homeobox PF00046.24 KFM06133.1 - 2.7e-29 100.5 8.9 5.6e-08 32.2 0.0 4.4 4 0 0 4 4 4 4 Homeobox domain Homez PF11569.3 KFM06133.1 - 7.5e-29 98.5 3.1 7e-22 76.2 0.2 4.2 4 0 0 4 4 4 3 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.6 KFM06133.1 - 3.1e-18 65.1 1.1 8.1e-05 22.2 0.0 4.7 4 0 0 4 4 4 4 Homeobox KN domain zf-C2H2 PF00096.21 KFM06133.1 - 0.35 11.3 7.1 3 8.3 0.7 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM06133.1 - 1 9.8 5.2 7.2 7.1 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Nt_Gln_amidase PF09764.4 KFM06134.1 - 5.1e-66 221.4 0.0 5.8e-66 221.3 0.0 1.0 1 0 0 1 1 1 1 N-terminal glutamine amidase F-box-like PF12937.2 KFM06135.1 - 0.0072 16.0 3.1 0.0076 15.9 0.1 2.6 3 0 0 3 3 3 1 F-box-like Elongin_A PF06881.6 KFM06135.1 - 0.031 14.6 0.1 0.1 13.0 0.1 1.8 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box PF00646.28 KFM06135.1 - 0.074 12.7 0.1 0.074 12.7 0.1 2.8 3 0 0 3 3 3 0 F-box domain DUF4047 PF13256.1 KFM06135.1 - 0.095 12.6 1.6 0.21 11.5 0.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) Kelch_1 PF01344.20 KFM06136.1 - 7.4e-50 166.2 0.9 1.5e-11 43.6 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 KFM06136.1 - 6.3e-34 114.7 0.7 2.8e-06 27.2 0.0 6.4 2 2 4 6 6 6 6 Kelch motif Kelch_3 PF13415.1 KFM06136.1 - 1.1e-26 92.3 0.0 0.0016 18.5 0.0 6.4 5 1 1 6 6 6 6 Galactose oxidase, central domain BTB PF00651.26 KFM06136.1 - 4.9e-26 90.8 1.2 6.5e-26 90.4 0.1 1.8 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.10 KFM06136.1 - 1.3e-24 85.9 0.4 1.3e-24 85.9 0.3 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_4 PF13418.1 KFM06136.1 - 1.3e-24 85.6 0.1 0.00015 21.4 0.1 6.9 5 2 1 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.10 KFM06136.1 - 3.3e-22 77.3 0.2 0.00036 20.1 0.0 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.1 KFM06136.1 - 2.5e-19 68.7 3.0 0.00034 20.5 0.1 6.5 6 0 0 6 6 6 5 Kelch motif DUF3342 PF11822.3 KFM06136.1 - 0.0056 15.8 1.8 0.0057 15.8 0.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) DUF1668 PF07893.8 KFM06136.1 - 0.014 14.5 0.1 1.7 7.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1668) Annexin PF00191.15 KFM06137.1 - 8.6e-98 320.2 11.7 4.4e-26 90.5 0.0 4.1 4 0 0 4 4 4 4 Annexin Acetyltransf_11 PF13720.1 KFM06137.1 - 0.002 18.2 1.2 4.2 7.6 0.0 3.6 4 0 0 4 4 4 2 Udp N-acetylglucosamine O-acyltransferase; Domain 2 TSLP PF15216.1 KFM06137.1 - 0.0093 15.6 0.7 0.56 9.9 0.0 3.3 4 1 0 4 4 4 1 Thymic stromal lymphopoietin C2 PF00168.25 KFM06138.1 - 8.4e-68 224.2 0.7 3.6e-14 52.3 0.0 7.4 6 1 0 6 6 6 6 C2 domain FerB PF08150.7 KFM06138.1 - 1.6e-31 108.2 0.1 4.1e-31 106.8 0.1 1.8 1 0 0 1 1 1 1 FerB (NUC096) domain FerI PF08151.7 KFM06138.1 - 5.3e-28 96.8 0.0 1.3e-27 95.5 0.0 1.8 1 0 0 1 1 1 1 FerI (NUC094) domain Synaptobrevin PF00957.16 KFM06138.1 - 1.8 8.1 6.7 4.1 7.0 4.7 1.5 1 0 0 1 1 1 0 Synaptobrevin DUF2453 PF10507.4 KFM06139.1 - 9.1e-46 154.2 3.4 1.1e-45 154.0 2.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2453) Romo1 PF10247.4 KFM06139.1 - 0.11 12.6 1.2 0.51 10.5 0.0 2.2 2 1 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 DUF2273 PF10031.4 KFM06139.1 - 0.13 11.8 0.3 0.13 11.8 0.2 2.6 2 1 0 2 2 2 0 Small integral membrane protein (DUF2273) DUF3789 PF12664.2 KFM06139.1 - 1.1 8.6 3.3 0.42 9.9 0.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3789) TRC8_N PF13705.1 KFM06140.1 - 2.3e-170 567.5 41.5 2.6e-170 567.3 28.8 1.0 1 0 0 1 1 1 1 TRC8 N-terminal domain zf-RING_2 PF13639.1 KFM06140.1 - 3.8e-11 42.6 9.2 3.8e-11 42.6 6.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 KFM06140.1 - 2.6e-08 33.8 6.4 2.6e-08 33.8 4.5 2.1 2 1 0 2 2 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KFM06140.1 - 7.6e-07 29.0 7.9 7.6e-07 29.0 5.5 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM06140.1 - 1.4e-06 27.8 8.0 1.4e-06 27.8 5.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM06140.1 - 4.3e-06 26.3 4.7 4.3e-06 26.3 3.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM06140.1 - 1.3e-05 24.8 7.5 1.3e-05 24.8 5.2 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 KFM06140.1 - 7.2e-05 22.5 5.8 0.00094 18.9 4.0 2.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 KFM06140.1 - 0.075 13.0 8.4 1.8 8.6 5.9 2.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H PF13771.1 KFM06140.1 - 0.12 12.4 2.9 0.35 11.0 2.0 1.8 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-P11 PF03854.9 KFM06140.1 - 0.53 9.8 5.3 2.1 7.8 3.7 2.1 1 0 0 1 1 1 0 P-11 zinc finger TatD_DNase PF01026.16 KFM06141.1 - 5.5e-52 176.5 0.0 6.6e-52 176.2 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Complex1_LYR PF05347.10 KFM06142.1 - 1.5e-12 47.0 0.9 3.3e-12 46.0 0.6 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KFM06142.1 - 3e-08 33.7 0.7 5.4e-08 32.9 0.5 1.4 1 0 0 1 1 1 1 Complex1_LYR-like IMD PF08397.6 KFM06143.1 - 4.2e-69 232.2 4.7 5.6e-69 231.7 3.2 1.2 1 0 0 1 1 1 1 IRSp53/MIM homology domain Gp58 PF07902.6 KFM06143.1 - 0.078 11.1 0.4 0.11 10.7 0.3 1.1 1 0 0 1 1 1 0 gp58-like protein SE PF08491.5 KFM06144.1 - 3.3e-110 367.2 0.0 4.2e-110 366.9 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 KFM06144.1 - 1.9e-20 73.2 0.0 2.8e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFM06144.1 - 2.3e-13 49.8 0.0 8.2e-06 24.9 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFM06144.1 - 9.1e-05 22.7 0.1 0.0002 21.7 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFM06144.1 - 0.00018 20.4 0.2 0.33 9.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KFM06144.1 - 0.0013 18.7 0.1 0.0027 17.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 KFM06144.1 - 0.0035 17.3 0.1 0.0073 16.2 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.13 KFM06144.1 - 0.0042 16.7 0.0 0.0072 15.9 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GMC_oxred_N PF00732.14 KFM06144.1 - 0.0067 15.6 0.0 2.9 6.9 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase Thi4 PF01946.12 KFM06144.1 - 0.0075 15.3 0.0 0.031 13.3 0.0 1.8 2 0 0 2 2 2 1 Thi4 family ApbA PF02558.11 KFM06144.1 - 0.016 14.6 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 KFM06144.1 - 0.018 14.7 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_2 PF07992.9 KFM06144.1 - 0.027 14.3 0.0 0.052 13.4 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KFM06144.1 - 0.028 13.0 0.1 2.2 6.7 0.1 2.6 2 1 1 3 3 3 0 Tryptophan halogenase Saccharop_dh PF03435.13 KFM06144.1 - 0.028 13.4 0.1 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_2 PF03446.10 KFM06144.1 - 0.055 13.3 0.0 0.099 12.4 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 KFM06144.1 - 0.061 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.9 KFM06144.1 - 0.088 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Strumpellin PF10266.4 KFM06145.1 - 0 1579.1 23.5 0 1578.9 16.3 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin EF-hand_9 PF14658.1 KFM06145.1 - 0.069 13.0 0.1 0.46 10.4 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain UPF0149 PF03695.8 KFM06145.1 - 0.15 11.9 0.3 1.6 8.6 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0149) zf-Nse PF11789.3 KFM06146.1 - 7.6e-21 73.3 2.6 1.4e-20 72.5 1.8 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 KFM06146.1 - 4.7e-09 35.8 1.1 1.2e-08 34.5 0.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 KFM06146.1 - 0.00018 20.8 1.7 0.00018 20.8 1.2 2.0 1 1 1 2 2 2 1 Rtf2 RING-finger zf-MIZ PF02891.15 KFM06146.1 - 0.00048 19.5 1.6 0.0012 18.2 1.1 1.8 1 1 0 1 1 1 1 MIZ/SP-RING zinc finger U-box PF04564.10 KFM06146.1 - 0.0011 18.8 0.1 0.0034 17.3 0.0 1.9 1 1 0 1 1 1 1 U-box domain zf-RING_2 PF13639.1 KFM06146.1 - 0.008 15.9 0.2 0.008 15.9 0.1 1.8 2 0 0 2 2 2 1 Ring finger domain Mnd1 PF03962.10 KFM06146.1 - 0.013 15.1 4.3 0.031 13.9 2.9 1.6 1 1 0 1 1 1 0 Mnd1 family FadA PF09403.5 KFM06146.1 - 0.094 12.7 5.5 0.16 11.9 3.8 1.3 1 0 0 1 1 1 0 Adhesion protein FadA zf-rbx1 PF12678.2 KFM06146.1 - 0.19 11.8 1.5 0.4 10.8 1.0 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger HalX PF08663.5 KFM06146.1 - 0.29 11.1 5.7 0.069 13.1 1.2 2.0 2 1 0 2 2 2 0 HalX domain zf-C3HC4 PF00097.20 KFM06146.1 - 0.53 9.9 3.5 0.25 11.0 0.3 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.20 KFM06147.1 - 7.6e-05 21.9 0.0 9.4e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain LRAT PF04970.8 KFM06148.1 - 1.1e-13 51.2 0.3 9.7e-12 44.9 0.2 2.3 1 1 0 1 1 1 1 Lecithin retinol acyltransferase NLPC_P60 PF00877.14 KFM06148.1 - 0.063 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 NlpC/P60 family DUF3049 PF11250.3 KFM06149.1 - 0.23 11.2 0.9 1.9 8.3 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3049) zf-CCCH PF00642.19 KFM06150.1 - 0.00051 19.6 3.3 0.00088 18.8 2.3 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KFM06150.1 - 0.49 10.4 4.2 0.77 9.8 2.9 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type CIDE-N PF02017.10 KFM06151.1 - 7.4e-13 48.0 0.0 1.2e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 CIDE-N domain zf-C2H2 PF00096.21 KFM06152.1 - 3.5e-07 30.1 23.3 0.0043 17.3 2.1 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM06152.1 - 2e-06 27.7 22.9 0.0015 18.6 0.5 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KFM06152.1 - 0.0016 18.5 11.1 0.0016 18.5 7.7 2.3 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KFM06152.1 - 0.02 15.0 0.9 0.02 15.0 0.6 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 KFM06152.1 - 0.063 13.5 21.8 0.11 12.8 1.6 3.8 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-FCS PF06467.9 KFM06152.1 - 0.65 9.6 6.8 2.1 8.0 0.1 3.2 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif DZR PF12773.2 KFM06152.1 - 6.7 6.6 8.0 6 6.7 1.1 2.5 2 0 0 2 2 2 0 Double zinc ribbon BEN PF10523.4 KFM06153.1 - 2.7e-10 40.1 0.1 6.2e-10 39.0 0.1 1.7 1 0 0 1 1 1 1 BEN domain Tbf5 PF06331.7 KFM06153.1 - 0.019 14.7 0.5 0.049 13.4 0.3 1.6 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 Carb_anhydrase PF00194.16 KFM06154.1 - 3e-107 357.3 0.0 3.7e-107 357.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase AA_permease_2 PF13520.1 KFM06155.1 - 1.6e-64 218.0 42.7 1.8e-64 217.8 29.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFM06155.1 - 7e-27 93.9 38.1 9.7e-27 93.4 26.4 1.1 1 0 0 1 1 1 1 Amino acid permease Kelch_3 PF13415.1 KFM06156.1 - 6.5e-43 143.9 0.5 4.2e-10 39.4 0.0 7.3 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_4 PF13418.1 KFM06156.1 - 7.2e-38 128.1 5.5 1.8e-09 37.2 0.0 6.9 6 3 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.1 KFM06156.1 - 2.4e-28 97.0 2.8 1.9e-06 27.8 0.0 6.1 5 1 1 6 6 6 5 Kelch motif Kelch_5 PF13854.1 KFM06156.1 - 1.3e-24 85.6 7.2 3.1e-06 27.0 0.1 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 KFM06156.1 - 1.4e-23 81.6 5.8 2.4e-05 23.8 0.0 7.4 6 3 0 6 6 6 5 Kelch motif Kelch_1 PF01344.20 KFM06156.1 - 6.9e-16 57.5 9.6 1.1e-05 24.8 0.0 6.8 6 1 0 6 6 6 4 Kelch motif DUF4110 PF13422.1 KFM06156.1 - 7e-06 25.7 0.2 7e-06 25.7 0.2 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF4110) Nop14 PF04147.7 KFM06156.1 - 1 7.2 15.2 1.4 6.7 10.5 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KFM06156.1 - 2.6 5.9 7.1 4.4 5.2 4.9 1.3 1 0 0 1 1 1 0 CDC45-like protein MORN PF02493.15 KFM06157.1 - 1.2e-41 137.9 67.5 7.9e-10 37.8 0.6 8.6 8 0 0 8 8 8 8 MORN repeat MTBP_C PF14920.1 KFM06157.1 - 0.045 13.2 3.4 0.077 12.4 2.4 1.3 1 0 0 1 1 1 0 MDM2-binding SAM_1 PF00536.25 KFM06158.1 - 1.1e-05 25.4 0.6 2.3e-05 24.4 0.4 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-CCHC PF00098.18 KFM06158.1 - 3.5e-05 23.5 1.8 3.5e-05 23.5 1.3 2.2 2 0 0 2 2 2 1 Zinc knuckle SAM_2 PF07647.12 KFM06158.1 - 0.0015 18.3 0.3 0.003 17.3 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Atg8 PF02991.11 KFM06159.1 - 8.5e-44 147.7 0.2 9.5e-44 147.6 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 KFM06159.1 - 1.5e-06 28.3 0.0 1.8e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 DUF2407 PF10302.4 KFM06159.1 - 0.032 14.4 0.0 0.049 13.8 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Telomere_Sde2 PF13019.1 KFM06159.1 - 0.065 12.9 0.0 0.071 12.8 0.0 1.1 1 0 0 1 1 1 0 Telomere stability and silencing DUF3506 PF12014.3 KFM06160.1 - 9.8e-06 25.4 1.0 0.072 12.8 0.0 3.4 2 1 1 4 4 4 2 Domain of unknown function (DUF3506) SBF2 PF12335.3 KFM06161.1 - 5.7e-05 22.5 2.9 0.00011 21.6 0.2 2.2 2 1 0 2 2 2 1 Myotubularin protein Sld5 PF05916.6 KFM06162.1 - 2.2e-11 43.9 0.9 2.4e-11 43.8 0.6 1.0 1 0 0 1 1 1 1 GINS complex protein UPF0172 PF03665.8 KFM06163.1 - 3.8e-43 147.2 0.9 4.2e-43 147.1 0.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) COX4 PF02936.9 KFM06164.1 - 1.2e-46 158.0 0.2 1.4e-46 157.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV PepSY_TM_1 PF13172.1 KFM06164.1 - 0.067 12.9 1.3 0.1 12.3 0.9 1.3 1 0 0 1 1 1 0 PepSY-associated TM helix DSPc PF00782.15 KFM06165.1 - 2.5e-25 88.5 0.0 2.8e-25 88.4 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFM06165.1 - 6.7e-05 22.3 0.1 7.1e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KFM06165.1 - 0.00084 19.4 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate IRF-3 PF10401.4 KFM06166.1 - 2.4e-62 209.7 0.1 3.3e-62 209.2 0.1 1.2 1 0 0 1 1 1 1 Interferon-regulatory factor 3 IRF PF00605.12 KFM06166.1 - 3.7e-47 158.6 0.8 9e-47 157.4 0.5 1.6 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor MH2 PF03166.9 KFM06166.1 - 0.0094 15.7 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 MH2 domain 5-FTHF_cyc-lig PF01812.15 KFM06167.1 - 1.9e-23 83.2 0.0 3.1e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family RRM_6 PF14259.1 KFM06167.1 - 1.3e-05 25.1 0.0 2.8e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFM06167.1 - 2.3e-05 23.9 0.0 9.5e-05 21.9 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM06167.1 - 3.1e-05 23.7 0.0 6.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fork_head PF00250.13 KFM06168.1 - 1.1e-47 159.9 0.1 1.3e-47 159.7 0.1 1.0 1 0 0 1 1 1 1 Fork head domain Fork_head PF00250.13 KFM06169.1 - 1.6e-45 153.0 0.0 1.8e-45 152.9 0.0 1.0 1 0 0 1 1 1 1 Fork head domain zf-DHHC PF01529.15 KFM06171.1 - 6.2e-39 133.1 9.3 6.2e-39 133.1 6.4 1.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase Hormone_recep PF00104.25 KFM06172.1 - 6.3e-39 133.2 0.0 9.4e-39 132.6 0.0 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFM06172.1 - 2.7e-30 104.3 18.1 4.6e-30 103.6 12.5 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Foamy_virus_ENV PF03408.9 KFM06172.1 - 0.012 13.2 2.1 0.016 12.8 1.4 1.1 1 0 0 1 1 1 0 Foamy virus envelope protein LCCL PF03815.14 KFM06173.1 - 1.2e-49 166.1 12.7 3.1e-26 91.1 0.1 2.9 3 0 0 3 3 3 2 LCCL domain CAP PF00188.21 KFM06173.1 - 1.6e-19 70.5 5.5 3.6e-19 69.4 3.8 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Rxt3 PF08642.5 KFM06173.1 - 3.4e-05 24.0 0.0 0.088 13.0 0.0 3.1 2 1 1 3 3 3 2 Histone deacetylation protein Rxt3 UCH PF00443.24 KFM06174.1 - 2e-42 145.1 0.0 3.3e-42 144.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFM06174.1 - 1.1e-16 61.1 0.1 3.1e-16 59.6 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase PAM2 PF07145.10 KFM06174.1 - 4.9e-05 22.5 0.0 0.00013 21.1 0.0 1.8 1 0 0 1 1 1 1 Ataxin-2 C-terminal region Kelch_1 PF01344.20 KFM06175.1 - 7.9e-45 150.1 12.5 6.7e-11 41.5 0.0 6.2 6 1 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 KFM06175.1 - 1.8e-32 110.1 4.1 4.4e-05 23.4 0.0 6.4 1 1 5 6 6 6 6 Kelch motif BTB PF00651.26 KFM06175.1 - 1.7e-27 95.6 0.5 8.6e-27 93.3 0.0 2.3 2 1 1 3 3 3 1 BTB/POZ domain Kelch_4 PF13418.1 KFM06175.1 - 7.4e-23 80.0 7.8 0.00013 21.6 0.0 5.8 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.10 KFM06175.1 - 1.4e-22 78.5 5.9 7.4e-05 22.3 0.2 6.6 6 0 0 6 6 6 4 Kelch motif BACK PF07707.10 KFM06175.1 - 3.5e-21 74.9 0.3 6.7e-21 74.0 0.2 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_3 PF13415.1 KFM06175.1 - 3.3e-19 68.4 0.7 0.0064 16.6 0.0 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 KFM06175.1 - 7.4e-17 60.9 3.6 5.9e-06 26.1 0.1 5.8 6 0 0 6 6 6 3 Kelch motif Cofilin_ADF PF00241.15 KFM06176.1 - 5.8e-11 42.3 0.1 6.9e-11 42.1 0.1 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein TLD PF07534.11 KFM06178.1 - 3.5e-38 130.7 0.1 5.4e-38 130.1 0.1 1.3 1 0 0 1 1 1 1 TLD E1-E2_ATPase PF00122.15 KFM06179.1 - 4e-74 248.5 0.4 4e-74 248.5 0.3 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFM06179.1 - 1.5e-44 151.7 6.4 1.5e-44 151.7 4.4 2.7 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFM06179.1 - 1.4e-25 90.9 0.0 7.5e-25 88.6 0.0 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFM06179.1 - 1.1e-19 69.6 0.0 2.7e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KFM06179.1 - 1.7e-16 59.9 0.1 1.3e-15 57.1 0.0 2.2 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KFM06179.1 - 3.3e-10 40.4 0.0 1.1e-09 38.7 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFM06179.1 - 0.00086 18.9 3.9 0.0013 18.3 1.5 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3329 PF11808.3 KFM06179.1 - 0.042 13.9 1.1 0.29 11.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) Rrf2 PF02082.15 KFM06179.1 - 0.051 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator Pox_F12L PF03337.8 KFM06179.1 - 0.2 9.5 0.0 0.32 8.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus F12L protein WAP PF00095.16 KFM06180.1 - 1.7e-06 27.8 15.2 1.7e-06 27.8 10.5 2.3 2 0 0 2 2 2 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Ion_trans PF00520.26 KFM06181.1 - 8.4e-29 100.2 3.0 1.8e-28 99.1 2.1 1.5 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.17 KFM06181.1 - 1.9e-25 88.8 0.0 4.8e-25 87.5 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.11 KFM06181.1 - 2.1e-12 46.5 4.9 2.9e-12 46.1 1.9 2.2 2 0 0 2 2 2 1 Ion channel CECR6_TMEM121 PF14997.1 KFM06181.1 - 0.034 13.7 1.0 0.063 12.8 0.6 1.6 1 1 0 1 1 1 0 CECR6/TMEM121 family HSBP1 PF06825.7 KFM06182.1 - 3.7e-13 48.8 8.1 2.8e-12 45.9 5.6 1.9 1 1 0 1 1 1 1 Heat shock factor binding protein 1 Tektin PF03148.9 KFM06182.1 - 0.035 12.6 0.2 0.037 12.5 0.1 1.0 1 0 0 1 1 1 0 Tektin family UPF0184 PF03670.8 KFM06182.1 - 0.095 12.8 0.3 0.11 12.7 0.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) FlaC_arch PF05377.6 KFM06182.1 - 0.12 12.2 0.9 0.15 11.9 0.1 1.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) TelA PF05816.6 KFM06182.1 - 0.13 10.9 0.9 0.14 10.7 0.6 1.0 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) MCD PF05292.6 KFM06183.1 - 6.7e-24 84.2 0.4 8.5e-24 83.9 0.2 1.1 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase (MCD) Cadherin PF00028.12 KFM06184.1 - 2.2e-70 232.9 6.9 5.2e-20 71.4 0.0 4.4 5 0 0 5 5 5 4 Cadherin domain MPP6 PF10175.4 KFM06185.1 - 1.7e-32 111.8 6.4 1.7e-32 111.8 4.4 1.7 2 0 0 2 2 2 1 M-phase phosphoprotein 6 FAM117 PF15388.1 KFM06185.1 - 0.06 12.5 0.4 0.078 12.1 0.1 1.3 1 1 0 1 1 1 0 Protein Family FAM117 Acetyltransf_2 PF00797.12 KFM06186.1 - 4.2e-92 308.0 0.5 4.9e-92 307.8 0.3 1.0 1 0 0 1 1 1 1 N-acetyltransferase Acetyltransf_2 PF00797.12 KFM06187.1 - 1.1e-88 296.8 0.1 1.3e-88 296.6 0.1 1.0 1 0 0 1 1 1 1 N-acetyltransferase DUF1250 PF06855.7 KFM06187.1 - 0.093 12.2 0.3 0.5 9.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1250) Acetyltransf_2 PF00797.12 KFM06188.1 - 2.3e-91 305.6 0.1 2.6e-91 305.4 0.1 1.0 1 0 0 1 1 1 1 N-acetyltransferase adh_short PF00106.20 KFM06189.1 - 7.3e-25 87.8 0.0 1e-24 87.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFM06189.1 - 4e-12 46.4 0.0 5.9e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KFM06189.1 - 1.3e-05 24.4 0.0 2.3e-05 23.7 0.0 1.3 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) KR PF08659.5 KFM06189.1 - 0.00022 20.9 0.0 0.00033 20.3 0.0 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 KFM06190.1 - 6.3e-72 241.6 0.0 8e-72 241.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KFM06190.1 - 1.8e-26 93.0 0.0 2.4e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KFM06190.1 - 4.6e-11 42.1 0.0 6.4e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KFM06190.1 - 1.2e-09 37.4 0.0 1.9e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KFM06190.1 - 3.1e-09 37.0 0.0 4.9e-09 36.4 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KFM06190.1 - 1.2e-07 30.9 0.2 3.9e-07 29.2 0.1 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein PI-PLC-X PF00388.14 KFM06191.1 - 3e-66 221.3 0.1 6.6e-66 220.1 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain SH2 PF00017.19 KFM06191.1 - 1.1e-46 156.4 0.3 9.3e-25 86.2 0.0 2.9 2 0 0 2 2 2 2 SH2 domain PI-PLC-Y PF00387.14 KFM06191.1 - 1.1e-41 141.5 0.0 3e-41 140.1 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 KFM06191.1 - 2.7e-14 52.7 0.0 2e-13 49.9 0.0 2.4 2 0 0 2 2 2 1 C2 domain SH3_1 PF00018.23 KFM06191.1 - 3.7e-13 48.6 0.1 1.2e-12 47.0 0.1 2.0 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFM06191.1 - 3.5e-12 45.7 0.1 1.4e-11 43.7 0.1 2.2 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 KFM06191.1 - 8.2e-08 32.3 2.5 0.031 14.4 0.1 4.0 3 0 0 3 3 3 3 PH domain EF-hand_like PF09279.6 KFM06191.1 - 9.8e-07 28.7 3.0 1.4e-06 28.2 0.1 2.6 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like SH3_2 PF07653.12 KFM06191.1 - 1e-05 24.8 0.0 2.7e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain GDPD PF03009.12 KFM06191.1 - 0.014 14.9 0.0 0.043 13.3 0.0 1.9 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family LRR_4 PF12799.2 KFM06192.1 - 5.5e-10 38.6 6.9 0.00012 21.6 0.4 4.0 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KFM06192.1 - 1.1e-05 25.0 10.2 0.46 10.7 0.0 5.8 6 0 0 6 6 6 3 Leucine Rich repeat LRR_8 PF13855.1 KFM06192.1 - 0.00011 21.9 8.8 0.01 15.5 0.9 3.5 2 1 0 2 2 2 2 Leucine rich repeat PH PF00169.24 KFM06192.1 - 0.059 13.5 0.1 0.34 11.1 0.0 2.2 2 0 0 2 2 2 0 PH domain RPE65 PF03055.10 KFM06193.1 - 6.9e-126 420.6 0.5 7.7e-126 420.4 0.4 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein GCV_H PF01597.14 KFM06194.1 - 6.6e-48 161.4 0.1 7.5e-48 161.2 0.1 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein zf-C2H2_4 PF13894.1 KFM06195.1 - 3.5e-05 23.8 11.3 0.089 13.1 0.2 4.0 2 1 1 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KFM06195.1 - 0.014 15.7 12.4 0.39 11.1 0.4 4.3 2 1 1 3 3 3 0 Zinc finger, C2H2 type CENP-N PF05238.8 KFM06196.1 - 1.8e-76 257.8 2.7 4.8e-76 256.3 1.9 1.6 1 1 0 1 1 1 1 Kinetochore protein CHL4 like Cmc1 PF08583.5 KFM06197.1 - 3.1e-16 58.9 4.3 3.5e-16 58.7 2.9 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3452 PF11934.3 KFM06197.1 - 0.023 14.0 0.0 0.024 13.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) DUF755 PF05501.6 KFM06197.1 - 0.026 14.5 1.2 0.03 14.4 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF217 PF02697.9 KFM06197.1 - 0.04 14.1 0.1 0.057 13.6 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized ACR, COG1753 DUF1903 PF08991.5 KFM06197.1 - 0.28 11.3 3.3 1.5 9.0 2.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1903) GCK PF07802.6 KFM06197.1 - 0.78 9.8 3.9 9.6 6.4 0.2 2.2 1 1 1 2 2 2 0 GCK domain ECH PF00378.15 KFM06198.1 - 2.8e-34 118.3 0.0 3.5e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Chromo PF00385.19 KFM06198.1 - 5.3e-17 61.2 1.8 1.2e-16 60.0 1.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain CCT PF06203.9 KFM06198.1 - 1.2 8.7 6.1 1.3 8.6 0.4 2.7 2 0 0 2 2 2 0 CCT motif Robl_LC7 PF03259.12 KFM06199.1 - 4.1e-18 64.7 0.0 4.5e-18 64.6 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain Yae1_N PF09811.4 KFM06200.1 - 2e-17 62.4 64.3 1.5e+04 -25.1 44.6 5.7 1 1 0 1 1 1 0 Essential protein Yae1, N terminal adh_short PF00106.20 KFM06201.1 - 3.7e-19 69.2 0.1 4.9e-19 68.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFM06201.1 - 5.7e-09 35.8 0.1 9e-09 35.2 0.1 1.2 1 0 0 1 1 1 1 KR domain WW PF00397.21 KFM06201.1 - 1.2e-08 34.5 5.3 2.1e-07 30.6 0.3 2.5 2 0 0 2 2 2 2 WW domain adh_short_C2 PF13561.1 KFM06201.1 - 3.7e-07 30.1 0.0 6.1e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KFM06201.1 - 0.00016 21.7 0.1 0.00075 19.5 0.1 2.0 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFM06201.1 - 0.001 18.5 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PerB PF06590.6 KFM06201.1 - 0.11 12.8 0.0 0.26 11.5 0.0 1.6 2 0 0 2 2 2 0 PerB protein HAD PF12710.2 KFM06201.1 - 0.12 12.4 0.0 0.33 11.0 0.0 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Lectin_C PF00059.16 KFM06202.1 - 4.3e-18 65.8 0.2 6.6e-18 65.2 0.1 1.3 1 0 0 1 1 1 1 Lectin C-type domain Chordopox_A33R PF05966.7 KFM06202.1 - 0.0017 17.1 0.1 0.0024 16.6 0.0 1.2 1 0 0 1 1 1 1 Chordopoxvirus A33R protein Lipoprotein_15 PF03640.10 KFM06202.1 - 0.04 13.3 0.0 0.33 10.4 0.0 2.1 2 0 0 2 2 2 0 Secreted repeat of unknown function GPS PF01825.16 KFM06202.1 - 0.088 12.9 0.2 0.19 11.8 0.2 1.5 1 0 0 1 1 1 0 Latrophilin/CL-1-like GPS domain ADH_zinc_N_2 PF13602.1 KFM06203.1 - 7.9e-13 49.4 0.0 2.3e-12 47.8 0.0 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFM06203.1 - 6.7e-10 38.7 0.0 1.8e-09 37.3 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFM06203.1 - 8.1e-10 38.3 0.0 2.5e-09 36.7 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DapB_N PF01113.15 KFM06203.1 - 0.081 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NUDIX PF00293.23 KFM06204.1 - 3.5e-16 59.0 0.0 4.8e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain ADAM_spacer1 PF05986.9 KFM06206.1 - 3e-34 117.2 0.0 6.4e-34 116.2 0.0 1.6 1 0 0 1 1 1 1 ADAM-TS Spacer 1 TSP_1 PF00090.14 KFM06206.1 - 1.1e-32 111.8 81.9 6.6e-11 42.1 5.6 7.9 6 1 0 6 6 6 6 Thrombospondin type 1 domain Reprolysin PF01421.14 KFM06206.1 - 5.4e-30 104.4 0.1 1.1e-29 103.4 0.0 1.5 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.14 KFM06206.1 - 1.1e-29 102.8 0.6 1.9e-29 102.0 0.4 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide PLAC PF08686.6 KFM06206.1 - 5e-11 42.6 8.1 5e-11 42.6 5.6 4.5 4 0 0 4 4 4 1 PLAC (protease and lacunin) domain Reprolysin_2 PF13574.1 KFM06206.1 - 6.9e-11 42.5 0.1 2.1e-10 40.9 0.1 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KFM06206.1 - 1.4e-10 41.4 1.1 3e-10 40.3 0.0 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KFM06206.1 - 2.7e-08 33.5 0.2 3.2e-07 30.1 0.0 2.3 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KFM06206.1 - 4.3e-08 33.7 0.2 5.8e-07 30.0 0.0 2.5 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Cadherin PF00028.12 KFM06207.1 - 3.4e-84 277.2 1.5 9.2e-18 64.2 0.0 5.2 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.12 KFM06207.1 - 2.8e-16 59.8 0.1 5.7e-16 58.8 0.1 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.7 KFM06207.1 - 1.2e-05 24.8 0.0 0.4 10.2 0.0 3.7 3 0 0 3 3 3 2 Cadherin-like Cadherin_pro PF08758.6 KFM06207.1 - 0.17 11.6 0.0 3 7.6 0.0 2.8 2 1 0 2 2 2 0 Cadherin prodomain like Ten_N PF06484.7 KFM06208.1 - 3.1e-28 98.9 4.1 3.4e-28 98.8 2.9 1.0 1 0 0 1 1 1 1 Teneurin Intracellular Region dCMP_cyt_deam_1 PF00383.17 KFM06210.1 - 2.1e-27 94.7 0.1 3e-27 94.2 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DUF1293 PF06950.6 KFM06210.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1293) WW PF00397.21 KFM06211.1 - 6.1e-07 29.1 0.2 1.2e-06 28.2 0.2 1.5 1 0 0 1 1 1 1 WW domain C2 PF00168.25 KFM06211.1 - 0.043 13.6 0.0 0.092 12.6 0.0 1.6 1 0 0 1 1 1 0 C2 domain PMP22_Claudin PF00822.15 KFM06212.1 - 8.3e-24 84.1 0.5 9.9e-24 83.8 0.4 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFM06212.1 - 3e-08 33.5 1.1 4.8e-08 32.8 0.4 1.5 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.7 KFM06212.1 - 0.097 11.9 0.2 0.17 11.1 0.2 1.4 1 0 0 1 1 1 0 Clc-like Spore_YabQ PF09578.5 KFM06212.1 - 0.31 11.0 0.0 0.31 11.0 0.0 2.2 3 0 0 3 3 3 0 Spore cortex protein YabQ (Spore_YabQ) DUF4131 PF13567.1 KFM06212.1 - 2 7.7 5.7 12 5.2 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) DUF3469 PF11952.3 KFM06213.1 - 9.8e-12 44.4 0.2 3.7e-08 32.9 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3469) ING PF12998.2 KFM06214.1 - 4.8e-13 49.2 4.5 4.8e-13 49.2 3.1 1.9 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 KFM06214.1 - 2.9e-10 39.6 7.9 2.9e-10 39.6 5.5 2.2 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 KFM06214.1 - 0.0086 15.3 3.4 0.023 14.0 2.4 1.7 1 0 0 1 1 1 1 PHD-finger zf-RING-like PF08746.6 KFM06214.1 - 0.011 15.6 6.7 0.31 11.0 3.9 2.6 2 0 0 2 2 2 0 RING-like domain zf-HC5HC2H PF13771.1 KFM06214.1 - 0.22 11.6 6.6 0.049 13.7 1.7 2.1 2 1 0 2 2 2 0 PHD-like zinc-binding domain DDHD PF02862.12 KFM06214.1 - 2.6 7.7 6.3 3.6 7.3 4.4 1.2 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.7 KFM06214.1 - 2.8 7.7 8.9 3.6 7.3 6.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RWD PF05773.17 KFM06215.1 - 8.4e-15 54.6 0.1 2.1e-14 53.3 0.0 1.6 2 0 0 2 2 2 1 RWD domain Inhibitor_I71 PF12628.2 KFM06215.1 - 0.013 15.1 0.7 0.017 14.7 0.5 1.1 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor Gryzun PF07919.7 KFM06216.1 - 2.8e-113 379.1 0.2 3.7e-113 378.7 0.1 1.2 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 KFM06216.1 - 4.4e-76 255.6 0.8 8.4e-76 254.7 0.6 1.5 1 0 0 1 1 1 1 Foie gras liver health family 1 Gryzun-like PF12742.2 KFM06216.1 - 1.7e-24 85.4 0.1 8.9e-24 83.0 0.0 2.1 2 0 0 2 2 2 1 Gryzun, putative Golgi trafficking Stork_head PF10264.4 KFM06217.1 - 1.4e-38 130.9 0.1 4e-38 129.4 0.1 1.8 1 0 0 1 1 1 1 Winged helix Storkhead-box1 domain IRF PF00605.12 KFM06218.1 - 3.7e-47 158.6 1.4 6.8e-47 157.8 1.0 1.4 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor Heme_oxygenase PF01126.15 KFM06218.1 - 0.067 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Heme oxygenase CENP-U PF13097.1 KFM06219.1 - 2.5e-42 144.7 12.6 2.5e-42 144.7 8.7 2.0 2 0 0 2 2 2 1 CENP-A nucleosome associated complex (NAC) subunit eIF3_N PF09440.5 KFM06219.1 - 0.062 13.4 1.7 0.14 12.3 1.2 1.5 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain Tox-ART-HYE1 PF15634.1 KFM06219.1 - 0.11 11.4 2.7 0.2 10.6 1.9 1.4 1 0 0 1 1 1 0 HYE1 signature containing ADP-ribosyltransferase Mt_ATP-synt_B PF05405.9 KFM06219.1 - 0.91 8.9 10.0 0.072 12.5 3.5 1.8 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) CorA PF01544.13 KFM06219.1 - 2.5 7.0 6.4 1.2 8.0 1.1 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Aft1_HRR PF11787.3 KFM06219.1 - 5.7 8.0 7.0 2.3 9.3 0.8 2.5 1 1 0 2 2 2 0 Aft1 HRR domain DUF4613 PF15390.1 KFM06219.1 - 6.1 4.8 10.8 0.61 8.1 2.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4613) IncA PF04156.9 KFM06219.1 - 7.7 6.0 19.6 2.8 7.5 10.7 2.3 1 1 1 2 2 2 0 IncA protein Mito_carr PF00153.22 KFM06220.1 - 6.2e-59 195.7 3.1 1.5e-22 79.0 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Nexin_C PF08628.7 KFM06221.1 - 3.7e-33 113.9 0.1 1.9e-32 111.6 0.1 2.3 1 0 0 1 1 1 1 Sorting nexin C terminal PXA PF02194.10 KFM06221.1 - 5.9e-29 100.9 3.0 5.9e-29 100.9 2.1 3.9 3 1 0 3 3 3 1 PXA domain RGS PF00615.14 KFM06221.1 - 2.1e-20 73.0 1.6 2.1e-20 73.0 1.1 3.1 3 0 0 3 3 3 1 Regulator of G protein signaling domain PX PF00787.19 KFM06221.1 - 1.6e-19 69.7 0.1 1.1e-18 67.0 0.1 2.6 1 0 0 1 1 1 1 PX domain Isy1 PF06246.7 KFM06221.1 - 0.041 13.2 0.1 0.041 13.2 0.1 3.1 3 1 0 3 3 3 0 Isy1-like splicing family Sel1 PF08238.7 KFM06222.1 - 1.1e-30 105.3 21.4 5.4e-07 30.0 0.1 5.8 6 0 0 6 6 6 5 Sel1 repeat TPR_6 PF13174.1 KFM06222.1 - 0.00011 22.4 8.1 4.8 7.8 0.1 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TENA_THI-4 PF03070.11 KFM06222.1 - 0.038 13.7 0.0 0.21 11.2 0.1 1.9 1 1 1 2 2 2 0 TENA/THI-4/PQQC family TPR_8 PF13181.1 KFM06222.1 - 0.1 12.4 10.2 9.8 6.2 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.1 KFM06222.1 - 0.62 9.7 12.7 5.1 6.8 0.6 4.3 2 2 3 5 5 5 0 TPR repeat TPR_2 PF07719.12 KFM06222.1 - 8.9 6.5 20.8 1.9 8.5 0.1 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat Peptidase_C78 PF07910.8 KFM06223.1 - 9.7e-54 181.7 0.2 1.9e-53 180.8 0.1 1.5 2 0 0 2 2 2 1 Peptidase family C78 DUF4586 PF15239.1 KFM06224.1 - 4.8e-110 367.8 11.6 5.6e-110 367.6 8.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) PDZ PF00595.19 KFM06225.1 - 1.2e-16 60.6 0.0 3.3e-16 59.2 0.0 1.8 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) LIM PF00412.17 KFM06225.1 - 1.6e-13 50.4 3.9 3.1e-13 49.5 2.7 1.4 1 0 0 1 1 1 1 LIM domain PDZ_2 PF13180.1 KFM06225.1 - 8.7e-05 22.3 0.0 0.00026 20.8 0.0 1.7 2 0 0 2 2 2 1 PDZ domain SH3_1 PF00018.23 KFM06226.1 - 3.7e-43 144.6 0.3 1.7e-14 52.9 0.0 3.5 3 0 0 3 3 3 3 SH3 domain SH3_9 PF14604.1 KFM06226.1 - 4.1e-42 141.5 1.9 2.1e-14 52.7 0.1 4.2 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 KFM06226.1 - 6.1e-31 105.6 0.7 3e-14 52.2 0.0 3.5 3 0 0 3 3 3 3 Variant SH3 domain Sorb PF02208.11 KFM06226.1 - 2.6e-29 100.3 8.5 2.7e-29 100.2 1.4 2.6 2 0 0 2 2 2 1 Sorbin homologous domain DUF3719 PF12516.3 KFM06227.1 - 5.2e-22 77.1 0.1 2e-21 75.3 0.0 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3719) p450 PF00067.17 KFM06228.1 - 2.4e-127 425.2 0.0 2.7e-127 425.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peripla_BP_1 PF00532.16 KFM06228.1 - 0.12 11.6 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family Trypsin PF00089.21 KFM06229.1 - 1.5e-72 243.8 0.0 2.1e-72 243.2 0.0 1.3 1 0 0 1 1 1 1 Trypsin PAN_1 PF00024.21 KFM06229.1 - 1.2e-28 98.6 33.7 5.7e-09 35.6 0.5 4.8 5 0 0 5 5 5 4 PAN domain PAN_4 PF14295.1 KFM06229.1 - 1.2e-16 60.0 25.8 3.8e-05 23.3 0.6 5.8 5 1 1 6 6 6 4 PAN domain DUF1986 PF09342.6 KFM06229.1 - 1.8e-05 24.1 0.1 5.1e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 KFM06229.1 - 0.0069 16.3 0.0 0.019 14.9 0.0 1.8 1 0 0 1 1 1 1 Trypsin-like peptidase domain 7tm_1 PF00001.16 KFM06230.1 - 2.5e-43 148.0 21.4 3e-43 147.8 14.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 KFM06230.1 - 6.6e-05 22.1 19.7 9.8e-05 21.5 13.7 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF4233 PF14017.1 KFM06230.1 - 0.47 10.3 14.3 2.5 8.0 0.7 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4233) PgaD PF13994.1 KFM06230.1 - 1 8.8 6.1 0.33 10.4 1.5 2.0 1 1 1 2 2 2 0 PgaD-like protein Cadherin PF00028.12 KFM06231.1 - 0 1695.4 93.8 1.1e-23 83.3 0.3 34.3 34 0 0 34 34 34 34 Cadherin domain Laminin_G_2 PF02210.19 KFM06231.1 - 3.7e-25 88.4 0.4 1.7e-24 86.2 0.3 2.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.18 KFM06231.1 - 1.8e-18 66.8 0.0 1.1e-17 64.2 0.0 2.5 1 0 0 1 1 1 1 Laminin G domain Cadherin_2 PF08266.7 KFM06231.1 - 1.6e-17 62.8 1.3 9.1 5.9 0.0 16.9 22 0 0 22 22 22 2 Cadherin-like EGF PF00008.22 KFM06231.1 - 1.5e-11 43.9 59.7 5.1e-05 23.1 4.4 4.8 5 0 0 5 5 5 3 EGF-like domain EGF_CA PF07645.10 KFM06231.1 - 7.9e-06 25.7 10.4 7.9e-06 25.7 7.2 4.5 3 1 1 4 4 4 1 Calcium-binding EGF domain Laminin_G_3 PF13385.1 KFM06231.1 - 9.5e-06 25.9 0.1 3.2e-05 24.2 0.1 1.9 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily NfeD PF01957.13 KFM06231.1 - 0.47 10.5 0.1 1.1 9.3 0.0 1.6 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding MscS_TM PF12794.2 KFM06231.1 - 6.8 5.2 0.0 10 4.6 0.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF2079 PF09852.4 KFM06231.1 - 8.2 5.0 0.0 61 2.1 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2079) FRG1 PF06229.7 KFM06232.1 - 4.8e-82 274.0 1.1 4.8e-82 274.0 0.8 1.5 2 0 0 2 2 2 1 FRG1-like family Fascin PF06268.8 KFM06232.1 - 1.4e-08 34.8 0.0 5.3e-08 32.9 0.0 1.9 1 1 0 1 1 1 1 Fascin domain DUF569 PF04601.8 KFM06232.1 - 0.0002 20.8 0.1 0.0017 17.7 0.0 2.5 1 1 0 2 2 2 1 Protein of unknown function (DUF569) DUF1754 PF08555.5 KFM06232.1 - 0.048 14.2 7.7 0.048 14.2 5.3 2.8 2 1 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) CBAH PF02275.13 KFM06233.1 - 3e-34 118.9 0.0 4.2e-34 118.3 0.0 1.2 1 0 0 1 1 1 1 Linear amide C-N hydrolases, choloylglycine hydrolase family NAAA-beta PF15508.1 KFM06233.1 - 3e-33 114.0 0.0 5.8e-33 113.1 0.0 1.5 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase TFIIE_alpha PF02002.12 KFM06234.1 - 7.7e-29 99.2 1.9 1.7e-28 98.1 1.3 1.6 1 0 0 1 1 1 1 TFIIE alpha subunit TFIIE-A_C-term PF11521.3 KFM06234.1 - 2.5e-22 78.6 0.9 2.5e-22 78.6 0.6 1.9 2 0 0 2 2 2 1 C-terminal general transcription factor TFIIE alpha TF_Zn_Ribbon PF08271.7 KFM06234.1 - 1.4e-06 27.4 0.7 3.3e-06 26.3 0.5 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.6 KFM06234.1 - 0.021 14.4 0.6 0.047 13.3 0.4 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Elf1 PF05129.8 KFM06234.1 - 0.12 12.0 2.1 0.42 10.3 1.4 1.9 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like PyrI_C PF02748.10 KFM06234.1 - 0.14 11.6 3.7 0.17 11.3 1.5 2.0 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn-ribbon_8 PF09723.5 KFM06234.1 - 0.34 10.8 2.5 12 5.9 0.3 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-Di19 PF05605.7 KFM06234.1 - 0.38 10.9 1.5 23 5.1 0.1 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Fibrinogen_C PF00147.13 KFM06236.1 - 7.9e-80 267.8 13.2 9.6e-80 267.5 9.2 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain ParA PF10609.4 KFM06237.1 - 0.059 13.2 0.1 9 6.2 0.0 2.9 2 0 0 2 2 2 0 ParA/MinD ATPase like FUSC PF04632.7 KFM06237.1 - 0.15 10.4 0.4 0.26 9.6 0.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tetraspannin PF00335.15 KFM06238.1 - 0.012 14.9 1.0 0.011 15.0 0.7 1.1 1 0 0 1 1 1 0 Tetraspanin family I-set PF07679.11 KFM06239.1 - 1.3e-12 47.3 0.1 1.8e-06 27.7 0.0 2.8 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM06239.1 - 3.7e-12 46.1 1.6 5.5e-05 23.2 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 KFM06239.1 - 4.8e-07 30.1 0.8 0.01 16.2 0.0 4.2 3 1 0 3 3 3 2 Immunoglobulin domain ig PF00047.20 KFM06239.1 - 1e-06 28.7 0.2 0.022 14.8 0.0 4.4 3 2 0 3 3 3 2 Immunoglobulin domain V-set PF07686.12 KFM06239.1 - 0.001 18.9 1.8 4.2 7.2 0.4 3.9 2 2 0 2 2 2 2 Immunoglobulin V-set domain AA_permease_2 PF13520.1 KFM06240.1 - 5.5e-51 173.4 31.8 5.5e-51 173.4 22.1 2.3 2 1 0 2 2 2 1 Amino acid permease AA_permease PF00324.16 KFM06240.1 - 7.9e-36 123.4 30.0 7.9e-36 123.4 20.8 2.0 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.1 KFM06240.1 - 3.9e-24 84.2 6.3 3.9e-24 84.2 4.4 4.1 5 0 0 5 5 5 1 C-terminus of AA_permease Myotub-related PF06602.9 KFM06241.1 - 1.4e-143 477.9 0.2 1.9e-143 477.5 0.1 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.15 KFM06241.1 - 0.0009 18.8 0.0 0.0023 17.5 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFM06241.1 - 0.0023 17.2 0.0 0.005 16.2 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KFM06241.1 - 0.0085 16.3 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family GRAM PF02893.15 KFM06241.1 - 0.04 13.4 0.0 0.083 12.4 0.0 1.5 1 0 0 1 1 1 0 GRAM domain Mod_r PF07200.8 KFM06242.1 - 5.9e-47 159.3 16.3 7.4e-47 159.0 11.3 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein UEV PF05743.8 KFM06242.1 - 0.0019 17.8 4.4 0.0048 16.5 0.4 2.7 3 0 0 3 3 3 1 UEV domain SWI-SNF_Ssr4 PF08549.5 KFM06242.1 - 0.041 12.2 2.1 1.2 7.3 0.0 2.2 1 1 1 2 2 2 0 Fungal domain of unknown function (DUF1750) Phage_Gp23 PF10669.4 KFM06242.1 - 0.082 13.0 1.9 1.8 8.6 0.1 2.4 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DivIVA PF05103.8 KFM06242.1 - 0.95 9.5 8.0 3.1 7.8 5.5 1.8 1 1 0 1 1 1 0 DivIVA protein CAF1 PF04857.15 KFM06243.1 - 1.7e-70 237.3 0.1 2.6e-70 236.7 0.0 1.3 1 1 0 1 1 1 1 CAF1 family ribonuclease EF-hand_8 PF13833.1 KFM06244.1 - 8.8e-20 70.0 10.5 2.9e-11 42.8 0.0 6.2 5 2 1 6 6 6 3 EF-hand domain pair EF-hand_6 PF13405.1 KFM06244.1 - 3.3e-10 38.9 13.1 0.00028 20.5 0.3 6.6 8 0 0 8 8 8 2 EF-hand domain EF-hand_7 PF13499.1 KFM06244.1 - 7.4e-10 38.8 10.2 0.00014 21.9 0.3 5.4 4 3 0 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.27 KFM06244.1 - 9.1e-10 37.1 20.0 8.1e-05 21.6 0.5 6.9 8 0 0 8 8 8 2 EF hand EF-hand_4 PF12763.2 KFM06244.1 - 0.0043 16.7 0.8 0.044 13.5 0.0 2.9 2 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.1 KFM06244.1 - 0.8 9.1 14.4 2.2 7.7 0.1 5.6 8 0 0 8 8 8 0 EF hand FGF PF00167.13 KFM06245.1 - 1.1e-31 109.1 0.0 1.3e-31 108.9 0.0 1.0 1 0 0 1 1 1 1 Fibroblast growth factor SIR2 PF02146.12 KFM06245.1 - 0.083 12.6 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Sir2 family OST3_OST6 PF04756.8 KFM06247.1 - 4.3e-47 159.6 0.0 5.8e-47 159.2 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 KFM06247.1 - 8.8e-06 25.3 0.0 1.3e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DUF4131 PF13567.1 KFM06247.1 - 0.034 13.5 0.1 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) YhhN PF07947.9 KFM06247.1 - 0.069 12.5 0.5 0.14 11.5 0.0 1.6 2 0 0 2 2 2 0 YhhN-like protein Thioredoxin_2 PF13098.1 KFM06247.1 - 0.15 12.3 0.1 0.82 9.8 0.1 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain DUF3049 PF11250.3 KFM06248.1 - 0.079 12.7 0.5 0.74 9.6 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3049) Sarcoglycan_1 PF04790.8 KFM06249.1 - 3.4e-78 262.4 0.0 4.2e-78 262.1 0.0 1.1 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein DUF2345 PF10106.4 KFM06249.1 - 1.7e-05 24.4 0.1 0.0057 16.2 0.0 2.6 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2345) SR-25 PF10500.4 KFM06249.1 - 3.1 7.1 8.3 5.3 6.4 5.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein START PF01852.14 KFM06253.1 - 8e-47 159.2 1.4 8.3e-47 159.1 0.0 1.7 2 0 0 2 2 2 1 START domain RhoGAP PF00620.22 KFM06253.1 - 1e-41 142.1 0.7 3.8e-41 140.2 0.7 1.8 2 0 0 2 2 2 1 RhoGAP domain Methyltransf_11 PF08241.7 KFM06254.1 - 6.4e-15 55.4 0.0 1.6e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFM06254.1 - 5.9e-08 32.5 0.0 1.5e-07 31.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFM06254.1 - 7.8e-07 28.7 0.0 1.5e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFM06254.1 - 4e-06 27.2 0.0 1.6e-05 25.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFM06254.1 - 7.8e-06 25.1 0.0 4.8e-05 22.5 0.0 2.2 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.10 KFM06254.1 - 1e-05 25.2 0.0 4.7e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_25 PF13649.1 KFM06254.1 - 1.2e-05 25.5 0.1 5.7e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 KFM06254.1 - 0.00013 21.1 0.1 0.0082 15.2 0.1 2.6 2 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 KFM06254.1 - 0.0039 17.2 0.1 0.01 15.8 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_9 PF08003.6 KFM06254.1 - 0.013 14.2 0.0 3.5 6.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.2 KFM06254.1 - 0.028 15.0 0.2 0.17 12.5 0.1 2.3 2 1 0 2 2 2 0 Methyltransferase domain SAICAR_synt PF01259.13 KFM06255.1 - 3.7e-83 278.4 0.1 4.7e-83 278.1 0.1 1.1 1 0 0 1 1 1 1 SAICAR synthetase AIRC PF00731.15 KFM06255.1 - 1.1e-35 122.1 0.0 1.9e-35 121.3 0.0 1.4 1 0 0 1 1 1 1 AIR carboxylase Myb_DNA-bind_4 PF13837.1 KFM06256.1 - 1.8e-20 72.8 1.4 2.3e-20 72.4 1.0 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 KFM06256.1 - 0.00033 20.4 2.9 0.00076 19.3 2.0 1.6 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.2 KFM06256.1 - 0.0013 19.2 0.8 0.0016 19.0 0.6 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFM06256.1 - 0.0086 16.1 2.0 0.019 15.0 1.4 1.5 1 1 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 KFM06256.1 - 0.15 12.2 1.0 0.24 11.6 0.4 1.5 1 1 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like GATase_2 PF00310.16 KFM06257.1 - 4.2e-25 88.2 0.0 2.6e-24 85.6 0.0 1.9 1 1 1 2 2 2 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 KFM06257.1 - 6.5e-17 61.7 0.0 1.3e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KFM06257.1 - 2e-15 56.6 0.0 3.1e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 KFM06257.1 - 7.8e-13 48.2 0.0 1.3e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 KFM06257.1 - 1.4e-07 30.4 0.0 2.2e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II AMP-binding PF00501.23 KFM06258.1 - 5.5e-48 163.3 0.0 7.7e-48 162.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PQQ_3 PF13570.1 KFM06258.1 - 2.3e-36 123.0 0.3 4.2e-06 26.8 0.1 9.2 9 0 0 9 9 9 6 PQQ-like domain PQQ_2 PF13360.1 KFM06258.1 - 5.9e-24 84.8 0.0 2.1e-08 33.9 0.0 4.7 2 1 1 4 4 4 3 PQQ-like domain PQQ PF01011.16 KFM06258.1 - 1.6e-16 58.8 6.1 0.011 15.2 0.0 7.9 8 0 0 8 8 8 6 PQQ enzyme repeat AMP-binding_C PF13193.1 KFM06258.1 - 8.2e-07 29.8 0.0 2e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.20 KFM06258.1 - 0.0016 18.6 0.0 0.0047 17.1 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Sec3_C PF09763.4 KFM06259.1 - 1.1e-213 711.3 28.0 1.4e-213 710.9 19.4 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 KFM06259.1 - 5.2e-29 99.9 2.1 1.8e-28 98.2 1.4 2.0 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH FlaC_arch PF05377.6 KFM06259.1 - 0.12 12.2 3.2 2.1 8.3 0.7 3.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF972 PF06156.8 KFM06259.1 - 7.1 7.0 10.3 2 8.8 1.8 3.7 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Phosducin PF02114.11 KFM06261.1 - 7e-16 57.7 0.1 8.5e-16 57.4 0.1 1.0 1 0 0 1 1 1 1 Phosducin PRD_Mga PF08270.6 KFM06261.1 - 0.07 12.3 0.0 0.091 12.0 0.0 1.1 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) PRD domain PAS_11 PF14598.1 KFM06262.1 - 6e-27 93.7 0.0 6.8e-23 80.7 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.6 KFM06262.1 - 8.1e-16 57.9 1.3 6.9e-15 54.9 0.1 2.9 3 0 0 3 3 3 1 PAS fold PAS PF00989.19 KFM06262.1 - 1.1e-09 38.1 0.0 4.3e-07 29.6 0.0 2.7 2 0 0 2 2 2 2 PAS fold HLH PF00010.21 KFM06262.1 - 3.8e-09 36.0 0.4 1e-08 34.7 0.3 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.1 KFM06262.1 - 0.0019 18.5 0.0 0.06 13.7 0.0 2.9 3 0 0 3 3 3 1 PAS domain INO80_Ies4 PF08193.6 KFM06262.1 - 0.02 14.8 7.8 0.031 14.2 5.4 1.2 1 0 0 1 1 1 0 INO80 complex subunit Ies4 RNA_pol_Rpb4 PF03874.11 KFM06262.1 - 0.17 11.8 6.7 0.53 10.3 0.2 3.0 3 0 0 3 3 3 0 RNA polymerase Rpb4 UPF0016 PF01169.14 KFM06263.1 - 2.6e-43 146.0 20.3 3.7e-24 84.6 2.8 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Med9 PF07544.8 KFM06263.1 - 0.26 11.0 1.9 0.41 10.4 1.3 1.2 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 IncA PF04156.9 KFM06263.1 - 0.75 9.3 0.0 0.75 9.3 0.0 2.5 3 0 0 3 3 3 0 IncA protein Steroid_dh PF02544.11 KFM06264.1 - 3.8e-21 75.4 5.7 6.8e-21 74.6 3.9 1.6 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase FB_lectin PF07367.6 KFM06264.1 - 0.0029 17.2 0.1 0.0055 16.3 0.1 1.4 1 0 0 1 1 1 1 Fungal fruit body lectin Pkinase_Tyr PF07714.12 KFM06265.1 - 8e-103 343.0 0.0 1.1e-102 342.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM06265.1 - 4e-46 157.2 0.0 5.9e-33 114.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain I-set PF07679.11 KFM06265.1 - 4e-24 84.2 0.1 2.5e-15 56.0 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM06265.1 - 1.3e-21 76.5 1.3 1.2e-08 34.9 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain Ig_3 PF13927.1 KFM06265.1 - 5.2e-17 62.0 1.9 1.6e-09 38.1 0.1 3.5 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.20 KFM06265.1 - 4.3e-13 49.1 0.1 4.1e-09 36.4 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.12 KFM06265.1 - 1.9e-07 30.9 0.3 0.023 14.5 0.0 3.4 3 2 0 3 3 3 2 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM06265.1 - 0.00024 20.9 0.1 0.0011 18.7 0.0 2.1 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Kinase-like PF14531.1 KFM06265.1 - 0.14 11.0 0.0 0.27 10.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pkinase_Tyr PF07714.12 KFM06267.1 - 1.5e-104 348.7 0.0 2.1e-104 348.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM06267.1 - 4.3e-44 150.6 0.0 1.4e-30 106.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain I-set PF07679.11 KFM06267.1 - 1.8e-23 82.1 2.4 2.1e-08 33.8 0.0 5.8 5 1 1 6 6 6 4 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM06267.1 - 1.5e-19 69.8 3.1 7e-05 22.8 0.0 5.3 4 1 1 5 5 5 3 Immunoglobulin domain Ig_3 PF13927.1 KFM06267.1 - 2.7e-12 47.0 11.2 0.00023 21.6 0.0 4.9 5 0 0 5 5 5 3 Immunoglobulin domain V-set PF07686.12 KFM06267.1 - 1.4e-06 28.1 5.6 0.22 11.4 0.0 5.8 5 1 0 5 5 5 2 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM06267.1 - 0.00019 21.2 0.1 0.45 10.4 0.0 3.0 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain ig PF00047.20 KFM06267.1 - 0.066 13.3 8.0 0.097 12.8 0.0 4.6 5 0 0 5 5 5 0 Immunoglobulin domain APH PF01636.18 KFM06267.1 - 0.17 11.5 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family PDZ PF00595.19 KFM06269.1 - 3.3e-62 206.6 4.1 2e-17 63.1 0.0 4.3 4 0 0 4 4 4 4 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM06269.1 - 1.2e-17 63.5 0.1 0.0014 18.4 0.0 4.3 4 0 0 4 4 4 4 PDZ domain zf-C3HC4 PF00097.20 KFM06269.1 - 2.6e-06 26.9 6.5 9.5e-06 25.1 4.5 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Tricorn_PDZ PF14685.1 KFM06269.1 - 7.3e-06 25.6 0.3 4.2 7.2 0.0 4.3 4 0 0 4 4 4 1 Tricorn protease PDZ domain zf-RING_2 PF13639.1 KFM06269.1 - 1.6e-05 24.6 6.8 7e-05 22.5 4.7 2.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KFM06269.1 - 0.00014 21.5 5.1 0.00014 21.5 3.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFM06269.1 - 0.00017 21.4 7.3 0.00069 19.4 5.0 2.2 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 KFM06269.1 - 0.00078 19.4 5.6 0.00078 19.4 3.9 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM06269.1 - 0.0054 16.3 2.3 0.0054 16.3 1.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFM06269.1 - 0.0073 16.3 3.4 0.042 13.9 2.4 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KFM06269.1 - 1.5 8.5 11.3 0.11 12.1 3.7 2.3 2 0 0 2 2 2 0 RING-type zinc-finger Fip1 PF05182.8 KFM06270.1 - 3.6e-26 90.1 1.0 7.7e-26 89.1 0.7 1.6 1 0 0 1 1 1 1 Fip1 motif Ras PF00071.17 KFM06272.1 - 1.6e-17 63.3 0.0 2.2e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM06272.1 - 5e-09 36.6 0.0 7.8e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein DUF2819 PF10995.3 KFM06272.1 - 0.013 14.2 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2819) MMR_HSR1 PF01926.18 KFM06272.1 - 0.025 14.5 0.0 0.05 13.5 0.0 1.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase UCH PF00443.24 KFM06273.1 - 9.1e-69 231.5 9.3 1.1e-68 231.3 6.5 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFM06273.1 - 4.1e-37 128.2 9.4 5e-37 127.9 6.5 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3510 PF12022.3 KFM06273.1 - 0.047 13.7 1.2 0.095 12.8 0.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3510) Sarcoglycan_1 PF04790.8 KFM06275.1 - 3.6e-75 252.5 0.3 4.3e-75 252.2 0.2 1.0 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein LRR_8 PF13855.1 KFM06276.1 - 8.5e-22 76.6 21.7 7.9e-14 51.1 1.3 3.9 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 KFM06276.1 - 1.3e-18 66.1 32.4 3.6e-07 29.6 1.0 5.2 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM06276.1 - 2.6e-12 44.9 25.9 0.087 12.9 0.0 8.1 8 0 0 8 8 8 6 Leucine Rich Repeat LRR_6 PF13516.1 KFM06276.1 - 7.1e-09 34.8 21.6 0.13 12.4 0.0 7.8 8 1 1 9 9 9 4 Leucine Rich repeat LRR_5 PF13306.1 KFM06276.1 - 1.9e-08 34.1 0.7 2.9e-07 30.2 0.0 2.3 2 1 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_7 PF13504.1 KFM06276.1 - 0.0016 18.2 20.7 4.5 7.9 0.0 7.6 7 1 1 8 8 8 2 Leucine rich repeat LRR_9 PF14580.1 KFM06276.1 - 0.062 12.8 6.7 0.12 11.9 0.5 2.3 1 1 0 2 2 2 0 Leucine-rich repeat Cullin_binding PF03556.10 KFM06277.1 - 2.6e-33 114.6 1.3 4.6e-33 113.8 0.9 1.4 1 0 0 1 1 1 1 Cullin binding HCV_NS4a PF01006.15 KFM06278.1 - 0.043 13.3 0.0 0.12 11.9 0.0 1.8 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a OCIA PF07051.6 KFM06279.1 - 1.1e-31 108.4 0.0 2.1e-31 107.6 0.0 1.5 1 0 0 1 1 1 1 Ovarian carcinoma immunoreactive antigen (OCIA) DUF1183 PF06682.7 KFM06279.1 - 0.061 12.9 0.1 0.076 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF566 PF04484.7 KFM06279.1 - 1.1 8.7 7.9 1.4 8.3 5.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) zf-3CxxC PF13695.1 KFM06280.1 - 0.00014 22.0 8.3 0.00058 20.0 5.8 1.8 1 1 0 1 1 1 1 Zinc-binding domain DUF3392 PF11872.3 KFM06281.1 - 0.013 15.4 4.4 0.52 10.3 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3392) SLAIN PF15301.1 KFM06282.1 - 1e-135 452.6 37.8 1.2e-135 452.4 26.2 1.0 1 0 0 1 1 1 1 SLAIN motif-containing family LRR_8 PF13855.1 KFM06284.1 - 8.5e-44 147.1 23.9 3.4e-12 45.9 0.2 5.2 2 2 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 KFM06284.1 - 3.5e-24 83.9 28.3 5.5e-08 32.2 0.7 5.7 3 2 3 6 6 6 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFM06284.1 - 4.7e-22 78.0 0.0 2.9e-14 52.8 0.0 2.6 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_1 PF00560.28 KFM06284.1 - 8.2e-18 61.7 31.4 0.024 14.6 0.0 10.3 10 0 0 10 10 10 6 Leucine Rich Repeat I-set PF07679.11 KFM06284.1 - 5.1e-14 51.8 0.0 1e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.12 KFM06284.1 - 8.6e-08 32.0 0.1 2.1e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 KFM06284.1 - 1.2e-07 31.7 0.2 1.2e-07 31.7 0.1 1.8 2 0 0 2 2 1 1 Immunoglobulin domain LRR_7 PF13504.1 KFM06284.1 - 1.8e-06 27.2 30.0 1.5 9.3 0.0 9.2 9 0 0 9 9 9 4 Leucine rich repeat ig PF00047.20 KFM06284.1 - 1.5e-05 25.0 0.1 1.5e-05 25.0 0.1 2.4 2 0 0 2 2 2 1 Immunoglobulin domain LRR_9 PF14580.1 KFM06284.1 - 0.00015 21.3 5.1 0.0049 16.4 0.3 2.8 1 1 2 3 3 3 1 Leucine-rich repeat Ig_3 PF13927.1 KFM06284.1 - 0.00017 21.9 6.7 0.00046 20.6 0.3 3.7 2 2 0 2 2 2 1 Immunoglobulin domain Herpes_gE PF02480.11 KFM06284.1 - 0.0027 16.0 3.6 0.028 12.6 0.4 2.3 1 1 1 2 2 2 1 Alphaherpesvirus glycoprotein E gpUL132 PF11359.3 KFM06284.1 - 0.0072 15.6 1.8 0.0087 15.4 0.5 1.6 1 1 1 2 2 2 1 Glycoprotein UL132 LRR_6 PF13516.1 KFM06284.1 - 0.026 14.5 24.0 11 6.4 0.2 7.6 6 2 2 8 8 8 0 Leucine Rich repeat Syndecan PF01034.15 KFM06284.1 - 0.21 11.2 0.4 0.42 10.3 0.3 1.4 1 0 0 1 1 1 0 Syndecan domain API5 PF05918.6 KFM06286.1 - 3e-120 402.3 15.3 1.3e-119 400.2 10.6 2.0 1 1 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) HEAT_2 PF13646.1 KFM06286.1 - 2.5e-05 24.4 0.1 0.00021 21.4 0.1 2.3 2 0 0 2 2 2 1 HEAT repeats MMS19_N PF14500.1 KFM06286.1 - 0.011 14.9 2.9 0.061 12.5 2.0 2.1 1 1 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II DUF2435 PF10363.4 KFM06286.1 - 0.013 15.3 0.2 2.4 8.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) Dak2 PF02734.12 KFM06286.1 - 0.045 13.4 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 DAK2 domain InvH PF04741.7 KFM06286.1 - 0.064 13.1 0.7 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 InvH outer membrane lipoprotein TPR_11 PF13414.1 KFM06287.1 - 1.3e-22 79.1 13.9 6e-05 22.6 1.0 6.7 4 2 2 7 7 7 6 TPR repeat TPR_2 PF07719.12 KFM06287.1 - 5.1e-22 75.9 4.8 0.00076 19.2 0.0 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.23 KFM06287.1 - 1e-21 75.5 6.9 0.00026 20.4 0.1 8.5 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.1 KFM06287.1 - 1.9e-16 59.7 16.0 0.0042 16.9 0.3 6.8 3 3 4 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.1 KFM06287.1 - 3.5e-13 48.2 0.9 0.015 15.0 0.0 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFM06287.1 - 9.5e-12 43.7 5.8 0.044 13.5 0.0 7.1 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFM06287.1 - 2.6e-10 40.0 5.4 0.019 15.5 0.0 7.2 6 3 3 9 9 8 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFM06287.1 - 1.5e-06 28.7 6.2 0.036 14.7 0.6 4.7 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 KFM06287.1 - 3.5e-05 23.5 3.7 6 6.9 0.0 6.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFM06287.1 - 4.9e-05 23.1 12.8 4.1 7.8 0.0 7.8 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFM06287.1 - 0.00029 21.1 3.8 2.1 8.7 0.0 4.7 3 3 4 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 KFM06287.1 - 0.0022 17.8 0.8 0.36 10.7 0.0 3.8 5 0 0 5 5 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KFM06287.1 - 0.0044 16.8 0.2 1.3 8.9 0.1 2.9 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat ChAPs PF09295.5 KFM06287.1 - 0.009 14.8 0.5 0.009 14.8 0.3 2.7 3 2 1 4 4 4 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.1 KFM06287.1 - 0.013 15.8 1.0 79 4.0 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat 2OG-FeII_Oxy_2 PF13532.1 KFM06288.1 - 6.9e-32 110.8 0.0 8.3e-32 110.5 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KFM06288.1 - 7.2e-05 23.0 0.0 0.00011 22.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Aminotran_1_2 PF00155.16 KFM06289.1 - 1.2e-59 202.1 0.0 1.7e-59 201.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KFM06289.1 - 0.00048 19.3 0.0 0.00082 18.5 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Glyco_transf_64 PF09258.5 KFM06290.1 - 1.4e-95 319.1 0.2 2.1e-95 318.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Exostosin PF03016.10 KFM06290.1 - 1.9e-57 194.6 0.0 2.5e-57 194.2 0.0 1.1 1 0 0 1 1 1 1 Exostosin family DUF2387 PF09526.5 KFM06290.1 - 0.072 13.0 0.2 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) Fumble PF03630.9 KFM06290.1 - 0.14 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Fumble Homeobox PF00046.24 KFM06291.1 - 4.1e-25 87.1 6.0 7.4e-25 86.3 4.2 1.4 1 0 0 1 1 1 1 Homeobox domain OAR PF03826.12 KFM06291.1 - 2.3e-10 39.5 1.8 4.2e-10 38.7 1.3 1.4 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.6 KFM06291.1 - 0.0044 16.7 0.1 0.0091 15.6 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Tetraspannin PF00335.15 KFM06292.1 - 1.6e-46 158.3 10.9 3.9e-46 157.0 7.6 1.6 1 1 0 1 1 1 1 Tetraspanin family GATase_5 PF13507.1 KFM06292.1 - 0.0042 16.0 0.0 0.0057 15.5 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DUF3243 PF11588.3 KFM06292.1 - 0.033 14.1 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3243) Tetraspannin PF00335.15 KFM06293.1 - 2.7e-50 170.7 15.2 5.7e-50 169.6 10.6 1.5 1 1 0 1 1 1 1 Tetraspanin family SUR7 PF06687.7 KFM06293.1 - 0.78 9.2 15.4 0.02 14.4 3.5 2.6 3 0 0 3 3 3 0 SUR7/PalI family DUF872 PF05915.7 KFM06293.1 - 5 7.0 10.3 7 6.5 0.5 2.8 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF872) p53-inducible11 PF14936.1 KFM06294.1 - 4.6e-98 326.4 0.9 5.2e-98 326.2 0.6 1.0 1 0 0 1 1 1 1 Tumour protein p53-inducible protein 11 DUF3483 PF11982.3 KFM06294.1 - 0.024 13.9 0.2 0.036 13.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3483) SET PF00856.23 KFM06295.1 - 0.00023 21.4 0.2 0.002 18.4 0.0 2.6 2 1 0 2 2 2 1 SET domain C2 PF00168.25 KFM06296.1 - 1.4e-20 72.8 0.0 7.5e-13 48.1 0.0 2.3 2 0 0 2 2 2 2 C2 domain PI3K_C2 PF00792.19 KFM06296.1 - 0.0003 20.5 0.3 0.11 12.2 0.0 2.8 2 1 1 3 3 3 2 Phosphoinositide 3-kinase C2 Astacin PF01400.19 KFM06297.1 - 8.4e-62 207.9 0.0 1.5e-61 207.1 0.0 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) CUB PF00431.15 KFM06297.1 - 2.5e-30 104.7 0.1 9.1e-30 102.9 0.0 1.9 2 0 0 2 2 2 1 CUB domain SH3_9 PF14604.1 KFM06299.1 - 2.4e-09 36.6 0.0 4.6e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM06299.1 - 0.00015 21.0 0.0 0.00029 20.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain NodZ PF05830.6 KFM06299.1 - 0.046 12.2 0.5 0.12 10.9 0.0 1.7 2 0 0 2 2 2 0 Nodulation protein Z (NodZ) IncA PF04156.9 KFM06299.1 - 0.35 10.4 4.2 0.9 9.0 2.0 2.0 1 1 1 2 2 2 0 IncA protein C1q PF00386.16 KFM06301.1 - 1.4e-69 231.9 2.0 1.3e-37 128.6 0.1 2.1 2 0 0 2 2 2 2 C1q domain TOBE_2 PF08402.5 KFM06301.1 - 0.15 12.0 0.0 9.4 6.3 0.0 2.5 2 0 0 2 2 2 0 TOBE domain Complex1_30kDa PF00329.14 KFM06302.1 - 2.4e-33 114.4 0.1 3.2e-33 114.0 0.1 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit BTB PF00651.26 KFM06303.1 - 5.2e-26 90.8 2.2 9.5e-26 89.9 1.5 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.1 KFM06303.1 - 1.8e-17 62.7 3.3 6e-05 23.0 0.1 5.4 3 1 2 5 5 5 3 Kelch motif BACK PF07707.10 KFM06303.1 - 8.9e-10 38.3 0.7 9.7e-08 31.7 0.1 2.6 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_2 PF07646.10 KFM06303.1 - 3.3e-07 29.8 0.4 0.04 13.6 0.1 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 KFM06303.1 - 3.3e-07 29.7 6.4 0.058 12.9 0.0 5.1 6 0 0 6 6 6 3 Kelch motif Kelch_3 PF13415.1 KFM06303.1 - 7.2e-07 29.2 0.2 0.022 14.9 0.1 4.0 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.1 KFM06303.1 - 0.00031 20.6 2.0 0.061 13.2 0.0 4.2 5 0 0 5 5 5 1 Kelch motif Kelch_4 PF13418.1 KFM06303.1 - 0.0033 17.1 0.2 1 9.2 0.0 3.6 3 0 0 3 3 3 1 Galactose oxidase, central domain DSPc PF00782.15 KFM06304.1 - 1.8e-18 66.4 0.1 2e-18 66.2 0.1 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFM06304.1 - 5.2e-06 25.9 1.1 2.9e-05 23.5 0.2 1.8 1 1 1 2 2 2 1 Protein-tyrosine phosphatase DSPn PF14671.1 KFM06304.1 - 0.0026 17.7 0.0 0.0036 17.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half PTPlike_phytase PF14566.1 KFM06304.1 - 0.0077 16.2 0.1 0.014 15.4 0.0 1.6 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase2 PF03162.8 KFM06304.1 - 0.0099 15.2 0.1 0.01 15.2 0.1 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 KFM06304.1 - 0.088 13.0 0.1 0.3 11.3 0.0 1.8 1 1 1 2 2 2 0 Tyrosine phosphatase family RRM_1 PF00076.17 KFM06305.1 - 1.6e-51 171.7 0.0 4.2e-18 64.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM06305.1 - 1.5e-37 127.3 0.1 1.5e-11 44.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM06305.1 - 1.5e-29 101.6 0.5 1.5e-09 37.5 0.1 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 KFM06305.1 - 2.4e-06 27.4 0.0 0.4 10.7 0.0 3.5 3 0 0 3 3 3 3 RNA binding domain Nup35_RRM_2 PF14605.1 KFM06305.1 - 0.003 17.2 0.0 0.53 10.1 0.0 3.0 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 KFM06305.1 - 0.062 13.0 0.2 5.6 6.7 0.0 3.2 3 0 0 3 3 3 0 Limkain b1 Rapsyn_N PF10579.4 KFM06306.1 - 2.7e-44 148.8 0.2 3.8e-43 145.1 0.1 2.5 2 0 0 2 2 2 1 Rapsyn N-terminal myristoylation and linker region TPR_12 PF13424.1 KFM06306.1 - 2e-21 75.7 7.7 9.1e-08 31.9 0.0 5.2 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 KFM06306.1 - 4.7e-20 70.2 12.5 0.00015 21.2 0.0 7.1 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.1 KFM06306.1 - 3e-16 58.7 11.1 8.6e-06 25.3 0.4 5.4 3 2 2 5 5 5 4 TPR repeat TPR_2 PF07719.12 KFM06306.1 - 1.9e-15 55.4 12.2 0.007 16.2 0.1 6.7 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 KFM06306.1 - 9.3e-10 37.5 4.7 0.27 11.1 0.0 6.6 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFM06306.1 - 7.1e-09 34.8 11.7 0.071 12.9 0.0 6.6 7 0 0 7 7 7 3 Tetratricopeptide repeat zf-RING_2 PF13639.1 KFM06306.1 - 4.3e-07 29.6 3.9 4.3e-07 29.6 2.7 3.4 4 0 0 4 4 4 1 Ring finger domain TPR_19 PF14559.1 KFM06306.1 - 3.7e-06 27.1 0.6 5.2 7.4 0.0 4.6 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 KFM06306.1 - 1.7e-05 24.5 2.1 0.032 14.1 0.0 4.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFM06306.1 - 1.9e-05 24.8 2.3 1.7 9.4 0.0 5.6 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFM06306.1 - 4.5e-05 24.0 0.3 29 5.4 0.0 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat zf-RING_5 PF14634.1 KFM06306.1 - 9.4e-05 22.0 5.5 9.4e-05 22.0 3.8 3.7 4 0 0 4 4 3 1 zinc-RING finger domain DUF3856 PF12968.2 KFM06306.1 - 0.00036 20.3 0.9 2.1 8.1 0.0 3.7 2 1 1 3 3 3 2 Domain of Unknown Function (DUF3856) SNAP PF14938.1 KFM06306.1 - 0.00065 18.9 1.0 0.48 9.5 0.2 2.3 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_6 PF13174.1 KFM06306.1 - 0.0062 16.9 4.2 3.5 8.2 0.0 5.0 6 0 0 6 6 5 1 Tetratricopeptide repeat Apc5 PF12862.2 KFM06306.1 - 0.0084 15.9 1.3 1.6 8.6 0.6 3.6 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 5 Fis1_TPR_C PF14853.1 KFM06306.1 - 0.0085 15.9 3.1 0.66 9.8 0.0 4.1 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat RPN7 PF10602.4 KFM06306.1 - 0.0094 15.3 5.1 6.9 6.0 0.9 3.9 2 1 1 3 3 3 1 26S proteasome subunit RPN7 zf-rbx1 PF12678.2 KFM06306.1 - 0.024 14.7 5.5 0.1 12.6 3.8 2.1 1 0 0 1 1 1 0 RING-H2 zinc finger TPR_17 PF13431.1 KFM06306.1 - 0.49 10.7 8.7 2.7 8.4 0.3 5.0 4 1 0 4 4 4 0 Tetratricopeptide repeat AAA PF00004.24 KFM06307.1 - 5.9e-42 142.9 0.0 1.3e-41 141.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFM06307.1 - 2.8e-06 27.1 0.1 1.2e-05 25.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KFM06307.1 - 1.6e-05 24.9 0.1 0.00095 19.1 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 KFM06307.1 - 2.3e-05 23.5 0.1 9.9e-05 21.4 0.0 1.8 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KFM06307.1 - 0.00011 22.3 0.4 0.016 15.3 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 KFM06307.1 - 0.00015 21.7 0.0 0.00066 19.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KFM06307.1 - 0.0018 17.2 0.0 0.0034 16.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) PhoH PF02562.11 KFM06307.1 - 0.0021 17.3 0.0 0.0099 15.1 0.0 2.0 2 0 0 2 2 2 1 PhoH-like protein AAA_33 PF13671.1 KFM06307.1 - 0.0022 17.8 0.1 0.0044 16.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KFM06307.1 - 0.0044 16.2 0.1 0.013 14.6 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KFM06307.1 - 0.0048 16.3 0.0 0.0082 15.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 KFM06307.1 - 0.0054 16.4 0.2 0.012 15.3 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 KFM06307.1 - 0.0077 17.0 0.3 0.073 13.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KFM06307.1 - 0.025 13.7 0.1 0.044 12.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.1 KFM06307.1 - 0.03 13.7 1.0 0.26 10.6 0.1 2.2 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.21 KFM06307.1 - 0.033 13.6 0.0 0.26 10.7 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 KFM06307.1 - 0.034 13.7 1.0 0.062 12.8 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KFM06307.1 - 0.041 13.7 0.0 0.087 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KFM06307.1 - 0.046 12.8 0.3 0.14 11.2 0.0 2.0 3 0 0 3 3 3 0 KaiC TIP49 PF06068.8 KFM06307.1 - 0.071 11.8 0.1 0.16 10.6 0.0 1.6 2 0 0 2 2 2 0 TIP49 C-terminus NACHT PF05729.7 KFM06307.1 - 0.1 12.2 0.3 2.3 7.8 0.0 2.2 1 1 1 2 2 2 0 NACHT domain RNA_helicase PF00910.17 KFM06307.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Claudin_2 PF13903.1 KFM06308.1 - 6.3e-15 55.2 5.5 7e-15 55.1 3.8 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 KFM06308.1 - 0.016 14.8 8.3 0.022 14.3 5.8 1.3 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family DUF1056 PF06341.6 KFM06308.1 - 2 8.5 5.5 0.36 10.8 0.3 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1056) Zip PF02535.17 KFM06309.1 - 1.1e-55 188.9 2.5 1.7e-55 188.2 1.7 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter Ets PF00178.17 KFM06310.1 - 8.7e-30 102.6 4.4 1.3e-29 102.1 3.1 1.3 1 0 0 1 1 1 1 Ets-domain I-set PF07679.11 KFM06311.1 - 4.8e-105 343.6 14.6 6.8e-17 61.1 0.0 8.9 8 1 0 8 8 8 8 Immunoglobulin I-set domain fn3 PF00041.16 KFM06311.1 - 5.1e-40 135.4 0.0 5.6e-12 45.6 0.0 4.5 4 0 0 4 4 4 3 Fibronectin type III domain Ig_2 PF13895.1 KFM06311.1 - 5.4e-39 132.1 0.0 3.3e-08 33.5 0.0 8.4 7 1 1 8 8 8 8 Immunoglobulin domain V-set PF07686.12 KFM06311.1 - 1.9e-30 105.0 4.2 0.00086 19.1 0.1 9.4 7 2 1 8 8 8 7 Immunoglobulin V-set domain ig PF00047.20 KFM06311.1 - 5.1e-30 103.3 0.2 0.00012 22.0 0.0 8.1 8 1 0 8 8 8 6 Immunoglobulin domain Ig_3 PF13927.1 KFM06311.1 - 3e-16 59.6 0.0 0.00011 22.6 0.0 9.0 9 2 0 9 9 9 1 Immunoglobulin domain C2-set_2 PF08205.7 KFM06311.1 - 7.6e-10 38.5 0.2 0.079 12.8 0.0 6.5 5 1 1 6 6 6 1 CD80-like C2-set immunoglobulin domain C1-set PF07654.10 KFM06311.1 - 1.6e-05 24.8 5.8 13 5.8 0.0 6.9 6 1 1 7 7 7 1 Immunoglobulin C1-set domain Herpes_gI PF01688.12 KFM06311.1 - 0.01 14.9 0.0 43 3.1 0.0 4.6 5 0 0 5 5 5 0 Alphaherpesvirus glycoprotein I Herpes_gE PF02480.11 KFM06311.1 - 0.11 10.7 0.6 0.61 8.2 0.0 2.4 3 0 0 3 3 3 0 Alphaherpesvirus glycoprotein E DENN PF02141.16 KFM06312.1 - 1.6e-33 115.9 2.3 4.3e-33 114.5 1.6 1.7 1 1 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 KFM06312.1 - 3.2e-17 62.2 0.8 3.2e-17 62.2 0.5 2.2 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.14 KFM06312.1 - 2.2e-10 40.4 1.1 6.4e-10 38.9 0.1 2.4 2 0 0 2 2 2 1 dDENN domain Hormone_recep PF00104.25 KFM06313.1 - 3.2e-34 117.8 1.8 5.3e-34 117.1 1.2 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFM06313.1 - 7.3e-28 96.6 15.5 1.2e-27 95.8 10.7 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) His_Phos_2 PF00328.17 KFM06314.1 - 1.6e-38 132.9 0.1 1.9e-38 132.6 0.1 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) WD40 PF00400.27 KFM06315.1 - 8.7e-14 50.7 11.8 2.1e-05 24.1 0.0 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.3 KFM06315.1 - 0.0054 14.9 0.1 0.0076 14.4 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 ArfGap PF01412.13 KFM06316.1 - 1.2e-28 99.2 1.6 3.6e-28 97.6 1.1 1.8 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ldl_recept_b PF00058.12 KFM06318.1 - 9.9e-194 627.5 68.5 1.5e-13 50.8 0.2 20.6 20 0 0 20 20 20 20 Low-density lipoprotein receptor repeat class B Ldl_recept_a PF00057.13 KFM06318.1 - 7e-88 288.2 170.9 1.4e-12 47.3 11.2 9.2 8 0 0 8 8 8 8 Low-density lipoprotein receptor domain class A FXa_inhibition PF14670.1 KFM06318.1 - 1.7e-46 156.0 113.4 8.2e-12 45.0 4.9 8.7 8 0 0 8 8 8 6 Coagulation Factor Xa inhibitory site SGL PF08450.7 KFM06318.1 - 8e-31 107.2 28.6 3.6e-08 33.1 2.6 11.2 3 3 7 10 10 10 7 SMP-30/Gluconolaconase/LRE-like region cEGF PF12662.2 KFM06318.1 - 1.3e-12 47.0 35.7 1e-07 31.4 0.8 7.6 6 0 0 6 6 6 5 Complement Clr-like EGF-like NHL PF01436.16 KFM06318.1 - 0.00032 20.4 6.4 85 3.3 0.0 8.6 9 0 0 9 9 9 0 NHL repeat Str_synth PF03088.11 KFM06318.1 - 0.0028 17.6 0.0 25 4.9 0.0 5.9 6 0 0 6 6 6 0 Strictosidine synthase EGF PF00008.22 KFM06318.1 - 0.0048 16.8 2.1 0.0048 16.8 1.5 13.9 15 0 0 15 15 15 5 EGF-like domain SBBP PF06739.6 KFM06318.1 - 0.035 13.8 1.9 8.6 6.2 0.0 4.7 5 0 0 5 5 5 0 Beta-propeller repeat CLASP_N PF12348.3 KFM06319.1 - 1.1e-38 132.8 2.6 3.6e-11 42.8 0.0 5.5 5 0 0 5 5 5 5 CLASP N terminal HEAT_2 PF13646.1 KFM06319.1 - 4.5e-12 46.0 8.7 1 9.6 0.0 9.3 9 0 0 9 9 9 3 HEAT repeats HEAT PF02985.17 KFM06319.1 - 7.1e-11 41.2 15.1 0.025 14.6 0.0 11.1 14 0 0 14 14 14 3 HEAT repeat Vac14_Fab1_bd PF12755.2 KFM06319.1 - 2.3e-06 27.8 0.8 15 6.0 0.0 6.9 7 0 0 7 7 7 1 Vacuolar 14 Fab1-binding region ParcG PF10274.4 KFM06319.1 - 0.021 14.7 1.7 0.3 10.9 0.0 3.5 4 0 0 4 4 4 0 Parkin co-regulated protein DUF1247 PF06851.6 KFM06319.1 - 0.024 14.2 0.4 0.06 13.0 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1247) Cohesin_HEAT PF12765.2 KFM06319.1 - 0.063 13.2 4.0 17 5.4 0.0 4.5 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.1 KFM06319.1 - 1.8 9.1 12.5 1e+02 3.5 0.0 7.8 9 1 1 10 10 10 0 HEAT-like repeat Trypsin PF00089.21 KFM06320.1 - 6.2e-67 225.3 0.0 8.8e-67 224.9 0.0 1.2 1 0 0 1 1 1 1 Trypsin Kringle PF00051.13 KFM06320.1 - 5.4e-43 144.9 13.3 1.8e-22 79.1 3.1 2.6 2 0 0 2 2 2 2 Kringle domain Thrombin_light PF09396.5 KFM06320.1 - 2.5e-26 91.0 2.2 5.7e-26 89.8 1.6 1.6 1 0 0 1 1 1 1 Thrombin light chain Gla PF00594.15 KFM06320.1 - 4.6e-16 58.2 5.6 9.9e-16 57.1 3.9 1.6 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain DUF1986 PF09342.6 KFM06320.1 - 4.8e-06 26.0 0.1 9.1e-06 25.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) RhoGAP PF00620.22 KFM06321.1 - 3.3e-45 153.4 0.3 6.8e-45 152.3 0.2 1.5 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.1 KFM06321.1 - 1e-41 142.2 5.6 1.6e-40 138.4 1.2 2.3 2 0 0 2 2 2 2 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 KFM06321.1 - 9.6e-10 38.1 0.3 1.9e-09 37.1 0.2 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain ATG13 PF10033.4 KFM06322.1 - 9.2e-32 110.3 0.0 2.2e-31 109.0 0.0 1.6 1 1 0 1 1 1 1 Autophagy-related protein 13 DDE_Tnp_4 PF13359.1 KFM06323.1 - 3e-36 124.4 0.0 4.2e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 KFM06323.1 - 1.1e-06 28.2 0.0 5.6e-05 22.6 0.0 2.2 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.16 KFM06323.1 - 0.0035 16.9 0.0 1.7 8.1 0.1 2.1 1 1 1 2 2 2 2 Transposase DDE domain WD40 PF00400.27 KFM06324.1 - 5.3e-14 51.4 2.0 2.7e-09 36.5 0.7 5.2 6 0 0 6 6 6 2 WD domain, G-beta repeat eIF2A PF08662.6 KFM06324.1 - 0.038 13.6 0.0 0.092 12.4 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A CAP_N PF01213.14 KFM06324.1 - 7.7 5.7 11.6 1.8 7.7 5.5 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal 7tm_1 PF00001.16 KFM06325.1 - 1.5e-82 276.6 6.4 2.4e-82 275.9 4.4 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM06325.1 - 2.7e-06 26.7 15.6 7.3e-06 25.3 4.4 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx PgaD PF13994.1 KFM06325.1 - 0.69 9.4 6.1 0.088 12.2 0.2 2.4 3 0 0 3 3 3 0 PgaD-like protein PTN_MK_C PF01091.13 KFM06326.1 - 1.7e-29 101.6 7.8 1.7e-29 101.6 5.4 2.8 2 1 1 3 3 3 1 PTN/MK heparin-binding protein family, C-terminal domain PTN_MK_N PF05196.8 KFM06326.1 - 1.1e-28 98.8 18.7 1.1e-28 98.8 13.0 2.6 2 1 1 3 3 3 1 PTN/MK heparin-binding protein family, N-terminal domain DAGK_acc PF00609.14 KFM06327.1 - 2.1e-47 161.2 0.0 3.7e-47 160.4 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 KFM06327.1 - 1.8e-33 114.7 0.0 5.5e-33 113.1 0.0 1.9 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Ank_2 PF12796.2 KFM06327.1 - 1.1e-14 54.5 0.1 1.5e-07 31.6 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) C1_1 PF00130.17 KFM06327.1 - 3.5e-12 45.8 26.0 9.5e-10 38.0 9.7 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Ank_5 PF13857.1 KFM06327.1 - 3.9e-11 42.8 0.0 2.4e-05 24.3 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM06327.1 - 1.3e-10 40.4 0.0 2.4e-05 24.1 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KFM06327.1 - 3.2e-09 37.0 0.0 0.00021 21.6 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 KFM06327.1 - 8.1e-09 34.8 0.0 0.00085 19.0 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat bZIP_1 PF00170.16 KFM06329.1 - 2.9e-15 55.9 13.9 6.1e-15 54.9 9.6 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFM06329.1 - 1.5e-09 37.4 9.1 1.5e-09 37.4 6.3 2.2 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_Maf PF03131.12 KFM06329.1 - 2.5e-05 24.4 10.1 5.1e-05 23.4 7.0 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor TPR_MLP1_2 PF07926.7 KFM06329.1 - 0.068 12.9 10.1 0.12 12.1 7.0 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein APG6 PF04111.7 KFM06329.1 - 0.17 10.9 6.7 0.27 10.2 4.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3552 PF12072.3 KFM06329.1 - 0.26 10.4 9.3 0.4 9.8 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) ADIP PF11559.3 KFM06329.1 - 0.26 11.1 11.7 0.46 10.3 8.1 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding HI0933_like PF03486.9 KFM06329.1 - 0.4 9.0 2.3 0.96 7.8 0.7 1.9 2 0 0 2 2 2 0 HI0933-like protein PHD PF00628.24 KFM06330.1 - 1e-12 47.5 6.5 2.2e-12 46.4 4.5 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KFM06330.1 - 0.001 18.3 0.8 0.0033 16.7 0.6 1.9 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 KFM06330.1 - 0.0012 18.4 3.3 0.017 14.8 1.5 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 C1_1 PF00130.17 KFM06330.1 - 0.0013 18.3 1.1 0.0013 18.3 0.8 2.0 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) AT_hook PF02178.14 KFM06330.1 - 0.0069 15.9 2.0 0.02 14.5 1.4 1.8 1 0 0 1 1 1 1 AT hook motif zf-HC5HC2H PF13771.1 KFM06330.1 - 0.021 14.9 2.4 0.022 14.9 0.1 2.1 2 0 0 2 2 2 0 PHD-like zinc-binding domain ADK_lid PF05191.9 KFM06330.1 - 0.037 13.6 2.0 0.13 11.9 1.4 1.9 1 0 0 1 1 1 0 Adenylate kinase, active site lid ENT PF03735.9 KFM06330.1 - 0.11 12.1 2.8 7.1 6.4 0.3 2.7 1 1 1 2 2 2 0 ENT domain Seryl_tRNA_N PF02403.17 KFM06330.1 - 0.12 12.3 20.2 0.63 10.0 3.2 2.9 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain zf-RING_2 PF13639.1 KFM06330.1 - 0.79 9.6 7.5 1.6 8.6 5.2 1.5 1 0 0 1 1 1 0 Ring finger domain C1_3 PF07649.7 KFM06330.1 - 1.5 8.8 4.8 2.8 8.0 3.4 1.4 1 0 0 1 1 1 0 C1-like domain Erp_C PF06780.6 KFM06330.1 - 5 6.9 11.7 0.23 11.3 2.8 2.3 2 0 0 2 2 2 0 Erp protein C-terminus APG6 PF04111.7 KFM06330.1 - 5.9 5.8 25.0 3.7 6.5 4.0 2.4 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF1664 PF07889.7 KFM06330.1 - 9.3 6.0 15.1 1.4 8.6 2.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Pex16 PF08610.5 KFM06332.1 - 3.7e-82 276.0 4.0 4.2e-82 275.8 2.8 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) DUF29 PF01724.11 KFM06332.1 - 1.1 9.0 5.6 0.54 10.0 0.2 2.7 1 1 2 3 3 3 0 Domain of unknown function DUF29 PID PF00640.18 KFM06334.1 - 5.6e-33 113.8 0.3 9.4e-33 113.1 0.2 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SH3_9 PF14604.1 KFM06334.1 - 7.3e-12 44.6 0.1 1.4e-11 43.7 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM06334.1 - 1.2e-05 24.6 0.0 2.1e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain PID_2 PF14719.1 KFM06334.1 - 0.0024 17.5 0.1 0.0041 16.7 0.1 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.8 KFM06334.1 - 0.15 12.0 0.7 0.38 10.6 0.1 2.0 2 1 0 2 2 2 0 Phosphotyrosine-binding domain TPT PF03151.11 KFM06335.1 - 1.2e-15 57.4 19.1 1.1e-11 44.5 6.0 2.4 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 KFM06335.1 - 2.9e-10 39.5 12.1 3.9e-10 39.1 8.4 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 KFM06335.1 - 1.2e-06 28.5 19.6 7.2e-05 22.8 3.0 2.7 2 2 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 KFM06335.1 - 0.025 14.7 2.9 0.025 14.7 2.0 3.8 3 2 1 4 4 4 0 Multidrug resistance efflux transporter Vma12 PF11712.3 KFM06335.1 - 3.9 7.1 4.7 0.94 9.1 0.8 1.8 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Sulfotransfer_1 PF00685.22 KFM06336.1 - 1e-58 198.7 0.0 1.2e-58 198.4 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 KFM06336.1 - 2.8e-05 25.1 0.2 7.4e-05 23.7 0.2 1.7 1 1 0 1 1 1 1 Sulfotransferase family Sulphotransf PF09037.5 KFM06336.1 - 0.062 12.7 0.0 3.5 7.0 0.0 2.4 2 0 0 2 2 2 0 Stf0 sulphotransferase UPF0444 PF15475.1 KFM06337.1 - 5.2e-45 151.4 13.3 5.8e-45 151.2 9.2 1.0 1 0 0 1 1 1 1 Transmembrane protein C12orf23, UPF0444 CUB PF00431.15 KFM06338.1 - 3.8e-64 213.6 0.2 6e-32 109.9 0.0 2.7 3 0 0 3 3 3 2 CUB domain Astacin PF01400.19 KFM06338.1 - 6.7e-59 198.4 0.0 1e-58 197.8 0.0 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) CUB_2 PF02408.15 KFM06338.1 - 0.003 17.0 3.0 0.086 12.3 0.1 2.7 2 0 0 2 2 2 2 CUB-like domain ABC_transp_aux PF09822.4 KFM06339.1 - 0.028 13.8 1.6 0.044 13.2 1.1 1.2 1 0 0 1 1 1 0 ABC-type uncharacterized transport system Cytochrome_CBB3 PF13442.1 KFM06339.1 - 0.1 12.7 0.2 0.1 12.7 0.1 2.1 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III FYVE PF01363.16 KFM06339.1 - 1.5 8.7 27.0 0.05 13.5 8.8 2.5 2 0 0 2 2 2 0 FYVE zinc finger DUF3135 PF11333.3 KFM06339.1 - 4.9 7.3 7.5 12 6.0 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3135) Kunitz_BPTI PF00014.18 KFM06340.1 - 1.5e-32 111.5 24.0 7.3e-19 67.7 6.4 3.6 4 0 0 4 4 3 2 Kunitz/Bovine pancreatic trypsin inhibitor domain MANEC PF07502.9 KFM06340.1 - 3.6e-27 94.2 1.0 3.6e-27 94.2 0.7 2.7 4 0 0 4 4 2 1 MANEC domain Ldl_recept_a PF00057.13 KFM06340.1 - 6.8e-09 35.4 13.2 3.4e-08 33.2 9.1 2.3 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A DUF912 PF06024.7 KFM06340.1 - 0.00018 21.5 0.2 0.00045 20.2 0.0 1.7 2 0 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) REJ PF02010.10 KFM06340.1 - 0.01 14.1 0.2 0.042 12.1 0.1 1.9 1 1 0 1 1 1 0 REJ domain EphA2_TM PF14575.1 KFM06340.1 - 0.035 14.4 0.6 0.097 13.0 0.0 2.0 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain Chordopox_A13L PF05961.6 KFM06340.1 - 0.039 13.8 0.1 0.09 12.7 0.0 1.6 1 0 0 1 1 1 0 Chordopoxvirus A13L protein IncA PF04156.9 KFM06340.1 - 0.075 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 IncA protein DUF3377 PF11857.3 KFM06340.1 - 0.086 12.4 0.1 0.26 10.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) PKD PF00801.15 KFM06340.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 PKD domain SKG6 PF08693.5 KFM06340.1 - 1.4 8.3 4.2 3.8 6.9 2.9 1.7 1 1 0 1 1 1 0 Transmembrane alpha-helix domain Ras PF00071.17 KFM06341.1 - 3.2e-32 111.1 0.0 3.9e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM06341.1 - 1.7e-09 38.1 0.0 3.1e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM06341.1 - 0.077 12.2 0.0 0.12 11.5 0.0 1.3 1 1 0 1 1 1 0 ADP-ribosylation factor family Pep3_Vps18 PF05131.9 KFM06342.1 - 1.1e-45 154.7 0.4 2e-44 150.6 0.0 2.6 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 KFM06342.1 - 1.5e-11 44.0 18.5 3.2e-09 36.5 2.9 3.0 2 1 0 2 2 2 2 Region in Clathrin and VPS Vps39_2 PF10367.4 KFM06342.1 - 0.00061 19.9 0.4 0.0026 17.8 0.2 2.1 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.1 KFM06342.1 - 0.00067 19.4 0.3 0.00067 19.4 0.2 2.4 3 0 0 3 3 2 1 Ring finger domain Lact-deh-memb PF09330.6 KFM06342.1 - 0.0037 16.6 0.9 0.19 11.0 0.1 2.7 2 0 0 2 2 2 1 D-lactate dehydrogenase, membrane binding zf-RING_5 PF14634.1 KFM06342.1 - 0.0062 16.2 0.3 0.024 14.3 0.2 2.0 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KFM06342.1 - 0.017 15.1 0.1 0.059 13.4 0.1 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger DUF1664 PF07889.7 KFM06342.1 - 0.028 14.2 1.3 0.06 13.1 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) zf-Apc11 PF12861.2 KFM06342.1 - 0.032 14.0 0.2 0.1 12.4 0.2 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Fib_alpha PF08702.5 KFM06342.1 - 0.058 13.5 1.6 0.72 9.9 0.1 2.8 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family zf-C3HC4_2 PF13923.1 KFM06342.1 - 0.13 12.3 5.1 0.043 13.8 0.7 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) EGF PF00008.22 KFM06343.1 - 4.9e-38 128.6 130.9 2.3e-09 37.0 6.8 9.4 8 1 0 8 8 8 7 EGF-like domain MNNL PF07657.8 KFM06343.1 - 1e-22 79.8 0.5 1e-22 79.8 0.3 3.9 4 1 1 5 5 5 1 N terminus of Notch ligand hEGF PF12661.2 KFM06343.1 - 2.6e-17 61.6 83.0 0.0031 17.4 2.4 9.3 8 0 0 8 8 8 8 Human growth factor-like EGF EGF_2 PF07974.8 KFM06343.1 - 1.3e-13 50.7 145.9 0.017 15.2 7.4 8.9 8 0 0 8 8 8 8 EGF-like domain cEGF PF12662.2 KFM06343.1 - 1.8e-06 27.4 83.4 0.011 15.3 6.8 8.8 8 1 0 8 8 8 5 Complement Clr-like EGF-like Laminin_EGF PF00053.19 KFM06343.1 - 6.3e-05 22.8 106.0 0.035 14.0 7.1 8.8 2 2 6 8 8 8 4 Laminin EGF-like (Domains III and V) EGF_CA PF07645.10 KFM06343.1 - 7.3e-05 22.6 7.6 7.3e-05 22.6 5.3 9.3 4 2 4 8 8 8 3 Calcium-binding EGF domain EGF_3 PF12947.2 KFM06343.1 - 0.0002 21.2 6.9 0.0002 21.2 4.8 9.2 7 2 1 8 8 8 5 EGF domain DUF4381 PF14316.1 KFM06343.1 - 0.035 14.2 0.0 0.06 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) SNF2_N PF00176.18 KFM06344.1 - 2.7e-71 239.8 5.7 2.7e-71 239.8 4.0 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.1 KFM06344.1 - 8.4e-51 171.6 20.8 8.4e-51 171.6 14.4 3.9 3 0 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.26 KFM06344.1 - 5.5e-14 51.7 0.0 1.6e-13 50.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain EF-hand_6 PF13405.1 KFM06345.1 - 6.9e-17 59.7 0.9 4.2e-07 29.3 0.2 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.27 KFM06345.1 - 4.7e-16 56.7 2.3 4.7e-06 25.5 0.2 3.5 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 KFM06345.1 - 4.1e-15 55.6 2.6 2.1e-10 40.5 0.5 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KFM06345.1 - 7.2e-08 31.9 4.9 2.2e-05 23.9 0.3 3.8 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 KFM06345.1 - 1.8e-07 30.2 5.2 0.01 15.1 0.2 3.4 3 0 0 3 3 3 3 EF hand SPARC_Ca_bdg PF10591.4 KFM06345.1 - 1.8e-05 24.7 0.0 0.00054 19.9 0.0 2.2 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region RST PF12174.3 KFM06345.1 - 0.00073 19.2 0.1 0.0026 17.5 0.0 2.0 2 0 0 2 2 2 1 RCD1-SRO-TAF4 (RST) plant domain EF-hand_4 PF12763.2 KFM06345.1 - 0.051 13.3 1.3 1.9 8.2 0.1 2.4 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KFM06345.1 - 0.12 12.3 0.1 3.9 7.4 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain LMBR1 PF04791.11 KFM06346.1 - 0.074 11.6 1.0 0.089 11.3 0.1 1.7 1 1 1 2 2 2 0 LMBR1-like membrane protein TRAUB PF08164.7 KFM06346.1 - 0.26 11.4 0.1 0.26 11.4 0.1 4.0 3 2 2 5 5 5 0 Apoptosis-antagonizing transcription factor, C-terminal CIA30 PF08547.7 KFM06347.1 - 4.5e-45 153.3 0.2 7e-45 152.6 0.0 1.4 2 0 0 2 2 2 1 Complex I intermediate-associated protein 30 (CIA30) Plus-3 PF03126.13 KFM06348.1 - 2e-37 127.5 0.0 2e-37 127.5 0.0 2.3 3 0 0 3 3 3 1 Plus-3 domain Sulfotransfer_2 PF03567.9 KFM06349.1 - 5.3e-44 150.8 2.4 6.2e-44 150.5 1.6 1.1 1 0 0 1 1 1 1 Sulfotransferase family Complex1_LYR PF05347.10 KFM06349.1 - 0.034 13.9 0.1 0.1 12.4 0.1 1.8 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Pkip-1 PF06878.6 KFM06349.1 - 0.04 13.8 0.4 0.04 13.8 0.3 1.6 2 1 0 2 2 2 0 Pkip-1 protein IPK PF03770.11 KFM06350.1 - 2e-42 145.0 0.0 4.8e-42 143.8 0.0 1.6 1 1 0 1 1 1 1 Inositol polyphosphate kinase Pkinase_Tyr PF07714.12 KFM06351.1 - 2.5e-89 298.7 0.0 3.3e-89 298.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM06351.1 - 1.3e-36 126.0 0.0 1.9e-36 125.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Gly_rich PF12810.2 KFM06351.1 - 3e-20 72.8 24.4 4.8e-20 72.2 16.9 1.2 1 0 0 1 1 1 1 Glycine rich protein Kinase-like PF14531.1 KFM06351.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RPAP1_C PF08620.5 KFM06352.1 - 5e-26 90.3 2.6 6.9e-26 89.8 0.3 2.3 2 0 0 2 2 2 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 KFM06352.1 - 5.4e-17 61.1 4.6 1.5e-16 59.6 3.2 1.8 1 0 0 1 1 1 1 RPAP1-like, N-terminal TMEM151 PF14857.1 KFM06353.1 - 4e-204 678.0 14.0 4.4e-204 677.8 9.7 1.0 1 0 0 1 1 1 1 TMEM151 family Pkinase_Tyr PF07714.12 KFM06354.1 - 1.8e-87 292.6 0.0 2.4e-87 292.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM06354.1 - 2.2e-41 141.7 0.0 3e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain I-set PF07679.11 KFM06354.1 - 8.5e-18 63.9 0.3 3.5e-14 52.4 0.1 2.7 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM06354.1 - 1.6e-15 56.9 0.0 3.5e-11 43.0 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain fn3 PF00041.16 KFM06354.1 - 2.4e-15 56.3 0.3 3.7e-09 36.5 0.2 2.5 2 0 0 2 2 2 2 Fibronectin type III domain Ig_3 PF13927.1 KFM06354.1 - 9.5e-10 38.8 1.7 0.0077 16.7 0.1 4.1 3 1 0 3 3 3 2 Immunoglobulin domain V-set PF07686.12 KFM06354.1 - 2.3e-06 27.4 0.0 1.5e-05 24.8 0.0 2.3 1 1 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 KFM06354.1 - 3.1e-06 27.2 0.5 2.1e-05 24.5 0.0 2.6 2 1 1 3 3 3 1 Immunoglobulin domain DUF4229 PF14012.1 KFM06354.1 - 0.035 14.0 0.2 0.069 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) Kinase-like PF14531.1 KFM06354.1 - 0.042 12.8 0.0 0.069 12.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RuBisCO_large_N PF02788.11 KFM06355.1 - 1.9 8.2 6.0 1.7 8.3 3.5 1.4 1 1 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain WD40 PF00400.27 KFM06357.1 - 3.8e-49 162.8 26.0 3e-08 33.2 0.3 11.8 11 0 0 11 11 11 11 WD domain, G-beta repeat Hira PF07569.6 KFM06357.1 - 0.063 12.4 0.0 0.43 9.7 0.0 2.4 2 0 0 2 2 2 0 TUP1-like enhancer of split Cupin_8 PF13621.1 KFM06359.1 - 4.6e-55 186.8 0.0 8.3e-55 185.9 0.0 1.4 1 0 0 1 1 1 1 Cupin-like domain PLA2_B PF01735.13 KFM06359.1 - 1.1e-25 89.8 0.0 3.4e-25 88.1 0.0 1.8 3 0 0 3 3 3 1 Lysophospholipase catalytic domain C2 PF00168.25 KFM06359.1 - 1.2e-19 69.9 0.1 2.7e-19 68.7 0.1 1.6 1 0 0 1 1 1 1 C2 domain EF-hand_4 PF12763.2 KFM06361.1 - 5.8e-16 58.1 0.0 2.8e-15 55.9 0.0 2.1 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Dynamin_N PF00350.18 KFM06361.1 - 4.6e-11 42.8 0.0 2.3e-10 40.5 0.0 2.1 2 1 0 2 2 2 1 Dynamin family EF-hand_1 PF00036.27 KFM06361.1 - 0.00088 18.4 0.6 0.0033 16.6 0.1 2.3 2 0 0 2 2 2 1 EF hand MMR_HSR1 PF01926.18 KFM06361.1 - 0.001 19.0 0.0 0.0032 17.4 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase UPF0278 PF08745.6 KFM06361.1 - 0.021 14.0 0.2 0.049 12.8 0.0 1.6 2 0 0 2 2 2 0 UPF0278 family EF-hand_7 PF13499.1 KFM06361.1 - 0.041 14.0 0.0 0.16 12.1 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain pair GTP_EFTU PF00009.22 KFM06361.1 - 0.16 11.3 0.5 0.38 10.1 0.3 1.8 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain EF-hand_8 PF13833.1 KFM06361.1 - 0.17 11.4 0.9 1.4 8.5 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain pair PLA2_B PF01735.13 KFM06362.1 - 1.8e-27 95.6 0.0 2.4e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain PLA2_B PF01735.13 KFM06363.1 - 1.5e-36 125.5 0.0 5.9e-33 113.7 0.0 2.3 2 0 0 2 2 2 2 Lysophospholipase catalytic domain C2 PF00168.25 KFM06363.1 - 1.2e-18 66.6 0.6 1.2e-18 66.6 0.4 1.9 2 0 0 2 2 2 1 C2 domain PLA2_B PF01735.13 KFM06364.1 - 2.8e-26 91.7 0.0 7.8e-26 90.2 0.0 1.8 1 1 0 1 1 1 1 Lysophospholipase catalytic domain C2 PF00168.25 KFM06364.1 - 4.9e-15 55.1 0.8 1.4e-14 53.7 0.5 1.8 1 0 0 1 1 1 1 C2 domain PLA2_B PF01735.13 KFM06365.1 - 1.1e-25 89.7 0.0 1.4e-25 89.4 0.0 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain DUF1133 PF06576.6 KFM06365.1 - 0.085 12.0 0.1 0.13 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1133) C2 PF00168.25 KFM06366.1 - 2.3e-16 59.3 2.1 2.2e-15 56.2 0.2 2.0 1 1 1 2 2 2 2 C2 domain PLA2_B PF01735.13 KFM06367.1 - 6.1e-29 100.5 0.0 8.1e-29 100.1 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain DUF3986 PF13143.1 KFM06367.1 - 0.058 13.8 0.3 0.12 12.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3986) C2 PF00168.25 KFM06368.1 - 8.4e-21 73.6 0.1 1.1e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 C2 domain QRPTase_N PF02749.11 KFM06368.1 - 0.088 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain PLA2_B PF01735.13 KFM06369.1 - 3.3e-40 137.6 0.4 9.8e-34 116.3 0.0 3.0 2 1 1 3 3 3 3 Lysophospholipase catalytic domain C2 PF00168.25 KFM06369.1 - 4e-16 58.6 0.2 1.3e-15 57.0 0.1 1.9 1 0 0 1 1 1 1 C2 domain CNH PF00780.17 KFM06370.1 - 1e-48 166.1 0.1 2.2e-48 165.0 0.1 1.6 1 0 0 1 1 1 1 CNH domain Vps39_1 PF10366.4 KFM06370.1 - 2e-32 111.3 2.8 2e-32 111.3 2.0 3.2 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 KFM06370.1 - 9.4e-32 109.4 5.0 9.4e-32 109.4 3.5 2.7 3 1 1 4 4 4 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.15 KFM06370.1 - 3.7e-12 46.0 11.3 1.1e-06 28.2 0.7 4.1 3 1 0 3 3 3 2 Region in Clathrin and VPS zf-FCS PF06467.9 KFM06370.1 - 0.0074 15.9 0.2 0.019 14.5 0.2 1.8 1 0 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif TPR_12 PF13424.1 KFM06370.1 - 0.073 13.0 0.6 86 3.1 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Lgl_C PF08596.5 KFM06370.1 - 0.081 11.3 0.0 0.13 10.6 0.0 1.2 1 0 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal Apc3 PF12895.2 KFM06370.1 - 0.24 11.5 3.1 1.2 9.2 0.2 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Glyco_hydro_31 PF01055.21 KFM06371.1 - 1.1e-162 541.9 2.1 1.3e-162 541.6 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KFM06371.1 - 9.2e-17 60.6 0.0 2.7e-16 59.1 0.0 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like Peptidase_C2 PF00648.16 KFM06372.1 - 3.1e-149 495.8 0.9 6.8e-148 491.4 0.6 2.2 1 1 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 KFM06372.1 - 1.9e-60 202.7 0.0 4.8e-60 201.4 0.0 1.7 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_1 PF00036.27 KFM06372.1 - 4.4e-18 63.1 11.8 5e-07 28.5 0.1 6.0 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.1 KFM06372.1 - 2.8e-17 60.9 6.8 0.0011 18.6 0.0 5.6 6 0 0 6 6 6 4 EF-hand domain EF-hand_8 PF13833.1 KFM06372.1 - 4.5e-13 48.6 11.4 1.5e-09 37.3 0.5 4.5 4 1 0 4 4 4 2 EF-hand domain pair EF-hand_7 PF13499.1 KFM06372.1 - 9.4e-13 48.1 11.5 1.9e-05 24.6 0.3 4.3 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 KFM06372.1 - 5.4e-12 44.4 7.3 0.00025 20.2 0.0 4.7 5 0 0 5 5 5 3 EF hand EF-hand_4 PF12763.2 KFM06372.1 - 0.018 14.7 3.4 0.51 10.0 0.2 2.9 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand WD40 PF00400.27 KFM06373.1 - 2.2e-31 106.5 4.8 1.6e-05 24.5 0.1 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat PQQ PF01011.16 KFM06373.1 - 0.26 10.8 0.9 2.1e+02 1.7 0.0 4.7 5 0 0 5 5 5 0 PQQ enzyme repeat PQQ_3 PF13570.1 KFM06373.1 - 0.36 11.1 2.5 1.7e+02 2.6 0.0 4.8 6 0 0 6 6 6 0 PQQ-like domain SNARE PF05739.14 KFM06374.1 - 1.1e-15 57.0 13.1 3.1e-10 39.5 2.6 2.4 2 0 0 2 2 2 2 SNARE domain SNAP-25 PF00835.14 KFM06374.1 - 3.6e-13 50.0 0.9 6.1e-13 49.3 0.6 1.4 1 0 0 1 1 1 1 SNAP-25 family V-SNARE_C PF12352.3 KFM06374.1 - 0.00034 20.6 5.2 0.02 14.9 0.8 2.5 2 1 1 3 3 3 2 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KFM06374.1 - 0.08 12.6 2.1 0.082 12.6 0.5 1.7 2 0 0 2 2 2 0 Sec20 NPV_P10 PF05531.7 KFM06374.1 - 0.35 11.1 2.7 10 6.4 0.1 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 KFM06374.1 - 1 9.1 5.7 0.32 10.8 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) LRR_4 PF12799.2 KFM06375.1 - 2.9e-28 96.9 27.4 5.9e-09 35.3 2.1 5.1 5 0 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM06375.1 - 1.5e-19 69.4 21.9 1.6e-11 43.7 1.8 3.6 2 1 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 KFM06375.1 - 8.6e-17 58.5 22.2 0.035 14.1 0.2 8.0 8 0 0 8 8 8 6 Leucine Rich Repeat LRR_7 PF13504.1 KFM06375.1 - 3e-10 38.5 24.3 0.3 11.4 0.0 7.9 7 0 0 7 7 7 4 Leucine rich repeat LRR_6 PF13516.1 KFM06375.1 - 1.1e-08 34.2 23.2 0.44 10.7 0.6 7.6 6 1 1 7 7 7 5 Leucine Rich repeat LRR_9 PF14580.1 KFM06375.1 - 1.6e-05 24.5 7.7 0.0029 17.2 1.1 2.2 1 1 1 2 2 2 2 Leucine-rich repeat HAUS2 PF15003.1 KFM06376.1 - 3.5e-46 157.4 6.7 4.1e-46 157.2 4.6 1.0 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 2 Vac_Fusion PF02346.11 KFM06376.1 - 0.53 9.7 5.5 1.4 8.3 0.0 2.9 3 0 0 3 3 3 0 Chordopoxvirus fusion protein Kinesin PF00225.18 KFM06377.1 - 1.1e-104 349.7 0.1 1.1e-104 349.7 0.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain FHA PF00498.21 KFM06377.1 - 1.1e-07 31.8 1.6 3.6e-07 30.2 0.2 2.6 2 0 0 2 2 2 1 FHA domain Codanin-1_C PF15296.1 KFM06378.1 - 6.9e-45 151.8 0.1 1.7e-44 150.5 0.1 1.7 1 0 0 1 1 1 1 Codanin-1 C-terminus CTP_transf_1 PF01148.15 KFM06378.1 - 0.36 10.4 0.4 0.57 9.7 0.3 1.2 1 0 0 1 1 1 0 Cytidylyltransferase family Pkinase PF00069.20 KFM06379.1 - 2.5e-32 112.0 0.0 4.7e-32 111.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM06379.1 - 2.8e-18 65.9 0.0 4.7e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFM06379.1 - 0.084 12.5 0.0 7.4 6.2 0.0 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family Tetraspannin PF00335.15 KFM06380.1 - 4.6e-49 166.6 17.0 1.1e-48 165.4 11.8 1.5 1 1 0 1 1 1 1 Tetraspanin family ArfGap PF01412.13 KFM06380.1 - 0.11 12.2 2.8 0.31 10.8 1.9 1.7 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf ClpS PF02617.12 KFM06381.1 - 1.2e-19 69.8 0.2 3e-19 68.5 0.1 1.8 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-UBR PF02207.15 KFM06381.1 - 5.1e-15 54.9 17.4 5.1e-15 54.9 12.1 3.3 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) Metallophos_2 PF12850.2 KFM06382.1 - 0.005 16.6 0.0 0.015 15.1 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ADH_zinc_N PF00107.21 KFM06383.1 - 1.2e-17 63.6 0.0 2.2e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFM06383.1 - 1.3e-12 48.7 0.0 1.7e-11 45.1 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Orthopox_F14 PF06076.7 KFM06383.1 - 0.0041 17.1 0.0 0.0078 16.2 0.0 1.4 1 0 0 1 1 1 1 Orthopoxvirus F14 protein ELM2 PF01448.19 KFM06384.1 - 1.8e-12 47.7 1.5 3.6e-12 46.7 0.0 2.5 2 0 0 2 2 2 1 ELM2 domain Myb_DNA-binding PF00249.26 KFM06384.1 - 0.0036 17.3 0.0 0.0091 16.0 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain LRR_4 PF12799.2 KFM06385.1 - 2.2e-16 59.0 11.5 8.5e-07 28.4 0.0 3.8 2 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM06385.1 - 2.5e-08 33.5 9.4 0.00061 19.4 0.0 3.4 3 1 1 4 4 4 3 Leucine rich repeat LRR_9 PF14580.1 KFM06385.1 - 2.5e-07 30.4 1.5 1.2e-06 28.2 0.7 1.9 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.28 KFM06385.1 - 1.8e-05 24.1 10.9 1.8 8.8 0.5 5.1 4 1 0 4 4 4 3 Leucine Rich Repeat LRR_6 PF13516.1 KFM06385.1 - 0.00038 20.2 5.7 1.1 9.5 0.5 4.5 4 1 1 5 5 5 1 Leucine Rich repeat LRR_7 PF13504.1 KFM06385.1 - 0.017 15.2 11.1 8.2 7.1 0.6 5.6 5 1 1 6 6 6 0 Leucine rich repeat Death PF00531.17 KFM06385.1 - 0.074 12.8 1.0 17 5.2 0.0 3.0 3 0 0 3 3 3 0 Death domain BAAT_C PF08840.6 KFM06386.1 - 1.4e-80 269.9 0.0 1.7e-80 269.7 0.0 1.1 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Bile_Hydr_Trans PF04775.9 KFM06386.1 - 2.3e-15 56.4 0.0 3.4e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA thioester hydrolase/BAAT N-terminal region Abhydrolase_5 PF12695.2 KFM06386.1 - 3.8e-06 26.7 0.0 5.8e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KFM06386.1 - 6.9e-06 25.4 0.2 0.27 10.4 0.0 3.3 2 2 0 2 2 2 2 Dienelactone hydrolase family FSH1 PF03959.8 KFM06386.1 - 2.8e-05 23.6 0.0 4.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 KFM06386.1 - 0.00025 20.3 0.0 0.007 15.6 0.0 2.7 2 1 0 2 2 2 1 Prolyl oligopeptidase family Toxin_16 PF07945.6 KFM06386.1 - 0.065 12.9 0.1 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Janus-atracotoxin RNA_pol_Rpb1_1 PF04997.7 KFM06387.1 - 1.9e-101 339.7 0.9 3.3e-101 338.9 0.6 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 KFM06387.1 - 7.2e-97 323.9 0.1 1.2e-96 323.2 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KFM06387.1 - 2.2e-69 232.6 0.1 4.3e-69 231.7 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 KFM06387.1 - 5.6e-42 143.1 0.0 9.9e-41 139.0 0.0 2.9 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 KFM06387.1 - 1.9e-32 111.1 0.0 6.8e-32 109.4 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 PDZ PF00595.19 KFM06388.1 - 5.6e-46 154.6 9.4 2.3e-13 50.0 0.0 4.6 4 0 0 4 4 4 4 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM06388.1 - 1.1e-23 82.9 2.9 2.7e-06 27.1 0.0 4.8 4 0 0 4 4 4 4 PDZ domain Takusan PF04822.8 KFM06388.1 - 3.2e-16 58.8 0.1 3.2e-16 58.8 0.1 5.1 3 1 3 6 6 6 1 Takusan Guanylate_kin PF00625.16 KFM06388.1 - 1.4e-13 50.7 1.3 1.4e-13 50.7 0.9 4.0 5 2 0 6 6 6 1 Guanylate kinase SH3_1 PF00018.23 KFM06388.1 - 0.032 13.6 0.0 0.072 12.4 0.0 1.7 1 0 0 1 1 1 0 SH3 domain SH3_2 PF07653.12 KFM06388.1 - 0.1 12.0 0.0 0.25 10.8 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain BK_channel_a PF03493.13 KFM06389.1 - 1.3e-29 102.0 0.2 4.5e-29 100.3 0.0 2.1 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.26 KFM06389.1 - 1.9e-16 59.9 16.1 1.9e-16 59.9 11.2 2.2 3 0 0 3 3 3 1 Ion transport protein Ion_trans_2 PF07885.11 KFM06389.1 - 3.6e-14 52.2 2.9 3.6e-14 52.2 2.0 2.5 2 0 0 2 2 2 1 Ion channel TrkA_N PF02254.13 KFM06389.1 - 5.6e-06 26.3 0.1 6.8e-05 22.8 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain Methyltransf_3 PF01596.12 KFM06392.1 - 1.1e-79 266.3 0.1 1.2e-79 266.1 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 KFM06392.1 - 3.9e-15 56.5 0.0 6.1e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFM06392.1 - 1.2e-08 34.7 0.1 1.6e-08 34.2 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFM06392.1 - 4.6e-07 30.4 0.0 7.1e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KFM06392.1 - 0.00011 21.8 0.0 0.00017 21.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 KFM06392.1 - 0.0012 18.0 0.1 0.0018 17.4 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 KFM06392.1 - 0.011 16.1 0.0 0.032 14.7 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 KFM06392.1 - 0.017 15.1 0.0 0.048 13.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KFM06392.1 - 0.032 13.6 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.1 KFM06392.1 - 0.036 14.4 0.0 0.072 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain UPF0146 PF03686.8 KFM06392.1 - 0.085 12.6 0.1 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Porin_3 PF01459.17 KFM06393.1 - 8.1e-79 264.7 5.0 9.1e-79 264.5 3.5 1.0 1 0 0 1 1 1 1 Eukaryotic porin PAP2_C PF14360.1 KFM06394.1 - 3.6e-28 97.6 10.0 3.6e-28 97.6 6.9 2.9 3 0 0 3 3 3 1 PAP2 superfamily C-terminal SAM_1 PF00536.25 KFM06394.1 - 2e-11 43.8 0.0 3.2e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFM06394.1 - 3.7e-06 26.6 0.0 7.4e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Mpv17_PMP22 PF04117.7 KFM06394.1 - 0.017 14.7 0.1 0.062 12.9 0.1 2.0 1 0 0 1 1 1 0 Mpv17 / PMP22 family SAM_PNT PF02198.11 KFM06394.1 - 0.024 14.3 0.2 0.18 11.5 0.0 2.5 3 0 0 3 3 3 0 Sterile alpha motif (SAM)/Pointed domain PAP2 PF01569.16 KFM06394.1 - 0.077 12.6 13.8 0.25 11.0 9.4 2.1 1 1 0 1 1 1 0 PAP2 superfamily PAP2_3 PF14378.1 KFM06394.1 - 1.5 8.3 12.9 2 7.9 8.0 2.0 1 1 1 2 2 2 0 PAP2 superfamily DSPc PF00782.15 KFM06395.1 - 1.6e-27 95.6 0.0 1.9e-27 95.4 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFM06395.1 - 1.8e-05 24.2 0.0 2.2e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF4224 PF13986.1 KFM06395.1 - 0.097 12.2 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) Y_phosphatase3 PF13350.1 KFM06395.1 - 0.13 12.5 0.0 0.38 10.9 0.0 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family Init_tRNA_PT PF04179.7 KFM06395.1 - 0.14 11.0 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase DSPc PF00782.15 KFM06396.1 - 1.6e-30 105.4 0.0 2e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFM06396.1 - 0.0001 21.7 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 KFM06396.1 - 0.00062 18.7 0.0 0.00062 18.7 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase DSPn PF14671.1 KFM06396.1 - 0.008 16.1 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half PTPlike_phytase PF14566.1 KFM06396.1 - 0.031 14.3 0.0 0.044 13.8 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 KFM06396.1 - 0.04 14.1 0.0 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Myotub-related PF06602.9 KFM06396.1 - 0.081 11.6 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Phage_30_3 PF08010.6 KFM06396.1 - 0.1 12.0 0.1 4.3 6.8 0.0 2.6 2 1 1 3 3 3 0 Bacteriophage protein GP30.3 PfkB PF00294.19 KFM06397.1 - 1.7e-73 247.3 0.2 2e-73 247.1 0.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 KFM06397.1 - 0.015 14.5 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase Adap_comp_sub PF00928.16 KFM06398.1 - 1.3e-73 247.2 0.0 1.7e-73 247.0 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KFM06398.1 - 2.4e-06 27.3 0.2 4.9e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Longin PF13774.1 KFM06398.1 - 0.088 12.3 0.1 0.21 11.1 0.1 1.6 1 0 0 1 1 1 0 Regulated-SNARE-like domain Trypsin PF00089.21 KFM06399.1 - 8.5e-68 228.2 0.7 1.1e-67 227.8 0.5 1.1 1 0 0 1 1 1 1 Trypsin Kringle PF00051.13 KFM06399.1 - 2.3e-18 66.0 4.2 4.7e-18 65.0 2.9 1.6 1 0 0 1 1 1 1 Kringle domain hEGF PF12661.2 KFM06399.1 - 0.0014 18.5 3.6 0.0014 18.5 2.5 3.4 3 0 0 3 3 3 1 Human growth factor-like EGF DUF1986 PF09342.6 KFM06399.1 - 0.0017 17.7 0.0 0.0032 16.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 KFM06399.1 - 0.002 18.1 0.0 0.0045 16.9 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain EGF_2 PF07974.8 KFM06399.1 - 0.018 15.2 9.6 0.018 15.2 6.7 2.7 2 0 0 2 2 2 0 EGF-like domain Pkinase PF00069.20 KFM06400.1 - 9e-72 241.3 0.0 1.5e-71 240.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain CaMKII_AD PF08332.5 KFM06400.1 - 1.6e-60 202.6 0.0 2.7e-60 201.8 0.0 1.4 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II Association Pkinase_Tyr PF07714.12 KFM06400.1 - 5.4e-32 110.8 0.0 1.1e-31 109.8 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase DUF4440 PF14534.1 KFM06400.1 - 9.9e-12 45.0 0.0 2.1e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.1 KFM06400.1 - 1.8e-11 44.0 0.0 3.3e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain APH PF01636.18 KFM06400.1 - 0.0091 15.7 0.1 1.9 8.1 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family SnoaL_2 PF12680.2 KFM06400.1 - 0.014 15.8 0.0 0.027 14.8 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like domain Kdo PF06293.9 KFM06400.1 - 0.042 12.9 0.1 0.078 12.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HSNSD PF12062.3 KFM06401.1 - 1.2e-259 861.6 0.0 1.8e-259 861.0 0.0 1.2 1 0 0 1 1 1 1 heparan sulfate-N-deacetylase Sulfotransfer_1 PF00685.22 KFM06401.1 - 3.1e-45 154.5 0.0 4.6e-45 153.9 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 KFM06401.1 - 0.017 16.0 1.3 0.07 14.0 0.2 2.6 2 1 0 2 2 2 0 Sulfotransferase family SWIM PF04434.12 KFM06403.1 - 0.0012 18.3 5.7 0.0023 17.3 4.0 1.5 1 0 0 1 1 1 1 SWIM zinc finger SRCR PF00530.13 KFM06404.1 - 9.6e-46 154.1 9.9 1.2e-30 105.7 2.4 2.3 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 KFM06404.1 - 5.6e-12 45.7 2.8 7.8e-06 26.0 0.2 2.3 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain CHCH PF06747.8 KFM06405.1 - 4.5e-10 39.1 3.7 5.3e-10 38.9 2.6 1.1 1 0 0 1 1 1 1 CHCH domain DUF1903 PF08991.5 KFM06405.1 - 0.00079 19.5 1.2 0.00097 19.2 0.8 1.2 1 1 0 1 1 1 1 Domain of unknown function (DUF1903) Cmc1 PF08583.5 KFM06405.1 - 0.23 11.2 4.1 1.4 8.7 0.5 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Sec23_trunk PF04811.10 KFM06406.1 - 5.3e-90 301.0 0.1 7.7e-90 300.5 0.1 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KFM06406.1 - 2.5e-25 87.8 0.0 4.5e-25 87.0 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KFM06406.1 - 2.9e-19 69.3 0.1 2.6e-18 66.3 0.0 2.4 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KFM06406.1 - 9.2e-16 57.1 10.7 2e-15 56.0 7.4 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KFM06406.1 - 1.1e-10 41.0 0.0 2.7e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat PDZ PF00595.19 KFM06407.1 - 4.9e-11 42.6 0.0 9.5e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Calsarcin PF05556.6 KFM06407.1 - 1.3e-06 27.8 14.0 0.021 14.0 0.2 4.2 3 2 2 5 5 5 3 Calcineurin-binding protein (Calsarcin) Calsarcin PF05556.6 KFM06408.1 - 3.6e-88 295.3 0.1 4.1e-88 295.1 0.1 1.0 1 0 0 1 1 1 1 Calcineurin-binding protein (Calsarcin) p47_phox_C PF08944.6 KFM06408.1 - 0.073 13.2 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain Metallophos PF00149.23 KFM06410.1 - 1.5e-40 138.7 0.3 2.1e-40 138.2 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Annexin PF00191.15 KFM06411.1 - 4.5e-99 324.3 8.4 4.5e-27 93.7 0.3 4.1 4 0 0 4 4 4 4 Annexin MitMem_reg PF13012.1 KFM06412.1 - 1.6e-21 76.4 0.1 2.7e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 KFM06412.1 - 7.5e-07 28.8 0.4 1.3e-06 28.1 0.3 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease AXH PF08517.7 KFM06412.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Ataxin-1 and HBP1 module (AXH) SH3_9 PF14604.1 KFM06413.1 - 2.1e-42 142.4 0.9 7.6e-15 54.2 0.1 4.0 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.23 KFM06413.1 - 1.1e-38 130.3 0.6 8.6e-12 44.2 0.0 4.2 4 0 0 4 4 4 3 SH3 domain SH3_2 PF07653.12 KFM06413.1 - 4.1e-31 106.2 0.3 9.5e-13 47.4 0.0 3.5 3 0 0 3 3 3 3 Variant SH3 domain Sorb PF02208.11 KFM06413.1 - 9.2e-23 79.3 0.6 2.4e-22 78.0 0.4 1.7 1 0 0 1 1 1 1 Sorbin homologous domain PDZ PF00595.19 KFM06414.1 - 2.1e-12 47.0 0.2 5.6e-12 45.6 0.1 1.8 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) LIM PF00412.17 KFM06414.1 - 3.6e-11 42.9 5.5 6.4e-11 42.1 3.8 1.4 1 0 0 1 1 1 1 LIM domain PDZ_2 PF13180.1 KFM06414.1 - 2.9e-05 23.8 0.0 9.9e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 PDZ domain Zn-ribbon_8 PF09723.5 KFM06414.1 - 2 8.4 5.6 15 5.6 2.7 2.7 1 1 2 3 3 3 0 Zinc ribbon domain DZR PF12773.2 KFM06414.1 - 2.3 8.1 5.7 2.7 7.9 2.6 2.1 2 1 0 2 2 2 0 Double zinc ribbon SNF2_N PF00176.18 KFM06415.1 - 1.3e-64 217.8 0.1 4.4e-64 216.1 0.0 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFM06415.1 - 4.4e-18 64.9 0.0 1.6e-17 63.0 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KFM06415.1 - 4.3e-11 42.1 0.2 1e-10 40.9 0.2 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 KFM06415.1 - 3.8e-06 26.8 0.3 0.00011 22.1 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KFM06415.1 - 0.0012 18.4 0.0 0.0026 17.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Shugoshin_C PF07557.6 KFM06415.1 - 0.012 15.1 0.2 0.022 14.2 0.2 1.5 1 0 0 1 1 1 0 Shugoshin C terminus DUF4657 PF15552.1 KFM06416.1 - 4.6e-07 29.4 0.8 4.6e-07 29.4 0.6 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4657) HAP1_N PF04849.8 KFM06416.1 - 0.0021 17.0 1.1 0.0041 16.1 0.8 1.4 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Zona_pellucida PF00100.18 KFM06417.1 - 2.1e-59 201.1 3.4 2.8e-59 200.7 2.4 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain Trefoil PF00088.13 KFM06417.1 - 4.3e-10 39.0 4.1 9.8e-10 37.9 2.8 1.7 1 0 0 1 1 1 1 Trefoil (P-type) domain p450 PF00067.17 KFM06418.1 - 2.4e-136 454.9 0.1 2.8e-136 454.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EMP70 PF02990.11 KFM06419.1 - 2.5e-171 570.6 20.3 3.1e-171 570.3 14.1 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 ATP-synt_8 PF00895.15 KFM06419.1 - 0.16 12.2 7.2 3 8.0 0.0 3.8 3 0 0 3 3 3 0 ATP synthase protein 8 DBB PF14545.1 KFM06420.1 - 4.1e-46 156.0 0.0 6.6e-46 155.3 0.0 1.3 1 0 0 1 1 1 1 Dof, BCAP, and BANK (DBB) motif, SRP40_C PF05022.7 KFM06421.1 - 8.1e-27 93.5 3.4 8.1e-27 93.5 2.3 2.3 2 0 0 2 2 2 1 SRP40, C-terminal domain UDPGT PF00201.13 KFM06422.1 - 8.3e-106 354.4 0.0 9.5e-106 354.3 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 KFM06422.1 - 0.0055 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 KFM06422.1 - 0.0091 15.2 0.0 0.11 11.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 1 ELO PF01151.13 KFM06423.1 - 1.5e-58 198.0 31.6 1.7e-58 197.8 21.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family RVT_2 PF07727.9 KFM06423.1 - 0.022 13.7 0.4 0.037 12.9 0.1 1.4 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Homeobox PF00046.24 KFM06424.1 - 1e-22 79.4 9.2 1.7e-22 78.7 6.4 1.3 1 0 0 1 1 1 1 Homeobox domain OAR PF03826.12 KFM06424.1 - 5.1e-09 35.3 1.4 5.1e-09 35.3 0.9 2.3 2 0 0 2 2 2 1 OAR domain Homeobox_KN PF05920.6 KFM06424.1 - 0.0044 16.6 0.7 0.012 15.2 0.5 1.7 1 0 0 1 1 1 1 Homeobox KN domain Sec7 PF01369.15 KFM06425.1 - 1.9e-58 197.2 0.2 4.3e-58 196.1 0.1 1.6 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 KFM06425.1 - 1.3e-31 109.3 5.7 1.3e-31 109.3 3.9 3.6 3 1 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Frag1 PF10277.4 KFM06426.1 - 5.6e-56 189.4 12.9 6.4e-56 189.2 8.9 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Serinc PF03348.10 KFM06426.1 - 0.027 13.2 3.8 0.021 13.5 1.6 1.6 1 1 1 2 2 2 0 Serine incorporator (Serinc) DUF202 PF02656.10 KFM06426.1 - 2.9 8.1 7.2 88 3.4 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF2768 PF10966.3 KFM06426.1 - 8.7 6.5 8.9 0.68 10.1 1.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2768) RHD PF00554.17 KFM06427.1 - 1.6e-65 219.9 0.1 2.6e-65 219.2 0.0 1.3 1 0 0 1 1 1 1 Rel homology domain (RHD) Ank PF00023.25 KFM06427.1 - 2e-38 128.2 14.9 3.3e-07 29.7 0.0 6.6 6 0 0 6 6 6 6 Ankyrin repeat Ank_2 PF12796.2 KFM06427.1 - 1.9e-36 124.2 8.8 8.4e-19 67.7 0.9 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KFM06427.1 - 2.5e-28 95.3 8.9 0.0014 18.6 0.0 7.1 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 KFM06427.1 - 7e-27 93.3 6.5 1.7e-09 37.9 0.1 5.1 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM06427.1 - 3.2e-25 87.5 10.1 5.5e-08 32.8 0.2 5.8 3 1 2 6 6 6 5 Ankyrin repeats (many copies) Death PF00531.17 KFM06427.1 - 8.4e-10 38.2 0.0 2.6e-09 36.7 0.0 1.9 1 0 0 1 1 1 1 Death domain Sec7 PF01369.15 KFM06428.1 - 4.7e-50 169.8 0.0 9.2e-50 168.9 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 KFM06428.1 - 3.2e-37 127.2 0.1 8.3e-37 125.9 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 KFM06428.1 - 2.6e-10 40.4 0.1 6e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 PH domain F-box PF00646.28 KFM06429.1 - 2.4e-06 27.0 1.2 2.4e-06 27.0 0.8 3.1 3 0 0 3 3 3 1 F-box domain LRR_6 PF13516.1 KFM06429.1 - 6.1e-06 25.7 3.8 11 6.4 0.0 5.9 6 0 0 6 6 6 2 Leucine Rich repeat LRR_4 PF12799.2 KFM06429.1 - 3.8e-05 23.1 5.8 0.62 9.7 0.1 5.3 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM06429.1 - 4.1e-05 23.2 7.3 0.051 13.3 0.0 5.1 3 1 3 6 6 6 4 Leucine rich repeat F-box-like PF12937.2 KFM06429.1 - 0.0066 16.1 0.2 0.0066 16.1 0.1 2.5 2 0 0 2 2 2 1 F-box-like LRR_7 PF13504.1 KFM06429.1 - 0.0092 16.0 10.8 1.3 9.5 0.1 6.7 7 0 0 7 7 7 1 Leucine rich repeat LRR_1 PF00560.28 KFM06429.1 - 0.016 15.1 9.7 3.9 7.8 0.2 6.5 6 3 0 6 6 6 0 Leucine Rich Repeat CUE PF02845.11 KFM06430.1 - 0.0016 17.9 0.1 0.0033 16.8 0.0 1.5 1 0 0 1 1 1 1 CUE domain RE_MjaI PF09568.5 KFM06430.1 - 0.025 14.0 0.8 0.055 13.0 0.5 1.6 1 1 0 1 1 1 0 MjaI restriction endonuclease UCH PF00443.24 KFM06430.1 - 0.036 13.1 0.0 0.044 12.8 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 KFM06430.1 - 0.043 13.6 0.1 0.086 12.7 0.1 1.5 1 0 0 1 1 1 0 UBA/TS-N domain DUF2992 PF11208.3 KFM06430.1 - 0.065 13.1 2.3 0.11 12.4 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Pax2_C PF12403.3 KFM06431.1 - 1.5e-51 172.9 12.8 3.3e-51 171.8 8.9 1.6 1 0 0 1 1 1 1 Paired-box protein 2 C terminal PAX PF00292.13 KFM06431.1 - 2.2e-33 114.6 0.0 4.2e-33 113.7 0.0 1.5 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.1 KFM06431.1 - 6.6e-05 22.4 0.0 0.00014 21.4 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain Homeobox PF00046.24 KFM06431.1 - 0.0043 16.6 0.1 0.015 14.8 0.1 1.9 2 0 0 2 2 2 1 Homeobox domain HTH_Tnp_IS1 PF12759.2 KFM06431.1 - 0.045 13.1 0.0 0.09 12.2 0.0 1.4 1 0 0 1 1 1 0 InsA C-terminal domain Ribosomal_S13_N PF08069.7 KFM06431.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain Cupin_8 PF13621.1 KFM06433.1 - 5.2e-42 144.0 0.4 7.2e-42 143.6 0.3 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KFM06433.1 - 1.5e-07 30.9 0.4 2.2e-07 30.4 0.1 1.4 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.17 KFM06433.1 - 0.029 14.6 0.2 0.16 12.2 0.1 2.2 1 1 0 1 1 1 0 JmjC domain, hydroxylase Cupin_2 PF07883.6 KFM06433.1 - 0.042 13.3 0.0 0.47 9.9 0.0 2.2 2 0 0 2 2 2 0 Cupin domain NDUF_B8 PF05821.6 KFM06434.1 - 3.1e-79 264.7 7.6 3.4e-79 264.6 5.3 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) WD40 PF00400.27 KFM06435.1 - 6.1e-15 54.4 7.9 2e-05 24.2 0.0 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat Sec16_C PF12931.2 KFM06435.1 - 3.7e-05 23.6 0.3 0.00027 20.8 0.2 2.2 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Prp18 PF02840.10 KFM06435.1 - 0.047 13.5 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Prp18 domain wnt PF00110.14 KFM06436.1 - 1.6e-105 352.7 20.7 1.9e-105 352.4 14.3 1.0 1 0 0 1 1 1 1 wnt family FA_desaturase PF00487.19 KFM06437.1 - 4.4e-15 55.8 11.1 7.1e-15 55.1 7.7 1.3 1 0 0 1 1 1 1 Fatty acid desaturase UbiA PF01040.13 KFM06437.1 - 0.054 12.6 4.2 1.1 8.4 0.2 2.5 2 1 0 2 2 2 0 UbiA prenyltransferase family BLOC1_2 PF10046.4 KFM06438.1 - 5.9e-31 106.5 6.0 7.6e-31 106.1 4.2 1.1 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 ParB PF08775.5 KFM06438.1 - 0.0012 19.1 1.7 0.0018 18.5 1.2 1.3 1 0 0 1 1 1 1 ParB family DUF3782 PF12644.2 KFM06438.1 - 0.013 15.3 0.9 0.94 9.3 0.6 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) NPV_P10 PF05531.7 KFM06438.1 - 0.042 14.0 0.3 0.088 13.0 0.1 1.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Phospholip_B PF04916.8 KFM06438.1 - 0.047 11.8 0.4 0.055 11.5 0.3 1.0 1 0 0 1 1 1 0 Phospholipase B DUF948 PF06103.6 KFM06438.1 - 0.061 13.1 0.5 0.49 10.2 0.1 2.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF2443 PF10398.4 KFM06438.1 - 0.062 13.1 0.5 0.097 12.4 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) GlutR_dimer PF00745.15 KFM06438.1 - 0.075 12.9 0.4 0.3 11.0 0.1 1.9 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain p450 PF00067.17 KFM06439.1 - 9.9e-155 515.5 0.2 1.1e-154 515.3 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1819 PF08849.6 KFM06439.1 - 0.017 14.4 0.5 0.82 9.0 0.1 2.3 2 0 0 2 2 2 0 Putative inner membrane protein (DUF1819) RINGv PF12906.2 KFM06440.1 - 1.3e-15 57.1 17.0 4.5e-15 55.4 11.8 2.0 1 0 0 1 1 1 1 RING-variant domain DctQ PF04290.7 KFM06440.1 - 0.0037 17.0 1.0 0.0056 16.4 0.7 1.2 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporters, DctQ component zf-RING_2 PF13639.1 KFM06440.1 - 0.013 15.3 16.3 0.013 15.3 11.3 3.6 5 0 0 5 5 5 0 Ring finger domain ubiquitin PF00240.18 KFM06441.1 - 2.2e-17 62.2 0.0 4.3e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family zf-AN1 PF01428.11 KFM06441.1 - 4.7e-11 42.3 7.6 9e-11 41.4 5.3 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger Rad60-SLD PF11976.3 KFM06441.1 - 1.3e-06 27.9 0.0 3e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KFM06441.1 - 4e-05 23.7 0.0 0.00013 22.1 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain CAP-ZIP_m PF15255.1 KFM06442.1 - 1.4e-58 196.7 6.2 1.4e-58 196.7 4.3 3.8 3 0 0 3 3 3 1 WASH complex subunit CAP-Z interacting, central region PSP94 PF05825.6 KFM06443.1 - 2e-20 72.8 6.9 2.3e-20 72.6 4.8 1.0 1 0 0 1 1 1 1 Beta-microseminoprotein (PSP-94) VWC PF00093.13 KFM06443.1 - 0.0021 18.0 7.2 0.0067 16.5 5.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type C domain PSP94 PF05825.6 KFM06444.1 - 3.5e-26 91.2 10.1 3.8e-26 91.1 7.0 1.0 1 0 0 1 1 1 1 Beta-microseminoprotein (PSP-94) TILa PF12714.2 KFM06444.1 - 0.0095 15.6 9.3 0.018 14.7 6.4 1.8 1 1 0 1 1 1 1 TILa domain VWC PF00093.13 KFM06444.1 - 0.014 15.5 9.7 0.041 13.9 6.7 1.8 1 1 0 1 1 1 0 von Willebrand factor type C domain Pacifastin_I PF05375.8 KFM06444.1 - 0.015 14.8 4.9 0.015 14.8 3.4 2.0 2 1 0 2 2 2 0 Pacifastin inhibitor (LCMII) Fusion_gly PF00523.13 KFM06444.1 - 0.041 11.9 3.7 0.042 11.9 2.5 1.0 1 0 0 1 1 1 0 Fusion glycoprotein F0 zf-Nse PF11789.3 KFM06444.1 - 0.063 12.7 3.4 0.085 12.3 2.3 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit ubiquitin PF00240.18 KFM06445.1 - 1.9e-08 33.5 0.1 2.7e-08 33.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KFM06445.1 - 0.0034 17.0 0.1 0.0042 16.7 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like 7tm_1 PF00001.16 KFM06446.1 - 1.7e-51 174.8 26.3 1.9e-51 174.6 18.2 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM06446.1 - 5.6e-06 25.6 25.7 1.1e-05 24.7 17.8 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF3278 PF11683.3 KFM06446.1 - 4.5 7.2 7.5 3.4 7.6 0.2 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF3278) Git3 PF11710.3 KFM06446.1 - 7.5 6.0 19.8 0.52 9.8 8.9 2.3 1 1 1 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 Annexin PF00191.15 KFM06447.1 - 2.9e-99 324.9 13.7 2.6e-27 94.5 0.4 4.1 4 0 0 4 4 4 4 Annexin Sigma70_ner PF04546.8 KFM06447.1 - 0.0093 15.5 0.0 0.087 12.4 0.0 2.1 2 0 0 2 2 2 1 Sigma-70, non-essential region HTH_27 PF13463.1 KFM06447.1 - 0.12 12.6 0.0 1.7 8.9 0.0 2.3 2 0 0 2 2 2 0 Winged helix DNA-binding domain Ant_C PF05586.6 KFM06448.1 - 9.9e-43 144.5 0.9 1.2e-42 144.2 0.6 1.1 1 0 0 1 1 1 1 Anthrax receptor C-terminus region Anth_Ig PF05587.8 KFM06449.1 - 7.4e-46 154.3 1.1 1.2e-45 153.6 0.7 1.3 1 0 0 1 1 1 1 Anthrax receptor extracellular domain VWA PF00092.23 KFM06449.1 - 4e-11 42.9 0.1 4.3e-06 26.5 0.0 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.1 KFM06449.1 - 3.4e-07 30.5 0.0 5.4e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-C2H2 PF00096.21 KFM06450.1 - 6.4e-05 23.0 30.6 0.016 15.5 4.4 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM06450.1 - 0.0068 16.6 25.6 0.074 13.4 4.0 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger SET PF00856.23 KFM06450.1 - 0.017 15.4 3.0 0.019 15.3 0.0 2.5 2 1 0 2 2 2 0 SET domain DUF4243 PF14027.1 KFM06450.1 - 0.022 14.2 0.0 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4243) zf-C2H2_2 PF12756.2 KFM06450.1 - 0.025 14.6 16.0 1.4 9.0 2.0 3.4 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) GAGA PF09237.6 KFM06450.1 - 0.091 12.3 2.2 0.26 10.9 1.6 1.8 1 0 0 1 1 1 0 GAGA factor zf-C2H2_jaz PF12171.3 KFM06450.1 - 0.45 10.7 20.3 0.59 10.3 1.3 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF349 PF03993.7 KFM06450.1 - 3.3 7.9 10.9 6.4 7.0 0.4 3.2 3 0 0 3 3 3 0 Domain of Unknown Function (DUF349) Uso1_p115_C PF04871.8 KFM06450.1 - 4 7.3 13.7 16 5.4 7.6 2.4 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region zf-met PF12874.2 KFM06450.1 - 4.7 7.5 16.5 0.39 10.9 1.3 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFM06450.1 - 7.6 6.5 20.2 0.14 12.0 1.3 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Peptidase_S41 PF03572.13 KFM06451.1 - 4.7e-128 423.1 0.0 3.5e-33 114.3 0.0 4.2 4 0 0 4 4 4 4 Peptidase family S41 DUF3436 PF11918.3 KFM06451.1 - 1.6e-18 66.6 3.9 2.1e-17 63.1 0.1 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3436) muHD PF10291.4 KFM06451.1 - 0.00015 21.0 0.0 1.5 7.8 0.0 3.7 4 0 0 4 4 4 3 Muniscin C-terminal mu homology domain TGF_beta PF00019.15 KFM06452.1 - 7.1e-35 119.4 0.2 1.6e-34 118.3 0.1 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain Y_phosphatase PF00102.22 KFM06453.1 - 1.1e-73 247.4 0.3 1.4e-73 247.0 0.2 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFM06453.1 - 0.00015 21.3 0.1 0.00026 20.5 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 KFM06453.1 - 0.014 15.4 0.1 0.042 13.8 0.0 1.6 1 1 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 KFM06453.1 - 0.08 13.1 0.0 0.52 10.5 0.0 2.1 2 0 0 2 2 2 0 Tyrosine phosphatase family PDZ PF00595.19 KFM06454.1 - 1e-09 38.3 0.0 1.6e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM06454.1 - 8.8e-06 25.5 0.0 1.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Pkinase PF00069.20 KFM06455.1 - 5e-66 222.4 0.0 6.3e-66 222.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM06455.1 - 1.2e-29 103.1 0.0 1.6e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFM06455.1 - 5.6e-07 28.8 0.1 8.7e-07 28.2 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KFM06455.1 - 5.1e-05 22.3 0.1 9.1e-05 21.5 0.0 1.4 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KFM06455.1 - 0.00034 20.0 0.2 0.00066 19.0 0.1 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KFM06455.1 - 0.00057 19.6 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RhoGAP PF00620.22 KFM06456.1 - 2.4e-48 163.5 0.5 5.6e-48 162.4 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.24 KFM06456.1 - 1.6e-17 63.6 0.0 4.2e-17 62.2 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KFM06456.1 - 2.3e-09 37.4 0.2 7.3e-07 29.4 0.2 2.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 KFM06456.1 - 0.00052 20.0 0.2 0.053 13.5 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.1 KFM06456.1 - 0.0008 19.2 0.0 0.004 17.0 0.0 2.0 2 0 0 2 2 2 1 PH domain ATG16 PF08614.6 KFM06456.1 - 0.0023 17.7 6.4 0.005 16.6 4.4 1.6 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) PspA_IM30 PF04012.7 KFM06456.1 - 0.0079 15.5 8.2 0.013 14.9 5.3 1.6 1 1 0 1 1 1 1 PspA/IM30 family APG6 PF04111.7 KFM06456.1 - 0.018 14.1 8.1 0.032 13.2 5.6 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 KFM06456.1 - 0.23 11.0 17.7 0.046 13.3 9.5 1.8 2 0 0 2 2 2 0 IncA protein PH_9 PF15410.1 KFM06456.1 - 0.25 11.5 2.9 14 5.8 0.1 2.8 3 0 0 3 3 2 0 Pleckstrin homology domain DUF2951 PF11166.3 KFM06456.1 - 0.28 11.0 4.7 0.72 9.7 3.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) Syntaxin-18_N PF10496.4 KFM06456.1 - 0.36 10.6 3.7 12 5.8 0.3 2.6 1 1 1 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus DUF4337 PF14235.1 KFM06456.1 - 0.66 9.8 4.9 1.2 9.0 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) V_ATPase_I PF01496.14 KFM06456.1 - 0.72 7.6 6.8 1.1 7.0 4.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tropomyosin_1 PF12718.2 KFM06456.1 - 1.7 8.5 16.5 2.6 7.9 10.7 1.7 1 1 1 2 2 2 0 Tropomyosin like ADIP PF11559.3 KFM06456.1 - 1.8 8.4 15.3 3.6 7.4 9.2 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.3 KFM06456.1 - 3.3 7.6 13.4 11 5.9 7.3 2.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Striatin PF08232.7 KFM06456.1 - 3.3 8.0 13.7 0.83 9.9 6.7 2.1 2 1 0 2 2 1 0 Striatin family CENP-Q PF13094.1 KFM06456.1 - 8 6.4 19.0 33 4.4 11.2 2.6 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit RIX1 PF08167.7 KFM06457.1 - 0.011 15.3 0.3 0.29 10.8 0.0 2.9 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis SGS PF05002.10 KFM06457.1 - 0.16 11.7 0.0 19 5.0 0.0 2.9 3 0 0 3 3 3 0 SGS domain Beach PF02138.13 KFM06458.1 - 1.9e-111 371.8 0.3 3.2e-111 371.1 0.2 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 KFM06458.1 - 1.8e-12 47.0 0.6 5.1e-12 45.5 0.4 1.9 1 1 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 KFM06458.1 - 9.5e-10 37.9 23.8 1.5e-08 34.1 0.1 5.5 4 1 0 4 4 4 2 WD domain, G-beta repeat LRR_4 PF12799.2 KFM06459.1 - 6.1e-20 70.3 25.1 1.4e-07 30.9 3.1 5.4 2 1 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM06459.1 - 7.3e-17 60.8 17.7 4.4e-08 32.7 0.4 3.7 2 1 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 KFM06459.1 - 2.7e-12 44.9 18.1 0.083 12.9 0.0 7.4 7 1 0 7 7 7 4 Leucine Rich Repeat LRR_7 PF13504.1 KFM06459.1 - 1.2e-09 36.8 11.3 0.22 11.8 0.1 7.6 7 0 0 7 7 7 2 Leucine rich repeat LRR_6 PF13516.1 KFM06459.1 - 0.00026 20.7 13.3 5.3 7.4 0.0 6.3 7 1 0 7 7 7 2 Leucine Rich repeat LEDGF PF11467.3 KFM06459.1 - 0.0024 17.5 1.6 0.39 10.4 0.0 2.5 2 0 0 2 2 2 2 Lens epithelium-derived growth factor (LEDGF) V-set PF07686.12 KFM06460.1 - 7.9e-09 35.4 0.4 1.7e-08 34.3 0.2 1.6 1 1 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 KFM06460.1 - 1.8e-05 24.5 0.0 4.5e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM06460.1 - 7.7e-05 22.7 0.1 0.00031 20.8 0.1 2.0 1 1 0 1 1 1 1 Immunoglobulin domain Shisa PF13908.1 KFM06460.1 - 0.042 14.0 0.1 0.065 13.4 0.1 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Homeobox PF00046.24 KFM06462.1 - 3.7e-25 87.3 5.1 6.4e-25 86.5 3.5 1.4 1 0 0 1 1 1 1 Homeobox domain OAR PF03826.12 KFM06462.1 - 1.5e-07 30.7 4.9 2.8e-07 29.8 1.0 2.6 2 0 0 2 2 2 1 OAR domain Homeobox_KN PF05920.6 KFM06462.1 - 0.024 14.3 0.4 0.093 12.4 0.0 2.1 2 0 0 2 2 2 0 Homeobox KN domain EspF PF04806.7 KFM06462.1 - 0.18 11.9 0.1 0.18 11.9 0.1 2.2 2 0 0 2 2 2 0 EspF protein repeat TP2 PF01254.13 KFM06462.1 - 1 9.6 8.6 0.44 10.8 0.3 2.2 2 0 0 2 2 2 0 Nuclear transition protein 2 TGF_beta PF00019.15 KFM06463.1 - 1.4e-35 121.7 0.4 2.7e-35 120.8 0.3 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.13 KFM06463.1 - 8.8e-26 90.6 1.6 1.2e-25 90.1 1.1 1.2 1 0 0 1 1 1 1 TGF-beta propeptide SNF2_N PF00176.18 KFM06464.1 - 2e-75 253.3 1.3 3.5e-75 252.5 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFM06464.1 - 8.4e-14 51.2 0.0 2.1e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain IL8 PF00048.15 KFM06465.1 - 1.8e-10 40.5 1.1 2.1e-10 40.4 0.8 1.0 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like zf-CSL PF05207.8 KFM06465.1 - 0.077 12.5 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 CSL zinc finger YrvL PF14184.1 KFM06466.1 - 0.029 14.1 0.1 0.042 13.6 0.1 1.2 1 0 0 1 1 1 0 Regulatory protein YrvL Cytochrom_B_N_2 PF13631.1 KFM06466.1 - 0.081 12.7 0.1 0.081 12.7 0.1 1.6 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB Abhydro_lipase PF04083.11 KFM06467.1 - 2.5e-22 77.9 0.1 5.7e-22 76.8 0.0 1.7 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 KFM06467.1 - 9e-19 67.9 0.0 7.7e-18 64.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KFM06467.1 - 1.9e-11 44.2 0.0 2.6e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFM06467.1 - 1.9e-09 37.3 0.0 1.2e-08 34.8 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 KFM06467.1 - 0.014 14.8 0.0 0.44 9.9 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Cutinase PF01083.17 KFM06467.1 - 0.029 14.1 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 Cutinase Abhydro_lipase PF04083.11 KFM06468.1 - 2.5e-23 81.1 0.0 5.2e-23 80.1 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 KFM06468.1 - 2.1e-20 73.2 0.0 1.9e-19 70.1 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KFM06468.1 - 1.7e-11 44.4 0.0 4.1e-11 43.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFM06468.1 - 4.8e-10 39.3 0.1 1.5e-08 34.4 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ank_2 PF12796.2 KFM06469.1 - 4.2e-29 100.7 0.6 1.4e-14 54.1 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFM06469.1 - 2.4e-28 96.5 1.6 8.5e-08 31.6 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 KFM06469.1 - 8.4e-27 92.5 1.8 5.4e-12 45.5 0.1 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFM06469.1 - 2e-24 85.5 5.3 2.8e-08 34.0 0.0 4.1 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM06469.1 - 2.6e-20 70.4 2.7 2.8e-05 23.9 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat DUF3098 PF11297.3 KFM06469.1 - 0.015 15.0 0.7 0.029 14.0 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3098) DUF3447 PF11929.3 KFM06469.1 - 0.58 9.9 3.6 0.62 9.9 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3447) Abhydro_lipase PF04083.11 KFM06470.1 - 1.9e-23 81.6 0.0 4e-23 80.5 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 KFM06470.1 - 1.1e-16 61.1 0.0 3.5e-16 59.4 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KFM06470.1 - 1.4e-09 38.1 0.0 2.7e-09 37.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFM06470.1 - 4.6e-09 36.1 0.2 1.1e-07 31.7 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family USP8_dimer PF08969.6 KFM06471.1 - 5.4e-15 55.3 0.0 7.8e-15 54.8 0.0 1.3 1 1 0 1 1 1 1 USP8 dimerisation domain TPR_8 PF13181.1 KFM06471.1 - 0.017 14.8 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Actin PF00022.14 KFM06472.1 - 4.1e-162 539.0 0.0 4.7e-162 538.8 0.0 1.0 1 0 0 1 1 1 1 Actin FA_hydroxylase PF04116.8 KFM06473.1 - 2.1e-14 53.8 18.2 2.1e-14 53.8 12.6 2.0 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Abhydrolase_1 PF00561.15 KFM06474.1 - 2e-26 93.0 0.1 2.5e-26 92.6 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.11 KFM06474.1 - 5.5e-23 80.0 0.0 1.3e-22 78.8 0.0 1.7 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 KFM06474.1 - 1.5e-10 41.3 0.0 2.8e-10 40.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFM06474.1 - 2e-10 40.5 0.0 7.5e-10 38.7 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 KFM06474.1 - 0.0027 17.1 0.0 0.016 14.6 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Lipase_3 PF01764.20 KFM06474.1 - 0.048 13.2 0.0 0.092 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) AXE1 PF05448.7 KFM06474.1 - 0.06 11.8 0.0 1.1 7.7 0.0 2.2 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF2974 PF11187.3 KFM06474.1 - 0.088 12.1 0.1 0.18 11.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.3 KFM06474.1 - 0.13 12.1 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase TPR_11 PF13414.1 KFM06475.1 - 1.2e-26 92.1 30.6 3.2e-06 26.7 0.1 7.1 5 2 2 7 7 7 6 TPR repeat TPR_12 PF13424.1 KFM06475.1 - 2.1e-24 85.2 18.6 3.4e-07 30.1 0.2 6.2 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 KFM06475.1 - 2.5e-22 77.3 0.2 0.00037 20.8 0.0 8.2 5 2 4 9 9 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 KFM06475.1 - 3e-20 70.4 27.4 0.00048 19.8 0.1 10.5 11 1 0 11 11 10 4 Tetratricopeptide repeat TPR_1 PF00515.23 KFM06475.1 - 2.8e-18 64.6 25.1 0.00011 21.6 0.0 9.4 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 KFM06475.1 - 1.8e-17 63.4 5.2 0.00043 20.5 0.1 6.4 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 KFM06475.1 - 2.1e-15 55.2 27.1 0.0049 16.5 0.1 8.7 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.1 KFM06475.1 - 4e-15 56.0 9.9 0.00017 22.1 0.3 6.0 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFM06475.1 - 8.2e-13 47.4 23.6 0.088 13.0 0.0 9.4 11 0 0 11 11 9 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFM06475.1 - 2.5e-09 36.2 9.9 0.044 13.6 0.0 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_15 PF13429.1 KFM06475.1 - 2.1e-07 30.3 8.4 0.0019 17.3 0.1 4.6 2 2 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 KFM06475.1 - 2.7e-07 30.2 0.5 0.12 12.3 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 KFM06475.1 - 5.1e-07 29.7 20.3 0.13 12.3 0.4 5.6 4 2 1 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KFM06475.1 - 8.6e-07 28.7 0.3 1.1 9.1 0.0 5.5 4 1 3 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFM06475.1 - 8.1e-06 25.9 17.9 0.82 10.2 0.1 8.1 9 1 0 9 9 9 1 Tetratricopeptide repeat NARP1 PF12569.3 KFM06475.1 - 0.00018 20.4 0.1 0.00018 20.4 0.0 4.1 2 2 3 5 5 5 1 NMDA receptor-regulated protein 1 TPR_20 PF14561.1 KFM06475.1 - 0.0051 16.9 1.6 5.1 7.2 0.0 5.0 5 1 1 6 6 6 1 Tetratricopeptide repeat IF-2B PF01008.12 KFM06475.1 - 0.018 14.0 0.1 0.031 13.2 0.1 1.3 1 0 0 1 1 1 0 Initiation factor 2 subunit family PPR PF01535.15 KFM06475.1 - 0.031 14.2 2.1 13 6.0 0.0 3.5 4 0 0 4 4 2 0 PPR repeat SPOB_a PF14689.1 KFM06475.1 - 0.57 9.7 4.8 18 4.9 0.1 4.1 5 0 0 5 5 5 0 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_3 PF07720.7 KFM06475.1 - 0.8 9.5 8.3 0.64 9.8 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KFM06475.1 - 1.3 8.9 13.0 1.8 8.5 0.0 5.7 7 0 0 7 7 6 0 Fis1 C-terminal tetratricopeptide repeat MFS_1 PF07690.11 KFM06476.1 - 6.1e-34 117.2 32.2 1.9e-19 69.5 5.5 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KFM06476.1 - 9e-05 22.1 7.0 0.14 12.0 0.2 4.1 4 1 0 4 4 4 2 MFS_1 like family Fumble PF03630.9 KFM06477.1 - 9.9e-147 488.2 0.1 1.1e-146 488.0 0.1 1.0 1 0 0 1 1 1 1 Fumble 7tm_1 PF00001.16 KFM06479.1 - 7.2e-82 274.3 12.6 8.7e-82 274.1 8.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM06479.1 - 1.7e-08 33.9 12.7 3e-08 33.1 8.8 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM06479.1 - 0.0042 16.2 11.7 0.0042 16.2 8.1 2.2 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF4491 PF14898.1 KFM06479.1 - 1.4 9.1 7.4 1.6 8.9 0.4 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4491) RNase_P_p30 PF01876.11 KFM06480.1 - 2e-52 176.4 0.0 2.5e-52 176.1 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 Ank_2 PF12796.2 KFM06481.1 - 2.3e-38 130.4 0.6 6.7e-21 74.4 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFM06481.1 - 2.1e-37 125.0 0.1 3.2e-09 36.1 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 KFM06481.1 - 2.2e-34 116.6 5.6 7e-10 38.8 0.1 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFM06481.1 - 1.5e-30 105.0 0.5 1.7e-10 41.1 0.1 4.0 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM06481.1 - 2.3e-29 98.4 0.0 7e-06 25.8 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat HlyU PF10115.4 KFM06481.1 - 0.052 13.3 0.1 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Transcriptional activator HlyU zf-C3HC4 PF00097.20 KFM06482.1 - 5e-08 32.4 11.5 5e-08 32.4 8.0 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM06482.1 - 4.4e-07 29.8 11.1 4.4e-07 29.8 7.7 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM06482.1 - 2.7e-05 23.8 9.5 2.7e-05 23.8 6.6 2.5 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 KFM06482.1 - 0.00012 21.7 10.5 0.00012 21.7 7.3 3.3 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFM06482.1 - 0.00015 21.5 10.5 0.00015 21.5 7.3 3.2 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 KFM06482.1 - 0.0021 17.6 8.4 0.0021 17.6 5.8 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 KFM06482.1 - 0.0053 16.2 7.5 0.01 15.3 5.2 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 KFM06482.1 - 0.031 14.0 3.0 0.031 14.0 2.1 2.5 3 0 0 3 3 3 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 KFM06482.1 - 0.12 12.0 10.0 0.056 13.1 4.4 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-rbx1 PF12678.2 KFM06482.1 - 1.6 8.8 11.8 1.5 8.9 5.8 2.7 2 1 0 2 2 2 0 RING-H2 zinc finger CBM_21 PF03370.8 KFM06483.1 - 1.3e-36 124.9 2.8 1.8e-36 124.5 1.9 1.2 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit CBM_25 PF03423.8 KFM06483.1 - 0.0014 18.6 0.4 0.0032 17.5 0.3 1.6 1 0 0 1 1 1 1 Carbohydrate binding domain (family 25) Ank PF00023.25 KFM06484.1 - 6.6e-135 432.7 49.5 6.7e-12 44.5 0.2 18.5 21 0 0 21 21 21 15 Ankyrin repeat Ank_2 PF12796.2 KFM06484.1 - 1.4e-133 435.5 50.7 3.1e-23 81.9 2.4 9.6 3 3 6 10 10 10 10 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFM06484.1 - 1.6e-108 352.3 50.2 3.5e-14 52.4 0.2 15.8 5 5 13 18 18 18 15 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFM06484.1 - 4.1e-107 348.8 24.2 4.1e-14 52.6 0.2 14.7 7 5 7 15 15 15 15 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM06484.1 - 1.4e-94 300.4 32.4 2e-07 30.5 0.1 18.2 20 0 0 20 20 20 15 Ankyrin repeat PARP PF00644.15 KFM06484.1 - 9.1e-27 93.8 3.8 2.6e-24 85.8 2.6 2.4 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain SAM_2 PF07647.12 KFM06484.1 - 1.4e-13 50.4 0.1 3.5e-13 49.1 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFM06484.1 - 4e-11 42.9 0.2 9.5e-11 41.7 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Shigella_OspC PF06128.6 KFM06484.1 - 4.9e-06 26.2 0.0 1.5 8.2 0.0 4.8 4 0 0 4 4 4 1 Shigella flexneri OspC protein Vps39_1 PF10366.4 KFM06484.1 - 0.0002 21.3 1.0 1 9.4 0.0 3.5 4 0 0 4 4 4 2 Vacuolar sorting protein 39 domain 1 7tm_1 PF00001.16 KFM06485.1 - 2.6e-81 272.5 11.8 3.4e-81 272.1 8.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM06485.1 - 7.9e-11 41.5 6.1 3.2e-10 39.6 4.3 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM06485.1 - 2.8e-06 26.6 13.7 5.7e-06 25.6 4.6 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx DUF3390 PF11870.3 KFM06485.1 - 0.17 11.8 0.6 12 5.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3390) DUF621 PF04789.10 KFM06485.1 - 2.2 7.2 10.4 5.9 5.7 7.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF621) RabGAP-TBC PF00566.13 KFM06486.1 - 1.1e-46 159.0 0.0 1.9e-46 158.2 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CBF PF03914.12 KFM06487.1 - 1.3e-38 132.0 0.3 1.3e-38 132.0 0.2 2.4 2 0 0 2 2 2 1 CBF/Mak21 family NOC3p PF07540.6 KFM06487.1 - 2e-33 114.5 3.1 2e-33 114.5 2.1 3.1 3 0 0 3 3 3 1 Nucleolar complex-associated protein PI-PLC-Y PF00387.14 KFM06488.1 - 6.7e-34 116.4 0.0 1.5e-33 115.2 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain RA PF00788.18 KFM06488.1 - 5.6e-25 87.6 0.0 3.3e-19 69.1 0.1 2.5 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain C2 PF00168.25 KFM06488.1 - 8.2e-10 38.3 0.0 1.9e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 C2 domain DUF360 PF04020.8 KFM06489.1 - 0.051 13.9 0.3 0.055 13.8 0.2 1.1 1 0 0 1 1 1 0 Membrane protein of unknown function EPTP PF03736.12 KFM06490.1 - 3.1e-94 308.5 21.3 1.1e-15 57.0 0.0 7.2 7 0 0 7 7 7 7 EPTP domain LRR_8 PF13855.1 KFM06490.1 - 2.8e-23 81.4 9.6 2.6e-15 55.9 3.0 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 KFM06490.1 - 6.5e-10 38.3 5.4 2.4e-05 23.8 1.4 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFM06490.1 - 9.2e-08 31.8 0.9 9.2e-08 31.8 0.6 2.1 2 0 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_1 PF00560.28 KFM06490.1 - 3.8e-06 26.1 10.3 0.006 16.4 0.4 4.9 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_9 PF14580.1 KFM06490.1 - 0.062 12.8 0.3 0.11 12.0 0.2 1.4 1 0 0 1 1 1 0 Leucine-rich repeat LRR_7 PF13504.1 KFM06490.1 - 0.14 12.4 4.6 5.9 7.5 0.4 3.6 3 0 0 3 3 3 0 Leucine rich repeat LRR_6 PF13516.1 KFM06490.1 - 3.6 7.9 6.6 39 4.7 0.3 3.7 3 0 0 3 3 3 0 Leucine Rich repeat Fra10Ac1 PF09725.4 KFM06491.1 - 5.8e-53 177.9 5.5 5.8e-53 177.9 3.8 2.5 3 0 0 3 3 3 1 Folate-sensitive fragile site protein Fra10Ac1 GET2 PF08690.5 KFM06491.1 - 0.77 8.9 3.4 1.2 8.3 2.3 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 FYDLN_acid PF09538.5 KFM06491.1 - 2.2 8.8 12.1 0.8 10.3 4.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) PDEase_I PF00233.14 KFM06492.1 - 1.2e-90 303.3 2.4 1.2e-90 303.3 1.7 1.7 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.21 KFM06492.1 - 1e-37 129.6 0.0 7.7e-18 65.0 0.0 2.3 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.1 KFM06492.1 - 4.7e-14 52.5 0.0 3.3e-09 36.9 0.0 2.7 2 1 0 2 2 2 2 GAF domain GAF_2 PF13185.1 KFM06492.1 - 4.9e-10 40.0 0.0 0.001 19.5 0.0 2.3 2 0 0 2 2 2 2 GAF domain FPL PF09758.4 KFM06492.1 - 0.012 15.3 2.1 0.023 14.4 0.5 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein DUF4316 PF14195.1 KFM06492.1 - 0.03 14.3 0.3 0.08 13.0 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) Lipocalin PF00061.18 KFM06493.1 - 4.5e-24 85.0 0.0 5.2e-24 84.8 0.0 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_2 PF08212.7 KFM06493.1 - 3.8e-06 26.7 0.2 6e-06 26.0 0.1 1.3 1 1 0 1 1 1 1 Lipocalin-like domain Triabin PF03973.8 KFM06493.1 - 0.00098 18.8 0.0 0.0017 18.0 0.0 1.4 2 0 0 2 2 2 1 Triabin EABR PF12180.3 KFM06494.1 - 5.8e-18 63.9 1.9 1.9e-17 62.3 1.3 2.0 1 0 0 1 1 1 1 TSG101 and ALIX binding domain of CEP55 ADIP PF11559.3 KFM06494.1 - 0.00018 21.4 19.3 0.00018 21.4 13.4 4.8 2 2 3 5 5 5 3 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 KFM06494.1 - 3.9 6.5 11.6 1.5 7.9 1.4 2.8 2 1 0 2 2 2 0 Reovirus sigma C capsid protein p450 PF00067.17 KFM06495.1 - 1.6e-65 221.4 0.0 1.9e-65 221.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Homeobox PF00046.24 KFM06496.1 - 1.2e-21 76.0 4.7 2.2e-21 75.1 3.2 1.5 1 0 0 1 1 1 1 Homeobox domain ArsC PF03960.10 KFM06496.1 - 0.00055 19.9 0.4 0.00092 19.2 0.2 1.4 1 0 0 1 1 1 1 ArsC family Homeobox_KN PF05920.6 KFM06496.1 - 0.0073 15.9 0.6 0.013 15.1 0.1 1.7 2 0 0 2 2 2 1 Homeobox KN domain Homez PF11569.3 KFM06496.1 - 0.011 14.7 0.3 0.024 13.7 0.2 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Kinesin PF00225.18 KFM06497.1 - 7.4e-116 386.5 0.1 7.4e-116 386.5 0.0 3.4 3 0 0 3 3 3 2 Kinesin motor domain Microtub_bind PF13931.1 KFM06497.1 - 6.3e-43 146.3 3.7 6.3e-43 146.3 2.6 4.6 4 2 0 5 5 5 1 Kinesin-associated microtubule-binding RINGv PF12906.2 KFM06498.1 - 5e-14 52.0 9.9 7.5e-14 51.5 6.9 1.3 1 0 0 1 1 1 1 RING-variant domain DUF2517 PF10725.4 KFM06498.1 - 0.00038 20.0 0.1 0.0009 18.8 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2517) zf-RING_2 PF13639.1 KFM06498.1 - 0.00055 19.7 6.0 0.0012 18.6 4.2 1.6 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 KFM06498.1 - 0.034 14.0 5.7 0.075 13.0 3.9 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 KFM06498.1 - 0.28 10.8 4.9 0.6 9.7 3.4 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-CSL PF05207.8 KFM06498.1 - 0.51 9.8 3.4 1.7 8.2 2.4 1.8 1 1 0 1 1 1 0 CSL zinc finger PHD PF00628.24 KFM06498.1 - 2.3 8.0 8.3 3.9 7.2 5.8 1.4 1 0 0 1 1 1 0 PHD-finger RRM_1 PF00076.17 KFM06500.1 - 2.5e-12 46.2 0.0 3.1e-07 29.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM06500.1 - 6.2e-07 29.3 0.0 2.2e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-U1 PF06220.7 KFM06500.1 - 0.031 13.8 0.6 0.072 12.6 0.4 1.6 1 0 0 1 1 1 0 U1 zinc finger zf-B_box PF00643.19 KFM06500.1 - 0.096 12.5 6.3 0.25 11.2 4.4 1.6 1 0 0 1 1 1 0 B-box zinc finger HSP20 PF00011.16 KFM06500.1 - 0.1 12.4 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 Hsp20/alpha crystallin family SKG6 PF08693.5 KFM06500.1 - 0.85 8.9 2.5 1.8 7.9 1.8 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3535 PF12054.3 KFM06501.1 - 6.3e-138 460.1 5.9 1.9e-136 455.2 3.0 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 KFM06501.1 - 8.3e-68 228.3 0.0 1.5e-67 227.4 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 KFM06501.1 - 6e-22 75.7 20.5 0.0021 17.9 0.0 13.0 12 0 0 12 12 12 6 HEAT repeat HEAT_2 PF13646.1 KFM06501.1 - 1.2e-14 54.2 0.6 0.0012 19.0 0.0 7.5 4 2 3 7 7 7 5 HEAT repeats Helicase_C PF00271.26 KFM06501.1 - 3.9e-13 49.0 0.0 9.9e-13 47.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Vac14_Fab1_bd PF12755.2 KFM06501.1 - 6.6e-12 45.6 0.2 0.0091 16.3 0.0 5.5 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KFM06501.1 - 8.5e-10 38.8 11.0 0.0044 17.4 0.1 9.4 9 2 1 10 10 10 1 HEAT-like repeat Arm PF00514.18 KFM06501.1 - 0.019 14.7 4.7 0.14 12.0 0.0 4.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DUF4559 PF15112.1 KFM06502.1 - 0.022 13.9 0.4 0.026 13.6 0.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Cyclin_C PF02984.14 KFM06504.1 - 2.1e-26 92.1 9.7 1.5e-25 89.3 0.2 3.0 3 0 0 3 3 3 2 Cyclin, C-terminal domain Cyclin_N PF00134.18 KFM06504.1 - 3.9e-18 65.2 0.9 3.9e-18 65.2 0.6 2.5 3 1 1 4 4 4 1 Cyclin, N-terminal domain zf-C2H2_4 PF13894.1 KFM06505.1 - 1.1e-05 25.4 42.9 0.042 14.1 1.9 7.9 6 1 1 7 7 7 4 C2H2-type zinc finger zf-C2H2 PF00096.21 KFM06505.1 - 0.00034 20.7 49.9 0.031 14.6 0.2 7.8 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM06505.1 - 0.0021 18.2 42.8 0.042 14.1 0.5 7.9 7 0 0 7 7 7 4 Zinc-finger double domain SH2 PF00017.19 KFM06506.1 - 1.8e-10 40.4 0.1 3.5e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 SH2 domain DUF2862 PF11061.3 KFM06506.1 - 0.077 12.7 0.2 0.15 11.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2862) DNA_pol_lambd_f PF10391.4 KFM06507.1 - 5.1e-22 77.1 0.1 9.5e-22 76.3 0.1 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.1 KFM06507.1 - 1.4e-20 72.6 0.2 4.6e-20 71.0 0.1 1.9 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.1 KFM06507.1 - 3.5e-15 55.9 0.0 9.9e-15 54.4 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_B_palm PF14792.1 KFM06507.1 - 2.9e-08 33.7 0.0 7.5e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta palm BRCT PF00533.21 KFM06507.1 - 2.4e-07 30.8 0.0 5.9e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain NTP_transf_2 PF01909.18 KFM06507.1 - 0.00032 20.9 0.0 0.00074 19.7 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Cdd1 PF11731.3 KFM06507.1 - 0.012 15.5 0.0 0.037 13.9 0.0 1.9 1 1 0 1 1 1 0 Pathogenicity locus HHH_5 PF14520.1 KFM06507.1 - 0.12 12.5 0.0 0.51 10.5 0.0 2.0 1 1 0 1 1 1 0 Helix-hairpin-helix domain Sulfotransfer_1 PF00685.22 KFM06508.1 - 1.5e-32 112.8 0.1 2.1e-32 112.4 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain 7tm_2 PF00002.19 KFM06509.1 - 2.4e-13 49.7 7.6 4.8e-13 48.7 5.2 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) I-set PF07679.11 KFM06509.1 - 2.6e-07 30.4 0.0 4.9e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain GPS PF01825.16 KFM06509.1 - 1.5e-06 28.1 1.8 2.1e-06 27.7 0.0 2.3 2 0 0 2 2 2 1 Latrophilin/CL-1-like GPS domain LRR_8 PF13855.1 KFM06509.1 - 7.7e-06 25.5 7.3 9.1e-06 25.3 3.5 2.4 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.2 KFM06509.1 - 0.007 15.9 1.5 0.02 14.4 1.0 1.8 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM06509.1 - 0.42 10.8 5.5 8.7 6.8 0.6 3.9 3 0 0 3 3 3 0 Leucine Rich Repeat Neur_chan_LBD PF02931.18 KFM06510.1 - 5.4e-52 176.0 0.1 7.3e-52 175.6 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFM06510.1 - 4.7e-30 105.2 9.5 2.6e-27 96.2 3.8 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region GDA1_CD39 PF01150.12 KFM06512.1 - 8.4e-129 429.8 0.1 1e-128 429.5 0.1 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Peptidase_M14 PF00246.19 KFM06513.1 - 5.6e-83 278.7 0.1 6.8e-83 278.4 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.1 KFM06513.1 - 1.6e-14 53.7 0.4 2.9e-14 52.8 0.3 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 KFM06513.1 - 9.4e-06 25.5 0.0 1.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4480) AstE_AspA PF04952.9 KFM06513.1 - 0.033 13.0 0.2 0.094 11.5 0.1 1.8 1 1 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family DUF2817 PF10994.3 KFM06513.1 - 0.097 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) Cna_B PF05738.8 KFM06513.1 - 0.2 11.4 1.0 0.67 9.7 0.0 2.4 3 0 0 3 3 3 0 Cna protein B-type domain RhoGEF PF00621.15 KFM06514.1 - 1.1e-22 80.7 1.0 1.3e-22 80.5 0.7 1.0 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.13 KFM06515.1 - 5.8e-45 153.5 3.1 8.5e-45 153.0 2.2 1.2 1 0 0 1 1 1 1 BAR domain RhoGEF PF00621.15 KFM06515.1 - 1.7e-14 54.0 0.0 1.7e-14 54.0 0.0 2.2 2 1 0 2 2 2 1 RhoGEF domain SH3_2 PF07653.12 KFM06515.1 - 7.6e-13 47.7 0.0 1.4e-06 27.6 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.1 KFM06515.1 - 5.7e-12 45.0 0.0 2.6e-09 36.5 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KFM06515.1 - 1.3e-11 43.7 0.0 1.4e-07 30.8 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_3 PF08239.6 KFM06515.1 - 0.14 12.4 0.3 0.93 9.7 0.1 2.1 2 0 0 2 2 2 0 Bacterial SH3 domain ABC_membrane PF00664.18 KFM06516.1 - 7.7e-74 248.5 37.4 3.1e-40 138.3 10.1 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFM06516.1 - 3.3e-51 173.1 1.1 3e-27 95.5 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.14 KFM06516.1 - 1.4e-10 40.7 0.0 0.00033 19.9 0.0 4.0 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KFM06516.1 - 8.6e-09 35.6 0.6 0.0075 16.2 0.1 3.3 3 0 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.18 KFM06516.1 - 1.4e-06 28.1 0.1 0.023 14.6 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.1 KFM06516.1 - 1.8e-06 28.1 0.1 4.1 7.2 0.0 4.6 2 2 0 3 3 3 1 AAA domain Miro PF08477.8 KFM06516.1 - 6.6e-06 26.6 0.3 0.016 15.7 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 KFM06516.1 - 3.2e-05 23.3 2.2 0.035 13.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 KFM06516.1 - 0.00012 21.3 0.5 0.51 9.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 ArgK PF03308.11 KFM06516.1 - 0.00014 20.6 0.1 0.0096 14.7 0.0 2.6 3 0 0 3 3 2 1 ArgK protein DUF87 PF01935.12 KFM06516.1 - 0.00032 20.5 8.0 0.042 13.6 0.2 3.5 3 0 0 3 3 3 2 Domain of unknown function DUF87 AAA_10 PF12846.2 KFM06516.1 - 0.00046 19.7 4.1 0.028 13.8 0.0 3.1 3 1 1 4 4 4 1 AAA-like domain Dynamin_N PF00350.18 KFM06516.1 - 0.00067 19.5 3.7 0.087 12.6 0.4 2.6 2 0 0 2 2 2 2 Dynamin family Zeta_toxin PF06414.7 KFM06516.1 - 0.00082 18.5 2.0 0.8 8.7 0.2 2.5 2 0 0 2 2 2 2 Zeta toxin DUF815 PF05673.8 KFM06516.1 - 0.0023 16.9 0.2 0.81 8.5 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_25 PF13481.1 KFM06516.1 - 0.0032 16.8 0.0 0.19 11.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KFM06516.1 - 0.0064 16.1 1.4 3.2 7.4 0.1 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 KFM06516.1 - 0.0066 17.2 0.1 13 6.6 0.0 3.5 4 0 0 4 4 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KFM06516.1 - 0.01 15.3 0.1 1 8.7 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_22 PF13401.1 KFM06516.1 - 0.012 15.7 1.9 15 5.7 0.0 3.7 2 1 1 3 3 3 0 AAA domain T2SE PF00437.15 KFM06516.1 - 0.024 13.5 0.1 5.3 5.8 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein ATP_bind_1 PF03029.12 KFM06516.1 - 0.028 13.9 0.7 1.4 8.3 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_30 PF13604.1 KFM06516.1 - 0.035 13.6 2.3 3.8 7.0 0.1 3.3 3 0 0 3 3 3 0 AAA domain GTP_EFTU PF00009.22 KFM06516.1 - 0.061 12.7 0.1 10 5.5 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_ATPase PF09818.4 KFM06516.1 - 0.088 11.3 0.1 0.73 8.3 0.0 2.4 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_33 PF13671.1 KFM06516.1 - 0.13 12.0 0.1 6.5 6.6 0.1 2.7 2 0 0 2 2 2 0 AAA domain Ribosomal_S4 PF00163.14 KFM06516.1 - 0.29 11.5 5.0 0.82 10.0 3.0 2.1 1 1 1 2 2 2 0 Ribosomal protein S4/S9 N-terminal domain AAA_23 PF13476.1 KFM06516.1 - 0.73 10.1 0.0 0.73 10.1 0.0 3.4 4 0 0 4 4 3 0 AAA domain CutC PF03932.9 KFM06517.1 - 1.3e-56 191.0 0.0 2.6e-56 190.1 0.0 1.4 2 0 0 2 2 2 1 CutC family COX15-CtaA PF02628.10 KFM06518.1 - 2.3e-84 282.8 6.9 2.6e-84 282.6 4.8 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein GDA1_CD39 PF01150.12 KFM06519.1 - 1.8e-79 267.3 0.0 2.3e-79 266.9 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Mito_carr PF00153.22 KFM06520.1 - 1.3e-42 143.3 1.4 2.2e-20 72.1 0.4 2.0 1 1 1 2 2 2 2 Mitochondrial carrier protein NDUF_B6 PF09782.4 KFM06520.1 - 0.043 13.6 0.7 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit Aminotran_1_2 PF00155.16 KFM06521.1 - 5.7e-88 295.2 0.0 6.7e-88 295.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Glyco_hydro_79n PF03662.9 KFM06523.1 - 1.1e-20 73.5 1.2 3.6e-20 71.8 0.2 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 79, N-terminal domain Mon1 PF03164.9 KFM06524.1 - 0.013 14.0 0.0 2.8 6.4 0.0 2.4 2 0 0 2 2 2 0 Trafficking protein Mon1 DUF2414 PF10309.4 KFM06525.1 - 0.00072 19.1 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) RNA_bind PF08675.6 KFM06525.1 - 0.002 18.0 0.0 0.0034 17.3 0.0 1.3 1 0 0 1 1 1 1 RNA binding domain VCBS PF13517.1 KFM06526.1 - 2.9e-32 110.8 10.6 5.1e-11 42.7 0.9 4.9 3 1 1 4 4 4 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 KFM06526.1 - 1.2e-17 63.0 21.4 4.6e-05 22.9 0.2 5.6 5 0 0 5 5 5 4 FG-GAP repeat UnbV_ASPIC PF07593.7 KFM06526.1 - 2.4e-13 49.5 0.0 6e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 ASPIC and UnbV EGF_CA PF07645.10 KFM06526.1 - 7.5e-10 38.6 7.3 7.5e-10 38.6 5.0 1.9 2 0 0 2 2 2 1 Calcium-binding EGF domain cEGF PF12662.2 KFM06526.1 - 0.016 14.8 10.3 0.7 9.5 1.7 2.9 2 0 0 2 2 2 0 Complement Clr-like EGF-like TcdB_toxin_midN PF12256.3 KFM06526.1 - 0.12 11.8 4.0 5.3 6.4 0.0 3.8 3 1 1 4 4 4 0 Insecticide toxin TcdB middle/N-terminal region Erf4 PF10256.4 KFM06527.1 - 3.9e-33 113.7 0.0 4.3e-33 113.6 0.0 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF3920 PF13058.1 KFM06527.1 - 0.054 13.3 0.1 0.069 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3920) Fz PF01392.17 KFM06528.1 - 2.8e-32 111.4 6.3 6e-32 110.4 4.4 1.5 1 0 0 1 1 1 1 Fz domain NTR PF01759.16 KFM06528.1 - 2.8e-16 59.0 0.3 4.3e-16 58.4 0.2 1.3 1 0 0 1 1 1 1 UNC-6/NTR/C345C module TIMP PF00965.12 KFM06528.1 - 0.02 14.5 0.2 0.033 13.7 0.1 1.3 1 0 0 1 1 1 0 Tissue inhibitor of metalloproteinase FYVE PF01363.16 KFM06529.1 - 2.5e-08 33.6 11.1 2.5e-08 33.6 7.7 2.1 3 0 0 3 3 3 1 FYVE zinc finger FYVE_2 PF02318.11 KFM06529.1 - 0.00016 21.5 7.3 0.00016 21.5 5.0 2.1 2 0 0 2 2 2 1 FYVE-type zinc finger Pex24p PF06398.6 KFM06529.1 - 0.088 11.5 0.1 0.23 10.1 0.0 1.5 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin Dpy-30 PF05186.8 KFM06529.1 - 0.1 12.0 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 Dpy-30 motif Reticulon PF02453.12 KFM06529.1 - 0.13 11.8 5.4 1 8.9 0.2 2.3 2 0 0 2 2 2 0 Reticulon IBR PF01485.16 KFM06529.1 - 2.3 8.1 13.1 0.16 11.8 4.3 2.6 3 0 0 3 3 3 0 IBR domain MARVEL PF01284.18 KFM06530.1 - 3.6e-07 30.0 10.7 4.3e-07 29.8 7.4 1.1 1 0 0 1 1 1 1 Membrane-associating domain PI3_PI4_kinase PF00454.22 KFM06531.1 - 1.2e-56 191.8 0.0 1.5e-56 191.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase MORN PF02493.15 KFM06532.1 - 5e-28 95.1 20.4 3.1e-08 32.8 0.2 5.6 6 0 0 6 6 6 4 MORN repeat HCBP_related PF06594.6 KFM06532.1 - 0.00054 19.5 0.2 0.095 12.3 0.0 2.7 3 0 0 3 3 3 2 Haemolysin-type calcium binding protein related domain DHDPS PF00701.17 KFM06533.1 - 3.2e-53 180.2 0.0 3.7e-53 180.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Ank PF00023.25 KFM06534.1 - 3.4e-06 26.5 0.0 0.00018 21.1 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 KFM06534.1 - 6.8e-06 26.3 0.0 6.8e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFM06534.1 - 2.1e-05 24.9 0.0 4e-05 24.0 0.0 1.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM06534.1 - 0.00017 21.4 0.0 0.013 15.6 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 KFM06534.1 - 0.00036 20.6 0.0 0.087 13.1 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) ubiquitin PF00240.18 KFM06535.1 - 1.5e-13 49.9 0.1 2.2e-13 49.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KFM06535.1 - 7.4e-05 22.3 0.1 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like MMS19_C PF12460.3 KFM06536.1 - 2.2e-116 388.9 11.8 3.3e-116 388.4 0.8 3.8 3 1 1 4 4 4 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.1 KFM06536.1 - 2.1e-98 328.7 1.1 3.1e-97 324.9 0.0 3.2 3 0 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.1 KFM06536.1 - 1.8e-08 34.5 11.4 0.001 19.3 0.5 5.8 4 3 2 6 6 6 4 HEAT repeats MIF4G PF02854.14 KFM06536.1 - 0.012 15.0 0.0 0.038 13.3 0.0 1.8 1 0 0 1 1 1 0 MIF4G domain ParcG PF10274.4 KFM06536.1 - 0.16 11.9 0.9 4.9 7.0 0.0 3.0 3 0 0 3 3 3 0 Parkin co-regulated protein zf-DHHC PF01529.15 KFM06537.1 - 8.2e-32 109.9 13.8 8.2e-32 109.9 9.5 2.3 1 1 1 2 2 2 1 DHHC palmitoyltransferase Cytochrom_B_N PF00033.14 KFM06537.1 - 0.00045 19.6 8.7 0.23 10.7 0.1 2.3 2 0 0 2 2 2 2 Cytochrome b(N-terminal)/b6/petB EXOSC1 PF10447.4 KFM06538.1 - 2.8e-26 91.2 0.1 4.8e-26 90.5 0.1 1.4 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 S1 PF00575.18 KFM06538.1 - 0.033 14.2 0.2 0.3 11.1 0.1 2.1 1 1 0 1 1 1 0 S1 RNA binding domain His_Phos_1 PF00300.17 KFM06539.1 - 4.5e-24 85.3 0.0 6.1e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) NUC173 PF08161.7 KFM06540.1 - 1.2e-75 253.2 0.0 7.3e-72 240.8 0.0 3.4 4 0 0 4 4 4 2 NUC173 domain HEAT PF02985.17 KFM06540.1 - 0.0081 16.1 0.8 4 7.7 0.1 4.1 3 0 0 3 3 3 1 HEAT repeat DUF3136 PF11334.3 KFM06540.1 - 0.012 14.9 0.1 3.8 7.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3136) PGA2 PF07543.7 KFM06540.1 - 0.88 9.3 17.1 0.49 10.1 5.3 2.5 2 0 0 2 2 2 0 Protein trafficking PGA2 RhoGAP PF00620.22 KFM06541.1 - 1.4e-35 122.1 0.5 1.4e-35 122.1 0.4 1.8 2 0 0 2 2 2 1 RhoGAP domain LRR_8 PF13855.1 KFM06542.1 - 2.8e-93 305.6 89.1 1.2e-13 50.6 1.7 10.0 4 4 7 11 11 11 11 Leucine rich repeat LRR_4 PF12799.2 KFM06542.1 - 1.1e-56 187.6 46.4 1.2e-07 31.1 1.0 10.9 7 2 3 11 11 11 11 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFM06542.1 - 7.7e-35 119.4 8.2 2e-09 37.2 0.1 5.3 5 1 0 5 5 4 4 Leucine rich repeats (6 copies) LRR_1 PF00560.28 KFM06542.1 - 9.8e-30 98.0 47.1 0.0098 15.8 0.0 18.6 20 0 0 20 20 19 9 Leucine Rich Repeat EGF PF00008.22 KFM06542.1 - 2.9e-23 81.4 82.3 1.3e-07 31.4 4.3 7.7 8 0 0 8 8 6 5 EGF-like domain LRRNT PF01462.13 KFM06542.1 - 1.1e-22 78.8 31.0 1.3e-08 34.0 1.1 5.7 4 0 0 4 4 4 3 Leucine rich repeat N-terminal domain Laminin_G_2 PF02210.19 KFM06542.1 - 1.3e-21 76.9 0.1 2.3e-21 76.1 0.1 1.4 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.18 KFM06542.1 - 3.5e-21 75.5 0.0 5.7e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain LRRCT PF01463.19 KFM06542.1 - 9.6e-17 59.4 11.1 0.003 17.6 0.3 7.6 5 0 0 5 5 5 4 Leucine rich repeat C-terminal domain LRR_9 PF14580.1 KFM06542.1 - 1.6e-13 50.6 13.2 0.002 17.7 0.1 5.4 4 1 1 5 5 5 5 Leucine-rich repeat LRR_6 PF13516.1 KFM06542.1 - 2e-09 36.5 48.8 2.1 8.6 0.0 16.6 15 2 1 16 16 16 3 Leucine Rich repeat LRR_7 PF13504.1 KFM06542.1 - 3.3e-06 26.3 55.8 2.1 8.9 0.1 16.0 16 0 0 16 16 16 2 Leucine rich repeat hEGF PF12661.2 KFM06542.1 - 0.00041 20.2 65.8 0.024 14.6 2.0 8.9 9 0 0 9 9 8 5 Human growth factor-like EGF Laminin_G_3 PF13385.1 KFM06542.1 - 0.0012 19.1 0.3 0.0024 18.1 0.2 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily EGF_CA PF07645.10 KFM06542.1 - 0.0014 18.5 7.5 0.0014 18.5 5.2 8.4 7 1 2 9 9 7 1 Calcium-binding EGF domain DUF4553 PF15090.1 KFM06543.1 - 1.4e-164 548.4 44.7 1.4e-164 548.4 31.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4553) HTH_psq PF05225.11 KFM06544.1 - 2.3e-15 55.8 0.3 1.3e-14 53.4 0.0 2.2 2 0 0 2 2 2 1 helix-turn-helix, Psq domain RRM_1 PF00076.17 KFM06545.1 - 4.1e-09 35.9 0.0 8.1e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM06545.1 - 9.2e-07 28.7 0.0 1.8e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM06545.1 - 3.1e-05 23.7 0.0 5.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LIM_bind PF01803.11 KFM06547.1 - 1.9e-72 243.2 2.9 6e-72 241.6 2.0 1.8 1 1 0 1 1 1 1 LIM-domain binding protein Prominin PF05478.6 KFM06548.1 - 3.3e-09 34.8 0.0 3.7e-09 34.7 0.0 1.0 1 0 0 1 1 1 1 Prominin Fib_alpha PF08702.5 KFM06548.1 - 0.14 12.2 0.1 0.33 11.0 0.0 1.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Prominin PF05478.6 KFM06549.1 - 6.1e-111 371.3 0.0 6.9e-111 371.2 0.0 1.0 1 0 0 1 1 1 1 Prominin Baculo_PEP_C PF04513.7 KFM06549.1 - 0.0066 16.2 2.5 0.0066 16.2 1.7 1.8 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus KfrA_N PF11740.3 KFM06549.1 - 0.034 14.5 6.5 0.056 13.8 4.5 1.3 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term AAA_32 PF13654.1 KFM06549.1 - 0.046 12.3 2.4 0.061 11.9 1.7 1.1 1 0 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.10 KFM06549.1 - 0.21 10.7 2.2 0.29 10.3 1.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FUSC PF04632.7 KFM06549.1 - 0.44 8.9 2.7 0.71 8.2 1.9 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2682 PF10909.3 KFM06549.1 - 2 8.7 6.6 1.2 9.5 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2682) DUF1741 PF08427.5 KFM06551.1 - 1.8e-86 289.4 6.6 1.8e-86 289.4 4.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) EF-hand_7 PF13499.1 KFM06552.1 - 2.6e-23 81.9 1.5 5.4e-15 55.2 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KFM06552.1 - 4.8e-22 75.5 8.8 2.3e-07 29.5 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 KFM06552.1 - 3.5e-19 66.8 4.0 5.9e-06 25.7 0.0 4.2 4 1 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 KFM06552.1 - 4.4e-17 60.5 3.2 4.8e-05 22.5 0.0 3.8 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 KFM06552.1 - 2.7e-15 55.6 7.6 9.8e-08 31.5 0.2 3.7 3 2 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFM06552.1 - 2.5e-06 27.4 1.3 0.00014 21.9 0.1 3.0 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFM06552.1 - 0.00029 20.5 2.4 0.032 13.9 0.1 2.8 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand S10_plectin PF03501.10 KFM06552.1 - 0.034 13.9 0.0 0.12 12.2 0.0 1.9 1 1 0 1 1 1 0 Plectin/S10 domain EF-hand_9 PF14658.1 KFM06552.1 - 0.041 13.7 0.3 2.6 8.0 0.0 3.2 2 1 1 3 3 3 0 EF-hand domain EF-hand_2 PF09068.6 KFM06552.1 - 0.13 12.3 1.9 21 5.1 0.0 3.0 2 1 0 3 3 3 0 EF hand Nucleoplasmin PF03066.10 KFM06553.1 - 1.1e-44 151.5 0.1 1.2e-44 151.4 0.1 1.0 1 0 0 1 1 1 1 Nucleoplasmin Nitrophorin PF02087.10 KFM06553.1 - 0.00086 19.1 0.1 0.0011 18.8 0.1 1.2 1 0 0 1 1 1 1 Nitrophorin FGF PF00167.13 KFM06554.1 - 7.9e-39 132.1 1.0 1.2e-38 131.6 0.7 1.2 1 0 0 1 1 1 1 Fibroblast growth factor BPL_C PF02237.12 KFM06554.1 - 0.041 13.5 0.1 0.095 12.3 0.1 1.7 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain WD40 PF00400.27 KFM06555.1 - 2.6e-20 71.4 16.0 1.6e-08 34.0 0.0 6.5 5 1 0 5 5 5 5 WD domain, G-beta repeat DPCD PF14913.1 KFM06556.1 - 7e-94 312.4 0.2 8.1e-94 312.2 0.1 1.0 1 0 0 1 1 1 1 DPCD protein family MucBP PF06458.7 KFM06556.1 - 0.018 15.6 0.2 0.2 12.3 0.0 2.1 2 0 0 2 2 2 0 MucBP domain CBM_21 PF03370.8 KFM06556.1 - 0.11 12.4 0.1 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative phosphatase regulatory subunit HHH_8 PF14716.1 KFM06557.1 - 2.9e-10 40.1 0.0 5.6e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain zf-LYAR PF08790.6 KFM06557.1 - 0.053 13.2 0.4 0.11 12.2 0.3 1.4 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger Sugar_tr PF00083.19 KFM06558.1 - 6e-102 341.5 22.7 6.7e-102 341.3 15.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFM06558.1 - 1.2e-12 47.2 38.9 1.2e-08 34.1 8.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.27 KFM06559.1 - 1e-59 196.3 16.0 4e-10 39.1 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Beta-TrCP_D PF12125.3 KFM06559.1 - 2.7e-27 94.0 3.9 4.7e-27 93.3 2.7 1.4 1 0 0 1 1 1 1 D domain of beta-TrCP F-box-like PF12937.2 KFM06559.1 - 1.5e-10 40.6 0.6 4.4e-10 39.1 0.1 2.0 1 1 1 2 2 2 1 F-box-like F-box PF00646.28 KFM06559.1 - 8.6e-08 31.6 0.0 2.3e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 F-box domain Nucleoporin_N PF08801.6 KFM06559.1 - 1.4e-06 27.3 1.8 0.047 12.4 0.0 3.8 1 1 2 3 3 3 2 Nup133 N terminal like Nup160 PF11715.3 KFM06559.1 - 0.00073 17.7 9.2 0.92 7.5 0.1 4.6 1 1 4 5 5 5 4 Nucleoporin Nup120/160 DUF4508 PF14969.1 KFM06559.1 - 0.02 14.8 0.1 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) Cellulase-like PF12876.2 KFM06559.1 - 0.092 13.2 0.0 0.79 10.2 0.0 2.6 3 0 0 3 3 3 0 Sugar-binding cellulase-like Homeobox PF00046.24 KFM06560.1 - 4.5e-21 74.2 6.6 8.2e-21 73.3 4.6 1.4 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 KFM06560.1 - 0.0023 16.9 0.2 0.0041 16.1 0.1 1.4 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez A_deaminase_N PF08451.6 KFM06560.1 - 0.048 13.6 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 Adenosine/AMP deaminase N-terminal I-set PF07679.11 KFM06561.1 - 6.5e-14 51.5 0.0 9.4e-14 51.0 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Kazal_1 PF00050.16 KFM06561.1 - 4.8e-07 29.6 1.1 4.8e-07 29.6 0.7 2.5 1 1 1 2 2 2 1 Kazal-type serine protease inhibitor domain Ig_2 PF13895.1 KFM06561.1 - 1.7e-06 28.0 0.0 3.6e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFM06561.1 - 2.7e-05 24.2 0.0 0.00012 22.1 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin domain Kazal_2 PF07648.10 KFM06561.1 - 8e-05 22.4 7.5 8.9e-05 22.3 0.5 2.6 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain IGFBP PF00219.13 KFM06561.1 - 0.00011 22.6 20.7 0.00011 22.6 14.3 2.1 2 0 0 2 2 2 1 Insulin-like growth factor binding protein V-set PF07686.12 KFM06561.1 - 0.00095 19.0 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.1 KFM06561.1 - 0.0072 16.8 0.0 0.014 15.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Mtc PF03820.12 KFM06562.1 - 1.4e-131 437.7 0.0 1.6e-131 437.5 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier PDZ PF00595.19 KFM06563.1 - 9.6e-37 125.0 1.2 1.4e-17 63.6 0.2 2.3 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM06563.1 - 4.6e-13 48.8 0.1 3.3e-05 23.7 0.0 2.4 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.1 KFM06563.1 - 0.014 15.1 0.4 1.6 8.5 0.0 2.6 2 0 0 2 2 2 0 Tricorn protease PDZ domain THF_DHG_CYH PF00763.18 KFM06563.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain PDZ PF00595.19 KFM06564.1 - 5.3e-12 45.7 0.2 5.6e-12 45.6 0.2 1.1 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM06564.1 - 0.0066 16.3 0.0 0.007 16.2 0.0 1.2 1 0 0 1 1 1 1 PDZ domain DUF1180 PF06679.7 KFM06565.1 - 2.2 8.1 4.4 2.5 7.9 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) AAA_25 PF13481.1 KFM06566.1 - 1.5e-09 37.5 0.0 3e-09 36.5 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFM06566.1 - 7.6e-05 22.7 0.0 0.00018 21.5 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 KFM06566.1 - 8.7e-05 21.9 0.0 0.00026 20.4 0.0 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.1 KFM06566.1 - 0.00018 21.8 0.0 0.00027 21.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KFM06566.1 - 0.00024 20.1 0.0 0.0003 19.7 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 KFM06566.1 - 0.001 19.2 0.0 0.0019 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KFM06566.1 - 0.0015 17.7 0.0 0.0022 17.1 0.0 1.2 1 0 0 1 1 1 1 KaiC AAA_33 PF13671.1 KFM06566.1 - 0.0041 16.9 0.0 0.0082 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 KFM06566.1 - 0.0071 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 KFM06566.1 - 0.015 15.0 0.0 0.029 14.0 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain DnaB_C PF03796.10 KFM06566.1 - 0.015 14.1 0.0 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_17 PF13207.1 KFM06566.1 - 0.016 16.0 0.0 0.05 14.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KFM06566.1 - 0.027 14.1 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 KFM06566.1 - 0.032 14.5 0.1 0.056 13.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter MobB PF03205.9 KFM06566.1 - 0.033 13.8 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 KFM06566.1 - 0.04 13.3 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.11 KFM06566.1 - 0.06 12.5 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein cobW PF02492.14 KFM06566.1 - 0.072 12.5 0.1 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 KFM06566.1 - 0.075 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 KFM06566.1 - 0.086 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_14 PF13173.1 KFM06566.1 - 0.091 12.6 0.0 0.22 11.4 0.0 1.6 1 1 1 2 2 2 0 AAA domain MutS_V PF00488.16 KFM06566.1 - 0.14 11.4 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 MutS domain V FAM178 PF14816.1 KFM06568.1 - 1.2e-165 550.8 9.3 1.6e-165 550.3 6.4 1.1 1 0 0 1 1 1 1 Family of unknown function, FAM178 Di19_C PF14571.1 KFM06569.1 - 0.24 11.6 0.1 0.24 11.6 0.1 2.5 3 0 0 3 3 3 0 Stress-induced protein Di19, C-terminal DUF605 PF04652.11 KFM06569.1 - 4.8 6.4 9.6 5.7 6.2 6.7 1.1 1 0 0 1 1 1 0 Vta1 like MFS_2 PF13347.1 KFM06571.1 - 1.8e-23 82.6 11.3 4.4e-23 81.3 7.9 1.6 1 1 0 1 1 1 1 MFS/sugar transport protein Actin PF00022.14 KFM06572.1 - 8.6e-83 277.9 0.0 9.7e-83 277.7 0.0 1.0 1 0 0 1 1 1 1 Actin DUF4188 PF13826.1 KFM06572.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4188) SUFU_C PF12470.3 KFM06573.1 - 1.5e-95 318.6 0.0 1.9e-95 318.3 0.0 1.1 1 0 0 1 1 1 1 Suppressor of Fused Gli/Ci N terminal binding domain SUFU PF05076.8 KFM06573.1 - 7.9e-36 123.1 0.0 1.2e-35 122.5 0.0 1.3 1 0 0 1 1 1 1 Suppressor of fused protein (SUFU) zf-C3HC4_4 PF15227.1 KFM06574.1 - 3.6e-11 42.7 8.3 3.6e-11 42.7 5.7 3.3 4 0 0 4 4 3 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KFM06574.1 - 1.2e-09 37.6 6.5 1.2e-09 37.6 4.5 2.8 3 1 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM06574.1 - 1.4e-07 31.4 8.9 1.4e-07 31.4 6.1 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM06574.1 - 9.4e-07 28.5 8.1 9.4e-07 28.5 5.6 3.3 3 0 0 3 3 2 1 Ring finger domain CASP_C PF08172.7 KFM06574.1 - 1.7e-05 24.0 2.6 3.1e-05 23.1 1.8 1.5 1 0 0 1 1 1 1 CASP C terminal zf-RING_UBOX PF13445.1 KFM06574.1 - 2.7e-05 23.7 4.6 2.7e-05 23.7 3.2 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-B_box PF00643.19 KFM06574.1 - 0.00026 20.7 7.7 0.00026 20.7 5.3 5.2 5 1 0 5 5 4 1 B-box zinc finger zf-RING_5 PF14634.1 KFM06574.1 - 0.00086 18.9 6.6 0.00086 18.9 4.6 3.9 3 2 1 4 4 3 1 zinc-RING finger domain zf-RING_6 PF14835.1 KFM06574.1 - 0.018 14.8 3.5 0.067 12.9 2.4 2.0 1 0 0 1 1 1 0 zf-RING of BARD1-type protein U-box PF04564.10 KFM06574.1 - 0.093 12.7 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 U-box domain IncA PF04156.9 KFM06574.1 - 0.57 9.7 11.6 1.1 8.8 8.0 1.4 1 0 0 1 1 1 0 IncA protein Phasin PF05597.6 KFM06574.1 - 0.61 9.8 8.4 1.1 9.0 5.8 1.3 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) APG6 PF04111.7 KFM06574.1 - 1.5 7.8 12.6 2.3 7.1 8.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 KFM06574.1 - 4.1 5.7 9.8 5.9 5.1 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Arf PF00025.16 KFM06576.1 - 4e-72 241.1 0.0 4.5e-72 240.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KFM06576.1 - 1.5e-14 53.6 0.0 1.7e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KFM06576.1 - 4.9e-14 51.8 0.8 2.2e-08 33.1 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 KFM06576.1 - 1.5e-13 50.4 0.0 1.7e-13 50.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KFM06576.1 - 2.4e-13 49.8 0.0 2.9e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KFM06576.1 - 5.7e-12 46.1 0.0 7.5e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KFM06576.1 - 9.9e-10 38.4 0.0 1.3e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFM06576.1 - 4e-07 29.6 0.0 7.9e-05 22.1 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA PF00004.24 KFM06576.1 - 0.00011 22.3 0.0 0.00016 21.9 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 KFM06576.1 - 0.00094 18.6 0.0 0.002 17.6 0.0 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 KFM06576.1 - 0.0047 17.7 0.2 0.043 14.6 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 KFM06576.1 - 0.01 15.7 0.1 0.024 14.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KFM06576.1 - 0.016 15.3 0.1 0.19 11.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 KFM06576.1 - 0.025 14.2 0.0 6.1 6.4 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 KFM06576.1 - 0.028 14.7 0.1 0.049 13.9 0.1 1.5 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 KFM06576.1 - 0.03 14.1 0.0 0.52 10.1 0.0 2.1 1 1 0 2 2 2 0 Dynamin family Arch_ATPase PF01637.13 KFM06576.1 - 0.036 13.7 0.1 0.044 13.4 0.0 1.3 1 1 0 1 1 1 0 Archaeal ATPase FeoB_N PF02421.13 KFM06576.1 - 0.062 12.5 0.1 0.18 11.0 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B ArgK PF03308.11 KFM06576.1 - 0.064 12.0 0.1 6.6 5.4 0.0 2.7 2 1 0 2 2 2 0 ArgK protein cobW PF02492.14 KFM06576.1 - 0.075 12.4 0.0 7.7 5.9 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 KFM06576.1 - 0.098 12.3 0.0 0.21 11.2 0.0 1.5 1 1 0 1 1 1 0 NTPase AAA_28 PF13521.1 KFM06576.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KFM06576.1 - 0.12 12.6 0.1 0.21 11.8 0.1 1.7 1 1 0 1 1 1 0 ABC transporter Mtc PF03820.12 KFM06577.1 - 4.2e-125 416.4 0.0 4.7e-125 416.2 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier EmrE PF13536.1 KFM06577.1 - 3.2 7.9 7.5 4.6 7.4 1.1 2.2 2 0 0 2 2 2 0 Multidrug resistance efflux transporter WBP-1 PF11669.3 KFM06578.1 - 7.4e-50 167.2 13.7 1.2e-49 166.6 9.5 1.3 1 0 0 1 1 1 1 WW domain-binding protein 1 p450 PF00067.17 KFM06579.1 - 7.1e-139 463.2 0.0 8e-139 463.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_31 PF13847.1 KFM06580.1 - 1.6e-33 115.4 0.0 2.8e-33 114.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFM06580.1 - 6.6e-19 68.1 0.0 1.5e-18 67.0 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFM06580.1 - 1.9e-15 57.3 0.0 7.7e-15 55.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFM06580.1 - 7.9e-15 54.5 0.0 1.2e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 KFM06580.1 - 4.7e-14 52.4 0.0 6.9e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFM06580.1 - 7.3e-13 48.8 0.0 1.4e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFM06580.1 - 2.3e-12 47.1 0.0 1.7e-11 44.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFM06580.1 - 1.3e-09 38.1 0.0 6.6e-09 35.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 KFM06580.1 - 7.8e-06 25.5 0.0 1.3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.10 KFM06580.1 - 5.3e-05 22.9 0.0 8.7e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.9 KFM06580.1 - 0.00057 19.3 0.0 0.0016 17.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 KFM06580.1 - 0.0033 16.5 0.0 0.0052 15.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_24 PF13578.1 KFM06580.1 - 0.019 15.7 0.0 0.038 14.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_M29 PF02073.10 KFM06580.1 - 0.11 11.2 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Thermophilic metalloprotease (M29) FtsJ PF01728.14 KFM06580.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase DUF21 PF01595.15 KFM06581.1 - 5.9e-28 97.4 0.0 1e-27 96.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 KFM06581.1 - 6.2e-08 32.3 0.1 0.00055 19.6 0.0 2.7 2 0 0 2 2 2 2 CBS domain cNMP_binding PF00027.24 KFM06581.1 - 2.5e-05 23.9 0.0 0.012 15.4 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Nrf1_DNA-bind PF10491.4 KFM06581.1 - 0.099 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 NLS-binding and DNA-binding and dimerisation domains of Nrf1 5_nucleotid PF05761.9 KFM06582.1 - 2.4e-182 606.4 0.2 2.9e-182 606.1 0.1 1.1 1 0 0 1 1 1 1 5' nucleotidase family zf-C3HC4 PF00097.20 KFM06583.1 - 1.1e-08 34.5 11.0 1.9e-08 33.7 7.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM06583.1 - 4.5e-08 32.9 11.5 9.4e-08 31.9 8.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM06583.1 - 8.3e-06 25.5 9.4 8.3e-06 25.5 6.5 1.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFM06583.1 - 4.5e-05 23.0 7.8 8.2e-05 22.1 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM06583.1 - 0.00041 19.9 10.6 0.00041 19.9 7.4 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.1 KFM06583.1 - 0.0029 17.3 2.6 0.005 16.5 1.8 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 KFM06583.1 - 0.017 15.0 10.1 0.037 13.9 7.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KFM06583.1 - 0.041 13.6 6.1 0.083 12.6 4.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Methyltransf_23 PF13489.1 KFM06583.1 - 0.14 11.8 0.0 0.31 10.7 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain C1_3 PF07649.7 KFM06583.1 - 0.2 11.7 8.7 0.3 11.1 3.0 2.6 2 0 0 2 2 2 0 C1-like domain zf-Nse PF11789.3 KFM06583.1 - 0.28 10.7 6.3 0.55 9.7 4.4 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF1272 PF06906.6 KFM06583.1 - 0.39 10.5 5.7 1 9.2 3.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-rbx1 PF12678.2 KFM06583.1 - 1.4 9.0 7.8 3.5 7.8 5.4 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger WD40 PF00400.27 KFM06584.1 - 4.7e-71 232.3 7.9 2.4e-13 49.3 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 KFM06584.1 - 2.6e-42 144.2 6.2 4.2e-42 143.6 4.3 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit Nup160 PF11715.3 KFM06584.1 - 7.7e-09 34.2 1.1 0.028 12.5 0.0 3.8 3 1 1 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.6 KFM06584.1 - 0.0097 15.6 0.0 0.058 13.0 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 KFM06584.1 - 0.024 12.9 0.0 1.3 7.2 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain DUF4144 PF13642.1 KFM06584.1 - 0.22 11.8 1.0 0.5 10.7 0.7 1.5 1 0 0 1 1 1 0 protein structure with unknown function ATP_synth_reg PF14960.1 KFM06585.1 - 1.3e-25 88.3 0.3 1.4e-25 88.1 0.2 1.0 1 0 0 1 1 1 1 ATP synthase regulation DUF4345 PF14248.1 KFM06585.1 - 0.089 12.2 0.0 0.1 12.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4345) Suf PF05843.9 KFM06586.1 - 1.3e-12 48.0 22.5 2.8e-09 37.1 0.6 4.1 2 1 2 4 4 4 3 Suppressor of forked protein (Suf) TPR_19 PF14559.1 KFM06586.1 - 5.2e-12 45.9 0.0 4.6e-06 26.8 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFM06586.1 - 1.4e-10 41.5 0.0 3.3e-05 24.4 0.1 3.6 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFM06586.1 - 3.9e-10 39.4 1.1 0.097 13.3 0.1 4.7 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_15 PF13429.1 KFM06586.1 - 2.2e-08 33.5 6.7 0.00034 19.7 0.7 3.3 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFM06586.1 - 2.8e-07 30.0 0.1 0.0066 16.0 0.3 3.6 3 0 0 3 3 3 2 TPR repeat TPR_12 PF13424.1 KFM06586.1 - 0.00045 20.0 6.2 0.47 10.4 0.0 3.8 1 1 4 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 KFM06586.1 - 0.025 14.7 3.5 0.067 13.3 0.4 2.7 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 KFM06586.1 - 0.033 14.1 6.7 1.6 8.8 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat PTA_PTB PF01515.14 KFM06586.1 - 0.055 12.5 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Phosphate acetyl/butaryl transferase TPR_6 PF13174.1 KFM06586.1 - 1.6 9.3 6.7 17 6.1 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFM06586.1 - 4.5 7.3 7.9 0.77 9.7 0.2 3.8 4 2 1 5 5 4 0 Tetratricopeptide repeat Ca_hom_mod PF14798.1 KFM06587.1 - 6.7e-91 303.7 0.9 8.1e-91 303.4 0.6 1.0 1 0 0 1 1 1 1 Calcium homeostasis modulator DUF1218 PF06749.7 KFM06587.1 - 0.029 14.8 1.9 0.069 13.6 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) DUF996 PF06195.8 KFM06587.1 - 0.035 14.0 0.2 0.32 10.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF996) Ca_hom_mod PF14798.1 KFM06588.1 - 1.3e-83 279.8 12.2 1.5e-83 279.6 8.5 1.0 1 0 0 1 1 1 1 Calcium homeostasis modulator Neuralized PF07177.7 KFM06589.1 - 2e-48 162.0 0.2 1.1e-31 108.4 0.0 2.5 2 0 0 2 2 2 2 Neuralized zf-C3HC4_3 PF13920.1 KFM06589.1 - 1.5e-12 46.9 13.0 1.5e-12 46.9 9.0 2.9 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM06589.1 - 1.4e-06 28.1 16.6 1.4e-06 28.1 11.5 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF3049 PF11250.3 KFM06590.1 - 0.088 12.5 0.5 0.87 9.3 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3049) SH3_1 PF00018.23 KFM06591.1 - 6.5e-37 124.6 20.2 3.9e-11 42.1 0.2 5.4 5 0 0 5 5 5 5 SH3 domain SH3_2 PF07653.12 KFM06591.1 - 3.7e-34 115.9 10.8 5.6e-11 41.7 0.1 5.3 5 0 0 5 5 5 5 Variant SH3 domain SH3_9 PF14604.1 KFM06591.1 - 1.3e-31 107.9 17.8 5.4e-10 38.7 0.1 5.4 5 0 0 5 5 5 5 Variant SH3 domain SH3_3 PF08239.6 KFM06591.1 - 3.2e-15 56.0 24.1 0.00099 19.2 0.1 5.5 5 0 0 5 5 5 5 Bacterial SH3 domain SH3_6 PF12913.2 KFM06591.1 - 0.16 11.2 2.4 0.74 9.0 0.1 2.8 2 0 0 2 2 2 0 SH3 domain of the SH3b1 type KGK PF08872.5 KFM06591.1 - 0.42 10.7 4.8 31 4.7 0.0 3.8 4 0 0 4 4 4 0 KGK domain SH3_4 PF06347.8 KFM06591.1 - 1.3 8.6 21.2 0.16 11.5 0.4 4.5 5 0 0 5 5 5 0 Bacterial SH3 domain PX PF00787.19 KFM06592.1 - 4.8e-17 61.7 0.1 5.4e-17 61.6 0.1 1.0 1 0 0 1 1 1 1 PX domain STN1_2 PF09170.5 KFM06593.1 - 9.9e-58 194.7 2.3 2.4e-57 193.5 1.6 1.7 1 1 0 1 1 1 1 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 tRNA_anti-codon PF01336.20 KFM06593.1 - 3.3e-09 36.4 0.1 7e-09 35.4 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Stn1 PF10451.4 KFM06593.1 - 6.9e-09 34.9 2.4 1.4e-07 30.6 0.1 2.9 2 1 0 3 3 3 1 Telomere regulation protein Stn1 tRNA_anti_2 PF13742.1 KFM06593.1 - 0.097 12.5 0.1 0.3 10.9 0.0 1.8 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain PKK PF12474.3 KFM06594.1 - 8.3e-70 233.0 98.7 1.4e-44 151.2 29.0 7.8 6 2 1 8 8 8 2 Polo kinase kinase Pkinase PF00069.20 KFM06594.1 - 1.3e-69 234.2 0.0 1.3e-69 234.2 0.0 4.3 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM06594.1 - 4.3e-48 163.6 0.0 4.3e-48 163.6 0.0 2.8 3 0 0 3 3 3 1 Protein tyrosine kinase Collagen PF01391.13 KFM06595.1 - 3.4e-62 205.8 393.7 1.1e-09 37.7 23.4 17.8 9 4 6 15 15 15 14 Collagen triple helix repeat (20 copies) Mei5 PF10376.4 KFM06596.1 - 1.4e-38 132.6 11.6 3.4e-38 131.3 8.0 1.5 1 1 0 1 1 1 1 Double-strand recombination repair protein WD40 PF00400.27 KFM06597.1 - 0.052 13.4 0.1 1.5 8.8 0.0 3.0 3 0 0 3 3 3 0 WD domain, G-beta repeat GST_N_3 PF13417.1 KFM06600.1 - 1.1e-23 83.2 0.0 2.4e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFM06600.1 - 8.5e-17 60.9 0.0 1.7e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFM06600.1 - 3.1e-10 39.9 0.1 4.8e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KFM06600.1 - 6.8e-08 32.5 0.0 1.2e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFM06600.1 - 1.6e-07 31.1 0.0 2.3e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFM06600.1 - 2e-05 24.9 0.0 3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 KFM06600.1 - 0.0013 18.6 0.0 0.0029 17.5 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin Mab-21 PF03281.9 KFM06601.1 - 1e-22 80.6 4.3 1.1e-20 73.9 3.0 2.3 1 1 0 1 1 1 1 Mab-21 protein CemA PF03040.9 KFM06601.1 - 0.053 13.1 1.1 0.1 12.2 0.8 1.4 1 0 0 1 1 1 0 CemA family DUF904 PF06005.7 KFM06602.1 - 0.018 15.3 9.7 0.018 15.3 6.7 13.3 5 2 2 7 7 7 0 Protein of unknown function (DUF904) PKD PF00801.15 KFM06603.1 - 3e-11 42.8 1.6 1.1e-05 25.1 0.0 2.6 2 0 0 2 2 2 2 PKD domain BNR PF02012.15 KFM06603.1 - 0.13 12.1 21.0 2.5 8.2 0.3 6.3 7 0 0 7 7 7 0 BNR/Asp-box repeat PKD PF00801.15 KFM06604.1 - 1e-11 44.4 4.1 1.8e-07 30.8 0.0 2.6 2 0 0 2 2 2 2 PKD domain BNR PF02012.15 KFM06604.1 - 0.00072 19.0 11.5 3.9 7.7 0.1 5.7 5 0 0 5 5 5 2 BNR/Asp-box repeat BNR_2 PF13088.1 KFM06604.1 - 0.092 12.0 0.0 3.8 6.7 0.0 2.9 2 1 0 2 2 2 0 BNR repeat-like domain RVT_1 PF00078.22 KFM06605.1 - 0.041 13.2 0.0 0.07 12.4 0.0 1.4 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_M24 PF00557.19 KFM06606.1 - 1.1e-42 145.9 0.0 1.6e-42 145.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 KFM06606.1 - 1.1e-18 68.0 0.0 9.4e-16 58.5 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Aldolase_II PF00596.16 KFM06608.1 - 1.3e-37 129.1 0.1 2.1e-37 128.5 0.0 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF16 PF01519.11 KFM06608.1 - 0.02 15.0 3.3 0.074 13.2 2.3 2.0 1 1 0 1 1 1 0 Protein of unknown function DUF16 Lge1 PF11488.3 KFM06608.1 - 0.055 13.6 3.7 0.64 10.2 0.3 3.0 3 0 0 3 3 3 0 Transcriptional regulatory protein LGE1 HLH PF00010.21 KFM06609.1 - 2.9e-12 46.0 1.0 1.8e-10 40.3 0.7 2.5 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain APG6 PF04111.7 KFM06609.1 - 0.0065 15.5 2.8 0.0083 15.2 1.9 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 IncA PF04156.9 KFM06609.1 - 0.033 13.8 2.4 0.041 13.4 1.7 1.3 1 0 0 1 1 1 0 IncA protein DUF3450 PF11932.3 KFM06609.1 - 0.044 13.0 0.1 0.052 12.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DivIC PF04977.10 KFM06609.1 - 0.3 10.6 3.3 0.7 9.4 2.3 1.6 1 0 0 1 1 1 0 Septum formation initiator Uds1 PF15456.1 KFM06609.1 - 0.57 10.1 7.7 0.056 13.4 1.3 2.0 2 1 0 2 2 2 0 Up-regulated During Septation EMP24_GP25L PF01105.19 KFM06609.1 - 4.2 7.0 5.6 0.62 9.7 0.8 1.7 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD SMN PF06003.7 KFM06610.1 - 6.8e-17 61.4 4.3 1.4e-16 60.4 2.9 1.7 1 1 0 1 1 1 1 Survival motor neuron protein (SMN) TUDOR PF00567.19 KFM06610.1 - 6.1e-05 22.8 0.0 0.00022 21.0 0.0 2.0 1 1 1 2 2 2 1 Tudor domain DUF3703 PF12487.3 KFM06610.1 - 0.24 11.0 1.9 0.31 10.6 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3703) EAP30 PF04157.11 KFM06610.1 - 0.81 8.7 5.7 7.6 5.6 0.9 2.2 2 0 0 2 2 2 0 EAP30/Vps36 family DSPc PF00782.15 KFM06611.1 - 8e-45 151.6 0.1 1.1e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFM06611.1 - 1.3e-06 27.9 0.0 1.7e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 KFM06611.1 - 0.063 12.7 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 KFM06611.1 - 0.064 13.2 0.0 0.085 12.9 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate SMC_N PF02463.14 KFM06612.1 - 9.7e-62 208.0 27.4 1.9e-61 207.0 19.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KFM06612.1 - 7.1e-24 84.0 0.0 2e-23 82.6 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KFM06612.1 - 2.5e-11 44.0 0.1 5.4e-07 29.8 0.1 4.6 2 2 1 4 4 4 2 AAA domain AAA_23 PF13476.1 KFM06612.1 - 2.1e-07 31.4 49.5 2.1e-07 31.4 34.3 7.4 2 2 3 5 5 5 1 AAA domain AAA_29 PF13555.1 KFM06612.1 - 0.00053 19.4 0.0 0.0012 18.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KFM06612.1 - 0.22 10.9 0.0 0.22 10.9 0.0 3.2 3 1 0 3 3 3 0 FtsK/SpoIIIE family AAA_13 PF13166.1 KFM06612.1 - 0.32 9.4 0.0 0.32 9.4 0.0 6.0 3 2 3 6 6 6 0 AAA domain ABC_tran PF00005.22 KFM06612.1 - 1.2 9.4 0.0 1.2 9.4 0.0 7.1 2 2 2 4 4 4 0 ABC transporter Reo_sigmaC PF04582.7 KFM06612.1 - 4.6 6.3 24.6 3.8 6.5 0.2 4.4 3 1 1 4 4 4 0 Reovirus sigma C capsid protein RRM_5 PF13893.1 KFM06613.1 - 1.3e-09 37.7 0.0 2.3e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM06613.1 - 1.1e-07 31.7 0.0 2.3e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_jaz PF12171.3 KFM06613.1 - 0.00074 19.5 0.1 0.0018 18.3 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM06613.1 - 0.078 13.2 0.5 0.36 11.0 0.2 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type RRM_1 PF00076.17 KFM06613.1 - 0.091 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_jaz PF12171.3 KFM06614.1 - 0.0023 18.0 1.3 0.0038 17.3 0.9 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.7 KFM06614.1 - 0.01 15.3 2.6 0.016 14.7 1.8 1.3 1 0 0 1 1 1 0 U1 zinc finger AKAP95 PF04988.7 KFM06614.1 - 0.034 13.9 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) MA3 PF02847.12 KFM06615.1 - 3.9e-51 171.5 0.4 3.9e-25 87.7 0.3 2.1 2 0 0 2 2 2 2 MA3 domain HABP4_PAI-RBP1 PF04774.10 KFM06615.1 - 0.015 15.7 0.1 0.015 15.7 0.0 2.0 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family LRR_4 PF12799.2 KFM06616.1 - 3.3e-64 211.6 85.6 1.4e-09 37.3 4.4 11.5 5 3 7 13 13 13 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM06616.1 - 2.2e-55 184.2 115.8 4.2e-11 42.4 4.1 9.7 3 2 9 12 12 12 12 Leucine rich repeat LRR_1 PF00560.28 KFM06616.1 - 4.3e-41 132.5 65.2 0.17 12.0 0.0 19.6 20 0 0 20 20 20 16 Leucine Rich Repeat LRR_7 PF13504.1 KFM06616.1 - 3.8e-21 71.4 74.0 0.62 10.4 0.1 18.8 19 0 0 19 19 19 8 Leucine rich repeat LRR_9 PF14580.1 KFM06616.1 - 0.00082 18.9 27.8 0.24 10.9 2.2 5.2 1 1 5 6 6 6 5 Leucine-rich repeat LRR_6 PF13516.1 KFM06616.1 - 0.15 12.2 72.0 13 6.2 0.1 16.7 14 5 4 18 18 18 0 Leucine Rich repeat 7tm_1 PF00001.16 KFM06617.1 - 8.6e-83 277.3 0.0 1.2e-82 276.9 0.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM06617.1 - 1.5e-10 40.6 12.1 9.8e-07 28.1 3.0 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM06617.1 - 4.9e-06 25.8 16.2 1.8e-05 24.0 6.2 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx T2SM PF04612.7 KFM06617.1 - 0.033 13.9 0.1 0.076 12.8 0.0 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Acyltransferase PF01553.16 KFM06618.1 - 3.2e-22 78.3 0.0 9e-22 76.9 0.0 1.8 1 0 0 1 1 1 1 Acyltransferase Zona_pellucida PF00100.18 KFM06619.1 - 2e-40 138.9 6.8 2.4e-40 138.6 4.7 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain AMP-binding PF00501.23 KFM06620.1 - 9e-103 343.8 0.0 1.2e-102 343.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFM06620.1 - 0.049 14.5 0.1 0.98 10.4 0.0 2.4 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain zf-DHHC PF01529.15 KFM06621.1 - 6e-35 120.1 8.8 8.1e-35 119.7 6.1 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase SH3_2 PF07653.12 KFM06621.1 - 2.4e-09 36.5 0.3 8.4e-09 34.7 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 KFM06621.1 - 0.0082 15.7 0.0 0.021 14.4 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain GSAP-16 PF14959.1 KFM06621.1 - 0.13 11.9 0.0 0.38 10.5 0.0 1.7 2 0 0 2 2 2 0 gamma-Secretase-activating protein C-term V-SNARE PF05008.10 KFM06622.1 - 1.7e-19 69.7 3.9 1.7e-19 69.7 2.7 2.1 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 KFM06622.1 - 4.9e-13 48.9 5.7 3.2e-12 46.3 2.3 2.5 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Peptidase_S46 PF10459.4 KFM06622.1 - 0.069 11.5 4.8 0.077 11.4 3.3 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF3198 PF11433.3 KFM06622.1 - 0.26 11.1 1.4 0.99 9.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3198) ApoLp-III PF07464.6 KFM06622.1 - 0.38 10.7 4.3 0.64 10.0 0.4 2.0 1 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF4162 PF13732.1 KFM06622.1 - 0.58 10.7 2.4 0.43 11.1 0.4 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4162) Pox_A_type_inc PF04508.7 KFM06622.1 - 0.79 9.6 0.1 0.79 9.6 0.1 3.2 3 1 0 3 3 3 0 Viral A-type inclusion protein repeat FlaC_arch PF05377.6 KFM06622.1 - 6.2 6.7 7.4 1.1 9.2 1.4 2.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Mnd1 PF03962.10 KFM06622.1 - 8.3 6.0 10.1 65 3.1 7.0 1.9 1 1 0 1 1 1 0 Mnd1 family CTNNB1_binding PF08347.6 KFM06623.1 - 2.6e-36 125.7 9.9 2.6e-36 125.7 6.9 2.8 2 1 0 2 2 2 1 N-terminal CTNNB1 binding HMG_box PF00505.14 KFM06623.1 - 4e-22 78.2 1.0 7.7e-22 77.3 0.7 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFM06623.1 - 7.7e-08 32.5 1.5 1.6e-07 31.5 1.1 1.5 1 0 0 1 1 1 1 HMG-box domain MAT_Alpha1 PF04769.7 KFM06623.1 - 0.085 12.1 0.1 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 Trypsin PF00089.21 KFM06624.1 - 6.1e-67 225.4 0.3 7.9e-67 225.0 0.2 1.2 1 0 0 1 1 1 1 Trypsin Kringle PF00051.13 KFM06624.1 - 9.5e-22 76.9 4.0 2.8e-21 75.3 2.8 1.9 1 0 0 1 1 1 1 Kringle domain EGF PF00008.22 KFM06624.1 - 2.8e-13 49.5 22.3 4.7e-08 32.8 4.1 4.9 5 0 0 5 5 5 2 EGF-like domain Trypsin_2 PF13365.1 KFM06624.1 - 0.0017 18.3 0.0 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain EGF_2 PF07974.8 KFM06624.1 - 0.0055 16.8 25.0 0.013 15.6 7.2 5.0 5 0 0 5 5 5 2 EGF-like domain DUF1986 PF09342.6 KFM06624.1 - 0.011 15.0 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Nebulin PF00880.13 KFM06625.1 - 6.3e-246 783.6 154.1 2.8e-09 36.1 0.2 43.6 43 0 0 43 43 43 43 Nebulin repeat LIM PF00412.17 KFM06625.1 - 6.3e-11 42.1 9.2 1.9e-10 40.6 6.4 1.9 1 0 0 1 1 1 1 LIM domain TPR_MLP1_2 PF07926.7 KFM06627.1 - 1.5e-05 24.7 23.1 1.5e-05 24.7 16.0 8.8 3 1 7 10 10 10 5 TPR/MLP1/MLP2-like protein DivIVA PF05103.8 KFM06627.1 - 0.0016 18.5 17.0 0.0016 18.5 11.8 9.6 4 1 4 8 8 8 2 DivIVA protein IncA PF04156.9 KFM06627.1 - 0.003 17.1 31.0 0.003 17.1 21.5 8.7 2 1 4 6 6 6 2 IncA protein Reo_sigmaC PF04582.7 KFM06627.1 - 3.8 6.6 30.5 0.21 10.7 0.9 4.6 2 1 2 4 4 4 0 Reovirus sigma C capsid protein TUDOR PF00567.19 KFM06628.1 - 2e-121 398.9 5.4 5.1e-34 116.7 0.0 4.6 4 0 0 4 4 4 4 Tudor domain SMN PF06003.7 KFM06628.1 - 1.7e-16 60.1 0.2 7.6e-05 21.9 0.0 4.3 4 0 0 4 4 4 4 Survival motor neuron protein (SMN) zf-MYND PF01753.13 KFM06628.1 - 6.4e-11 41.9 14.0 6.4e-11 41.9 9.7 2.8 2 0 0 2 2 2 1 MYND finger DUF4537 PF15057.1 KFM06628.1 - 6.9e-06 25.8 0.0 2.4 7.9 0.0 3.9 4 0 0 4 4 4 3 Domain of unknown function (DUF4537) Agenet PF05641.7 KFM06628.1 - 3.4e-05 23.9 0.1 1.8 8.7 0.0 4.1 3 0 0 3 3 3 2 Agenet domain SNase PF00565.12 KFM06628.1 - 0.0033 17.6 0.0 0.051 13.8 0.0 2.4 2 0 0 2 2 2 1 Staphylococcal nuclease homologue VWA PF00092.23 KFM06629.1 - 1.3e-94 314.9 0.1 1.5e-38 132.3 0.0 3.1 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_2 PF13519.1 KFM06629.1 - 1.5e-31 109.8 0.1 5.9e-11 42.7 0.2 3.2 3 0 0 3 3 3 3 von Willebrand factor type A domain EGF PF00008.22 KFM06629.1 - 1.5e-14 53.5 23.7 3.8e-08 33.1 5.8 2.6 2 0 0 2 2 2 2 EGF-like domain Med25_VWA PF11265.3 KFM06629.1 - 0.026 13.5 0.0 3.4 6.6 0.0 2.7 2 0 0 2 2 2 0 Mediator complex subunit 25 von Willebrand factor type A AsnC_trans_reg PF01037.16 KFM06629.1 - 0.14 11.8 0.0 0.4 10.4 0.0 1.7 1 0 0 1 1 1 0 AsnC family EGF_2 PF07974.8 KFM06629.1 - 3.4 7.9 28.9 6.3 7.0 8.1 2.7 2 0 0 2 2 2 0 EGF-like domain PH PF00169.24 KFM06630.1 - 7.3e-22 77.5 1.9 1.6e-10 41.1 0.0 2.8 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 KFM06630.1 - 5.9e-06 26.5 5.8 0.031 14.5 0.1 3.9 2 2 0 2 2 2 2 Pleckstrin homology domain IncA PF04156.9 KFM06630.1 - 0.00032 20.3 3.0 0.00086 18.9 2.1 1.7 1 0 0 1 1 1 1 IncA protein APG6 PF04111.7 KFM06630.1 - 0.0084 15.1 8.9 0.02 13.9 6.2 1.6 1 0 0 1 1 1 1 Autophagy protein Apg6 V_ATPase_I PF01496.14 KFM06630.1 - 0.033 12.0 1.9 0.055 11.3 1.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LIM PF00412.17 KFM06631.1 - 8.8e-44 147.4 43.0 1.2e-14 54.1 1.3 5.0 4 1 1 5 5 5 4 LIM domain VHP PF02209.14 KFM06631.1 - 2e-17 62.6 0.7 3.1e-17 61.9 0.5 1.3 1 0 0 1 1 1 1 Villin headpiece domain Med27 PF11571.3 KFM06631.1 - 8.7 6.5 16.7 8.6 6.5 1.3 5.0 3 2 1 4 4 4 0 Mediator complex subunit 27 RAI16-like PF10257.4 KFM06632.1 - 2.1e-133 444.6 3.8 2.6e-133 444.3 2.6 1.1 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein TruB_N PF01509.13 KFM06633.1 - 8e-49 165.6 0.0 1.2e-48 165.0 0.0 1.3 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PseudoU_synth_2 PF00849.17 KFM06633.1 - 0.065 13.0 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 RNA pseudouridylate synthase GDNF PF02351.11 KFM06636.1 - 1.8e-41 140.4 48.4 4.4e-19 68.7 4.8 3.1 3 0 0 3 3 3 3 GDNF/GAS1 domain CENP-F_leu_zip PF10473.4 KFM06637.1 - 0.0091 15.8 17.6 0.0091 15.8 12.2 2.7 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Syntaxin-6_N PF09177.6 KFM06637.1 - 0.023 15.0 5.1 0.023 15.0 3.5 2.5 2 1 1 3 3 3 0 Syntaxin 6, N-terminal ABC_transp_aux PF09822.4 KFM06637.1 - 0.16 11.4 5.5 0.19 11.1 3.8 1.1 1 0 0 1 1 1 0 ABC-type uncharacterized transport system PilJ PF13675.1 KFM06637.1 - 0.21 11.8 3.4 0.16 12.2 1.0 1.8 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term PRP1_N PF06424.7 KFM06637.1 - 1.5 9.1 16.4 52 4.1 11.4 2.7 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal Fib_alpha PF08702.5 KFM06637.1 - 2.8 8.0 15.6 0.035 14.2 2.1 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Viral_P18 PF04521.8 KFM06637.1 - 9.5 5.6 16.2 5 6.6 1.8 2.5 2 1 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Lipase PF00151.14 KFM06638.1 - 2.5e-57 194.5 0.0 2.8e-57 194.4 0.0 1.0 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.2 KFM06638.1 - 3.4e-06 27.1 0.1 4.1e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFM06638.1 - 0.0019 17.9 0.0 0.002 17.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase PF00151.14 KFM06639.1 - 4.4e-67 226.6 0.0 5.3e-67 226.3 0.0 1.0 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.2 KFM06639.1 - 4.3e-05 23.5 0.0 5.1e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFM06639.1 - 0.022 14.5 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2305 PF10230.4 KFM06639.1 - 0.091 12.1 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Lipase PF00151.14 KFM06640.1 - 1.1e-61 208.9 0.1 1.3e-61 208.6 0.1 1.1 1 0 0 1 1 1 1 Lipase PLAT PF01477.18 KFM06640.1 - 1e-08 35.5 0.3 1.8e-08 34.7 0.2 1.4 1 0 0 1 1 1 1 PLAT/LH2 domain HSP70 PF00012.15 KFM06641.1 - 9.6e-06 23.7 0.0 0.051 11.4 0.0 3.1 3 0 0 3 3 3 3 Hsp70 protein Exonuc_X-T_C PF08411.5 KFM06641.1 - 0.071 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Exonuclease C-terminal FGGY_C PF02782.11 KFM06641.1 - 0.18 11.3 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Enolase_C PF00113.17 KFM06642.1 - 9.7e-25 87.1 0.0 3e-24 85.5 0.0 1.8 1 1 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 KFM06642.1 - 7.4e-14 51.8 0.6 7e-09 35.7 0.1 2.3 2 0 0 2 2 2 2 Enolase, N-terminal domain Sortase PF04203.8 KFM06642.1 - 0.14 11.7 0.1 0.28 10.7 0.1 1.5 1 0 0 1 1 1 0 Sortase family DUF3452 PF11934.3 KFM06643.1 - 0.3 10.4 13.7 0.081 12.2 6.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3452) Homeobox PF00046.24 KFM06644.1 - 0.044 13.3 0.4 0.061 12.9 0.3 1.2 1 0 0 1 1 1 0 Homeobox domain Ion_trans_2 PF07885.11 KFM06645.1 - 4.7e-31 106.3 21.3 5.6e-19 67.6 2.7 3.1 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.26 KFM06645.1 - 0.0005 19.3 21.9 0.00061 19.0 3.9 2.7 2 1 0 2 2 2 2 Ion transport protein MFS_1 PF07690.11 KFM06646.1 - 1.7e-45 155.2 36.6 1.1e-38 132.8 18.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFM06646.1 - 8.6e-14 50.9 18.4 8.9e-10 37.7 0.3 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter LacY_symp PF01306.14 KFM06646.1 - 0.0031 16.1 16.5 0.0071 14.9 5.0 2.9 2 1 0 2 2 2 2 LacY proton/sugar symporter PDZ_2 PF13180.1 KFM06647.1 - 1.3e-08 34.6 0.1 3.2e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain C1_1 PF00130.17 KFM06647.1 - 1e-07 31.5 15.0 1.9e-07 30.6 10.4 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PDZ PF00595.19 KFM06647.1 - 3.4e-07 30.3 0.1 9.9e-07 28.8 0.1 1.8 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) DUF2404 PF10296.4 KFM06647.1 - 0.00026 21.0 0.0 0.00062 19.8 0.0 1.7 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) GRASP55_65 PF04495.9 KFM06647.1 - 0.001 19.0 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain IncA PF04156.9 KFM06647.1 - 0.024 14.2 4.5 0.049 13.2 3.1 1.5 1 0 0 1 1 1 0 IncA protein Glyco_hydro_67N PF03648.9 KFM06647.1 - 0.13 12.2 0.3 0.41 10.6 0.0 2.0 2 0 0 2 2 2 0 Glycosyl hydrolase family 67 N-terminus Homeobox PF00046.24 KFM06648.1 - 6.1e-22 77.0 2.5 1.2e-21 76.0 1.7 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFM06648.1 - 0.084 12.5 0.0 0.39 10.4 0.0 2.0 2 0 0 2 2 2 0 Homeobox KN domain RBD-FIP PF09457.5 KFM06649.1 - 1.8e-21 75.6 4.7 1.8e-21 75.6 3.3 1.9 2 0 0 2 2 2 1 FIP domain C2 PF00168.25 KFM06649.1 - 2e-17 62.7 0.0 4.8e-17 61.5 0.0 1.7 1 0 0 1 1 1 1 C2 domain DUF2693 PF10902.3 KFM06649.1 - 0.1 12.4 0.9 4.6 7.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2693) DivIC PF04977.10 KFM06649.1 - 3 7.3 5.2 3.1 7.3 0.5 2.3 2 0 0 2 2 2 0 Septum formation initiator Peptidase_A21 PF03566.8 KFM06650.1 - 0.015 13.4 3.4 0.023 12.8 2.4 1.2 1 0 0 1 1 1 0 Peptidase family A21 c-SKI_SMAD_bind PF08782.5 KFM06650.1 - 0.067 13.3 1.0 0.59 10.2 0.1 2.4 2 1 0 2 2 2 0 c-SKI Smad4 binding domain Bap31 PF05529.7 KFM06650.1 - 2.3 7.6 12.5 0.17 11.3 4.7 1.8 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Cullin PF00888.17 KFM06651.1 - 5.2e-14 51.7 0.1 5.7e-14 51.5 0.1 1.1 1 0 0 1 1 1 1 Cullin family Exo70 PF03081.10 KFM06651.1 - 0.03 13.1 0.1 0.03 13.1 0.1 1.3 2 0 0 2 2 2 0 Exo70 exocyst complex subunit PCI PF01399.22 KFM06653.1 - 4.1e-15 55.9 0.0 4.1e-15 55.9 0.0 4.2 5 0 0 5 5 5 1 PCI domain Avl9 PF09794.4 KFM06654.1 - 7.3e-11 41.1 0.1 4.7e-07 28.6 0.0 2.1 1 1 1 2 2 2 2 Transport protein Avl9 SPA PF08616.5 KFM06654.1 - 9.5e-11 41.3 0.0 2.1e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis DUF2347 PF09804.4 KFM06654.1 - 1.5e-08 34.2 0.1 2.4e-08 33.5 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Mtc PF03820.12 KFM06655.1 - 1.1e-32 112.9 0.0 1.3e-32 112.7 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier AhpC-TSA PF00578.16 KFM06656.1 - 4.7e-36 123.1 0.0 6e-36 122.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KFM06656.1 - 1e-16 60.8 0.0 1.2e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 KFM06656.1 - 1.4e-07 30.9 0.1 2.3e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Pkinase PF00069.20 KFM06657.1 - 2.1e-62 210.6 0.0 3.2e-62 210.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM06657.1 - 8.1e-34 116.8 0.0 1.2e-33 116.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.14 KFM06657.1 - 2.1e-23 82.6 0.1 6.1e-23 81.1 0.0 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain Kinase-like PF14531.1 KFM06657.1 - 0.00049 19.1 0.0 0.00076 18.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RRM_1 PF00076.17 KFM06659.1 - 1.8e-59 197.2 0.1 2.1e-21 75.2 0.0 4.2 3 1 1 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM06659.1 - 6.1e-32 109.4 0.2 2.3e-14 53.1 0.0 4.0 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM06659.1 - 4.1e-31 106.6 0.4 1.2e-10 41.0 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFM06659.1 - 7.7e-05 22.3 0.5 0.037 13.7 0.0 3.3 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif Calcipressin PF04847.7 KFM06659.1 - 8.4e-05 22.2 0.0 0.056 13.0 0.0 2.5 2 0 0 2 2 2 2 Calcipressin Nup35_RRM PF05172.8 KFM06659.1 - 0.00077 19.1 0.2 0.3 10.8 0.2 3.5 1 1 1 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KFM06659.1 - 0.0061 16.3 0.0 4.5 7.1 0.0 3.0 3 0 0 3 3 3 1 RNA binding motif RNA_bind PF08675.6 KFM06659.1 - 0.078 12.9 0.1 4.4 7.3 0.0 2.7 2 0 0 2 2 2 0 RNA binding domain HATPase_c PF02518.21 KFM06659.1 - 0.087 12.5 0.0 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BAG PF02179.11 KFM06660.1 - 3.6e-20 71.8 4.2 5.9e-20 71.1 2.9 1.3 1 0 0 1 1 1 1 BAG domain Syja_N PF02383.13 KFM06661.1 - 1.8e-93 312.8 1.1 3.1e-93 312.0 0.7 1.4 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 KFM06661.1 - 4.3e-32 109.8 0.0 1.7e-31 107.9 0.0 2.1 2 0 0 2 2 2 1 Inositol phosphatase MCM_bind PF09739.4 KFM06662.1 - 7.1e-41 138.6 0.2 1.2e-40 137.8 0.1 1.4 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor Racemase_4 PF13615.1 KFM06662.1 - 4.6e-36 123.1 0.5 1.5e-35 121.5 0.1 2.1 2 0 0 2 2 2 1 Putative alanine racemase DDHD PF02862.12 KFM06663.1 - 5.1e-52 176.9 0.2 3e-50 171.1 0.0 2.2 2 0 0 2 2 2 1 DDHD domain SAM_1 PF00536.25 KFM06663.1 - 6.3e-13 48.6 0.0 1.4e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) WWE PF02825.15 KFM06663.1 - 5.1e-07 29.0 1.3 0.0047 16.3 0.1 2.6 1 1 1 2 2 2 2 WWE domain SAM_2 PF07647.12 KFM06663.1 - 5.9e-05 22.8 0.0 0.00018 21.2 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.5 KFM06663.1 - 0.0044 16.8 0.0 0.018 14.9 0.0 2.0 2 0 0 2 2 2 1 IGR protein motif PAP2 PF01569.16 KFM06664.1 - 4.7e-24 84.5 0.9 7.9e-24 83.7 0.6 1.3 1 0 0 1 1 1 1 PAP2 superfamily ATE_C PF04377.10 KFM06665.1 - 2.5e-45 153.6 0.4 1.4e-44 151.2 0.2 2.2 2 1 1 3 3 3 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 KFM06665.1 - 6.1e-10 38.7 2.2 1.6e-09 37.4 1.5 1.8 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus CPW_WPC PF09717.5 KFM06665.1 - 1.3 9.6 0.0 1.3 9.6 0.0 3.2 3 0 0 3 3 3 0 Plasmodium falciparum domain of unknown function (CPW_WPC) Nse4_C PF08743.5 KFM06666.1 - 9.5e-26 89.6 0.2 2.1e-25 88.5 0.0 1.7 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 KFM06666.1 - 5.4e-17 61.3 0.3 1.4e-16 60.0 0.2 1.7 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Plant_tran PF04827.9 KFM06666.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Plant transposon protein PH PF00169.24 KFM06668.1 - 1.6e-31 108.5 0.1 8.7e-19 67.6 0.0 2.4 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 KFM06668.1 - 6.2e-13 48.9 1.2 5.4e-07 29.8 0.3 4.0 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 KFM06668.1 - 2.1e-12 46.9 0.1 1.6e-05 24.8 0.0 3.0 2 1 0 2 2 2 2 Pleckstrin homology domain Mcp5_PH PF12814.2 KFM06668.1 - 1.1e-07 31.7 0.0 0.0089 15.9 0.0 2.4 2 0 0 2 2 2 2 Meiotic cell cortex C-terminal pleckstrin homology PH_9 PF15410.1 KFM06668.1 - 1.7e-07 31.4 0.3 0.025 14.7 0.1 2.6 2 1 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.1 KFM06668.1 - 8.9e-05 22.3 0.9 0.015 15.1 0.1 2.8 2 2 0 2 2 2 1 PH domain Trypsin_2 PF13365.1 KFM06669.1 - 1.5e-22 79.8 0.3 2.3e-22 79.2 0.2 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 KFM06669.1 - 7.1e-17 61.7 0.0 1e-16 61.2 0.0 1.2 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.1 KFM06669.1 - 2.4e-10 40.1 0.5 2.4e-10 40.1 0.4 2.1 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.19 KFM06669.1 - 4.3e-10 39.6 0.2 1.3e-09 38.1 0.1 1.9 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Peptidase_S46 PF10459.4 KFM06669.1 - 1e-06 27.5 0.8 0.015 13.7 0.0 2.2 2 0 0 2 2 2 2 Peptidase S46 Peptidase_S32 PF05579.8 KFM06669.1 - 1.7e-05 23.9 0.1 0.073 12.0 0.0 2.1 2 0 0 2 2 2 2 Equine arteritis virus serine endopeptidase S32 LSM PF01423.17 KFM06669.1 - 0.0048 16.4 0.0 0.014 14.9 0.0 1.8 1 0 0 1 1 1 1 LSM domain GRASP55_65 PF04495.9 KFM06669.1 - 0.011 15.7 0.0 0.029 14.3 0.0 1.7 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain HAS-barrel PF09378.5 KFM06669.1 - 0.049 13.5 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 HAS barrel domain SRCR PF00530.13 KFM06670.1 - 1.6e-133 435.7 52.4 3.6e-33 113.8 4.9 4.1 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 KFM06670.1 - 3.1e-13 49.7 10.1 0.065 13.4 0.1 4.4 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain DUF4508 PF14969.1 KFM06670.1 - 0.052 13.5 0.0 2.3e+02 1.8 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4508) SRCR PF00530.13 KFM06671.1 - 5.7e-35 119.6 7.0 6.3e-35 119.4 4.9 1.0 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 KFM06671.1 - 0.0045 17.2 0.7 0.0056 16.8 0.2 1.4 1 1 0 1 1 1 1 Scavenger receptor cysteine-rich domain Zona_pellucida PF00100.18 KFM06672.1 - 2.7e-09 36.8 0.0 2.9e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Zona_pellucida PF00100.18 KFM06673.1 - 2.9e-24 85.9 2.8 3.1e-24 85.8 2.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain SRCR PF00530.13 KFM06674.1 - 1.5e-47 159.9 16.0 2e-32 111.4 3.8 2.0 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 KFM06674.1 - 1.4e-06 28.4 4.3 0.011 15.9 0.2 2.4 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain SapB_2 PF03489.12 KFM06674.1 - 0.29 11.2 1.5 71 3.5 0.1 3.2 3 0 0 3 3 3 0 Saposin-like type B, region 2 DUF3027 PF11228.3 KFM06674.1 - 1.8 8.1 5.5 9.7 5.8 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3027) Zona_pellucida PF00100.18 KFM06675.1 - 5.7e-10 39.0 0.1 6e-10 39.0 0.1 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Zona_pellucida PF00100.18 KFM06676.1 - 3e-24 85.8 2.5 3.3e-24 85.7 1.7 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain SRCR PF00530.13 KFM06677.1 - 2.6e-65 216.9 19.2 1.7e-32 111.6 3.3 2.0 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 KFM06677.1 - 2.9e-07 30.6 8.5 0.00022 21.4 0.7 2.8 2 1 0 2 2 2 2 Scavenger receptor cysteine-rich domain SapB_2 PF03489.12 KFM06677.1 - 1.2 9.2 5.2 73 3.5 0.1 4.3 5 0 0 5 5 5 0 Saposin-like type B, region 2 Zona_pellucida PF00100.18 KFM06678.1 - 2.6e-23 82.8 1.1 2.8e-23 82.7 0.8 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain dNK PF01712.14 KFM06678.1 - 0.14 12.0 0.4 0.41 10.5 0.1 1.7 1 1 1 2 2 2 0 Deoxynucleoside kinase Zona_pellucida PF00100.18 KFM06679.1 - 0.012 15.0 0.1 0.012 15.0 0.1 1.0 1 0 0 1 1 1 0 Zona pellucida-like domain TehB PF03848.9 KFM06679.1 - 0.11 11.6 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TehB DUF4506 PF14958.1 KFM06680.1 - 1.4e-16 60.3 0.1 2.7e-16 59.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4506) Rnk_N PF14760.1 KFM06680.1 - 0.15 12.1 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 Rnk N-terminus ABC_tran PF00005.22 KFM06680.1 - 4.8 7.4 5.9 19 5.5 0.0 2.9 2 2 0 3 3 3 0 ABC transporter Reprolysin PF01421.14 KFM06681.1 - 4.4e-55 186.3 0.0 4.4e-55 186.3 0.0 2.1 3 0 0 3 3 2 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.14 KFM06681.1 - 6.8e-30 103.5 0.1 1.2e-29 102.7 0.1 1.3 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_CR PF08516.7 KFM06681.1 - 1.1e-29 102.8 5.0 1.1e-29 102.8 3.5 4.0 3 2 1 4 4 1 1 ADAM cysteine-rich Disintegrin PF00200.18 KFM06681.1 - 1.2e-24 86.3 27.4 1.2e-24 86.3 19.0 3.5 3 1 0 3 3 2 1 Disintegrin Reprolysin_5 PF13688.1 KFM06681.1 - 4.9e-21 75.5 0.3 4.9e-21 75.5 0.2 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KFM06681.1 - 5.6e-21 75.3 1.1 5.6e-21 75.3 0.7 1.7 2 0 0 2 2 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFM06681.1 - 1.9e-16 60.5 1.1 4.9e-16 59.2 0.7 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFM06681.1 - 3.6e-12 46.2 0.3 7.8e-12 45.1 0.2 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KFM06681.1 - 0.00013 21.7 0.1 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 Matrixin EB PF01683.13 KFM06681.1 - 0.0015 18.5 16.1 0.0015 18.5 11.2 4.6 3 1 1 4 4 1 1 EB module EGF_2 PF07974.8 KFM06681.1 - 0.0087 16.1 12.9 0.0087 16.1 9.0 5.9 3 1 1 4 4 2 1 EGF-like domain Peptidase_M57 PF12388.3 KFM06681.1 - 0.03 13.6 0.4 0.054 12.8 0.3 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase KTI12 PF08433.5 KFM06682.1 - 4.4e-18 65.4 2.1 5.7e-18 65.0 1.4 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 KFM06682.1 - 3.2e-05 23.8 0.1 0.00013 21.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain zf-H2C2_2 PF13465.1 KFM06683.1 - 4.1e-13 48.9 42.9 6.3e-07 29.3 2.6 6.2 6 0 0 6 6 6 4 Zinc-finger double domain zf-H2C2_5 PF13909.1 KFM06683.1 - 2.4e-07 30.5 44.7 0.0024 17.9 4.2 5.3 5 0 0 5 5 5 4 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 KFM06683.1 - 2e-05 24.6 49.5 0.12 12.7 5.8 5.4 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM06683.1 - 4.1 7.9 50.2 0.21 11.9 3.4 5.3 5 0 0 5 5 5 0 C2H2-type zinc finger Acyl-CoA_dh_1 PF00441.19 KFM06684.1 - 9.6e-51 171.8 0.6 2.7e-49 167.1 0.2 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KFM06684.1 - 4.5e-27 94.8 0.1 1.1e-26 93.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KFM06684.1 - 4.6e-25 88.4 0.0 8.2e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KFM06684.1 - 1.2e-18 66.3 0.0 2.1e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Homeobox PF00046.24 KFM06685.1 - 1.8e-19 69.0 1.5 2.8e-19 68.4 1.0 1.3 1 0 0 1 1 1 1 Homeobox domain AHS1 PF02682.11 KFM06685.1 - 0.061 12.7 0.0 0.074 12.5 0.0 1.1 1 0 0 1 1 1 0 Allophanate hydrolase subunit 1 Homez PF11569.3 KFM06685.1 - 0.15 11.1 0.3 0.28 10.2 0.2 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Homeobox PF00046.24 KFM06686.1 - 3.5e-19 68.1 2.5 4.9e-19 67.7 1.7 1.2 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 KFM06686.1 - 0.026 13.5 0.5 0.035 13.1 0.3 1.3 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.6 KFM06686.1 - 0.036 13.7 0.1 0.06 13.0 0.1 1.4 1 0 0 1 1 1 0 Homeobox KN domain WD40 PF00400.27 KFM06687.1 - 1.6e-28 97.5 7.4 2.7e-08 33.3 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat 7tm_1 PF00001.16 KFM06689.1 - 7.8e-42 143.1 16.4 1.1e-41 142.6 11.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 KFM06689.1 - 6.7e-06 25.4 14.4 6.7e-06 25.4 10.0 1.9 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Git3 PF11710.3 KFM06689.1 - 4.9e-05 22.9 11.8 4.9e-05 22.9 8.2 1.6 1 1 1 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7TM_GPCR_Srbc PF10316.4 KFM06689.1 - 0.00014 21.2 8.3 0.00014 21.2 5.7 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srbc DUF2243 PF10002.4 KFM06689.1 - 0.0099 15.6 0.3 0.028 14.2 0.2 1.8 1 0 0 1 1 1 1 Predicted membrane protein (DUF2243) DUF2516 PF10724.4 KFM06689.1 - 5.2 7.1 12.9 2.5 8.1 3.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2516) Sulfotransfer_1 PF00685.22 KFM06691.1 - 8.1e-16 58.0 0.0 1.5e-14 53.9 0.0 2.2 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 KFM06691.1 - 5e-09 37.2 0.2 9e-09 36.4 0.1 1.5 1 0 0 1 1 1 1 Sulfotransferase family PVL_ORF50 PF07768.6 KFM06691.1 - 0.13 12.2 0.1 0.13 12.2 0.1 1.8 2 0 0 2 2 2 0 PVL ORF-50-like family Aminotran_3 PF00202.16 KFM06692.1 - 7.9e-116 386.5 0.0 9.9e-116 386.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 KFM06692.1 - 0.016 14.1 0.0 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Hydrolase_like PF13242.1 KFM06693.1 - 1e-20 73.1 0.0 4.5e-19 67.9 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 KFM06693.1 - 2.7e-09 36.8 0.0 4.5e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KFM06693.1 - 2.6e-08 34.2 0.1 2.7e-07 30.9 0.0 2.3 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFM06693.1 - 1e-05 26.0 0.2 5.7e-05 23.6 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase UBA PF00627.26 KFM06693.1 - 0.36 10.7 1.6 15 5.5 0.0 3.1 3 0 0 3 3 3 0 UBA/TS-N domain FAM53 PF15242.1 KFM06694.1 - 6.4e-106 354.4 29.5 2e-105 352.8 20.4 1.8 1 1 0 1 1 1 1 Family of FAM53 Methyltransf_31 PF13847.1 KFM06695.1 - 1.1e-19 70.5 0.0 1.4e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFM06695.1 - 9.9e-15 55.0 0.0 1.4e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFM06695.1 - 2.1e-10 40.5 0.0 5.8e-10 39.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFM06695.1 - 1.7e-09 37.6 0.0 2.6e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFM06695.1 - 9.8e-09 35.6 0.0 1.4e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFM06695.1 - 2.1e-08 34.5 0.0 3.5e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFM06695.1 - 1.3e-07 31.1 0.0 2.3e-07 30.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 KFM06695.1 - 1.4e-07 30.9 0.0 1.6e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 KFM06695.1 - 4.4e-06 26.9 0.0 7.4e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 KFM06695.1 - 4.4e-05 23.0 0.0 6.8e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_4 PF02390.12 KFM06695.1 - 0.00017 20.6 0.0 0.0004 19.4 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.15 KFM06695.1 - 0.00053 19.1 0.0 0.00074 18.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 KFM06695.1 - 0.0017 17.5 0.0 0.0021 17.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.7 KFM06695.1 - 0.0023 17.3 0.0 0.003 16.9 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW TehB PF03848.9 KFM06695.1 - 0.0087 15.2 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.14 KFM06695.1 - 0.012 15.1 0.0 0.017 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 KFM06695.1 - 0.035 13.7 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain AdoMet_MTase PF07757.8 KFM06695.1 - 0.051 13.7 0.0 0.084 12.9 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Methyltransf_24 PF13578.1 KFM06695.1 - 0.083 13.7 0.0 0.12 13.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Pox_MCEL PF03291.11 KFM06695.1 - 0.12 11.1 0.0 0.48 9.2 0.0 1.8 2 0 0 2 2 2 0 mRNA capping enzyme GidB PF02527.10 KFM06695.1 - 0.15 11.1 0.1 1.2 8.2 0.1 2.0 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G Cluap1 PF10234.4 KFM06696.1 - 0.0046 16.2 2.3 0.0066 15.6 1.6 1.2 1 0 0 1 1 1 1 Clusterin-associated protein-1 Rabaptin PF03528.10 KFM06696.1 - 0.017 15.0 2.4 0.017 15.0 1.6 1.9 2 0 0 2 2 2 0 Rabaptin KorB PF08535.5 KFM06696.1 - 0.037 14.1 0.5 0.072 13.2 0.4 1.4 1 0 0 1 1 1 0 KorB domain Spc7 PF08317.6 KFM06696.1 - 0.042 12.5 3.4 0.07 11.7 2.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein BBP1_C PF15272.1 KFM06696.1 - 0.8 9.2 7.7 0.038 13.5 0.9 2.0 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal FlxA PF14282.1 KFM06696.1 - 1.3 9.0 11.4 0.042 13.8 2.9 2.2 2 0 0 2 2 2 0 FlxA-like protein OTU PF02338.14 KFM06698.1 - 2.2e-32 112.2 0.1 5.1e-32 111.0 0.1 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease zf-RanBP PF00641.13 KFM06698.1 - 8.2e-11 40.8 30.5 6.1e-06 25.2 4.3 3.7 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others DZR PF12773.2 KFM06698.1 - 0.3 10.9 17.2 3.3 7.6 4.8 2.7 1 1 1 2 2 2 0 Double zinc ribbon 2-Hacid_dh_C PF02826.14 KFM06699.1 - 2.7e-55 186.2 0.0 4.7e-55 185.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFM06699.1 - 3.7e-29 100.8 0.1 4.6e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KFM06699.1 - 0.03 14.1 0.0 0.067 13.0 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Linocin_M18 PF04454.7 KFM06700.1 - 0.055 12.3 0.3 1.4 7.8 0.0 2.3 2 0 0 2 2 2 0 Encapsulating protein for peroxidase TPR_2 PF07719.12 KFM06700.1 - 0.3 11.1 10.5 0.59 10.1 0.5 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 KFM06700.1 - 0.45 10.1 8.2 5.9 6.6 0.6 4.3 5 0 0 5 5 5 0 TPR repeat HEM4 PF02602.10 KFM06701.1 - 2.3e-48 164.4 0.0 2.6e-48 164.2 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD BCIP PF13862.1 KFM06702.1 - 6.8e-64 214.9 4.2 8.1e-64 214.7 2.9 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein DPRP PF04244.8 KFM06702.1 - 0.05 13.1 0.1 0.6 9.5 0.0 2.2 1 1 1 2 2 2 0 Deoxyribodipyrimidine photo-lyase-related protein HA2 PF04408.18 KFM06703.1 - 1.1e-21 76.7 0.3 3.4e-21 75.1 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KFM06703.1 - 2.1e-15 56.5 0.0 5.3e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 KFM06703.1 - 0.028 14.5 0.0 0.13 12.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain Reprolysin PF01421.14 KFM06704.1 - 2.5e-71 239.3 0.0 2.5e-71 239.3 0.0 1.8 2 0 0 2 2 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.7 KFM06704.1 - 3.6e-34 117.3 4.3 3.6e-34 117.3 3.0 3.2 3 1 0 3 3 2 1 ADAM cysteine-rich Pep_M12B_propep PF01562.14 KFM06704.1 - 6.8e-32 110.0 0.3 1.2e-31 109.2 0.2 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide Disintegrin PF00200.18 KFM06704.1 - 1.1e-24 86.4 26.0 1.1e-24 86.4 18.0 3.9 3 1 1 4 4 3 1 Disintegrin Reprolysin_5 PF13688.1 KFM06704.1 - 2.6e-21 76.4 0.0 6.5e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 KFM06704.1 - 1.4e-15 57.7 0.0 2.6e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KFM06704.1 - 2.1e-15 57.3 0.0 4.5e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFM06704.1 - 2.5e-15 56.5 0.0 4.3e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.8 KFM06704.1 - 0.0064 16.1 0.1 0.017 14.6 0.1 1.7 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Peptidase_M66 PF10462.4 KFM06704.1 - 0.078 11.8 0.3 0.13 11.1 0.2 1.3 1 0 0 1 1 1 0 Peptidase M66 DUF1025 PF06262.6 KFM06704.1 - 0.2 11.4 0.2 0.39 10.5 0.1 1.4 1 0 0 1 1 1 0 Possibl zinc metallo-peptidase Peptidase_M10 PF00413.19 KFM06704.1 - 0.22 11.2 0.2 0.37 10.4 0.2 1.4 1 1 0 1 1 1 0 Matrixin ALMS_motif PF15309.1 KFM06706.1 - 5.5e-11 42.4 0.6 1.5e-10 41.0 0.4 1.8 1 0 0 1 1 1 1 ALMS motif IBB PF01749.15 KFM06706.1 - 0.014 15.5 0.1 0.043 13.9 0.1 1.8 1 0 0 1 1 1 0 Importin beta binding domain GlnD_UR_UTase PF08335.6 KFM06706.1 - 0.064 13.0 0.6 0.13 12.1 0.4 1.4 1 0 0 1 1 1 0 GlnD PII-uridylyltransferase DOCK-C2 PF14429.1 KFM06707.1 - 4.4e-32 111.2 0.0 6.1e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Herpes_BBRF1 PF04793.7 KFM06708.1 - 0.038 12.7 0.3 0.039 12.7 0.2 1.1 1 0 0 1 1 1 0 BRRF1-like protein RTTN_N PF14726.1 KFM06708.1 - 0.059 13.9 0.1 0.059 13.9 0.1 1.1 1 0 0 1 1 1 0 Rotatin, an armadillo repeat protein, centriole functioning Glu_syn_central PF04898.9 KFM06708.1 - 0.11 11.7 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Glutamate synthase central domain Rota_NS6 PF04866.7 KFM06708.1 - 0.13 12.2 0.4 3.3 7.7 0.1 2.0 1 1 1 2 2 2 0 Rotavirus non-structural protein 6 Flu_C_NS2 PF03555.9 KFM06708.1 - 0.14 12.0 0.3 0.21 11.5 0.2 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS2) FAM196 PF15265.1 KFM06709.1 - 1.6e-186 621.5 20.6 1.8e-186 621.3 14.3 1.0 1 0 0 1 1 1 1 FAM196 family ATP-synt_ab_N PF02874.18 KFM06709.1 - 0.066 13.4 0.0 3.9 7.7 0.1 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, beta-barrel domain Ded_cyto PF06920.8 KFM06711.1 - 1.3e-40 138.5 0.1 1.3e-40 138.5 0.1 1.7 2 0 0 2 2 2 1 Dedicator of cytokinesis Neuropeptide_S PF14993.1 KFM06712.1 - 1.8e-35 120.4 0.1 2.3e-35 120.0 0.1 1.2 1 0 0 1 1 1 1 Neuropeptide S precursor protein Claudin_2 PF13903.1 KFM06713.1 - 1.9e-11 43.9 14.0 2.7e-11 43.4 9.7 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF2393 PF09624.5 KFM06713.1 - 0.24 10.9 7.3 0.98 8.9 0.1 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF2393) Ni_hydr_CYTB PF01292.15 KFM06713.1 - 0.77 9.1 5.2 0.28 10.5 1.4 1.9 2 1 0 2 2 2 0 Prokaryotic cytochrome b561 Y_phosphatase PF00102.22 KFM06714.1 - 3.1e-147 488.1 9.4 1.7e-85 286.1 0.8 2.4 2 1 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.15 KFM06714.1 - 0.00044 19.8 0.1 0.0021 17.6 0.0 2.2 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFM06714.1 - 0.00078 19.7 0.1 0.007 16.6 0.0 2.5 3 0 0 3 3 3 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KFM06714.1 - 0.024 14.6 0.0 0.11 12.4 0.0 2.2 2 0 0 2 2 2 0 Inositol hexakisphosphate FHA PF00498.21 KFM06715.1 - 1.9e-13 50.3 0.0 2.8e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 FHA domain PP1_bind PF15276.1 KFM06716.1 - 2.1e-24 85.2 0.8 3.1e-24 84.7 0.5 1.3 1 0 0 1 1 1 1 Protein phosphatase 1 binding K167R PF08065.7 KFM06718.1 - 8.8e-17 61.2 4.6 1.7e-09 37.7 1.5 2.1 1 1 1 2 2 2 2 K167R (NUC007) repeat RR_TM4-6 PF06459.7 KFM06718.1 - 0.77 9.6 4.6 0.82 9.5 3.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Prim_Zn_Ribbon PF08273.7 KFM06719.1 - 0.00084 19.3 5.9 1.1e+02 2.9 0.0 5.8 6 0 0 6 6 6 0 Zinc-binding domain of primase-helicase Romo1 PF10247.4 KFM06719.1 - 0.74 10.0 27.7 9.4 6.5 0.5 5.1 1 1 4 5 5 5 0 Reactive mitochondrial oxygen species modulator 1 MAGP PF05507.6 KFM06721.1 - 0.048 13.4 0.7 0.26 11.1 0.0 2.1 2 0 0 2 2 2 0 Microfibril-associated glycoprotein (MAGP) DNA_binding_1 PF01035.15 KFM06722.1 - 6.5e-26 89.8 0.0 7.7e-26 89.6 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain HTH_15 PF12324.3 KFM06722.1 - 0.071 12.7 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase Methyltransf_1N PF02870.10 KFM06722.1 - 0.14 12.7 0.1 0.21 12.2 0.1 1.3 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain TIG PF01833.19 KFM06723.1 - 9.2e-13 47.9 0.1 9.2e-13 47.9 0.1 2.5 2 0 0 2 2 2 1 IPT/TIG domain Glutaredoxin PF00462.19 KFM06724.1 - 9e-40 134.4 0.1 1.1e-17 63.6 0.0 3.3 3 0 0 3 3 3 2 Glutaredoxin Thioredoxin PF00085.15 KFM06724.1 - 1e-18 66.9 0.2 4.8e-18 64.7 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 KFM06724.1 - 7.5e-08 32.5 0.1 6.7e-06 26.2 0.0 3.6 3 2 1 4 4 4 1 Thioredoxin-like domain SH3BGR PF04908.10 KFM06724.1 - 7.4e-06 25.8 0.0 0.066 13.1 0.0 2.6 2 0 0 2 2 2 2 SH3-binding, glutamic acid-rich protein DIM1 PF02966.11 KFM06724.1 - 9.6e-05 21.9 0.0 0.0002 20.8 0.0 1.5 1 0 0 1 1 1 1 Mitosis protein DIM1 ArsC PF03960.10 KFM06724.1 - 0.00016 21.7 0.0 0.99 9.5 0.0 3.3 3 0 0 3 3 3 1 ArsC family Thioredoxin_8 PF13905.1 KFM06724.1 - 0.00033 20.6 0.1 0.063 13.3 0.0 3.4 2 1 1 3 3 3 1 Thioredoxin-like Phosducin PF02114.11 KFM06724.1 - 0.00077 18.2 0.0 0.0015 17.2 0.0 1.5 1 0 0 1 1 1 1 Phosducin Thioredoxin_3 PF13192.1 KFM06724.1 - 0.0031 17.2 0.2 0.019 14.7 0.0 2.3 2 1 1 3 3 3 1 Thioredoxin domain TrbC_Ftype PF09673.5 KFM06724.1 - 0.016 14.7 0.0 0.051 13.1 0.0 1.8 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin assembly protein HyaE PF07449.6 KFM06724.1 - 0.018 14.8 0.1 0.16 11.8 0.0 2.6 3 1 1 4 4 4 0 Hydrogenase-1 expression protein HyaE FF PF01846.14 KFM06725.1 - 3.3e-22 78.1 11.3 3.7e-12 45.9 0.5 2.4 2 0 0 2 2 2 2 FF domain WW PF00397.21 KFM06725.1 - 3.6e-05 23.5 0.1 3.6e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 WW domain WD40 PF00400.27 KFM06726.1 - 8.1e-12 44.5 4.6 0.51 10.3 0.0 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat Y_phosphatase2 PF03162.8 KFM06726.1 - 0.0077 15.6 0.3 0.49 9.7 0.0 2.4 2 0 0 2 2 2 2 Tyrosine phosphatase family BNIP3 PF06553.7 KFM06727.1 - 9.9e-75 250.2 3.4 1.1e-74 250.1 2.4 1.0 1 0 0 1 1 1 1 BNIP3 Amidohydro_1 PF01979.15 KFM06729.1 - 9.3e-34 117.5 0.1 1.2e-33 117.1 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KFM06729.1 - 3.4e-10 40.4 0.0 6.2e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KFM06729.1 - 4.7e-10 39.1 2.5 7.6e-10 38.4 0.3 2.4 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 KFM06729.1 - 9.2e-05 21.8 0.6 0.0068 15.6 0.0 2.6 3 0 0 3 3 3 2 Amidohydrolase family Pkinase PF00069.20 KFM06730.1 - 3.1e-61 206.7 0.0 3.1e-61 206.7 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM06730.1 - 1.8e-35 122.2 0.1 2.8e-35 121.6 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM06730.1 - 1.6e-11 43.7 0.1 4e-11 42.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFM06730.1 - 0.0024 16.9 0.2 0.0049 15.9 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFM06730.1 - 0.0071 16.0 0.2 0.014 15.1 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Exo_endo_phos PF03372.18 KFM06731.1 - 1.3e-08 35.1 0.0 1.5e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UQ_con PF00179.21 KFM06731.1 - 0.07 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme PCNA_N PF00705.13 KFM06731.1 - 0.086 12.3 0.4 0.25 10.8 0.3 1.8 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, N-terminal domain RWD PF05773.17 KFM06731.1 - 0.11 12.3 0.0 0.24 11.3 0.0 1.5 1 1 0 1 1 1 0 RWD domain 7tm_1 PF00001.16 KFM06732.1 - 8.7e-51 172.5 15.2 1.1e-50 172.2 10.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM06732.1 - 2.7e-09 36.5 12.6 3.2e-09 36.3 8.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 KFM06732.1 - 4.8e-07 29.2 7.1 4.8e-07 29.2 4.9 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.4 KFM06732.1 - 1.5e-06 27.5 11.7 9.3e-06 24.9 7.7 2.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_4 PF13853.1 KFM06732.1 - 0.0053 16.5 4.5 0.0053 16.5 3.1 3.0 2 1 1 3 3 3 1 Olfactory receptor MgtE PF01769.11 KFM06732.1 - 2.1 8.6 11.1 1 9.6 0.3 2.8 3 0 0 3 3 3 0 Divalent cation transporter AA_kinase PF00696.23 KFM06734.1 - 4.2e-39 134.5 0.3 8.3e-39 133.5 0.2 1.5 1 0 0 1 1 1 1 Amino acid kinase family Aldedh PF00171.17 KFM06734.1 - 6.8e-15 54.3 0.0 7.1e-12 44.4 0.0 2.4 2 1 0 2 2 2 2 Aldehyde dehydrogenase family DTW PF03942.10 KFM06735.1 - 2.7e-45 154.0 0.2 3.5e-45 153.7 0.2 1.1 1 0 0 1 1 1 1 DTW domain Rav1p_C PF12234.3 KFM06736.1 - 9.2e-74 248.7 0.0 2.3e-71 240.7 0.0 3.1 2 1 0 2 2 2 1 RAVE protein 1 C terminal WD40 PF00400.27 KFM06736.1 - 2.5e-26 90.5 34.3 3.1e-06 26.8 0.0 12.7 13 0 0 13 13 13 8 WD domain, G-beta repeat Folate_carrier PF01770.13 KFM06736.1 - 0.53 8.7 0.6 1 7.7 0.4 1.4 1 0 0 1 1 1 0 Reduced folate carrier DUF758 PF05527.6 KFM06737.1 - 6.7e-93 309.4 8.4 7.5e-93 309.3 5.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF758) RAG1 PF12940.2 KFM06737.1 - 0.00051 18.5 0.8 0.00063 18.2 0.5 1.1 1 0 0 1 1 1 1 Recombination-activation protein 1 (RAG1) Pico_P2B PF01552.12 KFM06737.1 - 0.0043 17.1 1.0 0.013 15.6 0.3 2.1 1 1 0 1 1 1 1 Picornavirus 2B protein CH PF00307.26 KFM06737.1 - 0.0083 16.1 0.1 0.027 14.5 0.0 2.0 1 1 1 2 2 2 1 Calponin homology (CH) domain Nup54 PF13874.1 KFM06737.1 - 0.017 14.8 2.1 0.019 14.6 0.9 1.6 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 FadR_C PF07840.7 KFM06737.1 - 0.017 14.7 0.6 0.024 14.2 0.4 1.4 1 0 0 1 1 1 0 FadR C-terminal domain UCH PF00443.24 KFM06737.1 - 0.035 13.2 1.4 0.043 12.9 1.0 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF2408 PF10303.4 KFM06737.1 - 0.051 13.7 4.4 0.1 12.6 2.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) HD_3 PF13023.1 KFM06737.1 - 0.067 12.9 0.6 0.11 12.2 0.4 1.4 2 0 0 2 2 2 0 HD domain MaoC_dehydratas PF01575.14 KFM06738.1 - 1e-28 99.1 0.0 1.9e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain adh_short PF00106.20 KFM06738.1 - 2.1e-25 89.5 0.0 4.8e-25 88.4 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase SCP2 PF02036.12 KFM06738.1 - 2.1e-24 85.7 0.3 5e-24 84.5 0.2 1.7 1 0 0 1 1 1 1 SCP-2 sterol transfer family KR PF08659.5 KFM06738.1 - 9.6e-12 44.9 0.0 1.7e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 KR domain MaoC_dehydrat_N PF13452.1 KFM06738.1 - 1.6e-10 40.8 0.0 4.4e-10 39.4 0.0 1.7 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Alkyl_sulf_C PF14864.1 KFM06738.1 - 1.6e-06 28.0 0.1 3.3e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal DUF4589 PF15252.1 KFM06739.1 - 3.2e-70 236.3 0.1 3.6e-70 236.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4589) BTB PF00651.26 KFM06741.1 - 5.5e-25 87.5 0.0 7.7e-25 87.0 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.21 KFM06741.1 - 2.9e-23 80.7 30.6 8.8e-06 25.7 1.0 5.8 6 0 0 6 6 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM06741.1 - 2.6e-21 74.3 18.8 1.5e-05 25.0 0.2 5.7 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFM06741.1 - 9.1e-21 73.0 28.4 5.5e-08 32.7 0.1 6.4 7 0 0 7 7 6 4 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFM06741.1 - 7e-19 67.4 4.4 0.00037 20.5 0.2 5.8 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM06741.1 - 1.7e-12 47.0 13.8 0.01 16.0 0.3 6.2 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFM06741.1 - 8.2e-10 38.2 15.9 0.006 16.4 0.1 5.6 6 0 0 6 6 5 4 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KFM06741.1 - 6.3e-06 26.2 15.8 1.1 9.4 0.2 5.4 2 1 3 5 5 5 2 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 KFM06741.1 - 0.0021 18.1 12.3 0.11 12.6 0.5 3.5 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.5 KFM06741.1 - 0.014 15.3 13.5 0.86 9.6 1.5 4.7 4 1 0 4 4 4 0 Zinc ribbon domain SprT-like PF10263.4 KFM06741.1 - 0.029 14.0 8.1 1.6 8.3 2.2 2.9 1 1 1 2 2 2 0 SprT-like family Prok-RING_1 PF14446.1 KFM06741.1 - 0.042 13.5 6.8 19 5.1 0.0 4.8 5 0 0 5 5 5 0 Prokaryotic RING finger family 1 GAGA PF09237.6 KFM06741.1 - 0.078 12.5 1.2 1.7 8.2 0.1 2.6 2 0 0 2 2 2 0 GAGA factor zf-UBP PF02148.14 KFM06741.1 - 0.086 12.9 11.2 1.2 9.2 0.1 3.6 2 1 1 3 3 3 0 Zn-finger in ubiquitin-hydrolases and other protein LIM PF00412.17 KFM06741.1 - 0.16 12.0 0.3 0.16 12.0 0.2 3.7 3 1 2 5 5 5 0 LIM domain C1_4 PF07975.7 KFM06741.1 - 0.38 10.7 9.4 4.9 7.2 0.7 3.3 3 0 0 3 3 3 0 TFIIH C1-like domain zf-FCS PF06467.9 KFM06741.1 - 0.94 9.1 6.2 2.3 7.9 0.2 3.5 3 1 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif zf-H2C2_5 PF13909.1 KFM06741.1 - 1.2 9.5 21.2 0.5 10.7 0.8 5.0 5 1 0 5 5 4 0 C2H2-type zinc-finger domain zf-LYAR PF08790.6 KFM06741.1 - 1.2 8.8 0.0 1.2 8.8 0.0 3.8 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger zf-HYPF PF07503.7 KFM06741.1 - 1.3 8.4 9.5 4.9 6.6 1.0 3.6 3 1 0 3 3 3 0 HypF finger C1_1 PF00130.17 KFM06741.1 - 9.9 5.9 13.8 0.33 10.7 0.8 3.8 5 0 0 5 5 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) EST1_DNA_bind PF10373.4 KFM06742.1 - 1.6e-78 263.7 0.0 3.2e-78 262.7 0.0 1.5 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain PIN_4 PF13638.1 KFM06742.1 - 4e-23 81.9 0.0 4e-23 81.9 0.0 2.9 3 0 0 3 3 3 1 PIN domain EST1 PF10374.4 KFM06742.1 - 3.8e-22 78.6 0.2 1.1e-21 77.1 0.2 1.9 1 0 0 1 1 1 1 Telomerase activating protein Est1 TPR_11 PF13414.1 KFM06742.1 - 0.022 14.4 4.7 0.022 14.4 2.0 1.9 2 0 0 2 2 2 0 TPR repeat TPR_2 PF07719.12 KFM06742.1 - 0.34 10.9 1.7 4.4 7.4 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat PALP PF00291.20 KFM06744.1 - 6.8e-62 209.4 2.9 7.6e-62 209.2 2.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF3798 PF12683.2 KFM06744.1 - 0.022 13.8 0.0 0.035 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) DUF663 PF04950.7 KFM06745.1 - 3.7e-122 406.9 0.0 7e-122 406.0 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KFM06745.1 - 1.3e-20 72.6 0.0 2.8e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain DUF525 PF04379.9 KFM06746.1 - 2.7e-25 88.1 0.0 4.9e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF525) YccV-like PF08755.6 KFM06746.1 - 5.2e-05 23.1 1.2 0.00026 20.8 0.3 2.6 2 1 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like Vma12 PF11712.3 KFM06747.1 - 8.1e-31 106.6 0.1 9.8e-31 106.3 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Glycoprotein_B PF00606.13 KFM06747.1 - 0.065 11.2 0.1 0.075 11.0 0.1 1.0 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B Kinesin PF00225.18 KFM06748.1 - 5.5e-72 242.2 0.0 2e-41 141.8 0.0 2.0 2 0 0 2 2 2 2 Kinesin motor domain Prp19 PF08606.6 KFM06748.1 - 0.038 13.7 0.2 0.087 12.5 0.1 1.6 1 0 0 1 1 1 0 Prp19/Pso4-like Hemopexin PF00045.14 KFM06749.1 - 8e-26 89.5 9.0 6.2e-12 45.0 0.1 4.4 4 0 0 4 4 4 3 Hemopexin Somatomedin_B PF01033.12 KFM06749.1 - 1e-11 44.5 17.4 1.7e-11 43.8 12.1 1.4 1 0 0 1 1 1 1 Somatomedin B domain SAM_2 PF07647.12 KFM06750.1 - 9.9e-30 102.1 0.2 6.3e-16 57.9 0.1 2.8 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) TIR_2 PF13676.1 KFM06750.1 - 7.8e-20 70.9 0.0 1.1e-18 67.2 0.0 2.5 2 0 0 2 2 2 1 TIR domain SAM_1 PF00536.25 KFM06750.1 - 4.7e-18 65.1 0.1 1.1e-13 51.1 0.0 2.5 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) DUF1863 PF08937.6 KFM06750.1 - 0.044 13.8 0.2 0.18 11.8 0.0 2.1 2 1 0 2 2 2 0 MTH538 TIR-like domain (DUF1863) MFS_1 PF07690.11 KFM06751.1 - 1.1e-12 47.3 28.2 1.1e-12 47.3 19.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Na_sulph_symp PF00939.14 KFM06752.1 - 1.4e-138 462.7 21.7 1.6e-138 462.5 15.1 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 KFM06752.1 - 4.2e-16 58.4 36.0 7.3e-09 34.6 5.3 3.1 3 0 0 3 3 3 3 Citrate transporter ETRAMP PF09716.5 KFM06752.1 - 1.5 8.7 4.4 68 3.5 1.4 3.6 3 2 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Fork_head PF00250.13 KFM06753.1 - 2.2e-30 104.5 0.5 2.2e-30 104.5 0.4 2.0 2 0 0 2 2 2 1 Fork head domain GMP_PDE_delta PF05351.6 KFM06754.1 - 3.1e-81 270.7 2.8 3.5e-81 270.5 1.9 1.0 1 0 0 1 1 1 1 GMP-PDE, delta subunit IIGP PF05049.8 KFM06754.1 - 0.12 11.2 0.2 0.15 10.8 0.1 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) PIG-S PF10510.4 KFM06755.1 - 4.1e-134 448.0 0.2 4.6e-134 447.9 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein MAD PF05557.8 KFM06756.1 - 0.026 12.6 7.0 0.034 12.2 4.8 1.2 1 1 0 1 1 1 0 Mitotic checkpoint protein Tail_P2_I PF09684.5 KFM06756.1 - 0.035 13.6 0.2 0.041 13.4 0.1 1.1 1 0 0 1 1 1 0 Phage tail protein (Tail_P2_I) CALCOCO1 PF07888.6 KFM06756.1 - 0.045 12.0 8.1 0.045 12.0 5.6 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Pox_A_type_inc PF04508.7 KFM06756.1 - 0.049 13.4 0.6 0.34 10.7 0.0 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Kinesin-relat_1 PF12711.2 KFM06756.1 - 0.29 11.5 7.3 0.41 11.0 1.1 2.2 1 1 1 2 2 2 0 Kinesin motor ADIP PF11559.3 KFM06756.1 - 0.34 10.8 5.7 0.42 10.5 4.0 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3584 PF12128.3 KFM06756.1 - 0.37 8.0 7.3 0.39 7.9 5.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fib_alpha PF08702.5 KFM06756.1 - 0.8 9.8 3.5 14 5.7 0.7 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family APG6 PF04111.7 KFM06756.1 - 1.1 8.2 8.4 1.1 8.2 5.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Microtub_assoc PF07989.6 KFM06756.1 - 2.4 8.0 8.3 0.57 10.0 1.9 2.1 1 1 1 2 2 2 0 Microtubule associated DUF972 PF06156.8 KFM06756.1 - 3.9 7.8 8.1 28 5.1 5.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF972) HOOK PF05622.7 KFM06757.1 - 0.034 11.9 7.1 0.036 11.8 4.9 1.0 1 0 0 1 1 1 0 HOOK protein Uso1_p115_C PF04871.8 KFM06757.1 - 0.04 13.8 5.7 0.042 13.7 4.0 1.1 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region APG6 PF04111.7 KFM06757.1 - 0.077 12.0 6.8 0.078 12.0 4.7 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.8 KFM06757.1 - 0.12 12.7 5.6 0.14 12.4 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) KicB PF03882.9 KFM06757.1 - 0.13 10.9 2.4 0.13 10.8 1.6 1.1 1 0 0 1 1 1 0 KicB killing factor IMD PF08397.6 KFM06757.1 - 0.13 11.5 2.5 0.15 11.3 1.8 1.1 1 0 0 1 1 1 0 IRSp53/MIM homology domain GAS PF13851.1 KFM06757.1 - 0.15 11.1 6.0 0.17 11.0 4.2 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF2968 PF11180.3 KFM06757.1 - 0.57 9.5 6.7 0.61 9.4 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) UPF0449 PF15136.1 KFM06757.1 - 0.65 10.2 3.9 0.89 9.8 2.2 1.7 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 DUF342 PF03961.8 KFM06757.1 - 0.76 8.1 2.4 0.79 8.0 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TMF_TATA_bd PF12325.3 KFM06757.1 - 1.2 8.8 10.5 2.3 7.9 1.7 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Pkinase PF00069.20 KFM06758.1 - 7e-29 100.7 0.0 7.6e-29 100.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM06758.1 - 2.6e-14 52.9 0.0 3.2e-14 52.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM06758.1 - 4.4e-07 29.1 0.0 4.6e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFM06758.1 - 0.0032 17.2 0.4 0.0039 16.9 0.3 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KFM06758.1 - 0.0044 16.0 0.2 0.0049 15.9 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KFM06758.1 - 0.034 13.0 0.0 0.041 12.7 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 SH2_2 PF14633.1 KFM06760.1 - 9.5e-112 371.4 0.5 9.5e-112 371.4 0.3 2.2 2 0 0 2 2 2 1 SH2 domain YqgF PF14639.1 KFM06760.1 - 2.5e-71 238.1 0.0 8.1e-71 236.4 0.0 2.0 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 DLD PF14878.1 KFM06760.1 - 3e-54 182.0 1.2 3e-54 182.0 0.8 3.7 2 1 0 2 2 1 1 Death-like domain of SPT6 HHH_7 PF14635.1 KFM06760.1 - 2.5e-53 178.5 0.1 6e-53 177.3 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.1 KFM06760.1 - 8.5e-47 158.1 1.7 2.6e-46 156.5 1.2 1.9 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.1 KFM06760.1 - 2.1e-12 47.0 34.3 2.1e-12 47.0 23.8 8.0 8 1 2 10 10 6 2 Acidic N-terminal SPT6 Tex_N PF09371.5 KFM06760.1 - 3e-08 33.2 0.3 0.00068 18.9 0.0 3.0 3 0 0 3 3 3 2 Tex-like protein N-terminal domain SH2 PF00017.19 KFM06760.1 - 2.1e-06 27.4 0.0 5.9e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.2 KFM06760.1 - 2.9e-06 27.1 0.0 2.1e-05 24.3 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix motif S1 PF00575.18 KFM06760.1 - 4e-06 26.8 0.1 1e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 S1 RNA binding domain zf-C2H2_4 PF13894.1 KFM06760.1 - 0.12 12.7 0.3 0.38 11.2 0.2 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.10 KFM06760.1 - 0.2 11.2 0.4 0.51 9.9 0.3 1.6 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger Ribosomal_L23eN PF03939.8 KFM06761.1 - 1.7e-22 79.1 17.4 1.7e-22 79.1 12.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 KFM06761.1 - 1.5e-20 72.9 2.4 1.5e-20 72.9 1.7 1.9 2 0 0 2 2 2 1 Ribosomal protein L23 zf-ISL3 PF14690.1 KFM06761.1 - 0.063 13.3 1.3 0.14 12.2 0.9 1.6 1 0 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 M-inducer_phosp PF06617.8 KFM06761.1 - 0.1 11.6 0.5 0.11 11.4 0.3 1.2 1 0 0 1 1 1 0 M-phase inducer phosphatase TRAM_LAG1_CLN8 PF03798.11 KFM06762.1 - 5.3e-18 65.2 12.1 6.3e-18 65.0 8.4 1.0 1 0 0 1 1 1 1 TLC domain MATH PF00917.21 KFM06763.1 - 2.8e-13 50.1 0.0 3.2e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 MATH domain Smg4_UPF3 PF03467.10 KFM06763.1 - 0.065 13.2 0.0 0.073 13.0 0.0 1.1 1 0 0 1 1 1 0 Smg-4/UPF3 family FAM222A PF15258.1 KFM06764.1 - 1e-250 833.2 34.7 1.4e-250 832.7 24.1 1.2 1 0 0 1 1 1 1 Protein family of FAM222A DUF2981 PF11200.3 KFM06764.1 - 6.5 5.7 9.5 1.8 7.5 0.8 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2981) Band_7 PF01145.20 KFM06765.1 - 5.1e-19 68.8 0.1 5.1e-19 68.8 0.0 2.7 2 1 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 KFM06765.1 - 0.026 14.0 0.2 0.026 14.0 0.1 2.2 3 0 0 3 3 3 0 SPFH domain-Band 7 family PHD PF00628.24 KFM06768.1 - 1.5e-09 37.3 13.0 1.9e-07 30.6 2.9 3.2 3 0 0 3 3 3 2 PHD-finger FHA PF00498.21 KFM06768.1 - 0.0015 18.6 0.1 0.0039 17.2 0.0 1.7 1 0 0 1 1 1 1 FHA domain C1_1 PF00130.17 KFM06768.1 - 0.004 16.8 1.3 0.004 16.8 0.9 2.0 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 KFM06768.1 - 0.08 12.2 10.8 0.12 11.6 0.0 4.1 4 0 0 4 4 4 0 PHD-finger Sushi PF00084.15 KFM06769.1 - 7.2e-32 109.5 13.6 2.7e-10 40.4 1.9 3.3 3 0 0 3 3 3 3 Sushi domain (SCR repeat) CUB PF00431.15 KFM06769.1 - 2.5e-14 53.2 0.0 2.8e-13 49.9 0.0 2.3 2 0 0 2 2 2 1 CUB domain cEGF PF12662.2 KFM06769.1 - 0.52 10.0 7.7 5.6 6.6 0.1 3.7 3 1 0 3 3 3 0 Complement Clr-like EGF-like SSP160 PF06933.6 KFM06770.1 - 3.8 5.3 5.9 4.1 5.2 4.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Myosin_head PF00063.16 KFM06771.1 - 4.3e-63 213.4 0.4 1.4e-30 106.0 0.0 4.5 4 1 0 4 4 4 3 Myosin head (motor domain) Myosin_tail_1 PF01576.14 KFM06771.1 - 4.3e-34 117.4 146.3 4.3e-34 117.4 101.4 2.8 1 1 1 2 2 2 2 Myosin tail PDZ PF00595.19 KFM06771.1 - 4.9e-10 39.4 0.0 1.5e-09 37.8 0.0 2.0 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) IQ PF00612.22 KFM06771.1 - 0.00032 20.0 4.1 0.00036 19.9 0.2 2.8 2 0 0 2 2 2 1 IQ calmodulin-binding motif DUF869 PF05911.6 KFM06771.1 - 0.003 15.8 123.1 0.0073 14.6 35.0 4.0 2 1 1 3 3 3 2 Plant protein of unknown function (DUF869) AAA_22 PF13401.1 KFM06771.1 - 0.015 15.4 0.0 0.015 15.4 0.0 3.7 4 1 0 4 4 4 0 AAA domain Reo_sigmaC PF04582.7 KFM06771.1 - 0.051 12.7 43.9 0.17 11.0 1.6 6.4 2 1 3 6 6 6 0 Reovirus sigma C capsid protein AAA_29 PF13555.1 KFM06771.1 - 0.13 11.7 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 KFM06771.1 - 2 7.9 8.4 1.3 8.4 0.3 3.6 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Crystall PF00030.14 KFM06772.1 - 1.4e-60 201.1 6.8 4e-30 103.5 0.2 2.0 2 0 0 2 2 2 2 Beta/Gamma crystallin Crystall_3 PF08964.5 KFM06772.1 - 0.0027 17.4 0.9 0.37 10.5 0.1 2.7 2 2 0 2 2 2 2 Beta/Gamma crystallin NUFIP2 PF15293.1 KFM06773.1 - 4e-293 973.6 23.8 4.5e-293 973.5 16.5 1.0 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 2 Pkinase PF00069.20 KFM06774.1 - 2.7e-65 220.1 0.0 2.7e-65 220.1 0.0 2.5 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM06774.1 - 9.8e-45 152.6 1.3 1.9e-44 151.6 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KFM06774.1 - 0.0026 17.5 1.9 0.0051 16.5 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family AAA-ATPase_like PF09820.4 KFM06774.1 - 0.005 16.0 6.1 0.005 16.0 4.3 2.8 2 0 0 2 2 2 1 Predicted AAA-ATPase Abhydrolase_6 PF12697.2 KFM06775.1 - 8.9e-08 32.2 2.8 1.2e-07 31.9 1.6 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DivIC PF04977.10 KFM06776.1 - 0.01 15.2 0.3 0.016 14.7 0.2 1.2 1 0 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.10 KFM06776.1 - 0.32 10.8 1.8 0.51 10.1 1.3 1.3 1 0 0 1 1 1 0 Basic region leucine zipper DSPc PF00782.15 KFM06777.1 - 6.3e-35 119.6 0.0 2e-34 118.0 0.0 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DEK_C PF08766.6 KFM06777.1 - 2.9e-15 55.7 3.8 5.9e-15 54.7 2.7 1.6 1 0 0 1 1 1 1 DEK C terminal domain Y_phosphatase PF00102.22 KFM06777.1 - 0.01 15.2 0.0 0.03 13.6 0.0 1.8 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF2040 PF09745.4 KFM06778.1 - 2e-35 121.4 26.2 2e-35 121.4 18.1 5.7 2 1 4 6 6 6 1 Coiled-coil domain-containing protein 55 (DUF2040) SNF PF00209.13 KFM06779.1 - 2e-228 759.1 36.9 2.3e-228 758.9 25.6 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family 5HT_transporter PF03491.8 KFM06779.1 - 7.6e-06 25.9 0.6 1.7e-05 24.8 0.4 1.6 1 0 0 1 1 1 1 Serotonin (5-HT) neurotransmitter transporter, N-terminus Peptidase_C1_2 PF03051.10 KFM06780.1 - 4.5e-186 618.6 2.7 5e-186 618.4 1.8 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 KFM06780.1 - 0.00049 20.0 1.6 0.0061 16.4 0.6 2.6 2 1 0 2 2 2 1 Papain family cysteine protease Ig_2 PF13895.1 KFM06781.1 - 3.6e-18 65.4 1.2 8.7e-13 48.2 0.1 2.1 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 KFM06781.1 - 1e-16 60.5 0.8 1.1e-14 54.0 0.1 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.1 KFM06781.1 - 3.3e-15 56.3 2.7 8.7e-09 35.7 0.2 2.2 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 KFM06781.1 - 2.1e-11 43.7 5.8 4e-08 33.2 0.6 3.2 2 2 1 3 3 3 2 Immunoglobulin domain V-set PF07686.12 KFM06781.1 - 3.6e-11 42.9 4.3 5.8e-10 39.0 0.6 3.2 1 1 1 2 2 2 1 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM06781.1 - 1.3e-08 34.6 1.5 9.1e-06 25.4 0.1 2.8 2 1 0 2 2 2 2 CD80-like C2-set immunoglobulin domain C1-set PF07654.10 KFM06781.1 - 0.013 15.5 4.2 0.017 15.1 0.8 2.5 1 1 1 2 2 2 0 Immunoglobulin C1-set domain C2-set PF05790.10 KFM06781.1 - 0.055 13.4 4.8 3 7.8 0.1 3.5 2 2 2 4 4 4 0 Immunoglobulin C2-set domain Peptidase_M14 PF00246.19 KFM06782.1 - 4.1e-176 584.3 0.2 4.8e-85 285.5 0.1 3.1 3 0 0 3 3 3 3 Zinc carboxypeptidase CarboxypepD_reg PF13620.1 KFM06782.1 - 2.3e-36 123.6 9.4 7.3e-14 51.5 0.3 3.4 3 0 0 3 3 3 3 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 KFM06782.1 - 5.7e-21 74.3 1.7 5.4e-07 29.5 0.1 3.4 3 0 0 3 3 3 3 Domain of unknown function (DUF4480) PEGA PF08308.6 KFM06782.1 - 9.8e-07 28.4 0.3 0.026 14.2 0.0 3.5 3 0 0 3 3 3 2 PEGA domain phage_tail_N PF08400.5 KFM06782.1 - 0.00017 21.2 6.8 0.45 10.2 0.4 3.6 3 1 0 3 3 3 3 Prophage tail fibre N-terminal AstE_AspA PF04952.9 KFM06782.1 - 0.00085 18.2 0.1 0.019 13.8 0.0 2.4 2 0 0 2 2 2 1 Succinylglutamate desuccinylase / Aspartoacylase family V-SNARE_C PF12352.3 KFM06783.1 - 5.2e-22 77.6 3.6 5.2e-22 77.6 2.5 2.4 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KFM06783.1 - 0.0028 17.3 0.8 0.021 14.5 0.1 2.2 2 0 0 2 2 2 1 Sec20 RhoGAP PF00620.22 KFM06784.1 - 4e-48 162.8 0.0 9.8e-48 161.6 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain RhoGEF PF00621.15 KFM06784.1 - 1.7e-35 122.5 2.6 3.2e-35 121.6 1.8 1.5 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 KFM06784.1 - 5.3e-17 61.9 1.7 6.5e-17 61.6 0.3 1.9 2 0 0 2 2 2 1 PH domain C2 PF00168.25 KFM06784.1 - 6e-11 42.0 0.0 1.7e-10 40.5 0.0 1.8 1 0 0 1 1 1 1 C2 domain Tim17 PF02466.14 KFM06785.1 - 4.9e-36 123.6 3.1 5.4e-36 123.4 2.2 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family CH PF00307.26 KFM06786.1 - 6.8e-24 83.9 1.3 1.9e-23 82.5 0.1 2.5 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFM06786.1 - 9e-09 34.8 0.5 3.5e-08 32.9 0.0 2.3 2 0 0 2 2 2 1 CAMSAP CH domain IncA PF04156.9 KFM06786.1 - 0.95 9.0 112.6 0.048 13.2 2.7 7.3 3 1 4 7 7 7 0 IncA protein 7tm_1 PF00001.16 KFM06787.1 - 1.8e-63 214.0 15.9 2.3e-63 213.7 11.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM06787.1 - 4.9e-12 45.5 18.2 1.8e-08 33.8 3.2 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM06787.1 - 2.1e-05 23.7 8.2 2.1e-05 23.7 5.7 2.7 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Git3_C PF11970.3 KFM06787.1 - 0.025 14.3 0.4 0.085 12.6 0.3 2.0 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term SWIM PF04434.12 KFM06788.1 - 6.6e-07 28.6 3.4 1e-06 28.0 2.3 1.4 1 0 0 1 1 1 1 SWIM zinc finger TPR_12 PF13424.1 KFM06789.1 - 5.4e-28 96.7 16.3 4.6e-15 55.3 0.5 4.3 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 KFM06789.1 - 1.2e-15 56.0 13.4 0.0039 16.9 0.2 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.1 KFM06789.1 - 6.2e-14 51.3 18.9 0.00018 21.2 0.0 6.4 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.1 KFM06789.1 - 2e-13 49.7 23.7 8.6e-07 28.5 1.3 4.3 2 2 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 KFM06789.1 - 7.2e-12 44.3 17.1 0.0056 16.2 0.4 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFM06789.1 - 2.7e-11 43.0 11.6 0.41 11.4 0.3 6.3 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 KFM06789.1 - 8.2e-10 39.0 13.2 2.1e-05 25.0 1.5 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFM06789.1 - 1.6e-08 34.7 18.7 0.0008 19.7 0.2 4.4 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 KFM06789.1 - 3.5e-07 29.5 17.5 0.41 10.5 0.1 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFM06789.1 - 2.3e-06 26.9 11.7 0.22 11.3 0.1 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFM06789.1 - 4.6e-06 26.4 9.7 0.68 10.2 0.0 6.1 6 1 0 6 6 5 2 Tetratricopeptide repeat Apc3 PF12895.2 KFM06789.1 - 7.9e-06 25.9 9.3 0.00035 20.6 0.8 3.1 2 2 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 KFM06789.1 - 0.00075 19.7 0.0 2.4 8.8 0.0 4.2 4 0 0 4 4 3 1 Tetratricopeptide repeat Apc5 PF12862.2 KFM06789.1 - 0.0062 16.3 7.9 0.066 13.0 0.6 3.2 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 5 PPR_1 PF12854.2 KFM06789.1 - 0.1 12.1 0.1 2.1 7.8 0.0 2.5 2 0 0 2 2 2 0 PPR repeat PPR PF01535.15 KFM06789.1 - 0.17 11.9 2.2 3.2 7.9 0.1 3.6 5 0 0 5 5 4 0 PPR repeat Sec16_C PF12931.2 KFM06789.1 - 1.4 8.5 7.6 0.85 9.3 2.8 2.1 1 1 1 2 2 2 0 Sec23-binding domain of Sec16 PPR_2 PF13041.1 KFM06789.1 - 3.9 7.5 6.0 8.9 6.3 0.2 3.5 4 1 1 5 5 4 0 PPR repeat family TPR_6 PF13174.1 KFM06789.1 - 5.6 7.6 15.4 1.3e+02 3.4 0.1 6.3 6 1 1 7 7 7 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.26 KFM06790.1 - 2e-18 66.1 0.3 1.5e-11 44.1 0.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain PIG-L PF02585.12 KFM06791.1 - 2.1e-10 41.1 0.1 3.9e-10 40.3 0.0 1.4 2 0 0 2 2 2 1 GlcNAc-PI de-N-acetylase GFA PF04828.9 KFM06792.1 - 1.8e-12 47.0 1.6 1.8e-12 47.0 1.1 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_L37e PF01907.14 KFM06792.1 - 0.036 13.8 0.5 0.036 13.8 0.3 2.0 3 0 0 3 3 3 0 Ribosomal protein L37e ASFV_p27 PF06556.6 KFM06792.1 - 0.19 11.6 1.1 0.19 11.6 0.2 1.4 2 0 0 2 2 2 0 IAP-like protein p27 C-terminus FUR PF01475.14 KFM06792.1 - 2.8 7.8 5.5 1.3 8.9 0.6 2.3 2 1 0 2 2 2 0 Ferric uptake regulator family ubiquitin PF00240.18 KFM06793.1 - 1.8e-71 235.4 5.2 3.9e-35 119.0 0.3 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 KFM06793.1 - 8.1e-42 140.7 4.6 3.3e-20 71.5 0.3 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KFM06793.1 - 8.9e-15 54.7 1.3 7.3e-06 26.1 0.1 3.2 2 2 0 2 2 2 2 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KFM06793.1 - 2.7e-10 40.1 0.0 0.00067 19.3 0.0 2.0 2 0 0 2 2 2 2 Telomere stability and silencing Rad60-SLD_2 PF13881.1 KFM06793.1 - 1.1e-07 31.7 0.3 0.022 14.6 0.0 2.8 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KFM06793.1 - 2e-06 27.8 0.1 0.059 13.5 0.0 2.2 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain TUG-UBL1 PF11470.3 KFM06793.1 - 6.8e-06 25.9 0.2 0.13 12.2 0.0 2.2 2 0 0 2 2 2 2 GLUT4 regulating protein TUG DUF2870 PF11069.3 KFM06793.1 - 6.5e-05 22.8 0.0 0.58 10.2 0.0 2.7 2 2 0 2 2 2 2 Protein of unknown function (DUF2870) USP7_C2 PF14533.1 KFM06793.1 - 0.001 18.5 0.5 0.58 9.5 0.0 2.1 1 1 1 2 2 2 2 Ubiquitin-specific protease C-terminal FlgD_ig PF13860.1 KFM06793.1 - 0.0013 18.4 0.2 2.2 8.1 0.0 2.3 2 0 0 2 2 2 2 FlgD Ig-like domain Plexin_cytopl PF08337.7 KFM06793.1 - 0.0033 15.8 1.0 2 6.6 0.1 3.3 3 1 0 3 3 3 2 Plexin cytoplasmic RasGAP domain CTDII PF01556.13 KFM06793.1 - 0.013 15.3 3.4 0.94 9.4 0.2 2.3 1 1 1 2 2 2 0 DnaJ C terminal domain PI3K_rbd PF00794.13 KFM06793.1 - 0.018 15.0 0.8 4.9 7.1 0.0 2.5 2 1 0 2 2 2 0 PI3-kinase family, ras-binding domain FERM_N PF09379.5 KFM06793.1 - 0.019 15.0 0.9 15 5.7 0.1 3.4 2 2 0 2 2 2 0 FERM N-terminal domain YfmQ PF10787.4 KFM06793.1 - 0.13 11.5 0.1 14 5.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein from bacillus cereus group DUF2207 PF09972.4 KFM06793.1 - 0.21 10.1 2.1 6.9 5.1 0.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Ank_2 PF12796.2 KFM06795.1 - 1.8e-22 79.4 0.0 1.3e-10 41.4 0.0 3.8 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KFM06795.1 - 1.5e-18 65.0 0.0 1.6e-06 27.7 0.0 6.4 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.25 KFM06795.1 - 4.4e-18 64.0 1.1 6.1e-08 32.0 0.0 5.3 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.1 KFM06795.1 - 3.4e-15 55.7 0.1 0.00015 21.9 0.0 4.9 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFM06795.1 - 4.9e-11 42.8 0.1 0.004 17.6 0.0 4.9 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ion_trans PF00520.26 KFM06795.1 - 2.8e-05 23.4 19.1 2.8e-05 23.4 13.2 1.9 1 1 1 2 2 2 1 Ion transport protein Integrin_alpha2 PF08441.7 KFM06796.1 - 5.3e-47 160.7 9.1 7.8e-47 160.1 6.3 1.3 1 0 0 1 1 1 1 Integrin alpha VWA PF00092.23 KFM06796.1 - 3.1e-32 111.7 0.0 6e-32 110.7 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain FG-GAP PF01839.18 KFM06796.1 - 5.3e-18 64.1 5.8 2.1e-07 30.4 0.2 3.8 3 0 0 3 3 3 3 FG-GAP repeat VCBS PF13517.1 KFM06796.1 - 2.9e-11 43.5 0.9 4.6e-08 33.3 0.1 2.8 2 0 0 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella VWA_2 PF13519.1 KFM06796.1 - 3.8e-09 36.8 0.0 6.4e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain P2X_receptor PF00864.14 KFM06797.1 - 2.4e-172 572.8 0.1 2.8e-172 572.5 0.1 1.0 1 0 0 1 1 1 1 ATP P2X receptor Rab5ip PF07019.7 KFM06798.1 - 9.8e-25 86.5 7.6 1.2e-24 86.2 5.3 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF606 PF04657.8 KFM06798.1 - 0.014 15.4 2.5 0.021 14.8 1.7 1.3 1 1 0 1 1 1 0 Protein of unknown function, DUF606 DUF4271 PF14093.1 KFM06798.1 - 0.022 14.4 5.2 0.025 14.2 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) Peptidase_U4 PF03419.8 KFM06798.1 - 0.2 10.6 2.1 0.25 10.3 1.1 1.4 1 1 1 2 2 2 0 Sporulation factor SpoIIGA PDZ PF00595.19 KFM06799.1 - 9.9e-20 70.5 0.2 1.2e-19 70.2 0.1 1.2 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM06799.1 - 1.2e-11 44.3 0.3 1.7e-11 43.8 0.2 1.3 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.9 KFM06799.1 - 0.13 12.2 0.1 0.25 11.3 0.0 1.5 2 0 0 2 2 2 0 GRASP55/65 PDZ-like domain PQ-loop PF04193.9 KFM06800.1 - 7e-40 134.3 13.1 2e-20 72.0 1.1 2.7 2 0 0 2 2 2 2 PQ loop repeat FGGY_N PF00370.16 KFM06801.1 - 7.8e-27 94.1 0.0 1.4e-25 90.0 0.0 2.3 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 KFM06801.1 - 0.0034 16.7 0.0 0.0064 15.8 0.0 1.6 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family DUF4445 PF14574.1 KFM06801.1 - 0.033 12.4 0.0 0.053 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4445) Ank PF00023.25 KFM06802.1 - 1e-15 56.6 0.3 1e-07 31.3 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 KFM06802.1 - 4.1e-14 52.6 0.5 1.2e-09 38.3 0.2 3.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KFM06802.1 - 6.1e-11 41.4 0.4 0.0001 22.1 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 KFM06802.1 - 6e-10 39.0 0.2 0.00042 20.4 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFM06802.1 - 2.9e-07 30.8 0.3 0.015 15.7 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ion_trans PF00520.26 KFM06802.1 - 3.3e-06 26.4 20.1 1e-05 24.9 14.0 1.8 1 1 0 1 1 1 1 Ion transport protein Ank_2 PF12796.2 KFM06803.1 - 9.7e-21 73.9 6.0 2.1e-12 47.1 0.2 3.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFM06803.1 - 3.3e-17 61.3 0.3 5.7e-05 22.7 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 KFM06803.1 - 1.5e-13 49.5 0.0 0.00056 19.8 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 KFM06803.1 - 1.7e-13 50.3 0.1 0.012 15.8 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFM06803.1 - 1.5e-09 38.0 0.5 0.0092 16.4 0.0 5.0 2 1 3 5 5 5 3 Ankyrin repeats (many copies) AstE_AspA PF04952.9 KFM06804.1 - 1.6e-60 204.4 0.0 1.9e-60 204.2 0.0 1.0 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family L_HGMIC_fpl PF10242.4 KFM06806.1 - 4.2e-14 52.9 0.5 5.2e-14 52.6 0.3 1.0 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein RGS PF00615.14 KFM06807.1 - 8.1e-31 106.5 1.5 2.8e-12 46.7 0.1 3.4 3 0 0 3 3 3 3 Regulator of G protein signaling domain WD40 PF00400.27 KFM06808.1 - 3.6e-92 299.2 21.2 7.5e-13 47.8 0.1 8.5 8 1 0 8 8 8 8 WD domain, G-beta repeat NLE PF08154.7 KFM06808.1 - 7.2e-17 61.1 0.1 1.5e-16 60.1 0.0 1.6 2 0 0 2 2 2 1 NLE (NUC135) domain eIF2A PF08662.6 KFM06808.1 - 1e-07 31.8 0.1 0.28 10.8 0.0 3.8 2 2 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KFM06808.1 - 2.6e-06 25.8 3.8 0.42 8.6 0.0 4.8 3 2 2 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KFM06808.1 - 1.9e-05 23.5 5.5 0.71 8.5 0.4 4.6 2 2 1 3 3 3 3 Nup133 N terminal like PD40 PF07676.7 KFM06808.1 - 2.8e-05 23.6 1.1 0.21 11.2 0.0 4.5 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Gmad1 PF10647.4 KFM06808.1 - 0.00014 21.3 3.3 0.0011 18.3 0.1 2.8 3 0 0 3 3 3 1 Lipoprotein LpqB beta-propeller domain DUF3312 PF11768.3 KFM06808.1 - 0.00052 18.3 0.0 0.11 10.7 0.0 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF3312) Cytochrom_D1 PF02239.11 KFM06808.1 - 0.018 13.3 0.0 2.6 6.2 0.0 3.0 3 0 0 3 3 3 0 Cytochrome D1 heme domain FAD_binding_9 PF08021.6 KFM06808.1 - 0.11 12.4 0.0 0.37 10.7 0.0 1.9 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Pkinase PF00069.20 KFM06809.1 - 3.2e-70 236.2 0.0 4.6e-70 235.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF3543 PF12063.3 KFM06809.1 - 1.8e-52 177.9 4.5 2.9e-52 177.2 3.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase_Tyr PF07714.12 KFM06809.1 - 6.7e-49 166.2 0.0 1.1e-48 165.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFM06809.1 - 1.8e-06 27.1 0.0 3.9e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFM06809.1 - 7.1e-06 25.4 0.1 1.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 KFM06809.1 - 0.0018 17.2 0.0 0.0068 15.4 0.0 1.9 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KFM06809.1 - 0.0094 15.7 0.0 0.036 13.7 0.0 1.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Aldedh PF00171.17 KFM06810.1 - 5.1e-87 292.1 0.0 5.8e-87 291.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ATPase_gene1 PF09527.5 KFM06810.1 - 0.081 12.7 0.6 0.18 11.5 0.4 1.6 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit (ATPase_gene1) MatE PF01554.13 KFM06811.1 - 7.3e-45 152.4 23.7 2.2e-26 92.4 7.0 2.1 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 KFM06811.1 - 2.2e-06 27.5 10.0 2.2e-06 27.5 6.9 3.4 3 2 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain Dispanin PF04505.7 KFM06811.1 - 0.0063 16.0 0.4 0.0063 16.0 0.3 2.7 2 0 0 2 2 2 1 Interferon-induced transmembrane protein YjbE PF11106.3 KFM06811.1 - 0.14 12.1 6.7 0.058 13.3 1.8 2.2 2 0 0 2 2 2 0 Exopolysaccharide production protein YjbE MatE PF01554.13 KFM06812.1 - 4.1e-54 182.5 27.7 8e-29 100.3 7.1 2.4 2 0 0 2 2 2 2 MatE Thioredoxin_8 PF13905.1 KFM06813.1 - 6e-34 116.0 0.0 6.6e-30 103.0 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 KFM06813.1 - 1.8e-13 50.6 0.0 4.3e-11 43.0 0.0 2.6 3 0 0 3 3 3 1 Thioredoxin-like domain AhpC-TSA PF00578.16 KFM06813.1 - 2.3e-09 36.9 0.0 5.9e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_6 PF13848.1 KFM06813.1 - 1e-08 35.1 0.1 1.3e-07 31.6 0.0 2.6 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin PF00085.15 KFM06813.1 - 2.5e-08 33.5 0.0 5.9e-05 22.6 0.0 3.4 3 1 1 4 4 4 1 Thioredoxin Redoxin PF08534.5 KFM06813.1 - 1.8e-07 30.8 0.0 3.5e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.1 KFM06813.1 - 4.3e-07 29.8 0.0 1.5e-05 24.9 0.0 3.1 2 1 0 2 2 2 1 Thioredoxin-like Glutaredoxin PF00462.19 KFM06813.1 - 0.00013 21.8 0.1 0.0012 18.7 0.0 2.5 3 0 0 3 3 3 1 Glutaredoxin SCO1-SenC PF02630.9 KFM06813.1 - 0.0038 16.8 0.0 0.0092 15.6 0.0 1.6 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_9 PF14595.1 KFM06813.1 - 0.0042 16.6 0.0 2.1 7.8 0.0 3.5 2 1 0 2 2 2 1 Thioredoxin HyaE PF07449.6 KFM06813.1 - 0.005 16.7 0.2 22 5.0 0.0 3.8 4 0 0 4 4 4 0 Hydrogenase-1 expression protein HyaE NADH_4Fe-4S PF10589.4 KFM06813.1 - 0.013 14.6 0.0 0.042 13.0 0.0 1.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SpoU_methylase PF00588.14 KFM06814.1 - 8.3e-25 87.3 0.0 5.9e-15 55.3 0.0 2.2 1 1 1 2 2 2 2 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 KFM06814.1 - 1.1e-07 31.9 0.0 2.9e-07 30.5 0.0 1.7 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding Mur_ligase PF01225.20 KFM06814.1 - 0.011 15.8 0.0 4.4 7.4 0.0 2.6 2 0 0 2 2 2 0 Mur ligase family, catalytic domain Ribosomal_60s PF00428.14 KFM06814.1 - 2.5 8.5 7.0 5.7 7.4 4.8 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Glyoxalase_2 PF12681.2 KFM06815.1 - 7.3e-08 32.9 0.0 2.4e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 Glyoxalase-like domain Glyoxalase PF00903.20 KFM06815.1 - 0.00059 19.8 0.0 0.006 16.5 0.0 2.3 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 KFM06815.1 - 0.1 12.6 0.0 0.25 11.3 0.0 1.7 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TRAM_LAG1_CLN8 PF03798.11 KFM06817.1 - 2.7e-46 157.6 14.3 3e-46 157.4 9.9 1.0 1 0 0 1 1 1 1 TLC domain Vps53_N PF04100.7 KFM06818.1 - 6.6e-171 568.2 0.9 1.1e-170 567.5 0.6 1.4 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 KFM06818.1 - 1.6e-07 30.5 1.6 1.6e-07 30.5 1.1 2.0 2 1 1 3 3 3 1 Protein of unknown function N-terminal domain (DUF2450) Spc7 PF08317.6 KFM06818.1 - 0.00017 20.3 3.6 0.00035 19.3 2.5 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein Laminin_II PF06009.7 KFM06818.1 - 0.0036 17.0 5.2 0.011 15.5 3.0 2.2 2 0 0 2 2 2 1 Laminin Domain II DUF4413 PF14372.1 KFM06818.1 - 0.0047 16.8 0.5 0.046 13.7 0.0 3.0 3 1 0 3 3 2 1 Domain of unknown function (DUF4413) AAA_13 PF13166.1 KFM06818.1 - 0.01 14.3 5.9 0.015 13.7 3.6 1.6 1 1 0 1 1 1 0 AAA domain TBPIP PF07106.8 KFM06818.1 - 0.018 14.5 3.4 0.045 13.3 2.3 1.6 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Tropomyosin_1 PF12718.2 KFM06818.1 - 0.019 14.8 4.0 0.024 14.4 1.2 2.2 2 0 0 2 2 2 0 Tropomyosin like Nairo_nucleo PF02477.10 KFM06818.1 - 0.026 13.2 0.6 0.046 12.4 0.4 1.3 1 0 0 1 1 1 0 Nucleocapsid N protein MCPsignal PF00015.16 KFM06818.1 - 0.095 12.2 3.2 0.081 12.4 0.5 2.0 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain ING PF12998.2 KFM06818.1 - 0.098 12.9 8.9 0.051 13.8 3.0 2.6 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Tropomyosin PF00261.15 KFM06818.1 - 0.17 10.9 7.6 0.015 14.3 1.1 2.2 3 0 0 3 3 3 0 Tropomyosin GrpE PF01025.14 KFM06818.1 - 0.18 11.3 3.9 0.19 11.2 1.5 1.9 2 0 0 2 2 2 0 GrpE Vps51 PF08700.6 KFM06818.1 - 0.18 11.6 7.4 0.13 12.1 1.2 3.3 3 1 0 3 3 2 0 Vps51/Vps67 COG2 PF06148.6 KFM06818.1 - 0.32 10.8 6.3 0.6 9.9 2.3 3.0 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.7 KFM06818.1 - 0.33 10.7 9.8 0.61 9.9 2.2 3.8 3 2 0 3 3 3 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.17 KFM06818.1 - 0.77 9.7 9.3 0.17 11.8 2.1 2.9 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF948 PF06103.6 KFM06818.1 - 1.1 9.2 5.8 2 8.3 0.9 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) FAM101 PF15068.1 KFM06819.1 - 4.7e-72 241.7 1.7 5.2e-72 241.6 1.1 1.0 1 0 0 1 1 1 1 FAM101 family C2 PF00168.25 KFM06820.1 - 1.2e-43 146.8 0.1 6.9e-24 83.5 0.0 2.3 2 0 0 2 2 2 2 C2 domain FYVE_2 PF02318.11 KFM06820.1 - 2.5e-37 127.3 4.0 5.1e-37 126.3 2.8 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger Cript PF10235.4 KFM06820.1 - 0.0021 18.3 1.0 0.0093 16.3 0.6 2.2 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT PHD PF00628.24 KFM06820.1 - 0.073 12.7 7.4 0.19 11.4 5.1 1.8 1 0 0 1 1 1 0 PHD-finger zf-piccolo PF05715.8 KFM06820.1 - 0.083 12.9 6.8 0.2 11.7 4.7 1.7 1 0 0 1 1 1 0 Piccolo Zn-finger C1_1 PF00130.17 KFM06820.1 - 0.35 10.6 10.2 0.61 9.8 4.1 2.6 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-B_box PF00643.19 KFM06820.1 - 0.74 9.7 9.0 0.2 11.6 3.4 2.2 2 0 0 2 2 2 0 B-box zinc finger Rad51 PF08423.6 KFM06821.1 - 4.4e-34 117.5 0.2 1.4e-18 66.7 0.2 2.1 1 1 0 2 2 2 2 Rad51 AAA_25 PF13481.1 KFM06821.1 - 2.3e-08 33.6 0.1 6.4e-08 32.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 KFM06821.1 - 4.8e-05 22.5 0.1 8.8e-05 21.7 0.1 1.4 1 0 0 1 1 1 1 KaiC RecA PF00154.16 KFM06821.1 - 0.00032 19.8 0.1 0.0035 16.4 0.0 2.1 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_17 PF13207.1 KFM06821.1 - 0.0061 17.3 0.4 0.088 13.6 0.3 2.2 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.10 KFM06821.1 - 0.011 14.6 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_22 PF13401.1 KFM06821.1 - 0.014 15.5 0.3 0.055 13.6 0.2 2.3 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KFM06821.1 - 0.028 14.7 0.1 0.094 13.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KFM06821.1 - 0.1 12.4 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KFM06821.1 - 0.11 12.6 0.0 0.41 10.8 0.0 1.9 2 1 1 3 3 3 0 RNA helicase AAA PF00004.24 KFM06821.1 - 0.12 12.5 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KFM06821.1 - 0.15 10.8 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain PP2C PF00481.16 KFM06822.1 - 2.5e-64 217.1 0.2 3.2e-64 216.7 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KFM06822.1 - 0.00023 20.6 0.0 0.00078 18.9 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KFM06822.1 - 0.0042 16.8 0.9 0.52 9.9 0.1 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) zf-B_box PF00643.19 KFM06823.1 - 8.8e-10 38.3 8.9 8.8e-10 38.3 6.2 3.0 3 0 0 3 3 3 1 B-box zinc finger MATH PF00917.21 KFM06823.1 - 5.7e-07 29.7 0.0 1.8e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 MATH domain zf-C3HC4_2 PF13923.1 KFM06823.1 - 4.4e-05 23.4 18.0 4.4e-05 23.4 12.5 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM06823.1 - 0.00061 19.4 14.8 0.00061 19.4 10.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF148 PF02520.12 KFM06823.1 - 0.015 15.0 4.3 0.38 10.5 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF148 Baculo_PEP_C PF04513.7 KFM06823.1 - 0.059 13.2 5.1 0.91 9.3 1.4 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FUSC PF04632.7 KFM06823.1 - 0.086 11.2 1.3 0.16 10.4 0.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family HTH_1 PF00126.22 KFM06823.1 - 0.2 11.3 1.3 6 6.6 0.1 2.5 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family Syntaxin PF00804.20 KFM06823.1 - 0.41 10.8 12.2 1.4 9.1 3.0 3.4 3 0 0 3 3 3 0 Syntaxin MitMem_reg PF13012.1 KFM06823.1 - 6.7 6.8 12.1 3.8 7.6 1.6 3.6 3 1 0 3 3 3 0 Maintenance of mitochondrial structure and function DUF2450 PF10475.4 KFM06824.1 - 0.01 14.7 0.3 0.011 14.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) IncA PF04156.9 KFM06824.1 - 0.042 13.4 1.2 0.047 13.2 0.8 1.0 1 0 0 1 1 1 0 IncA protein KxDL PF10241.4 KFM06824.1 - 0.14 12.0 1.0 4.7 7.1 0.3 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein CENP-F_N PF10481.4 KFM06825.1 - 0.05 12.9 0.4 0.087 12.1 0.0 1.5 2 0 0 2 2 2 0 Cenp-F N-terminal domain SSFA2_C PF14723.1 KFM06825.1 - 0.053 13.2 0.1 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus DUF2146 PF10220.4 KFM06826.1 - 2e-291 969.1 0.0 2.5e-291 968.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2146) GDPD PF03009.12 KFM06827.1 - 7.7e-31 107.5 0.2 3e-23 82.6 0.1 2.0 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 KFM06827.1 - 1.1e-05 25.4 0.1 2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Yippee-Mis18 PF03226.9 KFM06828.1 - 4.9e-18 64.9 0.5 6.2e-18 64.6 0.3 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-CHY PF05495.7 KFM06828.1 - 0.009 16.1 5.5 0.031 14.4 3.8 1.8 1 1 0 1 1 1 1 CHY zinc finger NinE PF05322.6 KFM06828.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 NINE Protein AlcCBM31 PF11606.3 KFM06828.1 - 0.12 12.3 0.1 1.8 8.5 0.0 2.1 1 1 1 2 2 2 0 Family 31 carbohydrate binding protein zf-FCS PF06467.9 KFM06828.1 - 0.2 11.3 2.2 9.7 5.9 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Evr1_Alr PF04777.8 KFM06828.1 - 0.37 10.7 3.9 0.8 9.6 0.6 2.1 1 1 1 2 2 2 0 Erv1 / Alr family OB_NTP_bind PF07717.11 KFM06829.1 - 1.1e-18 67.0 0.0 2e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KFM06829.1 - 1.2e-15 57.4 0.0 2.5e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KFM06829.1 - 6.1e-13 48.4 0.0 1.3e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SE PF00437.15 KFM06829.1 - 3e-06 26.3 0.1 0.00048 19.1 0.0 2.9 2 1 0 2 2 2 1 Type II/IV secretion system protein DEAD PF00270.24 KFM06829.1 - 3.7e-06 26.5 0.0 1.2e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KFM06829.1 - 1.1e-05 25.5 0.0 2.8e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KFM06829.1 - 0.024 14.1 0.1 0.1 12.1 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_19 PF13245.1 KFM06829.1 - 0.06 13.0 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 KFM06829.1 - 0.069 12.7 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KFM06829.1 - 0.096 12.9 0.6 8.9 6.6 0.4 2.6 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 KFM06829.1 - 0.11 12.5 0.1 0.37 10.7 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 KFM06829.1 - 0.14 11.5 0.0 0.53 9.7 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family Clathrin PF00637.15 KFM06830.1 - 5.5e-211 690.6 40.2 2.3e-33 114.7 1.0 7.9 7 1 1 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.15 KFM06830.1 - 6e-47 154.7 2.0 3.7e-06 26.8 0.0 7.7 7 0 0 7 7 7 7 Clathrin propeller repeat Clathrin_H_link PF13838.1 KFM06830.1 - 3.3e-33 113.3 0.4 1.5e-32 111.2 0.3 2.3 1 0 0 1 1 1 1 Clathrin-H-link Clathrin-link PF09268.5 KFM06830.1 - 1.1e-14 53.1 0.7 3.4e-14 51.4 0.5 2.0 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.9 KFM06830.1 - 4.8e-08 32.2 4.9 1.4e-05 24.1 0.2 4.3 4 0 0 4 4 4 1 Coatomer WD associated region TPR_7 PF13176.1 KFM06830.1 - 1.2e-05 24.6 11.8 0.57 10.1 0.1 8.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFM06830.1 - 4.9e-05 23.5 16.9 9.3 7.2 0.0 10.0 10 2 2 12 12 12 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFM06830.1 - 0.00078 18.9 7.2 0.19 11.4 0.0 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFM06830.1 - 0.0045 16.8 8.8 3.9 7.6 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFM06830.1 - 0.0064 16.8 10.5 5.9 7.3 0.1 6.5 6 2 1 7 7 7 1 Tetratricopeptide repeat PTH2 PF01981.11 KFM06831.1 - 1.1e-49 166.9 0.0 1.3e-49 166.6 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF2000 PF09391.5 KFM06831.1 - 0.031 13.9 0.1 0.46 10.1 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2000) Tubulin PF00091.20 KFM06832.1 - 3.7e-62 209.9 0.1 4.9e-62 209.5 0.1 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Pkinase PF00069.20 KFM06833.1 - 9.5e-72 241.2 0.0 1.4e-71 240.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM06833.1 - 7.5e-37 126.7 0.0 9.8e-37 126.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KFM06833.1 - 9.2e-09 35.6 2.9 2.2e-08 34.4 2.0 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KFM06833.1 - 5.1e-08 32.2 0.0 1.2e-07 30.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like FliT PF05400.8 KFM06833.1 - 0.068 13.5 0.1 0.17 12.2 0.1 1.6 1 0 0 1 1 1 0 Flagellar protein FliT Kdo PF06293.9 KFM06833.1 - 0.076 12.0 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFM06833.1 - 0.15 11.7 0.0 0.42 10.2 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family zf-RING_2 PF13639.1 KFM06834.1 - 3.1e-11 42.8 9.8 8.9e-11 41.4 6.8 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFM06834.1 - 1.6e-10 40.4 6.9 3e-10 39.5 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM06834.1 - 3.8e-10 39.6 11.3 8.8e-10 38.4 7.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM06834.1 - 2e-08 33.7 11.7 4.5e-08 32.6 8.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM06834.1 - 7.3e-08 32.0 9.4 1.8e-07 30.7 6.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KFM06834.1 - 1.8e-06 27.9 10.7 5.1e-06 26.5 7.4 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KFM06834.1 - 4.7e-06 26.2 5.7 6e-06 25.8 3.1 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KFM06834.1 - 1.5e-05 24.7 11.3 3.4e-05 23.6 7.8 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 KFM06834.1 - 0.0011 18.7 3.0 0.0028 17.4 2.1 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 KFM06834.1 - 0.015 15.1 7.4 0.45 10.3 5.1 2.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 KFM06834.1 - 0.058 12.9 6.5 0.11 12.0 4.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 GAGA PF09237.6 KFM06834.1 - 0.15 11.6 1.7 6.8 6.3 0.0 2.5 2 0 0 2 2 2 0 GAGA factor UPF0547 PF10571.4 KFM06834.1 - 0.64 9.7 0.1 0.64 9.7 0.0 3.0 3 0 0 3 3 2 0 Uncharacterised protein family UPF0547 zf-Nse PF11789.3 KFM06834.1 - 0.89 9.1 8.1 1.7 8.2 5.6 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-P11 PF03854.9 KFM06834.1 - 1.8 8.1 8.1 7.2 6.1 5.5 2.2 1 1 0 1 1 1 0 P-11 zinc finger zf-RING_4 PF14570.1 KFM06834.1 - 4.5 6.9 10.1 0.35 10.4 2.6 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Macoilin PF09726.4 KFM06834.1 - 5.7 5.0 6.6 7.9 4.6 4.6 1.2 1 0 0 1 1 1 0 Transmembrane protein Med13_N PF11597.3 KFM06835.1 - 4.6e-131 437.2 6.4 7.7e-131 436.4 0.8 2.8 2 0 0 2 2 2 2 Mediator complex subunit 13 N-terminal Med13_C PF06333.7 KFM06835.1 - 7.1e-129 430.0 0.0 7.1e-129 430.0 0.0 3.1 3 1 0 3 3 3 1 Mediator complex subunit 13 C-terminal INTS2 PF14750.1 KFM06836.1 - 0 1552.1 22.2 0 1551.8 15.4 1.0 1 0 0 1 1 1 1 Integrator complex subunit 2 Helicase_C_2 PF13307.1 KFM06837.1 - 9.8e-53 178.5 0.0 2.3e-52 177.3 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 KFM06837.1 - 6.1e-46 155.9 0.3 6.1e-46 155.9 0.2 3.0 4 0 0 4 4 4 1 DEAD_2 DEAD PF00270.24 KFM06837.1 - 1.1e-06 28.1 0.0 3.9e-06 26.4 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KFM06837.1 - 0.0038 17.0 0.0 1.1 9.1 0.0 3.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T-box PF00907.17 KFM06838.1 - 8.1e-55 185.1 0.1 7e-54 182.1 0.1 2.1 1 1 0 1 1 1 1 T-box BCAS3 PF12490.3 KFM06839.1 - 5.6e-31 107.7 0.0 1.4e-30 106.4 0.0 1.5 1 1 0 1 1 1 1 Breast carcinoma amplified sequence 3 WD40 PF00400.27 KFM06839.1 - 8.1e-06 25.5 0.5 0.00092 19.0 0.0 3.6 3 0 0 3 3 3 1 WD domain, G-beta repeat PP2C PF00481.16 KFM06840.1 - 2.2e-59 200.9 0.0 3e-59 200.4 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KFM06840.1 - 0.0012 18.3 0.0 0.048 13.0 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C TPR_12 PF13424.1 KFM06841.1 - 4e-23 81.1 23.0 6.6e-09 35.5 0.7 7.2 4 2 4 8 8 8 7 Tetratricopeptide repeat TPR_10 PF13374.1 KFM06841.1 - 4.9e-16 58.0 2.9 4.1e-05 23.3 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFM06841.1 - 1.8e-08 33.5 3.2 0.0047 16.6 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFM06841.1 - 8.3e-06 25.1 23.9 0.00025 20.5 0.1 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.1 KFM06841.1 - 8.8e-06 25.2 21.5 0.0025 17.4 2.0 6.3 3 3 3 6 6 6 3 TPR repeat TPR_2 PF07719.12 KFM06841.1 - 3.7e-05 23.3 15.4 2.6 8.1 0.1 7.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFM06841.1 - 9.5 6.2 18.3 2.8 7.9 0.1 6.5 8 0 0 8 8 8 0 Tetratricopeptide repeat DUF4208 PF13907.1 KFM06842.1 - 1.4e-22 79.7 3.1 1.6e-22 79.5 2.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) CRAL_TRIO_N PF03765.10 KFM06842.1 - 0.064 13.3 2.9 0.068 13.3 0.6 2.0 2 0 0 2 2 2 0 CRAL/TRIO, N-terminal domain UCH PF00443.24 KFM06843.1 - 1.8e-73 246.9 0.0 3.6e-73 246.0 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 KFM06843.1 - 3.3e-36 123.6 1.4 5.6e-36 122.9 0.1 2.2 2 0 0 2 2 2 1 DUSP domain UCH_1 PF13423.1 KFM06843.1 - 1.6e-18 67.1 1.0 8.9e-10 38.4 0.4 3.4 2 2 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase EF-hand_1 PF00036.27 KFM06843.1 - 4.4e-09 34.9 1.5 0.00078 18.5 0.1 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 KFM06843.1 - 5.4e-09 35.1 1.0 0.029 14.2 0.0 4.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.1 KFM06843.1 - 5.5e-09 34.9 2.5 0.00014 21.0 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 KFM06843.1 - 1.6e-08 34.5 6.3 3.6e-06 26.9 0.8 3.2 2 1 0 3 3 3 2 EF-hand domain pair Ubiquitin_3 PF14836.1 KFM06843.1 - 4e-06 26.3 0.1 9.7e-06 25.1 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain EF-hand_8 PF13833.1 KFM06843.1 - 7.1e-06 25.5 4.6 0.23 11.1 0.1 3.5 3 0 0 3 3 3 2 EF-hand domain pair Ubiquitin_2 PF14560.1 KFM06843.1 - 5.7e-05 23.2 3.1 0.001 19.2 0.2 3.0 3 0 0 3 3 3 1 Ubiquitin-like domain Carb_anhydrase PF00194.16 KFM06844.1 - 8.5e-74 247.7 0.3 1e-73 247.5 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase 7tm_1 PF00001.16 KFM06845.1 - 1.1e-31 109.8 18.3 1.3e-31 109.7 12.7 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) ParcG PF10274.4 KFM06846.1 - 0.0043 16.9 0.0 0.0049 16.7 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein Rz1 PF06085.6 KFM06846.1 - 0.038 13.3 1.1 0.045 13.1 0.1 1.7 2 0 0 2 2 2 0 Lipoprotein Rz1 precursor Myosin_head PF00063.16 KFM06847.1 - 1.5e-192 641.3 0.5 1.8e-192 641.0 0.4 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.22 KFM06847.1 - 0.00014 21.2 14.2 0.0014 18.0 0.9 3.3 3 0 0 3 3 3 2 IQ calmodulin-binding motif AAA_22 PF13401.1 KFM06847.1 - 0.00067 19.7 0.5 0.0047 17.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFM06847.1 - 0.003 17.5 0.1 0.22 11.4 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain GWT1 PF06423.7 KFM06848.1 - 3.5e-35 121.0 2.9 3.5e-35 121.0 2.0 2.5 3 0 0 3 3 3 1 GWT1 DUF998 PF06197.8 KFM06848.1 - 0.1 11.8 9.8 0.33 10.2 6.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF998) adh_short PF00106.20 KFM06850.1 - 5.3e-15 55.7 0.0 7.1e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFM06850.1 - 2.3e-09 37.3 0.0 2.7e-09 37.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFM06850.1 - 0.0014 18.3 0.0 0.0045 16.6 0.0 1.7 2 0 0 2 2 2 1 KR domain SpoU_methylase PF00588.14 KFM06851.1 - 3.1e-31 108.1 0.0 4.2e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 KFM06851.1 - 2.2e-11 43.7 0.0 3.6e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding DUF4177 PF13783.1 KFM06851.1 - 0.042 13.4 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4177) AATF-Che1 PF13339.1 KFM06852.1 - 3.4e-37 127.5 0.9 3.4e-37 127.5 0.6 2.7 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor TRAUB PF08164.7 KFM06852.1 - 1.5e-25 89.0 0.2 1.5e-25 89.0 0.2 2.2 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal TraI PF07057.6 KFM06852.1 - 0.00022 21.2 0.1 0.4 10.6 0.0 3.4 3 0 0 3 3 3 2 DNA helicase TraI LMBR1 PF04791.11 KFM06852.1 - 0.17 10.4 0.3 0.3 9.6 0.2 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein SWIRM PF04433.12 KFM06854.1 - 4.1e-15 55.6 0.0 1.3e-14 54.1 0.0 1.9 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 KFM06854.1 - 8.8e-10 38.4 0.3 2e-09 37.3 0.1 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFM06854.1 - 3e-05 24.0 0.4 0.00015 21.7 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain ZZ PF00569.12 KFM06854.1 - 0.021 14.3 2.3 0.043 13.3 1.6 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type RPA_C PF08784.6 KFM06854.1 - 0.13 12.7 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 Replication protein A C terminal Pedibin PF08182.6 KFM06854.1 - 2.2 7.8 7.4 0.74 9.3 0.1 2.4 2 0 0 2 2 2 0 Pedibin/Hym-346 family EF-hand_4 PF12763.2 KFM06855.1 - 0.013 15.2 0.0 0.037 13.7 0.0 1.8 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand zf-rbx1 PF12678.2 KFM06855.1 - 0.05 13.7 0.1 0.12 12.5 0.1 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger DEAD PF00270.24 KFM06856.1 - 2.5e-38 131.2 0.0 9.3e-38 129.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFM06856.1 - 3.4e-26 90.9 1.1 6.9e-26 89.9 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFM06856.1 - 1.3e-06 28.3 1.1 9.6e-06 25.5 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KFM06856.1 - 6e-06 25.2 0.0 1.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C_2 PF13307.1 KFM06856.1 - 0.002 18.0 0.0 0.005 16.8 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain AAA_19 PF13245.1 KFM06856.1 - 0.011 15.5 0.0 0.037 13.7 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain HNF-1B_C PF04812.8 KFM06857.1 - 2.5e-106 354.4 39.5 3.8e-106 353.8 27.4 1.3 1 0 0 1 1 1 1 Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus HNF-1_N PF04814.8 KFM06857.1 - 6.3e-46 156.7 2.6 6.3e-46 156.7 1.8 2.0 2 0 0 2 2 2 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus Homeobox PF00046.24 KFM06857.1 - 7.7e-07 28.6 0.9 5.3e-06 25.9 0.6 2.4 1 1 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFM06857.1 - 0.067 12.9 0.0 0.41 10.3 0.0 2.4 2 1 0 2 2 2 0 Homeobox KN domain HTH_5 PF01022.15 KFM06857.1 - 0.53 9.9 0.1 0.53 9.9 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family DUF4042 PF13251.1 KFM06858.1 - 3.5e-70 235.1 4.2 1.7e-68 229.7 0.1 4.4 4 0 0 4 4 4 1 Domain of unknown function (DUF4042) HEAT_2 PF13646.1 KFM06858.1 - 9e-29 99.5 5.9 2.4e-08 34.1 0.0 7.5 4 1 4 8 8 8 6 HEAT repeats HEAT PF02985.17 KFM06858.1 - 8.1e-17 59.7 17.4 0.00061 19.6 0.0 10.3 11 0 0 11 11 11 5 HEAT repeat HEAT_EZ PF13513.1 KFM06858.1 - 8.3e-17 61.1 13.6 0.0063 16.9 0.3 8.7 9 0 0 9 9 9 5 HEAT-like repeat Adaptin_N PF01602.15 KFM06858.1 - 2.3e-05 22.9 12.5 0.13 10.5 0.2 5.0 4 3 2 6 6 6 3 Adaptin N terminal region FANCI_S2 PF14676.1 KFM06858.1 - 0.0039 17.1 5.8 0.97 9.3 0.0 3.8 4 0 0 4 4 4 1 FANCI solenoid 2 HEAT_PBS PF03130.11 KFM06858.1 - 0.016 15.5 8.4 3.2 8.4 0.0 6.4 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat Arm PF00514.18 KFM06858.1 - 0.02 14.7 23.0 0.51 10.2 0.1 8.2 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat Dynein_light PF01221.13 KFM06859.1 - 4.3e-46 154.8 1.7 4.7e-46 154.7 1.2 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 TraH PF06122.6 KFM06859.1 - 0.034 12.9 0.1 0.038 12.7 0.0 1.0 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein HEXIM PF15313.1 KFM06859.1 - 0.05 13.7 0.5 0.06 13.5 0.3 1.1 1 0 0 1 1 1 0 Hexamethylene bis-acetamide-inducible protein WIYLD PF10440.4 KFM06859.1 - 0.054 13.4 0.0 0.074 13.0 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-binding WIYLD domain HTH_33 PF13592.1 KFM06859.1 - 0.068 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix Ground-like PF04155.13 KFM06859.1 - 0.079 13.2 0.1 0.098 12.9 0.1 1.3 1 1 0 1 1 1 0 Ground-like domain UCH PF00443.24 KFM06859.1 - 0.084 11.9 0.1 0.09 11.8 0.1 1.0 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Ectatomin PF06457.6 KFM06859.1 - 0.13 12.0 0.2 0.21 11.3 0.2 1.4 1 0 0 1 1 1 0 Ectatomin SpoIIIAH PF12685.2 KFM06859.1 - 0.26 10.7 2.2 0.32 10.4 1.6 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein zf-C2H2 PF00096.21 KFM06860.1 - 5.3e-19 67.3 52.7 0.00023 21.3 1.5 6.8 7 0 0 7 7 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM06860.1 - 3.5e-16 58.2 51.7 0.00021 21.3 0.8 6.9 7 0 0 7 7 6 5 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFM06860.1 - 3.6e-16 58.5 60.3 1.1e-06 28.6 2.0 8.6 9 0 0 9 9 8 5 Zinc-finger double domain zf-Di19 PF05605.7 KFM06860.1 - 0.00055 20.0 31.6 0.28 11.3 4.6 4.5 4 0 0 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.10 KFM06860.1 - 0.022 14.5 2.3 0.022 14.5 1.6 6.9 4 2 3 7 7 7 0 BED zinc finger Med15 PF09606.5 KFM06860.1 - 0.038 12.2 25.0 0.061 11.5 17.3 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DZR PF12773.2 KFM06860.1 - 0.11 12.3 20.9 0.65 9.8 0.5 4.7 3 1 0 3 3 3 0 Double zinc ribbon zf-met PF12874.2 KFM06860.1 - 0.17 12.0 0.2 0.17 12.0 0.1 6.5 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFM06860.1 - 0.31 11.2 31.3 0.094 12.8 0.8 6.0 7 0 0 7 7 6 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFM06860.1 - 0.36 10.9 34.7 1 9.4 0.0 6.3 2 1 3 6 6 5 0 C2H2 type zinc-finger (2 copies) XPA_N PF01286.13 KFM06860.1 - 0.54 9.9 0.1 0.54 9.9 0.0 5.4 7 0 0 7 7 6 0 XPA protein N-terminal TrbI PF03743.9 KFM06860.1 - 0.78 9.2 8.2 1 8.8 2.1 2.4 2 0 0 2 2 2 0 Bacterial conjugation TrbI-like protein BAF1_ABF1 PF04684.8 KFM06860.1 - 1.5 7.6 10.6 2.3 6.9 7.4 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SIR2 PF02146.12 KFM06860.1 - 4 7.1 19.6 0.098 12.3 1.8 3.0 1 1 2 3 3 3 0 Sir2 family CUE PF02845.11 KFM06861.1 - 2.1e-15 55.8 0.2 4.6e-15 54.7 0.1 1.6 1 0 0 1 1 1 1 CUE domain MRP-S23 PF10484.4 KFM06862.1 - 9.4e-09 35.2 0.0 1e-08 35.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S23 RRM_6 PF14259.1 KFM06863.1 - 0.0056 16.6 0.1 0.013 15.4 0.1 1.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFM06863.1 - 0.0074 15.9 0.4 0.014 15.0 0.1 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NID PF07292.8 KFM06863.1 - 0.032 14.2 0.0 0.043 13.8 0.0 1.1 1 0 0 1 1 1 0 Nmi/IFP 35 domain (NID) TUDOR PF00567.19 KFM06864.1 - 4.7e-21 74.8 0.0 1.3e-20 73.4 0.0 1.8 2 0 0 2 2 2 1 Tudor domain KH_1 PF00013.24 KFM06864.1 - 6.4e-13 48.1 0.0 1.3e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 KFM06864.1 - 1e-05 25.0 0.0 2.8e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 KH domain Agenet PF05641.7 KFM06864.1 - 0.011 15.8 0.0 0.038 14.1 0.0 1.9 1 0 0 1 1 1 0 Agenet domain KH_4 PF13083.1 KFM06864.1 - 0.11 12.1 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 KH domain RasGAP PF00616.14 KFM06865.1 - 5.1e-42 143.7 0.9 1.4e-41 142.3 0.1 2.3 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 KFM06865.1 - 2.5e-21 76.1 0.0 8.6e-21 74.3 0.0 2.0 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 KFM06865.1 - 0.0047 16.4 0.0 0.055 12.9 0.0 2.7 2 0 0 2 2 2 1 CRAL/TRIO domain DUF1659 PF07872.6 KFM06865.1 - 0.083 12.5 0.0 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1659) EVI2A PF05399.6 KFM06866.1 - 3.2e-93 311.1 10.5 3.7e-93 310.9 7.3 1.0 1 0 0 1 1 1 1 Ectropic viral integration site 2A protein (EVI2A) DUF3753 PF12575.3 KFM06866.1 - 0.0053 16.5 1.2 0.019 14.7 0.8 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3753) Peptidase_M56 PF05569.6 KFM06866.1 - 0.013 14.4 0.2 0.019 13.9 0.1 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 T4_deiodinase PF00837.12 KFM06866.1 - 0.071 12.0 0.0 1.8 7.5 0.0 2.2 2 0 0 2 2 2 0 Iodothyronine deiodinase DUF912 PF06024.7 KFM06866.1 - 0.087 12.8 2.9 0.21 11.6 0.2 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4179 PF13786.1 KFM06866.1 - 0.095 12.9 6.0 1.4 9.1 0.1 2.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4179) Orbi_NS3 PF01616.11 KFM06866.1 - 0.13 11.1 4.0 0.21 10.5 0.0 2.3 2 0 0 2 2 2 0 Orbivirus NS3 Synaptobrevin PF00957.16 KFM06866.1 - 0.75 9.4 3.9 3.4 7.3 0.1 2.6 2 0 0 2 2 2 0 Synaptobrevin ETRAMP PF09716.5 KFM06866.1 - 1.2 9.1 6.2 1.3 9.0 0.9 2.5 1 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) TMEM154 PF15102.1 KFM06866.1 - 1.9 8.1 9.2 0.12 12.0 2.3 2.0 2 1 0 2 2 2 0 TMEM154 protein family LRR_8 PF13855.1 KFM06867.1 - 6.3e-19 67.4 20.0 4.6e-11 42.2 0.6 3.7 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KFM06867.1 - 4.1e-17 61.3 26.2 5e-07 29.1 1.2 5.1 2 2 4 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM06867.1 - 6.5e-12 43.7 26.5 0.041 13.9 0.0 8.6 7 2 2 9 9 9 5 Leucine Rich Repeat LRR_6 PF13516.1 KFM06867.1 - 4.8e-09 35.3 18.8 1.5 9.1 0.1 7.1 7 0 0 7 7 7 5 Leucine Rich repeat LRR_7 PF13504.1 KFM06867.1 - 3.2e-08 32.4 19.0 0.24 11.7 0.0 7.7 8 0 0 8 8 8 3 Leucine rich repeat LRRNT PF01462.13 KFM06867.1 - 3.3e-08 32.8 2.7 7.4e-08 31.6 1.9 1.7 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain KaiB PF07689.7 KFM06867.1 - 0.013 14.9 0.2 7.2 6.1 0.1 2.9 3 0 0 3 3 3 0 KaiB domain SERTA PF06031.8 KFM06867.1 - 0.086 12.1 0.4 0.32 10.3 0.3 2.0 1 0 0 1 1 1 0 SERTA motif Pkinase_Tyr PF07714.12 KFM06868.1 - 3.4e-50 170.5 0.0 6.8e-50 169.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM06868.1 - 3.5e-43 147.6 0.0 6.6e-43 146.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain KSR1-SAM PF13543.1 KFM06868.1 - 6.1e-22 77.7 0.3 1e-21 77.0 0.2 1.4 1 0 0 1 1 1 1 SAM like domain present in kinase suppressor RAS 1 Kinase-like PF14531.1 KFM06868.1 - 5.3e-05 22.3 0.0 9.3e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like C1_1 PF00130.17 KFM06868.1 - 0.00038 20.1 12.4 0.00074 19.2 8.6 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RIO1 PF01163.17 KFM06868.1 - 0.003 16.9 0.0 0.0051 16.1 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KFM06868.1 - 0.064 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-RING-like PF08746.6 KFM06868.1 - 0.11 12.4 7.9 0.3 11.1 5.5 1.7 1 0 0 1 1 1 0 RING-like domain NO_synthase PF02898.10 KFM06869.1 - 2.4e-219 727.4 0.4 3.2e-219 727.0 0.3 1.2 1 0 0 1 1 1 1 Nitric oxide synthase, oxygenase domain FAD_binding_1 PF00667.15 KFM06869.1 - 1.1e-64 217.8 0.0 1.9e-64 217.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KFM06869.1 - 1.8e-43 147.9 0.0 4e-43 146.8 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KFM06869.1 - 3.3e-22 79.1 0.1 9.8e-22 77.5 0.1 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Complex1_LYR PF05347.10 KFM06870.1 - 6.1e-15 54.7 1.0 6.9e-15 54.5 0.7 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KFM06870.1 - 1.7e-14 53.7 0.4 2.1e-14 53.4 0.3 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Sigma70_r4 PF04545.11 KFM06870.1 - 0.037 13.3 0.7 6.3 6.1 0.0 2.3 2 1 0 2 2 2 0 Sigma-70, region 4 DUF982 PF06169.7 KFM06870.1 - 0.12 12.1 0.1 0.14 11.9 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF982) DUF1320 PF07030.7 KFM06870.1 - 0.46 10.2 2.0 6.2 6.5 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1320) DUF2781 PF10914.3 KFM06871.1 - 1.5e-20 73.5 2.6 1.5e-20 73.4 1.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) IFT20 PF14931.1 KFM06872.1 - 5.1e-32 110.2 9.0 5.6e-32 110.1 6.2 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 HRDC PF00570.18 KFM06872.1 - 0.041 13.6 1.0 0.055 13.1 0.7 1.2 1 0 0 1 1 1 0 HRDC domain YebO PF13974.1 KFM06872.1 - 8.8 6.1 7.3 4.5 7.1 3.3 1.8 1 1 1 2 2 2 0 YebO-like protein BTB_2 PF02214.17 KFM06873.1 - 2.1e-20 72.7 0.0 4e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KFM06873.1 - 4.4e-06 26.6 0.0 9.4e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain RUN PF02759.14 KFM06874.1 - 5.9e-38 129.6 0.0 2.7e-37 127.4 0.0 2.2 2 0 0 2 2 2 1 RUN domain RabGAP-TBC PF00566.13 KFM06874.1 - 1.3e-31 109.7 9.1 7.9e-30 103.9 3.8 2.7 2 0 0 2 2 2 2 Rab-GTPase-TBC domain DUF3548 PF12068.3 KFM06874.1 - 1.5e-06 27.6 0.0 0.0011 18.3 0.0 2.8 2 1 1 3 3 3 2 Domain of unknown function (DUF3548) HLH PF00010.21 KFM06875.1 - 8.1e-13 47.8 2.0 2.2e-12 46.4 1.4 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Sipho_Gp157 PF05565.6 KFM06875.1 - 0.0038 16.8 2.8 0.0071 15.9 1.9 1.4 1 0 0 1 1 1 1 Siphovirus Gp157 DDE_Tnp_IS66 PF03050.9 KFM06875.1 - 0.098 11.8 2.2 0.16 11.1 1.5 1.2 1 0 0 1 1 1 0 Transposase IS66 family IncA PF04156.9 KFM06875.1 - 4.5 6.8 6.6 9.5 5.7 4.5 1.5 1 0 0 1 1 1 0 IncA protein WD40 PF00400.27 KFM06876.1 - 3.8e-87 283.3 18.6 4.2e-14 51.7 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KFM06876.1 - 1.7e-12 46.2 12.6 0.0037 15.4 0.0 6.5 2 2 5 7 7 7 5 Nucleoporin Nup120/160 LisH PF08513.6 KFM06876.1 - 9.3e-07 28.3 0.4 2.2e-06 27.2 0.3 1.7 1 0 0 1 1 1 1 LisH Nucleoporin_N PF08801.6 KFM06876.1 - 9e-06 24.6 0.4 0.72 8.5 0.0 4.5 1 1 4 5 5 5 2 Nup133 N terminal like Rav1p_C PF12234.3 KFM06876.1 - 0.012 13.8 0.1 0.048 11.8 0.0 1.8 2 0 0 2 2 2 0 RAVE protein 1 C terminal Pox_A_type_inc PF04508.7 KFM06876.1 - 0.013 15.1 0.4 0.036 13.8 0.3 1.8 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DUF904 PF06005.7 KFM06876.1 - 0.12 12.6 1.5 0.21 11.9 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) CLU PF13236.1 KFM06877.1 - 2.2e-91 305.1 0.0 3.8e-91 304.4 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 KFM06877.1 - 5.2e-58 195.7 0.1 1.3e-57 194.4 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.1 KFM06877.1 - 5.8e-27 93.6 0.2 5.8e-27 93.6 0.1 2.8 3 0 0 3 3 3 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.1 KFM06877.1 - 1.1e-17 63.6 9.6 1.5e-08 34.4 0.3 3.7 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 KFM06877.1 - 2.1e-11 43.3 4.0 0.00073 19.3 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFM06877.1 - 0.0073 16.0 0.7 2.8 7.9 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 KFM06877.1 - 0.015 14.9 6.5 0.7 9.5 0.2 3.1 2 1 1 3 3 3 0 TPR repeat DUF727 PF05303.7 KFM06877.1 - 0.022 14.5 0.0 0.081 12.7 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF727) TPR_2 PF07719.12 KFM06877.1 - 0.23 11.4 2.8 2.6 8.1 0.1 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat CCDC92 PF14916.1 KFM06878.1 - 1.9e-15 56.1 13.7 1.9e-15 56.1 9.5 2.2 1 1 0 2 2 2 1 Coiled-coil domain of unknown function DUF2702 PF10863.3 KFM06878.1 - 0.1 12.3 1.9 0.21 11.2 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2702) DivIC PF04977.10 KFM06878.1 - 1.9 8.0 18.3 12 5.4 2.7 3.3 1 1 2 3 3 3 0 Septum formation initiator Tox-ODYAM1 PF15642.1 KFM06878.1 - 2.5 6.6 9.0 2.8 6.4 6.3 1.2 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus FlaC_arch PF05377.6 KFM06878.1 - 2.7 7.9 7.3 4.6 7.2 1.1 3.0 2 2 0 2 2 2 0 Flagella accessory protein C (FlaC) TPD52 PF04201.10 KFM06878.1 - 3.1 7.4 17.5 1.1 8.9 6.0 2.6 1 1 1 2 2 2 0 Tumour protein D52 family DUF3153 PF11353.3 KFM06878.1 - 3.1 7.1 6.3 6.4 6.1 0.6 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3153) FlxA PF14282.1 KFM06878.1 - 3.6 7.5 16.0 5.4 7.0 0.7 2.5 1 1 1 2 2 2 0 FlxA-like protein TTKRSYEDQ PF10212.4 KFM06878.1 - 7.3 5.3 15.6 0.25 10.2 5.8 1.8 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein DUF1515 PF07439.6 KFM06878.1 - 9.9 6.0 6.4 3.4 7.4 1.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Rap_GAP PF02145.10 KFM06879.1 - 6.5e-64 214.7 0.0 1.3e-63 213.8 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP GoLoco PF02188.12 KFM06879.1 - 0.018 14.3 0.0 0.037 13.3 0.0 1.5 1 0 0 1 1 1 0 GoLoco motif WSC PF01822.14 KFM06881.1 - 1.5e-31 108.1 20.1 3.9e-20 71.5 7.1 2.3 2 0 0 2 2 2 2 WSC domain Sulfotransfer_1 PF00685.22 KFM06881.1 - 1.7e-08 34.1 0.2 3.2e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 Sulfotransferase domain DUF164 PF02591.10 KFM06882.1 - 1.5 8.7 0.0 1.5 8.7 0.0 3.9 4 1 1 5 5 5 0 Putative zinc ribbon domain Na_sulph_symp PF00939.14 KFM06884.1 - 4.2e-117 391.9 26.0 5.1e-117 391.6 18.0 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 KFM06884.1 - 1.2e-16 60.3 38.8 2.4e-06 26.3 8.1 3.1 3 0 0 3 3 3 3 Citrate transporter UPF0121 PF03661.8 KFM06884.1 - 1 8.5 9.2 0.67 9.0 4.7 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0121) Med31 PF05669.7 KFM06885.1 - 5.2e-43 144.9 9.2 6.9e-43 144.5 6.4 1.1 1 0 0 1 1 1 1 SOH1 DUF953 PF06110.6 KFM06886.1 - 9.5e-41 137.9 0.1 1.1e-40 137.8 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_2 PF13098.1 KFM06886.1 - 0.026 14.7 0.2 0.04 14.1 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain DDHD PF02862.12 KFM06887.1 - 2.1e-47 161.8 0.0 4.5e-47 160.7 0.0 1.6 1 0 0 1 1 1 1 DDHD domain LNS2 PF08235.8 KFM06887.1 - 1.2e-37 128.9 0.1 2e-37 128.1 0.1 1.4 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Acid_phosphat_B PF03767.9 KFM06887.1 - 0.013 14.9 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) DUF1466 PF07326.6 KFM06888.1 - 1.9e-10 40.4 0.3 2e-10 40.3 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1466) NanE PF04131.9 KFM06888.1 - 0.12 11.3 0.0 0.13 11.2 0.0 1.0 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase DUF1466 PF07326.6 KFM06889.1 - 9.5e-15 54.5 1.7 1.1e-14 54.3 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1466) F-box-like PF12937.2 KFM06890.1 - 3.3e-09 36.3 2.6 3.3e-09 36.3 1.8 2.9 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KFM06890.1 - 8.6e-06 25.2 0.3 8.6e-06 25.2 0.2 2.6 2 0 0 2 2 2 1 F-box domain Tektin PF03148.9 KFM06891.1 - 2e-136 454.5 35.7 2.4e-136 454.3 24.7 1.0 1 0 0 1 1 1 1 Tektin family Bacillus_HBL PF05791.6 KFM06891.1 - 1.1 8.5 20.1 0.15 11.4 0.3 3.9 3 1 1 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) AAA_13 PF13166.1 KFM06891.1 - 7.9 4.7 32.1 40 2.4 1.4 3.6 1 1 1 2 2 2 0 AAA domain CH PF00307.26 KFM06892.1 - 2.2e-17 63.0 0.1 3.8e-17 62.3 0.1 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFM06892.1 - 8.7e-06 25.3 0.1 1.9e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain zf-C2H2 PF00096.21 KFM06893.1 - 0.16 12.4 5.5 0.37 11.2 0.1 2.3 1 1 1 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM06893.1 - 0.26 11.7 1.8 6.1 7.4 0.0 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger KH_1 PF00013.24 KFM06894.1 - 1.3e-36 124.0 13.7 1.9e-16 59.4 0.3 4.1 3 1 1 4 4 4 4 KH domain KH_3 PF13014.1 KFM06894.1 - 3.3e-29 99.9 15.3 8.2e-13 47.6 2.0 3.6 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KFM06894.1 - 1.2e-12 47.1 4.9 0.00014 21.3 0.0 3.9 3 1 1 4 4 4 3 KH domain KH_4 PF13083.1 KFM06894.1 - 5.4e-06 25.9 3.1 0.59 9.8 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 KFM06894.1 - 0.0016 18.1 3.2 2.2 8.1 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain Pkinase PF00069.20 KFM06895.1 - 5e-52 176.6 0.0 5.7e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM06895.1 - 4.4e-49 166.8 0.0 5.5e-49 166.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFM06895.1 - 0.045 13.4 0.0 0.32 10.6 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KFM06895.1 - 0.058 12.3 0.0 0.099 11.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Homeobox PF00046.24 KFM06897.1 - 4.1e-19 67.9 7.6 4.9e-19 67.7 5.2 1.1 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFM06897.1 - 0.00017 21.2 2.2 0.00027 20.5 1.5 1.3 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 KFM06897.1 - 0.0033 16.4 0.1 0.0042 16.1 0.0 1.2 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox PF00046.24 KFM06899.1 - 3e-20 71.5 6.7 3.2e-20 71.4 4.7 1.0 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 KFM06899.1 - 0.00047 19.1 0.1 0.00047 19.1 0.1 1.2 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.6 KFM06899.1 - 0.018 14.6 1.9 0.03 14.0 1.3 1.3 1 0 0 1 1 1 0 Homeobox KN domain HTH_23 PF13384.1 KFM06899.1 - 0.12 12.1 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain DUF3528 PF12045.3 KFM06900.1 - 1.2e-55 187.5 2.9 2.1e-55 186.7 2.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3528) Homeobox PF00046.24 KFM06900.1 - 6.4e-20 70.5 8.1 1.1e-19 69.8 5.6 1.4 1 0 0 1 1 1 1 Homeobox domain Baculo_p74_N PF08404.5 KFM06900.1 - 0.0035 16.1 0.3 0.0054 15.5 0.2 1.3 1 0 0 1 1 1 1 Baculoviridae P74 N-terminal Homeobox_KN PF05920.6 KFM06900.1 - 0.1 12.3 0.3 0.22 11.2 0.2 1.6 1 0 0 1 1 1 0 Homeobox KN domain Homeobox PF00046.24 KFM06901.1 - 9.7e-22 76.3 5.9 2.6e-21 74.9 4.1 1.8 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFM06901.1 - 0.015 14.9 1.1 0.053 13.2 0.3 2.3 2 0 0 2 2 2 0 Homeobox KN domain Mito_fiss_reg PF05308.6 KFM06901.1 - 6.6 6.0 14.5 8.8 5.6 9.6 1.5 1 1 0 1 1 1 0 Mitochondrial fission regulator Homeobox PF00046.24 KFM06902.1 - 7.4e-20 70.3 3.9 7.4e-20 70.3 2.7 1.6 2 0 0 2 2 2 1 Homeobox domain DUF2380 PF09533.5 KFM06902.1 - 0.0033 16.8 0.0 0.0053 16.1 0.0 1.3 1 0 0 1 1 1 1 Predicted lipoprotein of unknown function (DUF2380) Homeobox_KN PF05920.6 KFM06902.1 - 0.02 14.5 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Homeobox KN domain Nucleoplasmin PF03066.10 KFM06902.1 - 0.1 12.0 4.1 0.14 11.6 2.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin Homeobox PF00046.24 KFM06903.1 - 3.8e-22 77.6 9.7 7.3e-22 76.7 6.7 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFM06903.1 - 0.034 13.8 2.1 0.09 12.4 1.4 1.7 1 0 0 1 1 1 0 Homeobox KN domain Lant_dehyd_N PF04737.8 KFM06903.1 - 0.14 12.2 0.9 0.21 11.6 0.6 1.3 1 0 0 1 1 1 0 Lantibiotic dehydratase, N terminus C2 PF00168.25 KFM06905.1 - 4.1e-12 45.7 0.0 5e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 C2 domain DUF4114 PF13448.1 KFM06905.1 - 0.12 13.1 0.2 0.16 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4114) Tex_N PF09371.5 KFM06906.1 - 4.5e-47 159.8 0.3 8.8e-47 158.9 0.2 1.4 1 0 0 1 1 1 1 Tex-like protein N-terminal domain HHH_3 PF12836.2 KFM06906.1 - 3e-24 84.7 0.0 8.7e-24 83.2 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif S1 PF00575.18 KFM06906.1 - 3.9e-11 42.8 0.4 7.6e-11 41.9 0.3 1.5 1 0 0 1 1 1 1 S1 RNA binding domain HHH_7 PF14635.1 KFM06906.1 - 1.2e-06 28.5 0.0 3.1e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 KFM06906.1 - 1.1e-05 25.0 0.1 2.5e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.1 KFM06906.1 - 0.01 15.8 0.2 0.035 14.1 0.1 1.9 1 0 0 1 1 1 0 Helix-turn-helix DNA-binding domain of SPT6 UPF0081 PF03652.10 KFM06906.1 - 0.026 14.6 0.0 0.078 13.0 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0081) HHH_6 PF14579.1 KFM06906.1 - 0.05 13.6 0.1 0.37 10.8 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF885 PF05960.6 KFM06906.1 - 0.14 11.2 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Methyltransf_16 PF10294.4 KFM06908.1 - 6.2e-17 61.5 0.1 7.5e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.7 KFM06908.1 - 0.00034 21.0 0.0 0.00054 20.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FAE1_CUT1_RppA PF08392.7 KFM06908.1 - 0.0012 18.0 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein Methyltransf_31 PF13847.1 KFM06908.1 - 0.0024 17.4 0.2 0.003 17.1 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFM06908.1 - 0.0032 17.8 0.0 0.0052 17.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFM06908.1 - 0.0035 17.0 0.0 0.035 13.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFM06908.1 - 0.0053 17.2 0.1 0.014 15.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFM06908.1 - 0.018 15.6 0.1 0.032 14.8 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KFM06908.1 - 0.034 13.5 0.4 0.059 12.7 0.2 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Sensor_TM1 PF13755.1 KFM06908.1 - 0.11 11.9 0.0 0.32 10.5 0.0 1.7 2 0 0 2 2 2 0 Sensor N-terminal transmembrane domain Peptidase_S9 PF00326.16 KFM06909.1 - 2.8e-34 118.2 0.0 5.7e-34 117.2 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.10 KFM06909.1 - 2.1e-25 89.1 2.0 4.3e-25 88.1 1.4 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Abhydrolase_6 PF12697.2 KFM06909.1 - 0.0018 18.1 0.0 0.0032 17.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFM06909.1 - 0.04 13.4 0.0 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF4295 PF14128.1 KFM06909.1 - 0.1 12.2 0.6 0.49 10.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4295) Alpha-amylase PF00128.19 KFM06910.1 - 4.1e-70 236.6 2.7 5.8e-70 236.1 1.9 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Nup35_RRM_2 PF14605.1 KFM06910.1 - 0.022 14.5 0.0 0.046 13.4 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Alpha-amylase_C PF02806.13 KFM06910.1 - 0.037 14.1 0.0 0.15 12.1 0.0 2.0 2 0 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain PP2C PF00481.16 KFM06911.1 - 3.4e-83 278.9 0.0 4.2e-83 278.6 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_C PF07830.8 KFM06911.1 - 1.9e-35 120.8 0.1 3.6e-35 119.8 0.1 1.5 1 0 0 1 1 1 1 Protein serine/threonine phosphatase 2C, C-terminal domain PP2C_2 PF13672.1 KFM06911.1 - 2.6e-07 30.2 0.0 5.5e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KFM06911.1 - 0.0016 18.1 0.0 0.8 9.3 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PPR_2 PF13041.1 KFM06912.1 - 3.3e-37 126.2 17.4 5.4e-07 29.4 0.0 14.7 14 2 4 18 18 18 9 PPR repeat family PPR PF01535.15 KFM06912.1 - 2.2e-30 102.4 45.6 0.0016 18.2 0.0 18.5 19 0 0 19 19 19 7 PPR repeat PPR_3 PF13812.1 KFM06912.1 - 2.5e-24 83.4 13.9 0.037 14.3 0.0 14.5 17 0 0 17 17 17 5 Pentatricopeptide repeat domain PPR_1 PF12854.2 KFM06912.1 - 1.7e-19 69.0 14.3 4.6e-05 22.8 0.0 9.6 10 1 1 11 11 11 6 PPR repeat TPR_14 PF13428.1 KFM06912.1 - 4.1e-08 33.1 0.4 6.2 7.7 0.0 8.7 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFM06912.1 - 8.6e-07 29.2 9.9 2.6 8.4 0.4 8.9 7 1 3 10 10 10 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFM06912.1 - 1.2e-05 25.8 0.0 8.4 7.2 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat ATP13 PF12921.2 KFM06912.1 - 0.0069 15.7 0.2 6.1 6.2 0.0 4.8 5 1 0 5 5 5 1 Mitochondrial ATPase expression Ribosomal_L22 PF00237.14 KFM06912.1 - 0.12 12.3 0.4 2.4 8.1 0.1 3.2 3 0 0 3 3 3 0 Ribosomal protein L22p/L17e TPR_7 PF13176.1 KFM06912.1 - 0.32 10.9 8.3 3.4 7.6 0.0 6.1 9 0 0 9 9 9 0 Tetratricopeptide repeat ABC_tran PF00005.22 KFM06913.1 - 1.8e-29 102.8 0.0 2.7e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 KFM06913.1 - 4.4e-20 71.7 10.5 8e-20 70.9 7.3 1.4 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.1 KFM06913.1 - 1.3e-07 31.8 0.7 1.3e-07 31.8 0.5 3.0 3 1 0 3 3 3 1 AAA domain AAA_23 PF13476.1 KFM06913.1 - 1.6e-05 25.3 0.1 2.8e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KFM06913.1 - 3.1e-05 23.4 0.1 6.1e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 KFM06913.1 - 8.6e-05 21.8 0.4 0.0024 17.1 0.3 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KFM06913.1 - 0.00066 18.8 0.0 0.012 14.6 0.1 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.1 KFM06913.1 - 0.0019 18.2 0.0 0.003 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 KFM06913.1 - 0.0025 17.2 0.1 0.0096 15.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KFM06913.1 - 0.0031 16.7 0.0 0.0053 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 NTPase_1 PF03266.10 KFM06913.1 - 0.011 15.4 0.0 1.4 8.5 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA_17 PF13207.1 KFM06913.1 - 0.022 15.5 0.0 0.044 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KFM06913.1 - 0.025 13.4 0.0 0.043 12.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.1 KFM06913.1 - 0.048 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain ArgK PF03308.11 KFM06913.1 - 0.051 12.3 0.0 0.083 11.6 0.0 1.2 1 0 0 1 1 1 0 ArgK protein Arch_ATPase PF01637.13 KFM06913.1 - 0.054 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase UPF0079 PF02367.12 KFM06913.1 - 0.076 12.6 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 KFM06913.1 - 0.086 12.4 0.1 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_10 PF12846.2 KFM06913.1 - 0.11 11.9 0.6 1.2 8.4 0.2 2.1 2 0 0 2 2 2 0 AAA-like domain T2SE PF00437.15 KFM06913.1 - 0.14 11.0 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DLIC PF05783.6 KFM06914.1 - 9.8e-10 37.6 0.0 1.4e-07 30.5 0.0 2.1 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) Gtr1_RagA PF04670.7 KFM06914.1 - 0.0019 17.3 0.0 0.0032 16.6 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 KFM06914.1 - 0.021 14.0 0.0 0.046 12.9 0.0 1.6 1 0 0 1 1 1 0 ADP-ribosylation factor family Miro PF08477.8 KFM06914.1 - 0.038 14.4 0.0 0.17 12.3 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein PH PF00169.24 KFM06915.1 - 6.1e-23 81.0 3.6 7.2e-17 61.5 0.0 3.7 3 0 0 3 3 3 2 PH domain MyTH4 PF00784.12 KFM06915.1 - 6.6e-20 71.1 1.7 1.4e-19 70.0 0.3 2.4 2 0 0 2 2 2 1 MyTH4 domain FERM_M PF00373.13 KFM06915.1 - 3.5e-12 46.5 0.0 3.5e-12 46.5 0.0 2.7 2 1 0 2 2 2 1 FERM central domain PH_11 PF15413.1 KFM06915.1 - 5.2e-08 33.1 2.0 5.2e-08 33.1 1.4 5.1 4 2 0 4 4 4 1 Pleckstrin homology domain DUF2428 PF10350.4 KFM06916.1 - 1e-75 254.1 0.4 2.7e-75 252.7 0.3 1.8 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 KFM06916.1 - 0.00057 19.7 0.0 9.3 6.6 0.0 5.7 5 0 0 5 5 5 1 HEAT repeat XK-related PF09815.4 KFM06917.1 - 1.4e-100 336.5 27.3 1.7e-100 336.2 18.9 1.0 1 0 0 1 1 1 1 XK-related protein P5-ATPase PF12409.3 KFM06917.1 - 6.3 6.6 8.8 0.65 9.8 1.4 2.7 1 1 1 2 2 2 0 P5-type ATPase cation transporter Lactamase_B PF00753.22 KFM06918.1 - 1.2e-24 87.0 1.8 1.8e-24 86.5 1.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KFM06918.1 - 4e-05 23.2 0.3 6.2e-05 22.6 0.2 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain TRAM1 PF08390.6 KFM06919.1 - 6.4e-25 86.4 1.2 1.8e-24 85.0 0.8 1.8 1 0 0 1 1 1 1 TRAM1-like protein TRAM_LAG1_CLN8 PF03798.11 KFM06919.1 - 1e-22 80.6 18.4 1.6e-22 80.0 12.8 1.3 1 0 0 1 1 1 1 TLC domain DUF3112 PF11309.3 KFM06919.1 - 0.0041 16.9 9.6 0.052 13.3 0.9 2.6 1 1 2 3 3 3 2 Protein of unknown function (DUF3112) PAS_11 PF14598.1 KFM06920.1 - 8.2e-39 132.0 6.3 3.2e-35 120.4 0.5 3.0 3 0 0 3 3 3 2 PAS domain DUF1518 PF07469.7 KFM06920.1 - 1.6e-26 92.2 15.6 1.6e-26 92.2 10.8 5.1 3 1 0 3 3 3 1 Domain of unknown function (DUF1518) SRC-1 PF08832.5 KFM06920.1 - 2.4e-25 89.0 5.1 2.4e-25 89.0 3.5 3.6 3 0 0 3 3 3 1 Steroid receptor coactivator Nuc_rec_co-act PF08815.5 KFM06920.1 - 1.1e-22 79.3 0.4 2.9e-22 77.9 0.3 1.8 1 0 0 1 1 1 1 Nuclear receptor coactivator PAS PF00989.19 KFM06920.1 - 2e-07 30.7 1.7 1.1e-06 28.4 0.0 2.8 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.1 KFM06920.1 - 3.3e-07 30.6 0.0 1.5e-06 28.5 0.0 2.1 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.6 KFM06920.1 - 0.00065 19.7 0.0 1.6 8.8 0.0 2.5 2 0 0 2 2 2 2 PAS fold zf-H2C2_2 PF13465.1 KFM06921.1 - 8.7e-26 88.9 56.4 5e-10 39.1 0.4 6.7 7 0 0 7 7 6 6 Zinc-finger double domain zf-C2H2 PF00096.21 KFM06921.1 - 1.3e-19 69.2 58.3 1e-06 28.6 2.5 6.5 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM06921.1 - 1.8e-16 59.1 50.1 3.5e-05 23.8 0.8 6.4 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM06921.1 - 1.1e-10 41.0 33.3 0.002 17.9 0.5 6.9 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM06921.1 - 6.6e-07 29.2 37.1 0.0042 17.1 0.6 6.4 5 1 1 6 6 6 4 Zinc-finger double-stranded RNA-binding SET PF00856.23 KFM06921.1 - 1.9e-06 28.2 0.0 1.8e-05 25.0 0.0 2.4 1 1 0 1 1 1 1 SET domain zf-C2HC_2 PF13913.1 KFM06921.1 - 9.7e-06 25.1 26.8 0.0062 16.1 1.9 6.4 6 0 0 6 6 6 3 zinc-finger of a C2HC-type zf-met PF12874.2 KFM06921.1 - 0.0011 19.1 35.7 0.15 12.2 1.8 6.4 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-BED PF02892.10 KFM06921.1 - 0.0092 15.7 39.9 0.5 10.1 0.5 6.4 2 2 4 6 6 6 3 BED zinc finger zf-C2H2_2 PF12756.2 KFM06921.1 - 0.015 15.4 35.7 0.34 11.0 1.5 5.7 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 KFM06921.1 - 0.078 13.1 36.4 0.58 10.3 4.0 3.9 3 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding PyrI_C PF02748.10 KFM06921.1 - 0.19 11.1 0.1 0.19 11.1 0.1 5.7 3 2 3 6 6 6 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain YhfH PF14149.1 KFM06921.1 - 1.1 9.1 16.3 2.3 8.0 0.5 4.6 3 1 1 4 4 4 0 YhfH-like protein PRP21_like_P PF12230.3 KFM06921.1 - 2.7 7.4 6.9 6.1 6.2 0.7 2.5 2 1 0 3 3 3 0 Pre-mRNA splicing factor PRP21 like protein XPA_N PF01286.13 KFM06921.1 - 4.3 7.1 17.8 3.9 7.2 0.3 5.1 5 0 0 5 5 5 0 XPA protein N-terminal Rad50_zn_hook PF04423.9 KFM06921.1 - 4.7 6.7 12.3 6.3 6.3 0.6 3.6 4 0 0 4 4 4 0 Rad50 zinc hook motif LIM PF00412.17 KFM06921.1 - 6.3 6.9 29.8 1.5 8.9 1.2 4.9 4 1 0 5 5 5 0 LIM domain Sulfatase PF00884.18 KFM06922.1 - 1.3e-52 178.8 1.6 1.5e-52 178.7 0.4 1.6 2 0 0 2 2 2 1 Sulfatase DUF3740 PF12548.3 KFM06922.1 - 1.1e-51 174.9 2.3 1.1e-51 174.9 1.6 2.4 3 0 0 3 3 3 1 Sulfatase protein Phosphodiest PF01663.17 KFM06922.1 - 1.5e-08 34.3 0.9 1.5e-08 34.3 0.7 1.7 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 KFM06922.1 - 0.074 12.4 0.0 0.21 10.9 0.0 1.7 1 1 0 1 1 1 0 Metalloenzyme superfamily UCH PF00443.24 KFM06924.1 - 0.03 13.4 0.1 0.064 12.3 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase FCH PF00611.18 KFM06925.1 - 1.1e-16 60.7 0.1 1.1e-16 60.7 0.1 2.3 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain TEX12 PF15219.1 KFM06925.1 - 0.53 10.2 2.8 5.5 7.0 0.7 2.4 1 1 1 2 2 2 0 Testis-expressed 12 Spore_II_R PF09551.5 KFM06925.1 - 0.56 10.2 3.6 1.2 9.1 0.1 2.3 2 0 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) CENP-H PF05837.7 KFM06925.1 - 0.95 9.6 8.4 0.33 11.1 2.9 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) COG2 PF06148.6 KFM06925.1 - 1.1 9.1 6.1 0.21 11.4 0.9 2.2 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 ATP-synt_ab PF00006.20 KFM06926.1 - 1.5e-72 243.5 0.0 2.3e-72 242.9 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KFM06926.1 - 1.3e-27 96.4 0.5 2.7e-27 95.4 0.3 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KFM06926.1 - 1.9e-18 66.3 1.9 5.2e-18 65.0 1.3 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF4142 PF13628.1 KFM06926.1 - 0.0018 18.3 2.5 0.0037 17.2 1.7 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4142) HAS-barrel PF09378.5 KFM06926.1 - 0.015 15.1 1.9 0.1 12.5 1.3 2.2 1 1 0 1 1 1 0 HAS barrel domain TPR_MLP1_2 PF07926.7 KFM06927.1 - 0.0012 18.5 22.8 0.0026 17.5 3.2 3.0 2 1 1 3 3 3 2 TPR/MLP1/MLP2-like protein Vps52 PF04129.7 KFM06927.1 - 0.022 13.2 5.5 0.31 9.5 0.3 2.2 1 1 1 2 2 2 0 Vps52 / Sac2 family Atg14 PF10186.4 KFM06927.1 - 0.069 12.0 8.1 0.12 11.2 5.6 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ADIP PF11559.3 KFM06927.1 - 0.2 11.5 18.7 2.9 7.7 5.4 3.0 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding THP2 PF09432.5 KFM06927.1 - 0.28 11.0 8.0 0.096 12.5 0.6 2.8 2 1 1 3 3 3 0 Tho complex subunit THP2 ATG16 PF08614.6 KFM06927.1 - 0.57 9.9 18.9 4 7.2 9.8 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Mnd1 PF03962.10 KFM06927.1 - 0.85 9.2 12.6 2.3 7.8 6.9 2.4 2 1 0 2 2 2 0 Mnd1 family Fib_alpha PF08702.5 KFM06927.1 - 1.8 8.7 13.6 0.58 10.2 4.8 2.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF3496 PF12001.3 KFM06927.1 - 2.4 8.4 9.9 0.81 9.9 4.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3496) Lipoprotein_20 PF13942.1 KFM06927.1 - 9.9 5.6 12.0 26 4.3 2.2 2.4 1 1 1 2 2 2 0 YfhG lipoprotein RNF111_N PF15303.1 KFM06928.1 - 1.9e-81 273.5 32.5 3.7e-81 272.5 22.5 1.4 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase Arkadia N-terminus zf-RING_2 PF13639.1 KFM06929.1 - 8.9e-16 57.4 6.1 8.9e-16 57.4 4.2 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFM06929.1 - 3.8e-09 36.0 3.8 3.8e-09 36.0 2.6 1.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM06929.1 - 2.7e-08 33.6 5.6 2.7e-08 33.6 3.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFM06929.1 - 7.4e-08 32.4 6.3 2.1e-07 30.9 4.4 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KFM06929.1 - 1.5e-07 30.9 4.8 1.5e-07 30.9 3.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM06929.1 - 1.9e-07 30.7 3.4 1.9e-07 30.7 2.3 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 KFM06929.1 - 0.0025 17.6 4.3 0.0061 16.3 3.0 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KFM06929.1 - 0.021 14.5 0.9 0.021 14.5 0.6 1.9 1 1 0 1 1 1 0 RING-type zinc-finger zf-Nse PF11789.3 KFM06929.1 - 0.039 13.4 1.5 0.094 12.2 1.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit OrfB_Zn_ribbon PF07282.6 KFM06929.1 - 0.041 13.5 0.9 1.4 8.6 0.1 2.3 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zf-RING_4 PF14570.1 KFM06929.1 - 0.042 13.4 3.4 0.072 12.6 2.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 KFM06929.1 - 0.069 13.1 5.1 0.19 11.8 3.5 1.7 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 KFM06929.1 - 0.28 11.1 5.5 1.1 9.2 3.8 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 KFM06929.1 - 0.57 10.1 4.1 1.3 8.9 2.8 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.9 KFM06929.1 - 0.67 9.4 3.7 0.39 10.2 0.6 2.0 2 0 0 2 2 2 0 P-11 zinc finger Prok-RING_1 PF14446.1 KFM06929.1 - 3.4 7.4 5.6 2.5 7.8 0.7 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 PINIT PF14324.1 KFM06930.1 - 1.4e-41 141.9 0.1 2.5e-41 141.1 0.0 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 KFM06930.1 - 5.4e-21 73.8 5.3 1.2e-20 72.7 3.7 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 KFM06930.1 - 0.00025 20.4 1.8 0.00084 18.8 1.3 1.9 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.22 KFM06930.1 - 0.0015 18.0 0.0 0.0037 16.7 0.0 1.8 1 0 0 1 1 1 1 SAP domain PHD PF00628.24 KFM06930.1 - 0.15 11.7 2.2 0.31 10.7 1.5 1.5 1 0 0 1 1 1 0 PHD-finger AAA PF00004.24 KFM06931.1 - 5.7e-38 130.0 0.0 1e-37 129.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFM06931.1 - 4.5e-05 23.5 0.1 0.00013 22.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KFM06931.1 - 5.5e-05 22.3 0.0 9.2e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KFM06931.1 - 9e-05 22.5 0.0 0.0022 18.0 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KFM06931.1 - 0.00016 22.4 0.0 0.00034 21.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFM06931.1 - 0.00042 20.0 0.0 0.00095 18.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 KFM06931.1 - 0.00047 18.9 0.0 0.00074 18.3 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 KFM06931.1 - 0.00048 19.8 0.0 0.0013 18.4 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_24 PF13479.1 KFM06931.1 - 0.0015 18.1 0.0 0.012 15.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KFM06931.1 - 0.002 17.5 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 KFM06931.1 - 0.0024 17.7 0.0 0.0044 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KFM06931.1 - 0.0045 16.4 0.7 0.1 12.0 0.3 2.3 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.17 KFM06931.1 - 0.005 16.9 0.0 0.016 15.3 0.0 1.9 2 0 0 2 2 1 1 RNA helicase Mg_chelatase PF01078.16 KFM06931.1 - 0.0053 15.9 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 KFM06931.1 - 0.013 15.4 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KFM06931.1 - 0.032 13.4 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein DUF815 PF05673.8 KFM06931.1 - 0.036 13.0 0.0 0.054 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 KFM06931.1 - 0.048 13.9 0.1 0.12 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 KFM06931.1 - 0.051 12.4 0.1 0.21 10.4 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.1 KFM06931.1 - 0.067 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 KFM06931.1 - 0.075 12.5 0.0 1.6 8.1 0.0 2.6 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_2 PF07724.9 KFM06931.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Hydrolase_like PF13242.1 KFM06932.1 - 1.4e-18 66.3 0.0 1.9e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 KFM06932.1 - 1.2e-07 32.1 0.0 1.8e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFM06932.1 - 0.0014 19.1 0.1 0.0016 18.8 0.1 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 KFM06933.1 - 7.3e-17 61.1 0.0 1.2e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFM06933.1 - 1.1e-14 53.8 0.1 4.4e-14 51.9 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 KFM06933.1 - 1.7e-08 34.9 0.0 5.3e-07 30.0 0.0 2.3 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFM06933.1 - 0.00011 22.7 0.5 0.0046 17.3 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4032 PF13224.1 KFM06933.1 - 0.063 12.9 0.0 0.095 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4032) Yos1 PF08571.5 KFM06934.1 - 3e-15 56.0 0.1 3.2e-15 55.9 0.1 1.0 1 0 0 1 1 1 1 Yos1-like BTB PF00651.26 KFM06935.1 - 1.8e-33 114.8 1.5 1.2e-32 112.2 0.4 2.2 2 0 0 2 2 2 1 BTB/POZ domain zf-H2C2_2 PF13465.1 KFM06935.1 - 7.2e-22 76.5 31.6 8.3e-08 32.1 0.7 5.2 5 0 0 5 5 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM06935.1 - 1.3e-10 40.8 24.7 0.001 19.2 2.5 5.3 5 0 0 5 5 4 4 C2H2-type zinc finger zf-C2H2 PF00096.21 KFM06935.1 - 1.6e-07 31.2 40.3 0.0005 20.2 5.0 6.0 6 1 0 6 6 4 4 Zinc finger, C2H2 type zf-RING_3 PF14369.1 KFM06935.1 - 0.017 15.1 0.9 1.3 9.0 0.0 3.5 3 0 0 3 3 3 0 zinc-finger zf-C2H2_jaz PF12171.3 KFM06935.1 - 0.036 14.2 1.5 0.036 14.2 1.1 5.5 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM06935.1 - 0.038 14.1 19.1 1.3 9.2 0.1 4.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type RXT2_N PF08595.6 KFM06935.1 - 0.1 12.3 6.7 0.21 11.3 4.7 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal CDC45 PF02724.9 KFM06935.1 - 0.11 10.4 5.7 0.15 10.0 4.0 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.7 KFM06935.1 - 0.12 11.5 15.7 0.17 10.9 10.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT zf-Di19 PF05605.7 KFM06935.1 - 0.12 12.4 14.5 3.7 7.7 4.8 3.4 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding BTV_NS2 PF04514.7 KFM06935.1 - 0.15 10.8 6.3 0.26 10.1 4.3 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 HSP90 PF00183.13 KFM06935.1 - 0.17 10.2 8.3 0.27 9.6 5.8 1.2 1 0 0 1 1 1 0 Hsp90 protein Daxx PF03344.10 KFM06935.1 - 0.23 9.8 18.8 0.35 9.3 13.0 1.1 1 0 0 1 1 1 0 Daxx Family FAM176 PF14851.1 KFM06935.1 - 0.25 11.0 7.5 0.49 10.0 5.2 1.5 1 0 0 1 1 1 0 FAM176 family GAGA PF09237.6 KFM06935.1 - 0.35 10.5 6.6 0.39 10.3 0.1 3.3 1 1 3 4 4 4 0 GAGA factor Sigma70_ner PF04546.8 KFM06935.1 - 0.39 10.3 12.1 0.65 9.5 8.4 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region BSP_II PF05432.6 KFM06935.1 - 0.4 9.9 14.7 0.64 9.2 10.2 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Mpp10 PF04006.7 KFM06935.1 - 0.44 8.8 19.2 0.66 8.2 13.3 1.1 1 0 0 1 1 1 0 Mpp10 protein VID27 PF08553.5 KFM06935.1 - 0.62 8.2 6.7 0.84 7.7 4.6 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein TRAP_alpha PF03896.11 KFM06935.1 - 0.79 8.6 8.1 1.4 7.8 5.6 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Dicty_REP PF05086.7 KFM06935.1 - 1.9 6.1 9.0 2.5 5.7 6.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Myc_N PF01056.13 KFM06935.1 - 2.1 7.4 11.2 4.4 6.3 7.8 1.5 1 0 0 1 1 1 0 Myc amino-terminal region zf-C2H2_2 PF12756.2 KFM06935.1 - 2.4 8.3 17.5 14 5.8 0.6 4.6 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) Sporozoite_P67 PF05642.6 KFM06935.1 - 2.8 5.7 5.8 3.7 5.2 4.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Zn_Tnp_IS1595 PF12760.2 KFM06935.1 - 4.9 7.0 10.8 4.8 7.0 2.1 2.8 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF2722 PF10846.3 KFM06935.1 - 5.9 5.7 7.3 8.9 5.2 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Nop14 PF04147.7 KFM06935.1 - 6.2 4.5 19.8 8.9 4.0 13.7 1.1 1 0 0 1 1 1 0 Nop14-like family MH2 PF03166.9 KFM06937.1 - 1.5e-62 210.6 0.1 1.7e-62 210.4 0.1 1.0 1 0 0 1 1 1 1 MH2 domain KH_1 PF00013.24 KFM06938.1 - 6.7e-06 25.6 2.0 2e-05 24.1 0.5 2.3 2 1 0 2 2 2 1 KH domain KH_3 PF13014.1 KFM06938.1 - 7.4e-05 22.3 0.1 0.00017 21.1 0.0 1.6 1 0 0 1 1 1 1 KH domain PDEase_I PF00233.14 KFM06939.1 - 1e-65 221.8 0.0 2e-65 220.8 0.0 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.21 KFM06939.1 - 6.6e-36 123.7 0.0 1.7e-25 89.9 0.0 2.4 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.1 KFM06939.1 - 2.7e-21 75.9 0.0 2.7e-13 50.1 0.0 2.7 3 0 0 3 3 3 2 GAF domain GAF_2 PF13185.1 KFM06939.1 - 6.8e-14 52.5 0.0 5.9e-08 33.3 0.0 2.4 2 0 0 2 2 2 2 GAF domain HD PF01966.17 KFM06939.1 - 0.075 13.0 0.2 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 HD domain T-box PF00907.17 KFM06940.1 - 1.6e-25 89.6 0.1 2.2e-25 89.2 0.1 1.2 1 0 0 1 1 1 1 T-box Got1 PF04178.7 KFM06941.1 - 1.6e-31 108.8 16.3 2e-31 108.5 11.3 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Na_Ca_ex PF01699.19 KFM06941.1 - 0.63 9.6 9.6 1.6 8.3 6.6 1.8 1 1 0 1 1 1 0 Sodium/calcium exchanger protein DUF4293 PF14126.1 KFM06941.1 - 1.5 8.7 7.9 0.86 9.5 3.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) PGG PF13962.1 KFM06941.1 - 3.8 7.1 9.5 1.3 8.6 1.4 2.4 1 1 1 2 2 2 0 Domain of unknown function DUF4064 PF13273.1 KFM06941.1 - 6 7.0 9.0 51 4.0 6.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) MtN3_slv PF03083.11 KFM06941.1 - 7.6 6.4 10.8 0.92 9.4 4.1 2.0 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange PTPS_related PF10131.4 KFM06941.1 - 9.4 4.2 12.1 9.8 4.1 8.4 1.0 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein MPC PF03650.8 KFM06942.1 - 2.1e-34 118.0 0.2 2.3e-34 117.8 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Pkinase PF00069.20 KFM06943.1 - 3.1e-74 249.4 0.0 3.9e-74 249.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM06943.1 - 1.1e-34 119.6 0.0 1.4e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM06943.1 - 4.4e-06 25.8 0.0 3.5e-05 22.9 0.0 2.3 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 KFM06943.1 - 4.6e-06 25.8 0.0 9.9e-06 24.7 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KFM06943.1 - 0.002 17.5 0.0 0.0036 16.6 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 KFM06943.1 - 0.025 14.3 0.0 0.19 11.4 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 KFM06943.1 - 0.034 13.5 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family tRNA-synt_1f PF01921.13 KFM06943.1 - 0.14 10.8 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (K) GpcrRhopsn4 PF10192.4 KFM06944.1 - 1e-80 270.6 6.4 1.3e-80 270.3 4.4 1.1 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.8 KFM06944.1 - 1.9e-08 33.6 3.0 3.9e-08 32.6 2.0 1.6 1 1 0 1 1 1 1 Lung seven transmembrane receptor PLAC8 PF04749.12 KFM06944.1 - 0.0056 17.2 7.7 0.0074 16.8 1.9 3.1 2 1 0 2 2 2 1 PLAC8 family MraZ PF02381.13 KFM06944.1 - 0.14 11.9 0.4 0.8 9.5 0.1 2.4 2 0 0 2 2 2 0 MraZ protein DUF2231 PF09990.4 KFM06944.1 - 3.3 8.1 6.4 2.8 8.3 0.2 3.2 2 1 0 3 3 3 0 Predicted membrane protein (DUF2231) Epimerase PF01370.16 KFM06945.1 - 3.2e-58 196.9 0.1 4.2e-58 196.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KFM06945.1 - 3e-26 91.9 0.0 3.6e-26 91.7 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KFM06945.1 - 3.5e-23 81.9 0.0 1.5e-22 79.9 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KFM06945.1 - 5.6e-21 74.4 0.0 7.8e-21 73.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KFM06945.1 - 1.1e-18 67.0 0.0 1.6e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KFM06945.1 - 2.8e-07 30.7 0.0 3.8e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Tyrosinase PF00264.15 KFM06946.1 - 1.6e-31 110.2 0.0 2.1e-31 109.8 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase RCR PF12273.3 KFM06946.1 - 0.1 13.1 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Glypican PF01153.14 KFM06947.1 - 1.3e-201 671.0 0.0 1.5e-201 670.8 0.0 1.0 1 0 0 1 1 1 1 Glypican TGF_beta_GS PF08515.7 KFM06947.1 - 0.71 9.2 3.8 1.7 8.0 2.6 1.7 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif Gag_p30 PF02093.11 KFM06949.1 - 3.4e-25 88.5 0.1 4.1e-25 88.2 0.1 1.0 1 0 0 1 1 1 1 Gag P30 core shell protein CENP-O PF09496.5 KFM06949.1 - 0.031 14.5 0.1 0.079 13.1 0.0 1.7 2 1 0 2 2 2 0 Cenp-O kinetochore centromere component Gag_p24 PF00607.15 KFM06949.1 - 0.037 13.5 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) Fork_head PF00250.13 KFM06949.1 - 0.049 13.6 0.0 0.087 12.8 0.0 1.4 1 0 0 1 1 1 0 Fork head domain RVT_1 PF00078.22 KFM06950.1 - 4.2e-22 78.5 0.0 5.6e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Gag_p30 PF02093.11 KFM06951.1 - 1.6e-22 79.7 0.1 2e-22 79.4 0.1 1.0 1 0 0 1 1 1 1 Gag P30 core shell protein Gag_p24 PF00607.15 KFM06951.1 - 4.3e-05 23.1 0.3 9.3e-05 22.0 0.2 1.5 1 1 0 1 1 1 1 gag gene protein p24 (core nucleocapsid protein) FlgM PF04316.8 KFM06951.1 - 0.13 12.2 0.1 2.2 8.2 0.0 2.3 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM GED PF02212.13 KFM06951.1 - 0.13 12.1 0.1 0.48 10.3 0.0 1.8 2 0 0 2 2 2 0 Dynamin GTPase effector domain BH4 PF02180.12 KFM06952.1 - 0.42 10.1 9.6 28 4.3 0.1 4.2 2 1 3 5 5 5 0 Bcl-2 homology region 4 RVT_1 PF00078.22 KFM06953.1 - 0.14 11.4 0.0 0.3 10.3 0.0 1.5 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) LRR_8 PF13855.1 KFM06955.1 - 6.9e-46 153.8 33.3 6.2e-15 54.7 4.6 5.9 2 2 3 5 5 5 4 Leucine rich repeat LRR_4 PF12799.2 KFM06955.1 - 1e-24 85.6 38.5 3.8e-07 29.5 0.3 7.3 2 2 6 9 9 9 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM06955.1 - 5.2e-18 62.3 38.4 0.062 13.3 0.0 12.1 12 0 0 12 12 12 6 Leucine Rich Repeat LRR_5 PF13306.1 KFM06955.1 - 6.8e-18 64.6 0.0 1.4e-08 34.5 0.0 2.3 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_7 PF13504.1 KFM06955.1 - 1.6e-06 27.3 41.7 0.55 10.6 0.4 11.1 11 0 0 11 11 11 4 Leucine rich repeat LRR_9 PF14580.1 KFM06955.1 - 0.011 15.2 9.4 0.68 9.4 0.8 3.7 2 2 3 5 5 5 0 Leucine-rich repeat Neur_chan_memb PF02932.11 KFM06955.1 - 0.013 15.3 0.9 0.022 14.6 0.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region LRR_6 PF13516.1 KFM06955.1 - 0.014 15.3 29.1 35 4.9 0.1 10.1 9 0 0 9 9 9 0 Leucine Rich repeat TMEM154 PF15102.1 KFM06955.1 - 0.023 14.3 0.1 0.054 13.2 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family LRRNT PF01462.13 KFM06955.1 - 0.091 12.2 7.6 0.035 13.5 1.7 2.8 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain LRR_8 PF13855.1 KFM06959.1 - 3.1e-53 177.3 57.7 1.6e-11 43.8 0.3 6.8 2 2 6 8 8 8 8 Leucine rich repeat LRR_4 PF12799.2 KFM06959.1 - 3.2e-21 74.4 36.6 0.00072 19.1 0.0 8.9 3 2 8 11 11 11 11 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM06959.1 - 1.6e-16 57.7 29.1 0.38 10.9 0.0 12.8 13 0 0 13 13 13 6 Leucine Rich Repeat LRR_7 PF13504.1 KFM06959.1 - 0.026 14.6 34.6 3.1 8.4 0.1 11.2 12 0 0 12 12 12 0 Leucine rich repeat LRR_9 PF14580.1 KFM06959.1 - 0.36 10.3 9.8 0.61 9.6 1.3 3.2 2 2 2 4 4 4 0 Leucine-rich repeat LRRNT PF01462.13 KFM06959.1 - 0.91 9.0 17.0 0.042 13.3 2.0 3.1 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain Yae1_N PF09811.4 KFM06961.1 - 5.1e-13 48.3 38.7 6.7e+02 -0.1 26.8 4.0 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Sprouty PF05210.8 KFM06963.1 - 5.1e-37 126.2 34.6 8e-37 125.5 24.0 1.3 1 0 0 1 1 1 1 Sprouty protein (Spry) DUF3049 PF11250.3 KFM06964.1 - 0.19 11.4 0.7 1.5 8.6 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3049) DUF2370 PF10176.4 KFM06965.1 - 2.2e-46 158.1 12.3 4.2e-35 121.1 3.5 3.0 1 1 1 2 2 2 2 Protein of unknown function (DUF2370) DUF3446 PF11928.3 KFM06965.1 - 0.69 10.1 11.1 1.3 9.2 7.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) DUF202 PF02656.10 KFM06965.1 - 0.7 10.1 3.9 3.3 7.9 2.7 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF202) 6PF2K PF01591.13 KFM06967.1 - 2.1e-102 340.9 1.4 2.8e-102 340.5 0.5 1.5 2 0 0 2 2 2 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KFM06967.1 - 2.8e-36 125.0 0.0 5e-36 124.1 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KFM06967.1 - 3.2e-09 36.8 0.0 9e-09 35.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 KFM06967.1 - 8.8e-05 21.8 0.2 0.00017 20.8 0.1 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 KFM06967.1 - 0.00031 21.5 0.5 0.0023 18.7 0.1 2.6 2 1 0 2 2 2 1 AAA domain Prefoldin PF02996.12 KFM06967.1 - 0.00059 19.4 1.2 0.00084 18.9 0.0 1.9 2 0 0 2 2 2 1 Prefoldin subunit Zeta_toxin PF06414.7 KFM06967.1 - 0.017 14.1 0.0 0.047 12.7 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin His_Phos_2 PF00328.17 KFM06967.1 - 0.032 13.5 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) AAA_18 PF13238.1 KFM06967.1 - 0.078 13.2 0.3 0.58 10.4 0.0 2.4 2 1 1 3 3 3 0 AAA domain HSF_DNA-bind PF00447.12 KFM06968.1 - 2.2e-20 72.7 0.0 2.5e-20 72.5 0.0 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding Glyco_hydro_56 PF01630.13 KFM06969.1 - 4.3e-129 429.9 0.1 5.2e-129 429.7 0.0 1.0 1 0 0 1 1 1 1 Hyaluronidase EGF_2 PF07974.8 KFM06969.1 - 0.02 15.0 13.3 0.68 10.1 1.2 2.5 2 0 0 2 2 2 0 EGF-like domain Glyco_hydro_56 PF01630.13 KFM06970.1 - 2.6e-138 460.2 0.4 3.2e-138 460.0 0.3 1.0 1 0 0 1 1 1 1 Hyaluronidase TUSC2 PF15000.1 KFM06971.1 - 3.9e-31 107.3 0.0 4.2e-31 107.2 0.0 1.0 1 0 0 1 1 1 1 Tumour suppressor candidate 2 DUF346 PF03984.8 KFM06971.1 - 0.066 12.6 0.0 0.096 12.1 0.0 1.2 1 0 0 1 1 1 0 Repeat of unknown function (DUF346) RA PF00788.18 KFM06972.1 - 8.8e-17 61.3 1.8 1.1e-16 61.1 0.1 1.9 3 0 0 3 3 3 1 Ras association (RalGDS/AF-6) domain Ras_bdg_2 PF14847.1 KFM06972.1 - 0.036 13.9 0.0 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 Ras-binding domain of Byr2 zf-MYND PF01753.13 KFM06973.1 - 6.4e-10 38.7 19.8 6.4e-10 38.7 13.7 2.1 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.11 KFM06973.1 - 0.82 9.3 8.1 1.5 8.5 5.6 1.5 1 0 0 1 1 1 0 HIT zinc finger NPR2 PF06218.6 KFM06974.1 - 2e-112 376.0 8.4 7.3e-95 318.1 3.4 2.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 NPR3 PF03666.8 KFM06974.1 - 0.042 12.3 0.0 0.24 9.8 0.0 2.0 2 1 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Cytochrom_B561 PF03188.11 KFM06975.1 - 3.3e-30 104.7 10.7 4.7e-30 104.2 7.4 1.2 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4131 PF13567.1 KFM06975.1 - 0.25 10.7 10.7 0.11 11.8 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Ni_hydr_CYTB PF01292.15 KFM06975.1 - 8.4 5.7 10.4 31 3.8 7.2 2.0 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 DUF1751 PF08551.5 KFM06976.1 - 7.1e-19 67.9 1.7 7.1e-19 67.9 1.2 2.1 2 2 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) VWA PF00092.23 KFM06977.1 - 5.3e-10 39.3 0.0 6.1e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 KFM06977.1 - 7.7e-08 32.6 0.0 9.9e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain Cache_1 PF02743.13 KFM06977.1 - 0.00028 20.3 0.0 0.00066 19.1 0.0 1.7 1 0 0 1 1 1 1 Cache domain VWA_3 PF13768.1 KFM06977.1 - 0.00049 19.8 0.0 0.0007 19.3 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain Epimerase_Csub PF13950.1 KFM06978.1 - 0.084 12.8 0.0 0.092 12.6 0.0 1.1 1 0 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit TM1586_NiRdase PF14512.1 KFM06978.1 - 0.12 11.5 0.1 0.12 11.5 0.1 1.0 1 0 0 1 1 1 0 Putative TM nitroreductase Herpes_gE PF02480.11 KFM06979.1 - 0.011 14.0 0.0 0.012 13.8 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF1049 PF06305.6 KFM06979.1 - 0.013 14.9 0.1 0.022 14.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF1469 PF07332.6 KFM06979.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Methyltransf_26 PF13659.1 KFM06980.1 - 1.3e-19 70.3 0.0 2.7e-19 69.3 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 KFM06980.1 - 8.6e-16 57.7 0.0 1.7e-15 56.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 KFM06980.1 - 5.7e-14 52.6 0.0 1e-13 51.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFM06980.1 - 1.9e-11 43.7 0.0 3e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KFM06980.1 - 3.8e-08 32.7 0.0 6.4e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.10 KFM06980.1 - 1.3e-07 31.1 0.0 2.7e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.1 KFM06980.1 - 4.1e-06 27.0 0.0 8.1e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 KFM06980.1 - 4.3e-06 26.4 0.0 7.8e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.7 KFM06980.1 - 1.5e-05 25.4 0.0 3.1e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KFM06980.1 - 4.3e-05 22.6 0.0 0.00013 21.1 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_12 PF08242.7 KFM06980.1 - 0.00018 21.8 0.0 0.00037 20.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 KFM06980.1 - 0.00042 21.1 0.1 0.00093 20.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFM06980.1 - 0.00096 18.9 0.0 0.004 16.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KFM06980.1 - 0.0037 16.7 0.0 0.0058 16.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase TehB PF03848.9 KFM06980.1 - 0.0071 15.5 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB RrnaAD PF00398.15 KFM06980.1 - 0.0074 15.3 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase N6_N4_Mtase PF01555.13 KFM06980.1 - 0.0091 15.5 0.0 0.11 12.0 0.0 2.1 2 0 0 2 2 2 1 DNA methylase Methyltransf_3 PF01596.12 KFM06980.1 - 0.011 14.7 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_15 PF09445.5 KFM06980.1 - 0.018 14.6 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.1 KFM06980.1 - 0.033 13.8 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 KFM06980.1 - 0.036 13.6 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_5 PF01795.14 KFM06980.1 - 0.036 13.3 0.0 0.071 12.3 0.0 1.4 1 0 0 1 1 1 0 MraW methylase family PCMT PF01135.14 KFM06980.1 - 0.043 13.3 0.0 0.074 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF1436 PF07262.6 KFM06980.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1436) DUF938 PF06080.7 KFM06980.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) SH2 PF00017.19 KFM06981.1 - 6.7e-14 51.4 0.0 1.1e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 SH2 domain SOCS_box PF07525.11 KFM06981.1 - 5.5e-13 48.5 1.4 1.3e-12 47.3 0.9 1.7 1 0 0 1 1 1 1 SOCS box Pkinase PF00069.20 KFM06982.1 - 2e-63 213.9 0.0 3.5e-63 213.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM06982.1 - 2.1e-29 102.4 0.0 3.1e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFM06982.1 - 6.1e-07 28.7 0.1 1.2e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KFM06982.1 - 0.00043 19.3 0.0 0.00098 18.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.15 KFM06982.1 - 0.015 14.8 0.0 0.079 12.5 0.0 2.0 1 1 0 1 1 1 0 Choline/ethanolamine kinase DUF2132 PF09905.4 KFM06982.1 - 0.059 13.3 0.0 0.48 10.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2132) APH PF01636.18 KFM06982.1 - 0.11 12.2 0.0 0.7 9.5 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family EGF_CA PF07645.10 KFM06983.1 - 0 1046.5 741.9 6.9e-11 41.9 5.2 48.7 48 2 2 50 50 50 44 Calcium-binding EGF domain cEGF PF12662.2 KFM06983.1 - 4.1e-194 627.3 443.8 1.1e-08 34.5 3.9 51.1 52 0 0 52 52 52 44 Complement Clr-like EGF-like EGF PF00008.22 KFM06983.1 - 4.1e-126 410.1 683.4 8.3e-06 25.6 7.1 49.5 49 0 0 49 49 49 45 EGF-like domain TB PF00683.12 KFM06983.1 - 3.7e-113 368.8 150.0 2e-15 56.0 5.7 11.7 10 0 0 10 10 10 9 TB domain FXa_inhibition PF14670.1 KFM06983.1 - 3.7e-104 340.5 741.3 2.9e-08 33.6 5.6 49.3 47 3 3 50 50 50 42 Coagulation Factor Xa inhibitory site EGF_3 PF12947.2 KFM06983.1 - 1.1e-42 143.6 647.8 1.1e-09 38.0 8.7 50.2 48 3 2 50 50 50 40 EGF domain FAP PF07174.6 KFM06983.1 - 1.7 7.8 0.1 1.2e+02 1.7 0.0 3.1 2 2 0 2 2 2 0 Fibronectin-attachment protein (FAP) Cortexin PF11057.3 KFM06984.1 - 7.4e-34 115.1 0.2 8e-34 115.0 0.2 1.0 1 0 0 1 1 1 1 Cortexin of kidney NTPase_I-T PF01931.13 KFM06985.1 - 5.3e-08 32.7 0.0 8.3e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF84 Laminin_EGF PF00053.19 KFM06986.1 - 1.5e-47 159.2 329.4 0.0014 18.4 15.0 18.2 5 3 12 17 17 17 16 Laminin EGF-like (Domains III and V) hEGF PF12661.2 KFM06986.1 - 4.5e-17 60.8 312.3 0.0014 18.5 3.6 32.9 34 0 0 34 34 34 21 Human growth factor-like EGF EGF_2 PF07974.8 KFM06986.1 - 6.8e-09 35.7 387.7 0.0016 18.5 12.9 25.3 20 10 7 27 27 27 14 EGF-like domain Baculo_11_kDa PF06143.6 KFM06986.1 - 0.033 13.5 0.8 0.06 12.7 0.5 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF912 PF06024.7 KFM06986.1 - 0.088 12.8 0.1 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Syndecan PF01034.15 KFM06986.1 - 0.11 12.2 0.3 0.21 11.2 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain DUF2207 PF09972.4 KFM06986.1 - 0.4 9.2 0.1 0.58 8.6 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Rifin_STEVOR PF02009.11 KFM06986.1 - 0.49 10.0 0.4 0.81 9.2 0.3 1.3 1 0 0 1 1 1 0 Rifin/stevor family DUF836 PF05768.9 KFM06987.1 - 2.7e-16 59.6 0.1 3.2e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.19 KFM06987.1 - 0.00033 20.5 0.2 0.00047 20.0 0.1 1.4 1 1 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 KFM06987.1 - 0.00094 19.3 0.1 0.0011 19.1 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KFM06987.1 - 0.0014 18.5 0.0 0.0025 17.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like RINGv PF12906.2 KFM06988.1 - 5.9e-14 51.8 10.7 8.4e-14 51.3 7.4 1.2 1 0 0 1 1 1 1 RING-variant domain Baculo_IE-1 PF05290.6 KFM06988.1 - 0.0013 18.4 1.0 0.0016 18.2 0.7 1.1 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4_2 PF13923.1 KFM06988.1 - 2.1 8.4 6.0 6.6 6.8 4.2 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM06988.1 - 2.5 7.8 9.7 1.4 8.5 4.3 2.3 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KFM06988.1 - 2.8 7.6 5.5 8.1 6.1 2.9 2.3 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain PHD PF00628.24 KFM06988.1 - 2.8 7.7 8.5 5 6.8 5.9 1.5 1 0 0 1 1 1 0 PHD-finger Cytochrome_C7 PF14522.1 KFM06988.1 - 3.1 7.4 6.8 73 3.0 4.8 2.2 1 1 0 1 1 1 0 Cytochrome c7 zf-C3HC4_3 PF13920.1 KFM06988.1 - 3.3 7.4 7.4 9.3 6.0 5.2 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM06988.1 - 8.2 6.3 14.1 1.7 8.5 7.0 1.9 2 0 0 2 2 2 0 Ring finger domain V-set PF07686.12 KFM06989.1 - 1.6e-06 28.0 0.0 1.6e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.1 KFM06989.1 - 0.06 13.8 0.0 0.066 13.7 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain Keratin PF02422.11 KFM06990.1 - 1.1e-38 131.0 23.6 2e-38 130.2 16.4 1.4 1 1 0 1 1 1 1 Keratin FERM_M PF00373.13 KFM06992.1 - 9.7e-22 77.4 0.1 3e-21 75.8 0.0 1.9 1 0 0 1 1 1 1 FERM central domain PDZ PF00595.19 KFM06992.1 - 1e-10 41.6 0.0 2.3e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) WW PF00397.21 KFM06992.1 - 5.6e-05 22.9 0.0 0.00013 21.7 0.0 1.7 1 0 0 1 1 1 1 WW domain PDZ_2 PF13180.1 KFM06992.1 - 9e-05 22.2 0.0 0.00024 20.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain FERM_N PF09379.5 KFM06992.1 - 0.012 15.6 0.2 0.03 14.3 0.1 1.7 1 0 0 1 1 1 0 FERM N-terminal domain Pribosyl_synth PF14572.1 KFM06993.1 - 1.4e-44 152.0 2.1 4.7e-37 127.5 0.6 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 KFM06993.1 - 2.5e-33 114.2 0.7 1.9e-32 111.4 0.0 2.3 2 1 1 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 KFM06993.1 - 2.9e-10 39.9 1.0 1.1e-09 38.1 0.5 1.9 1 1 1 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KFM06993.1 - 0.00013 21.2 0.1 0.00021 20.5 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase LRR_8 PF13855.1 KFM06994.1 - 1e-69 230.1 92.2 1.1e-09 37.8 1.9 14.6 9 4 6 15 15 15 15 Leucine rich repeat LRR_4 PF12799.2 KFM06994.1 - 1e-44 149.5 98.8 1.8e-06 27.3 0.3 15.7 9 3 7 16 16 16 13 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM06994.1 - 3e-27 90.4 93.4 0.14 12.2 0.5 23.7 24 2 1 25 25 25 12 Leucine Rich Repeat TIR PF01582.15 KFM06994.1 - 5.6e-20 71.2 0.3 9.4e-20 70.4 0.2 1.4 1 0 0 1 1 1 1 TIR domain LRR_7 PF13504.1 KFM06994.1 - 6.9e-11 40.5 68.7 3.3 8.3 0.2 21.3 23 0 0 23 23 23 5 Leucine rich repeat LRR_5 PF13306.1 KFM06994.1 - 2.8e-10 39.9 30.8 4.5e-06 26.3 0.4 6.9 5 1 1 7 7 7 3 Leucine rich repeats (6 copies) LRR_9 PF14580.1 KFM06994.1 - 2.6e-06 27.0 23.3 0.059 12.9 2.2 7.2 4 2 2 7 7 7 2 Leucine-rich repeat TIR_2 PF13676.1 KFM06994.1 - 8.1e-05 22.7 0.0 0.00016 21.7 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_6 PF13516.1 KFM06994.1 - 0.025 14.6 87.9 5 7.4 0.1 20.2 19 4 3 22 22 21 0 Leucine Rich repeat Cytokin_check_N PF10407.4 KFM06994.1 - 0.15 11.6 3.6 18 5.0 0.0 4.3 4 0 0 4 4 4 0 Cdc14 phosphatase binding protein N-terminus LRRNT PF01462.13 KFM06994.1 - 2.4 7.7 8.2 0.59 9.6 0.0 3.8 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain MAM PF00629.18 KFM06995.1 - 4.3e-26 91.6 0.0 8.5e-26 90.6 0.0 1.5 1 0 0 1 1 1 1 MAM domain EGF_CA PF07645.10 KFM06995.1 - 1.4e-23 82.6 39.5 5.2e-11 42.3 7.1 6.3 4 2 1 5 5 5 3 Calcium-binding EGF domain cEGF PF12662.2 KFM06995.1 - 3e-14 52.3 39.5 0.00019 20.9 0.5 6.0 5 0 0 5 5 5 5 Complement Clr-like EGF-like EGF_3 PF12947.2 KFM06995.1 - 9.9e-12 44.6 22.0 2.4e-10 40.1 8.3 6.3 5 1 0 5 5 5 3 EGF domain FXa_inhibition PF14670.1 KFM06995.1 - 1.7e-10 40.8 74.4 3.6e-06 27.0 5.7 5.6 4 1 1 5 5 5 4 Coagulation Factor Xa inhibitory site EGF PF00008.22 KFM06995.1 - 1.4e-07 31.3 74.3 0.0019 18.1 5.2 5.8 5 0 0 5 5 5 4 EGF-like domain TFIIS_M PF07500.9 KFM06996.1 - 8e-30 103.2 2.8 8e-30 103.2 2.0 1.7 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain Med26 PF08711.6 KFM06996.1 - 2.3e-09 36.6 0.1 5.5e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain TFIIS_C PF01096.13 KFM06996.1 - 0.0063 16.1 0.2 0.0063 16.1 0.2 2.6 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Pam17 PF08566.5 KFM06996.1 - 0.0069 16.1 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Ubiq_cyt_C_chap PF03981.7 KFM06996.1 - 0.015 15.1 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone Ras PF00071.17 KFM06997.1 - 3.2e-57 192.4 0.0 3.7e-57 192.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM06997.1 - 7.4e-18 65.1 0.0 1.1e-17 64.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM06997.1 - 9.9e-12 44.4 0.0 1.2e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFM06997.1 - 6.9e-06 25.3 0.0 9.3e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFM06997.1 - 7.8e-06 25.8 0.0 1.2e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KFM06997.1 - 0.0032 16.6 0.1 0.0082 15.3 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KFM06997.1 - 0.0038 16.6 0.0 0.0062 15.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 KFM06997.1 - 0.0054 16.2 0.0 1.4 8.3 0.0 2.1 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 KFM06997.1 - 0.0083 15.6 0.2 0.057 12.9 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 KFM06997.1 - 0.038 13.9 0.0 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 KFM06997.1 - 0.086 12.9 0.0 0.2 11.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 KFM06997.1 - 0.11 11.7 0.0 0.26 10.5 0.0 1.6 2 1 1 3 3 3 0 Ferrous iron transport protein B Arch_ATPase PF01637.13 KFM06997.1 - 0.13 11.9 0.3 0.52 9.9 0.0 1.9 2 1 0 2 2 2 0 Archaeal ATPase DUF3168 PF11367.3 KFM06997.1 - 0.17 12.0 0.5 5 7.2 0.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3168) Sedlin_N PF04628.8 KFM06998.1 - 4.2e-46 156.0 0.4 4.7e-46 155.9 0.3 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 KFM06998.1 - 2.1e-09 37.1 0.1 2.7e-09 36.8 0.1 1.2 1 0 0 1 1 1 1 Sybindin-like family Pex14_N PF04695.8 KFM06998.1 - 0.026 14.5 0.1 0.24 11.4 0.0 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Myelin_PLP PF01275.14 KFM06999.1 - 4.7e-125 415.7 21.0 5.4e-125 415.5 14.5 1.0 1 0 0 1 1 1 1 Myelin proteolipid protein (PLP or lipophilin) PspB PF06667.7 KFM06999.1 - 0.0085 16.0 0.1 0.022 14.7 0.0 1.7 1 0 0 1 1 1 1 Phage shock protein B DUF1049 PF06305.6 KFM06999.1 - 0.017 14.5 2.5 0.067 12.6 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) FA_desaturase PF00487.19 KFM06999.1 - 2.7 7.3 10.1 0.029 13.8 0.8 2.2 2 1 0 2 2 2 0 Fatty acid desaturase GEMIN8 PF15348.1 KFM07000.1 - 6.1e-78 261.6 15.5 7e-78 261.4 10.8 1.0 1 0 0 1 1 1 1 Gemini of Cajal bodies-associated protein 8 Neuregulin PF02158.10 KFM07000.1 - 0.059 12.1 0.6 0.077 11.7 0.4 1.2 1 0 0 1 1 1 0 Neuregulin family Neur_chan_LBD PF02931.18 KFM07001.1 - 4.7e-55 186.0 0.0 6.1e-55 185.7 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFM07001.1 - 9.5e-46 156.6 4.4 1.5e-38 133.0 0.9 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region RDD PF06271.7 KFM07001.1 - 0.31 10.9 3.7 0.13 12.1 0.4 1.8 2 0 0 2 2 2 0 RDD family CRAL_TRIO PF00650.15 KFM07003.1 - 4.3e-28 97.8 0.2 7.3e-28 97.0 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Motile_Sperm PF00635.21 KFM07003.1 - 2.5e-21 75.3 0.0 5.9e-21 74.1 0.0 1.7 1 0 0 1 1 1 1 MSP (Major sperm protein) domain CRAL_TRIO_2 PF13716.1 KFM07003.1 - 7.5e-06 25.9 1.4 9.7e-06 25.5 0.0 1.8 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain SDF PF00375.13 KFM07004.1 - 9.9e-134 445.9 28.2 1.2e-133 445.7 19.5 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family adh_short PF00106.20 KFM07007.1 - 2e-18 66.8 0.0 2.5e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFM07007.1 - 5e-09 36.2 0.0 2e-08 34.3 0.0 1.7 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase HMG_box PF00505.14 KFM07007.1 - 0.1 12.9 0.6 0.21 11.9 0.4 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box Ldl_recept_a PF00057.13 KFM07008.1 - 0 1084.5 690.7 2.1e-12 46.7 5.0 38.3 38 0 0 38 38 38 36 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.12 KFM07008.1 - 2e-209 677.7 105.3 5.1e-12 45.9 0.0 38.1 39 1 0 39 39 39 31 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.1 KFM07008.1 - 1.3e-65 217.1 332.8 8.1e-10 38.6 3.9 23.9 22 1 0 22 22 22 16 Coagulation Factor Xa inhibitory site cEGF PF12662.2 KFM07008.1 - 8.2e-24 82.9 152.9 6.9e-09 35.1 1.9 18.2 18 0 0 18 18 18 10 Complement Clr-like EGF-like SGL PF08450.7 KFM07008.1 - 8.4e-15 54.8 27.7 0.037 13.3 0.6 14.7 9 7 3 14 14 14 6 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 KFM07008.1 - 5.3e-05 23.1 0.0 34 4.5 0.0 9.1 11 1 1 12 12 12 0 Arylesterase DUF2621 PF11084.3 KFM07008.1 - 2.7 7.6 0.1 5.8 6.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) Collagen PF01391.13 KFM07009.1 - 1.3e-66 220.0 288.3 4.6e-10 38.8 15.6 12.0 2 2 9 11 11 11 11 Collagen triple helix repeat (20 copies) VWA PF00092.23 KFM07009.1 - 1.9e-65 219.9 0.9 2.3e-39 134.9 0.3 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.1 KFM07009.1 - 7.2e-23 81.5 0.1 6.2e-13 49.2 0.1 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_3 PF13768.1 KFM07009.1 - 2.3e-07 30.6 0.0 0.0033 17.1 0.0 3.0 3 0 0 3 3 3 2 von Willebrand factor type A domain DUF1448 PF07289.6 KFM07010.1 - 1.9e-145 484.0 0.1 2.2e-145 483.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1448) bPH_3 PF14470.1 KFM07010.1 - 1.7e-05 25.0 0.0 0.0023 18.1 0.0 2.3 2 0 0 2 2 2 1 Bacterial PH domain GRAM PF02893.15 KFM07010.1 - 4.5e-05 22.8 0.0 0.0076 15.7 0.0 2.6 3 0 0 3 3 3 2 GRAM domain Vps36_ESCRT-II PF11605.3 KFM07010.1 - 5.7e-05 22.8 0.0 0.23 11.2 0.0 2.4 2 0 0 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 Voldacs PF03517.8 KFM07010.1 - 0.0032 17.2 0.2 0.29 10.9 0.0 2.7 3 0 0 3 3 3 1 Regulator of volume decrease after cellular swelling Kelch_1 PF01344.20 KFM07011.1 - 2.1e-46 155.1 0.0 3.2e-11 42.5 0.0 5.6 6 0 0 6 6 6 5 Kelch motif BACK PF07707.10 KFM07011.1 - 1.1e-30 105.4 0.7 2.7e-30 104.2 0.2 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_6 PF13964.1 KFM07011.1 - 1.8e-30 103.7 0.1 3.9e-09 36.2 0.0 5.6 1 1 4 5 5 5 4 Kelch motif BTB PF00651.26 KFM07011.1 - 9.3e-29 99.6 1.2 1.5e-28 99.0 0.4 1.7 2 0 0 2 2 2 1 BTB/POZ domain Kelch_4 PF13418.1 KFM07011.1 - 1e-24 86.0 0.2 1.3e-07 31.2 0.0 5.2 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.1 KFM07011.1 - 1.1e-21 76.3 0.0 1.8e-05 24.7 0.0 5.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.10 KFM07011.1 - 3.3e-17 61.4 0.1 0.093 12.5 0.0 5.5 4 1 1 5 5 5 5 Kelch motif Kelch_5 PF13854.1 KFM07011.1 - 6.9e-14 51.4 0.0 0.12 12.3 0.0 5.5 5 0 0 5 5 5 4 Kelch motif DUF3342 PF11822.3 KFM07011.1 - 0.0025 17.0 0.6 0.005 16.0 0.2 1.6 1 1 0 2 2 2 1 Domain of unknown function (DUF3342) FAST_2 PF08368.7 KFM07012.1 - 9.5e-29 99.6 0.3 1.1e-27 96.1 0.0 2.9 2 0 0 2 2 2 1 FAST kinase-like protein, subdomain 2 FAST_1 PF06743.10 KFM07012.1 - 1.5e-18 66.2 13.8 6e-15 54.7 1.5 4.2 3 0 0 3 3 3 3 FAST kinase-like protein, subdomain 1 RAP PF08373.5 KFM07012.1 - 6e-16 57.9 1.5 3.7e-15 55.4 0.1 2.9 3 0 0 3 3 3 1 RAP domain Pro_isomerase PF00160.16 KFM07013.1 - 1.6e-47 161.6 0.4 1.6e-47 161.6 0.3 2.3 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SR-25 PF10500.4 KFM07013.1 - 3.8e-07 29.8 40.6 3.8e-07 29.8 28.1 5.7 2 1 3 5 5 5 1 Nuclear RNA-splicing-associated protein Trichoplein PF13868.1 KFM07014.1 - 1.1e-07 30.5 124.5 1.1e-07 30.5 86.3 2.5 1 1 1 2 2 2 1 Tumour suppressor, Mitostatin Put_Phosphatase PF06888.7 KFM07015.1 - 1.3e-92 309.2 0.0 1.4e-92 309.0 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.2 KFM07015.1 - 3.3e-09 37.1 0.0 4.8e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KFM07015.1 - 0.012 15.8 0.3 0.063 13.4 0.2 2.0 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase NIF PF03031.13 KFM07015.1 - 0.018 14.6 0.3 2 8.0 0.1 3.2 1 1 1 2 2 2 0 NLI interacting factor-like phosphatase DHquinase_II PF01220.14 KFM07015.1 - 0.16 11.2 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Dehydroquinase class II Kelch_1 PF01344.20 KFM07016.1 - 1.4e-50 168.5 31.2 3.2e-12 45.7 0.3 6.9 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.1 KFM07016.1 - 2.1e-38 128.9 12.5 9.4e-09 35.0 0.0 6.4 2 2 4 6 6 6 6 Kelch motif BTB PF00651.26 KFM07016.1 - 4.7e-31 107.0 1.2 8.1e-31 106.2 0.8 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.1 KFM07016.1 - 6e-31 105.9 3.2 6.1e-05 22.7 0.1 6.4 5 1 1 6 6 6 6 Galactose oxidase, central domain BACK PF07707.10 KFM07016.1 - 3.4e-25 87.8 5.7 3.7e-25 87.7 1.8 2.4 3 0 0 3 3 3 1 BTB And C-terminal Kelch Kelch_2 PF07646.10 KFM07016.1 - 1.5e-22 78.4 15.8 0.00062 19.4 0.0 7.1 6 2 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 KFM07016.1 - 4.6e-21 74.4 2.8 1.4e-05 25.1 0.1 6.4 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 KFM07016.1 - 2e-08 34.0 23.5 0.0026 17.6 0.3 6.8 7 0 0 7 7 7 4 Kelch motif DUF3342 PF11822.3 KFM07016.1 - 0.0001 21.5 0.3 0.00018 20.7 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) RRM_3 PF08777.6 KFM07017.1 - 4.4e-32 110.0 1.3 4.4e-32 110.0 0.9 3.4 3 1 0 3 3 3 1 RNA binding motif La PF05383.12 KFM07017.1 - 1.5e-23 82.3 0.1 2.6e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 KFM07017.1 - 9.7e-15 53.9 0.2 1.4e-09 37.4 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM07017.1 - 9.3e-13 47.9 0.0 6e-08 32.5 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM07017.1 - 0.0087 15.8 1.1 3.5 7.5 0.0 3.7 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IncA PF04156.9 KFM07017.1 - 4.3 6.8 13.5 6.7 6.2 0.0 2.5 2 1 0 2 2 2 0 IncA protein Peptidase_S49_N PF08496.5 KFM07017.1 - 6.8 6.4 16.1 0.073 12.8 2.9 2.7 3 0 0 3 3 3 0 Peptidase family S49 N-terminal MTS PF05175.9 KFM07018.1 - 1.1e-14 54.1 0.1 1.7e-14 53.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 KFM07018.1 - 1.1e-11 44.4 0.2 1.8e-11 43.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 KFM07018.1 - 2.8e-11 43.4 0.0 3.9e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFM07018.1 - 3.5e-10 40.4 0.0 5.2e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFM07018.1 - 5.8e-10 38.9 0.5 8.1e-10 38.4 0.3 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 KFM07018.1 - 7.4e-10 38.6 0.1 1e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.10 KFM07018.1 - 1.9e-08 33.9 0.0 2.4e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.5 KFM07018.1 - 5.7e-06 25.9 0.2 8.7e-06 25.3 0.1 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.1 KFM07018.1 - 3.9e-05 23.9 1.7 6.1e-05 23.3 0.9 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFM07018.1 - 0.00045 20.6 0.1 0.0011 19.3 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFM07018.1 - 0.00096 19.5 0.1 0.0022 18.4 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KFM07018.1 - 0.0018 17.3 0.0 0.003 16.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase FmrO PF07091.6 KFM07018.1 - 0.002 17.1 0.4 0.0032 16.4 0.3 1.3 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) DNA_methylase PF00145.12 KFM07018.1 - 0.004 16.3 0.0 0.0079 15.3 0.0 1.5 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase N6_Mtase PF02384.11 KFM07018.1 - 0.0097 15.0 0.3 0.023 13.7 0.2 1.8 1 1 0 1 1 1 1 N-6 DNA Methylase Methyltransf_9 PF08003.6 KFM07018.1 - 0.012 14.3 0.2 0.025 13.2 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) DUF43 PF01861.11 KFM07018.1 - 0.013 14.4 0.0 0.023 13.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF43 Methyltransf_16 PF10294.4 KFM07018.1 - 0.019 14.3 0.2 0.039 13.3 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase DUF2431 PF10354.4 KFM07018.1 - 0.023 14.6 0.1 0.037 13.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) CRAL_TRIO PF00650.15 KFM07019.1 - 0.0091 15.4 0.4 0.031 13.7 0.3 2.0 1 0 0 1 1 1 1 CRAL/TRIO domain zf-C3HC4 PF00097.20 KFM07019.1 - 0.012 15.2 0.5 0.012 15.2 0.4 3.6 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Myosin_head PF00063.16 KFM07020.1 - 1.4e-204 681.1 0.7 1.6e-204 680.8 0.5 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Pkinase PF00069.20 KFM07020.1 - 1.9e-61 207.5 0.0 2.9e-61 206.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM07020.1 - 6.5e-41 140.1 0.0 1e-40 139.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFM07020.1 - 2.2e-06 27.5 0.0 0.075 12.7 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family IQ PF00612.22 KFM07020.1 - 1.5e-05 24.2 5.6 0.0013 18.1 0.0 3.0 3 0 0 3 3 3 2 IQ calmodulin-binding motif Kinase-like PF14531.1 KFM07020.1 - 2e-05 23.6 0.0 5e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Kinase-like AAA_22 PF13401.1 KFM07020.1 - 0.039 14.0 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KFM07020.1 - 0.067 12.2 0.0 0.16 11.0 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.22 KFM07020.1 - 0.15 12.3 0.0 0.48 10.7 0.0 1.8 1 0 0 1 1 1 0 ABC transporter zf-C2H2 PF00096.21 KFM07021.1 - 6e-20 70.3 13.4 1.1e-07 31.7 0.5 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM07021.1 - 3.5e-18 64.9 7.4 2e-10 40.4 1.0 3.5 4 0 0 4 4 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM07021.1 - 7.7e-15 54.0 11.8 4.5e-06 26.6 0.7 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM07021.1 - 5.5e-07 29.5 3.6 0.1 12.7 0.1 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 KFM07021.1 - 1.3e-05 24.7 9.2 0.078 12.7 1.3 3.2 1 1 2 3 3 3 3 BED zinc finger zf-C2H2_6 PF13912.1 KFM07021.1 - 4.4e-05 23.2 4.6 0.088 12.7 0.1 3.2 3 1 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.7 KFM07021.1 - 0.00026 21.0 2.3 0.00026 21.0 1.6 2.1 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 KFM07021.1 - 0.0004 19.9 3.4 0.4 10.4 0.5 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-met PF12874.2 KFM07021.1 - 0.00074 19.6 4.6 1.9 8.7 0.1 3.6 3 1 0 3 3 3 2 Zinc-finger of C2H2 type RRN7 PF11781.3 KFM07021.1 - 0.0079 15.6 1.5 0.11 11.9 0.1 2.2 2 0 0 2 2 2 1 RNA polymerase I-specific transcription initiation factor Rrn7 Ogr_Delta PF04606.7 KFM07021.1 - 0.015 14.9 0.5 5 6.8 0.0 2.3 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zf-ribbon_3 PF13248.1 KFM07021.1 - 0.016 14.4 0.6 0.24 10.6 0.0 2.6 3 0 0 3 3 3 0 zinc-ribbon domain Mcm10 PF09332.6 KFM07021.1 - 0.03 13.6 3.9 0.023 14.0 1.9 1.4 1 1 1 2 2 2 0 Mcm10 replication factor zf-C2H2_2 PF12756.2 KFM07021.1 - 0.045 13.8 3.2 2.1 8.5 2.2 2.5 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Zn_Tnp_IS1595 PF12760.2 KFM07021.1 - 0.046 13.5 6.7 0.051 13.3 0.3 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain XPA_N PF01286.13 KFM07021.1 - 0.058 13.0 0.8 0.21 11.3 0.1 2.1 2 0 0 2 2 2 0 XPA protein N-terminal zf-TRAF PF02176.13 KFM07021.1 - 0.08 13.3 2.7 7.8 6.9 0.3 2.2 1 1 0 2 2 2 0 TRAF-type zinc finger DUF1610 PF07754.6 KFM07021.1 - 0.082 13.0 0.8 0.082 13.0 0.6 2.3 4 0 0 4 4 2 0 Domain of unknown function (DUF1610) Zn_Tnp_IS1 PF03811.8 KFM07021.1 - 0.082 12.4 0.7 0.18 11.3 0.5 1.6 1 0 0 1 1 1 0 InsA N-terminal domain zf-RING_3 PF14369.1 KFM07021.1 - 0.092 12.7 0.1 0.092 12.7 0.1 1.8 2 1 0 2 2 2 0 zinc-finger zf-LYAR PF08790.6 KFM07021.1 - 0.093 12.4 2.3 6.1 6.6 0.1 3.2 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger FYDLN_acid PF09538.5 KFM07021.1 - 0.11 13.1 0.8 1.3 9.6 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) Nudix_N_2 PF14803.1 KFM07021.1 - 0.24 11.1 1.1 0.8 9.4 0.8 2.1 1 1 0 1 1 1 0 Nudix N-terminal ADK_lid PF05191.9 KFM07021.1 - 0.91 9.2 4.1 1.6 8.4 0.3 2.7 3 0 0 3 3 3 0 Adenylate kinase, active site lid Zn-ribbon_8 PF09723.5 KFM07021.1 - 1.9 8.4 5.7 1.7 8.6 0.3 2.4 2 1 1 3 3 2 0 Zinc ribbon domain ROS_MUCR PF05443.6 KFM07021.1 - 2.3 8.0 5.9 8 6.2 0.1 2.7 1 1 2 3 3 3 0 ROS/MUCR transcriptional regulator protein zinc_ribbon_2 PF13240.1 KFM07021.1 - 2.5 7.7 5.5 0.89 9.1 0.3 2.6 3 0 0 3 3 3 0 zinc-ribbon domain A2L_zn_ribbon PF08792.5 KFM07021.1 - 3.1 7.3 5.1 6.3 6.3 0.1 2.6 3 0 0 3 3 2 0 A2L zinc ribbon domain Pyridoxal_deC PF00282.14 KFM07022.1 - 3.7e-147 489.6 0.0 4.3e-147 489.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 KFM07022.1 - 7.3e-06 25.3 0.0 1.3e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KFM07022.1 - 3.6e-05 22.6 0.0 0.00033 19.4 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V SLA_LP_auto_ag PF05889.8 KFM07022.1 - 0.0076 14.7 0.0 0.012 14.0 0.0 1.3 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) OKR_DC_1 PF01276.15 KFM07022.1 - 0.038 12.5 0.0 0.059 11.9 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Aminotran_1_2 PF00155.16 KFM07022.1 - 0.065 12.1 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KFM07022.1 - 0.11 11.5 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family GRASP55_65 PF04495.9 KFM07023.1 - 5.7e-78 259.6 0.0 7.4e-63 210.6 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 KFM07023.1 - 3.1e-05 23.7 0.1 0.052 13.4 0.0 2.8 3 0 0 3 3 3 2 PDZ domain Pkinase PF00069.20 KFM07024.1 - 4e-58 196.5 0.2 1e-57 195.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM07024.1 - 1.1e-34 119.7 0.0 2.4e-34 118.5 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Methyltransf_23 PF13489.1 KFM07025.1 - 1.5e-12 47.5 0.0 3.2e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFM07025.1 - 1.2e-11 44.9 0.2 3.8e-11 43.3 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFM07025.1 - 2.7e-10 40.6 0.0 6e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFM07025.1 - 9.9e-09 35.4 0.1 3.2e-08 33.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFM07025.1 - 1.1e-07 31.5 0.0 3e-07 30.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFM07025.1 - 1.9e-05 25.1 0.1 4.4e-05 24.0 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFM07025.1 - 0.00041 20.3 0.0 0.00074 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 KFM07025.1 - 0.0062 17.3 0.0 0.017 15.9 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain CheR PF01739.13 KFM07025.1 - 0.0095 15.2 0.0 0.28 10.4 0.0 2.4 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain NodS PF05401.6 KFM07025.1 - 0.027 13.8 0.0 0.05 12.9 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) MTS PF05175.9 KFM07025.1 - 0.087 12.1 0.0 0.22 10.8 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Cytochrom_B561 PF03188.11 KFM07027.1 - 4.3e-38 130.2 8.9 4.3e-38 130.2 6.2 1.6 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 Cytochrom_B_N PF00033.14 KFM07027.1 - 0.001 18.4 13.3 0.095 12.0 9.6 2.7 1 1 1 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Ni_hydr_CYTB PF01292.15 KFM07027.1 - 0.042 13.2 13.3 0.61 9.4 3.6 2.4 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 Ferric_reduct PF01794.14 KFM07027.1 - 0.11 12.6 9.3 0.029 14.4 2.6 2.2 1 1 1 2 2 2 0 Ferric reductase like transmembrane component Trp_oprn_chp PF09534.5 KFM07027.1 - 0.18 11.3 0.0 0.18 11.3 0.0 2.2 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) NfeD PF01957.13 KFM07027.1 - 0.63 10.1 5.4 3 7.9 0.0 2.2 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding DUF1230 PF06799.6 KFM07027.1 - 1.1 9.0 3.4 2.6 7.9 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1230) COPI_assoc PF08507.5 KFM07027.1 - 4.4 6.9 8.3 32 4.2 5.9 2.3 1 1 0 1 1 1 0 COPI associated protein DUF4293 PF14126.1 KFM07027.1 - 4.8 7.0 7.8 12 5.8 1.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) Mito_carr PF00153.22 KFM07028.1 - 8.1e-71 233.8 0.4 2.1e-26 91.4 0.1 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 KFM07028.1 - 1.9e-12 47.1 1.0 0.0005 20.1 0.1 4.4 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.27 KFM07028.1 - 3e-12 44.8 4.1 0.017 14.3 0.1 5.4 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.1 KFM07028.1 - 1.3e-10 40.1 1.6 0.021 14.6 0.0 6.0 6 0 0 6 6 6 2 EF-hand domain EF-hand_8 PF13833.1 KFM07028.1 - 1.1e-05 24.9 0.1 0.027 14.0 0.0 4.2 5 0 0 5 5 5 1 EF-hand domain pair EF-hand_5 PF13202.1 KFM07028.1 - 0.00022 20.4 0.7 5.2 6.5 0.0 4.0 3 0 0 3 3 3 2 EF hand EF-hand_like PF09279.6 KFM07028.1 - 0.052 13.5 0.8 5.9 6.9 0.2 2.6 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like Hat1_N PF10394.4 KFM07029.1 - 3e-44 150.9 0.7 1.1e-43 149.1 0.6 1.8 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_7 PF13508.1 KFM07029.1 - 7.4e-05 22.8 0.0 0.00044 20.3 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFM07029.1 - 0.0013 18.8 0.0 0.0028 17.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Peptidase_M24 PF00557.19 KFM07030.1 - 3e-50 170.6 0.0 4.5e-50 170.0 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Homeobox PF00046.24 KFM07031.1 - 4.3e-05 23.0 0.7 7.7e-05 22.2 0.5 1.4 1 0 0 1 1 1 1 Homeobox domain Integrin_alpha2 PF08441.7 KFM07032.1 - 8.1e-115 384.2 6.4 1.1e-114 383.7 4.4 1.2 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.18 KFM07032.1 - 1.7e-17 62.5 22.1 1.7e-07 30.6 4.3 3.8 3 0 0 3 3 3 3 FG-GAP repeat VCBS PF13517.1 KFM07032.1 - 7.1e-12 45.5 13.0 9.3e-09 35.5 3.4 3.0 1 1 1 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella BCDHK_Adom3 PF10436.4 KFM07033.1 - 1.8e-53 180.4 0.0 2.7e-53 179.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KFM07033.1 - 6.4e-22 77.3 0.0 1.7e-21 76.0 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KFM07033.1 - 0.0011 18.6 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PDZ PF00595.19 KFM07034.1 - 1.4e-13 50.8 2.8 2.2e-13 50.1 1.1 2.1 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) SAM_2 PF07647.12 KFM07034.1 - 1.5e-09 37.5 0.4 3.7e-09 36.2 0.3 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFM07034.1 - 1.1e-07 31.9 1.0 1.1e-07 31.9 0.7 2.3 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 KFM07034.1 - 0.00021 20.9 1.6 0.00046 19.8 1.1 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain DUF2407_C PF13373.1 KFM07034.1 - 0.042 13.7 3.1 0.15 11.9 2.1 2.0 1 0 0 1 1 1 0 DUF2407 C-terminal domain PsbU PF06514.6 KFM07034.1 - 0.15 11.8 1.6 0.37 10.6 0.0 2.5 2 1 1 3 3 3 0 Photosystem II 12 kDa extrinsic protein (PsbU) SlyX PF04102.7 KFM07034.1 - 1.6 9.1 12.9 0.11 12.8 2.1 3.8 3 0 0 3 3 3 0 SlyX Pkinase_Tyr PF07714.12 KFM07035.1 - 4.7e-64 215.9 0.0 7.9e-64 215.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM07035.1 - 1.9e-59 200.9 0.0 3.8e-59 199.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain SAM_2 PF07647.12 KFM07035.1 - 2.1e-09 37.1 0.2 6.4e-09 35.5 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFM07035.1 - 2.5e-09 37.1 4.0 1.2e-08 35.0 0.2 3.3 4 0 0 4 4 4 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 KFM07035.1 - 0.0053 16.4 0.1 0.018 14.8 0.1 1.9 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Sugarporin_N PF11471.3 KFM07035.1 - 4.1 7.1 7.6 9.1 6.0 5.3 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension zf-H2C2_2 PF13465.1 KFM07036.1 - 8.3e-14 51.0 9.0 2.3e-08 33.9 2.0 4.7 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFM07036.1 - 9.6e-14 50.8 26.4 1.6e-05 24.9 1.5 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM07036.1 - 8.3e-11 41.4 18.2 0.00028 20.9 0.9 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.7 KFM07036.1 - 0.0038 17.3 1.6 0.0038 17.3 1.1 2.6 2 1 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 KFM07036.1 - 0.023 14.8 7.1 1 9.5 0.9 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFM07036.1 - 1.5 8.8 16.7 1.8 8.5 0.8 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger YchF-GTPase_C PF06071.8 KFM07037.1 - 4.6e-41 138.4 1.0 4.6e-41 138.4 0.7 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 KFM07037.1 - 7.5e-11 42.0 0.0 3e-10 40.0 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 KFM07037.1 - 0.0017 18.1 0.0 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 KFM07037.1 - 0.14 11.4 0.0 0.3 10.3 0.0 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B Peptidase_C69 PF03577.10 KFM07039.1 - 5.5e-10 38.6 0.1 7.9e-10 38.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C69 AAT PF03417.11 KFM07039.1 - 0.015 14.7 0.1 0.22 10.9 0.0 2.5 3 0 0 3 3 3 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Mem_trans PF03547.13 KFM07040.1 - 4.3e-21 74.6 21.7 1.6e-13 49.7 4.9 3.6 2 2 1 3 3 3 2 Membrane transport protein DEP PF00610.16 KFM07040.1 - 2.6e-12 46.2 0.0 6.1e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PT PF04886.7 KFM07040.1 - 2.9 7.3 7.0 4.8 6.5 4.8 1.3 1 0 0 1 1 1 0 PT repeat Neur_chan_LBD PF02931.18 KFM07041.1 - 5e-71 238.2 1.6 6.7e-71 237.8 1.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFM07041.1 - 6.2e-64 216.1 10.7 1.5e-49 169.0 5.9 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DUF2207 PF09972.4 KFM07041.1 - 3.3 6.1 6.5 3.9 5.9 3.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF1129 PF06570.6 KFM07041.1 - 6 6.1 9.2 14 4.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) RhoGAP PF00620.22 KFM07042.1 - 3.8e-50 169.4 0.0 6.7e-50 168.6 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.17 KFM07042.1 - 2e-15 56.2 7.9 3.5e-15 55.4 5.4 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH2 PF00017.19 KFM07042.1 - 1.3e-14 53.7 0.1 2.7e-14 52.7 0.1 1.6 1 0 0 1 1 1 1 SH2 domain FYVE_2 PF02318.11 KFM07042.1 - 0.013 15.3 1.9 0.026 14.4 1.3 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger PHD_2 PF13831.1 KFM07042.1 - 0.057 12.7 1.5 0.12 11.6 1.1 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 KFM07042.1 - 0.078 12.9 5.1 0.16 11.9 3.5 1.5 1 0 0 1 1 1 0 RING-like domain PHD PF00628.24 KFM07042.1 - 4.2 7.1 7.5 8.5 6.1 5.2 1.5 1 0 0 1 1 1 0 PHD-finger ATP-synt_C PF00137.16 KFM07043.1 - 1.6e-17 63.1 13.7 2e-17 62.8 9.5 1.2 1 0 0 1 1 1 1 ATP synthase subunit C WxL PF13731.1 KFM07043.1 - 0.078 12.7 0.1 0.094 12.5 0.0 1.0 1 0 0 1 1 1 0 WxL domain surface cell wall-binding DUF2296 PF10058.4 KFM07044.1 - 5.5e-22 77.2 0.3 8.3e-22 76.6 0.2 1.3 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) Homeobox PF00046.24 KFM07046.1 - 4.8e-19 67.7 6.0 5.7e-19 67.4 4.2 1.1 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFM07046.1 - 0.0012 18.4 2.7 0.0019 17.8 1.9 1.5 1 1 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 KFM07046.1 - 0.031 13.3 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez HTH_23 PF13384.1 KFM07046.1 - 0.034 13.7 0.1 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain Homeobox PF00046.24 KFM07047.1 - 1.8e-20 72.2 10.7 2e-20 72.1 7.4 1.0 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 KFM07047.1 - 0.00017 20.5 0.2 0.00018 20.4 0.1 1.2 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.6 KFM07047.1 - 0.026 14.2 3.2 0.052 13.2 2.2 1.7 1 1 0 1 1 1 0 Homeobox KN domain Daxx PF03344.10 KFM07047.1 - 0.44 8.9 5.3 0.5 8.7 3.7 1.0 1 0 0 1 1 1 0 Daxx Family DUF3528 PF12045.3 KFM07048.1 - 1.5e-68 229.4 1.3 2.4e-68 228.7 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3528) Homeobox PF00046.24 KFM07048.1 - 9.5e-21 73.1 8.1 1.7e-20 72.3 5.6 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFM07048.1 - 0.22 11.2 1.9 0.22 11.2 0.2 1.8 2 0 0 2 2 2 0 Homeobox KN domain Homeobox PF00046.24 KFM07049.1 - 2.6e-21 74.9 9.5 3.3e-21 74.6 4.1 2.4 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 KFM07049.1 - 0.036 13.7 0.2 0.036 13.7 0.2 2.6 3 0 0 3 3 3 0 Homeobox KN domain Hox9_act PF04617.8 KFM07050.1 - 2.7e-52 177.5 2.3 4e-52 177.0 1.6 1.2 1 0 0 1 1 1 1 Hox9 activation region Homeobox PF00046.24 KFM07050.1 - 2.6e-21 75.0 6.2 3.8e-21 74.4 4.3 1.3 1 0 0 1 1 1 1 Homeobox domain HTH_23 PF13384.1 KFM07050.1 - 0.043 13.4 0.0 0.099 12.3 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Homeobox PF00046.24 KFM07051.1 - 7.4e-22 76.7 5.9 7.4e-22 76.7 4.1 1.7 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 KFM07051.1 - 0.01 15.5 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 0 Homeobox KN domain MRP-63 PF14978.1 KFM07051.1 - 0.035 14.5 0.8 0.088 13.2 0.2 1.9 2 0 0 2 2 2 0 Mitochondrial ribosome protein 63 Homeobox PF00046.24 KFM07052.1 - 1.9e-22 78.5 8.8 3.6e-22 77.7 6.1 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFM07052.1 - 0.024 14.3 1.1 0.051 13.2 0.7 1.5 1 0 0 1 1 1 0 Homeobox KN domain DUF4074 PF13293.1 KFM07053.1 - 2.7e-33 113.9 7.9 2.7e-33 113.9 5.5 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4074) Homeobox PF00046.24 KFM07053.1 - 1.1e-21 76.1 4.8 1.6e-21 75.6 3.3 1.3 1 0 0 1 1 1 1 Homeobox domain GST_C_3 PF14497.1 KFM07054.1 - 2.1e-12 47.3 0.0 3.4e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37_C PF11801.3 KFM07054.1 - 4.7e-07 29.8 1.8 0.0067 16.3 0.0 3.0 1 1 2 3 3 3 2 Tom37 C-terminal domain GST_C_2 PF13410.1 KFM07054.1 - 2.4e-06 27.3 0.0 5.1e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.4 KFM07054.1 - 0.00012 22.2 0.0 0.00025 21.2 0.0 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C PF00043.20 KFM07054.1 - 0.024 14.6 0.6 0.036 14.0 0.0 1.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain FAD-oxidase_C PF02913.14 KFM07056.1 - 9.5e-59 198.7 0.0 1.3e-58 198.2 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KFM07056.1 - 9.2e-38 128.8 0.0 6.3e-37 126.1 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KFM07056.1 - 0.064 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Berberine and berberine like TPR_2 PF07719.12 KFM07057.1 - 1.5e-15 55.8 32.9 3e-05 23.5 0.9 10.2 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_11 PF13414.1 KFM07057.1 - 2.6e-15 55.8 30.9 2.4e-06 27.1 0.5 6.5 5 1 1 6 6 6 4 TPR repeat TPR_16 PF13432.1 KFM07057.1 - 8.5e-14 51.7 30.5 0.00072 20.1 7.4 6.7 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFM07057.1 - 1.6e-12 47.6 24.9 0.0032 17.7 0.0 5.9 4 1 3 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.1 KFM07057.1 - 7.5e-10 38.6 32.9 0.002 18.0 1.2 7.6 4 2 4 9 9 9 5 Tetratricopeptide repeat TPR_1 PF00515.23 KFM07057.1 - 9.1e-10 37.7 29.4 0.0039 16.7 0.7 9.6 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_6 PF13174.1 KFM07057.1 - 2.3e-07 30.8 18.7 0.0082 16.5 0.1 7.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFM07057.1 - 6.1e-07 29.5 21.1 0.02 15.4 2.1 8.5 7 3 4 11 11 8 1 Tetratricopeptide repeat Apc3 PF12895.2 KFM07057.1 - 6.3e-07 29.4 30.4 0.012 15.7 5.1 5.5 4 2 3 7 7 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KFM07057.1 - 3e-06 26.6 14.6 0.016 14.9 2.4 6.8 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.9 KFM07057.1 - 1.1e-05 25.3 14.0 0.18 12.2 0.4 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 KFM07057.1 - 3.4e-05 23.6 15.2 0.56 10.2 0.8 7.5 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFM07057.1 - 0.00041 19.9 18.6 0.2 11.5 0.1 6.8 8 0 0 8 8 6 2 Tetratricopeptide repeat WXG100 PF06013.7 KFM07057.1 - 0.0087 16.0 0.6 0.031 14.2 0.1 2.2 2 0 0 2 2 2 1 Proteins of 100 residues with WXG PilJ PF13675.1 KFM07057.1 - 0.069 13.4 2.8 0.13 12.6 0.0 2.7 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term SNAP PF14938.1 KFM07057.1 - 0.07 12.2 11.6 0.53 9.3 0.2 3.3 2 1 0 3 3 3 0 Soluble NSF attachment protein, SNAP DUF285 PF03382.9 KFM07057.1 - 0.072 12.6 2.1 0.13 11.8 0.6 1.7 1 1 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 Fis1_TPR_C PF14853.1 KFM07057.1 - 0.93 9.4 13.6 3.3 7.6 1.4 4.6 3 1 1 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.1 KFM07057.1 - 9 6.2 24.5 0.15 11.8 2.7 4.7 2 1 2 4 4 4 0 Tetratricopeptide repeat PDEase_I PF00233.14 KFM07058.1 - 1.8e-72 243.9 1.9 2.2e-72 243.6 0.3 1.8 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.21 KFM07058.1 - 7.4e-48 162.5 0.0 9.6e-24 84.2 0.0 2.5 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.1 KFM07058.1 - 3.9e-22 78.7 0.0 3.8e-10 39.9 0.0 2.7 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.1 KFM07058.1 - 3.1e-20 73.1 0.0 4.2e-10 40.2 0.0 2.4 2 0 0 2 2 2 2 GAF domain HD PF01966.17 KFM07058.1 - 0.051 13.5 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 HD domain RRM_1 PF00076.17 KFM07059.1 - 1.8e-28 97.9 0.0 6.4e-14 51.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM07059.1 - 2.5e-18 65.8 0.0 2e-08 34.0 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM07059.1 - 1.5e-15 56.7 0.1 3.9e-06 26.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFM07059.1 - 8.5e-05 22.3 0.0 0.023 14.5 0.0 2.7 3 0 0 3 3 3 2 RNA binding motif Nup35_RRM_2 PF14605.1 KFM07059.1 - 0.13 12.0 0.1 14 5.5 0.0 2.6 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Oxysterol_BP PF01237.13 KFM07060.1 - 1.2e-130 435.1 0.0 1.2e-130 435.1 0.0 1.7 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 KFM07060.1 - 3.5e-13 49.4 0.4 8.8e-13 48.1 0.3 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 KFM07060.1 - 8.5e-06 25.9 2.5 0.00022 21.4 0.5 3.4 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 KFM07060.1 - 2.5e-05 24.4 0.7 2.5e-05 24.4 0.5 2.6 3 1 0 3 3 3 1 PH domain Gasdermin PF04598.7 KFM07061.1 - 3.3e-17 62.3 0.0 3.8e-17 62.1 0.0 1.0 1 0 0 1 1 1 1 Gasdermin family PH PF00169.24 KFM07062.1 - 4.8e-08 33.1 0.0 1e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KFM07062.1 - 1.4e-05 25.2 0.0 5.5e-05 23.3 0.0 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 KFM07062.1 - 5.7e-05 23.1 0.0 0.00014 21.8 0.0 1.7 2 0 0 2 2 2 1 Pleckstrin homology domain DNA_pol3_delta2 PF13177.1 KFM07062.1 - 0.027 14.1 0.6 0.04 13.5 0.4 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit PH_6 PF15406.1 KFM07062.1 - 0.042 13.9 0.0 0.2 11.7 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain Cmc1 PF08583.5 KFM07062.1 - 0.12 12.1 2.0 6.2 6.6 0.1 2.5 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like I-set PF07679.11 KFM07063.1 - 1.3e-77 255.7 5.7 2.6e-26 91.2 0.0 5.3 5 0 0 5 5 5 5 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM07063.1 - 1.6e-31 108.2 5.2 1.2e-07 31.7 0.0 5.4 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.20 KFM07063.1 - 2.6e-26 91.4 6.3 1.2e-08 34.8 0.0 6.0 6 0 0 6 6 6 4 Immunoglobulin domain V-set PF07686.12 KFM07063.1 - 1.2e-25 89.5 9.1 1.6e-07 31.1 0.1 6.6 5 3 0 5 5 5 5 Immunoglobulin V-set domain Ig_3 PF13927.1 KFM07063.1 - 5.9e-19 68.3 1.7 5.7e-08 33.1 0.1 5.8 5 0 0 5 5 5 3 Immunoglobulin domain C1-set PF07654.10 KFM07063.1 - 5.8e-08 32.6 1.1 0.0017 18.2 0.0 4.9 4 1 0 4 4 4 1 Immunoglobulin C1-set domain C2-set_2 PF08205.7 KFM07063.1 - 1.1e-07 31.6 5.0 0.0051 16.6 0.0 5.7 6 0 0 6 6 6 2 CD80-like C2-set immunoglobulin domain BiPBP_C PF06832.7 KFM07063.1 - 4.8e-07 29.6 0.0 2.9 7.8 0.0 4.7 4 1 0 4 4 4 2 Penicillin-Binding Protein C-terminus Family DUF2914 PF11141.3 KFM07063.1 - 0.039 13.4 0.9 5.4 6.6 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2914) I-set PF07679.11 KFM07064.1 - 6.2e-08 32.3 0.0 6.7e-08 32.2 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM07064.1 - 0.008 16.2 0.0 0.0089 16.1 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain DUF3922 PF13059.1 KFM07064.1 - 0.028 14.5 0.1 0.03 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3992) C2-set_2 PF08205.7 KFM07064.1 - 0.044 13.6 0.0 0.048 13.5 0.0 1.1 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain ig PF00047.20 KFM07064.1 - 0.14 12.2 0.0 0.2 11.8 0.0 1.3 1 1 0 1 1 1 0 Immunoglobulin domain I-set PF07679.11 KFM07065.1 - 1e-10 41.2 0.0 1.1e-10 41.2 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 KFM07065.1 - 1.3e-05 25.2 0.1 1.5e-05 24.9 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 KFM07065.1 - 0.00027 20.9 0.1 0.00029 20.9 0.1 1.0 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFM07065.1 - 0.0028 17.5 0.1 0.003 17.4 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.1 KFM07065.1 - 0.011 16.2 0.1 0.011 16.1 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain Receptor_2B4 PF11465.3 KFM07065.1 - 0.058 13.3 0.0 0.066 13.1 0.0 1.2 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 Herpes_gE PF02480.11 KFM07065.1 - 0.084 11.1 0.0 0.085 11.1 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E C2-set_2 PF08205.7 KFM07065.1 - 0.1 12.5 0.1 0.11 12.3 0.0 1.2 1 1 0 1 1 1 0 CD80-like C2-set immunoglobulin domain I-set PF07679.11 KFM07066.1 - 3.9e-09 36.2 0.0 4e-09 36.1 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM07066.1 - 0.0018 18.3 0.0 0.0019 18.2 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFM07066.1 - 0.012 15.7 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.11 KFM07067.1 - 1.6e-07 31.0 0.0 1.7e-07 30.9 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 KFM07067.1 - 0.0027 17.8 0.0 0.003 17.6 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 KFM07067.1 - 0.015 15.3 0.0 0.017 15.1 0.0 1.0 1 0 0 1 1 1 0 Immunoglobulin domain C2-set_2 PF08205.7 KFM07067.1 - 0.084 12.7 0.0 0.089 12.7 0.0 1.1 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain I-set PF07679.11 KFM07068.1 - 2.6e-07 30.3 0.0 2.8e-07 30.3 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM07068.1 - 0.04 14.0 0.0 0.043 13.9 0.0 1.0 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.11 KFM07069.1 - 5e-07 29.4 0.0 5.3e-07 29.3 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.1 KFM07069.1 - 0.0089 16.5 0.0 0.0091 16.4 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 KFM07069.1 - 0.027 14.5 0.0 0.031 14.3 0.0 1.0 1 0 0 1 1 1 0 Immunoglobulin domain ig PF00047.20 KFM07069.1 - 0.067 13.3 0.0 0.085 12.9 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.11 KFM07070.1 - 7.3e-08 32.1 0.0 7.6e-08 32.1 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM07070.1 - 0.0012 18.9 0.0 0.0014 18.7 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.7 KFM07070.1 - 0.063 13.1 0.0 0.069 13.0 0.0 1.1 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain I-set PF07679.11 KFM07071.1 - 7.6e-09 35.3 0.0 7.8e-09 35.2 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM07071.1 - 0.002 18.1 0.0 0.0021 18.1 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain fn3 PF00041.16 KFM07072.1 - 1.4e-104 342.4 8.4 9.5e-22 76.9 0.1 7.3 7 0 0 7 7 7 7 Fibronectin type III domain I-set PF07679.11 KFM07072.1 - 4.1e-33 113.0 1.6 5.1e-15 55.0 0.0 4.1 4 0 0 4 4 4 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM07072.1 - 7.3e-12 45.2 0.0 4.8e-06 26.6 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Tissue_fac PF01108.12 KFM07072.1 - 9.5e-08 31.7 0.0 0.021 14.5 0.0 5.2 5 0 0 5 5 5 1 Tissue factor SusE PF14292.1 KFM07072.1 - 2e-07 30.8 0.7 0.024 14.4 0.0 4.8 5 0 0 5 5 5 2 SusE outer membrane protein ig PF00047.20 KFM07072.1 - 5.4e-06 26.4 0.0 0.013 15.6 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 KFM07072.1 - 0.00015 22.2 0.0 0.012 16.1 0.0 3.4 3 0 0 3 3 3 1 Immunoglobulin domain Lipocalin_7 PF14651.1 KFM07072.1 - 0.0016 18.1 0.0 1.1 8.9 0.0 3.5 4 0 0 4 4 4 1 Lipocalin / cytosolic fatty-acid binding protein family V-set PF07686.12 KFM07072.1 - 0.0082 16.0 0.0 7.3 6.5 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin V-set domain I-set PF07679.11 KFM07073.1 - 4.6e-12 45.6 0.0 6.1e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM07073.1 - 4.4e-05 23.5 0.0 7.4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFM07073.1 - 0.00018 21.5 0.0 0.00032 20.7 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFM07073.1 - 0.0071 16.2 0.0 0.013 15.3 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 KFM07074.1 - 0 1835.5 58.8 5.3e-23 80.6 0.0 35.2 35 0 0 35 35 35 35 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM07074.1 - 2.5e-205 665.1 36.4 1.8e-14 53.6 0.1 32.7 32 2 2 34 34 34 28 Immunoglobulin domain Ig_3 PF13927.1 KFM07074.1 - 7.4e-130 423.4 19.9 9.1e-08 32.4 0.0 27.6 28 0 0 28 28 27 17 Immunoglobulin domain ig PF00047.20 KFM07074.1 - 2.2e-128 418.4 46.2 4.2e-07 29.9 0.0 32.8 33 1 0 33 33 33 25 Immunoglobulin domain V-set PF07686.12 KFM07074.1 - 1.9e-93 308.0 58.9 1.4e-05 24.9 0.1 33.8 23 6 8 33 33 33 21 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM07074.1 - 1.4e-52 175.5 11.4 0.004 17.0 0.0 23.5 25 0 0 25 25 25 13 CD80-like C2-set immunoglobulin domain C1-set PF07654.10 KFM07074.1 - 1.1e-30 105.3 40.1 0.00042 20.2 0.0 23.1 26 1 0 26 26 25 6 Immunoglobulin C1-set domain Titin_Z PF09042.6 KFM07074.1 - 3.1e-20 71.4 18.6 8e-16 57.3 5.4 2.9 2 0 0 2 2 2 2 Titin Z Receptor_2B4 PF11465.3 KFM07074.1 - 7.7e-15 54.7 24.7 0.12 12.2 0.1 16.4 17 1 1 18 18 17 3 Natural killer cell receptor 2B4 BiPBP_C PF06832.7 KFM07074.1 - 2.3e-14 53.0 0.4 0.52 10.2 0.0 15.2 21 1 0 21 21 21 2 Penicillin-Binding Protein C-terminus Family DUF3571 PF12095.3 KFM07074.1 - 0.0078 16.4 0.0 0.044 14.0 0.0 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3571) Spectrin PF00435.16 KFM07075.1 - 0.018 15.3 6.7 0.22 11.8 1.8 2.3 2 1 0 2 2 2 0 Spectrin repeat Coagulase PF08764.5 KFM07075.1 - 0.071 13.0 0.6 0.088 12.7 0.4 1.1 1 0 0 1 1 1 0 Staphylococcus aureus coagulase DUF3853 PF12964.2 KFM07075.1 - 0.099 12.4 0.3 0.28 11.0 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3853) Spectrin PF00435.16 KFM07076.1 - 0.11 12.7 17.4 0.3 11.3 1.9 3.0 2 1 0 2 2 2 0 Spectrin repeat DUF1024 PF06260.7 KFM07076.1 - 0.19 11.8 2.8 0.89 9.7 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1024) CRAL_TRIO_2 PF13716.1 KFM07077.1 - 1.3e-10 41.3 0.0 2.8e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Spectrin PF00435.16 KFM07077.1 - 7.4e-05 22.9 23.8 0.0011 19.2 0.3 4.8 4 1 1 5 5 5 2 Spectrin repeat Arch_ATPase PF01637.13 KFM07077.1 - 0.0028 17.3 0.2 0.0056 16.4 0.1 1.5 1 0 0 1 1 1 1 Archaeal ATPase zf-met PF12874.2 KFM07078.1 - 1.6e-28 97.9 24.4 4.1e-08 33.1 1.4 4.3 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFM07078.1 - 1.8e-23 82.0 19.6 2.8e-07 30.5 1.7 4.3 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFM07078.1 - 4.8e-10 39.4 10.1 0.12 12.5 0.2 4.2 4 0 0 4 4 4 4 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.7 KFM07078.1 - 1.8e-08 33.8 12.6 0.094 12.2 0.0 4.3 4 0 0 4 4 4 4 U1 zinc finger AKAP95 PF04988.7 KFM07078.1 - 9.3e-08 32.0 6.1 0.092 12.5 0.1 4.2 4 0 0 4 4 4 3 A-kinase anchoring protein 95 (AKAP95) zf-DBF PF07535.7 KFM07078.1 - 0.0029 17.2 10.8 0.29 10.8 0.7 4.2 4 0 0 4 4 4 1 DBF zinc finger Elf1 PF05129.8 KFM07078.1 - 0.074 12.7 6.2 4 7.1 0.1 3.9 4 0 0 4 4 4 0 Transcription elongation factor Elf1 like Lactococcin PF04369.8 KFM07078.1 - 0.13 12.2 0.3 0.79 9.6 0.1 2.2 1 1 1 2 2 2 0 Lactococcin-like family RNA_capsid PF03035.9 KFM07078.1 - 0.54 10.0 5.9 1.3 8.7 4.1 1.6 1 0 0 1 1 1 0 Calicivirus putative RNA polymerase/capsid protein zf-C2H2 PF00096.21 KFM07078.1 - 0.63 10.5 15.5 4 7.9 1.0 4.3 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM07078.1 - 1.4 9.4 12.8 24 5.5 0.2 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger MIF4G PF02854.14 KFM07079.1 - 3.9e-27 95.0 2.6 9.6e-27 93.7 1.3 2.1 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 KFM07079.1 - 5.7e-22 77.5 1.2 1.3e-21 76.3 0.9 1.7 1 0 0 1 1 1 1 MA3 domain SSP160 PF06933.6 KFM07079.1 - 1.1 7.1 12.7 1.7 6.5 8.8 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 UQ_con PF00179.21 KFM07081.1 - 3.1e-46 156.2 0.0 4.8e-46 155.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFM07081.1 - 0.00057 19.6 0.0 0.00087 19.0 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KFM07081.1 - 0.0019 18.1 0.1 0.0026 17.6 0.1 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KFM07081.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 UEV domain Herpes_LMP2 PF07415.6 KFM07081.1 - 3.2 6.2 5.3 4.7 5.6 3.7 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Integrin_beta PF00362.13 KFM07082.1 - 9.5e-193 640.8 0.7 1.3e-192 640.4 0.5 1.1 1 0 0 1 1 1 1 Integrin, beta chain EGF_2 PF07974.8 KFM07082.1 - 0.0002 21.4 13.3 0.0002 21.4 9.2 5.0 4 1 1 5 5 5 1 EGF-like domain CUB PF00431.15 KFM07083.1 - 1.9e-63 211.3 0.0 2.5e-32 111.2 0.0 2.7 2 0 0 2 2 2 2 CUB domain F5_F8_type_C PF00754.20 KFM07083.1 - 1.3e-53 180.2 3.1 6.1e-27 94.0 0.1 2.3 2 0 0 2 2 2 2 F5/8 type C domain MAM PF00629.18 KFM07083.1 - 3.4e-39 134.1 1.0 9.1e-39 132.8 0.7 1.7 1 0 0 1 1 1 1 MAM domain DUF3481 PF11980.3 KFM07083.1 - 2.6e-29 100.8 0.1 9.3e-29 99.0 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3481) PDZ PF00595.19 KFM07085.1 - 6.7e-38 128.7 6.3 1.9e-15 56.7 0.1 3.7 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) DUF3534 PF12053.3 KFM07085.1 - 1.9e-27 95.9 0.3 1.9e-27 95.9 0.2 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3534) PDZ_2 PF13180.1 KFM07085.1 - 7.5e-15 54.5 0.6 2.1e-06 27.5 0.0 3.7 3 0 0 3 3 3 3 PDZ domain bZIP_1 PF00170.16 KFM07087.1 - 2.1e-20 72.4 12.6 3.4e-20 71.7 8.5 1.6 2 0 0 2 2 2 1 bZIP transcription factor pKID PF02173.12 KFM07087.1 - 1.1e-18 66.2 1.4 2.6e-18 64.9 0.9 1.7 1 0 0 1 1 1 1 pKID domain bZIP_2 PF07716.10 KFM07087.1 - 1.2e-07 31.4 10.8 2e-07 30.7 7.5 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KFM07087.1 - 0.0018 18.5 6.2 0.0034 17.6 4.3 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor Cyclin_N PF00134.18 KFM07088.1 - 1.5e-14 53.6 0.2 3e-14 52.6 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 KFM07088.1 - 7.1e-13 49.2 0.1 1.1e-12 48.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin Frizzled PF01534.12 KFM07089.1 - 4.3e-113 377.4 2.9 5.2e-113 377.1 2.0 1.0 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.17 KFM07089.1 - 6.9e-29 100.5 0.3 6.9e-29 100.5 0.2 1.6 2 0 0 2 2 2 1 Fz domain Dicty_CAR PF05462.6 KFM07089.1 - 0.00025 20.0 2.3 0.00042 19.3 1.6 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor GAS2 PF02187.12 KFM07090.1 - 0.076 12.7 0.0 0.078 12.7 0.0 1.1 1 0 0 1 1 1 0 Growth-Arrest-Specific Protein 2 Domain zf-C2H2 PF00096.21 KFM07091.1 - 1.1e-12 47.4 31.8 0.00019 21.6 6.3 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM07091.1 - 8e-11 41.6 13.3 8.5e-07 28.9 4.6 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM07091.1 - 1.7e-07 31.0 29.5 0.0097 16.1 1.1 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KFM07091.1 - 0.35 11.1 0.1 0.35 11.1 0.0 3.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 KFM07091.1 - 3.4 7.9 10.0 11 6.2 1.4 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding M16C_assoc PF08367.6 KFM07092.1 - 1.9e-84 282.3 0.0 3.7e-84 281.4 0.0 1.5 2 0 0 2 2 2 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 KFM07092.1 - 5.1e-32 111.0 0.0 9.8e-21 74.2 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KFM07092.1 - 1.6e-10 40.8 0.2 7.6e-05 22.5 0.0 4.5 5 0 0 5 5 5 2 Insulinase (Peptidase family M16) KMP11 PF03037.11 KFM07092.1 - 7.7 7.1 11.0 0.37 11.4 1.3 3.1 3 0 0 3 3 3 0 Kinetoplastid membrane protein 11 A_deamin PF02137.13 KFM07093.1 - 1e-115 386.7 0.0 1.6e-115 386.1 0.0 1.3 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain dsrm PF00035.20 KFM07093.1 - 1.2e-25 89.8 0.2 5.4e-12 46.1 0.0 2.8 2 0 0 2 2 2 2 Double-stranded RNA binding motif DND1_DSRM PF14709.1 KFM07093.1 - 0.0044 17.2 0.8 1.4 9.2 0.0 2.9 2 1 0 2 2 2 2 double strand RNA binding domain from DEAD END PROTEIN 1 WD40 PF00400.27 KFM07094.1 - 1.1e-36 123.3 22.0 7.6e-08 31.9 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat HALZ PF02183.13 KFM07094.1 - 0.0029 17.2 0.5 0.0062 16.2 0.4 1.6 1 0 0 1 1 1 1 Homeobox associated leucine zipper DUF972 PF06156.8 KFM07094.1 - 0.052 13.8 1.2 0.12 12.7 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DivIVA PF05103.8 KFM07094.1 - 0.084 12.9 0.5 0.17 11.9 0.4 1.4 1 0 0 1 1 1 0 DivIVA protein NUDIX PF00293.23 KFM07095.1 - 1.9e-25 89.0 0.0 2.4e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NOG1 PF06858.9 KFM07096.1 - 9.4e-30 102.2 0.1 2.1e-29 101.1 0.1 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.6 KFM07096.1 - 1.4e-23 82.3 5.3 2.8e-23 81.3 2.2 2.6 2 0 0 2 2 2 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.18 KFM07096.1 - 6.6e-20 71.2 0.0 2.5e-19 69.3 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFM07096.1 - 1.7e-11 43.6 0.0 4.2e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 KFM07096.1 - 8.9e-08 32.6 0.8 3.5e-07 30.7 0.0 2.5 3 0 0 3 3 2 1 Miro-like protein Ras PF00071.17 KFM07096.1 - 1.6e-05 24.3 0.0 4.6e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 Ras family AIG1 PF04548.11 KFM07096.1 - 9.2e-05 21.6 0.5 0.0008 18.5 0.0 2.6 3 0 0 3 3 3 1 AIG1 family Gtr1_RagA PF04670.7 KFM07096.1 - 0.00074 18.7 0.3 0.011 14.9 0.0 2.5 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Dynamin_N PF00350.18 KFM07096.1 - 0.0022 17.8 5.6 0.32 10.7 0.0 3.3 2 2 1 3 3 2 2 Dynamin family SRPRB PF09439.5 KFM07096.1 - 0.0055 15.9 0.1 0.043 13.0 0.0 2.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 KFM07096.1 - 0.022 13.9 0.0 0.15 11.2 0.0 2.2 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 KFM07096.1 - 0.051 13.1 0.0 8.8 5.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain MobB PF03205.9 KFM07096.1 - 0.068 12.8 0.3 0.33 10.6 0.0 2.4 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B PLRV_ORF5 PF01690.12 KFM07096.1 - 1.6 7.7 9.7 2.2 7.3 6.7 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein La PF05383.12 KFM07097.1 - 2.4e-18 65.6 0.2 4.5e-18 64.7 0.1 1.5 1 0 0 1 1 1 1 La domain RRM_5 PF13893.1 KFM07097.1 - 0.00039 20.2 0.1 0.00072 19.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM07097.1 - 0.00043 20.2 0.0 0.00097 19.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PWWP PF00855.12 KFM07098.1 - 2e-12 47.1 0.5 2e-12 47.1 0.3 4.3 3 2 0 3 3 3 1 PWWP domain Bromodomain PF00439.20 KFM07098.1 - 7.8e-12 44.9 0.3 2e-11 43.6 0.2 1.8 1 0 0 1 1 1 1 Bromodomain PHD PF00628.24 KFM07098.1 - 0.00011 21.8 9.3 0.00011 21.8 6.4 4.5 3 2 1 4 4 4 1 PHD-finger zf-MYND PF01753.13 KFM07098.1 - 0.0022 17.8 21.8 0.0022 17.8 15.1 4.1 3 1 0 3 3 3 1 MYND finger Spore_III_AB PF09548.5 KFM07098.1 - 0.41 10.3 4.5 1 9.0 3.1 1.6 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Mitofilin PF09731.4 KFM07098.1 - 5.3 5.5 23.2 9.8 4.6 16.1 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Yae1_N PF09811.4 KFM07099.1 - 4.3e-08 32.5 36.3 0.024 14.1 6.4 4.9 1 1 2 3 3 3 3 Essential protein Yae1, N terminal 7tm_2 PF00002.19 KFM07100.1 - 9.3e-83 277.0 13.3 1.1e-82 276.7 9.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 KFM07100.1 - 6.8e-21 74.0 2.4 6.8e-21 74.0 1.6 2.4 2 0 0 2 2 2 1 Hormone receptor domain DUF1129 PF06570.6 KFM07100.1 - 0.14 11.4 1.5 0.37 10.0 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) C2 PF00168.25 KFM07101.1 - 1.4e-48 162.6 0.0 5.4e-18 64.6 0.0 3.6 3 0 0 3 3 3 3 C2 domain Condensin2nSMC PF12422.3 KFM07102.1 - 3.2e-69 231.4 3.2 2.4e-52 176.6 0.4 4.5 5 0 0 5 5 5 2 Condensin II non structural maintenance of chromosomes subunit HEAT PF02985.17 KFM07102.1 - 2.9e-08 33.1 1.1 1.2 9.4 0.0 5.6 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.1 KFM07102.1 - 1.7e-06 28.2 0.0 0.017 15.3 0.0 3.0 1 1 1 2 2 2 2 HEAT repeats DUF577 PF04510.7 KFM07102.1 - 0.0001 22.0 5.7 0.28 10.8 0.0 4.8 5 0 0 5 5 5 2 Family of unknown function (DUF577) Adaptin_N PF01602.15 KFM07102.1 - 0.00011 20.7 1.4 0.00017 20.0 0.1 2.1 2 0 0 2 2 2 1 Adaptin N terminal region RPAP3_C PF13877.1 KFM07102.1 - 0.011 15.7 0.6 2.7 8.0 0.1 3.5 3 0 0 3 3 3 0 Potential Monad-binding region of RPAP3 Vac14_Fab1_bd PF12755.2 KFM07102.1 - 0.068 13.5 0.1 0.99 9.8 0.0 3.1 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Glyco_hydro_31 PF01055.21 KFM07104.1 - 4.5e-72 243.2 0.7 5e-72 243.1 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Glyco_hydro_66 PF13199.1 KFM07104.1 - 0.00076 18.0 0.0 0.001 17.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 66 Trefoil PF00088.13 KFM07105.1 - 9.7e-07 28.3 4.2 1.5e-06 27.7 2.9 1.3 1 0 0 1 1 1 1 Trefoil (P-type) domain Myosin_tail_1 PF01576.14 KFM07106.1 - 3.5e-125 418.7 82.1 3.9e-125 418.6 56.9 1.0 1 0 0 1 1 1 1 Myosin tail DUF3851 PF12962.2 KFM07106.1 - 0.053 13.5 1.9 0.12 12.3 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3851) Filament PF00038.16 KFM07106.1 - 0.62 9.4 64.7 0.078 12.4 30.7 2.8 1 1 1 2 2 2 0 Intermediate filament protein IncA PF04156.9 KFM07106.1 - 0.76 9.3 70.1 0.31 10.5 13.5 4.1 1 1 3 4 4 4 0 IncA protein Tropomyosin PF00261.15 KFM07106.1 - 1.3 8.0 75.7 0.035 13.1 7.6 4.1 1 1 3 4 4 4 0 Tropomyosin Mga PF05043.8 KFM07106.1 - 1.4 9.2 5.7 9.6 6.5 0.3 3.1 3 0 0 3 3 3 0 Mga helix-turn-helix domain Reo_sigmaC PF04582.7 KFM07106.1 - 2 7.5 19.8 0.65 9.1 3.8 3.1 1 1 2 3 3 3 0 Reovirus sigma C capsid protein wnt PF00110.14 KFM07108.1 - 4.4e-126 420.2 24.7 6.4e-126 419.7 17.1 1.2 1 0 0 1 1 1 1 wnt family FAD_binding_1 PF00667.15 KFM07109.1 - 1.7e-45 155.1 0.0 2.6e-45 154.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KFM07109.1 - 2.1e-28 99.1 0.0 3.4e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KFM07109.1 - 2.7e-10 40.7 0.0 7e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 KFM07109.1 - 1.9e-06 27.9 0.0 3.5e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_3 PF12641.2 KFM07109.1 - 0.19 11.1 0.0 0.35 10.2 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain FAST_1 PF06743.10 KFM07110.1 - 1.7e-22 78.8 3.0 1.7e-22 78.8 2.1 3.8 3 1 2 5 5 5 1 FAST kinase-like protein, subdomain 1 FAST_2 PF08368.7 KFM07110.1 - 1.1e-16 60.9 2.4 1.5e-16 60.4 0.1 2.5 3 0 0 3 3 3 1 FAST kinase-like protein, subdomain 2 RAP PF08373.5 KFM07110.1 - 3.7e-13 49.0 0.0 8.3e-13 47.9 0.0 1.6 1 0 0 1 1 1 1 RAP domain RNA_pol_N PF01194.12 KFM07110.1 - 0.013 15.5 0.0 0.05 13.6 0.0 2.0 2 0 0 2 2 2 0 RNA polymerases N / 8 kDa subunit RasGAP PF00616.14 KFM07110.1 - 0.48 10.0 3.2 0.78 9.3 0.2 2.5 3 0 0 3 3 3 0 GTPase-activator protein for Ras-like GTPase DUF4541 PF15074.1 KFM07111.1 - 1.5e-22 79.9 0.0 1.5e-22 79.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4541) Guanylate_cyc PF00211.15 KFM07112.1 - 2.7e-121 401.7 0.6 2.7e-65 219.1 0.1 2.2 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain DUF1053 PF06327.9 KFM07112.1 - 9.1e-27 93.3 0.4 1.8e-26 92.4 0.3 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1053) HNOBA PF07701.9 KFM07112.1 - 0.00049 19.3 1.1 0.031 13.5 0.3 2.4 2 0 0 2 2 2 2 Heme NO binding associated Steroid_dh PF02544.11 KFM07113.1 - 1.5e-43 148.1 0.3 1.7e-43 147.9 0.2 1.0 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 KFM07113.1 - 1e-05 24.9 0.1 1.1e-05 24.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Nol1_Nop2_Fmu PF01189.12 KFM07114.1 - 1.5e-36 126.2 0.1 9.1e-20 71.1 0.0 3.2 2 1 1 3 3 3 3 NOL1/NOP2/sun family FtsJ PF01728.14 KFM07114.1 - 0.041 13.8 0.0 0.084 12.8 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase UQ_con PF00179.21 KFM07115.1 - 6.6e-11 41.8 0.0 1.2e-10 41.0 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFM07115.1 - 3.8e-05 23.4 0.0 4.5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B Med10 PF09748.4 KFM07116.1 - 4.3e-30 104.1 0.2 4.6e-30 104.0 0.1 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex PNP_UDP_1 PF01048.15 KFM07117.1 - 9.2e-23 80.4 0.0 1.1e-22 80.2 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DUF713 PF05218.9 KFM07118.1 - 0.029 14.1 0.6 0.032 13.9 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF713) Interferon PF00143.14 KFM07118.1 - 0.12 12.2 0.8 0.19 11.5 0.5 1.4 1 1 1 2 2 2 0 Interferon alpha/beta domain VWA_N PF08399.6 KFM07119.1 - 5.7e-30 104.4 0.1 4.2e-29 101.6 0.0 2.3 2 0 0 2 2 2 1 VWA N-terminal Cache_1 PF02743.13 KFM07119.1 - 1.2e-16 59.9 0.1 6.1e-10 38.5 0.0 3.0 2 1 0 2 2 2 2 Cache domain VWA PF00092.23 KFM07119.1 - 4.2e-05 23.3 2.0 7.8e-05 22.4 1.4 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 KFM07119.1 - 0.015 15.0 0.1 0.035 13.7 0.0 1.7 1 0 0 1 1 1 0 von Willebrand factor type A domain RRM_1 PF00076.17 KFM07120.1 - 1.2e-24 85.7 4.1 1.8e-13 49.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM07120.1 - 4.7e-18 64.9 0.1 3e-07 30.3 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM07120.1 - 4.8e-18 64.7 1.5 1.3e-05 24.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase_Tyr PF07714.12 KFM07121.1 - 3.1e-142 472.1 0.0 8.4e-84 280.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 KFM07121.1 - 6.3e-72 241.8 0.0 1.4e-46 158.8 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.1 KFM07121.1 - 2.3e-06 26.8 0.0 0.00078 18.4 0.0 2.4 2 0 0 2 2 2 2 Kinase-like SH2 PF00017.19 KFM07121.1 - 1.6e-05 24.6 0.0 6.4e-05 22.6 0.0 2.2 1 0 0 1 1 1 1 SH2 domain APH PF01636.18 KFM07121.1 - 0.24 11.1 0.0 1.6 8.4 0.0 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family ADK PF00406.17 KFM07122.1 - 1.6e-15 57.3 0.0 1.8e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 KFM07122.1 - 2.7e-15 55.7 0.0 5e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid PTEN_C2 PF10409.4 KFM07123.1 - 1.1e-25 89.9 0.0 2.1e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DnaJ PF00226.26 KFM07123.1 - 5.2e-07 29.3 0.0 1.4e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Y_phosphatase PF00102.22 KFM07123.1 - 0.0026 17.1 0.1 0.0048 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Vps55 PF04133.9 KFM07124.1 - 4.1e-39 133.0 4.4 4.6e-39 132.8 3.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 YwiC PF14256.1 KFM07124.1 - 0.94 9.5 5.7 1.4 9.0 3.5 1.5 1 1 0 1 1 1 0 YwiC-like protein MtN3_slv PF03083.11 KFM07124.1 - 6 6.8 6.9 2.5 8.0 0.4 2.5 1 1 1 2 2 2 0 Sugar efflux transporter for intercellular exchange Lep_receptor_Ig PF06328.6 KFM07125.1 - 4.2e-30 103.4 1.5 1.2e-29 101.9 0.4 2.4 2 0 0 2 2 2 1 Ig-like C2-type domain fn3 PF00041.16 KFM07125.1 - 1.6e-11 44.1 5.9 0.0045 17.0 0.0 4.8 4 0 0 4 4 4 4 Fibronectin type III domain PDEase_I PF00233.14 KFM07128.1 - 1.4e-106 355.6 6.9 1.4e-106 355.6 4.8 1.8 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase DFP PF04127.10 KFM07128.1 - 0.14 11.7 2.6 0.088 12.4 0.2 1.8 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein muHD PF10291.4 KFM07129.1 - 1.7e-73 247.0 0.0 2.3e-73 246.5 0.0 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Adap_comp_sub PF00928.16 KFM07129.1 - 1.2e-06 27.8 0.0 2e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Tctex-1 PF03645.8 KFM07130.1 - 4.6e-26 90.6 0.0 5e-26 90.5 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family Insulin PF00049.13 KFM07131.1 - 0.0058 17.3 0.1 0.0074 17.0 0.0 1.2 1 0 0 1 1 1 1 Insulin/IGF/Relaxin family WD40 PF00400.27 KFM07132.1 - 2.3e-16 58.9 4.9 8.7e-08 31.7 0.1 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF3312 PF11768.3 KFM07132.1 - 0.00067 18.0 0.0 0.0014 16.9 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3312) DUF1830 PF08865.6 KFM07132.1 - 0.0099 15.4 0.2 0.048 13.2 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1830) DUF2147 PF09917.4 KFM07132.1 - 0.029 14.6 0.0 0.093 13.0 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2147) ELM2 PF01448.19 KFM07133.1 - 1.7e-12 47.7 1.8 2.7e-12 47.1 0.0 2.4 2 0 0 2 2 2 1 ELM2 domain Myb_DNA-binding PF00249.26 KFM07133.1 - 0.00012 22.0 0.1 0.00026 20.9 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain TPT PF03151.11 KFM07134.1 - 4e-12 46.0 14.8 4.3e-12 45.9 8.7 1.9 1 1 1 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KFM07134.1 - 0.00032 19.7 15.2 0.00048 19.1 10.6 1.3 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KFM07134.1 - 0.0082 16.1 16.6 0.19 11.7 1.4 2.2 2 0 0 2 2 2 2 EamA-like transporter family PglZ PF08665.7 KFM07134.1 - 0.069 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 PglZ domain HABP4_PAI-RBP1 PF04774.10 KFM07137.1 - 2e-36 124.6 11.3 2e-36 124.6 7.8 2.2 3 0 0 3 3 3 1 Hyaluronan / mRNA binding family G-gamma PF00631.17 KFM07138.1 - 7.8e-18 63.9 0.1 9.1e-18 63.7 0.0 1.0 1 0 0 1 1 1 1 GGL domain CP12 PF02672.10 KFM07138.1 - 0.13 12.6 0.1 0.2 12.1 0.1 1.2 1 0 0 1 1 1 0 CP12 domain Ras PF00071.17 KFM07139.1 - 9.8e-47 158.3 0.1 1.2e-46 158.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM07139.1 - 9.4e-24 84.1 0.4 2e-23 83.1 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFM07139.1 - 2.9e-07 29.8 0.0 4.7e-07 29.2 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFM07139.1 - 0.00025 20.5 0.1 0.00067 19.1 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KFM07139.1 - 0.00055 19.1 1.1 0.0027 16.9 0.0 1.9 1 1 0 2 2 2 1 Signal recognition particle receptor beta subunit ArgK PF03308.11 KFM07139.1 - 0.00086 18.1 0.3 0.17 10.6 0.1 2.2 2 0 0 2 2 2 2 ArgK protein MMR_HSR1 PF01926.18 KFM07139.1 - 0.0016 18.3 0.0 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KFM07139.1 - 0.0035 17.4 0.0 0.012 15.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 KFM07139.1 - 0.01 15.1 0.3 0.076 12.2 0.0 2.1 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_32 PF13654.1 KFM07139.1 - 0.013 14.2 1.2 0.3 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 KFM07139.1 - 0.023 13.9 0.7 0.058 12.5 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 KFM07139.1 - 0.028 13.9 0.2 0.042 13.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain Glyco_tran_WbsX PF14307.1 KFM07139.1 - 0.029 13.5 0.2 0.038 13.1 0.1 1.1 1 0 0 1 1 1 0 Glycosyltransferase WbsX Arch_ATPase PF01637.13 KFM07139.1 - 0.054 13.1 0.1 0.09 12.4 0.1 1.7 1 1 0 1 1 1 0 Archaeal ATPase AAA_28 PF13521.1 KFM07139.1 - 0.071 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain FGF PF00167.13 KFM07139.1 - 0.08 12.7 0.2 0.14 11.8 0.2 1.4 1 0 0 1 1 1 0 Fibroblast growth factor AAA_16 PF13191.1 KFM07139.1 - 0.087 12.8 0.5 0.18 11.7 0.3 1.9 1 1 0 1 1 1 0 AAA ATPase domain MIG-14_Wnt-bd PF06664.7 KFM07140.1 - 3.4e-92 308.4 18.1 5e-92 307.9 12.6 1.3 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion Carboxyl_trans PF01039.17 KFM07141.1 - 2.9e-101 339.2 0.0 3.6e-101 338.9 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain RPE65 PF03055.10 KFM07143.1 - 2.2e-123 412.4 0.0 2.5e-123 412.2 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DEP PF00610.16 KFM07144.1 - 3e-18 65.3 0.0 1e-17 63.6 0.0 2.0 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGAP PF00620.22 KFM07144.1 - 0.0019 17.8 10.0 0.16 11.6 0.1 3.8 5 1 0 5 5 5 2 RhoGAP domain LRR_4 PF12799.2 KFM07145.1 - 9e-47 156.0 50.9 4.6e-08 32.4 0.4 9.6 5 3 3 9 9 9 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM07145.1 - 6.6e-37 125.0 39.9 2e-08 33.8 1.4 6.8 5 1 1 6 6 6 6 Leucine rich repeat LRR_1 PF00560.28 KFM07145.1 - 4.6e-21 71.5 45.9 0.046 13.7 0.3 16.2 15 1 1 16 16 16 6 Leucine Rich Repeat PDZ PF00595.19 KFM07145.1 - 1.9e-16 59.9 0.0 3.6e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) LRR_7 PF13504.1 KFM07145.1 - 1.1e-12 45.8 44.1 0.81 10.1 0.4 16.0 15 1 1 16 16 16 4 Leucine rich repeat PDZ_2 PF13180.1 KFM07145.1 - 1e-05 25.3 0.0 2.6e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 PDZ domain LRR_5 PF13306.1 KFM07145.1 - 2.1e-05 24.1 1.2 0.011 15.4 0.1 3.7 2 1 2 4 4 4 1 Leucine rich repeats (6 copies) LRR_9 PF14580.1 KFM07145.1 - 0.012 15.1 12.2 0.34 10.4 0.3 4.6 1 1 4 6 6 6 0 Leucine-rich repeat LRR_6 PF13516.1 KFM07145.1 - 0.062 13.3 30.1 2.7 8.3 0.0 8.9 9 1 0 9 9 9 0 Leucine Rich repeat LRR_4 PF12799.2 KFM07146.1 - 4.1e-64 211.3 73.8 3.9e-09 35.9 0.6 11.3 4 3 7 13 13 13 13 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM07146.1 - 1.4e-61 204.1 123.0 4.9e-13 48.6 3.5 9.3 2 2 12 14 14 14 13 Leucine rich repeat LRR_1 PF00560.28 KFM07146.1 - 2.2e-37 121.3 61.7 0.00031 20.3 0.4 18.7 19 0 0 19 19 19 12 Leucine Rich Repeat LRR_7 PF13504.1 KFM07146.1 - 2.3e-21 72.1 63.4 0.0081 16.1 0.2 16.9 18 0 0 18 18 18 8 Leucine rich repeat LRR_6 PF13516.1 KFM07146.1 - 1.4e-12 46.2 55.1 0.024 14.6 0.1 16.9 17 2 1 18 18 18 5 Leucine Rich repeat LRR_9 PF14580.1 KFM07146.1 - 1.4e-06 27.9 20.7 0.035 13.6 1.2 5.3 2 2 3 5 5 5 4 Leucine-rich repeat Stk19 PF10494.4 KFM07146.1 - 0.04 13.2 3.1 0.87 8.9 0.1 2.7 2 1 0 2 2 2 0 Serine-threonine protein kinase 19 Dynactin_p22 PF07426.6 KFM07146.1 - 0.3 10.3 6.2 2.2 7.5 0.2 4.1 3 1 1 4 4 4 0 Dynactin subunit p22 RRM_5 PF13893.1 KFM07147.1 - 0.036 13.9 0.0 0.072 12.9 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GPCR_chapero_1 PF11904.3 KFM07148.1 - 5.8e-80 268.6 0.2 8.2e-80 268.2 0.1 1.1 1 0 0 1 1 1 1 GPCR-chaperone Ank PF00023.25 KFM07148.1 - 1.2e-11 43.8 0.4 1.1e-07 31.2 0.5 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KFM07148.1 - 1.4e-10 41.3 0.1 2.5e-10 40.5 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFM07148.1 - 8.8e-08 32.4 0.1 2e-07 31.3 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM07148.1 - 9.6e-08 32.0 0.3 2.7e-07 30.5 0.2 1.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM07148.1 - 7.6e-07 28.7 0.1 0.00087 19.3 0.2 2.9 2 0 0 2 2 2 2 Ankyrin repeat RVT_1 PF00078.22 KFM07149.1 - 0.011 15.0 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Cys_Met_Meta_PP PF01053.15 KFM07150.1 - 1.8e-147 490.6 0.0 2.1e-147 490.4 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KFM07150.1 - 8.3e-08 31.5 0.2 1.1e-07 31.1 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KFM07150.1 - 3.3e-07 29.6 0.1 4.9e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 KFM07150.1 - 1.8e-06 26.9 0.2 2.6e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V GDC-P PF02347.11 KFM07150.1 - 0.00049 18.9 0.0 0.00078 18.2 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein zf-RanBP PF00641.13 KFM07151.1 - 1.4e-09 36.8 19.6 1.2e-06 27.4 6.6 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.2 KFM07151.1 - 1.1 9.1 9.6 9.1 6.1 1.6 2.2 1 1 1 2 2 2 0 Double zinc ribbon GCC2_GCC3 PF07699.8 KFM07151.1 - 3.7 7.2 8.0 1.7 8.3 0.1 3.3 2 1 0 2 2 2 0 GCC2 and GCC3 DUF936 PF06075.7 KFM07151.1 - 4 6.2 42.2 5.3 5.8 29.3 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) I-set PF07679.11 KFM07152.1 - 8.4e-27 92.8 0.1 1.7e-12 46.9 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.1 KFM07152.1 - 7.4e-25 87.2 1.4 9.9e-12 45.1 0.0 2.9 2 1 1 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.1 KFM07152.1 - 3.5e-24 84.7 0.1 2.3e-11 43.6 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 KFM07152.1 - 9.4e-15 54.5 1.9 1.9e-08 34.2 0.0 3.1 3 1 0 3 3 3 2 Immunoglobulin domain V-set PF07686.12 KFM07152.1 - 1.9e-08 34.1 0.4 0.0015 18.4 0.0 3.5 2 2 1 3 3 3 2 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM07152.1 - 1.5e-05 24.7 0.0 0.19 11.6 0.0 2.5 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain GAS2 PF02187.12 KFM07153.1 - 5.1e-36 122.2 0.2 8.6e-36 121.5 0.2 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.26 KFM07153.1 - 4.7e-08 33.0 0.0 7.7e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain MFS_1 PF07690.11 KFM07154.1 - 5.2e-50 170.1 24.8 1.6e-48 165.2 15.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Anoctamin PF04547.7 KFM07155.1 - 2.5e-161 537.3 21.2 3.1e-161 537.0 14.7 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel RVT_1 PF00078.22 KFM07156.1 - 1.8e-20 73.1 0.0 2.6e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EGF_CA PF07645.10 KFM07157.1 - 5e-26 90.4 55.4 5.7e-11 42.2 4.1 11.3 10 2 2 12 12 6 4 Calcium-binding EGF domain VWC PF00093.13 KFM07157.1 - 3.5e-20 71.8 77.6 1.2e-10 41.3 10.4 9.9 6 1 2 8 8 7 5 von Willebrand factor type C domain EGF_3 PF12947.2 KFM07157.1 - 3.2e-12 46.2 37.8 2.1e-09 37.2 9.5 11.0 10 0 0 10 10 8 4 EGF domain Laminin_G_2 PF02210.19 KFM07157.1 - 4.4e-09 36.4 0.0 7.4e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain cEGF PF12662.2 KFM07157.1 - 5.3e-09 35.5 11.2 9.8e-08 31.5 1.7 11.3 12 0 0 12 12 11 5 Complement Clr-like EGF-like EGF PF00008.22 KFM07157.1 - 5.4e-07 29.4 36.5 0.0004 20.2 2.8 11.3 13 1 0 13 13 11 4 EGF-like domain Laminin_G_3 PF13385.1 KFM07157.1 - 2.4e-06 27.8 0.0 3.9e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily TILa PF12714.2 KFM07157.1 - 4.8e-06 26.2 5.4 4.8e-06 26.2 3.8 11.4 6 4 5 11 11 6 3 TILa domain Laminin_G_1 PF00054.18 KFM07157.1 - 8.6e-05 22.5 0.0 0.00022 21.2 0.0 1.6 1 1 0 1 1 1 1 Laminin G domain hEGF PF12661.2 KFM07157.1 - 0.00034 20.4 3.0 0.00034 20.4 2.1 12.3 12 0 0 12 12 10 2 Human growth factor-like EGF EGF_2 PF07974.8 KFM07157.1 - 0.002 18.2 14.2 0.002 18.2 9.8 13.2 10 3 1 11 11 10 2 EGF-like domain FXa_inhibition PF14670.1 KFM07157.1 - 0.017 15.2 7.4 0.017 15.2 5.1 11.1 8 3 3 11 11 7 0 Coagulation Factor Xa inhibitory site SNF PF00209.13 KFM07159.1 - 8.7e-123 410.5 17.3 9.7e-123 410.3 12.0 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family PrmA PF06325.8 KFM07160.1 - 6.1e-12 45.2 0.1 1e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 KFM07160.1 - 2.3e-10 40.2 0.1 4.9e-10 39.1 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KFM07160.1 - 1.4e-09 37.0 0.1 1.9e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.2 KFM07160.1 - 1.5e-09 38.4 0.2 5.9e-09 36.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFM07160.1 - 2e-08 34.2 0.0 6e-08 32.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFM07160.1 - 2.8e-08 34.1 0.0 8.1e-08 32.6 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 KFM07160.1 - 9.3e-07 28.3 0.0 2.3e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 KFM07160.1 - 1.6e-06 27.9 0.0 4e-06 26.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFM07160.1 - 1.3e-05 25.4 0.1 3.8e-05 23.9 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Met_10 PF02475.11 KFM07160.1 - 9.5e-05 22.0 0.2 0.00019 21.0 0.1 1.4 1 0 0 1 1 1 1 Met-10+ like-protein PRMT5 PF05185.11 KFM07160.1 - 0.00011 21.2 0.4 0.00043 19.3 0.3 1.8 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_12 PF08242.7 KFM07160.1 - 0.00015 22.2 0.0 0.00037 20.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KFM07160.1 - 0.00021 21.3 0.0 0.0005 20.1 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 KFM07160.1 - 0.00028 19.9 0.0 0.00098 18.2 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase TehB PF03848.9 KFM07160.1 - 0.004 16.3 0.1 0.0069 15.5 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.14 KFM07160.1 - 0.0048 16.4 0.1 0.0082 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) ATP-synt_B PF00430.13 KFM07160.1 - 0.0081 15.9 0.1 0.013 15.2 0.1 1.2 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) Methyltransf_16 PF10294.4 KFM07160.1 - 0.024 14.1 0.0 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.15 KFM07160.1 - 0.028 13.4 0.0 0.046 12.7 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.10 KFM07160.1 - 0.036 13.4 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DUF1707 PF08044.6 KFM07160.1 - 0.076 12.7 2.3 0.15 11.8 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) Methyltransf_24 PF13578.1 KFM07160.1 - 0.097 13.5 0.0 0.48 11.2 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Paralemmin PF03285.10 KFM07161.1 - 1.8e-43 149.0 14.7 3.1e-43 148.2 10.2 1.4 1 1 0 1 1 1 1 Paralemmin Med4 PF10018.4 KFM07161.1 - 0.53 9.6 5.2 0.22 10.8 1.7 1.8 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 TMCO5 PF14992.1 KFM07161.1 - 8 5.5 11.3 4.8 6.2 1.9 2.9 3 0 0 3 3 3 0 TMCO5 family AKAP2_C PF15304.1 KFM07162.1 - 2.1e-19 70.3 12.5 2.1e-19 70.3 8.6 2.8 2 1 0 2 2 2 1 A-kinase anchor protein 2 C-terminus Misat_Tub_SegII PF10644.4 KFM07162.1 - 0.017 15.1 0.4 0.078 13.0 0.0 2.4 2 0 0 2 2 2 0 Misato Segment II tubulin-like domain RII_binding_1 PF10522.4 KFM07162.1 - 0.031 14.3 0.4 0.1 12.8 0.1 2.1 2 0 0 2 2 2 0 RII binding domain MFS_1 PF07690.11 KFM07163.1 - 3.5e-09 35.8 35.0 3.5e-09 35.8 24.2 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily PX PF00787.19 KFM07164.1 - 5e-23 81.0 1.9 9.9e-23 80.0 1.3 1.5 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 KFM07164.1 - 2.5e-12 46.5 0.0 8.4e-09 35.0 0.0 2.4 1 1 0 1 1 1 1 Vps5 C terminal like BAR PF03114.13 KFM07164.1 - 3.2e-08 33.3 0.5 3.2e-08 33.3 0.3 1.7 2 0 0 2 2 2 1 BAR domain BAR_3_WASP_bdg PF10456.4 KFM07164.1 - 0.0046 16.2 0.2 0.013 14.7 0.0 1.7 2 0 0 2 2 2 1 WASP-binding domain of Sorting nexin protein DUF842 PF05811.8 KFM07164.1 - 0.42 10.0 3.9 1.8 8.0 0.5 2.3 1 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) Cache_2 PF08269.6 KFM07165.1 - 0.031 14.2 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 Cache domain DUF3504 PF12012.3 KFM07166.1 - 5.1e-16 58.9 0.2 1.4e-15 57.5 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3504) WIF PF02019.13 KFM07166.1 - 0.04 13.3 0.1 0.51 9.7 0.0 2.2 2 0 0 2 2 2 0 WIF domain SCP2 PF02036.12 KFM07167.1 - 8.1e-21 74.2 0.0 9.3e-21 74.0 0.0 1.0 1 0 0 1 1 1 1 SCP-2 sterol transfer family SCP2 PF02036.12 KFM07168.1 - 1.9e-23 82.6 0.1 4e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family adh_short PF00106.20 KFM07168.1 - 2.6e-17 63.2 0.0 4.1e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFM07168.1 - 1.5e-07 31.4 0.0 2.2e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFM07168.1 - 3.9e-05 23.3 0.2 7.5e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 KR domain Alkyl_sulf_C PF14864.1 KFM07168.1 - 0.0034 17.3 0.0 0.0065 16.4 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Eno-Rase_NADH_b PF12242.3 KFM07168.1 - 1.1 9.0 3.8 0.87 9.4 0.3 2.5 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Hexapep PF00132.19 KFM07169.1 - 1.1e-05 24.7 3.2 1.1e-05 24.7 2.2 2.4 3 0 0 3 3 3 1 Bacterial transferase hexapeptide (six repeats) Yeast-kill-tox PF09207.6 KFM07169.1 - 0.018 15.4 0.8 0.024 15.0 0.6 1.2 1 0 0 1 1 1 0 Yeast killer toxin TFIIE_beta PF02186.10 KFM07170.1 - 1.3e-24 85.9 0.4 3.5e-24 84.5 0.1 1.9 2 0 0 2 2 2 1 TFIIE beta subunit core domain DUF1880 PF08976.6 KFM07170.1 - 0.049 13.7 0.3 0.19 11.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) Myosin_tail_1 PF01576.14 KFM07170.1 - 0.078 10.6 0.1 0.12 10.0 0.1 1.1 1 0 0 1 1 1 0 Myosin tail NusG PF02357.14 KFM07170.1 - 0.11 12.8 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 Transcription termination factor nusG PDZ PF00595.19 KFM07170.1 - 0.11 12.6 0.1 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) Shisa PF13908.1 KFM07171.1 - 0.0053 16.9 0.1 0.0058 16.8 0.1 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Mtp PF03821.11 KFM07171.1 - 0.049 13.0 1.0 0.051 12.9 0.7 1.0 1 0 0 1 1 1 0 Golgi 4-transmembrane spanning transporter DUF3753 PF12575.3 KFM07171.1 - 0.12 12.2 2.8 0.21 11.4 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) DNA_pol_A_exo1 PF01612.15 KFM07172.1 - 5.5e-38 130.1 0.0 1e-37 129.3 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease Helicase_C PF00271.26 KFM07172.1 - 2.6e-18 65.6 0.1 6.6e-18 64.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFM07172.1 - 1.4e-16 60.4 0.0 3.1e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase RQC PF09382.5 KFM07172.1 - 2.4e-15 56.1 0.0 1.2e-14 53.8 0.0 2.3 2 0 0 2 2 2 1 RQC domain HTH_40 PF14493.1 KFM07172.1 - 1.3e-11 44.5 0.0 6e-11 42.4 0.0 2.2 1 0 0 1 1 1 1 Helix-turn-helix domain HRDC PF00570.18 KFM07172.1 - 3.6e-11 42.5 0.1 9e-11 41.3 0.1 1.7 1 0 0 1 1 1 1 HRDC domain ResIII PF04851.10 KFM07172.1 - 0.0027 17.5 0.0 0.012 15.4 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit PAN_3 PF08277.7 KFM07172.1 - 0.39 10.3 5.0 1.4 8.6 0.4 3.5 4 0 0 4 4 4 0 PAN-like domain PurA PF04845.8 KFM07173.1 - 1.7e-106 354.2 0.0 2e-106 354.0 0.0 1.0 1 0 0 1 1 1 1 PurA ssDNA and RNA-binding protein DUF3276 PF11680.3 KFM07173.1 - 1.7e-06 27.8 0.3 0.44 10.3 0.0 3.3 3 0 0 3 3 3 3 Protein of unknown function (DUF3276) Metallophos PF00149.23 KFM07174.1 - 3.5e-42 144.0 0.8 4.5e-42 143.7 0.5 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pyr_redox_dim PF02852.17 KFM07175.1 - 1.2e-34 118.6 0.4 2.4e-34 117.6 0.3 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 KFM07175.1 - 4.1e-27 95.3 0.1 7e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFM07175.1 - 4.3e-19 68.6 0.1 1.1e-18 67.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFM07175.1 - 0.0055 16.7 0.0 0.032 14.3 0.0 1.9 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFM07175.1 - 0.027 13.3 0.0 0.05 12.5 0.0 1.4 1 1 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) zf-H2C2_2 PF13465.1 KFM07176.1 - 6e-45 149.4 41.2 7.5e-09 35.4 1.1 7.1 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.21 KFM07176.1 - 2.6e-35 118.6 51.5 6.4e-06 26.2 1.0 7.1 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KFM07176.1 - 2.2e-21 74.9 35.5 4.3e-05 23.2 3.8 7.1 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KFM07176.1 - 6.6e-21 73.0 40.6 0.0014 18.8 0.7 7.1 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM07176.1 - 1.3e-08 34.7 24.8 0.0039 17.2 0.1 6.6 7 0 0 7 7 6 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM07176.1 - 1.5e-08 34.5 33.4 0.13 12.4 0.0 6.8 7 0 0 7 7 7 3 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 KFM07176.1 - 2.5e-07 30.5 30.2 0.02 14.8 1.9 5.9 3 2 2 5 5 5 3 Zinc ribbon domain LIM PF00412.17 KFM07176.1 - 3e-06 27.2 19.3 0.029 14.4 0.8 4.3 4 1 0 4 4 4 3 LIM domain zf-Di19 PF05605.7 KFM07176.1 - 4e-06 26.8 24.9 0.0055 16.7 0.9 4.7 2 1 2 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding CpXC PF14353.1 KFM07176.1 - 5.1e-06 26.4 19.2 1.3 8.9 0.1 5.9 3 2 1 4 4 4 1 CpXC protein zf-C2HC_2 PF13913.1 KFM07176.1 - 1.1e-05 24.9 24.9 0.26 10.9 1.0 5.7 6 0 0 6 6 5 4 zinc-finger of a C2HC-type Ogr_Delta PF04606.7 KFM07176.1 - 0.00012 21.6 21.5 0.013 15.1 0.2 4.4 3 1 2 5 5 5 3 Ogr/Delta-like zinc finger Zn_Tnp_IS1595 PF12760.2 KFM07176.1 - 0.00024 20.8 31.7 0.013 15.3 1.4 4.6 2 2 2 5 5 5 2 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.1 KFM07176.1 - 0.00072 18.6 23.8 1.4 8.2 0.1 6.2 6 0 0 6 6 6 1 zinc-ribbon domain Sgf11 PF08209.6 KFM07176.1 - 0.00099 18.3 22.1 2.7 7.3 0.0 6.3 6 0 0 6 6 6 1 Sgf11 (transcriptional regulation protein) A2L_zn_ribbon PF08792.5 KFM07176.1 - 0.0018 17.6 20.3 0.82 9.2 0.1 5.7 6 0 0 6 6 6 1 A2L zinc ribbon domain Zn_ribbon_recom PF13408.1 KFM07176.1 - 0.002 18.3 26.6 0.33 11.2 2.2 5.3 2 2 2 4 4 4 2 Recombinase zinc beta ribbon domain XPA_N PF01286.13 KFM07176.1 - 0.0021 17.7 21.6 1 9.0 0.1 6.0 6 0 0 6 6 6 2 XPA protein N-terminal zinc_ribbon_2 PF13240.1 KFM07176.1 - 0.0023 17.3 27.0 0.022 14.2 1.1 6.0 5 2 1 6 6 6 3 zinc-ribbon domain Terminase_GpA PF05876.7 KFM07176.1 - 0.0033 15.8 12.1 0.084 11.2 1.7 2.5 1 1 0 2 2 2 2 Phage terminase large subunit (GpA) zf-met2 PF12907.2 KFM07176.1 - 0.0035 17.2 11.8 2 8.4 0.0 4.6 3 1 1 4 4 4 1 Zinc-binding C1_4 PF07975.7 KFM07176.1 - 0.0048 16.8 25.9 2.5 8.1 3.9 5.7 1 1 3 4 4 4 1 TFIIH C1-like domain FYDLN_acid PF09538.5 KFM07176.1 - 0.0048 17.4 16.5 2.2 8.8 0.1 5.1 2 2 2 4 4 4 1 Protein of unknown function (FYDLN_acid) zf-trcl PF13451.1 KFM07176.1 - 0.0095 15.5 21.9 1.8 8.2 1.6 5.6 4 1 1 5 5 5 1 Probable zinc-binding domain Elf1 PF05129.8 KFM07176.1 - 0.013 15.2 20.7 0.36 10.5 0.7 4.3 1 1 3 4 4 4 0 Transcription elongation factor Elf1 like zinc_ribbon_5 PF13719.1 KFM07176.1 - 0.013 15.0 26.3 3.3 7.3 0.0 6.3 5 1 0 5 5 5 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KFM07176.1 - 0.036 13.7 26.4 5.8 6.7 0.0 6.3 5 1 0 5 5 5 0 zinc-ribbon domain DUF164 PF02591.10 KFM07176.1 - 0.038 13.8 22.5 1.3 8.8 0.9 5.3 4 2 1 5 5 5 0 Putative zinc ribbon domain PhnA_Zn_Ribbon PF08274.7 KFM07176.1 - 0.039 13.7 1.0 0.039 13.7 0.7 5.2 4 2 0 4 4 4 0 PhnA Zinc-Ribbon UPF0547 PF10571.4 KFM07176.1 - 0.046 13.4 22.7 3.7 7.3 0.1 5.8 6 0 0 6 6 6 0 Uncharacterised protein family UPF0547 TFIIS_C PF01096.13 KFM07176.1 - 0.088 12.4 22.0 21 4.8 0.1 6.0 6 0 0 6 6 6 0 Transcription factor S-II (TFIIS) zf-ISL3 PF14690.1 KFM07176.1 - 0.11 12.4 27.9 5.4 7.1 0.2 6.3 5 1 2 7 7 7 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HypA PF01155.14 KFM07176.1 - 0.12 12.1 20.4 0.42 10.3 0.3 3.6 1 1 3 4 4 4 0 Hydrogenase expression/synthesis hypA family zf-AN1 PF01428.11 KFM07176.1 - 0.12 12.2 30.9 7.3 6.5 0.0 6.3 3 2 3 6 6 6 0 AN1-like Zinc finger Gin PF10764.4 KFM07176.1 - 0.12 12.0 11.2 3.4 7.4 0.0 5.0 5 1 1 6 6 5 0 Inhibitor of sigma-G Gin zf-C4_Topoisom PF01396.14 KFM07176.1 - 0.13 11.8 18.8 1.1 8.7 0.1 5.5 6 0 0 6 6 5 0 Topoisomerase DNA binding C4 zinc finger DUF4428 PF14471.1 KFM07176.1 - 0.14 11.9 15.4 0.52 10.0 1.6 4.5 1 1 4 5 5 5 0 Domain of unknown function (DUF4428) DUF329 PF03884.9 KFM07176.1 - 0.15 11.6 20.8 11 5.7 0.1 5.9 6 0 0 6 6 6 0 Domain of unknown function (DUF329) DUF2296 PF10058.4 KFM07176.1 - 0.21 11.3 18.5 21 4.9 0.0 5.2 5 0 0 5 5 5 0 Predicted integral membrane metal-binding protein (DUF2296) TF_Zn_Ribbon PF08271.7 KFM07176.1 - 0.21 10.9 26.4 0.32 10.3 2.4 5.6 4 2 0 4 4 4 0 TFIIB zinc-binding Mut7-C PF01927.11 KFM07176.1 - 0.26 11.2 0.2 0.26 11.2 0.1 3.9 1 1 2 3 3 2 0 Mut7-C RNAse domain Rep_fac-A_C PF08646.5 KFM07176.1 - 0.4 10.3 16.4 0.88 9.2 0.0 4.0 1 1 2 4 4 4 0 Replication factor-A C terminal domain DUF1610 PF07754.6 KFM07176.1 - 0.4 10.8 0.2 0.4 10.8 0.1 6.3 6 0 0 6 6 6 0 Domain of unknown function (DUF1610) zf-RING_3 PF14369.1 KFM07176.1 - 0.45 10.5 25.4 5.8 7.0 0.1 5.6 5 1 1 6 6 6 0 zinc-finger Rubredoxin PF00301.15 KFM07176.1 - 0.47 10.3 15.6 15 5.5 0.0 5.3 6 0 0 6 6 5 0 Rubredoxin YhfH PF14149.1 KFM07176.1 - 0.67 9.7 18.2 15 5.5 0.0 5.1 6 0 0 6 6 4 0 YhfH-like protein zf-HIT PF04438.11 KFM07176.1 - 1.1 8.9 27.5 7.7 6.2 1.2 6.0 6 0 0 6 6 6 0 HIT zinc finger C1_3 PF07649.7 KFM07176.1 - 1.4 9.0 18.0 31 4.7 0.0 5.7 6 0 0 6 6 5 0 C1-like domain zf-RING_5 PF14634.1 KFM07176.1 - 1.5 8.6 25.0 1 9.1 0.4 4.2 3 2 0 3 3 3 0 zinc-RING finger domain zf-IS66 PF13005.2 KFM07176.1 - 2.8 7.9 25.2 9.1 6.3 0.0 5.9 5 1 1 6 6 5 0 zinc-finger binding domain of transposase IS66 IBR PF01485.16 KFM07176.1 - 5.3 7.0 26.9 57 3.6 2.9 4.6 1 1 1 2 2 1 0 IBR domain Yippee-Mis18 PF03226.9 KFM07176.1 - 10 6.2 17.4 27 4.8 3.7 3.6 1 1 2 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-H2C2_2 PF13465.1 KFM07177.1 - 1.7e-87 283.7 103.1 1.3e-08 34.7 1.0 13.0 13 0 0 13 13 13 12 Zinc-finger double domain zf-C2H2 PF00096.21 KFM07177.1 - 1.1e-70 229.9 102.2 5.2e-07 29.6 1.0 12.5 12 1 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM07177.1 - 1.3e-39 131.6 92.0 0.00031 20.8 1.1 12.1 12 0 0 12 12 12 12 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM07177.1 - 1.6e-32 110.3 78.8 5.9e-05 22.8 1.0 12.9 12 1 0 12 12 12 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM07177.1 - 3.1e-18 65.3 53.7 0.073 13.2 0.0 12.4 12 1 0 12 12 12 8 Zinc-finger double-stranded RNA-binding C1_4 PF07975.7 KFM07177.1 - 2.7e-12 46.4 52.2 0.023 14.6 0.9 9.9 1 1 5 9 9 9 7 TFIIH C1-like domain Prok-RING_1 PF14446.1 KFM07177.1 - 2.9e-07 30.0 41.2 1.1 9.0 0.0 11.7 11 1 0 11 11 11 2 Prokaryotic RING finger family 1 RRN7 PF11781.3 KFM07177.1 - 3.5e-06 26.4 49.1 1.8 8.1 0.1 12.0 12 1 0 12 12 12 3 RNA polymerase I-specific transcription initiation factor Rrn7 Zn-ribbon_8 PF09723.5 KFM07177.1 - 8.3e-05 22.4 83.2 0.93 9.4 4.2 11.3 4 3 6 10 10 10 5 Zinc ribbon domain LIM PF00412.17 KFM07177.1 - 0.00047 20.1 61.4 0.57 10.2 2.0 9.3 2 2 5 8 8 8 5 LIM domain zf-met PF12874.2 KFM07177.1 - 0.0049 17.0 61.5 1.7 8.9 1.1 12.0 11 1 0 12 12 12 2 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 KFM07177.1 - 0.012 15.7 3.7 0.012 15.7 2.6 12.3 13 1 0 13 13 13 0 C2H2-type zinc-finger domain zf-UBP PF02148.14 KFM07177.1 - 0.1 12.7 56.0 10 6.2 3.5 7.6 2 1 3 6 6 6 0 Zn-finger in ubiquitin-hydrolases and other protein XPA_N PF01286.13 KFM07177.1 - 0.43 10.2 68.7 1.7 8.3 0.1 12.0 12 0 0 12 12 12 0 XPA protein N-terminal Zn_ribbon_recom PF13408.1 KFM07177.1 - 0.55 10.5 52.4 0.84 9.9 1.2 8.0 5 2 1 7 7 7 0 Recombinase zinc beta ribbon domain zf-ISL3 PF14690.1 KFM07177.1 - 2.2 8.3 60.1 0.19 11.7 0.4 11.6 12 0 0 12 12 12 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 CpXC PF14353.1 KFM07177.1 - 3 7.8 48.2 16 5.4 1.3 10.4 9 2 1 10 10 10 0 CpXC protein HNH_5 PF14279.1 KFM07177.1 - 3.3 7.7 14.9 15 5.6 0.0 6.2 7 1 0 7 7 7 0 HNH endonuclease C1_3 PF07649.7 KFM07177.1 - 5.8 7.0 44.1 3.5 7.7 0.7 10.9 12 0 0 12 12 12 0 C1-like domain DUF309 PF03745.9 KFM07177.1 - 6.1 6.3 10.0 18 4.8 0.1 4.6 5 0 0 5 5 5 0 Domain of unknown function (DUF309) zf-C2H2 PF00096.21 KFM07179.1 - 7.8e-17 60.5 8.6 5.2e-09 35.9 0.7 2.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM07179.1 - 1.6e-15 56.4 11.0 1.4e-08 34.5 0.5 3.0 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_6 PF13912.1 KFM07179.1 - 1.4e-13 50.2 5.0 3.6e-06 26.6 0.5 2.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KFM07179.1 - 2.5e-12 46.1 6.4 4.1e-07 29.8 0.4 2.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM07179.1 - 1.7e-07 31.1 2.6 0.00029 20.8 0.2 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 KFM07179.1 - 6.2e-05 22.8 2.2 0.13 12.2 0.1 2.2 2 0 0 2 2 2 2 Zinc ribbon domain Prok-RING_1 PF14446.1 KFM07179.1 - 0.00019 21.0 0.1 0.25 11.1 0.0 2.1 2 0 0 2 2 2 2 Prokaryotic RING finger family 1 C1_4 PF07975.7 KFM07179.1 - 0.00062 19.7 1.4 0.024 14.6 0.0 2.0 1 1 1 2 2 2 1 TFIIH C1-like domain UPF0547 PF10571.4 KFM07179.1 - 0.00076 19.1 6.3 0.04 13.6 0.2 2.1 2 0 0 2 2 2 2 Uncharacterised protein family UPF0547 Yippee-Mis18 PF03226.9 KFM07179.1 - 0.0011 18.9 0.3 1 9.4 0.0 2.0 2 0 0 2 2 2 2 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly CpXC PF14353.1 KFM07179.1 - 0.0015 18.4 0.5 1.6 8.7 0.0 2.0 2 0 0 2 2 2 2 CpXC protein zf-ribbon_3 PF13248.1 KFM07179.1 - 0.0022 17.1 2.8 0.15 11.3 0.1 2.2 2 0 0 2 2 2 1 zinc-ribbon domain XPA_N PF01286.13 KFM07179.1 - 0.0028 17.3 1.9 0.98 9.1 0.1 2.1 2 0 0 2 2 2 2 XPA protein N-terminal zf-met PF12874.2 KFM07179.1 - 0.0033 17.5 3.3 0.27 11.4 0.2 2.3 1 1 0 2 2 2 1 Zinc-finger of C2H2 type TF_Zn_Ribbon PF08271.7 KFM07179.1 - 0.0037 16.5 0.9 0.36 10.1 0.1 2.2 2 0 0 2 2 2 1 TFIIB zinc-binding DNA_RNApol_7kD PF03604.8 KFM07179.1 - 0.0073 15.7 1.7 1.5 8.3 0.2 2.2 2 0 0 2 2 2 1 DNA directed RNA polymerase, 7 kDa subunit Zn_ribbon_recom PF13408.1 KFM07179.1 - 0.0079 16.4 1.9 1.2 9.4 0.4 2.1 1 1 1 2 2 2 1 Recombinase zinc beta ribbon domain zinc_ribbon_5 PF13719.1 KFM07179.1 - 0.0085 15.6 1.1 0.9 9.1 0.1 2.1 2 0 0 2 2 2 1 zinc-ribbon domain zf-Di19 PF05605.7 KFM07179.1 - 0.0094 16.0 2.1 0.021 14.9 1.4 1.6 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 KFM07179.1 - 0.011 15.4 4.6 0.053 13.1 0.2 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zinc_ribbon_4 PF13717.1 KFM07179.1 - 0.013 15.2 1.3 0.88 9.3 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain YhfH PF14149.1 KFM07179.1 - 0.013 15.2 1.9 3 7.7 0.1 2.2 2 0 0 2 2 2 0 YhfH-like protein zf-ISL3 PF14690.1 KFM07179.1 - 0.017 15.1 6.0 0.6 10.1 0.1 2.4 2 1 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 TFIIS_C PF01096.13 KFM07179.1 - 0.019 14.5 3.0 2.4 7.8 0.2 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) DUF1610 PF07754.6 KFM07179.1 - 0.021 14.9 8.0 0.66 10.1 2.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) zf-HIT PF04438.11 KFM07179.1 - 0.021 14.4 3.5 1.7 8.3 0.2 2.2 2 0 0 2 2 2 0 HIT zinc finger C1_3 PF07649.7 KFM07179.1 - 0.025 14.5 1.1 4.9 7.2 0.0 2.3 2 0 0 2 2 2 0 C1-like domain A2L_zn_ribbon PF08792.5 KFM07179.1 - 0.026 13.9 3.0 1.8 8.1 0.2 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 KFM07179.1 - 0.037 13.8 6.6 0.067 13.0 4.6 1.5 1 1 0 1 1 1 0 Transposase zinc-ribbon domain DZR PF12773.2 KFM07179.1 - 0.038 13.7 2.5 0.073 12.9 1.7 1.5 1 1 0 1 1 1 0 Double zinc ribbon Ribosomal_S27e PF01667.12 KFM07179.1 - 0.043 13.3 0.5 1.8 8.1 0.1 2.1 2 0 0 2 2 2 0 Ribosomal protein S27 FYVE PF01363.16 KFM07179.1 - 0.049 13.5 4.3 0.29 11.0 1.8 2.0 1 1 1 2 2 2 0 FYVE zinc finger SprT-like PF10263.4 KFM07179.1 - 0.057 13.0 1.6 0.069 12.8 1.1 1.1 1 0 0 1 1 1 0 SprT-like family FYDLN_acid PF09538.5 KFM07179.1 - 0.058 13.9 0.3 1.5 9.3 0.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) C1_1 PF00130.17 KFM07179.1 - 0.062 13.0 0.7 0.15 11.7 0.5 1.7 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-BED PF02892.10 KFM07179.1 - 0.076 12.7 3.7 1.9 8.3 0.1 2.2 1 1 1 2 2 2 0 BED zinc finger LIM PF00412.17 KFM07179.1 - 0.077 13.0 1.2 0.24 11.5 0.8 1.7 1 1 0 1 1 1 0 LIM domain Terminase_GpA PF05876.7 KFM07179.1 - 0.09 11.1 1.2 0.088 11.1 0.8 1.0 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) DUF2321 PF10083.4 KFM07179.1 - 0.11 11.9 0.4 0.18 11.2 0.3 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) COX5B PF01215.14 KFM07179.1 - 0.12 12.0 2.6 2.7 7.6 0.2 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase subunit Vb DUF2296 PF10058.4 KFM07179.1 - 0.13 12.0 1.6 6.8 6.5 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Rtf2 PF04641.7 KFM07179.1 - 0.13 11.3 0.2 0.15 11.2 0.1 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger RRN7 PF11781.3 KFM07179.1 - 0.16 11.4 1.0 3.6 7.1 0.1 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Desulfoferrod_N PF06397.7 KFM07179.1 - 0.17 11.2 3.7 6.1 6.3 0.2 2.2 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain zinc-ribbons_6 PF07191.7 KFM07179.1 - 0.2 11.4 1.5 0.27 11.0 1.0 1.3 1 1 0 1 1 1 0 zinc-ribbons DUF2072 PF09845.4 KFM07179.1 - 0.23 11.4 1.8 8.7 6.2 0.1 2.1 2 0 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) zf-RING_3 PF14369.1 KFM07179.1 - 0.28 11.2 2.8 8.5 6.4 0.1 2.2 2 0 0 2 2 2 0 zinc-finger RNA_pol_N PF01194.12 KFM07179.1 - 0.28 11.2 1.2 1.9 8.5 0.1 2.1 1 1 1 2 2 2 0 RNA polymerases N / 8 kDa subunit DUF35_N PF12172.3 KFM07179.1 - 0.34 10.8 4.3 4.5 7.3 0.1 2.5 2 1 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-AN1 PF01428.11 KFM07179.1 - 0.34 10.8 5.9 5.3 7.0 0.7 2.4 2 1 0 2 2 2 0 AN1-like Zinc finger Mut7-C PF01927.11 KFM07179.1 - 0.43 10.5 2.3 3.6 7.5 1.6 2.0 1 1 0 1 1 1 0 Mut7-C RNAse domain zf-UBP PF02148.14 KFM07179.1 - 0.44 10.7 3.4 1.5 9.0 0.1 2.0 1 1 1 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein Evr1_Alr PF04777.8 KFM07179.1 - 0.47 10.4 1.8 1.6 8.6 0.1 1.9 1 1 1 2 2 2 0 Erv1 / Alr family zf-Mss51 PF13824.1 KFM07179.1 - 0.59 10.0 5.6 3.9 7.4 0.4 2.1 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zinc_ribbon_2 PF13240.1 KFM07179.1 - 0.71 9.4 8.6 7.1 6.2 6.0 2.1 1 1 0 1 1 1 0 zinc-ribbon domain Ribosomal_L44 PF00935.14 KFM07179.1 - 0.75 9.8 3.8 14 5.8 0.1 2.3 1 1 1 2 2 2 0 Ribosomal protein L44 Zn_Tnp_IS1 PF03811.8 KFM07179.1 - 0.89 9.1 11.3 0.58 9.6 6.4 1.8 2 1 0 2 2 1 0 InsA N-terminal domain zf-H2C2_5 PF13909.1 KFM07179.1 - 0.96 9.8 13.4 0.23 11.7 1.7 2.9 2 2 0 2 2 2 0 C2H2-type zinc-finger domain zf-trcl PF13451.1 KFM07179.1 - 1.1 8.8 4.0 6.6 6.4 2.8 2.0 1 1 0 1 1 1 0 Probable zinc-binding domain Ogr_Delta PF04606.7 KFM07179.1 - 1.2 8.8 5.3 6.4 6.5 3.7 2.0 1 1 0 1 1 1 0 Ogr/Delta-like zinc finger zf-TFIIB PF13453.1 KFM07179.1 - 1.7 7.9 4.1 3.5 6.8 2.8 1.5 1 1 0 1 1 1 0 Transcription factor zinc-finger OrfB_Zn_ribbon PF07282.6 KFM07179.1 - 1.9 8.1 4.8 7.5 6.2 3.2 1.9 1 1 0 1 1 1 0 Putative transposase DNA-binding domain Tnp_zf-ribbon_2 PF13842.1 KFM07179.1 - 2.3 8.6 5.2 40 4.7 3.6 2.1 1 1 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon zf-H2C2_2 PF13465.1 KFM07181.1 - 4.6e-98 317.0 108.3 3.4e-09 36.5 0.9 13.5 13 1 1 14 14 14 13 Zinc-finger double domain zf-C2H2 PF00096.21 KFM07181.1 - 5.6e-81 262.2 104.6 6.2e-08 32.5 0.2 12.2 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM07181.1 - 2.6e-45 149.4 92.7 0.00019 21.5 2.0 12.1 12 0 0 12 12 12 12 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM07181.1 - 7.8e-43 143.1 85.9 2.5e-05 23.9 0.9 12.5 13 0 0 13 13 13 11 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM07181.1 - 7.4e-18 64.1 55.4 0.04 14.0 0.1 11.9 12 0 0 12 12 12 8 Zinc-finger double-stranded RNA-binding C1_4 PF07975.7 KFM07181.1 - 4.7e-12 45.7 56.3 0.029 14.3 1.2 11.0 1 1 8 10 10 10 7 TFIIH C1-like domain Prok-RING_1 PF14446.1 KFM07181.1 - 1.5e-06 27.8 45.6 0.15 11.8 0.9 11.4 8 4 2 10 10 10 2 Prokaryotic RING finger family 1 Zn-ribbon_8 PF09723.5 KFM07181.1 - 3.7e-06 26.7 88.4 0.015 15.2 3.9 11.3 6 4 5 11 11 10 4 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 KFM07181.1 - 0.00011 21.9 78.0 0.042 13.6 3.4 9.6 8 2 1 9 9 9 5 Transposase zinc-ribbon domain zf-H2C2_5 PF13909.1 KFM07181.1 - 0.00013 21.9 1.2 0.00013 21.9 0.8 13.2 12 4 0 12 12 12 1 C2H2-type zinc-finger domain CpXC PF14353.1 KFM07181.1 - 0.00015 21.7 48.3 1.6 8.6 0.0 10.9 8 3 0 9 9 9 3 CpXC protein Zn_ribbon_recom PF13408.1 KFM07181.1 - 0.00047 20.3 54.8 0.33 11.2 2.1 8.6 5 3 2 7 7 7 4 Recombinase zinc beta ribbon domain RRN7 PF11781.3 KFM07181.1 - 0.00075 18.9 44.3 1.7 8.2 0.1 11.6 12 0 0 12 12 12 2 RNA polymerase I-specific transcription initiation factor Rrn7 DUF2213 PF09979.4 KFM07181.1 - 0.031 13.9 0.1 1.7 8.3 0.0 3.1 2 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2213) XPA_N PF01286.13 KFM07181.1 - 0.043 13.5 61.5 0.77 9.4 0.3 11.5 12 0 0 12 12 12 0 XPA protein N-terminal C1_3 PF07649.7 KFM07181.1 - 0.15 12.1 48.4 2 8.4 0.1 11.6 12 0 0 12 12 12 0 C1-like domain LIM PF00412.17 KFM07181.1 - 0.59 10.2 55.7 0.89 9.6 1.5 8.9 2 2 7 10 10 10 0 LIM domain zf-met PF12874.2 KFM07181.1 - 0.94 9.7 68.8 0.93 9.7 0.1 11.8 12 0 0 12 12 12 0 Zinc-finger of C2H2 type DUF309 PF03745.9 KFM07181.1 - 1.6 8.2 4.5 6.5 6.2 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF309) HCV_core PF01542.13 KFM07182.1 - 0.03 14.7 0.7 1.2 9.6 0.0 2.8 2 1 1 3 3 3 0 Hepatitis C virus core protein KRAB PF01352.22 KFM07183.1 - 4.7e-22 77.1 1.0 5.3e-22 76.9 0.7 1.0 1 0 0 1 1 1 1 KRAB box PRY PF13765.1 KFM07184.1 - 2.3e-21 75.0 0.3 3.3e-21 74.5 0.2 1.2 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.23 KFM07184.1 - 2.1e-19 69.8 0.0 2.9e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 SPRY domain PRY PF13765.1 KFM07185.1 - 5.7e-22 76.9 0.2 8.7e-22 76.4 0.2 1.3 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.23 KFM07185.1 - 1.1e-15 57.8 0.0 1.8e-15 57.0 0.0 1.3 2 0 0 2 2 2 1 SPRY domain WD40 PF00400.27 KFM07186.1 - 2.2e-44 147.8 18.3 3.9e-12 45.5 0.1 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 KFM07186.1 - 2.3e-06 27.4 0.2 0.00037 20.2 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Env-gp36 PF09590.5 KFM07186.1 - 0.051 11.7 0.2 0.066 11.4 0.1 1.1 1 0 0 1 1 1 0 Lentivirus surface glycoprotein Nup160 PF11715.3 KFM07186.1 - 0.44 8.6 6.5 1.7 6.6 1.2 3.4 1 1 2 3 3 3 0 Nucleoporin Nup120/160 PRY PF13765.1 KFM07187.1 - 8.6e-25 86.0 0.8 3.6e-24 84.0 0.3 2.0 2 0 0 2 2 2 1 SPRY-associated domain SPRY PF00622.23 KFM07187.1 - 4.5e-23 81.6 0.1 5.2e-23 81.4 0.1 1.1 1 0 0 1 1 1 1 SPRY domain zf-C3HC4_4 PF15227.1 KFM07188.1 - 9.8e-16 57.3 10.7 9.8e-16 57.3 7.4 2.2 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-B_box PF00643.19 KFM07188.1 - 1.6e-10 40.7 1.8 1.6e-10 40.7 1.2 3.6 4 0 0 4 4 4 1 B-box zinc finger zf-C3HC4 PF00097.20 KFM07188.1 - 2.9e-10 39.6 10.0 2.9e-10 39.6 6.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM07188.1 - 4e-10 39.5 11.6 4e-10 39.5 8.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFM07188.1 - 5e-10 38.9 5.4 5e-10 38.9 3.7 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.1 KFM07188.1 - 5.6e-09 35.6 10.3 5.6e-09 35.6 7.1 2.4 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFM07188.1 - 2.9e-07 30.0 8.9 2.9e-07 30.0 6.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM07188.1 - 1.1e-06 28.2 10.3 1.1e-06 28.2 7.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.1 KFM07188.1 - 1.2e-05 24.9 4.1 2.7e-05 23.8 2.9 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Nse PF11789.3 KFM07188.1 - 0.00024 20.5 4.6 0.00048 19.5 3.2 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 KFM07188.1 - 0.0044 16.9 0.0 0.0079 16.1 0.0 1.4 1 0 0 1 1 1 1 U-box domain RDM PF11002.3 KFM07188.1 - 0.039 13.6 0.0 0.054 13.1 0.0 1.2 1 0 0 1 1 1 0 RFPL defining motif (RDM) IBR PF01485.16 KFM07188.1 - 1.9 8.4 18.7 0.6 10.0 3.0 3.0 1 1 1 2 2 2 0 IBR domain zf-rbx1 PF12678.2 KFM07188.1 - 2.5 8.2 13.6 1.2 9.3 5.3 2.7 2 1 0 2 2 2 0 RING-H2 zinc finger zf-RING_4 PF14570.1 KFM07188.1 - 2.7 7.6 20.5 0.18 11.3 8.6 2.9 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain DZR PF12773.2 KFM07188.1 - 3.3 7.5 19.0 8.1 6.3 0.4 2.9 2 1 1 3 3 3 0 Double zinc ribbon zf-Apc11 PF12861.2 KFM07188.1 - 4 7.3 9.2 0.61 9.9 3.2 2.0 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger PRY PF13765.1 KFM07189.1 - 1.3e-25 88.6 0.5 2.3e-25 87.8 0.4 1.4 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.23 KFM07189.1 - 1.5e-18 67.0 0.4 1.9e-18 66.7 0.3 1.1 1 0 0 1 1 1 1 SPRY domain zf-C3HC4_4 PF15227.1 KFM07190.1 - 1.9e-12 46.8 4.4 2.2e-12 46.6 3.0 1.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 KFM07190.1 - 4.3e-09 36.2 5.0 4.7e-09 36.1 3.5 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM07190.1 - 5.3e-09 35.5 4.7 5.9e-09 35.4 3.3 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM07190.1 - 3.1e-07 30.0 4.3 3.3e-07 30.0 3.0 1.1 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KFM07190.1 - 1.5e-06 27.8 5.0 1.7e-06 27.6 3.4 1.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFM07190.1 - 4e-06 26.3 3.0 4.5e-06 26.2 2.0 1.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFM07190.1 - 7.8e-06 25.5 3.5 8.5e-06 25.3 2.4 1.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 KFM07190.1 - 0.001 18.8 1.4 0.001 18.7 1.0 1.0 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Nse PF11789.3 KFM07190.1 - 0.027 14.0 0.9 0.029 13.9 0.6 1.1 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 KFM07190.1 - 0.22 11.6 6.5 1.5 9.0 4.5 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger FYVE PF01363.16 KFM07190.1 - 0.23 11.3 4.8 0.63 9.9 3.3 1.7 1 1 0 1 1 1 0 FYVE zinc finger IBR PF01485.16 KFM07190.1 - 2 8.3 5.5 7.9 6.4 3.8 1.8 1 1 0 1 1 1 0 IBR domain zf-C3HC4_4 PF15227.1 KFM07191.1 - 1.4e-14 53.6 12.4 1.4e-14 53.6 8.6 2.1 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-B_box PF00643.19 KFM07191.1 - 9.2e-12 44.6 2.1 9.2e-12 44.6 1.5 3.5 3 1 0 3 3 3 1 B-box zinc finger zf-C3HC4 PF00097.20 KFM07191.1 - 1.2e-09 37.6 12.1 1.2e-09 37.6 8.4 1.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM07191.1 - 5.3e-08 32.7 13.5 5.3e-08 32.7 9.3 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM07191.1 - 2.8e-07 30.0 9.8 2.8e-07 30.0 6.8 2.4 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM07191.1 - 9.2e-07 28.5 13.3 9.2e-07 28.5 9.2 2.3 2 1 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 KFM07191.1 - 3.4e-06 26.6 6.4 3.4e-06 26.6 4.5 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 KFM07191.1 - 0.00014 21.5 12.6 0.00014 21.5 8.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.1 KFM07191.1 - 0.0023 17.6 4.0 0.0049 16.6 2.7 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Baculo_IE-1 PF05290.6 KFM07191.1 - 0.0037 16.9 7.1 0.0048 16.6 2.8 2.1 2 0 0 2 2 2 1 Baculovirus immediate-early protein (IE-0) Fer2_4 PF13510.1 KFM07191.1 - 0.04 13.7 2.0 0.045 13.5 0.0 2.0 2 1 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain U-box PF04564.10 KFM07191.1 - 0.082 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 U-box domain zf-Nse PF11789.3 KFM07191.1 - 0.1 12.1 6.2 0.19 11.2 4.3 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 KFM07191.1 - 0.6 9.7 17.9 0.053 13.0 8.1 2.4 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 KFM07191.1 - 0.63 9.9 12.0 0.38 10.6 5.3 2.5 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.2 KFM07191.1 - 1.1 9.0 16.5 4.7 7.1 6.5 2.7 2 1 1 3 3 3 0 Double zinc ribbon zf-rbx1 PF12678.2 KFM07191.1 - 6.9 6.8 20.5 15 5.7 1.2 2.7 2 1 0 2 2 2 0 RING-H2 zinc finger PRY PF13765.1 KFM07192.1 - 1.7e-24 85.0 0.3 2.6e-24 84.4 0.2 1.3 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.23 KFM07192.1 - 1.4e-17 63.9 0.0 2.2e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 SPRY domain Opiods_neuropep PF01160.13 KFM07192.1 - 0.061 13.0 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Vertebrate endogenous opioids neuropeptide PRY PF13765.1 KFM07193.1 - 3.4e-27 93.7 0.1 5.6e-27 93.0 0.1 1.4 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.23 KFM07193.1 - 4.1e-19 68.8 0.0 5e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 SPRY domain SPRY PF00622.23 KFM07194.1 - 8.7e-18 64.6 0.1 1.6e-17 63.7 0.0 1.5 2 0 0 2 2 2 1 SPRY domain PRY PF13765.1 KFM07194.1 - 2e-13 49.6 0.0 3.9e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 SPRY-associated domain PRY PF13765.1 KFM07195.1 - 1.8e-26 91.3 0.6 2.7e-26 90.8 0.4 1.3 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.23 KFM07195.1 - 5.8e-19 68.3 0.0 7.5e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 SPRY domain Activin_recp PF01064.18 KFM07196.1 - 0.01 16.4 10.4 0.013 16.0 7.2 1.2 1 0 0 1 1 1 0 Activin types I and II receptor domain UPAR_LY6 PF00021.16 KFM07196.1 - 0.1 13.0 11.0 0.16 12.3 7.7 1.5 1 1 0 1 1 1 0 u-PAR/Ly-6 domain Toxin_1 PF00087.16 KFM07196.1 - 7.7 6.9 11.6 43 4.5 8.0 2.1 1 1 0 1 1 1 0 Snake toxin SPRY PF00622.23 KFM07197.1 - 8.3e-25 87.2 0.5 9.8e-25 87.0 0.3 1.1 1 0 0 1 1 1 1 SPRY domain PRY PF13765.1 KFM07197.1 - 2.4e-19 68.5 0.3 2.8e-18 65.1 0.1 2.1 2 0 0 2 2 2 1 SPRY-associated domain Amino_oxidase PF01593.19 KFM07198.1 - 1.4e-76 258.4 0.0 1.6e-76 258.2 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KFM07198.1 - 7.3e-17 61.1 0.1 1.7e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFM07198.1 - 5.4e-08 32.1 0.3 1.8e-06 27.1 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFM07198.1 - 3.6e-06 27.2 0.1 1.3e-05 25.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KFM07198.1 - 5.9e-06 25.9 0.1 1.7e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 KFM07198.1 - 6.9e-06 26.2 0.0 8.5e-05 22.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFM07198.1 - 1.7e-05 24.0 0.1 3e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 KFM07198.1 - 2.7e-05 23.2 0.1 5.5e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KFM07198.1 - 0.0001 20.9 0.6 0.00023 19.7 0.2 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 KFM07198.1 - 0.00011 21.3 0.3 0.00019 20.6 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KFM07198.1 - 0.00062 19.6 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KFM07198.1 - 0.0026 16.9 0.0 0.0036 16.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KFM07198.1 - 0.021 14.4 0.1 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 KFM07198.1 - 0.026 13.1 0.5 0.044 12.4 0.3 1.3 1 0 0 1 1 1 0 Tryptophan halogenase NAD_Gly3P_dh_N PF01210.18 KFM07198.1 - 0.037 13.7 0.1 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 KFM07198.1 - 0.04 13.3 0.8 0.18 11.2 0.1 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 KFM07198.1 - 0.054 12.3 0.0 0.096 11.5 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A FMO-like PF00743.14 KFM07198.1 - 0.077 11.1 0.0 0.14 10.3 0.0 1.3 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Lycopene_cycl PF05834.7 KFM07198.1 - 0.084 11.7 0.0 1.7 7.4 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein TrkA_N PF02254.13 KFM07198.1 - 0.091 12.7 0.1 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.1 KFM07198.1 - 0.11 12.2 0.1 0.24 11.1 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding zf-H2C2_2 PF13465.1 KFM07199.1 - 2.8e-55 181.9 44.0 5.7e-11 42.1 0.9 6.8 7 0 0 7 7 6 6 Zinc-finger double domain zf-C2H2 PF00096.21 KFM07199.1 - 2.1e-43 144.0 47.5 5.5e-08 32.6 0.9 7.1 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KFM07199.1 - 4.4e-26 89.9 27.3 0.00013 21.7 0.1 7.1 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KFM07199.1 - 1.4e-25 87.6 41.9 2.8e-05 24.1 0.5 7.1 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM07199.1 - 4.3e-12 45.7 7.2 0.0048 17.0 0.1 6.3 6 0 0 6 6 6 1 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 KFM07199.1 - 2e-10 40.4 19.5 0.0087 15.9 1.4 6.0 4 2 0 4 4 4 2 Zinc ribbon domain zf-CHY PF05495.7 KFM07199.1 - 5.1e-07 29.7 12.4 0.0034 17.4 1.9 3.2 1 1 2 3 3 3 3 CHY zinc finger C1_4 PF07975.7 KFM07199.1 - 9.8e-07 28.6 12.7 0.018 15.0 0.5 5.1 1 1 5 6 6 6 1 TFIIH C1-like domain DNA_RNApol_7kD PF03604.8 KFM07199.1 - 1.5e-05 24.3 17.1 1.9 7.9 0.1 6.3 6 0 0 6 6 6 1 DNA directed RNA polymerase, 7 kDa subunit XPA_N PF01286.13 KFM07199.1 - 1.5e-05 24.5 16.3 0.31 10.7 0.1 5.9 6 0 0 6 6 6 1 XPA protein N-terminal zf-Di19 PF05605.7 KFM07199.1 - 2.1e-05 24.5 18.4 0.0016 18.5 0.5 4.4 2 2 2 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding DZR PF12773.2 KFM07199.1 - 2.8e-05 23.8 15.5 0.51 10.2 3.8 3.7 1 1 1 2 2 2 1 Double zinc ribbon Elf1 PF05129.8 KFM07199.1 - 3.3e-05 23.5 11.6 0.1 12.3 0.1 4.0 1 1 4 5 5 5 4 Transcription elongation factor Elf1 like zf-met PF12874.2 KFM07199.1 - 3.9e-05 23.6 23.7 0.02 15.0 0.2 6.6 7 0 0 7 7 6 1 Zinc-finger of C2H2 type FYDLN_acid PF09538.5 KFM07199.1 - 3.9e-05 24.1 8.6 4.5 7.8 0.1 5.6 1 1 4 5 5 5 0 Protein of unknown function (FYDLN_acid) zinc_ribbon_5 PF13719.1 KFM07199.1 - 5.6e-05 22.6 17.5 1.9 8.1 0.0 6.0 5 1 1 6 6 6 2 zinc-ribbon domain Zn_ribbon_recom PF13408.1 KFM07199.1 - 5.7e-05 23.2 24.1 1.5 9.1 3.2 5.7 3 2 2 5 5 5 1 Recombinase zinc beta ribbon domain SprT-like PF10263.4 KFM07199.1 - 7.1e-05 22.5 15.4 0.0092 15.6 2.6 3.2 1 1 1 2 2 2 1 SprT-like family CpXC PF14353.1 KFM07199.1 - 0.0002 21.3 11.5 2.8 7.9 0.1 5.7 6 0 0 6 6 6 1 CpXC protein HypA PF01155.14 KFM07199.1 - 0.00041 20.0 12.9 0.25 11.0 0.4 3.4 1 1 1 3 3 3 2 Hydrogenase expression/synthesis hypA family zinc_ribbon_4 PF13717.1 KFM07199.1 - 0.00062 19.4 16.6 3.9 7.2 0.6 6.0 5 1 1 6 6 6 0 zinc-ribbon domain zf-trcl PF13451.1 KFM07199.1 - 0.00095 18.7 17.3 9.7 5.9 0.0 6.0 6 0 0 6 6 6 0 Probable zinc-binding domain Prok-RING_1 PF14446.1 KFM07199.1 - 0.001 18.7 9.7 3.4 7.4 0.0 5.8 6 0 0 6 6 6 0 Prokaryotic RING finger family 1 GAGA PF09237.6 KFM07199.1 - 0.0034 16.9 4.6 0.3 10.7 0.2 3.3 2 1 1 3 3 3 1 GAGA factor zf-ISL3 PF14690.1 KFM07199.1 - 0.0057 16.6 24.8 1.1 9.3 0.2 6.4 6 0 0 6 6 6 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 RRN7 PF11781.3 KFM07199.1 - 0.0069 15.8 14.9 2.9 7.4 0.1 5.5 6 0 0 6 6 6 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-AN1 PF01428.11 KFM07199.1 - 0.0081 16.0 24.5 5.6 6.9 0.1 6.4 5 1 1 6 6 6 0 AN1-like Zinc finger BolA PF01722.13 KFM07199.1 - 0.011 15.6 3.7 0.04 13.8 0.1 2.9 2 2 0 2 2 2 0 BolA-like protein ADK_lid PF05191.9 KFM07199.1 - 0.015 14.9 25.9 0.38 10.4 0.2 6.3 5 1 0 5 5 5 0 Adenylate kinase, active site lid zf-CSL PF05207.8 KFM07199.1 - 0.022 14.2 1.6 0.022 14.2 1.1 3.9 2 2 1 3 3 3 0 CSL zinc finger DUF164 PF02591.10 KFM07199.1 - 0.032 14.0 15.6 0.28 11.0 0.3 4.4 3 2 2 5 5 5 0 Putative zinc ribbon domain TFIIS_C PF01096.13 KFM07199.1 - 0.033 13.8 16.6 4.2 7.0 0.1 5.9 6 0 0 6 6 6 0 Transcription factor S-II (TFIIS) zinc_ribbon_2 PF13240.1 KFM07199.1 - 0.047 13.1 23.5 1.5 8.4 0.2 5.4 4 2 0 4 4 4 0 zinc-ribbon domain LIM PF00412.17 KFM07199.1 - 0.061 13.4 14.3 12 6.0 0.5 4.9 1 1 4 5 5 5 0 LIM domain zf-ribbon_3 PF13248.1 KFM07199.1 - 0.091 12.0 23.2 0.81 8.9 0.2 6.0 6 0 0 6 6 6 0 zinc-ribbon domain zf-DNA_Pol PF08996.5 KFM07199.1 - 0.14 11.4 9.0 3.5 6.9 0.2 3.1 1 1 2 3 3 3 0 DNA Polymerase alpha zinc finger zf-LYAR PF08790.6 KFM07199.1 - 0.21 11.2 16.4 2.2 8.0 0.1 5.4 6 0 0 6 6 5 0 LYAR-type C2HC zinc finger COX5B PF01215.14 KFM07199.1 - 0.21 11.2 15.4 6.6 6.4 0.1 5.1 1 1 5 6 6 5 0 Cytochrome c oxidase subunit Vb zf-RING_5 PF14634.1 KFM07199.1 - 0.32 10.7 14.3 13 5.6 2.4 4.4 1 1 3 4 4 4 0 zinc-RING finger domain Zn_Tnp_IS1595 PF12760.2 KFM07199.1 - 0.38 10.6 34.6 1.8 8.4 2.6 4.9 2 1 4 6 6 6 0 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 KFM07199.1 - 0.73 9.3 23.6 5.2 6.6 0.1 5.9 6 0 0 6 6 6 0 A2L zinc ribbon domain C1_3 PF07649.7 KFM07199.1 - 0.77 9.8 16.6 12 6.0 0.0 5.8 6 0 0 6 6 6 0 C1-like domain Ribosomal_L37ae PF01780.14 KFM07199.1 - 0.86 9.5 11.2 1.5 8.7 0.1 4.1 1 1 0 3 3 3 0 Ribosomal L37ae protein family DUF329 PF03884.9 KFM07199.1 - 1.4 8.5 12.0 7.6 6.1 0.1 5.0 6 0 0 6 6 6 0 Domain of unknown function (DUF329) zf-Mss51 PF13824.1 KFM07199.1 - 2 8.3 24.9 2.4 8.1 0.3 5.3 2 2 1 3 3 2 0 Zinc-finger of mitochondrial splicing suppressor 51 FdhE PF04216.7 KFM07199.1 - 2 8.0 13.4 8.9 5.9 5.3 3.0 1 1 1 2 2 2 0 Protein involved in formate dehydrogenase formation zf-RING_3 PF14369.1 KFM07199.1 - 4.2 7.4 22.3 4.4 7.3 0.1 5.3 5 1 1 6 6 6 0 zinc-finger zf-HIT PF04438.11 KFM07199.1 - 5 6.8 25.5 1.4 8.6 0.3 5.7 6 0 0 6 6 6 0 HIT zinc finger DUF2688 PF10892.3 KFM07199.1 - 5.3 6.7 16.4 7.2 6.3 0.0 5.0 4 2 0 4 4 4 0 Protein of unknown function (DUF2688) CoiA PF06054.6 KFM07199.1 - 5.8 5.7 6.2 13 4.5 0.2 3.0 3 0 0 3 3 3 0 Competence protein CoiA-like family Evr1_Alr PF04777.8 KFM07199.1 - 8.8 6.3 14.2 19 5.2 0.1 4.7 1 1 3 4 4 4 0 Erv1 / Alr family FYVE PF01363.16 KFM07199.1 - 9 6.2 28.4 8.1 6.4 0.6 4.8 1 1 2 3 3 3 0 FYVE zinc finger HCV_core PF01542.13 KFM07200.1 - 0.26 11.6 8.2 2.2 8.7 0.5 3.2 1 1 3 4 4 4 0 Hepatitis C virus core protein MtrC PF04211.8 KFM07200.1 - 0.99 8.3 9.5 1.2 8.1 6.6 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit C zf-H2C2_2 PF13465.1 KFM07201.1 - 2.1e-60 198.1 69.4 1.2e-10 41.1 0.7 9.9 10 0 0 10 10 10 9 Zinc-finger double domain zf-C2H2 PF00096.21 KFM07201.1 - 1.4e-49 163.5 62.6 1.1e-06 28.6 1.1 9.2 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM07201.1 - 3.6e-24 83.2 66.5 0.0025 18.0 1.0 9.1 9 0 0 9 9 9 8 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM07201.1 - 4.8e-20 70.7 61.0 0.0001 22.0 0.6 10.1 9 4 0 9 9 9 8 C2H2-type zinc finger XPA_N PF01286.13 KFM07201.1 - 2.3e-08 33.5 28.3 1.2 8.9 0.0 8.9 9 0 0 9 9 9 3 XPA protein N-terminal zf-trcl PF13451.1 KFM07201.1 - 1.9e-06 27.4 39.2 0.081 12.5 2.2 8.7 7 2 0 7 7 7 2 Probable zinc-binding domain Zn-ribbon_8 PF09723.5 KFM07201.1 - 7.9e-05 22.5 49.2 0.23 11.4 4.4 8.5 4 3 2 6 6 6 2 Zinc ribbon domain zf-LYAR PF08790.6 KFM07201.1 - 0.0025 17.4 19.5 20 5.0 0.0 8.5 9 0 0 9 9 9 0 LYAR-type C2HC zinc finger C1_4 PF07975.7 KFM07201.1 - 0.017 15.1 30.1 0.19 11.7 1.4 7.0 2 2 3 6 6 6 0 TFIIH C1-like domain GAGA PF09237.6 KFM07201.1 - 0.02 14.4 7.3 0.41 10.2 1.4 3.1 2 1 0 2 2 2 0 GAGA factor zf-RING_3 PF14369.1 KFM07201.1 - 0.033 14.1 37.7 3.4 7.7 0.2 8.5 9 0 0 9 9 9 0 zinc-finger FYVE PF01363.16 KFM07201.1 - 0.078 12.8 45.8 0.11 12.4 7.4 6.2 1 1 2 3 3 2 0 FYVE zinc finger Zn_Tnp_IS1595 PF12760.2 KFM07201.1 - 0.083 12.7 53.0 0.2 11.4 3.9 6.8 6 1 0 6 6 6 0 Transposase zinc-ribbon domain Mut7-C PF01927.11 KFM07201.1 - 0.17 11.8 33.0 3.8 7.4 1.6 7.0 1 1 4 5 5 5 0 Mut7-C RNAse domain TFIIS_C PF01096.13 KFM07201.1 - 0.38 10.4 36.5 0.62 9.7 0.8 8.4 8 1 0 8 8 8 0 Transcription factor S-II (TFIIS) DNA_RNApol_7kD PF03604.8 KFM07201.1 - 0.66 9.5 39.7 3.2 7.2 0.4 8.8 9 0 0 9 9 9 0 DNA directed RNA polymerase, 7 kDa subunit zf-C2H2_jaz PF12171.3 KFM07201.1 - 0.88 9.7 30.0 4.9 7.4 0.2 8.3 9 0 0 9 9 9 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_5 PF13719.1 KFM07201.1 - 1.9 8.1 37.7 1.1 8.9 0.1 8.7 9 0 0 9 9 9 0 zinc-ribbon domain FYDLN_acid PF09538.5 KFM07201.1 - 2.4 8.7 19.6 11 6.7 0.3 6.3 2 2 3 5 5 5 0 Protein of unknown function (FYDLN_acid) LIM PF00412.17 KFM07201.1 - 3.1 7.9 28.5 1.4 9.0 0.8 6.3 2 2 5 7 7 7 0 LIM domain Zn_ribbon_recom PF13408.1 KFM07201.1 - 4.2 7.6 43.7 36 4.7 2.9 7.6 2 2 5 7 7 7 0 Recombinase zinc beta ribbon domain CpXC PF14353.1 KFM07201.1 - 5.2 7.0 26.9 30 4.5 0.1 8.1 7 2 2 9 9 9 0 CpXC protein HypA PF01155.14 KFM07201.1 - 6.4 6.5 33.2 1.3 8.6 0.4 5.4 2 1 4 6 6 6 0 Hydrogenase expression/synthesis hypA family RRN7 PF11781.3 KFM07201.1 - 7.3 6.1 32.6 1.8 8.1 0.1 8.2 9 0 0 9 9 9 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-H2C2_2 PF13465.1 KFM07202.1 - 9.3e-86 278.2 78.4 7.1e-09 35.5 0.6 12.5 13 0 0 13 13 12 11 Zinc-finger double domain zf-C2H2 PF00096.21 KFM07202.1 - 3e-75 244.2 84.3 1.3e-06 28.3 0.4 12.1 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM07202.1 - 6.1e-40 132.6 81.8 0.00099 19.2 0.1 12.1 12 0 0 12 12 12 12 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM07202.1 - 5.7e-28 95.9 52.9 0.00058 19.6 0.1 12.8 12 0 0 12 12 12 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM07202.1 - 2e-20 72.3 25.8 0.011 15.8 0.0 11.9 12 0 0 12 12 12 5 Zinc-finger double-stranded RNA-binding Elf1 PF05129.8 KFM07202.1 - 4e-07 29.6 19.5 0.064 12.9 0.0 6.9 1 1 6 7 7 7 3 Transcription elongation factor Elf1 like BolA PF01722.13 KFM07202.1 - 7.5e-07 29.0 4.6 0.38 10.7 0.0 5.4 4 2 1 5 5 5 1 BolA-like protein Zn-ribbon_8 PF09723.5 KFM07202.1 - 2.4e-05 24.1 61.6 0.21 11.5 2.0 10.7 6 6 3 9 9 9 4 Zinc ribbon domain C1_4 PF07975.7 KFM07202.1 - 0.00017 21.5 30.4 2.8 8.0 0.1 8.7 1 1 9 10 10 10 2 TFIIH C1-like domain zf-C2HC_2 PF13913.1 KFM07202.1 - 0.0011 18.5 0.3 0.0011 18.5 0.2 11.5 12 0 0 12 12 11 2 zinc-finger of a C2HC-type XPA_N PF01286.13 KFM07202.1 - 0.0035 16.9 41.3 9.1 6.0 0.0 11.5 12 0 0 12 12 12 0 XPA protein N-terminal DUF2256 PF10013.4 KFM07202.1 - 0.006 16.3 44.0 0.37 10.5 0.0 10.6 10 2 2 12 12 12 3 Uncharacterized protein conserved in bacteria (DUF2256) DUF164 PF02591.10 KFM07202.1 - 0.064 13.0 34.6 4.8 7.0 0.8 8.7 8 1 1 9 9 9 0 Putative zinc ribbon domain HypA PF01155.14 KFM07202.1 - 0.075 12.7 34.4 1.1 9.0 0.8 6.4 1 1 2 4 4 4 0 Hydrogenase expression/synthesis hypA family FYDLN_acid PF09538.5 KFM07202.1 - 0.098 13.2 23.0 37 4.9 0.7 8.8 3 2 7 10 10 9 0 Protein of unknown function (FYDLN_acid) zf-Di19 PF05605.7 KFM07202.1 - 0.098 12.7 0.4 0.098 12.7 0.3 7.6 3 2 7 10 10 10 0 Drought induced 19 protein (Di19), zinc-binding zf-trcl PF13451.1 KFM07202.1 - 0.11 12.1 47.1 0.35 10.5 0.0 11.0 11 1 0 11 11 11 0 Probable zinc-binding domain zf-RING_3 PF14369.1 KFM07202.1 - 2.6 8.1 47.7 0.39 10.7 0.3 9.4 9 1 1 10 10 10 0 zinc-finger zinc_ribbon_5 PF13719.1 KFM07202.1 - 2.7 7.6 0.0 2.7 7.6 0.0 10.8 10 2 0 10 10 10 0 zinc-ribbon domain COX5B PF01215.14 KFM07202.1 - 8.1 6.1 24.7 34 4.1 0.0 7.9 4 2 4 8 8 8 0 Cytochrome c oxidase subunit Vb SPRY PF00622.23 KFM07203.1 - 3.3e-27 95.0 0.3 4.3e-27 94.6 0.2 1.2 1 0 0 1 1 1 1 SPRY domain PRY PF13765.1 KFM07203.1 - 5.2e-22 77.1 0.1 8.5e-22 76.4 0.1 1.4 1 0 0 1 1 1 1 SPRY-associated domain zf-C2H2 PF00096.21 KFM07204.1 - 1.4e-18 66.0 36.9 0.00023 21.3 0.3 5.5 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM07204.1 - 2.1e-13 49.8 30.8 1.2e-05 25.3 0.3 5.4 4 1 1 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM07204.1 - 3.6e-10 39.4 29.3 0.055 13.8 1.1 5.5 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_7 PF15269.1 KFM07204.1 - 0.031 14.1 0.2 0.031 14.1 0.1 2.7 2 1 0 2 2 2 0 Zinc-finger YL1 PF05764.8 KFM07204.1 - 0.14 11.7 9.6 0.26 10.8 6.7 1.3 1 0 0 1 1 1 0 YL1 nuclear protein zf-C2H2_jaz PF12171.3 KFM07204.1 - 0.51 10.5 21.0 0.55 10.4 0.1 4.6 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 KFM07204.1 - 2 8.4 19.9 0.23 11.4 0.2 4.6 4 1 0 4 4 4 0 Zinc ribbon domain zf-met PF12874.2 KFM07204.1 - 2 8.7 22.6 6.1 7.2 0.1 5.3 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Lectin_C PF00059.16 KFM07205.1 - 5.5e-05 23.7 0.2 9.1e-05 23.0 0.1 1.4 1 1 0 1 1 1 1 Lectin C-type domain EGF PF00008.22 KFM07206.1 - 0.00018 21.4 3.3 0.00042 20.2 2.3 1.7 1 0 0 1 1 1 1 EGF-like domain Laminin_EGF PF00053.19 KFM07206.1 - 0.021 14.7 3.2 0.06 13.2 2.2 1.7 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) hEGF PF12661.2 KFM07206.1 - 0.032 14.3 2.0 0.08 13.0 1.4 1.7 1 0 0 1 1 1 0 Human growth factor-like EGF cEGF PF12662.2 KFM07206.1 - 0.25 10.9 3.0 0.79 9.4 2.1 1.8 1 0 0 1 1 1 0 Complement Clr-like EGF-like EGF_2 PF07974.8 KFM07206.1 - 0.6 10.3 6.5 1.5 9.0 4.5 1.8 1 0 0 1 1 1 0 EGF-like domain SH2 PF00017.19 KFM07208.1 - 2.5e-16 59.2 0.1 7.4e-16 57.7 0.0 1.9 1 0 0 1 1 1 1 SH2 domain Arm PF00514.18 KFM07209.1 - 4.4e-21 73.8 19.6 8.9e-07 28.5 0.1 8.1 8 0 0 8 8 8 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFM07209.1 - 4.6e-14 52.4 11.8 0.0011 19.1 0.0 6.2 3 2 3 6 6 6 5 HEAT repeats Proteasom_PSMB PF10508.4 KFM07209.1 - 3.1e-06 25.7 9.1 0.00013 20.3 0.2 3.5 2 2 2 4 4 4 2 Proteasome non-ATPase 26S subunit V-ATPase_H_C PF11698.3 KFM07209.1 - 2.1e-05 24.4 7.5 0.00011 22.1 0.1 4.0 4 1 0 4 4 4 1 V-ATPase subunit H HEAT_EZ PF13513.1 KFM07209.1 - 2.3e-05 24.7 3.3 1.3 9.6 0.0 5.5 5 0 0 5 5 5 1 HEAT-like repeat HEAT PF02985.17 KFM07209.1 - 4.5e-05 23.1 5.2 1.3 9.3 0.0 5.7 7 0 0 7 7 5 2 HEAT repeat V-ATPase_H_N PF03224.9 KFM07209.1 - 4.6e-05 22.6 14.5 0.092 11.8 0.8 5.0 2 2 3 5 5 5 3 V-ATPase subunit H PUL PF08324.6 KFM07209.1 - 0.0043 15.8 1.8 0.34 9.6 0.1 3.3 3 1 0 4 4 4 1 PUL domain MarR_2 PF12802.2 KFM07209.1 - 0.031 13.9 0.0 0.14 11.8 0.0 2.2 1 0 0 1 1 1 0 MarR family Vps39_1 PF10366.4 KFM07209.1 - 0.032 14.2 0.7 0.032 14.2 0.5 2.9 2 1 1 3 3 3 0 Vacuolar sorting protein 39 domain 1 DRIM PF07539.7 KFM07209.1 - 0.099 12.0 6.5 6.3 6.2 0.0 4.1 4 0 0 4 4 4 0 Down-regulated in metastasis RTTN_N PF14726.1 KFM07209.1 - 0.15 12.6 11.6 1.1 9.8 0.0 4.5 4 2 0 5 5 5 0 Rotatin, an armadillo repeat protein, centriole functioning dsDNA_bind PF01984.15 KFM07209.1 - 0.28 11.1 0.1 0.28 11.1 0.0 4.1 4 2 0 4 4 4 0 Double-stranded DNA-binding domain Tetraspannin PF00335.15 KFM07210.1 - 2.1e-44 151.4 12.2 2.6e-44 151.1 8.5 1.1 1 0 0 1 1 1 1 Tetraspanin family Sensor PF13796.1 KFM07210.1 - 0.2 11.2 13.0 0.57 9.7 5.4 2.4 3 0 0 3 3 3 0 Putative sensor UPF0444 PF15475.1 KFM07211.1 - 0.048 13.7 0.1 0.072 13.1 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein C12orf23, UPF0444 Dpy-30 PF05186.8 KFM07213.1 - 3.6e-14 51.9 0.1 4.1e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Dpy-30 motif S-AdoMet_synt_C PF02773.11 KFM07214.1 - 7.3e-78 258.9 0.3 1.2e-77 258.3 0.2 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 KFM07214.1 - 2.6e-48 162.8 0.0 4.8e-48 162.0 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 KFM07214.1 - 6e-43 145.1 0.1 1.3e-42 144.0 0.1 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Lectin_C PF00059.16 KFM07216.1 - 9.3e-17 61.5 0.2 1.1e-16 61.3 0.1 1.1 1 0 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.16 KFM07217.1 - 3.8e-19 69.2 0.6 4.3e-19 69.0 0.4 1.0 1 0 0 1 1 1 1 Lectin C-type domain RasGEF PF00617.14 KFM07218.1 - 7.6e-47 159.4 2.1 7.6e-47 159.4 1.4 1.9 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 KFM07218.1 - 0.0059 16.6 0.0 0.028 14.5 0.0 2.2 2 0 0 2 2 2 1 RasGEF N-terminal motif Taeniidae_ag PF05596.6 KFM07218.1 - 0.044 13.6 1.8 4.8 7.0 0.1 3.6 3 1 0 3 3 3 0 Taeniidae antigen CHGN PF05679.11 KFM07219.1 - 1.7e-60 205.1 0.0 2.2e-60 204.7 0.0 1.1 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.9 KFM07219.1 - 2.4e-09 36.5 0.2 6.6e-09 35.1 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFM07219.1 - 7.3e-07 28.5 0.0 2.6e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 KfrA_N PF11740.3 KFM07219.1 - 0.004 17.6 0.2 0.0072 16.7 0.2 1.3 1 0 0 1 1 1 1 Plasmid replication region DNA-binding N-term FadA PF09403.5 KFM07219.1 - 0.046 13.7 2.5 0.1 12.6 1.7 1.5 1 0 0 1 1 1 0 Adhesion protein FadA Prefoldin PF02996.12 KFM07219.1 - 0.076 12.6 2.8 0.26 10.9 1.9 1.9 1 0 0 1 1 1 0 Prefoldin subunit DUF342 PF03961.8 KFM07219.1 - 0.084 11.2 2.6 0.13 10.6 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4407 PF14362.1 KFM07219.1 - 0.094 11.6 0.8 0.17 10.8 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Allexi_40kDa PF05549.6 KFM07219.1 - 0.1 11.9 0.3 0.17 11.1 0.2 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein Striatin PF08232.7 KFM07219.1 - 0.2 12.0 5.4 0.37 11.1 3.7 1.3 1 0 0 1 1 1 0 Striatin family IncA PF04156.9 KFM07219.1 - 0.21 11.1 4.7 0.34 10.4 3.2 1.2 1 0 0 1 1 1 0 IncA protein Fib_alpha PF08702.5 KFM07219.1 - 0.59 10.2 5.6 0.37 10.9 2.6 1.5 2 0 0 2 2 1 0 Fibrinogen alpha/beta chain family Spc24 PF08286.6 KFM07219.1 - 3.3 7.4 7.6 0.68 9.6 2.6 1.8 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Pkinase_Tyr PF07714.12 KFM07220.1 - 1.2e-103 345.6 0.0 1.7e-103 345.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM07220.1 - 1e-47 162.5 0.0 1.9e-47 161.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Cadherin PF00028.12 KFM07220.1 - 1.3e-17 63.7 0.2 1.1e-08 35.2 0.0 4.7 4 1 0 4 4 4 2 Cadherin domain Cadherin_2 PF08266.7 KFM07220.1 - 0.011 15.3 0.3 2.1 7.9 0.0 2.9 3 0 0 3 3 3 0 Cadherin-like RIO1 PF01163.17 KFM07220.1 - 0.026 13.8 0.0 0.16 11.3 0.0 2.0 2 0 0 2 2 2 0 RIO1 family DUF663 PF04950.7 KFM07221.1 - 6.4e-89 297.8 0.0 6.4e-89 297.8 0.0 3.3 3 0 0 3 3 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KFM07221.1 - 1.9e-28 97.8 0.0 6.7e-28 96.0 0.0 2.1 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 KFM07221.1 - 1.5e-07 31.0 0.1 9.8e-05 21.8 0.0 3.0 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain MobB PF03205.9 KFM07221.1 - 0.00017 21.3 2.9 0.00025 20.7 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KFM07221.1 - 0.0016 18.4 0.2 0.011 15.7 0.1 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KFM07221.1 - 0.0025 17.8 0.0 0.007 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 KFM07221.1 - 0.0067 16.6 0.1 0.02 15.1 0.1 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 KFM07221.1 - 0.018 15.5 1.3 0.062 13.8 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_25 PF13481.1 KFM07221.1 - 0.022 14.1 0.0 0.061 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KFM07221.1 - 0.023 14.8 0.2 0.19 11.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.1 KFM07221.1 - 0.042 13.9 0.0 0.14 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 KFM07221.1 - 0.33 9.6 3.2 0.95 8.1 0.0 2.5 2 0 0 2 2 2 0 ArgK protein UQ_con PF00179.21 KFM07222.1 - 5.2e-11 42.1 0.0 6.9e-10 38.4 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFM07222.1 - 0.0032 17.2 0.0 0.0067 16.1 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KFM07222.1 - 0.095 12.5 0.0 15 5.5 0.0 2.3 2 0 0 2 2 2 0 RWD domain RNA_pol_Rpb2_4 PF04566.8 KFM07222.1 - 0.11 12.3 0.0 0.33 10.7 0.0 1.8 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 4 KIAA1430 PF13879.1 KFM07222.1 - 0.43 11.0 5.8 2.5 8.5 0.2 2.6 3 0 0 3 3 3 0 KIAA1430 homologue FIST_C PF10442.4 KFM07223.1 - 9.4e-11 41.7 0.1 1.6e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 FIST C domain Toprim_3 PF13362.1 KFM07223.1 - 0.036 14.3 0.0 0.082 13.1 0.0 1.5 1 0 0 1 1 1 0 Toprim domain PBP_GOBP PF01395.17 KFM07223.1 - 0.036 13.6 0.2 0.093 12.3 0.0 1.7 2 0 0 2 2 2 0 PBP/GOBP family IncA PF04156.9 KFM07225.1 - 0.026 14.1 0.2 0.033 13.7 0.1 1.1 1 0 0 1 1 1 0 IncA protein EGF PF00008.22 KFM07225.1 - 0.033 14.1 2.1 0.033 14.1 1.4 1.9 2 1 0 2 2 2 0 EGF-like domain Laminin_EGF PF00053.19 KFM07225.1 - 0.063 13.2 0.7 0.063 13.2 0.5 1.9 2 0 0 2 2 2 0 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 KFM07225.1 - 0.064 13.4 3.9 0.064 13.4 2.7 2.5 2 1 0 2 2 2 0 EGF-like domain Ion_trans PF00520.26 KFM07226.1 - 8.9e-05 21.8 3.1 8.9e-05 21.8 2.1 1.5 2 0 0 2 2 2 1 Ion transport protein Fib_alpha PF08702.5 KFM07226.1 - 0.43 10.6 3.1 0.46 10.5 1.1 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family ETF_alpha PF00766.14 KFM07227.1 - 3.6e-39 132.2 1.1 5e-39 131.8 0.2 1.7 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.16 KFM07227.1 - 4.8e-36 123.9 0.2 7.6e-36 123.3 0.1 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain zf-met PF12874.2 KFM07228.1 - 6.8e-07 29.2 1.6 2.5e-06 27.4 1.1 2.1 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFM07228.1 - 0.039 14.1 0.5 0.039 14.1 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding EF-hand_7 PF13499.1 KFM07229.1 - 3e-20 72.0 11.3 1.7e-08 34.4 0.3 3.5 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 KFM07229.1 - 6.3e-18 62.6 13.3 9.6e-06 24.5 0.1 5.4 5 1 1 6 6 6 4 EF hand EF-hand_6 PF13405.1 KFM07229.1 - 1.8e-13 49.1 8.5 0.0018 17.9 0.1 4.8 4 1 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 KFM07229.1 - 6.6e-13 47.3 9.4 0.0023 17.1 0.2 4.7 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 KFM07229.1 - 3.2e-06 26.6 14.3 0.018 14.6 0.1 4.8 4 1 1 5 5 5 3 EF-hand domain pair CCDC32 PF14989.1 KFM07229.1 - 0.013 15.3 0.7 0.024 14.4 0.0 1.8 2 0 0 2 2 2 0 Coiled-coil domain containing 32 FCH PF00611.18 KFM07230.1 - 2.8e-17 62.6 0.6 2.8e-17 62.6 0.4 3.0 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 KFM07230.1 - 1e-16 60.2 0.4 2.2e-16 59.1 0.3 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM07230.1 - 1.1e-16 59.9 0.2 2.1e-16 59.0 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFM07230.1 - 1.9e-12 46.4 0.1 3.7e-12 45.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 KFM07230.1 - 0.0042 17.2 0.5 0.0077 16.3 0.4 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain DUF1359 PF07097.6 KFM07230.1 - 0.28 11.2 4.0 1.8 8.6 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1359) TPR_MLP1_2 PF07926.7 KFM07230.1 - 0.72 9.6 31.7 0.21 11.3 0.3 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Neur_chan_memb PF02932.11 KFM07230.1 - 1.2 8.9 9.0 2.2 8.0 6.2 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1657 PF07870.6 KFM07230.1 - 2.8 7.7 10.0 4.7 6.9 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1657) Tetraspannin PF00335.15 KFM07231.1 - 4e-47 160.3 12.4 4.5e-47 160.1 8.6 1.0 1 0 0 1 1 1 1 Tetraspanin family Claudin_2 PF13903.1 KFM07231.1 - 0.00076 19.2 6.5 0.034 13.8 0.4 2.6 2 1 1 3 3 3 2 PMP-22/EMP/MP20/Claudin tight junction SUR7 PF06687.7 KFM07231.1 - 0.007 15.9 6.0 0.085 12.4 1.5 2.2 2 0 0 2 2 2 2 SUR7/PalI family DUF3481 PF11980.3 KFM07231.1 - 0.012 15.4 7.4 0.4 10.5 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3481) NfeD PF01957.13 KFM07231.1 - 0.018 15.1 1.5 0.037 14.1 0.2 1.9 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding Hum_adeno_E3A PF05393.6 KFM07231.1 - 0.058 13.0 2.5 0.33 10.6 0.2 2.3 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein EIID-AGA PF03613.9 KFM07231.1 - 0.93 8.3 4.5 0.16 10.8 0.5 1.6 2 0 0 2 2 2 0 PTS system mannose/fructose/sorbose family IID component DUF872 PF05915.7 KFM07231.1 - 1.9 8.3 6.7 1.9 8.3 2.5 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) FtsX PF02687.16 KFM07231.1 - 4 7.2 12.7 0.17 11.6 0.7 2.9 2 1 1 3 3 3 0 FtsX-like permease family Pkinase PF00069.20 KFM07233.1 - 2.9e-13 49.5 0.0 9.3e-13 47.9 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM07233.1 - 8.5e-07 28.3 0.0 1.8e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFM07233.1 - 0.013 15.2 0.1 0.027 14.2 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family HMG_box PF00505.14 KFM07234.1 - 2.7e-18 65.9 1.2 2.7e-18 65.9 0.8 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFM07234.1 - 3.7e-13 49.6 3.5 6.7e-13 48.8 0.4 2.5 1 1 1 2 2 2 1 HMG-box domain Trans_reg_C PF00486.23 KFM07234.1 - 0.0037 17.1 0.6 1.8 8.5 0.0 3.2 2 1 1 3 3 3 1 Transcriptional regulatory protein, C terminal COG5 PF10392.4 KFM07234.1 - 0.044 13.7 3.7 0.054 13.4 1.5 1.9 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Vac_Fusion PF02346.11 KFM07234.1 - 0.97 8.9 4.2 7.7 6.0 0.1 3.1 2 1 1 3 3 3 0 Chordopoxvirus fusion protein LRR_8 PF13855.1 KFM07235.1 - 4.9e-52 173.5 56.8 1.4e-12 47.1 2.3 6.3 2 1 5 7 7 7 7 Leucine rich repeat LRR_5 PF13306.1 KFM07235.1 - 2.7e-27 95.0 0.5 1e-11 44.6 0.0 3.1 1 1 2 3 3 3 3 Leucine rich repeats (6 copies) LRR_4 PF12799.2 KFM07235.1 - 1.1e-24 85.5 34.7 8.3e-06 25.3 0.3 7.1 6 1 1 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM07235.1 - 1.2e-16 58.2 38.4 0.35 11.0 0.2 12.5 14 0 0 14 14 12 6 Leucine Rich Repeat I-set PF07679.11 KFM07235.1 - 4.9e-14 51.9 0.0 8.6e-14 51.1 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_7 PF13504.1 KFM07235.1 - 4.3e-08 32.0 38.7 2 8.9 0.3 11.6 12 0 0 12 12 12 4 Leucine rich repeat Ig_2 PF13895.1 KFM07235.1 - 2e-06 27.7 0.0 4.3e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFM07235.1 - 5.5e-06 26.7 0.0 1.7e-05 25.2 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFM07235.1 - 0.0011 18.8 0.0 0.0034 17.2 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin V-set domain LRRNT PF01462.13 KFM07235.1 - 0.048 13.1 7.7 0.042 13.3 1.8 3.1 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain LRR_6 PF13516.1 KFM07235.1 - 0.055 13.5 42.0 1.9 8.8 0.1 10.7 12 0 0 12 12 11 0 Leucine Rich repeat LRR_9 PF14580.1 KFM07235.1 - 2.7 7.4 13.0 0.6 9.6 2.2 3.3 1 1 3 4 4 4 0 Leucine-rich repeat BAR_3_WASP_bdg PF10456.4 KFM07237.1 - 4.4e-110 366.5 4.7 5.7e-110 366.2 3.2 1.1 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein PX PF00787.19 KFM07237.1 - 3.7e-20 71.8 3.9 8.4e-20 70.6 0.9 2.3 2 0 0 2 2 2 1 PX domain SH3_9 PF14604.1 KFM07237.1 - 1e-11 44.2 0.0 2.6e-11 42.9 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM07237.1 - 4e-10 38.9 0.0 1e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFM07237.1 - 2.9e-09 36.2 0.0 8.7e-09 34.7 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain Vps5 PF09325.5 KFM07237.1 - 1.9e-05 24.0 3.0 0.0011 18.2 0.8 2.8 1 1 1 2 2 2 1 Vps5 C terminal like BAR PF03114.13 KFM07237.1 - 0.005 16.3 1.4 0.064 12.7 0.5 2.1 2 0 0 2 2 2 1 BAR domain XFP PF03894.10 KFM07237.1 - 0.036 13.6 0.0 0.089 12.3 0.0 1.6 1 0 0 1 1 1 0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase DUF3295 PF11702.3 KFM07237.1 - 0.063 12.2 1.5 2.7 6.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3295) DUF2236 PF09995.4 KFM07237.1 - 0.13 11.4 0.1 0.23 10.7 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2236) mRNA_cap_enzyme PF01331.14 KFM07238.1 - 1.4e-05 24.8 0.0 2.1e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain Y_phosphatase PF00102.22 KFM07239.1 - 1.5e-81 273.1 0.0 2.2e-81 272.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CRAL_TRIO PF00650.15 KFM07239.1 - 1.2e-30 106.0 0.1 2.8e-30 104.9 0.0 1.6 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 KFM07239.1 - 5.5e-12 45.8 0.3 1.4e-11 44.4 0.0 1.8 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KFM07239.1 - 4.1e-05 23.6 0.1 0.00034 20.7 0.0 2.4 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain DSPc PF00782.15 KFM07239.1 - 0.0029 17.1 0.5 0.011 15.2 0.1 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFM07239.1 - 0.0035 17.5 0.0 0.0063 16.7 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KFM07239.1 - 0.077 13.0 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate PAH PF02671.16 KFM07240.1 - 5.2e-55 182.8 2.5 1.5e-20 72.4 0.1 3.7 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 KFM07240.1 - 2.6e-43 145.8 0.3 7.7e-43 144.3 0.2 1.9 1 0 0 1 1 1 1 Sin3 family co-repressor Glyco_hydro_38 PF01074.17 KFM07241.1 - 4.1e-90 301.7 0.1 6.6e-90 301.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 KFM07241.1 - 6.7e-67 226.2 0.0 1.2e-66 225.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 KFM07241.1 - 2.1e-28 98.3 0.1 1.1e-26 92.8 0.0 2.4 2 0 0 2 2 2 1 Alpha mannosidase, middle domain MHCassoc_trimer PF08831.5 KFM07241.1 - 1.5 8.7 4.8 4.5 7.1 3.3 1.8 1 0 0 1 1 1 0 Class II MHC-associated invariant chain trimerisation domain Neil1-DNA_bind PF09292.5 KFM07242.1 - 3e-27 94.1 0.5 5.7e-27 93.2 0.3 1.5 1 0 0 1 1 1 1 Endonuclease VIII-like 1, DNA bind H2TH PF06831.9 KFM07242.1 - 1e-09 37.9 0.0 1.5e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain HCaRG PF07258.9 KFM07243.1 - 2.2e-51 173.9 1.7 2.4e-51 173.7 1.2 1.0 1 0 0 1 1 1 1 HCaRG protein Zona_pellucida PF00100.18 KFM07244.1 - 3.9e-49 167.4 0.0 4.5e-49 167.2 0.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Zona_pellucida PF00100.18 KFM07245.1 - 5.8e-49 166.9 0.2 6.6e-49 166.7 0.1 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain DUF3583 PF12126.3 KFM07246.1 - 3.6e-21 75.5 16.2 6e-21 74.8 11.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3583) zf-B_box PF00643.19 KFM07246.1 - 2.4e-06 27.3 26.9 1.1e-05 25.1 5.9 4.2 4 2 0 4 4 4 2 B-box zinc finger zf-RING_5 PF14634.1 KFM07246.1 - 0.00015 21.3 8.2 0.00015 21.3 5.7 3.8 3 1 0 3 3 3 2 zinc-RING finger domain HAUS6_N PF14661.1 KFM07246.1 - 1 8.6 8.3 0.79 9.0 4.5 1.8 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF393 PF04134.7 KFM07246.1 - 6.2 7.9 0.0 6.2 7.9 0.0 3.8 3 1 0 3 3 3 0 Protein of unknown function, DUF393 Band_7 PF01145.20 KFM07247.1 - 6.1e-16 58.8 0.0 1.1e-15 57.9 0.0 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family SCP2 PF02036.12 KFM07247.1 - 8.5e-16 58.1 0.0 4e-15 55.9 0.0 2.1 2 0 0 2 2 2 1 SCP-2 sterol transfer family DHQS PF01959.11 KFM07247.1 - 0.028 13.1 0.1 0.041 12.5 0.0 1.1 1 0 0 1 1 1 0 3-dehydroquinate synthase (EC 4.6.1.3) zf-RING_5 PF14634.1 KFM07248.1 - 7.6e-06 25.5 7.9 7.6e-06 25.5 5.5 3.4 3 0 0 3 3 3 2 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFM07248.1 - 1.4e-05 24.6 6.3 1.4e-05 24.6 4.4 3.3 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.19 KFM07248.1 - 1.6e-05 24.6 4.9 1.6e-05 24.6 3.4 4.6 4 2 1 5 5 5 2 B-box zinc finger zf-C3HC4_2 PF13923.1 KFM07248.1 - 3.4 7.7 34.6 0.067 13.2 6.3 3.6 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) LRR_8 PF13855.1 KFM07249.1 - 2.6e-20 71.9 7.3 1.2e-10 40.9 0.6 2.2 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 KFM07249.1 - 5.4e-13 48.2 12.9 3.3e-06 26.5 0.0 3.3 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM07249.1 - 5.3e-09 34.8 6.9 0.031 14.2 0.1 5.2 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 KFM07249.1 - 2.1e-06 26.9 6.6 0.18 12.1 0.0 5.2 5 0 0 5 5 5 2 Leucine rich repeat LRR_5 PF13306.1 KFM07249.1 - 7e-06 25.7 0.2 1.2e-05 25.0 0.2 1.4 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_9 PF14580.1 KFM07249.1 - 1.3e-05 24.8 0.2 0.0039 16.7 0.0 1.9 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.1 KFM07249.1 - 0.00032 20.4 12.2 0.43 10.8 0.2 4.7 4 2 1 5 5 5 3 Leucine Rich repeat NosD PF05048.8 KFM07249.1 - 0.046 12.8 0.0 0.059 12.5 0.0 1.1 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) Baculo_PEP_N PF04512.7 KFM07249.1 - 0.064 13.2 0.2 0.17 11.8 0.1 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, N terminus DUF4508 PF14969.1 KFM07249.1 - 0.11 12.5 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) LRR_8 PF13855.1 KFM07250.1 - 2e-22 78.6 11.1 1.4e-12 47.1 2.9 2.1 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 KFM07250.1 - 4.4e-16 58.0 7.4 2.5e-06 26.9 0.0 3.2 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM07250.1 - 1.1e-09 36.9 6.7 0.038 14.0 0.1 4.8 4 1 1 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 KFM07250.1 - 1e-06 27.9 9.7 0.091 13.0 0.0 5.1 5 0 0 5 5 5 2 Leucine rich repeat LRR_9 PF14580.1 KFM07250.1 - 4.6e-05 23.0 0.3 0.0001 21.9 0.2 1.5 1 1 0 1 1 1 1 Leucine-rich repeat LRR_5 PF13306.1 KFM07250.1 - 0.00016 21.4 0.0 0.00021 20.9 0.0 1.2 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_6 PF13516.1 KFM07250.1 - 0.00061 19.5 12.1 0.15 12.2 0.2 5.1 4 1 1 5 5 5 1 Leucine Rich repeat RBP_receptor PF14752.1 KFM07251.1 - 9.3e-242 803.7 23.0 1e-241 803.6 16.0 1.0 1 0 0 1 1 1 1 Retinol binding protein receptor PKD PF00801.15 KFM07252.1 - 0.066 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 PKD domain p450 PF00067.17 KFM07253.1 - 9.4e-24 83.7 0.1 1e-23 83.6 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sema PF01403.14 KFM07254.1 - 6e-26 90.9 0.0 6.6e-26 90.8 0.0 1.0 1 0 0 1 1 1 1 Sema domain ubiquitin PF00240.18 KFM07255.1 - 3.2e-08 32.8 0.0 6.6e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 KFM07255.1 - 9.7e-07 28.4 0.1 2.8e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.3 KFM07255.1 - 0.00087 18.9 0.0 0.0023 17.5 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_4 PF14555.1 KFM07255.1 - 0.013 15.0 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain Ubiquitin_2 PF14560.1 KFM07255.1 - 0.14 12.4 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain Actin PF00022.14 KFM07256.1 - 9.7e-159 527.9 0.0 1.1e-158 527.8 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 KFM07256.1 - 0.1 13.0 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) ARID PF01388.16 KFM07258.1 - 1.7e-27 95.0 0.0 2.9e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain DUF1451 PF07295.6 KFM07258.1 - 0.027 14.2 0.3 0.044 13.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) Pkinase PF00069.20 KFM07259.1 - 6.7e-59 199.1 0.2 9.2e-59 198.7 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM07259.1 - 2.8e-23 82.3 0.2 1.1e-21 77.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase YjeF_N PF03853.10 KFM07260.1 - 8e-18 64.6 0.0 1.2e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 KFM07260.1 - 5.3e-13 49.4 0.0 1e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 FDF domain LSM14 PF12701.2 KFM07260.1 - 2e-12 46.7 0.0 7.8e-12 44.8 0.0 2.0 2 0 0 2 2 2 1 Scd6-like Sm domain Synaphin PF05835.7 KFM07261.1 - 1.2e-32 112.9 11.6 1.5e-32 112.6 8.0 1.1 1 0 0 1 1 1 1 Synaphin protein YdfA_immunity PF12127.3 KFM07261.1 - 0.062 12.1 0.6 0.074 11.9 0.4 1.1 1 0 0 1 1 1 0 SigmaW regulon antibacterial SCAMP PF04144.8 KFM07262.1 - 3.3e-76 255.1 15.2 4e-76 254.8 10.5 1.1 1 0 0 1 1 1 1 SCAMP family DUF3552 PF12072.3 KFM07262.1 - 0.016 14.4 0.3 0.029 13.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Ribosomal_60s PF00428.14 KFM07262.1 - 4 7.9 6.5 5.9 7.3 1.2 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein PMI_typeI PF01238.16 KFM07263.1 - 2.2e-112 375.7 0.0 2.7e-112 375.4 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_6 PF12852.2 KFM07263.1 - 0.026 14.1 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 Cupin COX5A PF02284.11 KFM07264.1 - 5e-57 190.5 0.0 5.6e-57 190.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Alba PF01918.16 KFM07265.1 - 2e-16 59.3 1.1 2.6e-16 58.9 0.8 1.2 1 0 0 1 1 1 1 Alba STAT2_C PF12188.3 KFM07265.1 - 0.089 12.5 0.1 0.36 10.6 0.1 1.9 2 0 0 2 2 2 0 Signal transducer and activator of transcription 2 C terminal SCAMP PF04144.8 KFM07266.1 - 5.7e-74 247.8 12.0 6.7e-74 247.5 8.3 1.0 1 0 0 1 1 1 1 SCAMP family Flavoprotein PF02441.14 KFM07267.1 - 2.3e-46 156.6 0.0 2.8e-46 156.3 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein DUF512 PF04459.7 KFM07267.1 - 0.14 11.1 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF512) SEA PF01390.15 KFM07269.1 - 0.0024 17.5 0.0 0.003 17.2 0.0 1.1 1 0 0 1 1 1 1 SEA domain Lysyl_oxidase PF01186.12 KFM07270.1 - 1e-118 394.3 7.0 1.1e-118 394.1 4.8 1.0 1 0 0 1 1 1 1 Lysyl oxidase CARDB PF07705.6 KFM07270.1 - 0.0021 18.1 0.0 0.029 14.4 0.0 2.3 2 0 0 2 2 2 1 CARDB DUF4589 PF15252.1 KFM07271.1 - 5.3e-85 284.7 0.6 3.4e-84 282.0 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4589) CENP-Q PF13094.1 KFM07271.1 - 0.038 13.9 0.3 0.055 13.4 0.2 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF334 PF03904.8 KFM07271.1 - 0.056 12.7 0.1 0.082 12.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Zona_pellucida PF00100.18 KFM07272.1 - 1.4e-52 178.7 0.0 1.6e-52 178.5 0.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain C1-set PF07654.10 KFM07273.1 - 4.7e-10 39.3 0.1 2.2e-09 37.2 0.1 2.1 3 0 0 3 3 3 1 Immunoglobulin C1-set domain Ig_2 PF13895.1 KFM07273.1 - 7.5e-10 38.8 0.1 0.00013 22.0 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 KFM07273.1 - 1.2e-08 34.6 0.0 0.00079 19.2 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.1 KFM07273.1 - 4e-08 33.6 0.7 0.00019 21.8 0.1 2.8 2 1 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.7 KFM07273.1 - 9.9e-07 28.5 0.1 3e-06 27.0 0.1 1.8 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain V-set PF07686.12 KFM07273.1 - 3.6e-06 26.8 0.0 3.3e-05 23.7 0.0 2.4 2 1 0 2 2 2 1 Immunoglobulin V-set domain ig PF00047.20 KFM07273.1 - 6.3e-06 26.2 0.1 0.061 13.4 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain Marek_A PF02124.10 KFM07273.1 - 0.0029 17.1 0.5 0.0044 16.5 0.3 1.3 1 0 0 1 1 1 1 Marek's disease glycoprotein A I-set PF07679.11 KFM07274.1 - 3.1e-16 59.0 0.1 4.2e-12 45.7 0.1 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM07274.1 - 4e-12 46.0 0.4 7.5e-06 25.9 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 KFM07274.1 - 2.3e-05 24.7 3.8 0.021 15.3 0.2 2.5 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.12 KFM07274.1 - 2.5e-05 24.1 1.4 0.095 12.6 0.2 3.1 2 2 0 2 2 2 2 Immunoglobulin V-set domain ig PF00047.20 KFM07274.1 - 0.0029 17.6 1.7 0.048 13.7 0.0 2.6 2 1 0 2 2 2 1 Immunoglobulin domain REC114-like PF15165.1 KFM07275.1 - 8.2e-96 320.4 0.1 9.8e-96 320.1 0.1 1.1 1 0 0 1 1 1 1 Meiotic recombination protein REC114-like DUF1092 PF06485.6 KFM07275.1 - 0.014 14.4 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1092) Ion_trans_N PF08412.5 KFM07276.1 - 1.5e-44 149.2 0.1 1.5e-44 149.2 0.1 1.9 2 0 0 2 2 2 1 Ion transport protein N-terminal cNMP_binding PF00027.24 KFM07276.1 - 1.1e-20 73.2 0.0 2.2e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.26 KFM07276.1 - 7.1e-19 67.8 10.3 1.3e-18 67.0 7.2 1.4 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.11 KFM07276.1 - 0.0036 16.9 0.2 0.0081 15.8 0.1 1.6 1 0 0 1 1 1 1 Ion channel Neogenin_C PF06583.7 KFM07277.1 - 1.5e-118 396.0 25.5 2.4e-118 395.3 17.7 1.3 1 0 0 1 1 1 1 Neogenin C-terminus fn3 PF00041.16 KFM07277.1 - 1.2e-84 278.4 30.0 4.8e-18 65.0 0.1 6.4 6 0 0 6 6 6 6 Fibronectin type III domain I-set PF07679.11 KFM07277.1 - 6.7e-56 186.1 0.1 2.4e-16 59.3 0.0 6.7 7 0 0 7 7 7 4 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM07277.1 - 7.5e-35 118.9 0.0 5.5e-09 36.0 0.0 5.4 5 0 0 5 5 5 4 Immunoglobulin domain Ig_3 PF13927.1 KFM07277.1 - 5.9e-25 87.5 6.8 3.3e-07 30.7 0.0 7.1 7 1 0 7 7 6 4 Immunoglobulin domain ig PF00047.20 KFM07277.1 - 6.1e-22 77.5 2.0 6.5e-06 26.1 0.0 6.3 5 1 0 5 5 5 3 Immunoglobulin domain V-set PF07686.12 KFM07277.1 - 1.7e-18 66.5 0.5 5e-07 29.6 0.0 7.1 6 2 0 6 6 6 3 Immunoglobulin V-set domain Interfer-bind PF09294.5 KFM07277.1 - 3.9e-15 55.7 0.3 0.043 13.8 0.0 5.9 6 0 0 6 6 6 4 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.12 KFM07277.1 - 4.9e-07 29.4 3.4 0.0082 15.8 0.0 5.1 4 1 1 5 5 5 2 Tissue factor C2-set_2 PF08205.7 KFM07277.1 - 1.2e-06 28.3 0.0 0.41 10.5 0.0 4.1 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain EphA2_TM PF14575.1 KFM07277.1 - 4.6e-05 23.7 0.8 0.0001 22.6 0.5 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Ly49 PF08391.5 KFM07277.1 - 0.049 13.7 0.0 0.093 12.8 0.0 1.4 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region C2-set PF05790.10 KFM07277.1 - 0.077 12.9 0.0 5.7 6.9 0.0 3.3 3 0 0 3 3 2 0 Immunoglobulin C2-set domain Shisa PF13908.1 KFM07277.1 - 0.11 12.6 0.0 0.11 12.6 0.0 3.3 3 0 0 3 3 2 0 Wnt and FGF inhibitory regulator TMEM154 PF15102.1 KFM07277.1 - 0.17 11.5 0.0 0.17 11.5 0.0 1.9 2 0 0 2 2 1 0 TMEM154 protein family P12 PF12669.2 KFM07277.1 - 0.45 10.7 0.8 0.94 9.7 0.6 1.5 1 0 0 1 1 1 0 Virus attachment protein p12 family DUF2659 PF10858.3 KFM07277.1 - 0.52 9.6 0.3 0.93 8.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2659) ADP_PFK_GK PF04587.10 KFM07278.1 - 1.2e-118 396.1 0.0 1.4e-118 395.9 0.0 1.0 1 0 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region TPR_11 PF13414.1 KFM07279.1 - 9.1e-50 166.1 15.2 1.5e-13 50.1 0.0 6.1 4 2 2 6 6 6 5 TPR repeat TPR_2 PF07719.12 KFM07279.1 - 7.9e-45 147.2 17.9 1.4e-05 24.6 0.0 10.7 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_1 PF00515.23 KFM07279.1 - 1e-41 138.8 19.6 1.3e-05 24.5 0.0 9.4 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_8 PF13181.1 KFM07279.1 - 4.4e-34 113.6 16.7 1.1e-05 24.8 0.0 9.3 7 1 2 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.1 KFM07279.1 - 8.5e-33 112.3 1.3 0.00012 22.6 0.0 6.8 4 2 3 7 7 7 7 Tetratricopeptide repeat TPR_19 PF14559.1 KFM07279.1 - 2.2e-28 98.4 8.3 9.8e-09 35.4 0.1 6.5 4 2 2 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.1 KFM07279.1 - 4.6e-27 93.7 24.6 3.2e-07 30.1 0.3 7.2 2 2 6 8 8 8 7 Tetratricopeptide repeat TPR_17 PF13431.1 KFM07279.1 - 1.7e-25 87.0 16.8 5.6e-07 29.2 0.0 9.2 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 KFM07279.1 - 7.1e-25 85.2 1.8 0.00013 22.2 0.0 8.7 3 2 7 10 10 9 5 Tetratricopeptide repeat TPR_9 PF13371.1 KFM07279.1 - 5.4e-20 71.0 0.0 2e-05 24.3 0.0 6.2 2 1 5 7 7 6 3 Tetratricopeptide repeat Apc3 PF12895.2 KFM07279.1 - 2.5e-19 69.2 23.6 5e-06 26.5 0.1 5.7 2 2 5 7 7 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KFM07279.1 - 4.9e-18 63.4 12.0 0.00043 19.8 0.0 8.6 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_6 PF13174.1 KFM07279.1 - 3.5e-13 49.0 14.2 0.24 11.9 0.0 10.1 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_15 PF13429.1 KFM07279.1 - 5.7e-09 35.4 8.7 0.0073 15.4 0.3 4.1 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_20 PF14561.1 KFM07279.1 - 7.3e-08 32.4 2.6 0.0057 16.7 0.0 4.7 3 2 0 4 4 4 1 Tetratricopeptide repeat NARP1 PF12569.3 KFM07279.1 - 1.2e-07 30.8 11.1 0.0047 15.7 0.2 4.2 3 2 1 4 4 4 3 NMDA receptor-regulated protein 1 TPR_10 PF13374.1 KFM07279.1 - 5.2e-06 26.1 17.2 0.17 11.8 0.1 7.9 9 0 0 9 9 8 1 Tetratricopeptide repeat Coatomer_E PF04733.9 KFM07279.1 - 0.00016 20.9 4.9 0.46 9.6 0.4 3.5 2 1 0 3 3 3 1 Coatomer epsilon subunit ChAPs PF09295.5 KFM07279.1 - 0.00019 20.3 0.8 0.017 13.9 0.1 2.7 2 1 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) BTAD PF03704.12 KFM07279.1 - 0.0076 16.5 3.2 3.7 7.8 0.0 4.3 3 2 0 4 4 4 1 Bacterial transcriptional activator domain MIT PF04212.13 KFM07279.1 - 0.019 14.8 7.9 3.2 7.6 0.0 5.3 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.1 KFM07279.1 - 0.028 14.3 7.8 7.1 6.6 0.0 4.9 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat Rapsyn_N PF10579.4 KFM07279.1 - 0.034 13.9 0.9 0.43 10.4 0.0 3.1 4 0 0 4 4 3 0 Rapsyn N-terminal myristoylation and linker region MAS20 PF02064.10 KFM07279.1 - 0.07 13.0 0.3 2.9 7.8 0.0 3.0 2 1 1 3 3 3 0 MAS20 protein import receptor IBR PF01485.16 KFM07280.1 - 6.8e-21 73.9 48.9 2.2e-14 53.0 6.9 4.8 3 1 1 4 4 4 2 IBR domain zf-C3HC4_2 PF13923.1 KFM07280.1 - 1.6e-06 28.0 6.4 1.6e-06 28.0 4.5 5.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM07280.1 - 1.3e-05 24.9 4.2 1.3e-05 24.9 2.9 4.3 2 1 2 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.20 KFM07280.1 - 0.00032 20.2 3.8 0.00032 20.2 2.6 5.3 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM07280.1 - 0.00072 19.2 5.9 0.00072 19.2 4.1 4.2 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFM07280.1 - 0.0025 17.6 5.2 0.0025 17.6 3.6 5.0 4 1 0 4 4 4 2 zinc finger of C3HC4-type, RING POTRA_2 PF08479.6 KFM07280.1 - 0.14 11.8 0.2 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 POTRA domain, ShlB-type DUF3287 PF11690.3 KFM07280.1 - 0.24 11.4 6.6 0.57 10.2 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) Glyco_hydro_20 PF00728.17 KFM07281.1 - 1.3e-84 284.4 0.0 1.5e-84 284.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 KFM07281.1 - 4.5e-11 43.5 0.0 8.4e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 KFM07281.1 - 0.0002 21.9 0.0 0.00034 21.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 RRM_1 PF00076.17 KFM07282.1 - 7.2e-16 57.5 0.0 1.3e-15 56.7 0.0 1.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM07282.1 - 3.5e-08 33.3 0.0 5.1e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM07282.1 - 0.00012 21.8 0.0 0.00016 21.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFM07283.1 - 5.7e-37 125.1 0.0 6.8e-18 64.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM07283.1 - 1.7e-26 91.9 0.0 2.2e-12 46.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM07283.1 - 3.2e-21 74.9 0.1 3.7e-10 39.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 KFM07283.1 - 0.0098 15.8 0.0 0.75 9.8 0.0 2.5 2 0 0 2 2 2 1 RNA binding domain RRM_3 PF08777.6 KFM07283.1 - 0.058 13.2 0.0 14 5.5 0.0 2.4 2 0 0 2 2 2 0 RNA binding motif PARP PF00644.15 KFM07284.1 - 5.1e-13 48.9 0.2 9.8e-13 47.9 0.1 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PK PF00224.16 KFM07285.1 - 1.8e-167 556.2 2.9 2.2e-167 556.0 2.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 KFM07285.1 - 6.1e-30 103.1 0.0 1.8e-29 101.6 0.0 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 KFM07285.1 - 0.00024 20.0 0.3 0.00055 18.8 0.2 1.6 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family GRAM PF02893.15 KFM07286.1 - 3.4e-16 58.5 0.1 8.5e-16 57.2 0.0 1.7 1 0 0 1 1 1 1 GRAM domain Peptidase_C48 PF02902.14 KFM07287.1 - 4e-12 46.2 2.4 6.7e-11 42.2 1.7 2.5 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Myosin_head PF00063.16 KFM07288.1 - 6.1e-208 692.2 4.0 3.2e-179 597.2 1.0 2.3 2 0 0 2 2 2 2 Myosin head (motor domain) RhoGAP PF00620.22 KFM07288.1 - 3e-48 163.2 0.3 3.9e-47 159.6 0.0 2.9 3 0 0 3 3 3 1 RhoGAP domain RA PF00788.18 KFM07288.1 - 1.4e-21 76.7 0.1 7.7e-21 74.3 0.0 2.5 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain IQ PF00612.22 KFM07288.1 - 5.1e-17 59.8 47.7 0.00015 21.0 0.1 7.3 6 1 1 7 7 7 5 IQ calmodulin-binding motif C1_1 PF00130.17 KFM07288.1 - 1.9e-05 24.2 12.3 3.6e-05 23.4 8.6 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) AAA_22 PF13401.1 KFM07288.1 - 0.0057 16.7 0.0 0.099 12.7 0.0 3.1 2 0 0 2 2 2 1 AAA domain HemX PF04375.9 KFM07288.1 - 2.4 6.6 17.0 0.61 8.6 6.6 2.2 2 0 0 2 2 2 0 HemX zf-C4 PF00105.13 KFM07289.1 - 3.6e-28 97.6 14.1 4e-28 97.4 8.6 1.9 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 KFM07289.1 - 5.9e-27 94.1 0.2 2.3e-26 92.2 0.1 1.8 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Ion_trans PF00520.26 KFM07291.1 - 5.3e-33 113.9 8.6 5.3e-33 113.9 5.9 1.4 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 KFM07291.1 - 5e-11 42.1 2.8 5e-11 42.1 2.0 2.7 3 0 0 3 3 3 1 Ion channel PKD_channel PF08016.7 KFM07291.1 - 0.98 7.7 9.3 0.35 9.2 2.3 2.1 1 1 1 2 2 2 0 Polycystin cation channel EF-hand_6 PF13405.1 KFM07292.1 - 9e-09 34.4 1.9 0.00097 18.8 0.1 3.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 KFM07292.1 - 1.2e-07 31.7 2.6 1.4e-06 28.3 0.3 3.4 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 KFM07292.1 - 1.2e-06 27.4 3.2 0.00043 19.3 0.1 3.9 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.1 KFM07292.1 - 0.00012 21.2 0.2 0.00091 18.4 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KFM07292.1 - 0.0066 16.0 1.4 0.063 12.9 0.2 2.1 1 1 1 2 2 2 2 EF-hand domain pair RIC3 PF15361.1 KFM07293.1 - 2.5e-15 57.0 0.2 2.9e-15 56.8 0.1 1.1 1 0 0 1 1 1 1 Resistance to inhibitors of cholinesterase homologue 3 DUF4366 PF14283.1 KFM07293.1 - 0.026 13.9 0.1 0.03 13.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) CAP PF00188.21 KFM07294.1 - 2.4e-13 50.6 6.5 4.2e-13 49.8 4.5 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.21 KFM07295.1 - 7.8e-20 71.6 1.8 9.7e-20 71.3 1.3 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.21 KFM07296.1 - 3.3e-20 72.8 3.8 4.4e-20 72.4 2.6 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family KH_1 PF00013.24 KFM07297.1 - 0.00024 20.6 0.0 0.00051 19.6 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 KFM07297.1 - 0.00032 20.2 0.0 0.0007 19.1 0.0 1.6 1 0 0 1 1 1 1 KH domain KH_4 PF13083.1 KFM07297.1 - 0.0086 15.6 0.1 0.024 14.2 0.0 1.7 2 0 0 2 2 2 1 KH domain Transferase PF02458.10 KFM07297.1 - 0.11 10.9 4.4 0.16 10.4 3.0 1.3 1 0 0 1 1 1 0 Transferase family NAP PF00956.13 KFM07298.1 - 6e-95 317.0 7.5 6e-95 317.0 5.2 1.9 3 0 0 3 3 3 1 Nucleosome assembly protein (NAP) DUF2229 PF09989.4 KFM07298.1 - 0.03 13.8 1.2 0.049 13.0 0.8 1.3 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF3486 PF11985.3 KFM07298.1 - 4.1 7.4 10.1 0.076 13.0 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3486) Cpn60_TCP1 PF00118.19 KFM07299.1 - 2.1e-07 29.9 0.0 0.00038 19.2 0.0 2.2 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family Kin17_mid PF10357.4 KFM07299.1 - 0.054 13.1 0.4 0.054 13.1 0.3 1.7 2 0 0 2 2 2 0 Domain of Kin17 curved DNA-binding protein Oxysterol_BP PF01237.13 KFM07300.1 - 4.8e-92 308.1 0.3 7.2e-92 307.5 0.2 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein PH PF00169.24 KFM07300.1 - 7.4e-10 38.9 0.3 2.4e-09 37.3 0.0 2.1 2 0 0 2 2 2 1 PH domain Ank_2 PF12796.2 KFM07301.1 - 2.2e-41 140.0 0.6 8.1e-16 58.1 0.0 4.2 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFM07301.1 - 7.7e-39 129.6 2.5 6.8e-10 38.2 0.3 6.5 7 0 0 7 7 7 5 Ankyrin repeat zf-DHHC PF01529.15 KFM07301.1 - 5.9e-38 129.9 15.1 5.9e-38 129.9 10.5 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_4 PF13637.1 KFM07301.1 - 1.4e-32 111.4 0.5 3.9e-10 39.9 0.0 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM07301.1 - 3.3e-32 107.3 1.3 1.1e-05 25.1 0.1 7.4 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 KFM07301.1 - 9.4e-30 101.9 3.9 7.6e-08 32.3 0.2 5.4 1 1 4 5 5 5 5 Ankyrin repeats (many copies) LIM PF00412.17 KFM07302.1 - 3.2e-30 103.9 28.1 2.9e-17 62.4 4.0 2.1 2 0 0 2 2 2 2 LIM domain DUF4428 PF14471.1 KFM07302.1 - 0.024 14.3 9.5 0.055 13.2 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) zf-C3HC4_2 PF13923.1 KFM07302.1 - 0.095 12.7 0.7 0.095 12.7 0.5 4.0 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.20 KFM07303.1 - 1.2e-55 188.4 0.0 1.9e-55 187.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM07303.1 - 5.2e-42 143.7 0.0 7.8e-42 143.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.3 KFM07303.1 - 3.8e-21 74.4 5.6 8e-20 70.1 1.0 2.5 2 0 0 2 2 2 2 Oxidative-stress-responsive kinase 1 C terminal Rad52_Rad22 PF04098.10 KFM07304.1 - 1.3e-53 180.9 0.6 1.7e-53 180.4 0.0 1.5 2 0 0 2 2 2 1 Rad52/22 family double-strand break repair protein Cast PF10174.4 KFM07305.1 - 4.3e-267 888.1 160.1 4.9e-267 888.0 111.0 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone ATG16 PF08614.6 KFM07305.1 - 0.0008 19.2 29.4 0.0021 17.8 8.3 9.5 1 1 7 8 8 8 4 Autophagy protein 16 (ATG16) DUF869 PF05911.6 KFM07305.1 - 0.0017 16.7 17.2 0.0017 16.7 11.9 5.8 1 1 3 6 6 6 2 Plant protein of unknown function (DUF869) IncA PF04156.9 KFM07305.1 - 1.4 8.4 157.9 0.047 13.2 15.7 8.3 1 1 5 6 6 6 0 IncA protein Reo_sigmaC PF04582.7 KFM07305.1 - 9.4 5.3 46.6 0.15 11.2 1.8 5.7 2 1 3 6 6 6 0 Reovirus sigma C capsid protein LRR_6 PF13516.1 KFM07306.1 - 4.3e-21 72.5 42.2 0.038 14.0 0.1 11.9 12 0 0 12 12 12 9 Leucine Rich repeat LRR_4 PF12799.2 KFM07306.1 - 6.8e-16 57.4 20.0 0.0065 16.0 0.8 7.3 2 2 5 8 8 8 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM07306.1 - 1.7e-13 48.5 26.8 1.2 9.4 0.0 10.9 9 2 0 9 9 9 4 Leucine Rich Repeat LRR_8 PF13855.1 KFM07306.1 - 1.6e-09 37.3 29.4 0.024 14.3 3.3 6.2 2 2 3 6 6 6 6 Leucine rich repeat LRR_7 PF13504.1 KFM07306.1 - 0.00088 19.0 37.5 16 6.2 0.1 11.3 11 1 1 12 12 12 1 Leucine rich repeat Ste50p-SAM PF09235.5 KFM07306.1 - 0.0023 17.9 4.5 0.21 11.6 0.2 4.4 4 1 1 5 5 5 1 Ste50p, sterile alpha motif LRR_2 PF07723.8 KFM07306.1 - 0.0043 17.4 12.6 2.6 8.6 0.0 6.7 6 0 0 6 6 6 1 Leucine Rich Repeat Bac_DnaA_C PF08299.6 KFM07306.1 - 0.057 13.2 0.0 0.2 11.5 0.0 2.0 1 0 0 1 1 1 0 Bacterial dnaA protein helix-turn-helix Antiterm PF03589.8 KFM07306.1 - 0.15 12.1 0.0 0.47 10.5 0.0 1.8 1 0 0 1 1 1 0 Antitermination protein wnt PF00110.14 KFM07307.1 - 2.8e-121 404.4 22.9 3.2e-121 404.2 15.9 1.0 1 0 0 1 1 1 1 wnt family HlyIII PF03006.15 KFM07308.1 - 7.1e-71 238.1 23.3 1e-70 237.6 16.1 1.2 1 0 0 1 1 1 1 Haemolysin-III related FeoB_C PF07664.7 KFM07308.1 - 2.7 7.4 7.0 5.8 6.4 0.4 3.3 3 0 0 3 3 3 0 Ferrous iron transport protein B C terminus VWA_N PF08399.6 KFM07309.1 - 6.6e-42 143.0 0.5 1.3e-41 142.0 0.4 1.5 1 0 0 1 1 1 1 VWA N-terminal Cache_1 PF02743.13 KFM07309.1 - 1.2e-25 88.8 0.0 2.8e-24 84.4 0.0 2.5 2 0 0 2 2 2 1 Cache domain VWA_3 PF13768.1 KFM07309.1 - 5.6e-15 55.3 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 KFM07309.1 - 8.7e-14 51.9 0.0 1.4e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KFM07309.1 - 6e-12 45.6 0.0 1.1e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 KFM07309.1 - 0.051 12.7 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein CobT_C PF11775.3 KFM07309.1 - 0.15 11.4 0.0 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain LRR_8 PF13855.1 KFM07310.1 - 6.1e-30 102.7 29.8 8.2e-12 44.7 0.4 3.3 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 KFM07310.1 - 3.9e-13 48.6 16.3 0.00021 20.8 0.1 3.5 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRRNT PF01462.13 KFM07310.1 - 1.3e-09 37.2 2.7 6e-09 35.1 2.0 2.2 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_5 PF13306.1 KFM07310.1 - 5.4e-08 32.6 0.0 1e-06 28.5 0.0 2.3 2 1 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_7 PF13504.1 KFM07310.1 - 1.3e-07 30.6 16.7 0.13 12.5 0.1 6.2 6 0 0 6 6 6 4 Leucine rich repeat LRR_1 PF00560.28 KFM07310.1 - 1.6e-07 30.3 25.5 0.0083 16.0 0.5 6.7 6 1 0 6 6 6 4 Leucine Rich Repeat LRR_9 PF14580.1 KFM07310.1 - 0.0062 16.1 2.1 0.081 12.4 0.4 2.0 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.1 KFM07310.1 - 0.56 10.4 17.1 7.3 7.0 0.3 5.4 5 0 0 5 5 5 0 Leucine Rich repeat DCP1 PF06058.8 KFM07311.1 - 2.1e-34 118.2 0.0 4.7e-34 117.0 0.0 1.6 1 0 0 1 1 1 1 Dcp1-like decapping family SEFIR PF08357.6 KFM07312.1 - 1.1e-43 148.8 0.0 2e-43 148.0 0.0 1.4 1 0 0 1 1 1 1 SEFIR domain Hydrolase_6 PF13344.1 KFM07313.1 - 2.4e-12 46.6 0.0 4.6e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFM07313.1 - 2.8e-07 30.1 0.0 7.8e-07 28.7 0.0 1.9 1 1 0 1 1 1 1 HAD-hyrolase-like A_deaminase PF00962.17 KFM07314.1 - 8e-60 202.4 0.0 1.3e-59 201.8 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.6 KFM07314.1 - 1.2e-21 76.5 0.0 2.5e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal vATP-synt_E PF01991.13 KFM07315.1 - 2.1e-71 239.3 11.6 2.5e-71 239.0 8.1 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit ATP-synt_B PF00430.13 KFM07315.1 - 0.015 15.0 0.6 0.015 15.0 0.4 3.0 2 1 0 3 3 3 0 ATP synthase B/B' CF(0) NifW PF03206.9 KFM07315.1 - 0.031 14.3 3.4 0.048 13.7 2.0 1.6 1 1 0 1 1 1 0 Nitrogen fixation protein NifW DUF4288 PF14119.1 KFM07315.1 - 0.068 13.3 2.9 0.96 9.6 1.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4288) DUF4026 PF13218.1 KFM07315.1 - 0.088 11.6 3.8 0.11 11.2 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4026) Gluconate_2-dh3 PF13618.1 KFM07315.1 - 6 7.0 5.9 45 4.1 4.1 2.0 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 Bcl-2 PF00452.14 KFM07316.1 - 1e-11 44.8 0.0 1.6e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family DUF842 PF05811.8 KFM07316.1 - 0.075 12.5 0.1 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) DUF3770 PF12603.3 KFM07316.1 - 0.078 12.0 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3770) DUF1722 PF08349.6 KFM07316.1 - 0.089 12.6 0.6 0.51 10.2 0.4 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1722) DUF4549 PF15082.1 KFM07316.1 - 0.11 12.0 2.1 0.25 10.9 1.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4549) BID PF06393.6 KFM07317.1 - 1.8e-66 223.2 0.5 1.9e-66 223.1 0.4 1.0 1 0 0 1 1 1 1 BH3 interacting domain (BID) CRM1_C PF08767.6 KFM07317.1 - 0.046 12.6 0.4 0.069 12.0 0.3 1.4 1 1 0 1 1 1 0 CRM1 C terminal TAFH PF07531.9 KFM07317.1 - 0.075 12.6 0.3 0.88 9.2 0.0 2.4 3 0 0 3 3 3 0 NHR1 homology to TAF Phage_int_SAM_2 PF12834.2 KFM07317.1 - 0.09 13.1 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Phage integrase, N-terminal CH PF00307.26 KFM07318.1 - 2e-17 63.1 0.0 6.6e-17 61.5 0.0 2.0 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFM07318.1 - 3.6e-12 45.7 0.0 1.1e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 CAMSAP CH domain LIM PF00412.17 KFM07318.1 - 2.7e-09 36.9 10.7 5.2e-09 36.0 7.4 1.5 1 0 0 1 1 1 1 LIM domain FAD_binding_3 PF01494.14 KFM07318.1 - 1.4e-05 24.2 0.0 2.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFM07318.1 - 0.00055 18.9 0.1 0.0014 17.5 0.1 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KFM07318.1 - 0.0006 18.3 0.0 0.0011 17.5 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 KFM07318.1 - 0.00062 19.6 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFM07318.1 - 0.00063 18.7 0.0 0.0012 17.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KFM07318.1 - 0.0019 18.5 0.1 0.0072 16.7 0.0 2.1 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFM07318.1 - 0.0028 17.7 0.0 0.0054 16.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KFM07318.1 - 0.0031 17.7 0.0 0.0094 16.1 0.0 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding Thi4 PF01946.12 KFM07318.1 - 0.0034 16.4 0.0 0.0066 15.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 KFM07318.1 - 0.0066 16.4 0.0 0.021 14.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KFM07318.1 - 0.025 13.4 0.0 0.042 12.7 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 KFM07318.1 - 0.04 13.4 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pex26 PF07163.7 KFM07319.1 - 1.5e-84 283.5 2.3 1.8e-84 283.3 1.6 1.0 1 0 0 1 1 1 1 Pex26 protein Tubulin PF00091.20 KFM07320.1 - 1.6e-68 230.7 0.0 2.2e-68 230.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFM07320.1 - 3.3e-49 166.1 0.0 5.1e-49 165.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KFM07320.1 - 0.0039 16.6 0.0 0.0067 15.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain UCH PF00443.24 KFM07321.1 - 4.5e-39 134.1 4.4 5.3e-39 133.9 3.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFM07321.1 - 1.2e-25 90.6 6.4 3.6e-25 89.0 4.4 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Viral_protease PF08715.5 KFM07321.1 - 0.011 14.8 0.3 0.021 13.9 0.2 1.4 1 0 0 1 1 1 0 Papain like viral protease PAN_3 PF08277.7 KFM07321.1 - 0.62 9.7 9.5 52 3.5 6.6 2.8 2 1 0 2 2 2 0 PAN-like domain Aldo_ket_red PF00248.16 KFM07323.1 - 4.9e-58 196.1 0.0 5.9e-58 195.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family B5 PF03484.10 KFM07323.1 - 0.14 11.9 0.0 1.6 8.5 0.0 2.5 2 1 1 3 3 3 0 tRNA synthetase B5 domain Aldo_ket_red PF00248.16 KFM07324.1 - 1.2e-56 191.5 0.0 1.4e-56 191.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1187 PF06688.6 KFM07324.1 - 0.69 10.0 4.0 80 3.4 0.0 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF1187) His_Phos_1 PF00300.17 KFM07325.1 - 6.1e-43 146.6 0.0 8.2e-43 146.2 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Caldesmon PF02029.10 KFM07326.1 - 1.5e-212 706.4 215.4 1.6e-160 534.8 65.2 2.6 1 1 1 2 2 2 2 Caldesmon Aldo_ket_red PF00248.16 KFM07327.1 - 7.4e-56 189.0 0.0 8.7e-56 188.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ras PF00071.17 KFM07328.1 - 6.9e-26 90.5 0.0 7.5e-26 90.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM07328.1 - 2.8e-10 40.7 0.0 3.4e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM07328.1 - 0.0021 17.3 0.0 0.0025 17.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Y_phosphatase PF00102.22 KFM07329.1 - 9.7e-85 283.6 1.8 2.5e-84 282.2 1.3 1.8 1 0 0 1 1 1 1 Protein-tyrosine phosphatase fn3 PF00041.16 KFM07329.1 - 6.2e-29 99.9 17.2 5.8e-09 35.9 0.8 6.1 5 0 0 5 5 5 5 Fibronectin type III domain DSPc PF00782.15 KFM07329.1 - 0.00016 21.2 0.0 0.00039 19.9 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 KFM07329.1 - 0.00018 21.5 0.2 0.00049 20.1 0.0 1.9 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 KFM07329.1 - 0.00041 20.6 0.0 0.00087 19.5 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTB PF08416.8 KFM07330.1 - 1.3e-52 177.0 1.6 2.7e-52 176.0 1.1 1.5 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SH3_1 PF00018.23 KFM07330.1 - 4.3e-10 38.8 0.1 1.1e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFM07330.1 - 1e-06 28.1 0.0 2.3e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFM07330.1 - 1.6e-05 24.3 0.0 3.1e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PID PF00640.18 KFM07330.1 - 3.5e-05 23.7 1.3 7.1e-05 22.8 0.2 2.1 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) SH3_3 PF08239.6 KFM07330.1 - 0.00044 20.3 0.1 0.0014 18.7 0.0 1.9 2 0 0 2 2 2 1 Bacterial SH3 domain SAM_PNT PF02198.11 KFM07330.1 - 0.083 12.6 0.0 0.26 11.0 0.0 1.8 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain WD40 PF00400.27 KFM07331.1 - 1.2e-38 129.5 0.2 3.4e-11 42.5 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat PQQ_2 PF13360.1 KFM07331.1 - 0.00066 19.2 0.0 0.0037 16.7 0.0 2.1 1 1 0 1 1 1 1 PQQ-like domain Me-amine-dh_H PF06433.6 KFM07331.1 - 0.037 12.6 0.1 1.5 7.3 0.0 2.6 3 1 0 3 3 3 0 Methylamine dehydrogenase heavy chain (MADH) DUF3312 PF11768.3 KFM07331.1 - 0.067 11.3 0.0 8.6 4.4 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3312) DeoC PF01791.4 KFM07332.1 - 3.7e-39 134.4 0.1 4.2e-39 134.2 0.1 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase PTR2 PF00854.16 KFM07333.1 - 6.6e-26 90.9 13.5 1.7e-17 63.2 2.4 2.2 1 1 1 2 2 2 2 POT family MAPEG PF01124.13 KFM07334.1 - 1.7e-22 79.4 0.3 2e-22 79.1 0.2 1.1 1 0 0 1 1 1 1 MAPEG family LIM PF00412.17 KFM07335.1 - 1.1e-30 105.4 22.3 2.4e-15 56.3 5.8 2.0 2 0 0 2 2 2 2 LIM domain C1_4 PF07975.7 KFM07335.1 - 3.9 7.5 22.7 0.35 10.8 4.9 2.5 2 0 0 2 2 2 0 TFIIH C1-like domain Ras PF00071.17 KFM07336.1 - 3.9e-19 68.6 0.0 5.1e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM07336.1 - 3.1e-07 30.8 0.0 7e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein PI3_PI4_kinase PF00454.22 KFM07337.1 - 3.4e-46 157.6 1.3 9.8e-46 156.1 0.4 2.2 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 KFM07337.1 - 6.6e-31 106.9 3.2 6.6e-31 106.9 2.2 2.6 4 0 0 4 4 4 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PX PF00787.19 KFM07337.1 - 3.6e-12 46.0 4.1 3.8e-12 46.0 0.8 2.6 3 0 0 3 3 3 1 PX domain PI3K_C2 PF00792.19 KFM07337.1 - 7.6e-12 45.2 0.1 2.6e-11 43.4 0.1 1.9 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.13 KFM07337.1 - 8.2e-06 25.7 0.2 8.6e-05 22.4 0.0 2.7 3 0 0 3 3 3 1 PI3-kinase family, ras-binding domain C2 PF00168.25 KFM07337.1 - 3.3e-05 23.6 0.0 0.00053 19.7 0.0 2.5 2 0 0 2 2 2 1 C2 domain PI-PLC-X PF00388.14 KFM07339.1 - 1.9e-61 205.7 0.0 3.2e-61 205.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KFM07339.1 - 7.4e-44 148.5 0.1 1.4e-43 147.5 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 KFM07339.1 - 4.3e-22 77.9 0.3 1.1e-21 76.6 0.2 1.7 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 KFM07339.1 - 4.8e-16 58.3 0.2 1.4e-15 56.9 0.0 2.0 2 0 0 2 2 2 1 C2 domain zf-C2H2 PF00096.21 KFM07341.1 - 4.9e-06 26.5 14.3 0.45 10.9 3.4 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM07341.1 - 2.1e-05 24.5 0.0 2.1e-05 24.5 0.0 3.1 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM07341.1 - 7.5e-05 22.7 13.4 1.2 9.6 0.0 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger RVT_1 PF00078.22 KFM07342.1 - 0.014 14.7 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) PDEase_I PF00233.14 KFM07343.1 - 2e-45 155.3 0.1 3.8e-41 141.3 0.0 2.3 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase OATP PF03137.15 KFM07344.1 - 2.9e-176 586.7 10.8 3.4e-176 586.4 7.5 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 KFM07344.1 - 3.6e-25 88.4 15.6 2.4e-20 72.5 1.0 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily Kazal_2 PF07648.10 KFM07344.1 - 5.4e-11 42.2 5.6 1.3e-10 41.0 3.9 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Sugar_tr PF00083.19 KFM07344.1 - 1.1e-07 30.8 1.0 1.1e-07 30.8 0.7 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter Kazal_1 PF00050.16 KFM07344.1 - 0.00014 21.8 3.5 0.00036 20.4 2.4 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain OATP PF03137.15 KFM07345.1 - 7.2e-177 588.7 19.6 8.3e-177 588.4 13.6 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 KFM07345.1 - 1.3e-21 76.7 26.4 1.9e-17 63.0 5.4 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily Kazal_2 PF07648.10 KFM07345.1 - 4.6e-10 39.2 5.7 1.3e-09 37.7 4.0 1.9 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 KFM07345.1 - 0.0054 16.7 6.2 0.017 15.1 4.3 1.8 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Calc_CGRP_IAPP PF00214.14 KFM07346.1 - 6.5e-23 81.1 0.1 7.5e-23 81.0 0.1 1.0 1 0 0 1 1 1 1 Calcitonin / CGRP / IAPP family DUF2706 PF10913.3 KFM07346.1 - 0.03 13.9 0.1 0.049 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2706) Pyr_redox_2 PF07992.9 KFM07347.1 - 7.4e-16 58.6 0.0 1.5e-15 57.6 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFM07347.1 - 0.01 15.9 0.0 0.25 11.3 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Helicase_C PF00271.26 KFM07348.1 - 3.7e-18 65.1 0.0 1.7e-17 63.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFM07348.1 - 8.4e-17 61.1 0.0 3e-16 59.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase RQC PF09382.5 KFM07348.1 - 5.6e-05 22.8 0.1 0.00037 20.1 0.0 2.5 2 1 0 2 2 2 1 RQC domain ResIII PF04851.10 KFM07348.1 - 0.00082 19.2 0.0 0.011 15.5 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit KOW PF00467.24 KFM07348.1 - 0.078 12.7 0.2 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 KOW motif Osmo_CC PF08946.5 KFM07348.1 - 0.69 9.9 4.2 2.1 8.4 2.9 1.9 1 0 0 1 1 1 0 Osmosensory transporter coiled coil Got1 PF04178.7 KFM07349.1 - 1.6e-21 76.5 15.4 1.8e-21 76.4 10.7 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF308 PF03729.8 KFM07349.1 - 0.011 15.6 11.3 0.011 15.6 7.8 2.4 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) Fzo_mitofusin PF04799.8 KFM07349.1 - 0.039 13.3 0.4 0.054 12.8 0.3 1.2 1 0 0 1 1 1 0 fzo-like conserved region Aminotran_4 PF01063.14 KFM07350.1 - 3.2e-24 85.6 0.0 4.2e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV HMG_box PF00505.14 KFM07352.1 - 4.2e-22 78.1 3.6 4.2e-22 78.1 2.5 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFM07352.1 - 1.2e-08 35.1 1.0 1.2e-08 35.1 0.7 3.3 4 0 0 4 4 4 1 HMG-box domain Exonuc_VII_L PF02601.10 KFM07352.1 - 0.013 14.7 0.9 0.013 14.7 0.6 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit HemX PF04375.9 KFM07352.1 - 0.052 12.1 19.6 0.023 13.2 8.7 2.3 2 0 0 2 2 2 0 HemX Atg14 PF10186.4 KFM07352.1 - 4.3 6.1 15.0 0.58 9.0 6.6 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Choline_kinase PF01633.15 KFM07353.1 - 2.9e-60 203.4 0.1 3.8e-60 203.0 0.1 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 KFM07353.1 - 5.6e-14 52.4 0.0 8.3e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KFM07353.1 - 2.9e-05 23.3 0.4 5.8e-05 22.3 0.3 1.6 1 1 0 1 1 1 1 Ecdysteroid kinase Caps_assemb_Wzi PF14052.1 KFM07353.1 - 0.021 13.7 1.6 0.028 13.3 1.1 1.1 1 0 0 1 1 1 0 Capsule assembly protein Wzi C2 PF00168.25 KFM07354.1 - 1.5e-11 43.9 0.3 2.9e-11 43.0 0.2 1.5 1 0 0 1 1 1 1 C2 domain YbjQ_1 PF01906.12 KFM07354.1 - 2.4e-07 31.1 3.2 0.011 16.1 0.0 4.6 4 1 0 4 4 4 2 Putative heavy-metal-binding Glyco_transf_29 PF00777.13 KFM07355.1 - 4.4e-75 252.2 0.0 4.9e-75 252.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Sulfotransfer_1 PF00685.22 KFM07356.1 - 1.1e-64 218.3 4.3 3.6e-62 210.0 3.0 2.1 1 1 0 1 1 1 1 Sulfotransferase domain CTP_transf_3 PF02348.14 KFM07357.1 - 1.4e-30 106.5 0.0 2.1e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase Hydrolase_3 PF08282.7 KFM07357.1 - 7.5e-06 25.6 0.4 0.00026 20.6 0.0 2.9 2 2 2 4 4 4 1 haloacid dehalogenase-like hydrolase ABC_membrane PF00664.18 KFM07358.1 - 6.4e-65 219.2 26.6 1.1e-33 116.8 3.5 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFM07358.1 - 3.3e-52 176.4 0.2 1e-24 87.3 0.0 3.5 4 0 0 4 4 3 2 ABC transporter AAA_21 PF13304.1 KFM07358.1 - 1.1e-08 35.3 0.9 0.018 14.9 0.1 4.3 2 2 1 3 3 3 2 AAA domain SMC_N PF02463.14 KFM07358.1 - 4.9e-07 29.1 7.2 0.015 14.5 0.0 4.3 3 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KFM07358.1 - 1e-06 28.3 0.0 0.0051 16.2 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KFM07358.1 - 3e-05 23.4 0.7 0.046 13.2 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 KFM07358.1 - 8.3e-05 21.8 0.3 0.029 13.5 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 KFM07358.1 - 0.00018 21.9 0.0 0.7 10.4 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 KFM07358.1 - 0.0016 18.3 0.0 1.2 9.1 0.0 3.0 3 0 0 3 3 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 KFM07358.1 - 0.0037 16.3 0.1 0.33 10.0 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin ABC_ATPase PF09818.4 KFM07358.1 - 0.004 15.7 0.7 1 7.8 0.0 3.2 3 1 0 3 3 3 1 Predicted ATPase of the ABC class AAA_10 PF12846.2 KFM07358.1 - 0.0048 16.3 0.5 1.2 8.5 0.0 2.5 2 1 0 2 2 2 1 AAA-like domain AAA_22 PF13401.1 KFM07358.1 - 0.0073 16.4 0.1 5.5 7.1 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFM07358.1 - 0.0091 15.9 0.3 0.23 11.4 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain T2SE PF00437.15 KFM07358.1 - 0.015 14.2 0.0 3.7 6.3 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Arch_ATPase PF01637.13 KFM07358.1 - 0.025 14.3 0.1 0.3 10.7 0.0 2.7 3 0 0 3 3 3 0 Archaeal ATPase DUF815 PF05673.8 KFM07358.1 - 0.029 13.3 0.0 3.3 6.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATP-synt_ab PF00006.20 KFM07358.1 - 0.031 13.7 0.5 1.9 7.9 0.1 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activat PF00158.21 KFM07358.1 - 0.079 12.4 0.1 2.3 7.6 0.0 2.5 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_17 PF13207.1 KFM07358.1 - 0.24 12.2 1.1 7.7 7.3 0.0 3.4 3 0 0 3 3 3 0 AAA domain FAM177 PF14774.1 KFM07358.1 - 0.38 10.6 5.1 1.6 8.6 3.5 2.1 1 0 0 1 1 1 0 FAM177 family Dynamin_N PF00350.18 KFM07358.1 - 0.38 10.5 2.2 1.1 9.0 0.0 2.7 2 0 0 2 2 2 0 Dynamin family AAA_23 PF13476.1 KFM07358.1 - 1.7 8.9 13.3 26 5.0 0.0 3.4 2 1 0 2 2 2 0 AAA domain IRK PF01007.15 KFM07359.1 - 7.8e-161 534.4 2.7 9.6e-161 534.1 1.9 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ldh_1_N PF00056.18 KFM07360.1 - 2.6e-41 140.7 0.1 4e-41 140.1 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KFM07360.1 - 1.9e-29 102.5 0.0 2.7e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.11 KFM07360.1 - 0.00026 20.3 0.0 0.00046 19.5 0.0 1.4 1 0 0 1 1 1 1 Family 4 glycosyl hydrolase Glycogen_syn PF05693.8 KFM07361.1 - 0 1172.8 0.0 0 1172.5 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 KFM07361.1 - 2.1e-07 30.5 0.0 3.4e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Spexin PF15171.1 KFM07362.1 - 2e-40 136.6 1.7 2e-40 136.6 1.2 1.5 2 0 0 2 2 2 1 Neuropeptide secretory protein family, NPQ, spexin MRVI1 PF05781.7 KFM07364.1 - 5.7e-143 477.1 10.5 6.3e-143 477.0 7.3 1.0 1 0 0 1 1 1 1 MRVI1 protein SSFA2_C PF14723.1 KFM07364.1 - 0.032 13.9 1.1 0.063 13.0 0.7 1.4 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus DUF919 PF06034.6 KFM07364.1 - 0.071 12.7 5.7 0.035 13.7 1.7 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) RasGAP_C PF03836.10 KFM07364.1 - 0.16 11.6 6.1 1 9.0 0.4 2.4 1 1 1 2 2 2 0 RasGAP C-terminus Casc1 PF12366.3 KFM07365.1 - 2.1e-06 27.4 10.6 0.028 13.9 0.0 4.6 4 0 0 4 4 4 3 Cancer susceptibility candidate 1 Complex1_LYR PF05347.10 KFM07366.1 - 2.7e-14 52.7 0.7 3e-14 52.5 0.0 1.4 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KFM07366.1 - 8e-13 48.3 0.2 1.2e-12 47.7 0.1 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 KFM07366.1 - 5.6e-08 33.2 0.8 6.1e-08 33.0 0.6 1.0 1 0 0 1 1 1 1 Complex1_LYR-like Nbl1_Borealin_N PF10444.4 KFM07366.1 - 0.023 14.0 0.1 0.035 13.4 0.1 1.3 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal Ras PF00071.17 KFM07367.1 - 2.5e-58 196.0 0.0 3e-58 195.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM07367.1 - 2.7e-20 73.0 0.0 4.6e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM07367.1 - 7.8e-10 38.2 0.0 9.8e-10 37.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFM07367.1 - 2e-08 33.8 0.2 1.5e-07 31.0 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFM07367.1 - 9e-06 25.6 0.0 1.2e-05 25.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase ArgK PF03308.11 KFM07367.1 - 0.00028 19.7 0.1 0.0053 15.5 0.0 2.1 2 0 0 2 2 2 1 ArgK protein Gtr1_RagA PF04670.7 KFM07367.1 - 0.0017 17.5 0.0 0.0021 17.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 KFM07367.1 - 0.002 17.4 0.0 0.017 14.4 0.0 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF2075 PF09848.4 KFM07367.1 - 0.011 14.7 0.1 1.4 7.7 0.0 2.0 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.13 KFM07367.1 - 0.013 14.9 0.0 4.6 6.6 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.12 KFM07367.1 - 0.016 14.7 0.4 0.46 9.9 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 KFM07367.1 - 0.026 14.6 0.1 0.73 9.9 0.0 2.6 1 1 1 2 2 2 0 AAA domain AAA_25 PF13481.1 KFM07367.1 - 0.026 13.9 0.0 0.075 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 KFM07367.1 - 0.035 13.1 0.4 0.073 12.0 0.0 1.9 2 1 0 2 2 2 0 Septin DUF258 PF03193.11 KFM07367.1 - 0.052 12.7 0.7 0.11 11.7 0.2 1.9 2 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 KFM07367.1 - 0.1 12.5 0.0 0.17 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KFM07367.1 - 0.1 12.5 0.0 1.6 8.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain ThiF PF00899.16 KFM07367.1 - 0.16 11.7 0.5 2.8 7.7 0.1 2.2 2 0 0 2 2 2 0 ThiF family Yae1_N PF09811.4 KFM07368.1 - 2.3e-10 39.8 29.0 0.00031 20.2 11.8 3.1 2 1 0 2 2 2 2 Essential protein Yae1, N terminal RA PF00788.18 KFM07369.1 - 1.1e-05 25.8 0.0 3.2e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain TBPIP PF07106.8 KFM07369.1 - 0.0088 15.6 15.9 0.0088 15.6 11.0 3.2 1 1 2 3 3 3 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Reo_sigmaC PF04582.7 KFM07369.1 - 0.024 13.8 4.6 0.89 8.6 1.3 3.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Herpes_IE68 PF02479.11 KFM07369.1 - 0.042 13.0 4.8 0.27 10.4 0.6 2.5 2 0 0 2 2 2 0 Herpesvirus immediate early protein Tropomyosin PF00261.15 KFM07369.1 - 0.19 10.7 42.7 0.15 11.0 18.8 2.3 1 1 1 2 2 2 0 Tropomyosin Tropomyosin_1 PF12718.2 KFM07369.1 - 0.24 11.2 45.6 6.3 6.6 18.8 2.8 2 1 1 3 3 3 0 Tropomyosin like DUF3584 PF12128.3 KFM07369.1 - 0.86 6.8 33.8 1.3 6.3 23.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4200 PF13863.1 KFM07369.1 - 3.1 7.7 46.4 1.3 8.9 4.3 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) Fib_alpha PF08702.5 KFM07369.1 - 5.2 7.1 28.6 1.6 8.8 3.2 3.4 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Sterile PF03015.14 KFM07369.1 - 8.6 6.6 8.4 0.69 10.2 1.1 2.4 2 1 1 3 3 3 0 Male sterility protein HLH PF00010.21 KFM07370.1 - 5.6e-12 45.1 0.8 1.1e-11 44.1 0.5 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.8 KFM07370.1 - 9.2e-12 44.5 0.2 2.6e-11 43.0 0.2 1.8 1 0 0 1 1 1 1 Hairy Orange NatB_MDM20 PF09797.4 KFM07370.1 - 0.023 13.4 0.1 0.031 12.9 0.1 1.1 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit DUF2779 PF11074.3 KFM07370.1 - 0.035 14.1 0.2 0.47 10.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function(DUF2779) HTH_Mga PF08280.6 KFM07370.1 - 0.15 11.8 1.0 5.1 6.9 0.0 2.5 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain CD20 PF04103.10 KFM07371.1 - 2.3e-17 63.3 13.7 3e-17 62.9 9.5 1.1 1 0 0 1 1 1 1 CD20-like family DUF4064 PF13273.1 KFM07371.1 - 0.0079 16.2 5.8 0.12 12.5 0.1 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF4064) ABC2_membrane_4 PF12730.2 KFM07371.1 - 0.037 13.1 8.3 0.39 9.8 1.7 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein Mito_morph_reg PF14972.1 KFM07371.1 - 0.13 11.6 2.8 0.11 11.9 0.7 1.7 2 0 0 2 2 2 0 Mitochondrial morphogenesis regulator UPF0093 PF03653.8 KFM07371.1 - 0.17 11.8 3.8 2.2 8.2 0.4 2.7 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0093) PgaD PF13994.1 KFM07371.1 - 1.7 8.1 5.1 1.7 8.1 0.2 2.2 2 0 0 2 2 2 0 PgaD-like protein TcpE PF12648.2 KFM07371.1 - 4.1 7.6 6.1 0.4 10.8 0.6 1.9 2 0 0 2 2 2 0 TcpE family Bax1-I PF01027.15 KFM07371.1 - 9.5 5.7 16.6 6.2 6.3 6.3 2.2 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 DUF2151 PF10221.4 KFM07374.1 - 0 1028.7 3.0 0 1028.5 2.1 1.0 1 0 0 1 1 1 1 Cell cycle and development regulator DUF837 PF05769.6 KFM07375.1 - 1e-75 253.2 26.2 1.2e-75 253.0 18.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF837) Tho2 PF11262.3 KFM07375.1 - 0.0025 16.9 4.9 0.0025 16.9 3.4 2.0 1 1 1 2 2 2 1 Transcription factor/nuclear export subunit protein 2 ZYG-11_interact PF05884.7 KFM07375.1 - 0.25 10.3 2.0 0.41 9.6 1.4 1.3 1 0 0 1 1 1 0 Interactor of ZYG-11 CotJB PF12652.2 KFM07375.1 - 0.27 11.3 2.1 0.83 9.7 0.1 2.3 2 0 0 2 2 2 0 CotJB protein FUSC PF04632.7 KFM07375.1 - 0.32 9.3 5.5 0.38 9.1 3.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3452 PF11934.3 KFM07375.1 - 1.6 8.0 4.5 4.4 6.6 3.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3452) bZIP_1 PF00170.16 KFM07375.1 - 3 7.8 21.6 2.1 8.3 0.4 4.5 3 2 1 4 4 4 0 bZIP transcription factor ArsA_ATPase PF02374.10 KFM07375.1 - 4.6 6.1 11.3 0.48 9.4 1.8 2.1 1 1 1 2 2 2 0 Anion-transporting ATPase Mto2_bdg PF12808.2 KFM07375.1 - 5 7.3 17.1 2.8 8.1 3.1 3.5 3 1 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Sec20 PF03908.8 KFM07375.1 - 5.1 6.8 13.8 7.1 6.4 0.2 3.4 1 1 3 4 4 4 0 Sec20 DOG1 PF14144.1 KFM07375.1 - 7.7 6.6 6.8 12 6.0 0.3 3.1 2 1 1 3 3 3 0 Seed dormancy control NYD-SP28_assoc PF14775.1 KFM07375.1 - 7.7 6.2 14.9 1.9 8.2 1.6 3.3 3 1 0 3 3 3 0 Sperm tail C-terminal domain DUF4203 PF13886.1 KFM07376.1 - 3.7e-54 183.3 31.8 4.7e-54 183.0 22.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Med21 PF11221.3 KFM07377.1 - 1.2e-25 90.1 0.3 1.4e-25 89.9 0.2 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex TelA PF05816.6 KFM07377.1 - 2.8e-06 26.2 0.0 3.1e-06 26.1 0.0 1.0 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) DUF3717 PF12512.3 KFM07377.1 - 0.027 14.0 0.2 0.06 12.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3717) Leu_zip PF15294.1 KFM07377.1 - 0.03 13.4 0.1 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Leucine zipper Utp21 PF04192.7 KFM07377.1 - 0.054 12.5 0.3 0.38 9.8 0.0 2.0 1 1 1 2 2 2 0 Utp21 specific WD40 associated putative domain DUF2730 PF10805.3 KFM07377.1 - 0.055 13.2 0.0 0.08 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Pkinase PF00069.20 KFM07378.1 - 3.6e-60 203.3 0.2 1.7e-59 201.0 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM07378.1 - 4.2e-27 94.8 2.6 5.4e-19 68.2 0.2 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 KFM07378.1 - 2.2e-05 24.8 0.9 4.4e-05 23.9 0.6 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KFM07378.1 - 0.0013 17.7 3.1 0.0026 16.7 0.0 2.5 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.9 KFM07378.1 - 0.0019 17.2 0.8 0.0031 16.6 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFM07378.1 - 0.0096 15.6 0.1 0.17 11.5 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family PAS_11 PF14598.1 KFM07379.1 - 9.1e-29 99.6 0.1 2.2e-24 85.5 0.1 2.4 2 0 0 2 2 2 2 PAS domain PAS PF00989.19 KFM07379.1 - 3.5e-23 81.5 0.0 7.3e-11 41.8 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.6 KFM07379.1 - 1.5e-22 79.4 0.0 3.3e-14 52.7 0.0 2.6 2 0 0 2 2 2 2 PAS fold HLH PF00010.21 KFM07379.1 - 1.5e-15 56.6 2.6 3.9e-15 55.2 1.5 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.1 KFM07379.1 - 1.2e-13 51.3 0.0 8.4e-07 29.3 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 KFM07379.1 - 3.4e-07 30.2 0.0 0.0026 17.7 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.1 KFM07379.1 - 0.00011 21.9 0.0 0.036 13.9 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_2 PF08446.6 KFM07379.1 - 0.017 15.5 0.0 0.051 14.0 0.0 1.7 2 0 0 2 2 2 0 PAS fold SAM_1 PF00536.25 KFM07380.1 - 3e-37 126.6 10.1 6.7e-16 58.2 0.3 4.0 4 0 0 4 4 4 3 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFM07380.1 - 3.2e-32 110.1 9.2 1.8e-14 53.3 0.0 4.0 4 0 0 4 4 4 3 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 KFM07380.1 - 0.00041 20.0 3.6 0.041 13.6 0.2 3.2 3 0 0 3 3 3 1 Sterile alpha motif (SAM)/Pointed domain Integrase_DNA PF02920.10 KFM07380.1 - 0.0016 17.8 3.9 0.0045 16.3 2.7 1.9 1 0 0 1 1 1 1 DNA binding domain of tn916 integrase DUF4407 PF14362.1 KFM07380.1 - 0.0075 15.2 10.7 0.12 11.2 2.4 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4407) Bacillus_HBL PF05791.6 KFM07380.1 - 0.49 9.7 10.7 0.38 10.0 4.6 2.3 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Reo_sigmaC PF04582.7 KFM07380.1 - 1.6 7.8 4.6 4.7 6.2 1.5 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF16 PF01519.11 KFM07380.1 - 2.3 8.4 17.4 0.053 13.7 1.9 3.4 3 0 0 3 3 3 0 Protein of unknown function DUF16 ADIP PF11559.3 KFM07380.1 - 3.9 7.3 24.0 3.3 7.5 5.9 3.4 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding zf-C4H2 PF10146.4 KFM07380.1 - 4.9 7.0 12.2 0.11 12.4 3.1 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein Fib_alpha PF08702.5 KFM07380.1 - 8 6.5 16.6 2.8 8.0 4.5 3.1 4 0 0 4 4 3 0 Fibrinogen alpha/beta chain family Rab15_effector PF15208.1 KFM07381.1 - 4.9e-75 252.0 1.0 5.5e-75 251.8 0.7 1.0 1 0 0 1 1 1 1 Rab15 effector FAD_binding_6 PF00970.19 KFM07382.1 - 1.3e-34 118.2 0.0 2e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KFM07382.1 - 4.7e-32 110.7 0.0 8.6e-32 109.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KFM07382.1 - 1.9e-06 27.8 0.0 7.5e-05 22.6 0.0 2.1 1 1 1 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KFM07382.1 - 0.027 14.4 0.0 0.079 12.9 0.0 1.8 1 1 0 1 1 1 0 Siderophore-interacting FAD-binding domain Gly_transf_sug PF04488.10 KFM07383.1 - 4.1e-22 78.5 0.0 5.6e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KFM07383.1 - 0.073 11.5 0.0 0.092 11.2 0.0 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain MNSV_P7B PF06692.6 KFM07383.1 - 0.084 12.6 0.2 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Melon necrotic spot virus P7B protein Gb3_synth PF04572.7 KFM07385.1 - 2e-47 160.2 1.9 2.8e-47 159.7 1.3 1.2 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region Gly_transf_sug PF04488.10 KFM07385.1 - 2.1e-23 82.6 0.0 5.2e-23 81.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KFM07385.1 - 0.11 10.9 0.0 0.15 10.4 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain ArfGap PF01412.13 KFM07386.1 - 2.6e-29 101.3 6.6 6.7e-29 100.0 0.9 2.7 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf FCH PF00611.18 KFM07387.1 - 7.6e-21 74.1 0.1 7.6e-21 74.1 0.1 3.7 4 0 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 KFM07387.1 - 2.4e-16 59.0 1.5 3e-16 58.7 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 KFM07387.1 - 2.2e-15 55.7 0.1 4.9e-15 54.6 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFM07387.1 - 2.8e-08 33.0 0.0 6.2e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Tweety PF04906.8 KFM07387.1 - 0.4 9.0 1.3 0.68 8.2 0.9 1.3 1 0 0 1 1 1 0 Tweety PTPlike_phytase PF14566.1 KFM07387.1 - 4.9 7.1 6.8 3.6 7.6 2.7 2.3 1 1 1 2 2 2 0 Inositol hexakisphosphate TTL PF03133.10 KFM07388.1 - 3.6e-113 377.3 0.7 4.8e-113 376.9 0.5 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 KFM07388.1 - 3.5e-06 26.0 0.1 0.0018 17.1 0.0 2.2 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.1 KFM07388.1 - 0.0034 16.5 0.0 1.7 7.6 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp bcl-2I13 PF12201.3 KFM07389.1 - 0.00092 18.7 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Bcl2-interacting killer, BH3-domain containing Bclx_interact PF08945.5 KFM07389.1 - 0.072 12.6 0.0 0.22 11.1 0.0 1.8 1 0 0 1 1 1 0 Bcl-x interacting, BH3 domain Acyl_transf_1 PF00698.16 KFM07390.1 - 1.8e-16 60.4 0.1 3.7e-16 59.3 0.1 1.3 1 1 0 1 1 1 1 Acyl transferase domain TspO_MBR PF03073.10 KFM07391.1 - 3.9e-50 169.2 12.8 4.5e-50 169.0 8.8 1.0 1 0 0 1 1 1 1 TspO/MBR family DUF1358 PF07096.6 KFM07391.1 - 0.89 9.2 5.2 0.23 11.1 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1358) TTL PF03133.10 KFM07392.1 - 8.6e-71 238.2 0.1 1.3e-70 237.7 0.1 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family FXa_inhibition PF14670.1 KFM07393.1 - 8.8e-66 217.7 177.1 6.8e-13 48.5 6.3 11.9 12 1 0 12 12 12 9 Coagulation Factor Xa inhibitory site cEGF PF12662.2 KFM07393.1 - 1.9e-39 132.9 86.0 4.1e-09 35.9 0.6 12.1 11 0 0 11 11 11 8 Complement Clr-like EGF-like GCC2_GCC3 PF07699.8 KFM07393.1 - 4.2e-30 103.0 32.4 5.6e-14 51.4 6.3 7.0 7 1 1 8 8 8 3 GCC2 and GCC3 EGF_CA PF07645.10 KFM07393.1 - 7.4e-30 102.6 171.5 1.9e-09 37.3 6.0 12.0 12 0 0 12 12 12 7 Calcium-binding EGF domain EGF PF00008.22 KFM07393.1 - 6.8e-22 77.0 132.0 1.2e-06 28.3 4.0 11.8 11 0 0 11 11 11 9 EGF-like domain EGF_3 PF12947.2 KFM07393.1 - 4.5e-21 74.5 144.3 3.3e-10 39.7 6.7 11.5 10 0 0 10 10 10 8 EGF domain CUB PF00431.15 KFM07393.1 - 5.1e-17 61.9 0.0 5.1e-17 61.9 0.0 2.5 3 0 0 3 3 3 1 CUB domain Orbi_NS3 PF01616.11 KFM07393.1 - 0.1 11.5 0.2 0.16 10.8 0.1 1.2 1 0 0 1 1 1 0 Orbivirus NS3 hEGF PF12661.2 KFM07393.1 - 3.9 7.7 52.7 0.1 12.6 0.3 10.5 9 0 0 9 9 9 0 Human growth factor-like EGF Metallophos PF00149.23 KFM07394.1 - 2.9e-12 46.4 1.5 5.1e-12 45.6 1.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KFM07394.1 - 1.9e-07 31.0 0.0 3.5e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF1880 PF08976.6 KFM07396.1 - 6.2e-05 23.0 4.4 0.00031 20.8 2.0 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF1880) EF-hand_7 PF13499.1 KFM07396.1 - 0.038 14.1 0.5 0.065 13.3 0.4 1.3 1 0 0 1 1 1 0 EF-hand domain pair Sulfotransfer_1 PF00685.22 KFM07397.1 - 8.2e-50 169.5 0.2 1.2e-49 169.0 0.1 1.3 1 1 0 1 1 1 1 Sulfotransferase domain FdsD PF11390.3 KFM07397.1 - 0.072 13.1 2.0 0.75 9.9 1.2 2.2 1 1 1 2 2 2 0 NADH-dependant formate dehydrogenase delta subunit FdsD Patatin PF01734.17 KFM07398.1 - 1.7e-06 28.0 0.0 3.2e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase CDC37_C PF08564.5 KFM07398.1 - 0.012 15.3 0.2 0.17 11.7 0.0 2.3 2 0 0 2 2 2 0 Cdc37 C terminal domain Bac_surface_Ag PF01103.18 KFM07399.1 - 8.2e-59 199.6 4.8 9.7e-59 199.4 3.4 1.0 1 0 0 1 1 1 1 Surface antigen Surf_Ag_VNR PF07244.10 KFM07399.1 - 0.0028 18.0 0.1 0.0048 17.2 0.0 1.4 1 0 0 1 1 1 1 Surface antigen variable number repeat UPF0146 PF03686.8 KFM07399.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) CH PF00307.26 KFM07400.1 - 3.9e-20 71.8 0.7 1e-10 41.6 0.3 2.3 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFM07400.1 - 0.00051 19.6 0.0 0.17 11.5 0.0 2.5 2 0 0 2 2 2 2 CAMSAP CH domain ACT PF01842.20 KFM07400.1 - 0.035 13.5 0.0 0.094 12.2 0.0 1.7 1 0 0 1 1 1 0 ACT domain CH PF00307.26 KFM07401.1 - 1e-18 67.3 1.3 3.1e-11 43.2 1.0 2.2 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFM07401.1 - 4.4e-05 23.0 0.1 0.47 10.1 0.0 2.8 3 0 0 3 3 3 2 CAMSAP CH domain Shisa PF13908.1 KFM07402.1 - 0.037 14.2 22.6 0.4 10.8 15.7 2.1 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator HbrB PF08539.6 KFM07405.1 - 2.5e-36 124.8 0.3 1.4e-34 119.2 0.2 2.2 1 1 0 1 1 1 1 HbrB-like IBN_N PF03810.14 KFM07405.1 - 0.1 12.5 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Importin-beta N-terminal domain RhoGAP PF00620.22 KFM07407.1 - 8.3e-41 139.1 0.0 1.9e-40 137.9 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.1 KFM07407.1 - 1.1e-37 129.2 3.0 1.1e-37 129.2 2.1 1.6 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 KFM07407.1 - 1.1e-12 47.6 0.3 2.4e-12 46.6 0.2 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain PHD PF00628.24 KFM07408.1 - 1.6e-08 34.1 5.8 3.5e-08 33.0 4.0 1.6 1 0 0 1 1 1 1 PHD-finger RAI1 PF08652.6 KFM07408.1 - 0.1 12.4 1.6 0.48 10.2 1.1 2.2 1 1 0 1 1 1 0 RAI1 like PD-(D/E)XK nuclease Prok-RING_1 PF14446.1 KFM07408.1 - 0.16 11.7 7.7 3.9 7.2 0.1 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 ADK_lid PF05191.9 KFM07408.1 - 5.1 6.8 8.7 1.2 8.8 2.6 2.3 2 0 0 2 2 2 0 Adenylate kinase, active site lid Ras PF00071.17 KFM07409.1 - 1.7e-33 115.2 0.1 2e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM07409.1 - 1.1e-09 38.8 0.0 1.6e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM07409.1 - 9e-08 31.5 0.1 1.1e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFM07409.1 - 0.014 14.5 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region FtsZ_C PF12327.3 KFM07409.1 - 0.035 14.1 0.0 0.058 13.4 0.0 1.3 1 0 0 1 1 1 0 FtsZ family, C-terminal domain Flt3_lig PF02947.9 KFM07409.1 - 0.054 13.3 0.1 0.078 12.8 0.1 1.3 1 0 0 1 1 1 0 flt3 ligand DUF2890 PF11081.3 KFM07410.1 - 0.3 11.1 19.9 0.24 11.4 13.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2890) Prothymosin PF03247.9 KFM07410.1 - 8.8 6.5 18.0 0.087 12.9 5.8 2.3 2 1 0 2 2 2 0 Prothymosin/parathymosin family DUF572 PF04502.8 KFM07410.1 - 8.9 5.4 23.5 10 5.2 16.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF605 PF04652.11 KFM07410.1 - 9.4 5.5 20.0 11 5.2 13.9 1.0 1 0 0 1 1 1 0 Vta1 like DUF4462 PF14692.1 KFM07411.1 - 0.047 12.9 0.3 0.079 12.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) RRM_1 PF00076.17 KFM07412.1 - 1.2e-12 47.3 0.0 2e-07 30.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM07412.1 - 3.4e-07 30.1 0.0 1.4e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) HSP20 PF00011.16 KFM07412.1 - 0.061 13.1 0.0 0.48 10.3 0.0 2.1 2 0 0 2 2 2 0 Hsp20/alpha crystallin family zf-U1 PF06220.7 KFM07412.1 - 0.065 12.7 0.3 0.18 11.3 0.2 1.7 1 0 0 1 1 1 0 U1 zinc finger zf-B_box PF00643.19 KFM07412.1 - 0.077 12.8 6.2 0.19 11.6 4.3 1.6 1 0 0 1 1 1 0 B-box zinc finger C1q PF00386.16 KFM07413.1 - 1.2e-38 131.9 0.0 1.6e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 KFM07413.1 - 8.3e-15 54.0 59.7 4.1e-08 32.6 23.3 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) PsbN PF02468.10 KFM07413.1 - 0.068 12.7 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) CC2D2AN-C2 PF15625.1 KFM07414.1 - 1.9e-41 141.3 0.0 3.6e-41 140.4 0.0 1.5 1 0 0 1 1 1 1 CC2D2A N-terminal C2 domain C2 PF00168.25 KFM07414.1 - 0.00067 19.4 0.1 0.018 14.8 0.0 2.5 2 0 0 2 2 2 1 C2 domain DUF3987 PF13148.1 KFM07414.1 - 0.0054 15.3 9.7 0.019 13.5 6.7 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3987) F-box-like PF12937.2 KFM07415.1 - 7.1e-16 57.6 0.1 2.7e-15 55.8 0.1 2.1 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 KFM07415.1 - 4.2e-13 47.8 1.4 0.032 14.2 0.0 5.1 4 0 0 4 4 4 3 Leucine Rich repeat LRR_4 PF12799.2 KFM07415.1 - 8.2e-12 44.4 3.2 4.7e-06 26.0 0.0 3.8 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) F-box PF00646.28 KFM07415.1 - 2.2e-10 39.9 1.5 7.1e-10 38.2 0.0 2.6 3 0 0 3 3 3 1 F-box domain LRR_1 PF00560.28 KFM07415.1 - 1.5e-09 36.5 2.0 0.074 13.1 0.0 5.7 5 0 0 5 5 4 3 Leucine Rich Repeat Hemerythrin PF01814.18 KFM07415.1 - 1.8e-08 34.6 0.2 3.8e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain LRR_8 PF13855.1 KFM07415.1 - 6.7e-07 28.9 1.8 0.0012 18.5 0.1 3.3 2 1 0 2 2 2 2 Leucine rich repeat LRR_7 PF13504.1 KFM07415.1 - 1.4e-06 27.5 2.8 0.73 10.2 0.0 5.5 5 0 0 5 5 4 1 Leucine rich repeat PRANC PF09372.5 KFM07415.1 - 0.017 15.0 0.0 0.076 12.9 0.0 2.2 1 0 0 1 1 1 0 PRANC domain Orthopox_A5L PF06193.6 KFM07415.1 - 0.026 14.4 2.0 0.068 13.1 1.4 1.7 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like NAAA-beta PF15508.1 KFM07415.1 - 0.8 10.0 3.5 0.46 10.8 0.3 2.2 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Rib_hydrolayse PF02267.12 KFM07416.1 - 1.7e-16 60.3 0.0 1.8e-16 60.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosyl cyclase Peptidase_A2B PF12384.3 KFM07416.1 - 0.12 11.7 0.0 0.12 11.6 0.0 1.0 1 0 0 1 1 1 0 Ty3 transposon peptidase Rib_hydrolayse PF02267.12 KFM07417.1 - 7.7e-102 339.7 0.8 9e-102 339.5 0.5 1.0 1 0 0 1 1 1 1 ADP-ribosyl cyclase DUF1628 PF07790.6 KFM07417.1 - 0.04 14.6 0.2 0.084 13.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1628) FGF-BP1 PF06473.7 KFM07418.1 - 1.6e-51 175.0 18.5 1.2e-50 172.2 12.8 1.9 1 1 0 1 1 1 1 FGF binding protein 1 (FGF-BP1) FGF-BP1 PF06473.7 KFM07419.1 - 1.2e-62 211.5 2.4 1.4e-62 211.3 1.6 1.1 1 0 0 1 1 1 1 FGF binding protein 1 (FGF-BP1) Prominin PF05478.6 KFM07420.1 - 1.3e-272 906.0 11.9 1.6e-272 905.7 8.3 1.0 1 0 0 1 1 1 1 Prominin IncA PF04156.9 KFM07420.1 - 0.03 13.9 0.1 0.03 13.9 0.1 3.2 3 0 0 3 3 3 0 IncA protein Prefoldin PF02996.12 KFM07420.1 - 0.19 11.3 3.6 11 5.6 0.1 3.4 3 0 0 3 3 3 0 Prefoldin subunit Reo_sigmaC PF04582.7 KFM07420.1 - 0.29 10.2 9.5 4.3 6.4 0.1 2.4 2 0 0 2 2 2 0 Reovirus sigma C capsid protein ATP_synt_I PF03899.10 KFM07420.1 - 0.29 11.3 0.0 0.29 11.3 0.0 3.7 3 1 0 3 3 3 0 ATP synthase I chain DUF747 PF05346.6 KFM07421.1 - 3.1e-102 342.0 17.4 4.2e-102 341.6 12.1 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family DASH_Dad4 PF08650.5 KFM07421.1 - 0.11 12.4 3.4 0.95 9.4 1.2 2.4 2 0 0 2 2 2 0 DASH complex subunit Dad4 LIM_bind PF01803.11 KFM07422.1 - 9.2e-69 231.1 2.6 9.2e-69 231.1 1.8 2.7 2 1 0 2 2 2 1 LIM-domain binding protein Vpu PF00558.14 KFM07422.1 - 0.43 10.1 1.6 5.6 6.5 0.0 2.8 3 0 0 3 3 3 0 Vpu protein Claudin_2 PF13903.1 KFM07424.1 - 4.3e-09 36.2 4.6 7.4e-09 35.5 3.2 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 KFM07424.1 - 0.0069 16.0 4.0 0.011 15.3 2.7 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_3 PF06653.6 KFM07424.1 - 0.014 15.1 12.7 0.082 12.6 8.8 2.1 1 1 0 1 1 1 0 Tight junction protein, Claudin-like Tetraspannin PF00335.15 KFM07424.1 - 3.8 6.7 10.7 5.2 6.2 7.1 1.4 1 1 0 1 1 1 0 Tetraspanin family Orbi_NS3 PF01616.11 KFM07424.1 - 8.7 5.2 6.3 3.3 6.6 0.0 2.3 2 1 1 3 3 3 0 Orbivirus NS3 Peptidase_M17 PF00883.16 KFM07425.1 - 1.6e-88 296.6 0.0 2e-88 296.2 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 KFM07425.1 - 8.9e-23 80.4 1.1 1.4e-22 79.7 0.1 1.8 2 0 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain Med28 PF11594.3 KFM07426.1 - 1.5e-43 147.3 0.6 1.7e-43 147.1 0.4 1.0 1 0 0 1 1 1 1 Mediator complex subunit 28 HTH_34 PF13601.1 KFM07426.1 - 0.0026 17.7 0.0 0.0059 16.6 0.0 1.5 1 1 0 1 1 1 1 Winged helix DNA-binding domain Filament PF00038.16 KFM07426.1 - 0.016 14.7 0.9 0.017 14.6 0.7 1.1 1 0 0 1 1 1 0 Intermediate filament protein ISG65-75 PF11727.3 KFM07426.1 - 0.063 12.3 0.1 0.083 11.9 0.0 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein Fzo_mitofusin PF04799.8 KFM07426.1 - 0.22 10.8 2.0 0.26 10.6 1.4 1.1 1 0 0 1 1 1 0 fzo-like conserved region DUF4553 PF15090.1 KFM07427.1 - 2.1e-188 627.0 35.0 2.1e-188 627.0 24.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4553) HTH_psq PF05225.11 KFM07428.1 - 5e-22 77.1 0.0 7.2e-15 54.2 0.0 2.5 2 0 0 2 2 2 2 helix-turn-helix, Psq domain LRR_8 PF13855.1 KFM07430.1 - 8e-84 275.3 78.5 6.8e-14 51.3 0.0 10.3 4 4 6 10 10 10 10 Leucine rich repeat LRR_4 PF12799.2 KFM07430.1 - 8.9e-51 168.8 43.1 6.9e-07 28.7 0.3 10.8 9 1 1 10 10 10 10 Leucine Rich repeats (2 copies) EGF PF00008.22 KFM07430.1 - 3.1e-27 94.1 92.5 4.3e-08 32.9 5.3 7.7 8 0 0 8 8 6 5 EGF-like domain LRR_1 PF00560.28 KFM07430.1 - 1.1e-25 85.7 48.6 0.14 12.3 0.0 19.3 20 0 0 20 20 20 8 Leucine Rich Repeat LRRNT PF01462.13 KFM07430.1 - 1.4e-19 68.9 45.2 3e-08 32.9 2.2 7.1 7 0 0 7 7 7 3 Leucine rich repeat N-terminal domain Laminin_G_1 PF00054.18 KFM07430.1 - 5.2e-18 65.3 0.0 9.3e-18 64.4 0.0 1.5 1 0 0 1 1 1 1 Laminin G domain Laminin_G_2 PF02210.19 KFM07430.1 - 1.8e-15 57.0 0.0 4.7e-15 55.7 0.0 1.7 2 0 0 2 2 2 1 Laminin G domain LRR_9 PF14580.1 KFM07430.1 - 8.3e-15 54.7 17.1 0.00046 19.7 0.2 5.3 4 1 1 5 5 5 5 Leucine-rich repeat LRRCT PF01463.19 KFM07430.1 - 1.9e-14 52.4 3.6 0.012 15.7 0.0 6.5 5 0 0 5 5 5 4 Leucine rich repeat C-terminal domain hEGF PF12661.2 KFM07430.1 - 4e-06 26.5 56.7 0.033 14.2 1.6 8.0 8 0 0 8 8 6 5 Human growth factor-like EGF EGF_CA PF07645.10 KFM07430.1 - 0.00052 19.9 5.7 0.00052 19.9 3.9 8.1 7 1 2 9 9 7 3 Calcium-binding EGF domain FXa_inhibition PF14670.1 KFM07430.1 - 0.00065 19.7 4.1 0.00065 19.7 2.9 7.0 4 2 2 6 6 5 3 Coagulation Factor Xa inhibitory site LRR_6 PF13516.1 KFM07430.1 - 0.073 13.1 0.0 0.16 12.0 0.0 15.5 15 4 4 19 19 16 0 Leucine Rich repeat ParcG PF10274.4 KFM07431.1 - 2e-47 161.4 0.0 2.6e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein TAFH PF07531.9 KFM07431.1 - 0.11 12.1 0.7 2.6 7.7 0.0 2.3 1 1 1 2 2 2 0 NHR1 homology to TAF PTS_EIIA_2 PF00359.17 KFM07431.1 - 0.13 11.9 0.1 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 EF-hand_7 PF13499.1 KFM07432.1 - 5.4e-23 80.8 1.2 9.5e-16 57.7 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KFM07432.1 - 3.5e-22 75.9 10.5 3e-08 32.3 0.2 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 KFM07432.1 - 4.4e-19 66.6 6.7 3.6e-06 26.4 0.1 4.3 4 1 1 5 5 5 3 EF-hand domain EF-hand_5 PF13202.1 KFM07432.1 - 1.8e-16 58.6 5.3 4.1e-05 22.7 0.4 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 KFM07432.1 - 6.1e-16 57.7 9.7 9.1e-07 28.3 0.2 4.5 2 1 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFM07432.1 - 1.6e-08 34.5 1.8 1.1e-05 25.3 0.2 3.2 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFM07432.1 - 0.00011 21.8 2.6 0.0065 16.1 0.2 2.9 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KFM07432.1 - 0.00049 19.9 0.5 1.6 8.7 0.0 3.9 2 1 1 3 3 3 2 EF-hand domain EF-hand_2 PF09068.6 KFM07432.1 - 0.0065 16.5 0.1 1.9 8.5 0.0 2.7 2 1 1 3 3 3 1 EF hand S10_plectin PF03501.10 KFM07432.1 - 0.0099 15.7 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Plectin/S10 domain OSTMP1 PF09777.4 KFM07433.1 - 7.4e-76 254.4 8.3 8.3e-76 254.2 5.8 1.0 1 0 0 1 1 1 1 Osteopetrosis-associated transmembrane protein 1 precursor CECR6_TMEM121 PF14997.1 KFM07433.1 - 0.00057 19.5 0.1 0.0008 19.0 0.0 1.3 1 0 0 1 1 1 1 CECR6/TMEM121 family FUR PF01475.14 KFM07433.1 - 0.076 12.9 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Ferric uptake regulator family DUF1240 PF06836.7 KFM07433.1 - 0.088 13.0 1.0 0.69 10.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) PX PF00787.19 KFM07434.1 - 5.2e-22 77.7 0.2 5.7e-22 77.6 0.1 1.1 1 0 0 1 1 1 1 PX domain RdRP_1 PF00680.15 KFM07434.1 - 0.038 12.2 0.0 0.045 11.9 0.0 1.0 1 0 0 1 1 1 0 RNA dependent RNA polymerase AFG1_ATPase PF03969.11 KFM07435.1 - 8.8e-111 370.1 1.6 2.9e-106 355.3 0.3 2.0 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 KFM07435.1 - 2.4e-05 24.3 0.1 0.0068 16.4 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA PF00004.24 KFM07435.1 - 0.00011 22.3 0.1 0.00096 19.3 0.0 2.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.13 KFM07435.1 - 0.00089 18.9 3.6 0.39 10.3 0.4 3.4 3 1 0 3 3 3 2 Bacterial dnaA protein UvrD-helicase PF00580.16 KFM07435.1 - 0.0026 17.0 0.1 0.021 14.1 0.0 2.1 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 KFM07435.1 - 0.0034 17.5 0.1 0.02 15.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 KFM07435.1 - 0.0061 16.2 0.0 0.033 13.8 0.0 2.1 2 0 0 2 2 2 1 NACHT domain Arch_ATPase PF01637.13 KFM07435.1 - 0.026 14.2 0.4 0.15 11.7 0.1 2.3 2 1 0 2 2 2 0 Archaeal ATPase PIF1 PF05970.9 KFM07435.1 - 0.082 11.8 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase DUF1586 PF07625.6 KFM07435.1 - 0.083 12.6 0.3 0.14 11.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1586) RRM_1 PF00076.17 KFM07436.1 - 1.4e-40 136.7 0.0 2.4e-20 71.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM07436.1 - 7.2e-26 89.9 0.0 9e-12 44.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM07436.1 - 1.6e-20 72.6 0.0 4.3e-09 36.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KFM07436.1 - 0.0021 17.7 0.1 0.45 10.3 0.0 2.2 2 0 0 2 2 2 2 Limkain b1 OB_RNB PF08206.6 KFM07436.1 - 0.0065 15.9 0.1 0.22 11.0 0.0 2.4 2 0 0 2 2 2 1 Ribonuclease B OB domain Sugar_tr PF00083.19 KFM07437.1 - 9.5e-23 80.4 14.2 7.3e-17 61.0 1.4 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KFM07437.1 - 1.3e-18 66.8 23.9 2.9e-11 42.6 4.0 2.4 3 0 0 3 3 3 2 Major Facilitator Superfamily Pentapeptide_4 PF13599.1 KFM07437.1 - 5.4e-11 42.1 10.3 9.7e-11 41.3 7.1 1.3 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) MFS_3 PF05977.8 KFM07437.1 - 0.0047 15.0 0.1 0.0067 14.5 0.1 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector RGM_N PF06535.7 KFM07438.1 - 1.8e-63 213.3 0.7 3.1e-63 212.5 0.5 1.4 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) N-terminus RGM_C PF06534.8 KFM07438.1 - 1.2e-62 210.3 0.1 2.1e-62 209.4 0.1 1.4 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) C-terminus 7tm_1 PF00001.16 KFM07439.1 - 3.1e-42 144.5 8.0 3.6e-41 141.0 5.6 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) ABC2_membrane PF01061.19 KFM07439.1 - 0.048 12.8 0.1 0.048 12.8 0.0 3.1 3 0 0 3 3 3 0 ABC-2 type transporter LIX1 PF14954.1 KFM07440.1 - 1.5e-102 341.9 0.3 1.7e-102 341.7 0.2 1.0 1 0 0 1 1 1 1 Limb expression 1 dsrm PF00035.20 KFM07440.1 - 0.084 13.4 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 Double-stranded RNA binding motif DND1_DSRM PF14709.1 KFM07440.1 - 0.1 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 zf-RING_2 PF13639.1 KFM07441.1 - 2.7e-14 52.6 6.2 3.9e-14 52.1 4.3 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KFM07441.1 - 4.8e-08 32.5 3.4 7.6e-08 31.9 2.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFM07441.1 - 1.8e-07 31.0 2.4 4.4e-07 29.8 1.7 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM07441.1 - 8.6e-07 28.5 2.0 1.6e-06 27.6 1.4 1.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM07441.1 - 9.6e-07 28.3 3.8 1.7e-06 27.6 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFM07441.1 - 1.5e-05 25.0 6.5 8.2e-05 22.6 4.8 2.1 1 1 1 2 2 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KFM07441.1 - 0.0001 22.0 2.9 0.00031 20.5 2.0 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Rad50_zn_hook PF04423.9 KFM07441.1 - 0.0015 17.9 3.1 0.028 13.8 0.2 2.4 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-RING_UBOX PF13445.1 KFM07441.1 - 0.0029 17.2 5.0 0.017 14.8 0.9 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-HC5HC2H PF13771.1 KFM07441.1 - 0.0062 16.6 0.3 0.019 15.0 0.0 1.7 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 KFM07441.1 - 0.0073 16.2 0.6 0.012 15.5 0.1 1.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-RING_4 PF14570.1 KFM07441.1 - 0.029 13.9 3.3 0.81 9.3 0.0 2.4 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-H2C2_2 PF13465.1 KFM07441.1 - 0.078 13.3 0.5 20 5.7 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger double domain zf-Di19 PF05605.7 KFM07441.1 - 0.086 12.9 5.1 1.4 9.0 1.3 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Baculo_IE-1 PF05290.6 KFM07441.1 - 0.11 12.2 2.6 0.17 11.6 1.8 1.3 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Prok-RING_1 PF14446.1 KFM07441.1 - 0.11 12.2 4.4 5.1 6.9 0.1 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C2H2_2 PF12756.2 KFM07441.1 - 0.11 12.5 0.3 0.78 9.8 0.0 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-Nse PF11789.3 KFM07441.1 - 0.12 11.8 3.0 0.27 10.8 2.1 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Opy2 PF09463.5 KFM07441.1 - 0.14 12.2 2.3 3.6 7.7 0.2 2.3 2 0 0 2 2 2 0 Opy2 protein FANCL_C PF11793.3 KFM07441.1 - 0.24 11.3 8.5 2.7 8.0 5.9 2.4 1 1 1 2 2 2 0 FANCL C-terminal domain Vps39_2 PF10367.4 KFM07441.1 - 0.51 10.5 3.0 5.2 7.2 0.6 2.1 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 DUF329 PF03884.9 KFM07441.1 - 0.63 9.6 3.3 11 5.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF329) PHD PF00628.24 KFM07441.1 - 1.1 8.9 4.3 2.2 8.0 1.0 2.3 2 1 0 2 2 2 0 PHD-finger zf-C3HC4_4 PF15227.1 KFM07441.1 - 1.8 8.5 7.4 37 4.2 0.2 2.9 1 1 2 3 3 3 0 zinc finger of C3HC4-type, RING OrfB_Zn_ribbon PF07282.6 KFM07441.1 - 2.5 7.8 4.5 2.8 7.6 0.4 2.1 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-RING_6 PF14835.1 KFM07441.1 - 2.7 7.8 6.1 51 3.7 4.3 2.6 1 1 0 1 1 1 0 zf-RING of BARD1-type protein HTH_9 PF08221.6 KFM07442.1 - 2.8e-07 30.2 0.9 5e-07 29.4 0.5 1.5 1 1 1 2 2 2 1 RNA polymerase III subunit RPC82 helix-turn-helix domain LLGL PF08366.8 KFM07442.1 - 0.068 13.0 0.0 0.11 12.3 0.0 1.4 2 0 0 2 2 2 0 LLGL2 PINIT PF14324.1 KFM07443.1 - 2.2e-43 147.7 0.2 3.6e-43 147.1 0.2 1.3 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 KFM07443.1 - 9.1e-21 73.1 5.3 1.9e-20 72.1 3.7 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 KFM07443.1 - 0.00022 20.6 1.8 0.0005 19.5 1.3 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.22 KFM07443.1 - 0.00073 18.9 0.1 0.0017 17.7 0.1 1.7 1 0 0 1 1 1 1 SAP domain PHD PF00628.24 KFM07443.1 - 5.4 6.7 8.4 0.25 11.0 1.4 2.0 2 0 0 2 2 2 0 PHD-finger UAA PF08449.6 KFM07446.1 - 1e-96 323.4 24.6 1.2e-96 323.1 17.0 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 KFM07446.1 - 0.0014 18.6 12.5 0.0014 18.6 8.7 3.1 2 1 0 3 3 3 2 EamA-like transporter family GST_C PF00043.20 KFM07447.1 - 3.2e-07 30.2 0.0 5.9e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFM07447.1 - 2.5e-06 27.8 0.1 3.4e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFM07447.1 - 6.7e-06 25.8 0.0 1.1e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Muted PF14942.1 KFM07448.1 - 1.3e-57 193.7 17.0 1.5e-57 193.5 11.8 1.0 1 0 0 1 1 1 1 Organelle biogenesis, Muted-like protein OmpH PF03938.9 KFM07448.1 - 0.029 14.3 10.3 0.039 13.8 7.1 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF802 PF05650.6 KFM07448.1 - 0.066 13.3 0.7 0.11 12.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF802) GSH-S_N PF02951.9 KFM07448.1 - 0.082 12.7 2.8 0.13 12.1 1.9 1.3 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, N-terminal domain Cut8_C PF08559.5 KFM07448.1 - 0.13 12.0 3.2 0.16 11.7 2.2 1.1 1 0 0 1 1 1 0 Cut8 six-helix bundle DUF445 PF04286.7 KFM07448.1 - 0.18 11.3 7.3 0.2 11.1 5.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF148 PF02520.12 KFM07448.1 - 0.25 11.1 6.4 0.37 10.6 3.1 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF148 FliD_C PF07195.7 KFM07448.1 - 0.44 9.8 7.1 1.3 8.2 5.0 1.8 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF3829 PF12889.2 KFM07448.1 - 0.67 9.0 12.9 1 8.5 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) Ax_dynein_light PF10211.4 KFM07448.1 - 1.2 8.9 15.3 1.6 8.5 10.6 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain Rota_NSP4 PF01452.11 KFM07448.1 - 4.5 6.5 6.1 9.6 5.5 4.2 1.6 1 1 0 1 1 1 0 Rotavirus non structural protein AAA_23 PF13476.1 KFM07448.1 - 5.6 7.2 7.1 8.2 6.6 5.0 1.2 1 0 0 1 1 1 0 AAA domain UMPH-1 PF05822.7 KFM07448.1 - 5.8 6.1 9.0 15 4.8 5.9 1.8 1 1 1 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) Exonuc_VII_L PF02601.10 KFM07448.1 - 8.1 5.5 9.3 9.9 5.2 6.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4094 PF13334.1 KFM07448.1 - 9.1 6.7 7.5 14 6.1 5.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) Thioredoxin PF00085.15 KFM07449.1 - 3.2e-83 274.1 0.1 1.7e-30 104.7 0.0 3.0 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_2 PF13098.1 KFM07449.1 - 7.9e-16 58.2 3.8 0.0013 18.8 0.0 5.3 3 3 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KFM07449.1 - 5.1e-12 45.7 1.9 0.02 15.0 0.0 5.2 3 3 3 6 6 6 3 Thioredoxin-like Thioredoxin_7 PF13899.1 KFM07449.1 - 6.7e-07 29.2 1.7 0.53 10.3 0.0 3.5 3 0 0 3 3 3 3 Thioredoxin-like HyaE PF07449.6 KFM07449.1 - 1.3e-05 25.0 0.0 0.031 14.1 0.0 3.1 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.1 KFM07449.1 - 5.5e-05 22.9 0.0 2.3 8.0 0.0 3.6 3 0 0 3 3 3 2 Thioredoxin domain TraF PF13728.1 KFM07449.1 - 0.00015 21.2 0.0 1.7 8.0 0.0 3.6 3 2 0 3 3 3 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.1 KFM07449.1 - 0.001 18.6 0.2 1.5 8.3 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_4 PF13462.1 KFM07449.1 - 0.0021 18.0 0.4 19 5.1 0.0 4.5 3 2 2 5 5 5 0 Thioredoxin AhpC-TSA PF00578.16 KFM07449.1 - 0.0025 17.5 1.6 1.6 8.4 0.0 2.9 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.5 KFM07449.1 - 0.0035 16.8 1.9 1.6 8.2 0.0 2.6 3 0 0 3 3 3 2 Redoxin Mu-like_Com PF10122.4 KFM07449.1 - 0.61 9.1 8.5 3.5 6.7 1.1 3.3 3 0 0 3 3 3 0 Mu-like prophage protein Com TGF_beta PF00019.15 KFM07450.1 - 1.6e-44 150.4 1.7 3.5e-44 149.3 1.2 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.13 KFM07450.1 - 2.9e-40 138.0 0.7 3.7e-40 137.7 0.0 1.5 2 0 0 2 2 2 1 TGF-beta propeptide YafO_toxin PF13957.1 KFM07450.1 - 0.028 14.2 0.2 0.24 11.2 0.0 2.4 3 0 0 3 3 3 0 Toxin YafO, type II toxin-antitoxin system Plectin PF00681.15 KFM07451.1 - 1.3e-138 450.3 17.0 2.3e-18 65.4 0.1 16.0 14 3 3 17 17 17 13 Plectin repeat Reo_sigmaC PF04582.7 KFM07451.1 - 4.7 6.2 43.2 0.16 11.1 0.3 7.3 4 1 3 9 9 9 0 Reovirus sigma C capsid protein RIO1 PF01163.17 KFM07452.1 - 1.9e-76 255.6 0.8 5.2e-76 254.2 0.5 1.8 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.20 KFM07452.1 - 1.1e-06 28.0 0.1 3.4e-06 26.3 0.1 1.9 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KFM07452.1 - 0.00026 20.7 0.0 0.0049 16.6 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KFM07452.1 - 0.0017 17.4 0.4 0.024 13.7 0.2 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TRAP_alpha PF03896.11 KFM07453.1 - 1.4e-134 447.5 1.1 1.6e-134 447.3 0.8 1.0 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DUF2890 PF11081.3 KFM07453.1 - 5.7 6.9 8.6 11 5.9 6.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) zf-C2H2 PF00096.21 KFM07454.1 - 2.4e-42 140.7 120.8 8.4e-05 22.6 1.7 16.0 16 0 0 16 16 16 14 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM07454.1 - 9.8e-36 120.3 111.3 3.5e-08 33.3 0.9 19.9 20 0 0 20 20 20 8 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM07454.1 - 7.9e-30 100.9 114.7 2.9e-05 24.0 0.3 15.8 16 0 0 16 16 16 12 C2H2-type zinc finger zf-met PF12874.2 KFM07454.1 - 1.7e-11 43.9 77.2 0.011 15.9 0.3 13.4 13 0 0 13 13 13 8 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFM07454.1 - 2.3e-09 37.0 66.5 0.072 13.2 1.1 14.0 15 0 0 15 15 15 7 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 KFM07454.1 - 2.3e-05 24.3 3.3 0.0021 18.1 0.0 12.6 15 0 0 15 15 15 3 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 KFM07454.1 - 0.00028 20.6 0.1 0.00028 20.6 0.1 13.4 16 0 0 16 16 16 5 C2H2-type zinc finger BolA PF01722.13 KFM07454.1 - 0.026 14.4 2.1 7.4 6.6 0.2 4.4 4 1 1 5 5 5 0 BolA-like protein E1_DerP2_DerF2 PF02221.10 KFM07456.1 - 8.4e-14 51.9 0.7 1.9e-13 50.7 0.5 1.6 1 1 1 2 2 2 1 ML domain Transglut_C PF00927.17 KFM07457.1 - 3.8e-43 145.8 0.8 2.9e-20 72.2 0.0 2.4 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_N PF00868.15 KFM07457.1 - 9.9e-37 125.6 0.1 5.3e-35 120.0 0.0 3.0 2 1 2 4 4 4 1 Transglutaminase family Transglut_core PF01841.14 KFM07457.1 - 2.5e-17 63.1 0.3 5.4e-17 62.0 0.2 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF11 PF01345.13 KFM07457.1 - 0.11 12.5 2.8 1.2 9.1 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF11 NRN1 PF15056.1 KFM07459.1 - 1.6e-25 88.8 0.4 1.9e-25 88.6 0.3 1.1 1 0 0 1 1 1 1 Neuritin protein family tRNA-synt_2d PF01409.15 KFM07460.1 - 6.9e-50 169.5 1.8 2.8e-31 108.5 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 KFM07460.1 - 2.3e-22 78.9 0.0 8.3e-22 77.1 0.0 2.0 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.15 KFM07460.1 - 0.023 13.5 0.1 2.1 7.0 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) Complex1_LYR_1 PF13232.1 KFM07461.1 - 7.5e-12 45.2 1.7 8e-12 45.1 1.2 1.0 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KFM07461.1 - 1.8e-11 43.6 2.0 1.9e-11 43.5 1.4 1.0 1 0 0 1 1 1 1 Complex 1 protein (LYR family) EntA_Immun PF08951.5 KFM07461.1 - 0.0052 16.9 0.6 0.0059 16.7 0.4 1.0 1 0 0 1 1 1 1 Enterocin A Immunity cwf21 PF08312.7 KFM07461.1 - 0.039 13.8 0.5 0.046 13.5 0.3 1.1 1 0 0 1 1 1 0 cwf21 domain Ribonuc_P_40 PF08584.6 KFM07462.1 - 1.7e-96 322.5 0.0 2e-96 322.3 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit ECH PF00378.15 KFM07463.1 - 1.3e-35 122.7 1.1 1.6e-35 122.3 0.0 1.7 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family Chromo PF00385.19 KFM07463.1 - 1.1e-18 66.6 3.3 2.2e-18 65.6 2.3 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 KFM07463.1 - 0.021 14.5 0.9 0.021 14.5 0.6 2.5 3 0 0 3 3 3 0 RNA binding activity-knot of a chromodomain PWWP PF00855.12 KFM07463.1 - 0.5 10.6 3.3 1.8 8.7 1.9 2.3 2 1 0 2 2 2 0 PWWP domain ECH PF00378.15 KFM07464.1 - 1.3e-42 145.6 0.1 2.2e-42 144.8 0.0 1.4 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family ACBP PF00887.14 KFM07464.1 - 3.7e-30 103.4 0.4 7e-30 102.5 0.3 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein LamB_YcsF PF03746.11 KFM07464.1 - 0.04 13.0 0.0 0.066 12.3 0.0 1.2 1 0 0 1 1 1 0 LamB/YcsF family NYN PF01936.13 KFM07464.1 - 0.089 13.0 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 NYN domain TPR_21 PF09976.4 KFM07464.1 - 0.11 12.4 1.9 0.62 9.9 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.20 KFM07465.1 - 2.3e-48 164.6 0.6 2.3e-48 164.6 0.4 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM07465.1 - 1.1e-22 80.3 0.1 3.8e-22 78.5 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KFM07465.1 - 0.0022 16.8 0.5 0.0044 15.8 0.2 1.5 1 1 0 1 1 1 1 Poxvirus serine/threonine protein kinase PX PF00787.19 KFM07466.1 - 0.087 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 PX domain Sugar_tr PF00083.19 KFM07467.1 - 1.4e-23 83.1 18.4 2e-23 82.7 12.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFM07467.1 - 3.1e-17 62.3 21.7 2.5e-15 56.0 16.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 KFM07467.1 - 0.027 12.5 2.9 0.057 11.5 2.0 1.4 1 0 0 1 1 1 0 Transmembrane secretion effector Rieske PF00355.21 KFM07467.1 - 0.1 12.2 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain RepB-RCR_reg PF10723.4 KFM07468.1 - 0.047 13.4 0.0 0.051 13.3 0.0 1.1 1 0 0 1 1 1 0 Replication regulatory protein RepB Tubulin PF00091.20 KFM07469.1 - 2.6e-59 200.6 0.0 3.9e-59 200.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFM07469.1 - 7.7e-51 171.3 0.1 1.3e-50 170.7 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KFM07469.1 - 0.019 14.4 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain Tubulin PF00091.20 KFM07471.1 - 3.2e-60 203.6 0.0 5e-60 203.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFM07471.1 - 7.6e-51 171.4 0.1 1.2e-50 170.7 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KFM07471.1 - 0.02 14.3 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain Abhydrolase_6 PF12697.2 KFM07473.1 - 6e-30 104.8 0.0 6.9e-30 104.6 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFM07473.1 - 3.8e-19 69.1 0.0 4.3e-13 49.3 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFM07473.1 - 2.7e-17 62.8 0.0 7.9e-17 61.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KFM07473.1 - 0.00016 21.0 0.0 0.0031 16.8 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 KFM07473.1 - 0.00067 19.1 0.0 0.1 12.0 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 KFM07473.1 - 0.00079 18.7 0.0 0.0063 15.7 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.8 KFM07473.1 - 0.0023 17.4 0.1 0.012 15.0 0.0 2.3 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.3 KFM07473.1 - 0.0027 17.5 0.0 0.0054 16.5 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase BAAT_C PF08840.6 KFM07473.1 - 0.0029 17.3 0.0 0.0046 16.6 0.0 1.3 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal LIP PF03583.9 KFM07473.1 - 0.05 12.7 0.1 1.9 7.5 0.0 2.2 2 0 0 2 2 2 0 Secretory lipase Esterase PF00756.15 KFM07473.1 - 0.051 12.9 0.2 0.22 10.9 0.0 1.8 1 1 1 2 2 2 0 Putative esterase KH_dom-like PF14714.1 KFM07473.1 - 0.064 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal Pkinase PF00069.20 KFM07474.1 - 2.4e-52 177.6 0.1 4.3e-52 176.8 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM07474.1 - 4e-52 176.8 0.1 5.6e-52 176.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Death PF00531.17 KFM07474.1 - 2.4e-20 72.0 1.1 3.8e-19 68.2 0.2 2.6 2 0 0 2 2 2 1 Death domain RHIM PF12721.2 KFM07474.1 - 6.2e-13 48.9 2.9 6.2e-13 48.9 2.0 3.0 3 0 0 3 3 3 1 RIP homotypic interaction motif Kinase-like PF14531.1 KFM07474.1 - 0.00034 19.6 0.0 0.00054 19.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KFM07474.1 - 0.003 16.9 0.1 0.0057 16.0 0.1 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KFM07474.1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Flavodoxin_2 PF02525.12 KFM07475.1 - 2.5e-51 174.0 0.0 3e-51 173.7 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.10 KFM07475.1 - 2e-13 50.1 0.0 3.8e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.2 KFM07475.1 - 0.01 15.2 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin DSPc PF00782.15 KFM07476.1 - 2.3e-33 114.6 0.1 3.2e-32 110.9 0.0 2.0 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFM07476.1 - 0.00011 21.6 0.3 0.00018 20.9 0.1 1.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KFM07476.1 - 0.02 14.9 0.4 0.13 12.2 0.0 2.1 2 1 0 2 2 2 0 Inositol hexakisphosphate Paramyxo_PNT PF13825.1 KFM07476.1 - 0.031 13.5 0.0 0.065 12.4 0.0 1.5 2 0 0 2 2 2 0 Paramyxovirus structural protein V/P N-terminus IRF-3 PF10401.4 KFM07477.1 - 3.6e-62 209.1 0.3 4.9e-62 208.7 0.2 1.2 1 0 0 1 1 1 1 Interferon-regulatory factor 3 IRF PF00605.12 KFM07477.1 - 4.4e-46 155.2 0.2 6.9e-46 154.5 0.1 1.3 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor Sec5 PF15469.1 KFM07478.1 - 3.7e-56 189.7 0.4 1e-55 188.2 0.1 2.0 2 0 0 2 2 2 1 Exocyst complex component Sec5 TIG PF01833.19 KFM07478.1 - 4.4e-08 33.0 0.4 9.2e-08 31.9 0.3 1.6 1 0 0 1 1 1 1 IPT/TIG domain SAM_2 PF07647.12 KFM07478.1 - 0.035 13.9 0.1 0.14 12.0 0.0 2.0 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF4618 PF15397.1 KFM07478.1 - 0.046 13.0 2.2 0.89 8.8 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Epimerase PF01370.16 KFM07479.1 - 3.2e-64 216.5 0.0 3.8e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KFM07479.1 - 4.6e-06 25.7 0.0 6.2e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain MgsA_C PF12002.3 KFM07481.1 - 4.8e-60 202.0 0.0 2.6e-59 199.6 0.0 1.9 2 0 0 2 2 2 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 KFM07481.1 - 2.3e-09 37.5 0.4 4.2e-09 36.6 0.3 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KFM07481.1 - 3.9e-07 29.3 0.4 0.00045 19.3 0.1 2.2 1 1 1 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus Sigma54_activat PF00158.21 KFM07481.1 - 0.004 16.6 0.1 0.012 15.0 0.0 1.8 2 0 0 2 2 2 1 Sigma-54 interaction domain DNA_pol3_delta2 PF13177.1 KFM07481.1 - 0.015 14.9 0.3 0.026 14.1 0.2 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_14 PF13173.1 KFM07481.1 - 0.029 14.2 0.0 0.063 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Serpin PF00079.15 KFM07482.1 - 5.5e-132 440.3 0.1 6.3e-132 440.2 0.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.15 KFM07483.1 - 9.1e-135 449.5 0.1 1e-134 449.3 0.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.15 KFM07484.1 - 4.8e-134 447.1 7.7 5.4e-134 447.0 5.3 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.15 KFM07485.1 - 4.4e-130 434.1 5.0 5e-130 433.9 3.5 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.15 KFM07486.1 - 1.7e-128 428.9 2.5 1.9e-128 428.7 1.7 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.15 KFM07487.1 - 4e-77 259.8 0.4 4.4e-77 259.7 0.3 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF3900 PF13039.1 KFM07487.1 - 0.053 13.0 0.0 0.16 11.5 0.0 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3900) Thioredoxin_8 PF13905.1 KFM07487.1 - 0.084 12.9 0.1 0.23 11.6 0.1 1.7 1 0 0 1 1 1 0 Thioredoxin-like Sec-ASP3 PF15432.1 KFM07487.1 - 0.11 12.4 0.4 1.4 8.8 0.0 2.1 2 0 0 2 2 2 0 Accessory Sec secretory system ASP3 Serpin PF00079.15 KFM07488.1 - 1.8e-78 264.3 0.2 2e-78 264.1 0.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) MTS_N PF08468.6 KFM07488.1 - 0.11 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain N-terminal Serpin PF00079.15 KFM07489.1 - 8.1e-79 265.4 0.1 9e-79 265.2 0.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) MTS_N PF08468.6 KFM07489.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain N-terminal Serpin PF00079.15 KFM07490.1 - 5e-126 420.7 0.8 5.6e-126 420.6 0.5 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.15 KFM07491.1 - 1.1e-100 337.3 5.6 1.2e-100 337.2 3.9 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) GETHR PF05671.6 KFM07492.1 - 0.54 9.4 56.9 7.7 5.7 5.0 3.5 1 1 2 3 3 3 0 GETHR pentapeptide repeat (5 copies) AAA PF00004.24 KFM07493.1 - 1.1e-31 109.7 0.0 1.4e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFM07493.1 - 3.8e-07 30.3 0.1 8.6e-05 22.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KFM07493.1 - 1.1e-06 28.1 0.2 0.024 14.0 0.0 2.1 1 1 1 2 2 2 2 AAA domain IstB_IS21 PF01695.12 KFM07493.1 - 2e-06 27.3 0.0 2.6e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 KFM07493.1 - 2.5e-06 26.4 0.0 3.2e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 KFM07493.1 - 4.9e-06 27.3 0.0 7.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KFM07493.1 - 6.3e-06 26.1 0.0 8.8e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KFM07493.1 - 1.1e-05 24.5 0.0 1.2e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KFM07493.1 - 1.2e-05 25.1 0.0 2.6e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KFM07493.1 - 1.8e-05 24.8 0.0 0.00051 20.0 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 KFM07493.1 - 0.00011 21.1 0.0 0.00014 20.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 KFM07493.1 - 0.00019 21.3 0.0 0.00026 20.8 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KFM07493.1 - 0.0002 21.3 0.0 0.0003 20.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 KFM07493.1 - 0.00056 20.2 0.0 0.00087 19.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 KFM07493.1 - 0.00097 18.8 0.0 0.037 13.7 0.0 2.1 1 1 0 1 1 1 1 NACHT domain KaiC PF06745.8 KFM07493.1 - 0.0011 18.0 0.1 0.47 9.5 0.0 2.1 1 1 1 2 2 2 2 KaiC RNA_helicase PF00910.17 KFM07493.1 - 0.002 18.2 0.0 0.003 17.7 0.0 1.3 1 1 0 1 1 1 1 RNA helicase ResIII PF04851.10 KFM07493.1 - 0.0026 17.5 0.0 0.0032 17.3 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Zeta_toxin PF06414.7 KFM07493.1 - 0.0027 16.8 0.1 0.035 13.2 0.0 2.1 1 1 1 2 2 2 1 Zeta toxin Arch_ATPase PF01637.13 KFM07493.1 - 0.0038 16.9 0.0 0.23 11.1 0.0 2.0 1 1 1 2 2 2 1 Archaeal ATPase PhoH PF02562.11 KFM07493.1 - 0.0039 16.4 0.0 0.0085 15.3 0.0 1.6 2 0 0 2 2 1 1 PhoH-like protein Mg_chelatase PF01078.16 KFM07493.1 - 0.005 16.0 0.1 0.011 14.9 0.0 1.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KFM07493.1 - 0.0085 15.5 0.0 0.042 13.3 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 KFM07493.1 - 0.01 15.8 0.0 0.019 14.9 0.0 1.4 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.1 KFM07493.1 - 0.01 15.5 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain KAP_NTPase PF07693.9 KFM07493.1 - 0.014 14.4 0.1 0.96 8.3 0.0 2.1 1 1 1 2 2 2 0 KAP family P-loop domain AAA_21 PF13304.1 KFM07493.1 - 0.016 15.2 1.0 1.8 8.4 0.0 2.1 1 1 1 2 2 2 0 AAA domain NB-ARC PF00931.17 KFM07493.1 - 0.018 13.8 0.0 0.023 13.5 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain Guanylate_kin PF00625.16 KFM07493.1 - 0.019 14.4 0.0 0.054 12.9 0.0 1.7 1 1 0 2 2 2 0 Guanylate kinase MCM PF00493.18 KFM07493.1 - 0.022 13.5 0.0 0.036 12.8 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family AAA_28 PF13521.1 KFM07493.1 - 0.025 14.5 0.0 0.038 13.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KFM07493.1 - 0.037 13.7 0.0 3.2 7.4 0.0 2.1 2 0 0 2 2 2 0 NTPase Torsin PF06309.6 KFM07493.1 - 0.041 13.7 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 Torsin AAA_24 PF13479.1 KFM07493.1 - 0.048 13.2 0.1 0.071 12.6 0.1 1.4 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 KFM07493.1 - 0.049 13.1 0.0 0.066 12.7 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Parvo_NS1 PF01057.12 KFM07493.1 - 0.055 12.3 0.0 0.077 11.8 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.22 KFM07493.1 - 0.078 13.2 0.0 0.12 12.6 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_30 PF13604.1 KFM07493.1 - 0.094 12.2 0.0 0.14 11.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.5 KFM07493.1 - 0.1 11.7 0.1 0.24 10.5 0.0 1.7 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_10 PF12846.2 KFM07493.1 - 0.11 11.9 0.1 0.44 9.9 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain MMR_HSR1 PF01926.18 KFM07493.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.6 2 0 0 2 2 1 0 50S ribosome-binding GTPase DUF2075 PF09848.4 KFM07493.1 - 0.14 11.0 0.0 0.2 10.5 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Vps4_C PF09336.5 KFM07494.1 - 5e-30 103.1 0.2 1e-29 102.1 0.2 1.5 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA PF00004.24 KFM07494.1 - 0.00016 21.8 0.0 0.00034 20.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) adh_short PF00106.20 KFM07495.1 - 3.9e-30 104.9 0.0 5.1e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFM07495.1 - 1.8e-13 50.5 0.0 2.5e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFM07495.1 - 7.4e-12 45.5 0.0 1.1e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Saccharop_dh PF03435.13 KFM07495.1 - 0.0016 17.4 0.1 0.0027 16.7 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 KFM07495.1 - 0.0034 17.4 0.1 0.078 12.9 0.0 2.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFM07495.1 - 0.071 12.5 0.2 0.14 11.5 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 KFM07495.1 - 0.096 11.7 0.0 0.19 10.8 0.0 1.5 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) ApbA PF02558.11 KFM07495.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MARVEL PF01284.18 KFM07496.1 - 0.0015 18.3 3.1 0.0022 17.8 2.2 1.3 1 0 0 1 1 1 1 Membrane-associating domain Claudin_2 PF13903.1 KFM07496.1 - 0.61 9.7 4.4 1.6 8.4 3.1 1.8 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction LRR_4 PF12799.2 KFM07497.1 - 1.8e-39 132.7 39.0 8.3e-05 22.1 0.0 12.1 6 4 4 11 11 11 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM07497.1 - 7.3e-37 124.9 50.0 7.6e-07 28.7 1.1 10.1 3 2 11 14 14 14 14 Leucine rich repeat PP2C PF00481.16 KFM07497.1 - 5.9e-34 117.6 0.0 9.2e-34 116.9 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_1 PF00560.28 KFM07497.1 - 3.2e-26 87.3 53.0 0.16 12.0 0.3 19.8 18 1 2 20 20 20 11 Leucine Rich Repeat LRR_7 PF13504.1 KFM07497.1 - 8e-08 31.2 55.2 1.4 9.4 0.3 17.4 19 0 0 19 19 19 3 Leucine rich repeat LRR_6 PF13516.1 KFM07497.1 - 2.2e-05 24.0 40.4 0.098 12.7 1.1 14.0 14 3 2 16 16 16 2 Leucine Rich repeat zf-CCHC PF00098.18 KFM07498.1 - 1.8e-05 24.4 1.6 4.5e-05 23.1 1.1 1.8 1 0 0 1 1 1 1 Zinc knuckle TNFR_c6 PF00020.13 KFM07499.1 - 1.4e-08 34.6 36.9 0.00018 21.5 8.2 4.8 3 1 1 4 4 4 3 TNFR/NGFR cysteine-rich region GCC2_GCC3 PF07699.8 KFM07499.1 - 0.002 17.6 1.2 0.002 17.6 0.8 4.0 3 2 0 3 3 3 1 GCC2 and GCC3 HEAT PF02985.17 KFM07500.1 - 4e-15 54.4 2.7 0.0081 16.1 0.0 7.2 6 1 1 7 7 7 3 HEAT repeat HEAT_2 PF13646.1 KFM07500.1 - 6.3e-09 36.0 0.1 0.00096 19.3 0.0 3.3 3 0 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 KFM07500.1 - 0.00034 21.0 6.4 0.87 10.1 0.0 5.2 5 1 1 6 6 6 2 HEAT-like repeat DUF4140 PF13600.1 KFM07500.1 - 0.021 15.2 1.2 5.4 7.5 0.3 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Nuc_H_symport PF03825.11 KFM07500.1 - 0.1 11.3 0.1 4.4 5.9 0.0 2.3 2 0 0 2 2 2 0 Nucleoside H+ symporter DivIC PF04977.10 KFM07500.1 - 2.1 7.8 5.6 2 7.9 0.1 2.6 2 0 0 2 2 2 0 Septum formation initiator PigN PF04987.9 KFM07502.1 - 1.4e-133 445.8 47.2 1.9e-133 445.3 32.7 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 KFM07502.1 - 4.7e-16 59.0 0.1 1.8e-15 57.1 0.1 1.8 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 KFM07502.1 - 3.1e-06 26.7 0.0 5.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 KFM07502.1 - 2.8e-05 23.4 0.0 6.3e-05 22.3 0.0 1.6 2 0 0 2 2 2 1 Sulfatase TPR_7 PF13176.1 KFM07502.1 - 0.056 13.2 0.7 0.72 9.8 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat PglZ PF08665.7 KFM07502.1 - 0.14 11.8 0.1 1.4 8.5 0.1 2.1 2 0 0 2 2 2 0 PglZ domain zf-RING_5 PF14634.1 KFM07503.1 - 1e-07 31.5 11.3 1e-07 31.5 7.8 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KFM07503.1 - 3.9e-07 29.6 12.7 7.4e-07 28.7 8.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM07503.1 - 7.2e-06 25.5 10.3 1.8e-05 24.2 7.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM07503.1 - 8.1e-06 25.5 13.1 8.1e-06 25.5 9.0 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFM07503.1 - 0.00022 21.1 13.2 0.00022 21.1 9.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFM07503.1 - 0.0006 19.6 11.8 0.0006 19.6 8.2 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KFM07503.1 - 0.0014 18.2 9.3 0.0027 17.3 6.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 KFM07503.1 - 1.9 8.1 13.7 7.2 6.2 9.5 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Cadherin PF00028.12 KFM07505.1 - 3e-81 267.7 3.2 2.1e-18 66.3 0.0 5.3 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.12 KFM07505.1 - 6.9e-52 175.4 1.4 8.3e-52 175.1 0.1 1.7 2 0 0 2 2 2 1 Cadherin cytoplasmic region Cadherin_2 PF08266.7 KFM07505.1 - 6e-05 22.5 0.0 1.3 8.6 0.0 4.3 4 0 0 4 4 4 2 Cadherin-like O-antigen_lig PF13425.1 KFM07505.1 - 0.053 13.4 0.8 0.12 12.3 0.6 1.5 1 0 0 1 1 1 0 O-antigen ligase like membrane protein 7tm_1 PF00001.16 KFM07506.1 - 5.2e-39 133.9 34.5 2.1e-37 128.6 23.9 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM07506.1 - 1.1e-10 41.1 33.8 2.1e-10 40.1 23.4 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx UPF0489 PF12640.2 KFM07507.1 - 4.7e-52 176.4 0.1 9.8e-52 175.4 0.1 1.6 1 0 0 1 1 1 1 UPF0489 domain Ribonucleas_3_3 PF14622.1 KFM07508.1 - 9.6e-43 145.2 8.6 4.5e-24 84.8 0.0 3.5 4 0 0 4 4 4 2 Ribonuclease-III-like Ribonuclease_3 PF00636.21 KFM07508.1 - 1.1e-42 145.0 0.3 4.6e-21 75.4 0.0 3.2 2 0 0 2 2 2 2 Ribonuclease III domain dsrm PF00035.20 KFM07508.1 - 9.1e-14 51.7 0.0 9.1e-14 51.7 0.0 2.2 2 0 0 2 2 2 1 Double-stranded RNA binding motif 5_3_exonuc PF01367.15 KFM07508.1 - 0.14 12.3 0.1 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Cadherin PF00028.12 KFM07509.1 - 7.8e-77 253.6 10.1 1.8e-19 69.7 0.1 5.4 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.12 KFM07509.1 - 3.4e-58 195.9 0.9 8.2e-58 194.6 0.7 1.6 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.7 KFM07509.1 - 0.00026 20.4 0.0 2.8 7.5 0.0 3.8 3 0 0 3 3 3 2 Cadherin-like ASFV_J13L PF05568.6 KFM07509.1 - 0.0045 16.5 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 African swine fever virus J13L protein 7TM_GPCR_Srw PF10324.4 KFM07509.1 - 0.11 11.6 0.2 0.16 11.0 0.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Cadherin PF00028.12 KFM07512.1 - 3e-79 261.3 2.7 2.4e-19 69.3 0.1 5.3 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.12 KFM07512.1 - 2.9e-54 183.1 0.6 7e-54 181.9 0.4 1.6 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.7 KFM07512.1 - 0.00012 21.5 0.0 1.5 8.4 0.0 3.8 4 0 0 4 4 4 2 Cadherin-like ASFV_J13L PF05568.6 KFM07512.1 - 0.07 12.6 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein Cadherin PF00028.12 KFM07515.1 - 2.2e-78 258.6 4.1 1.3e-18 66.9 0.1 5.3 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.12 KFM07515.1 - 5.2e-56 188.8 0.6 1.3e-55 187.5 0.4 1.6 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.7 KFM07515.1 - 0.00094 18.6 0.0 1.5 8.3 0.0 4.2 4 1 0 4 4 4 1 Cadherin-like ASFV_J13L PF05568.6 KFM07515.1 - 0.048 13.1 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein EHN PF06441.7 KFM07519.1 - 2.5e-34 117.5 0.3 4e-34 116.9 0.2 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KFM07519.1 - 2e-13 50.7 0.0 1e-12 48.4 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFM07519.1 - 3.2e-09 36.7 0.0 2.8e-07 30.3 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF221 PF02714.10 KFM07520.1 - 3.6e-89 298.8 21.7 3.6e-89 298.8 15.0 3.3 2 1 1 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KFM07520.1 - 8.4e-23 80.6 1.5 8.4e-23 80.6 1.0 4.8 5 0 0 5 5 5 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KFM07520.1 - 2.6e-15 56.7 1.9 5.4e-15 55.6 1.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_1 PF00076.17 KFM07520.1 - 0.00047 19.7 0.0 0.23 11.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TGFb_propeptide PF00688.13 KFM07521.1 - 1.5e-27 96.4 0.7 2.6e-27 95.6 0.5 1.3 1 1 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.15 KFM07521.1 - 1e-08 35.3 0.2 2e-08 34.4 0.1 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain Bile_Hydr_Trans PF04775.9 KFM07522.1 - 9.3e-30 102.9 0.0 1e-29 102.7 0.0 1.0 1 0 0 1 1 1 1 Acyl-CoA thioester hydrolase/BAAT N-terminal region Cupin_4 PF08007.7 KFM07523.1 - 4.3e-58 197.0 0.0 5.8e-58 196.6 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.1 KFM07523.1 - 1.4e-06 27.9 0.0 1.9e-05 24.3 0.0 2.1 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.6 KFM07523.1 - 0.0049 16.3 0.0 0.59 9.6 0.0 2.3 2 0 0 2 2 2 2 Cupin domain DUF3418 PF11898.3 KFM07523.1 - 0.026 12.9 0.0 0.035 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) NumbF PF06311.7 KFM07524.1 - 3.2e-39 132.9 6.2 4.1e-39 132.5 0.6 3.2 3 0 0 3 3 3 1 NUMB domain PID PF00640.18 KFM07524.1 - 8.6e-36 122.9 0.1 1.4e-35 122.2 0.1 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.8 KFM07524.1 - 1.9e-05 24.5 0.0 3.7e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PID_2 PF14719.1 KFM07524.1 - 5.3e-05 22.9 0.1 9.4e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) I-set PF07679.11 KFM07525.1 - 1.9e-44 149.4 0.0 2.6e-15 56.0 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin I-set domain ADAM_spacer1 PF05986.9 KFM07525.1 - 2.2e-35 120.9 0.0 3.7e-35 120.2 0.0 1.4 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Ig_2 PF13895.1 KFM07525.1 - 9.1e-35 118.6 0.1 1.5e-11 44.2 0.1 3.8 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 KFM07525.1 - 7.5e-31 106.4 8.2 3.5e-10 40.2 0.3 4.7 4 0 0 4 4 4 3 Immunoglobulin domain TSP_1 PF00090.14 KFM07525.1 - 9e-29 99.3 72.9 3.4e-08 33.4 8.3 6.6 5 0 0 5 5 5 5 Thrombospondin type 1 domain V-set PF07686.12 KFM07525.1 - 1.6e-26 92.4 0.7 7.8e-09 35.4 0.2 5.0 3 2 0 3 3 3 3 Immunoglobulin V-set domain ig PF00047.20 KFM07525.1 - 4.7e-26 90.6 0.1 2.9e-07 30.4 0.0 4.0 3 0 0 3 3 3 3 Immunoglobulin domain Kunitz_BPTI PF00014.18 KFM07525.1 - 1.1e-17 63.9 4.6 1.1e-17 63.9 3.2 4.8 5 1 0 5 5 4 1 Kunitz/Bovine pancreatic trypsin inhibitor domain PLAC PF08686.6 KFM07525.1 - 5.3e-12 45.7 7.3 2.4e-11 43.7 5.0 2.3 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain C2-set PF05790.10 KFM07525.1 - 0.0015 18.4 0.0 11 6.0 0.0 3.9 4 0 0 4 4 4 1 Immunoglobulin C2-set domain V-set_CD47 PF08204.6 KFM07525.1 - 0.011 15.5 0.0 0.097 12.4 0.0 2.5 3 0 0 3 3 3 0 CD47 immunoglobulin-like domain Presenilin PF01080.12 KFM07526.1 - 4.3e-172 572.4 21.9 6.9e-170 565.1 15.2 2.0 1 1 0 1 1 1 1 Presenilin CHD5 PF04420.9 KFM07526.1 - 4.4 6.9 7.2 0.68 9.5 1.9 1.9 2 0 0 2 2 2 0 CHD5-like protein PWI PF01480.12 KFM07527.1 - 5.8e-18 64.7 0.4 1.8e-17 63.2 0.3 1.9 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.17 KFM07527.1 - 4.9e-09 35.6 0.0 9.3e-09 34.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM07527.1 - 0.0069 16.3 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FYVE PF01363.16 KFM07528.1 - 1e-30 105.4 25.8 4.6e-17 61.6 8.1 5.6 5 1 1 6 6 6 2 FYVE zinc finger GBP PF02263.14 KFM07528.1 - 0.00045 19.3 0.0 0.0008 18.5 0.0 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain AIG1 PF04548.11 KFM07528.1 - 0.0028 16.7 0.0 0.0053 15.8 0.0 1.5 1 0 0 1 1 1 1 AIG1 family WD40 PF00400.27 KFM07529.1 - 0.014 15.2 1.9 0.43 10.5 0.0 3.5 3 1 0 3 3 3 0 WD domain, G-beta repeat Requiem_N PF14051.1 KFM07530.1 - 1.4e-37 127.4 0.2 2.5e-37 126.6 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of DPF2/REQ. PHD PF00628.24 KFM07530.1 - 2.9e-21 74.9 23.8 3.9e-12 45.6 3.6 3.3 2 1 1 3 3 3 2 PHD-finger PHD_2 PF13831.1 KFM07530.1 - 0.006 15.8 1.5 0.006 15.8 1.0 3.9 3 1 1 4 4 4 2 PHD-finger zf-PHD-like PF15446.1 KFM07530.1 - 0.0096 15.2 2.6 0.0096 15.2 1.8 3.0 3 0 0 3 3 3 2 PHD/FYVE-zinc-finger like domain zf-C2H2_4 PF13894.1 KFM07530.1 - 0.01 16.0 0.8 0.01 16.0 0.5 4.3 4 1 0 4 4 4 0 C2H2-type zinc finger C1_1 PF00130.17 KFM07530.1 - 0.033 13.9 19.0 0.89 9.3 0.3 4.3 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2 PF00096.21 KFM07530.1 - 0.036 14.4 1.2 0.036 14.4 0.9 4.9 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM07530.1 - 0.057 13.7 0.4 0.057 13.7 0.3 5.3 7 1 0 7 7 7 0 Zinc-finger double domain Prok-RING_1 PF14446.1 KFM07530.1 - 0.23 11.2 21.7 0.34 10.6 4.4 4.2 3 1 1 4 4 4 0 Prokaryotic RING finger family 1 RGS PF00615.14 KFM07531.1 - 1.4e-33 115.4 0.4 1.4e-33 115.4 0.3 2.3 2 1 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.16 KFM07531.1 - 1.3e-15 56.8 0.0 3.2e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) G-gamma PF00631.17 KFM07531.1 - 9e-15 54.1 0.1 2.1e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 GGL domain DUF1203 PF06718.6 KFM07531.1 - 0.018 14.8 0.0 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1203) DUF3401 PF11881.3 KFM07532.1 - 3.9e-93 311.2 12.9 3.9e-93 311.2 9.0 2.8 3 1 0 3 3 3 1 Domain of unknown function (DUF3401) Rap_GAP PF02145.10 KFM07532.1 - 4e-64 215.4 0.0 7.9e-64 214.5 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP PDZ PF00595.19 KFM07532.1 - 4.6e-05 23.4 0.0 9.8e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) DUF4164 PF13747.1 KFM07532.1 - 0.019 15.0 1.7 0.05 13.7 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) IncA PF04156.9 KFM07532.1 - 0.031 13.8 8.0 0.047 13.2 4.5 2.0 2 0 0 2 2 2 0 IncA protein DUF972 PF06156.8 KFM07532.1 - 0.38 11.1 3.3 1.3 9.3 2.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF904 PF06005.7 KFM07532.1 - 0.49 10.7 12.1 0.13 12.5 5.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF904) V_ATPase_I PF01496.14 KFM07532.1 - 1.9 6.2 2.2 3.1 5.5 1.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pecanex_C PF05041.10 KFM07533.1 - 4.2e-120 399.0 0.0 6.6e-120 398.3 0.0 1.3 1 0 0 1 1 1 1 Pecanex protein (C-terminus) Pkinase PF00069.20 KFM07534.1 - 5.9e-65 218.9 0.0 1.3e-64 217.9 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM07534.1 - 3.7e-64 216.2 0.0 5.3e-64 215.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3552 PF12072.3 KFM07534.1 - 0.023 13.9 10.6 0.045 12.9 7.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) OmpH PF03938.9 KFM07534.1 - 0.048 13.5 2.9 0.089 12.7 2.0 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Med6 PF04934.9 KFM07535.1 - 1.1e-44 151.4 0.1 1.5e-44 150.9 0.1 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component Peptidase_M15 PF01427.12 KFM07535.1 - 0.024 14.2 0.1 4.9 6.7 0.0 2.3 2 0 0 2 2 2 0 D-ala-D-ala dipeptidase PDZ PF00595.19 KFM07536.1 - 2.1e-20 72.6 0.0 3.1e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM07536.1 - 5.1e-08 32.7 0.1 5.9e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.1 KFM07536.1 - 0.011 15.5 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Tricorn protease PDZ domain Peptidase_C97 PF05903.9 KFM07538.1 - 4.8e-41 140.0 0.0 5.8e-41 139.7 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF3670 PF12419.3 KFM07538.1 - 0.11 11.9 0.1 0.24 10.8 0.0 1.5 2 0 0 2 2 2 0 SNF2 Helicase protein LRAT PF04970.8 KFM07538.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Calx-beta PF03160.9 KFM07540.1 - 1.4e-62 207.9 8.2 9.3e-31 105.7 0.1 2.8 3 0 0 3 3 3 2 Calx-beta domain Na_Ca_ex PF01699.19 KFM07540.1 - 5.6e-60 200.9 27.3 1.2e-34 118.9 5.9 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF1735 PF08522.5 KFM07540.1 - 0.13 12.6 2.1 1.8 9.0 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1735) Acyl_transf_3 PF01757.17 KFM07540.1 - 0.14 10.9 26.9 0.12 11.2 8.6 2.5 2 0 0 2 2 2 0 Acyltransferase family Thyroglobulin_1 PF00086.13 KFM07541.1 - 4.9e-28 96.2 27.2 6.5e-16 57.4 3.4 3.5 3 0 0 3 3 3 2 Thyroglobulin type-1 repeat SPARC_Ca_bdg PF10591.4 KFM07541.1 - 7.4e-14 51.7 0.0 1.6e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Kazal_2 PF07648.10 KFM07541.1 - 2.8e-07 30.3 3.9 2.8e-07 30.3 2.7 3.6 4 0 0 4 4 4 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 KFM07541.1 - 6e-06 26.1 5.7 6e-06 26.1 3.9 3.5 3 0 0 3 3 3 1 Kazal-type serine protease inhibitor domain EF-hand_7 PF13499.1 KFM07541.1 - 0.0019 18.3 0.0 0.0042 17.1 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KFM07541.1 - 0.01 15.6 0.1 1.8 8.6 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.27 KFM07541.1 - 0.018 14.3 0.0 1.3 8.4 0.0 2.5 2 0 0 2 2 2 0 EF hand DUF1977 PF09320.6 KFM07541.1 - 0.081 13.1 0.2 0.081 13.1 0.1 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1977) EF-hand_5 PF13202.1 KFM07541.1 - 0.13 11.6 0.0 5.1 6.6 0.0 2.5 2 0 0 2 2 2 0 EF hand RRM_1 PF00076.17 KFM07542.1 - 1.4e-31 107.9 0.1 1.7e-16 59.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM07542.1 - 3.2e-22 78.2 0.0 8.3e-10 38.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM07542.1 - 2.9e-12 46.2 0.0 3.1e-06 26.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFM07542.1 - 1.2e-07 31.4 0.1 0.00093 19.0 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 KFM07542.1 - 0.00031 20.4 0.0 0.00088 19.0 0.0 1.7 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DbpA PF03880.10 KFM07542.1 - 0.047 13.3 0.0 6.3 6.5 0.0 2.3 2 0 0 2 2 2 0 DbpA RNA binding domain CytochromB561_N PF09786.4 KFM07542.1 - 1.9 6.8 13.4 2.1 6.6 9.3 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal SOG2 PF10428.4 KFM07542.1 - 4.4 5.8 17.2 7.1 5.1 11.9 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Macoilin PF09726.4 KFM07542.1 - 8.6 4.4 16.6 9.8 4.3 11.5 1.1 1 0 0 1 1 1 0 Transmembrane protein Sushi PF00084.15 KFM07543.1 - 3.2e-09 36.9 6.5 5.9e-09 36.1 4.5 1.5 1 0 0 1 1 1 1 Sushi domain (SCR repeat) RSN1_TM PF13967.1 KFM07543.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport PH PF00169.24 KFM07544.1 - 0.00015 21.9 0.0 0.00015 21.9 0.0 2.3 2 1 0 2 2 2 1 PH domain Myosin_tail_1 PF01576.14 KFM07544.1 - 0.0052 14.5 54.5 0.021 12.5 14.9 2.0 2 0 0 2 2 2 2 Myosin tail ERM PF00769.14 KFM07544.1 - 0.009 15.5 27.1 0.009 15.5 18.8 2.4 2 0 0 2 2 2 1 Ezrin/radixin/moesin family Reo_sigmaC PF04582.7 KFM07544.1 - 0.031 13.4 7.0 0.34 10.0 0.5 2.1 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF3726 PF12525.3 KFM07544.1 - 0.68 9.7 5.7 1.8 8.3 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3726) EIF_2_alpha PF07541.7 KFM07544.1 - 0.75 9.5 4.7 0.25 11.0 0.4 2.4 2 1 1 3 3 3 0 Eukaryotic translation initiation factor 2 alpha subunit Baculo_PEP_C PF04513.7 KFM07544.1 - 1.4 8.7 12.4 0.5 10.1 1.8 2.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Zip PF02535.17 KFM07545.1 - 5e-40 137.4 22.8 1e-31 110.1 7.5 2.2 1 1 1 2 2 2 2 ZIP Zinc transporter ABC2_membrane_5 PF13346.1 KFM07545.1 - 0.047 12.9 3.1 4.4 6.5 0.1 3.2 2 1 1 3 3 3 0 ABC-2 family transporter protein 7TM-7TMR_HD PF07698.6 KFM07545.1 - 5.1 6.5 14.5 0.077 12.4 2.1 2.7 3 1 0 3 3 3 0 7TM receptor with intracellular HD hydrolase ER PF01133.12 KFM07546.1 - 5.4e-52 173.8 0.4 6e-52 173.6 0.3 1.0 1 0 0 1 1 1 1 Enhancer of rudimentary DUF3407 PF11887.3 KFM07546.1 - 0.12 11.5 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3407) Glycos_transf_2 PF00535.21 KFM07547.1 - 3.1e-23 82.3 0.0 4.9e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 KFM07547.1 - 6.6e-17 61.6 3.0 1.3e-16 60.7 2.1 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_2 PF10111.4 KFM07547.1 - 2.9e-11 42.9 0.0 8.5e-11 41.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.1 KFM07547.1 - 1.3e-09 38.2 0.0 1.8e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 KFM07547.1 - 1.8e-08 33.7 0.1 3.4e-08 32.8 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase DUF4227 PF14004.1 KFM07547.1 - 0.0082 15.9 0.3 0.016 15.0 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4227) DNA_pol_A_exo1 PF01612.15 KFM07548.1 - 1.7e-17 63.4 0.0 2.9e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease WD40 PF00400.27 KFM07549.1 - 3.7e-19 67.8 12.1 5e-05 23.0 0.1 6.2 7 0 0 7 7 7 4 WD domain, G-beta repeat Spectrin PF00435.16 KFM07550.1 - 1.3e-76 253.6 25.5 5.2e-27 94.1 4.9 4.3 4 0 0 4 4 4 4 Spectrin repeat CH PF00307.26 KFM07550.1 - 7.8e-29 99.8 0.1 1.9e-20 72.8 0.0 3.2 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 KFM07550.1 - 4.6e-26 90.5 0.0 1.9e-25 88.5 0.0 2.2 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 KFM07550.1 - 2.3e-10 39.9 0.0 7.2e-10 38.3 0.0 1.9 1 0 0 1 1 1 1 CAMSAP CH domain EF-hand_1 PF00036.27 KFM07550.1 - 2.7e-07 29.3 1.0 0.0053 15.9 0.2 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 KFM07550.1 - 5.9e-06 25.7 0.6 0.012 15.4 0.1 3.8 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.1 KFM07550.1 - 3.8e-05 23.2 1.8 0.00071 19.1 0.2 3.4 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_7 PF13499.1 KFM07550.1 - 0.00011 22.3 0.2 0.00085 19.4 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair XisI PF08869.6 KFM07550.1 - 0.0084 16.2 0.9 0.034 14.2 0.6 2.1 1 0 0 1 1 1 1 XisI protein RRM_1 PF00076.17 KFM07551.1 - 4.2e-28 96.7 0.0 1e-16 60.3 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM07551.1 - 7.5e-16 57.8 0.1 2.4e-09 37.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM07551.1 - 8.2e-13 48.0 0.0 2.2e-07 30.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.10 KFM07551.1 - 0.044 13.4 0.0 2 8.1 0.0 2.2 2 0 0 2 2 2 0 DbpA RNA binding domain OB_RNB PF08206.6 KFM07551.1 - 0.052 13.0 0.1 0.2 11.1 0.1 2.1 1 0 0 1 1 1 0 Ribonuclease B OB domain Nup35_RRM_2 PF14605.1 KFM07551.1 - 0.086 12.6 0.2 0.19 11.5 0.0 1.6 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif PRE_C2HC PF07530.6 KFM07551.1 - 0.1 12.5 0.0 1 9.3 0.0 2.4 2 1 0 2 2 2 0 Associated with zinc fingers Apt1 PF10351.4 KFM07551.1 - 7.8 5.2 16.9 10 4.8 11.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Evr1_Alr PF04777.8 KFM07552.1 - 0.17 11.8 1.7 1.2 9.0 0.1 2.1 1 1 1 2 2 2 0 Erv1 / Alr family Rad51 PF08423.6 KFM07554.1 - 1e-29 103.2 0.0 1.3e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KFM07554.1 - 4e-14 52.4 0.0 5.4e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KFM07554.1 - 2.7e-07 29.9 0.9 1.4e-06 27.5 0.6 2.0 1 1 0 1 1 1 1 KaiC RecA PF00154.16 KFM07554.1 - 1.5e-05 24.2 0.1 0.0088 15.1 0.0 2.1 2 0 0 2 2 2 2 recA bacterial DNA recombination protein DnaB_C PF03796.10 KFM07554.1 - 0.00079 18.3 0.0 0.017 14.0 0.0 2.4 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain PAXNEB PF05625.6 KFM07554.1 - 0.00092 18.1 0.0 0.0017 17.2 0.0 1.4 1 0 0 1 1 1 1 PAXNEB protein SAM_2 PF07647.12 KFM07554.1 - 0.016 15.0 0.1 0.029 14.2 0.1 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) AAA PF00004.24 KFM07554.1 - 0.051 13.7 0.1 0.24 11.6 0.0 2.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ETRAMP PF09716.5 KFM07554.1 - 0.1 12.5 0.5 10 6.1 0.0 2.4 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF1113 PF06541.6 KFM07555.1 - 1.5e-10 41.0 11.8 1.8e-10 40.7 8.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1113) TGF_beta PF00019.15 KFM07556.1 - 5.5e-37 126.2 0.1 1.4e-36 124.9 0.1 1.7 1 0 0 1 1 1 1 Transforming growth factor beta like domain FGF PF00167.13 KFM07557.1 - 4e-30 104.0 0.0 4.4e-30 103.9 0.0 1.0 1 0 0 1 1 1 1 Fibroblast growth factor VWA PF00092.23 KFM07558.1 - 8.9e-10 38.5 0.0 9.5e-10 38.4 0.0 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 KFM07558.1 - 5.9e-07 29.7 0.0 6.4e-07 29.6 0.0 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain Ant_C PF05586.6 KFM07559.1 - 7.6e-42 141.6 0.3 7.6e-42 141.6 0.2 1.5 2 0 0 2 2 2 1 Anthrax receptor C-terminus region Prolactin_RP PF15172.1 KFM07559.1 - 0.28 10.4 2.1 0.98 8.6 0.3 2.3 2 0 0 2 2 2 0 Prolactin-releasing peptide HlyIII PF03006.15 KFM07560.1 - 1.1e-43 149.1 25.7 1.3e-43 149.0 17.8 1.0 1 0 0 1 1 1 1 Haemolysin-III related SPC25 PF06703.6 KFM07560.1 - 3.4 7.2 5.6 1.4 8.4 0.3 2.4 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) BMP2K_C PF15282.1 KFM07561.1 - 4.3e-89 298.5 13.9 4.3e-89 298.5 9.7 2.7 2 2 0 2 2 2 2 BMP-2-inducible protein kinase C-terminus DivIC PF04977.10 KFM07561.1 - 0.22 11.0 3.5 0.61 9.6 2.4 1.7 1 0 0 1 1 1 0 Septum formation initiator Pkinase PF00069.20 KFM07562.1 - 2.1e-40 138.5 0.0 2.1e-40 138.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM07562.1 - 9.2e-25 87.1 0.0 9.2e-25 87.1 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM07562.1 - 4.4e-09 35.7 2.5 1.1e-07 31.0 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KFM07562.1 - 0.014 15.1 7.6 0.046 13.4 0.1 3.1 2 2 1 3 3 3 0 Phosphotransferase enzyme family YxiJ PF14176.1 KFM07562.1 - 0.078 13.0 6.6 0.2 11.7 4.6 1.7 1 0 0 1 1 1 0 YxiJ-like protein NTF2 PF02136.15 KFM07563.1 - 2.7e-32 111.6 0.1 4.5e-32 110.9 0.1 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 KFM07563.1 - 1.1e-14 53.7 0.1 2.3e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM07563.1 - 2.4e-10 40.2 0.1 5.7e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM07563.1 - 0.0049 16.6 0.0 0.0085 15.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Uso1_p115_head PF04869.9 KFM07564.1 - 4.5e-80 268.7 0.0 4.5e-80 268.7 0.0 2.6 3 0 0 3 3 3 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 KFM07564.1 - 8.3e-21 74.3 20.4 8.3e-21 74.3 14.2 3.8 2 1 1 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region Leu_zip PF15294.1 KFM07564.1 - 0.0062 15.6 11.1 0.0062 15.6 7.7 4.3 2 1 3 5 5 5 2 Leucine zipper ADIP PF11559.3 KFM07564.1 - 2.3 8.1 54.7 1.4 8.8 4.4 4.5 3 1 0 4 4 4 0 Afadin- and alpha -actinin-Binding EGF PF00008.22 KFM07565.1 - 0.00033 20.5 3.6 0.00056 19.8 2.5 1.4 1 0 0 1 1 1 1 EGF-like domain Chordopox_A33R PF05966.7 KFM07565.1 - 0.007 15.1 0.8 0.007 15.1 0.6 1.6 1 1 0 1 1 1 1 Chordopoxvirus A33R protein EphA2_TM PF14575.1 KFM07565.1 - 0.008 16.5 2.9 0.018 15.4 0.2 2.2 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 KFM07565.1 - 0.02 14.5 0.2 0.02 14.5 0.1 1.7 2 0 0 2 2 2 0 TMEM154 protein family Podoplanin PF05808.6 KFM07565.1 - 0.065 12.8 0.0 0.071 12.6 0.0 1.2 1 0 0 1 1 1 0 Podoplanin Protocadherin PF08374.6 KFM07565.1 - 0.078 12.6 0.3 0.078 12.6 0.2 2.1 2 0 0 2 2 2 0 Protocadherin DUF3377 PF11857.3 KFM07565.1 - 0.088 12.4 0.4 0.25 11.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) FtsL PF04999.8 KFM07565.1 - 0.11 12.1 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 Cell division protein FtsL EGF_2 PF07974.8 KFM07565.1 - 0.3 11.3 5.0 0.55 10.4 3.5 1.5 1 0 0 1 1 1 0 EGF-like domain EGF PF00008.22 KFM07566.1 - 6.2e-06 26.0 3.0 6.2e-06 26.0 2.1 1.6 2 0 0 2 2 2 1 EGF-like domain hEGF PF12661.2 KFM07566.1 - 0.0093 15.9 1.4 0.0093 15.9 1.0 2.1 2 0 0 2 2 2 1 Human growth factor-like EGF EGF_2 PF07974.8 KFM07566.1 - 0.075 13.2 3.3 0.18 11.9 2.3 1.7 1 1 0 1 1 1 0 EGF-like domain m04gp34like PF12216.3 KFM07566.1 - 0.081 12.2 0.6 0.1 11.9 0.4 1.1 1 0 0 1 1 1 0 Immune evasion protein DUF1180 PF06679.7 KFM07566.1 - 0.17 11.7 0.4 0.22 11.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) EGF PF00008.22 KFM07567.1 - 0.0029 17.5 3.6 0.006 16.5 2.5 1.6 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.2 KFM07567.1 - 0.0039 17.1 0.5 0.0094 15.9 0.4 1.7 1 0 0 1 1 1 1 Human growth factor-like EGF DUF4187 PF13821.1 KFM07567.1 - 0.11 12.0 1.3 0.2 11.2 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) Rad60-SLD_2 PF13881.1 KFM07567.1 - 0.13 12.1 0.1 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like SKG6 PF08693.5 KFM07567.1 - 0.15 11.4 0.3 0.31 10.3 0.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Laminin_EGF PF00053.19 KFM07567.1 - 0.32 10.9 3.5 0.68 9.9 2.4 1.6 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 KFM07567.1 - 2.7 8.2 5.6 12 6.1 3.9 2.1 1 1 0 1 1 1 0 EGF-like domain THF_DHG_CYH_C PF02882.14 KFM07568.1 - 4.9e-62 207.7 4.0 6.9e-62 207.2 2.7 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 KFM07568.1 - 1.1e-38 131.8 0.3 1.7e-38 131.2 0.2 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain IL8 PF00048.15 KFM07569.1 - 2.1e-20 72.4 0.5 2.7e-20 72.1 0.4 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like IL8 PF00048.15 KFM07570.1 - 7.2e-19 67.5 0.4 9.5e-19 67.1 0.3 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like RA PF00788.18 KFM07571.1 - 8.6e-12 45.3 0.0 2e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Ras_bdg_2 PF14847.1 KFM07571.1 - 0.017 15.0 0.0 0.12 12.3 0.0 2.3 2 0 0 2 2 2 0 Ras-binding domain of Byr2 YusW PF14039.1 KFM07571.1 - 0.039 14.2 0.3 0.15 12.3 0.0 2.1 2 0 0 2 2 2 0 YusW-like protein RecO_C PF02565.10 KFM07571.1 - 0.091 12.6 0.1 0.32 10.8 0.1 2.0 1 1 0 1 1 1 0 Recombination protein O C terminal Serum_albumin PF00273.15 KFM07572.1 - 1.9e-131 434.5 40.1 1.8e-53 180.5 6.3 3.0 3 0 0 3 3 3 3 Serum albumin family VitD-bind_III PF09164.5 KFM07572.1 - 3.1e-08 33.0 13.0 0.0013 18.3 0.5 5.3 5 0 0 5 5 5 4 Vitamin D binding protein, domain III Serum_albumin PF00273.15 KFM07573.1 - 3.8e-142 469.4 35.5 5.9e-55 185.4 3.7 3.0 3 0 0 3 3 3 3 Serum albumin family VitD-bind_III PF09164.5 KFM07573.1 - 2.3e-07 30.3 12.6 0.012 15.2 0.0 6.1 6 0 0 6 6 6 3 Vitamin D binding protein, domain III CYTL1 PF15153.1 KFM07573.1 - 0.0076 15.9 9.9 0.015 14.9 0.2 3.7 3 1 0 3 3 3 1 Cytokine-like protein 1 DUF2633 PF11119.3 KFM07573.1 - 0.43 10.3 1.5 0.98 9.1 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) 60KD_IMP PF02096.15 KFM07575.1 - 1.2e-24 87.1 0.0 1.4e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein ADAM_spacer1 PF05986.9 KFM07576.1 - 5.6e-32 109.9 0.0 1.1e-31 109.0 0.0 1.5 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Pep_M12B_propep PF01562.14 KFM07576.1 - 1.5e-28 99.2 0.0 3.1e-28 98.1 0.0 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide TSP_1 PF00090.14 KFM07576.1 - 2.3e-24 85.2 60.3 3.1e-10 39.9 3.8 6.1 6 0 0 6 6 6 4 Thrombospondin type 1 domain Reprolysin PF01421.14 KFM07576.1 - 7.2e-21 74.6 0.0 1.5e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.1 KFM07576.1 - 3.6e-14 53.1 0.8 7.7e-14 52.0 0.5 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KFM07576.1 - 2.3e-11 44.3 0.4 5.3e-11 43.1 0.3 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFM07576.1 - 5.6e-11 42.7 3.6 5.7e-11 42.7 0.8 2.2 3 0 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFM07576.1 - 1.1e-09 38.1 0.2 3.9e-09 36.3 0.2 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like PLAC PF08686.6 KFM07576.1 - 6.3e-05 23.1 4.8 0.00047 20.3 3.3 2.7 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain Peptidase_M10 PF00413.19 KFM07576.1 - 0.0007 19.3 0.5 0.0015 18.3 0.1 1.7 2 0 0 2 2 2 1 Matrixin Peptidase_M7 PF02031.11 KFM07576.1 - 0.048 13.3 0.1 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family RELT PF12606.3 KFM07577.1 - 4.6e-18 64.0 0.9 4.6e-18 64.0 0.6 1.9 2 1 0 2 2 2 1 Tumour necrosis factor receptor superfamily member 19 SieB PF14163.1 KFM07577.1 - 0.091 12.3 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Superinfection exclusion protein B CM_2 PF01817.16 KFM07577.1 - 0.092 12.8 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Chorismate mutase type II Cadherin PF00028.12 KFM07579.1 - 1.5e-115 377.7 5.5 6.9e-23 80.7 0.0 7.3 7 0 0 7 7 7 7 Cadherin domain Protocadherin PF08374.6 KFM07579.1 - 2e-86 289.1 1.9 6.7e-86 287.5 1.3 2.0 1 0 0 1 1 1 1 Protocadherin Cadherin_2 PF08266.7 KFM07579.1 - 1.7e-12 46.7 0.0 3e-05 23.5 0.0 5.6 6 0 0 6 6 6 2 Cadherin-like DUF1510 PF07423.6 KFM07579.1 - 0.0055 16.1 0.2 0.011 15.1 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) MLANA PF14991.1 KFM07579.1 - 0.047 13.7 0.0 0.095 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein melan-A EphA2_TM PF14575.1 KFM07579.1 - 0.081 13.3 0.1 0.23 11.8 0.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Mid2 PF04478.7 KFM07579.1 - 0.099 12.0 0.2 0.36 10.2 0.0 1.9 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Syndecan PF01034.15 KFM07579.1 - 0.12 12.0 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 Syndecan domain Herpes_gE PF02480.11 KFM07579.1 - 0.13 10.4 0.0 0.24 9.6 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Shisa PF13908.1 KFM07579.1 - 0.21 11.7 1.0 0.3 11.2 0.0 1.7 2 0 0 2 2 1 0 Wnt and FGF inhibitory regulator IncA PF04156.9 KFM07579.1 - 0.3 10.6 0.0 0.49 9.9 0.0 1.3 1 0 0 1 1 1 0 IncA protein Sel1 PF08238.7 KFM07581.1 - 5.2e-27 93.6 18.1 2.3e-09 37.5 0.2 5.2 5 0 0 5 5 5 4 Sel1 repeat TPR_6 PF13174.1 KFM07581.1 - 0.0022 18.3 3.2 1.7 9.3 0.0 4.1 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 KFM07581.1 - 0.0053 16.3 11.3 0.12 12.0 1.8 3.4 2 1 2 4 4 4 3 TPR repeat TPR_16 PF13432.1 KFM07581.1 - 0.0084 16.7 13.6 0.013 16.1 0.1 3.6 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFM07581.1 - 0.046 13.5 1.9 9.2 6.3 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 KFM07581.1 - 0.6 10.1 14.8 4.1 7.5 0.0 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFM07581.1 - 0.71 9.5 11.4 22 4.8 0.1 5.6 5 1 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.13 KFM07581.1 - 1.6 8.6 8.2 19 5.2 0.3 3.7 3 2 0 3 3 3 0 MIT (microtubule interacting and transport) domain UPF0020 PF01170.13 KFM07582.1 - 5.4e-14 52.1 0.0 1.4e-13 50.7 0.0 1.7 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 KFM07582.1 - 2.3e-07 30.8 0.0 4.4e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 KFM07582.1 - 1.4e-05 24.3 0.0 2.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 N-6 DNA Methylase N6_N4_Mtase PF01555.13 KFM07582.1 - 0.0035 16.8 0.1 0.42 10.0 0.0 2.4 2 0 0 2 2 2 2 DNA methylase Methyltransf_15 PF09445.5 KFM07582.1 - 0.063 12.8 0.1 0.28 10.7 0.0 2.1 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase RVT_1 PF00078.22 KFM07583.1 - 0.014 14.8 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) FGF PF00167.13 KFM07585.1 - 5.6e-46 155.2 0.2 6.7e-46 155.0 0.1 1.1 1 0 0 1 1 1 1 Fibroblast growth factor EF-hand_8 PF13833.1 KFM07586.1 - 1.1e-11 44.2 14.6 3.7e-08 32.8 0.0 5.5 6 1 0 6 6 6 2 EF-hand domain pair EF-hand_7 PF13499.1 KFM07586.1 - 4.5e-10 39.5 5.4 1.7e-05 24.8 0.1 4.0 2 2 3 5 5 5 3 EF-hand domain pair EF-hand_1 PF00036.27 KFM07586.1 - 3.3e-08 32.2 14.2 0.0011 18.0 0.1 5.5 6 0 0 6 6 6 2 EF hand EF-hand_6 PF13405.1 KFM07586.1 - 1.6e-06 27.4 9.3 0.0085 15.9 0.2 4.4 5 0 0 5 5 5 2 EF-hand domain EF-hand_4 PF12763.2 KFM07586.1 - 0.0062 16.2 0.7 0.039 13.6 0.0 2.6 2 2 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand MHC_I PF00129.13 KFM07586.1 - 0.039 13.3 0.4 0.085 12.1 0.3 1.5 1 0 0 1 1 1 0 Class I Histocompatibility antigen, domains alpha 1 and 2 EF-hand_5 PF13202.1 KFM07586.1 - 0.23 10.8 7.6 8 6.0 0.7 3.9 3 0 0 3 3 3 0 EF hand zf-DHHC PF01529.15 KFM07587.1 - 5.6e-44 149.6 10.8 8.3e-44 149.0 7.5 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase Spt4 PF06093.8 KFM07587.1 - 1 9.2 6.3 2.1 8.2 4.4 1.5 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger HemY_N PF07219.8 KFM07587.1 - 1.2 8.6 0.0 1.2 8.6 0.0 2.4 2 1 1 3 3 3 0 HemY protein N-terminus MRP-63 PF14978.1 KFM07588.1 - 3.7e-38 129.8 5.0 4.3e-38 129.6 3.5 1.0 1 0 0 1 1 1 1 Mitochondrial ribosome protein 63 SAP18 PF06487.7 KFM07590.1 - 2e-44 150.2 0.0 2.3e-44 150.0 0.0 1.0 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Pkinase PF00069.20 KFM07591.1 - 9.2e-58 195.4 0.1 2.7e-37 128.3 0.1 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFM07591.1 - 6.1e-29 100.8 0.1 1.7e-20 73.2 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase_C PF00433.19 KFM07591.1 - 1e-05 25.9 1.4 2.8e-05 24.5 0.9 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain UBA PF00627.26 KFM07591.1 - 5.9e-05 22.7 0.4 0.00018 21.1 0.3 1.9 2 0 0 2 2 2 1 UBA/TS-N domain Kinase-like PF14531.1 KFM07591.1 - 0.0037 16.2 0.1 0.0096 14.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KFM07591.1 - 0.0075 16.0 0.2 0.062 13.0 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KFM07591.1 - 0.037 13.0 0.0 0.077 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CRM1_C PF08767.6 KFM07593.1 - 1.3e-05 24.2 1.1 1.3e-05 24.2 0.7 2.5 2 1 0 2 2 2 1 CRM1 C terminal N6-adenineMlase PF10237.4 KFM07594.1 - 2.4e-65 219.1 0.0 3e-65 218.8 0.0 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.10 KFM07594.1 - 0.00086 18.7 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.1 KFM07594.1 - 0.0012 18.5 0.0 0.003 17.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFM07594.1 - 0.043 13.8 0.0 0.052 13.5 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain IL17 PF06083.6 KFM07595.1 - 3e-29 100.9 0.2 3.7e-29 100.6 0.1 1.1 1 0 0 1 1 1 1 Interleukin-17 TPR_1 PF00515.23 KFM07596.1 - 1.9e-39 131.6 24.6 9.4e-07 28.1 0.0 11.6 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_11 PF13414.1 KFM07596.1 - 5.8e-38 128.3 26.8 3.4e-11 42.6 0.4 7.6 5 2 3 9 9 9 7 TPR repeat TPR_2 PF07719.12 KFM07596.1 - 8.6e-38 125.2 16.0 3.7e-05 23.2 0.1 12.3 12 0 0 12 12 12 8 Tetratricopeptide repeat TPR_12 PF13424.1 KFM07596.1 - 7.8e-31 105.8 23.0 2.8e-08 33.5 0.1 8.5 4 3 5 9 9 9 8 Tetratricopeptide repeat TPR_7 PF13176.1 KFM07596.1 - 1.5e-26 90.0 7.2 0.00029 20.4 0.0 11.2 10 1 1 11 11 11 4 Tetratricopeptide repeat TPR_19 PF14559.1 KFM07596.1 - 3.6e-24 84.8 3.9 0.0002 21.6 0.1 7.2 5 3 3 8 8 8 5 Tetratricopeptide repeat TPR_6 PF13174.1 KFM07596.1 - 1.7e-23 81.3 17.2 0.037 14.4 0.0 10.8 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_8 PF13181.1 KFM07596.1 - 3.8e-22 76.3 30.1 0.00074 19.1 0.1 11.7 10 1 1 11 11 11 7 Tetratricopeptide repeat TPR_16 PF13432.1 KFM07596.1 - 4.5e-22 78.1 0.0 0.00025 21.5 0.0 7.1 5 3 1 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 KFM07596.1 - 1.2e-20 72.1 0.1 0.02 15.4 0.0 10.3 5 3 6 11 11 11 4 Tetratricopeptide repeat Apc3 PF12895.2 KFM07596.1 - 9.9e-15 54.4 23.5 9.1e-06 25.7 1.2 6.8 2 2 6 8 8 8 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 KFM07596.1 - 2.2e-07 30.5 10.1 0.065 13.1 0.1 8.2 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFM07596.1 - 6.1e-07 29.1 31.9 0.027 14.6 0.2 10.8 12 1 0 12 12 11 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFM07596.1 - 2.3e-05 24.1 0.2 0.76 9.6 0.0 5.5 5 2 2 7 7 6 1 Tetratricopeptide repeat TPR_20 PF14561.1 KFM07596.1 - 0.00032 20.7 5.1 1.7 8.8 0.1 5.8 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.1 KFM07596.1 - 0.00068 18.7 10.6 0.085 11.9 0.1 4.5 2 1 4 6 6 6 2 Tetratricopeptide repeat Sel1 PF08238.7 KFM07596.1 - 0.0066 17.0 13.7 3 8.6 0.0 6.4 6 0 0 6 6 5 1 Sel1 repeat NARP1 PF12569.3 KFM07596.1 - 0.025 13.3 17.5 0.025 13.3 3.6 4.5 2 2 0 2 2 2 0 NMDA receptor-regulated protein 1 3HCDH_N PF02737.13 KFM07598.1 - 1.6e-48 164.7 0.0 2.1e-48 164.3 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KFM07598.1 - 3e-15 56.3 0.0 5.5e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Connexin PF00029.14 KFM07599.1 - 2.3e-50 169.1 0.4 2.3e-50 169.1 0.3 2.0 2 1 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 KFM07599.1 - 1.2e-32 111.5 5.5 2.7e-32 110.3 3.8 1.6 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain 7tm_1 PF00001.16 KFM07599.1 - 0.0032 16.6 4.6 0.12 11.5 0.3 2.2 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) EphA2_TM PF14575.1 KFM07599.1 - 0.05 14.0 0.3 15 6.0 0.0 3.0 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain COX6A PF02046.10 KFM07599.1 - 0.081 12.8 0.4 0.081 12.8 0.3 2.5 2 1 0 3 3 3 0 Cytochrome c oxidase subunit VIa Connexin PF00029.14 KFM07600.1 - 8.5e-51 170.5 0.3 8.5e-51 170.5 0.2 1.8 2 1 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 KFM07600.1 - 1.4e-31 108.1 4.7 3.1e-31 106.9 3.2 1.6 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain MFS_1 PF07690.11 KFM07600.1 - 0.038 12.7 0.4 0.064 11.9 0.2 1.3 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF1286 PF06939.6 KFM07600.1 - 0.058 13.5 0.1 0.19 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1286) COX6A PF02046.10 KFM07600.1 - 0.15 12.0 1.0 1.2 9.0 0.1 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase subunit VIa Connexin PF00029.14 KFM07601.1 - 2.1e-53 178.8 1.3 2.7e-53 178.5 0.1 1.7 2 0 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 KFM07601.1 - 1.7e-33 114.2 2.6 3.1e-33 113.4 1.8 1.4 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain RRM_1 PF00076.17 KFM07602.1 - 7.9e-34 115.1 0.0 3.4e-16 58.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NOPS PF08075.6 KFM07602.1 - 2e-31 108.1 3.9 4e-31 107.1 2.1 1.9 2 0 0 2 2 2 1 NOPS (NUC059) domain RRM_6 PF14259.1 KFM07602.1 - 1.1e-22 79.7 0.0 1.1e-11 44.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM07602.1 - 5.2e-13 48.6 0.0 1.1e-06 28.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFM07602.1 - 0.03 14.1 0.3 11 5.8 0.0 2.7 3 0 0 3 3 3 0 RNA binding motif HMG_box_2 PF09011.5 KFM07602.1 - 0.63 10.4 5.7 1.1 9.6 3.9 1.4 1 0 0 1 1 1 0 HMG-box domain Ank_2 PF12796.2 KFM07603.1 - 1.1e-26 92.9 5.6 1.7e-14 53.8 0.8 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFM07603.1 - 5e-20 70.2 1.7 2.6e-07 30.0 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 KFM07603.1 - 1.2e-19 69.8 0.1 2.1e-09 37.3 0.0 4.0 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFM07603.1 - 1.8e-17 63.2 0.5 6.7e-06 26.4 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM07603.1 - 1.9e-14 52.3 0.7 3.2e-05 23.7 0.0 4.3 5 0 0 5 5 5 3 Ankyrin repeat Chromo PF00385.19 KFM07603.1 - 9.9e-10 37.9 0.7 3.9e-09 36.0 0.5 2.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tcp10_C PF07202.8 KFM07605.1 - 3.2e-90 300.4 8.5 4.8e-90 299.8 5.9 1.3 1 0 0 1 1 1 1 T-complex protein 10 C-terminus MORN_2 PF07661.8 KFM07605.1 - 7.1e-05 22.4 4.2 32 5.0 0.0 6.9 6 3 2 8 8 8 0 MORN repeat variant DUF4520 PF15016.1 KFM07605.1 - 0.00012 21.6 0.1 0.61 9.6 0.0 3.8 1 1 2 3 3 3 2 Domain of unknown function (DUF4520) Plant_vir_prot PF01307.12 KFM07605.1 - 0.063 13.0 2.5 4 7.2 0.0 2.9 1 1 2 3 3 3 0 Plant viral movement protein GPI-anchored PF10342.4 KFM07605.1 - 0.073 13.5 0.1 0.17 12.3 0.1 1.6 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family TUDOR PF00567.19 KFM07606.1 - 2.1e-90 298.7 9.1 2.5e-21 75.7 0.1 7.4 6 2 0 6 6 6 5 Tudor domain Agenet PF05641.7 KFM07606.1 - 9.7e-05 22.4 0.3 6.3 7.0 0.0 4.6 4 0 0 4 4 4 2 Agenet domain FtsK_SpoIIIE PF01580.13 KFM07606.1 - 0.043 13.2 0.0 0.25 10.8 0.0 2.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family RA PF00788.18 KFM07607.1 - 9.3e-13 48.4 0.0 5.5e-12 46.0 0.0 2.3 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain PH PF00169.24 KFM07607.1 - 0.0037 17.4 4.3 0.32 11.2 0.9 2.6 2 1 0 2 2 2 2 PH domain Ras_bdg_2 PF14847.1 KFM07607.1 - 0.011 15.5 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 0 Ras-binding domain of Byr2 Dynein_heavy PF03028.10 KFM07609.1 - 1.2e-248 826.7 0.0 1.4e-248 826.6 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor PLDc_2 PF13091.1 KFM07610.1 - 1.6e-15 56.9 0.0 3.4e-07 30.0 0.0 3.0 3 0 0 3 3 3 2 PLD-like domain PLDc PF00614.17 KFM07610.1 - 0.59 10.0 3.2 4.7 7.1 0.1 2.9 3 0 0 3 3 3 0 Phospholipase D Active site motif SH2 PF00017.19 KFM07611.1 - 1.9e-10 40.3 0.0 3.7e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 SH2 domain SOCS_box PF07525.11 KFM07611.1 - 2.4e-08 33.6 0.0 4.4e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 SOCS box Beta_elim_lyase PF01212.16 KFM07612.1 - 8.5e-27 94.0 0.1 1.1e-26 93.6 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase TK PF00265.13 KFM07613.1 - 9.8e-59 197.8 0.2 1.2e-58 197.6 0.1 1.1 1 0 0 1 1 1 1 Thymidine kinase zf-UBR PF02207.15 KFM07613.1 - 0.11 12.2 0.6 5.8 6.7 0.1 2.3 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) HNH_5 PF14279.1 KFM07613.1 - 0.14 12.2 0.3 3.5 7.7 0.0 2.3 2 0 0 2 2 2 0 HNH endonuclease MARVEL PF01284.18 KFM07614.1 - 5.5e-18 65.1 16.2 6.9e-18 64.8 11.2 1.1 1 0 0 1 1 1 1 Membrane-associating domain Arf PF00025.16 KFM07615.1 - 9.3e-15 54.2 0.0 1e-14 54.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFM07615.1 - 0.002 17.5 0.0 0.0022 17.4 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 KFM07615.1 - 0.042 13.3 0.3 0.053 13.0 0.2 1.3 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein Mito_carr PF00153.22 KFM07616.1 - 4e-44 148.2 3.1 1.5e-19 69.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein AMOP PF03782.12 KFM07616.1 - 0.13 12.2 2.1 3.6 7.5 0.0 2.2 1 1 1 2 2 2 0 AMOP domain HRM PF02793.17 KFM07617.1 - 2e-16 59.7 4.1 3.5e-16 58.9 2.9 1.4 1 0 0 1 1 1 1 Hormone receptor domain FAM195 PF14799.1 KFM07618.1 - 4.1e-09 36.1 0.0 4.3e-09 36.1 0.0 1.0 1 0 0 1 1 1 1 FAM195 family Ank PF00023.25 KFM07619.1 - 9.1e-16 56.7 0.2 7.3e-09 35.0 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KFM07619.1 - 9.5e-16 57.9 0.0 1.1e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFM07619.1 - 1.6e-13 50.7 0.0 2.1e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM07619.1 - 6.7e-13 48.4 0.5 2.2e-10 40.4 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM07619.1 - 2.7e-10 39.4 0.2 0.00097 19.1 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Thioredoxin PF00085.15 KFM07620.1 - 1.8e-58 194.6 0.6 1.1e-28 98.8 0.0 3.8 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 KFM07620.1 - 1.3e-50 171.7 7.5 1.9e-44 151.6 2.8 3.1 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 KFM07620.1 - 4.8e-13 49.2 0.8 5e-05 23.4 0.1 3.9 2 2 0 2 2 2 2 Thioredoxin-like domain ERp29_N PF07912.8 KFM07620.1 - 1.2e-10 41.3 1.0 0.23 11.3 0.1 4.3 4 0 0 4 4 4 4 ERp29, N-terminal domain Thioredoxin_7 PF13899.1 KFM07620.1 - 4.3e-10 39.4 0.0 0.0012 18.8 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.1 KFM07620.1 - 5.4e-10 39.2 0.2 0.00044 20.3 0.0 4.1 3 1 1 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.16 KFM07620.1 - 1.6e-05 24.6 0.7 0.23 11.1 0.0 3.3 3 1 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.5 KFM07620.1 - 0.00034 20.1 0.4 0.07 12.6 0.0 2.7 2 1 0 2 2 2 1 Redoxin Thioredoxin_9 PF14595.1 KFM07620.1 - 0.0092 15.5 0.1 2.3 7.7 0.1 2.8 2 1 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.1 KFM07620.1 - 0.012 15.3 0.0 3.9 7.3 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin domain Glutaredoxin PF00462.19 KFM07620.1 - 0.016 15.1 1.3 1.1 9.2 0.0 3.4 3 1 0 3 3 2 0 Glutaredoxin HyaE PF07449.6 KFM07620.1 - 0.041 13.7 0.0 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_4 PF13462.1 KFM07620.1 - 0.14 12.1 1.2 5.8 6.8 0.1 3.3 2 2 0 2 2 2 0 Thioredoxin Rho_GDI PF02115.12 KFM07621.1 - 3.3e-96 320.4 0.6 3.6e-96 320.3 0.4 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor RRM_1 PF00076.17 KFM07622.1 - 3.7e-09 36.0 0.0 6e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 KFM07622.1 - 2.4e-08 34.2 6.3 4.6e-08 33.3 4.3 1.5 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 KFM07622.1 - 2.5e-08 33.6 0.0 7.6e-08 32.0 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM07622.1 - 3.2e-07 30.2 0.0 7.4e-07 29.0 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CTP_transf_2 PF01467.21 KFM07623.1 - 6.3e-27 94.5 0.0 2.8e-14 53.4 0.0 2.2 2 0 0 2 2 2 2 Cytidylyltransferase FAD_syn PF06574.7 KFM07623.1 - 0.008 15.8 0.0 0.057 13.0 0.0 2.1 2 0 0 2 2 2 1 FAD synthetase CHAP PF05257.11 KFM07623.1 - 0.075 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 CHAP domain SIR2 PF02146.12 KFM07624.1 - 6.6e-25 87.8 3.4 2.7e-22 79.3 0.7 2.1 1 1 1 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.17 KFM07624.1 - 0.00087 19.0 0.0 0.45 10.2 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain bZIP_Maf PF03131.12 KFM07626.1 - 9.1e-34 115.6 11.7 1.2e-33 115.3 8.1 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor DivIC PF04977.10 KFM07626.1 - 8.4e-05 21.9 5.8 8.4e-05 21.9 4.0 2.2 1 1 1 2 2 2 1 Septum formation initiator bZIP_1 PF00170.16 KFM07626.1 - 0.0009 19.1 16.1 0.013 15.4 11.2 2.3 1 1 0 1 1 1 1 bZIP transcription factor ERM PF00769.14 KFM07626.1 - 0.001 18.6 3.6 0.0012 18.4 2.5 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF2046 PF09755.4 KFM07626.1 - 0.0041 16.0 1.1 0.0041 16.0 0.8 1.9 1 1 1 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) DUF1192 PF06698.6 KFM07626.1 - 0.0047 16.7 7.6 0.052 13.3 0.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) DUF972 PF06156.8 KFM07626.1 - 0.012 15.8 3.7 0.012 15.8 2.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF342 PF03961.8 KFM07626.1 - 0.013 13.9 5.0 0.016 13.6 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 KFM07626.1 - 0.013 14.6 7.4 0.015 14.3 5.1 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Tox-ODYAM1 PF15642.1 KFM07626.1 - 0.028 13.0 3.4 0.035 12.7 2.4 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Spc24 PF08286.6 KFM07626.1 - 0.035 13.8 1.2 0.035 13.8 0.8 1.6 2 0 0 2 2 1 0 Spc24 subunit of Ndc80 HTH_Crp_2 PF13545.1 KFM07626.1 - 0.06 13.1 0.4 0.13 12.1 0.3 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HALZ PF02183.13 KFM07626.1 - 0.066 12.9 9.1 0.074 12.7 2.4 2.7 1 1 1 2 2 2 0 Homeobox associated leucine zipper DUF4164 PF13747.1 KFM07626.1 - 0.11 12.6 8.4 0.25 11.4 5.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) AAA_13 PF13166.1 KFM07626.1 - 0.15 10.4 2.9 0.18 10.1 2.0 1.0 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.4 KFM07626.1 - 0.18 10.6 8.4 0.22 10.4 5.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FimP PF09766.4 KFM07626.1 - 0.18 10.8 5.3 0.23 10.4 3.7 1.1 1 0 0 1 1 1 0 Fms-interacting protein HGTP_anticodon2 PF12745.2 KFM07626.1 - 0.2 10.7 3.6 0.28 10.2 2.5 1.3 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs bZIP_2 PF07716.10 KFM07626.1 - 0.21 11.4 16.9 0.06 13.1 8.0 2.6 1 1 2 3 3 3 0 Basic region leucine zipper IncA PF04156.9 KFM07626.1 - 0.23 11.0 12.1 0.041 13.4 3.8 2.0 1 1 1 2 2 2 0 IncA protein TMF_DNA_bd PF12329.3 KFM07626.1 - 0.25 11.1 11.9 0.05 13.4 3.8 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Kinesin-relat_1 PF12711.2 KFM07626.1 - 0.28 11.5 7.5 0.068 13.5 2.1 2.0 2 0 0 2 2 2 0 Kinesin motor DUF3584 PF12128.3 KFM07626.1 - 0.34 8.1 8.1 0.38 8.0 5.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Rop-like PF05082.8 KFM07626.1 - 0.38 10.2 3.7 0.19 11.2 0.6 2.0 2 0 0 2 2 2 0 Rop-like Mnd1 PF03962.10 KFM07626.1 - 0.5 10.0 7.6 0.71 9.5 5.3 1.3 1 0 0 1 1 1 0 Mnd1 family DUF1043 PF06295.7 KFM07626.1 - 0.51 9.9 3.4 0.51 9.9 1.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) Nnf1 PF03980.9 KFM07626.1 - 0.63 10.0 7.1 2.1 8.3 4.9 1.8 1 1 0 1 1 1 0 Nnf1 V_ATPase_I PF01496.14 KFM07626.1 - 0.7 7.6 2.5 0.81 7.4 1.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2968 PF11180.3 KFM07626.1 - 0.84 8.9 8.8 1.9 7.8 6.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) DASH_Spc19 PF08287.6 KFM07626.1 - 1.1 8.8 10.1 1.6 8.3 7.0 1.2 1 0 0 1 1 1 0 Spc19 NUDE_C PF04880.8 KFM07626.1 - 1.4 9.2 8.3 2.6 8.3 0.7 2.1 1 1 1 2 2 2 0 NUDE protein, C-terminal conserved region NYD-SP28_assoc PF14775.1 KFM07626.1 - 2.1 8.0 6.0 0.69 9.6 1.4 2.3 2 1 1 3 3 3 0 Sperm tail C-terminal domain Mst1_SARAH PF11629.3 KFM07626.1 - 2.5 8.0 9.5 15 5.4 1.9 3.0 2 1 0 2 2 2 0 C terminal SARAH domain of Mst1 Seryl_tRNA_N PF02403.17 KFM07626.1 - 2.6 8.0 9.8 4.3 7.4 6.6 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain AAA_23 PF13476.1 KFM07626.1 - 3 8.1 5.9 3.8 7.7 4.1 1.2 1 0 0 1 1 1 0 AAA domain DUF4140 PF13600.1 KFM07626.1 - 3.2 8.2 9.7 2 8.9 2.9 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF724 PF05266.9 KFM07626.1 - 3.3 7.2 9.3 6.7 6.2 6.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF465 PF04325.8 KFM07626.1 - 3.4 7.4 8.1 7.7 6.3 0.1 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF465) DUF3086 PF11285.3 KFM07626.1 - 5.1 5.8 7.1 2.3 6.9 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3086) DUF904 PF06005.7 KFM07626.1 - 5.2 7.4 13.3 44 4.4 9.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF904) OmpH PF03938.9 KFM07626.1 - 5.9 6.8 11.7 10 6.0 8.1 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Bap31 PF05529.7 KFM07626.1 - 6.8 6.0 9.5 10 5.5 6.6 1.4 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like P5CR_dimer PF14748.1 KFM07627.1 - 7.7e-40 135.2 0.0 1.2e-39 134.6 0.0 1.3 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation MARVEL PF01284.18 KFM07628.1 - 3.6e-24 85.2 43.4 1.3e-13 50.9 8.9 2.0 2 0 0 2 2 2 2 Membrane-associating domain PK_C PF02887.11 KFM07628.1 - 0.083 12.4 0.6 10 5.7 0.0 2.6 3 0 0 3 3 3 0 Pyruvate kinase, alpha/beta domain PAE PF03283.8 KFM07629.1 - 2.8e-77 259.7 0.0 3.5e-77 259.5 0.0 1.1 1 0 0 1 1 1 1 Pectinacetylesterase UPF0180 PF03698.8 KFM07629.1 - 0.15 11.9 0.1 21 5.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) UBX PF00789.15 KFM07630.1 - 6.1e-12 45.4 0.0 3e-06 27.1 0.0 2.7 2 0 0 2 2 2 2 UBX domain TUG-UBL1 PF11470.3 KFM07630.1 - 4.6e-07 29.6 0.1 8.4e-07 28.8 0.1 1.5 1 0 0 1 1 1 1 GLUT4 regulating protein TUG LRR_6 PF13516.1 KFM07631.1 - 5.2e-10 38.3 11.8 0.026 14.5 0.1 5.8 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.28 KFM07631.1 - 9.3e-08 31.0 2.7 2.4 8.4 0.0 5.6 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_4 PF12799.2 KFM07631.1 - 2.7e-07 30.0 11.8 0.0096 15.5 1.9 3.8 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM07631.1 - 0.00013 21.6 13.0 0.035 13.8 0.4 3.7 2 1 1 3 3 3 3 Leucine rich repeat LRR_7 PF13504.1 KFM07631.1 - 0.0033 17.3 7.3 22 5.8 0.0 6.0 5 0 0 5 5 5 1 Leucine rich repeat Baculo_PEP_C PF04513.7 KFM07631.1 - 0.28 11.0 26.8 0.019 14.7 1.4 3.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ras PF00071.17 KFM07632.1 - 3.8e-50 169.4 0.0 4.3e-50 169.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM07632.1 - 4.9e-13 49.6 0.0 6.5e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM07632.1 - 3.5e-05 23.1 0.0 4.3e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family adh_short_C2 PF13561.1 KFM07633.1 - 2.9e-21 76.3 0.2 3.1e-21 76.2 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFM07633.1 - 5.9e-08 32.8 0.5 2.6e-07 30.7 0.3 1.8 2 0 0 2 2 2 1 short chain dehydrogenase Fringe PF02434.11 KFM07634.1 - 1.8e-120 400.8 0.0 2e-120 400.6 0.0 1.0 1 0 0 1 1 1 1 Fringe-like Glyco_transf_21 PF13506.1 KFM07634.1 - 0.016 14.4 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 21 Galactosyl_T PF01762.16 KFM07634.1 - 0.018 14.6 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 Galactosyltransferase Glyco_tranf_2_3 PF13641.1 KFM07634.1 - 0.023 14.4 0.0 0.039 13.7 0.0 1.5 1 1 0 1 1 1 0 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KFM07634.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 RPN7 PF10602.4 KFM07635.1 - 9.8e-75 249.8 0.7 1.7e-74 249.0 0.5 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 KFM07635.1 - 2.3e-17 63.2 1.2 8.7e-17 61.3 0.1 2.3 2 0 0 2 2 2 1 PCI domain TPR_11 PF13414.1 KFM07635.1 - 0.00069 19.2 0.1 0.24 11.0 0.0 2.9 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KFM07635.1 - 0.0037 17.0 4.6 0.15 12.0 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFM07635.1 - 0.077 12.6 5.2 0.16 11.6 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Dus PF01207.12 KFM07636.1 - 1.4e-56 191.6 0.0 2.5e-56 190.7 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 KFM07636.1 - 0.00058 19.1 0.0 0.00092 18.5 0.0 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein DUF702 PF05142.7 KFM07636.1 - 0.0029 17.8 10.4 0.0062 16.7 7.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF702) DHO_dh PF01180.16 KFM07636.1 - 0.024 13.6 0.0 0.093 11.6 0.0 1.8 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase Ribosomal_S14 PF00253.16 KFM07636.1 - 0.031 13.6 2.5 0.077 12.3 1.7 1.7 1 0 0 1 1 1 0 Ribosomal protein S14p/S29e TMP-TENI PF02581.12 KFM07636.1 - 0.04 13.0 0.1 0.085 11.9 0.0 1.5 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI ThiG PF05690.9 KFM07636.1 - 0.16 11.0 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG PEP-utilisers_N PF05524.8 KFM07638.1 - 0.0012 18.6 0.3 0.0012 18.6 0.2 1.0 1 0 0 1 1 1 1 PEP-utilising enzyme, N-terminal DivIC PF04977.10 KFM07638.1 - 0.0046 16.4 0.7 0.0048 16.3 0.5 1.2 1 0 0 1 1 1 1 Septum formation initiator TMF_DNA_bd PF12329.3 KFM07638.1 - 0.0065 16.2 2.0 0.0078 16.0 1.4 1.2 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding DUF3450 PF11932.3 KFM07638.1 - 0.016 14.4 1.1 0.018 14.3 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DMPK_coil PF08826.5 KFM07638.1 - 0.017 14.9 1.0 0.021 14.7 0.7 1.3 1 0 0 1 1 1 0 DMPK coiled coil domain like Med4 PF10018.4 KFM07638.1 - 0.021 14.2 0.6 0.021 14.2 0.4 1.1 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 bZIP_1 PF00170.16 KFM07638.1 - 0.031 14.2 1.0 0.037 13.9 0.7 1.2 1 0 0 1 1 1 0 bZIP transcription factor Med9 PF07544.8 KFM07638.1 - 0.04 13.6 0.3 0.051 13.3 0.2 1.2 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DivIVA PF05103.8 KFM07638.1 - 0.05 13.6 0.7 0.055 13.5 0.5 1.1 1 0 0 1 1 1 0 DivIVA protein NYD-SP28_assoc PF14775.1 KFM07638.1 - 0.056 13.1 0.6 0.056 13.1 0.4 1.6 1 1 1 2 2 2 0 Sperm tail C-terminal domain DUF904 PF06005.7 KFM07638.1 - 0.064 13.5 1.1 0.072 13.3 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF904) bZIP_2 PF07716.10 KFM07638.1 - 0.075 12.8 2.1 0.12 12.2 1.5 1.3 1 0 0 1 1 1 0 Basic region leucine zipper Microtub_assoc PF07989.6 KFM07638.1 - 0.076 12.8 0.6 0.093 12.5 0.4 1.2 1 0 0 1 1 1 0 Microtubule associated Atg14 PF10186.4 KFM07638.1 - 0.085 11.7 0.5 0.084 11.7 0.3 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF724 PF05266.9 KFM07638.1 - 0.11 12.1 1.5 0.12 11.9 1.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF724) FlaC_arch PF05377.6 KFM07638.1 - 0.12 12.2 0.9 0.2 11.6 0.6 1.5 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) HALZ PF02183.13 KFM07638.1 - 0.17 11.6 2.3 0.42 10.3 1.5 1.8 1 1 0 1 1 1 0 Homeobox associated leucine zipper MFS_1 PF07690.11 KFM07639.1 - 5.7e-39 133.8 42.1 4.2e-35 121.1 20.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KFM07639.1 - 0.00021 21.0 7.0 0.19 11.5 0.0 3.6 3 0 0 3 3 3 2 MFS_1 like family Pkinase PF00069.20 KFM07640.1 - 1.9e-38 132.1 0.0 2.4e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM07640.1 - 1.4e-17 63.5 0.0 1.8e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFM07640.1 - 9.7e-05 22.2 0.0 0.00067 19.4 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KFM07640.1 - 0.029 13.1 0.2 0.04 12.7 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 KFM07640.1 - 0.1 11.5 0.0 0.35 9.7 0.0 1.7 2 0 0 2 2 2 0 Kinase-like MyTH4 PF00784.12 KFM07641.1 - 1.7e-30 105.3 0.5 9.9e-29 99.6 0.1 2.6 2 0 0 2 2 2 1 MyTH4 domain FERM_M PF00373.13 KFM07641.1 - 2.7e-07 30.8 2.3 2.7e-07 30.7 0.1 2.1 2 0 0 2 2 2 1 FERM central domain CLASP_N PF12348.3 KFM07641.1 - 0.018 14.4 0.1 0.036 13.4 0.1 1.5 1 0 0 1 1 1 0 CLASP N terminal DEAD PF00270.24 KFM07642.1 - 3.6e-21 75.3 0.1 9.2e-21 74.0 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ5 PF06959.6 KFM07642.1 - 1.3e-20 73.9 12.5 3.3e-20 72.5 8.7 1.7 1 0 0 1 1 1 1 RecQ helicase protein-like 5 (RecQ5) Helicase_C PF00271.26 KFM07642.1 - 1.8e-17 62.9 0.0 2.9e-14 52.6 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 KFM07642.1 - 0.00032 20.5 0.6 0.0015 18.3 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF3593 PF12159.3 KFM07643.1 - 0.0021 17.8 0.0 0.0026 17.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3593) Shisa PF13908.1 KFM07643.1 - 0.01 16.0 2.0 0.01 16.0 1.4 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator IncA PF04156.9 KFM07643.1 - 0.012 15.2 0.5 0.016 14.8 0.3 1.1 1 0 0 1 1 1 0 IncA protein FAM163 PF15069.1 KFM07643.1 - 0.095 13.2 6.9 0.12 12.9 4.8 1.1 1 0 0 1 1 1 0 FAM163 family Herpes_LMP2 PF07415.6 KFM07643.1 - 0.14 10.6 2.8 0.14 10.6 1.9 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Corona_S2 PF01601.11 KFM07643.1 - 0.31 9.0 7.3 0.35 8.8 5.1 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Prominin PF05478.6 KFM07643.1 - 0.55 7.6 7.2 0.52 7.7 5.0 1.1 1 0 0 1 1 1 0 Prominin HCNGP PF07818.8 KFM07644.1 - 1.4e-37 127.6 1.3 2.5e-37 126.7 0.9 1.4 1 0 0 1 1 1 1 HCNGP-like protein DUF2051 PF09738.4 KFM07644.1 - 0.014 14.7 0.3 0.014 14.7 0.2 1.9 3 0 0 3 3 3 0 Double stranded RNA binding protein (DUF2051) Integrin_beta PF00362.13 KFM07645.1 - 1.6e-132 442.4 0.2 3e-132 441.5 0.2 1.4 1 0 0 1 1 1 1 Integrin, beta chain fn3 PF00041.16 KFM07645.1 - 1.3e-67 223.9 0.9 1.5e-17 63.4 0.1 4.5 4 0 0 4 4 4 4 Fibronectin type III domain Calx-beta PF03160.9 KFM07645.1 - 7.2e-16 57.9 0.3 2e-15 56.5 0.0 2.0 2 0 0 2 2 2 1 Calx-beta domain Integrin_B_tail PF07965.7 KFM07645.1 - 2.6e-15 56.6 8.7 2.6e-15 56.6 6.0 2.4 2 0 0 2 2 2 1 Integrin beta tail domain SEA PF01390.15 KFM07645.1 - 5.1e-05 22.9 0.0 0.00012 21.7 0.0 1.6 1 0 0 1 1 1 1 SEA domain EGF_2 PF07974.8 KFM07645.1 - 0.003 17.6 11.2 0.003 17.6 7.8 5.8 6 1 0 6 6 6 4 EGF-like domain GHMP_kinases_C PF08544.8 KFM07646.1 - 9.7e-15 54.5 0.0 2.2e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 KFM07646.1 - 1.1e-12 47.8 0.3 3e-12 46.4 0.2 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain Antimicrobial10 PF08105.6 KFM07646.1 - 0.12 11.9 0.2 0.29 10.7 0.2 1.6 1 0 0 1 1 1 0 Metchnikowin family DUF1681 PF07933.9 KFM07648.1 - 0.11 11.9 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1681) Histone PF00125.19 KFM07649.1 - 1.7e-33 114.5 0.2 2e-33 114.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KFM07649.1 - 6.2e-05 23.1 0.0 8.2e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 KFM07649.1 - 0.013 14.7 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CBFD_NFYB_HMF PF00808.18 KFM07649.1 - 0.029 14.4 0.0 0.04 13.9 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone zf-CCCH PF00642.19 KFM07650.1 - 2.4e-05 23.9 6.0 7.1e-05 22.3 0.7 7.0 8 0 0 8 8 8 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 KFM07650.1 - 0.00018 21.1 10.5 0.00018 21.1 7.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF3450 PF11932.3 KFM07650.1 - 0.0019 17.5 2.6 0.0029 16.9 1.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Fez1 PF06818.10 KFM07650.1 - 0.007 16.4 10.4 0.014 15.4 7.2 1.4 1 0 0 1 1 1 1 Fez1 Laminin_II PF06009.7 KFM07650.1 - 0.0079 15.9 0.9 0.016 14.9 0.6 1.4 1 0 0 1 1 1 1 Laminin Domain II DUF874 PF05917.6 KFM07650.1 - 0.033 13.0 5.7 0.051 12.4 3.9 1.2 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) WEMBL PF05701.6 KFM07650.1 - 0.088 11.2 10.2 0.14 10.6 7.1 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Mnd1 PF03962.10 KFM07650.1 - 0.12 12.0 11.9 1 8.9 7.0 2.5 2 1 0 2 2 2 0 Mnd1 family DUF2205 PF10224.4 KFM07650.1 - 0.72 9.4 4.3 0.25 10.9 0.7 2.0 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF947 PF06102.7 KFM07650.1 - 1.3 8.7 5.8 1.1 9.0 1.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF947) APG6 PF04111.7 KFM07650.1 - 1.5 7.7 11.4 2.5 7.0 7.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3584 PF12128.3 KFM07650.1 - 2.5 5.2 12.4 3.5 4.8 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) C2 PF00168.25 KFM07651.1 - 6.2e-38 128.5 0.0 2e-19 69.1 0.0 2.7 2 0 0 2 2 2 2 C2 domain Membr_traf_MHD PF10540.4 KFM07651.1 - 7.7e-16 58.1 11.0 6.1e-09 35.7 0.5 4.0 3 1 1 4 4 4 2 Munc13 (mammalian uncoordinated) homology domain WWbp PF10349.4 KFM07652.1 - 3e-20 73.2 17.1 3e-20 73.2 11.9 2.2 1 1 1 2 2 2 1 WW-domain ligand protein GRAM PF02893.15 KFM07652.1 - 3.4e-12 45.7 0.1 4.7e-12 45.2 0.1 1.2 1 0 0 1 1 1 1 GRAM domain Vps36_ESCRT-II PF11605.3 KFM07652.1 - 0.0079 15.9 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 bPH_3 PF14470.1 KFM07652.1 - 0.019 15.1 0.0 0.029 14.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial PH domain SPRY PF00622.23 KFM07653.1 - 8.4e-07 29.1 0.8 8.4e-07 29.1 0.6 2.2 3 0 0 3 3 3 1 SPRY domain PRY PF13765.1 KFM07653.1 - 0.00049 19.5 0.0 0.0017 17.8 0.0 1.9 1 0 0 1 1 1 1 SPRY-associated domain DRP PF06044.7 KFM07653.1 - 0.023 13.7 0.3 2.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Dam-replacing family DUF848 PF05852.6 KFM07653.1 - 0.24 11.2 4.8 0.43 10.4 2.5 1.9 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF1875 PF08961.5 KFM07653.1 - 0.57 9.4 2.9 0.55 9.5 0.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1875) PBP PF01161.15 KFM07654.1 - 1.8e-21 76.5 0.1 2.8e-21 75.8 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein ACOX PF01756.14 KFM07656.1 - 3e-65 219.1 0.7 4.6e-65 218.5 0.5 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 KFM07656.1 - 1.7e-27 96.2 0.3 7.8e-27 94.0 0.0 2.2 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 KFM07656.1 - 4.7e-07 29.2 0.1 1.1e-06 28.0 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 KFM07656.1 - 0.0038 17.3 0.0 0.014 15.5 0.0 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Ten1_2 PF15490.1 KFM07657.1 - 6.4e-42 141.8 0.0 7.1e-42 141.7 0.0 1.0 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit DUF960 PF06124.6 KFM07657.1 - 0.09 13.0 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Staphylococcal protein of unknown function (DUF960) Pkinase PF00069.20 KFM07658.1 - 4.7e-81 271.7 0.0 5.3e-81 271.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM07658.1 - 1.9e-38 132.0 0.0 2.2e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM07658.1 - 0.00065 18.7 0.1 0.022 13.7 0.0 2.2 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 KFM07658.1 - 0.0051 16.5 0.0 0.039 13.6 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KFM07658.1 - 0.089 11.8 0.0 0.18 10.8 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2322 PF10084.4 KFM07658.1 - 0.13 12.0 0.0 0.69 9.6 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2322) Plectin PF00681.15 KFM07659.1 - 5.3e-51 169.9 2.5 6.1e-15 54.4 0.1 7.9 6 1 2 8 8 8 6 Plectin repeat Spectrin PF00435.16 KFM07659.1 - 0.00038 20.7 10.0 0.00057 20.1 2.7 14.6 12 4 2 15 15 15 5 Spectrin repeat TPR_6 PF13174.1 KFM07660.1 - 0.0012 19.1 3.1 1.7 9.2 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFM07660.1 - 0.017 14.6 2.3 0.8 9.4 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 KFM07660.1 - 0.45 10.5 11.7 0.4 10.7 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 KFM07660.1 - 1.4 8.8 13.2 0.41 10.6 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 KFM07660.1 - 2 8.5 7.2 12 6.1 0.1 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 7tm_1 PF00001.16 KFM07661.1 - 5.8e-62 209.1 22.5 6.8e-62 208.9 15.6 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.4 KFM07661.1 - 4e-14 52.4 18.8 1.5e-12 47.2 13.1 2.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.4 KFM07661.1 - 2e-11 43.5 20.3 2.3e-11 43.3 14.1 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 KFM07661.1 - 6.3e-07 28.7 19.4 8.8e-07 28.3 13.4 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.4 KFM07661.1 - 0.00022 20.4 25.7 0.00092 18.3 17.6 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx SecG PF03840.9 KFM07661.1 - 0.0084 15.8 3.1 0.36 10.5 0.0 3.3 3 0 0 3 3 3 1 Preprotein translocase SecG subunit Herpes_US9 PF06072.6 KFM07661.1 - 0.095 12.5 0.4 0.57 10.0 0.3 2.3 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Flavi_capsid PF01003.14 KFM07661.1 - 0.1 12.1 0.1 0.2 11.1 0.1 1.5 1 0 0 1 1 1 0 Flavivirus capsid protein C Exo70 PF03081.10 KFM07662.1 - 3e-83 279.6 4.7 3e-83 279.6 3.3 1.9 2 0 0 2 2 2 1 Exo70 exocyst complex subunit GIT1_C PF12205.3 KFM07662.1 - 0.008 16.0 0.6 0.13 12.1 0.0 2.6 2 0 0 2 2 2 1 G protein-coupled receptor kinase-interacting protein 1 C term Scaffolding_pro PF11418.3 KFM07662.1 - 0.02 15.2 1.4 0.55 10.5 0.1 3.6 3 0 0 3 3 3 0 Phi29 scaffolding protein HTH_Crp_2 PF13545.1 KFM07662.1 - 0.068 12.9 0.1 0.73 9.6 0.0 2.4 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain COG5 PF10392.4 KFM07662.1 - 1.9 8.4 13.6 0.017 15.0 2.9 2.5 3 0 0 3 3 3 0 Golgi transport complex subunit 5 Fork_head PF00250.13 KFM07663.1 - 6.3e-38 128.7 0.1 1.3e-37 127.7 0.1 1.5 1 0 0 1 1 1 1 Fork head domain zf-C3HC4_3 PF13920.1 KFM07664.1 - 2e-14 52.9 9.2 3.8e-14 52.0 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM07664.1 - 1.5e-07 31.3 12.3 3e-07 30.3 8.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM07664.1 - 2.3e-05 24.1 12.0 5.7e-05 22.8 8.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KFM07664.1 - 0.00049 19.7 10.2 0.0014 18.3 7.1 1.8 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.1 KFM07664.1 - 0.0044 16.5 6.4 0.011 15.2 4.4 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 KFM07664.1 - 0.31 10.6 7.9 0.69 9.5 5.5 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.9 KFM07664.1 - 0.79 9.2 11.5 0.93 9.0 6.7 2.1 2 0 0 2 2 2 0 P-11 zinc finger T4_baseplate PF12322.3 KFM07665.1 - 0.002 17.4 0.1 0.0028 16.9 0.1 1.3 1 0 0 1 1 1 1 T4 bacteriophage base plate protein Cupin_4 PF08007.7 KFM07665.1 - 0.0092 15.2 2.0 0.015 14.6 1.4 1.2 1 0 0 1 1 1 1 Cupin superfamily protein DUF2217 PF10265.4 KFM07665.1 - 0.01 14.6 1.4 0.012 14.4 1.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) MerR-DNA-bind PF09278.6 KFM07665.1 - 0.024 15.0 3.6 0.024 15.0 2.5 3.7 3 1 1 4 4 4 0 MerR, DNA binding CorA PF01544.13 KFM07665.1 - 0.026 13.5 7.3 0.0079 15.2 1.8 1.9 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Het-C PF07217.6 KFM07665.1 - 0.042 12.0 4.1 0.015 13.5 0.9 1.5 2 0 0 2 2 2 0 Heterokaryon incompatibility protein Het-C Myb_DNA-bind_4 PF13837.1 KFM07665.1 - 0.043 13.9 0.1 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Bac_luciferase PF00296.15 KFM07665.1 - 0.069 12.2 0.1 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 Luciferase-like monooxygenase DUF948 PF06103.6 KFM07665.1 - 0.088 12.6 11.4 1.4 8.8 1.0 3.9 4 1 0 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF241 PF03087.9 KFM07665.1 - 1.6 8.1 8.6 3.9 6.9 0.1 2.9 2 1 0 3 3 3 0 Arabidopsis protein of unknown function YlbD_coat PF14071.1 KFM07665.1 - 1.6 8.7 6.7 19 5.3 0.0 3.2 2 1 1 3 3 3 0 Putative coat protein FUSC PF04632.7 KFM07665.1 - 1.7 7.0 14.0 0.092 11.1 4.4 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family Syntaxin-6_N PF09177.6 KFM07665.1 - 1.7 9.0 11.7 0.86 10.0 1.5 3.2 3 1 0 3 3 3 0 Syntaxin 6, N-terminal DUF2383 PF09537.5 KFM07665.1 - 2.5 8.4 10.2 10 6.3 1.5 3.9 3 3 0 4 4 4 0 Domain of unknown function (DUF2383) Spectrin PF00435.16 KFM07665.1 - 3.2 8.0 20.6 2.3 8.5 4.8 4.0 3 2 0 3 3 3 0 Spectrin repeat DUF2317 PF10079.4 KFM07665.1 - 3.9 5.9 14.3 0.58 8.7 3.6 2.6 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2317) Nudix_N PF12535.3 KFM07665.1 - 8.5 5.9 6.6 4.4 6.8 0.0 3.7 6 0 0 6 6 4 0 Hydrolase of X-linked nucleoside diphosphate N terminal Pribosyl_synth PF14572.1 KFM07666.1 - 1.4e-102 341.1 0.8 1.4e-102 341.1 0.6 1.5 2 0 0 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 KFM07666.1 - 5.3e-37 126.0 0.2 1.1e-36 125.0 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 KFM07666.1 - 0.00018 21.1 2.6 0.0011 18.6 1.2 2.6 2 1 0 2 2 2 1 Phosphoribosyl transferase domain Viral_env_E26 PF11050.3 KFM07666.1 - 0.11 11.6 0.1 0.25 10.5 0.1 1.5 1 0 0 1 1 1 0 Virus envelope protein E26 DAGK_cat PF00781.19 KFM07667.1 - 1.8e-25 88.8 0.0 2.7e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain UQ_con PF00179.21 KFM07668.1 - 2e-22 79.1 0.0 4.7e-22 77.9 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Acetyltransf_1 PF00583.19 KFM07669.1 - 1.2e-12 47.7 0.0 1.6e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFM07669.1 - 4.6e-07 29.9 0.0 7e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFM07669.1 - 0.0072 16.4 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2811 PF10929.3 KFM07669.1 - 0.056 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) Globin PF00042.17 KFM07670.1 - 4.5e-24 84.9 0.1 7.5e-24 84.2 0.1 1.4 1 0 0 1 1 1 1 Globin Glyco_transf_29 PF00777.13 KFM07671.1 - 2.6e-64 216.9 0.0 3e-64 216.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) JmjC PF02373.17 KFM07672.1 - 1.2e-29 102.8 0.0 2.4e-29 101.8 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 KFM07672.1 - 7.9e-21 74.6 0.1 1.3e-20 73.9 0.1 1.3 1 0 0 1 1 1 1 Cupin-like domain SR-25 PF10500.4 KFM07672.1 - 0.54 9.6 13.8 1.1 8.6 9.6 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.8 KFM07672.1 - 2.9 5.6 17.5 4 5.1 12.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Methyltransf_16 PF10294.4 KFM07673.1 - 3e-09 36.5 0.0 3.8e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase RRM_1 PF00076.17 KFM07674.1 - 4.9e-21 74.1 0.0 6.9e-21 73.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM07674.1 - 2.1e-16 59.6 0.0 3e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM07674.1 - 1.5e-11 43.9 0.0 2e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFM07674.1 - 0.028 14.2 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif Nup35_RRM_2 PF14605.1 KFM07674.1 - 0.071 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF936 PF06075.7 KFM07674.1 - 1.8 7.3 21.9 1.7 7.4 15.2 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Hid1 PF12722.2 KFM07674.1 - 3 5.4 8.5 3.4 5.2 5.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1777 PF08648.7 KFM07674.1 - 4.1 7.0 65.6 0.96 9.1 43.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) Apt1 PF10351.4 KFM07674.1 - 5.4 5.7 14.4 7.4 5.3 10.0 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain UNC-93 PF05978.11 KFM07675.1 - 5.8e-49 165.5 14.8 5.8e-49 165.5 10.2 3.2 4 0 0 4 4 4 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 KFM07675.1 - 1.9e-11 43.3 38.7 6.9e-09 34.8 17.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily OCIA PF07051.6 KFM07675.1 - 0.51 9.7 2.1 1.1 8.7 0.1 2.3 2 0 0 2 2 2 0 Ovarian carcinoma immunoreactive antigen (OCIA) IncA PF04156.9 KFM07675.1 - 3.5 7.1 4.7 37 3.8 0.0 2.7 2 0 0 2 2 2 0 IncA protein Glyco_transf_18 PF15024.1 KFM07676.1 - 2.4e-234 778.8 0.5 1.1e-233 776.7 0.4 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 18 PRELI PF04707.9 KFM07678.1 - 1.5e-51 174.0 0.5 2.2e-51 173.5 0.3 1.3 1 0 0 1 1 1 1 PRELI-like family CRAL_TRIO PF00650.15 KFM07678.1 - 2.2e-41 141.0 0.0 3.8e-41 140.2 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KFM07678.1 - 9.3e-09 35.2 0.3 8e-08 32.2 0.1 2.5 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KFM07678.1 - 0.0023 17.8 0.0 0.026 14.4 0.0 2.4 2 1 0 2 2 2 1 Divergent CRAL/TRIO domain Phage_fiber_2 PF03406.8 KFM07678.1 - 0.26 10.9 1.6 0.55 9.9 1.1 1.5 1 0 0 1 1 1 0 Phage tail fibre repeat Ras PF00071.17 KFM07679.1 - 8e-39 132.6 0.0 9.3e-39 132.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM07679.1 - 1.6e-19 70.5 0.0 2.3e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM07679.1 - 2.2e-09 36.8 0.0 2.5e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFM07679.1 - 1.8e-06 27.5 0.0 4.2e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KFM07679.1 - 1.3e-05 24.4 0.0 2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KFM07679.1 - 0.00046 20.1 0.0 0.00077 19.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KFM07679.1 - 0.0011 19.0 0.1 0.0086 16.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KFM07679.1 - 0.005 16.5 0.1 0.0088 15.7 0.1 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 KFM07679.1 - 0.0052 16.7 0.2 0.02 14.8 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 KFM07679.1 - 0.0056 15.8 0.0 0.011 14.8 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 NACHT PF05729.7 KFM07679.1 - 0.029 14.0 0.0 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 NACHT domain G-alpha PF00503.15 KFM07679.1 - 0.044 12.4 0.0 0.049 12.3 0.0 1.3 1 1 0 1 1 1 0 G-protein alpha subunit Viral_helicase1 PF01443.13 KFM07679.1 - 0.079 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Gtr1_RagA PF04670.7 KFM07679.1 - 0.086 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Guanylin PF02058.10 KFM07679.1 - 0.089 12.8 0.8 0.24 11.4 0.2 2.0 2 0 0 2 2 2 0 Guanylin precursor MobB PF03205.9 KFM07679.1 - 0.14 11.8 0.0 0.19 11.4 0.0 1.6 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B M_domain PF12938.2 KFM07680.1 - 2.4e-46 158.4 32.9 2.4e-46 158.4 22.8 9.3 5 3 3 9 9 9 1 M domain of GW182 Ago_hook PF10427.4 KFM07680.1 - 1.4e-16 60.8 30.3 1.4e-16 60.8 21.0 12.0 6 2 6 13 13 13 1 Argonaute hook UBA PF00627.26 KFM07680.1 - 1.2e-06 28.1 0.1 2.5e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain RRM_5 PF13893.1 KFM07680.1 - 2.9e-06 27.0 0.0 5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFM07680.1 - 0.00028 20.4 0.0 0.0005 19.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM07680.1 - 0.001 19.0 0.0 0.0024 17.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) THOC7 PF05615.8 KFM07680.1 - 0.22 11.7 3.6 0.39 10.9 2.5 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 Septin PF00735.13 KFM07681.1 - 1.1e-95 319.8 0.5 1.3e-95 319.6 0.3 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KFM07681.1 - 8.5e-08 32.1 0.2 2.7e-07 30.5 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KFM07681.1 - 5.5e-06 25.6 0.3 1.1e-05 24.6 0.2 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KFM07681.1 - 0.00053 19.8 1.8 0.34 10.7 0.4 2.3 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 KFM07681.1 - 0.0007 19.0 0.9 0.0044 16.4 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 KFM07681.1 - 0.0036 16.4 0.0 0.0067 15.5 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Ras PF00071.17 KFM07681.1 - 0.004 16.5 0.1 0.017 14.5 0.0 2.1 2 1 0 2 2 2 1 Ras family Miro PF08477.8 KFM07681.1 - 0.021 15.3 0.4 0.054 13.9 0.2 1.8 1 1 0 1 1 1 0 Miro-like protein ABC_tran PF00005.22 KFM07681.1 - 0.037 14.3 1.5 0.057 13.7 0.8 1.7 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.1 KFM07681.1 - 0.057 13.5 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.7 KFM07681.1 - 0.11 11.6 0.2 0.59 9.2 0.0 1.9 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region V-set PF07686.12 KFM07682.1 - 0.0048 16.7 0.2 0.01 15.6 0.0 1.7 2 0 0 2 2 2 1 Immunoglobulin V-set domain 7tm_1 PF00001.16 KFM07683.1 - 2.4e-48 164.5 24.7 3.3e-48 164.0 17.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.16 KFM07684.1 - 5.3e-19 68.3 4.9 6.1e-19 68.1 3.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM07684.1 - 0.00043 19.5 2.0 0.00055 19.1 1.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.4 KFM07684.1 - 0.00067 18.8 1.7 0.00093 18.4 1.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Anticodon_1 PF08264.8 KFM07684.1 - 0.036 13.8 0.5 0.073 12.8 0.2 1.6 1 1 0 1 1 1 0 Anticodon-binding domain of tRNA DUF1129 PF06570.6 KFM07684.1 - 0.052 12.8 0.2 0.081 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) 2OG-FeII_Oxy_3 PF13640.1 KFM07685.1 - 6.1e-20 71.5 0.5 9.6e-20 70.9 0.3 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KFM07685.1 - 1.8e-12 46.7 0.7 4.1e-12 45.5 0.5 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Oxygenase-NA PF09859.4 KFM07685.1 - 0.009 15.3 0.3 0.42 9.9 0.2 2.4 1 1 0 1 1 1 1 Oxygenase, catalysing oxidative methylation of damaged DNA 2OG-FeII_Oxy PF03171.15 KFM07685.1 - 0.0096 16.2 0.1 0.017 15.4 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_hydro_20 PF00728.17 KFM07686.1 - 3.8e-11 42.7 0.3 7e-11 41.8 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, catalytic domain DUF3279 PF11682.3 KFM07686.1 - 0.022 14.3 0.6 0.17 11.4 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3279) DUF4564 PF15169.1 KFM07687.1 - 2.6e-85 284.9 0.0 2.9e-85 284.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4564) UbiA PF01040.13 KFM07687.1 - 0.056 12.6 0.1 0.079 12.1 0.0 1.2 1 0 0 1 1 1 0 UbiA prenyltransferase family Fe_hyd_lg_C PF02906.9 KFM07688.1 - 2.3e-81 273.2 0.0 3.8e-81 272.4 0.0 1.3 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.12 KFM07688.1 - 2.3e-11 43.5 0.9 5e-11 42.4 0.1 2.0 2 0 0 2 2 2 1 Iron hydrogenase small subunit Fork_head PF00250.13 KFM07690.1 - 3.9e-41 138.9 0.2 6.3e-41 138.3 0.2 1.3 1 0 0 1 1 1 1 Fork head domain WD40 PF00400.27 KFM07691.1 - 2.2e-06 27.3 1.0 0.064 13.1 0.0 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF3761 PF12587.3 KFM07691.1 - 0.0024 17.9 0.1 0.0052 16.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3761) Me-amine-dh_H PF06433.6 KFM07691.1 - 0.023 13.3 0.1 4.6 5.7 0.1 2.5 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) CPSF_A PF03178.10 KFM07691.1 - 0.044 12.8 0.1 4.4 6.2 0.0 2.3 2 1 0 2 2 2 0 CPSF A subunit region DUF1513 PF07433.6 KFM07691.1 - 0.077 11.8 0.0 0.19 10.6 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1513) Ras PF00071.17 KFM07692.1 - 1.6e-42 144.6 0.0 2.3e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM07692.1 - 5.2e-13 49.5 0.0 8e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein SOCS_box PF07525.11 KFM07692.1 - 1.2e-09 37.8 1.7 2.2e-09 37.0 0.8 1.8 2 0 0 2 2 2 1 SOCS box Arf PF00025.16 KFM07692.1 - 1.8e-06 27.2 0.0 2.6e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFM07692.1 - 0.075 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Fructosamin_kin PF03881.9 KFM07693.1 - 2.3e-68 230.2 0.2 6.5e-68 228.8 0.1 1.6 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.18 KFM07693.1 - 1.1e-07 31.8 0.0 1.4e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KFM07693.1 - 0.11 11.8 0.0 3.9 6.7 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Fructosamin_kin PF03881.9 KFM07694.1 - 2.3e-68 230.2 0.0 6.9e-68 228.7 0.0 1.8 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.18 KFM07694.1 - 4.9e-10 39.5 0.0 7.6e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KFM07694.1 - 0.011 15.1 0.0 0.25 10.6 0.0 2.1 2 0 0 2 2 2 0 RIO1 family APH_6_hur PF04655.9 KFM07694.1 - 0.091 11.8 0.1 0.15 11.2 0.1 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase TFCD_C PF12612.3 KFM07695.1 - 7.8e-60 201.6 0.2 9.4e-59 198.0 0.0 2.7 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal HEAT_EZ PF13513.1 KFM07695.1 - 1.7e-05 25.1 12.3 0.26 11.8 0.0 7.5 6 3 2 8 8 8 2 HEAT-like repeat HEAT_2 PF13646.1 KFM07695.1 - 0.00054 20.1 1.9 0.2 11.9 0.0 4.5 2 2 2 4 4 4 2 HEAT repeats HEAT PF02985.17 KFM07695.1 - 0.0013 18.6 10.0 0.15 12.2 0.0 8.0 11 1 0 11 11 11 1 HEAT repeat HEAT_PBS PF03130.11 KFM07695.1 - 0.21 12.1 4.2 26 5.6 0.0 5.6 7 0 0 7 7 7 0 PBS lyase HEAT-like repeat zf-C2H2_7 PF15269.1 KFM07696.1 - 1.4e-36 124.0 11.3 4.9e-36 122.3 7.8 2.0 1 0 0 1 1 1 1 Zinc-finger zf-C2H2 PF00096.21 KFM07696.1 - 4.4 7.8 13.0 0.88 10.0 4.7 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type Glycos_transf_2 PF00535.21 KFM07697.1 - 3.5e-21 75.6 0.0 5.6e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.4 KFM07697.1 - 3.3e-09 36.2 0.0 5.3e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.1 KFM07697.1 - 2.6e-07 30.6 0.0 3.4e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 KFM07697.1 - 3.9e-05 23.8 0.0 0.0021 18.3 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 TIMP PF00965.12 KFM07698.1 - 0.007 15.9 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase NTR PF01759.16 KFM07698.1 - 0.03 13.8 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 UNC-6/NTR/C345C module 7tm_1 PF00001.16 KFM07700.1 - 6.8e-61 205.6 18.6 6.8e-61 205.6 12.9 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM07700.1 - 4e-07 29.4 21.6 8.9e-06 25.0 15.0 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Transglut_C PF00927.17 KFM07701.1 - 1.4e-35 121.5 0.3 4.7e-17 61.9 0.0 2.5 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_N PF00868.15 KFM07701.1 - 6.2e-29 100.4 0.1 1.3e-28 99.4 0.1 1.5 1 0 0 1 1 1 1 Transglutaminase family Transglut_core PF01841.14 KFM07701.1 - 3.6e-16 59.3 0.2 7.2e-16 58.3 0.2 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Transglut_C PF00927.17 KFM07702.1 - 1.2e-27 96.0 0.2 4.3e-13 49.2 0.0 2.4 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_N PF00868.15 KFM07702.1 - 5e-27 94.2 0.0 1.2e-26 93.1 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase family Transglut_core PF01841.14 KFM07702.1 - 1.2e-17 64.1 0.2 3.9e-17 62.4 0.2 1.9 1 0 0 1 1 1 1 Transglutaminase-like superfamily VIT_2 PF13757.1 KFM07702.1 - 0.11 11.9 0.0 0.28 10.6 0.0 1.6 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain Transglut_N PF00868.15 KFM07703.1 - 8.1e-28 96.8 0.0 1.8e-27 95.7 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase family Transglut_C PF00927.17 KFM07703.1 - 1.3e-26 92.7 0.3 9e-15 54.6 0.0 2.4 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.14 KFM07703.1 - 1.4e-15 57.4 0.4 3.1e-15 56.3 0.3 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Transglut_N PF00868.15 KFM07704.1 - 1.1e-31 109.2 0.0 2.1e-31 108.4 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase family Transglut_C PF00927.17 KFM07704.1 - 2.6e-28 98.2 0.0 4.8e-16 58.7 0.0 3.6 3 0 0 3 3 3 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.14 KFM07704.1 - 1.9e-18 66.7 0.8 3.7e-18 65.7 0.6 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily GCIP PF13324.1 KFM07705.1 - 1.6e-80 270.2 0.7 1.8e-80 270.0 0.5 1.0 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting AAA_12 PF13087.1 KFM07706.1 - 3.1e-39 134.4 0.0 1e-38 132.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KFM07706.1 - 2.5e-27 95.9 14.5 6.9e-27 94.5 5.7 2.8 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KFM07706.1 - 1e-09 38.0 0.0 3e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KFM07706.1 - 2.4e-07 30.5 0.4 0.00035 20.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.4 KFM07706.1 - 0.00041 19.4 0.9 0.0017 17.4 0.0 2.5 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 KFM07706.1 - 0.00045 20.0 0.0 0.0012 18.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.1 KFM07706.1 - 0.0011 18.4 1.0 0.0089 15.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 KFM07706.1 - 0.0028 16.9 0.1 0.011 14.9 0.0 2.0 2 0 0 2 2 2 1 PhoH-like protein DEAD PF00270.24 KFM07706.1 - 0.019 14.4 0.6 0.052 13.0 0.0 2.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_22 PF13401.1 KFM07706.1 - 0.04 14.0 1.1 0.78 9.8 0.0 3.1 2 0 0 2 2 2 0 AAA domain DEAD PF00270.24 KFM07707.1 - 6.6e-47 159.1 0.1 1.8e-44 151.2 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KFM07707.1 - 1.8e-25 88.5 0.1 6e-25 86.9 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KFM07707.1 - 0.00017 21.7 0.1 0.0011 19.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 KFM07707.1 - 0.00095 19.0 0.0 0.00095 19.0 0.0 3.5 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit PRK PF00485.13 KFM07707.1 - 0.2 11.2 2.5 0.56 9.7 0.0 2.7 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family LSM PF01423.17 KFM07708.1 - 0.056 12.9 0.0 0.077 12.5 0.0 1.1 1 0 0 1 1 1 0 LSM domain DUF3361 PF11841.3 KFM07709.1 - 1.4e-73 245.9 6.0 3e-73 244.8 4.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) ELMO_CED12 PF04727.8 KFM07709.1 - 4.2e-46 156.5 0.2 7.2e-46 155.8 0.2 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family GDE_C PF06202.9 KFM07709.1 - 0.14 10.8 0.9 21 3.6 0.0 3.1 3 0 0 3 3 3 0 Amylo-alpha-1,6-glucosidase TPT PF03151.11 KFM07710.1 - 6.8e-32 110.2 8.6 6.8e-32 110.2 5.9 2.1 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KFM07710.1 - 6.2e-05 22.0 17.6 8.6e-05 21.5 12.2 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 KFM07710.1 - 0.014 15.3 31.7 0.032 14.2 9.0 2.5 2 1 0 2 2 2 0 EamA-like transporter family DUF1129 PF06570.6 KFM07710.1 - 0.094 12.0 4.1 0.18 11.0 2.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) DUF3949 PF13133.1 KFM07710.1 - 0.15 12.3 0.2 25 5.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3949) EmrE PF13536.1 KFM07710.1 - 0.24 11.5 22.5 0.78 9.9 3.5 2.6 2 1 0 2 2 2 0 Multidrug resistance efflux transporter Cadherin PF00028.12 KFM07711.1 - 3.4e-83 274.0 12.8 3.6e-20 71.9 0.1 5.4 5 1 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.12 KFM07711.1 - 4.3e-43 146.8 0.2 9.6e-43 145.7 0.2 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.7 KFM07711.1 - 5.1e-06 25.9 0.1 0.69 9.5 0.0 4.5 4 0 0 4 4 4 2 Cadherin-like GRP PF07172.6 KFM07711.1 - 0.014 15.8 0.1 0.03 14.7 0.0 1.4 1 0 0 1 1 1 0 Glycine rich protein family TAS2R PF05296.8 KFM07711.1 - 0.057 12.3 0.1 0.089 11.6 0.0 1.2 1 0 0 1 1 1 0 Mammalian taste receptor protein (TAS2R) EphA2_TM PF14575.1 KFM07711.1 - 0.07 13.5 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ODV-E18 PF10717.4 KFM07711.1 - 0.12 11.7 0.2 0.29 10.6 0.1 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 7TM_GPCR_Srw PF10324.4 KFM07711.1 - 0.2 10.7 0.1 0.3 10.1 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw TNFR_c6 PF00020.13 KFM07712.1 - 1.4e-08 34.6 39.2 1.9e-05 24.5 7.2 4.6 4 0 0 4 4 4 3 TNFR/NGFR cysteine-rich region GCC2_GCC3 PF07699.8 KFM07712.1 - 0.0034 16.9 0.5 0.0034 16.9 0.4 4.5 4 1 1 5 5 5 2 GCC2 and GCC3 eIF-1a PF01176.14 KFM07712.1 - 0.12 11.8 0.1 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 Translation initiation factor 1A / IF-1 HGTP_anticodon PF03129.15 KFM07713.1 - 0.0013 18.6 0.0 0.0029 17.5 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain Macoilin PF09726.4 KFM07713.1 - 0.012 13.9 0.1 0.012 13.9 0.1 2.2 2 0 0 2 2 2 0 Transmembrane protein AA_permease PF00324.16 KFM07714.1 - 2e-51 174.8 22.2 2.9e-38 131.4 3.6 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 KFM07714.1 - 3.5e-17 62.0 23.2 1.3e-15 56.8 16.1 2.1 1 1 0 1 1 1 1 Amino acid permease Peptidase_M10 PF00413.19 KFM07715.1 - 3.2e-66 221.8 0.0 3.5e-65 218.4 0.0 2.4 2 1 0 2 2 2 1 Matrixin fn2 PF00040.14 KFM07715.1 - 2.7e-60 200.0 32.1 1.3e-20 73.0 4.0 3.6 3 0 0 3 3 3 3 Fibronectin type II domain Hemopexin PF00045.14 KFM07715.1 - 5.9e-25 86.7 6.9 2.5e-08 33.5 0.0 4.1 4 1 0 4 4 4 3 Hemopexin PG_binding_1 PF01471.13 KFM07715.1 - 6.6e-07 29.2 0.3 1.4e-06 28.1 0.2 1.6 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Reprolysin_3 PF13582.1 KFM07715.1 - 0.0071 16.8 0.1 0.043 14.3 0.0 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.19 KFM07715.1 - 0.03 13.7 0.0 2.2 7.6 0.0 2.2 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Reprolysin_5 PF13688.1 KFM07715.1 - 0.05 13.5 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KFM07715.1 - 0.066 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFM07715.1 - 0.18 11.8 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Homeobox_KN PF05920.6 KFM07716.1 - 1.3e-14 53.5 0.0 1.7e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KFM07716.1 - 3.2e-07 29.8 0.1 3.6e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 KFM07716.1 - 0.001 18.1 0.2 0.0022 17.0 0.1 1.6 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez HA PF03457.9 KFM07716.1 - 0.0046 17.0 0.1 0.0056 16.7 0.1 1.2 1 0 0 1 1 1 1 Helicase associated domain Phage_P2_GpE PF06528.7 KFM07716.1 - 0.11 11.9 0.1 0.22 11.0 0.1 1.5 1 0 0 1 1 1 0 Phage P2 GpE PCIF1_WW PF12237.3 KFM07717.1 - 5.6e-71 237.4 0.1 9e-71 236.7 0.1 1.3 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain WW PF00397.21 KFM07717.1 - 2.7e-08 33.5 0.5 5.6e-08 32.5 0.3 1.6 1 0 0 1 1 1 1 WW domain SR-25 PF10500.4 KFM07717.1 - 0.13 11.7 13.7 0.28 10.6 9.5 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein LBP_BPI_CETP_C PF02886.12 KFM07718.1 - 2.5e-60 203.6 0.2 4.4e-60 202.8 0.1 1.4 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.20 KFM07718.1 - 1.5e-30 105.6 0.3 4.5e-30 104.1 0.1 1.8 2 0 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain 7kD_coat PF02495.12 KFM07718.1 - 0.064 12.7 0.1 7.7 6.0 0.0 2.4 2 0 0 2 2 2 0 7kD viral coat protein Peptidase_S10 PF00450.17 KFM07719.1 - 1.5e-117 393.2 0.0 1.8e-117 393.0 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KFM07719.1 - 0.1 12.4 0.0 0.45 10.3 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFM07719.1 - 0.15 11.8 0.0 0.54 10.0 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family Neuralized PF07177.7 KFM07720.1 - 4.8e-22 77.6 0.0 8e-22 76.8 0.0 1.4 1 0 0 1 1 1 1 Neuralized SOCS_box PF07525.11 KFM07720.1 - 9.3e-11 41.4 0.7 1.8e-10 40.5 0.5 1.5 1 0 0 1 1 1 1 SOCS box Acyl_CoA_thio PF02551.10 KFM07721.1 - 7e-30 103.3 0.0 2.1e-27 95.3 0.0 2.1 2 0 0 2 2 2 2 Acyl-CoA thioesterase 4HBT_3 PF13622.1 KFM07721.1 - 4e-27 95.5 0.0 4.6e-27 95.3 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Glyco_trans_4_4 PF13579.1 KFM07721.1 - 0.06 13.4 0.0 0.081 13.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain EF-hand_1 PF00036.27 KFM07723.1 - 3e-30 101.1 23.2 1.8e-08 33.0 0.5 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KFM07723.1 - 4.5e-29 100.3 10.8 5e-16 58.5 3.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KFM07723.1 - 3e-26 90.7 19.0 3.9e-13 48.7 0.4 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 KFM07723.1 - 1.9e-24 83.2 14.8 9.8e-07 28.1 0.4 4.6 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KFM07723.1 - 2.5e-21 74.0 20.1 2e-06 26.9 0.2 4.5 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 KFM07723.1 - 2.9e-16 59.1 0.4 8.7e-08 31.9 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 KFM07723.1 - 5.3e-07 29.6 0.5 0.00026 21.0 0.4 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFM07723.1 - 1.5e-06 27.8 9.1 0.016 14.9 1.7 3.3 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand TerB PF05099.8 KFM07723.1 - 0.0011 18.7 4.0 0.03 14.0 1.1 2.1 1 1 1 2 2 2 2 Tellurite resistance protein TerB SpoVIF PF14069.1 KFM07723.1 - 0.0012 18.5 0.4 1.1 9.0 0.0 2.4 2 0 0 2 2 2 2 Stage VI sporulation protein F PTS_2-RNA PF01885.11 KFM07723.1 - 0.0068 15.7 0.0 0.025 13.9 0.0 1.7 2 0 0 2 2 2 1 RNA 2'-phosphotransferase, Tpt1 / KptA family FlgD PF03963.9 KFM07723.1 - 0.0099 15.9 0.1 1.5 8.9 0.0 2.4 2 0 0 2 2 2 1 Flagellar hook capping protein - N-terminal region HopW1-1 PF15457.1 KFM07723.1 - 0.077 12.0 0.2 3.1 6.7 0.0 2.0 1 1 1 2 2 2 0 Type III T3SS secreted effector HopW1-1/HopPmaA DUF3574 PF12098.3 KFM07723.1 - 0.13 11.8 0.1 0.36 10.4 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3574) DUF1456 PF07308.8 KFM07723.1 - 0.14 12.2 3.7 2.1 8.4 0.2 2.9 2 1 2 4 4 4 0 Protein of unknown function (DUF1456) Kunitz_BPTI PF00014.18 KFM07725.1 - 3.8e-17 62.2 13.5 3.8e-17 62.2 9.3 1.7 2 0 0 2 2 2 1 Kunitz/Bovine pancreatic trypsin inhibitor domain WAP PF00095.16 KFM07725.1 - 7.7e-06 25.7 11.9 7.7e-06 25.7 8.2 2.4 3 1 0 3 3 3 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' WAP PF00095.16 KFM07726.1 - 1.3e-23 82.6 61.0 1.9e-10 40.4 13.0 3.0 3 0 0 3 3 3 3 WAP-type (Whey Acidic Protein) 'four-disulfide core' WAP PF00095.16 KFM07727.1 - 2.8e-10 40.0 21.8 3.6e-10 39.6 10.9 2.1 2 0 0 2 2 2 2 WAP-type (Whey Acidic Protein) 'four-disulfide core' CTNNBL PF08216.6 KFM07728.1 - 7.8e-43 144.4 3.4 3e-42 142.5 2.4 2.1 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.18 KFM07728.1 - 0.00055 19.6 4.0 6.1 6.8 0.2 3.8 3 0 0 3 3 3 3 Armadillo/beta-catenin-like repeat DUF4020 PF13212.1 KFM07728.1 - 0.017 14.7 1.0 0.072 12.6 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4020) DUF262 PF03235.9 KFM07728.1 - 0.39 10.6 5.7 1.3 8.9 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF262 I-set PF07679.11 KFM07729.1 - 0.0052 16.6 0.1 0.008 16.0 0.1 1.5 1 1 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.12 KFM07729.1 - 0.13 12.1 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 Immunoglobulin V-set domain HEAT_2 PF13646.1 KFM07730.1 - 8.2e-05 22.8 9.2 0.011 16.0 0.2 4.6 5 0 0 5 5 5 2 HEAT repeats VHS PF00790.14 KFM07730.1 - 0.0032 17.1 3.4 0.19 11.3 0.0 4.5 4 1 0 4 4 4 1 VHS domain Vac14_Fab1_bd PF12755.2 KFM07730.1 - 0.0032 17.8 0.3 0.84 10.0 0.0 3.8 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 KFM07730.1 - 0.0059 16.5 17.0 12 6.3 0.0 7.9 7 0 0 7 7 7 2 HEAT repeat DUF493 PF04359.9 KFM07730.1 - 0.033 14.5 0.0 0.14 12.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF493) Transglut_C PF00927.17 KFM07731.1 - 6.8e-46 154.7 0.0 1e-23 83.4 0.0 2.7 3 0 0 3 3 3 2 Transglutaminase family, C-terminal ig like domain Transglut_N PF00868.15 KFM07731.1 - 3.9e-35 120.4 0.0 7.3e-35 119.5 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase family Transglut_core PF01841.14 KFM07731.1 - 1.4e-17 63.9 1.0 2.6e-17 63.0 0.7 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily CRAL_TRIO_2 PF13716.1 KFM07732.1 - 3.1e-07 30.4 0.0 5.5e-06 26.3 0.0 2.3 2 1 0 2 2 2 1 Divergent CRAL/TRIO domain Radical_SAM PF04055.16 KFM07734.1 - 3.5e-35 121.6 0.0 8.9e-35 120.3 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.15 KFM07734.1 - 5.8e-30 103.0 0.1 1.2e-29 102.0 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.15 KFM07734.1 - 2.4e-10 40.0 0.0 5e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 TRAM domain LBP_BPI_CETP_C PF02886.12 KFM07735.1 - 6.9e-26 90.9 0.5 1.7e-25 89.6 0.3 1.7 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.20 KFM07735.1 - 1e-23 83.4 1.8 1.2e-23 83.2 0.0 2.0 3 0 0 3 3 3 1 LBP / BPI / CETP family, N-terminal domain LBP_BPI_CETP_C PF02886.12 KFM07736.1 - 5.3e-20 71.6 0.6 8.1e-20 71.0 0.4 1.2 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP_C PF02886.12 KFM07737.1 - 9.4e-09 34.8 1.9 1.8e-08 33.8 0.9 1.8 1 1 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.20 KFM07737.1 - 3.6e-06 26.4 0.4 4.4e-05 22.8 0.1 2.4 1 1 1 2 2 2 1 LBP / BPI / CETP family, N-terminal domain LBP_BPI_CETP PF01273.20 KFM07738.1 - 2.1e-22 79.1 8.5 2.1e-22 79.1 5.9 2.1 2 1 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain LBP_BPI_CETP_C PF02886.12 KFM07738.1 - 9e-14 51.2 0.1 2.3e-13 49.9 0.1 1.7 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain EB1 PF03271.12 KFM07739.1 - 3.8e-17 62.0 0.8 1.6e-16 60.0 0.5 2.1 2 0 0 2 2 2 1 EB1-like C-terminal motif CH PF00307.26 KFM07739.1 - 1.4e-12 47.5 0.3 1.8e-11 44.0 0.1 2.0 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFM07739.1 - 0.03 13.9 0.0 0.085 12.5 0.0 1.7 2 0 0 2 2 2 0 CAMSAP CH domain HCaRG PF07258.9 KFM07740.1 - 5.5e-35 120.5 0.8 6.1e-35 120.3 0.6 1.0 1 0 0 1 1 1 1 HCaRG protein zf-H2C2 PF09337.5 KFM07741.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.5 1 1 0 1 1 1 0 His(2)-Cys(2) zinc finger PBP1_TM PF14812.1 KFM07742.1 - 0.15 12.3 2.2 0.19 12.0 0.1 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ASXH PF13919.1 KFM07743.1 - 8.6e-51 171.3 0.2 2e-50 170.1 0.1 1.6 1 0 0 1 1 1 1 Asx homology domain HARE-HTH PF05066.8 KFM07743.1 - 3.7e-14 52.8 0.0 1e-13 51.3 0.0 1.8 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain Kinesin PF00225.18 KFM07744.1 - 4.7e-121 403.5 0.9 4.7e-121 403.5 0.6 2.1 2 0 0 2 2 2 1 Kinesin motor domain O-FucT PF10250.4 KFM07745.1 - 1.7e-68 231.3 0.0 1.9e-68 231.1 0.0 1.0 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase zf-H2C2_2 PF13465.1 KFM07746.1 - 1.2e-25 88.4 51.6 1.3e-05 25.2 3.0 7.7 7 1 0 7 7 7 5 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM07746.1 - 1.7e-18 65.5 53.0 0.00053 20.1 1.7 7.5 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2 PF00096.21 KFM07746.1 - 5.5e-18 64.1 60.9 0.00013 22.0 1.2 7.4 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KFM07746.1 - 6.8e-05 22.6 0.2 6.8e-05 22.6 0.1 6.9 7 0 0 7 7 7 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM07746.1 - 0.0002 21.4 32.2 0.032 14.3 0.4 6.4 5 1 1 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 KFM07746.1 - 0.0026 17.8 32.1 0.019 15.1 4.6 4.8 1 1 5 6 6 6 3 Drought induced 19 protein (Di19), zinc-binding C1_1 PF00130.17 KFM07746.1 - 0.055 13.2 14.6 0.17 11.6 2.8 4.0 3 1 1 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-met PF12874.2 KFM07746.1 - 0.055 13.6 21.4 1.6 9.0 0.1 5.2 5 0 0 5 5 4 0 Zinc-finger of C2H2 type zf-met2 PF12907.2 KFM07746.1 - 0.067 13.1 0.2 0.067 13.1 0.2 4.2 4 1 1 5 5 4 0 Zinc-binding Equine_IAV_S2 PF06502.6 KFM07746.1 - 0.14 12.0 0.3 0.39 10.6 0.2 1.7 1 0 0 1 1 1 0 Equine infectious anaemia virus S2 protein zf-C2H2_2 PF12756.2 KFM07746.1 - 0.48 10.5 38.9 0.81 9.8 0.8 6.2 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) PyrI_C PF02748.10 KFM07746.1 - 1.4 8.4 12.9 0.7 9.3 0.2 4.2 4 1 1 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain FYDLN_acid PF09538.5 KFM07746.1 - 1.4 9.5 7.9 15 6.2 0.0 3.9 2 2 2 4 4 4 0 Protein of unknown function (FYDLN_acid) ADK_lid PF05191.9 KFM07746.1 - 3.2 7.4 13.7 1.7 8.3 0.2 3.7 4 0 0 4 4 4 0 Adenylate kinase, active site lid RRN7 PF11781.3 KFM07746.1 - 6.9 6.2 8.7 34 4.0 0.0 4.2 5 0 0 5 5 5 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-CHCC PF10276.4 KFM07746.1 - 6.9 6.6 16.1 12 5.8 0.5 4.1 4 0 0 4 4 4 0 Zinc-finger domain EMP70 PF02990.11 KFM07747.1 - 6.1e-229 760.7 13.4 7.8e-229 760.4 9.3 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 DUF4229 PF14012.1 KFM07747.1 - 0.38 10.6 0.0 0.38 10.6 0.0 4.4 5 0 0 5 5 5 0 Protein of unknown function (DUF4229) Pkinase_Tyr PF07714.12 KFM07748.1 - 1.2e-94 316.2 0.0 1.5e-94 315.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM07748.1 - 4.3e-49 166.9 0.0 5.5e-49 166.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 KFM07748.1 - 1e-24 86.1 0.0 1.9e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.23 KFM07748.1 - 1.7e-15 56.1 0.0 3.9e-15 54.9 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFM07748.1 - 1.7e-14 53.0 0.0 3.8e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFM07748.1 - 7.1e-11 41.4 0.0 1.7e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain APH PF01636.18 KFM07748.1 - 0.044 13.5 0.0 3.2 7.4 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family fn3 PF00041.16 KFM07749.1 - 8.1e-223 721.3 78.1 8.4e-12 45.0 0.3 34.8 34 2 0 34 34 34 32 Fibronectin type III domain Laminin_G_2 PF02210.19 KFM07749.1 - 1.8e-42 144.3 0.1 2.6e-20 72.7 0.0 2.9 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.18 KFM07749.1 - 3.5e-35 120.8 0.1 1.7e-16 60.3 0.0 2.6 2 0 0 2 2 2 2 Laminin G domain ChitinaseA_N PF08329.5 KFM07749.1 - 2.7e-10 40.1 12.6 1.5 8.5 0.0 13.5 15 1 1 16 16 16 1 Chitinase A, N-terminal domain SusE PF14292.1 KFM07749.1 - 2.1e-08 33.9 10.5 3.4 7.4 0.0 11.9 13 0 0 13 13 13 2 SusE outer membrane protein PhoD PF09423.5 KFM07749.1 - 0.023 13.2 2.0 10 4.5 0.0 5.6 5 1 1 6 6 6 0 PhoD-like phosphatase DUF2369 PF10179.4 KFM07749.1 - 0.067 12.2 3.7 6.2 5.8 0.0 5.7 7 0 0 7 7 7 0 Uncharacterised conserved protein (DUF2369) Arylsulfotrans PF05935.6 KFM07749.1 - 0.12 10.8 0.0 1.2 7.5 0.0 2.1 2 0 0 2 2 2 0 Arylsulfotransferase (ASST) BTB_2 PF02214.17 KFM07750.1 - 1e-12 48.0 0.0 1.9e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain WD40 PF00400.27 KFM07750.1 - 0.00041 20.1 2.2 1 9.3 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat Ion_trans_2 PF07885.11 KFM07751.1 - 1.1e-38 130.8 31.4 4.5e-19 67.9 10.7 4.0 3 1 1 4 4 4 3 Ion channel bZIP_Maf PF03131.12 KFM07751.1 - 0.0049 17.1 0.6 0.0093 16.2 0.4 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF872 PF05915.7 KFM07751.1 - 0.1 12.4 1.2 3.9 7.3 0.3 2.6 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF3139 PF11337.3 KFM07751.1 - 3 8.1 5.9 2.6 8.3 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) CENP-F_C_Rb_bdg PF10490.4 KFM07752.1 - 1.4e-17 62.7 0.0 2.4e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Rb-binding domain of kinetochore protein Cenp-F/LEK1 DUF2115 PF09888.4 KFM07752.1 - 0.49 10.4 3.2 0.33 11.0 0.6 1.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) V_ATPase_I PF01496.14 KFM07752.1 - 4.2 5.1 7.8 4.5 4.9 5.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Filament PF00038.16 KFM07753.1 - 0.0093 15.4 17.6 0.017 14.6 4.6 2.0 1 1 1 2 2 2 1 Intermediate filament protein Rota_NSP3 PF01665.11 KFM07753.1 - 0.084 11.8 8.1 0.096 11.6 5.6 1.0 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 AAA_32 PF13654.1 KFM07753.1 - 0.092 11.3 11.9 0.11 11.1 8.2 1.0 1 0 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.7 KFM07753.1 - 0.1 12.3 8.0 0.17 11.7 5.5 1.3 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.3 KFM07753.1 - 0.11 9.8 15.2 0.13 9.5 10.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Atg14 PF10186.4 KFM07753.1 - 0.12 11.2 15.3 0.13 11.1 10.6 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Spc7 PF08317.6 KFM07753.1 - 0.13 10.8 19.0 0.16 10.6 13.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein YdfA_immunity PF12127.3 KFM07753.1 - 0.13 11.0 0.8 0.15 10.9 0.5 1.1 1 0 0 1 1 1 0 SigmaW regulon antibacterial Mnd1 PF03962.10 KFM07753.1 - 0.18 11.4 14.7 0.24 11.0 10.2 1.1 1 0 0 1 1 1 0 Mnd1 family SusE PF14292.1 KFM07753.1 - 0.22 11.3 2.2 0.35 10.7 1.5 1.5 1 1 0 1 1 1 0 SusE outer membrane protein DUF4200 PF13863.1 KFM07753.1 - 0.24 11.3 22.6 0.51 10.2 15.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Syntaxin-6_N PF09177.6 KFM07753.1 - 0.27 11.6 11.0 0.17 12.3 1.3 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF1664 PF07889.7 KFM07753.1 - 0.27 11.0 11.2 0.63 9.8 3.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Cep57_MT_bd PF06657.8 KFM07753.1 - 0.28 11.1 17.6 0.71 9.8 1.6 2.4 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF842 PF05811.8 KFM07753.1 - 0.29 10.6 7.5 0.51 9.7 5.1 1.6 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF842) GrpE PF01025.14 KFM07753.1 - 0.42 10.1 14.9 0.66 9.4 10.3 1.3 1 0 0 1 1 1 0 GrpE BLOC1_2 PF10046.4 KFM07753.1 - 0.47 10.6 14.8 0.16 12.0 5.8 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATP-synt_B PF00430.13 KFM07753.1 - 0.55 10.0 13.9 0.91 9.3 9.5 1.5 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) FliD_N PF02465.13 KFM07753.1 - 0.63 10.4 8.0 0.15 12.4 1.8 2.3 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus CENP-F_leu_zip PF10473.4 KFM07753.1 - 0.72 9.6 25.8 1.3 8.8 14.6 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMEM192 PF14802.1 KFM07753.1 - 0.74 8.6 4.4 0.96 8.2 3.0 1.2 1 0 0 1 1 1 0 TMEM192 family Reo_sigmaC PF04582.7 KFM07753.1 - 0.74 8.9 3.1 0.84 8.7 2.2 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein HR1 PF02185.11 KFM07753.1 - 0.81 9.4 19.9 0.8 9.4 2.5 2.4 1 1 1 2 2 2 0 Hr1 repeat APG6 PF04111.7 KFM07753.1 - 1 8.3 18.1 1.4 7.8 12.6 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 YqgF PF14639.1 KFM07753.1 - 1.1 8.8 3.9 1.3 8.5 2.7 1.1 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 SlyX PF04102.7 KFM07753.1 - 1.2 9.6 13.9 0.096 13.0 0.8 2.2 1 1 0 2 2 2 0 SlyX RBD-FIP PF09457.5 KFM07753.1 - 1.2 8.9 11.0 0.15 11.8 3.1 2.5 1 1 2 3 3 3 0 FIP domain IncA PF04156.9 KFM07753.1 - 1.2 8.6 17.9 1.7 8.1 12.4 1.2 1 0 0 1 1 1 0 IncA protein DUF4250 PF14056.1 KFM07753.1 - 1.4 8.6 4.6 15 5.4 0.3 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4250) YlqD PF11068.3 KFM07753.1 - 1.6 8.8 15.0 2.8 7.9 10.4 1.5 1 1 0 1 1 1 0 YlqD protein Vfa1 PF08432.5 KFM07753.1 - 1.7 8.6 13.2 2.3 8.2 9.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 OmpH PF03938.9 KFM07753.1 - 1.9 8.4 13.1 2.5 8.0 9.1 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Tweety PF04906.8 KFM07753.1 - 1.9 6.7 5.0 2.3 6.5 3.5 1.1 1 0 0 1 1 1 0 Tweety TMF_DNA_bd PF12329.3 KFM07753.1 - 2.1 8.2 25.7 2.9 7.7 2.3 2.8 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF848 PF05852.6 KFM07753.1 - 2.2 8.1 13.8 3.9 7.2 9.4 1.4 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DUF4407 PF14362.1 KFM07753.1 - 2.2 7.1 7.3 2.7 6.8 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mit_KHE1 PF10173.4 KFM07753.1 - 2.5 7.9 5.0 3 7.6 3.5 1.1 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Fmp27_WPPW PF10359.4 KFM07753.1 - 3 6.1 13.8 2.7 6.3 8.1 1.6 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain RapA_C PF12137.3 KFM07753.1 - 3.3 6.4 15.1 6 5.5 10.4 1.4 1 1 0 1 1 1 0 RNA polymerase recycling family C-terminal Glyco_hydro_63 PF03200.11 KFM07753.1 - 3.8 5.2 7.1 4.3 5.0 4.9 1.0 1 0 0 1 1 1 0 Mannosyl oligosaccharide glucosidase Phage_Mu_Gam PF07352.7 KFM07753.1 - 4.3 6.8 13.3 35 3.8 9.2 2.2 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein FlaC_arch PF05377.6 KFM07753.1 - 4.9 7.1 11.8 0.71 9.8 1.5 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DivIVA PF05103.8 KFM07753.1 - 5.5 7.0 18.3 12 5.9 12.4 1.7 1 1 0 1 1 1 0 DivIVA protein DUF724 PF05266.9 KFM07753.1 - 6 6.4 19.2 16 5.0 13.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF3450 PF11932.3 KFM07753.1 - 6 6.0 11.0 16 4.6 7.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF3086 PF11285.3 KFM07753.1 - 6 5.5 7.5 13 4.4 5.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3086) Fib_alpha PF08702.5 KFM07753.1 - 6.3 6.9 12.0 9.1 6.3 8.3 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.10 KFM07753.1 - 6.5 5.8 14.3 7.5 5.6 9.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF342 PF03961.8 KFM07753.1 - 7.1 4.9 14.6 8 4.7 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) ACCA PF03255.9 KFM07753.1 - 8.9 5.8 11.9 5.3 6.5 5.5 1.9 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF16 PF01519.11 KFM07753.1 - 9 6.5 11.8 8.8 6.6 6.2 1.8 1 1 1 2 2 2 0 Protein of unknown function DUF16 Jnk-SapK_ap_N PF09744.4 KFM07753.1 - 9.3 6.2 20.0 30 4.5 13.8 1.7 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 CENP-F_N PF10481.4 KFM07754.1 - 1.9e-69 234.3 27.2 2.1e-69 234.2 18.8 1.0 1 0 0 1 1 1 1 Cenp-F N-terminal domain Reo_sigmaC PF04582.7 KFM07754.1 - 0.013 14.6 2.3 0.016 14.3 1.6 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Ax_dynein_light PF10211.4 KFM07754.1 - 0.016 15.0 12.6 0.016 15.0 8.8 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain IncA PF04156.9 KFM07754.1 - 0.024 14.2 25.5 0.028 14.0 17.7 1.0 1 0 0 1 1 1 0 IncA protein FlaC_arch PF05377.6 KFM07754.1 - 0.028 14.3 15.0 0.25 11.2 1.9 3.2 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) APG6 PF04111.7 KFM07754.1 - 0.034 13.1 18.8 0.041 12.9 13.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Filament PF00038.16 KFM07754.1 - 0.045 13.2 18.3 0.046 13.1 10.2 1.7 1 1 0 1 1 1 0 Intermediate filament protein GrpE PF01025.14 KFM07754.1 - 0.047 13.2 17.0 0.091 12.3 11.8 1.5 1 1 0 1 1 1 0 GrpE Herpes_UL6 PF01763.11 KFM07754.1 - 0.054 11.6 9.2 0.068 11.3 6.4 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like CENP-F_leu_zip PF10473.4 KFM07754.1 - 0.059 13.2 23.3 0.08 12.7 16.2 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.6 KFM07754.1 - 0.077 11.6 18.8 0.087 11.4 13.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TFIID-18kDa PF02269.11 KFM07754.1 - 0.11 12.3 2.4 0.13 12.0 1.0 1.6 1 1 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Nucleocapsid-N PF11030.3 KFM07754.1 - 0.11 12.2 1.1 0.13 12.0 0.8 1.1 1 0 0 1 1 1 0 Nucleocapsid protein N Tropomyosin_1 PF12718.2 KFM07754.1 - 0.22 11.3 25.6 3.1 7.6 17.3 2.0 1 1 0 1 1 1 0 Tropomyosin like DUF2381 PF09544.5 KFM07754.1 - 0.23 10.5 4.4 0.26 10.3 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) TPR_MLP1_2 PF07926.7 KFM07754.1 - 0.23 11.2 25.4 0.087 12.5 10.5 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4463 PF14703.1 KFM07754.1 - 0.29 11.6 6.8 0.43 11.1 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4463) GAS PF13851.1 KFM07754.1 - 0.32 10.1 22.8 0.52 9.4 15.8 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Macoilin PF09726.4 KFM07754.1 - 0.37 9.0 16.4 0.42 8.8 11.4 1.0 1 0 0 1 1 1 0 Transmembrane protein Bacillus_HBL PF05791.6 KFM07754.1 - 0.44 9.8 16.0 0.21 10.9 6.9 2.0 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF848 PF05852.6 KFM07754.1 - 0.46 10.3 15.7 0.92 9.3 10.4 1.7 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DUF1395 PF07160.7 KFM07754.1 - 0.5 9.8 11.4 0.66 9.4 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) PspA_IM30 PF04012.7 KFM07754.1 - 0.54 9.5 20.4 0.031 13.6 8.4 2.0 1 1 1 2 2 2 0 PspA/IM30 family IFT57 PF10498.4 KFM07754.1 - 0.63 8.7 17.9 0.7 8.5 12.4 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 TMCO5 PF14992.1 KFM07754.1 - 0.64 9.1 19.6 0.73 8.9 13.6 1.0 1 0 0 1 1 1 0 TMCO5 family DUF342 PF03961.8 KFM07754.1 - 0.64 8.3 13.9 0.76 8.1 9.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Exonuc_VII_L PF02601.10 KFM07754.1 - 0.65 9.1 15.0 0.75 8.9 10.4 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2205 PF10224.4 KFM07754.1 - 0.65 9.6 16.3 0.14 11.7 7.9 2.1 1 1 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) Prominin PF05478.6 KFM07754.1 - 0.65 7.4 7.4 0.72 7.3 5.1 1.1 1 0 0 1 1 1 0 Prominin Atg14 PF10186.4 KFM07754.1 - 0.74 8.7 20.7 1.1 8.0 14.4 1.3 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 YlqD PF11068.3 KFM07754.1 - 0.81 9.7 22.3 1.3 9.0 9.2 2.1 1 1 1 2 2 2 0 YlqD protein OmpH PF03938.9 KFM07754.1 - 0.96 9.3 24.5 1.9 8.4 17.0 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) bZIP_1 PF00170.16 KFM07754.1 - 1.3 9.0 22.1 0.99 9.4 4.9 3.0 1 1 2 3 3 3 0 bZIP transcription factor Cytochrom_B562 PF07361.6 KFM07754.1 - 1.4 9.3 12.0 14 6.1 5.0 2.7 1 1 1 2 2 2 0 Cytochrome b562 Striatin PF08232.7 KFM07754.1 - 1.5 9.1 19.4 5.5 7.2 13.4 1.8 1 1 0 1 1 1 0 Striatin family TMF_DNA_bd PF12329.3 KFM07754.1 - 1.9 8.3 29.0 7.4 6.4 13.1 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding 5_nucleotid PF05761.9 KFM07754.1 - 2 6.8 7.9 2.2 6.6 5.5 1.1 1 0 0 1 1 1 0 5' nucleotidase family HlyD PF00529.15 KFM07754.1 - 2.2 7.5 15.0 2.5 7.3 10.4 1.0 1 0 0 1 1 1 0 HlyD family secretion protein ADIP PF11559.3 KFM07754.1 - 2.3 8.0 25.8 3.2 7.6 13.9 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.1 KFM07754.1 - 2.6 6.8 11.1 3.6 6.4 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Borrelia_P83 PF05262.6 KFM07754.1 - 2.7 6.1 17.9 3 6.0 12.4 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF972 PF06156.8 KFM07754.1 - 2.7 8.3 17.4 2.5 8.4 6.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Mnd1 PF03962.10 KFM07754.1 - 2.8 7.5 20.1 5.4 6.6 14.0 1.5 1 1 0 1 1 1 0 Mnd1 family CENP-Q PF13094.1 KFM07754.1 - 2.9 7.9 23.9 16 5.5 16.6 1.9 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Pox_A_type_inc PF04508.7 KFM07754.1 - 3.2 7.7 14.1 14 5.7 1.5 4.6 4 1 0 4 4 4 0 Viral A-type inclusion protein repeat RRF_GI PF12614.3 KFM07754.1 - 3.2 7.5 11.0 2.1 8.2 5.4 2.0 1 1 1 2 2 2 0 Ribosome recycling factor Spc24 PF08286.6 KFM07754.1 - 3.3 7.4 20.2 1.7 8.3 6.1 2.1 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 DUF3573 PF12097.3 KFM07754.1 - 3.4 6.1 6.7 4 5.9 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) ATG16 PF08614.6 KFM07754.1 - 4.1 7.1 22.1 1.4e+02 2.1 2.0 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF641 PF04859.7 KFM07754.1 - 4.2 7.1 16.5 8.1 6.2 5.8 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Jnk-SapK_ap_N PF09744.4 KFM07754.1 - 4.5 7.2 20.0 18 5.3 13.8 1.8 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 AAA_13 PF13166.1 KFM07754.1 - 4.8 5.5 19.2 12 4.2 13.3 1.5 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.12 KFM07754.1 - 5.8 6.6 8.2 7.2 6.3 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF87 LRS4 PF10422.4 KFM07754.1 - 6.6 6.0 20.4 7.3 5.8 14.1 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 DUF1664 PF07889.7 KFM07754.1 - 6.6 6.5 12.8 11 5.8 1.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.5 KFM07754.1 - 6.8 6.8 16.4 13 5.8 11.4 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.14 KFM07754.1 - 7.2 4.3 12.6 8.6 4.0 8.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 KFM07754.1 - 7.2 6.1 26.5 5.2 6.6 2.5 3.1 1 1 2 3 3 3 0 Septum formation initiator NPV_P10 PF05531.7 KFM07754.1 - 7.9 6.8 12.7 0.99 9.6 2.8 2.4 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein COG2 PF06148.6 KFM07754.1 - 8.6 6.2 14.5 8.3 6.2 6.4 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CASP_C PF08172.7 KFM07754.1 - 8.9 5.2 16.9 3.2 6.7 7.7 2.2 1 1 1 2 2 2 0 CASP C terminal Y_phosphatase PF00102.22 KFM07755.1 - 5.1e-75 251.8 0.5 1.2e-74 250.6 0.3 1.7 1 0 0 1 1 1 1 Protein-tyrosine phosphatase FERM_M PF00373.13 KFM07755.1 - 5.8e-22 78.2 2.6 1.4e-21 76.9 0.2 2.5 2 0 0 2 2 2 1 FERM central domain FERM_N PF09379.5 KFM07755.1 - 7.3e-21 74.0 0.1 1.9e-20 72.6 0.1 1.8 1 0 0 1 1 1 1 FERM N-terminal domain FERM_C PF09380.5 KFM07755.1 - 7.1e-10 38.9 0.7 2e-09 37.5 0.5 1.8 1 0 0 1 1 1 1 FERM C-terminal PH-like domain DSPc PF00782.15 KFM07755.1 - 4.5e-05 23.0 0.0 0.00014 21.4 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFM07755.1 - 0.0019 18.4 0.3 0.0068 16.6 0.0 2.1 2 0 0 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KFM07755.1 - 0.15 12.1 2.5 0.46 10.5 0.0 2.9 3 0 0 3 3 3 0 Inositol hexakisphosphate IRK_N PF08466.5 KFM07755.1 - 0.59 10.0 0.0 0.59 10.0 0.0 2.8 3 1 0 3 3 3 0 Inward rectifier potassium channel N-terminal SET PF00856.23 KFM07756.1 - 1.5e-11 44.8 0.0 3.2e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 SET domain TPR_12 PF13424.1 KFM07756.1 - 2.2e-05 24.2 0.1 4.9e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFM07756.1 - 0.007 16.8 0.1 0.23 12.1 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFM07756.1 - 0.013 15.4 0.5 0.95 9.5 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 KFM07756.1 - 0.015 14.8 0.1 0.039 13.6 0.1 1.7 1 0 0 1 1 1 0 TPR repeat TPR_10 PF13374.1 KFM07756.1 - 0.061 13.2 0.1 0.17 11.9 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat RPN7 PF10602.4 KFM07756.1 - 0.1 11.9 1.4 2.2 7.6 0.0 3.0 2 1 0 3 3 3 0 26S proteasome subunit RPN7 TPR_6 PF13174.1 KFM07756.1 - 0.16 12.4 2.8 17 6.1 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat HPD PF05044.7 KFM07757.1 - 6.2e-88 292.4 1.9 1.1e-87 291.5 1.3 1.4 1 0 0 1 1 1 1 Homeo-prospero domain Metal_resist PF13801.1 KFM07757.1 - 0.025 14.5 10.9 0.018 15.0 5.9 2.0 2 0 0 2 2 2 0 Heavy-metal resistance NifQ PF04891.7 KFM07757.1 - 0.037 14.1 2.3 1.5 8.9 0.0 3.3 3 0 0 3 3 3 0 NifQ DUF3138 PF11336.3 KFM07757.1 - 0.14 10.2 0.8 7 4.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) DUF2968 PF11180.3 KFM07757.1 - 0.2 10.9 15.5 0.43 9.9 10.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF4613 PF15390.1 KFM07757.1 - 0.22 9.6 6.2 0.35 9.0 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF1640 PF07798.6 KFM07757.1 - 0.59 10.1 6.7 1.4 8.9 4.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF4407 PF14362.1 KFM07757.1 - 0.82 8.5 9.0 1.2 7.9 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF342 PF03961.8 KFM07757.1 - 1.2 7.4 4.1 1.9 6.8 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Nop25 PF09805.4 KFM07757.1 - 2 8.5 17.4 3.8 7.5 11.9 1.6 1 1 0 1 1 1 0 Nucleolar protein 12 (25kDa) FliD_N PF02465.13 KFM07757.1 - 3.6 7.9 6.9 61 4.0 5.1 2.6 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus IncA PF04156.9 KFM07757.1 - 5.2 6.6 11.4 9.4 5.7 7.9 1.3 1 0 0 1 1 1 0 IncA protein Pkinase PF00069.20 KFM07758.1 - 2e-27 96.0 0.0 2.5e-23 82.5 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain MIT PF04212.13 KFM07758.1 - 1.4e-20 72.9 1.3 2.6e-20 72.0 0.9 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Pkinase_Tyr PF07714.12 KFM07758.1 - 2.1e-12 46.6 0.0 1.9e-10 40.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase PX PF00787.19 KFM07758.1 - 2.5e-12 46.5 0.3 5.2e-12 45.5 0.2 1.4 1 0 0 1 1 1 1 PX domain Kinase-like PF14531.1 KFM07758.1 - 1.3e-05 24.2 0.0 2.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Exo_endo_phos PF03372.18 KFM07759.1 - 3.3e-24 86.2 0.0 5.4e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TatD_DNase PF01026.16 KFM07760.1 - 2.6e-44 151.3 0.0 2.9e-44 151.2 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Flexi_CP_N PF08358.5 KFM07760.1 - 0.012 15.3 0.0 0.05 13.3 0.0 2.0 2 0 0 2 2 2 0 Carlavirus coat Mis14 PF08641.7 KFM07761.1 - 2.1e-15 57.0 0.3 3.7e-15 56.2 0.2 1.4 1 0 0 1 1 1 1 Kinetochore protein Mis14 like bZIP_1 PF00170.16 KFM07762.1 - 1.5e-13 50.4 12.3 1.9e-13 50.1 8.5 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFM07762.1 - 2.7e-10 39.9 13.3 3.3e-10 39.6 9.2 1.1 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KFM07762.1 - 1.8e-09 37.7 9.2 2.3e-09 37.4 6.4 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor HALZ PF02183.13 KFM07762.1 - 1.7e-05 24.4 2.6 3.2e-05 23.5 1.8 1.6 1 0 0 1 1 1 1 Homeobox associated leucine zipper HAP1_N PF04849.8 KFM07762.1 - 0.0016 17.4 5.7 0.0017 17.4 4.0 1.0 1 0 0 1 1 1 1 HAP1 N-terminal conserved region DivIC PF04977.10 KFM07762.1 - 0.0054 16.1 4.0 0.0076 15.7 2.8 1.4 1 0 0 1 1 1 1 Septum formation initiator DivIVA PF05103.8 KFM07762.1 - 0.0072 16.3 1.3 0.0072 16.3 0.9 1.9 1 1 1 2 2 2 1 DivIVA protein Macoilin PF09726.4 KFM07762.1 - 0.0073 14.6 3.2 0.0074 14.6 2.2 1.0 1 0 0 1 1 1 1 Transmembrane protein DASH_Spc19 PF08287.6 KFM07762.1 - 0.0091 15.6 0.1 0.0091 15.6 0.0 1.9 1 1 1 2 2 2 1 Spc19 BLOC1_2 PF10046.4 KFM07762.1 - 0.011 15.8 0.9 0.015 15.4 0.6 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TLE_N PF03920.10 KFM07762.1 - 0.011 15.5 2.1 0.013 15.2 1.5 1.2 1 0 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain TPD52 PF04201.10 KFM07762.1 - 0.011 15.4 4.2 0.011 15.4 2.9 1.3 1 1 0 1 1 1 0 Tumour protein D52 family TMF_DNA_bd PF12329.3 KFM07762.1 - 0.015 15.1 9.7 0.019 14.7 6.7 1.3 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF3450 PF11932.3 KFM07762.1 - 0.015 14.5 1.3 0.016 14.5 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF2681 PF10883.3 KFM07762.1 - 0.026 14.7 1.2 0.026 14.7 0.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) Rootletin PF15035.1 KFM07762.1 - 0.03 14.3 6.6 0.04 13.9 4.6 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion SYCE1 PF15233.1 KFM07762.1 - 0.034 14.0 6.5 0.025 14.5 3.5 1.5 1 1 0 1 1 1 0 Synaptonemal complex central element protein 1 DUF342 PF03961.8 KFM07762.1 - 0.036 12.4 4.0 0.039 12.3 2.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Borrelia_P83 PF05262.6 KFM07762.1 - 0.038 12.2 1.9 0.038 12.2 1.3 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Nsp1_C PF05064.8 KFM07762.1 - 0.039 13.5 0.5 0.05 13.2 0.3 1.2 1 0 0 1 1 1 0 Nsp1-like C-terminal region AAA_13 PF13166.1 KFM07762.1 - 0.039 12.4 4.5 0.042 12.3 3.1 1.0 1 0 0 1 1 1 0 AAA domain DUF4200 PF13863.1 KFM07762.1 - 0.039 13.8 9.2 0.062 13.2 6.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Phlebovirus_NSM PF07246.6 KFM07762.1 - 0.046 12.8 2.2 0.047 12.8 1.6 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Prominin PF05478.6 KFM07762.1 - 0.057 10.9 1.0 0.062 10.8 0.7 1.0 1 0 0 1 1 1 0 Prominin Ribosomal_L30_N PF08079.7 KFM07762.1 - 0.076 13.0 10.1 0.1 12.6 7.0 1.2 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain TMCO5 PF14992.1 KFM07762.1 - 0.081 12.0 4.8 0.098 11.7 3.3 1.1 1 0 0 1 1 1 0 TMCO5 family APG6 PF04111.7 KFM07762.1 - 0.085 11.8 6.1 0.097 11.6 4.2 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4140 PF13600.1 KFM07762.1 - 0.091 13.2 4.7 0.12 12.7 3.2 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) NYD-SP28_assoc PF14775.1 KFM07762.1 - 0.097 12.3 0.8 0.22 11.2 0.3 1.8 1 1 0 1 1 1 0 Sperm tail C-terminal domain DUF1515 PF07439.6 KFM07762.1 - 0.098 12.4 1.0 0.13 12.0 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Tnp_P_element PF12017.3 KFM07762.1 - 0.1 11.8 0.8 0.11 11.7 0.6 1.2 1 0 0 1 1 1 0 Transposase protein Jnk-SapK_ap_N PF09744.4 KFM07762.1 - 0.12 12.4 7.6 0.13 12.2 5.3 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 CNPase PF05881.7 KFM07762.1 - 0.13 11.6 0.3 0.15 11.4 0.2 1.2 1 0 0 1 1 1 0 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) DUF1465 PF07323.7 KFM07762.1 - 0.13 11.8 2.4 0.15 11.6 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) ADIP PF11559.3 KFM07762.1 - 0.15 12.0 9.6 0.19 11.6 6.6 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding RNA_pol_Rpb1_6 PF04992.9 KFM07762.1 - 0.15 11.7 2.4 0.16 11.6 1.7 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 6 TerB PF05099.8 KFM07762.1 - 0.15 11.7 2.0 0.19 11.4 1.4 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TerB DUF972 PF06156.8 KFM07762.1 - 0.16 12.3 5.5 0.22 11.8 3.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF972) GAS PF13851.1 KFM07762.1 - 0.16 11.1 9.2 0.21 10.7 6.3 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Seryl_tRNA_N PF02403.17 KFM07762.1 - 0.17 11.9 6.8 0.22 11.5 4.7 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 KFM07762.1 - 0.17 11.4 8.4 0.23 11.0 5.8 1.2 1 0 0 1 1 1 0 IncA protein Mnd1 PF03962.10 KFM07762.1 - 0.19 11.3 6.8 0.24 11.0 4.7 1.1 1 0 0 1 1 1 0 Mnd1 family DUF2009 PF09418.5 KFM07762.1 - 0.19 10.4 1.3 0.21 10.3 0.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) Vps5 PF09325.5 KFM07762.1 - 0.31 10.2 7.5 0.35 10.0 5.2 1.1 1 0 0 1 1 1 0 Vps5 C terminal like TMF_TATA_bd PF12325.3 KFM07762.1 - 0.33 10.7 7.6 0.18 11.5 3.1 1.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding AAA_11 PF13086.1 KFM07762.1 - 0.34 10.4 2.4 0.38 10.2 1.7 1.0 1 0 0 1 1 1 0 AAA domain CCDC92 PF14916.1 KFM07762.1 - 0.35 10.5 4.1 0.54 9.8 2.1 1.9 1 1 0 1 1 1 0 Coiled-coil domain of unknown function DUF904 PF06005.7 KFM07762.1 - 0.38 11.0 6.4 0.65 10.3 4.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Tho2 PF11262.3 KFM07762.1 - 0.46 9.4 3.1 0.53 9.2 2.1 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF3584 PF12128.3 KFM07762.1 - 0.47 7.7 6.1 0.55 7.4 4.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF2514 PF10721.4 KFM07762.1 - 0.51 10.0 5.0 0.61 9.7 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) V_ATPase_I PF01496.14 KFM07762.1 - 0.63 7.8 2.9 0.67 7.7 2.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATG16 PF08614.6 KFM07762.1 - 0.72 9.6 12.0 1.8 8.3 8.4 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF3552 PF12072.3 KFM07762.1 - 0.89 8.7 10.3 1.1 8.4 7.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF1640 PF07798.6 KFM07762.1 - 1.1 9.3 6.7 1.3 9.0 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) TMPIT PF07851.8 KFM07762.1 - 1.1 8.3 3.3 1.2 8.1 2.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF4094 PF13334.1 KFM07762.1 - 1.1 9.6 3.7 1.9 8.8 2.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) CENP-Q PF13094.1 KFM07762.1 - 1.3 8.9 9.5 2 8.4 6.6 1.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit OPA3 PF07047.7 KFM07762.1 - 1.6 8.5 5.2 2 8.2 3.6 1.3 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) RRF PF01765.14 KFM07762.1 - 2.1 7.7 9.3 2.7 7.4 6.4 1.1 1 0 0 1 1 1 0 Ribosome recycling factor CHD5 PF04420.9 KFM07762.1 - 2.5 7.7 4.9 22 4.6 3.1 2.1 1 1 1 2 2 2 0 CHD5-like protein Spc24 PF08286.6 KFM07762.1 - 3 7.5 7.1 7.6 6.2 4.9 1.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Bap31 PF05529.7 KFM07762.1 - 5.1 6.5 8.2 6.1 6.2 5.7 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Spt5_N PF11942.3 KFM07762.1 - 6.9 7.3 10.9 9.1 6.9 7.2 1.4 1 1 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Med21 PF11221.3 KFM07762.1 - 7.5 6.5 9.2 1 9.3 3.4 1.7 1 1 1 2 2 2 0 Subunit 21 of Mediator complex bZIP_1 PF00170.16 KFM07763.1 - 1.4e-11 44.1 19.6 2.8e-11 43.1 13.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFM07763.1 - 1e-10 41.2 18.9 1.6e-10 40.6 13.1 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KFM07763.1 - 7.6e-08 32.5 7.9 7.6e-08 32.5 5.5 1.6 2 0 0 2 2 2 1 bZIP Maf transcription factor SNAPc19 PF15497.1 KFM07763.1 - 0.0022 18.1 1.5 0.0022 18.1 1.0 2.0 2 1 0 2 2 2 1 snRNA-activating protein complex subunit 19, SNAPc subunit 19 AOX PF01786.12 KFM07763.1 - 0.018 14.4 0.2 0.021 14.2 0.1 1.2 1 0 0 1 1 1 0 Alternative oxidase Vps51 PF08700.6 KFM07763.1 - 0.075 12.8 2.5 0.17 11.7 1.7 1.6 1 0 0 1 1 1 0 Vps51/Vps67 DivIC PF04977.10 KFM07763.1 - 0.077 12.4 6.6 0.15 11.6 4.5 1.5 1 0 0 1 1 1 0 Septum formation initiator Macoilin PF09726.4 KFM07763.1 - 0.39 8.9 10.8 0.49 8.6 7.5 1.0 1 0 0 1 1 1 0 Transmembrane protein V_ATPase_I PF01496.14 KFM07763.1 - 0.45 8.2 3.9 0.51 8.1 2.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc24 PF08286.6 KFM07763.1 - 1.5 8.5 8.3 1.4 8.5 4.8 1.7 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Ribosomal_L6e PF01159.14 KFM07763.1 - 1.6 9.0 7.7 4.2 7.6 5.3 1.6 1 1 1 2 2 2 0 Ribosomal protein L6e Seryl_tRNA_N PF02403.17 KFM07763.1 - 3 7.8 13.1 4.9 7.2 9.1 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 KFM07763.1 - 3.7 7.1 7.5 5.4 6.5 5.2 1.4 1 0 0 1 1 1 0 IncA protein Cyt-b5 PF00173.23 KFM07765.1 - 8.3e-08 31.9 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TMEM206 PF15122.1 KFM07766.1 - 6.2e-175 580.1 3.1 7.2e-175 579.9 2.1 1.0 1 0 0 1 1 1 1 TMEM206 protein family B56 PF01603.15 KFM07767.1 - 4.9e-177 588.6 9.6 5.8e-177 588.3 6.6 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Cytochrom_B561 PF03188.11 KFM07767.1 - 0.043 13.6 0.3 0.071 12.9 0.2 1.4 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 WD40 PF00400.27 KFM07770.1 - 1.1e-35 120.2 10.7 9e-10 38.0 0.2 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat HEAT_2 PF13646.1 KFM07771.1 - 2.9e-05 24.2 5.5 0.46 10.7 0.1 4.6 4 1 0 4 4 4 2 HEAT repeats TPR_6 PF13174.1 KFM07771.1 - 0.0026 18.0 1.4 2.5 8.7 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFM07771.1 - 0.19 11.6 0.5 10 6.3 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat FANCI_S2 PF14676.1 KFM07771.1 - 0.3 10.9 10.1 0.49 10.2 0.5 3.5 3 0 0 3 3 3 0 FANCI solenoid 2 Acyltransferase PF01553.16 KFM07772.1 - 1.2e-07 31.2 0.0 1.9e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Pkinase PF00069.20 KFM07773.1 - 1.6e-54 184.7 0.1 5.9e-54 182.9 0.0 1.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM07773.1 - 4.8e-39 134.0 0.8 1.5e-38 132.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM07773.1 - 8.5e-09 34.7 0.0 1.6e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFM07773.1 - 0.0017 18.1 3.5 0.032 13.9 0.0 2.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family NCD1 PF04904.8 KFM07773.1 - 0.043 13.5 0.0 0.19 11.4 0.0 2.0 1 1 1 2 2 2 0 NAB conserved region 1 (NCD1) DUF4355 PF14265.1 KFM07773.1 - 0.044 13.7 9.3 0.11 12.4 6.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) DUF3552 PF12072.3 KFM07773.1 - 0.34 10.0 15.1 0.68 9.1 10.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) RD3 PF14473.1 KFM07775.1 - 1.4e-50 170.1 3.9 1.9e-50 169.7 2.7 1.2 1 0 0 1 1 1 1 RD3 protein DUF2309 PF10070.4 KFM07775.1 - 0.023 12.8 0.8 0.029 12.4 0.6 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) Peptidase_S28 PF05577.7 KFM07775.1 - 0.047 12.2 0.1 0.058 11.9 0.1 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 MATH PF00917.21 KFM07776.1 - 3.6e-23 82.0 0.0 9.1e-23 80.7 0.0 1.8 1 0 0 1 1 1 1 MATH domain zf-TRAF PF02176.13 KFM07776.1 - 1.4e-22 79.8 25.0 7e-15 55.1 4.1 4.2 3 1 1 4 4 3 2 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 KFM07776.1 - 2.3e-06 27.5 6.0 2.3e-06 27.5 4.2 4.7 4 1 0 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM07776.1 - 1.2e-05 24.9 5.8 1.2e-05 24.9 4.0 4.4 4 1 1 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFM07776.1 - 5.8e-05 22.8 5.8 5.8e-05 22.8 4.0 3.6 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KFM07776.1 - 0.00048 19.8 6.6 0.00048 19.8 4.6 3.6 3 1 0 3 3 2 1 Ring finger domain zf-RING_5 PF14634.1 KFM07776.1 - 0.002 17.8 6.2 0.002 17.8 4.3 4.6 3 1 1 4 4 2 1 zinc-RING finger domain zf-RING_6 PF14835.1 KFM07776.1 - 0.0096 15.6 2.4 0.0096 15.6 1.6 2.5 1 1 1 2 2 2 1 zf-RING of BARD1-type protein DUF4279 PF14106.1 KFM07776.1 - 0.036 13.9 4.4 4 7.3 0.5 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4279) Tropomyosin_1 PF12718.2 KFM07776.1 - 3 7.6 13.0 6.9 6.5 9.0 1.7 1 1 0 1 1 1 0 Tropomyosin like DUF3734 PF12536.3 KFM07776.1 - 5.4 7.1 6.3 16 5.6 0.9 2.6 1 1 1 2 2 2 0 Patatin phospholipase Myb_DNA-binding PF00249.26 KFM07777.1 - 3.1e-18 65.5 0.0 8e-10 38.6 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFM07777.1 - 7.6e-06 25.9 2.3 0.0041 17.2 0.0 3.3 3 0 0 3 3 3 2 Myb-like DNA-binding domain ELM2 PF01448.19 KFM07777.1 - 0.00036 21.1 0.0 0.0015 19.1 0.0 2.1 1 0 0 1 1 1 1 ELM2 domain MBOAT PF03062.14 KFM07778.1 - 1.3e-39 136.2 23.6 1.8e-39 135.7 16.3 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family SERTA PF06031.8 KFM07779.1 - 9.3e-17 60.0 0.2 1.5e-16 59.3 0.2 1.4 1 0 0 1 1 1 1 SERTA motif CAF-1_p150 PF11600.3 KFM07779.1 - 2.1 7.6 7.3 4.3 6.6 5.0 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF508 PF04370.7 KFM07779.1 - 3.9 7.0 14.3 9.9 5.7 9.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF508) C2 PF00168.25 KFM07780.1 - 8e-20 70.4 0.1 7.2e-12 44.9 0.0 2.2 2 0 0 2 2 2 2 C2 domain Bcr-Abl_Oligo PF09036.5 KFM07780.1 - 0.026 14.4 0.0 0.092 12.7 0.0 1.9 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain PI3K_C2 PF00792.19 KFM07780.1 - 0.08 12.7 0.1 0.21 11.3 0.1 1.7 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 DUF1253 PF06862.7 KFM07781.1 - 1.9e-166 553.9 4.6 2.5e-166 553.5 3.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) Glyco_hydro_14 PF01373.12 KFM07781.1 - 0.087 11.5 0.4 0.53 8.9 0.0 2.0 2 0 0 2 2 2 0 Glycosyl hydrolase family 14 Ribosomal_S10 PF00338.17 KFM07782.1 - 9.9e-24 83.0 0.2 1.3e-23 82.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e ELM2 PF01448.19 KFM07783.1 - 1.1e-11 45.2 0.1 1.1e-11 45.2 0.0 3.2 2 0 0 2 2 2 1 ELM2 domain zf-C2H2 PF00096.21 KFM07783.1 - 3.4e-06 27.0 7.6 0.055 13.8 0.2 4.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KFM07783.1 - 4.6e-05 23.1 7.3 0.00097 18.9 0.1 2.9 2 1 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KFM07783.1 - 0.00011 22.2 5.3 0.15 12.4 0.4 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger Myb_DNA-binding PF00249.26 KFM07783.1 - 0.00027 20.9 0.2 0.00064 19.7 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-C2H2_jaz PF12171.3 KFM07783.1 - 0.0072 16.4 2.3 0.52 10.5 0.5 3.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM07783.1 - 0.0096 16.0 3.2 0.06 13.5 0.1 3.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KFM07783.1 - 0.037 14.1 0.0 0.037 14.1 0.0 3.9 3 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 KFM07783.1 - 1 9.8 11.7 5 7.5 0.6 4.8 5 0 0 5 5 5 0 Zinc-finger double domain Tetraspannin PF00335.15 KFM07784.1 - 1.8e-43 148.4 10.6 4e-43 147.2 7.4 1.5 1 1 0 1 1 1 1 Tetraspanin family DUF161 PF02588.10 KFM07784.1 - 9.3 6.6 11.1 3.9 7.8 0.1 3.3 3 1 1 4 4 4 0 Uncharacterized BCR, YitT family COG1284 TBCC PF07986.7 KFM07786.1 - 2.1e-42 143.3 0.1 2.4e-42 143.1 0.1 1.0 1 0 0 1 1 1 1 Tubulin binding cofactor C GLTSCR1 PF15249.1 KFM07787.1 - 1.3e-32 112.1 1.4 3.3e-32 110.8 0.9 1.8 1 0 0 1 1 1 1 Glioma tumor suppressor candidate region PIP49_C PF12260.3 KFM07789.1 - 9.3e-12 44.7 0.0 1.6e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 SopE_GEF PF07487.8 KFM07789.1 - 0.03 14.2 0.0 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 SopE GEF domain WD40 PF00400.27 KFM07790.1 - 2.5e-27 93.6 21.5 3.3e-05 23.5 0.2 10.1 11 0 0 11 11 11 6 WD domain, G-beta repeat HELP PF03451.9 KFM07790.1 - 5e-12 45.1 0.0 1e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 HELP motif Ribosomal_S7 PF00177.16 KFM07790.1 - 0.0062 16.1 0.6 0.012 15.2 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e SlyX PF04102.7 KFM07790.1 - 0.079 13.3 0.4 0.079 13.3 0.3 1.9 2 0 0 2 2 2 0 SlyX CPSF_A PF03178.10 KFM07790.1 - 0.085 11.9 0.0 3.4 6.6 0.0 2.9 2 1 1 3 3 3 0 CPSF A subunit region Ndc1_Nup PF09531.5 KFM07790.1 - 0.89 7.8 6.8 1.6 7.0 4.7 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup COX7a PF02238.10 KFM07791.1 - 5e-26 90.1 0.0 6.4e-26 89.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIa Ion_trans PF00520.26 KFM07792.1 - 0.009 15.2 0.5 0.0099 15.1 0.3 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.7 KFM07792.1 - 0.052 11.9 0.2 0.05 12.0 0.1 1.0 1 0 0 1 1 1 0 Polycystin cation channel DUF1353 PF07087.6 KFM07792.1 - 0.099 12.1 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) 3-HAO PF06052.7 KFM07794.1 - 5.9e-77 256.2 0.1 1.2e-74 248.7 0.3 2.1 2 0 0 2 2 2 2 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 KFM07794.1 - 2.8e-13 49.1 0.0 1.3e-05 24.5 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 KFM07794.1 - 7e-06 25.3 0.1 0.0024 17.2 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 KFM07794.1 - 0.0008 19.0 0.0 1.5 8.4 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_1 PF00190.17 KFM07794.1 - 0.012 15.0 0.0 0.51 9.7 0.0 2.2 2 0 0 2 2 2 0 Cupin Cupin_6 PF12852.2 KFM07794.1 - 0.027 14.0 0.0 0.91 9.1 0.0 2.1 2 0 0 2 2 2 0 Cupin AraC_binding_2 PF14525.1 KFM07794.1 - 0.042 13.4 0.0 0.096 12.2 0.0 1.5 2 0 0 2 2 2 0 AraC-binding-like domain WD40 PF00400.27 KFM07795.1 - 0.00036 20.3 0.1 0.0099 15.7 0.0 3.0 3 0 0 3 3 3 1 WD domain, G-beta repeat Lgl_C PF08596.5 KFM07795.1 - 0.03 12.7 0.0 0.075 11.4 0.0 1.6 1 0 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal DUF3087 PF11286.3 KFM07795.1 - 0.18 11.0 0.1 6.1 6.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) tRNA_int_end_N2 PF12928.2 KFM07796.1 - 4.9e-20 70.7 1.5 5.1e-20 70.7 0.0 1.9 2 0 0 2 2 2 1 tRNA-splicing endonuclease subunit sen54 N-term SH3_1 PF00018.23 KFM07798.1 - 7.8e-36 121.2 0.4 1.2e-16 59.7 0.0 2.5 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.1 KFM07798.1 - 4.5e-34 115.7 0.4 9.2e-16 57.1 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 KFM07798.1 - 1.9e-28 97.7 0.0 6.4e-16 57.5 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH2 PF00017.19 KFM07798.1 - 1e-24 86.0 0.0 1.7e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 SH2 domain SH3_3 PF08239.6 KFM07798.1 - 0.0026 17.8 0.1 0.013 15.6 0.0 2.0 2 0 0 2 2 2 1 Bacterial SH3 domain SH3_4 PF06347.8 KFM07798.1 - 0.038 13.5 0.0 0.066 12.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain Mito_carr PF00153.22 KFM07799.1 - 4.1e-69 228.3 2.5 2.2e-23 81.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S7 PF00177.16 KFM07800.1 - 1.1e-42 145.0 1.3 1.5e-42 144.6 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e VHS PF00790.14 KFM07801.1 - 8e-46 155.1 1.8 3.5e-45 153.0 0.0 2.4 2 1 0 2 2 2 1 VHS domain GAT PF03127.9 KFM07801.1 - 2.3e-30 104.5 3.2 2.3e-30 104.5 2.2 2.3 2 0 0 2 2 2 1 GAT domain Alpha_adaptinC2 PF02883.15 KFM07801.1 - 2.1e-28 98.9 0.0 2.1e-28 98.9 0.0 2.0 3 0 0 3 3 3 1 Adaptin C-terminal domain KAT11 PF08214.6 KFM07801.1 - 0.0013 17.9 0.5 0.002 17.3 0.4 1.2 1 0 0 1 1 1 1 Histone acetylation protein UCH PF00443.24 KFM07801.1 - 0.024 13.7 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Usg PF06233.7 KFM07801.1 - 0.084 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Usg-like family Nucleopor_Nup85 PF07575.8 KFM07802.1 - 3.3e-207 689.1 13.0 3.8e-207 689.0 9.0 1.0 1 0 0 1 1 1 1 Nup85 Nucleoporin Rad60-SLD PF11976.3 KFM07803.1 - 1e-26 92.3 0.1 1.3e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KFM07803.1 - 1.2e-12 47.0 0.1 1.5e-12 46.7 0.1 1.3 1 1 0 1 1 1 1 Ubiquitin family NT5C PF06941.7 KFM07805.1 - 5.1e-54 182.6 0.1 5.6e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Arm PF00514.18 KFM07806.1 - 1.8e-10 40.2 0.0 1.6e-05 24.5 0.0 2.9 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFM07806.1 - 0.00055 20.1 0.0 0.0066 16.7 0.0 2.1 1 1 0 1 1 1 1 HEAT repeats Arm_2 PF04826.8 KFM07806.1 - 0.0083 15.2 0.1 1.9 7.5 0.0 2.0 1 1 1 2 2 2 2 Armadillo-like RICTOR_N PF14664.1 KFM07806.1 - 0.0086 14.7 0.4 0.014 13.9 0.3 1.4 1 1 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term Adaptin_N PF01602.15 KFM07806.1 - 0.018 13.4 0.6 0.03 12.6 0.4 1.5 1 1 0 1 1 1 0 Adaptin N terminal region GRIP PF01465.15 KFM07806.1 - 0.028 13.9 0.6 0.3 10.6 0.0 2.6 2 0 0 2 2 2 0 GRIP domain Glycoprotein PF03409.10 KFM07806.1 - 0.048 12.3 0.1 0.064 11.9 0.1 1.1 1 0 0 1 1 1 0 Transmembrane glycoprotein V-ATPase_H_N PF03224.9 KFM07806.1 - 0.063 12.3 0.2 0.072 12.2 0.1 1.2 1 0 0 1 1 1 0 V-ATPase subunit H WAPL PF07814.8 KFM07806.1 - 0.07 11.8 0.2 0.098 11.3 0.1 1.4 1 0 0 1 1 1 0 Wings apart-like protein regulation of heterochromatin ParcG PF10274.4 KFM07806.1 - 0.1 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Parkin co-regulated protein HEAT PF02985.17 KFM07806.1 - 0.12 12.5 0.2 5.6 7.3 0.0 2.8 3 0 0 3 3 3 0 HEAT repeat BTB_2 PF02214.17 KFM07807.1 - 2e-11 43.9 0.0 3.6e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KFM07807.1 - 0.0054 16.7 0.0 0.0081 16.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain PadR PF03551.9 KFM07807.1 - 0.11 12.2 0.2 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Mt_ATP-synt_D PF05873.7 KFM07808.1 - 9.2e-58 194.4 4.2 1e-57 194.2 2.9 1.0 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) IncA PF04156.9 KFM07808.1 - 0.026 14.1 1.1 0.043 13.3 0.8 1.4 1 0 0 1 1 1 0 IncA protein DUF848 PF05852.6 KFM07808.1 - 0.039 13.7 1.1 0.059 13.2 0.8 1.3 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Bac_GDH PF05088.7 KFM07808.1 - 0.084 10.2 1.3 0.1 9.9 0.9 1.0 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase Val_tRNA-synt_C PF10458.4 KFM07808.1 - 0.095 12.7 0.9 0.29 11.2 0.3 2.1 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm DUF2937 PF11157.3 KFM07808.1 - 0.2 10.9 4.5 0.64 9.3 1.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) RF-1 PF00472.15 KFM07809.1 - 1.2e-15 57.2 2.9 1.7e-15 56.8 2.0 1.3 1 0 0 1 1 1 1 RF-1 domain DUF2603 PF10788.4 KFM07809.1 - 0.029 14.1 0.6 0.036 13.8 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2603) PET PF06297.9 KFM07809.1 - 0.074 12.7 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 PET Domain IncA PF04156.9 KFM07810.1 - 2.2 7.8 60.5 0.18 11.4 9.3 4.0 3 1 1 4 4 4 0 IncA protein BLOC1_2 PF10046.4 KFM07810.1 - 2.3 8.3 34.3 0.024 14.7 8.4 4.8 4 2 1 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Reo_sigmaC PF04582.7 KFM07810.1 - 2.5 7.2 8.0 1.4 8.0 1.6 2.3 2 0 0 2 2 2 0 Reovirus sigma C capsid protein M_domain PF12938.2 KFM07810.1 - 2.9 7.6 17.9 1 9.0 0.1 2.9 1 1 2 3 3 3 0 M domain of GW182 DUF1664 PF07889.7 KFM07810.1 - 3 7.6 26.4 7.9 6.2 0.5 4.3 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) DUF2573 PF10835.3 KFM07810.1 - 4 7.5 10.9 5.1 7.2 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2573) CCDC155 PF14662.1 KFM07810.1 - 6.6 6.2 55.8 0.37 10.3 10.0 3.3 4 1 0 4 4 4 0 Coiled-coil region of CCDC155 DUF3540 PF12059.3 KFM07810.1 - 7.7 6.0 12.6 8.1 6.0 2.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3540) Hid1 PF12722.2 KFM07811.1 - 3.9e-247 822.3 0.0 4.9e-246 818.6 0.0 1.9 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 KFM07811.1 - 2.2e-228 759.7 0.0 2.6e-228 759.5 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Otopetrin PF03189.8 KFM07812.1 - 2.3e-40 138.9 29.9 8e-20 71.2 2.9 4.0 3 1 1 4 4 4 3 Otopetrin SdpI PF13630.1 KFM07812.1 - 0.002 17.7 1.9 0.002 17.7 1.3 4.0 3 0 0 3 3 3 2 SdpI/YhfL protein family Rtt106 PF08512.7 KFM07812.1 - 0.081 12.9 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 Histone chaperone Rttp106-like Adipogenin PF15202.1 KFM07812.1 - 0.26 11.1 2.4 0.56 10.1 0.1 2.8 3 0 0 3 3 3 0 Adipogenin Ank_2 PF12796.2 KFM07813.1 - 1.2e-23 83.2 0.1 8.7e-19 67.6 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFM07813.1 - 2.9e-23 81.8 2.0 1.6e-12 47.6 0.2 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 KFM07813.1 - 5.9e-22 76.3 2.8 8.4e-10 37.9 0.2 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 KFM07813.1 - 3.9e-16 57.5 1.6 1.2e-05 25.0 0.1 4.7 4 1 1 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 KFM07813.1 - 7.1e-16 57.8 2.4 1.5e-08 34.6 0.3 3.8 1 1 3 4 4 4 3 Ankyrin repeats (many copies) SAM_1 PF00536.25 KFM07813.1 - 1.4e-10 41.1 0.1 6e-10 39.1 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFM07813.1 - 1.7e-05 24.5 0.0 3.1e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Paramyxo_C PF01692.13 KFM07813.1 - 0.079 12.5 5.4 0.16 11.5 3.7 1.4 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c FA_desaturase PF00487.19 KFM07814.1 - 7.2e-27 94.4 14.8 9.3e-27 94.0 10.2 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Aa_trans PF01490.13 KFM07816.1 - 1.4e-19 69.8 33.3 2.9e-11 42.5 15.2 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KFM07816.1 - 8.1e-08 31.4 21.3 0.00057 18.8 1.0 2.5 2 1 0 2 2 2 2 Tryptophan/tyrosine permease family Acetyltransf_3 PF13302.1 KFM07817.1 - 5.4e-21 75.2 0.9 4e-20 72.4 0.6 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFM07817.1 - 1.1e-05 25.3 0.0 1.8e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KFM07817.1 - 2.4e-05 23.9 0.0 4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 KFM07817.1 - 0.0026 17.7 0.1 0.0058 16.5 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain EBP50_C-term PF09007.6 KFM07818.1 - 1.3e-22 79.3 0.3 2e-22 78.7 0.2 1.3 1 0 0 1 1 1 1 EBP50, C-terminal PDZ PF00595.19 KFM07818.1 - 1.7e-14 53.7 0.0 2.7e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM07818.1 - 5.7e-05 22.9 0.0 9.1e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.9 KFM07818.1 - 0.051 13.5 0.0 0.076 13.0 0.0 1.2 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain Ras PF00071.17 KFM07819.1 - 6.6e-59 197.9 0.1 7.3e-59 197.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM07819.1 - 2.1e-18 66.9 0.0 2.6e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM07819.1 - 1.8e-14 53.3 0.1 2e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFM07819.1 - 1.3e-07 30.9 0.0 1.6e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFM07819.1 - 0.0019 17.6 0.0 0.003 17.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFM07819.1 - 0.0033 17.3 0.0 0.0051 16.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.13 KFM07819.1 - 0.017 14.1 0.3 0.038 13.0 0.1 1.7 2 1 0 2 2 2 0 Septin DUF1792 PF08759.6 KFM07819.1 - 0.032 13.8 0.1 0.052 13.1 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1792) AAA_24 PF13479.1 KFM07819.1 - 0.046 13.2 0.1 0.092 12.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.13 KFM07819.1 - 0.054 12.7 0.1 0.3 10.3 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.1 KFM07819.1 - 0.11 12.6 0.0 0.6 10.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain Xylo_C PF12529.3 KFM07820.1 - 4.5e-71 237.8 0.0 7.2e-71 237.2 0.0 1.3 1 0 0 1 1 1 1 Xylosyltransferase C terminal Branch PF02485.16 KFM07820.1 - 8.7e-54 182.2 2.0 1.2e-53 181.7 1.4 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Ribosomal_L27 PF01016.14 KFM07822.1 - 3.9e-29 100.2 0.1 4.9e-29 99.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein ERCC4 PF02732.10 KFM07823.1 - 6.3e-08 32.4 0.6 1.1e-07 31.7 0.1 1.7 2 0 0 2 2 2 1 ERCC4 domain Mito_fiss_reg PF05308.6 KFM07823.1 - 0.053 12.8 3.6 0.098 12.0 2.5 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Auts2 PF15336.1 KFM07823.1 - 0.055 13.5 4.9 0.094 12.7 3.4 1.3 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein OS-D PF03392.8 KFM07823.1 - 0.52 10.3 0.0 0.52 10.3 0.0 2.8 3 2 0 3 3 3 0 Insect pheromone-binding family, A10/OS-D LRR_8 PF13855.1 KFM07824.1 - 1.6e-13 50.2 16.0 3.2e-09 36.4 4.7 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 KFM07824.1 - 5.4e-13 48.2 10.6 2.2e-07 30.3 1.6 2.7 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM07824.1 - 7.9e-12 43.4 13.8 0.017 15.0 0.3 4.8 5 0 0 5 5 4 3 Leucine Rich Repeat LRR_7 PF13504.1 KFM07824.1 - 5e-07 28.8 17.5 0.29 11.5 0.9 5.4 5 0 0 5 5 5 3 Leucine rich repeat Pex14_N PF04695.8 KFM07824.1 - 0.0041 17.1 1.4 0.011 15.8 1.0 1.7 1 1 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF572 PF04502.8 KFM07824.1 - 0.0062 15.7 20.3 0.0088 15.3 14.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) LRR_6 PF13516.1 KFM07824.1 - 0.023 14.7 14.5 2.4 8.5 0.0 5.0 4 1 1 5 5 5 0 Leucine Rich repeat LMBR1 PF04791.11 KFM07824.1 - 0.033 12.7 2.8 0.041 12.4 2.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein SAPS PF04499.10 KFM07824.1 - 0.082 11.5 5.7 0.1 11.2 3.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein GAGA_bind PF06217.7 KFM07824.1 - 0.086 12.7 10.4 0.12 12.3 7.2 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family MIP-T3 PF10243.4 KFM07824.1 - 0.36 9.2 30.4 0.5 8.7 21.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Ycf1 PF05758.7 KFM07824.1 - 0.37 8.4 10.7 0.43 8.2 7.4 1.1 1 0 0 1 1 1 0 Ycf1 DUF2413 PF10310.4 KFM07824.1 - 2.2 7.0 16.7 2.8 6.6 11.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DDHD PF02862.12 KFM07824.1 - 2.5 7.8 10.1 3.8 7.2 7.0 1.3 1 0 0 1 1 1 0 DDHD domain DUF1510 PF07423.6 KFM07824.1 - 4.1 6.7 17.7 5.6 6.2 12.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) V_ATPase_I PF01496.14 KFM07824.1 - 4.9 4.8 9.8 6.1 4.5 6.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Neur_chan_memb PF02932.11 KFM07824.1 - 5.1 6.9 8.2 8.6 6.1 5.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1675 PF07897.6 KFM07824.1 - 6 6.6 15.4 8.4 6.1 10.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Borrelia_P83 PF05262.6 KFM07824.1 - 6.6 4.8 22.5 8.2 4.5 15.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein AMP-binding PF00501.23 KFM07825.1 - 4e-96 321.9 0.0 4.7e-96 321.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFM07825.1 - 7.1e-15 55.7 0.0 1.9e-14 54.3 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LRR_8 PF13855.1 KFM07826.1 - 2.7e-55 183.9 28.8 4.1e-16 58.4 0.1 5.5 1 1 5 6 6 6 6 Leucine rich repeat LRR_4 PF12799.2 KFM07826.1 - 1.1e-21 75.9 28.4 3.9e-06 26.3 0.1 6.7 1 1 6 8 8 8 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM07826.1 - 3.9e-19 65.7 20.4 0.011 15.5 0.0 11.3 12 1 0 12 12 12 5 Leucine Rich Repeat LRR_5 PF13306.1 KFM07826.1 - 4.1e-15 55.6 0.0 4.1e-06 26.5 0.0 2.7 1 1 2 3 3 3 3 Leucine rich repeats (6 copies) LRRNT PF01462.13 KFM07826.1 - 1.2e-07 30.9 4.3 1.2e-07 30.9 3.0 2.4 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.1 KFM07826.1 - 4e-06 26.3 18.4 8.9 6.7 0.0 9.5 11 0 0 11 11 11 2 Leucine Rich repeat LRR_7 PF13504.1 KFM07826.1 - 6.5e-06 25.5 21.0 25 5.6 0.0 10.0 10 0 0 10 10 10 0 Leucine rich repeat LRR_9 PF14580.1 KFM07826.1 - 0.0003 20.3 2.8 0.065 12.7 0.0 3.3 1 1 2 3 3 3 1 Leucine-rich repeat Thioredox_DsbH PF03190.10 KFM07828.1 - 8.3e-76 253.2 0.0 1.4e-75 252.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 KFM07828.1 - 6.4e-12 45.3 0.0 1.4e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KFM07828.1 - 0.00044 20.4 0.1 0.00094 19.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain Glyco_hydro_88 PF07470.8 KFM07828.1 - 0.076 12.0 0.1 1.1 8.2 0.0 2.4 2 0 0 2 2 2 0 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.8 KFM07828.1 - 0.13 11.5 0.7 0.4 9.9 0.0 2.1 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus Ion_trans PF00520.26 KFM07829.1 - 1.2e-207 684.0 83.5 7.8e-63 211.3 10.3 4.2 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.7 KFM07829.1 - 7.3e-13 47.7 79.7 8.6e-09 34.3 1.6 9.4 6 3 3 9 9 9 5 Polycystin cation channel EphA2_TM PF14575.1 KFM07829.1 - 0.0022 18.3 0.9 46 4.5 0.0 4.6 3 0 0 3 3 3 2 Ephrin type-A receptor 2 transmembrane domain ABC_membrane PF00664.18 KFM07830.1 - 1.9e-82 276.7 32.5 1.8e-41 142.3 10.1 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFM07830.1 - 4.2e-54 182.5 0.2 4.9e-29 101.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KFM07830.1 - 5.4e-10 38.8 0.0 0.00036 19.8 0.0 4.0 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 KFM07830.1 - 5.2e-05 23.1 0.3 0.072 13.0 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 KFM07830.1 - 8.5e-05 22.6 1.5 0.011 15.7 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 KFM07830.1 - 0.00016 20.9 1.3 0.016 14.4 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 KFM07830.1 - 0.00091 18.6 2.6 0.084 12.2 0.1 2.9 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.1 KFM07830.1 - 0.0016 18.4 0.1 44 3.9 0.0 4.5 3 1 0 4 4 4 0 AAA domain Miro PF08477.8 KFM07830.1 - 0.0022 18.5 4.8 0.036 14.5 0.0 2.8 3 0 0 3 3 2 1 Miro-like protein AAA_29 PF13555.1 KFM07830.1 - 0.0029 17.1 1.0 1 8.9 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Dynamin_N PF00350.18 KFM07830.1 - 0.0048 16.7 1.1 0.11 12.3 0.0 3.0 3 0 0 3 3 3 1 Dynamin family AAA_23 PF13476.1 KFM07830.1 - 0.0075 16.6 1.3 2.7 8.2 0.0 3.4 4 0 0 4 4 3 1 AAA domain GTP_EFTU PF00009.22 KFM07830.1 - 0.013 14.9 0.1 0.26 10.7 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF815 PF05673.8 KFM07830.1 - 0.081 11.8 1.2 0.85 8.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_17 PF13207.1 KFM07830.1 - 0.082 13.7 2.8 5.3 7.8 0.0 3.3 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.17 KFM07830.1 - 0.15 12.2 0.1 9.1 6.5 0.0 3.0 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.7 KFM07830.1 - 0.17 10.9 0.5 3.4 6.7 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.1 KFM07830.1 - 0.18 11.9 1.7 15 5.7 0.0 3.3 2 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 KFM07830.1 - 0.26 10.3 0.2 2.3 7.3 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ABC_ATPase PF09818.4 KFM07830.1 - 0.29 9.6 0.5 3.4 6.1 0.1 2.6 3 0 0 3 3 3 0 Predicted ATPase of the ABC class MobB PF03205.9 KFM07830.1 - 0.46 10.1 2.3 3.2 7.4 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 KFM07830.1 - 0.93 9.2 7.1 3.1 7.5 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function DUF87 LUC7 PF03194.10 KFM07832.1 - 2.7e-68 230.2 31.9 2.7e-68 230.2 22.1 3.5 1 1 2 3 3 3 1 LUC7 N_terminus MIP-T3 PF10243.4 KFM07832.1 - 0.79 8.1 83.1 1.8 6.9 57.6 1.6 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Kunitz_BPTI PF00014.18 KFM07834.1 - 6.3e-34 115.9 31.9 2.8e-21 75.4 4.9 3.4 3 0 0 3 3 3 2 Kunitz/Bovine pancreatic trypsin inhibitor domain I-set PF07679.11 KFM07834.1 - 3.4e-17 62.0 0.0 6.5e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain NTR PF01759.16 KFM07834.1 - 3e-11 42.8 0.0 7.4e-11 41.5 0.0 1.7 1 0 0 1 1 1 1 UNC-6/NTR/C345C module Ig_2 PF13895.1 KFM07834.1 - 3.9e-10 39.7 0.0 1.3e-09 38.0 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFM07834.1 - 8.2e-08 32.1 0.0 2.3e-07 30.6 0.0 1.7 2 0 0 2 2 2 1 Immunoglobulin V-set domain WAP PF00095.16 KFM07834.1 - 5.1e-07 29.5 11.2 5.1e-07 29.5 7.7 4.3 4 1 0 4 4 4 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Ig_3 PF13927.1 KFM07834.1 - 1.1e-06 29.0 0.1 3e-06 27.6 0.1 1.8 1 0 0 1 1 1 1 Immunoglobulin domain Kazal_2 PF07648.10 KFM07834.1 - 4.1e-06 26.6 2.9 4.1e-06 26.6 2.0 2.8 3 0 0 3 3 3 1 Kazal-type serine protease inhibitor domain ig PF00047.20 KFM07834.1 - 6.5e-05 22.9 0.2 0.00032 20.7 0.1 2.2 1 1 0 1 1 1 1 Immunoglobulin domain Porphobil_deam PF01379.15 KFM07834.1 - 0.05 12.5 0.0 0.093 11.6 0.0 1.4 1 0 0 1 1 1 0 Porphobilinogen deaminase, dipyromethane cofactor binding domain BTG PF07742.7 KFM07835.1 - 3.8e-42 142.5 0.0 6.2e-42 141.8 0.0 1.3 1 0 0 1 1 1 1 BTG family PAM2 PF07145.10 KFM07835.1 - 7.8e-07 28.1 3.3 0.0025 17.2 0.2 2.9 2 0 0 2 2 2 2 Ataxin-2 C-terminal region NDK PF00334.14 KFM07837.1 - 7.1e-55 184.4 0.0 8e-55 184.3 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.13 KFM07837.1 - 0.14 11.9 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ NDK PF00334.14 KFM07838.1 - 1.2e-56 190.2 0.0 1.4e-56 190.0 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.13 KFM07838.1 - 0.086 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ MBT PF02820.13 KFM07839.1 - 7.9e-89 291.6 2.4 2.6e-30 104.1 0.1 4.5 4 0 0 4 4 4 4 mbt repeat WD40 PF00400.27 KFM07840.1 - 9.5e-12 44.3 0.1 0.47 10.4 0.0 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KFM07840.1 - 0.003 17.0 0.0 2.4 7.7 0.0 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Carb_anhydrase PF00194.16 KFM07841.1 - 8.3e-62 208.4 0.0 9.5e-62 208.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF1647 PF07801.6 KFM07841.1 - 0.11 12.0 0.2 0.33 10.4 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) Laminin_G_2 PF02210.19 KFM07842.1 - 2.1e-18 66.5 0.2 2.7e-18 66.2 0.2 1.1 1 0 0 1 1 1 1 Laminin G domain EGF PF00008.22 KFM07842.1 - 1.7e-17 63.0 40.1 2.7e-05 24.0 7.1 4.8 4 1 0 4 4 4 4 EGF-like domain Laminin_G_1 PF00054.18 KFM07842.1 - 2.6e-16 59.8 0.1 3.3e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Laminin G domain EGF_2 PF07974.8 KFM07842.1 - 4e-06 26.8 46.1 0.0049 16.9 5.6 4.7 4 1 0 4 4 4 4 EGF-like domain hEGF PF12661.2 KFM07842.1 - 0.34 11.0 31.9 0.38 10.9 2.0 6.2 4 1 0 4 4 4 0 Human growth factor-like EGF FXa_inhibition PF14670.1 KFM07842.1 - 1.1 9.4 40.1 0.15 12.2 4.4 4.6 4 0 0 4 4 4 0 Coagulation Factor Xa inhibitory site Laminin_G_2 PF02210.19 KFM07843.1 - 1e-37 129.0 0.6 2.8e-18 66.1 0.0 2.1 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.18 KFM07843.1 - 4.9e-33 113.9 0.1 6e-17 61.8 0.0 2.1 2 0 0 2 2 2 2 Laminin G domain EGF PF00008.22 KFM07843.1 - 3.1e-09 36.6 17.2 0.00017 21.4 4.9 2.8 2 0 0 2 2 2 2 EGF-like domain Laminin_G_3 PF13385.1 KFM07843.1 - 2.5e-05 24.5 0.3 0.0078 16.4 0.0 2.3 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily FXa_inhibition PF14670.1 KFM07843.1 - 0.0006 19.8 20.8 0.0057 16.7 4.1 2.8 2 1 0 2 2 2 2 Coagulation Factor Xa inhibitory site hEGF PF12661.2 KFM07843.1 - 0.00063 19.6 9.1 0.13 12.3 0.6 3.1 2 0 0 2 2 2 2 Human growth factor-like EGF EGF_2 PF07974.8 KFM07843.1 - 0.03 14.5 29.0 0.71 10.0 9.7 3.2 2 1 1 3 3 3 0 EGF-like domain EGF_3 PF12947.2 KFM07843.1 - 0.65 10.0 16.9 0.73 9.8 2.7 2.9 2 0 0 2 2 2 0 EGF domain TFIIS_M PF07500.9 KFM07844.1 - 2e-34 118.0 4.2 1.2e-33 115.5 2.9 2.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 KFM07844.1 - 1.3e-22 80.4 0.0 5.4e-22 78.5 0.0 2.2 2 0 0 2 2 2 1 SPOC domain PHD PF00628.24 KFM07844.1 - 8.7e-10 38.1 10.6 2.6e-09 36.6 7.3 1.9 1 0 0 1 1 1 1 PHD-finger Y_phosphatase PF00102.22 KFM07845.1 - 3.4e-13 49.4 0.0 1.1e-08 34.7 0.0 2.1 1 1 1 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.15 KFM07845.1 - 3.1e-09 36.5 0.0 4.3e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFM07845.1 - 0.036 14.3 0.2 0.37 11.0 0.1 2.0 1 1 1 2 2 2 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KFM07845.1 - 0.11 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Gln-synt_C PF00120.19 KFM07846.1 - 1.9e-48 164.8 0.0 3.1e-48 164.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 KFM07846.1 - 9e-06 25.1 0.3 4.3e-05 22.9 0.2 2.2 1 1 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain KH_3 PF13014.1 KFM07847.1 - 1.9e-05 24.2 0.0 5.4e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 KH domain KH_1 PF00013.24 KFM07847.1 - 2.1e-05 24.0 0.0 3.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 KH domain DNA_primase_lrg PF04104.9 KFM07849.1 - 6.9e-89 297.5 0.1 1.4e-88 296.5 0.0 1.6 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase, large subunit Ras PF00071.17 KFM07850.1 - 9.2e-53 177.9 1.0 1.5e-52 177.2 0.7 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM07850.1 - 3.8e-19 69.3 0.1 6.5e-19 68.5 0.1 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM07850.1 - 5.9e-10 38.6 0.6 8.1e-10 38.2 0.4 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFM07850.1 - 1.1e-06 28.6 0.0 2.4e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFM07850.1 - 1.5e-05 24.5 0.2 5.8e-05 22.5 0.2 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFM07850.1 - 9.3e-05 21.6 0.1 0.00013 21.2 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 KFM07850.1 - 0.0029 17.1 3.6 0.0074 15.8 0.4 2.4 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein G-alpha PF00503.15 KFM07850.1 - 0.0066 15.1 0.9 0.055 12.1 0.1 2.3 2 1 1 3 3 3 1 G-protein alpha subunit FeoB_N PF02421.13 KFM07850.1 - 0.011 14.9 0.2 1.3 8.3 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B YwhD PF08741.5 KFM07850.1 - 0.075 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 YwhD family BAG PF02179.11 KFM07851.1 - 2.2e-08 34.0 0.2 6.2e-08 32.6 0.2 1.7 1 0 0 1 1 1 1 BAG domain Big_3_3 PF13750.1 KFM07851.1 - 0.039 13.3 0.1 0.062 12.7 0.1 1.3 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) DUF4611 PF15387.1 KFM07851.1 - 0.28 11.3 4.5 0.85 9.8 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4611) DUF4168 PF13767.1 KFM07851.1 - 1.4 9.5 7.4 0.37 11.4 2.7 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4168) Enkurin PF13864.1 KFM07851.1 - 2.5 8.3 10.4 8.7 6.6 0.2 2.5 2 1 0 2 2 2 0 Calmodulin-binding DUF2951 PF11166.3 KFM07852.1 - 4.5 7.1 7.5 1 9.2 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) BEN PF10523.4 KFM07853.1 - 5.3e-08 32.7 0.0 1.3e-07 31.5 0.0 1.7 2 0 0 2 2 2 1 BEN domain bZIP_2 PF07716.10 KFM07853.1 - 0.75 9.6 3.1 0.33 10.8 0.3 1.9 2 0 0 2 2 2 0 Basic region leucine zipper Spectrin PF00435.16 KFM07854.1 - 3.7e-219 711.7 479.6 8.9e-17 61.3 4.8 42.7 39 2 5 44 44 44 33 Spectrin repeat GAS2 PF02187.12 KFM07854.1 - 5.3e-34 115.8 0.9 1.7e-33 114.1 0.6 2.0 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.26 KFM07854.1 - 2.1e-30 104.9 12.3 5.4e-16 58.5 0.0 8.2 8 0 0 8 8 8 2 Calponin homology (CH) domain EF-hand_1 PF00036.27 KFM07854.1 - 2.3e-12 45.2 2.3 5.4e-05 22.1 0.0 3.1 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 KFM07854.1 - 5.3e-10 39.2 2.8 1.6e-09 37.7 0.4 3.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KFM07854.1 - 6.4e-10 38.0 2.4 0.00066 19.3 0.4 3.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 KFM07854.1 - 1.2e-09 37.6 0.3 3.3e-07 29.7 0.1 3.8 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 KFM07854.1 - 1.1e-08 33.9 4.1 3.9e-05 22.7 1.0 3.1 2 0 0 2 2 2 2 EF hand CAMSAP_CH PF11971.3 KFM07854.1 - 8.8e-08 31.7 0.1 3.8e-05 23.2 0.0 4.3 3 0 0 3 3 3 1 CAMSAP CH domain Laminin_II PF06009.7 KFM07854.1 - 0.015 15.0 0.2 0.015 15.0 0.1 30.7 24 8 5 32 32 32 0 Laminin Domain II TGFb_propeptide PF00688.13 KFM07855.1 - 5e-58 196.2 0.4 1.9e-57 194.3 0.3 1.9 1 1 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.15 KFM07855.1 - 4.6e-44 149.0 1.0 1e-43 147.8 0.7 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain YkuD_2 PF13645.1 KFM07855.1 - 0.078 12.1 0.4 0.16 11.1 0.3 1.4 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain HMGL-like PF00682.14 KFM07856.1 - 3.1e-67 226.6 0.0 3.7e-67 226.4 0.0 1.0 1 0 0 1 1 1 1 HMGL-like GDNF PF02351.11 KFM07859.1 - 2.1e-22 79.3 50.0 5.8e-11 42.7 8.8 3.9 3 1 0 3 3 3 3 GDNF/GAS1 domain DUF1874 PF08960.5 KFM07859.1 - 0.13 11.9 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1874) 7tm_1 PF00001.16 KFM07860.1 - 2.2e-59 200.6 22.7 2.9e-59 200.3 15.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Orexin_rec2 PF03827.8 KFM07860.1 - 1.9e-25 88.6 0.4 1.9e-25 88.6 0.3 2.3 3 0 0 3 3 3 1 Orexin receptor type 2 7TM_GPCR_Srsx PF10320.4 KFM07860.1 - 0.00012 21.3 22.3 0.00043 19.5 15.5 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF2231 PF09990.4 KFM07860.1 - 2.4 8.5 8.7 0.47 10.8 2.8 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) DUF1669 PF07894.7 KFM07861.1 - 3.5e-107 357.8 0.0 1.2e-106 356.1 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1669) PLDc_2 PF13091.1 KFM07861.1 - 4e-08 33.0 0.1 8.4e-08 32.0 0.1 1.6 1 0 0 1 1 1 1 PLD-like domain Regulator_TrmB PF11495.3 KFM07861.1 - 0.01 14.8 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB DUF1908 PF08926.6 KFM07862.1 - 9.1e-154 510.1 0.3 9.1e-154 510.1 0.2 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF1908) Pkinase PF00069.20 KFM07862.1 - 2.1e-60 204.0 0.0 6e-60 202.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM07862.1 - 2.7e-23 82.3 0.0 6.2e-23 81.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase PDZ PF00595.19 KFM07862.1 - 3.5e-08 33.5 0.0 7.4e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM07862.1 - 3.8e-06 26.7 0.0 8e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Kinase-like PF14531.1 KFM07862.1 - 5e-05 22.3 0.1 0.00095 18.2 0.0 2.4 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 KFM07862.1 - 0.0067 16.1 0.1 0.069 12.8 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Tricorn_PDZ PF14685.1 KFM07862.1 - 0.02 14.6 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 Tricorn protease PDZ domain Seadorna_VP7 PF07387.6 KFM07862.1 - 0.21 10.3 0.2 0.37 9.5 0.2 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 SH2 PF00017.19 KFM07863.1 - 1.5e-40 136.8 0.1 1.9e-19 69.2 0.0 2.7 2 0 0 2 2 2 2 SH2 domain RhoGAP PF00620.22 KFM07863.1 - 3.2e-26 91.7 0.8 2.3e-25 88.9 0.0 2.5 2 1 1 3 3 3 1 RhoGAP domain SH3_1 PF00018.23 KFM07863.1 - 5.3e-05 22.5 0.3 0.0067 15.7 0.0 3.3 3 0 0 3 3 3 1 SH3 domain SH3_9 PF14604.1 KFM07863.1 - 0.00077 18.9 0.3 0.0033 16.9 0.2 2.2 2 1 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KFM07863.1 - 0.0038 16.6 0.3 0.014 14.8 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain ATG11 PF10377.4 KFM07863.1 - 0.0057 16.5 0.6 0.0057 16.5 0.4 1.8 2 0 0 2 2 2 1 Autophagy-related protein 11 CENP-Q PF13094.1 KFM07863.1 - 0.11 12.5 15.5 0.18 11.8 10.2 1.8 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Ras PF00071.17 KFM07864.1 - 1e-15 57.4 0.1 1.1e-15 57.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM07864.1 - 7.8e-06 26.3 0.0 8.4e-06 26.2 0.0 1.0 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM07864.1 - 0.0026 17.0 0.0 0.0029 16.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KFM07864.1 - 0.0075 15.5 0.0 0.0078 15.4 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 KFM07864.1 - 0.13 12.1 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain LSM PF01423.17 KFM07865.1 - 3.9e-14 51.9 0.0 5.5e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KFM07865.1 - 0.094 12.6 0.0 0.12 12.2 0.0 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain Peptidase_C15 PF01470.12 KFM07866.1 - 6.4e-18 65.3 0.0 7.9e-18 65.0 0.0 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase DUF3060 PF11259.3 KFM07866.1 - 0.011 15.3 0.4 2.6 7.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3060) NAD_binding_5 PF07994.7 KFM07867.1 - 1.2e-92 310.6 0.0 1.4e-92 310.3 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 KFM07867.1 - 6.4e-48 161.2 0.1 9.7e-48 160.6 0.1 1.3 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase ELL PF10390.4 KFM07868.1 - 6.8e-97 324.1 0.0 6.8e-97 324.1 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase II elongation factor ELL Occludin_ELL PF07303.8 KFM07868.1 - 5.6e-37 126.5 12.4 5.6e-37 126.5 8.6 2.9 3 0 0 3 3 3 1 Occludin homology domain Pox_Ag35 PF03286.9 KFM07868.1 - 0.03 13.8 8.3 0.065 12.7 5.8 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FAM176 PF14851.1 KFM07868.1 - 0.3 10.7 7.3 0.69 9.5 5.0 1.5 1 0 0 1 1 1 0 FAM176 family RP-C_C PF11800.3 KFM07868.1 - 1.2 8.8 9.6 1.1 8.8 0.5 2.4 2 0 0 2 2 2 0 Replication protein C C-terminal region Seryl_tRNA_N PF02403.17 KFM07868.1 - 1.9 8.5 14.0 0.27 11.2 1.3 2.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TraV PF09676.5 KFM07868.1 - 9.9 6.8 12.4 8.4 7.1 5.1 2.8 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) Uds1 PF15456.1 KFM07868.1 - 10 6.1 17.2 1.5 8.7 3.2 2.8 3 0 0 3 3 3 0 Up-regulated During Septation TPR_11 PF13414.1 KFM07869.1 - 1.7e-19 69.2 2.5 3.5e-10 39.3 0.3 2.5 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KFM07869.1 - 5e-16 57.5 4.4 3.2e-06 26.5 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFM07869.1 - 1.3e-13 49.7 3.2 9.4e-06 25.1 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat FKBP_C PF00254.23 KFM07869.1 - 3e-11 43.1 0.0 6.4e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_16 PF13432.1 KFM07869.1 - 5e-11 42.9 0.4 1.8e-08 34.7 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFM07869.1 - 3.7e-09 36.3 3.1 2.6e-06 27.2 0.3 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KFM07869.1 - 1.5e-08 34.4 2.1 0.00076 19.3 0.1 2.7 2 0 0 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.1 KFM07869.1 - 1.7e-08 34.3 0.1 0.0004 20.7 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFM07869.1 - 1.5e-07 30.6 2.5 7.6e-05 22.2 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFM07869.1 - 8.3e-07 28.7 0.0 7.5e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFM07869.1 - 1e-06 28.9 0.7 4.5e-06 26.9 0.3 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFM07869.1 - 1.1e-06 27.9 0.5 0.0018 17.9 0.0 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat Apc3 PF12895.2 KFM07869.1 - 0.00013 22.0 0.4 0.0014 18.6 0.0 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 KFM07869.1 - 0.00014 21.7 0.4 0.0055 16.8 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFM07869.1 - 0.0013 19.0 0.6 0.11 13.0 0.0 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat NARP1 PF12569.3 KFM07869.1 - 0.0018 17.1 0.2 0.0023 16.7 0.1 1.1 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_10 PF13374.1 KFM07869.1 - 0.0037 17.1 5.3 1.2 9.2 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 KFM07869.1 - 0.027 14.7 0.1 0.056 13.6 0.1 1.5 1 1 0 1 1 1 0 Alkyl sulfatase dimerisation MIT PF04212.13 KFM07869.1 - 0.038 13.8 1.4 3.4 7.6 0.0 2.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_20 PF14561.1 KFM07869.1 - 0.094 12.8 0.2 0.32 11.1 0.1 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat SPO22 PF08631.5 KFM07869.1 - 1.2 8.2 4.8 6.2 5.8 0.8 2.8 2 1 1 3 3 3 0 Meiosis protein SPO22/ZIP4 like KxDL PF10241.4 KFM07870.1 - 8.2e-27 92.9 1.4 1.3e-26 92.3 1.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein BSMAP PF12280.3 KFM07871.1 - 4.9e-14 52.7 0.0 5.2e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Brain specific membrane anchored protein DUF997 PF06196.7 KFM07871.1 - 0.023 14.1 0.6 0.029 13.8 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF997) Kelch_1 PF01344.20 KFM07872.1 - 7e-42 140.7 15.0 9.9e-09 34.6 0.6 6.2 5 1 0 5 5 5 5 Kelch motif Kelch_6 PF13964.1 KFM07872.1 - 1.1e-34 117.1 4.1 3e-07 30.3 0.0 5.7 3 1 3 6 6 6 5 Kelch motif BACK PF07707.10 KFM07872.1 - 1.9e-25 88.7 0.5 3.6e-25 87.7 0.4 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_4 PF13418.1 KFM07872.1 - 5.7e-19 67.6 1.1 0.0055 16.4 0.0 5.6 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.10 KFM07872.1 - 2.1e-18 65.2 8.8 0.00012 21.6 0.0 6.2 6 1 0 6 6 6 3 Kelch motif Kelch_3 PF13415.1 KFM07872.1 - 1.2e-13 50.7 0.3 0.012 15.7 0.0 5.8 5 0 0 5 5 5 4 Galactose oxidase, central domain BTB PF00651.26 KFM07872.1 - 9e-13 48.1 0.0 1.9e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_5 PF13854.1 KFM07872.1 - 2.3e-11 43.3 8.7 0.16 11.9 0.1 5.7 6 0 0 6 6 6 4 Kelch motif PQQ_3 PF13570.1 KFM07872.1 - 0.024 14.8 0.1 4.1 7.7 0.1 3.8 4 0 0 4 4 4 0 PQQ-like domain TORC_M PF12885.2 KFM07873.1 - 3.3e-70 234.6 9.8 3.3e-70 234.6 6.8 2.8 3 1 1 4 4 4 1 Transducer of regulated CREB activity middle domain TORC_C PF12886.2 KFM07873.1 - 1.4e-34 118.1 1.8 3.2e-34 116.9 1.3 1.7 1 0 0 1 1 1 1 Transducer of regulated CREB activity, C terminus TSP_C PF05735.7 KFM07874.1 - 5.7e-107 355.8 1.8 8e-107 355.3 1.3 1.2 1 0 0 1 1 1 1 Thrombospondin C-terminal region TSP_3 PF02412.13 KFM07874.1 - 1.7e-54 180.9 133.2 1.6e-11 43.4 10.4 9.4 7 2 1 8 8 8 8 Thrombospondin type 3 repeat EGF_CA PF07645.10 KFM07874.1 - 4.2e-18 65.0 43.9 3.5e-09 36.4 4.7 5.5 4 0 0 4 4 4 4 Calcium-binding EGF domain COMP PF11598.3 KFM07874.1 - 3.8e-15 55.6 1.6 9.6e-15 54.3 1.1 1.8 1 0 0 1 1 1 1 Cartilage oligomeric matrix protein cEGF PF12662.2 KFM07874.1 - 7.5e-11 41.4 26.5 1.7e-05 24.3 1.9 6.0 4 0 0 4 4 4 3 Complement Clr-like EGF-like EGF_3 PF12947.2 KFM07874.1 - 4.8e-05 23.2 57.1 0.00036 20.4 3.0 6.1 6 0 0 6 6 6 4 EGF domain hEGF PF12661.2 KFM07874.1 - 9.2e-05 22.2 15.7 0.68 10.1 0.5 6.0 4 0 0 4 4 4 3 Human growth factor-like EGF EGF_MSP1_1 PF12946.2 KFM07874.1 - 1.1 9.0 25.8 0.02 14.6 2.5 4.6 4 0 0 4 4 4 0 MSP1 EGF domain 1 EGF PF00008.22 KFM07874.1 - 8 6.5 50.6 0.032 14.1 1.9 5.5 4 0 0 4 4 4 0 EGF-like domain UPF1_Zn_bind PF09416.5 KFM07875.1 - 1.9e-73 245.0 7.9 4.5e-73 243.8 5.2 1.9 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 KFM07875.1 - 3.1e-61 206.2 0.0 5.5e-61 205.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KFM07875.1 - 6.8e-52 176.3 0.5 1.1e-51 175.6 0.3 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFM07875.1 - 2.4e-14 52.8 0.2 6.4e-14 51.4 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KFM07875.1 - 3.8e-12 46.2 0.1 1.3e-10 41.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 KFM07875.1 - 2.4e-07 30.7 0.0 4.9e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 KFM07875.1 - 0.00016 20.7 0.1 0.0036 16.3 0.0 2.7 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.9 KFM07875.1 - 0.00038 20.1 0.0 0.00092 18.8 0.0 1.7 1 0 0 1 1 1 1 Helicase KaiC PF06745.8 KFM07875.1 - 0.00052 19.1 0.0 0.014 14.5 0.0 2.2 2 0 0 2 2 2 1 KaiC SRP54 PF00448.17 KFM07875.1 - 0.0043 16.5 0.0 0.0084 15.5 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain UvrD-helicase PF00580.16 KFM07875.1 - 0.014 14.6 0.1 0.7 9.1 0.0 2.7 2 1 1 3 3 3 0 UvrD/REP helicase N-terminal domain PIF1 PF05970.9 KFM07875.1 - 0.038 12.9 0.0 4.1 6.2 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase AAA_16 PF13191.1 KFM07875.1 - 0.038 13.9 0.0 0.072 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 KFM07875.1 - 0.046 13.1 0.0 0.094 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 KFM07875.1 - 0.048 13.1 0.0 0.13 11.6 0.0 1.8 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_10 PF12846.2 KFM07875.1 - 0.054 12.9 0.0 0.09 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain UvrD_C_2 PF13538.1 KFM07875.1 - 0.094 12.8 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Ribosomal_S13_N PF08069.7 KFM07875.1 - 0.16 11.8 0.0 0.49 10.2 0.0 1.8 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain AAA PF00004.24 KFM07875.1 - 0.18 12.0 0.0 0.39 10.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TGF_beta PF00019.15 KFM07876.1 - 1.4e-42 144.1 0.2 2.6e-42 143.3 0.1 1.4 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.13 KFM07876.1 - 3.3e-15 56.0 0.0 5.8e-15 55.2 0.0 1.4 2 0 0 2 2 2 1 TGF-beta propeptide TRAM_LAG1_CLN8 PF03798.11 KFM07878.1 - 9.5e-36 123.2 26.8 1.1e-35 123.0 18.6 1.0 1 0 0 1 1 1 1 TLC domain Coatomer_E PF04733.9 KFM07879.1 - 4.8e-115 383.7 4.9 5.4e-115 383.5 3.4 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 KFM07879.1 - 4.8e-10 39.6 8.2 6.9e-05 23.0 0.2 3.4 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFM07879.1 - 4.1e-09 36.2 5.2 0.0024 18.3 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 KFM07879.1 - 5.3e-08 32.8 3.5 0.00091 19.3 0.1 2.8 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 KFM07879.1 - 6e-07 29.9 0.2 0.0023 18.5 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFM07879.1 - 8.2e-07 28.4 3.4 0.00084 19.0 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFM07879.1 - 1.2e-06 28.3 2.2 0.0039 17.0 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 KFM07879.1 - 2.1e-06 27.2 0.3 0.0004 19.9 0.0 3.0 1 1 0 2 2 2 1 TPR repeat TPR_7 PF13176.1 KFM07879.1 - 0.00061 19.3 3.2 0.0035 17.0 0.0 3.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFM07879.1 - 0.00073 19.0 4.0 0.0058 16.1 0.1 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFM07879.1 - 0.0097 16.3 3.9 1.5 9.4 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 KFM07879.1 - 0.013 15.4 3.7 0.013 15.3 0.1 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFM07879.1 - 0.033 13.9 0.9 6.1 6.8 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.15 KFM07879.1 - 0.038 13.9 2.8 8.3 6.6 0.0 3.9 4 0 0 4 4 4 0 PPR repeat PPR_2 PF13041.1 KFM07879.1 - 0.054 13.4 4.3 11 6.1 0.4 3.7 4 0 0 4 4 4 0 PPR repeat family TPR_21 PF09976.4 KFM07879.1 - 0.084 12.8 8.2 7.3 6.5 2.9 3.3 1 1 1 2 2 2 0 Tetratricopeptide repeat CysG_dimeriser PF10414.4 KFM07879.1 - 0.11 11.9 0.0 0.29 10.6 0.0 1.7 1 0 0 1 1 1 0 Sirohaem synthase dimerisation region DUF964 PF06133.6 KFM07879.1 - 0.14 12.2 2.9 1.1 9.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF964) DEAD PF00270.24 KFM07880.1 - 7.1e-26 90.7 0.8 1.2e-25 89.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFM07880.1 - 1.2e-23 82.7 0.0 2.8e-23 81.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KFM07880.1 - 0.11 12.6 1.2 1.4 9.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain Atg14 PF10186.4 KFM07880.1 - 1.4 7.7 12.5 3 6.7 7.1 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 WH1 PF00568.18 KFM07881.1 - 7.8e-37 125.3 0.2 1.5e-36 124.5 0.1 1.5 1 0 0 1 1 1 1 WH1 domain GAS PF13851.1 KFM07881.1 - 0.0084 15.3 7.6 0.0084 15.3 5.3 2.8 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding Flu_M1_C PF08289.6 KFM07881.1 - 0.071 13.1 0.5 0.071 13.1 0.3 2.3 3 1 0 3 3 3 0 Influenza Matrix protein (M1) C-terminal domain DUF4288 PF14119.1 KFM07881.1 - 0.14 12.2 3.2 0.17 12.0 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4288) Reo_sigmaC PF04582.7 KFM07881.1 - 0.34 10.0 7.5 0.98 8.5 1.3 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF3461 PF11944.3 KFM07881.1 - 0.58 10.0 11.0 0.036 13.9 2.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3461) RTBV_P46 PF06216.6 KFM07881.1 - 1.6 7.5 6.3 4.4 6.0 0.7 2.2 1 1 1 2 2 2 0 Rice tungro bacilliform virus P46 protein Cep57_MT_bd PF06657.8 KFM07881.1 - 2.2 8.2 14.1 1.3 9.0 3.2 2.7 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Bap31 PF05529.7 KFM07881.1 - 6.7 6.1 19.5 0.6 9.5 6.4 3.5 2 1 2 4 4 4 0 B-cell receptor-associated protein 31-like Surp PF01805.15 KFM07882.1 - 2.5e-19 68.6 0.4 5.9e-12 45.0 0.0 2.7 2 0 0 2 2 2 2 Surp module G-patch PF01585.18 KFM07882.1 - 2.5e-14 52.7 4.2 4.6e-14 51.9 2.9 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KFM07882.1 - 0.0033 17.2 2.6 0.0033 17.2 1.8 2.4 2 0 0 2 2 2 1 DExH-box splicing factor binding site Arm PF00514.18 KFM07883.1 - 2.8e-11 42.8 8.2 0.059 13.2 0.0 5.8 5 0 0 5 5 5 5 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.4 KFM07883.1 - 0.0024 17.5 4.1 0.67 9.7 0.1 4.4 3 1 2 5 5 5 2 Spinocerebellar ataxia type 10 protein domain UNC45-central PF11701.3 KFM07883.1 - 0.0088 15.7 0.0 0.045 13.4 0.0 2.2 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central UBA_3 PF09288.5 KFM07883.1 - 0.037 13.6 0.1 0.099 12.2 0.1 1.7 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Tmemb_161AB PF10268.4 KFM07884.1 - 7.6e-195 648.0 0.2 8.5e-195 647.8 0.1 1.0 1 0 0 1 1 1 1 Predicted transmembrane protein 161AB NEP PF10167.4 KFM07885.1 - 2.9e-18 65.6 0.0 3.1e-18 65.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein RasGAP_C PF03836.10 KFM07886.1 - 0.0062 16.2 0.1 0.0062 16.2 0.0 1.0 1 0 0 1 1 1 1 RasGAP C-terminus F5_F8_type_C PF00754.20 KFM07887.1 - 5.3e-05 23.0 0.0 8.8e-05 22.3 0.0 1.4 2 0 0 2 2 2 1 F5/8 type C domain Xlink PF00193.12 KFM07888.1 - 3.2e-61 203.4 0.8 1.3e-32 111.6 0.0 2.1 2 0 0 2 2 2 2 Extracellular link domain V-set PF07686.12 KFM07888.1 - 8.4e-12 44.9 0.0 1.4e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 KFM07888.1 - 2.9e-07 30.2 0.0 5.9e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM07888.1 - 1.2e-06 28.5 0.0 2.5e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Chordopox_A33R PF05966.7 KFM07888.1 - 0.00069 18.4 0.6 0.0026 16.5 0.0 1.9 2 0 0 2 2 2 1 Chordopoxvirus A33R protein Ig_3 PF13927.1 KFM07888.1 - 0.0018 18.7 0.0 0.012 16.1 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.20 KFM07888.1 - 0.01 15.9 0.0 0.039 14.0 0.0 2.0 1 1 0 1 1 1 0 Immunoglobulin domain V-set_CD47 PF08204.6 KFM07888.1 - 0.048 13.4 0.0 0.082 12.6 0.0 1.3 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain Lectin_C PF00059.16 KFM07888.1 - 0.23 12.1 1.4 12 6.5 0.1 2.3 2 0 0 2 2 2 0 Lectin C-type domain DUF2781 PF10914.3 KFM07889.1 - 2.2e-37 128.1 15.9 3.8e-34 117.6 6.3 2.3 2 1 0 2 2 2 2 Protein of unknown function (DUF2781) DUF2910 PF11139.3 KFM07889.1 - 0.047 12.8 1.2 0.092 11.8 0.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2910) Surp PF01805.15 KFM07890.1 - 1.1e-31 108.2 6.2 1.6e-16 59.6 0.1 2.8 3 0 0 3 3 3 2 Surp module G-patch PF01585.18 KFM07890.1 - 7.2e-15 54.5 3.0 7.2e-15 54.5 2.1 1.9 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 KFM07890.1 - 2.7e-07 30.3 0.4 2.7e-07 30.3 0.3 3.6 4 0 0 4 4 4 1 DExH-box splicing factor binding site Tuberculin PF12198.3 KFM07890.1 - 0.037 13.9 0.0 4.4 7.2 0.0 2.4 2 0 0 2 2 2 0 Theoretical tuberculin protein SWIRM PF04433.12 KFM07890.1 - 6.8 6.9 8.7 9 6.5 0.3 4.0 3 1 0 4 4 4 0 SWIRM domain Cohesin_load PF10345.4 KFM07891.1 - 2e-111 373.1 12.0 2.3e-111 372.9 8.3 1.0 1 0 0 1 1 1 1 Cohesin loading factor TPR_11 PF13414.1 KFM07891.1 - 4.5e-11 42.2 7.7 0.00071 19.1 0.0 5.3 6 1 1 7 7 7 3 TPR repeat TPR_12 PF13424.1 KFM07891.1 - 6.7e-10 38.7 13.8 0.00056 19.8 0.1 5.8 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 KFM07891.1 - 2.7e-07 29.9 6.9 0.17 11.8 0.1 7.1 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFM07891.1 - 0.0002 20.9 4.8 0.64 9.9 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFM07891.1 - 0.00021 21.6 2.6 1.2 9.9 0.0 6.4 5 2 3 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFM07891.1 - 0.00046 20.4 6.4 0.006 16.9 0.1 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat Apc3 PF12895.2 KFM07891.1 - 0.00094 19.2 7.0 0.4 10.8 0.0 4.5 3 2 3 6 6 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 KFM07891.1 - 0.0023 17.7 0.6 2.1 8.3 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat HemY_N PF07219.8 KFM07891.1 - 0.0029 17.1 0.1 0.023 14.2 0.0 2.4 2 1 0 2 2 2 1 HemY protein N-terminus TPR_1 PF00515.23 KFM07891.1 - 0.003 17.0 5.1 1.6 8.4 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_21 PF09976.4 KFM07891.1 - 0.1 12.5 0.3 8.2 6.3 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Ig_2 PF13895.1 KFM07892.1 - 2.8e-10 40.1 0.0 2e-09 37.4 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.1 KFM07892.1 - 9.3e-09 35.6 0.0 3.1e-08 33.9 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 KFM07892.1 - 1e-07 31.7 0.0 7.3e-07 28.9 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin I-set domain DUF4480 PF13715.1 KFM07892.1 - 1.4e-05 25.0 0.0 2.8e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4480) ig PF00047.20 KFM07892.1 - 0.0034 17.4 0.2 0.0095 16.0 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.12 KFM07892.1 - 0.022 14.6 0.0 0.47 10.3 0.0 2.6 2 1 0 2 2 2 0 Immunoglobulin V-set domain DDA1 PF10172.4 KFM07893.1 - 1.1e-35 121.3 0.2 1.5e-35 120.8 0.1 1.2 1 0 0 1 1 1 1 Det1 complexing ubiquitin ligase Ribosomal_L34 PF00468.12 KFM07894.1 - 7.7e-20 70.3 2.5 1.1e-19 69.7 1.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 Abhydrolase_6 PF12697.2 KFM07895.1 - 1.7e-35 122.9 0.0 2.5e-35 122.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFM07895.1 - 3.5e-21 75.8 0.1 9.2e-14 51.5 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFM07895.1 - 3.4e-19 69.0 0.0 1.8e-18 66.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KFM07895.1 - 6.8e-07 29.0 0.1 5.1e-06 26.2 0.0 2.2 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 KFM07895.1 - 5.7e-05 22.6 0.4 0.23 10.8 0.0 3.0 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.5 KFM07895.1 - 0.015 15.1 0.0 0.049 13.5 0.0 1.9 1 0 0 1 1 1 0 TAP-like protein Peptidase_S9 PF00326.16 KFM07895.1 - 0.02 14.0 0.0 0.17 11.0 0.0 2.2 2 1 0 2 2 2 0 Prolyl oligopeptidase family FSH1 PF03959.8 KFM07895.1 - 0.021 14.2 0.0 0.063 12.7 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase (FSH1) DLH PF01738.13 KFM07895.1 - 0.033 13.4 0.0 5.2 6.2 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_8 PF06259.7 KFM07895.1 - 0.055 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF678 PF05077.7 KFM07895.1 - 0.099 12.6 0.2 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF678) Lipase_3 PF01764.20 KFM07895.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Ndr PF03096.9 KFM07895.1 - 0.13 10.6 0.0 2 6.7 0.0 2.0 2 0 0 2 2 2 0 Ndr family Ser_hydrolase PF06821.8 KFM07895.1 - 0.15 11.6 0.0 12 5.4 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase BAAT_C PF08840.6 KFM07895.1 - 0.15 11.7 0.0 1.4 8.5 0.0 2.4 2 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal SK_channel PF03530.9 KFM07896.1 - 1.8e-18 66.4 1.0 4.3e-18 65.2 0.0 2.1 2 0 0 2 2 2 1 Calcium-activated SK potassium channel Ion_trans_2 PF07885.11 KFM07896.1 - 3.9e-11 42.5 3.7 9.1e-11 41.3 2.6 1.7 1 0 0 1 1 1 1 Ion channel DUF1014 PF06244.7 KFM07897.1 - 5.2e-45 152.5 6.9 5.2e-45 152.5 4.8 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF1014) HMG_box PF00505.14 KFM07897.1 - 0.0022 18.1 0.7 0.0022 18.1 0.5 2.7 2 1 1 3 3 3 1 HMG (high mobility group) box Asp-B-Hydro_N PF05279.6 KFM07897.1 - 3.2 7.5 21.7 3.8 7.2 15.0 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Ribosomal_L7Ae PF01248.21 KFM07900.1 - 1.4e-08 34.1 0.0 2e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family G-gamma PF00631.17 KFM07901.1 - 1.8e-11 43.5 0.0 2e-11 43.4 0.0 1.0 1 0 0 1 1 1 1 GGL domain Ras PF00071.17 KFM07902.1 - 1.2e-49 167.7 0.2 1.5e-49 167.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM07902.1 - 7.3e-23 81.3 0.3 1.2e-22 80.5 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFM07902.1 - 1.2e-07 31.1 0.0 1.7e-07 30.6 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFM07902.1 - 3.6e-05 23.2 0.1 6.7e-05 22.4 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KFM07902.1 - 0.0011 18.1 0.5 0.0024 17.1 0.3 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit ArgK PF03308.11 KFM07902.1 - 0.0017 17.2 0.3 0.27 10.0 0.1 2.2 2 0 0 2 2 2 2 ArgK protein Gtr1_RagA PF04670.7 KFM07902.1 - 0.0036 16.4 0.1 0.0045 16.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFM07902.1 - 0.0036 17.2 0.0 0.0072 16.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KFM07902.1 - 0.015 15.4 0.1 0.2 11.8 0.1 2.6 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 KFM07902.1 - 0.033 13.3 0.8 0.1 11.7 0.1 2.1 2 1 1 3 3 3 0 Protein of unknown function, DUF258 DUF2408 PF10303.4 KFM07902.1 - 0.036 14.1 2.0 0.84 9.7 0.0 2.4 1 1 1 3 3 3 0 Protein of unknown function (DUF2408) FeoB_N PF02421.13 KFM07902.1 - 0.052 12.8 0.3 0.2 10.8 0.2 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B Arch_ATPase PF01637.13 KFM07902.1 - 0.053 13.2 0.7 0.14 11.8 0.4 1.9 1 1 0 1 1 1 0 Archaeal ATPase DAP3 PF10236.4 KFM07902.1 - 0.067 12.1 0.0 0.85 8.4 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_24 PF13479.1 KFM07902.1 - 0.07 12.7 0.2 0.092 12.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_32 PF13654.1 KFM07902.1 - 0.096 11.3 1.2 0.94 8.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain Guanylate_kin PF00625.16 KFM07902.1 - 0.1 12.0 1.0 0.85 9.0 0.1 2.2 1 1 1 2 2 2 0 Guanylate kinase Zip PF02535.17 KFM07903.1 - 3.9e-54 183.7 9.1 5e-54 183.4 6.3 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Cas_Csy2 PF09614.5 KFM07903.1 - 0.016 14.4 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy2) Ninjurin PF04923.7 KFM07903.1 - 0.11 12.2 0.5 29 4.4 0.0 3.2 2 1 0 2 2 2 0 Ninjurin DUF1129 PF06570.6 KFM07903.1 - 2.7 7.2 5.6 0.35 10.1 0.7 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) TPR_1 PF00515.23 KFM07904.1 - 1e-27 94.5 7.2 3.1e-10 39.2 0.0 3.6 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 KFM07904.1 - 5.2e-26 90.0 5.7 2.7e-18 65.3 0.8 2.6 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KFM07904.1 - 5.5e-20 69.6 5.6 4.2e-06 26.2 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFM07904.1 - 1.1e-15 56.4 3.0 3.1e-06 26.9 0.2 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFM07904.1 - 5.1e-14 50.9 3.3 9.5e-06 25.0 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFM07904.1 - 2.8e-13 50.1 2.3 1.3e-07 32.0 0.1 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFM07904.1 - 2.1e-12 45.8 0.3 0.0015 18.2 0.0 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFM07904.1 - 6.4e-11 42.4 0.5 2.7e-07 30.8 0.0 3.4 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFM07904.1 - 6.9e-11 41.7 0.2 0.002 18.5 0.0 4.4 3 1 2 5 5 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFM07904.1 - 5e-10 39.1 1.4 2.3e-08 33.8 0.2 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFM07904.1 - 4.4e-05 23.2 0.0 0.02 14.7 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TOM20_plant PF06552.7 KFM07904.1 - 0.00011 21.8 0.9 0.26 10.8 0.0 3.1 3 1 0 3 3 3 2 Plant specific mitochondrial import receptor subunit TOM20 Fis1_TPR_C PF14853.1 KFM07904.1 - 0.00014 21.6 4.6 0.077 12.8 0.0 3.3 3 1 1 4 4 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 KFM07904.1 - 0.00042 20.5 0.8 1.3 9.6 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat NARP1 PF12569.3 KFM07904.1 - 0.0012 17.6 0.0 1.2 7.8 0.0 2.2 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 Apc3 PF12895.2 KFM07904.1 - 0.0018 18.3 1.6 0.021 14.9 0.7 2.5 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.12 KFM07904.1 - 0.0027 18.0 0.2 0.55 10.5 0.0 2.5 1 1 1 2 2 2 1 Bacterial transcriptional activator domain TPR_15 PF13429.1 KFM07904.1 - 0.033 13.2 0.0 1.8 7.5 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 KFM07904.1 - 0.045 13.6 0.3 13 5.8 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF627 PF04781.7 KFM07904.1 - 0.057 13.0 3.3 0.85 9.2 0.1 2.7 2 1 1 3 3 2 0 Protein of unknown function (DUF627) MIT PF04212.13 KFM07904.1 - 0.2 11.5 4.7 6.8 6.6 0.1 3.7 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain XPC-binding PF09280.6 KFM07904.1 - 0.27 10.7 10.9 0.52 9.7 2.6 2.6 2 0 0 2 2 2 0 XPC-binding domain NTR PF01759.16 KFM07905.1 - 8.1e-12 44.6 0.0 8.8e-12 44.5 0.0 1.0 1 0 0 1 1 1 1 UNC-6/NTR/C345C module TB2_DP1_HVA22 PF03134.14 KFM07906.1 - 4.4e-29 100.0 4.7 5.1e-29 99.8 3.2 1.1 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Ribosomal_S19 PF00203.16 KFM07907.1 - 5.3e-36 122.0 0.5 6.5e-36 121.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 RRM_1 PF00076.17 KFM07908.1 - 2e-40 136.2 0.2 1.3e-19 69.5 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM07908.1 - 4.6e-36 122.6 0.1 5.2e-17 61.5 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM07908.1 - 1.3e-18 66.5 0.1 9.4e-09 35.0 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFM07908.1 - 7.8e-05 22.3 0.2 0.19 11.5 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif NID PF07292.8 KFM07908.1 - 0.017 15.1 0.0 1.1 9.3 0.0 2.6 3 0 0 3 3 3 0 Nmi/IFP 35 domain (NID) CSD PF00313.17 KFM07908.1 - 0.025 14.3 1.3 1.5 8.6 0.1 2.4 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain DUF4651 PF15513.1 KFM07908.1 - 0.036 13.5 0.2 9.1 5.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) Oxidored_q6 PF01058.17 KFM07909.1 - 9e-07 28.5 0.1 0.00022 20.8 0.0 2.1 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Pkinase PF00069.20 KFM07910.1 - 1.8e-59 201.0 0.0 2.1e-59 200.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM07910.1 - 2.5e-20 72.6 0.0 3.2e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM07910.1 - 0.00052 19.0 0.0 0.00092 18.2 0.0 1.4 1 1 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 KFM07910.1 - 0.01 15.1 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 KFM07910.1 - 0.062 12.3 0.0 0.091 11.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFM07910.1 - 0.072 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Ephrin PF00812.12 KFM07911.1 - 4.4e-44 149.5 0.1 4.9e-44 149.3 0.1 1.0 1 0 0 1 1 1 1 Ephrin RRM_1 PF00076.17 KFM07912.1 - 2.2e-26 91.2 0.1 3.6e-26 90.5 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM07912.1 - 7e-18 64.3 0.1 1.1e-17 63.7 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM07912.1 - 2.2e-11 43.4 0.1 3.5e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFM07912.1 - 0.063 13.1 0.2 0.098 12.5 0.1 1.3 1 0 0 1 1 1 0 RNA binding motif HemX PF04375.9 KFM07914.1 - 0.036 12.6 2.1 0.04 12.5 1.4 1.0 1 0 0 1 1 1 0 HemX DUF4140 PF13600.1 KFM07914.1 - 0.22 11.9 2.5 0.24 11.8 1.7 1.1 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) KfrA_N PF11740.3 KFM07914.1 - 0.32 11.4 6.7 0.39 11.1 4.7 1.1 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term ATP-synt_DE PF00401.15 KFM07914.1 - 0.42 10.5 11.1 1.9 8.4 7.5 2.0 1 1 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Spidroin_MaSp PF11260.3 KFM07914.1 - 0.6 10.2 3.7 0.74 9.9 2.5 1.2 1 0 0 1 1 1 0 Major ampullate spidroin 1 and 2 Pro_Al_protease PF02983.9 KFM07914.1 - 9.1 6.3 12.1 5.8e+02 0.5 8.3 2.7 1 1 0 1 1 1 0 Alpha-lytic protease prodomain Pkinase PF00069.20 KFM07915.1 - 4.3e-56 189.9 0.0 5.9e-56 189.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM07915.1 - 2.5e-32 111.9 0.0 6.6e-32 110.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM07915.1 - 4.7e-10 38.9 0.0 6.3e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFM07915.1 - 0.03 14.0 0.0 1 9.0 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Helicase_C_4 PF13871.1 KFM07916.1 - 4.8e-116 387.0 0.0 7.4e-116 386.4 0.0 1.3 1 0 0 1 1 1 1 Helicase_C-like AAA_34 PF13872.1 KFM07916.1 - 7.4e-101 336.9 0.0 1.9e-83 279.7 0.0 2.2 2 0 0 2 2 2 2 P-loop containing NTP hydrolase pore-1 Helicase_C PF00271.26 KFM07916.1 - 0.00098 18.9 0.0 0.0031 17.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RNA_pol_Rpb5_C PF01191.14 KFM07917.1 - 1.6e-35 120.5 0.4 2.4e-35 119.9 0.3 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain EIAV_Rev PF11129.3 KFM07917.1 - 0.085 12.8 0.0 0.094 12.6 0.0 1.1 1 0 0 1 1 1 0 Rev protein of equine infectious anaemia virus MA-Mit PF09245.5 KFM07917.1 - 0.12 11.5 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Mycoplasma arthritidis-derived mitogen Calponin PF00402.13 KFM07918.1 - 4.7e-39 131.3 20.3 1.9e-14 52.6 0.8 4.0 3 0 0 3 3 3 3 Calponin family repeat CH PF00307.26 KFM07918.1 - 4.4e-18 65.3 0.1 8.5e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFM07918.1 - 0.001 18.6 0.0 0.0019 17.8 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain CDC24 PF06395.6 KFM07918.1 - 0.1 12.6 0.1 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 CDC24 Calponin Membralin PF09746.4 KFM07919.1 - 6.1e-202 670.5 6.6 7.8e-202 670.2 4.6 1.1 1 0 0 1 1 1 1 Tumour-associated protein NVEALA PF14055.1 KFM07919.1 - 1.7 8.4 0.0 1.7 8.4 0.0 2.9 4 0 0 4 4 4 0 NVEALA protein ERGIC_N PF13850.1 KFM07919.1 - 7 6.6 6.6 2.4 8.2 0.4 2.8 3 0 0 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF4140 PF13600.1 KFM07920.1 - 0.012 16.1 0.9 0.012 16.0 0.7 1.3 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) HR1 PF02185.11 KFM07920.1 - 0.014 15.1 0.5 0.022 14.5 0.3 1.3 1 0 0 1 1 1 0 Hr1 repeat DUF2346 PF09803.4 KFM07920.1 - 0.028 14.2 0.3 0.039 13.7 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2346) DUF3348 PF11828.3 KFM07920.1 - 0.12 11.7 1.1 0.21 10.9 0.6 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3348) WD40 PF00400.27 KFM07921.1 - 3.2e-24 83.8 6.7 9.9e-11 41.1 0.1 5.6 5 1 0 5 5 5 4 WD domain, G-beta repeat WD40_alt PF14077.1 KFM07921.1 - 2.6e-17 62.1 0.5 4.5e-17 61.4 0.4 1.4 1 0 0 1 1 1 1 Alternative WD40 repeat motif Nup160 PF11715.3 KFM07921.1 - 0.032 12.3 0.3 0.16 10.0 0.1 1.8 1 1 1 2 2 2 0 Nucleoporin Nup120/160 CENP-T PF15511.1 KFM07922.1 - 0.0075 15.5 18.7 0.0099 15.1 13.0 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T SAPS PF04499.10 KFM07922.1 - 0.14 10.7 2.6 0.14 10.7 1.8 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.7 KFM07922.1 - 0.17 9.7 29.6 0.19 9.6 20.5 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 KFM07922.1 - 0.29 10.1 23.6 0.34 9.9 16.3 1.1 1 0 0 1 1 1 0 BUD22 Pilt PF15453.1 KFM07922.1 - 1.2 8.7 10.6 1.5 8.4 7.4 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Ycf1 PF05758.7 KFM07922.1 - 1.7 6.2 6.8 1.8 6.1 4.7 1.0 1 0 0 1 1 1 0 Ycf1 NOA36 PF06524.7 KFM07922.1 - 3.7 6.7 19.1 5.1 6.2 13.2 1.2 1 0 0 1 1 1 0 NOA36 protein DUF1510 PF07423.6 KFM07922.1 - 4 6.7 21.2 5.3 6.3 14.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2146 PF10220.4 KFM07922.1 - 4.8 5.0 12.1 5.7 4.7 8.4 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) DDHD PF02862.12 KFM07922.1 - 8 6.1 7.5 11 5.7 5.2 1.2 1 0 0 1 1 1 0 DDHD domain Med16 PF11635.3 KFM07923.1 - 3.4e-174 580.8 0.3 4.2e-174 580.5 0.2 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 WD40 PF00400.27 KFM07923.1 - 4.7e-07 29.4 2.4 2.3e-06 27.2 1.2 2.8 2 0 0 2 2 2 1 WD domain, G-beta repeat Trypsin PF00089.21 KFM07924.1 - 1.1e-17 64.4 0.0 1.2e-17 64.2 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 KFM07924.1 - 0.00015 21.1 0.0 0.00016 21.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) PAP2 PF01569.16 KFM07925.1 - 2.6e-11 43.3 4.0 4e-11 42.6 2.8 1.3 1 0 0 1 1 1 1 PAP2 superfamily RRM_5 PF13893.1 KFM07926.1 - 1.5e-49 165.6 2.0 2.6e-14 52.7 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM07926.1 - 1.4e-39 133.9 0.4 1.7e-10 40.6 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFM07926.1 - 4.6e-37 125.4 0.2 4.1e-10 39.1 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AKAP2_C PF15304.1 KFM07927.1 - 7.2e-58 196.8 21.4 7.2e-58 196.8 14.8 3.4 2 1 0 3 3 3 2 A-kinase anchor protein 2 C-terminus Trypsin PF00089.21 KFM07928.1 - 1e-53 182.1 0.0 1.3e-53 181.8 0.0 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 KFM07928.1 - 1.5e-05 24.4 0.0 2.4e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 KFM07928.1 - 0.00066 19.6 0.0 0.0019 18.1 0.0 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain zf-RING_2 PF13639.1 KFM07929.1 - 9.9e-16 57.3 7.6 9.9e-16 57.3 5.3 1.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFM07929.1 - 3.7e-08 33.2 7.0 3.7e-08 33.2 4.8 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM07929.1 - 5.2e-08 32.4 2.6 5.2e-08 32.4 1.8 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFM07929.1 - 5.9e-08 32.7 6.5 1.6e-07 31.3 4.5 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KFM07929.1 - 1.5e-07 31.0 5.8 1.5e-07 31.0 4.0 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KFM07929.1 - 3.1e-07 29.9 6.6 3.1e-07 29.9 4.6 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFM07929.1 - 6.1e-05 22.7 3.8 0.00017 21.3 2.6 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_3 PF14369.1 KFM07929.1 - 0.0016 18.3 0.5 0.0016 18.3 0.4 3.1 3 0 0 3 3 3 1 zinc-finger zf-RING_UBOX PF13445.1 KFM07929.1 - 0.0018 17.9 5.5 0.017 14.8 0.9 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.3 KFM07929.1 - 0.0089 15.5 3.2 0.019 14.4 2.2 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Opy2 PF09463.5 KFM07929.1 - 0.052 13.6 3.6 9.9 6.3 0.1 3.4 3 0 0 3 3 3 0 Opy2 protein Vps39_2 PF10367.4 KFM07929.1 - 0.057 13.5 0.8 11 6.2 0.3 2.3 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Rad50_zn_hook PF04423.9 KFM07929.1 - 0.18 11.2 6.9 0.3 10.5 0.1 2.8 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-RING_4 PF14570.1 KFM07929.1 - 0.68 9.5 11.1 2.3 7.8 0.1 2.9 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 KFM07929.1 - 1.2 9.2 5.5 2.3 8.3 3.8 1.5 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.24 KFM07929.1 - 2 8.1 10.5 2 8.1 4.2 2.4 2 0 0 2 2 2 0 PHD-finger FANCL_C PF11793.3 KFM07929.1 - 2.4 8.1 8.4 41 4.2 5.8 2.8 1 1 0 1 1 1 0 FANCL C-terminal domain DUF3678 PF12435.3 KFM07929.1 - 3.3 7.3 15.1 0.17 11.4 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) TF_Zn_Ribbon PF08271.7 KFM07929.1 - 7 6.0 7.8 13 5.1 0.1 3.1 3 0 0 3 3 3 0 TFIIB zinc-binding zf-C3HC4_4 PF15227.1 KFM07929.1 - 8.4 6.3 11.1 7.7 6.4 5.3 2.7 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING FGF PF00167.13 KFM07930.1 - 4.7e-32 110.3 0.0 5.2e-32 110.1 0.0 1.0 1 0 0 1 1 1 1 Fibroblast growth factor RNA_pol PF00940.14 KFM07931.1 - 4.5e-146 486.4 0.0 7.3e-146 485.7 0.0 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 KFM07931.1 - 1.4e-44 152.6 0.0 2.7e-44 151.7 0.0 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal PPR_3 PF13812.1 KFM07931.1 - 0.082 13.2 0.1 12 6.5 0.0 3.2 3 0 0 3 3 3 0 Pentatricopeptide repeat domain UQ_con PF00179.21 KFM07932.1 - 1.9e-30 105.1 0.1 2.4e-30 104.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFM07932.1 - 0.018 14.8 0.1 0.064 13.0 0.1 1.9 1 1 0 1 1 1 0 Prokaryotic E2 family B MFS_1 PF07690.11 KFM07933.1 - 8e-34 116.8 38.0 2.5e-33 115.2 26.1 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily PID PF00640.18 KFM07934.1 - 1.8e-29 102.5 0.0 2.6e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SH2 PF00017.19 KFM07934.1 - 1.4e-18 66.4 0.0 2.4e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 SH2 domain C2 PF00168.25 KFM07935.1 - 6.4e-10 38.7 0.0 1.1e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain ELM2 PF01448.19 KFM07936.1 - 3.2e-13 50.0 0.2 3.2e-13 50.0 0.1 2.1 2 0 0 2 2 2 1 ELM2 domain Myb_DNA-binding PF00249.26 KFM07936.1 - 3e-05 24.0 0.3 6.2e-05 22.9 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF2002 PF09400.5 KFM07936.1 - 0.085 12.5 0.2 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2002) SMN PF06003.7 KFM07936.1 - 4.3 6.3 14.8 0.51 9.3 0.5 3.4 3 1 0 3 3 3 0 Survival motor neuron protein (SMN) PAP2 PF01569.16 KFM07937.1 - 7.8e-24 83.7 1.3 1.4e-23 82.9 0.9 1.4 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 KFM07937.1 - 0.0058 16.8 2.6 0.0058 16.8 1.8 2.2 2 1 0 2 2 2 1 PAP2 superfamily C-terminal DUF389 PF04087.9 KFM07937.1 - 0.064 13.1 0.3 0.18 11.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF389) DUF2976 PF11190.3 KFM07937.1 - 0.25 10.9 3.3 0.16 11.4 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) TLE_N PF03920.10 KFM07938.1 - 1.6e-66 222.2 11.1 2.2e-66 221.7 7.7 1.2 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain HALZ PF02183.13 KFM07938.1 - 0.031 13.9 0.7 0.069 12.8 0.5 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper TLE_N PF03920.10 KFM07939.1 - 4.6e-67 223.9 11.0 6.9e-67 223.4 7.6 1.2 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain WD40 PF00400.27 KFM07939.1 - 1.3e-29 100.9 24.0 1e-07 31.5 0.2 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat HALZ PF02183.13 KFM07939.1 - 0.006 16.2 1.1 0.014 15.1 0.8 1.6 1 0 0 1 1 1 1 Homeobox associated leucine zipper Cu2_monoox_C PF03712.10 KFM07939.1 - 0.079 12.3 1.9 1.3 8.3 0.1 2.4 2 0 0 2 2 2 0 Copper type II ascorbate-dependent monooxygenase, C-terminal domain G-alpha PF00503.15 KFM07940.1 - 1.7e-117 392.4 1.9 1.9e-117 392.2 1.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KFM07940.1 - 4.4e-12 45.5 0.6 2.2e-11 43.3 0.2 2.2 2 1 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFM07940.1 - 0.0053 16.7 0.1 0.42 10.5 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KFM07940.1 - 0.036 14.5 0.1 5.8 7.4 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein Trypsin PF00089.21 KFM07941.1 - 8e-27 94.2 0.1 4.3e-19 68.9 0.0 2.0 1 1 1 2 2 2 2 Trypsin DUF1986 PF09342.6 KFM07941.1 - 0.064 12.5 0.0 0.076 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Peptidase_M28 PF04389.12 KFM07942.1 - 9.2e-12 45.0 0.0 1.6e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Nicastrin PF05450.10 KFM07942.1 - 1.1e-06 28.0 0.0 1.8e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Nicastrin RRM_1 PF00076.17 KFM07943.1 - 1.1e-37 127.4 0.0 3.6e-17 61.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM07943.1 - 1.3e-25 89.1 0.2 1.8e-11 43.8 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM07943.1 - 2.5e-24 84.8 0.0 4.8e-10 39.1 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 KFM07943.1 - 0.0035 17.2 0.0 0.24 11.4 0.0 2.5 2 0 0 2 2 2 1 RNA binding domain Nup35_RRM_2 PF14605.1 KFM07943.1 - 0.064 13.0 0.0 1.4 8.7 0.0 2.9 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif adh_short PF00106.20 KFM07944.1 - 4.8e-17 62.3 0.8 9.6e-16 58.1 0.6 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFM07944.1 - 3.1e-06 27.1 0.1 6.5e-05 22.8 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFM07944.1 - 0.0005 19.7 0.1 0.22 11.1 0.0 2.2 2 0 0 2 2 2 2 KR domain DUF1776 PF08643.5 KFM07944.1 - 0.00067 18.8 0.0 0.00091 18.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) SE PF08491.5 KFM07944.1 - 0.0026 16.6 0.0 0.0095 14.7 0.0 1.7 2 0 0 2 2 2 1 Squalene epoxidase Acetyltransf_7 PF13508.1 KFM07947.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_S8e PF01201.17 KFM07948.1 - 5.2e-37 126.9 15.2 3.8e-36 124.1 10.5 2.2 1 1 0 1 1 1 1 Ribosomal protein S8e GTP_EFTU PF00009.22 KFM07949.1 - 3.3e-63 212.5 0.1 5.2e-63 211.8 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 KFM07949.1 - 7e-28 96.3 0.0 2.9e-27 94.3 0.0 2.2 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.19 KFM07949.1 - 4.9e-24 84.0 0.0 1e-23 83.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.13 KFM07949.1 - 4.4e-13 48.8 0.0 1.1e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.20 KFM07949.1 - 5.2e-08 32.8 0.0 1.3e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KFM07949.1 - 0.0012 18.7 0.0 0.0035 17.2 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KFM07949.1 - 0.0038 17.7 0.0 0.01 16.3 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 KFM07949.1 - 0.0077 15.5 0.0 0.11 11.7 0.0 2.6 2 1 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.11 KFM07949.1 - 0.042 12.9 0.0 0.12 11.4 0.0 1.7 1 0 0 1 1 1 0 AIG1 family Glyco_hydro_20 PF00728.17 KFM07950.1 - 5e-87 292.3 0.0 6.1e-87 292.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 KFM07950.1 - 1.5e-14 54.7 0.0 2.7e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 KFM07950.1 - 0.0024 18.4 0.0 0.0038 17.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Kelch_1 PF01344.20 KFM07951.1 - 1.2e-49 165.6 3.5 1.5e-11 43.6 0.0 5.6 5 0 0 5 5 5 5 Kelch motif BACK PF07707.10 KFM07951.1 - 7.6e-30 102.7 1.9 2.3e-29 101.2 0.9 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.26 KFM07951.1 - 3.3e-29 101.0 0.2 6.5e-29 100.1 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.1 KFM07951.1 - 4e-29 99.5 4.3 4.5e-05 23.4 0.2 6.1 2 2 4 6 6 6 5 Kelch motif Kelch_4 PF13418.1 KFM07951.1 - 3e-23 81.3 1.2 3.6e-08 33.0 0.0 5.8 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.1 KFM07951.1 - 9.4e-23 79.7 0.6 3.8e-06 26.8 0.0 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.10 KFM07951.1 - 3e-21 74.2 2.6 0.00014 21.4 0.0 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.1 KFM07951.1 - 7.1e-18 64.1 1.2 8.5e-09 35.1 0.0 5.8 6 0 0 6 6 6 4 Kelch motif DUF3342 PF11822.3 KFM07951.1 - 3e-05 23.3 0.1 9.6e-05 21.6 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3342) PFU PF09070.6 KFM07951.1 - 0.13 12.2 0.1 0.66 9.9 0.0 2.2 3 0 0 3 3 3 0 PFU (PLAA family ubiquitin binding) RhoGEF PF00621.15 KFM07952.1 - 2.2e-33 115.6 6.9 2.2e-33 115.6 4.8 2.6 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.24 KFM07952.1 - 1.2e-06 28.6 0.0 9.7e-06 25.7 0.0 2.6 1 0 0 1 1 1 1 PH domain C1_1 PF00130.17 KFM07952.1 - 1.1e-05 25.0 10.3 3.6e-05 23.3 7.2 2.0 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Ank_4 PF13637.1 KFM07953.1 - 0.0015 18.9 0.0 0.004 17.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KFM07953.1 - 0.013 15.8 0.1 0.039 14.2 0.0 1.9 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank PF00023.25 KFM07953.1 - 0.019 14.7 0.1 0.13 12.1 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat Ank_3 PF13606.1 KFM07953.1 - 0.089 13.0 0.0 2.6 8.5 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeat UTP15_C PF09384.5 KFM07954.1 - 3.5e-48 163.0 0.1 5.4e-48 162.4 0.1 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 KFM07954.1 - 1.6e-29 100.6 6.5 1.1e-07 31.4 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat BBS2_Mid PF14783.1 KFM07954.1 - 1.2e-05 25.0 0.0 0.053 13.3 0.0 3.4 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Ank_2 PF12796.2 KFM07955.1 - 6.2e-32 109.7 0.1 1.7e-21 76.3 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFM07955.1 - 2.3e-29 99.7 0.1 5e-10 38.6 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 KFM07955.1 - 1.2e-27 95.7 0.4 3.9e-09 36.7 0.0 3.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM07955.1 - 3.6e-24 84.2 1.0 2.8e-09 36.9 0.1 3.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM07955.1 - 1.4e-22 77.5 0.0 3.4e-07 29.8 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat NAC PF01849.13 KFM07956.1 - 4.1e-24 83.8 0.3 6.3e-24 83.2 0.2 1.3 1 0 0 1 1 1 1 NAC domain LolA PF03548.10 KFM07956.1 - 0.086 12.4 0.6 0.11 12.0 0.4 1.2 1 0 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA DUF4526 PF15029.1 KFM07958.1 - 1.3e-114 381.5 0.4 1.4e-114 381.4 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4526) PIRT PF15099.1 KFM07958.1 - 0.0031 16.7 0.1 0.0048 16.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family DUF2371 PF10177.4 KFM07958.1 - 0.91 9.3 5.6 1.3 8.8 0.1 2.2 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2371) Tetraspannin PF00335.15 KFM07958.1 - 5.8 6.1 7.8 97 2.1 5.3 2.1 1 1 0 1 1 1 0 Tetraspanin family TMEM171 PF15471.1 KFM07959.1 - 2.9e-161 535.6 1.6 3.2e-161 535.4 1.1 1.0 1 0 0 1 1 1 1 Transmembrane protein family 171 PRA1 PF03208.14 KFM07959.1 - 2.1 7.6 7.9 0.16 11.2 0.3 2.5 3 0 0 3 3 3 0 PRA1 family protein DUF2371 PF10177.4 KFM07959.1 - 6.7 6.5 9.2 0.44 10.4 1.5 2.5 2 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) muHD PF10291.4 KFM07960.1 - 1.4e-69 234.1 0.3 2.3e-69 233.4 0.2 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 KFM07960.1 - 4.7e-18 65.1 10.2 5.7e-18 64.8 0.0 3.0 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain Prominin PF05478.6 KFM07960.1 - 0.098 10.1 5.9 0.17 9.3 4.1 1.3 1 0 0 1 1 1 0 Prominin DUF1664 PF07889.7 KFM07960.1 - 0.29 10.9 8.8 2.5 7.9 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF445 PF04286.7 KFM07960.1 - 1 8.8 9.7 1.6 8.1 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) HEAT PF02985.17 KFM07961.1 - 9.1e-34 112.5 11.2 0.0015 18.4 0.0 12.1 12 0 0 12 12 12 7 HEAT repeat HEAT_EZ PF13513.1 KFM07961.1 - 3.3e-30 103.7 1.9 2.2e-10 40.6 0.0 10.3 9 1 1 10 10 10 6 HEAT-like repeat HEAT_2 PF13646.1 KFM07961.1 - 4.6e-23 81.2 0.0 0.00032 20.9 0.0 6.6 3 3 7 10 10 10 8 HEAT repeats Arm PF00514.18 KFM07961.1 - 4.4e-16 58.0 3.4 0.011 15.5 0.0 7.8 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.2 KFM07961.1 - 9.7e-15 54.7 1.2 0.0015 18.8 0.1 6.5 5 2 2 7 7 7 4 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 KFM07961.1 - 4.1e-14 52.2 0.5 2.9e-13 49.5 0.0 2.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cnd1 PF12717.2 KFM07961.1 - 1.5e-13 51.0 4.4 0.00049 20.0 0.1 4.7 3 2 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 KFM07961.1 - 9.6e-10 37.3 3.5 0.0032 15.8 0.4 5.0 3 2 1 4 4 4 4 Adaptin N terminal region CLASP_N PF12348.3 KFM07961.1 - 5.2e-05 22.7 1.9 0.18 11.1 0.0 4.4 4 1 2 6 6 6 1 CLASP N terminal UNC45-central PF11701.3 KFM07961.1 - 9e-05 22.1 3.0 0.42 10.2 0.4 3.8 3 0 0 3 3 3 2 Myosin-binding striated muscle assembly central Dopey_N PF04118.9 KFM07961.1 - 0.0018 17.0 0.1 0.0061 15.3 0.1 1.9 1 0 0 1 1 1 1 Dopey, N-terminal Proteasom_PSMB PF10508.4 KFM07961.1 - 0.014 13.7 0.7 6.1 4.9 0.0 3.7 3 1 2 5 5 5 0 Proteasome non-ATPase 26S subunit MMS19_C PF12460.3 KFM07961.1 - 0.077 11.7 5.2 1.8 7.2 0.1 4.0 4 1 0 4 4 4 0 RNAPII transcription regulator C-terminal TAFH PF07531.9 KFM07961.1 - 0.34 10.5 1.7 17 5.1 0.0 4.0 5 0 0 5 5 5 0 NHR1 homology to TAF MRP-S27 PF10037.4 KFM07962.1 - 1.2e-06 27.7 0.3 2.3e-06 26.8 0.2 1.5 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 PPR_2 PF13041.1 KFM07962.1 - 4e-06 26.7 0.1 8.7e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 PPR repeat family TPR_19 PF14559.1 KFM07962.1 - 1.1e-05 25.6 0.6 0.39 11.0 0.0 3.9 2 1 2 4 4 4 3 Tetratricopeptide repeat PPR_3 PF13812.1 KFM07962.1 - 2.1e-05 24.4 0.1 0.001 19.1 0.0 3.4 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR PF01535.15 KFM07962.1 - 0.00039 20.2 0.1 0.002 17.9 0.0 2.3 2 0 0 2 2 2 1 PPR repeat Apc3 PF12895.2 KFM07962.1 - 0.0048 16.9 0.4 0.051 13.7 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 MRP-S27 PF10037.4 KFM07963.1 - 7.7e-107 357.8 8.7 8.6e-107 357.6 6.0 1.0 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 PPR_1 PF12854.2 KFM07963.1 - 0.0004 19.8 0.1 0.0017 17.8 0.0 1.9 2 0 0 2 2 2 1 PPR repeat PPR_2 PF13041.1 KFM07963.1 - 0.0013 18.6 0.1 0.0044 16.9 0.0 1.9 1 0 0 1 1 1 1 PPR repeat family PPR PF01535.15 KFM07963.1 - 0.002 17.9 0.1 0.0086 15.9 0.0 2.1 1 0 0 1 1 1 1 PPR repeat PPR_3 PF13812.1 KFM07963.1 - 0.003 17.7 0.0 0.039 14.2 0.0 2.6 2 0 0 2 2 2 1 Pentatricopeptide repeat domain Med1 PF10744.4 KFM07963.1 - 0.011 14.5 0.0 0.022 13.5 0.0 1.5 1 1 0 1 1 1 0 Mediator of RNA polymerase II transcription subunit 1 TPR_19 PF14559.1 KFM07963.1 - 0.019 15.3 0.0 0.32 11.3 0.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF2997 PF11211.3 KFM07963.1 - 0.22 10.9 0.0 0.22 10.9 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2997) MAP1B_neuraxin PF00414.12 KFM07964.1 - 7.2e-20 69.0 128.8 0.0068 15.6 1.7 15.9 15 0 0 15 15 15 14 Neuraxin and MAP1B repeat Tetraspannin PF00335.15 KFM07965.1 - 0.53 9.5 6.1 0.72 9.0 4.3 1.1 1 0 0 1 1 1 0 Tetraspanin family PGM_PMM_III PF02880.11 KFM07966.1 - 1.8e-28 98.8 0.0 3.4e-28 97.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_I PF02878.11 KFM07966.1 - 3.2e-14 52.5 0.0 5.3e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 KFM07966.1 - 6.6e-13 48.8 0.0 1.4e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KFM07966.1 - 0.0021 18.0 0.0 0.0045 16.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain cobW PF02492.14 KFM07967.1 - 4.2e-43 146.8 0.1 5.8e-43 146.3 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 KFM07967.1 - 1.6e-19 69.4 0.0 2.6e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.22 KFM07967.1 - 5e-05 22.8 0.4 0.0014 18.1 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain NLE PF08154.7 KFM07967.1 - 0.039 13.9 0.0 0.099 12.6 0.0 1.6 1 0 0 1 1 1 0 NLE (NUC135) domain Phenyl_P_gamma PF09662.5 KFM07967.1 - 0.045 13.4 0.0 0.13 11.9 0.0 1.8 1 0 0 1 1 1 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) DUF2482 PF10655.4 KFM07967.1 - 0.054 13.5 0.5 1.4 9.0 0.2 2.6 1 1 1 2 2 2 0 Hypothetical protein of unknown function (DUF2482) KN_motif PF12075.3 KFM07968.1 - 7.9e-23 79.9 0.9 1.8e-22 78.8 0.6 1.7 1 0 0 1 1 1 1 KN motif Phage_GP20 PF06810.6 KFM07968.1 - 0.044 13.2 0.5 0.079 12.4 0.3 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 Dmrt1 PF12374.3 KFM07970.1 - 5.1e-28 97.2 20.3 2e-22 79.3 4.1 3.2 3 1 0 3 3 3 2 Double-sex mab3 related transcription factor 1 Ustilago_mating PF05722.7 KFM07970.1 - 0.027 13.8 0.7 0.036 13.3 0.5 1.1 1 0 0 1 1 1 0 Ustilago B locus mating-type protein DMA PF03474.9 KFM07971.1 - 9.4e-20 70.1 0.0 1.4e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 DMRTA motif SNF2_N PF00176.18 KFM07973.1 - 2.4e-79 266.2 1.1 2.4e-79 266.2 0.7 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 KFM07973.1 - 5.7e-24 83.8 0.0 4.2e-23 81.0 0.1 2.5 2 0 0 2 2 2 1 Bromodomain SnAC PF14619.1 KFM07973.1 - 4e-18 65.3 7.0 4e-18 65.3 4.9 6.5 7 2 0 7 7 7 1 Snf2-ATP coupling, chromatin remodelling complex BRK PF07533.11 KFM07973.1 - 8.6e-18 63.5 0.0 2e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 BRK domain HSA PF07529.8 KFM07973.1 - 1.9e-17 62.7 15.5 1.9e-17 62.7 10.7 3.6 3 0 0 3 3 3 1 HSA Helicase_C PF00271.26 KFM07973.1 - 2.8e-16 59.1 0.0 5.8e-15 54.9 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain QLQ PF08880.6 KFM07973.1 - 2.7e-15 55.4 2.9 5.9e-15 54.3 2.0 1.6 1 0 0 1 1 1 1 QLQ Ldl_recept_a PF00057.13 KFM07974.1 - 2.6e-94 308.8 142.5 3.8e-13 49.0 7.7 8.5 8 0 0 8 8 8 8 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.12 KFM07974.1 - 3.1e-58 193.8 6.1 4.2e-15 55.7 0.0 5.5 5 0 0 5 5 5 5 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.1 KFM07974.1 - 7.7e-19 67.5 29.3 2.5e-09 37.0 1.4 6.0 6 1 0 6 6 6 3 Coagulation Factor Xa inhibitory site EGF_CA PF07645.10 KFM07974.1 - 5.2e-07 29.5 5.2 5.2e-07 29.5 3.6 10.9 6 3 1 7 7 7 2 Calcium-binding EGF domain SGL PF08450.7 KFM07974.1 - 6e-07 29.0 0.4 0.081 12.2 0.0 3.1 1 1 2 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region EGF PF00008.22 KFM07974.1 - 6.1e-05 22.8 20.5 0.0004 20.2 4.6 9.9 9 2 1 10 10 10 4 EGF-like domain Arylesterase PF01731.15 KFM07974.1 - 0.022 14.7 0.0 0.91 9.5 0.0 2.8 3 0 0 3 3 3 0 Arylesterase cEGF PF12662.2 KFM07974.1 - 1.1 8.9 26.1 0.23 11.1 0.5 6.5 5 0 0 5 5 5 0 Complement Clr-like EGF-like CPL PF08144.6 KFM07975.1 - 1.1e-69 232.9 0.0 1.1e-68 229.7 0.0 2.5 2 0 0 2 2 2 1 CPL (NUC119) domain PUF PF00806.14 KFM07975.1 - 0.0048 16.3 1.0 3.9 7.1 0.1 4.2 5 0 0 5 5 5 2 Pumilio-family RNA binding repeat DUF3596 PF12167.3 KFM07975.1 - 0.034 13.6 0.0 0.15 11.5 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3596) CARM1 PF11531.3 KFM07977.1 - 4.2e-20 71.5 2.0 6.4e-20 70.9 0.8 1.7 2 0 0 2 2 2 1 Coactivator-associated arginine methyltransferase 1 N terminal PRMT5 PF05185.11 KFM07977.1 - 3.3e-15 55.9 0.3 4.3e-15 55.5 0.2 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PrmA PF06325.8 KFM07977.1 - 6.2e-10 38.6 0.0 1e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 KFM07977.1 - 1.3e-09 38.6 0.0 4e-09 37.0 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFM07977.1 - 1.6e-08 34.6 0.0 3e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFM07977.1 - 2.4e-08 33.6 0.0 4.3e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFM07977.1 - 1.4e-07 31.0 0.0 9.2e-07 28.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_9 PF08003.6 KFM07977.1 - 2.2e-07 29.9 0.0 3.6e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_11 PF08241.7 KFM07977.1 - 9.7e-06 25.9 0.0 2.5e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFM07977.1 - 6.1e-05 22.7 0.0 0.00019 21.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KFM07977.1 - 0.00019 20.6 0.1 0.00029 19.9 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 KFM07977.1 - 0.00022 21.5 0.0 0.00064 20.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 KFM07977.1 - 0.0007 19.0 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 TehB PF03848.9 KFM07977.1 - 0.0023 17.1 0.1 0.0043 16.2 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_12 PF08242.7 KFM07977.1 - 0.0064 16.9 0.0 0.017 15.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 KFM07977.1 - 0.0071 15.9 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein RICTOR_M PF14666.1 KFM07977.1 - 0.027 13.4 0.1 0.045 12.7 0.1 1.3 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain RrnaAD PF00398.15 KFM07977.1 - 0.067 12.1 0.0 0.13 11.2 0.0 1.6 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.1 KFM07977.1 - 0.071 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RFX1_trans_act PF04589.8 KFM07978.1 - 6.9e-47 159.0 21.0 6.9e-47 159.0 14.5 2.6 3 0 0 3 3 3 1 RFX1 transcription activation region RFX_DNA_binding PF02257.10 KFM07978.1 - 3.7e-39 132.7 0.1 1.8e-38 130.4 0.0 2.3 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.11 KFM07978.1 - 0.045 14.0 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 Poxvirus D5 protein-like zf-C2H2 PF00096.21 KFM07979.1 - 6.9e-16 57.5 24.6 0.0017 18.5 0.7 6.0 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM07979.1 - 1.4e-13 50.3 22.7 6.7e-06 26.1 0.6 5.4 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM07979.1 - 2.3e-10 40.0 23.9 0.0071 16.6 0.1 5.7 5 0 0 5 5 5 4 C2H2-type zinc finger EpoR_lig-bind PF09067.5 KFM07979.1 - 0.098 12.6 0.2 0.21 11.6 0.2 1.5 1 0 0 1 1 1 0 Erythropoietin receptor, ligand binding zf-met PF12874.2 KFM07979.1 - 2.9 8.2 6.0 5.7 7.2 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type RNA_GG_bind PF10258.4 KFM07980.1 - 1.7e-31 107.7 3.4 2.4e-31 107.2 0.4 2.6 3 0 0 3 3 3 1 PHAX RNA-binding domain FoP_duplication PF13865.1 KFM07980.1 - 0.013 15.8 5.7 0.013 15.8 3.9 2.2 2 1 1 3 3 3 0 C-terminal duplication domain of Friend of PRMT1 Cmyb_C PF09316.5 KFM07980.1 - 0.025 14.2 0.3 0.025 14.2 0.2 1.9 2 0 0 2 2 2 0 C-myb, C-terminal Filament PF00038.16 KFM07981.1 - 5.4e-62 210.0 41.9 2.6e-61 207.8 29.0 1.9 1 1 0 1 1 1 1 Intermediate filament protein LTD PF00932.14 KFM07981.1 - 2e-21 76.2 1.5 3.2e-21 75.5 1.0 1.4 1 0 0 1 1 1 1 Lamin Tail Domain Myosin_tail_1 PF01576.14 KFM07981.1 - 0.0017 16.1 14.5 0.0017 16.1 10.0 2.5 1 1 1 2 2 2 2 Myosin tail A2M_N PF01835.14 KFM07981.1 - 0.035 14.3 0.2 0.28 11.4 0.0 2.6 2 1 1 3 3 3 0 MG2 domain AbfB PF05270.8 KFM07981.1 - 0.083 12.5 2.3 11 5.6 0.0 3.1 2 1 2 4 4 4 0 Alpha-L-arabinofuranosidase B (ABFB) Mto2_bdg PF12808.2 KFM07981.1 - 0.086 12.9 0.2 0.086 12.9 0.1 3.9 3 1 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region AAA_13 PF13166.1 KFM07981.1 - 0.56 8.5 25.7 9.7 4.5 17.7 2.1 1 1 0 1 1 1 0 AAA domain Fib_alpha PF08702.5 KFM07981.1 - 0.69 10.0 19.2 0.028 14.5 5.4 2.9 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family ATG16 PF08614.6 KFM07981.1 - 2.4 7.9 35.2 0.32 10.7 3.3 3.6 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) FlaC_arch PF05377.6 KFM07981.1 - 3.3 7.6 8.2 8 6.4 0.1 3.7 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) Reo_sigmaC PF04582.7 KFM07981.1 - 5.8 6.0 11.9 4.9 6.2 0.9 2.6 1 1 1 3 3 3 0 Reovirus sigma C capsid protein Cadherin PF00028.12 KFM07982.1 - 1.8e-113 371.0 5.0 1.1e-21 76.8 0.0 7.5 7 0 0 7 7 7 7 Cadherin domain Protocadherin PF08374.6 KFM07982.1 - 9.5e-95 316.4 2.3 1.8e-94 315.5 1.6 1.4 1 0 0 1 1 1 1 Protocadherin Cadherin_2 PF08266.7 KFM07982.1 - 1.3e-16 59.9 0.3 9.7e-09 34.6 0.0 5.0 5 0 0 5 5 5 3 Cadherin-like Y_Y_Y PF07495.8 KFM07982.1 - 0.055 13.2 0.0 1.5 8.6 0.0 3.4 3 0 0 3 3 3 0 Y_Y_Y domain He_PIG PF05345.7 KFM07982.1 - 1.8 8.6 10.2 3.4 7.7 0.1 5.0 5 1 0 5 5 5 0 Putative Ig domain Metallophos_2 PF12850.2 KFM07986.1 - 2.2e-18 66.5 0.0 2.5e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KFM07986.1 - 8.1e-06 25.3 1.1 0.0019 17.5 0.3 2.3 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase Peptidase_M10 PF00413.19 KFM07987.1 - 8.7e-55 184.6 0.0 1.3e-54 184.0 0.0 1.3 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.14 KFM07987.1 - 2.6e-43 145.5 14.8 2e-11 43.4 0.1 4.4 4 0 0 4 4 4 4 Hemopexin Peptidase_M43 PF05572.8 KFM07987.1 - 0.0017 17.9 0.1 0.003 17.1 0.1 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Astacin PF01400.19 KFM07987.1 - 0.0056 16.0 0.3 1.4 8.3 0.1 2.2 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.1 KFM07987.1 - 0.0072 16.8 0.1 0.012 16.1 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KFM07987.1 - 0.0076 16.1 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KFM07987.1 - 0.0093 15.5 0.0 0.021 14.3 0.0 1.5 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Kelch_6 PF13964.1 KFM07987.1 - 0.047 13.8 0.1 0.33 11.2 0.0 2.5 2 0 0 2 2 2 0 Kelch motif Reprolysin_2 PF13574.1 KFM07987.1 - 0.061 13.3 0.0 0.099 12.6 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like SNF5 PF04855.7 KFM07988.1 - 4.9e-65 219.3 4.6 2.8e-63 213.6 1.3 2.7 2 1 0 2 2 2 1 SNF5 / SMARCB1 / INI1 DUF1679 PF07914.6 KFM07988.1 - 0.0034 16.0 0.0 0.0053 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) DER1 PF04511.10 KFM07989.1 - 1.3e-60 204.3 13.4 1.4e-60 204.1 9.3 1.0 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.17 KFM07989.1 - 0.085 12.8 16.4 0.13 12.2 11.4 1.3 1 0 0 1 1 1 0 Rhomboid family Sugar_tr PF00083.19 KFM07990.1 - 2.2e-92 310.0 22.2 2.4e-92 309.8 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFM07990.1 - 2.1e-17 62.8 22.3 2.1e-17 62.8 15.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2085 PF09858.4 KFM07990.1 - 0.12 12.5 8.6 0.042 13.9 0.8 3.0 2 1 0 2 2 2 0 Predicted membrane protein (DUF2085) Sugar_tr PF00083.19 KFM07991.1 - 3.6e-41 141.2 6.4 1.2e-40 139.4 4.5 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFM07991.1 - 1e-13 50.7 10.3 4.4e-13 48.6 7.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KFM07991.1 - 4.6 5.5 12.0 0.41 8.9 3.3 2.3 3 0 0 3 3 3 0 MFS/sugar transport protein Sugar_tr PF00083.19 KFM07992.1 - 8.6e-32 110.2 8.9 9.6e-32 110.1 6.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFM07992.1 - 4e-16 58.6 2.5 5.1e-16 58.3 1.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KFM07992.1 - 0.00057 18.3 0.4 0.00087 17.8 0.3 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein DUF791 PF05631.9 KFM07992.1 - 0.014 14.1 1.4 0.017 13.8 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF791) BT1 PF03092.11 KFM07992.1 - 0.038 12.6 0.1 0.043 12.5 0.1 1.1 1 0 0 1 1 1 0 BT1 family Sugar_tr PF00083.19 KFM07993.1 - 3.9e-20 71.8 4.6 1.1e-19 70.4 3.2 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFM07993.1 - 0.00025 19.8 10.7 0.015 14.0 6.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFM07994.1 - 5.1e-48 163.7 3.8 6.1e-48 163.5 2.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFM07994.1 - 1.3e-18 66.8 0.3 1.8e-18 66.4 0.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KFM07994.1 - 1.4e-06 26.9 1.6 0.0025 16.2 0.6 2.1 2 0 0 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 KFM07995.1 - 1e-35 123.2 4.6 1.1e-35 123.0 3.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFM07995.1 - 6.5e-07 28.3 5.7 1e-06 27.7 4.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TM231 PF10149.4 KFM07995.1 - 3.3 6.6 8.0 0.38 9.7 2.4 1.6 2 0 0 2 2 2 0 Transmembrane protein 231 MIF PF01187.13 KFM07996.1 - 8.6e-44 148.2 0.0 9.5e-44 148.1 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.16 KFM07996.1 - 0.072 12.7 0.0 0.37 10.4 0.0 1.9 2 0 0 2 2 2 0 Tautomerase enzyme Tautomerase_2 PF14552.1 KFM07996.1 - 0.11 12.5 0.0 1.4 8.9 0.0 2.0 2 0 0 2 2 2 0 Tautomerase enzyme MIF PF01187.13 KFM07997.1 - 1.5e-37 128.2 0.0 1.6e-37 128.0 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) DEAD PF00270.24 KFM07998.1 - 4.7e-42 143.3 0.1 1.1e-41 142.1 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFM07998.1 - 4.4e-24 84.1 0.2 1.1e-23 82.8 0.1 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFM07998.1 - 7.4e-15 55.2 0.8 8.5e-14 51.7 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.9 KFM07998.1 - 0.0017 17.0 0.0 0.0031 16.1 0.0 1.4 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer SecA_DEAD PF07517.9 KFM07998.1 - 0.0021 17.3 1.8 0.0051 16.1 1.2 1.6 1 1 0 1 1 1 1 SecA DEAD-like domain SNF2_N PF00176.18 KFM07998.1 - 0.004 15.9 0.0 0.0055 15.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 KFM07998.1 - 0.012 15.7 0.1 0.89 9.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain IMS_HHH PF11798.3 KFM07998.1 - 0.047 13.7 0.1 0.16 12.1 0.0 2.0 1 0 0 1 1 1 0 IMS family HHH motif GST_C PF00043.20 KFM07999.1 - 1.3e-09 37.8 0.0 2.7e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KFM07999.1 - 3.6e-07 30.2 0.0 1e-06 28.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KFM07999.1 - 4.7e-06 26.7 0.0 1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFM07999.1 - 1.4e-05 24.9 0.1 4.1e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFM07999.1 - 8.3e-05 23.0 0.0 0.00013 22.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KFM07999.1 - 0.00064 19.6 0.0 0.0015 18.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFM08000.1 - 4.2e-09 36.2 0.0 7.3e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFM08000.1 - 5.5e-05 23.5 0.0 8.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFM08000.1 - 0.00013 21.8 0.1 0.00062 19.6 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KFM08000.1 - 0.00022 21.3 0.0 0.00047 20.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KFM08000.1 - 0.003 17.7 0.0 0.0061 16.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain MIF PF01187.13 KFM08001.1 - 3.2e-28 98.0 0.0 3.5e-28 97.9 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) MEF2_binding PF09047.5 KFM08002.1 - 2.5e-22 78.1 7.5 6.2e-22 76.9 5.2 1.8 1 0 0 1 1 1 1 MEF2 binding TPR_11 PF13414.1 KFM08002.1 - 7.4e-14 51.1 20.4 3.2e-07 29.9 0.0 7.8 7 1 1 8 8 8 3 TPR repeat TPR_2 PF07719.12 KFM08002.1 - 2.5e-09 36.3 21.5 0.18 11.8 0.1 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.23 KFM08002.1 - 2.2e-06 26.9 21.7 0.064 12.8 0.0 8.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFM08002.1 - 3.8e-05 23.5 9.1 9.9 6.6 0.0 7.7 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFM08002.1 - 9e-05 22.3 10.8 0.16 11.9 0.2 5.5 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFM08002.1 - 0.05 14.2 3.4 7.5 7.4 0.2 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFM08002.1 - 0.056 14.1 10.4 35 5.2 0.2 6.4 5 1 2 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.9 KFM08002.1 - 0.47 11.0 2.1 25 5.6 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFM08002.1 - 1 9.2 26.8 0.45 10.4 0.1 7.3 8 1 1 9 9 7 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFM08002.1 - 1.1 9.2 9.2 1.9 8.4 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat T-box PF00907.17 KFM08003.1 - 3.2e-89 297.2 0.4 4.4e-89 296.8 0.3 1.2 1 0 0 1 1 1 1 T-box SH3_2 PF07653.12 KFM08004.1 - 1e-23 82.5 0.2 4.6e-12 45.2 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH2 PF00017.19 KFM08004.1 - 2.2e-21 75.4 0.0 4.6e-21 74.4 0.0 1.6 2 0 0 2 2 2 1 SH2 domain SH3_1 PF00018.23 KFM08004.1 - 4.1e-21 74.1 0.3 4.8e-16 57.8 0.1 2.4 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 KFM08004.1 - 1.6e-18 66.0 0.1 8.6e-11 41.2 0.1 3.0 3 0 0 3 3 3 2 Variant SH3 domain Med15 PF09606.5 KFM08005.1 - 2e-246 820.0 213.7 3.2e-246 819.4 148.1 1.4 1 1 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Caldesmon PF02029.10 KFM08005.1 - 0.00025 19.6 22.7 0.00036 19.1 15.7 1.1 1 0 0 1 1 1 1 Caldesmon Herpes_UL87 PF03043.9 KFM08005.1 - 6.1 5.1 31.5 10 4.3 21.8 1.4 1 0 0 1 1 1 0 Herpesvirus UL87 family mit_SMPDase PF14724.1 KFM08006.1 - 0 1537.0 4.8 0 1536.8 3.3 1.0 1 0 0 1 1 1 1 Mitochondrial-associated sphingomyelin phosphodiesterase G_glu_transpept PF01019.16 KFM08007.1 - 3.9e-131 438.0 0.0 4.6e-131 437.8 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase G_glu_transpept PF01019.16 KFM08008.1 - 3.1e-173 576.9 0.0 3.5e-173 576.7 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase LSM PF01423.17 KFM08009.1 - 2.2e-13 49.5 0.2 3e-13 49.1 0.1 1.2 1 0 0 1 1 1 1 LSM domain Kringle PF00051.13 KFM08009.1 - 0.12 12.4 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Kringle domain Guanylate_cyc_2 PF09778.4 KFM08010.1 - 4.1e-94 313.6 7.8 4.7e-94 313.5 5.4 1.0 1 0 0 1 1 1 1 Guanylylate cyclase Peptidase_C39_2 PF13529.1 KFM08010.1 - 2.5e-11 44.1 0.0 7.3e-11 42.6 0.0 1.8 1 1 0 1 1 1 1 Peptidase_C39 like family DUF3335 PF11814.3 KFM08010.1 - 0.00021 20.5 0.2 0.21 10.7 0.1 2.3 2 0 0 2 2 2 2 Peptidase_C39 like family Peptidase_C39 PF03412.10 KFM08010.1 - 0.00034 20.4 0.1 0.0036 17.1 0.1 2.3 2 1 0 2 2 2 1 Peptidase C39 family Peptidase_C70 PF12385.3 KFM08010.1 - 0.02 14.5 0.0 0.38 10.4 0.0 2.2 2 0 0 2 2 2 0 Papain-like cysteine protease AvrRpt2 DEDD_Tnp_IS110 PF01548.12 KFM08010.1 - 0.022 14.4 0.1 0.036 13.7 0.1 1.3 1 0 0 1 1 1 0 Transposase TMEM52 PF14979.1 KFM08010.1 - 0.025 14.4 3.3 0.045 13.6 2.3 1.4 1 0 0 1 1 1 0 Transmembrane 52 Doppel PF11466.3 KFM08010.1 - 0.047 13.2 0.3 0.1 12.1 0.2 1.6 1 0 0 1 1 1 0 Prion-like protein Doppel CN_hydrolase PF00795.17 KFM08011.1 - 9.7e-40 135.8 0.1 1.3e-39 135.4 0.1 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase 7tm_1 PF00001.16 KFM08012.1 - 8.5e-53 179.1 17.7 1e-52 178.8 12.2 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM08012.1 - 1.3e-07 31.0 20.7 5.3e-07 29.0 14.4 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM08012.1 - 0.02 14.0 25.3 0.1 11.6 17.6 2.1 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx Ni_hydr_CYTB PF01292.15 KFM08012.1 - 1.8 7.9 8.9 0.034 13.5 0.8 2.0 2 1 0 2 2 2 0 Prokaryotic cytochrome b561 CH PF00307.26 KFM08013.1 - 6.8e-22 77.5 0.1 4e-21 75.0 0.1 2.5 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFM08013.1 - 1.2e-07 31.2 0.0 3.2e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 CAMSAP CH domain WEMBL PF05701.6 KFM08013.1 - 0.00071 18.1 50.5 0.00071 18.1 35.0 3.2 2 1 1 3 3 3 2 Weak chloroplast movement under blue light TPR_MLP1_2 PF07926.7 KFM08013.1 - 0.0027 17.4 12.2 0.0027 17.4 8.5 6.7 3 1 2 5 5 5 1 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.3 KFM08013.1 - 0.0082 15.9 1.7 0.0082 15.9 1.2 9.9 7 3 3 10 10 10 3 TATA element modulatory factor 1 DNA binding RhoGAP PF00620.22 KFM08014.1 - 8.4e-50 168.3 0.1 8.9e-49 165.0 0.0 2.5 2 0 0 2 2 2 1 RhoGAP domain Bcr-Abl_Oligo PF09036.5 KFM08014.1 - 1.4e-45 153.1 0.7 4.8e-45 151.4 0.5 2.1 1 0 0 1 1 1 1 Bcr-Abl oncoprotein oligomerisation domain RhoGEF PF00621.15 KFM08014.1 - 2.1e-36 125.4 0.9 4.4e-36 124.4 0.7 1.6 1 0 0 1 1 1 1 RhoGEF domain C2 PF00168.25 KFM08014.1 - 4.2e-10 39.3 0.0 1e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain PH PF00169.24 KFM08014.1 - 2.5e-08 34.0 0.3 9.2e-08 32.2 0.2 2.0 1 0 0 1 1 1 1 PH domain Ras PF00071.17 KFM08015.1 - 3.5e-45 153.2 0.3 4.5e-45 152.9 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM08015.1 - 6.5e-17 62.1 0.0 1e-16 61.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM08015.1 - 2.8e-15 56.0 0.1 3.8e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFM08015.1 - 1.3e-06 27.7 0.0 1.5e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFM08015.1 - 6.1e-06 26.1 0.0 9.2e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFM08015.1 - 0.0004 19.8 0.0 0.0095 15.3 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.1 KFM08015.1 - 0.01 15.7 0.1 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 KFM08015.1 - 0.011 15.5 0.1 0.039 13.6 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FeoB_N PF02421.13 KFM08015.1 - 0.011 15.0 0.0 0.19 11.0 0.0 2.3 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF3177 PF11375.3 KFM08015.1 - 0.035 13.5 0.0 3.8 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3177) PduV-EutP PF10662.4 KFM08015.1 - 0.046 13.1 0.0 1.2 8.6 0.0 2.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 KFM08015.1 - 0.13 12.0 0.0 0.66 9.7 0.0 2.0 2 0 0 2 2 2 0 Dynamin family G-alpha PF00503.15 KFM08016.1 - 4.2e-129 430.6 1.3 5.2e-129 430.3 0.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KFM08016.1 - 8.9e-17 60.8 0.3 6.4e-11 41.8 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFM08016.1 - 0.0006 19.0 5.7 0.023 13.8 0.3 2.6 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFM08016.1 - 0.0017 18.3 0.1 0.31 10.9 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.1 KFM08016.1 - 0.0098 15.4 0.1 0.03 13.8 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF2951 PF11166.3 KFM08016.1 - 0.0099 15.7 1.5 0.32 10.8 0.1 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2951) TniB PF05621.6 KFM08016.1 - 0.02 13.6 0.0 0.031 13.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein Miro PF08477.8 KFM08016.1 - 0.12 12.8 2.2 6.6 7.2 0.2 2.8 3 0 0 3 3 3 0 Miro-like protein HEAT_2 PF13646.1 KFM08017.1 - 8.5e-14 51.6 7.5 3.1e-10 40.2 0.3 3.2 1 1 2 3 3 3 3 HEAT repeats Arm PF00514.18 KFM08017.1 - 4.4e-13 48.5 1.9 1.9e-05 24.3 0.0 4.8 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat HEAT PF02985.17 KFM08017.1 - 5e-13 47.9 3.7 0.001 18.9 0.0 4.7 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 KFM08017.1 - 2.4e-09 37.4 4.6 0.0003 21.1 0.1 4.9 3 1 2 5 5 5 1 HEAT-like repeat Proteasom_PSMB PF10508.4 KFM08017.1 - 4.5e-07 28.5 0.6 0.00011 20.6 0.1 2.0 1 1 1 2 2 2 2 Proteasome non-ATPase 26S subunit Adaptin_N PF01602.15 KFM08017.1 - 4.7e-07 28.5 0.2 3e-06 25.8 0.1 1.9 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_PBS PF03130.11 KFM08017.1 - 0.00019 21.6 0.3 0.3 11.6 0.0 4.1 4 1 0 4 4 4 1 PBS lyase HEAT-like repeat Arm_2 PF04826.8 KFM08017.1 - 0.023 13.8 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 Armadillo-like RICTOR_N PF14664.1 KFM08017.1 - 0.025 13.2 0.4 0.62 8.5 0.0 2.0 1 1 1 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term Cnd1 PF12717.2 KFM08017.1 - 0.083 12.7 0.1 7.4 6.3 0.0 2.6 2 2 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 KFM08017.1 - 0.11 11.8 0.1 6.9 5.9 0.0 2.7 1 1 0 2 2 2 0 CLASP N terminal DUF3636 PF12331.3 KFM08017.1 - 0.13 11.8 0.2 9.1 5.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3636) SSF PF00474.12 KFM08018.1 - 2.5e-166 553.3 27.9 4.1e-166 552.6 19.4 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family Endomucin PF07010.7 KFM08018.1 - 0.13 11.5 0.0 8.5 5.6 0.0 2.3 2 0 0 2 2 2 0 Endomucin 14-3-3 PF00244.15 KFM08019.1 - 1.7e-97 325.1 8.2 1.9e-97 325.0 5.7 1.0 1 0 0 1 1 1 1 14-3-3 protein Homeobox PF00046.24 KFM08020.1 - 2.8e-09 36.4 4.8 3.2e-09 36.2 2.1 2.0 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 KFM08020.1 - 3.1e-06 26.7 0.7 7.4e-06 25.5 0.1 2.0 2 0 0 2 2 2 1 Homeobox KN domain HTH_Tnp_1 PF01527.15 KFM08020.1 - 0.033 14.1 0.9 0.067 13.1 0.1 1.9 2 1 0 2 2 2 0 Transposase CENP-B_N PF04218.8 KFM08020.1 - 0.085 12.2 0.2 0.31 10.4 0.0 2.0 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain DUF3608 PF12257.3 KFM08021.1 - 1.9e-59 200.8 0.2 2.9e-59 200.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 KFM08021.1 - 6.9e-11 41.7 0.0 1.6e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Las1 PF04031.8 KFM08021.1 - 0.011 15.3 0.0 0.027 14.1 0.0 1.6 1 0 0 1 1 1 0 Las1-like DUF3375 PF11855.3 KFM08021.1 - 0.013 14.2 0.0 0.024 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) Tantalus PF15386.1 KFM08022.1 - 3.1e-27 94.0 3.7 7.9e-27 92.8 2.6 1.7 1 0 0 1 1 1 1 Drosophila Tantalus-like Tropomodulin PF03250.9 KFM08022.1 - 0.09 12.2 0.4 0.27 10.7 0.3 1.8 1 0 0 1 1 1 0 Tropomodulin PS_Dcarbxylase PF02666.10 KFM08023.1 - 1.3e-72 243.4 0.0 1.6e-72 243.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase EIF4E-T PF10477.4 KFM08024.1 - 2.2e-170 568.2 17.0 8.8e-170 566.3 11.8 1.8 1 1 0 1 1 1 1 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF1098 PF06497.6 KFM08024.1 - 0.0077 16.2 0.0 0.024 14.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1098) Glycolytic PF00274.14 KFM08024.1 - 0.13 10.6 0.0 0.21 9.9 0.0 1.2 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-I TGS PF02824.16 KFM08025.1 - 3.8e-24 84.3 0.1 9e-24 83.0 0.0 1.7 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 KFM08025.1 - 2.1e-17 63.1 0.1 5.3e-17 61.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFM08025.1 - 7.1e-11 41.6 0.0 9.1e-10 38.0 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KFM08025.1 - 0.00075 18.9 0.1 0.57 9.5 0.0 3.6 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KFM08025.1 - 0.0013 18.6 0.4 1.7 8.4 0.0 2.3 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 KFM08025.1 - 0.0038 16.0 0.2 0.023 13.5 0.0 2.0 2 0 0 2 2 2 1 ArgK protein Miro PF08477.8 KFM08025.1 - 0.021 15.3 0.0 0.066 13.7 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein AAA_28 PF13521.1 KFM08025.1 - 0.1 12.5 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain zf-C2H2_4 PF13894.1 KFM08026.1 - 5.1e-35 117.2 44.6 2.7e-05 24.1 0.0 8.6 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2 PF00096.21 KFM08026.1 - 2.5e-31 106.1 46.4 4.9e-05 23.4 0.6 8.6 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM08026.1 - 6.6e-19 67.1 58.2 7.6e-07 29.1 1.5 10.3 11 0 0 11 11 10 4 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFM08026.1 - 3.9e-14 52.2 30.4 0.0014 18.7 0.4 8.3 7 1 1 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM08026.1 - 2e-11 43.6 30.0 0.031 14.4 0.4 8.1 8 0 0 8 8 8 5 Zinc-finger of C2H2 type BTB PF00651.26 KFM08026.1 - 1.5e-08 34.6 0.0 2.5e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-Di19 PF05605.7 KFM08026.1 - 0.00021 21.3 29.7 0.17 12.0 0.9 5.9 4 2 2 6 6 6 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 KFM08026.1 - 0.006 16.4 37.7 0.021 14.7 0.9 8.0 8 0 0 8 8 8 2 C2H2-type zinc finger ROS_MUCR PF05443.6 KFM08026.1 - 0.025 14.3 1.1 4.3 7.1 0.0 2.9 2 1 0 2 2 2 0 ROS/MUCR transcriptional regulator protein zf-C2H2_2 PF12756.2 KFM08026.1 - 0.069 13.2 27.2 35 4.5 1.5 7.3 3 1 4 7 7 7 0 C2H2 type zinc-finger (2 copies) XPA_N PF01286.13 KFM08026.1 - 0.11 12.1 0.0 0.11 12.1 0.0 6.3 8 0 0 8 8 7 0 XPA protein N-terminal ARS2 PF04959.8 KFM08026.1 - 0.4 10.8 4.3 2 8.5 0.1 3.2 2 1 1 3 3 3 0 Arsenite-resistance protein 2 DUF629 PF04780.7 KFM08026.1 - 0.75 8.2 8.5 1.6 7.1 0.7 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF629) GAGA PF09237.6 KFM08026.1 - 0.98 9.0 22.3 4.6 6.8 0.3 6.1 6 1 1 7 7 7 0 GAGA factor DUF2225 PF09986.4 KFM08026.1 - 3.9 6.8 5.7 4.4 6.7 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-RING_3 PF14369.1 KFM08026.1 - 7.1 6.7 17.8 4.9 7.2 0.1 5.6 6 0 0 6 6 6 0 zinc-finger Zn_ribbon_2 PF12674.2 KFM08026.1 - 8.1 6.8 13.1 6.6 7.1 0.2 4.0 5 1 1 6 6 5 0 Putative zinc ribbon domain AT_hook PF02178.14 KFM08026.1 - 9.9 6.2 13.5 0.076 12.7 2.8 2.3 2 0 0 2 2 2 0 AT hook motif Kringle PF00051.13 KFM08027.1 - 0.00013 22.0 0.4 0.00025 21.0 0.3 1.5 1 0 0 1 1 1 1 Kringle domain TMEM154 PF15102.1 KFM08027.1 - 0.043 13.5 0.0 0.056 13.1 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family SDF PF00375.13 KFM08027.1 - 0.06 12.0 0.0 0.07 11.8 0.0 1.1 1 0 0 1 1 1 0 Sodium:dicarboxylate symporter family SUR7 PF06687.7 KFM08027.1 - 0.084 12.4 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 SUR7/PalI family Pkinase_Tyr PF07714.12 KFM08028.1 - 5.1e-51 173.2 0.0 1.1e-50 172.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM08028.1 - 4.6e-49 166.9 0.0 7.1e-49 166.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LIM PF00412.17 KFM08028.1 - 1.7e-26 92.0 18.8 1.1e-16 60.5 3.5 2.6 2 0 0 2 2 2 2 LIM domain PDZ PF00595.19 KFM08028.1 - 2.3e-15 56.4 0.0 4.1e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Kdo PF06293.9 KFM08028.1 - 0.00026 20.0 0.0 0.00046 19.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFM08028.1 - 0.0071 16.1 0.1 0.024 14.3 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family PDZ_2 PF13180.1 KFM08028.1 - 0.051 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 PDZ domain RRN7 PF11781.3 KFM08028.1 - 0.6 9.6 10.2 0.18 11.3 2.1 2.6 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C3HC4_2 PF13923.1 KFM08029.1 - 1.5e-10 40.9 9.0 2e-10 40.5 6.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM08029.1 - 1.5e-10 40.5 7.5 2.1e-10 40.0 5.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM08029.1 - 2.6e-10 39.7 5.1 3.7e-10 39.2 3.5 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM08029.1 - 1.4e-09 37.6 9.4 1.9e-09 37.1 6.5 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KFM08029.1 - 1.1e-07 31.4 6.5 1.6e-07 30.9 4.5 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KFM08029.1 - 5.6e-06 25.9 4.8 4.4e-05 23.0 1.3 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 KFM08029.1 - 4.5e-05 23.2 2.1 6.6e-05 22.6 1.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 KFM08029.1 - 0.00011 22.0 7.7 0.00016 21.4 5.3 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KFM08029.1 - 0.00011 22.1 5.4 0.0002 21.3 3.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger Baculo_IE-1 PF05290.6 KFM08029.1 - 0.00047 19.8 2.6 0.00072 19.3 1.8 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Rtf2 PF04641.7 KFM08029.1 - 0.0086 15.2 0.1 0.011 14.9 0.1 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_4 PF14570.1 KFM08029.1 - 0.018 14.5 5.4 0.038 13.5 3.8 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.1 KFM08029.1 - 0.047 13.4 1.5 0.099 12.4 0.9 1.8 1 1 0 1 1 1 0 Zinc-binding RING-finger Prok-RING_4 PF14447.1 KFM08029.1 - 0.075 12.5 4.8 0.35 10.4 3.3 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 TerY-C PF15616.1 KFM08029.1 - 0.69 9.8 3.6 0.99 9.3 2.5 1.2 1 0 0 1 1 1 0 TerY-C metal binding domain IBR PF01485.16 KFM08029.1 - 2 8.3 9.0 32 4.5 0.1 2.4 1 1 1 2 2 2 0 IBR domain DUF1272 PF06906.6 KFM08029.1 - 2.6 7.9 5.9 13 5.7 4.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) HNF-1B_C PF04812.8 KFM08031.1 - 4e-100 334.1 29.1 6.7e-100 333.4 20.2 1.4 1 0 0 1 1 1 1 Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus HNF-1_N PF04814.8 KFM08031.1 - 1.2e-85 286.1 2.7 1.2e-85 286.1 1.9 1.8 2 0 0 2 2 2 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus Homeobox PF00046.24 KFM08031.1 - 1.1e-06 28.2 0.9 6.5e-06 25.6 0.2 2.7 1 1 1 2 2 2 1 Homeobox domain DUF2183 PF09949.4 KFM08031.1 - 0.11 12.4 0.1 0.29 11.1 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) Peptidase_A22B PF04258.8 KFM08032.1 - 1.5e-96 323.3 10.7 1.9e-96 323.0 7.4 1.1 1 0 0 1 1 1 1 Signal peptide peptidase Acyl-CoA_dh_1 PF00441.19 KFM08033.1 - 6.7e-52 175.5 8.6 1.2e-51 174.7 5.9 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KFM08033.1 - 1.6e-36 125.2 0.5 6.6e-36 123.3 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KFM08033.1 - 5.4e-24 84.9 5.6 9.4e-24 84.1 3.9 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KFM08033.1 - 3.4e-18 64.8 1.9 6.3e-18 64.0 1.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain HATPase_c_3 PF13589.1 KFM08033.1 - 0.12 12.0 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GMP_PDE_delta PF05351.6 KFM08034.1 - 7.5e-79 263.0 1.7 8.6e-79 262.8 1.2 1.0 1 0 0 1 1 1 1 GMP-PDE, delta subunit Malectin PF11721.3 KFM08035.1 - 2.5e-36 125.0 0.2 2.5e-36 125.0 0.1 1.5 2 0 0 2 2 2 1 Di-glucose binding within endoplasmic reticulum EF-hand_1 PF00036.27 KFM08036.1 - 3.5e-31 104.1 15.4 2.4e-10 38.9 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 KFM08036.1 - 2.3e-25 86.1 6.1 5.7e-09 35.1 0.0 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 KFM08036.1 - 2.3e-24 85.3 8.1 6.9e-16 58.1 0.9 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KFM08036.1 - 2.6e-21 74.9 13.0 1.9e-13 49.8 0.4 3.7 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 KFM08036.1 - 2.9e-21 73.7 12.5 2e-08 33.2 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 KFM08036.1 - 4.5e-09 36.1 0.1 0.0029 17.4 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 KFM08036.1 - 2.6e-05 24.1 0.9 0.0021 18.0 0.0 2.3 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.8 KFM08036.1 - 0.0013 18.4 0.3 1 9.1 0.0 2.5 2 1 0 2 2 2 2 Tellurite resistance protein TerB EF-hand_4 PF12763.2 KFM08036.1 - 0.002 17.8 1.3 0.042 13.5 0.1 2.5 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand POTRA_2 PF08479.6 KFM08036.1 - 0.0046 16.5 0.0 0.012 15.2 0.0 1.8 1 0 0 1 1 1 1 POTRA domain, ShlB-type DUF4375 PF14300.1 KFM08036.1 - 0.072 13.0 0.3 0.79 9.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) FliG_N PF14842.1 KFM08036.1 - 0.1 12.7 0.2 0.95 9.5 0.0 2.3 3 0 0 3 3 3 0 FliG N-terminal domain Dockerin_1 PF00404.13 KFM08036.1 - 0.16 11.7 9.8 1.8 8.4 0.9 3.5 3 0 0 3 3 3 0 Dockerin type I repeat EFhand_Ca_insen PF08726.5 KFM08036.1 - 0.34 10.9 1.4 3.5 7.6 0.1 2.7 2 2 0 2 2 2 0 Ca2+ insensitive EF hand RNase_P_Rpp14 PF01900.14 KFM08037.1 - 7.7e-28 96.5 0.0 1.1e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family SPATA25 PF15218.1 KFM08037.1 - 0.043 13.2 0.0 0.053 12.9 0.0 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 25 Ras PF00071.17 KFM08038.1 - 8.4e-61 204.0 0.2 1e-60 203.8 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM08038.1 - 3.2e-20 72.8 0.0 5e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM08038.1 - 1.9e-12 46.7 0.0 2.2e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFM08038.1 - 1.1e-05 24.6 0.0 1.4e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFM08038.1 - 1.8e-05 24.2 0.0 4.3e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFM08038.1 - 0.00011 22.1 0.0 0.00016 21.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KFM08038.1 - 0.051 12.7 0.1 0.12 11.5 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Beta-Casp PF10996.3 KFM08038.1 - 0.069 13.0 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Beta-Casp domain AAA_22 PF13401.1 KFM08038.1 - 0.12 12.4 0.0 0.71 10.0 0.0 1.9 1 1 1 2 2 2 0 AAA domain Peptidase_M24 PF00557.19 KFM08039.1 - 1.5e-26 93.2 0.1 1.8e-26 93.0 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 NADPH_Ox PF08414.5 KFM08039.1 - 0.097 12.7 0.0 0.8 9.8 0.0 2.2 2 0 0 2 2 2 0 Respiratory burst NADPH oxidase zf-CCCH PF00642.19 KFM08040.1 - 5.7e-09 35.4 14.9 1.5e-07 30.9 0.3 3.3 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MbeD_MobD PF04899.7 KFM08040.1 - 0.015 15.2 0.2 0.071 13.0 0.0 2.1 2 0 0 2 2 2 0 MbeD/MobD like bZIP_1 PF00170.16 KFM08040.1 - 0.071 13.0 1.5 0.17 11.8 1.0 1.6 1 0 0 1 1 1 0 bZIP transcription factor DUF904 PF06005.7 KFM08040.1 - 0.091 13.0 4.7 0.16 12.2 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) bZIP_2 PF07716.10 KFM08040.1 - 0.31 10.8 4.8 0.46 10.3 2.6 1.9 1 1 0 1 1 1 0 Basic region leucine zipper zf-CCCH_2 PF14608.1 KFM08040.1 - 1.7 8.7 13.7 1.5 8.9 1.2 3.2 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type USP8_interact PF08941.5 KFM08041.1 - 2.3e-20 72.6 3.8 2.3e-20 72.6 2.6 1.6 2 0 0 2 2 2 1 USP8 interacting Sina PF03145.11 KFM08041.1 - 9e-07 28.7 1.8 1.3e-06 28.2 1.3 1.3 1 0 0 1 1 1 1 Seven in absentia protein family zf-RING_2 PF13639.1 KFM08041.1 - 6.5e-06 25.8 4.2 6.5e-06 25.8 2.9 2.1 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4 PF00097.20 KFM08041.1 - 2.1e-05 24.0 3.7 2.1e-05 24.0 2.6 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM08041.1 - 3.7e-05 23.6 2.5 3.7e-05 23.6 1.7 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFM08041.1 - 3.9e-05 23.6 5.0 3.9e-05 23.6 3.5 2.3 2 1 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KFM08041.1 - 0.00012 21.7 1.4 0.00012 21.7 1.0 2.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM08041.1 - 0.00025 20.7 3.3 0.00025 20.7 2.3 2.3 3 0 0 3 3 3 1 zinc-RING finger domain zf-TRAF PF02176.13 KFM08041.1 - 0.0011 19.3 7.7 0.035 14.4 1.4 2.8 1 1 1 2 2 2 2 TRAF-type zinc finger zf-Apc11 PF12861.2 KFM08041.1 - 0.0052 16.5 2.2 0.013 15.2 1.5 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 KFM08041.1 - 0.033 13.9 0.2 0.033 13.9 0.1 1.9 2 1 0 2 2 2 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 KFM08041.1 - 0.033 14.0 3.1 0.033 14.0 2.1 2.4 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING SlyX PF04102.7 KFM08041.1 - 0.05 13.9 5.0 0.15 12.4 3.5 1.8 1 1 0 1 1 1 0 SlyX Adeno_E4_34 PF04528.8 KFM08041.1 - 0.063 12.8 1.3 0.11 12.0 0.9 1.4 1 0 0 1 1 1 0 Adenovirus early E4 34 kDa protein conserved region IncA PF04156.9 KFM08041.1 - 0.067 12.7 1.8 0.093 12.3 1.2 1.2 1 0 0 1 1 1 0 IncA protein Baculo_RING PF05883.6 KFM08041.1 - 0.08 12.7 0.6 0.36 10.6 0.1 2.1 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain DUF1754 PF08555.5 KFM08041.1 - 0.1 13.2 0.4 0.14 12.7 0.3 1.2 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) DUF1664 PF07889.7 KFM08041.1 - 0.14 11.9 1.1 0.24 11.1 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Atx10homo_assoc PF09759.4 KFM08041.1 - 0.15 11.7 2.0 0.2 11.4 0.3 1.8 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain Atg14 PF10186.4 KFM08041.1 - 0.81 8.5 7.6 0.99 8.2 5.3 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Ank_2 PF12796.2 KFM08042.1 - 5.1e-238 770.3 102.2 5.4e-22 77.9 0.1 14.2 1 1 16 17 17 17 17 Ankyrin repeats (3 copies) Ank PF00023.25 KFM08042.1 - 4.6e-178 568.9 77.5 2.2e-08 33.5 0.3 28.2 28 0 0 28 28 28 27 Ankyrin repeat Ank_4 PF13637.1 KFM08042.1 - 3.1e-156 505.3 50.7 1.7e-11 44.3 0.3 19.7 8 3 13 21 21 21 21 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM08042.1 - 6.8e-134 432.9 65.6 1.6e-11 44.0 0.0 22.4 5 5 16 23 23 23 23 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM08042.1 - 1.8e-127 402.2 64.1 2.3e-06 27.2 0.1 27.9 28 0 0 28 28 28 26 Ankyrin repeat Polyketide_cyc PF03364.15 KFM08043.1 - 1.2e-26 93.1 0.2 1.5e-26 92.9 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 KFM08043.1 - 3.4e-05 24.0 0.0 4.2e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Citrate_synt PF00285.16 KFM08044.1 - 1.2e-104 349.8 0.0 1.4e-104 349.6 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase DUF3456 PF11938.3 KFM08045.1 - 3.8e-44 150.3 0.7 4.3e-44 150.1 0.5 1.0 1 0 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP SapB_2 PF03489.12 KFM08045.1 - 0.015 15.2 0.2 0.074 13.1 0.0 2.2 3 0 0 3 3 3 0 Saposin-like type B, region 2 UCH_1 PF13423.1 KFM08046.1 - 7.1e-68 229.1 0.0 9.3e-68 228.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.24 KFM08046.1 - 1.8e-08 33.8 1.5 2.8e-07 29.9 1.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 KFM08046.1 - 2.8e-05 24.4 0.0 7.2e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Exonuclease Cadherin PF00028.12 KFM08048.1 - 3.2e-14 52.9 0.0 1.9e-10 40.8 0.0 2.3 2 1 0 2 2 2 2 Cadherin domain zf-C2H2_jaz PF12171.3 KFM08049.1 - 6.3e-07 29.3 1.2 1.4e-06 28.2 0.8 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM08049.1 - 2.5e-06 27.4 1.3 4e-06 26.8 0.9 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.7 KFM08049.1 - 0.00013 21.4 1.0 0.00022 20.7 0.7 1.4 1 0 0 1 1 1 1 U1 zinc finger DUF1777 PF08648.7 KFM08049.1 - 0.003 17.3 12.1 0.003 17.3 8.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) Cgr1 PF03879.9 KFM08049.1 - 0.0057 16.8 18.0 0.0057 16.8 12.5 2.3 2 0 0 2 2 2 1 Cgr1 family CCDC84 PF14968.1 KFM08049.1 - 0.12 11.8 12.4 0.03 13.8 4.9 1.9 1 1 1 2 2 2 0 Coiled coil protein 84 CAF-1_p150 PF11600.3 KFM08049.1 - 0.99 8.7 31.9 0.018 14.4 12.7 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF87 PF01935.12 KFM08049.1 - 1.9 8.2 6.2 2.4 7.9 4.3 1.3 1 1 0 1 1 1 0 Domain of unknown function DUF87 DUF3959 PF13105.1 KFM08049.1 - 4.2 6.6 6.3 6.7 5.9 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Caldesmon PF02029.10 KFM08049.1 - 5.9 5.1 25.6 0.21 9.9 11.7 1.9 2 0 0 2 2 2 0 Caldesmon tRNA-synt_His PF13393.1 KFM08050.1 - 1.4e-33 116.3 0.0 1.9e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.15 KFM08050.1 - 1.6e-13 50.3 0.0 3.1e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.20 KFM08050.1 - 3e-13 49.7 0.0 4.7e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon2 PF12745.2 KFM08050.1 - 0.0094 15.1 0.0 0.012 14.7 0.0 1.1 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2d PF01409.15 KFM08050.1 - 0.063 12.4 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 KFM08050.1 - 0.12 11.1 0.0 1.7 7.3 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) tRNA-synt_His PF13393.1 KFM08051.1 - 2.4e-43 148.4 0.0 4.3e-43 147.5 0.0 1.4 2 0 0 2 2 2 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 KFM08051.1 - 1.8e-19 69.9 0.0 3.3e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KFM08051.1 - 1.8e-16 59.8 1.1 3.6e-16 58.8 0.7 1.5 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.2 KFM08051.1 - 1.6e-06 27.4 0.4 2.3e-06 26.9 0.3 1.2 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.15 KFM08051.1 - 0.00026 19.8 0.0 0.0039 16.0 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) WHEP-TRS PF00458.15 KFM08051.1 - 0.014 15.0 0.4 0.038 13.6 0.3 1.8 1 0 0 1 1 1 0 WHEP-TRS domain tRNA-synt_2d PF01409.15 KFM08051.1 - 0.033 13.3 0.0 0.066 12.3 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) RRM_1 PF00076.17 KFM08052.1 - 4.2e-07 29.5 0.0 5.8e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM08052.1 - 0.0015 18.4 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 KFM08053.1 - 2.2e-19 68.5 0.0 0.0001 22.0 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KFM08053.1 - 0.0031 16.3 0.0 0.06 12.0 0.0 2.1 2 0 0 2 2 2 1 Nup133 N terminal like BBS2_Mid PF14783.1 KFM08053.1 - 0.0083 15.8 0.0 0.04 13.6 0.0 2.1 1 1 1 2 2 2 1 Ciliary BBSome complex subunit 2, middle region L51_S25_CI-B8 PF05047.11 KFM08054.1 - 2.5e-18 65.5 0.0 2.9e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain LRR_4 PF12799.2 KFM08055.1 - 2.1e-16 59.1 13.3 0.00033 20.1 0.7 5.0 2 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM08055.1 - 2.2e-15 56.1 14.0 2.3e-07 30.4 2.3 4.8 2 2 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 KFM08055.1 - 5.3e-12 44.0 16.9 0.53 10.5 0.0 8.4 6 1 2 8 8 8 5 Leucine Rich Repeat LRR_7 PF13504.1 KFM08055.1 - 3.5e-09 35.3 14.2 1.3 9.5 0.0 8.5 8 0 0 8 8 8 3 Leucine rich repeat LRR_6 PF13516.1 KFM08055.1 - 2.1e-06 27.2 20.0 1.6 9.0 0.1 7.8 6 2 2 8 8 8 3 Leucine Rich repeat LRRCT PF01463.19 KFM08055.1 - 0.042 14.1 1.4 0.44 10.9 0.4 3.3 2 0 0 2 2 2 0 Leucine rich repeat C-terminal domain Lamprin PF06403.6 KFM08056.1 - 0.1 12.3 2.4 0.1 12.3 1.7 1.1 1 0 0 1 1 1 0 Lamprin Nuc_sug_transp PF04142.10 KFM08057.1 - 5.8e-42 143.4 15.7 8.2e-42 142.9 10.8 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 KFM08057.1 - 0.0016 18.4 8.8 0.0016 18.4 6.1 2.9 2 1 1 3 3 3 1 EamA-like transporter family EmrE PF13536.1 KFM08057.1 - 5.4 7.2 31.7 0.023 14.8 4.0 3.5 2 2 1 3 3 3 0 Multidrug resistance efflux transporter RVT_1 PF00078.22 KFM08058.1 - 0.0015 17.9 0.0 0.0026 17.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TMEM173 PF15009.1 KFM08059.1 - 1.6e-95 319.4 0.4 2e-95 319.1 0.3 1.1 1 0 0 1 1 1 1 Transmembrane protein 173 UQ_con PF00179.21 KFM08060.1 - 1.8e-51 173.2 0.0 2e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFM08060.1 - 0.00019 21.2 0.0 0.00021 21.0 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KFM08060.1 - 0.0024 17.7 0.0 0.0034 17.2 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KFM08060.1 - 0.043 13.5 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain zf-CXXC PF02008.15 KFM08061.1 - 1.4e-07 31.1 23.5 2.3e-07 30.5 16.3 1.3 1 0 0 1 1 1 1 CXXC zinc finger domain YlbD_coat PF14071.1 KFM08061.1 - 0.087 12.8 0.2 0.14 12.1 0.2 1.3 1 0 0 1 1 1 0 Putative coat protein QueC PF06508.8 KFM08061.1 - 3.5 6.8 11.3 2.1 7.5 0.6 2.3 1 1 1 2 2 2 0 Queuosine biosynthesis protein QueC Sec7 PF01369.15 KFM08063.1 - 6.5e-51 172.6 0.1 6.5e-51 172.6 0.1 1.6 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.1 KFM08063.1 - 9.5e-38 129.0 3.4 1.2e-37 128.7 0.1 2.5 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.24 KFM08063.1 - 4.3e-12 46.1 0.1 1.2e-11 44.7 0.1 1.8 1 0 0 1 1 1 1 PH domain Neuregulin PF02158.10 KFM08064.1 - 5.1e-99 331.8 19.0 7.4e-99 331.2 13.2 1.2 1 0 0 1 1 1 1 Neuregulin family I-set PF07679.11 KFM08064.1 - 9.6e-20 70.2 0.0 2.1e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM08064.1 - 1.6e-13 50.5 0.3 1.4e-12 47.4 0.0 2.7 3 0 0 3 3 3 1 Immunoglobulin domain ig PF00047.20 KFM08064.1 - 7.9e-13 48.3 0.0 2.1e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFM08064.1 - 4.6e-08 33.4 0.0 2.7e-07 31.0 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.12 KFM08064.1 - 3.6e-06 26.8 0.5 1.9e-05 24.5 0.0 2.5 2 1 0 2 2 2 1 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM08064.1 - 0.001 18.9 0.0 0.0033 17.3 0.0 1.9 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain hEGF PF12661.2 KFM08064.1 - 0.047 13.7 3.3 0.14 12.3 2.3 1.9 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_2 PF07974.8 KFM08064.1 - 0.99 9.6 9.5 5.1 7.3 6.6 2.3 1 0 0 1 1 1 0 EGF-like domain EGF PF00008.22 KFM08064.1 - 1.2 9.2 10.5 0.5 10.3 4.8 2.4 2 0 0 2 2 2 0 EGF-like domain PurA PF04845.8 KFM08065.1 - 1.5e-111 370.7 0.0 1.7e-111 370.5 0.0 1.0 1 0 0 1 1 1 1 PurA ssDNA and RNA-binding protein DUF3276 PF11680.3 KFM08065.1 - 2e-06 27.5 3.7 0.11 12.2 0.0 3.2 2 1 0 3 3 3 3 Protein of unknown function (DUF3276) Aminotran_1_2 PF00155.16 KFM08065.1 - 0.07 12.0 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Prefoldin_2 PF01920.15 KFM08067.1 - 4.1e-14 52.2 7.6 4.5e-14 52.0 5.2 1.0 1 0 0 1 1 1 1 Prefoldin subunit Lant_dehyd_C PF04738.8 KFM08067.1 - 0.021 13.0 0.1 0.021 13.0 0.1 1.1 1 0 0 1 1 1 0 Lantibiotic dehydratase, C terminus EGF PF00008.22 KFM08068.1 - 1.3e-05 25.0 5.2 2.8e-05 23.9 3.6 1.6 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.2 KFM08068.1 - 0.00046 20.0 3.0 0.0011 18.9 2.1 1.7 1 0 0 1 1 1 1 Human growth factor-like EGF CD34_antigen PF06365.7 KFM08068.1 - 0.043 13.4 0.0 0.058 13.0 0.0 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family AP_endonuc_2 PF01261.19 KFM08068.1 - 0.072 12.3 0.0 0.087 12.0 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel HCO3_cotransp PF00955.16 KFM08069.1 - 1e-220 733.7 1.7 1.3e-220 733.4 1.2 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.8 KFM08069.1 - 1.3e-64 218.2 0.6 1.3e-47 162.5 0.0 3.2 2 1 0 3 3 3 3 Band 3 cytoplasmic domain Ank_2 PF12796.2 KFM08070.1 - 1.2e-191 621.7 64.5 4.5e-25 87.7 0.9 12.3 3 3 7 12 12 12 12 Ankyrin repeats (3 copies) Ank PF00023.25 KFM08070.1 - 1.9e-176 563.8 61.5 1.5e-10 40.2 0.0 25.5 25 0 0 25 25 25 24 Ankyrin repeat Ank_4 PF13637.1 KFM08070.1 - 1.7e-136 442.4 18.9 1.4e-11 44.5 0.0 14.7 9 4 3 14 14 14 14 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM08070.1 - 5.6e-119 375.9 36.3 1.4e-05 24.8 0.0 25.5 25 0 0 25 25 25 24 Ankyrin repeat Ank_5 PF13857.1 KFM08070.1 - 7.4e-109 353.3 51.5 5.7e-09 35.9 0.0 23.9 2 2 23 25 25 25 25 Ankyrin repeats (many copies) KH_1 PF00013.24 KFM08070.1 - 2e-14 52.9 0.9 4.8e-14 51.7 0.6 1.7 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 KFM08070.1 - 4.2e-10 39.0 2.0 1.3e-09 37.4 1.4 2.0 1 0 0 1 1 1 1 KH domain Plasmodium_Vir PF05795.6 KFM08070.1 - 0.9 8.6 19.9 0.036 13.2 9.4 1.9 2 0 0 2 2 2 0 Plasmodium vivax Vir protein eIF_4EBP PF05456.6 KFM08071.1 - 3.2e-17 62.2 0.1 3.4e-17 62.2 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) SRA1 PF07304.6 KFM08072.1 - 7.3e-45 152.5 0.5 8e-45 152.3 0.3 1.0 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) RESP18 PF14948.1 KFM08072.1 - 0.072 13.1 0.1 0.076 13.0 0.1 1.2 1 0 0 1 1 1 0 RESP18 domain GUN4 PF05419.7 KFM08072.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 GUN4-like PID PF00640.18 KFM08073.1 - 5.1e-48 162.6 0.0 7.2e-28 97.3 0.0 2.1 2 0 0 2 2 2 2 Phosphotyrosine interaction domain (PTB/PID) WW PF00397.21 KFM08073.1 - 7.7e-06 25.6 4.8 1.6e-05 24.6 3.3 1.6 1 0 0 1 1 1 1 WW domain PTB PF08416.8 KFM08073.1 - 0.00068 19.5 0.0 0.002 18.0 0.0 1.7 2 0 0 2 2 2 1 Phosphotyrosine-binding domain Syncollin PF15138.1 KFM08074.1 - 3.9e-43 145.8 0.7 1.2e-28 99.1 0.1 2.0 1 1 1 2 2 2 2 Syncollin Crystall_3 PF08964.5 KFM08074.1 - 0.00016 21.2 0.0 0.051 13.2 0.0 2.4 1 1 1 2 2 2 2 Beta/Gamma crystallin ubiquitin PF00240.18 KFM08075.1 - 4.3e-15 54.8 0.0 4.6e-15 54.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.1 KFM08075.1 - 0.014 15.2 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like RVT_1 PF00078.22 KFM08076.1 - 4e-17 62.3 0.0 4.9e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SIN1 PF05422.7 KFM08077.1 - 1.6e-172 574.7 1.9 1.9e-172 574.4 1.3 1.1 1 0 0 1 1 1 1 Stress-activated map kinase interacting protein 1 (SIN1) DUF2464 PF10240.4 KFM08078.1 - 3.9e-90 301.5 0.0 4.5e-90 301.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2464) Homeobox PF00046.24 KFM08079.1 - 4.5e-18 64.6 2.3 9.8e-18 63.5 1.6 1.6 1 0 0 1 1 1 1 Homeobox domain LIM PF00412.17 KFM08079.1 - 6.8e-17 61.2 11.3 1.1e-16 60.6 7.8 1.4 1 0 0 1 1 1 1 LIM domain Homeobox_KN PF05920.6 KFM08079.1 - 8.3e-05 22.2 0.0 0.00019 21.0 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain DUF1510 PF07423.6 KFM08079.1 - 0.071 12.4 1.1 0.11 11.8 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Pax7 PF12360.3 KFM08079.1 - 0.1 12.8 0.7 5 7.4 0.0 2.6 2 0 0 2 2 2 0 Paired box protein 7 YlqD PF11068.3 KFM08079.1 - 0.12 12.3 4.0 0.21 11.6 2.8 1.3 1 0 0 1 1 1 0 YlqD protein BTB PF00651.26 KFM08080.1 - 3.6e-26 91.3 0.0 6.3e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 KFM08080.1 - 8.6e-11 41.5 16.4 7.1e-07 29.2 0.4 4.1 4 0 0 4 4 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFM08080.1 - 8.6e-10 38.3 24.2 0.00029 20.9 1.5 4.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM08080.1 - 2.9e-07 30.3 16.2 0.034 14.4 0.8 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM08080.1 - 0.19 11.6 12.1 0.95 9.4 0.1 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM08080.1 - 0.3 11.2 14.7 5 7.3 0.2 3.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM08080.1 - 0.36 11.0 13.6 2.1 8.7 0.5 4.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type XPA_N PF01286.13 KFM08080.1 - 0.68 9.6 0.0 0.68 9.6 0.0 2.7 3 0 0 3 3 3 0 XPA protein N-terminal DUF968 PF06147.6 KFM08080.1 - 1.2 8.9 7.9 2.2 8.1 5.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF968) DUF2256 PF10013.4 KFM08080.1 - 3.8 7.3 8.2 0.36 10.6 0.4 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-CSL PF05207.8 KFM08080.1 - 6.1 6.4 7.1 1.9e+02 1.6 4.7 3.1 1 1 1 2 2 2 0 CSL zinc finger BTB PF00651.26 KFM08081.1 - 2.3e-26 91.9 0.2 3.9e-26 91.2 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.21 KFM08081.1 - 5.7e-17 60.9 17.0 2.9e-05 24.1 1.5 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM08081.1 - 2e-13 49.8 16.2 5.1e-07 29.6 0.4 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM08081.1 - 1.2e-12 47.2 12.7 0.00032 20.8 0.3 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 KFM08081.1 - 3.1e-08 33.5 8.3 0.0047 17.0 0.1 4.0 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFM08081.1 - 5.6e-07 29.5 7.0 0.025 14.7 0.3 3.9 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding DUF3342 PF11822.3 KFM08081.1 - 1.4e-05 24.4 0.1 1.4e-05 24.4 0.1 2.2 2 1 1 3 3 3 1 Domain of unknown function (DUF3342) zf-BED PF02892.10 KFM08081.1 - 2.4e-05 23.9 15.3 0.069 12.9 0.4 3.5 2 1 1 3 3 3 3 BED zinc finger zf-C2H2_2 PF12756.2 KFM08081.1 - 0.023 14.7 10.9 0.11 12.5 0.0 3.9 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) BIR PF00653.16 KFM08081.1 - 0.19 12.1 1.7 0.24 11.8 0.1 2.0 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain DUF4187 PF13821.1 KFM08081.1 - 0.37 10.4 2.8 6.3 6.4 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4187) zf-Di19 PF05605.7 KFM08081.1 - 0.51 10.5 8.6 1.8 8.7 2.7 3.2 3 1 0 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 KFM08081.1 - 0.82 9.4 11.3 4.2 7.1 0.1 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type C1_1 PF00130.17 KFM08081.1 - 3.3 7.5 7.2 5.4 6.8 0.6 2.8 3 0 0 3 3 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PyrI_C PF02748.10 KFM08081.1 - 3.8 7.0 8.4 7.6 6.0 0.1 3.5 2 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-trcl PF13451.1 KFM08081.1 - 4.1 7.1 7.7 3.6 7.2 3.0 2.3 2 0 0 2 2 2 0 Probable zinc-binding domain RasGEF PF00617.14 KFM08082.1 - 3.9e-51 173.4 1.0 6.8e-51 172.6 0.6 1.5 1 1 0 1 1 1 1 RasGEF domain PH PF00169.24 KFM08082.1 - 1.9e-07 31.1 0.0 4.4e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 PH domain Fibrinogen_C PF00147.13 KFM08083.1 - 9.9e-77 257.6 12.0 1.4e-76 257.2 8.3 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Fer4_NifH PF00142.13 KFM08083.1 - 0.012 14.7 2.2 0.017 14.2 1.2 1.5 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF2115 PF09888.4 KFM08083.1 - 0.014 15.5 4.7 0.014 15.5 3.3 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) WD40 PF00400.27 KFM08084.1 - 2.5e-20 71.5 14.8 3.5e-08 33.0 0.0 6.7 7 2 0 7 7 7 4 WD domain, G-beta repeat F-box-like PF12937.2 KFM08084.1 - 3.3e-08 33.1 5.2 7.5e-08 31.9 2.3 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KFM08084.1 - 6.4e-06 25.6 0.9 4.5e-05 22.9 0.5 2.5 2 1 1 3 3 3 1 F-box domain Nup160 PF11715.3 KFM08084.1 - 0.065 11.3 6.8 1 7.4 0.3 3.0 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Sugar_tr PF00083.19 KFM08085.1 - 1.2e-96 324.1 24.9 1.3e-96 323.9 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFM08085.1 - 1.2e-28 99.8 28.2 1.2e-28 99.8 19.5 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 KFM08085.1 - 0.00053 18.5 3.1 0.00053 18.5 2.1 3.8 1 1 1 3 3 3 2 MFS/sugar transport protein CNH PF00780.17 KFM08086.1 - 1.4e-67 227.9 0.2 2.9e-67 226.9 0.2 1.5 1 0 0 1 1 1 1 CNH domain Rap_GAP PF02145.10 KFM08086.1 - 4.6e-64 215.2 0.0 8.5e-64 214.3 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP CRAL_TRIO PF00650.15 KFM08087.1 - 2e-19 69.6 0.0 2.5e-14 53.0 0.0 2.2 2 0 0 2 2 2 2 CRAL/TRIO domain GOLD_2 PF13897.1 KFM08087.1 - 0.032 14.4 0.0 0.072 13.3 0.0 1.6 1 1 0 1 1 1 0 Golgi-dynamics membrane-trafficking Gal-3-0_sulfotr PF06990.6 KFM08088.1 - 8.5e-154 512.0 2.5 9.5e-154 511.8 1.7 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Pescadillo_N PF06732.6 KFM08089.1 - 4.7e-119 396.7 1.3 4.7e-119 396.7 0.9 2.4 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 KFM08089.1 - 8.8e-10 38.5 0.0 4.9e-09 36.2 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Daxx PF03344.10 KFM08089.1 - 0.13 10.7 20.1 0.23 9.9 14.0 1.4 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 KFM08089.1 - 0.16 10.0 17.0 0.3 9.0 11.8 1.4 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.11 KFM08089.1 - 0.57 9.1 12.5 6.3 5.7 8.4 2.2 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit TraH_2 PF06871.6 KFM08089.1 - 2.4 7.5 7.3 5.3 6.4 5.1 1.5 1 0 0 1 1 1 0 TraH_2 FAM176 PF14851.1 KFM08089.1 - 4.1 7.0 18.7 11 5.7 13.0 1.6 1 0 0 1 1 1 0 FAM176 family CPSF100_C PF13299.1 KFM08089.1 - 9 6.4 14.4 1.2 9.2 6.6 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Cobalamin_bind PF01122.14 KFM08090.1 - 1.3e-60 204.7 0.0 1.4e-60 204.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic cobalamin-binding protein PH_8 PF15409.1 KFM08091.1 - 2.8e-05 24.0 0.0 9e-05 22.4 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain Oxysterol_BP PF01237.13 KFM08091.1 - 0.00079 18.0 0.2 0.0016 16.9 0.1 1.5 1 0 0 1 1 1 1 Oxysterol-binding protein PH PF00169.24 KFM08091.1 - 0.0016 18.6 0.0 0.0045 17.1 0.0 1.8 1 0 0 1 1 1 1 PH domain Syntaxin-6_N PF09177.6 KFM08091.1 - 0.0053 17.1 7.5 0.066 13.6 0.3 3.3 1 1 1 3 3 3 1 Syntaxin 6, N-terminal Herpes_IE68 PF02479.11 KFM08091.1 - 0.0058 15.8 0.8 0.025 13.7 0.1 2.2 2 0 0 2 2 2 1 Herpesvirus immediate early protein PH_6 PF15406.1 KFM08091.1 - 0.011 15.8 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain MbeD_MobD PF04899.7 KFM08091.1 - 0.067 13.1 1.6 0.22 11.4 0.3 2.2 2 0 0 2 2 2 0 MbeD/MobD like MerR-DNA-bind PF09278.6 KFM08091.1 - 0.28 11.5 7.4 0.19 12.1 2.4 2.4 2 1 0 2 2 2 0 MerR, DNA binding USP8_dimer PF08969.6 KFM08091.1 - 1.1 9.2 4.3 4.8 7.1 0.1 3.0 3 0 0 3 3 3 0 USP8 dimerisation domain Oxysterol_BP PF01237.13 KFM08092.1 - 5e-24 84.4 0.1 5.8e-24 84.2 0.1 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Glucosamine_iso PF01182.15 KFM08093.1 - 3.7e-23 82.3 0.0 5.3e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase GTP_EFTU PF00009.22 KFM08094.1 - 1.4e-52 177.8 0.2 2.1e-52 177.2 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 KFM08094.1 - 3.5e-23 81.5 0.5 3.5e-23 81.5 0.3 3.1 3 1 0 3 3 3 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 KFM08094.1 - 7.4e-20 70.6 0.0 2.9e-19 68.7 0.0 2.1 3 0 0 3 3 3 1 Elongation factor G C-terminus EFG_II PF14492.1 KFM08094.1 - 7.6e-07 28.8 0.0 2.7e-06 27.1 0.0 2.0 1 1 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 KFM08094.1 - 9.3e-07 28.8 0.0 2.1e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 KFM08094.1 - 1e-06 28.2 0.0 2e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Ras family GTP_EFTU_D2 PF03144.20 KFM08094.1 - 4.5e-06 26.6 0.1 1.2e-05 25.3 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SRPRB PF09439.5 KFM08094.1 - 0.0023 17.1 0.0 0.0061 15.7 0.0 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit CbiA PF01656.18 KFM08094.1 - 0.014 14.8 0.1 0.029 13.7 0.1 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Septin PF00735.13 KFM08094.1 - 0.027 13.4 0.8 0.21 10.5 0.0 2.3 2 0 0 2 2 2 0 Septin Miro PF08477.8 KFM08094.1 - 0.069 13.6 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Yip1 PF04893.12 KFM08095.1 - 1.8e-06 27.5 13.1 2.5e-06 27.0 9.1 1.3 1 0 0 1 1 1 1 Yip1 domain FMN_dh PF01070.13 KFM08095.1 - 0.088 11.6 0.1 0.12 11.1 0.1 1.1 1 0 0 1 1 1 0 FMN-dependent dehydrogenase DUF3488 PF11992.3 KFM08095.1 - 2.6 6.5 7.3 3.2 6.3 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) Glutaredoxin PF00462.19 KFM08096.1 - 1.9e-09 37.3 0.2 6.1e-09 35.7 0.1 1.9 1 0 0 1 1 1 1 Glutaredoxin SH3BGR PF04908.10 KFM08096.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein Zn-ribbon_8 PF09723.5 KFM08096.1 - 0.68 9.9 0.1 0.68 9.9 0.1 3.0 2 1 0 2 2 2 0 Zinc ribbon domain DnaJ_CXXCXGXG PF00684.14 KFM08096.1 - 0.69 10.0 14.9 18 5.4 0.1 2.6 1 1 1 2 2 2 0 DnaJ central domain Shisa PF13908.1 KFM08097.1 - 2.2e-14 54.0 1.2 2.9e-14 53.6 0.8 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF3446 PF11928.3 KFM08097.1 - 0.069 13.3 8.2 0.053 13.7 4.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3446) BEN PF10523.4 KFM08098.1 - 8e-12 45.0 0.0 1.8e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 BEN domain Leu_zip PF15294.1 KFM08098.1 - 0.0041 16.2 3.1 0.013 14.6 0.2 2.1 2 0 0 2 2 2 1 Leucine zipper bZIP_1 PF00170.16 KFM08098.1 - 0.0054 16.6 0.1 0.014 15.3 0.1 1.6 1 0 0 1 1 1 1 bZIP transcription factor Uds1 PF15456.1 KFM08098.1 - 0.012 15.6 0.7 0.047 13.6 0.5 1.9 1 1 0 1 1 1 0 Up-regulated During Septation Cep57_CLD_2 PF14197.1 KFM08098.1 - 0.017 15.0 0.3 0.084 12.8 0.1 2.0 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 NYD-SP28_assoc PF14775.1 KFM08098.1 - 0.031 13.9 1.6 0.075 12.7 1.1 1.6 1 0 0 1 1 1 0 Sperm tail C-terminal domain Thioredoxin_2 PF13098.1 KFM08098.1 - 0.038 14.1 0.1 0.082 13.1 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain bZIP_2 PF07716.10 KFM08098.1 - 0.043 13.6 3.8 0.1 12.4 2.7 1.6 1 0 0 1 1 1 0 Basic region leucine zipper Shugoshin_N PF07558.6 KFM08098.1 - 0.096 12.4 1.5 0.2 11.3 1.0 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Ribosomal_S17e PF00833.13 KFM08098.1 - 0.15 11.7 0.3 0.4 10.4 0.2 1.6 1 0 0 1 1 1 0 Ribosomal S17 zf-C4pol PF14260.1 KFM08098.1 - 3.1 7.8 7.3 0.46 10.5 1.1 2.3 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta IncA PF04156.9 KFM08098.1 - 5.5 6.5 10.0 0.2 11.2 2.3 1.8 2 0 0 2 2 2 0 IncA protein Cation_efflux PF01545.16 KFM08099.1 - 9.8e-43 146.2 1.2 9.8e-43 146.2 0.8 1.4 2 0 0 2 2 2 1 Cation efflux family DUF1319 PF07028.6 KFM08099.1 - 0.021 14.9 0.4 0.048 13.8 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) Ion_trans_N PF08412.5 KFM08099.1 - 0.072 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Ion transport protein N-terminal UPF0121 PF03661.8 KFM08100.1 - 2.1e-116 387.4 17.0 2.4e-116 387.2 11.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Homeobox PF00046.24 KFM08101.1 - 5.8e-13 48.2 0.8 8.9e-13 47.6 0.5 1.3 1 0 0 1 1 1 1 Homeobox domain LIM PF00412.17 KFM08102.1 - 4.5e-07 29.8 0.4 1e-06 28.6 0.2 1.7 1 0 0 1 1 1 1 LIM domain Peptidase_C12 PF01088.16 KFM08103.1 - 1.5e-57 194.2 0.7 1.6e-57 194.0 0.5 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 PID PF00640.18 KFM08104.1 - 2.3e-62 209.1 0.0 7e-30 103.8 0.0 2.4 2 0 0 2 2 2 2 Phosphotyrosine interaction domain (PTB/PID) WW PF00397.21 KFM08104.1 - 1.5e-06 27.9 1.4 3.3e-06 26.8 1.0 1.6 1 0 0 1 1 1 1 WW domain PTB PF08416.8 KFM08104.1 - 1.1e-05 25.3 0.0 0.0014 18.5 0.0 2.6 2 1 0 2 2 2 2 Phosphotyrosine-binding domain Nol1_Nop2_Fmu PF01189.12 KFM08105.1 - 0.0013 18.1 0.4 0.0034 16.8 0.2 1.7 1 1 0 1 1 1 1 NOL1/NOP2/sun family RRM_1 PF00076.17 KFM08106.1 - 4.4e-39 131.9 0.4 2e-15 56.1 0.0 3.8 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM08106.1 - 6.8e-28 96.4 0.5 5.7e-09 35.8 0.0 3.7 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM08106.1 - 1.6e-15 56.6 0.3 9.3e-06 25.3 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KFM08106.1 - 0.0079 15.9 0.1 0.21 11.3 0.0 2.8 3 0 0 3 3 3 1 Limkain b1 Nup35_RRM_2 PF14605.1 KFM08106.1 - 0.056 13.2 0.4 2 8.2 0.0 2.7 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Spo7_2_N PF15407.1 KFM08106.1 - 0.18 11.2 0.0 25 4.4 0.0 2.4 2 0 0 2 2 2 0 Sporulation protein family 7 Neur_chan_LBD PF02931.18 KFM08107.1 - 8.1e-67 224.5 2.1 1.1e-66 224.0 1.4 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFM08107.1 - 5.8e-43 147.4 0.1 8.3e-43 146.9 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Ras PF00071.17 KFM08110.1 - 6e-44 149.2 0.0 7e-44 149.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM08110.1 - 8.4e-20 71.4 0.0 1.2e-19 70.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM08110.1 - 1.1e-05 24.7 0.0 1.5e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFM08110.1 - 0.0023 17.8 0.0 0.0038 17.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.9 KFM08110.1 - 0.025 14.2 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 KFM08110.1 - 0.072 12.5 0.0 0.71 9.3 0.0 2.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF1771 PF08590.5 KFM08111.1 - 7e-17 61.2 4.9 1.8e-16 59.8 3.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) AAA_33 PF13671.1 KFM08111.1 - 3.6e-15 56.0 0.0 9.2e-15 54.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain Smr PF01713.16 KFM08111.1 - 1.3e-13 50.9 0.0 4.8e-13 49.0 0.0 2.1 1 0 0 1 1 1 1 Smr domain Zeta_toxin PF06414.7 KFM08111.1 - 5.7e-05 22.3 0.1 0.00032 19.8 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin AAA_17 PF13207.1 KFM08111.1 - 0.00011 22.9 0.0 0.00061 20.6 0.0 2.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KFM08111.1 - 0.00068 19.7 0.0 0.24 11.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KFM08111.1 - 0.0099 16.1 1.2 0.033 14.4 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KFM08111.1 - 0.036 14.0 0.0 0.14 12.1 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain VIT1 PF01988.14 KFM08111.1 - 0.61 9.5 0.3 1.6 8.2 0.2 1.7 1 0 0 1 1 1 0 VIT family HEAT_2 PF13646.1 KFM08112.1 - 3.9e-05 23.8 2.8 1.3 9.3 0.0 6.0 6 1 0 6 6 6 2 HEAT repeats HEAT PF02985.17 KFM08112.1 - 0.00048 19.9 4.0 42 4.5 0.0 7.2 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.1 KFM08112.1 - 0.35 11.4 4.6 73 4.0 0.0 5.4 6 0 0 6 6 6 0 HEAT-like repeat UQ_con PF00179.21 KFM08113.1 - 1.4e-41 141.2 0.1 1.7e-41 140.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.26 KFM08113.1 - 6.6e-09 35.3 0.0 1.3e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Prok-E2_B PF14461.1 KFM08113.1 - 6.3e-07 29.2 0.0 1.2e-06 28.2 0.0 1.6 1 1 1 2 2 2 1 Prokaryotic E2 family B RWD PF05773.17 KFM08113.1 - 0.0015 18.4 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 RWD domain UBA_3 PF09288.5 KFM08113.1 - 0.075 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain DUF2615 PF11027.3 KFM08114.1 - 1.4e-43 147.0 0.1 1.5e-43 146.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2615) UDPG_MGDP_dh_N PF03721.9 KFM08115.1 - 1.6e-59 200.3 0.0 2.7e-59 199.6 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 KFM08115.1 - 3e-36 123.7 0.0 3e-34 117.3 0.0 2.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 KFM08115.1 - 3.7e-34 116.8 0.0 1.1e-33 115.3 0.0 1.8 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain 3HCDH_N PF02737.13 KFM08115.1 - 0.0028 17.3 0.0 0.15 11.6 0.0 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KFM08115.1 - 0.008 15.9 0.0 0.17 11.6 0.0 2.4 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Ldh_1_N PF00056.18 KFM08115.1 - 0.01 15.6 0.0 3.1 7.6 0.0 3.7 2 2 2 4 4 4 0 lactate/malate dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KFM08115.1 - 0.011 16.1 0.0 5.9 7.4 0.0 3.4 3 1 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 KFM08115.1 - 0.011 15.9 0.0 6.6 7.0 0.0 2.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Saccharop_dh PF03435.13 KFM08115.1 - 0.044 12.7 0.0 0.064 12.2 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_2 PF03446.10 KFM08115.1 - 0.059 13.2 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 KFM08115.1 - 0.11 11.9 0.0 0.32 10.4 0.0 1.9 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Radical_SAM PF04055.16 KFM08116.1 - 8.8e-17 61.7 0.0 1.4e-16 61.1 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Ribosomal_L6 PF00347.18 KFM08117.1 - 5.6e-35 119.6 1.5 1.2e-16 60.9 0.2 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Glyco_hydro_1 PF00232.13 KFM08118.1 - 7.1e-164 545.3 16.6 2.1e-81 273.4 1.1 3.1 2 1 0 2 2 2 2 Glycosyl hydrolase family 1 Y_phosphatase3C PF13348.1 KFM08118.1 - 0.0053 16.8 0.0 0.014 15.5 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region RFC1 PF08519.7 KFM08119.1 - 8.1e-59 197.8 0.1 2.8e-58 196.0 0.0 2.1 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 KFM08119.1 - 8.4e-16 57.8 0.0 2.6e-15 56.3 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 KFM08119.1 - 4e-15 56.1 0.0 9.2e-15 55.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KFM08119.1 - 1.8e-07 31.9 0.0 9.9e-07 29.6 0.0 2.3 1 0 0 1 1 1 1 AAA domain PTCB-BRCT PF12738.2 KFM08119.1 - 8.2e-06 25.5 0.1 2.4e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain AAA_14 PF13173.1 KFM08119.1 - 5e-05 23.2 0.1 0.00037 20.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KFM08119.1 - 0.00017 21.7 0.0 0.00076 19.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFM08119.1 - 0.00051 19.7 0.0 0.0012 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 KFM08119.1 - 0.00054 20.1 0.1 0.0048 17.0 0.0 2.7 2 1 0 2 2 2 1 RNA helicase AAA_18 PF13238.1 KFM08119.1 - 0.00082 19.6 1.2 0.0025 18.1 0.1 2.5 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 KFM08119.1 - 0.0014 17.7 0.0 0.0032 16.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 KFM08119.1 - 0.0017 18.2 0.0 0.0044 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFM08119.1 - 0.016 15.1 0.0 0.062 13.2 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 KFM08119.1 - 0.072 12.8 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Clathrin PF00637.15 KFM08120.1 - 4.4e-13 49.0 7.2 0.00045 19.8 0.1 5.1 3 1 3 6 6 6 4 Region in Clathrin and VPS WD40 PF00400.27 KFM08120.1 - 1.5e-08 34.1 2.5 0.26 11.2 0.0 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KFM08120.1 - 2.6e-07 29.8 5.8 0.12 11.1 0.7 4.5 5 0 0 5 5 5 3 Coatomer WD associated region Apc3 PF12895.2 KFM08120.1 - 1.9e-06 27.9 9.2 1.2 9.3 0.0 6.0 4 2 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 KFM08120.1 - 6.3e-06 25.7 15.2 0.058 13.0 1.6 5.6 5 1 1 6 6 6 3 TPR repeat TPR_12 PF13424.1 KFM08120.1 - 3.3e-05 23.7 9.0 0.0038 17.1 0.9 5.3 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFM08120.1 - 0.0089 16.3 6.7 20 5.6 1.4 5.6 5 1 0 5 5 5 0 Tetratricopeptide repeat eIF2A PF08662.6 KFM08120.1 - 0.012 15.3 0.0 0.062 12.9 0.0 2.2 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A TPR_14 PF13428.1 KFM08120.1 - 0.019 15.5 11.1 10 7.0 0.2 7.4 6 2 2 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFM08120.1 - 0.021 14.6 11.5 2.4 8.1 0.2 6.1 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 KFM08120.1 - 0.049 13.5 21.4 0.85 9.6 0.3 7.2 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFM08120.1 - 0.072 12.9 14.7 29 4.7 0.1 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat DZR PF12773.2 KFM08120.1 - 0.075 12.8 12.0 0.93 9.3 8.1 2.5 1 1 0 1 1 1 0 Double zinc ribbon TMEM156 PF15106.1 KFM08121.1 - 2.8e-87 291.6 15.4 3.2e-87 291.5 10.7 1.0 1 0 0 1 1 1 1 TMEM156 protein family Renin_r PF07850.9 KFM08121.1 - 0.8 10.0 3.5 0.28 11.5 0.4 1.7 2 0 0 2 2 2 0 Renin receptor-like protein DUF2500 PF10694.4 KFM08121.1 - 8 6.5 7.4 0.41 10.6 0.5 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2500) DUF719 PF05334.8 KFM08122.1 - 2.8e-57 193.6 0.4 2.8e-57 193.6 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF719) TIR PF01582.15 KFM08123.1 - 5.4e-35 119.8 0.2 1.6e-34 118.3 0.1 1.9 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.2 KFM08123.1 - 1.9e-15 56.1 30.9 2.6e-08 33.2 1.0 7.1 5 1 4 9 9 9 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM08123.1 - 2.3e-15 56.0 27.7 2.2e-07 30.4 3.5 5.9 3 1 4 7 7 7 5 Leucine rich repeat TIR_2 PF13676.1 KFM08123.1 - 6.7e-11 42.2 0.0 1.5e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.28 KFM08123.1 - 2.1e-09 36.0 21.9 0.03 14.3 0.3 8.9 8 1 1 9 9 9 4 Leucine Rich Repeat LRR_6 PF13516.1 KFM08123.1 - 2.2e-09 36.3 18.3 0.084 12.9 0.0 8.1 7 0 0 7 7 7 3 Leucine Rich repeat LRR_7 PF13504.1 KFM08123.1 - 1.5e-05 24.3 21.0 0.36 11.2 0.1 9.0 9 0 0 9 9 9 2 Leucine rich repeat Pentapeptide_4 PF13599.1 KFM08123.1 - 0.019 14.7 5.8 2.2 8.1 0.9 3.9 1 1 1 2 2 2 0 Pentapeptide repeats (9 copies) LRRCT PF01463.19 KFM08123.1 - 0.049 13.9 0.0 0.25 11.7 0.0 2.4 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain LRR_9 PF14580.1 KFM08123.1 - 0.45 10.0 2.9 1.2 8.6 0.4 2.3 1 1 0 2 2 2 0 Leucine-rich repeat DUF1098 PF06497.6 KFM08123.1 - 0.5 10.4 5.9 1.1 9.3 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1098) TIR PF01582.15 KFM08124.1 - 6.3e-35 119.6 0.2 1.2e-34 118.7 0.1 1.5 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.2 KFM08124.1 - 2.9e-17 61.8 19.9 2.1e-08 33.6 1.0 6.0 6 1 2 8 8 8 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM08124.1 - 7.5e-14 51.2 27.1 1.7e-07 30.8 3.4 4.7 1 1 3 4 4 4 4 Leucine rich repeat LRR_6 PF13516.1 KFM08124.1 - 1.6e-11 43.0 11.4 0.07 13.2 0.0 6.7 5 1 1 6 6 6 4 Leucine Rich repeat TIR_2 PF13676.1 KFM08124.1 - 5e-11 42.6 0.0 1.1e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.28 KFM08124.1 - 6.8e-10 37.5 18.5 0.025 14.5 0.3 8.0 7 1 1 8 8 8 4 Leucine Rich Repeat LRR_7 PF13504.1 KFM08124.1 - 4e-05 23.1 19.2 0.3 11.4 0.1 7.9 7 0 0 7 7 7 2 Leucine rich repeat LRRCT PF01463.19 KFM08124.1 - 0.033 14.4 0.0 0.21 11.9 0.0 2.5 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain LRR_9 PF14580.1 KFM08124.1 - 0.5 9.9 2.5 0.77 9.3 0.2 2.1 2 0 0 2 2 2 0 Leucine-rich repeat zf-C2H2 PF00096.21 KFM08125.1 - 5.4e-14 51.5 24.9 2.6e-06 27.4 1.9 3.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM08125.1 - 3.3e-13 49.2 8.2 2e-09 37.2 0.8 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM08125.1 - 2.2e-09 36.9 20.2 0.0014 18.8 1.0 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 KFM08125.1 - 0.012 15.7 3.3 2.2 8.5 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFM08125.1 - 0.11 12.7 3.6 3.4 7.9 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFM08125.1 - 1.1 9.2 6.5 0.42 10.6 0.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger RabGAP-TBC PF00566.13 KFM08126.1 - 4.4e-52 176.6 0.9 1.2e-51 175.2 0.6 1.8 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3350 PF11830.3 KFM08126.1 - 1.1e-25 89.3 2.9 4.5e-25 87.4 2.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3350) PID PF00640.18 KFM08126.1 - 8.9e-14 51.6 5.2 1.6e-09 37.8 0.3 3.5 3 0 0 3 3 3 2 Phosphotyrosine interaction domain (PTB/PID) FANCI_S1-cap PF14674.1 KFM08126.1 - 0.79 9.8 4.1 7.6 6.6 0.1 2.8 2 0 0 2 2 2 0 FANCI solenoid 1 cap PGM_PMM_I PF02878.11 KFM08127.1 - 2.1e-36 124.4 0.0 4e-36 123.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 KFM08127.1 - 9e-24 83.7 0.0 2.5e-23 82.3 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 KFM08127.1 - 2e-11 43.8 0.2 7.8e-11 42.0 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 KFM08127.1 - 1.8e-05 24.6 0.0 5.1e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RELT PF12606.3 KFM08128.1 - 4.7e-22 76.8 0.8 8.5e-22 76.0 0.5 1.4 1 0 0 1 1 1 1 Tumour necrosis factor receptor superfamily member 19 TMEM171 PF15471.1 KFM08128.1 - 0.023 13.4 0.2 0.057 12.2 0.0 1.7 2 0 0 2 2 2 0 Transmembrane protein family 171 DUF506 PF04720.7 KFM08129.1 - 0.14 11.7 1.7 0.26 10.9 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF506) AAA_22 PF13401.1 KFM08130.1 - 3.3e-06 27.2 0.0 1.7e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KFM08130.1 - 2.5e-05 24.0 0.1 7.2e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_28 PF13521.1 KFM08130.1 - 0.00079 19.4 0.0 0.0019 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain PQQ_2 PF13360.1 KFM08130.1 - 0.0021 17.5 0.1 0.091 12.2 0.0 2.7 2 0 0 2 2 2 1 PQQ-like domain AAA PF00004.24 KFM08130.1 - 0.0028 17.8 0.2 0.014 15.5 0.0 2.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KFM08130.1 - 0.018 14.4 0.0 0.045 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KFM08130.1 - 0.061 13.2 0.3 0.82 9.6 0.2 2.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 KFM08130.1 - 0.32 10.7 0.0 0.85 9.4 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Dynein_heavy PF03028.10 KFM08132.1 - 0 1034.8 0.0 0 1033.3 0.0 1.9 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor MT PF12777.2 KFM08132.1 - 3.4e-200 664.0 13.9 5.8e-200 663.2 9.6 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.2 KFM08132.1 - 1.2e-164 545.9 0.5 1.5e-162 539.1 0.1 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 DHC_N1 PF08385.7 KFM08132.1 - 6e-164 546.6 0.4 6e-164 546.6 0.3 4.3 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 AAA_8 PF12780.2 KFM08132.1 - 1.9e-159 528.7 0.2 5.4e-159 527.2 0.1 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_6 PF12774.2 KFM08132.1 - 1.3e-155 515.6 0.1 3.8e-155 514.1 0.0 1.9 2 0 0 2 2 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 KFM08132.1 - 1.2e-137 456.1 0.2 2.8e-137 454.8 0.1 1.7 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 DHC_N2 PF08393.8 KFM08132.1 - 1.3e-123 412.5 1.3 1.3e-123 412.5 0.9 4.3 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_5 PF07728.9 KFM08132.1 - 6.4e-29 100.4 0.0 7.5e-14 51.6 0.0 6.3 6 1 0 6 6 5 4 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KFM08132.1 - 4e-07 30.1 0.0 0.46 10.4 0.0 5.0 4 0 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 KFM08132.1 - 1e-06 28.8 1.3 0.058 13.5 0.0 4.9 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.1 KFM08132.1 - 8.5e-06 25.4 1.2 0.039 13.5 0.0 3.9 4 0 0 4 4 4 1 AAA domain AAA_17 PF13207.1 KFM08132.1 - 0.00067 20.4 6.6 1.7 9.5 0.0 6.2 7 0 0 7 7 5 1 AAA domain AAA_19 PF13245.1 KFM08132.1 - 0.00075 19.1 1.8 8.6 6.2 0.0 4.0 3 0 0 3 3 3 0 Part of AAA domain AAA PF00004.24 KFM08132.1 - 0.00079 19.6 0.4 0.86 9.8 0.0 4.6 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KFM08132.1 - 0.0015 18.0 0.0 0.69 9.3 0.0 3.1 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_18 PF13238.1 KFM08132.1 - 0.0051 17.1 0.7 7.8 6.8 0.0 4.6 4 0 0 4 4 4 0 AAA domain RNA_helicase PF00910.17 KFM08132.1 - 0.0062 16.6 0.1 13 6.0 0.0 4.1 3 0 0 3 3 3 0 RNA helicase Sigma54_activ_2 PF14532.1 KFM08132.1 - 0.011 15.8 0.0 4.9 7.1 0.0 3.5 2 0 0 2 2 2 0 Sigma-54 interaction domain CbiN PF02553.10 KFM08132.1 - 0.021 14.7 0.0 0.063 13.2 0.0 1.7 1 0 0 1 1 1 0 Cobalt transport protein component CbiN AAA_29 PF13555.1 KFM08132.1 - 0.057 12.9 0.1 29 4.2 0.0 3.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_25 PF13481.1 KFM08132.1 - 0.062 12.7 0.2 2.7 7.3 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 KFM08132.1 - 0.18 11.7 1.6 51 3.7 0.0 4.0 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.22 KFM08132.1 - 0.29 11.4 4.8 45 4.3 0.0 5.1 5 0 0 5 5 4 0 ABC transporter GSu_C4xC__C2xCH PF09698.5 KFM08132.1 - 2.2 8.5 0.0 5.3 7.2 0.0 1.7 1 0 0 1 1 1 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) Reo_sigmaC PF04582.7 KFM08132.1 - 3.8 6.6 5.6 42 3.1 0.0 3.7 3 0 0 3 3 3 0 Reovirus sigma C capsid protein Gp58 PF07902.6 KFM08132.1 - 4.7 5.2 7.3 0.3 9.2 0.0 2.1 2 0 0 2 2 2 0 gp58-like protein Lactamase_B_2 PF12706.2 KFM08133.1 - 3.8e-31 108.1 0.1 1.2e-30 106.5 0.1 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KFM08133.1 - 2e-08 34.1 0.0 3.1e-07 30.2 0.0 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Pkinase PF00069.20 KFM08134.1 - 1.4e-58 198.0 0.0 1.8e-58 197.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM08134.1 - 8.7e-39 133.1 0.0 1.1e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM08134.1 - 7.7e-11 41.4 0.0 1.1e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KFM08134.1 - 0.00012 21.0 0.1 0.00018 20.4 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 DXP_redisom_C PF08436.7 KFM08134.1 - 0.01 15.7 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal APH PF01636.18 KFM08134.1 - 0.05 13.3 0.0 0.079 12.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family TMEM220 PF15071.1 KFM08136.1 - 1.5e-10 41.3 1.1 2.3e-10 40.8 0.1 1.7 2 0 0 2 2 2 1 Transmembrane family 220, helix DUF2878 PF11086.3 KFM08136.1 - 0.095 12.6 2.4 0.11 12.5 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2878) V-set PF07686.12 KFM08144.1 - 1.5e-11 44.2 0.0 2.3e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 KFM08144.1 - 4.6e-09 36.0 0.4 1.2e-08 34.6 0.3 1.8 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 KFM08144.1 - 2.5e-05 24.3 0.4 0.021 14.9 0.0 2.7 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.1 KFM08144.1 - 0.00014 21.9 0.2 0.00029 20.8 0.1 1.5 1 1 0 1 1 1 1 Immunoglobulin domain Herpes_gE PF02480.11 KFM08144.1 - 0.081 11.1 0.0 0.084 11.1 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Ig_3 PF13927.1 KFM08144.1 - 0.091 13.2 0.0 0.85 10.1 0.0 2.1 1 1 0 1 1 1 0 Immunoglobulin domain DUF1684 PF07920.6 KFM08144.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1684) FH2 PF02181.18 KFM08145.1 - 2.6e-87 293.1 8.2 2.6e-87 293.1 5.7 2.1 2 1 0 2 2 2 1 Formin Homology 2 Domain CTD_bind PF04818.8 KFM08146.1 - 1e-25 89.7 0.4 4e-25 87.8 0.0 2.2 3 0 0 3 3 3 1 RNA polymerase II-binding domain. Snapin_Pallidin PF14712.1 KFM08146.1 - 0.084 13.1 1.9 0.19 12.0 0.6 2.0 2 0 0 2 2 2 0 Snapin/Pallidin PhoU PF01895.14 KFM08146.1 - 0.12 12.8 1.8 1.3 9.4 0.5 2.4 2 0 0 2 2 2 0 PhoU domain UBN_AB PF14075.1 KFM08146.1 - 0.23 11.0 2.9 0.13 11.8 0.6 1.6 2 0 0 2 2 2 0 Ubinuclein conserved middle domain IncA PF04156.9 KFM08146.1 - 7.6 6.0 7.9 0.55 9.8 1.3 2.0 2 1 0 2 2 2 0 IncA protein Rpr2 PF04032.11 KFM08147.1 - 0.048 13.5 0.8 0.048 13.5 0.5 2.3 3 0 0 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Glycos_transf_2 PF00535.21 KFM08148.1 - 4.3e-35 120.8 0.0 6.9e-35 120.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 KFM08148.1 - 9.6e-29 99.9 3.8 1.6e-28 99.2 2.2 1.6 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.1 KFM08148.1 - 3.6e-11 43.3 0.0 5.3e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 KFM08148.1 - 7.4e-07 28.5 0.1 1.6e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase RicinB_lectin_2 PF14200.1 KFM08148.1 - 3.1e-06 27.5 0.1 0.0016 18.7 0.0 2.6 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Glyco_tranf_2_2 PF10111.4 KFM08148.1 - 3.9e-05 22.8 0.0 0.00032 19.8 0.0 2.3 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KFM08148.1 - 0.027 14.2 0.1 0.064 12.9 0.1 1.7 1 1 0 1 1 1 0 Glycosyl transferase family group 2 YL1_C PF08265.6 KFM08149.1 - 8.6e-13 47.6 0.1 8.6e-13 47.6 0.0 2.1 3 0 0 3 3 3 1 YL1 nuclear protein C-terminal domain UPF0118 PF01594.11 KFM08150.1 - 1.7e-10 40.4 29.8 8.5e-10 38.1 13.1 3.6 4 1 0 4 4 4 2 Domain of unknown function DUF20 DOMON PF03351.12 KFM08151.1 - 1.5e-23 83.1 0.0 1.8e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 DOMON domain Yae1_N PF09811.4 KFM08152.1 - 4.6e-11 42.0 28.4 0.23 11.0 19.7 3.1 1 1 0 1 1 1 1 Essential protein Yae1, N terminal FERM_C PF09380.5 KFM08153.1 - 2.3e-21 75.8 0.0 4.1e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.13 KFM08153.1 - 2.3e-19 69.7 0.2 4.2e-19 68.9 0.1 1.4 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.5 KFM08153.1 - 9.3e-19 67.2 1.3 2.9e-18 65.6 0.2 2.4 3 1 0 3 3 3 1 FERM N-terminal domain FA PF08736.6 KFM08153.1 - 1e-12 47.6 10.1 2.1e-12 46.6 7.0 1.6 1 0 0 1 1 1 1 FERM adjacent (FA) ACBP PF00887.14 KFM08153.1 - 0.027 14.1 0.0 0.058 13.0 0.0 1.6 1 0 0 1 1 1 0 Acyl CoA binding protein Y_phosphatase PF00102.22 KFM08155.1 - 1.8e-79 266.3 1.5 3.9e-79 265.2 1.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase FERM_C PF09380.5 KFM08155.1 - 8.7e-23 80.3 1.6 2.3e-22 78.9 1.1 1.8 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.13 KFM08155.1 - 2.3e-22 79.4 0.2 6.2e-22 78.1 0.2 1.8 1 0 0 1 1 1 1 FERM central domain PDZ PF00595.19 KFM08155.1 - 1.6e-20 73.0 0.1 4.4e-20 71.6 0.0 1.8 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) FERM_N PF09379.5 KFM08155.1 - 3e-19 68.8 0.0 7.3e-19 67.6 0.0 1.7 1 0 0 1 1 1 1 FERM N-terminal domain DSPc PF00782.15 KFM08155.1 - 1.3e-05 24.8 0.1 3e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 KFM08155.1 - 0.00072 19.6 0.3 0.0018 18.3 0.2 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 KFM08155.1 - 0.0015 18.7 0.0 0.0033 17.7 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PDZ_2 PF13180.1 KFM08155.1 - 0.027 14.3 0.0 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 PDZ domain MOSC_N PF03476.11 KFM08156.1 - 4.7e-31 106.9 0.0 9e-31 106.0 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 KFM08156.1 - 9e-24 83.4 0.0 1.7e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 MOSC domain Aminotran_5 PF00266.14 KFM08156.1 - 1.9e-21 76.2 0.0 5.8e-21 74.6 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V KH_1 PF00013.24 KFM08157.1 - 1.1e-52 175.4 13.9 1.3e-17 63.1 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KFM08157.1 - 3.9e-40 134.8 20.0 1.1e-13 50.4 0.3 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KFM08157.1 - 7.9e-17 60.5 6.5 1.7e-05 24.3 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KFM08157.1 - 3.3e-08 33.0 2.2 0.0094 15.5 0.3 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 KFM08157.1 - 1.1e-05 25.1 5.7 0.32 10.8 0.1 3.3 3 0 0 3 3 3 3 NusA-like KH domain DUF370 PF04025.7 KFM08157.1 - 0.017 15.1 0.9 3.6 7.7 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF370) DUF3696 PF12476.3 KFM08158.1 - 0.077 12.9 1.7 25 4.9 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3696) BAG PF02179.11 KFM08159.1 - 7.6e-12 45.1 4.4 3.2e-11 43.1 3.1 2.0 1 1 0 1 1 1 1 BAG domain ubiquitin PF00240.18 KFM08159.1 - 4.4e-08 32.4 0.3 1.1e-07 31.1 0.0 1.9 2 0 0 2 2 1 1 Ubiquitin family PHTB1_C PF14728.1 KFM08159.1 - 3.9e-06 25.9 1.2 4.3e-06 25.7 0.8 1.1 1 0 0 1 1 1 1 PTHB1 C-terminus YPEB PF14620.1 KFM08159.1 - 0.00037 19.6 0.5 0.00054 19.0 0.3 1.3 1 0 0 1 1 1 1 YpeB sporulation V_ATPase_I PF01496.14 KFM08159.1 - 0.0058 14.5 1.3 0.0063 14.4 0.9 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF342 PF03961.8 KFM08159.1 - 0.013 13.9 4.8 0.017 13.5 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Nup54 PF13874.1 KFM08159.1 - 0.063 12.9 3.9 1.7 8.3 0.1 2.4 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 Sigma54_DBD PF04552.8 KFM08159.1 - 0.081 12.4 0.7 0.13 11.7 0.5 1.4 1 1 0 1 1 1 0 Sigma-54, DNA binding domain Uds1 PF15456.1 KFM08159.1 - 0.09 12.7 1.8 0.2 11.6 0.3 2.1 1 1 1 2 2 2 0 Up-regulated During Septation NYD-SP28 PF14772.1 KFM08159.1 - 0.091 12.8 5.4 0.18 11.9 2.6 2.0 2 0 0 2 2 2 0 Sperm tail Fib_alpha PF08702.5 KFM08159.1 - 0.12 12.5 2.5 0.19 11.8 1.7 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF2408 PF10303.4 KFM08159.1 - 0.13 12.4 4.5 0.18 11.9 2.7 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Spectrin PF00435.16 KFM08159.1 - 0.13 12.5 5.1 1.4 9.2 2.5 2.4 2 0 0 2 2 2 0 Spectrin repeat Occludin_ELL PF07303.8 KFM08159.1 - 0.15 12.7 3.0 0.48 11.1 1.7 2.1 1 1 0 1 1 1 0 Occludin homology domain DUF148 PF02520.12 KFM08159.1 - 0.25 11.1 5.3 1.6 8.5 0.8 2.4 1 1 0 2 2 2 0 Domain of unknown function DUF148 MscS_porin PF12795.2 KFM08159.1 - 0.25 10.6 7.1 0.088 12.1 3.0 1.6 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Baculo_PEP_C PF04513.7 KFM08159.1 - 0.26 11.0 1.7 0.69 9.7 1.2 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus MitMem_reg PF13012.1 KFM08159.1 - 0.29 11.2 2.6 1.9 8.5 1.2 2.4 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function WXG100 PF06013.7 KFM08159.1 - 0.43 10.6 2.2 8.6 6.4 0.0 2.6 2 1 1 3 3 2 0 Proteins of 100 residues with WXG Erp_C PF06780.6 KFM08159.1 - 0.45 10.3 6.5 2.3 8.0 4.2 2.1 1 1 1 2 2 2 0 Erp protein C-terminus IncA PF04156.9 KFM08159.1 - 0.57 9.7 7.1 1.1 8.8 5.0 1.5 1 1 0 1 1 1 0 IncA protein SPAM PF02090.10 KFM08159.1 - 0.61 10.0 4.0 16 5.4 0.0 2.4 2 0 0 2 2 2 0 Salmonella surface presentation of antigen gene type M protein DUF1319 PF07028.6 KFM08159.1 - 0.66 10.1 5.8 0.74 10.0 2.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) DUF1664 PF07889.7 KFM08159.1 - 0.66 9.7 4.1 2.2 8.0 1.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.17 KFM08159.1 - 0.98 9.4 11.3 1 9.3 5.6 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain GrpE PF01025.14 KFM08159.1 - 1.1 8.7 7.5 2 7.9 5.2 1.5 1 1 0 1 1 1 0 GrpE BLOC1_2 PF10046.4 KFM08159.1 - 1.3 9.2 7.3 23 5.2 3.8 3.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.7 KFM08159.1 - 2 8.7 5.1 3.1 8.1 1.5 2.7 3 1 0 3 3 2 0 Nucleopolyhedrovirus P10 protein Prefoldin PF02996.12 KFM08159.1 - 2.1 8.0 10.0 0.84 9.3 1.0 2.7 2 1 1 3 3 3 0 Prefoldin subunit Laminin_II PF06009.7 KFM08159.1 - 2.6 7.7 7.5 1.3 8.7 0.7 2.7 2 1 1 3 3 3 0 Laminin Domain II Snf7 PF03357.16 KFM08160.1 - 2.6e-50 170.1 20.4 3.1e-50 169.9 14.2 1.0 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.7 KFM08160.1 - 0.0007 19.8 1.5 0.0007 19.8 1.0 2.8 1 1 2 3 3 3 1 Nucleopolyhedrovirus P10 protein BCDHK_Adom3 PF10436.4 KFM08160.1 - 0.057 12.9 2.3 0.078 12.4 1.6 1.3 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Phage_lysozyme PF00959.14 KFM08160.1 - 0.067 13.4 0.8 0.1 12.9 0.6 1.4 1 0 0 1 1 1 0 Phage lysozyme Prefoldin_2 PF01920.15 KFM08160.1 - 0.081 12.6 22.0 0.52 10.0 0.6 3.4 2 1 1 3 3 3 0 Prefoldin subunit BTV_NS2 PF04514.7 KFM08160.1 - 0.13 11.1 11.0 0.16 10.8 7.6 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF45 PF01863.12 KFM08160.1 - 0.87 9.3 6.4 0.9 9.2 3.8 1.4 1 1 1 2 2 2 0 Protein of unknown function DUF45 DUF848 PF05852.6 KFM08160.1 - 0.89 9.4 10.4 0.37 10.6 4.7 2.1 1 1 2 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) GvpK PF05121.7 KFM08160.1 - 0.91 9.3 11.5 0.85 9.4 1.7 3.1 2 1 0 3 3 3 0 Gas vesicle protein K His_binding PF02098.11 KFM08160.1 - 0.98 9.2 4.6 1.8 8.3 3.2 1.5 1 1 0 1 1 1 0 Tick histamine binding protein PRA-PH PF01503.12 KFM08160.1 - 1.3 9.3 4.4 3.1 8.1 3.0 1.8 1 1 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase DUF948 PF06103.6 KFM08160.1 - 1.9 8.3 5.9 1.7 8.5 2.4 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) IncA PF04156.9 KFM08160.1 - 4.9 6.6 11.9 31 4.0 8.3 2.0 1 1 0 1 1 1 0 IncA protein CorA PF01544.13 KFM08160.1 - 5.7 5.8 15.7 6.1 5.7 6.1 2.9 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein PEP-utilisers_N PF05524.8 KFM08160.1 - 9.2 6.0 10.5 1.2 8.9 0.9 2.4 1 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal Lyase_1 PF00206.15 KFM08161.1 - 1.7e-122 408.5 0.2 2.1e-122 408.1 0.1 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 KFM08161.1 - 2.1e-28 98.1 0.2 1.6e-27 95.3 0.0 2.2 2 0 0 2 2 2 1 Fumarase C C-terminus FAD_binding_2 PF00890.19 KFM08162.1 - 6.6e-127 423.8 2.6 8.2e-127 423.5 1.8 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 KFM08162.1 - 2.5e-43 146.9 0.0 4.3e-43 146.2 0.0 1.4 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 KFM08162.1 - 1.8e-07 31.2 0.0 0.0055 16.6 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFM08162.1 - 3.4e-06 26.3 0.4 0.03 13.4 0.0 2.4 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 KFM08162.1 - 0.00014 20.8 0.1 0.0038 16.1 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 KFM08162.1 - 0.00016 20.6 3.4 0.055 12.3 1.5 2.5 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_3 PF01494.14 KFM08162.1 - 0.0048 15.9 0.2 0.0077 15.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KFM08162.1 - 0.18 10.2 1.7 0.73 8.2 0.2 2.5 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox_3 PF13738.1 KFM08162.1 - 0.21 11.5 0.9 1.2 9.1 0.4 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PIN_3 PF13470.1 KFM08163.1 - 0.33 11.6 3.2 1.6 9.4 2.2 2.3 1 1 0 1 1 1 0 PIN domain Exonuc_VII_L PF02601.10 KFM08163.1 - 1.7 7.7 6.8 2 7.5 4.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.14 KFM08163.1 - 2.8 5.6 7.0 3.5 5.3 4.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.1 KFM08163.1 - 3.2 8.0 9.3 5.5 7.2 6.5 1.4 1 0 0 1 1 1 0 AAA domain OmpH PF03938.9 KFM08163.1 - 7.5 6.4 14.6 3.6e+02 1.0 10.1 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) SNF PF00209.13 KFM08164.1 - 2.6e-175 583.8 29.0 3.3e-175 583.4 20.1 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.13 KFM08165.1 - 2.2e-177 590.6 28.3 2.9e-177 590.2 19.6 1.2 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Telomerase_RBD PF12009.3 KFM08166.1 - 4e-41 140.1 6.5 1.5e-40 138.2 4.5 2.1 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 KFM08166.1 - 1.4e-13 50.7 0.0 2.5e-12 46.5 0.0 2.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CLPTM1 PF05602.7 KFM08167.1 - 5.7e-131 437.2 3.5 7e-131 436.9 2.4 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) Acyltransferase PF01553.16 KFM08168.1 - 1.7e-16 59.8 0.0 3e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase EF-hand_6 PF13405.1 KFM08168.1 - 7.3e-11 40.9 0.4 0.0022 17.7 0.0 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 KFM08168.1 - 1.3e-08 34.7 3.0 0.00076 19.5 0.1 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KFM08168.1 - 1.7e-08 33.1 3.8 0.00012 21.1 0.1 4.4 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 KFM08168.1 - 1.8e-08 33.8 5.3 0.0026 17.3 0.1 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KFM08168.1 - 0.00088 18.5 0.9 0.0089 15.3 0.2 3.0 4 0 0 4 4 4 1 EF hand EF-hand_4 PF12763.2 KFM08168.1 - 0.017 14.8 0.2 0.37 10.5 0.0 2.3 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand PI3K_p85B PF02192.11 KFM08168.1 - 0.029 13.7 0.3 2.9 7.3 0.0 2.6 2 0 0 2 2 2 0 PI3-kinase family, p85-binding domain zf-CHCC PF10276.4 KFM08169.1 - 2.1e-19 69.0 0.7 2.5e-19 68.8 0.5 1.1 1 0 0 1 1 1 1 Zinc-finger domain COX5B PF01215.14 KFM08169.1 - 0.048 13.3 0.1 0.053 13.1 0.1 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Vb RhoGAP PF00620.22 KFM08170.1 - 8.3e-49 165.0 0.0 2.1e-48 163.8 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain Tropomyosin_1 PF12718.2 KFM08170.1 - 0.01 15.7 11.6 0.021 14.6 8.1 1.6 1 0 0 1 1 1 1 Tropomyosin like DUF2748 PF10871.3 KFM08170.1 - 0.028 12.8 0.4 4.5 5.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2748) PAH PF02671.16 KFM08170.1 - 0.066 12.8 0.4 0.79 9.3 0.1 2.5 2 0 0 2 2 2 0 Paired amphipathic helix repeat PH PF00169.24 KFM08170.1 - 0.15 12.2 0.1 0.15 12.2 0.0 2.8 2 1 0 2 2 2 0 PH domain DMPK_coil PF08826.5 KFM08170.1 - 1.8 8.5 16.1 3.6 7.5 4.9 3.0 1 1 1 2 2 2 0 DMPK coiled coil domain like IncA PF04156.9 KFM08170.1 - 6.8 6.2 14.1 4.6 6.7 7.7 2.1 2 1 0 2 2 2 0 IncA protein Pkinase PF00069.20 KFM08171.1 - 7e-67 225.3 0.0 8.8e-67 224.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM08171.1 - 5.2e-31 107.6 0.1 7.2e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFM08171.1 - 3.8e-07 29.3 0.1 5.9e-07 28.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KFM08171.1 - 0.00019 20.5 0.1 0.00034 19.6 0.1 1.4 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KFM08171.1 - 0.00023 20.5 0.3 0.00044 19.6 0.2 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KFM08171.1 - 0.00045 20.0 0.0 0.00072 19.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Y_phosphatase PF00102.22 KFM08172.1 - 5.2e-69 232.1 0.0 6.1e-69 231.9 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFM08172.1 - 6.9e-05 22.4 0.0 0.00013 21.5 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 KFM08172.1 - 0.0028 17.7 0.0 0.0045 17.0 0.0 1.6 1 1 0 1 1 1 1 Inositol hexakisphosphate Kelch_1 PF01344.20 KFM08173.1 - 7.9e-71 233.4 9.7 1.2e-14 53.5 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 KFM08173.1 - 2.4e-46 154.0 4.7 3.3e-09 36.5 0.0 6.4 4 1 2 6 6 6 6 Kelch motif Kelch_3 PF13415.1 KFM08173.1 - 2.7e-31 106.9 8.7 1.1e-06 28.6 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.10 KFM08173.1 - 4.6e-30 102.2 9.8 3.5e-05 23.3 0.0 6.5 6 0 0 6 6 6 6 Kelch motif BACK PF07707.10 KFM08173.1 - 1.3e-27 95.5 0.7 1.3e-27 95.5 0.5 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_4 PF13418.1 KFM08173.1 - 5e-27 93.4 6.8 7.6e-06 25.6 0.0 6.5 5 1 1 6 6 6 6 Galactose oxidase, central domain BTB PF00651.26 KFM08173.1 - 6.1e-25 87.3 2.7 9.1e-25 86.8 1.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Kelch_5 PF13854.1 KFM08173.1 - 9.3e-08 31.8 9.8 0.55 10.2 0.0 6.0 6 0 0 6 6 6 3 Kelch motif adh_short PF00106.20 KFM08174.1 - 5.7e-22 78.3 1.0 9.4e-22 77.6 0.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFM08174.1 - 1.1e-07 31.9 0.0 1.5e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFM08174.1 - 1.2e-07 31.6 0.5 1.9e-07 30.9 0.4 1.3 1 0 0 1 1 1 1 KR domain Ureidogly_hydro PF04115.7 KFM08174.1 - 0.028 13.7 0.1 0.043 13.1 0.1 1.3 1 0 0 1 1 1 0 Ureidoglycolate hydrolase adh_short PF00106.20 KFM08175.1 - 6.1e-22 78.3 1.0 9.4e-22 77.6 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFM08175.1 - 1.1e-07 31.9 0.0 1.5e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFM08175.1 - 1.2e-07 31.6 0.5 1.9e-07 30.9 0.4 1.3 1 0 0 1 1 1 1 KR domain Ureidogly_hydro PF04115.7 KFM08175.1 - 0.028 13.7 0.1 0.043 13.1 0.1 1.3 1 0 0 1 1 1 0 Ureidoglycolate hydrolase NUDIX PF00293.23 KFM08176.1 - 1.7e-09 37.4 0.2 6.2e-09 35.6 0.1 1.8 1 1 0 1 1 1 1 NUDIX domain SPARC_Ca_bdg PF10591.4 KFM08177.1 - 1.6e-42 144.0 1.1 2.6e-42 143.3 0.8 1.4 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Kazal_1 PF00050.16 KFM08177.1 - 9.3e-12 44.7 6.8 9.3e-12 44.7 4.7 2.2 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain FOLN PF09289.5 KFM08177.1 - 6.1e-10 38.7 10.7 6.1e-10 38.7 7.4 2.2 2 0 0 2 2 2 1 Follistatin/Osteonectin-like EGF domain Kazal_2 PF07648.10 KFM08177.1 - 2.6e-09 36.8 3.5 7.9e-09 35.3 2.4 1.9 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain EF-hand_7 PF13499.1 KFM08177.1 - 0.082 13.0 1.1 2.3 8.4 0.7 2.4 1 1 0 1 1 1 0 EF-hand domain pair Imm-NTF2 PF15655.1 KFM08177.1 - 0.084 13.3 0.3 0.23 11.9 0.1 1.8 1 1 1 2 2 2 0 NTF2 fold immunity protein DMP1 PF07263.6 KFM08178.1 - 1.3e-09 37.3 54.5 1.6e-09 37.0 37.8 1.2 1 0 0 1 1 1 1 Dentin matrix protein 1 (DMP1) BSP_II PF05432.6 KFM08179.1 - 1.5e-56 191.8 56.4 3.6e-32 111.8 32.3 2.1 2 0 0 2 2 2 2 Bone sialoprotein II (BSP-II) Nop14 PF04147.7 KFM08179.1 - 0.47 8.3 15.6 0.55 8.0 10.8 1.3 1 0 0 1 1 1 0 Nop14-like family Osteopontin PF00865.13 KFM08181.1 - 1.5e-34 119.5 14.5 1.5e-17 63.7 0.6 2.0 1 1 1 2 2 2 2 Osteopontin Na_trans_assoc PF06512.8 KFM08181.1 - 0.013 15.4 0.9 0.015 15.2 0.6 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated Senescence_reg PF04520.8 KFM08181.1 - 0.42 11.1 9.8 0.43 11.0 6.2 1.4 1 1 0 1 1 1 0 Senescence regulator NicO PF03824.11 KFM08181.1 - 0.46 9.7 4.8 0.57 9.4 3.4 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein FAM176 PF14851.1 KFM08181.1 - 1.5 8.5 6.8 8.3 6.0 0.0 2.1 1 1 1 2 2 2 0 FAM176 family Macoilin PF09726.4 KFM08181.1 - 1.6 6.9 6.9 2 6.6 4.8 1.0 1 0 0 1 1 1 0 Transmembrane protein PKD_channel PF08016.7 KFM08182.1 - 1.8e-158 527.4 18.0 1.8e-158 527.4 12.5 1.9 2 0 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.26 KFM08182.1 - 1.9e-22 79.5 29.3 1.9e-22 79.5 20.3 1.9 2 0 0 2 2 2 1 Ion transport protein Gag_p30 PF02093.11 KFM08183.1 - 8.1e-28 97.0 0.2 9.7e-28 96.8 0.1 1.0 1 0 0 1 1 1 1 Gag P30 core shell protein Gag_p24 PF00607.15 KFM08183.1 - 0.0026 17.3 0.1 0.0029 17.1 0.1 1.1 1 0 0 1 1 1 1 gag gene protein p24 (core nucleocapsid protein) MAM PF00629.18 KFM08183.1 - 0.15 11.7 0.3 0.57 9.9 0.0 1.8 2 0 0 2 2 2 0 MAM domain ABC2_membrane PF01061.19 KFM08184.1 - 7.6e-33 113.4 25.2 7.6e-33 113.4 17.4 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 KFM08184.1 - 2.2e-22 79.8 0.3 8e-22 78.0 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 KFM08184.1 - 3.8e-08 33.6 1.9 4.2e-06 26.9 0.1 3.0 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 KFM08184.1 - 5.9e-05 22.3 0.1 0.032 13.4 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KFM08184.1 - 0.00029 21.2 0.0 0.00029 21.2 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.1 KFM08184.1 - 0.001 18.2 1.1 3.5 6.5 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain ABC2_membrane_3 PF12698.2 KFM08184.1 - 0.0017 17.4 29.1 0.006 15.6 20.1 1.9 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_17 PF13207.1 KFM08184.1 - 0.0048 17.7 0.0 0.047 14.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KFM08184.1 - 0.0066 15.9 0.1 0.016 14.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain PDR_assoc PF08370.6 KFM08184.1 - 0.0077 15.7 0.5 0.032 13.7 0.4 2.1 1 0 0 1 1 1 1 Plant PDR ABC transporter associated AAA_16 PF13191.1 KFM08184.1 - 0.023 14.7 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 KFM08184.1 - 0.045 14.0 0.2 0.14 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KFM08184.1 - 0.12 12.4 0.1 0.49 10.5 0.0 2.1 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KFM08184.1 - 0.13 11.9 1.3 3.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase DUF87 PF01935.12 KFM08184.1 - 0.29 10.9 2.3 0.41 10.4 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function DUF87 PLAC8 PF04749.12 KFM08185.1 - 7e-17 61.9 19.6 2.8e-16 59.9 13.6 1.8 1 1 0 1 1 1 1 PLAC8 family Tat PF00539.13 KFM08185.1 - 4 7.1 11.1 0.74 9.4 0.3 2.3 2 0 0 2 2 2 0 Transactivating regulatory protein (Tat) PLAC8 PF04749.12 KFM08186.1 - 6.7e-17 61.9 29.1 4e-16 59.4 20.2 1.8 1 1 0 1 1 1 1 PLAC8 family UbiA PF01040.13 KFM08187.1 - 3.9e-31 108.2 10.1 4.6e-31 107.9 7.0 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family Glyco_hydro_79n PF03662.9 KFM08188.1 - 3.7e-23 81.6 0.1 1.9e-22 79.2 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 79, N-terminal domain Ribosomal_S18 PF01084.15 KFM08189.1 - 1.3e-21 76.2 0.0 3.6e-21 74.7 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S18 Rubella_E1 PF05748.6 KFM08189.1 - 0.1 11.1 0.0 0.12 11.0 0.0 1.0 1 0 0 1 1 1 0 Rubella membrane glycoprotein E1 Tropomyosin PF00261.15 KFM08191.1 - 0.00046 19.3 3.1 0.00046 19.3 2.1 2.1 2 0 0 2 2 2 1 Tropomyosin DUF2508 PF10704.4 KFM08191.1 - 1.2 9.3 6.2 10 6.3 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) Cluap1 PF10234.4 KFM08191.1 - 2.3 7.3 9.3 0.062 12.4 1.4 1.8 2 0 0 2 2 2 0 Clusterin-associated protein-1 APG6 PF04111.7 KFM08191.1 - 2.4 7.1 12.0 0.27 10.2 1.1 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF948 PF06103.6 KFM08191.1 - 2.6 7.9 7.6 0.25 11.2 1.5 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) IncA PF04156.9 KFM08191.1 - 5.6 6.5 13.2 0.32 10.5 3.5 2.1 2 0 0 2 2 2 0 IncA protein Acyltransferase PF01553.16 KFM08192.1 - 4.1e-11 42.4 0.1 6.7e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransferase PF01553.16 KFM08193.1 - 4.3e-19 68.2 0.1 7.8e-19 67.4 0.1 1.4 1 0 0 1 1 1 1 Acyltransferase ELFV_dehydrog_N PF02812.13 KFM08193.1 - 0.073 12.6 0.1 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain CTP_transf_1 PF01148.15 KFM08194.1 - 3e-86 289.2 24.1 3.7e-86 288.9 16.7 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Beach PF02138.13 KFM08196.1 - 8.2e-114 379.6 0.1 1.5e-113 378.7 0.1 1.4 1 0 0 1 1 1 1 Beige/BEACH domain FYVE PF01363.16 KFM08196.1 - 3.7e-18 65.1 12.5 8.9e-18 63.9 8.7 1.7 1 0 0 1 1 1 1 FYVE zinc finger PH_BEACH PF14844.1 KFM08196.1 - 8.8e-15 54.4 0.0 2.8e-14 52.8 0.0 1.9 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 KFM08196.1 - 5e-14 51.5 11.8 3.1e-08 33.1 0.3 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat Laminin_G_3 PF13385.1 KFM08196.1 - 2.2e-06 28.0 0.0 5.1e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PP2C PF00481.16 KFM08197.1 - 1.2e-55 188.6 0.3 1.6e-55 188.2 0.2 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KFM08197.1 - 2.4e-15 56.5 0.0 4.5e-15 55.6 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KFM08197.1 - 0.0008 19.1 0.2 0.31 10.7 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Beach PF02138.13 KFM08198.1 - 5e-111 370.4 0.4 1e-110 369.4 0.3 1.5 1 0 0 1 1 1 1 Beige/BEACH domain DUF1088 PF06469.6 KFM08198.1 - 1.3e-87 291.5 1.4 2.5e-87 290.5 0.9 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1088) PH_BEACH PF14844.1 KFM08198.1 - 2.4e-30 104.4 0.0 9.3e-29 99.3 0.0 3.3 3 0 0 3 3 3 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.1 KFM08198.1 - 2.9e-17 63.3 0.1 1.2e-16 61.3 0.1 2.0 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.27 KFM08198.1 - 2.4e-13 49.3 3.8 0.00027 20.6 0.1 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat Mab-21 PF03281.9 KFM08199.1 - 1.7e-89 299.8 0.0 2.3e-89 299.4 0.0 1.2 1 0 0 1 1 1 1 Mab-21 protein Pkinase PF00069.20 KFM08200.1 - 3.3e-72 242.7 0.0 4.9e-72 242.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DCX PF03607.12 KFM08200.1 - 1.5e-44 149.3 0.3 1.1e-22 79.3 0.0 2.7 2 0 0 2 2 2 2 Doublecortin Pkinase_Tyr PF07714.12 KFM08200.1 - 7.8e-33 113.6 0.0 1.3e-32 112.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM08200.1 - 0.0027 16.7 0.0 0.013 14.4 0.0 1.9 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFM08200.1 - 0.16 11.0 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C4 PF00105.13 KFM08201.1 - 1.1e-28 99.1 12.9 2.1e-28 98.3 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 KFM08201.1 - 6.8e-10 38.3 0.0 1.5e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor RhoGAP PF00620.22 KFM08203.1 - 1e-39 135.5 0.1 1e-39 135.5 0.0 2.7 3 0 0 3 3 3 1 RhoGAP domain SH3_9 PF14604.1 KFM08203.1 - 3.5e-11 42.5 0.0 7.4e-11 41.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM08203.1 - 2.5e-07 29.9 0.0 4.8e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFM08203.1 - 3.9e-05 23.0 0.0 8.8e-05 21.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 KFM08203.1 - 0.012 15.7 0.0 0.047 13.8 0.0 2.0 1 0 0 1 1 1 0 PH domain IMD PF08397.6 KFM08203.1 - 1 8.6 13.4 0.59 9.4 7.7 1.8 2 0 0 2 2 2 0 IRSp53/MIM homology domain Arfaptin PF06456.8 KFM08203.1 - 1.4 8.1 19.1 6.6 6.0 10.0 3.7 3 1 0 3 3 3 0 Arfaptin-like domain Complex1_LYR_2 PF13233.1 KFM08203.1 - 4.2 7.9 12.0 0.26 11.7 1.1 3.1 2 1 1 3 3 3 0 Complex1_LYR-like PrmA PF06325.8 KFM08204.1 - 2.2e-10 40.1 0.0 8.1e-10 38.2 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) TPR_2 PF07719.12 KFM08204.1 - 8.7e-08 31.5 0.9 0.0022 17.7 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat Methyltransf_18 PF12847.2 KFM08204.1 - 2e-07 31.5 0.0 5.6e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain TPR_11 PF13414.1 KFM08204.1 - 2.2e-07 30.4 0.6 3.1e-06 26.7 0.0 2.5 2 0 0 2 2 2 1 TPR repeat Methyltransf_26 PF13659.1 KFM08204.1 - 2.1e-05 24.5 0.0 5.2e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain TPR_1 PF00515.23 KFM08204.1 - 5e-05 22.7 0.9 0.22 11.1 0.0 2.9 3 0 0 3 3 2 2 Tetratricopeptide repeat MTS PF05175.9 KFM08204.1 - 0.00012 21.5 0.0 0.00026 20.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain TPR_14 PF13428.1 KFM08204.1 - 0.00018 21.8 1.1 0.045 14.4 0.0 3.2 2 1 1 3 3 2 1 Tetratricopeptide repeat CMAS PF02353.15 KFM08204.1 - 0.00084 18.4 0.1 0.0031 16.6 0.0 1.9 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.4 KFM08204.1 - 0.0011 18.5 0.1 0.0035 16.8 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_11 PF08241.7 KFM08204.1 - 0.0015 18.9 0.0 0.0063 16.9 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFM08204.1 - 0.003 17.1 0.0 0.0077 15.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain TPR_16 PF13432.1 KFM08204.1 - 0.0041 17.7 1.2 0.04 14.6 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Methyltransf_23 PF13489.1 KFM08204.1 - 0.0043 16.7 0.0 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 KFM08204.1 - 0.0069 15.2 0.0 0.014 14.2 0.0 1.4 1 0 0 1 1 1 1 DREV methyltransferase RrnaAD PF00398.15 KFM08204.1 - 0.013 14.4 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Met_10 PF02475.11 KFM08204.1 - 0.019 14.5 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 Met-10+ like-protein TPR_17 PF13431.1 KFM08204.1 - 0.04 14.1 0.1 1.5 9.2 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Methyltransf_25 PF13649.1 KFM08204.1 - 0.048 14.0 0.0 0.13 12.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Solute_trans_a PF03619.11 KFM08205.1 - 1.3e-99 332.9 18.3 1.5e-99 332.7 12.7 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha 7tm_1 PF00001.16 KFM08206.1 - 3.3e-38 131.2 10.3 3.3e-38 131.2 7.1 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM08206.1 - 0.006 15.7 15.6 0.072 12.2 8.4 3.4 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx TPR_12 PF13424.1 KFM08207.1 - 2.3e-16 59.4 19.1 1.5e-07 31.2 0.5 4.4 1 1 6 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.1 KFM08207.1 - 4.6e-12 45.3 15.2 0.0003 20.3 0.2 5.0 4 1 1 5 5 5 3 TPR repeat TPR_1 PF00515.23 KFM08207.1 - 3.1e-08 32.8 12.6 8.3e-05 22.0 0.2 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFM08207.1 - 3.2e-07 29.7 13.8 0.0089 15.8 0.1 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFM08207.1 - 1.2e-06 27.8 13.1 0.0033 17.0 0.1 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFM08207.1 - 5e-05 22.8 4.1 0.15 11.9 0.0 5.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFM08207.1 - 8.8e-05 22.8 5.1 9.8 7.1 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 KFM08207.1 - 0.00051 19.8 0.1 0.0067 16.3 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFM08207.1 - 0.00074 19.5 7.1 18 5.8 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFM08207.1 - 0.0033 18.0 4.7 1.7 9.3 0.0 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 KFM08207.1 - 0.0052 16.9 15.3 0.013 15.6 0.8 4.1 2 1 2 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 Aminotran_3 PF00202.16 KFM08207.1 - 0.007 15.2 0.9 0.017 13.9 0.2 1.7 1 1 1 2 2 2 1 Aminotransferase class-III SHNi-TPR PF10516.4 KFM08207.1 - 0.02 14.1 0.1 1.7 7.9 0.1 2.7 2 0 0 2 2 2 0 SHNi-TPR Sel1 PF08238.7 KFM08207.1 - 0.082 13.5 0.1 0.082 13.5 0.1 3.1 4 0 0 4 4 2 0 Sel1 repeat TPR_19 PF14559.1 KFM08207.1 - 0.085 13.2 7.6 0.47 10.8 0.0 3.9 2 1 3 5 5 4 0 Tetratricopeptide repeat Cation_ATPase_N PF00690.21 KFM08207.1 - 0.088 12.2 0.4 2.4 7.6 0.0 2.5 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus TPR_20 PF14561.1 KFM08207.1 - 0.094 12.8 9.3 13 6.0 0.0 5.3 3 1 2 6 6 6 0 Tetratricopeptide repeat RPN7 PF10602.4 KFM08207.1 - 0.75 9.1 6.7 0.38 10.1 0.1 3.1 2 1 1 3 3 3 0 26S proteasome subunit RPN7 TPR_6 PF13174.1 KFM08207.1 - 0.82 10.2 8.2 40 4.9 0.0 5.0 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 KFM08207.1 - 2.2 8.9 7.7 27 5.5 0.0 4.2 5 0 0 5 5 3 0 Tetratricopeptide repeat Pou PF00157.12 KFM08208.1 - 1.3e-31 108.0 0.0 1.6e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain HTH_31 PF13560.1 KFM08208.1 - 0.0015 18.7 0.0 0.0026 17.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 KFM08208.1 - 0.01 15.8 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3236 PF11576.3 KFM08208.1 - 0.087 12.2 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) DUF4137 PF13593.1 KFM08209.1 - 1.9e-60 204.5 18.5 2.1e-60 204.4 12.8 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.11 KFM08209.1 - 1.9e-15 56.7 13.4 1.9e-15 56.7 9.3 1.7 2 0 0 2 2 2 1 Sodium Bile acid symporter family DUF1301 PF06979.7 KFM08209.1 - 1.4 9.1 8.5 0.13 12.3 1.8 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1301) MRAP PF15183.1 KFM08209.1 - 1.8 8.2 6.2 0.14 11.7 0.4 2.1 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family Reeler PF02014.11 KFM08210.1 - 4.2e-27 94.9 0.0 4.8e-27 94.7 0.0 1.0 1 0 0 1 1 1 1 Reeler domain DHFR_2 PF06442.6 KFM08210.1 - 0.092 12.3 0.1 0.66 9.6 0.0 2.1 2 0 0 2 2 2 0 R67 dihydrofolate reductase LSM PF01423.17 KFM08211.1 - 5.4e-18 64.2 0.1 6.2e-18 64.1 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KFM08211.1 - 2.5e-05 24.1 0.0 2.9e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain zf-C2H2 PF00096.21 KFM08212.1 - 2.1e-14 52.9 80.2 0.00025 21.2 0.2 9.2 9 0 0 9 9 9 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM08212.1 - 2.2e-11 43.2 74.0 0.0048 17.1 3.7 9.3 9 0 0 9 9 9 6 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFM08212.1 - 8.9e-11 41.5 77.2 0.00054 20.1 3.2 11.1 11 1 0 11 11 11 6 Zinc-finger double domain zf-H2C2_5 PF13909.1 KFM08212.1 - 6.8e-09 35.4 77.3 0.021 15.0 4.0 9.0 8 0 0 8 8 8 5 C2H2-type zinc-finger domain zf-met PF12874.2 KFM08212.1 - 0.0071 16.5 64.4 0.39 11.0 1.8 9.2 9 0 0 9 9 8 6 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFM08212.1 - 0.014 15.3 0.2 0.014 15.3 0.1 5.1 4 1 0 4 4 3 0 C2H2-type zinc finger Terminase_GpA PF05876.7 KFM08212.1 - 0.034 12.5 0.9 0.061 11.6 0.6 1.3 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) zf-C2H2_jaz PF12171.3 KFM08212.1 - 0.37 10.9 0.0 0.079 13.1 0.4 7.9 9 0 0 9 9 7 0 Zinc-finger double-stranded RNA-binding GAGA PF09237.6 KFM08212.1 - 0.79 9.3 0.0 0.79 9.3 0.0 4.9 5 0 0 5 5 5 0 GAGA factor PRP21_like_P PF12230.3 KFM08212.1 - 4.8 6.6 14.8 0.33 10.4 0.4 3.5 4 0 0 4 4 4 0 Pre-mRNA splicing factor PRP21 like protein zf-Sec23_Sec24 PF04810.10 KFM08212.1 - 5.8 6.5 21.6 10 5.7 0.0 6.8 7 1 1 8 8 8 0 Sec23/Sec24 zinc finger zf-C2H2_7 PF15269.1 KFM08212.1 - 6.5 6.7 45.0 0.14 12.0 0.8 7.6 5 2 3 8 8 8 0 Zinc-finger ArgK PF03308.11 KFM08213.1 - 1.2e-92 309.5 0.2 1.6e-92 309.0 0.1 1.2 1 0 0 1 1 1 1 ArgK protein cobW PF02492.14 KFM08213.1 - 1.1e-05 24.9 0.0 4.4e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 KFM08213.1 - 0.00012 22.2 1.1 0.0043 17.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain ATP_bind_1 PF03029.12 KFM08213.1 - 0.00023 20.7 0.0 0.00051 19.6 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MobB PF03205.9 KFM08213.1 - 0.0017 18.0 0.1 0.02 14.6 0.0 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KFM08213.1 - 0.0037 17.1 0.4 0.052 13.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KFM08213.1 - 0.0041 16.5 0.2 0.0064 15.9 0.0 1.6 2 0 0 2 2 2 1 AAA-like domain AAA_19 PF13245.1 KFM08213.1 - 0.0072 16.0 0.2 0.032 13.9 0.0 2.1 3 0 0 3 3 3 1 Part of AAA domain ABC_tran PF00005.22 KFM08213.1 - 0.0091 16.3 0.1 0.033 14.5 0.0 2.0 2 1 0 2 2 1 1 ABC transporter Thymidylate_kin PF02223.12 KFM08213.1 - 0.0097 15.2 0.0 0.025 13.9 0.0 1.7 1 0 0 1 1 1 1 Thymidylate kinase NTPase_1 PF03266.10 KFM08213.1 - 0.01 15.5 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 1 NTPase AAA_16 PF13191.1 KFM08213.1 - 0.013 15.5 0.5 0.067 13.1 0.0 2.0 1 1 1 2 2 2 0 AAA ATPase domain AAA_30 PF13604.1 KFM08213.1 - 0.018 14.6 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.1 KFM08213.1 - 0.025 14.5 0.0 0.27 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 KFM08213.1 - 0.026 13.6 0.1 0.64 9.1 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.1 KFM08213.1 - 0.028 14.7 0.1 0.055 13.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KFM08213.1 - 0.033 13.6 0.0 0.067 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain CbiA PF01656.18 KFM08213.1 - 0.04 13.3 0.0 0.075 12.4 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 KFM08213.1 - 0.041 14.6 0.4 0.12 13.1 0.1 1.9 2 0 0 2 2 1 0 AAA domain HD_assoc PF13286.1 KFM08213.1 - 0.045 14.0 0.1 0.39 11.0 0.0 2.4 2 1 0 2 2 2 0 Phosphohydrolase-associated domain AAA_18 PF13238.1 KFM08213.1 - 0.058 13.6 0.2 0.25 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 KFM08213.1 - 0.065 13.1 0.0 0.24 11.3 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase KTI12 PF08433.5 KFM08213.1 - 0.097 11.8 0.1 0.23 10.6 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MH2 PF03166.9 KFM08214.1 - 7.9e-78 260.4 0.2 1e-77 260.0 0.2 1.1 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.11 KFM08214.1 - 1.7e-42 143.5 1.2 4.6e-42 142.1 0.8 1.8 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.4 KFM08214.1 - 8.3e-07 28.7 1.6 8.9e-07 28.6 0.0 1.8 2 0 0 2 2 2 1 Interferon-regulatory factor 3 DUF605 PF04652.11 KFM08214.1 - 1.1 8.6 8.8 1.2 8.4 6.1 1.1 1 0 0 1 1 1 0 Vta1 like OTU PF02338.14 KFM08215.1 - 1.4e-15 57.9 0.1 3e-15 56.8 0.1 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 KFM08215.1 - 0.001 18.4 0.3 0.21 10.8 0.1 2.3 1 1 1 2 2 2 2 Peptidase C65 Otubain SMN PF06003.7 KFM08215.1 - 0.024 13.7 0.0 0.024 13.7 0.0 3.8 4 1 1 5 5 5 0 Survival motor neuron protein (SMN) ABC_tran PF00005.22 KFM08216.1 - 6.2e-38 130.1 0.0 1.2e-18 67.6 0.0 2.3 2 0 0 2 2 2 2 ABC transporter RLI PF04068.10 KFM08216.1 - 2.1e-15 55.9 7.0 6e-15 54.5 4.9 1.9 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 KFM08216.1 - 4.7e-12 46.4 3.5 0.041 13.8 0.1 4.9 3 2 1 4 4 4 3 AAA domain SMC_N PF02463.14 KFM08216.1 - 1.4e-10 40.7 3.3 0.0019 17.5 0.0 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KFM08216.1 - 9.9e-09 34.7 0.2 0.2 10.6 0.0 4.2 4 0 0 4 4 4 3 AAA ATPase domain AAA_16 PF13191.1 KFM08216.1 - 2.6e-08 34.0 0.0 0.00011 22.2 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain Fer4 PF00037.22 KFM08216.1 - 7.3e-07 28.5 1.7 7.3e-07 28.5 1.2 3.6 4 0 0 4 4 3 1 4Fe-4S binding domain AAA_22 PF13401.1 KFM08216.1 - 2.7e-06 27.5 0.1 0.0022 18.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KFM08216.1 - 1.2e-05 24.7 0.1 0.061 12.8 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.24 KFM08216.1 - 2.2e-05 24.6 0.0 0.036 14.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 KFM08216.1 - 2.6e-05 23.4 2.0 0.083 12.0 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 KFM08216.1 - 7.4e-05 23.5 0.3 0.59 10.9 0.1 3.0 2 2 0 2 2 2 2 AAA domain Miro PF08477.8 KFM08216.1 - 0.00013 22.4 0.6 0.62 10.5 0.0 3.5 3 1 0 3 3 3 1 Miro-like protein NACHT PF05729.7 KFM08216.1 - 0.00013 21.6 0.5 0.029 14.0 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Fer4_6 PF12837.2 KFM08216.1 - 0.00017 21.3 1.2 0.00017 21.3 0.8 3.4 4 0 0 4 4 2 1 4Fe-4S binding domain AAA_33 PF13671.1 KFM08216.1 - 0.00052 19.9 0.0 0.053 13.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KFM08216.1 - 0.00055 20.2 0.0 0.45 10.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KFM08216.1 - 0.0012 18.2 0.0 0.54 9.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KFM08216.1 - 0.0018 17.9 0.4 0.39 10.4 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 KFM08216.1 - 0.002 18.4 0.1 0.13 12.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KFM08216.1 - 0.0021 18.2 0.0 1.8 8.8 0.0 3.3 3 0 0 3 3 3 1 RNA helicase Fer4_21 PF14697.1 KFM08216.1 - 0.0026 17.5 1.5 0.0026 17.5 1.1 2.3 2 1 2 4 4 3 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 KFM08216.1 - 0.0026 17.5 2.0 0.0026 17.5 1.4 3.1 3 0 0 3 3 2 1 4Fe-4S binding domain SRP54 PF00448.17 KFM08216.1 - 0.0029 17.0 1.9 0.28 10.5 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain VirE PF05272.6 KFM08216.1 - 0.0043 16.5 0.0 0.98 8.8 0.0 2.4 2 0 0 2 2 2 1 Virulence-associated protein E Fer4_7 PF12838.2 KFM08216.1 - 0.0057 17.0 1.6 0.0057 17.0 1.1 3.2 2 1 2 4 4 4 1 4Fe-4S dicluster domain UPF0079 PF02367.12 KFM08216.1 - 0.0062 16.1 0.2 0.089 12.4 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Fer4_10 PF13237.1 KFM08216.1 - 0.014 15.1 2.0 0.014 15.1 1.4 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_24 PF13479.1 KFM08216.1 - 0.017 14.6 0.5 0.33 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 KFM08216.1 - 0.018 14.9 0.1 3.4 7.6 0.0 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Fer4_9 PF13187.1 KFM08216.1 - 0.019 15.2 1.9 0.019 15.2 1.3 3.2 2 1 2 4 4 4 0 4Fe-4S dicluster domain Fer4_16 PF13484.1 KFM08216.1 - 0.021 15.5 0.6 0.021 15.5 0.4 3.0 3 0 0 3 3 2 0 4Fe-4S double cluster binding domain AAA_28 PF13521.1 KFM08216.1 - 0.021 14.7 0.4 4.1 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 KFM08216.1 - 0.048 12.3 0.0 2.2 6.8 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein NB-ARC PF00931.17 KFM08216.1 - 0.057 12.2 0.1 3.2 6.5 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain ArgK PF03308.11 KFM08216.1 - 0.063 12.0 0.2 6.3 5.4 0.0 2.2 2 0 0 2 2 2 0 ArgK protein AAA_5 PF07728.9 KFM08216.1 - 0.068 12.8 1.1 0.95 9.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 KFM08216.1 - 0.093 12.2 0.1 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 KFM08216.1 - 0.13 12.2 0.0 18 5.2 0.0 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 KFM08216.1 - 0.2 11.0 0.3 4.2 6.7 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family Fer4_8 PF13183.1 KFM08216.1 - 0.6 10.1 11.6 0.12 12.3 1.2 2.5 2 1 1 3 3 2 0 4Fe-4S dicluster domain AAA_10 PF12846.2 KFM08216.1 - 1.7 8.0 4.9 11 5.3 0.1 2.8 3 1 0 3 3 3 0 AAA-like domain APC10 PF03256.11 KFM08217.1 - 3.1e-79 265.0 0.1 3.6e-79 264.8 0.1 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) CHB_HEX_C_1 PF13290.1 KFM08217.1 - 0.0057 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain PITH PF06201.8 KFM08217.1 - 0.018 14.7 0.1 0.075 12.8 0.1 1.8 1 1 0 1 1 1 0 PITH domain GSDH PF07995.6 KFM08218.1 - 9.9e-19 67.5 0.0 1.5e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase EGF_2 PF07974.8 KFM08218.1 - 0.00063 19.8 8.0 0.00063 19.8 5.5 3.2 3 0 0 3 3 3 2 EGF-like domain hEGF PF12661.2 KFM08218.1 - 1.5 9.0 14.5 1.6 9.0 0.9 3.3 2 0 0 2 2 2 0 Human growth factor-like EGF LRR_6 PF13516.1 KFM08219.1 - 1e-14 52.8 15.6 0.0007 19.4 0.1 9.7 10 0 0 10 10 10 4 Leucine Rich repeat LRR_4 PF12799.2 KFM08219.1 - 4.2e-07 29.4 19.3 0.0057 16.2 2.2 5.7 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM08219.1 - 9.3e-05 21.9 17.1 7.9 6.9 0.2 7.7 7 1 0 7 7 7 3 Leucine Rich Repeat LRR_8 PF13855.1 KFM08219.1 - 0.00017 21.2 15.4 0.038 13.7 0.7 5.4 5 1 1 6 6 6 3 Leucine rich repeat LRR_7 PF13504.1 KFM08219.1 - 0.05 13.7 20.1 2.6 8.6 0.1 7.8 8 0 0 8 8 8 0 Leucine rich repeat Ank PF00023.25 KFM08220.1 - 4.5e-22 76.6 0.1 1.5e-05 24.5 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 KFM08220.1 - 3.3e-21 75.4 0.1 1.7e-12 47.5 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFM08220.1 - 2.6e-16 59.6 0.1 4.6e-08 33.3 0.0 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM08220.1 - 1.7e-15 56.6 0.1 6.5e-08 32.5 0.0 3.2 2 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM08220.1 - 4.2e-12 45.0 0.1 0.018 15.2 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat AIRS_C PF02769.17 KFM08220.1 - 0.077 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 AIR synthase related protein, C-terminal domain IncA PF04156.9 KFM08220.1 - 4.5 6.8 13.8 11 5.5 9.5 1.6 1 0 0 1 1 1 0 IncA protein Ank_2 PF12796.2 KFM08222.1 - 1.9e-28 98.6 1.9 3.8e-15 55.9 0.1 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFM08222.1 - 4.3e-19 67.2 0.0 2.9e-07 29.9 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KFM08222.1 - 6e-19 68.0 0.8 8.8e-09 35.6 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM08222.1 - 2.7e-16 59.2 2.0 1e-09 38.3 0.1 2.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM08222.1 - 1.4e-11 43.4 0.1 0.0019 18.2 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat HMG-CoA_red PF00368.13 KFM08223.1 - 3.4e-167 555.8 1.2 4.4e-167 555.4 0.8 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.3 KFM08223.1 - 5.1e-17 61.7 3.6 1.1e-16 60.7 2.5 1.5 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 KFM08223.1 - 6.7e-09 34.2 3.0 1e-08 33.6 2.0 1.2 1 0 0 1 1 1 1 Patched family Med18 PF09637.5 KFM08224.1 - 2.8e-38 131.8 0.0 4.7e-35 121.3 0.0 2.0 1 1 0 1 1 1 1 Med18 protein START PF01852.14 KFM08225.1 - 7.5e-30 103.8 0.4 1.7e-29 102.6 0.2 1.6 1 0 0 1 1 1 1 START domain PH PF00169.24 KFM08225.1 - 5.6e-12 45.7 1.0 1.7e-11 44.2 0.7 1.9 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 KFM08225.1 - 4.6e-09 36.2 0.2 1.5e-08 34.5 0.1 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 KFM08225.1 - 0.00039 20.6 2.5 0.0064 16.7 1.8 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain Acyl_CoA_thio PF02551.10 KFM08225.1 - 0.012 15.2 0.0 0.027 14.0 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA thioesterase Ank_2 PF12796.2 KFM08227.1 - 5.6e-45 151.5 11.3 1.5e-18 66.9 2.6 3.6 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFM08227.1 - 9.6e-44 145.0 9.8 4.7e-08 32.4 0.0 7.4 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.1 KFM08227.1 - 1e-33 115.0 12.4 2e-10 40.8 0.5 5.3 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM08227.1 - 9.2e-33 111.5 5.8 5.8e-10 39.0 0.1 6.1 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM08227.1 - 1.7e-32 108.1 10.9 7.5e-07 28.7 0.1 7.3 7 0 0 7 7 7 6 Ankyrin repeat Death PF00531.17 KFM08227.1 - 6.8e-06 25.7 2.2 7.7e-06 25.5 0.6 1.9 2 0 0 2 2 2 1 Death domain zf-C4H2 PF10146.4 KFM08228.1 - 0.054 13.5 15.8 2.6 7.9 11.0 2.3 1 1 0 1 1 1 0 Zinc finger-containing protein Jacalin PF01419.12 KFM08228.1 - 0.08 12.8 0.4 0.32 10.8 0.0 2.1 2 0 0 2 2 2 0 Jacalin-like lectin domain Bacillus_HBL PF05791.6 KFM08228.1 - 0.099 12.0 5.5 0.47 9.8 0.1 2.3 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF3510 PF12022.3 KFM08228.1 - 0.12 12.4 1.7 0.29 11.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) CENP-F_leu_zip PF10473.4 KFM08228.1 - 0.13 12.0 17.1 0.84 9.4 6.0 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FliJ PF02050.11 KFM08228.1 - 2 8.4 18.5 1.2 9.1 0.2 3.0 2 1 1 3 3 3 0 Flagellar FliJ protein MFS_1 PF07690.11 KFM08230.1 - 2.5e-35 121.8 32.1 3.5e-25 88.4 10.7 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFM08230.1 - 4.4e-32 111.2 18.8 4.5e-29 101.3 2.5 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter Pentapeptide_4 PF13599.1 KFM08230.1 - 1.9e-12 46.7 9.1 3.3e-12 46.0 6.3 1.3 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 KFM08230.1 - 0.00015 21.5 6.9 0.00015 21.5 4.7 2.3 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) DUF1228 PF06779.9 KFM08230.1 - 0.0035 17.3 1.3 0.0035 17.3 0.9 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1228) MFS_1_like PF12832.2 KFM08230.1 - 0.098 12.4 4.0 0.32 10.8 0.0 3.4 4 0 0 4 4 4 0 MFS_1 like family NOA36 PF06524.7 KFM08230.1 - 5.1 6.2 8.6 8 5.6 6.0 1.2 1 0 0 1 1 1 0 NOA36 protein RasGAP PF00616.14 KFM08231.1 - 3.7e-46 157.2 2.9 5.1e-46 156.8 0.0 2.7 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 KFM08231.1 - 8.1e-42 142.2 13.8 8.1e-42 142.2 9.5 3.3 3 0 0 3 3 3 2 RasGAP C-terminus IQ PF00612.22 KFM08231.1 - 1.5e-19 67.6 9.5 8.6e-05 21.8 0.0 5.2 5 0 0 5 5 5 4 IQ calmodulin-binding motif CH PF00307.26 KFM08231.1 - 1.5e-11 44.3 0.0 7.6e-11 42.0 0.0 2.3 1 0 0 1 1 1 1 Calponin homology (CH) domain SHD1 PF03983.7 KFM08231.1 - 0.028 14.0 0.2 0.062 12.9 0.1 1.5 1 0 0 1 1 1 0 SLA1 homology domain 1, SHD1 7tm_1 PF00001.16 KFM08232.1 - 5.1e-40 137.2 40.4 3.9e-39 134.3 28.0 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PRRSV_2b PF07069.6 KFM08232.1 - 0.052 13.8 0.6 0.052 13.8 0.5 3.4 4 0 0 4 4 4 0 Porcine reproductive and respiratory syndrome virus 2b S_100 PF01023.14 KFM08233.1 - 4.6e-16 57.8 0.3 7e-16 57.2 0.2 1.3 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_1 PF00036.27 KFM08233.1 - 3.4e-05 22.8 0.2 7.5e-05 21.7 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 KFM08233.1 - 0.00028 20.9 0.3 0.00037 20.5 0.2 1.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 KFM08233.1 - 0.013 14.7 0.3 0.028 13.7 0.2 1.6 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 KFM08233.1 - 0.044 13.6 0.1 0.21 11.5 0.1 2.0 2 0 0 2 2 2 0 EF-hand domain CRF-BP PF05428.6 KFM08234.1 - 2.4e-143 476.6 0.0 2.8e-143 476.4 0.0 1.0 1 0 0 1 1 1 1 Corticotropin-releasing factor binding protein (CRF-BP) G-patch PF01585.18 KFM08235.1 - 1.4e-13 50.3 4.4 2.7e-13 49.4 3.1 1.5 1 0 0 1 1 1 1 G-patch domain FHA PF00498.21 KFM08235.1 - 2.6e-13 49.8 0.1 6.2e-13 48.6 0.1 1.7 1 0 0 1 1 1 1 FHA domain G-patch_2 PF12656.2 KFM08235.1 - 1.8e-06 27.6 0.4 1.8e-06 27.6 0.3 3.0 3 0 0 3 3 3 1 DExH-box splicing factor binding site WD40 PF00400.27 KFM08236.1 - 2.1e-23 81.2 13.5 1.7e-06 27.7 0.0 6.7 6 1 0 6 6 6 5 WD domain, G-beta repeat TBCA PF02970.11 KFM08238.1 - 3.2e-25 88.0 14.4 3.7e-25 87.8 10.0 1.0 1 0 0 1 1 1 1 Tubulin binding cofactor A Pkip-1 PF06878.6 KFM08238.1 - 0.03 14.2 4.2 0.042 13.7 2.9 1.2 1 0 0 1 1 1 0 Pkip-1 protein DUF3841 PF12952.2 KFM08238.1 - 0.052 12.9 1.5 0.06 12.8 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3841) Latarcin PF10279.4 KFM08238.1 - 0.32 11.1 3.6 0.52 10.5 2.5 1.4 1 1 0 1 1 1 0 Latarcin precursor LUC7 PF03194.10 KFM08238.1 - 0.33 10.4 6.3 0.44 10.0 4.4 1.1 1 0 0 1 1 1 0 LUC7 N_terminus Phage_GP20 PF06810.6 KFM08238.1 - 0.46 9.9 8.0 0.069 12.5 2.4 1.7 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF4208 PF13907.1 KFM08238.1 - 3.3 7.9 6.1 1 9.6 0.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4208) SCAMP PF04144.8 KFM08239.1 - 1.2e-74 249.9 13.8 1.6e-74 249.6 9.6 1.1 1 0 0 1 1 1 1 SCAMP family ABC2_membrane_5 PF13346.1 KFM08239.1 - 2 7.6 14.0 2.8 7.1 9.7 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein L_HGMIC_fpl PF10242.4 KFM08240.1 - 1.6e-64 217.2 8.3 1.8e-64 217.0 5.7 1.0 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.1 KFM08240.1 - 1.2e-10 41.4 1.8 1.7e-10 40.8 1.1 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Nucleos_tra2_C PF07662.8 KFM08240.1 - 7.4e-05 22.3 1.1 7.4e-05 22.3 0.7 1.7 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Claudin_3 PF06653.6 KFM08240.1 - 0.0072 16.0 5.0 0.0072 16.0 3.4 1.7 2 0 0 2 2 2 1 Tight junction protein, Claudin-like PMP22_Claudin PF00822.15 KFM08240.1 - 0.13 11.8 16.0 0.35 10.5 11.0 1.8 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family SUR7 PF06687.7 KFM08240.1 - 7.2 6.1 14.2 7.3 6.0 4.1 3.0 3 0 0 3 3 3 0 SUR7/PalI family Sulfatase PF00884.18 KFM08241.1 - 5.2e-48 163.8 0.0 9.7e-48 162.9 0.0 1.4 2 0 0 2 2 2 1 Sulfatase Phosphodiest PF01663.17 KFM08241.1 - 0.005 16.1 0.0 0.0056 16.0 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.7 KFM08241.1 - 0.0089 14.9 0.1 0.02 13.7 0.1 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1501) Sulfatase_C PF14707.1 KFM08241.1 - 0.012 15.8 0.4 0.035 14.3 0.3 1.9 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase PT-TG PF14449.1 KFM08241.1 - 0.081 12.7 1.1 0.16 11.7 0.3 1.8 2 0 0 2 2 2 0 Pre-toxin TG DAO PF01266.19 KFM08242.1 - 6.9e-76 255.4 0.0 1e-75 254.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T PF01571.16 KFM08242.1 - 1.2e-57 194.7 0.0 1.9e-57 194.0 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KFM08242.1 - 1.9e-22 79.0 0.0 4.1e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Pyr_redox_3 PF13738.1 KFM08242.1 - 3.2e-07 30.6 0.0 1.7e-06 28.2 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SoxG PF04268.7 KFM08242.1 - 6.9e-07 29.2 0.0 1.5e-06 28.1 0.0 1.6 1 1 0 1 1 1 1 Sarcosine oxidase, gamma subunit family NAD_binding_8 PF13450.1 KFM08242.1 - 2.1e-05 24.4 0.9 0.00019 21.3 0.5 2.5 1 1 1 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KFM08242.1 - 3.9e-05 22.6 0.2 7.5e-05 21.7 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KFM08242.1 - 0.00027 20.1 0.2 0.00056 19.0 0.2 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 KFM08242.1 - 0.0017 17.5 0.3 0.003 16.6 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KFM08242.1 - 0.0019 18.0 0.0 0.0034 17.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFM08242.1 - 0.011 16.1 0.2 0.025 14.9 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KFM08242.1 - 0.013 14.9 0.1 0.03 13.7 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 KFM08242.1 - 0.018 13.9 0.1 0.029 13.3 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 KFM08242.1 - 0.036 13.8 0.1 0.09 12.5 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Shikimate_DH PF01488.15 KFM08242.1 - 0.096 12.7 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 KFM08242.1 - 0.12 10.7 0.1 0.83 8.0 0.1 2.3 3 0 0 3 3 3 0 HI0933-like protein S-methyl_trans PF02574.11 KFM08243.1 - 1.9e-69 234.2 0.0 2.3e-69 234.0 0.0 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase WH2 PF02205.15 KFM08245.1 - 0.0018 17.8 0.3 0.0018 17.8 0.2 3.5 4 0 0 4 4 4 1 WH2 motif Rsc14 PF08586.5 KFM08245.1 - 1.9 9.0 11.2 1.6 9.2 2.8 3.2 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit WH1 PF00568.18 KFM08246.1 - 3.6e-35 120.0 0.4 6.8e-35 119.1 0.3 1.5 1 0 0 1 1 1 1 WH1 domain GAS PF13851.1 KFM08246.1 - 0.00052 19.2 48.3 0.0036 16.5 15.4 2.5 2 1 1 3 3 3 2 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.3 KFM08246.1 - 0.0012 18.6 19.4 0.0012 18.6 13.4 3.1 2 1 1 3 3 3 1 TATA element modulatory factor 1 TATA binding DUF4164 PF13747.1 KFM08246.1 - 0.0033 17.5 22.5 0.0088 16.1 8.8 3.4 2 1 2 4 4 4 1 Domain of unknown function (DUF4164) Atg14 PF10186.4 KFM08246.1 - 0.0062 15.5 18.6 0.012 14.5 12.9 1.6 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF445 PF04286.7 KFM08246.1 - 0.0083 15.6 13.7 0.013 15.1 9.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF445) Fib_alpha PF08702.5 KFM08246.1 - 0.0095 16.0 15.5 0.062 13.4 5.3 2.5 1 1 0 2 2 2 1 Fibrinogen alpha/beta chain family FUSC PF04632.7 KFM08246.1 - 0.015 13.7 3.6 0.02 13.3 2.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DMPK_coil PF08826.5 KFM08246.1 - 0.015 15.1 5.1 0.015 15.1 3.5 3.4 2 1 1 3 3 3 0 DMPK coiled coil domain like Reo_sigmaC PF04582.7 KFM08246.1 - 0.016 14.3 7.2 0.54 9.3 1.0 2.5 1 1 1 2 2 2 0 Reovirus sigma C capsid protein CENP-K PF11802.3 KFM08246.1 - 0.018 14.2 15.2 0.031 13.5 10.5 1.3 1 0 0 1 1 1 0 Centromere-associated protein K LuxC PF05893.9 KFM08246.1 - 0.028 13.1 1.5 0.045 12.4 1.1 1.5 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Nsp1_C PF05064.8 KFM08246.1 - 0.048 13.3 22.7 0.73 9.4 7.1 2.6 1 1 1 2 2 2 0 Nsp1-like C-terminal region ATG16 PF08614.6 KFM08246.1 - 0.055 13.3 35.8 0.28 10.9 4.8 3.2 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Laminin_II PF06009.7 KFM08246.1 - 0.091 12.5 19.2 0.021 14.5 5.4 2.9 2 1 1 3 3 3 0 Laminin Domain II DUF1664 PF07889.7 KFM08246.1 - 0.11 12.2 13.3 0.19 11.5 5.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) IncA PF04156.9 KFM08246.1 - 0.13 11.8 40.0 0.031 13.8 9.3 2.8 2 1 1 3 3 3 0 IncA protein DivIC PF04977.10 KFM08246.1 - 0.17 11.3 32.4 0.14 11.7 2.9 4.7 3 2 3 6 6 6 0 Septum formation initiator NPV_P10 PF05531.7 KFM08246.1 - 0.18 12.0 11.9 0.29 11.4 0.5 3.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Tropomyosin PF00261.15 KFM08246.1 - 0.22 10.5 28.5 0.0064 15.6 14.6 1.9 2 0 0 2 2 2 0 Tropomyosin Syntaxin-6_N PF09177.6 KFM08246.1 - 0.28 11.5 16.3 0.61 10.5 2.8 3.2 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DUF4140 PF13600.1 KFM08246.1 - 0.29 11.5 21.0 0.76 10.2 3.0 3.7 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) BLOC1_2 PF10046.4 KFM08246.1 - 0.64 10.1 26.4 0.19 11.8 5.8 3.6 2 1 2 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3461 PF11944.3 KFM08246.1 - 1.1 9.1 14.2 0.22 11.3 3.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3461) AAA_13 PF13166.1 KFM08246.1 - 1.5 7.1 26.6 0.23 9.8 15.1 1.8 1 1 0 1 1 1 0 AAA domain CENP-F_leu_zip PF10473.4 KFM08246.1 - 1.6 8.6 37.6 0.12 12.2 18.9 3.2 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 KFM08246.1 - 1.9 7.4 35.6 0.12 11.3 12.8 2.5 2 1 1 3 3 3 0 Autophagy protein Apg6 DUF4559 PF15112.1 KFM08246.1 - 2.2 7.3 21.4 0.54 9.3 9.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4559) TACC PF05010.9 KFM08246.1 - 2.2 7.9 25.2 0.67 9.6 13.4 2.5 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) TPR_MLP1_2 PF07926.7 KFM08246.1 - 2.3 7.9 32.8 12 5.6 4.2 3.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1465 PF07323.7 KFM08246.1 - 2.6 7.5 12.0 0.2 11.2 1.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) DUF342 PF03961.8 KFM08246.1 - 2.7 6.3 19.9 11 4.2 12.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF2968 PF11180.3 KFM08246.1 - 4.3 6.6 27.4 1.4 8.2 2.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2968) DUF3584 PF12128.3 KFM08246.1 - 4.9 4.3 30.5 0.38 8.0 8.1 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) DUF812 PF05667.6 KFM08246.1 - 6.4 5.1 26.9 11 4.3 18.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF812) COG2 PF06148.6 KFM08246.1 - 6.5 6.6 19.2 5.8 6.7 0.2 3.6 2 1 2 4 4 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Seryl_tRNA_N PF02403.17 KFM08246.1 - 6.7 6.7 28.4 0.075 13.0 6.6 3.0 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain ADIP PF11559.3 KFM08246.1 - 7.6 6.4 36.6 0.28 11.0 8.9 2.9 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.3 KFM08246.1 - 8.4 6.2 41.0 0.28 11.0 5.9 3.8 2 1 2 4 4 3 0 TATA element modulatory factor 1 DNA binding OTU PF02338.14 KFM08247.1 - 5.3e-29 101.2 0.0 1.5e-28 99.8 0.0 1.8 1 0 0 1 1 1 1 OTU-like cysteine protease UBA_4 PF14555.1 KFM08247.1 - 2.9e-05 23.5 0.0 5.3e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain zf-H2C2_2 PF13465.1 KFM08248.1 - 9.3e-14 50.9 10.4 1.2e-07 31.6 1.8 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFM08248.1 - 1.4e-13 50.3 23.2 0.0001 22.4 0.3 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM08248.1 - 6e-11 41.8 20.2 0.0002 21.4 0.7 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 KFM08248.1 - 0.0031 17.6 10.2 0.49 10.6 0.3 4.0 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-BED PF02892.10 KFM08248.1 - 0.037 13.7 14.8 0.12 12.0 2.2 2.9 2 1 1 3 3 3 0 BED zinc finger zf-Di19 PF05605.7 KFM08248.1 - 0.74 9.9 5.0 0.28 11.3 1.3 2.0 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Ion_trans PF00520.26 KFM08249.1 - 1.2e-10 40.9 13.8 7.9e-10 38.3 9.6 2.1 1 1 0 1 1 1 1 Ion transport protein VRR_NUC PF08774.6 KFM08250.1 - 6.1e-22 77.5 0.0 1.3e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 VRR-NUC domain zf-TRAF PF02176.13 KFM08250.1 - 0.0043 17.3 0.5 0.017 15.4 0.4 2.1 1 0 0 1 1 1 1 TRAF-type zinc finger PRP21_like_P PF12230.3 KFM08250.1 - 0.082 12.3 0.1 0.082 12.3 0.1 1.5 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein Mpp10 PF04006.7 KFM08251.1 - 4.5e-154 514.1 78.7 5.4e-154 513.8 54.5 1.1 1 0 0 1 1 1 1 Mpp10 protein Glyoxalase_4 PF13669.1 KFM08252.1 - 5.7e-23 81.0 0.0 6.9e-23 80.7 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KFM08252.1 - 6.5e-12 46.0 0.0 7.8e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KFM08252.1 - 2.3e-11 43.7 0.0 2.7e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 KFM08252.1 - 7.3e-09 35.7 0.0 8.9e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain PID PF00640.18 KFM08253.1 - 2.5e-50 170.0 2.5 2.5e-50 170.0 1.7 2.4 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) PDZ PF00595.19 KFM08253.1 - 3.3e-32 110.5 6.3 1.2e-15 57.3 0.6 2.7 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM08253.1 - 3.4e-06 26.8 0.0 0.00054 19.8 0.0 2.5 2 0 0 2 2 2 1 PDZ domain Phage_CP76 PF06892.6 KFM08253.1 - 0.0066 15.7 0.6 0.41 9.9 0.1 2.8 2 1 0 2 2 2 1 Phage regulatory protein CII (CP76) Tricorn_PDZ PF14685.1 KFM08253.1 - 0.092 12.5 0.3 2 8.2 0.0 2.4 2 0 0 2 2 2 0 Tricorn protease PDZ domain CD20 PF04103.10 KFM08254.1 - 8e-08 32.3 10.6 1.4e-07 31.5 7.3 1.4 1 0 0 1 1 1 1 CD20-like family PDZ PF00595.19 KFM08255.1 - 8.8e-50 166.8 7.2 4.7e-16 58.7 0.1 3.5 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) ZU5 PF00791.15 KFM08255.1 - 9.4e-36 121.6 0.0 2.5e-35 120.2 0.0 1.8 1 0 0 1 1 1 1 ZU5 domain PDZ_2 PF13180.1 KFM08255.1 - 7.9e-18 64.1 4.3 7.8e-06 25.6 0.1 3.6 3 0 0 3 3 3 3 PDZ domain Guanylate_kin PF00625.16 KFM08255.1 - 1.6e-11 43.9 0.0 3e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase SH3_2 PF07653.12 KFM08255.1 - 3.6e-11 42.3 0.1 9.9e-11 40.9 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM08255.1 - 0.0016 17.7 0.1 0.014 14.7 0.0 2.6 2 0 0 2 2 2 1 SH3 domain DUF104 PF01954.11 KFM08255.1 - 0.12 12.4 1.9 2.3 8.3 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function DUF104 tRNA-synt_2b PF00587.20 KFM08256.1 - 6.3e-44 149.5 0.3 1.1e-43 148.8 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KFM08256.1 - 2.7e-20 72.1 0.1 6.7e-20 70.8 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 KFM08256.1 - 9e-14 51.0 0.0 2.1e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 KFM08256.1 - 1.1e-12 47.5 0.0 2.2e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 TGS domain TM2 PF05154.11 KFM08257.1 - 1.8e-14 53.6 8.3 2.6e-14 53.1 5.8 1.3 1 0 0 1 1 1 1 TM2 domain A_deaminase PF00962.17 KFM08258.1 - 4.3e-45 154.0 0.0 4.9e-45 153.8 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase La PF05383.12 KFM08259.1 - 1.2e-22 79.4 0.2 2.7e-22 78.3 0.2 1.6 1 0 0 1 1 1 1 La domain DUF2186 PF09952.4 KFM08259.1 - 0.11 12.7 0.2 0.17 12.1 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2186) LRR_4 PF12799.2 KFM08260.1 - 1.2e-26 91.8 32.6 1.8e-08 33.8 4.0 5.3 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 KFM08260.1 - 8e-18 64.6 12.0 1.2e-10 41.1 1.2 3.5 2 1 1 3 3 3 3 Leucine-rich repeat LRR_8 PF13855.1 KFM08260.1 - 5.8e-16 57.9 41.2 5.2e-08 32.5 7.1 5.9 4 1 1 7 7 7 4 Leucine rich repeat LRR_1 PF00560.28 KFM08260.1 - 1e-06 27.9 38.4 0.31 11.2 0.2 8.6 8 1 0 8 8 8 6 Leucine Rich Repeat LRR_6 PF13516.1 KFM08260.1 - 5.9e-05 22.7 23.5 1.7 8.9 0.3 8.0 4 1 4 8 8 8 4 Leucine Rich repeat LRR_7 PF13504.1 KFM08260.1 - 0.00011 21.7 20.9 1.1 9.8 0.1 8.2 5 2 2 7 7 7 2 Leucine rich repeat DUF2322 PF10084.4 KFM08260.1 - 0.29 10.9 3.5 1.8 8.3 0.2 3.3 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2322) MUG2_C PF08593.5 KFM08260.1 - 1.7 8.9 6.2 22 5.3 0.1 4.2 4 0 0 4 4 4 0 Meiotically up-regulated glycoproteins C-terminal ADAM_spacer1 PF05986.9 KFM08261.1 - 2.6e-36 123.9 0.0 3.8e-36 123.3 0.0 1.2 1 0 0 1 1 1 1 ADAM-TS Spacer 1 TSP_1 PF00090.14 KFM08261.1 - 1.7e-27 95.2 75.6 7.3e-08 32.4 3.8 6.9 5 1 1 6 6 6 6 Thrombospondin type 1 domain PLAC PF08686.6 KFM08261.1 - 1.7e-10 41.0 14.1 1.7e-10 41.0 9.8 2.6 2 0 0 2 2 2 1 PLAC (protease and lacunin) domain Neur_chan_LBD PF02931.18 KFM08262.1 - 1.9e-71 239.6 1.1 2.5e-71 239.2 0.8 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFM08262.1 - 9.6e-63 212.2 0.0 1.2e-62 211.9 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region AHS1 PF02682.11 KFM08263.1 - 0.25 10.7 5.3 2.8 7.3 1.0 2.6 1 1 1 2 2 2 0 Allophanate hydrolase subunit 1 Baculo_PEP_C PF04513.7 KFM08263.1 - 0.28 11.0 21.2 0.63 9.8 0.5 4.1 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cytochrom_C_2 PF01322.15 KFM08263.1 - 4.9 7.7 8.4 21 5.6 0.1 2.6 1 1 0 2 2 2 0 Cytochrome C' Myosin_head PF00063.16 KFM08264.1 - 1.3e-223 743.9 5.1 2.3e-223 743.1 3.5 1.4 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 KFM08264.1 - 5e-64 215.2 0.6 9e-64 214.4 0.4 1.4 1 0 0 1 1 1 1 Myosin tail SH3_1 PF00018.23 KFM08264.1 - 2.8e-17 61.8 0.4 1.1e-16 59.9 0.1 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KFM08264.1 - 2.5e-16 59.0 0.1 6.1e-16 57.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFM08264.1 - 5.7e-12 44.9 0.0 1.6e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain IQ PF00612.22 KFM08264.1 - 0.0082 15.6 3.1 0.023 14.2 2.2 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif Cyclin_N PF00134.18 KFM08265.1 - 1.4e-44 150.7 0.4 7.7e-44 148.3 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFM08265.1 - 1e-33 115.7 0.6 2.2e-33 114.6 0.4 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain RNF111_N PF15303.1 KFM08266.1 - 5.6e-108 360.5 25.6 5.6e-108 360.5 17.7 2.5 2 1 0 2 2 2 1 E3 ubiquitin-protein ligase Arkadia N-terminus zf-RING_2 PF13639.1 KFM08266.1 - 7.3e-15 54.5 6.2 7.3e-15 54.5 4.3 3.5 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFM08266.1 - 5.3e-08 32.4 3.9 5.3e-08 32.4 2.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM08266.1 - 2e-07 30.8 6.7 2e-07 30.8 4.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFM08266.1 - 6.8e-07 29.3 5.2 6.8e-07 29.3 3.6 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KFM08266.1 - 1.5e-06 27.7 5.9 1.5e-06 27.7 4.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM08266.1 - 4.9e-06 26.1 3.9 4.9e-06 26.1 2.7 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 KFM08266.1 - 0.055 13.3 5.8 0.11 12.2 2.7 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger RRM_1 PF00076.17 KFM08267.1 - 1.2e-11 44.1 0.0 2.6e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM08267.1 - 3.7e-11 42.8 0.0 1.3e-10 41.1 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM08267.1 - 1.9e-05 24.4 0.0 3.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF544 PF04424.8 KFM08268.1 - 1e-48 164.1 1.3 1.1e-48 163.9 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF544) CCDC50_N PF15295.1 KFM08268.1 - 0.24 11.3 9.7 0.62 9.9 6.7 1.8 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus Reprolysin_2 PF13574.1 KFM08269.1 - 1.6e-32 112.9 0.4 3.2e-32 111.9 0.3 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KFM08269.1 - 5.3e-32 111.3 1.5 2.2e-31 109.3 0.1 2.3 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KFM08269.1 - 1.5e-26 93.2 0.6 2.3e-26 92.6 0.4 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KFM08269.1 - 7.8e-22 78.1 0.0 2.1e-21 76.6 0.0 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.14 KFM08269.1 - 9.2e-17 61.0 0.4 1.6e-16 60.2 0.3 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide Disintegrin PF00200.18 KFM08269.1 - 1.5e-15 57.1 31.5 1.5e-15 57.1 21.8 3.2 2 1 1 3 3 3 1 Disintegrin Reprolysin PF01421.14 KFM08269.1 - 1.2e-08 34.7 0.3 2.6e-07 30.4 0.2 2.7 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease UPF0370 PF13980.1 KFM08269.1 - 0.0011 18.7 0.4 0.0025 17.5 0.3 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0370) Lipase PF00151.14 KFM08270.1 - 3.9e-108 361.5 0.0 4.6e-108 361.3 0.0 1.0 1 0 0 1 1 1 1 Lipase PLAT PF01477.18 KFM08270.1 - 2.4e-16 60.0 1.5 5e-16 59.0 1.1 1.6 1 0 0 1 1 1 1 PLAT/LH2 domain Abhydrolase_6 PF12697.2 KFM08270.1 - 7.2e-06 26.0 0.1 8.7e-06 25.7 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family MIP PF00230.15 KFM08271.1 - 5.9e-52 176.3 13.8 7.2e-52 176.0 9.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF4401 PF14351.1 KFM08271.1 - 0.037 13.0 11.8 0.14 11.1 8.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4401) Aldedh PF00171.17 KFM08272.1 - 2.7e-182 606.2 0.0 3e-182 606.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KFM08272.1 - 0.0073 15.0 0.1 0.11 11.1 0.0 2.0 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 KFM08272.1 - 0.011 14.9 0.1 3.3 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Ldh_2 PF02615.9 KFM08272.1 - 0.11 11.1 0.0 0.21 10.2 0.0 1.4 1 0 0 1 1 1 0 Malate/L-lactate dehydrogenase GCOM2 PF15328.1 KFM08273.1 - 2.9e-72 243.0 41.3 2.9e-72 243.0 28.6 1.8 2 0 0 2 2 2 1 Putative GRINL1B complex locus protein 2 SlyX PF04102.7 KFM08273.1 - 0.019 15.3 2.6 0.019 15.3 1.8 6.4 3 2 3 7 7 7 0 SlyX Reo_sigmaC PF04582.7 KFM08273.1 - 0.085 12.0 13.8 0.17 11.0 3.3 2.8 2 1 0 2 2 2 0 Reovirus sigma C capsid protein HMA PF00403.21 KFM08273.1 - 0.12 12.5 3.7 0.31 11.2 0.0 3.4 3 0 0 3 3 3 0 Heavy-metal-associated domain DUF869 PF05911.6 KFM08273.1 - 0.2 9.8 56.7 0.44 8.7 14.2 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) Myosin_tail_1 PF01576.14 KFM08274.1 - 7.9e-44 149.6 180.8 2.2e-27 95.2 32.7 3.9 1 1 2 3 3 3 3 Myosin tail ERM PF00769.14 KFM08274.1 - 0.00021 20.9 35.7 0.00021 20.9 24.8 6.5 3 1 3 6 6 6 2 Ezrin/radixin/moesin family GAS PF13851.1 KFM08274.1 - 0.0011 18.1 32.9 0.0011 18.1 22.8 7.6 1 1 6 7 7 7 1 Growth-arrest specific micro-tubule binding DUF4164 PF13747.1 KFM08274.1 - 0.0043 17.1 11.0 0.0043 17.1 7.6 9.9 1 1 6 9 9 9 3 Domain of unknown function (DUF4164) Reo_sigmaC PF04582.7 KFM08274.1 - 0.0062 15.7 49.1 0.031 13.4 1.3 6.3 1 1 5 6 6 6 5 Reovirus sigma C capsid protein Filament PF00038.16 KFM08274.1 - 0.011 15.2 155.2 0.19 11.1 45.3 6.4 1 1 5 6 6 6 0 Intermediate filament protein MtrB PF05440.7 KFM08274.1 - 9.4 6.3 8.5 10 6.2 0.2 4.3 3 2 1 4 4 4 0 Tetrahydromethanopterin S-methyltransferase subunit B DUF4195 PF13836.1 KFM08275.1 - 6.2e-33 114.0 19.9 6.2e-33 114.0 13.8 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4195) zf-H2C2_5 PF13909.1 KFM08275.1 - 0.0023 18.0 0.7 0.0023 18.0 0.5 8.2 9 1 0 9 9 9 3 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 KFM08275.1 - 0.0037 17.4 0.1 0.0037 17.4 0.1 10.4 11 2 1 12 12 12 3 Zinc-finger double domain zf-C2H2_6 PF13912.1 KFM08275.1 - 0.0059 16.4 0.1 0.0059 16.4 0.0 7.9 8 2 0 8 8 8 2 C2H2-type zinc finger zf-Di19 PF05605.7 KFM08275.1 - 0.0076 16.3 2.0 0.0076 16.3 1.4 7.2 6 2 1 7 7 7 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 KFM08275.1 - 0.018 15.1 0.1 0.018 15.1 0.1 7.2 6 1 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KFM08275.1 - 0.066 13.5 0.7 0.066 13.5 0.5 9.1 8 0 0 8 8 8 0 C2H2-type zinc finger zf-met PF12874.2 KFM08275.1 - 0.14 12.4 0.2 0.14 12.4 0.2 6.7 6 1 0 6 6 6 0 Zinc-finger of C2H2 type RasGAP PF00616.14 KFM08276.1 - 1.7e-50 171.4 0.7 4.5e-50 170.0 0.0 2.2 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 KFM08276.1 - 5.7e-41 139.5 12.5 1.1e-39 135.3 8.0 3.9 4 0 0 4 4 4 2 RasGAP C-terminus IQ PF00612.22 KFM08276.1 - 8.3e-19 65.3 20.1 1.1e-05 24.6 0.4 5.3 5 0 0 5 5 5 4 IQ calmodulin-binding motif CH PF00307.26 KFM08276.1 - 1.2e-14 54.2 0.0 6.4e-14 51.8 0.0 2.4 1 0 0 1 1 1 1 Calponin homology (CH) domain WW PF00397.21 KFM08276.1 - 0.066 13.0 4.9 0.13 12.1 3.4 1.5 1 0 0 1 1 1 0 WW domain Nif11 PF07862.6 KFM08276.1 - 0.1 12.5 1.7 0.74 9.7 0.1 3.2 2 0 0 2 2 2 0 Nitrogen fixation protein of unknown function Spc97_Spc98 PF04130.8 KFM08277.1 - 7.1e-107 357.9 10.1 1.1e-106 357.3 7.0 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF383 PF04063.9 KFM08277.1 - 0.053 13.0 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF383) His_Phos_2 PF00328.17 KFM08280.1 - 8.6e-110 367.3 0.3 1.1e-109 366.9 0.2 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 KFM08280.1 - 0.0059 16.0 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain His_Phos_1 PF00300.17 KFM08280.1 - 0.0096 16.0 0.0 0.036 14.1 0.0 2.0 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) ATP-gua_Ptrans PF00217.14 KFM08281.1 - 3.8e-103 344.0 0.0 4.5e-103 343.7 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 KFM08281.1 - 7.4e-35 118.9 0.0 1.2e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain Thioredoxin PF00085.15 KFM08282.1 - 1.5e-45 153.1 0.0 3.8e-32 110.0 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 KFM08282.1 - 1.7e-41 142.0 0.2 2.4e-36 125.2 0.1 3.0 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 KFM08282.1 - 3.8e-10 39.9 0.1 2.1e-06 27.8 0.1 3.8 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KFM08282.1 - 5.3e-06 26.4 0.1 0.00092 19.2 0.0 3.6 4 0 0 4 4 4 1 Thioredoxin-like Thioredoxin_7 PF13899.1 KFM08282.1 - 7.7e-05 22.6 0.0 0.00021 21.2 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like Calsequestrin PF01216.12 KFM08282.1 - 0.0013 17.5 0.1 0.0042 15.9 0.0 1.8 1 1 1 2 2 2 1 Calsequestrin Thioredoxin_4 PF13462.1 KFM08282.1 - 0.0023 17.9 0.1 0.16 11.9 0.0 3.1 3 0 0 3 3 3 1 Thioredoxin AhpC-TSA PF00578.16 KFM08282.1 - 0.041 13.5 0.1 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 AhpC/TSA family CaM_bdg_C0 PF10562.4 KFM08283.1 - 1.2 9.0 3.3 13 5.7 0.1 2.4 2 1 0 2 2 2 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit Prp19_bind PF06991.6 KFM08284.1 - 3.5e-130 433.2 36.9 3.5e-130 433.2 25.6 2.2 1 1 1 2 2 2 1 Splicing factor, Prp19-binding domain Peptidase_S8 PF00082.17 KFM08285.1 - 5.1e-48 163.6 5.9 8.4e-48 162.9 4.1 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 KFM08285.1 - 1.1e-30 105.2 0.0 2e-30 104.3 0.0 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain DUF357 PF04010.8 KFM08285.1 - 0.07 12.8 0.2 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF357) Glyco_hydro_38 PF01074.17 KFM08286.1 - 5.1e-97 324.4 0.7 7.9e-97 323.7 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 KFM08286.1 - 9.3e-75 252.1 0.0 1.2e-74 251.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 KFM08286.1 - 8.2e-22 77.2 0.0 1.8e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase, middle domain UNC45-central PF11701.3 KFM08287.1 - 1e-42 145.4 15.8 2e-40 138.0 0.1 4.9 4 1 1 5 5 5 2 Myosin-binding striated muscle assembly central TPR_11 PF13414.1 KFM08287.1 - 7.5e-17 60.7 15.8 2.8e-10 39.6 5.4 2.7 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 KFM08287.1 - 1.1e-12 46.9 5.0 5.1e-05 22.7 0.8 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFM08287.1 - 5.4e-11 41.5 11.3 0.00012 21.7 0.0 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFM08287.1 - 3.9e-08 32.5 4.3 0.0012 18.4 0.0 4.0 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFM08287.1 - 1e-06 28.5 8.9 0.0011 18.8 4.7 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 KFM08287.1 - 1.8e-06 27.6 8.6 0.0098 15.7 3.3 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat HEAT_2 PF13646.1 KFM08287.1 - 3.2e-06 27.3 14.1 0.13 12.5 0.0 7.1 4 3 4 8 8 8 2 HEAT repeats TPR_17 PF13431.1 KFM08287.1 - 4.4e-06 26.4 1.1 0.12 12.6 0.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFM08287.1 - 0.00061 20.4 3.2 0.00061 20.4 2.2 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 KFM08287.1 - 0.00082 19.4 4.2 0.00082 19.4 2.9 2.4 3 0 0 3 3 1 1 Anaphase-promoting complex, cyclosome, subunit 3 Arm PF00514.18 KFM08287.1 - 0.0023 17.7 7.8 13 5.7 0.0 7.6 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat TPR_6 PF13174.1 KFM08287.1 - 0.008 16.5 5.0 0.19 12.2 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFM08287.1 - 0.014 15.7 10.5 0.11 12.8 4.3 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFM08287.1 - 0.031 14.8 0.2 0.031 14.8 0.1 4.8 3 1 2 5 5 3 0 Tetratricopeptide repeat Fis1_TPR_N PF14852.1 KFM08287.1 - 0.035 13.4 0.1 21 4.4 0.0 4.0 4 0 0 4 4 4 0 Fis1 N-terminal tetratricopeptide repeat DUF3587 PF12132.3 KFM08287.1 - 0.081 12.1 0.1 0.17 11.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3587) TPR_7 PF13176.1 KFM08287.1 - 0.28 11.0 5.0 21 5.2 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat RCC1 PF00415.13 KFM08288.1 - 1.5e-09 37.8 0.0 1.8e-09 37.6 0.0 1.0 1 0 0 1 1 1 1 Regulator of chromosome condensation (RCC1) repeat MAP65_ASE1 PF03999.7 KFM08289.1 - 4.2e-133 445.1 24.9 5.4e-133 444.8 17.3 1.0 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) DinI PF06183.8 KFM08289.1 - 0.24 11.4 0.1 0.24 11.4 0.1 3.7 4 0 0 4 4 4 0 DinI-like family DUF4407 PF14362.1 KFM08289.1 - 3 6.7 7.3 2.8 6.8 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Sec1 PF00995.18 KFM08290.1 - 2.5e-90 303.7 0.0 3.1e-90 303.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family TTL PF03133.10 KFM08291.1 - 3.8e-88 295.2 0.8 8.2e-88 294.1 0.6 1.5 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 KFM08291.1 - 1.3e-06 27.3 0.2 9.9e-05 21.2 0.0 3.0 2 1 1 3 3 3 1 YheC/D like ATP-grasp ATP-grasp_3 PF02655.9 KFM08291.1 - 0.016 15.0 0.0 0.09 12.6 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KFM08291.1 - 0.14 11.5 0.0 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus EF-hand_1 PF00036.27 KFM08292.1 - 7.6e-13 46.7 6.7 2.4e-05 23.3 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 KFM08292.1 - 2.5e-12 46.7 6.0 6.9e-11 42.1 1.5 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KFM08292.1 - 1.6e-11 43.0 4.4 6.6e-05 22.4 0.4 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.1 KFM08292.1 - 1.1e-10 40.3 3.4 9.7e-06 24.6 0.6 2.8 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 KFM08292.1 - 5.7e-09 35.4 5.9 0.00089 18.8 0.1 2.5 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFM08292.1 - 8.3e-06 25.8 0.3 2.6e-05 24.2 0.1 1.7 1 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFM08292.1 - 0.002 17.8 3.8 0.089 12.5 0.1 2.5 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Gal4_dimer PF03902.8 KFM08292.1 - 0.011 15.6 1.6 0.028 14.3 0.1 2.1 1 1 1 2 2 2 0 Gal4-like dimerisation domain EF-hand_9 PF14658.1 KFM08292.1 - 0.031 14.1 0.1 1.5 8.7 0.0 2.8 2 1 0 2 2 2 0 EF-hand domain EF-hand_10 PF14788.1 KFM08292.1 - 0.87 9.3 3.8 4.8 6.9 0.3 2.8 2 2 0 2 2 2 0 EF hand DUF3944 PF13099.1 KFM08292.1 - 2 7.9 4.9 0.34 10.4 0.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3944) Iso_dh PF00180.15 KFM08293.1 - 3.2e-75 253.2 0.0 3.8e-75 253.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Clat_adaptor_s PF01217.15 KFM08294.1 - 2.5e-40 137.4 3.1 4.1e-39 133.5 2.1 2.0 1 1 0 1 1 1 1 Clathrin adaptor complex small chain ERAP1_C PF11838.3 KFM08295.1 - 5.9e-32 111.2 0.0 8.4e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.15 KFM08295.1 - 3.1e-05 23.2 0.0 6.3e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M1 BpuSI_N PF15516.1 KFM08295.1 - 0.046 13.4 0.0 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 BpuSI N-terminal domain RQC PF09382.5 KFM08295.1 - 0.15 11.8 0.3 3.1 7.5 0.0 2.5 3 0 0 3 3 3 0 RQC domain 7tm_1 PF00001.16 KFM08296.1 - 1.9e-48 164.8 13.4 2.3e-48 164.5 9.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM08296.1 - 0.0025 17.0 5.5 0.0035 16.5 3.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx EMP24_GP25L PF01105.19 KFM08297.1 - 1e-28 100.2 0.0 1.2e-28 100.1 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD GOLD_2 PF13897.1 KFM08297.1 - 0.033 14.4 0.2 0.059 13.6 0.1 1.4 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Ank_2 PF12796.2 KFM08298.1 - 2.5e-36 123.8 5.5 1.1e-18 67.3 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFM08298.1 - 4.4e-19 67.2 1.8 8.3e-07 28.5 0.1 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 KFM08298.1 - 3.2e-15 56.1 0.5 1.8e-05 25.0 0.0 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM08298.1 - 3.6e-14 51.4 0.3 0.00014 21.7 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 KFM08298.1 - 2.6e-13 49.7 2.2 1.1e-07 31.8 0.1 4.3 3 2 2 5 5 5 4 Ankyrin repeats (many copies) NAD_binding_10 PF13460.1 KFM08298.1 - 0.044 13.7 0.0 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 NADH(P)-binding FMN_dh PF01070.13 KFM08298.1 - 0.062 12.1 0.0 0.093 11.5 0.0 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase RasGEF PF00617.14 KFM08299.1 - 5.9e-59 198.9 0.5 1.8e-58 197.3 0.4 1.9 1 0 0 1 1 1 1 RasGEF domain RhoGEF PF00621.15 KFM08299.1 - 6.4e-28 97.8 0.4 6.4e-28 97.8 0.3 2.3 3 0 0 3 3 3 1 RhoGEF domain RasGEF_N PF00618.15 KFM08299.1 - 8e-24 83.7 0.4 9.6e-17 60.9 0.1 3.7 3 0 0 3 3 3 2 RasGEF N-terminal motif PH PF00169.24 KFM08299.1 - 0.00048 20.2 0.1 0.017 15.3 0.1 2.8 3 0 0 3 3 3 1 PH domain IQ PF00612.22 KFM08299.1 - 0.0062 16.0 1.4 0.016 14.7 1.0 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif Peptidase_C1 PF00112.18 KFM08300.1 - 1.9e-79 266.5 0.8 2.2e-79 266.4 0.6 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 KFM08300.1 - 2.3e-05 23.1 0.6 0.0049 15.4 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family RQC PF09382.5 KFM08301.1 - 7.4e-27 93.1 0.1 1.4e-26 92.2 0.1 1.5 1 0 0 1 1 1 1 RQC domain BDHCT PF08072.6 KFM08301.1 - 1.4e-23 82.6 2.8 3.1e-23 81.5 2.0 1.6 1 0 0 1 1 1 1 BDHCT (NUC031) domain DEAD PF00270.24 KFM08301.1 - 2.1e-19 69.6 0.0 4.6e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFM08301.1 - 7.3e-16 57.7 0.0 2.3e-15 56.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HRDC PF00570.18 KFM08301.1 - 3.2e-12 45.9 0.0 7.6e-12 44.7 0.0 1.7 1 0 0 1 1 1 1 HRDC domain SNF2_N PF00176.18 KFM08301.1 - 0.00055 18.8 0.0 0.00089 18.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain FERM_N PF09379.5 KFM08302.1 - 7.8e-17 61.1 0.0 1.5e-15 56.9 0.1 2.4 2 0 0 2 2 2 1 FERM N-terminal domain FA PF08736.6 KFM08302.1 - 2.5e-16 59.2 0.3 6.8e-16 57.7 0.2 1.8 1 0 0 1 1 1 1 FERM adjacent (FA) FERM_C PF09380.5 KFM08302.1 - 1.2e-14 54.2 0.3 2.3e-14 53.3 0.2 1.4 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.13 KFM08302.1 - 2.8e-12 46.9 0.0 7.2e-08 32.6 0.0 2.4 2 0 0 2 2 2 2 FERM central domain YcxB PF14317.1 KFM08302.1 - 0.0014 17.8 0.2 0.0031 16.7 0.1 1.6 1 0 0 1 1 1 1 YcxB-like protein Gag_p30 PF02093.11 KFM08303.1 - 6.8e-31 107.1 0.4 7.8e-31 106.9 0.3 1.0 1 0 0 1 1 1 1 Gag P30 core shell protein Gag_p24 PF00607.15 KFM08303.1 - 0.00014 21.4 0.3 0.00018 21.1 0.2 1.2 1 1 0 1 1 1 1 gag gene protein p24 (core nucleocapsid protein) DUF3287 PF11690.3 KFM08303.1 - 0.0097 15.9 0.8 0.018 15.1 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3287) SCAN PF02023.12 KFM08303.1 - 0.081 12.3 1.8 0.12 11.8 1.3 1.3 1 0 0 1 1 1 0 SCAN domain Myosin_tail_1 PF01576.14 KFM08304.1 - 0.011 13.5 31.0 0.063 10.9 5.3 2.3 1 1 1 2 2 2 0 Myosin tail IncA PF04156.9 KFM08304.1 - 0.54 9.8 32.1 5.1 6.6 19.0 2.5 2 1 0 2 2 2 0 IncA protein Atg14 PF10186.4 KFM08304.1 - 0.86 8.4 27.7 2.9 6.7 9.7 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 HlyD PF00529.15 KFM08304.1 - 2.1 7.5 20.4 3.5 6.8 14.1 1.3 1 0 0 1 1 1 0 HlyD family secretion protein MerR-DNA-bind PF09278.6 KFM08304.1 - 4.4 7.7 11.3 12 6.3 0.3 3.6 2 1 1 3 3 3 0 MerR, DNA binding NIF PF03031.13 KFM08305.1 - 8.7e-55 184.7 1.3 1.8e-54 183.6 0.9 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase eIF3_subunit PF08597.5 KFM08306.1 - 1.2e-61 208.4 25.1 1.3e-61 208.2 17.4 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit BRICHOS PF04089.9 KFM08306.1 - 0.12 12.2 0.1 0.12 12.2 0.1 2.4 1 1 1 2 2 2 0 BRICHOS domain MscL PF01741.13 KFM08306.1 - 5 7.2 7.3 28 4.8 0.0 2.4 2 1 0 2 2 2 0 Large-conductance mechanosensitive channel, MscL DUF59 PF01883.14 KFM08307.1 - 0.00019 21.3 0.0 0.00034 20.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF59 ADAM_spacer1 PF05986.9 KFM08308.1 - 2.1e-33 114.5 0.0 3.9e-33 113.6 0.0 1.5 1 0 0 1 1 1 1 ADAM-TS Spacer 1 TSP_1 PF00090.14 KFM08308.1 - 2.4e-32 110.8 121.3 1.5e-08 34.6 5.4 10.1 10 0 0 10 10 10 8 Thrombospondin type 1 domain Reprolysin PF01421.14 KFM08308.1 - 4.1e-29 101.6 0.0 7.8e-29 100.6 0.0 1.5 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.14 KFM08308.1 - 5.9e-23 81.0 0.0 1e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_5 PF13688.1 KFM08308.1 - 8.4e-14 51.9 0.1 1.9e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KFM08308.1 - 1.8e-10 41.4 0.7 3.8e-10 40.3 0.1 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFM08308.1 - 2.7e-10 40.5 0.0 5.3e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFM08308.1 - 2.7e-08 33.6 0.0 4.5e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KFM08308.1 - 0.069 12.8 0.2 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 Matrixin SAM_decarbox PF01536.11 KFM08308.1 - 0.31 9.6 0.6 0.56 8.8 0.4 1.3 1 0 0 1 1 1 0 Adenosylmethionine decarboxylase MRG PF05712.8 KFM08309.1 - 1.5e-56 190.4 0.2 2.3e-56 189.7 0.1 1.3 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 KFM08309.1 - 5.5e-09 35.6 2.8 3.6e-07 29.7 0.1 2.7 2 0 0 2 2 2 2 RNA binding activity-knot of a chromodomain Neur_chan_memb PF02932.11 KFM08309.1 - 0.2 11.5 0.7 0.26 11.1 0.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Kinesin PF00225.18 KFM08310.1 - 4.3e-101 337.9 1.1 8.7e-101 336.9 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain ADIP PF11559.3 KFM08310.1 - 0.025 14.4 17.1 0.042 13.7 10.7 2.2 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Tnp_P_element PF12017.3 KFM08310.1 - 0.09 11.9 7.1 0.057 12.6 2.5 2.2 1 1 1 2 2 2 0 Transposase protein IncA PF04156.9 KFM08310.1 - 0.61 9.6 17.4 1.4 8.5 12.0 1.6 1 0 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 KFM08310.1 - 0.73 9.6 25.7 0.02 14.7 12.3 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF45 PF01863.12 KFM08310.1 - 1 9.1 10.9 2.3 7.9 7.5 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF45 FlxA PF14282.1 KFM08310.1 - 3.8 7.4 13.7 2.4 8.1 7.8 1.8 1 1 0 1 1 1 0 FlxA-like protein XhlA PF10779.4 KFM08310.1 - 5.7 6.9 10.7 1.7 8.6 4.8 2.2 1 1 1 2 2 2 0 Haemolysin XhlA HlyIII PF03006.15 KFM08311.1 - 1.8e-34 119.1 16.3 1.8e-34 119.1 11.3 1.4 2 0 0 2 2 2 1 Haemolysin-III related C5-epim_C PF06662.8 KFM08312.1 - 1.8e-76 255.6 0.1 3e-76 254.9 0.0 1.3 1 0 0 1 1 1 1 D-glucuronyl C5-epimerase C-terminus NAD_binding_6 PF08030.7 KFM08313.1 - 6.1e-31 107.4 0.0 9.4e-31 106.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KFM08313.1 - 1.3e-19 70.0 0.0 2.5e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain EF-hand_1 PF00036.27 KFM08313.1 - 1.7e-18 64.4 1.8 3.8e-06 25.8 0.0 5.4 5 0 0 5 5 5 3 EF hand Ferric_reduct PF01794.14 KFM08313.1 - 6.1e-17 61.8 7.2 1.5e-16 60.6 5.0 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component EF-hand_6 PF13405.1 KFM08313.1 - 2.8e-16 57.8 6.7 5.1e-06 25.9 0.1 5.6 5 0 0 5 5 5 3 EF-hand domain EF-hand_7 PF13499.1 KFM08313.1 - 8.8e-14 51.4 1.0 6.5e-06 26.1 0.4 3.2 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KFM08313.1 - 1.4e-12 46.3 9.4 0.00013 21.0 0.1 4.9 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 KFM08313.1 - 3.7e-08 32.8 4.5 0.00041 19.9 0.7 3.6 2 2 1 3 3 3 3 EF-hand domain pair FAD_binding_6 PF00970.19 KFM08313.1 - 0.00049 20.1 0.0 0.0014 18.7 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KFM08313.1 - 0.0058 17.1 0.1 0.32 11.5 0.0 2.7 1 1 0 2 2 2 1 Oxidoreductase NAD-binding domain LRR_4 PF12799.2 KFM08314.1 - 1.8e-14 52.9 19.3 1.4e-09 37.3 4.5 3.5 2 2 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM08314.1 - 4.8e-14 51.8 15.5 4.6e-09 35.9 3.2 2.8 1 1 2 3 3 3 3 Leucine rich repeat LRR_9 PF14580.1 KFM08314.1 - 8e-13 48.3 0.3 9e-13 48.1 0.2 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.1 KFM08314.1 - 1.2e-08 34.1 13.6 3e-05 23.6 0.2 4.6 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.28 KFM08314.1 - 4.3e-08 32.0 7.4 0.0083 16.0 0.1 4.7 4 1 0 4 4 4 3 Leucine Rich Repeat LRR_7 PF13504.1 KFM08314.1 - 7.9e-08 31.2 11.8 0.074 13.2 0.1 5.3 6 0 0 6 6 6 3 Leucine rich repeat LRR_2 PF07723.8 KFM08314.1 - 0.55 10.8 5.9 10 6.8 0.1 3.9 4 0 0 4 4 4 0 Leucine Rich Repeat Integrin_alpha2 PF08441.7 KFM08315.1 - 3.3e-89 299.8 0.5 5.2e-89 299.1 0.4 1.3 1 0 0 1 1 1 1 Integrin alpha VWA PF00092.23 KFM08315.1 - 1.8e-39 135.2 0.2 3.1e-39 134.5 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain FG-GAP PF01839.18 KFM08315.1 - 3.5e-13 48.8 6.0 9.9e-05 21.9 0.2 3.7 3 0 0 3 3 3 3 FG-GAP repeat VWA_2 PF13519.1 KFM08315.1 - 5.5e-12 46.1 0.0 9.7e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VCBS PF13517.1 KFM08315.1 - 3.8e-08 33.5 0.5 4.1e-05 23.8 0.1 3.0 2 0 0 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.1 KFM08315.1 - 7.4e-05 22.6 11.4 0.38 10.7 0.0 5.2 5 0 0 5 5 5 2 FG-GAP repeat vWA-TerF-like PF10138.4 KFM08315.1 - 0.035 13.9 0.1 0.082 12.7 0.1 1.6 1 0 0 1 1 1 0 vWA found in TerF C terminus Ank_2 PF12796.2 KFM08316.1 - 1.4e-62 208.0 17.6 4.3e-21 75.0 1.0 6.3 2 2 3 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 KFM08316.1 - 2.4e-55 181.7 18.4 1.6e-09 37.1 0.1 8.6 8 0 0 8 8 8 8 Ankyrin repeat Ank_4 PF13637.1 KFM08316.1 - 1e-39 134.1 8.7 6.2e-13 48.8 0.1 7.5 4 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM08316.1 - 3.8e-38 125.7 15.8 1.6e-07 30.8 0.0 9.8 9 1 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.1 KFM08316.1 - 3.2e-37 125.7 16.0 4.2e-08 33.1 0.2 9.0 4 2 4 8 8 8 7 Ankyrin repeats (many copies) CLN6 PF15156.1 KFM08317.1 - 3.6e-151 502.0 18.9 4e-151 501.9 13.1 1.0 1 0 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 6 Zn_dep_PLPC PF00882.13 KFM08317.1 - 0.0087 15.7 0.1 0.014 15.0 0.1 1.4 1 0 0 1 1 1 1 Zinc dependent phospholipase C DUF3397 PF11877.3 KFM08317.1 - 0.04 13.9 0.1 0.04 13.9 0.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3397) DUF3959 PF13105.1 KFM08317.1 - 0.25 10.6 3.8 0.39 9.9 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Herpes_LMP1 PF05297.6 KFM08317.1 - 0.34 9.7 7.0 0.11 11.4 2.9 1.5 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) EF-hand_7 PF13499.1 KFM08318.1 - 4e-14 52.4 0.0 8.8e-06 25.7 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KFM08318.1 - 5.9e-11 40.8 1.5 0.0007 18.7 0.0 4.5 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 KFM08318.1 - 2.6e-10 39.7 0.3 3.3e-06 26.6 0.0 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 KFM08318.1 - 3.6e-10 38.8 0.3 0.00014 21.4 0.0 4.3 3 1 1 4 4 4 2 EF-hand domain EF-hand_9 PF14658.1 KFM08318.1 - 6e-10 38.8 0.0 0.00013 21.8 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain UPF0154 PF03672.8 KFM08318.1 - 0.0098 15.4 0.2 0.3 10.7 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) EF-hand_4 PF12763.2 KFM08318.1 - 0.024 14.3 0.0 5.8 6.7 0.0 2.2 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand PINIT PF14324.1 KFM08319.1 - 6.9e-46 155.9 0.2 1.8e-45 154.5 0.1 1.8 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 KFM08319.1 - 4.2e-20 70.9 5.2 8.6e-20 69.9 3.6 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 KFM08319.1 - 0.00087 18.7 1.7 0.0024 17.3 1.2 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.22 KFM08319.1 - 0.0097 15.4 0.2 0.024 14.1 0.1 1.7 1 0 0 1 1 1 1 SAP domain zf-C3HC4 PF00097.20 KFM08319.1 - 0.57 9.8 4.9 2.2 8.0 3.4 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 KFM08319.1 - 5.4 6.7 8.5 0.29 10.8 1.7 2.1 2 0 0 2 2 2 0 PHD-finger Pkinase PF00069.20 KFM08321.1 - 2.5e-59 200.5 0.0 3.2e-59 200.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM08321.1 - 2.1e-38 131.8 0.0 2.8e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PB1 PF00564.19 KFM08321.1 - 1.4e-07 31.0 0.1 3.2e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 PB1 domain Kinase-like PF14531.1 KFM08321.1 - 2.9e-06 26.4 0.0 9.4e-06 24.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 KFM08321.1 - 0.079 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 KFM08321.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Adaptin_binding PF10199.4 KFM08322.1 - 1.6e-24 86.7 2.8 2.1e-24 86.3 2.0 1.2 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Ras PF00071.17 KFM08322.1 - 0.016 14.6 0.0 0.03 13.6 0.0 1.4 1 0 0 1 1 1 0 Ras family MH2 PF03166.9 KFM08323.1 - 4.6e-77 257.9 0.0 6.3e-77 257.5 0.0 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.11 KFM08323.1 - 7.7e-44 147.9 3.1 7.7e-44 147.9 2.1 2.0 2 0 0 2 2 2 1 MH1 domain IRF-3 PF10401.4 KFM08323.1 - 7.9e-05 22.3 0.0 0.00014 21.4 0.0 1.4 1 0 0 1 1 1 1 Interferon-regulatory factor 3 MH2 PF03166.9 KFM08324.1 - 8.2e-58 195.2 0.0 9.1e-58 195.0 0.0 1.0 1 0 0 1 1 1 1 MH2 domain IRF-3 PF10401.4 KFM08324.1 - 0.036 13.6 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 Interferon-regulatory factor 3 Glyco_hydro_1 PF00232.13 KFM08326.1 - 4.9e-163 542.5 6.9 5.6e-163 542.3 4.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 DUF3377 PF11857.3 KFM08326.1 - 0.24 11.0 1.9 0.31 10.6 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) DUF2352 PF09817.4 KFM08327.1 - 4.6e-165 550.1 4.0 8.7e-165 549.2 2.7 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2352) Ribosomal_L4 PF00573.17 KFM08328.1 - 2.9e-45 154.0 0.1 5.3e-45 153.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 KFM08328.1 - 1.3e-31 108.2 8.2 3.6e-31 106.8 5.7 1.8 1 0 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain Pkinase PF00069.20 KFM08329.1 - 1.1e-61 208.3 0.0 1.3e-61 208.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM08329.1 - 1.2e-34 119.5 0.0 5.8e-33 114.0 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KFM08329.1 - 0.0051 15.8 0.0 0.013 14.4 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KFM08329.1 - 0.012 14.4 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF4089 PF13318.1 KFM08329.1 - 0.11 12.7 0.8 0.58 10.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4089) Swi3 PF07962.7 KFM08330.1 - 2.6e-36 123.0 0.3 4.7e-36 122.2 0.2 1.4 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 RNB PF00773.14 KFM08331.1 - 8.4e-85 284.9 0.1 1.7e-84 283.8 0.1 1.5 1 0 0 1 1 1 1 RNB domain OB_RNB PF08206.6 KFM08331.1 - 0.14 11.6 0.0 0.58 9.7 0.0 2.0 1 0 0 1 1 1 0 Ribonuclease B OB domain EMI PF07546.8 KFM08332.1 - 1.3e-14 54.4 7.3 1.3e-14 54.4 5.1 2.0 2 0 0 2 2 2 1 EMI domain EGF_2 PF07974.8 KFM08332.1 - 0.32 11.1 18.5 0.41 10.8 11.5 2.2 1 1 1 2 2 2 0 EGF-like domain Laminin_EGF PF00053.19 KFM08333.1 - 1.8e-53 178.2 292.2 0.00036 20.4 11.1 16.9 6 5 10 16 16 16 16 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 KFM08333.1 - 7.9e-08 32.3 371.4 0.0016 18.5 9.1 25.3 21 9 3 24 24 24 12 EGF-like domain hEGF PF12661.2 KFM08333.1 - 0.00058 19.7 20.9 0.0041 17.1 1.7 31.5 35 0 0 35 35 35 15 Human growth factor-like EGF Rifin_STEVOR PF02009.11 KFM08333.1 - 0.0044 16.6 0.0 0.0073 15.9 0.0 1.2 1 0 0 1 1 1 1 Rifin/stevor family SIT PF15330.1 KFM08333.1 - 0.021 14.9 0.2 0.059 13.5 0.0 1.7 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT BatD PF13584.1 KFM08333.1 - 0.2 10.2 0.0 0.27 9.8 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance Syndecan PF01034.15 KFM08333.1 - 0.25 11.0 0.0 0.5 10.0 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.5 KFM08333.1 - 0.32 10.3 4.4 0.55 9.5 3.1 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2207 PF09972.4 KFM08333.1 - 0.34 9.4 0.1 0.46 9.0 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CoatB PF10389.4 KFM08333.1 - 0.86 9.5 2.2 1.5 8.7 1.5 1.3 1 0 0 1 1 1 0 Bacteriophage coat protein B Ras PF00071.17 KFM08334.1 - 1.1e-62 210.2 0.1 1.2e-62 210.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM08334.1 - 1.1e-20 74.2 0.0 1.7e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM08334.1 - 2.1e-11 43.4 0.1 2.5e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFM08334.1 - 1.5e-07 31.3 0.0 2.5e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KFM08334.1 - 8.1e-07 29.2 0.1 2.6e-06 27.5 0.0 1.8 2 1 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 KFM08334.1 - 1.8e-05 24.2 0.0 3.6e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KFM08334.1 - 0.0025 17.0 0.1 0.0056 15.8 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_15 PF13175.1 KFM08334.1 - 0.0042 16.1 0.0 0.0047 16.0 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 KFM08334.1 - 0.0053 16.6 0.0 0.011 15.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 KFM08334.1 - 0.0055 15.8 0.0 0.0098 15.0 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 KFM08334.1 - 0.013 15.4 0.3 0.041 13.8 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.13 KFM08334.1 - 0.021 14.1 0.1 0.1 11.8 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.22 KFM08334.1 - 0.028 14.7 0.1 0.038 14.2 0.1 1.6 1 1 0 1 1 1 0 ABC transporter SRPRB PF09439.5 KFM08334.1 - 0.064 12.4 0.0 0.1 11.7 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 KFM08334.1 - 0.11 12.0 0.0 0.28 10.6 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DENN PF02141.16 KFM08335.1 - 4.9e-59 199.1 4.0 4.9e-59 199.1 2.8 2.1 2 0 0 2 2 2 1 DENN (AEX-3) domain dDENN PF03455.14 KFM08335.1 - 4.1e-22 78.0 0.6 4.1e-22 78.0 0.4 1.9 2 0 0 2 2 2 1 dDENN domain uDENN PF03456.13 KFM08335.1 - 5.1e-08 32.7 0.7 2e-07 30.8 0.3 2.2 2 0 0 2 2 2 1 uDENN domain PPR_2 PF13041.1 KFM08335.1 - 2.9e-07 30.3 0.0 1.4e-05 24.9 0.0 2.5 1 1 1 2 2 2 2 PPR repeat family PPR PF01535.15 KFM08335.1 - 0.0086 15.9 0.0 0.044 13.7 0.0 2.3 2 0 0 2 2 2 1 PPR repeat PPR_3 PF13812.1 KFM08335.1 - 0.014 15.6 0.0 0.052 13.8 0.0 2.1 2 0 0 2 2 2 0 Pentatricopeptide repeat domain Na_Ca_ex PF01699.19 KFM08336.1 - 5.2e-58 194.6 41.5 1.8e-31 108.5 7.8 2.5 3 0 0 3 3 3 2 Sodium/calcium exchanger protein PBP1_TM PF14812.1 KFM08336.1 - 0.013 15.7 2.7 0.013 15.7 1.9 2.6 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ESSS PF10183.4 KFM08336.1 - 0.23 11.8 0.7 2.5 8.5 0.0 3.2 3 1 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) CENP-B_dimeris PF09026.5 KFM08336.1 - 0.43 10.8 6.3 0.99 9.6 4.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PPP4R2 PF09184.6 KFM08336.1 - 1.4 8.3 11.9 2.1 7.7 8.2 1.3 1 0 0 1 1 1 0 PPP4R2 Cwf_Cwc_15 PF04889.7 KFM08336.1 - 2.1 7.9 21.1 3.4 7.3 14.7 1.4 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TFIIA PF03153.8 KFM08336.1 - 2.2 8.0 17.4 3.8 7.3 12.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3449 PF11931.3 KFM08336.1 - 7.9 5.9 7.3 2.1 7.8 2.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) VWA_2 PF13519.1 KFM08337.1 - 1.3e-08 35.1 0.0 2.2e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain PTPLA PF04387.9 KFM08338.1 - 1.7e-60 203.1 4.2 1.7e-60 203.1 2.9 1.5 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA ELO PF01151.13 KFM08338.1 - 0.01 15.1 13.6 0.02 14.2 9.5 1.4 1 1 0 1 1 1 0 GNS1/SUR4 family DPPIV_N PF00930.16 KFM08339.1 - 1.7e-97 326.1 0.0 2.3e-97 325.7 0.0 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 KFM08339.1 - 1.1e-59 201.2 0.0 1.8e-59 200.5 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 KFM08339.1 - 1.8e-08 34.1 0.0 3.3e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.2 KFM08339.1 - 4.8e-08 32.8 0.0 1.6e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFM08339.1 - 0.00019 21.3 0.0 0.00041 20.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KFM08339.1 - 0.026 13.9 0.0 0.8 9.1 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase PF00756.15 KFM08339.1 - 0.06 12.7 0.1 0.25 10.7 0.1 2.0 1 1 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.8 KFM08339.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.13 KFM08339.1 - 0.13 11.5 0.1 0.88 8.8 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family fn3 PF00041.16 KFM08340.1 - 1.4e-64 214.1 13.8 7.6e-16 58.0 1.1 5.5 5 0 0 5 5 5 5 Fibronectin type III domain I-set PF07679.11 KFM08340.1 - 6.3e-51 170.1 0.1 4.2e-18 64.9 0.0 5.6 5 1 0 5 5 5 4 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM08340.1 - 3.3e-34 116.8 0.0 1.4e-08 34.7 0.0 4.6 4 0 0 4 4 4 4 Immunoglobulin domain Ig_3 PF13927.1 KFM08340.1 - 1.1e-25 89.8 3.6 7.7e-08 32.7 0.0 6.5 6 0 0 6 6 6 3 Immunoglobulin domain ig PF00047.20 KFM08340.1 - 1.5e-25 89.0 0.0 1.6e-07 31.2 0.0 5.8 6 0 0 6 6 6 3 Immunoglobulin domain V-set PF07686.12 KFM08340.1 - 9.1e-18 64.2 0.1 0.00073 19.4 0.0 6.5 5 2 0 5 5 5 3 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM08340.1 - 1e-09 38.1 0.4 0.093 12.6 0.0 4.5 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Interfer-bind PF09294.5 KFM08340.1 - 7.4e-05 22.7 1.6 0.11 12.5 0.2 4.0 4 0 0 4 4 4 1 Interferon-alpha/beta receptor, fibronectin type III SusE PF14292.1 KFM08340.1 - 0.01 15.6 0.7 0.69 9.7 0.0 3.4 3 0 0 3 3 3 0 SusE outer membrane protein C1-set PF07654.10 KFM08340.1 - 0.034 14.1 0.1 0.81 9.7 0.0 3.3 3 0 0 3 3 3 0 Immunoglobulin C1-set domain Adeno_E3_CR2 PF02439.10 KFM08340.1 - 0.28 10.7 5.4 0.73 9.4 3.8 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 I-set PF07679.11 KFM08341.1 - 8.8e-60 198.5 0.0 1.2e-21 76.3 0.0 4.9 5 0 0 5 5 5 4 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM08341.1 - 1.2e-37 127.8 0.0 4.2e-08 33.2 0.0 4.6 4 0 0 4 4 4 4 Immunoglobulin domain Ig_3 PF13927.1 KFM08341.1 - 1.5e-26 92.6 0.2 1.2e-06 28.9 0.1 5.7 5 1 0 5 5 5 4 Immunoglobulin domain fn3 PF00041.16 KFM08341.1 - 7.4e-23 80.4 2.9 1.4e-13 50.7 0.4 2.8 2 0 0 2 2 2 2 Fibronectin type III domain ig PF00047.20 KFM08341.1 - 8e-21 73.9 0.1 3.4e-06 27.1 0.0 5.1 4 1 0 4 4 4 3 Immunoglobulin domain V-set PF07686.12 KFM08341.1 - 1.6e-19 69.8 2.2 9.7e-06 25.4 0.0 5.9 5 3 0 5 5 5 3 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM08341.1 - 2.4e-14 53.0 0.3 1.8e-06 27.7 0.1 4.7 4 0 0 4 4 4 3 CD80-like C2-set immunoglobulin domain C1-set PF07654.10 KFM08341.1 - 3.4e-07 30.1 0.6 0.013 15.4 0.0 4.0 5 1 0 5 5 4 2 Immunoglobulin C1-set domain C2-set PF05790.10 KFM08341.1 - 0.0022 17.8 0.0 34 4.5 0.0 4.2 4 0 0 4 4 4 0 Immunoglobulin C2-set domain Interfer-bind PF09294.5 KFM08341.1 - 0.0086 16.1 0.4 0.024 14.6 0.3 1.7 1 0 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III Adeno_E3_CR2 PF02439.10 KFM08341.1 - 0.27 10.8 4.1 0.64 9.6 2.9 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 PARP PF00644.15 KFM08342.1 - 4.5e-35 120.9 0.1 5.9e-35 120.5 0.1 1.1 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain 7tm_1 PF00001.16 KFM08343.1 - 2.3e-52 177.6 13.0 3e-52 177.3 9.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM08343.1 - 1e-07 31.4 6.9 1.3e-07 31.0 4.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Git3 PF11710.3 KFM08343.1 - 0.07 12.6 7.0 0.12 11.8 4.9 1.5 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 DUF4480 PF13715.1 KFM08344.1 - 6e-13 48.6 0.0 3.4e-07 30.2 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4480) CarboxypepD_reg PF13620.1 KFM08344.1 - 4.4e-11 42.6 0.2 4.7e-08 32.9 0.0 3.0 3 0 0 3 3 3 2 Carboxypeptidase regulatory-like domain Ig_2 PF13895.1 KFM08344.1 - 5.5e-11 42.4 0.0 1.7e-10 40.8 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 KFM08344.1 - 2.4e-08 33.6 0.0 6.7e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.1 KFM08344.1 - 2.4e-06 27.9 0.2 1.2e-05 25.6 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain TSP_1 PF00090.14 KFM08344.1 - 5.8e-06 26.3 11.3 5.8e-06 26.3 7.8 3.0 3 0 0 3 3 3 1 Thrombospondin type 1 domain ig PF00047.20 KFM08344.1 - 0.00014 21.8 0.0 0.00051 20.0 0.0 2.1 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFM08344.1 - 0.011 15.5 2.0 0.041 13.7 0.0 2.9 3 1 1 4 4 4 0 Immunoglobulin V-set domain Perm-CXXC PF15629.1 KFM08344.1 - 2.5 8.1 9.7 0.039 13.9 1.2 2.2 2 0 0 2 2 2 0 Permuted single zf-CXXC unit Formyl_trans_N PF00551.14 KFM08345.1 - 4.6e-28 97.9 0.0 7.7e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 KFM08345.1 - 1e-09 38.3 0.0 2.3e-09 37.2 0.0 1.6 2 0 0 2 2 2 1 Formyl transferase, C-terminal domain DUF4034 PF13226.1 KFM08345.1 - 0.057 12.5 0.5 0.29 10.1 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4034) OSTbeta PF15048.1 KFM08346.1 - 6.8e-34 116.6 0.1 8e-34 116.4 0.1 1.0 1 0 0 1 1 1 1 Organic solute transporter subunit beta protein GP41 PF00517.12 KFM08346.1 - 0.029 13.9 0.0 0.038 13.5 0.0 1.1 1 0 0 1 1 1 0 Retroviral envelope protein DUF4381 PF14316.1 KFM08346.1 - 0.031 14.3 0.1 0.042 13.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) IncA PF04156.9 KFM08346.1 - 0.074 12.6 0.2 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 IncA protein DUF2474 PF10617.4 KFM08346.1 - 0.089 12.4 2.0 0.17 11.4 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2474) Ras PF00071.17 KFM08347.1 - 7.7e-32 109.9 0.0 1e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM08347.1 - 1.2e-12 48.3 0.0 2.8e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM08347.1 - 0.0027 16.9 0.0 0.0042 16.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF815 PF05673.8 KFM08347.1 - 0.056 12.3 0.0 1.5 7.7 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF815) Kelch_1 PF01344.20 KFM08348.1 - 9.1e-21 73.1 6.1 1.3e-07 31.0 0.0 5.5 4 1 0 4 4 4 3 Kelch motif Kelch_6 PF13964.1 KFM08348.1 - 2.4e-15 55.9 6.2 0.00017 21.6 0.0 5.3 5 2 1 6 6 6 3 Kelch motif Kelch_4 PF13418.1 KFM08348.1 - 1.5e-11 43.8 4.1 0.00065 19.4 0.0 5.3 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.10 KFM08348.1 - 3.9e-10 39.0 1.8 0.00051 19.6 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.1 KFM08348.1 - 1.2e-07 31.7 0.1 0.32 11.2 0.0 4.6 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.1 KFM08348.1 - 0.00084 19.2 4.7 2.2 8.3 0.1 4.0 3 1 0 3 3 3 2 Kelch motif DUF1668 PF07893.8 KFM08348.1 - 0.0022 17.1 0.5 0.18 10.8 0.0 2.3 1 1 2 3 3 3 1 Protein of unknown function (DUF1668) UBA PF00627.26 KFM08349.1 - 2e-05 24.2 2.0 0.13 12.1 0.1 2.2 2 0 0 2 2 2 2 UBA/TS-N domain Sigma54_CBD PF04963.8 KFM08349.1 - 0.00035 20.0 0.3 0.00041 19.8 0.2 1.1 1 0 0 1 1 1 1 Sigma-54 factor, core binding domain UBA_3 PF09288.5 KFM08349.1 - 0.029 13.9 1.1 0.74 9.4 0.5 2.5 2 1 0 2 2 2 0 Fungal ubiquitin-associated domain UBA_2 PF08587.6 KFM08349.1 - 0.076 13.2 0.0 4.6 7.5 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) Chordopox_G3 PF06129.7 KFM08351.1 - 1.2 9.3 3.2 2.2 8.4 0.9 2.1 2 0 0 2 2 2 0 Chordopoxvirus G3 protein AAA_2 PF07724.9 KFM08352.1 - 7.2e-42 143.1 0.0 1.2e-41 142.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 KFM08352.1 - 1.1e-15 57.2 0.0 2.7e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 KFM08352.1 - 7.2e-14 52.1 0.0 1.3e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFM08352.1 - 9.4e-06 25.3 0.0 2.5e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 KFM08352.1 - 1.2e-05 24.8 0.0 9.1e-05 21.9 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.1 KFM08352.1 - 4.2e-05 23.6 0.0 7.4e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFM08352.1 - 6.3e-05 23.1 0.1 0.00034 20.7 0.1 2.2 1 1 1 2 2 1 1 AAA domain Mg_chelatase PF01078.16 KFM08352.1 - 8.5e-05 21.8 0.0 0.0085 15.2 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 KFM08352.1 - 0.00051 20.8 0.0 0.0013 19.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KFM08352.1 - 0.00063 19.6 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KFM08352.1 - 0.0011 18.4 0.0 0.0032 16.9 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein T2SE PF00437.15 KFM08352.1 - 0.003 16.4 0.0 0.0052 15.7 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Sigma54_activ_2 PF14532.1 KFM08352.1 - 0.0032 17.4 0.0 0.0099 15.9 0.0 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain RuvB_N PF05496.7 KFM08352.1 - 0.0079 15.2 0.0 0.015 14.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 KFM08352.1 - 0.011 15.3 0.3 0.049 13.2 0.2 2.1 1 1 0 1 1 1 0 NACHT domain AAA_25 PF13481.1 KFM08352.1 - 0.015 14.6 0.0 0.031 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KFM08352.1 - 0.016 15.5 0.0 0.052 13.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KFM08352.1 - 0.017 14.8 0.0 0.048 13.4 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain DEAD PF00270.24 KFM08352.1 - 0.047 13.1 0.2 0.27 10.7 0.0 2.1 1 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_33 PF13671.1 KFM08352.1 - 0.047 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KFM08352.1 - 0.049 13.9 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter UPF0079 PF02367.12 KFM08352.1 - 0.06 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ResIII PF04851.10 KFM08352.1 - 0.061 13.1 0.0 0.22 11.3 0.0 1.9 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit TIP49 PF06068.8 KFM08352.1 - 0.068 11.8 0.0 0.11 11.1 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus PhoH PF02562.11 KFM08352.1 - 0.074 12.2 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_29 PF13555.1 KFM08352.1 - 0.1 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.4 KFM08352.1 - 0.13 11.7 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 KFM08352.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KFM08352.1 - 0.14 12.3 0.0 0.63 10.2 0.0 2.2 2 0 0 2 2 1 0 RNA helicase TrwB_AAD_bind PF10412.4 KFM08352.1 - 0.18 10.3 0.0 1.4 7.5 0.0 1.9 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain zinc_ribbon_4 PF13717.1 KFM08352.1 - 0.39 10.4 5.2 6.5 6.5 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 KFM08352.1 - 1.5 8.7 4.6 2.9 7.7 3.2 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zinc_ribbon_5 PF13719.1 KFM08352.1 - 1.8 8.2 8.9 7.1 6.3 0.8 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Abhydrolase_6 PF12697.2 KFM08353.1 - 5.1e-13 49.4 0.0 7e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFM08353.1 - 8.6e-08 32.0 0.0 3.3e-07 30.0 0.0 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFM08353.1 - 3.3e-07 30.1 0.0 4.4e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KFM08353.1 - 0.0028 17.9 0.0 0.0067 16.6 0.0 1.6 2 0 0 2 2 2 1 Thioesterase domain Ndr PF03096.9 KFM08353.1 - 0.0057 15.1 0.0 0.0084 14.6 0.0 1.2 1 0 0 1 1 1 1 Ndr family Ank_2 PF12796.2 KFM08354.1 - 6.7e-56 186.6 16.6 5e-19 68.4 2.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFM08354.1 - 4.9e-53 176.6 25.2 2.9e-11 43.5 0.2 5.9 3 1 4 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.25 KFM08354.1 - 6.7e-53 173.9 19.5 2.5e-11 42.7 0.1 9.2 9 0 0 9 9 9 9 Ankyrin repeat Ank_5 PF13857.1 KFM08354.1 - 1.7e-42 142.4 18.2 6e-10 39.0 0.0 8.4 1 1 8 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM08354.1 - 2.2e-36 120.2 18.6 1.9e-05 24.4 0.1 9.2 9 0 0 9 9 9 8 Ankyrin repeat Death PF00531.17 KFM08354.1 - 1.2e-12 47.3 0.1 2.7e-12 46.3 0.1 1.6 1 0 0 1 1 1 1 Death domain SCO1-SenC PF02630.9 KFM08354.1 - 0.12 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 SCO1/SenC Peptidase_S8 PF00082.17 KFM08355.1 - 2.6e-56 190.8 0.3 3.4e-56 190.4 0.2 1.1 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 KFM08355.1 - 8e-34 115.2 0.1 1.4e-33 114.5 0.1 1.4 1 0 0 1 1 1 1 Proprotein convertase P-domain GF_recep_IV PF14843.1 KFM08355.1 - 1.2e-07 31.3 3.9 4e-07 29.7 2.7 1.9 1 0 0 1 1 1 1 Growth factor receptor domain IV Furin-like PF00757.15 KFM08355.1 - 0.021 14.4 4.8 0.052 13.1 3.3 1.7 1 0 0 1 1 1 0 Furin-like cysteine rich region Syndecan PF01034.15 KFM08356.1 - 3.4e-32 109.9 0.1 5.2e-32 109.2 0.1 1.3 1 0 0 1 1 1 1 Syndecan domain Glycophorin_A PF01102.13 KFM08356.1 - 0.067 12.9 2.2 0.14 11.9 0.0 2.5 2 1 0 2 2 2 0 Glycophorin A PUF PF00806.14 KFM08357.1 - 2.5e-74 240.7 8.7 8.7e-10 37.5 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Mt_ATP-synt_B PF05405.9 KFM08357.1 - 3.5 7.0 6.1 9.7 5.6 0.1 3.1 3 1 0 3 3 3 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) AA_permease_2 PF13520.1 KFM08358.1 - 2.7e-58 197.4 45.2 3.6e-58 197.0 31.3 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFM08358.1 - 1.1e-25 90.0 42.3 1.9e-25 89.1 29.3 1.4 1 1 0 1 1 1 1 Amino acid permease Ras PF00071.17 KFM08359.1 - 1.3e-36 125.4 0.0 1.4e-36 125.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM08359.1 - 2.5e-14 53.8 0.0 3.2e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM08359.1 - 8e-09 34.9 0.0 1.2e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.4 KFM08359.1 - 0.00065 19.1 0.1 0.015 14.7 0.1 2.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 KFM08359.1 - 0.0025 17.0 0.0 0.0038 16.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KFM08359.1 - 0.0047 16.8 0.0 0.007 16.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 KFM08360.1 - 1.2e-57 193.8 0.0 1.4e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM08360.1 - 2.6e-17 63.4 0.0 3.9e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM08360.1 - 5.4e-11 42.0 0.0 1e-10 41.1 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFM08360.1 - 7e-05 22.3 0.1 0.00018 21.0 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFM08360.1 - 0.0061 15.7 0.0 0.0083 15.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KFM08360.1 - 0.042 13.0 0.0 0.065 12.4 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit BAF PF02961.9 KFM08361.1 - 3.2e-22 78.6 0.8 3.5e-22 78.5 0.5 1.0 1 0 0 1 1 1 1 Barrier to autointegration factor PX PF00787.19 KFM08362.1 - 3.9e-13 49.1 0.8 8.4e-13 48.1 0.0 1.9 2 0 0 2 2 2 1 PX domain HTH_24 PF13412.1 KFM08362.1 - 0.13 11.6 0.4 0.36 10.2 0.3 1.7 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding TGF_beta PF00019.15 KFM08363.1 - 5.8e-38 129.3 0.3 8.2e-38 128.8 0.2 1.2 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.13 KFM08363.1 - 1.7e-16 60.2 0.0 2.6e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 TGF-beta propeptide DUF2305 PF10230.4 KFM08364.1 - 3.1e-85 285.8 0.0 3.7e-85 285.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 KFM08364.1 - 1.5e-09 38.1 0.0 2.4e-09 37.4 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFM08364.1 - 0.00013 21.7 0.0 0.00024 20.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 KFM08364.1 - 0.0016 18.0 0.0 0.0077 15.8 0.0 1.9 2 0 0 2 2 2 1 Serine hydrolase DUF900 PF05990.7 KFM08364.1 - 0.056 12.7 0.1 0.13 11.6 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.10 KFM08364.1 - 0.12 11.3 0.1 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Vitellogenin_N PF01347.17 KFM08365.1 - 4.3e-63 213.5 0.2 4.3e-63 213.5 0.2 2.6 2 0 0 2 2 2 1 Lipoprotein amino terminal region DUF1943 PF09172.6 KFM08365.1 - 1.3e-62 211.3 4.7 1.4e-62 211.2 0.1 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1943) DUF1081 PF06448.6 KFM08365.1 - 4.3e-31 107.2 0.0 3.5e-30 104.3 0.0 2.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1081) ApoB100_C PF12491.3 KFM08365.1 - 3.6e-25 87.3 1.2 3.6e-25 87.3 0.9 3.3 2 0 0 2 2 2 1 Apolipoprotein B100 C terminal Apolipoprotein PF01442.13 KFM08365.1 - 0.0018 17.7 1.3 0.0018 17.7 0.9 6.7 5 2 1 7 7 7 3 Apolipoprotein A1/A4/E domain 7tm_4 PF13853.1 KFM08366.1 - 3e-59 198.9 6.2 3e-59 198.9 4.3 2.2 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFM08366.1 - 7.9e-35 120.2 9.2 1.2e-34 119.6 6.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 KFM08366.1 - 0.00024 20.3 9.6 0.00047 19.3 5.5 2.0 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.4 KFM08366.1 - 0.0009 18.4 7.1 0.0017 17.5 4.9 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Glycolytic PF00274.14 KFM08367.1 - 5.1e-116 386.8 0.0 1.2e-115 385.5 0.0 1.5 1 1 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Metallophos PF00149.23 KFM08368.1 - 2.6e-25 89.0 0.0 3.3e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Nup160 PF11715.3 KFM08369.1 - 1.1e-100 337.3 0.0 1.4e-100 337.0 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 RhoGEF PF00621.15 KFM08370.1 - 1.1e-16 61.2 0.0 1.2e-16 61.0 0.0 1.0 1 0 0 1 1 1 1 RhoGEF domain DUF793 PF05633.6 KFM08370.1 - 0.1 11.3 0.0 0.11 11.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF793) A2M_comp PF07678.9 KFM08371.1 - 4.5e-80 268.4 0.9 7e-80 267.7 0.6 1.3 1 0 0 1 1 1 1 A-macroglobulin complement component A2M_N_2 PF07703.9 KFM08371.1 - 4.6e-37 126.8 0.2 3.5e-35 120.7 0.0 2.8 2 1 1 3 3 3 1 Alpha-2-macroglobulin family N-terminal region A2M PF00207.17 KFM08371.1 - 1.8e-28 97.9 0.1 4.6e-28 96.6 0.1 1.8 1 0 0 1 1 1 1 Alpha-2-macroglobulin family A2M_recep PF07677.9 KFM08371.1 - 1.2e-25 89.4 2.3 3.2e-25 88.1 1.6 1.8 1 0 0 1 1 1 1 A-macroglobulin receptor A2M_N PF01835.14 KFM08371.1 - 3.5e-22 78.5 0.1 3.7e-21 75.2 0.0 2.9 3 0 0 3 3 3 1 MG2 domain Thiol-ester_cl PF10569.4 KFM08371.1 - 2.1e-17 62.0 1.0 4.8e-17 60.8 0.7 1.7 1 0 0 1 1 1 1 Alpha-macro-globulin thiol-ester bond-forming region Prenyltrans_2 PF13249.1 KFM08371.1 - 1.4e-16 60.8 3.5 1.5e-08 34.9 0.0 3.6 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 KFM08371.1 - 9.6e-06 25.5 0.0 0.18 11.8 0.0 2.5 2 0 0 2 2 2 2 Prenyltransferase-like SVA PF05326.6 KFM08371.1 - 0.01 15.6 0.0 0.029 14.1 0.0 1.7 1 0 0 1 1 1 0 Seminal vesicle autoantigen (SVA) Prenyltrans PF00432.16 KFM08371.1 - 0.015 14.8 0.2 0.058 12.9 0.0 2.2 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat DNA_pol_B_palm PF14792.1 KFM08371.1 - 0.025 14.6 0.0 0.054 13.5 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase beta palm Big_1 PF02369.11 KFM08371.1 - 0.28 11.1 2.8 0.3 11.0 0.0 2.4 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 1) A2M_comp PF07678.9 KFM08372.1 - 7.2e-86 287.4 1.2 1.1e-85 286.8 0.8 1.3 1 0 0 1 1 1 1 A-macroglobulin complement component A2M_N_2 PF07703.9 KFM08372.1 - 3.2e-34 117.6 1.0 4e-32 110.8 0.1 3.5 3 1 0 3 3 3 1 Alpha-2-macroglobulin family N-terminal region A2M PF00207.17 KFM08372.1 - 2.5e-28 97.4 0.5 2e-27 94.5 0.0 2.8 3 0 0 3 3 3 1 Alpha-2-macroglobulin family A2M_recep PF07677.9 KFM08372.1 - 1e-27 96.0 2.1 3.2e-27 94.5 1.5 1.9 1 0 0 1 1 1 1 A-macroglobulin receptor A2M_N PF01835.14 KFM08372.1 - 2.8e-22 78.8 0.0 1.6e-21 76.4 0.0 2.4 1 0 0 1 1 1 1 MG2 domain Thiol-ester_cl PF10569.4 KFM08372.1 - 2e-16 58.8 0.5 8.9e-16 56.8 0.4 2.1 2 0 0 2 2 2 1 Alpha-macro-globulin thiol-ester bond-forming region Prenyltrans_2 PF13249.1 KFM08372.1 - 2.9e-11 43.7 2.2 0.00011 22.5 0.0 3.1 1 1 2 3 3 3 3 Prenyltransferase-like SVA PF05326.6 KFM08372.1 - 4.2e-05 23.3 0.1 0.00041 20.1 0.0 2.6 2 0 0 2 2 2 1 Seminal vesicle autoantigen (SVA) Prenyltrans_1 PF13243.1 KFM08372.1 - 0.00069 19.6 0.1 0.42 10.6 0.0 2.7 2 0 0 2 2 2 2 Prenyltransferase-like Apc3 PF12895.2 KFM08372.1 - 0.074 13.1 0.3 0.17 12.0 0.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Prenyltrans PF00432.16 KFM08372.1 - 0.094 12.3 1.3 0.54 9.8 0.2 2.8 2 1 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat A2M_comp PF07678.9 KFM08373.1 - 2.9e-88 295.2 0.1 4.6e-88 294.5 0.0 1.3 1 0 0 1 1 1 1 A-macroglobulin complement component A2M_N_2 PF07703.9 KFM08373.1 - 1.3e-32 112.4 1.3 7.4e-31 106.7 0.1 3.6 4 0 0 4 4 4 1 Alpha-2-macroglobulin family N-terminal region A2M PF00207.17 KFM08373.1 - 7.2e-30 102.4 0.2 2.5e-29 100.6 0.2 2.0 1 0 0 1 1 1 1 Alpha-2-macroglobulin family A2M_recep PF07677.9 KFM08373.1 - 3.3e-28 97.6 0.3 1.3e-27 95.7 0.2 2.2 1 0 0 1 1 1 1 A-macroglobulin receptor Thiol-ester_cl PF10569.4 KFM08373.1 - 2.1e-16 58.8 0.9 5.1e-16 57.5 0.6 1.7 1 0 0 1 1 1 1 Alpha-macro-globulin thiol-ester bond-forming region A2M_N PF01835.14 KFM08373.1 - 3.5e-16 59.2 0.0 1.3e-15 57.4 0.0 2.1 1 0 0 1 1 1 1 MG2 domain Prenyltrans_2 PF13249.1 KFM08373.1 - 2.1e-12 47.4 0.7 0.00045 20.5 0.0 3.5 1 1 2 3 3 3 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 KFM08373.1 - 0.0002 21.3 0.1 0.34 10.9 0.0 2.8 2 0 0 2 2 2 2 Prenyltransferase-like SVA PF05326.6 KFM08373.1 - 0.00071 19.3 0.2 0.0026 17.5 0.0 2.0 2 0 0 2 2 2 1 Seminal vesicle autoantigen (SVA) CarboxypepD_reg PF13620.1 KFM08373.1 - 0.0038 17.2 0.2 0.13 12.3 0.0 3.2 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain Man-6-P_recep PF02157.10 KFM08374.1 - 2.3e-128 427.0 0.2 2.5e-128 426.9 0.2 1.0 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.5 KFM08374.1 - 0.00012 21.3 0.4 0.00051 19.3 0.3 1.9 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 KFM08374.1 - 0.0013 18.5 0.1 0.094 12.4 0.0 2.3 2 0 0 2 2 2 1 Cation-independent mannose-6-phosphate receptor repeat PRKCSH_1 PF13015.1 KFM08374.1 - 0.032 13.6 0.1 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein SAM_1 PF00536.25 KFM08375.1 - 1.3e-16 60.5 0.0 2.6e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFM08375.1 - 1.8e-10 40.5 0.0 3.6e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-FCS PF06467.9 KFM08375.1 - 4.2e-06 26.2 2.4 8.4e-06 25.3 1.7 1.6 1 0 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif SAM_PNT PF02198.11 KFM08375.1 - 0.004 16.8 0.0 0.0091 15.7 0.0 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain A2M_comp PF07678.9 KFM08376.1 - 4.9e-78 261.7 0.1 7e-78 261.2 0.0 1.2 1 0 0 1 1 1 1 A-macroglobulin complement component A2M PF00207.17 KFM08376.1 - 1.8e-23 81.8 0.1 8e-23 79.8 0.1 2.2 2 0 0 2 2 2 1 Alpha-2-macroglobulin family A2M_recep PF07677.9 KFM08376.1 - 5.6e-20 71.3 0.0 1.1e-19 70.3 0.0 1.6 1 0 0 1 1 1 1 A-macroglobulin receptor A2M_N_2 PF07703.9 KFM08376.1 - 4.6e-19 68.5 0.0 1.6e-18 66.7 0.0 2.0 2 0 0 2 2 2 1 Alpha-2-macroglobulin family N-terminal region Thiol-ester_cl PF10569.4 KFM08376.1 - 5.4e-17 60.7 1.4 1.2e-16 59.6 0.2 2.3 2 0 0 2 2 2 1 Alpha-macro-globulin thiol-ester bond-forming region SVA PF05326.6 KFM08376.1 - 5e-09 35.9 0.5 1.3e-08 34.6 0.3 1.7 1 0 0 1 1 1 1 Seminal vesicle autoantigen (SVA) Prenyltrans_2 PF13249.1 KFM08376.1 - 5e-09 36.5 2.1 0.0017 18.7 0.0 3.1 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 KFM08376.1 - 5.9e-07 29.4 0.0 0.0051 16.8 0.0 2.7 2 1 0 2 2 2 2 Prenyltransferase-like Prenyltrans PF00432.16 KFM08376.1 - 0.07 12.7 0.2 13 5.4 0.0 3.3 3 0 0 3 3 3 0 Prenyltransferase and squalene oxidase repeat RimK PF08443.6 KFM08377.1 - 5.8e-43 146.5 0.0 7.6e-43 146.2 0.0 1.1 1 0 0 1 1 1 1 RimK-like ATP-grasp domain GSH-S_ATP PF02955.11 KFM08377.1 - 2.3e-12 46.3 0.0 3.6e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATP-grasp_4 PF13535.1 KFM08377.1 - 7.5e-12 45.3 0.0 1.1e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KFM08377.1 - 5.8e-08 32.7 0.0 8.3e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KFM08377.1 - 1.2e-05 24.2 0.0 2.2e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Synapsin_C PF02750.9 KFM08377.1 - 3.6e-05 22.9 0.0 5.3e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Synapsin, ATP binding domain ATP-grasp PF02222.17 KFM08377.1 - 0.0014 17.9 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KFM08377.1 - 0.0038 16.6 0.0 0.054 12.8 0.0 2.0 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATPgrasp_ST PF14397.1 KFM08377.1 - 0.0086 15.2 0.1 0.53 9.3 0.0 2.4 1 1 0 2 2 2 1 Sugar-transfer associated ATP-grasp CPSase_L_D2 PF02786.12 KFM08377.1 - 0.021 14.0 0.0 0.12 11.6 0.0 2.0 1 1 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain AChE_tetra PF08674.5 KFM08378.1 - 4.5e-21 74.0 6.3 7.1e-21 73.4 4.4 1.3 1 0 0 1 1 1 1 Acetylcholinesterase tetramerisation domain CENP-Q PF13094.1 KFM08381.1 - 0.003 17.6 11.2 0.0039 17.2 7.7 1.2 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit CALCOCO1 PF07888.6 KFM08381.1 - 0.0071 14.6 4.2 0.0087 14.4 2.9 1.0 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like SF-assemblin PF06705.6 KFM08381.1 - 0.055 12.6 6.6 0.074 12.1 4.6 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin Herpes_UL6 PF01763.11 KFM08381.1 - 0.069 11.3 3.6 0.078 11.1 2.5 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like End3 PF12761.2 KFM08381.1 - 0.078 12.6 5.5 0.098 12.2 3.8 1.2 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF4140 PF13600.1 KFM08381.1 - 0.096 13.1 1.8 0.21 12.0 0.3 1.9 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF342 PF03961.8 KFM08381.1 - 0.1 10.9 5.3 0.13 10.6 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4482 PF14818.1 KFM08381.1 - 0.56 10.8 11.3 0.8 10.3 7.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4482) V_ATPase_I PF01496.14 KFM08381.1 - 0.58 7.9 5.1 0.66 7.7 3.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mnd1 PF03962.10 KFM08381.1 - 1.7 8.2 10.2 2 8.0 7.0 1.2 1 0 0 1 1 1 0 Mnd1 family DUF4407 PF14362.1 KFM08381.1 - 1.7 7.5 4.8 1.9 7.3 3.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Microtub_assoc PF07989.6 KFM08381.1 - 1.9 8.3 10.5 1.3 8.9 2.0 2.2 2 0 0 2 2 2 0 Microtubule associated KLRAQ PF10205.4 KFM08381.1 - 3.3 7.7 12.7 0.88 9.6 6.2 1.8 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein C2-set PF05790.10 KFM08381.1 - 5.3 7.0 8.0 10 6.1 4.6 2.0 1 1 1 2 2 2 0 Immunoglobulin C2-set domain YlqD PF11068.3 KFM08381.1 - 5.4 7.0 13.1 9.6 6.2 9.1 1.5 1 1 0 1 1 1 0 YlqD protein Spc24 PF08286.6 KFM08381.1 - 5.7 6.6 10.6 0.68 9.6 2.7 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF1241 PF06840.6 KFM08382.1 - 4.3e-66 220.9 4.4 6.1e-66 220.4 3.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Med11 PF10280.4 KFM08382.1 - 0.0012 18.9 1.8 0.004 17.1 0.4 2.2 1 1 1 2 2 2 1 Mediator complex protein FH2 PF02181.18 KFM08382.1 - 0.0042 16.0 2.6 0.0042 16.0 1.8 1.5 1 1 0 1 1 1 1 Formin Homology 2 Domain BLOC1_2 PF10046.4 KFM08382.1 - 0.0061 16.6 1.3 0.016 15.3 0.3 2.1 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prominin PF05478.6 KFM08382.1 - 0.02 12.4 1.6 0.023 12.2 1.1 1.2 1 0 0 1 1 1 0 Prominin Decorin_bind PF02352.10 KFM08382.1 - 0.048 13.6 2.4 0.5 10.3 0.3 2.4 2 0 0 2 2 2 0 Decorin binding protein Hormone_1 PF00103.15 KFM08382.1 - 0.051 12.9 0.5 0.095 12.0 0.3 1.5 1 0 0 1 1 1 0 Somatotropin hormone family Sec23_trunk PF04811.10 KFM08382.1 - 0.082 12.2 1.3 1.1 8.5 0.2 2.6 1 1 1 2 2 2 0 Sec23/Sec24 trunk domain DUF2852 PF11014.3 KFM08382.1 - 0.2 11.5 1.9 0.37 10.7 1.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2852) DUF4358 PF14270.1 KFM08382.1 - 0.29 11.0 3.2 11 5.9 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4358) Syntaxin_2 PF14523.1 KFM08382.1 - 1.2 9.2 5.7 1.6 8.8 3.1 1.9 1 1 0 1 1 1 0 Syntaxin-like protein Serpin PF00079.15 KFM08383.1 - 2.8e-121 405.1 1.5 3.1e-121 404.9 1.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) LRR_4 PF12799.2 KFM08385.1 - 8.8e-12 44.3 6.9 0.00067 19.2 0.0 4.7 3 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM08385.1 - 3.7e-05 23.3 6.7 0.0042 16.8 0.7 3.5 2 1 2 4 4 4 3 Leucine rich repeat LRR_9 PF14580.1 KFM08385.1 - 0.0041 16.7 0.2 0.016 14.7 0.1 1.9 1 1 1 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.28 KFM08385.1 - 0.0087 15.9 10.4 5.6 7.4 0.1 5.8 4 2 2 6 6 6 1 Leucine Rich Repeat LRR_6 PF13516.1 KFM08385.1 - 0.26 11.4 5.9 26 5.2 0.1 4.8 5 1 1 6 6 6 0 Leucine Rich repeat LRR_7 PF13504.1 KFM08385.1 - 1.1 9.7 10.6 15 6.3 0.0 5.3 8 0 0 8 8 8 0 Leucine rich repeat Amdo_NSP PF12475.3 KFM08386.1 - 0.014 15.3 0.2 0.14 12.1 0.1 2.9 1 0 0 1 1 1 0 Amdovirus non-structural protein DUF4525 PF15027.1 KFM08386.1 - 0.041 13.4 0.6 0.041 13.4 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4525) zf-C2H2 PF00096.21 KFM08387.1 - 2.8e-50 165.6 83.2 7.8e-07 29.0 0.8 10.6 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM08387.1 - 1.7e-34 116.3 75.0 2.9e-09 36.7 0.9 12.1 12 0 0 12 12 12 7 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM08387.1 - 1.7e-29 99.9 70.6 0.00028 21.0 0.8 10.5 10 0 0 10 10 10 10 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM08387.1 - 1.6e-16 59.5 67.4 0.00019 21.1 0.0 10.4 10 0 0 10 10 10 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM08387.1 - 9.3e-13 47.9 56.0 0.0014 18.6 0.4 10.5 10 0 0 10 10 10 6 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 KFM08387.1 - 2.5e-05 23.9 8.3 9.9e-05 22.0 0.7 8.2 4 3 4 8 8 8 3 BED zinc finger GAGA PF09237.6 KFM08387.1 - 0.0056 16.2 19.2 2.1 8.0 0.1 5.7 3 1 2 5 5 5 3 GAGA factor zf-met PF12874.2 KFM08387.1 - 0.27 11.4 48.1 0.55 10.5 0.2 9.4 9 0 0 9 9 9 0 Zinc-finger of C2H2 type BolA PF01722.13 KFM08387.1 - 0.5 10.3 4.6 53 3.8 0.0 4.9 3 3 2 5 5 5 0 BolA-like protein NfI_DNAbd_pre-N PF10524.4 KFM08388.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Nuclear factor I protein pre-N-terminus zf-H2C2_2 PF13465.1 KFM08389.1 - 7.7e-59 193.2 43.5 3.1e-09 36.6 0.1 9.4 9 0 0 9 9 9 7 Zinc-finger double domain zf-C2H2 PF00096.21 KFM08389.1 - 3.6e-37 124.4 53.4 5.1e-06 26.5 0.3 8.8 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM08389.1 - 7e-28 94.8 45.8 0.00047 20.2 1.6 8.6 8 0 0 8 8 8 8 C2H2-type zinc finger BTB PF00651.26 KFM08389.1 - 2.5e-24 85.3 0.2 7.1e-24 83.9 0.1 1.8 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_jaz PF12171.3 KFM08389.1 - 4.1e-14 52.2 31.2 0.026 14.6 0.0 8.6 9 0 0 9 9 8 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFM08389.1 - 3.2e-12 45.8 36.5 0.062 13.2 0.0 8.9 8 1 0 8 8 8 6 C2H2-type zinc finger zf-met PF12874.2 KFM08389.1 - 1.1e-05 25.4 56.2 0.002 18.2 0.3 9.2 10 0 0 10 10 10 4 Zinc-finger of C2H2 type zf-Di19 PF05605.7 KFM08389.1 - 0.00031 20.8 30.4 0.061 13.4 0.4 5.6 4 1 1 5 5 5 4 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.10 KFM08389.1 - 0.0074 16.0 0.4 0.0074 16.0 0.2 7.8 4 2 5 9 9 9 2 BED zinc finger SMN PF06003.7 KFM08389.1 - 0.014 14.4 1.8 0.033 13.2 1.3 1.6 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Zn-ribbon_8 PF09723.5 KFM08389.1 - 0.019 14.8 26.3 8.7 6.3 0.0 7.6 5 1 1 6 6 6 0 Zinc ribbon domain XPA_N PF01286.13 KFM08389.1 - 0.25 11.0 25.1 23 4.7 0.0 7.7 8 0 0 8 8 8 0 XPA protein N-terminal DUF1610 PF07754.6 KFM08389.1 - 0.67 10.1 0.0 0.67 10.1 0.0 6.3 7 0 0 7 7 6 0 Domain of unknown function (DUF1610) C1_4 PF07975.7 KFM08389.1 - 1.2 9.2 30.6 2.8 8.0 4.8 6.1 1 1 7 8 8 8 0 TFIIH C1-like domain RRN7 PF11781.3 KFM08389.1 - 9 5.8 17.5 50 3.4 0.2 6.5 7 0 0 7 7 7 0 RNA polymerase I-specific transcription initiation factor Rrn7 LRR_6 PF13516.1 KFM08390.1 - 7.7e-19 65.6 48.2 0.03 14.3 0.0 14.5 14 1 1 15 15 15 8 Leucine Rich repeat LRR_4 PF12799.2 KFM08390.1 - 1.6e-18 65.8 41.4 0.00098 18.6 0.0 9.7 5 3 6 11 11 11 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM08390.1 - 1.5e-13 48.6 39.2 0.83 9.9 0.0 13.7 12 1 1 13 13 13 6 Leucine Rich Repeat LRR_7 PF13504.1 KFM08390.1 - 1.1e-12 45.9 38.6 2.7 8.5 0.4 14.2 15 0 0 15 15 15 4 Leucine rich repeat LRR_8 PF13855.1 KFM08390.1 - 1.4e-11 43.9 43.0 0.0001 22.0 1.3 8.8 5 2 3 8 8 7 5 Leucine rich repeat PYRIN PF02758.11 KFM08390.1 - 0.0096 15.6 0.2 1 9.0 0.0 2.8 2 0 0 2 2 2 1 PAAD/DAPIN/Pyrin domain DUF2780 PF11075.3 KFM08390.1 - 0.019 15.0 1.9 0.97 9.4 0.1 3.6 2 1 1 3 3 3 0 Protein of unknown function VcgC/VcgE (DUF2780) SAM_1 PF00536.25 KFM08391.1 - 2.1e-12 47.0 0.0 3.9e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFM08391.1 - 2.4e-09 36.9 0.0 4.7e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 KFM08391.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Sec62 PF03839.11 KFM08392.1 - 1.1e-91 306.2 7.4 1.1e-91 306.2 5.2 2.3 2 1 1 3 3 3 1 Translocation protein Sec62 OPT PF03169.10 KFM08392.1 - 0.014 13.8 0.0 0.019 13.3 0.0 1.1 1 0 0 1 1 1 0 OPT oligopeptide transporter protein DEP PF00610.16 KFM08392.1 - 0.044 13.5 0.1 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) BUD22 PF09073.5 KFM08392.1 - 0.097 11.7 51.2 0.13 11.2 10.7 2.1 2 0 0 2 2 2 0 BUD22 Ycf1 PF05758.7 KFM08392.1 - 0.098 10.3 20.0 0.032 11.9 0.3 2.1 2 0 0 2 2 2 0 Ycf1 Ribosomal_S26e PF01283.14 KFM08393.1 - 1.2 9.4 2.7 1.1 9.5 0.1 2.2 2 1 0 2 2 2 0 Ribosomal protein S26e Pkinase PF00069.20 KFM08394.1 - 2.3e-64 217.0 0.0 3e-64 216.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM08394.1 - 2.2e-34 118.7 0.0 3.3e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 KFM08394.1 - 1.3e-14 53.6 9.2 2.6e-14 52.6 6.4 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PB1 PF00564.19 KFM08394.1 - 1.5e-10 40.6 0.0 4e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 PB1 domain Pkinase_C PF00433.19 KFM08394.1 - 7.9e-07 29.4 1.1 1.8e-06 28.3 0.7 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KFM08394.1 - 3.1e-06 26.3 0.0 4.6e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFM08394.1 - 0.01 14.8 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFM08394.1 - 0.029 14.0 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family C1_3 PF07649.7 KFM08394.1 - 0.057 13.4 1.5 0.18 11.8 1.1 1.8 1 0 0 1 1 1 0 C1-like domain c-SKI_SMAD_bind PF08782.5 KFM08395.1 - 4.6e-44 148.4 3.2 4.6e-44 148.4 2.2 2.4 2 0 0 2 2 2 1 c-SKI Smad4 binding domain Ski_Sno PF02437.12 KFM08395.1 - 1.1e-43 147.4 1.1 2.9e-43 146.0 0.7 1.7 1 0 0 1 1 1 1 SKI/SNO/DAC family DUF489 PF04356.7 KFM08395.1 - 0.85 9.1 11.1 0.78 9.3 6.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF489) PMP22_Claudin PF00822.15 KFM08396.1 - 2.3e-20 72.8 11.2 3.2e-20 72.4 7.8 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFM08396.1 - 1.9e-08 34.2 7.3 1.9e-08 34.2 5.1 1.8 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF4233 PF14017.1 KFM08396.1 - 1.8 8.5 7.6 0.22 11.4 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4233) AA_permease_2 PF13520.1 KFM08397.1 - 1.3e-46 158.9 57.3 2.7e-45 154.6 26.9 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.16 KFM08397.1 - 5.8e-37 127.1 38.7 5.8e-37 127.1 26.8 2.4 2 1 0 2 2 2 2 Amino acid permease AA_permease_C PF13906.1 KFM08397.1 - 2.4e-20 72.1 9.8 2.4e-20 72.1 6.8 4.7 5 0 0 5 5 5 1 C-terminus of AA_permease Ribosomal_L22e PF01776.12 KFM08398.1 - 3.3e-48 162.3 3.4 4e-48 162.0 2.4 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family eIF-5a PF01287.15 KFM08399.1 - 6.8e-26 90.0 0.1 9.4e-26 89.5 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 KFM08399.1 - 0.0017 18.0 0.2 0.0029 17.2 0.2 1.4 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 KFM08399.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Sugar_tr PF00083.19 KFM08400.1 - 5.2e-152 506.5 25.8 6.4e-152 506.2 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFM08400.1 - 5.6e-20 71.3 38.0 9.1e-17 60.7 18.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFM08400.1 - 2.9e-10 39.1 27.6 3.1e-09 35.7 5.1 3.3 1 1 1 3 3 3 2 MFS/sugar transport protein CNH PF00780.17 KFM08401.1 - 1.3e-59 201.9 0.0 2e-59 201.2 0.0 1.3 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.20 KFM08401.1 - 2.7e-59 200.4 0.0 2.7e-59 200.4 0.0 2.3 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM08401.1 - 6.6e-44 149.9 0.0 1.2e-43 149.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM08401.1 - 1.8e-05 23.8 0.0 4.7e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Kinase-like HSP70 PF00012.15 KFM08402.1 - 4.9e-267 886.7 10.5 5.5e-267 886.5 7.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFM08402.1 - 2.9e-17 62.2 0.1 6.6e-17 61.0 0.1 1.5 1 1 0 1 1 1 1 MreB/Mbl protein Hydantoinase_A PF01968.13 KFM08402.1 - 3.4e-05 23.1 1.2 0.0013 17.8 0.1 2.7 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase DDR PF08841.5 KFM08402.1 - 0.0095 14.8 1.1 0.12 11.1 0.5 2.3 1 1 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.11 KFM08402.1 - 0.032 13.8 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Kelch_3 PF13415.1 KFM08403.1 - 1.3e-29 101.6 7.8 8.4e-09 35.3 0.0 5.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_4 PF13418.1 KFM08403.1 - 6.3e-25 86.6 10.4 1.6e-08 34.2 0.0 4.9 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.20 KFM08403.1 - 2.3e-24 84.6 0.6 1.6e-08 33.9 0.0 4.4 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 KFM08403.1 - 5.6e-24 83.2 1.7 1.1e-07 31.7 0.0 3.6 2 1 2 4 4 4 3 Kelch motif Kelch_5 PF13854.1 KFM08403.1 - 5.7e-20 70.8 7.2 3.3e-06 26.9 0.1 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.10 KFM08403.1 - 2.4e-15 55.6 3.4 9.1e-06 25.2 0.0 4.6 4 1 0 4 4 4 3 Kelch motif PQQ_3 PF13570.1 KFM08403.1 - 0.15 12.3 3.6 7.3 7.0 0.0 3.7 4 0 0 4 4 4 0 PQQ-like domain Metallophos PF00149.23 KFM08404.1 - 3.2e-30 105.0 0.1 4.3e-30 104.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase P16-Arc PF04699.9 KFM08405.1 - 1e-29 103.4 0.0 1.1e-29 103.3 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.7 KFM08405.1 - 0.0041 17.0 0.0 0.0062 16.4 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family TPX2_importin PF12214.3 KFM08405.1 - 0.059 13.4 0.0 0.067 13.2 0.0 1.1 1 0 0 1 1 1 0 Cell cycle regulated microtubule associated protein GRIP PF01465.15 KFM08406.1 - 7.5e-15 54.1 0.9 2.7e-14 52.4 0.6 2.1 1 0 0 1 1 1 1 GRIP domain DUF3550 PF12070.3 KFM08407.1 - 2.2e-255 848.2 4.4 2.5e-255 848.0 3.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3550/UPF0682) Ribosomal_L29 PF00831.18 KFM08408.1 - 0.00036 20.1 0.9 0.00036 20.1 0.6 2.5 2 1 0 2 2 2 1 Ribosomal L29 protein XFP_N PF09364.5 KFM08408.1 - 0.036 12.6 0.0 0.037 12.5 0.0 1.0 1 0 0 1 1 1 0 XFP N-terminal domain OmpH PF03938.9 KFM08408.1 - 0.092 12.6 1.7 0.1 12.4 1.2 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2830 PF11125.3 KFM08408.1 - 0.16 11.6 0.1 0.26 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2830) HTH_12 PF08461.5 KFM08408.1 - 0.34 10.6 2.5 0.3 10.8 0.9 1.5 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain Orbi_VP1 PF05788.7 KFM08408.1 - 1.8 5.6 5.0 2 5.4 3.5 1.0 1 0 0 1 1 1 0 Orbivirus RNA-dependent RNA polymerase (VP1) OLF PF02191.11 KFM08409.1 - 1.6e-90 302.7 4.5 1.6e-90 302.7 3.1 1.8 2 0 0 2 2 2 1 Olfactomedin-like domain CENP-K PF11802.3 KFM08409.1 - 0.0049 16.1 2.3 0.0073 15.5 1.6 1.1 1 0 0 1 1 1 1 Centromere-associated protein K Noelin-1 PF12308.3 KFM08409.1 - 0.0063 16.2 4.0 0.033 13.9 0.1 2.4 1 1 1 2 2 2 1 Neurogenesis glycoprotein zf-C4 PF00105.13 KFM08410.1 - 3.1e-28 97.8 17.9 7.6e-28 96.5 12.4 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 KFM08410.1 - 4.5e-28 97.7 4.6 8.9e-28 96.8 3.2 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor 7tm_2 PF00002.19 KFM08411.1 - 2.8e-48 164.1 24.7 5.1e-48 163.2 17.1 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Pentaxin PF00354.12 KFM08411.1 - 6.2e-29 100.8 0.1 1.1e-28 99.9 0.1 1.4 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.1 KFM08411.1 - 3.5e-15 56.5 0.1 6.1e-15 55.8 0.1 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily GPS PF01825.16 KFM08411.1 - 1.5e-09 37.8 1.8 1.5e-09 37.8 1.2 3.0 3 0 0 3 3 3 1 Latrophilin/CL-1-like GPS domain Dicty_CAR PF05462.6 KFM08411.1 - 1.6e-05 23.9 10.6 2.8e-05 23.1 7.4 1.4 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Tex_N PF09371.5 KFM08411.1 - 0.00061 19.1 0.0 0.0015 17.9 0.0 1.5 1 0 0 1 1 1 1 Tex-like protein N-terminal domain DUF3497 PF12003.3 KFM08411.1 - 0.0013 18.1 0.7 0.0023 17.3 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3497) Lectin_C PF00059.16 KFM08411.1 - 0.002 18.7 2.0 0.23 12.1 0.0 3.2 3 0 0 3 3 3 1 Lectin C-type domain Laminin_G_2 PF02210.19 KFM08411.1 - 0.0033 17.4 0.0 0.0075 16.3 0.0 1.6 1 0 0 1 1 1 1 Laminin G domain Pox_P21 PF05313.7 KFM08411.1 - 8.5 5.5 12.3 0.29 10.3 2.0 2.4 2 0 0 2 2 2 0 Poxvirus P21 membrane protein Proteasome PF00227.21 KFM08412.1 - 1.6e-45 154.7 0.0 2e-45 154.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 KFM08412.1 - 6.4e-14 50.9 0.1 1.7e-13 49.5 0.1 1.8 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Pkinase PF00069.20 KFM08413.1 - 3.8e-66 222.9 0.0 4.6e-66 222.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM08413.1 - 7.2e-47 159.6 0.0 8.6e-47 159.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM08413.1 - 1e-05 24.6 0.0 1.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFM08413.1 - 0.0081 15.2 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DENN PF02141.16 KFM08414.1 - 3.6e-47 160.4 1.9 3.6e-47 160.4 1.3 1.9 2 0 0 2 2 2 1 DENN (AEX-3) domain dDENN PF03455.14 KFM08414.1 - 4.5e-17 61.8 0.2 9.6e-17 60.8 0.2 1.6 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.13 KFM08414.1 - 1.9e-16 59.7 1.1 5.5e-16 58.2 0.7 1.8 1 0 0 1 1 1 1 uDENN domain EGF PF00008.22 KFM08415.1 - 1.7e-93 305.8 251.6 7.2e-10 38.6 7.2 19.8 19 2 0 19 19 19 17 EGF-like domain Laminin_G_2 PF02210.19 KFM08415.1 - 2.9e-43 146.9 0.5 6.1e-18 65.0 0.0 4.4 3 1 0 3 3 3 3 Laminin G domain Laminin_G_1 PF00054.18 KFM08415.1 - 1.2e-26 93.2 0.0 1.5e-12 47.6 0.0 4.2 3 1 0 3 3 3 3 Laminin G domain EGF_2 PF07974.8 KFM08415.1 - 1.4e-13 50.7 284.7 0.0024 18.0 5.2 18.7 17 1 1 18 18 18 13 EGF-like domain EGF_CA PF07645.10 KFM08415.1 - 3.8e-11 42.7 263.2 9.9e-05 22.2 4.6 19.6 13 4 6 19 19 19 12 Calcium-binding EGF domain hEGF PF12661.2 KFM08415.1 - 1.7e-06 27.6 155.6 0.00081 19.3 2.5 17.6 17 0 0 17 17 17 10 Human growth factor-like EGF Laminin_G_3 PF13385.1 KFM08415.1 - 0.00072 19.8 0.0 9.1 6.4 0.0 3.4 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily DZF PF07528.9 KFM08417.1 - 3.1e-79 265.8 0.0 4.8e-79 265.2 0.0 1.3 1 0 0 1 1 1 1 DZF domain dsrm PF00035.20 KFM08417.1 - 1.1e-27 96.3 0.0 2.4e-14 53.6 0.0 2.7 2 0 0 2 2 2 2 Double-stranded RNA binding motif DND1_DSRM PF14709.1 KFM08417.1 - 1e-06 28.9 0.3 0.11 12.8 0.0 3.3 3 0 0 3 3 3 2 double strand RNA binding domain from DEAD END PROTEIN 1 RabGAP-TBC PF00566.13 KFM08418.1 - 5.9e-57 192.5 2.0 5.9e-57 192.5 1.4 2.4 3 0 0 3 3 3 1 Rab-GTPase-TBC domain DUF3694 PF12473.3 KFM08418.1 - 2.3e-35 121.2 0.0 6.7e-35 119.7 0.0 1.9 1 0 0 1 1 1 1 Kinesin protein PID PF00640.18 KFM08418.1 - 1e-06 28.8 2.2 5.7e-06 26.3 0.0 3.0 3 1 0 3 3 3 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.8 KFM08418.1 - 0.0019 18.1 0.0 0.0066 16.3 0.0 2.0 1 0 0 1 1 1 1 Phosphotyrosine-binding domain BTB PF00651.26 KFM08419.1 - 3.4e-18 65.6 0.4 1e-17 64.1 0.1 2.0 2 0 0 2 2 2 1 BTB/POZ domain zf-C2H2 PF00096.21 KFM08419.1 - 4.9e-18 64.3 39.2 9.6e-06 25.6 1.8 5.3 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM08419.1 - 1.2e-17 63.2 23.6 1.8e-07 31.1 0.4 5.8 4 1 1 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM08419.1 - 3.1e-15 55.2 32.2 0.00028 21.0 0.5 5.2 5 0 0 5 5 5 4 C2H2-type zinc finger DUF899 PF05988.7 KFM08419.1 - 0.00045 19.7 1.3 0.00073 19.0 0.1 1.8 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF899) zf-C2H2_6 PF13912.1 KFM08419.1 - 0.00074 19.3 24.5 0.68 9.9 2.5 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.2 KFM08419.1 - 0.0025 17.9 25.1 0.034 14.3 1.9 4.6 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFM08419.1 - 0.0026 17.8 19.1 0.35 11.0 0.1 4.8 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFM08419.1 - 0.006 16.6 26.3 0.26 11.4 0.6 5.3 1 1 4 5 5 5 3 C2H2 type zinc-finger (2 copies) PyrI_C PF02748.10 KFM08419.1 - 0.082 12.3 4.1 1.1 8.7 0.0 3.3 2 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-CHCC PF10276.4 KFM08419.1 - 0.16 11.7 0.1 0.16 11.7 0.0 2.9 4 0 0 4 4 4 0 Zinc-finger domain GAGA PF09237.6 KFM08419.1 - 0.35 10.4 8.3 23 4.7 0.0 4.2 1 1 3 4 4 4 0 GAGA factor zf-BED PF02892.10 KFM08419.1 - 3.8 7.3 26.8 4.9 6.9 2.0 4.3 2 2 2 4 4 4 0 BED zinc finger zf-LYAR PF08790.6 KFM08419.1 - 7.2 6.4 9.4 29 4.4 0.1 3.9 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger C1_1 PF00130.17 KFM08419.1 - 8.6 6.1 17.6 28 4.5 0.2 3.5 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) BTB PF00651.26 KFM08420.1 - 4.8e-20 71.6 2.2 4.8e-20 71.6 1.5 2.0 2 0 0 2 2 2 1 BTB/POZ domain zf-C2H2 PF00096.21 KFM08420.1 - 1.9e-16 59.3 34.3 4.5e-05 23.5 0.8 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM08420.1 - 1.3e-13 50.4 23.9 4.3e-07 29.8 0.0 5.0 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM08420.1 - 1.9e-10 40.3 27.9 0.0011 19.1 0.3 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 KFM08420.1 - 3.3e-05 23.9 24.2 0.0027 17.8 0.5 4.0 4 0 0 4 4 3 3 Zinc-finger of C2H2 type Chordopox_E11 PF06138.7 KFM08420.1 - 0.005 16.9 0.3 0.1 12.6 0.0 2.3 2 0 0 2 2 2 1 Chordopoxvirus E11 protein zf-C2H2_2 PF12756.2 KFM08420.1 - 0.037 14.1 20.9 0.42 10.7 5.9 4.2 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KFM08420.1 - 0.049 13.7 23.2 0.76 10.0 3.2 5.0 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 KFM08420.1 - 0.2 11.4 22.5 1.9 8.3 0.1 4.1 3 1 1 4 4 4 0 BED zinc finger zf-LYAR PF08790.6 KFM08420.1 - 0.26 11.0 0.1 0.26 11.0 0.1 3.7 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger zf-UBP PF02148.14 KFM08420.1 - 0.71 10.0 10.3 7.8 6.6 7.2 2.5 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-H2C2_5 PF13909.1 KFM08420.1 - 1.6 9.1 28.3 1 9.7 0.2 5.3 4 1 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 KFM08420.1 - 2.8 7.9 22.9 1.9 8.5 0.6 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger ROS_MUCR PF05443.6 KFM08420.1 - 3.4 7.4 5.2 2.1 8.1 0.2 2.8 2 1 0 2 2 2 0 ROS/MUCR transcriptional regulator protein zf-CCCH PF00642.19 KFM08421.1 - 1.6e-07 30.8 2.0 1.6e-07 30.8 1.4 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_5 PF14634.1 KFM08421.1 - 4.8e-06 26.2 8.0 1.2e-05 24.8 5.6 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KFM08421.1 - 1.2e-05 25.0 6.8 4e-05 23.3 4.7 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFM08421.1 - 3.6e-05 23.6 7.6 3.6e-05 23.6 5.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM08421.1 - 8.7e-05 22.1 4.6 8.7e-05 22.1 3.2 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFM08421.1 - 0.00035 20.2 6.4 0.00035 20.2 4.4 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KFM08421.1 - 0.00065 19.5 6.2 0.00065 19.5 4.3 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KFM08421.1 - 0.0022 17.6 8.4 0.0058 16.2 5.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Citrate_synt PF00285.16 KFM08421.1 - 0.0041 15.8 0.0 0.0069 15.1 0.0 1.2 1 0 0 1 1 1 1 Citrate synthase Xin PF08043.7 KFM08421.1 - 0.0081 15.7 0.0 0.023 14.3 0.0 1.9 1 0 0 1 1 1 1 Xin repeat Prok-RING_4 PF14447.1 KFM08421.1 - 0.31 10.6 8.8 0.1 12.1 0.9 2.9 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 KFM08421.1 - 1 9.0 5.5 2.2 7.9 3.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Phosducin PF02114.11 KFM08422.1 - 2.4e-32 111.7 3.3 2.5e-32 111.6 2.3 1.0 1 0 0 1 1 1 1 Phosducin CCDC66 PF15236.1 KFM08422.1 - 0.0066 16.0 10.0 0.0077 15.8 7.0 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 66 DUF148 PF02520.12 KFM08422.1 - 0.048 13.4 1.4 0.071 12.8 0.9 1.3 1 1 0 1 1 1 0 Domain of unknown function DUF148 DUF4253 PF14062.1 KFM08422.1 - 0.12 12.0 0.1 0.13 11.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4253) DUF1517 PF07466.6 KFM08422.1 - 0.12 11.3 1.3 0.13 11.2 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) TMEM247 PF15444.1 KFM08422.1 - 0.13 12.0 0.8 0.14 11.9 0.6 1.0 1 0 0 1 1 1 0 Transmembrane protein 247 Toxin_44 PF15523.1 KFM08422.1 - 0.29 11.0 2.5 0.38 10.6 1.7 1.1 1 0 0 1 1 1 0 Putative toxin 44 OmpH PF03938.9 KFM08422.1 - 1.1 9.1 6.1 1.4 8.8 4.2 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FlxA PF14282.1 KFM08422.1 - 8.6 6.3 10.6 43 4.1 7.6 1.6 1 1 0 1 1 1 0 FlxA-like protein An_peroxidase PF03098.10 KFM08423.1 - 1.8e-96 323.6 0.0 5.7e-80 269.2 0.0 2.2 1 1 1 2 2 2 2 Animal haem peroxidase EGF PF00008.22 KFM08423.1 - 0.011 15.7 11.7 0.023 14.6 8.1 1.6 1 0 0 1 1 1 0 EGF-like domain RRF PF01765.14 KFM08424.1 - 1.3e-41 141.8 5.5 1.9e-41 141.2 3.8 1.2 1 0 0 1 1 1 1 Ribosome recycling factor Robl_LC7 PF03259.12 KFM08424.1 - 0.046 13.2 0.2 5.8 6.5 0.0 2.7 3 0 0 3 3 3 0 Roadblock/LC7 domain DUF883 PF05957.8 KFM08424.1 - 0.38 11.1 8.0 0.12 12.7 2.6 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) RRM_5 PF13893.1 KFM08425.1 - 6.7e-13 48.2 0.1 9.5e-13 47.7 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFM08425.1 - 7.5e-12 44.7 0.1 1.2e-11 44.0 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM08425.1 - 8.7e-09 35.2 0.1 1.4e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3446 PF11928.3 KFM08425.1 - 0.093 12.9 1.9 0.14 12.4 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) Y_Y_Y PF07495.8 KFM08426.1 - 0.082 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Y_Y_Y domain CHCH PF06747.8 KFM08427.1 - 4.7e-08 32.7 1.1 6.2e-08 32.3 0.8 1.2 1 0 0 1 1 1 1 CHCH domain COX6B PF02297.12 KFM08427.1 - 0.027 14.4 1.9 0.036 14.0 1.3 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb UCR_hinge PF02320.11 KFM08427.1 - 0.042 13.7 1.9 0.16 11.8 0.1 2.1 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein Cmc1 PF08583.5 KFM08427.1 - 0.095 12.4 0.7 0.13 12.0 0.5 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like TTL PF03133.10 KFM08430.1 - 8.5e-67 225.1 0.0 1.3e-66 224.5 0.0 1.3 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 KFM08430.1 - 0.00081 18.2 0.0 0.039 12.7 0.0 2.3 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATP-grasp_3 PF02655.9 KFM08430.1 - 0.0063 16.3 0.0 0.27 11.0 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.6 KFM08430.1 - 0.0088 15.5 0.0 2.7 7.4 0.0 2.3 2 0 0 2 2 2 2 RimK-like ATP-grasp domain Band_7 PF01145.20 KFM08431.1 - 2.7e-37 128.3 0.7 3.3e-37 128.1 0.5 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 KFM08431.1 - 0.0031 17.0 0.2 0.0048 16.4 0.1 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family DUF940 PF06082.6 KFM08431.1 - 0.63 8.5 3.0 0.74 8.2 2.1 1.1 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) Gelsolin PF00626.17 KFM08432.1 - 4.9e-110 359.3 0.2 9.8e-21 73.2 0.0 6.2 6 0 0 6 6 6 6 Gelsolin repeat CutA1 PF03091.10 KFM08432.1 - 0.22 11.2 0.1 3.5 7.3 0.0 2.6 2 0 0 2 2 2 0 CutA1 divalent ion tolerance protein Ras PF00071.17 KFM08433.1 - 6.7e-61 204.4 0.1 7.8e-61 204.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM08433.1 - 2.1e-19 70.1 0.0 3.2e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM08433.1 - 1.4e-12 47.2 0.0 1.8e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFM08433.1 - 5.2e-06 26.0 0.0 0.00012 21.6 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFM08433.1 - 6.6e-06 26.0 0.0 8.4e-06 25.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFM08433.1 - 0.00015 21.0 0.0 0.00018 20.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 KFM08433.1 - 0.0029 17.1 0.0 0.093 12.2 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 KFM08433.1 - 0.024 14.7 0.1 0.056 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KFM08433.1 - 0.027 14.0 0.0 0.049 13.2 0.0 1.5 1 1 1 2 2 2 0 AAA domain SRPRB PF09439.5 KFM08433.1 - 0.046 12.9 0.0 0.066 12.4 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA PF00004.24 KFM08433.1 - 0.071 13.3 0.0 0.38 10.9 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.13 KFM08433.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Septin DUF1863 PF08937.6 KFM08433.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.5 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) LRR_4 PF12799.2 KFM08434.1 - 7.1e-18 63.8 30.6 2.3e-08 33.4 0.5 7.1 3 1 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM08434.1 - 8.9e-16 57.4 31.0 1.6e-09 37.3 5.2 4.5 3 1 2 5 5 5 3 Leucine rich repeat LRR_9 PF14580.1 KFM08434.1 - 4.4e-15 55.6 3.2 2.7e-14 53.1 2.2 2.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.28 KFM08434.1 - 6e-09 34.7 13.2 0.24 11.5 0.2 6.8 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 KFM08434.1 - 0.00055 19.7 13.2 2.6 8.6 0.0 7.3 7 0 0 7 7 7 2 Leucine rich repeat LRR_6 PF13516.1 KFM08434.1 - 0.00083 19.1 16.5 0.052 13.6 0.4 6.0 5 1 1 6 6 6 2 Leucine Rich repeat MATH PF00917.21 KFM08435.1 - 4.7e-24 84.9 0.0 8.8e-24 84.0 0.0 1.5 1 0 0 1 1 1 1 MATH domain zf-TRAF PF02176.13 KFM08435.1 - 3.3e-07 30.5 5.1 3.3e-07 30.5 3.5 3.6 4 0 0 4 4 4 2 TRAF-type zinc finger zf-C3HC4 PF00097.20 KFM08435.1 - 0.0005 19.6 10.8 0.0005 19.6 7.5 3.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF641 PF04859.7 KFM08435.1 - 0.024 14.3 0.3 0.1 12.3 0.1 1.9 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Tnp_zf-ribbon_2 PF13842.1 KFM08435.1 - 0.35 11.3 14.9 0.34 11.3 2.0 3.6 3 0 0 3 3 3 0 DDE_Tnp_1-like zinc-ribbon zf-RING_6 PF14835.1 KFM08435.1 - 0.54 10.0 12.6 0.062 13.1 2.2 2.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 KFM08435.1 - 3.2 7.6 19.5 0.027 14.3 5.1 3.3 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING PHD PF00628.24 KFM08436.1 - 8.4e-14 50.9 18.3 3.5e-08 32.9 1.3 2.5 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.1 KFM08436.1 - 0.00014 21.0 4.0 0.00014 21.0 2.8 3.8 3 2 0 3 3 3 1 PHD-finger Prok-RING_1 PF14446.1 KFM08436.1 - 0.0016 18.1 0.9 0.0016 18.1 0.6 3.1 4 0 0 4 4 4 1 Prokaryotic RING finger family 1 DUF4537 PF15057.1 KFM08436.1 - 0.0032 17.2 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) C1_1 PF00130.17 KFM08436.1 - 0.026 14.2 0.5 0.026 14.2 0.3 4.0 3 1 1 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-rbx1 PF12678.2 KFM08436.1 - 6.7 6.8 11.0 4.6 7.4 0.4 2.6 2 0 0 2 2 2 0 RING-H2 zinc finger Mtf2_C PF14061.1 KFM08437.1 - 1.2e-29 101.9 0.1 2.1e-29 101.1 0.0 1.4 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 Chromo PF00385.19 KFM08437.1 - 0.042 13.5 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain CutA1 PF03091.10 KFM08438.1 - 2.1e-30 104.3 0.1 2.5e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein Proteasom_PSMB PF10508.4 KFM08439.1 - 5.4e-170 565.9 0.0 6e-170 565.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit HEAT_2 PF13646.1 KFM08439.1 - 2.2e-05 24.6 0.0 0.052 13.8 0.0 3.8 2 2 1 3 3 3 1 HEAT repeats RICTOR_V PF14668.1 KFM08439.1 - 0.0029 17.4 0.2 17 5.4 0.0 3.8 2 1 2 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 DUF3554 PF12074.3 KFM08439.1 - 0.0049 16.3 0.7 0.96 8.8 0.0 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF3554) Neurochondrin PF05536.6 KFM08439.1 - 0.015 13.6 0.7 0.77 7.9 0.0 2.5 1 1 0 2 2 2 0 Neurochondrin V-ATPase_H_C PF11698.3 KFM08439.1 - 0.022 14.6 0.2 2.3 8.1 0.0 3.0 3 0 0 3 3 3 0 V-ATPase subunit H CLAMP PF14769.1 KFM08439.1 - 0.055 13.6 0.0 0.28 11.3 0.0 2.2 2 0 0 2 2 2 0 Flagellar C1a complex subunit C1a-32 Galactosyl_T PF01762.16 KFM08440.1 - 2e-39 135.1 0.0 2.6e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.11 KFM08440.1 - 1.5e-06 27.5 0.0 3.2e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 Fringe-like CH PF00307.26 KFM08441.1 - 4.1e-33 113.6 0.3 1.1e-32 112.2 0.2 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFM08441.1 - 2.6e-32 110.3 0.2 6e-32 109.1 0.1 1.7 1 0 0 1 1 1 1 CAMSAP CH domain CAMSAP_CKK PF08683.6 KFM08441.1 - 3.2e-12 46.2 0.1 7e-12 45.1 0.1 1.6 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated UBA PF00627.26 KFM08442.1 - 1.9e-16 59.3 0.7 6.1e-08 32.2 0.0 2.4 2 0 0 2 2 2 2 UBA/TS-N domain UBA_3 PF09288.5 KFM08442.1 - 0.0059 16.1 0.1 1.1 8.9 0.0 3.0 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain HBS1_N PF08938.5 KFM08442.1 - 0.21 11.7 1.3 1.1 9.3 0.0 2.7 3 0 0 3 3 3 0 HBS1 N-terminus BTB PF00651.26 KFM08443.1 - 2.4e-23 82.2 0.0 4.2e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BEN PF10523.4 KFM08443.1 - 2.9e-10 40.0 0.6 8.7e-10 38.5 0.1 2.0 3 0 0 3 3 3 1 BEN domain Evr1_Alr PF04777.8 KFM08444.1 - 2.2e-26 91.5 0.1 5.9e-26 90.2 0.1 1.8 1 0 0 1 1 1 1 Erv1 / Alr family Sep15_SelM PF08806.6 KFM08444.1 - 0.00028 20.5 0.2 0.0016 18.1 0.0 2.3 2 0 0 2 2 2 1 Sep15/SelM redox domain Thioredoxin PF00085.15 KFM08444.1 - 0.0017 18.0 0.0 0.013 15.2 0.0 2.4 3 0 0 3 3 3 1 Thioredoxin SIP1 PF04938.7 KFM08444.1 - 0.13 11.5 1.3 0.2 10.9 0.3 1.7 2 0 0 2 2 2 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) Toxin-deaminase PF14424.1 KFM08444.1 - 0.32 10.9 4.1 0.075 13.0 0.4 1.7 2 0 0 2 2 2 0 The BURPS668_1122 family of deaminases Zn-ribbon_8 PF09723.5 KFM08444.1 - 0.44 10.5 2.6 9.3 6.3 0.2 2.7 2 0 0 2 2 2 0 Zinc ribbon domain DUF35_N PF12172.3 KFM08444.1 - 6.3 6.8 6.2 0.42 10.5 0.5 1.9 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Baculo_FP PF03258.9 KFM08446.1 - 0.032 13.3 0.1 0.043 12.9 0.1 1.2 1 0 0 1 1 1 0 Baculovirus FP protein vATP-synt_E PF01991.13 KFM08446.1 - 2 7.6 10.4 0.91 8.7 5.7 1.5 1 1 0 1 1 1 0 ATP synthase (E/31 kDa) subunit KxDL PF10241.4 KFM08446.1 - 2.3 8.1 9.4 0.47 10.3 3.9 1.9 2 1 0 2 2 2 0 Uncharacterized conserved protein TPR_12 PF13424.1 KFM08447.1 - 4e-54 180.4 54.6 9.2e-11 41.5 0.4 6.2 3 2 6 9 9 8 8 Tetratricopeptide repeat GoLoco PF02188.12 KFM08447.1 - 4.1e-42 140.6 23.9 9.5e-11 40.7 0.3 4.7 4 0 0 4 4 4 4 GoLoco motif TPR_1 PF00515.23 KFM08447.1 - 8.7e-36 120.0 29.1 1.6e-05 24.3 0.0 8.8 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_7 PF13176.1 KFM08447.1 - 3.6e-29 98.2 18.1 1.4e-05 24.5 0.2 8.8 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_11 PF13414.1 KFM08447.1 - 1.3e-21 75.9 25.8 1.1e-06 28.1 0.8 6.2 5 1 1 7 7 7 6 TPR repeat TPR_2 PF07719.12 KFM08447.1 - 1e-20 71.8 31.2 0.0016 18.2 0.1 9.0 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.1 KFM08447.1 - 5.8e-16 57.0 24.2 0.0014 18.2 0.1 8.3 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_10 PF13374.1 KFM08447.1 - 2.4e-15 55.8 16.7 0.073 13.0 0.0 8.8 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.1 KFM08447.1 - 2e-08 34.1 6.4 14 6.6 0.0 7.7 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFM08447.1 - 2.1e-06 28.2 16.1 0.053 14.2 0.1 6.1 2 2 5 7 7 7 5 Tetratricopeptide repeat TPR_4 PF07721.9 KFM08447.1 - 2.4e-06 27.4 0.5 14 6.4 0.0 6.3 6 0 0 6 6 5 0 Tetratricopeptide repeat Rapsyn_N PF10579.4 KFM08447.1 - 1.5e-05 24.7 1.3 0.77 9.6 0.0 4.6 3 3 2 5 5 5 2 Rapsyn N-terminal myristoylation and linker region TPR_17 PF13431.1 KFM08447.1 - 0.00023 21.0 16.5 3.1 8.2 0.0 7.2 6 1 1 7 7 7 1 Tetratricopeptide repeat Apc3 PF12895.2 KFM08447.1 - 0.0011 19.0 16.1 0.52 10.4 0.9 5.2 2 2 4 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 UreE_C PF05194.7 KFM08447.1 - 0.0047 17.0 1.9 1 9.5 0.2 3.6 3 1 1 4 4 4 1 UreE urease accessory protein, C-terminal domain TPR_6 PF13174.1 KFM08447.1 - 0.0055 17.0 6.5 1.5e+02 3.1 0.0 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat FliJ PF02050.11 KFM08447.1 - 0.31 11.1 5.5 1.3 9.1 0.2 3.7 2 2 3 5 5 5 0 Flagellar FliJ protein zf-DNL PF05180.7 KFM08448.1 - 9.3e-31 105.3 0.3 1.1e-30 105.0 0.2 1.1 1 0 0 1 1 1 1 DNL zinc finger Ribosomal_S27e PF01667.12 KFM08448.1 - 0.14 11.7 0.1 0.14 11.7 0.1 2.1 3 0 0 3 3 3 0 Ribosomal protein S27 TRM PF02005.11 KFM08448.1 - 0.14 11.0 0.0 0.16 10.8 0.0 1.0 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase DUF3797 PF12677.2 KFM08448.1 - 0.25 10.9 1.3 0.34 10.5 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) TFIIS_C PF01096.13 KFM08448.1 - 0.46 10.1 3.8 7.3 6.3 0.1 2.4 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.2 KFM08448.1 - 3.9 7.3 5.1 4.7 7.0 0.3 2.3 1 1 0 2 2 2 0 Transposase zinc-ribbon domain zf-ISL3 PF14690.1 KFM08448.1 - 5.7 7.0 5.9 5.6 7.0 0.9 2.3 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zinc_ribbon_4 PF13717.1 KFM08448.1 - 9.9 5.9 7.7 6.9 6.4 3.1 2.3 2 1 0 2 2 2 0 zinc-ribbon domain Myb_DNA-binding PF00249.26 KFM08449.1 - 3.4e-50 167.8 15.3 2.3e-14 53.1 0.7 6.1 5 0 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFM08449.1 - 2.3e-43 146.1 30.4 1.6e-13 50.5 1.0 5.9 1 1 4 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.6 KFM08449.1 - 0.0098 15.6 0.3 1.2 8.9 0.1 3.1 2 1 0 2 2 2 1 Rap1 Myb domain Rap1_C PF11626.3 KFM08449.1 - 0.041 13.7 0.1 0.041 13.7 0.0 3.2 2 1 2 4 4 4 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain ERM PF00769.14 KFM08450.1 - 1e-05 25.2 15.3 1.3e-05 24.9 10.6 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF724 PF05266.9 KFM08450.1 - 0.0059 16.2 13.3 0.0078 15.8 9.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF724) DUF3781 PF12636.2 KFM08450.1 - 0.039 13.9 0.3 0.089 12.7 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) ART PF01129.13 KFM08450.1 - 0.073 12.1 1.8 0.091 11.8 1.2 1.1 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase GAS PF13851.1 KFM08450.1 - 0.098 11.8 21.9 0.13 11.4 4.5 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4410 PF14366.1 KFM08450.1 - 0.1 12.3 2.6 0.14 11.9 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4410) Tropomyosin PF00261.15 KFM08450.1 - 0.11 11.5 18.8 0.19 10.8 12.7 1.7 1 1 0 1 1 1 0 Tropomyosin V_ATPase_I PF01496.14 KFM08450.1 - 0.14 10.0 10.8 0.14 9.9 7.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-O PF09496.5 KFM08450.1 - 0.18 12.0 1.1 0.43 10.8 0.8 1.7 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component LNP1 PF15419.1 KFM08450.1 - 0.48 10.5 5.9 0.79 9.7 4.1 1.5 1 1 0 1 1 1 0 Leukemia NUP98 fusion partner 1 Peptidase_S46 PF10459.4 KFM08450.1 - 0.62 8.4 8.7 0.71 8.2 6.0 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF4518 PF15008.1 KFM08450.1 - 0.63 9.0 7.3 0.81 8.6 5.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4518) FUSC PF04632.7 KFM08450.1 - 0.84 7.9 3.2 0.92 7.8 2.2 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2514 PF10721.4 KFM08450.1 - 0.91 9.1 14.5 3 7.5 8.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2514) Sipho_Gp157 PF05565.6 KFM08450.1 - 1.2 8.7 13.5 4.1 6.9 8.7 1.9 1 1 1 2 2 2 0 Siphovirus Gp157 DUF3718 PF12514.3 KFM08450.1 - 1.3 9.1 6.5 5.6 7.1 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3718) DUF2630 PF10944.3 KFM08450.1 - 1.3 9.1 8.1 1.7 8.8 0.5 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2630) DUF972 PF06156.8 KFM08450.1 - 3.1 8.2 18.9 0.53 10.6 5.5 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Peptidase_M16_C PF05193.16 KFM08451.1 - 2.8e-40 137.9 0.0 5.4e-40 137.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KFM08451.1 - 4.6e-36 123.8 0.0 1.2e-35 122.4 0.0 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) DUF2695 PF10905.3 KFM08451.1 - 0.046 13.4 0.1 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2695) Exo_endo_phos PF03372.18 KFM08452.1 - 9.9e-21 74.8 0.3 1.4e-20 74.3 0.2 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Sec16_C PF12931.2 KFM08453.1 - 4.7e-37 128.2 0.0 7.9e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 KFM08453.1 - 6e-19 68.1 0.0 1.8e-18 66.6 0.0 1.9 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Ank_2 PF12796.2 KFM08454.1 - 6.3e-58 193.1 28.8 1.8e-15 57.0 0.8 3.9 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KFM08454.1 - 3.8e-45 149.4 11.4 2.4e-08 33.3 0.0 7.1 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 KFM08454.1 - 8.6e-28 95.7 9.5 7.4e-10 38.7 0.1 5.2 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM08454.1 - 1.3e-26 89.9 3.8 3.7e-05 23.5 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 KFM08454.1 - 3.5e-21 75.1 9.8 7.9e-09 35.7 0.1 4.6 2 1 4 6 6 6 4 Ankyrin repeats (many copies) EGF PF00008.22 KFM08455.1 - 2.1e-109 356.7 236.4 9.6e-10 38.2 5.4 15.3 15 0 0 15 15 15 15 EGF-like domain EGF_CA PF07645.10 KFM08455.1 - 4.1e-49 164.3 235.6 7.3e-08 32.2 7.1 15.2 9 4 6 15 15 15 15 Calcium-binding EGF domain hEGF PF12661.2 KFM08455.1 - 7.6e-27 91.5 153.2 0.0011 18.9 4.2 16.6 16 0 0 16 16 16 12 Human growth factor-like EGF EGF_2 PF07974.8 KFM08455.1 - 1.6e-25 88.8 260.0 0.0011 19.0 6.8 15.4 14 1 1 15 15 15 15 EGF-like domain FXa_inhibition PF14670.1 KFM08455.1 - 4.3e-09 36.3 207.9 0.24 11.5 6.9 15.7 4 3 11 15 15 15 9 Coagulation Factor Xa inhibitory site EGF_3 PF12947.2 KFM08455.1 - 4.5e-09 36.1 214.6 0.0016 18.3 1.9 16.3 9 5 6 15 15 15 10 EGF domain cEGF PF12662.2 KFM08455.1 - 7 6.3 199.2 0.048 13.3 2.6 18.2 15 7 0 15 15 15 0 Complement Clr-like EGF-like EMI PF07546.8 KFM08456.1 - 5.4e-16 58.8 5.0 5.4e-16 58.8 3.5 2.7 2 1 0 2 2 1 1 EMI domain EGF_CA PF07645.10 KFM08456.1 - 1.4e-10 40.9 6.3 1.4e-10 40.9 4.3 3.3 2 1 1 3 3 3 1 Calcium-binding EGF domain FXa_inhibition PF14670.1 KFM08456.1 - 1.4e-08 34.6 8.2 1.4e-08 34.6 5.7 3.2 3 1 0 3 3 3 1 Coagulation Factor Xa inhibitory site cEGF PF12662.2 KFM08456.1 - 2.6e-05 23.7 0.6 2.6e-05 23.7 0.4 3.8 4 1 0 4 4 4 2 Complement Clr-like EGF-like EGF PF00008.22 KFM08456.1 - 0.00027 20.8 25.9 0.0031 17.4 5.0 3.1 3 0 0 3 3 3 2 EGF-like domain EGF_2 PF07974.8 KFM08456.1 - 0.00079 19.5 9.4 0.00079 19.5 6.5 3.7 3 1 1 4 4 4 1 EGF-like domain EGF_3 PF12947.2 KFM08456.1 - 0.0023 17.8 3.6 0.0023 17.8 2.5 3.2 3 0 0 3 3 3 1 EGF domain hEGF PF12661.2 KFM08456.1 - 0.0066 16.4 3.0 0.0066 16.4 2.1 4.0 4 0 0 4 4 4 1 Human growth factor-like EGF Seryl_tRNA_N PF02403.17 KFM08456.1 - 0.064 13.2 0.1 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain SlyX PF04102.7 KFM08456.1 - 0.12 12.7 0.4 8.6 6.8 0.0 2.2 2 0 0 2 2 2 0 SlyX Uds1 PF15456.1 KFM08456.1 - 0.13 12.2 2.1 3.3 7.7 0.1 2.3 2 0 0 2 2 2 0 Up-regulated During Septation bZIP_2 PF07716.10 KFM08456.1 - 0.14 11.9 4.8 3.4 7.5 1.2 2.2 2 0 0 2 2 2 0 Basic region leucine zipper Pox_A_type_inc PF04508.7 KFM08456.1 - 0.26 11.1 6.1 3.2 7.7 0.9 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat TMF_DNA_bd PF12329.3 KFM08456.1 - 1.9 8.3 5.1 11 5.9 1.0 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Acyltransferase PF01553.16 KFM08457.1 - 5.3e-23 80.9 0.0 7.2e-23 80.4 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase PIP49_C PF12260.3 KFM08458.1 - 8.7e-62 207.8 0.5 8.7e-62 207.8 0.3 1.7 2 0 0 2 2 2 1 Protein-kinase domain of FAM69 PIP49_N PF14875.1 KFM08458.1 - 5.1e-57 191.9 0.0 9.8e-57 191.0 0.0 1.5 1 0 0 1 1 1 1 N-term cysteine-rich ER, FAM69 EF-hand_1 PF00036.27 KFM08458.1 - 0.00085 18.4 0.5 0.0083 15.3 0.0 2.7 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.1 KFM08458.1 - 0.0016 18.4 0.0 0.0045 17.1 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 KFM08458.1 - 0.0062 15.8 0.1 0.035 13.4 0.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KFM08458.1 - 0.0078 15.8 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair Ribosomal_S2 PF00318.15 KFM08459.1 - 1.4e-47 161.6 0.7 1.3e-24 86.6 0.0 2.0 1 1 1 2 2 2 2 Ribosomal protein S2 OLF PF02191.11 KFM08460.1 - 2.6e-98 328.2 6.4 4.3e-98 327.5 4.4 1.4 1 0 0 1 1 1 1 Olfactomedin-like domain Noelin-1 PF12308.3 KFM08460.1 - 1.3e-49 166.1 9.7 3.7e-49 164.7 4.0 2.7 3 0 0 3 3 3 1 Neurogenesis glycoprotein Nup54 PF13874.1 KFM08460.1 - 0.0024 17.5 8.7 0.0024 17.5 6.0 1.6 1 1 0 1 1 1 1 Nucleoporin complex subunit 54 Atg14 PF10186.4 KFM08460.1 - 0.0044 16.0 9.6 0.0067 15.4 6.6 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 KFM08460.1 - 0.0047 16.5 14.1 0.0087 15.6 9.8 1.4 1 0 0 1 1 1 1 IncA protein Pox_A_type_inc PF04508.7 KFM08460.1 - 0.0079 15.8 0.6 0.032 14.0 0.4 2.0 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat Baculo_PEP_C PF04513.7 KFM08460.1 - 0.0092 15.8 2.0 0.072 12.9 0.8 2.3 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Lipoprotein_7 PF01540.11 KFM08460.1 - 0.017 14.2 2.7 0.025 13.6 1.9 1.2 1 0 0 1 1 1 0 Adhesin lipoprotein Reo_sigmaC PF04582.7 KFM08460.1 - 0.032 13.4 0.2 0.046 12.8 0.1 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 KFM08460.1 - 0.058 13.6 3.4 4.8 7.5 2.4 3.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3926 PF13080.1 KFM08460.1 - 0.065 12.7 0.6 0.14 11.7 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3926) FH2 PF02181.18 KFM08460.1 - 0.11 11.3 8.8 0.4 9.5 0.1 2.2 1 1 1 2 2 2 0 Formin Homology 2 Domain DUF1664 PF07889.7 KFM08460.1 - 0.14 11.9 8.5 2.4 7.9 2.9 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Prismane PF03063.15 KFM08460.1 - 0.14 10.4 0.8 0.2 10.0 0.6 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Xpo1 PF08389.7 KFM08460.1 - 0.15 11.9 2.0 0.15 11.9 0.3 1.7 1 1 0 2 2 2 0 Exportin 1-like protein V_ATPase_I PF01496.14 KFM08460.1 - 0.22 9.3 6.4 0.35 8.6 4.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Syntaxin PF00804.20 KFM08460.1 - 0.23 11.6 10.3 0.26 11.4 3.7 2.8 1 1 1 2 2 2 0 Syntaxin Borrelia_REV PF03978.8 KFM08460.1 - 0.82 9.3 5.3 12 5.5 0.1 2.3 1 1 1 2 2 2 0 Borrelia burgdorferi REV protein Filo_VP35 PF02097.10 KFM08460.1 - 1.1 8.3 4.3 12 4.9 0.0 2.1 1 1 0 2 2 2 0 Filoviridae VP35 DUF310 PF03750.8 KFM08460.1 - 1.3 9.2 7.3 34 4.6 5.1 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF310) Laminin_II PF06009.7 KFM08460.1 - 1.3 8.8 8.5 0.61 9.8 2.3 2.4 1 1 1 2 2 2 0 Laminin Domain II DUF2203 PF09969.4 KFM08460.1 - 1.5 9.0 9.6 1.6 8.9 0.4 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) H-kinase_dim PF02895.9 KFM08460.1 - 1.8 8.9 8.0 58 4.1 5.5 2.6 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain MitMem_reg PF13012.1 KFM08460.1 - 1.8 8.6 9.7 1.3 9.0 4.4 2.5 2 1 0 2 2 1 0 Maintenance of mitochondrial structure and function Cytochrom_B562 PF07361.6 KFM08460.1 - 1.9 8.9 9.3 2.8 8.4 4.1 2.2 1 1 1 2 2 2 0 Cytochrome b562 DUF848 PF05852.6 KFM08460.1 - 1.9 8.2 12.2 5.9 6.7 3.2 2.3 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF1978 PF09321.5 KFM08460.1 - 2 7.8 12.6 0.46 9.8 2.2 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1978) Fib_alpha PF08702.5 KFM08460.1 - 2.5 8.2 10.9 1.5 8.9 3.9 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ADIP PF11559.3 KFM08460.1 - 4.8 7.0 14.8 5.4 6.9 6.1 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding CENP-Q PF13094.1 KFM08460.1 - 5.4 7.0 16.7 1.5e+02 2.3 11.5 2.2 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit BLOC1_2 PF10046.4 KFM08460.1 - 5.5 7.1 13.8 1.5 8.9 1.2 3.4 2 1 1 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Syntaxin_2 PF14523.1 KFM08460.1 - 5.8 7.0 11.8 73 3.4 6.8 2.5 1 1 1 2 2 2 0 Syntaxin-like protein Spectrin PF00435.16 KFM08460.1 - 6.7 7.0 12.6 12 6.2 0.4 2.5 1 1 1 2 2 2 0 Spectrin repeat DUF342 PF03961.8 KFM08460.1 - 7.9 4.7 11.6 1.8 6.8 4.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Collagen PF01391.13 KFM08461.1 - 8.1e-164 531.3 681.8 2.7e-09 36.4 24.9 22.2 4 2 13 17 17 17 14 Collagen triple helix repeat (20 copies) COLFI PF01410.13 KFM08461.1 - 7.1e-85 283.7 0.1 1e-84 283.2 0.1 1.2 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Laminin_G_2 PF02210.19 KFM08461.1 - 1.3e-11 44.6 0.0 2.4e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_3 PF13385.1 KFM08461.1 - 1.7e-05 25.0 0.0 3.2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_1 PF00054.18 KFM08461.1 - 0.038 13.9 0.0 0.075 13.0 0.0 1.4 1 0 0 1 1 1 0 Laminin G domain DUF781 PF05612.7 KFM08461.1 - 2.5 6.6 0.1 3.8 6.1 0.0 1.1 1 0 0 1 1 1 0 Mouse protein of unknown function (DUF781) Hormone_recep PF00104.25 KFM08462.1 - 4.1e-42 143.6 0.0 5.8e-42 143.1 0.0 1.1 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Nuc_recep-AF1 PF11825.3 KFM08462.1 - 3e-38 130.1 25.5 4.9e-38 129.4 17.7 1.4 1 0 0 1 1 1 1 Nuclear/hormone receptor activator site AF-1 zf-C4 PF00105.13 KFM08462.1 - 3.7e-32 110.3 16.2 6.2e-32 109.6 11.3 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) WD40 PF00400.27 KFM08463.1 - 1.1e-77 253.4 21.1 9.9e-13 47.4 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KFM08463.1 - 2.1e-13 49.3 6.8 0.00058 18.1 0.5 4.6 1 1 4 5 5 5 4 Nucleoporin Nup120/160 eIF2A PF08662.6 KFM08463.1 - 4e-12 46.2 1.1 8.1e-06 25.6 0.0 3.8 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Hira PF07569.6 KFM08463.1 - 0.00078 18.7 1.8 9.5 5.3 0.0 4.4 2 1 2 5 5 5 2 TUP1-like enhancer of split Nucleoporin_N PF08801.6 KFM08463.1 - 0.0029 16.4 8.1 0.049 12.3 1.1 4.2 1 1 1 3 3 3 1 Nup133 N terminal like DUF3312 PF11768.3 KFM08463.1 - 0.007 14.6 0.0 0.099 10.8 0.0 2.0 1 1 0 2 2 2 1 Protein of unknown function (DUF3312) CDtoxinA PF03498.9 KFM08463.1 - 0.032 13.5 1.2 0.21 10.9 0.1 2.5 1 1 0 2 2 2 0 Cytolethal distending toxin A/C family VID27 PF08553.5 KFM08463.1 - 0.074 11.2 0.0 0.12 10.6 0.0 1.3 1 0 0 1 1 1 0 VID27 cytoplasmic protein Bromodomain PF00439.20 KFM08464.1 - 6.4e-46 154.1 5.7 2.4e-24 85.0 0.3 2.5 2 0 0 2 2 2 2 Bromodomain Gon7 PF08738.5 KFM08464.1 - 0.002 18.0 5.9 0.002 18.0 4.1 3.3 4 0 0 4 4 4 1 Gon7 family MerR-DNA-bind PF09278.6 KFM08464.1 - 1.6 9.1 5.2 30 5.1 0.1 2.6 2 0 0 2 2 2 0 MerR, DNA binding DUF2359 PF10151.4 KFM08465.1 - 5.2e-06 25.2 0.0 7.2e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2359) ANF_receptor PF01094.23 KFM08466.1 - 2.5e-31 108.7 0.1 3.6e-31 108.2 0.1 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.17 KFM08466.1 - 2.6e-29 102.2 4.3 3.4e-29 101.8 3.0 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_6 PF13458.1 KFM08466.1 - 2.2e-09 37.1 0.0 3.3e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein PgaD PF13994.1 KFM08466.1 - 0.058 12.8 0.1 0.16 11.4 0.1 1.7 1 0 0 1 1 1 0 PgaD-like protein Cation_ATPase_C PF00689.16 KFM08466.1 - 0.18 11.3 6.8 0.065 12.7 0.8 2.1 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus Yae1_N PF09811.4 KFM08469.1 - 3e-12 45.8 32.8 5.5 6.5 22.7 3.5 1 1 0 1 1 1 1 Essential protein Yae1, N terminal Homeobox_KN PF05920.6 KFM08471.1 - 9.3e-15 54.0 0.3 2.3e-14 52.7 0.2 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KFM08471.1 - 2.5e-07 30.2 0.2 4.6e-07 29.3 0.2 1.4 1 0 0 1 1 1 1 Homeobox domain Dicty_REP PF05086.7 KFM08471.1 - 0.025 12.3 0.4 0.034 11.9 0.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Homez PF11569.3 KFM08471.1 - 0.053 12.5 0.0 0.13 11.3 0.0 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Astro_capsid PF03115.9 KFM08471.1 - 0.12 10.6 2.2 0.16 10.1 1.5 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Homeobox_KN PF05920.6 KFM08472.1 - 1e-14 53.9 0.2 2.2e-14 52.8 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KFM08472.1 - 6.9e-08 31.9 1.4 9e-08 31.6 0.4 1.6 2 0 0 2 2 2 1 Homeobox domain MRP-S32 PF10210.4 KFM08472.1 - 8e-05 22.8 0.5 0.00018 21.7 0.3 1.5 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S32 Homez PF11569.3 KFM08472.1 - 0.047 12.7 0.0 0.091 11.8 0.0 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez PLDc_3 PF13918.1 KFM08475.1 - 2.8e-38 131.1 0.0 4.2e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 PLD-like domain PLDc_2 PF13091.1 KFM08475.1 - 1.2e-25 89.7 0.0 1.5e-15 57.0 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KFM08475.1 - 1.2e-12 47.1 2.8 5.7e-09 35.4 0.5 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif zf-C2H2 PF00096.21 KFM08476.1 - 7.7e-14 51.1 7.2 4e-07 29.9 0.8 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM08476.1 - 9.9e-13 47.7 6.5 5.9e-08 32.6 0.0 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM08476.1 - 3.7e-10 39.3 6.2 1.6e-05 24.8 0.5 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM08476.1 - 1.6e-07 31.0 6.0 5.7e-05 22.8 0.8 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 KFM08476.1 - 3.8e-05 23.5 0.9 0.067 13.1 0.1 2.1 2 0 0 2 2 2 2 Zinc ribbon domain zf-C2H2_jaz PF12171.3 KFM08476.1 - 0.00063 19.8 2.0 0.26 11.4 0.1 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding DNA_RNApol_7kD PF03604.8 KFM08476.1 - 0.001 18.4 0.9 0.19 11.2 0.0 2.2 2 0 0 2 2 2 1 DNA directed RNA polymerase, 7 kDa subunit zf-LYAR PF08790.6 KFM08476.1 - 0.0021 17.6 1.8 0.14 11.8 0.1 2.2 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf-BED PF02892.10 KFM08476.1 - 0.0028 17.3 4.4 0.05 13.3 0.4 2.1 1 1 1 2 2 2 1 BED zinc finger TFIIS_C PF01096.13 KFM08476.1 - 0.0043 16.6 3.3 0.54 9.9 0.1 2.2 2 0 0 2 2 2 2 Transcription factor S-II (TFIIS) zf-C2HC_2 PF13913.1 KFM08476.1 - 0.012 15.2 0.7 0.41 10.3 0.0 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type CpXC PF14353.1 KFM08476.1 - 0.02 14.8 0.8 0.43 10.5 0.6 2.0 1 1 0 1 1 1 0 CpXC protein Zn_Tnp_IS1595 PF12760.2 KFM08476.1 - 0.021 14.6 2.3 0.033 14.0 1.6 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain HNH PF01844.18 KFM08476.1 - 0.027 14.3 0.5 3.4 7.6 0.0 2.2 2 0 0 2 2 2 0 HNH endonuclease SprT-like PF10263.4 KFM08476.1 - 0.027 14.1 1.4 0.06 13.0 0.8 1.6 1 1 0 1 1 1 0 SprT-like family C1_1 PF00130.17 KFM08476.1 - 0.027 14.1 1.8 0.043 13.5 0.8 1.7 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) LIM PF00412.17 KFM08476.1 - 0.046 13.7 1.9 0.25 11.4 1.3 1.9 1 1 0 1 1 1 0 LIM domain zf-C2H2_2 PF12756.2 KFM08476.1 - 0.049 13.7 2.0 3.9 7.6 0.2 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) YhfH PF14149.1 KFM08476.1 - 0.052 13.3 1.1 4.7 7.1 0.1 2.2 2 0 0 2 2 2 0 YhfH-like protein XPA_N PF01286.13 KFM08476.1 - 0.07 12.8 2.0 5.4 6.7 0.1 2.1 2 0 0 2 2 2 0 XPA protein N-terminal zf-DNL PF05180.7 KFM08476.1 - 0.1 12.3 1.0 0.12 12.0 0.7 1.3 1 0 0 1 1 1 0 DNL zinc finger Zn_ribbon_recom PF13408.1 KFM08476.1 - 0.11 12.7 2.4 2.4 8.4 0.0 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain zf-CSL PF05207.8 KFM08476.1 - 0.11 12.0 2.3 0.23 11.0 1.6 1.6 1 1 0 1 1 1 0 CSL zinc finger C1_4 PF07975.7 KFM08476.1 - 0.14 12.2 1.4 0.19 11.7 1.0 1.4 1 1 0 1 1 1 0 TFIIH C1-like domain DZR PF12773.2 KFM08476.1 - 0.14 12.0 1.4 0.31 10.8 1.0 1.6 1 1 0 1 1 1 0 Double zinc ribbon FYVE PF01363.16 KFM08476.1 - 0.15 11.9 4.9 0.37 10.7 3.4 1.6 1 1 0 1 1 1 0 FYVE zinc finger RRN7 PF11781.3 KFM08476.1 - 0.18 11.3 3.2 0.67 9.4 0.2 2.2 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Sgf11 PF08209.6 KFM08476.1 - 0.19 11.1 2.2 3.4 7.0 0.1 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) GATA PF00320.22 KFM08476.1 - 0.22 10.8 1.3 1.1 8.6 0.2 2.4 1 1 1 2 2 2 0 GATA zinc finger zinc_ribbon_2 PF13240.1 KFM08476.1 - 0.31 10.6 3.6 5 6.7 0.4 2.1 2 0 0 2 2 2 0 zinc-ribbon domain Ribosomal_L44 PF00935.14 KFM08476.1 - 0.31 11.0 2.1 13 5.9 0.1 2.1 1 1 1 2 2 2 0 Ribosomal protein L44 OrfB_Zn_ribbon PF07282.6 KFM08476.1 - 0.31 10.7 3.3 0.92 9.2 2.3 1.7 1 1 0 1 1 1 0 Putative transposase DNA-binding domain Desulfoferrod_N PF06397.7 KFM08476.1 - 0.34 10.3 3.7 2.9 7.3 0.6 2.2 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain zinc_ribbon_5 PF13719.1 KFM08476.1 - 0.37 10.4 3.0 4 7.1 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KFM08476.1 - 0.39 10.4 2.7 4.6 7.0 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain Ogr_Delta PF04606.7 KFM08476.1 - 0.4 10.3 2.9 0.75 9.4 2.0 1.5 1 1 0 1 1 1 0 Ogr/Delta-like zinc finger Elf1 PF05129.8 KFM08476.1 - 0.47 10.1 2.0 1.9 8.2 0.1 1.8 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-MYND PF01753.13 KFM08476.1 - 0.76 9.6 3.8 3.1 7.7 2.6 2.1 1 1 0 1 1 1 0 MYND finger zf-ribbon_3 PF13248.1 KFM08476.1 - 0.78 9.0 3.7 11 5.3 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-AN1 PF01428.11 KFM08476.1 - 1.3 8.9 3.8 8.6 6.3 0.1 2.3 2 0 0 2 2 2 0 AN1-like Zinc finger zf-H2C2_5 PF13909.1 KFM08476.1 - 1.6 9.0 10.7 1 9.6 1.7 2.8 2 2 0 2 2 2 0 C2H2-type zinc-finger domain PAX PF00292.13 KFM08477.1 - 5.3e-71 236.1 0.2 8.2e-71 235.5 0.2 1.3 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.1 KFM08477.1 - 2.5e-07 30.1 0.1 6.9e-07 28.7 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 KFM08477.1 - 0.0024 18.0 0.0 0.0038 17.3 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 KFM08477.1 - 0.041 14.6 0.0 0.1 13.4 0.0 1.7 1 1 1 2 2 2 0 Homeodomain-like domain Mito_carr PF00153.22 KFM08478.1 - 2.5e-49 164.9 1.3 5.4e-16 58.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Mago_nashi PF02792.9 KFM08479.1 - 0.024 14.3 3.7 0.24 11.0 0.2 2.3 1 1 1 2 2 2 0 Mago nashi protein DUF3810 PF12725.2 KFM08479.1 - 7.5 5.3 11.7 4.6 6.0 3.6 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3810) DUF3510 PF12022.3 KFM08479.1 - 9.5 6.3 11.8 1.5 8.9 1.3 3.6 2 1 1 4 4 4 0 Domain of unknown function (DUF3510) Fork_head PF00250.13 KFM08480.1 - 1.6e-47 159.4 0.5 3.2e-47 158.4 0.4 1.5 1 0 0 1 1 1 1 Fork head domain Fork_head_N PF08430.7 KFM08480.1 - 1.9e-19 70.4 29.4 1.9e-19 70.4 20.4 3.0 2 1 0 2 2 2 1 Forkhead N-terminal region HNF_C PF09354.5 KFM08480.1 - 5.9e-17 62.5 2.7 5.9e-17 62.5 1.9 4.3 4 2 1 5 5 5 1 HNF3 C-terminal domain TPR_11 PF13414.1 KFM08481.1 - 1.8e-79 261.3 52.5 1.7e-13 50.0 2.3 10.0 5 3 5 10 10 10 10 TPR repeat TPR_1 PF00515.23 KFM08481.1 - 7.4e-59 193.1 58.7 3.6e-05 23.1 0.0 17.0 18 1 0 18 18 17 14 Tetratricopeptide repeat TPR_2 PF07719.12 KFM08481.1 - 1.3e-50 165.2 47.1 1.5e-06 27.6 0.0 17.5 17 2 0 17 17 17 12 Tetratricopeptide repeat TPR_16 PF13432.1 KFM08481.1 - 4.7e-36 122.6 0.3 6.7e-05 23.4 0.0 10.4 3 3 4 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.1 KFM08481.1 - 2.7e-33 111.2 31.9 1.2e-05 24.7 0.0 13.7 11 1 2 13 13 13 7 Tetratricopeptide repeat TPR_9 PF13371.1 KFM08481.1 - 7.8e-33 112.1 12.5 1.1e-06 28.3 0.0 9.0 4 2 6 10 10 10 8 Tetratricopeptide repeat TPR_17 PF13431.1 KFM08481.1 - 2.9e-32 108.1 31.6 0.00043 20.2 0.7 12.5 14 0 0 14 14 12 8 Tetratricopeptide repeat TPR_12 PF13424.1 KFM08481.1 - 6.9e-24 83.5 33.8 0.0001 22.1 0.0 10.8 1 1 12 13 13 13 11 Tetratricopeptide repeat TPR_14 PF13428.1 KFM08481.1 - 2e-21 74.5 1.6 0.49 11.1 0.0 12.2 5 3 9 14 14 14 4 Tetratricopeptide repeat TPR_19 PF14559.1 KFM08481.1 - 3.1e-21 75.4 9.4 4.9e-06 26.7 0.0 8.3 7 2 1 9 9 9 4 Tetratricopeptide repeat Apc3 PF12895.2 KFM08481.1 - 6.1e-15 55.1 35.7 0.00036 20.6 2.4 7.8 4 3 3 7 7 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KFM08481.1 - 1.7e-12 46.0 5.9 0.46 10.4 0.0 9.7 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFM08481.1 - 3e-12 46.1 27.3 1.6 9.3 0.0 12.5 14 0 0 14 14 14 4 Tetratricopeptide repeat TPR_15 PF13429.1 KFM08481.1 - 7.4e-06 25.2 2.2 1.2 8.1 0.0 5.4 2 1 3 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KFM08481.1 - 0.015 15.1 8.1 1.8 8.5 0.0 5.1 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat Apc5 PF12862.2 KFM08481.1 - 0.089 12.6 8.1 13 5.6 0.0 5.1 4 2 0 4 4 4 0 Anaphase-promoting complex subunit 5 CPG4 PF15481.1 KFM08481.1 - 0.23 11.8 3.5 0.22 11.8 0.5 2.5 2 0 0 2 2 1 0 Chondroitin proteoglycan 4 7tm_1 PF00001.16 KFM08482.1 - 6.1e-69 232.0 28.1 7.8e-69 231.6 19.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM08482.1 - 4.1e-14 52.3 23.8 5.1e-14 52.0 16.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 KFM08482.1 - 5.6e-09 35.5 14.7 5.6e-09 35.5 10.2 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.4 KFM08482.1 - 3.4e-06 26.3 23.0 6e-06 25.5 15.2 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx T2SM PF04612.7 KFM08482.1 - 0.019 14.7 0.8 0.019 14.7 0.5 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M DUF4131 PF13567.1 KFM08482.1 - 2 7.7 4.6 29 4.0 3.2 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) COX7C PF02935.11 KFM08482.1 - 2.7 7.8 6.1 0.46 10.3 0.2 2.5 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VIIc 60KD_IMP PF02096.15 KFM08482.1 - 4 7.0 12.7 13 5.4 8.8 1.9 1 1 0 1 1 1 0 60Kd inner membrane protein Ribonuclease_P PF00825.13 KFM08483.1 - 0.12 12.2 0.3 0.12 12.2 0.2 1.1 1 0 0 1 1 1 0 Ribonuclease P Sec23_trunk PF04811.10 KFM08484.1 - 2.1e-81 272.9 0.0 2.9e-81 272.4 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KFM08484.1 - 5.8e-35 118.8 0.1 1.1e-34 117.9 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KFM08484.1 - 3.2e-33 114.1 0.0 6.9e-33 113.0 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KFM08484.1 - 4.6e-15 54.8 6.4 8.6e-15 54.0 4.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KFM08484.1 - 2.3e-13 49.6 0.0 6.1e-13 48.2 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat APP_E2 PF12925.2 KFM08484.1 - 0.11 12.1 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein AphA_like PF14557.1 KFM08484.1 - 0.2 11.1 0.2 0.36 10.3 0.2 1.3 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator SIP1 PF04938.7 KFM08485.1 - 1.1e-91 306.4 0.7 1.2e-91 306.2 0.5 1.0 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) TRAPP PF04051.11 KFM08486.1 - 1.6e-46 157.5 0.2 1.8e-46 157.4 0.2 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component TRAPP PF04051.11 KFM08487.1 - 4.6e-31 107.4 0.1 4.9e-31 107.3 0.1 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Pinin_SDK_N PF04697.8 KFM08488.1 - 1.5e-50 170.7 8.8 1.5e-50 170.7 6.1 3.7 3 1 0 3 3 3 1 pinin/SDK conserved region Pinin_SDK_memA PF04696.8 KFM08488.1 - 2.3e-50 169.5 20.9 2.3e-50 169.5 14.5 4.7 3 2 1 4 4 4 1 pinin/SDK/memA/ protein conserved region SH3_2 PF07653.12 KFM08489.1 - 1.3e-08 34.1 0.0 2.8e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain NPIP PF06409.6 KFM08489.1 - 0.00086 18.1 7.8 0.00086 18.1 5.4 2.8 3 0 0 3 3 3 1 Nuclear pore complex interacting protein (NPIP) Reo_sigmaC PF04582.7 KFM08489.1 - 1.4 8.0 14.3 2.1 7.4 1.1 2.9 2 2 0 2 2 2 0 Reovirus sigma C capsid protein zf-H2C2_2 PF13465.1 KFM08491.1 - 2.2e-29 100.2 29.5 1.3e-07 31.5 0.2 6.4 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.21 KFM08491.1 - 3.3e-23 80.5 26.3 5e-05 23.3 0.1 5.4 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM08491.1 - 2e-15 55.9 24.6 0.0001 22.4 1.9 5.4 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KFM08491.1 - 1.5e-05 24.5 4.2 0.37 10.4 0.0 4.8 5 0 0 5 5 5 2 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 KFM08491.1 - 0.0024 17.9 10.3 0.49 10.6 0.0 5.0 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM08491.1 - 0.005 16.9 9.9 0.61 10.3 0.1 4.6 4 0 0 4 4 4 2 Zinc-finger of C2H2 type CHORD PF04968.7 KFM08491.1 - 0.12 12.6 12.4 1.7 8.9 0.0 4.7 2 1 3 5 5 5 0 CHORD DUF1528 PF07515.6 KFM08491.1 - 0.12 12.4 0.6 1 9.4 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1528) zf-C2H2_2 PF12756.2 KFM08491.1 - 0.5 10.5 9.9 0.25 11.4 0.5 3.6 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 KFM08491.1 - 8.7 6.4 18.2 0.37 10.7 0.3 5.1 5 0 0 5 5 5 0 C2H2-type zinc finger UPF0564 PF10595.4 KFM08492.1 - 1.4e-73 247.8 45.8 2e-73 247.3 31.8 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0564 IGR PF09597.5 KFM08492.1 - 0.037 13.9 1.7 0.16 11.9 1.2 2.1 1 0 0 1 1 1 0 IGR protein motif RPA_interact_M PF14767.1 KFM08492.1 - 3.3 8.5 10.1 3.4 8.4 0.1 3.6 3 0 0 3 3 3 0 Replication protein A interacting middle FAD_binding_3 PF01494.14 KFM08493.1 - 4.9e-18 65.3 0.2 6.7e-11 41.8 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain SE PF08491.5 KFM08493.1 - 0.00011 21.1 0.0 0.00024 20.0 0.0 1.5 2 0 0 2 2 2 1 Squalene epoxidase Trp_halogenase PF04820.9 KFM08493.1 - 0.0053 15.4 0.0 0.065 11.8 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase GDA1_CD39 PF01150.12 KFM08494.1 - 1.6e-77 260.8 0.0 1.2e-76 257.9 0.0 2.1 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Aldedh PF00171.17 KFM08495.1 - 2.5e-118 395.3 0.0 2.8e-118 395.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KFM08495.1 - 0.011 14.5 0.0 0.017 13.8 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Ret_tiss PF10044.4 KFM08496.1 - 7.7e-22 77.6 0.0 8.4e-22 77.5 0.0 1.0 1 0 0 1 1 1 1 Retinal tissue protein Homeobox PF00046.24 KFM08497.1 - 4.8e-23 80.5 1.5 6.2e-23 80.1 1.0 1.1 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFM08497.1 - 0.0017 18.0 0.0 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 Homeobox KN domain AMP-binding_C PF13193.1 KFM08498.1 - 6e-10 39.9 0.2 1e-09 39.2 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ABC_membrane_2 PF06472.10 KFM08499.1 - 1e-78 264.3 1.5 1.4e-78 263.8 1.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KFM08499.1 - 1.7e-17 63.9 0.0 3.1e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SbmA_BacA PF05992.7 KFM08499.1 - 0.00076 18.7 1.8 0.0014 17.9 1.3 1.5 1 1 0 1 1 1 1 SbmA/BacA-like family AAA_16 PF13191.1 KFM08499.1 - 0.0031 17.5 0.1 0.0073 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.1 KFM08499.1 - 0.0038 16.8 0.0 0.031 13.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KFM08499.1 - 0.017 15.0 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 KFM08499.1 - 0.027 14.9 0.2 0.064 13.7 0.1 1.6 1 0 0 1 1 1 0 Miro-like protein AAA_22 PF13401.1 KFM08499.1 - 0.031 14.4 0.4 0.21 11.7 0.2 2.4 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 KFM08499.1 - 0.08 12.1 0.3 0.14 11.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DEAD PF00270.24 KFM08499.1 - 0.098 12.1 0.2 1.1 8.7 0.1 2.2 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_19 PF13245.1 KFM08499.1 - 0.1 12.3 0.1 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_23 PF13476.1 KFM08499.1 - 0.11 12.7 0.2 0.21 11.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KFM08499.1 - 0.13 11.7 0.2 0.28 10.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.4 KFM08499.1 - 0.14 11.6 0.1 0.25 10.8 0.1 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.1 KFM08499.1 - 0.15 11.4 0.5 0.92 8.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 KFM08499.1 - 0.18 11.0 0.0 0.72 9.0 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein MobB PF03205.9 KFM08499.1 - 0.18 11.4 0.3 0.33 10.6 0.2 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B HTH_Tnp_1 PF01527.15 KFM08500.1 - 5.5e-09 35.8 7.9 0.0034 17.3 0.0 4.5 5 0 0 5 5 5 3 Transposase HTH_23 PF13384.1 KFM08500.1 - 1.5e-05 24.5 3.5 0.58 9.8 0.0 4.5 4 0 0 4 4 4 2 Homeodomain-like domain HTH_28 PF13518.1 KFM08500.1 - 2.7e-05 24.0 9.7 0.9 9.6 0.1 5.2 5 0 0 5 5 5 2 Helix-turn-helix domain DUF1492 PF07374.6 KFM08500.1 - 0.00012 22.0 2.8 1.3 9.1 0.0 4.2 4 0 0 4 4 4 2 Protein of unknown function (DUF1492) OTU PF02338.14 KFM08500.1 - 0.018 15.6 0.0 0.04 14.4 0.0 1.6 1 0 0 1 1 1 0 OTU-like cysteine protease HTH_Tnp_1_2 PF13022.1 KFM08500.1 - 0.031 14.0 0.2 6.1 6.6 0.0 3.3 3 0 0 3 3 3 0 Helix-turn-helix of insertion element transposase Creb_binding PF09030.5 KFM08500.1 - 0.12 12.6 1.9 0.18 11.9 0.0 2.3 2 0 0 2 2 2 0 Creb binding HTH_26 PF13443.1 KFM08500.1 - 0.2 11.9 0.2 14 5.9 0.0 3.7 5 0 0 5 5 5 0 Cro/C1-type HTH DNA-binding domain Dispanin PF04505.7 KFM08501.1 - 5e-23 80.4 0.0 8.1e-23 79.7 0.0 1.3 1 0 0 1 1 1 1 Interferon-induced transmembrane protein Fe-S_biosyn PF01521.15 KFM08502.1 - 3.4e-08 33.4 0.0 7.5e-08 32.3 0.0 1.5 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis E1_DerP2_DerF2 PF02221.10 KFM08503.1 - 7.4e-30 103.9 0.2 8.1e-30 103.8 0.2 1.0 1 0 0 1 1 1 1 ML domain HECT PF00632.20 KFM08504.1 - 4.1e-81 272.5 0.1 6.1e-81 272.0 0.1 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Filamin PF00630.14 KFM08504.1 - 4.2e-11 43.2 0.2 5.5e-07 30.0 0.0 3.6 3 1 0 3 3 3 2 Filamin/ABP280 repeat DUF4432 PF14486.1 KFM08504.1 - 0.16 10.5 0.0 0.26 9.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) Fcf1 PF04900.7 KFM08505.1 - 3.1e-41 139.5 1.6 4.9e-41 138.9 1.1 1.3 1 0 0 1 1 1 1 Fcf1 2-oxoacid_dh PF00198.18 KFM08506.1 - 6.7e-80 267.6 0.2 8.2e-80 267.3 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KFM08506.1 - 3.4e-21 74.6 0.6 5.8e-21 73.9 0.4 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 KFM08506.1 - 0.0019 17.8 0.0 0.0045 16.6 0.0 1.6 1 0 0 1 1 1 1 Biotin-lipoyl like GCV_H PF01597.14 KFM08506.1 - 0.028 14.1 0.8 0.066 12.8 0.6 1.7 1 1 0 1 1 1 0 Glycine cleavage H-protein HlyD_2 PF12700.2 KFM08506.1 - 0.041 13.0 0.1 4.5 6.3 0.0 2.8 2 1 1 3 3 3 0 HlyD family secretion protein HlyD PF00529.15 KFM08506.1 - 0.049 12.9 0.0 0.083 12.1 0.0 1.4 1 0 0 1 1 1 0 HlyD family secretion protein PAT1 PF09770.4 KFM08506.1 - 4.4 5.4 5.4 5.5 5.1 3.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pkinase PF00069.20 KFM08507.1 - 5.9e-20 71.4 0.0 6.7e-19 68.0 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM08507.1 - 2.1e-11 43.3 0.0 3.2e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase MIT PF04212.13 KFM08507.1 - 0.0029 17.4 0.4 0.0051 16.6 0.3 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Kinase-like PF14531.1 KFM08507.1 - 0.01 14.8 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like PDGF PF00341.12 KFM08508.1 - 9.9e-27 92.8 5.4 1.1e-26 92.6 3.7 1.0 1 0 0 1 1 1 1 PDGF/VEGF domain IF-2B PF01008.12 KFM08509.1 - 9.3e-82 274.1 0.1 1.1e-81 273.9 0.1 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Xpo1 PF08389.7 KFM08509.1 - 0.11 12.3 0.1 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Exportin 1-like protein MutL_C PF08676.6 KFM08510.1 - 9.1e-13 48.0 0.5 2.6e-12 46.5 0.4 1.8 1 1 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 KFM08510.1 - 3.1e-11 42.7 0.0 2.8e-05 23.5 0.0 2.5 2 0 0 2 2 2 2 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.21 KFM08510.1 - 7.4e-10 38.5 0.1 1.7e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KFM08510.1 - 1.1e-09 38.0 0.1 2.8e-09 36.7 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Acylphosphatase PF00708.13 KFM08511.1 - 1.6e-21 76.1 0.2 2e-21 75.9 0.1 1.0 1 0 0 1 1 1 1 Acylphosphatase zf-C2HC_2 PF13913.1 KFM08512.1 - 4.9e-18 64.2 5.6 3.2e-09 36.2 0.1 2.3 2 0 0 2 2 2 2 zinc-finger of a C2HC-type Sgf11 PF08209.6 KFM08512.1 - 0.0012 18.1 5.1 0.03 13.6 0.4 2.5 2 0 0 2 2 2 2 Sgf11 (transcriptional regulation protein) zf-H2C2_2 PF13465.1 KFM08512.1 - 0.0019 18.4 2.4 1.2 9.5 0.1 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-CHCC PF10276.4 KFM08512.1 - 0.0019 17.9 2.6 0.076 12.8 0.2 2.5 2 0 0 2 2 2 1 Zinc-finger domain zf-Di19 PF05605.7 KFM08512.1 - 0.013 15.6 3.3 2.6 8.2 0.4 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF4574 PF15141.1 KFM08512.1 - 0.019 14.6 0.1 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4574) FYVE PF01363.16 KFM08512.1 - 0.023 14.5 3.4 0.14 12.0 0.2 2.2 2 0 0 2 2 2 0 FYVE zinc finger zf-C2H2_4 PF13894.1 KFM08512.1 - 0.025 14.8 9.3 0.6 10.5 0.7 3.5 3 1 1 4 4 4 0 C2H2-type zinc finger Nairovirus_M PF07948.6 KFM08512.1 - 0.026 12.6 0.6 0.026 12.6 0.4 1.5 2 0 0 2 2 2 0 Nairovirus M polyprotein-like Prok-RING_4 PF14447.1 KFM08512.1 - 0.04 13.4 2.5 0.13 11.8 0.4 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C2H2 PF00096.21 KFM08512.1 - 0.04 14.2 7.4 1.9 8.9 1.2 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-RING_3 PF14369.1 KFM08512.1 - 0.055 13.4 1.8 0.26 11.3 0.1 2.3 2 0 0 2 2 2 0 zinc-finger HypA PF01155.14 KFM08512.1 - 0.54 9.9 2.2 3.4 7.3 0.1 2.3 2 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family NinG PF05766.7 KFM08512.1 - 0.86 9.3 6.8 0.19 11.4 1.4 1.9 2 0 0 2 2 2 0 Bacteriophage Lambda NinG protein zf-C4_ClpX PF06689.8 KFM08512.1 - 4.6 6.8 8.6 2.3 7.7 1.0 2.8 3 0 0 3 3 3 0 ClpX C4-type zinc finger Pkinase PF00069.20 KFM08513.1 - 2.9e-53 180.6 0.0 4.2e-53 180.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RCC1 PF00415.13 KFM08513.1 - 1.7e-47 159.3 22.7 1.5e-13 50.7 0.1 8.1 7 1 1 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KFM08513.1 - 2.8e-34 115.9 16.2 1.9e-07 30.4 0.2 7.7 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat Pkinase_Tyr PF07714.12 KFM08513.1 - 1.4e-33 116.1 0.0 2.2e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM08513.1 - 0.00073 18.5 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like EMP24_GP25L PF01105.19 KFM08514.1 - 1e-37 129.6 0.0 1.2e-37 129.4 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Flag1_repress PF03614.8 KFM08514.1 - 0.047 13.2 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 Repressor of phase-1 flagellin bZIP_1 PF00170.16 KFM08515.1 - 1.2e-10 41.2 21.7 2e-10 40.4 15.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFM08515.1 - 5.7e-09 35.6 22.3 9.7e-09 34.9 15.4 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KFM08515.1 - 2.7e-07 30.7 15.2 4.2e-07 30.1 10.5 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor Macoilin PF09726.4 KFM08515.1 - 0.043 12.1 9.1 0.048 11.9 6.3 1.0 1 0 0 1 1 1 0 Transmembrane protein V_ATPase_I PF01496.14 KFM08515.1 - 0.55 8.0 4.5 0.61 7.8 3.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 KFM08515.1 - 1.1 8.8 9.5 1.7 8.2 6.6 1.4 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 KFM08515.1 - 1.2 8.0 8.8 1.4 7.8 6.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 KFM08515.1 - 1.2 7.9 12.2 1.8 7.4 8.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 UPF0542 PF15086.1 KFM08515.1 - 1.7 8.3 5.3 0.36 10.5 1.4 1.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 bZIP_1 PF00170.16 KFM08517.1 - 3.4e-11 42.9 9.1 4.5e-11 42.5 6.3 1.1 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFM08517.1 - 1.3e-09 37.7 12.8 1.5e-09 37.5 8.9 1.1 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KFM08517.1 - 3.4e-07 30.4 9.5 4.5e-07 30.0 6.6 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor Phlebovirus_NSM PF07246.6 KFM08517.1 - 0.00046 19.4 0.2 0.00054 19.2 0.1 1.2 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M SR-25 PF10500.4 KFM08517.1 - 0.0026 17.2 9.2 0.0032 16.9 6.3 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein HALZ PF02183.13 KFM08517.1 - 0.0064 16.1 2.6 0.0064 16.1 1.8 2.1 1 1 1 2 2 2 1 Homeobox associated leucine zipper IncA PF04156.9 KFM08517.1 - 0.0089 15.6 4.7 0.011 15.3 3.3 1.1 1 0 0 1 1 1 1 IncA protein BMP2K_C PF15282.1 KFM08517.1 - 0.028 14.5 5.1 0.029 14.5 3.6 1.1 1 0 0 1 1 1 0 BMP-2-inducible protein kinase C-terminus MAD PF05557.8 KFM08517.1 - 0.041 11.9 7.3 0.05 11.6 5.0 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein HAP1_N PF04849.8 KFM08517.1 - 0.044 12.7 3.7 0.051 12.5 2.6 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region AAA_11 PF13086.1 KFM08517.1 - 0.05 13.1 0.7 0.059 12.9 0.5 1.1 1 0 0 1 1 1 0 AAA domain DUF3450 PF11932.3 KFM08517.1 - 0.065 12.4 2.0 0.075 12.2 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF904 PF06005.7 KFM08517.1 - 0.068 13.4 2.2 0.068 13.4 1.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF904) TBPIP PF07106.8 KFM08517.1 - 0.092 12.2 2.1 0.13 11.8 1.4 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Seryl_tRNA_N PF02403.17 KFM08517.1 - 0.11 12.5 4.9 0.14 12.1 3.4 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain APG6 PF04111.7 KFM08517.1 - 0.14 11.2 2.7 0.16 11.0 1.9 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIVA PF05103.8 KFM08517.1 - 0.14 12.1 0.5 0.14 12.1 0.3 2.0 1 1 1 2 2 2 0 DivIVA protein CAF-1_p150 PF11600.3 KFM08517.1 - 0.34 10.2 9.3 0.4 10.0 6.4 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal TMPIT PF07851.8 KFM08517.1 - 0.44 9.5 1.6 0.55 9.2 1.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF2681 PF10883.3 KFM08517.1 - 0.76 10.0 4.8 1.6 8.9 3.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) DUF4011 PF13195.1 KFM08517.1 - 0.78 9.7 6.3 1 9.3 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) Mnd1 PF03962.10 KFM08517.1 - 0.96 9.0 4.8 1.2 8.7 3.4 1.1 1 0 0 1 1 1 0 Mnd1 family DivIC PF04977.10 KFM08517.1 - 2.2 7.8 6.6 5.7 6.4 4.6 1.7 1 1 0 1 1 1 0 Septum formation initiator BORG_CEP PF14957.1 KFM08517.1 - 2.9 8.8 6.9 3.8 8.4 4.8 1.2 1 0 0 1 1 1 0 Cdc42 effector MFS_1 PF07690.11 KFM08518.1 - 5.9e-32 110.7 49.5 4.5e-30 104.5 23.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily HPP PF04982.8 KFM08518.1 - 2.4 7.9 9.8 0.27 11.0 2.5 2.8 2 1 0 2 2 2 0 HPP family Erg28 PF03694.8 KFM08519.1 - 2.8e-09 36.9 5.8 3.6e-09 36.6 4.0 1.1 1 0 0 1 1 1 1 Erg28 like protein NADH5_C PF06455.6 KFM08519.1 - 0.1 11.9 2.5 0.14 11.5 1.6 1.4 1 1 0 1 1 1 0 NADH dehydrogenase subunit 5 C-terminus MrpF_PhaF PF04066.8 KFM08519.1 - 0.41 10.9 2.6 0.49 10.7 1.4 1.4 1 1 0 1 1 1 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) DUF2273 PF10031.4 KFM08519.1 - 2.6 7.7 5.3 0.21 11.2 0.4 1.6 2 0 0 2 2 2 0 Small integral membrane protein (DUF2273) TTL PF03133.10 KFM08520.1 - 6.2e-90 301.0 0.0 1.6e-89 299.7 0.0 1.6 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 KFM08520.1 - 6.2e-07 28.4 0.0 0.0016 17.2 0.0 2.7 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 KFM08520.1 - 0.0033 17.1 0.0 0.015 15.0 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain XkdW PF09636.5 KFM08520.1 - 0.01 15.6 4.0 1 9.2 0.1 3.2 3 0 0 3 3 3 0 XkdW protein RimK PF08443.6 KFM08520.1 - 0.019 14.4 0.0 0.065 12.7 0.0 1.9 1 0 0 1 1 1 0 RimK-like ATP-grasp domain TGFb_propeptide PF00688.13 KFM08521.1 - 4.4e-22 78.5 0.3 6.6e-22 77.9 0.2 1.2 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.15 KFM08521.1 - 7e-13 48.7 0.1 1.5e-12 47.6 0.1 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain IFT43 PF15305.1 KFM08522.1 - 1.3e-46 158.1 1.3 1.8e-46 157.7 0.9 1.2 1 0 0 1 1 1 1 Intraflagellar transport protein 43 Hormone_recep PF00104.25 KFM08524.1 - 7.8e-35 119.8 0.3 1.3e-34 119.1 0.2 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFM08524.1 - 5.7e-31 106.5 12.3 1.1e-30 105.6 8.5 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Vasohibin PF14822.1 KFM08525.1 - 2.2e-104 347.9 0.0 2.6e-104 347.7 0.0 1.0 1 0 0 1 1 1 1 Vasohibin zf-C3HC4 PF00097.20 KFM08527.1 - 0.00098 18.7 7.8 0.0021 17.6 5.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM08527.1 - 0.0047 16.9 7.4 0.0096 15.9 5.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM08527.1 - 0.055 13.1 7.8 0.11 12.1 5.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) NUDE_C PF04880.8 KFM08528.1 - 0.39 11.0 5.2 0.45 10.8 0.9 2.4 2 1 0 2 2 2 0 NUDE protein, C-terminal conserved region zf-DHHC PF01529.15 KFM08529.1 - 1.6e-17 63.4 9.6 1.6e-17 63.4 6.7 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase InaF-motif PF15018.1 KFM08529.1 - 0.14 11.5 2.9 0.34 10.4 2.0 1.6 1 0 0 1 1 1 0 TRP-interacting helix CoA_binding_3 PF13727.1 KFM08529.1 - 3.5 7.4 7.3 0.14 12.0 1.1 1.5 2 0 0 2 2 2 0 CoA-binding domain DUF221 PF02714.10 KFM08531.1 - 6.8e-91 304.4 25.0 6.8e-91 304.4 17.3 1.8 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KFM08531.1 - 8.9e-25 87.0 2.5 8.9e-25 87.0 1.8 5.3 5 2 0 5 5 5 2 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KFM08531.1 - 1.1e-11 45.0 0.2 2.2e-11 44.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF4131 PF13567.1 KFM08531.1 - 9.9 5.5 26.2 0.14 11.5 0.3 4.6 4 2 0 4 4 4 0 Domain of unknown function (DUF4131) PMT PF02366.13 KFM08532.1 - 1.1e-77 260.7 14.3 2.1e-77 259.7 9.9 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KFM08532.1 - 7.6e-26 90.8 0.2 1e-25 90.4 0.1 1.2 1 0 0 1 1 1 1 MIR domain GST_N_3 PF13417.1 KFM08533.1 - 8.8e-18 64.3 0.0 1.4e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KFM08533.1 - 4e-15 55.7 0.0 7.7e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFM08533.1 - 1.3e-14 53.9 0.0 2.3e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFM08533.1 - 1.9e-07 30.9 0.0 2.7e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFM08533.1 - 0.00022 21.0 0.0 0.00032 20.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFM08533.1 - 0.014 15.8 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GOLD_2 PF13897.1 KFM08534.1 - 6.5e-68 227.1 1.0 6.5e-68 227.1 0.7 1.6 2 0 0 2 2 2 1 Golgi-dynamics membrane-trafficking Golgin_A5 PF09787.4 KFM08536.1 - 1.4e-143 479.1 0.0 1.7e-143 478.8 0.0 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 5 Vps16_C PF04840.7 KFM08536.1 - 8.3e-11 41.4 3.6 1.4e-09 37.3 2.5 2.1 1 1 0 1 1 1 1 Vps16, C-terminal region Aha1_N PF09229.6 KFM08537.1 - 1.3e-42 144.8 1.0 2e-42 144.2 0.7 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 KFM08537.1 - 4.2e-23 81.7 1.4 5.2e-23 81.4 0.3 1.6 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein DUF1005 PF06219.7 KFM08537.1 - 0.041 12.5 0.1 1.1 7.9 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1005) AMOP PF03782.12 KFM08538.1 - 1.1e-42 145.5 1.9 1.1e-42 145.5 1.3 1.9 2 0 0 2 2 2 1 AMOP domain TSP_1 PF00090.14 KFM08538.1 - 4.5e-08 33.0 11.5 1.5e-07 31.3 8.0 2.0 1 0 0 1 1 1 1 Thrombospondin type 1 domain Daxx PF03344.10 KFM08538.1 - 0.085 11.3 8.4 0.13 10.7 5.8 1.3 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 KFM08538.1 - 1.7 7.3 10.7 2.5 6.7 7.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CobT PF06213.7 KFM08538.1 - 5.7 5.9 10.5 8.3 5.4 7.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Aminotran_1_2 PF00155.16 KFM08539.1 - 9.9e-60 202.3 0.0 1.2e-59 202.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KFM08539.1 - 0.0002 20.5 0.0 0.00033 19.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KFM08539.1 - 0.0034 16.1 0.0 0.0054 15.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V RRM_1 PF00076.17 KFM08540.1 - 1.9e-12 46.6 0.0 2.2e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM08540.1 - 1.1e-11 44.5 0.0 1.3e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM08540.1 - 2.9e-08 33.4 0.0 3.3e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3860 PF12976.2 KFM08540.1 - 0.063 13.0 0.0 0.094 12.5 0.0 1.4 1 1 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3860) RRM_3 PF08777.6 KFM08540.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.5 1 1 0 1 1 1 0 RNA binding motif SKIP_SNW PF02731.10 KFM08541.1 - 3e-66 221.7 7.9 3e-66 221.7 5.5 2.5 2 0 0 2 2 2 1 SKIP/SNW domain ABC1 PF03109.11 KFM08542.1 - 9e-40 135.3 0.1 1.5e-39 134.5 0.0 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 KFM08542.1 - 0.00034 20.4 0.2 0.12 12.0 0.1 2.6 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 KFM08542.1 - 0.0013 17.9 0.0 0.0056 15.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain DUF3446 PF11928.3 KFM08543.1 - 9.3 6.5 9.9 11 6.3 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) Laminin_G_2 PF02210.19 KFM08544.1 - 6.8e-16 58.4 0.1 1.1e-15 57.8 0.1 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.18 KFM08544.1 - 1.1e-05 25.4 0.2 1.8e-05 24.7 0.1 1.7 1 1 0 1 1 1 1 Laminin G domain Laminin_G_3 PF13385.1 KFM08544.1 - 0.031 14.5 0.2 0.055 13.6 0.1 1.4 1 1 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily DUF3439 PF11921.3 KFM08544.1 - 0.24 11.1 5.3 0.39 10.4 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Syndecan PF01034.15 KFM08545.1 - 1.2e-06 28.1 0.4 1.2e-06 28.1 0.3 2.0 1 1 1 2 2 2 1 Syndecan domain CD34_antigen PF06365.7 KFM08545.1 - 0.0058 16.3 0.1 0.0082 15.8 0.0 1.1 1 0 0 1 1 1 1 CD34/Podocalyxin family DUF202 PF02656.10 KFM08545.1 - 0.11 12.7 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF202) T4_deiodinase PF00837.12 KFM08546.1 - 1.7e-55 187.6 0.0 1.8e-55 187.5 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase tRNA_NucTransf2 PF09249.6 KFM08546.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 tRNA nucleotidyltransferase, second domain T4_deiodinase PF00837.12 KFM08547.1 - 1.7e-09 37.0 0.2 1.7e-09 37.0 0.1 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase Enkurin PF13864.1 KFM08548.1 - 0.031 14.4 6.9 0.039 14.1 4.8 1.1 1 0 0 1 1 1 0 Calmodulin-binding IL7 PF01415.11 KFM08548.1 - 0.037 13.6 0.3 0.043 13.4 0.2 1.1 1 0 0 1 1 1 0 Interleukin 7/9 family DUF1741 PF08427.5 KFM08548.1 - 0.043 13.2 0.7 0.045 13.2 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1741) ImpA-rel_N PF06812.7 KFM08548.1 - 0.061 13.0 0.1 0.088 12.5 0.1 1.2 1 0 0 1 1 1 0 ImpA-related N-terminal FBP PF07299.6 KFM08548.1 - 0.12 11.6 1.8 0.13 11.5 1.2 1.0 1 0 0 1 1 1 0 Fibronectin-binding protein (FBP) Filament PF00038.16 KFM08549.1 - 0.11 11.9 33.5 0.83 9.0 23.2 2.0 1 1 0 1 1 1 0 Intermediate filament protein Reo_sigmaC PF04582.7 KFM08549.1 - 0.25 10.4 2.8 0.4 9.8 1.6 1.4 1 1 0 1 1 1 0 Reovirus sigma C capsid protein IncA PF04156.9 KFM08549.1 - 0.51 9.8 44.6 1.2 8.6 17.4 2.2 1 1 1 2 2 2 0 IncA protein APG6 PF04111.7 KFM08549.1 - 0.78 8.7 38.9 1.9 7.4 10.3 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 GAS PF13851.1 KFM08549.1 - 1.2 8.2 40.9 0.35 10.0 12.6 2.4 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF720 PF05302.6 KFM08549.1 - 2.5 7.8 9.8 0.22 11.3 3.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF720) Golgin_A5 PF09787.4 KFM08549.1 - 4.8 5.5 31.4 21 3.4 21.4 1.8 1 1 1 2 2 2 0 Golgin subfamily A member 5 MbeD_MobD PF04899.7 KFM08549.1 - 6.4 6.7 13.9 1.4 8.8 5.6 2.6 1 1 2 3 3 3 0 MbeD/MobD like TraH PF06122.6 KFM08550.1 - 0.51 9.0 5.0 0.6 8.8 0.4 2.2 1 1 0 2 2 2 0 Conjugative relaxosome accessory transposon protein DUF1129 PF06570.6 KFM08550.1 - 3 7.0 5.8 4.7 6.4 0.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) Syntaxin-6_N PF09177.6 KFM08550.1 - 4.6 7.7 34.9 4.2 7.8 5.3 4.3 3 1 1 4 4 4 0 Syntaxin 6, N-terminal 7tm_1 PF00001.16 KFM08551.1 - 4.2e-40 137.5 20.3 6.1e-40 136.9 14.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 KFM08551.1 - 3.8e-05 22.9 14.2 3.9e-05 22.8 9.2 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx GnHR_trans PF12369.3 KFM08551.1 - 0.044 14.2 4.6 0.07 13.5 0.2 2.3 2 0 0 2 2 2 0 Gonadotropin hormone receptor transmembrane region TFIIA PF03153.8 KFM08552.1 - 2.2e-90 304.2 50.5 1.8e-87 294.6 35.0 2.6 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Zip PF02535.17 KFM08552.1 - 1.2 8.0 5.3 0.56 9.1 1.0 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter Senescence_reg PF04520.8 KFM08552.1 - 1.4 9.3 12.4 1.1 9.6 1.0 2.4 2 0 0 2 2 2 0 Senescence regulator SelP_N PF04592.9 KFM08552.1 - 1.5 8.1 12.5 0.036 13.4 4.0 1.7 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Pox_Ag35 PF03286.9 KFM08552.1 - 2.4 7.6 12.6 0.62 9.5 4.8 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF4557 PF15101.1 KFM08552.1 - 4.1 7.1 17.2 0.17 11.7 6.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Daxx PF03344.10 KFM08552.1 - 4.8 5.5 25.0 0.53 8.7 9.8 2.1 2 0 0 2 2 2 0 Daxx Family RXT2_N PF08595.6 KFM08552.1 - 6.7 6.4 10.6 1 9.1 2.8 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal LAT PF15234.1 KFM08552.1 - 8 5.8 13.7 0.56 9.6 2.0 2.3 2 0 0 2 2 2 0 Linker for activation of T-cells Stonin2_N PF12016.3 KFM08553.1 - 1.8e-110 369.3 34.2 2.6e-110 368.7 23.7 1.2 1 0 0 1 1 1 1 Stonin 2 Adap_comp_sub PF00928.16 KFM08553.1 - 9.1e-53 179.0 0.1 1.9e-52 177.9 0.1 1.5 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Sel1 PF08238.7 KFM08554.1 - 6e-68 223.7 38.3 5.2e-09 36.4 0.2 12.9 12 0 0 12 12 12 11 Sel1 repeat fn2 PF00040.14 KFM08554.1 - 4.1e-19 68.2 6.4 7.8e-19 67.4 4.4 1.5 1 0 0 1 1 1 1 Fibronectin type II domain RVT_1 PF00078.22 KFM08555.1 - 0.0045 16.3 0.0 0.0079 15.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Yae1_N PF09811.4 KFM08556.1 - 2.2e-07 30.3 29.0 0.077 12.5 16.8 3.2 2 1 0 2 2 2 1 Essential protein Yae1, N terminal LRR_8 PF13855.1 KFM08558.1 - 2e-32 110.7 23.9 4.7e-12 45.4 2.9 4.5 4 0 0 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 KFM08558.1 - 5.5e-25 86.5 27.4 2.7e-06 26.8 0.5 7.4 4 3 2 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM08558.1 - 4.8e-17 59.3 19.8 0.079 13.0 0.1 11.6 10 1 1 11 11 11 3 Leucine Rich Repeat LRR_5 PF13306.1 KFM08558.1 - 1.6e-09 37.5 0.1 7.5e-06 25.6 0.0 3.4 2 1 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_7 PF13504.1 KFM08558.1 - 7.8e-07 28.2 23.0 11 6.7 0.1 11.0 11 0 0 11 11 11 1 Leucine rich repeat fn3 PF00041.16 KFM08558.1 - 1.6e-05 24.9 0.1 4.2e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain LRR_9 PF14580.1 KFM08558.1 - 0.0001 21.9 7.3 0.18 11.3 0.1 3.3 2 1 1 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.1 KFM08558.1 - 0.00011 21.9 22.0 5.5 7.3 0.1 8.7 7 3 2 9 9 9 2 Leucine Rich repeat LRRNT PF01462.13 KFM08558.1 - 0.00014 21.2 2.1 0.00014 21.2 1.5 3.8 4 0 0 4 4 4 1 Leucine rich repeat N-terminal domain LRRCT PF01463.19 KFM08558.1 - 0.0013 18.8 0.1 0.0045 17.1 0.1 2.0 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain MLANA PF14991.1 KFM08558.1 - 0.076 13.0 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein melan-A Glyco_hydro_59 PF02057.10 KFM08560.1 - 0 1037.3 6.9 0 1037.1 4.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Laminin_G_3 PF13385.1 KFM08560.1 - 0.0017 18.6 6.8 0.0021 18.3 2.5 2.6 3 1 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily Ion_trans_2 PF07885.11 KFM08561.1 - 1.2e-38 130.6 22.0 1.8e-19 69.2 0.6 3.4 3 1 1 4 4 4 2 Ion channel OST3_OST6 PF04756.8 KFM08561.1 - 0.0017 17.9 2.7 0.98 8.9 0.0 2.5 2 0 0 2 2 2 2 OST3 / OST6 family 7tm_1 PF00001.16 KFM08561.1 - 0.0095 15.0 0.5 0.0095 15.0 0.3 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) DUF2390 PF09523.5 KFM08561.1 - 0.091 12.9 2.3 0.19 11.9 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2390) Pox_A14 PF05767.7 KFM08561.1 - 0.38 10.7 7.3 2.1 8.3 0.6 3.1 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 HSD3 PF15244.1 KFM08562.1 - 3.1e-33 115.6 2.9 4.5e-33 115.1 2.0 1.2 1 0 0 1 1 1 1 Hydroxy-steroid dehydrogenase CARD PF00619.16 KFM08562.1 - 0.021 14.6 0.1 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Caspase recruitment domain PUF PF00806.14 KFM08562.1 - 0.051 13.0 0.3 0.15 11.6 0.1 1.9 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat BING4CT PF08149.6 KFM08562.1 - 0.11 11.9 0.6 7.5 6.1 0.1 2.3 2 0 0 2 2 2 0 BING4CT (NUC141) domain DUF3940 PF13076.1 KFM08562.1 - 0.16 11.5 1.6 0.33 10.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3940) Y_phosphatase PF00102.22 KFM08563.1 - 1.1e-73 247.4 0.1 1.9e-73 246.7 0.1 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase FERM_M PF00373.13 KFM08563.1 - 5.1e-23 81.6 2.6 2e-22 79.6 1.8 2.1 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.5 KFM08563.1 - 8.5e-18 64.1 0.3 8.5e-18 64.1 0.2 2.5 3 0 0 3 3 3 1 FERM N-terminal domain FERM_C PF09380.5 KFM08563.1 - 1.4e-16 60.4 0.2 3e-16 59.4 0.1 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain DSPc PF00782.15 KFM08563.1 - 9.7e-06 25.1 0.0 2.3e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFM08563.1 - 0.0046 17.2 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family BUD22 PF09073.5 KFM08563.1 - 0.25 10.3 3.3 0.39 9.7 2.3 1.2 1 0 0 1 1 1 0 BUD22 zf-CCCH_2 PF14608.1 KFM08564.1 - 5e-16 58.0 56.9 6.5e-07 29.1 3.9 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type PWI PF01480.12 KFM08564.1 - 0.15 12.1 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 PWI domain TPR_2 PF07719.12 KFM08565.1 - 4.1e-24 82.5 12.2 0.00066 19.4 0.1 8.4 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_11 PF13414.1 KFM08565.1 - 1.4e-23 82.3 26.9 2.2e-08 33.6 0.6 5.4 3 2 3 6 6 6 6 TPR repeat TPR_1 PF00515.23 KFM08565.1 - 7.6e-22 75.9 16.7 0.00069 19.1 0.2 7.3 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 KFM08565.1 - 1.2e-20 73.1 16.3 3.6e-06 26.8 0.3 5.4 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.1 KFM08565.1 - 8.4e-16 56.4 9.7 0.0056 16.3 0.1 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 KFM08565.1 - 2e-15 55.8 5.3 0.031 14.8 0.0 7.5 3 3 6 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFM08565.1 - 6.8e-15 55.2 8.4 7.2e-07 29.7 0.1 5.4 2 1 4 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 KFM08565.1 - 6.2e-14 52.0 10.3 0.001 19.3 0.7 5.5 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.1 KFM08565.1 - 4.6e-13 47.8 10.2 0.023 14.4 0.1 7.0 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 KFM08565.1 - 7.8e-07 28.8 12.6 0.026 14.6 0.2 7.2 7 1 0 8 8 7 1 Tetratricopeptide repeat Apc3 PF12895.2 KFM08565.1 - 1.2e-05 25.3 14.9 0.0045 17.0 0.4 4.0 1 1 3 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KFM08565.1 - 1.6e-05 25.0 15.8 0.68 10.5 0.3 7.1 8 1 1 9 9 7 2 Tetratricopeptide repeat TPR_10 PF13374.1 KFM08565.1 - 5e-05 23.0 9.7 0.017 15.0 1.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.1 KFM08565.1 - 0.00046 19.3 4.6 0.00053 19.1 0.4 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFM08565.1 - 0.00076 19.2 3.7 2.8 7.8 0.0 4.8 2 2 3 5 5 5 1 Tetratricopeptide repeat Tyr-DNA_phospho PF06087.7 KFM08566.1 - 6.1e-131 437.0 0.0 7.4e-131 436.8 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 KFM08566.1 - 0.033 13.9 0.0 1 9.1 0.0 2.4 2 0 0 2 2 2 0 PLD-like domain CAF-1_p150 PF11600.3 KFM08566.1 - 4 6.7 15.1 6.3 6.1 10.5 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ion_trans_2 PF07885.11 KFM08567.1 - 2.9e-20 71.7 23.5 2.6e-15 55.8 5.8 2.3 2 0 0 2 2 2 2 Ion channel Presenilin PF01080.12 KFM08567.1 - 2e-05 23.5 2.9 3.1e-05 22.9 2.0 1.2 1 0 0 1 1 1 1 Presenilin Bap31 PF05529.7 KFM08567.1 - 0.036 13.5 0.9 4.2 6.7 0.0 2.6 2 1 1 3 3 3 0 B-cell receptor-associated protein 31-like AAA PF00004.24 KFM08568.1 - 2.5e-43 147.4 0.0 6.3e-43 146.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 KFM08568.1 - 2.8e-07 30.6 0.1 8.4e-07 29.0 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KFM08568.1 - 2.8e-07 30.7 0.1 0.00039 20.5 0.0 2.4 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.8 KFM08568.1 - 2.7e-05 23.2 0.0 4.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 KFM08568.1 - 3.1e-05 23.7 0.5 0.00029 20.5 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KFM08568.1 - 4.8e-05 22.5 0.0 9.3e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KFM08568.1 - 6.3e-05 23.0 0.0 0.00034 20.6 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KFM08568.1 - 0.00039 21.2 0.3 0.0025 18.6 0.1 2.4 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KFM08568.1 - 0.00056 19.3 0.1 0.0013 18.2 0.1 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 KFM08568.1 - 0.00082 18.8 0.6 0.11 11.9 0.1 2.4 1 1 1 2 2 2 1 AAA domain SKI PF01202.17 KFM08568.1 - 0.0014 18.5 0.0 1.7 8.4 0.0 2.7 2 1 0 2 2 2 2 Shikimate kinase AAA_19 PF13245.1 KFM08568.1 - 0.0014 18.3 0.2 0.0029 17.3 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 KFM08568.1 - 0.0018 18.2 0.0 0.004 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFM08568.1 - 0.0026 17.6 0.0 0.0051 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KFM08568.1 - 0.003 17.5 0.0 0.0068 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFM08568.1 - 0.0033 17.7 1.0 0.0066 16.7 0.1 2.2 2 1 0 2 2 1 1 AAA domain AAA_3 PF07726.6 KFM08568.1 - 0.0043 16.6 0.1 0.073 12.6 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 KFM08568.1 - 0.0045 16.6 0.2 0.03 13.9 0.1 2.3 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 KFM08568.1 - 0.005 15.9 0.1 0.21 10.6 0.0 2.5 2 1 0 3 3 2 1 KaiC RNA_helicase PF00910.17 KFM08568.1 - 0.0058 16.7 0.0 0.014 15.5 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_11 PF13086.1 KFM08568.1 - 0.0088 15.6 0.5 1 8.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 KFM08568.1 - 0.0097 15.5 0.1 0.22 11.1 0.0 2.6 2 1 0 3 3 2 1 NACHT domain PhoH PF02562.11 KFM08568.1 - 0.01 15.1 0.0 0.045 12.9 0.0 2.0 2 0 0 2 2 2 1 PhoH-like protein Zeta_toxin PF06414.7 KFM08568.1 - 0.012 14.7 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin TIP49 PF06068.8 KFM08568.1 - 0.012 14.3 0.0 0.022 13.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.16 KFM08568.1 - 0.013 14.7 0.0 0.025 13.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.17 KFM08568.1 - 0.028 13.2 0.0 0.065 12.0 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain DivIC PF04977.10 KFM08568.1 - 0.063 12.7 0.2 1.9 8.0 0.2 2.4 2 0 0 2 2 2 0 Septum formation initiator ABC_tran PF00005.22 KFM08568.1 - 0.081 13.2 0.0 0.34 11.2 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Sigma54_activ_2 PF14532.1 KFM08568.1 - 0.092 12.7 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 KFM08568.1 - 0.092 11.5 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.1 KFM08568.1 - 0.095 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 KFM08568.1 - 0.14 11.6 0.1 0.57 9.6 0.0 2.0 2 1 0 2 2 2 0 Sigma-54 interaction domain NRDE-2 PF08424.5 KFM08569.1 - 3.2e-109 364.7 5.9 1e-107 359.8 1.4 3.8 4 1 1 5 5 5 3 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 KFM08569.1 - 1.6e-08 34.4 0.7 1.5 9.6 0.0 6.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFM08569.1 - 0.0042 17.4 0.4 16 5.9 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFM08569.1 - 0.0068 17.0 0.9 9.3 7.0 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF1675 PF07897.6 KFM08569.1 - 0.057 13.2 6.6 0.11 12.3 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) TPR_17 PF13431.1 KFM08569.1 - 0.31 11.3 3.1 76 3.8 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 KFM08569.1 - 2.1 8.4 8.5 3 7.9 0.1 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat EF-hand_1 PF00036.27 KFM08570.1 - 1.7e-43 142.5 10.0 3.2e-10 38.5 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KFM08570.1 - 8.9e-39 131.4 3.9 1.3e-21 76.4 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KFM08570.1 - 5.9e-36 121.8 10.2 4.3e-17 61.4 0.3 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 KFM08570.1 - 1.4e-31 105.5 5.4 1.1e-09 37.3 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KFM08570.1 - 2.9e-28 95.9 5.4 6.2e-07 28.4 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 KFM08570.1 - 8.8e-15 54.3 0.1 2.1e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KFM08570.1 - 2.2e-10 40.2 0.4 4.2e-05 23.2 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KFM08570.1 - 1.2e-08 34.9 0.0 0.0012 18.8 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.5 KFM08570.1 - 6e-07 29.3 1.6 8.2e-06 25.7 0.2 2.4 2 0 0 2 2 2 1 Ca2+ insensitive EF hand UPF0154 PF03672.8 KFM08570.1 - 1.3e-06 27.9 0.0 0.18 11.4 0.0 3.2 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) DUF1103 PF06513.6 KFM08570.1 - 0.00058 19.3 1.4 0.00068 19.0 1.0 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) TerB PF05099.8 KFM08570.1 - 0.0011 18.7 0.5 0.21 11.3 0.0 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB Caleosin PF05042.8 KFM08570.1 - 0.0013 18.3 0.1 0.036 13.6 0.1 2.6 1 1 0 1 1 1 1 Caleosin related protein RNA_pol_Rpb4 PF03874.11 KFM08570.1 - 0.015 15.3 1.7 2 8.4 0.1 2.5 3 0 0 3 3 2 0 RNA polymerase Rpb4 DUF3349 PF11829.3 KFM08570.1 - 0.016 15.5 0.4 13 6.2 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) Poly_export PF02563.11 KFM08570.1 - 0.049 13.4 0.1 2.8 7.7 0.0 2.9 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein MotA_activ PF09114.5 KFM08570.1 - 0.071 12.8 0.2 13 5.5 0.0 2.4 2 0 0 2 2 2 0 Transcription factor MotA, activation domain LNS2 PF08235.8 KFM08570.1 - 0.079 12.5 0.1 0.46 10.0 0.0 1.9 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) Toprim_2 PF13155.1 KFM08570.1 - 0.083 13.2 0.9 15 6.0 0.0 2.5 1 1 1 2 2 2 0 Toprim-like Tenui_NCP PF04876.7 KFM08570.1 - 0.098 12.1 0.1 0.96 8.9 0.0 2.0 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein DUF1880 PF08976.6 KFM08570.1 - 0.12 12.4 0.0 2.3 8.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) CMD PF02627.15 KFM08570.1 - 0.19 11.5 1.0 4.9 7.0 0.0 2.8 2 2 2 4 4 3 0 Carboxymuconolactone decarboxylase family VCBS PF13517.1 KFM08570.1 - 2.8 8.3 6.3 60 4.1 0.6 2.7 1 1 1 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Pkinase PF00069.20 KFM08571.1 - 1.4e-139 463.5 0.4 8.1e-70 234.9 0.2 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFM08571.1 - 1.9e-67 227.0 0.1 1.1e-33 116.4 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KFM08571.1 - 5.7e-15 55.0 0.0 2.4e-06 26.7 0.0 3.3 3 1 0 3 3 3 2 Kinase-like APH PF01636.18 KFM08571.1 - 1.4e-13 51.1 3.0 9.5e-05 22.2 0.0 4.2 2 2 2 4 4 4 4 Phosphotransferase enzyme family Kdo PF06293.9 KFM08571.1 - 4.2e-13 48.8 0.2 2.3e-09 36.5 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.19 KFM08571.1 - 6.6e-09 36.1 1.9 9.3e-09 35.6 0.3 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain RIO1 PF01163.17 KFM08571.1 - 6.1e-07 28.9 1.6 6.4e-05 22.3 0.1 2.4 2 0 0 2 2 2 2 RIO1 family Choline_kinase PF01633.15 KFM08571.1 - 0.00087 18.9 1.4 0.02 14.4 0.0 2.9 3 0 0 3 3 3 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 KFM08571.1 - 0.0047 16.2 7.4 0.03 13.6 0.0 3.5 3 1 1 4 4 4 1 PhoP regulatory network protein YrbL DUF2087 PF09860.4 KFM08571.1 - 0.04 13.6 1.0 2.9 7.7 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2087) DUF4392 PF14336.1 KFM08572.1 - 3.8e-89 298.3 0.0 4.9e-89 297.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4392) DUF1445 PF07286.7 KFM08572.1 - 2.7e-61 205.4 0.1 4.5e-61 204.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) SMK-1 PF04802.10 KFM08573.1 - 1.5e-84 282.3 9.2 2.6e-81 271.7 5.3 3.1 3 0 0 3 3 3 2 Component of IIS longevity pathway SMK-1 WH1 PF00568.18 KFM08573.1 - 0.00034 20.3 0.0 0.00076 19.1 0.0 1.6 1 0 0 1 1 1 1 WH1 domain Ran_BP1 PF00638.13 KFM08573.1 - 0.0057 16.6 0.0 0.02 14.9 0.0 2.0 1 0 0 1 1 1 1 RanBP1 domain Collagen PF01391.13 KFM08573.1 - 0.024 14.1 1.8 0.041 13.4 1.2 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) C2 PF00168.25 KFM08574.1 - 8.1e-12 44.8 0.0 3.2e-07 30.1 0.0 2.3 2 0 0 2 2 2 2 C2 domain EGF_CA PF07645.10 KFM08575.1 - 4.4e-46 154.6 89.6 2.1e-11 43.5 5.8 7.4 8 0 0 8 8 8 6 Calcium-binding EGF domain cEGF PF12662.2 KFM08575.1 - 2e-32 110.4 54.7 6.9e-11 41.5 1.8 7.6 8 0 0 8 8 8 6 Complement Clr-like EGF-like FXa_inhibition PF14670.1 KFM08575.1 - 7.1e-26 90.0 93.2 2.2e-08 34.0 6.5 8.8 8 1 0 8 8 8 5 Coagulation Factor Xa inhibitory site EGF_3 PF12947.2 KFM08575.1 - 6e-12 45.3 68.9 4.6e-06 26.4 3.6 7.8 7 1 1 8 8 8 5 EGF domain EGF PF00008.22 KFM08575.1 - 3.1e-07 30.2 90.1 7.8e-05 22.5 5.2 8.6 8 2 0 8 8 8 4 EGF-like domain Lebercilin PF15619.1 KFM08576.1 - 0.0035 16.7 13.1 0.0035 16.7 9.0 15.9 7 3 6 14 14 14 5 Ciliary protein causing Leber congenital amaurosis disease Josephin PF02099.12 KFM08577.1 - 9.6e-62 207.2 0.0 1.6e-61 206.5 0.0 1.3 1 0 0 1 1 1 1 Josephin UIM PF02809.15 KFM08577.1 - 1.1e-13 49.4 21.0 5.7e-05 22.3 0.9 4.0 3 0 0 3 3 3 3 Ubiquitin interaction motif NADH_oxidored PF08040.6 KFM08578.1 - 9.4e-35 118.0 0.0 1e-34 117.9 0.0 1.0 1 0 0 1 1 1 1 MNLL subunit CPSF100_C PF13299.1 KFM08579.1 - 3.7e-44 150.7 0.6 1.9e-43 148.4 0.0 2.1 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 KFM08579.1 - 2.4e-23 82.4 0.0 5.7e-23 81.2 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.7 KFM08579.1 - 2.7e-11 43.1 0.0 5.8e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 KFM08579.1 - 9.5e-08 31.9 0.0 1.9e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily VPS9 PF02204.13 KFM08580.1 - 1.3e-27 95.8 0.1 1.3e-27 95.8 0.0 1.8 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain RA PF00788.18 KFM08580.1 - 5.6e-07 29.9 0.5 1.6e-06 28.5 0.0 2.0 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain SH2 PF00017.19 KFM08580.1 - 0.045 13.5 0.0 0.18 11.5 0.0 2.2 1 0 0 1 1 1 0 SH2 domain AUX_IAA PF02309.11 KFM08580.1 - 0.42 10.3 6.1 1.1 8.9 4.2 1.7 1 0 0 1 1 1 0 AUX/IAA family Peptidase_C13 PF01650.13 KFM08581.1 - 1.9e-116 387.8 2.4 3.1e-116 387.1 1.7 1.3 1 0 0 1 1 1 1 Peptidase C13 family Golgin_A5 PF09787.4 KFM08582.1 - 1.9e-156 521.5 61.0 1.9e-156 521.5 42.3 3.4 1 1 2 3 3 3 1 Golgin subfamily A member 5 IncA PF04156.9 KFM08582.1 - 0.18 11.3 99.8 0.13 11.8 15.7 5.0 2 1 3 5 5 5 0 IncA protein Granin PF01271.12 KFM08583.1 - 3.8e-38 131.5 28.5 3.7e-22 78.7 15.9 3.0 1 1 2 3 3 3 2 Granin (chromogranin or secretogranin) Ins134_P3_kin PF05770.6 KFM08585.1 - 5.5e-116 386.8 0.2 7.2e-116 386.5 0.1 1.1 1 0 0 1 1 1 1 Inositol 1, 3, 4-trisphosphate 5/6-kinase Rep_fac_C PF08542.6 KFM08585.1 - 0.096 12.6 0.1 0.29 11.1 0.0 1.8 1 0 0 1 1 1 0 Replication factor C C-terminal domain DUF4583 PF15190.1 KFM08586.1 - 2.3e-74 247.1 2.6 2.6e-74 246.9 1.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4583) DUF4064 PF13273.1 KFM08586.1 - 0.0018 18.3 0.0 0.0025 17.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) AA_permease PF00324.16 KFM08586.1 - 0.038 12.3 0.2 0.052 11.8 0.1 1.2 1 0 0 1 1 1 0 Amino acid permease DUF4131 PF13567.1 KFM08586.1 - 0.061 12.7 7.0 0.028 13.8 1.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) GpcrRhopsn4 PF10192.4 KFM08586.1 - 0.12 11.5 0.1 0.12 11.5 0.1 2.1 2 1 1 3 3 3 0 Rhodopsin-like GPCR transmembrane domain DUF485 PF04341.7 KFM08586.1 - 2 8.1 6.7 1.5 8.5 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function, DUF485 PHD PF00628.24 KFM08587.1 - 0.0025 17.4 5.5 0.0025 17.4 3.8 3.3 3 1 0 3 3 3 1 PHD-finger zf-UBR PF02207.15 KFM08587.1 - 0.052 13.2 0.2 0.052 13.2 0.1 4.0 4 1 0 4 4 4 0 Putative zinc finger in N-recognin (UBR box) BTB PF00651.26 KFM08588.1 - 3.7e-25 88.0 0.5 6.3e-14 51.9 0.0 3.5 2 1 0 2 2 2 2 BTB/POZ domain BACK PF07707.10 KFM08588.1 - 1.7e-10 40.6 0.2 4.7e-10 39.2 0.1 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch UNC-79 PF14776.1 KFM08589.1 - 5.3e-11 41.6 0.1 7.1e-11 41.1 0.1 1.2 1 0 0 1 1 1 1 Cation-channel complex subunit UNC-79 UNC-79 PF14776.1 KFM08590.1 - 3e-204 679.3 8.3 5.3e-204 678.4 5.8 1.4 1 0 0 1 1 1 1 Cation-channel complex subunit UNC-79 Mito_fiss_reg PF05308.6 KFM08591.1 - 9.1 5.5 12.9 11 5.3 9.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Peptidase_C1 PF00112.18 KFM08592.1 - 4.7e-74 248.9 5.2 1.3e-73 247.5 3.6 1.6 1 1 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 KFM08592.1 - 3.7e-06 25.7 1.8 0.00016 20.3 0.6 2.1 2 0 0 2 2 2 2 Peptidase C1-like family FAM181 PF15238.1 KFM08593.1 - 3.2e-88 296.6 5.0 3.6e-88 296.4 3.4 1.0 1 0 0 1 1 1 1 FAM181 Ank_2 PF12796.2 KFM08594.1 - 1.2e-72 240.2 11.4 7.3e-20 71.1 0.2 5.3 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KFM08594.1 - 1.2e-62 204.7 17.1 8.5e-07 28.4 0.0 10.8 10 1 1 11 11 11 10 Ankyrin repeat Ank_4 PF13637.1 KFM08594.1 - 4.8e-49 163.9 11.9 8e-10 38.9 0.0 8.5 6 3 3 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM08594.1 - 2.2e-47 154.3 12.3 8.7e-05 22.3 0.0 11.1 11 0 0 11 11 11 9 Ankyrin repeat Ank_5 PF13857.1 KFM08594.1 - 5.1e-40 134.5 17.0 2.7e-11 43.3 0.3 10.1 3 2 9 12 12 12 10 Ankyrin repeats (many copies) SOCS_box PF07525.11 KFM08594.1 - 1.5e-13 50.3 5.4 1.1e-12 47.6 4.3 2.1 2 0 0 2 2 2 1 SOCS box DEAD PF00270.24 KFM08595.1 - 6.3e-30 103.8 0.3 6.6e-27 94.0 0.0 2.8 2 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KFM08595.1 - 2.3e-24 85.0 0.0 1.9e-22 78.8 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain HEAT PF02985.17 KFM08596.1 - 1.3e-10 40.4 5.7 0.064 13.3 0.0 7.2 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.1 KFM08596.1 - 6.6e-07 29.5 0.0 0.0052 17.0 0.0 4.4 3 2 1 4 4 4 3 HEAT repeats Vac14_Fab1_bd PF12755.2 KFM08596.1 - 0.00088 19.6 4.0 5.8 7.3 0.0 4.8 3 1 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KFM08596.1 - 0.024 15.1 2.7 1.9 9.0 0.0 4.6 4 1 1 5 5 5 0 HEAT-like repeat Serpin PF00079.15 KFM08597.1 - 2.2e-122 408.7 8.9 2.5e-122 408.6 6.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) FSH1 PF03959.8 KFM08597.1 - 0.048 13.1 0.1 0.1 12.0 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Serpin PF00079.15 KFM08598.1 - 3.2e-120 401.6 3.6 3.6e-120 401.4 2.5 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.15 KFM08599.1 - 1.4e-116 389.6 1.5 1.6e-116 389.5 1.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) JHBP PF06585.6 KFM08599.1 - 0.062 12.1 4.6 0.25 10.1 0.0 2.7 2 1 1 3 3 3 0 Haemolymph juvenile hormone binding protein (JHBP) Serpin PF00079.15 KFM08600.1 - 1.3e-114 383.2 1.7 1.5e-114 383.0 1.2 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.15 KFM08601.1 - 3.1e-115 385.2 1.5 3.5e-115 385.1 1.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.15 KFM08602.1 - 3.2e-111 372.0 0.5 3.6e-111 371.8 0.3 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) INCENP_N PF12178.3 KFM08602.1 - 0.011 15.2 0.2 2 8.0 0.0 2.4 2 0 0 2 2 2 0 Chromosome passenger complex (CPC) protein INCENP N terminal DUF4198 PF10670.4 KFM08602.1 - 0.038 14.0 0.0 0.061 13.3 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4198) Homeobox PF00046.24 KFM08603.1 - 4.1e-23 80.7 5.5 7.8e-23 79.8 3.8 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFM08603.1 - 0.0033 17.0 0.0 0.0076 15.9 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain Ribonuclease_3 PF00636.21 KFM08604.1 - 1.4e-67 225.2 0.2 2e-48 163.5 0.0 3.4 3 0 0 3 3 3 2 Ribonuclease III domain PAZ PF02170.17 KFM08604.1 - 1.4e-39 134.5 0.1 3.8e-39 133.0 0.1 1.8 1 0 0 1 1 1 1 PAZ domain Dicer_dimer PF03368.9 KFM08604.1 - 1.4e-30 104.9 0.0 4.8e-30 103.1 0.0 2.0 1 0 0 1 1 1 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.1 KFM08604.1 - 8.9e-21 74.1 0.0 1.1e-12 48.0 0.0 3.4 3 0 0 3 3 3 2 Ribonuclease-III-like Helicase_C PF00271.26 KFM08604.1 - 8e-18 64.0 0.0 2.1e-17 62.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFM08604.1 - 2.6e-12 46.5 0.0 5.1e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KFM08604.1 - 1.5e-10 41.2 0.0 4.9e-10 39.5 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit dsrm PF00035.20 KFM08604.1 - 0.00068 20.1 0.0 0.003 18.0 0.0 2.2 1 0 0 1 1 1 1 Double-stranded RNA binding motif Flavi_DEAD PF07652.9 KFM08604.1 - 0.19 11.4 0.0 1.4 8.7 0.0 2.2 2 0 0 2 2 2 0 Flavivirus DEAD domain CH PF00307.26 KFM08606.1 - 6.4e-32 109.8 0.1 4.4e-19 68.5 0.0 2.2 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFM08606.1 - 6.4e-07 28.9 0.0 0.0014 18.2 0.0 2.5 2 0 0 2 2 2 2 CAMSAP CH domain KASH PF10541.4 KFM08607.1 - 1.8e-23 82.1 8.5 3.2e-23 81.3 5.9 1.4 1 0 0 1 1 1 1 Nuclear envelope localisation domain Spectrin PF00435.16 KFM08607.1 - 1.5e-15 57.3 82.6 3.6e-06 27.1 3.1 8.9 6 1 3 9 9 9 7 Spectrin repeat Gamma-thionin PF00304.15 KFM08607.1 - 0.14 12.2 0.4 0.28 11.2 0.3 1.4 1 0 0 1 1 1 0 Gamma-thionin family Reo_sigmaC PF04582.7 KFM08607.1 - 2 7.4 16.5 0.37 9.9 0.2 4.1 4 1 1 5 5 5 0 Reovirus sigma C capsid protein Glutaredoxin PF00462.19 KFM08608.1 - 2.1e-05 24.3 0.1 0.00016 21.6 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin DUF2639 PF11121.3 KFM08608.1 - 0.033 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2639) 7tm_1 PF00001.16 KFM08610.1 - 7.4e-56 189.1 31.9 9e-56 188.8 22.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) ATG_C PF09333.6 KFM08611.1 - 1.4e-36 124.6 0.1 3.3e-36 123.3 0.1 1.7 1 0 0 1 1 1 1 ATG C terminal domain Chorein_N PF12624.2 KFM08611.1 - 5.9e-13 48.3 0.0 1.7e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG2_CAD PF13329.1 KFM08611.1 - 9.2e-07 28.5 1.7 2.9e-05 23.7 0.6 3.0 2 1 0 2 2 2 1 Autophagy-related protein 2 CAD motif DUF727 PF05303.7 KFM08612.1 - 1.7e-40 137.1 0.1 2.1e-40 136.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF727) Glyco_hydro_77 PF02446.12 KFM08612.1 - 0.022 13.3 0.0 0.025 13.1 0.0 1.1 1 0 0 1 1 1 0 4-alpha-glucanotransferase Dpy-30 PF05186.8 KFM08613.1 - 2.1e-19 68.7 1.0 2.5e-18 65.2 0.0 2.8 4 0 0 4 4 3 1 Dpy-30 motif ADK PF00406.17 KFM08613.1 - 3e-14 53.1 0.1 1.3e-07 31.6 0.1 3.4 2 1 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.1 KFM08613.1 - 4.1e-13 50.2 2.9 2.4e-12 47.7 2.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFM08613.1 - 7.1e-09 36.0 7.7 2.6e-08 34.2 0.4 3.1 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 KFM08613.1 - 2.5e-05 24.4 0.0 6.7e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFM08613.1 - 2.8e-05 24.1 0.2 0.00016 21.7 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 KFM08613.1 - 0.00024 21.0 0.8 0.00053 19.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 KFM08613.1 - 0.00056 20.0 0.0 0.0072 16.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KFM08613.1 - 0.00088 19.4 0.0 0.0037 17.4 0.0 2.1 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.1 KFM08613.1 - 0.0015 18.3 0.2 0.017 15.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KFM08613.1 - 0.0022 17.9 0.0 0.0022 17.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KFM08613.1 - 0.0028 17.3 0.1 0.01 15.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RIIa PF02197.12 KFM08613.1 - 0.0045 16.3 0.2 0.026 13.9 0.0 2.3 2 0 0 2 2 2 1 Regulatory subunit of type II PKA R-subunit AAA_25 PF13481.1 KFM08613.1 - 0.005 16.2 0.1 0.027 13.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 KFM08613.1 - 0.0051 16.5 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 NTPase NB-ARC PF00931.17 KFM08613.1 - 0.012 14.4 0.0 0.032 13.0 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain RuvB_N PF05496.7 KFM08613.1 - 0.019 13.9 0.0 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus ABC_tran PF00005.22 KFM08613.1 - 0.029 14.6 0.5 0.081 13.2 0.0 2.0 2 0 0 2 2 1 0 ABC transporter AAA_24 PF13479.1 KFM08613.1 - 0.032 13.8 1.1 0.1 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 KFM08613.1 - 0.033 14.1 0.0 0.13 12.2 0.0 2.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase GBP_C PF02841.9 KFM08613.1 - 0.039 13.1 12.0 0.41 9.7 4.5 2.3 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain Sigma54_activat PF00158.21 KFM08613.1 - 0.044 13.2 0.0 0.24 10.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Cytidylate_kin2 PF13189.1 KFM08613.1 - 0.052 13.4 3.6 0.17 11.8 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase-like family ArgK PF03308.11 KFM08613.1 - 0.07 11.8 0.0 0.18 10.5 0.0 1.6 1 0 0 1 1 1 0 ArgK protein SRP54_N PF02881.14 KFM08613.1 - 0.075 13.1 3.1 0.63 10.1 0.1 3.1 3 0 0 3 3 2 0 SRP54-type protein, helical bundle domain SKI PF01202.17 KFM08613.1 - 0.091 12.6 6.7 0.11 12.3 0.0 3.0 3 0 0 3 3 3 0 Shikimate kinase NACHT PF05729.7 KFM08613.1 - 0.1 12.2 0.0 0.29 10.7 0.0 1.8 1 0 0 1 1 1 0 NACHT domain ATP-synt_ab PF00006.20 KFM08613.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.5 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Guanylate_kin PF00625.16 KFM08613.1 - 0.7 9.2 5.2 1.2 8.5 0.0 3.0 3 0 0 3 3 2 0 Guanylate kinase AAA_23 PF13476.1 KFM08613.1 - 3.2 8.0 0.0 3.2 8.0 0.0 2.8 2 2 0 2 2 1 0 AAA domain DUF4131 PF13567.1 KFM08614.1 - 0.15 11.4 1.0 0.16 11.3 0.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) PAP_central PF04928.12 KFM08615.1 - 1.6e-108 361.3 0.0 3.4e-108 360.2 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 KFM08615.1 - 1.2e-36 125.5 2.0 3.2e-36 124.2 1.4 1.7 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 KFM08615.1 - 3.1e-09 37.0 0.1 7.4e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Pkinase PF00069.20 KFM08616.1 - 2.2e-16 59.7 0.1 7.6e-16 58.0 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM08616.1 - 1.4e-08 34.1 0.1 5.9e-08 32.0 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase EcKinase PF02958.15 KFM08616.1 - 0.0026 16.9 0.0 0.0044 16.1 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase APH PF01636.18 KFM08616.1 - 0.014 15.1 0.0 0.077 12.7 0.0 2.3 3 0 0 3 3 3 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KFM08616.1 - 0.049 12.4 0.1 0.069 11.9 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 KFM08616.1 - 0.1 11.5 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like zf-C2H2 PF00096.21 KFM08619.1 - 5.3e-24 83.0 55.4 1.8e-05 24.7 2.0 7.4 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM08619.1 - 4e-15 55.2 49.5 2.3e-07 30.7 0.9 8.2 8 0 0 8 8 8 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM08619.1 - 1.3e-11 43.9 51.9 0.01 16.1 0.3 7.6 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM08619.1 - 2.3e-10 39.9 49.0 1.2e-06 28.1 0.1 6.9 8 0 0 8 8 8 4 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KFM08619.1 - 0.0022 18.1 2.8 0.0022 18.1 1.9 5.2 6 0 0 6 6 6 2 C2H2-type zinc-finger domain zf-C2H2_7 PF15269.1 KFM08619.1 - 0.0074 16.1 13.0 0.29 11.0 0.4 3.7 3 0 0 3 3 3 2 Zinc-finger GAGA PF09237.6 KFM08619.1 - 0.057 13.0 7.9 1.4 8.5 0.4 3.0 2 1 0 2 2 2 0 GAGA factor DUF4329 PF14220.1 KFM08619.1 - 0.17 11.8 2.7 0.19 11.6 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4329) Daxx PF03344.10 KFM08619.1 - 0.32 9.4 14.3 0.49 8.8 9.9 1.2 1 0 0 1 1 1 0 Daxx Family zf-C2H2_jaz PF12171.3 KFM08619.1 - 1.7 8.9 44.6 0.57 10.4 1.4 6.0 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding Yae1_N PF09811.4 KFM08620.1 - 1.7e-09 37.0 33.1 0.15 11.5 19.0 3.5 2 1 0 2 2 2 1 Essential protein Yae1, N terminal Rubis-subs-bind PF09273.6 KFM08621.1 - 1.8e-35 121.6 0.1 4.2e-35 120.4 0.0 1.7 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.23 KFM08621.1 - 8.7e-11 42.3 0.0 1.2e-09 38.6 0.0 2.6 3 1 0 3 3 3 1 SET domain Cyclin_N PF00134.18 KFM08622.1 - 8.8e-17 60.8 5.7 2.2e-16 59.5 0.0 2.9 3 0 0 3 3 3 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFM08622.1 - 0.0073 16.2 0.1 0.0073 16.2 0.0 2.4 1 1 1 2 2 2 1 Cyclin, C-terminal domain Rrn6 PF10214.4 KFM08622.1 - 0.75 7.8 16.5 0.92 7.5 11.5 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Mitofilin PF09731.4 KFM08622.1 - 2.2 6.8 14.3 2.9 6.4 9.9 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein eIF-3_zeta PF05091.7 KFM08622.1 - 3.4 6.1 11.8 4.6 5.7 8.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Nucleo_P87 PF07267.6 KFM08622.1 - 5.1 5.6 9.1 6.8 5.2 6.3 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF4557 PF15101.1 KFM08622.1 - 5.7 6.7 15.9 9.4 6.0 11.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Hid1 PF12722.2 KFM08622.1 - 7.7 4.0 13.5 10 3.6 9.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GSDH PF07995.6 KFM08623.1 - 2.5e-40 138.5 0.0 3.1e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Folate_rec PF03024.9 KFM08623.1 - 6.8e-07 29.0 0.9 1.2e-06 28.2 0.6 1.3 1 0 0 1 1 1 1 Folate receptor family p450 PF00067.17 KFM08624.1 - 3.3e-90 302.8 0.4 4.1e-90 302.5 0.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 AAA_10 PF12846.2 KFM08624.1 - 0.03 13.7 0.5 0.056 12.8 0.1 1.6 1 1 1 2 2 2 0 AAA-like domain Sulfotransfer_2 PF03567.9 KFM08624.1 - 0.13 11.9 0.1 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Sulfotransferase family Lamprin PF06403.6 KFM08625.1 - 1.5e-05 24.7 17.7 0.0018 18.0 3.3 2.0 1 1 1 2 2 2 2 Lamprin PIP49_C PF12260.3 KFM08626.1 - 6.1e-06 25.7 0.0 1.1e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Nodulin_late PF07127.6 KFM08626.1 - 0.65 10.1 3.4 1.8 8.7 0.7 2.3 2 0 0 2 2 2 0 Late nodulin protein HELP PF03451.9 KFM08627.1 - 4.1e-38 128.7 0.3 7.5e-38 127.9 0.2 1.4 1 0 0 1 1 1 1 HELP motif WD40 PF00400.27 KFM08627.1 - 7.3e-27 92.2 39.2 7e-05 22.5 0.2 10.5 11 0 0 11 11 11 6 WD domain, G-beta repeat DPPIV_N PF00930.16 KFM08627.1 - 0.038 12.5 0.0 0.087 11.3 0.0 1.6 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Macoilin PF09726.4 KFM08627.1 - 0.4 8.9 1.8 0.59 8.3 1.2 1.2 1 0 0 1 1 1 0 Transmembrane protein SlyX PF04102.7 KFM08627.1 - 0.5 10.7 4.0 0.41 11.0 1.7 1.7 2 0 0 2 2 2 0 SlyX Matrilin_ccoil PF10393.4 KFM08627.1 - 1.1 8.6 3.1 2.4 7.5 0.4 2.2 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin FA_desaturase PF00487.19 KFM08629.1 - 7.4e-24 84.5 16.3 2.1e-23 83.1 11.3 1.6 1 1 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 KFM08629.1 - 5.3e-05 22.3 0.4 0.0002 20.4 0.1 2.2 2 0 0 2 2 2 1 Sphingolipid Delta4-desaturase (DES) zf-C2H2 PF00096.21 KFM08630.1 - 4.5e-19 67.5 22.9 2.5e-05 24.3 0.3 4.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM08630.1 - 1.3e-18 66.2 23.1 3e-08 33.5 0.1 4.8 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM08630.1 - 4.3e-14 51.7 17.6 0.00012 22.1 0.1 4.2 4 0 0 4 4 4 4 C2H2-type zinc finger Transpos_assoc PF13963.1 KFM08630.1 - 0.0022 17.9 6.4 0.029 14.3 0.1 2.8 3 0 0 3 3 3 2 Transposase-associated domain zf-RING_3 PF14369.1 KFM08630.1 - 0.0056 16.6 2.8 0.5 10.4 0.0 3.3 3 0 0 3 3 3 1 zinc-finger zf-C2H2_jaz PF12171.3 KFM08630.1 - 0.0057 16.7 13.5 2.1 8.5 0.5 4.2 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 KFM08630.1 - 0.0059 16.9 11.7 2 8.8 0.1 3.3 1 1 2 3 3 3 2 TRAF-type zinc finger CCAP PF11105.3 KFM08630.1 - 0.012 15.3 4.2 0.38 10.4 0.6 2.4 1 1 1 2 2 2 0 Arthropod cardioacceleratory peptide 2a Raffinose_syn PF05691.7 KFM08630.1 - 0.024 12.1 0.0 0.029 11.8 0.0 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 IBR PF01485.16 KFM08630.1 - 0.047 13.5 0.9 0.047 13.5 0.6 2.8 1 1 1 3 3 3 0 IBR domain CHORD PF04968.7 KFM08630.1 - 0.049 13.8 10.8 8 6.7 1.4 3.5 1 1 3 4 4 4 0 CHORD XPA_N PF01286.13 KFM08630.1 - 0.1 12.2 2.4 0.29 10.8 0.0 2.8 3 0 0 3 3 3 0 XPA protein N-terminal zf-CGNR PF11706.3 KFM08630.1 - 0.18 11.3 7.1 2.7 7.5 0.1 3.3 3 1 0 3 3 3 0 CGNR zinc finger zf-met PF12874.2 KFM08630.1 - 0.21 11.8 6.0 2.3 8.5 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFM08630.1 - 1.4 8.8 0.1 1.4 8.8 0.0 3.5 4 0 0 4 4 4 0 C2H2-type zinc finger Mito_carr PF00153.22 KFM08631.1 - 3.6e-67 222.1 1.6 5.7e-23 80.4 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.22 KFM08632.1 - 1.4e-72 239.4 1.1 4.6e-25 87.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_1b PF00579.20 KFM08633.1 - 7.8e-24 84.3 0.0 1.4e-23 83.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) WHEP-TRS PF00458.15 KFM08633.1 - 1.8e-21 75.5 0.1 3.9e-21 74.4 0.1 1.6 1 0 0 1 1 1 1 WHEP-TRS domain WD40 PF00400.27 KFM08634.1 - 2.4e-28 96.9 12.9 7.7e-08 31.9 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 KFM08634.1 - 8e-10 38.7 0.0 0.00024 20.8 0.0 3.3 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KFM08634.1 - 0.0095 14.1 0.2 0.056 11.5 0.0 2.0 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Pilt PF15453.1 KFM08635.1 - 4.7e-07 29.8 14.8 4.7e-07 29.8 10.2 2.9 2 1 0 2 2 2 1 Protein incorporated later into Tight Junctions IncA PF04156.9 KFM08635.1 - 0.054 13.0 14.8 0.066 12.8 9.3 1.9 1 1 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 KFM08635.1 - 0.06 11.1 4.1 0.099 10.4 2.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Homeobox PF00046.24 KFM08635.1 - 0.064 12.8 0.9 0.2 11.2 0.6 1.9 1 0 0 1 1 1 0 Homeobox domain DUF342 PF03961.8 KFM08635.1 - 0.4 9.0 6.7 0.66 8.3 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) ApoO PF09769.4 KFM08635.1 - 0.83 9.3 5.0 0.26 10.9 0.3 2.5 2 1 0 2 2 2 0 Apolipoprotein O DUF1664 PF07889.7 KFM08635.1 - 1.4 8.7 5.8 1 9.1 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) EGF PF00008.22 KFM08636.1 - 1.4e-29 101.6 88.6 4.9e-09 35.9 5.9 6.8 6 0 0 6 6 6 6 EGF-like domain hEGF PF12661.2 KFM08636.1 - 9.8e-14 50.4 46.5 0.001 18.9 0.6 7.3 6 0 0 6 6 6 6 Human growth factor-like EGF EGF_2 PF07974.8 KFM08636.1 - 6.3e-11 42.2 101.2 0.0059 16.7 6.3 6.4 6 0 0 6 6 6 6 EGF-like domain Laminin_EGF PF00053.19 KFM08636.1 - 0.24 11.3 70.3 0.086 12.7 5.6 6.5 3 2 3 6 6 6 0 Laminin EGF-like (Domains III and V) EGF_CA PF07645.10 KFM08636.1 - 0.28 11.2 79.3 0.057 13.4 6.2 6.7 4 1 2 6 6 6 0 Calcium-binding EGF domain FXa_inhibition PF14670.1 KFM08636.1 - 3.7 7.7 73.5 0.15 12.2 5.6 6.5 2 1 4 6 6 6 0 Coagulation Factor Xa inhibitory site T4_deiodinase PF00837.12 KFM08637.1 - 7.9e-42 142.8 0.0 9e-42 142.6 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase T4_deiodinase PF00837.12 KFM08638.1 - 1.4e-61 207.5 0.0 1.5e-61 207.3 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase B56 PF01603.15 KFM08639.1 - 4.6e-175 582.1 12.0 5.8e-175 581.7 8.3 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Dynein_heavy PF03028.10 KFM08640.1 - 7.8e-238 791.0 0.4 7.8e-238 791.0 0.3 2.3 2 0 0 2 2 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N1 PF08385.7 KFM08640.1 - 1.2e-195 651.3 10.0 1.2e-195 651.3 6.9 5.0 5 0 0 5 5 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 KFM08640.1 - 1.3e-125 419.1 13.4 1.3e-125 419.1 9.3 5.3 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 KFM08640.1 - 6.8e-82 274.4 0.0 3.3e-81 272.2 0.0 2.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 KFM08640.1 - 6.1e-44 150.0 0.0 4.2e-43 147.2 0.0 2.3 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 KFM08640.1 - 7.2e-44 149.3 0.3 5.4e-43 146.4 0.0 2.6 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 MT PF12777.2 KFM08640.1 - 2.4e-42 144.9 14.9 2.4e-42 144.9 10.4 2.2 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 KFM08640.1 - 4e-30 104.3 0.0 2.5e-12 46.7 0.0 5.8 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 KFM08640.1 - 3.2e-21 75.6 0.0 1.1e-20 73.8 0.0 2.0 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 KFM08640.1 - 3.5e-14 53.0 2.9 0.036 14.1 0.0 6.9 7 0 0 7 7 6 4 AAA domain AAA PF00004.24 KFM08640.1 - 1e-12 48.4 0.0 0.04 14.1 0.0 5.4 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KFM08640.1 - 1.6e-11 44.2 0.1 0.022 14.6 0.0 6.3 5 0 0 5 5 5 3 AAA domain AAA_16 PF13191.1 KFM08640.1 - 1.9e-10 40.9 5.9 0.014 15.4 0.0 6.4 7 0 0 7 7 6 3 AAA ATPase domain AAA_18 PF13238.1 KFM08640.1 - 9.5e-10 38.8 8.9 0.082 13.2 0.0 7.7 8 0 0 8 8 7 2 AAA domain AAA_17 PF13207.1 KFM08640.1 - 1.8e-09 38.4 0.0 0.056 14.2 0.0 6.3 4 0 0 4 4 4 1 AAA domain Mg_chelatase PF01078.16 KFM08640.1 - 5.8e-07 28.8 0.5 0.11 11.6 0.0 3.9 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KFM08640.1 - 5.2e-06 26.1 0.1 0.35 10.6 0.0 4.6 4 0 0 4 4 4 1 Part of AAA domain IstB_IS21 PF01695.12 KFM08640.1 - 6.6e-05 22.4 1.3 0.17 11.2 0.0 4.7 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_29 PF13555.1 KFM08640.1 - 0.00011 21.7 0.0 2 8.0 0.0 3.6 3 0 0 3 3 3 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KFM08640.1 - 0.00015 22.0 3.6 3.3 8.0 0.0 5.4 4 0 0 4 4 3 2 ABC transporter RNA_helicase PF00910.17 KFM08640.1 - 0.0012 19.0 0.0 12 6.1 0.0 5.4 6 0 0 6 6 5 0 RNA helicase AAA_10 PF12846.2 KFM08640.1 - 0.0019 17.7 1.7 4 6.7 0.0 4.9 4 0 0 4 4 4 1 AAA-like domain Phlebovirus_NSM PF07246.6 KFM08640.1 - 0.0022 17.1 2.1 0.0022 17.1 1.4 2.8 2 0 0 2 2 1 1 Phlebovirus nonstructural protein NS-M AAA_25 PF13481.1 KFM08640.1 - 0.0085 15.5 0.0 0.76 9.1 0.0 3.7 3 0 0 3 3 3 1 AAA domain HSP90 PF00183.13 KFM08642.1 - 1.7e-273 907.8 40.2 2.1e-273 907.5 27.8 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 KFM08642.1 - 2.6e-12 46.4 0.0 6.2e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KFM08642.1 - 6.7e-12 45.2 0.1 6.7e-12 45.2 0.1 2.5 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CDC45 PF02724.9 KFM08642.1 - 0.21 9.5 13.8 0.44 8.5 9.6 1.4 1 0 0 1 1 1 0 CDC45-like protein SF3a60_bindingd PF12108.3 KFM08642.1 - 0.85 9.2 5.4 6.1 6.4 0.1 2.8 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain WD40 PF00400.27 KFM08643.1 - 4.5e-16 58.0 12.0 9.7e-07 28.4 0.2 5.3 5 1 0 5 5 5 4 WD domain, G-beta repeat PD40 PF07676.7 KFM08643.1 - 0.0047 16.5 2.6 1.9 8.2 0.0 2.9 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat eIF2A PF08662.6 KFM08643.1 - 0.013 15.2 0.0 0.092 12.4 0.0 2.0 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A zf-C2H2 PF00096.21 KFM08644.1 - 0.042 14.1 0.2 0.098 13.0 0.1 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type ACDC PF14733.1 KFM08645.1 - 0.1 12.7 0.2 0.14 12.3 0.2 1.2 1 0 0 1 1 1 0 AP2-coincident C-terminal DUF3256 PF11644.3 KFM08646.1 - 0.02 14.3 1.1 0.023 14.2 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3256) AAA_8 PF12780.2 KFM08646.1 - 0.021 13.8 0.0 0.025 13.5 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 Med17 PF10156.4 KFM08646.1 - 0.54 8.4 4.1 2.4 6.3 2.9 1.9 1 1 0 1 1 1 0 Subunit 17 of Mediator complex Hyd_WA PF06462.7 KFM08647.1 - 8.4e-51 169.2 22.2 1.7e-08 33.9 0.5 9.0 9 0 0 9 9 9 6 Propeller WD40 PF00400.27 KFM08647.1 - 0.0011 18.7 0.0 0.008 16.0 0.0 2.6 1 0 0 1 1 1 1 WD domain, G-beta repeat Ank_2 PF12796.2 KFM08648.1 - 3.9e-13 49.5 0.2 1.3e-06 28.6 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFM08648.1 - 5.6e-08 33.1 0.3 7.1e-06 26.3 0.0 2.9 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM08648.1 - 7.8e-08 32.3 0.7 7.8e-07 29.1 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.25 KFM08648.1 - 9.1e-07 28.3 2.4 2e-06 27.2 0.1 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 KFM08648.1 - 0.013 15.7 0.9 0.32 11.3 0.1 3.2 3 0 0 3 3 3 0 Ankyrin repeat RVT_1 PF00078.22 KFM08649.1 - 0.015 14.6 0.0 0.029 13.7 0.0 1.5 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Myb_DNA-binding PF00249.26 KFM08650.1 - 1e-16 60.6 0.4 1.6e-08 34.4 0.0 2.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain ELM2 PF01448.19 KFM08650.1 - 0.0001 22.8 1.9 0.0002 21.9 0.0 2.5 2 1 0 2 2 2 1 ELM2 domain Myb_DNA-bind_6 PF13921.1 KFM08650.1 - 0.00047 20.1 3.2 0.44 10.6 0.1 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Tropomyosin_1 PF12718.2 KFM08650.1 - 0.075 12.8 13.4 0.2 11.4 9.3 1.7 1 0 0 1 1 1 0 Tropomyosin like DUF2422 PF10337.4 KFM08650.1 - 1.6 7.4 3.8 2.4 6.8 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) GOLD_2 PF13897.1 KFM08650.1 - 3.2 7.9 6.0 0.31 11.2 0.6 2.0 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking MATH PF00917.21 KFM08652.1 - 1.5e-28 99.3 0.0 1.3e-27 96.4 0.0 2.5 2 0 0 2 2 2 1 MATH domain zf-TRAF PF02176.13 KFM08652.1 - 5.2e-25 87.5 24.2 2.5e-16 59.8 5.4 4.4 2 2 2 4 4 3 2 TRAF-type zinc finger FliJ PF02050.11 KFM08652.1 - 0.0013 18.8 9.0 0.0024 17.9 6.3 1.4 1 0 0 1 1 1 1 Flagellar FliJ protein zf-C3HC4_2 PF13923.1 KFM08652.1 - 0.0037 17.2 14.4 0.0037 17.2 10.0 3.1 2 1 1 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM08652.1 - 0.0044 16.7 14.9 0.0044 16.7 10.3 3.2 3 2 0 3 3 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KFM08652.1 - 0.0053 16.3 15.8 0.0053 16.3 11.0 2.9 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) BLOC1_2 PF10046.4 KFM08652.1 - 0.014 15.4 7.1 0.42 10.7 3.9 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-C3HC4_4 PF15227.1 KFM08652.1 - 0.015 15.1 12.8 0.015 15.1 8.9 2.7 2 1 1 3 3 1 0 zinc finger of C3HC4-type, RING HrpB7 PF09486.5 KFM08652.1 - 0.021 14.7 3.3 0.052 13.4 0.2 2.3 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Tropomyosin_1 PF12718.2 KFM08652.1 - 0.081 12.7 13.9 0.2 11.5 9.6 1.7 1 1 0 1 1 1 0 Tropomyosin like zf-RING_6 PF14835.1 KFM08652.1 - 0.081 12.7 6.4 0.091 12.5 3.1 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein IncA PF04156.9 KFM08652.1 - 0.081 12.5 11.8 0.14 11.6 8.2 1.4 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 KFM08652.1 - 0.13 10.1 6.8 0.17 9.7 4.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Med9 PF07544.8 KFM08652.1 - 0.22 11.3 9.9 1 9.1 3.6 2.7 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 ATG16 PF08614.6 KFM08652.1 - 0.29 10.9 17.6 0.11 12.3 7.3 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) GAS PF13851.1 KFM08652.1 - 0.3 10.2 14.6 0.04 13.1 6.6 2.1 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding SNARE PF05739.14 KFM08652.1 - 1.1 9.0 7.6 0.37 10.5 2.5 2.1 2 0 0 2 2 2 0 SNARE domain Phage_GP20 PF06810.6 KFM08652.1 - 1.1 8.6 8.4 0.17 11.3 2.5 1.9 1 1 1 2 2 2 0 Phage minor structural protein GP20 ADIP PF11559.3 KFM08652.1 - 1.3 8.8 18.1 0.28 11.0 8.6 2.2 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Sina PF03145.11 KFM08652.1 - 1.7 8.2 37.1 0.057 13.0 2.3 4.0 2 1 3 5 5 4 0 Seven in absentia protein family Reo_sigmaC PF04582.7 KFM08652.1 - 1.7 7.7 5.1 1.7 7.7 1.2 1.7 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Amnionless PF14828.1 KFM08653.1 - 4.9e-111 371.3 0.0 5.5e-111 371.1 0.0 1.0 1 0 0 1 1 1 1 Amnionless VWC PF00093.13 KFM08653.1 - 5.5 7.1 9.2 14 5.9 6.4 1.7 1 0 0 1 1 1 0 von Willebrand factor type C domain CNH PF00780.17 KFM08654.1 - 3.1e-68 230.1 0.1 5.8e-68 229.2 0.1 1.5 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.20 KFM08654.1 - 8e-55 185.7 1.9 1.1e-54 185.2 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM08654.1 - 6.8e-29 100.7 0.0 6.8e-29 100.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase DMPK_coil PF08826.5 KFM08654.1 - 2.6e-26 91.2 11.3 2.6e-26 91.2 7.9 9.4 7 2 3 10 10 10 1 DMPK coiled coil domain like C1_1 PF00130.17 KFM08654.1 - 1.2e-09 37.7 5.4 2.5e-09 36.7 3.7 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 KFM08654.1 - 0.00026 21.4 2.6 0.00054 20.4 1.8 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain PBD PF00786.23 KFM08654.1 - 0.0019 18.5 0.7 0.0062 16.9 0.1 2.2 2 0 0 2 2 1 1 P21-Rho-binding domain Myosin_tail_1 PF01576.14 KFM08654.1 - 0.013 13.2 103.1 0.024 12.3 49.0 2.1 1 1 1 2 2 2 0 Myosin tail Reo_sigmaC PF04582.7 KFM08654.1 - 0.05 12.7 15.3 1.3 8.1 1.0 3.3 2 1 1 3 3 3 0 Reovirus sigma C capsid protein BBS2_N PF14781.1 KFM08654.1 - 0.14 11.7 0.0 1.2 8.8 0.0 2.4 1 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal APH PF01636.18 KFM08654.1 - 0.82 9.3 2.8 1 9.0 0.0 2.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Filament PF00038.16 KFM08654.1 - 1.3 8.4 87.5 0.14 11.6 12.3 4.8 1 1 2 4 4 4 0 Intermediate filament protein Baculo_PEP_C PF04513.7 KFM08654.1 - 4.8 7.0 17.0 2.4 7.9 0.3 4.3 2 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Yae1_N PF09811.4 KFM08655.1 - 9.2e-20 69.8 61.9 1.5e+04 -22.5 42.9 5.5 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Lbh PF15317.1 KFM08656.1 - 2.5e-24 85.3 0.7 2.7e-24 85.2 0.5 1.1 1 0 0 1 1 1 1 Cardiac transcription factor regulator, Developmental protein Sec6 PF06046.8 KFM08658.1 - 6.4e-66 222.6 2.0 8.2e-66 222.2 1.4 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec6 CTNNBL PF08216.6 KFM08658.1 - 0.049 13.2 0.2 0.16 11.5 0.1 1.9 1 0 0 1 1 1 0 Catenin-beta-like, Arm-motif containing nuclear DUF479 PF04336.7 KFM08658.1 - 0.2 11.7 1.8 0.91 9.6 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function, DUF479 Sec6 PF06046.8 KFM08659.1 - 1.2e-71 241.4 7.4 1.4e-71 241.2 5.1 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec6 DRIM PF07539.7 KFM08659.1 - 0.028 13.8 0.3 4.6 6.6 0.0 2.8 2 0 0 2 2 2 0 Down-regulated in metastasis SAC3 PF12209.3 KFM08659.1 - 3.5 7.8 6.4 2.4 8.3 0.1 3.4 3 0 0 3 3 3 0 Leucine permease transcriptional regulator helical domain eIF-5_eIF-2B PF01873.12 KFM08661.1 - 7.5e-47 158.0 0.6 4.4e-46 155.6 0.1 2.2 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.13 KFM08661.1 - 8.4e-25 86.5 5.7 8.4e-25 86.5 3.9 2.4 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon PGA2 PF07543.7 KFM08661.1 - 2.8 7.7 10.9 3.9 7.2 0.5 2.7 2 0 0 2 2 2 0 Protein trafficking PGA2 LIN37 PF15306.1 KFM08661.1 - 5.1 7.0 8.3 0.83 9.6 2.2 2.2 2 0 0 2 2 2 0 LIN37 Pkinase PF00069.20 KFM08662.1 - 3.7e-78 262.2 0.0 5.7e-78 261.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM08662.1 - 2.6e-45 154.5 0.0 5.1e-45 153.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 KFM08662.1 - 6.1e-19 67.1 0.0 1.2e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.1 KFM08662.1 - 1.3e-07 30.9 0.0 2.2e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KFM08662.1 - 7e-05 22.2 0.3 0.00015 21.1 0.2 1.5 1 0 0 1 1 1 1 RIO1 family UBA PF00627.26 KFM08662.1 - 0.00082 19.1 0.0 0.0018 18.0 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Kdo PF06293.9 KFM08662.1 - 0.0025 16.9 0.1 0.0044 16.1 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family UBA_2 PF08587.6 KFM08662.1 - 0.04 14.1 0.2 0.13 12.5 0.2 1.8 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) YrbL-PhoP_reg PF10707.4 KFM08662.1 - 0.073 12.3 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL ATP-gua_Ptrans PF00217.14 KFM08663.1 - 3.2e-92 308.2 0.0 4.4e-92 307.7 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 KFM08663.1 - 3e-34 116.9 0.0 4.5e-16 58.7 0.0 2.4 2 0 0 2 2 2 2 ATP:guanido phosphotransferase, N-terminal domain GCD14 PF08704.5 KFM08664.1 - 2.8e-111 370.9 0.0 3.3e-111 370.6 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 KFM08664.1 - 2.7e-07 30.3 0.0 4e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFM08664.1 - 9.2e-07 29.4 0.0 1.5e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFM08664.1 - 2.2e-05 24.4 0.0 3.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KFM08664.1 - 2.3e-05 24.0 0.0 3.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14_N PF14801.1 KFM08664.1 - 0.0038 16.7 0.6 0.0073 15.8 0.4 1.5 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_24 PF13578.1 KFM08664.1 - 0.0084 16.9 0.0 0.015 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 KFM08664.1 - 0.0094 14.9 0.0 0.013 14.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.1 KFM08664.1 - 0.012 15.9 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 KFM08664.1 - 0.012 16.0 0.0 0.023 15.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KFM08664.1 - 0.025 15.0 0.0 0.052 14.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 KFM08664.1 - 0.084 11.9 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase BAG PF02179.11 KFM08665.1 - 3.3e-67 222.5 23.5 8e-19 67.5 0.2 5.1 5 0 0 5 5 5 5 BAG domain DUF2682 PF10909.3 KFM08665.1 - 0.051 13.8 3.0 7.3 6.9 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2682) MIR PF02815.14 KFM08665.1 - 0.062 12.8 0.2 0.16 11.4 0.1 1.6 1 0 0 1 1 1 0 MIR domain RRF PF01765.14 KFM08665.1 - 0.57 9.6 10.0 0.79 9.1 1.3 3.4 3 0 0 3 3 3 0 Ribosome recycling factor DUF4061 PF13270.1 KFM08665.1 - 2.1 8.4 7.6 1.2 9.2 0.6 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4061) DUF2315 PF10231.4 KFM08666.1 - 1.7e-48 163.6 2.3 2e-48 163.4 1.6 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2315) TPR_12 PF13424.1 KFM08667.1 - 6.9e-74 243.8 27.7 2.9e-23 81.6 1.0 5.8 4 1 3 7 7 6 5 Tetratricopeptide repeat Rab5-bind PF09311.6 KFM08667.1 - 4e-68 228.8 15.4 4.6e-66 222.1 9.7 4.3 5 0 0 5 5 4 2 Rabaptin-like protein TPR_10 PF13374.1 KFM08667.1 - 1.4e-63 209.1 15.8 4.9e-16 58.0 0.0 6.7 7 0 0 7 7 6 6 Tetratricopeptide repeat TPR_7 PF13176.1 KFM08667.1 - 6.6e-31 103.6 18.7 6.6e-06 25.5 0.0 7.6 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.23 KFM08667.1 - 5.6e-29 98.5 31.3 1.1e-07 31.0 0.3 7.0 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.1 KFM08667.1 - 5.8e-25 86.7 19.6 2.4e-11 43.0 1.5 4.9 4 1 1 5 5 5 4 TPR repeat TPR_2 PF07719.12 KFM08667.1 - 1.1e-20 71.8 26.9 0.0004 20.0 1.8 6.7 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 KFM08667.1 - 5.2e-20 71.5 10.3 2.8e-06 27.8 0.1 4.8 4 1 1 5 5 4 4 Tetratricopeptide repeat TPR_14 PF13428.1 KFM08667.1 - 5.2e-15 54.5 9.7 0.19 12.4 0.3 7.0 3 1 4 7 7 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 KFM08667.1 - 7.1e-15 55.1 10.5 1.2e-05 25.5 0.2 4.8 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFM08667.1 - 1.8e-11 43.2 10.4 0.066 13.4 0.1 7.4 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFM08667.1 - 3.1e-11 42.2 19.7 0.073 12.8 0.1 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat Apc3 PF12895.2 KFM08667.1 - 1.1e-10 41.5 9.8 7e-06 26.0 2.2 3.7 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 KFM08667.1 - 2.5e-07 30.4 0.0 8.9 7.0 0.0 6.7 8 0 0 8 8 7 0 Tetratricopeptide repeat PPR PF01535.15 KFM08667.1 - 0.00043 20.0 3.0 0.16 11.9 0.0 4.5 7 0 0 7 7 3 1 PPR repeat DUF972 PF06156.8 KFM08667.1 - 0.0041 17.4 6.0 0.0041 17.4 4.2 3.6 3 0 0 3 3 3 1 Protein of unknown function (DUF972) PPR_3 PF13812.1 KFM08667.1 - 0.0067 16.6 1.2 3.3 8.2 0.0 4.5 5 0 0 5 5 5 1 Pentatricopeptide repeat domain TMF_DNA_bd PF12329.3 KFM08667.1 - 0.01 15.6 10.3 0.01 15.6 7.1 3.1 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SHNi-TPR PF10516.4 KFM08667.1 - 0.015 14.5 4.0 5.8 6.2 0.0 4.6 5 0 0 5 5 5 0 SHNi-TPR PPR_2 PF13041.1 KFM08667.1 - 0.068 13.1 0.3 1.2 9.1 0.0 3.2 3 0 0 3 3 3 0 PPR repeat family TPR_6 PF13174.1 KFM08667.1 - 0.26 11.8 0.2 0.26 11.8 0.1 6.7 7 0 0 7 7 6 0 Tetratricopeptide repeat DUF3366 PF11846.3 KFM08667.1 - 0.28 11.0 5.3 8.6 6.1 0.1 4.0 2 1 2 4 4 4 0 Domain of unknown function (DUF3366) COG2 PF06148.6 KFM08667.1 - 0.49 10.2 9.1 0.2 11.5 3.8 2.1 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TPR_3 PF07720.7 KFM08667.1 - 7.6 6.4 17.2 2.1 8.2 0.9 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat FYVE PF01363.16 KFM08668.1 - 1.9e-16 59.6 20.1 3.5e-16 58.8 13.9 1.5 1 0 0 1 1 1 1 FYVE zinc finger Mit_proteolip PF08039.6 KFM08669.1 - 1.5e-12 47.2 3.7 1.5e-12 47.2 2.6 1.0 1 0 0 1 1 1 1 Mitochondrial proteolipid RD3 PF14473.1 KFM08670.1 - 2.8e-49 165.9 3.1 3.8e-49 165.5 2.1 1.2 1 0 0 1 1 1 1 RD3 protein HA2 PF04408.18 KFM08671.1 - 1.6e-15 56.9 0.0 3.8e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) TUDOR PF00567.19 KFM08671.1 - 1.9e-15 56.8 0.0 5.8e-15 55.2 0.0 1.8 1 0 0 1 1 1 1 Tudor domain Helicase_C PF00271.26 KFM08671.1 - 3e-09 36.5 0.0 6.9e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Asparaginase PF00710.15 KFM08672.1 - 1.8e-111 372.0 0.0 3.7e-111 370.9 0.0 1.5 2 0 0 2 2 2 1 Asparaginase Ank_2 PF12796.2 KFM08672.1 - 9.9e-22 77.0 0.0 5.1e-19 68.3 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFM08672.1 - 2.6e-16 59.6 0.2 2.2e-08 34.4 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 KFM08672.1 - 3.3e-16 58.1 0.3 1.4e-09 37.2 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 KFM08672.1 - 5.6e-13 48.6 0.2 5.4e-09 36.0 0.0 3.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM08672.1 - 1.3e-12 46.6 0.4 1.2e-06 28.1 0.0 4.3 5 0 0 5 5 5 2 Ankyrin repeat DUF1282 PF06930.7 KFM08673.1 - 0.022 14.4 2.3 0.035 13.7 1.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) SHR3_chaperone PF08229.6 KFM08673.1 - 0.057 12.3 2.7 0.095 11.6 1.9 1.8 1 1 0 1 1 1 0 ER membrane protein SH3 Adenylsucc_synt PF00709.16 KFM08674.1 - 6.7e-148 492.8 0.0 7.5e-148 492.6 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Siva PF05458.7 KFM08675.1 - 2.2e-17 63.1 21.2 2.3e-17 63.1 14.7 1.0 1 0 0 1 1 1 1 Cd27 binding protein (Siva) APO_RNA-bind PF05634.6 KFM08675.1 - 0.9 8.6 6.6 0.98 8.5 4.6 1.1 1 0 0 1 1 1 0 APO RNA-binding DUF4637 PF15470.1 KFM08675.1 - 8.8 5.9 7.6 10 5.7 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Pkinase PF00069.20 KFM08676.1 - 1.1e-75 254.1 0.0 1.6e-75 253.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM08676.1 - 6.4e-36 123.7 0.0 9.7e-36 123.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 KFM08676.1 - 1.5e-08 34.7 0.4 4.3e-08 33.3 0.1 1.9 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.1 KFM08676.1 - 3.8e-08 32.6 0.0 1.7e-07 30.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.19 KFM08676.1 - 2.4e-07 31.1 3.0 6.2e-07 29.8 2.1 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Seadorna_VP7 PF07387.6 KFM08676.1 - 0.036 12.9 0.0 0.061 12.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PH_11 PF15413.1 KFM08676.1 - 0.045 13.9 0.9 0.31 11.3 0.6 2.4 1 1 0 1 1 1 0 Pleckstrin homology domain APH PF01636.18 KFM08676.1 - 0.07 12.8 0.0 0.18 11.5 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family CEP170_C PF15308.1 KFM08677.1 - 0 1072.6 59.4 0 1072.6 41.2 3.0 3 1 0 3 3 3 1 CEP170 C-terminus FHA PF00498.21 KFM08677.1 - 1.8e-17 63.1 0.1 5.7e-17 61.6 0.1 1.9 1 0 0 1 1 1 1 FHA domain PLDc_3 PF13918.1 KFM08678.1 - 1.3e-36 125.6 0.0 2.2e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 PLD-like domain PLDc_2 PF13091.1 KFM08678.1 - 1.1e-24 86.5 0.8 7.9e-14 51.4 0.1 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KFM08678.1 - 1.6e-13 49.9 3.6 1.8e-08 33.9 0.4 2.4 2 0 0 2 2 2 2 Phospholipase D Active site motif LRR_8 PF13855.1 KFM08679.1 - 7.6e-23 80.0 19.8 1.8e-12 46.7 0.7 4.7 2 2 3 5 5 5 3 Leucine rich repeat LRR_4 PF12799.2 KFM08679.1 - 3.3e-21 74.4 25.4 7.2e-08 31.8 0.2 5.1 3 1 4 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM08679.1 - 3.7e-14 50.5 22.3 0.16 12.1 0.0 9.4 10 0 0 10 10 10 5 Leucine Rich Repeat LRR_7 PF13504.1 KFM08679.1 - 1.7e-09 36.2 24.2 0.33 11.3 0.2 9.0 9 1 1 10 10 10 5 Leucine rich repeat LRR_9 PF14580.1 KFM08679.1 - 0.0028 17.2 6.2 0.0096 15.4 0.4 2.8 2 1 2 4 4 4 2 Leucine-rich repeat LRR_6 PF13516.1 KFM08679.1 - 0.0028 17.5 13.6 5.6 7.3 0.0 6.9 7 1 0 7 7 7 1 Leucine Rich repeat Filament PF00038.16 KFM08680.1 - 2.8e-30 105.8 35.2 2.8e-30 105.8 24.4 3.3 3 0 0 3 3 3 1 Intermediate filament protein Pkinase_Tyr PF07714.12 KFM08681.1 - 4.5e-97 324.1 0.0 6.6e-97 323.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM08681.1 - 1.1e-42 145.9 0.0 1.7e-42 145.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Furin-like PF00757.15 KFM08681.1 - 7e-33 113.3 34.2 7e-33 113.3 23.7 2.1 2 0 0 2 2 2 1 Furin-like cysteine rich region Recep_L_domain PF01030.19 KFM08681.1 - 1.3e-29 102.3 0.8 2.5e-29 101.4 0.5 1.5 1 0 0 1 1 1 1 Receptor L domain fn3 PF00041.16 KFM08681.1 - 5.6e-19 68.0 7.4 1.2e-06 28.5 0.0 4.7 4 1 0 4 4 4 4 Fibronectin type III domain Kinase-like PF14531.1 KFM08681.1 - 0.00018 20.5 0.0 0.0003 19.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Peptidase_C15 PF01470.12 KFM08683.1 - 6.3e-20 71.8 0.0 8e-20 71.5 0.0 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase DUF976 PF06162.7 KFM08683.1 - 0.00047 19.7 0.0 0.00061 19.3 0.0 1.1 1 0 0 1 1 1 1 Caenorhabditis elegans protein of unknown function (DUF976) Acetyltransf_7 PF13508.1 KFM08684.1 - 0.00043 20.3 0.0 0.001 19.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFM08684.1 - 0.0017 18.4 0.0 0.0085 16.2 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFM08684.1 - 0.046 13.7 0.0 0.09 12.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Actin PF00022.14 KFM08684.1 - 0.11 10.9 0.0 0.15 10.4 0.0 1.2 1 0 0 1 1 1 0 Actin Rad17 PF03215.10 KFM08685.1 - 1e-173 578.8 0.1 1.2e-173 578.4 0.0 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 KFM08685.1 - 4.6e-06 26.7 0.0 1.4e-05 25.1 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 KFM08685.1 - 7.2e-06 26.2 0.0 1.6e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KFM08685.1 - 1.2e-05 24.4 0.0 2.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KFM08685.1 - 6.4e-05 23.1 0.0 0.00015 21.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFM08685.1 - 0.00011 22.5 0.0 0.00039 20.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 KFM08685.1 - 0.00017 21.2 0.0 0.00033 20.3 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 KFM08685.1 - 0.00073 20.3 0.0 0.0017 19.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KFM08685.1 - 0.0033 17.3 0.0 0.008 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFM08685.1 - 0.0054 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 KFM08685.1 - 0.0058 16.6 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KFM08685.1 - 0.0069 16.5 0.0 0.025 14.7 0.0 2.1 2 0 0 2 2 1 1 RNA helicase UPF0079 PF02367.12 KFM08685.1 - 0.01 15.4 0.0 0.039 13.5 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 KFM08685.1 - 0.014 14.4 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 KFM08685.1 - 0.035 13.9 0.0 0.08 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DMA PF03474.9 KFM08685.1 - 0.038 13.8 0.1 0.14 12.0 0.0 2.0 2 0 0 2 2 1 0 DMRTA motif TIP49 PF06068.8 KFM08685.1 - 0.038 12.7 0.0 0.07 11.8 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus NACHT PF05729.7 KFM08685.1 - 0.1 12.2 0.0 0.59 9.7 0.0 2.2 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.22 KFM08685.1 - 0.11 12.7 0.2 0.34 11.2 0.0 1.9 1 1 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.16 KFM08685.1 - 0.13 11.4 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 KFM08685.1 - 0.13 11.8 1.7 0.31 10.5 0.0 2.2 2 1 1 3 3 3 0 AAA domain AAA_25 PF13481.1 KFM08685.1 - 0.15 11.4 0.0 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KFM08686.1 - 1.2e-25 90.3 0.4 3.4e-25 88.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KFM08686.1 - 1.2e-13 51.9 0.2 2.7e-13 50.7 0.1 1.5 1 1 1 2 2 2 1 AAA domain SKI PF01202.17 KFM08686.1 - 2.4e-05 24.2 1.8 0.005 16.7 0.0 2.8 2 1 1 3 3 3 1 Shikimate kinase AAA PF00004.24 KFM08686.1 - 0.00022 21.4 0.0 0.00047 20.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KFM08686.1 - 0.0013 18.7 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KFM08686.1 - 0.0043 17.1 0.0 0.017 15.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KFM08686.1 - 0.012 15.5 0.1 0.017 15.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain Cytidylate_kin2 PF13189.1 KFM08686.1 - 0.03 14.2 0.1 0.12 12.2 0.1 2.0 1 1 0 1 1 1 0 Cytidylate kinase-like family ADK PF00406.17 KFM08686.1 - 0.039 13.8 0.5 0.15 11.9 0.1 1.9 2 0 0 2 2 2 0 Adenylate kinase AAA_14 PF13173.1 KFM08686.1 - 0.089 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KFM08686.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 NTPase MerR-DNA-bind PF09278.6 KFM08687.1 - 0.053 13.9 6.3 1.1 9.7 0.0 3.3 3 0 0 3 3 3 0 MerR, DNA binding EHN PF06441.7 KFM08687.1 - 3.8 7.4 10.7 0.16 11.9 1.4 2.9 2 2 1 3 3 3 0 Epoxide hydrolase N terminus Cep57_CLD_2 PF14197.1 KFM08687.1 - 4.7 7.2 25.9 0.062 13.2 3.5 4.2 3 1 0 3 3 3 0 Centrosome localisation domain of PPC89 DUF3480 PF11979.3 KFM08688.1 - 4.6e-31 107.7 0.4 4.6e-31 107.7 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3480) FYVE PF01363.16 KFM08688.1 - 7.8e-20 70.5 15.3 2.2e-19 69.1 10.6 1.8 1 0 0 1 1 1 1 FYVE zinc finger SARA PF11409.3 KFM08688.1 - 0.006 16.4 4.3 0.017 15.0 3.0 1.8 1 0 0 1 1 1 1 Smad anchor for receptor activation (SARA) DUF3480 PF11979.3 KFM08689.1 - 1.1e-105 353.1 0.0 1.2e-105 353.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3480) DUF2181 PF10223.4 KFM08690.1 - 4.8e-86 288.0 0.1 5.4e-86 287.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2181) Ank_2 PF12796.2 KFM08691.1 - 1.8e-24 85.9 0.2 5e-19 68.4 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFM08691.1 - 8.1e-21 72.7 0.0 5.7e-08 32.1 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 KFM08691.1 - 2.6e-20 72.3 0.1 2.4e-06 27.9 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM08691.1 - 2.2e-15 55.2 0.1 2e-05 24.4 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 KFM08691.1 - 9e-14 51.1 0.1 3.3e-08 33.5 0.0 3.8 4 1 1 5 5 5 3 Ankyrin repeats (many copies) DHFR_1 PF00186.14 KFM08692.1 - 4e-27 94.7 0.0 4.4e-27 94.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrofolate reductase MutS_V PF00488.16 KFM08693.1 - 2.5e-87 292.1 0.0 4.6e-87 291.3 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KFM08693.1 - 1.8e-39 135.6 0.6 3.4e-39 134.7 0.4 1.5 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 KFM08693.1 - 3.2e-11 43.4 0.0 1e-10 41.8 0.0 1.9 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 KFM08693.1 - 2.2e-06 27.7 0.1 6.6e-06 26.2 0.1 1.8 1 0 0 1 1 1 1 MutS family domain IV AAA_22 PF13401.1 KFM08693.1 - 0.11 12.6 0.1 0.41 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain RVT_1 PF00078.22 KFM08694.1 - 0.0051 16.1 0.0 0.0081 15.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ATP-gua_Ptrans PF00217.14 KFM08696.1 - 2.7e-103 344.5 0.0 3.3e-103 344.2 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 KFM08696.1 - 2.3e-34 117.3 0.0 3.8e-34 116.6 0.0 1.3 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain FF PF01846.14 KFM08696.1 - 0.044 13.7 0.1 7.1 6.6 0.0 2.6 2 0 0 2 2 2 0 FF domain GD_AH_C PF04295.8 KFM08696.1 - 0.15 10.6 0.0 0.26 9.8 0.0 1.3 1 0 0 1 1 1 0 D-galactarate dehydratase / Altronate hydrolase, C terminus zf-CCHC PF00098.18 KFM08697.1 - 1.2e-15 56.5 26.9 3.2e-06 26.7 0.4 4.9 5 0 0 5 5 5 4 Zinc knuckle zf-CCHC_4 PF14392.1 KFM08697.1 - 1.1e-05 24.9 23.3 0.035 13.7 0.4 4.6 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.1 KFM08697.1 - 0.0006 19.2 15.4 0.23 10.9 0.4 4.3 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_5 PF14787.1 KFM08697.1 - 0.049 13.1 0.5 0.049 13.1 0.4 2.8 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger eIF3g PF12353.3 KFM08697.1 - 0.12 12.2 0.5 0.12 12.2 0.3 4.2 2 1 3 5 5 5 0 Eukaryotic translation initiation factor 3 subunit G Prim_Zn_Ribbon PF08273.7 KFM08697.1 - 2.3 8.3 12.2 3.9 7.6 0.1 3.7 4 0 0 4 4 4 0 Zinc-binding domain of primase-helicase DUF3720 PF12517.3 KFM08697.1 - 6.1 7.6 7.7 0.52 11.0 1.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3720) START PF01852.14 KFM08698.1 - 3.4e-19 68.9 0.1 4.1e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 START domain Polyketide_cyc2 PF10604.4 KFM08698.1 - 0.13 12.4 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport 4HBT PF03061.17 KFM08699.1 - 7.5e-21 74.0 1.1 3.7e-11 42.9 0.1 2.2 2 0 0 2 2 2 2 Thioesterase superfamily SSDP PF04503.8 KFM08700.1 - 4e-113 378.0 57.9 1.8e-110 369.2 40.2 2.0 1 1 0 1 1 1 1 Single-stranded DNA binding protein, SSDP Shisa PF13908.1 KFM08701.1 - 0.0073 16.5 0.1 0.008 16.3 0.0 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator WBP-1 PF11669.3 KFM08701.1 - 0.012 15.6 0.2 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 WW domain-binding protein 1 Herpes_gE PF02480.11 KFM08701.1 - 0.018 13.3 0.1 0.021 13.1 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DAG1 PF05454.6 KFM08701.1 - 0.044 12.9 0.1 0.048 12.8 0.0 1.0 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Trp_oprn_chp PF09534.5 KFM08701.1 - 0.078 12.5 0.0 0.078 12.5 0.0 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Rhabdo_glycop PF00974.13 KFM08701.1 - 0.084 11.0 0.1 0.084 11.0 0.1 1.0 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein EphA2_TM PF14575.1 KFM08701.1 - 0.12 12.7 0.1 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3049 PF11250.3 KFM08702.1 - 0.082 12.6 0.2 2.2 8.1 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3049) EF-hand_6 PF13405.1 KFM08703.1 - 6.4e-10 38.0 0.0 0.0085 15.9 0.0 4.4 5 1 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.27 KFM08703.1 - 1.3e-07 30.4 1.9 0.02 14.1 0.0 4.9 5 1 1 6 6 6 2 EF hand EF-hand_7 PF13499.1 KFM08703.1 - 2.1e-07 30.9 0.3 3.2e-06 27.1 0.2 2.8 1 1 0 1 1 1 1 EF-hand domain pair DUF2267 PF10025.4 KFM08703.1 - 0.01 15.9 0.4 0.055 13.5 0.1 2.1 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) EF-hand_8 PF13833.1 KFM08703.1 - 0.018 14.6 3.7 1 9.0 0.0 3.2 2 1 1 3 3 3 0 EF-hand domain pair DUF3734 PF12536.3 KFM08703.1 - 0.081 13.0 0.0 4 7.5 0.0 2.3 2 0 0 2 2 2 0 Patatin phospholipase 7tm_2 PF00002.19 KFM08704.1 - 1.1e-87 293.1 13.9 1.4e-87 292.8 9.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 KFM08704.1 - 9.3e-19 67.2 2.3 1.8e-18 66.3 1.6 1.5 1 0 0 1 1 1 1 Hormone receptor domain cwf18 PF08315.7 KFM08706.1 - 9.2e-35 119.9 9.7 1.1e-34 119.6 6.7 1.1 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor Arg_tRNA_synt_N PF03485.11 KFM08706.1 - 0.002 18.6 1.0 0.0027 18.2 0.7 1.2 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain DUF3639 PF12341.3 KFM08708.1 - 0.022 14.7 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3639) DUF3312 PF11768.3 KFM08708.1 - 0.047 11.9 0.0 0.12 10.5 0.0 1.6 1 1 0 2 2 2 0 Protein of unknown function (DUF3312) DUF1356 PF07092.7 KFM08709.1 - 3.1e-118 393.1 2.9 3.6e-118 392.9 2.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) MHC2-interact PF09307.5 KFM08709.1 - 0.039 13.7 0.2 0.2 11.4 0.0 2.0 2 0 0 2 2 2 0 CLIP, MHC2 interacting DnaJ_CXXCXGXG PF00684.14 KFM08709.1 - 0.13 12.3 0.8 0.48 10.4 0.6 1.8 1 1 0 1 1 1 0 DnaJ central domain EGF PF00008.22 KFM08710.1 - 1.3e-14 53.8 60.0 4.1e-05 23.4 5.4 4.5 4 0 0 4 4 4 4 EGF-like domain EGF_2 PF07974.8 KFM08710.1 - 4.4e-12 45.9 68.0 0.0013 18.8 8.0 4.2 4 0 0 4 4 4 4 EGF-like domain hEGF PF12661.2 KFM08710.1 - 1.1e-06 28.3 39.8 0.0004 20.2 1.1 6.3 5 1 0 5 5 5 3 Human growth factor-like EGF Laminin_EGF PF00053.19 KFM08710.1 - 1.3 9.0 50.0 2 8.4 7.2 4.2 1 1 3 4 4 4 0 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 KFM08711.1 - 5e-19 68.1 81.3 0.00048 20.2 8.0 5.2 5 0 0 5 5 5 5 EGF-like domain EGF PF00008.22 KFM08711.1 - 1.7e-16 59.8 69.7 0.00016 21.5 3.0 5.7 4 1 1 5 5 5 5 EGF-like domain hEGF PF12661.2 KFM08711.1 - 9.8e-16 56.6 51.5 0.00063 19.6 3.3 7.0 5 0 0 5 5 5 5 Human growth factor-like EGF Laminin_EGF PF00053.19 KFM08711.1 - 0.11 12.4 67.0 3.6 7.6 6.5 5.2 2 1 3 5 5 5 0 Laminin EGF-like (Domains III and V) EGF PF00008.22 KFM08712.1 - 0.00053 19.8 17.3 0.0012 18.8 4.2 4.2 4 0 0 4 4 4 2 EGF-like domain hEGF PF12661.2 KFM08712.1 - 0.018 15.1 9.2 0.027 14.5 0.1 3.9 3 0 0 3 3 3 0 Human growth factor-like EGF VWD PF00094.20 KFM08713.1 - 0.0069 16.5 0.4 0.014 15.6 0.3 1.5 1 0 0 1 1 1 1 von Willebrand factor type D domain Med1 PF10744.4 KFM08713.1 - 0.08 11.6 0.0 0.16 10.6 0.0 1.5 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription subunit 1 Gelsolin PF00626.17 KFM08714.1 - 4.4e-87 285.8 0.4 8.4e-19 67.0 0.0 6.3 6 0 0 6 6 6 6 Gelsolin repeat Arf PF00025.16 KFM08715.1 - 4.2e-67 224.7 0.0 4.9e-67 224.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KFM08715.1 - 6.9e-18 64.5 0.0 7.5e-18 64.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM08715.1 - 9.1e-15 55.2 0.1 1.3e-14 54.7 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 KFM08715.1 - 1.3e-12 47.2 0.1 1.3e-12 47.2 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KFM08715.1 - 6.1e-08 31.7 0.7 2.2e-06 26.6 0.1 2.2 1 1 1 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.22 KFM08715.1 - 7.6e-07 28.7 0.1 9.3e-06 25.2 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFM08715.1 - 1.5e-06 28.1 0.1 2e-06 27.7 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFM08715.1 - 8.1e-06 25.1 0.0 1e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 KFM08715.1 - 0.0025 17.4 0.0 0.0087 15.6 0.0 1.7 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein 6PF2K PF01591.13 KFM08715.1 - 0.017 14.2 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_28 PF13521.1 KFM08715.1 - 0.019 14.9 0.1 0.41 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain ACT PF01842.20 KFM08715.1 - 0.1 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 ACT domain ETS_PEA3_N PF04621.8 KFM08716.1 - 1.8e-146 487.7 21.3 2.4e-146 487.3 14.8 1.2 1 0 0 1 1 1 1 PEA3 subfamily ETS-domain transcription factor N terminal domain Ets PF00178.17 KFM08716.1 - 7.5e-38 128.5 0.2 1.2e-37 127.9 0.1 1.3 1 0 0 1 1 1 1 Ets-domain DAGK_acc PF00609.14 KFM08717.1 - 8.6e-45 152.7 0.1 2e-44 151.5 0.1 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAG_kinase_N PF14513.1 KFM08717.1 - 9.9e-45 152.1 0.0 5.5e-44 149.7 0.0 2.3 2 0 0 2 2 2 1 Diacylglycerol kinase N-terminus DAGK_cat PF00781.19 KFM08717.1 - 2.4e-30 104.6 0.0 4.3e-30 103.8 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.17 KFM08717.1 - 8.8e-21 73.3 35.0 1.9e-12 46.6 5.0 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) EF-hand_1 PF00036.27 KFM08717.1 - 1.4e-11 42.7 4.0 3.1e-05 22.9 0.1 3.2 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 KFM08717.1 - 5e-09 36.1 1.7 6.1e-09 35.8 0.2 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KFM08717.1 - 1e-08 34.3 0.3 0.00035 20.2 0.0 3.5 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.1 KFM08717.1 - 7.2e-08 31.4 0.1 0.017 14.4 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 KFM08717.1 - 2.1e-07 30.4 3.6 0.022 14.3 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFM08717.1 - 8.8e-05 22.4 0.2 0.0006 19.8 0.2 2.5 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Rhomboid PF01694.17 KFM08718.1 - 0.034 14.1 0.3 0.04 13.9 0.2 1.1 1 0 0 1 1 1 0 Rhomboid family FA_hydroxylase PF04116.8 KFM08719.1 - 1e-19 70.9 14.6 1e-19 70.9 10.2 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Homeobox PF00046.24 KFM08720.1 - 1.4e-13 50.2 1.5 1.6e-13 50.0 1.1 1.1 1 0 0 1 1 1 1 Homeobox domain Trep_dent_lipo PF09710.5 KFM08720.1 - 0.047 12.3 0.1 0.047 12.3 0.1 1.0 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) DUF2316 PF10078.4 KFM08720.1 - 0.096 12.6 0.1 0.11 12.4 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) BtpA PF03437.10 KFM08721.1 - 8.5e-35 120.2 0.1 9.1e-35 120.1 0.0 1.0 1 0 0 1 1 1 1 BtpA family Cyclin_N PF00134.18 KFM08722.1 - 2.3e-40 137.0 1.5 3.8e-40 136.3 1.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFM08722.1 - 5.5e-11 42.4 0.4 2e-10 40.6 0.0 2.1 2 1 1 3 3 3 1 Cyclin, C-terminal domain Prefoldin PF02996.12 KFM08723.1 - 1.9e-16 59.7 1.4 4.1e-16 58.7 0.0 2.3 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_3 PF13758.1 KFM08723.1 - 2.7e-09 36.7 1.3 1.4e-08 34.3 0.0 2.7 2 1 0 2 2 2 1 Prefoldin subunit DUF3835 PF12927.2 KFM08723.1 - 0.16 12.9 0.3 0.16 12.9 0.2 4.2 6 0 0 6 6 6 0 Domain of unknown function (DUF3835) Yae1_N PF09811.4 KFM08724.1 - 1.3e-14 53.4 41.7 3.4e+03 -2.4 28.9 4.0 1 1 0 1 1 1 0 Essential protein Yae1, N terminal zf-C2H2 PF00096.21 KFM08725.1 - 8.8e-30 101.2 74.2 2.4e-05 24.4 2.4 10.6 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM08725.1 - 9.8e-27 91.2 70.7 0.00084 19.5 1.6 10.6 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFM08725.1 - 3.4e-24 83.8 82.2 1.9e-08 34.1 1.7 12.8 13 0 0 13 13 12 7 Zinc-finger double domain zf-Di19 PF05605.7 KFM08725.1 - 8.1e-07 29.0 50.0 0.015 15.3 0.7 8.1 6 3 1 7 7 7 4 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 KFM08725.1 - 0.00012 22.0 7.2 0.0016 18.5 1.8 10.0 10 0 0 10 10 10 4 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.2 KFM08725.1 - 0.0023 18.0 42.0 3.5 7.7 0.1 10.0 5 3 3 9 9 9 2 C2H2 type zinc-finger (2 copies) GAGA PF09237.6 KFM08725.1 - 0.0023 17.4 13.5 0.58 9.7 0.1 6.3 6 2 2 8 8 8 2 GAGA factor zf-C2H2_jaz PF12171.3 KFM08725.1 - 0.061 13.4 0.3 0.061 13.4 0.2 9.3 9 0 0 9 9 9 0 Zinc-finger double-stranded RNA-binding C1_3 PF07649.7 KFM08725.1 - 1.6 8.8 15.8 3.9 7.6 0.1 5.3 5 0 0 5 5 5 0 C1-like domain TerY-C PF15616.1 KFM08725.1 - 1.7 8.5 11.5 4.7 7.1 0.1 3.8 4 0 0 4 4 4 0 TerY-C metal binding domain zf-CHCC PF10276.4 KFM08725.1 - 1.8 8.4 27.1 0.7 9.7 0.1 6.4 6 0 0 6 6 6 0 Zinc-finger domain Rad50_zn_hook PF04423.9 KFM08725.1 - 1.8 8.0 13.8 1.5 8.3 0.1 5.6 5 0 0 5 5 5 0 Rad50 zinc hook motif zf-C2H2_2 PF12756.2 KFM08726.1 - 1.4e-10 41.1 20.7 0.0041 17.2 0.8 5.2 3 2 1 4 4 4 4 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 KFM08726.1 - 1.8e-08 34.2 27.4 0.07 13.5 1.0 5.7 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM08726.1 - 5.9e-07 29.3 17.3 0.052 13.8 1.6 5.7 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM08726.1 - 1e-05 25.2 16.5 0.14 12.1 0.4 5.2 5 0 0 5 5 5 3 C2H2-type zinc finger zf-met PF12874.2 KFM08726.1 - 0.00072 19.6 7.2 0.021 14.9 1.5 3.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type DUF678 PF05077.7 KFM08726.1 - 0.0011 18.8 1.3 3.5 7.6 0.0 3.8 3 0 0 3 3 3 2 Protein of unknown function (DUF678) DUF3222 PF11519.3 KFM08726.1 - 0.06 13.3 0.0 0.2 11.6 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3222) Homeobox PF00046.24 KFM08726.1 - 0.094 12.3 0.4 0.38 10.4 0.1 2.3 2 0 0 2 2 2 0 Homeobox domain zf-C2H2_jaz PF12171.3 KFM08726.1 - 0.13 12.4 16.1 0.21 11.7 0.7 4.5 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding PyrI_C PF02748.10 KFM08726.1 - 0.2 11.1 2.2 2.3 7.7 0.1 3.1 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-AN1 PF01428.11 KFM08726.1 - 0.42 10.5 5.4 0.53 10.1 0.1 3.3 3 0 0 3 3 3 0 AN1-like Zinc finger zf-H2C2_2 PF13465.1 KFM08726.1 - 1.1 9.7 14.0 1.2 9.6 0.1 5.0 5 0 0 5 5 4 0 Zinc-finger double domain Zn-ribbon_8 PF09723.5 KFM08726.1 - 1.1 9.2 12.1 4.8 7.2 0.0 4.9 5 0 0 5 5 5 0 Zinc ribbon domain zinc_ribbon_4 PF13717.1 KFM08726.1 - 9.1 6.0 7.4 33 4.2 0.0 3.9 4 0 0 4 4 4 0 zinc-ribbon domain zf-C2H2_4 PF13894.1 KFM08727.1 - 5.7e-14 51.3 72.2 0.00058 20.0 1.4 9.7 9 0 0 9 9 9 8 C2H2-type zinc finger zf-C2H2 PF00096.21 KFM08727.1 - 4.6e-10 39.2 78.2 0.045 14.1 2.7 9.6 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM08727.1 - 3.1e-09 36.6 73.7 0.00032 20.8 1.3 11.3 11 1 0 11 11 11 6 Zinc-finger double domain zf-H2C2_5 PF13909.1 KFM08727.1 - 1.6e-07 31.1 74.8 0.011 15.8 0.1 9.9 9 0 0 9 9 9 6 C2H2-type zinc-finger domain AKAP95 PF04988.7 KFM08727.1 - 0.67 9.7 35.7 0.14 11.9 0.2 6.9 6 1 1 7 7 7 0 A-kinase anchoring protein 95 (AKAP95) GAGA PF09237.6 KFM08727.1 - 8.8 6.0 9.4 0.56 9.8 0.3 3.2 3 0 0 3 3 3 0 GAGA factor Dpy19 PF10034.4 KFM08728.1 - 2.7e-224 746.1 28.2 3.1e-224 745.9 19.6 1.0 1 0 0 1 1 1 1 Q-cell neuroblast polarisation Cadherin PF00028.12 KFM08729.1 - 9.6e-216 698.8 20.0 8e-20 70.9 0.2 15.3 15 0 0 15 15 15 15 Cadherin domain Laminin_G_2 PF02210.19 KFM08729.1 - 7.7e-39 132.6 0.1 1.1e-21 77.1 0.0 2.9 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.18 KFM08729.1 - 4.3e-27 94.7 0.0 1.2e-12 48.0 0.0 2.6 2 0 0 2 2 2 2 Laminin G domain Cadherin_C PF01049.12 KFM08729.1 - 4.6e-11 42.9 0.1 1.1e-10 41.7 0.1 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic region EGF PF00008.22 KFM08729.1 - 3.1e-10 39.8 51.6 8.2e-06 25.6 4.0 5.0 4 0 0 4 4 4 4 EGF-like domain Cadherin_2 PF08266.7 KFM08729.1 - 6.6e-10 38.4 0.0 0.11 12.1 0.0 7.1 9 0 0 9 9 9 3 Cadherin-like EGF_2 PF07974.8 KFM08729.1 - 0.0051 16.9 5.5 0.0051 16.9 3.8 5.6 6 0 0 6 6 6 2 EGF-like domain hEGF PF12661.2 KFM08729.1 - 0.0058 16.6 5.6 0.0058 16.6 3.9 5.0 4 0 0 4 4 4 3 Human growth factor-like EGF Laminin_EGF PF00053.19 KFM08729.1 - 3.7 7.5 49.1 0.56 10.1 2.7 4.6 3 1 0 3 3 3 0 Laminin EGF-like (Domains III and V) dsDNA_bind PF01984.15 KFM08730.1 - 2e-30 104.9 3.3 2.3e-30 104.7 2.3 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Methyltransf_4 PF02390.12 KFM08730.1 - 0.11 11.5 0.2 0.22 10.5 0.0 1.5 1 1 0 1 1 1 0 Putative methyltransferase PCI PF01399.22 KFM08730.1 - 0.11 12.8 0.1 0.16 12.2 0.0 1.3 1 1 0 1 1 1 0 PCI domain ORMDL PF04061.9 KFM08731.1 - 4.9e-53 178.3 1.8 5.6e-53 178.1 1.3 1.0 1 0 0 1 1 1 1 ORMDL family SAP PF02037.22 KFM08732.1 - 3.2e-10 39.2 4.5 5.4e-09 35.3 0.7 2.8 3 0 0 3 3 3 1 SAP domain LETM1 PF07766.8 KFM08732.1 - 0.095 11.7 0.1 0.095 11.7 0.1 1.7 2 0 0 2 2 2 0 LETM1-like protein Ribosomal_S8 PF00410.14 KFM08732.1 - 0.22 11.3 1.6 2.2 8.1 1.1 2.2 1 1 0 1 1 1 0 Ribosomal protein S8 Phage_B PF02304.10 KFM08732.1 - 0.25 11.6 2.1 0.29 11.4 0.2 2.0 1 1 1 2 2 2 0 Scaffold protein B HCMV_UL139 PF12507.3 KFM08732.1 - 0.9 9.7 5.1 8 6.6 0.2 2.8 1 1 1 2 2 2 0 Human Cytomegalovirus UL139 protein zf-C2H2_jaz PF12171.3 KFM08733.1 - 2.8e-06 27.2 8.8 1.5e-05 24.9 6.1 2.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Peptidase_S49_N PF08496.5 KFM08733.1 - 7.6 6.3 9.0 9.4 6.0 0.6 3.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Nup35_RRM PF05172.8 KFM08734.1 - 2.8e-27 94.4 0.1 4.6e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 KFM08734.1 - 1.7e-13 50.0 0.0 2.7e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.1 KFM08734.1 - 0.07 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DSPc PF00782.15 KFM08735.1 - 7.1e-32 109.7 0.0 8e-32 109.6 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFM08735.1 - 7.5e-05 22.1 0.0 8.5e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Nckap1 PF09735.4 KFM08736.1 - 0 1774.3 27.8 0 1774.1 19.2 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein NTR PF01759.16 KFM08737.1 - 8.1e-23 80.1 4.8 4.7e-22 77.6 0.3 2.0 1 1 1 2 2 2 2 UNC-6/NTR/C345C module Pneumo_matrix PF03393.11 KFM08737.1 - 0.048 12.5 0.8 0.064 12.1 0.5 1.1 1 0 0 1 1 1 0 Pneumovirus matrix protein Val_tRNA-synt_C PF10458.4 KFM08737.1 - 0.16 12.0 0.5 0.7 10.0 0.0 2.1 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Tubulin-binding PF00418.14 KFM08738.1 - 1.4e-64 213.3 21.8 5.3e-17 61.2 1.8 5.4 5 0 0 5 5 5 4 Tau and MAP protein, tubulin-binding repeat RII_binding_1 PF10522.4 KFM08738.1 - 0.042 13.9 3.5 0.13 12.4 2.4 1.9 1 0 0 1 1 1 0 RII binding domain DUF1880 PF08976.6 KFM08738.1 - 0.81 9.8 10.2 0.042 13.9 2.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) Ribul_P_3_epim PF00834.14 KFM08741.1 - 2.4e-45 154.1 0.1 3e-45 153.8 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.14 KFM08741.1 - 0.0017 17.9 0.0 0.0024 17.4 0.0 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain OMPdecase PF00215.19 KFM08741.1 - 0.0033 16.8 0.0 0.0045 16.4 0.0 1.3 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family TMP-TENI PF02581.12 KFM08741.1 - 0.0064 15.6 0.0 0.011 14.8 0.0 1.4 1 1 0 1 1 1 1 Thiamine monophosphate synthase/TENI His_biosynth PF00977.16 KFM08741.1 - 0.11 11.7 0.0 0.32 10.2 0.0 1.8 1 1 1 2 2 2 0 Histidine biosynthesis protein PG_binding_3 PF09374.5 KFM08741.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Predicted Peptidoglycan domain PEHE PF15275.1 KFM08742.1 - 4.3e-22 78.8 7.5 4.3e-22 78.8 5.2 4.1 5 0 0 5 5 5 1 PEHE domain Acyl-CoA_dh_1 PF00441.19 KFM08743.1 - 6.7e-42 143.1 0.1 9.3e-42 142.6 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KFM08743.1 - 8e-29 100.5 0.0 1.9e-28 99.3 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KFM08743.1 - 3.9e-19 67.8 0.5 3.7e-18 64.7 0.1 2.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KFM08743.1 - 2.2e-08 34.4 0.0 3.2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 KFM08743.1 - 0.018 15.3 0.1 0.042 14.1 0.0 1.7 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal EF-hand_7 PF13499.1 KFM08744.1 - 1.8e-12 47.2 0.3 3.3e-07 30.3 0.0 2.9 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 KFM08744.1 - 8.8e-12 43.8 0.8 0.00042 19.9 0.2 4.3 4 1 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 KFM08744.1 - 2.3e-11 42.1 3.8 0.019 14.2 0.0 5.0 4 2 2 6 6 6 3 EF hand EF-hand_8 PF13833.1 KFM08744.1 - 1.2e-06 28.0 1.5 0.036 13.6 0.1 3.7 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.1 KFM08744.1 - 0.0029 17.4 0.0 2.7 7.9 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain UPF0154 PF03672.8 KFM08744.1 - 0.019 14.5 0.0 2.4 7.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) DUF2267 PF10025.4 KFM08744.1 - 0.078 13.0 0.1 0.73 9.8 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) p25-alpha PF05517.7 KFM08744.1 - 0.1 12.8 0.1 1.8 8.8 0.1 2.3 1 1 1 2 2 2 0 p25-alpha LANC_like PF05147.8 KFM08745.1 - 3.1e-107 358.2 0.2 3.7e-107 357.9 0.2 1.1 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein DUF1680 PF07944.7 KFM08745.1 - 0.00061 18.1 1.0 0.25 9.5 0.2 2.3 2 1 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) Glyco_hydro_88 PF07470.8 KFM08745.1 - 0.00066 18.8 0.1 0.84 8.6 0.0 2.4 2 0 0 2 2 2 2 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.8 KFM08745.1 - 0.003 16.8 4.7 0.81 8.9 0.0 3.7 3 1 1 4 4 4 3 D-glucuronyl C5-epimerase C-terminus CPSase_L_D2 PF02786.12 KFM08746.1 - 3.6e-113 376.0 0.6 9.7e-82 273.3 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 KFM08746.1 - 1.1e-43 147.8 0.0 2.5e-43 146.7 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain CPSase_L_D3 PF02787.14 KFM08746.1 - 2e-39 134.1 0.1 4e-39 133.1 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 KFM08746.1 - 7.4e-36 122.6 0.0 6.9e-19 67.9 0.0 3.1 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain GATase PF00117.23 KFM08746.1 - 2.7e-35 121.5 0.0 4.9e-35 120.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I ATP-grasp_4 PF13535.1 KFM08746.1 - 2.5e-30 105.5 0.6 3.4e-17 62.7 0.1 2.3 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.17 KFM08746.1 - 1.2e-19 69.9 0.0 3.3e-18 65.3 0.0 2.7 2 0 0 2 2 2 1 MGS-like domain ATP-grasp PF02222.17 KFM08746.1 - 1.2e-17 63.7 0.4 1.5e-08 34.2 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 KFM08746.1 - 3.3e-16 58.9 0.0 1.2e-07 30.7 0.0 3.7 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KFM08746.1 - 6.3e-13 48.5 0.8 4.7e-06 26.1 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 KFM08746.1 - 6.1e-06 26.1 0.2 0.017 14.9 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.6 KFM08746.1 - 0.0011 18.5 0.1 0.55 9.6 0.0 2.6 2 1 0 2 2 2 2 RimK-like ATP-grasp domain DUF977 PF06163.6 KFM08746.1 - 0.08 12.6 0.1 0.47 10.2 0.0 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF977) Pkinase_Tyr PF07714.12 KFM08747.1 - 1.6e-91 305.9 0.0 2.9e-91 305.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Recep_L_domain PF01030.19 KFM08747.1 - 9.3e-58 193.0 4.6 5e-30 103.7 0.2 2.5 2 0 0 2 2 2 2 Receptor L domain GF_recep_IV PF14843.1 KFM08747.1 - 5.8e-53 178.0 82.8 2.4e-47 159.8 20.1 3.9 2 1 1 3 3 3 3 Growth factor receptor domain IV Pkinase PF00069.20 KFM08747.1 - 1.1e-41 142.7 0.0 1.7e-41 142.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Furin-like PF00757.15 KFM08747.1 - 1.8e-35 121.7 88.2 8.6e-29 100.1 29.4 4.4 2 1 2 4 4 4 3 Furin-like cysteine rich region APH PF01636.18 KFM08747.1 - 0.0047 16.6 0.1 0.0087 15.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KFM08747.1 - 0.01 14.8 0.0 0.022 13.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Adeno_E3_CR2 PF02439.10 KFM08747.1 - 0.22 11.0 2.1 0.56 9.8 1.5 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 LRR_8 PF13855.1 KFM08748.1 - 2.4e-68 225.7 47.6 1.2e-14 53.7 0.9 7.6 3 1 4 7 7 7 7 Leucine rich repeat I-set PF07679.11 KFM08748.1 - 1.4e-49 165.8 0.0 1.5e-19 69.5 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain LRR_4 PF12799.2 KFM08748.1 - 2.3e-41 138.8 53.1 1.9e-07 30.5 0.9 9.4 3 2 7 10 10 10 10 Leucine Rich repeats (2 copies) Ig_2 PF13895.1 KFM08748.1 - 1.8e-33 114.4 0.0 1.5e-10 41.0 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain LRR_5 PF13306.1 KFM08748.1 - 4.5e-28 97.5 3.1 5.4e-11 42.3 0.0 4.1 1 1 3 4 4 4 4 Leucine rich repeats (6 copies) LRR_1 PF00560.28 KFM08748.1 - 2.5e-25 84.6 37.9 0.014 15.2 0.5 16.4 16 1 0 16 16 16 7 Leucine Rich Repeat Ig_3 PF13927.1 KFM08748.1 - 3.6e-21 75.4 0.0 7.2e-06 26.4 0.0 4.5 3 2 0 3 3 3 3 Immunoglobulin domain ig PF00047.20 KFM08748.1 - 4.3e-17 61.9 0.0 6.3e-06 26.2 0.0 4.4 3 2 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 KFM08748.1 - 5.1e-13 48.9 0.1 0.0066 16.3 0.0 4.1 2 1 0 3 3 3 3 Immunoglobulin V-set domain LRR_9 PF14580.1 KFM08748.1 - 1.1e-11 44.5 14.8 0.011 15.2 0.3 5.4 1 1 5 6 6 6 4 Leucine-rich repeat LRR_7 PF13504.1 KFM08748.1 - 7.9e-09 34.3 39.3 0.27 11.5 0.3 14.1 14 0 0 14 14 14 1 Leucine rich repeat LRR_6 PF13516.1 KFM08748.1 - 2.1e-08 33.3 52.2 0.033 14.2 0.7 14.3 13 3 2 15 15 15 3 Leucine Rich repeat C2-set_2 PF08205.7 KFM08748.1 - 2.7e-08 33.5 0.0 0.011 15.5 0.0 3.6 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain C2-set PF05790.10 KFM08748.1 - 0.031 14.2 0.3 6.5 6.8 0.0 3.8 5 0 0 5 5 5 0 Immunoglobulin C2-set domain FNIP PF05725.7 KFM08748.1 - 4.7 7.2 11.2 19 5.3 2.6 4.2 3 1 0 3 3 3 0 FNIP Repeat MFS_1 PF07690.11 KFM08750.1 - 4.7e-39 134.1 38.8 4.5e-35 120.9 20.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KFM08750.1 - 9.8e-06 25.2 11.4 0.12 12.1 2.8 4.5 3 1 0 3 3 3 2 MFS_1 like family Sugar_tr PF00083.19 KFM08750.1 - 0.00059 18.5 10.4 0.00059 18.5 7.2 3.3 2 1 0 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.8 KFM08750.1 - 1.2 7.1 5.5 0.13 10.3 0.5 1.7 2 0 0 2 2 2 0 Transmembrane secretion effector Pardaxin PF07425.6 KFM08750.1 - 1.2 8.5 4.9 0.23 10.9 0.4 2.1 2 0 0 2 2 2 0 Pardaxin TAFA PF12020.3 KFM08751.1 - 5e-40 135.5 8.6 6.4e-40 135.1 5.9 1.1 1 0 0 1 1 1 1 TAFA family UCH PF00443.24 KFM08752.1 - 1.3e-93 312.9 0.0 2.8e-93 311.9 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_3 PF14836.1 KFM08752.1 - 4.1e-36 122.5 0.2 8.2e-36 121.5 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain UCH_1 PF13423.1 KFM08752.1 - 6.9e-24 84.8 0.0 8.3e-14 51.7 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 KFM08752.1 - 1.1e-18 67.4 0.8 1.1e-18 67.4 0.6 2.8 2 1 0 2 2 2 1 DUSP domain USP7_C2 PF14533.1 KFM08752.1 - 6.2e-08 32.3 0.3 1.3e-06 27.9 0.0 2.5 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal CW_binding_1 PF01473.15 KFM08752.1 - 0.059 13.5 5.0 0.34 11.1 3.5 2.3 1 0 0 1 1 1 0 Putative cell wall binding repeat Sec7_N PF12783.2 KFM08753.1 - 2.1e-27 95.5 9.1 3.8e-13 49.2 0.4 4.1 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KFM08753.1 - 1.4e-18 66.2 0.4 9e-17 60.3 0.0 3.8 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) HEAT PF02985.17 KFM08753.1 - 0.0016 18.3 0.5 17 5.8 0.0 5.1 4 0 0 4 4 4 1 HEAT repeat PP2C PF00481.16 KFM08754.1 - 2.7e-28 99.0 0.0 4.2e-12 45.9 0.0 3.0 3 0 0 3 3 3 3 Protein phosphatase 2C SpoIIE PF07228.7 KFM08754.1 - 2.3e-05 24.1 0.0 0.057 13.1 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 KFM08754.1 - 0.0002 20.8 0.0 0.0037 16.6 0.0 2.4 1 1 0 1 1 1 1 Protein phosphatase 2C Exostosin PF03016.10 KFM08755.1 - 0.0012 17.9 0.0 0.0018 17.3 0.0 1.3 1 0 0 1 1 1 1 Exostosin family DUF2827 PF10933.3 KFM08755.1 - 0.0037 15.8 0.0 0.0055 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2827) Flg_bbr_C PF06429.8 KFM08755.1 - 0.014 15.3 0.1 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 Flagellar basal body rod FlgEFG protein C-terminal RhoGAP PF00620.22 KFM08757.1 - 2.4e-46 157.1 0.3 2.5e-45 153.8 0.0 2.7 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 KFM08757.1 - 4.8e-19 68.3 6.1 2.5e-18 66.0 4.2 2.4 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 KFM08757.1 - 7.8e-11 41.3 0.0 1.3e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM08757.1 - 2.3e-10 39.7 0.0 4.4e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFM08757.1 - 4.6e-09 35.6 0.0 9.7e-09 34.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain FlaC_arch PF05377.6 KFM08757.1 - 0.0098 15.7 0.8 0.062 13.1 0.6 2.4 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) DUF2003 PF09404.5 KFM08758.1 - 1.6e-283 939.8 6.3 1.7e-283 939.7 4.4 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF2003) Herpes_UL55 PF04537.7 KFM08759.1 - 0.069 12.5 0.1 0.074 12.4 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL55 protein Ribosomal_L18ae PF01775.12 KFM08760.1 - 2.4e-57 192.1 0.1 3.1e-57 191.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain Xpo1 PF08389.7 KFM08761.1 - 1.9e-36 125.2 1.3 1.9e-36 125.2 0.9 4.4 4 1 0 4 4 4 2 Exportin 1-like protein Pkinase PF00069.20 KFM08762.1 - 5.7e-46 156.7 0.0 1.1e-45 155.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM08762.1 - 6.2e-22 77.9 0.0 1.2e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM08762.1 - 0.0018 17.2 0.0 0.021 13.7 0.0 2.3 2 0 0 2 2 2 1 Kinase-like ubiquitin PF00240.18 KFM08762.1 - 0.0038 16.6 0.2 0.016 14.5 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family NPV_P10 PF05531.7 KFM08762.1 - 0.038 14.2 1.5 1.2 9.4 0.4 3.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein APH PF01636.18 KFM08762.1 - 0.13 11.9 0.0 2.9 7.5 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family MULE PF10551.4 KFM08762.1 - 0.49 10.5 2.5 9.2 6.5 0.2 3.2 2 2 1 3 3 3 0 MULE transposase domain C1_1 PF00130.17 KFM08763.1 - 0.049 13.3 4.9 0.07 12.8 3.4 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Vanabin-2 PF11437.3 KFM08763.1 - 0.098 12.6 0.9 0.096 12.6 0.7 1.1 1 0 0 1 1 1 0 Vanadium-binding protein 2 RA PF00788.18 KFM08764.1 - 3.3e-24 85.1 0.2 4.5e-23 81.5 0.0 2.1 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain Ras_bdg_2 PF14847.1 KFM08764.1 - 0.023 14.6 0.0 0.059 13.3 0.0 1.7 1 0 0 1 1 1 0 Ras-binding domain of Byr2 Pepsin-I3 PF06394.8 KFM08764.1 - 1.4 8.6 5.0 1.2 8.8 0.5 2.6 3 0 0 3 3 3 0 Pepsin inhibitor-3-like repeated domain Sulfatase PF00884.18 KFM08765.1 - 1.4e-64 218.2 0.4 1.7e-64 217.9 0.3 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KFM08765.1 - 1.3e-09 37.8 0.1 0.00037 19.9 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KFM08765.1 - 0.016 13.6 0.0 0.047 12.1 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF229) RabGAP-TBC PF00566.13 KFM08766.1 - 1.7e-39 135.5 0.1 3.8e-39 134.3 0.1 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain 60KD_IMP PF02096.15 KFM08766.1 - 1.5 8.4 6.8 0.15 11.6 0.5 2.4 3 0 0 3 3 3 0 60Kd inner membrane protein WIF PF02019.13 KFM08767.1 - 1.4e-20 73.0 0.0 2e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 WIF domain EGF_2 PF07974.8 KFM08767.1 - 6.3e-19 67.8 91.7 0.00019 21.5 9.7 5.3 5 0 0 5 5 5 5 EGF-like domain hEGF PF12661.2 KFM08767.1 - 5.6e-16 57.4 49.1 0.00082 19.2 1.7 6.9 6 0 0 6 6 6 5 Human growth factor-like EGF EGF PF00008.22 KFM08767.1 - 1.1e-10 41.2 85.6 0.00015 21.6 5.2 5.7 5 0 0 5 5 5 5 EGF-like domain Laminin_EGF PF00053.19 KFM08767.1 - 1.5 8.8 72.3 4.9 7.1 6.7 5.3 1 1 4 5 5 5 0 Laminin EGF-like (Domains III and V) MSC PF09402.5 KFM08768.1 - 1.1e-50 172.3 0.4 1.7e-50 171.6 0.3 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain RRM_5 PF13893.1 KFM08768.1 - 0.0031 17.3 0.0 0.0083 15.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 KFM08768.1 - 0.048 13.9 0.9 0.19 12.0 0.0 2.4 3 0 0 3 3 3 0 linker between RRM2 and RRM3 domains in RBM39 protein DUF3227 PF11537.3 KFM08768.1 - 0.1 12.7 0.0 7.4 6.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3227) SelR PF01641.13 KFM08769.1 - 8.6e-52 174.0 0.1 1.1e-51 173.6 0.1 1.1 1 0 0 1 1 1 1 SelR domain DZR PF12773.2 KFM08769.1 - 0.058 13.2 0.5 0.51 10.1 0.4 2.4 1 1 1 2 2 2 0 Double zinc ribbon DUF2961 PF11175.3 KFM08769.1 - 0.058 12.6 0.1 0.079 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2961) Yippee-Mis18 PF03226.9 KFM08769.1 - 0.067 13.2 0.2 0.29 11.2 0.1 2.0 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly GFA PF04828.9 KFM08769.1 - 0.083 12.8 1.7 1.5 8.7 0.1 2.3 1 1 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-Mss51 PF13824.1 KFM08769.1 - 0.1 12.4 3.8 0.54 10.1 0.1 2.8 3 1 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 TF_Zn_Ribbon PF08271.7 KFM08769.1 - 0.11 11.7 0.7 15 5.0 0.0 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding Auto_anti-p27 PF06677.7 KFM08769.1 - 0.38 10.5 4.4 1.3 8.8 0.1 2.8 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-HIT PF04438.11 KFM08769.1 - 0.44 10.2 4.7 6 6.6 0.0 2.8 2 1 0 2 2 2 0 HIT zinc finger zf-tcix PF14952.1 KFM08769.1 - 2.4 7.5 6.3 14 5.1 0.1 3.2 3 0 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding AT_hook PF02178.14 KFM08771.1 - 0.0049 16.3 26.9 0.068 12.8 5.0 3.2 3 1 0 3 3 3 2 AT hook motif mono-CXXC PF15626.1 KFM08771.1 - 3.8 7.5 5.6 1.3 9.0 2.2 1.5 1 1 1 2 2 2 0 single CXXC unit Laps PF10169.4 KFM08772.1 - 1.1e-36 125.9 16.9 1.8e-36 125.2 11.7 1.3 1 1 0 1 1 1 1 Learning-associated protein DUF2423 PF10338.4 KFM08772.1 - 0.00061 19.6 7.5 0.00061 19.6 5.2 2.5 3 1 0 3 3 3 1 Protein of unknown function (DUF2423) Bax1-I PF01027.15 KFM08773.1 - 1.7e-46 158.3 29.2 2e-46 158.2 20.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 7TMR-DISM_7TM PF07695.6 KFM08773.1 - 0.6 9.7 30.0 2 8.0 7.5 2.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling Transport_MerF PF11431.3 KFM08773.1 - 2.4 7.8 10.5 10 5.8 0.0 4.2 4 0 0 4 4 4 0 Membrane transport protein MerF Oxidored_q1_N PF00662.15 KFM08773.1 - 4.9 6.7 7.4 0.44 10.1 1.2 2.2 2 0 0 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus AAA_30 PF13604.1 KFM08774.1 - 2e-23 83.0 0.0 9.6e-23 80.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 KFM08774.1 - 4.4e-11 42.8 0.2 1.2e-10 41.4 0.1 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 KFM08774.1 - 4.9e-11 42.6 1.7 0.0033 16.9 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 KFM08774.1 - 5.4e-07 29.2 0.0 1.6e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain ABC_tran PF00005.22 KFM08774.1 - 7e-05 23.1 0.0 0.00032 21.0 0.0 2.2 1 0 0 1 1 1 1 ABC transporter AAA_11 PF13086.1 KFM08774.1 - 0.0002 21.0 0.4 0.69 9.4 0.0 2.5 1 1 1 2 2 2 2 AAA domain CbiA PF01656.18 KFM08774.1 - 0.0017 17.7 0.0 0.0033 16.8 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF258 PF03193.11 KFM08774.1 - 0.002 17.3 0.1 0.0048 16.1 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 KFM08774.1 - 0.0028 18.0 0.0 0.011 16.0 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFM08774.1 - 0.0038 17.2 0.0 0.019 14.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 KFM08774.1 - 0.0047 16.8 0.0 0.074 12.9 0.0 3.0 2 1 1 3 3 3 1 AAA domain Arch_ATPase PF01637.13 KFM08774.1 - 0.0075 16.0 0.0 0.081 12.6 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase AAA_5 PF07728.9 KFM08774.1 - 0.029 14.0 0.0 7.8 6.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KFM08774.1 - 0.03 14.4 0.4 0.63 10.1 0.1 3.1 3 1 0 3 3 3 0 AAA domain ArsA_ATPase PF02374.10 KFM08774.1 - 0.044 12.8 1.1 0.39 9.7 0.3 2.7 2 1 1 3 3 3 0 Anion-transporting ATPase AAA_29 PF13555.1 KFM08774.1 - 0.076 12.5 0.3 0.28 10.7 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain PDZ PF00595.19 KFM08775.1 - 5e-91 298.9 7.6 3.6e-14 52.7 0.0 7.2 7 0 0 7 7 7 7 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM08775.1 - 1.2e-37 127.6 4.2 1.4e-06 28.1 0.0 7.4 7 0 0 7 7 7 7 PDZ domain Tricorn_PDZ PF14685.1 KFM08775.1 - 2.6e-14 52.7 1.0 0.028 14.2 0.0 6.4 6 0 0 6 6 6 4 Tricorn protease PDZ domain GRASP55_65 PF04495.9 KFM08775.1 - 0.00024 21.0 0.1 4.4 7.2 0.0 4.1 2 2 1 4 4 4 2 GRASP55/65 PDZ-like domain MoaE PF02391.12 KFM08775.1 - 0.0039 16.9 0.4 15 5.3 0.0 4.2 4 0 0 4 4 4 1 MoaE protein EutA PF06277.6 KFM08775.1 - 0.019 13.5 1.6 0.34 9.4 0.1 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation protein EutA FTH PF01827.22 KFM08775.1 - 0.094 12.3 0.0 0.82 9.2 0.0 2.4 3 0 0 3 3 3 0 FTH domain SPO22 PF08631.5 KFM08775.1 - 0.095 11.7 0.0 12 4.9 0.0 2.3 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like Dynamin_M PF01031.15 KFM08776.1 - 1.8e-101 338.8 5.2 3.4e-101 337.9 2.1 2.3 3 0 0 3 3 3 1 Dynamin central region Dynamin_N PF00350.18 KFM08776.1 - 4e-42 143.8 0.0 1.1e-41 142.4 0.0 1.8 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KFM08776.1 - 3.8e-25 87.6 1.6 9.3e-25 86.3 1.1 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain PH PF00169.24 KFM08776.1 - 3.2e-11 43.3 0.6 6.5e-11 42.3 0.4 1.5 1 0 0 1 1 1 1 PH domain KcnmB2_inactiv PF09303.5 KFM08776.1 - 0.079 12.7 0.0 0.24 11.2 0.0 1.8 1 0 0 1 1 1 0 KCNMB2, ball and chain domain Keratin PF02422.11 KFM08778.1 - 1.3e-43 146.8 17.8 1.5e-43 146.7 12.3 1.0 1 0 0 1 1 1 1 Keratin LRR_8 PF13855.1 KFM08779.1 - 3.4e-41 138.7 37.1 7.4e-13 48.0 2.5 5.8 2 1 4 6 6 6 5 Leucine rich repeat LRR_4 PF12799.2 KFM08779.1 - 1.4e-22 78.8 31.9 2.8e-07 29.9 0.2 6.6 3 2 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFM08779.1 - 7.5e-18 64.4 0.1 2e-11 43.6 0.1 2.5 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) I-set PF07679.11 KFM08779.1 - 1.5e-16 59.9 0.0 2.5e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_1 PF00560.28 KFM08779.1 - 6.9e-13 46.7 31.7 0.02 14.8 0.0 10.7 11 0 0 11 11 11 3 Leucine Rich Repeat Ig_2 PF13895.1 KFM08779.1 - 7.3e-08 32.4 0.0 1.6e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain LRR_6 PF13516.1 KFM08779.1 - 2.3e-07 30.1 20.8 2.1 8.6 0.0 8.9 7 1 1 8 8 8 1 Leucine Rich repeat Ig_3 PF13927.1 KFM08779.1 - 6e-07 29.8 0.0 3.8e-06 27.3 0.0 2.4 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFM08779.1 - 7.8e-07 28.9 0.0 6e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin V-set domain ig PF00047.20 KFM08779.1 - 2.1e-05 24.5 0.0 5.5e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain LRRCT PF01463.19 KFM08779.1 - 0.001 19.1 1.9 0.68 10.4 0.1 4.0 3 1 0 3 3 3 1 Leucine rich repeat C-terminal domain LRRNT PF01462.13 KFM08779.1 - 0.0075 15.7 3.4 0.0075 15.7 2.3 3.0 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_7 PF13504.1 KFM08779.1 - 0.013 15.6 28.1 7.6 7.2 0.1 9.6 10 0 0 10 10 10 0 Leucine rich repeat SEA PF01390.15 KFM08781.1 - 7.3e-14 51.3 0.0 8.1e-14 51.2 0.0 1.0 1 0 0 1 1 1 1 SEA domain SEA PF01390.15 KFM08782.1 - 8.9e-15 54.3 0.1 9.9e-15 54.1 0.1 1.0 1 0 0 1 1 1 1 SEA domain Phage_T4_Ndd PF06591.6 KFM08782.1 - 0.088 12.3 0.0 0.099 12.2 0.0 1.2 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) ADAM_spacer1 PF05986.9 KFM08783.1 - 9.1e-33 112.5 0.0 1.6e-32 111.7 0.0 1.4 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Pep_M12B_propep PF01562.14 KFM08783.1 - 2e-27 95.5 0.1 3.5e-27 94.7 0.1 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide TSP_1 PF00090.14 KFM08783.1 - 2.5e-15 56.3 88.9 7.2e-07 29.2 5.4 8.1 8 1 0 8 8 8 5 Thrombospondin type 1 domain Reprolysin PF01421.14 KFM08783.1 - 5.7e-11 42.3 2.1 5.7e-11 42.3 1.4 2.6 2 1 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease PLAC PF08686.6 KFM08783.1 - 1.2e-10 41.4 9.8 4.8e-10 39.5 6.8 2.2 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain zf-H2C2_5 PF13909.1 KFM08784.1 - 0.00014 21.8 0.6 0.00024 21.1 0.4 1.4 1 0 0 1 1 1 1 C2H2-type zinc-finger domain LRR_4 PF12799.2 KFM08785.1 - 4.1e-14 51.8 21.8 1.1e-08 34.4 3.9 3.0 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM08785.1 - 1.6e-09 37.3 21.2 3.6e-07 29.8 3.1 2.7 1 1 2 3 3 3 3 Leucine rich repeat LRR_9 PF14580.1 KFM08785.1 - 1.5e-08 34.3 0.2 2.1e-08 33.9 0.2 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_7 PF13504.1 KFM08785.1 - 2.5e-06 26.7 11.7 0.2 11.9 0.2 5.5 6 0 0 6 6 6 3 Leucine rich repeat LRR_6 PF13516.1 KFM08785.1 - 6.1e-06 25.7 11.9 0.0049 16.8 0.4 4.5 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.28 KFM08785.1 - 0.00038 20.0 14.7 0.018 14.9 0.3 4.9 5 0 0 5 5 5 2 Leucine Rich Repeat AMP-binding PF00501.23 KFM08786.1 - 2.5e-80 269.9 0.0 3.1e-80 269.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme RFX1_trans_act PF04589.8 KFM08787.1 - 4.9e-64 214.7 21.2 4.9e-64 214.7 14.7 2.9 3 0 0 3 3 3 1 RFX1 transcription activation region RFX_DNA_binding PF02257.10 KFM08787.1 - 4e-39 132.6 0.1 1.8e-38 130.5 0.1 2.2 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.11 KFM08787.1 - 0.039 14.2 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Poxvirus D5 protein-like La PF05383.12 KFM08788.1 - 3.7e-21 74.6 0.9 5.5e-21 74.1 0.6 1.3 1 0 0 1 1 1 1 La domain RRM_5 PF13893.1 KFM08788.1 - 0.0011 18.7 0.0 0.01 15.6 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFM08788.1 - 0.0071 15.9 0.0 1.6 8.4 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNR_N PF08343.5 KFM08788.1 - 0.086 12.6 0.1 0.22 11.3 0.1 1.7 1 0 0 1 1 1 0 Ribonucleotide reductase N-terminal Dus PF01207.12 KFM08789.1 - 7.2e-56 189.2 0.0 1e-55 188.8 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 KFM08789.1 - 0.0045 16.6 16.0 0.033 13.8 1.0 3.4 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) FMN_dh PF01070.13 KFM08789.1 - 0.0074 15.1 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase PEP_mutase PF13714.1 KFM08789.1 - 0.0092 15.2 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase CDC45 PF02724.9 KFM08789.1 - 9 4.1 7.0 13 3.6 4.9 1.1 1 0 0 1 1 1 0 CDC45-like protein TGF_beta PF00019.15 KFM08790.1 - 8.6e-20 70.9 0.9 1.3e-19 70.4 0.6 1.3 1 0 0 1 1 1 1 Transforming growth factor beta like domain BNIP2 PF12496.3 KFM08791.1 - 1.3e-40 138.4 0.2 1.8e-40 138.0 0.1 1.2 1 0 0 1 1 1 1 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 CRAL_TRIO_2 PF13716.1 KFM08791.1 - 1.6e-30 105.9 0.1 2.2e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 KFM08791.1 - 6.7e-08 32.1 0.2 9.7e-08 31.6 0.2 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain AAA_18 PF13238.1 KFM08792.1 - 1.4e-10 41.6 0.0 2.4e-10 40.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFM08792.1 - 0.0027 18.5 0.0 0.0061 17.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFM08792.1 - 0.013 15.3 0.0 0.15 11.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain Pkinase PF00069.20 KFM08793.1 - 4.4e-70 235.7 0.0 4.9e-70 235.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM08793.1 - 2e-34 118.8 0.0 2.3e-34 118.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFM08793.1 - 2.1e-06 26.9 0.1 3.7e-06 26.1 0.1 1.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFM08793.1 - 5.9e-06 25.7 0.1 8.7e-06 25.2 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 KFM08793.1 - 0.011 15.3 0.1 0.019 14.5 0.1 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase Glycos_trans_3N PF02885.12 KFM08793.1 - 0.022 14.3 0.2 0.081 12.5 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain APH PF01636.18 KFM08793.1 - 0.098 12.3 0.1 0.43 10.2 0.0 1.8 1 1 0 2 2 2 0 Phosphotransferase enzyme family GTP_EFTU PF00009.22 KFM08794.1 - 8.9e-61 204.6 0.0 1.2e-60 204.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KFM08794.1 - 1.1e-38 131.4 0.1 2.9e-38 130.0 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 KFM08794.1 - 1.5e-22 79.2 0.0 3.7e-22 78.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 KFM08794.1 - 2.2e-13 49.8 0.0 5e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 KFM08794.1 - 1.4e-12 47.5 0.3 1e-11 44.7 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KFM08794.1 - 1.4e-05 24.9 0.0 3e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PINIT PF14324.1 KFM08795.1 - 4.9e-39 133.6 0.6 8.2e-39 132.9 0.4 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 KFM08795.1 - 2.3e-21 75.0 5.7 5.8e-21 73.7 3.9 1.8 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.22 KFM08795.1 - 1.1e-05 24.8 0.1 5.5e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 SAP domain zf-Nse PF11789.3 KFM08795.1 - 0.00027 20.3 1.9 0.00027 20.3 1.3 1.7 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit CENP-B_dimeris PF09026.5 KFM08795.1 - 3.6 7.8 8.6 6.7 7.0 6.0 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pkinase PF00069.20 KFM08796.1 - 5.7e-60 202.6 0.0 7e-60 202.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM08796.1 - 4.3e-34 117.7 0.0 2e-32 112.2 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KFM08796.1 - 0.00052 19.0 0.0 0.001 18.1 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KFM08796.1 - 0.013 15.2 0.0 0.027 14.1 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KFM08796.1 - 0.025 13.4 0.0 0.039 12.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 SIR2 PF02146.12 KFM08797.1 - 3.3e-25 88.8 0.0 1.8e-17 63.6 0.0 2.1 1 1 1 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.17 KFM08797.1 - 0.0012 18.5 0.0 0.38 10.5 0.0 2.2 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain EGF_CA PF07645.10 KFM08798.1 - 0 1033.9 750.7 5.1e-11 42.3 3.5 49.7 48 2 3 51 51 51 44 Calcium-binding EGF domain cEGF PF12662.2 KFM08798.1 - 4.2e-194 627.3 421.2 1.6e-08 33.9 0.1 50.2 50 0 0 50 50 50 45 Complement Clr-like EGF-like EGF PF00008.22 KFM08798.1 - 7e-126 409.3 650.8 1.8e-05 24.5 3.5 49.6 47 0 0 47 47 47 45 EGF-like domain TB PF00683.12 KFM08798.1 - 9.4e-119 386.7 130.2 1.6e-14 53.1 4.0 11.2 9 0 0 9 9 9 9 TB domain FXa_inhibition PF14670.1 KFM08798.1 - 5e-104 340.0 717.7 5.1e-08 32.8 8.0 49.2 45 3 3 48 48 48 43 Coagulation Factor Xa inhibitory site EGF_3 PF12947.2 KFM08798.1 - 2.8e-45 151.9 626.8 2.7e-09 36.8 3.8 49.3 48 0 0 48 48 48 39 EGF domain Cortexin PF11057.3 KFM08799.1 - 9e-40 134.1 0.1 9.2e-40 134.1 0.1 1.0 1 0 0 1 1 1 1 Cortexin of kidney Ca_hom_mod PF14798.1 KFM08799.1 - 0.018 13.9 0.0 0.019 13.9 0.0 1.0 1 0 0 1 1 1 0 Calcium homeostasis modulator DUF3317 PF11779.3 KFM08799.1 - 0.077 12.4 0.2 0.11 11.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3317) DUF2701 PF10857.3 KFM08799.1 - 0.15 11.8 2.9 0.19 11.5 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2701) Tim44 PF04280.10 KFM08800.1 - 4.4e-40 137.0 0.3 1.9e-39 134.9 0.0 2.1 2 0 0 2 2 2 1 Tim44-like domain Prominin PF05478.6 KFM08800.1 - 0.021 12.4 0.5 0.028 11.9 0.4 1.1 1 0 0 1 1 1 0 Prominin MscS_porin PF12795.2 KFM08800.1 - 0.37 10.0 6.1 0.59 9.4 4.2 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain SseC PF04888.7 KFM08800.1 - 4.4 6.5 12.7 0.11 11.8 1.9 2.3 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family RRM_1 PF00076.17 KFM08801.1 - 4.5e-54 179.9 0.1 3.8e-19 68.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM08801.1 - 5.8e-34 115.8 0.8 2.4e-11 43.4 0.0 3.7 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM08801.1 - 5e-22 77.5 0.2 1e-06 28.4 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNP_M PF11532.3 KFM08801.1 - 5.7e-15 55.1 8.9 1.3e-14 53.9 6.1 1.7 1 0 0 1 1 1 1 Heterogeneous nuclear ribonucleoprotein M Limkain-b1 PF11608.3 KFM08801.1 - 3.5e-06 26.6 0.4 0.0009 18.9 0.0 2.6 2 0 0 2 2 2 2 Limkain b1 RRM_3 PF08777.6 KFM08801.1 - 3.9e-05 23.4 0.3 0.057 13.2 0.0 2.9 3 0 0 3 3 3 2 RNA binding motif DUF3932 PF13068.1 KFM08801.1 - 0.11 12.6 0.0 2.4 8.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3932) DUF572 PF04502.8 KFM08802.1 - 3.7e-93 312.3 19.1 4.1e-93 312.1 13.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Benyvirus_14KDa PF07255.6 KFM08802.1 - 0.088 12.6 0.2 1.4 8.8 0.0 2.1 1 1 1 2 2 2 0 Benyvirus 14KDa protein DUF1436 PF07262.6 KFM08802.1 - 4.2 6.8 7.2 0.37 10.2 1.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1436) Autophagy_N PF03986.8 KFM08802.1 - 4.3 7.0 9.1 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 Autophagocytosis associated protein (Atg3), N-terminal domain PI3Ka PF00613.15 KFM08803.1 - 5.5e-59 198.4 1.4 1.1e-58 197.4 0.9 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 KFM08803.1 - 7.4e-52 176.1 0.0 2.2e-50 171.3 0.0 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 KFM08803.1 - 1.1e-45 154.9 0.0 2e-45 154.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.1 KFM08803.1 - 5.9e-05 22.2 0.0 0.00076 18.5 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4135) HEAT_2 PF13646.1 KFM08803.1 - 0.032 14.5 0.1 0.081 13.2 0.0 1.7 1 0 0 1 1 1 0 HEAT repeats Spo0A_C PF08769.6 KFM08803.1 - 0.034 14.0 0.1 0.076 12.8 0.1 1.5 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal Ras PF00071.17 KFM08804.1 - 1.2e-42 145.0 0.0 1.4e-42 144.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM08804.1 - 1.5e-11 44.8 0.0 2.6e-11 44.0 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFM08804.1 - 4e-05 22.9 0.0 5.1e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFM08804.1 - 0.00068 19.1 0.0 0.00089 18.7 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 KFM08804.1 - 0.0059 16.1 0.0 0.0068 15.9 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein NADH_Oxid_Nqo15 PF11497.3 KFM08804.1 - 0.07 12.8 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 NADH-quinone oxidoreductase chain 15 C2 PF00168.25 KFM08806.1 - 8.2e-46 153.7 0.1 2.1e-22 78.7 0.0 2.5 2 0 0 2 2 2 2 C2 domain PTEN_C2 PF10409.4 KFM08806.1 - 0.0087 15.7 0.1 0.025 14.3 0.0 1.8 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein CEP76-C2 PF15627.1 KFM08806.1 - 0.073 12.5 0.1 7.6 6.0 0.0 2.4 2 0 0 2 2 2 0 CEP76 C2 domain AT_hook PF02178.14 KFM08808.1 - 0.93 9.3 38.1 0.086 12.5 1.1 5.1 4 0 0 4 4 4 0 AT hook motif UT PF03253.9 KFM08809.1 - 2.2e-230 762.2 66.9 3.2e-116 387.4 19.7 2.0 2 0 0 2 2 2 2 Urea transporter V-set PF07686.12 KFM08810.1 - 3.1e-12 46.3 0.4 2.9e-11 43.2 0.0 2.3 2 1 0 2 2 2 1 Immunoglobulin V-set domain Ig_2 PF13895.1 KFM08810.1 - 5.2e-11 42.5 0.5 1.9e-05 24.6 0.2 2.5 1 1 1 2 2 2 2 Immunoglobulin domain I-set PF07679.11 KFM08810.1 - 4e-09 36.1 0.2 0.00016 21.4 0.1 3.5 3 1 0 3 3 3 2 Immunoglobulin I-set domain Ig_3 PF13927.1 KFM08810.1 - 5.2e-05 23.6 6.5 0.002 18.6 0.6 3.2 2 2 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 KFM08810.1 - 0.0022 18.0 4.0 0.027 14.5 0.0 3.4 3 1 0 3 3 3 1 Immunoglobulin domain C2-set_2 PF08205.7 KFM08810.1 - 0.019 14.8 0.1 0.096 12.5 0.0 2.1 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain Pkinase PF00069.20 KFM08811.1 - 2.2e-49 167.9 0.0 3e-49 167.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM08811.1 - 1.5e-15 57.0 0.0 2.1e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM08811.1 - 1.1e-07 31.1 0.0 1.3e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFM08811.1 - 0.00031 19.8 0.0 0.00049 19.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFM08811.1 - 0.011 15.0 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 KFM08811.1 - 0.025 14.3 0.1 0.095 12.4 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-ZPR1 PF03367.8 KFM08811.1 - 0.079 12.1 0.0 9 5.4 0.0 2.2 2 0 0 2 2 2 0 ZPR1 zinc-finger domain Peptidase_C1 PF00112.18 KFM08812.1 - 1e-78 264.1 6.6 6.9e-78 261.4 4.5 1.9 1 1 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 KFM08812.1 - 7e-12 45.4 0.0 1.2e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 KFM08812.1 - 0.0079 14.7 1.6 0.036 12.5 0.1 2.2 2 0 0 2 2 2 1 Peptidase C1-like family Peptidase_C1 PF00112.18 KFM08813.1 - 3.6e-82 275.4 2.7 4.1e-82 275.2 1.9 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 KFM08813.1 - 5.2e-06 25.2 1.1 0.0028 16.2 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Inhibitor_I29 PF08246.7 KFM08813.1 - 0.0012 19.0 0.0 0.002 18.3 0.0 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1 PF00112.18 KFM08814.1 - 6e-82 274.7 2.4 7.1e-82 274.5 1.7 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 KFM08814.1 - 9.4e-08 32.2 0.0 1.6e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 KFM08814.1 - 2.8e-06 26.1 2.9 0.00049 18.7 0.5 2.1 2 0 0 2 2 2 2 Peptidase C1-like family PAS_11 PF14598.1 KFM08815.1 - 1.2e-24 86.3 0.6 1.2e-20 73.4 0.3 2.8 2 1 0 2 2 2 2 PAS domain PAS_3 PF08447.6 KFM08815.1 - 2.1e-23 82.2 0.0 2.2e-17 62.9 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS PF00989.19 KFM08815.1 - 4.4e-21 74.7 0.1 4.8e-13 48.8 0.0 2.9 3 0 0 3 3 3 2 PAS fold HLH PF00010.21 KFM08815.1 - 9.7e-15 54.0 1.2 3.1e-14 52.3 0.8 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.1 KFM08815.1 - 1e-08 35.4 0.0 3.1e-07 30.7 0.0 2.6 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 KFM08815.1 - 0.00072 19.5 0.0 0.75 9.8 0.0 2.9 3 0 0 3 3 3 2 PAS fold P4Ha_N PF08336.6 KFM08816.1 - 0.014 15.2 3.6 0.046 13.5 0.5 2.3 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region RmuC PF02646.11 KFM08816.1 - 0.097 11.4 10.3 0.049 12.4 3.1 2.0 1 1 1 2 2 2 0 RmuC family PYC_OADA PF02436.13 KFM08816.1 - 0.35 10.2 2.8 0.16 11.3 0.5 1.6 2 0 0 2 2 2 0 Conserved carboxylase domain Laminin_II PF06009.7 KFM08816.1 - 0.42 10.3 6.5 0.19 11.4 0.9 2.5 2 1 0 2 2 2 0 Laminin Domain II DOG1 PF14144.1 KFM08816.1 - 0.45 10.6 2.1 1.4 9.0 0.1 2.4 2 0 0 2 2 2 0 Seed dormancy control DUF948 PF06103.6 KFM08816.1 - 0.56 10.1 4.5 11 5.9 0.0 2.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) TMF_DNA_bd PF12329.3 KFM08816.1 - 1 9.1 13.9 0.15 11.9 1.7 3.1 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Alb1 PF09135.6 KFM08816.1 - 2.5 8.7 7.6 0.5 10.9 0.6 2.6 3 0 0 3 3 3 0 Alb1 AAA_13 PF13166.1 KFM08816.1 - 4.7 5.5 10.9 1.7 6.9 4.9 1.8 1 1 0 2 2 2 0 AAA domain BLOC1_2 PF10046.4 KFM08816.1 - 7 6.8 10.1 4.6 7.4 2.8 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATP-cone PF03477.11 KFM08816.1 - 8.7 6.8 8.9 2.6 8.5 3.2 2.5 2 1 0 2 2 2 0 ATP cone domain DUF544 PF04424.8 KFM08817.1 - 2e-31 108.3 0.0 2.7e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF544) PBD PF00786.23 KFM08818.1 - 0.00083 19.7 0.1 0.0014 19.0 0.1 1.3 1 0 0 1 1 1 1 P21-Rho-binding domain Ank_2 PF12796.2 KFM08819.1 - 1.1e-32 112.2 0.4 2.7e-21 75.7 0.4 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFM08819.1 - 1.4e-31 106.6 1.5 1.8e-10 40.1 0.1 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 KFM08819.1 - 9e-26 87.3 0.7 7.9e-08 31.8 0.1 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 KFM08819.1 - 1.7e-23 82.0 0.7 1.3e-07 31.5 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFM08819.1 - 3e-21 75.3 1.6 4e-10 39.9 0.3 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Tropomodulin PF03250.9 KFM08820.1 - 6.2e-13 48.5 0.0 1.3e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Tropomodulin LRR_6 PF13516.1 KFM08820.1 - 0.0079 16.1 2.0 0.03 14.3 0.1 2.7 3 0 0 3 3 3 1 Leucine Rich repeat LRR_4 PF12799.2 KFM08820.1 - 0.31 10.7 2.2 6.6 6.4 1.5 2.4 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) YL1 PF05764.8 KFM08821.1 - 2.8e-39 135.1 13.2 3.3e-39 134.9 9.1 1.1 1 0 0 1 1 1 1 YL1 nuclear protein PIP5K PF01504.13 KFM08822.1 - 6e-79 264.7 0.1 8.1e-79 264.2 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase UIM PF02809.15 KFM08823.1 - 3.5e-11 41.6 6.7 1.5e-05 24.1 0.7 3.3 2 0 0 2 2 2 2 Ubiquitin interaction motif VWA_2 PF13519.1 KFM08823.1 - 0.0014 18.7 1.7 0.017 15.2 0.0 2.7 2 1 0 3 3 3 1 von Willebrand factor type A domain PI3_PI4_kinase PF00454.22 KFM08824.1 - 3.2e-28 98.7 0.0 3.2e-27 95.5 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase RFX_DNA_binding PF02257.10 KFM08825.1 - 6.7e-33 112.6 0.1 8.3e-33 112.3 0.1 1.1 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.11 KFM08825.1 - 1.7e-05 25.0 0.0 2.7e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.6 KFM08825.1 - 0.099 12.3 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 CDC6, C terminal SBP56 PF05694.6 KFM08826.1 - 2.2e-212 705.5 0.0 2.6e-212 705.3 0.0 1.0 1 0 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.4 KFM08826.1 - 9.1e-05 21.6 0.0 0.00054 19.1 0.0 1.9 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller SBP56 PF05694.6 KFM08827.1 - 5.6e-126 420.7 0.0 6.3e-126 420.5 0.0 1.0 1 0 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.4 KFM08827.1 - 0.00041 19.5 0.0 0.0036 16.4 0.0 2.0 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller SBP56 PF05694.6 KFM08828.1 - 3e-160 533.7 0.0 3.3e-160 533.5 0.0 1.0 1 0 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.4 KFM08828.1 - 0.00044 19.4 0.0 0.0052 15.8 0.0 2.0 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller DUF1958 PF09211.5 KFM08828.1 - 0.16 12.0 0.1 0.31 11.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1958) SBP56 PF05694.6 KFM08829.1 - 1.3e-217 722.8 0.0 1.5e-217 722.6 0.0 1.0 1 0 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.4 KFM08829.1 - 0.00011 21.3 0.0 0.00079 18.6 0.0 2.0 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller zf-C2H2_4 PF13894.1 KFM08830.1 - 7.5e-06 25.9 59.8 0.0036 17.5 0.4 7.6 7 0 0 7 7 7 5 C2H2-type zinc finger zf-Di19 PF05605.7 KFM08830.1 - 1.8e-05 24.7 38.1 0.11 12.5 0.3 5.3 4 1 1 5 5 5 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 KFM08830.1 - 8.4e-05 22.6 62.1 0.13 12.6 0.5 7.7 7 1 0 7 7 7 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM08830.1 - 0.037 14.3 0.3 0.037 14.3 0.2 7.5 9 1 0 9 9 9 0 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFM08830.1 - 0.045 13.9 32.0 0.16 12.1 0.4 6.5 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding PyrI_C PF02748.10 KFM08830.1 - 0.062 12.7 0.1 0.062 12.7 0.1 4.1 4 1 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF2757 PF10955.3 KFM08830.1 - 0.32 11.2 6.8 0.42 10.8 2.3 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2757) Rubredoxin PF00301.15 KFM08830.1 - 0.41 10.5 19.2 1.2 9.0 0.0 6.1 6 1 0 6 6 6 0 Rubredoxin zinc_ribbon_4 PF13717.1 KFM08830.1 - 0.68 9.6 0.1 0.68 9.6 0.0 5.6 7 0 0 7 7 7 0 zinc-ribbon domain zf-C2H2_2 PF12756.2 KFM08830.1 - 8.4 6.5 38.4 3.6 7.7 0.8 5.9 2 1 3 5 5 5 0 C2H2 type zinc-finger (2 copies) Proteasome PF00227.21 KFM08831.1 - 3.2e-32 111.3 0.1 3.7e-32 111.1 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit GCOM2 PF15328.1 KFM08832.1 - 5.8e-08 32.7 3.8 7.1e-08 32.4 2.6 1.1 1 0 0 1 1 1 1 Putative GRINL1B complex locus protein 2 bZIP_1 PF00170.16 KFM08832.1 - 0.00049 19.9 15.3 0.0059 16.5 0.3 3.5 3 1 0 3 3 3 2 bZIP transcription factor SlyX PF04102.7 KFM08832.1 - 0.0098 16.2 17.4 0.097 13.0 4.2 3.1 2 1 1 3 3 3 1 SlyX Cast PF10174.4 KFM08832.1 - 0.025 12.6 14.8 0.038 12.0 10.3 1.4 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Reo_sigmaC PF04582.7 KFM08832.1 - 0.026 13.7 0.7 0.027 13.6 0.5 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein VirC1 PF07015.6 KFM08832.1 - 0.03 13.4 0.3 0.038 13.0 0.2 1.1 1 0 0 1 1 1 0 VirC1 protein Gp58 PF07902.6 KFM08832.1 - 0.033 12.3 2.3 0.038 12.2 1.6 1.0 1 0 0 1 1 1 0 gp58-like protein IDO PF01231.13 KFM08832.1 - 0.039 12.3 0.5 0.06 11.7 0.4 1.3 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase Herpes_env PF01673.13 KFM08832.1 - 0.046 12.2 0.5 0.1 11.1 0.0 1.7 1 1 1 2 2 2 0 Herpesvirus putative major envelope glycoprotein DUF2265 PF10023.4 KFM08832.1 - 0.051 12.7 2.2 0.063 12.4 1.5 1.1 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) Tropomyosin_1 PF12718.2 KFM08832.1 - 0.059 13.2 17.1 0.12 12.2 11.9 1.5 1 1 0 1 1 1 0 Tropomyosin like Prominin PF05478.6 KFM08832.1 - 0.063 10.8 1.8 0.067 10.7 1.2 1.1 1 0 0 1 1 1 0 Prominin DUF4200 PF13863.1 KFM08832.1 - 0.075 12.9 18.8 0.045 13.6 7.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) bZIP_2 PF07716.10 KFM08832.1 - 0.079 12.8 1.1 0.079 12.8 0.7 3.6 3 2 0 3 3 3 0 Basic region leucine zipper Spc7 PF08317.6 KFM08832.1 - 0.11 11.1 11.6 0.14 10.8 8.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DNA_primase_lrg PF04104.9 KFM08832.1 - 0.11 11.6 1.5 0.13 11.4 1.0 1.3 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit DUF342 PF03961.8 KFM08832.1 - 0.11 10.8 7.2 0.14 10.5 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) ADIP PF11559.3 KFM08832.1 - 0.12 12.3 15.6 1.3 8.8 8.9 2.6 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Jnk-SapK_ap_N PF09744.4 KFM08832.1 - 0.17 11.8 17.0 2 8.3 8.4 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 NYD-SP28 PF14772.1 KFM08832.1 - 0.2 11.7 12.5 14 5.8 8.6 2.4 1 1 0 1 1 1 0 Sperm tail V_ATPase_I PF01496.14 KFM08832.1 - 0.2 9.4 6.7 0.22 9.3 4.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_32 PF13654.1 KFM08832.1 - 0.2 10.2 7.7 0.24 9.9 5.3 1.1 1 0 0 1 1 1 0 AAA domain DUF2937 PF11157.3 KFM08832.1 - 0.2 10.9 6.0 0.14 11.5 2.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) LMBR1 PF04791.11 KFM08832.1 - 0.22 10.0 2.5 0.23 9.9 1.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein TMF_DNA_bd PF12329.3 KFM08832.1 - 0.24 11.2 18.7 1.9 8.3 1.1 3.1 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Hemerythrin PF01814.18 KFM08832.1 - 0.28 11.3 9.5 0.9 9.6 0.8 2.2 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain TBPIP PF07106.8 KFM08832.1 - 0.31 10.5 12.6 0.17 11.3 7.4 1.5 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fmp27_WPPW PF10359.4 KFM08832.1 - 0.32 9.3 7.1 0.38 9.1 4.9 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain COG2 PF06148.6 KFM08832.1 - 0.37 10.6 10.2 0.52 10.1 5.9 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 HAUS5 PF14817.1 KFM08832.1 - 0.44 9.0 12.5 0.42 9.0 8.0 1.3 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 5 IncA PF04156.9 KFM08832.1 - 0.51 9.9 18.5 0.34 10.4 8.8 1.8 1 1 0 1 1 1 0 IncA protein DUF1664 PF07889.7 KFM08832.1 - 0.52 10.1 7.3 0.67 9.7 4.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF445 PF04286.7 KFM08832.1 - 0.53 9.7 9.0 0.57 9.6 6.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Fib_alpha PF08702.5 KFM08832.1 - 0.63 10.1 10.0 9.2 6.3 3.9 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TMCO5 PF14992.1 KFM08832.1 - 0.65 9.0 13.6 1.7 7.7 9.4 1.5 1 1 0 1 1 1 0 TMCO5 family AAA_13 PF13166.1 KFM08832.1 - 0.68 8.3 6.1 0.73 8.2 4.2 1.1 1 0 0 1 1 1 0 AAA domain ATG16 PF08614.6 KFM08832.1 - 0.68 9.7 16.3 2.5 7.8 11.3 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) HalX PF08663.5 KFM08832.1 - 0.73 9.8 5.4 1.2 9.2 0.7 2.6 1 1 1 2 2 2 0 HalX domain CCDC-167 PF15188.1 KFM08832.1 - 0.73 9.8 14.4 0.54 10.2 2.6 2.7 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 167 TMPIT PF07851.8 KFM08832.1 - 1 8.3 4.6 1.3 8.0 3.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF3450 PF11932.3 KFM08832.1 - 1.1 8.5 10.5 1.6 7.8 6.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) CorA PF01544.13 KFM08832.1 - 1.1 8.2 6.1 1.3 7.9 4.3 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein NPV_P10 PF05531.7 KFM08832.1 - 1.3 9.2 4.8 1.9 8.8 2.1 2.0 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TSC22 PF01166.13 KFM08832.1 - 1.4 8.9 8.4 6.5 6.8 0.1 3.3 1 1 3 4 4 4 0 TSC-22/dip/bun family DUF4618 PF15397.1 KFM08832.1 - 1.4 8.1 14.6 5.4 6.2 7.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Med9 PF07544.8 KFM08832.1 - 1.5 8.6 11.4 1.5 8.5 5.8 2.5 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Allexi_40kDa PF05549.6 KFM08832.1 - 1.5 8.0 4.8 2.3 7.4 3.2 1.4 1 1 0 1 1 1 0 Allexivirus 40kDa protein CENP-F_leu_zip PF10473.4 KFM08832.1 - 1.6 8.5 19.5 0.14 12.0 7.0 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin_2 PF01920.15 KFM08832.1 - 1.9 8.2 16.9 2.7 7.7 0.7 3.1 1 1 2 3 3 3 0 Prefoldin subunit Sec2p PF06428.6 KFM08832.1 - 2 8.2 14.1 5.9 6.8 6.2 2.9 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p DUF972 PF06156.8 KFM08832.1 - 2.1 8.7 13.9 1 9.7 2.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Seryl_tRNA_N PF02403.17 KFM08832.1 - 2.3 8.2 13.2 2.2 8.3 6.8 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain KSR1-SAM PF13543.1 KFM08832.1 - 3.1 7.5 8.8 2.3 8.0 1.0 2.7 2 1 1 3 3 3 0 SAM like domain present in kinase suppressor RAS 1 ACCA PF03255.9 KFM08832.1 - 3.2 7.3 8.4 1.7 8.2 3.8 2.0 2 1 0 2 2 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Syntaxin PF00804.20 KFM08832.1 - 3.5 7.8 10.8 9.6 6.4 7.5 1.9 1 1 0 1 1 1 0 Syntaxin MRP-S26 PF14943.1 KFM08832.1 - 3.9 7.0 14.8 1.6 8.2 5.7 2.1 1 1 1 2 2 2 0 Mitochondrial ribosome subunit S26 APG6 PF04111.7 KFM08832.1 - 4.6 6.1 11.6 6.5 5.7 8.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 COG5 PF10392.4 KFM08832.1 - 5.1 7.0 9.1 6.4 6.7 5.9 1.5 1 1 0 1 1 1 0 Golgi transport complex subunit 5 KLRAQ PF10205.4 KFM08832.1 - 5.2 7.1 12.0 2.5 8.1 4.3 2.1 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein HemX PF04375.9 KFM08832.1 - 5.6 5.4 11.1 4 5.9 6.0 1.7 1 1 1 2 2 2 0 HemX CENP-Q PF13094.1 KFM08832.1 - 6.1 6.8 17.4 0.96 9.4 7.8 2.3 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF641 PF04859.7 KFM08832.1 - 6.4 6.5 13.1 8.6 6.1 4.7 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Mnd1 PF03962.10 KFM08832.1 - 8.1 6.0 13.8 30 4.2 8.5 1.9 1 1 1 2 2 2 0 Mnd1 family GrpE PF01025.14 KFM08832.1 - 8.5 5.8 13.1 26 4.2 2.6 2.6 1 1 1 2 2 2 0 GrpE PX PF00787.19 KFM08833.1 - 1.4e-19 69.9 0.1 3.1e-19 68.8 0.1 1.5 1 0 0 1 1 1 1 PX domain RA PF00788.18 KFM08833.1 - 7.7e-12 45.5 0.1 3e-11 43.6 0.0 2.1 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain USP7_C2 PF14533.1 KFM08833.1 - 0.0076 15.7 0.1 0.012 15.0 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal FERM_N PF09379.5 KFM08833.1 - 0.028 14.4 0.1 0.089 12.8 0.0 2.1 1 1 0 1 1 1 0 FERM N-terminal domain DED PF01335.16 KFM08834.1 - 4.6e-18 65.1 0.2 8.9e-18 64.2 0.1 1.5 1 0 0 1 1 1 1 Death effector domain IRK PF01007.15 KFM08835.1 - 1.1e-145 484.6 0.1 1.3e-145 484.4 0.1 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 KFM08835.1 - 0.021 14.5 3.7 0.049 13.3 2.5 1.7 1 1 0 1 1 1 0 Ion channel IRK PF01007.15 KFM08836.1 - 3.8e-140 466.4 0.3 4.2e-140 466.3 0.2 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 KFM08836.1 - 0.00053 19.6 7.1 0.0019 17.8 4.9 2.0 1 1 0 1 1 1 1 Ion channel DUF3938 PF13074.1 KFM08836.1 - 0.97 9.3 3.4 0.71 9.7 1.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) DED PF01335.16 KFM08837.1 - 6.6e-20 71.0 0.2 8.3e-20 70.7 0.2 1.1 1 0 0 1 1 1 1 Death effector domain FCD PF07729.7 KFM08837.1 - 0.0039 17.4 0.5 0.0073 16.6 0.3 1.4 1 1 0 1 1 1 1 FCD domain DUF1281 PF06924.6 KFM08837.1 - 0.069 12.5 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) DUF2247 PF10004.4 KFM08837.1 - 0.084 12.5 0.5 0.097 12.3 0.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) DUF4381 PF14316.1 KFM08837.1 - 0.14 12.2 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) WD40 PF00400.27 KFM08838.1 - 0.002 17.9 0.1 0.19 11.7 0.0 3.0 2 1 0 2 2 2 1 WD domain, G-beta repeat Birna_VP3 PF01767.11 KFM08838.1 - 0.038 13.6 1.3 0.058 13.0 0.9 1.2 1 0 0 1 1 1 0 Birnavirus VP3 protein DUF4661 PF15576.1 KFM08838.1 - 0.26 10.8 5.7 0.39 10.3 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) DUF1510 PF07423.6 KFM08838.1 - 3.3 7.0 15.9 4.7 6.5 11.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 KFM08838.1 - 7 4.5 16.7 9.4 4.1 11.6 1.1 1 0 0 1 1 1 0 CDC45-like protein eIF-3c_N PF05470.7 KFM08838.1 - 8.3 4.3 10.7 11 3.9 7.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SDA1 PF05285.7 KFM08838.1 - 8.8 5.5 22.4 11 5.1 15.5 1.1 1 0 0 1 1 1 0 SDA1 Glyco_transf_7N PF13733.1 KFM08840.1 - 2.6e-53 179.0 0.1 3.3e-53 178.7 0.1 1.1 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.9 KFM08840.1 - 5.4e-31 105.8 0.0 9.1e-31 105.1 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFM08840.1 - 1.1e-09 37.8 0.0 0.00018 20.6 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase like family 2 IQ PF00612.22 KFM08841.1 - 0.044 13.4 0.3 0.049 13.2 0.2 1.1 1 0 0 1 1 1 0 IQ calmodulin-binding motif Ca_chan_IQ PF08763.6 KFM08841.1 - 0.053 12.7 1.1 0.068 12.4 0.8 1.2 1 0 0 1 1 1 0 Voltage gated calcium channel IQ domain Trichoplein PF13868.1 KFM08842.1 - 1.8e-66 223.9 159.4 1.8e-66 223.9 110.5 1.5 1 1 0 1 1 1 1 Tumour suppressor, Mitostatin CH PF00307.26 KFM08843.1 - 2.8e-14 53.0 0.0 3.3e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.6 KFM08843.1 - 0.0074 16.3 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 CDC24 Calponin CAMSAP_CH PF11971.3 KFM08843.1 - 0.085 12.5 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 CAMSAP CH domain I-set PF07679.11 KFM08844.1 - 3e-43 145.5 0.0 2.6e-12 46.4 0.0 6.0 6 0 0 6 6 6 5 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM08844.1 - 5.6e-40 135.3 1.8 7.8e-10 38.7 0.1 5.5 5 0 0 5 5 5 4 Immunoglobulin domain Ig_3 PF13927.1 KFM08844.1 - 2.2e-32 111.3 3.5 8.5e-08 32.5 0.1 5.8 5 0 0 5 5 5 4 Immunoglobulin domain ig PF00047.20 KFM08844.1 - 5.1e-26 90.5 0.1 1.6e-08 34.4 0.0 5.7 5 0 0 5 5 5 4 Immunoglobulin domain fn3 PF00041.16 KFM08844.1 - 2.3e-21 75.7 0.0 6e-10 39.1 0.0 3.0 2 0 0 2 2 2 2 Fibronectin type III domain V-set PF07686.12 KFM08844.1 - 1.5e-18 66.7 0.2 0.00025 20.9 0.0 6.5 6 2 0 6 6 6 3 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM08844.1 - 1.2e-06 28.3 0.7 0.58 10.0 0.0 3.7 3 0 0 3 3 3 3 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.11 KFM08844.1 - 0.004 15.4 0.2 0.25 9.5 0.0 3.0 3 0 0 3 3 3 1 Alphaherpesvirus glycoprotein E C2-set PF05790.10 KFM08844.1 - 0.017 15.1 0.1 0.73 9.8 0.0 3.1 3 0 0 3 3 3 0 Immunoglobulin C2-set domain V-set_CD47 PF08204.6 KFM08844.1 - 0.024 14.3 0.2 3.8 7.2 0.0 3.7 5 0 0 5 5 5 0 CD47 immunoglobulin-like domain Pentaxin PF00354.12 KFM08845.1 - 2.7e-76 255.3 0.0 3.1e-76 255.1 0.0 1.0 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.1 KFM08845.1 - 7.4e-10 39.2 0.0 9.5e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Ig_2 PF13895.1 KFM08846.1 - 2.7e-21 75.4 0.4 4.5e-10 39.4 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.11 KFM08846.1 - 8.8e-19 67.1 0.2 6.9e-08 32.2 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin I-set domain C2-set_2 PF08205.7 KFM08846.1 - 4e-18 65.1 2.3 7.1e-18 64.2 0.2 2.4 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.1 KFM08846.1 - 1e-17 64.3 0.2 7.6e-06 26.3 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.20 KFM08846.1 - 6.4e-17 61.4 1.1 5e-06 26.5 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 KFM08846.1 - 2.2e-09 37.2 4.1 0.0012 18.6 0.0 4.3 1 1 1 3 3 3 2 Immunoglobulin V-set domain C1-set PF07654.10 KFM08846.1 - 2.1e-08 34.0 0.4 7.2e-08 32.3 0.1 2.0 2 0 0 2 2 2 1 Immunoglobulin C1-set domain C2-set PF05790.10 KFM08846.1 - 0.0095 15.8 3.1 2.7 8.0 0.5 3.1 3 1 0 3 3 3 2 Immunoglobulin C2-set domain C1-set PF07654.10 KFM08847.1 - 7.1e-16 57.9 0.0 8.9e-16 57.6 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin C1-set domain ig PF00047.20 KFM08847.1 - 0.0095 16.0 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFM08847.1 - 0.018 15.5 0.0 0.025 15.0 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain C2-set_2 PF08205.7 KFM08847.1 - 0.027 14.3 0.0 0.036 13.9 0.0 1.1 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.1 KFM08847.1 - 0.041 13.9 0.0 0.047 13.8 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain C1-set PF07654.10 KFM08848.1 - 4.9e-16 58.5 0.0 6.3e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin C1-set domain ig PF00047.20 KFM08848.1 - 0.0095 16.0 0.0 0.014 15.5 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFM08848.1 - 0.018 15.5 0.1 0.025 15.1 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain C2-set_2 PF08205.7 KFM08848.1 - 0.032 14.1 0.0 0.04 13.8 0.0 1.1 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.1 KFM08848.1 - 0.041 13.9 0.0 0.047 13.8 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain Pkinase_Tyr PF07714.12 KFM08849.1 - 2e-94 315.5 0.0 2.7e-94 315.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ephrin_lbd PF01404.14 KFM08849.1 - 2.5e-75 252.1 0.1 3.7e-75 251.6 0.1 1.3 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase PF00069.20 KFM08849.1 - 1.2e-46 158.9 0.0 1.8e-46 158.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.16 KFM08849.1 - 1.7e-26 92.1 0.1 6.7e-16 58.1 0.1 3.0 3 0 0 3 3 3 2 Fibronectin type III domain SAM_2 PF07647.12 KFM08849.1 - 2.6e-20 72.0 0.0 4.9e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EphA2_TM PF14575.1 KFM08849.1 - 3.6e-20 72.1 0.0 6.5e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SAM_1 PF00536.25 KFM08849.1 - 2.1e-19 69.4 0.1 4.2e-19 68.4 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) GCC2_GCC3 PF07699.8 KFM08849.1 - 1.8e-05 24.1 0.5 1.8e-05 24.1 0.3 2.4 2 0 0 2 2 2 1 GCC2 and GCC3 Y_Y_Y PF07495.8 KFM08849.1 - 0.013 15.2 0.1 0.051 13.3 0.0 1.9 2 0 0 2 2 2 0 Y_Y_Y domain Interfer-bind PF09294.5 KFM08849.1 - 0.019 14.9 0.0 0.22 11.5 0.0 2.6 3 0 0 3 3 3 0 Interferon-alpha/beta receptor, fibronectin type III Kdo PF06293.9 KFM08849.1 - 0.12 11.3 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family cEGF PF12662.2 KFM08849.1 - 0.55 9.9 8.3 0.022 14.4 1.0 2.3 2 0 0 2 2 2 0 Complement Clr-like EGF-like Ank_2 PF12796.2 KFM08850.1 - 8.6e-26 90.1 3.4 5.3e-14 52.3 1.0 3.1 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFM08850.1 - 1.7e-20 71.6 1.5 1.6e-05 24.4 0.0 5.7 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 KFM08850.1 - 1.2e-19 70.2 0.1 2.9e-05 24.4 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM08850.1 - 1.9e-19 67.8 2.6 2.5e-05 24.0 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 KFM08850.1 - 4.3e-18 64.9 3.0 0.00014 21.9 0.0 5.1 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ion_trans PF00520.26 KFM08850.1 - 3.1e-12 46.1 22.7 3.1e-12 46.1 15.7 2.0 2 0 0 2 2 2 1 Ion transport protein OKR_DC_1 PF01276.15 KFM08850.1 - 0.084 11.4 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain SRCR PF00530.13 KFM08851.1 - 7.6e-107 350.1 49.9 3.8e-33 113.7 4.8 5.0 5 0 0 5 5 5 5 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 KFM08851.1 - 3.8e-13 49.5 12.5 0.00084 19.5 0.2 4.6 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain Syntaxin PF00804.20 KFM08852.1 - 1.2e-14 54.2 1.9 1.9e-14 53.6 1.3 1.3 1 0 0 1 1 1 1 Syntaxin Syntaxin_2 PF14523.1 KFM08852.1 - 0.007 16.3 1.8 0.0079 16.2 1.2 1.1 1 0 0 1 1 1 1 Syntaxin-like protein Branch PF02485.16 KFM08852.1 - 0.068 12.3 0.2 0.074 12.1 0.1 1.0 1 0 0 1 1 1 0 Core-2/I-Branching enzyme DUF111 PF01969.12 KFM08852.1 - 0.068 11.9 0.4 0.067 11.9 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF111 Fra10Ac1 PF09725.4 KFM08852.1 - 0.13 12.3 0.4 0.15 12.1 0.3 1.1 1 0 0 1 1 1 0 Folate-sensitive fragile site protein Fra10Ac1 Ldl_recept_a PF00057.13 KFM08853.1 - 6.6e-106 345.9 216.4 2.4e-14 52.9 5.1 12.3 12 1 1 13 13 13 11 Low-density lipoprotein receptor domain class A fn3 PF00041.16 KFM08853.1 - 6e-33 112.8 15.7 6.6e-09 35.7 0.2 6.5 6 0 0 6 6 6 5 Fibronectin type III domain Ldl_recept_b PF00058.12 KFM08853.1 - 2.2e-24 85.5 6.3 1.4e-07 31.6 0.1 5.8 5 0 0 5 5 5 5 Low-density lipoprotein receptor repeat class B BNR PF02012.15 KFM08853.1 - 0.00023 20.5 13.3 2.2 8.4 0.2 5.7 5 0 0 5 5 5 2 BNR/Asp-box repeat DUF3377 PF11857.3 KFM08853.1 - 0.039 13.5 0.0 0.09 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) His_Phos_1 PF00300.17 KFM08854.1 - 1.5e-23 83.5 0.0 4.3e-23 82.1 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) SH3_9 PF14604.1 KFM08854.1 - 4.6e-17 61.3 0.1 1.4e-16 59.8 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain 2_5_RNA_ligase2 PF13563.1 KFM08854.1 - 1e-06 28.5 0.8 2.2e-06 27.4 0.2 1.7 2 0 0 2 2 2 1 2'-5' RNA ligase superfamily SH3_1 PF00018.23 KFM08854.1 - 3.9e-05 22.9 0.0 8.2e-05 21.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain LigT_PEase PF02834.11 KFM08854.1 - 4.8e-05 23.2 0.1 0.3 11.0 0.1 2.7 3 0 0 3 3 3 2 LigT like Phosphoesterase His_Phos_2 PF00328.17 KFM08854.1 - 0.029 13.7 0.0 0.06 12.6 0.0 1.5 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) DUF4591 PF15261.1 KFM08855.1 - 3.5e-40 137.3 8.7 3.5e-40 137.3 6.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4591) HSP70 PF00012.15 KFM08856.1 - 1e-277 921.9 12.4 1.2e-277 921.7 8.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFM08856.1 - 1.2e-18 66.8 0.5 3.3e-17 62.1 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 KFM08856.1 - 0.00036 20.3 3.0 0.12 12.2 0.1 3.5 2 2 0 2 2 2 2 Cell division protein FtsA FGGY_C PF02782.11 KFM08856.1 - 0.0014 18.3 0.0 0.0029 17.2 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 KFM08856.1 - 0.0063 15.3 0.4 0.046 12.5 0.1 2.1 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain BcrAD_BadFG PF01869.15 KFM08856.1 - 0.012 14.8 0.1 4.4 6.5 0.0 2.5 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.6 KFM08856.1 - 0.026 13.4 0.9 0.12 11.3 0.0 2.3 3 0 0 3 3 3 0 StbA protein Hydantoinase_A PF01968.13 KFM08856.1 - 0.033 13.2 1.1 0.45 9.5 0.1 2.7 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase V-set PF07686.12 KFM08857.1 - 1.6e-17 63.4 1.2 3e-12 46.4 0.0 2.7 2 1 1 3 3 3 2 Immunoglobulin V-set domain I-set PF07679.11 KFM08857.1 - 7e-16 57.8 0.0 1.4e-06 28.0 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM08857.1 - 3.6e-11 43.0 0.9 2.3e-06 27.6 0.2 2.5 1 1 1 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 KFM08857.1 - 1.5e-09 38.1 0.0 7.9e-05 23.0 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 KFM08857.1 - 2e-05 24.6 0.0 0.1 12.7 0.0 3.7 2 2 0 2 2 2 2 Immunoglobulin domain Herpes_gE PF02480.11 KFM08857.1 - 0.00055 18.3 0.4 3.5 5.7 0.1 3.0 1 1 1 3 3 3 3 Alphaherpesvirus glycoprotein E TMEM51 PF15345.1 KFM08857.1 - 0.0062 16.2 1.0 0.011 15.4 0.7 1.4 1 0 0 1 1 1 1 Transmembrane protein 51 Glycophorin_A PF01102.13 KFM08857.1 - 0.015 15.0 4.2 0.15 11.8 0.0 2.4 2 0 0 2 2 2 0 Glycophorin A FAM176 PF14851.1 KFM08857.1 - 0.037 13.7 0.1 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 FAM176 family DUF1191 PF06697.7 KFM08857.1 - 0.038 12.8 0.5 0.11 11.3 0.2 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1191) DUF2531 PF10748.4 KFM08857.1 - 0.065 12.4 0.1 0.74 9.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2531) SR-25 PF10500.4 KFM08857.1 - 0.078 12.4 9.6 0.12 11.7 6.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Sp38 PF07354.7 KFM08857.1 - 0.091 11.3 0.0 0.16 10.6 0.0 1.3 1 0 0 1 1 1 0 Zona-pellucida-binding protein (Sp38) DUF2051 PF09738.4 KFM08857.1 - 4.7 6.3 6.3 8.2 5.6 4.4 1.3 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) GRAM PF02893.15 KFM08858.1 - 1.4e-19 69.3 0.1 2.8e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 GRAM domain V-set PF07686.12 KFM08859.1 - 8.2e-16 57.9 0.1 1e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 KFM08859.1 - 0.00012 22.1 0.8 0.00036 20.5 0.5 1.8 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 KFM08859.1 - 0.00054 19.7 0.1 0.001 18.8 0.1 1.6 1 1 0 1 1 1 1 Immunoglobulin I-set domain Herpes_gE PF02480.11 KFM08859.1 - 0.00078 17.8 0.3 0.24 9.6 0.0 2.2 1 1 1 2 2 2 2 Alphaherpesvirus glycoprotein E Ig_2 PF13895.1 KFM08859.1 - 0.0022 18.0 0.1 0.0053 16.8 0.1 1.7 1 1 0 1 1 1 1 Immunoglobulin domain EII-GUT PF03608.8 KFM08859.1 - 0.019 14.7 0.1 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 PTS system enzyme II sorbitol-specific factor Ig_3 PF13927.1 KFM08859.1 - 0.034 14.6 0.7 0.2 12.1 0.5 2.1 1 1 0 1 1 1 0 Immunoglobulin domain OAD_gamma PF04277.8 KFM08859.1 - 0.04 14.2 0.0 0.072 13.4 0.0 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF843 PF05814.6 KFM08859.1 - 0.045 13.5 0.2 0.091 12.5 0.2 1.5 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) E1-E2_ATPase PF00122.15 KFM08860.1 - 3e-59 199.8 3.9 6.9e-59 198.6 2.7 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFM08860.1 - 2.6e-42 144.4 1.9 2.6e-42 144.4 1.3 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFM08860.1 - 5.9e-30 105.2 0.0 1.8e-29 103.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFM08860.1 - 2.5e-26 91.4 0.0 5.2e-26 90.4 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KFM08860.1 - 5.7e-17 62.5 0.0 1.3e-16 61.3 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFM08860.1 - 3e-16 58.6 0.0 6.3e-16 57.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KFM08860.1 - 9.1e-07 28.6 2.3 0.00041 20.0 0.8 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Sigma70_r4 PF04545.11 KFM08860.1 - 0.013 14.7 0.1 0.033 13.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 Cytidylate_kin2 PF13189.1 KFM08860.1 - 0.051 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase-like family Glyco_transf_43 PF03360.11 KFM08861.1 - 3.2e-82 275.0 0.0 3.7e-82 274.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 43 Acyl-CoA_dh_1 PF00441.19 KFM08862.1 - 3.8e-46 156.8 5.3 5.4e-46 156.3 3.6 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KFM08862.1 - 1.6e-28 99.4 0.1 4.7e-28 98.0 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KFM08862.1 - 3.6e-22 79.0 2.6 5.5e-22 78.4 1.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KFM08862.1 - 3.5e-21 74.4 0.1 8.6e-21 73.2 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 KFM08862.1 - 0.076 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal EVE PF01878.13 KFM08863.1 - 1.6e-51 174.0 0.1 1.6e-51 174.0 0.0 1.4 2 0 0 2 2 2 1 EVE domain Vps26 PF03643.10 KFM08864.1 - 4.6e-123 409.3 3.7 5.5e-123 409.1 2.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 KFM08864.1 - 0.00051 19.8 1.2 0.94 9.2 0.0 3.5 4 0 0 4 4 4 2 Arrestin (or S-antigen), N-terminal domain I-set PF07679.11 KFM08865.1 - 3.6e-20 71.6 0.7 7.8e-11 41.6 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.12 KFM08865.1 - 3.9e-18 65.4 3.3 1.5e-09 37.7 0.1 2.3 1 1 1 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.1 KFM08865.1 - 1.7e-16 60.0 3.2 4.8e-09 36.2 0.4 2.2 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 KFM08865.1 - 1.9e-11 43.8 8.5 6.2e-05 23.0 0.5 3.8 2 2 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 KFM08865.1 - 5.4e-08 33.2 9.3 3.9e-06 27.2 2.2 3.0 2 2 0 2 2 2 2 Immunoglobulin domain C1-set PF07654.10 KFM08865.1 - 1.2e-06 28.3 1.2 0.008 16.1 0.1 2.4 2 0 0 2 2 2 2 Immunoglobulin C1-set domain C2-set_2 PF08205.7 KFM08865.1 - 0.00014 21.6 0.7 0.0085 15.9 0.1 2.4 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain EphA2_TM PF14575.1 KFM08865.1 - 0.1 13.0 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.10 KFM08865.1 - 0.14 11.7 4.6 0.26 10.8 3.2 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 I-set PF07679.11 KFM08866.1 - 1.8e-41 139.8 0.0 7.8e-09 35.2 0.0 5.7 6 0 0 6 6 6 5 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM08866.1 - 2.8e-32 110.6 0.0 2e-07 31.0 0.0 5.3 5 0 0 5 5 5 5 Immunoglobulin domain Ig_3 PF13927.1 KFM08866.1 - 4.1e-23 81.6 3.0 7.2e-08 32.8 0.0 6.6 6 1 0 6 6 6 5 Immunoglobulin domain V-set PF07686.12 KFM08866.1 - 8.9e-20 70.6 0.0 9.7e-07 28.6 0.0 5.3 5 0 0 5 5 5 3 Immunoglobulin V-set domain ig PF00047.20 KFM08866.1 - 8e-18 64.3 0.0 0.0026 17.8 0.0 5.7 5 0 0 5 5 5 4 Immunoglobulin domain fn3 PF00041.16 KFM08866.1 - 6.6e-15 55.0 0.0 2.6e-06 27.4 0.0 3.0 3 0 0 3 3 3 2 Fibronectin type III domain Tissue_fac PF01108.12 KFM08866.1 - 0.0046 16.6 0.1 0.1 12.3 0.1 2.4 2 0 0 2 2 2 1 Tissue factor Herpes_gE PF02480.11 KFM08866.1 - 0.012 13.9 0.0 18 3.4 0.0 3.9 4 1 0 4 4 4 0 Alphaherpesvirus glycoprotein E Ldr_toxin PF13940.1 KFM08866.1 - 0.055 13.2 0.7 6.2 6.6 0.3 2.9 1 1 1 2 2 2 0 Toxin Ldr, type I toxin-antitoxin system V-set_CD47 PF08204.6 KFM08866.1 - 0.097 12.4 0.0 27 4.5 0.0 3.7 4 0 0 4 4 4 0 CD47 immunoglobulin-like domain I-set PF07679.11 KFM08868.1 - 6.5e-37 125.2 2.7 4.8e-15 55.1 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM08868.1 - 7.9e-29 99.6 1.6 3.6e-11 43.0 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 KFM08868.1 - 2.8e-24 85.3 5.8 5.9e-11 42.7 0.0 3.3 3 1 0 3 3 3 3 Immunoglobulin domain ig PF00047.20 KFM08868.1 - 1e-21 76.8 2.1 4.1e-10 39.6 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 KFM08868.1 - 7.1e-16 58.1 7.1 4.5e-05 23.3 0.3 4.7 3 2 0 3 3 3 3 Immunoglobulin V-set domain V-set_CD47 PF08204.6 KFM08868.1 - 0.00014 21.6 0.8 0.29 10.9 0.1 3.1 3 0 0 3 3 3 2 CD47 immunoglobulin-like domain C2-set_2 PF08205.7 KFM08868.1 - 0.0015 18.4 0.3 0.43 10.5 0.0 2.7 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.11 KFM08868.1 - 0.003 15.9 0.7 0.018 13.3 0.2 2.3 1 1 1 2 2 2 1 Alphaherpesvirus glycoprotein E I-set PF07679.11 KFM08869.1 - 1.7e-29 101.5 1.2 1e-11 44.5 0.1 3.6 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM08869.1 - 4.4e-20 71.5 0.9 1e-09 38.3 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 KFM08869.1 - 1.6e-19 70.1 5.8 5.3e-11 42.8 0.1 3.6 4 1 0 4 4 4 2 Immunoglobulin domain V-set PF07686.12 KFM08869.1 - 6.5e-14 51.8 0.9 0.001 18.9 0.1 4.2 3 1 0 3 3 3 3 Immunoglobulin V-set domain ig PF00047.20 KFM08869.1 - 9.7e-14 51.2 4.9 0.00015 21.8 0.2 4.4 3 2 0 3 3 3 3 Immunoglobulin domain Herpes_gE PF02480.11 KFM08869.1 - 0.00088 17.6 0.3 0.12 10.6 0.0 2.9 1 1 1 3 3 3 1 Alphaherpesvirus glycoprotein E V-set_CD47 PF08204.6 KFM08869.1 - 0.0022 17.7 0.7 1.2 8.9 0.1 3.0 3 0 0 3 3 3 2 CD47 immunoglobulin-like domain C2-set_2 PF08205.7 KFM08869.1 - 0.009 15.8 0.5 0.066 13.1 0.0 2.5 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain C2-set PF05790.10 KFM08869.1 - 0.09 12.7 0.2 72 3.4 0.0 3.5 3 1 1 4 4 4 0 Immunoglobulin C2-set domain Phage_XkdX PF09693.5 KFM08869.1 - 0.14 11.6 0.3 0.49 9.9 0.0 2.0 2 0 0 2 2 2 0 Phage uncharacterised protein (Phage_XkdX) Malic_M PF03949.10 KFM08870.1 - 8.4e-95 317.1 0.5 1.1e-94 316.8 0.3 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KFM08870.1 - 2.7e-81 271.4 0.0 4.1e-81 270.9 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain RE_BstXI PF09552.5 KFM08870.1 - 0.1 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 BstXI restriction endonuclease Peptidase_S28 PF05577.7 KFM08871.1 - 2.1e-99 333.0 0.0 2.4e-99 332.8 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 KFM08871.1 - 7e-06 26.0 0.0 1.1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFM08871.1 - 1.2e-05 24.9 0.0 1.8e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFM08871.1 - 0.00036 20.3 0.1 0.0013 18.5 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S37 PF05576.6 KFM08871.1 - 0.001 17.6 0.1 0.0053 15.2 0.0 2.1 1 1 1 2 2 2 1 PS-10 peptidase S37 Peptidase_S9 PF00326.16 KFM08871.1 - 0.0017 17.6 0.0 0.0038 16.4 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2920 PF11144.3 KFM08871.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Rep_fac-A_C PF08646.5 KFM08872.1 - 3e-10 39.9 0.2 5.5e-10 39.1 0.2 1.4 1 0 0 1 1 1 1 Replication factor-A C terminal domain Ras PF00071.17 KFM08874.1 - 1.6e-58 196.6 0.0 1.9e-58 196.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM08874.1 - 1.5e-20 73.8 0.0 2.3e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM08874.1 - 3.1e-15 55.8 0.0 4e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFM08874.1 - 6.2e-10 38.6 0.0 7.5e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFM08874.1 - 5.6e-06 25.9 0.0 8e-05 22.1 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFM08874.1 - 2.4e-05 24.2 0.0 4.6e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KFM08874.1 - 3.1e-05 23.6 0.8 0.0065 16.0 0.1 2.3 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein AAA PF00004.24 KFM08874.1 - 0.00022 21.4 0.0 0.0012 19.0 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.13 KFM08874.1 - 0.00053 19.3 0.5 0.0044 16.3 0.3 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 KFM08874.1 - 0.00075 18.7 0.0 0.001 18.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_5 PF07728.9 KFM08874.1 - 0.0026 17.4 0.1 0.0068 16.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 KFM08874.1 - 0.0027 17.2 0.2 0.016 14.7 0.1 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 KFM08874.1 - 0.0027 17.8 0.2 0.0068 16.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 KFM08874.1 - 0.013 15.1 0.1 0.028 14.0 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 KFM08874.1 - 0.022 14.7 0.2 0.037 14.0 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain cobW PF02492.14 KFM08874.1 - 0.049 13.0 0.3 4.8 6.5 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 KFM08874.1 - 0.051 13.2 0.7 0.16 11.5 0.0 2.0 2 1 1 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 KFM08874.1 - 0.065 13.5 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.16 KFM08874.1 - 0.078 12.1 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF258 PF03193.11 KFM08874.1 - 0.096 11.8 0.0 0.25 10.5 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 KFM08874.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KFM08874.1 - 0.16 11.9 0.7 1.2 9.0 0.1 2.1 2 0 0 2 2 2 0 AAA domain CTD_bind PF04818.8 KFM08875.1 - 8.6e-06 25.9 0.1 2.5e-05 24.4 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Ank_2 PF12796.2 KFM08876.1 - 2.4e-49 165.6 17.2 3.7e-16 59.2 1.7 4.2 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFM08876.1 - 7.7e-39 131.3 15.5 1.4e-09 38.2 0.3 7.3 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.25 KFM08876.1 - 9.5e-37 123.0 23.6 4.7e-07 29.3 0.6 8.3 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.1 KFM08876.1 - 3.2e-31 106.6 20.0 2.1e-09 37.3 0.0 7.1 2 2 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM08876.1 - 1.1e-20 71.6 15.5 3.1e-05 23.7 0.4 7.6 8 0 0 8 8 8 6 Ankyrin repeat Vps51 PF08700.6 KFM08876.1 - 0.047 13.5 3.1 0.15 11.9 2.2 1.9 1 0 0 1 1 1 0 Vps51/Vps67 DUF1640 PF07798.6 KFM08877.1 - 8.1e-69 231.1 11.9 9.5e-69 230.9 8.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Vac_Fusion PF02346.11 KFM08877.1 - 0.013 14.9 3.3 0.052 12.9 0.1 3.1 2 2 1 3 3 3 0 Chordopoxvirus fusion protein DUF3509 PF12021.3 KFM08877.1 - 0.041 13.6 2.9 0.2 11.4 2.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3509) MHC_I_2 PF14586.1 KFM08877.1 - 0.041 13.4 0.2 0.051 13.1 0.1 1.2 1 0 0 1 1 1 0 Class I Histocompatibility antigen, NKG2D ligand, domains 1 and 2 HALZ PF02183.13 KFM08877.1 - 0.043 13.5 1.5 0.073 12.8 0.3 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF972 PF06156.8 KFM08877.1 - 2.9 8.2 11.3 1.5 9.2 2.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) CemA PF03040.9 KFM08877.1 - 3.6 7.1 9.7 9.5 5.7 0.0 2.9 1 1 2 3 3 3 0 CemA family FlaC_arch PF05377.6 KFM08877.1 - 3.8 7.4 6.6 3.1 7.7 1.2 2.9 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF2175 PF09943.4 KFM08877.1 - 6.6 6.8 9.2 2.6 8.1 2.1 2.4 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) PDZ PF00595.19 KFM08878.1 - 7e-66 218.4 8.1 1.2e-21 76.6 0.1 3.4 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) Guanylate_kin PF00625.16 KFM08878.1 - 5.5e-64 214.9 0.1 9.1e-64 214.2 0.1 1.3 1 0 0 1 1 1 1 Guanylate kinase PDZ_assoc PF10600.4 KFM08878.1 - 5.2e-31 106.7 6.1 1e-30 105.8 4.2 1.5 1 0 0 1 1 1 1 PDZ-associated domain of NMDA receptors PDZ_2 PF13180.1 KFM08878.1 - 6.9e-18 64.3 3.8 5.5e-05 22.9 0.0 4.0 4 0 0 4 4 4 3 PDZ domain MAGUK_N_PEST PF10608.4 KFM08878.1 - 1.1e-11 45.0 0.2 3.5e-11 43.3 0.2 2.0 1 0 0 1 1 1 1 Polyubiquitination (PEST) N-terminal domain of MAGUK SH3_1 PF00018.23 KFM08878.1 - 6.3e-09 35.0 0.0 1.6e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFM08878.1 - 6.5e-09 35.1 0.0 2.4e-08 33.3 0.0 2.0 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KFM08878.1 - 6.6e-05 22.4 1.2 0.00051 19.5 0.0 3.0 4 0 0 4 4 4 1 Variant SH3 domain LsmAD PF06741.8 KFM08881.1 - 0.015 15.3 1.7 0.016 15.2 1.2 1.0 1 0 0 1 1 1 0 LsmAD domain L27_1 PF09058.5 KFM08881.1 - 0.022 14.6 0.7 0.04 13.7 0.1 1.7 2 0 0 2 2 2 0 L27_1 DUF1370 PF07114.6 KFM08882.1 - 1.1e-69 233.4 0.4 1.3e-69 233.1 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1370) DsbB PF02600.11 KFM08882.1 - 0.36 10.6 3.7 1.1 9.0 0.0 2.7 2 1 1 3 3 3 0 Disulfide bond formation protein DsbB Ebp2 PF05890.7 KFM08884.1 - 0.00014 21.2 3.8 0.00014 21.2 2.6 1.6 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 Erp_C PF06780.6 KFM08884.1 - 0.0038 17.0 12.3 0.0038 17.0 8.5 2.1 1 1 1 2 2 2 1 Erp protein C-terminus DUF4618 PF15397.1 KFM08884.1 - 0.04 13.2 19.7 0.048 12.9 13.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) T4SS PF07996.6 KFM08884.1 - 0.097 12.5 5.3 0.073 12.9 1.7 1.9 2 0 0 2 2 2 0 Type IV secretion system proteins TMCO5 PF14992.1 KFM08884.1 - 0.2 10.7 18.5 0.74 8.8 12.7 1.8 1 1 0 1 1 1 0 TMCO5 family TFR_dimer PF04253.10 KFM08884.1 - 0.52 9.9 3.5 3.8 7.0 0.1 2.5 2 1 1 3 3 3 0 Transferrin receptor-like dimerisation domain ERM PF00769.14 KFM08884.1 - 1 8.8 20.0 0.76 9.2 8.5 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF1664 PF07889.7 KFM08884.1 - 1.2 8.8 10.4 0.34 10.7 1.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4446 PF14584.1 KFM08884.1 - 2 8.2 12.5 1.2 8.9 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) DUF3573 PF12097.3 KFM08884.1 - 2.6 6.5 5.6 4.3 5.8 0.4 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3573) IncA PF04156.9 KFM08884.1 - 3 7.3 23.3 1.4e+04 -4.6 16.1 2.9 1 1 0 1 1 0 0 IncA protein DUF745 PF05335.8 KFM08884.1 - 3.9 6.9 8.4 2.4 7.6 1.8 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF745) NAD_binding_5 PF07994.7 KFM08884.1 - 8.2 5.8 7.2 3.6 6.9 2.6 1.8 1 1 1 2 2 2 0 Myo-inositol-1-phosphate synthase DUF972 PF06156.8 KFM08884.1 - 9.2 6.6 18.0 4.3 7.7 1.1 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Cauli_AT PF03233.8 KFM08884.1 - 9.3 5.9 13.1 7 6.3 4.6 2.4 1 1 1 2 2 2 0 Aphid transmission protein ANTH PF07651.11 KFM08886.1 - 7.5e-82 274.1 0.6 1e-81 273.7 0.4 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 KFM08886.1 - 2.9e-13 49.7 0.1 5.9e-13 48.7 0.1 1.5 1 0 0 1 1 1 1 ENTH domain DUF3824 PF12868.2 KFM08886.1 - 0.04 14.8 0.1 0.04 14.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) T2SM PF04612.7 KFM08886.1 - 0.35 10.6 2.6 0.69 9.6 1.8 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M EF-1_beta_acid PF10587.4 KFM08886.1 - 0.8 9.9 5.4 1.6 8.9 3.8 1.5 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region WD40 PF00400.27 KFM08887.1 - 1.6e-14 53.1 4.1 3.1e-06 26.8 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 KFM08887.1 - 0.0052 14.9 0.0 0.0078 14.4 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Lipoprotein_3 PF00938.12 KFM08887.1 - 0.059 13.1 1.1 0.082 12.6 0.0 1.7 2 0 0 2 2 2 0 Lipoprotein Ion_trans PF00520.26 KFM08888.1 - 4.7e-37 127.2 17.2 4.7e-37 127.2 11.9 2.0 3 0 0 3 3 3 1 Ion transport protein TRP_2 PF08344.6 KFM08888.1 - 1.1e-30 105.3 1.4 2.3e-30 104.3 1.0 1.6 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_2 PF12796.2 KFM08888.1 - 2.9e-13 49.9 1.3 3.2e-09 37.0 0.3 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) PKD_channel PF08016.7 KFM08888.1 - 5.1e-13 48.2 13.1 8.9e-13 47.4 9.1 1.4 1 0 0 1 1 1 1 Polycystin cation channel Ank PF00023.25 KFM08888.1 - 7.3e-09 35.0 3.9 0.066 13.0 0.0 4.8 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 KFM08888.1 - 1.6e-08 34.8 0.5 3.6e-06 27.3 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM08888.1 - 7e-07 29.3 1.8 0.042 14.1 0.1 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM08888.1 - 8.5e-06 25.5 4.7 8.9 6.8 0.1 5.0 4 0 0 4 4 4 2 Ankyrin repeat ING PF12998.2 KFM08888.1 - 0.077 13.2 8.9 0.11 12.8 4.3 2.2 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Prog_receptor PF02161.10 KFM08889.1 - 4.7e-27 95.0 3.5 5.8e-27 94.7 2.4 1.1 1 0 0 1 1 1 1 Progesterone receptor zf-C4 PF00105.13 KFM08889.1 - 1.1e-26 92.8 15.6 1.1e-26 92.8 10.8 1.5 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 KFM08889.1 - 4.7e-26 91.1 7.3 6.8e-26 90.6 5.1 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Neur_chan_memb PF02932.11 KFM08891.1 - 5e-55 186.9 1.3 2.3e-54 184.7 0.9 1.8 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 KFM08891.1 - 1.1e-40 139.0 0.0 1.7e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain OAD_gamma PF04277.8 KFM08891.1 - 0.015 15.6 0.1 0.15 12.4 0.0 2.2 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain OrgA_MxiK PF09482.5 KFM08892.1 - 0.12 12.0 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial type III secretion apparatus protein (OrgA_MxiK) Neur_chan_LBD PF02931.18 KFM08893.1 - 4.3e-51 173.1 0.0 6e-51 172.6 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFM08893.1 - 4.3e-47 160.9 5.6 1.6e-39 136.2 1.7 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_memb PF02932.11 KFM08894.1 - 1.6e-44 152.5 12.0 1.1e-39 136.7 6.1 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 KFM08894.1 - 6e-39 133.4 2.9 8.8e-39 132.8 2.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain RDD PF06271.7 KFM08894.1 - 0.34 10.7 7.2 1 9.2 5.0 1.9 1 1 0 1 1 1 0 RDD family CitMHS PF03600.11 KFM08895.1 - 1.5e-73 247.4 17.7 1.2e-69 234.5 6.6 2.2 1 1 1 2 2 2 2 Citrate transporter Na_sulph_symp PF00939.14 KFM08895.1 - 1.7e-15 56.8 32.2 2.2e-10 39.9 9.2 2.5 2 1 0 2 2 2 2 Sodium:sulfate symporter transmembrane region ArsB PF02040.10 KFM08895.1 - 2.4e-12 46.5 25.9 5.8e-08 32.1 7.1 2.2 2 0 0 2 2 2 2 Arsenical pump membrane protein Mg_trans_NIPA PF05653.9 KFM08897.1 - 6.7e-70 235.4 14.9 7.5e-70 235.2 10.3 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 KFM08897.1 - 0.0081 16.1 4.8 0.0081 16.1 3.3 3.2 2 1 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 KFM08897.1 - 0.027 14.6 0.6 0.027 14.6 0.4 3.6 2 1 1 3 3 3 0 Multidrug resistance efflux transporter MgtE PF01769.11 KFM08897.1 - 0.29 11.3 9.4 0.15 12.3 0.3 2.5 1 1 1 2 2 2 0 Divalent cation transporter TPT PF03151.11 KFM08897.1 - 0.31 10.6 17.2 1 8.9 6.5 2.6 2 1 0 2 2 2 0 Triose-phosphate Transporter family DUF2678 PF10856.3 KFM08897.1 - 0.38 10.5 16.2 1.3 8.7 1.7 3.4 2 2 2 4 4 4 0 Protein of unknown function (DUF2678) Cortexin PF11057.3 KFM08897.1 - 0.42 10.2 3.0 0.32 10.6 0.2 2.1 2 0 0 2 2 2 0 Cortexin of kidney Mg_trans_NIPA PF05653.9 KFM08898.1 - 3.8e-147 489.0 14.0 4.4e-147 488.8 9.7 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 KFM08898.1 - 3.9e-09 36.7 1.8 3.9e-09 36.7 1.2 3.2 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KFM08898.1 - 4.7e-08 33.1 5.7 4.7e-08 33.1 3.9 3.9 3 1 1 4 4 4 1 EamA-like transporter family fn3 PF00041.16 KFM08899.1 - 1.7e-05 24.8 0.1 3.1e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III domain FAM163 PF15069.1 KFM08899.1 - 0.04 14.4 0.5 0.15 12.6 0.0 2.1 2 1 0 2 2 2 0 FAM163 family Interfer-bind PF09294.5 KFM08899.1 - 0.053 13.5 0.3 0.087 12.8 0.2 1.4 1 0 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III CoA_binding_3 PF13727.1 KFM08899.1 - 0.06 13.1 0.0 0.083 12.7 0.0 1.3 1 0 0 1 1 1 0 CoA-binding domain CD34_antigen PF06365.7 KFM08899.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family Spc97_Spc98 PF04130.8 KFM08900.1 - 2.6e-113 379.2 13.9 3.1e-113 378.9 9.6 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family GCP5-Mod21 PF14609.1 KFM08900.1 - 0.00035 18.8 1.4 0.0015 16.7 0.1 2.4 2 0 0 2 2 2 1 gamma-Tubulin ring complex non-core subunit mod21 GD_AH_C PF04295.8 KFM08900.1 - 0.24 10.0 0.0 0.39 9.3 0.0 1.2 1 0 0 1 1 1 0 D-galactarate dehydratase / Altronate hydrolase, C terminus Na_H_Exchanger PF00999.16 KFM08901.1 - 1.4e-81 274.0 31.7 1.7e-81 273.6 22.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TBCC PF07986.7 KFM08902.1 - 1.3e-44 150.4 5.2 2.1e-44 149.7 3.6 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C NDK PF00334.14 KFM08902.1 - 0.0001 22.0 0.0 0.00018 21.2 0.0 1.4 1 0 0 1 1 1 1 Nucleoside diphosphate kinase CAP_C PF08603.6 KFM08902.1 - 0.001 18.4 1.1 0.0018 17.6 0.7 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal zf-HC5HC2H_2 PF13832.1 KFM08903.1 - 1e-30 105.9 7.9 1e-30 105.9 5.5 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KFM08903.1 - 3.5e-25 87.9 6.0 3.5e-25 87.9 4.2 3.3 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.4 KFM08903.1 - 1.1e-22 80.9 0.4 1.1e-22 80.9 0.3 2.8 3 0 0 3 3 3 1 Enhancer of polycomb-like PHD_2 PF13831.1 KFM08903.1 - 1.9e-12 46.2 6.8 1.9e-12 46.2 4.7 3.6 4 0 0 4 4 4 1 PHD-finger PHD PF00628.24 KFM08903.1 - 1.4e-09 37.4 9.4 1.4e-09 37.4 6.5 3.5 2 1 1 3 3 3 2 PHD-finger C1_1 PF00130.17 KFM08903.1 - 0.0019 17.9 2.8 0.0019 17.9 2.0 3.8 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 KFM08903.1 - 0.63 9.8 19.1 0.081 12.6 4.4 2.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 SGL PF08450.7 KFM08904.1 - 2.4e-79 266.1 0.1 2.8e-79 265.9 0.1 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Reg_prop PF07494.6 KFM08904.1 - 0.031 14.2 0.0 0.29 11.2 0.0 2.6 2 0 0 2 2 2 0 Two component regulator propeller NHL PF01436.16 KFM08904.1 - 0.04 13.8 0.0 0.12 12.4 0.0 1.9 1 0 0 1 1 1 0 NHL repeat PQQ_2 PF13360.1 KFM08904.1 - 0.077 12.4 0.0 0.93 8.9 0.0 2.1 2 0 0 2 2 2 0 PQQ-like domain GRASP55_65 PF04495.9 KFM08904.1 - 0.14 12.1 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain SGL PF08450.7 KFM08905.1 - 9.6e-80 267.5 0.0 1.1e-79 267.3 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Reg_prop PF07494.6 KFM08905.1 - 0.057 13.4 0.0 1 9.6 0.0 2.9 2 0 0 2 2 2 0 Two component regulator propeller Ldh_2 PF02615.9 KFM08905.1 - 0.11 11.2 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 Malate/L-lactate dehydrogenase Kelch_6 PF13964.1 KFM08905.1 - 0.56 10.4 2.2 13 6.1 0.0 3.1 3 1 1 4 4 4 0 Kelch motif PI-PLC-X PF00388.14 KFM08906.1 - 8.7e-06 25.1 0.4 2.1e-05 23.9 0.2 1.8 1 1 1 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain MMR_HSR1 PF01926.18 KFM08907.1 - 3.4e-14 52.8 0.2 1.3e-13 50.9 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP-bdg_N PF13167.1 KFM08907.1 - 1e-05 25.5 0.1 3.3e-05 23.9 0.1 1.9 1 0 0 1 1 1 1 GTP-binding GTPase N-terminal GTP_EFTU PF00009.22 KFM08907.1 - 0.00079 18.9 0.2 0.31 10.4 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 KFM08907.1 - 0.00097 18.6 0.2 0.04 13.4 0.0 2.8 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 KFM08907.1 - 0.0022 17.2 1.1 0.01 15.1 0.8 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B Rad17 PF03215.10 KFM08907.1 - 0.0077 14.9 0.3 0.61 8.6 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 KFM08907.1 - 0.014 15.1 0.2 0.054 13.1 0.0 2.0 1 1 1 2 2 2 0 Archaeal ATPase MobB PF03205.9 KFM08907.1 - 0.015 15.0 0.1 0.04 13.6 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 KFM08907.1 - 0.026 15.0 0.0 0.074 13.5 0.0 1.9 1 1 0 1 1 1 0 Miro-like protein Adeno_IVa2 PF02456.10 KFM08907.1 - 0.031 12.9 0.0 0.1 11.1 0.0 1.8 1 1 0 1 1 1 0 Adenovirus IVa2 protein AAA_16 PF13191.1 KFM08907.1 - 0.051 13.5 0.0 0.094 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 KFM08907.1 - 0.051 13.8 1.0 0.09 13.0 0.2 2.1 1 1 1 2 2 2 0 ABC transporter Dynamin_N PF00350.18 KFM08907.1 - 0.069 12.9 0.1 0.28 10.9 0.0 2.1 2 1 1 3 3 3 0 Dynamin family AAA_14 PF13173.1 KFM08907.1 - 0.076 12.9 0.0 0.24 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain STAG PF08514.6 KFM08908.1 - 4.7e-38 129.5 0.3 4.7e-38 129.5 0.2 2.6 2 0 0 2 2 2 1 STAG domain BCL_N PF04714.8 KFM08909.1 - 0.17 11.4 0.5 0.21 11.1 0.3 1.2 1 0 0 1 1 1 0 BCL7, N-terminal conserver region EF-hand_7 PF13499.1 KFM08910.1 - 3.3e-19 68.7 3.9 8.1e-16 57.9 2.7 3.8 1 1 2 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 KFM08910.1 - 2.7e-10 38.7 0.1 0.033 13.4 0.0 6.0 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.1 KFM08910.1 - 3.2e-08 32.7 0.5 0.12 12.3 0.0 6.0 6 0 0 6 6 6 2 EF-hand domain EF-hand_8 PF13833.1 KFM08910.1 - 7.3e-08 31.9 0.1 0.55 9.8 0.0 6.2 6 0 0 6 6 6 1 EF-hand domain pair EF-hand_5 PF13202.1 KFM08910.1 - 1.3e-06 27.4 0.1 0.00061 19.0 0.0 4.1 5 0 0 5 5 5 1 EF hand DUF4187 PF13821.1 KFM08910.1 - 0.031 13.8 0.9 0.083 12.4 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) SBP_bac_6 PF13343.1 KFM08910.1 - 0.089 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein SPARC_Ca_bdg PF10591.4 KFM08910.1 - 0.29 11.1 7.8 1.9 8.5 0.2 3.0 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Homeobox PF00046.24 KFM08911.1 - 2.3e-25 87.9 2.7 3.8e-25 87.2 1.8 1.4 1 0 0 1 1 1 1 Homeobox domain MRP-L20 PF12824.2 KFM08911.1 - 0.0028 17.6 0.4 0.0052 16.7 0.2 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Homeobox_KN PF05920.6 KFM08911.1 - 0.0046 16.6 0.2 0.015 15.0 0.0 1.9 2 0 0 2 2 2 1 Homeobox KN domain Cation_ATPase_N PF00690.21 KFM08912.1 - 0.2 11.1 0.7 0.34 10.4 0.5 1.3 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus Tissue_fac PF01108.12 KFM08912.1 - 0.63 9.8 4.2 3.2 7.5 0.2 2.8 3 0 0 3 3 3 0 Tissue factor DUF131 PF01998.12 KFM08912.1 - 1.5 8.2 4.0 3.4 7.0 2.8 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF131 IL6Ra-bind PF09240.5 KFM08913.1 - 4.4e-25 87.7 1.5 8.1e-25 86.8 1.0 1.4 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding Tissue_fac PF01108.12 KFM08913.1 - 0.0094 15.6 1.3 1.5 8.5 0.0 2.2 2 0 0 2 2 2 2 Tissue factor EpoR_lig-bind PF09067.5 KFM08913.1 - 0.5 10.3 4.7 0.14 12.1 0.9 1.8 2 0 0 2 2 2 0 Erythropoietin receptor, ligand binding IL4Ra_N PF09238.5 KFM08913.1 - 0.83 9.8 4.4 0.68 10.0 0.7 2.1 1 1 1 2 2 2 0 Interleukin-4 receptor alpha chain, N-terminal IL6Ra-bind PF09240.5 KFM08914.1 - 1.1e-19 70.3 0.3 2.2e-19 69.4 0.0 1.6 2 0 0 2 2 2 1 Interleukin-6 receptor alpha chain, binding Pathogen_betaC1 PF09593.5 KFM08914.1 - 0.041 13.5 1.1 0.38 10.4 0.1 2.1 1 1 1 2 2 2 0 Beta-satellite pathogenicity beta C1 protein IL6Ra-bind PF09240.5 KFM08915.1 - 2.2e-25 88.6 0.1 4.4e-25 87.7 0.0 1.5 2 0 0 2 2 2 1 Interleukin-6 receptor alpha chain, binding EpoR_lig-bind PF09067.5 KFM08915.1 - 0.00057 19.8 1.4 0.00085 19.2 0.5 1.6 2 0 0 2 2 2 1 Erythropoietin receptor, ligand binding Mito_carr PF00153.22 KFM08916.1 - 2.1e-57 190.7 1.4 2.4e-22 78.4 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Methyltransf_2 PF00891.13 KFM08917.1 - 6e-52 176.2 0.0 1.1e-51 175.4 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Maf PF02545.9 KFM08917.1 - 1.2e-46 158.2 0.0 2e-46 157.5 0.0 1.3 1 0 0 1 1 1 1 Maf-like protein Methyltransf_23 PF13489.1 KFM08917.1 - 5.8e-08 32.6 0.0 3.5e-07 30.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFM08917.1 - 2.6e-06 27.9 0.0 1.2e-05 25.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFM08917.1 - 2.4e-05 24.6 0.0 0.00029 21.1 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFM08917.1 - 3.6e-05 24.1 0.0 0.00016 22.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain 7tm_1 PF00001.16 KFM08918.1 - 5.2e-44 150.3 27.0 6.9e-44 149.9 18.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) VHS PF00790.14 KFM08918.1 - 0.037 13.6 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 VHS domain Endomucin PF07010.7 KFM08918.1 - 0.13 11.6 0.5 0.26 10.5 0.3 1.4 1 0 0 1 1 1 0 Endomucin RRM_1 PF00076.17 KFM08919.1 - 0.0013 18.3 0.5 0.94 9.1 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_2 PF00891.13 KFM08920.1 - 2.9e-72 242.7 0.0 3.7e-72 242.3 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KFM08920.1 - 4.7e-09 36.8 0.0 1e-08 35.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFM08920.1 - 3.4e-06 27.4 0.0 6.8e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFM08920.1 - 7.4e-06 25.7 0.0 1.9e-05 24.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFM08920.1 - 1.3e-05 25.4 0.0 3.1e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFM08920.1 - 0.0004 19.9 0.0 0.00064 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Dimerisation PF08100.6 KFM08920.1 - 0.0022 17.7 0.0 0.0042 16.8 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain RrnaAD PF00398.15 KFM08920.1 - 0.0037 16.3 0.0 0.0057 15.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.7 KFM08920.1 - 0.0044 17.4 0.0 0.012 16.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KFM08920.1 - 0.0071 15.7 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PerB PF06590.6 KFM08920.1 - 0.14 12.4 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 PerB protein adh_short PF00106.20 KFM08922.1 - 1.4e-11 44.6 0.0 1e-10 41.7 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KFM08922.1 - 0.044 13.2 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Dimer_Tnp_hAT PF05699.9 KFM08923.1 - 2e-14 52.9 0.1 6e-14 51.4 0.1 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.10 KFM08923.1 - 4.4e-12 45.5 1.0 1e-11 44.4 0.7 1.6 1 0 0 1 1 1 1 BED zinc finger DUF4413 PF14372.1 KFM08923.1 - 0.00076 19.4 4.4 0.0012 18.7 0.4 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4413) CD99L2 PF12301.3 KFM08924.1 - 3.6e-20 72.3 0.2 4.2e-20 72.1 0.2 1.1 1 0 0 1 1 1 1 CD99 antigen like protein 2 DUF4199 PF13858.1 KFM08924.1 - 0.054 13.4 0.4 0.07 13.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) ENOD93 PF03386.9 KFM08924.1 - 0.087 12.5 0.6 0.11 12.1 0.4 1.2 1 0 0 1 1 1 0 Early nodulin 93 ENOD93 protein Glycophorin_A PF01102.13 KFM08924.1 - 0.16 11.7 0.2 0.24 11.1 0.1 1.3 1 1 0 1 1 1 0 Glycophorin A CD99L2 PF12301.3 KFM08925.1 - 3.4e-21 75.6 0.0 5.5e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 CD99 antigen like protein 2 Glyco_transf_8 PF01501.15 KFM08926.1 - 1.5e-41 142.4 0.0 2.3e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 KFM08926.1 - 0.0033 16.8 0.0 0.0061 15.9 0.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative Nucleotid_trans PF03407.11 KFM08926.1 - 0.0037 17.0 0.0 0.0067 16.2 0.0 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Sulfatase_C PF14707.1 KFM08927.1 - 2.8e-52 176.4 0.1 4.8e-52 175.7 0.1 1.4 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Sulfatase PF00884.18 KFM08927.1 - 1.9e-43 148.7 0.0 3e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KFM08927.1 - 0.00012 21.5 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase MFS_1 PF07690.11 KFM08927.1 - 0.027 13.2 0.8 0.039 12.6 0.5 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF3040 PF11239.3 KFM08927.1 - 0.16 12.0 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) MFS_2 PF13347.1 KFM08927.1 - 0.44 8.8 4.5 0.69 8.2 3.1 1.2 1 0 0 1 1 1 0 MFS/sugar transport protein Sulfatase PF00884.18 KFM08928.1 - 5.4e-85 285.2 0.0 6.9e-85 284.9 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 KFM08928.1 - 1.1e-52 177.8 0.1 1.7e-52 177.1 0.0 1.3 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.17 KFM08928.1 - 1e-11 44.8 0.0 2.4e-11 43.5 0.0 1.4 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KFM08928.1 - 0.16 10.3 0.0 0.24 9.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Sulfatase PF00884.18 KFM08929.1 - 4e-85 285.6 0.0 5.2e-85 285.3 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 KFM08929.1 - 5.1e-52 175.6 0.1 8.3e-52 174.9 0.0 1.3 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.17 KFM08929.1 - 1.1e-11 44.6 0.1 9e-05 21.9 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KFM08929.1 - 0.11 10.9 0.0 0.14 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) I-set PF07679.11 KFM08930.1 - 6e-162 526.0 0.0 9.7e-16 57.4 0.0 13.4 13 0 0 13 13 13 12 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM08930.1 - 1.4e-107 351.9 4.0 1.5e-11 44.2 0.0 13.3 13 0 0 13 13 13 12 Immunoglobulin domain Ig_3 PF13927.1 KFM08930.1 - 2.5e-77 255.2 30.6 1.8e-09 37.9 0.1 14.9 13 1 0 13 13 13 12 Immunoglobulin domain V-set PF07686.12 KFM08930.1 - 6.9e-61 203.1 11.9 7.8e-06 25.7 0.0 14.7 13 2 1 14 14 14 11 Immunoglobulin V-set domain ig PF00047.20 KFM08930.1 - 5.5e-59 196.1 12.8 4.3e-06 26.7 0.0 13.3 13 1 0 13 13 13 10 Immunoglobulin domain LRR_8 PF13855.1 KFM08930.1 - 2.3e-28 97.6 10.0 1.5e-11 43.8 1.2 3.8 1 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KFM08930.1 - 2.7e-15 55.5 3.0 0.0022 17.5 0.0 4.6 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) Receptor_2B4 PF11465.3 KFM08930.1 - 4.5e-08 32.9 0.3 8.3 6.3 0.0 8.2 10 0 0 10 10 10 1 Natural killer cell receptor 2B4 Sp38 PF07354.7 KFM08930.1 - 2.8e-07 29.4 0.1 0.72 8.4 0.0 6.2 7 1 1 8 8 8 3 Zona-pellucida-binding protein (Sp38) LRR_1 PF00560.28 KFM08930.1 - 6.7e-06 25.4 8.1 7.3 7.0 0.0 7.4 7 0 0 7 7 7 1 Leucine Rich Repeat Pkinase PF00069.20 KFM08931.1 - 1.3e-65 221.1 0.0 1.4e-65 221.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM08931.1 - 3.9e-33 114.6 0.0 4.8e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM08931.1 - 2.1e-07 30.2 0.0 3.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFM08931.1 - 0.0066 16.2 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KFM08931.1 - 0.067 12.2 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KFM08931.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL CagZ PF09053.5 KFM08931.1 - 0.14 11.4 0.1 0.3 10.3 0.1 1.5 1 0 0 1 1 1 0 CagZ cNMP_binding PF00027.24 KFM08932.1 - 3.1e-20 71.7 0.0 5.7e-20 70.9 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.26 KFM08932.1 - 6.6e-17 61.4 10.0 1.5e-16 60.2 6.9 1.6 1 1 0 1 1 1 1 Ion transport protein Ion_trans_N PF08412.5 KFM08932.1 - 4.2e-12 45.2 1.2 4.2e-12 45.2 0.8 2.2 2 0 0 2 2 2 1 Ion transport protein N-terminal Ion_trans_2 PF07885.11 KFM08932.1 - 0.01 15.5 0.5 0.01 15.5 0.4 2.1 2 0 0 2 2 2 1 Ion channel DUF1759 PF03564.10 KFM08932.1 - 0.044 13.5 0.9 0.4 10.4 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1759) Elicitin PF00964.12 KFM08932.1 - 0.11 12.4 0.4 0.56 10.1 0.0 2.2 2 0 0 2 2 2 0 Elicitin PDCD9 PF07147.7 KFM08933.1 - 2.6e-135 451.5 0.0 2.9e-135 451.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S30 (PDCD9) RVT_1 PF00078.22 KFM08935.1 - 5.4e-19 68.4 0.0 7.5e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LLGL PF08366.8 KFM08936.1 - 9.9e-44 147.5 0.0 2e-43 146.5 0.0 1.6 1 0 0 1 1 1 1 LLGL2 WD40 PF00400.27 KFM08936.1 - 3.4e-13 48.9 7.4 0.00013 21.6 0.5 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat Lgl_C PF08596.5 KFM08936.1 - 2.1e-07 29.7 0.0 1.2e-05 23.9 0.0 3.2 4 0 0 4 4 4 1 Lethal giant larvae(Lgl) like, C-terminal Synaptobrevin PF00957.16 KFM08936.1 - 0.0024 17.4 0.0 0.0071 15.9 0.0 1.7 1 0 0 1 1 1 1 Synaptobrevin DUF3312 PF11768.3 KFM08936.1 - 0.0063 14.7 0.0 0.022 12.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3312) Apc4_WD40 PF12894.2 KFM08936.1 - 0.012 15.1 0.1 0.094 12.2 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain ACTH_domain PF00976.13 KFM08936.1 - 0.025 14.4 0.5 0.059 13.2 0.3 1.6 1 0 0 1 1 1 0 Corticotropin ACTH domain Sulfotransfer_2 PF03567.9 KFM08938.1 - 2.8e-33 115.6 1.2 3.6e-33 115.3 0.8 1.1 1 0 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.6 KFM08938.1 - 3.9e-08 32.3 0.3 5.4e-08 31.8 0.2 1.2 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase CUE PF02845.11 KFM08940.1 - 2e-09 36.7 0.1 3.7e-09 35.8 0.1 1.5 1 0 0 1 1 1 1 CUE domain zf-RanBP PF00641.13 KFM08940.1 - 1.2e-05 24.3 2.0 2.8e-05 23.1 1.4 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DivIC PF04977.10 KFM08940.1 - 0.053 13.0 3.2 0.34 10.4 1.9 2.1 2 0 0 2 2 2 0 Septum formation initiator IncA PF04156.9 KFM08940.1 - 0.3 10.6 4.8 0.54 9.8 3.3 1.3 1 0 0 1 1 1 0 IncA protein RNase_Zc3h12a PF11977.3 KFM08941.1 - 3.8e-62 208.7 0.0 6.1e-62 208.0 0.0 1.3 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain zf-CCCH PF00642.19 KFM08941.1 - 0.0036 16.9 5.6 0.0083 15.7 2.7 2.4 1 1 1 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KFM08941.1 - 0.089 12.8 9.6 0.18 11.8 6.7 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Omega-toxin PF06357.6 KFM08941.1 - 0.64 9.6 5.0 1.5 8.4 3.4 1.6 1 0 0 1 1 1 0 Omega-atracotoxin Pro_isomerase PF00160.16 KFM08942.1 - 1.3e-30 106.6 0.4 3e-30 105.4 0.3 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 KFM08942.1 - 4.7e-18 64.5 0.0 9.6e-18 63.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM08942.1 - 4.8e-12 45.6 0.0 9.7e-12 44.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM08942.1 - 5.7e-09 35.6 0.9 1.1e-08 34.8 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA PF00004.24 KFM08944.1 - 7.2e-40 136.2 0.0 1.4e-39 135.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 KFM08944.1 - 1.1e-07 31.6 0.0 2.5e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.9 KFM08944.1 - 4.8e-06 26.5 0.1 1.4e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 KFM08944.1 - 1.2e-05 25.2 0.0 4.3e-05 23.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 KFM08944.1 - 1.6e-05 24.1 0.0 4.8e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KFM08944.1 - 0.00044 20.3 0.3 0.004 17.2 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFM08944.1 - 0.00063 19.4 0.4 0.0032 17.2 0.2 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 KFM08944.1 - 0.001 17.9 0.0 0.0019 17.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 KFM08944.1 - 0.0011 18.4 0.0 0.0027 17.1 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 KFM08944.1 - 0.0012 19.6 0.1 0.0053 17.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KFM08944.1 - 0.0012 18.4 0.6 0.01 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KFM08944.1 - 0.0014 18.5 0.0 0.0051 16.7 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 KFM08944.1 - 0.0015 18.2 0.0 0.0036 17.0 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KFM08944.1 - 0.0016 18.4 0.0 0.0043 17.0 0.0 1.8 2 1 0 2 2 1 1 AAA ATPase domain Mg_chelatase PF01078.16 KFM08944.1 - 0.0027 16.9 0.0 0.0061 15.7 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TPR_8 PF13181.1 KFM08944.1 - 0.0062 16.2 0.2 0.024 14.3 0.2 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat KaiC PF06745.8 KFM08944.1 - 0.0063 15.6 0.5 0.98 8.4 0.1 2.6 2 1 1 3 3 2 1 KaiC PhoH PF02562.11 KFM08944.1 - 0.0099 15.1 0.0 0.019 14.1 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein Zeta_toxin PF06414.7 KFM08944.1 - 0.013 14.5 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.1 KFM08944.1 - 0.048 13.2 1.3 0.2 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KFM08944.1 - 0.049 13.3 0.1 0.26 10.9 0.0 2.1 1 1 1 2 2 2 0 NACHT domain AAA_18 PF13238.1 KFM08944.1 - 0.05 13.9 3.4 0.15 12.3 0.0 3.0 3 0 0 3 3 2 0 AAA domain ABC_tran PF00005.22 KFM08944.1 - 0.053 13.8 0.0 0.33 11.2 0.0 2.2 2 0 0 2 2 2 0 ABC transporter RNA_helicase PF00910.17 KFM08944.1 - 0.056 13.6 0.4 0.14 12.3 0.0 2.0 2 1 0 2 2 1 0 RNA helicase AAA_25 PF13481.1 KFM08944.1 - 0.058 12.7 0.9 0.79 9.0 0.2 2.7 2 1 1 3 3 3 0 AAA domain AAA_28 PF13521.1 KFM08944.1 - 0.064 13.2 0.1 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Guanylate_kin PF00625.16 KFM08944.1 - 0.089 12.2 1.9 0.29 10.5 0.0 2.7 3 0 0 3 3 3 0 Guanylate kinase Sigma54_activ_2 PF14532.1 KFM08944.1 - 0.095 12.7 0.0 0.88 9.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain FluMu_gp41 PF10109.4 KFM08944.1 - 0.12 12.2 0.1 0.32 10.9 0.1 1.7 1 0 0 1 1 1 0 Mu-like prophage FluMu protein gp41 TPR_1 PF00515.23 KFM08944.1 - 0.15 11.7 0.2 0.49 10.0 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Sigma54_activat PF00158.21 KFM08944.1 - 0.15 11.5 0.0 0.52 9.7 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain TPR_2 PF07719.12 KFM08944.1 - 0.31 11.0 1.6 1.1 9.3 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.20 KFM08945.1 - 3.6e-58 196.7 1.8 2.8e-38 131.5 0.0 3.3 4 0 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFM08945.1 - 2.7e-28 98.7 0.0 2.5e-20 72.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase UBA PF00627.26 KFM08945.1 - 9.9e-09 34.7 1.5 2.6e-08 33.4 0.3 2.4 3 0 0 3 3 3 1 UBA/TS-N domain Kinase-like PF14531.1 KFM08945.1 - 0.00065 18.7 0.1 0.0025 16.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KFM08945.1 - 0.0027 17.4 0.4 0.017 14.8 0.2 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_C PF00433.19 KFM08945.1 - 0.0048 17.3 1.0 0.02 15.3 0.7 2.2 1 0 0 1 1 1 1 Protein kinase C terminal domain UBA_3 PF09288.5 KFM08945.1 - 0.041 13.4 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Pox_ser-thr_kin PF05445.6 KFM08945.1 - 0.043 12.6 0.1 0.071 11.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase YjcZ PF13990.1 KFM08945.1 - 0.045 12.8 0.5 0.079 12.0 0.4 1.3 1 0 0 1 1 1 0 YjcZ-like protein DUF2015 PF09435.5 KFM08945.1 - 0.076 12.7 0.4 0.19 11.5 0.3 1.6 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2015) Seadorna_VP7 PF07387.6 KFM08945.1 - 0.21 10.3 0.0 0.34 9.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 WD40 PF00400.27 KFM08946.1 - 7.6e-14 50.9 7.0 0.00044 20.0 0.1 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat CPSF_A PF03178.10 KFM08946.1 - 0.00033 19.8 0.0 0.00057 19.0 0.0 1.3 1 0 0 1 1 1 1 CPSF A subunit region Hira PF07569.6 KFM08946.1 - 0.081 12.1 0.0 11 5.1 0.0 2.9 2 1 1 3 3 3 0 TUP1-like enhancer of split BBS2_Mid PF14783.1 KFM08946.1 - 0.097 12.4 0.0 2.8 7.7 0.0 2.6 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region PCMT PF01135.14 KFM08947.1 - 1.5e-81 272.9 0.0 1.7e-81 272.7 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 KFM08947.1 - 2.3e-08 33.7 0.0 4e-08 32.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFM08947.1 - 3.5e-08 34.0 0.0 5.3e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFM08947.1 - 8.9e-06 26.1 0.0 2.9e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFM08947.1 - 6.6e-05 22.1 0.0 9.1e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 KFM08947.1 - 0.00013 21.1 0.0 0.00015 20.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.1 KFM08947.1 - 0.00016 21.4 0.0 0.00048 19.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.5 KFM08947.1 - 0.00024 20.6 0.0 0.00029 20.3 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 KFM08947.1 - 0.0012 18.8 0.0 0.0074 16.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFM08947.1 - 0.0028 17.9 0.0 0.0045 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFM08947.1 - 0.014 14.7 0.1 0.024 14.0 0.1 1.5 1 1 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.14 KFM08947.1 - 0.015 15.2 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase RrnaAD PF00398.15 KFM08947.1 - 0.047 12.7 0.0 0.059 12.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Fibrillarin PF01269.12 KFM08947.1 - 0.053 12.4 0.0 0.082 11.8 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin Methyltransf_32 PF13679.1 KFM08947.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Ldl_recept_a PF00057.13 KFM08948.1 - 1.2e-06 28.3 12.0 2.2e-06 27.4 8.3 1.4 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Big_3_4 PF13754.1 KFM08948.1 - 0.021 15.1 1.0 0.063 13.6 0.0 2.1 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) DUF4625 PF15418.1 KFM08948.1 - 0.058 13.5 0.0 0.13 12.3 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4625) Nitroreductase PF00881.19 KFM08949.1 - 2.4e-23 82.7 0.0 3.2e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family DUF4062 PF13271.1 KFM08949.1 - 0.024 14.6 0.1 0.15 12.1 0.0 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4062) RhoGEF PF00621.15 KFM08950.1 - 2.1e-45 154.7 1.2 2.1e-45 154.7 0.9 2.2 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.24 KFM08950.1 - 0.0035 17.5 0.1 0.015 15.4 0.1 2.2 1 0 0 1 1 1 1 PH domain PH_10 PF15411.1 KFM08950.1 - 0.028 14.6 0.2 0.096 12.8 0.1 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain FTHFS PF01268.14 KFM08951.1 - 9.4e-248 822.7 1.2 1.2e-247 822.4 0.9 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase WSK PF03832.8 KFM08952.1 - 1.9e-13 49.4 11.6 2.5e-12 45.9 1.7 4.6 5 0 0 5 5 5 2 WSK motif Rabaptin PF03528.10 KFM08953.1 - 4.6 7.2 10.0 0.83 9.5 3.8 2.1 1 1 1 2 2 2 0 Rabaptin BTB PF00651.26 KFM08955.1 - 2.2e-19 69.4 0.2 4.6e-19 68.4 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 KFM08955.1 - 6.7e-13 48.2 22.3 8e-05 22.7 1.7 5.5 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 KFM08955.1 - 7.9e-13 47.9 32.7 0.00052 20.1 1.1 5.0 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-met PF12874.2 KFM08955.1 - 2.3e-08 33.9 21.8 0.13 12.4 0.6 4.8 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 KFM08955.1 - 3.9e-08 33.0 29.2 0.004 17.3 0.9 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM08955.1 - 5.5e-08 32.7 17.4 0.023 14.8 0.1 4.7 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFM08955.1 - 0.0043 16.8 22.6 1.7 8.6 0.2 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KFM08955.1 - 0.026 14.1 19.5 0.25 11.0 0.3 4.3 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.2 KFM08955.1 - 0.11 12.6 17.3 4.3 7.5 0.2 3.5 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) C1_2 PF03107.11 KFM08955.1 - 3.5 7.8 15.1 6.4 6.9 0.1 4.3 4 0 0 4 4 4 0 C1 domain C1_4 PF07975.7 KFM08955.1 - 3.7 7.6 14.3 4.1 7.4 2.9 3.9 3 1 1 4 4 4 0 TFIIH C1-like domain Ribosomal_L37ae PF01780.14 KFM08955.1 - 7.3 6.5 10.4 17 5.3 0.0 3.5 3 1 1 4 4 4 0 Ribosomal L37ae protein family DUF155 PF02582.9 KFM08956.1 - 7.3e-49 166.0 3.3 1e-48 165.5 2.3 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF89 PF01937.14 KFM08957.1 - 9.7e-124 412.7 0.6 1.1e-123 412.5 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Oest_recep PF02159.10 KFM08958.1 - 6.7e-54 181.8 7.6 6.7e-54 181.8 5.2 2.3 2 0 0 2 2 2 1 Oestrogen receptor zf-C4 PF00105.13 KFM08958.1 - 1.2e-31 108.6 13.9 2.2e-31 107.8 9.7 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 KFM08958.1 - 9e-29 100.0 1.6 1.5e-28 99.3 1.1 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor ESR1_C PF12743.2 KFM08958.1 - 3.5e-20 71.2 4.2 3.5e-20 71.2 2.9 1.9 2 0 0 2 2 2 1 Oestrogen-type nuclear receptor final C-terminal Spectrin PF00435.16 KFM08959.1 - 8.7e-130 424.5 818.4 4.9e-12 46.0 6.1 73.3 66 10 10 76 76 76 45 Spectrin repeat CH PF00307.26 KFM08959.1 - 6.5e-28 96.9 21.5 4e-19 68.6 0.0 9.8 9 0 0 9 9 9 2 Calponin homology (CH) domain KASH PF10541.4 KFM08959.1 - 1.1e-26 92.3 6.0 3.3e-26 90.8 4.2 1.9 1 0 0 1 1 1 1 Nuclear envelope localisation domain MtrB PF05440.7 KFM08959.1 - 2.2 8.3 10.5 1.2 9.2 0.1 6.4 6 0 0 6 6 6 0 Tetrahydromethanopterin S-methyltransferase subunit B Myc_target_1 PF15179.1 KFM08960.1 - 9.7e-84 279.8 6.8 1.1e-83 279.7 4.7 1.0 1 0 0 1 1 1 1 Myc target protein 1 Hormone_2 PF00123.15 KFM08961.1 - 4.1e-23 80.8 6.5 9.9e-12 44.4 0.2 2.8 3 0 0 3 3 3 2 Peptide hormone F-box PF00646.28 KFM08962.1 - 4.2e-07 29.4 0.0 9.6e-07 28.3 0.0 1.6 1 0 0 1 1 1 1 F-box domain IBR PF01485.16 KFM08962.1 - 5e-07 29.4 11.1 1.3e-06 28.2 7.7 1.6 1 0 0 1 1 1 1 IBR domain DUF1663 PF07909.6 KFM08962.1 - 0.0049 15.4 0.3 0.0082 14.7 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1663) F-box-like PF12937.2 KFM08962.1 - 0.043 13.5 0.0 0.088 12.5 0.0 1.5 1 0 0 1 1 1 0 F-box-like RGS PF00615.14 KFM08963.1 - 4.3e-36 123.5 1.1 5.6e-36 123.2 0.8 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF4226 PF10774.4 KFM08963.1 - 0.11 12.5 0.0 0.33 11.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) 7tm_1 PF00001.16 KFM08964.1 - 1.4e-62 211.2 24.7 1.6e-62 210.9 17.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 KFM08964.1 - 4.9e-09 35.7 14.6 6.1e-09 35.4 10.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Herpes_US9 PF06072.6 KFM08964.1 - 5.1 7.0 10.0 0.099 12.4 0.5 2.5 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 CTD_bind PF04818.8 KFM08965.1 - 4.3e-17 62.1 0.2 7.9e-17 61.2 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.17 KFM08965.1 - 9.4e-10 37.9 0.0 1.7e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM08965.1 - 1.5e-08 34.3 0.0 2.8e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM08965.1 - 6.9e-07 29.1 0.0 1.5e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1777 PF08648.7 KFM08965.1 - 0.0041 16.8 38.2 0.0041 16.8 26.5 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF1777) Nup35_RRM_2 PF14605.1 KFM08965.1 - 0.17 11.6 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif PH_9 PF15410.1 KFM08966.1 - 3.8e-07 30.2 0.0 1.1e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KFM08966.1 - 6e-07 29.6 0.1 3.9e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 PH domain Mnd1 PF03962.10 KFM08966.1 - 0.0034 17.0 1.4 0.0051 16.5 1.0 1.2 1 0 0 1 1 1 1 Mnd1 family DUF4660 PF15559.1 KFM08966.1 - 0.086 12.9 0.5 0.38 10.8 0.2 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4660) DUF1798 PF08807.5 KFM08966.1 - 0.1 12.3 1.2 0.2 11.3 0.6 1.6 1 1 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) DUF892 PF05974.7 KFM08966.1 - 0.13 12.1 0.9 0.36 10.6 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF892) RhoGEF PF00621.15 KFM08968.1 - 6.7e-27 94.5 1.9 1.5e-26 93.4 0.5 2.2 3 0 0 3 3 3 1 RhoGEF domain Frankia_peptide PF14407.1 KFM08968.1 - 0.096 12.4 0.1 0.76 9.5 0.0 2.4 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. RrnaAD PF00398.15 KFM08969.1 - 7.2e-41 139.9 0.0 8.2e-41 139.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 KFM08969.1 - 0.066 13.2 0.0 0.096 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PMP22_Claudin PF00822.15 KFM08970.1 - 1.3e-28 99.7 8.9 1.8e-28 99.2 6.2 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFM08970.1 - 3.5e-10 39.8 7.2 6.4e-10 38.9 4.9 1.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF3185 PF11381.3 KFM08970.1 - 0.038 13.7 0.6 1.4 8.7 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3185) DUF998 PF06197.8 KFM08970.1 - 0.22 10.8 7.4 0.056 12.7 1.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF998) DUF308 PF03729.8 KFM08970.1 - 0.43 10.5 11.8 3.5 7.6 0.0 3.7 4 0 0 4 4 4 0 Short repeat of unknown function (DUF308) DUF872 PF05915.7 KFM08970.1 - 1 9.2 5.8 0.45 10.3 0.3 2.7 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF872) DUF4064 PF13273.1 KFM08970.1 - 6.3 6.9 8.8 3.4 7.8 0.2 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF4064) NAD_binding_6 PF08030.7 KFM08971.1 - 8.1e-34 116.7 0.0 4.1e-33 114.5 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KFM08971.1 - 8.6e-24 83.4 0.0 1.7e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KFM08971.1 - 8.9e-23 80.7 1.0 1.9e-22 79.6 0.7 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KFM08971.1 - 1.6e-07 31.3 0.0 3e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KFM08971.1 - 0.035 14.6 0.0 0.49 10.9 0.0 2.4 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Yae1_N PF09811.4 KFM08972.1 - 3.8e-05 23.1 41.9 1.5e+04 -10.4 29.1 4.2 1 1 0 1 1 1 0 Essential protein Yae1, N terminal DUF3518 PF12031.3 KFM08974.1 - 5.3e-150 497.3 0.1 9.4e-150 496.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3518) ARID PF01388.16 KFM08974.1 - 1e-27 95.8 0.0 2.1e-27 94.8 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PV-1 PF06637.6 KFM08974.1 - 3 6.2 3.7 5.1 5.5 2.5 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) DUF1358 PF07096.6 KFM08975.1 - 1.2e-45 154.2 5.2 1.3e-45 154.0 3.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1358) Peptidase_C4 PF00863.14 KFM08975.1 - 0.071 12.0 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C4 DUF2613 PF11021.3 KFM08975.1 - 0.2 11.3 1.7 2.2 8.0 1.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2613) DUF3042 PF11240.3 KFM08975.1 - 0.66 9.8 3.2 1.2 8.9 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) zf-DHHC PF01529.15 KFM08976.1 - 1.8e-37 128.3 1.7 1.8e-37 128.3 1.2 1.9 1 1 1 2 2 2 1 DHHC palmitoyltransferase BAR_3_WASP_bdg PF10456.4 KFM08978.1 - 2.5e-110 367.3 0.9 3.3e-110 366.9 0.6 1.2 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein PX PF00787.19 KFM08978.1 - 2.2e-23 82.2 0.2 4.5e-23 81.1 0.2 1.5 1 0 0 1 1 1 1 PX domain SH3_1 PF00018.23 KFM08978.1 - 2.5e-09 36.3 0.3 7.3e-09 34.8 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KFM08978.1 - 3.6e-09 36.0 0.2 1.4e-08 34.2 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KFM08978.1 - 4.2e-08 32.5 0.0 9.1e-08 31.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.5 KFM08978.1 - 0.0015 17.8 0.1 0.53 9.5 0.1 2.4 1 1 1 2 2 2 2 Vps5 C terminal like Tbf5 PF06331.7 KFM08979.1 - 3e-20 71.7 0.1 3.2e-20 71.6 0.1 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 TypeIII_RM_meth PF12564.3 KFM08979.1 - 0.094 12.7 0.2 0.12 12.4 0.2 1.2 1 0 0 1 1 1 0 Type III restriction/modification enzyme methylation subunit Tub PF01167.13 KFM08980.1 - 7.2e-26 90.6 0.5 3.1e-23 82.0 0.0 3.1 2 1 0 2 2 2 2 Tub family SOCS_box PF07525.11 KFM08980.1 - 3.5e-08 33.1 2.1 3.5e-08 33.1 1.4 2.0 2 0 0 2 2 2 1 SOCS box WD40 PF00400.27 KFM08980.1 - 7.8e-06 25.5 2.6 0.0046 16.8 0.0 4.8 5 0 0 5 5 5 1 WD domain, G-beta repeat IKI3 PF04762.7 KFM08980.1 - 0.0032 15.3 0.0 0.0058 14.5 0.0 1.3 1 0 0 1 1 1 1 IKI3 family API5 PF05918.6 KFM08980.1 - 0.2 10.1 2.7 0.31 9.4 1.9 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) MIG-14_Wnt-bd PF06664.7 KFM08981.1 - 9e-118 392.4 32.0 9e-118 392.4 22.2 1.5 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion Tctex-1 PF03645.8 KFM08982.1 - 1.9e-37 127.1 0.8 2.1e-37 127.0 0.5 1.0 1 0 0 1 1 1 1 Tctex-1 family FYVE_2 PF02318.11 KFM08983.1 - 2.2e-18 66.2 13.1 2.2e-18 66.2 9.1 2.3 3 0 0 3 3 3 1 FYVE-type zinc finger C2 PF00168.25 KFM08983.1 - 2.1e-17 62.7 0.0 9.7e-16 57.3 0.0 2.4 2 0 0 2 2 2 1 C2 domain PI3K_C2 PF00792.19 KFM08983.1 - 0.014 15.1 0.0 0.038 13.7 0.0 1.7 1 1 0 1 1 1 0 Phosphoinositide 3-kinase C2 ERM PF00769.14 KFM08984.1 - 2.8e-72 243.2 40.5 2.8e-72 243.2 28.0 2.2 1 1 1 2 2 2 1 Ezrin/radixin/moesin family FERM_C PF09380.5 KFM08984.1 - 7.2e-34 115.8 0.0 2.2e-33 114.3 0.0 1.9 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.13 KFM08984.1 - 4.7e-25 88.2 0.2 4.7e-25 88.2 0.2 3.5 2 1 1 3 3 3 1 FERM central domain FERM_N PF09379.5 KFM08984.1 - 9.1e-19 67.2 3.2 2e-18 66.2 0.1 2.9 3 0 0 3 3 3 1 FERM N-terminal domain DUF3650 PF12368.3 KFM08984.1 - 0.099 12.1 0.2 0.099 12.1 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3650) RhoGAP PF00620.22 KFM08985.1 - 6.9e-42 142.6 0.5 1.6e-41 141.4 0.4 1.6 1 0 0 1 1 1 1 RhoGAP domain Radial_spoke_3 PF06098.6 KFM08986.1 - 2.9e-116 387.5 16.7 3.3e-116 387.3 11.6 1.0 1 0 0 1 1 1 1 Radial spoke protein 3 FBPase PF00316.15 KFM08986.1 - 0.041 12.7 0.0 0.061 12.1 0.0 1.2 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase DUF4574 PF15141.1 KFM08986.1 - 4.2 7.1 9.3 0.29 10.8 2.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4574) SET PF00856.23 KFM08987.1 - 0.011 16.0 0.1 2 8.7 0.0 2.2 1 1 1 2 2 2 0 SET domain zf-C2H2 PF00096.21 KFM08987.1 - 0.084 13.2 8.4 0.13 12.7 0.6 3.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM08987.1 - 0.43 11.0 7.2 0.12 12.8 1.3 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFM08988.1 - 7.6e-20 70.1 59.7 8.6e-05 22.6 3.0 8.7 8 0 0 8 8 8 5 Zinc-finger double domain zf-C2H2 PF00096.21 KFM08988.1 - 7.4e-18 63.7 60.7 0.0014 18.8 5.2 7.7 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM08988.1 - 1.4e-15 56.4 50.8 0.0011 19.0 3.2 7.6 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM08988.1 - 1.9e-07 30.7 30.2 0.0028 17.5 0.0 6.7 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM08988.1 - 5e-06 26.5 31.6 0.065 13.3 0.2 6.1 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFM08988.1 - 0.043 13.9 33.2 4.8 7.3 0.1 4.9 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KFM08988.1 - 0.14 12.4 28.0 2.6 8.3 0.1 5.9 6 0 0 6 6 6 0 Zinc-finger of C2H2 type Viral_protease PF08715.5 KFM08988.1 - 0.14 11.1 3.0 0.11 11.4 0.2 2.0 2 1 1 3 3 3 0 Papain like viral protease LTV PF04180.9 KFM08989.1 - 6.3e-105 352.1 20.6 8.4e-105 351.6 14.3 1.2 1 0 0 1 1 1 1 Low temperature viability protein RPEL PF02755.10 KFM08990.1 - 1.7e-28 97.1 29.0 1e-09 37.3 0.4 4.7 5 0 0 5 5 5 4 RPEL repeat Alpha_L_fucos PF01120.12 KFM08991.1 - 3.2e-100 335.4 1.1 3.7e-100 335.2 0.8 1.0 1 0 0 1 1 1 1 Alpha-L-fucosidase Peroxin-3 PF04882.7 KFM08992.1 - 1.2e-101 340.6 3.3 3.6e-79 266.4 0.1 2.0 1 1 1 2 2 2 2 Peroxin-3 DUF4174 PF13778.1 KFM08992.1 - 0.04 14.0 0.0 0.83 9.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4174) dCMP_cyt_deam_1 PF00383.17 KFM08993.1 - 5.2e-10 38.8 0.8 7.9e-10 38.3 0.6 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 KFM08993.1 - 0.0067 16.2 0.5 0.013 15.3 0.3 1.5 1 1 0 1 1 1 1 Bd3614-like deaminase APOBEC_N PF08210.6 KFM08993.1 - 0.049 13.2 0.1 0.07 12.7 0.1 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain Far-17a_AIG1 PF04750.9 KFM08994.1 - 5.8e-73 244.3 13.3 6.6e-73 244.1 9.2 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein zf-C2H2 PF00096.21 KFM08995.1 - 1.6e-17 62.7 28.7 0.00018 21.6 1.1 5.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KFM08995.1 - 3.6e-12 46.0 22.6 0.00064 19.7 0.8 5.2 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 KFM08995.1 - 2.1e-11 43.4 41.1 5.1e-07 29.6 0.7 5.6 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM08995.1 - 9.6e-06 25.5 31.9 0.02 15.2 0.3 5.3 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.2 KFM08995.1 - 4.8e-05 23.4 25.4 0.007 16.5 1.8 5.1 4 0 0 4 4 4 3 Zinc-finger of C2H2 type NOA36 PF06524.7 KFM08995.1 - 0.41 9.8 22.6 0.78 8.9 9.7 2.3 2 0 0 2 2 2 0 NOA36 protein zf-C2H2_2 PF12756.2 KFM08995.1 - 0.58 10.3 18.5 0.082 13.0 2.1 4.0 2 2 2 4 4 4 0 C2H2 type zinc-finger (2 copies) 7tm_2 PF00002.19 KFM08996.1 - 1.5e-49 168.2 16.6 2.8e-49 167.4 11.5 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) CUB PF00431.15 KFM08996.1 - 7.1e-25 87.2 0.1 1.7e-24 86.0 0.0 1.7 1 0 0 1 1 1 1 CUB domain GPS PF01825.16 KFM08996.1 - 3.3e-17 62.2 0.7 1.1e-16 60.5 0.5 2.0 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain Pentaxin PF00354.12 KFM08996.1 - 8.2e-09 35.1 2.2 8.3e-09 35.1 0.1 2.1 3 0 0 3 3 3 1 Pentaxin family Laminin_G_3 PF13385.1 KFM08996.1 - 0.0028 17.9 0.1 0.0077 16.4 0.0 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF605 PF04652.11 KFM08997.1 - 4.2e-83 279.8 5.0 1.9e-61 208.6 0.1 2.0 1 1 1 2 2 2 2 Vta1 like Connexin_CCC PF10582.4 KFM08998.1 - 1.2e-20 73.1 4.6 3.5e-20 71.5 3.2 1.8 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain Connexin PF00029.14 KFM08998.1 - 8.9e-11 41.8 0.0 8.9e-11 41.8 0.0 2.3 2 1 0 2 2 2 1 Connexin DUF4051 PF13260.1 KFM08998.1 - 0.31 10.3 0.1 0.31 10.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) DUF1290 PF06947.7 KFM08998.1 - 0.37 10.7 3.7 1.8 8.5 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1290) 7tm_1 PF00001.16 KFM08999.1 - 5.2e-54 183.0 13.2 7e-54 182.6 9.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 KFM08999.1 - 4.1e-09 35.9 8.2 5.4e-09 35.5 5.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.4 KFM08999.1 - 3.4e-08 32.9 12.4 4.7e-08 32.5 8.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM08999.1 - 0.097 11.7 15.7 0.018 14.1 7.2 2.2 1 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.4 KFM08999.1 - 0.1 11.7 13.9 0.24 10.4 9.6 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Yae1_N PF09811.4 KFM09000.1 - 2.2e-10 39.9 25.1 0.022 14.3 17.4 2.9 1 1 0 1 1 1 1 Essential protein Yae1, N terminal HECA PF15353.1 KFM09003.1 - 3.5e-39 132.8 8.4 7.5e-39 131.7 5.8 1.6 1 0 0 1 1 1 1 Headcase protein family homologue RecR PF02132.10 KFM09003.1 - 0.045 13.1 3.2 1.7 8.1 0.1 2.9 2 0 0 2 2 2 0 RecR protein zf-ribbon_3 PF13248.1 KFM09003.1 - 0.31 10.2 5.9 6.3 6.1 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 KFM09003.1 - 2.5 7.7 10.8 2.7 7.5 0.5 3.5 3 0 0 3 3 3 0 zinc-ribbon domain Costars PF14705.1 KFM09004.1 - 6.4e-33 112.5 0.4 7.1e-33 112.4 0.3 1.0 1 0 0 1 1 1 1 Costars DUF4061 PF13270.1 KFM09005.1 - 9e-37 125.0 5.3 1.2e-36 124.6 3.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4061) tRNA-synt_His PF13393.1 KFM09005.1 - 0.0026 16.8 0.7 0.0033 16.5 0.5 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase Borrelia_lipo_1 PF05714.6 KFM09005.1 - 0.018 14.1 0.6 0.025 13.6 0.4 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi virulent strain associated lipoprotein PMP22_Claudin PF00822.15 KFM09006.1 - 1.1e-10 41.3 5.4 1.7e-10 40.8 3.7 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFM09006.1 - 2.9e-06 27.0 10.9 6e-06 26.0 7.5 1.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HGMIC_fpl PF10242.4 KFM09006.1 - 0.00065 19.7 8.1 0.0018 18.3 5.6 1.7 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein PalH PF08733.5 KFM09006.1 - 0.18 10.6 5.3 0.23 10.2 3.7 1.1 1 0 0 1 1 1 0 PalH/RIM21 Pox_A14 PF05767.7 KFM09006.1 - 1.8 8.5 9.4 1.5 8.8 4.0 2.2 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 PMP22_Claudin PF00822.15 KFM09007.1 - 2.3e-09 37.1 9.1 3.1e-09 36.7 6.3 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family L_HGMIC_fpl PF10242.4 KFM09007.1 - 0.00045 20.2 7.1 0.0011 19.0 4.9 1.7 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.1 KFM09007.1 - 0.00049 19.8 10.9 0.00081 19.1 7.4 1.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PalH PF08733.5 KFM09007.1 - 0.036 12.8 5.2 0.052 12.3 3.6 1.1 1 0 0 1 1 1 0 PalH/RIM21 zf-LITAF-like PF10601.4 KFM09007.1 - 0.6 10.0 5.6 10 6.0 0.5 2.7 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Pox_A14 PF05767.7 KFM09007.1 - 5 7.1 10.0 0.25 11.3 3.1 1.7 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 zf-A20 PF01754.11 KFM09008.1 - 2.7e-44 148.3 77.8 5.4e-11 41.8 2.7 7.9 7 0 0 7 7 7 7 A20-like zinc finger OTU PF02338.14 KFM09008.1 - 9.2e-27 94.0 0.0 2.7e-26 92.5 0.0 1.9 1 0 0 1 1 1 1 OTU-like cysteine protease HLH PF00010.21 KFM09009.1 - 1.8e-12 46.7 0.2 3.1e-12 45.9 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SLAIN PF15301.1 KFM09009.1 - 0.27 10.3 4.4 0.28 10.2 3.0 1.0 1 0 0 1 1 1 0 SLAIN motif-containing family Yae1_N PF09811.4 KFM09010.1 - 1.8e-12 46.5 30.8 1.1 8.8 21.3 3.2 1 1 0 1 1 1 1 Essential protein Yae1, N terminal Tissue_fac PF01108.12 KFM09012.1 - 2.5e-18 65.7 0.1 3e-18 65.5 0.1 1.1 1 0 0 1 1 1 1 Tissue factor PA28_beta PF02252.13 KFM09012.1 - 0.0014 18.1 0.0 0.0019 17.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit Tissue_fac PF01108.12 KFM09013.1 - 2e-32 111.0 0.8 3.1e-32 110.4 0.6 1.2 1 0 0 1 1 1 1 Tissue factor Interfer-bind PF09294.5 KFM09013.1 - 5.3e-19 68.2 0.3 1.6e-18 66.6 0.0 1.8 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.16 KFM09013.1 - 0.14 12.2 3.2 1.3 9.1 0.9 2.9 3 1 0 3 3 3 0 Fibronectin type III domain Tissue_fac PF01108.12 KFM09014.1 - 2.6e-26 91.4 0.1 7.7e-26 89.9 0.1 1.9 1 0 0 1 1 1 1 Tissue factor Interfer-bind PF09294.5 KFM09014.1 - 1.9e-21 76.1 2.3 2.5e-21 75.7 0.1 2.3 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III TPT PF03151.11 KFM09015.1 - 1.7e-07 30.9 13.8 2.3e-07 30.6 9.6 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family DUF4199 PF13858.1 KFM09015.1 - 0.02 14.8 0.5 0.09 12.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Potyvirid-P3 PF13608.1 KFM09015.1 - 0.092 11.8 0.1 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein VIT1 PF01988.14 KFM09015.1 - 1.2 8.5 5.9 0.29 10.5 1.7 1.7 1 1 1 2 2 2 0 VIT family 7TMR-DISM_7TM PF07695.6 KFM09015.1 - 4 7.0 10.0 12 5.5 6.9 1.8 1 1 0 1 1 1 0 7TM diverse intracellular signalling WD40 PF00400.27 KFM09016.1 - 1.4e-41 138.8 13.4 1.7e-09 37.1 0.0 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 KFM09016.1 - 7.7e-05 22.4 0.1 0.00088 19.0 0.0 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KFM09016.1 - 0.36 8.9 2.8 9.1 4.2 0.0 3.1 2 1 1 4 4 4 0 Nucleoporin Nup120/160 DUF4071 PF13281.1 KFM09017.1 - 2.4e-144 480.7 0.0 2.4e-144 480.7 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4071) Pkinase PF00069.20 KFM09017.1 - 1.6e-63 214.3 0.0 3.7e-63 213.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM09017.1 - 1.2e-41 142.5 0.0 2e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM09017.1 - 0.00054 19.0 0.0 0.0014 17.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like MAP7 PF05672.6 KFM09018.1 - 1.7e-54 183.7 79.4 1.7e-54 183.7 55.0 3.4 3 0 0 3 3 3 1 MAP7 (E-MAP-115) family CARD PF00619.16 KFM09019.1 - 0.077 12.8 0.2 0.2 11.5 0.1 1.7 2 0 0 2 2 2 0 Caspase recruitment domain THRAP3_BCLAF1 PF15440.1 KFM09020.1 - 1.9e-180 601.7 108.1 1.9e-180 601.7 74.9 2.5 3 0 0 3 3 3 1 THRAP3/BCLAF1 family GRP PF07172.6 KFM09020.1 - 0.55 10.7 15.8 0.029 14.8 3.6 3.7 2 1 0 2 2 2 0 Glycine rich protein family Mito_fiss_reg PF05308.6 KFM09021.1 - 7.6e-60 202.4 1.9 1e-59 202.0 1.3 1.2 1 0 0 1 1 1 1 Mitochondrial fission regulator Allexi_40kDa PF05549.6 KFM09021.1 - 0.047 12.9 0.7 0.082 12.1 0.0 1.6 2 0 0 2 2 2 0 Allexivirus 40kDa protein PDEase_I PF00233.14 KFM09022.1 - 3.9e-62 210.0 0.5 5.2e-62 209.6 0.4 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase SNARE PF05739.14 KFM09022.1 - 0.1 12.2 0.7 0.23 11.1 0.5 1.6 1 0 0 1 1 1 0 SNARE domain WD40 PF00400.27 KFM09023.1 - 4.7e-33 111.8 8.1 1.7e-10 40.3 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat SH3_1 PF00018.23 KFM09023.1 - 2.4e-17 62.0 0.1 6.3e-17 60.6 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFM09023.1 - 2.7e-15 55.6 0.0 7.2e-15 54.3 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFM09023.1 - 2.5e-11 42.8 0.0 5.6e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF4648 PF15505.1 KFM09023.1 - 1.2e-05 25.5 1.5 5.8e-05 23.3 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4648) Cmyb_C PF09316.5 KFM09024.1 - 4.7e-71 237.8 3.5 1e-70 236.7 2.4 1.6 1 0 0 1 1 1 1 C-myb, C-terminal Myb_DNA-binding PF00249.26 KFM09024.1 - 1e-51 172.7 19.2 5.1e-17 61.6 1.4 4.1 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFM09024.1 - 1.2e-42 143.8 19.7 3.4e-19 68.6 1.0 3.5 1 1 2 3 3 3 3 Myb-like DNA-binding domain LMSTEN PF07988.7 KFM09024.1 - 3.1e-29 100.0 0.6 5.9e-29 99.1 0.4 1.5 1 0 0 1 1 1 1 LMSTEN motif Rap1_C PF11626.3 KFM09024.1 - 0.056 13.3 9.0 11 5.9 3.0 3.4 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Spore_III_AB PF09548.5 KFM09024.1 - 0.13 12.0 0.1 0.72 9.5 0.0 2.4 2 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) GTP_EFTU PF00009.22 KFM09025.1 - 3.8e-49 166.6 0.0 7.6e-49 165.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 KFM09025.1 - 6e-23 80.7 2.1 1.8e-22 79.2 1.2 1.9 2 0 0 2 2 2 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.12 KFM09025.1 - 4.3e-21 74.9 0.9 2.6e-20 72.4 0.0 2.6 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KFM09025.1 - 4.1e-08 33.2 0.1 2e-07 30.9 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KFM09025.1 - 6.2e-07 29.3 0.2 3e-06 27.1 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KFM09025.1 - 7.8e-05 23.1 1.0 0.0058 17.1 0.1 3.2 2 1 0 2 2 2 1 Miro-like protein GTP_EFTU_D4 PF14578.1 KFM09025.1 - 0.0017 17.9 0.0 0.0044 16.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MobB PF03205.9 KFM09025.1 - 0.004 16.8 0.3 0.51 10.0 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 KFM09025.1 - 0.02 15.0 0.1 0.11 12.6 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.1 KFM09025.1 - 0.38 10.3 0.0 0.38 10.3 0.0 2.5 4 0 0 4 4 4 0 P-loop containing region of AAA domain Aldedh PF00171.17 KFM09026.1 - 2.1e-173 576.9 0.0 2.4e-173 576.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KFM09026.1 - 0.047 12.9 0.1 0.53 9.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Yae1_N PF09811.4 KFM09027.1 - 5e-20 70.7 50.2 4.6e-05 22.8 5.6 5.6 1 1 2 3 3 3 3 Essential protein Yae1, N terminal Pkinase PF00069.20 KFM09030.1 - 1.3e-71 240.8 0.0 1.6e-71 240.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM09030.1 - 4.4e-36 124.2 0.0 5.9e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM09030.1 - 1.6e-07 30.5 0.0 3.8e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.19 KFM09030.1 - 9.2e-07 29.2 0.0 9.2e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase C terminal domain Kdo PF06293.9 KFM09030.1 - 0.0018 17.3 0.0 0.0029 16.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFM09030.1 - 0.029 14.0 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PX PF00787.19 KFM09030.1 - 0.048 13.4 0.1 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 PX domain Pacs-1 PF10254.4 KFM09030.1 - 0.16 10.5 0.4 0.23 10.0 0.3 1.2 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein Sugar_tr PF00083.19 KFM09031.1 - 1.2e-98 330.7 29.7 2.2e-75 253.9 11.5 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KFM09031.1 - 3.9e-28 98.1 39.0 9.1e-26 90.3 15.2 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily TBP PF00352.16 KFM09032.1 - 2.6e-43 145.2 0.2 2.9e-21 74.6 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 KFM09032.1 - 0.00036 20.5 0.0 0.0082 16.1 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3378) HLH PF00010.21 KFM09033.1 - 9.8e-17 60.4 0.2 1.5e-16 59.8 0.1 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ribosomal_L7Ae PF01248.21 KFM09035.1 - 8.8e-31 105.2 1.9 1.1e-30 105.0 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family MFS_1 PF07690.11 KFM09036.1 - 3.1e-33 114.9 49.0 2.6e-25 88.9 25.4 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFM09036.1 - 9.4e-08 30.8 20.7 5.3e-07 28.3 6.3 2.1 1 1 1 2 2 2 2 MFS/sugar transport protein LacY_symp PF01306.14 KFM09036.1 - 0.00068 18.3 15.6 0.013 14.1 0.2 2.2 2 0 0 2 2 2 2 LacY proton/sugar symporter CN_hydrolase PF00795.17 KFM09037.1 - 1.7e-15 56.8 0.0 2.9e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CN_hydrolase PF00795.17 KFM09038.1 - 1.5e-16 60.2 0.0 2.3e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase 7tm_1 PF00001.16 KFM09039.1 - 7.1e-64 215.4 16.0 1.1e-63 214.7 11.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM09039.1 - 3.3e-06 26.4 24.3 5.7e-06 25.6 16.8 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Syntaxin_2 PF14523.1 KFM09040.1 - 1.8e-26 92.1 9.6 1.8e-26 92.1 6.7 2.3 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 KFM09040.1 - 5.9e-20 70.7 6.9 5.9e-20 70.7 4.8 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 KFM09040.1 - 1.6e-08 34.6 1.9 1.6e-08 34.6 1.3 2.4 2 1 0 2 2 2 1 Syntaxin Peptidase_M61 PF05299.7 KFM09040.1 - 0.076 12.9 0.7 11 6.0 0.0 2.6 2 1 1 3 3 3 0 M61 glycyl aminopeptidase Sec5 PF15469.1 KFM09040.1 - 0.13 11.9 4.3 0.24 11.0 0.2 2.3 2 1 0 2 2 2 0 Exocyst complex component Sec5 DUF2383 PF09537.5 KFM09040.1 - 0.23 11.7 5.6 8.1 6.7 0.2 3.4 3 2 0 3 3 3 0 Domain of unknown function (DUF2383) EAP30 PF04157.11 KFM09040.1 - 0.37 9.9 6.4 0.069 12.2 1.5 2.1 2 1 0 2 2 2 0 EAP30/Vps36 family MCPsignal PF00015.16 KFM09040.1 - 0.4 10.1 9.1 0.39 10.2 1.2 2.3 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF342 PF03961.8 KFM09040.1 - 0.94 7.8 7.3 0.38 9.1 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF342) PilJ PF13675.1 KFM09040.1 - 2.1 8.6 8.4 0.38 11.0 1.0 2.7 2 2 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Cob_adeno_trans PF01923.13 KFM09040.1 - 2.5 7.8 6.1 1.9 8.2 0.9 2.3 2 0 0 2 2 2 0 Cobalamin adenosyltransferase CCDC-167 PF15188.1 KFM09040.1 - 3 7.8 8.8 0.2 11.6 0.3 2.9 3 1 1 4 4 4 0 Coiled-coil domain-containing protein 167 GAS PF13851.1 KFM09040.1 - 3 6.9 16.7 4.3 6.4 5.3 2.7 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding NYD-SP28 PF14772.1 KFM09040.1 - 3.6 7.7 13.9 0.34 11.0 2.5 3.5 2 2 1 3 3 3 0 Sperm tail 4HB_MCP_1 PF12729.2 KFM09040.1 - 5.4 6.3 11.7 0.62 9.3 2.6 2.6 2 1 0 2 2 2 0 Four helix bundle sensory module for signal transduction DUF2203 PF09969.4 KFM09040.1 - 6.6 6.9 8.3 4.4 7.5 0.6 2.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Cu2_monooxygen PF01082.15 KFM09041.1 - 2.2e-45 153.9 1.4 2.9e-45 153.4 0.2 1.8 2 0 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Cu2_monoox_C PF03712.10 KFM09041.1 - 6.7e-36 123.0 0.1 6.2e-35 119.8 0.0 2.3 3 0 0 3 3 3 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain DOMON PF03351.12 KFM09041.1 - 2e-11 43.9 0.4 3.5e-11 43.1 0.3 1.4 1 0 0 1 1 1 1 DOMON domain Cys_knot PF00007.17 KFM09043.1 - 1.4e-16 60.4 9.9 1.4e-16 60.4 6.8 2.6 2 0 0 2 2 2 1 Cystine-knot domain TSP_1 PF00090.14 KFM09043.1 - 3.4e-10 39.8 6.3 3.4e-10 39.8 4.4 2.5 3 0 0 3 3 3 1 Thrombospondin type 1 domain Phosphodiest PF01663.17 KFM09044.1 - 2.6e-63 214.5 0.1 3.4e-63 214.1 0.1 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Somatomedin_B PF01033.12 KFM09044.1 - 4.2e-17 61.8 43.5 2.8e-09 36.7 8.9 3.0 3 0 0 3 3 3 2 Somatomedin B domain Endonuclease_NS PF01223.18 KFM09044.1 - 1.2e-14 54.4 0.2 2.2e-14 53.5 0.1 1.4 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Sulfatase PF00884.18 KFM09044.1 - 0.0027 16.9 0.0 0.84 8.7 0.0 2.3 2 0 0 2 2 2 2 Sulfatase Metalloenzyme PF01676.13 KFM09044.1 - 0.14 11.5 0.1 0.23 10.8 0.1 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily Med23 PF11573.3 KFM09046.1 - 0 1918.7 9.5 0 1918.5 6.6 1.0 1 0 0 1 1 1 1 Mediator complex subunit 23 AKAP7_NLS PF10469.4 KFM09047.1 - 1.2e-27 97.0 0.4 1.2e-27 97.0 0.2 1.3 2 0 0 2 2 2 1 AKAP7 2'5' RNA ligase-like domain AKAP7_RIRII_bdg PF10470.4 KFM09047.1 - 4.8e-26 90.3 3.4 8.6e-26 89.5 2.4 1.4 1 0 0 1 1 1 1 PKA-RI-RII subunit binding domain of A-kinase anchor protein 2_5_RNA_ligase2 PF13563.1 KFM09047.1 - 0.00027 20.7 0.1 0.0007 19.3 0.0 1.6 2 0 0 2 2 2 1 2'-5' RNA ligase superfamily Corona_NS2A PF05213.7 KFM09047.1 - 0.011 15.0 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 0 Coronavirus NS2A protein MutS_V PF00488.16 KFM09048.1 - 4.7e-66 222.5 0.0 7.3e-66 221.9 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KFM09048.1 - 1.7e-29 103.0 0.4 2.8e-29 102.3 0.3 1.4 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 KFM09048.1 - 3.5e-13 49.5 0.0 7.2e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_14 PF13173.1 KFM09048.1 - 0.03 14.2 0.0 0.11 12.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain 4_1_CTD PF05902.8 KFM09049.1 - 5.7e-34 116.5 6.5 5.7e-34 116.5 4.5 3.4 3 1 0 3 3 3 1 4.1 protein C-terminal domain (CTD) SAB PF04382.8 KFM09049.1 - 3.2e-27 93.9 1.9 1e-26 92.3 1.3 2.0 1 0 0 1 1 1 1 SAB domain FERM_C PF09380.5 KFM09049.1 - 1.8e-23 82.5 0.1 6e-23 80.8 0.0 1.9 2 0 0 2 2 2 1 FERM C-terminal PH-like domain FERM_N PF09379.5 KFM09049.1 - 2.6e-22 78.6 0.6 1.5e-21 76.2 0.2 2.5 2 0 0 2 2 2 1 FERM N-terminal domain FERM_M PF00373.13 KFM09049.1 - 1.1e-19 70.8 0.1 1.1e-19 70.8 0.1 3.3 3 1 0 3 3 3 1 FERM central domain FA PF08736.6 KFM09049.1 - 3.7e-18 65.0 2.0 1.5e-17 63.0 1.4 2.2 1 0 0 1 1 1 1 FERM adjacent (FA) DUF2371 PF10177.4 KFM09050.1 - 5.5e-57 191.5 0.0 4.9e-56 188.5 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2371) She9_MDM33 PF05546.6 KFM09050.1 - 0.023 14.2 0.0 0.083 12.4 0.0 1.8 1 1 1 2 2 2 0 She9 / Mdm33 family RbcS PF12338.3 KFM09050.1 - 0.035 13.8 0.3 0.11 12.2 0.2 1.8 1 0 0 1 1 1 0 Ribulose-1,5-bisphosphate carboxylase small subunit SAM_1 PF00536.25 KFM09051.1 - 2.7e-11 43.4 0.3 9.4e-11 41.7 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFM09051.1 - 3.4e-09 36.4 0.3 1.7e-08 34.1 0.0 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) MBT PF02820.13 KFM09052.1 - 4e-97 318.2 4.9 1.7e-33 114.3 0.0 3.1 3 0 0 3 3 3 3 mbt repeat Tudor-knot PF11717.3 KFM09052.1 - 0.45 10.2 6.4 1.8 8.3 0.0 3.0 3 0 0 3 3 3 0 RNA binding activity-knot of a chromodomain SYS1 PF09801.4 KFM09053.1 - 9.2e-07 28.9 17.1 1.4e-06 28.3 11.9 1.2 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network RhoGAP PF00620.22 KFM09054.1 - 1.2e-41 141.8 1.7 1.2e-41 141.8 1.1 2.3 2 0 0 2 2 2 1 RhoGAP domain FTO_CTD PF12934.2 KFM09054.1 - 0.01 15.4 1.0 0.01 15.4 0.7 2.1 2 0 0 2 2 2 1 FTO C-terminal domain PAPA-1 PF04795.7 KFM09054.1 - 0.022 15.4 4.9 0.022 15.4 3.4 2.4 2 0 0 2 2 2 0 PAPA-1-like conserved region BPL_N PF09825.4 KFM09054.1 - 0.043 12.6 3.9 0.028 13.1 0.3 2.0 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal Laminin_G_1 PF00054.18 KFM09056.1 - 4e-08 33.3 0.0 6e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_2 PF02210.19 KFM09056.1 - 0.0001 22.3 0.0 0.00016 21.6 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain Mito_fiss_reg PF05308.6 KFM09056.1 - 0.42 9.9 6.3 0.55 9.5 4.4 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Laminin_I PF06008.9 KFM09057.1 - 2e-51 174.8 14.9 2.2e-51 174.7 10.3 1.0 1 0 0 1 1 1 1 Laminin Domain I Cytochrom_C_2 PF01322.15 KFM09057.1 - 0.0086 16.6 5.4 0.049 14.1 0.2 2.4 1 1 1 2 2 2 1 Cytochrome C' DUF1978 PF09321.5 KFM09057.1 - 0.024 14.0 12.1 0.049 13.0 8.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1978) Hormone_1 PF00103.15 KFM09057.1 - 0.11 11.8 3.3 4.4 6.5 0.9 2.2 1 1 1 2 2 2 0 Somatotropin hormone family DUF948 PF06103.6 KFM09057.1 - 0.13 12.0 8.1 0.27 11.1 0.6 3.1 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Lipoprotein_6 PF01441.14 KFM09057.1 - 0.21 11.3 8.6 0.46 10.3 5.3 1.8 1 1 1 2 2 2 0 Lipoprotein Pex19 PF04614.7 KFM09057.1 - 0.28 10.7 9.3 0.37 10.3 6.5 1.3 1 0 0 1 1 1 0 Pex19 protein family TIP120 PF08623.5 KFM09057.1 - 0.43 10.1 4.2 0.19 11.2 0.5 2.0 1 1 1 2 2 2 0 TATA-binding protein interacting (TIP20) ADIP PF11559.3 KFM09057.1 - 0.57 10.0 15.6 0.23 11.3 7.7 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Ferritin PF00210.19 KFM09057.1 - 0.67 9.7 7.2 0.28 10.9 0.4 2.4 1 1 1 2 2 2 0 Ferritin-like domain zf-ZPR1 PF03367.8 KFM09057.1 - 0.72 8.9 4.8 1.8 7.6 0.5 2.2 1 1 1 2 2 2 0 ZPR1 zinc-finger domain Toxin_52 PF15605.1 KFM09057.1 - 0.75 9.7 8.0 7.8 6.4 0.9 3.4 1 1 3 4 4 4 0 Putative toxin 52 YlqD PF11068.3 KFM09057.1 - 0.77 9.7 11.9 0.089 12.8 3.3 2.4 1 1 1 2 2 2 0 YlqD protein Astro_capsid PF03115.9 KFM09057.1 - 1.1 7.4 5.6 1.2 7.3 3.9 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor HisKA_3 PF07730.8 KFM09057.1 - 2.2 8.7 12.4 3.7 7.9 0.7 4.1 2 1 2 4 4 4 0 Histidine kinase DUF1664 PF07889.7 KFM09057.1 - 2.2 8.0 6.4 16 5.2 0.2 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) APG6 PF04111.7 KFM09057.1 - 3.1 6.7 14.6 5.2 6.0 9.5 1.7 1 1 1 2 2 2 0 Autophagy protein Apg6 Laminin_II PF06009.7 KFM09057.1 - 3.6 7.3 12.0 7 6.4 1.4 3.0 1 1 2 3 3 3 0 Laminin Domain II Acyl-CoA_dh_C PF12806.2 KFM09057.1 - 5.1 6.9 6.5 5.1 6.9 1.0 2.8 1 1 1 3 3 3 0 Acetyl-CoA dehydrogenase C-terminal like Syntaxin PF00804.20 KFM09057.1 - 8.4 6.6 11.8 4.5 7.5 2.3 2.8 1 1 2 3 3 3 0 Syntaxin Laminin_N PF00055.12 KFM09058.1 - 3.6e-88 294.5 0.1 3.6e-88 294.5 0.0 1.7 2 0 0 2 2 2 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.19 KFM09058.1 - 1.9e-50 168.5 142.9 3.6e-10 39.6 6.8 8.9 9 0 0 9 9 9 8 Laminin EGF-like (Domains III and V) Laminin_B PF00052.13 KFM09058.1 - 1.9e-28 98.7 0.0 2.7e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 Laminin B (Domain IV) Aa_trans PF01490.13 KFM09059.1 - 1.8e-71 240.7 27.9 2.1e-71 240.6 19.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Kua-UEV1_localn PF10520.4 KFM09059.1 - 0.31 10.6 5.5 0.24 11.0 2.2 2.0 1 1 1 2 2 2 0 Kua-ubiquitin conjugating enzyme hybrid localisation domain Y_phosphatase PF00102.22 KFM09060.1 - 3.3e-156 517.5 0.2 3.9e-89 298.0 0.0 2.4 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.16 KFM09060.1 - 1.2e-24 86.1 0.5 4.1e-10 39.6 0.0 5.2 5 0 0 5 5 5 2 Fibronectin type III domain MAM PF00629.18 KFM09060.1 - 2.5e-22 79.3 0.0 5.1e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 MAM domain DSPc PF00782.15 KFM09060.1 - 6.5e-09 35.4 1.3 0.002 17.7 0.1 2.6 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Ig_2 PF13895.1 KFM09060.1 - 1.6e-07 31.2 0.0 4.3e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 KFM09060.1 - 4.1e-07 29.7 0.0 1e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin I-set domain Y_phosphatase3 PF13350.1 KFM09060.1 - 8.5e-06 26.1 0.0 0.07 13.3 0.0 2.8 3 0 0 3 3 3 2 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KFM09060.1 - 0.0011 18.9 0.2 0.15 12.1 0.0 2.9 3 0 0 3 3 3 1 Inositol hexakisphosphate Ly49 PF08391.5 KFM09060.1 - 0.0044 17.1 0.1 0.32 11.1 0.1 2.5 2 0 0 2 2 2 1 Ly49-like protein, N-terminal region EphA2_TM PF14575.1 KFM09060.1 - 0.011 16.0 0.0 0.027 14.8 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain V-set PF07686.12 KFM09060.1 - 0.026 14.4 0.1 0.13 12.1 0.0 2.0 1 1 0 1 1 1 0 Immunoglobulin V-set domain Lep_receptor_Ig PF06328.6 KFM09060.1 - 0.057 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Ig-like C2-type domain Protocadherin PF08374.6 KFM09060.1 - 0.32 10.5 1.9 0.33 10.5 0.2 1.7 2 0 0 2 2 2 0 Protocadherin CABIT PF12736.2 KFM09061.1 - 4.3e-91 304.4 5.5 3.9e-51 173.5 2.0 2.2 2 0 0 2 2 2 2 Cell-cycle sustaining, positive selection, DUF1966 PF09260.6 KFM09061.1 - 0.0063 16.5 0.0 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) DUF781 PF05612.7 KFM09062.1 - 4.9e-110 367.5 0.1 5.8e-110 367.3 0.0 1.0 1 0 0 1 1 1 1 Mouse protein of unknown function (DUF781) DUF3166 PF11365.3 KFM09063.1 - 2.8e-68 226.4 38.2 3e-43 146.1 1.3 4.9 4 1 1 5 5 5 2 Protein of unknown function (DUF3166) DUF2968 PF11180.3 KFM09063.1 - 0.00017 21.0 7.2 0.00017 21.0 5.0 3.6 4 1 0 4 4 4 1 Protein of unknown function (DUF2968) TSC22 PF01166.13 KFM09063.1 - 0.0027 17.6 39.2 0.0038 17.1 0.2 7.1 7 1 0 7 7 7 3 TSC-22/dip/bun family Halo_GVPC PF05465.8 KFM09063.1 - 0.047 13.6 0.5 0.14 12.1 0.4 1.9 1 0 0 1 1 1 0 Halobacterial gas vesicle protein C (GVPC) repeat DUF2207 PF09972.4 KFM09063.1 - 0.065 11.8 0.1 0.065 11.8 0.1 2.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Fes1 PF08609.5 KFM09063.1 - 0.65 10.5 8.0 1.6 9.2 3.8 2.9 2 1 0 2 2 2 0 Nucleotide exchange factor Fes1 APG6 PF04111.7 KFM09063.1 - 3.1 6.7 50.5 0.55 9.2 0.0 4.2 1 1 3 4 4 4 0 Autophagy protein Apg6 DUF972 PF06156.8 KFM09063.1 - 7 7.0 48.7 1.1 9.6 5.7 6.6 3 2 4 7 7 7 0 Protein of unknown function (DUF972) DUF4482 PF14818.1 KFM09064.1 - 2e-36 125.7 14.5 2e-36 125.7 10.1 4.3 3 1 2 5 5 5 2 Domain of unknown function (DUF4482) WWE PF02825.15 KFM09065.1 - 1.9e-13 49.6 0.9 3.6e-13 48.7 0.6 1.4 1 0 0 1 1 1 1 WWE domain zf-RING_2 PF13639.1 KFM09065.1 - 2.9e-06 26.9 11.8 5.7e-06 26.0 8.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFM09065.1 - 6.6e-06 25.7 10.2 1.1e-05 24.9 7.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM09065.1 - 1.4e-05 24.5 9.4 3.6e-05 23.3 6.6 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM09065.1 - 5.4e-05 23.1 13.2 9.4e-05 22.3 9.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM09065.1 - 0.0069 16.0 11.4 0.012 15.2 7.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFM09065.1 - 0.013 15.3 10.7 0.013 15.3 7.4 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KFM09065.1 - 0.077 12.7 9.0 0.17 11.6 6.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.1 KFM09065.1 - 1 9.1 7.0 2.1 8.2 4.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Autophagy_act_C PF03987.10 KFM09066.1 - 5.3e-22 77.7 0.3 1.1e-21 76.8 0.2 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Ribosom_S12_S23 PF00164.20 KFM09067.1 - 9e-32 109.0 0.3 9.9e-32 108.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 ATP-synt_S1 PF05827.7 KFM09068.1 - 2.4e-09 36.9 0.2 3e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Lamp PF01299.12 KFM09068.1 - 1.7e-06 27.3 0.2 2.1e-06 27.1 0.1 1.1 1 0 0 1 1 1 1 Lysosome-associated membrane glycoprotein (Lamp) Yae1_N PF09811.4 KFM09069.1 - 3.2e-18 64.9 55.7 1.5e+04 -16.7 38.6 5.2 1 1 0 1 1 1 0 Essential protein Yae1, N terminal DUF1242 PF06842.7 KFM09070.1 - 3.5e-16 58.4 1.9 4e-16 58.2 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) ATP-synt_8 PF00895.15 KFM09070.1 - 0.039 14.1 0.1 0.039 14.1 0.1 1.0 1 0 0 1 1 1 0 ATP synthase protein 8 LST1 PF05083.8 KFM09070.1 - 0.14 12.1 0.3 0.14 12.1 0.2 1.1 1 0 0 1 1 1 0 LST-1 protein XRCC4 PF06632.7 KFM09071.1 - 5.8e-102 341.0 9.0 2.5e-96 322.5 2.6 2.0 2 0 0 2 2 2 2 DNA double-strand break repair and V(D)J recombination protein XRCC4 RHH_2 PF03693.9 KFM09071.1 - 0.036 14.2 0.2 2.1 8.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0156) GNT-I PF03071.10 KFM09071.1 - 0.1 11.0 0.2 2.1 6.8 0.0 2.0 2 0 0 2 2 2 0 GNT-I family DivIVA PF05103.8 KFM09071.1 - 8.8 6.3 8.8 13 5.8 2.7 2.4 2 1 0 2 2 2 0 DivIVA protein Xlink PF00193.12 KFM09072.1 - 4.1e-72 238.3 0.4 1.7e-36 124.1 0.0 2.2 2 0 0 2 2 2 2 Extracellular link domain V-set PF07686.12 KFM09072.1 - 1.8e-12 47.1 0.0 3.3e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 KFM09072.1 - 5.1e-05 23.0 0.0 0.00012 21.8 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin I-set domain Foamy_BEL PF03274.9 KFM09072.1 - 0.00043 19.5 0.0 0.0007 18.8 0.0 1.3 1 0 0 1 1 1 1 Foamy virus BEL 1/2 protein Ig_2 PF13895.1 KFM09072.1 - 0.0025 17.8 0.0 0.0059 16.6 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin domain F5_F8_type_C PF00754.20 KFM09073.1 - 6.3e-65 216.8 6.6 6.7e-34 116.5 0.5 2.1 2 0 0 2 2 2 2 F5/8 type C domain EGF PF00008.22 KFM09073.1 - 1.1e-20 73.2 40.7 2e-08 34.0 5.3 3.6 3 0 0 3 3 3 3 EGF-like domain EGF_2 PF07974.8 KFM09073.1 - 2.6e-05 24.3 39.3 0.011 15.8 4.9 3.8 3 0 0 3 3 3 2 EGF-like domain hEGF PF12661.2 KFM09073.1 - 0.0022 17.9 18.8 0.02 14.9 1.1 4.0 3 0 0 3 3 3 2 Human growth factor-like EGF DUF1438 PF07270.6 KFM09073.1 - 0.036 13.9 0.1 13 5.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1438) DUF4050 PF13259.1 KFM09075.1 - 0.079 12.8 0.3 0.14 12.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) RVT_1 PF00078.22 KFM09076.1 - 0.023 14.0 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Ras PF00071.17 KFM09077.1 - 2.4e-50 170.0 0.0 2.7e-50 169.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM09077.1 - 4.8e-13 49.6 0.0 6.5e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM09077.1 - 2.2e-05 23.7 0.0 2.7e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFM09077.1 - 0.026 13.9 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Lipase_3 PF01764.20 KFM09078.1 - 2e-16 59.9 0.0 3.2e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KFM09078.1 - 0.026 14.2 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFM09078.1 - 0.044 13.6 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family AXE1 PF05448.7 KFM09078.1 - 0.048 12.1 0.0 0.074 11.5 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Esterase PF00756.15 KFM09078.1 - 0.22 10.8 0.0 0.45 9.9 0.0 1.4 1 0 0 1 1 1 0 Putative esterase ER_lumen_recept PF00810.13 KFM09079.1 - 1e-44 152.5 4.6 1.7e-44 151.9 3.2 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 KFM09079.1 - 0.023 14.2 1.4 0.023 14.2 0.9 2.3 2 1 1 3 3 3 0 PQ loop repeat DREV PF05219.7 KFM09080.1 - 3e-136 452.4 0.0 3.4e-136 452.3 0.0 1.0 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_23 PF13489.1 KFM09080.1 - 7.4e-12 45.2 0.0 1.4e-11 44.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFM09080.1 - 1e-08 35.5 0.0 1.6e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFM09080.1 - 3.4e-06 27.4 0.0 5.8e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFM09080.1 - 8.4e-06 25.4 0.0 1.4e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFM09080.1 - 6.5e-05 23.4 0.0 0.00031 21.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 KFM09080.1 - 0.0039 16.2 0.0 0.0071 15.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.9 KFM09080.1 - 0.041 13.2 0.0 0.98 8.7 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_PK PF05891.7 KFM09080.1 - 0.064 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase V-set PF07686.12 KFM09081.1 - 9.1e-08 32.0 0.4 1.9e-07 30.9 0.3 1.6 1 1 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 KFM09081.1 - 0.013 15.3 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin I-set domain Ig_3 PF13927.1 KFM09081.1 - 0.048 14.1 1.4 0.12 12.9 1.0 1.7 1 1 0 1 1 1 0 Immunoglobulin domain ig PF00047.20 KFM09081.1 - 0.11 12.6 1.5 0.67 10.1 1.0 2.3 1 1 0 1 1 1 0 Immunoglobulin domain MFS_2 PF13347.1 KFM09082.1 - 4.3e-37 127.5 24.4 5.8e-37 127.1 16.9 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein BLOC1_2 PF10046.4 KFM09083.1 - 0.004 17.2 10.3 0.004 17.2 7.1 4.5 4 2 1 5 5 5 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 CCDC155 PF14662.1 KFM09083.1 - 0.0054 16.3 19.2 0.0054 16.3 13.3 3.1 2 1 0 3 3 3 1 Coiled-coil region of CCDC155 Reo_sigmaC PF04582.7 KFM09083.1 - 0.0085 15.3 2.4 0.0085 15.3 1.7 2.3 2 0 0 2 2 2 1 Reovirus sigma C capsid protein DUF3450 PF11932.3 KFM09083.1 - 0.0099 15.1 3.5 0.0099 15.1 2.4 3.9 3 1 1 4 4 4 2 Protein of unknown function (DUF3450) M_domain PF12938.2 KFM09083.1 - 0.96 9.2 8.9 0.73 9.6 4.1 2.3 2 1 0 2 2 2 0 M domain of GW182 Baculo_IE-1 PF05290.6 KFM09083.1 - 3.4 7.4 9.1 8 6.1 0.5 3.3 3 1 0 3 3 3 0 Baculovirus immediate-early protein (IE-0) NPV_P10 PF05531.7 KFM09083.1 - 4 7.7 14.2 1.7 8.9 0.0 4.2 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein FUSC PF04632.7 KFM09083.1 - 4.5 5.5 4.9 7.3 4.8 3.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1664 PF07889.7 KFM09083.1 - 8.5 6.2 19.3 2 8.1 4.3 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Sin_N PF04801.8 KFM09084.1 - 8.8e-163 542.0 3.0 8.8e-163 542.0 2.1 1.7 3 0 0 3 3 3 1 Sin-like protein conserved region Alpha_kinase PF02816.13 KFM09085.1 - 2.9e-56 190.1 0.2 4.7e-56 189.4 0.1 1.3 1 0 0 1 1 1 1 Alpha-kinase family Sel1 PF08238.7 KFM09085.1 - 8.6e-06 26.2 9.6 0.95 10.1 0.1 5.0 5 0 0 5 5 5 3 Sel1 repeat 3Beta_HSD PF01073.14 KFM09086.1 - 8.2e-66 221.5 0.0 1.1e-65 221.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KFM09086.1 - 1.8e-27 96.3 0.0 2.2e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KFM09086.1 - 7.9e-11 41.3 0.0 1e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KFM09086.1 - 1.2e-09 37.4 0.0 2.1e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KFM09086.1 - 2.4e-08 34.1 0.0 3.3e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KFM09086.1 - 2.7e-08 33.0 0.5 1.2e-07 31.0 0.3 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 KFM09086.1 - 0.00022 20.5 0.0 0.00058 19.1 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 KFM09086.1 - 0.023 14.6 0.3 0.068 13.0 0.2 1.7 1 1 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.14 KFM09087.1 - 8e-61 205.1 0.0 1e-60 204.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KFM09087.1 - 1.7e-24 86.5 0.0 2.2e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KFM09087.1 - 1.8e-11 43.4 0.0 2.7e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 KFM09087.1 - 1.4e-07 30.7 0.0 3.2e-07 29.5 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KFM09087.1 - 3.6e-06 26.0 0.0 4.8e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KFM09087.1 - 1.5e-05 25.0 0.0 2.1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Bac_Ubq_Cox PF01654.12 KFM09088.1 - 1.2e-05 23.9 3.1 1.3e-05 23.7 2.2 1.1 1 0 0 1 1 1 1 Bacterial Cytochrome Ubiquinol Oxidase Claudin_2 PF13903.1 KFM09088.1 - 0.00016 21.4 4.7 0.00034 20.3 3.3 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction TauE PF01925.14 KFM09088.1 - 0.038 13.4 5.3 0.046 13.1 3.7 1.1 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE L_HGMIC_fpl PF10242.4 KFM09088.1 - 0.055 13.4 5.3 0.093 12.7 3.5 1.6 1 1 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein DUF998 PF06197.8 KFM09088.1 - 0.089 12.1 9.1 0.21 10.8 6.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF998) Tetraspannin PF00335.15 KFM09088.1 - 0.17 11.1 7.6 0.22 10.7 0.1 2.0 2 0 0 2 2 2 0 Tetraspanin family SLAC1 PF03595.12 KFM09088.1 - 0.19 10.3 10.6 1.1 7.8 7.3 1.9 1 1 0 1 1 1 0 Voltage-dependent anion channel HlyIII PF03006.15 KFM09088.1 - 0.21 11.0 5.8 0.054 12.9 1.5 1.6 1 1 0 1 1 1 0 Haemolysin-III related DUF456 PF04306.8 KFM09088.1 - 0.24 11.4 8.9 0.12 12.4 3.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF456) DUF2269 PF10027.4 KFM09088.1 - 0.56 9.9 4.8 0.99 9.1 3.3 1.4 1 1 0 1 1 1 0 Predicted integral membrane protein (DUF2269) 7TMR-DISM_7TM PF07695.6 KFM09088.1 - 1.7 8.2 13.0 4.4 6.9 8.2 1.8 1 1 1 2 2 2 0 7TM diverse intracellular signalling DUF4131 PF13567.1 KFM09088.1 - 2.3 7.5 7.2 0.78 9.1 2.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF423 PF04241.10 KFM09088.1 - 3 7.8 6.3 0.36 10.7 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF423) DUF1218 PF06749.7 KFM09088.1 - 4.3 7.8 6.9 1.7 9.1 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) DUF202 PF02656.10 KFM09088.1 - 6.6 7.0 8.9 5.4e+02 0.9 6.2 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF2975 PF11188.3 KFM09088.1 - 7.1 6.3 7.9 20 4.9 5.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) DUF2721 PF11026.3 KFM09088.1 - 7.4 6.2 10.3 3.8 7.1 3.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Peptidase_M16 PF00675.15 KFM09089.1 - 8.1e-32 110.0 0.0 1.4e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KFM09089.1 - 2.2e-24 86.1 0.2 9.9e-24 84.0 0.0 2.0 3 0 0 3 3 3 1 Peptidase M16 inactive domain OCD_Mu_crystall PF02423.10 KFM09090.1 - 2e-89 299.4 0.7 2.2e-89 299.3 0.5 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 KFM09090.1 - 9.3e-09 35.4 0.0 1.4e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.10 KFM09090.1 - 0.00011 22.0 0.7 0.00054 19.8 0.3 2.2 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KFM09090.1 - 0.00018 21.8 0.0 0.00051 20.4 0.0 1.8 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Ank_2 PF12796.2 KFM09091.1 - 2.7e-21 75.7 0.7 1.8e-17 63.4 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFM09091.1 - 5.8e-18 64.5 1.2 1.6e-10 40.8 0.2 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 KFM09091.1 - 1.3e-17 62.6 1.7 2.3e-10 39.7 0.3 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 KFM09091.1 - 6.4e-16 58.3 1.4 5e-08 33.2 0.2 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM09091.1 - 1.9e-13 49.1 0.7 1.1e-06 28.2 0.2 4.6 4 0 0 4 4 4 2 Ankyrin repeat SAM_1 PF00536.25 KFM09091.1 - 9.5e-07 28.9 0.0 2.2e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ribosomal_S18 PF01084.15 KFM09091.1 - 0.0024 17.6 0.2 0.0071 16.1 0.1 1.8 1 0 0 1 1 1 1 Ribosomal protein S18 Zona_pellucida PF00100.18 KFM09092.1 - 3e-51 174.3 0.3 1e-50 172.6 0.0 2.0 2 0 0 2 2 2 1 Zona pellucida-like domain CcmH PF03918.9 KFM09093.1 - 0.0023 16.9 0.0 0.0049 15.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome C biogenesis protein Complex1_LYR PF05347.10 KFM09094.1 - 1.4e-18 66.4 0.1 2.5e-18 65.6 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KFM09094.1 - 2.5e-14 53.2 0.1 4e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 KFM09094.1 - 0.037 14.4 0.5 0.052 14.0 0.1 1.4 2 0 0 2 2 2 0 Complex1_LYR-like Cullin_binding PF03556.10 KFM09095.1 - 8.8e-36 122.5 0.1 1.5e-35 121.8 0.1 1.4 1 0 0 1 1 1 1 Cullin binding RNase_T PF00929.19 KFM09096.1 - 3.5e-21 76.1 0.0 8.8e-21 74.8 0.0 1.7 1 0 0 1 1 1 1 Exonuclease RRM_1 PF00076.17 KFM09096.1 - 7.2e-19 67.1 0.0 5.3e-11 41.9 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM09096.1 - 3e-10 39.9 0.0 1.1e-05 25.3 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM09096.1 - 4.9e-07 29.5 0.0 0.00029 20.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TMF_DNA_bd PF12329.3 KFM09096.1 - 0.00061 19.5 2.8 0.0022 17.7 1.9 1.9 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding EzrA PF06160.7 KFM09096.1 - 0.064 11.4 0.1 0.12 10.5 0.1 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA RNase_T PF00929.19 KFM09097.1 - 3.2e-21 76.3 0.0 5.3e-21 75.5 0.0 1.3 1 1 0 1 1 1 1 Exonuclease Tnp_DNA_bind PF14706.1 KFM09097.1 - 0.18 11.5 0.6 1.7 8.4 0.0 2.2 2 0 0 2 2 2 0 Transposase DNA-binding AMP-binding PF00501.23 KFM09098.1 - 1.5e-86 290.3 0.0 2e-86 290.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFM09098.1 - 2.1e-20 73.4 0.8 3.8e-20 72.6 0.6 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain THUMP PF02926.12 KFM09099.1 - 6.5e-23 81.2 1.5 1.3e-22 80.2 0.9 1.7 1 1 0 1 1 1 1 THUMP domain DUF1796 PF08795.5 KFM09099.1 - 0.0067 16.0 0.2 0.013 15.0 0.2 1.5 1 0 0 1 1 1 1 Putative papain-like cysteine peptidase (DUF1796) RNase_P_Rpp14 PF01900.14 KFM09099.1 - 0.02 14.7 0.1 0.067 13.1 0.0 1.9 2 0 0 2 2 2 0 Rpp14/Pop5 family VHL PF01847.11 KFM09099.1 - 0.045 13.3 0.2 0.069 12.7 0.2 1.3 1 0 0 1 1 1 0 von Hippel-Lindau disease tumour suppressor protein AMP-binding PF00501.23 KFM09100.1 - 3.9e-84 282.4 0.0 4.8e-84 282.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFM09100.1 - 3.5e-21 75.9 0.5 6.6e-21 75.0 0.3 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 7tm_1 PF00001.16 KFM09101.1 - 1.3e-25 90.0 28.0 1.6e-25 89.6 19.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.4 KFM09101.1 - 1.3e-09 37.6 28.9 3e-06 26.5 8.6 2.2 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw SMAP PF15477.1 KFM09102.1 - 6.6e-18 64.7 3.2 6.6e-18 64.7 2.2 2.3 2 0 0 2 2 2 1 Small acidic protein family DUF3895 PF13034.1 KFM09103.1 - 0.047 13.1 0.1 0.21 11.1 0.1 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3895) SR-25 PF10500.4 KFM09103.1 - 0.12 11.8 3.2 0.27 10.6 2.2 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein GDPD PF03009.12 KFM09105.1 - 4e-24 85.4 0.1 9.5e-24 84.2 0.0 1.6 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family TMC PF07810.8 KFM09106.1 - 9.2e-39 132.2 0.8 9.2e-39 132.2 0.5 3.2 3 1 1 4 4 4 1 TMC domain TMC PF07810.8 KFM09108.1 - 8.1e-45 151.7 0.4 8.1e-45 151.7 0.3 2.4 2 0 0 2 2 2 1 TMC domain COQ7 PF03232.8 KFM09109.1 - 2.2e-78 261.6 0.0 2.5e-78 261.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 KFM09109.1 - 0.0042 17.3 0.2 0.43 10.8 0.0 2.1 2 0 0 2 2 2 1 Rubrerythrin PAH PF02671.16 KFM09109.1 - 0.063 12.9 0.1 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 Paired amphipathic helix repeat DUF4546 PF15079.1 KFM09109.1 - 0.073 12.2 0.1 0.073 12.2 0.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4546) Mab-21 PF03281.9 KFM09110.1 - 1.3e-14 54.0 0.8 2.1e-14 53.3 0.6 1.4 1 1 0 1 1 1 1 Mab-21 protein C2 PF00168.25 KFM09111.1 - 2.8e-40 136.0 0.1 7.8e-19 67.3 0.0 2.3 2 0 0 2 2 2 2 C2 domain DOCK-C2 PF14429.1 KFM09111.1 - 0.0018 17.9 0.7 0.07 12.7 0.1 2.6 1 1 1 2 2 2 2 C2 domain in Dock180 and Zizimin proteins Lectin_C PF00059.16 KFM09112.1 - 5.6e-19 68.7 0.4 6.9e-19 68.4 0.3 1.1 1 0 0 1 1 1 1 Lectin C-type domain PI3_PI4_kinase PF00454.22 KFM09113.1 - 3.6e-52 177.1 0.0 9.4e-52 175.8 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 KFM09113.1 - 2.6e-12 45.9 0.1 1.1e-11 43.9 0.0 2.2 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 KFM09113.1 - 0.022 14.8 0.9 0.14 12.2 0.0 3.1 2 0 0 2 2 2 0 HEAT repeat Reticulon PF02453.12 KFM09114.1 - 5.8e-30 104.1 3.3 6.7e-30 103.9 2.3 1.0 1 0 0 1 1 1 1 Reticulon DUF106 PF01956.11 KFM09114.1 - 0.041 13.4 0.6 0.075 12.5 0.5 1.4 1 0 0 1 1 1 0 Integral membrane protein DUF106 Ribosomal_S8 PF00410.14 KFM09115.1 - 1.7e-26 92.5 0.0 2.2e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Xylo_C PF12529.3 KFM09116.1 - 2.7e-69 232.0 0.0 4.6e-69 231.3 0.0 1.4 1 0 0 1 1 1 1 Xylosyltransferase C terminal Branch PF02485.16 KFM09116.1 - 3e-48 164.1 1.9 4.8e-48 163.4 1.3 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme CarboxypepD_reg PF13620.1 KFM09117.1 - 1.6e-47 159.4 4.9 5.6e-10 39.1 0.3 9.7 9 1 0 9 9 9 7 Carboxypeptidase regulatory-like domain Cna_B PF05738.8 KFM09117.1 - 8.1e-24 83.1 4.7 0.00094 18.8 0.0 9.0 9 0 0 9 9 9 4 Cna protein B-type domain DUF4480 PF13715.1 KFM09117.1 - 1.3e-23 82.8 6.6 2.3e-06 27.5 0.2 9.1 6 1 3 9 9 9 5 Domain of unknown function (DUF4480) DUF2012 PF09430.5 KFM09117.1 - 5.3e-23 81.1 0.6 1.5e-07 31.2 0.0 7.7 7 1 1 8 8 8 4 Protein of unknown function (DUF2012) fn3_3 PF14686.1 KFM09117.1 - 8.4e-14 51.4 0.0 0.014 15.5 0.0 8.0 9 0 0 9 9 8 2 Polysaccharide lyase family 4, domain II Y_Y_Y PF07495.8 KFM09117.1 - 3.8e-06 26.5 0.5 1.2 8.9 0.0 5.2 5 0 0 5 5 5 1 Y_Y_Y domain DUF1416 PF07210.7 KFM09117.1 - 2.8e-05 23.6 0.5 4.1 7.0 0.0 5.9 6 1 1 7 7 7 1 Protein of unknown function (DUF1416) DUF2141 PF09912.4 KFM09117.1 - 0.0028 17.3 0.0 4.5 6.9 0.0 4.6 6 0 0 6 6 6 1 Uncharacterized protein conserved in bacteria (DUF2141) phage_tail_N PF08400.5 KFM09117.1 - 0.0029 17.2 0.4 6.5 6.4 0.0 5.1 6 0 0 6 6 6 1 Prophage tail fibre N-terminal DUF2846 PF11008.3 KFM09117.1 - 0.0058 16.4 0.3 51 3.7 0.0 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF2846) DUF3244 PF11589.3 KFM09117.1 - 0.012 15.2 0.3 41 3.9 0.0 5.0 5 0 0 5 5 5 0 Domain of unknown function (DUF3244) DUF3823 PF12866.2 KFM09117.1 - 0.019 14.5 0.0 1.4 8.3 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3823) Cupredoxin_1 PF13473.1 KFM09117.1 - 0.085 12.7 0.0 2.2 8.1 0.0 3.3 2 1 1 3 3 3 0 Cupredoxin-like domain ABC_membrane PF00664.18 KFM09118.1 - 3.5e-70 236.5 36.1 2.2e-40 138.8 12.9 3.4 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFM09118.1 - 1e-52 178.0 0.3 1.2e-29 103.3 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KFM09118.1 - 7e-10 38.5 0.0 2.7e-05 23.4 0.0 3.5 1 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KFM09118.1 - 1.4e-05 25.1 2.7 0.0091 15.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 KFM09118.1 - 2e-05 24.7 0.3 1.3 8.9 0.0 4.2 3 1 0 4 4 4 1 AAA domain AAA_29 PF13555.1 KFM09118.1 - 2e-05 24.0 0.7 0.17 11.4 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 KFM09118.1 - 2.4e-05 23.3 0.0 0.12 11.2 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.18 KFM09118.1 - 3.3e-05 23.8 0.0 0.085 12.8 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.1 KFM09118.1 - 6e-05 23.1 1.2 0.14 12.3 0.3 3.0 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KFM09118.1 - 8.8e-05 21.9 0.4 0.067 12.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 KFM09118.1 - 0.00019 21.3 1.5 0.0046 16.7 0.0 3.2 3 0 0 3 3 3 1 Dynamin family Zeta_toxin PF06414.7 KFM09118.1 - 0.00021 20.4 1.0 0.022 13.8 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin DUF258 PF03193.11 KFM09118.1 - 0.00041 19.5 0.1 0.053 12.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 KFM09118.1 - 0.00044 21.0 1.4 0.27 12.0 0.8 3.0 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 KFM09118.1 - 0.00049 20.5 0.5 0.15 12.6 0.0 3.1 3 0 0 3 3 2 1 Miro-like protein ABC_ATPase PF09818.4 KFM09118.1 - 0.0014 17.2 0.4 0.33 9.4 0.0 3.3 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_18 PF13238.1 KFM09118.1 - 0.0059 16.9 0.2 0.26 11.5 0.2 2.5 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 KFM09118.1 - 0.0067 15.2 0.3 0.92 8.2 0.1 2.4 2 0 0 2 2 2 1 ArgK protein AAA_23 PF13476.1 KFM09118.1 - 0.013 15.8 2.4 2.6 8.3 0.0 3.0 3 0 0 3 3 2 0 AAA domain MobB PF03205.9 KFM09118.1 - 0.047 13.3 1.6 5.3 6.7 0.1 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 KFM09118.1 - 0.059 12.9 1.7 11 5.5 0.1 2.7 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.10 KFM09118.1 - 0.07 12.8 0.9 1.2 8.8 0.1 2.4 2 0 0 2 2 2 0 NTPase AAA_10 PF12846.2 KFM09118.1 - 0.095 12.1 1.1 9 5.6 0.1 2.8 3 0 0 3 3 3 0 AAA-like domain GTP_EFTU PF00009.22 KFM09118.1 - 0.16 11.4 0.1 3.4 7.0 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain cobW PF02492.14 KFM09118.1 - 0.21 11.0 3.4 3 7.2 0.2 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 KFM09118.1 - 0.42 10.2 2.0 4.7 6.8 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF2075 PF09848.4 KFM09118.1 - 0.47 9.3 2.4 14 4.5 0.0 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF87 PF01935.12 KFM09118.1 - 0.65 9.7 11.0 0.31 10.8 0.2 2.8 3 0 0 3 3 2 0 Domain of unknown function DUF87 AAA_19 PF13245.1 KFM09118.1 - 1.2 8.9 7.3 3 7.6 0.3 3.2 3 0 0 3 3 2 0 Part of AAA domain ABC_membrane PF00664.18 KFM09119.1 - 2.2e-86 289.6 40.3 2.1e-46 158.5 10.7 2.7 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFM09119.1 - 4e-55 185.8 0.0 1.8e-29 102.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KFM09119.1 - 2.5e-10 39.9 0.0 2.4e-05 23.6 0.0 3.8 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KFM09119.1 - 1.4e-06 28.4 0.4 0.00018 21.5 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 KFM09119.1 - 2.7e-06 26.9 0.1 0.003 16.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 KFM09119.1 - 5.7e-06 26.8 0.4 0.0063 16.9 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_21 PF13304.1 KFM09119.1 - 6.4e-06 26.3 0.3 13 5.6 0.0 4.5 3 1 1 4 4 4 0 AAA domain MMR_HSR1 PF01926.18 KFM09119.1 - 9.7e-06 25.5 0.5 0.07 13.0 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 KFM09119.1 - 2e-05 23.8 0.8 0.0043 16.2 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC_ATPase PF09818.4 KFM09119.1 - 2.3e-05 23.1 0.0 0.0086 14.7 0.0 3.1 3 0 0 3 3 3 1 Predicted ATPase of the ABC class Zeta_toxin PF06414.7 KFM09119.1 - 0.00033 19.8 0.8 0.0097 15.0 0.1 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_23 PF13476.1 KFM09119.1 - 0.0057 17.0 0.2 2 8.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KFM09119.1 - 0.0099 15.3 3.5 0.92 9.0 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 KFM09119.1 - 0.015 16.1 2.8 2.5 8.9 0.0 3.3 2 1 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 KFM09119.1 - 0.015 14.8 0.0 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.18 KFM09119.1 - 0.023 14.4 5.5 0.024 14.4 0.2 2.8 3 0 0 3 3 2 0 Dynamin family DUF2370 PF10176.4 KFM09119.1 - 0.025 13.9 0.1 0.14 11.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) Arch_ATPase PF01637.13 KFM09119.1 - 0.039 13.6 1.6 0.17 11.5 0.0 2.5 3 0 0 3 3 2 0 Archaeal ATPase DUF87 PF01935.12 KFM09119.1 - 0.046 13.5 2.7 3.5 7.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_22 PF13401.1 KFM09119.1 - 0.049 13.7 2.5 5.8 7.0 0.0 3.5 2 1 0 2 2 2 0 AAA domain T2SE PF00437.15 KFM09119.1 - 0.065 12.1 0.0 0.91 8.3 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF815 PF05673.8 KFM09119.1 - 0.068 12.0 0.5 2.2 7.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) KAP_NTPase PF07693.9 KFM09119.1 - 0.084 11.8 0.0 0.084 11.8 0.0 2.1 3 0 0 3 3 2 0 KAP family P-loop domain AAA_18 PF13238.1 KFM09119.1 - 0.086 13.1 0.2 19 5.5 0.0 2.9 3 0 0 3 3 2 0 AAA domain MobB PF03205.9 KFM09119.1 - 0.1 12.2 1.5 2.2 8.0 0.2 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KFM09119.1 - 0.13 11.7 1.2 6.8 6.0 0.1 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_30 PF13604.1 KFM09119.1 - 0.29 10.6 0.7 31 4.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain FOP_dimer PF09398.5 KFM09120.1 - 4.2e-22 77.9 0.1 7.2e-22 77.1 0.0 1.4 1 0 0 1 1 1 1 FOP N terminal dimerisation domain LisH PF08513.6 KFM09120.1 - 0.46 10.3 4.6 0.12 12.1 0.8 1.8 2 0 0 2 2 2 0 LisH Myosin_head PF00063.16 KFM09121.1 - 9.3e-290 962.6 1.2 9.3e-290 962.6 0.9 5.0 3 1 1 5 5 5 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 KFM09121.1 - 2.4e-211 703.8 326.2 1.7e-210 701.0 169.2 2.9 1 1 1 2 2 2 2 Myosin tail Myosin_N PF02736.14 KFM09121.1 - 1.2e-16 60.1 1.8 2.1e-16 59.2 0.6 2.1 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain IQ PF00612.22 KFM09121.1 - 0.00032 20.0 0.2 0.0011 18.4 0.2 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif ADIP PF11559.3 KFM09121.1 - 0.0036 17.2 19.5 0.0036 17.2 13.5 14.8 1 1 12 14 14 14 2 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 KFM09121.1 - 0.0039 16.4 2.9 0.0039 16.4 2.0 9.3 3 2 6 10 10 10 6 Reovirus sigma C capsid protein NUDE_C PF04880.8 KFM09122.1 - 9.8e-40 136.6 1.5 9.8e-40 136.6 1.0 2.2 2 0 0 2 2 2 1 NUDE protein, C-terminal conserved region DMPK_coil PF08826.5 KFM09122.1 - 0.00086 19.1 8.5 0.00086 19.1 5.9 3.8 2 1 0 2 2 1 1 DMPK coiled coil domain like WEMBL PF05701.6 KFM09122.1 - 0.047 12.1 30.0 0.062 11.7 20.8 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light DUF904 PF06005.7 KFM09122.1 - 0.23 11.7 35.8 0.52 10.6 6.1 3.9 2 2 1 3 3 3 0 Protein of unknown function (DUF904) Pepsin-I3 PF06394.8 KFM09122.1 - 0.4 10.3 8.3 0.13 11.9 3.1 2.2 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain Flagellin_N PF00669.15 KFM09122.1 - 0.43 10.3 8.6 0.39 10.5 1.4 2.6 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region DUF2009 PF09418.5 KFM09122.1 - 0.44 9.2 6.0 0.4 9.4 3.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2009) TPR_MLP1_2 PF07926.7 KFM09122.1 - 0.67 9.7 35.9 0.39 10.4 7.8 3.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF972 PF06156.8 KFM09122.1 - 0.7 10.2 25.6 4.3 7.7 5.7 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF972) DUF148 PF02520.12 KFM09122.1 - 1.4 8.7 14.5 0.23 11.2 2.9 2.5 1 1 1 2 2 2 0 Domain of unknown function DUF148 GAS PF13851.1 KFM09122.1 - 1.6 7.8 33.6 0.81 8.8 13.1 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 KFM09122.1 - 1.6 7.8 4.8 5.9 5.9 0.7 2.4 1 1 2 3 3 3 0 Reovirus sigma C capsid protein DUF4231 PF14015.1 KFM09122.1 - 2.8 7.9 5.3 1.5 8.8 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) ADIP PF11559.3 KFM09122.1 - 3.5 7.5 32.8 0.26 11.1 6.0 3.1 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding OST-HTH PF12872.2 KFM09123.1 - 5.1e-54 180.0 2.2 3.7e-11 42.7 0.0 7.9 8 0 0 8 8 8 6 OST-HTH/LOTUS domain Limkain-b1 PF11608.3 KFM09123.1 - 4.3e-44 148.2 0.3 1.3e-43 146.6 0.2 1.8 1 0 0 1 1 1 1 Limkain b1 NYN PF01936.13 KFM09123.1 - 7.2e-19 68.5 0.0 1.8e-18 67.2 0.0 1.7 1 0 0 1 1 1 1 NYN domain RRM_5 PF13893.1 KFM09123.1 - 6.1e-11 42.0 0.0 1.2e-08 34.6 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFM09123.1 - 7.5e-08 31.9 0.0 0.00014 21.3 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM09123.1 - 3.2e-06 27.0 0.0 0.0011 18.9 0.0 2.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Stork_head PF10264.4 KFM09123.1 - 0.044 13.9 0.5 15 5.8 0.0 2.9 2 0 0 2 2 2 0 Winged helix Storkhead-box1 domain PAH PF02671.16 KFM09123.1 - 0.096 12.3 0.5 1.8 8.2 0.1 3.4 2 0 0 2 2 2 0 Paired amphipathic helix repeat FlbD PF06289.6 KFM09123.1 - 0.26 10.6 4.0 0.59 9.5 0.6 2.7 2 0 0 2 2 2 0 Flagellar protein (FlbD) DUF3585 PF12130.3 KFM09124.1 - 1.5e-32 112.3 17.9 1.9e-32 112.0 12.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3585) Tau95 PF09734.4 KFM09124.1 - 0.081 12.2 0.6 0.11 11.8 0.4 1.3 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit TRF PF08558.5 KFM09124.1 - 0.2 10.9 4.1 0.29 10.4 2.8 1.2 1 0 0 1 1 1 0 Telomere repeat binding factor (TRF) DUF1151 PF06625.6 KFM09124.1 - 0.96 9.2 13.2 0.51 10.0 7.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1151) Histone_HNS PF00816.16 KFM09124.1 - 3.4 8.2 8.8 0.41 11.1 2.3 2.2 2 1 0 2 2 2 0 H-NS histone family Pyridoxal_deC PF00282.14 KFM09125.1 - 1.1e-14 53.6 0.0 7.5e-12 44.3 0.0 2.2 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain N_Asn_amidohyd PF14736.1 KFM09126.1 - 1.1e-122 408.2 0.0 1.2e-122 408.0 0.0 1.0 1 0 0 1 1 1 1 Protein N-terminal asparagine amidohydrolase RRN3 PF05327.6 KFM09127.1 - 1.6e-165 551.4 1.7 1.8e-165 551.2 1.2 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 EF-hand_2 PF09068.6 KFM09127.1 - 0.09 12.8 0.0 0.26 11.3 0.0 1.9 1 1 0 1 1 1 0 EF hand Ribosomal_L1 PF00687.16 KFM09128.1 - 2.2e-52 177.6 0.8 2.5e-52 177.4 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family GTP_EFTU PF00009.22 KFM09129.1 - 7.4e-49 165.7 0.0 1.5e-48 164.7 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KFM09129.1 - 3.1e-22 78.5 0.2 3.1e-22 78.5 0.2 2.6 4 0 0 4 4 4 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KFM09129.1 - 3.2e-07 30.3 0.1 8.9e-07 28.9 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KFM09129.1 - 7e-05 22.7 0.1 0.00018 21.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 KFM09129.1 - 0.021 13.5 0.0 0.032 12.9 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Arf PF00025.16 KFM09129.1 - 0.052 12.7 0.0 1.2 8.3 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Miro PF08477.8 KFM09129.1 - 0.11 13.0 0.0 0.3 11.5 0.0 1.8 1 1 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 KFM09129.1 - 0.15 11.6 0.0 3.1 7.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain CDV3 PF15359.1 KFM09129.1 - 0.54 10.3 6.6 1.2 9.2 4.6 1.5 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 BCMA-Tall_bind PF09257.5 KFM09130.1 - 2.8e-16 59.1 9.6 6.3e-16 58.0 6.6 1.6 1 0 0 1 1 1 1 BCMA, TALL-1 binding DUF1049 PF06305.6 KFM09130.1 - 0.0016 17.8 0.4 0.0024 17.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1049) RUN PF02759.14 KFM09131.1 - 2e-24 85.8 0.1 3.6e-24 85.0 0.1 1.4 1 0 0 1 1 1 1 RUN domain PX PF00787.19 KFM09132.1 - 1.9e-18 66.2 4.1 2e-18 66.2 0.7 2.4 3 0 0 3 3 3 1 PX domain Rootletin PF15035.1 KFM09132.1 - 0.0094 15.9 5.6 0.0094 15.9 3.9 2.8 3 1 0 3 3 3 1 Ciliary rootlet component, centrosome cohesion NYD-SP28_assoc PF14775.1 KFM09132.1 - 0.02 14.5 6.0 1.2 8.8 0.7 3.1 2 0 0 2 2 2 0 Sperm tail C-terminal domain DUF2968 PF11180.3 KFM09132.1 - 0.31 10.4 8.8 0.35 10.2 3.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) TSC22 PF01166.13 KFM09132.1 - 1.5 8.8 9.2 2.5 8.1 1.4 2.8 1 1 1 2 2 2 0 TSC-22/dip/bun family Metallophos PF00149.23 KFM09133.1 - 2e-12 46.9 2.7 3.2e-12 46.2 1.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KFM09133.1 - 3e-10 40.1 0.0 4.5e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Shisa PF13908.1 KFM09134.1 - 5.5e-44 150.4 2.1 6.9e-44 150.1 1.5 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Chordopox_A13L PF05961.6 KFM09134.1 - 0.01 15.7 0.1 0.02 14.7 0.1 1.5 1 0 0 1 1 1 0 Chordopoxvirus A13L protein ERCC4 PF02732.10 KFM09136.1 - 4.9e-29 100.9 0.0 1.6e-28 99.2 0.0 2.0 1 0 0 1 1 1 1 ERCC4 domain HHH_5 PF14520.1 KFM09136.1 - 1.9e-06 27.9 0.0 4.4e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain T2SM_b PF10741.4 KFM09136.1 - 0.041 13.5 0.1 1.9 8.1 0.0 2.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b RPEL PF02755.10 KFM09137.1 - 7.8e-24 82.3 14.9 4.2e-09 35.4 0.0 4.3 4 0 0 4 4 4 3 RPEL repeat SAP PF02037.22 KFM09137.1 - 6e-12 44.7 4.2 6.5e-12 44.6 0.3 2.5 2 0 0 2 2 2 1 SAP domain CAF1 PF04857.15 KFM09138.1 - 1.6e-70 237.4 1.5 2.8e-70 236.6 1.0 1.4 1 0 0 1 1 1 1 CAF1 family ribonuclease RNA_bind PF08675.6 KFM09138.1 - 2.6e-46 155.5 0.4 4.8e-46 154.6 0.3 1.5 1 0 0 1 1 1 1 RNA binding domain R3H PF01424.17 KFM09138.1 - 2.9e-05 23.6 0.0 0.00012 21.6 0.0 2.1 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.17 KFM09138.1 - 0.027 14.0 0.0 0.072 12.7 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM09138.1 - 0.062 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAM_1 PF00536.25 KFM09139.1 - 8.5e-11 41.8 0.0 1.6e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-C3HC4_4 PF15227.1 KFM09139.1 - 5.5e-09 35.7 12.4 1.3e-08 34.6 8.6 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KFM09139.1 - 7e-08 32.0 13.6 1.4e-07 31.0 9.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SAM_2 PF07647.12 KFM09139.1 - 4.7e-07 29.5 0.1 8.6e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-C3HC4_2 PF13923.1 KFM09139.1 - 4e-06 26.7 14.3 8.4e-06 25.7 9.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM09139.1 - 1.1e-05 25.1 14.3 2.9e-05 23.7 9.9 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFM09139.1 - 6.1e-05 22.6 7.9 0.0001 21.8 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM09139.1 - 0.0058 16.3 11.8 0.011 15.3 8.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 KFM09139.1 - 0.0058 16.1 4.2 0.0058 16.1 2.9 2.5 2 1 1 3 3 3 1 RING/Ubox like zinc-binding domain PolC_DP2 PF03833.8 KFM09139.1 - 0.0091 13.7 0.6 0.012 13.3 0.4 1.1 1 0 0 1 1 1 1 DNA polymerase II large subunit DP2 SAM_PNT PF02198.11 KFM09139.1 - 0.013 15.1 0.1 0.053 13.2 0.1 1.9 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain zf-Apc11 PF12861.2 KFM09139.1 - 0.022 14.5 4.6 0.056 13.2 3.2 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KFM09139.1 - 0.037 13.7 9.5 0.04 13.6 5.2 2.1 2 0 0 2 2 2 0 RING-type zinc-finger zf-rbx1 PF12678.2 KFM09139.1 - 0.085 12.9 7.3 0.2 11.8 5.1 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger DUF1435 PF07256.7 KFM09139.1 - 0.43 10.5 5.5 0.14 12.1 0.5 2.5 2 1 1 3 3 2 0 Protein of unknown function (DUF1435) DUF1244 PF06844.6 KFM09139.1 - 9.8 6.0 6.9 6.2 6.7 2.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1244) Phospholip_A2_1 PF00068.14 KFM09140.1 - 6.6e-37 126.3 15.2 7.3e-37 126.1 10.5 1.0 1 0 0 1 1 1 1 Phospholipase A2 Parvo_coat_N PF08398.5 KFM09140.1 - 0.077 12.7 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus coat protein VP1 TPR_11 PF13414.1 KFM09141.1 - 2.3e-11 43.1 3.5 2.1e-09 36.8 0.1 2.4 1 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KFM09141.1 - 9.6e-08 31.3 2.8 0.0042 16.6 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat zf-CCCH PF00642.19 KFM09141.1 - 5.5e-05 22.7 1.9 5.5e-05 22.7 1.3 4.2 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C2H2_jaz PF12171.3 KFM09141.1 - 0.00053 20.0 5.3 0.00053 20.0 3.7 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding TPR_2 PF07719.12 KFM09141.1 - 0.0011 18.6 2.4 0.94 9.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFM09141.1 - 0.0039 17.2 1.0 0.011 15.8 0.7 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFM09141.1 - 0.0062 16.4 1.7 0.64 9.9 0.5 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 KFM09141.1 - 0.014 15.5 1.3 0.053 13.6 0.6 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-met PF12874.2 KFM09141.1 - 0.019 15.1 5.8 0.064 13.4 4.0 2.0 1 0 0 1 1 1 0 Zinc-finger of C2H2 type tRNA-synt_His PF13393.1 KFM09141.1 - 0.11 11.5 0.5 0.19 10.7 0.4 1.3 1 0 0 1 1 1 0 Histidyl-tRNA synthetase Thioredoxin PF00085.15 KFM09142.1 - 2.6e-23 81.6 0.0 8e-13 47.9 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_7 PF13899.1 KFM09142.1 - 4.2e-07 29.8 0.5 0.0026 17.7 0.0 2.9 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 KFM09142.1 - 1.6e-06 28.3 0.0 0.091 12.9 0.0 3.0 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KFM09142.1 - 1.7e-05 24.8 1.9 0.027 14.6 0.1 3.4 3 0 0 3 3 2 2 Thioredoxin-like APG6 PF04111.7 KFM09142.1 - 0.0019 17.2 17.2 0.0035 16.4 11.9 1.3 1 0 0 1 1 1 1 Autophagy protein Apg6 Macoilin PF09726.4 KFM09142.1 - 0.0075 14.6 13.8 0.011 14.0 9.6 1.2 1 0 0 1 1 1 1 Transmembrane protein ERM PF00769.14 KFM09142.1 - 0.02 14.4 24.4 0.029 13.8 16.9 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF836 PF05768.9 KFM09142.1 - 0.026 14.7 0.2 0.13 12.5 0.0 2.3 2 0 0 2 2 1 0 Glutaredoxin-like domain (DUF836) V_ATPase_I PF01496.14 KFM09142.1 - 0.033 12.0 10.1 0.054 11.3 7.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FUSC PF04632.7 KFM09142.1 - 0.1 10.9 7.0 0.15 10.4 4.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family OmpH PF03938.9 KFM09142.1 - 0.12 12.3 16.0 0.21 11.4 11.1 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Redoxin PF08534.5 KFM09142.1 - 0.15 11.6 0.0 2.2 7.8 0.0 2.4 2 0 0 2 2 2 0 Redoxin Mnd1 PF03962.10 KFM09142.1 - 0.25 10.9 14.7 0.32 10.6 9.4 1.8 2 0 0 2 2 2 0 Mnd1 family DUF3450 PF11932.3 KFM09142.1 - 0.91 8.7 17.3 3.1 6.9 11.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TMF_TATA_bd PF12325.3 KFM09142.1 - 1 9.0 21.2 0.27 10.9 12.1 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Spc24 PF08286.6 KFM09142.1 - 1.3 8.7 17.5 0.16 11.6 1.4 2.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF641 PF04859.7 KFM09142.1 - 1.5 8.5 14.3 1.3 8.8 3.4 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF972 PF06156.8 KFM09142.1 - 6.5 7.1 21.1 17 5.7 6.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DUF342 PF03961.8 KFM09142.1 - 9 4.5 10.8 15 3.8 7.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) SNN_transmemb PF09049.5 KFM09143.1 - 2e-24 84.9 9.7 2.6e-24 84.5 6.7 1.2 1 0 0 1 1 1 1 Stannin transmembrane SNN_linker PF09050.5 KFM09143.1 - 4.7e-21 73.9 3.3 6.4e-21 73.5 2.3 1.2 1 0 0 1 1 1 1 Stannin unstructured linker SNN_cytoplasm PF09051.5 KFM09143.1 - 1.2e-20 72.8 0.4 1.6e-20 72.4 0.3 1.2 1 0 0 1 1 1 1 Stannin cytoplasmic CD34_antigen PF06365.7 KFM09143.1 - 0.085 12.4 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family zf-LITAF-like PF10601.4 KFM09144.1 - 3.3e-29 100.5 10.1 4.4e-29 100.1 7.0 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-C4_Topoisom PF01396.14 KFM09144.1 - 0.044 13.2 2.5 1.1 8.8 0.3 2.4 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger UPF0547 PF10571.4 KFM09144.1 - 0.1 12.3 2.7 2 8.2 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Zn_Tnp_IS1 PF03811.8 KFM09144.1 - 0.12 11.8 3.2 6.3 6.3 0.9 2.5 2 0 0 2 2 2 0 InsA N-terminal domain SOCS_box PF07525.11 KFM09147.1 - 1e-10 41.3 0.1 2.2e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 SOCS box SH2 PF00017.19 KFM09147.1 - 1.3e-10 40.9 0.0 2.9e-10 39.7 0.0 1.6 2 0 0 2 2 2 1 SH2 domain Dexa_ind PF15198.1 KFM09148.1 - 2.3e-43 146.0 10.5 2.5e-43 145.9 7.3 1.0 1 0 0 1 1 1 1 Dexamethasone-induced NACHT PF05729.7 KFM09149.1 - 1.7e-35 122.1 0.0 4.3e-35 120.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain LRR_6 PF13516.1 KFM09149.1 - 2.4e-17 60.9 10.6 0.0002 21.0 0.0 5.4 5 0 0 5 5 4 4 Leucine Rich repeat LRR_4 PF12799.2 KFM09149.1 - 1.3e-14 53.3 10.0 7.4e-09 35.0 2.1 5.2 3 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM09149.1 - 4.6e-06 26.2 8.8 0.0021 17.7 0.9 4.4 3 1 1 4 4 4 2 Leucine rich repeat LRR_9 PF14580.1 KFM09149.1 - 8.4e-06 25.4 0.1 0.00024 20.7 0.1 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_7 PF13504.1 KFM09149.1 - 5.8e-05 22.6 3.5 6.1 7.5 0.0 5.8 5 0 0 5 5 4 1 Leucine rich repeat NB-ARC PF00931.17 KFM09149.1 - 0.00011 21.1 0.0 0.00048 19.0 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain LRR_1 PF00560.28 KFM09149.1 - 0.00014 21.4 6.0 0.88 9.8 0.0 5.4 5 0 0 5 5 5 2 Leucine Rich Repeat AAA PF00004.24 KFM09149.1 - 0.00075 19.7 0.0 0.0024 18.0 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFM09149.1 - 0.001 19.0 0.0 0.0036 17.3 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 KFM09149.1 - 0.02 14.0 0.6 0.1 11.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 KFM09149.1 - 0.022 14.9 0.0 0.049 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 KFM09149.1 - 0.12 12.1 0.3 0.75 9.5 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function DUF87 DUF846 PF05832.7 KFM09151.1 - 3.5e-52 175.8 14.9 3.9e-52 175.7 10.3 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) ParA PF10609.4 KFM09152.1 - 2e-38 130.1 0.4 9.5e-38 127.9 0.2 1.9 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 KFM09152.1 - 1.1e-06 28.1 0.0 1.4e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.13 KFM09152.1 - 0.024 13.8 0.0 0.038 13.1 0.0 1.3 1 1 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.1 KFM09152.1 - 0.061 12.9 0.0 0.083 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain TF_Zn_Ribbon PF08271.7 KFM09152.1 - 0.11 11.8 0.1 0.24 10.7 0.1 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding Tektin PF03148.9 KFM09153.1 - 2.2e-133 444.5 17.2 2.5e-133 444.3 11.9 1.0 1 0 0 1 1 1 1 Tektin family Vps23_core PF09454.5 KFM09153.1 - 0.0002 20.8 2.3 0.065 12.8 0.2 2.5 2 0 0 2 2 2 2 Vps23 core domain NpwBP PF12622.2 KFM09153.1 - 0.05 14.0 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 mRNA biogenesis factor TBCA PF02970.11 KFM09153.1 - 1 9.4 9.2 5.7 7.0 0.1 3.8 3 1 1 4 4 4 0 Tubulin binding cofactor A L31 PF09784.4 KFM09153.1 - 1.8 8.7 6.4 1.2 9.2 0.1 3.1 3 1 1 4 4 4 0 Mitochondrial ribosomal protein L31 PMP22_Claudin PF00822.15 KFM09154.1 - 2.4e-51 173.6 14.3 2.7e-51 173.5 9.9 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFM09154.1 - 4.1e-15 55.8 13.5 4.2e-15 55.8 8.8 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 KFM09154.1 - 0.00019 21.0 12.9 0.00038 20.1 8.9 1.6 1 1 0 1 1 1 1 Amastin surface glycoprotein SUR7 PF06687.7 KFM09154.1 - 0.00055 19.5 9.6 0.00055 19.5 6.7 3.2 1 1 1 2 2 2 1 SUR7/PalI family L_HGMIC_fpl PF10242.4 KFM09154.1 - 0.00084 19.3 12.6 0.0013 18.7 8.7 1.4 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_3 PF06653.6 KFM09154.1 - 0.011 15.4 16.3 0.03 14.0 11.3 1.7 1 1 0 1 1 1 0 Tight junction protein, Claudin-like Glucos_trans_II PF14264.1 KFM09154.1 - 0.018 14.0 9.1 0.1 11.5 4.3 2.1 2 0 0 2 2 2 0 Glucosyl transferase GtrII UPF0233 PF06781.7 KFM09154.1 - 0.17 11.5 1.6 1.1 8.9 0.3 2.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0233) TMEM37 PF15108.1 KFM09154.1 - 0.22 11.2 7.2 0.066 12.9 2.7 1.6 1 1 1 2 2 2 0 Voltage-dependent calcium channel gamma-like subunit protein family Fig1 PF12351.3 KFM09154.1 - 0.22 11.3 9.0 0.03 14.2 3.4 1.7 1 1 1 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Clc-like PF07062.7 KFM09154.1 - 0.35 10.0 16.0 0.44 9.7 6.1 2.1 1 1 1 2 2 2 0 Clc-like Cytochrom_B561 PF03188.11 KFM09154.1 - 0.41 10.4 6.1 0.16 11.7 2.3 1.8 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 DUF3290 PF11694.3 KFM09154.1 - 0.54 9.9 4.6 0.11 12.2 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) 7TMR-DISM_7TM PF07695.6 KFM09154.1 - 0.78 9.3 17.8 8.1 6.0 12.3 2.4 1 1 0 1 1 1 0 7TM diverse intracellular signalling DUF4064 PF13273.1 KFM09154.1 - 1.9 8.6 13.6 14 5.8 0.9 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF4064) DUF4117 PF13491.1 KFM09154.1 - 2.3 7.6 6.8 0.39 10.1 0.9 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4117) DUF202 PF02656.10 KFM09154.1 - 2.6 8.3 11.4 1.4 9.2 2.2 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF202) DUF4282 PF14110.1 KFM09154.1 - 2.9 8.1 10.4 0.13 12.4 0.7 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4282) E1-E2_ATPase PF00122.15 KFM09154.1 - 3.3 6.6 5.3 0.82 8.6 1.3 1.7 2 0 0 2 2 2 0 E1-E2 ATPase DUF3671 PF12420.3 KFM09154.1 - 6 6.8 8.4 7.6 6.5 1.3 2.5 1 1 1 2 2 2 0 Protein of unknown function NMDAR2_C PF10565.4 KFM09155.1 - 1.2e-210 701.7 32.8 1.4e-210 701.5 22.7 1.1 1 0 0 1 1 1 1 N-methyl D-aspartate receptor 2B3 C-terminus Lig_chan PF00060.21 KFM09155.1 - 1.6e-35 121.9 0.3 4.4e-35 120.5 0.1 1.9 2 0 0 2 2 2 1 Ligand-gated ion channel SBP_bac_3 PF00497.15 KFM09155.1 - 5.2e-24 84.7 0.0 2.5e-23 82.5 0.0 2.0 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.4 KFM09155.1 - 4.5e-20 71.3 0.5 1.2e-19 70.0 0.4 1.7 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site ANF_receptor PF01094.23 KFM09155.1 - 1.7e-05 23.7 0.1 2.8e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region TLV_coat PF00429.14 KFM09156.1 - 0.015 13.7 0.2 0.016 13.7 0.2 1.0 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) RVT_1 PF00078.22 KFM09157.1 - 3.4e-33 114.8 0.0 4.7e-33 114.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.9 KFM09157.1 - 3.7e-10 39.2 0.1 7.1e-10 38.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase thumb domain Ras PF00071.17 KFM09158.1 - 1.4e-12 47.2 0.6 2e-06 27.2 0.1 4.1 4 0 0 4 4 4 3 Ras family FF PF01846.14 KFM09158.1 - 3.3e-08 33.3 9.8 3.6e-06 26.8 0.8 3.8 3 0 0 3 3 3 2 FF domain GTP_EFTU PF00009.22 KFM09158.1 - 0.0037 16.7 0.1 0.0083 15.5 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Kelch_1 PF01344.20 KFM09159.1 - 5.3e-82 269.1 11.7 8.9e-16 57.1 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 KFM09159.1 - 1.4e-55 183.2 5.9 1.2e-10 41.0 0.0 6.3 2 2 4 6 6 6 6 Kelch motif Kelch_4 PF13418.1 KFM09159.1 - 1e-35 121.2 10.3 4.4e-08 32.7 0.0 6.3 5 1 1 6 6 6 6 Galactose oxidase, central domain BACK PF07707.10 KFM09159.1 - 2.4e-33 114.0 0.1 6e-33 112.7 0.1 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_3 PF13415.1 KFM09159.1 - 3.8e-33 112.8 10.2 9e-09 35.2 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.10 KFM09159.1 - 1.6e-31 106.8 7.9 8.6e-07 28.4 0.0 6.9 7 0 0 7 7 7 5 Kelch motif BTB PF00651.26 KFM09159.1 - 2e-29 101.8 0.4 4.9e-29 100.5 0.3 1.7 1 0 0 1 1 1 1 BTB/POZ domain Kelch_5 PF13854.1 KFM09159.1 - 4.8e-11 42.3 8.8 0.025 14.5 0.0 6.6 7 0 0 7 7 7 2 Kelch motif MOZART1 PF12554.3 KFM09162.1 - 3.4e-23 80.8 0.3 3.9e-23 80.6 0.2 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated BORA_N PF15280.1 KFM09163.1 - 4.1e-61 206.0 3.1 4.1e-61 206.0 2.2 2.0 2 0 0 2 2 2 1 Protein aurora borealis N-terminus Reo_sigmaC PF04582.7 KFM09164.1 - 0.072 12.2 20.5 0.021 13.9 2.4 4.3 3 1 0 4 4 4 0 Reovirus sigma C capsid protein zf-C2H2 PF00096.21 KFM09165.1 - 1.7e-15 56.2 20.5 7e-06 26.0 1.8 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM09165.1 - 2.8e-12 46.2 6.9 2.2e-07 30.7 0.7 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM09165.1 - 7.5e-11 41.5 19.8 0.00062 19.9 1.4 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 KFM09165.1 - 0.0015 18.6 6.2 0.039 14.1 0.5 3.0 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 KFM09165.1 - 0.057 13.6 15.5 0.17 12.1 0.0 4.3 4 0 0 4 4 4 0 C2H2-type zinc-finger domain IBR PF01485.16 KFM09165.1 - 0.2 11.5 4.3 1 9.2 3.0 2.0 1 1 0 1 1 1 0 IBR domain zf-C2H2_6 PF13912.1 KFM09165.1 - 0.92 9.5 4.3 0.45 10.4 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger WWbp PF10349.4 KFM09165.1 - 0.99 10.3 8.2 2.8 8.8 5.7 1.8 1 0 0 1 1 1 0 WW-domain ligand protein zf-BED PF02892.10 KFM09165.1 - 1.8 8.3 10.0 4.4 7.1 0.9 2.6 2 1 0 2 2 2 0 BED zinc finger zf-C2H2_jaz PF12171.3 KFM09165.1 - 8.5 6.6 11.3 3.5 7.8 0.1 3.4 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 KFM09166.1 - 2e-14 52.9 22.9 8.6e-06 25.7 2.1 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM09166.1 - 1.9e-11 43.6 8.9 8.7e-08 32.0 1.0 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM09166.1 - 1.6e-07 31.1 20.5 0.0083 16.3 0.9 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 KFM09166.1 - 0.017 15.3 3.6 2.3 8.5 0.3 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFM09166.1 - 0.11 12.6 4.0 4.2 7.6 0.4 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFM09166.1 - 2.1 8.3 7.5 0.43 10.5 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger HCaRG PF07258.9 KFM09167.1 - 1.2e-27 96.6 0.0 1.4e-27 96.3 0.0 1.0 1 0 0 1 1 1 1 HCaRG protein Peptidase_C12 PF01088.16 KFM09168.1 - 8e-72 240.8 0.0 8.9e-72 240.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 MmgE_PrpD PF03972.9 KFM09171.1 - 8.2e-65 218.6 0.0 1e-64 218.4 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DJ-1_PfpI PF01965.19 KFM09172.1 - 6.8e-12 45.0 0.8 1e-11 44.4 0.5 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family GATase_5 PF13507.1 KFM09172.1 - 0.069 12.0 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain CLN5 PF15014.1 KFM09173.1 - 1.7e-178 592.3 6.5 1.9e-178 592.2 4.5 1.0 1 0 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 5 Lipase3_N PF03893.11 KFM09173.1 - 0.055 13.3 0.2 0.16 11.7 0.1 1.9 1 0 0 1 1 1 0 Lipase 3 N-terminal region EIIA-man PF03610.11 KFM09173.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 PTS system fructose IIA component F-box-like PF12937.2 KFM09174.1 - 1.4e-08 34.2 3.0 2.6e-08 33.4 0.5 2.6 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KFM09174.1 - 2.2e-08 33.5 2.6 2.6e-08 33.2 0.1 2.5 3 0 0 3 3 3 1 F-box domain DUF4116 PF13475.1 KFM09174.1 - 0.0083 15.5 0.4 0.024 14.1 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4116) DnaJ PF00226.26 KFM09175.1 - 1.4e-09 37.5 0.0 1.7e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 KFM09175.1 - 0.0031 17.2 0.0 0.0034 17.1 0.0 1.0 1 0 0 1 1 1 1 Pam16 Sigma70_r4_2 PF08281.7 KFM09175.1 - 0.012 15.0 0.1 0.017 14.5 0.1 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 SLAIN PF15301.1 KFM09176.1 - 3.1e-145 484.0 25.0 3.6e-145 483.8 17.3 1.0 1 0 0 1 1 1 1 SLAIN motif-containing family 7tm_1 PF00001.16 KFM09177.1 - 5.1e-42 143.7 11.9 7.6e-42 143.2 8.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM09177.1 - 8e-10 38.2 11.8 2.1e-09 36.9 8.2 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM09177.1 - 6e-05 22.2 10.3 7.2e-05 22.0 5.1 2.2 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx PHO4 PF01384.15 KFM09177.1 - 0.4 9.2 3.5 0.77 8.3 2.5 1.4 1 1 0 1 1 1 0 Phosphate transporter family zf-RING_2 PF13639.1 KFM09178.1 - 2.2e-06 27.4 6.0 1e-05 25.2 4.1 2.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFM09178.1 - 0.00029 20.8 5.9 0.00029 20.8 4.1 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.9 KFM09178.1 - 0.00085 18.7 3.8 0.0025 17.2 2.6 1.7 1 0 0 1 1 1 1 P-11 zinc finger zf-C3HC4_3 PF13920.1 KFM09178.1 - 0.0011 18.5 4.5 0.0037 16.9 3.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFM09178.1 - 0.0018 18.3 5.6 0.0018 18.3 3.8 2.6 3 0 0 3 3 2 1 RING-H2 zinc finger Mnd1 PF03962.10 KFM09178.1 - 0.0082 15.8 7.0 0.0082 15.8 4.8 3.2 3 0 0 3 3 3 2 Mnd1 family BRCA-2_OB3 PF09104.5 KFM09178.1 - 0.0089 15.8 0.2 0.0089 15.8 0.2 2.0 2 0 0 2 2 2 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 zf-C3HC4 PF00097.20 KFM09178.1 - 0.01 15.4 6.4 0.01 15.4 4.4 3.1 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM09178.1 - 0.018 14.7 7.2 0.034 13.8 3.1 2.9 2 0 0 2 2 2 0 zinc-RING finger domain HrpB2 PF09487.5 KFM09178.1 - 0.04 14.0 2.3 0.086 13.0 0.2 2.6 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB2) DivIC PF04977.10 KFM09178.1 - 0.22 11.0 14.2 0.54 9.7 0.5 3.6 3 0 0 3 3 3 0 Septum formation initiator HALZ PF02183.13 KFM09178.1 - 0.28 10.9 16.0 0.095 12.4 1.2 3.3 3 0 0 3 3 2 0 Homeobox associated leucine zipper TSC22 PF01166.13 KFM09178.1 - 0.57 10.1 15.0 1.2 9.1 1.7 4.8 3 1 1 4 4 4 0 TSC-22/dip/bun family DUF904 PF06005.7 KFM09178.1 - 0.75 10.1 31.1 0.25 11.6 4.6 4.3 3 1 1 4 4 4 0 Protein of unknown function (DUF904) PEP-utilisers_N PF05524.8 KFM09178.1 - 1.1 9.0 5.0 0.29 10.9 0.2 2.4 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal DivIVA PF05103.8 KFM09178.1 - 2.6 8.1 24.3 0.075 13.0 2.8 3.5 4 1 0 4 4 3 0 DivIVA protein DUF2730 PF10805.3 KFM09178.1 - 3.6 7.3 6.6 13 5.5 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) zf-RING_4 PF14570.1 KFM09178.1 - 4.2 7.0 10.2 0.51 9.9 2.7 2.9 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain Syntaxin PF00804.20 KFM09178.1 - 5 7.3 19.2 0.13 12.3 2.1 3.9 4 0 0 4 4 3 0 Syntaxin RRM_5 PF13893.1 KFM09179.1 - 3.1e-19 68.5 0.0 1.7e-08 34.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM09179.1 - 5.1e-15 55.2 0.1 5.5e-08 32.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFM09179.1 - 3.8e-12 45.6 0.2 0.00011 21.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFM09179.1 - 7.8e-09 35.1 0.0 0.00025 20.7 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 KFM09179.1 - 0.0018 17.8 2.5 0.0038 16.8 1.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PWI PF01480.12 KFM09179.1 - 0.0058 16.6 0.2 0.0058 16.6 0.1 1.9 2 0 0 2 2 2 1 PWI domain RRM_3 PF08777.6 KFM09179.1 - 0.013 15.3 7.3 0.61 9.9 0.0 3.7 3 1 0 3 3 3 0 RNA binding motif RGS-like PF09128.6 KFM09179.1 - 0.072 12.5 0.1 0.072 12.5 0.1 2.8 2 1 0 2 2 2 0 Regulator of G protein signalling-like domain Nup35_RRM PF05172.8 KFM09179.1 - 0.11 12.2 0.1 24 4.7 0.0 3.0 2 1 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Clathrin_bdg PF15045.1 KFM09180.1 - 7.4e-25 86.2 0.1 1.8e-24 85.0 0.0 1.7 1 0 0 1 1 1 1 Clathrin-binding box of Aftiphilin, vesicle trafficking PDZ PF00595.19 KFM09181.1 - 4.1e-06 26.8 0.1 7.7e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) DIL PF01843.14 KFM09182.1 - 1.1e-29 102.4 0.7 3.3e-29 100.8 0.5 1.9 1 0 0 1 1 1 1 DIL domain PDZ PF00595.19 KFM09182.1 - 3.5e-17 62.3 0.5 8.4e-17 61.1 0.4 1.7 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) FHA PF00498.21 KFM09182.1 - 1.4e-07 31.5 0.0 3.4e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 FHA domain RA PF00788.18 KFM09182.1 - 3.6e-07 30.5 0.0 1.5e-06 28.5 0.0 2.1 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PDZ_2 PF13180.1 KFM09182.1 - 7.4e-05 22.5 0.4 0.0002 21.2 0.3 1.7 1 0 0 1 1 1 1 PDZ domain DUF4477 PF14780.1 KFM09182.1 - 0.0087 15.4 0.1 0.02 14.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) Kinesin PF00225.18 KFM09183.1 - 1.4e-82 277.0 0.1 1.6e-46 158.5 0.0 2.2 2 0 0 2 2 2 2 Kinesin motor domain Tup_N PF08581.5 KFM09183.1 - 0.026 14.7 5.0 0.083 13.0 3.5 1.8 1 0 0 1 1 1 0 Tup N-terminal FERM_M PF00373.13 KFM09184.1 - 9e-20 71.1 0.5 2.1e-19 69.9 0.4 1.6 1 0 0 1 1 1 1 FERM central domain FERM_C PF09380.5 KFM09184.1 - 2.9e-17 62.6 0.0 1.1e-16 60.8 0.0 1.9 2 0 0 2 2 2 1 FERM C-terminal PH-like domain FERM_N PF09379.5 KFM09184.1 - 6.7e-17 61.3 0.5 1.6e-16 60.1 0.4 1.7 1 0 0 1 1 1 1 FERM N-terminal domain Dapper PF15268.1 KFM09185.1 - 2.2e-221 737.6 40.3 2.5e-221 737.5 27.9 1.0 1 0 0 1 1 1 1 Dapper Sulfotransfer_1 PF00685.22 KFM09186.1 - 4.9e-44 150.5 0.2 5.6e-44 150.3 0.1 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulphotransf PF09037.5 KFM09186.1 - 0.0009 18.8 0.2 0.0022 17.5 0.0 1.7 1 1 0 1 1 1 1 Stf0 sulphotransferase Vasculin PF15337.1 KFM09186.1 - 0.011 16.1 1.8 0.63 10.5 0.1 2.2 2 0 0 2 2 2 0 Vascular protein family Vasculin-like 1 Sulfotransfer_1 PF00685.22 KFM09187.1 - 1.5e-30 106.4 0.2 1.6e-30 106.2 0.1 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Thyroglobulin_1 PF00086.13 KFM09188.1 - 4.4e-30 102.8 27.8 3.9e-16 58.1 3.1 3.1 3 0 0 3 3 3 2 Thyroglobulin type-1 repeat SPARC_Ca_bdg PF10591.4 KFM09188.1 - 7.2e-15 55.0 0.1 1.9e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Kazal_2 PF07648.10 KFM09188.1 - 2.3e-07 30.6 1.9 2.3e-07 30.6 1.3 2.2 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain EF-hand_7 PF13499.1 KFM09188.1 - 2.9e-05 24.0 0.0 0.00013 22.0 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KFM09188.1 - 3e-05 23.0 0.2 0.79 9.1 0.0 3.5 3 0 0 3 3 3 2 EF hand Kazal_1 PF00050.16 KFM09188.1 - 0.00025 20.9 3.9 0.00025 20.9 2.7 2.5 3 0 0 3 3 3 1 Kazal-type serine protease inhibitor domain EF-hand_6 PF13405.1 KFM09188.1 - 0.00032 20.3 0.2 0.98 9.4 0.0 3.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.1 KFM09188.1 - 0.0085 15.3 0.0 0.25 10.7 0.0 3.3 3 0 0 3 3 3 1 EF hand Laminin_EGF PF00053.19 KFM09188.1 - 9.4 6.2 16.8 2 8.4 1.8 3.7 3 0 0 3 3 3 0 Laminin EGF-like (Domains III and V) TSP_C PF05735.7 KFM09189.1 - 4.1e-72 241.9 3.1 6.4e-72 241.3 2.1 1.3 1 0 0 1 1 1 1 Thrombospondin C-terminal region TSP_3 PF02412.13 KFM09189.1 - 4.1e-57 189.3 139.2 6.1e-12 44.7 10.7 10.4 8 2 2 10 10 10 8 Thrombospondin type 3 repeat TSP_1 PF00090.14 KFM09189.1 - 1.5e-43 146.6 59.4 2.2e-16 59.7 6.4 4.7 4 0 0 4 4 4 3 Thrombospondin type 1 domain VWC PF00093.13 KFM09189.1 - 1.5e-13 50.6 17.5 1.5e-13 50.6 12.1 6.0 4 2 1 5 5 5 1 von Willebrand factor type C domain EGF_3 PF12947.2 KFM09189.1 - 2e-07 30.8 7.1 2e-07 30.8 4.9 6.1 6 0 0 6 6 6 2 EGF domain EGF_CA PF07645.10 KFM09189.1 - 4.1e-06 26.6 1.6 4.1e-06 26.6 1.1 5.5 4 0 0 4 4 4 3 Calcium-binding EGF domain EGF PF00008.22 KFM09189.1 - 0.00087 19.1 5.6 0.00087 19.1 3.9 4.6 3 0 0 3 3 3 1 EGF-like domain ROS_MUCR PF05443.6 KFM09190.1 - 0.025 14.3 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein PHD PF00628.24 KFM09192.1 - 6.8e-17 60.9 25.5 2.7e-09 36.5 7.4 2.4 1 1 1 2 2 2 2 PHD-finger PHD_2 PF13831.1 KFM09192.1 - 0.00022 20.4 4.7 0.00022 20.4 3.3 2.7 2 1 0 2 2 2 1 PHD-finger Requiem_N PF14051.1 KFM09192.1 - 0.02 14.8 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of DPF2/REQ. zf-PHD-like PF15446.1 KFM09192.1 - 0.096 11.9 17.9 0.041 13.1 2.0 3.0 3 1 1 4 4 4 0 PHD/FYVE-zinc-finger like domain Tctex-1 PF03645.8 KFM09193.1 - 2.1e-22 78.8 1.1 2.6e-22 78.5 0.8 1.1 1 0 0 1 1 1 1 Tctex-1 family DUF4209 PF13910.1 KFM09194.1 - 1.4e-25 89.1 0.4 5.4e-23 80.8 0.0 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4209) EGF PF00008.22 KFM09196.1 - 2.1e-45 152.2 150.3 9.5e-09 35.0 4.0 10.2 9 1 0 9 9 9 8 EGF-like domain DSL PF01414.14 KFM09196.1 - 5.1e-28 96.8 8.4 5.1e-28 96.8 5.9 7.8 6 2 2 8 8 8 2 Delta serrate ligand hEGF PF12661.2 KFM09196.1 - 4.7e-16 57.6 103.8 0.00065 19.6 1.6 11.5 11 0 0 11 11 11 8 Human growth factor-like EGF EGF_CA PF07645.10 KFM09196.1 - 6.6e-06 26.0 27.0 4.1e-05 23.4 6.6 10.3 5 2 5 10 10 10 5 Calcium-binding EGF domain EGF_2 PF07974.8 KFM09196.1 - 1e-05 25.6 172.7 0.016 15.3 7.8 10.4 10 0 0 10 10 10 6 EGF-like domain EGF_3 PF12947.2 KFM09196.1 - 6.4e-05 22.8 22.3 0.00062 19.6 7.1 9.8 7 2 1 8 8 8 4 EGF domain DUF899 PF05988.7 KFM09196.1 - 0.035 13.5 0.2 0.07 12.5 0.0 1.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF899) FAM176 PF14851.1 KFM09196.1 - 0.054 13.1 0.1 0.054 13.1 0.1 2.2 2 0 0 2 2 2 0 FAM176 family Neur_chan_memb PF02932.11 KFM09196.1 - 0.082 12.7 0.8 0.15 11.8 0.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Laminin_EGF PF00053.19 KFM09196.1 - 4.3 7.3 130.4 0.071 13.0 7.1 10.3 2 2 7 9 9 9 0 Laminin EGF-like (Domains III and V) Lamprin PF06403.6 KFM09197.1 - 0.00013 21.7 8.4 0.00048 19.8 5.8 1.7 1 1 0 1 1 1 1 Lamprin Chorion_1 PF01723.11 KFM09197.1 - 9.4 6.0 8.4 51 3.6 5.8 1.9 1 1 0 1 1 1 0 Chorion protein Proteasome PF00227.21 KFM09199.1 - 7.4e-37 126.4 0.1 9.2e-37 126.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Cytochrom_C1 PF02167.10 KFM09199.1 - 0.045 13.4 0.0 0.054 13.1 0.0 1.1 1 0 0 1 1 1 0 Cytochrome C1 family DUF2997 PF11211.3 KFM09199.1 - 0.086 12.2 0.7 0.55 9.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2997) TBP PF00352.16 KFM09200.1 - 1.5e-67 222.9 0.2 4.7e-33 112.3 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 KFM09200.1 - 0.00068 19.6 5.4 0.22 11.5 0.0 3.3 4 0 0 4 4 4 2 Domain of unknown function (DUF3378) Pollen_allerg_2 PF01620.11 KFM09200.1 - 0.039 14.2 0.6 0.1 12.9 0.1 1.8 1 1 0 2 2 2 0 Ribonuclease (pollen allergen) PDCD2_C PF04194.8 KFM09201.1 - 8.5e-51 171.8 0.3 9.8e-51 171.6 0.2 1.0 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain Acyltransferase PF01553.16 KFM09202.1 - 9.3e-24 83.3 0.0 1.7e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DUF4602 PF15375.1 KFM09203.1 - 4.4e-23 81.8 14.1 4.7e-23 81.7 9.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4602) Med19 PF10278.4 KFM09203.1 - 3.6 7.2 14.9 4.3 6.9 10.3 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 SPRY PF00622.23 KFM09204.1 - 1.3e-15 57.5 0.0 2.8e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 SPRY domain zf-B_box PF00643.19 KFM09204.1 - 1.2e-09 37.8 4.0 3.2e-09 36.5 2.8 1.8 1 0 0 1 1 1 1 B-box zinc finger fn3 PF00041.16 KFM09204.1 - 1.3e-08 34.8 0.0 2.8e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain PRY PF13765.1 KFM09204.1 - 1.8e-05 24.1 0.1 4.2e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 SPRY-associated domain Laminin_G_3 PF13385.1 KFM09204.1 - 0.00045 20.4 1.0 0.001 19.3 0.3 1.8 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Barstar PF01337.13 KFM09204.1 - 0.0097 15.7 0.7 0.2 11.5 0.0 2.2 1 1 1 2 2 2 1 Barstar (barnase inhibitor) YlbD_coat PF14071.1 KFM09204.1 - 0.045 13.8 1.7 7.4 6.6 0.0 2.6 2 0 0 2 2 2 0 Putative coat protein zf-UBR PF02207.15 KFM09204.1 - 0.094 12.4 5.1 0.75 9.5 3.5 2.4 1 1 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) IBR PF01485.16 KFM09204.1 - 0.73 9.7 6.8 0.8 9.6 2.0 2.5 2 0 0 2 2 2 0 IBR domain Arv1 PF04161.8 KFM09205.1 - 3e-34 118.7 3.8 3.7e-34 118.4 2.6 1.1 1 0 0 1 1 1 1 Arv1-like family MtrE PF04206.7 KFM09205.1 - 0.068 12.1 0.5 6 5.7 0.4 2.1 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit E Peptidase_C2 PF00648.16 KFM09207.1 - 6.6e-136 452.1 0.1 3e-135 449.9 0.0 1.9 2 0 0 2 2 2 1 Calpain family cysteine protease Calpain_III PF01067.17 KFM09207.1 - 2.9e-58 195.6 0.0 4.9e-58 194.9 0.0 1.4 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_1 PF00036.27 KFM09207.1 - 2.2e-10 39.0 1.8 0.00023 20.2 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 KFM09207.1 - 1.5e-09 36.9 2.6 0.0014 18.2 0.0 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 KFM09207.1 - 6.3e-08 32.6 2.1 0.0092 16.1 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KFM09207.1 - 2.6e-06 26.9 1.3 0.00035 20.1 0.1 3.4 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.1 KFM09207.1 - 0.0013 17.9 0.2 2.1 7.8 0.0 2.8 2 0 0 2 2 2 2 EF hand Ndufs5 PF10200.4 KFM09207.1 - 0.03 14.2 0.3 0.25 11.3 0.0 2.5 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Toprim PF01751.17 KFM09207.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 Toprim domain Serpin PF00079.15 KFM09208.1 - 1.1e-57 195.8 0.0 1.4e-57 195.5 0.0 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF3510 PF12022.3 KFM09209.1 - 1.6e-39 134.8 1.2 1.6e-38 131.5 0.3 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF3510) COG2 PF06148.6 KFM09209.1 - 2.7e-37 127.5 8.6 9.1e-37 125.8 2.3 3.5 4 0 0 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 KFM09209.1 - 0.00017 21.3 0.5 0.0028 17.4 0.0 2.8 2 0 0 2 2 2 1 Vps51/Vps67 DUF1664 PF07889.7 KFM09209.1 - 0.00076 19.2 2.4 0.0096 15.7 0.2 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) COG5 PF10392.4 KFM09209.1 - 0.19 11.6 7.4 0.49 10.3 0.2 3.2 3 1 0 3 3 3 0 Golgi transport complex subunit 5 Reo_sigmaC PF04582.7 KFM09209.1 - 0.24 10.5 4.1 0.16 11.0 0.1 2.3 3 0 0 3 3 3 0 Reovirus sigma C capsid protein DDE_Tnp_1_7 PF13843.1 KFM09210.1 - 4.5e-81 272.6 0.9 5.2e-81 272.4 0.6 1.0 1 0 0 1 1 1 1 Transposase IS4 HEPN PF05168.9 KFM09210.1 - 0.076 12.9 0.0 1.7 8.5 0.0 2.2 2 0 0 2 2 2 0 HEPN domain Glycos_transf_2 PF00535.21 KFM09211.1 - 5.7e-25 87.9 0.0 9.9e-25 87.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 KFM09211.1 - 1.1e-22 80.3 3.1 2e-22 79.5 2.2 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.1 KFM09211.1 - 2.3e-08 34.1 0.0 3.5e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 KFM09211.1 - 2.7e-06 26.7 0.0 5.3e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFM09211.1 - 4.1e-05 22.8 0.0 7.2e-05 22.0 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.1 KFM09211.1 - 7.5e-05 23.0 0.1 0.008 16.5 0.0 2.7 1 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.9 KFM09211.1 - 0.0035 16.7 0.7 0.43 9.9 0.1 2.4 1 1 1 2 2 2 2 Cytolethal distending toxin A/C family WD40 PF00400.27 KFM09212.1 - 9.4e-64 209.1 6.2 9.2e-13 47.5 0.1 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 KFM09212.1 - 9e-40 136.0 3.0 1.4e-39 135.4 2.1 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit Nup160 PF11715.3 KFM09212.1 - 4.6e-06 25.0 0.7 0.0012 17.1 0.1 2.8 1 1 0 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 KFM09212.1 - 0.00085 19.0 0.0 0.0091 15.7 0.0 2.5 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 KFM09212.1 - 0.063 12.3 0.0 0.41 9.7 0.0 2.2 2 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal CAGE1 PF15066.1 KFM09212.1 - 0.076 11.4 1.1 0.17 10.2 0.0 1.8 2 0 0 2 2 2 0 Cancer-associated gene protein 1 family ABC_membrane PF00664.18 KFM09213.1 - 2e-54 184.8 6.4 2.8e-54 184.3 4.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KFM09213.1 - 1.1e-33 116.4 0.0 2.4e-33 115.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 KFM09213.1 - 2.9e-07 29.9 0.1 6.2e-05 22.3 0.0 2.4 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KFM09213.1 - 4.7e-07 30.0 0.1 1.6e-05 25.0 0.1 2.3 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.4 KFM09213.1 - 4.6e-05 22.2 0.1 0.0018 16.9 0.0 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_25 PF13481.1 KFM09213.1 - 0.00036 19.9 0.5 0.0024 17.3 0.3 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFM09213.1 - 0.00051 20.0 0.9 0.0033 17.4 0.6 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 KFM09213.1 - 0.00062 19.9 0.2 0.011 15.9 0.1 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 KFM09213.1 - 0.001 18.5 0.1 0.0024 17.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KFM09213.1 - 0.0018 18.4 0.3 0.024 14.7 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFM09213.1 - 0.002 17.8 0.2 0.015 15.0 0.0 2.5 2 1 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 KFM09213.1 - 0.0061 17.3 0.1 0.014 16.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KFM09213.1 - 0.0074 15.4 0.0 0.017 14.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_5 PF07728.9 KFM09213.1 - 0.01 15.5 0.2 0.072 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KFM09213.1 - 0.015 15.1 0.0 0.17 11.7 0.0 2.4 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.1 KFM09213.1 - 0.05 13.1 0.1 0.3 10.6 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KFM09213.1 - 0.064 13.1 0.1 0.24 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 KFM09213.1 - 0.076 12.9 0.2 0.27 11.1 0.1 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 KFM09213.1 - 0.14 12.4 0.0 0.51 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain Nucleoporin_C PF03177.9 KFM09214.1 - 2.7e-89 300.2 18.0 3.7e-89 299.8 12.5 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 KFM09214.1 - 3.2e-27 95.3 0.2 5e-27 94.7 0.2 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Actin PF00022.14 KFM09215.1 - 7.6e-143 475.6 0.0 9.1e-143 475.3 0.0 1.0 1 0 0 1 1 1 1 Actin Ras PF00071.17 KFM09218.1 - 2.4e-59 199.3 0.2 2.8e-59 199.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM09218.1 - 1e-21 77.6 0.0 1.4e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM09218.1 - 2.9e-14 52.7 0.1 3.6e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFM09218.1 - 9.6e-07 28.4 0.0 1.8e-05 24.2 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFM09218.1 - 1.4e-05 25.0 0.0 2.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFM09218.1 - 7.5e-05 21.9 0.0 9.1e-05 21.6 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KFM09218.1 - 0.0015 17.7 0.0 0.0024 17.1 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 KFM09218.1 - 0.0036 16.8 0.0 0.015 14.8 0.0 1.9 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 KFM09218.1 - 0.0041 17.2 0.1 0.016 15.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFM09218.1 - 0.0086 16.0 0.1 0.017 15.1 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain ATP_bind_1 PF03029.12 KFM09218.1 - 0.014 14.9 0.0 2.1 7.8 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein KaiC PF06745.8 KFM09218.1 - 0.044 12.8 0.3 0.083 11.9 0.1 1.5 2 0 0 2 2 2 0 KaiC NACHT PF05729.7 KFM09218.1 - 0.062 12.9 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain BBS2_N PF14781.1 KFM09218.1 - 0.063 12.8 0.2 1.6 8.3 0.0 2.5 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal Septin PF00735.13 KFM09218.1 - 0.064 12.2 0.0 0.088 11.8 0.0 1.2 1 0 0 1 1 1 0 Septin Arch_ATPase PF01637.13 KFM09218.1 - 0.066 12.9 0.1 0.11 12.2 0.0 1.5 1 1 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 KFM09218.1 - 0.07 13.0 0.1 0.13 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 KFM09218.1 - 0.077 13.1 0.1 0.57 10.3 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 KFM09218.1 - 0.078 11.8 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.4 KFM09218.1 - 0.092 11.7 0.1 0.15 10.9 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Ras PF00071.17 KFM09220.1 - 2.8e-26 91.8 0.0 3.4e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM09220.1 - 3.7e-06 27.4 0.0 7.6e-06 26.4 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Lipase_GDSL_3 PF14606.1 KFM09220.1 - 0.0032 17.2 0.0 0.0042 16.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Vps51 PF08700.6 KFM09221.1 - 5.1e-08 32.6 0.2 1.8e-07 30.9 0.1 2.0 1 0 0 1 1 1 1 Vps51/Vps67 PH PF00169.24 KFM09221.1 - 0.00033 20.7 0.0 0.001 19.2 0.0 1.8 2 0 0 2 2 2 1 PH domain Adeno_terminal PF02459.10 KFM09221.1 - 0.013 13.7 3.0 0.025 12.7 2.0 1.4 1 0 0 1 1 1 0 Adenoviral DNA terminal protein PDDEXK_1 PF12705.2 KFM09221.1 - 0.019 14.3 0.2 0.039 13.3 0.1 1.5 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Dor1 PF04124.7 KFM09221.1 - 0.028 12.8 2.6 0.32 9.3 0.1 3.1 3 0 0 3 3 3 0 Dor1-like family DUF4591 PF15261.1 KFM09221.1 - 0.03 14.5 2.2 0.059 13.6 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4591) Sec3-PIP2_bind PF15277.1 KFM09221.1 - 0.079 12.8 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH SprT-like PF10263.4 KFM09222.1 - 5.6e-36 123.5 1.7 8.4e-36 122.9 1.2 1.3 1 0 0 1 1 1 1 SprT-like family WLM PF08325.5 KFM09222.1 - 0.0048 16.7 3.8 0.081 12.7 0.3 2.4 2 0 0 2 2 2 2 WLM domain 2OG-FeII_Oxy_3 PF13640.1 KFM09224.1 - 5.7e-18 65.2 0.0 8.8e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KFM09224.1 - 1.6e-09 37.9 0.0 2.9e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KFM09224.1 - 9.9e-06 25.1 0.0 2.5e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Translin PF01997.11 KFM09225.1 - 7e-60 202.0 0.1 8.4e-60 201.7 0.1 1.1 1 0 0 1 1 1 1 Translin family DUF3401 PF11881.3 KFM09226.1 - 1.9e-77 259.8 0.3 4.6e-77 258.6 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3401) Rap_GAP PF02145.10 KFM09226.1 - 1.2e-62 210.6 0.0 3.3e-62 209.2 0.0 1.8 1 0 0 1 1 1 1 Rap/ran-GAP PDZ PF00595.19 KFM09226.1 - 1.6e-05 24.9 0.0 3.2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) IncA PF04156.9 KFM09226.1 - 0.0069 15.9 3.3 0.018 14.6 2.3 1.6 1 0 0 1 1 1 1 IncA protein bZIP_2 PF07716.10 KFM09226.1 - 0.53 10.1 5.2 1.9 8.3 3.6 2.0 1 0 0 1 1 1 0 Basic region leucine zipper DUF2968 PF11180.3 KFM09226.1 - 6.3 6.1 12.3 0.35 10.2 4.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) HPHLAWLY PF14925.1 KFM09227.1 - 5.4e-65 219.6 29.7 1.9e-60 204.6 19.3 3.2 2 1 0 2 2 2 2 Domain of unknown function NTPase_1 PF03266.10 KFM09229.1 - 8.2e-56 188.3 0.2 9.1e-56 188.1 0.1 1.0 1 0 0 1 1 1 1 NTPase MobB PF03205.9 KFM09229.1 - 0.025 14.2 0.2 0.054 13.1 0.1 1.8 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 KFM09229.1 - 0.058 13.2 0.2 2.1 8.2 0.1 2.2 1 1 0 1 1 1 0 AAA domain Pkinase_Tyr PF07714.12 KFM09230.1 - 1e-30 106.7 0.0 1.9e-30 105.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM09230.1 - 2e-24 86.1 0.0 4.4e-24 85.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain DUF3552 PF12072.3 KFM09230.1 - 0.093 11.9 14.9 0.19 10.9 10.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) OmpH PF03938.9 KFM09230.1 - 8.2 6.3 11.0 16 5.3 7.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Ion_trans_2 PF07885.11 KFM09231.1 - 3.1e-34 116.5 19.5 1.2e-17 63.3 2.8 3.1 3 0 0 3 3 3 2 Ion channel Ferric_reduct PF01794.14 KFM09231.1 - 0.1 12.7 4.7 0.074 13.1 1.7 1.9 2 0 0 2 2 2 0 Ferric reductase like transmembrane component VIT1 PF01988.14 KFM09231.1 - 3.8 6.9 5.5 1.2 8.5 0.6 2.2 1 1 1 2 2 2 0 VIT family UPF0118 PF01594.11 KFM09231.1 - 4.3 6.2 15.0 5.4 5.9 8.8 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF20 EamA PF00892.15 KFM09232.1 - 2.6e-07 30.7 2.6 2.6e-07 30.7 1.8 4.0 3 1 1 4 4 4 1 EamA-like transporter family EmrE PF13536.1 KFM09232.1 - 5.7e-07 29.7 3.3 5.7e-07 29.7 2.3 3.9 2 1 1 4 4 4 1 Multidrug resistance efflux transporter TPT PF03151.11 KFM09232.1 - 1.1e-06 28.3 0.5 1.1e-06 28.3 0.3 2.7 2 1 0 2 2 2 1 Triose-phosphate Transporter family DUF914 PF06027.7 KFM09232.1 - 5.3e-06 25.5 22.6 8.2e-06 24.8 15.6 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) COX6B PF02297.12 KFM09233.1 - 2.7e-11 43.2 1.2 3.6e-11 42.8 0.8 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.8 KFM09233.1 - 0.0021 17.9 0.8 0.0035 17.2 0.5 1.4 1 0 0 1 1 1 1 CHCH domain zf-C3HC4 PF00097.20 KFM09234.1 - 0.00028 20.4 7.6 0.00054 19.5 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM09234.1 - 0.0026 17.7 7.5 0.0043 17.0 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM09234.1 - 0.052 13.2 7.9 0.079 12.6 5.5 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CK_II_beta PF01214.13 KFM09234.1 - 1.2 8.6 3.5 1.7 8.1 2.4 1.3 1 0 0 1 1 1 0 Casein kinase II regulatory subunit MAS20 PF02064.10 KFM09235.1 - 2e-32 111.6 0.1 2.3e-32 111.4 0.1 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor TPR_11 PF13414.1 KFM09235.1 - 0.0091 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 TPR repeat DUF221 PF02714.10 KFM09235.1 - 0.021 13.7 0.0 0.024 13.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF221 TPR_14 PF13428.1 KFM09235.1 - 0.036 14.6 0.2 0.11 13.1 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFM09235.1 - 0.044 13.3 0.1 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat SicP-binding PF09119.5 KFM09235.1 - 0.059 13.0 0.0 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 SicP binding TPR_2 PF07719.12 KFM09235.1 - 0.097 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat RRM_1 PF00076.17 KFM09236.1 - 6e-29 99.4 0.3 9.6e-16 57.1 0.0 3.4 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM09236.1 - 2.7e-21 75.3 0.3 1.9e-14 53.4 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM09236.1 - 6e-08 32.4 1.8 4.5e-05 23.2 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 KFM09236.1 - 0.016 14.9 0.0 2.3 7.9 0.0 2.5 2 1 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Cellulose_synt PF03552.9 KFM09236.1 - 4 5.6 9.0 6 5.0 6.2 1.3 1 0 0 1 1 1 0 Cellulose synthase RBB1NT PF08169.6 KFM09237.1 - 1.3e-38 130.8 2.2 1.3e-38 130.8 1.5 2.4 2 0 0 2 2 2 1 RBB1NT (NUC162) domain ARID PF01388.16 KFM09237.1 - 4.9e-25 87.2 0.0 1.5e-24 85.6 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Tudor-knot PF11717.3 KFM09237.1 - 5.2e-12 45.2 0.7 5.2e-12 45.2 0.5 2.6 3 0 0 3 3 3 1 RNA binding activity-knot of a chromodomain PWWP PF00855.12 KFM09237.1 - 0.025 14.7 0.2 0.025 14.7 0.2 4.9 4 1 1 5 5 5 0 PWWP domain polyprenyl_synt PF00348.12 KFM09238.1 - 4.8e-50 169.8 0.0 5.7e-50 169.5 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Galactosyl_T PF01762.16 KFM09239.1 - 3.6e-28 98.4 0.0 3.3e-25 88.8 0.0 2.2 2 0 0 2 2 2 2 Galactosyltransferase G-gamma PF00631.17 KFM09240.1 - 2.3e-17 62.5 0.0 2.6e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 GGL domain Beach PF02138.13 KFM09241.1 - 7.3e-101 337.1 0.7 1.3e-100 336.3 0.5 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 KFM09241.1 - 1.8e-24 85.5 0.0 5.3e-24 84.0 0.0 1.9 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 KFM09241.1 - 1.1e-13 50.5 16.7 5e-05 23.0 0.1 5.9 5 0 0 5 5 5 5 WD domain, G-beta repeat G2F PF07474.7 KFM09242.1 - 6.6e-79 263.7 0.5 1.1e-78 263.1 0.4 1.3 1 0 0 1 1 1 1 G2F domain Ldl_recept_b PF00058.12 KFM09242.1 - 6.8e-37 125.5 3.5 2.3e-10 40.6 0.0 4.9 5 0 0 5 5 5 3 Low-density lipoprotein receptor repeat class B EGF_3 PF12947.2 KFM09242.1 - 6.4e-32 109.2 102.1 2.5e-09 36.9 6.9 6.6 6 0 0 6 6 6 6 EGF domain NIDO PF06119.9 KFM09242.1 - 1.1e-22 80.5 0.5 3e-22 79.1 0.4 1.8 1 0 0 1 1 1 1 Nidogen-like EGF_CA PF07645.10 KFM09242.1 - 1.5e-20 72.8 93.7 1.2e-09 37.9 6.0 6.9 6 0 0 6 6 5 5 Calcium-binding EGF domain cEGF PF12662.2 KFM09242.1 - 2e-17 62.4 53.4 2.9e-06 26.7 1.2 6.7 6 0 0 6 6 6 5 Complement Clr-like EGF-like Thyroglobulin_1 PF00086.13 KFM09242.1 - 5.4e-17 60.8 2.0 3.2e-16 58.4 1.4 2.5 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat FXa_inhibition PF14670.1 KFM09242.1 - 8e-15 54.6 94.3 2e-08 34.2 4.9 6.5 6 0 0 6 6 6 4 Coagulation Factor Xa inhibitory site EGF PF00008.22 KFM09242.1 - 2.4e-10 40.1 89.2 0.0039 17.1 4.3 7.0 6 0 0 6 6 6 6 EGF-like domain SGL PF08450.7 KFM09242.1 - 4.3e-05 23.0 0.1 0.00014 21.3 0.0 2.0 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region EGF_MSP1_1 PF12946.2 KFM09242.1 - 0.1 12.3 66.1 0.017 14.8 1.2 5.9 6 0 0 6 6 5 0 MSP1 EGF domain 1 hEGF PF12661.2 KFM09242.1 - 3 8.1 25.2 0.97 9.6 0.2 6.9 6 0 0 6 6 6 0 Human growth factor-like EGF PspB PF06667.7 KFM09243.1 - 0.022 14.6 3.2 0.062 13.2 2.2 1.8 1 0 0 1 1 1 0 Phage shock protein B ERO1 PF04137.10 KFM09244.1 - 2.6e-133 444.4 0.0 3e-133 444.2 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Death PF00531.17 KFM09245.1 - 2e-11 43.5 0.1 3.5e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Death domain BP28CT PF08146.7 KFM09246.1 - 1.4e-44 151.5 6.3 1.4e-44 151.5 4.4 5.1 5 0 0 5 5 5 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 KFM09246.1 - 9.7e-25 86.8 0.8 9.7e-25 86.8 0.5 7.2 8 1 0 8 8 8 3 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.1 KFM09246.1 - 3.2e-10 40.1 1.8 0.23 11.7 0.0 6.8 5 1 1 6 6 6 4 HEAT repeats HEAT PF02985.17 KFM09246.1 - 1.3e-09 37.3 11.6 0.3 11.2 0.0 9.3 10 0 0 10 10 10 3 HEAT repeat HEAT_EZ PF13513.1 KFM09246.1 - 3.3e-05 24.2 9.6 0.12 12.8 0.0 6.7 5 0 0 5 5 5 2 HEAT-like repeat DUF2435 PF10363.4 KFM09246.1 - 4e-05 23.4 3.5 0.0011 18.7 0.1 4.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2435) Vac14_Fab1_bd PF12755.2 KFM09246.1 - 0.00074 19.8 1.1 0.1 12.9 0.0 4.2 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region Spectrin PF00435.16 KFM09247.1 - 8.2e-75 247.8 33.8 4.3e-25 88.0 5.9 4.4 4 0 0 4 4 4 4 Spectrin repeat CH PF00307.26 KFM09247.1 - 3e-42 143.0 0.2 6.7e-23 80.8 0.0 3.4 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 KFM09247.1 - 6.4e-27 93.3 0.0 3.7e-26 90.8 0.0 2.5 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 KFM09247.1 - 5.2e-13 48.4 0.1 3.9e-11 42.4 0.0 2.6 2 0 0 2 2 2 1 CAMSAP CH domain EF-hand_1 PF00036.27 KFM09247.1 - 8.5e-09 34.0 0.9 0.0025 16.9 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 KFM09247.1 - 2e-07 30.4 0.8 7.5e-07 28.6 0.2 2.4 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 KFM09247.1 - 1.6e-05 24.3 1.5 0.033 14.0 0.3 3.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 KFM09247.1 - 3.3e-05 23.9 0.6 0.00012 22.1 0.4 2.0 1 0 0 1 1 1 1 EF-hand domain pair XisI PF08869.6 KFM09247.1 - 0.24 11.5 5.4 0.096 12.8 0.5 2.6 2 0 0 2 2 2 0 XisI protein S-methyl_trans PF02574.11 KFM09248.1 - 7.9e-92 307.8 0.1 1.5e-91 306.8 0.0 1.5 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Met_synt_B12 PF02965.12 KFM09248.1 - 1.3e-81 272.8 0.0 2.1e-81 272.1 0.0 1.4 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain Pterin_bind PF00809.17 KFM09248.1 - 1.8e-44 151.6 0.8 2.3e-42 144.7 0.0 2.8 3 0 0 3 3 3 2 Pterin binding enzyme B12-binding_2 PF02607.12 KFM09248.1 - 2.8e-20 72.1 0.0 1.1e-19 70.2 0.0 2.1 2 0 0 2 2 2 1 B12 binding domain B12-binding PF02310.14 KFM09248.1 - 7.3e-17 61.3 0.1 2e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 B12 binding domain CdhD PF03599.11 KFM09248.1 - 0.0029 16.1 0.1 0.0054 15.2 0.1 1.4 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit IPT PF01745.11 KFM09248.1 - 0.062 12.4 0.1 0.15 11.1 0.0 1.7 1 0 0 1 1 1 0 Isopentenyl transferase Ins145_P3_rec PF08709.6 KFM09249.1 - 1.2e-16 60.3 0.2 1.3e-16 60.2 0.1 1.0 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor zf-RING_2 PF13639.1 KFM09250.1 - 1.8e-18 66.0 21.7 1.2e-10 41.0 3.7 3.1 2 1 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.1 KFM09250.1 - 1.1e-12 47.4 22.5 2.1e-07 30.5 4.3 3.0 2 1 1 3 3 3 2 zinc-RING finger domain zf-rbx1 PF12678.2 KFM09250.1 - 1.9e-12 47.0 17.1 2e-06 27.8 3.1 2.9 2 1 0 2 2 2 2 RING-H2 zinc finger zf-C3HC4 PF00097.20 KFM09250.1 - 5.7e-11 41.8 17.0 2.6e-06 26.9 4.2 3.0 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM09250.1 - 3.5e-10 39.7 20.1 3e-06 27.1 4.0 3.4 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM09250.1 - 6.5e-10 38.5 20.0 6.5e-06 25.7 3.2 3.2 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFM09250.1 - 9.7e-10 38.1 13.9 0.00024 20.8 2.6 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 11 RING-H2 finger IQ PF00612.22 KFM09250.1 - 1.3e-05 24.4 2.8 1.3e-05 24.4 2.0 2.2 2 0 0 2 2 2 1 IQ calmodulin-binding motif zf-RING_UBOX PF13445.1 KFM09250.1 - 0.00034 20.2 1.4 0.00034 20.2 1.0 3.9 2 2 1 3 3 3 1 RING-type zinc-finger zf-RING_4 PF14570.1 KFM09250.1 - 0.0047 16.4 13.4 0.2 11.2 0.3 3.5 3 1 0 3 3 3 2 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 KFM09250.1 - 0.0084 15.9 20.8 0.04 13.7 0.9 3.4 3 0 0 3 3 3 2 zinc finger of C3HC4-type, RING zf-UDP PF14569.1 KFM09250.1 - 0.0094 15.6 4.7 0.33 10.7 0.8 2.4 2 0 0 2 2 2 1 Zinc-binding RING-finger XFP PF03894.10 KFM09250.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase YdjO PF14169.1 KFM09250.1 - 0.2 11.1 2.3 2.2 7.7 0.0 3.1 3 0 0 3 3 3 0 Cold-inducible protein YdjO PHD PF00628.24 KFM09250.1 - 0.21 11.2 19.7 0.26 11.0 3.3 3.3 2 1 1 3 3 3 0 PHD-finger Rtf2 PF04641.7 KFM09250.1 - 0.52 9.4 14.0 0.11 11.7 1.4 2.8 3 1 0 3 3 3 0 Rtf2 RING-finger zf-Nse PF11789.3 KFM09250.1 - 2.4 7.7 14.7 0.55 9.7 2.5 3.0 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit LMBR1 PF04791.11 KFM09251.1 - 1.3e-142 475.7 23.4 3.6e-142 474.2 16.2 1.6 1 1 0 1 1 1 1 LMBR1-like membrane protein 60KD_IMP PF02096.15 KFM09251.1 - 0.0057 16.3 5.4 0.74 9.4 0.2 2.8 2 1 0 2 2 2 2 60Kd inner membrane protein DUF912 PF06024.7 KFM09251.1 - 0.016 15.2 0.3 0.016 15.2 0.2 3.6 4 0 0 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) MA3 PF02847.12 KFM09252.1 - 2.8e-24 84.9 1.7 2.8e-24 84.9 1.2 2.3 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.14 KFM09252.1 - 1.7e-23 83.1 6.3 1.7e-23 83.1 4.3 2.0 2 1 0 2 2 2 1 MIF4G domain HECT PF00632.20 KFM09253.1 - 3.4e-94 315.5 0.0 6.1e-94 314.7 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 KFM09253.1 - 0.00036 19.9 0.1 0.001 18.5 0.1 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif DnaJ PF00226.26 KFM09254.1 - 7.2e-29 99.3 4.7 1.2e-28 98.6 3.2 1.4 1 0 0 1 1 1 1 DnaJ domain Catalase-rel PF06628.7 KFM09254.1 - 0.042 13.7 0.1 0.086 12.7 0.1 1.5 1 0 0 1 1 1 0 Catalase-related immune-responsive PRESAN PF09687.5 KFM09255.1 - 0.0035 17.4 1.9 0.037 14.0 0.0 2.1 1 1 1 2 2 2 2 Plasmodium RESA N-terminal LON PF02190.11 KFM09255.1 - 0.021 14.5 0.0 0.022 14.4 0.0 1.1 1 0 0 1 1 1 0 ATP-dependent protease La (LON) domain DUF2973 PF11189.3 KFM09255.1 - 0.036 13.8 0.0 0.094 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2973) PmoA PF14100.1 KFM09255.1 - 0.072 12.2 0.0 0.45 9.6 0.0 1.9 2 0 0 2 2 2 0 Methane oxygenase PmoA tRNA-synt_2b PF00587.20 KFM09257.1 - 6.8e-32 110.4 0.0 1.8e-21 76.4 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 KFM09257.1 - 2.7e-05 24.1 2.7 0.00032 20.6 0.2 2.9 2 1 1 3 3 3 1 Seryl-tRNA synthetase N-terminal domain NOD PF06816.8 KFM09257.1 - 0.048 12.7 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 NOTCH protein Shisa PF13908.1 KFM09258.1 - 3.6e-12 46.8 11.6 3.8e-12 46.7 8.0 1.0 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Tropomodulin PF03250.9 KFM09259.1 - 2.7e-11 43.1 4.0 2.7e-11 43.1 2.8 2.7 2 1 0 2 2 2 1 Tropomodulin Tim17 PF02466.14 KFM09260.1 - 3.2e-34 117.7 4.4 3.8e-34 117.4 3.0 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family UQ_con PF00179.21 KFM09261.1 - 1.3e-41 141.2 0.0 1.5e-41 141.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFM09261.1 - 0.001 18.8 0.0 0.0012 18.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KFM09261.1 - 0.0017 18.2 0.0 0.0024 17.7 0.0 1.4 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KFM09261.1 - 0.0027 17.3 0.0 0.0054 16.3 0.0 1.5 1 1 0 1 1 1 1 UEV domain FAD_binding_7 PF03441.9 KFM09262.1 - 3.7e-101 337.9 0.3 4.7e-101 337.6 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 KFM09262.1 - 4.4e-38 130.6 0.0 2.5e-37 128.1 0.0 2.0 2 0 0 2 2 2 1 DNA photolyase Frag1 PF10277.4 KFM09263.1 - 6.1e-45 153.3 19.2 7.4e-45 153.0 13.3 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Bac_export_2 PF01312.14 KFM09263.1 - 0.6 8.9 6.9 0.5 9.1 3.5 1.6 1 1 1 2 2 2 0 FlhB HrpN YscU SpaS Family DUF3989 PF13150.1 KFM09263.1 - 5.4 6.5 9.1 5.9 6.4 1.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3989) CDP-OH_P_transf PF01066.16 KFM09264.1 - 5.8e-21 74.6 5.0 5.8e-21 74.6 3.5 3.0 2 1 1 3 3 3 1 CDP-alcohol phosphatidyltransferase DENN PF02141.16 KFM09265.1 - 4.9e-57 192.6 2.0 9.1e-57 191.7 1.4 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 KFM09265.1 - 1.2e-25 89.2 0.1 2.3e-25 88.3 0.1 1.5 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.14 KFM09265.1 - 1.5e-19 69.8 1.1 2.7e-19 68.9 0.8 1.5 1 0 0 1 1 1 1 dDENN domain HPD PF05044.7 KFM09265.1 - 0.042 13.5 0.1 0.07 12.8 0.1 1.3 1 0 0 1 1 1 0 Homeo-prospero domain 7tm_6 PF02949.15 KFM09265.1 - 0.049 12.4 0.0 0.1 11.4 0.0 1.4 1 1 0 1 1 1 0 7tm Odorant receptor Basic PF01586.11 KFM09266.1 - 2.2e-29 102.0 0.1 6.7e-29 100.4 0.0 1.8 2 0 0 2 2 2 1 Myogenic Basic domain HLH PF00010.21 KFM09266.1 - 4.5e-09 35.8 3.3 1e-08 34.7 2.3 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3080 PF11279.3 KFM09266.1 - 0.018 14.2 0.2 0.026 13.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) SAM_2 PF07647.12 KFM09267.1 - 2.1e-25 88.3 1.2 5e-11 42.2 0.1 3.9 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFM09267.1 - 5.7e-25 87.2 5.7 1.6e-12 47.4 0.1 4.2 4 0 0 4 4 4 3 SAM domain (Sterile alpha motif) F-box-like PF12937.2 KFM09268.1 - 0.11 12.2 2.3 0.24 11.1 1.6 1.5 1 0 0 1 1 1 0 F-box-like Glyco_transf_54 PF04666.8 KFM09269.1 - 6.1e-103 343.6 0.1 8e-103 343.2 0.0 1.1 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Tmemb_9 PF05434.6 KFM09270.1 - 1.3e-73 245.6 0.2 1.9e-73 245.1 0.1 1.2 1 0 0 1 1 1 1 TMEM9 Metal_resist PF13801.1 KFM09270.1 - 0.092 12.7 1.1 0.15 12.0 0.8 1.2 1 0 0 1 1 1 0 Heavy-metal resistance fn3 PF00041.16 KFM09271.1 - 2.8e-61 203.6 10.7 9e-16 57.7 0.1 5.1 6 0 0 6 6 6 4 Fibronectin type III domain I-set PF07679.11 KFM09271.1 - 5.3e-57 189.6 0.4 4.9e-20 71.1 0.0 6.7 7 0 0 7 7 7 4 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM09271.1 - 2e-20 72.6 0.0 4.7e-07 29.8 0.0 4.7 4 0 0 4 4 4 3 Immunoglobulin domain ig PF00047.20 KFM09271.1 - 8.1e-14 51.4 3.7 0.0031 17.6 0.0 6.0 6 0 0 6 6 6 3 Immunoglobulin domain Tissue_fac PF01108.12 KFM09271.1 - 1.2e-10 41.0 1.6 0.012 15.3 0.0 4.6 4 1 0 4 4 4 3 Tissue factor V-set PF07686.12 KFM09271.1 - 1.2e-09 38.0 3.9 0.15 11.9 0.0 5.8 4 3 1 5 5 5 4 Immunoglobulin V-set domain Receptor_2B4 PF11465.3 KFM09271.1 - 3e-09 36.7 3.2 0.0042 16.9 0.0 4.2 5 0 0 5 5 5 2 Natural killer cell receptor 2B4 Ig_3 PF13927.1 KFM09271.1 - 5.1e-08 33.3 9.3 0.00078 19.9 0.4 5.5 7 1 0 7 7 5 2 Immunoglobulin domain C2-set_2 PF08205.7 KFM09271.1 - 3.1e-06 26.9 0.1 0.045 13.6 0.0 3.7 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain SusE PF14292.1 KFM09271.1 - 2.2e-05 24.2 1.9 0.027 14.2 0.0 4.3 4 0 0 4 4 4 1 SusE outer membrane protein Y_Y_Y PF07495.8 KFM09271.1 - 0.0031 17.2 1.7 0.48 10.2 0.2 4.0 5 0 0 5 5 4 1 Y_Y_Y domain Herpes_gE PF02480.11 KFM09271.1 - 0.014 13.6 0.0 0.31 9.2 0.0 2.3 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E A2M_N PF01835.14 KFM09271.1 - 0.033 14.4 0.0 14 6.0 0.0 3.7 3 0 0 3 3 3 0 MG2 domain PhoD PF09423.5 KFM09271.1 - 0.037 12.6 0.0 0.5 8.8 0.0 2.5 3 0 0 3 3 3 0 PhoD-like phosphatase Reeler PF02014.11 KFM09271.1 - 0.075 13.2 2.5 24 5.2 0.0 4.3 4 0 0 4 4 4 0 Reeler domain Arm PF00514.18 KFM09272.1 - 8.1e-30 101.6 6.4 6.6e-10 38.4 0.0 7.6 9 0 0 9 9 9 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFM09272.1 - 3.7e-07 30.3 0.8 0.0018 18.5 0.0 3.1 2 2 0 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 KFM09272.1 - 0.00012 22.4 1.0 0.45 11.0 0.0 4.7 4 1 1 5 5 5 1 HEAT-like repeat HEAT PF02985.17 KFM09272.1 - 0.00037 20.3 0.1 0.7 10.1 0.0 3.8 3 0 0 3 3 3 1 HEAT repeat Adaptin_N PF01602.15 KFM09272.1 - 0.0027 16.0 0.1 0.76 8.0 0.0 2.4 2 1 0 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.8 KFM09272.1 - 0.065 12.3 1.3 0.83 8.7 0.1 2.8 2 1 1 3 3 3 0 Armadillo-like Mo25 PF08569.6 KFM09272.1 - 0.082 11.9 0.0 0.24 10.4 0.0 1.7 2 0 0 2 2 2 0 Mo25-like DUF383 PF04063.9 KFM09272.1 - 0.088 12.3 0.4 5 6.6 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF383) Troponin PF00992.15 KFM09273.1 - 7.3e-43 145.8 38.4 7.3e-40 136.0 20.7 2.0 1 1 1 2 2 2 2 Troponin DUF4250 PF14056.1 KFM09273.1 - 0.14 11.9 2.3 0.11 12.2 0.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) PLRV_ORF5 PF01690.12 KFM09273.1 - 8.5 5.3 14.3 10 5.1 9.9 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Caldesmon PF02029.10 KFM09274.1 - 2.5e-05 22.8 0.2 3e-05 22.6 0.2 1.0 1 0 0 1 1 1 1 Caldesmon Troponin PF00992.15 KFM09275.1 - 5e-50 168.9 5.2 7.1e-50 168.4 3.6 1.2 1 0 0 1 1 1 1 Troponin ADIP PF11559.3 KFM09275.1 - 0.041 13.7 1.2 0.086 12.7 0.8 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding XkdW PF09636.5 KFM09275.1 - 0.041 13.7 0.9 0.14 12.0 0.2 2.0 1 1 1 2 2 2 0 XkdW protein IFT20 PF14931.1 KFM09275.1 - 0.2 11.5 5.2 0.39 10.6 0.3 2.1 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 TMF_TATA_bd PF12325.3 KFM09275.1 - 1.4 8.7 8.6 0.64 9.7 2.1 2.5 2 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding PH PF00169.24 KFM09276.1 - 8.7e-06 25.8 0.0 1.2e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 PH domain LIM PF00412.17 KFM09277.1 - 3.9e-30 103.6 25.4 5.5e-17 61.5 3.7 2.1 2 0 0 2 2 2 2 LIM domain PHF5 PF03660.9 KFM09277.1 - 0.3 11.1 14.7 0.3 11.1 4.2 2.2 2 0 0 2 2 2 0 PHF5-like protein DZR PF12773.2 KFM09277.1 - 0.54 10.1 23.4 0.25 11.1 4.3 4.0 2 2 0 2 2 2 0 Double zinc ribbon DUF4428 PF14471.1 KFM09277.1 - 1.7 8.4 15.1 1 9.1 1.5 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) zf-NADH-PPase PF09297.6 KFM09277.1 - 3.9 7.0 9.0 5 6.7 0.2 3.9 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain zf-DNA_Pol PF08996.5 KFM09277.1 - 5.3 6.3 14.7 0.68 9.2 0.4 2.3 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger zf-C3HC4_2 PF13923.1 KFM09277.1 - 6.5 6.8 22.7 0.19 11.7 0.5 4.4 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-MYND PF01753.13 KFM09277.1 - 9 6.2 25.4 3.3 7.6 1.3 4.3 3 1 1 4 4 4 0 MYND finger Ank PF00023.25 KFM09278.1 - 1.4e-30 103.5 7.2 4.3e-09 35.7 0.1 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 KFM09278.1 - 2.5e-30 104.6 1.7 2.1e-14 53.6 0.2 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFM09278.1 - 6.6e-27 93.3 1.4 9.8e-13 48.2 0.0 4.1 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM09278.1 - 1.1e-23 82.6 4.1 2.4e-10 40.2 0.1 3.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM09278.1 - 1.3e-19 68.3 3.2 2.3e-05 24.1 0.1 4.8 4 0 0 4 4 4 4 Ankyrin repeat C2 PF00168.25 KFM09279.1 - 1.8e-54 181.5 0.5 1e-26 92.5 0.1 2.2 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.1 KFM09279.1 - 9.7e-05 21.9 0.0 0.13 11.8 0.0 2.4 2 0 0 2 2 2 2 CEP76 C2 domain DOCK-C2 PF14429.1 KFM09279.1 - 0.00015 21.5 0.4 0.14 11.7 0.0 2.4 2 0 0 2 2 2 2 C2 domain in Dock180 and Zizimin proteins EphA2_TM PF14575.1 KFM09279.1 - 0.037 14.4 0.0 0.099 13.0 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM52 PF14979.1 KFM09279.1 - 0.16 11.8 4.2 0.27 11.0 2.9 1.3 1 0 0 1 1 1 0 Transmembrane 52 Prominin PF05478.6 KFM09279.1 - 5.1 4.5 6.9 7.3 3.9 4.8 1.1 1 0 0 1 1 1 0 Prominin AAA_16 PF13191.1 KFM09280.1 - 0.00018 21.5 0.1 0.0021 18.0 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 KFM09280.1 - 0.00042 20.0 0.0 0.0013 18.4 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 KFM09280.1 - 0.00057 20.6 0.0 0.003 18.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KFM09280.1 - 0.0017 18.5 0.0 0.0052 16.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 KFM09280.1 - 0.0026 17.0 0.0 0.0052 16.0 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein IstB_IS21 PF01695.12 KFM09280.1 - 0.0031 16.9 0.0 0.0059 16.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 KFM09280.1 - 0.0031 17.6 0.0 0.0095 16.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KFM09280.1 - 0.008 16.1 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KFM09280.1 - 0.014 15.2 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KFM09280.1 - 0.015 15.4 0.0 0.04 14.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 KFM09280.1 - 0.018 14.7 0.0 0.042 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 KFM09280.1 - 0.026 13.6 0.5 0.075 12.2 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function, DUF258 T2SE PF00437.15 KFM09280.1 - 0.032 13.1 0.0 0.068 12.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Mg_chelatase PF01078.16 KFM09280.1 - 0.041 13.0 0.1 0.11 11.6 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 KFM09280.1 - 0.063 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Torsin PF06309.6 KFM09280.1 - 0.088 12.6 0.0 0.29 11.0 0.0 1.9 1 0 0 1 1 1 0 Torsin DUF4407 PF14362.1 KFM09280.1 - 0.32 9.9 1.9 0.7 8.8 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Bap31 PF05529.7 KFM09280.1 - 0.38 10.1 3.5 0.36 10.2 0.4 2.3 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like ATG16 PF08614.6 KFM09280.1 - 0.92 9.2 17.6 2.7 7.7 6.5 3.0 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Fib_alpha PF08702.5 KFM09280.1 - 1.6 8.8 7.7 0.99 9.5 0.7 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3138 PF11336.3 KFM09280.1 - 1.7 6.7 2.6 10 4.1 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) DUF4201 PF13870.1 KFM09280.1 - 4.7 6.6 18.9 1 8.7 4.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Peptidase_M1 PF01433.15 KFM09281.1 - 5.4e-49 167.3 0.0 7.3e-49 166.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 KFM09281.1 - 4.7e-41 139.7 0.8 7.2e-41 139.1 0.5 1.3 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 KFM09281.1 - 1.3e-18 67.2 0.0 3.2e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 Peptidase MA superfamily PLU-1 PF08429.6 KFM09282.1 - 6.7e-96 321.0 19.6 1.2e-91 307.1 4.9 3.5 3 0 0 3 3 3 3 PLU-1-like protein JmjC PF02373.17 KFM09282.1 - 2.1e-44 150.3 0.7 4.9e-44 149.2 0.5 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 KFM09282.1 - 2.9e-25 87.7 36.5 2.8e-11 42.9 2.8 4.1 4 0 0 4 4 4 3 PHD-finger ARID PF01388.16 KFM09282.1 - 1.3e-24 85.8 0.0 4.2e-24 84.2 0.0 2.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain zf-C5HC2 PF02928.11 KFM09282.1 - 6.1e-19 67.8 12.1 5.1e-18 64.8 8.4 2.8 1 0 0 1 1 1 1 C5HC2 zinc finger Tubulin PF00091.20 KFM09283.1 - 6.1e-69 232.1 0.0 7.9e-69 231.7 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFM09283.1 - 1.3e-50 170.6 0.0 1.9e-50 170.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KFM09283.1 - 0.0055 16.1 0.0 0.0097 15.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain LRR_8 PF13855.1 KFM09284.1 - 3.1e-79 260.6 50.4 7.6e-15 54.4 0.9 8.9 2 2 8 10 10 10 10 Leucine rich repeat LRR_4 PF12799.2 KFM09284.1 - 7.7e-46 153.0 27.9 2.3e-09 36.6 0.0 9.3 6 2 3 9 9 9 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM09284.1 - 2e-30 100.1 34.0 0.016 15.1 0.0 16.0 16 1 1 17 17 17 9 Leucine Rich Repeat LRR_5 PF13306.1 KFM09284.1 - 8.8e-29 99.8 0.0 5.2e-08 32.6 0.0 4.1 1 1 4 5 5 5 5 Leucine rich repeats (6 copies) LRR_6 PF13516.1 KFM09284.1 - 1.5e-16 58.5 26.2 0.86 9.8 0.0 14.4 14 2 2 16 16 16 5 Leucine Rich repeat LRR_7 PF13504.1 KFM09284.1 - 3e-16 56.6 30.3 0.14 12.4 0.0 13.9 14 0 0 14 14 14 5 Leucine rich repeat 7tm_1 PF00001.16 KFM09284.1 - 1.1e-11 44.3 16.2 1.7e-11 43.7 11.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_9 PF14580.1 KFM09284.1 - 1e-10 41.4 3.3 0.021 14.3 0.1 5.1 1 1 4 5 5 5 5 Leucine-rich repeat Y_phosphatase PF00102.22 KFM09285.1 - 4.5e-117 389.4 1.8 3.7e-82 275.1 0.2 2.7 3 0 0 3 3 3 2 Protein-tyrosine phosphatase fn3 PF00041.16 KFM09285.1 - 2.8e-22 78.6 3.3 1.2e-05 25.3 0.0 4.7 4 0 0 4 4 4 3 Fibronectin type III domain Y_phosphatase3 PF13350.1 KFM09285.1 - 9.4e-09 35.7 0.0 5.7e-05 23.4 0.0 2.5 2 0 0 2 2 2 2 Tyrosine phosphatase family DSPc PF00782.15 KFM09285.1 - 1.3e-06 28.0 0.0 0.00091 18.8 0.0 2.4 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 KFM09285.1 - 0.0018 18.3 0.0 0.051 13.6 0.0 2.4 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase2 PF03162.8 KFM09285.1 - 0.0037 16.6 0.2 2.9 7.2 0.0 2.8 2 0 0 2 2 2 2 Tyrosine phosphatase family CDKN3 PF05706.7 KFM09285.1 - 0.014 14.8 0.0 0.67 9.3 0.0 2.4 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) DUF1469 PF07332.6 KFM09285.1 - 0.16 11.7 0.7 0.29 10.8 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Y_phosphatase PF00102.22 KFM09286.1 - 1.3e-73 247.2 0.0 1.6e-73 246.9 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFM09286.1 - 7.3e-05 22.3 0.0 0.00016 21.2 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFM09286.1 - 0.0021 18.3 0.0 0.0043 17.3 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Ala_racemase_N PF01168.15 KFM09286.1 - 0.088 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Alanine racemase, N-terminal domain Arf PF00025.16 KFM09287.1 - 2.2e-39 134.4 0.0 2.6e-39 134.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KFM09287.1 - 5.1e-14 51.9 0.0 5.6e-14 51.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM09287.1 - 1.2e-06 29.0 0.0 4.4e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 KFM09287.1 - 4.7e-06 25.9 0.0 5.3e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KFM09287.1 - 1.6e-05 23.7 0.0 2.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit GTP_EFTU PF00009.22 KFM09287.1 - 0.0002 20.8 0.0 0.00023 20.6 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KFM09287.1 - 0.0023 17.1 0.0 0.0027 16.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit 7tm_1 PF00001.16 KFM09288.1 - 3.3e-24 85.4 16.8 4.6e-24 84.9 11.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PDR_CDR PF06422.7 KFM09288.1 - 0.004 16.7 3.7 0.077 12.6 0.1 2.7 2 0 0 2 2 2 2 CDR ABC transporter Ets PF00178.17 KFM09289.1 - 5.7e-29 100.0 2.1 9.6e-29 99.3 1.4 1.4 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.11 KFM09289.1 - 1.2e-17 63.4 0.0 4.8e-17 61.5 0.0 2.0 3 0 0 3 3 3 1 Sterile alpha motif (SAM)/Pointed domain EF1G PF00647.14 KFM09289.1 - 0.084 12.5 0.1 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 Elongation factor 1 gamma, conserved domain CH PF00307.26 KFM09289.1 - 0.14 12.2 0.2 0.74 9.8 0.1 2.2 2 0 0 2 2 2 0 Calponin homology (CH) domain AT_hook PF02178.14 KFM09289.1 - 0.14 11.9 5.2 0.33 10.7 3.6 1.7 1 0 0 1 1 1 0 AT hook motif Kinesin PF00225.18 KFM09290.1 - 1.5e-102 342.7 0.0 1.5e-102 342.7 0.0 2.5 2 0 0 2 2 2 1 Kinesin motor domain WD40 PF00400.27 KFM09290.1 - 5.2e-42 140.2 9.6 4.1e-06 26.4 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat Pkinase_Tyr PF07714.12 KFM09292.1 - 4.1e-93 311.1 0.0 6.4e-93 310.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ephrin_lbd PF01404.14 KFM09292.1 - 3.2e-79 264.8 0.3 6e-79 263.9 0.2 1.5 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase PF00069.20 KFM09292.1 - 8.6e-46 156.1 0.0 1.7e-45 155.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.16 KFM09292.1 - 8.6e-30 102.7 8.2 1.8e-15 56.8 0.9 3.8 4 0 0 4 4 4 2 Fibronectin type III domain SAM_1 PF00536.25 KFM09292.1 - 1.1e-23 83.1 0.0 2e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EphA2_TM PF14575.1 KFM09292.1 - 1.3e-23 83.1 0.0 2.8e-23 82.0 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SAM_2 PF07647.12 KFM09292.1 - 4.3e-21 74.5 0.0 8.3e-21 73.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) GCC2_GCC3 PF07699.8 KFM09292.1 - 3.5e-06 26.4 9.6 3.5e-06 26.4 6.6 2.6 2 0 0 2 2 2 1 GCC2 and GCC3 Tissue_fac PF01108.12 KFM09292.1 - 0.00052 19.7 0.3 0.16 11.7 0.0 2.7 2 0 0 2 2 2 1 Tissue factor CD34_antigen PF06365.7 KFM09292.1 - 0.0013 18.3 0.0 0.0046 16.6 0.0 1.8 2 0 0 2 2 2 1 CD34/Podocalyxin family SusE PF14292.1 KFM09292.1 - 0.0023 17.7 0.2 2.9 7.7 0.0 2.6 2 0 0 2 2 2 2 SusE outer membrane protein Interfer-bind PF09294.5 KFM09292.1 - 0.0053 16.7 0.7 0.046 13.7 0.1 2.6 3 0 0 3 3 3 1 Interferon-alpha/beta receptor, fibronectin type III DUF2318 PF10080.4 KFM09292.1 - 0.058 13.1 3.4 0.18 11.5 2.4 1.8 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) Pkinase_Tyr PF07714.12 KFM09293.1 - 4.4e-60 202.9 0.0 7.4e-60 202.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM09293.1 - 3.5e-56 190.2 0.0 8.2e-56 189.0 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.18 KFM09293.1 - 0.0016 18.2 0.2 0.0052 16.5 0.0 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Mnd1 PF03962.10 KFM09293.1 - 0.16 11.6 15.7 0.084 12.5 7.6 2.3 3 0 0 3 3 3 0 Mnd1 family BTB PF00651.26 KFM09294.1 - 4.2e-28 97.5 0.2 7e-28 96.8 0.2 1.4 1 0 0 1 1 1 1 BTB/POZ domain bZIP_Maf PF03131.12 KFM09294.1 - 3e-13 49.8 2.2 7.1e-13 48.6 1.5 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.16 KFM09294.1 - 1e-09 38.1 6.9 2.1e-09 37.2 4.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFM09294.1 - 1.7e-05 24.5 8.0 3.4e-05 23.5 5.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper Connexin PF00029.14 KFM09295.1 - 1.5e-49 166.4 0.8 1.8e-49 166.2 0.1 1.4 2 0 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 KFM09295.1 - 2.4e-24 84.9 0.6 5.5e-24 83.7 0.4 1.7 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain Prefoldin_2 PF01920.15 KFM09295.1 - 0.35 10.6 3.3 0.61 9.8 2.3 1.3 1 0 0 1 1 1 0 Prefoldin subunit AAA_5 PF07728.9 KFM09296.1 - 2.3e-124 409.6 0.0 6.4e-25 87.4 0.0 8.9 7 1 1 8 8 8 8 AAA domain (dynein-related subfamily) AAA PF00004.24 KFM09296.1 - 5.7e-26 91.2 0.5 0.00043 20.4 0.0 7.1 6 0 0 6 6 6 6 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFM09296.1 - 4.2e-24 85.5 6.7 6.3e-06 26.3 0.0 8.3 7 0 0 7 7 7 6 AAA ATPase domain AAA_3 PF07726.6 KFM09296.1 - 4.2e-23 81.3 0.0 2.6e-07 30.3 0.0 7.4 7 1 0 7 7 7 2 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KFM09296.1 - 3.9e-20 72.0 0.0 0.00036 20.4 0.0 7.6 6 1 1 7 7 7 4 AAA domain AAA_22 PF13401.1 KFM09296.1 - 2.4e-19 69.7 2.9 0.095 12.8 0.0 8.2 6 1 0 6 6 6 5 AAA domain Sigma54_activ_2 PF14532.1 KFM09296.1 - 4.7e-18 65.5 0.2 0.00033 20.7 0.0 7.9 6 0 0 6 6 6 4 Sigma-54 interaction domain AAA_17 PF13207.1 KFM09296.1 - 4.8e-18 66.1 0.1 0.071 13.9 0.0 7.8 6 0 0 6 6 6 4 AAA domain Miro PF08477.8 KFM09296.1 - 9.8e-15 55.1 0.0 1.7 9.1 0.0 7.4 6 0 0 6 6 6 2 Miro-like protein UPF0079 PF02367.12 KFM09296.1 - 1.1e-14 54.0 3.5 0.031 13.8 0.0 7.0 7 0 0 7 7 6 3 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activat PF00158.21 KFM09296.1 - 9e-14 51.2 1.0 0.62 9.5 0.0 7.0 7 0 0 7 7 7 3 Sigma-54 interaction domain ABC_tran PF00005.22 KFM09296.1 - 1.9e-13 50.8 10.2 0.016 15.4 0.0 8.3 8 0 0 8 8 6 3 ABC transporter AAA_19 PF13245.1 KFM09296.1 - 2.1e-12 46.6 7.4 0.088 12.5 0.0 6.3 6 0 0 6 6 6 4 Part of AAA domain AAA_33 PF13671.1 KFM09296.1 - 5.6e-12 45.7 2.1 0.051 13.4 0.0 7.9 7 1 0 7 7 6 2 AAA domain AAA_18 PF13238.1 KFM09296.1 - 6.2e-12 45.9 19.0 0.2 11.9 0.0 8.4 8 0 0 8 8 6 4 AAA domain Mg_chelatase PF01078.16 KFM09296.1 - 1.4e-11 43.9 0.5 1.1 8.3 0.0 8.1 9 1 0 9 9 7 2 Magnesium chelatase, subunit ChlI NACHT PF05729.7 KFM09296.1 - 1.7e-09 37.5 7.5 2.1 7.9 0.0 7.3 7 0 0 7 7 7 2 NACHT domain RNA_helicase PF00910.17 KFM09296.1 - 8.8e-09 35.5 0.5 4.6 7.4 0.0 6.9 6 0 0 6 6 6 1 RNA helicase AAA_25 PF13481.1 KFM09296.1 - 1.1e-08 34.7 0.8 1 8.7 0.0 5.7 6 0 0 6 6 5 2 AAA domain AAA_29 PF13555.1 KFM09296.1 - 1.9e-08 33.6 0.3 4.5 6.8 0.0 6.3 6 0 0 6 6 6 1 P-loop containing region of AAA domain AAA_28 PF13521.1 KFM09296.1 - 2.1e-08 34.2 5.4 1.4 8.8 0.0 7.1 6 0 0 6 6 6 1 AAA domain PduV-EutP PF10662.4 KFM09296.1 - 2.3e-08 33.6 3.6 0.26 10.7 0.0 6.4 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 KFM09296.1 - 1.8e-07 30.9 6.4 0.82 9.3 0.0 6.6 7 0 0 7 7 6 1 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 KFM09296.1 - 3.7e-07 29.3 2.5 4.2 6.1 0.1 6.2 6 0 0 6 6 6 1 Type II/IV secretion system protein SRP54 PF00448.17 KFM09296.1 - 9.4e-07 28.4 0.9 2.5 7.5 0.0 5.2 5 0 0 5 5 5 1 SRP54-type protein, GTPase domain RuvB_N PF05496.7 KFM09296.1 - 2.9e-06 26.5 1.5 6.2 5.7 0.0 5.8 6 0 0 6 6 6 0 Holliday junction DNA helicase ruvB N-terminus MMR_HSR1 PF01926.18 KFM09296.1 - 1.9e-05 24.6 0.0 14 5.6 0.0 6.5 6 0 0 6 6 6 0 50S ribosome-binding GTPase CPT PF07931.7 KFM09296.1 - 0.00017 21.2 1.0 11 5.5 0.0 6.0 7 0 0 7 7 6 0 Chloramphenicol phosphotransferase-like protein ATP-synt_ab PF00006.20 KFM09296.1 - 0.0032 16.9 0.0 4.8 6.6 0.0 4.0 4 0 0 4 4 3 0 ATP synthase alpha/beta family, nucleotide-binding domain KaiC PF06745.8 KFM09296.1 - 0.0092 15.1 0.4 2.4 7.1 0.0 3.8 3 0 0 3 3 3 1 KaiC AAA_7 PF12775.2 KFM09296.1 - 0.098 11.7 1.1 10 5.0 0.0 3.7 4 0 0 4 4 4 0 P-loop containing dynein motor region D3 NTPase_1 PF03266.10 KFM09296.1 - 3.7 7.2 7.7 50 3.5 0.0 4.9 6 0 0 6 6 5 0 NTPase Complex1_LYR PF05347.10 KFM09297.1 - 8.6e-19 67.0 0.3 1.1e-18 66.6 0.2 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KFM09297.1 - 2.4e-17 62.8 0.5 2.9e-17 62.6 0.3 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 KFM09297.1 - 7.3e-06 26.4 0.6 9e-06 26.1 0.4 1.2 1 0 0 1 1 1 1 Complex1_LYR-like ETC_C1_NDUFA5 PF04716.9 KFM09297.1 - 0.005 16.3 0.6 0.028 13.9 0.4 1.9 1 1 0 1 1 1 1 ETC complex I subunit conserved region Virulence_fact PF13769.1 KFM09297.1 - 0.1 12.4 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 Virulence factor Ank_2 PF12796.2 KFM09298.1 - 3.2e-65 216.4 27.0 1.2e-19 70.3 0.6 4.8 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 KFM09298.1 - 2.9e-49 162.5 33.4 1.1e-11 43.9 0.4 8.7 9 0 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.1 KFM09298.1 - 7.2e-42 141.0 20.1 2.8e-09 37.2 0.2 6.5 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM09298.1 - 1.7e-40 136.1 27.4 4.5e-11 42.6 0.3 6.8 2 1 6 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM09298.1 - 3.6e-36 119.5 20.0 1.1e-06 28.2 0.1 9.1 9 0 0 9 9 9 7 Ankyrin repeat XhlA PF10779.4 KFM09298.1 - 1.1 9.1 7.2 0.58 10.1 1.8 2.7 2 0 0 2 2 2 0 Haemolysin XhlA Gtr1_RagA PF04670.7 KFM09300.1 - 8.4e-74 247.5 0.7 1.2e-73 247.0 0.5 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 KFM09300.1 - 8.4e-07 28.3 0.0 1.1e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KFM09300.1 - 1.3e-05 24.5 0.1 2.8e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KFM09300.1 - 3e-05 24.4 0.0 0.00016 22.1 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Ras PF00071.17 KFM09300.1 - 0.0013 18.0 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 KFM09300.1 - 0.011 15.6 0.0 0.029 14.3 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.1 KFM09300.1 - 0.06 13.2 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain UQ_con PF00179.21 KFM09301.1 - 1.9e-21 75.9 0.0 3.2e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KFM09301.1 - 0.044 13.6 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 RWD domain Viral_Beta_CD PF04530.7 KFM09301.1 - 0.06 13.5 0.7 0.26 11.4 0.1 2.0 1 1 1 2 2 2 0 Viral Beta C/D like family Neur_chan_LBD PF02931.18 KFM09302.1 - 2.6e-55 186.9 0.5 4.4e-55 186.1 0.3 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFM09302.1 - 7.3e-43 147.1 4.4 9.5e-38 130.4 0.6 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 KFM09303.1 - 6e-55 185.7 0.7 9.2e-55 185.1 0.5 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFM09303.1 - 1.4e-41 142.9 8.7 9.7e-37 127.1 0.3 2.7 2 1 1 3 3 3 2 Neurotransmitter-gated ion-channel transmembrane region M20_dimer PF07687.9 KFM09304.1 - 2.8e-09 36.7 0.0 4.8e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 KFM09304.1 - 0.0013 18.3 0.0 0.0018 17.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 PNRC PF15365.1 KFM09305.1 - 1.9e-20 72.6 0.7 1.9e-20 72.6 0.5 2.0 2 1 0 2 2 2 1 Proline-rich nuclear receptor coactivator Amelogenin PF02948.10 KFM09305.1 - 0.33 11.5 4.5 0.46 11.1 3.1 1.3 1 1 0 1 1 1 0 Amelogenin mRNA_cap_enzyme PF01331.14 KFM09307.1 - 7.6e-72 241.0 0.3 1.3e-71 240.2 0.2 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 KFM09307.1 - 1e-30 106.1 0.0 1.9e-30 105.2 0.0 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DSPc PF00782.15 KFM09307.1 - 6.5e-11 41.9 0.0 1.4e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DNA_ligase_A_M PF01068.16 KFM09307.1 - 3.3e-07 29.8 0.0 6.7e-05 22.3 0.0 2.4 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Y_phosphatase PF00102.22 KFM09307.1 - 5.2e-05 22.6 0.0 9.4e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KFM09307.1 - 0.011 15.9 0.0 0.049 13.8 0.0 1.8 1 1 1 2 2 2 0 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 KFM09307.1 - 0.017 14.5 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF930 PF06059.7 KFM09309.1 - 0.013 15.7 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF930) SusE PF14292.1 KFM09309.1 - 0.019 14.8 0.1 0.026 14.3 0.1 1.2 1 0 0 1 1 1 0 SusE outer membrane protein UPF0542 PF15086.1 KFM09309.1 - 0.026 14.2 0.5 0.099 12.3 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 DUF1980 PF09323.5 KFM09309.1 - 0.12 12.0 0.7 1.6 8.4 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1980) DUF885 PF05960.6 KFM09310.1 - 0.015 14.4 0.1 0.015 14.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Nnf1 PF03980.9 KFM09310.1 - 0.039 13.9 0.8 5.8 6.9 0.2 2.2 2 0 0 2 2 2 0 Nnf1 HMG_box PF00505.14 KFM09310.1 - 0.18 12.1 2.1 0.2 11.9 0.0 2.0 2 1 0 2 2 2 0 HMG (high mobility group) box ORC3_N PF07034.6 KFM09311.1 - 1.2e-124 415.6 7.6 2.4e-124 414.6 5.3 1.5 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus TAFH PF07531.9 KFM09311.1 - 0.0053 16.3 5.0 1.7 8.2 0.0 4.0 3 0 0 3 3 3 2 NHR1 homology to TAF Vac14_Fab1_bd PF12755.2 KFM09311.1 - 0.049 14.0 0.1 0.58 10.5 0.0 2.7 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region tRNA-synt_1d PF00750.14 KFM09312.1 - 3.8e-74 249.6 0.8 4.7e-74 249.3 0.5 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 KFM09312.1 - 4.5e-22 78.2 0.5 4.5e-22 78.2 0.4 1.9 2 0 0 2 2 2 1 DALR anticodon binding domain tRNA-synt_1g PF09334.6 KFM09312.1 - 0.056 12.1 1.5 1.5 7.3 0.2 2.4 1 1 1 2 2 2 0 tRNA synthetases class I (M) Arg_tRNA_synt_N PF03485.11 KFM09312.1 - 0.12 12.8 0.1 0.91 10.1 0.0 2.6 3 0 0 3 3 3 0 Arginyl tRNA synthetase N terminal domain Nuc_sug_transp PF04142.10 KFM09313.1 - 3.1e-94 314.6 15.0 3.1e-94 314.6 10.4 1.4 2 0 0 2 2 2 1 Nucleotide-sugar transporter UAA PF08449.6 KFM09313.1 - 2.2e-09 36.6 16.5 2.2e-09 36.6 11.5 1.8 1 1 0 2 2 2 1 UAA transporter family TPT PF03151.11 KFM09313.1 - 9.7e-05 22.0 30.0 0.018 14.6 4.5 2.7 2 1 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 KFM09313.1 - 0.00025 21.1 2.9 0.00025 21.1 2.0 3.6 2 2 2 4 4 4 1 Multidrug resistance efflux transporter EamA PF00892.15 KFM09313.1 - 0.0066 16.4 3.6 0.0066 16.4 2.5 2.8 2 1 0 2 2 2 2 EamA-like transporter family DUF2839 PF10999.3 KFM09313.1 - 5.5 7.0 5.7 0.89 9.6 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2839) DUF3508 PF12018.3 KFM09314.1 - 2e-91 305.8 7.4 2e-91 305.8 5.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3508) YHS PF04945.8 KFM09314.1 - 0.018 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 YHS domain PulS_OutS PF09691.5 KFM09314.1 - 0.045 13.7 1.9 0.35 10.8 0.1 2.5 2 0 0 2 2 2 0 Bacterial chaperone lipoprotein (PulS_OutS) DUF4500 PF14937.1 KFM09315.1 - 2.8e-39 132.8 0.0 3.3e-39 132.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4500) Connexin PF00029.14 KFM09316.1 - 1.2e-46 157.1 0.4 2.1e-46 156.4 0.3 1.4 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 KFM09316.1 - 1.2e-28 98.6 7.0 3.1e-28 97.3 4.9 1.7 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain DUF3816 PF12822.2 KFM09316.1 - 2.1 8.1 6.3 51 3.7 4.4 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) zf-C2H2 PF00096.21 KFM09317.1 - 8.2e-10 38.4 106.1 0.0097 16.1 1.9 15.8 16 0 0 16 16 16 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM09317.1 - 4.2e-09 36.1 99.0 0.038 14.3 0.1 16.4 17 0 0 17 17 17 11 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM09317.1 - 1.5 8.8 52.0 1.1 9.2 0.2 10.6 11 0 0 11 11 11 0 C2H2-type zinc finger Hormone_6 PF00236.13 KFM09318.1 - 1.5e-54 181.8 8.9 1.8e-54 181.5 6.2 1.1 1 0 0 1 1 1 1 Glycoprotein hormone PDGF PF00341.12 KFM09318.1 - 0.064 13.3 9.6 0.12 12.4 6.6 1.5 1 1 0 1 1 1 0 PDGF/VEGF domain Fer4_3 PF12798.2 KFM09319.1 - 0.29 11.8 0.2 0.29 11.8 0.2 6.7 7 1 0 7 7 7 0 4Fe-4S binding domain eIF3_N PF09440.5 KFM09320.1 - 5e-45 152.9 4.0 5e-45 152.9 2.8 2.1 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 KFM09320.1 - 1.2e-18 67.3 0.1 5.4e-18 65.2 0.0 2.2 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 KFM09320.1 - 0.025 14.3 2.4 0.073 12.8 0.0 2.8 4 0 0 4 4 4 0 COP9 signalosome, subunit CSN8 HD_assoc PF13286.1 KFM09320.1 - 0.17 12.2 1.4 2.8 8.2 0.1 2.6 2 0 0 2 2 2 0 Phosphohydrolase-associated domain TPR_14 PF13428.1 KFM09321.1 - 3.8e-12 45.6 6.3 0.007 16.9 0.1 5.6 1 1 5 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFM09321.1 - 4.9e-12 46.1 3.3 0.0019 18.7 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFM09321.1 - 1.6e-10 40.0 11.1 0.00016 21.2 0.4 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 KFM09321.1 - 8.5e-10 38.1 12.3 5.4e-05 22.7 3.9 2.6 2 0 0 2 2 2 2 TPR repeat TPR_19 PF14559.1 KFM09321.1 - 1.5e-09 38.0 7.9 1.8e-05 24.9 0.2 3.6 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFM09321.1 - 3.4e-07 29.5 4.5 0.046 13.3 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFM09321.1 - 0.00024 20.6 11.8 0.021 14.5 0.0 4.5 5 1 1 6 6 5 2 Tetratricopeptide repeat NARP1 PF12569.3 KFM09321.1 - 0.00036 19.4 2.9 0.00036 19.4 2.0 2.4 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 TPR_12 PF13424.1 KFM09321.1 - 0.0016 18.3 17.5 0.091 12.7 3.0 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 KFM09321.1 - 0.0018 18.0 3.0 2.1 8.2 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFM09321.1 - 0.004 17.5 7.1 7.2 7.3 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 KFM09321.1 - 0.0054 16.8 5.9 0.016 15.3 2.8 3.5 1 1 3 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KFM09321.1 - 0.0062 16.2 1.7 3.6 7.6 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.1 KFM09321.1 - 0.0088 16.1 1.4 0.15 12.1 0.1 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 KFM09321.1 - 0.087 13.0 8.9 0.98 9.6 0.3 2.8 2 1 1 3 3 3 0 Alkyl sulfatase dimerisation Fis1_TPR_C PF14853.1 KFM09321.1 - 0.1 12.5 3.9 9.6 6.1 0.1 3.7 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.1 KFM09321.1 - 0.12 12.6 11.2 0.92 9.8 0.1 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat Neurensin PF14927.1 KFM09322.1 - 5.1e-09 35.6 0.0 7.3e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Neurensin 7tm_1 PF00001.16 KFM09323.1 - 5.3e-56 189.6 26.1 8.3e-56 188.9 18.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM09323.1 - 4.1e-10 39.2 24.6 8.5e-10 38.2 17.0 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM09323.1 - 0.0015 17.7 23.6 0.0015 17.7 16.3 2.5 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx CS PF04969.11 KFM09325.1 - 5.1e-19 68.5 1.5 9.8e-18 64.4 1.1 2.4 2 0 0 2 2 2 1 CS domain EnY2 PF10163.4 KFM09326.1 - 4.9e-35 119.3 0.4 5.5e-35 119.1 0.3 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 SAP PF02037.22 KFM09326.1 - 7.2 6.2 6.4 15 5.2 0.0 3.6 4 0 0 4 4 4 0 SAP domain LCM PF04072.9 KFM09327.1 - 4.5e-28 98.0 0.0 6.1e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_5 PF13854.1 KFM09327.1 - 2.9e-13 49.4 0.4 0.07 13.1 0.0 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.1 KFM09327.1 - 1.1e-11 44.3 2.9 0.27 11.0 0.0 6.3 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.1 KFM09327.1 - 5.4e-08 32.6 3.9 0.0085 16.2 0.0 5.0 3 1 2 5 5 5 2 Kelch motif Kelch_3 PF13415.1 KFM09327.1 - 1.1e-06 28.6 3.6 0.05 13.7 0.0 4.3 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.20 KFM09327.1 - 1.5e-05 24.4 0.1 0.033 13.7 0.0 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 KFM09327.1 - 1.6e-05 24.4 5.7 0.057 13.2 0.1 4.7 5 0 0 5 5 5 2 Kelch motif Glyoxal_oxid_N PF07250.6 KFM09327.1 - 0.035 13.1 0.0 0.46 9.5 0.0 2.3 2 0 0 2 2 2 0 Glyoxal oxidase N-terminus Pro-kuma_activ PF09286.6 KFM09328.1 - 1.5e-26 93.1 0.0 4.2e-26 91.7 0.0 1.6 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KFM09328.1 - 0.0033 16.6 0.0 0.0047 16.1 0.0 1.2 1 0 0 1 1 1 1 Subtilase family TFIID_30kDa PF03540.8 KFM09329.1 - 5.4e-28 96.5 0.0 7.5e-28 96.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.8 KFM09329.1 - 0.0026 17.4 0.0 0.076 12.7 0.0 2.1 1 1 1 2 2 2 1 Bromodomain associated Pkinase_Tyr PF07714.12 KFM09330.1 - 1.2e-33 116.3 0.0 1.7e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ank PF00023.25 KFM09330.1 - 3.7e-33 111.6 0.7 9.8e-10 37.7 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 KFM09330.1 - 4.1e-28 97.5 0.2 3.4e-23 81.7 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFM09330.1 - 8.9e-26 89.3 1.9 4.4e-11 42.6 0.1 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM09330.1 - 6.3e-21 72.3 0.1 1.7e-06 27.6 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 KFM09330.1 - 2.8e-20 72.2 0.7 7.6e-11 42.2 0.1 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Pkinase PF00069.20 KFM09330.1 - 1.4e-19 70.2 0.0 2.6e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Methyltransf_8 PF05148.10 KFM09331.1 - 2.9e-80 269.0 0.0 3.2e-80 268.8 0.0 1.0 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 KFM09331.1 - 5.1e-08 33.2 0.1 1.5e-07 31.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFM09331.1 - 1.4e-05 24.7 0.1 0.00045 19.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFM09331.1 - 2.3e-05 24.1 0.0 6.9e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFM09331.1 - 0.0011 18.3 0.2 0.48 9.7 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase small domain Ubie_methyltran PF01209.13 KFM09331.1 - 0.012 14.7 0.0 0.041 12.9 0.0 1.8 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KFM09331.1 - 0.026 14.9 0.2 1.9 9.0 0.0 2.7 2 1 1 3 3 3 0 Methyltransferase domain Methyltransf_26 PF13659.1 KFM09331.1 - 0.14 12.1 0.1 0.43 10.6 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase domain Retinal PF15449.1 KFM09332.1 - 0.42 8.2 5.7 0.49 7.9 3.9 1.0 1 0 0 1 1 1 0 Retinal protein WD40 PF00400.27 KFM09333.1 - 1e-21 75.9 11.7 7.3e-09 35.1 0.4 4.8 4 1 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 KFM09333.1 - 5.8e-09 34.6 2.7 0.018 13.1 0.1 3.1 1 1 2 3 3 3 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KFM09333.1 - 0.00028 20.4 0.6 0.0014 18.1 0.1 2.3 1 1 0 1 1 1 1 PQQ-like domain BBS2_Mid PF14783.1 KFM09333.1 - 0.016 15.0 0.0 1.7 8.4 0.0 2.7 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region CDtoxinA PF03498.9 KFM09333.1 - 0.026 13.8 0.1 0.04 13.2 0.1 1.3 1 0 0 1 1 1 0 Cytolethal distending toxin A/C family Nucleoporin_N PF08801.6 KFM09333.1 - 0.071 11.8 0.2 0.74 8.4 0.0 2.3 1 1 1 2 2 2 0 Nup133 N terminal like zf-Tim10_DDP PF02953.10 KFM09334.1 - 5.3e-14 51.2 0.3 6.7e-14 50.9 0.2 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Arfaptin PF06456.8 KFM09335.1 - 7.9e-80 267.4 8.5 8.9e-80 267.3 5.9 1.0 1 0 0 1 1 1 1 Arfaptin-like domain BAR PF03114.13 KFM09335.1 - 6.9e-06 25.7 10.1 9.7e-06 25.2 7.0 1.2 1 0 0 1 1 1 1 BAR domain Imm29 PF15575.1 KFM09335.1 - 0.016 14.8 2.3 0.021 14.4 0.4 1.8 2 0 0 2 2 2 0 Immunity protein 29 BAR_2 PF10455.4 KFM09335.1 - 0.1 11.4 5.0 0.097 11.5 2.7 1.3 1 1 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Fib_alpha PF08702.5 KFM09335.1 - 0.27 11.3 1.8 0.63 10.1 0.1 2.3 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.7 KFM09335.1 - 0.39 10.4 8.5 0.38 10.4 0.2 2.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Blo-t-5 PF11642.3 KFM09335.1 - 3.1 7.5 7.2 0.64 9.7 1.6 2.3 2 1 1 3 3 3 0 Mite allergen Blo t 5 Ribosomal_S17 PF00366.15 KFM09336.1 - 5.1e-31 106.5 2.0 7.8e-31 105.9 1.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 PRF PF06875.6 KFM09336.1 - 0.084 12.0 0.1 0.13 11.4 0.1 1.2 1 0 0 1 1 1 0 Plethodontid receptivity factor PRF 7tm_4 PF13853.1 KFM09337.1 - 2.2e-31 108.5 7.8 2.2e-31 108.5 5.4 2.1 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFM09337.1 - 3.4e-31 108.3 18.4 4.5e-31 107.9 12.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM09337.1 - 1.8e-10 40.4 9.1 1.8e-10 40.4 6.3 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx ubiquitin PF00240.18 KFM09338.1 - 3.4e-17 61.6 0.2 6.6e-17 60.6 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KFM09338.1 - 2.3e-07 30.3 0.3 5.7e-07 29.1 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.26 KFM09338.1 - 0.0007 19.3 0.2 0.0021 17.8 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD_2 PF13881.1 KFM09338.1 - 0.015 15.1 0.1 0.069 13.0 0.1 2.1 2 1 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like VQ PF05678.9 KFM09338.1 - 0.029 13.4 0.1 0.065 12.2 0.1 1.5 1 0 0 1 1 1 0 VQ motif XPC-binding PF09280.6 KFM09338.1 - 7.6 6.0 23.5 1 8.9 1.7 5.1 4 1 1 5 5 5 0 XPC-binding domain 7tm_4 PF13853.1 KFM09339.1 - 1.4e-16 60.5 7.4 1.4e-16 60.5 5.1 2.2 1 1 1 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFM09339.1 - 2.8e-14 52.8 15.8 3.6e-14 52.5 11.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Transposase_28 PF04195.7 KFM09339.1 - 0.13 11.5 1.0 0.23 10.7 0.7 1.4 1 0 0 1 1 1 0 Putative gypsy type transposon Folate_rec PF03024.9 KFM09340.1 - 2.3e-56 190.0 22.1 2.7e-56 189.7 15.3 1.1 1 0 0 1 1 1 1 Folate receptor family DUF4462 PF14692.1 KFM09341.1 - 0.12 11.6 0.4 0.17 11.1 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) 7tm_1 PF00001.16 KFM09342.1 - 2.7e-29 102.1 20.1 3.7e-29 101.6 14.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 KFM09342.1 - 1.2e-26 93.2 8.4 1.2e-26 93.2 5.8 2.1 2 1 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.4 KFM09342.1 - 2e-09 36.9 16.9 2.7e-09 36.5 11.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF1418 PF07214.7 KFM09342.1 - 0.19 11.3 0.1 0.19 11.3 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1418) Globin PF00042.17 KFM09343.1 - 3.1e-31 107.9 0.0 6e-31 107.0 0.0 1.4 2 0 0 2 2 2 1 Globin Globin PF00042.17 KFM09344.1 - 1.7e-28 99.1 0.0 3e-28 98.3 0.0 1.4 2 0 0 2 2 2 1 Globin Globin PF00042.17 KFM09345.1 - 1.5e-27 96.0 0.0 1.7e-27 95.9 0.0 1.0 1 0 0 1 1 1 1 Globin Globin PF00042.17 KFM09346.1 - 8.1e-29 100.1 0.0 1.4e-28 99.4 0.0 1.4 2 0 0 2 2 2 1 Globin Globin PF00042.17 KFM09347.1 - 5.9e-29 100.6 0.0 8.4e-29 100.1 0.0 1.2 1 0 0 1 1 1 1 Globin 7tm_1 PF00001.16 KFM09348.1 - 1.7e-26 92.9 24.0 2.3e-26 92.5 16.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 KFM09348.1 - 1.1e-25 90.1 10.5 1.1e-25 90.1 7.3 2.3 2 1 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.4 KFM09348.1 - 8e-06 25.1 17.8 7.7e-05 21.9 12.3 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF1129 PF06570.6 KFM09348.1 - 5.9 6.1 11.9 0.057 12.7 2.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) 7tm_1 PF00001.16 KFM09349.1 - 1.6e-25 89.7 21.5 1.9e-25 89.4 14.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 KFM09349.1 - 2.7e-25 88.8 12.3 2.7e-25 88.8 8.5 1.8 2 1 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.4 KFM09349.1 - 1.1e-06 28.0 23.1 2.3e-06 26.9 16.0 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx zf-C2H2_4 PF13894.1 KFM09352.1 - 0.014 15.7 5.0 1.5 9.3 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KFM09352.1 - 0.033 14.5 6.7 1.3 9.4 1.6 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM09352.1 - 2.6 8.4 15.5 1.7 9.1 1.2 2.7 3 0 0 3 3 3 0 Zinc-finger double domain NAD_binding_2 PF03446.10 KFM09353.1 - 3.7e-53 179.6 0.3 5.2e-53 179.2 0.2 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KFM09353.1 - 8.5e-39 132.3 0.1 1.3e-38 131.7 0.1 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.14 KFM09353.1 - 1.5e-10 40.5 0.0 2.4e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KFM09353.1 - 8.6e-09 35.7 0.0 2.4e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 KFM09353.1 - 0.00017 21.2 0.0 0.00039 20.1 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 KFM09353.1 - 0.0013 18.7 0.0 0.0049 16.8 0.0 2.1 1 1 0 1 1 1 1 TrkA-N domain IlvN PF07991.7 KFM09353.1 - 0.0033 16.8 0.1 0.0056 16.0 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain UDPG_MGDP_dh_N PF03721.9 KFM09353.1 - 0.0067 15.8 0.0 0.31 10.4 0.0 2.2 1 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PDH PF02153.12 KFM09353.1 - 0.012 14.5 0.1 0.015 14.1 0.0 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase NAD_Gly3P_dh_N PF01210.18 KFM09353.1 - 0.071 12.8 0.0 0.2 11.3 0.0 1.8 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF970 PF06153.6 KFM09353.1 - 0.075 13.0 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF970) Homeobox PF00046.24 KFM09354.1 - 0.0042 16.6 2.8 0.0077 15.8 2.0 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox PF00046.24 KFM09355.1 - 2.3e-19 68.7 7.9 2.7e-19 68.5 5.5 1.1 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFM09355.1 - 0.00041 20.0 2.0 0.00065 19.3 1.4 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 KFM09355.1 - 0.0094 14.9 0.1 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox PF00046.24 KFM09356.1 - 6.3e-21 73.7 6.1 1.2e-20 72.8 4.2 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFM09356.1 - 0.074 12.7 0.2 0.18 11.5 0.2 1.7 1 0 0 1 1 1 0 Homeobox KN domain RNA_pol_Rpc4 PF05132.9 KFM09356.1 - 0.46 10.4 2.3 0.88 9.5 1.6 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Hox9_act PF04617.8 KFM09357.1 - 4.3e-53 180.1 0.3 5.9e-53 179.7 0.2 1.2 1 0 0 1 1 1 1 Hox9 activation region Homeobox PF00046.24 KFM09357.1 - 1.4e-21 75.8 6.4 2.1e-21 75.2 4.5 1.3 1 0 0 1 1 1 1 Homeobox domain HTH_23 PF13384.1 KFM09357.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain Homeobox PF00046.24 KFM09358.1 - 3.9e-22 77.6 8.2 6.1e-22 77.0 5.7 1.3 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFM09358.1 - 0.021 14.5 1.1 0.041 13.5 0.8 1.5 1 0 0 1 1 1 0 Homeobox KN domain Hanta_G1 PF01567.11 KFM09358.1 - 0.11 10.6 0.0 0.16 10.1 0.0 1.1 1 0 0 1 1 1 0 Hantavirus glycoprotein G1 Homeobox PF00046.24 KFM09359.1 - 7.6e-22 76.6 8.8 7.6e-22 76.6 6.1 1.9 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 KFM09359.1 - 0.014 15.0 1.7 0.032 13.9 1.2 1.6 1 0 0 1 1 1 0 Homeobox KN domain Homeobox PF00046.24 KFM09360.1 - 2e-22 78.5 8.1 4e-22 77.5 5.6 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFM09360.1 - 0.02 14.6 2.1 0.055 13.1 0.7 2.2 2 0 0 2 2 2 0 Homeobox KN domain Terminase_5 PF06056.7 KFM09360.1 - 0.079 12.5 0.3 0.21 11.1 0.2 1.7 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) DUF605 PF04652.11 KFM09360.1 - 1.3 8.3 11.7 1.5 8.0 8.1 1.1 1 0 0 1 1 1 0 Vta1 like DUF566 PF04484.7 KFM09360.1 - 7.7 5.9 8.5 9.9 5.5 5.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF4074 PF13293.1 KFM09361.1 - 7.1e-38 128.6 8.3 7.1e-38 128.6 5.7 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4074) Homeobox PF00046.24 KFM09361.1 - 1e-21 76.2 5.0 2.1e-21 75.3 3.5 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox PF00046.24 KFM09362.1 - 5.7e-23 80.3 7.4 7.3e-23 79.9 5.1 1.1 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFM09362.1 - 0.19 11.4 1.8 0.27 10.9 0.2 2.0 2 0 0 2 2 2 0 Homeobox KN domain PH PF00169.24 KFM09363.1 - 3.1e-13 49.8 1.4 3.3e-13 49.7 0.4 1.5 2 0 0 2 2 2 1 PH domain SH3_1 PF00018.23 KFM09363.1 - 1.4e-11 43.5 0.3 4.2e-11 42.0 0.2 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFM09363.1 - 2.5e-11 42.9 0.2 6.1e-11 41.7 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFM09363.1 - 6e-11 41.6 0.2 1.5e-10 40.3 0.1 1.7 1 1 0 1 1 1 1 Variant SH3 domain PH_9 PF15410.1 KFM09363.1 - 1.3e-05 25.3 0.4 3.3e-05 24.0 0.3 1.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 KFM09363.1 - 1.7e-05 24.6 0.1 3.4e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KFM09363.1 - 0.00018 21.7 3.4 0.001 19.3 2.4 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PX PF00787.19 KFM09364.1 - 4.6e-24 84.3 3.0 6.3e-24 83.9 2.1 1.2 1 0 0 1 1 1 1 PX domain Chromo_shadow PF01393.14 KFM09365.1 - 9.1e-41 137.5 0.0 5.6e-35 118.9 0.0 2.2 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.19 KFM09365.1 - 1.3e-22 79.2 0.2 3.9e-17 61.6 0.1 2.7 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.1 KFM09365.1 - 0.012 15.5 0.2 0.031 14.1 0.1 1.7 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 RRM_1 PF00076.17 KFM09366.1 - 2.6e-37 126.2 0.0 3.2e-18 65.1 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM09366.1 - 1.6e-33 114.5 0.0 8e-17 60.9 0.0 2.4 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM09366.1 - 9.8e-12 44.5 0.0 4e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 KFM09366.1 - 0.012 15.0 0.5 0.52 9.8 0.1 2.6 2 0 0 2 2 2 0 Ribonuclease B OB domain NID PF07292.8 KFM09366.1 - 0.54 10.3 0.1 0.54 10.3 0.0 2.8 3 0 0 3 3 3 0 Nmi/IFP 35 domain (NID) bZIP_Maf PF03131.12 KFM09367.1 - 6e-22 77.7 5.0 1.4e-21 76.5 3.5 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.16 KFM09367.1 - 3.4e-08 33.3 12.8 5.8e-08 32.5 8.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFM09367.1 - 4.5e-06 26.3 7.7 4.5e-06 26.3 5.3 1.8 2 0 0 2 2 2 1 Basic region leucine zipper DUF724 PF05266.9 KFM09367.1 - 0.0049 16.5 1.9 0.0089 15.6 1.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF724) Seryl_tRNA_N PF02403.17 KFM09367.1 - 0.054 13.5 4.0 0.13 12.2 2.8 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain FlaC_arch PF05377.6 KFM09367.1 - 0.15 11.9 0.5 0.32 10.9 0.3 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) FARP PF01581.11 KFM09368.1 - 0.043 14.0 0.9 69 4.4 0.0 3.7 3 0 0 3 3 3 0 FMRFamide related peptide family AAA-ATPase_like PF09820.4 KFM09368.1 - 0.044 12.9 0.0 0.083 12.0 0.0 1.4 1 0 0 1 1 1 0 Predicted AAA-ATPase NPFF PF15085.1 KFM09368.1 - 0.099 12.9 3.1 2.9 8.2 0.3 2.8 1 1 1 2 2 2 0 Neuropeptide FF Cytochrom_C PF00034.16 KFM09369.1 - 9.3e-12 45.6 0.0 1.3e-11 45.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 KFM09369.1 - 3.7e-07 30.1 1.6 1.5e-06 28.2 1.1 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 KFM09369.1 - 2.2e-05 23.9 2.6 0.00031 20.1 1.8 2.2 1 1 0 1 1 1 1 Cytochrome c-550 domain UPF0128 PF03673.8 KFM09369.1 - 0.0085 15.3 0.1 0.0085 15.3 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0128) Cytochrom_C1 PF02167.10 KFM09369.1 - 0.14 11.7 0.3 0.16 11.5 0.2 1.4 1 1 0 1 1 1 0 Cytochrome C1 family Oxysterol_BP PF01237.13 KFM09370.1 - 2.3e-133 444.0 2.1 3.5e-133 443.4 0.7 1.8 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 KFM09370.1 - 7e-12 45.2 0.1 1.7e-11 43.9 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KFM09370.1 - 1.6e-07 31.4 2.0 2.9e-06 27.4 0.5 2.8 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 KFM09370.1 - 0.01 16.0 2.2 0.9 9.8 1.5 2.9 1 1 0 1 1 1 0 Pleckstrin homology domain Gasdermin PF04598.7 KFM09371.1 - 1e-131 439.8 5.1 1.2e-131 439.6 3.5 1.0 1 0 0 1 1 1 1 Gasdermin family Guanylate_kin PF00625.16 KFM09372.1 - 7.7e-48 162.3 0.0 1.4e-47 161.4 0.0 1.5 1 0 0 1 1 1 1 Guanylate kinase L27 PF02828.11 KFM09372.1 - 5.6e-30 102.8 1.2 2.7e-15 55.7 0.0 2.9 3 0 0 3 3 3 2 L27 domain SH3_2 PF07653.12 KFM09372.1 - 1.2e-11 43.8 0.2 3.8e-11 42.2 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain PDZ PF00595.19 KFM09372.1 - 8.7e-11 41.8 1.1 1.8e-10 40.8 0.7 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) SH3_9 PF14604.1 KFM09372.1 - 1e-06 28.1 0.0 2.9e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 KFM09372.1 - 1.9e-06 27.1 0.1 5.2e-06 25.7 0.1 1.8 2 0 0 2 2 2 1 SH3 domain PDZ_2 PF13180.1 KFM09372.1 - 2.9e-05 23.8 0.1 8.6e-05 22.3 0.1 1.7 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.1 KFM09372.1 - 0.00088 19.0 0.1 0.011 15.4 0.1 2.7 2 1 0 2 2 2 1 Tricorn protease PDZ domain Hormone_3 PF00159.13 KFM09373.1 - 1.4e-19 69.7 2.3 2.3e-19 69.0 1.6 1.4 1 0 0 1 1 1 1 Pancreatic hormone peptide Pkinase PF00069.20 KFM09374.1 - 1.3e-18 67.0 0.0 3.7e-18 65.6 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain TUDOR PF00567.19 KFM09374.1 - 3.5e-17 62.3 0.2 9.8e-17 60.9 0.1 1.9 1 0 0 1 1 1 1 Tudor domain Pkinase_Tyr PF07714.12 KFM09374.1 - 1.9e-11 43.5 0.0 4.4e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase SNase PF00565.12 KFM09374.1 - 0.0025 18.0 0.2 0.0083 16.3 0.1 2.0 1 0 0 1 1 1 1 Staphylococcal nuclease homologue DUF4463 PF14703.1 KFM09374.1 - 0.23 12.0 6.0 0.34 11.4 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4463) ALMT PF11744.3 KFM09374.1 - 1.2 7.6 4.4 2.7 6.5 0.6 2.3 2 0 0 2 2 2 0 Aluminium activated malate transporter DivIC PF04977.10 KFM09374.1 - 4.1 6.9 11.4 1 8.8 3.5 2.9 2 0 0 2 2 2 0 Septum formation initiator DUF4475 PF14753.1 KFM09375.1 - 1.2e-94 315.4 5.3 1.5e-94 315.0 3.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4475) DUF4525 PF15027.1 KFM09376.1 - 9.8e-75 248.6 0.3 1.1e-74 248.5 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4525) DUF2897 PF11446.3 KFM09376.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) RRM_1 PF00076.17 KFM09377.1 - 3.8e-20 71.2 0.0 5.2e-20 70.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM09377.1 - 1.1e-15 57.2 0.0 1.7e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM09377.1 - 1.1e-09 38.0 0.0 1.5e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1777 PF08648.7 KFM09377.1 - 0.11 12.1 52.4 0.024 14.3 24.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 KFM09377.1 - 0.79 8.1 8.5 0.87 7.9 5.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Zip PF02535.17 KFM09377.1 - 3.5 6.5 9.6 4.5 6.1 6.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter KH_1 PF00013.24 KFM09378.1 - 5.7e-56 186.0 12.7 2.5e-14 52.6 0.1 4.7 5 0 0 5 5 5 4 KH domain KH_3 PF13014.1 KFM09378.1 - 5.7e-38 127.9 12.6 4.9e-09 35.6 0.0 4.8 4 0 0 4 4 4 4 KH domain RRM_1 PF00076.17 KFM09378.1 - 8.3e-17 60.5 0.0 9.3e-09 34.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_2 PF07650.12 KFM09378.1 - 4.7e-16 58.1 6.4 0.0018 17.8 0.1 4.6 4 0 0 4 4 4 4 KH domain KH_4 PF13083.1 KFM09378.1 - 1.2e-14 53.7 0.5 0.0012 18.4 0.0 4.7 4 0 0 4 4 4 4 KH domain RRM_6 PF14259.1 KFM09378.1 - 2.9e-14 52.7 0.0 1.1e-05 25.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM09378.1 - 4.6e-10 39.1 0.1 7.1e-07 28.9 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_5 PF13184.1 KFM09378.1 - 3.4e-08 33.1 2.6 0.24 11.2 0.1 4.5 4 0 0 4 4 4 3 NusA-like KH domain SLS PF14611.1 KFM09378.1 - 0.035 13.5 7.7 2.7 7.3 0.0 3.5 3 1 1 4 4 4 0 Mitochondrial inner-membrane-bound regulator DUF4041 PF13250.1 KFM09378.1 - 0.12 11.9 1.0 0.26 10.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) Evr1_Alr PF04777.8 KFM09378.1 - 0.16 11.8 0.1 0.82 9.6 0.0 2.2 2 0 0 2 2 2 0 Erv1 / Alr family LcrG PF07216.7 KFM09378.1 - 0.17 11.9 3.0 1.9 8.5 0.8 2.7 2 0 0 2 2 2 0 LcrG protein Oligomerisation PF02410.10 KFM09379.1 - 1.4e-26 92.3 0.0 1.7e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Oligomerisation domain PKD PF00801.15 KFM09380.1 - 2.7e-09 36.6 0.4 3.4e-08 33.1 0.2 2.8 3 0 0 3 3 3 1 PKD domain MMS22L_C PF14911.1 KFM09381.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, C-terminal Pox_A12 PF04651.8 KFM09381.1 - 8 6.5 7.2 0.7 9.9 0.3 2.2 2 0 0 2 2 2 0 Poxvirus A12 protein Kelch_1 PF01344.20 KFM09382.1 - 2.7e-44 148.4 12.3 2.6e-13 49.2 0.3 5.7 6 0 0 6 6 6 5 Kelch motif BACK PF07707.10 KFM09382.1 - 4.1e-34 116.4 1.0 4.9e-33 113.0 0.1 2.7 3 0 0 3 3 3 1 BTB And C-terminal Kelch Kelch_6 PF13964.1 KFM09382.1 - 4.3e-30 102.6 8.8 3.1e-09 36.5 0.0 6.4 1 1 5 6 6 6 4 Kelch motif BTB PF00651.26 KFM09382.1 - 5.2e-29 100.4 1.2 5.2e-29 100.4 0.8 1.9 2 0 0 2 2 2 1 BTB/POZ domain Kelch_4 PF13418.1 KFM09382.1 - 3.7e-25 87.4 1.0 4.6e-08 32.6 0.0 6.3 5 1 1 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.10 KFM09382.1 - 2.2e-21 74.7 6.2 2.8e-06 26.8 0.1 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.1 KFM09382.1 - 2.3e-16 59.4 0.9 1.4e-05 25.1 0.0 5.9 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 KFM09382.1 - 4e-10 39.4 3.0 0.0086 16.0 0.0 5.2 5 0 0 5 5 5 3 Kelch motif Glyoxal_oxid_N PF07250.6 KFM09382.1 - 0.0012 17.9 2.0 0.0032 16.5 0.1 2.3 2 1 1 3 3 3 1 Glyoxal oxidase N-terminus UvrD-helicase PF00580.16 KFM09382.1 - 0.085 12.1 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Hyccin PF09790.4 KFM09383.1 - 8.5e-137 455.1 0.7 1.2e-136 454.5 0.5 1.2 1 0 0 1 1 1 1 Hyccin IL6 PF00489.12 KFM09384.1 - 1.4e-36 125.3 1.8 1.6e-36 125.2 1.2 1.0 1 0 0 1 1 1 1 Interleukin-6/G-CSF/MGF family Bac_GDH PF05088.7 KFM09384.1 - 0.054 10.8 0.6 0.068 10.5 0.4 1.0 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase RasGEF PF00617.14 KFM09385.1 - 4.6e-63 212.3 3.5 4.9e-63 212.2 1.6 1.7 2 0 0 2 2 2 1 RasGEF domain DEP PF00610.16 KFM09385.1 - 3.1e-15 55.6 0.1 8.2e-15 54.3 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RasGEF_N PF00618.15 KFM09385.1 - 1.8e-09 37.6 1.0 1.8e-09 37.6 0.7 2.0 2 0 0 2 2 2 1 RasGEF N-terminal motif RA PF00788.18 KFM09385.1 - 0.00032 21.1 0.2 0.0018 18.7 0.1 2.4 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain Gp58 PF07902.6 KFM09385.1 - 0.066 11.4 0.0 0.1 10.8 0.0 1.1 1 0 0 1 1 1 0 gp58-like protein zf-4CXXC_R1 PF10497.4 KFM09386.1 - 4.1e-40 136.1 10.1 6.8e-40 135.4 7.0 1.4 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 EF-1_beta_acid PF10587.4 KFM09386.1 - 0.025 14.7 1.1 0.025 14.7 0.7 3.4 3 0 0 3 3 3 0 Eukaryotic elongation factor 1 beta central acidic region Dynein_heavy PF03028.10 KFM09387.1 - 1.1e-82 278.2 0.0 1.2e-82 278.1 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor zf-H2C2_2 PF13465.1 KFM09388.1 - 2e-16 59.3 8.7 2.6e-09 36.9 2.0 4.8 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFM09388.1 - 1.6e-13 50.1 30.4 2.6e-06 27.4 0.7 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM09388.1 - 1.9e-09 37.1 27.5 0.00013 22.0 1.0 3.7 4 0 0 4 4 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM09388.1 - 0.00058 19.9 6.3 0.9 9.7 0.9 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding RRN7 PF11781.3 KFM09388.1 - 0.1 12.1 9.3 1.2 8.7 0.1 3.4 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 Zn_Tnp_IS1 PF03811.8 KFM09388.1 - 0.13 11.7 7.6 1.3 8.5 1.5 2.6 2 0 0 2 2 2 0 InsA N-terminal domain zf-RING_3 PF14369.1 KFM09388.1 - 0.61 10.1 4.3 17 5.5 0.6 2.7 2 0 0 2 2 2 0 zinc-finger zf-met PF12874.2 KFM09388.1 - 1.1 9.5 5.5 15 5.9 0.9 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zinc_ribbon_4 PF13717.1 KFM09388.1 - 1.6 8.5 5.5 2.6 7.7 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2_6 PF13912.1 KFM09388.1 - 2 8.4 23.6 0.13 12.1 0.6 3.9 5 0 0 5 5 5 0 C2H2-type zinc finger zinc_ribbon_5 PF13719.1 KFM09388.1 - 3.1 7.4 6.3 2.9 7.5 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain Elf1 PF05129.8 KFM09388.1 - 4.2 7.1 7.0 0.72 9.5 1.6 2.0 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-BED PF02892.10 KFM09388.1 - 8.2 6.2 17.1 3.1 7.6 1.1 3.2 1 1 2 3 3 3 0 BED zinc finger zf-Di19 PF05605.7 KFM09388.1 - 8.5 6.5 15.0 0.56 10.3 2.8 3.5 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Integrin_beta PF00362.13 KFM09391.1 - 3.3e-137 457.8 0.2 3.3e-137 457.8 0.2 1.8 2 0 0 2 2 2 1 Integrin, beta chain EGF_2 PF07974.8 KFM09391.1 - 1.3e-06 28.4 34.5 0.00015 21.8 9.4 5.7 5 1 0 5 5 5 3 EGF-like domain Death PF00531.17 KFM09394.1 - 2.2e-06 27.3 1.8 0.042 13.6 0.1 3.1 1 1 2 3 3 3 2 Death domain SH3_2 PF07653.12 KFM09394.1 - 4.8e-05 22.7 0.2 9e-05 21.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain ZU5 PF00791.15 KFM09394.1 - 0.00059 19.4 0.1 0.0013 18.3 0.0 1.6 1 0 0 1 1 1 1 ZU5 domain DUF1446 PF07287.6 KFM09394.1 - 0.036 12.5 0.0 0.059 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1446) Chs3p PF12271.3 KFM09396.1 - 0.0078 15.2 0.8 0.012 14.6 0.6 1.3 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit ABC_membrane_3 PF13748.1 KFM09396.1 - 0.1 11.6 0.6 0.21 10.6 0.4 1.5 1 0 0 1 1 1 0 ABC transporter transmembrane region DUF4131 PF13567.1 KFM09396.1 - 6.5 6.1 8.0 0.69 9.3 2.3 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) S1 PF00575.18 KFM09397.1 - 0.029 14.4 0.0 0.083 12.9 0.0 1.8 1 0 0 1 1 1 0 S1 RNA binding domain DUF913 PF06025.7 KFM09397.1 - 7.4 5.2 12.0 1.7 7.3 6.0 1.6 1 1 1 2 2 2 0 Domain of Unknown Function (DUF913) HLH PF00010.21 KFM09398.1 - 3.6e-17 61.8 0.7 3.6e-17 61.8 0.5 1.6 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Tom37_C PF11801.3 KFM09398.1 - 0.059 13.2 0.0 0.074 12.9 0.0 1.0 1 0 0 1 1 1 0 Tom37 C-terminal domain Dor1 PF04124.7 KFM09398.1 - 0.065 11.6 0.3 0.084 11.3 0.2 1.1 1 0 0 1 1 1 0 Dor1-like family Hist_deacetyl PF00850.14 KFM09399.1 - 2.1e-84 283.5 1.5 2.9e-84 283.0 0.0 2.0 2 0 0 2 2 2 1 Histone deacetylase domain HDAC4_Gln PF12203.3 KFM09399.1 - 1.5e-38 130.6 48.7 1.5e-38 130.6 33.8 4.2 5 0 0 5 5 5 1 Glutamine rich N terminal domain of histone deacetylase 4 U-box PF04564.10 KFM09399.1 - 0.57 10.1 4.3 6.4 6.8 0.1 3.5 3 0 0 3 3 3 0 U-box domain PAS_3 PF08447.6 KFM09400.1 - 1.1e-17 63.9 0.2 9.6e-12 44.8 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS PF00989.19 KFM09400.1 - 1.6e-13 50.4 1.8 1.4e-11 44.2 0.0 3.3 3 0 0 3 3 3 1 PAS fold PAS_11 PF14598.1 KFM09400.1 - 2.1e-13 50.1 2.8 4.2e-10 39.5 0.0 3.3 3 0 0 3 3 3 2 PAS domain PAS_9 PF13426.1 KFM09400.1 - 1.1e-06 28.9 0.4 0.04 14.2 0.0 2.9 3 0 0 3 3 3 2 PAS domain HLH PF00010.21 KFM09400.1 - 2.1e-05 24.1 0.2 4.8e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_4 PF08448.5 KFM09400.1 - 0.0026 17.7 1.7 0.084 12.9 0.0 3.1 3 0 0 3 3 3 1 PAS fold Thioredoxin_7 PF13899.1 KFM09401.1 - 4.1e-26 90.8 0.2 7.9e-26 89.8 0.1 1.5 2 0 0 2 2 2 1 Thioredoxin-like Thioredox_DsbH PF03190.10 KFM09401.1 - 1.6e-06 27.9 0.1 2.2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_2 PF13098.1 KFM09401.1 - 2.5e-05 24.4 0.4 6.8e-05 23.0 0.3 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KFM09402.1 - 5.4e-25 87.2 0.0 1e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Tetraspannin PF00335.15 KFM09403.1 - 1.8e-20 73.2 14.2 2.3e-20 72.8 9.8 1.1 1 0 0 1 1 1 1 Tetraspanin family CcoS PF03597.10 KFM09403.1 - 0.051 13.0 1.6 0.051 13.0 1.1 3.3 4 0 0 4 4 4 0 Cytochrome oxidase maturation protein cbb3-type DUF3278 PF11683.3 KFM09403.1 - 0.1 12.6 0.9 0.13 12.2 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) GAPT PF11770.3 KFM09403.1 - 0.49 10.0 3.8 0.23 11.0 0.9 1.8 1 1 1 2 2 2 0 GRB2-binding adapter (GAPT) EPV_E5 PF08135.6 KFM09403.1 - 0.9 9.5 8.6 2.8 7.9 5.9 1.9 1 0 0 1 1 1 0 Major transforming protein E5 family DUF843 PF05814.6 KFM09403.1 - 2.9 7.7 7.1 6.7 6.5 4.9 1.6 1 1 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) DUF2207 PF09972.4 KFM09403.1 - 5.6 5.4 5.1 5.2 5.5 2.9 1.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF4131 PF13567.1 KFM09403.1 - 9.8 5.5 10.0 8 5.8 5.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) W2 PF02020.13 KFM09404.1 - 2e-23 82.1 4.0 2e-23 82.1 2.7 3.0 3 1 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon DIL PF01843.14 KFM09404.1 - 0.0065 16.3 6.0 7.3 6.5 0.1 4.5 4 1 1 5 5 5 2 DIL domain Ank PF00023.25 KFM09405.1 - 1.3e-16 59.5 1.8 3e-09 36.2 0.2 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 KFM09405.1 - 1.7e-16 60.2 0.8 5e-15 55.6 0.2 2.7 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFM09405.1 - 3.8e-15 55.5 0.6 4.4e-09 36.3 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFM09405.1 - 5.5e-14 52.2 0.3 5.9e-08 33.0 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM09405.1 - 2.9e-13 48.6 0.4 1.5e-08 34.0 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat zf-MYND PF01753.13 KFM09405.1 - 1.9e-09 37.2 12.3 1.9e-09 37.2 8.6 2.4 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.1 KFM09405.1 - 0.56 10.1 5.0 1.8 8.4 3.5 1.9 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Sec62 PF03839.11 KFM09405.1 - 0.96 8.8 7.2 1.4 8.2 5.0 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 ATP-synt_E PF05680.7 KFM09405.1 - 0.97 9.4 5.6 1.7 8.6 3.9 1.4 1 0 0 1 1 1 0 ATP synthase E chain CMV_1a PF12467.3 KFM09405.1 - 2.4 8.4 7.6 4.2 7.7 5.3 1.3 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family Trypan_PARP PF05887.6 KFM09405.1 - 3.6 7.4 10.1 7.9 6.2 7.0 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) LRR_4 PF12799.2 KFM09406.1 - 2.7e-16 58.7 15.9 1.9e-06 27.3 0.3 3.3 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 KFM09406.1 - 1.5e-14 53.9 2.4 5.9e-13 48.7 0.9 2.0 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.1 KFM09406.1 - 3.4e-13 49.1 12.4 1.2e-09 37.8 6.1 2.3 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 KFM09406.1 - 2.9e-08 32.6 12.5 0.077 13.0 0.2 5.4 5 0 0 5 5 5 4 Leucine Rich Repeat LRR_7 PF13504.1 KFM09406.1 - 1.2e-06 27.7 12.2 0.15 12.3 0.3 5.6 5 0 0 5 5 5 3 Leucine rich repeat LRR_6 PF13516.1 KFM09406.1 - 0.016 15.2 13.1 0.25 11.5 0.5 4.4 3 1 1 4 4 4 0 Leucine Rich repeat Sclerostin PF05463.6 KFM09407.1 - 6.3e-101 335.8 5.9 7.1e-101 335.7 4.1 1.0 1 0 0 1 1 1 1 Sclerostin (SOST) Cys_knot PF00007.17 KFM09407.1 - 3.5e-05 23.8 7.6 0.00018 21.5 5.3 1.9 1 1 0 1 1 1 1 Cystine-knot domain DAN PF03045.10 KFM09407.1 - 5.4e-05 22.6 1.6 9.6e-05 21.7 1.1 1.4 1 0 0 1 1 1 1 DAN domain DUF977 PF06163.6 KFM09407.1 - 0.053 13.2 0.4 0.095 12.4 0.3 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) IspD PF01128.14 KFM09408.1 - 3.6e-29 101.8 0.0 7.2e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Thioredoxin_8 PF13905.1 KFM09408.1 - 0.017 15.1 0.6 0.1 12.7 0.1 2.4 2 0 0 2 2 2 0 Thioredoxin-like Macoilin PF09726.4 KFM09409.1 - 0.14 10.4 2.2 0.1 10.8 1.5 1.1 1 0 0 1 1 1 0 Transmembrane protein Zip PF02535.17 KFM09409.1 - 0.14 11.1 10.8 0.15 11.0 7.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 KFM09409.1 - 3 7.1 14.1 3.9 6.7 9.8 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Innate_immun PF12782.2 KFM09409.1 - 3.7 6.6 11.9 4.6 6.3 8.2 1.2 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family SNF2_N PF00176.18 KFM09410.1 - 1e-78 264.1 0.2 1e-78 264.1 0.2 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain BRK PF07533.11 KFM09410.1 - 1.8e-18 65.6 0.0 3.3e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 BRK domain HSA PF07529.8 KFM09410.1 - 3.4e-18 65.1 14.4 3.4e-18 65.1 10.0 3.1 3 0 0 3 3 3 1 HSA Helicase_C PF00271.26 KFM09410.1 - 3.2e-16 58.9 0.0 3.9e-15 55.4 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain QLQ PF08880.6 KFM09410.1 - 1.2e-15 56.6 2.8 3.5e-15 55.1 2.0 1.9 1 0 0 1 1 1 1 QLQ ResIII PF04851.10 KFM09410.1 - 3.8e-06 26.8 0.0 3.8e-06 26.8 0.0 3.6 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Pyr_redox_2 PF07992.9 KFM09411.1 - 9.6e-36 123.5 0.0 5.4e-35 121.0 0.0 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFM09411.1 - 2.9e-18 66.0 2.8 1.8e-14 53.8 0.2 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 KFM09411.1 - 1.6e-15 56.3 0.2 3.7e-15 55.2 0.2 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DAO PF01266.19 KFM09411.1 - 2.7e-11 42.9 0.9 0.00026 20.0 0.0 3.2 3 0 0 3 3 3 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KFM09411.1 - 7e-10 39.2 0.4 8e-05 22.7 0.0 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFM09411.1 - 6.1e-09 34.8 3.0 0.0027 16.2 0.1 4.1 3 1 1 4 4 4 2 HI0933-like protein NAD_binding_8 PF13450.1 KFM09411.1 - 8.8e-08 32.0 0.2 0.00029 20.7 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Rieske_2 PF13806.1 KFM09411.1 - 3e-07 30.0 0.0 8e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Lycopene_cycl PF05834.7 KFM09411.1 - 2.1e-06 26.9 0.6 0.045 12.6 0.0 3.1 2 1 1 3 3 3 2 Lycopene cyclase protein FAD_binding_3 PF01494.14 KFM09411.1 - 2.5e-06 26.8 1.0 0.0013 17.8 0.0 3.1 3 0 0 3 3 3 1 FAD binding domain FAD_binding_2 PF00890.19 KFM09411.1 - 4.8e-06 25.6 3.6 0.0013 17.7 0.0 3.8 3 1 1 4 4 4 1 FAD binding domain Thi4 PF01946.12 KFM09411.1 - 0.0001 21.4 0.9 0.16 11.0 0.0 2.8 3 0 0 3 3 3 2 Thi4 family NAD_binding_9 PF13454.1 KFM09411.1 - 0.00017 21.3 0.3 1 9.1 0.0 3.6 3 1 1 4 4 4 2 FAD-NAD(P)-binding GIDA PF01134.17 KFM09411.1 - 0.00018 20.5 3.4 0.82 8.4 0.0 3.8 3 1 1 4 4 4 2 Glucose inhibited division protein A K_oxygenase PF13434.1 KFM09411.1 - 0.0016 17.4 0.0 0.018 13.9 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.13 KFM09411.1 - 0.0025 17.7 0.1 1.9 8.4 0.0 2.7 2 1 0 2 2 2 1 TrkA-N domain Shikimate_DH PF01488.15 KFM09411.1 - 0.0027 17.8 0.1 0.1 12.7 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Malic_M PF03949.10 KFM09411.1 - 0.0037 16.8 0.0 0.015 14.8 0.0 2.0 3 0 0 3 3 2 1 Malic enzyme, NAD binding domain ThiF PF00899.16 KFM09411.1 - 0.0044 16.8 3.2 0.25 11.1 0.0 3.0 3 0 0 3 3 3 1 ThiF family 3HCDH_N PF02737.13 KFM09411.1 - 0.013 15.2 0.1 0.55 9.8 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 KFM09411.1 - 0.032 13.3 0.1 2.1 7.4 0.0 3.0 2 1 1 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KFM09411.1 - 0.035 13.4 0.6 1.4 8.2 0.1 2.7 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 KFM09411.1 - 0.045 13.1 0.0 3.2 7.2 0.0 2.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DUF1188 PF06690.6 KFM09411.1 - 0.051 12.7 0.0 0.48 9.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) Reductase_C PF14759.1 KFM09411.1 - 0.054 13.8 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 Reductase C-terminal NAD_binding_7 PF13241.1 KFM09411.1 - 0.072 13.3 1.2 2.8 8.2 0.0 2.9 2 1 0 3 3 3 0 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 KFM09411.1 - 0.074 12.7 0.0 10 5.7 0.0 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Trp_halogenase PF04820.9 KFM09411.1 - 0.088 11.4 1.8 2.5 6.6 0.1 2.7 2 1 1 3 3 3 0 Tryptophan halogenase Transmemb_17 PF09799.4 KFM09412.1 - 5.9e-19 68.4 3.0 6.5e-19 68.2 2.1 1.0 1 0 0 1 1 1 1 Predicted membrane protein P2X_receptor PF00864.14 KFM09413.1 - 2.4e-94 316.1 0.3 2.6e-94 315.9 0.2 1.0 1 0 0 1 1 1 1 ATP P2X receptor LRR_6 PF13516.1 KFM09414.1 - 2e-21 73.6 3.4 0.0055 16.6 0.0 6.2 6 0 0 6 6 6 5 Leucine Rich repeat LRR_1 PF00560.28 KFM09414.1 - 6.1e-08 31.6 0.0 1 9.6 0.0 5.5 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_4 PF12799.2 KFM09414.1 - 3.7e-07 29.6 0.0 0.017 14.7 0.0 3.9 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 KFM09414.1 - 1.5e-06 27.4 0.3 15 6.2 0.0 5.6 5 0 0 5 5 5 2 Leucine rich repeat LRR_8 PF13855.1 KFM09414.1 - 0.0089 15.7 1.1 4 7.2 0.1 3.6 2 2 1 3 3 3 2 Leucine rich repeat DUF796 PF05638.7 KFM09414.1 - 0.035 14.0 0.0 0.63 10.0 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF796) AA_permease_2 PF13520.1 KFM09415.1 - 7.4e-49 166.4 35.8 7.4e-49 166.4 24.8 2.1 2 0 0 2 2 2 1 Amino acid permease AA_permease PF00324.16 KFM09415.1 - 1.6e-40 138.8 43.4 6.9e-40 136.7 23.8 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease_C PF13906.1 KFM09415.1 - 7.2e-21 73.8 8.3 7.2e-21 73.8 5.7 4.2 4 1 0 4 4 4 1 C-terminus of AA_permease IncA PF04156.9 KFM09415.1 - 0.48 9.9 0.0 0.48 9.9 0.0 4.2 4 0 0 4 4 4 0 IncA protein DGCR6 PF07324.6 KFM09416.1 - 1.1e-50 171.8 5.6 1.2e-50 171.7 3.9 1.0 1 0 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein DUF2458 PF10454.4 KFM09416.1 - 0.03 14.2 2.0 0.037 13.9 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) DUF3781 PF12636.2 KFM09416.1 - 0.14 12.1 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) UreD PF01774.12 KFM09416.1 - 0.14 11.5 0.2 0.17 11.3 0.1 1.1 1 0 0 1 1 1 0 UreD urease accessory protein Pro_dh PF01619.13 KFM09417.1 - 9.7e-83 277.7 0.4 1.2e-82 277.4 0.3 1.1 1 0 0 1 1 1 1 Proline dehydrogenase DUF4093 PF13331.1 KFM09417.1 - 0.014 15.5 0.2 0.39 10.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4093) His_Phos_1 PF00300.17 KFM09417.1 - 0.028 14.5 0.1 0.054 13.5 0.1 1.6 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) HrpB2 PF09487.5 KFM09417.1 - 0.069 13.3 0.2 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) YscJ_FliF PF01514.12 KFM09417.1 - 0.11 11.6 0.0 0.26 10.3 0.0 1.6 1 0 0 1 1 1 0 Secretory protein of YscJ/FliF family zf-RanBP PF00641.13 KFM09418.1 - 9.4e-09 34.2 1.9 1.7e-08 33.3 1.3 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Maf1 PF09174.5 KFM09419.1 - 2.4e-67 226.2 0.1 3e-67 225.9 0.1 1.1 1 0 0 1 1 1 1 Maf1 regulator Integrin_B_tail PF07965.7 KFM09420.1 - 6e-21 74.6 7.3 6e-21 74.6 5.1 2.4 2 1 1 3 3 3 1 Integrin beta tail domain EGF_2 PF07974.8 KFM09420.1 - 1.8e-08 34.3 35.6 5.5e-07 29.6 11.2 4.3 5 0 0 5 5 5 2 EGF-like domain Helicase_C PF00271.26 KFM09421.1 - 2.3e-19 69.0 0.0 9.2e-19 67.0 0.0 1.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain 7tm_1 PF00001.16 KFM09422.1 - 3.3e-79 265.6 11.4 4.4e-79 265.2 7.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM09422.1 - 8.4e-07 28.4 13.7 1.7e-06 27.3 9.5 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM09422.1 - 1.6e-06 27.4 14.8 2.7e-06 26.6 10.3 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx CytochromB561_N PF09786.4 KFM09422.1 - 0.3 9.4 3.9 3 6.2 1.6 2.0 2 0 0 2 2 2 0 Cytochrome B561, N terminal BRICHOS PF04089.9 KFM09424.1 - 1.9e-19 69.3 0.0 3.2e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 BRICHOS domain Tetraspannin PF00335.15 KFM09425.1 - 4.8e-30 104.4 5.4 5.5e-30 104.2 3.7 1.0 1 0 0 1 1 1 1 Tetraspanin family FixQ PF05545.6 KFM09425.1 - 0.022 14.3 0.3 0.039 13.5 0.2 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ FeoB_C PF07664.7 KFM09425.1 - 0.046 13.1 3.2 0.077 12.4 0.1 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus DUF4190 PF13828.1 KFM09425.1 - 0.055 13.0 3.9 0.37 10.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) DUF307 PF03733.8 KFM09425.1 - 1 9.8 4.4 1.1 9.6 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF307) DUF4174 PF13778.1 KFM09426.1 - 5.8e-28 97.3 0.0 7.8e-28 96.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4174) Sushi PF00084.15 KFM09426.1 - 1.2e-25 89.6 23.6 3.7e-11 43.2 4.8 3.7 3 0 0 3 3 3 3 Sushi domain (SCR repeat) HYR PF02494.11 KFM09426.1 - 6.9e-18 64.4 0.0 1.1e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 HYR domain cEGF PF12662.2 KFM09426.1 - 7 6.3 20.9 1.4 8.6 3.0 4.0 3 1 0 3 3 3 0 Complement Clr-like EGF-like C2 PF00168.25 KFM09427.1 - 2.7e-42 142.4 0.1 7.1e-21 73.8 0.0 2.2 2 0 0 2 2 2 2 C2 domain SRP9-21 PF05486.7 KFM09427.1 - 3.2 7.5 5.5 7.9 6.2 0.3 2.4 2 1 0 2 2 2 0 Signal recognition particle 9 kDa protein (SRP9) Met_10 PF02475.11 KFM09428.1 - 6.9e-30 104.1 0.0 8.8e-30 103.7 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 KFM09428.1 - 6.8e-08 32.5 0.9 1.9e-07 31.0 0.3 1.9 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KFM09428.1 - 4.2e-05 23.0 0.0 6.9e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 KFM09428.1 - 0.0007 20.1 0.0 0.0017 18.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.10 KFM09428.1 - 0.054 12.8 0.0 0.097 12.0 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 CSTF2_hinge PF14327.1 KFM09429.1 - 4.8e-32 109.8 2.5 9.6e-32 108.9 1.7 1.5 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.1 KFM09429.1 - 3.2e-22 77.5 6.3 3.2e-22 77.5 4.4 1.9 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_1 PF00076.17 KFM09429.1 - 5.9e-10 38.6 0.0 1e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM09429.1 - 0.00079 19.3 0.0 0.0018 18.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM09429.1 - 0.0027 17.5 0.0 0.0056 16.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAD_binding_6 PF08030.7 KFM09430.1 - 5.8e-31 107.5 0.0 1.3e-30 106.3 0.0 1.6 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KFM09430.1 - 2.9e-23 81.7 0.0 5.3e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KFM09430.1 - 2.1e-22 79.5 6.2 5e-22 78.3 4.3 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KFM09430.1 - 2e-06 27.8 0.0 3.4e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KFM09430.1 - 0.0034 17.9 0.0 0.024 15.2 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Tic20 PF09685.5 KFM09430.1 - 0.011 15.6 0.5 0.087 12.8 0.1 2.3 2 0 0 2 2 2 0 Tic20-like protein XK-related PF09815.4 KFM09431.1 - 6.2e-73 245.6 14.6 1.1e-72 244.8 10.1 1.4 1 1 0 1 1 1 1 XK-related protein HAD PF12710.2 KFM09432.1 - 1.4e-18 67.7 0.4 6.6e-18 65.5 0.3 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KFM09432.1 - 2.5e-16 59.4 0.0 2.5e-16 59.4 0.0 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 KFM09432.1 - 2.6e-12 46.5 0.0 9.9e-12 44.6 0.0 2.1 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 KFM09432.1 - 3.2e-11 44.0 0.6 6.6e-09 36.4 0.4 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFM09432.1 - 0.0083 15.7 0.0 0.48 9.9 0.0 2.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RhoGEF PF00621.15 KFM09433.1 - 8.3e-40 136.5 0.5 8.3e-40 136.5 0.3 2.8 3 0 0 3 3 3 2 RhoGEF domain CRAL_TRIO_2 PF13716.1 KFM09433.1 - 3.5e-15 56.2 0.0 9.9e-15 54.7 0.0 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain PH PF00169.24 KFM09433.1 - 7.1e-05 22.9 0.1 0.00017 21.7 0.1 1.6 1 0 0 1 1 1 1 PH domain Spectrin PF00435.16 KFM09433.1 - 0.0078 16.4 1.1 0.0078 16.4 0.7 4.5 5 1 0 5 5 5 2 Spectrin repeat DUF948 PF06103.6 KFM09433.1 - 0.18 11.6 0.8 2.7 7.9 0.1 3.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Trypsin PF00089.21 KFM09434.1 - 3.7e-66 222.8 0.7 4.9e-66 222.4 0.5 1.2 1 0 0 1 1 1 1 Trypsin Gla PF00594.15 KFM09434.1 - 2.9e-18 65.2 5.1 4.7e-18 64.5 3.5 1.4 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain FXa_inhibition PF14670.1 KFM09434.1 - 1e-11 44.7 6.8 1e-11 44.7 4.7 3.1 3 1 0 3 3 3 2 Coagulation Factor Xa inhibitory site EGF PF00008.22 KFM09434.1 - 2e-08 33.9 16.3 2.2e-07 30.7 3.3 2.8 2 0 0 2 2 2 2 EGF-like domain cEGF PF12662.2 KFM09434.1 - 8.6e-08 31.6 7.7 9.1e-05 22.0 0.3 2.8 2 0 0 2 2 2 2 Complement Clr-like EGF-like Trypsin_2 PF13365.1 KFM09434.1 - 4.4e-06 26.6 0.0 1.1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.6 KFM09434.1 - 0.00034 19.9 0.0 0.00056 19.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Haemagg_act PF05860.8 KFM09434.1 - 0.088 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 haemagglutination activity domain EGF_CA PF07645.10 KFM09434.1 - 0.092 12.7 19.4 0.92 9.5 8.8 3.2 2 1 0 2 2 2 0 Calcium-binding EGF domain EGF_3 PF12947.2 KFM09434.1 - 0.19 11.7 22.7 1.9 8.4 4.9 2.9 2 0 0 2 2 2 0 EGF domain hEGF PF12661.2 KFM09434.1 - 1.9 8.7 13.8 0.36 10.9 2.5 3.2 3 0 0 3 3 2 0 Human growth factor-like EGF FGF PF00167.13 KFM09435.1 - 9.3e-45 151.3 0.3 1.2e-44 150.9 0.2 1.1 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.8 KFM09435.1 - 0.00036 20.6 0.1 0.0036 17.3 0.0 2.1 1 1 1 2 2 2 1 Fascin domain Epimerase PF01370.16 KFM09436.1 - 6.5e-46 156.6 0.0 8.3e-46 156.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DDE_1 PF03184.14 KFM09437.1 - 3.4e-23 81.9 0.0 4.4e-22 78.2 0.0 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 KFM09437.1 - 4e-10 39.3 0.4 8.9e-10 38.2 0.3 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain EF1_GNE PF00736.14 KFM09438.1 - 1.9e-35 120.4 1.4 4.2e-35 119.3 1.0 1.6 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 KFM09438.1 - 4.4e-12 45.9 7.7 4.4e-12 45.9 5.4 2.2 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region Striatin PF08232.7 KFM09438.1 - 0.004 17.4 1.1 0.004 17.4 0.7 1.9 2 0 0 2 2 2 1 Striatin family MinC_N PF05209.8 KFM09438.1 - 0.09 12.5 0.0 0.29 10.9 0.0 1.8 2 0 0 2 2 2 0 Septum formation inhibitor MinC, N-terminal domain NAPRTase PF04095.11 KFM09439.1 - 1.6e-18 66.9 0.0 5.1e-09 35.7 0.0 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family UCH PF00443.24 KFM09440.1 - 1.2e-05 24.6 4.2 0.00016 20.8 2.9 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Hrs_helical PF12210.3 KFM09440.1 - 0.0023 18.1 0.0 0.0038 17.4 0.0 1.4 1 0 0 1 1 1 1 Hepatocyte growth factor-regulated tyrosine kinase substrate Sep15_SelM PF08806.6 KFM09440.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Sep15/SelM redox domain BRO1 PF03097.13 KFM09442.1 - 1.3e-113 379.6 0.2 2.1e-113 378.9 0.1 1.3 1 0 0 1 1 1 1 BRO1-like domain HR1 PF02185.11 KFM09442.1 - 7e-16 57.7 3.8 1.5e-15 56.7 2.6 1.6 1 0 0 1 1 1 1 Hr1 repeat PDZ PF00595.19 KFM09442.1 - 9.1e-14 51.4 0.0 1.8e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM09442.1 - 2.5e-06 27.2 0.0 7.1e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 PDZ domain DUF1669 PF07894.7 KFM09442.1 - 0.003 16.8 0.0 0.009 15.2 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1669) Tricorn_PDZ PF14685.1 KFM09442.1 - 0.012 15.3 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 Tricorn protease PDZ domain Fmp27_WPPW PF10359.4 KFM09442.1 - 0.045 12.1 1.9 0.079 11.3 1.3 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4061 PF13270.1 KFM09442.1 - 0.52 10.4 4.8 1.3 9.1 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) Syntaxin-6_N PF09177.6 KFM09442.1 - 0.6 10.5 3.0 0.56 10.6 0.5 2.1 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Topoisom_I_N PF02919.10 KFM09443.1 - 1.3e-102 341.5 5.2 1.3e-102 341.5 3.6 3.7 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 KFM09443.1 - 2.8e-95 317.9 9.1 2.8e-95 317.9 6.3 2.2 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 KFM09443.1 - 1.2e-33 114.5 0.2 1.2e-33 114.5 0.1 2.7 2 0 0 2 2 2 1 C-terminal topoisomerase domain MRP-S23 PF10484.4 KFM09443.1 - 0.0035 17.2 1.5 0.0035 17.2 1.0 2.4 2 1 0 2 2 2 1 Mitochondrial ribosomal protein S23 Hanta_nucleocap PF00846.13 KFM09443.1 - 0.2 10.3 8.9 0.35 9.5 6.2 1.3 1 0 0 1 1 1 0 Hantavirus nucleocapsid protein UPAR_LY6 PF00021.16 KFM09444.1 - 3.3e-09 37.0 12.8 4.4e-09 36.6 8.9 1.2 1 0 0 1 1 1 1 u-PAR/Ly-6 domain Toxin_1 PF00087.16 KFM09444.1 - 0.32 11.4 12.5 0.72 10.2 8.5 1.8 1 1 0 1 1 1 0 Snake toxin UPAR_LY6 PF00021.16 KFM09445.1 - 1.2e-07 32.0 17.1 1.5e-07 31.7 11.9 1.1 1 0 0 1 1 1 1 u-PAR/Ly-6 domain Tombus_P19 PF03220.8 KFM09445.1 - 0.0093 15.3 0.1 0.011 15.1 0.1 1.0 1 0 0 1 1 1 1 Tombusvirus P19 core protein Toxin_1 PF00087.16 KFM09445.1 - 0.74 10.2 15.7 1.3 9.4 10.9 1.4 1 0 0 1 1 1 0 Snake toxin Inhibitor_I67 PF11405.3 KFM09445.1 - 4.5 7.4 11.1 16 5.6 0.1 2.9 1 1 1 2 2 2 0 Bromelain inhibitor VI DUF1644 PF07800.7 KFM09445.1 - 4.9 6.9 11.1 1.3e+02 2.3 7.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) UPAR_LY6 PF00021.16 KFM09446.1 - 1.6e-10 41.2 15.2 2e-10 40.9 10.5 1.1 1 0 0 1 1 1 1 u-PAR/Ly-6 domain Toxin_1 PF00087.16 KFM09446.1 - 0.015 15.6 13.7 0.028 14.7 9.5 1.5 1 1 0 1 1 1 0 Snake toxin UPAR_LY6 PF00021.16 KFM09447.1 - 2.7e-13 50.1 10.6 3.3e-13 49.8 7.3 1.1 1 0 0 1 1 1 1 u-PAR/Ly-6 domain Toxin_1 PF00087.16 KFM09447.1 - 0.0075 16.6 8.2 0.012 15.9 5.7 1.4 1 0 0 1 1 1 1 Snake toxin UPAR_LY6 PF00021.16 KFM09448.1 - 2.1e-06 28.0 12.8 2.7e-06 27.7 8.8 1.2 1 0 0 1 1 1 1 u-PAR/Ly-6 domain BAMBI PF06211.7 KFM09448.1 - 0.88 9.5 7.8 1.5 8.8 5.4 1.5 1 1 0 1 1 1 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain Activin_recp PF01064.18 KFM09448.1 - 2.2 8.9 12.7 9.5 6.9 8.8 1.9 1 1 0 1 1 1 0 Activin types I and II receptor domain UPAR_LY6 PF00021.16 KFM09449.1 - 0.00017 21.9 12.7 0.00023 21.5 8.8 1.2 1 0 0 1 1 1 1 u-PAR/Ly-6 domain BAMBI PF06211.7 KFM09449.1 - 1.4 8.9 8.5 1.9 8.5 5.9 1.1 1 0 0 1 1 1 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain Retrotrans_gag PF03732.12 KFM09450.1 - 0.00063 19.7 2.2 0.0012 18.8 0.3 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein Apolipoprotein PF01442.13 KFM09450.1 - 0.0049 16.3 2.0 0.012 15.1 0.5 1.9 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain HCR PF07111.7 KFM09450.1 - 0.032 12.2 0.3 0.045 11.7 0.2 1.1 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) DUF842 PF05811.8 KFM09450.1 - 0.053 12.9 0.4 0.2 11.0 0.2 2.0 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) SYCE1 PF15233.1 KFM09450.1 - 0.054 13.4 2.0 0.17 11.8 0.0 2.4 2 1 0 2 2 2 0 Synaptonemal complex central element protein 1 DUF327 PF03885.8 KFM09450.1 - 0.064 13.0 0.2 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF327) Ribonuc_2-5A PF06479.7 KFM09450.1 - 0.19 11.5 1.3 3.2 7.6 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease 2-5A 7tm_2 PF00002.19 KFM09451.1 - 3.8e-65 219.3 17.3 5.2e-65 218.9 12.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) TSP_1 PF00090.14 KFM09451.1 - 5.8e-50 167.1 87.3 2.4e-13 49.9 4.9 6.5 6 0 0 6 6 6 5 Thrombospondin type 1 domain DUF3497 PF12003.3 KFM09451.1 - 1.9e-43 148.3 0.2 2.6e-42 144.6 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3497) GPS PF01825.16 KFM09451.1 - 6.4e-12 45.3 0.5 6.4e-12 45.3 0.4 2.9 2 0 0 2 2 2 1 Latrophilin/CL-1-like GPS domain NDUF_B12 PF08122.7 KFM09451.1 - 0.035 13.8 0.2 0.096 12.4 0.1 1.7 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B12 subunit family DUF3422 PF11902.3 KFM09451.1 - 0.17 10.7 0.1 0.32 9.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3422) Syntaxin_2 PF14523.1 KFM09452.1 - 1.7e-21 76.1 9.3 1.7e-21 76.1 6.5 2.7 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 KFM09452.1 - 1.9e-19 69.1 8.7 1.9e-19 69.1 6.0 2.9 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 KFM09452.1 - 1.1e-06 28.7 5.9 1.1e-06 28.7 4.1 2.5 2 1 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 KFM09452.1 - 0.0068 15.9 18.7 0.024 14.1 4.4 2.6 2 1 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Talin_middle PF09141.5 KFM09452.1 - 0.017 14.7 5.9 0.37 10.4 0.7 2.6 2 1 0 2 2 2 0 Talin, middle domain DUF1664 PF07889.7 KFM09452.1 - 0.042 13.6 16.3 3.6 7.4 1.0 3.9 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) Cauli_AT PF03233.8 KFM09452.1 - 0.053 13.2 6.5 0.088 12.5 0.2 2.4 2 1 0 2 2 2 0 Aphid transmission protein NYD-SP28 PF14772.1 KFM09452.1 - 0.15 12.1 0.2 0.15 12.1 0.1 3.0 2 1 1 3 3 3 0 Sperm tail Enoyl_reductase PF12241.3 KFM09452.1 - 0.16 10.9 1.9 0.13 11.2 0.3 1.6 2 0 0 2 2 2 0 Trans-2-enoyl-CoA reductase catalytic region Fibritin_C PF07921.7 KFM09452.1 - 0.34 10.8 5.7 0.21 11.5 0.8 2.7 2 2 0 2 2 2 0 Fibritin C-terminal region Sin3_corepress PF08295.7 KFM09452.1 - 0.63 9.8 4.2 20 4.9 0.1 2.8 2 1 1 3 3 3 0 Sin3 family co-repressor DUF745 PF05335.8 KFM09452.1 - 0.65 9.4 13.1 0.37 10.2 1.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF745) IncA PF04156.9 KFM09452.1 - 0.81 9.2 22.2 2 7.9 6.1 2.6 2 1 0 2 2 2 0 IncA protein THOC7 PF05615.8 KFM09452.1 - 1 9.6 13.3 3.7 7.8 2.3 2.3 2 0 0 2 2 2 0 Tho complex subunit 7 Sipho_Gp157 PF05565.6 KFM09452.1 - 1.3 8.6 12.1 0.12 11.9 0.9 2.4 2 1 0 2 2 2 0 Siphovirus Gp157 Cluap1 PF10234.4 KFM09452.1 - 1.6 7.8 18.6 1.5 7.9 3.7 2.1 2 0 0 2 2 2 0 Clusterin-associated protein-1 MAT1 PF06391.8 KFM09452.1 - 2.5 7.6 13.5 1.3 8.5 2.0 2.2 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 TMPIT PF07851.8 KFM09452.1 - 2.8 6.9 9.9 2.7 6.9 0.9 2.1 2 0 0 2 2 2 0 TMPIT-like protein Laminin_II PF06009.7 KFM09452.1 - 3 7.5 17.6 2.1 8.0 2.6 3.3 2 1 0 2 2 2 0 Laminin Domain II SlyX PF04102.7 KFM09452.1 - 3.4 8.1 19.3 1.5 9.2 3.5 3.7 2 1 2 4 4 4 0 SlyX FUSC PF04632.7 KFM09452.1 - 4.1 5.7 7.0 0.41 9.0 0.7 1.8 2 0 0 2 2 2 0 Fusaric acid resistance protein family BRE1 PF08647.6 KFM09452.1 - 5.5 7.0 11.1 3.5 7.6 0.2 2.8 2 2 0 2 2 2 0 BRE1 E3 ubiquitin ligase Noelin-1 PF12308.3 KFM09452.1 - 6.3 6.6 7.7 0.88 9.4 0.9 2.6 2 2 1 3 3 3 0 Neurogenesis glycoprotein DUF4446 PF14584.1 KFM09452.1 - 6.6 6.5 14.3 13 5.5 1.2 3.6 2 2 2 4 4 4 0 Protein of unknown function (DUF4446) Reo_sigmaC PF04582.7 KFM09452.1 - 8.8 5.3 12.5 8.1 5.5 1.6 2.1 2 0 0 2 2 2 0 Reovirus sigma C capsid protein bZIP_2 PF07716.10 KFM09453.1 - 0.00068 19.4 5.3 0.0014 18.4 3.7 1.5 1 0 0 1 1 1 1 Basic region leucine zipper ATG16 PF08614.6 KFM09453.1 - 0.009 15.8 0.4 0.011 15.6 0.3 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DivIC PF04977.10 KFM09453.1 - 0.012 15.0 1.3 0.024 14.1 0.9 1.5 1 0 0 1 1 1 0 Septum formation initiator Phlebovirus_NSM PF07246.6 KFM09453.1 - 0.015 14.4 0.5 0.021 14.0 0.4 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M AKNA PF12443.3 KFM09453.1 - 0.02 14.9 0.5 0.035 14.1 0.3 1.6 1 1 1 2 2 2 0 AT-hook-containing transcription factor DUF1192 PF06698.6 KFM09453.1 - 0.049 13.4 2.9 0.14 11.9 2.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) TMF_DNA_bd PF12329.3 KFM09453.1 - 0.54 10.0 3.5 0.27 11.0 0.8 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding tRNA-synt_1g PF09334.6 KFM09454.1 - 3.9e-141 470.2 0.0 4.8e-141 469.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) WHEP-TRS PF00458.15 KFM09454.1 - 6.6e-17 60.9 5.8 1.4e-16 59.8 4.0 1.5 1 0 0 1 1 1 1 WHEP-TRS domain GST_C_3 PF14497.1 KFM09454.1 - 1.9e-07 31.4 0.2 1e-06 29.0 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1 PF00133.17 KFM09454.1 - 1.9e-07 29.4 0.2 0.00035 18.7 0.0 2.8 2 1 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) GST_C_2 PF13410.1 KFM09454.1 - 0.00017 21.3 0.1 0.00072 19.4 0.0 2.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Anticodon_1 PF08264.8 KFM09454.1 - 0.00051 19.8 0.0 0.0015 18.3 0.0 1.7 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA GST_C PF00043.20 KFM09454.1 - 0.00086 19.2 0.0 0.0029 17.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain RhoGAP PF00620.22 KFM09455.1 - 1.6e-38 131.6 0.1 2.4e-38 131.1 0.0 1.3 2 0 0 2 2 2 1 RhoGAP domain SYS1 PF09801.4 KFM09456.1 - 1.3e-37 128.9 3.5 1.4e-37 128.8 2.4 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Oxidored_q2 PF00420.19 KFM09456.1 - 0.45 10.1 4.4 1.9 8.1 3.2 1.8 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Tweety PF04906.8 KFM09456.1 - 4.1 5.7 6.7 0.1 10.9 0.3 1.4 2 0 0 2 2 2 0 Tweety Syndecan PF01034.15 KFM09457.1 - 4e-24 84.0 0.1 6.7e-24 83.3 0.1 1.3 1 0 0 1 1 1 1 Syndecan domain Herpes_gE PF02480.11 KFM09457.1 - 0.055 11.7 0.0 0.062 11.5 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Protocadherin PF08374.6 KFM09457.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Protocadherin BTD PF09270.5 KFM09458.1 - 1.8e-62 209.7 0.0 6.9e-62 207.8 0.0 1.9 2 0 0 2 2 2 1 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.6 KFM09458.1 - 9.8e-51 171.9 0.1 1.5e-50 171.2 0.0 1.3 1 0 0 1 1 1 1 LAG1, DNA binding TIG PF01833.19 KFM09458.1 - 1.6e-07 31.2 0.0 4.5e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 IPT/TIG domain VWA PF00092.23 KFM09459.1 - 3.3e-95 316.8 0.3 2.4e-48 164.2 0.0 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain FXa_inhibition PF14670.1 KFM09459.1 - 1e-31 108.7 62.0 1.9e-09 37.4 6.5 4.5 4 0 0 4 4 4 4 Coagulation Factor Xa inhibitory site VWA_2 PF13519.1 KFM09459.1 - 1.4e-30 106.6 0.0 3.2e-14 53.4 0.0 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain cEGF PF12662.2 KFM09459.1 - 4.5e-20 70.9 31.0 1.5e-06 27.7 1.4 4.9 4 0 0 4 4 4 4 Complement Clr-like EGF-like EGF_CA PF07645.10 KFM09459.1 - 1e-19 70.2 52.3 2.1e-07 30.8 4.2 4.4 4 0 0 4 4 4 4 Calcium-binding EGF domain EGF PF00008.22 KFM09459.1 - 1.5e-12 47.1 47.6 0.00033 20.5 4.0 4.7 4 0 0 4 4 4 4 EGF-like domain vWA-TerF-like PF10138.4 KFM09459.1 - 2.7e-09 37.1 0.8 0.00039 20.2 0.0 2.2 2 0 0 2 2 2 2 vWA found in TerF C terminus VWA_3 PF13768.1 KFM09459.1 - 6.2e-08 32.4 0.1 0.0094 15.6 0.0 2.5 2 1 0 2 2 2 2 von Willebrand factor type A domain Matrilin_ccoil PF10393.4 KFM09459.1 - 7.5e-08 31.6 1.2 2.4e-07 29.9 0.8 1.9 1 0 0 1 1 1 1 Trimeric coiled-coil oligomerisation domain of matrilin EGF_3 PF12947.2 KFM09459.1 - 4e-05 23.4 48.1 0.0075 16.2 3.9 4.8 4 0 0 4 4 4 2 EGF domain ClpB_D2-small PF10431.4 KFM09459.1 - 0.082 12.8 0.0 4.9 7.1 0.0 2.5 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein Ion_trans PF00520.26 KFM09460.1 - 7.7e-32 110.1 2.5 1.5e-31 109.2 0.4 2.0 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 KFM09460.1 - 2.7e-30 104.4 0.1 6e-30 103.3 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.11 KFM09460.1 - 3.8e-10 39.3 4.8 3.8e-10 39.3 3.3 2.1 2 0 0 2 2 2 1 Ion channel Pkinase PF00069.20 KFM09461.1 - 3.5e-63 213.1 0.3 9.3e-63 211.7 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM09461.1 - 4.5e-47 160.2 0.0 6.7e-47 159.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Mst1_SARAH PF11629.3 KFM09461.1 - 2.4e-28 97.6 2.4 5.5e-28 96.5 1.6 1.7 1 0 0 1 1 1 1 C terminal SARAH domain of Mst1 Kinase-like PF14531.1 KFM09461.1 - 0.00013 21.0 0.1 0.018 14.0 0.0 2.4 2 0 0 2 2 2 2 Kinase-like TPR_11 PF13414.1 KFM09462.1 - 6.2e-29 99.4 14.8 1.6e-14 53.3 2.2 3.2 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 KFM09462.1 - 1.2e-24 84.8 11.6 1e-09 37.5 0.3 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 KFM09462.1 - 8.4e-20 69.0 9.7 5.6e-07 28.9 0.3 4.4 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 KFM09462.1 - 2.4e-13 50.3 0.4 3.5e-07 30.7 0.1 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFM09462.1 - 4.1e-11 41.8 13.3 5.6e-05 22.6 0.1 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFM09462.1 - 5.3e-10 39.0 3.3 0.0015 19.0 0.4 4.3 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFM09462.1 - 1.2e-08 34.7 9.0 2.6e-05 24.0 0.9 3.7 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFM09462.1 - 9.1e-07 28.5 7.2 0.00034 20.5 0.1 3.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 KFM09462.1 - 2.9e-06 27.0 4.0 0.0013 18.5 0.4 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFM09462.1 - 3.2e-06 27.3 9.8 6.1e-05 23.2 3.9 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 KFM09462.1 - 9.4e-06 25.6 6.2 9.4e-06 25.6 4.3 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 KFM09462.1 - 0.00028 20.6 11.4 0.005 16.6 0.4 3.6 4 1 1 5 5 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.1 KFM09462.1 - 0.0057 16.3 6.3 1.2 9.1 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat BTAD PF03704.12 KFM09462.1 - 0.019 15.3 0.7 0.019 15.3 0.5 1.8 2 1 0 2 2 2 0 Bacterial transcriptional activator domain GNT-I PF03071.10 KFM09462.1 - 0.09 11.3 0.1 0.14 10.7 0.1 1.3 1 0 0 1 1 1 0 GNT-I family TPR_6 PF13174.1 KFM09462.1 - 0.19 12.2 12.3 0.43 11.1 0.3 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 KFM09462.1 - 1.3 8.3 5.3 4.3 6.6 0.1 3.5 4 0 0 4 4 4 0 SHNi-TPR RRM_1 PF00076.17 KFM09463.1 - 1.1e-86 284.4 1.0 9.5e-21 73.2 0.0 5.2 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM09463.1 - 4.1e-58 193.2 1.4 3.8e-13 49.2 0.0 5.1 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM09463.1 - 3.6e-42 142.0 0.1 1.3e-10 40.9 0.0 5.2 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 KFM09463.1 - 1.3e-29 101.6 0.2 3.1e-29 100.4 0.1 1.7 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 KFM09463.1 - 0.00011 21.8 0.2 4.8 7.0 0.0 4.2 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 KFM09463.1 - 0.00033 20.3 1.5 5.9 6.7 0.0 4.2 5 0 0 5 5 5 2 Limkain b1 CbiG_mid PF11761.3 KFM09463.1 - 0.036 14.3 0.1 14 6.0 0.0 3.8 4 0 0 4 4 4 0 Cobalamin biosynthesis central region OB_RNB PF08206.6 KFM09463.1 - 0.071 12.6 5.5 14 5.3 0.1 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain DUF4078 PF13300.1 KFM09463.1 - 2 8.5 7.1 24 5.1 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4078) 14-3-3 PF00244.15 KFM09464.1 - 1.5e-112 374.4 11.9 1.7e-112 374.2 8.3 1.0 1 0 0 1 1 1 1 14-3-3 protein FliM PF02154.10 KFM09464.1 - 0.042 13.5 0.2 0.072 12.7 0.1 1.3 1 0 0 1 1 1 0 Flagellar motor switch protein FliM DUF4303 PF14136.1 KFM09464.1 - 0.11 12.1 2.6 2.6 7.6 0.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4303) DUF3802 PF12290.3 KFM09464.1 - 0.22 11.8 2.3 39 4.6 0.0 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF3802) CCDC-167 PF15188.1 KFM09464.1 - 0.85 9.6 5.8 0.52 10.3 0.4 2.7 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 Drf_FH3 PF06367.11 KFM09464.1 - 1.6 8.0 5.6 0.26 10.6 0.8 2.0 3 0 0 3 3 3 0 Diaphanous FH3 Domain C2 PF00168.25 KFM09465.1 - 1.1e-12 47.6 0.0 1.6e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 C2 domain Ion_trans_2 PF07885.11 KFM09466.1 - 2e-25 88.2 13.6 1.7e-15 56.5 5.7 2.2 2 0 0 2 2 2 2 Ion channel DUF981 PF06168.6 KFM09466.1 - 0.18 11.5 4.5 0.34 10.6 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF981) Ion_trans PF00520.26 KFM09466.1 - 2.7 7.1 11.0 17 4.5 8.1 2.0 1 1 1 2 2 2 0 Ion transport protein 7tm_1 PF00001.16 KFM09467.1 - 1.1e-43 149.2 7.0 1.5e-43 148.7 4.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Cad PF03596.8 KFM09467.1 - 0.0092 15.6 0.9 0.02 14.5 0.6 1.5 1 0 0 1 1 1 1 Cadmium resistance transporter IGFBP PF00219.13 KFM09468.1 - 6.2e-13 49.0 20.7 6.2e-13 49.0 14.4 2.6 2 1 0 2 2 2 1 Insulin-like growth factor binding protein VWC PF00093.13 KFM09468.1 - 1.2e-05 25.3 3.6 1.2e-05 25.3 2.5 2.9 3 0 0 3 3 3 1 von Willebrand factor type C domain A_deaminase PF00962.17 KFM09469.1 - 7.8e-90 301.1 0.0 8.8e-90 300.9 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase PKI PF02827.11 KFM09470.1 - 3.3e-18 65.5 0.2 3.5e-18 65.5 0.1 1.0 1 0 0 1 1 1 1 cAMP-dependent protein kinase inhibitor TC1 PF15063.1 KFM09470.1 - 0.13 11.8 0.0 0.14 11.7 0.0 1.0 1 0 0 1 1 1 0 Thyroid cancer protein 1 Serinc PF03348.10 KFM09471.1 - 2e-180 600.0 19.3 2.3e-180 599.9 13.4 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) CRAL_TRIO PF00650.15 KFM09472.1 - 2.8e-33 114.6 0.0 3.9e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KFM09472.1 - 3.8e-11 42.9 0.4 1e-10 41.5 0.2 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KFM09472.1 - 8.4e-06 25.7 0.0 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Hormone_recep PF00104.25 KFM09473.1 - 1.5e-38 131.9 0.0 2.3e-38 131.3 0.0 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFM09473.1 - 3e-30 104.2 18.3 4.8e-30 103.6 12.7 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Foamy_virus_ENV PF03408.9 KFM09473.1 - 0.051 11.1 0.6 0.066 10.7 0.4 1.1 1 0 0 1 1 1 0 Foamy virus envelope protein CAP PF00188.21 KFM09475.1 - 3.7e-21 75.8 3.4 4.8e-21 75.5 2.4 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Scs3p PF10261.4 KFM09476.1 - 5.2e-34 117.3 17.5 9.8e-34 116.4 12.1 1.4 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.16 KFM09476.1 - 2.4e-05 23.9 4.2 2.4e-05 23.9 2.9 1.9 1 1 1 2 2 2 1 PAP2 superfamily ARL6IP6 PF15062.1 KFM09476.1 - 0.029 14.2 0.3 0.029 14.2 0.2 2.7 2 1 1 3 3 3 0 Haemopoietic lineage transmembrane helix GST_N_3 PF13417.1 KFM09477.1 - 4.9e-12 45.9 0.0 9.3e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFM09477.1 - 6.3e-09 35.7 0.0 1.3e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KFM09477.1 - 7.6e-07 29.2 0.0 1.6e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFM09477.1 - 5.1e-05 23.0 0.0 0.00012 21.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KFM09477.1 - 0.00056 19.8 0.1 0.0013 18.6 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF4208 PF13907.1 KFM09477.1 - 0.016 15.4 0.8 0.054 13.7 0.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4208) GST_C_3 PF14497.1 KFM09477.1 - 0.061 13.8 0.0 0.16 12.4 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF776 PF05604.6 KFM09478.1 - 9.7e-48 162.7 10.6 3.7e-47 160.8 4.4 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF776) DUF776 PF05604.6 KFM09479.1 - 6.8e-57 192.5 15.5 7e-57 192.5 8.4 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF776) MORN PF02493.15 KFM09480.1 - 1.8e-37 124.8 63.2 6.9e-07 28.6 2.2 8.5 8 0 0 8 8 8 8 MORN repeat 7tm_1 PF00001.16 KFM09481.1 - 1e-51 175.5 19.1 1.3e-51 175.2 13.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM09481.1 - 8.6e-08 31.6 18.1 3e-07 29.8 12.6 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.4 KFM09481.1 - 4.8e-05 22.6 18.5 6.3e-05 22.2 0.3 2.9 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF788 PF05620.6 KFM09481.1 - 0.66 9.8 6.4 0.52 10.1 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF788) DC_STAMP PF07782.8 KFM09482.1 - 3.5e-32 111.5 2.0 3.5e-32 111.5 1.4 1.7 2 0 0 2 2 2 1 DC-STAMP-like protein Na_sulph_symp PF00939.14 KFM09483.1 - 1.8e-105 353.5 20.3 2.2e-105 353.2 14.1 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 KFM09483.1 - 4.9e-14 51.6 28.5 1e-05 24.2 6.3 3.2 2 1 1 3 3 3 3 Citrate transporter Lipoprotein_X PF03305.8 KFM09483.1 - 0.23 10.7 1.9 0.36 10.1 1.3 1.1 1 0 0 1 1 1 0 Mycoplasma MG185/MG260 protein Kdo PF06293.9 KFM09485.1 - 1.5e-08 33.9 0.0 1.8e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KFM09485.1 - 2.7e-06 26.7 0.0 3.1e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KFM09485.1 - 4.9e-05 23.1 0.0 8.8e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KFM09485.1 - 0.0028 16.7 0.0 0.0035 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KFM09485.1 - 0.0048 16.2 0.0 0.0064 15.8 0.0 1.2 1 0 0 1 1 1 1 RIO1 family EcKinase PF02958.15 KFM09485.1 - 0.0069 15.5 0.0 0.0074 15.4 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 KFM09485.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH_6_hur PF04655.9 KFM09485.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Sugar_tr PF00083.19 KFM09486.1 - 1.1e-87 294.5 28.5 1.4e-64 218.4 9.0 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KFM09486.1 - 1.5e-29 102.8 46.5 1.1e-21 76.9 11.4 3.1 2 1 0 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.2 KFM09486.1 - 0.0025 17.5 5.2 0.67 9.7 0.2 3.1 3 0 0 3 3 3 2 MFS_1 like family MFS_3 PF05977.8 KFM09486.1 - 0.0035 15.5 14.4 0.0069 14.5 2.3 2.4 2 0 0 2 2 2 2 Transmembrane secretion effector DUF3544 PF12064.3 KFM09488.1 - 7.2e-105 349.3 20.4 7.2e-105 349.3 14.1 3.5 4 1 1 5 5 5 1 Domain of unknown function (DUF3544) Bromodomain PF00439.20 KFM09488.1 - 1.6e-15 56.7 0.0 5.5e-15 55.0 0.0 2.0 1 0 0 1 1 1 1 Bromodomain PWWP PF00855.12 KFM09488.1 - 2.6e-10 40.3 0.4 1.4e-09 38.0 0.3 2.4 1 0 0 1 1 1 1 PWWP domain PHD PF00628.24 KFM09488.1 - 9.4e-08 31.6 12.8 9.4e-08 31.6 8.9 3.7 3 0 0 3 3 3 1 PHD-finger DUF1640 PF07798.6 KFM09488.1 - 4.9e-05 23.4 6.5 6.3e-05 23.0 2.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) zf-MYND PF01753.13 KFM09488.1 - 0.00014 21.6 17.0 0.00014 21.6 11.8 4.0 3 1 0 3 3 3 1 MYND finger TRAM1 PF08390.6 KFM09489.1 - 2e-22 78.4 2.4 4.8e-22 77.2 1.6 1.7 1 0 0 1 1 1 1 TRAM1-like protein TRAM_LAG1_CLN8 PF03798.11 KFM09489.1 - 1.4e-21 77.0 13.4 2.1e-21 76.4 9.3 1.3 1 0 0 1 1 1 1 TLC domain wnt PF00110.14 KFM09490.1 - 2.2e-126 421.2 27.1 2.5e-126 421.0 18.8 1.0 1 0 0 1 1 1 1 wnt family Atx10homo_assoc PF09759.4 KFM09491.1 - 2.5e-39 133.1 7.7 4.7e-37 125.8 0.3 3.3 3 0 0 3 3 3 2 Spinocerebellar ataxia type 10 protein domain DUF484 PF04340.7 KFM09491.1 - 0.0055 16.1 0.2 0.012 15.0 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF484 HEAT_2 PF13646.1 KFM09491.1 - 0.033 14.4 0.3 0.31 11.3 0.0 2.6 3 0 0 3 3 3 0 HEAT repeats Yae1_N PF09811.4 KFM09492.1 - 2.6e-20 71.6 64.3 1.5e+04 -25.0 44.6 5.7 1 1 0 1 1 1 0 Essential protein Yae1, N terminal EGF_CA PF07645.10 KFM09493.1 - 1.1e-70 233.3 133.5 2.5e-11 43.3 3.6 10.5 10 1 0 10 10 10 9 Calcium-binding EGF domain cEGF PF12662.2 KFM09493.1 - 8.9e-57 188.2 71.8 5.2e-09 35.5 2.2 9.9 9 0 0 9 9 9 8 Complement Clr-like EGF-like FXa_inhibition PF14670.1 KFM09493.1 - 9.1e-30 102.4 131.9 7.6e-07 29.1 6.3 10.9 10 1 0 10 10 10 7 Coagulation Factor Xa inhibitory site EGF_3 PF12947.2 KFM09493.1 - 4.1e-11 42.6 118.4 0.00035 20.4 4.3 10.9 10 0 0 10 10 10 9 EGF domain ANATO PF01821.13 KFM09493.1 - 1.2e-09 38.1 20.0 6.7e-07 29.3 4.6 9.8 10 1 0 10 10 10 4 Anaphylotoxin-like domain EGF PF00008.22 KFM09493.1 - 3.4e-07 30.0 108.9 0.0028 17.5 2.7 11.6 9 1 2 11 11 11 7 EGF-like domain 7tm_1 PF00001.16 KFM09494.1 - 8.4e-39 133.2 9.6 8.4e-39 133.2 6.7 1.4 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 KFM09494.1 - 0.00013 21.2 3.3 0.00013 21.2 2.3 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.4 KFM09494.1 - 0.0016 17.6 4.2 0.003 16.7 2.9 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv YrhC PF14143.1 KFM09494.1 - 0.0039 17.0 0.1 0.031 14.2 0.0 2.6 2 1 1 3 3 3 1 YrhC-like protein TAS2R PF05296.8 KFM09494.1 - 0.046 12.6 6.5 0.48 9.2 4.5 2.0 1 1 0 1 1 1 0 Mammalian taste receptor protein (TAS2R) 7tm_1 PF00001.16 KFM09495.1 - 4.7e-31 107.8 11.5 5.5e-31 107.6 8.0 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 KFM09495.1 - 0.00023 20.4 0.8 0.00029 20.0 0.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Mfp-3 PF04202.8 KFM09496.1 - 0.97 9.6 49.6 0.65 10.2 3.1 5.7 1 1 4 5 5 5 0 Foot protein 3 E1-E2_ATPase PF00122.15 KFM09497.1 - 4.6e-61 205.7 2.6 7e-61 205.1 1.8 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KFM09497.1 - 2.8e-22 80.1 4.0 9.4e-16 58.8 0.8 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFM09497.1 - 4.4e-13 48.4 0.0 9.8e-13 47.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KFM09497.1 - 3e-12 46.3 0.0 6e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KFM09497.1 - 6e-10 39.5 0.5 8e-09 35.9 0.1 2.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFM09497.1 - 9.5e-05 22.0 4.4 0.00058 19.5 1.5 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Asp_protease PF09668.5 KFM09497.1 - 0.12 11.9 0.6 14 5.3 0.0 2.4 2 0 0 2 2 2 0 Aspartyl protease Cullin_Nedd8 PF10557.4 KFM09499.1 - 1.5e-05 24.6 0.1 0.00011 21.8 0.0 1.9 1 1 0 1 1 1 1 Cullin protein neddylation domain IBR PF01485.16 KFM09500.1 - 1.3e-10 40.9 25.9 1.3e-07 31.3 6.0 3.4 3 1 0 3 3 3 2 IBR domain LEM PF03020.10 KFM09501.1 - 1.2e-21 75.8 0.8 2.4e-21 74.8 0.5 1.5 1 0 0 1 1 1 1 LEM domain LmjF365940-deam PF14421.1 KFM09501.1 - 0.073 12.4 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases PBP1_TM PF14812.1 KFM09501.1 - 1.4 9.2 6.5 15 6.0 0.0 3.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mito_carr PF00153.22 KFM09502.1 - 7.7e-49 163.3 8.3 2.3e-20 72.0 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein PTR2 PF00854.16 KFM09502.1 - 0.022 13.5 0.1 0.028 13.1 0.1 1.2 1 0 0 1 1 1 0 POT family Sec8_exocyst PF04048.9 KFM09503.1 - 0.0038 16.8 1.1 0.0038 16.8 0.7 3.1 2 1 2 4 4 4 1 Sec8 exocyst complex component specific domain IncA PF04156.9 KFM09503.1 - 0.0056 16.3 17.1 0.048 13.2 1.3 3.0 1 1 1 2 2 2 2 IncA protein DUF4446 PF14584.1 KFM09503.1 - 0.0097 15.7 14.8 0.2 11.4 0.4 4.2 2 1 2 4 4 4 2 Protein of unknown function (DUF4446) COG5 PF10392.4 KFM09503.1 - 0.086 12.8 14.0 2.5 8.0 1.3 3.6 1 1 2 3 3 3 0 Golgi transport complex subunit 5 Reo_sigmaC PF04582.7 KFM09503.1 - 0.13 11.4 13.9 1.2 8.2 3.7 2.6 1 1 2 3 3 3 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 KFM09503.1 - 0.13 12.5 19.6 0.25 11.5 4.7 4.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein CheY-binding PF09078.6 KFM09503.1 - 0.16 11.9 1.5 1.3 9.0 0.1 2.9 3 0 0 3 3 3 0 CheY binding MHC2-interact PF09307.5 KFM09503.1 - 0.18 11.6 2.6 0.35 10.6 0.1 2.7 3 0 0 3 3 3 0 CLIP, MHC2 interacting UCH PF00443.24 KFM09503.1 - 0.18 10.9 2.4 0.48 9.4 1.7 1.7 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Snapin_Pallidin PF14712.1 KFM09503.1 - 0.62 10.4 18.5 0.21 11.9 1.0 4.6 3 3 1 4 4 4 0 Snapin/Pallidin DUF2400 PF09674.5 KFM09503.1 - 4.6 6.8 9.2 1.4 8.5 2.6 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2400) DUF148 PF02520.12 KFM09503.1 - 5.1 6.9 18.4 0.18 11.5 1.1 3.6 2 1 2 4 4 4 0 Domain of unknown function DUF148 Fib_alpha PF08702.5 KFM09503.1 - 6.6 6.8 22.3 0.16 12.0 1.3 3.6 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Gln-synt_C PF00120.19 KFM09504.1 - 8.4e-64 215.2 0.0 9.4e-64 215.0 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain GXWXG PF14231.1 KFM09504.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 GXWXG protein Arrestin_N PF00339.24 KFM09506.1 - 1.7e-19 70.0 0.0 8.5e-18 64.6 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KFM09506.1 - 1.9e-19 70.0 0.0 4.6e-18 65.6 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.2 KFM09506.1 - 0.045 13.2 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 Arrestin_N terminal like Ctr PF04145.10 KFM09508.1 - 3.8e-18 65.9 8.1 8e-18 64.8 5.6 1.5 1 1 0 1 1 1 1 Ctr copper transporter family Sec1 PF00995.18 KFM09510.1 - 1.2e-124 417.0 4.3 1.4e-124 416.8 2.9 1.0 1 0 0 1 1 1 1 Sec1 family YlbD_coat PF14071.1 KFM09510.1 - 0.0076 16.3 0.7 0.019 14.9 0.5 1.6 1 0 0 1 1 1 1 Putative coat protein Rapamycin_bind PF08771.6 KFM09510.1 - 0.017 15.2 0.5 0.99 9.5 0.2 2.5 2 0 0 2 2 2 0 Rapamycin binding domain PDZ PF00595.19 KFM09511.1 - 1.5e-24 85.9 0.4 2.7e-15 56.2 0.1 2.6 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM09511.1 - 8.2e-08 32.0 0.0 0.00013 21.8 0.0 2.7 2 1 0 2 2 2 2 PDZ domain Galanin PF01296.13 KFM09511.1 - 0.082 12.7 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 Galanin V-ATPase_G PF03179.10 KFM09512.1 - 1.1e-23 83.5 7.6 1.2e-23 83.3 5.3 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_F6 PF05511.6 KFM09512.1 - 0.0052 16.6 0.8 0.0067 16.3 0.6 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 FH2 PF02181.18 KFM09512.1 - 0.069 12.0 1.2 0.079 11.8 0.8 1.0 1 0 0 1 1 1 0 Formin Homology 2 Domain GA PF01468.12 KFM09512.1 - 0.1 12.7 1.9 0.14 12.3 0.9 1.6 1 1 0 1 1 1 0 GA module Frigida PF07899.6 KFM09512.1 - 0.2 10.3 3.1 0.23 10.1 2.2 1.2 1 0 0 1 1 1 0 Frigida-like protein RRF PF01765.14 KFM09512.1 - 1.3 8.5 5.0 1.6 8.1 3.4 1.1 1 0 0 1 1 1 0 Ribosome recycling factor Sds3 PF08598.6 KFM09512.1 - 2.1 7.8 8.6 2.1 7.7 0.3 2.0 1 1 0 2 2 2 0 Sds3-like DUF4481 PF14800.1 KFM09513.1 - 2.4e-54 184.3 5.8 2.6e-54 184.2 4.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4481) Corona_7 PF02398.11 KFM09513.1 - 0.32 11.4 2.7 0.61 10.6 1.9 1.7 1 1 0 1 1 1 0 Coronavirus protein 7 TNF PF00229.13 KFM09514.1 - 3e-35 120.5 0.1 4.2e-35 120.0 0.1 1.2 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family C1q PF00386.16 KFM09514.1 - 0.11 12.4 0.4 0.29 11.1 0.3 1.8 1 1 0 1 1 1 0 C1q domain TNF PF00229.13 KFM09515.1 - 8.2e-20 70.6 1.0 1e-19 70.3 0.1 1.5 2 0 0 2 2 2 1 TNF(Tumour Necrosis Factor) family fn3 PF00041.16 KFM09516.1 - 1.2e-136 445.1 28.9 1.4e-16 60.3 0.0 9.4 9 0 0 9 9 9 9 Fibronectin type III domain Fibrinogen_C PF00147.13 KFM09516.1 - 1.1e-82 277.1 7.1 1.7e-82 276.5 4.9 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain EGF_2 PF07974.8 KFM09516.1 - 2.9e-16 59.3 95.4 2.9e-05 24.1 9.7 5.6 5 0 0 5 5 5 4 EGF-like domain Interfer-bind PF09294.5 KFM09516.1 - 5.2e-15 55.3 0.0 0.17 11.9 0.1 7.9 8 1 1 9 9 9 4 Interferon-alpha/beta receptor, fibronectin type III hEGF PF12661.2 KFM09516.1 - 1.2e-11 43.8 43.6 0.021 14.8 1.7 6.1 5 0 0 5 5 5 5 Human growth factor-like EGF EGF PF00008.22 KFM09516.1 - 8.9e-05 22.3 77.0 0.032 14.1 7.4 5.7 5 0 0 5 5 5 3 EGF-like domain DUF2369 PF10179.4 KFM09516.1 - 0.0033 16.5 0.2 10 5.0 0.0 4.6 5 0 0 5 5 5 1 Uncharacterised conserved protein (DUF2369) Laminin_G_3 PF13385.1 KFM09517.1 - 1.6e-25 90.1 0.0 3.1e-25 89.2 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Sushi PF00084.15 KFM09517.1 - 7.8e-15 54.9 60.7 3.9e-07 30.3 3.4 8.4 8 2 0 8 8 8 4 Sushi domain (SCR repeat) Notch PF00066.12 KFM09517.1 - 2.1e-11 43.8 38.6 2.8e-07 30.6 2.1 6.4 7 0 0 7 7 7 3 LNR domain Peptidase_M43 PF05572.8 KFM09517.1 - 2.2e-08 33.8 0.1 7.6e-08 32.1 0.0 2.0 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A fn3 PF00041.16 KFM09517.1 - 0.00091 19.3 1.5 0.67 10.1 0.1 3.5 3 0 0 3 3 3 1 Fibronectin type III domain Reprolysin_3 PF13582.1 KFM09517.1 - 0.0031 18.0 0.0 0.011 16.2 0.0 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFM09517.1 - 0.0075 15.8 0.1 0.025 14.1 0.1 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFM09517.1 - 0.015 15.3 0.0 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Laminin_G_2 PF02210.19 KFM09517.1 - 0.083 12.9 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Laminin G domain Peptidase_M10 PF00413.19 KFM09517.1 - 0.66 9.6 2.2 1.4 8.6 1.5 1.5 1 1 0 1 1 1 0 Matrixin FXa_inhibition PF14670.1 KFM09518.1 - 1.3e-10 41.1 43.5 8.1e-10 38.6 2.8 4.1 4 0 0 4 4 4 3 Coagulation Factor Xa inhibitory site MACPF PF01823.14 KFM09518.1 - 1.1e-06 28.4 0.6 2.9e-06 27.1 0.2 1.8 2 0 0 2 2 2 1 MAC/Perforin domain fn3 PF00041.16 KFM09518.1 - 0.011 15.8 0.0 0.036 14.1 0.0 1.9 1 1 0 1 1 1 0 Fibronectin type III domain cEGF PF12662.2 KFM09518.1 - 4.3 7.0 10.7 0.35 10.5 0.5 3.2 3 0 0 3 3 3 0 Complement Clr-like EGF-like NHL PF01436.16 KFM09519.1 - 1.8e-29 100.1 1.4 8.5e-05 22.3 0.0 5.8 6 0 0 6 6 6 5 NHL repeat zf-RING_UBOX PF13445.1 KFM09519.1 - 1.1e-11 44.2 8.2 3.1e-11 42.8 5.7 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 KFM09519.1 - 6.1e-09 35.7 10.2 6.1e-09 35.7 7.1 3.3 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM09519.1 - 1.9e-08 33.9 8.8 1.9e-08 33.9 6.1 3.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KFM09519.1 - 5e-07 29.3 9.2 5e-07 29.3 6.4 3.4 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KFM09519.1 - 2.2e-06 27.2 10.4 2.2e-06 27.2 7.2 3.1 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.19 KFM09519.1 - 2.8e-05 23.9 3.8 2.8e-05 23.9 2.6 3.3 3 1 0 3 3 3 1 B-box zinc finger zf-C3HC4_4 PF15227.1 KFM09519.1 - 4.5e-05 23.2 9.1 4.5e-05 23.2 6.3 3.1 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.6 KFM09519.1 - 9.5e-05 22.1 0.8 9.5e-05 22.1 0.6 2.4 3 0 0 3 3 3 1 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.1 KFM09519.1 - 0.00021 20.8 5.6 0.00021 20.8 3.9 2.9 4 0 0 4 4 3 1 RING/Ubox like zinc-binding domain SGL PF08450.7 KFM09519.1 - 0.0031 16.9 0.0 10 5.4 0.0 3.8 2 1 2 4 4 4 1 SMP-30/Gluconolaconase/LRE-like region FYVE PF01363.16 KFM09519.1 - 0.0076 16.1 2.1 0.0076 16.1 1.5 3.1 3 1 0 3 3 3 2 FYVE zinc finger Glyco_transf_29 PF00777.13 KFM09520.1 - 1.2e-49 168.8 0.0 1.5e-49 168.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) LRR_8 PF13855.1 KFM09521.1 - 2.5e-54 180.8 57.5 8.2e-13 47.9 1.3 9.6 5 3 4 9 9 9 8 Leucine rich repeat TIR PF01582.15 KFM09521.1 - 1.1e-28 99.4 0.0 2.5e-28 98.3 0.0 1.6 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.2 KFM09521.1 - 2.6e-24 84.3 59.5 2.1e-06 27.1 1.3 10.9 6 4 6 13 13 13 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM09521.1 - 3.4e-15 53.7 52.0 1.2 9.4 0.2 15.9 14 2 1 15 15 15 8 Leucine Rich Repeat LRR_5 PF13306.1 KFM09521.1 - 7.5e-14 51.5 17.0 5e-07 29.4 0.1 5.0 4 1 1 5 5 5 4 Leucine rich repeats (6 copies) TIR_2 PF13676.1 KFM09521.1 - 4.3e-09 36.4 0.0 1e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 TIR domain LRR_6 PF13516.1 KFM09521.1 - 4.6e-05 23.0 59.9 0.18 11.9 0.4 14.1 14 2 2 16 16 16 4 Leucine Rich repeat LRR_9 PF14580.1 KFM09521.1 - 0.0015 18.1 16.2 0.059 12.9 0.4 4.4 3 2 1 4 4 4 2 Leucine-rich repeat Col_cuticle_N PF01484.12 KFM09521.1 - 0.036 13.7 3.6 0.65 9.7 1.7 2.6 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain LRR_7 PF13504.1 KFM09521.1 - 1.8 9.0 57.2 12 6.6 0.0 15.0 16 1 0 16 16 16 0 Leucine rich repeat MACPF PF01823.14 KFM09524.1 - 1.4e-06 28.1 1.7 1.7e-06 27.8 0.0 2.1 3 0 0 3 3 3 1 MAC/Perforin domain ATP-synt_ab PF00006.20 KFM09525.1 - 8.7e-22 77.6 0.1 1.2e-21 77.2 0.1 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KFM09525.1 - 5.4e-21 75.1 0.3 7.5e-21 74.7 0.2 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab PF00006.20 KFM09526.1 - 1e-28 100.3 0.0 1.8e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.18 KFM09526.1 - 6.3e-24 83.9 2.5 1.2e-23 83.0 1.7 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain KaiC PF06745.8 KFM09526.1 - 0.0082 15.2 0.1 0.013 14.6 0.1 1.3 1 0 0 1 1 1 1 KaiC Arch_ATPase PF01637.13 KFM09526.1 - 0.014 15.1 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase DUF258 PF03193.11 KFM09526.1 - 0.015 14.4 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 KFM09526.1 - 0.027 13.8 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KFM09526.1 - 0.051 13.8 0.1 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 ABC transporter NB-ARC PF00931.17 KFM09526.1 - 0.061 12.1 0.1 0.081 11.7 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_28 PF13521.1 KFM09526.1 - 0.098 12.6 0.1 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KFM09526.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 KFM09526.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 KFM09526.1 - 0.17 12.0 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.4 KFM09526.1 - 0.18 10.7 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CS PF04969.11 KFM09527.1 - 1.5e-09 38.2 0.3 2.1e-09 37.8 0.2 1.2 1 0 0 1 1 1 1 CS domain Pkinase_C PF00433.19 KFM09527.1 - 0.48 10.9 5.1 1.4 9.5 3.6 1.7 1 0 0 1 1 1 0 Protein kinase C terminal domain NAC PF01849.13 KFM09528.1 - 4.7e-26 90.0 1.2 1.1e-24 85.6 0.1 2.5 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 KFM09528.1 - 0.00067 19.4 0.5 0.0014 18.3 0.3 1.6 1 0 0 1 1 1 1 UBA/TS-N domain RNA_pol_Rpo13 PF12136.3 KFM09528.1 - 0.035 13.7 3.9 0.081 12.6 2.7 1.6 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain DUF2203 PF09969.4 KFM09528.1 - 4 7.6 8.2 0.9 9.7 0.6 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Casein PF00363.13 KFM09528.1 - 8 7.1 6.9 0.76 10.4 0.4 2.2 2 0 0 2 2 2 0 Casein DNA_primase_S PF01896.14 KFM09529.1 - 6.5e-32 110.3 0.2 1.7e-31 108.9 0.0 1.6 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase small subunit BTB PF00651.26 KFM09530.1 - 8.7e-24 83.6 0.1 1.7e-23 82.6 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 KFM09530.1 - 1.8e-14 53.2 51.2 8.2e-07 29.0 3.9 9.9 11 0 0 11 11 11 6 Zinc-finger double domain zf-C2H2 PF00096.21 KFM09530.1 - 1.1e-07 31.8 76.5 0.0014 18.8 2.4 9.6 10 0 0 10 10 10 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM09530.1 - 0.00013 22.0 74.9 0.063 13.6 1.7 9.8 11 0 0 11 11 11 7 C2H2-type zinc finger BolA PF01722.13 KFM09530.1 - 0.019 14.9 0.6 14 5.7 0.1 3.3 2 1 1 3 3 3 0 BolA-like protein CpXC PF14353.1 KFM09530.1 - 3.7 7.5 22.0 3.8 7.4 0.2 5.2 4 2 0 5 5 5 0 CpXC protein Myosin_head PF00063.16 KFM09531.1 - 2.4e-236 786.0 0.0 2.1e-144 482.1 0.0 2.3 2 0 0 2 2 2 2 Myosin head (motor domain) Myosin_TH1 PF06017.8 KFM09531.1 - 6.1e-33 113.8 0.0 1.2e-32 112.8 0.0 1.4 1 0 0 1 1 1 1 Myosin tail IQ PF00612.22 KFM09531.1 - 4e-09 35.3 24.9 0.0019 17.6 1.6 4.9 4 0 0 4 4 4 4 IQ calmodulin-binding motif AAA_22 PF13401.1 KFM09531.1 - 0.013 15.6 0.0 0.13 12.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KFM09531.1 - 0.034 14.9 0.0 0.11 13.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KFM09531.1 - 0.088 11.8 0.0 0.28 10.2 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 KFM09531.1 - 0.11 12.8 0.0 0.28 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF2215 PF10225.4 KFM09532.1 - 3.6e-20 72.4 0.0 4.1e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2215) DUF2215 PF10225.4 KFM09533.1 - 0.036 13.5 0.6 0.055 12.9 0.4 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) STAT_bind PF02864.10 KFM09534.1 - 1.5e-85 286.8 3.3 1.8e-85 286.5 2.3 1.1 1 0 0 1 1 1 1 STAT protein, DNA binding domain SH2 PF00017.19 KFM09534.1 - 2.1e-09 37.0 0.0 4.5e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 SH2 domain Neurexophilin PF06312.7 KFM09535.1 - 6.1e-73 244.6 1.5 6.8e-73 244.5 1.0 1.0 1 0 0 1 1 1 1 Neurexophilin CHORD PF04968.7 KFM09535.1 - 0.012 15.8 1.8 0.021 15.0 1.3 1.3 1 0 0 1 1 1 0 CHORD SHMT PF00464.14 KFM09536.1 - 4.3e-206 683.9 0.0 5e-206 683.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase C1_1 PF00130.17 KFM09537.1 - 0.0041 16.8 5.9 0.014 15.1 4.4 1.7 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.6 KFM09537.1 - 0.15 12.0 5.5 0.71 9.9 3.0 2.1 2 0 0 2 2 2 0 RING-like domain PHD_2 PF13831.1 KFM09537.1 - 0.23 10.8 3.9 0.44 9.8 2.7 1.5 1 0 0 1 1 1 0 PHD-finger R3H PF01424.17 KFM09538.1 - 2.6e-12 46.2 0.0 6.5e-12 44.9 0.0 1.8 1 0 0 1 1 1 1 R3H domain SUZ PF12752.2 KFM09538.1 - 2.7e-10 40.5 3.7 2.7e-10 40.5 2.5 4.5 5 0 0 5 5 5 1 SUZ domain TUSC2 PF15000.1 KFM09538.1 - 0.022 14.8 0.3 0.022 14.8 0.2 3.7 5 1 0 5 5 5 0 Tumour suppressor candidate 2 WD40 PF00400.27 KFM09539.1 - 1.4e-12 46.9 6.5 2.8e-07 30.1 0.2 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Cation_efflux PF01545.16 KFM09540.1 - 3.8e-42 144.3 1.2 4.5e-42 144.0 0.8 1.0 1 0 0 1 1 1 1 Cation efflux family Chromate_transp PF02417.10 KFM09540.1 - 0.072 12.6 6.0 0.2 11.2 1.0 2.2 2 0 0 2 2 2 0 Chromate transporter UPRTase PF14681.1 KFM09541.1 - 1e-75 253.4 0.2 1.5e-75 252.9 0.1 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.13 KFM09541.1 - 2.1e-28 99.2 0.4 3e-28 98.6 0.3 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Pribosyltran PF00156.22 KFM09541.1 - 0.051 13.3 0.2 0.24 11.1 0.0 2.1 2 1 0 2 2 2 0 Phosphoribosyl transferase domain Prim-Pol PF09250.6 KFM09541.1 - 0.12 12.3 0.1 0.27 11.1 0.0 1.6 2 0 0 2 2 2 0 Bifunctional DNA primase/polymerase, N-terminal DnaJ PF00226.26 KFM09542.1 - 6.1e-06 25.8 0.2 8.8e-06 25.3 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain Corona_S2 PF01601.11 KFM09542.1 - 0.5 8.3 13.0 0.58 8.1 9.0 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein zf-B_box PF00643.19 KFM09543.1 - 2.2e-05 24.2 7.7 3.9e-05 23.4 5.3 1.4 1 0 0 1 1 1 1 B-box zinc finger Prefoldin PF02996.12 KFM09543.1 - 0.02 14.5 0.0 0.55 9.9 0.0 2.3 2 0 0 2 2 2 0 Prefoldin subunit FlgN PF05130.7 KFM09543.1 - 0.022 15.0 3.1 0.032 14.4 2.1 1.2 1 0 0 1 1 1 0 FlgN protein Mpv17_PMP22 PF04117.7 KFM09544.1 - 1.1e-26 92.1 1.1 1.6e-26 91.6 0.7 1.2 1 0 0 1 1 1 1 Mpv17 / PMP22 family IF-2B PF01008.12 KFM09545.1 - 1.9e-87 292.8 0.0 3.7e-87 291.8 0.0 1.5 2 0 0 2 2 2 1 Initiation factor 2 subunit family PX PF00787.19 KFM09546.1 - 1.6e-14 53.6 0.2 4.8e-14 52.1 0.0 1.9 2 0 0 2 2 2 1 PX domain FERM_M PF00373.13 KFM09546.1 - 0.013 15.6 1.5 0.065 13.4 0.2 2.6 2 1 1 3 3 3 0 FERM central domain FERM_N PF09379.5 KFM09546.1 - 0.02 14.9 0.2 0.042 13.8 0.1 1.7 1 1 0 1 1 1 0 FERM N-terminal domain RA PF00788.18 KFM09546.1 - 0.05 14.0 0.1 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain zf-H2C2_2 PF13465.1 KFM09547.1 - 4e-42 140.4 64.5 1.7e-09 37.4 1.2 9.9 10 0 0 10 10 10 5 Zinc-finger double domain zf-H2C2_5 PF13909.1 KFM09547.1 - 6.1e-26 89.0 52.9 3.8e-05 23.6 1.2 7.3 7 0 0 7 7 7 7 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 KFM09547.1 - 1.5e-17 62.7 70.8 0.0021 18.2 0.3 8.4 9 0 0 9 9 9 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM09547.1 - 3.2e-16 58.3 67.9 0.0006 19.9 0.7 8.4 9 0 0 9 9 9 7 C2H2-type zinc finger GAGA PF09237.6 KFM09547.1 - 1.1e-05 24.8 25.1 0.049 13.2 0.3 5.5 3 2 3 6 6 6 3 GAGA factor AKAP95 PF04988.7 KFM09547.1 - 0.078 12.7 25.6 0.6 9.8 0.2 5.7 6 1 0 6 6 6 0 A-kinase anchoring protein 95 (AKAP95) DUF3505 PF12013.3 KFM09547.1 - 0.82 9.9 40.6 4.1 7.6 0.2 7.6 4 2 4 8 8 8 0 Protein of unknown function (DUF3505) Salp15 PF12115.3 KFM09547.1 - 1.6 9.0 16.0 2.1 8.5 0.2 3.4 2 1 1 3 3 3 0 Salivary protein of 15kDa inhibits CD4+ T cell activation Elf1 PF05129.8 KFM09547.1 - 2.4 7.9 27.7 2.2 8.0 1.9 5.5 3 3 2 5 5 5 0 Transcription elongation factor Elf1 like IBR PF01485.16 KFM09550.1 - 7.9e-21 73.7 37.4 1.3e-15 56.9 3.1 4.0 3 1 1 4 4 4 2 IBR domain zf-RING_5 PF14634.1 KFM09550.1 - 0.0012 18.4 5.8 0.0012 18.4 4.0 4.4 4 1 1 5 5 5 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFM09550.1 - 0.0034 17.3 8.8 0.0034 17.3 6.1 5.0 4 2 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM09550.1 - 0.0099 15.5 7.9 0.0099 15.5 5.5 4.6 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM09550.1 - 0.017 14.9 10.0 0.017 14.9 6.9 4.1 2 1 1 3 3 3 0 Ring finger domain PP2C PF00481.16 KFM09551.1 - 5e-69 232.5 1.0 2.6e-57 194.1 0.2 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 KFM09551.1 - 3.3e-05 23.3 0.3 0.0003 20.2 0.0 2.3 2 0 0 2 2 2 1 Protein phosphatase 2C Spore_coat_CotO PF14153.1 KFM09551.1 - 9.2 5.6 16.3 0.013 14.9 1.8 2.4 2 1 0 2 2 2 0 Spore coat protein CotO Pkinase PF00069.20 KFM09552.1 - 5.9e-26 91.1 0.8 1e-25 90.3 0.5 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM09552.1 - 3.7e-25 88.4 0.5 6.7e-25 87.6 0.4 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PRESAN PF09687.5 KFM09552.1 - 0.091 12.8 8.6 0.48 10.4 5.9 2.2 1 1 0 1 1 1 0 Plasmodium RESA N-terminal BCLP PF12304.3 KFM09553.1 - 2.7e-35 121.5 1.9 2.9e-35 121.3 1.3 1.0 1 0 0 1 1 1 1 Beta-casein like protein Clathrin PF00637.15 KFM09554.1 - 4.1e-10 39.4 36.6 0.046 13.3 0.2 10.0 5 3 5 11 11 11 5 Region in Clathrin and VPS WD40 PF00400.27 KFM09554.1 - 1.1e-09 37.8 7.9 0.037 13.9 0.1 7.0 6 1 0 6 6 6 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KFM09554.1 - 0.0011 17.9 0.1 0.0011 17.9 0.0 5.8 3 2 3 6 6 6 1 Coatomer WD associated region TPR_7 PF13176.1 KFM09554.1 - 0.0078 15.9 34.7 4.9 7.1 0.0 11.8 10 3 0 10 10 10 2 Tetratricopeptide repeat fn1 PF00039.13 KFM09554.1 - 0.0088 15.8 4.8 13 5.7 0.0 4.9 5 0 0 5 5 5 1 Fibronectin type I domain Mad3_BUB1_I PF08311.7 KFM09554.1 - 0.13 12.0 17.4 2.6 7.8 0.1 5.8 7 0 0 7 7 7 0 Mad3/BUB1 homology region 1 TPR_12 PF13424.1 KFM09554.1 - 0.51 10.2 49.7 0.99 9.3 0.6 12.6 11 3 1 13 13 13 0 Tetratricopeptide repeat TPR_2 PF07719.12 KFM09554.1 - 1.3 9.1 54.4 9.2 6.4 0.0 13.0 11 1 1 12 12 12 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFM09554.1 - 2.6 8.9 37.3 26 5.8 0.0 12.4 11 2 2 13 13 13 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFM09554.1 - 5.5 7.0 32.6 0.79 9.6 0.1 10.3 9 2 0 9 9 9 0 Tetratricopeptide repeat PID PF00640.18 KFM09555.1 - 2.2e-21 76.2 0.2 2.5e-21 76.1 0.1 1.0 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID_2 PF14719.1 KFM09555.1 - 2.2e-13 50.2 0.1 2.7e-13 49.9 0.1 1.0 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.8 KFM09555.1 - 2e-10 40.6 0.1 2.6e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosine-binding domain fn3 PF00041.16 KFM09556.1 - 4.1e-11 42.8 0.8 9.6e-11 41.6 0.0 1.9 2 0 0 2 2 2 1 Fibronectin type III domain DUF3357 PF11837.3 KFM09556.1 - 0.096 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) zf-C2H2_jaz PF12171.3 KFM09557.1 - 3.1e-08 33.5 14.8 0.00089 19.3 0.4 4.5 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding CpXC PF14353.1 KFM09557.1 - 1.2e-05 25.2 11.1 0.018 15.0 0.0 3.9 3 1 0 3 3 3 2 CpXC protein zf-C2H2 PF00096.21 KFM09557.1 - 1.4e-05 25.1 36.9 0.0023 18.1 2.5 6.4 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-BED PF02892.10 KFM09557.1 - 2.6e-05 23.8 32.8 0.24 11.1 4.0 5.7 4 1 1 5 5 5 4 BED zinc finger zf-C2H2_4 PF13894.1 KFM09557.1 - 3e-05 24.0 25.2 0.11 12.8 1.1 6.0 6 0 0 6 6 6 3 C2H2-type zinc finger zf-FCS PF06467.9 KFM09557.1 - 3e-05 23.5 5.4 0.022 14.3 0.2 3.5 3 0 0 3 3 3 2 MYM-type Zinc finger with FCS sequence motif zf-Di19 PF05605.7 KFM09557.1 - 0.00025 21.0 13.6 0.42 10.7 0.3 4.6 4 0 0 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 KFM09557.1 - 0.0027 17.7 21.9 0.22 11.6 0.1 4.8 3 2 1 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-ribbon_3 PF13248.1 KFM09557.1 - 0.13 11.5 13.0 0.87 8.8 1.4 3.7 3 1 0 3 3 3 0 zinc-ribbon domain IBR PF01485.16 KFM09557.1 - 0.19 11.6 26.2 0.13 12.1 0.6 4.1 3 2 0 3 3 3 0 IBR domain DZR PF12773.2 KFM09557.1 - 0.25 11.2 11.3 7.1 6.5 0.2 3.5 2 1 0 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 KFM09557.1 - 1.7 8.6 20.1 1.9 8.4 0.8 5.1 5 0 0 5 5 5 0 Zinc ribbon domain DUF629 PF04780.7 KFM09557.1 - 3.9 5.8 11.7 0.34 9.3 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF629) ATP_bind_1 PF03029.12 KFM09558.1 - 3.5e-73 246.0 0.1 5.4e-73 245.4 0.1 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 KFM09558.1 - 1.7e-06 27.6 0.1 3.4e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KFM09558.1 - 4.8e-05 22.6 0.1 9.7e-05 21.6 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B CbiA PF01656.18 KFM09558.1 - 0.0018 17.7 0.1 0.0043 16.4 0.0 1.6 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.18 KFM09558.1 - 0.0021 17.9 0.0 0.0042 17.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.14 KFM09558.1 - 0.034 13.6 0.1 0.092 12.1 0.0 1.6 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain IncA PF04156.9 KFM09558.1 - 5.2 6.6 6.7 0.49 9.9 0.2 2.0 2 0 0 2 2 2 0 IncA protein Annexin PF00191.15 KFM09559.1 - 5.3e-98 320.9 9.2 3.7e-25 87.6 0.3 4.0 4 0 0 4 4 4 4 Annexin HTH_AraC PF00165.18 KFM09559.1 - 0.099 12.5 0.5 0.35 10.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family DUF1387 PF07139.6 KFM09560.1 - 8.4e-122 406.5 12.5 1.4e-121 405.8 8.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1387) Syntaxin-6_N PF09177.6 KFM09560.1 - 0.14 12.6 1.1 0.61 10.5 0.6 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal CENP-K PF11802.3 KFM09560.1 - 0.25 10.5 4.8 0.58 9.3 3.3 1.6 1 1 0 1 1 1 0 Centromere-associated protein K TMPIT PF07851.8 KFM09560.1 - 1 8.3 3.2 1.2 8.0 0.4 1.9 1 1 1 2 2 2 0 TMPIT-like protein YbjQ_1 PF01906.12 KFM09560.1 - 1.2 9.5 3.7 14 6.1 2.6 2.1 1 1 0 1 1 1 0 Putative heavy-metal-binding ALMT PF11744.3 KFM09560.1 - 2.6 6.5 5.5 3.8 6.0 3.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Scramblase PF03803.10 KFM09561.1 - 1.8e-69 233.2 0.3 2e-69 233.0 0.2 1.0 1 0 0 1 1 1 1 Scramblase zf-C2H2 PF00096.21 KFM09562.1 - 4.2e-11 42.5 9.7 1.3e-05 25.2 0.1 4.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM09562.1 - 1.6e-10 40.7 6.9 1.3e-08 34.7 0.2 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM09562.1 - 2.1e-07 30.7 8.6 0.0014 18.8 0.1 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM09562.1 - 0.004 17.2 1.9 0.56 10.4 0.1 2.9 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 KFM09562.1 - 0.062 13.4 3.3 0.51 10.4 0.4 2.9 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding 7tm_1 PF00001.16 KFM09563.1 - 6.1e-62 209.0 24.6 7.9e-62 208.7 17.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM09563.1 - 6.5e-09 35.3 27.6 9.3e-09 34.8 19.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 60KD_IMP PF02096.15 KFM09563.1 - 0.092 12.3 6.1 0.2 11.2 4.2 1.7 1 1 0 1 1 1 0 60Kd inner membrane protein 7TM_GPCR_Srx PF10328.4 KFM09563.1 - 0.92 8.5 35.7 0.19 10.8 20.2 2.2 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Peptidase_M14 PF00246.19 KFM09564.1 - 4.8e-88 295.3 0.0 6.5e-88 294.9 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 KFM09564.1 - 5.5e-21 74.0 1.5 1.1e-20 73.1 1.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase activation peptide Glyco_transf_22 PF03901.12 KFM09566.1 - 1.1e-51 176.1 23.5 1.5e-51 175.7 16.3 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Transferrin PF00405.12 KFM09567.1 - 6.3e-226 748.4 10.4 9.4e-118 392.8 0.4 2.0 2 0 0 2 2 2 2 Transferrin Phosphonate-bd PF12974.2 KFM09567.1 - 9e-15 54.7 0.0 4.7e-06 26.1 0.0 2.5 2 1 0 2 2 2 2 ABC transporter, phosphonate, periplasmic substrate-binding protein DUF3421 PF11901.3 KFM09567.1 - 0.0081 15.8 0.0 0.22 11.2 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3421) Guanylate_kin PF00625.16 KFM09568.1 - 5.2e-65 218.3 1.7 8.4e-65 217.6 1.2 1.3 1 0 0 1 1 1 1 Guanylate kinase PDZ PF00595.19 KFM09568.1 - 1.1e-62 208.1 7.7 1.6e-20 73.0 0.1 3.5 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) PDZ_assoc PF10600.4 KFM09568.1 - 1.5e-31 108.4 5.4 3.5e-31 107.2 3.7 1.7 1 0 0 1 1 1 1 PDZ-associated domain of NMDA receptors PDZ_2 PF13180.1 KFM09568.1 - 6.2e-19 67.6 3.1 1.7e-05 24.6 0.1 4.1 4 0 0 4 4 4 3 PDZ domain MAGUK_N_PEST PF10608.4 KFM09568.1 - 8.9e-18 64.4 8.1 3.6e-11 43.3 0.7 2.9 1 1 1 2 2 2 2 Polyubiquitination (PEST) N-terminal domain of MAGUK SH3_1 PF00018.23 KFM09568.1 - 1.9e-08 33.5 0.1 5.7e-08 32.0 0.0 1.9 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFM09568.1 - 2.6e-08 33.2 0.0 6.4e-08 31.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KFM09568.1 - 0.00044 19.7 0.6 0.0023 17.4 0.0 2.5 3 0 0 3 3 3 1 Variant SH3 domain adh_short PF00106.20 KFM09569.1 - 2.3e-25 89.4 0.0 3e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFM09569.1 - 7.6e-08 32.2 0.0 1.2e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFM09569.1 - 4.7e-07 29.8 0.0 6.6e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KFM09569.1 - 1.1e-06 28.0 0.0 6.3e-06 25.5 0.0 1.8 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 KFM09569.1 - 0.021 14.5 0.1 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KFM09569.1 - 0.092 12.1 0.0 0.16 11.3 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFM09569.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding adh_short PF00106.20 KFM09570.1 - 1.6e-26 93.1 0.0 1.9e-26 92.9 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFM09570.1 - 5.9e-10 39.3 0.0 7.8e-10 38.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFM09570.1 - 1.2e-06 28.3 0.0 1.5e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFM09570.1 - 0.01 15.2 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFM09570.1 - 0.086 12.8 0.0 0.096 12.6 0.0 1.3 1 1 0 1 1 1 0 NADH(P)-binding Lipocalin_2 PF08212.7 KFM09572.1 - 3.1e-23 82.1 0.0 4.3e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.18 KFM09572.1 - 7.9e-23 81.0 0.1 9e-23 80.8 0.1 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Triabin PF03973.8 KFM09572.1 - 4.1e-05 23.2 0.2 0.00011 21.8 0.2 1.8 1 1 0 1 1 1 1 Triabin VDE PF07137.6 KFM09572.1 - 0.025 14.4 0.0 0.045 13.5 0.0 1.5 1 1 0 1 1 1 0 Violaxanthin de-epoxidase (VDE) IPP-2 PF04979.9 KFM09573.1 - 1.2e-53 180.8 12.6 1.6e-53 180.4 8.8 1.1 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) DUF3435 PF11917.3 KFM09573.1 - 0.44 9.2 4.1 0.51 8.9 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) CDC27 PF09507.5 KFM09573.1 - 0.67 9.1 16.2 0.74 8.9 11.2 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 ArfGap PF01412.13 KFM09574.1 - 2.6e-41 140.0 0.1 2.6e-41 140.0 0.1 2.6 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf Ank_2 PF12796.2 KFM09574.1 - 3.1e-20 72.2 1.0 2.2e-13 50.3 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFM09574.1 - 8.8e-14 50.5 0.6 2e-05 24.1 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat PH PF00169.24 KFM09574.1 - 2.7e-13 49.9 0.6 7e-13 48.6 0.4 1.8 1 0 0 1 1 1 1 PH domain Ank_5 PF13857.1 KFM09574.1 - 4.5e-11 42.6 0.3 4.1e-07 30.0 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFM09574.1 - 1.1e-09 38.5 0.3 0.0058 17.1 0.0 3.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM09574.1 - 1.3e-05 24.9 0.9 0.094 13.0 0.0 4.3 5 0 0 5 5 5 2 Ankyrin repeat PH_11 PF15413.1 KFM09574.1 - 3e-05 24.2 8.1 6.4e-05 23.1 1.6 3.3 2 1 0 2 2 2 1 Pleckstrin homology domain Glyco_transf_8 PF01501.15 KFM09575.1 - 7.8e-11 41.7 0.1 8.8e-11 41.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 PID_2 PF14719.1 KFM09576.1 - 9.8e-74 246.9 0.4 1.3e-73 246.5 0.3 1.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID PF00640.18 KFM09576.1 - 2.9e-05 24.0 0.0 4.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) MMR_HSR1 PF01926.18 KFM09577.1 - 9e-16 57.8 0.2 5.1e-13 48.9 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 KFM09577.1 - 3.6e-06 26.3 0.1 0.0013 18.0 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF258 PF03193.11 KFM09577.1 - 0.0007 18.8 0.0 0.0015 17.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 KFM09577.1 - 0.00082 18.5 0.0 0.0019 17.3 0.0 1.6 1 0 0 1 1 1 1 AIG1 family cobW PF02492.14 KFM09577.1 - 0.059 12.8 0.3 0.38 10.1 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 KFM09577.1 - 0.1 13.1 0.0 0.43 11.0 0.0 2.1 1 0 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 KFM09577.1 - 3.4 7.4 8.1 3.2 7.5 0.2 3.3 3 1 1 4 4 4 0 Dynamin family E1-E2_ATPase PF00122.15 KFM09578.1 - 8.6e-32 110.0 0.8 8.6e-32 110.0 0.6 2.4 3 0 0 3 3 3 1 E1-E2 ATPase HAD PF12710.2 KFM09578.1 - 9.4e-26 91.1 0.0 2.2e-25 89.9 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 KFM09578.1 - 5.8e-24 84.2 0.1 2e-23 82.5 0.1 2.0 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.21 KFM09578.1 - 1.5e-19 71.2 0.7 1.7e-11 44.9 0.1 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFM09578.1 - 1e-06 28.6 0.0 2.2e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KFM09578.1 - 1.3e-06 27.7 0.0 3.1e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF342 PF03961.8 KFM09578.1 - 0.056 11.8 0.0 0.088 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) LRR_8 PF13855.1 KFM09579.1 - 2.5e-81 267.3 58.5 8.3e-17 60.7 0.1 7.3 1 1 6 8 8 8 8 Leucine rich repeat LRR_4 PF12799.2 KFM09579.1 - 2.4e-38 129.1 43.1 1.4e-06 27.7 0.1 8.7 6 1 2 9 9 9 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFM09579.1 - 1.2e-33 115.5 0.0 3.8e-11 42.7 0.0 3.7 1 1 3 4 4 4 4 Leucine rich repeats (6 copies) LRR_1 PF00560.28 KFM09579.1 - 1e-24 82.7 38.0 0.16 12.0 0.1 13.8 14 0 0 14 14 14 8 Leucine Rich Repeat LRR_7 PF13504.1 KFM09579.1 - 9.9e-13 46.0 49.3 0.94 9.9 0.4 13.0 13 0 0 13 13 12 6 Leucine rich repeat LRR_9 PF14580.1 KFM09579.1 - 1e-11 44.6 8.9 0.01 15.3 0.3 5.3 1 1 5 6 6 6 5 Leucine-rich repeat LRR_6 PF13516.1 KFM09579.1 - 1.2e-05 24.9 26.4 2.2 8.5 0.0 10.8 13 0 0 13 13 13 1 Leucine Rich repeat LRRNT PF01462.13 KFM09579.1 - 0.0099 15.3 3.4 0.048 13.1 2.4 2.3 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain Mid2 PF04478.7 KFM09579.1 - 0.031 13.7 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Syndecan PF01034.15 KFM09579.1 - 0.11 12.1 2.6 0.32 10.6 1.8 1.7 1 0 0 1 1 1 0 Syndecan domain DUF4448 PF14610.1 KFM09579.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Dynamin_N PF00350.18 KFM09580.1 - 1.3e-36 125.9 0.1 1.3e-36 125.9 0.1 2.9 4 1 0 4 4 4 1 Dynamin family MMR_HSR1 PF01926.18 KFM09580.1 - 2.4e-05 24.2 0.0 0.00014 21.8 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFM09580.1 - 9.9e-05 21.6 0.0 0.0054 16.0 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B Miro PF08477.8 KFM09580.1 - 0.0016 18.9 0.0 0.028 14.9 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein DUF1593 PF07632.6 KFM09580.1 - 0.0048 16.2 0.0 0.016 14.5 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) GCC2_GCC3 PF07699.8 KFM09580.1 - 0.53 9.9 2.0 0.67 9.5 0.4 1.9 2 0 0 2 2 2 0 GCC2 and GCC3 AAA_28 PF13521.1 KFM09580.1 - 6.9 6.5 8.3 3.5 7.5 0.0 3.6 4 1 0 4 4 4 0 AAA domain E1-E2_ATPase PF00122.15 KFM09581.1 - 2.1e-37 128.3 0.0 4.5e-37 127.3 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase P5-ATPase PF12409.3 KFM09581.1 - 2.6e-24 85.3 0.9 5.8e-24 84.2 0.6 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter HAD PF12710.2 KFM09581.1 - 4.1e-23 82.5 0.0 7.2e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFM09581.1 - 1.2e-18 68.3 0.0 1.8e-17 64.4 0.0 2.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFM09581.1 - 4.3e-07 29.3 0.1 2.1e-06 27.0 0.0 2.3 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KFM09581.1 - 1e-05 25.4 0.0 2.3e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit DUF2620 PF10941.3 KFM09581.1 - 0.015 15.3 0.0 0.043 13.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF2620 LRAT PF04970.8 KFM09582.1 - 1.7e-39 134.6 0.0 2e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Lecithin retinol acyltransferase Peptidase_C97 PF05903.9 KFM09582.1 - 0.028 14.1 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 PPPDE putative peptidase domain NLPC_P60 PF00877.14 KFM09582.1 - 0.042 13.6 0.0 0.066 13.0 0.0 1.3 1 0 0 1 1 1 0 NlpC/P60 family Calici_PP_N PF08405.6 KFM09582.1 - 0.096 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Viral polyprotein N-terminal VWD PF00094.20 KFM09583.1 - 1.3e-99 330.8 23.2 3e-37 128.2 2.9 3.2 3 0 0 3 3 3 3 von Willebrand factor type D domain C8 PF08742.6 KFM09583.1 - 3.6e-42 142.4 9.3 8.1e-24 83.6 1.2 5.4 6 2 2 8 8 8 2 C8 domain TIL PF01826.12 KFM09583.1 - 4.8e-33 113.0 68.1 4.8e-13 49.0 11.7 7.7 6 0 0 6 6 6 3 Trypsin Inhibitor like cysteine rich domain TILa PF12714.2 KFM09583.1 - 2.7e-22 78.2 57.9 3e-09 36.5 10.5 7.2 4 2 2 6 6 6 3 TILa domain DUF4097 PF13349.1 KFM09583.1 - 1.3e-05 24.7 0.2 0.042 13.3 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4097) DUF2238 PF09997.4 KFM09583.1 - 0.015 14.6 0.4 8.7 5.7 0.0 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2238) U5_2-snRNA_bdg PF10597.4 KFM09583.1 - 0.21 11.1 0.2 7.7 6.1 0.0 2.2 2 0 0 2 2 2 0 U5-snRNA binding site 2 of PrP8 Mab-21 PF03281.9 KFM09584.1 - 8.1e-71 238.5 0.5 1.1e-70 238.0 0.3 1.2 1 0 0 1 1 1 1 Mab-21 protein FGF PF00167.13 KFM09585.1 - 3e-43 146.4 0.0 4.1e-43 146.0 0.0 1.1 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.8 KFM09585.1 - 0.015 15.3 0.0 0.035 14.1 0.0 1.6 2 0 0 2 2 2 0 Fascin domain CDtoxinA PF03498.9 KFM09585.1 - 0.035 13.4 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 Cytolethal distending toxin A/C family CCDC50_N PF15295.1 KFM09587.1 - 1.1e-53 180.7 46.3 2.8e-50 169.6 19.2 2.3 2 1 0 2 2 2 2 Coiled-coil domain-containing protein 50 N-terminus Urotensin_II PF02083.10 KFM09588.1 - 6.6e-05 22.0 4.4 0.00012 21.2 3.1 1.4 1 0 0 1 1 1 1 Urotensin II Mei5 PF10376.4 KFM09588.1 - 0.022 14.3 3.4 0.028 13.9 2.3 1.1 1 0 0 1 1 1 0 Double-strand recombination repair protein Musclin PF11037.3 KFM09589.1 - 6.6e-51 171.3 0.1 7.3e-51 171.2 0.0 1.0 1 0 0 1 1 1 1 Insulin-resistance promoting peptide in skeletal muscle RBD-FIP PF09457.5 KFM09590.1 - 0.005 16.6 4.5 0.005 16.6 3.1 1.6 2 0 0 2 2 2 1 FIP domain DUF1690 PF07956.6 KFM09590.1 - 0.46 10.4 6.2 0.84 9.6 4.3 1.3 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) TIR PF01582.15 KFM09591.1 - 2.1e-25 88.7 0.0 3.7e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 TIR domain Ig_2 PF13895.1 KFM09591.1 - 6.6e-14 51.8 0.3 0.0011 19.0 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 KFM09591.1 - 1.8e-11 44.3 1.0 0.00078 19.8 0.0 3.8 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.11 KFM09591.1 - 5.4e-10 39.0 0.1 0.00035 20.3 0.1 3.6 3 0 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.20 KFM09591.1 - 2.4e-05 24.3 4.1 0.046 13.8 0.0 4.3 4 0 0 4 4 4 2 Immunoglobulin domain TIR_2 PF13676.1 KFM09591.1 - 8.5e-05 22.6 0.0 0.0002 21.4 0.0 1.6 1 0 0 1 1 1 1 TIR domain BiPBP_C PF06832.7 KFM09591.1 - 0.0059 16.4 0.0 0.019 14.8 0.0 1.8 2 0 0 2 2 2 1 Penicillin-Binding Protein C-terminus Family TMEM52 PF14979.1 KFM09592.1 - 0.001 19.0 14.4 0.022 14.6 10.0 2.1 1 1 0 1 1 1 1 Transmembrane 52 WBP-1 PF11669.3 KFM09592.1 - 5.7 7.0 11.2 13 5.9 7.8 1.7 1 1 0 1 1 1 0 WW domain-binding protein 1 PMP22_Claudin PF00822.15 KFM09593.1 - 4.5e-19 68.7 7.9 6e-19 68.2 5.5 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFM09593.1 - 5e-11 42.5 7.3 7.7e-11 41.9 5.1 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 KFM09594.1 - 8.5e-48 162.1 10.3 9.7e-48 161.9 7.1 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFM09594.1 - 3.4e-11 43.1 9.5 4.5e-11 42.7 6.6 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction CD20 PF04103.10 KFM09594.1 - 0.009 15.9 5.8 0.013 15.3 0.5 2.4 2 1 1 3 3 3 2 CD20-like family DUF4134 PF13572.1 KFM09594.1 - 0.016 15.3 2.2 0.033 14.3 1.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4134) SUR7 PF06687.7 KFM09594.1 - 0.058 12.9 5.2 0.038 13.5 2.3 1.6 1 1 1 2 2 2 0 SUR7/PalI family DUF898 PF05987.8 KFM09594.1 - 0.094 11.5 7.6 0.15 10.9 5.3 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) Amastin PF07344.6 KFM09594.1 - 0.11 12.0 8.6 0.11 12.1 5.0 1.7 1 1 0 1 1 1 0 Amastin surface glycoprotein OppC_N PF12911.2 KFM09594.1 - 0.17 11.2 0.1 0.17 11.2 0.1 2.8 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Cytochrom_B_C PF00032.12 KFM09594.1 - 0.21 11.8 3.0 0.14 12.4 0.6 1.8 2 1 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD DUF2157 PF09925.4 KFM09594.1 - 0.26 10.8 5.8 5.4 6.6 0.0 3.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2157) IncA PF04156.9 KFM09594.1 - 0.32 10.5 5.4 1.4 8.4 0.0 3.1 3 0 0 3 3 3 0 IncA protein DUF981 PF06168.6 KFM09594.1 - 0.63 9.7 6.2 5.5 6.7 4.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF981) HlyIII PF03006.15 KFM09594.1 - 0.87 8.9 4.8 2 7.7 3.3 1.8 1 1 0 1 1 1 0 Haemolysin-III related DUF872 PF05915.7 KFM09594.1 - 1.9 8.3 6.5 1.4 8.7 1.7 2.1 1 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF4282 PF14110.1 KFM09594.1 - 2.4 8.4 11.0 0.16 12.1 1.4 2.4 3 0 0 3 3 2 0 Domain of unknown function (DUF4282) DUF1282 PF06930.7 KFM09594.1 - 3.7 7.1 9.1 8.7 5.9 6.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) Tetraspannin PF00335.15 KFM09594.1 - 5.2 6.2 16.1 1.3 8.2 2.9 2.6 1 1 1 2 2 2 0 Tetraspanin family DUF4064 PF13273.1 KFM09594.1 - 8.2 6.5 13.0 3.7 7.7 0.7 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF4131 PF13567.1 KFM09594.1 - 9.1 5.6 7.3 1.1 8.5 0.1 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) 2OG-FeII_Oxy_3 PF13640.1 KFM09595.1 - 6.2e-15 55.5 0.0 4.1e-14 52.8 0.0 2.4 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KFM09595.1 - 4.1e-05 23.1 0.1 0.00018 21.0 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KFM09595.1 - 5e-05 23.5 0.0 0.00015 22.0 0.0 1.9 2 0 0 2 2 1 1 2OG-Fe(II) oxygenase superfamily TPR_14 PF13428.1 KFM09595.1 - 0.0021 18.5 0.6 0.35 11.6 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KFM09595.1 - 0.0023 17.7 1.3 0.0091 15.8 0.1 2.3 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.1 KFM09595.1 - 0.0065 16.1 2.6 3.6 7.6 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFM09595.1 - 0.0066 16.2 7.0 1 9.4 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat Oxygenase-NA PF09859.4 KFM09595.1 - 0.011 15.1 0.0 0.23 10.7 0.0 2.3 1 1 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA YfiO PF13525.1 KFM09595.1 - 0.016 14.7 5.3 0.52 9.7 0.1 3.1 3 0 0 3 3 3 0 Outer membrane lipoprotein TPR_9 PF13371.1 KFM09595.1 - 0.018 14.8 0.4 0.33 10.8 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFM09595.1 - 0.026 14.1 7.3 0.94 9.2 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 KFM09595.1 - 0.028 14.0 7.3 0.21 11.2 0.1 2.9 3 0 0 3 3 3 0 TPR repeat TPR_12 PF13424.1 KFM09595.1 - 0.05 13.5 2.0 2.1 8.3 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat P53 PF00870.13 KFM09596.1 - 5e-108 359.0 2.2 1.5e-107 357.5 0.5 2.1 2 0 0 2 2 2 1 P53 DNA-binding domain P53_tetramer PF07710.6 KFM09596.1 - 3.4e-18 64.4 0.3 6.2e-18 63.6 0.2 1.5 1 0 0 1 1 1 1 P53 tetramerisation motif SAM_2 PF07647.12 KFM09596.1 - 7.5e-10 38.5 0.0 1.4e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) LIM PF00412.17 KFM09597.1 - 1.4e-36 124.3 28.5 4.9e-14 52.1 5.0 3.1 3 0 0 3 3 3 3 LIM domain Mut7-C PF01927.11 KFM09597.1 - 8.8 6.2 17.2 0.18 11.7 0.5 3.2 2 1 0 2 2 2 0 Mut7-C RNAse domain BTB PF00651.26 KFM09598.1 - 5.8e-27 93.8 0.3 9.8e-27 93.1 0.2 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 KFM09598.1 - 1.4e-25 88.2 54.4 1.4e-07 31.4 0.4 7.0 8 0 0 8 8 8 5 Zinc-finger double domain zf-C2H2 PF00096.21 KFM09598.1 - 1.1e-17 63.2 57.8 4.1e-05 23.6 0.2 7.5 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-met PF12874.2 KFM09598.1 - 2.5e-11 43.3 32.2 0.0076 16.4 0.1 7.1 6 0 0 6 6 6 5 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 KFM09598.1 - 7.2e-11 41.6 59.9 0.011 15.9 0.4 8.0 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM09598.1 - 1e-09 38.2 20.1 0.047 13.8 1.4 6.4 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFM09598.1 - 0.0074 16.1 34.9 0.056 13.3 0.2 6.9 7 0 0 7 7 7 4 C2H2-type zinc finger DUF3342 PF11822.3 KFM09598.1 - 0.0076 15.4 0.4 0.0076 15.4 0.3 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF3342) zf-H2C2_5 PF13909.1 KFM09598.1 - 0.18 12.1 0.1 0.18 12.1 0.1 6.5 7 1 0 7 7 7 0 C2H2-type zinc-finger domain GAGA PF09237.6 KFM09598.1 - 1 8.9 17.2 5.9 6.5 0.0 5.1 1 1 4 5 5 5 0 GAGA factor Somatostatin PF03002.10 KFM09599.1 - 2.2e-12 46.2 8.1 3.1e-12 45.7 5.6 1.2 1 0 0 1 1 1 1 Somatostatin/Cortistatin family Trypsin PF00089.21 KFM09600.1 - 4.1e-56 190.0 0.0 5.9e-56 189.5 0.0 1.2 1 0 0 1 1 1 1 Trypsin CUB PF00431.15 KFM09600.1 - 1.3e-48 163.6 0.7 4.3e-28 97.5 0.1 2.5 2 0 0 2 2 2 2 CUB domain Sushi PF00084.15 KFM09600.1 - 6.6e-13 48.8 17.2 1.6e-07 31.5 0.3 4.3 4 0 0 4 4 4 2 Sushi domain (SCR repeat) FXa_inhibition PF14670.1 KFM09600.1 - 8.4e-09 35.4 11.0 8.4e-08 32.2 5.8 3.0 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site CUB_2 PF02408.15 KFM09600.1 - 5.8e-06 25.8 0.1 0.014 14.8 0.0 2.9 3 0 0 3 3 3 2 CUB-like domain EGF_CA PF07645.10 KFM09600.1 - 2.3e-05 24.2 7.9 2.3e-05 24.2 5.5 2.6 3 0 0 3 3 3 1 Calcium-binding EGF domain Trypsin_2 PF13365.1 KFM09600.1 - 8.3e-05 22.5 0.0 0.00017 21.5 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain cEGF PF12662.2 KFM09600.1 - 0.0041 16.7 3.6 0.0041 16.7 2.5 3.1 3 0 0 3 3 3 1 Complement Clr-like EGF-like V-set PF07686.12 KFM09601.1 - 5.3e-11 42.4 0.0 9.2e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 KFM09601.1 - 0.0002 21.3 0.0 0.00048 20.1 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFM09601.1 - 0.00076 19.5 2.7 0.0042 17.1 0.5 2.7 2 1 0 2 2 2 1 Immunoglobulin domain I-set PF07679.11 KFM09601.1 - 0.0021 17.8 0.0 0.0067 16.2 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin I-set domain Tctex-1 PF03645.8 KFM09602.1 - 1.3e-13 50.6 0.1 1.4e-13 50.4 0.1 1.0 1 0 0 1 1 1 1 Tctex-1 family RasGAP PF00616.14 KFM09602.1 - 0.12 12.0 0.0 0.12 11.9 0.0 1.0 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase CTP_transf_2 PF01467.21 KFM09603.1 - 5.7e-23 81.6 0.5 9.2e-23 81.0 0.0 1.6 2 0 0 2 2 2 1 Cytidylyltransferase GldM_N PF12081.3 KFM09603.1 - 0.025 14.1 0.4 0.04 13.4 0.3 1.3 1 0 0 1 1 1 0 GldM N-terminal domain Lipoprotein_6 PF01441.14 KFM09603.1 - 0.1 12.3 3.2 0.18 11.6 2.2 1.3 1 0 0 1 1 1 0 Lipoprotein KH_5 PF13184.1 KFM09603.1 - 0.33 10.7 3.2 0.44 10.3 1.3 1.8 2 0 0 2 2 2 0 NusA-like KH domain Solute_trans_a PF03619.11 KFM09604.1 - 5.2e-18 65.3 6.3 6.4e-18 65.0 4.4 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha TFR_dimer PF04253.10 KFM09605.1 - 1.9e-26 92.0 0.0 3.9e-26 91.0 0.0 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 KFM09605.1 - 1.3e-11 44.5 0.0 4.8e-11 42.7 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.17 KFM09605.1 - 1.1e-05 25.0 0.1 2.4e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 PA domain NIDO PF06119.9 KFM09606.1 - 1.2e-09 38.6 0.1 2.1e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Nidogen-like AMOP PF03782.12 KFM09607.1 - 0.058 13.3 0.5 2 8.4 0.3 2.0 1 1 0 1 1 1 0 AMOP domain NIDO PF06119.9 KFM09609.1 - 3.6e-09 37.2 0.9 4.7e-09 36.8 0.2 1.5 2 0 0 2 2 2 1 Nidogen-like FAD_binding_7 PF03441.9 KFM09610.1 - 2.6e-36 125.2 2.3 2.6e-36 125.2 1.6 1.8 2 1 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 KFM09610.1 - 1e-21 77.4 0.0 2.4e-21 76.2 0.0 1.6 2 0 0 2 2 2 1 DNA photolyase DUF4206 PF13901.1 KFM09611.1 - 5.6e-73 244.8 14.0 5.6e-73 244.8 9.7 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4206) RUN PF02759.14 KFM09611.1 - 1.8e-09 37.4 0.1 4.3e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 RUN domain FYTT PF07078.6 KFM09612.1 - 8.2e-118 393.3 16.9 9.7e-118 393.0 11.7 1.1 1 0 0 1 1 1 1 Forty-two-three protein LRR_4 PF12799.2 KFM09613.1 - 1.7e-25 88.1 17.8 1.4e-07 30.9 0.7 5.7 5 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM09613.1 - 5.6e-23 80.4 14.3 1.1e-09 37.8 0.6 3.5 2 1 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 KFM09613.1 - 1.3e-17 61.0 24.3 0.044 13.8 0.0 9.3 8 1 0 8 8 8 6 Leucine Rich Repeat CH PF00307.26 KFM09613.1 - 2e-10 40.6 0.0 4.4e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain LRR_7 PF13504.1 KFM09613.1 - 1.1e-09 36.8 19.4 0.25 11.6 0.2 8.7 8 0 0 8 8 8 3 Leucine rich repeat LRR_6 PF13516.1 KFM09613.1 - 1.1e-05 24.9 14.7 1.1 9.4 0.4 7.7 9 0 0 9 9 9 2 Leucine Rich repeat CAMSAP_CH PF11971.3 KFM09613.1 - 0.00042 19.9 0.1 0.0014 18.1 0.0 1.9 2 0 0 2 2 2 1 CAMSAP CH domain IQ PF00612.22 KFM09614.1 - 8.5e-05 21.8 0.1 0.00021 20.6 0.1 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif Ribosomal_L35Ae PF01247.13 KFM09615.1 - 7.9e-43 144.1 0.9 8.9e-43 143.9 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 KFM09615.1 - 0.077 12.9 0.0 1.4 8.8 0.0 2.1 2 0 0 2 2 2 0 RimM N-terminal domain DUF4630 PF15443.1 KFM09616.1 - 1.2e-05 25.1 0.0 1.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4630) PC_rep PF01851.17 KFM09617.1 - 2.4e-48 159.7 15.9 8.8e-09 35.1 0.0 9.0 8 0 0 8 8 8 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KFM09617.1 - 2e-20 72.8 0.6 7.6e-13 48.5 0.0 5.4 3 1 2 5 5 5 3 HEAT repeats HEAT PF02985.17 KFM09617.1 - 2.3e-08 33.4 0.3 0.63 10.2 0.0 5.6 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 KFM09617.1 - 2.2e-07 31.1 0.1 0.011 16.1 0.0 4.6 4 1 0 4 4 4 2 HEAT-like repeat HEAT_PBS PF03130.11 KFM09617.1 - 0.0015 18.8 1.6 5.5 7.7 0.0 4.6 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Tim54 PF11711.3 KFM09617.1 - 0.15 10.6 7.0 0.24 9.9 4.9 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Tom37_C PF11801.3 KFM09617.1 - 0.15 11.8 4.6 0.33 10.8 3.2 1.5 1 0 0 1 1 1 0 Tom37 C-terminal domain PcfK PF14058.1 KFM09617.1 - 2.7 8.1 15.2 6.1 6.9 10.5 1.6 1 0 0 1 1 1 0 PcfK-like protein NARP1 PF12569.3 KFM09617.1 - 3.4 6.3 11.1 7.1 5.2 7.7 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 7tm_1 PF00001.16 KFM09618.1 - 8e-69 231.6 14.0 1.1e-68 231.1 9.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM09618.1 - 9.7e-12 44.5 15.3 3.2e-11 42.9 10.6 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM09618.1 - 6.2e-05 22.2 8.7 6.2e-05 22.2 6.0 2.5 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF3930 PF13067.1 KFM09618.1 - 2.8 7.8 6.0 0.3 10.9 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3930) FOP_dimer PF09398.5 KFM09619.1 - 0.0097 15.8 0.0 0.11 12.4 0.0 2.7 2 0 0 2 2 2 1 FOP N terminal dimerisation domain CENP-B_dimeris PF09026.5 KFM09619.1 - 0.011 15.9 4.1 0.011 15.9 2.8 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain HEAT_2 PF13646.1 KFM09619.1 - 0.021 15.0 0.2 0.12 12.6 0.1 2.4 2 1 1 3 3 3 0 HEAT repeats DUF1251 PF06856.6 KFM09619.1 - 0.093 12.2 0.0 0.63 9.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1251) RRM_1 PF00076.17 KFM09620.1 - 1.8e-68 226.0 7.4 1.9e-17 62.6 0.1 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM09620.1 - 2.5e-51 171.5 0.6 7.7e-14 51.4 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM09620.1 - 2.8e-28 97.5 0.1 5e-07 29.4 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KFM09620.1 - 0.00028 20.5 4.1 0.63 9.8 0.0 4.6 3 1 1 4 4 4 1 Limkain b1 DUF4283 PF14111.1 KFM09620.1 - 0.004 16.2 0.1 3.4 6.7 0.0 3.2 2 1 1 3 3 3 2 Domain of unknown function (DUF4283) Toxin_10 PF05431.6 KFM09620.1 - 0.014 15.0 1.6 3.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Insecticidal Crystal Toxin, P42 DbpA PF03880.10 KFM09620.1 - 0.024 14.2 0.2 1.1 9.0 0.0 3.4 4 0 0 4 4 4 0 DbpA RNA binding domain Nup35_RRM_2 PF14605.1 KFM09620.1 - 0.054 13.2 0.0 5.9 6.7 0.0 3.3 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Nucleoplasmin PF03066.10 KFM09620.1 - 3.7 7.0 74.8 0.64 9.5 7.2 3.8 4 0 0 4 4 4 0 Nucleoplasmin GMP_PDE_delta PF05351.6 KFM09621.1 - 3.2e-44 150.4 0.0 3.9e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 GMP-PDE, delta subunit PQQ PF01011.16 KFM09621.1 - 0.065 12.7 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat PCI PF01399.22 KFM09622.1 - 2.7e-12 46.9 2.3 1.4e-11 44.6 0.1 2.3 2 0 0 2 2 2 1 PCI domain ATPase-cat_bd PF12156.3 KFM09622.1 - 0.068 13.7 0.4 0.14 12.6 0.3 1.5 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase Band_3_cyto PF07565.8 KFM09622.1 - 0.26 10.7 7.1 0.66 9.4 4.9 1.6 1 1 0 1 1 1 0 Band 3 cytoplasmic domain RNB PF00773.14 KFM09623.1 - 1.6e-96 323.4 0.0 2.1e-96 323.0 0.0 1.2 1 0 0 1 1 1 1 RNB domain OB_RNB PF08206.6 KFM09623.1 - 0.1 12.0 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease B OB domain Alk_phosphatase PF00245.15 KFM09624.1 - 1e-156 521.8 0.1 1.2e-156 521.7 0.1 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 KFM09624.1 - 0.0026 17.1 0.0 0.0044 16.4 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Alk_phosphatase PF00245.15 KFM09625.1 - 5.2e-162 539.3 0.0 6e-162 539.1 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 KFM09625.1 - 0.011 15.1 0.2 0.022 14.1 0.2 1.4 1 0 0 1 1 1 0 Metalloenzyme superfamily Peptidase_M13_N PF05649.8 KFM09626.1 - 5.3e-101 338.4 0.0 6.8e-101 338.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 KFM09626.1 - 2e-62 210.0 0.1 3.1e-62 209.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M13 AA_permease PF00324.16 KFM09627.1 - 4.9e-21 74.6 6.3 6e-21 74.3 4.3 1.1 1 0 0 1 1 1 1 Amino acid permease Trypsin PF00089.21 KFM09628.1 - 3.8e-43 147.6 0.0 4.2e-43 147.4 0.0 1.0 1 0 0 1 1 1 1 Trypsin Neur_chan_LBD PF02931.18 KFM09629.1 - 1.4e-73 246.6 4.7 2e-73 246.1 3.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFM09629.1 - 1.3e-63 215.0 0.1 1.8e-63 214.6 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF4577 PF15145.1 KFM09629.1 - 0.91 9.4 3.5 0.81 9.5 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4577) IF4E PF01652.13 KFM09630.1 - 1.2e-61 206.9 0.1 1.6e-61 206.6 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E p450 PF00067.17 KFM09631.1 - 1.6e-121 406.0 0.0 1.9e-121 405.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KFM09632.1 - 5.7e-119 397.6 0.0 6.5e-119 397.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KFM09633.1 - 4.7e-123 411.1 0.2 5.3e-123 410.9 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KFM09634.1 - 4.1e-121 404.7 0.0 4.6e-121 404.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KFM09635.1 - 4.4e-124 414.5 0.1 5e-124 414.3 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_C2 PF00648.16 KFM09636.1 - 6.3e-76 255.2 0.2 9.2e-76 254.6 0.1 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 KFM09636.1 - 1.2e-61 206.7 0.0 6.2e-32 110.2 0.0 2.3 2 0 0 2 2 2 2 Calpain large subunit, domain III Peptidase_M1 PF01433.15 KFM09637.1 - 1.8e-51 175.4 0.0 2.3e-51 175.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 KFM09637.1 - 1.2e-39 135.1 0.1 2.7e-39 134.0 0.1 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 KFM09637.1 - 8.6e-16 58.1 0.0 2.2e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 Peptidase MA superfamily DUF2268 PF10026.4 KFM09637.1 - 0.0058 16.0 0.0 0.0095 15.3 0.0 1.4 1 0 0 1 1 1 1 Predicted Zn-dependent protease (DUF2268) DUF1570 PF07607.6 KFM09637.1 - 0.022 14.7 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1570) ABC_tran PF00005.22 KFM09638.1 - 4e-53 179.4 0.0 7.1e-31 107.3 0.0 3.0 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KFM09638.1 - 1.2e-44 152.7 32.7 1.4e-27 96.7 6.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 KFM09638.1 - 6.9e-12 45.0 4.8 0.011 14.9 0.0 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KFM09638.1 - 8.9e-11 42.2 4.8 0.032 14.1 0.0 4.5 2 2 1 4 4 4 4 AAA domain AAA_29 PF13555.1 KFM09638.1 - 0.00028 20.3 1.5 0.66 9.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.7 KFM09638.1 - 0.00045 19.3 1.3 0.11 11.6 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin MMR_HSR1 PF01926.18 KFM09638.1 - 0.00095 19.1 1.2 1 9.3 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 KFM09638.1 - 0.0013 18.5 1.8 0.036 13.8 0.0 3.2 3 0 0 3 3 3 1 Dynamin family AAA_23 PF13476.1 KFM09638.1 - 0.0016 18.7 6.6 0.061 13.6 0.1 3.4 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 KFM09638.1 - 0.0024 18.6 0.0 1.9 9.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KFM09638.1 - 0.0054 17.2 7.6 0.2 12.1 0.2 3.5 3 0 0 3 3 3 1 Miro-like protein AAA_18 PF13238.1 KFM09638.1 - 0.0076 16.5 0.1 1.3 9.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KFM09638.1 - 0.0095 15.1 1.3 0.45 9.6 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 T2SE PF00437.15 KFM09638.1 - 0.022 13.6 0.0 5.8 5.7 0.0 2.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_25 PF13481.1 KFM09638.1 - 0.025 13.9 0.1 6.7 6.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KFM09638.1 - 0.036 14.0 0.0 12 5.8 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain cobW PF02492.14 KFM09638.1 - 0.057 12.8 2.1 0.096 12.1 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain LVIVD PF08309.6 KFM09638.1 - 0.099 11.6 0.1 0.23 10.4 0.1 1.6 1 0 0 1 1 1 0 LVIVD repeat FtsK_SpoIIIE PF01580.13 KFM09638.1 - 0.17 11.3 0.7 3.5 7.0 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.12 KFM09638.1 - 0.29 10.9 4.7 1.3 8.7 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function DUF87 MobB PF03205.9 KFM09638.1 - 0.3 10.7 5.2 1.8 8.2 0.2 2.8 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 KFM09638.1 - 4.5 7.4 12.2 33 4.6 0.6 4.3 2 2 1 3 3 3 0 AAA domain W2 PF02020.13 KFM09639.1 - 1.7e-19 69.5 2.1 1.7e-19 69.5 1.5 2.8 3 1 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 KFM09639.1 - 2.3e-12 45.8 8.5 0.00027 20.3 3.4 4.3 2 1 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KFM09639.1 - 0.036 13.6 10.1 0.88 9.1 0.1 3.8 2 1 2 4 4 4 0 Hexapeptide repeat of succinyl-transferase Dsh_C PF12316.3 KFM09640.1 - 6.4e-83 277.8 34.1 6.4e-83 277.8 23.6 3.0 2 1 1 3 3 3 1 Segment polarity protein dishevelled (Dsh) C terminal Dishevelled PF02377.10 KFM09640.1 - 1e-31 108.9 10.1 1e-31 108.9 7.0 3.4 4 1 0 4 4 4 1 Dishevelled specific domain PDZ PF00595.19 KFM09640.1 - 1.5e-20 73.1 0.3 2.5e-20 72.4 0.2 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) DEP PF00610.16 KFM09640.1 - 1.2e-17 63.4 0.1 3e-17 62.1 0.0 1.8 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DIX PF00778.12 KFM09640.1 - 2.3e-07 30.4 0.0 4.8e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 DIX domain PDZ_2 PF13180.1 KFM09640.1 - 0.0016 18.2 0.1 0.0028 17.5 0.1 1.4 1 0 0 1 1 1 1 PDZ domain Shufflon_N PF04917.7 KFM09640.1 - 0.026 13.6 0.1 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial shufflon protein, N-terminal constant region NST1 PF13945.1 KFM09640.1 - 6.9 6.6 13.1 13 5.8 4.8 2.5 3 0 0 3 3 3 0 Salt tolerance down-regulator SAGA-Tad1 PF12767.2 KFM09640.1 - 9.9 5.7 12.1 0.57 9.7 0.1 2.5 3 0 0 3 3 3 0 Transcriptional regulator of RNA polII, SAGA, subunit Adap_comp_sub PF00928.16 KFM09641.1 - 1.3e-84 283.4 0.1 1.6e-84 283.0 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KFM09641.1 - 5.9e-06 26.0 0.5 9.9e-06 25.3 0.3 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 KFM09641.1 - 0.043 12.9 0.0 0.079 12.1 0.0 1.4 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain ALG3 PF05208.8 KFM09642.1 - 1.1e-143 479.0 12.3 1.3e-143 478.7 8.6 1.0 1 0 0 1 1 1 1 ALG3 protein EpsG PF14897.1 KFM09642.1 - 5.5e-06 25.5 9.3 8.9e-06 24.8 6.4 1.3 1 0 0 1 1 1 1 EpsG family HCaRG PF07258.9 KFM09643.1 - 5e-28 97.8 0.5 5.5e-28 97.7 0.3 1.0 1 0 0 1 1 1 1 HCaRG protein HbrB PF08539.6 KFM09645.1 - 5.9e-30 104.2 0.7 3.5e-28 98.4 0.5 2.3 1 1 0 1 1 1 1 HbrB-like zf-TRAF PF02176.13 KFM09646.1 - 8.8e-28 96.4 27.8 2.3e-18 66.3 2.3 4.0 2 1 1 3 3 3 3 TRAF-type zinc finger MATH PF00917.21 KFM09646.1 - 2e-24 86.1 0.0 4.4e-24 85.0 0.0 1.6 1 0 0 1 1 1 1 MATH domain zf-C3HC4_2 PF13923.1 KFM09646.1 - 2.6e-10 40.1 5.5 2.6e-10 40.1 3.8 3.8 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM09646.1 - 7.3e-09 35.3 4.3 7.3e-09 35.3 3.0 3.8 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.20 KFM09646.1 - 1.2e-08 34.4 4.5 1.2e-08 34.4 3.1 4.1 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM09646.1 - 1.8e-06 27.5 4.4 1.8e-06 27.5 3.1 4.0 2 1 2 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFM09646.1 - 2e-06 27.5 4.3 2e-06 27.5 3.0 3.9 2 1 2 4 4 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KFM09646.1 - 4.3e-05 23.1 4.2 4.3e-05 23.1 2.9 4.1 2 1 1 3 3 2 1 zinc-RING finger domain PspA_IM30 PF04012.7 KFM09646.1 - 0.00026 20.4 1.2 0.0007 19.0 0.8 1.7 1 0 0 1 1 1 1 PspA/IM30 family SlyX PF04102.7 KFM09646.1 - 0.00068 19.9 2.8 0.00068 19.9 1.9 2.1 2 0 0 2 2 2 1 SlyX Spc7 PF08317.6 KFM09646.1 - 0.0022 16.6 0.1 0.0037 15.9 0.1 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Med21 PF11221.3 KFM09646.1 - 0.0036 17.2 0.0 0.0065 16.4 0.0 1.5 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Sina PF03145.11 KFM09646.1 - 0.0072 15.9 20.9 0.047 13.3 4.3 3.4 1 1 2 3 3 3 2 Seven in absentia protein family zf-RING_UBOX PF13445.1 KFM09646.1 - 0.012 15.2 6.1 0.012 15.2 4.2 2.3 2 0 0 2 2 1 0 RING-type zinc-finger CENP-F_leu_zip PF10473.4 KFM09646.1 - 0.014 15.2 1.9 0.043 13.6 1.3 1.8 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4455 PF14643.1 KFM09646.1 - 0.016 13.8 0.6 0.024 13.2 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) Tropomyosin_1 PF12718.2 KFM09646.1 - 0.018 14.8 1.4 0.035 13.9 0.9 1.3 1 0 0 1 1 1 0 Tropomyosin like Myosin_tail_1 PF01576.14 KFM09646.1 - 0.022 12.4 1.5 0.033 11.9 1.0 1.2 1 0 0 1 1 1 0 Myosin tail CENP-Q PF13094.1 KFM09646.1 - 0.033 14.2 0.2 0.074 13.0 0.2 1.5 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit ATG16 PF08614.6 KFM09646.1 - 0.038 13.8 0.3 0.067 13.0 0.2 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.3 KFM09646.1 - 0.039 13.7 2.5 0.075 12.8 1.8 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Tropomyosin PF00261.15 KFM09646.1 - 0.045 12.8 1.2 0.072 12.1 0.8 1.2 1 0 0 1 1 1 0 Tropomyosin U-box PF04564.10 KFM09646.1 - 0.045 13.7 0.1 0.2 11.6 0.0 2.1 2 0 0 2 2 1 0 U-box domain Synaphin PF05835.7 KFM09646.1 - 0.059 13.5 0.5 0.12 12.4 0.4 1.5 1 0 0 1 1 1 0 Synaphin protein TSC22 PF01166.13 KFM09646.1 - 0.061 13.3 1.3 6.9 6.7 0.0 3.2 1 1 2 3 3 3 0 TSC-22/dip/bun family AAA_13 PF13166.1 KFM09646.1 - 0.068 11.6 0.6 0.1 11.0 0.4 1.2 1 0 0 1 1 1 0 AAA domain Cortex-I_coil PF09304.5 KFM09646.1 - 0.11 12.5 3.4 0.13 12.3 0.9 2.1 2 0 0 2 2 2 0 Cortexillin I, coiled coil DM PF00751.13 KFM09646.1 - 0.23 11.0 17.3 0.38 10.3 2.6 3.6 1 1 2 3 3 3 0 DM DNA binding domain DUF1664 PF07889.7 KFM09646.1 - 0.28 10.9 1.3 0.72 9.6 0.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) RAG1 PF12940.2 KFM09647.1 - 5.5e-236 782.9 0.1 8.5e-236 782.3 0.1 1.3 1 0 0 1 1 1 1 Recombination-activation protein 1 (RAG1) zf-RAG1 PF10426.4 KFM09647.1 - 1.5e-16 59.9 2.2 1.5e-16 59.9 1.5 3.6 3 0 0 3 3 3 1 Recombination-activating protein 1 zinc-finger domain zf-C3HC4 PF00097.20 KFM09647.1 - 6.2e-07 28.9 14.6 6.2e-07 28.9 10.1 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM09647.1 - 8.5e-06 25.7 15.4 8.5e-06 25.7 10.7 4.1 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KFM09647.1 - 0.00038 20.1 10.5 0.00038 20.1 7.3 3.0 2 1 1 3 3 3 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 KFM09647.1 - 0.01 15.6 14.0 0.01 15.6 9.7 3.1 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KFM09647.1 - 0.052 13.2 9.2 0.18 11.5 6.4 2.0 1 0 0 1 1 1 0 RING-type zinc-finger RAG2 PF03089.9 KFM09648.1 - 5.3e-179 594.1 0.1 6.8e-179 593.8 0.0 1.1 1 0 0 1 1 1 1 Recombination activating protein 2 RAG2_PHD PF13341.1 KFM09648.1 - 1.6e-45 152.9 2.1 3.4e-45 151.8 1.4 1.6 1 0 0 1 1 1 1 RAG2 PHD domain Kelch_3 PF13415.1 KFM09648.1 - 7e-09 35.6 0.0 0.00041 20.4 0.0 4.1 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.1 KFM09648.1 - 1e-06 28.5 0.5 0.24 11.3 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 KFM09648.1 - 0.00022 20.9 0.6 17 5.2 0.0 4.8 5 0 0 5 5 5 1 Galactose oxidase, central domain PHD PF00628.24 KFM09648.1 - 0.0023 17.6 1.4 0.0054 16.3 0.1 2.3 2 0 0 2 2 2 1 PHD-finger Kelch_1 PF01344.20 KFM09648.1 - 0.01 15.3 0.2 0.68 9.5 0.0 3.3 4 0 0 4 4 4 0 Kelch motif Kelch_6 PF13964.1 KFM09648.1 - 0.057 13.6 3.2 1 9.6 0.0 4.1 6 0 0 6 6 6 0 Kelch motif AMP-binding PF00501.23 KFM09650.1 - 4e-74 249.4 0.0 4.8e-74 249.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFM09650.1 - 5.8e-06 27.1 0.1 1.2e-05 26.1 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Thioredoxin_8 PF13905.1 KFM09651.1 - 8.5e-23 80.2 0.0 1.4e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KFM09651.1 - 9e-07 29.0 0.0 1.6e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 KFM09651.1 - 5.5e-05 22.7 0.0 7.9e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Redoxin TraF PF13728.1 KFM09651.1 - 0.0054 16.2 0.3 0.071 12.5 0.0 2.6 3 1 1 4 4 4 1 F plasmid transfer operon protein Thioredoxin PF00085.15 KFM09651.1 - 0.017 14.7 0.0 0.1 12.2 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_7 PF13899.1 KFM09651.1 - 0.067 13.2 0.1 0.6 10.1 0.0 2.5 2 1 0 2 2 2 0 Thioredoxin-like efThoc1 PF11957.3 KFM09653.1 - 0.045 12.2 1.6 0.045 12.2 0.7 1.3 1 1 0 1 1 1 0 THO complex subunit 1 transcription elongation factor TPR_MLP1_2 PF07926.7 KFM09653.1 - 0.05 13.3 6.9 0.072 12.8 4.8 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein MRP-S26 PF14943.1 KFM09653.1 - 0.07 12.6 6.3 0.083 12.4 4.4 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 V_ATPase_I PF01496.14 KFM09653.1 - 0.4 8.4 2.7 0.45 8.3 1.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rpr2 PF04032.11 KFM09654.1 - 0.12 12.2 0.6 0.13 12.1 0.4 1.4 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF4653 PF15546.1 KFM09654.1 - 1.4 8.1 5.0 1.8 7.8 3.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4653) 7tm_1 PF00001.16 KFM09655.1 - 2.7e-35 121.7 24.2 3.3e-35 121.4 16.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM09655.1 - 1e-11 44.4 23.2 1.3e-11 44.1 16.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx TraS PF10624.4 KFM09655.1 - 0.78 9.2 5.8 0.11 12.0 0.8 2.0 2 0 0 2 2 2 0 Plasmid conjugative transfer entry exclusion protein TraS PBC PF03792.8 KFM09656.1 - 2e-70 236.3 0.0 2.9e-70 235.8 0.0 1.2 1 0 0 1 1 1 1 PBC domain Homeobox PF00046.24 KFM09656.1 - 1.8e-18 65.8 0.5 3.7e-18 64.8 0.3 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFM09656.1 - 3.1e-15 55.5 0.0 1.8e-14 53.1 0.0 2.1 2 0 0 2 2 2 1 Homeobox KN domain DUF1319 PF07028.6 KFM09656.1 - 0.014 15.5 0.3 0.029 14.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) Homez PF11569.3 KFM09656.1 - 0.016 14.2 0.0 0.043 12.8 0.0 1.7 1 1 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez HTH_3 PF01381.17 KFM09656.1 - 0.018 14.9 0.0 0.042 13.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix Sec15 PF04091.7 KFM09656.1 - 0.021 14.1 0.1 0.032 13.5 0.1 1.3 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like HTH_19 PF12844.2 KFM09656.1 - 0.027 14.5 0.0 0.095 12.7 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain CENP-B_N PF04218.8 KFM09656.1 - 0.047 13.1 0.2 0.57 9.6 0.0 2.3 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain NUC130_3NT PF08158.7 KFM09656.1 - 0.15 12.3 0.4 7.9 6.8 0.0 3.2 3 1 0 3 3 3 0 NUC130/3NT domain MADF_DNA_bdg PF10545.4 KFM09656.1 - 4.1 7.6 5.5 19 5.4 0.1 3.0 1 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like MIS13 PF08202.6 KFM09657.1 - 4.8e-25 88.2 0.7 9.3e-25 87.2 0.5 1.4 1 1 0 1 1 1 1 Mis12-Mtw1 protein family Sec1 PF00995.18 KFM09657.1 - 0.053 12.1 0.0 0.081 11.5 0.0 1.2 1 0 0 1 1 1 0 Sec1 family Cor1 PF04803.7 KFM09657.1 - 0.31 10.8 3.3 2.4 7.9 0.0 2.7 3 0 0 3 3 3 0 Cor1/Xlr/Xmr conserved region E1-E2_ATPase PF00122.15 KFM09658.1 - 1e-22 80.3 0.0 2.3e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 KFM09658.1 - 2.1e-21 76.9 0.0 1.3e-19 71.1 0.0 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFM09658.1 - 2.8e-20 73.6 0.0 1.1e-19 71.7 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFM09658.1 - 1.8e-06 27.7 0.0 4.2e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFM09658.1 - 0.00079 19.0 0.0 0.05 13.1 0.0 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Rotamase PF00639.16 KFM09659.1 - 2.4e-23 82.6 0.1 5.1e-23 81.6 0.1 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 KFM09659.1 - 1.7e-19 70.1 0.0 3.6e-19 69.1 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 KFM09659.1 - 2.1e-09 37.0 0.2 4.8e-09 35.9 0.0 1.7 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.1 KFM09659.1 - 0.00021 21.9 0.0 0.00028 21.5 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Atg8 PF02991.11 KFM09660.1 - 2.3e-34 117.4 0.1 2.5e-34 117.3 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 KFM09660.1 - 6.1e-06 26.3 0.0 7.1e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 OLF PF02191.11 KFM09661.1 - 8.5e-94 313.4 2.9 1.1e-93 313.0 2.0 1.2 1 0 0 1 1 1 1 Olfactomedin-like domain Noelin-1 PF12308.3 KFM09661.1 - 8.6e-49 163.5 4.4 1.5e-47 159.5 0.5 3.1 3 0 0 3 3 3 1 Neurogenesis glycoprotein DASH_Dam1 PF08653.5 KFM09661.1 - 0.18 11.5 0.7 18 5.1 0.0 2.7 2 0 0 2 2 2 0 DASH complex subunit Dam1 DUF310 PF03750.8 KFM09661.1 - 0.61 10.2 2.4 4.1 7.6 0.6 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF310) MitMem_reg PF13012.1 KFM09661.1 - 2.7 8.1 5.7 2 8.5 2.4 1.9 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function Brix PF04427.13 KFM09662.1 - 1.4e-19 70.5 1.2 1.6e-19 70.3 0.8 1.0 1 0 0 1 1 1 1 Brix domain CUE PF02845.11 KFM09662.1 - 0.17 11.4 0.6 13 5.3 0.1 2.6 2 0 0 2 2 2 0 CUE domain eIF3g PF12353.3 KFM09663.1 - 5.2e-43 146.0 1.8 8.5e-43 145.3 1.3 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 KFM09663.1 - 6.2e-19 67.4 0.0 1.7e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM09663.1 - 1.1e-14 54.1 0.1 4e-14 52.3 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM09663.1 - 6.7e-07 29.0 0.0 1.3e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 KFM09663.1 - 0.037 14.0 0.0 0.078 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA binding domain DUF1247 PF06851.6 KFM09663.1 - 0.096 12.3 0.1 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1247) DNA_methylase PF00145.12 KFM09664.1 - 2.4e-33 115.6 0.0 2.8e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.13 KFM09665.1 - 8.4e-42 141.6 0.0 4.5e-23 81.2 0.0 2.6 2 0 0 2 2 2 2 BAH domain zf-CXXC PF02008.15 KFM09665.1 - 2.2e-15 56.2 21.2 6.1e-15 54.7 14.7 1.8 1 0 0 1 1 1 1 CXXC zinc finger domain DNMT1-RFD PF12047.3 KFM09665.1 - 7.3e-14 51.6 0.2 6.8e-13 48.5 0.1 2.4 2 0 0 2 2 2 1 Cytosine specific DNA methyltransferase replication foci domain DS PF01916.12 KFM09666.1 - 2.5e-28 99.0 0.0 2.7e-28 98.9 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Ras PF00071.17 KFM09667.1 - 6e-13 48.4 0.1 6.5e-13 48.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM09667.1 - 7.3e-06 26.4 0.0 7.3e-06 26.4 0.0 1.0 1 0 0 1 1 1 1 Miro-like protein MobB PF03205.9 KFM09667.1 - 0.00012 21.7 0.1 0.00013 21.6 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 KFM09667.1 - 0.00019 21.5 0.0 0.00019 21.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 KFM09667.1 - 0.0057 15.6 0.0 0.0062 15.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 KFM09667.1 - 0.0058 16.6 0.0 0.0058 16.6 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.7 KFM09667.1 - 0.008 15.3 0.0 0.0084 15.2 0.0 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 KFM09667.1 - 0.0096 15.4 0.0 0.01 15.3 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 KFM09667.1 - 0.011 15.1 0.0 0.013 14.9 0.0 1.0 1 0 0 1 1 1 0 AAA-like domain Sigma54_activat PF00158.21 KFM09667.1 - 0.013 14.9 0.0 0.013 14.9 0.0 1.1 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.24 KFM09667.1 - 0.018 15.2 0.0 0.018 15.2 0.0 1.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFM09667.1 - 0.025 14.2 0.0 0.029 14.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 KFM09667.1 - 0.029 13.9 0.0 0.034 13.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KFM09667.1 - 0.039 13.6 0.0 0.039 13.6 0.0 1.1 1 0 0 1 1 1 0 Archaeal ATPase AAA_29 PF13555.1 KFM09667.1 - 0.042 13.3 0.0 0.42 10.1 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain NACHT PF05729.7 KFM09667.1 - 0.046 13.3 0.0 0.047 13.3 0.0 1.1 1 0 0 1 1 1 0 NACHT domain ATP_bind_1 PF03029.12 KFM09667.1 - 0.053 13.0 0.0 0.059 12.8 0.0 1.0 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 KFM09667.1 - 0.063 13.2 0.0 0.063 13.2 0.0 1.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase NTPase_1 PF03266.10 KFM09667.1 - 0.071 12.8 0.1 0.084 12.5 0.0 1.1 1 0 0 1 1 1 0 NTPase cobW PF02492.14 KFM09667.1 - 0.072 12.5 0.0 0.072 12.5 0.0 1.1 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.13 KFM09667.1 - 0.085 11.8 0.0 0.085 11.8 0.0 1.1 1 0 0 1 1 1 0 Septin SNF2_N PF00176.18 KFM09668.1 - 2.3e-107 358.2 2.0 3.9e-107 357.5 1.4 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Linker_histone PF00538.14 KFM09668.1 - 2.9e-15 56.0 0.3 1.1e-14 54.2 0.2 2.1 1 0 0 1 1 1 1 linker histone H1 and H5 family PHD PF00628.24 KFM09668.1 - 2e-06 27.4 7.2 2e-06 27.4 5.0 3.7 3 1 0 3 3 2 1 PHD-finger zf-C3HC4_2 PF13923.1 KFM09668.1 - 9.8e-06 25.5 10.7 9.8e-06 25.5 7.5 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM09668.1 - 1.4e-05 24.8 9.2 1.4e-05 24.8 6.4 3.5 3 0 0 3 3 3 1 Ring finger domain Helicase_C PF00271.26 KFM09668.1 - 0.00028 20.7 0.0 0.00089 19.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.1 KFM09668.1 - 0.0016 18.1 3.4 0.0016 18.1 2.3 2.8 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.20 KFM09668.1 - 0.0018 17.8 9.8 0.0018 17.8 6.8 2.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM09668.1 - 0.0028 17.3 9.4 0.0028 17.3 6.5 2.9 2 1 0 2 2 2 1 zinc-RING finger domain TPR_7 PF13176.1 KFM09668.1 - 0.014 15.1 0.2 0.053 13.3 0.1 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 KFM09668.1 - 0.027 14.3 1.1 0.12 12.3 0.6 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat PEP-utilisers_N PF05524.8 KFM09668.1 - 0.041 13.6 2.8 0.14 11.9 0.6 2.6 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal F-box PF00646.28 KFM09669.1 - 2.2e-07 30.3 1.1 6.3e-07 28.9 0.7 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KFM09669.1 - 9.9e-07 28.3 0.2 2.8e-06 26.9 0.2 1.8 1 0 0 1 1 1 1 F-box-like zf-TRAF PF02176.13 KFM09669.1 - 0.017 15.4 3.3 0.017 15.4 2.3 5.0 6 1 1 7 7 7 0 TRAF-type zinc finger DSPc PF00782.15 KFM09670.1 - 7.2e-14 51.5 0.0 1.4e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.8 KFM09670.1 - 0.012 14.9 0.0 0.031 13.6 0.0 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family CDKN3 PF05706.7 KFM09670.1 - 0.042 13.2 0.0 0.069 12.6 0.0 1.4 1 1 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 KFM09670.1 - 0.043 13.8 0.0 0.063 13.3 0.0 1.4 1 1 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.22 KFM09670.1 - 0.1 11.9 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase AlaDh_PNT_N PF05222.10 KFM09670.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, N-terminal domain EF-hand_2 PF09068.6 KFM09671.1 - 6.5e-46 155.5 1.5 1.2e-45 154.6 1.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_3 PF09069.6 KFM09671.1 - 4.7e-38 129.1 0.0 1.2e-37 127.8 0.0 1.7 1 0 0 1 1 1 1 EF-hand ZZ PF00569.12 KFM09671.1 - 4.4e-22 77.3 5.5 4.4e-22 77.3 3.8 2.0 2 0 0 2 2 2 1 Zinc finger, ZZ type WW PF00397.21 KFM09671.1 - 0.32 10.9 2.0 0.57 10.1 1.4 1.4 1 0 0 1 1 1 0 WW domain Spectrin PF00435.16 KFM09672.1 - 9.9e-17 61.1 19.3 6.4e-11 42.4 4.1 3.0 2 1 1 3 3 3 2 Spectrin repeat DUF948 PF06103.6 KFM09672.1 - 0.0056 16.5 6.0 1.1 9.1 0.3 4.0 3 1 1 4 4 4 1 Bacterial protein of unknown function (DUF948) DUF4398 PF14346.1 KFM09672.1 - 0.0068 16.4 2.7 0.02 14.9 1.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4398) DUF1995 PF09353.5 KFM09672.1 - 0.017 14.7 0.5 3.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1995) NPV_P10 PF05531.7 KFM09672.1 - 0.049 13.8 13.9 0.4 10.9 0.3 4.2 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF3201 PF11447.3 KFM09672.1 - 0.062 12.7 1.1 0.13 11.6 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3201) EFhand_Ca_insen PF08726.5 KFM09672.1 - 0.085 12.8 1.6 0.16 11.9 0.1 2.2 2 1 0 2 2 2 0 Ca2+ insensitive EF hand AAA_13 PF13166.1 KFM09672.1 - 0.32 9.4 10.1 0.55 8.6 2.4 2.2 2 0 0 2 2 2 0 AAA domain Phage_lysis PF03245.8 KFM09672.1 - 0.59 10.1 6.5 3.6 7.5 1.0 2.7 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein RmuC PF02646.11 KFM09672.1 - 0.62 8.8 12.6 0.063 12.0 1.3 3.0 3 0 0 3 3 3 0 RmuC family DIL PF01843.14 KFM09672.1 - 1.5 8.7 6.3 8.1 6.3 0.1 2.9 3 1 1 4 4 4 0 DIL domain DUF3702 PF12486.3 KFM09672.1 - 1.8 8.2 11.8 0.46 10.1 1.8 3.0 2 2 1 3 3 3 0 ImpA domain protein Occludin_ELL PF07303.8 KFM09672.1 - 2.4 8.9 13.1 34 5.2 0.7 3.6 3 1 0 3 3 3 0 Occludin homology domain Atg14 PF10186.4 KFM09672.1 - 6 5.7 10.3 1.1 8.1 0.8 2.3 2 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Rapamycin_bind PF08771.6 KFM09672.1 - 7.3 6.7 9.8 5 7.2 0.8 3.2 3 1 0 3 3 3 0 Rapamycin binding domain Spectrin PF00435.16 KFM09673.1 - 3.6e-45 152.5 83.5 1.2e-14 54.4 2.8 8.0 8 1 0 8 8 8 7 Spectrin repeat CH PF00307.26 KFM09673.1 - 6.8e-37 125.8 0.1 1.3e-19 70.2 0.0 3.7 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFM09673.1 - 7.7e-08 31.8 0.0 6e-05 22.6 0.0 3.1 2 0 0 2 2 2 2 CAMSAP CH domain SNARE PF05739.14 KFM09674.1 - 2.1e-14 52.9 1.3 2.1e-14 52.9 0.9 2.5 2 1 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 KFM09674.1 - 5.3e-07 29.7 2.6 5.3e-07 29.7 1.8 2.5 2 1 0 2 2 2 1 Syntaxin Leu_zip PF15294.1 KFM09674.1 - 0.01 14.9 2.3 0.01 14.9 1.6 2.4 2 1 0 2 2 2 0 Leucine zipper DUF1217 PF06748.7 KFM09674.1 - 0.011 15.8 0.1 0.035 14.1 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1217) Toprim_Crpt PF13342.1 KFM09674.1 - 0.018 14.6 0.1 0.039 13.5 0.0 1.6 1 0 0 1 1 1 0 C-terminal repeat of topoisomerase MCPsignal PF00015.16 KFM09674.1 - 0.042 13.4 2.3 0.14 11.6 0.2 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain FUN14 PF04930.10 KFM09674.1 - 0.12 12.6 0.5 0.63 10.3 0.0 2.3 2 1 0 2 2 2 0 FUN14 family DivIC PF04977.10 KFM09674.1 - 0.17 11.3 5.2 0.13 11.7 0.3 2.9 3 0 0 3 3 3 0 Septum formation initiator TMF_DNA_bd PF12329.3 KFM09674.1 - 0.2 11.4 3.5 0.21 11.3 0.2 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding HisKA_3 PF07730.8 KFM09674.1 - 0.22 11.8 2.4 5.6 7.3 0.1 3.4 2 2 1 3 3 3 0 Histidine kinase KxDL PF10241.4 KFM09674.1 - 0.45 10.4 6.1 0.16 11.9 0.6 2.8 3 1 0 3 3 3 0 Uncharacterized conserved protein Spectrin PF00435.16 KFM09674.1 - 0.49 10.7 9.1 0.27 11.5 1.7 2.8 2 2 0 2 2 2 0 Spectrin repeat FlaC_arch PF05377.6 KFM09674.1 - 1.7 8.6 7.4 1.5 8.7 0.2 3.7 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) Occludin_ELL PF07303.8 KFM09674.1 - 5.3 7.8 7.5 1.5 9.6 0.8 2.7 2 1 0 2 2 2 0 Occludin homology domain RVT_1 PF00078.22 KFM09676.1 - 0.012 15.0 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) fn3 PF00041.16 KFM09677.1 - 1.2e-31 108.6 13.7 2.3e-10 40.4 0.0 5.4 6 0 0 6 6 6 3 Fibronectin type III domain Interfer-bind PF09294.5 KFM09677.1 - 3.8e-07 30.1 0.1 0.045 13.7 0.3 3.7 3 0 0 3 3 3 2 Interferon-alpha/beta receptor, fibronectin type III Pkinase PF00069.20 KFM09679.1 - 1.7e-20 73.2 0.0 2.2e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM09679.1 - 2.1e-10 40.0 0.0 1.1e-09 37.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase EcKinase PF02958.15 KFM09679.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase WD-3 PF09765.4 KFM09680.1 - 1.7e-108 362.3 0.1 2e-108 362.1 0.1 1.0 1 0 0 1 1 1 1 WD-repeat region FANCL_C PF11793.3 KFM09680.1 - 7.8e-31 105.8 3.9 1.5e-30 104.9 2.7 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.1 KFM09680.1 - 1.5e-05 24.7 4.7 1.5e-05 24.7 3.3 1.8 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 KFM09680.1 - 0.00094 19.2 0.9 0.0029 17.6 0.6 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KFM09680.1 - 0.054 13.3 3.4 0.24 11.2 2.4 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 KFM09680.1 - 1 9.4 4.3 0.64 10.0 1.1 2.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.21 KFM09681.1 - 1.6e-24 84.7 56.9 1.8e-05 24.8 2.0 7.6 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM09681.1 - 1.7e-16 59.5 55.1 2.2e-07 30.8 0.9 9.0 9 0 0 9 9 8 4 Zinc-finger double domain zf-C2H2_6 PF13912.1 KFM09681.1 - 9.3e-09 34.8 15.1 1.9e-06 27.5 0.2 7.0 9 0 0 9 9 7 4 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KFM09681.1 - 6.4e-08 32.4 62.9 0.018 15.3 0.3 7.8 8 0 0 8 8 7 5 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KFM09681.1 - 0.0021 18.1 2.8 0.0021 18.1 1.9 5.4 6 0 0 6 6 4 2 C2H2-type zinc-finger domain Sigma70_ner PF04546.8 KFM09681.1 - 0.026 14.1 10.1 0.041 13.5 7.0 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Daxx PF03344.10 KFM09681.1 - 0.047 12.1 21.0 0.068 11.6 14.6 1.2 1 0 0 1 1 1 0 Daxx Family GAGA PF09237.6 KFM09681.1 - 0.052 13.1 6.9 2 8.0 0.2 2.9 2 1 0 2 2 2 0 GAGA factor Nop14 PF04147.7 KFM09681.1 - 0.059 11.3 14.3 0.079 10.8 9.9 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4329 PF14220.1 KFM09681.1 - 0.07 13.0 2.8 0.088 12.7 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4329) CobT PF06213.7 KFM09681.1 - 0.16 11.0 19.3 0.26 10.3 13.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT IFT57 PF10498.4 KFM09681.1 - 0.37 9.4 8.4 0.53 8.9 5.8 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Prothymosin PF03247.9 KFM09681.1 - 0.46 10.6 33.3 0.91 9.7 23.1 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family RAB3GAP2_C PF14656.1 KFM09681.1 - 0.61 8.1 2.0 0.86 7.6 1.4 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus eIF-3c_N PF05470.7 KFM09681.1 - 0.63 8.0 6.4 0.88 7.5 4.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Astro_capsid PF03115.9 KFM09681.1 - 0.89 7.7 3.3 1.2 7.2 2.3 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Pox_Ag35 PF03286.9 KFM09681.1 - 1.2 8.5 8.4 2.4 7.6 5.8 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.9 KFM09681.1 - 1.4 6.8 11.5 2 6.3 8.0 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 KFM09681.1 - 2.5 7.2 20.4 0.12 11.6 5.8 2.3 2 0 0 2 2 2 0 NOA36 protein TFIIF_alpha PF05793.7 KFM09681.1 - 2.7 6.2 17.9 5.1 5.3 12.4 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RRN3 PF05327.6 KFM09681.1 - 3 5.8 7.6 4.5 5.2 5.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 zf-C2H2_jaz PF12171.3 KFM09681.1 - 3.8 7.7 44.8 0.55 10.4 1.4 6.3 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding Nucleoplasmin PF03066.10 KFM09681.1 - 6.4 6.2 20.3 12 5.3 14.0 1.4 1 0 0 1 1 1 0 Nucleoplasmin DUF1510 PF07423.6 KFM09681.1 - 6.9 5.9 13.9 11 5.2 9.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) zf-C2H2_7 PF15269.1 KFM09681.1 - 9.2 6.2 25.8 0.53 10.2 1.0 4.1 3 2 1 4 4 4 0 Zinc-finger RHD PF00554.17 KFM09682.1 - 5.6e-77 257.2 0.0 2.1e-76 255.3 0.0 1.9 2 0 0 2 2 2 1 Rel homology domain (RHD) DUF2673 PF10880.3 KFM09682.1 - 0.049 13.6 1.7 0.25 11.4 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2673) TPD PF14811.1 KFM09683.1 - 0.084 12.3 0.1 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function TPD sequence-motif TFIID_20kDa PF03847.8 KFM09683.1 - 0.44 10.8 2.6 70 3.8 0.0 3.9 4 0 0 4 4 4 0 Transcription initiation factor TFIID subunit A Peroxin-13_N PF04088.8 KFM09684.1 - 3.2e-48 163.6 0.1 4.7e-48 163.1 0.1 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_9 PF14604.1 KFM09684.1 - 3.5e-10 39.3 0.1 9.1e-10 37.9 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 KFM09684.1 - 2.7e-07 29.8 0.0 4.9e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFM09684.1 - 4e-05 23.0 0.0 7.7e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Cadherin PF00028.12 KFM09685.1 - 1.6e-26 92.3 0.5 2.7e-17 62.7 0.0 2.4 2 1 0 2 2 2 2 Cadherin domain Cadherin_pro PF08758.6 KFM09685.1 - 0.021 14.5 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Cadherin prodomain like Membrane_bind PF14564.1 KFM09685.1 - 0.09 12.9 0.2 0.23 11.6 0.0 1.8 2 0 0 2 2 2 0 Membrane binding Cadherin PF00028.12 KFM09687.1 - 1.8e-08 34.4 1.0 3.4e-08 33.6 0.1 1.9 2 1 0 2 2 2 1 Cadherin domain DUF3377 PF11857.3 KFM09687.1 - 0.0024 17.4 4.3 0.012 15.2 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3377) DUF2887 PF11103.3 KFM09687.1 - 0.0027 17.3 0.8 0.004 16.8 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2887) Amnionless PF14828.1 KFM09687.1 - 0.016 13.7 0.5 0.029 12.8 0.4 1.5 1 1 0 1 1 1 0 Amnionless EphA2_TM PF14575.1 KFM09687.1 - 0.06 13.7 0.1 0.31 11.4 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Potass_KdpF PF09604.5 KFM09687.1 - 2 8.3 8.5 4 7.3 5.9 1.5 1 0 0 1 1 1 0 F subunit of K+-transporting ATPase (Potass_KdpF) AHSA1 PF08327.6 KFM09688.1 - 2.1e-16 60.1 0.0 4.3e-16 59.1 0.0 1.5 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Aha1_N PF09229.6 KFM09688.1 - 6.8e-14 51.8 1.0 1.6e-13 50.6 0.2 1.9 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal CRM1_C PF08767.6 KFM09689.1 - 3.4e-138 459.9 8.7 1.7e-137 457.6 0.9 2.6 2 0 0 2 2 2 2 CRM1 C terminal Xpo1 PF08389.7 KFM09689.1 - 5.7e-38 130.1 3.8 5.7e-38 130.1 2.6 5.7 7 1 0 7 7 7 1 Exportin 1-like protein IBN_N PF03810.14 KFM09689.1 - 1.4e-07 31.3 0.1 7.8e-07 28.9 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain UME PF08064.8 KFM09689.1 - 6.3 6.8 9.9 13 5.8 0.0 5.4 5 0 0 5 5 5 0 UME (NUC010) domain UPF0564 PF10595.4 KFM09690.1 - 1.1e-76 258.1 46.1 1.1e-76 258.1 31.9 2.2 2 0 0 2 2 2 1 Uncharacterised protein family UPF0564 Cpn60_TCP1 PF00118.19 KFM09691.1 - 1e-145 486.0 13.6 1.2e-145 485.9 9.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.7 KFM09691.1 - 0.0097 15.3 0.0 0.023 14.1 0.0 1.6 1 0 0 1 1 1 1 Phage Tail Protein X LRR_8 PF13855.1 KFM09692.1 - 2.5e-33 113.6 35.8 1.7e-11 43.7 0.6 4.9 2 2 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 KFM09692.1 - 3.8e-16 58.3 32.3 1.3e-07 31.0 2.0 6.7 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) fn3 PF00041.16 KFM09692.1 - 3e-11 43.2 0.2 7.9e-11 41.9 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III domain LRR_1 PF00560.28 KFM09692.1 - 1.2e-06 27.7 31.3 1.5 9.1 0.2 9.8 10 0 0 10 10 10 4 Leucine Rich Repeat LRR_6 PF13516.1 KFM09692.1 - 2.8e-05 23.7 22.3 7.4 6.9 0.1 8.5 7 1 1 8 8 8 3 Leucine Rich repeat LRR_7 PF13504.1 KFM09692.1 - 0.02 14.9 25.6 16 6.2 0.0 8.8 9 0 0 9 9 9 0 Leucine rich repeat FERM_M PF00373.13 KFM09693.1 - 2.4e-41 140.8 0.2 5.5e-41 139.6 0.1 1.6 1 0 0 1 1 1 1 FERM central domain PH PF00169.24 KFM09693.1 - 2.1e-07 31.0 0.0 8.3e-07 29.1 0.0 2.0 1 0 0 1 1 1 1 PH domain FERM_N PF09379.5 KFM09693.1 - 1.7e-05 24.7 0.0 0.00018 21.4 0.0 2.6 2 1 0 2 2 2 1 FERM N-terminal domain TGFb_propeptide PF00688.13 KFM09694.1 - 2.9e-46 157.6 1.7 4.1e-46 157.2 1.2 1.2 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.15 KFM09694.1 - 1.1e-41 141.3 0.8 2e-41 140.5 0.6 1.4 1 0 0 1 1 1 1 Transforming growth factor beta like domain DUF908 PF06012.7 KFM09694.1 - 0.013 14.8 0.1 0.019 14.3 0.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) FMN_dh PF01070.13 KFM09696.1 - 5.7e-132 439.8 4.7 6.5e-131 436.4 3.2 1.9 1 1 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 KFM09696.1 - 2e-05 23.6 2.7 2.9e-05 23.1 0.1 2.3 2 1 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 KFM09696.1 - 3.5e-05 22.9 0.5 0.21 10.6 0.1 2.6 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.12 KFM09696.1 - 5.6e-05 22.2 0.1 9.7e-05 21.4 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 KFM09696.1 - 0.00042 19.6 0.3 0.0047 16.2 0.0 2.3 1 1 1 2 2 2 1 Histidine biosynthesis protein DHO_dh PF01180.16 KFM09696.1 - 0.0045 15.9 0.4 0.011 14.6 0.0 1.8 3 0 0 3 3 3 1 Dihydroorotate dehydrogenase NMO PF03060.10 KFM09696.1 - 0.01 15.0 1.4 0.018 14.2 1.0 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase TMP-TENI PF02581.12 KFM09696.1 - 0.017 14.2 0.7 0.25 10.4 0.0 2.7 3 0 0 3 3 3 0 Thiamine monophosphate synthase/TENI CdhD PF03599.11 KFM09696.1 - 0.037 12.5 0.0 0.057 11.9 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit PA PF02225.17 KFM09696.1 - 0.057 13.1 0.3 9.6 5.9 0.1 2.8 2 1 1 3 3 3 0 PA domain Thioredoxin PF00085.15 KFM09697.1 - 8.3e-14 51.1 0.0 1e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin PI-PLC-X PF00388.14 KFM09698.1 - 3.1e-65 218.0 0.0 3.1e-65 218.0 0.0 2.6 3 1 0 3 3 3 1 Phosphatidylinositol-specific phospholipase C, X domain PLC-beta_C PF08703.5 KFM09698.1 - 2.3e-57 193.7 47.2 2.3e-57 193.7 32.7 2.8 3 0 0 3 3 3 1 PLC-beta C terminal PI-PLC-Y PF00387.14 KFM09698.1 - 8.8e-45 151.4 2.0 8.8e-45 151.4 1.4 4.0 3 1 1 4 4 4 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 KFM09698.1 - 6.7e-24 83.7 0.1 6.7e-24 83.7 0.0 3.6 3 0 0 3 3 3 1 Phosphoinositide-specific phospholipase C, efhand-like PI-PLC-X PF00388.14 KFM09699.1 - 1.9e-66 221.9 0.8 4.1e-66 220.8 0.0 2.1 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KFM09699.1 - 9.6e-45 151.3 0.6 9.6e-45 151.3 0.4 3.8 4 1 1 5 5 5 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 KFM09699.1 - 2.8e-24 84.9 2.4 8.1e-24 83.4 0.0 3.0 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like DUF1154 PF06631.6 KFM09699.1 - 4.7e-19 67.7 11.7 4.7e-19 67.7 8.1 3.4 4 0 0 4 4 4 1 Protein of unknown function (DUF1154) C2 PF00168.25 KFM09699.1 - 9e-11 41.4 0.0 2.5e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.1 KFM09699.1 - 0.042 13.9 2.0 0.29 11.3 0.1 2.9 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_6 PF13405.1 KFM09699.1 - 0.078 12.9 2.6 0.31 11.0 0.3 2.7 2 0 0 2 2 2 0 EF-hand domain Pkinase PF00069.20 KFM09700.1 - 1.6e-69 233.9 0.0 2.3e-69 233.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM09700.1 - 6.8e-45 153.1 0.0 9.7e-45 152.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 KFM09700.1 - 7.6e-14 51.8 0.1 3.2e-13 49.8 0.1 2.2 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 KFM09700.1 - 2.6e-08 33.2 0.0 6e-08 31.9 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KFM09700.1 - 0.016 14.9 0.1 2.3 7.8 0.0 3.2 1 1 2 3 3 3 0 Phosphotransferase enzyme family adh_short PF00106.20 KFM09701.1 - 5e-11 42.7 0.1 1.2e-09 38.2 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase DUF1776 PF08643.5 KFM09701.1 - 7.6e-07 28.5 0.0 8.7e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) HMG_box PF00505.14 KFM09701.1 - 0.00046 20.4 0.8 0.0019 18.4 0.1 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box Ank_2 PF12796.2 KFM09702.1 - 7e-69 228.2 7.2 2.8e-21 75.6 0.1 5.5 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KFM09702.1 - 1.9e-61 200.9 11.2 1.5e-10 40.3 0.0 10.0 10 0 0 10 10 10 8 Ankyrin repeat Ank_4 PF13637.1 KFM09702.1 - 2.4e-48 161.6 11.7 2.2e-15 56.6 0.0 8.5 5 1 4 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM09702.1 - 1.4e-45 152.3 18.4 8.1e-11 41.7 0.1 9.5 5 3 6 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM09702.1 - 1.3e-44 145.7 8.9 1.4e-07 31.0 0.0 10.4 11 0 0 11 11 11 8 Ankyrin repeat EF-hand_6 PF13405.1 KFM09702.1 - 0.09 12.7 0.1 0.45 10.5 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain SNARE PF05739.14 KFM09703.1 - 1e-18 66.7 14.2 6.1e-13 48.2 3.7 2.2 2 0 0 2 2 2 2 SNARE domain SNAP-25 PF00835.14 KFM09703.1 - 4.3e-18 65.8 0.1 9.5e-18 64.7 0.1 1.6 1 0 0 1 1 1 1 SNAP-25 family V-SNARE_C PF12352.3 KFM09703.1 - 0.033 14.2 2.7 0.34 11.0 0.0 2.7 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus Syntaxin PF00804.20 KFM09703.1 - 0.11 12.6 1.1 9.1 6.5 0.0 2.3 2 0 0 2 2 2 0 Syntaxin DUF4200 PF13863.1 KFM09703.1 - 0.12 12.3 3.1 1.4 8.8 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) CR6_interact PF10147.4 KFM09703.1 - 0.12 11.6 2.0 0.52 9.6 0.1 2.0 2 0 0 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 LTXXQ PF07813.7 KFM09703.1 - 0.55 10.7 2.9 7.1 7.1 0.6 2.5 2 1 0 2 2 2 0 LTXXQ motif family protein BLOC1_2 PF10046.4 KFM09703.1 - 0.72 10.0 3.2 9 6.5 0.3 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cpn60_TCP1 PF00118.19 KFM09704.1 - 2.1e-83 280.6 0.0 2.7e-83 280.2 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family EGF PF00008.22 KFM09706.1 - 2.2e-79 260.7 281.7 1.4e-09 37.7 5.6 19.7 19 1 0 19 19 19 14 EGF-like domain MNNL PF07657.8 KFM09706.1 - 1.7e-30 104.7 2.6 1.7e-30 104.7 1.8 6.4 7 0 0 7 7 7 1 N terminus of Notch ligand DSL PF01414.14 KFM09706.1 - 1.6e-27 95.2 8.3 1.6e-27 95.2 5.7 15.6 14 3 3 17 17 17 2 Delta serrate ligand EGF_2 PF07974.8 KFM09706.1 - 2.3e-25 88.4 326.1 0.00034 20.7 7.4 19.8 19 0 0 19 19 19 15 EGF-like domain hEGF PF12661.2 KFM09706.1 - 4.2e-20 70.3 189.8 0.012 15.5 2.5 19.7 19 0 0 19 19 19 14 Human growth factor-like EGF EGF_CA PF07645.10 KFM09706.1 - 6.6e-07 29.2 25.0 4.5e-05 23.3 6.0 19.4 10 5 11 21 21 21 11 Calcium-binding EGF domain Peptidase_S49_N PF08496.5 KFM09706.1 - 0.43 10.3 0.3 0.69 9.6 0.2 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PHR PF08005.7 KFM09707.1 - 5e-45 153.3 0.6 8.7e-45 152.5 0.4 1.4 1 0 0 1 1 1 1 PHR domain BTB PF00651.26 KFM09707.1 - 5.2e-24 84.3 0.0 4e-23 81.5 0.0 2.3 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.10 KFM09707.1 - 3.2e-07 30.1 3.3 4e-07 29.8 0.8 2.2 2 1 0 2 2 2 1 BTB And C-terminal Kelch Aminotran_1_2 PF00155.16 KFM09708.1 - 7.3e-57 192.9 0.0 8.5e-57 192.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KFM09708.1 - 2.8e-05 23.4 0.0 4.4e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Asparaginase_2 PF01112.13 KFM09709.1 - 6.9e-42 143.2 0.1 1.2e-41 142.5 0.1 1.3 1 0 0 1 1 1 1 Asparaginase NUC153 PF08159.7 KFM09710.1 - 4.1e-11 42.2 12.2 2.1e-10 39.9 0.7 3.8 3 0 0 3 3 3 2 NUC153 domain Methyltransf_11 PF08241.7 KFM09711.1 - 9.3e-21 74.1 0.0 1.4e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFM09711.1 - 2.3e-14 53.4 0.0 3.4e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFM09711.1 - 6e-13 48.6 0.0 1.2e-12 47.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFM09711.1 - 1e-11 45.0 0.0 1.9e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFM09711.1 - 1.5e-11 44.6 0.0 2.3e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFM09711.1 - 9.3e-09 34.7 0.0 1.5e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KFM09711.1 - 5.1e-06 27.0 0.0 1.2e-05 25.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 KFM09711.1 - 8.6e-05 21.0 0.0 0.00011 20.6 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.9 KFM09711.1 - 0.00014 21.3 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 KFM09711.1 - 0.00092 18.6 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_26 PF13659.1 KFM09711.1 - 0.0013 18.7 0.0 0.0035 17.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 KFM09711.1 - 0.032 13.6 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) DUF633 PF04816.7 KFM09711.1 - 0.1 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF633) Pox_MCEL PF03291.11 KFM09711.1 - 0.12 11.1 0.0 7.3 5.3 0.0 2.1 2 0 0 2 2 2 0 mRNA capping enzyme LRR_8 PF13855.1 KFM09712.1 - 7.3e-31 105.7 31.2 2.9e-12 46.1 2.2 5.2 5 0 0 5 5 5 4 Leucine rich repeat LRR_4 PF12799.2 KFM09712.1 - 4.2e-21 74.1 43.0 3.4e-08 32.9 2.0 7.2 2 2 6 8 8 8 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM09712.1 - 1.6e-13 48.6 35.2 0.059 13.4 0.3 11.3 11 0 0 11 11 11 4 Leucine Rich Repeat LRR_5 PF13306.1 KFM09712.1 - 7.1e-08 32.2 0.0 0.00016 21.3 0.0 3.6 1 1 3 4 4 4 2 Leucine rich repeats (6 copies) LRR_9 PF14580.1 KFM09712.1 - 7.8e-06 25.5 8.6 0.011 15.3 1.6 3.4 2 1 1 3 3 3 3 Leucine-rich repeat LRR_7 PF13504.1 KFM09712.1 - 0.00092 19.0 35.6 6.2 7.4 0.1 10.8 12 0 0 12 12 12 2 Leucine rich repeat LRRNT PF01462.13 KFM09712.1 - 0.0014 18.0 3.9 0.0042 16.5 1.8 2.5 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain fn3 PF00041.16 KFM09712.1 - 0.004 17.2 0.0 0.0087 16.1 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain LRRCT PF01463.19 KFM09712.1 - 0.022 15.0 0.0 0.073 13.3 0.0 2.0 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain Herpes_gE PF02480.11 KFM09712.1 - 0.055 11.7 0.0 0.078 11.2 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E RRM_1 PF00076.17 KFM09714.1 - 8.1e-27 92.6 0.5 1.5e-14 53.3 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM09714.1 - 1.2e-17 63.5 0.5 2.2e-11 43.3 0.0 2.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM09714.1 - 9.4e-15 54.3 0.4 8.2e-07 28.9 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 KFM09714.1 - 4.9e-05 22.9 0.9 0.00097 18.7 0.0 2.6 2 1 1 3 3 3 1 Calcipressin DUF45 PF01863.12 KFM09714.1 - 0.043 13.6 0.7 0.1 12.3 0.4 1.6 1 1 1 2 2 2 0 Protein of unknown function DUF45 SH3_2 PF07653.12 KFM09715.1 - 8.8e-18 63.5 0.0 1.3e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KFM09715.1 - 6.3e-05 22.4 0.1 0.00012 21.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM09715.1 - 0.15 11.4 0.2 0.81 9.1 0.2 2.0 1 1 0 1 1 1 0 SH3 domain DUF3104 PF11302.3 KFM09715.1 - 0.15 11.4 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) Peptidase_S8 PF00082.17 KFM09716.1 - 2.4e-53 181.1 3.6 3.3e-53 180.6 2.5 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 KFM09716.1 - 4.7e-30 103.2 0.1 9.5e-30 102.2 0.1 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain Filament PF00038.16 KFM09717.1 - 3.6e-24 85.7 43.5 6.7e-21 75.0 13.8 2.4 2 0 0 2 2 2 2 Intermediate filament protein TPR_MLP1_2 PF07926.7 KFM09717.1 - 4e-14 52.4 0.0 0.013 15.2 7.9 4.9 4 2 0 4 4 4 2 TPR/MLP1/MLP2-like protein Lectin_N PF03954.9 KFM09717.1 - 0.24 10.8 4.1 0.21 10.9 0.4 2.5 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain Baculo_PEP_C PF04513.7 KFM09717.1 - 0.75 9.6 11.8 0.22 11.3 0.5 3.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.1 KFM09717.1 - 2.2 7.1 18.2 5.8 5.7 0.0 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4407) 7tm_1 PF00001.16 KFM09718.1 - 8e-48 162.8 23.8 1e-47 162.4 16.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM09718.1 - 1.1e-05 24.7 27.5 1.5e-05 24.3 19.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Lamprin PF06403.6 KFM09719.1 - 1.3e-05 24.9 16.5 0.0012 18.5 2.5 2.0 1 1 1 2 2 2 2 Lamprin Ninjurin PF04923.7 KFM09721.1 - 1.3e-36 124.4 3.8 1.5e-36 124.2 2.6 1.0 1 0 0 1 1 1 1 Ninjurin CARD PF00619.16 KFM09722.1 - 9.5e-08 31.7 0.1 1.7e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 Caspase recruitment domain NADH5_C PF06455.6 KFM09722.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 NADH dehydrogenase subunit 5 C-terminus Sushi PF00084.15 KFM09723.1 - 4.4e-07 30.1 0.4 7.7e-07 29.3 0.3 1.4 1 0 0 1 1 1 1 Sushi domain (SCR repeat) Shisa PF13908.1 KFM09723.1 - 0.0028 17.8 0.2 0.0031 17.7 0.2 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator IncA PF04156.9 KFM09723.1 - 0.024 14.2 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 IncA protein EphA2_TM PF14575.1 KFM09723.1 - 0.091 13.1 0.2 0.15 12.5 0.1 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RhoGEF PF00621.15 KFM09725.1 - 1.4e-47 161.8 0.5 1.4e-47 161.8 0.3 1.9 3 0 0 3 3 3 1 RhoGEF domain PH PF00169.24 KFM09725.1 - 1.3e-19 70.3 0.3 2.2e-11 43.8 0.0 2.6 2 0 0 2 2 2 2 PH domain FYVE PF01363.16 KFM09725.1 - 1.2e-14 53.8 14.7 9.9e-14 51.0 10.2 2.4 2 0 0 2 2 2 1 FYVE zinc finger PH_11 PF15413.1 KFM09725.1 - 0.0059 16.8 1.5 0.04 14.1 0.0 3.0 3 0 0 3 3 3 1 Pleckstrin homology domain PH_9 PF15410.1 KFM09725.1 - 0.029 14.5 2.0 5 7.2 0.1 3.2 3 0 0 3 3 3 0 Pleckstrin homology domain Mcp5_PH PF12814.2 KFM09725.1 - 0.032 14.1 0.2 0.29 11.0 0.1 2.3 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology FYVE_2 PF02318.11 KFM09725.1 - 8 6.3 24.3 0.088 12.7 9.8 2.7 3 0 0 3 3 3 0 FYVE-type zinc finger BicD PF09730.4 KFM09726.1 - 0 1103.9 78.6 7.1e-281 933.7 35.3 2.0 2 0 0 2 2 2 2 Microtubule-associated protein Bicaudal-D DUF869 PF05911.6 KFM09726.1 - 0.00042 18.7 76.7 0.0095 14.2 6.6 4.5 2 1 2 4 4 4 3 Plant protein of unknown function (DUF869) NPV_P10 PF05531.7 KFM09726.1 - 0.029 14.6 1.8 0.029 14.6 1.2 7.2 6 2 0 6 6 6 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 KFM09726.1 - 0.65 9.5 87.8 0.15 11.6 5.3 6.5 5 1 1 6 6 6 0 IncA protein ERM PF00769.14 KFM09726.1 - 1.6 8.2 86.5 0.51 9.8 5.1 5.0 4 1 1 5 5 5 0 Ezrin/radixin/moesin family APG6 PF04111.7 KFM09726.1 - 2.3 7.2 86.6 0.17 10.8 6.9 5.8 5 1 0 5 5 5 0 Autophagy protein Apg6 C1-set PF07654.10 KFM09727.1 - 8.8e-19 67.3 0.0 1.8e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_2 PF13895.1 KFM09727.1 - 0.00045 20.2 0.0 0.0012 18.9 0.0 1.7 2 0 0 2 2 2 1 Immunoglobulin domain C2-set_2 PF08205.7 KFM09727.1 - 0.0035 17.2 0.0 0.0055 16.5 0.0 1.4 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain I-set PF07679.11 KFM09727.1 - 0.011 15.5 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin I-set domain C1-set PF07654.10 KFM09728.1 - 3.1e-19 68.7 0.0 5.6e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_2 PF13895.1 KFM09728.1 - 3.8e-05 23.7 0.0 7.2e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain MHC_I PF00129.13 KFM09728.1 - 0.00036 19.9 0.0 0.00058 19.2 0.0 1.3 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C2-set_2 PF08205.7 KFM09728.1 - 0.00061 19.6 0.0 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.1 KFM09728.1 - 0.0013 19.1 0.1 0.003 18.0 0.0 1.6 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.11 KFM09728.1 - 0.0032 17.2 0.0 0.0058 16.4 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Marek_A PF02124.10 KFM09728.1 - 0.1 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Marek's disease glycoprotein A Syntaphilin PF15290.1 KFM09729.1 - 7e-122 406.6 17.6 1.2e-121 405.9 12.2 1.4 1 0 0 1 1 1 1 Golgi-localised syntaxin-1-binding clamp DUF812 PF05667.6 KFM09729.1 - 0.00073 18.1 7.6 0.0011 17.6 5.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) MAD PF05557.8 KFM09729.1 - 0.0034 15.5 19.8 0.0058 14.8 13.8 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein Exonuc_VII_L PF02601.10 KFM09729.1 - 0.0035 16.5 1.2 0.0047 16.1 0.8 1.3 1 0 0 1 1 1 1 Exonuclease VII, large subunit Spc7 PF08317.6 KFM09729.1 - 0.024 13.3 15.4 0.046 12.3 10.7 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_13 PF13166.1 KFM09729.1 - 0.051 12.0 10.5 0.08 11.4 7.3 1.2 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 KFM09729.1 - 0.053 13.1 13.9 0.1 12.2 9.7 1.4 1 0 0 1 1 1 0 IncA protein AAA_27 PF13514.1 KFM09729.1 - 0.057 11.1 10.6 0.081 10.5 7.4 1.1 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.3 KFM09729.1 - 0.064 10.5 13.6 0.09 10.0 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Sec8_exocyst PF04048.9 KFM09729.1 - 0.21 11.2 12.7 0.97 9.0 0.6 2.3 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain BTV_NS2 PF04514.7 KFM09729.1 - 0.37 9.6 8.4 0.68 8.7 5.8 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 GAS PF13851.1 KFM09729.1 - 0.5 9.5 20.9 1.4 8.0 14.4 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.7 KFM09729.1 - 0.51 10.1 3.0 1.5 8.6 2.1 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_MLP1_2 PF07926.7 KFM09729.1 - 0.66 9.7 19.1 16 5.2 13.3 2.3 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF641 PF04859.7 KFM09729.1 - 0.81 9.4 14.1 4 7.2 2.0 2.6 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Atg14 PF10186.4 KFM09729.1 - 0.82 8.5 14.9 1.5 7.7 10.4 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 GrpE PF01025.14 KFM09729.1 - 1.5 8.3 13.9 2.9 7.4 9.6 1.3 1 0 0 1 1 1 0 GrpE TBPIP PF07106.8 KFM09729.1 - 2.8 7.4 17.1 6.3 6.3 10.6 2.3 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF342 PF03961.8 KFM09729.1 - 3.3 6.0 13.0 4.8 5.4 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 KFM09729.1 - 7.9 5.4 16.5 14 4.5 11.4 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1682 PF07946.9 KFM09730.1 - 8 5.2 15.8 12 4.6 10.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) GDPD PF03009.12 KFM09731.1 - 1.2e-59 201.9 0.0 1.9e-59 201.2 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family CBM_20 PF00686.14 KFM09731.1 - 3e-09 36.3 0.0 9e-09 34.8 0.0 1.8 1 0 0 1 1 1 1 Starch binding domain PI-PLC-X PF00388.14 KFM09731.1 - 0.069 12.5 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain DUF4521 PF15021.1 KFM09732.1 - 4.3e-70 235.4 1.0 7.9e-70 234.6 0.7 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4521) Granin PF01271.12 KFM09733.1 - 2.5e-50 171.7 122.1 3.2e-50 171.4 84.7 1.1 1 0 0 1 1 1 1 Granin (chromogranin or secretogranin) Gcd10p PF04189.8 KFM09734.1 - 2.3e-75 253.5 0.2 2.3e-75 253.5 0.1 2.2 1 1 1 2 2 2 1 Gcd10p family INTS5_C PF14838.1 KFM09734.1 - 0.05 11.8 0.1 0.081 11.2 0.1 1.2 1 0 0 1 1 1 0 Integrator complex subunit 5 C-terminus Selenoprotein_S PF06936.6 KFM09734.1 - 3.4 7.1 8.2 6.8 6.1 5.7 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) MCM PF00493.18 KFM09735.1 - 1.9e-125 418.0 0.0 2.5e-125 417.6 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 KFM09735.1 - 2.9e-08 33.1 0.0 5.7e-05 22.3 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KFM09735.1 - 1.2e-07 31.5 0.0 3e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM_N PF14551.1 KFM09735.1 - 0.00032 21.1 1.6 0.0017 18.8 0.1 2.8 3 0 0 3 3 3 1 MCM N-terminal domain AAA_3 PF07726.6 KFM09735.1 - 0.00044 19.8 0.0 0.0012 18.4 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 KFM09735.1 - 0.00077 18.9 0.0 0.012 15.1 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA PF00004.24 KFM09735.1 - 0.0075 16.4 0.0 0.024 14.8 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFM09735.1 - 0.021 14.9 0.0 0.069 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KFM09735.1 - 0.032 13.9 0.0 1.3 8.7 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_16 PF13191.1 KFM09735.1 - 0.072 13.0 2.1 0.87 9.5 0.0 3.2 4 0 0 4 4 4 0 AAA ATPase domain CDP-OH_P_transf PF01066.16 KFM09736.1 - 9.2e-15 54.7 8.9 3.1e-14 53.1 6.1 2.0 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase HCaRG PF07258.9 KFM09737.1 - 1.9e-39 135.0 5.0 2e-39 134.9 3.5 1.0 1 0 0 1 1 1 1 HCaRG protein PRP38 PF03371.10 KFM09737.1 - 0.091 12.3 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 PRP38 family DUF2624 PF11116.3 KFM09737.1 - 0.15 12.5 0.8 3.7 8.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2624) Galactosyl_T PF01762.16 KFM09738.1 - 1.4e-42 145.4 0.0 2.5e-42 144.7 0.0 1.4 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.11 KFM09738.1 - 0.0016 17.7 0.0 0.0026 17.0 0.0 1.2 1 0 0 1 1 1 1 Fringe-like DUF604 PF04646.7 KFM09738.1 - 0.0073 15.5 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF604 EGF_CA PF07645.10 KFM09739.1 - 1.1e-08 34.8 7.0 2e-08 34.0 4.9 1.4 1 0 0 1 1 1 1 Calcium-binding EGF domain EGF_3 PF12947.2 KFM09739.1 - 0.00014 21.7 5.9 0.00024 21.0 4.1 1.4 1 0 0 1 1 1 1 EGF domain DUF3844 PF12955.2 KFM09739.1 - 0.0012 18.9 0.4 0.0018 18.3 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_MSP1_1 PF12946.2 KFM09739.1 - 0.0033 17.1 2.8 0.0056 16.4 1.9 1.5 1 0 0 1 1 1 1 MSP1 EGF domain 1 EGF PF00008.22 KFM09739.1 - 0.028 14.3 4.9 0.078 12.9 2.9 2.1 2 0 0 2 2 2 0 EGF-like domain FXa_inhibition PF14670.1 KFM09739.1 - 0.061 13.4 3.2 0.16 12.1 2.3 1.7 1 1 0 1 1 1 0 Coagulation Factor Xa inhibitory site Transmemb_17 PF09799.4 KFM09740.1 - 2.3e-32 111.5 14.7 3.7e-32 110.9 10.2 1.3 1 0 0 1 1 1 1 Predicted membrane protein DUF3366 PF11846.3 KFM09740.1 - 0.82 9.5 5.8 0.31 10.8 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3366) DUF3043 PF11241.3 KFM09740.1 - 3.4 7.2 11.6 0.94 9.0 1.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3043) TF_Otx PF03529.8 KFM09741.1 - 7e-31 106.2 17.6 7e-31 106.2 12.2 2.4 2 0 0 2 2 2 1 Otx1 transcription factor Homeobox PF00046.24 KFM09741.1 - 0.18 11.4 1.3 0.27 10.8 0.9 1.3 1 0 0 1 1 1 0 Homeobox domain DUF566 PF04484.7 KFM09741.1 - 3.2 7.1 10.5 3.4 7.1 7.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF3312 PF11768.3 KFM09743.1 - 2.8e-227 755.2 0.1 3.2e-227 755.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) Ldh_1_C PF02866.13 KFM09744.1 - 5.3e-50 169.5 0.0 1.5e-49 168.1 0.0 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 KFM09744.1 - 7.7e-36 123.0 0.4 1.4e-35 122.1 0.1 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain UDPGP PF01704.13 KFM09745.1 - 6.8e-192 637.5 0.6 1e-191 637.0 0.4 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4301 PF14134.1 KFM09745.1 - 0.017 13.6 0.2 1.1 7.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4301) Vps54 PF07928.7 KFM09746.1 - 6.4e-60 201.1 4.5 7.2e-60 201.0 0.7 2.9 3 0 0 3 3 3 1 Vps54-like protein DUF2450 PF10475.4 KFM09746.1 - 5.7e-09 35.2 7.6 5.7e-09 35.2 5.3 2.8 3 0 0 3 3 3 1 Protein of unknown function N-terminal domain (DUF2450) Pellino PF04710.9 KFM09747.1 - 2.9e-238 790.4 0.1 3.2e-238 790.2 0.1 1.0 1 0 0 1 1 1 1 Pellino zf-C3HC4_3 PF13920.1 KFM09747.1 - 0.00078 19.0 6.2 0.5 10.0 0.2 3.0 2 2 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM09747.1 - 0.0012 18.7 6.6 0.028 14.4 0.0 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFM09747.1 - 0.0058 16.3 0.8 6.6 6.5 0.0 3.3 2 0 0 2 2 2 2 RING-type zinc-finger zf-RING_2 PF13639.1 KFM09747.1 - 0.26 11.1 12.5 0.9 9.4 1.3 3.2 3 1 0 3 3 3 0 Ring finger domain Prok-RING_4 PF14447.1 KFM09747.1 - 3.2 7.3 10.9 5.8 6.5 0.1 3.6 3 1 0 3 3 3 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.2 KFM09747.1 - 4.5 7.4 7.1 0.82 9.8 0.2 2.6 2 0 0 2 2 2 0 RING-H2 zinc finger zf-RING_5 PF14634.1 KFM09747.1 - 6.1 6.6 10.2 0.57 9.9 0.1 3.4 2 2 0 2 2 2 0 zinc-RING finger domain DUF2189 PF09955.4 KFM09749.1 - 0.052 13.4 4.7 0.068 13.1 3.3 1.1 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2189) TMEM154 PF15102.1 KFM09750.1 - 0.0013 18.4 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 TMEM154 protein family Brr6_like_C_C PF10104.4 KFM09750.1 - 0.0022 17.4 0.2 0.0035 16.8 0.2 1.3 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain CD34_antigen PF06365.7 KFM09750.1 - 0.0043 16.7 0.0 0.0052 16.4 0.0 1.2 1 0 0 1 1 1 1 CD34/Podocalyxin family 7tm_1 PF00001.16 KFM09750.1 - 0.0065 15.6 0.0 0.0065 15.6 0.0 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF1049 PF06305.6 KFM09750.1 - 0.01 15.3 0.1 0.018 14.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF3328 PF11807.3 KFM09750.1 - 0.013 15.2 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) RELT PF12606.3 KFM09750.1 - 0.02 14.0 0.6 0.03 13.4 0.4 1.2 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 PIRT PF15099.1 KFM09750.1 - 0.02 14.0 0.3 0.029 13.5 0.2 1.2 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family 7TM_GPCR_Srv PF10323.4 KFM09750.1 - 0.022 13.8 0.5 0.028 13.5 0.4 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv EphA2_TM PF14575.1 KFM09750.1 - 0.025 14.9 0.0 0.039 14.3 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3609 PF12259.3 KFM09750.1 - 0.03 12.9 0.0 0.037 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) Potyvirid-P3 PF13608.1 KFM09750.1 - 0.039 13.0 0.1 0.046 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein SieB PF14163.1 KFM09750.1 - 0.057 12.9 0.2 0.079 12.5 0.2 1.1 1 0 0 1 1 1 0 Superinfection exclusion protein B SID-1_RNA_chan PF13965.1 KFM09750.1 - 0.08 11.0 0.0 0.085 11.0 0.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Mem_trans PF03547.13 KFM09750.1 - 0.08 11.2 0.0 0.087 11.1 0.0 1.1 1 0 0 1 1 1 0 Membrane transport protein GRP PF07172.6 KFM09750.1 - 0.08 13.4 0.0 0.092 13.2 0.0 1.1 1 0 0 1 1 1 0 Glycine rich protein family Ctr PF04145.10 KFM09750.1 - 0.085 12.8 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Ctr copper transporter family Amnionless PF14828.1 KFM09750.1 - 0.094 11.1 0.0 0.094 11.1 0.0 1.1 1 0 0 1 1 1 0 Amnionless OSTbeta PF15048.1 KFM09750.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DUF3357 PF11837.3 KFM09750.1 - 0.13 12.1 0.2 0.24 11.2 0.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) DUF3404 PF11884.3 KFM09750.1 - 0.13 11.1 0.4 0.22 10.3 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3404) OAD_gamma PF04277.8 KFM09750.1 - 0.15 12.4 0.3 0.3 11.5 0.0 1.5 2 0 0 2 2 1 0 Oxaloacetate decarboxylase, gamma chain Yae1_N PF09811.4 KFM09751.1 - 1.3e-12 47.0 36.3 0.0066 15.9 6.8 3.8 1 1 1 2 2 2 2 Essential protein Yae1, N terminal DEAD PF00270.24 KFM09752.1 - 4.5e-45 153.1 0.1 1.5e-44 151.4 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KFM09752.1 - 5.2e-22 77.1 0.3 1.1e-21 76.0 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KFM09752.1 - 4.6e-21 74.4 0.0 1.1e-20 73.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KFM09752.1 - 0.047 13.4 0.2 0.38 10.5 0.0 2.5 3 0 0 3 3 3 0 Part of AAA domain Fer2 PF00111.22 KFM09753.1 - 4.8e-08 32.6 0.2 6.4e-08 32.2 0.1 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain zf-CHY PF05495.7 KFM09753.1 - 0.035 14.2 0.6 0.093 12.9 0.5 1.6 1 1 0 1 1 1 0 CHY zinc finger ERM PF00769.14 KFM09754.1 - 8.6e-83 277.6 50.6 8.6e-83 277.6 35.0 2.6 2 1 1 3 3 3 1 Ezrin/radixin/moesin family FERM_C PF09380.5 KFM09754.1 - 2.5e-33 114.1 0.0 7.1e-33 112.6 0.0 1.9 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.13 KFM09754.1 - 3.6e-26 91.7 1.8 3.6e-26 91.7 1.2 3.6 2 1 0 2 2 2 1 FERM central domain FERM_N PF09379.5 KFM09754.1 - 2.8e-19 68.9 0.3 2.8e-19 68.9 0.2 2.9 3 0 0 3 3 3 1 FERM N-terminal domain RNase_Zc3h12a PF11977.3 KFM09755.1 - 1.4e-64 216.6 0.0 1.9e-64 216.1 0.0 1.2 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain Omega-toxin PF06357.6 KFM09755.1 - 0.0094 15.5 4.8 0.018 14.6 3.3 1.3 1 0 0 1 1 1 1 Omega-atracotoxin RNase_Zc3h12a_2 PF14626.1 KFM09755.1 - 0.019 14.8 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain UPF0146 PF03686.8 KFM09755.1 - 0.072 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) zf-CCCH_2 PF14608.1 KFM09755.1 - 0.66 10.0 10.0 1.1 9.3 6.9 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type EGF PF00008.22 KFM09756.1 - 0.00067 19.5 0.6 0.00067 19.5 0.4 2.1 2 1 0 2 2 2 1 EGF-like domain hEGF PF12661.2 KFM09756.1 - 0.00096 19.0 1.5 0.00096 19.0 1.0 3.0 3 1 0 3 3 3 1 Human growth factor-like EGF EGF_2 PF07974.8 KFM09756.1 - 0.0011 19.0 1.5 0.0011 19.0 1.0 2.3 2 1 0 2 2 2 1 EGF-like domain Laminin_EGF PF00053.19 KFM09756.1 - 0.015 15.2 2.9 0.015 15.2 2.0 1.9 2 1 0 2 2 2 0 Laminin EGF-like (Domains III and V) cEGF PF12662.2 KFM09756.1 - 3.3 7.4 6.4 0.41 10.3 0.8 2.2 2 0 0 2 2 2 0 Complement Clr-like EGF-like zinc_ribbon_6 PF14599.1 KFM09758.1 - 4.7e-31 106.3 2.1 4.7e-31 106.3 1.5 3.8 3 1 1 4 4 4 1 Zinc-ribbon zf-RING_2 PF13639.1 KFM09758.1 - 7.6e-11 41.6 6.5 7.6e-11 41.6 4.5 3.8 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFM09758.1 - 3.8e-09 36.4 5.7 3.8e-09 36.4 4.0 4.7 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM09758.1 - 1.4e-07 31.0 4.5 1.4e-07 31.0 3.1 4.4 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM09758.1 - 5.7e-07 29.0 5.9 5.7e-07 29.0 4.1 5.0 2 2 2 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFM09758.1 - 8.3e-07 28.6 1.7 3.7e-06 26.5 1.2 2.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 KFM09758.1 - 1e-06 28.3 5.4 1e-06 28.3 3.7 5.6 2 2 2 4 4 4 1 zinc-RING finger domain zf-RING_4 PF14570.1 KFM09758.1 - 0.00013 21.4 3.0 0.00013 21.4 2.1 4.5 4 2 1 5 5 5 1 RING/Ubox like zinc-binding domain zf-UDP PF14569.1 KFM09758.1 - 0.015 14.9 0.6 0.015 14.9 0.4 3.0 3 2 0 3 3 3 0 Zinc-binding RING-finger Pkinase PF00069.20 KFM09759.1 - 6.1e-75 251.7 0.0 8.3e-75 251.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM09759.1 - 1e-40 139.4 0.0 3.8e-40 137.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM09759.1 - 4.3e-08 32.4 0.6 1.7e-06 27.2 0.0 2.7 2 1 1 3 3 3 1 Kinase-like Kdo PF06293.9 KFM09759.1 - 0.0026 16.8 0.1 0.0065 15.5 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFM09759.1 - 0.032 13.9 0.0 0.17 11.5 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family LPP20 PF02169.11 KFM09760.1 - 0.027 14.5 2.5 0.064 13.3 1.8 1.6 1 0 0 1 1 1 0 LPP20 lipoprotein Herpes_UL87 PF03043.9 KFM09760.1 - 0.056 11.8 0.4 0.061 11.7 0.3 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family PA26 PF04636.8 KFM09760.1 - 9.2 4.8 12.2 0.78 8.3 3.8 1.9 1 1 1 2 2 2 0 PA26 p53-induced protein (sestrin) FHA PF00498.21 KFM09761.1 - 0.00032 20.7 0.0 0.00045 20.2 0.0 1.2 1 0 0 1 1 1 1 FHA domain Alpha_kinase PF02816.13 KFM09762.1 - 9.4e-45 152.6 2.1 1.5e-44 151.8 1.5 1.4 1 0 0 1 1 1 1 Alpha-kinase family AAA_12 PF13087.1 KFM09763.1 - 6.6e-52 175.8 0.2 2.4e-51 173.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KFM09763.1 - 3.2e-33 115.2 0.1 7.1e-33 114.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain zf-GRF PF06839.7 KFM09763.1 - 1.6e-14 53.4 0.3 3.9e-14 52.2 0.2 1.7 1 0 0 1 1 1 1 GRF zinc finger Viral_helicase1 PF01443.13 KFM09763.1 - 2.1e-08 34.0 0.1 0.017 14.6 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 KFM09763.1 - 0.00066 19.3 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KFM09763.1 - 0.00093 18.8 0.0 0.051 13.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.1 KFM09763.1 - 0.0095 16.0 0.0 0.023 14.8 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Toxin_61 PF15538.1 KFM09763.1 - 0.055 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative toxin 61 CCT_2 PF09425.5 KFM09763.1 - 0.4 10.2 2.2 1 8.9 1.5 1.6 1 0 0 1 1 1 0 Divergent CCT motif DUF2439 PF10382.4 KFM09764.1 - 5.1e-18 65.0 0.3 1.4e-17 63.6 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) RRM_3 PF08777.6 KFM09765.1 - 2e-28 98.3 0.2 2e-28 98.3 0.1 3.9 4 1 0 4 4 4 2 RNA binding motif La PF05383.12 KFM09765.1 - 3.4e-24 84.3 0.1 7.3e-24 83.3 0.0 1.6 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 KFM09765.1 - 5.5e-19 67.5 0.1 1.1e-15 56.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM09765.1 - 1.7e-17 63.1 0.0 6.4e-13 48.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM09765.1 - 1.6e-13 50.3 0.1 2.9e-09 36.6 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ank PF00023.25 KFM09766.1 - 7.3e-189 603.0 59.9 8.6e-10 37.9 0.0 22.8 23 0 0 23 23 23 21 Ankyrin repeat Ank_2 PF12796.2 KFM09766.1 - 1e-162 528.9 47.2 1.1e-22 80.1 0.2 11.1 3 3 8 11 11 11 11 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KFM09766.1 - 6.9e-127 400.4 36.2 2e-06 27.4 0.0 23.0 23 0 0 23 23 23 21 Ankyrin repeat Ank_4 PF13637.1 KFM09766.1 - 1e-123 401.7 46.9 1.4e-12 47.7 0.0 14.9 4 3 11 17 17 17 17 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM09766.1 - 1.4e-117 381.0 49.2 3.4e-11 42.9 0.6 18.9 3 3 18 21 21 21 20 Ankyrin repeats (many copies) ZU5 PF00791.15 KFM09766.1 - 6.3e-44 147.8 1.0 2.6e-39 133.0 0.0 2.9 2 0 0 2 2 2 2 ZU5 domain Death PF00531.17 KFM09766.1 - 9.4e-20 70.1 1.4 2.1e-19 69.0 0.6 2.0 2 0 0 2 2 2 1 Death domain Shigella_OspC PF06128.6 KFM09766.1 - 0.003 17.0 3.7 4.1 6.8 0.1 5.0 5 0 0 5 5 5 2 Shigella flexneri OspC protein Sulfatase PF00884.18 KFM09768.1 - 8.9e-45 153.1 0.0 1.3e-44 152.6 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 KFM09768.1 - 3.6e-05 24.0 0.0 9.7e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase UDPGT PF00201.13 KFM09769.1 - 3.3e-120 402.0 0.0 4.1e-120 401.6 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 KFM09769.1 - 1e-05 25.2 0.0 1.8e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Imm20 PF15568.1 KFM09769.1 - 0.0027 17.5 0.1 0.0052 16.6 0.1 1.4 1 0 0 1 1 1 1 Immunity protein 20 DUF2838 PF10998.3 KFM09769.1 - 0.051 13.4 1.1 0.13 12.1 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2838) PMBR PF09373.5 KFM09769.1 - 1.4 8.9 3.7 32 4.6 0.0 3.8 3 0 0 3 3 3 0 Pseudomurein-binding repeat HSNSD PF12062.3 KFM09770.1 - 1.5e-256 851.4 0.0 2.5e-256 850.7 0.0 1.3 1 0 0 1 1 1 1 heparan sulfate-N-deacetylase Sulfotransfer_1 PF00685.22 KFM09770.1 - 3.9e-42 144.3 0.0 7.3e-42 143.4 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 KFM09770.1 - 0.002 19.0 0.1 0.0097 16.8 0.1 2.2 1 1 0 1 1 1 1 Sulfotransferase family Sulfatase PF00884.18 KFM09771.1 - 8.4e-49 166.4 1.4 1.2e-48 165.9 0.9 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KFM09771.1 - 3.2e-05 23.4 2.7 8.6e-05 22.0 1.9 1.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KFM09771.1 - 0.00033 19.2 0.0 0.00069 18.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.13 KFM09771.1 - 0.013 14.9 0.0 0.046 13.1 0.0 1.9 2 1 0 2 2 2 0 Metalloenzyme superfamily Ehrlichia_rpt PF09528.5 KFM09771.1 - 0.23 9.5 0.1 0.34 8.9 0.0 1.1 1 0 0 1 1 1 0 Ehrlichia tandem repeat (Ehrlichia_rpt) Sec7 PF01369.15 KFM09772.1 - 1.3e-68 230.4 2.6 1.8e-68 229.9 0.7 2.2 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.2 KFM09772.1 - 3.9e-57 192.3 2.6 1.9e-56 190.1 1.8 2.4 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KFM09772.1 - 1.5e-30 104.5 0.1 1.5e-30 104.5 0.1 5.2 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) CAS_CSE1 PF03378.10 KFM09773.1 - 6.5e-198 657.3 6.0 4.4e-197 654.6 2.9 2.2 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 KFM09773.1 - 8.4e-168 557.6 5.4 1.7e-167 556.6 3.7 1.6 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 KFM09773.1 - 8.5e-12 44.8 0.0 4.8e-11 42.4 0.0 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KFM09773.1 - 0.00057 19.8 6.5 0.0034 17.2 0.0 4.2 2 2 2 4 4 4 1 Exportin 1-like protein PUF PF00806.14 KFM09773.1 - 0.041 13.3 0.0 1 8.9 0.0 3.1 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat HEAT_2 PF13646.1 KFM09773.1 - 0.13 12.5 0.2 37 4.7 0.0 3.5 2 1 1 3 3 3 0 HEAT repeats Arm PF00514.18 KFM09773.1 - 0.37 10.7 3.5 41 4.1 0.1 4.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat dsrm PF00035.20 KFM09774.1 - 7.5e-51 170.5 3.5 1.8e-12 47.6 0.0 5.1 5 0 0 5 5 5 4 Double-stranded RNA binding motif DND1_DSRM PF14709.1 KFM09774.1 - 1.9e-09 37.6 2.1 0.0048 17.1 0.0 5.1 5 1 0 5 5 5 3 double strand RNA binding domain from DEAD END PROTEIN 1 LPP20 PF02169.11 KFM09774.1 - 0.029 14.4 0.1 7.7 6.6 0.0 3.4 3 0 0 3 3 3 0 LPP20 lipoprotein Guanylin PF02058.10 KFM09774.1 - 0.33 11.0 2.2 6.9 6.8 0.3 3.0 2 0 0 2 2 2 0 Guanylin precursor Glyco_transf_7N PF13733.1 KFM09775.1 - 2.5e-45 153.1 0.0 3.7e-45 152.6 0.0 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.9 KFM09775.1 - 2.4e-28 97.4 0.5 4.1e-28 96.6 0.3 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFM09775.1 - 1.6e-06 27.4 0.2 0.00063 18.9 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Na_H_Exchanger PF00999.16 KFM09776.1 - 1.8e-59 201.2 39.2 2.3e-59 200.8 27.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3995 PF13160.1 KFM09776.1 - 3.3 7.7 10.3 0.83 9.7 0.2 3.6 4 2 0 4 4 4 0 Protein of unknown function (DUF3995) Homeobox PF00046.24 KFM09777.1 - 5.3e-24 83.6 6.2 1.2e-23 82.4 4.3 1.6 1 0 0 1 1 1 1 Homeobox domain OAR PF03826.12 KFM09777.1 - 6.2e-10 38.2 0.6 1.6e-09 36.9 0.4 1.7 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.6 KFM09777.1 - 0.00037 20.1 0.1 0.00098 18.7 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain Staygreen PF12638.2 KFM09777.1 - 0.044 13.3 0.0 0.075 12.5 0.0 1.4 1 0 0 1 1 1 0 Staygreen protein IQ PF00612.22 KFM09778.1 - 6.2e-06 25.3 0.1 1.8e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif ERbeta_N PF12497.3 KFM09778.1 - 0.015 15.1 0.5 0.026 14.3 0.3 1.3 1 0 0 1 1 1 0 Estrogen receptor beta LRR_4 PF12799.2 KFM09779.1 - 4.1e-24 83.7 47.6 6.6e-07 28.8 0.5 7.5 3 2 5 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM09779.1 - 1.1e-19 69.9 42.9 3.6e-08 33.0 2.5 6.1 3 2 2 5 5 5 5 Leucine rich repeat LRR_1 PF00560.28 KFM09779.1 - 3.4e-06 26.3 48.1 2.2 8.6 0.5 11.3 9 2 2 11 11 11 4 Leucine Rich Repeat IQ PF00612.22 KFM09779.1 - 0.00051 19.4 0.2 0.0013 18.2 0.2 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif LRR_7 PF13504.1 KFM09779.1 - 0.56 10.6 42.4 4.5 7.9 0.1 10.8 11 1 0 11 11 11 0 Leucine rich repeat LRR_6 PF13516.1 KFM09779.1 - 2.8 8.2 43.6 1.1 9.5 0.1 10.2 8 2 3 11 11 11 0 Leucine Rich repeat SNF PF00209.13 KFM09780.1 - 7.3e-226 750.6 30.9 8.9e-226 750.3 21.4 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Peptidase_M50 PF02163.17 KFM09780.1 - 0.054 12.4 0.0 0.65 8.9 0.0 2.4 1 1 0 1 1 1 0 Peptidase family M50 Xpo1 PF08389.7 KFM09782.1 - 4.1e-25 88.4 0.5 6.5e-25 87.7 0.3 1.3 1 0 0 1 1 1 1 Exportin 1-like protein IBN_N PF03810.14 KFM09782.1 - 0.0034 17.2 0.3 0.018 14.9 0.1 2.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain Tetraspannin PF00335.15 KFM09783.1 - 1.7e-34 119.0 6.9 2.1e-34 118.7 4.8 1.1 1 0 0 1 1 1 1 Tetraspanin family Frizzled PF01534.12 KFM09784.1 - 5.9e-120 399.9 13.6 6.9e-120 399.7 9.4 1.0 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Dicty_CAR PF05462.6 KFM09784.1 - 2e-05 23.6 2.9 2e-05 23.6 2.0 1.9 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor AdoHcyase PF05221.12 KFM09785.1 - 1.4e-119 397.9 0.0 1.6e-119 397.7 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 KFM09785.1 - 1.5e-81 271.9 2.1 2.3e-81 271.3 1.4 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 KFM09785.1 - 1.2e-09 37.5 0.1 2.8e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 KFM09785.1 - 9.2e-05 21.5 0.9 0.00036 19.6 0.6 1.8 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain IlvN PF07991.7 KFM09785.1 - 0.0003 20.1 0.0 0.00064 19.1 0.0 1.6 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain Shikimate_DH PF01488.15 KFM09785.1 - 0.0012 18.9 0.7 0.0061 16.6 0.5 2.0 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 KFM09785.1 - 0.0016 18.6 0.4 0.0041 17.3 0.2 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding TrkA_N PF02254.13 KFM09785.1 - 0.0018 18.2 0.2 0.0075 16.2 0.1 2.1 1 1 0 1 1 1 1 TrkA-N domain Malic_M PF03949.10 KFM09785.1 - 0.0025 17.4 1.5 0.021 14.3 0.0 2.2 1 1 0 2 2 2 1 Malic enzyme, NAD binding domain AlaDh_PNT_C PF01262.16 KFM09785.1 - 0.02 14.4 1.6 0.31 10.6 0.1 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.16 KFM09785.1 - 0.029 13.9 2.7 0.92 9.0 0.2 2.3 1 1 1 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ThiF PF00899.16 KFM09785.1 - 2.8 7.7 5.1 26 4.6 0.1 2.4 1 1 1 2 2 2 0 ThiF family DUF1639 PF07797.9 KFM09787.1 - 0.0063 15.8 1.0 0.0063 15.8 0.7 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1639) Nrf1_DNA-bind PF10491.4 KFM09788.1 - 3.4e-129 428.2 0.3 5.4e-129 427.6 0.2 1.3 1 0 0 1 1 1 1 NLS-binding and DNA-binding and dimerisation domains of Nrf1 Nrf1_activ_bdg PF10492.4 KFM09788.1 - 7.8e-07 29.4 5.4 7.8e-07 29.4 3.8 6.2 3 2 3 6 6 6 1 Nrf1 activator activation site binding domain RNF111_N PF15303.1 KFM09788.1 - 0.021 14.3 0.6 0.056 12.9 0.4 1.7 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus DUF3459 PF11941.3 KFM09788.1 - 0.024 14.7 1.2 0.095 12.8 0.8 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) UQ_con PF00179.21 KFM09789.1 - 1.1e-36 125.3 0.0 1.4e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-C3HC PF07967.8 KFM09790.1 - 2.7e-33 114.5 1.4 2.7e-33 114.5 1.0 3.3 3 1 0 3 3 3 2 C3HC zinc finger-like Rsm1 PF08600.5 KFM09790.1 - 5.5e-12 45.3 14.0 5.5e-08 32.5 1.5 3.4 3 0 0 3 3 3 2 Rsm1-like DUF1220 PF06758.8 KFM09790.1 - 0.051 13.3 0.3 0.17 11.7 0.2 1.9 1 0 0 1 1 1 0 Repeat of unknown function (DUF1220) Kelch_6 PF13964.1 KFM09791.1 - 7.3e-41 136.7 6.8 2.5e-07 30.5 0.0 6.2 5 1 1 6 6 6 6 Kelch motif Kelch_4 PF13418.1 KFM09791.1 - 1.3e-40 136.8 4.1 1.1e-09 37.8 0.0 6.4 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.20 KFM09791.1 - 7.8e-40 134.1 14.0 1.1e-08 34.4 0.0 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.1 KFM09791.1 - 6e-33 112.2 12.6 8.7e-07 28.9 0.0 7.2 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.1 KFM09791.1 - 2.3e-31 107.1 7.8 1e-05 25.3 0.0 6.4 6 1 0 6 6 6 6 Kelch motif Kelch_2 PF07646.10 KFM09791.1 - 2.2e-27 93.7 12.5 6.2e-06 25.7 0.1 6.8 5 2 1 6 6 6 6 Kelch motif RAG2 PF03089.9 KFM09791.1 - 0.064 11.9 0.0 0.58 8.8 0.0 2.3 2 0 0 2 2 2 0 Recombination activating protein 2 Na_Ca_ex PF01699.19 KFM09792.1 - 7.8e-20 70.9 19.2 8.4e-12 44.8 7.4 3.6 5 0 0 5 5 5 2 Sodium/calcium exchanger protein DUF307 PF03733.8 KFM09792.1 - 6.2e-18 64.9 13.9 6.2e-18 64.9 9.6 4.0 3 0 0 3 3 3 1 Domain of unknown function (DUF307) CytochromB561_N PF09786.4 KFM09793.1 - 3.5e-202 672.9 2.9 4.5e-202 672.6 2.0 1.0 1 0 0 1 1 1 1 Cytochrome B561, N terminal NPCC PF08058.6 KFM09793.1 - 0.0086 15.9 0.0 0.026 14.3 0.0 1.8 1 1 0 1 1 1 1 Nuclear pore complex component CoA_binding_3 PF13727.1 KFM09793.1 - 0.17 11.6 0.8 0.36 10.6 0.5 1.5 1 0 0 1 1 1 0 CoA-binding domain DUF4636 PF15468.1 KFM09794.1 - 4.2e-11 42.7 0.7 5.3e-11 42.4 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4636) Peptidase_M14 PF00246.19 KFM09795.1 - 1.3e-85 287.4 0.0 1.6e-85 287.1 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 KFM09795.1 - 3.8e-23 80.9 0.2 6.9e-23 80.1 0.1 1.4 1 0 0 1 1 1 1 Carboxypeptidase activation peptide Phage_min_tail PF05939.8 KFM09795.1 - 0.014 15.3 0.0 1.4 8.9 0.0 2.6 2 0 0 2 2 2 0 Phage minor tail protein Peptidase_M14 PF00246.19 KFM09796.1 - 8.8e-83 278.1 0.2 1.1e-82 277.8 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 KFM09796.1 - 2.2e-24 84.9 0.1 5e-24 83.7 0.1 1.6 1 0 0 1 1 1 1 Carboxypeptidase activation peptide HCBP_related PF06594.6 KFM09796.1 - 0.12 12.0 0.6 0.33 10.6 0.1 1.9 2 0 0 2 2 2 0 Haemolysin-type calcium binding protein related domain Peptidase_M14 PF00246.19 KFM09797.1 - 3.7e-82 276.0 0.0 4.4e-82 275.8 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 KFM09797.1 - 1.9e-22 78.6 0.2 4.3e-22 77.5 0.1 1.6 1 0 0 1 1 1 1 Carboxypeptidase activation peptide Phage_min_tail PF05939.8 KFM09797.1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Phage minor tail protein Rhodanese PF00581.15 KFM09798.1 - 2.2e-12 47.3 0.0 5.3e-12 46.0 0.0 1.7 2 0 0 2 2 2 1 Rhodanese-like domain Abhydrolase_6 PF12697.2 KFM09799.1 - 3e-22 79.6 0.0 3.4e-22 79.4 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFM09799.1 - 7.5e-07 28.9 0.0 1.3e-06 28.1 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFM09799.1 - 6.3e-05 22.7 0.0 0.00018 21.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.7 KFM09799.1 - 0.004 16.0 0.0 0.0055 15.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Adaptin_N PF01602.15 KFM09800.1 - 1.1e-134 449.6 9.7 1.3e-134 449.3 6.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 KFM09800.1 - 1.9e-62 209.5 0.1 4.7e-62 208.2 0.1 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 KFM09800.1 - 1.7e-14 53.8 0.7 0.00075 19.7 0.0 6.3 1 1 5 6 6 6 3 HEAT repeats HEAT_EZ PF13513.1 KFM09800.1 - 1.2e-09 38.3 0.6 0.00068 20.0 0.2 4.2 4 0 0 4 4 4 2 HEAT-like repeat HEAT PF02985.17 KFM09800.1 - 4.5e-07 29.4 9.8 0.28 11.3 0.1 7.2 8 0 0 8 8 8 3 HEAT repeat Cnd1 PF12717.2 KFM09800.1 - 5e-06 26.4 7.3 0.5 10.1 0.2 4.4 4 0 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 UNC45-central PF11701.3 KFM09800.1 - 0.015 14.9 1.0 1.9 8.0 0.6 3.2 1 1 1 2 2 2 0 Myosin-binding striated muscle assembly central HEAT_PBS PF03130.11 KFM09800.1 - 0.037 14.4 1.7 2.4 8.8 0.1 4.2 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat UvrD-helicase PF00580.16 KFM09801.1 - 3.7e-13 49.4 1.9 2.1e-08 33.8 0.0 2.9 2 1 0 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 KFM09801.1 - 4.3e-12 46.1 0.0 9.1e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain F-box-like PF12937.2 KFM09801.1 - 3.3e-11 42.7 1.2 1.2e-10 40.9 0.8 2.0 2 0 0 2 2 2 1 F-box-like UvrD_C_2 PF13538.1 KFM09801.1 - 1.7e-09 37.7 0.3 1.7e-08 34.5 0.1 2.6 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 KFM09801.1 - 4.5e-09 36.1 0.1 0.0095 15.4 0.0 4.0 3 1 0 3 3 3 3 Viral (Superfamily 1) RNA helicase F-box PF00646.28 KFM09801.1 - 9.1e-09 34.7 0.6 3.3e-08 32.9 0.4 2.0 1 0 0 1 1 1 1 F-box domain AAA_12 PF13087.1 KFM09801.1 - 1.9e-06 27.4 1.5 0.0017 17.8 0.1 3.0 3 1 0 3 3 3 2 AAA domain AAA_30 PF13604.1 KFM09801.1 - 1.9e-06 27.6 0.0 0.07 12.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KFM09801.1 - 0.0011 19.1 0.0 0.97 9.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KFM09801.1 - 0.0015 18.2 0.0 0.0041 16.8 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain PhoH PF02562.11 KFM09801.1 - 0.0028 16.9 0.1 0.79 8.9 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_11 PF13086.1 KFM09801.1 - 0.049 13.2 2.2 1.4 8.4 1.6 2.4 1 1 0 1 1 1 0 AAA domain Ank_2 PF12796.2 KFM09802.1 - 4.8e-64 212.7 14.2 6e-22 77.7 0.3 4.5 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KFM09802.1 - 8.4e-61 198.9 14.5 5.3e-09 35.4 0.0 9.2 9 0 0 9 9 9 9 Ankyrin repeat Ank_4 PF13637.1 KFM09802.1 - 1.4e-58 194.3 17.9 1e-12 48.2 0.0 6.4 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM09802.1 - 2.3e-49 160.4 6.9 8.8e-06 25.4 0.0 9.3 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.1 KFM09802.1 - 2.1e-48 161.2 13.9 2.1e-10 40.4 0.1 8.5 1 1 8 9 9 9 9 Ankyrin repeats (many copies) DUF249 PF03158.8 KFM09802.1 - 0.048 13.1 0.0 8.5 5.8 0.0 2.8 2 1 1 3 3 3 0 Multigene family 530 protein GDI PF00996.13 KFM09803.1 - 4.9e-215 713.8 0.1 5.8e-215 713.6 0.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Amino_oxidase PF01593.19 KFM09803.1 - 0.18 10.8 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Ank PF00023.25 KFM09806.1 - 8.7e-51 167.3 13.4 2.2e-09 36.6 0.0 7.0 6 1 0 6 6 6 6 Ankyrin repeat Ank_2 PF12796.2 KFM09806.1 - 8.1e-45 151.0 8.9 2.6e-21 75.7 0.1 3.3 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFM09806.1 - 2.7e-32 110.5 4.2 2e-08 34.4 0.0 4.7 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM09806.1 - 2e-29 98.7 6.2 1.9e-05 24.4 0.1 6.7 6 1 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.1 KFM09806.1 - 2.5e-27 94.2 9.8 5.6e-07 29.5 0.1 5.8 4 1 3 7 7 7 5 Ankyrin repeats (many copies) SOCS_box PF07525.11 KFM09806.1 - 1.9e-12 46.8 0.5 3.3e-12 46.0 0.3 1.4 1 0 0 1 1 1 1 SOCS box EF-hand_1 PF00036.27 KFM09807.1 - 1.9e-40 133.0 7.3 3.3e-10 38.5 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KFM09807.1 - 5.3e-36 122.5 1.6 3.9e-20 71.7 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KFM09807.1 - 1.7e-33 113.9 9.1 4.1e-16 58.3 0.3 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 KFM09807.1 - 1.5e-30 102.2 3.5 1.1e-09 37.3 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KFM09807.1 - 3.2e-24 83.1 2.0 6.3e-07 28.4 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 KFM09807.1 - 5.8e-14 51.7 0.1 9.3e-07 28.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KFM09807.1 - 5.5e-08 32.4 0.1 0.00073 19.2 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KFM09807.1 - 1.5e-07 31.3 0.1 0.00053 19.9 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.5 KFM09807.1 - 1.3e-06 28.2 0.7 4.2e-06 26.6 0.2 2.0 2 1 0 2 2 2 1 Ca2+ insensitive EF hand UPF0154 PF03672.8 KFM09807.1 - 1.7e-05 24.3 0.1 0.17 11.5 0.0 3.3 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) Caleosin PF05042.8 KFM09807.1 - 0.0012 18.4 0.1 0.041 13.4 0.1 2.7 1 1 0 1 1 1 1 Caleosin related protein RNA_pol_Rpb4 PF03874.11 KFM09807.1 - 0.0034 17.3 0.2 0.79 9.7 0.2 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb4 TerB PF05099.8 KFM09807.1 - 0.0041 16.8 0.2 2.6 7.7 0.1 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB EF-hand_like PF09279.6 KFM09807.1 - 0.015 15.2 0.4 0.074 13.0 0.1 2.0 2 1 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like DUF3349 PF11829.3 KFM09807.1 - 0.044 14.1 0.1 22 5.5 0.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) DUF1880 PF08976.6 KFM09807.1 - 0.093 12.8 0.0 0.75 9.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) SpoVIF PF14069.1 KFM09807.1 - 0.095 12.4 0.1 1.3 8.7 0.1 2.1 2 0 0 2 2 2 0 Stage VI sporulation protein F Tenui_NCP PF04876.7 KFM09807.1 - 0.11 12.0 0.0 1.4 8.4 0.0 2.0 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein Toprim_2 PF13155.1 KFM09807.1 - 0.13 12.5 0.5 4.5 7.6 0.2 2.3 1 1 1 2 2 2 0 Toprim-like PB1 PF00564.19 KFM09807.1 - 1.1 8.9 3.5 22 4.8 0.3 3.3 3 2 0 3 3 2 0 PB1 domain RhoGEF PF00621.15 KFM09808.1 - 1.4e-37 129.3 0.0 2.6e-37 128.4 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 KFM09808.1 - 4.6e-10 39.6 0.0 8.6e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_5 PF15405.1 KFM09808.1 - 4.9e-09 36.2 0.3 8.5e-08 32.2 0.2 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain Tubulin PF00091.20 KFM09809.1 - 2.3e-71 240.0 0.0 3e-71 239.6 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFM09809.1 - 1.3e-50 170.6 0.0 2e-50 170.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KFM09809.1 - 0.0038 16.7 0.0 0.0075 15.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain V-set PF07686.12 KFM09811.1 - 8.8e-18 64.2 0.2 9.4e-18 64.1 0.1 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 KFM09811.1 - 1.4e-07 31.2 0.0 2.1e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 KFM09811.1 - 3.8e-05 23.7 1.0 0.00012 22.0 0.7 1.7 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFM09811.1 - 0.00012 22.5 2.5 0.00045 20.6 1.7 1.7 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 KFM09811.1 - 0.00068 19.7 0.1 0.00083 19.4 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin domain RRM_1 PF00076.17 KFM09812.1 - 1.6e-45 152.5 2.2 3e-16 58.7 0.0 3.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM09812.1 - 8.8e-38 128.1 0.1 6.8e-14 51.6 0.0 3.6 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM09812.1 - 1.7e-20 72.5 0.2 9.3e-07 28.6 0.1 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KFM09812.1 - 1.5e-05 24.6 1.3 0.05 13.3 0.2 3.6 2 2 1 3 3 3 2 Limkain b1 Calcipressin PF04847.7 KFM09812.1 - 0.012 15.1 0.1 0.3 10.6 0.1 2.7 2 1 1 3 3 3 0 Calcipressin PXA PF02194.10 KFM09813.1 - 9.7e-43 145.8 1.1 1.4e-42 145.4 0.1 1.8 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 KFM09813.1 - 1.7e-24 86.0 0.1 7.8e-24 83.9 0.0 2.3 3 0 0 3 3 3 1 Sorting nexin C terminal PX PF00787.19 KFM09813.1 - 2.3e-20 72.4 1.1 2.3e-20 72.4 0.7 2.8 3 0 0 3 3 3 1 PX domain RGS PF00615.14 KFM09813.1 - 9e-12 45.1 1.7 9e-12 45.1 1.2 2.3 2 0 0 2 2 2 1 Regulator of G protein signaling domain DUF2151 PF10221.4 KFM09813.1 - 1.6 6.7 5.5 2 6.5 0.1 2.8 3 0 0 3 3 3 0 Cell cycle and development regulator 5_nucleotid_C PF02872.13 KFM09814.1 - 8.1e-38 129.8 0.0 1.6e-37 128.8 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 KFM09814.1 - 3.3e-07 29.8 0.1 5.4e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pkinase PF00069.20 KFM09815.1 - 2.6e-71 239.8 0.0 3.2e-71 239.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM09815.1 - 1.7e-40 138.7 0.0 2.3e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM09815.1 - 1.1e-09 37.6 0.0 1.8e-08 33.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFM09815.1 - 3.7e-05 22.8 0.1 6.5e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFM09815.1 - 0.00038 19.8 0.7 0.00074 18.9 0.5 1.5 1 1 0 1 1 1 1 RIO1 family APH PF01636.18 KFM09815.1 - 0.002 17.8 0.0 0.0031 17.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KFM09815.1 - 0.11 11.5 0.7 0.3 10.1 0.2 1.8 1 1 1 2 2 2 0 Ecdysteroid kinase Yae1_N PF09811.4 KFM09816.1 - 4.3e-12 45.3 34.6 22 4.6 24.0 3.4 1 1 0 1 1 1 1 Essential protein Yae1, N terminal T-box PF00907.17 KFM09817.1 - 2.2e-72 242.4 0.0 2.4e-72 242.2 0.0 1.0 1 0 0 1 1 1 1 T-box MRAP PF15183.1 KFM09819.1 - 7.7e-34 115.1 0.1 1.1e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Melanocortin-2 receptor accessory protein family Cyt-b5 PF00173.23 KFM09820.1 - 4.3e-24 84.1 0.0 8.6e-24 83.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.19 KFM09820.1 - 4.1e-16 58.9 0.0 1.4e-15 57.1 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KFM09820.1 - 7.6e-14 52.2 0.0 1.9e-13 50.8 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain CS PF04969.11 KFM09820.1 - 3.1e-10 40.4 2.9 3.1e-10 40.4 0.8 2.0 2 0 0 2 2 2 1 CS domain NAD_binding_6 PF08030.7 KFM09820.1 - 0.00034 20.5 0.2 0.029 14.2 0.0 2.9 1 1 2 3 3 3 1 Ferric reductase NAD binding domain DUF1863 PF08937.6 KFM09820.1 - 0.049 13.6 0.0 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 MTH538 TIR-like domain (DUF1863) Ripply PF14998.1 KFM09821.1 - 7.9e-23 80.3 0.3 1.1e-22 79.9 0.2 1.2 1 0 0 1 1 1 1 Transcription Regulator Trypsin PF00089.21 KFM09822.1 - 5.4e-11 42.4 0.0 5.5e-09 35.9 0.0 2.6 2 1 0 2 2 2 1 Trypsin Trypsin_2 PF13365.1 KFM09822.1 - 3.1e-06 27.1 0.0 1.5e-05 24.9 0.0 2.0 1 1 0 1 1 1 1 Trypsin-like peptidase domain LAP1C PF05609.7 KFM09822.1 - 0.02 13.6 0.0 0.036 12.7 0.0 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF316 PF03761.10 KFM09822.1 - 0.052 12.9 0.0 0.086 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF316) Malic_M PF03949.10 KFM09823.1 - 1.6e-93 312.9 0.3 2e-93 312.6 0.2 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KFM09823.1 - 3.2e-80 267.9 0.0 5.1e-80 267.3 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF1115 PF06544.7 KFM09825.1 - 3.5e-26 91.3 0.1 5.6e-26 90.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) RWD PF05773.17 KFM09825.1 - 6.1e-14 51.8 0.0 1e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 RWD domain Prok-E2_E PF14462.1 KFM09825.1 - 0.025 14.1 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family E PGM_PMM_I PF02878.11 KFM09826.1 - 2.1e-20 72.5 0.1 4.1e-09 36.0 0.0 3.7 2 2 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 KFM09826.1 - 5.2e-12 46.0 0.0 2.9e-11 43.6 0.0 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KFM09826.1 - 2.8e-11 43.2 0.1 1.1e-10 41.3 0.0 2.1 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 KFM09826.1 - 0.00082 19.4 0.4 0.0024 17.9 0.3 1.9 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Frizzled PF01534.12 KFM09826.1 - 0.15 10.8 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Frizzled/Smoothened family membrane region Dopey_N PF04118.9 KFM09827.1 - 2.1e-106 355.1 0.1 1.1e-105 352.7 0.0 2.3 2 0 0 2 2 2 1 Dopey, N-terminal HECT_2 PF09814.4 KFM09828.1 - 1e-77 261.3 1.2 1.2e-77 261.0 0.8 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Rpr2 PF04032.11 KFM09828.1 - 0.062 13.1 0.2 0.85 9.5 0.0 2.3 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-B_box PF00643.19 KFM09828.1 - 0.14 12.0 2.1 2.6 7.9 0.1 2.4 2 0 0 2 2 2 0 B-box zinc finger Tnp_zf-ribbon_2 PF13842.1 KFM09828.1 - 2.9 8.3 10.2 4.4 7.8 0.2 2.8 3 0 0 3 3 3 0 DDE_Tnp_1-like zinc-ribbon RCC1 PF00415.13 KFM09830.1 - 3.1e-35 120.1 15.8 2.2e-11 43.8 1.0 5.1 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 KFM09830.1 - 1.4e-29 102.3 6.6 4.8e-14 52.2 0.6 3.1 2 1 1 3 3 3 2 BTB/POZ domain Ank_5 PF13857.1 KFM09830.1 - 3.4e-13 49.3 0.0 1.3e-06 28.4 0.0 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) RCC1_2 PF13540.1 KFM09830.1 - 2.3e-09 36.6 8.6 0.00037 20.0 0.0 5.9 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat Ank PF00023.25 KFM09830.1 - 4.6e-09 35.6 0.0 8.9e-05 22.1 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 KFM09830.1 - 5.7e-09 36.2 0.0 1.5e-05 25.3 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KFM09830.1 - 1.3e-08 35.0 0.0 4e-08 33.4 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KFM09830.1 - 8.9e-05 22.3 0.0 1.4 9.4 0.0 3.4 2 0 0 2 2 2 2 Ankyrin repeat DUF1693 PF07984.7 KFM09831.1 - 7e-173 574.1 0.2 8e-173 573.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1693) Transket_pyr PF02779.19 KFM09833.1 - 4.1e-43 146.9 0.0 5.5e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KFM09833.1 - 5e-36 123.3 0.4 1.9e-35 121.4 0.0 2.0 3 0 0 3 3 3 1 Transketolase, C-terminal domain Pkinase PF00069.20 KFM09834.1 - 9.6e-63 211.7 1.1 1.6e-62 211.0 0.8 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM09834.1 - 7.6e-34 116.9 0.2 1.4e-33 116.0 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM09834.1 - 1.8e-08 33.6 3.2 4.2e-07 29.2 0.0 3.2 4 0 0 4 4 4 1 Kinase-like APH PF01636.18 KFM09834.1 - 6.7e-06 26.0 0.0 0.21 11.3 0.0 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 KFM09834.1 - 0.00029 19.9 0.0 0.0006 18.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFM09834.1 - 0.0014 17.9 3.3 0.013 14.8 0.1 2.4 1 1 1 2 2 2 1 RIO1 family Tubulin PF00091.20 KFM09834.1 - 0.0037 17.1 0.0 0.0091 15.8 0.0 1.6 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Mad3_BUB1_I PF08311.7 KFM09834.1 - 0.017 14.8 0.1 0.086 12.6 0.0 2.2 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 ELO PF01151.13 KFM09835.1 - 3.1e-66 223.2 24.5 3.7e-66 222.9 17.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family LIME1 PF15332.1 KFM09836.1 - 0.00067 18.9 0.2 0.0032 16.7 0.2 2.0 1 1 0 1 1 1 1 Lck-interacting transmembrane adapter 1 PAG PF15347.1 KFM09836.1 - 0.02 14.0 0.2 0.048 12.7 0.1 1.6 1 1 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched G-patch PF01585.18 KFM09837.1 - 7.5e-12 44.8 0.5 1.7e-11 43.7 0.3 1.6 1 0 0 1 1 1 1 G-patch domain Myb_DNA-binding PF00249.26 KFM09837.1 - 0.092 12.8 0.3 3 7.9 0.1 3.0 3 0 0 3 3 3 0 Myb-like DNA-binding domain G-patch_2 PF12656.2 KFM09837.1 - 0.15 11.9 0.0 0.15 11.9 0.0 2.5 2 0 0 2 2 2 0 DExH-box splicing factor binding site zf-CCCH_2 PF14608.1 KFM09837.1 - 2.8 8.0 5.1 5.3 7.2 3.5 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type DUF1510 PF07423.6 KFM09837.1 - 3.8 6.8 17.3 0.097 12.0 6.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF1664 PF07889.7 KFM09837.1 - 6.6 6.5 7.6 3.9 7.3 1.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) NOA36 PF06524.7 KFM09837.1 - 7.3 5.7 9.0 15 4.7 6.2 1.4 1 0 0 1 1 1 0 NOA36 protein Arf PF00025.16 KFM09838.1 - 8.9e-47 158.5 0.1 1.2e-46 158.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KFM09838.1 - 2.3e-14 53.1 0.1 2.9e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM09838.1 - 2.3e-13 50.6 0.0 2.9e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 KFM09838.1 - 1e-11 44.1 0.1 6.7e-07 28.3 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 KFM09838.1 - 9.4e-11 41.2 0.0 1.2e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KFM09838.1 - 1.5e-07 31.3 0.1 2e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFM09838.1 - 4.5e-07 29.2 0.0 5.4e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFM09838.1 - 0.0029 17.0 0.1 0.02 14.3 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arch_ATPase PF01637.13 KFM09838.1 - 0.0043 16.7 0.1 0.4 10.3 0.0 2.1 1 1 1 2 2 2 1 Archaeal ATPase AAA_18 PF13238.1 KFM09838.1 - 0.01 16.1 0.1 0.014 15.7 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KFM09838.1 - 0.02 14.8 0.4 1.4 8.8 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.1 KFM09838.1 - 0.026 14.6 0.1 0.44 10.6 0.1 2.5 1 1 0 2 2 2 0 AAA domain Stathmin PF00836.14 KFM09839.1 - 3.3e-54 182.3 13.2 4e-54 182.0 9.2 1.1 1 0 0 1 1 1 1 Stathmin family SAND PF01342.16 KFM09840.1 - 6.7e-36 121.8 0.0 1.3e-35 120.9 0.0 1.5 1 0 0 1 1 1 1 SAND domain IncA PF04156.9 KFM09840.1 - 0.044 13.3 0.5 0.07 12.7 0.4 1.3 1 0 0 1 1 1 0 IncA protein Spc7 PF08317.6 KFM09840.1 - 0.34 9.5 3.4 0.12 11.0 0.2 1.7 3 0 0 3 3 3 0 Spc7 kinetochore protein AAA_11 PF13086.1 KFM09841.1 - 9.5e-74 247.9 7.5 2.6e-48 164.6 0.0 5.1 5 1 1 6 6 6 3 AAA domain AAA_12 PF13087.1 KFM09841.1 - 3.5e-70 235.4 0.6 1.2e-43 148.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNB PF00773.14 KFM09841.1 - 2.9e-57 194.4 0.1 1e-56 192.6 0.1 2.0 1 1 0 1 1 1 1 RNB domain AAA_19 PF13245.1 KFM09841.1 - 1.3e-17 63.3 0.0 4.5e-08 32.7 0.0 3.6 3 0 0 3 3 3 2 Part of AAA domain AAA_30 PF13604.1 KFM09841.1 - 3.7e-15 56.0 0.0 0.0044 16.6 0.0 4.5 4 0 0 4 4 4 3 AAA domain AAA_22 PF13401.1 KFM09841.1 - 2.2e-08 34.3 0.1 0.005 16.9 0.0 4.5 5 1 0 5 5 4 2 AAA domain UvrD-helicase PF00580.16 KFM09841.1 - 1.4e-06 27.8 0.1 0.0046 16.3 0.0 3.4 3 0 0 3 3 3 2 UvrD/REP helicase N-terminal domain PhoH PF02562.11 KFM09841.1 - 2.7e-06 26.7 0.2 0.45 9.7 0.0 4.2 4 0 0 4 4 4 2 PhoH-like protein UvrD_C_2 PF13538.1 KFM09841.1 - 3.2e-06 27.2 0.1 0.00029 20.9 0.0 2.9 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD_C PF13361.1 KFM09841.1 - 1.5e-05 24.6 0.0 0.065 12.6 0.0 3.3 2 1 0 2 2 2 2 UvrD-like helicase C-terminal domain ResIII PF04851.10 KFM09841.1 - 1.9e-05 24.6 0.6 0.18 11.5 0.0 3.2 3 0 0 3 3 2 2 Type III restriction enzyme, res subunit zf-met PF12874.2 KFM09841.1 - 3.5e-05 23.8 4.1 0.00015 21.8 2.8 2.2 1 0 0 1 1 1 1 Zinc-finger of C2H2 type T2SE PF00437.15 KFM09841.1 - 0.0005 19.0 0.2 0.064 12.1 0.0 2.6 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF2075 PF09848.4 KFM09841.1 - 0.001 18.1 0.0 0.012 14.6 0.0 2.8 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 KFM09841.1 - 0.001 19.0 0.0 2.3 8.1 0.0 3.0 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.24 KFM09841.1 - 0.0011 19.2 0.1 2.7 8.1 0.0 3.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFM09841.1 - 0.01 15.5 0.0 3.6 7.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DEAD PF00270.24 KFM09841.1 - 0.021 14.3 0.2 3.5 7.0 0.0 3.1 2 2 0 2 2 2 0 DEAD/DEAH box helicase AAA_25 PF13481.1 KFM09841.1 - 0.023 14.1 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.13 KFM09841.1 - 0.066 12.8 0.0 0.2 11.2 0.0 1.8 1 0 0 1 1 1 0 Bacterial dnaA protein Mg_chelatase PF01078.16 KFM09841.1 - 0.066 12.3 0.0 4 6.5 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 KFM09841.1 - 0.16 11.5 0.8 7.2 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 KFM09841.1 - 0.18 11.0 0.0 1.1 8.4 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain zf-C2H2_jaz PF12171.3 KFM09841.1 - 1 9.5 8.5 0.3 11.2 3.2 2.3 2 0 0 2 2 1 0 Zinc-finger double-stranded RNA-binding fn3 PF00041.16 KFM09842.1 - 0.00018 21.6 0.3 0.00037 20.5 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III domain ATS PF15445.1 KFM09842.1 - 0.016 14.3 0.2 0.024 13.7 0.1 1.3 1 0 0 1 1 1 0 acidic terminal segments, variant surface antigen of PfEMP1 Pkinase PF00069.20 KFM09843.1 - 8e-41 139.9 0.0 1.1e-40 139.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM09843.1 - 3.8e-24 85.1 0.0 3.4e-23 82.0 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFM09843.1 - 0.00057 18.9 0.0 0.00092 18.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFM09843.1 - 0.0035 17.1 0.0 0.014 15.1 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KFM09843.1 - 0.0048 15.8 0.0 0.013 14.4 0.0 1.8 1 1 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 KFM09843.1 - 0.0051 16.1 0.0 0.0079 15.5 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 KFM09843.1 - 0.022 13.5 0.1 0.03 13.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PhaC_N PF07167.8 KFM09843.1 - 0.033 13.6 0.0 0.056 12.8 0.0 1.4 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus RIO1 PF01163.17 KFM09843.1 - 0.04 13.2 0.0 0.062 12.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family C1-set PF07654.10 KFM09844.1 - 1.8e-33 114.3 0.8 1.1e-16 60.5 0.1 3.1 3 0 0 3 3 3 2 Immunoglobulin C1-set domain C2-set_2 PF08205.7 KFM09844.1 - 1.2e-22 79.6 0.6 3.7e-10 39.5 0.0 3.2 3 0 0 3 3 3 3 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.1 KFM09844.1 - 1.2e-20 73.3 0.2 2.5e-06 27.5 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 KFM09844.1 - 1.5e-18 66.7 0.1 5.6e-14 52.0 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin V-set domain I-set PF07679.11 KFM09844.1 - 2.2e-17 62.6 0.1 9.8e-08 31.7 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.1 KFM09844.1 - 9.9e-17 61.2 5.8 4.6e-05 23.8 0.2 3.6 3 1 0 3 3 3 3 Immunoglobulin domain ig PF00047.20 KFM09844.1 - 1.7e-15 56.8 7.2 3.7e-08 33.3 0.1 3.9 4 1 0 4 4 4 3 Immunoglobulin domain V-set PF07686.12 KFM09845.1 - 0.0014 18.4 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain DAG1 PF05454.6 KFM09845.1 - 0.017 14.2 0.3 0.05 12.7 0.0 1.7 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) LST1 PF05083.8 KFM09845.1 - 0.037 14.0 2.4 0.16 12.0 0.1 2.3 2 0 0 2 2 2 0 LST-1 protein SIT PF15330.1 KFM09845.1 - 0.082 13.0 1.2 1.1 9.4 0.8 2.1 1 1 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT ig PF00047.20 KFM09845.1 - 0.089 12.9 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain Adeno_E3_CR2 PF02439.10 KFM09845.1 - 0.1 12.1 0.4 0.22 11.0 0.3 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4578 PF15147.1 KFM09845.1 - 0.14 12.5 1.7 0.18 12.2 0.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4578) SEP PF08059.8 KFM09846.1 - 2.5e-28 98.1 0.4 6e-28 96.9 0.0 1.8 2 0 0 2 2 2 1 SEP domain UBX PF00789.15 KFM09846.1 - 8.3e-20 70.6 0.1 1.5e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 UBX domain Spt20 PF12090.3 KFM09846.1 - 0.02 14.2 0.0 0.076 12.3 0.0 1.9 1 1 0 1 1 1 0 Spt20 family FKBP_C PF00254.23 KFM09847.1 - 4.4e-28 97.1 0.0 4.8e-28 97.0 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PDZ PF00595.19 KFM09848.1 - 1.5e-20 73.1 3.5 2.8e-12 46.6 0.0 2.5 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM09848.1 - 4.5e-10 39.2 0.7 1.4e-06 28.1 0.0 2.3 1 1 1 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.1 KFM09848.1 - 0.00086 19.0 0.2 0.4 10.5 0.0 2.4 2 0 0 2 2 2 2 Tricorn protease PDZ domain Syntaphilin PF15290.1 KFM09849.1 - 7.9e-128 426.2 2.5 3.3e-127 424.1 1.7 1.7 1 1 0 1 1 1 1 Golgi-localised syntaxin-1-binding clamp IncA PF04156.9 KFM09849.1 - 0.0023 17.5 6.8 0.0034 17.0 4.7 1.2 1 0 0 1 1 1 1 IncA protein FAM104 PF15434.1 KFM09849.1 - 0.0092 16.1 0.7 0.02 15.0 0.5 1.6 1 0 0 1 1 1 1 Family 104 Spc7 PF08317.6 KFM09849.1 - 0.024 13.2 8.4 0.041 12.5 5.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4200 PF13863.1 KFM09849.1 - 0.026 14.4 3.0 0.026 14.4 2.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF3584 PF12128.3 KFM09849.1 - 0.031 11.6 7.7 0.039 11.3 5.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Sec8_exocyst PF04048.9 KFM09849.1 - 0.032 13.8 8.7 0.77 9.3 0.3 2.2 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Baculo_PEP_C PF04513.7 KFM09849.1 - 0.093 12.5 0.6 0.18 11.6 0.4 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.7 KFM09849.1 - 0.14 11.9 4.0 0.24 11.1 2.7 1.4 1 0 0 1 1 1 0 Laminin Domain II Fez1 PF06818.10 KFM09849.1 - 0.14 12.1 10.7 0.72 9.8 3.9 2.1 1 1 1 2 2 2 0 Fez1 DUF2407_C PF13373.1 KFM09849.1 - 0.21 11.4 1.1 0.32 10.8 0.8 1.3 1 0 0 1 1 1 0 DUF2407 C-terminal domain AAA_13 PF13166.1 KFM09849.1 - 0.22 9.9 6.6 0.28 9.5 4.6 1.1 1 0 0 1 1 1 0 AAA domain BAR PF03114.13 KFM09849.1 - 0.32 10.4 8.0 0.6 9.5 5.6 1.4 1 1 0 1 1 1 0 BAR domain PilJ PF13675.1 KFM09849.1 - 0.39 11.0 3.6 2 8.7 2.2 2.2 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF342 PF03961.8 KFM09849.1 - 0.39 9.0 5.7 0.54 8.6 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Occludin_ELL PF07303.8 KFM09849.1 - 0.41 11.4 6.9 0.58 10.9 4.2 1.6 1 1 0 1 1 1 0 Occludin homology domain HrpB7 PF09486.5 KFM09849.1 - 0.45 10.4 8.1 1.2 8.9 5.6 1.7 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Lebercilin PF15619.1 KFM09849.1 - 0.59 9.5 15.4 1.5 8.1 10.7 1.5 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease MAD PF05557.8 KFM09849.1 - 0.71 7.8 13.7 0.97 7.4 9.5 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein TPR_MLP1_2 PF07926.7 KFM09849.1 - 1.1 8.9 13.2 9.9 5.9 9.0 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Sec2p PF06428.6 KFM09849.1 - 1.1 9.1 13.6 1.5 8.6 0.9 2.7 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Mto2_bdg PF12808.2 KFM09849.1 - 1.8 8.7 9.0 0.75 9.9 1.6 3.3 3 0 0 3 3 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region V_ATPase_I PF01496.14 KFM09849.1 - 2 6.1 4.6 2.8 5.6 3.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4140 PF13600.1 KFM09849.1 - 3.2 8.2 8.3 1.5 9.3 1.1 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Atg14 PF10186.4 KFM09849.1 - 3.6 6.4 12.6 5.6 5.8 8.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF641 PF04859.7 KFM09849.1 - 4 7.1 7.8 0.77 9.5 0.5 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) FlaC_arch PF05377.6 KFM09849.1 - 4.4 7.2 7.4 1.5 8.8 1.2 2.4 2 1 1 3 3 2 0 Flagella accessory protein C (FlaC) Phage_GP20 PF06810.6 KFM09849.1 - 7.3 6.0 16.0 1.9 7.8 1.8 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 Syntaxin PF00804.20 KFM09849.1 - 9.7 6.4 10.4 4.5e+02 1.0 7.2 2.3 1 1 0 1 1 1 0 Syntaxin DivIC PF04977.10 KFM09849.1 - 9.9 5.7 12.7 4.4 6.8 2.4 2.4 1 1 1 2 2 2 0 Septum formation initiator Rad21_Rec8_N PF04825.8 KFM09850.1 - 8e-41 138.4 0.2 5.2e-40 135.8 0.0 2.2 2 1 0 2 2 2 1 N terminus of Rad21 / Rec8 like protein PI31_Prot_N PF11566.3 KFM09851.1 - 1.1e-17 64.0 0.0 1.5e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 KFM09851.1 - 1.9e-08 34.8 15.4 5e-08 33.4 10.7 1.8 1 1 0 1 1 1 1 PI31 proteasome regulator DUF3516 PF12029.3 KFM09851.1 - 0.011 14.6 0.1 0.014 14.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) TSP_1 PF00090.14 KFM09852.1 - 3.1e-05 23.9 10.5 3.1e-05 23.9 7.3 3.0 3 1 0 3 3 3 1 Thrombospondin type 1 domain Fer4_3 PF12798.2 KFM09852.1 - 0.05 14.1 19.8 0.13 12.8 0.0 6.4 6 2 0 6 6 6 0 4Fe-4S binding domain Fibrinogen_C PF00147.13 KFM09853.1 - 8.9e-32 110.5 0.1 2.6e-30 105.7 0.0 2.4 3 0 0 3 3 3 1 Fibrinogen beta and gamma chains, C-terminal globular domain Phage_lysis PF03245.8 KFM09853.1 - 0.0048 16.8 6.4 0.0048 16.8 4.4 2.2 1 1 1 2 2 2 1 Bacteriophage Rz lysis protein DUF1011 PF06237.7 KFM09854.1 - 6.3e-42 141.6 6.7 6.3e-42 141.6 4.6 3.1 3 1 0 3 3 3 1 Protein of unknown function (DUF1011) DUF983 PF06170.7 KFM09854.1 - 1 9.5 13.2 0.055 13.5 1.0 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF983) ParBc PF02195.13 KFM09855.1 - 4.5e-05 23.4 0.0 5.5e-05 23.1 0.0 1.0 1 0 0 1 1 1 1 ParB-like nuclease domain Pkinase PF00069.20 KFM09856.1 - 5.3e-66 222.4 0.3 6.3e-66 222.1 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM09856.1 - 3.5e-21 75.4 0.0 4.8e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFM09856.1 - 6.4e-08 32.6 0.0 1.8e-05 24.5 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KFM09856.1 - 0.0018 17.4 0.0 0.0032 16.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KFM09856.1 - 0.0048 16.4 1.6 0.0056 16.2 0.1 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kinase-like PF14531.1 KFM09856.1 - 0.072 12.0 0.0 0.21 10.5 0.0 1.7 2 0 0 2 2 2 0 Kinase-like RabGAP-TBC PF00566.13 KFM09857.1 - 4e-33 114.6 0.0 5.7e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Peptidase_A22B PF04258.8 KFM09858.1 - 8.4e-99 330.7 8.8 9.8e-99 330.5 6.1 1.0 1 0 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 KFM09858.1 - 0.00019 20.6 7.9 0.00041 19.5 5.5 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1119) Presenilin PF01080.12 KFM09858.1 - 0.0017 17.2 1.1 0.0028 16.5 0.8 1.4 1 0 0 1 1 1 1 Presenilin DUF4345 PF14248.1 KFM09858.1 - 0.036 13.5 0.2 0.036 13.5 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4345) LBP_BPI_CETP_C PF02886.12 KFM09859.1 - 6.3e-28 97.6 0.0 6.8e-28 97.5 0.0 1.0 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain TPX2_importin PF12214.3 KFM09860.1 - 4.1e-57 193.0 57.6 1.6e-55 187.8 4.8 6.4 3 1 2 5 5 5 3 Cell cycle regulated microtubule associated protein Aurora-A_bind PF09041.5 KFM09860.1 - 1.6e-24 85.4 2.8 4.8e-24 83.8 2.0 1.9 1 0 0 1 1 1 1 Aurora-A binding TPX2 PF06886.6 KFM09860.1 - 3.6e-15 55.7 16.6 3.6e-15 55.7 11.5 6.7 8 0 0 8 8 8 1 Targeting protein for Xklp2 (TPX2) Pkinase PF00069.20 KFM09861.1 - 3.9e-45 154.0 0.0 2.8e-38 131.5 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFM09861.1 - 5.4e-28 97.7 0.3 8.4e-28 97.1 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFM09861.1 - 0.011 14.7 0.1 0.019 14.0 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFM09861.1 - 0.12 11.7 0.2 0.21 10.9 0.2 1.3 1 0 0 1 1 1 0 RIO1 family IRF-3 PF10401.4 KFM09862.1 - 9.6e-61 204.4 0.4 1.3e-60 204.0 0.3 1.2 1 0 0 1 1 1 1 Interferon-regulatory factor 3 IRF PF00605.12 KFM09862.1 - 3.3e-19 68.7 0.1 5.2e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor DSPc PF00782.15 KFM09863.1 - 1.9e-33 114.8 0.0 2.7e-33 114.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 KFM09863.1 - 3.9e-07 30.2 0.0 5.6e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 KFM09863.1 - 9.8e-07 28.3 0.1 1.3e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KFM09863.1 - 0.15 12.3 0.6 1.3 9.2 0.3 2.2 2 1 1 3 3 3 0 Tyrosine phosphatase family Prefoldin_2 PF01920.15 KFM09864.1 - 4.8e-06 26.2 1.3 6.6e-06 25.8 0.9 1.2 1 0 0 1 1 1 1 Prefoldin subunit NUDE_C PF04880.8 KFM09864.1 - 0.043 14.1 0.3 0.047 14.0 0.2 1.1 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Prefoldin PF02996.12 KFM09864.1 - 0.048 13.2 0.2 0.06 12.9 0.2 1.1 1 0 0 1 1 1 0 Prefoldin subunit Siah-Interact_N PF09032.6 KFM09864.1 - 0.07 13.1 1.2 0.095 12.7 0.8 1.2 1 0 0 1 1 1 0 Siah interacting protein, N terminal Ribosomal_L29 PF00831.18 KFM09864.1 - 0.092 12.4 2.1 0.18 11.5 1.4 1.5 1 0 0 1 1 1 0 Ribosomal L29 protein TPX2 PF06886.6 KFM09864.1 - 0.2 11.7 2.1 0.3 11.1 1.5 1.3 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) K-box PF01486.12 KFM09864.1 - 0.35 10.6 4.6 0.89 9.3 3.2 1.6 1 1 0 1 1 1 0 K-box region XK-related PF09815.4 KFM09865.1 - 8.9e-103 343.7 22.2 1e-102 343.6 15.4 1.0 1 0 0 1 1 1 1 XK-related protein PI3K_1B_p101 PF10486.4 KFM09867.1 - 0 1449.7 8.6 0 1449.5 5.9 1.0 1 0 0 1 1 1 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit MFS_1 PF07690.11 KFM09869.1 - 1.6e-09 37.0 35.6 4.4e-09 35.5 13.8 3.2 2 1 2 4 4 4 3 Major Facilitator Superfamily MFS_1_like PF12832.2 KFM09869.1 - 0.019 14.7 3.2 0.059 13.1 0.0 2.7 3 0 0 3 3 3 0 MFS_1 like family DUF3585 PF12130.3 KFM09870.1 - 1.1e-33 116.0 16.0 1.4e-33 115.7 11.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3585) Hep_59 PF07052.6 KFM09870.1 - 0.049 13.9 3.2 0.32 11.3 0.2 2.2 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 NACHT PF05729.7 KFM09870.1 - 0.093 12.3 0.4 0.11 12.0 0.3 1.2 1 0 0 1 1 1 0 NACHT domain Histone_HNS PF00816.16 KFM09870.1 - 0.1 13.0 5.7 0.18 12.3 3.9 1.6 1 1 0 1 1 1 0 H-NS histone family SPX PF03105.14 KFM09870.1 - 0.39 10.4 4.9 0.45 10.2 3.4 1.2 1 0 0 1 1 1 0 SPX domain DUF2120 PF09893.4 KFM09870.1 - 0.64 9.9 4.6 0.91 9.4 3.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) FlxA PF14282.1 KFM09870.1 - 5.4 7.0 9.2 0.43 10.5 2.8 1.8 2 0 0 2 2 2 0 FlxA-like protein AAA_23 PF13476.1 KFM09870.1 - 9.2 6.5 10.8 12 6.0 7.5 1.2 1 0 0 1 1 1 0 AAA domain DUF4200 PF13863.1 KFM09871.1 - 2.5e-20 72.6 26.8 2.5e-20 72.6 18.6 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4200) BSD PF03909.12 KFM09871.1 - 0.047 13.4 1.3 5.5 6.8 0.2 3.1 1 1 1 2 2 2 0 BSD domain Coatamer_beta_C PF07718.7 KFM09871.1 - 0.052 13.1 1.3 0.1 12.2 0.6 1.7 1 1 0 1 1 1 0 Coatomer beta C-terminal region SWI-SNF_Ssr4 PF08549.5 KFM09871.1 - 1 7.5 6.5 1.4 7.1 4.5 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Succ_DH_flav_C PF02910.15 KFM09871.1 - 1.1 9.1 9.6 4 7.2 0.5 3.1 1 1 2 3 3 3 0 Fumarate reductase flavoprotein C-term Fib_alpha PF08702.5 KFM09871.1 - 4.8 7.2 18.8 3.4 7.7 5.8 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family RGS PF00615.14 KFM09871.1 - 7.1 6.7 10.2 0.42 10.7 2.0 2.4 1 1 1 2 2 2 0 Regulator of G protein signaling domain Myosin_head PF00063.16 KFM09872.1 - 1.2e-287 955.6 0.2 1.2e-287 955.6 0.1 4.5 3 1 1 4 4 4 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 KFM09872.1 - 8.2e-196 652.4 313.2 3.9e-193 643.5 161.0 2.9 1 1 0 2 2 2 2 Myosin tail Myosin_N PF02736.14 KFM09872.1 - 7.5e-13 47.9 1.0 1.4e-12 47.0 0.1 1.9 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain IQ PF00612.22 KFM09872.1 - 0.0001 21.6 0.1 0.00034 20.0 0.1 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif ADIP PF11559.3 KFM09872.1 - 0.00012 22.0 20.9 0.00012 22.0 14.5 13.3 1 1 12 14 14 14 7 Afadin- and alpha -actinin-Binding DUF1664 PF07889.7 KFM09872.1 - 0.005 16.6 9.0 0.005 16.6 6.2 12.3 3 3 6 12 12 12 2 Protein of unknown function (DUF1664) Reo_sigmaC PF04582.7 KFM09872.1 - 0.61 9.2 68.9 0.37 9.9 0.5 8.2 2 2 2 8 8 8 0 Reovirus sigma C capsid protein NUDE_C PF04880.8 KFM09873.1 - 1.2e-71 240.4 1.0 1.2e-71 240.4 0.7 2.8 2 1 1 3 3 3 1 NUDE protein, C-terminal conserved region HALZ PF02183.13 KFM09873.1 - 0.0094 15.6 2.9 0.0094 15.6 2.0 3.1 3 0 0 3 3 3 1 Homeobox associated leucine zipper CCDC92 PF14916.1 KFM09873.1 - 0.53 9.9 8.7 0.64 9.6 0.0 3.5 2 1 1 3 3 3 0 Coiled-coil domain of unknown function ERM PF00769.14 KFM09873.1 - 0.74 9.2 31.4 0.074 12.5 9.2 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family KxDL PF10241.4 KFM09873.1 - 0.98 9.3 15.1 0.039 13.8 2.8 3.2 3 1 1 4 4 4 0 Uncharacterized conserved protein DUF972 PF06156.8 KFM09873.1 - 1.1 9.6 20.4 5.6 7.3 3.4 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF972) TPR_MLP1_2 PF07926.7 KFM09873.1 - 1.2 8.8 29.6 0.056 13.1 6.2 2.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1759 PF03564.10 KFM09873.1 - 1.5 8.6 9.3 3.1 7.5 2.5 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1759) Sigma54_AID PF00309.15 KFM09873.1 - 1.5 8.3 6.4 0.34 10.4 0.4 2.8 2 0 0 2 2 2 0 Sigma-54 factor, Activator interacting domain (AID) GAS PF13851.1 KFM09873.1 - 1.5 7.9 29.6 1.7 7.8 11.5 2.8 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 KFM09873.1 - 1.8 8.4 30.6 0.4 10.5 15.7 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Striatin PF08232.7 KFM09873.1 - 1.9 8.7 21.3 7.9 6.7 5.6 3.7 2 1 1 3 3 3 0 Striatin family Rootletin PF15035.1 KFM09873.1 - 3.2 7.6 32.4 2.6 8.0 8.6 2.3 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF2051 PF09738.4 KFM09873.1 - 5.9 6.0 30.4 2.3 7.4 10.3 3.0 2 1 2 4 4 4 0 Double stranded RNA binding protein (DUF2051) DUF1664 PF07889.7 KFM09873.1 - 6.4 6.5 9.7 15 5.3 0.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DMPK_coil PF08826.5 KFM09873.1 - 6.5 6.7 25.4 0.046 13.6 6.1 3.6 2 1 1 3 3 3 0 DMPK coiled coil domain like DUF904 PF06005.7 KFM09873.1 - 7.8 6.8 32.6 3.4 8.0 3.5 3.9 1 1 2 3 3 3 0 Protein of unknown function (DUF904) Tropomyosin_1 PF12718.2 KFM09873.1 - 8.1 6.2 32.0 27 4.6 16.2 3.2 1 1 1 2 2 2 0 Tropomyosin like zf-RING_2 PF13639.1 KFM09874.1 - 2.3e-09 36.9 11.2 4.7e-09 35.9 7.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KFM09874.1 - 8.3e-07 28.6 11.3 1.9e-06 27.4 7.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFM09874.1 - 1.9e-05 24.5 12.0 4.5e-05 23.3 8.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFM09874.1 - 5.7e-05 22.7 7.7 5.8e-05 22.7 3.6 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.20 KFM09874.1 - 7.6e-05 22.2 11.8 0.00016 21.2 8.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM09874.1 - 0.0001 21.9 9.5 0.0001 21.9 6.6 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KFM09874.1 - 0.0014 18.1 7.3 0.0028 17.1 5.0 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain FYVE PF01363.16 KFM09874.1 - 0.0021 17.9 5.8 0.0021 17.9 4.0 1.7 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.11 KFM09874.1 - 0.11 12.3 5.3 0.053 13.4 2.0 1.6 2 0 0 2 2 2 0 FYVE-type zinc finger GAGA PF09237.6 KFM09874.1 - 0.16 11.6 3.3 3 7.4 0.1 2.4 2 0 0 2 2 2 0 GAGA factor zf-C3HC4_4 PF15227.1 KFM09874.1 - 0.31 10.9 16.0 0.21 11.5 8.5 2.7 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-MIZ PF02891.15 KFM09874.1 - 7 6.2 12.1 31 4.1 8.4 2.1 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger PIRT PF15099.1 KFM09875.1 - 5.8e-49 164.6 0.2 6.7e-49 164.3 0.2 1.0 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family L_HGMIC_fpl PF10242.4 KFM09875.1 - 0.00047 20.2 0.4 0.00053 20.0 0.3 1.1 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein 7TM_GPCR_Srz PF10325.4 KFM09875.1 - 0.0024 17.0 1.3 0.0029 16.7 0.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srz Neurensin PF14927.1 KFM09875.1 - 0.0087 15.4 1.8 0.28 10.5 0.0 2.1 1 1 0 2 2 2 1 Neurensin Claudin_2 PF13903.1 KFM09875.1 - 0.018 14.7 0.3 0.022 14.4 0.2 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF2663 PF10864.3 KFM09875.1 - 0.024 14.8 0.1 0.033 14.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) SdpI PF13630.1 KFM09875.1 - 0.038 13.7 3.9 0.8 9.4 2.7 2.1 1 1 0 1 1 1 0 SdpI/YhfL protein family Ferric_reduct PF01794.14 KFM09875.1 - 0.076 13.1 0.7 0.17 11.9 0.1 1.8 1 1 0 1 1 1 0 Ferric reductase like transmembrane component YajC PF02699.10 KFM09875.1 - 0.082 12.5 0.2 0.082 12.5 0.2 1.7 2 0 0 2 2 2 0 Preprotein translocase subunit zf-RING_2 PF13639.1 KFM09876.1 - 1.3e-13 50.5 9.4 1.3e-13 50.5 6.5 2.7 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 KFM09876.1 - 2.5e-07 30.7 4.5 2.5e-07 30.7 3.1 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KFM09876.1 - 2.8e-06 26.8 8.7 2.8e-06 26.8 6.0 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM09876.1 - 4.1e-06 26.7 8.8 4.1e-06 26.7 6.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM09876.1 - 1.7e-05 24.4 6.1 1.7e-05 24.4 4.2 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM09876.1 - 2e-05 24.2 7.7 9.6e-05 22.0 5.3 2.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KFM09876.1 - 0.017 14.9 3.3 0.076 12.8 2.3 2.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DGF-1_C PF11040.3 KFM09877.1 - 0.078 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Sugar_tr PF00083.19 KFM09879.1 - 1.7e-95 320.2 21.4 2.1e-95 319.9 14.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFM09879.1 - 1.5e-20 73.2 23.6 1.5e-20 73.2 16.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily C_GCAxxG_C_C PF09719.5 KFM09879.1 - 0.034 13.9 0.1 0.085 12.6 0.0 1.7 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) MFS_3 PF05977.8 KFM09879.1 - 0.27 9.2 6.4 0.14 10.2 0.2 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Romo1 PF10247.4 KFM09879.1 - 2.8 8.1 12.5 2.4 8.4 0.6 3.2 3 0 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 Pkinase PF00069.20 KFM09880.1 - 8.7e-74 247.9 0.0 1.2e-73 247.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM09880.1 - 8.7e-32 110.2 0.0 1.2e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KFM09880.1 - 2.8e-13 49.7 0.0 5.7e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 KFM09880.1 - 1.4e-07 30.8 0.0 1.9e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 KFM09880.1 - 0.0045 15.8 0.1 0.012 14.4 0.0 1.6 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.4 KFM09880.1 - 0.023 14.0 0.0 0.049 12.9 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 KFM09880.1 - 0.051 12.6 0.0 0.083 11.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFM09880.1 - 0.079 12.2 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family TPR_12 PF13424.1 KFM09881.1 - 5.6e-106 346.6 109.4 2.9e-13 49.5 0.1 14.8 9 2 8 17 17 17 16 Tetratricopeptide repeat TPR_7 PF13176.1 KFM09881.1 - 4.1e-87 279.2 85.8 1e-06 28.0 0.1 24.8 24 0 0 24 24 24 19 Tetratricopeptide repeat CHAT PF12770.2 KFM09881.1 - 1.4e-77 260.6 0.1 2.8e-77 259.6 0.1 1.6 1 0 0 1 1 1 1 CHAT domain TPR_1 PF00515.23 KFM09881.1 - 1.6e-77 252.1 96.7 1.8e-07 30.4 0.7 22.8 23 0 0 23 23 23 18 Tetratricopeptide repeat TPR_11 PF13414.1 KFM09881.1 - 1.9e-69 229.2 89.1 7.3e-10 38.3 3.0 15.2 12 3 2 14 14 14 13 TPR repeat TPR_2 PF07719.12 KFM09881.1 - 8.7e-49 159.5 97.6 1.3e-06 27.8 1.1 23.9 25 0 0 25 25 24 12 Tetratricopeptide repeat TPR_8 PF13181.1 KFM09881.1 - 8.6e-42 137.8 78.3 6.6e-07 28.6 0.6 22.5 23 0 0 23 23 23 10 Tetratricopeptide repeat TPR_10 PF13374.1 KFM09881.1 - 4.9e-33 112.1 84.0 0.0011 18.8 0.1 23.1 24 0 0 24 24 24 11 Tetratricopeptide repeat TPR_14 PF13428.1 KFM09881.1 - 1.2e-23 81.4 62.2 0.017 15.7 0.0 21.9 19 5 6 25 25 25 5 Tetratricopeptide repeat Rapsyn_N PF10579.4 KFM09881.1 - 3.2e-15 55.6 22.4 0.015 15.1 0.1 11.8 8 3 2 10 10 10 2 Rapsyn N-terminal myristoylation and linker region TPR_16 PF13432.1 KFM09881.1 - 6.7e-14 52.1 77.3 0.0063 17.1 0.3 15.0 10 2 9 19 19 18 9 Tetratricopeptide repeat TPR_4 PF07721.9 KFM09881.1 - 9.9e-11 41.0 32.7 1.4 9.5 0.6 15.0 15 0 0 15 15 14 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFM09881.1 - 6.1e-07 29.6 56.0 0.11 12.8 0.5 11.8 9 5 4 13 13 13 4 Tetratricopeptide repeat RPN7 PF10602.4 KFM09881.1 - 1.3e-06 27.9 35.4 0.067 12.5 0.1 8.8 6 2 1 7 7 7 3 26S proteasome subunit RPN7 TPR_17 PF13431.1 KFM09881.1 - 8.6e-06 25.5 56.1 2.8 8.3 0.0 17.4 19 0 0 19 19 18 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFM09881.1 - 0.00028 21.1 53.5 0.039 14.3 0.0 16.5 20 0 0 20 20 17 1 Tetratricopeptide repeat PUB PF09409.5 KFM09881.1 - 0.00042 20.0 0.0 1.5 8.6 0.0 2.7 2 0 0 2 2 2 2 PUB domain Apc5 PF12862.2 KFM09881.1 - 0.0082 15.9 27.2 0.12 12.2 0.1 9.0 9 2 1 10 10 9 1 Anaphase-promoting complex subunit 5 TPR_9 PF13371.1 KFM09881.1 - 0.012 15.4 0.1 0.012 15.4 0.1 12.3 12 3 2 14 14 14 0 Tetratricopeptide repeat Apc3 PF12895.2 KFM09881.1 - 0.052 13.6 67.8 0.039 14.0 4.9 10.3 3 2 8 13 13 13 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 KFM09881.1 - 5.2 6.9 32.9 2.9 7.7 0.2 9.1 11 0 0 11 11 10 0 Tetratricopeptide repeat IP_trans PF02121.13 KFM09882.1 - 3.8e-127 422.7 3.2 4.2e-127 422.5 2.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Crystall PF00030.14 KFM09883.1 - 1.3e-52 175.6 4.8 1e-26 92.6 0.5 2.1 2 0 0 2 2 2 2 Beta/Gamma crystallin Crystall PF00030.14 KFM09884.1 - 8.7e-59 195.3 4.2 3.1e-29 100.6 0.3 2.1 2 0 0 2 2 2 2 Beta/Gamma crystallin Crystall_3 PF08964.5 KFM09884.1 - 8.4e-07 28.6 0.1 0.011 15.4 0.0 2.8 2 2 1 3 3 3 2 Beta/Gamma crystallin Inhibitor_I36 PF03995.8 KFM09884.1 - 0.0014 18.9 0.1 0.22 11.9 0.0 2.4 1 1 1 2 2 2 2 Peptidase inhibitor family I36 Sulfotransfer_3 PF13469.1 KFM09885.1 - 6.3e-12 46.6 0.0 1.4e-11 45.6 0.0 1.6 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 KFM09885.1 - 3.3e-07 29.8 0.1 2.6e-06 26.8 0.1 2.2 1 1 0 1 1 1 1 Sulfotransferase domain GCFC PF07842.7 KFM09886.1 - 1.7e-98 329.3 17.1 6.5e-98 327.4 10.3 2.2 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 KFM09886.1 - 3.9e-16 58.5 4.7 7.7e-16 57.6 3.3 1.5 1 0 0 1 1 1 1 G-patch domain TIP_N PF12457.3 KFM09886.1 - 0.001 19.1 0.6 0.001 19.1 0.5 1.8 2 0 0 2 2 2 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.2 KFM09886.1 - 0.0022 17.7 1.0 0.0022 17.7 0.7 2.0 2 0 0 2 2 2 1 DExH-box splicing factor binding site Asp_Arg_Hydrox PF05118.10 KFM09889.1 - 1.9e-32 112.3 0.0 2.7e-32 111.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Sushi PF00084.15 KFM09890.1 - 6.9e-37 125.6 20.6 4.1e-10 39.8 1.3 4.3 4 0 0 4 4 4 4 Sushi domain (SCR repeat) CUB PF00431.15 KFM09890.1 - 1.1e-20 73.7 0.0 3.2e-19 69.0 0.0 2.6 2 0 0 2 2 2 1 CUB domain Myosin_head PF00063.16 KFM09891.1 - 3e-96 323.0 0.0 1.2e-95 321.0 0.0 2.1 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 KFM09891.1 - 1.3e-18 66.1 124.2 2.3e-18 65.3 41.6 3.6 2 1 1 3 3 3 2 Myosin tail ADIP PF11559.3 KFM09891.1 - 0.0014 18.5 14.1 0.0014 18.5 9.8 8.9 4 3 5 9 9 9 1 Afadin- and alpha -actinin-Binding CALCOCO1 PF07888.6 KFM09891.1 - 0.0016 16.8 31.2 0.0016 16.8 21.6 4.1 1 1 1 3 3 3 1 Calcium binding and coiled-coil domain (CALCOCO1) like IQ PF00612.22 KFM09891.1 - 0.016 14.7 2.7 0.058 13.0 0.2 3.0 2 0 0 2 2 2 0 IQ calmodulin-binding motif Pkinase PF00069.20 KFM09892.1 - 1.3e-70 237.4 0.0 5.9e-70 235.3 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM09892.1 - 1.1e-28 100.0 0.0 1.7e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.14 KFM09892.1 - 5.9e-20 71.5 4.9 1.1e-19 70.6 3.4 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain PH PF00169.24 KFM09892.1 - 1.6e-10 41.1 0.2 3.6e-10 39.9 0.1 1.7 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 KFM09892.1 - 0.00067 18.7 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFM09892.1 - 0.032 13.3 0.1 0.061 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PH_11 PF15413.1 KFM09892.1 - 0.16 12.2 2.8 0.31 11.2 0.3 2.5 2 1 0 2 2 2 0 Pleckstrin homology domain Crystall PF00030.14 KFM09893.1 - 1.4e-59 197.9 1.8 9e-30 102.4 0.1 2.0 2 0 0 2 2 2 2 Beta/Gamma crystallin Crystall_3 PF08964.5 KFM09893.1 - 2.6e-05 23.8 2.0 0.0038 16.9 0.2 3.2 3 1 0 3 3 3 2 Beta/Gamma crystallin Inhibitor_I36 PF03995.8 KFM09893.1 - 0.071 13.4 0.1 2.2 8.7 0.0 2.3 1 1 1 2 2 2 0 Peptidase inhibitor family I36 Crystall PF00030.14 KFM09894.1 - 5.8e-57 189.5 0.4 3.4e-28 97.3 0.1 2.0 2 0 0 2 2 2 2 Beta/Gamma crystallin Crystall_3 PF08964.5 KFM09894.1 - 0.0046 16.6 0.0 3.8 7.3 0.0 3.3 3 1 0 3 3 3 2 Beta/Gamma crystallin Tankyrase_bdg_C PF15327.1 KFM09895.1 - 2.7e-61 206.8 14.8 2.7e-61 206.8 10.3 5.5 5 1 1 6 6 6 1 Tankyrase binding protein C terminal domain Ldl_recept_a PF00057.13 KFM09896.1 - 2.3e-39 132.9 84.7 8.7e-12 44.7 8.4 5.5 5 0 0 5 5 5 5 Low-density lipoprotein receptor domain class A CUB PF00431.15 KFM09896.1 - 3.8e-33 113.8 0.4 8.2e-22 77.3 0.0 2.4 2 0 0 2 2 2 2 CUB domain AA_permease_2 PF13520.1 KFM09897.1 - 6.1e-62 209.5 42.6 7.5e-62 209.2 29.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFM09897.1 - 2.6e-37 128.3 35.9 3.2e-37 127.9 24.9 1.1 1 0 0 1 1 1 1 Amino acid permease bZIP_2 PF07716.10 KFM09898.1 - 6.1e-15 54.7 11.3 1.1e-14 53.9 7.8 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KFM09898.1 - 0.00011 22.0 6.1 0.00021 21.2 4.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor IBB PF01749.15 KFM09898.1 - 0.026 14.6 9.5 0.054 13.6 6.6 1.4 1 0 0 1 1 1 0 Importin beta binding domain Exo_endo_phos_2 PF14529.1 KFM09898.1 - 0.042 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Myc-LZ PF02344.10 KFM09898.1 - 0.11 12.0 2.4 0.3 10.7 1.7 1.6 1 0 0 1 1 1 0 Myc leucine zipper domain PAT1 PF09770.4 KFM09898.1 - 0.35 9.0 13.1 0.5 8.5 9.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pox_A_type_inc PF04508.7 KFM09898.1 - 6.8 6.7 6.0 1.1 9.2 1.2 1.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat bZIP_2 PF07716.10 KFM09899.1 - 4.5e-16 58.4 17.0 6.2e-16 57.9 11.8 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KFM09899.1 - 5.6e-06 26.2 12.6 9.4e-06 25.4 8.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor DUF572 PF04502.8 KFM09899.1 - 0.001 18.4 1.1 0.001 18.4 0.8 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) IncA PF04156.9 KFM09899.1 - 0.011 15.3 0.3 0.012 15.1 0.2 1.2 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 KFM09899.1 - 0.02 12.7 5.6 0.024 12.5 3.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Herpes_UL6 PF01763.11 KFM09899.1 - 0.022 12.9 1.2 0.024 12.8 0.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Seryl_tRNA_N PF02403.17 KFM09899.1 - 0.032 14.2 7.8 0.051 13.6 5.4 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain bZIP_Maf PF03131.12 KFM09899.1 - 0.041 14.1 7.6 0.073 13.3 5.3 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Atg14 PF10186.4 KFM09899.1 - 0.1 11.5 5.6 0.14 11.0 3.9 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DivIC PF04977.10 KFM09899.1 - 0.2 11.1 7.4 0.23 10.9 4.3 1.6 1 1 0 1 1 1 0 Septum formation initiator APG6 PF04111.7 KFM09899.1 - 0.3 10.0 5.9 0.35 9.8 4.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4094 PF13334.1 KFM09899.1 - 0.75 10.2 6.0 0.26 11.6 2.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) LAM_C PF12544.3 KFM09899.1 - 2.1 8.3 6.7 19 5.2 4.6 2.2 1 1 0 1 1 1 0 Lysine-2,3-aminomutase XhlA PF10779.4 KFM09899.1 - 4.2 7.3 5.9 7.6 6.5 4.1 1.4 1 0 0 1 1 1 0 Haemolysin XhlA Peptidase_M24 PF00557.19 KFM09900.1 - 8.5e-61 205.1 0.0 2.1e-58 197.3 0.0 2.9 3 0 0 3 3 3 1 Metallopeptidase family M24 AMP_N PF05195.11 KFM09900.1 - 5.8e-42 142.2 0.0 1e-41 141.4 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF3793 PF12672.2 KFM09900.1 - 0.048 13.2 1.5 4 6.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3793) Sulfotransfer_2 PF03567.9 KFM09902.1 - 7.4e-57 192.9 3.9 9.1e-57 192.6 2.7 1.1 1 0 0 1 1 1 1 Sulfotransferase family BTB_2 PF02214.17 KFM09903.1 - 7.8e-17 61.2 0.1 1.2e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain TAF4 PF05236.9 KFM09904.1 - 3.5e-83 278.9 5.0 4e-83 278.7 3.5 1.0 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family TAF PF02969.12 KFM09904.1 - 0.00011 22.0 1.0 0.18 11.7 0.0 2.6 2 0 0 2 2 2 2 TATA box binding protein associated factor (TAF) SAGA-Tad1 PF12767.2 KFM09904.1 - 0.00018 21.2 2.3 0.0085 15.7 0.0 2.2 2 0 0 2 2 2 2 Transcriptional regulator of RNA polII, SAGA, subunit SprA-related PF12118.3 KFM09904.1 - 0.088 12.1 7.9 0.097 11.9 5.4 1.1 1 0 0 1 1 1 0 SprA-related family Peptidase_S46 PF10459.4 KFM09904.1 - 2.3 6.5 8.9 2.9 6.1 6.2 1.1 1 0 0 1 1 1 0 Peptidase S46 LSM14 PF12701.2 KFM09905.1 - 3.3e-42 142.2 0.0 7e-42 141.1 0.0 1.6 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 KFM09905.1 - 6.6e-32 110.1 8.3 6.6e-32 110.1 5.7 2.0 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.1 KFM09905.1 - 2.9e-06 27.1 0.0 7.6e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 Ataxin 2 SM domain GRP PF07172.6 KFM09905.1 - 2.1 8.9 17.6 15 6.1 7.9 2.6 2 0 0 2 2 2 0 Glycine rich protein family DUF3729 PF12526.3 KFM09905.1 - 7.8 7.8 11.7 1.7 10.0 5.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3729) SSXT PF05030.7 KFM09906.1 - 1.2e-28 98.4 0.1 1.3e-28 98.3 0.1 1.0 1 0 0 1 1 1 1 SSXT protein (N-terminal region) TINF2_N PF14973.1 KFM09908.1 - 0.053 13.6 0.0 0.096 12.8 0.0 1.4 1 1 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus PGI PF00342.14 KFM09909.1 - 3.4e-239 794.2 0.0 3.8e-239 794.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF4473 PF14747.1 KFM09909.1 - 0.029 14.6 0.7 0.13 12.4 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4473) LIM PF00412.17 KFM09911.1 - 4.8e-36 122.6 37.3 3.9e-14 52.4 6.3 3.1 3 0 0 3 3 3 3 LIM domain UBACT PF02134.16 KFM09912.1 - 4.8e-27 93.3 0.1 8.2e-27 92.5 0.1 1.4 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein ThiF PF00899.16 KFM09912.1 - 3.1e-24 85.3 0.1 6.4e-24 84.3 0.0 1.6 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.1 KFM09912.1 - 3.8e-24 84.5 1.3 3.8e-24 84.5 0.9 2.3 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.4 KFM09912.1 - 1.2e-22 79.0 2.4 1.2e-22 79.0 1.7 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site PDCD2_C PF04194.8 KFM09913.1 - 2.4e-54 183.3 0.1 4.6e-54 182.4 0.1 1.4 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain Rad50_zn_hook PF04423.9 KFM09913.1 - 3.7 7.0 5.6 16 5.0 0.1 2.7 3 0 0 3 3 3 0 Rad50 zinc hook motif COesterase PF00135.23 KFM09914.1 - 2.5e-164 547.9 0.0 2.8e-164 547.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFM09914.1 - 1.8e-09 37.4 3.4 5.5e-09 35.9 1.6 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFM09914.1 - 0.00025 20.3 0.0 0.00039 19.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2424 PF10340.4 KFM09914.1 - 0.0013 17.4 0.0 0.0022 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Esterase PF00756.15 KFM09914.1 - 0.027 13.9 1.2 0.071 12.5 0.8 1.6 1 1 0 1 1 1 0 Putative esterase DUF59 PF01883.14 KFM09915.1 - 1.5e-11 44.0 0.1 3.7e-11 42.8 0.0 1.7 1 1 1 2 2 2 1 Domain of unknown function DUF59 Ras PF00071.17 KFM09916.1 - 3.5e-31 107.7 0.0 5e-31 107.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM09916.1 - 6.7e-19 68.5 0.0 1.2e-18 67.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM09916.1 - 0.0017 17.6 0.0 0.0025 17.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.13 KFM09916.1 - 0.0017 17.6 0.1 0.017 14.4 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.1 KFM09916.1 - 0.0056 16.8 0.1 1.7 8.7 0.0 3.0 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.1 KFM09916.1 - 0.013 15.7 1.1 0.054 13.7 0.8 2.0 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KFM09916.1 - 0.014 15.0 0.1 0.066 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KFM09916.1 - 0.017 15.4 0.3 0.058 13.6 0.2 1.9 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 KFM09916.1 - 0.023 14.6 0.1 0.67 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 KFM09916.1 - 0.033 14.3 0.3 0.3 11.2 0.2 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) GTP_EFTU PF00009.22 KFM09916.1 - 0.035 13.5 0.2 0.083 12.3 0.0 1.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_5 PF07728.9 KFM09916.1 - 0.11 12.1 0.2 0.3 10.8 0.2 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PP2C PF00481.16 KFM09917.1 - 3.2e-40 138.1 0.0 3.4e-37 128.2 0.0 2.2 1 1 1 2 2 2 2 Protein phosphatase 2C Carb_anhydrase PF00194.16 KFM09918.1 - 5.1e-113 376.2 0.0 5.6e-113 376.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Drf_GBD PF06371.8 KFM09919.1 - 0.0099 15.2 2.0 0.032 13.5 0.3 2.4 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Atx10homo_assoc PF09759.4 KFM09919.1 - 0.035 13.8 3.9 5 6.9 0.3 3.2 3 1 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain DLIC PF05783.6 KFM09921.1 - 1.8e-244 811.7 0.0 2e-244 811.5 0.0 1.0 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) GTP_EFTU PF00009.22 KFM09921.1 - 0.002 17.6 0.3 0.95 8.8 0.0 2.6 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 KFM09921.1 - 0.0024 18.1 0.0 0.0045 17.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter Miro PF08477.8 KFM09921.1 - 0.0038 17.7 0.1 0.046 14.2 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_18 PF13238.1 KFM09921.1 - 0.005 17.1 0.1 0.016 15.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KFM09921.1 - 0.0077 15.7 0.3 0.017 14.6 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KFM09921.1 - 0.023 14.6 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Arf PF00025.16 KFM09921.1 - 0.026 13.7 0.2 0.33 10.1 0.0 2.5 3 0 0 3 3 3 0 ADP-ribosylation factor family NACHT PF05729.7 KFM09921.1 - 0.027 14.1 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain FtsK_SpoIIIE PF01580.13 KFM09921.1 - 0.038 13.4 0.3 0.24 10.8 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family PduV-EutP PF10662.4 KFM09921.1 - 0.04 13.4 0.5 0.14 11.6 0.1 2.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 KFM09921.1 - 0.056 13.5 0.0 0.19 11.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.1 KFM09921.1 - 0.062 12.7 0.0 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain Kinesin PF00225.18 KFM09921.1 - 0.062 11.9 0.0 0.09 11.4 0.0 1.2 1 0 0 1 1 1 0 Kinesin motor domain AAA_10 PF12846.2 KFM09921.1 - 0.085 12.2 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_17 PF13207.1 KFM09921.1 - 0.1 13.4 0.9 0.75 10.6 0.6 2.4 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 KFM09921.1 - 0.1 11.6 0.1 0.2 10.7 0.1 1.5 1 1 0 1 1 1 0 KaiC AAA_23 PF13476.1 KFM09921.1 - 0.12 12.7 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KFM09921.1 - 0.14 11.7 0.3 0.3 10.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain MARVEL PF01284.18 KFM09922.1 - 8.3e-14 51.6 14.7 1.2e-13 51.0 10.2 1.3 1 0 0 1 1 1 1 Membrane-associating domain YfhO PF09586.5 KFM09922.1 - 0.0018 16.3 0.5 0.0021 16.1 0.3 1.0 1 0 0 1 1 1 1 Bacterial membrane protein YfhO YbhQ PF11076.3 KFM09922.1 - 0.023 14.3 0.7 0.026 14.1 0.5 1.1 1 0 0 1 1 1 0 Putative inner membrane protein YbhQ NicO PF03824.11 KFM09922.1 - 0.041 13.2 0.4 0.041 13.2 0.3 1.8 1 1 1 2 2 2 0 High-affinity nickel-transport protein RseC_MucC PF04246.7 KFM09922.1 - 0.048 13.2 0.4 0.048 13.2 0.3 1.6 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF2177 PF09945.4 KFM09922.1 - 0.13 12.1 2.9 0.19 11.6 2.0 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2177) ABC2_membrane_2 PF12679.2 KFM09922.1 - 0.36 9.6 4.0 0.44 9.3 2.8 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein NfeD PF01957.13 KFM09922.1 - 0.58 10.2 6.4 0.81 9.8 1.9 2.0 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding Neur_chan_memb PF02932.11 KFM09922.1 - 1.1 9.1 3.4 2.9 7.6 0.6 2.0 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region MARVEL PF01284.18 KFM09923.1 - 1.8e-08 34.3 15.8 3.3e-08 33.4 10.9 1.5 1 1 0 1 1 1 1 Membrane-associating domain Cad PF03596.8 KFM09923.1 - 0.024 14.3 1.1 0.04 13.6 0.7 1.3 1 0 0 1 1 1 0 Cadmium resistance transporter PHO4 PF01384.15 KFM09923.1 - 0.033 12.8 3.0 0.039 12.6 2.1 1.0 1 0 0 1 1 1 0 Phosphate transporter family GtrA PF04138.9 KFM09923.1 - 1.7 8.6 11.4 4.8 7.1 7.9 1.7 1 1 0 1 1 1 0 GtrA-like protein O-antigen_lig PF13425.1 KFM09923.1 - 3.3 7.6 11.6 7.2 6.5 8.0 1.6 1 1 0 1 1 1 0 O-antigen ligase like membrane protein MARVEL PF01284.18 KFM09924.1 - 0.00015 21.5 16.4 0.00044 20.0 11.2 1.9 1 1 0 1 1 1 1 Membrane-associating domain Tmemb_185A PF10269.4 KFM09924.1 - 0.26 10.8 11.6 0.35 10.4 8.0 1.4 1 1 0 1 1 1 0 Transmembrane Fragile-X-F protein EmrE PF13536.1 KFM09924.1 - 0.52 10.5 12.7 0.31 11.2 5.8 2.2 1 1 1 2 2 2 0 Multidrug resistance efflux transporter EamA PF00892.15 KFM09924.1 - 0.64 10.0 10.7 0.83 9.7 7.4 1.2 1 0 0 1 1 1 0 EamA-like transporter family Ndc1_Nup PF09531.5 KFM09924.1 - 0.69 8.2 3.3 0.89 7.9 2.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FA_desaturase PF00487.19 KFM09924.1 - 1.7 8.0 4.8 1.9 7.8 3.3 1.1 1 0 0 1 1 1 0 Fatty acid desaturase NnrU PF07298.6 KFM09924.1 - 2.4 7.4 7.7 1.4 8.2 2.8 1.8 1 1 1 2 2 2 0 NnrU protein DUF543 PF04418.7 KFM09924.1 - 2.8 7.9 4.7 0.89 9.5 1.1 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF543) 2TM PF13239.1 KFM09924.1 - 7.8 6.6 9.9 65 3.6 6.9 2.2 1 1 0 1 1 1 0 2TM domain dNK PF01712.14 KFM09925.1 - 2.2e-26 92.5 1.0 2.4e-26 92.3 0.7 1.0 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.1 KFM09925.1 - 9.6e-05 22.6 0.2 0.00016 21.9 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFM09925.1 - 0.001 18.9 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 KFM09925.1 - 0.0019 17.6 0.1 0.0028 17.0 0.0 1.2 1 1 0 1 1 1 1 Thymidylate kinase ERGIC_N PF13850.1 KFM09926.1 - 0.11 12.5 0.2 0.25 11.3 0.1 1.7 2 0 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF3915 PF13054.1 KFM09926.1 - 1.8 8.5 4.4 6 6.8 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3915) Cadherin PF00028.12 KFM09928.1 - 6.5e-69 228.2 10.1 4.1e-19 68.6 0.5 5.3 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.12 KFM09928.1 - 1.2e-45 155.2 0.4 2.1e-45 154.3 0.3 1.4 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_pro PF08758.6 KFM09928.1 - 0.012 15.3 0.2 2.6 7.9 0.0 3.0 2 0 0 2 2 2 0 Cadherin prodomain like Rifin_STEVOR PF02009.11 KFM09928.1 - 0.046 13.3 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 Rifin/stevor family Dynamitin PF04912.9 KFM09932.1 - 1.2e-41 142.8 0.3 1.3e-41 142.7 0.2 1.0 1 0 0 1 1 1 1 Dynamitin HalX PF08663.5 KFM09932.1 - 0.0069 16.3 1.1 3.4 7.7 0.0 2.3 2 0 0 2 2 2 2 HalX domain DUF3086 PF11285.3 KFM09932.1 - 0.02 13.7 0.2 0.02 13.7 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3086) GrpE PF01025.14 KFM09932.1 - 0.02 14.4 3.5 0.025 14.1 0.6 2.0 2 0 0 2 2 2 0 GrpE HALZ PF02183.13 KFM09932.1 - 0.082 12.6 1.0 0.082 12.6 0.7 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper HTH_20 PF12840.2 KFM09932.1 - 0.12 12.2 1.7 0.35 10.7 0.1 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain MbeD_MobD PF04899.7 KFM09932.1 - 0.24 11.3 7.7 0.29 11.0 2.1 2.3 2 0 0 2 2 2 0 MbeD/MobD like DASH_Dad3 PF08656.5 KFM09932.1 - 0.37 10.5 2.3 0.53 10.0 0.6 2.0 2 1 0 2 2 2 0 DASH complex subunit Dad3 Occludin_ELL PF07303.8 KFM09932.1 - 0.51 11.1 2.7 2 9.1 0.6 2.2 2 0 0 2 2 2 0 Occludin homology domain Mnd1 PF03962.10 KFM09932.1 - 0.6 9.7 4.9 0.7 9.5 1.0 2.0 2 0 0 2 2 2 0 Mnd1 family TBPIP PF07106.8 KFM09932.1 - 0.61 9.6 3.3 1.6 8.2 0.9 2.0 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DivIC PF04977.10 KFM09932.1 - 0.65 9.5 7.3 16 5.0 0.0 2.6 2 1 1 3 3 3 0 Septum formation initiator GreA_GreB_N PF03449.10 KFM09932.1 - 0.66 10.0 5.7 3 7.9 0.7 2.4 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal SlyX PF04102.7 KFM09932.1 - 0.95 9.8 9.8 0.81 10.1 1.3 3.1 3 0 0 3 3 3 0 SlyX FlaC_arch PF05377.6 KFM09932.1 - 1.6 8.6 5.1 19 5.2 0.8 2.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) SH2 PF00017.19 KFM09933.1 - 2.2e-15 56.1 0.2 3.3e-15 55.6 0.1 1.3 1 0 0 1 1 1 1 SH2 domain EF-hand_1 PF00036.27 KFM09935.1 - 2.9e-16 57.4 4.8 1.6e-06 26.9 0.0 3.9 3 1 1 4 4 4 3 EF hand EF-hand_6 PF13405.1 KFM09935.1 - 4.8e-15 54.0 3.4 6.3e-06 25.6 0.0 3.7 3 1 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.1 KFM09935.1 - 4.4e-14 52.3 2.1 8.5e-13 48.2 0.2 2.7 2 1 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.1 KFM09935.1 - 3.3e-11 41.9 7.6 1.8e-05 23.8 0.1 4.0 4 1 1 5 5 5 3 EF hand EF-hand_8 PF13833.1 KFM09935.1 - 3.5e-10 39.3 2.7 7.6e-08 31.8 0.2 2.3 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFM09935.1 - 9.3e-06 25.6 0.0 1.4e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFM09935.1 - 0.021 14.5 3.5 1.4 8.6 0.1 3.0 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand VWC PF00093.13 KFM09936.1 - 3e-12 46.4 51.0 9.2e-10 38.4 11.4 3.1 3 0 0 3 3 3 3 von Willebrand factor type C domain Pacifastin_I PF05375.8 KFM09936.1 - 3.4e-05 23.2 4.1 3.4e-05 23.2 2.9 4.3 4 1 0 4 4 4 2 Pacifastin inhibitor (LCMII) Sp38 PF07354.7 KFM09937.1 - 2.1e-114 380.7 4.8 2.4e-114 380.5 3.4 1.0 1 0 0 1 1 1 1 Zona-pellucida-binding protein (Sp38) DUF3573 PF12097.3 KFM09937.1 - 0.16 10.5 0.0 0.21 10.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) zf-H2C2_2 PF13465.1 KFM09939.1 - 9e-23 79.3 33.9 2.7e-07 30.5 0.1 6.4 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.21 KFM09939.1 - 2.8e-16 58.7 45.3 1.6e-05 24.9 0.3 6.5 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM09939.1 - 2.7e-08 33.5 43.6 0.00035 20.6 0.2 6.4 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM09939.1 - 0.00047 20.2 27.2 0.18 11.9 0.0 6.0 5 1 1 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFM09939.1 - 0.014 15.2 35.0 0.048 13.5 2.6 6.7 6 1 0 6 6 6 0 C2H2-type zinc finger GAGA PF09237.6 KFM09939.1 - 0.068 12.7 0.1 0.068 12.7 0.1 2.4 1 1 1 2 2 2 0 GAGA factor zf-met PF12874.2 KFM09939.1 - 0.069 13.3 27.6 0.12 12.6 0.1 6.1 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 KFM09939.1 - 1.7 9.0 33.0 0.23 11.7 1.6 5.8 5 0 0 5 5 5 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.2 KFM09939.1 - 4.5 7.4 27.0 5.6 7.1 1.7 5.0 2 2 3 5 5 5 0 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.7 KFM09939.1 - 5.1 6.8 10.2 3.6 7.3 0.6 3.2 3 0 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) AAA PF00004.24 KFM09940.1 - 9.8e-38 129.3 0.0 1.7e-37 128.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 KFM09940.1 - 2e-06 27.5 0.0 7e-06 25.8 0.0 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.7 KFM09940.1 - 1.2e-05 24.5 0.0 2.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KFM09940.1 - 0.0015 18.3 0.1 0.0065 16.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KFM09940.1 - 0.0016 18.5 0.6 0.15 12.2 0.4 2.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KFM09940.1 - 0.0022 17.9 0.0 0.0047 16.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_11 PF13086.1 KFM09940.1 - 0.0048 16.5 0.1 0.028 13.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFM09940.1 - 0.013 15.4 1.0 0.14 12.1 0.7 2.2 1 1 0 1 1 1 0 AAA ATPase domain TIP49 PF06068.8 KFM09940.1 - 0.022 13.4 0.0 0.054 12.2 0.0 1.6 1 0 0 1 1 1 0 TIP49 C-terminus IstB_IS21 PF01695.12 KFM09940.1 - 0.043 13.2 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 KFM09940.1 - 0.065 12.6 0.9 3.9 6.8 0.2 2.4 1 1 1 2 2 2 0 AAA domain AAA_19 PF13245.1 KFM09940.1 - 0.083 12.6 1.2 0.24 11.1 0.3 2.0 2 0 0 2 2 2 0 Part of AAA domain Mg_chelatase PF01078.16 KFM09940.1 - 0.12 11.4 0.1 0.29 10.2 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 KFM09940.1 - 0.13 12.1 0.7 1.4 8.8 0.1 2.5 2 1 0 2 2 2 0 AAA domain Pyridoxal_deC PF00282.14 KFM09941.1 - 8.5e-166 550.9 0.0 1e-165 550.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 KFM09941.1 - 0.0015 17.7 0.0 0.003 16.7 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 KFM09941.1 - 0.041 12.8 0.1 0.19 10.6 0.0 1.8 2 0 0 2 2 2 0 Aminotransferase class I and II BPS PF08947.5 KFM09942.1 - 4.9e-30 102.8 0.6 9.1e-30 102.0 0.4 1.5 1 0 0 1 1 1 1 BPS (Between PH and SH2) SH2 PF00017.19 KFM09942.1 - 1e-15 57.2 0.0 2.2e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 SH2 domain RA PF00788.18 KFM09942.1 - 7.4e-12 45.5 0.2 3.3e-11 43.5 0.1 2.1 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain PH PF00169.24 KFM09942.1 - 3.6e-09 36.7 0.1 8.6e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 KFM09942.1 - 0.046 13.8 0.0 0.13 12.3 0.0 1.8 1 1 0 1 1 1 0 Pleckstrin homology domain WH2 PF02205.15 KFM09943.1 - 2.4e-15 55.5 3.8 0.001 18.6 0.1 3.6 3 0 0 3 3 3 3 WH2 motif Cobl PF09469.5 KFM09944.1 - 1.1e-30 105.3 1.0 3e-30 103.9 0.2 2.2 2 0 0 2 2 2 1 Cordon-bleu ubiquitin-like domain RBD PF02196.10 KFM09944.1 - 0.00054 19.6 0.1 0.033 13.9 0.0 2.5 2 0 0 2 2 2 1 Raf-like Ras-binding domain Rad60-SLD PF11976.3 KFM09944.1 - 0.00082 19.0 0.0 0.0017 17.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TUG-UBL1 PF11470.3 KFM09944.1 - 0.0017 18.1 0.2 0.041 13.8 0.0 2.3 2 0 0 2 2 2 1 GLUT4 regulating protein TUG E1_dh PF00676.15 KFM09945.1 - 4.5e-83 278.4 0.1 7.6e-83 277.6 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.19 KFM09945.1 - 4e-67 225.1 0.0 6.1e-67 224.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Carn_acyltransf PF00755.15 KFM09946.1 - 1.4e-214 713.5 0.0 1.6e-214 713.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase 7tm_1 PF00001.16 KFM09947.1 - 3e-23 82.3 12.4 7.4e-22 77.7 8.6 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 KFM09947.1 - 0.033 13.3 11.8 0.068 12.2 2.7 2.7 3 1 0 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.4 KFM09947.1 - 0.12 11.4 6.7 0.24 10.5 4.7 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx LRR_8 PF13855.1 KFM09948.1 - 9.8e-29 98.9 4.9 7.8e-11 41.5 0.3 2.8 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 KFM09948.1 - 1.2e-15 56.6 13.2 1.8e-06 27.4 0.6 3.3 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM09948.1 - 2e-11 42.2 1.3 0.054 13.5 0.0 4.8 4 0 0 4 4 4 3 Leucine Rich Repeat I-set PF07679.11 KFM09948.1 - 5.9e-11 42.0 0.0 8.8e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_7 PF13504.1 KFM09948.1 - 6.5e-08 31.5 7.9 0.062 13.5 0.3 4.8 4 0 0 4 4 4 3 Leucine rich repeat Ig_2 PF13895.1 KFM09948.1 - 7.2e-06 26.0 0.0 1.4e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFM09948.1 - 0.00025 21.1 0.0 0.00068 19.7 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin domain LRR_6 PF13516.1 KFM09948.1 - 0.00054 19.7 4.3 0.77 10.0 0.1 4.1 4 0 0 4 4 4 1 Leucine Rich repeat Ig_3 PF13927.1 KFM09948.1 - 0.00071 20.0 0.1 0.0019 18.6 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain Cadherin PF00028.12 KFM09949.1 - 2e-70 233.0 4.8 2.6e-16 59.6 0.0 6.4 6 0 0 6 6 6 6 Cadherin domain Bax1-I PF01027.15 KFM09950.1 - 3.9e-41 140.9 14.0 3.9e-41 140.9 9.7 1.4 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.2 KFM09950.1 - 3.6e-15 55.8 10.0 3e-11 43.0 0.7 3.3 2 1 1 3 3 3 3 Bax inhibitor 1 like V-set PF07686.12 KFM09951.1 - 1.2e-19 70.3 0.6 4.9e-15 55.4 0.0 3.1 2 1 0 2 2 2 2 Immunoglobulin V-set domain I-set PF07679.11 KFM09951.1 - 1.2e-17 63.5 0.1 1.1e-08 34.7 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM09951.1 - 3.9e-15 55.7 1.3 9.8e-10 38.4 0.1 2.9 2 1 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 KFM09951.1 - 1.9e-13 50.7 0.7 8.7e-08 32.5 0.2 3.2 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 KFM09951.1 - 6.5e-11 42.2 0.2 1.7e-05 24.8 0.0 3.2 2 1 0 2 2 2 2 Immunoglobulin domain Syndecan PF01034.15 KFM09951.1 - 0.0017 17.9 0.1 0.0063 16.1 0.0 1.9 2 0 0 2 2 2 1 Syndecan domain Adeno_E3_CR2 PF02439.10 KFM09951.1 - 0.0031 16.9 0.3 0.0062 16.0 0.2 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 V-set_CD47 PF08204.6 KFM09951.1 - 0.0056 16.4 0.0 0.5 10.1 0.0 2.5 2 1 0 2 2 2 1 CD47 immunoglobulin-like domain Sp38 PF07354.7 KFM09951.1 - 0.011 14.3 0.0 0.022 13.4 0.0 1.4 1 0 0 1 1 1 0 Zona-pellucida-binding protein (Sp38) EphA2_TM PF14575.1 KFM09951.1 - 0.019 15.3 0.0 0.036 14.4 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain C2-set PF05790.10 KFM09951.1 - 0.075 13.0 0.6 1.8 8.6 0.0 2.8 3 0 0 3 3 3 0 Immunoglobulin C2-set domain DUF2207 PF09972.4 KFM09951.1 - 0.12 10.8 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) FixQ PF05545.6 KFM09951.1 - 0.14 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ EURL PF06937.6 KFM09952.1 - 1.7e-152 506.7 5.6 1.9e-152 506.6 3.9 1.0 1 0 0 1 1 1 1 EURL protein FEZ PF07763.8 KFM09952.1 - 0.00071 19.3 0.8 0.0012 18.6 0.5 1.3 1 0 0 1 1 1 1 FEZ-like protein TALPID3 PF15324.1 KFM09952.1 - 0.018 12.4 1.2 0.022 12.1 0.8 1.0 1 0 0 1 1 1 0 Hedgehog signalling target zf-CCHC_2 PF13696.1 KFM09952.1 - 0.044 13.2 4.9 0.25 10.8 0.1 2.5 2 0 0 2 2 2 0 Zinc knuckle RecR PF02132.10 KFM09952.1 - 1.2 8.6 5.6 15 5.1 0.1 2.7 1 1 1 2 2 2 0 RecR protein Lectin_C PF00059.16 KFM09953.1 - 2.1e-13 50.8 1.2 3e-13 50.3 0.2 1.8 2 0 0 2 2 2 1 Lectin C-type domain Trypsin PF00089.21 KFM09954.1 - 2.1e-40 138.6 0.1 2.3e-40 138.5 0.0 1.0 1 0 0 1 1 1 1 Trypsin I-set PF07679.11 KFM09955.1 - 5.3e-83 272.9 1.0 4.3e-20 71.3 0.0 5.6 5 0 0 5 5 5 5 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM09955.1 - 8.5e-50 166.8 0.2 1.3e-11 44.4 0.0 5.3 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.20 KFM09955.1 - 2.8e-40 136.2 0.2 1.2e-07 31.7 0.0 6.2 6 1 0 6 6 6 5 Immunoglobulin domain Ig_3 PF13927.1 KFM09955.1 - 2.4e-35 120.7 3.3 6.3e-07 29.8 0.0 5.9 5 0 0 5 5 5 5 Immunoglobulin domain V-set PF07686.12 KFM09955.1 - 1.4e-30 105.5 0.8 2.9e-05 23.9 0.0 6.2 5 1 0 5 5 5 5 Immunoglobulin V-set domain fn3 PF00041.16 KFM09955.1 - 1.3e-29 102.1 1.2 4.7e-16 58.6 0.2 2.8 2 0 0 2 2 2 2 Fibronectin type III domain C2-set_2 PF08205.7 KFM09955.1 - 2.5e-11 43.3 1.0 0.0029 17.4 0.0 5.3 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.11 KFM09955.1 - 1.2e-06 27.1 0.4 0.049 11.8 0.0 3.8 1 1 2 4 4 4 3 Alphaherpesvirus glycoprotein E Receptor_2B4 PF11465.3 KFM09955.1 - 5.9e-05 22.9 0.7 12 5.8 0.0 5.3 5 1 0 5 5 5 1 Natural killer cell receptor 2B4 C1-set PF07654.10 KFM09955.1 - 0.00024 21.0 0.1 2.1 8.4 0.0 3.9 4 0 0 4 4 4 2 Immunoglobulin C1-set domain Interfer-bind PF09294.5 KFM09955.1 - 0.0016 18.4 0.3 0.42 10.6 0.0 3.1 3 0 0 3 3 3 1 Interferon-alpha/beta receptor, fibronectin type III C2-set PF05790.10 KFM09955.1 - 0.005 16.7 0.3 3.4 7.6 0.0 4.6 5 0 0 5 5 5 1 Immunoglobulin C2-set domain DUF2469 PF10611.4 KFM09957.1 - 0.00018 21.7 0.2 0.0012 19.1 0.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF2469) TGS PF02824.16 KFM09957.1 - 0.00031 20.5 0.0 0.00093 18.9 0.0 1.8 2 0 0 2 2 2 1 TGS domain IL6 PF00489.12 KFM09957.1 - 0.046 13.3 0.0 0.093 12.3 0.0 1.5 1 0 0 1 1 1 0 Interleukin-6/G-CSF/MGF family tRNA_SAD PF07973.9 KFM09957.1 - 0.077 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Threonyl and Alanyl tRNA synthetase second additional domain I-set PF07679.11 KFM09958.1 - 7e-17 61.0 0.2 3.4e-10 39.6 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.12 KFM09958.1 - 1e-15 57.5 5.2 3.2e-07 30.2 0.0 2.6 3 1 0 3 3 3 2 Immunoglobulin V-set domain ig PF00047.20 KFM09958.1 - 2.2e-15 56.4 0.9 5.5e-08 32.8 0.1 2.8 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.1 KFM09958.1 - 5.7e-15 55.2 2.7 4.1e-10 39.6 0.4 2.3 1 1 1 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 KFM09958.1 - 7.5e-11 42.3 4.6 4.5e-05 23.8 1.4 3.8 2 2 0 2 2 2 2 Immunoglobulin domain Herpes_gE PF02480.11 KFM09958.1 - 7.3e-05 21.2 1.2 0.058 11.6 0.0 2.9 1 1 2 3 3 3 2 Alphaherpesvirus glycoprotein E C2-set_2 PF08205.7 KFM09958.1 - 0.0021 17.8 0.2 0.0045 16.8 0.1 1.6 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain DUF4307 PF14155.1 KFM09958.1 - 0.0036 17.0 0.8 2.7 7.7 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4307) TMEM171 PF15471.1 KFM09958.1 - 0.052 12.3 0.0 0.084 11.6 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 ATP-synt_F6 PF05511.6 KFM09959.1 - 1.1e-38 131.1 0.0 1.2e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 GABP-alpha PF11620.3 KFM09960.1 - 1.4e-41 140.3 1.0 3e-41 139.3 0.7 1.6 1 0 0 1 1 1 1 GA-binding protein alpha chain Ets PF00178.17 KFM09960.1 - 3.1e-39 132.9 0.5 3.1e-39 132.9 0.3 1.8 2 0 0 2 2 2 1 Ets-domain SAM_PNT PF02198.11 KFM09960.1 - 2.1e-28 97.8 0.1 6.3e-28 96.3 0.1 1.9 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Syntaxin-18_N PF10496.4 KFM09960.1 - 0.018 14.8 0.1 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus APP_E2 PF12925.2 KFM09961.1 - 1.2e-76 256.6 18.9 2.1e-76 255.8 13.1 1.4 1 0 0 1 1 1 1 E2 domain of amyloid precursor protein APP_N PF02177.11 KFM09961.1 - 2e-43 146.4 0.3 6.8e-43 144.7 0.2 2.0 1 0 0 1 1 1 1 Amyloid A4 N-terminal heparin-binding APP_amyloid PF10515.4 KFM09961.1 - 6e-29 100.0 0.5 1.9e-28 98.4 0.3 2.0 1 0 0 1 1 1 1 beta-amyloid precursor protein C-terminus Beta-APP PF03494.8 KFM09961.1 - 2.7e-28 97.1 3.2 5.1e-28 96.2 2.2 1.5 1 0 0 1 1 1 1 Beta-amyloid peptide (beta-APP) APP_Cu_bd PF12924.2 KFM09961.1 - 3.3e-28 97.9 4.6 3.3e-28 97.9 3.2 2.2 2 0 0 2 2 2 1 Copper-binding of amyloid precursor, CuBD Kunitz_BPTI PF00014.18 KFM09961.1 - 2.8e-19 69.0 6.0 5.6e-19 68.0 4.2 1.5 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Exonuc_VII_L PF02601.10 KFM09961.1 - 0.077 12.1 11.4 0.11 11.6 7.5 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit Activator-TraM PF11657.3 KFM09961.1 - 0.091 12.2 5.6 0.32 10.4 3.8 1.8 1 0 0 1 1 1 0 Transcriptional activator TraM DUF2668 PF10873.3 KFM09962.1 - 3.4e-53 179.9 17.2 3.6e-53 179.8 11.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2668) DUF1049 PF06305.6 KFM09962.1 - 0.28 10.6 1.2 0.36 10.3 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Tic20 PF09685.5 KFM09962.1 - 0.34 10.9 3.0 0.41 10.6 2.1 1.1 1 0 0 1 1 1 0 Tic20-like protein PepSY_TM_3 PF13706.1 KFM09962.1 - 8.2 5.9 6.1 10 5.5 3.8 1.5 1 1 1 2 2 2 0 PepSY-associated TM helix Atracotoxin PF05353.6 KFM09963.1 - 0.053 13.3 10.2 0.092 12.5 7.0 1.5 1 0 0 1 1 1 0 Delta Atracotoxin ADAM_spacer1 PF05986.9 KFM09964.1 - 8.8e-33 112.5 0.1 1.3e-32 111.9 0.1 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Reprolysin PF01421.14 KFM09964.1 - 3.9e-22 78.8 0.2 6.8e-22 78.0 0.2 1.4 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_3 PF13582.1 KFM09964.1 - 8.9e-13 48.8 1.0 8.9e-13 48.8 0.7 1.9 2 0 0 2 2 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KFM09964.1 - 1.1e-09 38.4 0.9 2.5e-09 37.3 0.6 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 TSP_1 PF00090.14 KFM09964.1 - 1.4e-09 37.9 19.7 8.2e-09 35.4 3.7 4.3 4 0 0 4 4 3 2 Thrombospondin type 1 domain Reprolysin_2 PF13574.1 KFM09964.1 - 1.4e-09 38.2 0.5 1.4e-09 38.2 0.3 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFM09964.1 - 5.9e-08 32.4 1.1 1e-07 31.7 0.7 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KFM09964.1 - 0.00019 21.1 0.8 0.00039 20.1 0.5 1.5 1 0 0 1 1 1 1 Matrixin DUF3285 PF11688.3 KFM09964.1 - 0.05 13.2 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3285) Peptidase_M54 PF07998.6 KFM09964.1 - 0.072 12.8 0.1 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M54 Toprim_Crpt PF13342.1 KFM09964.1 - 0.1 12.2 0.1 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 C-terminal repeat of topoisomerase DUF955 PF06114.8 KFM09964.1 - 0.11 12.2 0.1 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF955) DUF1025 PF06262.6 KFM09964.1 - 0.14 11.9 0.5 0.29 10.9 0.4 1.5 1 0 0 1 1 1 0 Possibl zinc metallo-peptidase Methyltransf_26 PF13659.1 KFM09968.1 - 5e-14 52.3 0.0 6.6e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFM09968.1 - 2.5e-09 36.7 0.0 3.2e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 KFM09968.1 - 1.8e-05 24.3 0.0 3.2e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KFM09968.1 - 0.00012 21.3 0.0 0.00087 18.4 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 KFM09968.1 - 0.024 15.0 0.0 0.033 14.5 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KFM09968.1 - 0.033 14.6 0.0 0.087 13.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.4 KFM09968.1 - 0.042 13.2 0.1 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_24 PF13578.1 KFM09968.1 - 0.056 14.2 0.0 0.1 13.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KFM09968.1 - 0.086 13.4 0.0 0.15 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF1115 PF06544.7 KFM09969.1 - 1.2e-31 109.0 0.1 1.9e-31 108.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) RWD PF05773.17 KFM09969.1 - 1.7e-13 50.4 0.4 3e-13 49.6 0.3 1.4 1 0 0 1 1 1 1 RWD domain Pox_F15 PF04596.7 KFM09969.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Poxvirus protein F15 UCH PF00443.24 KFM09970.1 - 4.4e-51 173.5 19.4 2.1e-50 171.3 13.5 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KFM09970.1 - 1.4e-21 76.3 9.2 5.6e-21 74.4 6.4 2.1 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 KFM09970.1 - 1.5e-15 57.4 27.2 3.1e-15 56.3 13.9 3.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Cpn60_TCP1 PF00118.19 KFM09971.1 - 8.5e-139 463.2 4.6 9.8e-139 463.0 3.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family APG6 PF04111.7 KFM09972.1 - 0.0013 17.9 9.5 0.0015 17.6 6.6 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 GAS PF13851.1 KFM09972.1 - 0.032 13.4 14.9 0.047 12.8 10.3 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4559 PF15112.1 KFM09972.1 - 0.065 12.3 4.8 0.083 12.0 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) KIX PF02172.11 KFM09972.1 - 0.067 13.2 2.2 0.12 12.4 1.4 1.6 1 1 0 1 1 1 0 KIX domain CCDC-167 PF15188.1 KFM09972.1 - 0.067 13.1 9.4 0.12 12.3 6.5 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Ax_dynein_light PF10211.4 KFM09972.1 - 0.073 12.8 10.6 0.1 12.4 7.4 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain Occludin_ELL PF07303.8 KFM09972.1 - 0.15 12.7 8.8 0.62 10.8 0.9 2.0 1 1 1 2 2 2 0 Occludin homology domain DUF1843 PF08898.5 KFM09972.1 - 0.17 11.9 0.4 0.17 11.9 0.3 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1843) Mnd1 PF03962.10 KFM09972.1 - 0.28 10.8 8.5 0.39 10.3 5.9 1.2 1 0 0 1 1 1 0 Mnd1 family Spc24 PF08286.6 KFM09972.1 - 0.33 10.6 8.1 0.2 11.3 3.7 1.9 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 V_ATPase_I PF01496.14 KFM09972.1 - 0.44 8.3 4.2 0.45 8.3 2.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4613 PF15390.1 KFM09972.1 - 0.5 8.4 5.9 0.53 8.4 4.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Nup88 PF10168.4 KFM09972.1 - 0.57 7.9 8.8 0.66 7.7 6.1 1.0 1 0 0 1 1 1 0 Nuclear pore component DUF972 PF06156.8 KFM09972.1 - 0.79 10.0 11.2 0.87 9.9 3.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Fmp27_WPPW PF10359.4 KFM09972.1 - 0.94 7.8 8.5 1.1 7.5 5.9 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Seryl_tRNA_N PF02403.17 KFM09972.1 - 1.1 9.2 9.3 1.9 8.5 6.4 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Cdc6_C PF09079.6 KFM09972.1 - 1.2 8.9 4.4 2 8.1 0.5 2.2 2 0 0 2 2 2 0 CDC6, C terminal TMPIT PF07851.8 KFM09972.1 - 2.2 7.2 7.1 2.8 6.9 4.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein Takusan PF04822.8 KFM09972.1 - 2.2 8.0 8.3 4.5 7.1 5.8 1.6 1 1 0 1 1 1 0 Takusan DivIVA PF05103.8 KFM09972.1 - 2.6 8.1 12.2 7.5 6.6 1.2 2.2 1 1 1 2 2 2 0 DivIVA protein CENP-H PF05837.7 KFM09972.1 - 3.3 7.9 11.6 25 5.0 7.9 2.1 1 1 0 1 1 1 0 Centromere protein H (CENP-H) YlqD PF11068.3 KFM09972.1 - 5.3 7.0 13.1 0.38 10.7 2.0 2.2 1 1 1 2 2 2 0 YlqD protein DUF342 PF03961.8 KFM09972.1 - 5.9 5.1 7.7 7.6 4.8 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) bZIP_2 PF07716.10 KFM09972.1 - 7.2 6.5 14.4 6.4 6.6 1.7 2.5 2 0 0 2 2 2 0 Basic region leucine zipper TSC22 PF01166.13 KFM09972.1 - 8.1 6.4 15.6 2.7 8.0 1.6 2.5 1 1 1 2 2 2 0 TSC-22/dip/bun family BTB PF00651.26 KFM09973.1 - 5.2e-24 84.3 2.0 5.4e-24 84.3 0.4 1.8 2 0 0 2 2 2 1 BTB/POZ domain bZIP_Maf PF03131.12 KFM09973.1 - 6.8e-16 58.3 5.6 1.9e-15 56.9 3.9 1.8 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.16 KFM09973.1 - 1.6e-10 40.7 7.9 3.7e-10 39.6 5.5 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFM09973.1 - 2.8e-07 30.2 8.8 6.2e-07 29.1 6.1 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Med4 PF10018.4 KFM09973.1 - 0.0062 15.9 0.3 0.016 14.6 0.2 1.7 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 ANF_receptor PF01094.23 KFM09974.1 - 3e-66 223.5 0.0 5.1e-66 222.8 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.21 KFM09974.1 - 1e-53 181.0 0.1 1.6e-53 180.4 0.1 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.4 KFM09974.1 - 2.1e-28 98.0 1.5 9.2e-28 96.0 0.4 2.5 3 0 0 3 3 3 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.15 KFM09974.1 - 3.8e-21 75.3 0.0 6.8e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.1 KFM09974.1 - 1.9e-07 30.7 0.0 3.6e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein PGM_PMM_II PF02879.11 KFM09974.1 - 0.15 12.3 0.0 0.56 10.5 0.0 1.9 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II RhoGEF PF00621.15 KFM09976.1 - 5.4e-43 146.9 2.0 5.4e-43 146.9 1.4 2.2 3 0 0 3 3 3 1 RhoGEF domain PH PF00169.24 KFM09976.1 - 2.3e-21 75.9 1.3 1.3e-11 44.5 0.1 3.1 3 0 0 3 3 3 2 PH domain RBD PF02196.10 KFM09976.1 - 2.5e-19 68.7 0.0 9.5e-19 66.9 0.0 2.1 2 0 0 2 2 2 1 Raf-like Ras-binding domain PH_9 PF15410.1 KFM09976.1 - 5.3e-11 42.7 0.3 1.5e-10 41.2 0.2 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PDZ PF00595.19 KFM09976.1 - 7e-08 32.5 0.0 1.9e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM09976.1 - 9e-05 22.2 0.0 0.00027 20.7 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PH_11 PF15413.1 KFM09976.1 - 0.0086 16.3 0.7 0.21 11.8 0.5 3.2 2 1 0 2 2 2 1 Pleckstrin homology domain Sod_Cu PF00080.15 KFM09977.1 - 4.1e-44 150.1 4.9 4.5e-44 150.0 3.4 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Pkinase PF00069.20 KFM09978.1 - 3.3e-63 213.2 0.0 5.7e-63 212.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM09978.1 - 1.7e-34 119.1 0.0 2.6e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM09978.1 - 6.8e-11 41.6 0.0 1.3e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFM09978.1 - 5.5e-06 25.6 0.1 1e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFM09978.1 - 6.1e-05 22.4 0.7 0.00015 21.1 0.3 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 KFM09978.1 - 0.00016 21.5 0.0 0.00031 20.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KFM09978.1 - 0.049 12.9 0.2 0.1 11.9 0.1 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Npa1 PF11707.3 KFM09979.1 - 2e-79 266.9 14.7 3.1e-79 266.3 0.5 4.3 3 0 0 3 3 3 3 Ribosome 60S biogenesis N-terminal FAM176 PF14851.1 KFM09980.1 - 6.1e-41 139.6 0.0 6.1e-41 139.6 0.0 1.6 2 0 0 2 2 2 1 FAM176 family Gal_Lectin PF02140.13 KFM09980.1 - 9.8e-36 121.9 7.9 2.6e-17 62.8 0.6 2.3 2 0 0 2 2 2 2 Galactose binding lectin domain DUF4366 PF14283.1 KFM09980.1 - 0.073 12.4 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF2870 PF11069.3 KFM09981.1 - 8.2e-46 154.0 1.7 8.2e-46 154.0 1.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2870) ubiquitin PF00240.18 KFM09981.1 - 0.028 13.8 1.4 0.25 10.7 0.0 2.8 3 0 0 3 3 3 0 Ubiquitin family Flavi_glycop_C PF02832.11 KFM09981.1 - 0.1 12.5 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Flavivirus glycoprotein, immunoglobulin-like domain DUF2857 PF11198.3 KFM09981.1 - 0.17 11.3 1.8 4.2 6.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2857) Syja_N PF02383.13 KFM09982.1 - 7.5e-81 271.3 0.1 1.3e-80 270.5 0.1 1.4 1 0 0 1 1 1 1 SacI homology domain DUF1866 PF08952.6 KFM09982.1 - 8.3e-56 187.5 0.2 7.7e-55 184.4 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1866) Exo_endo_phos PF03372.18 KFM09982.1 - 1.8e-27 96.8 0.5 3.8e-27 95.8 0.4 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RRM_5 PF13893.1 KFM09982.1 - 0.078 12.8 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GCFC PF07842.7 KFM09983.1 - 2.3e-35 122.3 0.4 6.2e-35 120.8 0.3 1.7 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein BLOC1_2 PF10046.4 KFM09983.1 - 0.16 12.0 5.0 0.19 11.8 0.3 3.2 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4571 PF15137.1 KFM09984.1 - 1.4e-90 302.5 5.3 1.6e-90 302.3 3.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4571) Interfer-bind PF09294.5 KFM09985.1 - 5.9e-24 84.1 0.2 7.6e-24 83.7 0.1 1.2 1 0 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III Interfer-bind PF09294.5 KFM09986.1 - 7.6e-28 96.6 0.3 1.2e-27 95.9 0.0 1.5 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.16 KFM09986.1 - 0.00013 22.0 0.1 0.00036 20.6 0.1 1.7 2 0 0 2 2 2 1 Fibronectin type III domain Interfer-bind PF09294.5 KFM09987.1 - 3.3e-46 155.7 3.1 2.4e-22 78.9 0.2 3.5 4 0 0 4 4 4 2 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.12 KFM09987.1 - 6.2e-34 115.9 15.4 8.3e-19 67.3 1.7 3.7 3 0 0 3 3 3 2 Tissue factor fn3 PF00041.16 KFM09987.1 - 8.1e-08 32.2 8.7 0.00043 20.3 0.0 4.6 4 1 0 4 4 4 3 Fibronectin type III domain Tissue_fac PF01108.12 KFM09989.1 - 3.1e-21 75.1 1.0 4.6e-21 74.5 0.1 1.7 2 0 0 2 2 2 1 Tissue factor Interfer-bind PF09294.5 KFM09989.1 - 4.4e-16 58.8 0.4 9.2e-16 57.8 0.3 1.5 1 1 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.16 KFM09989.1 - 1.2e-07 31.7 0.2 1.9e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 Fibronectin type III domain UPF0220 PF05255.6 KFM09990.1 - 1.7e-53 180.3 4.3 1.8e-53 180.1 2.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF1992 PF09350.5 KFM09991.1 - 8.1e-23 80.0 0.0 2e-22 78.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) DnaJ PF00226.26 KFM09991.1 - 2.1e-14 52.9 0.5 6.8e-14 51.3 0.3 2.0 1 0 0 1 1 1 1 DnaJ domain DUF3597 PF12200.3 KFM09991.1 - 0.0048 17.2 0.6 0.0076 16.6 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3597) NIT PF08376.5 KFM09991.1 - 0.14 11.6 0.0 0.14 11.6 0.0 3.0 4 0 0 4 4 4 0 Nitrate and nitrite sensing GARS_A PF01071.14 KFM09992.1 - 7.3e-91 303.0 0.0 1.4e-90 302.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Formyl_trans_N PF00551.14 KFM09992.1 - 2.5e-65 219.4 0.1 6.1e-65 218.1 0.1 1.7 1 0 0 1 1 1 1 Formyl transferase GARS_N PF02844.10 KFM09992.1 - 1.8e-39 134.2 1.9 1.1e-37 128.5 0.1 3.5 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 KFM09992.1 - 2.7e-35 121.6 0.2 2.3e-34 118.6 0.0 2.7 3 0 0 3 3 2 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 KFM09992.1 - 4.3e-31 106.9 0.6 3e-30 104.2 0.1 2.5 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 KFM09992.1 - 4.3e-21 74.9 0.8 1.4e-20 73.2 0.5 2.0 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 KFM09992.1 - 4.6e-13 49.3 0.0 1.4e-12 47.7 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KFM09992.1 - 6.8e-08 31.6 0.0 1.6e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KFM09992.1 - 0.00016 21.0 0.0 0.0005 19.4 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KFM09992.1 - 0.00057 19.7 0.0 0.0017 18.2 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 KFM09992.1 - 0.0024 17.2 0.1 0.0087 15.3 0.1 2.0 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.6 KFM09992.1 - 0.0036 16.7 0.3 0.011 15.2 0.0 2.0 3 0 0 3 3 3 1 RimK-like ATP-grasp domain ATP-grasp_2 PF08442.5 KFM09992.1 - 0.0083 15.5 0.0 0.023 14.0 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain PTS_EIIA_2 PF00359.17 KFM09992.1 - 0.043 13.5 0.1 0.81 9.3 0.0 2.6 3 0 0 3 3 3 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Dala_Dala_lig_C PF07478.8 KFM09992.1 - 0.045 13.1 0.0 0.096 12.0 0.0 1.5 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus DND1_DSRM PF14709.1 KFM09993.1 - 5.6e-19 68.1 0.1 1.7e-18 66.6 0.0 1.9 2 0 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 G-patch PF01585.18 KFM09993.1 - 8.3e-17 60.7 2.9 2e-16 59.5 2.0 1.7 1 0 0 1 1 1 1 G-patch domain dsrm PF00035.20 KFM09993.1 - 2.9e-14 53.4 0.0 8.5e-14 51.8 0.0 1.9 1 0 0 1 1 1 1 Double-stranded RNA binding motif G-patch_2 PF12656.2 KFM09993.1 - 1.2e-06 28.2 2.2 1.9e-06 27.6 0.6 2.0 2 0 0 2 2 2 1 DExH-box splicing factor binding site ADH_zinc_N PF00107.21 KFM09995.1 - 5e-11 42.2 0.0 8.1e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFM09995.1 - 4.8e-06 26.2 0.0 1e-05 25.2 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SH3_9 PF14604.1 KFM09996.1 - 1.1e-71 236.2 10.6 3.8e-17 61.5 0.1 5.5 5 0 0 5 5 5 5 Variant SH3 domain SH3_1 PF00018.23 KFM09996.1 - 1e-64 213.7 14.0 4e-17 61.3 0.2 5.5 5 0 0 5 5 5 5 SH3 domain SH3_2 PF07653.12 KFM09996.1 - 7.4e-58 191.8 2.4 3.2e-14 52.1 0.0 5.5 5 0 0 5 5 5 5 Variant SH3 domain RhoGEF PF00621.15 KFM09996.1 - 1.3e-44 152.2 2.3 1.3e-44 152.2 1.6 2.9 3 1 0 3 3 1 1 RhoGEF domain EF-hand_4 PF12763.2 KFM09996.1 - 5.3e-31 106.4 0.0 8e-15 54.4 0.0 3.1 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand C2 PF00168.25 KFM09996.1 - 3.1e-18 65.3 0.0 1.1e-17 63.6 0.0 2.0 2 0 0 2 2 2 1 C2 domain EF-hand_1 PF00036.27 KFM09996.1 - 1.4e-08 33.4 0.0 0.0034 16.5 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 KFM09996.1 - 2.2e-08 34.1 0.0 0.0013 18.7 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 KFM09996.1 - 3.3e-06 26.5 0.0 0.48 10.4 0.0 4.0 4 0 0 4 4 3 1 EF-hand domain PH PF00169.24 KFM09996.1 - 1.4e-05 25.2 1.7 2.3e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 PH domain EF-hand_5 PF13202.1 KFM09996.1 - 0.0042 16.3 0.2 0.77 9.2 0.0 2.7 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KFM09996.1 - 0.0091 15.5 0.0 0.26 10.9 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair OSCP PF00213.13 KFM09997.1 - 5.9e-45 153.2 0.4 6.6e-45 153.0 0.3 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DUF2630 PF10944.3 KFM09997.1 - 0.075 13.1 0.0 0.19 11.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2630) SSF PF00474.12 KFM09998.1 - 2.4e-162 540.2 23.2 3.2e-162 539.8 16.1 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Ribosomal_S6 PF01250.12 KFM09999.1 - 8.6e-12 44.7 0.0 1.1e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 ISK_Channel PF02060.10 KFM10000.1 - 1.7e-11 43.7 0.1 2e-11 43.5 0.1 1.1 1 0 0 1 1 1 1 Slow voltage-gated potassium channel OSTbeta PF15048.1 KFM10000.1 - 0.014 15.4 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DUF2207 PF09972.4 KFM10000.1 - 0.017 13.6 0.7 0.026 13.1 0.3 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) HsdM_N PF12161.3 KFM10000.1 - 0.033 14.5 0.4 0.075 13.4 0.1 1.7 2 0 0 2 2 2 0 HsdM N-terminal domain FeoB_C PF07664.7 KFM10000.1 - 0.073 12.4 0.5 0.12 11.8 0.4 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B C terminus DUF2762 PF10960.3 KFM10000.1 - 0.075 12.7 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) DUF4014 PF13198.1 KFM10000.1 - 0.076 13.4 0.8 0.11 12.8 0.2 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4014) FAM165 PF14981.1 KFM10001.1 - 4.4e-31 106.1 3.1 4.6e-31 106.0 2.2 1.0 1 0 0 1 1 1 1 FAM165 family DUF2570 PF10828.3 KFM10001.1 - 0.039 13.5 0.0 0.043 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) MadM PF03818.8 KFM10001.1 - 0.13 11.8 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Malonate/sodium symporter MadM subunit ISK_Channel PF02060.10 KFM10002.1 - 1.8e-38 131.0 0.0 2.1e-38 130.7 0.0 1.0 1 0 0 1 1 1 1 Slow voltage-gated potassium channel T2SF PF00482.18 KFM10002.1 - 0.063 13.1 0.4 0.086 12.7 0.2 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F Calcipressin PF04847.7 KFM10003.1 - 4.1e-57 192.7 0.6 4.6e-57 192.5 0.4 1.0 1 0 0 1 1 1 1 Calcipressin GST_N_3 PF13417.1 KFM10004.1 - 1.5e-08 34.7 0.0 3.5e-08 33.5 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFM10004.1 - 9.4e-06 25.4 0.0 1.8e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KFM10004.1 - 3.7e-05 23.6 0.0 8.8e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFM10004.1 - 0.003 17.4 0.3 0.035 14.0 0.1 2.5 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFM10004.1 - 0.008 16.6 0.0 0.013 15.9 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain EntA_Immun PF08951.5 KFM10004.1 - 0.037 14.1 0.3 0.79 9.9 0.2 2.4 2 0 0 2 2 2 0 Enterocin A Immunity Runt PF00853.14 KFM10005.1 - 6.8e-53 177.7 0.2 9.8e-53 177.2 0.1 1.2 1 0 0 1 1 1 1 Runt domain RunxI PF08504.6 KFM10005.1 - 2.7e-42 143.3 5.6 2.7e-42 143.3 3.9 1.8 2 0 0 2 2 2 1 Runx inhibition domain Rubis-subs-bind PF09273.6 KFM10006.1 - 3.3e-21 75.5 1.4 5.3e-21 74.8 0.5 1.7 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding SET PF00856.23 KFM10006.1 - 2e-09 37.9 0.0 4.6e-09 36.7 0.0 1.6 2 0 0 2 2 2 1 SET domain Dna2 PF08696.6 KFM10006.1 - 0.065 12.5 0.3 0.12 11.6 0.2 1.3 1 0 0 1 1 1 0 DNA replication factor Dna2 adh_short PF00106.20 KFM10007.1 - 8e-24 84.4 0.0 1.3e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFM10007.1 - 3.1e-07 30.2 0.0 4.4e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 KFM10007.1 - 5.2e-05 22.2 0.0 7.8e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein HATPase_c PF02518.21 KFM10007.1 - 0.036 13.7 0.0 0.086 12.5 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Dopey_N PF04118.9 KFM10008.1 - 5.5e-104 347.2 0.5 1.3e-103 346.0 0.3 1.6 1 0 0 1 1 1 1 Dopey, N-terminal CAF-1_p60_C PF15512.1 KFM10009.1 - 1.2e-58 198.4 24.8 1.7e-58 198.0 17.2 1.2 1 0 0 1 1 1 1 Chromatin assembly factor complex 1 subunit p60, C-terminal WD40 PF00400.27 KFM10009.1 - 8.3e-35 117.4 11.6 7.2e-09 35.1 0.3 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 KFM10009.1 - 3.8e-06 26.7 1.1 0.00073 19.2 0.1 3.6 4 0 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 KFM10009.1 - 1.8e-05 23.7 0.2 0.021 13.6 0.0 2.6 2 1 0 2 2 2 2 Coatomer WD associated region IKI3 PF04762.7 KFM10009.1 - 0.012 13.5 0.5 0.38 8.5 0.0 2.1 2 0 0 2 2 2 0 IKI3 family PMP22_Claudin PF00822.15 KFM10010.1 - 9.3e-33 113.2 11.5 1.1e-32 112.9 8.0 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFM10010.1 - 5.2e-12 45.7 11.0 6.8e-12 45.4 7.6 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 KFM10010.1 - 0.049 13.2 11.7 0.061 12.9 7.3 1.9 1 1 0 1 1 1 0 Amastin surface glycoprotein YtpI PF14007.1 KFM10010.1 - 0.089 12.7 0.8 2.5 8.1 0.0 2.5 1 1 1 2 2 2 0 YtpI-like protein Hormone_6 PF00236.13 KFM10010.1 - 0.21 11.4 2.1 0.4 10.5 1.5 1.4 1 0 0 1 1 1 0 Glycoprotein hormone PIRT PF15099.1 KFM10010.1 - 1.3 8.2 8.5 0.098 11.8 1.6 2.2 3 0 0 3 3 3 0 Phosphoinositide-interacting protein family DUF4097 PF13349.1 KFM10010.1 - 2.2 7.7 0.0 2.2 7.7 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4097) DUF4064 PF13273.1 KFM10010.1 - 3.4 7.8 11.2 5.3 7.1 0.5 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF4064) Tetraspannin PF00335.15 KFM10010.1 - 6.9 5.8 13.7 0.16 11.1 1.0 2.4 1 1 1 2 2 2 0 Tetraspanin family BPL_LplA_LipB PF03099.14 KFM10011.1 - 7.3e-17 61.5 0.0 1.6e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_N PF09825.4 KFM10011.1 - 5.6e-11 41.8 0.0 1e-05 24.5 0.0 2.4 1 1 0 2 2 2 2 Biotin-protein ligase, N terminal BPL_C PF02237.12 KFM10011.1 - 4.9e-09 35.7 0.0 1.1e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain ABC_transp_aux PF09822.4 KFM10011.1 - 0.0038 16.7 0.0 0.0067 15.9 0.0 1.4 1 0 0 1 1 1 1 ABC-type uncharacterized transport system ThuA PF06283.6 KFM10011.1 - 0.054 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Trehalose utilisation Ripply PF14998.1 KFM10012.1 - 1.1e-23 83.0 0.0 1.2e-23 82.9 0.0 1.0 1 0 0 1 1 1 1 Transcription Regulator PIG-P PF08510.7 KFM10013.1 - 1e-38 131.8 1.3 1.2e-38 131.5 0.9 1.1 1 0 0 1 1 1 1 PIG-P DUF1469 PF07332.6 KFM10013.1 - 0.24 11.1 0.9 0.32 10.7 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) TPR_11 PF13414.1 KFM10014.1 - 1.1e-17 63.4 6.3 2.1e-12 46.4 0.1 4.7 2 2 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 KFM10014.1 - 3.5e-13 48.5 4.7 0.0017 17.9 0.0 5.1 4 0 0 4 4 4 4 Tetratricopeptide repeat zf-RING_2 PF13639.1 KFM10014.1 - 4.3e-12 45.6 12.6 4.3e-12 45.6 8.7 3.0 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 KFM10014.1 - 2.6e-08 33.8 6.9 2.6e-08 33.8 4.8 3.2 3 0 0 3 3 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KFM10014.1 - 2.8e-07 30.4 11.4 2.8e-07 30.4 7.9 3.5 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) TPR_2 PF07719.12 KFM10014.1 - 1.2e-06 27.9 10.5 0.16 11.9 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat zf-C3HC4 PF00097.20 KFM10014.1 - 1.6e-06 27.6 11.7 1.6e-06 27.6 8.1 2.8 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) TPR_12 PF13424.1 KFM10014.1 - 3e-06 27.0 3.4 0.082 12.8 0.0 4.0 2 1 1 3 3 3 3 Tetratricopeptide repeat Apc3 PF12895.2 KFM10014.1 - 5.7e-05 23.1 4.6 0.0016 18.5 0.5 2.9 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 KFM10014.1 - 0.00073 19.1 1.6 1.2 9.1 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat zf-Apc11 PF12861.2 KFM10014.1 - 0.00075 19.2 3.3 0.00075 19.2 2.3 2.7 2 1 1 3 3 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_17 PF13431.1 KFM10014.1 - 0.00088 19.2 2.7 0.055 13.6 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFM10014.1 - 0.066 13.5 3.1 8.1 6.8 0.0 3.7 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFM10014.1 - 0.14 12.8 0.5 1.9 9.2 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFM10014.1 - 0.36 11.5 1.2 1.3e+02 3.5 0.0 4.4 5 0 0 5 5 3 0 Tetratricopeptide repeat Vps26 PF03643.10 KFM10015.1 - 9e-68 228.0 0.2 1e-67 227.8 0.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 KFM10015.1 - 3.7e-07 30.0 0.1 1e-05 25.3 0.0 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LSM PF01423.17 KFM10015.1 - 0.24 10.9 0.9 27 4.4 0.0 3.0 3 0 0 3 3 3 0 LSM domain Pkinase PF00069.20 KFM10016.1 - 1.7e-53 181.4 0.0 2.8e-53 180.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM10016.1 - 3e-22 78.9 0.0 5.5e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase IRK PF01007.15 KFM10017.1 - 6.1e-164 544.7 0.8 7.6e-164 544.3 0.6 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 KFM10017.1 - 0.01 15.4 9.5 0.038 13.7 6.6 2.0 1 1 0 1 1 1 0 Ion channel IRK PF01007.15 KFM10018.1 - 5.4e-144 479.1 0.4 6.4e-144 478.8 0.3 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 KFM10018.1 - 0.0015 18.2 2.8 0.0033 17.0 1.9 1.7 1 1 0 1 1 1 1 Ion channel Ets PF00178.17 KFM10019.1 - 4.5e-40 135.6 0.8 8.2e-40 134.8 0.5 1.4 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.11 KFM10019.1 - 2e-26 91.5 0.0 3.6e-26 90.7 0.0 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_2 PF07647.12 KFM10019.1 - 0.0047 16.7 0.2 0.055 13.3 0.0 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFM10019.1 - 0.12 12.5 0.5 0.34 11.0 0.4 1.7 1 1 0 1 1 1 0 SAM domain (Sterile alpha motif) Ets PF00178.17 KFM10020.1 - 2.8e-40 136.3 2.5 5.5e-40 135.3 0.4 2.3 2 0 0 2 2 2 1 Ets-domain SAM_PNT PF02198.11 KFM10020.1 - 2e-34 117.1 1.3 4.1e-34 116.2 0.9 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain WD40 PF00400.27 KFM10022.1 - 2.1e-53 176.3 17.9 3.3e-09 36.2 0.1 9.2 10 0 0 10 10 10 8 WD domain, G-beta repeat Bromodomain PF00439.20 KFM10022.1 - 7.1e-36 122.0 0.1 2.9e-17 62.3 0.1 2.6 2 0 0 2 2 2 2 Bromodomain eIF2A PF08662.6 KFM10022.1 - 0.03 14.0 0.1 1.7 8.3 0.0 2.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A HMG14_17 PF01101.13 KFM10023.1 - 2.1e-07 31.5 12.3 2.2e-07 31.4 8.6 1.0 1 0 0 1 1 1 1 HMG14 and HMG17 F-112 PF09645.5 KFM10023.1 - 0.26 11.1 2.5 0.26 11.2 1.7 1.1 1 0 0 1 1 1 0 F-112 protein CHD5 PF04420.9 KFM10024.1 - 3.9e-45 153.4 1.2 4.3e-45 153.2 0.8 1.0 1 0 0 1 1 1 1 CHD5-like protein Lipoprotein_20 PF13942.1 KFM10024.1 - 0.068 12.6 2.3 0.094 12.2 1.6 1.2 1 0 0 1 1 1 0 YfhG lipoprotein DUF1640 PF07798.6 KFM10024.1 - 1.1 9.3 8.4 3.8 7.5 5.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) SH3BGR PF04908.10 KFM10025.1 - 1.5e-40 137.1 0.3 1.7e-40 136.9 0.2 1.0 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.19 KFM10025.1 - 0.0007 19.5 0.0 0.00097 19.0 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin I-set PF07679.11 KFM10027.1 - 1.1e-14 54.0 0.2 2.9e-06 27.0 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain C2-set_2 PF08205.7 KFM10027.1 - 3.8e-10 39.5 1.5 1.2e-06 28.3 0.0 2.3 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.1 KFM10027.1 - 1.8e-09 37.5 1.1 0.0009 19.3 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 KFM10027.1 - 9.7e-07 29.2 5.6 0.0012 19.2 0.0 3.1 2 1 0 2 2 2 2 Immunoglobulin domain C1-set PF07654.10 KFM10027.1 - 1e-06 28.6 1.3 7.5e-06 25.8 0.0 2.7 2 1 1 3 3 3 1 Immunoglobulin C1-set domain V-set PF07686.12 KFM10027.1 - 5.6e-06 26.2 1.0 0.0042 16.9 0.1 2.4 1 1 1 2 2 2 2 Immunoglobulin V-set domain Marek_A PF02124.10 KFM10027.1 - 2.2e-05 24.0 1.5 3.3e-05 23.4 1.0 1.3 1 0 0 1 1 1 1 Marek's disease glycoprotein A TMEM154 PF15102.1 KFM10027.1 - 0.00097 18.8 1.1 0.0018 17.9 0.8 1.4 1 0 0 1 1 1 1 TMEM154 protein family TMEM52 PF14979.1 KFM10027.1 - 0.0016 18.3 0.3 0.003 17.4 0.2 1.5 1 0 0 1 1 1 1 Transmembrane 52 Protocadherin PF08374.6 KFM10027.1 - 0.0033 17.0 0.9 0.0055 16.3 0.6 1.3 1 0 0 1 1 1 1 Protocadherin ig PF00047.20 KFM10027.1 - 0.0045 17.0 3.0 0.13 12.4 0.0 3.0 2 1 0 2 2 2 1 Immunoglobulin domain Orthoreo_P10 PF07204.6 KFM10027.1 - 0.015 15.0 0.2 0.036 13.8 0.1 1.7 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Glycophorin_A PF01102.13 KFM10027.1 - 0.018 14.7 0.1 0.039 13.7 0.1 1.5 1 0 0 1 1 1 0 Glycophorin A LRR19-TM PF15176.1 KFM10027.1 - 0.03 13.9 1.1 0.094 12.4 0.8 1.8 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain GP41 PF00517.12 KFM10027.1 - 0.032 13.8 0.5 0.052 13.1 0.4 1.4 1 0 0 1 1 1 0 Retroviral envelope protein PIRT PF15099.1 KFM10027.1 - 0.032 13.4 5.0 0.39 9.9 1.2 2.4 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family DUF1191 PF06697.7 KFM10027.1 - 0.047 12.4 0.0 0.066 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) C2-set PF05790.10 KFM10027.1 - 0.048 13.6 0.9 2.3 8.2 0.0 2.7 3 0 0 3 3 2 0 Immunoglobulin C2-set domain Shisa PF13908.1 KFM10027.1 - 0.053 13.6 1.8 0.096 12.8 1.3 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator HPIH PF13323.1 KFM10027.1 - 0.062 12.9 0.5 0.11 12.2 0.4 1.4 1 1 0 1 1 1 0 N-terminal domain with HPIH motif UPF0139 PF03669.8 KFM10027.1 - 0.075 12.5 0.1 0.17 11.4 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0139) DUF4389 PF14333.1 KFM10027.1 - 0.39 10.4 2.3 0.6 9.8 1.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) LSR PF05624.9 KFM10027.1 - 1.4 8.7 7.4 4.2 7.1 5.1 1.8 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) IQ PF00612.22 KFM10028.1 - 0.013 15.0 0.6 0.018 14.6 0.4 1.2 1 0 0 1 1 1 0 IQ calmodulin-binding motif Ca_chan_IQ PF08763.6 KFM10028.1 - 0.087 12.0 0.2 0.087 12.0 0.2 1.5 2 0 0 2 2 2 0 Voltage gated calcium channel IQ domain Ig_2 PF13895.1 KFM10029.1 - 1.8e-06 27.9 0.1 0.00027 20.9 0.0 2.4 1 1 1 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 KFM10029.1 - 0.00011 22.6 0.4 0.00045 20.6 0.1 2.0 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.20 KFM10029.1 - 0.091 12.9 0.2 0.79 9.8 0.0 2.4 2 1 0 2 2 2 0 Immunoglobulin domain Asp PF00026.18 KFM10030.1 - 9.5e-39 133.4 0.2 2.8e-38 131.9 0.2 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 KFM10030.1 - 1.8e-13 50.3 0.0 2.7e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Dynamin_M PF01031.15 KFM10032.1 - 1.5e-86 289.8 10.1 2.4e-86 289.1 7.0 1.2 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 KFM10032.1 - 2.8e-45 154.1 0.0 7.1e-45 152.8 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KFM10032.1 - 3.4e-16 58.8 1.6 2.2e-15 56.3 0.1 2.9 3 1 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KFM10032.1 - 0.00032 20.6 0.0 0.0013 18.7 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KFM10032.1 - 0.0094 16.4 0.0 0.033 14.6 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 KFM10032.1 - 0.014 15.3 2.9 0.09 12.7 0.0 3.2 3 1 0 3 3 3 0 AAA ATPase domain AAA_21 PF13304.1 KFM10032.1 - 0.017 15.1 0.2 0.052 13.5 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KFM10032.1 - 0.02 14.4 0.2 0.041 13.4 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Tht1 PF04163.7 KFM10032.1 - 0.024 13.0 6.0 0.15 10.4 0.4 2.2 2 0 0 2 2 2 0 Tht1-like nuclear fusion protein FliH PF02108.11 KFM10032.1 - 0.032 14.1 2.0 0.51 10.2 0.4 2.6 2 0 0 2 2 2 0 Flagellar assembly protein FliH ApoLp-III PF07464.6 KFM10032.1 - 0.053 13.5 2.0 1.7 8.6 0.0 3.4 4 0 0 4 4 3 0 Apolipophorin-III precursor (apoLp-III) FeoB_N PF02421.13 KFM10032.1 - 0.055 12.7 0.5 2.1 7.5 0.0 3.2 3 0 0 3 3 3 0 Ferrous iron transport protein B ABC_tran PF00005.22 KFM10032.1 - 0.13 12.5 1.4 0.28 11.5 0.0 2.3 3 0 0 3 3 2 0 ABC transporter FANCI_S1-cap PF14674.1 KFM10032.1 - 3.7 7.6 6.7 0.77 9.8 0.9 2.4 2 0 0 2 2 2 0 FANCI solenoid 1 cap P4Ha_N PF08336.6 KFM10032.1 - 4 7.2 8.6 0.34 10.7 0.1 3.1 3 1 1 4 4 4 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region AAA_23 PF13476.1 KFM10032.1 - 9.9 6.4 12.1 7.1 6.9 0.0 3.7 2 1 0 2 2 1 0 AAA domain Trypsin PF00089.21 KFM10033.1 - 3.2e-70 236.1 1.7 4.4e-70 235.7 1.2 1.2 1 0 0 1 1 1 1 Trypsin SRCR_2 PF15494.1 KFM10033.1 - 6e-30 103.3 0.1 1.2e-29 102.3 0.1 1.6 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain DUF1986 PF09342.6 KFM10033.1 - 3.3e-09 36.4 0.1 7e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Ldl_recept_a PF00057.13 KFM10033.1 - 7.1e-05 22.6 6.9 0.00022 21.0 4.8 1.9 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A SRCR PF00530.13 KFM10033.1 - 0.00016 21.9 2.0 0.00017 21.8 0.1 2.0 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain Trypsin_2 PF13365.1 KFM10033.1 - 0.00091 19.2 0.0 0.003 17.5 0.0 1.9 1 0 0 1 1 1 1 Trypsin-like peptidase domain Hepsin-SRCR PF09272.5 KFM10033.1 - 0.016 15.4 0.1 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 Hepsin, SRCR P12 PF12669.2 KFM10033.1 - 0.042 14.0 1.5 0.13 12.4 1.0 1.9 1 0 0 1 1 1 0 Virus attachment protein p12 family DUF3149 PF11346.3 KFM10033.1 - 0.18 11.3 1.4 0.34 10.5 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) zf-C2H2 PF00096.21 KFM10034.1 - 1.8e-51 169.4 140.7 6.9e-06 26.1 0.9 18.1 18 0 0 18 18 18 17 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM10034.1 - 1.5e-43 143.9 106.3 0.00018 21.6 0.3 17.5 17 0 0 17 17 17 15 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFM10034.1 - 5.7e-36 121.0 113.3 3.5e-05 23.8 0.3 18.1 18 0 0 18 18 18 11 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFM10034.1 - 2e-18 65.9 98.4 0.0029 17.7 0.1 17.3 18 0 0 18 18 18 11 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM10034.1 - 8.9e-16 57.4 103.8 0.0082 16.3 0.2 17.2 17 0 0 17 17 17 10 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFM10034.1 - 4.9e-05 23.0 104.5 0.014 15.2 1.0 17.0 17 1 1 18 18 18 8 C2H2-type zinc finger SET PF00856.23 KFM10034.1 - 0.0032 17.7 1.2 0.017 15.4 0.0 2.8 3 0 0 3 3 3 1 SET domain zf-C2HC_2 PF13913.1 KFM10034.1 - 0.0066 16.0 51.2 0.051 13.2 0.1 11.0 11 0 0 11 11 11 4 zinc-finger of a C2HC-type C2 PF00168.25 KFM10035.1 - 4.4e-08 32.8 0.0 1.9e-07 30.8 0.0 2.1 1 0 0 1 1 1 1 C2 domain CEP76-C2 PF15627.1 KFM10035.1 - 0.038 13.5 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 CEP76 C2 domain BTB PF00651.26 KFM10036.1 - 2.9e-26 91.6 0.1 5.6e-26 90.7 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.21 KFM10036.1 - 1.5e-14 53.3 77.7 0.00088 19.4 1.2 9.3 9 0 0 9 9 9 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM10036.1 - 9.9e-12 44.3 73.6 0.0047 17.1 0.1 9.5 8 1 0 8 8 8 5 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFM10036.1 - 0.00011 22.3 68.4 0.0026 17.9 3.2 10.8 10 1 0 10 10 10 5 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFM10036.1 - 0.00039 20.4 49.8 0.3 11.2 1.7 8.9 9 0 0 9 9 9 5 Zinc-finger double-stranded RNA-binding Desulfoferrod_N PF06397.7 KFM10036.1 - 1.6 8.2 7.8 38 3.7 0.1 4.5 4 0 0 4 4 4 0 Desulfoferrodoxin, N-terminal domain zf-CHCC PF10276.4 KFM10036.1 - 1.7 8.5 11.5 0.82 9.5 0.5 3.5 3 0 0 3 3 3 0 Zinc-finger domain zf-met PF12874.2 KFM10036.1 - 2.2 8.6 40.6 0.09 13.0 1.6 7.4 7 0 0 7 7 7 0 Zinc-finger of C2H2 type Trefoil PF00088.13 KFM10037.1 - 1.4e-32 111.0 19.9 3.1e-16 58.7 4.2 2.1 2 0 0 2 2 2 2 Trefoil (P-type) domain Trypsin PF00089.21 KFM10038.1 - 8.9e-73 244.5 0.7 1.3e-72 243.9 0.5 1.2 1 0 0 1 1 1 1 Trypsin SRCR_2 PF15494.1 KFM10038.1 - 1.6e-26 92.4 1.8 2.7e-26 91.6 1.2 1.4 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR PF00530.13 KFM10038.1 - 3.2e-09 36.9 0.4 1.1e-08 35.2 0.3 1.9 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain DUF1986 PF09342.6 KFM10038.1 - 8e-07 28.6 0.1 1.5e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Ldl_recept_a PF00057.13 KFM10038.1 - 2.9e-06 27.0 7.0 7e-06 25.8 4.9 1.7 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Hepsin-SRCR PF09272.5 KFM10038.1 - 0.00058 20.0 0.6 0.0013 18.9 0.4 1.6 1 0 0 1 1 1 1 Hepsin, SRCR Trypsin_2 PF13365.1 KFM10038.1 - 0.0023 17.9 0.0 0.0058 16.6 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain His_Phos_1 PF00300.17 KFM10039.1 - 2.6e-23 82.8 0.0 1.5e-22 80.3 0.0 2.2 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) SH3_9 PF14604.1 KFM10039.1 - 5.4e-14 51.4 0.0 1e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFM10039.1 - 7.4e-05 22.1 0.0 0.00015 21.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM10039.1 - 8.6e-05 21.8 0.0 0.00018 20.8 0.0 1.6 1 0 0 1 1 1 1 SH3 domain UBA PF00627.26 KFM10039.1 - 0.00069 19.3 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain 2_5_RNA_ligase2 PF13563.1 KFM10039.1 - 0.011 15.4 0.2 0.036 13.7 0.1 1.8 1 1 0 1 1 1 0 2'-5' RNA ligase superfamily His_Phos_2 PF00328.17 KFM10039.1 - 0.098 11.9 0.4 0.59 9.4 0.3 2.2 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) LigT_PEase PF02834.11 KFM10039.1 - 0.12 12.3 0.2 14 5.7 0.0 2.7 2 0 0 2 2 2 0 LigT like Phosphoesterase MORN PF02493.15 KFM10040.1 - 1.6e-34 115.5 47.5 1.7e-09 36.8 1.8 7.5 7 0 0 7 7 7 7 MORN repeat MFS_1 PF07690.11 KFM10041.1 - 1.1e-34 119.6 36.0 8e-30 103.7 17.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2985 PF11204.3 KFM10041.1 - 0.038 13.7 2.4 1.4 8.7 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2985) PDEase_I PF00233.14 KFM10042.1 - 8e-67 225.4 1.8 8e-67 225.4 1.3 1.6 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Histone_HNS PF00816.16 KFM10042.1 - 0.88 10.1 4.4 1 9.9 0.1 2.9 3 0 0 3 3 3 0 H-NS histone family WD40 PF00400.27 KFM10043.1 - 3.8e-12 45.5 0.0 8.4e-05 22.3 0.0 4.1 3 1 0 3 3 3 3 WD domain, G-beta repeat AF-4 PF05110.8 KFM10044.1 - 1.4 6.7 36.4 2.4 5.9 25.0 1.4 1 1 0 1 1 1 0 AF-4 proto-oncoprotein Homeobox_KN PF05920.6 KFM10045.1 - 2.3e-19 68.7 0.8 4.4e-19 67.9 0.5 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KFM10045.1 - 2.9e-08 33.1 0.2 5.8e-08 32.2 0.2 1.5 1 0 0 1 1 1 1 Homeobox domain CBS PF00571.23 KFM10046.1 - 4.7e-08 32.6 0.0 4.1e-06 26.4 0.0 2.3 2 1 0 2 2 2 2 CBS domain Poxvirus_B22R_C PF13168.1 KFM10046.1 - 0.00023 20.5 0.0 0.00028 20.2 0.0 1.1 1 0 0 1 1 1 1 Poxvirus B22R protein C-terminal PALP PF00291.20 KFM10047.1 - 3.3e-17 62.6 0.0 3.5e-17 62.5 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Integrase_Zn PF02022.14 KFM10047.1 - 0.0058 16.0 0.4 0.58 9.6 0.1 2.2 2 0 0 2 2 2 2 Integrase Zinc binding domain Methyltransf_12 PF08242.7 KFM10047.1 - 0.056 13.9 0.0 0.076 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KFM10047.1 - 0.09 13.3 0.0 0.11 13.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain FIST PF08495.5 KFM10047.1 - 0.093 11.8 0.2 0.22 10.6 0.2 1.6 1 1 0 1 1 1 0 FIST N domain Glyco_tran_WecB PF03808.8 KFM10047.1 - 0.11 11.9 0.0 0.12 11.7 0.0 1.3 1 1 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family PALP PF00291.20 KFM10049.1 - 6.4e-62 209.5 0.0 8.1e-62 209.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 KFM10049.1 - 1.6e-09 37.3 0.1 4.1e-08 32.8 0.0 2.6 2 0 0 2 2 2 1 CBS domain zf-CCCH PF00642.19 KFM10050.1 - 1.3e-13 50.2 16.8 5.9e-07 29.0 2.2 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 KFM10050.1 - 1e-08 34.9 0.0 2.5e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFM10050.1 - 3.7e-07 29.6 0.0 6e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM10050.1 - 0.00034 20.5 0.1 0.00071 19.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CART PF06373.6 KFM10050.1 - 0.017 15.0 1.4 0.34 10.9 0.3 2.9 3 0 0 3 3 3 0 Cocaine and amphetamine regulated transcript protein (CART) KMP11 PF03037.11 KFM10050.1 - 0.017 15.7 0.4 0.73 10.4 0.2 2.2 2 0 0 2 2 2 0 Kinetoplastid membrane protein 11 Nup35_RRM_2 PF14605.1 KFM10050.1 - 0.03 14.0 0.2 0.061 13.1 0.1 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Benyvirus_14KDa PF07255.6 KFM10050.1 - 0.074 12.9 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Benyvirus 14KDa protein HSP20 PF00011.16 KFM10051.1 - 5.2e-30 103.3 0.0 6.3e-30 103.0 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Crystallin PF00525.13 KFM10051.1 - 2.4e-26 91.6 1.1 4.7e-26 90.7 0.8 1.5 1 0 0 1 1 1 1 Alpha crystallin A chain, N terminal SprB PF13573.1 KFM10051.1 - 0.18 11.3 0.4 0.28 10.8 0.3 1.2 1 0 0 1 1 1 0 SprB repeat Pkinase PF00069.20 KFM10052.1 - 3.5e-78 262.3 0.1 1.2e-77 260.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM10052.1 - 2.4e-39 135.0 0.0 4.2e-39 134.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM10052.1 - 6.4e-08 31.9 0.0 1e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like CCDC144C PF14915.1 KFM10053.1 - 0.00031 19.7 3.4 0.00061 18.8 2.4 1.4 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region HEAT PF02985.17 KFM10053.1 - 0.0036 17.2 0.3 0.016 15.2 0.2 2.2 1 0 0 1 1 1 1 HEAT repeat VHS PF00790.14 KFM10053.1 - 0.0058 16.2 0.1 0.43 10.2 0.0 2.6 2 0 0 2 2 2 1 VHS domain RasGEF_N_2 PF14663.1 KFM10053.1 - 0.0066 16.3 0.0 0.026 14.4 0.0 2.0 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Spc7 PF08317.6 KFM10053.1 - 0.0084 14.8 6.5 0.015 14.0 4.5 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF972 PF06156.8 KFM10053.1 - 0.015 15.6 4.2 0.015 15.6 2.9 2.1 2 1 0 2 2 1 0 Protein of unknown function (DUF972) DUF1409 PF07197.7 KFM10053.1 - 0.015 15.3 4.5 0.015 15.3 3.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) DUF3584 PF12128.3 KFM10053.1 - 0.016 12.5 4.6 0.024 12.0 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) APG6 PF04111.7 KFM10053.1 - 0.054 12.5 5.1 0.1 11.6 3.5 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF383 PF04063.9 KFM10053.1 - 0.075 12.5 1.4 0.14 11.6 0.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF383) Atg14 PF10186.4 KFM10053.1 - 0.13 11.2 8.5 1.5 7.7 4.6 2.3 1 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Mnd1 PF03962.10 KFM10053.1 - 0.18 11.4 6.2 0.27 10.8 3.9 1.6 2 0 0 2 2 2 0 Mnd1 family DUF4201 PF13870.1 KFM10053.1 - 0.68 9.3 12.4 0.28 10.6 6.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) THOC7 PF05615.8 KFM10053.1 - 1.8 8.8 11.3 0.74 10.0 5.7 1.9 2 0 0 2 2 2 0 Tho complex subunit 7 DUF4259 PF14078.1 KFM10053.1 - 2 8.9 5.0 5.8 7.4 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4259) TPR_MLP1_2 PF07926.7 KFM10053.1 - 4.3 7.0 14.1 0.036 13.8 3.7 2.0 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Nop52 PF05997.7 KFM10054.1 - 3.4e-66 222.8 3.6 3.4e-66 222.8 2.5 2.1 2 1 0 2 2 2 1 Nucleolar protein,Nop52 PfkB PF00294.19 KFM10055.1 - 4.8e-29 101.4 0.0 5.9e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 KFM10055.1 - 1.8e-19 69.9 0.0 2.8e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase HpcH_HpaI PF03328.9 KFM10055.1 - 0.0026 16.7 0.0 0.006 15.4 0.0 1.6 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Acyltransferase PF01553.16 KFM10056.1 - 1.2e-13 50.6 0.0 2.1e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase TRAPPC10 PF12584.3 KFM10058.1 - 0.00031 20.2 0.0 0.00069 19.1 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 TRAPPC10 PF12584.3 KFM10059.1 - 1.2e-22 79.9 0.0 1.7e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 WD40 PF00400.27 KFM10060.1 - 2.5e-41 138.1 32.2 1.5e-12 46.8 0.1 10.6 12 0 0 12 12 12 6 WD domain, G-beta repeat Utp12 PF04003.7 KFM10060.1 - 1.4e-29 102.1 0.9 2.2e-29 101.5 0.6 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 KFM10060.1 - 1.7e-08 34.4 0.9 0.033 13.9 0.0 5.0 2 1 2 5 5 5 4 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 KFM10060.1 - 0.0015 18.1 0.2 1.1 9.0 0.0 3.8 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Utp13 PF08625.6 KFM10060.1 - 0.011 15.3 0.5 0.043 13.4 0.3 2.0 1 1 0 1 1 1 0 Utp13 specific WD40 associated domain DJ-1_PfpI PF01965.19 KFM10061.1 - 6.3e-14 51.6 0.4 8.4e-14 51.2 0.3 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family V-set PF07686.12 KFM10062.1 - 2.1e-11 43.6 2.1 6.8e-09 35.6 0.0 2.7 2 1 0 2 2 2 2 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM10062.1 - 1.5e-09 37.6 0.1 6.9e-09 35.5 0.1 2.1 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain I-set PF07679.11 KFM10062.1 - 4.5e-09 36.0 0.0 0.0043 16.8 0.0 2.7 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.1 KFM10062.1 - 6.1e-09 36.2 7.8 1.5e-05 25.3 1.6 4.5 3 2 1 4 4 4 2 Immunoglobulin domain Ig_2 PF13895.1 KFM10062.1 - 1.2e-08 34.9 3.1 0.0031 17.6 0.4 3.0 3 1 0 3 3 3 2 Immunoglobulin domain ig PF00047.20 KFM10062.1 - 3.6e-07 30.1 2.0 0.0095 16.0 0.1 3.7 3 2 1 4 4 3 2 Immunoglobulin domain C1-set PF07654.10 KFM10062.1 - 1.1e-06 28.5 3.1 4.8e-05 23.2 0.0 3.3 2 1 0 2 2 2 1 Immunoglobulin C1-set domain MLANA PF14991.1 KFM10062.1 - 0.00038 20.4 2.0 0.00097 19.1 1.2 1.9 1 1 0 1 1 1 1 Protein melan-A Lep_receptor_Ig PF06328.6 KFM10062.1 - 0.00065 19.5 1.0 0.054 13.3 0.0 3.1 3 1 0 3 3 3 1 Ig-like C2-type domain DUF4328 PF14219.1 KFM10062.1 - 0.0033 16.7 0.0 0.0056 16.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4328) TMEM223 PF14640.1 KFM10062.1 - 0.063 13.2 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 223 DUF2987 PF11205.3 KFM10062.1 - 0.064 12.9 0.1 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2987) SKG6 PF08693.5 KFM10062.1 - 0.29 10.4 2.7 0.64 9.3 1.9 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PIP49_C PF12260.3 KFM10063.1 - 4e-42 143.7 0.0 7.5e-42 142.8 0.0 1.4 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 DUF3342 PF11822.3 KFM10063.1 - 0.026 13.6 0.0 0.048 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) Perm-CXXC PF15629.1 KFM10063.1 - 0.095 12.7 0.4 0.41 10.6 0.2 2.2 1 0 0 1 1 1 0 Permuted single zf-CXXC unit JmjC PF02373.17 KFM10064.1 - 3.5e-33 114.2 1.9 3.5e-33 114.2 1.3 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase TPR_1 PF00515.23 KFM10064.1 - 1.1e-30 103.9 15.3 1.6e-06 27.4 0.1 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.1 KFM10064.1 - 3.7e-24 84.1 16.4 3.5e-08 32.9 0.1 5.6 6 0 0 6 6 6 4 TPR repeat TPR_2 PF07719.12 KFM10064.1 - 1.6e-19 68.1 14.2 0.001 18.7 0.3 8.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.1 KFM10064.1 - 5.3e-15 54.2 4.2 7e-05 22.7 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFM10064.1 - 2.3e-14 53.0 13.1 0.00051 19.9 0.1 5.9 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.1 KFM10064.1 - 1.3e-11 43.3 14.0 0.13 12.1 0.5 8.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFM10064.1 - 3.6e-11 43.4 3.0 0.023 15.3 0.0 5.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFM10064.1 - 4.3e-07 29.2 6.8 0.77 9.6 0.1 7.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFM10064.1 - 1e-06 28.7 3.2 0.56 10.9 0.0 5.4 3 1 3 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 KFM10064.1 - 5.8e-05 22.8 3.0 0.016 15.0 0.1 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFM10064.1 - 0.00012 22.3 5.6 0.069 13.4 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat SNAP PF14938.1 KFM10064.1 - 0.00045 19.4 12.2 0.034 13.2 1.2 3.2 2 1 0 3 3 3 2 Soluble NSF attachment protein, SNAP Apc3 PF12895.2 KFM10064.1 - 0.12 12.5 18.3 1.3 9.2 0.1 4.7 1 1 6 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KFM10064.1 - 2.1 9.0 10.6 20 5.9 0.1 6.6 8 0 0 8 8 8 0 Tetratricopeptide repeat FUN14 PF04930.10 KFM10065.1 - 1.8e-35 121.2 3.0 2.1e-35 120.9 2.1 1.1 1 0 0 1 1 1 1 FUN14 family DUF1126 PF06565.7 KFM10066.1 - 2e-40 135.9 4.3 3.2e-15 55.3 0.1 3.5 3 0 0 3 3 3 3 Repeat of unknown function (DUF1126) Cys_knot PF00007.17 KFM10067.1 - 2e-06 27.8 13.0 2.9e-06 27.3 9.0 1.3 1 0 0 1 1 1 1 Cystine-knot domain DAN PF03045.10 KFM10067.1 - 2.7e-05 23.5 8.2 3.1e-05 23.3 5.7 1.1 1 0 0 1 1 1 1 DAN domain Amino_oxidase PF01593.19 KFM10068.1 - 6.1e-70 236.5 0.0 7.5e-70 236.2 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KFM10068.1 - 3.1e-08 33.5 0.0 8.9e-08 32.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFM10068.1 - 8.5e-05 21.6 0.0 0.12 11.2 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KFM10068.1 - 0.1 12.6 0.0 4 7.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase KH_5 PF13184.1 KFM10068.1 - 0.16 11.8 0.3 10 5.9 0.1 2.5 2 0 0 2 2 2 0 NusA-like KH domain Amino_oxidase PF01593.19 KFM10069.1 - 1e-65 222.5 0.0 1.3e-65 222.3 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KFM10069.1 - 8.6e-10 38.5 0.0 2.7e-09 36.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFM10069.1 - 0.0059 15.5 0.1 0.36 9.6 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase 7tm_1 PF00001.16 KFM10071.1 - 1.9e-20 73.0 22.5 6.4e-11 41.8 2.1 2.1 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) DUF2659 PF10858.3 KFM10071.1 - 0.032 13.6 0.3 0.073 12.4 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2659) Afaf PF15339.1 KFM10071.1 - 0.1 12.1 1.5 0.27 10.8 0.1 2.1 2 1 0 2 2 2 0 Acrosome formation-associated factor DUF3754 PF12576.3 KFM10071.1 - 5.6 6.5 6.3 0.41 10.2 0.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3754) DUF1211 PF06736.6 KFM10071.1 - 8.8 6.5 8.4 3.6 7.7 2.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1211) Guanylate_kin PF00625.16 KFM10072.1 - 4.6e-61 205.4 0.1 6.3e-61 205.0 0.1 1.2 1 0 0 1 1 1 1 Guanylate kinase SH3_2 PF07653.12 KFM10072.1 - 6.1e-13 48.0 0.0 1.1e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM10072.1 - 1.2e-08 34.2 0.9 3.1e-08 32.8 0.7 1.8 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFM10072.1 - 1e-06 28.2 0.0 2.2e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Ribosomal_L2_C PF03947.13 KFM10073.1 - 1.5e-41 141.2 1.5 2e-41 140.8 1.1 1.1 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KFM10073.1 - 1.5e-07 31.2 0.0 4.5e-07 29.7 0.0 1.9 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain UCH PF00443.24 KFM10074.1 - 2.8e-60 203.7 0.6 7.7e-60 202.2 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFM10074.1 - 1.1e-24 87.4 0.0 3.3e-19 69.4 0.0 2.8 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Med14 PF08638.6 KFM10075.1 - 2.5e-60 203.0 0.1 7.6e-60 201.5 0.0 1.9 2 0 0 2 2 2 1 Mediator complex subunit MED14 RE_SinI PF09570.5 KFM10075.1 - 0.03 13.3 0.0 0.068 12.1 0.0 1.5 1 0 0 1 1 1 0 SinI restriction endonuclease Armet PF10208.4 KFM10075.1 - 0.2 11.2 0.1 0.39 10.3 0.1 1.4 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding Renin_r PF07850.9 KFM10076.1 - 2.6e-45 152.7 2.5 4.1e-45 152.1 1.7 1.3 1 0 0 1 1 1 1 Renin receptor-like protein Glycophorin_A PF01102.13 KFM10076.1 - 0.064 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A Ank_2 PF12796.2 KFM10077.1 - 8.1e-19 67.7 0.4 1.7e-18 66.7 0.3 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFM10077.1 - 4.5e-17 60.9 1.2 1.1e-05 24.9 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 KFM10077.1 - 2.1e-14 52.1 0.8 0.0015 18.5 0.1 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 KFM10077.1 - 1e-13 51.0 2.0 2.9e-08 33.7 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFM10077.1 - 1.3e-13 51.0 4.0 5.9e-08 33.0 0.2 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Tetraspannin PF00335.15 KFM10079.1 - 6.2e-44 149.8 8.0 7.3e-44 149.6 5.5 1.1 1 0 0 1 1 1 1 Tetraspanin family OTCace PF00185.19 KFM10080.1 - 1.6e-47 161.3 0.0 2.3e-47 160.8 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.16 KFM10080.1 - 2.4e-42 143.9 0.0 4.3e-42 143.1 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain DUF2666 PF10869.3 KFM10080.1 - 0.12 12.4 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2666) RCC1 PF00415.13 KFM10081.1 - 3.4e-70 232.0 16.9 3.3e-12 46.4 0.1 8.2 7 1 1 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KFM10081.1 - 1.6e-39 132.7 21.9 7.4e-09 35.0 0.1 7.9 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat Kelch_2 PF07646.10 KFM10081.1 - 0.0055 16.4 0.2 6.2 6.7 0.0 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 KFM10081.1 - 0.007 16.1 7.7 2.1 8.1 0.0 4.7 6 0 0 6 6 6 2 Galactose oxidase, central domain IRS PF02174.12 KFM10081.1 - 0.11 12.1 0.4 11 5.6 0.0 2.6 2 0 0 2 2 2 0 PTB domain (IRS-1 type) DUF4174 PF13778.1 KFM10082.1 - 8.9e-28 96.7 0.0 1.2e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4174) HYR PF02494.11 KFM10082.1 - 1.5e-26 92.2 0.0 2.6e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 HYR domain Sushi PF00084.15 KFM10082.1 - 1.7e-25 89.1 24.8 1.5e-10 41.2 2.8 3.4 2 1 1 3 3 3 3 Sushi domain (SCR repeat) C2 PF00168.25 KFM10083.1 - 5.2e-42 141.5 0.5 2.9e-20 71.8 0.1 2.4 2 0 0 2 2 2 2 C2 domain FYVE_2 PF02318.11 KFM10083.1 - 1.9e-18 66.4 10.8 3.2e-18 65.7 7.5 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger Tctex-1 PF03645.8 KFM10084.1 - 1.2e-34 118.1 2.6 1.4e-34 118.0 1.8 1.0 1 0 0 1 1 1 1 Tctex-1 family NAD_binding_6 PF08030.7 KFM10085.1 - 1.8e-37 128.6 0.0 2.9e-37 127.9 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KFM10085.1 - 8.5e-21 73.8 0.0 1.7e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KFM10085.1 - 7.5e-20 71.2 6.6 7.5e-20 71.2 4.6 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KFM10085.1 - 1.9e-06 27.8 0.0 4.1e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KFM10085.1 - 0.0013 19.3 0.0 0.019 15.5 0.0 2.4 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain XK-related PF09815.4 KFM10086.1 - 6.5e-60 202.8 20.8 7.7e-60 202.6 14.4 1.1 1 0 0 1 1 1 1 XK-related protein Pox_polyA_pol PF03296.8 KFM10086.1 - 0.058 12.9 0.4 0.16 11.4 0.3 1.7 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase nucleotidyltransferase domain LANC_like PF05147.8 KFM10087.1 - 3.2e-59 200.2 0.0 4e-59 199.9 0.0 1.0 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein C5-epim_C PF06662.8 KFM10087.1 - 0.0047 16.2 1.1 0.73 9.0 0.1 2.3 1 1 1 2 2 2 2 D-glucuronyl C5-epimerase C-terminus DUF1680 PF07944.7 KFM10087.1 - 0.062 11.5 0.0 0.38 8.9 0.0 1.8 1 1 1 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) Motile_Sperm PF00635.21 KFM10088.1 - 8.5e-07 28.6 1.6 0.072 12.7 0.2 4.6 4 0 0 4 4 4 3 MSP (Major sperm protein) domain Gal-bind_lectin PF00337.17 KFM10089.1 - 0.0033 16.7 0.0 0.013 14.8 0.0 1.9 2 1 1 3 3 3 1 Galactoside-binding lectin CH PF00307.26 KFM10090.1 - 6.3e-08 32.6 0.0 1.3e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFM10090.1 - 2.9e-05 23.6 0.1 7.1e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 CAMSAP CH domain Claudin_2 PF13903.1 KFM10095.1 - 9.4e-12 44.9 10.6 1.1e-11 44.7 7.4 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HGMIC_fpl PF10242.4 KFM10095.1 - 0.015 15.3 3.8 0.021 14.8 2.6 1.2 1 0 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein Git3 PF11710.3 KFM10095.1 - 0.017 14.7 1.0 0.019 14.5 0.7 1.1 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 Claudin_3 PF06653.6 KFM10095.1 - 0.063 12.9 3.6 0.085 12.5 2.5 1.2 1 0 0 1 1 1 0 Tight junction protein, Claudin-like ApoO PF09769.4 KFM10095.1 - 0.14 11.8 1.4 0.2 11.3 1.0 1.3 1 0 0 1 1 1 0 Apolipoprotein O DUF3525 PF12039.3 KFM10095.1 - 0.17 10.3 0.3 0.2 10.1 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) Yip1 PF04893.12 KFM10095.1 - 0.9 9.0 12.7 1.4 8.4 8.8 1.3 1 1 0 1 1 1 0 Yip1 domain DUF131 PF01998.12 KFM10095.1 - 0.94 8.8 3.8 1.2 8.5 1.4 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF131 DUF4064 PF13273.1 KFM10095.1 - 1.8 8.6 6.2 24 5.0 2.8 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF485 PF04341.7 KFM10095.1 - 2 8.1 9.8 0.084 12.5 1.8 1.9 1 1 1 2 2 2 0 Protein of unknown function, DUF485 2TM PF13239.1 KFM10095.1 - 3.8 7.6 6.7 0.14 12.2 0.5 1.6 2 0 0 2 2 2 0 2TM domain Yae1_N PF09811.4 KFM10096.1 - 4.5e-13 48.4 33.8 0.0014 18.1 6.2 3.1 1 1 1 2 2 2 2 Essential protein Yae1, N terminal Spectrin PF00435.16 KFM10098.1 - 2e-157 513.3 262.8 2.9e-17 62.8 3.0 22.0 22 0 0 22 22 22 20 Spectrin repeat CH PF00307.26 KFM10098.1 - 8.2e-38 128.7 5.1 6e-19 68.0 0.0 6.0 4 0 0 4 4 4 3 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFM10098.1 - 5.7e-09 35.5 0.0 3.6e-05 23.3 0.0 3.7 3 0 0 3 3 3 2 CAMSAP CH domain DUF2051 PF09738.4 KFM10101.1 - 0.0028 16.9 0.7 0.0039 16.5 0.5 1.3 1 0 0 1 1 1 1 Double stranded RNA binding protein (DUF2051) Striatin PF08232.7 KFM10101.1 - 0.0036 17.6 1.5 0.0036 17.6 1.0 1.5 2 0 0 2 2 2 1 Striatin family Tropomyosin_1 PF12718.2 KFM10101.1 - 0.0096 15.7 0.8 0.0096 15.7 0.6 1.6 2 0 0 2 2 2 1 Tropomyosin like PspA_IM30 PF04012.7 KFM10101.1 - 0.023 14.0 2.8 0.041 13.2 1.9 1.4 1 0 0 1 1 1 0 PspA/IM30 family Syntaxin PF00804.20 KFM10101.1 - 0.028 14.5 2.2 0.038 14.1 0.5 1.8 2 0 0 2 2 2 0 Syntaxin Nop25 PF09805.4 KFM10101.1 - 0.03 14.3 0.2 0.04 13.9 0.1 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF892 PF05974.7 KFM10101.1 - 0.055 13.2 1.0 0.07 12.9 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF892) DUF4600 PF15372.1 KFM10101.1 - 0.078 13.2 1.4 0.11 12.6 1.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) DUF972 PF06156.8 KFM10101.1 - 0.17 12.2 3.9 0.075 13.3 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Flg_hook PF02120.11 KFM10101.1 - 0.18 11.4 6.2 0.44 10.2 3.4 2.3 2 1 0 2 2 1 0 Flagellar hook-length control protein FliK bZIP_1 PF00170.16 KFM10101.1 - 0.62 10.0 8.7 0.11 12.4 2.1 2.4 3 0 0 3 3 2 0 bZIP transcription factor HALZ PF02183.13 KFM10101.1 - 1.4 8.7 10.0 4.8 6.9 0.2 2.6 2 1 0 2 2 2 0 Homeobox associated leucine zipper CCDC-167 PF15188.1 KFM10101.1 - 1.6 8.7 4.4 17 5.4 0.1 2.4 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 DUF904 PF06005.7 KFM10101.1 - 3.4 8.0 10.6 7.1 7.0 3.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF904) CUE PF02845.11 KFM10102.1 - 1.2e-09 37.4 0.2 3.4e-09 36.0 0.1 1.8 2 0 0 2 2 2 1 CUE domain zf-RanBP PF00641.13 KFM10102.1 - 4.7e-05 22.4 1.7 4.7e-05 22.4 1.2 1.8 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others FGGY_N PF00370.16 KFM10103.1 - 6.3e-78 261.4 0.0 8.9e-78 260.9 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 KFM10103.1 - 3.9e-65 219.1 0.3 7e-65 218.3 0.1 1.5 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DUF4569 PF15133.1 KFM10105.1 - 2.4e-113 378.5 9.0 2.8e-113 378.3 6.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4569) TIR PF01582.15 KFM10107.1 - 1.7e-26 92.3 0.1 4.3e-26 91.0 0.0 1.7 2 0 0 2 2 2 1 TIR domain Ig_3 PF13927.1 KFM10107.1 - 4.6e-07 30.2 0.0 1.1e-06 29.0 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 KFM10107.1 - 3.7e-06 26.7 0.0 6.7e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 KFM10107.1 - 8e-05 22.6 0.0 0.00023 21.2 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain TIR_2 PF13676.1 KFM10107.1 - 9.2e-05 22.5 0.0 0.00022 21.3 0.0 1.6 1 0 0 1 1 1 1 TIR domain Ig_2 PF13895.1 KFM10107.1 - 0.00025 21.0 0.0 0.00064 19.7 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 KFM10109.1 - 0.00014 21.6 0.0 0.00015 21.5 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.12 KFM10109.1 - 0.00041 20.2 0.1 0.00044 20.1 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.1 KFM10109.1 - 0.013 16.0 0.0 0.019 15.4 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin domain Ig_2 PF13895.1 KFM10109.1 - 0.015 15.4 0.0 0.015 15.4 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain V-set_CD47 PF08204.6 KFM10109.1 - 0.045 13.5 0.0 0.045 13.5 0.0 1.1 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain Sp38 PF07354.7 KFM10109.1 - 0.058 12.0 0.0 0.058 12.0 0.0 1.1 1 0 0 1 1 1 0 Zona-pellucida-binding protein (Sp38) ig PF00047.20 KFM10109.1 - 0.13 12.4 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin domain Endostatin PF06482.6 KFM10113.1 - 2.8e-129 430.9 0.0 3.6e-129 430.6 0.0 1.1 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin Collagen PF01391.13 KFM10113.1 - 4.7e-63 208.5 356.4 1.5e-08 34.0 20.9 16.3 10 5 5 15 15 15 13 Collagen triple helix repeat (20 copies) Laminin_G_3 PF13385.1 KFM10113.1 - 6.4e-05 23.2 0.0 0.00013 22.2 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Folate_carrier PF01770.13 KFM10114.1 - 2.4e-166 553.3 15.2 2.8e-166 553.1 10.5 1.0 1 0 0 1 1 1 1 Reduced folate carrier MFS_1 PF07690.11 KFM10114.1 - 2.3e-09 36.4 30.3 2.7e-09 36.2 21.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily KH_1 PF00013.24 KFM10115.1 - 3.2e-41 138.7 13.8 1.6e-17 62.8 0.2 4.1 4 0 0 4 4 4 3 KH domain KH_3 PF13014.1 KFM10115.1 - 3.7e-29 99.8 21.8 1.3e-13 50.2 0.3 4.0 4 0 0 4 4 4 3 KH domain KH_2 PF07650.12 KFM10115.1 - 7.1e-11 41.5 1.8 1.7e-05 24.3 0.0 2.9 3 0 0 3 3 3 2 KH domain KH_4 PF13083.1 KFM10115.1 - 4.6e-05 22.9 0.6 2.2 8.0 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 KFM10115.1 - 0.0032 17.2 3.2 1.1 9.0 0.1 2.6 3 0 0 3 3 3 2 NusA-like KH domain VWA PF00092.23 KFM10116.1 - 2.5e-88 294.4 5.0 7.5e-31 107.2 0.0 3.1 3 0 0 3 3 3 3 von Willebrand factor type A domain Collagen PF01391.13 KFM10116.1 - 1.5e-51 171.7 205.3 3.6e-10 39.2 14.9 7.2 1 1 6 7 7 7 7 Collagen triple helix repeat (20 copies) VWA_2 PF13519.1 KFM10116.1 - 1.7e-37 129.1 0.4 9.5e-15 55.1 0.3 3.1 3 0 0 3 3 3 3 von Willebrand factor type A domain vWA-TerF-like PF10138.4 KFM10116.1 - 4.2e-08 33.2 1.7 2.6e-07 30.6 0.4 2.6 3 0 0 3 3 3 1 vWA found in TerF C terminus DUF1194 PF06707.6 KFM10116.1 - 1e-07 31.1 1.2 0.0002 20.4 0.6 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1194) Integrin_beta PF00362.13 KFM10116.1 - 0.079 11.8 0.0 0.19 10.5 0.0 1.5 2 0 0 2 2 2 0 Integrin, beta chain VWA PF00092.23 KFM10117.1 - 5.3e-82 273.8 7.1 2.2e-34 118.7 0.1 3.1 3 0 0 3 3 3 3 von Willebrand factor type A domain Collagen PF01391.13 KFM10117.1 - 1.4e-51 171.9 208.1 8.4e-10 38.0 17.4 7.3 1 1 5 6 6 6 5 Collagen triple helix repeat (20 copies) VWA_2 PF13519.1 KFM10117.1 - 4.2e-30 105.0 1.3 5.1e-09 36.4 0.0 3.1 3 0 0 3 3 3 3 von Willebrand factor type A domain FTCD PF02971.9 KFM10118.1 - 2.1e-80 267.4 0.1 3.5e-80 266.6 0.1 1.4 1 0 0 1 1 1 1 Formiminotransferase domain FTCD_N PF07837.7 KFM10118.1 - 5.5e-74 247.5 0.0 8.3e-74 246.9 0.0 1.3 1 0 0 1 1 1 1 Formiminotransferase domain, N-terminal subdomain FTCD_C PF04961.7 KFM10118.1 - 4.9e-62 208.6 1.0 7.5e-62 208.0 0.7 1.3 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase VOMI PF03762.12 KFM10119.1 - 9.4e-26 90.8 0.2 1.1e-25 90.5 0.1 1.1 1 0 0 1 1 1 1 Vitelline membrane outer layer protein I (VOMI) FAR1 PF03101.10 KFM10119.1 - 0.077 13.5 0.0 15 6.1 0.0 2.2 2 0 0 2 2 2 0 FAR1 DNA-binding domain SAC3_GANP PF03399.11 KFM10120.1 - 3e-55 186.9 3.6 5.6e-55 186.0 2.5 1.5 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KFM10120.1 - 5.3e-05 23.0 0.0 0.00016 21.4 0.0 1.8 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 RRM_6 PF14259.1 KFM10120.1 - 0.014 15.3 0.0 0.08 12.9 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFM10120.1 - 0.085 12.5 0.0 0.25 10.9 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RST PF12174.3 KFM10120.1 - 0.14 11.9 2.1 0.46 10.3 0.3 2.7 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain UPF0054 PF02130.12 KFM10121.1 - 9.1e-32 109.3 0.0 1e-31 109.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 A_deamin PF02137.13 KFM10122.1 - 2.4e-125 418.4 0.0 3.3e-125 417.9 0.0 1.2 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain dsrm PF00035.20 KFM10122.1 - 3.7e-29 101.1 0.2 2.3e-14 53.7 0.0 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif DND1_DSRM PF14709.1 KFM10122.1 - 5.6e-05 23.3 0.2 0.25 11.6 0.1 3.0 2 1 0 2 2 2 2 double strand RNA binding domain from DEAD END PROTEIN 1 SLX9 PF15341.1 KFM10123.1 - 1.9e-13 50.8 8.4 2.3e-13 50.6 5.8 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 Integrin_beta PF00362.13 KFM10124.1 - 2.8e-175 583.3 0.1 4e-175 582.7 0.1 1.2 1 0 0 1 1 1 1 Integrin, beta chain Integrin_b_cyt PF08725.6 KFM10124.1 - 5.4e-20 70.5 1.4 1.1e-19 69.4 1.0 1.6 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain Integrin_B_tail PF07965.7 KFM10124.1 - 4.5e-17 62.2 6.9 4.5e-17 62.2 4.8 4.1 3 1 0 4 4 4 1 Integrin beta tail domain EGF_2 PF07974.8 KFM10124.1 - 0.00012 22.1 101.1 0.01 15.9 11.1 7.2 6 1 1 7 7 7 4 EGF-like domain hEGF PF12661.2 KFM10124.1 - 0.0017 18.3 1.8 0.0017 18.3 1.3 6.8 7 1 0 7 7 7 2 Human growth factor-like EGF FAD_binding_3 PF01494.14 KFM10125.1 - 4.1e-20 72.1 0.0 9.6e-20 70.9 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KFM10125.1 - 8e-06 25.7 0.4 2.9e-05 23.9 0.3 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFM10125.1 - 8e-05 21.7 0.4 0.00017 20.6 0.3 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.5 KFM10125.1 - 0.00014 20.8 0.1 0.067 12.0 0.0 2.4 2 1 0 2 2 2 2 Squalene epoxidase Pyr_redox PF00070.22 KFM10125.1 - 0.00027 21.2 0.2 0.00059 20.1 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KFM10125.1 - 0.0011 18.7 0.1 0.0017 18.0 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KFM10125.1 - 0.045 13.1 0.0 0.067 12.5 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.1 KFM10125.1 - 0.055 13.7 0.0 0.098 12.9 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_2 PF00890.19 KFM10125.1 - 0.081 11.7 0.3 0.11 11.2 0.2 1.1 1 0 0 1 1 1 0 FAD binding domain DUF4587 PF15248.1 KFM10126.1 - 7.5e-31 106.5 12.4 7.5e-31 106.5 8.6 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4587) APH PF01636.18 KFM10126.1 - 0.24 11.1 5.2 1.2 8.8 3.6 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family HAUS-augmin3 PF14932.1 KFM10127.1 - 0.0054 15.9 7.9 0.0054 15.9 5.5 2.0 1 1 1 2 2 2 1 HAUS augmin-like complex subunit 3 Clr5 PF14420.1 KFM10127.1 - 0.52 10.2 6.3 0.17 11.7 1.2 2.1 2 0 0 2 2 2 0 Clr5 domain DUF445 PF04286.7 KFM10127.1 - 0.76 9.2 11.6 0.91 8.9 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF3355 PF11835.3 KFM10127.1 - 0.97 9.2 3.1 1.2 8.8 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3355) DUF3496 PF12001.3 KFM10127.1 - 3.3 7.9 10.3 0.88 9.8 2.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3496) SAE2 PF08573.5 KFM10127.1 - 7.9 7.2 7.4 57 4.5 5.1 2.2 1 1 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus PACT_coil_coil PF10495.4 KFM10128.1 - 5.4e-34 115.9 0.1 7.1e-34 115.5 0.1 1.2 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein DUF1136 PF06582.7 KFM10129.1 - 0.065 12.9 0.7 0.15 11.7 0.5 1.6 1 0 0 1 1 1 0 Repeat of unknown function (DUF1136) AMP-binding PF00501.23 KFM10130.1 - 4.3e-77 259.2 1.2 6e-49 166.5 0.2 2.4 2 0 0 2 2 2 2 AMP-binding enzyme DMAP_binding PF06464.6 KFM10130.1 - 2.2e-11 44.3 2.5 4.5e-11 43.3 1.7 1.5 1 0 0 1 1 1 1 DMAP1-binding Domain Macoilin PF09726.4 KFM10130.1 - 9.4 4.3 9.5 14 3.8 6.6 1.1 1 0 0 1 1 1 0 Transmembrane protein zf-H2C2_2 PF13465.1 KFM10131.1 - 1.7e-54 179.5 33.1 1.3e-09 37.8 0.3 6.2 6 0 0 6 6 6 6 Zinc-finger double domain zf-C2H2 PF00096.21 KFM10131.1 - 1.7e-36 122.3 36.2 3.5e-06 27.0 0.8 7.1 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM10131.1 - 2e-25 87.1 34.6 0.00013 22.0 0.4 7.1 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM10131.1 - 5.4e-11 42.3 13.8 0.028 14.5 0.1 6.2 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFM10131.1 - 4.8e-10 38.9 28.0 0.02 14.8 0.2 7.1 7 1 0 7 7 6 3 C2H2-type zinc finger XPA_N PF01286.13 KFM10131.1 - 6.3e-06 25.7 15.8 0.98 9.1 0.1 5.8 6 0 0 6 6 6 2 XPA protein N-terminal zf-CHY PF05495.7 KFM10131.1 - 1e-05 25.5 9.9 0.016 15.3 0.6 2.8 2 2 0 2 2 2 2 CHY zinc finger Prok-RING_1 PF14446.1 KFM10131.1 - 4.3e-05 23.1 7.7 9.6 6.0 0.0 5.8 6 0 0 6 6 6 0 Prokaryotic RING finger family 1 FdhE PF04216.7 KFM10131.1 - 4.7e-05 23.2 14.9 0.0026 17.5 1.0 3.0 1 1 1 2 2 2 2 Protein involved in formate dehydrogenase formation C1_4 PF07975.7 KFM10131.1 - 8.8e-05 22.4 13.2 0.32 11.0 0.1 4.7 1 1 4 5 5 5 1 TFIIH C1-like domain zf-met PF12874.2 KFM10131.1 - 0.0001 22.3 27.1 0.11 12.7 0.7 5.7 6 0 0 6 6 5 2 Zinc-finger of C2H2 type zf-Di19 PF05605.7 KFM10131.1 - 0.00014 21.8 20.7 0.061 13.4 1.5 3.8 2 2 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding FYVE PF01363.16 KFM10131.1 - 0.00014 21.6 19.0 0.032 14.1 0.7 4.1 1 1 1 3 3 3 1 FYVE zinc finger C1_1 PF00130.17 KFM10131.1 - 0.00014 21.4 15.0 0.098 12.3 0.7 4.3 1 1 3 5 5 5 3 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.5 KFM10131.1 - 0.00032 20.5 21.5 0.95 9.4 0.1 5.8 4 2 1 5 5 5 1 Zinc ribbon domain zinc_ribbon_4 PF13717.1 KFM10131.1 - 0.0015 18.1 14.5 3.1 7.5 0.0 5.3 6 0 0 6 6 5 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 KFM10131.1 - 0.0016 17.9 16.0 2 8.0 0.0 5.4 6 0 0 6 6 5 1 zinc-ribbon domain Elf1 PF05129.8 KFM10131.1 - 0.0019 17.8 12.5 0.15 11.7 0.3 4.0 1 1 3 4 4 4 1 Transcription elongation factor Elf1 like zf-RING_3 PF14369.1 KFM10131.1 - 0.0028 17.6 9.8 10 6.2 0.0 5.5 6 0 0 6 6 6 0 zinc-finger GAGA PF09237.6 KFM10131.1 - 0.0063 16.0 9.3 0.67 9.5 0.2 4.2 2 2 3 5 5 5 1 GAGA factor CpXC PF14353.1 KFM10131.1 - 0.019 14.9 13.9 7.6 6.5 0.0 5.4 3 1 2 5 5 5 0 CpXC protein BolA PF01722.13 KFM10131.1 - 0.021 14.7 2.4 0.65 9.9 0.1 3.2 1 1 3 4 4 4 0 BolA-like protein LIM PF00412.17 KFM10131.1 - 0.037 14.1 14.3 3.1 7.9 0.8 4.8 3 1 2 5 5 5 0 LIM domain Mut7-C PF01927.11 KFM10131.1 - 0.047 13.6 13.5 5.1 7.0 3.3 4.6 1 1 1 2 2 2 0 Mut7-C RNAse domain zf-met2 PF12907.2 KFM10131.1 - 0.061 13.2 10.5 5.4 7.0 0.0 4.9 5 0 0 5 5 4 0 Zinc-binding RRN7 PF11781.3 KFM10131.1 - 0.069 12.6 7.9 15 5.1 0.0 4.8 5 0 0 5 5 5 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C2HC_2 PF13913.1 KFM10131.1 - 0.071 12.7 0.1 0.071 12.7 0.1 5.6 6 0 0 6 6 6 0 zinc-finger of a C2HC-type DUF3268 PF11672.3 KFM10131.1 - 0.13 12.3 8.2 6.1 6.9 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3268) DZR PF12773.2 KFM10131.1 - 0.19 11.5 14.6 1.8e+02 2.0 0.1 4.2 1 1 1 2 2 1 0 Double zinc ribbon DUF2225 PF09986.4 KFM10131.1 - 0.19 11.1 5.4 6.3 6.1 0.0 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) PHF5 PF03660.9 KFM10131.1 - 0.24 11.4 4.8 1.1 9.3 0.3 2.8 1 1 1 2 2 2 0 PHF5-like protein UPF0515 PF15135.1 KFM10131.1 - 0.25 10.3 4.0 0.11 11.5 0.2 2.2 1 1 0 2 2 2 0 Uncharacterised protein UPF0515 zf-AN1 PF01428.11 KFM10131.1 - 0.26 11.1 24.4 1.7 8.6 0.1 5.9 4 1 2 6 6 6 0 AN1-like Zinc finger SprT-like PF10263.4 KFM10131.1 - 0.44 10.1 10.4 32 4.1 7.2 3.2 1 1 0 1 1 1 0 SprT-like family zf-NADH-PPase PF09297.6 KFM10131.1 - 0.88 9.1 0.0 0.88 9.1 0.0 3.7 4 0 0 4 4 4 0 NADH pyrophosphatase zinc ribbon domain HypA PF01155.14 KFM10131.1 - 0.98 9.1 12.2 4.8e+03 -2.8 8.5 4.0 1 1 0 1 1 0 0 Hydrogenase expression/synthesis hypA family zf-Sec23_Sec24 PF04810.10 KFM10131.1 - 1 9.0 0.0 1 9.0 0.0 4.5 6 0 0 6 6 6 0 Sec23/Sec24 zinc finger zf-LYAR PF08790.6 KFM10131.1 - 1.1 8.9 11.1 5 6.9 0.0 4.5 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger zf-C2H2_2 PF12756.2 KFM10131.1 - 1.3 9.2 19.6 4.2 7.5 0.1 5.1 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) Zn_Tnp_IS1595 PF12760.2 KFM10131.1 - 1.4 8.8 27.7 2.6 7.9 2.8 4.6 1 1 3 4 4 4 0 Transposase zinc-ribbon domain zf-RING_5 PF14634.1 KFM10131.1 - 2.5 7.8 20.2 5.7 6.7 1.2 5.0 4 2 0 4 4 4 0 zinc-RING finger domain zf-trcl PF13451.1 KFM10131.1 - 2.6 7.7 17.2 8.8 6.0 0.2 5.3 6 0 0 6 6 6 0 Probable zinc-binding domain Ribosomal_L37ae PF01780.14 KFM10131.1 - 2.9 7.8 13.1 14 5.6 0.4 4.9 1 1 4 5 5 5 0 Ribosomal L37ae protein family ZZ PF00569.12 KFM10131.1 - 3.9 7.0 10.1 6.3 6.4 0.2 4.6 5 0 0 5 5 5 0 Zinc finger, ZZ type zf-HIT PF04438.11 KFM10131.1 - 5.9 6.6 22.3 4 7.1 0.3 5.4 6 0 0 6 6 6 0 HIT zinc finger zf-C3HC4_3 PF13920.1 KFM10131.1 - 6.7 6.4 14.3 2.3 7.9 0.3 4.2 3 2 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) GF_recep_IV PF14843.1 KFM10131.1 - 7.1 6.2 8.0 1.3e+02 2.1 4.2 2.7 1 1 0 1 1 1 0 Growth factor receptor domain IV DUF2175 PF09943.4 KFM10131.1 - 7.2 6.7 6.6 83 3.3 0.0 4.4 6 0 0 6 6 5 0 Uncharacterized protein conserved in archaea (DUF2175) YhfH PF14149.1 KFM10131.1 - 8.5 6.2 11.2 23 4.8 0.1 4.4 5 0 0 5 5 5 0 YhfH-like protein TFIIS_C PF01096.13 KFM10131.1 - 9.3 5.9 20.9 2.1 8.0 0.3 5.5 6 0 0 6 6 6 0 Transcription factor S-II (TFIIS) zf-ISL3 PF14690.1 KFM10131.1 - 9.8 6.2 19.1 17 5.5 0.1 5.6 5 1 1 6 6 6 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 S_100 PF01023.14 KFM10132.1 - 1.9e-20 71.8 1.8 3e-20 71.2 1.2 1.3 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_7 PF13499.1 KFM10132.1 - 0.00028 20.9 0.9 0.00039 20.4 0.6 1.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KFM10132.1 - 0.00085 18.4 0.4 0.00085 18.4 0.2 2.4 3 0 0 3 3 3 1 EF hand EF-hand_4 PF12763.2 KFM10132.1 - 0.018 14.7 0.7 0.022 14.4 0.5 1.3 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Leuk-A4-hydro_C PF09127.6 KFM10132.1 - 0.035 13.7 0.1 0.046 13.3 0.1 1.1 1 0 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal EF-hand_8 PF13833.1 KFM10132.1 - 0.052 13.1 1.3 0.088 12.4 0.9 1.4 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.1 KFM10132.1 - 0.053 13.4 0.6 1.9 8.5 0.0 2.6 2 1 0 2 2 2 0 EF-hand domain ALIX_LYPXL_bnd PF13949.1 KFM10133.1 - 0.01 14.8 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV SRCR PF00530.13 KFM10134.1 - 4.2e-90 296.4 30.6 1.3e-28 99.2 1.0 4.3 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain Lysyl_oxidase PF01186.12 KFM10134.1 - 5.5e-64 215.5 1.8 5.5e-64 215.5 1.2 2.1 3 0 0 3 3 3 1 Lysyl oxidase SRCR_2 PF15494.1 KFM10134.1 - 1.5e-16 60.4 16.8 0.00014 22.0 0.3 4.7 4 1 0 4 4 4 4 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.5 KFM10134.1 - 0.0014 18.8 4.5 0.64 10.2 0.0 4.2 3 1 1 4 4 4 1 Hepsin, SRCR CUE PF02845.11 KFM10135.1 - 1.6e-09 37.0 0.0 3e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 CUE domain BNIP3 PF06553.7 KFM10136.1 - 1.3e-19 70.3 0.0 1.7e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 BNIP3 DOCK-C2 PF14429.1 KFM10137.1 - 6.6e-49 166.0 0.0 1.4e-48 164.9 0.0 1.6 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 KFM10137.1 - 5.7e-41 139.7 0.2 2.7e-40 137.5 0.0 2.3 2 0 0 2 2 2 1 Dedicator of cytokinesis Cut8_M PF14483.1 KFM10137.1 - 0.015 15.0 3.7 0.073 12.8 0.0 3.5 4 0 0 4 4 4 0 Cut8 dimerisation domain Nop14 PF04147.7 KFM10137.1 - 0.25 9.2 0.3 0.41 8.4 0.2 1.2 1 0 0 1 1 1 0 Nop14-like family HA2 PF04408.18 KFM10138.1 - 1.1e-22 79.9 0.1 2.3e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KFM10138.1 - 1.2e-12 47.6 0.0 2.2e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 KFM10138.1 - 4.5e-07 30.0 0.0 9.9e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFM10138.1 - 0.00059 19.5 0.0 0.0023 17.6 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 KFM10138.1 - 0.006 16.1 0.0 0.013 15.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFM10138.1 - 0.0083 16.1 3.0 0.034 14.1 1.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.1 KFM10138.1 - 0.015 14.9 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KFM10138.1 - 0.057 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KFM10138.1 - 0.076 12.9 0.0 0.89 9.4 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KFM10138.1 - 0.077 13.8 0.1 0.21 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KFM10138.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sushi PF00084.15 KFM10139.1 - 5.3e-150 487.8 152.6 7.4e-11 42.2 0.8 20.1 20 0 0 20 20 20 19 Sushi domain (SCR repeat) Sushi PF00084.15 KFM10140.1 - 1.6e-51 172.4 68.4 1.9e-09 37.7 1.9 9.4 9 0 0 9 9 9 9 Sushi domain (SCR repeat) Sushi_2 PF09014.5 KFM10140.1 - 8.6e-05 22.2 23.1 0.0024 17.5 0.5 6.5 5 3 1 6 6 6 2 Beta-2-glycoprotein-1 fifth domain cEGF PF12662.2 KFM10140.1 - 0.71 9.5 16.3 4.8 6.9 0.3 5.5 5 0 0 5 5 5 0 Complement Clr-like EGF-like zf-H2C2_2 PF13465.1 KFM10141.1 - 2e-53 176.1 128.0 4.2e-07 29.9 0.5 15.2 16 0 0 16 16 16 13 Zinc-finger double domain zf-C2H2 PF00096.21 KFM10141.1 - 1.3e-47 157.2 135.7 6e-05 23.1 2.3 14.7 14 0 0 14 14 14 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM10141.1 - 2.3e-34 115.1 127.4 0.00096 19.3 0.6 15.0 15 0 0 15 15 15 13 C2H2-type zinc finger BTB PF00651.26 KFM10141.1 - 2.8e-21 75.5 0.7 8.3e-21 74.0 0.5 1.9 1 0 0 1 1 1 1 BTB/POZ domain zf-met PF12874.2 KFM10141.1 - 1.1e-09 38.0 87.4 0.00035 20.6 1.0 13.9 14 0 0 14 14 14 5 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFM10141.1 - 1e-08 34.7 103.6 0.00052 19.8 0.7 13.7 14 0 0 14 14 14 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM10141.1 - 7.2e-08 32.3 86.7 0.038 14.1 1.7 14.1 14 0 0 14 14 14 7 Zinc-finger double-stranded RNA-binding GAGA PF09237.6 KFM10141.1 - 0.0088 15.6 15.8 4.1 7.0 0.1 6.6 3 2 3 6 6 6 3 GAGA factor zf-C2H2_2 PF12756.2 KFM10141.1 - 0.026 14.6 83.1 0.031 14.3 0.1 13.3 3 1 8 12 12 12 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 KFM10141.1 - 0.076 12.6 0.2 0.066 12.8 1.3 12.2 14 0 0 14 14 14 0 zinc-finger of a C2HC-type EGF PF00008.22 KFM10142.1 - 1.2e-96 315.9 279.9 4.9e-08 32.7 2.4 19.9 19 1 0 19 19 19 18 EGF-like domain Laminin_G_2 PF02210.19 KFM10142.1 - 1.9e-51 173.4 1.2 1e-19 70.7 0.0 3.4 3 0 0 3 3 3 3 Laminin G domain Laminin_G_1 PF00054.18 KFM10142.1 - 7.1e-40 136.0 0.2 6.4e-15 55.3 0.0 3.8 4 0 0 4 4 4 3 Laminin G domain EGF_CA PF07645.10 KFM10142.1 - 2.9e-20 71.9 274.6 1.1e-05 25.2 4.3 20.0 15 4 5 20 20 20 14 Calcium-binding EGF domain EGF_2 PF07974.8 KFM10142.1 - 1.8e-17 63.2 305.6 0.001 19.1 5.8 19.6 19 0 0 19 19 19 15 EGF-like domain hEGF PF12661.2 KFM10142.1 - 4.2e-17 60.9 174.3 0.0022 17.9 2.6 18.4 18 0 0 18 18 18 10 Human growth factor-like EGF Laminin_G_3 PF13385.1 KFM10142.1 - 6.5e-07 29.7 0.0 0.025 14.8 0.0 3.2 3 0 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily EGF_3 PF12947.2 KFM10142.1 - 0.00026 20.9 253.6 0.004 17.0 1.6 19.9 17 2 2 19 19 19 13 EGF domain Polysacc_lyase PF14099.1 KFM10142.1 - 0.15 11.7 0.0 0.53 9.9 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide lyase DENN PF02141.16 KFM10143.1 - 1.1e-48 165.3 3.6 2e-48 164.5 2.5 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 KFM10143.1 - 7.5e-19 67.5 0.0 2.1e-18 66.1 0.0 1.8 1 0 0 1 1 1 1 dDENN domain SPA PF08616.5 KFM10143.1 - 0.097 12.3 0.2 0.23 11.1 0.2 1.6 1 0 0 1 1 1 0 Stabilization of polarity axis Pkinase PF00069.20 KFM10144.1 - 2.1e-67 227.0 0.0 2.6e-67 226.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM10144.1 - 1.9e-48 164.8 0.0 2.3e-48 164.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM10144.1 - 2.5e-08 33.2 0.0 3.2e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PIP49_C PF12260.3 KFM10144.1 - 0.0093 15.3 0.2 0.43 9.9 0.1 2.2 2 0 0 2 2 2 1 Protein-kinase domain of FAM69 Kdo PF06293.9 KFM10144.1 - 0.018 14.1 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RMMBL PF07521.7 KFM10144.1 - 0.018 14.8 0.1 0.88 9.4 0.0 2.6 2 0 0 2 2 2 0 RNA-metabolising metallo-beta-lactamase V-ATPase_G PF03179.10 KFM10145.1 - 2.5e-34 117.6 11.9 2.9e-34 117.5 8.2 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit VWA_N PF08399.6 KFM10145.1 - 0.014 15.9 0.3 0.018 15.6 0.2 1.1 1 0 0 1 1 1 0 VWA N-terminal FdhE PF04216.7 KFM10145.1 - 0.043 13.5 1.3 0.047 13.4 0.9 1.0 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation DUF2072 PF09845.4 KFM10145.1 - 0.065 13.1 3.6 0.081 12.8 2.5 1.1 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Gti1_Pac2 PF09729.4 KFM10145.1 - 0.066 13.0 4.6 0.083 12.7 3.2 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family TraC_F_IV PF11130.3 KFM10145.1 - 0.089 12.2 0.4 0.11 11.9 0.2 1.2 1 0 0 1 1 1 0 F pilus assembly Type-IV secretion system for plasmid transfer HrpE PF06188.7 KFM10145.1 - 0.1 12.3 4.6 0.13 11.9 3.2 1.2 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E DUF3552 PF12072.3 KFM10145.1 - 0.1 11.7 14.8 0.19 10.9 10.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) GA PF01468.12 KFM10145.1 - 0.14 12.3 7.5 0.15 12.2 2.7 2.5 1 1 2 3 3 3 0 GA module LPP20 PF02169.11 KFM10145.1 - 0.34 11.0 2.2 0.43 10.7 1.6 1.3 1 0 0 1 1 1 0 LPP20 lipoprotein Cor1 PF04803.7 KFM10145.1 - 0.38 10.5 10.4 10 5.8 7.2 2.1 1 1 0 1 1 1 0 Cor1/Xlr/Xmr conserved region Exonuc_VII_L PF02601.10 KFM10145.1 - 0.5 9.4 8.2 0.56 9.3 5.7 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Baculo_p24 PF05073.7 KFM10145.1 - 0.67 9.5 4.5 0.88 9.1 3.1 1.3 1 1 0 1 1 1 0 Baculovirus P24 capsid protein CENP-Q PF13094.1 KFM10145.1 - 0.87 9.5 10.0 1.1 9.3 6.9 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF883 PF05957.8 KFM10145.1 - 0.99 9.8 7.8 1.7 9.0 3.5 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF106 PF01956.11 KFM10145.1 - 1 8.8 6.3 1.4 8.4 4.4 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 ATP-synt_B PF00430.13 KFM10145.1 - 1.5 8.6 13.7 3.9 7.2 9.5 1.7 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) Muted PF14942.1 KFM10145.1 - 2.1 8.2 12.8 1.4 8.7 5.5 2.0 1 1 2 3 3 3 0 Organelle biogenesis, Muted-like protein DUF1542 PF07564.6 KFM10145.1 - 2.2 8.3 7.5 1.3 9.0 3.6 1.9 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1542) Hormone_recep PF00104.25 KFM10146.1 - 9.2e-33 113.0 4.4 1.4e-32 112.4 3.1 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFM10146.1 - 2e-32 111.1 12.0 3.4e-32 110.4 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) zf-H2C2_2 PF13465.1 KFM10147.1 - 1.9e-21 75.2 20.5 2e-06 27.7 0.1 4.7 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.21 KFM10147.1 - 3.7e-12 45.8 36.2 0.0037 17.5 0.7 5.0 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM10147.1 - 4.7e-08 32.8 29.7 0.014 15.7 3.1 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger RRN7 PF11781.3 KFM10147.1 - 0.38 10.2 3.1 30 4.2 0.1 3.5 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 GAGA PF09237.6 KFM10147.1 - 0.85 9.2 9.2 0.14 11.8 1.3 2.9 1 1 1 3 3 3 0 GAGA factor zf-RING_3 PF14369.1 KFM10147.1 - 0.87 9.6 4.0 5.2 7.1 0.0 3.2 3 0 0 3 3 3 0 zinc-finger zf-C2H2_6 PF13912.1 KFM10147.1 - 7.2 6.6 24.3 0.16 11.9 0.9 5.0 5 0 0 5 5 5 0 C2H2-type zinc finger Kinesin PF00225.18 KFM10148.1 - 2.7e-108 361.6 0.1 2.7e-108 361.6 0.1 2.0 2 0 0 2 2 2 1 Kinesin motor domain FHA PF00498.21 KFM10148.1 - 2.1e-09 37.3 0.2 4.9e-09 36.1 0.1 1.7 1 0 0 1 1 1 1 FHA domain DEAD PF00270.24 KFM10149.1 - 4.3e-42 143.4 0.8 4.3e-42 143.4 0.6 2.3 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFM10149.1 - 2.3e-20 72.2 0.1 6.9e-20 70.6 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-HIT PF04438.11 KFM10149.1 - 2.2e-08 33.5 1.9 3.8e-08 32.8 1.3 1.4 1 0 0 1 1 1 1 HIT zinc finger SecA_DEAD PF07517.9 KFM10149.1 - 0.003 16.8 0.7 0.23 10.7 0.0 2.6 3 0 0 3 3 3 1 SecA DEAD-like domain ResIII PF04851.10 KFM10149.1 - 0.0085 15.9 0.0 0.051 13.3 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 KFM10149.1 - 0.02 14.1 0.8 0.91 8.7 0.0 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA PF00004.24 KFM10149.1 - 0.039 14.1 0.4 0.19 11.9 0.2 2.2 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) CAMSAP_CKK PF08683.6 KFM10151.1 - 1.1e-47 160.7 0.1 2.5e-47 159.6 0.1 1.6 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated CH PF00307.26 KFM10151.1 - 1.1e-36 125.1 1.8 4e-36 123.3 0.9 2.3 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFM10151.1 - 6.8e-35 118.5 1.7 2.5e-34 116.7 1.2 2.1 1 0 0 1 1 1 1 CAMSAP CH domain WD40 PF00400.27 KFM10152.1 - 2.1e-42 141.5 13.2 1.1e-08 34.5 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat MCLC PF05934.6 KFM10153.1 - 1.9e-173 577.7 4.9 2.2e-173 577.5 3.4 1.0 1 0 0 1 1 1 1 Mid-1-related chloride channel (MCLC) SPC25 PF06703.6 KFM10153.1 - 0.18 11.3 4.2 0.11 12.0 1.4 1.8 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF4149 PF13664.1 KFM10153.1 - 0.75 9.8 6.5 0.35 10.9 1.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) PAP2 PF01569.16 KFM10153.1 - 6.9 6.3 8.5 1.8 8.2 3.3 1.9 2 0 0 2 2 2 0 PAP2 superfamily GoLoco PF02188.12 KFM10154.1 - 9.8e-39 129.8 28.4 1.5e-10 40.0 2.3 4.5 4 0 0 4 4 4 4 GoLoco motif TPR_12 PF13424.1 KFM10154.1 - 1.8e-38 130.3 31.0 1.9e-10 40.4 3.6 6.0 2 2 4 7 7 7 7 Tetratricopeptide repeat TPR_1 PF00515.23 KFM10154.1 - 7.4e-36 120.3 31.2 8.4e-07 28.3 0.3 8.3 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_7 PF13176.1 KFM10154.1 - 1.1e-28 96.7 21.2 2e-05 24.0 0.2 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.12 KFM10154.1 - 1.6e-21 74.4 28.7 0.00019 21.1 0.4 8.2 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.1 KFM10154.1 - 1.6e-21 75.7 25.2 4.1e-07 29.5 0.6 5.6 4 2 2 6 6 6 6 TPR repeat TPR_10 PF13374.1 KFM10154.1 - 7.5e-15 54.2 25.7 0.038 13.9 0.3 8.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 KFM10154.1 - 6.6e-14 50.5 27.5 0.00029 20.3 0.2 8.6 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 KFM10154.1 - 1.6e-08 34.4 5.4 0.34 11.6 0.1 7.0 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_4 PF07721.9 KFM10154.1 - 2.3e-08 33.6 0.1 0.52 10.8 0.1 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFM10154.1 - 2e-06 28.3 19.4 0.0047 17.5 0.6 6.1 4 2 2 6 6 6 3 Tetratricopeptide repeat Rapsyn_N PF10579.4 KFM10154.1 - 3.4e-06 26.7 1.6 2.8 7.8 0.0 5.4 2 2 4 6 6 6 2 Rapsyn N-terminal myristoylation and linker region TPR_17 PF13431.1 KFM10154.1 - 1e-05 25.3 19.5 2.9 8.3 0.1 7.8 7 1 1 8 8 7 2 Tetratricopeptide repeat Apc3 PF12895.2 KFM10154.1 - 0.00019 21.4 14.6 0.18 11.9 2.7 5.2 3 1 3 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KFM10154.1 - 0.00078 19.7 6.4 5.4 7.6 0.2 6.3 7 0 0 7 7 6 1 Tetratricopeptide repeat RPN7 PF10602.4 KFM10154.1 - 0.17 11.2 1.8 0.9 8.8 0.1 2.8 2 2 0 3 3 3 0 26S proteasome subunit RPN7 UreE_C PF05194.7 KFM10154.1 - 8.4 6.5 8.9 11 6.1 0.1 3.6 4 1 1 5 5 4 0 UreE urease accessory protein, C-terminal domain Sec1 PF00995.18 KFM10155.1 - 2.1e-135 452.5 2.9 2.4e-135 452.3 2.0 1.0 1 0 0 1 1 1 1 Sec1 family DDE_Tnp_IS1595 PF12762.2 KFM10155.1 - 0.12 12.2 0.0 0.49 10.2 0.0 2.0 2 0 0 2 2 2 0 ISXO2-like transposase domain fn3 PF00041.16 KFM10156.1 - 6.9e-33 112.6 14.7 2.3e-06 27.6 0.1 9.6 8 3 0 8 8 8 5 Fibronectin type III domain Y_Y_Y PF07495.8 KFM10156.1 - 0.0031 17.2 0.1 0.061 13.0 0.1 3.1 3 0 0 3 3 3 1 Y_Y_Y domain Cna_B PF05738.8 KFM10156.1 - 0.0037 16.9 0.4 1.5 8.6 0.0 3.5 3 0 0 3 3 3 1 Cna protein B-type domain DUF2369 PF10179.4 KFM10156.1 - 0.012 14.7 8.6 0.32 10.0 0.0 5.1 6 1 0 7 7 7 0 Uncharacterised conserved protein (DUF2369) PRP38 PF03371.10 KFM10157.1 - 3.5e-55 186.2 0.0 4.6e-55 185.8 0.0 1.1 1 0 0 1 1 1 1 PRP38 family Methyltransf_23 PF13489.1 KFM10158.1 - 2e-05 24.3 0.0 3.4e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFM10158.1 - 0.0073 16.7 0.0 0.015 15.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NT-C2 PF10358.4 KFM10159.1 - 1.5e-16 60.1 0.0 2.2e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Mito_carr PF00153.22 KFM10160.1 - 5.7e-77 253.5 5.4 4.4e-27 93.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 KFM10160.1 - 5.1e-16 56.6 4.6 1.7e-06 26.9 0.3 3.7 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 KFM10160.1 - 5.8e-15 55.1 1.3 6.4e-08 32.6 0.0 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KFM10160.1 - 1.1e-13 49.7 3.1 0.00044 19.9 0.0 3.8 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.1 KFM10160.1 - 5.2e-12 44.5 2.5 2.1e-05 23.6 0.3 3.5 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 KFM10160.1 - 7.2e-10 38.3 1.9 5.9e-06 25.8 0.1 3.3 2 1 1 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFM10160.1 - 3.2e-05 23.9 0.6 0.0059 16.6 0.1 2.3 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 KFM10160.1 - 0.00018 21.1 1.3 0.41 10.3 0.1 3.3 2 1 1 3 3 3 3 EF hand EF-hand_9 PF14658.1 KFM10160.1 - 0.0029 17.4 0.0 0.14 12.0 0.0 2.8 4 0 0 4 4 3 1 EF-hand domain EF-hand_4 PF12763.2 KFM10160.1 - 0.0081 15.8 3.2 0.15 11.8 0.1 2.5 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand DUF2340 PF10209.4 KFM10160.1 - 0.032 14.3 0.0 0.15 12.2 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2340) RhoGEF PF00621.15 KFM10161.1 - 3.2e-39 134.6 8.7 7.8e-39 133.4 6.0 1.7 1 0 0 1 1 1 1 RhoGEF domain SH3_2 PF07653.12 KFM10161.1 - 8.1e-28 95.6 0.0 1.6e-14 53.0 0.0 2.8 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.1 KFM10161.1 - 1.6e-19 69.1 0.1 1.4e-12 47.0 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KFM10161.1 - 2.9e-17 61.7 0.1 1.6e-13 49.8 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH2 PF00017.19 KFM10161.1 - 1.2e-15 57.0 0.5 7.1e-15 54.5 0.4 2.4 1 0 0 1 1 1 1 SH2 domain C1_1 PF00130.17 KFM10161.1 - 9.9e-10 37.9 4.7 1.9e-09 37.0 3.2 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.24 KFM10161.1 - 2.3e-07 30.9 0.1 5.2e-07 29.8 0.1 1.6 1 0 0 1 1 1 1 PH domain Filamin PF00630.14 KFM10161.1 - 0.00076 20.0 0.0 0.0063 17.0 0.0 2.2 2 0 0 2 2 2 1 Filamin/ABP280 repeat CAMSAP_CH PF11971.3 KFM10161.1 - 0.012 15.2 1.3 0.099 12.2 0.0 2.6 2 0 0 2 2 2 0 CAMSAP CH domain Prok-RING_1 PF14446.1 KFM10161.1 - 0.014 15.1 1.7 0.032 13.9 1.2 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 C1_2 PF03107.11 KFM10161.1 - 0.026 14.6 2.3 0.088 12.9 1.6 2.0 1 0 0 1 1 1 0 C1 domain DUF2247 PF10004.4 KFM10161.1 - 1.1 8.9 6.1 0.23 11.1 0.1 2.7 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2247) Laminin_N PF00055.12 KFM10162.1 - 2.8e-30 105.0 0.7 2.8e-30 105.0 0.5 2.4 2 1 0 2 2 2 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.19 KFM10162.1 - 1.3e-22 79.4 63.4 1.6e-08 34.3 7.9 4.8 3 1 1 4 4 4 3 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 KFM10162.1 - 0.00099 19.2 10.7 0.00099 19.2 7.4 7.5 6 2 2 8 8 8 1 EGF-like domain EGF PF00008.22 KFM10162.1 - 0.0093 15.9 10.2 0.0093 15.9 7.1 6.1 6 2 0 6 6 6 1 EGF-like domain hEGF PF12661.2 KFM10162.1 - 0.013 15.5 2.2 0.013 15.5 1.5 6.3 7 0 0 7 7 7 0 Human growth factor-like EGF Alpha-amylase PF00128.19 KFM10163.1 - 3.5e-20 72.6 0.0 6.5e-20 71.7 0.0 1.3 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 KFM10163.1 - 3.3e-14 52.7 0.7 7.8e-14 51.5 0.2 1.9 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 KFM10164.1 - 4.8e-23 82.0 0.0 6.6e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 KFM10164.1 - 4e-12 46.0 0.3 1.2e-11 44.5 0.1 1.9 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain RRM_6 PF14259.1 KFM10165.1 - 4.5e-12 45.7 0.6 4.9e-07 29.6 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFM10165.1 - 2.1e-11 43.2 0.2 8e-07 28.6 0.2 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM10165.1 - 9.1e-09 35.0 0.1 0.0032 17.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Collagen PF01391.13 KFM10166.1 - 5.8e-162 525.3 687.7 5e-09 35.5 18.2 22.3 3 1 14 17 17 17 13 Collagen triple helix repeat (20 copies) COLFI PF01410.13 KFM10166.1 - 9.1e-85 283.4 0.1 1.2e-84 283.0 0.1 1.2 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Laminin_G_2 PF02210.19 KFM10166.1 - 6.6e-12 45.5 0.0 1.2e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_3 PF13385.1 KFM10166.1 - 3e-07 30.7 0.0 5.4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_1 PF00054.18 KFM10166.1 - 0.0023 17.9 0.0 0.0047 16.9 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain OLF PF02191.11 KFM10167.1 - 9e-92 306.8 8.4 1.3e-91 306.3 5.8 1.2 1 0 0 1 1 1 1 Olfactomedin-like domain Noelin-1 PF12308.3 KFM10167.1 - 1.3e-50 169.3 2.7 1.3e-50 169.3 1.9 2.1 3 0 0 3 3 3 1 Neurogenesis glycoprotein CBM_5_12_2 PF14600.1 KFM10167.1 - 0.049 13.2 1.1 0.98 9.1 0.0 2.7 2 0 0 2 2 2 0 Cellulose-binding domain DUF1978 PF09321.5 KFM10167.1 - 0.09 12.2 4.3 0.14 11.5 1.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1978) Phage_head_chap PF11113.3 KFM10167.1 - 1 9.3 3.7 25 4.8 0.0 3.5 3 0 0 3 3 3 0 Head assembly gene product DUF1664 PF07889.7 KFM10167.1 - 1.7 8.4 6.6 4.3 7.1 1.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Aldo_ket_red PF00248.16 KFM10168.1 - 9.3e-61 205.1 0.0 1.2e-60 204.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TP_methylase PF00590.15 KFM10169.1 - 1.6e-21 76.9 0.0 3.6e-21 75.8 0.0 1.5 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Cation_efflux PF01545.16 KFM10170.1 - 1.5e-58 198.1 3.4 1.9e-58 197.8 2.3 1.0 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 KFM10170.1 - 6.3 5.7 27.2 23 3.8 18.4 2.0 1 1 0 1 1 1 0 ZIP Zinc transporter DSPn PF14671.1 KFM10171.1 - 4.8e-60 201.6 2.5 2.5e-59 199.3 1.0 2.4 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 KFM10171.1 - 8.6e-15 54.4 0.4 2.9e-14 52.7 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 KFM10171.1 - 3.9e-06 26.9 0.0 7.2e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 KFM10171.1 - 8.1e-06 25.3 0.0 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KFM10171.1 - 0.00054 20.2 0.0 0.0013 18.9 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family 7tm_1 PF00001.16 KFM10172.1 - 4.7e-19 68.5 0.4 5.7e-19 68.2 0.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 KFM10172.1 - 1e-07 31.3 0.5 1.4e-07 30.9 0.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.4 KFM10172.1 - 0.003 16.7 1.1 0.0049 16.0 0.8 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx I-set PF07679.11 KFM10173.1 - 2e-45 152.5 5.4 1e-16 60.5 0.1 5.2 5 1 0 5 5 5 4 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM10173.1 - 3.9e-40 135.8 6.5 2.1e-10 40.5 0.0 5.1 5 0 0 5 5 5 5 Immunoglobulin domain Ig_3 PF13927.1 KFM10173.1 - 1.1e-31 109.1 15.3 1.1e-09 38.6 0.1 5.4 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.20 KFM10173.1 - 1.1e-17 63.9 14.7 1.3e-06 28.4 0.0 5.4 5 2 0 5 5 5 3 Immunoglobulin domain V-set PF07686.12 KFM10173.1 - 1.2e-16 60.6 12.0 9.4e-07 28.7 0.2 8.0 4 3 1 5 5 5 3 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM10173.1 - 2.7e-16 59.2 7.9 7.5e-06 25.7 0.0 5.6 5 1 0 5 5 5 4 CD80-like C2-set immunoglobulin domain C2-set PF05790.10 KFM10173.1 - 2.6e-12 46.5 6.5 1e-11 44.6 0.1 3.4 4 0 0 4 4 3 1 Immunoglobulin C2-set domain ICAM_N PF03921.9 KFM10173.1 - 1.6e-06 27.5 4.4 0.016 14.7 0.1 4.0 4 0 0 4 4 4 2 Intercellular adhesion molecule (ICAM), N-terminal domain Receptor_2B4 PF11465.3 KFM10173.1 - 5.6e-05 23.0 0.3 0.69 9.8 0.0 3.9 3 1 0 3 3 3 1 Natural killer cell receptor 2B4 Syndecan PF01034.15 KFM10173.1 - 0.0034 16.9 0.1 0.4 10.3 0.1 2.6 2 0 0 2 2 2 1 Syndecan domain C1-set PF07654.10 KFM10173.1 - 0.0059 16.5 2.1 0.23 11.4 0.0 3.8 3 0 0 3 3 3 1 Immunoglobulin C1-set domain ChlI PF13541.1 KFM10173.1 - 0.022 14.2 0.1 2.4 7.7 0.0 3.1 3 0 0 3 3 3 0 Subunit ChlI of Mg-chelatase RTC PF01137.16 KFM10174.1 - 2.6e-81 271.7 0.4 3e-81 271.5 0.3 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 KFM10174.1 - 4.2e-25 87.7 0.1 6.8e-25 87.0 0.1 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Integrin_alpha2 PF08441.7 KFM10175.1 - 5.9e-114 381.4 0.0 7.2e-114 381.1 0.0 1.1 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.18 KFM10175.1 - 6e-24 83.0 22.6 1.6e-07 30.7 0.5 4.5 4 0 0 4 4 4 4 FG-GAP repeat VCBS PF13517.1 KFM10175.1 - 5.6e-14 52.2 10.3 1.6e-05 25.1 1.4 4.4 2 1 2 4 4 4 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha PF00357.15 KFM10175.1 - 4.4e-05 22.9 0.9 9.2e-05 21.9 0.6 1.6 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region DUF1049 PF06305.6 KFM10175.1 - 0.024 14.1 0.2 0.045 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) TcdB_toxin_midN PF12256.3 KFM10175.1 - 0.027 13.8 1.2 1.4 8.2 0.0 2.9 2 1 1 3 3 3 0 Insecticide toxin TcdB middle/N-terminal region CD34_antigen PF06365.7 KFM10175.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF1191 PF06697.7 KFM10175.1 - 0.16 10.7 0.0 0.29 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) zf-CCCH PF00642.19 KFM10176.1 - 7.7e-06 25.4 0.8 7.7e-06 25.4 0.6 1.8 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KFM10176.1 - 0.0052 16.7 10.9 0.11 12.5 3.3 2.9 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type RVT_1 PF00078.22 KFM10177.1 - 6e-05 22.5 0.0 9.4e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) COPIIcoated_ERV PF07970.7 KFM10178.1 - 1.1e-56 191.9 1.5 1.5e-56 191.5 1.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KFM10178.1 - 4.1e-17 61.9 0.0 7e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Glyco_transf_29 PF00777.13 KFM10179.1 - 6.6e-78 261.5 0.0 7.4e-78 261.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) C2 PF00168.25 KFM10181.1 - 1.9e-19 69.2 0.0 3.1e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 C2 domain C2 PF00168.25 KFM10182.1 - 6.7e-38 128.4 0.0 5.9e-12 45.2 0.0 4.4 4 0 0 4 4 4 4 C2 domain FerB PF08150.7 KFM10182.1 - 2.8e-28 97.8 0.1 1.2e-27 95.7 0.0 2.1 2 0 0 2 2 2 1 FerB (NUC096) domain FerI PF08151.7 KFM10182.1 - 3.7e-23 81.3 0.0 7.7e-23 80.3 0.0 1.6 1 0 0 1 1 1 1 FerI (NUC094) domain Copine PF07002.11 KFM10183.1 - 2.4e-61 205.7 0.0 6.1e-61 204.4 0.0 1.6 2 0 0 2 2 2 1 Copine C2 PF00168.25 KFM10183.1 - 2.5e-22 78.5 0.0 6e-12 45.2 0.0 2.5 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.4 KFM10183.1 - 1.4e-10 41.3 0.0 2.4e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.23 KFM10183.1 - 0.0064 16.2 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain RRM_6 PF14259.1 KFM10184.1 - 1.3e-48 162.8 2.3 7e-12 45.1 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFM10184.1 - 4.3e-32 109.5 1.7 6.8e-09 35.2 0.0 5.3 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM10184.1 - 6.5e-14 51.5 0.1 0.013 15.2 0.0 5.3 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aminotran_5 PF00266.14 KFM10185.1 - 1.3e-93 313.7 0.0 1.5e-93 313.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KFM10185.1 - 2.1e-12 46.8 0.1 3e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KFM10185.1 - 6.4e-05 22.1 0.1 0.00011 21.4 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 KFM10185.1 - 0.003 16.0 0.0 0.005 15.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.15 KFM10185.1 - 0.012 13.8 0.0 0.019 13.2 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Romo1 PF10247.4 KFM10186.1 - 1.7e-27 95.3 18.9 2e-27 95.1 13.1 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.14 KFM10186.1 - 0.034 14.1 9.7 0.041 13.9 6.7 1.1 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family RRM_1 PF00076.17 KFM10187.1 - 1.7e-42 142.9 0.0 1.1e-24 85.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM10187.1 - 1.9e-31 107.8 0.2 4.3e-16 58.6 0.0 3.7 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM10187.1 - 5e-26 90.3 0.0 2.1e-11 43.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 KFM10187.1 - 1.6e-23 82.7 1.8 2.5e-22 78.9 1.2 2.5 1 1 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein MIP-T3 PF10243.4 KFM10187.1 - 0.079 11.4 21.1 0.13 10.7 14.6 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RhoGAP PF00620.22 KFM10188.1 - 1.2e-29 102.8 0.0 5.6e-29 100.7 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain MyTH4 PF00784.12 KFM10188.1 - 1.2e-17 63.8 3.7 8.2e-17 61.1 0.1 3.2 2 1 1 3 3 3 1 MyTH4 domain WW PF00397.21 KFM10188.1 - 3e-06 26.9 3.6 8.8e-06 25.4 2.5 1.8 1 0 0 1 1 1 1 WW domain PHD PF00628.24 KFM10189.1 - 1.1e-06 28.2 12.6 4.8e-06 26.1 8.8 2.3 1 0 0 1 1 1 1 PHD-finger DUF4537 PF15057.1 KFM10189.1 - 4.8e-05 23.1 0.0 0.00019 21.2 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Tudor-knot PF11717.3 KFM10189.1 - 0.0013 18.3 2.2 0.0058 16.3 0.9 2.6 3 0 0 3 3 3 1 RNA binding activity-knot of a chromodomain Rad9_Rad53_bind PF08605.5 KFM10189.1 - 0.0014 18.3 0.2 0.13 12.0 0.1 2.9 2 0 0 2 2 2 1 Fungal Rad9-like Rad53-binding zf-C2H2 PF00096.21 KFM10189.1 - 0.3 11.5 10.2 0.052 13.9 3.6 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type SH2 PF00017.19 KFM10190.1 - 4.8e-23 80.7 0.1 6.6e-23 80.3 0.1 1.2 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.1 KFM10190.1 - 2.3e-05 23.8 0.0 0.0002 20.8 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KFM10190.1 - 0.0019 17.6 0.0 0.0037 16.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM10190.1 - 0.0083 15.4 0.0 0.017 14.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain Ndr PF03096.9 KFM10191.1 - 4.1e-125 415.9 0.0 4.8e-125 415.7 0.0 1.0 1 0 0 1 1 1 1 Ndr family Abhydrolase_6 PF12697.2 KFM10191.1 - 2.3e-15 57.1 0.0 3.3e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFM10191.1 - 2.2e-05 24.1 0.0 8e-05 22.3 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Rap_GAP PF02145.10 KFM10192.1 - 0.00095 18.5 0.0 1.6 8.0 0.0 2.9 3 0 0 3 3 3 2 Rap/ran-GAP SNF2_N PF00176.18 KFM10193.1 - 1.2e-68 231.1 2.0 1.8e-68 230.5 1.4 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 KFM10193.1 - 3.3e-25 87.5 3.6 4.3e-13 48.7 0.7 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 KFM10193.1 - 7.8e-13 48.0 0.0 2.3e-12 46.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain BRK PF07533.11 KFM10193.1 - 1.2e-09 37.4 0.2 1.2e-08 34.2 0.0 2.3 2 0 0 2 2 2 1 BRK domain ResIII PF04851.10 KFM10193.1 - 1.4e-06 28.3 0.1 6.4e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KFM10193.1 - 3.8e-05 23.2 0.0 7.5e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase CHDCT2 PF08074.6 KFM10193.1 - 0.01 15.6 1.5 17 5.0 0.0 3.5 3 0 0 3 3 3 0 CHDCT2 (NUC038) domain RB_A PF01858.12 KFM10194.1 - 6.2e-80 267.4 0.3 6.2e-80 267.4 0.2 1.9 2 0 0 2 2 2 1 Retinoblastoma-associated protein A domain RB_B PF01857.15 KFM10194.1 - 1.4e-57 193.0 0.1 3.6e-57 191.6 0.1 1.8 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain DUF3452 PF11934.3 KFM10194.1 - 4.1e-45 152.5 0.2 1.1e-44 151.1 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3452) Rb_C PF08934.5 KFM10194.1 - 1.5e-07 31.1 1.5 3.5e-07 29.9 0.5 2.0 2 0 0 2 2 2 1 Rb C-terminal domain HD PF01966.17 KFM10195.1 - 1.3e-16 60.6 0.1 4.4e-16 58.9 0.0 2.0 2 0 0 2 2 2 1 HD domain HARE-HTH PF05066.8 KFM10195.1 - 0.016 15.5 0.1 0.047 14.0 0.0 1.8 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain TLD PF07534.11 KFM10196.1 - 9.7e-37 126.0 0.0 1.1e-36 125.8 0.0 1.0 1 0 0 1 1 1 1 TLD PIG-U PF06728.8 KFM10197.1 - 6e-106 354.5 49.5 6.9e-106 354.3 34.3 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U DOR PF14839.1 KFM10198.1 - 8.4e-31 107.3 9.0 6e-29 101.3 6.2 2.0 1 1 0 1 1 1 1 DOR family G_glu_transpept PF01019.16 KFM10199.1 - 1.4e-124 416.4 0.0 1.6e-124 416.1 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase PROL5-SMR PF15621.1 KFM10199.1 - 0.054 13.9 0.8 3.5 8.0 0.1 2.7 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family Rab5ip PF07019.7 KFM10200.1 - 7.5e-28 96.4 9.1 8.5e-28 96.3 6.3 1.0 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF441 PF04284.8 KFM10200.1 - 0.084 12.7 1.9 0.13 12.0 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF441) Clc-like PF07062.7 KFM10200.1 - 0.089 12.0 3.5 0.11 11.7 2.4 1.0 1 0 0 1 1 1 0 Clc-like DUF2244 PF10003.4 KFM10200.1 - 0.23 10.8 4.5 0.17 11.2 0.5 1.9 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Yip1 PF04893.12 KFM10200.1 - 0.56 9.6 9.8 3.5 7.0 6.8 1.9 1 1 0 1 1 1 0 Yip1 domain EF-hand_1 PF00036.27 KFM10201.1 - 4.3e-15 53.7 10.1 5.2e-08 31.6 1.1 4.5 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.1 KFM10201.1 - 1.4e-12 47.5 6.7 5.6e-08 32.8 1.0 2.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KFM10201.1 - 6.3e-12 44.3 7.6 6.6e-08 31.8 0.6 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 KFM10201.1 - 8.4e-10 38.1 9.5 1.6e-05 24.4 0.1 3.8 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 KFM10201.1 - 1.4e-05 24.1 1.3 1.4e-05 24.1 0.9 2.3 2 0 0 2 2 2 1 EF hand UPF0154 PF03672.8 KFM10201.1 - 0.00015 21.3 0.0 0.075 12.6 0.0 2.5 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 KFM10201.1 - 0.0046 16.9 0.7 2.2 8.3 0.1 2.3 2 0 0 2 2 2 2 Ca2+ insensitive EF hand EF-hand_9 PF14658.1 KFM10201.1 - 0.0056 16.5 0.0 3.5 7.6 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 KFM10201.1 - 0.072 13.1 0.7 0.23 11.5 0.2 1.8 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF1880 PF08976.6 KFM10201.1 - 0.13 12.4 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1880) Homeobox_KN PF05920.6 KFM10202.1 - 0.0018 17.9 2.7 0.0029 17.2 1.9 1.3 1 0 0 1 1 1 1 Homeobox KN domain GKAP PF03359.8 KFM10203.1 - 1.1e-116 390.4 14.7 1.1e-116 390.4 10.2 3.6 3 1 0 4 4 4 1 Guanylate-kinase-associated protein (GKAP) protein AAR2 PF05282.6 KFM10204.1 - 5.4e-67 226.2 0.0 6.6e-67 225.9 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein Alginate_lyase PF05426.7 KFM10204.1 - 0.019 14.2 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Alginate lyase 4_1_CTD PF05902.8 KFM10205.1 - 1.2e-43 147.7 3.3 1.2e-43 147.7 2.3 3.3 3 1 1 4 4 4 1 4.1 protein C-terminal domain (CTD) FERM_C PF09380.5 KFM10205.1 - 1.9e-23 82.4 0.0 3.5e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.5 KFM10205.1 - 3e-23 81.6 0.1 1.9e-22 79.0 0.0 2.2 2 0 0 2 2 2 1 FERM N-terminal domain FERM_M PF00373.13 KFM10205.1 - 7.9e-21 74.5 0.5 2.2e-20 73.1 0.0 2.0 2 0 0 2 2 2 1 FERM central domain SAB PF04382.8 KFM10205.1 - 1.2e-18 66.5 1.6 1.2e-18 66.5 1.1 2.2 2 0 0 2 2 2 1 SAB domain FA PF08736.6 KFM10205.1 - 1.2e-18 66.6 4.3 3e-18 65.3 3.0 1.8 1 0 0 1 1 1 1 FERM adjacent (FA) RRM_1 PF00076.17 KFM10206.1 - 4e-21 74.4 0.0 6.5e-14 51.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM10206.1 - 6.4e-13 48.4 0.0 5.6e-10 39.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM10206.1 - 4e-09 36.1 0.0 0.0022 17.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFM10206.1 - 3.1e-05 23.7 0.1 0.00012 21.9 0.0 2.0 2 0 0 2 2 2 1 RNA binding motif MBT PF02820.13 KFM10207.1 - 2.3e-96 315.7 2.9 3.7e-32 110.0 0.0 3.4 3 0 0 3 3 3 3 mbt repeat zf-C2HC PF01530.13 KFM10207.1 - 5.8e-17 61.1 19.8 3.2e-14 52.3 6.3 2.7 1 1 1 2 2 2 2 Zinc finger, C2HC type SAM_1 PF00536.25 KFM10207.1 - 1.4e-12 47.5 0.0 2.6e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ste50p-SAM PF09235.5 KFM10207.1 - 0.031 14.2 0.1 0.057 13.4 0.1 1.4 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Ig_2 PF13895.1 KFM10208.1 - 2.1e-15 56.5 0.3 2.1e-06 27.7 0.0 2.0 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 KFM10208.1 - 6.3e-09 36.2 0.6 0.0026 18.2 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 KFM10208.1 - 3.2e-08 33.5 3.6 0.00013 22.0 0.6 2.3 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 KFM10208.1 - 1.9e-05 24.4 0.1 0.021 14.6 0.0 3.0 3 0 0 3 3 3 2 Immunoglobulin I-set domain V-set PF07686.12 KFM10208.1 - 9.2e-05 22.3 1.8 0.0043 16.9 0.2 3.2 3 1 0 3 3 3 1 Immunoglobulin V-set domain Hist_deacetyl PF00850.14 KFM10209.1 - 1.1e-60 205.5 0.0 1.4e-60 205.2 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain Phage_head_chap PF11113.3 KFM10209.1 - 0.18 11.7 0.6 0.52 10.2 0.4 1.8 1 1 0 1 1 1 0 Head assembly gene product Big_2 PF02368.13 KFM10210.1 - 2.6e-11 43.2 19.0 6.8e-07 29.0 0.0 7.8 8 0 0 8 8 8 2 Bacterial Ig-like domain (group 2) DUF3313 PF11769.3 KFM10210.1 - 0.0036 16.6 2.6 1.4 8.2 0.3 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF3313) PQQ PF01011.16 KFM10210.1 - 0.099 12.2 0.1 0.27 10.8 0.0 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat bZIP_2 PF07716.10 KFM10211.1 - 0.00043 20.0 3.0 0.00061 19.5 2.1 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KFM10211.1 - 0.0095 15.8 1.9 0.011 15.7 1.3 1.2 1 0 0 1 1 1 1 bZIP transcription factor TSC22 PF01166.13 KFM10211.1 - 0.013 15.4 0.7 0.014 15.3 0.5 1.2 1 0 0 1 1 1 0 TSC-22/dip/bun family DivIC PF04977.10 KFM10211.1 - 0.015 14.8 2.1 0.016 14.6 1.5 1.2 1 0 0 1 1 1 0 Septum formation initiator BMFP PF04380.8 KFM10211.1 - 0.029 14.5 2.4 0.038 14.1 1.7 1.2 1 0 0 1 1 1 0 Membrane fusogenic activity Phage_GP20 PF06810.6 KFM10211.1 - 0.033 13.6 0.4 0.033 13.6 0.3 1.0 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF4439 PF14530.1 KFM10211.1 - 0.064 13.7 0.0 0.064 13.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4439) DUF2205 PF10224.4 KFM10211.1 - 0.079 12.5 0.6 0.079 12.5 0.4 1.2 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) HSBP1 PF06825.7 KFM10211.1 - 0.084 12.4 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Heat shock factor binding protein 1 DUF1875 PF08961.5 KFM10211.1 - 0.088 12.1 1.2 0.087 12.1 0.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1875) DUF2680 PF10925.3 KFM10211.1 - 0.091 12.6 0.6 0.13 12.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) ORF6C PF10552.4 KFM10211.1 - 0.098 12.3 1.0 0.1 12.3 0.7 1.0 1 0 0 1 1 1 0 ORF6C domain Pox_A_type_inc PF04508.7 KFM10211.1 - 0.11 12.3 1.7 0.5 10.2 0.7 2.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat CASP_C PF08172.7 KFM10211.1 - 0.17 10.8 1.0 0.17 10.8 0.7 1.1 1 0 0 1 1 1 0 CASP C terminal K-box PF01486.12 KFM10211.1 - 0.27 11.0 2.9 0.3 10.8 2.0 1.2 1 0 0 1 1 1 0 K-box region CENP-Q PF13094.1 KFM10211.1 - 0.3 11.1 4.9 0.31 11.0 3.4 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Rab5-bind PF09311.6 KFM10211.1 - 0.34 10.7 5.5 0.42 10.4 3.8 1.2 1 0 0 1 1 1 0 Rabaptin-like protein ATG16 PF08614.6 KFM10211.1 - 0.35 10.6 3.3 0.35 10.6 2.3 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) IncA PF04156.9 KFM10211.1 - 0.56 9.7 5.4 0.62 9.6 3.8 1.0 1 0 0 1 1 1 0 IncA protein Sec7 PF01369.15 KFM10212.1 - 6.7e-62 208.5 0.1 2e-61 207.0 0.0 1.8 2 0 0 2 2 2 1 Sec7 domain IQ PF00612.22 KFM10212.1 - 0.18 11.5 1.1 0.62 9.8 0.2 2.3 2 0 0 2 2 2 0 IQ calmodulin-binding motif RNA_pol_Rpb2_6 PF00562.23 KFM10213.1 - 5.9e-127 423.5 0.3 1.1e-126 422.7 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KFM10213.1 - 7.4e-67 224.2 0.0 1.2e-66 223.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KFM10213.1 - 2e-56 190.4 0.0 6.5e-56 188.7 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 KFM10213.1 - 8.3e-29 99.1 0.9 1.7e-28 98.1 0.6 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 KFM10213.1 - 4.4e-22 77.6 0.0 9.5e-22 76.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 KFM10213.1 - 3.4e-20 71.7 0.7 6.7e-20 70.7 0.5 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Amidoligase_2 PF12224.3 KFM10213.1 - 0.049 13.2 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative amidoligase enzyme zf-H2C2_2 PF13465.1 KFM10214.1 - 6.4e-30 101.9 67.3 7.3e-09 35.4 0.8 11.4 11 1 0 11 11 11 7 Zinc-finger double domain zf-H2C2_5 PF13909.1 KFM10214.1 - 1.5e-20 72.1 73.5 8.8e-05 22.5 1.3 9.5 9 0 0 9 9 9 7 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 KFM10214.1 - 3.4e-15 55.3 78.1 0.00099 19.3 2.8 9.5 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM10214.1 - 2.2e-10 40.1 74.1 0.015 15.6 1.8 9.4 9 0 0 9 9 9 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM10214.1 - 0.0071 16.4 0.8 0.0071 16.4 0.6 7.5 8 0 0 8 8 8 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFM10214.1 - 1.2 9.3 43.4 0.64 10.1 5.4 6.2 2 1 3 6 6 6 0 C2H2 type zinc-finger (2 copies) GAGA PF09237.6 KFM10214.1 - 6.3 6.4 14.0 6.7 6.3 0.1 5.7 4 1 1 6 6 6 0 GAGA factor DUF1183 PF06682.7 KFM10215.1 - 7.7e-96 321.4 2.3 8.7e-96 321.2 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) Vps55 PF04133.9 KFM10216.1 - 8.9e-41 138.4 5.1 1e-40 138.2 3.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 YwiC PF14256.1 KFM10216.1 - 0.0078 16.2 5.2 0.012 15.7 3.6 1.3 1 1 0 1 1 1 1 YwiC-like protein ABC2_membrane PF01061.19 KFM10216.1 - 5.6 6.0 13.5 2.7 7.1 3.1 2.1 2 0 0 2 2 2 0 ABC-2 type transporter SRP72 PF08492.7 KFM10217.1 - 2.9e-20 72.4 7.0 2.9e-20 72.4 4.8 3.1 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_14 PF13428.1 KFM10217.1 - 6.6e-15 54.2 6.6 0.18 12.5 0.0 8.1 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFM10217.1 - 7.6e-15 55.0 19.2 0.0038 17.5 0.1 7.2 6 2 2 8 8 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 KFM10217.1 - 1.6e-14 52.5 16.8 0.0045 16.7 0.0 7.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFM10217.1 - 1.6e-10 41.3 6.8 0.33 11.6 0.0 7.0 6 2 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFM10217.1 - 3.5e-10 39.0 10.4 0.022 14.3 0.0 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFM10217.1 - 4.8e-10 39.2 18.3 8.9e-07 28.7 0.6 6.4 5 3 2 7 7 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFM10217.1 - 3.3e-09 36.2 22.2 0.00059 19.4 0.6 7.7 6 2 4 10 10 9 3 TPR repeat Apc3 PF12895.2 KFM10217.1 - 3.4e-09 36.7 17.5 3.2e-05 23.9 1.5 6.2 3 3 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KFM10217.1 - 1.2e-06 28.5 21.3 0.25 11.8 0.1 8.7 9 0 0 9 9 9 2 Tetratricopeptide repeat BTAD PF03704.12 KFM10217.1 - 7.3e-06 26.3 6.3 0.19 11.9 0.1 4.7 4 1 0 4 4 4 2 Bacterial transcriptional activator domain TPR_8 PF13181.1 KFM10217.1 - 8.2e-05 22.1 12.8 0.46 10.3 0.0 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFM10217.1 - 0.00053 19.7 5.7 0.87 9.4 0.0 5.3 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFM10217.1 - 0.00068 19.2 8.8 11 6.1 0.0 6.2 7 0 0 7 7 6 0 Tetratricopeptide repeat PPR PF01535.15 KFM10217.1 - 0.0014 18.4 0.1 28 4.9 0.0 5.3 5 0 0 5 5 5 0 PPR repeat TPR_17 PF13431.1 KFM10217.1 - 0.0083 16.2 1.8 21 5.6 0.0 5.3 5 0 0 5 5 4 0 Tetratricopeptide repeat PPR_2 PF13041.1 KFM10217.1 - 0.048 13.6 0.1 33 4.5 0.0 4.3 5 0 0 5 5 5 0 PPR repeat family Dishevelled PF02377.10 KFM10217.1 - 0.051 13.7 0.1 0.21 11.8 0.1 2.0 1 0 0 1 1 1 0 Dishevelled specific domain CorA PF01544.13 KFM10217.1 - 0.095 11.7 4.6 0.025 13.6 0.5 1.9 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Arf PF00025.16 KFM10218.1 - 5.4e-38 129.9 0.0 6.1e-38 129.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KFM10218.1 - 2e-12 46.7 0.0 2.4e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KFM10218.1 - 3.9e-10 40.2 0.0 6.1e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 KFM10218.1 - 2.1e-09 36.9 0.0 2.4e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KFM10218.1 - 6.6e-07 28.7 0.0 8.6e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KFM10218.1 - 0.00019 20.2 0.1 0.0033 16.1 0.0 2.2 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.18 KFM10218.1 - 0.00057 19.8 0.0 0.00091 19.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KFM10218.1 - 0.0012 18.8 0.2 0.0028 17.6 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFM10218.1 - 0.0065 16.6 0.3 0.05 13.7 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KFM10218.1 - 0.017 15.2 0.1 0.071 13.3 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.12 KFM10218.1 - 0.042 13.3 0.2 3.1 7.2 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SRP54 PF00448.17 KFM10218.1 - 0.056 12.8 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.22 KFM10218.1 - 0.11 12.8 0.1 0.24 11.6 0.1 1.8 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.7 KFM10218.1 - 0.11 12.1 0.5 0.89 9.1 0.3 2.1 1 1 0 1 1 1 0 NACHT domain DUF2332 PF10094.4 KFM10218.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2332) Dynamin_N PF00350.18 KFM10218.1 - 0.12 12.1 0.2 0.71 9.6 0.0 2.0 1 1 1 2 2 2 0 Dynamin family Homeobox PF00046.24 KFM10219.1 - 4.3e-10 39.0 0.1 5.1e-10 38.8 0.1 1.1 1 0 0 1 1 1 1 Homeobox domain Colicin_Pyocin PF01320.13 KFM10219.1 - 0.0047 16.7 0.0 0.0057 16.4 0.0 1.1 1 0 0 1 1 1 1 Colicin immunity protein / pyocin immunity protein Homez PF11569.3 KFM10219.1 - 0.053 12.5 0.0 0.074 12.1 0.0 1.3 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Kazal_1 PF00050.16 KFM10220.1 - 4.7e-13 48.9 6.2 5e-13 48.8 4.3 1.0 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 KFM10220.1 - 2.2e-10 40.3 4.6 2.6e-10 40.0 3.2 1.2 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain DSPc PF00782.15 KFM10221.1 - 7.5e-45 151.7 0.2 9.5e-45 151.4 0.1 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFM10221.1 - 1.2e-07 31.3 0.0 1.6e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KFM10221.1 - 0.016 15.2 0.0 0.023 14.7 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate CDKN3 PF05706.7 KFM10221.1 - 0.045 13.2 0.2 0.069 12.6 0.1 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) DUF3678 PF12435.3 KFM10221.1 - 0.47 10.0 6.3 0.093 12.3 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) Ank_2 PF12796.2 KFM10222.1 - 1.7e-159 518.6 72.7 4.5e-20 71.7 0.2 10.5 3 3 8 12 12 12 12 Ankyrin repeats (3 copies) Ank PF00023.25 KFM10222.1 - 3e-143 459.1 51.3 7.3e-12 44.4 0.1 19.3 19 1 0 19 19 19 15 Ankyrin repeat Ank_5 PF13857.1 KFM10222.1 - 1.1e-115 375.0 53.3 1.7e-12 47.1 0.1 16.1 5 5 11 16 16 16 15 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFM10222.1 - 6e-114 370.6 32.2 1.7e-14 53.8 0.2 15.8 8 5 9 17 17 17 16 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM10222.1 - 1.4e-100 318.9 37.4 6.4e-08 32.0 0.1 19.3 20 0 0 20 20 20 15 Ankyrin repeat PARP PF00644.15 KFM10222.1 - 8.4e-28 97.2 3.4 1.8e-25 89.5 2.4 2.4 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain SAM_2 PF07647.12 KFM10222.1 - 6.4e-15 54.7 0.2 1.4e-14 53.6 0.2 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFM10222.1 - 3.7e-12 46.2 0.5 8.7e-12 45.0 0.4 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Shigella_OspC PF06128.6 KFM10222.1 - 0.00025 20.6 0.8 15 4.9 0.0 5.1 6 0 0 6 6 6 0 Shigella flexneri OspC protein Vps39_1 PF10366.4 KFM10222.1 - 0.004 17.1 1.4 5.6 7.0 0.0 3.9 4 1 0 4 4 4 2 Vacuolar sorting protein 39 domain 1 LRR_4 PF12799.2 KFM10223.1 - 5.7e-38 127.9 14.5 1.1e-08 34.5 1.5 6.7 5 1 0 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM10223.1 - 6.2e-31 105.9 21.5 3.5e-08 33.0 1.4 6.0 4 1 2 6 6 6 5 Leucine rich repeat LRR_1 PF00560.28 KFM10223.1 - 7.3e-24 80.1 19.8 0.028 14.4 0.5 10.9 10 0 0 10 10 10 9 Leucine Rich Repeat LRR_7 PF13504.1 KFM10223.1 - 1.2e-13 48.8 22.6 0.7 10.3 0.2 10.8 10 0 0 10 10 10 5 Leucine rich repeat LRR_6 PF13516.1 KFM10223.1 - 1.6e-07 30.6 15.7 1.7 8.9 0.1 8.8 9 1 0 9 9 9 3 Leucine Rich repeat LRR_9 PF14580.1 KFM10223.1 - 5.2e-05 22.8 4.1 0.43 10.1 0.1 3.7 1 1 3 4 4 4 2 Leucine-rich repeat RNase_T PF00929.19 KFM10224.1 - 3.4e-26 92.4 0.0 1e-25 90.9 0.0 1.7 2 0 0 2 2 2 1 Exonuclease SAP PF02037.22 KFM10224.1 - 4.3e-08 32.4 0.5 8.4e-08 31.5 0.4 1.5 1 0 0 1 1 1 1 SAP domain CBM_21 PF03370.8 KFM10225.1 - 1e-33 115.6 0.4 1.7e-33 114.9 0.1 1.5 2 0 0 2 2 2 1 Putative phosphatase regulatory subunit CBM_25 PF03423.8 KFM10225.1 - 0.044 13.8 0.1 0.093 12.8 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) Ldl_recept_b PF00058.12 KFM10226.1 - 1.7e-18 66.6 9.0 6.5e-09 35.9 0.0 5.8 5 2 0 5 5 5 3 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.1 KFM10226.1 - 2.7e-13 49.7 21.7 1.3e-07 31.5 5.3 3.0 2 1 0 2 2 2 2 Coagulation Factor Xa inhibitory site Ldl_recept_a PF00057.13 KFM10226.1 - 1e-12 47.7 28.1 6.3e-11 41.9 4.3 3.0 3 0 0 3 3 3 2 Low-density lipoprotein receptor domain class A cEGF PF12662.2 KFM10226.1 - 3.2e-06 26.6 5.6 0.00022 20.7 0.3 3.3 3 0 0 3 3 3 2 Complement Clr-like EGF-like EGF_CA PF07645.10 KFM10226.1 - 3.2e-05 23.8 3.9 3.2e-05 23.8 2.7 3.7 3 1 0 3 3 3 1 Calcium-binding EGF domain GBP_PSP PF02425.10 KFM10226.1 - 0.24 10.9 2.9 0.23 11.0 0.4 2.2 2 0 0 2 2 2 0 Paralytic/GBP/PSP peptide PMP22_Claudin PF00822.15 KFM10227.1 - 2.3e-15 56.6 0.4 2.9e-15 56.3 0.2 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFM10227.1 - 4e-05 23.3 3.1 4e-05 23.3 2.1 1.6 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction L_HGMIC_fpl PF10242.4 KFM10227.1 - 0.0028 17.6 1.3 0.0042 17.1 0.9 1.3 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Clc-like PF07062.7 KFM10227.1 - 0.0051 16.0 1.1 0.0071 15.6 0.1 1.7 2 0 0 2 2 2 1 Clc-like DUF4131 PF13567.1 KFM10227.1 - 0.86 8.9 8.2 0.5 9.7 3.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DUF872 PF05915.7 KFM10227.1 - 1.7 8.5 3.7 0.92 9.3 0.1 2.2 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF872) DUF2892 PF11127.3 KFM10227.1 - 2.4 8.0 12.6 0.077 12.8 1.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2892) DUF3040 PF11239.3 KFM10227.1 - 3.9 7.6 7.9 0.52 10.3 0.6 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) MBOAT PF03062.14 KFM10229.1 - 1.1e-14 54.3 14.3 1.3e-10 40.9 7.9 2.3 2 1 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family Ribosomal_S3Ae PF01015.13 KFM10230.1 - 8.5e-82 273.2 5.9 9.8e-82 273.0 4.1 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.11 KFM10230.1 - 0.0037 16.6 0.2 0.019 14.2 0.0 2.2 1 1 1 2 2 2 1 Partial alpha/beta-hydrolase lipase region SH3_1 PF00018.23 KFM10231.1 - 2.3e-58 193.3 3.4 3.9e-16 58.1 0.1 4.5 4 0 0 4 4 4 4 SH3 domain SH3_9 PF14604.1 KFM10231.1 - 9.6e-55 181.9 0.7 4.1e-14 51.8 0.0 5.4 5 0 0 5 5 5 5 Variant SH3 domain SH3_2 PF07653.12 KFM10231.1 - 2.3e-42 142.2 1.2 1.7e-08 33.8 0.0 5.4 5 0 0 5 5 5 5 Variant SH3 domain TUDOR PF00567.19 KFM10231.1 - 0.0016 18.2 0.0 0.41 10.4 0.0 2.4 2 0 0 2 2 2 2 Tudor domain p47_phox_C PF08944.6 KFM10232.1 - 1.3 9.3 11.3 0.18 12.0 1.9 2.8 3 0 0 3 3 3 0 NADPH oxidase subunit p47Phox, C terminal domain GatB_N PF02934.10 KFM10233.1 - 7e-104 346.7 0.0 9.6e-104 346.2 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 KFM10233.1 - 8.9e-40 135.8 7.8 1.5e-39 135.0 5.4 1.4 1 0 0 1 1 1 1 GatB domain EMP24_GP25L PF01105.19 KFM10233.1 - 0.064 12.9 0.1 0.16 11.7 0.0 1.6 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD WD40 PF00400.27 KFM10234.1 - 1.6e-59 195.7 31.3 8.8e-11 41.2 0.3 8.6 8 1 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 KFM10234.1 - 1.4e-17 63.0 17.4 0.0013 16.9 0.3 6.9 1 1 5 6 6 6 6 Nucleoporin Nup120/160 F-box-like PF12937.2 KFM10234.1 - 2.3e-13 49.6 1.6 4e-13 48.8 1.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFM10234.1 - 7e-09 35.1 0.3 1.2e-08 34.3 0.2 1.4 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 KFM10234.1 - 1.7e-06 27.6 5.2 1.7e-05 24.4 2.7 3.6 2 1 0 2 2 2 1 PQQ-like domain CDtoxinA PF03498.9 KFM10234.1 - 0.0011 18.3 2.3 0.13 11.6 0.2 3.4 2 1 1 3 3 3 1 Cytolethal distending toxin A/C family Nop14 PF04147.7 KFM10234.1 - 0.012 13.5 24.3 0.016 13.1 16.8 1.1 1 0 0 1 1 1 0 Nop14-like family CENP-T PF15511.1 KFM10234.1 - 1.8 7.7 19.8 2.6 7.1 13.7 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TMEM154 PF15102.1 KFM10235.1 - 1.4e-38 131.8 3.9 2e-38 131.3 2.7 1.2 1 0 0 1 1 1 1 TMEM154 protein family DUF912 PF06024.7 KFM10235.1 - 4.5e-07 29.8 0.1 7.1e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Rifin_STEVOR PF02009.11 KFM10235.1 - 5.8e-07 29.4 0.0 8.5e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Rifin/stevor family SIT PF15330.1 KFM10235.1 - 0.0032 17.5 0.6 0.0049 16.9 0.1 1.6 1 1 1 2 2 2 1 SHP2-interacting transmembrane adaptor protein, SIT DUF3609 PF12259.3 KFM10235.1 - 0.0036 16.0 0.1 0.0043 15.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3609) DUF4448 PF14610.1 KFM10235.1 - 0.0037 16.7 0.0 0.0055 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) CcmH PF03918.9 KFM10235.1 - 0.0049 15.8 0.0 0.007 15.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome C biogenesis protein CCSMST1 PF15013.1 KFM10235.1 - 0.006 16.4 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 CCSMST1 family EphA2_TM PF14575.1 KFM10235.1 - 0.007 16.7 0.2 0.015 15.6 0.0 1.6 2 0 0 2 2 1 1 Ephrin type-A receptor 2 transmembrane domain DUF4064 PF13273.1 KFM10235.1 - 0.0081 16.2 0.7 0.013 15.6 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) AMA-1 PF02430.10 KFM10235.1 - 0.0084 15.0 0.2 0.014 14.3 0.1 1.3 1 1 0 1 1 1 1 Apical membrane antigen 1 BatD PF13584.1 KFM10235.1 - 0.0086 14.7 0.0 0.0093 14.5 0.0 1.1 1 0 0 1 1 1 1 Oxygen tolerance DUF2207 PF09972.4 KFM10235.1 - 0.0087 14.6 0.0 0.01 14.4 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF843 PF05814.6 KFM10235.1 - 0.009 15.7 0.6 0.016 14.9 0.3 1.6 1 1 0 1 1 1 1 Baculovirus protein of unknown function (DUF843) DUF3377 PF11857.3 KFM10235.1 - 0.0096 15.5 1.2 0.016 14.8 0.6 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3377) Herpes_gE PF02480.11 KFM10235.1 - 0.014 13.6 0.0 0.014 13.6 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SID-1_RNA_chan PF13965.1 KFM10235.1 - 0.017 13.3 1.0 0.018 13.2 0.7 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CD34_antigen PF06365.7 KFM10235.1 - 0.019 14.5 0.1 0.023 14.3 0.1 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family YajC PF02699.10 KFM10235.1 - 0.028 14.1 0.1 0.028 14.1 0.1 1.6 2 0 0 2 2 1 0 Preprotein translocase subunit TAS2R PF05296.8 KFM10235.1 - 0.03 13.2 0.2 0.036 12.9 0.1 1.1 1 0 0 1 1 1 0 Mammalian taste receptor protein (TAS2R) LRRC37AB_C PF14914.1 KFM10235.1 - 0.036 13.4 0.6 0.051 13.0 0.4 1.2 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain DUF443 PF04276.7 KFM10235.1 - 0.043 13.2 1.6 0.053 12.9 0.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF443) Sec66 PF09802.4 KFM10235.1 - 0.046 13.1 0.0 0.064 12.6 0.0 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 Glycophorin_A PF01102.13 KFM10235.1 - 0.046 13.4 0.4 0.063 13.0 0.3 1.3 1 0 0 1 1 1 0 Glycophorin A 7TM_GPCR_Srv PF10323.4 KFM10235.1 - 0.05 12.7 0.0 0.063 12.4 0.0 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv gpUL132 PF11359.3 KFM10235.1 - 0.057 12.7 0.1 0.068 12.4 0.1 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 ODV-E18 PF10717.4 KFM10235.1 - 0.064 12.7 3.6 0.073 12.5 1.6 1.8 2 1 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 PspB PF06667.7 KFM10235.1 - 0.074 12.9 2.0 0.11 12.5 1.1 1.6 1 1 0 1 1 1 0 Phage shock protein B Cytomega_TRL10 PF06084.6 KFM10235.1 - 0.082 12.7 0.4 0.14 11.9 0.0 1.6 2 0 0 2 2 1 0 Cytomegalovirus TRL10 protein TMEM51 PF15345.1 KFM10235.1 - 0.097 12.3 0.1 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Peptidase_S49_N PF08496.5 KFM10235.1 - 0.14 11.9 0.6 0.2 11.4 0.3 1.4 1 1 0 1 1 1 0 Peptidase family S49 N-terminal DUF4446 PF14584.1 KFM10235.1 - 0.21 11.3 1.0 0.34 10.7 0.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) SKG6 PF08693.5 KFM10235.1 - 0.92 8.8 4.4 2 7.8 3.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2254 PF10011.4 KFM10235.1 - 1.2 7.5 3.6 13 4.1 2.2 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2254) DDE_1 PF03184.14 KFM10236.1 - 2.6e-48 164.0 0.1 5.7e-48 162.9 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 KFM10236.1 - 3.7e-19 68.3 0.0 6.6e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 KFM10236.1 - 5e-09 35.4 2.3 1.1e-08 34.3 1.6 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain DDE_3 PF13358.1 KFM10236.1 - 0.00021 21.0 0.0 0.00043 20.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.1 KFM10236.1 - 0.0025 17.3 0.0 0.036 13.7 0.0 2.8 2 0 0 2 2 2 1 Homeodomain-like domain CENP-B_dimeris PF09026.5 KFM10236.1 - 0.012 15.8 0.2 0.024 14.8 0.2 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain HTH_Tnp_1 PF01527.15 KFM10236.1 - 0.017 15.0 0.1 0.053 13.4 0.0 1.9 1 0 0 1 1 1 0 Transposase Arfaptin PF06456.8 KFM10237.1 - 3.1e-81 272.0 9.5 4.2e-81 271.6 6.6 1.1 1 0 0 1 1 1 1 Arfaptin-like domain BAR PF03114.13 KFM10237.1 - 0.01 15.3 12.2 0.034 13.6 8.5 1.9 1 1 0 1 1 1 1 BAR domain FH2 PF02181.18 KFM10238.1 - 6.6e-91 304.9 8.2 1e-90 304.3 5.7 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain NHL PF01436.16 KFM10239.1 - 1e-48 160.8 18.4 9.3e-10 37.9 0.1 6.5 6 0 0 6 6 6 6 NHL repeat Filamin PF00630.14 KFM10239.1 - 1.1e-18 67.6 0.0 5.3e-18 65.4 0.0 2.2 1 0 0 1 1 1 1 Filamin/ABP280 repeat SGL PF08450.7 KFM10239.1 - 5.3e-12 45.6 3.4 4.2e-05 23.0 0.0 5.6 1 1 4 6 6 6 3 SMP-30/Gluconolaconase/LRE-like region zf-B_box PF00643.19 KFM10239.1 - 1.5e-10 40.8 3.2 1.5e-10 40.8 2.2 3.1 3 1 0 3 3 3 1 B-box zinc finger zf-C3HC4_2 PF13923.1 KFM10239.1 - 2.4e-08 33.8 10.8 2.4e-08 33.8 7.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM10239.1 - 4.3e-08 32.6 10.2 4.3e-08 32.6 7.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM10239.1 - 1.2e-07 31.3 8.7 1.2e-07 31.3 6.1 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 KFM10239.1 - 1.3e-07 31.3 10.2 1.3e-07 31.3 7.1 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFM10239.1 - 2.1e-07 30.5 7.3 2.1e-07 30.5 5.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFM10239.1 - 1.3e-06 27.9 5.8 1.8e-06 27.5 2.4 2.6 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KFM10239.1 - 6.2e-05 22.7 11.2 6.2e-05 22.7 7.8 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 KFM10239.1 - 0.0055 16.5 1.4 0.014 15.1 1.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger SBBP PF06739.6 KFM10239.1 - 0.0065 16.2 1.7 0.42 10.4 0.2 3.4 4 0 0 4 4 4 1 Beta-propeller repeat Big_1 PF02369.11 KFM10239.1 - 0.022 14.6 0.4 0.1 12.5 0.3 2.2 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) Ldl_recept_b PF00058.12 KFM10239.1 - 0.027 14.7 0.0 21 5.5 0.0 4.0 4 0 0 4 4 4 0 Low-density lipoprotein receptor repeat class B IBR PF01485.16 KFM10239.1 - 0.79 9.6 13.5 0.053 13.3 0.8 3.0 2 1 1 3 3 3 0 IBR domain VCBS PF13517.1 KFM10239.1 - 2.6 8.4 7.9 36 4.8 0.0 4.5 2 1 3 5 5 5 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella zf-RING_6 PF14835.1 KFM10239.1 - 3.9 7.3 12.0 0.028 14.1 2.3 1.9 2 0 0 2 2 1 0 zf-RING of BARD1-type protein Mnd1 PF03962.10 KFM10240.1 - 6.2e-73 244.4 7.3 7e-73 244.3 5.0 1.0 1 0 0 1 1 1 1 Mnd1 family Penicillinase_R PF03965.11 KFM10240.1 - 2.9e-06 27.3 0.5 5.2e-06 26.5 0.4 1.4 1 0 0 1 1 1 1 Penicillinase repressor DivIC PF04977.10 KFM10240.1 - 8.1e-06 25.2 11.9 7.1e-05 22.2 1.6 2.9 1 1 2 3 3 3 2 Septum formation initiator TBPIP PF07106.8 KFM10240.1 - 0.00044 19.8 5.5 0.00064 19.3 3.8 1.2 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DsrD PF08679.6 KFM10240.1 - 0.0076 16.2 2.3 0.04 13.9 0.2 2.5 2 0 0 2 2 2 1 Dissimilatory sulfite reductase D (DsrD) TrmB PF01978.14 KFM10240.1 - 0.052 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB S10_plectin PF03501.10 KFM10240.1 - 0.065 13.0 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Plectin/S10 domain DUF342 PF03961.8 KFM10240.1 - 0.095 11.0 4.9 0.14 10.5 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4277 PF14104.1 KFM10240.1 - 0.11 12.7 0.1 2.2 8.5 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4277) Peptidase_M13 PF01431.16 KFM10240.1 - 0.14 11.3 0.3 0.19 10.8 0.2 1.2 1 0 0 1 1 1 0 Peptidase family M13 RasGAP_C PF03836.10 KFM10240.1 - 0.16 11.6 5.6 0.13 11.9 2.4 2.0 2 1 0 2 2 2 0 RasGAP C-terminus APG6 PF04111.7 KFM10240.1 - 0.18 10.8 7.6 0.24 10.3 5.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF904 PF06005.7 KFM10240.1 - 0.24 11.7 11.8 0.94 9.8 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF904) AAA_23 PF13476.1 KFM10240.1 - 0.48 10.7 8.7 0.82 9.9 6.1 1.4 1 0 0 1 1 1 0 AAA domain DUF4574 PF15141.1 KFM10240.1 - 2 8.1 4.5 5.1 6.9 0.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4574) Seryl_tRNA_N PF02403.17 KFM10240.1 - 2.7 8.0 11.9 4.9 7.2 8.0 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 KFM10240.1 - 5.1 6.6 11.1 7.7 6.0 7.7 1.2 1 0 0 1 1 1 0 IncA protein DUF4078 PF13300.1 KFM10240.1 - 5.7 7.1 8.4 19 5.4 1.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4078) DUF3651 PF12371.3 KFM10241.1 - 5.2e-09 35.9 2.6 1.7e-05 24.7 0.1 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF3651) LRR_8 PF13855.1 KFM10242.1 - 8.7e-41 137.5 38.5 2.6e-14 52.6 4.3 7.6 6 1 1 7 7 7 6 Leucine rich repeat TIR PF01582.15 KFM10242.1 - 4.7e-34 116.8 1.1 8.4e-34 116.0 0.8 1.4 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.2 KFM10242.1 - 2.3e-26 90.9 47.1 1.1e-06 28.1 0.4 9.3 4 2 7 11 11 11 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM10242.1 - 1.1e-16 58.2 36.5 0.0082 16.0 0.1 12.9 10 2 1 11 11 11 8 Leucine Rich Repeat TIR_2 PF13676.1 KFM10242.1 - 1.1e-12 47.9 0.0 2.5e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 TIR domain LRR_6 PF13516.1 KFM10242.1 - 7.5e-08 31.6 35.4 4.1 7.7 0.3 11.3 11 1 1 12 12 12 5 Leucine Rich repeat LRR_7 PF13504.1 KFM10242.1 - 4.1e-07 29.1 35.5 2.1 8.9 0.0 11.6 12 1 1 13 13 13 3 Leucine rich repeat LRR_5 PF13306.1 KFM10242.1 - 7.8e-06 25.6 0.6 5.9e-05 22.7 0.0 2.7 3 1 0 3 3 3 1 Leucine rich repeats (6 copies) LRR_9 PF14580.1 KFM10242.1 - 0.00087 18.8 7.6 0.2 11.2 0.2 4.2 2 2 1 4 4 4 1 Leucine-rich repeat DUF1863 PF08937.6 KFM10242.1 - 0.0057 16.6 0.1 0.037 14.0 0.1 2.2 1 1 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) zf-RING_2 PF13639.1 KFM10243.1 - 1.2e-10 40.9 6.2 1.2e-10 40.9 4.3 1.9 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 KFM10243.1 - 4.3e-09 36.3 3.9 9.4e-09 35.2 2.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KFM10243.1 - 1.7e-05 24.4 7.0 3.5e-05 23.4 4.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KFM10243.1 - 3.5e-05 23.3 5.0 8.7e-05 22.0 3.5 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM10243.1 - 0.00061 19.4 6.8 0.0045 16.6 5.1 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM10243.1 - 0.0011 18.9 8.5 0.0037 17.2 5.9 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFM10243.1 - 0.0065 16.2 4.9 0.041 13.7 3.4 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KFM10243.1 - 0.049 13.3 4.1 0.096 12.4 2.8 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-HC5HC2H_2 PF13832.1 KFM10243.1 - 0.05 13.6 2.8 0.097 12.6 1.9 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-C3HC4_4 PF15227.1 KFM10243.1 - 0.15 11.9 4.1 0.41 10.5 2.9 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-HC5HC2H PF13771.1 KFM10243.1 - 0.18 11.9 3.8 0.46 10.6 2.6 1.7 1 1 0 1 1 1 0 PHD-like zinc-binding domain FANCL_C PF11793.3 KFM10243.1 - 0.34 10.8 9.3 8.2 6.4 6.4 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain Fz PF01392.17 KFM10244.1 - 1.2e-28 99.7 2.5 1.2e-28 99.7 1.8 1.6 2 0 0 2 2 2 1 Fz domain NTR PF01759.16 KFM10244.1 - 1.3e-15 56.9 0.2 2.1e-15 56.2 0.1 1.3 1 0 0 1 1 1 1 UNC-6/NTR/C345C module Chlam_OMP6 PF03504.8 KFM10244.1 - 0.048 13.9 0.0 0.099 12.9 0.0 1.5 1 0 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 6 Yae1_N PF09811.4 KFM10246.1 - 1.6e-10 40.3 20.3 0.0013 18.2 14.1 2.6 1 1 0 1 1 1 1 Essential protein Yae1, N terminal Cadherin PF00028.12 KFM10248.1 - 2.8e-100 328.7 5.4 4.2e-20 71.7 0.0 7.1 7 0 0 7 7 7 6 Cadherin domain Cadherin_2 PF08266.7 KFM10248.1 - 1.1e-07 31.2 0.1 2.8 7.5 0.0 6.0 5 1 0 5 5 5 3 Cadherin-like Cadherin_pro PF08758.6 KFM10248.1 - 5.8e-05 22.7 0.0 5.9 6.7 0.0 4.5 4 0 0 4 4 4 2 Cadherin prodomain like WD40 PF00400.27 KFM10249.1 - 1.2e-54 180.3 20.1 1.9e-11 43.3 0.4 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KFM10249.1 - 4.4e-06 25.7 0.1 0.34 9.5 0.0 3.4 1 1 2 3 3 3 3 Nup133 N terminal like BBS2_Mid PF14783.1 KFM10249.1 - 0.00033 20.4 0.1 3.2 7.5 0.0 4.4 3 1 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 KFM10249.1 - 0.00047 18.4 5.9 0.079 11.0 1.0 3.7 1 1 2 4 4 4 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KFM10249.1 - 0.058 12.8 1.3 2.8 7.3 0.9 2.6 1 1 0 1 1 1 0 PQQ-like domain Fibrinogen_C PF00147.13 KFM10250.1 - 2.5e-109 364.3 15.8 3.8e-109 363.7 10.9 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Fib_alpha PF08702.5 KFM10250.1 - 2e-41 141.4 3.4 2.8e-41 141.0 2.3 1.2 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family DUF1465 PF07323.7 KFM10250.1 - 0.048 13.2 0.7 1.9 8.0 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) Bacillus_HBL PF05791.6 KFM10250.1 - 0.22 10.8 5.9 0.21 10.9 2.5 1.9 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Fibrinogen_C PF00147.13 KFM10251.1 - 7.3e-63 212.3 5.2 8.1e-63 212.1 3.6 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Fib_alpha PF08702.5 KFM10252.1 - 1.5e-43 148.4 5.6 1.5e-43 148.4 3.9 2.0 1 1 1 2 2 2 1 Fibrinogen alpha/beta chain family Fibrinogen_C PF00147.13 KFM10253.1 - 1.3e-42 146.0 0.3 1.4e-42 145.8 0.2 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DUF1446 PF07287.6 KFM10254.1 - 2.6e-103 345.3 0.0 2.9e-103 345.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) LRAT PF04970.8 KFM10255.1 - 2.9e-22 78.9 0.0 3.9e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Lecithin retinol acyltransferase RRM_1 PF00076.17 KFM10256.1 - 4.8e-36 122.2 2.1 8.2e-14 51.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM10256.1 - 5.1e-29 100.0 0.8 8.7e-10 38.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DND1_DSRM PF14709.1 KFM10256.1 - 7.2e-26 90.2 0.0 5.4e-25 87.4 0.0 2.2 2 0 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 RRM_5 PF13893.1 KFM10256.1 - 2.7e-17 62.3 0.7 7.3e-06 25.7 0.1 3.7 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 7tm_1 PF00001.16 KFM10257.1 - 1e-53 182.1 15.0 1.4e-53 181.6 10.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM10257.1 - 1.7e-15 56.8 13.8 2.4e-15 56.4 9.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM10257.1 - 0.00077 18.6 10.0 0.00077 18.6 6.9 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF4131 PF13567.1 KFM10257.1 - 0.062 12.6 0.1 0.062 12.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF4207 PF13904.1 KFM10258.1 - 0.00013 21.4 83.5 0.00061 19.2 32.4 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4207) TolB_N PF04052.8 KFM10258.1 - 5.1 7.2 6.5 1.8 8.7 0.5 2.9 2 1 1 3 3 3 0 TolB amino-terminal domain Guanylate_cyc PF00211.15 KFM10259.1 - 1.2e-61 207.3 0.0 2e-61 206.6 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.9 KFM10259.1 - 1.6e-61 207.2 2.6 2e-60 203.7 1.8 2.2 1 1 0 1 1 1 1 Heme NO binding associated HNOB PF07700.10 KFM10259.1 - 4.4e-07 29.5 0.0 7.5e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Heme NO binding HNOBA PF07701.9 KFM10260.1 - 6.7e-73 244.5 0.0 1.2e-72 243.7 0.0 1.4 1 0 0 1 1 1 1 Heme NO binding associated Guanylate_cyc PF00211.15 KFM10260.1 - 2.8e-65 219.1 0.0 4.2e-65 218.5 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOB PF07700.10 KFM10260.1 - 9.9e-52 174.9 0.1 1.5e-51 174.2 0.0 1.3 1 0 0 1 1 1 1 Heme NO binding ASC PF00858.19 KFM10261.1 - 1.3e-100 337.1 4.9 1.5e-100 336.9 3.4 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Trp_dioxygenase PF03301.8 KFM10262.1 - 3.2e-164 546.0 4.9 3.8e-164 545.8 3.4 1.0 1 0 0 1 1 1 1 Tryptophan 2,3-dioxygenase Peptidase_C1 PF00112.18 KFM10263.1 - 2e-58 197.8 4.3 2.3e-58 197.6 3.0 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 KFM10263.1 - 3.3e-07 29.1 0.2 0.0005 18.7 0.0 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C39_2 PF13529.1 KFM10263.1 - 0.04 14.2 0.6 0.13 12.5 0.4 1.8 1 1 0 1 1 1 0 Peptidase_C39 like family Inhibitor_I29 PF08246.7 KFM10263.1 - 0.041 14.1 0.1 0.091 13.0 0.1 1.6 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) CUB PF00431.15 KFM10264.1 - 1.8e-17 63.3 0.0 2.9e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 CUB domain PDGF PF00341.12 KFM10264.1 - 7.3e-13 48.4 12.0 1.2e-12 47.8 8.3 1.3 1 0 0 1 1 1 1 PDGF/VEGF domain Neur_chan_LBD PF02931.18 KFM10265.1 - 1.6e-53 181.0 0.1 2e-53 180.7 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFM10265.1 - 4.1e-38 131.6 2.8 1e-36 127.0 1.9 2.1 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region NfeD PF01957.13 KFM10265.1 - 0.018 15.1 0.1 0.032 14.3 0.0 1.3 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding Lig_chan PF00060.21 KFM10266.1 - 5.1e-60 201.4 0.1 8.1e-60 200.8 0.1 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel ANF_receptor PF01094.23 KFM10266.1 - 1.5e-50 171.9 0.0 3.6e-50 170.7 0.0 1.7 2 0 0 2 2 2 1 Receptor family ligand binding region Lig_chan-Glu_bd PF10613.4 KFM10266.1 - 4.1e-27 93.9 0.5 9.6e-27 92.7 0.4 1.7 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.15 KFM10266.1 - 2.1e-26 92.5 0.0 3.8e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.1 KFM10266.1 - 5e-07 29.3 0.0 5.5e-06 25.9 0.0 2.3 2 1 0 2 2 2 1 Periplasmic binding protein FAM198 PF15051.1 KFM10267.1 - 2.8e-154 512.6 1.9 3.4e-154 512.3 1.3 1.1 1 0 0 1 1 1 1 FAM198 protein DUF1632 PF07857.7 KFM10268.1 - 4.7e-96 320.9 4.8 4.7e-96 320.9 3.3 1.8 1 1 1 2 2 2 1 CEO family (DUF1632) Sugar_transport PF06800.7 KFM10268.1 - 2.1e-10 40.1 14.5 4e-10 39.2 2.1 2.6 3 0 0 3 3 3 2 Sugar transport protein Ribonuc_red_sm PF00268.16 KFM10268.1 - 0.05 12.6 0.0 0.071 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribonucleotide reductase, small chain LRR_8 PF13855.1 KFM10269.1 - 3.9e-53 177.0 57.0 9.9e-14 50.8 3.4 5.5 1 1 4 6 6 6 6 Leucine rich repeat 7tm_1 PF00001.16 KFM10269.1 - 1.7e-27 96.1 18.1 2.6e-27 95.6 12.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_4 PF12799.2 KFM10269.1 - 4e-27 93.3 34.5 9.7e-08 31.4 2.6 6.6 3 1 2 6 6 6 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFM10269.1 - 5.8e-19 68.0 7.6 3.4e-09 36.5 1.6 2.5 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_1 PF00560.28 KFM10269.1 - 7.4e-12 43.5 29.5 0.034 14.1 0.1 10.0 10 0 0 10 10 10 5 Leucine Rich Repeat LRR_9 PF14580.1 KFM10269.1 - 7.7e-08 32.0 10.9 0.0085 15.6 0.2 3.7 1 1 3 4 4 4 4 Leucine-rich repeat Ldl_recept_a PF00057.13 KFM10269.1 - 3.1e-07 30.1 6.5 3.1e-07 30.1 4.5 2.0 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A LRR_6 PF13516.1 KFM10269.1 - 1.6e-06 27.5 22.1 0.55 10.4 0.3 8.7 8 1 1 9 9 9 3 Leucine Rich repeat LRR_7 PF13504.1 KFM10269.1 - 1.6e-06 27.3 21.1 0.047 13.8 0.3 9.0 9 0 0 9 9 9 2 Leucine rich repeat LRRNT PF01462.13 KFM10269.1 - 0.0036 16.7 0.1 0.0095 15.3 0.0 1.7 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain ETF_QO PF05187.8 KFM10270.1 - 2.3e-44 149.8 0.0 4.1e-44 149.0 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 KFM10270.1 - 2.8e-10 39.6 0.8 8.5e-05 21.6 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFM10270.1 - 4.4e-08 32.4 0.7 5e-05 22.3 0.7 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 KFM10270.1 - 1.5e-07 30.7 0.0 2e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 KFM10270.1 - 6.1e-07 29.3 0.1 3.4e-06 26.9 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KFM10270.1 - 1.4e-05 24.3 0.1 3.3e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KFM10270.1 - 1.9e-05 24.6 0.1 3.6e-05 23.7 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFM10270.1 - 3.8e-05 23.5 0.0 0.00013 21.7 0.1 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KFM10270.1 - 7.9e-05 21.7 0.1 0.00011 21.2 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 KFM10270.1 - 0.00022 19.8 0.4 0.00033 19.2 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 KFM10270.1 - 0.00088 19.3 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KFM10270.1 - 0.0018 16.9 0.1 0.033 12.8 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase FAD_oxidored PF12831.2 KFM10270.1 - 0.0044 16.1 0.0 0.0068 15.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFM10270.1 - 0.01 16.2 0.1 1.2 9.5 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFM10270.1 - 0.026 13.4 0.0 0.037 12.9 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 KFM10270.1 - 0.033 13.0 0.2 0.054 12.3 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Fer4_7 PF12838.2 KFM10270.1 - 0.061 13.7 0.5 0.16 12.3 0.4 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Pro_isomerase PF00160.16 KFM10271.1 - 2.4e-41 141.5 0.4 2.6e-41 141.3 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.1 KFM10271.1 - 0.08 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain FNIP_M PF14637.1 KFM10272.1 - 2.4e-89 298.9 0.5 4.5e-89 298.0 0.3 1.5 1 0 0 1 1 1 1 Folliculin-interacting protein middle domain FNIP_C PF14638.1 KFM10272.1 - 4.6e-70 234.9 0.5 1.7e-69 233.0 0.4 1.9 2 0 0 2 2 2 1 Folliculin-interacting protein C-terminus FNIP_N PF14636.1 KFM10272.1 - 2.9e-38 131.2 0.7 2.9e-38 131.2 0.5 3.1 3 1 0 3 3 3 1 Folliculin-interacting protein N-terminus RasGEF_N PF00618.15 KFM10273.1 - 4.5e-18 65.2 0.2 1.2e-17 63.8 0.1 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif RA PF00788.18 KFM10273.1 - 4.8e-11 43.0 0.0 1.3e-10 41.6 0.0 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PDZ PF00595.19 KFM10273.1 - 1.1e-10 41.5 0.0 2.4e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) cNMP_binding PF00027.24 KFM10273.1 - 1.5e-07 31.1 0.1 6.8e-06 25.8 0.0 2.7 2 1 0 2 2 2 1 Cyclic nucleotide-binding domain PDZ_2 PF13180.1 KFM10273.1 - 3.6e-05 23.5 0.0 0.00012 21.8 0.0 1.9 1 0 0 1 1 1 1 PDZ domain IF4E PF01652.13 KFM10274.1 - 2.9e-34 117.9 0.0 3.4e-34 117.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Ago_hook PF10427.4 KFM10274.1 - 0.073 13.1 0.4 0.14 12.1 0.0 1.5 2 0 0 2 2 2 0 Argonaute hook 7tm_1 PF00001.16 KFM10275.1 - 1.4e-33 116.0 11.4 2e-33 115.6 7.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Prokineticin PF06607.6 KFM10276.1 - 1e-39 134.5 9.9 1.1e-39 134.4 6.8 1.0 1 0 0 1 1 1 1 Prokineticin zf-RanBP PF00641.13 KFM10277.1 - 1.5e-08 33.5 2.4 3e-08 32.6 1.7 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others MIP-T3 PF10243.4 KFM10277.1 - 6.2 5.1 28.9 7.8 4.8 20.0 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Macoilin PF09726.4 KFM10277.1 - 6.7 4.8 22.6 8.4 4.5 15.7 1.1 1 0 0 1 1 1 0 Transmembrane protein SHQ1 PF04925.10 KFM10278.1 - 5.5e-67 224.9 0.9 9.6e-67 224.1 0.6 1.3 1 0 0 1 1 1 1 SHQ1 protein PIH1 PF08190.7 KFM10278.1 - 0.024 14.0 0.8 0.23 10.8 0.0 2.2 2 0 0 2 2 2 0 pre-RNA processing PIH1/Nop17 TLP-20 PF06088.6 KFM10278.1 - 0.037 13.6 0.4 0.093 12.3 0.3 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Mrr_N PF14338.1 KFM10278.1 - 0.14 12.3 2.2 1.3 9.1 0.0 3.1 3 0 0 3 3 3 0 Mrr N-terminal domain Glyco_transf_8 PF01501.15 KFM10279.1 - 2e-15 56.8 0.1 4.4e-15 55.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 PPP4R2 PF09184.6 KFM10280.1 - 4.5e-90 302.0 0.2 4.5e-90 302.0 0.2 2.4 1 1 1 2 2 2 1 PPP4R2 PDZ PF00595.19 KFM10281.1 - 2.7e-19 69.1 0.8 1.9e-14 53.5 0.0 2.5 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM10281.1 - 7.2e-07 29.0 0.4 2.8e-06 27.1 0.0 2.1 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.1 KFM10281.1 - 0.0037 17.0 0.0 0.0096 15.6 0.0 1.7 1 0 0 1 1 1 1 Tricorn protease PDZ domain PDZ PF00595.19 KFM10282.1 - 4.5e-08 33.1 0.2 7.6e-08 32.4 0.2 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) zf-C3HC4 PF00097.20 KFM10282.1 - 2.7e-07 30.1 6.5 7.7e-07 28.6 4.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM10282.1 - 2.9e-07 30.3 8.3 8.8e-07 28.8 5.8 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM10282.1 - 6.5e-07 29.0 10.0 6.6e-07 29.0 5.7 2.0 2 0 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.1 KFM10282.1 - 1.3e-06 28.0 6.7 1.3e-06 28.0 4.7 2.0 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFM10282.1 - 5e-06 26.0 5.5 1.2e-05 24.8 3.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFM10282.1 - 3e-05 23.7 8.2 8.1e-05 22.4 5.7 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Sina PF03145.11 KFM10282.1 - 3.2e-05 23.6 0.8 5e-05 23.0 0.4 1.6 1 1 0 1 1 1 1 Seven in absentia protein family zf-RING_6 PF14835.1 KFM10282.1 - 0.0032 17.1 2.5 0.0032 17.1 1.7 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein U-box PF04564.10 KFM10282.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 U-box domain Prok-RING_4 PF14447.1 KFM10282.1 - 0.021 14.3 5.5 0.072 12.6 3.8 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.2 KFM10282.1 - 0.024 14.7 2.8 0.074 13.1 2.0 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger PDZ_2 PF13180.1 KFM10282.1 - 0.027 14.3 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Foamy_BEL PF03274.9 KFM10282.1 - 0.076 12.2 0.4 0.17 11.0 0.3 1.6 1 1 0 1 1 1 0 Foamy virus BEL 1/2 protein zf-RING_UBOX PF13445.1 KFM10282.1 - 0.13 11.9 6.3 0.36 10.5 4.4 1.8 1 0 0 1 1 1 0 RING-type zinc-finger I-set PF07679.11 KFM10283.1 - 3e-68 225.7 0.0 9.6e-16 57.4 0.0 6.5 6 0 0 6 6 6 5 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM10283.1 - 1.6e-49 165.9 0.0 6.5e-10 38.9 0.0 5.6 5 0 0 5 5 5 5 Immunoglobulin domain fn3 PF00041.16 KFM10283.1 - 3.8e-41 139.0 18.3 8.7e-16 57.8 1.5 4.4 4 0 0 4 4 4 4 Fibronectin type III domain ig PF00047.20 KFM10283.1 - 1e-31 108.7 1.0 3.6e-07 30.2 0.0 7.9 7 1 0 7 7 7 5 Immunoglobulin domain V-set PF07686.12 KFM10283.1 - 1.7e-31 108.4 3.4 1.3e-05 25.0 0.0 8.2 7 2 0 7 7 7 5 Immunoglobulin V-set domain Ig_3 PF13927.1 KFM10283.1 - 5.7e-29 100.3 7.0 1.5e-07 31.7 0.0 8.2 9 0 0 9 9 9 5 Immunoglobulin domain Tissue_fac PF01108.12 KFM10283.1 - 1.6e-06 27.8 3.9 0.0011 18.6 0.3 3.3 2 1 1 3 3 3 2 Tissue factor Sp38 PF07354.7 KFM10283.1 - 0.0011 17.7 0.1 3.2 6.3 0.0 4.1 5 0 0 5 5 5 1 Zona-pellucida-binding protein (Sp38) C2-set_2 PF08205.7 KFM10283.1 - 0.014 15.3 10.5 1.8 8.4 0.0 5.1 5 1 0 5 5 5 0 CD80-like C2-set immunoglobulin domain Interfer-bind PF09294.5 KFM10283.1 - 0.057 13.4 0.1 4.7 7.3 0.0 3.2 3 0 0 3 3 3 0 Interferon-alpha/beta receptor, fibronectin type III RVT_1 PF00078.22 KFM10284.1 - 0.021 14.1 0.0 0.038 13.3 0.0 1.4 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) I-set PF07679.11 KFM10285.1 - 4.3e-68 225.2 0.5 1.1e-12 47.6 0.0 7.3 8 0 0 8 8 8 6 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM10285.1 - 1.5e-54 182.0 0.1 1.6e-10 40.9 0.0 7.1 7 0 0 7 7 7 6 Immunoglobulin domain fn3 PF00041.16 KFM10285.1 - 5e-53 177.1 5.2 1.1e-12 47.8 0.0 5.6 5 0 0 5 5 5 5 Fibronectin type III domain Ig_3 PF13927.1 KFM10285.1 - 6.3e-41 138.6 2.9 1.4e-07 31.9 0.0 7.6 7 0 0 7 7 7 6 Immunoglobulin domain ig PF00047.20 KFM10285.1 - 3.8e-30 103.7 5.5 1.4e-05 25.0 0.0 7.9 9 0 0 9 9 9 5 Immunoglobulin domain Bravo_FIGEY PF13882.1 KFM10285.1 - 4.3e-27 94.8 4.9 9.3e-27 93.7 3.4 1.6 1 0 0 1 1 1 1 Bravo-like intracellular region V-set PF07686.12 KFM10285.1 - 7e-26 90.3 2.6 0.00015 21.6 0.0 7.8 4 4 1 5 5 5 5 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM10285.1 - 1.4e-07 31.2 5.0 0.33 10.8 0.0 6.7 9 0 0 9 9 9 2 CD80-like C2-set immunoglobulin domain C2-set PF05790.10 KFM10285.1 - 0.00032 20.5 0.1 14 5.7 0.0 4.3 4 0 0 4 4 4 1 Immunoglobulin C2-set domain Receptor_2B4 PF11465.3 KFM10285.1 - 0.00059 19.7 0.6 12 5.8 0.0 4.3 3 1 1 4 4 4 1 Natural killer cell receptor 2B4 HAD PF12710.2 KFM10286.1 - 1.9e-16 60.7 0.0 3.6e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KFM10286.1 - 2.4e-16 59.4 0.1 7.1e-16 57.9 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KFM10286.1 - 4.1e-12 46.9 0.7 3.5e-08 34.1 0.5 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFM10286.1 - 6e-09 35.7 0.0 1.6e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFM10286.1 - 0.00045 19.8 0.0 0.00097 18.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ATP-synt_8 PF00895.15 KFM10286.1 - 0.31 11.2 4.0 6.8 6.9 0.0 4.0 3 0 0 3 3 3 0 ATP synthase protein 8 MIP PF00230.15 KFM10287.1 - 5.6e-43 147.0 8.0 7.1e-43 146.6 5.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF3697 PF12478.3 KFM10288.1 - 1.9e-19 68.9 0.2 4.9e-19 67.6 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin-associated protein 2 UBA PF00627.26 KFM10288.1 - 0.00025 20.8 0.0 0.00051 19.7 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 KFM10288.1 - 0.00031 20.2 0.0 0.00063 19.2 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Methyltransf_32 PF13679.1 KFM10288.1 - 0.055 13.1 0.3 0.13 11.9 0.2 1.5 1 0 0 1 1 1 0 Methyltransferase domain CUE PF02845.11 KFM10288.1 - 0.092 12.2 1.4 0.28 10.7 0.1 2.2 2 0 0 2 2 2 0 CUE domain NICE-3 PF07406.6 KFM10289.1 - 1.8e-69 232.9 0.1 2.5e-69 232.5 0.0 1.2 1 0 0 1 1 1 1 NICE-3 protein UDPG_MGDP_dh_N PF03721.9 KFM10289.1 - 0.17 11.2 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Tropomyosin PF00261.15 KFM10290.1 - 7.4e-107 355.8 88.7 1.2e-100 335.5 43.0 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.2 KFM10290.1 - 3.4e-39 133.9 78.8 1.1e-34 119.3 31.6 3.1 1 1 2 3 3 3 3 Tropomyosin like Laminin_II PF06009.7 KFM10290.1 - 1.5e-08 34.4 33.3 7.5e-06 25.7 4.9 3.7 1 1 3 4 4 4 3 Laminin Domain II TMF_DNA_bd PF12329.3 KFM10290.1 - 3.4e-05 23.5 9.9 3.4e-05 23.5 6.9 5.8 1 1 5 6 6 5 2 TATA element modulatory factor 1 DNA binding IncA PF04156.9 KFM10290.1 - 0.00058 19.5 62.7 0.0011 18.6 18.6 3.0 1 1 1 2 2 1 1 IncA protein WEMBL PF05701.6 KFM10290.1 - 0.0071 14.8 71.5 0.015 13.7 13.5 3.3 1 1 2 3 3 3 2 Weak chloroplast movement under blue light CENP-F_leu_zip PF10473.4 KFM10290.1 - 0.0077 16.0 30.6 0.0077 16.0 21.2 2.2 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 KFM10290.1 - 0.0098 15.1 8.3 0.028 13.5 0.5 2.1 2 0 0 2 2 2 1 Reovirus sigma C capsid protein ATG16 PF08614.6 KFM10290.1 - 0.01 15.6 9.8 0.01 15.6 6.8 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) AAA_13 PF13166.1 KFM10290.1 - 0.022 13.2 52.1 0.097 11.1 20.9 2.0 1 1 1 2 2 2 0 AAA domain MscS_porin PF12795.2 KFM10290.1 - 0.023 14.0 51.0 0.13 11.5 12.2 3.1 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain SlyX PF04102.7 KFM10290.1 - 0.045 14.1 38.9 0.11 12.9 0.4 5.6 2 2 2 5 5 5 0 SlyX Myosin_tail_1 PF01576.14 KFM10290.1 - 0.07 10.8 71.6 0.0032 15.2 20.7 2.4 1 1 1 2 2 2 0 Myosin tail Nup54 PF13874.1 KFM10290.1 - 0.099 12.3 37.5 0.36 10.5 1.5 4.2 1 1 2 4 4 4 0 Nucleoporin complex subunit 54 gpW PF02831.10 KFM10290.1 - 0.16 11.5 3.0 2.9 7.5 0.0 3.4 2 1 1 3 3 3 0 gpW DUF869 PF05911.6 KFM10290.1 - 0.21 9.7 55.1 0.81 7.8 21.4 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) ADIP PF11559.3 KFM10290.1 - 0.23 11.3 53.7 0.35 10.7 10.3 3.8 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding NPV_P10 PF05531.7 KFM10290.1 - 0.78 10.0 16.0 2.2 8.5 0.5 4.4 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein EzrA PF06160.7 KFM10290.1 - 0.82 7.7 49.8 3 5.9 13.0 3.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Laminin_I PF06008.9 KFM10290.1 - 0.88 8.8 58.1 0.35 10.1 9.0 3.1 1 1 2 3 3 3 0 Laminin Domain I DUF2514 PF10721.4 KFM10290.1 - 1.2 8.7 44.8 4.1 7.0 22.3 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2514) Baculo_PEP_C PF04513.7 KFM10290.1 - 1.7 8.4 16.7 7.7 6.3 2.6 3.8 2 2 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus RmuC PF02646.11 KFM10290.1 - 1.7 7.4 32.8 0.25 10.1 4.0 3.8 1 1 3 4 4 4 0 RmuC family Fib_alpha PF08702.5 KFM10290.1 - 2.9 8.0 32.1 1.1 9.3 4.7 3.2 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF4200 PF13863.1 KFM10290.1 - 3.2 7.7 73.3 0.59 10.0 21.3 4.4 1 1 2 3 3 2 0 Domain of unknown function (DUF4200) WD40_alt PF14077.1 KFM10290.1 - 3.5 7.3 7.1 4.3 7.0 0.4 3.4 3 0 0 3 3 2 0 Alternative WD40 repeat motif ERM PF00769.14 KFM10290.1 - 4.2 6.8 74.2 0.3 10.5 15.7 2.9 1 1 2 3 3 3 0 Ezrin/radixin/moesin family APG6 PF04111.7 KFM10290.1 - 5.6 5.9 67.6 5.9 5.8 18.6 3.1 1 1 2 3 3 3 0 Autophagy protein Apg6 AAA_27 PF13514.1 KFM10290.1 - 6 4.4 58.4 16 3.0 40.5 1.7 1 1 0 1 1 1 0 AAA domain DUF1664 PF07889.7 KFM10290.1 - 7.1 6.4 32.2 7.1 6.4 3.2 4.2 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) TRAP_beta PF05753.9 KFM10291.1 - 3.6e-70 234.8 0.0 4.2e-70 234.5 0.0 1.0 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) NCU-G1 PF15065.1 KFM10292.1 - 5.8e-103 344.2 0.0 7.1e-103 343.9 0.0 1.0 1 0 0 1 1 1 1 Lysosomal transcription factor, NCU-G1 MAPEG PF01124.13 KFM10293.1 - 1.5e-06 27.8 4.9 2.5e-06 27.1 3.4 1.4 1 0 0 1 1 1 1 MAPEG family DUF4149 PF13664.1 KFM10293.1 - 1.6 8.8 8.9 8.8 6.4 6.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4149) HlyIII PF03006.15 KFM10294.1 - 1.2e-27 96.7 14.5 1.4e-27 96.5 10.0 1.0 1 0 0 1 1 1 1 Haemolysin-III related NHase_alpha PF02979.11 KFM10294.1 - 0.053 12.7 0.1 0.64 9.2 0.1 2.0 2 0 0 2 2 2 0 Nitrile hydratase, alpha chain Nnf1 PF03980.9 KFM10295.1 - 9.1e-29 99.6 0.4 1.4e-28 99.0 0.3 1.3 1 0 0 1 1 1 1 Nnf1 AAA_16 PF13191.1 KFM10295.1 - 0.011 15.7 0.1 0.021 14.8 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain RapA_C PF12137.3 KFM10295.1 - 0.018 13.8 1.1 0.73 8.5 0.1 2.0 2 0 0 2 2 2 0 RNA polymerase recycling family C-terminal Erp_C PF06780.6 KFM10295.1 - 0.025 14.4 2.3 0.11 12.3 0.1 2.1 1 1 1 2 2 2 0 Erp protein C-terminus AAA_23 PF13476.1 KFM10295.1 - 0.031 14.6 1.0 0.036 14.3 0.7 1.1 1 0 0 1 1 1 0 AAA domain CASP_C PF08172.7 KFM10295.1 - 0.077 12.0 1.0 0.096 11.6 0.7 1.1 1 0 0 1 1 1 0 CASP C terminal DUF2009 PF09418.5 KFM10295.1 - 0.083 11.6 0.2 0.1 11.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) Med28 PF11594.3 KFM10295.1 - 0.13 12.4 1.4 0.4 10.9 1.0 1.8 1 1 0 1 1 1 0 Mediator complex subunit 28 CDC37_N PF03234.9 KFM10295.1 - 0.37 11.1 3.4 1.9 8.7 0.2 1.8 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding IncA PF04156.9 KFM10295.1 - 0.61 9.6 3.5 3 7.4 0.2 2.0 2 0 0 2 2 2 0 IncA protein Mito_carr PF00153.22 KFM10296.1 - 8.5e-51 169.6 7.2 2.6e-16 59.1 0.2 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein NPR2 PF06218.6 KFM10296.1 - 0.0094 14.6 0.3 0.05 12.3 0.0 1.9 2 0 0 2 2 2 1 Nitrogen permease regulator 2 Sema PF01403.14 KFM10297.1 - 2.3e-121 405.3 0.0 2.7e-121 405.1 0.0 1.0 1 0 0 1 1 1 1 Sema domain PSI PF01437.20 KFM10297.1 - 0.23 11.6 2.1 0.54 10.4 1.4 1.7 1 0 0 1 1 1 0 Plexin repeat Filament PF00038.16 KFM10298.1 - 3.8e-94 315.6 58.8 5.3e-94 315.2 40.7 1.2 1 0 0 1 1 1 1 Intermediate filament protein LTD PF00932.14 KFM10298.1 - 2.6e-17 62.9 0.1 4.3e-17 62.2 0.1 1.3 1 0 0 1 1 1 1 Lamin Tail Domain Myosin_tail_1 PF01576.14 KFM10298.1 - 9.8e-05 20.2 71.0 0.0087 13.8 14.0 3.1 1 1 2 3 3 3 3 Myosin tail DUF869 PF05911.6 KFM10298.1 - 0.0011 17.3 12.3 0.0011 17.3 8.5 3.2 1 1 2 3 3 3 2 Plant protein of unknown function (DUF869) CENP-F_leu_zip PF10473.4 KFM10298.1 - 0.01 15.6 64.3 0.027 14.3 15.6 3.8 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 KFM10298.1 - 0.011 14.8 15.1 0.053 12.7 2.2 3.1 1 1 3 4 4 4 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 KFM10298.1 - 0.17 11.5 58.3 1.5 8.5 15.8 3.9 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 KFM10298.1 - 0.23 11.0 73.4 0.061 12.9 8.8 4.1 1 1 3 4 4 4 0 IncA protein Baculo_PEP_C PF04513.7 KFM10298.1 - 8.1 6.2 17.9 1.7 8.4 1.8 3.6 1 1 4 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus KH_1 PF00013.24 KFM10299.1 - 1e-20 73.1 1.9 1.7e-14 53.2 0.3 2.3 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 KFM10299.1 - 2.6e-11 42.8 0.2 2.4e-07 30.2 0.1 2.5 2 0 0 2 2 2 2 KH domain zf-C3HC4_3 PF13920.1 KFM10299.1 - 2.1e-05 24.0 2.0 3.4e-05 23.4 1.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM10299.1 - 0.012 15.5 2.4 0.022 14.7 1.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) KH_2 PF07650.12 KFM10299.1 - 0.021 14.3 0.0 0.057 12.9 0.0 1.7 1 0 0 1 1 1 0 KH domain Ras PF00071.17 KFM10300.1 - 6e-61 204.5 0.1 7e-61 204.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM10300.1 - 3.7e-19 69.3 0.0 5.3e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM10300.1 - 1.1e-11 44.2 0.0 1.3e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFM10300.1 - 2.2e-07 30.8 0.1 3.6e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KFM10300.1 - 5.3e-06 26.6 0.0 1.8e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 KFM10300.1 - 0.00019 20.9 0.0 0.00035 20.0 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KFM10300.1 - 0.0018 17.4 0.0 0.0063 15.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_15 PF13175.1 KFM10300.1 - 0.0019 17.3 0.0 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 KFM10300.1 - 0.0022 17.9 0.0 0.0035 17.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 KFM10300.1 - 0.0032 16.6 0.1 0.0058 15.8 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 KFM10300.1 - 0.014 15.3 0.3 0.038 13.9 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.5 KFM10300.1 - 0.022 13.9 0.0 0.037 13.2 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 KFM10300.1 - 0.035 14.4 0.1 0.048 13.9 0.1 1.5 1 1 0 1 1 1 0 ABC transporter FeoB_N PF02421.13 KFM10300.1 - 0.058 12.6 0.1 0.17 11.1 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_5 PF07728.9 KFM10300.1 - 0.14 11.9 0.0 0.41 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Ras PF00071.17 KFM10301.1 - 1.7e-55 186.8 1.0 8.5e-55 184.5 0.7 1.8 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KFM10301.1 - 1.3e-17 64.3 0.1 1.7e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM10301.1 - 2e-11 43.4 0.1 2.7e-11 43.0 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFM10301.1 - 1.7e-06 27.9 0.1 2.2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KFM10301.1 - 4.9e-05 23.4 0.0 0.00017 21.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 KFM10301.1 - 0.00028 20.1 0.0 0.00035 19.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.11 KFM10301.1 - 0.00041 19.5 0.0 0.0031 16.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 KFM10301.1 - 0.00091 18.5 1.1 0.021 14.0 0.8 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KFM10301.1 - 0.0011 18.4 0.3 0.0033 16.9 0.2 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 KFM10301.1 - 0.0054 16.2 0.1 0.025 14.0 0.0 2.0 2 1 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 KFM10301.1 - 0.0074 15.3 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Septin SRPRB PF09439.5 KFM10301.1 - 0.011 14.9 0.1 0.075 12.2 0.0 2.0 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit AAA_15 PF13175.1 KFM10301.1 - 0.016 14.3 0.0 0.016 14.2 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain cobW PF02492.14 KFM10301.1 - 0.018 14.4 0.1 1 8.7 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 KFM10301.1 - 0.021 14.5 0.1 0.037 13.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KFM10301.1 - 0.026 14.4 0.0 0.075 12.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KFM10301.1 - 0.031 14.2 0.2 0.71 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KFM10301.1 - 0.038 14.2 0.1 0.051 13.8 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 KFM10301.1 - 0.075 13.0 0.1 0.1 12.5 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.1 KFM10301.1 - 0.086 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KFM10301.1 - 0.089 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 KFM10301.1 - 0.1 12.9 0.1 0.27 11.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 KFM10301.1 - 0.11 11.4 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain Robl_LC7 PF03259.12 KFM10302.1 - 2.8e-13 49.2 0.1 3.4e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain Glycos_trans_3N PF02885.12 KFM10302.1 - 0.019 14.5 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain ubiquitin PF00240.18 KFM10303.1 - 2.3e-13 49.3 0.2 3.8e-13 48.6 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 KFM10303.1 - 6.6e-07 28.9 0.5 6.6e-07 28.9 0.3 2.3 3 0 0 3 3 3 1 UBA/TS-N domain Rad60-SLD PF11976.3 KFM10303.1 - 0.00014 21.4 0.1 0.00025 20.6 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Arm_2 PF04826.8 KFM10303.1 - 0.024 13.7 0.2 0.024 13.7 0.1 2.6 3 0 0 3 3 3 0 Armadillo-like Rad60-SLD_2 PF13881.1 KFM10303.1 - 0.033 14.0 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like ComX PF05952.7 KFM10303.1 - 0.081 12.4 4.3 11 5.6 0.0 4.1 2 2 2 4 4 4 0 Bacillus competence pheromone ComX Herpes_Helicase PF02689.9 KFM10303.1 - 0.2 9.3 0.2 0.28 8.8 0.1 1.1 1 0 0 1 1 1 0 Helicase Kinesin-relat_1 PF12711.2 KFM10303.1 - 0.44 10.9 14.2 8.1 6.9 1.2 4.3 2 1 1 3 3 3 0 Kinesin motor Pik1 PF11522.3 KFM10303.1 - 0.65 9.7 0.0 0.65 9.7 0.0 3.2 4 0 0 4 4 4 0 Yeast phosphatidylinositol-4-OH kinase Pik1 Clathrin-link PF09268.5 KFM10303.1 - 6.1 5.9 9.1 35 3.5 0.2 3.9 3 0 0 3 3 3 0 Clathrin, heavy-chain linker Ras_bdg_2 PF14847.1 KFM10304.1 - 0.032 14.1 0.0 0.032 14.1 0.0 1.2 1 0 0 1 1 1 0 Ras-binding domain of Byr2 YjeF_N PF03853.10 KFM10305.1 - 3.7e-33 114.4 0.0 4.7e-33 114.1 0.0 1.0 1 0 0 1 1 1 1 YjeF-related protein N-terminus TPR_12 PF13424.1 KFM10306.1 - 1e-22 79.8 18.8 2.2e-06 27.5 5.3 5.9 1 1 6 8 8 8 7 Tetratricopeptide repeat TPR_1 PF00515.23 KFM10306.1 - 2.1e-20 71.3 18.7 0.00035 20.0 0.0 8.3 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.1 KFM10306.1 - 4.7e-20 71.0 20.4 6.5e-06 25.6 0.0 6.2 3 2 4 7 7 7 6 TPR repeat TPR_2 PF07719.12 KFM10306.1 - 1.6e-19 68.1 24.2 0.00084 19.0 0.0 8.3 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_7 PF13176.1 KFM10306.1 - 7.1e-18 62.9 10.6 0.0068 16.1 0.2 8.3 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 KFM10306.1 - 4.5e-11 41.7 0.2 2 8.4 0.1 8.2 8 1 0 8 8 8 1 Tetratricopeptide repeat SNAP PF14938.1 KFM10306.1 - 3.1e-07 29.8 10.1 0.00022 20.4 1.4 2.5 2 1 0 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_14 PF13428.1 KFM10306.1 - 1.2e-05 25.4 26.1 1.5 9.6 0.0 8.3 3 3 6 9 9 9 2 Tetratricopeptide repeat TPR_10 PF13374.1 KFM10306.1 - 0.00051 19.8 18.1 2.1 8.3 0.5 6.4 6 1 1 7 7 7 3 Tetratricopeptide repeat Apc3 PF12895.2 KFM10306.1 - 0.00092 19.3 5.4 3.8 7.7 0.0 4.4 3 2 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 KFM10306.1 - 0.0011 19.5 31.2 0.03 15.0 0.7 5.8 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFM10306.1 - 0.0012 19.1 10.2 0.16 12.3 0.0 4.8 3 2 3 6 6 6 2 Tetratricopeptide repeat Foie-gras_1 PF11817.3 KFM10306.1 - 0.013 14.9 0.5 0.54 9.6 0.0 2.8 2 1 0 2 2 2 0 Foie gras liver health family 1 RPN7 PF10602.4 KFM10306.1 - 0.018 14.4 0.0 0.48 9.7 0.0 3.0 4 0 0 4 4 4 0 26S proteasome subunit RPN7 TPR_6 PF13174.1 KFM10306.1 - 0.14 12.6 9.0 1.4e+02 3.2 0.0 6.3 7 0 0 7 7 6 0 Tetratricopeptide repeat BTAD PF03704.12 KFM10306.1 - 4.2 7.6 17.7 2.3 8.5 0.1 4.3 3 1 0 3 3 3 0 Bacterial transcriptional activator domain RasGAP PF00616.14 KFM10307.1 - 9.8e-47 159.1 0.1 3e-46 157.5 0.0 1.9 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 KFM10307.1 - 5.9e-36 123.2 7.3 5.9e-36 123.2 5.1 2.4 3 0 0 3 3 3 1 RasGAP C-terminus IQ PF00612.22 KFM10307.1 - 1e-18 65.0 22.2 1.3e-05 24.4 1.2 5.2 4 0 0 4 4 4 4 IQ calmodulin-binding motif CH PF00307.26 KFM10307.1 - 9.3e-16 57.8 0.0 4.2e-15 55.7 0.0 2.2 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFM10307.1 - 0.0063 16.1 0.0 0.023 14.3 0.0 1.9 1 0 0 1 1 1 1 CAMSAP CH domain Prenyltrans_2 PF13249.1 KFM10307.1 - 0.0089 16.4 1.3 0.032 14.6 0.9 2.0 1 0 0 1 1 1 1 Prenyltransferase-like SRF-TF PF00319.13 KFM10308.1 - 1.5e-18 65.7 0.2 2.4e-18 65.0 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) HJURP_C PF12347.3 KFM10308.1 - 1.2e-08 34.4 0.0 1.2e-08 34.4 0.0 2.3 3 0 0 3 3 3 1 Holliday junction regulator protein family C-terminal repeat GLTT PF01744.15 KFM10308.1 - 0.36 10.2 5.0 9.5 5.7 0.1 3.1 2 1 0 2 2 2 0 GLTT repeat (6 copies) Ammonium_transp PF00909.16 KFM10309.1 - 1.1e-56 192.0 16.6 1.5e-56 191.6 11.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF1003 PF06210.6 KFM10309.1 - 0.0054 16.6 0.6 0.013 15.3 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1003) Xlink PF00193.12 KFM10310.1 - 3e-63 209.9 1.0 1.3e-33 114.9 0.1 2.2 2 0 0 2 2 2 2 Extracellular link domain V-set PF07686.12 KFM10310.1 - 8.5e-14 51.4 0.0 1.4e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 KFM10310.1 - 1.6e-07 31.0 0.0 2.9e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Chordopox_A33R PF05966.7 KFM10310.1 - 0.00024 19.9 0.3 0.024 13.3 0.1 2.1 2 0 0 2 2 2 2 Chordopoxvirus A33R protein Ig_2 PF13895.1 KFM10310.1 - 0.00053 20.0 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFM10310.1 - 0.0011 18.9 0.0 0.026 14.6 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.1 KFM10310.1 - 0.0085 16.5 0.0 0.071 13.6 0.0 2.3 1 1 0 1 1 1 1 Immunoglobulin domain Lectin_C PF00059.16 KFM10310.1 - 0.01 16.4 1.4 1.2 9.8 0.2 2.4 2 0 0 2 2 2 0 Lectin C-type domain CTDII PF01556.13 KFM10311.1 - 4.7e-22 77.6 0.1 4.6e-18 64.8 0.0 2.7 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KFM10311.1 - 5.5e-12 45.5 20.2 9.3e-12 44.8 14.0 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 KFM10311.1 - 0.0036 16.9 10.9 0.056 13.1 1.2 2.3 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family Cytochrom_c3_2 PF14537.1 KFM10311.1 - 1.8 8.9 7.3 3.6 7.9 5.1 1.6 1 0 0 1 1 1 0 Cytochrome c3 NYD-SP28 PF14772.1 KFM10312.1 - 5.6e-31 106.7 15.7 5.6e-31 106.7 10.9 5.1 3 1 2 5 5 5 1 Sperm tail NYD-SP28_assoc PF14775.1 KFM10312.1 - 1.1e-20 73.0 1.1 1.1e-20 73.0 0.8 4.3 4 0 0 4 4 4 1 Sperm tail C-terminal domain FlaC_arch PF05377.6 KFM10312.1 - 8.5 6.3 21.0 5.1 7.0 0.1 4.6 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) Stathmin PF00836.14 KFM10313.1 - 3.7e-76 253.4 22.0 4.3e-76 253.2 15.2 1.0 1 0 0 1 1 1 1 Stathmin family CDC37_N PF03234.9 KFM10313.1 - 0.19 12.0 14.6 0.24 11.6 10.1 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Phage_GPO PF05929.6 KFM10313.1 - 2.3 7.4 8.9 3.1 6.9 6.2 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Atg14 PF10186.4 KFM10313.1 - 5.1 5.9 18.7 6.9 5.5 13.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Asp-B-Hydro_N PF05279.6 KFM10313.1 - 5.8 6.6 14.4 6.8 6.4 10.0 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region ATC_hydrolase PF14196.1 KFM10313.1 - 8.5 6.7 7.8 13 6.2 5.4 1.3 1 0 0 1 1 1 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase Fibrinogen_C PF00147.13 KFM10314.1 - 2.9e-44 151.4 0.6 3.3e-44 151.2 0.4 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain ACTH_domain PF00976.13 KFM10315.1 - 5.3e-24 83.7 1.8 5.3e-24 83.7 1.3 3.1 4 0 0 4 4 4 2 Corticotropin ACTH domain Op_neuropeptide PF08035.6 KFM10315.1 - 1e-12 47.3 1.0 1.5e-12 46.8 0.0 1.8 2 0 0 2 2 2 1 Opioids neuropeptide NPP PF08384.5 KFM10315.1 - 9.6e-05 21.9 0.2 0.0002 20.8 0.2 1.6 1 0 0 1 1 1 1 Pro-opiomelanocortin, N-terminal region Ras PF00071.17 KFM10317.1 - 1.1e-36 125.7 0.1 1.4e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 Ras family DnaJ PF00226.26 KFM10317.1 - 2e-12 46.6 0.0 3.1e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Arf PF00025.16 KFM10317.1 - 3.4e-12 45.9 0.0 4.3e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 KFM10317.1 - 3.3e-11 43.7 0.0 5e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KFM10317.1 - 5.1e-06 26.0 0.0 9e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain CENP-O PF09496.5 KFM10318.1 - 9.9e-19 67.3 0.1 9.9e-19 67.3 0.1 1.9 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component Polysacc_deac_2 PF04748.8 KFM10318.1 - 0.039 12.9 0.1 3.1 6.7 0.0 2.3 2 0 0 2 2 2 0 Divergent polysaccharide deacetylase V_ATPase_I PF01496.14 KFM10318.1 - 0.1 10.4 0.2 0.12 10.2 0.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 KFM10318.1 - 0.44 10.0 5.7 0.98 8.9 3.9 1.6 1 0 0 1 1 1 0 Septum formation initiator Atg14 PF10186.4 KFM10318.1 - 0.58 9.0 5.7 0.26 10.2 1.1 2.2 3 0 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 PAS_11 PF14598.1 KFM10319.1 - 3.1e-38 130.1 0.0 6.4e-33 113.0 0.0 2.5 2 0 0 2 2 2 2 PAS domain DUF1518 PF07469.7 KFM10319.1 - 1.7e-33 114.5 41.7 3.1e-20 72.0 14.3 7.8 8 1 0 8 8 8 2 Domain of unknown function (DUF1518) SRC-1 PF08832.5 KFM10319.1 - 1.4e-26 92.9 4.1 1.4e-26 92.9 2.8 2.9 3 0 0 3 3 3 1 Steroid receptor coactivator Nuc_rec_co-act PF08815.5 KFM10319.1 - 7.1e-22 76.6 1.2 7.1e-22 76.6 0.9 2.3 3 0 0 3 3 3 1 Nuclear receptor coactivator PAS PF00989.19 KFM10319.1 - 4.3e-09 36.1 0.0 2.9e-08 33.4 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 KFM10319.1 - 2e-08 34.5 0.0 2.8e-05 24.4 0.0 2.6 2 0 0 2 2 2 2 PAS domain HLH PF00010.21 KFM10319.1 - 1.4e-05 24.6 0.5 1.4e-05 24.6 0.3 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_3 PF08447.6 KFM10319.1 - 7.7e-05 22.7 0.0 0.0048 16.9 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.5 KFM10319.1 - 0.013 15.5 0.0 0.039 14.0 0.0 1.8 1 0 0 1 1 1 0 PAS fold Pkinase PF00069.20 KFM10321.1 - 3.5e-51 173.8 0.1 2e-50 171.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM10321.1 - 5.8e-35 120.6 0.3 6.2e-26 91.0 0.0 2.6 1 1 1 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 KFM10321.1 - 0.00049 19.2 0.0 0.00091 18.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFM10321.1 - 0.0015 18.3 0.0 0.021 14.5 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KFM10321.1 - 0.0034 16.7 0.0 0.0063 15.8 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.17 KFM10321.1 - 0.035 13.4 0.0 0.094 12.0 0.0 1.6 2 0 0 2 2 2 0 RIO1 family ABC1 PF03109.11 KFM10321.1 - 0.036 14.0 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 ABC1 family DUF3091 PF11291.3 KFM10321.1 - 0.058 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3091) Radical_SAM PF04055.16 KFM10322.1 - 1.9e-19 70.4 2.1 1.8e-18 67.2 0.1 3.1 4 0 0 4 4 4 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 KFM10322.1 - 7.4e-11 41.9 0.0 2.4e-10 40.2 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KFM10322.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein F-box-like PF12937.2 KFM10323.1 - 2.8e-09 36.5 5.7 4.9e-09 35.7 4.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFM10323.1 - 2.8e-08 33.1 2.7 5.6e-08 32.2 1.8 1.5 1 0 0 1 1 1 1 F-box domain DUF4508 PF14969.1 KFM10323.1 - 0.00012 21.9 0.9 0.00023 21.1 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4508) Frizzled PF01534.12 KFM10324.1 - 2.7e-136 453.6 17.3 3.4e-136 453.3 12.0 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.17 KFM10324.1 - 2.3e-30 105.2 6.9 4.5e-30 104.3 4.8 1.5 1 0 0 1 1 1 1 Fz domain Glyco_transf_64 PF09258.5 KFM10325.1 - 1.6e-97 325.5 0.1 2.8e-97 324.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Exostosin PF03016.10 KFM10325.1 - 9.6e-53 179.1 0.0 1.4e-52 178.5 0.0 1.3 1 0 0 1 1 1 1 Exostosin family ADIP PF11559.3 KFM10325.1 - 0.0079 16.1 7.7 0.014 15.3 5.3 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Seryl_tRNA_N PF02403.17 KFM10325.1 - 0.042 13.8 5.1 0.084 12.8 3.6 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.7 KFM10325.1 - 0.047 13.4 2.5 0.094 12.5 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4140 PF13600.1 KFM10325.1 - 0.21 12.0 0.4 0.47 10.9 0.3 1.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Noelin-1 PF12308.3 KFM10325.1 - 0.41 10.4 1.9 1.1 9.1 1.2 1.7 2 0 0 2 2 2 0 Neurogenesis glycoprotein HR1 PF02185.11 KFM10325.1 - 0.42 10.3 6.2 2 8.1 2.3 2.5 2 0 0 2 2 2 0 Hr1 repeat Spc7 PF08317.6 KFM10325.1 - 0.54 8.8 6.1 1 7.9 4.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.7 KFM10325.1 - 1.8 8.2 12.4 0.23 11.2 5.8 1.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Beta-Casp PF10996.3 KFM10326.1 - 2.3e-11 43.7 0.0 4.1e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Beta-Casp domain HNF-1_N PF04814.8 KFM10327.1 - 1.3e-11 44.9 6.3 2.2e-11 44.1 1.3 2.7 2 1 0 2 2 2 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus Homeobox PF00046.24 KFM10327.1 - 1e-10 41.0 3.6 1.3e-10 40.7 0.4 2.7 3 0 0 3 3 3 1 Homeobox domain Homeobox_KN PF05920.6 KFM10327.1 - 0.00011 21.8 1.6 0.0029 17.2 0.0 3.0 3 1 0 3 3 3 1 Homeobox KN domain HTH_37 PF13744.1 KFM10327.1 - 0.00071 19.3 0.5 0.00071 19.3 0.3 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.17 KFM10327.1 - 0.0025 17.6 0.1 0.0056 16.5 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 KFM10327.1 - 0.0035 17.3 0.3 0.021 14.8 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain CUT PF02376.10 KFM10327.1 - 0.011 15.5 0.1 0.034 13.9 0.1 1.9 1 0 0 1 1 1 0 CUT domain HTH_24 PF13412.1 KFM10327.1 - 0.037 13.4 0.0 0.16 11.4 0.0 2.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_31 PF13560.1 KFM10327.1 - 0.056 13.6 2.1 0.11 12.7 0.1 2.4 3 0 0 3 3 2 0 Helix-turn-helix domain DUF494 PF04361.8 KFM10327.1 - 0.096 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF494) HTH_26 PF13443.1 KFM10327.1 - 0.12 12.5 0.0 0.38 11.0 0.0 2.0 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_23 PF13384.1 KFM10327.1 - 0.25 11.0 0.1 0.25 11.0 0.1 2.6 4 0 0 4 4 3 0 Homeodomain-like domain Pex14_N PF04695.8 KFM10327.1 - 0.35 10.9 5.9 0.19 11.7 1.7 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Kinesin PF00225.18 KFM10328.1 - 7.6e-111 370.0 0.2 1.8e-110 368.8 0.1 1.6 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 KFM10328.1 - 5.1e-27 94.2 0.1 2.4e-18 66.1 0.0 2.8 2 0 0 2 2 2 2 Kinesin protein CAP_GLY PF01302.20 KFM10328.1 - 3.3e-23 81.1 1.4 6.6e-23 80.2 1.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain KIF1B PF12423.3 KFM10328.1 - 1.1e-17 63.8 0.7 3.1e-17 62.3 0.5 1.9 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.21 KFM10328.1 - 2.5e-09 37.1 0.0 1.9e-08 34.3 0.0 2.4 2 0 0 2 2 2 1 FHA domain KMP11 PF03037.11 KFM10328.1 - 0.024 15.1 0.8 0.024 15.1 0.6 2.9 2 0 0 2 2 2 0 Kinetoplastid membrane protein 11 Yae1_N PF09811.4 KFM10329.1 - 5.7e-11 41.7 29.5 0.58 9.7 20.4 3.3 1 1 0 1 1 1 1 Essential protein Yae1, N terminal PMSR PF01625.16 KFM10331.1 - 1.1e-24 87.1 0.1 1.2e-24 86.9 0.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Arf PF00025.16 KFM10332.1 - 1.7e-58 196.6 0.0 1.9e-58 196.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KFM10332.1 - 4.6e-11 42.3 0.0 5.4e-11 42.1 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KFM10332.1 - 5.4e-09 35.2 0.2 8.8e-09 34.5 0.1 1.3 1 1 0 1 1 1 1 G-protein alpha subunit Gtr1_RagA PF04670.7 KFM10332.1 - 9.2e-08 31.5 0.0 1.1e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KFM10332.1 - 1e-06 28.1 0.0 1.2e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KFM10332.1 - 3.8e-05 24.1 0.0 5.1e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein TPR_2 PF07719.12 KFM10333.1 - 1.9e-06 27.3 0.2 0.02 14.7 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFM10333.1 - 4.8e-06 26.1 0.1 0.00043 19.8 0.0 2.3 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 KFM10333.1 - 1.9e-05 24.0 0.1 0.0019 17.7 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFM10333.1 - 0.00052 19.9 1.4 0.019 14.8 1.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 KFM10333.1 - 0.021 14.6 0.6 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 KFM10333.1 - 0.035 14.2 1.1 0.16 12.1 0.8 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 KFM10333.1 - 0.18 12.5 1.2 1.7 9.4 0.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat GDA1_CD39 PF01150.12 KFM10334.1 - 2.1e-102 342.8 0.0 2.4e-102 342.6 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family GDA1_CD39 PF01150.12 KFM10335.1 - 1.2e-98 330.5 0.0 1.4e-98 330.2 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family FAM163 PF15069.1 KFM10335.1 - 0.045 14.3 1.6 0.045 14.3 1.1 2.1 3 0 0 3 3 3 0 FAM163 family RE_TaqI PF09573.5 KFM10335.1 - 0.34 10.0 1.2 0.38 9.8 0.0 1.5 2 0 0 2 2 2 0 TaqI restriction endonuclease Adeno_E3_CR2 PF02439.10 KFM10335.1 - 0.39 10.3 3.4 0.82 9.2 2.3 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 GDA1_CD39 PF01150.12 KFM10336.1 - 2.5e-103 345.8 0.0 3.4e-103 345.4 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family zf-RING_2 PF13639.1 KFM10337.1 - 5e-11 42.2 5.5 7.1e-11 41.7 3.8 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KFM10337.1 - 4.2e-10 39.1 4.8 6.3e-10 38.6 3.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KFM10337.1 - 3.2e-09 36.3 4.6 5.5e-09 35.5 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM10337.1 - 6.6e-09 35.3 6.2 1.5e-08 34.1 4.3 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFM10337.1 - 1.3e-07 31.2 1.0 1.3e-07 31.2 0.7 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KFM10337.1 - 2.3e-07 30.5 2.5 5.7e-07 29.2 1.8 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 KFM10337.1 - 2.4e-07 30.6 5.6 4.1e-07 29.8 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KFM10337.1 - 1.6e-06 27.5 4.8 3.6e-06 26.4 3.3 1.5 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 KFM10337.1 - 0.0018 18.0 1.6 0.0026 17.5 1.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 KFM10337.1 - 0.0018 18.3 4.1 0.0027 17.7 2.2 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger DUF329 PF03884.9 KFM10337.1 - 0.012 15.1 1.3 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF329) zf-P11 PF03854.9 KFM10337.1 - 0.079 12.4 10.9 0.27 10.7 3.1 2.9 1 1 1 2 2 2 0 P-11 zinc finger DUF4428 PF14471.1 KFM10337.1 - 0.094 12.4 4.0 0.57 9.9 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) FYVE PF01363.16 KFM10337.1 - 0.29 11.0 4.1 0.49 10.3 2.6 1.6 1 1 0 1 1 1 0 FYVE zinc finger NMD3 PF04981.8 KFM10337.1 - 0.3 10.1 3.2 0.34 9.9 2.2 1.0 1 0 0 1 1 1 0 NMD3 family Baculo_IE-1 PF05290.6 KFM10337.1 - 0.42 10.3 2.9 0.57 9.9 2.0 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-CHY PF05495.7 KFM10337.1 - 0.56 10.4 3.6 1.7 8.8 2.5 1.7 1 1 1 2 2 2 0 CHY zinc finger Prok-RING_4 PF14447.1 KFM10337.1 - 0.81 9.2 11.7 5.9 6.5 0.4 3.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-Sec23_Sec24 PF04810.10 KFM10337.1 - 1.1 8.8 5.9 5.7 6.5 2.4 2.7 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger zf-MIZ PF02891.15 KFM10337.1 - 2.1 7.9 7.7 2.4 7.7 1.2 2.4 2 1 0 2 2 2 0 MIZ/SP-RING zinc finger DZR PF12773.2 KFM10337.1 - 4.3 7.2 7.5 38 4.2 5.2 2.4 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_2 PF13639.1 KFM10338.1 - 0.0011 18.7 12.3 0.0011 18.7 8.5 2.5 2 1 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KFM10338.1 - 0.006 16.2 14.2 0.006 16.2 9.9 3.0 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFM10338.1 - 0.028 14.4 14.5 0.028 14.4 10.0 3.1 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFM10338.1 - 0.15 11.7 10.3 0.23 11.2 6.0 2.2 1 1 1 2 2 2 0 RING-type zinc-finger GcpE PF04551.9 KFM10338.1 - 0.66 8.7 3.9 1.8 7.2 2.7 1.6 1 1 0 1 1 1 0 GcpE protein ADK_lid PF05191.9 KFM10338.1 - 0.75 9.5 9.1 0.28 10.9 2.2 2.8 2 1 0 2 2 2 0 Adenylate kinase, active site lid zf-C3HC4 PF00097.20 KFM10338.1 - 2.8 7.6 23.5 0.052 13.2 10.3 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 KFM10338.1 - 6.5 6.7 14.0 5.9 6.8 8.3 2.1 1 1 0 1 1 1 0 FYVE zinc finger PhnA_Zn_Ribbon PF08274.7 KFM10338.1 - 7 6.5 10.6 28 4.6 0.0 3.8 4 0 0 4 4 4 0 PhnA Zinc-Ribbon zf-RING_2 PF13639.1 KFM10339.1 - 4.1e-08 32.9 9.8 4.1e-08 32.9 6.8 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KFM10339.1 - 1.2e-06 28.0 8.0 1.2e-06 28.0 5.5 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFM10339.1 - 3e-05 23.7 5.8 3e-05 23.7 4.0 2.4 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KFM10339.1 - 7.4e-05 22.3 3.0 8.3e-05 22.2 1.2 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 KFM10339.1 - 0.00013 21.5 5.8 0.00013 21.5 4.0 2.7 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM10339.1 - 0.00081 19.3 9.8 0.00081 19.3 6.8 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFM10339.1 - 2.5 8.2 8.5 11 6.1 5.9 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger Lig_chan PF00060.21 KFM10340.1 - 1.9e-37 128.2 0.2 3.3e-37 127.4 0.1 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel ANF_receptor PF01094.23 KFM10340.1 - 7e-30 103.9 0.0 7.9e-29 100.5 0.0 2.6 1 1 0 1 1 1 1 Receptor family ligand binding region SBP_bac_3 PF00497.15 KFM10340.1 - 2.4e-21 76.0 0.0 5.8e-21 74.7 0.0 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.4 KFM10340.1 - 1.4e-19 69.8 0.0 3e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site CaM_bdg_C0 PF10562.4 KFM10340.1 - 4e-16 58.5 3.6 7.6e-16 57.6 2.5 1.5 1 0 0 1 1 1 1 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit Peripla_BP_6 PF13458.1 KFM10340.1 - 0.00015 21.2 0.0 0.0004 19.8 0.0 1.6 1 1 0 1 1 1 1 Periplasmic binding protein Ion_trans_2 PF07885.11 KFM10340.1 - 0.024 14.3 0.6 0.059 13.0 0.4 1.7 1 0 0 1 1 1 0 Ion channel zf-C2H2_6 PF13912.1 KFM10341.1 - 1.3e-10 40.8 26.9 2.8e-07 30.2 0.1 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KFM10341.1 - 2.6e-07 30.5 24.1 0.0045 17.2 1.7 5.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KFM10341.1 - 1.2e-06 28.4 28.6 0.24 11.8 2.0 5.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type Dimer_Tnp_hAT PF05699.9 KFM10341.1 - 1.8e-05 24.2 0.1 5.7e-05 22.6 0.1 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 KFM10341.1 - 0.0006 19.7 0.0 0.0015 18.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) zf-H2C2_2 PF13465.1 KFM10341.1 - 0.04 14.2 23.9 1.2 9.5 1.6 5.6 5 0 0 5 5 5 0 Zinc-finger double domain DBD_Tnp_Hermes PF10683.4 KFM10341.1 - 0.045 13.2 0.0 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain zf-met PF12874.2 KFM10341.1 - 0.066 13.4 0.5 0.066 13.4 0.3 4.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-BED PF02892.10 KFM10341.1 - 0.16 11.7 23.6 1.1 9.0 2.2 4.8 5 0 0 5 5 5 0 BED zinc finger RGS-like PF09128.6 KFM10342.1 - 6.7e-69 231.1 1.3 2.6e-68 229.2 0.0 2.5 2 1 1 3 3 3 1 Regulator of G protein signalling-like domain RhoGEF PF00621.15 KFM10342.1 - 1.9e-41 141.8 5.4 4.9e-41 140.5 3.7 1.8 1 0 0 1 1 1 1 RhoGEF domain PDZ PF00595.19 KFM10342.1 - 8.6e-15 54.6 0.3 2.1e-14 53.4 0.2 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM10342.1 - 1e-07 31.6 0.1 2.8e-07 30.3 0.1 1.7 1 0 0 1 1 1 1 PDZ domain RGS PF00615.14 KFM10342.1 - 5.3e-05 23.3 0.0 0.00016 21.7 0.0 1.9 1 0 0 1 1 1 1 Regulator of G protein signaling domain Ets PF00178.17 KFM10343.1 - 2.6e-26 91.5 0.8 3e-26 91.3 0.5 1.1 1 0 0 1 1 1 1 Ets-domain HSF_DNA-bind PF00447.12 KFM10343.1 - 0.054 13.6 0.0 0.064 13.4 0.0 1.2 1 0 0 1 1 1 0 HSF-type DNA-binding Ets PF00178.17 KFM10344.1 - 1.4e-37 127.6 3.8 2e-37 127.2 2.6 1.2 1 0 0 1 1 1 1 Ets-domain HSF_DNA-bind PF00447.12 KFM10344.1 - 0.089 12.9 0.4 0.14 12.3 0.3 1.3 1 0 0 1 1 1 0 HSF-type DNA-binding Ig_2 PF13895.1 KFM10345.1 - 2.2e-13 50.1 0.4 1.2e-05 25.3 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.11 KFM10345.1 - 2e-12 46.7 1.1 0.0047 16.7 0.1 4.0 3 2 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.1 KFM10345.1 - 4.8e-06 26.9 3.6 0.049 14.1 0.1 3.5 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.12 KFM10345.1 - 1.9e-05 24.5 0.3 1.3 8.9 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin V-set domain MLANA PF14991.1 KFM10345.1 - 0.002 18.1 0.0 0.0041 17.1 0.0 1.5 1 0 0 1 1 1 1 Protein melan-A C2-set_2 PF08205.7 KFM10345.1 - 0.0029 17.4 0.2 0.6 10.0 0.0 3.0 2 1 0 2 2 2 1 CD80-like C2-set immunoglobulin domain ig PF00047.20 KFM10345.1 - 0.016 15.3 0.1 22 5.2 0.0 4.1 4 0 0 4 4 4 0 Immunoglobulin domain Adeno_E3_CR2 PF02439.10 KFM10345.1 - 0.029 13.8 0.3 0.062 12.8 0.2 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF11 PF01345.13 KFM10345.1 - 0.14 12.2 1.8 0.65 10.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF11 Pkinase PF00069.20 KFM10346.1 - 8.2e-62 208.6 0.1 1.4e-61 207.9 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM10346.1 - 3.7e-36 124.5 0.0 5.3e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.25 KFM10346.1 - 5.8e-28 96.5 0.2 1e-27 95.7 0.2 1.4 1 0 0 1 1 1 1 C2 domain C1_1 PF00130.17 KFM10346.1 - 2.8e-17 62.1 16.2 8.4e-16 57.4 3.5 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_3 PF07649.7 KFM10346.1 - 0.025 14.6 5.6 0.025 14.6 3.8 2.8 2 0 0 2 2 2 0 C1-like domain Kinase-like PF14531.1 KFM10346.1 - 0.026 13.4 0.0 0.041 12.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KFM10346.1 - 0.16 11.6 0.0 0.38 10.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sushi PF00084.15 KFM10347.1 - 1e-41 141.0 28.0 5.8e-12 45.7 0.5 5.1 5 0 0 5 5 5 4 Sushi domain (SCR repeat) Sushi_2 PF09014.5 KFM10347.1 - 1.8e-24 85.2 1.6 1.8e-24 85.2 1.1 2.8 3 1 1 4 4 4 1 Beta-2-glycoprotein-1 fifth domain Meleagrin PF08189.6 KFM10347.1 - 0.049 13.1 8.3 3.8 7.0 0.5 4.2 4 0 0 4 4 4 0 Meleagrin/Cygnin family cEGF PF12662.2 KFM10347.1 - 0.2 11.3 4.0 6.2 6.5 0.3 3.6 2 0 0 2 2 2 0 Complement Clr-like EGF-like DUF148 PF02520.12 KFM10348.1 - 0.0044 16.8 14.6 0.0044 16.8 10.1 8.4 1 1 7 8 8 8 1 Domain of unknown function DUF148 Tup_N PF08581.5 KFM10348.1 - 0.008 16.3 12.0 0.008 16.3 8.3 11.5 4 3 8 12 12 12 2 Tup N-terminal DUF424 PF04242.8 KFM10348.1 - 0.068 13.2 5.4 0.61 10.1 0.7 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF424) DIX PF00778.12 KFM10349.1 - 8e-31 105.6 0.1 1.8e-30 104.4 0.0 1.7 1 0 0 1 1 1 1 DIX domain RGS PF00615.14 KFM10349.1 - 3.4e-27 94.9 2.1 3.4e-27 94.9 1.4 1.9 2 0 0 2 2 2 1 Regulator of G protein signaling domain Axin_b-cat_bind PF08833.5 KFM10349.1 - 4.4e-18 64.7 1.4 4.4e-18 64.7 0.9 2.5 3 0 0 3 3 3 1 Axin beta-catenin binding domain RGS PF00615.14 KFM10350.1 - 2.2e-32 111.6 0.0 4.2e-32 110.7 0.0 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.16 KFM10350.1 - 1.9e-09 37.1 0.1 9.9e-09 34.8 0.0 2.3 3 0 0 3 3 3 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) G-gamma PF00631.17 KFM10350.1 - 9.2e-08 31.7 0.0 3.1e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 GGL domain G-alpha PF00503.15 KFM10351.1 - 1.5e-117 392.5 2.7 1.7e-117 392.4 1.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KFM10351.1 - 2.3e-17 62.8 2.2 4.2e-13 48.9 0.1 3.4 3 1 0 3 3 3 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFM10351.1 - 0.00019 20.6 3.2 0.003 16.7 0.3 2.4 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFM10351.1 - 0.0048 16.3 0.1 1.1 8.6 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Miro PF08477.8 KFM10351.1 - 0.025 15.0 0.0 0.31 11.5 0.0 2.6 2 1 0 2 2 2 0 Miro-like protein MMR_HSR1 PF01926.18 KFM10351.1 - 0.026 14.4 0.0 8.6 6.3 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Ras PF00071.17 KFM10351.1 - 0.046 13.1 0.4 5.2 6.4 0.0 2.7 2 1 0 2 2 2 0 Ras family AAA_29 PF13555.1 KFM10351.1 - 0.1 12.1 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MFS_1 PF07690.11 KFM10352.1 - 1.1e-37 129.6 19.3 3.6e-36 124.6 9.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFM10352.1 - 4.2e-06 25.4 36.1 7.8e-06 24.5 8.3 3.1 2 1 1 3 3 3 3 MFS/sugar transport protein Sulfatase PF00884.18 KFM10353.1 - 4.4e-69 233.0 0.0 5.7e-69 232.6 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 KFM10353.1 - 2.2e-20 73.2 0.0 4.2e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.17 KFM10353.1 - 0.00011 21.6 0.0 0.00043 19.7 0.0 1.9 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase WD40 PF00400.27 KFM10354.1 - 1.4e-05 24.7 0.4 0.028 14.3 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat BCAS3 PF12490.3 KFM10354.1 - 0.015 14.6 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 cNMP_binding PF00027.24 KFM10355.1 - 1.5e-39 133.6 0.0 9.7e-20 70.1 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 KFM10355.1 - 4.7e-14 51.5 0.1 9.8e-14 50.5 0.1 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Cupin_2 PF07883.6 KFM10355.1 - 0.0098 15.3 1.1 1.2 8.6 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 KFM10355.1 - 0.65 9.4 3.3 6.4 6.2 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF861) DUF1193 PF06702.7 KFM10356.1 - 1.7e-98 328.4 0.0 2.1e-98 328.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1193) FAM198 PF15051.1 KFM10356.1 - 0.00065 18.4 0.2 0.0016 17.2 0.0 1.7 2 0 0 2 2 2 1 FAM198 protein PI3_PI4_kinase PF00454.22 KFM10356.1 - 0.09 12.2 1.2 0.098 12.1 0.8 1.4 1 1 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase ABC_tran PF00005.22 KFM10357.1 - 5.2e-63 211.3 0.1 3.6e-31 108.2 0.2 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 KFM10357.1 - 1.4e-32 113.1 55.9 9.7e-24 84.0 20.1 2.2 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 KFM10357.1 - 5.9e-21 75.6 6.1 1e-08 35.4 0.0 5.2 4 1 1 5 5 5 4 AAA domain DUF258 PF03193.11 KFM10357.1 - 3.8e-10 39.1 1.8 0.00018 20.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 KFM10357.1 - 1e-06 28.1 2.5 0.0076 15.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KFM10357.1 - 2e-05 25.0 5.0 0.013 15.8 0.4 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KFM10357.1 - 2.5e-05 23.7 0.4 0.12 11.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KFM10357.1 - 0.00064 19.0 2.2 1.9 7.6 0.2 4.0 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KFM10357.1 - 0.00073 18.6 3.4 2.3 7.1 3.4 3.5 3 1 1 4 4 4 1 AAA ATPase domain MMR_HSR1 PF01926.18 KFM10357.1 - 0.00093 19.1 0.1 0.76 9.7 0.0 2.8 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KFM10357.1 - 0.0027 17.7 0.6 0.086 12.8 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KFM10357.1 - 0.0029 17.7 0.1 1.9 8.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KFM10357.1 - 0.0031 16.9 0.3 1 8.7 0.0 2.5 2 0 0 2 2 2 1 AAA-like domain AAA_33 PF13671.1 KFM10357.1 - 0.011 15.6 0.7 5 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 KFM10357.1 - 0.025 14.3 1.9 1.7 8.4 0.0 3.2 3 1 0 3 3 2 0 Dynamin family Rad17 PF03215.10 KFM10357.1 - 0.029 13.0 0.2 2.2 6.8 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein UPF0079 PF02367.12 KFM10357.1 - 0.057 13.0 3.0 3.7 7.1 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 KFM10357.1 - 0.094 13.5 1.3 4.8 8.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KFM10357.1 - 0.1 12.1 1.5 8.4 5.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 KFM10357.1 - 0.12 12.2 0.0 3.1 7.7 0.0 2.6 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 KFM10357.1 - 0.13 12.5 1.2 7.8 6.8 0.0 3.5 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 KFM10357.1 - 0.17 11.3 2.2 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.7 KFM10357.1 - 0.18 10.8 0.2 4.7 6.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.24 KFM10357.1 - 0.5 10.5 3.6 6.4 6.9 0.2 3.1 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KFM10357.1 - 0.78 9.5 3.2 7.4 6.4 0.0 2.7 3 0 0 3 3 2 0 Part of AAA domain PduV-EutP PF10662.4 KFM10357.1 - 0.99 8.8 5.0 0.77 9.2 0.0 3.1 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 KFM10358.1 - 3.8e-09 36.9 0.0 7.4e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KFM10358.1 - 0.00083 19.4 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 KFM10360.1 - 3.1e-07 29.7 9.0 3.8e-07 29.4 6.2 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.22 KFM10360.1 - 0.00027 21.2 0.4 0.00042 20.6 0.1 1.5 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 KFM10360.1 - 0.094 12.2 0.2 0.22 11.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.2 KFM10361.1 - 1.2e-07 31.1 1.1 1.4e-07 30.9 0.7 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.22 KFM10362.1 - 1.2e-59 200.5 0.0 5.8e-29 101.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 KFM10362.1 - 4e-38 131.3 56.3 3.8e-27 95.2 14.7 2.4 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 KFM10362.1 - 1e-18 68.3 0.0 7.2e-08 32.7 0.0 4.8 2 2 0 2 2 2 2 AAA domain DUF258 PF03193.11 KFM10362.1 - 1.5e-10 40.5 0.1 0.00037 19.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 KFM10362.1 - 4.9e-07 29.1 0.6 0.039 13.4 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.1 KFM10362.1 - 6.5e-07 28.7 0.2 0.28 10.2 0.0 4.4 5 0 0 5 5 5 2 AAA ATPase domain AAA_23 PF13476.1 KFM10362.1 - 1.1e-05 25.8 5.3 0.029 14.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 KFM10362.1 - 1.2e-05 25.3 0.0 0.099 12.6 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 KFM10362.1 - 7.5e-05 22.6 0.1 0.095 12.6 0.1 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KFM10362.1 - 0.00018 21.6 0.3 0.97 9.5 0.1 3.1 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KFM10362.1 - 0.00025 20.5 0.0 0.22 10.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 KFM10362.1 - 0.00031 20.6 0.0 0.018 14.8 0.0 2.8 2 1 0 2 2 2 1 Dynamin family NB-ARC PF00931.17 KFM10362.1 - 0.00074 18.4 2.8 1.9 7.2 0.0 3.3 3 0 0 3 3 3 1 NB-ARC domain AAA_10 PF12846.2 KFM10362.1 - 0.00085 18.8 0.4 0.51 9.7 0.0 2.7 2 1 0 2 2 2 1 AAA-like domain SMC_N PF02463.14 KFM10362.1 - 0.0011 18.2 0.2 2.8 7.1 0.0 3.8 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KFM10362.1 - 0.0012 19.6 0.0 1.2 9.9 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KFM10362.1 - 0.0016 18.3 0.2 1 9.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KFM10362.1 - 0.0026 17.2 0.9 0.29 10.5 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.12 KFM10362.1 - 0.003 16.9 0.2 1.7 8.0 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein MobB PF03205.9 KFM10362.1 - 0.0032 17.1 0.2 2.6 7.7 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KFM10362.1 - 0.0036 17.4 0.1 2.2 8.5 0.0 2.8 2 0 0 2 2 2 1 RNA helicase UPF0079 PF02367.12 KFM10362.1 - 0.0037 16.8 0.5 0.74 9.4 0.1 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_5 PF07728.9 KFM10362.1 - 0.004 16.8 0.7 1.2 8.8 0.0 3.9 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA PF00004.24 KFM10362.1 - 0.0047 17.1 0.0 2.8 8.1 0.0 3.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KFM10362.1 - 0.007 16.0 0.5 4.4 6.9 0.0 3.1 3 0 0 3 3 3 0 NACHT domain AAA_30 PF13604.1 KFM10362.1 - 0.0088 15.6 0.0 2.1 7.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 KFM10362.1 - 0.0099 15.7 0.0 3.3 7.7 0.0 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 KFM10362.1 - 0.014 15.1 0.1 1.2 8.9 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain Miro PF08477.8 KFM10362.1 - 0.019 15.4 0.3 9.4 6.7 0.0 3.3 3 0 0 3 3 2 0 Miro-like protein ATP-synt_ab PF00006.20 KFM10362.1 - 0.027 13.9 0.0 0.79 9.1 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain T2SE PF00437.15 KFM10362.1 - 0.062 12.1 0.1 4.8 5.9 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Mg_chelatase PF01078.16 KFM10362.1 - 0.092 11.8 0.2 8.5 5.4 0.0 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 KFM10362.1 - 0.13 12.2 0.3 16 5.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 KFM10362.1 - 0.25 10.0 0.7 0.63 8.7 0.1 1.8 2 0 0 2 2 2 0 ArgK protein Pkinase PF00069.20 KFM10363.1 - 2.9e-47 161.0 0.0 3.4e-47 160.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM10363.1 - 1.7e-33 115.8 0.0 2e-33 115.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM10363.1 - 6e-07 28.7 0.0 7.9e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KFM10363.1 - 0.0026 16.6 0.2 0.0038 16.0 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 KFM10363.1 - 0.0077 15.9 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFM10363.1 - 0.02 14.4 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase IRK PF01007.15 KFM10364.1 - 6.1e-141 469.0 2.5 7.6e-141 468.7 1.7 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 KFM10364.1 - 0.0022 17.6 6.0 0.0052 16.4 4.1 1.7 1 1 0 1 1 1 1 Ion channel IRK PF01007.15 KFM10365.1 - 7.6e-172 570.6 2.0 9.4e-172 570.3 1.4 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel IRK_N PF08466.5 KFM10365.1 - 1.6e-29 101.5 1.1 3.1e-29 100.6 0.8 1.5 1 0 0 1 1 1 1 Inward rectifier potassium channel N-terminal Ion_trans_2 PF07885.11 KFM10365.1 - 0.00082 19.0 6.7 0.0019 17.8 4.6 1.7 1 1 0 1 1 1 1 Ion channel Ion_trans PF00520.26 KFM10365.1 - 0.21 10.8 7.8 0.31 10.2 5.4 1.2 1 0 0 1 1 1 0 Ion transport protein zf-DHHC PF01529.15 KFM10365.1 - 0.68 9.3 6.7 1.3 8.4 4.7 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase HMG_box PF00505.14 KFM10366.1 - 3e-25 88.2 1.3 6.7e-25 87.1 0.9 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box Sox_N PF12444.3 KFM10366.1 - 2.9e-19 69.9 0.2 2.9e-19 69.9 0.1 3.6 3 2 0 3 3 3 1 Sox developmental protein N terminal HMG_box_2 PF09011.5 KFM10366.1 - 1.4e-10 41.3 1.0 1.4e-10 41.3 0.7 1.8 2 0 0 2 2 2 1 HMG-box domain Zip PF02535.17 KFM10367.1 - 3e-28 98.7 2.9 5.6e-28 97.8 2.0 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter 7tm_1 PF00001.16 KFM10368.1 - 3.7e-68 229.4 20.5 4.6e-68 229.1 14.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM10368.1 - 9.7e-17 60.9 21.3 1.2e-16 60.6 14.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 KFM10368.1 - 1e-11 44.4 8.5 1e-11 44.4 5.9 2.1 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.4 KFM10368.1 - 4.5e-08 32.5 19.8 4.5e-08 32.5 13.7 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Herpes_US9 PF06072.6 KFM10368.1 - 0.16 11.8 0.1 0.16 11.8 0.1 3.1 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 DUF1385 PF07136.6 KFM10368.1 - 3.7 6.5 10.9 0.055 12.5 0.6 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1385) FAM104 PF15434.1 KFM10370.1 - 2.7e-48 162.7 9.7 3.2e-48 162.4 6.7 1.1 1 0 0 1 1 1 1 Family 104 DUF4653 PF15546.1 KFM10370.1 - 0.032 13.5 2.6 0.037 13.3 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) DUF4638 PF15472.1 KFM10370.1 - 0.27 10.7 2.3 0.3 10.6 1.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) SR-25 PF10500.4 KFM10370.1 - 1.2 8.6 16.5 1.7 8.0 11.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein WRW PF10206.4 KFM10371.1 - 5.2e-23 81.0 0.0 6.3e-23 80.8 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f zf-CCCH PF00642.19 KFM10372.1 - 7.2e-17 60.6 29.9 5e-05 22.8 0.4 5.2 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ribosomal_L38e PF01781.13 KFM10373.1 - 8.5e-22 76.6 1.5 8.9e-22 76.6 1.0 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family Tweety PF04906.8 KFM10374.1 - 2.4e-93 312.7 5.3 3e-93 312.4 3.7 1.0 1 0 0 1 1 1 1 Tweety Tetraspannin PF00335.15 KFM10374.1 - 0.00072 18.8 5.7 0.0011 18.2 4.0 1.3 1 0 0 1 1 1 1 Tetraspanin family DUF4131 PF13567.1 KFM10374.1 - 0.088 12.2 8.5 0.16 11.3 5.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) SUR7 PF06687.7 KFM10374.1 - 0.25 10.8 5.0 0.41 10.1 3.5 1.3 1 0 0 1 1 1 0 SUR7/PalI family WD40 PF00400.27 KFM10375.1 - 3.9e-07 29.7 12.0 0.0068 16.2 0.0 5.5 6 0 0 6 6 6 2 WD domain, G-beta repeat GDPD PF03009.12 KFM10375.1 - 0.09 12.2 0.2 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family BACK PF07707.10 KFM10376.1 - 1.5e-16 60.0 0.1 2e-15 56.4 0.0 2.8 4 0 0 4 4 4 1 BTB And C-terminal Kelch BTB PF00651.26 KFM10376.1 - 3.5e-11 43.0 0.1 9.6e-11 41.6 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain 7tm_1 PF00001.16 KFM10377.1 - 1.3e-24 86.7 21.7 1.6e-24 86.4 15.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.4 KFM10377.1 - 2.7e-07 30.0 15.7 3.8e-06 26.2 2.4 2.3 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.4 KFM10377.1 - 0.33 10.0 19.4 0.007 15.5 6.9 2.5 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srbc PF10316.4 KFM10377.1 - 6.8 5.8 20.0 0.014 14.6 4.1 2.4 3 0 0 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srbc DUF3720 PF12517.3 KFM10378.1 - 1.3 9.8 4.9 3.8 8.2 0.8 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3720) PDE6_gamma PF04868.7 KFM10379.1 - 2.7e-30 104.0 6.8 3e-30 103.9 4.7 1.0 1 0 0 1 1 1 1 Retinal cGMP phosphodiesterase, gamma subunit NPL4 PF05021.10 KFM10380.1 - 3.8e-88 295.6 0.0 1.2e-87 293.9 0.0 1.9 1 1 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 KFM10380.1 - 1.9e-59 199.5 0.4 3.1e-59 198.8 0.3 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 KFM10380.1 - 3.4e-32 110.5 0.1 6.2e-32 109.7 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 FANCAA PF15146.1 KFM10381.1 - 4.2e-139 464.1 0.4 4.8e-139 464.0 0.3 1.0 1 0 0 1 1 1 1 Fanconi anemia-associated FANCAA PF15146.1 KFM10382.1 - 1.4e-50 172.5 0.5 1.5e-50 172.4 0.4 1.0 1 0 0 1 1 1 1 Fanconi anemia-associated Hemerythrin PF01814.18 KFM10382.1 - 0.19 11.8 1.3 4.9 7.3 0.1 2.0 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain Fascin PF06268.8 KFM10383.1 - 5.5e-60 200.3 0.0 7.5e-31 106.5 0.0 2.8 2 1 1 3 3 3 2 Fascin domain FRG1 PF06229.7 KFM10383.1 - 5.6e-10 38.9 0.0 1.5e-07 31.0 0.0 3.0 3 0 0 3 3 3 1 FRG1-like family DUF569 PF04601.8 KFM10383.1 - 0.00029 20.2 0.0 0.0089 15.4 0.0 2.5 2 1 1 3 3 3 1 Protein of unknown function (DUF569) RicinB_lectin_2 PF14200.1 KFM10383.1 - 0.014 15.7 0.0 0.22 11.9 0.0 2.2 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like DUF1214 PF06742.6 KFM10383.1 - 0.054 13.9 0.0 0.53 10.7 0.0 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF1214) FGF PF00167.13 KFM10383.1 - 0.094 12.4 0.0 0.25 11.1 0.0 1.8 1 0 0 1 1 1 0 Fibroblast growth factor Actin PF00022.14 KFM10384.1 - 9.9e-162 537.8 0.0 1.1e-161 537.6 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 KFM10384.1 - 0.08 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) MoCF_biosynth PF00994.19 KFM10386.1 - 2.3e-68 228.1 0.0 5e-38 129.7 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 KFM10386.1 - 6e-50 168.7 1.6 6.6e-50 168.6 0.2 1.7 2 0 0 2 2 2 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 KFM10386.1 - 4.1e-23 81.1 0.0 1.1e-22 79.7 0.0 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) DUF3699 PF12480.3 KFM10387.1 - 2.1e-20 72.0 0.7 3.9e-20 71.2 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3699) Guanylate_kin PF00625.16 KFM10388.1 - 5.1e-51 172.7 0.0 1.2e-50 171.4 0.0 1.7 1 0 0 1 1 1 1 Guanylate kinase L27_N PF09060.5 KFM10388.1 - 6.3e-25 86.7 2.4 1.7e-24 85.3 1.7 1.8 1 0 0 1 1 1 1 L27_N SH3_2 PF07653.12 KFM10388.1 - 1.4e-12 46.8 0.0 3.6e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain PDZ PF00595.19 KFM10388.1 - 3.8e-12 46.2 0.4 8.6e-12 45.0 0.3 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) L27 PF02828.11 KFM10388.1 - 5.6e-09 35.5 1.2 1.7e-08 34.0 0.9 1.7 1 0 0 1 1 1 1 L27 domain SH3_1 PF00018.23 KFM10388.1 - 9.5e-07 28.1 0.3 3.2e-06 26.4 0.2 2.0 1 1 0 1 1 1 1 SH3 domain PDZ_2 PF13180.1 KFM10388.1 - 1.9e-06 27.6 0.1 6.4e-06 25.9 0.1 1.9 1 0 0 1 1 1 1 PDZ domain SH3_9 PF14604.1 KFM10388.1 - 2.5e-05 23.7 0.1 5.8e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain MMR_HSR1 PF01926.18 KFM10388.1 - 0.057 13.3 0.0 0.85 9.5 0.0 3.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase ATP-synt_D PF01813.12 KFM10389.1 - 1.8e-66 223.4 8.6 2.2e-66 223.1 6.0 1.1 1 0 0 1 1 1 1 ATP synthase subunit D EIF_2_alpha PF07541.7 KFM10390.1 - 3.4e-37 126.6 0.0 6.6e-37 125.7 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 KFM10390.1 - 2.9e-15 56.1 0.7 7.4e-15 54.7 0.5 1.7 1 0 0 1 1 1 1 S1 RNA binding domain Herpes_BLRF2 PF05812.7 KFM10390.1 - 0.14 11.9 1.8 6.2 6.6 0.0 2.7 3 0 0 3 3 3 0 Herpesvirus BLRF2 protein PH PF00169.24 KFM10391.1 - 1.1e-30 105.9 0.0 3.7e-16 59.2 0.0 2.5 2 0 0 2 2 2 2 PH domain DEP PF00610.16 KFM10391.1 - 8.2e-17 60.7 0.0 2.1e-16 59.4 0.0 1.8 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_11 PF15413.1 KFM10391.1 - 2.8e-11 43.6 4.3 6.4e-05 23.1 0.0 3.8 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.1 KFM10391.1 - 7.4e-08 32.5 0.4 0.021 15.0 0.0 3.4 3 2 0 3 3 3 2 Pleckstrin homology domain PH_8 PF15409.1 KFM10391.1 - 0.0015 18.5 0.3 0.18 11.8 0.3 3.2 2 1 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.1 KFM10391.1 - 0.0065 16.5 0.0 0.36 10.8 0.0 2.7 3 0 0 3 3 3 1 Pleckstrin homology domain PH_4 PF15404.1 KFM10391.1 - 0.064 12.7 0.1 14 5.1 0.0 3.3 4 0 0 4 4 4 0 Pleckstrin homology domain Gal-bind_lectin PF00337.17 KFM10392.1 - 5.1e-31 106.7 0.0 5.6e-31 106.6 0.0 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin FYVE PF01363.16 KFM10394.1 - 1.3e-16 60.2 15.7 1.3e-16 60.2 10.9 2.1 2 0 0 2 2 2 1 FYVE zinc finger zf-DHHC PF01529.15 KFM10394.1 - 0.0048 16.3 0.0 0.0048 16.3 0.0 1.8 3 0 0 3 3 3 1 DHHC palmitoyltransferase MerR-DNA-bind PF09278.6 KFM10394.1 - 0.018 15.4 0.2 0.15 12.4 0.0 2.6 2 0 0 2 2 2 0 MerR, DNA binding A2L_zn_ribbon PF08792.5 KFM10394.1 - 0.084 12.3 0.0 0.084 12.3 0.0 3.0 3 1 0 3 3 3 0 A2L zinc ribbon domain FYVE_2 PF02318.11 KFM10394.1 - 0.81 9.6 15.1 0.16 11.9 7.7 1.9 2 0 0 2 2 2 0 FYVE-type zinc finger DUF2688 PF10892.3 KFM10394.1 - 0.99 9.1 4.9 2.4 7.9 3.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2688) TPR_2 PF07719.12 KFM10395.1 - 0.00066 19.3 0.4 0.0036 17.1 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat PBP_GOBP PF01395.17 KFM10395.1 - 0.054 13.1 1.8 0.11 12.0 0.4 2.2 2 1 0 2 2 2 0 PBP/GOBP family adh_short PF00106.20 KFM10396.1 - 3e-21 76.0 0.3 3e-21 76.0 0.2 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KFM10396.1 - 3.3e-08 33.3 0.2 5e-08 32.8 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFM10396.1 - 5.2e-05 22.7 0.1 8.2e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 KFM10396.1 - 7.9e-05 21.8 0.3 0.00011 21.3 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DUF1776 PF08643.5 KFM10396.1 - 0.018 14.1 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) V-SNARE_C PF12352.3 KFM10397.1 - 5.3e-20 71.2 7.8 5.3e-20 71.2 5.4 2.4 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.10 KFM10397.1 - 4.5e-13 49.1 5.6 4.5e-13 49.1 3.9 2.2 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.8 KFM10397.1 - 1.6e-05 24.4 1.7 1.6e-05 24.4 1.2 1.9 2 1 0 2 2 2 1 Sec20 SNARE PF05739.14 KFM10397.1 - 0.00065 19.3 0.8 0.00065 19.3 0.5 2.0 2 1 0 2 2 2 1 SNARE domain Laminin_II PF06009.7 KFM10397.1 - 0.0048 16.6 2.4 0.035 13.8 0.5 2.2 2 0 0 2 2 2 1 Laminin Domain II Fusion_gly PF00523.13 KFM10397.1 - 0.19 9.7 3.0 0.15 10.0 0.8 1.6 1 1 1 2 2 2 0 Fusion glycoprotein F0 DUF745 PF05335.8 KFM10397.1 - 1 8.8 4.5 8.8 5.7 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Snapin_Pallidin PF14712.1 KFM10397.1 - 1.1 9.6 8.7 0.63 10.3 0.3 2.5 2 1 0 2 2 2 0 Snapin/Pallidin Flagellin_C PF00700.16 KFM10397.1 - 1.4 9.1 5.8 0.44 10.7 0.4 2.3 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region Arginase PF00491.16 KFM10398.1 - 6.5e-72 242.1 0.0 7.9e-72 241.8 0.0 1.0 1 0 0 1 1 1 1 Arginase family PIG-H PF10181.4 KFM10399.1 - 1e-19 69.9 0.2 1.6e-19 69.2 0.1 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component zf-C4 PF00105.13 KFM10401.1 - 1.2e-28 99.1 15.8 2.2e-28 98.2 11.0 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 KFM10401.1 - 5.8e-26 90.8 0.1 1.2e-25 89.8 0.1 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor C6_DPF PF10170.4 KFM10402.1 - 4e-51 171.0 3.5 5e-51 170.7 2.4 1.1 1 0 0 1 1 1 1 Cysteine-rich domain PKD_channel PF08016.7 KFM10403.1 - 2.5e-109 365.5 12.6 5.1e-109 364.5 6.9 2.2 2 0 0 2 2 2 1 Polycystin cation channel REJ PF02010.10 KFM10403.1 - 2.3e-97 326.0 0.2 3.8e-97 325.3 0.2 1.3 1 0 0 1 1 1 1 REJ domain PLAT PF01477.18 KFM10403.1 - 1.2e-20 74.0 0.1 4.6e-20 72.0 0.0 2.1 1 0 0 1 1 1 1 PLAT/LH2 domain Ion_trans PF00520.26 KFM10403.1 - 7e-05 22.1 24.9 7e-05 22.1 17.3 2.9 3 0 0 3 3 3 1 Ion transport protein GPS PF01825.16 KFM10403.1 - 0.0072 16.4 1.5 0.02 14.9 1.0 1.8 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain TPR_14 PF13428.1 KFM10404.1 - 1.6e-06 28.2 0.2 1.5 9.6 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFM10404.1 - 0.00012 21.6 2.1 11 5.7 0.0 4.7 5 0 0 5 5 5 3 TPR repeat TPR_6 PF13174.1 KFM10404.1 - 0.0055 17.0 0.1 5.7 7.6 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFM10404.1 - 0.0092 15.8 7.1 7.6 6.7 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 KFM10404.1 - 0.023 14.6 1.9 5.9 6.9 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat RIH_assoc PF08454.6 KFM10404.1 - 0.093 12.3 0.0 0.26 10.8 0.0 1.7 1 0 0 1 1 1 0 RyR and IP3R Homology associated PARP PF00644.15 KFM10405.1 - 4.9e-42 143.7 0.5 1.1e-41 142.5 0.3 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.15 KFM10405.1 - 6.6e-08 31.8 1.6 6.6e-08 31.8 1.1 3.0 2 2 0 2 2 2 1 WWE domain zf-CCCH_2 PF14608.1 KFM10405.1 - 0.022 14.7 1.9 0.022 14.7 1.3 3.5 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type DUF3024 PF11225.3 KFM10405.1 - 0.11 12.3 2.6 0.96 9.3 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3024) Ets PF00178.17 KFM10406.1 - 7.6e-35 118.9 2.1 7.6e-35 118.9 1.5 1.9 2 0 0 2 2 2 1 Ets-domain SAM_PNT PF02198.11 KFM10406.1 - 7.2e-27 92.9 0.0 1.2e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain HSF_DNA-bind PF00447.12 KFM10406.1 - 0.018 15.1 0.0 0.041 14.0 0.0 1.6 1 0 0 1 1 1 0 HSF-type DNA-binding SAM_1 PF00536.25 KFM10406.1 - 0.048 13.8 0.6 0.14 12.3 0.4 1.8 1 1 0 1 1 1 0 SAM domain (Sterile alpha motif) Bcl-2 PF00452.14 KFM10407.1 - 0.00033 20.7 0.0 0.0012 18.9 0.0 2.0 1 1 1 2 2 2 1 Apoptosis regulator proteins, Bcl-2 family Ashwin PF15323.1 KFM10407.1 - 0.007 16.3 1.7 0.01 15.8 1.2 1.2 1 0 0 1 1 1 1 Developmental protein BID PF06393.6 KFM10407.1 - 0.021 14.1 0.0 0.04 13.2 0.0 1.5 1 0 0 1 1 1 0 BH3 interacting domain (BID) Orthopox_A47 PF06334.6 KFM10407.1 - 0.11 11.5 0.1 0.17 10.9 0.1 1.2 1 0 0 1 1 1 0 Orthopoxvirus A47 protein Ldl_recept_b PF00058.12 KFM10408.1 - 8.6e-158 512.4 49.0 9.3e-14 51.4 0.2 20.5 20 0 0 20 20 20 20 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.1 KFM10408.1 - 8.4e-39 131.4 68.1 3.1e-11 43.1 4.3 5.7 5 0 0 5 5 5 4 Coagulation Factor Xa inhibitory site Ldl_recept_a PF00057.13 KFM10408.1 - 1.1e-31 108.4 47.8 1e-11 44.4 6.2 3.7 3 0 0 3 3 3 3 Low-density lipoprotein receptor domain class A SGL PF08450.7 KFM10408.1 - 2.4e-17 63.1 16.5 0.049 12.9 0.0 11.8 7 3 3 11 11 11 5 SMP-30/Gluconolaconase/LRE-like region EGF PF00008.22 KFM10408.1 - 9.3e-07 28.6 53.0 0.011 15.7 1.8 6.1 5 1 0 5 5 5 4 EGF-like domain NHL PF01436.16 KFM10408.1 - 0.0002 21.1 0.0 4.8 7.3 0.0 6.1 7 0 0 7 7 7 1 NHL repeat cEGF PF12662.2 KFM10408.1 - 0.019 14.6 0.3 0.019 14.6 0.2 5.0 5 0 0 5 5 5 0 Complement Clr-like EGF-like Plasmid_Txe PF06769.8 KFM10408.1 - 0.19 11.5 2.7 34 4.3 0.1 4.2 4 0 0 4 4 4 0 Plasmid encoded toxin Txe MANEC PF07502.9 KFM10409.1 - 8.5e-23 80.1 1.0 1.4e-22 79.4 0.7 1.4 1 0 0 1 1 1 1 MANEC domain LOH1CR12 PF10158.4 KFM10410.1 - 1.1e-60 203.1 1.9 1.3e-60 202.8 1.3 1.1 1 0 0 1 1 1 1 Tumour suppressor protein DUF1664 PF07889.7 KFM10410.1 - 0.011 15.5 0.5 0.016 15.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ING PF12998.2 KFM10410.1 - 0.017 15.4 1.6 0.027 14.7 1.1 1.3 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding BLOC1_2 PF10046.4 KFM10410.1 - 0.025 14.7 0.9 0.049 13.7 0.6 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MRL1 PF13003.2 KFM10410.1 - 0.05 13.4 0.1 0.069 12.9 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L1 ERM PF00769.14 KFM10410.1 - 0.063 12.8 1.9 0.079 12.4 1.3 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DSPc PF00782.15 KFM10411.1 - 1.4e-42 144.4 0.0 2.6e-42 143.5 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.15 KFM10411.1 - 9e-16 58.2 0.0 1e-14 54.8 0.0 2.3 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.22 KFM10411.1 - 1.5e-05 24.4 0.0 3.8e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KFM10411.1 - 0.053 13.5 0.0 0.21 11.6 0.0 1.9 2 0 0 2 2 2 0 Inositol hexakisphosphate bZIP_2 PF07716.10 KFM10412.1 - 4.5e-08 32.7 7.3 6.8e-08 32.2 5.0 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KFM10412.1 - 2.9e-07 30.3 5.9 4.7e-07 29.6 4.1 1.4 1 0 0 1 1 1 1 bZIP transcription factor Abhydrolase_6 PF12697.2 KFM10413.1 - 7.5e-32 111.0 0.0 9e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFM10413.1 - 3.8e-18 65.8 0.0 2.4e-17 63.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFM10413.1 - 1.1e-11 44.6 0.0 2.2e-11 43.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KFM10413.1 - 9.5e-05 22.1 0.0 0.00018 21.3 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 KFM10413.1 - 0.00078 18.0 0.0 0.0024 16.3 0.0 1.7 2 0 0 2 2 2 1 Ndr family Abhydrolase_3 PF07859.8 KFM10413.1 - 0.065 12.8 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1071 PF06378.6 KFM10413.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) PAF-AH_p_II PF03403.8 KFM10413.1 - 0.12 10.6 0.0 0.23 9.7 0.0 1.4 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II OrgA_MxiK PF09482.5 KFM10414.1 - 0.12 12.0 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial type III secretion apparatus protein (OrgA_MxiK) Anoctamin PF04547.7 KFM10415.1 - 3.8e-143 477.4 23.0 4.5e-143 477.1 15.9 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Pkinase PF00069.20 KFM10416.1 - 2.4e-73 246.5 0.0 5e-73 245.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM10416.1 - 4.5e-42 143.9 0.0 6.7e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM10416.1 - 3.9e-10 39.1 0.0 2.3e-09 36.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFM10416.1 - 0.017 14.1 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KFM10416.1 - 0.069 12.4 0.0 0.78 9.0 0.0 2.4 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DUF563 PF04577.9 KFM10417.1 - 3.6e-22 79.2 0.1 7.6e-22 78.2 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF563) FAM198 PF15051.1 KFM10418.1 - 6.3e-132 439.2 0.0 7e-132 439.0 0.0 1.0 1 0 0 1 1 1 1 FAM198 protein DUF3018 PF11455.3 KFM10418.1 - 0.15 12.0 0.0 0.15 12.0 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3018) Ribosomal_L14e PF01929.12 KFM10419.1 - 1.9e-31 108.2 9.0 1.9e-31 108.2 6.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L14 KOW PF00467.24 KFM10419.1 - 0.0076 15.9 0.1 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 KOW motif DRY_EERY PF09750.4 KFM10419.1 - 3.9 7.6 10.2 7.9 6.6 7.0 1.5 1 1 0 1 1 1 0 Alternative splicing regulator AIG2_2 PF13772.1 KFM10420.1 - 5.6e-30 103.2 0.1 7.2e-30 102.9 0.1 1.1 1 0 0 1 1 1 1 AIG2-like family AIG2 PF06094.7 KFM10420.1 - 9.5e-05 22.8 0.0 0.00014 22.2 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family XG_FTase PF03254.8 KFM10420.1 - 0.065 11.7 0.1 0.17 10.3 0.0 1.5 1 1 1 2 2 2 0 Xyloglucan fucosyltransferase NACHT PF05729.7 KFM10421.1 - 4.7e-33 114.1 0.0 1.1e-32 112.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain LRR_6 PF13516.1 KFM10421.1 - 2.7e-19 67.0 2.4 0.099 12.7 0.0 8.9 8 0 0 8 8 8 6 Leucine Rich repeat CARD PF00619.16 KFM10421.1 - 3.7e-14 52.3 0.4 4.2e-13 48.9 0.1 2.8 3 0 0 3 3 3 1 Caspase recruitment domain LRR_4 PF12799.2 KFM10421.1 - 1.1e-07 31.2 0.7 0.51 10.0 0.0 4.9 3 1 0 4 4 4 2 Leucine Rich repeats (2 copies) AAA_16 PF13191.1 KFM10421.1 - 0.00032 20.7 0.0 0.0011 18.9 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain SpoU_sub_bind PF08032.7 KFM10421.1 - 0.0063 16.6 2.4 1.1 9.4 0.0 3.9 2 1 2 4 4 4 2 RNA 2'-O ribose methyltransferase substrate binding AAA_22 PF13401.1 KFM10421.1 - 0.074 13.1 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF4581 PF15167.1 KFM10422.1 - 7.2e-54 181.0 1.0 7.9e-54 180.9 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4581) Toxin_27 PF08099.6 KFM10422.1 - 0.093 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Scorpion calcine family EAF PF09816.4 KFM10423.1 - 4.5e-20 71.6 0.0 9.2e-20 70.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor TFIIIC_delta PF12657.2 KFM10423.1 - 0.0085 15.8 0.5 0.017 14.8 0.3 1.8 1 1 0 1 1 1 1 Transcription factor IIIC subunit delta N-term Macoilin PF09726.4 KFM10423.1 - 0.36 9.0 5.7 0.38 8.9 3.9 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF1117 PF06547.7 KFM10423.1 - 1.2 9.3 4.7 0.76 9.8 1.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1117) Methyltransf_12 PF08242.7 KFM10424.1 - 1.1e-17 64.3 0.1 8.2e-17 61.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFM10424.1 - 3.3e-15 56.1 0.0 5.6e-15 55.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFM10424.1 - 6e-13 48.6 0.0 8.4e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFM10424.1 - 2e-12 47.6 0.0 4.1e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFM10424.1 - 4.9e-11 42.9 0.1 1.8e-10 41.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFM10424.1 - 6.4e-08 32.8 0.0 1.7e-07 31.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFM10424.1 - 1.4e-07 31.5 0.0 2.4e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFM10424.1 - 4.1e-05 23.0 0.0 7.2e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 KFM10424.1 - 0.00015 21.1 0.0 0.00024 20.5 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.13 KFM10424.1 - 0.0002 20.5 0.0 0.00032 19.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FmrO PF07091.6 KFM10424.1 - 0.00089 18.3 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) CheR PF01739.13 KFM10424.1 - 0.0099 15.1 0.3 2.6 7.2 0.0 2.4 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain Methyltransf_4 PF02390.12 KFM10424.1 - 0.025 13.6 0.0 0.063 12.3 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_2 PF00891.13 KFM10424.1 - 0.079 12.1 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase SH3BP5 PF05276.9 KFM10425.1 - 1.5e-92 309.2 17.4 2.4e-92 308.5 12.1 1.3 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) DUF2884 PF11101.3 KFM10425.1 - 0.054 12.8 7.7 0.091 12.1 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) Med28 PF11594.3 KFM10425.1 - 0.62 10.3 10.2 2.2 8.5 1.4 2.9 1 1 1 2 2 2 0 Mediator complex subunit 28 Exonuc_VII_L PF02601.10 KFM10425.1 - 1.2 8.2 12.2 2 7.5 8.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit H-kinase_dim PF02895.9 KFM10425.1 - 7.3 7.0 7.0 1.3e+02 2.9 4.9 3.3 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain Calpain_III PF01067.17 KFM10426.1 - 8.9e-25 87.0 0.4 7.3e-17 61.3 0.0 2.5 2 1 0 2 2 2 2 Calpain large subunit, domain III Peptidase_C2 PF00648.16 KFM10427.1 - 8.5e-25 87.3 0.1 1.1e-21 77.1 0.0 2.2 2 0 0 2 2 2 2 Calpain family cysteine protease MIT PF04212.13 KFM10427.1 - 4.8e-17 61.6 6.2 1.5e-14 53.6 1.8 2.3 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain TPR_11 PF13414.1 KFM10427.1 - 0.021 14.4 0.5 0.021 14.4 0.3 2.1 2 0 0 2 2 2 0 TPR repeat TPR_12 PF13424.1 KFM10427.1 - 0.086 12.7 0.8 0.3 11.0 0.6 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 KFM10427.1 - 0.18 11.8 0.1 0.18 11.8 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFM10427.1 - 0.39 10.6 2.0 0.95 9.4 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat VSG_B PF13206.1 KFM10427.1 - 0.42 9.7 5.9 0.7 8.9 4.1 1.3 1 0 0 1 1 1 0 Trypanosomal VSG domain DUF1283 PF06932.6 KFM10427.1 - 0.5 10.4 2.1 0.55 10.2 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1283) PRCC PF10253.4 KFM10427.1 - 0.74 10.4 7.0 0.9 10.2 4.2 1.5 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting VWA PF00092.23 KFM10428.1 - 0.00022 21.0 0.0 0.00035 20.3 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Cadherin PF00028.12 KFM10430.1 - 9.9e-89 291.7 0.3 1.2e-19 70.3 0.0 6.4 6 0 0 6 6 6 6 Cadherin domain Cadherin_2 PF08266.7 KFM10430.1 - 4e-34 116.0 0.1 2.1e-30 104.1 0.0 4.4 5 0 0 5 5 5 2 Cadherin-like He_PIG PF05345.7 KFM10430.1 - 0.048 13.6 6.5 0.45 10.5 0.2 4.9 5 1 0 5 5 5 0 Putative Ig domain HTH_Tnp_1 PF01527.15 KFM10430.1 - 0.16 11.9 0.0 0.42 10.5 0.0 1.7 1 0 0 1 1 1 0 Transposase Big_3_4 PF13754.1 KFM10430.1 - 0.91 9.9 7.2 25 5.2 0.1 4.4 3 1 0 3 3 3 0 Bacterial Ig-like domain (group 3) Neur_chan_memb PF02932.11 KFM10432.1 - 1.8e-47 162.2 5.0 3.1e-41 141.8 1.0 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 KFM10432.1 - 1.6e-38 132.0 1.7 2.1e-38 131.6 1.2 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_LBD PF02931.18 KFM10433.1 - 5.5e-52 176.0 0.0 7.9e-52 175.5 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFM10433.1 - 3.7e-45 154.6 9.4 2.7e-36 125.6 4.6 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_memb PF02932.11 KFM10434.1 - 6.9e-53 179.9 2.8 1.4e-52 178.9 1.9 1.5 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 KFM10434.1 - 1.5e-44 151.7 0.0 2.1e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF4396 PF14342.1 KFM10434.1 - 0.71 9.9 8.6 0.88 9.6 0.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4396) Neur_chan_memb PF02932.11 KFM10435.1 - 1.4e-52 178.9 2.0 8e-52 176.4 1.4 1.9 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 KFM10435.1 - 4.8e-40 137.0 0.1 8.9e-40 136.1 0.0 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain HCaRG PF07258.9 KFM10436.1 - 2.6e-30 105.2 0.7 2.9e-30 105.1 0.5 1.0 1 0 0 1 1 1 1 HCaRG protein MgtE_N PF03448.12 KFM10436.1 - 0.015 15.5 0.7 0.12 12.6 0.1 2.2 2 0 0 2 2 2 0 MgtE intracellular N domain E1-E2_ATPase PF00122.15 KFM10437.1 - 5.9e-18 64.7 0.0 1.8e-17 63.1 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KFM10437.1 - 2.5e-16 60.7 0.0 2.1e-11 44.6 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFM10437.1 - 3.6e-15 56.6 0.0 4.1e-14 53.1 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFM10437.1 - 1.7e-09 37.4 0.0 5.6e-09 35.8 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFM10437.1 - 0.0061 16.1 0.1 0.0061 16.1 0.1 2.8 4 0 0 4 4 4 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KFM10437.1 - 0.023 14.9 0.0 0.065 13.4 0.0 1.8 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Trypsin PF00089.21 KFM10438.1 - 1.4e-63 214.3 0.1 3.1e-63 213.3 0.0 1.6 1 0 0 1 1 1 1 Trypsin Ldl_recept_a PF00057.13 KFM10438.1 - 1e-61 204.5 136.5 2.1e-10 40.2 8.2 9.3 8 1 0 8 8 8 7 Low-density lipoprotein receptor domain class A Fz PF01392.17 KFM10438.1 - 1.7e-51 173.4 19.8 1.3e-30 106.1 4.6 5.9 5 2 1 6 6 6 2 Fz domain SRCR_2 PF15494.1 KFM10438.1 - 2.7e-09 37.1 2.2 9.3e-09 35.4 0.9 2.6 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain zf-NF-X1 PF01422.12 KFM10439.1 - 4e-10 39.4 102.8 5e-05 23.1 8.5 18.6 18 0 0 18 18 18 12 NF-X1 type zinc finger Ion_trans PF00520.26 KFM10440.1 - 1e-19 70.5 4.3 1.6e-19 69.9 3.0 1.3 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.24 KFM10440.1 - 4.9e-17 61.5 0.0 8.4e-17 60.7 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HrpB7 PF09486.5 KFM10440.1 - 0.0053 16.6 0.2 0.23 11.3 0.1 2.2 2 0 0 2 2 2 1 Bacterial type III secretion protein (HrpB7) Ion_trans_2 PF07885.11 KFM10440.1 - 0.092 12.4 6.4 0.35 10.6 4.5 2.1 1 1 0 1 1 1 0 Ion channel Mg_trans_NIPA PF05653.9 KFM10441.1 - 1.2e-130 434.8 13.1 1.5e-130 434.5 9.1 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 KFM10441.1 - 8.6e-09 35.5 0.7 8.6e-09 35.5 0.5 3.3 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KFM10441.1 - 3.3e-08 33.6 5.0 3.3e-08 33.6 3.5 4.1 3 1 1 4 4 4 1 EamA-like transporter family Pkinase_Tyr PF07714.12 KFM10442.1 - 1e-95 319.7 0.1 1.3e-95 319.4 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM10442.1 - 6.7e-51 172.9 0.0 1.2e-50 172.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 KFM10442.1 - 1.2e-19 69.8 0.5 2.7e-19 68.7 0.4 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.23 KFM10442.1 - 1.4e-15 56.3 0.3 4.5e-15 54.7 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KFM10442.1 - 4.1e-08 32.6 0.1 9.7e-08 31.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFM10442.1 - 0.00036 19.9 0.0 0.00087 18.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH2_2 PF14633.1 KFM10442.1 - 0.0062 15.6 0.0 0.0094 15.0 0.0 1.3 1 0 0 1 1 1 1 SH2 domain DUF2509 PF10713.4 KFM10442.1 - 0.036 13.8 0.1 0.063 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2509) APH PF01636.18 KFM10442.1 - 0.085 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KFM10442.1 - 0.12 11.3 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase_Tyr PF07714.12 KFM10443.1 - 4.3e-94 314.3 0.1 6e-94 313.9 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM10443.1 - 1.7e-47 161.7 0.0 2.6e-47 161.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 KFM10443.1 - 4.9e-19 67.8 0.4 1.2e-18 66.6 0.1 1.8 2 0 0 2 2 2 1 SH2 domain SH3_1 PF00018.23 KFM10443.1 - 3.8e-14 51.7 0.5 1.6e-13 49.7 0.3 2.1 2 0 0 2 2 2 1 SH3 domain BTK PF00779.14 KFM10443.1 - 2.4e-13 49.4 1.3 4.6e-13 48.5 0.9 1.5 1 0 0 1 1 1 1 BTK motif PH PF00169.24 KFM10443.1 - 6.5e-08 32.7 0.2 0.00012 22.2 0.0 2.4 2 0 0 2 2 2 2 PH domain SH3_9 PF14604.1 KFM10443.1 - 6.6e-07 28.8 0.1 1.4e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFM10443.1 - 8.8e-07 28.3 0.1 2e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 KFM10443.1 - 0.0019 18.3 1.0 0.029 14.5 0.4 2.5 2 0 0 2 2 2 1 Bacterial SH3 domain Kinase-like PF14531.1 KFM10443.1 - 0.011 14.6 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like COBRA1 PF06209.8 KFM10444.1 - 5.6e-268 889.1 3.4 6.6e-268 888.9 2.4 1.1 1 0 0 1 1 1 1 Cofactor of BRCA1 (COBRA1) TFCD_C PF12612.3 KFM10444.1 - 0.029 13.7 0.1 0.084 12.2 0.0 1.9 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal GDA1_CD39 PF01150.12 KFM10445.1 - 3.3e-43 147.8 0.0 4e-43 147.5 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family zf-CSL PF05207.8 KFM10445.1 - 0.031 13.7 0.2 6 6.4 0.0 2.2 2 0 0 2 2 2 0 CSL zinc finger Tubulin PF00091.20 KFM10446.1 - 9.8e-70 234.7 0.0 1.5e-69 234.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFM10446.1 - 2.2e-50 169.9 0.1 3.6e-50 169.2 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KFM10446.1 - 0.00025 21.0 0.0 0.00059 19.8 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KFM10446.1 - 0.0072 15.8 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain DUF2475 PF10629.4 KFM10447.1 - 4e-09 36.5 0.2 1.8e-06 28.0 0.0 2.3 2 1 0 2 2 2 2 Protein of unknown function (DUF2475) SHIPPO-rpt PF07004.7 KFM10447.1 - 0.044 14.6 0.2 8.8 7.4 0.0 2.4 1 1 1 2 2 2 0 Sperm-tail PG-rich repeat Pkinase_Tyr PF07714.12 KFM10448.1 - 7.6e-85 284.1 0.0 1e-84 283.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM10448.1 - 1e-44 152.6 0.0 1.8e-44 151.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain TMEM154 PF15102.1 KFM10448.1 - 0.0024 17.5 0.8 0.0044 16.7 0.6 1.3 1 0 0 1 1 1 1 TMEM154 protein family F5_F8_type_C PF00754.20 KFM10448.1 - 0.0091 15.8 0.0 0.048 13.4 0.0 2.2 2 0 0 2 2 2 1 F5/8 type C domain Rifin_STEVOR PF02009.11 KFM10448.1 - 0.0094 15.6 0.1 0.016 14.8 0.1 1.3 1 0 0 1 1 1 1 Rifin/stevor family Mid2 PF04478.7 KFM10448.1 - 0.081 12.3 0.6 0.15 11.5 0.4 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Kinase-like PF14531.1 KFM10448.1 - 0.084 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like F5_F8_type_C PF00754.20 KFM10449.1 - 2.8e-14 53.0 0.0 3.3e-14 52.8 0.0 1.0 1 0 0 1 1 1 1 F5/8 type C domain Torsin PF06309.6 KFM10450.1 - 1.7e-14 53.7 0.1 5.4e-14 52.1 0.0 1.8 2 0 0 2 2 2 1 Torsin AAA_18 PF13238.1 KFM10450.1 - 0.0044 17.3 0.2 0.024 14.9 0.0 2.4 4 0 0 4 4 4 1 AAA domain AAA_22 PF13401.1 KFM10450.1 - 0.013 15.6 0.7 0.78 9.8 0.1 2.9 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 KFM10450.1 - 0.014 15.5 0.0 0.031 14.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.9 KFM10450.1 - 0.056 12.4 0.0 0.19 10.6 0.0 1.7 1 1 0 1 1 1 0 KAP family P-loop domain IstB_IS21 PF01695.12 KFM10450.1 - 0.078 12.3 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.1 KFM10450.1 - 0.088 12.7 0.0 0.41 10.6 0.0 2.0 1 1 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 KFM10450.1 - 0.097 13.4 0.0 0.37 11.6 0.0 2.1 1 1 0 1 1 1 0 AAA domain Cullin PF00888.17 KFM10451.1 - 3.2e-73 247.2 12.4 8.2e-71 239.2 2.3 3.4 2 1 1 3 3 3 3 Cullin family APC2 PF08672.6 KFM10451.1 - 1e-23 83.3 0.6 3.1e-23 81.7 0.4 1.9 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 Ribosomal_S2 PF00318.15 KFM10451.1 - 0.028 13.6 0.1 0.26 10.5 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein S2 Phostensin PF13914.1 KFM10452.1 - 8.6e-41 139.1 7.9 2.9e-40 137.4 0.9 2.4 2 0 0 2 2 2 2 Phostensin PP1-binding and SH3-binding region Saw1 PF11561.3 KFM10452.1 - 0.11 11.8 0.4 0.2 11.0 0.3 1.3 1 0 0 1 1 1 0 Single strand annealing-weakened 1 CENP-B_dimeris PF09026.5 KFM10452.1 - 5.6 7.2 9.1 8.2 6.7 2.9 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain IQ PF00612.22 KFM10453.1 - 0.0015 18.0 5.4 0.072 12.7 0.1 3.2 3 0 0 3 3 3 2 IQ calmodulin-binding motif cNMP_binding PF00027.24 KFM10454.1 - 4e-57 190.0 0.1 8.8e-18 63.9 0.0 3.4 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Patatin PF01734.17 KFM10454.1 - 2.7e-25 89.5 0.2 4.9e-25 88.6 0.1 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase MRP-L27 PF09809.4 KFM10455.1 - 2.5e-46 155.9 0.1 2.9e-46 155.7 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 WD40 PF00400.27 KFM10456.1 - 4.2e-09 35.9 10.5 1.9e-05 24.3 0.0 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat zf-MYND PF01753.13 KFM10457.1 - 4e-08 33.0 15.5 6.3e-08 32.3 10.7 1.4 1 0 0 1 1 1 1 MYND finger HNH_3 PF13392.1 KFM10457.1 - 6.3e-05 22.2 0.1 0.00012 21.3 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease zf-TAZ PF02135.11 KFM10457.1 - 3.7 7.6 11.6 5.8 6.9 8.0 1.2 1 0 0 1 1 1 0 TAZ zinc finger DUF2665 PF11654.3 KFM10458.1 - 0.081 12.5 0.0 0.085 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2665) SHIPPO-rpt PF07004.7 KFM10459.1 - 0.00013 22.6 0.5 0.00025 21.8 0.3 1.6 1 0 0 1 1 1 1 Sperm-tail PG-rich repeat Ribosomal_L11 PF00298.14 KFM10460.1 - 8e-12 45.1 0.1 1.1e-11 44.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.9 KFM10460.1 - 8e-07 28.4 0.0 1.3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain LRR_4 PF12799.2 KFM10461.1 - 7.4e-18 63.7 11.2 1.4e-08 34.1 0.2 5.5 4 2 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM10461.1 - 3.1e-17 62.0 16.2 1.4e-08 34.3 1.5 4.0 2 1 2 4 4 4 3 Leucine rich repeat zf-C3HC4_3 PF13920.1 KFM10461.1 - 6.2e-13 48.2 20.9 6.2e-13 48.2 14.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) LRR_1 PF00560.28 KFM10461.1 - 5.4e-11 40.9 7.5 1.1 9.6 0.0 6.9 6 0 0 6 6 6 3 Leucine Rich Repeat SAM_1 PF00536.25 KFM10461.1 - 4.4e-09 36.3 1.2 7e-08 32.5 0.0 3.1 3 0 0 3 3 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFM10461.1 - 3.4e-07 30.0 2.8 3.3e-06 26.8 0.0 3.6 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) LRR_7 PF13504.1 KFM10461.1 - 9.3e-05 22.0 15.8 5.3 7.6 0.0 7.2 7 0 0 7 7 6 2 Leucine rich repeat Prok-RING_4 PF14447.1 KFM10461.1 - 0.0013 18.2 11.3 0.0028 17.1 7.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.1 KFM10461.1 - 0.006 16.5 23.9 0.006 16.5 16.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) HEAT_2 PF13646.1 KFM10461.1 - 0.0095 16.1 0.5 0.045 14.0 0.4 2.2 1 0 0 1 1 1 1 HEAT repeats DUF2322 PF10084.4 KFM10461.1 - 0.044 13.5 0.4 4.9 6.9 0.0 3.0 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2322) zf-RING_2 PF13639.1 KFM10461.1 - 0.53 10.1 23.3 1.3 8.9 16.1 1.7 1 0 0 1 1 1 0 Ring finger domain LRR_6 PF13516.1 KFM10461.1 - 1.7 8.9 9.2 35 4.9 0.1 4.9 6 0 0 6 6 4 0 Leucine Rich repeat zf-RING_5 PF14634.1 KFM10461.1 - 3.6 7.4 26.7 0.66 9.7 15.7 1.9 2 0 0 2 2 2 0 zinc-RING finger domain Ctr PF04145.10 KFM10462.1 - 1.2e-47 161.5 5.3 1.5e-47 161.3 3.7 1.1 1 0 0 1 1 1 1 Ctr copper transporter family WD40 PF00400.27 KFM10463.1 - 3.1e-58 191.6 18.1 7.2e-11 41.5 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 KFM10463.1 - 3e-15 55.1 0.8 8.9e-15 53.6 0.5 1.9 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Nup160 PF11715.3 KFM10463.1 - 0.021 12.9 0.3 1.9 6.5 0.0 3.4 3 1 1 4 4 4 0 Nucleoporin Nup120/160 WD40 PF00400.27 KFM10464.1 - 7.4e-33 111.2 21.4 1.2e-06 28.1 0.1 7.6 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 KFM10464.1 - 3.2e-05 22.2 1.5 0.53 8.3 0.0 3.6 2 1 1 3 3 3 3 Nucleoporin Nup120/160 HAD_2 PF13419.1 KFM10465.1 - 7.4e-26 91.4 0.0 9.6e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFM10465.1 - 1.4e-09 38.6 0.0 2.2e-09 38.0 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFM10465.1 - 2.1e-09 36.9 0.0 3.9e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 KFM10465.1 - 0.0064 16.3 0.0 0.016 15.0 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase ALAD PF00490.16 KFM10466.1 - 5.4e-99 331.1 0.0 6.5e-99 330.8 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase CBFD_NFYB_HMF PF00808.18 KFM10467.1 - 1.6e-07 31.2 0.0 2.9e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KFM10467.1 - 0.0069 16.4 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 SpoU_methylase PF00588.14 KFM10467.1 - 0.009 15.8 0.1 0.011 15.5 0.0 1.1 1 0 0 1 1 1 1 SpoU rRNA Methylase family DUF1510 PF07423.6 KFM10467.1 - 0.013 14.8 10.1 0.012 14.9 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) BUD22 PF09073.5 KFM10467.1 - 0.043 12.8 14.0 0.044 12.8 9.7 1.1 1 0 0 1 1 1 0 BUD22 Pox_Ag35 PF03286.9 KFM10467.1 - 0.061 12.8 11.0 0.068 12.6 7.6 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Daxx PF03344.10 KFM10467.1 - 0.07 11.6 13.1 0.064 11.7 9.1 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 KFM10467.1 - 0.16 10.0 11.4 0.16 10.0 7.9 1.0 1 0 0 1 1 1 0 CDC45-like protein U79_P34 PF03064.11 KFM10467.1 - 0.28 10.6 12.3 0.31 10.5 8.5 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 FLO_LFY PF01698.11 KFM10467.1 - 0.43 9.3 7.1 0.46 9.2 4.9 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF2956 PF11169.3 KFM10467.1 - 0.53 10.2 8.5 0.79 9.7 5.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) TraH_2 PF06871.6 KFM10467.1 - 0.54 9.6 5.0 0.64 9.4 3.5 1.1 1 0 0 1 1 1 0 TraH_2 Peptidase_S49_N PF08496.5 KFM10467.1 - 0.56 9.9 3.7 0.66 9.7 2.6 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Vfa1 PF08432.5 KFM10467.1 - 0.7 9.8 14.3 0.82 9.6 9.9 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 GAGA_bind PF06217.7 KFM10467.1 - 0.72 9.7 5.7 0.77 9.6 4.0 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family CobT PF06213.7 KFM10467.1 - 1.5 7.9 16.1 1.6 7.8 11.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DDHD PF02862.12 KFM10467.1 - 1.5 8.5 5.4 1.4 8.6 3.7 1.1 1 0 0 1 1 1 0 DDHD domain Ycf1 PF05758.7 KFM10467.1 - 1.7 6.2 6.4 1.6 6.3 4.4 1.0 1 0 0 1 1 1 0 Ycf1 PBP_sp32 PF07222.7 KFM10467.1 - 3 6.9 8.7 3.2 6.8 6.0 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Myc_N PF01056.13 KFM10467.1 - 3.1 6.8 10.3 4 6.5 7.1 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF4337 PF14235.1 KFM10467.1 - 7.7 6.3 6.0 9.3 6.0 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Cytomega_UL84 PF06284.6 KFM10467.1 - 8.2 4.7 7.6 10 4.4 5.2 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein C2 PF00168.25 KFM10468.1 - 3.2e-17 62.1 0.0 4.4e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 C2 domain CEP76-C2 PF15627.1 KFM10468.1 - 0.0015 18.0 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 CEP76 C2 domain Pep_M12B_propep PF01562.14 KFM10468.1 - 0.036 13.8 0.0 0.057 13.2 0.0 1.4 1 1 0 1 1 1 0 Reprolysin family propeptide RGS PF00615.14 KFM10469.1 - 4.4e-37 126.7 3.7 5e-37 126.6 2.6 1.0 1 0 0 1 1 1 1 Regulator of G protein signaling domain zf-H2C2_2 PF13465.1 KFM10470.1 - 2.5e-13 49.5 18.5 9.5e-08 31.9 0.8 2.4 3 0 0 3 3 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM10470.1 - 6.3e-10 38.6 14.5 8.8e-06 25.7 1.7 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KFM10470.1 - 1e-09 38.1 19.9 1.8e-06 27.9 1.9 2.5 3 0 0 3 3 2 2 Zinc finger, C2H2 type zf-C2HC_2 PF13913.1 KFM10470.1 - 1.9e-05 24.1 4.9 0.00018 21.0 0.5 2.3 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 KFM10470.1 - 0.00076 19.5 0.4 0.00076 19.5 0.3 3.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding C1_1 PF00130.17 KFM10470.1 - 0.00095 18.8 1.6 0.0027 17.4 1.1 1.7 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-CHCC PF10276.4 KFM10470.1 - 0.0014 18.3 1.1 1.1 9.1 0.0 2.1 2 0 0 2 2 2 2 Zinc-finger domain Zn-ribbon_8 PF09723.5 KFM10470.1 - 0.0016 18.3 4.6 0.37 10.7 0.2 2.1 2 0 0 2 2 2 2 Zinc ribbon domain FdhE PF04216.7 KFM10470.1 - 0.0018 18.0 1.3 0.002 17.9 0.9 1.0 1 0 0 1 1 1 1 Protein involved in formate dehydrogenase formation zf-C2H2_6 PF13912.1 KFM10470.1 - 0.002 17.9 12.1 0.019 14.8 0.1 2.6 3 0 0 3 3 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 KFM10470.1 - 0.0035 17.4 8.5 0.032 14.3 0.8 2.2 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 KFM10470.1 - 0.0067 16.5 8.4 0.33 11.0 0.5 2.1 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) PyrI_C PF02748.10 KFM10470.1 - 0.0088 15.4 0.8 0.13 11.7 0.1 2.1 2 0 0 2 2 2 1 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-AN1 PF01428.11 KFM10470.1 - 0.011 15.6 1.8 2 8.3 0.0 2.3 2 0 0 2 2 2 0 AN1-like Zinc finger zf-met PF12874.2 KFM10470.1 - 0.013 15.6 1.7 0.013 15.6 1.2 2.9 2 1 1 3 3 3 0 Zinc-finger of C2H2 type TerY-C PF15616.1 KFM10470.1 - 0.021 14.7 0.3 0.022 14.6 0.2 1.1 1 0 0 1 1 1 0 TerY-C metal binding domain XPA_N PF01286.13 KFM10470.1 - 0.035 13.7 0.1 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 XPA protein N-terminal YyzF PF14116.1 KFM10470.1 - 0.036 14.0 1.6 4.4 7.3 0.2 2.2 2 0 0 2 2 2 0 YyzF-like protein zf-RING_3 PF14369.1 KFM10470.1 - 0.038 13.9 0.9 0.6 10.1 0.1 2.1 2 0 0 2 2 2 0 zinc-finger DUF2321 PF10083.4 KFM10470.1 - 0.1 12.0 0.5 0.11 11.9 0.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) Zn_Tnp_IS1595 PF12760.2 KFM10470.1 - 0.11 12.3 4.0 0.16 11.8 2.8 1.4 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-BED PF02892.10 KFM10470.1 - 0.12 12.1 8.5 0.26 11.0 0.8 2.4 1 1 1 2 2 2 0 BED zinc finger zinc-ribbons_6 PF07191.7 KFM10470.1 - 0.16 11.8 3.9 1.2 8.9 2.2 2.2 1 1 1 2 2 2 0 zinc-ribbons DUF2688 PF10892.3 KFM10470.1 - 0.17 11.5 0.6 1.5 8.5 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) NADH-G_4Fe-4S_3 PF10588.4 KFM10470.1 - 0.17 11.1 3.4 3 7.1 0.6 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region GAGA PF09237.6 KFM10470.1 - 0.37 10.4 4.7 0.42 10.2 1.0 2.0 1 1 1 2 2 2 0 GAGA factor DUF2256 PF10013.4 KFM10470.1 - 0.55 10.0 3.2 4.4 7.1 0.5 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-ribbon_3 PF13248.1 KFM10470.1 - 0.57 9.4 4.2 0.87 8.8 0.3 2.1 2 0 0 2 2 2 0 zinc-ribbon domain FYVE PF01363.16 KFM10470.1 - 0.7 9.8 6.1 2.7 7.9 3.7 1.9 1 1 1 2 2 2 0 FYVE zinc finger zf-C4_ClpX PF06689.8 KFM10470.1 - 0.83 9.2 3.4 0.58 9.7 0.2 2.0 2 0 0 2 2 2 0 ClpX C4-type zinc finger zinc_ribbon_5 PF13719.1 KFM10470.1 - 1.5 8.4 6.8 2.8 7.6 0.8 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Cys_rich_CPXG PF14255.1 KFM10470.1 - 1.5 8.6 4.2 8.8 6.2 0.3 2.3 2 0 0 2 2 2 0 Cysteine-rich CPXCG zinc_ribbon_4 PF13717.1 KFM10470.1 - 1.7 8.4 6.0 2.1 8.1 0.5 2.2 2 0 0 2 2 2 0 zinc-ribbon domain C1_4 PF07975.7 KFM10470.1 - 2.1 8.4 5.6 8.5 6.4 3.1 2.0 1 1 1 2 2 2 0 TFIIH C1-like domain Ribosomal_L37ae PF01780.14 KFM10470.1 - 2.2 8.1 4.0 13 5.6 2.8 2.0 1 1 0 1 1 1 0 Ribosomal L37ae protein family zf-ISL3 PF14690.1 KFM10470.1 - 4.1 7.5 10.0 9.4 6.3 2.2 2.5 1 1 2 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Sugar_tr PF00083.19 KFM10471.1 - 1.1e-157 525.2 25.9 1.4e-157 524.9 18.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFM10471.1 - 3.2e-20 72.1 31.6 1.6e-18 66.5 14.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFM10471.1 - 6.5e-05 21.5 33.7 0.00068 18.1 4.6 3.5 2 1 0 3 3 3 2 MFS/sugar transport protein 60KD_IMP PF02096.15 KFM10471.1 - 0.003 17.2 1.2 0.003 17.2 0.8 1.7 2 0 0 2 2 2 1 60Kd inner membrane protein Syndecan PF01034.15 KFM10471.1 - 0.2 11.3 2.7 9.5 5.9 0.6 3.1 2 0 0 2 2 2 0 Syndecan domain ESSS PF10183.4 KFM10471.1 - 1 9.8 2.5 4.6 7.6 0.4 2.7 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) TPR_12 PF13424.1 KFM10472.1 - 2.8e-15 56.0 7.4 3.7e-05 23.5 0.2 3.4 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 KFM10472.1 - 1.2e-07 31.2 4.1 0.073 12.7 0.0 4.3 4 0 0 4 4 4 3 TPR repeat TPR_2 PF07719.12 KFM10472.1 - 0.00043 19.9 8.0 7.6 6.7 0.6 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFM10472.1 - 0.0066 17.0 6.3 5 7.9 0.1 4.3 3 1 0 4 4 4 1 Tetratricopeptide repeat RPN7 PF10602.4 KFM10472.1 - 0.076 12.3 0.0 6 6.2 0.0 2.3 2 0 0 2 2 2 0 26S proteasome subunit RPN7 TPR_1 PF00515.23 KFM10472.1 - 0.26 10.9 6.4 12 5.7 0.3 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 KFM10472.1 - 0.53 10.3 6.9 30 4.7 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 KFM10472.1 - 0.71 10.4 5.2 58 4.4 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat IncA PF04156.9 KFM10473.1 - 0.59 9.6 105.1 0.092 12.3 24.6 4.7 1 1 2 3 3 3 0 IncA protein DUF4496 PF14908.1 KFM10474.1 - 0.0045 16.8 0.1 0.0051 16.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4496) NUP50 PF08911.6 KFM10475.1 - 6.7e-26 90.4 0.9 6.7e-26 90.4 0.6 2.8 2 0 0 2 2 2 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.13 KFM10475.1 - 1.1e-10 41.6 0.0 1.9e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain DUF2045 PF09741.4 KFM10476.1 - 1.2e-118 394.4 3.0 1.5e-118 394.1 2.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2045) SIR2_2 PF13289.1 KFM10477.1 - 2.3e-17 63.2 0.0 4e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 SIR2-like domain RIB43A PF05914.7 KFM10478.1 - 2.9e-109 365.1 53.2 3.3e-109 365.0 36.9 1.0 1 0 0 1 1 1 1 RIB43A UBA_3 PF09288.5 KFM10479.1 - 0.0099 15.4 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain BMF PF15185.1 KFM10480.1 - 1.1e-79 266.8 0.6 1.3e-79 266.6 0.4 1.1 1 0 0 1 1 1 1 Bcl-2-modifying factor, apoptosis SRP14 PF02290.10 KFM10481.1 - 8.6e-32 108.9 0.1 8.6e-32 108.9 0.1 1.4 2 0 0 2 2 2 1 Signal recognition particle 14kD protein 7tm_1 PF00001.16 KFM10482.1 - 1.3e-30 106.4 28.8 1.6e-30 106.1 20.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4083 PF13314.1 KFM10482.1 - 0.15 11.9 3.5 0.63 9.9 2.4 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) FSIP1 PF15554.1 KFM10483.1 - 2.5e-17 62.8 4.1 3e-17 62.5 2.8 1.1 1 0 0 1 1 1 1 FSIP1 family TSP_C PF05735.7 KFM10485.1 - 4e-75 251.8 1.9 6e-75 251.2 1.3 1.3 1 0 0 1 1 1 1 Thrombospondin C-terminal region TSP_3 PF02412.13 KFM10485.1 - 2.7e-49 164.3 156.7 2.1e-12 46.2 9.4 10.5 10 1 1 11 11 11 9 Thrombospondin type 3 repeat TSP_1 PF00090.14 KFM10485.1 - 6.8e-39 131.7 46.8 4.7e-16 58.6 5.9 4.9 6 0 0 6 6 6 3 Thrombospondin type 1 domain VWC PF00093.13 KFM10485.1 - 9.3e-13 48.0 17.8 9.3e-13 48.0 12.4 6.6 4 3 1 5 5 5 1 von Willebrand factor type C domain cEGF PF12662.2 KFM10485.1 - 1.5e-09 37.3 15.0 1.7e-07 30.7 0.6 4.9 3 0 0 3 3 3 2 Complement Clr-like EGF-like EGF_3 PF12947.2 KFM10485.1 - 9.4e-07 28.6 10.4 9.4e-07 28.6 7.2 6.2 6 0 0 6 6 6 2 EGF domain EGF_CA PF07645.10 KFM10485.1 - 1.2e-05 25.1 1.6 1.2e-05 25.1 1.1 5.9 5 0 0 5 5 5 3 Calcium-binding EGF domain EGF PF00008.22 KFM10485.1 - 0.00043 20.1 9.5 0.00043 20.1 6.6 5.7 4 0 0 4 4 4 2 EGF-like domain Laminin_G_2 PF02210.19 KFM10485.1 - 0.034 14.1 0.4 0.081 12.9 0.2 1.6 1 1 0 1 1 1 0 Laminin G domain Katanin_con80 PF13925.1 KFM10486.1 - 3.6e-44 150.3 0.1 5.9e-44 149.6 0.1 1.3 1 0 0 1 1 1 1 con80 domain of Katanin DUF2012 PF09430.5 KFM10487.1 - 4e-30 104.1 0.1 5.3e-30 103.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.1 KFM10487.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain 7tm_1 PF00001.16 KFM10488.1 - 3.4e-87 291.8 5.7 4.4e-87 291.4 4.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 KFM10488.1 - 2.3e-08 33.5 8.1 2.3e-08 33.5 5.6 1.9 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx PCI PF01399.22 KFM10490.1 - 2.5e-18 66.2 2.1 1e-17 64.3 0.0 2.7 3 0 0 3 3 3 1 PCI domain TPR_12 PF13424.1 KFM10490.1 - 0.0032 17.3 4.3 0.22 11.5 1.6 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFM10490.1 - 0.012 15.3 1.5 1.3 8.9 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat RPN7 PF10602.4 KFM10490.1 - 0.018 14.3 0.9 0.034 13.5 0.6 1.4 1 0 0 1 1 1 0 26S proteasome subunit RPN7 TPR_14 PF13428.1 KFM10490.1 - 0.091 13.4 6.7 0.15 12.7 0.1 4.0 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF972 PF06156.8 KFM10490.1 - 0.93 9.8 6.9 5.7 7.3 0.1 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF972) TPR_19 PF14559.1 KFM10490.1 - 1.5 9.2 7.6 0.38 11.1 1.1 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TCR PF03638.10 KFM10491.1 - 3.9e-24 84.2 55.7 6.7e-13 48.2 15.3 2.6 3 0 0 3 3 3 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain Tnp_P_element PF12017.3 KFM10492.1 - 3.8e-07 29.5 0.0 2.9e-06 26.6 0.0 2.0 1 1 0 1 1 1 1 Transposase protein DUF3735 PF12537.3 KFM10492.1 - 0.067 13.2 0.1 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3735) WD40 PF00400.27 KFM10493.1 - 7.1e-16 57.4 3.7 0.0038 17.0 0.0 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat Sec16_C PF12931.2 KFM10493.1 - 2e-06 27.8 1.0 4.7e-06 26.5 0.7 1.6 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 SRA1 PF07304.6 KFM10493.1 - 0.00024 20.8 0.0 0.00073 19.2 0.0 1.8 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.10 KFM10493.1 - 0.013 15.3 0.1 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 Prp18 domain FA_desaturase PF00487.19 KFM10494.1 - 1.1e-18 67.6 11.9 1.6e-18 67.0 8.2 1.2 1 0 0 1 1 1 1 Fatty acid desaturase UbiA PF01040.13 KFM10494.1 - 0.015 14.5 2.3 1.2 8.3 0.1 2.3 2 0 0 2 2 2 0 UbiA prenyltransferase family PetL PF05115.9 KFM10494.1 - 2.6 8.0 6.3 0.78 9.7 1.8 2.2 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit VI (PetL) Frag1 PF10277.4 KFM10495.1 - 1.3e-44 152.2 7.4 1.5e-44 152.0 5.1 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF998 PF06197.8 KFM10495.1 - 0.00026 20.3 5.9 0.00026 20.3 4.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF998) DUF202 PF02656.10 KFM10495.1 - 0.91 9.7 5.6 6.8 6.9 0.9 3.1 2 2 0 2 2 2 0 Domain of unknown function (DUF202) O-antigen_lig PF13425.1 KFM10495.1 - 1.3 8.9 8.2 5.5 6.9 0.1 2.6 3 0 0 3 3 3 0 O-antigen ligase like membrane protein HAD_2 PF13419.1 KFM10496.1 - 5.7e-20 72.2 0.0 7.3e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase RRM_1 PF00076.17 KFM10497.1 - 8.5e-40 134.2 0.1 9.2e-19 66.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM10497.1 - 4.7e-31 106.5 0.0 1.5e-14 53.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM10497.1 - 8.1e-12 44.8 0.0 8.4e-05 22.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFM10497.1 - 2.2e-05 24.2 0.2 0.012 15.4 0.0 2.7 2 2 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 KFM10497.1 - 0.00033 20.3 0.0 0.022 14.5 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif NID PF07292.8 KFM10497.1 - 0.019 15.0 0.8 1.7 8.7 0.0 3.1 4 0 0 4 4 4 0 Nmi/IFP 35 domain (NID) RRM_1 PF00076.17 KFM10498.1 - 3e-42 142.0 0.7 8.9e-21 73.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM10498.1 - 8.6e-33 112.1 0.1 3.1e-15 55.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM10498.1 - 7.1e-12 44.9 0.3 7.8e-05 22.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFM10498.1 - 6.3e-07 29.1 0.7 0.035 13.9 0.0 2.7 2 1 0 2 2 2 2 RNA binding motif NID PF07292.8 KFM10498.1 - 9.4e-05 22.3 1.4 0.022 14.7 0.0 2.5 2 1 0 2 2 2 2 Nmi/IFP 35 domain (NID) Nup35_RRM_2 PF14605.1 KFM10498.1 - 0.004 16.9 0.0 0.18 11.5 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DnaJ PF00226.26 KFM10499.1 - 1.3e-21 76.0 0.2 3e-21 74.9 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain RRM_5 PF13893.1 KFM10499.1 - 3.1e-08 33.3 0.0 1e-07 31.6 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFM10499.1 - 2.8e-05 23.6 0.0 7e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM10499.1 - 8.4e-05 22.4 0.0 0.00024 20.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FAD-SLDH PF12318.3 KFM10499.1 - 0.33 10.6 4.6 0.1 12.2 1.1 1.7 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase BORG_CEP PF14957.1 KFM10500.1 - 4.1e-09 37.4 0.8 7.7e-09 36.5 0.6 1.7 1 1 0 1 1 1 1 Cdc42 effector GFRP PF06399.8 KFM10501.1 - 1.1e-38 130.7 0.0 1.1e-38 130.6 0.0 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I feedback regulatory protein (GFRP) TPR_11 PF13414.1 KFM10502.1 - 0.00019 20.9 0.2 0.56 9.8 0.0 3.5 3 0 0 3 3 3 2 TPR repeat TPR_17 PF13431.1 KFM10502.1 - 0.001 19.0 0.9 0.0072 16.4 0.0 2.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFM10502.1 - 0.003 18.1 0.0 1.6 9.4 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFM10502.1 - 0.011 15.4 0.1 0.45 10.4 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Orbi_VP5 PF00901.12 KFM10502.1 - 0.074 11.2 0.1 0.12 10.6 0.0 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 SPX PF03105.14 KFM10502.1 - 5.9 6.5 8.2 14 5.3 5.6 1.7 1 1 0 1 1 1 0 SPX domain Rad51 PF08423.6 KFM10503.1 - 2.8e-142 472.0 0.1 3.5e-142 471.7 0.1 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KFM10503.1 - 1.3e-14 54.1 0.0 1.8e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 KFM10503.1 - 9.9e-13 48.0 2.0 1.2e-12 47.8 0.5 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain RecA PF00154.16 KFM10503.1 - 2.1e-08 33.5 0.1 3.2e-08 33.0 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 KFM10503.1 - 8.7e-06 25.0 1.6 2.7e-05 23.4 0.4 2.2 2 1 0 2 2 2 1 KaiC AAA_22 PF13401.1 KFM10503.1 - 0.00063 19.8 0.0 0.0013 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain HHH PF00633.18 KFM10503.1 - 0.0065 16.1 0.1 0.017 14.8 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HhH-GPD PF00730.20 KFM10503.1 - 0.026 14.7 0.0 0.15 12.3 0.0 2.0 1 1 1 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein Hemerythrin PF01814.18 KFM10504.1 - 0.025 14.7 2.8 0.15 12.2 0.2 2.6 2 1 0 2 2 2 0 Hemerythrin HHE cation binding domain EcsC PF12787.2 KFM10504.1 - 0.078 12.3 0.4 0.14 11.5 0.0 1.6 2 0 0 2 2 2 0 EcsC protein family Phe_tRNA-synt_N PF02912.13 KFM10504.1 - 0.31 10.7 0.0 0.31 10.7 0.0 2.3 3 0 0 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain FlgN PF05130.7 KFM10504.1 - 0.56 10.4 14.2 19 5.5 8.8 2.7 2 1 1 3 3 3 0 FlgN protein CAP_N PF01213.14 KFM10504.1 - 3.8 6.7 6.6 3.3 6.9 3.6 1.6 1 1 1 2 2 2 0 Adenylate cyclase associated (CAP) N terminal IncA PF04156.9 KFM10504.1 - 9.5 5.7 20.2 15 5.1 5.8 2.5 1 1 1 2 2 2 0 IncA protein PseudoU_synth_2 PF00849.17 KFM10506.1 - 5.4e-32 110.8 1.2 9.8e-32 110.0 0.2 1.8 2 0 0 2 2 2 1 RNA pseudouridylate synthase PCMT PF01135.14 KFM10507.1 - 9.9e-81 270.2 0.0 1.2e-80 270.0 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 KFM10507.1 - 1.5e-08 35.1 0.0 2.8e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFM10507.1 - 3.4e-07 29.9 0.0 4.7e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFM10507.1 - 5e-05 23.7 0.0 0.00011 22.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFM10507.1 - 0.00041 19.5 0.0 0.00058 19.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family GCD14 PF08704.5 KFM10507.1 - 0.0024 17.4 0.0 0.0028 17.2 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_25 PF13649.1 KFM10507.1 - 0.0047 17.2 0.0 0.0075 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFM10507.1 - 0.0051 16.5 0.0 0.01 15.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFM10507.1 - 0.0081 16.1 0.0 0.017 15.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFM10507.1 - 0.02 14.2 0.0 0.033 13.5 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.1 KFM10507.1 - 0.069 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 KFM10507.1 - 0.097 11.7 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CCDC32 PF14989.1 KFM10508.1 - 2.1e-55 186.6 0.4 2.6e-55 186.3 0.3 1.0 1 0 0 1 1 1 1 Coiled-coil domain containing 32 BAH PF01426.13 KFM10509.1 - 1.2e-14 54.0 0.1 3.5e-14 52.5 0.0 1.7 1 1 0 1 1 1 1 BAH domain DUF4437 PF14499.1 KFM10509.1 - 0.13 11.2 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) Acyl-CoA_dh_1 PF00441.19 KFM10510.1 - 2.5e-39 134.7 0.1 3.8e-39 134.1 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KFM10510.1 - 4.9e-34 117.2 0.0 8.5e-34 116.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KFM10510.1 - 1.7e-18 65.8 0.0 3.1e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KFM10510.1 - 3.3e-10 40.3 0.0 5.5e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 KFM10510.1 - 0.13 12.6 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal TPR_MLP1_2 PF07926.7 KFM10511.1 - 0.014 15.1 5.5 0.014 15.1 3.8 2.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein ADIP PF11559.3 KFM10511.1 - 0.025 14.4 5.6 0.025 14.4 3.9 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.6 KFM10511.1 - 0.049 13.5 1.6 0.23 11.3 1.1 2.2 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) SAP30_Sin3_bdg PF13867.1 KFM10511.1 - 0.12 12.2 1.7 15 5.5 0.3 2.6 2 0 0 2 2 2 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Mto2_bdg PF12808.2 KFM10511.1 - 0.17 11.9 4.2 0.28 11.3 0.8 2.7 1 1 1 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region EIAV_Rev PF11129.3 KFM10511.1 - 0.25 11.3 2.1 0.48 10.4 0.2 2.0 1 1 1 2 2 2 0 Rev protein of equine infectious anaemia virus Bacillus_HBL PF05791.6 KFM10511.1 - 0.51 9.6 6.2 0.15 11.4 0.4 2.2 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DivIC PF04977.10 KFM10511.1 - 0.69 9.4 14.3 0.065 12.7 1.5 3.2 2 1 1 3 3 3 0 Septum formation initiator DUF4200 PF13863.1 KFM10511.1 - 2.7 7.9 19.6 0.16 11.9 2.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) TnpV PF14198.1 KFM10511.1 - 7.8 6.4 9.5 2 8.3 1.3 2.2 2 0 0 2 2 2 0 Transposon-encoded protein TnpV Patched PF02460.13 KFM10512.1 - 5e-05 21.4 2.8 5e-05 21.4 2.0 2.3 2 0 0 2 2 2 2 Patched family DUF4594 PF15266.1 KFM10513.1 - 3e-24 86.1 7.4 3e-24 86.1 5.2 2.3 1 1 0 2 2 2 1 Domain of unknown function (DUF4594) Transglut_N PF00868.15 KFM10513.1 - 0.028 14.4 0.4 0.088 12.8 0.1 2.0 1 1 0 1 1 1 0 Transglutaminase family DUF4594 PF15266.1 KFM10514.1 - 0.0006 20.0 0.1 0.0006 20.0 0.1 3.2 2 1 1 3 3 3 1 Domain of unknown function (DUF4594) DUF605 PF04652.11 KFM10514.1 - 4.7 6.5 9.3 5.6 6.2 6.5 1.1 1 0 0 1 1 1 0 Vta1 like PI-PLC-X PF00388.14 KFM10515.1 - 5e-67 223.8 0.0 1.1e-66 222.7 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KFM10515.1 - 3.2e-44 149.6 2.1 7.8e-44 148.4 1.5 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 KFM10515.1 - 2.7e-22 78.5 0.0 7.6e-22 77.1 0.0 1.9 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 KFM10515.1 - 4.3e-07 29.6 0.0 9.8e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain Pkinase PF00069.20 KFM10516.1 - 1.3e-67 227.7 0.0 1.7e-67 227.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM10516.1 - 7.3e-45 153.0 0.0 1e-44 152.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 KFM10516.1 - 1.2e-13 51.2 0.9 3.2e-13 49.8 0.0 2.2 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 KFM10516.1 - 1.1e-06 27.7 0.0 1.7e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFM10516.1 - 0.11 12.1 0.3 6.7 6.3 0.0 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family Mad3_BUB1_I PF08311.7 KFM10517.1 - 1.2e-46 157.6 0.2 2.7e-46 156.4 0.2 1.7 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 KFM10517.1 - 0.00033 19.8 0.9 0.00052 19.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain MerR-DNA-bind PF09278.6 KFM10517.1 - 0.0014 18.9 3.9 0.0064 16.8 2.7 2.2 1 0 0 1 1 1 1 MerR, DNA binding DUF3987 PF13148.1 KFM10517.1 - 6.8 5.1 9.5 16 3.9 6.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Cadherin PF00028.12 KFM10518.1 - 4.3e-18 65.3 3.3 5.2e-09 36.2 0.1 2.4 2 0 0 2 2 2 2 Cadherin domain Hormone_2 PF00123.15 KFM10519.1 - 2.3e-22 78.4 0.2 2.5e-12 46.3 0.0 2.3 2 0 0 2 2 2 2 Peptide hormone PP1_inhibitor PF05361.7 KFM10519.1 - 0.079 12.6 0.0 0.13 11.9 0.0 1.4 1 1 0 1 1 1 0 PKC-activated protein phosphatase-1 inhibitor 7tm_1 PF00001.16 KFM10520.1 - 1.8e-55 187.9 4.7 2e-55 187.7 3.3 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM10520.1 - 1.3e-07 31.0 9.0 0.0001 21.5 0.1 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM10520.1 - 0.00083 18.5 5.8 0.01 14.9 1.7 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx SAND PF01342.16 KFM10521.1 - 4.9e-26 90.2 0.0 1.4e-25 88.7 0.0 1.8 2 0 0 2 2 2 1 SAND domain zf-MYND PF01753.13 KFM10521.1 - 1.3e-10 40.9 15.8 1.3e-10 40.9 10.9 2.0 2 0 0 2 2 2 1 MYND finger Transmemb_17 PF09799.4 KFM10522.1 - 1.4e-24 86.5 11.1 1.9e-24 86.0 7.7 1.2 1 0 0 1 1 1 1 Predicted membrane protein PTB PF08416.8 KFM10523.1 - 7.3e-47 158.5 3.2 1.4e-46 157.6 2.2 1.5 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SH3_1 PF00018.23 KFM10523.1 - 1.6e-10 40.1 0.1 4.5e-10 38.7 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFM10523.1 - 6.6e-09 35.2 0.0 1.7e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PID PF00640.18 KFM10523.1 - 3.9e-06 26.9 2.0 7.7e-06 25.9 0.3 2.1 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) SH3_2 PF07653.12 KFM10523.1 - 7.6e-06 25.3 0.0 1.5e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 KFM10523.1 - 0.036 14.2 0.0 0.089 13.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain Transaldolase PF00923.14 KFM10524.1 - 1.1e-97 326.5 0.0 1.3e-97 326.4 0.0 1.0 1 0 0 1 1 1 1 Transaldolase DJ-1_PfpI PF01965.19 KFM10525.1 - 2.8e-09 36.5 0.0 3.5e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Alpha_GJ PF03229.8 KFM10526.1 - 0.0021 18.4 3.4 0.0021 18.4 2.4 1.5 1 1 1 2 2 2 1 Alphavirus glycoprotein J Cyto_ox_2 PF02322.10 KFM10526.1 - 0.11 11.6 0.0 0.12 11.5 0.0 1.0 1 0 0 1 1 1 0 Cytochrome oxidase subunit II NACHT PF05729.7 KFM10527.1 - 1.6e-36 125.4 0.0 3.6e-36 124.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain PYRIN PF02758.11 KFM10527.1 - 1.6e-15 56.5 0.0 5.5e-15 54.8 0.0 1.9 1 0 0 1 1 1 1 PAAD/DAPIN/Pyrin domain FISNA PF14484.1 KFM10527.1 - 0.00054 19.8 0.0 0.0012 18.8 0.0 1.6 1 0 0 1 1 1 1 Fish-specific NACHT associated domain LRR_6 PF13516.1 KFM10527.1 - 0.00072 19.3 0.9 0.0063 16.4 0.2 2.7 2 0 0 2 2 2 1 Leucine Rich repeat AAA_16 PF13191.1 KFM10527.1 - 0.00083 19.3 0.0 0.0019 18.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 KFM10527.1 - 0.0011 18.5 0.3 0.0075 15.7 0.0 2.3 1 1 0 2 2 2 1 FtsK/SpoIIIE family AAA PF00004.24 KFM10527.1 - 0.002 18.3 0.0 0.0041 17.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFM10527.1 - 0.0058 16.7 0.0 0.017 15.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KFM10527.1 - 0.0059 15.7 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 KFM10527.1 - 0.01 15.5 0.0 0.075 12.7 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain NB-ARC PF00931.17 KFM10527.1 - 0.033 13.0 0.0 0.065 12.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.1 KFM10527.1 - 0.035 14.0 0.0 0.092 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain NAGidase PF07555.8 KFM10527.1 - 0.18 10.6 0.0 0.42 9.4 0.0 1.5 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase COLFI PF01410.13 KFM10528.1 - 1.1e-52 178.5 0.0 1.2e-52 178.4 0.0 1.0 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Lipase_GDSL PF00657.17 KFM10529.1 - 1e-89 300.4 0.0 4.3e-30 105.2 0.0 3.2 3 0 0 3 3 3 3 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KFM10529.1 - 1.3e-27 97.0 0.0 7.9e-09 35.8 0.1 4.7 3 2 0 3 3 3 3 GDSL-like Lipase/Acylhydrolase family PLDc PF00614.17 KFM10529.1 - 0.3 10.9 1.4 44 4.0 0.0 3.2 3 0 0 3 3 3 0 Phospholipase D Active site motif bZIP_1 PF00170.16 KFM10530.1 - 2e-09 37.2 20.0 3.1e-09 36.6 13.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFM10530.1 - 1.2e-06 28.1 19.1 2.1e-06 27.4 13.2 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KFM10530.1 - 2.4e-05 24.5 14.1 4.1e-05 23.7 9.8 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor HAUS6_N PF14661.1 KFM10530.1 - 0.018 14.4 1.9 0.023 14.0 1.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus V_ATPase_I PF01496.14 KFM10530.1 - 0.21 9.4 1.8 0.24 9.1 1.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 KFM10530.1 - 0.82 9.2 6.5 1.3 8.5 4.5 1.3 1 0 0 1 1 1 0 IncA protein DUF342 PF03961.8 KFM10530.1 - 1.1 7.6 4.3 1.4 7.2 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2681 PF10883.3 KFM10530.1 - 1.3 9.2 6.3 2.6 8.3 4.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) APG6 PF04111.7 KFM10530.1 - 1.6 7.7 8.2 2.2 7.2 5.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Pox_G5 PF04599.7 KFM10530.1 - 4.9 5.7 6.4 6.9 5.2 4.4 1.1 1 0 0 1 1 1 0 Poxvirus G5 protein BRE PF06113.7 KFM10531.1 - 6.4e-228 755.1 0.1 7.2e-228 754.9 0.1 1.0 1 0 0 1 1 1 1 Brain and reproductive organ-expressed protein (BRE) UQ_con PF00179.21 KFM10531.1 - 0.0029 17.0 3.6 0.71 9.3 0.1 2.7 3 0 0 3 3 3 2 Ubiquitin-conjugating enzyme PfkB PF00294.19 KFM10532.1 - 2.1e-58 197.8 0.2 2.6e-58 197.5 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 KFM10532.1 - 6.9e-07 28.7 0.0 1.1e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase CoA_binding_2 PF13380.1 KFM10532.1 - 0.0024 18.0 0.1 0.022 14.9 0.0 2.1 2 0 0 2 2 2 1 CoA binding domain Aldolase PF01081.14 KFM10532.1 - 0.028 13.6 1.0 5.1 6.2 0.2 2.2 2 0 0 2 2 2 0 KDPG and KHG aldolase Mur_ligase PF01225.20 KFM10532.1 - 0.034 14.1 0.3 0.23 11.5 0.1 2.4 2 1 1 3 3 3 0 Mur ligase family, catalytic domain BSP_II PF05432.6 KFM10535.1 - 0.002 17.4 4.8 0.002 17.4 3.3 3.4 3 1 0 3 3 3 1 Bone sialoprotein II (BSP-II) Myc_N PF01056.13 KFM10535.1 - 0.0025 17.0 1.4 0.0025 17.0 1.0 2.6 2 1 0 2 2 2 1 Myc amino-terminal region dsrm PF00035.20 KFM10535.1 - 0.0025 18.3 0.0 0.0066 16.9 0.0 1.8 1 0 0 1 1 1 1 Double-stranded RNA binding motif Dicer_dimer PF03368.9 KFM10535.1 - 0.0038 16.9 0.1 0.012 15.3 0.0 1.9 2 0 0 2 2 2 1 Dicer dimerisation domain Bromo_TP PF07524.8 KFM10536.1 - 4.5e-21 74.3 0.3 1.1e-20 73.1 0.0 1.7 2 0 0 2 2 2 1 Bromodomain associated LRR_8 PF13855.1 KFM10540.1 - 2.2e-28 97.7 17.5 1.2e-12 47.4 2.1 3.5 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KFM10540.1 - 2.6e-19 68.3 19.7 1.6e-06 27.5 2.8 4.6 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) I-set PF07679.11 KFM10540.1 - 5.3e-15 55.0 0.0 1.1e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_1 PF00560.28 KFM10540.1 - 2.6e-12 44.9 21.6 0.043 13.8 0.5 8.0 8 0 0 8 8 7 4 Leucine Rich Repeat LRR_5 PF13306.1 KFM10540.1 - 3.9e-12 45.9 0.1 1.7e-10 40.7 0.0 2.1 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) Ig_3 PF13927.1 KFM10540.1 - 1.2e-07 32.0 0.3 8.5e-07 29.3 0.0 2.6 2 1 1 3 3 3 1 Immunoglobulin domain fn3 PF00041.16 KFM10540.1 - 1.6e-07 31.3 0.0 6.3e-07 29.4 0.0 2.1 1 0 0 1 1 1 1 Fibronectin type III domain Ig_2 PF13895.1 KFM10540.1 - 3.8e-06 26.9 0.1 1.4e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.20 KFM10540.1 - 2.5e-05 24.2 0.0 7e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain LRR_9 PF14580.1 KFM10540.1 - 6.8e-05 22.5 3.8 0.003 17.1 0.4 2.3 1 1 1 2 2 2 2 Leucine-rich repeat V-set PF07686.12 KFM10540.1 - 0.0064 16.3 0.0 0.022 14.6 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin V-set domain LRR_7 PF13504.1 KFM10540.1 - 0.03 14.4 21.0 2.2 8.8 0.1 7.0 8 0 0 8 8 6 0 Leucine rich repeat Mob_synth_C PF06463.8 KFM10541.1 - 1.5e-40 137.8 0.0 2.2e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 KFM10541.1 - 2.8e-27 95.9 0.1 4.5e-27 95.2 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 KFM10541.1 - 8.7e-10 38.8 0.0 1.8e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 KFM10541.1 - 2.8e-08 33.8 0.1 1.1e-07 31.8 0.0 2.1 3 0 0 3 3 3 1 4Fe-4S single cluster domain Lipoprotein_9 PF03180.9 KFM10541.1 - 0.088 11.6 0.1 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 NLPA lipoprotein MoaC PF01967.16 KFM10542.1 - 2.1e-28 98.6 0.1 3.1e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 MoaC family FH2 PF02181.18 KFM10544.1 - 2.5e-109 365.5 8.4 2.5e-109 365.5 5.8 2.0 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 KFM10544.1 - 4e-61 205.8 2.8 4e-61 205.8 2.0 3.1 4 0 0 4 4 4 1 Diaphanous FH3 Domain Drf_GBD PF06371.8 KFM10544.1 - 1.3e-50 171.3 0.5 1.3e-50 171.3 0.4 3.0 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Kinesin PF00225.18 KFM10545.1 - 4.2e-99 331.4 0.1 4.2e-99 331.4 0.1 1.9 2 0 0 2 2 2 1 Kinesin motor domain AAA_22 PF13401.1 KFM10545.1 - 0.053 13.6 0.3 0.38 10.8 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KFM10545.1 - 0.66 9.3 0.0 0.66 9.3 0.0 2.4 2 1 0 2 2 2 0 AAA-like domain Ion_trans_2 PF07885.11 KFM10546.1 - 7.9e-34 115.2 15.5 3.5e-19 68.2 0.1 2.2 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.26 KFM10546.1 - 0.00012 21.3 10.7 0.011 15.0 1.2 2.2 1 1 1 2 2 2 2 Ion transport protein FUSC_2 PF13515.1 KFM10546.1 - 0.7 9.8 10.6 0.23 11.3 4.0 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein-like Ion_trans_2 PF07885.11 KFM10547.1 - 5.8e-23 80.4 8.9 3.3e-13 49.1 2.3 2.3 2 0 0 2 2 2 2 Ion channel Ion_trans_2 PF07885.11 KFM10548.1 - 1.7e-30 104.5 19.4 4.1e-18 64.8 1.6 2.3 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.26 KFM10548.1 - 0.059 12.6 9.7 0.28 10.4 0.4 2.4 2 0 0 2 2 2 0 Ion transport protein UPF0542 PF15086.1 KFM10548.1 - 0.24 11.1 2.7 0.15 11.7 0.3 1.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 7tm_2 PF00002.19 KFM10549.1 - 5e-79 264.8 24.6 6.6e-79 264.4 17.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 KFM10549.1 - 8.1e-17 60.9 3.3 2.1e-16 59.6 2.3 1.8 1 0 0 1 1 1 1 Hormone receptor domain Dicty_CAR PF05462.6 KFM10549.1 - 2.7e-06 26.5 17.7 4.7e-06 25.7 12.2 1.4 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Glyoxalase PF00903.20 KFM10550.1 - 2.9e-26 91.9 0.0 3.3e-26 91.7 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KFM10550.1 - 1.6e-17 64.0 0.1 2.8e-17 63.2 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KFM10550.1 - 4.3e-11 42.7 0.0 3.6e-10 39.8 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 KFM10550.1 - 0.066 13.1 0.0 0.2 11.5 0.0 1.8 2 1 0 2 2 2 0 Glyoxalase-like domain BTB PF00651.26 KFM10551.1 - 9e-28 96.4 0.3 3.5e-26 91.3 0.0 2.6 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.10 KFM10551.1 - 1.7e-23 82.3 0.3 3.8e-22 78.0 0.2 2.4 1 1 1 2 2 2 1 BTB And C-terminal Kelch F5_F8_type_C PF00754.20 KFM10551.1 - 7.1e-17 61.4 0.2 3.7e-07 30.0 0.1 2.2 2 0 0 2 2 2 2 F5/8 type C domain zf-AN1 PF01428.11 KFM10552.1 - 3e-11 42.9 7.0 8.4e-11 41.5 4.9 1.8 1 0 0 1 1 1 1 AN1-like Zinc finger IBR PF01485.16 KFM10552.1 - 0.12 12.2 8.8 0.053 13.3 3.5 2.1 2 0 0 2 2 2 0 IBR domain zf-RING_4 PF14570.1 KFM10552.1 - 0.47 10.0 4.8 1.1 8.8 3.3 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain I-set PF07679.11 KFM10553.1 - 2.9e-63 209.7 0.2 8.1e-12 44.8 0.0 6.4 6 0 0 6 6 6 6 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM10553.1 - 6.5e-56 186.4 8.7 7.5e-09 35.5 0.0 6.9 7 0 0 7 7 7 6 Immunoglobulin domain MAM PF00629.18 KFM10553.1 - 2.5e-50 170.3 0.0 1.1e-49 168.2 0.0 2.1 2 0 0 2 2 2 1 MAM domain ig PF00047.20 KFM10553.1 - 3.3e-41 139.2 9.2 8.3e-08 32.2 0.0 7.3 7 0 0 7 7 7 6 Immunoglobulin domain Ig_3 PF13927.1 KFM10553.1 - 5.9e-36 122.7 19.2 4.5e-08 33.4 0.1 7.2 7 1 0 7 7 7 6 Immunoglobulin domain V-set PF07686.12 KFM10553.1 - 2.6e-33 114.3 11.7 2.2e-06 27.5 0.0 9.6 6 3 1 7 7 7 5 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM10553.1 - 2.3e-11 43.4 5.8 0.028 14.3 0.0 5.7 6 0 0 6 6 6 4 CD80-like C2-set immunoglobulin domain C1-set PF07654.10 KFM10553.1 - 1.7e-05 24.7 2.2 0.16 12.0 0.0 4.7 4 1 0 4 4 4 1 Immunoglobulin C1-set domain BiPBP_C PF06832.7 KFM10553.1 - 0.0063 16.4 0.0 0.16 11.8 0.0 3.1 3 0 0 3 3 3 1 Penicillin-Binding Protein C-terminus Family CCDC-167 PF15188.1 KFM10555.1 - 4.6e-28 96.9 3.8 5.1e-28 96.8 2.7 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 Strep_SA_rep PF06696.6 KFM10555.1 - 0.046 13.5 0.4 0.11 12.2 0.3 1.7 1 0 0 1 1 1 0 Streptococcal surface antigen repeat Mnd1 PF03962.10 KFM10555.1 - 0.26 10.9 3.0 0.29 10.7 2.1 1.0 1 0 0 1 1 1 0 Mnd1 family Snf7 PF03357.16 KFM10555.1 - 0.31 10.4 3.7 0.22 10.9 1.1 1.6 1 1 0 1 1 1 0 Snf7 priB_priC PF07445.7 KFM10555.1 - 0.51 9.7 3.9 0.27 10.7 0.5 1.8 1 1 1 2 2 2 0 Primosomal replication protein priB and priC FtsJ PF01728.14 KFM10556.1 - 1e-37 129.8 0.0 2e-37 128.9 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase G-patch PF01585.18 KFM10556.1 - 1.2e-12 47.4 2.5 1.2e-12 47.4 1.7 2.1 2 0 0 2 2 2 1 G-patch domain WW PF00397.21 KFM10556.1 - 0.00044 20.0 0.7 0.0056 16.5 0.0 2.4 2 0 0 2 2 2 1 WW domain mRNA_cap_enzyme PF01331.14 KFM10556.1 - 0.0028 17.3 0.0 0.0073 16.0 0.0 1.6 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain DNA_ligase_A_M PF01068.16 KFM10556.1 - 0.021 14.2 0.5 0.055 12.8 0.0 1.9 2 0 0 2 2 2 0 ATP dependent DNA ligase domain G-patch_2 PF12656.2 KFM10556.1 - 0.055 13.3 1.5 0.17 11.7 1.0 1.8 1 0 0 1 1 1 0 DExH-box splicing factor binding site zf-C3HC4 PF00097.20 KFM10557.1 - 1.1e-10 40.9 12.9 1.8e-10 40.2 7.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM10557.1 - 1.1e-10 41.1 10.8 1.6e-10 40.5 6.5 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFM10557.1 - 1.5e-10 40.6 8.0 2.6e-10 39.8 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFM10557.1 - 9.4e-10 38.2 9.3 1.8e-09 37.3 5.2 2.3 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 KFM10557.1 - 1.2e-08 34.7 12.3 1.5e-08 34.4 7.6 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM10557.1 - 7.8e-08 31.9 9.0 7.8e-08 31.9 6.3 1.8 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KFM10557.1 - 1.2e-06 28.1 6.6 3.7e-05 23.3 0.8 2.5 2 1 0 2 2 2 2 RING-type zinc-finger zf-RING_6 PF14835.1 KFM10557.1 - 2.4e-05 24.0 5.1 3.8e-05 23.3 3.5 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 KFM10557.1 - 7.7e-05 22.7 10.0 0.0002 21.4 6.3 2.1 2 1 0 2 2 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KFM10557.1 - 0.00039 20.2 3.7 0.00081 19.1 2.6 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FdhE PF04216.7 KFM10557.1 - 0.0077 15.9 3.9 0.0077 15.9 2.7 1.4 1 1 0 1 1 1 1 Protein involved in formate dehydrogenase formation Prok-RING_4 PF14447.1 KFM10557.1 - 0.017 14.6 5.9 0.037 13.5 4.1 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zinc-ribbons_6 PF07191.7 KFM10557.1 - 0.15 11.9 0.3 0.15 11.9 0.2 2.4 1 1 1 2 2 2 0 zinc-ribbons zf-RING_4 PF14570.1 KFM10557.1 - 0.18 11.3 10.6 1.3 8.7 7.5 2.3 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF1644 PF07800.7 KFM10557.1 - 0.98 9.2 8.9 4.8 7.0 0.6 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1644) DZR PF12773.2 KFM10557.1 - 1.4 8.8 7.4 7.6 6.4 5.2 2.1 1 1 1 2 2 2 0 Double zinc ribbon zinc_ribbon_5 PF13719.1 KFM10557.1 - 1.5 8.4 8.0 6.4 6.4 0.3 3.3 3 1 1 4 4 4 0 zinc-ribbon domain Baculo_RING PF05883.6 KFM10557.1 - 1.5 8.6 8.9 0.55 10.0 2.7 2.4 1 1 1 2 2 2 0 Baculovirus U-box/Ring-like domain zinc_ribbon_4 PF13717.1 KFM10557.1 - 1.7 8.4 8.4 5.6 6.7 0.3 3.3 3 1 1 4 4 3 0 zinc-ribbon domain FANCL_C PF11793.3 KFM10557.1 - 3.5 7.6 11.7 3.7e+02 1.1 8.1 2.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-FCS PF06467.9 KFM10557.1 - 5.4 6.7 11.8 4 7.1 0.2 3.1 2 1 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif FHA PF00498.21 KFM10558.1 - 1.3e-10 41.2 0.0 2.4e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 FHA domain tRNA-synt_2c PF01411.14 KFM10559.1 - 4.6e-167 556.6 0.0 6.4e-167 556.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 KFM10559.1 - 2.3e-07 30.5 1.3 8.7e-07 28.7 0.1 2.6 3 0 0 3 3 3 1 Threonyl and Alanyl tRNA synthetase second additional domain LRR_6 PF13516.1 KFM10560.1 - 2.1e-15 54.9 19.9 0.0087 16.0 0.0 8.5 9 0 0 9 9 9 5 Leucine Rich repeat LRR_4 PF12799.2 KFM10560.1 - 5.8e-06 25.7 15.3 0.00099 18.6 0.4 5.1 3 1 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM10560.1 - 2.4e-05 23.9 15.4 0.00099 18.8 1.3 4.8 4 1 1 5 5 5 3 Leucine rich repeat LRR_1 PF00560.28 KFM10560.1 - 0.00073 19.2 11.6 0.94 9.7 0.0 6.2 7 0 0 7 7 7 2 Leucine Rich Repeat TMEM151 PF14857.1 KFM10561.1 - 3e-231 767.3 18.7 3.5e-231 767.1 12.9 1.0 1 0 0 1 1 1 1 TMEM151 family UAA PF08449.6 KFM10562.1 - 1.4e-89 300.0 21.2 1.8e-89 299.6 14.7 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 KFM10562.1 - 5.9e-06 26.3 26.7 1.4e-05 25.1 9.0 3.1 3 1 1 4 4 4 2 EamA-like transporter family TPT PF03151.11 KFM10562.1 - 0.0078 15.8 19.4 0.069 12.7 13.4 2.6 1 1 0 1 1 1 1 Triose-phosphate Transporter family Neurensin PF14927.1 KFM10562.1 - 1.7 8.0 5.1 1.9 7.8 0.2 2.7 1 1 0 2 2 2 0 Neurensin HSP90 PF00183.13 KFM10563.1 - 5.3e-267 886.4 36.6 6.4e-267 886.1 25.4 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 KFM10563.1 - 7.5e-11 41.7 0.0 1.4e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KFM10563.1 - 1.1e-10 41.3 0.1 4.6e-10 39.2 0.1 2.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CDC45 PF02724.9 KFM10563.1 - 0.36 8.8 13.1 0.65 7.9 9.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Spectrin PF00435.16 KFM10565.1 - 0.035 14.3 2.2 10 6.4 0.9 2.7 2 1 0 2 2 2 0 Spectrin repeat MerR-DNA-bind PF09278.6 KFM10565.1 - 0.26 11.7 3.2 13 6.2 0.4 2.9 3 0 0 3 3 3 0 MerR, DNA binding Peptidase_C2 PF00648.16 KFM10566.1 - 4.6e-150 498.6 0.0 6.6e-150 498.1 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 KFM10566.1 - 2.6e-60 202.3 0.0 4.7e-60 201.4 0.0 1.5 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_6 PF13405.1 KFM10566.1 - 5.2e-07 29.0 0.4 0.016 15.0 0.0 5.0 3 1 1 4 4 4 1 EF-hand domain EF-hand_1 PF00036.27 KFM10566.1 - 2.8e-06 26.2 1.0 0.031 13.5 0.0 4.4 5 0 0 5 5 5 2 EF hand EF-hand_7 PF13499.1 KFM10566.1 - 1.1e-05 25.4 3.0 0.1 12.7 0.0 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KFM10566.1 - 1.2e-05 24.7 0.9 0.0014 18.2 0.1 3.7 3 0 0 3 3 3 1 EF-hand domain pair DUF221 PF02714.10 KFM10567.1 - 2.8e-94 315.6 21.1 5.6e-94 314.6 14.6 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KFM10567.1 - 5.6e-20 71.4 0.0 5.6e-20 71.4 0.0 5.8 6 1 1 7 7 7 2 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KFM10567.1 - 1.8e-11 44.4 0.2 3.9e-11 43.3 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_1 PF00076.17 KFM10567.1 - 0.045 13.3 0.1 3.1 7.4 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4006 PF13179.1 KFM10567.1 - 5.6 6.5 5.5 52 3.4 0.2 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF4006) Ribosomal_L14 PF00238.14 KFM10568.1 - 1.5e-24 86.0 0.0 1.8e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e VEGF_C PF14554.1 KFM10570.1 - 3.1e-28 97.3 15.1 3.1e-28 97.3 10.5 2.4 2 0 0 2 2 2 1 VEGF heparin-binding domain PDGF PF00341.12 KFM10570.1 - 1.4e-27 95.6 5.7 1.4e-27 95.6 4.0 2.3 2 1 0 2 2 2 1 PDGF/VEGF domain Radial_spoke PF04712.7 KFM10572.1 - 6.9e-07 28.3 0.1 6.5e-05 21.8 0.0 2.2 1 1 1 2 2 2 2 Radial spokehead-like protein EHN PF06441.7 KFM10573.1 - 4.1e-36 123.2 0.3 7e-36 122.5 0.2 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KFM10573.1 - 3.9e-16 59.6 0.0 2.1e-15 57.2 0.0 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFM10573.1 - 4.5e-13 49.3 0.0 9.5e-12 44.9 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold p31comet PF06581.7 KFM10574.1 - 6.2e-68 228.5 0.0 6.9e-68 228.3 0.0 1.0 1 0 0 1 1 1 1 Mad1 and Cdc20-bound-Mad2 binding GTP_EFTU PF00009.22 KFM10575.1 - 7.3e-28 97.2 0.0 1.2e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KFM10575.1 - 2.2e-09 37.3 0.9 6.8e-09 35.7 0.6 1.9 1 1 1 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KFM10575.1 - 0.00014 21.8 0.1 0.00044 20.3 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 KFM10575.1 - 0.00083 18.8 0.1 12 5.3 0.0 3.5 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 KFM10575.1 - 0.0016 18.3 0.0 0.004 17.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KFM10575.1 - 0.014 15.9 0.0 0.14 12.7 0.0 2.5 1 1 0 1 1 1 0 Miro-like protein SRPRB PF09439.5 KFM10575.1 - 0.04 13.1 0.1 4.9 6.3 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 KFM10575.1 - 0.048 12.9 0.1 3 7.1 0.0 2.8 3 0 0 3 3 3 0 Ferrous iron transport protein B Dynamin_N PF00350.18 KFM10575.1 - 0.075 12.8 0.1 1.8 8.3 0.1 2.3 1 1 1 2 2 2 0 Dynamin family DUF4461 PF14688.1 KFM10575.1 - 0.097 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4461) ATP_bind_1 PF03029.12 KFM10575.1 - 0.12 11.9 0.1 10 5.5 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein IMS_C PF11799.3 KFM10576.1 - 1.4e-12 47.6 0.0 3.5e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS PF00817.15 KFM10576.1 - 8.8e-08 32.0 0.0 9.4e-07 28.7 0.0 2.4 2 0 0 2 2 2 1 impB/mucB/samB family DUF627 PF04781.7 KFM10576.1 - 0.15 11.6 0.0 0.55 9.8 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF627) Ribosomal_60s PF00428.14 KFM10576.1 - 4.6 7.6 7.4 1.3 9.5 0.5 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Xpo1 PF08389.7 KFM10577.1 - 5.3e-36 123.7 3.6 2.2e-35 121.7 2.1 2.4 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.14 KFM10577.1 - 0.00041 20.2 0.0 0.0019 18.0 0.0 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain RNA_pol_A_bac PF01000.21 KFM10578.1 - 3.3e-30 104.5 0.0 5.3e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KFM10578.1 - 2e-16 58.8 0.0 2.5e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Yip1 PF04893.12 KFM10579.1 - 7.1e-06 25.6 17.8 1.2e-05 24.9 12.3 1.5 1 1 0 1 1 1 1 Yip1 domain Romo1 PF10247.4 KFM10579.1 - 0.013 15.6 2.0 0.04 14.0 1.3 2.0 1 1 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 LRR_6 PF13516.1 KFM10580.1 - 1.6e-13 49.1 6.7 0.014 15.4 0.0 5.8 6 0 0 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.28 KFM10580.1 - 3.2e-07 29.4 1.1 5.2 7.4 0.0 5.3 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_4 PF12799.2 KFM10580.1 - 7.2e-07 28.6 5.1 0.0038 16.8 0.0 4.0 3 2 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 KFM10580.1 - 6.2e-06 25.5 1.9 11 6.7 0.0 5.4 5 0 0 5 5 5 1 Leucine rich repeat LRR_8 PF13855.1 KFM10580.1 - 0.002 17.8 2.4 2.3 8.0 0.1 3.8 3 2 0 3 3 3 2 Leucine rich repeat Pilt PF15453.1 KFM10581.1 - 2.4e-122 408.5 23.2 4.7e-94 315.6 9.0 3.1 2 2 1 3 3 3 2 Protein incorporated later into Tight Junctions Fib_alpha PF08702.5 KFM10581.1 - 0.057 13.5 5.6 0.1 12.7 3.4 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Lebercilin PF15619.1 KFM10581.1 - 0.15 11.4 18.7 0.76 9.1 13.0 2.0 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease ERM PF00769.14 KFM10581.1 - 0.19 11.2 15.0 0.37 10.2 10.4 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family V_ATPase_I PF01496.14 KFM10581.1 - 4.5 5.0 6.9 6 4.5 4.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 KFM10581.1 - 4.5 6.8 19.1 90 2.5 13.1 2.3 1 1 1 2 2 2 0 IncA protein Syntaxin-6_N PF09177.6 KFM10581.1 - 6.5 7.2 10.5 0.67 10.3 1.0 3.0 2 1 1 3 3 3 0 Syntaxin 6, N-terminal EGF PF00008.22 KFM10582.1 - 7.1e-29 99.3 66.5 3.1e-08 33.4 5.8 6.2 6 0 0 6 6 6 5 EGF-like domain hEGF PF12661.2 KFM10582.1 - 1e-11 44.0 46.5 0.0082 16.1 1.3 7.5 6 0 0 6 6 6 5 Human growth factor-like EGF EGF_2 PF07974.8 KFM10582.1 - 1.3e-06 28.4 85.4 0.027 14.6 5.6 6.4 6 0 0 6 6 6 4 EGF-like domain EGF_CA PF07645.10 KFM10582.1 - 0.027 14.4 71.5 0.078 12.9 4.8 6.2 3 1 2 5 5 5 0 Calcium-binding EGF domain Laminin_EGF PF00053.19 KFM10582.1 - 0.15 11.9 67.7 4.9 7.1 4.0 6.4 2 2 4 6 6 6 0 Laminin EGF-like (Domains III and V) EGF_3 PF12947.2 KFM10582.1 - 0.56 10.2 61.4 0.1 12.5 3.2 5.9 4 1 1 5 5 5 0 EGF domain ABC_membrane PF00664.18 KFM10583.1 - 3.1e-56 190.8 34.9 4.1e-30 105.1 8.9 2.9 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFM10583.1 - 7e-55 185.0 0.1 2.1e-32 112.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KFM10583.1 - 7.2e-11 41.7 5.8 0.016 14.4 0.1 4.3 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 KFM10583.1 - 2.4e-07 30.5 0.6 0.00055 19.4 0.0 2.8 3 0 0 3 3 3 2 AAA-like domain AAA_29 PF13555.1 KFM10583.1 - 2.8e-07 29.9 0.8 0.012 15.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.12 KFM10583.1 - 7e-07 29.2 0.1 0.044 13.5 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_21 PF13304.1 KFM10583.1 - 7.7e-07 29.3 0.1 0.081 12.8 0.0 3.9 4 0 0 4 4 4 1 AAA domain MMR_HSR1 PF01926.18 KFM10583.1 - 1.6e-06 28.0 0.4 0.052 13.5 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase MobB PF03205.9 KFM10583.1 - 6.7e-06 25.8 0.7 0.022 14.4 0.1 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 KFM10583.1 - 2.5e-05 24.3 3.0 0.12 12.4 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain ArgK PF03308.11 KFM10583.1 - 0.00026 19.8 1.1 0.036 12.8 0.1 2.2 2 0 0 2 2 2 1 ArgK protein AAA_25 PF13481.1 KFM10583.1 - 0.00028 20.3 0.2 0.34 10.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KFM10583.1 - 0.00071 19.9 6.9 0.31 11.3 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KFM10583.1 - 0.00092 20.0 0.0 1.7 9.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KFM10583.1 - 0.0019 17.7 0.1 1.3 8.4 0.0 2.7 3 0 0 3 3 2 1 FtsK/SpoIIIE family AAA_30 PF13604.1 KFM10583.1 - 0.0021 17.7 0.5 1.8 8.1 0.0 3.2 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 KFM10583.1 - 0.0023 16.8 0.6 1.2 7.9 0.0 2.6 3 0 0 3 3 3 2 Type II/IV secretion system protein Miro PF08477.8 KFM10583.1 - 0.01 16.3 4.7 1.3 9.5 0.5 2.6 2 0 0 2 2 2 0 Miro-like protein DUF258 PF03193.11 KFM10583.1 - 0.012 14.8 0.3 5.3 6.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 TrwB_AAD_bind PF10412.4 KFM10583.1 - 0.012 14.2 0.4 1.1 7.7 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain KAP_NTPase PF07693.9 KFM10583.1 - 0.02 13.8 0.0 0.44 9.4 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain CbiA PF01656.18 KFM10583.1 - 0.024 14.0 0.7 7.8 5.8 0.2 2.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.1 KFM10583.1 - 0.026 14.6 3.5 1.5 8.9 0.3 3.4 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KFM10583.1 - 0.049 13.9 0.1 2.2 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 KFM10583.1 - 0.072 12.6 0.2 11 5.4 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF815 PF05673.8 KFM10583.1 - 0.092 11.6 0.1 5 5.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.17 KFM10583.1 - 0.15 10.9 2.5 1.9 7.2 0.1 2.5 2 0 0 2 2 2 0 NB-ARC domain APS_kinase PF01583.15 KFM10583.1 - 0.23 11.0 1.3 8 6.0 0.1 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_PrkA PF08298.6 KFM10583.1 - 0.25 10.0 0.1 1.1 7.9 0.0 2.1 3 0 0 3 3 3 0 PrkA AAA domain Arch_ATPase PF01637.13 KFM10583.1 - 0.28 10.8 1.4 2.8 7.5 0.0 2.6 3 0 0 3 3 2 0 Archaeal ATPase DEAD PF00270.24 KFM10583.1 - 0.29 10.5 4.4 15 5.0 0.6 4.2 4 1 0 4 4 4 0 DEAD/DEAH box helicase RNA_helicase PF00910.17 KFM10583.1 - 0.33 11.1 0.5 40 4.4 0.0 3.1 3 0 0 3 3 3 0 RNA helicase NTPase_1 PF03266.10 KFM10583.1 - 0.35 10.5 1.1 5.2 6.7 0.0 2.6 3 0 0 3 3 2 0 NTPase cobW PF02492.14 KFM10583.1 - 0.42 10.0 3.5 4.6 6.6 0.2 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.7 KFM10583.1 - 0.43 9.8 2.3 2.5 7.3 0.2 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein Dynamin_N PF00350.18 KFM10583.1 - 2.9 7.6 9.7 0.3 10.8 0.5 2.9 3 0 0 3 3 2 0 Dynamin family zf-C2H2_jaz PF12171.3 KFM10584.1 - 0.00037 20.5 1.8 0.00037 20.5 1.3 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFM10584.1 - 0.016 15.3 2.4 1.9 8.6 0.2 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KFM10584.1 - 5.9 7.2 14.8 0.15 12.2 1.3 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF2465 PF10239.4 KFM10585.1 - 5.9e-135 449.5 0.0 7.1e-135 449.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2465) RasGEF PF00617.14 KFM10586.1 - 3.9e-47 160.4 0.4 6.7e-47 159.6 0.2 1.4 1 0 0 1 1 1 1 RasGEF domain EF-hand_7 PF13499.1 KFM10586.1 - 1.1e-12 47.8 0.1 8.1e-06 25.8 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain pair C1_1 PF00130.17 KFM10586.1 - 1.5e-12 47.0 9.3 3.7e-12 45.7 6.5 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RasGEF_N PF00618.15 KFM10586.1 - 1.8e-11 44.0 0.1 6.6e-11 42.2 0.0 2.0 2 0 0 2 2 2 1 RasGEF N-terminal motif EF-hand_1 PF00036.27 KFM10586.1 - 2.2e-09 35.9 6.3 0.00015 20.8 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 KFM10586.1 - 4e-09 35.5 1.6 0.00026 20.6 0.1 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 KFM10586.1 - 2.1e-08 33.1 0.3 0.0075 15.5 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 KFM10586.1 - 1.5e-05 24.5 1.6 0.091 12.3 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain pair Eno-Rase_FAD_bd PF07055.7 KFM10586.1 - 0.12 12.3 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain EGF_CA PF07645.10 KFM10587.1 - 2.8e-92 302.4 271.0 2.2e-09 37.1 4.3 19.0 19 2 1 20 20 20 15 Calcium-binding EGF domain TB PF00683.12 KFM10587.1 - 1.8e-51 171.4 67.1 1.6e-16 59.5 4.8 6.4 6 0 0 6 6 6 4 TB domain cEGF PF12662.2 KFM10587.1 - 1.4e-45 152.5 165.7 2.9e-07 30.0 2.2 18.1 18 1 0 18 18 18 12 Complement Clr-like EGF-like EGF PF00008.22 KFM10587.1 - 1.3e-38 130.4 241.2 0.00014 21.7 2.6 20.0 19 0 0 19 19 19 14 EGF-like domain EGF_3 PF12947.2 KFM10587.1 - 1.2e-18 66.6 194.2 0.00094 19.0 1.1 19.1 18 0 0 18 18 18 14 EGF domain FXa_inhibition PF14670.1 KFM10587.1 - 1.3e-05 25.2 36.0 0.00032 20.7 5.1 20.1 19 2 2 21 21 21 13 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.6 KFM10587.1 - 0.00033 20.3 12.5 0.00033 20.3 8.7 10.6 5 3 2 9 9 9 3 Plasmodium ookinete surface protein Pvs28 EGF_MSP1_1 PF12946.2 KFM10587.1 - 0.0013 18.4 1.3 0.0013 18.4 0.9 18.2 20 0 0 20 20 20 6 MSP1 EGF domain 1 hEGF PF12661.2 KFM10587.1 - 0.0056 16.6 2.9 0.0056 16.6 2.0 14.9 13 0 0 13 13 13 1 Human growth factor-like EGF TPR_11 PF13414.1 KFM10588.1 - 4.9e-18 64.5 7.7 4.8e-11 42.1 0.5 7.1 4 1 4 9 9 8 3 TPR repeat TPR_2 PF07719.12 KFM10588.1 - 3.4e-17 60.9 19.5 0.00072 19.2 0.0 8.9 8 1 2 10 10 10 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFM10588.1 - 6.6e-14 51.1 0.5 0.0037 17.7 0.0 7.6 3 2 4 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.23 KFM10588.1 - 8.2e-14 50.5 14.9 0.0024 17.4 0.0 7.8 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFM10588.1 - 1.4e-11 44.1 16.6 6.5e-05 22.7 0.1 7.2 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFM10588.1 - 1.6e-10 39.9 16.2 0.021 14.5 0.0 8.9 6 3 3 9 9 9 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFM10588.1 - 2.9e-09 37.3 0.5 0.00014 22.4 0.1 4.9 2 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 KFM10588.1 - 3.5e-09 36.3 2.6 1.5e-05 24.7 0.0 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFM10588.1 - 1.3e-08 34.3 3.7 0.00012 22.0 0.0 6.3 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFM10588.1 - 7.6e-06 26.1 9.3 0.0019 18.4 0.2 6.6 7 2 1 8 8 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFM10588.1 - 8.2e-06 25.2 7.3 4.4 7.3 0.4 6.6 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFM10588.1 - 0.00022 21.4 3.8 1.6 9.3 0.0 6.8 8 0 0 8 8 7 1 Tetratricopeptide repeat RPN7 PF10602.4 KFM10588.1 - 0.0011 18.3 1.6 0.68 9.2 0.0 3.9 4 0 0 4 4 4 1 26S proteasome subunit RPN7 BTAD PF03704.12 KFM10588.1 - 0.0014 18.9 0.6 0.014 15.7 0.1 2.8 2 1 0 2 2 2 1 Bacterial transcriptional activator domain Apc3 PF12895.2 KFM10588.1 - 0.0014 18.7 19.0 0.1 12.7 0.7 5.9 3 2 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.5 KFM10588.1 - 0.0042 15.9 0.0 0.87 8.2 0.0 2.4 1 1 1 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.1 KFM10588.1 - 0.14 12.1 5.1 7 6.7 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3643 PF12356.3 KFM10589.1 - 5.2e-69 230.7 2.8 1.7e-68 229.1 1.9 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3643) UQ_con PF00179.21 KFM10589.1 - 3.5e-29 101.0 0.0 8.4e-29 99.7 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme BIR PF00653.16 KFM10589.1 - 2.4e-21 75.9 2.8 8e-21 74.2 1.9 2.0 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain UEV PF05743.8 KFM10589.1 - 4.9e-05 22.9 0.0 0.00013 21.6 0.0 1.7 1 0 0 1 1 1 1 UEV domain DUF3138 PF11336.3 KFM10589.1 - 1.4 6.9 8.2 2.5 6.1 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Yip1 PF04893.12 KFM10591.1 - 4.9e-10 39.1 21.9 1.2e-09 37.9 14.9 1.8 1 1 0 1 1 1 1 Yip1 domain DUF1282 PF06930.7 KFM10591.1 - 3.5 7.2 14.9 5.1 6.7 10.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) CARD PF00619.16 KFM10592.1 - 1.1e-18 66.7 0.3 4e-18 65.0 0.0 2.1 2 1 1 3 3 3 1 Caspase recruitment domain LRR_4 PF12799.2 KFM10592.1 - 0.002 17.7 10.4 2.4 7.8 0.7 4.4 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KFM10592.1 - 0.0082 16.1 7.7 4.7 7.5 0.0 5.4 5 1 1 6 6 6 1 Leucine Rich repeat LRR_8 PF13855.1 KFM10592.1 - 0.021 14.5 11.1 3.3 7.5 0.5 4.5 2 2 3 5 5 5 0 Leucine rich repeat Oligomerisation PF02410.10 KFM10592.1 - 0.042 13.8 0.2 1.5 8.8 0.0 2.6 2 0 0 2 2 2 0 Oligomerisation domain LRR_7 PF13504.1 KFM10592.1 - 0.15 12.3 6.8 41 5.0 0.1 5.5 5 0 0 5 5 5 0 Leucine rich repeat LRR_1 PF00560.28 KFM10592.1 - 0.64 10.2 6.6 15 6.0 0.0 4.6 5 0 0 5 5 5 0 Leucine Rich Repeat BORG_CEP PF14957.1 KFM10593.1 - 6.8e-41 140.0 1.5 1e-40 139.4 1.1 1.3 1 0 0 1 1 1 1 Cdc42 effector PBD PF00786.23 KFM10593.1 - 5.2e-08 33.1 0.2 1.2e-07 32.0 0.1 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain TPR_11 PF13414.1 KFM10594.1 - 4.8e-08 32.5 4.2 1.5e-05 24.5 0.7 3.1 3 0 0 3 3 3 2 TPR repeat TPR_8 PF13181.1 KFM10594.1 - 2.6e-05 23.6 3.8 0.0039 16.8 0.9 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFM10594.1 - 4.4e-05 22.8 7.1 0.0067 15.9 1.2 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFM10594.1 - 0.0012 18.9 1.7 2.1 8.7 0.4 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFM10594.1 - 0.0012 19.1 0.1 0.1 12.9 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFM10594.1 - 0.0034 17.2 0.2 0.037 13.9 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat Sec16_C PF12931.2 KFM10594.1 - 0.0087 15.8 0.3 0.016 14.9 0.2 1.3 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 TPR_2 PF07719.12 KFM10594.1 - 0.023 14.6 11.4 0.099 12.6 0.4 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Glycophorin_A PF01102.13 KFM10594.1 - 0.12 12.1 0.7 0.34 10.6 0.0 1.9 2 0 0 2 2 2 0 Glycophorin A TPR_6 PF13174.1 KFM10594.1 - 0.32 11.5 2.8 3.8 8.1 0.1 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFM10594.1 - 0.48 11.1 2.2 8.4 7.2 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat HAD_2 PF13419.1 KFM10595.1 - 1.2e-23 84.2 0.0 1.5e-23 83.9 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFM10595.1 - 3.6e-12 45.8 0.0 2.1e-11 43.3 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 KFM10595.1 - 1.4e-11 45.2 0.0 1.6e-11 45.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF705 PF05152.7 KFM10595.1 - 0.17 10.8 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF705) Pkinase PF00069.20 KFM10596.1 - 1.4e-44 152.2 0.1 2.6e-44 151.3 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain dsrm PF00035.20 KFM10596.1 - 8.4e-31 106.3 2.6 1.8e-16 60.4 0.1 3.8 3 0 0 3 3 3 2 Double-stranded RNA binding motif Pkinase_Tyr PF07714.12 KFM10596.1 - 4.3e-27 94.8 0.7 7.5e-27 94.0 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase DND1_DSRM PF14709.1 KFM10596.1 - 0.0033 17.6 0.2 0.089 13.0 0.0 2.7 2 0 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 MutS_I PF01624.15 KFM10596.1 - 0.034 14.1 0.0 0.6 10.1 0.0 2.4 2 0 0 2 2 2 0 MutS domain I DUF4187 PF13821.1 KFM10597.1 - 8.1e-18 63.7 4.0 8.1e-18 63.7 2.8 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4187) G-patch PF01585.18 KFM10597.1 - 1.2e-15 56.9 0.9 2.6e-15 55.9 0.6 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KFM10597.1 - 2.1e-07 30.6 3.1 2.1e-07 30.6 2.2 2.5 3 2 0 3 3 3 1 DExH-box splicing factor binding site HEAT_2 PF13646.1 KFM10598.1 - 6.3e-12 45.6 19.7 0.0012 19.1 0.4 8.0 5 2 2 7 7 7 4 HEAT repeats HEAT PF02985.17 KFM10598.1 - 5.6e-09 35.3 33.9 0.48 10.6 0.8 11.5 11 0 0 11 11 11 3 HEAT repeat HisKA_3 PF07730.8 KFM10598.1 - 0.084 13.2 2.5 0.75 10.1 0.1 3.5 3 0 0 3 3 3 0 Histidine kinase WD40 PF00400.27 KFM10599.1 - 5.8e-45 149.6 13.3 1.7e-09 37.2 0.1 7.2 8 0 0 8 8 8 5 WD domain, G-beta repeat Striatin PF08232.7 KFM10599.1 - 4.3e-25 88.5 2.0 4.3e-25 88.5 1.4 2.6 3 0 0 3 3 3 1 Striatin family Nup160 PF11715.3 KFM10599.1 - 0.012 13.7 0.1 1 7.4 0.0 2.6 2 1 0 2 2 2 0 Nucleoporin Nup120/160 VWA PF00092.23 KFM10600.1 - 5.5e-80 267.2 2.9 6.1e-42 143.3 0.7 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.1 KFM10600.1 - 4.1e-28 98.6 0.1 6e-13 49.2 0.1 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain LCCL PF03815.14 KFM10600.1 - 7.7e-25 86.7 0.1 2.1e-24 85.3 0.0 1.7 1 0 0 1 1 1 1 LCCL domain VWA_3 PF13768.1 KFM10600.1 - 8.2e-07 28.8 0.0 0.0097 15.6 0.0 2.4 2 0 0 2 2 2 2 von Willebrand factor type A domain vWA-TerF-like PF10138.4 KFM10600.1 - 2.5e-05 24.2 0.2 0.064 13.0 0.0 2.3 2 0 0 2 2 2 2 vWA found in TerF C terminus VWA_CoxE PF05762.9 KFM10600.1 - 0.00015 21.0 0.0 0.063 12.4 0.0 2.4 2 0 0 2 2 2 2 VWA domain containing CoxE-like protein DUF1194 PF06707.6 KFM10600.1 - 0.00017 20.6 0.1 0.82 8.6 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF1194) Med3 PF11593.3 KFM10600.1 - 0.035 13.3 6.8 0.046 12.9 4.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Rxt3 PF08642.5 KFM10600.1 - 0.094 12.9 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 Mucin PF01456.12 KFM10600.1 - 2.1 8.1 22.6 4.4 7.0 15.7 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein 7tm_1 PF00001.16 KFM10601.1 - 9.4e-30 103.5 12.9 1.1e-29 103.4 9.0 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) FEZ PF07763.8 KFM10602.1 - 5.1e-95 317.8 15.0 6.4e-95 317.4 10.4 1.1 1 0 0 1 1 1 1 FEZ-like protein SCHIP-1 PF10148.4 KFM10602.1 - 0.0015 17.9 0.7 0.0024 17.3 0.5 1.3 1 0 0 1 1 1 1 Schwannomin-interacting protein 1 EURL PF06937.6 KFM10602.1 - 0.066 12.6 7.3 0.073 12.4 4.4 1.6 1 1 0 1 1 1 0 EURL protein 1-cysPrx_C PF10417.4 KFM10602.1 - 0.068 12.8 0.0 0.42 10.3 0.0 2.3 2 0 0 2 2 2 0 C-terminal domain of 1-Cys peroxiredoxin PmbA_TldD PF01523.11 KFM10602.1 - 0.16 11.2 2.6 0.15 11.3 0.3 1.8 2 0 0 2 2 2 0 Putative modulator of DNA gyrase Topo-VIb_trans PF09239.6 KFM10602.1 - 1 8.8 4.4 0.48 9.9 0.4 2.1 1 1 1 2 2 2 0 Topoisomerase VI B subunit, transducer MRP-L46 PF11788.3 KFM10602.1 - 1.8 9.2 8.0 0.84 10.3 2.5 2.2 1 1 1 2 2 2 0 39S mitochondrial ribosomal protein L46 Transposase_24 PF03004.9 KFM10602.1 - 2.2 8.1 6.1 9.4 6.1 0.5 2.8 2 1 1 3 3 3 0 Plant transposase (Ptta/En/Spm family) NPV_P10 PF05531.7 KFM10602.1 - 2.2 8.5 8.7 9.4 6.5 0.6 3.5 2 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein VWC PF00093.13 KFM10603.1 - 5.3e-41 138.5 248.1 2.3e-11 43.6 10.1 15.2 9 2 5 14 14 14 8 von Willebrand factor type C domain Antistasin PF02822.9 KFM10603.1 - 1.5e-16 60.3 59.5 7.8e-07 29.2 6.1 16.0 18 2 0 18 18 18 4 Antistasin family TMEM154 PF15102.1 KFM10603.1 - 0.19 11.4 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family Sulfotransfer_1 PF00685.22 KFM10604.1 - 7.1e-35 120.5 0.5 8.4e-35 120.3 0.4 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulphotransf PF09037.5 KFM10604.1 - 0.029 13.8 0.0 0.046 13.2 0.0 1.5 1 0 0 1 1 1 0 Stf0 sulphotransferase CBF PF03914.12 KFM10605.1 - 3.6e-50 169.6 2.9 2.3e-49 167.0 0.6 3.0 2 0 0 2 2 2 1 CBF/Mak21 family Methyltransf_28 PF02636.12 KFM10606.1 - 1.5e-72 244.0 0.0 2.5e-72 243.3 0.0 1.3 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF523 PF04463.7 KFM10606.1 - 0.05 13.3 0.0 0.092 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF523) Pkinase PF00069.20 KFM10607.1 - 8.3e-64 215.2 0.0 1.4e-63 214.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM10607.1 - 2.8e-33 115.0 0.0 4.3e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 KFM10607.1 - 2.9e-26 90.9 19.1 2.7e-13 49.3 2.1 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.24 KFM10607.1 - 1e-09 38.5 0.2 3e-08 33.7 0.0 2.5 1 1 1 2 2 2 1 PH domain Kinase-like PF14531.1 KFM10607.1 - 3.1e-07 29.6 0.0 2.4e-05 23.4 0.0 2.8 2 1 0 3 3 3 1 Kinase-like Kdo PF06293.9 KFM10607.1 - 3.6e-05 22.9 0.0 8.6e-05 21.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFM10607.1 - 0.028 14.1 0.0 1.1 8.8 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KFM10607.1 - 0.045 12.5 0.1 0.087 11.6 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase zf-RING-like PF08746.6 KFM10607.1 - 0.078 12.9 16.6 0.91 9.5 3.6 2.8 2 0 0 2 2 2 0 RING-like domain RIO1 PF01163.17 KFM10607.1 - 0.11 11.8 0.2 0.21 10.9 0.1 1.4 1 0 0 1 1 1 0 RIO1 family PHD PF00628.24 KFM10607.1 - 0.11 12.2 16.8 1.1 8.9 3.7 2.6 2 0 0 2 2 2 0 PHD-finger C1_3 PF07649.7 KFM10607.1 - 0.15 12.1 13.3 0.86 9.6 0.9 2.7 2 0 0 2 2 2 0 C1-like domain FYVE_2 PF02318.11 KFM10607.1 - 0.45 10.4 11.1 2 8.3 4.0 2.6 2 0 0 2 2 2 0 FYVE-type zinc finger Prok-RING_1 PF14446.1 KFM10607.1 - 0.71 9.6 16.3 0.25 11.0 1.5 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD_2 PF13831.1 KFM10607.1 - 1.6 8.0 8.9 1.1 8.5 0.4 2.8 2 0 0 2 2 2 0 PHD-finger Peptidase_M28 PF04389.12 KFM10608.1 - 7.3e-44 149.6 0.0 1e-43 149.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Cation_efflux PF01545.16 KFM10609.1 - 7.7e-44 149.8 9.7 1e-43 149.4 6.7 1.1 1 0 0 1 1 1 1 Cation efflux family DUF3112 PF11309.3 KFM10609.1 - 0.11 12.2 6.2 0.037 13.8 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) AAA PF00004.24 KFM10610.1 - 6.2e-40 136.4 0.0 1.9e-39 134.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.13 KFM10610.1 - 4.5e-11 42.4 1.3 6.5e-11 41.9 0.2 1.9 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain RuvB_N PF05496.7 KFM10610.1 - 1.6e-06 27.3 0.1 7.2e-06 25.2 0.0 2.1 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KFM10610.1 - 2.8e-06 27.5 0.2 0.00092 19.3 0.1 3.5 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KFM10610.1 - 0.00015 21.4 0.2 0.0025 17.5 0.1 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 KFM10610.1 - 0.00038 19.2 0.1 0.001 17.8 0.0 1.6 1 1 1 2 2 2 1 TIP49 C-terminus AAA_2 PF07724.9 KFM10610.1 - 0.00095 19.1 0.0 0.0034 17.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 KFM10610.1 - 0.0013 19.5 0.0 0.003 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KFM10610.1 - 0.0018 17.4 0.4 0.0063 15.7 0.3 1.9 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI Vps4_C PF09336.5 KFM10610.1 - 0.004 17.0 0.0 0.0093 15.8 0.0 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain IstB_IS21 PF01695.12 KFM10610.1 - 0.0044 16.4 0.0 0.0097 15.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 KFM10610.1 - 0.0063 16.4 0.0 0.023 14.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KFM10610.1 - 0.0086 15.8 0.0 0.029 14.1 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KFM10610.1 - 0.012 15.5 0.7 0.14 12.1 0.1 2.7 1 1 1 3 3 3 0 AAA ATPase domain DUF815 PF05673.8 KFM10610.1 - 0.018 13.9 0.0 0.042 12.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.1 KFM10610.1 - 0.026 14.4 0.0 0.06 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.13 KFM10610.1 - 0.026 14.1 0.0 0.062 12.9 0.0 1.5 1 1 0 1 1 1 0 Bacterial dnaA protein AAA_25 PF13481.1 KFM10610.1 - 0.073 12.4 0.3 0.77 9.1 0.1 2.1 1 1 0 2 2 2 0 AAA domain DUF3549 PF12069.3 KFM10610.1 - 0.11 11.2 1.3 1.7 7.3 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3549) Dpy-30 PF05186.8 KFM10611.1 - 2.1e-09 36.6 0.6 3.2e-09 36.1 0.1 1.6 2 0 0 2 2 2 1 Dpy-30 motif Bmp PF02608.9 KFM10611.1 - 0.058 12.1 0.1 0.07 11.8 0.0 1.0 1 0 0 1 1 1 0 Basic membrane protein Memo PF01875.12 KFM10612.1 - 3.3e-76 255.8 0.0 4e-76 255.5 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Steroid_dh PF02544.11 KFM10613.1 - 6.4e-60 201.2 4.0 7.6e-60 201.0 2.8 1.1 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 KFM10613.1 - 2.9e-06 26.7 0.1 3.6e-06 26.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 KFM10613.1 - 5.2e-05 23.3 0.7 0.00011 22.2 0.5 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase zf-DHHC PF01529.15 KFM10613.1 - 0.049 13.0 0.1 0.088 12.2 0.1 1.4 1 1 0 1 1 1 0 DHHC palmitoyltransferase Acyl-CoA_dh_1 PF00441.19 KFM10614.1 - 7.9e-48 162.3 3.8 1.1e-47 161.8 2.6 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KFM10614.1 - 1.5e-27 96.4 0.1 2.8e-27 95.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KFM10614.1 - 2.2e-22 78.2 0.1 4.9e-22 77.1 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KFM10614.1 - 3.9e-21 75.6 2.1 6.2e-21 75.0 1.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain RUN PF02759.14 KFM10615.1 - 1.6e-41 141.1 0.0 4.9e-41 139.5 0.0 1.9 1 0 0 1 1 1 1 RUN domain RabGAP-TBC PF00566.13 KFM10615.1 - 1.2e-33 116.4 5.0 7.5e-32 110.5 2.5 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain SNF PF00209.13 KFM10616.1 - 4e-143 477.6 19.8 4.5e-143 477.4 13.8 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family GPCR_chapero_1 PF11904.3 KFM10617.1 - 4.7e-104 347.8 0.1 4.7e-104 347.8 0.0 1.9 2 0 0 2 2 2 1 GPCR-chaperone Ank_2 PF12796.2 KFM10617.1 - 6.3e-14 52.0 0.0 1.4e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFM10617.1 - 5.6e-13 47.9 0.0 4.2e-06 26.2 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KFM10617.1 - 2.8e-11 43.5 0.0 1e-10 41.8 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM10617.1 - 1e-10 41.5 0.0 9.3e-08 32.0 0.0 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM10617.1 - 3.9e-10 38.9 0.0 0.001 19.0 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat UIM PF02809.15 KFM10617.1 - 0.03 13.8 14.9 0.34 10.5 1.5 3.8 3 0 0 3 3 3 0 Ubiquitin interaction motif RNA_pol_Rbc25 PF08292.7 KFM10617.1 - 0.13 12.4 0.1 0.13 12.4 0.1 2.1 3 0 0 3 3 3 0 RNA polymerase III subunit Rpc25 GIT1_C PF12205.3 KFM10618.1 - 1.2e-60 202.7 3.9 3.3e-60 201.3 2.7 1.8 1 0 0 1 1 1 1 G protein-coupled receptor kinase-interacting protein 1 C term GIT_SHD PF08518.6 KFM10618.1 - 1.4e-31 107.4 2.0 2.4e-15 55.5 0.2 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT ArfGap PF01412.13 KFM10618.1 - 6.3e-22 77.5 0.0 6.3e-22 77.5 0.0 2.2 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf Ank_2 PF12796.2 KFM10618.1 - 3.8e-15 55.9 0.0 1.9e-14 53.7 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFM10618.1 - 5.9e-09 35.2 0.4 9.2e-05 22.0 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 KFM10618.1 - 1.6e-08 34.8 0.0 0.00017 22.0 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM10618.1 - 5.8e-08 32.7 0.1 4.1e-07 30.0 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM10618.1 - 0.0007 19.6 0.0 0.46 10.8 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat DUF4319 PF14203.1 KFM10618.1 - 0.014 14.9 0.1 0.071 12.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4319) Shugoshin_N PF07558.6 KFM10618.1 - 0.02 14.6 6.2 0.065 12.9 4.3 1.9 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region DUF3347 PF11827.3 KFM10618.1 - 0.45 10.4 6.1 1.5 8.7 4.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Trichoplein PF13868.1 KFM10619.1 - 2e-10 39.5 119.0 2.3e-10 39.4 82.5 1.0 1 0 0 1 1 1 1 Tumour suppressor, Mitostatin GLTP PF08718.6 KFM10620.1 - 5.4e-31 107.6 0.0 8.4e-31 107.0 0.0 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) GN3L_Grn1 PF08701.6 KFM10620.1 - 0.04 13.8 0.1 0.082 12.8 0.1 1.5 1 0 0 1 1 1 0 GNL3L/Grn1 putative GTPase Ank_2 PF12796.2 KFM10621.1 - 7.2e-15 55.0 0.1 2.3e-09 37.4 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFM10621.1 - 3e-14 51.9 0.1 1.6e-06 27.6 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 KFM10621.1 - 3.2e-12 45.4 0.1 0.00022 21.1 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 KFM10621.1 - 5.3e-12 45.5 0.2 0.0028 17.8 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ion_trans PF00520.26 KFM10621.1 - 8e-08 31.7 20.2 1.9e-07 30.5 14.0 1.7 1 1 0 1 1 1 1 Ion transport protein Ank_4 PF13637.1 KFM10621.1 - 1.1e-07 32.1 0.4 0.044 14.3 0.0 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) DUF4065 PF13274.1 KFM10621.1 - 0.031 14.9 0.0 0.067 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4065) Cob_adeno_trans PF01923.13 KFM10622.1 - 6.5e-45 152.8 0.0 7.6e-45 152.6 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase T2SF PF00482.18 KFM10622.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.4 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F HECT PF00632.20 KFM10623.1 - 2.4e-91 306.2 0.0 6e-91 304.8 0.0 1.7 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 KFM10623.1 - 0.00075 18.9 2.7 0.0027 17.2 1.9 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif BTB_2 PF02214.17 KFM10624.1 - 2.9e-20 72.2 0.0 5e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KFM10624.1 - 6e-05 22.9 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Myosin_TH1 PF06017.8 KFM10625.1 - 4.6e-35 120.7 2.0 5.3e-35 120.5 1.4 1.1 1 0 0 1 1 1 1 Myosin tail Fork_head PF00250.13 KFM10626.1 - 9.9e-31 105.6 0.5 1.8e-30 104.8 0.4 1.3 1 0 0 1 1 1 1 Fork head domain ACC_central PF08326.7 KFM10627.1 - 9.9e-237 787.5 4.7 1.3e-236 787.1 3.3 1.2 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 KFM10627.1 - 6.8e-172 572.2 0.0 9.1e-172 571.8 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 KFM10627.1 - 1.7e-51 174.5 0.1 3.6e-51 173.4 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 KFM10627.1 - 1.5e-22 79.5 0.0 4.4e-22 78.0 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 KFM10627.1 - 5.2e-17 61.9 0.0 1.8e-16 60.2 0.0 2.0 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_lipoyl PF00364.17 KFM10627.1 - 7.5e-12 44.7 0.0 1.9e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 KFM10627.1 - 3.1e-11 43.3 0.1 7.9e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KFM10627.1 - 6.4e-08 31.7 0.0 1.2e-05 24.2 0.0 3.2 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KFM10627.1 - 5e-05 22.7 0.0 0.00011 21.6 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KFM10627.1 - 0.00051 19.4 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KFM10627.1 - 0.0017 18.2 0.0 0.0045 16.8 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain UPF0150 PF03681.10 KFM10627.1 - 0.11 12.1 0.0 0.28 10.8 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0150) UDG PF03167.14 KFM10628.1 - 1.4e-28 99.2 0.0 1.6e-28 99.1 0.0 1.0 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily 2OG-FeII_Oxy_2 PF13532.1 KFM10629.1 - 2.9e-28 99.0 0.0 3.2e-28 98.8 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KFM10629.1 - 1.1e-05 25.6 0.0 1.6e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sugar_tr PF00083.19 KFM10630.1 - 2.4e-38 131.8 28.9 1e-25 90.2 7.6 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KFM10630.1 - 6.9e-36 123.6 38.6 2.7e-21 75.6 15.2 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFM10630.1 - 0.041 12.2 23.1 0.025 13.0 0.5 3.8 3 1 1 4 4 4 0 MFS/sugar transport protein DAO PF01266.19 KFM10631.1 - 2e-28 99.3 0.0 6.5e-28 97.6 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 KFM10631.1 - 0.015 14.6 0.1 0.029 13.7 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.22 KFM10631.1 - 0.1 13.0 0.2 0.72 10.2 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DSPc PF00782.15 KFM10632.1 - 1.6e-36 124.7 0.0 3.5e-36 123.7 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DEK_C PF08766.6 KFM10632.1 - 6.7e-17 61.0 5.1 1.3e-16 60.0 1.3 2.5 2 0 0 2 2 2 1 DEK C terminal domain Y_phosphatase PF00102.22 KFM10632.1 - 0.0042 16.4 0.0 0.0097 15.2 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF1900 PF08954.6 KFM10633.1 - 4.3e-58 194.6 0.0 1.3e-57 193.1 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 KFM10633.1 - 4.2e-35 119.2 0.1 7.7e-35 118.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 KFM10633.1 - 4.6e-24 83.3 6.9 1.3e-09 37.5 0.4 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat eIF2A PF08662.6 KFM10633.1 - 0.0076 15.9 0.0 0.024 14.3 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A DUF4094 PF13334.1 KFM10633.1 - 0.48 10.8 3.1 1.2 9.5 2.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) NifU_N PF01592.11 KFM10634.1 - 7.4e-52 174.5 0.1 8.5e-52 174.4 0.1 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain Jag_N PF14804.1 KFM10634.1 - 0.026 14.5 0.4 4.6 7.3 0.0 2.5 2 0 0 2 2 2 0 Jag N-terminus Proteasome PF00227.21 KFM10634.1 - 0.06 12.6 0.1 0.11 11.8 0.0 1.4 2 0 0 2 2 2 0 Proteasome subunit CO_deh_flav_C PF03450.12 KFM10634.1 - 0.11 12.4 0.2 0.82 9.6 0.0 2.0 1 1 1 2 2 2 0 CO dehydrogenase flavoprotein C-terminal domain RRM_1 PF00076.17 KFM10635.1 - 3.2e-33 113.1 0.1 4.4e-17 61.4 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM10635.1 - 4.6e-24 84.1 0.0 4.2e-12 45.8 0.0 3.8 4 0 0 4 4 4 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM10635.1 - 1.5e-13 50.3 0.1 1.9e-05 24.3 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lsm_interact PF05391.6 KFM10635.1 - 1.1e-05 24.6 1.3 3e-05 23.2 0.9 1.8 1 0 0 1 1 1 1 Lsm interaction motif DUF1993 PF09351.5 KFM10635.1 - 0.015 15.2 3.5 7.1 6.5 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1993) DUF1866 PF08952.6 KFM10635.1 - 0.031 13.8 0.0 10 5.6 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1866) RNase_H2-Ydr279 PF09468.5 KFM10635.1 - 0.092 11.9 4.5 0.2 10.8 3.1 1.6 1 1 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Nup35_RRM_2 PF14605.1 KFM10635.1 - 0.11 12.2 0.0 15 5.4 0.0 2.8 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF908 PF06012.7 KFM10635.1 - 0.15 11.3 4.9 2.5 7.3 1.8 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) TPR_14 PF13428.1 KFM10635.1 - 0.74 10.6 12.9 21 6.0 0.2 6.5 7 1 1 8 8 8 0 Tetratricopeptide repeat Fic PF02661.13 KFM10636.1 - 2.2e-28 98.7 0.0 4.5e-28 97.7 0.0 1.5 1 0 0 1 1 1 1 Fic/DOC family TPR_11 PF13414.1 KFM10636.1 - 0.00084 18.9 1.2 0.0019 17.8 0.5 1.8 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 KFM10636.1 - 0.0015 18.3 1.0 0.018 14.9 0.3 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFM10636.1 - 0.031 14.9 0.2 0.08 13.6 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat T6SS-SciN PF12790.2 KFM10636.1 - 0.15 11.6 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Type VI secretion lipoprotein TPR_12 PF13424.1 KFM10636.1 - 0.18 11.7 1.0 1.4 8.9 0.7 2.3 1 1 0 1 1 1 0 Tetratricopeptide repeat 7tm_1 PF00001.16 KFM10637.1 - 2e-52 177.9 27.1 2.4e-52 177.6 18.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) WSC PF01822.14 KFM10638.1 - 1.5e-32 111.3 19.2 3.7e-20 71.6 6.9 2.2 2 0 0 2 2 2 2 WSC domain Sulfotransfer_1 PF00685.22 KFM10638.1 - 2.5e-05 23.6 0.0 6.9e-05 22.2 0.0 1.6 1 1 1 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 KFM10638.1 - 0.0077 17.1 0.1 0.012 16.5 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family C2 PF00168.25 KFM10639.1 - 3e-43 145.5 0.0 2.8e-21 75.1 0.0 2.3 2 0 0 2 2 2 2 C2 domain FYVE_2 PF02318.11 KFM10639.1 - 1.5e-35 121.6 9.0 2.7e-35 120.7 5.5 1.9 2 0 0 2 2 2 1 FYVE-type zinc finger zf-piccolo PF05715.8 KFM10639.1 - 0.03 14.3 10.1 0.21 11.6 6.2 2.4 2 0 0 2 2 2 0 Piccolo Zn-finger C1_1 PF00130.17 KFM10639.1 - 2.1 8.1 12.6 0.25 11.1 5.0 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Y_phosphatase PF00102.22 KFM10640.1 - 4.2e-79 265.1 0.5 5.5e-79 264.8 0.3 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFM10640.1 - 5.3e-06 26.0 0.1 2.5e-05 23.8 0.0 2.2 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 KFM10640.1 - 0.00041 20.4 0.5 0.0014 18.6 0.0 2.0 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 KFM10640.1 - 0.0014 18.9 0.1 0.0093 16.2 0.0 2.2 2 0 0 2 2 2 1 Tyrosine phosphatase family DUF1092 PF06485.6 KFM10640.1 - 0.018 14.0 0.1 0.031 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1092) SH2 PF00017.19 KFM10641.1 - 7e-25 86.6 0.0 8.8e-25 86.3 0.0 1.1 1 0 0 1 1 1 1 SH2 domain Ribosomal_L6e PF01159.14 KFM10642.1 - 5.3e-41 139.2 1.0 5.3e-41 139.2 0.7 2.6 3 0 0 3 3 3 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.10 KFM10642.1 - 6.9e-24 83.5 12.5 6.9e-24 83.5 8.7 3.3 3 0 0 3 3 3 1 Ribosomal protein L6, N-terminal domain HC2 PF07382.6 KFM10642.1 - 0.84 9.4 23.0 1.9 8.3 15.9 1.6 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 HECT PF00632.20 KFM10644.1 - 1.8e-48 165.3 0.0 3.6e-48 164.3 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Vps35 PF03635.12 KFM10644.1 - 0.22 9.6 0.0 0.37 8.8 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 35 NatB_MDM20 PF09797.4 KFM10645.1 - 6.2e-108 360.7 2.7 6.2e-108 360.7 1.9 1.9 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_14 PF13428.1 KFM10645.1 - 9.9e-06 25.7 4.0 0.91 10.3 0.0 6.2 4 2 3 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFM10645.1 - 1.2e-05 25.8 2.7 0.014 16.0 0.2 4.2 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFM10645.1 - 0.0021 18.3 8.4 0.43 10.9 0.3 4.4 4 1 1 5 5 5 2 Tetratricopeptide repeat BTAD PF03704.12 KFM10645.1 - 0.0099 16.1 0.6 0.17 12.1 0.3 2.8 2 1 1 3 3 3 1 Bacterial transcriptional activator domain DUF3510 PF12022.3 KFM10645.1 - 0.2 11.7 3.5 0.43 10.6 0.5 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3510) TPR_11 PF13414.1 KFM10645.1 - 0.38 10.4 11.1 1.9 8.2 0.1 4.5 4 1 2 6 6 6 0 TPR repeat TPR_2 PF07719.12 KFM10645.1 - 0.75 9.8 6.7 12 6.1 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat ERp29_N PF07912.8 KFM10646.1 - 2.6e-43 146.9 0.2 4e-43 146.3 0.1 1.3 1 0 0 1 1 1 1 ERp29, N-terminal domain ERp29 PF07749.7 KFM10646.1 - 3.6e-16 59.5 4.4 3.6e-16 59.5 3.0 1.5 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain PRTase_1 PF11202.3 KFM10646.1 - 0.0022 16.9 1.9 0.0035 16.3 1.3 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase (PRTase) Git3_C PF11970.3 KFM10647.1 - 0.00025 20.7 1.9 0.00071 19.2 1.3 1.7 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.16 KFM10647.1 - 0.041 13.0 10.4 0.026 13.6 4.7 2.0 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) Pkinase PF00069.20 KFM10648.1 - 6.3e-62 209.0 0.0 1.4e-61 207.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM10648.1 - 2.6e-22 79.1 0.1 1.4e-21 76.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM10648.1 - 8.8e-06 24.8 0.0 2e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFM10648.1 - 0.00023 20.3 0.2 0.00043 19.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KFM10648.1 - 0.045 13.3 0.1 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase NTP_transf_4 PF13562.1 KFM10648.1 - 0.048 13.3 0.3 0.62 9.6 0.2 2.3 1 1 0 1 1 1 0 Sugar nucleotidyl transferase APH PF01636.18 KFM10648.1 - 0.1 12.2 0.3 0.4 10.3 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Aldedh PF00171.17 KFM10649.1 - 3.2e-190 632.3 0.0 3.6e-190 632.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KFM10649.1 - 0.035 12.8 0.0 0.062 12.0 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) APH PF01636.18 KFM10650.1 - 1.9e-40 139.1 0.2 2.8e-40 138.5 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family HAD_2 PF13419.1 KFM10650.1 - 1.4e-14 54.6 0.0 2.4e-13 50.6 0.0 2.6 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFM10650.1 - 0.00045 20.7 0.0 0.0025 18.2 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase EcKinase PF02958.15 KFM10650.1 - 0.00058 19.0 0.0 0.001 18.2 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase Kdo PF06293.9 KFM10650.1 - 0.00066 18.8 0.0 0.0013 17.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Hydrolase_like PF13242.1 KFM10650.1 - 0.0045 16.6 0.0 0.0095 15.6 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like RIO1 PF01163.17 KFM10650.1 - 0.0056 16.0 0.0 0.14 11.4 0.0 2.4 1 1 0 2 2 2 1 RIO1 family Acid_PPase PF12689.2 KFM10650.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Acid Phosphatase BRAP2 PF07576.7 KFM10651.1 - 3.8e-41 139.0 1.1 7.7e-41 138.1 0.7 1.5 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 KFM10651.1 - 3.4e-20 71.9 8.8 3.4e-20 71.9 6.1 2.3 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 KFM10651.1 - 1.1e-09 37.9 7.0 1.1e-09 37.9 4.9 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KFM10651.1 - 1.3e-06 28.0 5.6 1.3e-06 28.0 3.9 2.7 2 0 0 2 2 2 1 zinc-RING finger domain RRM_6 PF14259.1 KFM10651.1 - 4.3e-05 23.4 0.0 0.00012 22.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4 PF00097.20 KFM10651.1 - 5.8e-05 22.6 6.2 5.8e-05 22.6 4.3 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFM10651.1 - 7.2e-05 22.8 5.7 7.2e-05 22.8 3.9 2.7 2 1 0 2 2 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KFM10651.1 - 8e-05 22.5 5.6 8e-05 22.5 3.9 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM10651.1 - 0.00014 21.4 17.7 0.0004 19.9 5.3 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.17 KFM10651.1 - 0.00065 19.2 0.0 0.0014 18.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-Apc11 PF12861.2 KFM10651.1 - 0.0037 17.0 3.1 0.016 15.0 2.1 2.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_PEP_C PF04513.7 KFM10651.1 - 0.12 12.1 8.8 0.13 12.1 4.4 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Vac_Fusion PF02346.11 KFM10651.1 - 0.19 11.1 3.7 0.55 9.6 0.7 2.8 1 1 1 2 2 2 0 Chordopoxvirus fusion protein Sec34 PF04136.10 KFM10651.1 - 0.27 10.9 13.6 0.57 9.8 9.4 1.4 1 0 0 1 1 1 0 Sec34-like family GBP_C PF02841.9 KFM10651.1 - 0.29 10.2 22.8 0.11 11.6 13.0 2.0 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain Adenylsucc_synt PF00709.16 KFM10651.1 - 0.29 9.7 5.4 0.44 9.1 3.7 1.2 1 0 0 1 1 1 0 Adenylosuccinate synthetase DUF342 PF03961.8 KFM10651.1 - 0.37 9.1 15.0 0.56 8.5 10.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2317 PF10079.4 KFM10651.1 - 0.71 8.4 14.4 1.2 7.7 10.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) NPV_P10 PF05531.7 KFM10651.1 - 0.81 9.9 8.2 6.7 7.0 4.0 3.2 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein PulS_OutS PF09691.5 KFM10651.1 - 1.2 9.1 9.8 0.33 10.9 1.6 3.3 1 1 3 4 4 4 0 Bacterial chaperone lipoprotein (PulS_OutS) DUF972 PF06156.8 KFM10651.1 - 2.8 8.3 18.4 0.6 10.4 5.4 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) zf-RING_6 PF14835.1 KFM10651.1 - 4.4 7.1 11.3 0.53 10.0 4.2 2.2 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-ribbon_3 PF13248.1 KFM10651.1 - 5.2 6.4 8.8 4.7 6.5 4.4 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Phe_ZIP PF08916.6 KFM10652.1 - 5.2e-21 74.7 6.0 5.2e-21 74.7 4.2 1.8 2 0 0 2 2 2 1 Phenylalanine zipper PH PF00169.24 KFM10652.1 - 7.7e-06 26.0 0.0 1.2e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 PH domain EF-hand_1 PF00036.27 KFM10653.1 - 9.6e-13 46.4 3.3 5.1e-06 25.4 0.6 4.1 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 KFM10653.1 - 5.9e-11 41.8 2.5 0.00058 19.4 0.0 3.7 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_7 PF13499.1 KFM10653.1 - 1.1e-10 41.5 0.7 1.4e-06 28.3 0.1 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 KFM10653.1 - 5.8e-09 35.1 1.2 2.9e-06 26.7 0.5 3.3 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 KFM10653.1 - 4.6e-05 22.5 3.0 0.00032 19.8 1.1 2.9 3 0 0 3 3 3 1 EF hand mTERF PF02536.9 KFM10653.1 - 0.14 10.7 0.0 0.18 10.3 0.0 1.2 1 0 0 1 1 1 0 mTERF Pox_A_type_inc PF04508.7 KFM10654.1 - 0.047 13.4 0.4 0.047 13.4 0.3 5.5 7 0 0 7 7 7 0 Viral A-type inclusion protein repeat FlaC_arch PF05377.6 KFM10654.1 - 0.048 13.5 0.8 0.048 13.5 0.6 4.5 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) RimM PF01782.13 KFM10654.1 - 0.22 11.4 2.2 11 6.0 0.1 2.7 2 0 0 2 2 2 0 RimM N-terminal domain DUF948 PF06103.6 KFM10654.1 - 4.6 7.1 23.2 5.7 6.8 2.6 5.1 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.5 KFM10654.1 - 7.6 6.6 34.2 0.79 9.8 1.0 3.5 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Metallophos PF00149.23 KFM10655.1 - 1.9e-44 151.4 0.4 2.2e-44 151.2 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ion_trans PF00520.26 KFM10656.1 - 5.9e-05 22.4 7.2 5.9e-05 22.4 5.0 1.5 2 0 0 2 2 2 1 Ion transport protein MVIN PF03023.9 KFM10656.1 - 0.046 12.1 3.1 0.055 11.8 2.2 1.1 1 0 0 1 1 1 0 MviN-like protein ERp29 PF07749.7 KFM10656.1 - 0.053 14.1 0.4 0.1 13.2 0.3 1.5 1 0 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain DUF1619 PF07773.6 KFM10657.1 - 7.3e-68 229.5 5.3 7.3e-68 229.5 3.7 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1619) SpoIIE PF07228.7 KFM10658.1 - 6.4e-15 55.3 0.0 1e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 KFM10658.1 - 9.7e-07 28.3 0.1 2.8e-06 26.9 0.1 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 KFM10658.1 - 2e-05 24.0 0.2 0.0057 16.0 0.1 2.4 2 1 0 2 2 2 2 Protein phosphatase 2C Metallophos_2 PF12850.2 KFM10659.1 - 4.5e-21 75.3 0.1 5.1e-21 75.1 0.1 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KFM10659.1 - 2.2e-07 30.5 1.9 0.00031 20.2 1.3 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase SMAP PF15477.1 KFM10660.1 - 4.2e-13 49.3 0.9 4.2e-13 49.3 0.6 4.6 4 1 0 4 4 4 1 Small acidic protein family DUF1777 PF08648.7 KFM10660.1 - 0.00039 20.2 52.8 0.00039 20.2 36.6 4.1 2 1 2 4 4 4 1 Protein of unknown function (DUF1777) SR-25 PF10500.4 KFM10660.1 - 0.0015 18.0 32.3 0.0015 18.0 22.4 3.9 3 1 1 4 4 4 1 Nuclear RNA-splicing-associated protein Pap_E4 PF02711.9 KFM10660.1 - 0.17 12.7 0.2 0.17 12.7 0.1 5.5 1 1 1 2 2 2 0 E4 protein CAP_GLY PF01302.20 KFM10661.1 - 1.2e-47 159.4 3.3 4.3e-24 83.9 0.2 2.3 2 0 0 2 2 2 2 CAP-Gly domain IncA PF04156.9 KFM10661.1 - 0.00069 19.2 31.6 0.00069 19.2 21.9 10.6 1 1 9 10 10 10 4 IncA protein zf-CCHC_4 PF14392.1 KFM10661.1 - 3.2 7.5 10.0 12 5.6 0.3 2.9 2 0 0 2 2 2 0 Zinc knuckle Sec1 PF00995.18 KFM10662.1 - 6.3e-119 398.1 0.0 7e-119 398.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Smac_DIABLO PF09057.5 KFM10663.1 - 1e-93 312.7 8.2 1.1e-93 312.6 5.7 1.0 1 0 0 1 1 1 1 Second Mitochondria-derived Activator of Caspases TraD_N PF12615.3 KFM10663.1 - 0.035 14.4 1.1 0.074 13.3 0.5 1.8 2 1 0 2 2 2 0 F sex factor protein N terminal Metalloenzyme PF01676.13 KFM10663.1 - 0.11 11.9 0.1 0.22 10.8 0.0 1.6 2 0 0 2 2 2 0 Metalloenzyme superfamily LRR_4 PF12799.2 KFM10664.1 - 4.5e-13 48.4 14.1 4.5e-07 29.3 2.6 4.1 2 2 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM10664.1 - 9.8e-11 41.2 8.9 3.4e-05 23.5 0.2 3.4 3 1 1 4 4 4 3 Leucine rich repeat LRR_6 PF13516.1 KFM10664.1 - 3.7e-07 29.5 10.3 0.052 13.6 0.8 5.9 5 2 1 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.28 KFM10664.1 - 5.8e-06 25.6 12.4 0.58 10.3 0.9 5.9 5 1 0 5 5 5 3 Leucine Rich Repeat LRR_9 PF14580.1 KFM10664.1 - 1.8e-05 24.3 0.7 0.0019 17.7 0.0 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_7 PF13504.1 KFM10664.1 - 0.002 18.0 12.2 1.9 9.0 0.3 6.0 6 0 0 6 6 6 1 Leucine rich repeat HLH PF00010.21 KFM10665.1 - 1.2e-06 28.0 0.9 1.2e-06 28.0 0.6 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Troponin PF00992.15 KFM10665.1 - 0.0089 16.0 0.5 0.016 15.2 0.4 1.4 1 0 0 1 1 1 1 Troponin DUF904 PF06005.7 KFM10665.1 - 0.013 15.7 1.4 0.034 14.4 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DivIC PF04977.10 KFM10665.1 - 0.085 12.3 2.5 0.17 11.3 1.7 1.4 1 0 0 1 1 1 0 Septum formation initiator RVT_connect PF06815.8 KFM10665.1 - 0.23 11.3 2.8 0.24 11.2 0.4 2.1 2 0 0 2 2 2 0 Reverse transcriptase connection domain Seryl_tRNA_N PF02403.17 KFM10665.1 - 0.27 11.2 2.9 0.57 10.2 2.0 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF342 PF03961.8 KFM10665.1 - 0.34 9.2 1.0 0.52 8.6 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) BCL_N PF04714.8 KFM10666.1 - 8e-09 34.9 1.5 1.8e-08 33.7 0.6 1.9 2 0 0 2 2 2 1 BCL7, N-terminal conserver region Defensin_propep PF00879.13 KFM10666.1 - 0.11 12.4 1.3 0.3 11.0 0.9 1.7 1 0 0 1 1 1 0 Defensin propeptide WD40 PF00400.27 KFM10667.1 - 2.3e-25 87.5 8.5 0.0011 18.7 0.1 8.9 9 0 0 9 9 9 6 WD domain, G-beta repeat EF-hand_7 PF13499.1 KFM10667.1 - 0.0089 16.1 0.0 0.49 10.5 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair PDZ_2 PF13180.1 KFM10668.1 - 3.9e-10 39.4 0.0 5.5e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 KFM10668.1 - 3.7e-07 30.2 0.1 5.4e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) GRASP55_65 PF04495.9 KFM10668.1 - 6.6e-06 26.1 0.0 7.5e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain RdgC PF04381.7 KFM10668.1 - 0.094 11.6 1.4 0.16 10.8 0.9 1.3 1 0 0 1 1 1 0 Putative exonuclease, RdgC THOC7 PF05615.8 KFM10668.1 - 0.36 11.1 2.6 0.48 10.6 1.8 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 Glyoxalase PF00903.20 KFM10669.1 - 3.3e-23 82.0 0.7 2.2e-14 53.5 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 KFM10669.1 - 5.7e-13 48.8 0.1 6.4e-07 29.3 0.1 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KFM10669.1 - 1.3e-07 32.1 0.0 7.3e-05 23.3 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 KFM10669.1 - 0.00072 19.5 0.2 0.002 18.0 0.1 1.7 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.1 KFM10669.1 - 0.0029 17.5 0.0 2.7 7.8 0.0 2.9 3 0 0 3 3 3 2 Glyoxalase-like domain N-SET PF11764.3 KFM10670.1 - 5.5e-37 127.2 0.0 5.5e-37 127.2 0.0 3.1 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.23 KFM10670.1 - 6e-22 78.6 1.8 6e-22 78.6 1.2 4.0 3 2 0 3 3 3 1 SET domain RRM_1 PF00076.17 KFM10670.1 - 5.4e-09 35.5 0.1 1.3e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM10670.1 - 3.2e-06 26.8 0.0 6.8e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM10670.1 - 3.3e-06 26.9 0.1 6.4e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.17 KFM10671.1 - 1.4e-38 131.8 0.1 1.7e-38 131.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM10671.1 - 2.3e-09 37.7 0.0 4.5e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM10671.1 - 0.00066 18.9 0.0 0.00094 18.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFM10671.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain GTSE1_N PF15259.1 KFM10671.1 - 0.14 12.1 0.9 0.2 11.5 0.6 1.3 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 TMPIT PF07851.8 KFM10672.1 - 4.4e-159 528.8 15.9 5e-159 528.6 11.1 1.0 1 0 0 1 1 1 1 TMPIT-like protein ALIX_LYPXL_bnd PF13949.1 KFM10672.1 - 0.16 10.9 1.9 0.24 10.3 1.3 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Snapin_Pallidin PF14712.1 KFM10672.1 - 1.7 9.0 4.7 1.7 8.9 0.6 2.3 2 0 0 2 2 2 0 Snapin/Pallidin MORN PF02493.15 KFM10673.1 - 4.3e-24 82.7 39.6 3e-05 23.4 0.2 6.9 7 0 0 7 7 7 6 MORN repeat Orai-1 PF07856.7 KFM10674.1 - 7.2e-60 201.5 4.1 8.1e-60 201.3 2.8 1.0 1 0 0 1 1 1 1 Mediator of CRAC channel activity 7tm_3 PF00003.17 KFM10674.1 - 0.024 13.9 2.9 0.038 13.3 2.0 1.3 1 1 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR KASH PF10541.4 KFM10674.1 - 0.041 13.7 0.9 0.54 10.1 0.1 2.3 2 0 0 2 2 2 0 Nuclear envelope localisation domain DctQ PF04290.7 KFM10674.1 - 0.056 13.2 0.5 0.056 13.2 0.4 1.8 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component 7TM_GPCR_Str PF10326.4 KFM10674.1 - 0.058 12.5 4.6 1.5 7.8 0.3 2.0 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Str m04gp34like PF12216.3 KFM10674.1 - 0.067 12.5 0.3 0.84 8.9 0.0 2.0 1 1 1 2 2 2 0 Immune evasion protein Ycf4 PF02392.11 KFM10674.1 - 0.23 10.7 0.9 13 5.0 0.1 2.2 2 1 0 2 2 2 0 Ycf4 DUF1282 PF06930.7 KFM10674.1 - 0.26 10.9 3.4 0.16 11.5 0.3 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1282) DUF4328 PF14219.1 KFM10674.1 - 0.46 9.7 3.7 2.3 7.4 0.2 2.7 2 1 0 3 3 3 0 Domain of unknown function (DUF4328) Neurensin PF14927.1 KFM10674.1 - 1.2 8.5 4.1 4.8 6.5 1.6 2.3 1 1 1 2 2 2 0 Neurensin zf-CXXC PF02008.15 KFM10675.1 - 1.2e-14 53.8 21.5 1.2e-14 53.8 14.9 3.1 2 0 0 2 2 2 1 CXXC zinc finger domain F-box PF00646.28 KFM10675.1 - 2.4e-13 49.3 6.9 1.3e-12 46.9 1.1 2.8 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KFM10675.1 - 4.1e-09 36.0 6.1 1.2e-08 34.5 4.2 1.8 1 0 0 1 1 1 1 F-box-like Cupin_8 PF13621.1 KFM10675.1 - 2.1e-06 27.4 0.0 2.1e-06 27.4 0.0 2.4 3 1 0 3 3 3 1 Cupin-like domain LRR_8 PF13855.1 KFM10675.1 - 1.1e-05 25.0 7.5 0.25 11.1 0.2 4.4 4 0 0 4 4 4 3 Leucine rich repeat JmjC PF02373.17 KFM10675.1 - 5.4e-05 23.4 0.3 5.4e-05 23.4 0.2 3.4 3 1 0 3 3 3 1 JmjC domain, hydroxylase LRR_6 PF13516.1 KFM10675.1 - 0.00076 19.3 16.1 0.91 9.7 0.0 7.0 8 1 0 8 8 8 2 Leucine Rich repeat LRR_1 PF00560.28 KFM10675.1 - 6.2 7.2 12.6 27 5.3 0.1 6.1 6 1 0 6 6 6 0 Leucine Rich Repeat Apc5 PF12862.2 KFM10676.1 - 6e-31 106.1 10.5 9.1e-31 105.5 1.2 4.3 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.1 KFM10676.1 - 1.3e-07 31.4 14.0 0.0024 17.7 0.1 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFM10676.1 - 1.8e-05 24.9 14.0 0.0076 16.5 0.1 5.3 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFM10676.1 - 3.9e-05 23.1 6.4 0.046 13.5 0.5 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 KFM10676.1 - 0.00015 21.6 5.9 0.32 10.9 1.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFM10676.1 - 0.0072 16.8 16.3 0.22 12.2 0.4 7.1 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFM10676.1 - 0.023 14.5 12.3 7.3 6.7 0.0 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_21 PF09976.4 KFM10676.1 - 0.029 14.3 4.0 1.7 8.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFM10676.1 - 0.031 13.8 4.8 2 8.1 0.9 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 KFM10676.1 - 0.16 11.5 12.7 0.42 10.3 0.3 4.8 4 1 1 5 5 5 0 TPR repeat TPR_16 PF13432.1 KFM10676.1 - 0.39 11.4 13.5 9.8 6.9 1.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 KFM10676.1 - 10 6.8 11.1 73 4.1 0.0 5.8 6 1 0 6 6 6 0 Tetratricopeptide repeat Pkinase PF00069.20 KFM10677.1 - 3.5e-66 222.9 0.0 5.2e-66 222.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM10677.1 - 3e-34 118.2 0.0 5.5e-32 110.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KFM10677.1 - 1.1e-09 37.6 0.0 1.8e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KFM10677.1 - 0.01 15.2 0.1 0.017 14.4 0.1 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 KFM10677.1 - 0.014 15.1 0.2 0.53 9.9 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KFM10677.1 - 0.15 10.8 0.4 1.7 7.3 0.0 2.2 2 0 0 2 2 2 0 Seadornavirus VP7 P2X_receptor PF00864.14 KFM10678.1 - 6.7e-157 521.9 5.2 7.5e-157 521.8 3.6 1.0 1 0 0 1 1 1 1 ATP P2X receptor DUF4200 PF13863.1 KFM10679.1 - 0.00033 20.5 5.6 0.00033 20.5 3.9 7.1 3 2 4 7 7 7 1 Domain of unknown function (DUF4200) DUF948 PF06103.6 KFM10679.1 - 0.044 13.6 0.5 0.044 13.6 0.4 5.2 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) MSG PF02349.10 KFM10679.1 - 0.58 10.1 16.4 5.6 7.0 0.5 3.7 2 1 0 2 2 2 0 Major surface glycoprotein Reo_sigmaC PF04582.7 KFM10679.1 - 1.6 7.8 7.4 1.1 8.4 0.1 3.0 2 1 0 3 3 3 0 Reovirus sigma C capsid protein NPBW PF15180.1 KFM10679.1 - 6.1 6.5 7.9 0.33 10.6 0.1 2.9 3 1 0 3 3 3 0 Neuropeptides B and W NPV_P10 PF05531.7 KFM10679.1 - 7.8 6.8 16.3 11 6.3 0.3 5.4 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein E1-E2_ATPase PF00122.15 KFM10680.1 - 1e-68 230.7 2.9 1.5e-66 223.7 1.3 2.6 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFM10680.1 - 9.9e-45 152.2 3.1 9.9e-45 152.2 2.1 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFM10680.1 - 3.2e-29 102.8 0.1 7.2e-23 82.1 0.0 2.8 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFM10680.1 - 1e-22 79.9 0.4 2.3e-22 78.7 0.3 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KFM10680.1 - 5.1e-18 64.3 1.2 3.9e-17 61.4 0.1 2.6 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KFM10680.1 - 1.8e-14 54.3 0.7 7.8e-14 52.2 0.5 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFM10680.1 - 2.2e-05 24.1 0.6 2.2e-05 24.1 0.4 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase TPR_11 PF13414.1 KFM10681.1 - 1.2e-24 85.7 13.3 3.1e-08 33.1 0.1 7.0 4 2 1 6 6 6 5 TPR repeat TPR_2 PF07719.12 KFM10681.1 - 4.5e-20 69.8 17.0 5.3e-05 22.8 0.0 9.6 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 KFM10681.1 - 8.9e-19 67.6 2.5 0.00051 20.6 0.1 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFM10681.1 - 1.7e-16 59.2 11.2 0.0087 16.6 0.1 8.9 5 4 5 10 10 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFM10681.1 - 1.7e-16 60.2 13.9 7.8e-05 22.9 0.0 6.6 3 2 2 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.23 KFM10681.1 - 1.9e-13 49.3 15.8 0.00012 21.5 0.0 8.7 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFM10681.1 - 3.3e-10 38.9 2.7 0.013 15.1 0.0 5.8 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFM10681.1 - 7.6e-10 38.5 19.9 0.024 14.5 0.5 7.7 4 2 3 7 7 7 5 Tetratricopeptide repeat Apc3 PF12895.2 KFM10681.1 - 1.5e-08 34.6 21.8 0.084 13.0 0.4 6.4 4 3 2 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 KFM10681.1 - 2.9e-07 30.1 11.6 0.022 14.9 0.0 8.1 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFM10681.1 - 5.4e-07 28.9 8.0 0.49 10.3 0.0 6.8 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFM10681.1 - 1e-06 28.7 12.5 1.7 9.2 0.0 7.3 8 0 0 8 8 8 3 Tetratricopeptide repeat ChAPs PF09295.5 KFM10681.1 - 1.6e-05 23.8 3.4 0.23 10.1 0.1 3.3 2 1 1 3 3 3 3 ChAPs (Chs5p-Arf1p-binding proteins) TPR_21 PF09976.4 KFM10681.1 - 7.4e-05 22.7 8.7 0.00022 21.2 1.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFM10681.1 - 0.0073 16.1 2.4 1.3 8.8 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_5 PF12688.2 KFM10681.1 - 0.0077 16.2 4.0 0.19 11.7 0.5 3.7 3 1 2 5 5 5 1 Tetratrico peptide repeat NARP1 PF12569.3 KFM10681.1 - 0.011 14.5 10.4 5.2 5.7 0.4 4.4 3 1 2 5 5 5 0 NMDA receptor-regulated protein 1 TPR_20 PF14561.1 KFM10681.1 - 0.13 12.3 8.6 4 7.6 0.2 5.4 5 2 1 6 6 6 0 Tetratricopeptide repeat BTAD PF03704.12 KFM10681.1 - 0.23 11.7 2.6 0.35 11.1 0.4 2.3 2 1 1 3 3 3 0 Bacterial transcriptional activator domain P21-Arc PF04062.9 KFM10682.1 - 1.8e-80 268.8 0.1 2e-80 268.6 0.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit ATP_bind_1 PF03029.12 KFM10683.1 - 4.3e-84 281.7 0.8 4.9e-84 281.5 0.6 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein SUI1 PF01253.17 KFM10684.1 - 2.9e-17 62.2 0.2 5.2e-17 61.4 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 TMF_TATA_bd PF12325.3 KFM10685.1 - 0.00048 19.8 11.6 0.00048 19.8 8.0 3.9 1 1 2 3 3 3 1 TATA element modulatory factor 1 TATA binding Nup54 PF13874.1 KFM10685.1 - 0.0038 16.8 9.4 0.0038 16.8 6.5 3.3 1 1 2 3 3 3 1 Nucleoporin complex subunit 54 BRX_N PF13713.1 KFM10685.1 - 0.0068 15.8 0.6 0.12 11.9 0.1 3.1 3 0 0 3 3 3 1 Transcription factor BRX N-terminal domain DUF4179 PF13786.1 KFM10685.1 - 0.24 11.6 0.1 0.24 11.6 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4179) Atg14 PF10186.4 KFM10685.1 - 0.6 9.0 42.2 0.83 8.5 10.1 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 CobA_CobO_BtuR PF02572.10 KFM10685.1 - 0.77 9.3 7.9 0.23 11.0 1.6 2.5 2 1 1 3 3 3 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP CALCOCO1 PF07888.6 KFM10685.1 - 1.4 7.1 36.9 0.62 8.2 14.4 2.1 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Reo_sigmaC PF04582.7 KFM10685.1 - 1.5 7.9 9.7 0.6 9.2 3.7 2.2 1 1 2 3 3 3 0 Reovirus sigma C capsid protein DUF4201 PF13870.1 KFM10685.1 - 1.6 8.1 53.5 0.11 11.8 9.3 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) Y_phosphatase PF00102.22 KFM10685.1 - 1.8 7.8 7.2 0.27 10.5 0.7 2.3 1 1 2 3 3 3 0 Protein-tyrosine phosphatase ANTH PF07651.11 KFM10686.1 - 6.9e-74 248.0 8.2 9.8e-74 247.5 0.0 2.6 2 0 0 2 2 2 1 ANTH domain I_LWEQ PF01608.12 KFM10686.1 - 3.2e-26 92.0 1.6 3.2e-26 92.0 1.1 5.4 3 1 3 6 6 6 1 I/LWEQ domain ENTH PF01417.15 KFM10686.1 - 4.5e-07 29.7 0.0 1.7e-06 27.9 0.0 2.0 1 0 0 1 1 1 1 ENTH domain Laminin_II PF06009.7 KFM10686.1 - 0.049 13.3 0.3 0.049 13.3 0.2 4.9 2 1 1 4 4 4 0 Laminin Domain II DUF3584 PF12128.3 KFM10686.1 - 2.8 5.1 60.6 0.095 10.0 35.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Mod_r PF07200.8 KFM10687.1 - 7e-41 139.6 7.8 9.7e-41 139.1 5.4 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Surf_Ag_VNR PF07244.10 KFM10687.1 - 0.024 15.0 0.2 0.052 13.9 0.1 1.6 1 0 0 1 1 1 0 Surface antigen variable number repeat Muted PF14942.1 KFM10687.1 - 0.11 12.3 2.0 0.36 10.7 0.0 2.1 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein zf-C4H2 PF10146.4 KFM10687.1 - 5.2 7.0 16.0 1.7 8.6 5.3 2.7 1 1 0 2 2 2 0 Zinc finger-containing protein ABC_membrane PF00664.18 KFM10688.1 - 5.4e-54 183.4 17.5 1.1e-53 182.5 12.2 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KFM10688.1 - 1.1e-34 119.6 0.1 2.6e-34 118.4 0.0 1.7 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 KFM10688.1 - 1.2e-10 40.9 1.0 8.8e-08 31.6 0.7 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KFM10688.1 - 2.3e-05 24.4 0.2 5e-05 23.3 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 KFM10688.1 - 4.5e-05 22.6 0.0 0.00011 21.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC_membrane_3 PF13748.1 KFM10688.1 - 0.00015 20.8 4.6 0.00035 19.6 3.2 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 KFM10688.1 - 0.00019 21.5 0.0 0.35 10.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KFM10688.1 - 0.00065 19.1 0.0 0.0015 17.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KFM10688.1 - 0.00081 19.5 0.0 0.0031 17.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain DUF4191 PF13829.1 KFM10688.1 - 0.019 14.0 0.0 0.065 12.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) SbcCD_C PF13558.1 KFM10688.1 - 0.028 14.3 0.5 0.23 11.3 0.4 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.4 KFM10688.1 - 0.038 12.5 0.0 0.13 10.8 0.0 1.8 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_25 PF13481.1 KFM10688.1 - 0.11 11.9 0.1 0.63 9.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KFM10688.1 - 0.11 12.7 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain zf-H2C2 PF09337.5 KFM10689.1 - 2.8e-05 23.4 0.8 4.7e-05 22.6 0.5 1.3 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger DUF2348 PF09807.4 KFM10689.1 - 0.00036 19.7 0.0 0.00047 19.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2348) rve PF00665.21 KFM10689.1 - 0.0025 17.8 0.0 0.005 16.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Nucleopor_Nup85 PF07575.8 KFM10689.1 - 0.083 11.0 0.1 0.11 10.6 0.0 1.1 1 0 0 1 1 1 0 Nup85 Nucleoporin 2OG-FeII_Oxy PF03171.15 KFM10690.1 - 0.013 15.8 0.0 0.029 14.6 0.0 1.6 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily SR-25 PF10500.4 KFM10691.1 - 3.1e-74 249.2 78.1 2.2e-71 239.8 54.2 2.1 1 1 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF936 PF06075.7 KFM10691.1 - 1.9 7.3 39.3 2 7.2 27.2 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Cast PF10174.4 KFM10692.1 - 0.00063 17.9 29.3 0.00063 17.9 20.3 2.5 2 1 0 2 2 2 1 RIM-binding protein of the cytomatrix active zone Tropomyosin PF00261.15 KFM10692.1 - 0.0073 15.4 28.8 0.42 9.6 2.2 3.1 1 1 1 2 2 2 2 Tropomyosin Tup_N PF08581.5 KFM10692.1 - 0.087 13.0 0.2 0.087 13.0 0.1 4.5 3 1 1 4 4 4 0 Tup N-terminal RPW8 PF05659.6 KFM10692.1 - 0.23 11.0 8.4 0.19 11.2 3.2 2.7 2 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 BLOC1_2 PF10046.4 KFM10692.1 - 0.38 10.9 23.6 3.5 7.8 4.8 3.9 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.7 KFM10692.1 - 1.3 8.8 21.8 0.17 11.6 3.4 3.6 2 1 2 4 4 4 0 Laminin Domain II Reo_sigmaC PF04582.7 KFM10692.1 - 2.3 7.3 15.0 0.51 9.4 2.7 3.0 2 1 1 3 3 3 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 KFM10692.1 - 2.5 7.9 12.1 0.85 9.4 1.2 3.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) RF-1 PF00472.15 KFM10693.1 - 7.6e-25 86.9 4.4 9e-25 86.6 3.1 1.1 1 0 0 1 1 1 1 RF-1 domain DUF620 PF04788.7 KFM10693.1 - 0.089 11.9 0.1 0.1 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF620) Tautomerase PF01361.16 KFM10693.1 - 0.14 11.7 0.3 0.61 9.7 0.1 2.2 2 1 0 2 2 2 0 Tautomerase enzyme CDK2AP PF09806.4 KFM10694.1 - 3.1e-22 79.7 0.1 3.6e-22 79.5 0.0 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein AAA_34 PF13872.1 KFM10695.1 - 5e-137 455.6 0.0 7.2e-137 455.1 0.0 1.2 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Helicase_C_4 PF13871.1 KFM10695.1 - 9e-117 389.4 0.0 1.5e-116 388.6 0.0 1.4 1 0 0 1 1 1 1 Helicase_C-like ResIII PF04851.10 KFM10695.1 - 1.6e-06 28.0 0.5 6.2e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KFM10695.1 - 0.0024 17.6 0.1 0.0077 16.0 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SET PF00856.23 KFM10696.1 - 1.8e-19 70.6 0.2 1.8e-19 70.6 0.1 2.6 2 2 0 2 2 2 1 SET domain RILP PF11461.3 KFM10697.1 - 7.3e-21 74.0 2.5 7.3e-21 74.0 1.7 1.9 2 0 0 2 2 2 1 Rab interacting lysosomal protein Jnk-SapK_ap_N PF09744.4 KFM10697.1 - 0.019 14.9 2.8 0.15 12.0 0.0 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Cep57_CLD_2 PF14197.1 KFM10697.1 - 1.5 8.8 8.3 4.5 7.2 0.6 2.7 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 RRM_1 PF00076.17 KFM10698.1 - 6.3e-18 64.1 0.1 9.7e-18 63.5 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM10698.1 - 1.7e-11 43.9 0.0 2.6e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM10698.1 - 1e-06 28.4 0.0 1.5e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RILP PF11461.3 KFM10699.1 - 2.6e-24 85.1 3.4 2.6e-24 85.1 2.4 2.7 3 0 0 3 3 3 1 Rab interacting lysosomal protein Jnk-SapK_ap_N PF09744.4 KFM10699.1 - 3.5e-15 56.3 7.5 3.5e-15 56.3 5.2 3.4 2 1 1 4 4 4 1 JNK_SAPK-associated protein-1 YflT PF11181.3 KFM10699.1 - 0.013 15.6 5.1 0.016 15.3 2.2 2.2 2 0 0 2 2 2 0 Heat induced stress protein YflT UBA_e1_C PF09358.5 KFM10699.1 - 0.33 11.1 0.1 0.33 11.1 0.1 2.6 2 2 0 2 2 2 0 Ubiquitin-activating enzyme e1 C-terminal domain TK PF00265.13 KFM10699.1 - 0.38 10.3 2.0 0.57 9.7 0.8 1.7 1 1 1 2 2 2 0 Thymidine kinase DUF4407 PF14362.1 KFM10699.1 - 2.4 7.0 16.5 4.1 6.2 0.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) AATF-Che1 PF13339.1 KFM10699.1 - 9.1 6.4 19.7 4.8 7.3 1.6 3.5 1 1 2 3 3 3 0 Apoptosis antagonizing transcription factor IncA PF04156.9 KFM10699.1 - 9.5 5.7 34.0 9.1 5.8 7.9 2.2 1 1 1 2 2 2 0 IncA protein EMP24_GP25L PF01105.19 KFM10700.1 - 5.1e-39 133.8 0.1 5.6e-39 133.7 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DEAD PF00270.24 KFM10701.1 - 5.8e-38 130.0 0.0 5.8e-38 130.0 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KFM10701.1 - 5.2e-21 73.9 0.3 1.2e-20 72.7 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KFM10701.1 - 3.4e-20 71.6 0.1 2.7e-19 68.7 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4137 PF13593.1 KFM10701.1 - 0.013 14.6 0.0 0.019 14.0 0.0 1.1 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) AAA_22 PF13401.1 KFM10701.1 - 0.1 12.7 0.2 0.34 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain SHOCT PF09851.4 KFM10701.1 - 0.79 9.2 8.6 0.046 13.1 0.7 2.9 3 0 0 3 3 3 0 Short C-terminal domain IF-2B PF01008.12 KFM10702.1 - 6.2e-74 248.4 0.0 7.8e-74 248.1 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Tfb4 PF03850.9 KFM10703.1 - 6.4e-98 327.4 0.2 7.6e-98 327.1 0.1 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 VWA_2 PF13519.1 KFM10703.1 - 0.026 14.6 0.0 0.035 14.1 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain Baculo_IE-1 PF05290.6 KFM10703.1 - 3 7.5 9.2 0.66 9.6 3.4 2.0 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) DUF1619 PF07773.6 KFM10704.1 - 1.3e-56 192.6 4.2 2.7e-56 191.5 2.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1619) V_ATPase_I PF01496.14 KFM10705.1 - 1e-293 975.9 9.4 1.2e-293 975.7 6.5 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF2205 PF10224.4 KFM10705.1 - 0.017 14.6 0.5 0.037 13.5 0.4 1.5 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) DUF4404 PF14357.1 KFM10705.1 - 3.6 8.0 7.1 2.1 8.8 1.5 2.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4404) CCDC92 PF14916.1 KFM10706.1 - 7.4e-24 83.1 9.5 1.5e-22 78.9 1.7 2.7 1 1 1 2 2 2 2 Coiled-coil domain of unknown function Sigma54_DBD PF04552.8 KFM10706.1 - 0.0056 16.1 2.7 0.011 15.2 1.9 1.4 1 0 0 1 1 1 1 Sigma-54, DNA binding domain Angiomotin_C PF12240.3 KFM10706.1 - 0.0091 15.5 7.0 0.0091 15.5 4.8 2.0 1 1 0 2 2 2 1 Angiomotin C terminal CENP-F_leu_zip PF10473.4 KFM10706.1 - 0.024 14.5 23.5 0.49 10.2 0.6 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rootletin PF15035.1 KFM10706.1 - 0.039 13.9 16.3 0.26 11.2 11.1 2.1 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF4407 PF14362.1 KFM10706.1 - 0.052 12.5 3.9 0.084 11.8 2.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Med30 PF11315.3 KFM10706.1 - 0.068 13.3 7.4 0.028 14.5 3.2 1.7 1 1 1 2 2 2 0 Mediator complex subunit 30 DUF2775 PF10950.3 KFM10706.1 - 0.26 11.5 2.5 7.8 6.7 1.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2775) DUF3584 PF12128.3 KFM10706.1 - 0.32 8.2 13.0 0.42 7.8 9.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) V_ATPase_I PF01496.14 KFM10706.1 - 0.47 8.2 8.8 0.61 7.8 6.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NYD-SP28 PF14772.1 KFM10706.1 - 0.59 10.2 12.0 1.3 9.1 5.0 2.5 2 0 0 2 2 2 0 Sperm tail Atg14 PF10186.4 KFM10706.1 - 0.84 8.5 15.4 2.2 7.1 10.2 1.8 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 KFM10706.1 - 1.1 8.8 22.8 3.3 7.2 0.9 3.0 1 1 0 2 2 2 0 IncA protein APG6 PF04111.7 KFM10706.1 - 1.3 7.9 18.5 2.5 7.0 12.8 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 FlxA PF14282.1 KFM10706.1 - 1.4 8.9 16.5 1.4 8.8 0.8 3.3 1 1 2 3 3 3 0 FlxA-like protein DUF812 PF05667.6 KFM10706.1 - 2.2 6.6 18.9 0.04 12.4 4.9 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF812) HrpB7 PF09486.5 KFM10706.1 - 2.4 8.0 11.3 11 5.9 0.1 3.1 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) bZIP_1 PF00170.16 KFM10706.1 - 2.5 8.1 20.2 1.8 8.6 4.5 3.3 2 1 1 3 3 3 0 bZIP transcription factor Reo_sigmaC PF04582.7 KFM10706.1 - 3.1 6.8 7.4 4.5 6.3 3.6 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF869 PF05911.6 KFM10706.1 - 4.5 5.3 21.2 1.6 6.8 10.4 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) MSG PF02349.10 KFM10706.1 - 7.8 6.5 11.3 19 5.3 7.4 2.0 1 1 1 2 2 2 0 Major surface glycoprotein GAS PF13851.1 KFM10706.1 - 9.5 5.3 22.2 14 4.7 10.3 2.1 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding FAM101 PF15068.1 KFM10707.1 - 1.2e-97 325.3 0.1 1.4e-97 325.1 0.0 1.0 1 0 0 1 1 1 1 FAM101 family CD36 PF01130.16 KFM10708.1 - 3.4e-141 470.7 0.7 3.9e-141 470.5 0.5 1.0 1 0 0 1 1 1 1 CD36 family ubiquitin PF00240.18 KFM10709.1 - 4.9e-36 121.9 0.5 5.6e-36 121.7 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KFM10709.1 - 4.1e-21 74.4 0.4 4.6e-21 74.2 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KFM10709.1 - 3.5e-07 30.3 0.1 1.5e-06 28.3 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KFM10709.1 - 6.4e-05 22.6 0.0 7.2e-05 22.5 0.0 1.0 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 KFM10709.1 - 0.0015 18.3 0.1 0.0033 17.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KFM10709.1 - 0.012 15.8 0.0 0.013 15.6 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain TUG-UBL1 PF11470.3 KFM10709.1 - 0.02 14.8 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 GLUT4 regulating protein TUG DUF2870 PF11069.3 KFM10709.1 - 0.065 13.2 0.0 0.2 11.7 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 KFM10709.1 - 0.17 10.1 0.5 2.3 6.4 0.1 1.9 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain OB_NTP_bind PF07717.11 KFM10710.1 - 1.7e-25 89.0 0.0 4.1e-25 87.8 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KFM10710.1 - 1.1e-17 63.8 0.1 1.1e-17 63.8 0.0 2.8 4 0 0 4 4 3 1 Helicase associated domain (HA2) DEAD PF00270.24 KFM10710.1 - 6.4e-12 45.2 0.2 6.4e-12 45.2 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFM10710.1 - 5.9e-11 42.0 0.0 2e-10 40.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KFM10710.1 - 1.6e-07 31.5 2.4 4.1e-07 30.1 0.0 2.8 4 0 0 4 4 3 1 AAA domain T2SE PF00437.15 KFM10710.1 - 0.0011 17.9 0.0 0.0042 16.0 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein Flavi_DEAD PF07652.9 KFM10710.1 - 0.0022 17.7 1.6 0.033 13.9 0.0 3.1 3 0 0 3 3 3 1 Flavivirus DEAD domain KaiC PF06745.8 KFM10710.1 - 0.0041 16.2 0.1 0.0084 15.2 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_19 PF13245.1 KFM10710.1 - 0.005 16.5 0.0 0.017 14.8 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KFM10710.1 - 0.0064 16.0 0.0 0.017 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 KFM10710.1 - 0.026 13.4 0.0 0.026 13.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.13 KFM10710.1 - 0.028 13.9 0.0 0.062 12.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.1 KFM10710.1 - 0.03 14.6 0.0 0.03 14.6 0.0 3.1 2 1 0 2 2 1 0 AAA domain ABC_tran PF00005.22 KFM10710.1 - 0.16 12.2 4.5 0.46 10.7 0.1 2.8 2 1 0 2 2 2 0 ABC transporter ResIII PF04851.10 KFM10710.1 - 0.2 11.4 0.0 0.2 11.4 0.0 3.7 3 2 1 4 4 3 0 Type III restriction enzyme, res subunit AAA_14 PF13173.1 KFM10710.1 - 0.22 11.4 1.9 0.5 10.2 0.1 2.4 2 1 0 2 2 2 0 AAA domain BRI3BP PF14965.1 KFM10711.1 - 3.2e-72 241.5 1.0 3.6e-72 241.4 0.7 1.0 1 0 0 1 1 1 1 Negative regulator of p53/TP53 Myosin_head PF00063.16 KFM10712.1 - 1.8e-270 898.8 1.4 1.8e-270 898.8 1.0 2.6 3 0 0 3 3 1 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 KFM10712.1 - 6.5e-111 371.5 135.9 3e-106 356.1 47.3 3.2 2 1 1 3 3 3 3 Myosin tail Myosin_N PF02736.14 KFM10712.1 - 2.6e-14 52.5 1.3 7.1e-14 51.1 0.9 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Reo_sigmaC PF04582.7 KFM10712.1 - 5.1e-06 25.8 36.9 0.03 13.4 3.5 4.8 1 1 4 5 5 5 5 Reovirus sigma C capsid protein Filament PF00038.16 KFM10712.1 - 9.4e-05 22.0 109.7 0.0076 15.7 34.2 5.0 1 1 3 4 4 4 2 Intermediate filament protein DUF869 PF05911.6 KFM10712.1 - 0.0017 16.7 7.2 0.0017 16.7 5.0 4.3 1 1 3 4 4 4 2 Plant protein of unknown function (DUF869) IQ PF00612.22 KFM10712.1 - 0.013 15.0 1.2 0.037 13.6 0.2 2.3 2 0 0 2 2 2 0 IQ calmodulin-binding motif AAA_22 PF13401.1 KFM10712.1 - 0.061 13.4 3.2 0.14 12.2 0.0 3.3 2 1 0 2 2 2 0 AAA domain GAS PF13851.1 KFM10712.1 - 0.069 12.3 119.5 0.53 9.4 17.7 5.9 1 1 4 5 5 5 0 Growth-arrest specific micro-tubule binding AAA_16 PF13191.1 KFM10712.1 - 0.13 12.2 0.0 0.13 12.2 0.0 4.2 2 1 0 3 3 1 0 AAA ATPase domain AAA_27 PF13514.1 KFM10712.1 - 0.61 7.7 98.3 0.88 7.1 68.1 1.1 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 KFM10712.1 - 0.69 9.4 128.1 0.056 13.0 12.4 6.4 1 1 6 7 7 7 0 IncA protein Myosin_tail_1 PF01576.14 KFM10714.1 - 3.5e-82 276.5 46.8 3.9e-82 276.3 32.4 1.0 1 0 0 1 1 1 1 Myosin tail Tropomyosin PF00261.15 KFM10714.1 - 0.00021 20.4 42.5 0.035 13.1 8.5 3.0 1 1 2 3 3 3 2 Tropomyosin Lipoprotein_7 PF01540.11 KFM10714.1 - 0.0056 15.7 18.4 0.008 15.2 12.4 1.5 1 1 0 1 1 1 1 Adhesin lipoprotein Bacillus_HBL PF05791.6 KFM10714.1 - 0.012 14.9 22.9 0.019 14.3 4.2 3.0 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Laminin_I PF06008.9 KFM10714.1 - 0.083 12.1 29.7 0.12 11.6 12.7 2.3 1 1 1 2 2 2 0 Laminin Domain I Reo_sigmaC PF04582.7 KFM10714.1 - 0.13 11.4 4.2 1.3 8.1 0.7 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein HMGL-like PF00682.14 KFM10714.1 - 0.14 11.7 3.7 0.18 11.4 0.7 2.2 1 1 1 2 2 2 0 HMGL-like Tropomyosin_1 PF12718.2 KFM10714.1 - 0.21 11.4 43.3 1.7 8.4 17.6 2.7 1 1 1 2 2 2 0 Tropomyosin like NikR_C PF08753.6 KFM10714.1 - 0.35 10.7 2.8 3.3 7.6 0.7 3.0 2 1 0 2 2 2 0 NikR C terminal nickel binding domain Fib_alpha PF08702.5 KFM10714.1 - 0.87 9.7 26.0 0.13 12.3 8.2 2.9 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family IncA PF04156.9 KFM10714.1 - 1.8 8.1 39.7 0.58 9.7 11.1 3.0 1 1 2 3 3 3 0 IncA protein Laminin_II PF06009.7 KFM10714.1 - 2 8.1 23.8 1 9.1 3.5 3.2 1 1 3 4 4 4 0 Laminin Domain II PspA_IM30 PF04012.7 KFM10714.1 - 2.6 7.3 40.2 2.5 7.4 15.4 3.1 1 1 1 2 2 2 0 PspA/IM30 family HrpF PF06266.7 KFM10714.1 - 2.9 8.0 8.0 2.3 8.4 0.2 3.1 2 1 2 4 4 4 0 HrpF protein DUF1664 PF07889.7 KFM10714.1 - 5.5 6.8 26.6 0.76 9.5 5.0 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) FliJ PF02050.11 KFM10714.1 - 5.7 7.0 35.2 5 7.2 6.4 3.0 1 1 1 2 2 2 0 Flagellar FliJ protein NPV_P10 PF05531.7 KFM10714.1 - 6.1 7.1 13.3 11 6.3 0.9 3.9 1 1 4 5 5 5 0 Nucleopolyhedrovirus P10 protein FUSC PF04632.7 KFM10714.1 - 7.4 4.8 9.4 4.1 5.7 4.5 1.6 1 1 1 2 2 2 0 Fusaric acid resistance protein family APG6 PF04111.7 KFM10714.1 - 7.7 5.4 38.0 3.3 6.6 13.3 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 AAA_13 PF13166.1 KFM10714.1 - 8.2 4.7 29.8 18 3.6 20.6 1.5 1 1 0 1 1 1 0 AAA domain TraN PF06986.6 KFM10716.1 - 0.076 12.3 0.3 0.082 12.2 0.2 1.0 1 0 0 1 1 1 0 Type-1V conjugative transfer system mating pair stabilisation Myosin_tail_1 PF01576.14 KFM10718.1 - 6.6e-133 444.3 82.4 7.5e-133 444.1 57.1 1.0 1 0 0 1 1 1 1 Myosin tail Tropomyosin PF00261.15 KFM10718.1 - 0.036 13.1 78.7 0.021 13.8 4.5 4.9 1 1 3 4 4 4 0 Tropomyosin Reo_sigmaC PF04582.7 KFM10718.1 - 0.82 8.7 15.1 0.62 9.1 0.5 2.8 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Laminin_I PF06008.9 KFM10718.1 - 2.4 7.3 58.4 0.42 9.8 11.0 3.7 1 1 2 3 3 3 0 Laminin Domain I MtrB PF05440.7 KFM10718.1 - 3.3 7.8 5.3 5.2 7.1 0.1 3.7 1 1 1 4 4 4 0 Tetrahydromethanopterin S-methyltransferase subunit B PspA_IM30 PF04012.7 KFM10718.1 - 4.4 6.5 73.9 0.015 14.6 23.3 4.9 1 1 2 3 3 3 0 PspA/IM30 family WEMBL PF05701.6 KFM10718.1 - 4.8 5.5 74.0 0.2 10.0 34.8 2.2 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Filament PF00038.16 KFM10718.1 - 6.3 6.1 67.4 0.91 8.9 33.5 3.3 1 1 2 3 3 3 0 Intermediate filament protein FCH PF00611.18 KFM10720.1 - 7.2e-22 77.3 5.2 7.2e-22 77.3 3.6 2.5 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain WW PF00397.21 KFM10720.1 - 1.8e-11 43.6 3.3 3.9e-11 42.5 2.3 1.6 1 0 0 1 1 1 1 WW domain DUF1664 PF07889.7 KFM10720.1 - 0.0039 16.9 4.6 0.0039 16.9 3.2 2.2 1 1 2 3 3 3 1 Protein of unknown function (DUF1664) Lectin_N PF03954.9 KFM10720.1 - 0.059 12.7 1.5 0.12 11.8 1.0 1.6 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain Atg14 PF10186.4 KFM10720.1 - 0.16 10.9 19.4 0.17 10.7 9.1 2.6 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2229 PF09989.4 KFM10720.1 - 2.9 7.2 8.1 0.57 9.6 2.6 1.9 1 1 1 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) TPR_MLP1_2 PF07926.7 KFM10720.1 - 7 6.4 26.3 0.66 9.7 1.8 3.1 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein 7tm_2 PF00002.19 KFM10721.1 - 2.4e-79 265.8 17.6 2.9e-79 265.5 12.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 KFM10721.1 - 1.1e-14 54.1 3.8 2.7e-14 52.8 2.6 1.7 1 0 0 1 1 1 1 Hormone receptor domain SUR7 PF06687.7 KFM10721.1 - 0.002 17.7 0.3 0.002 17.7 0.2 1.6 2 0 0 2 2 2 1 SUR7/PalI family GSG-1 PF07803.6 KFM10722.1 - 2.3e-42 143.3 0.4 4e-42 142.5 0.2 1.4 1 0 0 1 1 1 1 GSG1-like protein Claudin_2 PF13903.1 KFM10722.1 - 4e-11 42.8 6.0 6.5e-11 42.2 4.1 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 KFM10722.1 - 1.7e-08 34.2 8.3 3.3e-08 33.3 5.7 1.7 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family L_HGMIC_fpl PF10242.4 KFM10722.1 - 0.0055 16.7 6.8 0.017 15.1 4.7 1.8 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein CD20 PF04103.10 KFM10722.1 - 0.4 10.6 9.3 3.9 7.4 3.6 3.1 3 1 0 3 3 3 0 CD20-like family adh_short PF00106.20 KFM10723.1 - 1.5e-23 83.5 0.0 2e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFM10723.1 - 2.6e-06 27.2 0.0 3.9e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFM10723.1 - 1.5e-05 24.8 0.0 2.2e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KFM10723.1 - 0.0017 17.5 0.0 0.0039 16.3 0.0 1.5 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) PepSY_TM_1 PF13172.1 KFM10723.1 - 1.3 8.8 3.6 2.8 7.7 2.5 1.6 1 0 0 1 1 1 0 PepSY-associated TM helix Tim17 PF02466.14 KFM10725.1 - 2.5e-18 66.3 0.3 3.5e-18 65.8 0.2 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family zf-H2C2_2 PF13465.1 KFM10726.1 - 1e-37 126.5 94.2 1.3e-08 34.6 0.0 13.4 13 0 0 13 13 13 9 Zinc-finger double domain zf-C2H2 PF00096.21 KFM10726.1 - 2.5e-34 115.5 111.7 9.1e-05 22.5 0.9 12.4 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM10726.1 - 9.2e-31 103.9 98.9 0.0014 18.8 0.2 12.3 12 0 0 12 12 12 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM10726.1 - 6.2e-12 45.3 79.7 0.006 16.6 1.7 11.9 11 1 1 12 12 12 8 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFM10726.1 - 2.3e-07 30.4 79.1 0.026 14.4 2.8 11.8 12 0 0 12 12 12 6 C2H2-type zinc finger BolA PF01722.13 KFM10726.1 - 3e-05 23.9 13.6 0.0015 18.4 0.1 4.3 4 2 1 5 5 5 2 BolA-like protein zf-met PF12874.2 KFM10726.1 - 3.9e-05 23.7 75.7 0.84 9.9 2.8 11.6 12 0 0 12 12 12 7 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KFM10726.1 - 0.00028 20.9 65.2 0.19 11.8 0.6 8.5 2 2 5 8 8 8 5 C2H2 type zinc-finger (2 copies) GAGA PF09237.6 KFM10726.1 - 0.0012 18.3 10.3 1.3 8.7 0.5 4.0 3 0 0 3 3 3 3 GAGA factor RRN7 PF11781.3 KFM10726.1 - 0.59 9.6 6.0 43 3.7 0.0 4.6 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-FPG_IleRS PF06827.9 KFM10726.1 - 0.96 9.1 11.5 0.35 10.5 0.8 4.4 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS Snf7 PF03357.16 KFM10727.1 - 3.1e-46 156.8 8.5 3.4e-46 156.7 5.9 1.0 1 0 0 1 1 1 1 Snf7 SYF2 PF08231.7 KFM10727.1 - 0.035 14.2 1.0 0.054 13.6 0.7 1.2 1 0 0 1 1 1 0 SYF2 splicing factor AAA_27 PF13514.1 KFM10727.1 - 0.047 11.3 5.6 0.053 11.2 3.9 1.0 1 0 0 1 1 1 0 AAA domain Enkurin PF13864.1 KFM10727.1 - 0.39 10.9 7.1 0.56 10.4 0.1 2.6 1 1 0 2 2 2 0 Calmodulin-binding CHASE3 PF05227.8 KFM10727.1 - 0.66 9.6 5.5 0.78 9.4 0.1 2.6 1 1 2 3 3 3 0 CHASE3 domain Cwf_Cwc_15 PF04889.7 KFM10727.1 - 1.4 8.5 5.5 1.7 8.3 3.8 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Tropomodulin PF03250.9 KFM10727.1 - 3.7 7.0 9.7 0.26 10.7 1.4 2.4 1 1 2 3 3 3 0 Tropomodulin GreA_GreB_N PF03449.10 KFM10727.1 - 8.6 6.4 8.3 12 6.0 0.2 3.0 2 1 0 3 3 3 0 Transcription elongation factor, N-terminal Perilipin PF03036.11 KFM10728.1 - 2.3e-47 161.6 1.8 2.5e-47 161.5 1.3 1.0 1 0 0 1 1 1 1 Perilipin family RRM_1 PF00076.17 KFM10729.1 - 2.1e-12 46.4 0.0 3.6e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM10729.1 - 4.7e-08 32.7 0.0 9.5e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM10729.1 - 6.9e-08 32.3 0.0 1.1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF4611 PF15387.1 KFM10729.1 - 0.0036 17.4 2.7 0.0062 16.6 1.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) BUD22 PF09073.5 KFM10729.1 - 0.014 14.4 2.2 0.02 13.9 1.5 1.1 1 0 0 1 1 1 0 BUD22 RP-C_C PF11800.3 KFM10729.1 - 0.085 12.5 2.5 0.12 12.0 1.7 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region eIF-5_eIF-2B PF01873.12 KFM10730.1 - 2.7e-50 169.1 1.2 4.6e-50 168.4 0.8 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Cupin_8 PF13621.1 KFM10730.1 - 2 7.8 6.3 1.5 8.2 3.2 1.6 2 0 0 2 2 2 0 Cupin-like domain Cytochrom_c3_2 PF14537.1 KFM10730.1 - 9 6.7 8.3 0.28 11.5 0.7 2.2 2 1 0 2 2 2 0 Cytochrome c3 Agouti PF05039.7 KFM10731.1 - 1.7e-18 66.7 13.5 1.8e-18 66.6 9.0 1.3 1 1 0 1 1 1 1 Agouti protein AdoHcyase PF05221.12 KFM10732.1 - 1.4e-143 476.7 0.1 1.7e-143 476.4 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 KFM10732.1 - 2.3e-87 290.9 3.1 3.6e-87 290.2 2.2 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 KFM10732.1 - 1.2e-09 37.5 0.1 2.2e-09 36.7 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 KFM10732.1 - 5.6e-06 25.8 0.2 9.5e-06 25.0 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 KFM10732.1 - 0.00063 19.7 0.1 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.13 KFM10732.1 - 0.0024 17.5 1.1 0.0099 15.5 0.8 2.2 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 KFM10732.1 - 0.0081 15.2 0.9 0.04 12.9 0.6 2.1 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Oxidored_nitro PF00148.14 KFM10732.1 - 0.013 14.1 0.1 1.6 7.2 0.0 2.3 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase ELFV_dehydrog PF00208.16 KFM10732.1 - 0.015 14.8 0.3 0.027 14.0 0.1 1.6 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Shikimate_DH PF01488.15 KFM10732.1 - 0.018 15.1 0.2 0.036 14.1 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF4448 PF14610.1 KFM10732.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) NAD_binding_7 PF13241.1 KFM10732.1 - 0.13 12.5 0.2 0.3 11.3 0.2 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding HECT PF00632.20 KFM10733.1 - 9.3e-96 320.6 0.2 1.3e-95 320.2 0.1 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 KFM10733.1 - 1.2e-43 146.5 20.5 7e-13 48.1 0.6 4.6 4 0 0 4 4 4 4 WW domain C2 PF00168.25 KFM10733.1 - 2e-12 46.7 0.4 5.2e-12 45.4 0.3 1.8 1 0 0 1 1 1 1 C2 domain DUF605 PF04652.11 KFM10733.1 - 0.33 10.3 8.1 0.47 9.8 5.6 1.2 1 0 0 1 1 1 0 Vta1 like Robl_LC7 PF03259.12 KFM10734.1 - 9e-27 92.4 0.0 9.8e-27 92.3 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain Atg8 PF02991.11 KFM10735.1 - 2.4e-45 152.7 0.4 2.7e-45 152.5 0.3 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 KFM10735.1 - 2.1e-06 27.8 0.0 2.5e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Telomere_Sde2 PF13019.1 KFM10735.1 - 0.076 12.6 0.0 0.087 12.5 0.0 1.1 1 0 0 1 1 1 0 Telomere stability and silencing DUF1669 PF07894.7 KFM10736.1 - 3.4e-98 328.3 0.1 6.2e-98 327.5 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1669) PLDc_2 PF13091.1 KFM10736.1 - 0.0097 15.6 0.0 0.019 14.6 0.0 1.5 1 1 0 1 1 1 1 PLD-like domain Ubiq_cyt_C_chap PF03981.7 KFM10737.1 - 3.7e-42 143.5 0.1 5e-42 143.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Chlorophyllase PF07224.6 KFM10737.1 - 0.079 11.7 0.4 0.12 11.1 0.3 1.2 1 0 0 1 1 1 0 Chlorophyllase TGF_beta PF00019.15 KFM10738.1 - 4.6e-38 129.7 0.6 8.8e-38 128.8 0.4 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.13 KFM10738.1 - 1.3e-19 70.4 0.1 2.1e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 TGF-beta propeptide Arrestin_N PF00339.24 KFM10739.1 - 2e-32 112.0 0.0 2.4e-31 108.5 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KFM10739.1 - 5.2e-27 94.5 0.0 2.4e-21 76.2 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Vps26 PF03643.10 KFM10739.1 - 0.0011 17.8 0.0 0.0014 17.5 0.0 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 LDB19 PF13002.2 KFM10739.1 - 0.052 13.0 0.0 0.13 11.7 0.0 1.5 2 0 0 2 2 2 0 Arrestin_N terminal like DUF4601 PF15373.1 KFM10740.1 - 4.2e-69 233.5 13.2 5.1e-69 233.2 9.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4601) STOP PF05217.7 KFM10740.1 - 0.011 15.5 1.3 0.011 15.5 0.9 3.2 1 1 1 3 3 3 0 STOP protein PEX11 PF05648.9 KFM10741.1 - 3.2e-43 147.5 0.0 3.5e-43 147.4 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF330 PF03886.8 KFM10741.1 - 0.018 14.4 0.2 0.027 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF330) PsbJ PF01788.12 KFM10741.1 - 0.038 13.5 1.5 0.1 12.1 1.0 1.6 1 0 0 1 1 1 0 PsbJ HIG_1_N PF04588.8 KFM10741.1 - 0.072 12.8 0.1 0.22 11.2 0.0 1.8 1 0 0 1 1 1 0 Hypoxia induced protein conserved region Kelch_1 PF01344.20 KFM10742.1 - 8.3e-47 156.5 0.2 2.7e-11 42.8 0.0 6.1 5 1 1 6 6 6 5 Kelch motif BACK PF07707.10 KFM10742.1 - 1.5e-29 101.8 1.5 2.4e-29 101.2 0.6 1.7 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.26 KFM10742.1 - 2e-26 92.1 0.2 3.6e-26 91.3 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.1 KFM10742.1 - 3.4e-26 90.2 4.4 9.1e-08 31.9 0.3 6.2 1 1 5 6 6 6 4 Kelch motif Kelch_3 PF13415.1 KFM10742.1 - 7.3e-22 76.9 0.1 4.8e-07 29.7 0.0 6.2 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_4 PF13418.1 KFM10742.1 - 1.4e-18 66.3 2.2 2.5e-06 27.1 0.0 5.6 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.10 KFM10742.1 - 9.1e-17 60.0 8.5 7.2e-05 22.4 0.2 5.4 4 1 0 4 4 4 3 Kelch motif Kelch_5 PF13854.1 KFM10742.1 - 2.6e-15 55.9 1.9 7.2e-07 29.0 0.0 6.2 6 0 0 6 6 6 3 Kelch motif DUF3342 PF11822.3 KFM10742.1 - 0.0019 17.3 0.1 0.0029 16.7 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) HTH_12 PF08461.5 KFM10742.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain PQQ_3 PF13570.1 KFM10742.1 - 2.1 8.7 4.9 2.7 8.3 0.0 3.3 4 1 0 4 4 4 0 PQQ-like domain RhoGEF PF00621.15 KFM10743.1 - 1.5e-36 125.9 3.8 1.5e-36 125.9 2.6 2.4 2 1 0 2 2 2 1 RhoGEF domain PH PF00169.24 KFM10743.1 - 1.6e-07 31.4 0.1 6.4e-07 29.5 0.0 2.1 2 0 0 2 2 2 1 PH domain Pkinase_Tyr PF07714.12 KFM10744.1 - 7.6e-98 326.7 0.0 1.8e-97 325.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Recep_L_domain PF01030.19 KFM10744.1 - 1.1e-58 196.0 2.3 5.7e-29 100.3 0.1 2.5 2 0 0 2 2 2 2 Receptor L domain Pkinase PF00069.20 KFM10744.1 - 6.2e-42 143.5 0.0 1.2e-41 142.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Furin-like PF00757.15 KFM10744.1 - 3.9e-37 127.1 43.9 1.1e-36 125.7 30.4 1.8 1 0 0 1 1 1 1 Furin-like cysteine rich region fn3 PF00041.16 KFM10744.1 - 3.1e-21 75.2 1.5 1.1e-07 31.8 0.0 5.1 4 1 0 4 4 4 4 Fibronectin type III domain Kinase-like PF14531.1 KFM10744.1 - 0.00011 21.3 0.0 0.00017 20.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like B2 PF11473.3 KFM10744.1 - 0.075 12.6 0.0 0.31 10.6 0.0 2.1 2 0 0 2 2 2 0 RNA binding protein B2 Toxin_29 PF08116.6 KFM10744.1 - 3.6 7.4 17.1 0.097 12.4 6.8 2.3 2 0 0 2 2 2 0 PhTx neurotoxin family Myosin_head PF00063.16 KFM10745.1 - 5.6e-212 705.5 3.5 5.6e-212 705.5 2.4 2.6 2 1 0 2 2 2 1 Myosin head (motor domain) RhoGAP PF00620.22 KFM10745.1 - 1.3e-47 161.1 0.2 5.1e-47 159.2 0.1 2.1 1 0 0 1 1 1 1 RhoGAP domain RA PF00788.18 KFM10745.1 - 3.3e-14 53.1 4.1 3.5e-14 53.0 0.0 3.3 3 0 0 3 3 3 1 Ras association (RalGDS/AF-6) domain IQ PF00612.22 KFM10745.1 - 1.6e-09 36.5 32.6 0.0007 19.0 0.8 5.3 5 0 0 5 5 5 4 IQ calmodulin-binding motif C1_1 PF00130.17 KFM10745.1 - 0.00041 20.0 17.5 0.0008 19.0 12.1 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) AAA_22 PF13401.1 KFM10745.1 - 0.0036 17.4 0.2 0.28 11.3 0.1 3.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KFM10745.1 - 0.21 11.3 0.1 0.5 10.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain DUF3053 PF11254.3 KFM10746.1 - 0.0062 15.8 0.2 0.0062 15.8 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3053) Baculo_PEP_C PF04513.7 KFM10746.1 - 0.2 11.4 0.9 0.41 10.4 0.2 1.7 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus WHIM3 PF15614.1 KFM10746.1 - 0.3 10.9 1.6 0.71 9.7 1.1 1.7 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 3 FliT PF05400.8 KFM10746.1 - 2.4 8.6 8.9 0.52 10.7 0.5 2.4 2 0 0 2 2 2 0 Flagellar protein FliT A2M_comp PF07678.9 KFM10747.1 - 1.4e-80 270.1 1.0 2.1e-80 269.5 0.7 1.3 1 0 0 1 1 1 1 A-macroglobulin complement component A2M_N_2 PF07703.9 KFM10747.1 - 3.3e-34 117.5 1.8 2.2e-31 108.4 0.0 3.6 3 0 0 3 3 3 1 Alpha-2-macroglobulin family N-terminal region A2M PF00207.17 KFM10747.1 - 6.6e-29 99.3 0.1 6.6e-29 99.3 0.1 3.8 5 0 0 5 5 5 1 Alpha-2-macroglobulin family A2M_recep PF07677.9 KFM10747.1 - 2.9e-28 97.8 0.0 8.4e-28 96.3 0.0 1.9 1 0 0 1 1 1 1 A-macroglobulin receptor Methyltransf_FA PF12248.3 KFM10747.1 - 5e-27 93.8 0.1 1.6e-26 92.3 0.0 1.9 1 0 0 1 1 1 1 Farnesoic acid 0-methyl transferase Thiol-ester_cl PF10569.4 KFM10747.1 - 5.3e-17 60.7 0.1 1.3e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 Alpha-macro-globulin thiol-ester bond-forming region A2M_N PF01835.14 KFM10747.1 - 1.2e-16 60.7 0.0 4.9e-16 58.7 0.0 2.2 1 0 0 1 1 1 1 MG2 domain Prenyltrans_2 PF13249.1 KFM10747.1 - 6.1e-09 36.2 1.8 0.0021 18.4 0.0 3.2 1 1 1 3 3 3 3 Prenyltransferase-like Kazal_2 PF07648.10 KFM10747.1 - 7.3e-08 32.2 2.7 2.1e-07 30.7 1.9 1.8 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Prenyltrans_1 PF13243.1 KFM10747.1 - 0.0012 18.8 0.1 0.016 15.1 0.0 2.5 2 0 0 2 2 2 1 Prenyltransferase-like Rib PF08428.5 KFM10747.1 - 0.0014 18.3 0.3 0.0094 15.6 0.0 2.4 2 0 0 2 2 2 1 Rib/alpha-like repeat Kazal_1 PF00050.16 KFM10747.1 - 0.0016 18.4 10.3 0.0018 18.2 6.0 2.0 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain 7tm_1 PF00001.16 KFM10748.1 - 6.4e-48 163.1 22.2 1e-47 162.4 15.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 KFM10748.1 - 0.00014 21.1 13.0 0.00019 20.6 9.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.4 KFM10748.1 - 0.032 13.3 14.5 0.016 14.3 2.5 2.6 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw PAH PF02671.16 KFM10749.1 - 1.1e-45 153.0 9.5 7.9e-19 67.0 0.2 4.0 4 0 0 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 KFM10749.1 - 1.5e-42 143.3 0.5 1.5e-42 143.3 0.3 2.2 2 0 0 2 2 2 1 Sin3 family co-repressor IL3 PF02059.10 KFM10749.1 - 0.081 12.9 1.5 0.85 9.6 0.0 3.1 3 0 0 3 3 3 0 Interleukin-3 TRIC PF05197.8 KFM10750.1 - 5.2e-91 303.4 6.4 6.5e-91 303.1 4.4 1.1 1 0 0 1 1 1 1 TRIC channel DUF788 PF05620.6 KFM10750.1 - 5.7 6.7 7.4 0.69 9.7 0.4 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF788) DUF2505 PF10698.4 KFM10751.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2505) TPT PF03151.11 KFM10752.1 - 1e-36 125.8 12.5 1e-36 125.8 8.7 2.0 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 KFM10752.1 - 1.8e-09 37.6 16.5 1.9e-05 24.6 5.6 2.3 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 KFM10752.1 - 7.2e-05 22.9 11.6 0.0026 17.9 0.3 2.4 2 0 0 2 2 2 2 Multidrug resistance efflux transporter UAA PF08449.6 KFM10752.1 - 0.00032 19.7 18.7 0.00078 18.4 13.0 1.6 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 KFM10752.1 - 0.014 14.5 10.2 0.19 10.8 1.6 2.7 1 1 1 2 2 2 0 Nucleotide-sugar transporter DUF4131 PF13567.1 KFM10752.1 - 0.03 13.7 5.3 0.4 10.0 3.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) YwiC PF14256.1 KFM10752.1 - 0.56 10.2 6.6 0.092 12.8 0.3 2.2 1 1 1 2 2 2 0 YwiC-like protein G-patch PF01585.18 KFM10753.1 - 2.4e-11 43.2 5.1 5.3e-11 42.1 3.6 1.6 1 0 0 1 1 1 1 G-patch domain CTD_bind PF04818.8 KFM10753.1 - 2.3e-10 40.5 0.2 2.3e-10 40.5 0.2 2.6 2 0 0 2 2 2 1 RNA polymerase II-binding domain. DUF4614 PF15391.1 KFM10754.1 - 2.3e-22 79.6 0.7 2.6e-22 79.4 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4614) Calreticulin PF00262.13 KFM10755.1 - 4.1e-109 364.5 9.1 7.6e-109 363.7 6.3 1.4 1 0 0 1 1 1 1 Calreticulin family EF-hand_4 PF12763.2 KFM10756.1 - 1.5e-42 143.5 0.0 9.9e-23 79.8 0.0 3.6 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 KFM10756.1 - 2.5e-12 45.1 2.3 0.002 17.3 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 KFM10756.1 - 1e-10 41.5 0.4 7.8e-05 22.7 0.1 3.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 KFM10756.1 - 1.9e-08 33.4 0.6 0.12 12.3 0.1 4.5 5 0 0 5 5 4 2 EF-hand domain EF-hand_8 PF13833.1 KFM10756.1 - 0.00014 21.4 2.3 0.046 13.3 0.1 4.0 3 1 1 4 4 4 1 EF-hand domain pair Spc7 PF08317.6 KFM10756.1 - 0.00046 18.9 43.3 0.012 14.2 14.3 2.3 1 1 1 2 2 2 2 Spc7 kinetochore protein BicD PF09730.4 KFM10756.1 - 0.00049 18.6 29.3 0.00075 17.9 20.3 1.2 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D Macoilin PF09726.4 KFM10756.1 - 0.00059 18.2 27.1 0.0011 17.4 18.8 1.3 1 0 0 1 1 1 1 Transmembrane protein EF-hand_9 PF14658.1 KFM10756.1 - 0.00091 19.1 0.7 0.21 11.5 0.0 3.6 4 0 0 4 4 2 1 EF-hand domain EF-hand_5 PF13202.1 KFM10756.1 - 0.0011 18.1 2.4 0.34 10.3 0.1 2.7 2 0 0 2 2 2 2 EF hand Reo_sigmaC PF04582.7 KFM10756.1 - 0.0029 16.8 16.7 0.087 11.9 6.7 2.2 1 1 1 2 2 2 2 Reovirus sigma C capsid protein IncA PF04156.9 KFM10756.1 - 0.0042 16.7 58.2 0.021 14.4 19.5 2.9 2 1 1 3 3 3 2 IncA protein AAA_13 PF13166.1 KFM10756.1 - 0.013 13.9 36.0 0.075 11.4 25.0 1.9 1 1 0 1 1 1 0 AAA domain Prominin PF05478.6 KFM10756.1 - 0.016 12.7 21.8 0.022 12.2 15.1 1.1 1 0 0 1 1 1 0 Prominin EzrA PF06160.7 KFM10756.1 - 0.023 12.8 36.2 0.47 8.5 21.6 2.4 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA DUF4201 PF13870.1 KFM10756.1 - 0.043 13.2 37.8 0.01 15.2 14.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) CALCOCO1 PF07888.6 KFM10756.1 - 0.22 9.7 34.8 0.33 9.1 24.1 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF948 PF06103.6 KFM10756.1 - 0.77 9.6 23.6 0.51 10.2 0.8 3.5 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Atg14 PF10186.4 KFM10756.1 - 0.78 8.6 40.8 1.6 7.5 10.8 2.9 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 KFM10756.1 - 1.1 8.2 50.1 0.22 10.5 9.0 3.0 2 1 1 3 3 3 0 Autophagy protein Apg6 IFT57 PF10498.4 KFM10756.1 - 1.5 7.4 39.5 7 5.2 27.5 1.8 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Filament PF00038.16 KFM10756.1 - 1.6 8.1 42.7 0.82 9.0 8.6 2.5 1 1 1 2 2 2 0 Intermediate filament protein Laminin_II PF06009.7 KFM10756.1 - 4.3 7.0 33.0 1.6 8.4 1.2 3.2 1 1 2 3 3 3 0 Laminin Domain II GAS PF13851.1 KFM10756.1 - 8.3 5.5 45.3 6.5 5.8 12.0 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3584 PF12128.3 KFM10756.1 - 9 3.4 43.0 0.026 11.8 23.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) V_ATPase_I PF01496.14 KFM10756.1 - 9.2 3.9 31.8 7.5 4.2 10.5 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family zf-C2H2 PF00096.21 KFM10757.1 - 2.1e-15 56.0 23.7 2.2e-05 24.5 3.0 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM10757.1 - 9.4e-12 44.4 19.8 0.00099 19.2 1.7 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFM10757.1 - 1.2e-10 41.1 12.7 5.6e-07 29.5 3.1 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFM10757.1 - 0.041 14.0 6.0 3.2 8.0 0.5 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM10757.1 - 0.14 12.3 10.1 1.6 9.0 0.3 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type UPF0172 PF03665.8 KFM10758.1 - 0.0056 16.1 2.2 0.0063 16.0 1.5 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) Wx5_PLAF3D7 PF09688.5 KFM10758.1 - 0.24 11.3 3.8 0.26 11.2 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (Wx5_PLAF3D7) DUF1754 PF08555.5 KFM10758.1 - 0.49 11.0 19.7 0.58 10.7 11.0 2.5 2 1 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) DDE_Tnp_IS240 PF13610.1 KFM10758.1 - 0.68 9.9 4.9 0.78 9.7 3.4 1.1 1 0 0 1 1 1 0 DDE domain Phlebovirus_NSM PF07246.6 KFM10758.1 - 0.71 8.9 7.1 0.77 8.8 4.9 1.0 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M UPF0242 PF06785.6 KFM10758.1 - 1.2 7.7 4.8 1.4 7.5 3.4 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) TRAUB PF08164.7 KFM10758.1 - 3.2 7.9 8.1 1.7 8.7 4.5 1.4 1 1 0 1 1 1 0 Apoptosis-antagonizing transcription factor, C-terminal DUF3395 PF11875.3 KFM10758.1 - 6.5 6.3 11.2 0.77 9.3 2.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3395) EF-hand_7 PF13499.1 KFM10759.1 - 6.6e-15 54.9 5.2 1.8e-12 47.1 0.5 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KFM10759.1 - 4.7e-13 47.4 6.2 1.2e-05 24.2 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 KFM10759.1 - 1e-10 40.5 5.4 0.0045 16.7 0.2 3.8 3 1 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 KFM10759.1 - 4.4e-05 23.0 9.0 0.00096 18.7 0.3 3.2 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 KFM10759.1 - 0.00012 21.2 6.3 0.0011 18.1 0.1 3.5 4 0 0 4 4 4 2 EF hand AF0941-like PF14591.1 KFM10759.1 - 0.005 16.8 0.0 0.019 15.0 0.0 1.9 2 1 0 2 2 2 1 AF0941-like SPARC_Ca_bdg PF10591.4 KFM10759.1 - 0.062 13.3 0.3 0.13 12.3 0.2 1.6 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFM10759.1 - 0.28 10.9 1.9 0.36 10.5 0.1 2.0 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Ras PF00071.17 KFM10760.1 - 5.7e-51 172.1 0.2 6.7e-51 171.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM10760.1 - 3.6e-11 43.6 0.0 6.1e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM10760.1 - 2.6e-10 39.8 0.2 3e-10 39.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFM10760.1 - 0.00058 19.3 0.0 0.00067 19.1 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFM10760.1 - 0.0026 16.9 0.0 0.0034 16.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF3963 PF13124.1 KFM10760.1 - 0.056 13.2 0.4 0.11 12.3 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) Tropomyosin PF00261.15 KFM10761.1 - 1.9e-105 351.1 85.8 2.9e-99 330.9 42.9 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.2 KFM10761.1 - 4.5e-41 140.0 73.7 5.4e-37 126.8 27.9 3.1 2 1 0 2 2 2 2 Tropomyosin like Laminin_II PF06009.7 KFM10761.1 - 9.3e-08 31.9 31.7 0.00023 20.9 4.7 3.3 1 1 2 3 3 3 2 Laminin Domain II MscS_porin PF12795.2 KFM10761.1 - 9.8e-05 21.7 38.6 0.025 13.9 12.3 2.7 1 1 1 2 2 2 2 Mechanosensitive ion channel porin domain Laminin_I PF06008.9 KFM10761.1 - 0.00016 21.0 49.0 0.0009 18.6 8.7 3.1 1 1 2 3 3 3 2 Laminin Domain I TMF_DNA_bd PF12329.3 KFM10761.1 - 0.00057 19.6 14.9 0.00057 19.6 10.3 6.0 1 1 5 6 6 5 3 TATA element modulatory factor 1 DNA binding IncA PF04156.9 KFM10761.1 - 0.0006 19.4 56.8 0.001 18.6 14.9 3.0 1 1 1 2 2 1 1 IncA protein Reo_sigmaC PF04582.7 KFM10761.1 - 0.002 17.3 7.0 0.025 13.7 0.6 2.1 2 0 0 2 2 2 2 Reovirus sigma C capsid protein AAA_13 PF13166.1 KFM10761.1 - 0.0047 15.4 49.6 0.066 11.6 19.9 2.0 1 1 1 2 2 2 2 AAA domain CENP-F_leu_zip PF10473.4 KFM10761.1 - 0.0063 16.3 66.2 0.021 14.6 21.7 2.5 2 1 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.6 KFM10761.1 - 0.013 15.3 52.7 0.014 15.1 7.2 3.7 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) WEMBL PF05701.6 KFM10761.1 - 0.025 13.0 70.3 0.008 14.6 12.7 3.8 1 1 3 4 4 4 0 Weak chloroplast movement under blue light Myosin_tail_1 PF01576.14 KFM10761.1 - 0.026 12.2 67.7 2.4 5.7 46.9 2.5 1 1 0 1 1 1 0 Myosin tail Flagellin_N PF00669.15 KFM10761.1 - 0.074 12.8 13.8 0.58 9.9 2.8 3.6 1 1 1 3 3 3 0 Bacterial flagellin N-terminal helical region DUF869 PF05911.6 KFM10761.1 - 0.099 10.8 52.9 1.5 6.9 19.4 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) RmuC PF02646.11 KFM10761.1 - 0.15 10.9 28.1 0.096 11.5 1.2 3.9 1 1 3 4 4 4 0 RmuC family DUF4200 PF13863.1 KFM10761.1 - 0.29 11.0 67.9 0.51 10.2 18.0 4.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) SlyX PF04102.7 KFM10761.1 - 0.36 11.2 38.1 0.15 12.4 0.6 5.8 2 2 2 5 5 5 0 SlyX NPV_P10 PF05531.7 KFM10761.1 - 0.39 10.9 19.3 2.6 8.3 1.6 4.5 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.5 KFM10761.1 - 0.6 10.2 31.9 0.85 9.7 4.6 3.2 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family EzrA PF06160.7 KFM10761.1 - 0.75 7.8 50.0 5.7 4.9 7.3 3.4 1 1 2 3 3 3 0 Septation ring formation regulator, EzrA ADIP PF11559.3 KFM10761.1 - 0.96 9.3 49.1 1.1 9.1 4.6 4.0 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding FH2 PF02181.18 KFM10761.1 - 1.3 7.7 38.4 0.11 11.3 5.9 3.2 1 1 2 3 3 3 0 Formin Homology 2 Domain APG6 PF04111.7 KFM10761.1 - 1.4 7.9 60.7 3.6 6.5 15.5 3.0 1 1 2 3 3 3 0 Autophagy protein Apg6 DUF3584 PF12128.3 KFM10761.1 - 1.9 5.6 54.1 0.8 6.9 16.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) LOH1CR12 PF10158.4 KFM10761.1 - 2.3 7.9 15.2 0.31 10.8 1.0 3.5 2 2 2 4 4 4 0 Tumour suppressor protein Nup54 PF13874.1 KFM10761.1 - 3.2 7.4 34.4 2.3 7.9 1.0 4.1 1 1 4 5 5 5 0 Nucleoporin complex subunit 54 GAS PF13851.1 KFM10761.1 - 4.5 6.4 61.7 6.1 5.9 11.6 3.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Flagellin_C PF00700.16 KFM10761.1 - 6.4 7.0 14.7 4.5 7.5 0.2 4.4 2 2 2 4 4 4 0 Bacterial flagellin C-terminal helical region Uds1 PF15456.1 KFM10761.1 - 8.1 6.4 49.4 4.6 7.2 4.8 5.4 1 1 4 5 5 5 0 Up-regulated During Septation GTPase_Cys_C PF12631.2 KFM10761.1 - 8.5 6.8 21.4 0.22 11.9 3.2 4.5 1 1 2 3 3 3 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE V_ATPase_I PF01496.14 KFM10761.1 - 8.8 4.0 36.8 34 2.0 25.5 1.9 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Y_phosphatase PF00102.22 KFM10762.1 - 3.4e-173 573.1 0.3 4.5e-88 294.5 0.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.16 KFM10762.1 - 1.7e-112 367.7 23.8 3.4e-17 62.3 0.0 9.5 9 1 0 9 9 9 8 Fibronectin type III domain I-set PF07679.11 KFM10762.1 - 3.9e-41 138.7 0.0 4.6e-16 58.4 0.0 4.6 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM10762.1 - 1e-26 92.8 0.0 7e-08 32.4 0.0 4.1 4 0 0 4 4 4 3 Immunoglobulin domain Ig_3 PF13927.1 KFM10762.1 - 1.1e-19 70.6 7.8 7e-05 23.2 0.0 6.9 8 0 0 8 8 7 3 Immunoglobulin domain Interfer-bind PF09294.5 KFM10762.1 - 2.8e-11 43.3 0.1 0.66 10.0 0.0 6.3 6 0 0 6 6 5 3 Interferon-alpha/beta receptor, fibronectin type III DSPc PF00782.15 KFM10762.1 - 6.1e-09 35.5 0.0 0.0048 16.4 0.0 2.5 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain V-set PF07686.12 KFM10762.1 - 3.7e-08 33.2 0.8 0.12 12.2 0.0 5.5 5 1 0 5 5 5 2 Immunoglobulin V-set domain PTPlike_phytase PF14566.1 KFM10762.1 - 1e-06 28.8 0.1 0.0041 17.1 0.0 3.3 3 0 0 3 3 3 2 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 KFM10762.1 - 1.9e-06 28.2 0.0 0.079 13.2 0.0 2.6 2 0 0 2 2 2 2 Tyrosine phosphatase family C2-set_2 PF08205.7 KFM10762.1 - 4.6e-06 26.4 0.6 0.79 9.6 0.0 4.1 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain DUF2369 PF10179.4 KFM10762.1 - 0.015 14.3 0.1 42 3.1 0.0 4.6 4 1 1 5 5 5 0 Uncharacterised conserved protein (DUF2369) JmjC PF02373.17 KFM10763.1 - 4.6e-44 149.3 0.0 1.3e-43 147.8 0.0 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.1 KFM10763.1 - 1.2e-36 124.9 8.9 1.2e-36 124.9 6.2 2.2 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KFM10763.1 - 2.4e-18 66.0 5.7 2.4e-18 66.0 4.0 3.0 2 0 0 2 2 2 1 PHD-like zinc-binding domain JmjN PF02375.12 KFM10763.1 - 5.2e-14 51.4 0.0 1.3e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 jmjN domain PHD_2 PF13831.1 KFM10763.1 - 2.4e-13 49.1 6.6 2.4e-13 49.1 4.6 2.9 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 KFM10763.1 - 8e-06 25.4 22.4 4.5e-05 23.0 1.8 3.2 3 0 0 3 3 3 2 PHD-finger LBR_tudor PF09465.5 KFM10763.1 - 0.0015 18.0 0.8 0.22 11.1 0.0 2.6 2 0 0 2 2 2 1 Lamin-B receptor of TUDOR domain DUF4537 PF15057.1 KFM10763.1 - 0.03 14.0 0.1 0.37 10.5 0.1 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4537) Rad9_Rad53_bind PF08605.5 KFM10763.1 - 0.037 13.8 0.2 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 Fungal Rad9-like Rad53-binding SAD_SRA PF02182.12 KFM10764.1 - 9.2e-56 187.4 0.1 2e-55 186.3 0.1 1.6 1 0 0 1 1 1 1 SAD/SRA domain DUF3590 PF12148.3 KFM10764.1 - 3.8e-41 138.5 0.5 7.3e-41 137.6 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3590) PHD PF00628.24 KFM10764.1 - 2.1e-12 46.5 7.7 2.1e-12 46.5 5.3 3.6 3 1 0 3 3 3 1 PHD-finger PHD_2 PF13831.1 KFM10764.1 - 0.00062 19.0 0.7 0.00062 19.0 0.5 2.9 4 0 0 4 4 4 1 PHD-finger zf-C3HC4_2 PF13923.1 KFM10764.1 - 0.0008 19.3 12.8 0.0008 19.3 8.9 3.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM10764.1 - 0.00094 18.7 12.3 0.00094 18.7 8.5 3.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM10764.1 - 0.0061 16.3 12.2 0.0061 16.3 8.5 3.0 3 0 0 3 3 3 1 Ring finger domain Tudor-knot PF11717.3 KFM10764.1 - 0.029 14.0 0.0 1.4 8.7 0.0 2.5 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain Perilipin PF03036.11 KFM10765.1 - 5.6e-120 400.7 15.0 6.7e-120 400.4 10.4 1.1 1 0 0 1 1 1 1 Perilipin family PHA_gran_rgn PF09650.5 KFM10765.1 - 0.044 13.8 0.1 0.22 11.6 0.1 2.2 1 0 0 1 1 1 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) Borrelia_REV PF03978.8 KFM10765.1 - 0.13 11.9 4.9 5.4 6.7 0.0 2.9 3 0 0 3 3 3 0 Borrelia burgdorferi REV protein DUF883 PF05957.8 KFM10765.1 - 0.34 11.3 9.0 0.32 11.4 1.9 3.5 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF883) DUF3708 PF12501.3 KFM10765.1 - 1.5 8.6 4.5 10 5.9 0.9 2.4 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter DUF948 PF06103.6 KFM10765.1 - 4.6 7.1 10.3 7.6 6.4 0.0 4.1 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) TIR_2 PF13676.1 KFM10766.1 - 0.0012 18.9 0.0 0.0023 18.0 0.0 1.5 1 0 0 1 1 1 1 TIR domain TIR PF01582.15 KFM10766.1 - 0.032 13.6 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 TIR domain Ank_2 PF12796.2 KFM10767.1 - 7.8e-89 292.1 11.9 1.6e-20 73.2 0.0 5.6 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KFM10767.1 - 1.7e-61 201.0 14.4 4.2e-08 32.5 0.0 8.4 8 0 0 8 8 8 8 Ankyrin repeat Ank_3 PF13606.1 KFM10767.1 - 4.5e-43 140.9 2.6 4.6e-06 26.3 0.0 9.0 8 1 0 8 8 8 8 Ankyrin repeat Ank_5 PF13857.1 KFM10767.1 - 8.6e-43 143.4 11.5 7.6e-10 38.7 0.1 8.0 3 1 5 8 8 8 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFM10767.1 - 1.8e-39 133.3 4.0 1.6e-10 41.1 0.1 6.8 3 2 4 7 7 7 6 Ankyrin repeats (many copies) TPR_12 PF13424.1 KFM10767.1 - 0.0022 17.9 0.1 0.08 12.8 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 KFM10767.1 - 0.029 14.2 0.2 0.55 10.2 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 KFM10767.1 - 0.036 13.9 4.1 0.15 12.0 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DPPIV_N PF00930.16 KFM10768.1 - 2.8e-102 341.9 0.0 3.7e-102 341.5 0.0 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 KFM10768.1 - 1.3e-53 181.3 0.0 2.2e-53 180.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 KFM10768.1 - 6.8e-07 28.9 0.1 1.3e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.2 KFM10768.1 - 2.8e-05 23.8 0.0 7.3e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFM10768.1 - 0.00017 21.5 0.0 0.00042 20.2 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KFM10768.1 - 0.01 15.2 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.11 KFM10768.1 - 0.023 14.1 0.1 7.3 5.9 0.0 2.4 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase DLH PF01738.13 KFM10768.1 - 0.033 13.4 0.0 0.072 12.3 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF4439 PF14530.1 KFM10768.1 - 0.12 12.9 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4439) UPF0556 PF10572.4 KFM10769.1 - 3.9e-66 221.0 0.3 4.3e-66 220.9 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0556 DUF758 PF05527.6 KFM10770.1 - 5.5e-98 326.0 4.1 6.1e-98 325.9 2.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF758) DUF3877 PF12993.2 KFM10770.1 - 0.0049 16.4 0.6 0.0087 15.6 0.2 1.6 2 0 0 2 2 2 1 Domain of unknown function, E. rectale Gene description (DUF3877) DUF3387 PF11867.3 KFM10770.1 - 0.038 12.9 2.1 0.057 12.3 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3387) Pilus_CpaD PF09476.5 KFM10770.1 - 0.093 12.1 0.0 0.43 10.0 0.0 1.8 2 0 0 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) Pico_P2B PF01552.12 KFM10770.1 - 0.1 12.7 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 Picornavirus 2B protein Perilipin PF03036.11 KFM10771.1 - 2e-111 372.5 17.3 1.4e-110 369.7 12.0 1.8 1 1 0 1 1 1 1 Perilipin family Prefoldin_3 PF13758.1 KFM10771.1 - 0.027 14.2 0.6 0.065 13.0 0.2 1.8 2 0 0 2 2 2 0 Prefoldin subunit Apolipoprotein PF01442.13 KFM10771.1 - 0.029 13.8 22.2 0.22 11.0 2.8 3.6 1 1 2 3 3 3 0 Apolipoprotein A1/A4/E domain YbjQ_1 PF01906.12 KFM10771.1 - 0.029 14.7 3.1 0.05 14.0 0.8 2.2 2 0 0 2 2 2 0 Putative heavy-metal-binding SF-assemblin PF06705.6 KFM10771.1 - 0.032 13.3 0.5 0.28 10.2 0.0 2.2 2 1 0 2 2 2 0 SF-assemblin/beta giardin Phage_GPO PF05929.6 KFM10771.1 - 0.074 12.2 6.9 0.063 12.5 1.5 2.2 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Gp-FAR-1 PF05823.7 KFM10771.1 - 0.1 12.5 2.0 8.1 6.3 0.0 2.9 3 1 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Enkurin PF13864.1 KFM10771.1 - 0.2 11.8 1.9 21 5.4 0.2 3.0 2 1 0 3 3 3 0 Calmodulin-binding PilJ PF13675.1 KFM10771.1 - 0.27 11.5 11.4 1 9.7 0.3 2.9 2 2 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term COG2 PF06148.6 KFM10771.1 - 0.36 10.7 4.0 1 9.2 0.0 3.2 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 FANCI_S4 PF14678.1 KFM10771.1 - 0.37 9.8 2.8 0.28 10.2 0.4 2.0 2 1 0 2 2 2 0 FANCI solenoid 4 TBPIP PF07106.8 KFM10771.1 - 0.45 10.0 5.6 1.1 8.8 1.0 2.8 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ING PF12998.2 KFM10771.1 - 2 8.7 8.5 12 6.1 1.3 3.1 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Carbpep_Y_N PF05388.6 KFM10771.1 - 5.1 7.2 7.8 0.76 9.9 0.3 3.0 3 2 1 4 4 4 0 Carboxypeptidase Y pro-peptide LEDGF PF11467.3 KFM10772.1 - 2.7e-39 133.1 2.7 6.9e-39 131.8 1.8 1.7 1 0 0 1 1 1 1 Lens epithelium-derived growth factor (LEDGF) PWWP PF00855.12 KFM10772.1 - 1.6e-05 24.9 0.0 1.6e-05 24.9 0.0 2.8 3 0 0 3 3 3 1 PWWP domain IncA PF04156.9 KFM10772.1 - 1.7 8.2 6.8 6.1 6.3 4.7 2.0 1 0 0 1 1 1 0 IncA protein PUB PF09409.5 KFM10773.1 - 6.6e-21 73.8 0.3 1.4e-20 72.8 0.2 1.6 1 1 0 1 1 1 1 PUB domain UBX PF00789.15 KFM10773.1 - 4e-09 36.4 0.0 1.1e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 UBX domain PRP21_like_P PF12230.3 KFM10773.1 - 0.95 8.9 9.8 0.03 13.8 1.9 1.9 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein CAF1-p150_C2 PF15539.1 KFM10774.1 - 4.1e-115 383.8 2.4 8.5e-115 382.8 1.6 1.5 1 0 0 1 1 1 1 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term CAF-1_p150 PF11600.3 KFM10774.1 - 1.6e-73 246.6 69.1 1.6e-73 246.6 47.9 2.4 3 0 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal CAF1-p150_N PF15557.1 KFM10774.1 - 4e-28 98.3 6.6 5.8e-28 97.7 3.7 1.9 1 1 0 1 1 1 1 CAF1 complex subunit p150, region binding to PCNA CAF1A PF12253.3 KFM10774.1 - 4e-27 94.1 9.9 4e-27 94.1 6.8 4.6 4 1 0 4 4 4 1 Chromatin assembly factor 1 subunit A Macoilin PF09726.4 KFM10774.1 - 4.2 5.5 36.9 7.7 4.6 25.5 1.4 1 0 0 1 1 1 0 Transmembrane protein BAR PF03114.13 KFM10775.1 - 1.1e-40 139.6 8.3 1.3e-40 139.3 5.8 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 KFM10775.1 - 3.2e-15 55.2 0.1 6.5e-15 54.2 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFM10775.1 - 1.3e-14 53.4 0.1 2.5e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFM10775.1 - 3.3e-13 48.8 0.0 7.5e-13 47.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain BAR_2 PF10455.4 KFM10775.1 - 2e-08 33.5 6.9 2.5e-08 33.2 4.8 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Exonuc_VII_L PF02601.10 KFM10775.1 - 0.0024 17.1 0.4 0.0028 16.8 0.2 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit Fer4_4 PF12800.2 KFM10775.1 - 0.012 15.8 1.3 0.036 14.4 0.9 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain MscS_porin PF12795.2 KFM10775.1 - 0.097 11.9 5.6 0.13 11.5 3.7 1.3 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain Prefoldin_3 PF13758.1 KFM10775.1 - 0.27 11.0 2.7 0.45 10.3 1.9 1.3 1 0 0 1 1 1 0 Prefoldin subunit DUF29 PF01724.11 KFM10775.1 - 0.52 10.1 4.1 0.85 9.4 2.8 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF29 Cadherin PF00028.12 KFM10776.1 - 2.4e-75 248.8 7.4 5.2e-17 61.8 0.0 5.3 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.12 KFM10776.1 - 1.7e-51 174.1 0.6 3.7e-51 173.0 0.4 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.7 KFM10776.1 - 3e-07 29.8 0.1 2.2 7.9 0.0 4.9 4 1 0 4 4 4 3 Cadherin-like DUF4489 PF14879.1 KFM10776.1 - 0.015 15.0 1.3 0.031 13.9 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4489) Cadherin PF00028.12 KFM10777.1 - 9.6e-86 282.1 8.9 9.8e-20 70.6 0.1 5.2 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.12 KFM10777.1 - 1.2e-55 187.6 0.1 2.5e-55 186.6 0.1 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.7 KFM10777.1 - 6.3e-06 25.6 0.0 1.2 8.7 0.0 4.6 4 1 0 4 4 4 2 Cadherin-like 7tm_1 PF00001.16 KFM10778.1 - 6e-38 130.4 26.7 6.4e-36 123.8 18.5 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM10778.1 - 2e-11 43.5 17.1 2e-09 37.0 11.8 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM10778.1 - 0.0038 16.3 14.4 0.0038 16.3 9.9 2.7 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF3278 PF11683.3 KFM10778.1 - 0.013 15.4 3.7 0.013 15.4 2.6 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3278) 7tm_1 PF00001.16 KFM10779.1 - 4.4e-41 140.7 39.1 5.5e-39 133.8 27.1 2.1 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM10779.1 - 8.4e-10 38.2 39.1 1.2e-09 37.7 27.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Pox_MCEL PF03291.11 KFM10780.1 - 2.3e-107 358.7 0.7 2.8e-107 358.4 0.5 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_31 PF13847.1 KFM10780.1 - 1.3e-10 41.0 0.1 3.1e-10 39.8 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFM10780.1 - 3.1e-08 33.5 0.0 6.1e-08 32.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFM10780.1 - 7.8e-07 29.4 0.0 1.4e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFM10780.1 - 5.7e-06 26.8 0.0 1e-05 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFM10780.1 - 7.6e-05 23.1 0.0 0.00014 22.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFM10780.1 - 0.00047 20.4 0.1 0.00092 19.5 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 KFM10780.1 - 0.0081 15.1 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_8 PF05148.10 KFM10780.1 - 0.017 14.7 0.1 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_32 PF13679.1 KFM10780.1 - 0.073 12.7 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF1279 PF06916.8 KFM10781.1 - 1e-25 89.8 0.5 1.9e-25 88.9 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) LEA_4 PF02987.11 KFM10781.1 - 0.0058 16.4 7.4 0.011 15.5 5.1 1.4 1 0 0 1 1 1 1 Late embryogenesis abundant protein Apolipoprotein PF01442.13 KFM10781.1 - 0.021 14.3 0.3 0.035 13.6 0.2 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain YtxH PF12732.2 KFM10781.1 - 0.024 15.0 4.7 0.06 13.7 3.2 1.6 1 0 0 1 1 1 0 YtxH-like protein CAAD PF14159.1 KFM10781.1 - 0.34 10.5 1.4 0.51 10.0 0.1 1.9 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase CD34_antigen PF06365.7 KFM10782.1 - 0.012 15.2 1.3 0.023 14.3 0.9 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family Shisa PF13908.1 KFM10782.1 - 0.03 14.4 0.9 0.03 14.4 0.6 2.2 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator TMEM154 PF15102.1 KFM10782.1 - 0.043 13.5 0.8 0.11 12.1 0.2 1.8 2 0 0 2 2 2 0 TMEM154 protein family Lig_chan PF00060.21 KFM10782.1 - 0.068 12.8 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Ligand-gated ion channel m04gp34like PF12216.3 KFM10782.1 - 0.09 12.1 0.9 0.19 11.0 0.4 1.6 2 0 0 2 2 2 0 Immune evasion protein Motile_Sperm PF00635.21 KFM10783.1 - 7.1e-10 38.4 0.8 0.0011 18.5 0.0 5.3 5 0 0 5 5 5 2 MSP (Major sperm protein) domain MYCBPAP PF14646.1 KFM10783.1 - 3.8e-06 25.8 0.0 0.049 12.3 0.0 3.7 4 0 0 4 4 4 2 MYCBP-associated protein family WD40 PF00400.27 KFM10786.1 - 2.9e-27 93.5 27.6 2.5e-07 30.2 1.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Y_phosphatase PF00102.22 KFM10787.1 - 1.4e-76 256.9 0.1 1.6e-76 256.7 0.0 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFM10787.1 - 0.0049 16.4 0.0 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PAC2 PF09754.4 KFM10788.1 - 2.9e-38 131.9 0.0 3.9e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 PAC2 family YbjN PF10722.4 KFM10788.1 - 0.15 12.1 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative bacterial sensory transduction regulator CEP76-C2 PF15627.1 KFM10789.1 - 2.7e-54 182.9 0.0 5e-54 182.0 0.0 1.5 1 0 0 1 1 1 1 CEP76 C2 domain Transglut_core PF01841.14 KFM10789.1 - 0.0078 16.4 0.1 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily WH2 PF02205.15 KFM10790.1 - 0.09 12.4 1.2 7.3 6.3 0.3 3.7 4 0 0 4 4 4 0 WH2 motif Muted PF14942.1 KFM10790.1 - 0.093 12.6 2.0 13 5.6 0.0 2.6 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein FYVE PF01363.16 KFM10790.1 - 0.4 10.6 14.4 1 9.2 10.0 1.7 1 1 0 1 1 1 0 FYVE zinc finger PRELI PF04707.9 KFM10791.1 - 4.8e-54 182.1 0.1 5.9e-54 181.8 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family PDGLE PF13190.1 KFM10791.1 - 0.026 14.2 0.1 0.079 12.6 0.1 1.7 2 0 0 2 2 2 0 PDGLE domain Peptidase_M41 PF01434.13 KFM10792.1 - 1.1e-73 247.2 1.0 1.1e-73 247.2 0.1 1.5 2 0 0 2 2 1 1 Peptidase family M41 AAA PF00004.24 KFM10792.1 - 1.6e-42 144.8 0.0 3.3e-42 143.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 KFM10792.1 - 2e-10 40.8 0.2 7.8e-10 38.9 0.1 2.1 1 0 0 1 1 1 1 FtsH Extracellular AAA_22 PF13401.1 KFM10792.1 - 0.00014 21.9 0.1 0.009 16.1 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFM10792.1 - 0.00046 19.9 0.0 0.0023 17.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KFM10792.1 - 0.00082 20.1 0.0 0.0031 18.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFM10792.1 - 0.0011 18.6 2.0 0.0053 16.4 0.7 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_2 PF07724.9 KFM10792.1 - 0.0012 18.8 0.0 0.0031 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 KFM10792.1 - 0.0014 17.7 0.1 0.011 14.8 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_14 PF13173.1 KFM10792.1 - 0.0034 17.3 0.0 0.0087 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KFM10792.1 - 0.0036 16.3 0.0 0.0096 14.9 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 KFM10792.1 - 0.0049 15.6 0.0 0.0088 14.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 KFM10792.1 - 0.01 15.8 0.4 0.14 12.1 0.0 2.6 2 1 1 3 3 2 0 AAA ATPase domain IstB_IS21 PF01695.12 KFM10792.1 - 0.013 14.9 0.2 0.027 13.8 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 KFM10792.1 - 0.033 13.5 0.4 0.076 12.4 0.3 1.6 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KFM10792.1 - 0.062 13.1 0.3 0.35 10.7 0.0 2.4 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.16 KFM10792.1 - 0.077 12.1 0.3 0.23 10.6 0.1 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 KFM10792.1 - 0.081 13.2 0.0 0.27 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KFM10792.1 - 0.09 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KFM10792.1 - 0.15 11.3 0.4 0.37 9.9 0.1 1.8 2 0 0 2 2 2 0 PhoH-like protein Tubulin PF00091.20 KFM10793.1 - 4.6e-60 203.1 0.0 7.4e-60 202.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFM10793.1 - 5.3e-49 165.4 0.1 9.4e-49 164.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KFM10793.1 - 0.01 15.3 0.0 0.019 14.4 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain CIDE-N PF02017.10 KFM10794.1 - 3e-32 110.2 0.2 8.6e-32 108.7 0.0 1.8 2 0 0 2 2 2 1 CIDE-N domain DUF1815 PF08844.5 KFM10794.1 - 0.03 13.9 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1815) Inositol_P PF00459.20 KFM10795.1 - 4.4e-74 249.1 0.1 4.9e-74 249.0 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family TMF_DNA_bd PF12329.3 KFM10796.1 - 3.4e-05 23.5 24.9 0.0034 17.1 3.9 3.1 2 1 0 2 2 2 2 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 KFM10796.1 - 0.0019 17.6 3.0 0.0019 17.6 2.0 3.5 2 2 2 4 4 4 1 Septum formation initiator RICH PF05062.7 KFM10796.1 - 0.02 14.9 8.0 0.02 14.9 5.6 2.3 2 0 0 2 2 2 0 RICH domain Myosin_tail_1 PF01576.14 KFM10796.1 - 0.025 12.3 15.1 0.031 12.0 10.5 1.1 1 0 0 1 1 1 0 Myosin tail TMF_TATA_bd PF12325.3 KFM10796.1 - 0.042 13.5 17.3 0.09 12.5 4.0 2.4 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF3510 PF12022.3 KFM10796.1 - 0.045 13.8 0.8 0.045 13.8 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) Ax_dynein_light PF10211.4 KFM10796.1 - 0.047 13.5 17.6 0.057 13.2 4.1 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain CENP-F_leu_zip PF10473.4 KFM10796.1 - 0.084 12.7 17.5 0.91 9.3 4.8 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Peptidase_S64 PF08192.6 KFM10796.1 - 0.091 11.0 3.1 0.12 10.6 2.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 Serpin PF00079.15 KFM10796.1 - 0.092 11.8 1.5 0.1 11.7 1.0 1.2 1 0 0 1 1 1 0 Serpin (serine protease inhibitor) Seryl_tRNA_N PF02403.17 KFM10796.1 - 0.11 12.5 16.3 0.13 12.3 3.8 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4140 PF13600.1 KFM10796.1 - 0.13 12.7 12.1 0.15 12.5 0.4 2.5 2 1 1 3 3 2 0 N-terminal domain of unknown function (DUF4140) CDC37_N PF03234.9 KFM10796.1 - 0.15 12.3 14.6 0.28 11.4 7.5 2.1 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding DUF1664 PF07889.7 KFM10796.1 - 0.25 11.1 6.2 3.8 7.3 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4200 PF13863.1 KFM10796.1 - 0.29 11.0 25.9 0.46 10.4 4.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) Vps54 PF07928.7 KFM10796.1 - 0.36 10.9 0.1 0.36 10.9 0.1 2.0 2 1 1 3 3 2 0 Vps54-like protein PsbQ PF05757.6 KFM10796.1 - 0.41 10.0 5.0 0.21 10.9 0.5 2.2 1 1 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) IncA PF04156.9 KFM10796.1 - 0.48 9.9 21.4 0.84 9.1 5.7 2.1 1 1 1 2 2 2 0 IncA protein HAP1_N PF04849.8 KFM10796.1 - 0.57 9.0 15.5 1.1 8.1 10.7 1.6 1 1 0 1 1 1 0 HAP1 N-terminal conserved region ADIP PF11559.3 KFM10796.1 - 0.68 9.8 20.1 0.36 10.7 4.2 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding APG6 PF04111.7 KFM10796.1 - 0.75 8.7 20.5 0.32 9.9 5.3 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 Filament PF00038.16 KFM10796.1 - 0.82 9.0 17.5 0.13 11.6 3.7 2.1 1 1 1 2 2 2 0 Intermediate filament protein Sec2p PF06428.6 KFM10796.1 - 0.82 9.5 11.1 5.5 6.9 3.2 2.4 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p K-box PF01486.12 KFM10796.1 - 0.86 9.4 16.7 0.06 13.1 3.9 2.5 2 1 0 2 2 2 0 K-box region Herpes_UL6 PF01763.11 KFM10796.1 - 0.93 7.5 12.1 0.69 8.0 6.0 2.1 1 1 1 2 2 2 0 Herpesvirus UL6 like DUF2681 PF10883.3 KFM10796.1 - 1 9.6 0.1 1 9.6 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) MHCassoc_trimer PF08831.5 KFM10796.1 - 1 9.2 4.7 1.7 8.5 0.3 2.7 2 1 1 3 3 3 0 Class II MHC-associated invariant chain trimerisation domain DUF4047 PF13256.1 KFM10796.1 - 1.7 8.6 15.9 0.027 14.4 2.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) GAS PF13851.1 KFM10796.1 - 2 7.5 21.7 34 3.5 5.4 2.2 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.7 KFM10796.1 - 2 8.1 19.9 3.3 7.4 4.4 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.5 KFM10796.1 - 2.1 8.4 12.0 3.7 7.6 1.9 2.9 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Nup54 PF13874.1 KFM10796.1 - 2.3 7.8 13.0 2.8 7.5 3.3 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 IPK PF03770.11 KFM10796.1 - 2.5 7.6 7.6 2.2 7.8 0.7 2.1 2 0 0 2 2 2 0 Inositol polyphosphate kinase DUF972 PF06156.8 KFM10796.1 - 2.9 8.3 17.7 0.68 10.3 4.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) FliD_C PF07195.7 KFM10796.1 - 3 7.0 7.6 9.4 5.4 4.8 1.8 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Phage_GP20 PF06810.6 KFM10796.1 - 3.7 6.9 16.0 1.1 8.6 4.1 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 DUF2458 PF10454.4 KFM10796.1 - 4.1 7.2 17.5 3.1e+02 1.1 11.8 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2458) BLOC1_2 PF10046.4 KFM10796.1 - 4.4 7.5 13.3 5 7.3 2.4 2.6 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mod_r PF07200.8 KFM10796.1 - 4.4 7.1 19.4 2.7 7.9 5.4 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF2205 PF10224.4 KFM10796.1 - 4.7 6.8 13.3 5.6 6.5 1.7 2.6 2 1 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) DivIVA PF05103.8 KFM10796.1 - 5 7.1 17.2 2 8.4 3.9 2.9 1 1 1 2 2 2 0 DivIVA protein DUF2664 PF10867.3 KFM10796.1 - 5.2 7.7 6.5 1.6 9.4 1.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2664) DUF904 PF06005.7 KFM10796.1 - 6.1 7.2 27.2 3.2 8.1 8.3 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF904) Atg14 PF10186.4 KFM10796.1 - 6.3 5.6 20.6 1.6 7.5 4.0 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TBPIP PF07106.8 KFM10796.1 - 6.4 6.2 20.0 2.3 7.7 4.8 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Vps51 PF08700.6 KFM10796.1 - 6.7 6.6 10.4 13 5.6 0.4 3.2 2 2 0 2 2 2 0 Vps51/Vps67 IpaC_SipC PF09599.5 KFM10796.1 - 6.8 5.5 9.5 6.6 5.6 0.4 1.9 1 1 1 2 2 2 0 Salmonella-Shigella invasin protein C (IpaC_SipC) Uds1 PF15456.1 KFM10796.1 - 8 6.4 16.5 2 8.4 1.6 2.8 2 1 0 2 2 2 0 Up-regulated During Septation ATG16 PF08614.6 KFM10796.1 - 9.6 5.9 20.5 9.3 6.0 3.7 2.4 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Metallophos PF00149.23 KFM10797.1 - 1.5e-09 37.5 0.9 2.6e-08 33.4 0.0 2.4 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KFM10797.1 - 1.4e-06 28.2 0.0 2.5e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Varsurf_PPLC PF03490.8 KFM10797.1 - 0.049 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Variant-surface-glycoprotein phospholipase C G-alpha PF00503.15 KFM10798.1 - 2e-93 313.1 6.1 1.5e-92 310.3 4.2 1.9 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KFM10798.1 - 3.2e-12 46.0 1.1 1e-08 34.6 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 KFM10798.1 - 4.8e-05 23.8 0.3 0.15 12.6 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 KFM10798.1 - 0.0014 17.8 1.4 0.13 11.3 0.1 2.5 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 KFM10798.1 - 0.016 14.7 0.2 0.046 13.2 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Bac_luciferase PF00296.15 KFM10798.1 - 0.056 12.5 0.0 0.46 9.5 0.0 2.1 2 0 0 2 2 2 0 Luciferase-like monooxygenase MMR_HSR1 PF01926.18 KFM10798.1 - 0.093 12.6 0.2 3.6 7.5 0.1 2.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF2570 PF10828.3 KFM10798.1 - 0.18 11.3 2.1 0.59 9.7 1.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) SNAP PF14938.1 KFM10800.1 - 2.4e-27 95.8 9.6 3.4e-27 95.3 6.7 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_11 PF13414.1 KFM10800.1 - 4e-05 23.1 12.8 0.19 11.3 0.1 4.6 1 1 4 5 5 5 3 TPR repeat TPR_12 PF13424.1 KFM10800.1 - 9.3e-05 22.2 14.3 0.032 14.1 3.2 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFM10800.1 - 0.00051 20.4 13.2 1.4 9.7 0.7 5.5 2 1 4 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFM10800.1 - 0.008 15.7 6.8 13 5.6 0.1 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat NSF PF02071.15 KFM10800.1 - 0.048 14.1 14.1 0.98 10.2 0.3 5.6 5 0 0 5 5 5 0 Aromatic-di-Alanine (AdAR) repeat DUF2150 PF09920.4 KFM10800.1 - 0.063 12.8 0.3 0.19 11.2 0.1 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2150) Sec5 PF15469.1 KFM10800.1 - 0.074 12.7 0.8 3.7 7.2 0.1 2.3 2 0 0 2 2 2 0 Exocyst complex component Sec5 TPR_5 PF12688.2 KFM10800.1 - 0.18 11.8 3.5 0.35 10.9 0.4 2.3 1 1 1 2 2 2 0 Tetratrico peptide repeat TPR_2 PF07719.12 KFM10800.1 - 0.25 11.3 17.0 3.9 7.6 0.1 6.5 3 2 6 9 9 9 0 Tetratricopeptide repeat UPF0449 PF15136.1 KFM10800.1 - 0.48 10.6 3.5 2.1 8.6 0.1 2.5 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 TPR_16 PF13432.1 KFM10800.1 - 0.69 10.6 19.0 0.21 12.3 2.8 3.9 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFM10800.1 - 8.5 6.8 16.4 3 8.2 1.1 4.1 2 1 1 4 4 4 0 Tetratricopeptide repeat APCDDC PF14921.1 KFM10801.1 - 9.3e-126 418.0 3.4 4.5e-99 330.6 1.1 2.2 2 0 0 2 2 2 2 Adenomatosis polyposis coli down-regulated 1 OMP_b-brl_2 PF13568.1 KFM10801.1 - 0.075 12.8 0.2 0.53 10.0 0.0 2.2 2 1 0 2 2 2 0 Outer membrane protein beta-barrel domain Motile_Sperm PF00635.21 KFM10802.1 - 1.3e-31 108.5 0.2 2e-31 107.8 0.1 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain bZIP_1 PF00170.16 KFM10802.1 - 0.013 15.4 0.6 0.024 14.5 0.4 1.4 1 0 0 1 1 1 0 bZIP transcription factor Rab5-bind PF09311.6 KFM10802.1 - 0.016 15.1 1.4 0.034 14.0 0.6 1.6 2 0 0 2 2 2 0 Rabaptin-like protein DUF972 PF06156.8 KFM10802.1 - 0.024 14.9 0.1 0.049 13.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) K-box PF01486.12 KFM10802.1 - 0.07 12.9 0.2 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 K-box region Ras PF00071.17 KFM10803.1 - 1e-52 177.7 0.0 1.2e-52 177.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM10803.1 - 7.7e-18 65.1 0.0 1.3e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM10803.1 - 6.2e-11 41.8 0.0 7.9e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFM10803.1 - 0.00059 19.3 0.0 0.00075 18.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HEAT PF02985.17 KFM10805.1 - 1.3e-24 84.0 19.8 0.00025 20.8 0.0 10.5 10 0 0 10 10 10 6 HEAT repeat HEAT_2 PF13646.1 KFM10805.1 - 1.9e-15 56.9 4.4 3.5e-05 23.9 0.0 6.2 4 2 4 8 8 8 6 HEAT repeats AF1Q PF15017.1 KFM10805.1 - 6.6e-06 25.9 0.2 6.6e-06 25.9 0.1 2.8 2 1 0 2 2 2 1 Drug resistance and apoptosis regulator HEAT_EZ PF13513.1 KFM10805.1 - 0.09 13.3 5.4 1.6 9.3 0.0 5.0 5 1 1 6 6 6 0 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KFM10805.1 - 0.18 12.2 7.7 6.5 7.2 0.1 5.3 5 2 0 5 5 5 0 Vacuolar 14 Fab1-binding region RhoGAP PF00620.22 KFM10806.1 - 2.8e-43 147.1 0.3 2.8e-43 147.1 0.2 3.2 2 1 1 3 3 3 2 RhoGAP domain DUF948 PF06103.6 KFM10806.1 - 1.5 8.7 8.2 0.24 11.2 1.1 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Tsg PF04668.7 KFM10807.1 - 1.8e-56 189.9 6.3 1.8e-56 189.9 4.4 2.3 2 1 0 2 2 2 1 Twisted gastrulation (Tsg) protein conserved region 2Fe-2S_thioredx PF01257.14 KFM10808.1 - 2.8e-66 221.5 0.1 3.5e-66 221.2 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF1636 PF07845.6 KFM10808.1 - 0.092 12.9 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1636) DUF3166 PF11365.3 KFM10809.1 - 4.8e-60 200.0 30.2 6.5e-42 141.9 1.5 5.2 4 1 1 5 5 5 3 Protein of unknown function (DUF3166) MAD PF05557.8 KFM10809.1 - 0.00096 17.3 9.3 0.00096 17.3 6.5 5.8 3 3 3 6 6 6 4 Mitotic checkpoint protein TPR_MLP1_2 PF07926.7 KFM10809.1 - 0.0013 18.4 35.5 0.017 14.8 1.4 5.3 2 2 2 4 4 4 2 TPR/MLP1/MLP2-like protein TSC22 PF01166.13 KFM10809.1 - 0.0023 17.8 5.8 0.024 14.5 0.2 6.8 7 1 0 7 7 7 3 TSC-22/dip/bun family Fes1 PF08609.5 KFM10809.1 - 0.018 15.4 6.4 1.9 9.0 1.5 3.5 2 1 1 3 3 3 0 Nucleotide exchange factor Fes1 DUF948 PF06103.6 KFM10809.1 - 0.5 10.2 7.2 5.5 6.9 0.0 4.5 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF4201 PF13870.1 KFM10809.1 - 0.88 8.9 51.4 0.37 10.2 1.2 6.6 4 2 2 7 7 7 0 Domain of unknown function (DUF4201) Ras PF00071.17 KFM10810.1 - 2.3e-55 186.4 0.4 2.6e-55 186.2 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM10810.1 - 2e-15 57.3 0.1 3.3e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM10810.1 - 5.6e-14 51.7 0.2 6.6e-14 51.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFM10810.1 - 2e-06 27.3 0.1 2.9e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFM10810.1 - 0.00023 20.3 0.1 0.00024 20.2 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KFM10810.1 - 0.0068 15.6 0.1 0.0091 15.2 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit YTH PF04146.10 KFM10810.1 - 0.046 13.3 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 YT521-B-like domain RIG-I_C-RD PF11648.3 KFM10810.1 - 0.06 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 C-terminal domain of RIG-I Y_phosphatase PF00102.22 KFM10811.1 - 2.3e-153 508.2 0.1 3.7e-86 288.2 0.0 2.4 2 0 0 2 2 2 2 Protein-tyrosine phosphatase MAM PF00629.18 KFM10811.1 - 7.1e-25 87.6 0.0 3.4e-24 85.4 0.0 2.2 2 0 0 2 2 2 1 MAM domain fn3 PF00041.16 KFM10811.1 - 3.7e-24 84.6 13.7 2.3e-09 37.2 0.0 5.7 6 0 0 6 6 5 3 Fibronectin type III domain DSPc PF00782.15 KFM10811.1 - 5.7e-09 35.6 0.1 0.0019 17.7 0.0 2.6 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 KFM10811.1 - 3.4e-05 23.9 0.0 0.017 15.1 0.0 2.8 2 0 0 2 2 2 1 Inositol hexakisphosphate Ig_2 PF13895.1 KFM10811.1 - 4.6e-05 23.4 0.0 0.00013 21.9 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain Y_phosphatase3 PF13350.1 KFM10811.1 - 5.7e-05 23.4 0.0 0.036 14.3 0.0 2.7 2 0 0 2 2 2 1 Tyrosine phosphatase family ig PF00047.20 KFM10811.1 - 0.00025 21.0 0.0 0.005 16.9 0.0 2.8 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.11 KFM10811.1 - 0.00057 19.6 0.0 0.0015 18.3 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.1 KFM10811.1 - 0.0015 18.9 0.0 0.0099 16.3 0.0 2.5 1 0 0 1 1 1 1 Immunoglobulin domain PepSY_TM_3 PF13706.1 KFM10811.1 - 0.016 14.5 0.6 0.035 13.5 0.3 1.7 2 0 0 2 2 2 0 PepSY-associated TM helix TMEM154 PF15102.1 KFM10811.1 - 0.076 12.7 0.1 0.18 11.5 0.1 1.5 1 0 0 1 1 1 0 TMEM154 protein family DctM PF06808.7 KFM10811.1 - 0.081 11.4 0.1 0.12 10.8 0.1 1.1 1 0 0 1 1 1 0 DctM-like transporters LRR_4 PF12799.2 KFM10813.1 - 7.9e-28 95.5 41.1 4.5e-09 35.7 2.3 5.6 3 1 4 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM10813.1 - 2.6e-23 81.5 23.4 1.1e-08 34.6 4.6 4.5 2 2 2 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 KFM10813.1 - 4e-18 62.6 33.0 0.015 15.1 0.0 9.3 9 0 0 9 9 9 7 Leucine Rich Repeat LRR_7 PF13504.1 KFM10813.1 - 4.3e-13 47.1 23.1 0.03 14.4 0.1 9.3 9 0 0 9 9 9 5 Leucine rich repeat LRR_6 PF13516.1 KFM10813.1 - 0.00019 21.1 22.6 0.81 9.9 0.1 8.0 7 1 1 8 8 8 2 Leucine Rich repeat LRR_5 PF13306.1 KFM10813.1 - 0.11 12.1 0.8 0.16 11.6 0.5 1.2 1 0 0 1 1 1 0 Leucine rich repeats (6 copies) Laminin_G_1 PF00054.18 KFM10814.1 - 9.2e-138 452.7 2.9 5.3e-33 113.8 0.0 5.5 5 0 0 5 5 5 5 Laminin G domain Laminin_G_2 PF02210.19 KFM10814.1 - 1.8e-118 390.1 1.0 3.9e-24 85.1 0.0 5.5 5 0 0 5 5 5 5 Laminin G domain Laminin_EGF PF00053.19 KFM10814.1 - 7.2e-112 365.1 343.5 3.6e-10 39.6 8.3 18.8 18 1 0 18 18 18 17 Laminin EGF-like (Domains III and V) Laminin_N PF00055.12 KFM10814.1 - 5.2e-93 310.3 0.0 5.2e-93 310.3 0.0 3.1 4 0 0 4 4 3 1 Laminin N-terminal (Domain VI) Laminin_B PF00052.13 KFM10814.1 - 6.2e-78 259.0 0.4 5.9e-39 132.8 0.0 3.1 3 0 0 3 3 3 2 Laminin B (Domain IV) Laminin_I PF06008.9 KFM10814.1 - 6.4e-43 146.9 18.7 6.4e-43 146.9 13.0 2.7 2 1 1 3 3 3 1 Laminin Domain I Laminin_II PF06009.7 KFM10814.1 - 5.2e-37 126.6 7.9 5.2e-37 126.6 5.5 4.2 4 1 1 5 5 5 2 Laminin Domain II Laminin_G_3 PF13385.1 KFM10814.1 - 1.3e-14 54.6 3.8 1.8e-05 25.0 0.1 4.6 3 1 0 4 4 4 3 Concanavalin A-like lectin/glucanases superfamily Hepar_II_III PF07940.8 KFM10814.1 - 0.0016 18.2 0.0 0.65 9.8 0.0 2.7 2 0 0 2 2 2 1 Heparinase II/III-like protein DUF1080 PF06439.6 KFM10814.1 - 0.017 15.0 0.0 0.72 9.7 0.0 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1080) V_ATPase_I PF01496.14 KFM10814.1 - 0.42 8.3 7.3 0.22 9.3 0.2 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF745 PF05335.8 KFM10814.1 - 4.9 6.6 16.8 0.29 10.6 1.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF745) AKAP7_NLS PF10469.4 KFM10816.1 - 5.4e-46 156.9 0.9 6.2e-46 156.7 0.6 1.0 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.1 KFM10816.1 - 1.1e-07 31.6 0.0 1.5e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.11 KFM10816.1 - 0.00083 19.2 0.1 0.08 12.9 0.0 2.5 2 1 0 2 2 2 1 LigT like Phosphoesterase DsrD PF08679.6 KFM10816.1 - 0.098 12.6 1.1 0.3 11.1 0.0 2.2 2 1 0 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) 4_1_CTD PF05902.8 KFM10817.1 - 6.1e-57 190.6 13.6 6.1e-57 190.6 9.4 2.4 2 0 0 2 2 2 1 4.1 protein C-terminal domain (CTD) SAB PF04382.8 KFM10817.1 - 1.9e-26 91.4 2.7 5.6e-26 89.9 1.9 1.9 1 0 0 1 1 1 1 SAB domain FERM_C PF09380.5 KFM10817.1 - 7.8e-23 80.5 0.0 1.9e-22 79.2 0.0 1.7 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.5 KFM10817.1 - 8e-23 80.2 0.2 9.5e-22 76.8 0.0 2.7 2 0 0 2 2 2 1 FERM N-terminal domain FERM_M PF00373.13 KFM10817.1 - 1.2e-20 73.9 0.0 1.2e-20 73.9 0.0 3.7 3 1 0 4 4 4 1 FERM central domain FA PF08736.6 KFM10817.1 - 1.1e-18 66.7 6.4 3.1e-18 65.2 4.4 1.9 1 0 0 1 1 1 1 FERM adjacent (FA) BTB PF00651.26 KFM10818.1 - 3e-28 98.0 0.9 5.7e-28 97.1 0.6 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.21 KFM10818.1 - 9e-25 85.4 37.6 1.8e-05 24.7 0.1 5.8 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM10818.1 - 2.2e-23 81.3 47.7 2.1e-06 27.7 2.6 6.9 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM10818.1 - 2.5e-19 68.1 27.6 0.0013 18.9 0.1 5.6 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM10818.1 - 3.2e-15 55.7 23.4 0.00093 19.2 0.2 5.8 6 0 0 6 6 5 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM10818.1 - 1.2e-13 50.7 21.5 0.0021 18.1 0.4 5.6 5 0 0 5 5 5 4 Zinc-finger of C2H2 type LIM PF00412.17 KFM10818.1 - 0.022 14.8 19.4 2.1 8.4 2.5 4.4 2 2 2 4 4 4 0 LIM domain zf-C2H2_6 PF13912.1 KFM10818.1 - 0.026 14.4 9.7 0.62 10.0 0.2 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger BTB_2 PF02214.17 KFM10818.1 - 0.051 13.7 0.3 0.19 11.9 0.0 2.1 2 0 0 2 2 2 0 BTB/POZ domain zf-C2HC_2 PF13913.1 KFM10818.1 - 0.065 12.9 5.1 1.5 8.5 0.1 3.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type C1_4 PF07975.7 KFM10818.1 - 0.53 10.3 20.4 4.6 7.3 2.3 4.2 3 1 1 4 4 3 0 TFIIH C1-like domain Elf1 PF05129.8 KFM10818.1 - 1.5 8.6 16.6 0.21 11.3 0.4 3.8 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like zf-CHY PF05495.7 KFM10818.1 - 2 8.6 24.7 1.8 8.7 4.1 3.8 3 2 0 3 3 3 0 CHY zinc finger zf-trcl PF13451.1 KFM10818.1 - 3.3 7.4 12.7 38 4.0 0.1 4.9 5 0 0 5 5 5 0 Probable zinc-binding domain FYDLN_acid PF09538.5 KFM10818.1 - 6.2 7.4 18.0 34 5.0 0.0 4.9 3 2 1 4 4 4 0 Protein of unknown function (FYDLN_acid) AKAP7_RIRII_bdg PF10470.4 KFM10819.1 - 6.1e-06 25.9 2.1 6.9e-06 25.8 1.5 1.1 1 0 0 1 1 1 1 PKA-RI-RII subunit binding domain of A-kinase anchor protein YebO PF13974.1 KFM10819.1 - 2.4 8.0 5.8 2.7 7.8 4.0 1.2 1 0 0 1 1 1 0 YebO-like protein GKAP PF03359.8 KFM10820.1 - 7e-133 443.6 7.6 7e-133 443.6 5.2 2.6 3 1 1 4 4 4 1 Guanylate-kinase-associated protein (GKAP) protein Homeobox_KN PF05920.6 KFM10821.1 - 0.0022 17.6 1.8 0.0039 16.8 1.2 1.4 1 0 0 1 1 1 1 Homeobox KN domain EF-hand_1 PF00036.27 KFM10822.1 - 3.9e-14 50.7 12.9 5.2e-08 31.6 1.1 4.7 6 0 0 6 6 6 3 EF hand EF-hand_7 PF13499.1 KFM10822.1 - 2.5e-12 46.7 7.8 4.7e-07 29.8 0.6 3.0 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 KFM10822.1 - 8e-12 43.9 7.4 6.6e-08 31.8 0.6 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 KFM10822.1 - 1.5e-11 43.7 8.0 4.3e-05 23.0 0.1 4.1 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 KFM10822.1 - 4.2e-06 25.8 2.9 1.4e-05 24.1 0.9 2.6 2 0 0 2 2 2 1 EF hand UPF0154 PF03672.8 KFM10822.1 - 0.00051 19.6 0.0 0.88 9.2 0.0 2.6 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_9 PF14658.1 KFM10822.1 - 0.0034 17.2 0.0 1 9.3 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain DUF1880 PF08976.6 KFM10822.1 - 0.042 13.9 0.0 0.15 12.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) DUF2267 PF10025.4 KFM10822.1 - 0.08 13.0 0.0 3.6 7.6 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2267) SPARC_Ca_bdg PF10591.4 KFM10822.1 - 0.087 12.8 1.1 0.16 12.0 0.3 1.7 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_1 PF00036.27 KFM10824.1 - 3.9e-14 50.7 12.9 5.2e-08 31.6 1.1 4.7 6 0 0 6 6 6 3 EF hand EF-hand_7 PF13499.1 KFM10824.1 - 2.8e-12 46.5 8.0 5e-07 29.7 0.6 3.0 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 KFM10824.1 - 8.1e-12 43.9 7.4 6.6e-08 31.8 0.6 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 KFM10824.1 - 1.5e-11 43.7 8.0 4.3e-05 23.0 0.1 4.1 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 KFM10824.1 - 4.3e-06 25.8 2.9 1.4e-05 24.1 0.9 2.6 2 0 0 2 2 2 1 EF hand UPF0154 PF03672.8 KFM10824.1 - 0.00054 19.5 0.0 0.88 9.2 0.0 2.5 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_9 PF14658.1 KFM10824.1 - 0.0033 17.2 0.0 1 9.3 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain DUF1880 PF08976.6 KFM10824.1 - 0.041 13.9 0.0 0.15 12.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) DUF2267 PF10025.4 KFM10824.1 - 0.075 13.0 0.0 3.6 7.6 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2267) SPARC_Ca_bdg PF10591.4 KFM10824.1 - 0.078 13.0 0.8 0.15 12.0 0.2 1.7 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_1 PF00036.27 KFM10825.1 - 3.9e-14 50.7 12.9 5.2e-08 31.6 1.1 4.7 6 0 0 6 6 6 3 EF hand EF-hand_7 PF13499.1 KFM10825.1 - 2.8e-12 46.5 8.0 5e-07 29.7 0.6 3.0 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 KFM10825.1 - 8.1e-12 43.9 7.4 6.6e-08 31.8 0.6 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 KFM10825.1 - 1.5e-11 43.7 8.0 4.3e-05 23.0 0.1 4.1 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 KFM10825.1 - 4.3e-06 25.8 2.9 1.4e-05 24.1 0.9 2.6 2 0 0 2 2 2 1 EF hand UPF0154 PF03672.8 KFM10825.1 - 0.00054 19.5 0.0 0.88 9.2 0.0 2.5 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_9 PF14658.1 KFM10825.1 - 0.0033 17.2 0.0 1 9.3 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain DUF1880 PF08976.6 KFM10825.1 - 0.041 13.9 0.0 0.15 12.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) DUF2267 PF10025.4 KFM10825.1 - 0.075 13.0 0.0 3.6 7.6 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2267) SPARC_Ca_bdg PF10591.4 KFM10825.1 - 0.078 13.0 0.8 0.15 12.0 0.2 1.7 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region fn3 PF00041.16 KFM10826.1 - 8.3e-79 259.8 0.1 1.4e-15 57.1 0.0 5.7 5 0 0 5 5 5 5 Fibronectin type III domain I-set PF07679.11 KFM10826.1 - 1.6e-73 242.6 13.2 2.2e-20 72.3 0.1 7.9 8 0 0 8 8 8 7 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM10826.1 - 2.9e-36 123.4 0.6 1.5e-08 34.6 0.1 7.1 8 0 0 8 8 8 5 Immunoglobulin domain Ig_3 PF13927.1 KFM10826.1 - 1.5e-19 70.2 5.3 0.003 18.0 0.0 7.0 6 1 0 6 6 6 5 Immunoglobulin domain V-set PF07686.12 KFM10826.1 - 7.6e-19 67.6 15.7 0.00039 20.2 0.4 8.8 7 4 0 7 7 7 5 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM10826.1 - 1.5e-11 44.0 0.4 0.00064 19.5 0.0 4.4 4 0 0 4 4 4 3 CD80-like C2-set immunoglobulin domain ig PF00047.20 KFM10826.1 - 3.2e-11 43.1 13.9 0.13 12.4 0.2 7.2 7 1 0 7 7 7 4 Immunoglobulin domain Herpes_gI PF01688.12 KFM10826.1 - 0.0012 18.0 0.0 5.6 6.0 0.0 3.8 4 0 0 4 4 4 1 Alphaherpesvirus glycoprotein I Tissue_fac PF01108.12 KFM10826.1 - 0.0047 16.6 0.0 1.5 8.6 0.0 3.8 4 0 0 4 4 4 1 Tissue factor Herpes_gE PF02480.11 KFM10826.1 - 0.0053 15.0 0.4 0.054 11.7 0.0 2.8 4 1 0 4 4 4 1 Alphaherpesvirus glycoprotein E LNS2 PF08235.8 KFM10827.1 - 5.5e-69 230.7 0.0 8.3e-69 230.1 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 KFM10827.1 - 3.6e-51 171.4 0.1 8.4e-51 170.3 0.0 1.7 1 0 0 1 1 1 1 lipin, N-terminal conserved region AF1Q PF15017.1 KFM10827.1 - 0.00021 21.1 0.1 0.00021 21.1 0.1 2.4 2 0 0 2 2 2 1 Drug resistance and apoptosis regulator Hydrolase_3 PF08282.7 KFM10827.1 - 0.16 11.5 0.6 1.3 8.5 0.0 2.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Tash_PEST PF07708.6 KFM10827.1 - 3.7 7.6 10.9 0.14 12.1 2.0 2.9 2 0 0 2 2 2 0 Tash protein PEST motif C1q PF00386.16 KFM10828.1 - 2.2e-17 63.2 0.3 1.8e-16 60.2 0.2 2.0 1 1 0 1 1 1 1 C1q domain HATPase_c_3 PF13589.1 KFM10829.1 - 1.5e-14 53.8 0.0 2.6e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KFM10829.1 - 0.00014 21.5 0.0 0.00025 20.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ndc80_HEC PF03801.8 KFM10830.1 - 4.1e-53 179.1 0.0 1.7e-52 177.1 0.0 2.1 1 0 0 1 1 1 1 HEC/Ndc80p family bZIP_1 PF00170.16 KFM10830.1 - 0.0023 17.8 0.9 0.0023 17.8 0.6 5.7 4 2 2 6 6 6 2 bZIP transcription factor IncA PF04156.9 KFM10830.1 - 0.0065 16.0 10.5 0.0065 16.0 7.3 4.0 2 2 1 3 3 3 1 IncA protein LPP PF04728.8 KFM10830.1 - 0.016 15.0 0.4 0.047 13.5 0.0 2.1 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Reo_sigmaC PF04582.7 KFM10830.1 - 0.018 14.2 0.7 0.018 14.2 0.5 2.4 2 1 0 2 2 2 0 Reovirus sigma C capsid protein PRAP PF15314.1 KFM10830.1 - 0.065 13.5 0.6 0.23 11.8 0.4 1.9 1 0 0 1 1 1 0 Proline-rich acidic protein 1, pregnancy-specific uterine Cluap1 PF10234.4 KFM10830.1 - 0.49 9.5 0.0 0.49 9.5 0.0 4.7 3 1 2 5 5 5 0 Clusterin-associated protein-1 HrpB7 PF09486.5 KFM10830.1 - 0.61 9.9 28.4 0.096 12.6 3.1 4.3 3 1 1 4 4 4 0 Bacterial type III secretion protein (HrpB7) SPX PF03105.14 KFM10830.1 - 5.6 6.6 36.5 0.085 12.6 9.8 2.9 2 1 0 2 2 2 0 SPX domain Fringe PF02434.11 KFM10831.1 - 2.4e-11 43.3 0.0 1.7e-10 40.5 0.0 2.0 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.16 KFM10831.1 - 3.1e-08 33.4 0.0 0.0021 17.6 0.0 2.3 1 1 1 2 2 2 2 Galactosyltransferase EF_assoc_2 PF08356.7 KFM10831.1 - 0.026 14.2 0.0 0.072 12.8 0.0 1.6 2 0 0 2 2 2 0 EF hand associated Sulfotransfer_1 PF00685.22 KFM10832.1 - 3.5e-39 134.6 0.4 5.2e-39 134.1 0.3 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 KFM10832.1 - 0.00061 20.7 0.3 0.0017 19.3 0.2 1.9 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.9 KFM10832.1 - 0.00081 19.1 0.9 0.0026 17.4 0.2 1.9 2 0 0 2 2 2 1 Sulfotransferase family Proho_convert PF12177.3 KFM10832.1 - 0.018 14.5 0.1 0.068 12.7 0.0 2.0 1 0 0 1 1 1 0 Prohormone convertase enzyme zf-H2C2_2 PF13465.1 KFM10833.1 - 2e-05 24.6 0.6 2e-05 24.6 0.4 5.8 6 0 0 6 6 6 1 Zinc-finger double domain zf-H2C2_5 PF13909.1 KFM10833.1 - 0.0002 21.3 23.2 0.011 15.8 1.0 4.9 4 0 0 4 4 4 3 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 KFM10833.1 - 0.045 14.0 30.1 1.5 9.3 0.1 5.6 5 0 0 5 5 5 0 Zinc finger, C2H2 type WD40 PF00400.27 KFM10834.1 - 1.2e-66 218.3 12.4 5.1e-11 42.0 0.0 11.2 11 0 0 11 11 11 10 WD domain, G-beta repeat eIF2A PF08662.6 KFM10834.1 - 2.4e-11 43.7 0.3 0.01 15.5 0.0 5.2 2 1 3 5 5 5 4 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.1 KFM10834.1 - 0.00058 19.6 0.0 0.018 14.8 0.0 3.3 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region IKI3 PF04762.7 KFM10834.1 - 0.00087 17.2 0.0 0.065 11.0 0.0 2.8 2 1 0 3 3 3 1 IKI3 family PQQ PF01011.16 KFM10834.1 - 0.0054 16.2 0.3 0.021 14.3 0.0 2.2 2 0 0 2 2 2 1 PQQ enzyme repeat Apc4_WD40 PF12894.2 KFM10834.1 - 0.04 13.4 0.0 1.9 8.0 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Vps5 PF09325.5 KFM10835.1 - 1.7e-85 286.0 19.4 1.7e-85 286.0 13.5 1.4 2 0 0 2 2 2 1 Vps5 C terminal like Sorting_nexin PF03700.8 KFM10835.1 - 1.1e-33 116.0 3.7 2.3e-33 115.0 2.5 1.6 1 0 0 1 1 1 1 Sorting nexin, N-terminal domain PX PF00787.19 KFM10835.1 - 1.2e-30 105.6 0.3 8.4e-29 99.6 0.1 2.6 2 0 0 2 2 2 1 PX domain FAM92 PF06730.6 KFM10835.1 - 0.00059 19.2 7.2 0.0013 18.1 5.0 1.5 1 0 0 1 1 1 1 FAM92 protein SH3BP5 PF05276.9 KFM10835.1 - 0.003 16.9 8.1 0.08 12.2 0.2 2.6 3 0 0 3 3 3 2 SH3 domain-binding protein 5 (SH3BP5) GAS PF13851.1 KFM10835.1 - 0.23 10.6 18.7 0.13 11.4 3.3 2.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Tropomyosin PF00261.15 KFM10835.1 - 0.27 10.2 17.5 0.019 14.0 2.8 2.4 2 0 0 2 2 2 0 Tropomyosin DUF3138 PF11336.3 KFM10835.1 - 0.3 9.2 3.8 0.45 8.6 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Spc7 PF08317.6 KFM10835.1 - 0.41 9.2 17.1 0.17 10.5 3.2 2.5 2 1 0 2 2 2 0 Spc7 kinetochore protein HR1 PF02185.11 KFM10835.1 - 0.61 9.8 11.0 2.2 8.1 0.1 3.6 3 0 0 3 3 3 0 Hr1 repeat Reo_sigmaC PF04582.7 KFM10835.1 - 0.67 9.0 3.0 0.57 9.3 0.6 1.7 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF4618 PF15397.1 KFM10835.1 - 1.8 7.7 13.8 1.1 8.5 1.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4618) DUF848 PF05852.6 KFM10835.1 - 2.7 7.8 14.3 0.52 10.1 3.5 2.6 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Allexi_40kDa PF05549.6 KFM10835.1 - 3.8 6.7 8.3 0.59 9.3 0.6 2.6 2 1 1 3 3 3 0 Allexivirus 40kDa protein GrpE PF01025.14 KFM10835.1 - 5.4 6.5 19.1 0.11 11.9 4.0 2.6 2 1 0 2 2 2 0 GrpE PX PF00787.19 KFM10836.1 - 6e-14 51.8 3.6 1.7e-13 50.3 1.9 1.8 1 1 1 2 2 2 2 PX domain Pro_isomerase PF00160.16 KFM10837.1 - 1e-45 155.7 0.2 1.2e-45 155.4 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-H2C2_2 PF13465.1 KFM10838.1 - 1.3e-13 50.4 13.6 5.6e-05 23.2 0.1 4.8 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 KFM10838.1 - 2.6e-12 46.3 19.6 5.4e-05 23.2 1.0 4.3 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM10838.1 - 1.1e-10 41.0 13.7 0.0016 18.6 1.0 4.4 3 0 0 3 3 3 3 C2H2-type zinc finger SET PF00856.23 KFM10838.1 - 2.6e-07 31.0 0.1 3.4e-06 27.4 0.1 2.4 1 1 0 1 1 1 1 SET domain zf-C2H2_jaz PF12171.3 KFM10838.1 - 0.0014 18.6 0.6 0.038 14.1 0.0 2.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 KFM10838.1 - 0.0034 17.5 3.7 0.012 15.7 1.4 2.6 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 KFM10838.1 - 0.013 15.4 9.3 0.64 9.9 0.2 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-BED PF02892.10 KFM10838.1 - 0.14 11.9 4.8 0.72 9.6 0.1 3.1 3 0 0 3 3 3 0 BED zinc finger zf-C2HC_2 PF13913.1 KFM10838.1 - 0.32 10.7 0.0 0.32 10.7 0.0 3.8 4 0 0 4 4 4 0 zinc-finger of a C2HC-type SprT-like PF10263.4 KFM10838.1 - 0.54 9.8 5.4 1.7 8.2 2.3 2.5 2 1 0 2 2 2 0 SprT-like family zf-CHCC PF10276.4 KFM10838.1 - 1.4 8.8 5.2 0.71 9.7 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger domain zf-Di19 PF05605.7 KFM10838.1 - 3.7 7.7 13.1 2 8.6 0.0 3.8 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DUF3668 PF12416.3 KFM10839.1 - 1e-127 426.0 2.1 1.8e-127 425.2 0.0 2.4 3 1 1 4 4 4 1 Cep120 protein Pkinase PF00069.20 KFM10840.1 - 1.4e-34 119.4 0.0 1.8e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain CK1gamma_C PF12605.3 KFM10840.1 - 1.7e-22 79.8 6.5 3e-22 78.9 4.5 1.4 1 0 0 1 1 1 1 Casein kinase 1 gamma C terminal Pkinase_Tyr PF07714.12 KFM10840.1 - 1.2e-13 50.6 0.0 1.6e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RVT_1 PF00078.22 KFM10842.1 - 0.012 14.9 0.0 0.031 13.6 0.0 1.6 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Yae1_N PF09811.4 KFM10843.1 - 4.5e-15 54.8 40.0 8.9e+02 -0.5 27.7 4.0 1 1 0 1 1 1 0 Essential protein Yae1, N terminal GRAM PF02893.15 KFM10844.1 - 7.5e-14 51.0 0.2 1.5e-13 50.0 0.1 1.5 1 0 0 1 1 1 1 GRAM domain DUF1724 PF08350.5 KFM10844.1 - 0.057 12.9 0.0 0.15 11.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1724) Aldedh PF00171.17 KFM10845.1 - 4.6e-124 414.2 0.0 5.1e-124 414.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OmdA PF13376.1 KFM10845.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated Ank_2 PF12796.2 KFM10846.1 - 3.5e-74 245.1 14.9 4.7e-24 84.5 0.6 5.3 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KFM10846.1 - 8.9e-61 198.8 15.2 4.4e-08 32.5 0.0 8.9 8 0 0 8 8 8 8 Ankyrin repeat Ank_3 PF13606.1 KFM10846.1 - 1.9e-43 142.1 12.6 5.5e-07 29.2 0.0 10.2 9 1 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.1 KFM10846.1 - 6.2e-42 141.2 6.2 7.7e-10 39.0 0.0 7.2 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM10846.1 - 1.9e-40 135.9 11.2 2.1e-09 37.2 0.2 8.2 4 2 5 9 9 9 7 Ankyrin repeats (many copies) TPR_12 PF13424.1 KFM10846.1 - 1.7e-05 24.6 0.1 0.009 15.9 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFM10846.1 - 0.018 14.9 0.7 0.36 10.8 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 KFM10846.1 - 0.062 13.2 0.1 0.53 10.3 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat NPV_P10 PF05531.7 KFM10847.1 - 0.16 12.1 6.5 0.056 13.7 2.4 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 KFM10847.1 - 0.21 11.4 5.0 0.23 11.3 1.9 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-B_box PF00643.19 KFM10848.1 - 3.2e-07 30.1 7.0 3.2e-07 30.1 4.8 4.6 4 1 0 4 4 4 2 B-box zinc finger SPRY PF00622.23 KFM10848.1 - 8.6e-07 29.0 0.0 2.5e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 SPRY domain zf-C3HC4 PF00097.20 KFM10848.1 - 1.1e-05 24.9 5.0 1.1e-05 24.9 3.5 3.7 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFM10848.1 - 2e-05 24.3 4.9 2e-05 24.3 3.4 3.5 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 KFM10848.1 - 7.6e-05 22.6 5.3 7.6e-05 22.6 3.7 3.7 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) fn3 PF00041.16 KFM10848.1 - 0.00012 22.1 0.1 0.00025 21.1 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain zf-C3HC4_3 PF13920.1 KFM10848.1 - 0.00075 19.1 4.0 0.00075 19.1 2.7 4.3 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFM10848.1 - 0.00082 19.0 5.8 0.00082 19.0 4.0 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 KFM10848.1 - 0.0021 17.7 4.6 0.0021 17.7 3.2 4.2 3 1 1 4 4 4 1 zinc-RING finger domain Mss4 PF04421.8 KFM10848.1 - 0.28 11.0 3.6 0.85 9.5 2.5 1.9 1 0 0 1 1 1 0 Mss4 protein CaMBD PF02888.11 KFM10849.1 - 6.3e-36 122.0 9.2 6.3e-36 122.0 6.4 2.1 2 0 0 2 2 2 1 Calmodulin binding domain SK_channel PF03530.9 KFM10849.1 - 1.3e-35 121.7 0.9 1.3e-35 121.7 0.6 2.2 2 0 0 2 2 2 1 Calcium-activated SK potassium channel Ion_trans_2 PF07885.11 KFM10849.1 - 6.1e-13 48.2 3.9 6.1e-13 48.2 2.7 2.0 2 0 0 2 2 2 1 Ion channel Med9 PF07544.8 KFM10849.1 - 0.0063 16.2 0.2 0.014 15.1 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Prefoldin_2 PF01920.15 KFM10849.1 - 1.3 8.7 11.6 9.1 6.1 4.6 3.2 1 1 1 2 2 2 0 Prefoldin subunit Yae1_N PF09811.4 KFM10851.1 - 2.6e-10 39.6 26.6 0.087 12.3 18.4 3.1 1 1 0 1 1 1 1 Essential protein Yae1, N terminal YTH PF04146.10 KFM10852.1 - 5.3e-46 155.7 0.1 5.3e-46 155.7 0.1 1.9 2 0 0 2 2 1 1 YT521-B-like domain HA2 PF04408.18 KFM10852.1 - 9e-20 70.6 1.3 1.3e-19 70.0 0.0 2.0 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KFM10852.1 - 5.8e-12 45.4 0.0 1.5e-11 44.0 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 KFM10852.1 - 4.3e-11 42.6 0.2 9.1e-11 41.5 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFM10852.1 - 7.1e-11 41.8 0.0 1.9e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ank_2 PF12796.2 KFM10852.1 - 3.5e-10 40.0 0.0 8.7e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFM10852.1 - 2.4e-05 23.9 0.0 0.0074 16.0 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat AAA_22 PF13401.1 KFM10852.1 - 8.6e-05 22.6 0.2 0.00041 20.4 0.1 2.3 2 1 0 2 2 1 1 AAA domain KaiC PF06745.8 KFM10852.1 - 0.00082 18.5 0.0 0.0016 17.5 0.0 1.4 1 0 0 1 1 1 1 KaiC Ank_4 PF13637.1 KFM10852.1 - 0.0032 17.9 0.0 0.034 14.6 0.0 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM10852.1 - 0.0043 17.2 0.0 0.011 15.9 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) PhoH PF02562.11 KFM10852.1 - 0.0049 16.1 0.0 0.0089 15.2 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein AAA_23 PF13476.1 KFM10852.1 - 0.011 16.1 3.1 0.023 15.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 KFM10852.1 - 0.012 14.4 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 KFM10852.1 - 0.016 14.7 0.0 0.043 13.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KFM10852.1 - 0.025 14.0 0.0 0.052 13.0 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family SRP54 PF00448.17 KFM10852.1 - 0.048 13.0 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_19 PF13245.1 KFM10852.1 - 0.061 13.0 0.8 0.26 11.0 0.0 2.5 3 0 0 3 3 3 0 Part of AAA domain MCC-bdg_PDZ PF10506.4 KFM10853.1 - 2e-59 197.2 40.1 7.6e-29 99.3 4.8 6.4 6 0 0 6 6 6 3 PDZ domain of MCC-2 bdg protein for Usher syndrome ERM PF00769.14 KFM10853.1 - 0.00019 21.0 71.6 0.00056 19.5 6.9 5.2 4 2 0 4 4 4 2 Ezrin/radixin/moesin family APG6 PF04111.7 KFM10853.1 - 0.011 14.7 0.8 0.011 14.7 0.6 5.7 4 1 1 5 5 5 0 Autophagy protein Apg6 DUF1359 PF07097.6 KFM10853.1 - 0.11 12.5 7.7 1 9.4 0.0 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1359) Myosin_tail_1 PF01576.14 KFM10853.1 - 5.2 4.6 78.7 0.049 11.3 11.3 4.4 3 1 1 4 4 4 0 Myosin tail DCP2 PF05026.8 KFM10854.1 - 3.6e-26 90.8 0.3 6.6e-25 86.8 0.1 2.5 2 0 0 2 2 2 1 Dcp2, box A domain NUDIX PF00293.23 KFM10854.1 - 6.3e-16 58.2 0.0 1.7e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain TB2_DP1_HVA22 PF03134.14 KFM10855.1 - 4.5e-37 125.6 1.5 6.1e-37 125.2 1.1 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family SRP19 PF01922.12 KFM10856.1 - 6.7e-26 90.6 0.1 8.1e-26 90.4 0.0 1.1 1 0 0 1 1 1 1 SRP19 protein APC_basic PF05956.6 KFM10857.1 - 7.4e-111 370.7 73.5 7.4e-111 370.7 50.9 7.1 8 1 0 8 8 8 1 APC basic domain EB1_binding PF05937.6 KFM10857.1 - 4.3e-85 284.4 21.7 4.3e-85 284.4 15.0 7.8 7 2 0 9 9 9 1 EB-1 Binding Domain APC_crr PF05923.7 KFM10857.1 - 1.1e-64 211.7 54.0 2.8e-11 42.5 1.4 9.8 9 0 0 9 9 9 7 APC cysteine-rich region Arm PF00514.18 KFM10857.1 - 3.6e-30 102.7 14.3 3.2e-07 29.9 0.3 6.9 6 0 0 6 6 6 6 Armadillo/beta-catenin-like repeat SAMP PF05924.6 KFM10857.1 - 6.1e-28 94.8 10.3 1.7e-09 36.3 0.7 4.0 3 0 0 3 3 3 3 SAMP Motif Suppressor_APC PF11414.3 KFM10857.1 - 6.1e-28 96.4 6.1 6.1e-28 96.4 4.2 2.8 2 0 0 2 2 2 1 Adenomatous polyposis coli tumour suppressor protein APC_15aa PF05972.6 KFM10857.1 - 8e-24 81.9 27.9 2.2e-06 27.2 0.1 5.9 6 0 0 6 6 6 4 APC 15 residue motif HALZ PF02183.13 KFM10857.1 - 0.69 9.6 12.5 0.038 13.7 1.8 3.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper FERM_M PF00373.13 KFM10858.1 - 3.7e-21 75.6 1.6 5.2e-21 75.1 0.0 2.1 2 0 0 2 2 2 1 FERM central domain FERM_C PF09380.5 KFM10858.1 - 1.3e-17 63.8 0.6 2.5e-17 62.8 0.4 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.5 KFM10858.1 - 1.6e-17 63.3 0.1 7.9e-17 61.0 0.0 2.2 3 0 0 3 3 3 1 FERM N-terminal domain FA PF08736.6 KFM10858.1 - 3.7e-12 45.8 2.2 3.7e-12 45.8 1.6 3.1 3 0 0 3 3 3 1 FERM adjacent (FA) Alveol-reg_P311 PF11092.3 KFM10859.1 - 1.4e-33 114.7 0.2 1.5e-33 114.5 0.1 1.0 1 0 0 1 1 1 1 Neuronal protein 3.1 (p311) START PF01852.14 KFM10860.1 - 3.5e-16 59.1 0.0 3.8e-16 59.0 0.0 1.0 1 0 0 1 1 1 1 START domain Pkinase PF00069.20 KFM10861.1 - 7.6e-46 156.3 0.0 8.5e-46 156.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM10861.1 - 1.9e-15 56.6 0.0 2.1e-15 56.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM10861.1 - 0.0018 17.3 0.0 0.0022 17.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Utp21 PF04192.7 KFM10862.1 - 4.8e-70 235.3 0.0 6.8e-70 234.8 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 KFM10862.1 - 4.7e-28 96.0 9.4 1e-10 41.0 0.5 8.7 9 0 0 9 9 9 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KFM10862.1 - 0.011 14.5 1.7 3.1 6.4 0.1 3.3 2 2 1 3 3 3 0 Nup133 N terminal like Cytochrom_D1 PF02239.11 KFM10862.1 - 0.018 13.3 0.0 0.033 12.5 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain Utp12 PF04003.7 KFM10862.1 - 0.086 12.7 4.4 0.14 12.0 2.4 1.8 2 0 0 2 2 2 0 Dip2/Utp12 Family SGL PF08450.7 KFM10862.1 - 0.11 11.8 0.0 0.48 9.7 0.0 2.0 3 0 0 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region Mito_carr PF00153.22 KFM10863.1 - 7.4e-20 70.4 0.1 7.8e-12 44.7 0.0 2.7 2 0 0 2 2 2 2 Mitochondrial carrier protein Glyco_hydro_38 PF01074.17 KFM10865.1 - 4.3e-98 327.9 5.1 7.3e-98 327.1 3.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 KFM10865.1 - 1.1e-61 209.0 0.5 1.9e-61 208.3 0.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 KFM10865.1 - 3.7e-26 91.1 0.0 8.1e-26 90.0 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase, middle domain zf-RING_2 PF13639.1 KFM10866.1 - 8.5e-11 41.5 14.9 1.8e-10 40.4 10.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFM10866.1 - 8.3e-07 28.9 11.4 1.7e-06 27.9 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM10866.1 - 3e-06 26.7 11.3 8e-06 25.4 7.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFM10866.1 - 1.6e-05 24.9 10.3 3.7e-05 23.7 7.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KFM10866.1 - 0.00017 21.1 11.2 0.00037 20.0 7.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM10866.1 - 0.0013 18.4 13.3 0.0027 17.3 9.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KFM10866.1 - 0.0021 17.8 6.8 0.0043 16.8 4.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Amidase PF01425.16 KFM10866.1 - 0.057 12.2 0.0 0.09 11.6 0.0 1.2 1 0 0 1 1 1 0 Amidase Pkinase_Tyr PF07714.12 KFM10868.1 - 2.2e-102 341.6 0.3 8.2e-102 339.7 0.0 2.1 2 1 1 3 3 3 1 Protein tyrosine kinase Pkinase PF00069.20 KFM10868.1 - 2.1e-53 181.1 0.0 7.2e-53 179.3 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 KFM10868.1 - 2.4e-22 78.5 0.0 8e-22 76.8 0.0 2.0 1 0 0 1 1 1 1 SH2 domain FCH PF00611.18 KFM10868.1 - 4e-17 62.1 1.3 4e-17 62.1 0.9 3.7 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain LRR_6 PF13516.1 KFM10869.1 - 2.8e-15 54.5 7.2 1.2 9.4 0.1 10.4 11 0 0 11 11 11 2 Leucine Rich repeat LRR_4 PF12799.2 KFM10869.1 - 1.7e-07 30.7 5.0 0.25 11.0 0.0 6.1 4 3 3 7 7 7 2 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KFM10869.1 - 7.7e-07 28.7 3.4 7.7e-07 28.7 2.3 1.9 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 KFM10869.1 - 3e-05 23.6 4.9 0.13 12.0 0.9 4.9 4 1 1 5 5 5 2 Leucine rich repeat F-box PF00646.28 KFM10869.1 - 0.0019 17.7 5.4 0.002 17.7 1.6 2.8 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.28 KFM10869.1 - 0.064 13.3 10.1 13 6.2 0.0 6.6 5 2 0 5 5 5 0 Leucine Rich Repeat LRR_7 PF13504.1 KFM10869.1 - 0.079 13.1 10.7 2 8.9 0.0 5.9 5 1 0 5 5 5 0 Leucine rich repeat Aldedh PF00171.17 KFM10869.1 - 0.13 10.5 0.0 0.27 9.5 0.0 1.4 2 0 0 2 2 2 0 Aldehyde dehydrogenase family Ephrin PF00812.12 KFM10870.1 - 7.5e-47 158.4 0.2 9.3e-47 158.1 0.1 1.1 1 0 0 1 1 1 1 Ephrin PRESAN PF09687.5 KFM10872.1 - 0.0043 17.1 2.0 0.042 13.9 0.0 2.2 1 1 0 1 1 1 1 Plasmodium RESA N-terminal LON PF02190.11 KFM10872.1 - 0.025 14.2 0.0 0.028 14.0 0.0 1.1 1 0 0 1 1 1 0 ATP-dependent protease La (LON) domain DUF2973 PF11189.3 KFM10872.1 - 0.027 14.2 0.0 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) FKBP_N PF01346.13 KFM10872.1 - 0.12 12.4 1.9 3 7.8 1.4 2.2 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase NUDIX PF00293.23 KFM10873.1 - 5.1e-17 61.7 0.0 1.5e-16 60.2 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain Ank_2 PF12796.2 KFM10873.1 - 5.2e-10 39.5 0.1 1.4e-09 38.1 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFM10873.1 - 6.2e-09 35.8 0.1 1.4e-08 34.6 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 KFM10873.1 - 1.3e-08 34.2 0.0 4.7e-07 29.2 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 KFM10873.1 - 3.3e-08 33.8 1.1 0.00039 20.8 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) zf-NADH-PPase PF09297.6 KFM10873.1 - 7.4e-08 31.7 0.6 1.3e-07 30.9 0.4 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain NUDIX-like PF09296.6 KFM10873.1 - 2.6e-07 30.8 0.0 4.6e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain Ank_3 PF13606.1 KFM10873.1 - 1.4e-06 27.9 0.9 1.8e-05 24.5 0.0 3.2 4 0 0 4 4 4 1 Ankyrin repeat PH PF00169.24 KFM10874.1 - 1.8e-25 89.1 0.2 7.3e-15 55.0 0.0 2.6 3 0 0 3 3 3 2 PH domain PDZ PF00595.19 KFM10874.1 - 5.4e-14 52.1 0.0 9.4e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PH_11 PF15413.1 KFM10874.1 - 3.7e-11 43.2 9.9 3e-06 27.4 2.9 4.3 2 2 1 3 3 3 2 Pleckstrin homology domain PH_8 PF15409.1 KFM10874.1 - 1.5e-07 31.3 0.8 4e-06 26.7 0.4 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain PDZ_2 PF13180.1 KFM10874.1 - 2e-07 30.7 0.0 4.2e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PH_9 PF15410.1 KFM10874.1 - 0.0042 17.2 0.6 3 8.0 0.0 3.5 2 2 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.1 KFM10874.1 - 0.019 14.8 0.1 0.27 11.1 0.0 2.4 2 0 0 2 2 2 0 PH domain UNC119_bdg PF15435.1 KFM10875.1 - 4.7e-112 372.0 0.4 5.3e-112 371.8 0.3 1.0 1 0 0 1 1 1 1 UNC119-binding protein C5orf30 homologue His_Phos_2 PF00328.17 KFM10876.1 - 2.5e-109 365.7 1.2 3.3e-109 365.4 0.8 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 KFM10876.1 - 0.00013 21.4 0.0 0.00029 20.3 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain His_Phos_1 PF00300.17 KFM10876.1 - 0.018 15.1 0.1 0.086 12.9 0.0 2.2 3 0 0 3 3 3 0 Histidine phosphatase superfamily (branch 1) rve PF00665.21 KFM10877.1 - 1.1e-11 44.8 0.0 1.2e-10 41.5 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.5 KFM10877.1 - 0.00015 21.0 3.6 0.0004 19.7 2.5 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger FANCAA PF15146.1 KFM10877.1 - 0.04 12.8 0.0 0.067 12.0 0.0 1.3 1 0 0 1 1 1 0 Fanconi anemia-associated Pox_A3L PF05288.6 KFM10877.1 - 0.1 12.3 1.7 0.15 11.8 0.1 2.1 3 0 0 3 3 3 0 Poxvirus A3L Protein Cu2_monoox_C PF03712.10 KFM10878.1 - 1.3e-49 167.5 0.8 2.1e-49 166.9 0.2 1.6 2 0 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.15 KFM10878.1 - 4.8e-32 110.7 0.0 1e-31 109.6 0.0 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain NHL PF01436.16 KFM10878.1 - 5.7e-27 92.2 7.3 3.8e-07 29.7 0.0 6.2 6 0 0 6 6 6 4 NHL repeat SGL PF08450.7 KFM10878.1 - 0.1 11.9 0.0 14 4.9 0.0 2.8 3 0 0 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region OATP PF03137.15 KFM10879.1 - 3.5e-24 84.7 0.2 5.1e-24 84.2 0.1 1.3 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Kelch_1 PF01344.20 KFM10880.1 - 5.8e-29 99.3 17.4 1.1e-09 37.6 0.2 7.6 6 2 0 6 6 6 5 Kelch motif BACK PF07707.10 KFM10880.1 - 1.2e-28 98.8 0.2 2.9e-28 97.7 0.0 1.7 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.26 KFM10880.1 - 5.6e-28 97.1 0.0 1e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.1 KFM10880.1 - 1.2e-26 91.7 13.0 1.2e-06 28.4 0.0 6.7 3 2 3 6 6 6 6 Kelch motif Kelch_2 PF07646.10 KFM10880.1 - 9e-15 53.7 3.2 0.24 11.2 0.0 6.8 7 0 0 7 7 7 5 Kelch motif Kelch_3 PF13415.1 KFM10880.1 - 8.2e-10 38.5 9.7 3.3e-06 27.0 0.5 5.6 4 2 1 5 5 5 2 Galactose oxidase, central domain Kelch_4 PF13418.1 KFM10880.1 - 1.2e-08 34.5 11.1 0.043 13.5 0.5 6.8 6 3 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.1 KFM10880.1 - 1.2e-06 28.3 4.1 0.0023 17.8 0.0 3.7 4 0 0 4 4 4 2 Kelch motif PP2C PF00481.16 KFM10881.1 - 4e-63 213.1 0.2 4.9e-63 212.8 0.2 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KFM10881.1 - 3.2e-06 26.6 0.0 5.5e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C DUF3536 PF12055.3 KFM10881.1 - 0.098 11.8 0.1 0.3 10.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3536) Mab-21 PF03281.9 KFM10882.1 - 1e-17 64.2 0.0 1.5e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Mab-21 protein EGF PF00008.22 KFM10883.1 - 3.4e-75 247.3 216.3 6.5e-08 32.3 5.9 14.7 14 0 0 14 14 14 13 EGF-like domain fn3 PF00041.16 KFM10883.1 - 3.1e-35 120.1 5.1 4.2e-13 49.2 0.7 3.4 3 0 0 3 3 3 3 Fibronectin type III domain NIDO PF06119.9 KFM10883.1 - 1.9e-31 108.5 0.1 4e-31 107.5 0.0 1.6 1 0 0 1 1 1 1 Nidogen-like EGF_CA PF07645.10 KFM10883.1 - 4.2e-25 87.4 200.4 4.5e-09 36.1 5.1 14.7 8 5 6 14 14 14 10 Calcium-binding EGF domain EGF_2 PF07974.8 KFM10883.1 - 1.3e-20 73.1 243.3 0.0034 17.5 6.6 14.4 14 0 0 14 14 14 13 EGF-like domain hEGF PF12661.2 KFM10883.1 - 3.7e-16 57.9 143.6 0.0049 16.8 1.1 15.5 16 0 0 16 16 16 10 Human growth factor-like EGF EGF_3 PF12947.2 KFM10883.1 - 0.00055 19.8 14.6 0.0016 18.3 3.0 14.8 12 1 2 14 14 14 4 EGF domain cEGF PF12662.2 KFM10883.1 - 0.0015 18.0 1.1 0.0015 18.0 0.8 16.1 15 2 0 15 15 15 7 Complement Clr-like EGF-like Pkinase PF00069.20 KFM10884.1 - 7.5e-58 195.7 0.0 3.8e-57 193.3 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM10884.1 - 4.3e-23 81.7 0.0 7.1e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PAS_9 PF13426.1 KFM10884.1 - 6.6e-11 42.5 0.0 8.7e-05 22.8 0.0 4.0 4 0 0 4 4 4 2 PAS domain PAS PF00989.19 KFM10884.1 - 5.4e-10 39.0 0.0 2.6e-06 27.1 0.0 3.7 4 0 0 4 4 4 2 PAS fold PAS_8 PF13188.1 KFM10884.1 - 3.7e-05 23.4 0.0 0.0009 19.0 0.0 2.8 2 0 0 2 2 2 1 PAS domain Kinase-like PF14531.1 KFM10884.1 - 8.1e-05 21.7 0.0 0.0003 19.8 0.0 2.1 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFM10884.1 - 0.077 12.0 0.0 0.17 10.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_4 PF12799.2 KFM10885.1 - 1e-39 133.5 62.6 3.1e-10 39.4 2.1 6.2 3 1 4 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM10885.1 - 1.4e-25 88.8 67.0 1.6e-08 34.1 5.9 4.8 2 1 4 6 6 6 6 Leucine rich repeat LRR_9 PF14580.1 KFM10885.1 - 2e-19 69.8 22.2 2.8e-08 33.4 3.8 4.0 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.28 KFM10885.1 - 2.8e-12 44.8 40.2 0.084 12.9 0.2 10.9 11 0 0 11 11 11 6 Leucine Rich Repeat LRR_6 PF13516.1 KFM10885.1 - 1.1e-08 34.2 32.7 0.095 12.8 0.3 10.3 7 4 3 10 10 10 3 Leucine Rich repeat LRR_7 PF13504.1 KFM10885.1 - 8e-08 31.2 24.8 0.61 10.5 0.1 9.9 9 2 1 10 10 10 3 Leucine rich repeat UB2H PF14814.1 KFM10885.1 - 0.34 10.6 9.5 39 4.0 0.0 5.3 2 2 3 6 6 6 0 Bifunctional transglycosylase second domain Anoctamin PF04547.7 KFM10886.1 - 2.1e-142 474.9 20.2 2.6e-142 474.6 14.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel MMPL PF03176.10 KFM10886.1 - 5.9 5.4 8.2 9.4 4.8 5.7 1.3 1 0 0 1 1 1 0 MMPL family KH_1 PF00013.24 KFM10887.1 - 2.2e-186 603.7 62.9 2.7e-15 55.7 1.3 15.8 15 1 0 15 15 15 15 KH domain KH_3 PF13014.1 KFM10887.1 - 9.3e-130 420.8 57.1 3.4e-12 45.7 0.9 15.6 16 0 0 16 16 16 14 KH domain SLS PF14611.1 KFM10887.1 - 2e-24 86.1 19.4 7.5e-07 28.7 0.1 8.6 3 3 6 9 9 9 6 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.12 KFM10887.1 - 6.8e-15 54.4 51.9 0.0095 15.4 1.1 12.3 10 3 1 12 12 12 8 KH domain BMC PF00936.14 KFM10887.1 - 6.8e-10 38.4 4.1 3 7.5 0.0 9.8 11 0 0 11 11 11 1 BMC domain KH_5 PF13184.1 KFM10887.1 - 1.1e-07 31.5 25.8 2.3 8.1 0.0 11.2 13 0 0 13 13 13 4 NusA-like KH domain DUF2096 PF09869.4 KFM10887.1 - 1.5e-05 24.9 21.3 2.8 7.7 0.0 9.4 10 1 1 11 11 11 3 Uncharacterized protein conserved in archaea (DUF2096) Lactamase_B_4 PF13691.1 KFM10887.1 - 0.0084 15.5 0.0 10 5.6 0.0 3.7 3 0 0 3 3 3 1 tRNase Z endonuclease SCO1-SenC PF02630.9 KFM10887.1 - 0.074 12.6 2.1 5.2 6.6 0.1 3.3 2 0 0 2 2 2 0 SCO1/SenC Septin PF00735.13 KFM10888.1 - 1.6e-126 421.0 0.1 1.9e-126 420.8 0.1 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KFM10888.1 - 1.5e-07 31.3 0.0 3.9e-07 30.0 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFM10888.1 - 6.7e-06 25.6 0.1 0.0015 18.0 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KFM10888.1 - 5e-05 23.1 0.1 0.021 14.6 0.0 2.8 1 1 1 2 2 2 1 Dynamin family AIG1 PF04548.11 KFM10888.1 - 0.00011 21.3 0.2 0.00031 19.9 0.0 1.8 2 0 0 2 2 2 1 AIG1 family DUF258 PF03193.11 KFM10888.1 - 0.00014 21.0 0.2 0.00035 19.8 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Ras PF00071.17 KFM10888.1 - 0.00044 19.6 0.0 0.00095 18.5 0.0 1.6 1 0 0 1 1 1 1 Ras family AAA_22 PF13401.1 KFM10888.1 - 0.0018 18.3 0.2 0.0094 16.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KFM10888.1 - 0.0051 16.2 0.0 0.0087 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain Miro PF08477.8 KFM10888.1 - 0.0071 16.8 0.1 0.039 14.4 0.0 2.2 2 1 0 2 2 2 1 Miro-like protein ABC_tran PF00005.22 KFM10888.1 - 0.0074 16.5 0.1 0.018 15.3 0.1 1.7 1 1 0 1 1 1 1 ABC transporter Gtr1_RagA PF04670.7 KFM10888.1 - 0.0095 15.0 0.2 0.14 11.2 0.0 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 KFM10888.1 - 0.017 14.6 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 KFM10888.1 - 0.023 14.7 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.9 KFM10888.1 - 0.064 12.9 0.1 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B IIGP PF05049.8 KFM10888.1 - 0.085 11.6 0.4 0.39 9.4 0.0 2.1 3 0 0 3 3 3 0 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.13 KFM10888.1 - 0.14 11.6 0.0 0.35 10.2 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family RhoGEF PF00621.15 KFM10889.1 - 1.4e-35 122.7 4.3 2.9e-35 121.7 3.0 1.6 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 KFM10889.1 - 6e-26 90.6 0.5 3.2e-14 52.9 0.2 2.7 2 0 0 2 2 2 2 PH domain FERM_C PF09380.5 KFM10889.1 - 9.5e-26 89.8 0.2 2e-25 88.7 0.1 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.5 KFM10889.1 - 1.8e-16 59.9 0.1 6.4e-16 58.1 0.1 2.0 1 0 0 1 1 1 1 FERM N-terminal domain FERM_M PF00373.13 KFM10889.1 - 3.5e-15 56.3 0.3 9.9e-15 54.8 0.2 1.8 1 0 0 1 1 1 1 FERM central domain FA PF08736.6 KFM10889.1 - 3.6e-13 49.0 0.5 9.8e-13 47.6 0.3 1.7 1 0 0 1 1 1 1 FERM adjacent (FA) PH_7 PF15408.1 KFM10889.1 - 0.0089 15.8 0.1 0.1 12.4 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.1 KFM10889.1 - 1.2 9.3 11.9 9.5 6.5 1.1 4.6 4 2 0 4 4 4 0 Pleckstrin homology domain Pkinase PF00069.20 KFM10890.1 - 1.3e-71 240.8 0.0 1.6e-71 240.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM10890.1 - 8.8e-53 179.0 0.0 1.4e-52 178.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM10890.1 - 0.00032 19.7 0.0 0.00094 18.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like DUF1241 PF06840.6 KFM10890.1 - 0.0011 18.2 0.0 0.0024 17.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) APH PF01636.18 KFM10890.1 - 0.031 13.9 0.0 0.59 9.8 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF4288 PF14119.1 KFM10890.1 - 0.094 12.8 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) Bcl-2 PF00452.14 KFM10891.1 - 5.7e-29 100.2 0.1 1.3e-28 99.0 0.0 1.6 2 0 0 2 2 2 1 Apoptosis regulator proteins, Bcl-2 family DAGK_acc PF00609.14 KFM10892.1 - 5.3e-58 195.6 0.0 3.8e-56 189.6 0.0 2.3 2 0 0 2 2 2 1 Diacylglycerol kinase accessory domain DAG_kinase_N PF14513.1 KFM10892.1 - 1.9e-51 173.8 0.0 4.1e-51 172.7 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase N-terminus DAGK_cat PF00781.19 KFM10892.1 - 7.8e-31 106.2 0.0 1.4e-30 105.4 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.17 KFM10892.1 - 6.6e-22 76.9 29.8 6e-11 41.8 6.5 2.7 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) EF-hand_1 PF00036.27 KFM10892.1 - 6.1e-11 40.7 1.9 0.00022 20.2 0.2 3.0 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 KFM10892.1 - 5.8e-10 39.1 0.4 1.5e-09 37.8 0.3 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KFM10892.1 - 3.9e-08 32.5 0.3 0.00082 19.0 0.1 3.4 1 1 1 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 KFM10892.1 - 1.9e-07 30.0 1.2 0.0058 15.9 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 KFM10892.1 - 6.2e-07 28.9 0.3 0.16 11.6 0.1 3.6 3 0 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFM10892.1 - 0.00022 21.2 0.2 0.00085 19.3 0.1 2.0 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region C1_3 PF07649.7 KFM10892.1 - 9.2 6.4 20.8 8.5 6.5 4.9 2.9 2 0 0 2 2 2 0 C1-like domain IncA PF04156.9 KFM10893.1 - 3.3e-05 23.5 0.0 4.5e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 IncA protein PSI PF01437.20 KFM10893.1 - 0.00011 22.2 10.9 0.00023 21.2 7.6 1.6 1 0 0 1 1 1 1 Plexin repeat Shisa PF13908.1 KFM10893.1 - 0.00011 22.4 0.5 0.00011 22.3 0.3 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Corona_S2 PF01601.11 KFM10893.1 - 0.00081 17.6 0.4 0.0011 17.1 0.3 1.2 1 0 0 1 1 1 1 Coronavirus S2 glycoprotein DUF1191 PF06697.7 KFM10893.1 - 0.0025 16.6 0.1 0.0027 16.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Orthoreo_P10 PF07204.6 KFM10893.1 - 0.004 16.8 0.1 0.006 16.2 0.0 1.3 1 0 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 EphA2_TM PF14575.1 KFM10893.1 - 0.0069 16.7 0.2 0.011 16.1 0.1 1.4 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.1 KFM10893.1 - 0.012 15.3 0.1 0.015 15.0 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Rhabdo_glycop PF00974.13 KFM10893.1 - 0.015 13.5 0.1 0.017 13.3 0.1 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein CD34_antigen PF06365.7 KFM10893.1 - 0.098 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family FAM176 PF14851.1 KFM10893.1 - 0.12 12.0 0.6 0.16 11.6 0.4 1.1 1 0 0 1 1 1 0 FAM176 family TMEM154 PF15102.1 KFM10893.1 - 0.13 11.9 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family CCER1 PF15482.1 KFM10893.1 - 0.21 11.2 6.6 0.11 12.0 3.6 1.3 1 1 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 Prominin PF05478.6 KFM10893.1 - 0.96 6.9 3.6 1.2 6.6 2.5 1.1 1 0 0 1 1 1 0 Prominin UQ_con PF00179.21 KFM10894.1 - 3.2e-47 159.4 0.0 3.5e-47 159.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme EPTP PF03736.12 KFM10895.1 - 3.1e-59 196.4 14.7 7.6e-14 51.1 0.3 8.0 7 1 0 7 7 7 7 EPTP domain Laminin_G_3 PF13385.1 KFM10895.1 - 4.9e-07 30.1 0.0 1.9e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.19 KFM10895.1 - 2.1e-06 27.7 0.0 4.1e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.18 KFM10895.1 - 0.013 15.4 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 Laminin G domain LRR_8 PF13855.1 KFM10896.1 - 3.4e-16 58.7 1.3 1.3e-10 40.8 0.0 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 KFM10896.1 - 6e-11 40.7 0.6 0.0085 15.9 0.0 4.6 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_4 PF12799.2 KFM10896.1 - 4.4e-10 38.9 0.7 6.8e-05 22.3 0.0 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRRNT PF01462.13 KFM10896.1 - 3e-08 32.9 3.0 1.3e-07 30.9 2.0 2.2 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_7 PF13504.1 KFM10896.1 - 3.3e-07 29.4 1.8 0.22 11.8 0.0 5.1 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 KFM10896.1 - 6.1e-06 25.7 0.1 0.16 12.1 0.0 3.9 4 0 0 4 4 4 2 Leucine Rich repeat LRR_5 PF13306.1 KFM10896.1 - 5.6e-05 22.8 0.0 8.7e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LSR PF05624.9 KFM10896.1 - 1 9.1 9.9 0.86 9.3 4.0 2.4 2 0 0 2 2 2 0 Lipolysis stimulated receptor (LSR) F5_F8_type_C PF00754.20 KFM10897.1 - 7.4e-12 45.2 0.0 8.5e-12 45.0 0.0 1.0 1 0 0 1 1 1 1 F5/8 type C domain Nramp PF01566.13 KFM10898.1 - 5.3e-116 387.3 12.6 5.3e-116 387.3 8.8 1.4 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein LETM1 PF07766.8 KFM10899.1 - 3.7e-46 157.3 0.4 4.4e-46 157.0 0.3 1.0 1 0 0 1 1 1 1 LETM1-like protein 7tm_1 PF00001.16 KFM10900.1 - 8.6e-40 136.4 22.6 9.9e-40 136.2 15.7 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3611 PF12263.3 KFM10900.1 - 0.0063 15.9 0.5 0.0063 15.9 0.3 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF3611) DUF2852 PF11014.3 KFM10900.1 - 0.13 12.2 1.3 0.67 9.9 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) DUF2976 PF11190.3 KFM10900.1 - 0.56 9.7 8.4 0.13 11.8 2.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) NfeD PF01957.13 KFM10900.1 - 3.8 7.6 6.7 1.5 8.9 0.1 2.5 2 1 0 2 2 2 0 NfeD-like C-terminal, partner-binding zf-LITAF-like PF10601.4 KFM10900.1 - 5.4 6.9 9.3 0.73 9.7 0.5 3.1 1 1 0 2 2 2 0 LITAF-like zinc ribbon domain 7tm_1 PF00001.16 KFM10901.1 - 3e-36 124.8 18.7 3.5e-36 124.6 13.0 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 KFM10901.1 - 3.3e-05 23.1 15.4 5e-05 22.5 10.7 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv DUF2852 PF11014.3 KFM10901.1 - 0.1 12.5 2.3 0.3 11.0 0.3 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2852) NfeD PF01957.13 KFM10901.1 - 4 7.5 5.8 0.66 10.1 0.4 2.5 1 1 2 3 3 3 0 NfeD-like C-terminal, partner-binding 7tm_1 PF00001.16 KFM10902.1 - 1.3e-43 149.0 21.7 1.5e-43 148.8 15.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 KFM10902.1 - 0.0039 16.3 33.4 0.092 11.8 23.1 2.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF360 PF04020.8 KFM10902.1 - 7.6 6.9 12.4 13 6.2 1.5 3.4 1 1 1 2 2 2 0 Membrane protein of unknown function 7tm_1 PF00001.16 KFM10903.1 - 4.3e-36 124.3 20.6 5.1e-36 124.1 14.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Ni_hydr_CYTB PF01292.15 KFM10903.1 - 0.058 12.7 4.7 0.052 12.9 1.0 2.5 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 YtpI PF14007.1 KFM10903.1 - 0.067 13.1 13.3 0.62 10.0 0.0 3.9 1 1 2 3 3 3 0 YtpI-like protein PgaD PF13994.1 KFM10903.1 - 0.52 9.7 6.1 1.1 8.7 0.4 2.7 2 1 1 3 3 3 0 PgaD-like protein UPF0104 PF03706.8 KFM10904.1 - 0.00028 20.2 5.6 0.00028 20.2 3.9 1.6 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0104) Claudin_2 PF13903.1 KFM10904.1 - 0.0014 18.3 9.6 0.0014 18.3 6.7 1.7 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Synaptobrevin PF00957.16 KFM10904.1 - 0.06 12.9 2.5 0.11 12.1 0.0 2.3 2 0 0 2 2 2 0 Synaptobrevin DUF3671 PF12420.3 KFM10904.1 - 3.5 7.6 8.2 37 4.3 5.7 2.4 1 1 0 1 1 1 0 Protein of unknown function DUF4205 PF13898.1 KFM10905.1 - 7.4e-34 116.9 0.0 8.1e-34 116.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) Gag_p30 PF02093.11 KFM10906.1 - 2.1e-20 72.8 0.2 2.5e-20 72.6 0.1 1.0 1 0 0 1 1 1 1 Gag P30 core shell protein Gag_p24 PF00607.15 KFM10906.1 - 0.00014 21.5 0.4 0.00036 20.1 0.2 1.6 1 1 0 1 1 1 1 gag gene protein p24 (core nucleocapsid protein) DUF3596 PF12167.3 KFM10906.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3596) Sina PF03145.11 KFM10907.1 - 3.7e-66 222.5 0.5 4.1e-66 222.4 0.3 1.0 1 0 0 1 1 1 1 Seven in absentia protein family FAM194 PF14977.1 KFM10908.1 - 2.4e-60 203.0 0.0 2.8e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 FAM194 protein 7tm_1 PF00001.16 KFM10909.1 - 1e-30 106.7 8.3 1.2e-30 106.5 5.8 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 KFM10909.1 - 3.6e-05 23.0 1.7 0.00097 18.3 0.7 2.3 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.4 KFM10909.1 - 4.2e-05 22.8 1.0 6.5e-05 22.1 0.7 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srbc PF10316.4 KFM10909.1 - 0.011 14.9 0.2 0.019 14.2 0.2 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srbc YrhC PF14143.1 KFM10909.1 - 0.058 13.3 3.2 0.16 11.9 2.2 1.7 1 0 0 1 1 1 0 YrhC-like protein 7TM_GPCR_Srsx PF10320.4 KFM10909.1 - 0.46 9.6 8.0 0.87 8.6 5.6 1.5 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Tad PF13400.1 KFM10909.1 - 0.7 9.9 0.1 0.7 9.9 0.0 2.6 3 0 0 3 3 3 0 Putative Flp pilus-assembly TadE/G-like Rdx PF10262.4 KFM10910.1 - 1.4e-14 53.8 0.0 1.7e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Rdx family eIF2A PF08662.6 KFM10911.1 - 1.4e-79 266.3 2.2 2.7e-77 258.8 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 KFM10911.1 - 0.11 12.4 2.1 45 4.1 0.0 4.8 5 0 0 5 5 5 0 WD domain, G-beta repeat CRT10 PF08728.5 KFM10911.1 - 1 7.2 3.7 1.5 6.7 2.6 1.2 1 0 0 1 1 1 0 CRT10 TSC22 PF01166.13 KFM10912.1 - 1.8e-28 98.2 5.6 2.2e-28 98.0 3.9 1.1 1 0 0 1 1 1 1 TSC-22/dip/bun family DUF972 PF06156.8 KFM10912.1 - 0.0028 17.9 3.0 0.0033 17.7 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF972) DivIC PF04977.10 KFM10912.1 - 0.0039 16.6 3.1 0.0044 16.4 1.9 1.3 1 1 0 1 1 1 1 Septum formation initiator MAD PF05557.8 KFM10912.1 - 0.0046 15.1 2.5 0.0051 14.9 1.8 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein DUF16 PF01519.11 KFM10912.1 - 0.029 14.5 1.0 0.03 14.5 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF16 XhlA PF10779.4 KFM10912.1 - 0.034 14.0 1.8 0.034 14.0 1.2 1.4 2 0 0 2 2 2 0 Haemolysin XhlA CtsR PF05848.6 KFM10912.1 - 0.039 13.9 0.7 0.042 13.8 0.5 1.1 1 0 0 1 1 1 0 Firmicute transcriptional repressor of class III stress genes (CtsR) DUF904 PF06005.7 KFM10912.1 - 0.043 14.1 8.9 0.21 11.9 6.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Sipho_Gp157 PF05565.6 KFM10912.1 - 0.046 13.3 0.8 0.053 13.1 0.5 1.1 1 0 0 1 1 1 0 Siphovirus Gp157 Cep57_CLD_2 PF14197.1 KFM10912.1 - 0.052 13.4 4.8 0.071 13.0 3.3 1.2 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Fzo_mitofusin PF04799.8 KFM10912.1 - 0.13 11.6 1.5 0.14 11.4 1.1 1.0 1 0 0 1 1 1 0 fzo-like conserved region Shugoshin_N PF07558.6 KFM10912.1 - 0.29 10.8 4.7 0.49 10.1 3.2 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region bZIP_2 PF07716.10 KFM10912.1 - 0.76 9.6 6.0 1.4 8.7 4.1 1.5 1 1 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.16 KFM10912.1 - 0.8 9.7 5.0 1 9.3 3.2 1.5 1 1 0 1 1 1 0 bZIP transcription factor Profilin PF00235.14 KFM10913.1 - 6.8e-12 45.5 0.0 7.5e-12 45.4 0.0 1.0 1 0 0 1 1 1 1 Profilin zf-RING_2 PF13639.1 KFM10914.1 - 1.7e-15 56.5 7.7 2.8e-15 55.8 5.4 1.4 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 KFM10914.1 - 2.8e-13 49.4 0.0 6.1e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.2 KFM10914.1 - 8.7e-09 35.3 3.4 1.7e-08 34.4 2.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KFM10914.1 - 1.5e-08 34.1 8.4 2.5e-08 33.4 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM10914.1 - 6.5e-07 29.2 8.6 1.1e-06 28.5 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM10914.1 - 9e-07 28.5 7.1 1.4e-06 27.8 4.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFM10914.1 - 1e-06 28.2 5.7 1.7e-06 27.6 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFM10914.1 - 0.0011 18.7 5.5 0.0026 17.5 3.8 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Neur_chan_memb PF02932.11 KFM10914.1 - 0.0053 16.6 0.0 0.0099 15.7 0.0 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Baculo_11_kDa PF06143.6 KFM10914.1 - 0.054 12.8 0.6 1.7 8.0 0.1 3.0 3 0 0 3 3 3 0 Baculovirus 11 kDa family PHD PF00628.24 KFM10914.1 - 0.1 12.2 8.6 0.18 11.5 5.9 1.4 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.2 KFM10914.1 - 0.18 11.8 7.7 0.39 10.7 5.4 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.1 KFM10914.1 - 0.48 10.0 8.6 1 8.9 6.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF2976 PF11190.3 KFM10914.1 - 0.8 9.2 3.3 2 8.0 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) FANCL_C PF11793.3 KFM10914.1 - 5.7 6.9 8.9 46 4.0 6.2 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain HCaRG PF07258.9 KFM10916.1 - 1.9e-27 95.9 3.3 2.1e-27 95.8 2.3 1.0 1 0 0 1 1 1 1 HCaRG protein HTH_1 PF00126.22 KFM10916.1 - 0.01 15.5 0.4 0.073 12.8 0.1 2.1 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family SOCS PF12610.3 KFM10916.1 - 0.041 14.2 0.4 0.11 12.8 0.1 1.8 2 0 0 2 2 2 0 Suppressor of cytokine signalling FAM131 PF15010.1 KFM10917.1 - 0.21 11.2 1.1 0.3 10.7 0.7 1.2 1 0 0 1 1 1 0 Putative cell signalling L6_membrane PF05805.7 KFM10918.1 - 1.4e-73 246.6 19.5 1.9e-73 246.1 13.5 1.2 1 0 0 1 1 1 1 L6 membrane protein Yip1 PF04893.12 KFM10918.1 - 5.7 6.4 8.3 21 4.5 5.6 2.1 1 1 0 1 1 1 0 Yip1 domain L6_membrane PF05805.7 KFM10919.1 - 4.4e-76 254.8 15.0 5e-76 254.6 10.4 1.0 1 0 0 1 1 1 1 L6 membrane protein Yip1 PF04893.12 KFM10919.1 - 0.0018 17.8 1.2 0.0018 17.8 0.8 2.1 2 0 0 2 2 2 1 Yip1 domain Cation_efflux PF01545.16 KFM10919.1 - 0.47 9.4 4.7 0.047 12.7 0.3 1.4 2 0 0 2 2 2 0 Cation efflux family L6_membrane PF05805.7 KFM10920.1 - 8.7e-60 201.6 15.4 9.7e-60 201.4 10.7 1.0 1 0 0 1 1 1 1 L6 membrane protein DUF3753 PF12575.3 KFM10920.1 - 1.1 9.1 0.0 1.1 9.1 0.0 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF3753) Cu-oxidase_3 PF07732.10 KFM10921.1 - 1e-29 102.6 4.1 2.3e-09 37.0 0.0 5.3 4 0 0 4 4 4 4 Multicopper oxidase Cu-oxidase_2 PF07731.9 KFM10921.1 - 7.7e-27 93.4 13.8 1.1e-14 54.0 3.5 6.3 6 0 0 6 6 6 4 Multicopper oxidase HPS3_C PF14763.1 KFM10922.1 - 3.4e-182 605.1 3.5 5.5e-182 604.5 2.4 1.3 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 3, C-terminal HPS3_Mid PF14762.1 KFM10922.1 - 1.1e-153 511.3 5.3 1.8e-153 510.6 3.4 1.5 2 0 0 2 2 2 1 Hermansky-Pudlak syndrome 3, middle region HPS3_N PF14761.1 KFM10922.1 - 2e-15 56.7 0.4 4.1e-15 55.7 0.3 1.5 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 3 Tubulin PF00091.20 KFM10923.1 - 6.2e-69 232.1 0.0 7.9e-69 231.7 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFM10923.1 - 4.5e-51 172.1 0.0 6.9e-51 171.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KFM10923.1 - 0.0012 18.3 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain SNF2_N PF00176.18 KFM10924.1 - 1.9e-83 279.7 0.1 2.9e-83 279.1 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 KFM10924.1 - 7.7e-18 64.3 0.0 1.5e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 KFM10924.1 - 1.5e-11 43.9 0.0 4.2e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 KFM10924.1 - 1.6e-09 37.4 8.7 4e-09 36.1 6.1 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KFM10924.1 - 2.5e-08 33.4 9.0 6e-08 32.2 6.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM10924.1 - 5e-08 32.8 9.9 5e-08 32.8 6.9 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM10924.1 - 9.9e-08 31.5 7.2 2.5e-07 30.2 5.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM10924.1 - 1.2e-06 28.1 7.8 3.4e-06 26.6 5.4 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFM10924.1 - 1.3e-05 24.9 10.1 3.6e-05 23.5 7.0 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 KFM10924.1 - 0.00011 21.9 0.9 0.00027 20.6 0.6 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 KFM10924.1 - 0.00014 21.8 2.3 0.00042 20.3 1.6 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KFM10924.1 - 0.0019 17.8 6.5 0.005 16.5 4.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 KFM10924.1 - 0.0052 16.2 4.7 0.019 14.4 3.3 2.0 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit HDA2-3 PF11496.3 KFM10924.1 - 0.046 12.5 0.5 2.3 6.9 0.0 3.0 2 1 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 zf-RING_6 PF14835.1 KFM10924.1 - 0.11 12.2 5.8 0.27 11.0 4.0 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 KFM10924.1 - 0.59 9.7 5.6 1.3 8.6 3.9 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Glyco_transf_8 PF01501.15 KFM10925.1 - 1.5e-37 129.3 0.0 2.5e-37 128.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 C1q PF00386.16 KFM10926.1 - 6.6e-41 139.2 0.6 8.2e-41 138.9 0.4 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 KFM10926.1 - 2.8e-10 39.6 30.5 5.5e-09 35.4 21.2 2.2 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) PPV_E2_N PF00508.12 KFM10926.1 - 0.031 13.4 0.6 0.041 13.0 0.2 1.3 1 1 0 1 1 1 0 E2 (early) protein, N terminal OTOS PF15182.1 KFM10927.1 - 3.5e-25 87.4 3.1 3.7e-25 87.3 2.2 1.0 1 0 0 1 1 1 1 Otospiralin Glypican PF01153.14 KFM10928.1 - 1.9e-115 386.5 4.3 2.2e-115 386.4 3.0 1.0 1 0 0 1 1 1 1 Glypican Spore_III_AB PF09548.5 KFM10928.1 - 0.21 11.3 1.7 0.73 9.5 0.2 2.4 2 1 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Ins_beta PF03488.9 KFM10928.1 - 0.6 9.9 4.5 2.3 8.0 0.0 3.4 4 0 0 4 4 4 0 Nematode insulin-related peptide beta type Glypican PF01153.14 KFM10929.1 - 1.9e-210 700.1 2.0 2.2e-210 700.0 1.4 1.0 1 0 0 1 1 1 1 Glypican DUF4496 PF14908.1 KFM10930.1 - 0.049 13.5 0.0 0.066 13.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4496) DSPc PF00782.15 KFM10931.1 - 2.4e-31 108.0 0.0 2.7e-31 107.8 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Toxin_17 PF08086.6 KFM10931.1 - 0.047 13.7 0.3 0.092 12.8 0.2 1.5 1 0 0 1 1 1 0 Ergtoxin family Y_phosphatase PF00102.22 KFM10931.1 - 0.061 12.6 0.0 0.07 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPn PF14671.1 KFM10931.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half PMP22_Claudin PF00822.15 KFM10932.1 - 1.9e-34 118.7 12.9 2.4e-34 118.3 8.9 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFM10932.1 - 1.8e-09 37.4 12.0 2.2e-09 37.2 7.7 1.6 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.7 KFM10932.1 - 0.00032 20.0 8.7 0.029 13.6 0.9 2.1 1 1 0 2 2 2 2 Clc-like Amastin PF07344.6 KFM10932.1 - 2.3 7.8 14.3 0.14 11.7 4.6 2.2 1 1 1 2 2 2 0 Amastin surface glycoprotein Rhomboid PF01694.17 KFM10933.1 - 2.7e-24 85.8 17.2 2.2e-23 82.9 9.8 2.2 2 1 0 2 2 2 2 Rhomboid family YEATS PF03366.11 KFM10934.1 - 6.6e-25 86.6 3.6 7.2e-25 86.5 0.6 2.2 2 0 0 2 2 2 1 YEATS family Kelch_1 PF01344.20 KFM10935.1 - 5.4e-53 176.3 20.7 1.1e-13 50.4 0.0 7.0 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.1 KFM10935.1 - 3.1e-37 125.2 9.2 6.1e-07 29.3 0.0 6.6 3 1 3 6 6 6 6 Kelch motif BACK PF07707.10 KFM10935.1 - 2.3e-32 110.8 0.6 2.3e-32 110.8 0.4 1.6 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.26 KFM10935.1 - 7.4e-29 99.9 1.7 1.5e-28 98.9 0.6 2.0 2 0 0 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.1 KFM10935.1 - 2.6e-28 97.5 5.2 5.9e-05 23.1 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.1 KFM10935.1 - 8.4e-25 86.2 6.7 3.1e-05 23.6 0.0 7.0 6 2 1 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.10 KFM10935.1 - 3.1e-21 74.2 11.7 1.1e-05 24.9 0.1 6.6 6 1 0 6 6 6 5 Kelch motif Kelch_5 PF13854.1 KFM10935.1 - 9.8e-10 38.1 9.7 0.092 12.7 0.1 6.0 6 0 0 6 6 6 3 Kelch motif DUF3342 PF11822.3 KFM10935.1 - 0.0024 17.0 0.8 0.0045 16.1 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) Kelch_1 PF01344.20 KFM10936.1 - 4.9e-44 147.6 0.2 1.7e-12 46.7 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 KFM10936.1 - 2.9e-34 115.8 0.1 1.4e-06 28.1 0.0 5.9 2 1 4 6 6 6 5 Kelch motif BACK PF07707.10 KFM10936.1 - 8e-32 109.1 0.3 1.8e-31 108.0 0.2 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.26 KFM10936.1 - 4.4e-28 97.4 5.1 2.4e-27 95.1 1.6 2.4 1 1 1 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.10 KFM10936.1 - 6.5e-27 92.2 0.7 1.3e-05 24.7 0.0 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_4 PF13418.1 KFM10936.1 - 3.7e-16 58.6 0.0 0.029 14.1 0.0 6.2 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.1 KFM10936.1 - 7.9e-16 57.7 0.1 0.013 15.6 0.0 5.8 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 KFM10936.1 - 9.5e-13 47.7 1.2 0.00041 20.2 0.0 6.0 6 0 0 6 6 6 2 Kelch motif DUF3342 PF11822.3 KFM10936.1 - 0.00028 20.1 3.1 0.00036 19.7 0.5 2.1 1 1 0 2 2 2 1 Domain of unknown function (DUF3342) 7tm_1 PF00001.16 KFM10937.1 - 3.1e-09 36.3 27.8 6.1e-09 35.3 19.1 1.6 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) MRAP PF15183.1 KFM10937.1 - 0.15 11.6 0.2 0.15 11.6 0.1 3.9 3 1 2 5 5 5 0 Melanocortin-2 receptor accessory protein family RhoGEF PF00621.15 KFM10938.1 - 9.4e-50 168.9 6.8 9.4e-50 168.9 4.7 1.5 2 0 0 2 2 2 1 RhoGEF domain SH3_9 PF14604.1 KFM10938.1 - 1.8e-12 46.6 0.2 3.3e-12 45.7 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 KFM10938.1 - 3.3e-10 40.1 0.5 6.5e-10 39.1 0.4 1.5 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.23 KFM10938.1 - 4e-10 38.9 1.9 7.3e-10 38.0 1.3 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFM10938.1 - 7.8e-08 31.6 0.0 1.5e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_5 PF15405.1 KFM10938.1 - 0.047 13.6 0.2 0.34 10.8 0.0 2.2 1 1 1 2 2 2 0 Pleckstrin homology domain TCRP1 PF14944.1 KFM10940.1 - 1.1e-108 361.5 53.2 1.2e-108 361.4 36.9 1.0 1 0 0 1 1 1 1 Tongue Cancer Chemotherapy Resistant Protein 1 PH PF00169.24 KFM10941.1 - 1.5e-09 37.9 0.1 2.1e-09 37.4 0.1 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KFM10941.1 - 0.18 12.0 0.4 0.28 11.4 0.3 1.4 1 1 0 1 1 1 0 Pleckstrin homology domain Sulfotransfer_2 PF03567.9 KFM10942.1 - 3.4e-17 62.9 0.1 3.6e-17 62.9 0.1 1.0 1 0 0 1 1 1 1 Sulfotransferase family PPV_E2_C PF00511.12 KFM10942.1 - 0.038 13.9 1.9 0.045 13.6 1.3 1.2 1 0 0 1 1 1 0 E2 (early) protein, C terminal Sulfotransfer_2 PF03567.9 KFM10943.1 - 1.7e-48 165.5 0.5 2.5e-48 164.9 0.3 1.3 1 0 0 1 1 1 1 Sulfotransferase family Spore_III_AB PF09548.5 KFM10943.1 - 0.028 14.1 0.1 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) UDP-g_GGTase PF06427.6 KFM10944.1 - 2.8e-78 262.0 0.1 1.6e-76 256.3 0.0 3.1 3 0 0 3 3 3 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 KFM10944.1 - 1.2e-06 28.1 0.6 1.2e-06 28.1 0.4 2.2 3 0 0 3 3 3 1 Glycosyl transferase family 8 AMMECR1 PF01871.12 KFM10946.1 - 4.6e-45 152.8 0.0 6.3e-45 152.3 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 RNA_pol_Rpb4 PF03874.11 KFM10947.1 - 6.7e-29 100.2 5.4 7.5e-29 100.1 3.8 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb4 Rop PF01815.11 KFM10947.1 - 0.00037 19.9 0.8 0.00094 18.5 0.6 1.6 1 0 0 1 1 1 1 Rop protein Birna_VP5 PF03042.9 KFM10947.1 - 0.05 13.1 0.0 0.07 12.6 0.0 1.2 1 0 0 1 1 1 0 Birnavirus VP5 protein Maelstrom PF13017.1 KFM10947.1 - 0.059 12.8 0.3 0.069 12.6 0.2 1.0 1 0 0 1 1 1 0 piRNA pathway germ-plasm component WD40 PF00400.27 KFM10948.1 - 1.7e-49 163.9 10.6 5.2e-09 35.6 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KFM10948.1 - 1.6e-05 24.6 3.0 0.088 12.5 0.5 2.8 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Collagen PF01391.13 KFM10948.1 - 3.5e-05 23.2 51.3 0.00026 20.4 17.5 9.8 6 1 2 8 8 8 2 Collagen triple helix repeat (20 copies) LIM PF00412.17 KFM10949.1 - 3.1e-61 203.3 60.3 2.5e-14 53.0 2.3 5.1 5 0 0 5 5 5 5 LIM domain 7tm_1 PF00001.16 KFM10950.1 - 9.4e-54 182.2 18.0 1.3e-53 181.8 12.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM10950.1 - 1.1e-06 28.0 18.7 1.3e-06 27.7 13.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 KFM10950.1 - 0.00014 21.0 15.8 0.00014 21.0 10.9 1.6 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv Srg PF02118.16 KFM10950.1 - 0.3 10.5 23.1 0.084 12.3 13.6 1.8 1 1 1 2 2 2 0 Srg family chemoreceptor 60KD_IMP PF02096.15 KFM10950.1 - 1.5 8.4 5.8 2.2 7.8 3.2 2.1 2 1 0 2 2 2 0 60Kd inner membrane protein SdpI PF13630.1 KFM10950.1 - 8.2 6.2 10.8 1.5e+03 -1.1 0.0 3.6 2 1 0 2 2 2 0 SdpI/YhfL protein family Med26 PF08711.6 KFM10951.1 - 1.2e-17 63.1 0.0 5.3e-17 61.0 0.0 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Trypsin PF00089.21 KFM10952.1 - 4.2e-59 199.8 0.0 4.5e-59 199.6 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 KFM10952.1 - 0.00051 20.0 0.0 0.00074 19.5 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.6 KFM10952.1 - 0.0031 16.8 0.1 0.011 15.0 0.0 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF1986) DAGK_acc PF00609.14 KFM10953.1 - 1e-52 178.5 0.0 2.2e-52 177.4 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 KFM10953.1 - 1.1e-29 102.4 0.0 2.4e-29 101.3 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.17 KFM10953.1 - 3.7e-20 71.4 25.0 1.5e-11 43.8 3.8 2.8 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) SAM_2 PF07647.12 KFM10953.1 - 2.8e-19 68.7 0.9 1.2e-18 66.6 0.1 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFM10953.1 - 1.6e-17 63.4 2.3 1.2e-16 60.6 0.3 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH PF00169.24 KFM10953.1 - 2.5e-16 59.7 0.3 6.8e-16 58.3 0.2 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KFM10953.1 - 1.6e-07 31.5 5.5 7.2e-07 29.4 1.3 3.2 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 KFM10953.1 - 8.2e-05 22.5 0.2 0.00019 21.4 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain C1_3 PF07649.7 KFM10953.1 - 0.0063 16.5 2.8 0.0063 16.5 2.0 3.1 2 1 0 2 2 2 1 C1-like domain Mcp5_PH PF12814.2 KFM10953.1 - 0.0083 16.0 0.1 0.023 14.5 0.1 1.8 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Arrestin_N PF00339.24 KFM10955.1 - 4.5e-37 127.1 0.1 1.5e-32 112.4 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KFM10955.1 - 2.3e-19 69.8 3.3 3.4e-19 69.3 2.3 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Transglut_C PF00927.17 KFM10955.1 - 0.0041 17.1 0.8 0.0088 16.0 0.4 1.7 2 0 0 2 2 2 1 Transglutaminase family, C-terminal ig like domain DUF974 PF06159.8 KFM10955.1 - 0.017 14.5 0.1 0.027 13.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF974) DUF2393 PF09624.5 KFM10955.1 - 0.029 13.9 0.3 0.058 12.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) DUF2079 PF09852.4 KFM10955.1 - 0.041 12.6 0.1 0.054 12.2 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) LDB19 PF13002.2 KFM10955.1 - 0.071 12.6 0.0 3 7.3 0.0 2.2 2 0 0 2 2 2 0 Arrestin_N terminal like DUF3343 PF11823.3 KFM10955.1 - 0.075 12.3 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) ATG16 PF08614.6 KFM10956.1 - 3.3e-52 177.1 27.7 3.3e-52 177.1 19.2 1.8 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) WD40 PF00400.27 KFM10956.1 - 5.8e-42 140.1 15.4 1.6e-09 37.2 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KFM10956.1 - 3.7e-07 30.0 0.0 0.062 13.0 0.0 3.4 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KFM10956.1 - 0.00015 20.0 8.0 0.89 7.6 0.0 4.6 2 1 3 5 5 5 3 Nucleoporin Nup120/160 ERM PF00769.14 KFM10956.1 - 0.0067 15.9 28.4 0.0067 15.9 19.7 1.6 1 1 0 1 1 1 1 Ezrin/radixin/moesin family DUF4200 PF13863.1 KFM10956.1 - 0.01 15.7 22.8 0.01 15.7 15.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF904 PF06005.7 KFM10956.1 - 0.019 15.2 8.7 0.019 15.2 6.0 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF904) HTH_6 PF01418.12 KFM10956.1 - 0.066 12.9 0.9 0.19 11.4 0.6 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family CALCOCO1 PF07888.6 KFM10956.1 - 0.082 11.1 17.5 0.15 10.2 12.1 1.4 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like V_ATPase_I PF01496.14 KFM10956.1 - 0.11 10.2 14.3 0.16 9.8 9.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Reo_sigmaC PF04582.7 KFM10956.1 - 0.29 10.2 2.3 0.52 9.4 1.6 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Hira PF07569.6 KFM10956.1 - 0.61 9.2 0.0 0.61 9.2 0.0 3.3 4 1 1 5 5 5 0 TUP1-like enhancer of split DUF641 PF04859.7 KFM10956.1 - 0.89 9.3 14.0 0.096 12.4 3.7 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF972 PF06156.8 KFM10956.1 - 0.96 9.8 22.0 0.15 12.3 5.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) NPV_P10 PF05531.7 KFM10956.1 - 1 9.6 4.9 0.63 10.3 0.5 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 KFM10956.1 - 1.4 8.7 7.1 4.2 7.1 4.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Synaptobrevin PF00957.16 KFM10956.1 - 1.4 8.5 6.5 2.1 8.0 3.4 2.1 2 0 0 2 2 2 0 Synaptobrevin TBPIP PF07106.8 KFM10956.1 - 2 7.9 25.6 0.018 14.5 10.0 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Allexi_40kDa PF05549.6 KFM10956.1 - 2.2 7.5 8.3 3.1 7.0 5.0 1.7 1 1 0 1 1 1 0 Allexivirus 40kDa protein IncA PF04156.9 KFM10956.1 - 2.7 7.5 35.5 0.16 11.5 13.4 2.3 1 1 1 2 2 2 0 IncA protein BLOC1_2 PF10046.4 KFM10956.1 - 2.9 8.1 16.8 0.21 11.7 3.0 2.8 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Syntaxin-6_N PF09177.6 KFM10956.1 - 8.3 6.8 17.9 0.23 11.9 3.1 3.1 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Exo_endo_phos PF03372.18 KFM10957.1 - 8.5e-25 88.1 0.0 2.2e-24 86.7 0.0 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SH2 PF00017.19 KFM10957.1 - 2.7e-17 62.3 0.0 8.7e-17 60.6 0.0 2.0 1 0 0 1 1 1 1 SH2 domain Imm11 PF15563.1 KFM10957.1 - 0.0006 18.9 0.4 0.0016 17.5 0.1 1.8 2 0 0 2 2 2 1 Immunity protein 11 BNR_2 PF13088.1 KFM10958.1 - 7.5e-31 107.4 0.0 9.9e-31 107.0 0.0 1.0 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.15 KFM10958.1 - 0.021 14.5 7.5 0.22 11.4 0.2 3.5 4 0 0 4 4 4 0 BNR/Asp-box repeat RhoGEF PF00621.15 KFM10960.1 - 2.3e-37 128.5 9.1 4.2e-37 127.7 6.3 1.4 1 0 0 1 1 1 1 RhoGEF domain SH3_1 PF00018.23 KFM10960.1 - 1.9e-12 46.3 0.0 5.7e-12 44.8 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KFM10960.1 - 2e-11 43.2 0.0 4.3e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFM10960.1 - 1.3e-07 31.0 0.0 2.8e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 KFM10960.1 - 0.00058 20.0 0.6 0.0021 18.2 0.0 2.2 2 1 0 2 2 2 1 PH domain GYF PF02213.11 KFM10962.1 - 7.5e-20 70.2 1.9 1.8e-19 69.0 1.3 1.7 1 0 0 1 1 1 1 GYF domain IRK PF01007.15 KFM10963.1 - 1.4e-90 303.4 0.0 1.7e-90 303.2 0.0 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 KFM10963.1 - 0.00027 20.5 3.6 0.00057 19.5 2.5 1.6 1 1 0 1 1 1 1 Ion channel EF-hand_7 PF13499.1 KFM10964.1 - 1.4e-09 37.9 0.5 1.4e-09 37.9 0.4 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KFM10964.1 - 1.9e-09 36.1 6.4 1.3e-05 24.0 0.5 2.7 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 KFM10964.1 - 7.4e-06 25.4 1.5 0.043 13.7 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 KFM10964.1 - 2.8e-05 23.6 3.0 5.9e-05 22.6 1.3 2.1 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 KFM10964.1 - 9.7e-05 21.5 1.9 0.048 13.0 0.3 2.6 2 0 0 2 2 2 2 EF hand VWD PF00094.20 KFM10965.1 - 5.1e-37 127.4 0.0 2.7e-23 82.8 0.0 2.4 2 0 0 2 2 2 2 von Willebrand factor type D domain C8 PF08742.6 KFM10965.1 - 6.1e-33 112.9 13.6 3.5e-18 65.6 1.6 4.1 4 0 0 4 4 4 2 C8 domain TIL PF01826.12 KFM10965.1 - 3e-23 81.6 40.5 4e-13 49.2 10.6 6.7 6 2 1 7 7 7 2 Trypsin Inhibitor like cysteine rich domain TILa PF12714.2 KFM10965.1 - 1.4e-11 43.9 9.8 1.4e-11 43.9 6.8 5.3 4 1 1 5 5 5 1 TILa domain cEGF PF12662.2 KFM10965.1 - 1.3 8.6 15.5 1 9.0 0.8 4.4 3 0 0 3 3 3 0 Complement Clr-like EGF-like VWD PF00094.20 KFM10966.1 - 8.1e-31 107.3 0.2 9e-31 107.1 0.1 1.0 1 0 0 1 1 1 1 von Willebrand factor type D domain DUF4097 PF13349.1 KFM10966.1 - 0.083 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) TILa PF12714.2 KFM10967.1 - 1e-25 89.2 112.8 0.029 14.1 1.6 12.0 12 0 0 12 12 12 12 TILa domain FOLN PF09289.5 KFM10967.1 - 1e-14 53.9 141.5 0.22 11.3 2.7 12.2 12 0 0 12 12 12 12 Follistatin/Osteonectin-like EGF domain CRF-BP PF05428.6 KFM10967.1 - 5.8e-06 25.3 39.8 7.1 5.3 0.1 11.6 8 3 4 12 12 12 11 Corticotropin-releasing factor binding protein (CRF-BP) CBM_1 PF00734.13 KFM10967.1 - 5.6 6.7 87.7 11 5.8 0.1 13.8 12 7 0 12 12 12 0 Fungal cellulose binding domain TILa PF12714.2 KFM10968.1 - 1.6e-19 69.4 107.8 0.024 14.3 1.2 11.1 7 3 4 11 11 11 11 TILa domain FOLN PF09289.5 KFM10968.1 - 4.8e-15 55.0 103.5 0.0068 16.2 2.3 11.9 11 2 0 11 11 11 10 Follistatin/Osteonectin-like EGF domain SH3_2 PF07653.12 KFM10968.1 - 1.2e-05 24.7 2.2 0.49 9.9 0.0 5.4 6 0 0 6 6 6 2 Variant SH3 domain CBM_1 PF00734.13 KFM10968.1 - 6e-05 22.6 69.2 0.083 12.5 0.6 11.8 11 0 0 11 11 11 10 Fungal cellulose binding domain Cypo_polyhedrin PF05865.6 KFM10968.1 - 0.15 11.2 0.0 16 4.5 0.0 2.1 2 0 0 2 2 2 0 Cypovirus polyhedrin protein FOLN PF09289.5 KFM10969.1 - 5.6e-15 54.8 81.5 0.0064 16.3 2.2 11.4 11 0 0 11 11 11 9 Follistatin/Osteonectin-like EGF domain TILa PF12714.2 KFM10969.1 - 6.9e-11 41.7 98.7 0.25 11.1 4.6 11.1 6 4 5 11 11 11 10 TILa domain SH3_2 PF07653.12 KFM10969.1 - 0.0089 15.5 0.1 26 4.3 0.0 4.8 5 1 0 5 5 5 1 Variant SH3 domain CBM_1 PF00734.13 KFM10969.1 - 1.4 8.6 64.1 0.15 11.7 0.6 11.4 11 1 0 11 11 11 0 Fungal cellulose binding domain CRF-BP PF05428.6 KFM10969.1 - 9.5 4.9 28.8 8.9 5.0 0.2 8.3 6 4 3 9 9 9 0 Corticotropin-releasing factor binding protein (CRF-BP) FOLN PF09289.5 KFM10970.1 - 2e-18 65.8 82.6 0.0031 17.3 1.4 12.1 10 3 2 12 12 12 11 Follistatin/Osteonectin-like EGF domain TILa PF12714.2 KFM10970.1 - 7.8e-15 54.3 103.6 0.068 12.9 2.3 11.0 7 3 4 11 11 11 11 TILa domain CBM_1 PF00734.13 KFM10970.1 - 7.4e-08 31.9 70.0 0.64 9.7 0.2 11.6 11 0 0 11 11 11 10 Fungal cellulose binding domain HALZ PF02183.13 KFM10972.1 - 0.072 12.8 0.1 0.072 12.8 0.1 24.7 25 3 2 27 27 27 0 Homeobox associated leucine zipper TPR_11 PF13414.1 KFM10973.1 - 3.2e-44 148.4 30.8 2.1e-15 56.1 2.2 6.7 3 3 3 7 7 7 7 TPR repeat TPR_1 PF00515.23 KFM10973.1 - 7.1e-39 129.8 17.9 3.7e-10 38.9 0.1 9.7 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 KFM10973.1 - 2.4e-38 126.9 12.5 1e-08 34.4 0.1 9.6 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_8 PF13181.1 KFM10973.1 - 1.1e-30 103.0 12.4 1.8e-05 24.1 0.0 9.2 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_17 PF13431.1 KFM10973.1 - 9.1e-30 100.3 24.5 3.9e-06 26.6 0.3 10.4 10 0 0 10 10 10 8 Tetratricopeptide repeat DUF1736 PF08409.6 KFM10973.1 - 5.4e-29 99.5 1.4 1.3e-28 98.3 1.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_16 PF13432.1 KFM10973.1 - 5.7e-26 90.5 5.7 4.8e-08 33.4 0.2 6.9 3 1 4 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.1 KFM10973.1 - 6.6e-25 86.8 15.1 9.3e-08 31.9 0.1 6.8 3 2 5 8 8 8 7 Tetratricopeptide repeat TPR_19 PF14559.1 KFM10973.1 - 3.7e-21 75.2 13.2 5.2e-08 33.1 0.8 6.5 2 1 6 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.1 KFM10973.1 - 5e-18 63.9 8.4 6.9e-05 23.1 0.0 8.8 3 2 6 9 9 9 4 Tetratricopeptide repeat TPR_6 PF13174.1 KFM10973.1 - 1.1e-10 41.1 12.9 0.032 14.6 0.1 8.6 9 0 0 9 9 9 2 Tetratricopeptide repeat Apc3 PF12895.2 KFM10973.1 - 1.4e-09 37.9 4.4 0.048 13.7 0.4 4.9 3 2 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KFM10973.1 - 5.8e-09 35.6 2.4 0.00084 19.1 0.1 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFM10973.1 - 3.6e-07 29.4 9.4 3 7.8 0.2 7.1 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_10 PF13374.1 KFM10973.1 - 4.3e-06 26.4 14.3 2.1 8.3 1.1 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat ChAPs PF09295.5 KFM10973.1 - 0.00014 20.7 8.1 0.018 13.8 0.3 2.9 1 1 2 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) PMT_2 PF13231.1 KFM10973.1 - 0.00073 19.4 8.3 0.00073 19.4 5.7 2.6 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase TPR_15 PF13429.1 KFM10973.1 - 0.0051 15.9 2.8 0.0051 15.9 1.9 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KFM10973.1 - 0.069 13.0 1.2 12 5.8 0.0 4.3 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat SCF PF02404.10 KFM10974.1 - 7.5e-156 517.2 2.2 8.4e-156 517.0 1.5 1.0 1 0 0 1 1 1 1 Stem cell factor DSPc PF00782.15 KFM10975.1 - 4.3e-43 146.0 0.0 5.9e-43 145.6 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.15 KFM10975.1 - 7.5e-06 26.2 0.0 3.2e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.22 KFM10975.1 - 7.2e-05 22.2 0.0 0.00011 21.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KFM10975.1 - 0.0066 16.5 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate WD40 PF00400.27 KFM10976.1 - 5.7e-70 228.8 17.9 4.4e-13 48.5 0.9 6.4 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 KFM10976.1 - 9.7e-10 38.4 0.3 7.1e-05 22.5 0.0 3.5 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KFM10976.1 - 2.5e-07 29.2 9.8 0.56 8.2 0.0 5.8 3 3 3 6 6 6 4 Nucleoporin Nup120/160 Proteasome_A_N PF10584.4 KFM10976.1 - 0.00044 19.4 0.2 0.89 8.9 0.0 3.3 3 0 0 3 3 3 2 Proteasome subunit A N-terminal signature Cytochrom_D1 PF02239.11 KFM10976.1 - 0.0016 16.8 0.0 1.4 7.0 0.0 2.9 1 1 2 4 4 4 3 Cytochrome D1 heme domain Gmad1 PF10647.4 KFM10976.1 - 0.094 12.0 0.1 0.46 9.8 0.0 2.1 2 1 1 3 3 3 0 Lipoprotein LpqB beta-propeller domain DUF2415 PF10313.4 KFM10976.1 - 0.11 12.2 0.2 2.9 7.6 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised protein domain (DUF2415) PD40 PF07676.7 KFM10976.1 - 0.14 11.8 0.4 34 4.2 0.0 3.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Glycos_transf_2 PF00535.21 KFM10977.1 - 2e-32 112.1 0.0 3.9e-32 111.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 KFM10977.1 - 7.7e-10 38.8 0.0 1.3e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.1 KFM10977.1 - 6.9e-08 32.5 0.0 1.3e-07 31.6 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 KFM10977.1 - 7.5e-07 28.4 0.0 2.7e-06 26.6 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 KFM10977.1 - 3.7e-06 26.3 0.0 7.9e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase E1-E2_ATPase PF00122.15 KFM10978.1 - 2.9e-56 190.0 0.4 6.1e-56 189.0 0.2 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFM10978.1 - 7e-44 149.5 4.1 7e-44 149.5 2.8 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus ATP_Ca_trans_C PF12424.3 KFM10978.1 - 1.4e-33 115.0 2.1 1e-15 57.8 0.7 2.7 1 1 1 2 2 2 2 Plasma membrane calcium transporter ATPase C terminal Hydrolase PF00702.21 KFM10978.1 - 5e-24 85.9 0.0 6e-23 82.3 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFM10978.1 - 1e-16 60.1 0.0 4.4e-16 58.0 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KFM10978.1 - 1.2e-14 54.9 0.0 2.8e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFM10978.1 - 1.9e-14 53.3 0.0 4.4e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFM10978.1 - 8.1e-07 28.8 1.7 0.00019 21.0 0.3 2.8 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase LRR_8 PF13855.1 KFM10979.1 - 8.6e-23 79.8 8.8 2.8e-11 42.9 0.5 3.5 3 1 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KFM10979.1 - 2.8e-16 58.7 8.2 0.00031 20.3 0.1 4.5 2 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM10979.1 - 1.7e-13 48.5 11.6 0.14 12.3 0.0 7.2 7 0 0 7 7 7 4 Leucine Rich Repeat LRR_5 PF13306.1 KFM10979.1 - 1.8e-06 27.6 0.2 4.5e-05 23.1 0.0 2.5 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) LRR_9 PF14580.1 KFM10979.1 - 2.8e-06 27.0 1.9 0.00025 20.6 0.5 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.1 KFM10979.1 - 3.5e-06 26.5 8.3 9.1 6.6 0.0 6.1 6 0 0 6 6 6 2 Leucine Rich repeat LRR_7 PF13504.1 KFM10979.1 - 1.6e-05 24.3 6.0 0.56 10.6 0.0 6.0 6 0 0 6 6 6 1 Leucine rich repeat LRRNT PF01462.13 KFM10979.1 - 3e-05 23.3 3.3 3e-05 23.3 2.3 2.5 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_8 PF13855.1 KFM10980.1 - 1.4e-34 117.6 26.2 4.5e-12 45.5 4.0 6.1 3 1 3 6 6 6 6 Leucine rich repeat LRR_4 PF12799.2 KFM10980.1 - 3.1e-24 84.0 31.5 4.7e-06 26.1 1.5 7.9 4 3 4 8 8 8 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM10980.1 - 7.8e-20 67.8 27.1 0.22 11.6 0.0 11.5 11 1 1 12 12 12 9 Leucine Rich Repeat LRR_6 PF13516.1 KFM10980.1 - 3.2e-10 38.9 22.7 0.39 10.9 0.1 9.5 8 2 1 9 9 9 3 Leucine Rich repeat LRR_7 PF13504.1 KFM10980.1 - 1.4e-09 36.5 22.3 8.7 7.0 0.1 10.9 11 0 0 11 11 11 3 Leucine rich repeat LRRNT PF01462.13 KFM10980.1 - 1.2e-05 24.6 3.6 1.2e-05 24.6 2.5 3.1 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_5 PF13306.1 KFM10980.1 - 3.9e-05 23.3 2.0 0.0048 16.6 0.3 2.9 2 1 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_9 PF14580.1 KFM10980.1 - 0.0001 21.9 4.6 0.036 13.6 1.9 3.1 1 1 2 3 3 3 2 Leucine-rich repeat LRR_8 PF13855.1 KFM10981.1 - 7.2e-39 131.3 42.3 3.4e-13 49.1 2.7 6.1 2 2 4 7 7 7 6 Leucine rich repeat LRR_4 PF12799.2 KFM10981.1 - 3.3e-30 103.1 32.8 2.4e-08 33.4 0.7 7.5 1 1 6 7 7 7 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM10981.1 - 7.8e-25 83.0 27.6 0.046 13.7 0.2 11.5 9 2 2 11 11 11 9 Leucine Rich Repeat LRR_6 PF13516.1 KFM10981.1 - 2e-14 51.9 29.5 0.18 11.9 0.0 10.9 11 0 0 11 11 11 7 Leucine Rich repeat LRR_7 PF13504.1 KFM10981.1 - 3.7e-12 44.3 27.3 0.39 11.1 0.0 10.7 11 0 0 11 11 11 4 Leucine rich repeat LRRNT PF01462.13 KFM10981.1 - 4.1e-08 32.4 2.3 4.1e-08 32.4 1.6 2.3 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_5 PF13306.1 KFM10981.1 - 1.8e-06 27.6 2.7 0.004 16.8 0.1 3.5 2 2 1 3 3 3 2 Leucine rich repeats (6 copies) LRR_9 PF14580.1 KFM10981.1 - 0.00022 20.8 6.8 0.66 9.5 0.2 3.2 1 1 2 3 3 3 3 Leucine-rich repeat Rota_NS53 PF00981.12 KFM10981.1 - 0.053 12.1 0.0 0.09 11.4 0.0 1.3 1 0 0 1 1 1 0 Rotavirus RNA-binding Protein 53 (NS53) Gemini_AL3 PF01407.12 KFM10982.1 - 0.039 13.4 0.0 0.045 13.2 0.0 1.1 1 0 0 1 1 1 0 Geminivirus AL3 protein LRR_8 PF13855.1 KFM10983.1 - 1.5e-41 139.9 28.6 7.6e-13 48.0 4.2 4.8 3 1 3 6 6 6 5 Leucine rich repeat LRR_4 PF12799.2 KFM10983.1 - 1.4e-27 94.8 26.1 1.9e-08 33.7 1.1 6.0 3 1 4 7 7 7 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM10983.1 - 9.9e-17 58.4 18.2 0.027 14.4 0.2 10.2 10 1 0 10 10 10 4 Leucine Rich Repeat LRR_5 PF13306.1 KFM10983.1 - 4.1e-11 42.6 1.6 3e-05 23.7 0.2 3.1 1 1 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_7 PF13504.1 KFM10983.1 - 2.4e-10 38.8 13.5 0.42 11.0 0.2 8.4 8 0 0 8 8 8 3 Leucine rich repeat LRRNT PF01462.13 KFM10983.1 - 1.2e-09 37.3 5.2 1.2e-09 37.3 3.6 2.9 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.1 KFM10983.1 - 2e-08 33.4 20.4 0.06 13.4 0.0 8.6 9 0 0 9 9 9 2 Leucine Rich repeat LRR_9 PF14580.1 KFM10983.1 - 2e-08 34.0 4.0 0.0035 16.9 0.5 3.0 1 1 3 4 4 4 3 Leucine-rich repeat FNIP PF05725.7 KFM10983.1 - 0.18 11.7 5.8 13 5.8 0.1 3.4 2 1 0 2 2 2 0 FNIP Repeat BTG PF07742.7 KFM10986.1 - 1.9e-32 111.2 0.0 2.4e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 BTG family RhoGEF PF00621.15 KFM10987.1 - 7e-19 68.4 3.6 7e-19 68.4 2.5 2.4 2 1 1 3 3 3 1 RhoGEF domain PH PF00169.24 KFM10987.1 - 0.002 18.3 1.6 0.0074 16.4 0.3 2.5 2 1 0 2 2 2 1 PH domain Imm42 PF15601.1 KFM10987.1 - 0.0024 17.3 2.4 0.014 14.8 0.1 2.6 3 0 0 3 3 3 1 Immunity protein 42 PH_5 PF15405.1 KFM10987.1 - 0.0031 17.4 6.0 0.0047 16.8 0.2 3.0 2 1 1 3 3 3 1 Pleckstrin homology domain PH_10 PF15411.1 KFM10987.1 - 0.0037 17.4 0.2 0.096 12.8 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain FYVE PF01363.16 KFM10988.1 - 6.2e-21 74.0 10.9 3e-20 71.8 7.5 2.3 1 0 0 1 1 1 1 FYVE zinc finger CENP-F_leu_zip PF10473.4 KFM10988.1 - 0.00017 21.4 22.5 0.00017 21.4 15.6 14.6 3 3 11 15 15 15 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IBR PF01485.16 KFM10988.1 - 0.003 17.3 4.7 0.018 14.9 3.2 2.4 1 0 0 1 1 1 1 IBR domain ERM PF00769.14 KFM10988.1 - 0.0033 16.9 18.0 0.0033 16.9 12.4 12.0 1 1 7 10 10 10 1 Ezrin/radixin/moesin family Filament PF00038.16 KFM10988.1 - 0.0035 16.8 63.0 0.0035 16.8 43.6 10.8 1 1 7 9 9 9 4 Intermediate filament protein C1_4 PF07975.7 KFM10988.1 - 2.4 8.2 10.2 2.1 8.3 4.7 2.9 2 0 0 2 2 2 0 TFIIH C1-like domain NUDIX PF00293.23 KFM10989.1 - 1.4e-15 57.1 0.2 1.7e-15 56.8 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain MRP-S32 PF10210.4 KFM10990.1 - 8.8e-41 138.1 1.5 1.1e-40 137.8 1.0 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S32 SH2 PF00017.19 KFM10991.1 - 2.3e-13 49.7 0.0 3.4e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 SH2 domain SOCS_box PF07525.11 KFM10991.1 - 2.6e-13 49.5 0.5 4.9e-13 48.6 0.3 1.5 1 0 0 1 1 1 1 SOCS box CARD PF00619.16 KFM10992.1 - 3.4e-17 62.0 0.1 5.6e-17 61.3 0.1 1.4 1 0 0 1 1 1 1 Caspase recruitment domain Death PF00531.17 KFM10992.1 - 4.5e-13 48.7 0.6 5.9e-11 41.9 0.1 2.3 2 0 0 2 2 2 2 Death domain MDFI PF15316.1 KFM10994.1 - 6.6e-17 62.0 12.6 7.9e-17 61.7 8.8 1.1 1 0 0 1 1 1 1 MyoD family inhibitor DHQ_synthase PF01761.15 KFM10995.1 - 3.6e-57 193.2 0.0 4.4e-57 192.9 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.1 KFM10995.1 - 2e-15 56.7 0.0 4.3e-15 55.7 0.0 1.5 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.14 KFM10995.1 - 6.1e-06 25.1 0.0 9.8e-06 24.4 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DUF3371 PF11851.3 KFM10996.1 - 6.4e-47 159.5 1.0 6.4e-47 159.5 0.7 4.2 3 1 1 4 4 4 1 Domain of unknown function (DUF3371) HLH PF00010.21 KFM10996.1 - 2e-16 59.3 0.5 2e-16 59.3 0.4 2.0 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain 5-FTHF_cyc-lig PF01812.15 KFM10996.1 - 0.05 13.3 6.3 0.18 11.5 0.5 2.3 2 0 0 2 2 2 0 5-formyltetrahydrofolate cyclo-ligase family Ribophorin_I PF04597.9 KFM10996.1 - 0.23 9.9 4.6 0.37 9.2 3.2 1.2 1 0 0 1 1 1 0 Ribophorin I DUF4034 PF13226.1 KFM10996.1 - 0.46 9.5 4.3 0.83 8.6 2.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4034) DUF3338 PF11819.3 KFM10997.1 - 2.7e-60 201.7 7.8 8.4e-60 200.1 5.4 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3338) FERM_C PF09380.5 KFM10997.1 - 2.1e-19 69.5 0.3 1e-18 67.2 0.4 2.1 2 0 0 2 2 2 1 FERM C-terminal PH-like domain FERM_N PF09379.5 KFM10997.1 - 2.3e-15 56.4 0.0 6e-15 55.0 0.0 1.8 1 0 0 1 1 1 1 FERM N-terminal domain FERM_M PF00373.13 KFM10997.1 - 1.1e-09 38.5 5.3 7.5e-09 35.8 0.0 3.4 3 1 0 4 4 4 1 FERM central domain PRA1 PF03208.14 KFM10998.1 - 3.8e-18 65.2 1.6 4.4e-18 65.0 1.1 1.1 1 0 0 1 1 1 1 PRA1 family protein DUF1049 PF06305.6 KFM10998.1 - 0.004 16.6 1.8 0.86 9.1 0.1 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF1049) DUF4446 PF14584.1 KFM10998.1 - 0.0054 16.5 1.8 0.47 10.2 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF4446) Melibiase PF02065.13 KFM10998.1 - 0.077 11.6 0.0 0.09 11.4 0.0 1.1 1 0 0 1 1 1 0 Melibiase DUF3981 PF13139.1 KFM10998.1 - 0.081 12.9 2.9 0.088 12.8 1.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3981) DUF192 PF02643.10 KFM10998.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized ACR, COG1430 Spin-Ssty PF02513.12 KFM10998.1 - 0.11 12.0 0.7 0.22 11.0 0.3 1.7 2 0 0 2 2 2 0 Spin/Ssty Family Halogen_Hydrol PF10112.4 KFM10998.1 - 0.18 11.1 0.9 0.23 10.8 0.1 1.5 1 1 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF3487 PF11990.3 KFM10998.1 - 0.53 9.6 4.5 0.99 8.8 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3487) ThiF PF00899.16 KFM10999.1 - 1.2e-40 138.4 0.1 1.3e-39 135.0 0.0 2.2 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 KFM10999.1 - 1.3e-26 92.1 0.3 2.5e-26 91.2 0.2 1.5 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 KFM10999.1 - 3.8e-23 80.8 0.2 7.6e-23 79.8 0.1 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KFM10999.1 - 4e-12 45.3 0.8 9.5e-12 44.1 0.5 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site MoeZ_MoeB PF05237.8 KFM10999.1 - 8.9e-05 22.0 0.0 0.00021 20.7 0.0 1.6 1 0 0 1 1 1 1 MoeZ/MoeB domain Shikimate_DH PF01488.15 KFM10999.1 - 0.00038 20.5 0.0 0.00071 19.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase UAE_UbL PF14732.1 KFM10999.1 - 0.0017 18.4 0.0 0.003 17.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Pyr_redox PF00070.22 KFM10999.1 - 0.14 12.5 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TMF_TATA_bd PF12325.3 KFM11000.1 - 1.1e-36 125.1 10.8 1.1e-36 125.1 7.5 7.9 2 1 7 9 9 9 3 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 KFM11000.1 - 2.6e-18 65.5 25.3 2.6e-18 65.5 17.5 11.5 6 4 6 13 13 13 4 TATA element modulatory factor 1 DNA binding SlyX PF04102.7 KFM11000.1 - 0.006 16.9 3.6 0.006 16.9 2.5 9.7 5 3 5 11 11 11 3 SlyX DUF563 PF04577.9 KFM11001.1 - 1.1e-24 87.5 0.5 1.7e-24 86.8 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) TAFA PF12020.3 KFM11002.1 - 1.4e-55 185.3 11.4 1.7e-55 185.1 7.9 1.0 1 0 0 1 1 1 1 TAFA family Leader_Trp PF08255.6 KFM11002.1 - 0.093 12.4 0.4 0.35 10.6 0.1 2.0 2 0 0 2 2 2 0 Trp-operon Leader Peptide TAFA PF12020.3 KFM11003.1 - 1.1e-54 182.5 11.9 1.2e-54 182.3 8.3 1.0 1 0 0 1 1 1 1 TAFA family ATP-grasp_2 PF08442.5 KFM11004.1 - 5.8e-76 254.3 1.4 8e-76 253.9 1.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 KFM11004.1 - 9.2e-21 74.0 0.2 2.1e-20 72.8 0.1 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 KFM11004.1 - 4e-10 39.2 0.2 5.5e-10 38.8 0.1 1.2 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 KFM11004.1 - 0.00085 18.9 0.1 0.0015 18.1 0.1 1.5 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 KFM11004.1 - 0.032 13.9 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp PF02222.17 KFM11004.1 - 0.069 12.4 0.1 0.14 11.4 0.1 1.7 1 1 0 1 1 1 0 ATP-grasp domain MFS_1 PF07690.11 KFM11005.1 - 2.4e-44 151.4 25.5 1.1e-37 129.5 19.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KFM11005.1 - 2.5e-07 30.3 12.0 0.016 14.9 0.0 5.2 5 1 1 6 6 6 3 MFS_1 like family MFS_3 PF05977.8 KFM11005.1 - 0.081 11.0 1.1 0.17 9.9 0.0 1.9 2 0 0 2 2 2 0 Transmembrane secretion effector DUF2371 PF10177.4 KFM11005.1 - 0.65 9.8 1.9 4.6 7.1 0.0 2.9 3 1 1 4 4 4 0 Uncharacterised conserved protein (DUF2371) BACK PF07707.10 KFM11006.1 - 2e-31 107.8 2.0 1.4e-30 105.1 0.6 2.4 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_1 PF01344.20 KFM11006.1 - 1.3e-29 101.4 13.9 3.9e-10 39.0 0.3 5.8 6 0 0 6 6 6 4 Kelch motif BTB PF00651.26 KFM11006.1 - 9.2e-29 99.6 0.3 1.9e-28 98.6 0.2 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.1 KFM11006.1 - 5.1e-27 92.8 2.3 4.3e-06 26.6 0.0 5.9 4 1 2 6 6 6 5 Kelch motif Kelch_2 PF07646.10 KFM11006.1 - 3.1e-13 48.9 5.2 3.9e-06 26.4 0.1 5.3 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 KFM11006.1 - 1.2e-12 47.4 0.3 0.0081 15.9 0.0 4.4 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.1 KFM11006.1 - 1.4e-09 37.8 0.6 0.0063 16.6 0.0 4.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 KFM11006.1 - 0.00024 20.9 1.9 22 5.1 0.0 4.5 4 0 0 4 4 4 0 Kelch motif DUF3342 PF11822.3 KFM11006.1 - 0.00089 18.4 0.1 0.0039 16.3 0.0 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF3342) LRR_8 PF13855.1 KFM11007.1 - 6.2e-79 259.6 73.5 3.2e-16 58.8 2.3 8.0 2 1 7 9 9 9 9 Leucine rich repeat I-set PF07679.11 KFM11007.1 - 4.7e-54 180.2 0.0 6.2e-22 77.2 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain LRR_4 PF12799.2 KFM11007.1 - 1.1e-40 136.6 44.4 1.2e-05 24.7 1.6 9.7 2 1 11 13 13 13 13 Leucine Rich repeats (2 copies) Ig_2 PF13895.1 KFM11007.1 - 8.2e-36 121.9 0.0 7.3e-12 45.2 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 KFM11007.1 - 1.4e-28 99.1 0.0 3.3e-10 40.3 0.0 4.4 3 2 0 3 3 3 3 Immunoglobulin domain LRR_5 PF13306.1 KFM11007.1 - 2.3e-28 98.4 0.0 5.7e-09 35.7 0.0 4.0 1 1 3 4 4 4 4 Leucine rich repeats (6 copies) LRR_1 PF00560.28 KFM11007.1 - 4.9e-25 83.7 36.7 0.3 11.2 0.0 15.7 16 0 0 16 16 15 9 Leucine Rich Repeat ig PF00047.20 KFM11007.1 - 1.4e-20 73.1 0.0 1.5e-09 37.8 0.0 4.4 3 2 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 KFM11007.1 - 1.1e-18 67.1 0.0 9.2e-05 22.3 0.0 3.9 3 2 0 3 3 3 3 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM11007.1 - 4.5e-11 42.4 0.0 0.00063 19.5 0.0 3.8 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain LRR_6 PF13516.1 KFM11007.1 - 4.8e-11 41.5 45.5 0.68 10.1 0.1 15.0 15 1 1 16 16 15 3 Leucine Rich repeat LRR_7 PF13504.1 KFM11007.1 - 8.6e-09 34.1 47.2 3.8 8.1 0.2 15.0 15 0 0 15 15 15 1 Leucine rich repeat LRR_9 PF14580.1 KFM11007.1 - 2.5e-08 33.6 6.6 0.14 11.6 0.0 4.6 1 1 3 4 4 4 4 Leucine-rich repeat LRRCT PF01463.19 KFM11007.1 - 0.019 15.2 0.0 0.089 13.1 0.0 2.3 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain Mito_carr PF00153.22 KFM11008.1 - 2.4e-52 174.5 6.4 5.2e-21 74.1 0.5 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein PDZ PF00595.19 KFM11009.1 - 1.2e-66 220.8 5.0 1.4e-14 53.9 0.1 5.4 5 0 0 5 5 5 5 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM11009.1 - 2.6e-32 110.5 0.1 6.9e-06 25.8 0.0 5.6 6 0 0 6 6 6 5 PDZ domain WW PF00397.21 KFM11009.1 - 8.1e-15 54.3 9.6 2.7e-09 36.7 0.3 3.4 3 0 0 3 3 3 2 WW domain Guanylate_kin PF00625.16 KFM11009.1 - 1e-09 38.1 0.0 2e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Guanylate kinase Tricorn_PDZ PF14685.1 KFM11009.1 - 8.3e-09 35.1 4.4 0.066 13.0 0.0 5.1 5 0 0 5 5 5 3 Tricorn protease PDZ domain Serglycin PF04360.7 KFM11009.1 - 0.015 15.0 2.2 0.032 13.9 1.5 1.5 1 0 0 1 1 1 0 Serglycin OB_RNB PF08206.6 KFM11009.1 - 9 5.8 7.8 29 4.2 0.0 4.4 5 0 0 5 5 5 0 Ribonuclease B OB domain GON PF08685.6 KFM11010.1 - 2.5e-84 282.1 1.5 1e-83 280.1 1.1 2.2 1 0 0 1 1 1 1 GON domain TSP_1 PF00090.14 KFM11010.1 - 6.1e-56 186.3 203.5 5.6e-07 29.5 5.2 16.8 17 0 0 17 17 17 13 Thrombospondin type 1 domain ADAM_spacer1 PF05986.9 KFM11010.1 - 8.2e-33 112.6 0.1 1.7e-32 111.6 0.1 1.6 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Reprolysin PF01421.14 KFM11010.1 - 8.5e-29 100.5 0.4 1.6e-28 99.6 0.3 1.5 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.1 KFM11010.1 - 4.2e-16 59.4 2.0 9.2e-16 58.3 1.4 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KFM11010.1 - 4.1e-11 43.4 0.2 4.1e-11 43.4 0.2 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFM11010.1 - 5.5e-10 39.5 1.3 1.3e-09 38.3 0.9 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFM11010.1 - 5.9e-10 39.0 0.3 1.3e-09 37.8 0.2 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like DUF955 PF06114.8 KFM11010.1 - 0.037 13.7 0.1 0.072 12.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF955) RPN7 PF10602.4 KFM11011.1 - 1.6e-62 210.0 2.0 2.3e-62 209.5 1.4 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 KFM11011.1 - 2.7e-18 66.1 0.2 7.4e-18 64.8 0.0 1.8 2 0 0 2 2 2 1 PCI domain DUF1732 PF08340.6 KFM11011.1 - 0.042 13.6 1.3 4.4 7.2 0.4 2.9 2 2 0 2 2 2 0 Domain of unknown function (DUF1732) SCA7 PF08313.7 KFM11012.1 - 1e-27 95.4 3.1 1e-27 95.4 2.1 2.3 2 0 0 2 2 2 1 SCA7, zinc-binding domain DUF3505 PF12013.3 KFM11012.1 - 0.012 15.8 0.5 0.22 11.7 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3505) THOC7 PF05615.8 KFM11013.1 - 4.1e-41 140.4 1.8 4.1e-41 140.4 1.2 2.0 2 0 0 2 2 2 1 Tho complex subunit 7 UPF0193 PF05250.6 KFM11013.1 - 0.0023 17.5 5.6 0.0023 17.5 3.9 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0193) DUF641 PF04859.7 KFM11013.1 - 0.014 15.1 11.7 0.25 11.1 2.5 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Sec8_exocyst PF04048.9 KFM11013.1 - 0.022 14.3 6.7 0.023 14.3 2.2 2.5 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain NRN1 PF15056.1 KFM11013.1 - 0.055 13.4 0.4 0.14 12.1 0.1 1.8 1 1 0 1 1 1 0 Neuritin protein family Spc7 PF08317.6 KFM11013.1 - 0.089 11.4 17.1 0.026 13.1 3.5 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF607 PF04678.8 KFM11013.1 - 0.25 11.2 8.8 0.051 13.4 3.6 1.7 1 1 1 2 2 2 0 Protein of unknown function, DUF607 NPV_P10 PF05531.7 KFM11013.1 - 0.47 10.7 3.3 5.8 7.2 1.6 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1319 PF07028.6 KFM11013.1 - 0.49 10.5 13.4 3.4 7.8 5.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) DUF1664 PF07889.7 KFM11013.1 - 0.94 9.2 9.6 5.6 6.7 2.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.14 KFM11013.1 - 1.1 7.0 11.6 1.3 6.7 8.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AATF-Che1 PF13339.1 KFM11013.1 - 2.2 8.4 14.4 5.1 7.2 4.3 2.2 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor FadA PF09403.5 KFM11013.1 - 3.8 7.5 13.7 1.2 9.1 0.7 2.7 1 1 1 2 2 2 0 Adhesion protein FadA COG2 PF06148.6 KFM11013.1 - 3.9 7.3 12.6 0.44 10.4 1.0 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4168 PF13767.1 KFM11013.1 - 4.4 8.0 10.0 22 5.7 6.9 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4168) EF-hand_8 PF13833.1 KFM11014.1 - 0.00074 19.0 0.0 0.051 13.1 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair S_100 PF01023.14 KFM11014.1 - 0.0037 16.5 0.0 0.0072 15.6 0.0 1.5 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_1 PF00036.27 KFM11014.1 - 0.013 14.7 0.3 0.081 12.2 0.2 2.1 2 0 0 2 2 2 0 EF hand LMP PF04778.7 KFM11014.1 - 0.023 14.4 0.2 0.035 13.8 0.1 1.4 1 0 0 1 1 1 0 LMP repeated region EF-hand_7 PF13499.1 KFM11014.1 - 0.026 14.6 0.1 0.041 14.0 0.1 1.3 1 0 0 1 1 1 0 EF-hand domain pair MARVEL PF01284.18 KFM11015.1 - 2.7e-37 127.8 6.5 3.4e-37 127.4 4.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain Frizzled PF01534.12 KFM11015.1 - 0.00037 19.3 1.4 0.0016 17.2 0.9 1.8 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region DUF588 PF04535.7 KFM11015.1 - 0.0011 18.5 1.6 0.0016 18.0 1.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF588) DUF3816 PF12822.2 KFM11015.1 - 0.04 13.7 0.4 0.15 11.9 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) DUF1129 PF06570.6 KFM11015.1 - 0.087 12.1 0.2 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF4570 PF15134.1 KFM11016.1 - 1.2e-42 144.1 2.0 1.4e-42 143.9 1.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4570) DUF2220 PF09983.4 KFM11016.1 - 0.11 11.6 0.6 0.14 11.3 0.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) HIT PF01230.18 KFM11017.1 - 1.2e-17 64.1 0.0 1.5e-17 63.9 0.0 1.0 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KFM11017.1 - 0.00027 21.1 0.0 0.00031 20.9 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF667 PF05018.8 KFM11019.1 - 2.4e-26 92.1 0.0 5.2e-26 91.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Whirly PF08536.6 KFM11019.1 - 0.038 13.4 0.1 0.084 12.3 0.0 1.5 1 0 0 1 1 1 0 Whirly transcription factor DUF1151 PF06625.6 KFM11021.1 - 1.1e-46 157.5 18.0 1.2e-46 157.3 12.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1151) ACOX PF01756.14 KFM11022.1 - 9.6e-62 207.6 1.5 3.2e-61 205.9 0.3 2.0 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 KFM11022.1 - 3.7e-26 91.8 0.1 6.8e-26 91.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 KFM11022.1 - 3.4e-07 29.6 0.1 6.7e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 KFM11022.1 - 1.3e-06 28.5 0.0 3.4e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HTH_25 PF13413.1 KFM11022.1 - 0.28 10.8 1.3 3 7.5 0.1 3.2 3 1 0 3 3 3 0 Helix-turn-helix domain BTB_2 PF02214.17 KFM11023.1 - 9.3e-22 77.0 0.0 2.3e-21 75.7 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Transket_pyr PF02779.19 KFM11024.1 - 6.1e-45 152.8 0.0 1e-44 152.1 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KFM11024.1 - 8.5e-38 129.0 0.1 1.9e-37 127.9 0.1 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain PX PF00787.19 KFM11025.1 - 1.4e-16 60.3 1.0 4.9e-16 58.5 0.0 2.5 3 0 0 3 3 3 1 PX domain Pkinase PF00069.20 KFM11025.1 - 4.1e-11 42.5 0.0 5.7e-10 38.7 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM11025.1 - 1e-07 31.3 0.1 2.5e-06 26.7 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase WH2 PF02205.15 KFM11025.1 - 1.7e-07 30.5 0.1 3.8e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 WH2 motif DUF566 PF04484.7 KFM11025.1 - 1.9 7.9 12.1 3 7.2 8.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) MaoC_dehydratas PF01575.14 KFM11026.1 - 1.6e-20 72.7 0.0 2e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 KFM11026.1 - 8e-07 28.9 0.0 1.5e-06 28.0 0.0 1.5 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase 4HBT PF03061.17 KFM11026.1 - 0.00034 20.6 0.0 0.00079 19.5 0.0 1.6 1 1 0 1 1 1 1 Thioesterase superfamily RNase_P_Rpp14 PF01900.14 KFM11027.1 - 8.4e-10 38.5 0.0 8.6e-10 38.4 0.0 1.0 1 0 0 1 1 1 1 Rpp14/Pop5 family cNMP_binding PF00027.24 KFM11028.1 - 6.7e-44 147.6 0.0 3.3e-23 81.2 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain DUF627 PF04781.7 KFM11028.1 - 0.059 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF627) DUF3783 PF12646.2 KFM11028.1 - 0.13 12.0 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3783) Mito_carr PF00153.22 KFM11029.1 - 1.2e-63 210.8 0.4 1.8e-25 88.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein IBR PF01485.16 KFM11030.1 - 3e-22 78.2 43.0 3e-13 49.4 4.5 3.7 3 0 0 3 3 3 3 IBR domain zf-C3HC4 PF00097.20 KFM11030.1 - 0.00077 19.0 6.3 0.00077 19.0 4.4 4.1 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM11030.1 - 0.0013 18.7 9.1 0.0013 18.7 6.3 4.0 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM11030.1 - 0.0074 16.0 11.3 0.0074 16.0 7.8 4.0 2 1 1 3 3 3 2 Ring finger domain zf-RING_5 PF14634.1 KFM11030.1 - 0.089 12.5 44.7 0.064 13.0 6.9 3.8 3 0 0 3 3 3 0 zinc-RING finger domain DUF2500 PF10694.4 KFM11030.1 - 0.75 9.8 3.2 0.47 10.4 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) Fz PF01392.17 KFM11031.1 - 3.7e-31 107.8 6.8 3.7e-31 107.8 4.7 1.6 2 0 0 2 2 2 1 Fz domain EF-hand_7 PF13499.1 KFM11032.1 - 1.4e-08 34.7 0.1 3.1e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair 2OG-FeII_Oxy_3 PF13640.1 KFM11032.1 - 1.4e-07 31.9 0.0 3.1e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily EF-hand_1 PF00036.27 KFM11032.1 - 2.8e-07 29.3 0.0 0.0083 15.3 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KFM11032.1 - 2.6e-06 26.8 1.2 0.017 14.9 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain 2OG-FeII_Oxy PF03171.15 KFM11032.1 - 3.6e-06 27.1 0.1 1.6e-05 25.1 0.0 2.1 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily EF-hand_5 PF13202.1 KFM11032.1 - 3.8e-06 25.9 0.1 0.045 13.1 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 KFM11032.1 - 3.3e-05 23.4 0.0 0.018 14.6 0.0 2.8 1 1 1 2 2 2 2 EF-hand domain pair 2OG-FeII_Oxy_4 PF13661.1 KFM11032.1 - 0.027 14.0 0.9 0.099 12.2 0.6 1.9 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DALR_1 PF05746.10 KFM11033.1 - 4.7e-20 71.7 0.0 7.9e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 DALR anticodon binding domain DUF498 PF04430.9 KFM11034.1 - 7.4e-24 83.4 0.0 7.9e-24 83.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) IMPDH PF00478.20 KFM11035.1 - 4.7e-124 413.8 2.8 5.4e-124 413.6 1.9 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 KFM11035.1 - 3.2e-19 68.4 0.1 5.2e-09 35.7 0.0 2.5 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 KFM11035.1 - 2.8e-11 43.1 0.2 5.1e-11 42.2 0.2 1.5 1 0 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 KFM11035.1 - 3e-10 39.4 0.7 4.8e-10 38.8 0.5 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 KFM11035.1 - 2.4e-06 26.9 1.3 0.00041 19.6 0.0 2.3 1 1 1 2 2 2 2 Histidine biosynthesis protein NanE PF04131.9 KFM11035.1 - 2.6e-06 26.5 0.2 5.4e-06 25.5 0.1 1.5 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase ThiG PF05690.9 KFM11035.1 - 0.00032 19.8 2.1 0.0008 18.5 0.9 1.9 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.12 KFM11035.1 - 0.0014 17.6 0.7 0.0028 16.6 0.5 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase Dus PF01207.12 KFM11035.1 - 0.0048 15.7 0.9 0.39 9.4 0.0 2.2 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) Aldolase PF01081.14 KFM11035.1 - 0.009 15.1 0.6 0.7 9.0 0.0 2.7 3 0 0 3 3 3 1 KDPG and KHG aldolase B12-binding PF02310.14 KFM11035.1 - 0.0096 15.7 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 1 B12 binding domain DUF561 PF04481.7 KFM11035.1 - 0.043 12.7 0.3 0.073 12.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF561) DHO_dh PF01180.16 KFM11035.1 - 0.15 10.9 3.8 0.1 11.5 0.2 2.1 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase DUF3504 PF12012.3 KFM11036.1 - 1.4e-63 213.7 0.6 1.4e-63 213.7 0.4 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF3504) CARD PF00619.16 KFM11036.1 - 0.0012 18.6 0.0 0.0033 17.2 0.0 1.7 1 0 0 1 1 1 1 Caspase recruitment domain tRNA-synt_1c PF00749.16 KFM11037.1 - 6.5e-107 356.8 0.0 8.2e-107 356.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KFM11037.1 - 3.5e-49 166.7 0.0 7.2e-49 165.7 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.10 KFM11037.1 - 4.5e-28 97.8 0.0 8.9e-28 96.8 0.0 1.5 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 PF04557.10 KFM11037.1 - 2.4e-27 95.4 1.7 4.4e-27 94.5 1.2 1.5 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 SNF PF00209.13 KFM11038.1 - 9.2e-188 624.9 22.5 1.1e-187 624.7 15.6 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family CCDC71L PF15374.1 KFM11039.1 - 9.2e-160 532.0 19.2 1e-159 531.8 13.3 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 71L Kelch_1 PF01344.20 KFM11041.1 - 1.6e-42 142.8 0.0 5.4e-08 32.2 0.0 7.8 8 0 0 8 8 8 7 Kelch motif Kelch_6 PF13964.1 KFM11041.1 - 2.3e-37 125.6 1.3 5.9e-08 32.5 0.0 7.6 3 3 4 7 7 7 6 Kelch motif Kelch_3 PF13415.1 KFM11041.1 - 1e-29 101.9 0.3 3e-06 27.2 0.0 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.1 KFM11041.1 - 2.4e-29 100.8 0.2 2.1e-05 24.1 0.0 7.5 6 2 2 8 8 8 7 Galactose oxidase, central domain Kelch_2 PF07646.10 KFM11041.1 - 2.7e-19 68.0 0.0 0.0031 17.2 0.0 7.3 7 0 0 7 7 7 4 Kelch motif Kelch_5 PF13854.1 KFM11041.1 - 4.2e-10 39.3 1.6 0.0068 16.3 0.0 5.7 6 0 0 6 6 6 3 Kelch motif HEAT_PBS PF03130.11 KFM11041.1 - 0.43 11.1 2.7 3.3 8.4 0.0 3.3 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat DUF1352 PF07086.7 KFM11043.1 - 4.1e-68 228.6 7.0 4.5e-68 228.5 4.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1352) ARPC4 PF05856.7 KFM11044.1 - 3.7e-60 202.1 7.0 4e-60 202.0 4.8 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Ada3 PF10198.4 KFM11045.1 - 1.1e-24 86.6 16.9 1.1e-23 83.3 9.5 3.1 2 1 0 2 2 2 1 Histone acetyltransferases subunit 3 SUZ PF12752.2 KFM11045.1 - 3.8 8.1 7.3 0.85 10.1 0.5 3.0 3 0 0 3 3 3 0 SUZ domain Pkinase PF00069.20 KFM11046.1 - 2.1e-39 135.2 0.1 9.2e-35 120.0 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFM11046.1 - 1e-15 57.5 0.0 1.3e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFM11046.1 - 0.0015 17.5 0.0 0.0027 16.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KFM11046.1 - 0.0021 17.4 0.0 0.0035 16.6 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.17 KFM11046.1 - 0.012 14.9 1.2 0.012 14.9 0.0 1.5 2 0 0 2 2 2 0 RIO1 family APH PF01636.18 KFM11046.1 - 0.028 14.1 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KFM11046.1 - 0.039 12.9 0.0 0.054 12.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like OGG_N PF07934.7 KFM11047.1 - 2.6e-25 88.6 0.0 3.3e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 KFM11047.1 - 0.0012 19.1 0.0 0.0017 18.6 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Myotub-related PF06602.9 KFM11048.1 - 0.00017 20.4 0.1 0.00032 19.6 0.1 1.4 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 KFM11048.1 - 0.00081 19.6 0.0 0.014 15.6 0.0 2.3 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 KFM11048.1 - 0.008 15.5 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFM11048.1 - 0.12 12.0 0.0 0.97 9.0 0.0 2.2 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain SET PF00856.23 KFM11049.1 - 1.5e-10 41.6 0.1 1.5e-10 41.6 0.1 4.0 3 2 0 3 3 3 1 SET domain Pkinase PF00069.20 KFM11050.1 - 2e-38 132.0 0.0 2.7e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM11050.1 - 9.1e-14 51.1 0.0 4.7e-13 48.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KFM11050.1 - 0.086 11.6 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Plexin_cytopl PF08337.7 KFM11051.1 - 8.1e-253 839.6 0.0 1.1e-252 839.2 0.0 1.1 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain TIG PF01833.19 KFM11051.1 - 3.9e-32 110.0 4.0 5.7e-12 45.4 0.7 6.6 6 1 0 6 6 6 4 IPT/TIG domain Sema PF01403.14 KFM11051.1 - 1.7e-29 102.6 0.0 3e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 Sema domain PSI PF01437.20 KFM11051.1 - 1.5e-16 60.3 50.7 1.2e-10 41.3 10.0 3.6 3 0 0 3 3 3 3 Plexin repeat SseC PF04888.7 KFM11052.1 - 0.013 14.8 6.1 0.15 11.3 0.5 3.0 3 0 0 3 3 3 0 Secretion system effector C (SseC) like family Laminin_II PF06009.7 KFM11052.1 - 0.066 12.9 6.4 3.5 7.3 2.4 2.3 2 0 0 2 2 2 0 Laminin Domain II DUF2730 PF10805.3 KFM11052.1 - 0.073 12.8 2.4 1.8 8.3 0.0 3.6 3 1 0 4 4 4 0 Protein of unknown function (DUF2730) Reo_sigmaC PF04582.7 KFM11052.1 - 0.077 12.1 1.9 0.12 11.5 1.3 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF4231 PF14015.1 KFM11052.1 - 0.5 10.3 0.0 0.5 10.3 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) ACCA PF03255.9 KFM11052.1 - 2.2 7.8 7.7 0.62 9.6 0.0 3.0 2 1 1 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Fez1 PF06818.10 KFM11052.1 - 2.8 7.9 19.3 0.34 10.9 0.8 2.5 2 1 0 2 2 2 0 Fez1 DUF4078 PF13300.1 KFM11053.1 - 3e-23 81.7 8.9 3e-23 81.7 6.2 3.6 4 1 0 4 4 4 1 Domain of unknown function (DUF4078) PDZ PF00595.19 KFM11055.1 - 2.1e-95 312.9 3.0 4.1e-14 52.5 0.0 7.2 7 0 0 7 7 7 7 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM11055.1 - 3.2e-41 139.1 0.7 2.4e-05 24.1 0.0 7.4 7 0 0 7 7 7 7 PDZ domain Tricorn_PDZ PF14685.1 KFM11055.1 - 8e-14 51.2 1.8 0.02 14.6 0.0 6.8 6 0 0 6 6 6 4 Tricorn protease PDZ domain GRASP55_65 PF04495.9 KFM11055.1 - 3.6e-05 23.7 0.0 4 7.4 0.0 4.7 4 1 1 5 5 5 2 GRASP55/65 PDZ-like domain EutA PF06277.6 KFM11055.1 - 0.0026 16.4 0.2 0.087 11.4 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation protein EutA MoaE PF02391.12 KFM11055.1 - 0.005 16.6 1.0 9.3 6.0 0.0 4.2 5 0 0 5 5 5 2 MoaE protein SNF PF00209.13 KFM11056.1 - 3.8e-236 784.5 37.8 4.5e-236 784.3 26.2 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family LSM PF01423.17 KFM11058.1 - 1.9e-19 68.9 0.2 2.6e-19 68.5 0.1 1.2 1 0 0 1 1 1 1 LSM domain vATP-synt_E PF01991.13 KFM11058.1 - 0.12 11.6 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit YfkB PF08756.5 KFM11058.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 YfkB-like domain BHD_3 PF10405.4 KFM11059.1 - 4.2e-31 106.4 0.0 1.2e-30 105.0 0.0 1.8 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.10 KFM11059.1 - 4.5e-27 94.2 0.5 4.5e-27 94.2 0.4 3.9 5 0 0 5 5 5 1 Rad4 transglutaminase-like domain BHD_1 PF10403.4 KFM11059.1 - 2.5e-18 65.3 0.0 6.8e-18 63.9 0.0 1.8 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 KFM11059.1 - 3.6e-18 65.6 0.2 3.6e-18 65.6 0.1 4.2 4 1 0 4 4 4 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 KFM11059.1 - 0.081 13.1 0.0 1.4 9.1 0.0 2.6 2 0 0 2 2 2 0 Transglutaminase-like superfamily DUF1654 PF07867.6 KFM11059.1 - 2.4 7.5 6.4 3.2 7.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) DUF1625 PF07787.7 KFM11060.1 - 5.4e-83 278.0 0.0 7.1e-83 277.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1625) CHCH PF06747.8 KFM11061.1 - 1.1e-09 37.9 7.2 1.8e-09 37.2 5.0 1.4 1 0 0 1 1 1 1 CHCH domain Ndufs5 PF10200.4 KFM11061.1 - 0.018 15.0 0.4 0.023 14.6 0.3 1.2 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa GCK PF07802.6 KFM11061.1 - 0.21 11.7 5.6 0.49 10.5 3.6 1.8 1 1 0 1 1 1 0 GCK domain Laminin_N PF00055.12 KFM11062.1 - 1.9e-47 161.2 0.1 3.1e-47 160.5 0.0 1.3 1 0 0 1 1 1 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.19 KFM11062.1 - 2.5e-24 84.9 74.5 1.4e-09 37.7 6.7 6.4 6 1 1 7 7 7 4 Laminin EGF-like (Domains III and V) NTR PF01759.16 KFM11062.1 - 4.7e-21 74.4 0.3 2.3e-20 72.2 0.1 2.2 2 0 0 2 2 2 1 UNC-6/NTR/C345C module KGK PF08872.5 KFM11062.1 - 0.03 14.4 0.1 0.33 11.1 0.1 2.1 1 1 1 2 2 2 0 KGK domain zf-H2C2_2 PF13465.1 KFM11063.1 - 7.8e-21 73.2 51.8 0.0005 20.2 0.0 8.8 8 1 1 9 9 9 6 Zinc-finger double domain zf-C2H2 PF00096.21 KFM11063.1 - 1.2e-17 63.0 62.0 0.00069 19.8 0.2 9.1 9 0 0 9 9 9 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM11063.1 - 3.7e-15 55.0 56.5 0.0045 17.2 0.1 9.2 9 0 0 9 9 9 7 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM11063.1 - 0.11 12.4 0.1 0.11 12.4 0.1 6.4 7 0 0 7 7 7 0 C2H2-type zinc finger zf-met PF12874.2 KFM11063.1 - 0.6 10.3 28.3 0.59 10.4 0.8 7.3 7 0 0 7 7 7 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 KFM11064.1 - 1.9e-14 53.0 20.4 2.7e-05 24.2 1.1 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM11064.1 - 6.4e-13 48.2 20.3 5.4e-09 35.8 0.7 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM11064.1 - 8.4e-12 44.5 18.8 3.5e-05 23.8 1.0 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 KFM11064.1 - 0.0032 17.6 4.6 0.12 12.6 0.5 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type DUF2225 PF09986.4 KFM11064.1 - 0.028 13.8 0.3 0.09 12.2 0.3 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_6 PF13912.1 KFM11064.1 - 0.046 13.6 2.0 4.5 7.3 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.7 KFM11064.1 - 2.3 8.4 7.5 0.4 10.8 0.7 2.3 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding MgtE PF01769.11 KFM11065.1 - 8.3e-30 103.8 13.6 3.4e-27 95.3 5.5 3.4 3 1 1 4 4 4 2 Divalent cation transporter Sulfotransfer_2 PF03567.9 KFM11066.1 - 1.3e-69 234.7 4.4 1.6e-69 234.4 3.1 1.1 1 0 0 1 1 1 1 Sulfotransferase family DUF4543 PF15076.1 KFM11066.1 - 0.0042 17.0 0.6 0.0082 16.1 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4543) DUF2115 PF09888.4 KFM11066.1 - 0.091 12.8 0.1 0.21 11.6 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) Pyr_redox_2 PF07992.9 KFM11067.1 - 2.2e-37 128.9 0.1 3.1e-37 128.4 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KFM11067.1 - 1.1e-28 99.4 0.0 2.3e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 KFM11067.1 - 6e-16 58.6 4.4 4e-13 49.5 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFM11067.1 - 3.3e-09 37.1 0.0 7.3e-09 35.9 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFM11067.1 - 2e-07 30.2 0.1 1.2e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KFM11067.1 - 0.00063 18.3 0.5 0.0013 17.2 0.2 1.5 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 KFM11067.1 - 0.0011 18.1 0.7 0.0061 15.6 0.1 2.1 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 KFM11067.1 - 0.0011 18.1 0.0 0.0015 17.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 KFM11067.1 - 0.0043 15.9 0.1 0.0043 15.9 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 KFM11067.1 - 0.033 13.0 1.9 0.11 11.3 1.3 1.9 1 1 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_8 PF13450.1 KFM11067.1 - 0.048 13.6 0.5 0.048 13.6 0.4 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF4633 PF15464.1 KFM11067.1 - 0.19 11.5 0.0 0.4 10.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4633) FAD_binding_3 PF01494.14 KFM11067.1 - 1.9 7.4 4.4 2.1 7.3 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain Sema PF01403.14 KFM11068.1 - 7e-54 182.9 0.0 8.8e-54 182.6 0.0 1.1 1 0 0 1 1 1 1 Sema domain MCM PF00493.18 KFM11069.1 - 2.1e-141 470.5 0.0 3.2e-141 469.9 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 KFM11069.1 - 2.5e-26 92.5 23.4 2.5e-26 92.5 16.2 1.9 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 KFM11069.1 - 9.6e-20 71.2 0.6 2.9e-19 69.7 0.4 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KFM11069.1 - 1e-08 34.6 0.0 4.9e-07 29.1 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KFM11069.1 - 4.7e-07 29.4 0.0 3.4e-05 23.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFM11069.1 - 6.5e-07 29.1 0.0 2.8e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 KFM11069.1 - 0.0018 17.8 0.1 1.1 8.6 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA PF00004.24 KFM11069.1 - 0.0025 18.0 0.0 0.007 16.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 KFM11069.1 - 0.0073 16.2 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.1 KFM11069.1 - 0.049 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain CD34_antigen PF06365.7 KFM11070.1 - 9.4e-63 211.5 0.0 1.2e-62 211.1 0.0 1.2 1 0 0 1 1 1 1 CD34/Podocalyxin family Amnionless PF14828.1 KFM11070.1 - 0.13 10.7 0.0 0.19 10.1 0.0 1.1 1 0 0 1 1 1 0 Amnionless Shisa PF13908.1 KFM11070.1 - 0.17 12.0 0.5 0.41 10.8 0.0 1.8 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator BTB PF00651.26 KFM11071.1 - 7.1e-44 148.3 2.8 3.5e-21 75.2 0.0 3.4 2 1 1 3 3 3 3 BTB/POZ domain Ank_5 PF13857.1 KFM11071.1 - 1.2e-10 41.2 0.2 6.5e-08 32.5 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KFM11071.1 - 1.5e-07 31.6 0.0 4.3e-06 26.9 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFM11071.1 - 3.8e-07 29.6 0.0 1.8e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 KFM11071.1 - 3.3e-06 27.4 0.2 1.5e-05 25.3 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM11071.1 - 1.1e-05 25.1 0.2 0.00025 20.9 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat DUF3342 PF11822.3 KFM11071.1 - 0.00017 20.8 1.2 0.014 14.5 0.2 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF3342) BACK PF07707.10 KFM11071.1 - 0.00056 19.7 0.1 0.0018 18.0 0.1 1.9 1 0 0 1 1 1 1 BTB And C-terminal Kelch IFT20 PF14931.1 KFM11071.1 - 0.015 15.1 1.2 0.051 13.4 0.9 1.8 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 Hydrolase_4 PF12146.3 KFM11072.1 - 3.4e-25 87.6 1.0 5.8e-25 86.9 0.7 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_6 PF12697.2 KFM11072.1 - 1.3e-22 80.8 0.0 1.8e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFM11072.1 - 1.6e-18 66.8 0.0 7.1e-18 64.7 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFM11072.1 - 3.1e-10 40.0 0.0 8e-09 35.3 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 KFM11072.1 - 1.2e-05 24.9 0.0 1.8e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Lipase_3 PF01764.20 KFM11072.1 - 1.5e-05 24.6 0.1 3.4e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 3) Thioesterase PF00975.15 KFM11072.1 - 2.1e-05 24.8 0.0 4.4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain DLH PF01738.13 KFM11072.1 - 4.8e-05 22.7 0.0 0.0091 15.2 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 KFM11072.1 - 5.3e-05 22.7 0.1 0.26 10.7 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase PGAP1 PF07819.8 KFM11072.1 - 9.9e-05 22.0 0.2 0.0021 17.6 0.1 2.3 2 1 0 2 2 2 1 PGAP1-like protein Peptidase_S9 PF00326.16 KFM11072.1 - 0.00013 21.3 0.0 0.057 12.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 KFM11072.1 - 0.025 14.1 0.1 0.11 12.0 0.1 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold FSH1 PF03959.8 KFM11072.1 - 0.064 12.6 0.0 0.27 10.6 0.0 1.9 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DUF1350 PF07082.6 KFM11072.1 - 0.066 12.2 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1350) LIP PF03583.9 KFM11072.1 - 0.12 11.5 0.0 0.69 9.0 0.0 1.9 2 0 0 2 2 2 0 Secretory lipase BACK PF07707.10 KFM11073.1 - 2.5e-29 101.1 1.4 2.5e-29 101.1 1.0 2.6 3 0 0 3 3 3 1 BTB And C-terminal Kelch Kelch_1 PF01344.20 KFM11073.1 - 4.5e-29 99.7 3.2 2.9e-10 39.5 0.0 4.9 4 1 0 4 4 4 4 Kelch motif Kelch_6 PF13964.1 KFM11073.1 - 2.2e-26 90.8 4.0 9.6e-09 35.0 0.0 5.4 4 2 2 6 6 6 3 Kelch motif BTB PF00651.26 KFM11073.1 - 2.4e-23 82.2 2.6 2.4e-23 82.2 1.8 1.8 2 0 0 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.10 KFM11073.1 - 1.6e-14 52.9 4.3 9.9e-07 28.2 0.0 4.9 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.1 KFM11073.1 - 1.2e-12 47.5 2.4 0.0017 18.4 0.0 4.4 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_4 PF13418.1 KFM11073.1 - 1.6e-11 43.8 5.5 0.00012 21.7 0.0 4.8 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 KFM11073.1 - 7.4e-11 41.7 0.2 9.2e-05 22.3 0.0 4.2 4 0 0 4 4 4 2 Kelch motif DUF3342 PF11822.3 KFM11073.1 - 1.1e-05 24.8 2.0 1.1e-05 24.8 1.4 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF3342) SecY PF00344.15 KFM11074.1 - 2.5e-96 322.6 13.7 3.5e-96 322.1 9.5 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 KFM11074.1 - 1.4e-19 69.2 0.3 4.2e-19 67.7 0.2 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p Phage_holin_1 PF04531.8 KFM11074.1 - 0.035 14.1 0.1 3.3 7.8 0.0 3.4 3 0 0 3 3 3 0 Bacteriophage holin YlaH PF14036.1 KFM11074.1 - 0.035 14.1 3.1 0.46 10.5 0.1 3.1 3 0 0 3 3 3 0 YlaH-like protein TIP49 PF06068.8 KFM11075.1 - 7.7e-185 614.2 0.5 8.8e-185 614.0 0.3 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 KFM11075.1 - 5.7e-14 51.7 2.3 4.4e-08 32.4 0.0 3.2 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 KFM11075.1 - 4.4e-13 49.5 0.4 2.5e-08 34.1 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFM11075.1 - 1.6e-07 31.5 0.0 0.00081 19.4 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 KFM11075.1 - 2.5e-06 27.6 0.1 0.031 14.4 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KFM11075.1 - 1.3e-05 24.8 0.0 3.2e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 KFM11075.1 - 4.1e-05 23.3 0.1 0.003 17.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KFM11075.1 - 4.7e-05 22.8 0.0 0.00013 21.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 KFM11075.1 - 0.00019 20.9 0.1 0.17 11.3 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain Mg_chelatase PF01078.16 KFM11075.1 - 0.00051 19.2 0.2 0.028 13.5 0.1 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KFM11075.1 - 0.00052 19.4 0.1 0.001 18.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 KFM11075.1 - 0.00068 18.7 0.6 0.0014 17.8 0.2 1.6 2 0 0 2 2 1 1 Zeta toxin AAA_18 PF13238.1 KFM11075.1 - 0.0012 19.1 0.8 0.015 15.5 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 KFM11075.1 - 0.0015 19.3 0.0 0.0038 18.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KFM11075.1 - 0.0016 18.4 0.0 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFM11075.1 - 0.0034 17.2 0.0 0.0099 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 KFM11075.1 - 0.006 15.8 0.1 0.018 14.2 0.1 1.8 1 0 0 1 1 1 1 PhoH-like protein DnaB_C PF03796.10 KFM11075.1 - 0.007 15.2 0.0 0.013 14.3 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_14 PF13173.1 KFM11075.1 - 0.0088 15.9 0.0 1.1 9.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KFM11075.1 - 0.011 15.4 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Parvo_NS1 PF01057.12 KFM11075.1 - 0.014 14.3 0.1 0.032 13.0 0.0 1.5 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 UPF0079 PF02367.12 KFM11075.1 - 0.015 14.8 0.0 0.053 13.1 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 KFM11075.1 - 0.021 14.4 0.0 0.064 12.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 KFM11075.1 - 0.026 13.6 0.9 0.16 11.1 0.0 2.5 3 0 0 3 3 3 0 KaiC DUF2075 PF09848.4 KFM11075.1 - 0.028 13.4 0.0 0.044 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DNA_pol3_delta2 PF13177.1 KFM11075.1 - 0.034 13.8 0.0 0.54 9.8 0.0 2.3 1 1 0 1 1 1 0 DNA polymerase III, delta subunit NTPase_1 PF03266.10 KFM11075.1 - 0.035 13.8 0.1 0.09 12.4 0.0 1.8 2 0 0 2 2 1 0 NTPase ResIII PF04851.10 KFM11075.1 - 0.039 13.7 0.1 0.57 9.9 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 KFM11075.1 - 0.074 13.2 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 KFM11075.1 - 0.13 12.2 0.0 2 8.4 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain GTP_EFTU PF00009.22 KFM11076.1 - 2.6e-09 36.7 0.1 5.3e-09 35.7 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 KFM11076.1 - 3.4e-09 36.6 0.1 8e-09 35.4 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 cobW PF02492.14 KFM11076.1 - 0.00018 21.0 0.8 0.00029 20.3 0.6 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU_D4 PF14578.1 KFM11076.1 - 0.0011 18.6 0.0 0.0047 16.5 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Ribophorin_I PF04597.9 KFM11077.1 - 9.8e-138 459.2 7.4 1.3e-137 458.8 5.1 1.2 1 0 0 1 1 1 1 Ribophorin I DNA_repr_REX1B PF14966.1 KFM11077.1 - 0.0029 17.9 0.9 0.005 17.1 0.2 1.7 2 0 0 2 2 2 1 DNA repair REX1-B FliD_C PF07195.7 KFM11077.1 - 0.0089 15.3 0.5 0.015 14.6 0.3 1.3 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 C-terminus OmpH PF03938.9 KFM11077.1 - 0.024 14.5 0.5 0.037 13.9 0.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HALZ PF02183.13 KFM11077.1 - 0.26 11.0 2.9 0.18 11.5 0.4 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper IncA PF04156.9 KFM11077.1 - 0.36 10.4 3.8 0.6 9.6 2.6 1.3 1 0 0 1 1 1 0 IncA protein Ras PF00071.17 KFM11078.1 - 1.6e-58 196.6 0.1 1.9e-58 196.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM11078.1 - 6.8e-19 68.5 0.0 1.2e-18 67.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM11078.1 - 2.1e-13 49.8 0.1 2.5e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFM11078.1 - 2e-07 30.9 0.0 3.7e-07 30.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFM11078.1 - 5.3e-07 29.0 0.0 6.9e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFM11078.1 - 1.6e-06 27.7 0.0 4.6e-05 22.9 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KFM11078.1 - 0.00029 20.9 0.0 0.00058 20.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KFM11078.1 - 0.00092 18.4 0.0 0.0016 17.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 KFM11078.1 - 0.0012 17.9 0.3 0.016 14.2 0.0 2.1 2 0 0 2 2 2 1 Septin NTPase_1 PF03266.10 KFM11078.1 - 0.0027 17.4 0.1 0.0051 16.5 0.0 1.5 2 0 0 2 2 2 1 NTPase PduV-EutP PF10662.4 KFM11078.1 - 0.0035 16.8 0.1 0.088 12.2 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 KFM11078.1 - 0.0038 16.6 0.1 0.016 14.6 0.0 1.9 1 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 KFM11078.1 - 0.0042 16.6 0.4 0.15 11.5 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 KFM11078.1 - 0.0052 16.5 0.5 0.01 15.5 0.0 1.6 2 0 0 2 2 2 1 Archaeal ATPase AAA_24 PF13479.1 KFM11078.1 - 0.0052 16.3 0.1 0.0097 15.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFM11078.1 - 0.0074 16.2 0.1 0.037 14.0 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain MobB PF03205.9 KFM11078.1 - 0.01 15.5 0.1 0.021 14.4 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 KFM11078.1 - 0.011 15.3 0.0 0.035 13.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) SRPRB PF09439.5 KFM11078.1 - 0.013 14.7 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_10 PF12846.2 KFM11078.1 - 0.018 14.4 0.2 0.028 13.8 0.1 1.4 1 1 0 1 1 1 0 AAA-like domain NACHT PF05729.7 KFM11078.1 - 0.058 13.0 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 KFM11078.1 - 0.074 12.9 0.2 0.15 11.9 0.0 1.8 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.22 KFM11078.1 - 0.15 12.4 0.1 0.41 10.9 0.0 1.7 2 0 0 2 2 2 0 ABC transporter Histone PF00125.19 KFM11079.1 - 3.9e-27 94.1 0.0 4.9e-27 93.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFM11079.1 - 3.6e-05 23.7 0.0 4.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF159 PF02586.9 KFM11080.1 - 4.1e-45 153.8 0.0 6.2e-45 153.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 Adaptin_N PF01602.15 KFM11081.1 - 1e-133 446.4 10.4 1.3e-133 446.1 7.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 KFM11081.1 - 2.6e-58 196.1 0.3 6.8e-58 194.7 0.2 1.8 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 KFM11081.1 - 7.5e-15 54.9 1.7 0.004 17.3 0.1 6.5 1 1 6 7 7 7 5 HEAT repeats HEAT PF02985.17 KFM11081.1 - 9.3e-08 31.5 5.0 3.6 7.9 0.0 7.4 9 0 0 9 9 9 2 HEAT repeat HEAT_EZ PF13513.1 KFM11081.1 - 4.4e-06 26.9 2.3 0.011 16.1 0.0 3.6 3 1 1 4 4 4 2 HEAT-like repeat Cnd1 PF12717.2 KFM11081.1 - 0.00067 19.5 9.0 1 9.2 0.0 4.4 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.11 KFM11081.1 - 0.062 13.7 1.3 24 5.7 0.0 4.6 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Arm PF00514.18 KFM11081.1 - 0.1 12.4 0.0 11 5.9 0.0 4.3 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Peptidase_M16 PF00675.15 KFM11082.1 - 4.9e-49 165.9 0.1 7.9e-49 165.2 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KFM11082.1 - 6.6e-39 133.4 0.0 3.5e-38 131.1 0.0 2.0 2 0 0 2 2 2 1 Peptidase M16 inactive domain DUF2013 PF09431.5 KFM11083.1 - 1.1e-38 132.0 0.5 2.7e-38 130.8 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) DUF1646 PF07854.7 KFM11083.1 - 0.11 11.5 0.3 0.33 10.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1646) IPK PF03770.11 KFM11084.1 - 6.5e-65 218.4 0.5 1.4e-64 217.3 0.4 1.6 1 0 0 1 1 1 1 Inositol polyphosphate kinase Abhydrolase_6 PF12697.2 KFM11085.1 - 1.5e-37 129.6 0.0 2e-37 129.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFM11085.1 - 1.5e-17 63.7 0.0 3e-16 59.5 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFM11085.1 - 9.7e-17 61.2 0.0 8.5e-10 38.5 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Ndr PF03096.9 KFM11085.1 - 1.1e-05 24.0 0.0 7.2e-05 21.3 0.0 2.0 1 1 0 1 1 1 1 Ndr family Lipase PF00151.14 KFM11085.1 - 0.00031 20.0 0.0 0.00045 19.5 0.0 1.2 1 0 0 1 1 1 1 Lipase DUF1057 PF06342.7 KFM11085.1 - 0.00045 19.1 0.0 0.00059 18.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) DLH PF01738.13 KFM11085.1 - 0.0014 17.9 0.0 0.082 12.1 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family UPF0227 PF05728.7 KFM11085.1 - 0.003 17.2 0.2 2.9 7.5 0.0 2.4 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0227) FSH1 PF03959.8 KFM11085.1 - 0.0066 15.9 0.1 0.7 9.2 0.0 2.5 2 1 1 3 3 3 1 Serine hydrolase (FSH1) Thioesterase PF00975.15 KFM11085.1 - 0.014 15.6 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain DUF2048 PF09752.4 KFM11085.1 - 0.041 12.7 0.0 0.39 9.5 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) Abhydrolase_3 PF07859.8 KFM11085.1 - 0.058 12.9 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Exo_endo_phos PF03372.18 KFM11086.1 - 3.8e-15 56.4 0.0 4.6e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KFM11086.1 - 0.016 14.8 0.0 0.031 13.9 0.0 1.6 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Filamin PF00630.14 KFM11087.1 - 0 1270.3 52.6 4e-20 72.2 0.1 24.1 24 0 0 24 24 24 24 Filamin/ABP280 repeat Big_1 PF02369.11 KFM11087.1 - 2.2e-20 72.4 3.3 0.054 13.4 0.1 13.5 15 0 0 15 15 14 4 Bacterial Ig-like domain (group 1) CH PF00307.26 KFM11087.1 - 2.6e-17 62.8 0.0 1.9e-15 56.8 0.0 2.4 2 0 0 2 2 2 1 Calponin homology (CH) domain Y_Y_Y PF07495.8 KFM11087.1 - 1.2e-14 53.7 26.0 0.51 10.1 0.0 14.0 16 0 0 16 16 16 4 Y_Y_Y domain Big_3_4 PF13754.1 KFM11087.1 - 2.3e-06 27.8 44.0 0.43 10.9 0.1 14.7 17 1 1 18 18 18 2 Bacterial Ig-like domain (group 3) YtkA PF13115.1 KFM11087.1 - 6.1e-05 23.2 17.1 1.7 9.0 0.1 10.9 14 0 0 14 14 12 1 YtkA-like BatD PF13584.1 KFM11087.1 - 8.9e-05 21.2 0.9 0.64 8.5 0.0 4.4 5 0 0 5 5 5 2 Oxygen tolerance PapC_N PF13954.1 KFM11087.1 - 0.00049 19.6 0.0 2.3 7.7 0.0 5.6 6 0 0 6 6 6 1 PapC N-terminal domain EMP24_GP25L PF01105.19 KFM11087.1 - 0.00084 19.1 0.4 1.1e+02 2.4 0.0 7.3 9 1 0 10 10 10 0 emp24/gp25L/p24 family/GOLD DUF1214 PF06742.6 KFM11087.1 - 0.0012 19.2 0.4 39 4.7 0.0 6.2 7 0 0 7 7 6 0 Protein of unknown function (DUF1214) DUF2141 PF09912.4 KFM11087.1 - 0.0014 18.3 4.2 20 4.9 0.0 7.4 8 1 1 9 9 9 0 Uncharacterized protein conserved in bacteria (DUF2141) FHA PF00498.21 KFM11088.1 - 1.2e-16 60.6 0.1 4.6e-16 58.7 0.0 2.1 2 0 0 2 2 2 1 FHA domain HrpB7 PF09486.5 KFM11088.1 - 0.01 15.7 0.5 0.01 15.7 0.4 6.4 3 1 1 5 5 5 0 Bacterial type III secretion protein (HrpB7) SecIII_SopE_N PF05364.9 KFM11088.1 - 0.17 11.7 6.6 1 9.2 0.5 3.4 3 0 0 3 3 3 0 Salmonella type III secretion SopE effector N-terminus SPA PF08616.5 KFM11089.1 - 9.2e-16 57.5 0.3 2.7e-14 52.8 0.0 2.5 2 0 0 2 2 2 1 Stabilization of polarity axis DENN PF02141.16 KFM11089.1 - 2.1e-06 27.5 5.9 2.5e-06 27.3 2.4 2.3 2 1 0 2 2 2 1 DENN (AEX-3) domain Avl9 PF09794.4 KFM11089.1 - 0.0022 16.5 0.0 0.0039 15.7 0.0 1.4 1 0 0 1 1 1 1 Transport protein Avl9 RAM PF15320.1 KFM11089.1 - 0.15 12.3 0.2 0.38 11.0 0.1 1.6 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein Arf PF00025.16 KFM11090.1 - 5.7e-73 243.8 0.2 6.2e-73 243.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KFM11090.1 - 1.3e-14 53.8 0.0 1.5e-14 53.6 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 KFM11090.1 - 1.9e-14 53.4 0.0 2.1e-14 53.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KFM11090.1 - 3.6e-11 42.6 0.0 3.7e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KFM11090.1 - 5.5e-11 41.7 0.6 9.8e-10 37.6 0.1 2.2 1 1 1 2 2 2 1 G-protein alpha subunit Miro PF08477.8 KFM11090.1 - 1.9e-08 34.8 0.0 2.8e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KFM11090.1 - 5.3e-06 26.3 0.0 6.8e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 KFM11090.1 - 0.014 14.5 0.1 0.019 14.0 0.1 1.4 1 1 0 1 1 1 0 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 KFM11090.1 - 0.02 14.3 0.2 0.089 12.2 0.0 1.8 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 KFM11090.1 - 0.13 12.1 0.2 0.28 11.0 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KFM11090.1 - 0.22 11.7 1.1 2.7 8.2 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KFM11090.1 - 0.27 11.1 1.1 2.2 8.2 0.0 2.0 1 1 0 2 2 2 0 AAA domain Exo_endo_phos PF03372.18 KFM11091.1 - 2.3e-21 76.8 0.0 2.9e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KFM11091.1 - 0.00028 20.4 0.0 0.00054 19.5 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Dynein_heavy PF03028.10 KFM11092.1 - 2e-243 809.5 0.0 4.2e-243 808.5 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 KFM11092.1 - 3e-126 421.2 13.1 1.3e-125 419.1 9.1 2.2 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 KFM11092.1 - 6.6e-94 313.7 1.1 1.1e-93 313.0 0.2 1.9 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 KFM11092.1 - 1.8e-69 233.7 0.1 8.2e-69 231.5 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.2 KFM11092.1 - 9.2e-56 188.9 0.2 1.8e-55 187.9 0.2 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 MT PF12777.2 KFM11092.1 - 3.5e-50 170.6 9.2 6.6e-50 169.7 6.4 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 KFM11092.1 - 1.4e-31 109.0 2.1 3.3e-30 104.6 1.5 2.6 1 1 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_5 PF07728.9 KFM11092.1 - 4.5e-19 68.5 0.0 5.3e-06 26.1 0.0 5.6 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KFM11092.1 - 2.8e-08 33.9 0.3 0.42 10.5 0.0 5.5 5 0 0 5 5 5 2 AAA ATPase domain AAA PF00004.24 KFM11092.1 - 3.1e-07 30.6 7.0 0.031 14.4 0.0 5.9 6 0 0 6 6 6 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KFM11092.1 - 6.2e-05 23.8 0.0 0.021 15.6 0.0 4.7 4 0 0 4 4 4 1 AAA domain AAA_22 PF13401.1 KFM11092.1 - 0.00057 20.0 0.1 5 7.2 0.0 5.1 5 0 0 5 5 4 1 AAA domain RNA_helicase PF00910.17 KFM11092.1 - 0.0006 19.9 0.5 4.9 7.3 0.0 4.3 4 0 0 4 4 3 1 RNA helicase AAA_19 PF13245.1 KFM11092.1 - 0.0053 16.4 0.1 1.3 8.8 0.1 3.0 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 KFM11092.1 - 0.024 14.9 0.0 3.9 7.7 0.0 4.5 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.1 KFM11092.1 - 0.06 12.9 0.1 4.5 6.8 0.1 3.2 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.1 KFM11092.1 - 0.23 11.0 0.6 5.5 6.5 0.0 3.1 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_25 PF13481.1 KFM11092.1 - 0.3 10.4 0.2 9.1 5.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 KFM11092.1 - 0.32 10.8 0.1 33 4.3 0.0 3.0 2 0 0 2 2 2 0 AAA domain Ank_2 PF12796.2 KFM11093.1 - 1.1e-63 211.5 13.0 7.3e-15 55.0 0.0 5.1 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KFM11093.1 - 1.1e-47 157.5 15.6 2.3e-07 30.3 0.1 10.6 11 0 0 11 11 11 9 Ankyrin repeat Ank_3 PF13606.1 KFM11093.1 - 8.3e-41 133.9 13.5 4.3e-05 23.3 0.0 10.6 10 0 0 10 10 10 8 Ankyrin repeat Ank_4 PF13637.1 KFM11093.1 - 9.4e-38 127.9 9.1 1.1e-11 44.8 0.0 7.7 4 2 6 10 10 10 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM11093.1 - 1.7e-27 94.8 15.5 4.9e-06 26.6 0.1 8.6 4 2 5 9 9 9 8 Ankyrin repeats (many copies) SOCS_box PF07525.11 KFM11093.1 - 9.3e-14 51.0 5.8 2.2e-13 49.7 4.1 1.7 1 0 0 1 1 1 1 SOCS box PID PF00640.18 KFM11094.1 - 5e-12 45.9 0.0 5e-12 45.9 0.0 2.9 3 0 0 3 3 3 1 Phosphotyrosine interaction domain (PTB/PID) PH PF00169.24 KFM11094.1 - 4.9e-06 26.6 0.0 3.9e-05 23.8 0.0 2.4 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 KFM11094.1 - 0.0095 16.0 0.7 0.068 13.3 0.0 2.7 3 0 0 3 3 3 1 Pleckstrin homology domain DUF948 PF06103.6 KFM11094.1 - 1.6 8.6 6.0 17 5.3 0.9 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Homeobox PF00046.24 KFM11095.1 - 4.5e-24 83.8 2.3 6.2e-24 83.3 0.8 1.8 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 KFM11095.1 - 0.0016 18.1 0.1 0.0037 16.9 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain DUF3437 PF11919.3 KFM11095.1 - 0.048 13.3 0.5 5.9 6.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) SEFIR PF08357.6 KFM11096.1 - 8.3e-57 191.4 1.0 1.7e-56 190.4 0.7 1.5 1 0 0 1 1 1 1 SEFIR domain fn3 PF00041.16 KFM11096.1 - 0.011 15.8 0.0 1.6 8.8 0.0 2.7 2 0 0 2 2 2 0 Fibronectin type III domain DUF2141 PF09912.4 KFM11096.1 - 0.073 12.7 0.0 0.25 11.0 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2141) TIR_2 PF13676.1 KFM11096.1 - 0.087 12.9 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 TIR domain DUF1863 PF08937.6 KFM11096.1 - 0.14 12.1 0.2 0.49 10.4 0.2 1.8 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) RhoGEF PF00621.15 KFM11097.1 - 1.1e-39 136.1 0.0 2.1e-39 135.2 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 KFM11097.1 - 4e-08 33.2 0.3 2.5e-07 30.6 0.2 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KFM11097.1 - 3.5e-05 23.9 0.0 7.7e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 PH domain PilN PF05137.8 KFM11097.1 - 0.071 12.9 0.0 0.42 10.4 0.0 2.2 2 0 0 2 2 2 0 Fimbrial assembly protein (PilN) zf-Di19 PF05605.7 KFM11097.1 - 0.19 11.8 2.1 0.22 11.6 0.2 2.0 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF3715 PF12509.3 KFM11098.1 - 3.2e-61 205.9 0.0 1.1e-60 204.2 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3715) CCDC66 PF15236.1 KFM11099.1 - 1.7e-56 190.1 40.0 1.7e-56 190.1 27.7 5.1 5 1 2 7 7 7 1 Coiled-coil domain-containing protein 66 wnt PF00110.14 KFM11100.1 - 2.4e-119 398.1 24.6 2.7e-119 397.9 17.0 1.0 1 0 0 1 1 1 1 wnt family VWA_N PF08399.6 KFM11101.1 - 2.2e-41 141.3 0.3 5.4e-41 140.0 0.2 1.7 1 0 0 1 1 1 1 VWA N-terminal Cache_1 PF02743.13 KFM11101.1 - 1.3e-30 104.7 0.2 2.1e-29 100.8 0.0 2.9 3 0 0 3 3 3 1 Cache domain VWA_2 PF13519.1 KFM11101.1 - 4.9e-16 59.3 0.0 8.7e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 KFM11101.1 - 1.3e-15 57.3 0.0 2.2e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KFM11101.1 - 5.5e-13 49.0 0.0 1e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 KFM11101.1 - 0.024 13.7 0.0 0.043 12.9 0.0 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein LRR_8 PF13855.1 KFM11102.1 - 1.9e-23 81.9 18.7 5.3e-14 51.7 2.7 3.9 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 KFM11102.1 - 1.5e-12 46.8 18.4 3.5e-06 26.4 1.9 4.1 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFM11102.1 - 5.1e-08 32.6 0.7 4.7e-06 26.3 0.5 2.3 2 0 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_1 PF00560.28 KFM11102.1 - 2.4e-07 29.8 17.3 0.01 15.7 0.2 5.6 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_9 PF14580.1 KFM11102.1 - 9.7e-06 25.2 4.0 0.0093 15.5 0.6 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.1 KFM11102.1 - 0.00044 20.0 9.2 0.79 9.9 0.1 4.7 5 0 0 5 5 5 2 Leucine Rich repeat LRR_7 PF13504.1 KFM11102.1 - 0.0013 18.6 13.3 0.17 12.1 0.1 5.4 5 0 0 5 5 5 2 Leucine rich repeat LRRNT PF01462.13 KFM11102.1 - 0.06 12.8 0.7 0.06 12.8 0.5 2.1 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain DUF2763 PF10961.3 KFM11103.1 - 5.3e-27 94.0 0.2 6.2e-27 93.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2763) GMC_oxred_N PF00732.14 KFM11104.1 - 7.3e-96 320.7 0.0 9.9e-96 320.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFM11104.1 - 9.6e-42 142.6 0.0 1.6e-41 141.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 KFM11104.1 - 6.7e-05 21.9 0.0 0.0001 21.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 KFM11104.1 - 0.001 18.0 0.0 0.038 12.8 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFM11104.1 - 0.0022 17.9 0.0 0.0093 15.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KFM11104.1 - 0.0032 16.3 0.0 0.11 11.2 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 KFM11104.1 - 0.0051 16.9 0.0 1.9 8.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFM11104.1 - 0.065 13.0 0.0 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ion_trans PF00520.26 KFM11105.1 - 4.9e-216 711.4 76.8 8.2e-65 217.8 6.6 4.6 4 0 0 4 4 4 4 Ion transport protein Ca_chan_IQ PF08763.6 KFM11105.1 - 3.3e-19 67.8 1.9 1.2e-18 65.9 1.3 2.1 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain PKD_channel PF08016.7 KFM11105.1 - 6.7e-09 34.6 5.3 6.7e-09 34.6 3.7 9.0 7 3 1 8 8 8 5 Polycystin cation channel DCP1 PF06058.8 KFM11106.1 - 1.4e-34 118.7 0.1 2.5e-34 117.9 0.1 1.4 1 0 0 1 1 1 1 Dcp1-like decapping family Transketolase_N PF00456.16 KFM11107.1 - 3.9e-81 272.4 0.0 6.5e-81 271.7 0.0 1.4 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KFM11107.1 - 9.4e-41 139.2 0.0 1.9e-40 138.2 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KFM11107.1 - 3.5e-29 101.2 0.4 7.9e-29 100.1 0.3 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.15 KFM11107.1 - 8.7e-09 34.5 0.0 2.4e-08 33.0 0.0 1.8 1 1 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 KFM11107.1 - 4.2e-06 26.4 0.2 0.00017 21.1 0.1 3.2 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 KFM11107.1 - 4.7e-06 25.7 0.0 0.00043 19.2 0.0 2.5 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase XFP_N PF09364.5 KFM11107.1 - 0.00036 19.1 0.2 0.0026 16.3 0.0 2.0 1 1 1 2 2 2 1 XFP N-terminal domain FancD2 PF14631.1 KFM11108.1 - 0 2546.4 22.5 0 2546.2 15.6 1.0 1 0 0 1 1 1 1 Fanconi anaemia protein FancD2 nuclease DUF106 PF01956.11 KFM11109.1 - 2.5e-36 124.7 4.6 4.6e-36 123.8 0.3 2.1 2 0 0 2 2 2 2 Integral membrane protein DUF106 GyrI-like PF06445.10 KFM11110.1 - 9.7e-06 25.6 0.0 1.4e-05 25.1 0.0 1.3 1 1 0 1 1 1 1 GyrI-like small molecule binding domain NHR2 PF08788.6 KFM11112.1 - 2.2e-35 119.9 10.2 4.6e-35 118.9 7.1 1.6 1 0 0 1 1 1 1 NHR2 domain like TAFH PF07531.9 KFM11112.1 - 4.8e-34 115.8 1.1 8.6e-34 115.0 0.8 1.4 1 0 0 1 1 1 1 NHR1 homology to TAF zf-MYND PF01753.13 KFM11112.1 - 5.9e-08 32.4 15.8 5.9e-08 32.4 10.9 2.2 2 0 0 2 2 2 1 MYND finger vATP-synt_E PF01991.13 KFM11112.1 - 0.82 8.9 10.2 1.4 8.1 7.1 1.3 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit HMG_box PF00505.14 KFM11113.1 - 9.4e-11 41.8 0.0 1.9e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFM11113.1 - 3.9e-09 36.7 0.1 7.5e-09 35.8 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain YABBY PF04690.8 KFM11113.1 - 0.064 13.5 0.6 0.15 12.3 0.4 1.8 1 0 0 1 1 1 0 YABBY protein Mitofilin PF09731.4 KFM11113.1 - 0.2 10.3 5.5 0.25 9.9 3.8 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein MRI PF15325.1 KFM11113.1 - 1.8 9.5 7.4 0.45 11.4 1.9 2.4 2 0 0 2 2 2 0 Modulator of retrovirus infection Glyco_hydro_47 PF01532.15 KFM11115.1 - 1.9e-129 432.2 0.0 2.3e-129 431.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF3689 PF12463.3 KFM11116.1 - 6.1e-133 442.2 13.5 9.2e-133 441.6 9.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3689) Myosin_tail_1 PF01576.14 KFM11117.1 - 0 1113.1 274.9 0 1096.4 144.0 3.1 1 1 2 3 3 3 3 Myosin tail Myosin_head PF00063.16 KFM11117.1 - 5.2e-271 900.6 0.4 5.2e-271 900.6 0.3 3.6 4 0 0 4 4 4 1 Myosin head (motor domain) Myosin_N PF02736.14 KFM11117.1 - 1.5e-13 50.1 7.5 3.6e-13 48.9 5.2 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Filament PF00038.16 KFM11117.1 - 1.4e-08 34.5 231.2 4.6e-06 26.3 26.0 9.2 1 1 6 7 7 7 5 Intermediate filament protein Reo_sigmaC PF04582.7 KFM11117.1 - 4e-07 29.5 81.0 0.00073 18.8 3.6 10.2 1 1 8 11 11 11 10 Reovirus sigma C capsid protein DUF869 PF05911.6 KFM11117.1 - 4.7e-05 21.8 10.6 4.7e-05 21.8 7.4 7.1 1 1 5 6 6 6 2 Plant protein of unknown function (DUF869) IncA PF04156.9 KFM11117.1 - 0.00034 20.2 259.4 0.062 12.8 14.3 11.9 1 1 10 12 12 12 7 IncA protein TMF_DNA_bd PF12329.3 KFM11117.1 - 0.0047 16.6 21.6 0.0047 16.6 15.0 18.5 6 4 12 20 20 20 5 TATA element modulatory factor 1 DNA binding IQ PF00612.22 KFM11117.1 - 0.0058 16.1 1.3 0.069 12.8 0.2 2.9 2 0 0 2 2 2 1 IQ calmodulin-binding motif AAA_22 PF13401.1 KFM11117.1 - 0.093 12.8 0.0 0.093 12.8 0.0 6.0 4 3 1 6 6 6 0 AAA domain GSH_synth_ATP PF03917.12 KFM11120.1 - 5.4e-136 453.0 0.0 6.4e-136 452.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 KFM11120.1 - 1.3e-35 121.6 0.6 2.7e-35 120.6 0.4 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase AMP-binding PF00501.23 KFM11121.1 - 8.1e-93 311.0 0.0 9.6e-93 310.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFM11121.1 - 1e-20 74.4 0.0 2e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Y_phosphatase PF00102.22 KFM11123.1 - 6.5e-152 503.4 1.7 3.3e-84 281.8 0.0 2.4 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.16 KFM11123.1 - 8.5e-29 99.5 2.4 4.5e-11 42.7 0.0 5.7 4 1 1 5 5 5 3 Fibronectin type III domain MAM PF00629.18 KFM11123.1 - 6e-28 97.6 0.0 1.4e-27 96.4 0.0 1.7 1 0 0 1 1 1 1 MAM domain DSPc PF00782.15 KFM11123.1 - 3.2e-09 36.4 0.1 0.0011 18.4 0.0 2.5 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFM11123.1 - 1.4e-05 25.3 0.1 0.016 15.4 0.0 2.6 2 0 0 2 2 2 2 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KFM11123.1 - 6.8e-05 22.9 0.0 0.44 10.5 0.0 2.6 2 0 0 2 2 2 2 Inositol hexakisphosphate Ig_2 PF13895.1 KFM11123.1 - 0.00096 19.2 0.1 0.0035 17.4 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 KFM11123.1 - 0.036 13.9 0.0 0.081 12.7 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin I-set domain DctM PF06808.7 KFM11123.1 - 0.2 10.1 0.1 0.3 9.5 0.0 1.1 1 0 0 1 1 1 0 DctM-like transporters 7tm_1 PF00001.16 KFM11124.1 - 9.3e-29 100.3 5.9 9.3e-29 100.3 4.1 2.0 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 KFM11124.1 - 2.4e-23 82.5 3.5 2.4e-23 82.5 2.4 2.5 2 1 1 3 3 3 1 Olfactory receptor 7TM_GPCR_Srv PF10323.4 KFM11124.1 - 2.6e-05 23.5 5.0 2.6e-05 23.5 3.5 1.3 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.4 KFM11124.1 - 0.0004 19.6 5.5 0.00049 19.3 3.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Ribosomal_S4e PF00900.15 KFM11125.1 - 5.2e-33 112.5 0.5 8.3e-33 111.8 0.4 1.3 1 0 0 1 1 1 1 Ribosomal family S4e S4 PF01479.20 KFM11125.1 - 1.2e-05 24.6 0.0 2.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 KFM11125.1 - 2.8e-05 23.6 3.0 3.6e-05 23.3 0.1 2.7 3 1 0 3 3 3 1 KOW motif RS4NT PF08071.7 KFM11125.1 - 0.0055 16.5 0.6 0.013 15.2 0.4 1.7 1 0 0 1 1 1 1 RS4NT (NUC023) domain Hist_deacetyl PF00850.14 KFM11126.1 - 5.5e-78 262.4 0.0 6.6e-78 262.1 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Glyco_hydro_15 PF00723.16 KFM11127.1 - 2.3e-173 576.8 0.0 3.1e-173 576.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 TGF_beta PF00019.15 KFM11128.1 - 2e-28 98.7 0.1 3.2e-28 98.0 0.1 1.3 1 0 0 1 1 1 1 Transforming growth factor beta like domain PDZ_assoc PF10600.4 KFM11128.1 - 0.16 12.2 1.4 0.21 11.9 0.1 1.8 2 0 0 2 2 2 0 PDZ-associated domain of NMDA receptors ASD2 PF08687.6 KFM11130.1 - 1e-55 188.9 6.5 1.1e-55 188.7 4.5 1.0 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 DAGK_acc PF00609.14 KFM11131.1 - 1.6e-52 177.8 0.0 3.1e-52 176.9 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 KFM11131.1 - 1.6e-28 98.7 0.0 2.7e-27 94.7 0.0 2.6 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.17 KFM11131.1 - 2.5e-18 65.5 24.5 9.1e-10 38.1 3.6 2.7 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.24 KFM11131.1 - 3.2e-17 62.6 0.7 7.4e-17 61.4 0.5 1.7 1 0 0 1 1 1 1 PH domain SAM_2 PF07647.12 KFM11131.1 - 1.5e-07 31.1 0.0 3.3e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.1 KFM11131.1 - 3.3e-07 30.5 1.6 1.2e-05 25.5 1.1 2.8 1 1 0 1 1 1 1 Pleckstrin homology domain SAM_1 PF00536.25 KFM11131.1 - 4.9e-07 29.8 0.0 1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_8 PF15409.1 KFM11131.1 - 5.1e-05 23.2 0.2 0.00013 21.9 0.2 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Myosin_head PF00063.16 KFM11131.1 - 0.0012 17.0 0.0 0.0021 16.1 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) C1_3 PF07649.7 KFM11131.1 - 0.013 15.4 2.3 0.013 15.4 1.6 2.6 2 0 0 2 2 2 0 C1-like domain Mcp5_PH PF12814.2 KFM11131.1 - 0.041 13.8 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology Cyclin_N PF00134.18 KFM11132.1 - 1.8e-06 27.5 0.0 3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Gal_Lectin PF02140.13 KFM11133.1 - 5.3e-36 122.7 5.4 1e-17 64.2 0.3 2.3 2 0 0 2 2 2 2 Galactose binding lectin domain FAM176 PF14851.1 KFM11133.1 - 2e-10 40.5 0.0 3.3e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 FAM176 family DUF3395 PF11875.3 KFM11133.1 - 0.062 12.9 0.1 15 5.2 0.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3395) Dickkopf_N PF04706.7 KFM11133.1 - 1.4 9.1 6.7 4.5 7.5 0.6 2.6 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region GST_N_3 PF13417.1 KFM11134.1 - 3.6e-07 30.3 0.0 6.3e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFM11134.1 - 3.3e-06 26.8 0.0 6.4e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KFM11134.1 - 3.3e-06 26.9 0.0 7.5e-06 25.8 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 KFM11134.1 - 0.00075 19.4 0.0 0.0028 17.6 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin DUF1533 PF07550.6 KFM11134.1 - 0.025 14.5 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1533) GST_C_3 PF14497.1 KFM11134.1 - 0.032 14.6 0.0 0.053 14.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KFM11134.1 - 0.058 13.3 0.0 0.18 11.7 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Amidase PF01425.16 KFM11136.1 - 4e-89 299.4 0.0 5.4e-89 299.0 0.0 1.2 1 0 0 1 1 1 1 Amidase TSC22 PF01166.13 KFM11137.1 - 2.6e-30 104.1 5.8 2.6e-30 104.1 4.1 2.0 2 0 0 2 2 2 1 TSC-22/dip/bun family DUF972 PF06156.8 KFM11137.1 - 0.0011 19.2 1.4 0.0011 19.2 0.9 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF972) DivIC PF04977.10 KFM11137.1 - 0.0013 18.1 3.6 0.0057 16.1 1.7 2.2 2 0 0 2 2 2 1 Septum formation initiator DUF904 PF06005.7 KFM11137.1 - 0.0018 18.5 5.6 0.0018 18.5 3.9 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF904) MAD PF05557.8 KFM11137.1 - 0.0032 15.6 2.7 0.012 13.7 2.2 1.6 2 0 0 2 2 2 1 Mitotic checkpoint protein DUF16 PF01519.11 KFM11137.1 - 0.022 14.9 1.1 0.039 14.1 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF948 PF06103.6 KFM11137.1 - 0.072 12.9 0.3 0.14 12.0 0.2 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) bZIP_2 PF07716.10 KFM11137.1 - 0.087 12.6 5.2 0.19 11.5 3.6 1.5 1 0 0 1 1 1 0 Basic region leucine zipper Fzo_mitofusin PF04799.8 KFM11137.1 - 0.1 12.0 0.9 0.2 11.0 0.6 1.4 1 0 0 1 1 1 0 fzo-like conserved region bZIP_1 PF00170.16 KFM11137.1 - 0.77 9.7 5.3 1.8 8.5 3.6 1.6 1 0 0 1 1 1 0 bZIP transcription factor IncA PF04156.9 KFM11137.1 - 3.5 7.1 7.8 3.7 7.0 4.7 1.4 1 1 0 1 1 1 0 IncA protein SPRY PF00622.23 KFM11138.1 - 4.6e-16 59.0 0.1 8.2e-16 58.2 0.1 1.4 1 0 0 1 1 1 1 SPRY domain zf-B_box PF00643.19 KFM11138.1 - 4.6e-09 36.0 12.3 2.2e-08 33.8 0.6 4.6 6 0 0 6 6 6 2 B-box zinc finger zf-C3HC4_3 PF13920.1 KFM11138.1 - 6.9e-08 32.0 7.0 6.9e-08 32.0 4.8 3.7 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM11138.1 - 3.7e-07 30.0 11.4 3.7e-07 30.0 7.9 3.8 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) fn3 PF00041.16 KFM11138.1 - 5.4e-07 29.6 0.2 1e-06 28.7 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III domain zf-C3HC4_4 PF15227.1 KFM11138.1 - 1.1e-06 28.4 12.8 1.1e-06 28.4 8.9 3.9 5 0 0 5 5 5 2 zinc finger of C3HC4-type, RING PRY PF13765.1 KFM11138.1 - 1.8e-06 27.3 0.0 8.5e-06 25.2 0.0 2.2 2 0 0 2 2 2 1 SPRY-associated domain zf-C3HC4 PF00097.20 KFM11138.1 - 2.5e-06 27.0 10.8 2.5e-06 27.0 7.5 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM11138.1 - 2.9e-06 26.9 10.9 2.9e-06 26.9 7.6 3.0 2 1 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 KFM11138.1 - 0.00013 21.5 7.6 0.00052 19.6 5.3 2.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 KFM11138.1 - 0.00014 21.4 8.9 0.00014 21.4 6.2 3.7 4 0 0 4 4 4 1 zinc-RING finger domain DNA_topoisoIV PF00521.15 KFM11138.1 - 0.85 8.3 8.8 1.2 7.8 6.1 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A zf-H2C2_2 PF13465.1 KFM11138.1 - 5.5 7.4 7.7 36 4.8 0.0 4.6 4 0 0 4 4 4 0 Zinc-finger double domain Fzo_mitofusin PF04799.8 KFM11138.1 - 6.6 6.0 9.6 0.89 8.9 2.9 2.1 1 1 1 2 2 2 0 fzo-like conserved region SNF2_N PF00176.18 KFM11139.1 - 1.1e-59 201.7 0.0 2.7e-59 200.4 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFM11139.1 - 3e-16 59.0 0.4 6.5e-14 51.5 0.1 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 KFM11139.1 - 7.1e-11 42.2 0.0 1.7e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KFM11139.1 - 1.3e-06 28.0 0.0 3.6e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 KFM11139.1 - 4e-06 25.8 0.0 7.2e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD_2 PF06733.10 KFM11139.1 - 0.013 14.9 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 Exo_endo_phos PF03372.18 KFM11140.1 - 9.6e-32 110.8 0.0 1.6e-31 110.1 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.22 KFM11140.1 - 2.2e-25 89.0 0.2 3.8e-25 88.2 0.2 1.4 1 0 0 1 1 1 1 RhoGAP domain Sigma70_r1_1 PF03979.9 KFM11140.1 - 0.08 12.8 0.1 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 Creatinase_N PF01321.13 KFM11141.1 - 0.00014 22.3 0.0 0.00017 22.0 0.0 1.1 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain DUF218 PF02698.12 KFM11141.1 - 0.027 13.9 0.0 0.028 13.9 0.0 1.1 1 0 0 1 1 1 0 DUF218 domain CLN3 PF02487.12 KFM11141.1 - 0.089 11.5 0.0 0.1 11.3 0.0 1.0 1 0 0 1 1 1 0 CLN3 protein Peptidase_M24 PF00557.19 KFM11142.1 - 1.1e-24 87.1 0.0 1.2e-24 87.0 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 SLY PF12485.3 KFM11143.1 - 6.8e-19 68.6 4.6 1.6e-18 67.4 3.2 1.6 1 0 0 1 1 1 1 Lymphocyte signaling adaptor protein SAM_2 PF07647.12 KFM11143.1 - 1.3e-09 37.7 0.6 1.9e-09 37.2 0.4 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFM11143.1 - 8.1e-09 35.5 0.2 1.2e-08 34.9 0.1 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.12 KFM11143.1 - 3.7e-05 23.1 0.0 6.8e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM11143.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 SH3 domain Ank_2 PF12796.2 KFM11144.1 - 1.1e-17 64.1 1.0 1.8e-11 44.1 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFM11144.1 - 1.4e-15 56.2 1.9 7.5e-07 28.6 0.3 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 KFM11144.1 - 9.1e-15 53.3 0.5 5.5e-06 26.1 0.2 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KFM11144.1 - 1.9e-12 47.3 4.0 3.2e-08 33.8 0.3 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM11144.1 - 7.6e-12 45.0 3.4 0.0001 22.4 0.3 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) I-set PF07679.11 KFM11145.1 - 1.1e-12 47.5 0.0 3.4e-08 33.2 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM11145.1 - 4.5e-09 36.3 0.0 0.0025 17.8 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.12 KFM11145.1 - 2.7e-07 30.4 0.9 6.3e-05 22.8 0.0 2.8 1 1 1 2 2 2 2 Immunoglobulin V-set domain ig PF00047.20 KFM11145.1 - 5.5e-06 26.4 0.6 0.013 15.5 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin domain V-set_CD47 PF08204.6 KFM11145.1 - 1.1e-05 25.1 1.5 0.0019 17.9 0.4 2.5 2 1 0 2 2 2 2 CD47 immunoglobulin-like domain Ig_3 PF13927.1 KFM11145.1 - 0.00023 21.6 0.2 0.17 12.4 0.0 2.7 2 1 0 2 2 2 2 Immunoglobulin domain Herpes_gE PF02480.11 KFM11145.1 - 0.012 13.9 0.0 0.041 12.1 0.0 1.8 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E Chordopox_A13L PF05961.6 KFM11145.1 - 0.027 14.4 0.1 0.068 13.1 0.0 1.7 1 0 0 1 1 1 0 Chordopoxvirus A13L protein PARP PF00644.15 KFM11146.1 - 5.4e-14 52.0 0.5 1.3e-13 50.9 0.4 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain zf-C3Hc3H PF13891.1 KFM11147.1 - 3.6e-17 62.1 7.6 5.3e-17 61.6 5.2 1.2 1 0 0 1 1 1 1 Potential DNA-binding domain zf-C3Hc3H PF13891.1 KFM11148.1 - 1e-16 60.6 5.4 2.2e-16 59.6 3.8 1.5 1 0 0 1 1 1 1 Potential DNA-binding domain zf-TRM13_CCCH PF11722.3 KFM11148.1 - 0.16 11.3 13.1 0.25 10.7 0.1 3.5 3 1 0 3 3 3 0 CCCH zinc finger in TRM13 protein NYD-SP28_assoc PF14775.1 KFM11149.1 - 2.5e-05 23.8 3.9 3.9e-05 23.2 2.7 1.3 1 0 0 1 1 1 1 Sperm tail C-terminal domain Peptidase_M16 PF00675.15 KFM11149.1 - 0.069 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) FKBP_C PF00254.23 KFM11150.1 - 0.021 14.8 0.0 0.36 10.8 0.0 2.1 1 1 1 2 2 2 0 FKBP-type peptidyl-prolyl cis-trans isomerase Arf PF00025.16 KFM11151.1 - 6.1e-79 263.3 0.1 7.3e-79 263.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KFM11151.1 - 5.4e-15 55.0 0.0 6.7e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 KFM11151.1 - 2.8e-13 49.5 0.0 3.1e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KFM11151.1 - 1.6e-11 43.7 0.0 2e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KFM11151.1 - 4.8e-11 41.9 1.5 5.8e-08 31.8 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 KFM11151.1 - 2.5e-09 37.6 0.0 3.7e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KFM11151.1 - 3.3e-06 27.0 0.0 4.5e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFM11151.1 - 0.0011 18.4 0.1 0.0088 15.4 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 KFM11151.1 - 0.0059 15.7 0.9 0.019 14.0 0.6 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 KFM11151.1 - 0.067 13.0 0.2 0.14 12.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain F5_F8_type_C PF00754.20 KFM11152.1 - 8e-53 177.6 1.7 1.3e-26 92.9 0.7 2.3 2 0 0 2 2 2 2 F5/8 type C domain CUB PF00431.15 KFM11152.1 - 1.9e-43 147.0 0.0 8.7e-30 103.0 0.0 2.5 2 0 0 2 2 2 2 CUB domain MAM PF00629.18 KFM11152.1 - 2.1e-25 89.3 0.1 6.9e-25 87.6 0.0 1.9 2 0 0 2 2 2 1 MAM domain DUF3481 PF11980.3 KFM11152.1 - 1.9e-24 85.3 0.1 3.7e-24 84.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3481) zf-C3Hc3H PF13891.1 KFM11153.1 - 1e-20 73.5 5.2 3.2e-20 71.9 3.6 1.8 1 0 0 1 1 1 1 Potential DNA-binding domain zf-primase PF09329.6 KFM11153.1 - 0.067 12.8 0.1 0.067 12.8 0.1 2.2 2 0 0 2 2 2 0 Primase zinc finger Molybdopterin PF00384.17 KFM11154.1 - 1.2e-75 254.9 0.0 1.5e-74 251.3 0.0 2.0 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.4 KFM11154.1 - 9.6e-19 66.3 0.1 2.4e-18 65.0 0.1 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.1 KFM11154.1 - 1.7e-17 62.9 0.1 4.4e-17 61.6 0.0 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF1982 PF09326.6 KFM11154.1 - 6e-16 58.3 0.0 1.3e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 KFM11154.1 - 1.1e-09 37.9 0.4 1.1e-09 37.9 0.3 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 KFM11154.1 - 0.047 13.4 0.7 7.1 6.3 0.1 2.5 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain EF1_GNE PF00736.14 KFM11155.1 - 1.6e-35 120.6 0.5 2.6e-35 119.9 0.4 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 KFM11155.1 - 1e-13 51.1 9.6 3.9e-13 49.2 6.7 2.1 1 0 0 1 1 1 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 KFM11155.1 - 0.008 16.6 0.1 0.022 15.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFM11155.1 - 0.065 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain 7tm_1 PF00001.16 KFM11156.1 - 1.2e-48 165.4 23.1 1.6e-48 165.0 16.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.4 KFM11156.1 - 0.00016 20.9 4.5 0.00016 20.9 3.1 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF788 PF05620.6 KFM11156.1 - 1.5 8.6 6.7 4.5 7.1 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF788) zf-DBF PF07535.7 KFM11157.1 - 2.5e-08 33.4 7.2 6.4e-08 32.1 5.0 1.7 1 0 0 1 1 1 1 DBF zinc finger Reprolysin PF01421.14 KFM11158.1 - 7.8e-59 198.6 0.0 1.7e-58 197.4 0.0 1.6 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.14 KFM11158.1 - 2.9e-28 98.2 0.2 5.6e-28 97.3 0.1 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_CR PF08516.7 KFM11158.1 - 3e-25 88.5 5.8 3e-25 88.5 4.0 3.7 4 1 0 4 4 4 1 ADAM cysteine-rich Disintegrin PF00200.18 KFM11158.1 - 1.6e-16 60.2 23.9 1.6e-16 60.2 16.6 4.1 3 1 1 4 4 4 1 Disintegrin Reprolysin_5 PF13688.1 KFM11158.1 - 3e-08 33.8 0.4 1.5e-07 31.5 0.3 2.3 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KFM11158.1 - 5.7e-08 33.3 0.5 1.4e-07 32.0 0.0 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFM11158.1 - 6.9e-06 26.2 1.6 0.0005 20.1 0.1 3.2 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFM11158.1 - 0.00026 20.5 0.5 0.0011 18.5 0.3 2.0 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like EGF_2 PF07974.8 KFM11158.1 - 0.00054 20.0 11.0 0.00054 20.0 7.6 6.4 4 2 2 6 6 6 1 EGF-like domain EF-hand_3 PF09069.6 KFM11161.1 - 1.6e-18 66.5 0.0 2.3e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 EF-hand EF-hand_2 PF09068.6 KFM11161.1 - 0.0017 18.3 0.0 0.0028 17.7 0.0 1.4 1 0 0 1 1 1 1 EF hand Ldh_1_C PF02866.13 KFM11162.1 - 2.7e-09 36.9 0.1 5.8e-06 26.1 0.0 2.6 3 0 0 3 3 3 2 lactate/malate dehydrogenase, alpha/beta C-terminal domain DUF2424 PF10340.4 KFM11162.1 - 0.041 12.5 0.3 0.064 11.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) MRP-S24 PF14955.1 KFM11162.1 - 0.048 13.5 0.0 0.086 12.6 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S24 FAST_1 PF06743.10 KFM11163.1 - 4.7e-16 58.2 6.9 2.6e-14 52.6 0.2 4.7 3 3 3 6 6 6 1 FAST kinase-like protein, subdomain 1 FAST_2 PF08368.7 KFM11163.1 - 1.2e-12 48.0 0.0 4.2e-12 46.2 0.0 2.0 1 0 0 1 1 1 1 FAST kinase-like protein, subdomain 2 RAP PF08373.5 KFM11163.1 - 6.1e-08 32.3 0.0 1.3e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 RAP domain Fanconi_A PF03511.9 KFM11163.1 - 0.017 14.8 0.2 1.4 8.7 0.1 2.9 2 0 0 2 2 2 0 Fanconi anaemia group A protein zf-H2C2_2 PF13465.1 KFM11164.1 - 1.6e-10 40.7 21.1 9.8e-06 25.6 0.4 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFM11164.1 - 4.8e-07 29.7 22.7 0.00041 20.5 0.4 3.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM11164.1 - 3.4e-05 23.8 19.4 0.0037 17.5 0.9 4.0 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KFM11164.1 - 0.24 11.6 0.1 0.24 11.6 0.0 3.9 4 1 0 4 4 4 0 C2H2-type zinc-finger domain pKID PF02173.12 KFM11165.1 - 1.8e-21 75.0 2.7 4.3e-21 73.8 1.8 1.6 1 0 0 1 1 1 1 pKID domain bZIP_1 PF00170.16 KFM11165.1 - 2.2e-16 59.5 7.6 2.2e-16 59.5 5.3 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KFM11165.1 - 0.00018 21.2 4.1 0.00018 21.2 2.8 2.0 2 0 0 2 2 2 1 Basic region leucine zipper Methyltransf_16 PF10294.4 KFM11166.1 - 2.9e-36 124.5 0.0 3.4e-36 124.3 0.0 1.0 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 KFM11166.1 - 2.5e-05 23.5 0.0 3.1e-05 23.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 KFM11166.1 - 3.7e-05 23.1 0.0 5.1e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 KFM11166.1 - 5.8e-05 22.8 0.0 7e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFM11166.1 - 0.00011 22.7 0.0 0.00022 21.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFM11166.1 - 0.0062 16.5 0.1 0.0089 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFM11166.1 - 0.0092 15.5 0.0 0.012 15.1 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Cyclin_N PF00134.18 KFM11167.1 - 1.9e-15 56.5 0.3 3.3e-15 55.7 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 KFM11167.1 - 4.6e-12 46.5 0.5 6.6e-12 46.0 0.1 1.5 2 0 0 2 2 2 1 Cyclin Frizzled PF01534.12 KFM11168.1 - 1.1e-146 487.8 11.8 1.3e-146 487.5 8.2 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.17 KFM11168.1 - 8e-34 116.4 1.4 1.8e-33 115.3 1.0 1.6 1 0 0 1 1 1 1 Fz domain 7tm_1 PF00001.16 KFM11168.1 - 0.38 9.8 11.3 0.02 14.0 3.3 2.2 2 1 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) DUF4206 PF13901.1 KFM11169.1 - 1e-74 250.4 10.1 2.4e-74 249.2 7.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4206) PH PF00169.24 KFM11169.1 - 9.7e-14 51.4 0.1 1.6e-09 37.8 0.0 2.7 2 0 0 2 2 2 2 PH domain ALS2CR8 PF15299.1 KFM11170.1 - 2e-62 210.7 1.4 2.9e-62 210.2 1.0 1.2 1 0 0 1 1 1 1 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 WD40 PF00400.27 KFM11171.1 - 1.7e-53 176.6 31.8 1.1e-10 40.8 0.9 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat NLE PF08154.7 KFM11171.1 - 6.6e-14 51.6 0.0 1.2e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain FAM117 PF15388.1 KFM11172.1 - 6.5e-121 403.4 12.7 8.4e-121 403.0 8.8 1.1 1 0 0 1 1 1 1 Protein Family FAM117 Pkinase PF00069.20 KFM11173.1 - 3.9e-47 160.5 0.0 6.5e-47 159.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM11173.1 - 6e-30 104.1 0.0 1.3e-29 103.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Activin_recp PF01064.18 KFM11173.1 - 4.2e-12 46.5 9.0 4.2e-12 46.5 6.2 2.0 2 0 0 2 2 2 1 Activin types I and II receptor domain APH PF01636.18 KFM11173.1 - 0.00043 20.1 0.0 0.0013 18.5 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Nop PF01798.13 KFM11174.1 - 3.3e-59 198.4 0.6 3.3e-59 198.4 0.4 1.9 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 KFM11174.1 - 1.8e-28 98.1 0.0 3.5e-28 97.1 0.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KFM11174.1 - 2e-13 50.2 1.9 2e-13 50.2 1.3 2.5 2 0 0 2 2 2 1 NOP5NT (NUC127) domain Rad60-SLD PF11976.3 KFM11175.1 - 5e-23 80.5 0.2 6.1e-23 80.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KFM11175.1 - 2.1e-17 62.2 0.6 2.6e-17 61.9 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin family Frizzled PF01534.12 KFM11176.1 - 2.7e-146 486.5 19.6 3.3e-146 486.2 13.6 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.17 KFM11176.1 - 4.9e-35 120.3 4.2 8.7e-35 119.5 2.9 1.4 1 0 0 1 1 1 1 Fz domain Ndc1_Nup PF09531.5 KFM11176.1 - 0.2 10.0 1.9 0.38 9.1 1.3 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-DHHC PF01529.15 KFM11176.1 - 7 6.0 10.1 0.5 9.7 0.1 3.0 2 1 1 3 3 3 0 DHHC palmitoyltransferase RCC1 PF00415.13 KFM11177.1 - 1.3e-42 143.7 17.3 3e-12 46.5 0.1 7.1 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KFM11177.1 - 1.5e-26 91.3 30.5 1.9e-07 30.4 1.1 7.9 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat MORN PF02493.15 KFM11177.1 - 2.1e-24 83.7 31.3 2.5e-05 23.7 1.9 9.4 8 1 0 8 8 8 6 MORN repeat VPS9 PF02204.13 KFM11177.1 - 6.8e-23 80.6 0.1 4.3e-22 78.1 0.1 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain RhoGEF PF00621.15 KFM11177.1 - 3.1e-06 27.1 1.3 7.4e-06 25.9 0.9 1.7 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 KFM11177.1 - 0.0075 16.4 0.1 0.024 14.8 0.0 1.9 2 0 0 2 2 2 1 PH domain YoaP PF14268.1 KFM11177.1 - 0.14 11.3 0.1 0.37 10.0 0.0 1.6 1 0 0 1 1 1 0 YoaP-like TMEM237 PF15383.1 KFM11178.1 - 1.8e-96 322.1 0.2 2.9e-96 321.5 0.1 1.3 1 0 0 1 1 1 1 Transmembrane protein 237 DUF4516 PF14990.1 KFM11178.1 - 0.061 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4516) HAP1_N PF04849.8 KFM11179.1 - 2.6e-113 378.0 35.3 3.7e-113 377.5 24.4 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Milton PF12448.3 KFM11179.1 - 2.4e-56 190.3 18.8 8.4e-37 126.8 3.2 3.1 3 0 0 3 3 3 2 Kinesin associated protein TMF_TATA_bd PF12325.3 KFM11179.1 - 0.011 15.4 16.2 0.011 15.4 11.3 3.8 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF4279 PF14106.1 KFM11179.1 - 0.32 10.8 3.7 1.8 8.4 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) AATF-Che1 PF13339.1 KFM11179.1 - 1.7 8.8 18.7 3.6 7.7 5.1 3.0 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor DUF972 PF06156.8 KFM11179.1 - 2.1 8.7 26.2 4.8 7.5 2.9 4.2 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DUF948 PF06103.6 KFM11179.1 - 4.5 7.2 6.2 27 4.7 0.6 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DED PF01335.16 KFM11180.1 - 3.5e-39 132.8 12.9 4.1e-20 71.6 1.3 2.9 3 0 0 3 3 3 2 Death effector domain Peptidase_C14 PF00656.17 KFM11180.1 - 1.4e-33 116.6 0.1 1.9e-33 116.1 0.1 1.2 1 0 0 1 1 1 1 Caspase domain YtzH PF14165.1 KFM11180.1 - 0.064 13.4 0.0 11 6.2 0.0 2.6 2 0 0 2 2 2 0 YtzH-like protein Peptidase_C14 PF00656.17 KFM11181.1 - 1.1e-43 149.7 0.1 2.1e-43 148.8 0.0 1.5 2 0 0 2 2 2 1 Caspase domain DED PF01335.16 KFM11181.1 - 3.5e-34 116.7 15.4 5.9e-18 64.7 2.3 2.7 2 0 0 2 2 2 2 Death effector domain NDUF_B12 PF08122.7 KFM11182.1 - 1.2e-23 82.5 0.3 1.7e-23 82.0 0.2 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Hyccin PF09790.4 KFM11183.1 - 1.6e-122 408.1 0.1 2.1e-122 407.8 0.1 1.1 1 0 0 1 1 1 1 Hyccin ORC2 PF04084.9 KFM11184.1 - 1.7e-108 362.3 1.8 2.6e-108 361.7 1.3 1.3 1 0 0 1 1 1 1 Origin recognition complex subunit 2 NIF3 PF01784.13 KFM11185.1 - 1.3e-76 257.3 0.0 1.9e-76 256.8 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) DUF4503 PF14951.1 KFM11185.1 - 0.024 12.7 0.1 0.038 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) Pro_isomerase PF00160.16 KFM11186.1 - 4.1e-52 176.4 0.1 4.6e-52 176.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.20 KFM11187.1 - 4e-68 229.3 0.2 5.8e-68 228.8 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM11187.1 - 1.8e-25 89.4 0.2 2.7e-24 85.6 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase W2 PF02020.13 KFM11188.1 - 1.5e-22 79.3 13.0 4.1e-22 77.9 2.7 3.4 3 0 0 3 3 3 2 eIF4-gamma/eIF5/eIF2-epsilon Ald_Xan_dh_C2 PF02738.13 KFM11189.1 - 8.6e-195 648.1 0.0 1.1e-194 647.7 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 KFM11189.1 - 2.9e-45 153.7 0.0 6e-45 152.7 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.17 KFM11189.1 - 1e-34 118.8 1.8 2.4e-34 117.7 1.2 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.15 KFM11189.1 - 2.6e-29 100.9 1.0 6.4e-29 99.6 0.7 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.12 KFM11189.1 - 4.7e-26 90.7 0.1 2e-24 85.5 0.0 2.9 3 0 0 3 3 3 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.22 KFM11189.1 - 0.00016 21.3 1.9 0.00016 21.3 1.3 3.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain SAICAR_synt PF01259.13 KFM11189.1 - 0.16 11.0 0.1 0.66 9.0 0.0 1.9 2 0 0 2 2 2 0 SAICAR synthetase Shugoshin_C PF07557.6 KFM11190.1 - 3.3e-06 26.4 0.9 5.2e-06 25.8 0.7 1.3 1 0 0 1 1 1 1 Shugoshin C terminus GLTP PF08718.6 KFM11190.1 - 0.13 12.2 0.3 0.2 11.7 0.2 1.3 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) BTB_2 PF02214.17 KFM11191.1 - 5.5e-12 45.7 0.0 3.9e-11 43.0 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain DUF1387 PF07139.6 KFM11192.1 - 8.4e-106 353.9 19.5 8.4e-106 353.9 13.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1387) DUF2973 PF11189.3 KFM11193.1 - 0.0016 18.1 0.0 0.13 12.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2973) PRESAN PF09687.5 KFM11193.1 - 0.0071 16.3 2.3 0.05 13.6 0.0 2.2 1 1 0 1 1 1 1 Plasmodium RESA N-terminal LON PF02190.11 KFM11193.1 - 0.031 13.9 0.0 0.036 13.7 0.0 1.1 1 0 0 1 1 1 0 ATP-dependent protease La (LON) domain FKBP_N PF01346.13 KFM11193.1 - 0.22 11.5 2.3 3.7 7.6 1.4 2.2 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Cupin_8 PF13621.1 KFM11195.1 - 8.6e-45 153.1 0.1 1.2e-44 152.7 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KFM11195.1 - 2.5e-10 40.1 0.0 3.8e-10 39.5 0.0 1.5 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.17 KFM11195.1 - 0.0067 16.6 0.0 0.017 15.3 0.0 1.7 2 0 0 2 2 2 1 JmjC domain, hydroxylase DUF4269 PF14091.1 KFM11195.1 - 0.05 13.5 0.1 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) DUF1493 PF07377.7 KFM11195.1 - 0.11 12.5 0.6 0.26 11.3 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) UPF0565 PF10561.4 KFM11196.1 - 3e-83 279.2 0.3 3.4e-83 279.0 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0565 CUT PF02376.10 KFM11197.1 - 1.4e-52 175.4 8.3 3.8e-27 93.8 0.1 3.9 4 0 0 4 4 4 2 CUT domain Homeobox PF00046.24 KFM11197.1 - 2.7e-07 30.1 0.0 9.6e-07 28.3 0.0 2.0 1 0 0 1 1 1 1 Homeobox domain PI-PLC-X PF00388.14 KFM11198.1 - 9.6e-50 167.7 0.4 2.3e-49 166.5 0.0 1.9 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KFM11198.1 - 1e-44 151.2 0.2 2.4e-44 150.0 0.2 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 KFM11198.1 - 2.6e-24 85.0 0.1 7.3e-24 83.5 0.1 1.9 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 KFM11198.1 - 5.8e-18 64.5 0.0 1.4e-17 63.3 0.0 1.7 1 0 0 1 1 1 1 C2 domain Mcp5_PH PF12814.2 KFM11198.1 - 0.013 15.4 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.24 KFM11198.1 - 0.051 13.7 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 PH domain EF-hand_7 PF13499.1 KFM11198.1 - 0.075 13.1 0.5 10 6.3 0.0 3.0 2 0 0 2 2 2 0 EF-hand domain pair Raftlin PF15250.1 KFM11199.1 - 1.8e-198 659.7 0.0 2.1e-198 659.4 0.0 1.0 1 0 0 1 1 1 1 Raftlin Mob1_phocein PF03637.12 KFM11200.1 - 1.1e-60 204.3 1.4 1.3e-60 204.0 1.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family Cpn10 PF00166.16 KFM11201.1 - 1.8e-28 98.3 0.1 2e-28 98.1 0.1 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Cpn60_TCP1 PF00118.19 KFM11202.1 - 2.3e-118 395.8 12.4 2.7e-118 395.6 8.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1547 PF07577.6 KFM11202.1 - 0.061 12.9 2.3 0.68 9.6 0.2 3.0 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1547) Polyketide_cyc PF03364.15 KFM11203.1 - 7.7e-24 84.1 0.0 9.7e-24 83.8 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport SF3b1 PF08920.5 KFM11204.1 - 3.6e-42 143.8 30.5 6.9e-39 133.1 7.3 4.5 1 1 2 3 3 3 3 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 KFM11204.1 - 4e-12 46.2 2.8 0.0019 18.4 0.0 7.0 6 2 3 9 9 8 3 HEAT repeats HEAT PF02985.17 KFM11204.1 - 1e-09 37.6 6.4 0.33 11.1 0.0 9.4 10 0 0 10 10 9 1 HEAT repeat HEAT_EZ PF13513.1 KFM11204.1 - 7.1e-07 29.5 2.7 1.5 9.3 0.0 7.9 8 1 1 9 9 9 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KFM11204.1 - 8e-06 26.1 0.5 1.3 9.4 0.0 4.6 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region TIP120 PF08623.5 KFM11204.1 - 0.0012 18.4 0.2 0.11 12.1 0.0 2.8 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) CLASP_N PF12348.3 KFM11204.1 - 0.0026 17.1 0.8 3.3 6.9 0.0 3.2 3 0 0 3 3 3 2 CLASP N terminal Adaptin_N PF01602.15 KFM11204.1 - 0.013 13.8 2.4 0.27 9.4 1.7 2.9 1 1 0 1 1 1 0 Adaptin N terminal region Arm PF00514.18 KFM11204.1 - 0.027 14.2 1.4 10 6.1 0.0 4.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF4047 PF13256.1 KFM11204.1 - 0.053 13.4 0.1 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) UME PF08064.8 KFM11204.1 - 0.11 12.4 0.0 2.6 8.0 0.0 3.4 3 1 1 4 4 4 0 UME (NUC010) domain Ank_2 PF12796.2 KFM11206.1 - 3.2e-199 645.9 62.8 2.5e-24 85.4 0.3 13.8 2 2 10 13 13 13 13 Ankyrin repeats (3 copies) Ank PF00023.25 KFM11206.1 - 2.1e-197 629.9 76.0 5.6e-10 38.5 0.5 28.2 28 0 0 28 28 28 27 Ankyrin repeat Ank_4 PF13637.1 KFM11206.1 - 6.7e-163 526.5 54.8 4.1e-15 55.8 0.2 21.6 6 5 17 23 23 23 23 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM11206.1 - 2.3e-138 447.0 72.2 7.2e-10 38.7 0.4 23.8 5 5 18 24 24 24 23 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM11206.1 - 1.4e-126 399.4 63.3 3.5e-08 32.9 0.1 27.9 28 0 0 28 28 28 24 Ankyrin repeat Ribosomal_S6 PF01250.12 KFM11206.1 - 0.05 13.4 0.0 3.9 7.3 0.0 3.5 3 1 1 4 4 4 0 Ribosomal protein S6 PGAP1 PF07819.8 KFM11207.1 - 9.7e-75 251.0 0.0 1.5e-74 250.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KFM11207.1 - 0.00034 20.5 0.0 0.00053 19.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFM11207.1 - 0.00044 20.0 0.0 0.00094 18.9 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KFM11207.1 - 0.0039 16.5 0.0 0.0075 15.5 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 KFM11207.1 - 0.024 14.2 0.0 0.063 12.8 0.0 1.7 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_1 PF00561.15 KFM11207.1 - 0.066 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFM11207.1 - 0.074 12.2 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family HECT PF00632.20 KFM11209.1 - 3.6e-93 312.1 0.0 5.9e-93 311.4 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 KFM11209.1 - 3.1e-17 62.1 0.3 3.5e-09 36.3 0.2 2.5 2 0 0 2 2 2 2 WW domain C2 PF00168.25 KFM11209.1 - 7.3e-10 38.5 0.0 1.4e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain Pkinase PF00069.20 KFM11210.1 - 6.4e-64 215.5 0.0 8e-64 215.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM11210.1 - 3.3e-36 124.6 0.0 4.1e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM11210.1 - 0.0044 16.0 0.0 0.0068 15.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFM11210.1 - 0.06 13.0 0.1 0.19 11.4 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Dynein_heavy PF03028.10 KFM11211.1 - 2.1e-248 826.0 0.0 3.6e-248 825.2 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 KFM11211.1 - 4.3e-134 447.0 6.4 4.3e-134 447.0 4.5 3.2 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 KFM11211.1 - 2.3e-93 311.9 0.1 7.7e-93 310.2 0.1 2.0 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 KFM11211.1 - 1.1e-72 244.1 0.2 1.9e-71 240.2 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 KFM11211.1 - 2e-62 210.0 0.1 8.5e-62 207.9 0.1 2.1 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 MT PF12777.2 KFM11211.1 - 9.6e-55 185.7 5.7 9.6e-55 185.7 4.0 2.2 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.2 KFM11211.1 - 7.3e-52 176.1 0.0 1.8e-51 174.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 AAA_5 PF07728.9 KFM11211.1 - 7.7e-19 67.8 0.0 0.0014 18.3 0.0 6.2 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA PF00004.24 KFM11211.1 - 4.1e-07 30.2 2.0 1.1 9.4 0.0 5.7 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFM11211.1 - 4.8e-06 26.7 0.9 0.53 10.4 0.0 5.0 5 0 0 5 5 4 1 AAA domain AAA_16 PF13191.1 KFM11211.1 - 7.8e-05 22.7 0.0 2.6 7.9 0.0 4.3 4 1 0 4 4 3 1 AAA ATPase domain AAA_19 PF13245.1 KFM11211.1 - 0.0012 18.5 0.1 1.6 8.5 0.0 3.1 3 0 0 3 3 2 1 Part of AAA domain RNA_helicase PF00910.17 KFM11211.1 - 0.0017 18.4 0.2 6.5 6.9 0.0 3.7 3 0 0 3 3 2 0 RNA helicase AAA_17 PF13207.1 KFM11211.1 - 0.0036 18.1 2.9 0.59 10.9 0.0 4.0 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.1 KFM11211.1 - 0.0088 16.3 3.4 0.76 10.0 0.0 5.0 5 0 0 5 5 3 1 AAA domain EF-hand_1 PF00036.27 KFM11211.1 - 0.013 14.7 2.1 0.064 12.5 1.4 2.3 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.1 KFM11211.1 - 0.048 13.2 1.6 0.19 11.3 1.1 2.1 1 0 0 1 1 1 0 EF-hand domain pair AAA_33 PF13671.1 KFM11211.1 - 0.048 13.5 0.0 1.4 8.8 0.0 3.1 3 0 0 3 3 2 0 AAA domain DUF258 PF03193.11 KFM11211.1 - 0.057 12.6 0.0 0.23 10.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 KFM11211.1 - 0.062 12.7 0.1 5.3 6.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain EF-hand_6 PF13405.1 KFM11211.1 - 0.076 12.9 2.3 0.36 10.8 1.6 2.2 1 0 0 1 1 1 0 EF-hand domain HrpB7 PF09486.5 KFM11211.1 - 1 9.2 14.4 6.7 6.6 4.6 2.8 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DivIC PF04977.10 KFM11211.1 - 9.7 5.7 12.6 1.2 8.7 3.7 3.0 2 0 0 2 2 2 0 Septum formation initiator BIR PF00653.16 KFM11212.1 - 3.2e-20 72.3 3.1 5.7e-20 71.5 2.2 1.4 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain zf-C3HC PF07967.8 KFM11212.1 - 0.0026 17.5 1.5 0.003 17.3 1.0 1.4 1 1 0 1 1 1 1 C3HC zinc finger-like Zip PF02535.17 KFM11213.1 - 8.4e-101 337.1 16.7 8.4e-101 337.1 11.5 4.9 2 2 1 3 3 3 1 ZIP Zinc transporter Connexin PF00029.14 KFM11215.1 - 1.8e-49 166.2 0.2 2.7e-49 165.6 0.1 1.2 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 KFM11215.1 - 3.6e-24 84.3 0.2 9e-24 83.0 0.1 1.7 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain DUF4618 PF15397.1 KFM11215.1 - 0.0065 15.8 0.4 0.0088 15.4 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) CemA PF03040.9 KFM11215.1 - 6.9 6.2 7.2 9.1 5.8 0.0 2.7 2 1 1 3 3 3 0 CemA family TSC22 PF01166.13 KFM11216.1 - 0.006 16.5 1.8 0.0083 16.0 1.2 1.3 1 0 0 1 1 1 1 TSC-22/dip/bun family DUF904 PF06005.7 KFM11216.1 - 0.011 15.9 2.2 0.017 15.3 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF3450 PF11932.3 KFM11216.1 - 0.043 13.0 0.0 0.043 13.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF972 PF06156.8 KFM11216.1 - 0.043 14.1 1.2 0.23 11.8 0.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DivIC PF04977.10 KFM11216.1 - 0.059 12.8 1.4 0.077 12.5 1.0 1.2 1 0 0 1 1 1 0 Septum formation initiator CENP-F_N PF10481.4 KFM11216.1 - 0.059 12.7 0.5 0.062 12.6 0.3 1.1 1 0 0 1 1 1 0 Cenp-F N-terminal domain HALZ PF02183.13 KFM11216.1 - 0.08 12.6 2.4 0.22 11.2 1.7 1.8 1 1 0 1 1 1 0 Homeobox associated leucine zipper AcylCoA_dehyd_C PF12186.3 KFM11216.1 - 0.092 12.6 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase C terminal Gtr1_RagA PF04670.7 KFM11217.1 - 3.5e-63 212.8 2.5 4.6e-63 212.4 1.8 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 KFM11217.1 - 0.019 14.1 0.1 0.028 13.6 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family Utp11 PF03998.8 KFM11218.1 - 3.2e-70 236.7 19.7 3.5e-70 236.5 13.7 1.0 1 0 0 1 1 1 1 Utp11 protein Aminotran_4 PF01063.14 KFM11218.1 - 0.092 12.1 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Aminotransferase class IV Takusan PF04822.8 KFM11218.1 - 0.29 10.9 4.7 2 8.2 0.1 2.8 3 0 0 3 3 3 0 Takusan MAP7 PF05672.6 KFM11218.1 - 2 7.7 10.3 0.66 9.3 0.6 2.3 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family LIM PF00412.17 KFM11219.1 - 2.8e-48 161.8 71.9 3.1e-12 46.3 4.2 5.1 5 0 0 5 5 5 5 LIM domain Ureidogly_hydro PF04115.7 KFM11219.1 - 0.04 13.2 0.0 0.83 8.9 0.0 2.6 1 1 2 3 3 3 0 Ureidoglycolate hydrolase TNFR_c6 PF00020.13 KFM11219.1 - 0.13 12.3 0.5 0.13 12.3 0.4 9.7 6 3 3 10 10 10 0 TNFR/NGFR cysteine-rich region DUF3449 PF11931.3 KFM11220.1 - 1.8e-75 252.8 5.7 1.8e-75 252.8 4.0 2.3 2 2 0 2 2 2 1 Domain of unknown function (DUF3449) Telomere_Sde2_2 PF13297.1 KFM11220.1 - 9.3e-29 98.4 1.4 2e-28 97.4 1.0 1.6 1 0 0 1 1 1 1 Telomere stability C-terminal SF3a60_bindingd PF12108.3 KFM11220.1 - 2.7e-15 55.5 0.7 5.7e-15 54.5 0.5 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain MMR_HSR1_C PF08438.5 KFM11220.1 - 0.098 12.8 0.3 4.4 7.5 0.0 2.4 2 0 0 2 2 2 0 GTPase of unknown function C-terminal Exo_endo_phos PF03372.18 KFM11221.1 - 1.3e-35 123.5 0.0 1.8e-35 123.0 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.22 KFM11221.1 - 4.2e-27 94.6 0.0 8e-27 93.7 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain zf-H2C2_2 PF13465.1 KFM11222.1 - 3.4e-30 102.8 46.5 1.5e-08 34.5 0.3 7.4 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2 PF00096.21 KFM11222.1 - 2.8e-27 93.3 39.9 0.00015 21.9 1.0 6.7 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM11222.1 - 1e-18 66.2 35.0 0.0026 17.9 0.5 6.7 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM11222.1 - 5.6e-06 26.3 23.2 0.011 15.7 1.5 6.2 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding Marek_A PF02124.10 KFM11222.1 - 0.0065 15.9 1.4 0.76 9.1 0.1 3.1 2 1 1 3 3 3 1 Marek's disease glycoprotein A zf-met PF12874.2 KFM11222.1 - 0.077 13.2 0.5 0.077 13.2 0.4 5.7 7 0 0 7 7 7 0 Zinc-finger of C2H2 type Sua5_yciO_yrdC PF01300.13 KFM11223.1 - 1.4e-24 86.3 0.0 1.7e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Telomere recombination Pkinase_Tyr PF07714.12 KFM11224.1 - 1.2e-76 257.2 0.0 2.6e-76 256.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Ephrin_lbd PF01404.14 KFM11224.1 - 3.7e-75 251.5 0.0 6.4e-75 250.8 0.0 1.4 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase PF00069.20 KFM11224.1 - 3.6e-31 108.2 0.0 7.9e-31 107.1 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain fn3 PF00041.16 KFM11224.1 - 9.9e-23 80.0 7.6 1.4e-10 41.1 0.0 3.6 3 1 0 3 3 3 2 Fibronectin type III domain EphA2_TM PF14575.1 KFM11224.1 - 1.4e-19 70.1 0.0 3.1e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SAM_1 PF00536.25 KFM11224.1 - 1.7e-18 66.5 0.0 3.1e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFM11224.1 - 1.9e-16 59.6 0.0 5.2e-16 58.2 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) GCC2_GCC3 PF07699.8 KFM11224.1 - 0.00015 21.2 1.4 0.00015 21.2 1.0 3.0 3 1 0 3 3 3 1 GCC2 and GCC3 SusE PF14292.1 KFM11224.1 - 0.0031 17.3 3.4 0.18 11.6 1.7 2.4 2 0 0 2 2 2 1 SusE outer membrane protein Interfer-bind PF09294.5 KFM11224.1 - 0.0066 16.4 0.5 0.047 13.7 0.3 2.2 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III DPBB_1 PF03330.13 KFM11224.1 - 0.061 13.3 0.0 0.24 11.4 0.0 2.0 1 0 0 1 1 1 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Borealin PF10512.4 KFM11225.1 - 3.7e-29 100.9 0.0 3.7e-29 100.9 0.0 1.3 2 0 0 2 2 2 1 Cell division cycle-associated protein 8 Axin_b-cat_bind PF08833.5 KFM11225.1 - 0.21 11.2 2.0 0.6 9.8 0.0 2.4 2 1 0 2 2 2 0 Axin beta-catenin binding domain CK2S PF15011.1 KFM11226.1 - 1.7e-17 63.6 0.2 2.4e-17 63.2 0.1 1.2 1 0 0 1 1 1 1 Casein Kinase 2 substrate MutS_III PF05192.13 KFM11226.1 - 0.075 12.8 0.1 0.081 12.6 0.0 1.1 1 0 0 1 1 1 0 MutS domain III TSP_1 PF00090.14 KFM11227.1 - 0.0018 18.3 5.2 0.0018 18.3 3.6 4.0 3 1 1 4 4 4 1 Thrombospondin type 1 domain Fer4_3 PF12798.2 KFM11227.1 - 0.099 13.2 11.6 1.9 9.2 0.3 5.2 5 2 0 5 5 5 0 4Fe-4S binding domain NGP1NT PF08153.7 KFM11228.1 - 7.5e-46 155.2 0.4 2.3e-45 153.7 0.2 1.9 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 KFM11228.1 - 8.3e-18 64.4 0.4 1.2e-13 51.0 0.0 3.6 3 1 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.13 KFM11228.1 - 2.1e-05 23.8 0.0 0.00013 21.2 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 KFM11228.1 - 0.00058 19.0 0.1 0.0023 17.1 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KFM11228.1 - 0.0024 17.3 0.0 0.68 9.3 0.0 3.4 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain Arf PF00025.16 KFM11228.1 - 0.0061 15.8 0.2 0.23 10.7 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family Dynamin_N PF00350.18 KFM11228.1 - 0.69 9.7 13.7 1.9 8.2 0.0 5.1 3 2 1 4 4 4 0 Dynamin family Ax_dynein_light PF10211.4 KFM11229.1 - 7.1e-74 247.7 21.1 7.9e-74 247.5 14.6 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain Mei5 PF10376.4 KFM11229.1 - 0.95 8.9 14.5 1.7 8.1 10.0 1.4 1 0 0 1 1 1 0 Double-strand recombination repair protein Phage_min_cap2 PF06152.6 KFM11229.1 - 1.5 7.7 9.9 2.1 7.2 6.8 1.2 1 0 0 1 1 1 0 Phage minor capsid protein 2 FHA PF00498.21 KFM11230.1 - 3.4e-19 68.7 0.0 6.6e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 FHA domain SURF2 PF05477.6 KFM11231.1 - 0.019 14.0 2.1 0.023 13.8 1.4 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) NuA4 PF09340.5 KFM11231.1 - 0.054 13.1 0.2 0.054 13.1 0.2 2.1 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 Myc_N PF01056.13 KFM11231.1 - 0.15 11.1 4.3 0.19 10.8 3.0 1.1 1 0 0 1 1 1 0 Myc amino-terminal region RNase_Zc3h12a PF11977.3 KFM11232.1 - 5.4e-53 178.9 0.0 7.9e-53 178.4 0.0 1.2 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain zf-CCCH PF00642.19 KFM11232.1 - 0.013 15.1 6.8 0.031 13.9 1.9 3.0 2 1 1 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KFM11232.1 - 1.1 9.4 10.5 0.57 10.2 4.8 2.3 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type ANF_receptor PF01094.23 KFM11233.1 - 3.2e-63 213.6 0.0 4.4e-63 213.1 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.21 KFM11233.1 - 1.9e-54 183.4 0.5 7.2e-54 181.5 0.1 2.0 2 0 0 2 2 2 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.4 KFM11233.1 - 1.4e-28 98.6 1.2 1.2e-27 95.6 0.1 2.9 3 0 0 3 3 3 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.15 KFM11233.1 - 8.8e-22 77.4 0.0 1.5e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.1 KFM11233.1 - 4.8e-05 22.8 0.0 7.1e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein DUF2569 PF10754.4 KFM11233.1 - 0.007 16.5 1.1 0.018 15.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2569) fn3 PF00041.16 KFM11234.1 - 1.1e-09 38.2 0.1 7e-08 32.4 0.0 3.4 4 0 0 4 4 4 1 Fibronectin type III domain Lep_receptor_Ig PF06328.6 KFM11234.1 - 1.8e-08 34.1 0.1 6.8e-08 32.2 0.0 1.9 2 0 0 2 2 2 1 Ig-like C2-type domain EpoR_lig-bind PF09067.5 KFM11234.1 - 0.0047 16.8 0.1 0.025 14.5 0.0 2.3 2 1 0 2 2 2 1 Erythropoietin receptor, ligand binding Oscp1 PF10188.4 KFM11235.1 - 5.8e-59 198.7 3.3 7.9e-59 198.3 2.3 1.1 1 0 0 1 1 1 1 Organic solute transport protein 1 LSM PF01423.17 KFM11236.1 - 7.9e-11 41.3 0.2 1.2e-10 40.7 0.1 1.2 1 0 0 1 1 1 1 LSM domain RRM_6 PF14259.1 KFM11236.1 - 0.058 13.3 0.1 1.4 8.9 0.0 2.3 1 1 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 KFM11237.1 - 2.3e-39 135.1 0.0 3.3e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM11237.1 - 9.8e-21 73.9 0.1 1.6e-20 73.2 0.0 1.3 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM11237.1 - 1.5e-05 24.1 0.1 3.6e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFM11237.1 - 0.062 12.3 0.1 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FAM176 PF14851.1 KFM11238.1 - 1.9e-53 180.2 0.0 2.2e-53 180.0 0.0 1.0 1 0 0 1 1 1 1 FAM176 family Nucleoplasmin PF03066.10 KFM11238.1 - 0.025 14.1 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Nucleoplasmin PAXIP1_C PF15364.1 KFM11238.1 - 0.069 13.0 1.0 0.11 12.4 0.7 1.2 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein CENP-B_dimeris PF09026.5 KFM11238.1 - 0.11 12.7 3.3 0.17 12.1 2.3 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain THRAP3_BCLAF1 PF15440.1 KFM11239.1 - 2.9e-195 650.6 118.3 2.9e-195 650.6 82.0 2.8 3 0 0 3 3 3 1 THRAP3/BCLAF1 family Fn3-like PF14310.1 KFM11240.1 - 2.6e-15 56.0 0.7 4.5e-15 55.3 0.5 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3_C PF01915.17 KFM11240.1 - 0.032 13.7 0.8 0.053 13.0 0.5 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3_C PF01915.17 KFM11241.1 - 6.8e-17 61.7 0.0 8.2e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain K_channel_TID PF07941.6 KFM11241.1 - 0.0073 16.5 1.3 0.072 13.3 0.2 2.1 2 0 0 2 2 2 1 Potassium channel Kv1.4 tandem inactivation domain TRAPP PF04051.11 KFM11242.1 - 4.7e-40 136.5 0.0 5.3e-40 136.4 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component ADP_ribosyl_GH PF03747.9 KFM11243.1 - 3.4e-53 181.3 0.0 4.3e-53 180.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase TPR_11 PF13414.1 KFM11243.1 - 0.0058 16.2 0.0 0.034 13.7 0.0 2.1 2 0 0 2 2 2 1 TPR repeat Tektin PF03148.9 KFM11244.1 - 2.8e-128 427.7 41.9 3.2e-128 427.5 29.0 1.0 1 0 0 1 1 1 1 Tektin family DUF1664 PF07889.7 KFM11244.1 - 0.02 14.6 13.5 0.26 11.0 0.8 4.0 2 2 1 4 4 4 0 Protein of unknown function (DUF1664) DUF948 PF06103.6 KFM11244.1 - 0.57 10.0 5.9 5.9 6.8 0.3 3.8 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) TMF_DNA_bd PF12329.3 KFM11244.1 - 0.92 9.3 0.0 0.92 9.3 0.0 5.1 4 2 4 8 8 8 0 TATA element modulatory factor 1 DNA binding Prefoldin PF02996.12 KFM11244.1 - 2.1 8.0 15.2 18 4.9 0.9 4.6 4 0 0 4 4 4 0 Prefoldin subunit NPV_P10 PF05531.7 KFM11244.1 - 7.4 6.9 6.4 1.2e+02 2.9 0.0 4.0 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein V_ATPase_I PF01496.14 KFM11244.1 - 8.1 4.1 21.6 22 2.7 0.8 2.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Piwi PF02171.12 KFM11245.1 - 4.8e-110 367.2 0.0 6.7e-110 366.7 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 KFM11245.1 - 2.2e-39 133.8 1.3 3.6e-39 133.1 0.9 1.3 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 KFM11245.1 - 9.8e-22 76.0 0.0 1.9e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) DUF2678 PF10856.3 KFM11245.1 - 0.053 13.2 0.0 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) DUF3465 PF11948.3 KFM11245.1 - 0.064 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3465) Piwi PF02171.12 KFM11246.1 - 1.6e-106 355.6 0.0 2.3e-106 355.1 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 KFM11246.1 - 9.1e-40 135.0 2.8 1.7e-39 134.2 2.0 1.5 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 KFM11246.1 - 1.6e-21 75.3 0.0 3.1e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) ATP_bind_4 PF01902.12 KFM11246.1 - 0.085 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 ATP-binding region DUF4653 PF15546.1 KFM11248.1 - 5.6e-80 268.0 0.0 6.7e-80 267.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4653) Proteasome PF00227.21 KFM11249.1 - 1.2e-35 122.5 0.0 1.3e-35 122.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TF_AP-2 PF03299.9 KFM11250.1 - 9.3e-96 319.3 0.0 1.1e-95 319.1 0.0 1.0 1 0 0 1 1 1 1 Transcription factor AP-2 Neurochondrin PF05536.6 KFM11251.1 - 2.6e-200 666.3 0.2 3.1e-200 666.1 0.2 1.0 1 0 0 1 1 1 1 Neurochondrin Y_Y_Y PF07495.8 KFM11252.1 - 3.7e-13 49.0 1.2 0.0064 16.2 0.0 5.2 5 0 0 5 5 5 3 Y_Y_Y domain Big_3_4 PF13754.1 KFM11252.1 - 4.2e-12 46.2 11.6 0.00045 20.4 0.0 5.2 4 0 0 4 4 4 3 Bacterial Ig-like domain (group 3) DUF4625 PF15418.1 KFM11252.1 - 5.3e-12 45.9 0.1 0.017 15.2 0.0 4.5 4 0 0 4 4 4 4 Domain of unknown function (DUF4625) PKD PF00801.15 KFM11252.1 - 9.8e-08 31.6 20.6 0.015 14.9 0.0 6.4 7 0 0 7 7 7 4 PKD domain He_PIG PF05345.7 KFM11252.1 - 1.6e-05 24.8 9.2 0.2 11.7 0.0 5.3 6 0 0 6 6 6 2 Putative Ig domain Cadherin PF00028.12 KFM11252.1 - 0.00057 20.0 4.6 5 7.4 0.1 4.8 4 0 0 4 4 4 1 Cadherin domain EGF_2 PF07974.8 KFM11252.1 - 0.00099 19.2 4.4 0.0035 17.4 3.1 1.9 1 0 0 1 1 1 1 EGF-like domain fn3 PF00041.16 KFM11252.1 - 0.0025 17.9 0.5 0.44 10.7 0.0 3.7 3 0 0 3 3 3 1 Fibronectin type III domain NOD PF06816.8 KFM11252.1 - 0.73 8.9 2.9 3.7 6.7 0.2 2.8 2 1 1 3 3 3 0 NOTCH protein Ifi-6-16 PF06140.8 KFM11253.1 - 3.7e-23 81.0 25.1 4.2e-23 80.9 17.4 1.0 1 0 0 1 1 1 1 Interferon-induced 6-16 family HTH_6 PF01418.12 KFM11253.1 - 0.24 11.1 1.1 0.3 10.8 0.8 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family DUF3504 PF12012.3 KFM11254.1 - 1.6e-67 226.5 0.4 4.4e-67 225.1 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3504) zf-FCS PF06467.9 KFM11254.1 - 3.2e-59 196.3 96.0 1.3e-09 37.5 1.7 10.5 10 0 0 10 10 10 10 MYM-type Zinc finger with FCS sequence motif RRM_1 PF00076.17 KFM11255.1 - 1.8e-30 104.3 0.1 6.1e-15 54.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NOPS PF08075.6 KFM11255.1 - 3.1e-30 104.3 1.3 9.9e-30 102.7 0.9 2.0 1 0 0 1 1 1 1 NOPS (NUC059) domain RRM_6 PF14259.1 KFM11255.1 - 1.1e-22 79.7 0.4 2e-10 40.4 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM11255.1 - 3.3e-14 52.4 0.0 2.7e-06 27.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3256 PF11644.3 KFM11255.1 - 0.16 11.4 1.3 0.25 10.8 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3256) Exonuc_VII_L PF02601.10 KFM11255.1 - 6.1 5.9 9.6 8.3 5.4 6.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Tox-PL PF15644.1 KFM11255.1 - 7.4 7.3 6.4 83 3.9 0.0 3.0 2 1 1 3 3 3 0 Papain fold toxin 1 DoxX PF07681.7 KFM11256.1 - 0.0057 17.0 0.1 0.0059 17.0 0.1 1.1 1 0 0 1 1 1 1 DoxX DoxX_2 PF13564.1 KFM11256.1 - 0.014 15.3 0.1 0.014 15.3 0.1 1.1 1 0 0 1 1 1 0 DoxX-like family GKAP PF03359.8 KFM11257.1 - 3e-131 438.3 7.9 3e-131 438.3 5.5 2.0 2 0 0 2 2 2 1 Guanylate-kinase-associated protein (GKAP) protein Connexin PF00029.14 KFM11259.1 - 3.3e-53 178.2 0.2 6.4e-53 177.3 0.1 1.4 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 KFM11259.1 - 1.7e-32 111.0 0.7 4.6e-32 109.6 0.5 1.8 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain Connexin43 PF03508.8 KFM11259.1 - 0.00078 18.6 3.9 0.0014 17.8 2.7 1.4 1 0 0 1 1 1 1 Gap junction alpha-1 protein (Cx43) Herpes_LMP2 PF07415.6 KFM11259.1 - 1 7.8 4.6 0.16 10.5 0.1 1.8 2 0 0 2 2 2 0 Gammaherpesvirus latent membrane protein (LMP2) protein Connexin PF00029.14 KFM11260.1 - 3.6e-51 171.7 0.5 3.6e-51 171.7 0.3 1.8 2 1 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 KFM11260.1 - 5.8e-26 90.0 3.1 1.4e-25 88.8 2.1 1.7 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain UCR_TM PF02921.9 KFM11260.1 - 0.049 13.8 0.8 0.14 12.4 0.0 2.0 2 0 0 2 2 2 0 Ubiquinol cytochrome reductase transmembrane region Rad60-SLD_2 PF13881.1 KFM11260.1 - 0.099 12.5 0.2 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like 7tm_1 PF00001.16 KFM11260.1 - 0.11 11.6 5.3 0.48 9.5 0.6 2.2 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) MFS_Mycoplasma PF07672.8 KFM11260.1 - 0.32 10.1 4.5 3.5 6.7 0.1 2.8 3 0 0 3 3 3 0 Mycoplasma MFS transporter PRA1 PF03208.14 KFM11260.1 - 0.33 10.2 3.0 0.96 8.7 0.0 2.8 3 1 0 3 3 3 0 PRA1 family protein Connexin PF00029.14 KFM11261.1 - 1.8e-47 159.8 0.3 1.8e-47 159.8 0.2 1.7 2 1 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 KFM11261.1 - 6e-26 90.0 6.5 1.6e-25 88.7 4.5 1.8 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain CUB PF00431.15 KFM11264.1 - 1.1e-283 920.3 0.0 3.7e-26 91.3 0.0 12.3 12 0 0 12 12 12 12 CUB domain Sushi PF00084.15 KFM11264.1 - 1.4e-258 835.5 173.4 4e-13 49.4 0.4 27.5 27 0 0 27 27 27 27 Sushi domain (SCR repeat) CUB_2 PF02408.15 KFM11264.1 - 3.8e-22 78.0 18.8 0.00016 21.1 0.5 10.9 12 0 0 12 12 12 6 CUB-like domain HRM PF02793.17 KFM11264.1 - 1 9.3 77.2 0.9 9.5 0.0 16.1 15 2 1 16 16 16 0 Hormone receptor domain ArfGap PF01412.13 KFM11265.1 - 4.5e-33 113.5 0.4 7.6e-33 112.7 0.1 1.5 1 1 0 1 1 1 1 Putative GTPase activating protein for Arf CBFD_NFYB_HMF PF00808.18 KFM11266.1 - 3.9e-22 78.0 2.5 1.9e-21 75.8 1.1 2.3 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KFM11266.1 - 2.4e-12 46.8 0.3 7.1e-12 45.2 0.2 1.8 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 KFM11266.1 - 0.098 12.4 0.1 0.23 11.2 0.1 1.6 1 0 0 1 1 1 0 CENP-S associating Centromere protein X YfhO PF09586.5 KFM11266.1 - 4.4 5.1 13.0 5.4 4.9 9.0 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Ion_trans_2 PF07885.11 KFM11267.1 - 6.6e-12 44.9 4.5 2.2e-11 43.2 3.1 1.8 1 1 0 1 1 1 1 Ion channel Ion_trans PF00520.26 KFM11267.1 - 2e-07 30.4 1.2 2.5e-07 30.1 0.8 1.3 1 0 0 1 1 1 1 Ion transport protein Lig_chan PF00060.21 KFM11267.1 - 0.043 13.5 0.6 0.065 12.9 0.4 1.5 1 1 0 1 1 1 0 Ligand-gated ion channel DUF2798 PF11391.3 KFM11267.1 - 0.088 12.5 3.7 2 8.2 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2798) FAD-SLDH PF12318.3 KFM11267.1 - 0.62 9.7 4.9 3.7 7.2 3.4 1.9 1 1 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase KCNQ_channel PF03520.9 KFM11268.1 - 4.6e-84 280.7 0.4 6e-84 280.3 0.3 1.1 1 0 0 1 1 1 1 KCNQ voltage-gated potassium channel TMEM95 PF15203.1 KFM11268.1 - 0.063 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 TMEM95 family EF-hand_1 PF00036.27 KFM11269.1 - 3.5e-21 72.8 0.0 3.9e-07 28.8 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 KFM11269.1 - 1.2e-17 62.1 0.0 3.5e-06 26.4 0.0 3.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 KFM11269.1 - 2.2e-17 62.9 0.1 1.6e-07 31.3 0.1 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KFM11269.1 - 4.6e-16 57.3 0.2 3.5e-06 26.0 0.0 3.6 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 KFM11269.1 - 1.9e-11 43.4 0.1 0.046 13.3 0.0 4.1 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_2 PF09068.6 KFM11269.1 - 6.2e-05 23.0 0.0 7.2 6.7 0.0 3.3 2 1 1 3 3 3 3 EF hand Gelsolin PF00626.17 KFM11269.1 - 0.0085 15.7 2.1 0.016 14.8 1.4 1.6 1 1 0 1 1 1 1 Gelsolin repeat Toprim_2 PF13155.1 KFM11269.1 - 0.0093 16.2 0.0 2.7 8.3 0.0 2.2 1 1 1 2 2 2 2 Toprim-like EF-hand_9 PF14658.1 KFM11269.1 - 0.029 14.2 0.0 7.6 6.5 0.0 3.3 2 2 0 2 2 2 0 EF-hand domain EF-hand_10 PF14788.1 KFM11269.1 - 0.077 12.6 0.0 4.8 6.9 0.0 2.6 2 0 0 2 2 2 0 EF hand HPIP PF15226.1 KFM11270.1 - 0.032 14.2 0.4 0.062 13.3 0.2 1.5 2 0 0 2 2 2 0 HCF-1 beta-propeller-interacting protein family Y_phosphatase PF00102.22 KFM11271.1 - 1.9e-12 47.0 0.0 7.7e-09 35.2 0.0 2.0 1 1 1 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.15 KFM11271.1 - 8.1e-09 35.1 0.0 1.2e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFM11271.1 - 0.043 14.0 0.2 0.091 13.0 0.1 1.7 1 1 0 1 1 1 0 Tyrosine phosphatase family KH_1 PF00013.24 KFM11272.1 - 6.2e-09 35.3 0.1 1.2e-08 34.4 0.1 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 KFM11272.1 - 2.2e-08 33.5 0.1 4.1e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 KH domain KH_5 PF13184.1 KFM11272.1 - 0.015 15.0 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 NusA-like KH domain KH_2 PF07650.12 KFM11272.1 - 0.092 12.3 0.1 0.18 11.3 0.1 1.4 1 0 0 1 1 1 0 KH domain Tmp39 PF10271.4 KFM11273.1 - 1.1e-198 660.1 16.4 1.3e-198 659.9 11.4 1.0 1 0 0 1 1 1 1 Putative transmembrane protein MARCKS PF02063.12 KFM11274.1 - 7.3e-14 52.3 51.7 7.5e-11 42.4 35.8 2.4 1 1 0 1 1 1 1 MARCKS family Hist_deacetyl PF00850.14 KFM11275.1 - 6.5e-82 275.2 0.1 9.3e-82 274.7 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Pkinase_Tyr PF07714.12 KFM11276.1 - 5.4e-87 291.1 0.0 8.1e-87 290.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM11276.1 - 1.9e-41 141.9 0.0 4.3e-41 140.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 KFM11276.1 - 1.3e-27 95.3 0.4 2.4e-27 94.5 0.3 1.5 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.23 KFM11276.1 - 2.9e-15 55.3 0.1 7.4e-15 54.0 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFM11276.1 - 2.7e-11 42.8 0.0 6.2e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFM11276.1 - 1.4e-07 30.8 0.0 3.2e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF3259 PF11652.3 KFM11277.1 - 4.3e-42 142.1 2.3 6.3e-42 141.6 1.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3259) DUF2388 PF09498.5 KFM11277.1 - 0.00077 19.0 0.3 0.0015 18.1 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2388) DUF4618 PF15397.1 KFM11277.1 - 0.0053 16.1 0.1 0.0074 15.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) DUF4164 PF13747.1 KFM11277.1 - 0.048 13.7 1.7 0.092 12.8 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) LURAP PF14854.1 KFM11277.1 - 0.09 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Leucine rich adaptor protein DUF4404 PF14357.1 KFM11277.1 - 0.1 13.0 1.5 0.15 12.4 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) FlxA PF14282.1 KFM11277.1 - 0.11 12.4 1.6 0.19 11.7 1.1 1.3 1 0 0 1 1 1 0 FlxA-like protein Myotub-related PF06602.9 KFM11278.1 - 2.4e-50 171.2 1.2 3.3e-24 85.3 0.2 2.1 2 0 0 2 2 2 2 Myotubularin-like phosphatase domain GRAM PF02893.15 KFM11278.1 - 0.12 11.9 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 GRAM domain WD40 PF00400.27 KFM11279.1 - 1.1e-34 116.9 0.6 2.4e-09 36.6 1.0 6.1 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.3 KFM11279.1 - 0.064 11.3 0.1 0.31 9.1 0.0 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 DUF4159 PF13709.1 KFM11279.1 - 0.065 12.3 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4159) Rho_Binding PF08912.6 KFM11279.1 - 0.072 13.3 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 Rho Binding UPF0546 PF10639.4 KFM11280.1 - 7.9e-23 80.4 0.4 8.6e-23 80.3 0.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 DCX PF03607.12 KFM11281.1 - 1.7e-17 62.7 0.0 2.4e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Doublecortin DCX PF03607.12 KFM11282.1 - 5e-22 77.2 0.0 6.1e-22 76.9 0.0 1.1 1 0 0 1 1 1 1 Doublecortin IQ PF00612.22 KFM11283.1 - 0.0057 16.1 1.6 0.014 15.0 1.1 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif Taxilin PF09728.4 KFM11284.1 - 1.2e-116 389.1 74.0 1.3e-116 389.0 51.3 1.0 1 0 0 1 1 1 1 Myosin-like coiled-coil protein DUF869 PF05911.6 KFM11284.1 - 0.00064 18.0 9.8 0.00064 18.0 6.8 2.4 1 1 1 2 2 2 1 Plant protein of unknown function (DUF869) AAA_13 PF13166.1 KFM11284.1 - 0.93 7.8 49.5 0.039 12.4 8.0 2.1 1 1 1 2 2 2 0 AAA domain SpoVAD PF07451.6 KFM11284.1 - 3 6.2 8.3 5.5 5.3 0.6 2.3 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) Laminin_I PF06008.9 KFM11284.1 - 3.2 6.9 57.0 0.1 11.8 21.6 3.4 1 1 2 3 3 3 0 Laminin Domain I FlaC_arch PF05377.6 KFM11284.1 - 4.1 7.3 18.9 0.92 9.4 0.7 4.1 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Shugoshin_N PF07558.6 KFM11284.1 - 4.4 7.0 19.6 0.94 9.2 0.7 4.7 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region Tropomyosin PF00261.15 KFM11284.1 - 8.4 5.4 66.7 0.53 9.3 20.0 2.3 1 1 1 2 2 2 0 Tropomyosin Arm PF00514.18 KFM11285.1 - 3.8e-89 289.8 18.8 4e-14 51.8 0.0 9.0 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFM11285.1 - 4.5e-27 94.1 0.0 6.8e-09 35.8 0.0 5.6 2 1 3 6 6 6 4 HEAT repeats IBB PF01749.15 KFM11285.1 - 6e-26 90.4 2.1 1.1e-25 89.6 1.5 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 KFM11285.1 - 3.2e-22 78.3 5.1 1.1e-06 28.8 0.0 5.9 4 2 2 6 6 6 5 HEAT-like repeat HEAT PF02985.17 KFM11285.1 - 1.3e-12 46.6 14.9 0.0005 19.9 0.0 8.0 10 0 0 10 10 10 2 HEAT repeat Arm_2 PF04826.8 KFM11285.1 - 6.4e-08 32.0 0.0 0.014 14.4 0.0 2.8 1 1 2 3 3 3 2 Armadillo-like RICTOR_V PF14668.1 KFM11285.1 - 3.5e-06 26.8 4.0 0.96 9.4 0.0 5.2 5 1 1 6 6 6 2 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.3 KFM11285.1 - 1.6e-05 24.8 0.0 0.26 11.2 0.0 4.4 2 1 3 5 5 5 1 V-ATPase subunit H HEAT_PBS PF03130.11 KFM11285.1 - 0.00043 20.4 0.2 7.2 7.3 0.0 4.9 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.4 KFM11285.1 - 0.009 14.3 0.2 0.25 9.5 0.0 2.3 1 1 2 3 3 3 1 Proteasome non-ATPase 26S subunit BSD PF03909.12 KFM11286.1 - 7e-18 64.1 4.7 8.3e-18 63.8 0.2 2.3 2 0 0 2 2 2 1 BSD domain BTB PF00651.26 KFM11287.1 - 2e-25 88.9 0.2 3.3e-25 88.2 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 KFM11287.1 - 1.5e-11 43.9 26.9 3.4e-09 36.5 1.3 4.1 4 0 0 4 4 4 3 Zinc-finger double domain DUF3342 PF11822.3 KFM11287.1 - 7.3e-06 25.3 0.1 7.3e-06 25.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) zf-C2H2 PF00096.21 KFM11287.1 - 8.5e-06 25.8 1.3 8.5e-06 25.8 0.9 4.6 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM11287.1 - 1.5e-05 24.9 9.5 0.00011 22.2 1.2 4.3 5 0 0 5 5 5 2 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KFM11287.1 - 0.00061 19.8 0.6 0.00061 19.8 0.4 3.0 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-met PF12874.2 KFM11287.1 - 0.0074 16.4 0.1 0.0074 16.4 0.1 4.4 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFM11287.1 - 0.05 13.7 5.0 0.12 12.5 0.0 3.5 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding SRC-1 PF08832.5 KFM11287.1 - 0.06 14.0 0.5 0.18 12.5 0.3 1.8 1 0 0 1 1 1 0 Steroid receptor coactivator RRN7 PF11781.3 KFM11287.1 - 2.7 7.5 8.3 13 5.4 0.2 3.6 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 BTB PF00651.26 KFM11288.1 - 8e-27 93.4 0.4 1.3e-26 92.7 0.3 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 KFM11288.1 - 6e-09 35.7 2.4 6e-09 35.7 1.7 3.8 3 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM11288.1 - 2.4e-06 27.4 18.7 0.00031 20.8 0.9 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger DUF3342 PF11822.3 KFM11288.1 - 2.6e-06 26.8 0.1 2.6e-06 26.8 0.1 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF3342) zf-C2H2 PF00096.21 KFM11288.1 - 3e-05 24.0 23.7 6.3e-05 23.0 1.1 4.0 4 0 0 4 4 3 2 Zinc finger, C2H2 type BTB_2 PF02214.17 KFM11288.1 - 0.00054 20.1 0.0 0.0011 19.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-met PF12874.2 KFM11288.1 - 0.012 15.8 2.7 0.11 12.7 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 KFM11288.1 - 0.02 15.0 2.2 0.02 15.0 1.5 3.0 3 0 0 3 3 2 0 C2H2-type zinc-finger domain DUF1722 PF08349.6 KFM11288.1 - 0.062 13.1 0.0 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) zf-C2H2_jaz PF12171.3 KFM11288.1 - 0.15 12.2 2.4 0.54 10.4 0.1 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 KFM11288.1 - 0.83 9.6 8.5 5.7 6.9 2.8 3.6 2 1 0 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 KFM11288.1 - 4.4 7.1 17.8 8.5 6.2 4.3 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain BTB PF00651.26 KFM11290.1 - 7.4e-26 90.3 0.6 1.4e-25 89.4 0.4 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 KFM11290.1 - 6.8e-09 35.5 2.8 6.8e-09 35.5 1.9 4.0 3 0 0 3 3 3 1 Zinc-finger double domain DUF3342 PF11822.3 KFM11290.1 - 3.4e-06 26.4 0.2 3.4e-06 26.4 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) zf-C2H2_4 PF13894.1 KFM11290.1 - 2.5e-05 24.2 25.3 0.00011 22.2 1.3 3.8 3 1 0 3 3 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KFM11290.1 - 0.00016 21.7 1.4 0.00016 21.7 0.9 4.2 5 0 0 5 5 3 2 Zinc finger, C2H2 type zf-met PF12874.2 KFM11290.1 - 0.0011 19.0 2.5 0.019 15.1 0.1 3.5 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFM11290.1 - 0.0022 18.0 2.2 0.022 14.8 0.1 2.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding BTB_2 PF02214.17 KFM11290.1 - 0.0061 16.7 0.3 0.021 15.0 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Elf1 PF05129.8 KFM11290.1 - 0.048 13.3 6.2 3.7 7.3 4.1 3.2 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like Trm112p PF03966.11 KFM11290.1 - 0.051 13.9 1.8 0.17 12.2 1.3 1.9 1 0 0 1 1 1 0 Trm112p-like protein DUF3212 PF11486.3 KFM11290.1 - 0.056 13.1 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3212) DUF1722 PF08349.6 KFM11290.1 - 0.064 13.1 0.1 0.34 10.8 0.0 2.2 3 0 0 3 3 2 0 Protein of unknown function (DUF1722) Prim_Zn_Ribbon PF08273.7 KFM11290.1 - 0.071 13.2 1.8 0.33 11.0 1.3 2.2 1 1 0 1 1 1 0 Zinc-binding domain of primase-helicase zf-Di19 PF05605.7 KFM11290.1 - 0.26 11.4 11.5 1 9.5 5.0 2.6 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF2296 PF10058.4 KFM11290.1 - 0.89 9.3 7.4 9 6.1 0.1 3.1 3 1 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) Zn_Tnp_IS1595 PF12760.2 KFM11290.1 - 2.6 7.9 17.2 1.4 8.7 3.6 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain PHF5 PF03660.9 KFM11290.1 - 5.3 7.1 10.1 8.8 6.4 0.6 2.7 2 1 1 3 3 2 0 PHF5-like protein Archease PF01951.11 KFM11291.1 - 1.2e-47 161.3 0.1 1.5e-47 161.0 0.0 1.1 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) WD40 PF00400.27 KFM11292.1 - 3.9e-40 134.3 11.4 6.3e-09 35.3 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KFM11292.1 - 2.2e-30 104.3 0.2 6.5e-30 102.8 0.1 1.9 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 KFM11292.1 - 4.8e-05 23.1 0.9 0.014 15.1 0.1 3.2 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Capsid_NCLDV PF04451.7 KFM11292.1 - 0.024 13.6 0.0 0.048 12.6 0.0 1.4 1 0 0 1 1 1 0 Large eukaryotic DNA virus major capsid protein Filament PF00038.16 KFM11293.1 - 7.4e-21 74.9 33.4 1.3e-20 74.1 23.2 1.4 1 1 0 1 1 1 1 Intermediate filament protein Spc7 PF08317.6 KFM11293.1 - 0.001 17.8 29.7 0.0054 15.4 8.0 2.5 2 1 1 3 3 3 2 Spc7 kinetochore protein APG6 PF04111.7 KFM11293.1 - 0.0071 15.4 12.1 0.0071 15.4 8.4 2.2 2 0 0 2 2 2 1 Autophagy protein Apg6 Laminin_II PF06009.7 KFM11293.1 - 0.015 15.0 16.8 0.25 11.0 3.0 3.2 2 1 1 3 3 3 0 Laminin Domain II Reo_sigmaC PF04582.7 KFM11293.1 - 0.027 13.6 0.3 14 4.6 0.0 2.9 2 2 0 2 2 2 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 KFM11293.1 - 0.058 13.1 33.2 4.2 7.1 6.9 4.2 2 2 1 3 3 3 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 KFM11293.1 - 0.11 12.3 41.8 0.24 11.2 8.4 3.8 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.7 KFM11293.1 - 0.11 12.2 9.1 5.4 6.8 0.7 3.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus bZIP_1 PF00170.16 KFM11293.1 - 0.22 11.5 31.0 1.3 9.0 0.1 6.0 4 1 1 5 5 5 0 bZIP transcription factor NPV_P10 PF05531.7 KFM11293.1 - 0.38 11.0 7.4 25 5.2 0.6 4.1 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein COG2 PF06148.6 KFM11293.1 - 0.38 10.6 16.7 0.52 10.1 0.5 3.8 2 2 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.7 KFM11293.1 - 0.38 10.5 14.4 0.47 10.2 1.4 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) WEMBL PF05701.6 KFM11293.1 - 0.86 7.9 31.1 3.9e+02 -0.8 21.8 2.8 1 1 0 1 1 1 0 Weak chloroplast movement under blue light DUF948 PF06103.6 KFM11293.1 - 0.96 9.3 5.0 9.1 6.2 0.0 3.7 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF4618 PF15397.1 KFM11293.1 - 1.3 8.2 25.7 0.26 10.6 0.2 3.8 1 1 1 3 3 3 0 Domain of unknown function (DUF4618) Bacillus_HBL PF05791.6 KFM11293.1 - 1.5 8.1 14.1 1.7 7.9 0.7 3.2 2 2 2 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) Cob_adeno_trans PF01923.13 KFM11293.1 - 1.5 8.5 11.9 0.36 10.6 0.9 2.9 2 1 1 3 3 3 0 Cobalamin adenosyltransferase Cauli_AT PF03233.8 KFM11293.1 - 1.8 8.2 10.0 2.4 7.8 0.9 2.6 3 0 0 3 3 2 0 Aphid transmission protein DUF2937 PF11157.3 KFM11293.1 - 2.1 7.6 7.9 1.9 7.8 2.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DUF972 PF06156.8 KFM11293.1 - 2.6 8.4 28.5 4.2 7.7 0.1 4.9 2 2 1 3 3 3 0 Protein of unknown function (DUF972) DivIVA PF05103.8 KFM11293.1 - 2.8 7.9 24.7 22 5.0 4.9 4.1 2 2 0 2 2 2 0 DivIVA protein Seryl_tRNA_N PF02403.17 KFM11293.1 - 2.9 7.9 26.1 2.8 7.9 4.7 3.9 2 2 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Phlebovirus_NSM PF07246.6 KFM11293.1 - 3.3 6.7 15.2 0.68 9.0 1.7 2.8 2 2 1 3 3 3 0 Phlebovirus nonstructural protein NS-M FliJ PF02050.11 KFM11293.1 - 4.2 7.4 38.7 1.4 8.9 4.0 3.8 2 2 2 4 4 4 0 Flagellar FliJ protein Toxin_52 PF15605.1 KFM11293.1 - 5.1 7.0 9.5 6.1 6.7 0.3 3.7 3 2 1 4 4 4 0 Putative toxin 52 TMF_TATA_bd PF12325.3 KFM11293.1 - 5.4 6.7 38.6 3.5 7.3 9.8 4.2 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding Kinesin-relat_1 PF12711.2 KFM11293.1 - 6.6 7.2 35.1 0.056 13.8 1.2 4.9 1 1 4 5 5 5 0 Kinesin motor ATG16 PF08614.6 KFM11293.1 - 7.3 6.3 35.6 5.1 6.8 1.1 3.5 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Mnd1 PF03962.10 KFM11293.1 - 8.5 5.9 32.1 2.5 7.7 3.6 3.9 1 1 2 4 4 4 0 Mnd1 family IFT57 PF10498.4 KFM11293.1 - 9.7 4.8 27.6 1.5 7.5 2.6 3.0 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 Syntaxin PF00804.20 KFM11293.1 - 9.8 6.4 20.2 25 5.1 4.8 3.5 2 2 0 2 2 2 0 Syntaxin DUF2283 PF10049.4 KFM11294.1 - 8.5 6.3 13.1 14 5.6 0.1 3.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2283) tRNA-synt_1b PF00579.20 KFM11296.1 - 8.2e-75 251.6 0.0 1e-74 251.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA_bind PF01588.15 KFM11296.1 - 1e-26 92.6 0.1 2.4e-26 91.3 0.0 1.7 1 0 0 1 1 1 1 Putative tRNA binding domain fn3 PF00041.16 KFM11298.1 - 8.8e-11 41.7 0.4 2.1e-10 40.5 0.0 1.8 2 0 0 2 2 2 1 Fibronectin type III domain UPF0270 PF06794.7 KFM11298.1 - 0.082 12.6 0.2 6.6 6.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0270) DUF4366 PF14283.1 KFM11298.1 - 0.094 12.1 0.1 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) EF-hand_1 PF00036.27 KFM11299.1 - 2.9e-27 91.8 6.3 2.1e-07 29.7 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KFM11299.1 - 9.3e-26 89.7 1.2 1.2e-16 60.5 0.0 2.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 KFM11299.1 - 5.3e-24 82.4 3.1 1.7e-07 30.2 0.1 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 KFM11299.1 - 7.9e-23 78.2 0.2 2.5e-06 26.8 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 KFM11299.1 - 1.7e-18 65.9 4.2 5.9e-09 35.4 0.1 3.7 2 2 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFM11299.1 - 7e-08 32.4 0.1 0.00016 21.6 0.0 2.9 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFM11299.1 - 6.3e-07 29.0 0.8 0.23 11.2 0.0 3.4 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 KFM11299.1 - 0.0011 18.5 1.0 2.8 7.6 0.0 3.3 4 0 0 4 4 4 2 EF hand BCLP PF12304.3 KFM11300.1 - 1.3e-39 135.5 7.9 1e-19 70.6 0.8 2.0 1 1 1 2 2 2 2 Beta-casein like protein IBR PF01485.16 KFM11301.1 - 2.2e-12 46.6 33.4 1.9e-09 37.2 5.4 3.5 3 0 0 3 3 3 2 IBR domain ADK PF00406.17 KFM11302.1 - 8.8e-52 174.9 0.0 1e-51 174.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 KFM11302.1 - 9.4e-14 50.7 0.0 3e-13 49.1 0.0 1.9 2 0 0 2 2 2 1 Adenylate kinase, active site lid Orn_Arg_deC_N PF02784.11 KFM11303.1 - 2.7e-63 213.4 0.0 3.4e-63 213.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 KFM11303.1 - 1.6e-09 37.4 0.0 2.8e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ndufs5 PF10200.4 KFM11304.1 - 7.7e-06 25.8 0.1 8.7e-06 25.6 0.1 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Spectrin PF00435.16 KFM11305.1 - 2.5e-234 760.5 428.2 8.3e-18 64.6 3.6 41.8 39 4 1 40 40 40 35 Spectrin repeat CH PF00307.26 KFM11305.1 - 1.6e-38 131.0 8.4 3e-19 69.0 0.0 6.1 6 0 0 6 6 6 2 Calponin homology (CH) domain GAS2 PF02187.12 KFM11305.1 - 2.4e-38 129.7 1.0 6.6e-38 128.3 0.7 1.8 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain EF-hand_1 PF00036.27 KFM11305.1 - 2.8e-12 44.9 2.2 5.7e-05 22.1 0.0 3.0 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 KFM11305.1 - 1.4e-09 37.9 3.2 2.1e-09 37.3 0.4 2.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KFM11305.1 - 1.6e-09 36.8 4.1 0.00068 19.3 0.3 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 KFM11305.1 - 4.6e-09 35.7 1.5 2.2e-08 33.5 0.0 3.1 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.1 KFM11305.1 - 1.2e-08 33.9 4.1 3.9e-05 22.8 1.0 3.0 2 0 0 2 2 2 2 EF hand CAMSAP_CH PF11971.3 KFM11305.1 - 2.1e-06 27.2 0.0 0.00013 21.5 0.0 3.2 2 0 0 2 2 2 1 CAMSAP CH domain Laminin_II PF06009.7 KFM11305.1 - 8.8e-05 22.2 3.1 8.8e-05 22.2 2.2 23.7 18 6 5 27 27 26 3 Laminin Domain II TraG_N PF07916.6 KFM11305.1 - 1.5 7.1 0.5 5.6 5.2 0.3 2.0 1 0 0 1 1 1 0 TraG-like protein, N-terminal region TGF_beta PF00019.15 KFM11307.1 - 1.8e-41 140.6 3.7 2.9e-41 140.0 2.6 1.3 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.13 KFM11307.1 - 2.4e-33 115.3 0.0 3.6e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 TGF-beta propeptide Hairy_orange PF07527.8 KFM11308.1 - 1.1e-11 44.3 0.0 2.3e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Hairy Orange HLH PF00010.21 KFM11308.1 - 0.00012 21.7 0.0 0.00025 20.6 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain 5-nucleotidase PF06189.7 KFM11309.1 - 2.9e-115 383.6 0.0 7.3e-114 379.0 0.0 2.0 1 1 1 2 2 2 2 5'-nucleotidase EF-hand_1 PF00036.27 KFM11310.1 - 6.3e-24 81.4 14.9 2.3e-08 32.7 0.0 4.9 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 KFM11310.1 - 1e-21 74.8 5.6 5.2e-07 29.0 0.1 4.6 4 1 1 5 5 5 3 EF-hand domain EF-hand_7 PF13499.1 KFM11310.1 - 1.8e-20 72.8 6.2 1.9e-12 47.1 0.5 3.2 2 2 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KFM11310.1 - 3.6e-16 57.6 15.0 1.1e-06 27.6 0.3 4.7 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 KFM11310.1 - 6.6e-15 54.4 9.7 2.3e-07 30.3 0.5 4.4 1 1 3 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFM11310.1 - 4.8e-05 23.3 2.1 0.021 14.8 0.4 3.4 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFM11310.1 - 0.0062 16.2 7.3 4.1 7.1 0.4 3.6 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand Homez PF11569.3 KFM11310.1 - 0.068 12.2 0.1 0.15 11.1 0.1 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Caleosin PF05042.8 KFM11310.1 - 0.25 10.8 1.6 3.8 7.0 1.1 2.6 1 1 0 1 1 1 0 Caleosin related protein EF-hand_10 PF14788.1 KFM11310.1 - 1.2 8.8 6.3 15 5.3 0.2 3.3 4 0 0 4 4 4 0 EF hand AMH_N PF04709.7 KFM11311.1 - 1.6e-69 234.6 6.9 6.5e-48 163.5 3.0 2.1 1 1 1 2 2 2 2 Anti-Mullerian hormone, N terminal region TGF_beta PF00019.15 KFM11311.1 - 5.5e-20 71.5 0.2 8.6e-20 70.9 0.2 1.3 1 0 0 1 1 1 1 Transforming growth factor beta like domain zf-met PF12874.2 KFM11313.1 - 1.2e-06 28.4 2.1 1.2e-06 28.4 1.4 1.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.4 KFM11313.1 - 0.01 15.4 0.1 0.017 14.6 0.1 1.3 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein PRP4 PF08799.6 KFM11313.1 - 0.049 12.8 2.5 0.087 12.1 1.7 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like PH PF00169.24 KFM11314.1 - 5.3e-09 36.2 0.3 8.9e-09 35.4 0.2 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KFM11314.1 - 0.00031 20.9 0.0 0.00046 20.4 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 KFM11314.1 - 0.0057 16.5 0.0 0.0078 16.0 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 KFM11314.1 - 0.0097 16.0 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 KFM11314.1 - 0.013 15.5 0.0 0.15 12.1 0.0 2.0 1 1 1 2 2 2 0 Pleckstrin homology domain DOT1 PF08123.8 KFM11315.1 - 4.2e-83 277.6 0.4 1.2e-82 276.2 0.0 1.9 2 0 0 2 2 2 1 Histone methylation protein DOT1 Mob1_phocein PF03637.12 KFM11316.1 - 4.8e-79 264.0 0.5 5.4e-79 263.9 0.3 1.0 1 0 0 1 1 1 1 Mob1/phocein family Pkinase PF00069.20 KFM11317.1 - 4e-43 147.4 0.0 2e-39 135.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFM11317.1 - 8.8e-13 47.9 0.0 2.9e-11 42.9 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 KFM11317.1 - 0.0057 15.7 0.1 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KFM11317.1 - 0.072 12.0 0.0 0.18 10.7 0.0 1.6 1 1 0 1 1 1 0 Kinase-like PHR PF08005.7 KFM11318.1 - 3.6e-52 176.5 0.6 5.4e-52 175.9 0.4 1.3 1 0 0 1 1 1 1 PHR domain BTB PF00651.26 KFM11318.1 - 8.5e-22 77.2 0.3 6.6e-20 71.1 0.0 2.9 2 1 1 3 3 3 1 BTB/POZ domain BACK PF07707.10 KFM11318.1 - 7.5e-10 38.5 0.8 2.2e-08 33.8 0.1 3.0 1 1 1 2 2 2 1 BTB And C-terminal Kelch Pkinase PF00069.20 KFM11319.1 - 2.3e-32 112.1 0.0 3e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain CK1gamma_C PF12605.3 KFM11319.1 - 2e-20 73.1 3.6 3.6e-20 72.3 2.5 1.4 1 0 0 1 1 1 1 Casein kinase 1 gamma C terminal Pkinase_Tyr PF07714.12 KFM11319.1 - 3.6e-12 45.9 0.0 5.2e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SCAMP PF04144.8 KFM11320.1 - 2.8e-70 235.7 18.1 3.2e-70 235.6 12.5 1.0 1 0 0 1 1 1 1 SCAMP family zf-C4 PF00105.13 KFM11321.1 - 2e-33 114.4 13.6 3.9e-33 113.4 9.4 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) zf-A20 PF01754.11 KFM11322.1 - 2.4e-13 49.3 6.1 7.3e-13 47.8 4.2 1.9 1 0 0 1 1 1 1 A20-like zinc finger zf-AN1 PF01428.11 KFM11322.1 - 9.7e-12 44.5 5.7 9.7e-12 44.5 3.9 2.3 3 0 0 3 3 3 1 AN1-like Zinc finger MARCKS PF02063.12 KFM11322.1 - 0.00039 20.3 0.6 0.00055 19.8 0.4 1.1 1 0 0 1 1 1 1 MARCKS family zf-RING_5 PF14634.1 KFM11322.1 - 7.9 6.3 11.3 28 4.5 0.0 3.0 2 1 1 3 3 3 0 zinc-RING finger domain Abhydrolase_5 PF12695.2 KFM11323.1 - 4.5e-10 39.4 0.0 6.3e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFM11323.1 - 3.5e-05 23.7 0.0 4.8e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFM11323.1 - 0.0082 15.3 0.0 0.011 15.0 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KFM11323.1 - 0.011 15.2 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold UPF0227 PF05728.7 KFM11323.1 - 0.02 14.6 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) FSH1 PF03959.8 KFM11323.1 - 0.027 13.9 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DLH PF01738.13 KFM11323.1 - 0.036 13.3 0.0 0.054 12.7 0.0 1.1 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 KFM11323.1 - 0.12 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase RNase_T PF00929.19 KFM11324.1 - 5.8e-23 81.9 0.2 3.4e-22 79.4 0.1 2.2 2 0 0 2 2 2 1 Exonuclease E1-E2_ATPase PF00122.15 KFM11325.1 - 2.2e-14 53.0 0.1 8.6e-14 51.1 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 KFM11325.1 - 2.6e-14 53.8 1.6 1.1e-13 51.7 1.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFM11325.1 - 3e-14 53.9 0.0 1.2e-12 48.6 0.0 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFM11325.1 - 6.9e-13 48.3 0.2 1.1e-11 44.5 0.0 2.7 2 1 1 3 3 3 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFM11325.1 - 0.0013 18.3 0.4 0.0028 17.2 0.1 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Homeobox PF00046.24 KFM11326.1 - 5.7e-11 41.8 1.9 7.8e-11 41.4 1.3 1.2 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFM11326.1 - 6.3e-05 22.5 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain Nup88 PF10168.4 KFM11326.1 - 0.25 9.1 1.5 0.29 8.9 1.0 1.0 1 0 0 1 1 1 0 Nuclear pore component HLH PF00010.21 KFM11327.1 - 3.3e-10 39.5 1.0 7.2e-10 38.4 0.7 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4349 PF14257.1 KFM11327.1 - 0.089 12.0 1.2 0.15 11.2 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) UCR_6-4kD PF08997.5 KFM11328.1 - 8.7e-19 66.9 2.1 8.8e-19 66.9 1.4 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex, 6.4kD protein QCR10 PF09796.4 KFM11328.1 - 0.00088 18.8 2.2 0.0047 16.5 1.5 1.8 1 1 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) MBD_C PF14048.1 KFM11329.1 - 6.8e-37 125.9 0.4 1.2e-36 125.1 0.0 1.6 2 0 0 2 2 2 1 C-terminal domain of methyl-CpG binding protein 2 and 3 MBD PF01429.14 KFM11329.1 - 8.1e-10 38.1 0.2 7.9e-06 25.3 0.0 2.3 2 0 0 2 2 2 2 Methyl-CpG binding domain Ribosomal_60s PF00428.14 KFM11329.1 - 0.65 10.4 8.3 1.3 9.5 5.7 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein KH_1 PF00013.24 KFM11330.1 - 1.4e-19 69.4 3.1 1.1e-13 50.6 0.2 2.7 3 0 0 3 3 3 2 KH domain KH_3 PF13014.1 KFM11330.1 - 3.1e-10 39.4 0.1 1e-06 28.2 0.0 3.0 3 0 0 3 3 3 2 KH domain zf-C3HC4_3 PF13920.1 KFM11330.1 - 7.7e-10 38.2 10.9 1.2e-09 37.6 7.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM11330.1 - 7.3e-07 29.1 11.7 1.3e-06 28.3 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM11330.1 - 0.0007 19.1 10.9 0.0012 18.4 7.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM11330.1 - 0.0043 16.7 11.0 0.0081 15.8 7.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain KH_2 PF07650.12 KFM11330.1 - 0.043 13.3 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 KH domain zf-C3HC4_4 PF15227.1 KFM11330.1 - 1 9.3 9.5 2.8 7.8 6.6 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 KFM11330.1 - 1.3 8.8 6.3 3.1 7.6 4.4 1.6 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 KFM11330.1 - 3 7.4 9.2 6.6 6.3 6.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Myosin_head PF00063.16 KFM11331.1 - 1.3e-233 776.9 0.0 1.6e-233 776.7 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.22 KFM11331.1 - 1.1e-15 55.6 28.3 0.00018 20.8 1.2 4.9 4 0 0 4 4 4 4 IQ calmodulin-binding motif AAA_22 PF13401.1 KFM11331.1 - 0.0034 17.5 0.0 0.014 15.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFM11331.1 - 0.085 12.8 3.4 0.33 10.9 0.0 3.1 3 1 0 3 3 3 0 AAA ATPase domain Mito_carr PF00153.22 KFM11332.1 - 1.1e-44 150.0 0.3 3.1e-20 71.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Sec34 PF04136.10 KFM11333.1 - 7.5e-74 246.6 7.2 7.5e-74 246.6 5.0 3.9 5 0 0 5 5 5 1 Sec34-like family CLTH PF10607.4 KFM11333.1 - 0.0062 16.2 6.5 0.023 14.3 1.0 3.3 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain PP2C_C PF07830.8 KFM11333.1 - 0.016 15.2 0.7 0.18 11.9 0.1 2.8 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain Syntaxin-18_N PF10496.4 KFM11333.1 - 0.043 13.6 0.7 0.97 9.3 0.0 3.2 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus NPV_P10 PF05531.7 KFM11333.1 - 0.2 11.9 3.9 4.8 7.4 0.1 4.1 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Aha1_N PF09229.6 KFM11333.1 - 0.22 11.3 2.4 0.44 10.3 0.2 2.7 2 0 0 2 2 2 0 Activator of Hsp90 ATPase, N-terminal Syntaxin PF00804.20 KFM11333.1 - 5.5 7.2 10.3 4.4 7.5 0.5 4.4 4 2 0 4 4 4 0 Syntaxin FAM194 PF14977.1 KFM11334.1 - 2.6e-53 180.1 0.0 2.9e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 FAM194 protein MORN_2 PF07661.8 KFM11334.1 - 0.047 13.7 0.0 0.39 10.8 0.0 2.3 2 0 0 2 2 2 0 MORN repeat variant Chibby PF14645.1 KFM11337.1 - 0.0041 16.9 11.6 0.012 15.5 1.4 3.0 2 1 1 3 3 3 2 Chibby family HALZ PF02183.13 KFM11337.1 - 0.16 11.7 6.7 5.2 6.8 0.0 3.8 3 1 0 3 3 3 0 Homeobox associated leucine zipper zf-CCCH PF00642.19 KFM11338.1 - 6.3e-08 32.1 0.7 1.2e-07 31.1 0.5 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Peptidase_M14 PF00246.19 KFM11339.1 - 9e-85 284.6 0.0 1e-84 284.4 0.0 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase DUF1642 PF07852.6 KFM11339.1 - 0.049 13.9 1.0 0.1 12.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1642) CH PF00307.26 KFM11340.1 - 2.6e-81 268.7 1.1 1.8e-22 79.3 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 KFM11340.1 - 6.7e-10 38.9 0.0 1.9e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KFM11340.1 - 1.7e-08 33.1 0.2 0.0018 17.4 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KFM11340.1 - 6.4e-08 31.8 0.1 0.00092 18.9 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain CAMSAP_CH PF11971.3 KFM11340.1 - 1.7e-07 30.7 0.1 1.4e-06 27.8 0.0 2.6 3 0 0 3 3 3 1 CAMSAP CH domain EF-hand_8 PF13833.1 KFM11340.1 - 0.0042 16.6 0.0 0.018 14.6 0.0 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 KFM11340.1 - 0.26 10.7 1.9 0.48 9.8 0.1 2.4 3 0 0 3 3 3 0 EF hand LRR_8 PF13855.1 KFM11341.1 - 1.5e-23 82.3 12.7 3e-09 36.5 1.4 3.6 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KFM11341.1 - 3.9e-23 80.6 15.9 4.8e-08 32.4 1.9 5.6 3 2 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM11341.1 - 2.1e-16 57.4 15.8 0.02 14.8 0.4 9.0 8 0 0 8 8 8 5 Leucine Rich Repeat CH PF00307.26 KFM11341.1 - 4.6e-11 42.7 0.0 1.3e-10 41.2 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain LRR_7 PF13504.1 KFM11341.1 - 1.8e-10 39.2 12.8 0.48 10.8 0.2 7.9 7 0 0 7 7 7 3 Leucine rich repeat LRR_6 PF13516.1 KFM11341.1 - 7.7e-07 28.5 10.6 0.96 9.7 0.2 7.4 9 0 0 9 9 9 2 Leucine Rich repeat CAMSAP_CH PF11971.3 KFM11341.1 - 9.8e-05 21.9 0.0 0.00032 20.2 0.0 1.8 1 0 0 1 1 1 1 CAMSAP CH domain CDC24 PF06395.6 KFM11341.1 - 0.00013 21.9 0.0 0.0034 17.3 0.0 2.5 2 0 0 2 2 2 1 CDC24 Calponin 7tm_1 PF00001.16 KFM11342.1 - 8.2e-72 241.4 14.3 1.2e-71 240.8 9.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM11342.1 - 9e-15 54.5 18.6 1.5e-14 53.8 12.9 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM11342.1 - 0.00062 18.9 17.2 0.00062 18.9 11.9 3.0 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF1385 PF07136.6 KFM11342.1 - 0.0047 16.0 1.4 0.0047 16.0 1.0 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1385) ATP-grasp_2 PF08442.5 KFM11343.1 - 2.6e-75 252.2 0.9 3.6e-75 251.7 0.1 1.6 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.14 KFM11343.1 - 1.1e-26 93.2 2.6 2e-26 92.4 1.8 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 KFM11343.1 - 9.1e-10 38.1 0.3 1.7e-09 37.2 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 KFM11343.1 - 0.038 13.5 0.3 0.11 12.0 0.2 1.7 1 1 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 KFM11343.1 - 0.13 12.0 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Succ_CoA_lig PF13607.1 KFM11343.1 - 0.13 11.8 0.6 12 5.5 0.0 2.3 1 1 1 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain nsp7 PF08716.5 KFM11343.1 - 0.14 12.5 1.4 2 8.8 0.1 2.6 2 1 0 2 2 2 0 nsp7 replicase Med4 PF10018.4 KFM11344.1 - 4.2e-38 130.6 0.2 6.9e-38 129.9 0.1 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Tropomyosin PF00261.15 KFM11344.1 - 0.0014 17.7 4.1 0.0019 17.3 2.8 1.1 1 0 0 1 1 1 1 Tropomyosin DUF2019 PF09450.5 KFM11344.1 - 0.044 13.6 0.1 3.1 7.7 0.3 2.8 1 1 1 3 3 3 0 Domain of unknown function (DUF2019) Trans_reg_C PF00486.23 KFM11344.1 - 0.049 13.5 1.1 2.9 7.8 0.1 2.8 1 1 1 2 2 2 0 Transcriptional regulatory protein, C terminal Stathmin PF00836.14 KFM11344.1 - 0.14 11.7 6.5 0.25 10.9 4.5 1.4 1 0 0 1 1 1 0 Stathmin family Atg14 PF10186.4 KFM11344.1 - 0.34 9.8 4.7 0.42 9.4 3.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1682 PF07946.9 KFM11344.1 - 0.37 9.6 6.1 0.47 9.2 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF724 PF05266.9 KFM11344.1 - 0.53 9.8 5.9 0.75 9.3 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) BRICHOS PF04089.9 KFM11345.1 - 4.3e-28 97.0 0.0 7.1e-28 96.3 0.0 1.4 1 0 0 1 1 1 1 BRICHOS domain RB_A PF01858.12 KFM11346.1 - 2e-78 262.5 0.4 2e-78 262.5 0.3 1.6 2 0 0 2 2 2 1 Retinoblastoma-associated protein A domain DUF3452 PF11934.3 KFM11346.1 - 3.3e-33 113.9 4.7 1.1e-30 105.8 2.7 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3452) 7tm_1 PF00001.16 KFM11347.1 - 3.5e-60 203.3 29.8 3.5e-60 203.3 20.7 1.3 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 KFM11347.1 - 0.012 14.7 35.8 0.0046 16.0 22.1 1.9 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Yae1_N PF09811.4 KFM11350.1 - 5.4e-17 61.0 52.6 1.5e+04 -10.9 36.5 4.9 1 1 0 1 1 1 0 Essential protein Yae1, N terminal zf-H2C2_2 PF13465.1 KFM11351.1 - 2.3e-48 160.2 131.0 1.2e-07 31.6 0.1 20.7 20 1 0 20 20 20 14 Zinc-finger double domain zf-C2H2 PF00096.21 KFM11351.1 - 1.4e-37 125.7 150.7 0.00016 21.8 2.3 18.4 18 0 0 18 18 18 15 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM11351.1 - 3.9e-36 120.7 134.7 0.0013 18.9 0.3 18.4 18 0 0 18 18 18 17 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KFM11351.1 - 1.1e-19 69.3 118.2 0.002 18.2 0.4 15.4 15 1 0 15 15 15 9 C2H2-type zinc-finger domain zf-Di19 PF05605.7 KFM11351.1 - 1.6e-10 40.9 93.5 0.0037 17.3 0.2 11.6 8 3 5 13 13 13 8 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 KFM11351.1 - 4.8e-07 29.7 86.1 0.012 15.7 0.2 14.0 14 0 0 14 14 14 6 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KFM11351.1 - 9.7e-05 22.4 5.7 9.7e-05 22.4 3.9 14.2 3 2 11 14 14 14 4 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KFM11351.1 - 0.034 14.3 0.5 0.034 14.3 0.3 15.0 18 0 0 18 18 18 0 Zinc-finger double-stranded RNA-binding Rad50_zn_hook PF04423.9 KFM11351.1 - 0.078 12.4 11.9 0.26 10.7 0.1 4.7 5 0 0 5 5 5 0 Rad50 zinc hook motif zf-C2H2_6 PF13912.1 KFM11351.1 - 0.93 9.4 0.0 0.33 10.9 0.9 11.5 13 0 0 13 13 13 0 C2H2-type zinc finger TPR_11 PF13414.1 KFM11353.1 - 5.8e-39 131.5 30.2 8.8e-10 38.0 2.0 5.4 2 1 3 6 6 6 6 TPR repeat TPR_1 PF00515.23 KFM11353.1 - 2.9e-38 127.9 26.8 3.7e-06 26.3 0.4 9.7 8 1 2 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.12 KFM11353.1 - 5.2e-34 113.4 23.0 5.5e-05 22.7 0.0 9.5 9 0 0 9 9 9 7 Tetratricopeptide repeat DUF1736 PF08409.6 KFM11353.1 - 3.6e-32 109.7 2.1 1.5e-31 107.7 1.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1736) TPR_12 PF13424.1 KFM11353.1 - 1.8e-30 104.7 25.9 2.2e-10 40.3 0.0 5.6 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.1 KFM11353.1 - 9.4e-24 81.3 21.1 0.00062 19.3 0.0 8.9 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.1 KFM11353.1 - 1.7e-20 73.1 10.2 0.00061 20.3 2.1 6.3 2 2 1 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 KFM11353.1 - 4.1e-19 67.1 19.0 0.0044 17.1 0.2 9.7 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_7 PF13176.1 KFM11353.1 - 3.3e-14 51.4 15.6 0.0058 16.3 0.0 8.5 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFM11353.1 - 1.7e-13 50.7 11.9 0.0072 16.6 0.8 5.3 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 KFM11353.1 - 3.8e-13 48.7 9.3 0.51 11.1 0.0 8.7 3 3 7 10 10 10 3 Tetratricopeptide repeat TPR_10 PF13374.1 KFM11353.1 - 8.5e-11 41.4 21.4 0.045 13.6 0.0 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat Apc3 PF12895.2 KFM11353.1 - 2.7e-09 37.0 12.9 0.00054 20.0 1.0 4.0 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 PMT_2 PF13231.1 KFM11353.1 - 1.6e-07 31.3 5.8 1.6e-07 31.3 4.0 2.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase TPR_6 PF13174.1 KFM11353.1 - 1.6e-07 31.3 14.0 0.083 13.3 0.0 7.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_3 PF07720.7 KFM11353.1 - 1.8e-07 30.8 10.0 0.19 11.5 0.1 5.8 7 0 0 7 7 6 3 Tetratricopeptide repeat NARP1 PF12569.3 KFM11353.1 - 2.6e-07 29.8 2.4 0.027 13.2 0.5 3.2 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_9 PF13371.1 KFM11353.1 - 3.9e-07 29.8 0.9 0.35 10.7 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.9 KFM11353.1 - 2.2e-06 27.5 0.0 10 6.9 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat PMT PF02366.13 KFM11353.1 - 7.8e-06 25.4 7.5 7.8e-06 25.4 5.2 2.0 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Coatomer_E PF04733.9 KFM11353.1 - 0.0014 17.8 2.5 1.6 7.8 0.2 3.2 2 1 0 3 3 3 2 Coatomer epsilon subunit FAT PF02259.18 KFM11353.1 - 0.0028 16.7 1.2 0.036 13.0 0.2 2.3 1 1 0 2 2 2 1 FAT domain Keratin_assoc PF09775.4 KFM11353.1 - 0.038 13.5 0.1 0.12 11.9 0.1 1.8 1 0 0 1 1 1 0 Keratinocyte-associated protein 2 Sel1 PF08238.7 KFM11353.1 - 0.039 14.6 17.1 21 5.9 0.1 7.2 8 0 0 8 8 6 0 Sel1 repeat TPR_15 PF13429.1 KFM11353.1 - 0.048 12.7 0.2 0.048 12.7 0.1 3.4 2 2 0 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.4 KFM11353.1 - 0.057 13.3 0.6 23 4.8 0.0 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 KFM11353.1 - 5.5 6.9 14.7 1.1 9.1 0.0 4.8 7 0 0 7 7 4 0 MIT (microtubule interacting and transport) domain Methyltransf_32 PF13679.1 KFM11354.1 - 6.6e-29 100.4 7.1 6.2e-28 97.2 4.9 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFM11354.1 - 2.2e-05 24.1 0.0 6.7e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFM11354.1 - 0.0002 21.1 0.0 0.0021 17.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFM11354.1 - 0.00026 21.5 0.0 0.00062 20.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFM11354.1 - 0.003 18.0 0.0 0.014 15.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFM11354.1 - 0.0072 16.7 0.0 0.018 15.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain NapE PF06796.6 KFM11354.1 - 0.059 12.6 0.0 0.26 10.6 0.0 2.1 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE MTS PF05175.9 KFM11354.1 - 0.075 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain MetW PF07021.7 KFM11354.1 - 0.09 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PCMT PF01135.14 KFM11354.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) rRNA_processing PF08524.6 KFM11356.1 - 6.5e-05 22.7 26.3 6.5e-05 22.7 18.2 2.1 1 1 1 2 2 2 1 rRNA processing MRP-S31 PF15433.1 KFM11356.1 - 0.31 10.4 17.3 0.36 10.2 12.0 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Toxin_64 PF15542.1 KFM11356.1 - 1.2 9.7 9.7 0.13 12.8 0.9 2.4 1 1 1 2 2 2 0 Putative toxin 64 DUF4544 PF15077.1 KFM11356.1 - 1.4 8.3 11.1 3.3 7.1 7.4 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4544) Glyco_hydro_4C PF11975.3 KFM11356.1 - 2.3 7.9 10.3 2.9 7.6 7.1 1.2 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain XPG_I_2 PF12813.2 KFM11356.1 - 2.7 7.4 8.8 3.2 7.1 6.1 1.0 1 0 0 1 1 1 0 XPG domain containing RR_TM4-6 PF06459.7 KFM11356.1 - 8.6 6.1 15.9 9.8 5.9 11.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.2 KFM11356.1 - 8.6 3.8 14.8 10 3.6 10.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4612 PF15389.1 KFM11356.1 - 9.1 6.9 15.1 18 5.9 10.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4612) AMP-binding PF00501.23 KFM11358.1 - 6.6e-87 291.5 0.0 7.8e-87 291.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFM11358.1 - 4.2e-16 59.6 0.7 1.4e-15 57.9 0.3 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PDZ PF00595.19 KFM11359.1 - 4e-21 74.9 0.4 6.5e-21 74.2 0.3 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) L27 PF02828.11 KFM11359.1 - 1.7e-17 62.8 0.1 3.2e-17 61.9 0.1 1.5 1 0 0 1 1 1 1 L27 domain PDZ_2 PF13180.1 KFM11359.1 - 6.3e-05 22.7 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain ECH PF00378.15 KFM11359.1 - 0.41 9.7 3.5 3.1 6.8 0.8 2.1 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase family fn3 PF00041.16 KFM11360.1 - 1.8e-177 575.9 67.0 1.7e-13 50.5 0.1 20.5 19 2 1 20 20 20 19 Fibronectin type III domain Y_phosphatase PF00102.22 KFM11360.1 - 1.1e-75 253.9 0.0 2.5e-75 252.8 0.0 1.7 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Interfer-bind PF09294.5 KFM11360.1 - 8.1e-13 48.3 6.9 0.44 10.5 0.0 12.1 14 0 0 14 14 14 2 Interferon-alpha/beta receptor, fibronectin type III Y_phosphatase3 PF13350.1 KFM11360.1 - 0.0003 21.0 0.1 0.00084 19.6 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KFM11360.1 - 0.029 14.4 0.0 0.068 13.2 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate DSPc PF00782.15 KFM11360.1 - 0.054 13.0 0.4 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Soyouz_module PF14313.1 KFM11360.1 - 0.28 10.7 1.5 0.52 9.9 0.4 1.9 2 0 0 2 2 2 0 N-terminal region of Paramyxovirinae phosphoprotein (P) fn3 PF00041.16 KFM11361.1 - 0.0075 16.3 0.6 0.052 13.6 0.4 1.9 1 1 0 1 1 1 1 Fibronectin type III domain VWD PF00094.20 KFM11362.1 - 1.1e-90 301.9 14.7 7.2e-26 91.2 0.2 4.7 4 0 0 4 4 4 4 von Willebrand factor type D domain C8 PF08742.6 KFM11362.1 - 5.5e-47 157.9 57.7 1.3e-17 63.7 9.0 9.5 10 0 0 10 10 10 4 C8 domain TIL PF01826.12 KFM11362.1 - 1.3e-13 50.8 71.2 5.4e-07 29.6 10.2 17.6 13 3 3 16 16 16 5 Trypsin Inhibitor like cysteine rich domain AbfB PF05270.8 KFM11362.1 - 1.3e-11 44.4 1.0 2.9e-11 43.2 0.4 1.9 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase B (ABFB) Yae1_N PF09811.4 KFM11363.1 - 7.4e-14 50.9 41.0 2e+03 -1.6 28.4 4.0 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Ribosomal_S9 PF00380.14 KFM11364.1 - 7.8e-36 122.9 0.2 8.8e-36 122.8 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Nckap1 PF09735.4 KFM11364.1 - 0.013 13.0 0.0 0.014 12.8 0.0 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein Ank PF00023.25 KFM11365.1 - 2.2e-31 106.0 1.4 8.2e-08 31.6 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_2 PF12796.2 KFM11365.1 - 6.3e-31 106.5 0.4 3.3e-14 52.9 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFM11365.1 - 2.4e-29 101.1 0.9 1.1e-12 48.1 0.0 3.9 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM11365.1 - 9.5e-27 92.4 4.3 9.4e-12 44.7 0.1 4.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM11365.1 - 3.1e-21 73.3 1.5 0.00038 20.4 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat C2 PF00168.25 KFM11366.1 - 6.5e-55 182.9 0.6 9.5e-27 92.6 0.2 2.2 2 0 0 2 2 2 2 C2 domain DUF1510 PF07423.6 KFM11366.1 - 0.0025 17.2 0.1 0.0069 15.7 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) DOCK-C2 PF14429.1 KFM11366.1 - 0.006 16.2 0.4 1.1 8.8 0.0 2.3 2 0 0 2 2 2 2 C2 domain in Dock180 and Zizimin proteins CEP76-C2 PF15627.1 KFM11366.1 - 0.02 14.4 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 CEP76 C2 domain Shisa PF13908.1 KFM11366.1 - 0.067 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator IncA PF04156.9 KFM11366.1 - 0.13 11.8 0.0 0.44 10.1 0.0 1.8 2 0 0 2 2 2 0 IncA protein Orthopox_F7 PF05813.7 KFM11366.1 - 0.52 10.2 4.7 1.2 9.0 2.6 2.2 2 0 0 2 2 2 0 Orthopoxvirus F7 protein CH PF00307.26 KFM11367.1 - 4.8e-14 52.3 0.4 1e-12 48.0 0.0 2.5 2 0 0 2 2 2 1 Calponin homology (CH) domain AAA_14 PF13173.1 KFM11367.1 - 5.9e-07 29.4 0.0 1.6e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KFM11367.1 - 1.2e-05 25.5 0.1 8.3e-05 22.7 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KFM11367.1 - 3.1e-05 24.1 0.0 0.00011 22.4 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KFM11367.1 - 9.2e-05 23.2 0.0 0.00028 21.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFM11367.1 - 0.00036 20.5 2.2 0.0032 17.4 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain CAMSAP_CH PF11971.3 KFM11367.1 - 0.00068 19.2 0.2 0.0076 15.8 0.0 2.6 2 0 0 2 2 2 1 CAMSAP CH domain AAA_18 PF13238.1 KFM11367.1 - 0.00074 19.8 0.0 0.0022 18.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KFM11367.1 - 0.0012 18.9 0.0 0.0063 16.6 0.0 2.3 2 0 0 2 2 2 1 RNA helicase PhoH PF02562.11 KFM11367.1 - 0.0014 17.9 0.0 0.003 16.8 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein AAA_19 PF13245.1 KFM11367.1 - 0.0021 17.7 0.0 0.0061 16.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 KFM11367.1 - 0.0028 17.1 0.0 0.0063 15.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 KFM11367.1 - 0.02 14.5 0.0 0.06 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 KFM11367.1 - 0.029 14.3 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain DivIC PF04977.10 KFM11367.1 - 0.59 9.6 13.1 2.5 7.6 0.2 4.4 4 0 0 4 4 4 0 Septum formation initiator FlaC_arch PF05377.6 KFM11367.1 - 1 9.3 3.9 6.6 6.7 0.3 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) HrpB7 PF09486.5 KFM11367.1 - 1.8 8.4 12.5 0.098 12.5 4.1 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) E2F_TDP PF02319.15 KFM11368.1 - 4.8e-45 150.9 1.1 1.7e-21 75.5 0.3 2.5 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.14 KFM11368.1 - 0.0001 21.9 0.1 0.0011 18.6 0.0 2.4 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.7 KFM11368.1 - 0.00044 20.0 0.0 0.43 10.4 0.0 2.4 2 0 0 2 2 2 2 B-block binding subunit of TFIIIC Cdc6_C PF09079.6 KFM11368.1 - 0.17 11.6 0.1 10 5.9 0.0 2.3 2 0 0 2 2 2 0 CDC6, C terminal Aminotran_5 PF00266.14 KFM11369.1 - 5.4e-47 160.3 0.0 7.5e-47 159.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V EamA PF00892.15 KFM11370.1 - 4.1e-16 59.1 25.0 9.2e-09 35.4 9.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 KFM11370.1 - 0.0033 16.4 18.6 0.0066 15.4 12.7 1.6 1 1 0 1 1 1 1 UAA transporter family LGFP PF08310.6 KFM11370.1 - 0.013 15.1 0.0 0.21 11.2 0.0 2.3 2 0 0 2 2 2 0 LGFP repeat STAG PF08514.6 KFM11371.1 - 1.1e-47 160.5 0.1 4e-47 158.7 0.1 2.0 1 0 0 1 1 1 1 STAG domain Carboxyl_trans PF01039.17 KFM11372.1 - 1.2e-189 630.8 0.0 1.4e-189 630.5 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 KFM11372.1 - 0.012 14.8 0.1 0.088 12.0 0.0 2.2 2 1 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) EF-hand_7 PF13499.1 KFM11374.1 - 1.5e-20 73.0 1.0 5.4e-17 61.6 0.9 3.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 KFM11374.1 - 1.6e-05 23.8 0.2 0.036 13.3 0.0 4.4 5 0 0 5 5 5 1 EF hand EF-hand_6 PF13405.1 KFM11374.1 - 2.3e-05 23.8 0.5 0.16 11.9 0.0 4.5 4 0 0 4 4 4 1 EF-hand domain EF-hand_5 PF13202.1 KFM11374.1 - 4e-05 22.7 0.0 0.0013 17.9 0.0 2.8 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KFM11374.1 - 0.00077 19.0 0.2 2.5 7.7 0.0 4.0 3 0 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFM11374.1 - 0.021 14.8 1.2 7.7 6.5 0.0 2.7 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DBR1 PF05011.8 KFM11375.1 - 3.1e-39 134.1 0.9 5.8e-39 133.2 0.6 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 KFM11375.1 - 7.5e-11 41.8 1.0 1.3e-10 41.0 0.7 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Adaptin_binding PF10199.4 KFM11375.1 - 0.0074 16.5 1.6 0.055 13.7 1.1 2.4 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Arm PF00514.18 KFM11376.1 - 4.4e-20 70.7 24.0 6.9e-05 22.5 0.1 11.0 12 0 0 12 12 12 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFM11376.1 - 5e-18 65.1 0.7 0.0058 16.8 0.0 7.5 3 2 5 8 8 8 5 HEAT repeats HEAT PF02985.17 KFM11376.1 - 2.5e-11 42.6 13.1 0.042 13.9 0.0 8.5 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.1 KFM11376.1 - 4.5e-06 26.9 2.0 9.3 6.8 0.0 6.8 5 2 2 7 7 7 2 HEAT-like repeat V-ATPase_H_C PF11698.3 KFM11376.1 - 9.1e-05 22.3 8.2 2.3 8.1 0.0 5.3 3 1 1 5 5 5 2 V-ATPase subunit H ParcG PF10274.4 KFM11376.1 - 0.028 14.3 3.4 0.7 9.7 0.2 3.6 2 1 0 3 3 3 0 Parkin co-regulated protein Thioredoxin PF00085.15 KFM11377.1 - 1.2e-07 31.3 0.0 1.3e-07 31.2 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Vps8 PF12816.2 KFM11378.1 - 5.5e-61 205.2 8.1 1.1e-58 197.6 0.7 3.2 3 0 0 3 3 3 2 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 KFM11378.1 - 1.5e-06 27.8 6.7 0.00086 18.9 0.2 3.7 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 KFM11378.1 - 0.00032 20.4 8.0 0.001 18.8 5.5 2.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFM11378.1 - 0.034 14.1 5.8 0.14 12.2 4.1 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM11378.1 - 2.2 8.0 8.8 6.7 6.5 6.1 1.9 1 0 0 1 1 1 0 zinc-RING finger domain 3HCDH_N PF02737.13 KFM11381.1 - 9.7e-52 175.2 0.4 1.3e-51 174.7 0.3 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KFM11381.1 - 1.6e-28 98.9 0.0 3.6e-25 88.1 0.0 2.9 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KFM11381.1 - 0.00096 19.0 0.1 0.0024 17.7 0.1 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KFM11381.1 - 0.0019 18.6 0.1 0.0047 17.3 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 KFM11381.1 - 0.0047 16.9 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain SAMP PF05924.6 KFM11381.1 - 0.23 10.6 0.9 1.8 7.8 0.4 2.3 2 0 0 2 2 2 0 SAMP Motif ECH PF00378.15 KFM11382.1 - 2e-57 194.1 0.5 2.1e-57 194.0 0.3 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 KFM11382.1 - 4.5e-05 23.2 0.0 0.26 11.0 0.0 2.1 2 0 0 2 2 2 2 Peptidase family S49 Pkinase_Tyr PF07714.12 KFM11383.1 - 1.8e-64 217.3 0.0 2.7e-64 216.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM11383.1 - 5e-60 202.8 0.0 9.2e-60 201.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HAUS-augmin3 PF14932.1 KFM11383.1 - 0.01 15.0 2.0 0.03 13.5 1.4 1.7 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Kinase-like PF14531.1 KFM11383.1 - 0.02 13.8 0.0 0.044 12.7 0.0 1.6 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KFM11383.1 - 0.039 13.6 0.0 1.4 8.5 0.0 3.1 3 0 0 3 3 3 0 Phosphotransferase enzyme family IFT57 PF10498.4 KFM11383.1 - 0.18 10.5 5.5 0.067 11.9 1.8 1.7 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 SNARE_assoc PF09335.6 KFM11385.1 - 2.8e-17 63.0 7.0 2.8e-17 63.0 4.8 1.4 2 0 0 2 2 2 1 SNARE associated Golgi protein Lipase PF00151.14 KFM11386.1 - 6.7e-80 268.7 0.0 9.5e-80 268.2 0.0 1.2 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.2 KFM11386.1 - 7.8e-05 22.6 0.1 0.00012 22.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Apc13p PF05839.6 KFM11387.1 - 3e-20 71.9 0.3 4.1e-20 71.5 0.2 1.2 1 0 0 1 1 1 1 Apc13p protein Transglut_core PF01841.14 KFM11389.1 - 2.1e-15 56.9 0.0 3.8e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.7 KFM11389.1 - 0.00011 21.4 0.1 0.00054 19.2 0.1 2.1 1 1 0 1 1 1 1 Transglutaminase-like domain Pkinase_Tyr PF07714.12 KFM11390.1 - 5.2e-99 330.5 0.0 6e-99 330.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM11390.1 - 2.4e-50 171.1 0.0 2.9e-50 170.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.1 KFM11390.1 - 3.2e-14 53.0 1.1 5.6e-14 52.3 0.8 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain ABC1 PF03109.11 KFM11390.1 - 0.062 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 ABC1 family Gb3_synth PF04572.7 KFM11391.1 - 1.2e-44 151.2 1.6 1.8e-44 150.6 1.1 1.2 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region Gly_transf_sug PF04488.10 KFM11391.1 - 9.4e-20 70.9 0.0 2.6e-19 69.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KFM11391.1 - 0.053 12.0 0.0 0.074 11.5 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain PMP22_Claudin PF00822.15 KFM11392.1 - 5e-31 107.5 14.3 6.6e-31 107.1 9.9 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFM11392.1 - 8.2e-16 58.1 11.1 1.3e-15 57.5 7.7 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF308 PF03729.8 KFM11392.1 - 0.0008 19.3 15.2 0.024 14.6 5.5 3.0 3 0 0 3 3 3 2 Short repeat of unknown function (DUF308) Amastin PF07344.6 KFM11392.1 - 0.037 13.6 11.8 0.027 14.0 6.7 1.8 1 1 0 1 1 1 0 Amastin surface glycoprotein DoxX PF07681.7 KFM11392.1 - 0.091 13.1 6.5 0.15 12.4 1.1 2.3 2 0 0 2 2 2 0 DoxX Trp_oprn_chp PF09534.5 KFM11392.1 - 1.2 8.7 5.0 11 5.5 3.4 2.4 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF1469 PF07332.6 KFM11392.1 - 2.3 7.9 21.1 0.15 11.7 5.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1469) TMEM171 PF15471.1 KFM11392.1 - 4.4 6.0 6.8 8.8 5.0 4.7 1.6 1 1 0 1 1 1 0 Transmembrane protein family 171 HMG_box PF00505.14 KFM11393.1 - 1.1e-26 92.8 4.3 1.1e-26 92.8 3.0 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFM11393.1 - 3e-11 43.5 2.5 5.1e-11 42.7 1.7 1.4 1 0 0 1 1 1 1 HMG-box domain SOXp PF12336.3 KFM11393.1 - 9.5e-06 26.1 1.9 7.5e-05 23.2 0.2 2.6 2 1 0 2 2 2 1 SOX transcription factor TBCC PF07986.7 KFM11395.1 - 5.1e-37 125.9 0.2 1e-36 124.9 0.2 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.6 KFM11395.1 - 3e-06 26.6 1.0 5.4e-06 25.8 0.7 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal CTDII PF01556.13 KFM11396.1 - 3.4e-30 103.7 3.6 1.2e-25 89.1 0.1 3.5 4 0 0 4 4 4 2 DnaJ C terminal domain DnaJ PF00226.26 KFM11396.1 - 7.1e-21 73.7 1.1 1.1e-20 73.1 0.7 1.3 1 0 0 1 1 1 1 DnaJ domain MHC_I PF00129.13 KFM11397.1 - 0.00018 20.8 0.0 0.00024 20.5 0.0 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 PFK PF00365.15 KFM11398.1 - 1.3e-191 634.6 9.1 1.5e-130 434.2 2.3 2.1 2 0 0 2 2 2 2 Phosphofructokinase LRR_4 PF12799.2 KFM11399.1 - 3.5e-14 52.0 15.2 1.8e-08 33.8 3.0 3.3 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM11399.1 - 2e-09 37.0 17.3 3.4e-06 26.7 2.9 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_9 PF14580.1 KFM11399.1 - 2.6e-06 27.0 0.0 4.5e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Leucine-rich repeat SART-1 PF03343.8 KFM11399.1 - 1.8e-05 23.3 0.3 2.3e-05 22.9 0.2 1.2 1 0 0 1 1 1 1 SART-1 family LRR_6 PF13516.1 KFM11399.1 - 0.00066 19.4 5.8 0.46 10.7 1.0 4.1 4 0 0 4 4 4 1 Leucine Rich repeat Arg_repressor PF01316.16 KFM11399.1 - 0.016 14.7 1.2 0.032 13.7 0.1 2.1 2 1 0 2 2 2 0 Arginine repressor, DNA binding domain LRR_7 PF13504.1 KFM11399.1 - 0.024 14.7 3.4 3.5 8.2 0.5 3.7 3 0 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.28 KFM11399.1 - 0.043 13.8 8.5 1.5 9.1 1.3 3.8 3 1 0 3 3 3 0 Leucine Rich Repeat RRM_1 PF00076.17 KFM11400.1 - 1.6e-22 78.9 0.0 2.2e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM11400.1 - 3.4e-17 62.1 0.0 5.1e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM11400.1 - 7.1e-13 48.1 0.0 1e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFM11400.1 - 0.026 14.3 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif MIP-T3 PF10243.4 KFM11400.1 - 0.35 9.2 7.4 0.37 9.2 5.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF566 PF04484.7 KFM11400.1 - 3.1 7.2 15.4 3.2 7.1 10.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) KH_1 PF00013.24 KFM11401.1 - 3.1e-56 186.8 12.5 1.3e-14 53.5 0.1 4.5 4 0 0 4 4 4 4 KH domain KH_3 PF13014.1 KFM11401.1 - 4.6e-38 128.2 15.6 1.2e-09 37.6 0.2 5.2 5 0 0 5 5 5 4 KH domain KH_2 PF07650.12 KFM11401.1 - 6.6e-17 60.8 10.4 0.00029 20.3 0.1 4.8 4 0 0 4 4 4 4 KH domain KH_4 PF13083.1 KFM11401.1 - 2.1e-16 59.3 1.3 0.0012 18.4 0.0 5.1 5 0 0 5 5 5 4 KH domain RRM_1 PF00076.17 KFM11401.1 - 2.4e-08 33.4 0.0 5.5e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_5 PF13184.1 KFM11401.1 - 4e-07 29.7 4.1 0.27 11.0 0.0 4.5 4 0 0 4 4 4 3 NusA-like KH domain RRM_5 PF13893.1 KFM11401.1 - 2.1e-06 27.4 0.1 4.7e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM11401.1 - 1.2e-05 25.1 0.0 4.7e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Peptidase_C48 PF02902.14 KFM11402.1 - 8.5e-45 153.0 0.5 1.1e-44 152.7 0.3 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C57 PF03290.8 KFM11402.1 - 0.00033 19.2 0.1 0.039 12.4 0.0 2.2 1 1 0 2 2 2 2 Vaccinia virus I7 processing peptidase Angiomotin_C PF12240.3 KFM11403.1 - 8.7e-95 316.0 10.2 8.7e-95 316.0 7.1 3.2 2 1 0 2 2 2 1 Angiomotin C terminal HALZ PF02183.13 KFM11403.1 - 0.0044 16.6 1.9 0.0044 16.6 1.3 5.2 6 0 0 6 6 6 1 Homeobox associated leucine zipper Tht1 PF04163.7 KFM11403.1 - 0.14 10.5 5.8 0.21 9.9 4.0 1.2 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein Pkinase_Tyr PF07714.12 KFM11404.1 - 1.7e-79 266.5 0.0 2.3e-79 266.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM11404.1 - 1.6e-31 109.4 0.2 2.7e-31 108.6 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain WIF PF02019.13 KFM11404.1 - 1.3e-16 60.2 0.2 2.8e-16 59.1 0.1 1.6 1 0 0 1 1 1 1 WIF domain Shisa PF13908.1 KFM11404.1 - 0.0018 18.4 0.3 0.003 17.7 0.2 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Gal-3-0_sulfotr PF06990.6 KFM11405.1 - 4.6e-122 407.5 0.5 5.2e-122 407.3 0.3 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.9 KFM11405.1 - 5.2e-05 23.0 0.2 0.00021 21.0 0.1 2.0 2 0 0 2 2 2 1 Sulfotransferase family DUF4080 PF13311.1 KFM11405.1 - 0.12 12.4 2.4 0.22 11.5 0.7 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF4080) MIP PF00230.15 KFM11406.1 - 5.5e-08 32.5 6.8 8e-08 32.0 4.7 1.2 1 0 0 1 1 1 1 Major intrinsic protein Pkinase PF00069.20 KFM11407.1 - 4.7e-73 245.5 0.0 7.5e-73 244.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM11407.1 - 9.9e-48 162.4 0.0 1.7e-47 161.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 KFM11407.1 - 7.4e-24 83.9 0.0 2e-23 82.5 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 KFM11407.1 - 4.6e-09 35.6 0.0 0.00014 20.9 0.0 2.2 1 1 0 2 2 2 2 Kinase-like APH PF01636.18 KFM11407.1 - 0.00078 19.2 0.0 0.0091 15.7 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KFM11407.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PIG-X PF08320.7 KFM11408.1 - 3e-36 124.6 0.0 3.4e-36 124.4 0.0 1.0 1 0 0 1 1 1 1 PIG-X / PBN1 CEP19 PF14933.1 KFM11409.1 - 2.7e-33 115.5 1.4 2.9e-33 115.4 1.0 1.0 1 0 0 1 1 1 1 CEP19-like protein LRR_8 PF13855.1 KFM11410.1 - 2.5e-44 148.8 55.3 8.1e-09 35.1 0.9 9.9 5 4 5 10 10 10 10 Leucine rich repeat LRR_4 PF12799.2 KFM11410.1 - 6.2e-36 121.4 54.3 5.7e-05 22.6 0.4 12.8 7 4 7 14 14 14 13 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM11410.1 - 1.3e-20 70.2 57.2 0.041 13.9 0.1 19.0 20 2 1 21 21 21 7 Leucine Rich Repeat LRR_6 PF13516.1 KFM11410.1 - 1.9e-10 39.6 52.3 1.8 8.8 0.2 16.8 18 0 0 18 18 18 5 Leucine Rich repeat LRR_7 PF13504.1 KFM11410.1 - 7.2e-09 34.4 60.2 0.55 10.6 0.1 17.0 17 1 1 18 18 18 4 Leucine rich repeat LRR_5 PF13306.1 KFM11410.1 - 0.00047 19.8 0.0 0.2 11.3 0.1 4.0 5 0 0 5 5 5 1 Leucine rich repeats (6 copies) LRR_9 PF14580.1 KFM11410.1 - 0.0048 16.4 8.8 1.7 8.1 0.0 4.6 1 1 3 5 5 5 3 Leucine-rich repeat WD40 PF00400.27 KFM11411.1 - 4.4e-22 77.0 0.1 1.5e-05 24.6 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat zf-C3HC4_2 PF13923.1 KFM11412.1 - 1.3e-06 28.2 14.5 3.3e-06 27.0 10.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM11412.1 - 2.8e-06 26.8 14.7 2.8e-06 26.8 10.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM11412.1 - 4.4e-06 26.2 13.6 4.4e-06 26.2 9.4 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM11412.1 - 1.1e-05 25.0 12.6 2.8e-05 23.7 8.8 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFM11412.1 - 0.00011 22.0 17.6 0.00013 21.7 11.0 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KFM11412.1 - 0.0006 19.5 16.9 0.0013 18.4 11.7 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.1 KFM11412.1 - 0.0022 17.5 8.8 0.0069 15.9 6.1 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 KFM11412.1 - 0.0041 16.8 10.2 0.02 14.6 7.1 2.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 KFM11412.1 - 1.3 8.6 14.6 4.6 6.9 9.1 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain UBX PF00789.15 KFM11413.1 - 5e-19 68.1 0.0 9.3e-19 67.2 0.0 1.5 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.1 KFM11413.1 - 1.3e-12 47.5 0.1 2.2e-12 46.8 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.1 KFM11413.1 - 3.5e-10 39.2 0.1 1e-08 34.5 0.0 2.6 2 0 0 2 2 2 1 UBA-like domain Thioredox_DsbH PF03190.10 KFM11413.1 - 0.02 14.6 0.3 0.035 13.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 UBA PF00627.26 KFM11413.1 - 0.035 13.9 0.0 0.32 10.8 0.0 2.3 2 0 0 2 2 2 0 UBA/TS-N domain L6_membrane PF05805.7 KFM11414.1 - 3.3e-54 183.4 7.9 3.8e-54 183.2 5.5 1.0 1 0 0 1 1 1 1 L6 membrane protein BNR_2 PF13088.1 KFM11415.1 - 8e-30 104.0 0.0 1.2e-25 90.3 0.0 2.1 2 0 0 2 2 2 2 BNR repeat-like domain BNR_3 PF13859.1 KFM11415.1 - 1.9e-05 23.8 0.0 2.4e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.15 KFM11415.1 - 0.0067 16.0 1.9 12 6.2 0.0 3.9 3 0 0 3 3 3 2 BNR/Asp-box repeat Gal-3-0_sulfotr PF06990.6 KFM11416.1 - 1.3e-133 445.6 6.1 1.4e-133 445.4 4.2 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.9 KFM11416.1 - 0.00068 19.3 0.1 0.0014 18.3 0.1 1.5 1 0 0 1 1 1 1 Sulfotransferase family ING PF12998.2 KFM11417.1 - 1.9e-28 98.8 1.4 2.8e-28 98.2 0.9 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 KFM11417.1 - 5.2e-10 38.8 8.3 1e-09 37.9 5.8 1.5 1 0 0 1 1 1 1 PHD-finger RRF PF01765.14 KFM11417.1 - 0.0016 17.9 2.6 0.0022 17.4 1.8 1.2 1 0 0 1 1 1 1 Ribosome recycling factor zf-RING-like PF08746.6 KFM11417.1 - 0.017 15.1 5.3 0.031 14.2 3.7 1.5 1 0 0 1 1 1 0 RING-like domain zf-HC5HC2H PF13771.1 KFM11417.1 - 0.021 14.9 0.5 0.064 13.4 0.3 1.8 1 0 0 1 1 1 0 PHD-like zinc-binding domain DUF4200 PF13863.1 KFM11417.1 - 3.2 7.7 9.2 4.9 7.1 6.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Thymidylate_kin PF02223.12 KFM11418.1 - 6.2e-39 133.2 0.0 7.8e-39 132.9 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase Peptidase_C54 PF03416.14 KFM11419.1 - 1.9e-107 358.5 0.0 2.4e-107 358.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 PI3K_p85B PF02192.11 KFM11419.1 - 0.07 12.5 0.0 0.28 10.6 0.0 2.0 2 0 0 2 2 2 0 PI3-kinase family, p85-binding domain THAP PF05485.7 KFM11420.1 - 3e-15 56.1 0.7 8.8e-15 54.6 0.5 1.8 1 0 0 1 1 1 1 THAP domain DUF1794 PF08768.6 KFM11420.1 - 3.8e-11 43.0 0.0 7.2e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) DUF4201 PF13870.1 KFM11420.1 - 0.0058 16.0 0.6 0.012 15.1 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) HrpB7 PF09486.5 KFM11420.1 - 0.0093 15.9 0.6 0.07 13.0 0.2 2.1 2 0 0 2 2 2 1 Bacterial type III secretion protein (HrpB7) Atg14 PF10186.4 KFM11420.1 - 0.013 14.4 0.8 0.023 13.6 0.5 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DivIC PF04977.10 KFM11420.1 - 1.1 8.8 4.7 0.35 10.3 0.2 2.1 2 0 0 2 2 2 0 Septum formation initiator Sema PF01403.14 KFM11421.1 - 1.6e-142 475.0 0.2 2.6e-142 474.3 0.2 1.3 1 0 0 1 1 1 1 Sema domain PSI PF01437.20 KFM11421.1 - 5.6e-08 32.8 2.6 1.3e-07 31.6 1.8 1.6 1 0 0 1 1 1 1 Plexin repeat HCaRG PF07258.9 KFM11422.1 - 1.1e-25 90.1 6.0 1.3e-25 90.0 4.2 1.0 1 0 0 1 1 1 1 HCaRG protein ARF7EP_C PF14949.1 KFM11423.1 - 1.7e-33 115.1 11.4 1.9e-33 115.0 7.9 1.0 1 0 0 1 1 1 1 ARF7 effector protein C-terminus Peptidase_M1 PF01433.15 KFM11424.1 - 2.3e-88 296.9 0.0 4.4e-88 295.9 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 KFM11424.1 - 3.6e-26 92.1 0.4 5.5e-26 91.5 0.3 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KFM11424.1 - 9.8e-12 45.0 0.0 2.9e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 Peptidase MA superfamily Clat_adaptor_s PF01217.15 KFM11425.1 - 1.2e-41 141.7 2.9 1.4e-41 141.5 2.0 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain CDO_I PF05995.7 KFM11426.1 - 3.8e-47 159.7 0.1 4.3e-47 159.5 0.0 1.0 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 KFM11426.1 - 1.5e-05 24.4 0.3 3.1e-05 23.4 0.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1637) 2OG-FeII_Oxy_4 PF13661.1 KFM11426.1 - 0.028 14.0 0.2 0.06 12.9 0.1 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily EMP24_GP25L PF01105.19 KFM11427.1 - 2.8e-33 115.1 0.0 3.1e-33 115.0 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Occludin_ELL PF07303.8 KFM11428.1 - 8.7e-31 106.6 10.4 1.5e-30 105.9 7.2 1.4 1 0 0 1 1 1 1 Occludin homology domain MARVEL PF01284.18 KFM11428.1 - 5.4e-17 61.9 11.3 7.4e-17 61.5 7.8 1.2 1 0 0 1 1 1 1 Membrane-associating domain Tex_N PF09371.5 KFM11428.1 - 0.069 12.4 2.9 0.11 11.7 2.0 1.2 1 0 0 1 1 1 0 Tex-like protein N-terminal domain Seryl_tRNA_N PF02403.17 KFM11428.1 - 0.076 13.0 1.1 0.13 12.2 0.8 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF429 PF04250.8 KFM11428.1 - 0.3 10.3 2.2 0.37 10.0 0.3 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF429) Med9 PF07544.8 KFM11428.1 - 0.52 10.0 2.4 1.6 8.5 0.2 2.1 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Ssl1 PF04056.9 KFM11429.1 - 6.2e-89 296.7 0.1 8.7e-89 296.2 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.1 KFM11429.1 - 4e-14 53.0 0.0 5.8e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain C1_4 PF07975.7 KFM11429.1 - 9.2e-13 47.9 30.1 1.2e-12 47.6 15.4 2.6 2 0 0 2 2 2 2 TFIIH C1-like domain VWA PF00092.23 KFM11429.1 - 0.015 15.0 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain SMN PF06003.7 KFM11430.1 - 8.4e-123 408.6 12.3 1.3e-122 407.9 8.5 1.3 1 1 0 1 1 1 1 Survival motor neuron protein (SMN) TUDOR PF00567.19 KFM11430.1 - 0.00053 19.8 0.0 0.00087 19.1 0.0 1.3 1 0 0 1 1 1 1 Tudor domain ASXH PF13919.1 KFM11430.1 - 0.016 15.0 0.8 1.5 8.5 0.3 2.3 2 0 0 2 2 2 0 Asx homology domain 4F5 PF04419.9 KFM11431.1 - 3.2e-07 30.9 9.4 3.2e-07 30.9 6.5 2.1 2 0 0 2 2 2 1 4F5 protein family Toxin_39 PF15500.1 KFM11431.1 - 1.5 9.0 5.4 2.8 8.1 3.7 1.4 1 1 0 1 1 1 0 Putative RNase-like toxin Pox_Ag35 PF03286.9 KFM11432.1 - 4.9 6.6 22.8 4.6 6.7 2.4 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein RNA_pol_3_Rpc31 PF11705.3 KFM11432.1 - 5.5 6.8 26.9 7.7 6.3 8.6 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Carboxyl_trans PF01039.17 KFM11435.1 - 1.5e-158 528.2 0.0 1.8e-158 527.9 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 KFM11435.1 - 3.8e-05 22.9 0.1 0.13 11.3 0.0 2.3 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) PNP_UDP_1 PF01048.15 KFM11436.1 - 4.8e-49 166.4 0.0 5.4e-49 166.2 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily NLPC_P60 PF00877.14 KFM11436.1 - 0.021 14.6 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 NlpC/P60 family Aconitase PF00330.15 KFM11437.1 - 1.7e-135 452.1 0.0 2.1e-135 451.8 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KFM11437.1 - 1.1e-44 151.7 0.0 3.2e-43 146.9 0.0 2.3 2 0 0 2 2 2 1 Aconitase C-terminal domain DAGK_acc PF00609.14 KFM11438.1 - 1.2e-49 168.5 0.0 2.6e-49 167.4 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 KFM11438.1 - 1.3e-26 92.5 0.0 3e-26 91.4 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain RA PF00788.18 KFM11438.1 - 2.6e-19 69.5 1.3 1.1e-11 45.0 0.2 3.3 3 0 0 3 3 3 2 Ras association (RalGDS/AF-6) domain C1_1 PF00130.17 KFM11438.1 - 1.4e-15 56.7 42.0 3.6e-12 45.8 4.1 3.8 3 1 1 4 4 4 3 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_3 PF07649.7 KFM11438.1 - 0.0047 16.9 4.9 0.0047 16.9 3.4 4.0 4 1 0 4 4 4 2 C1-like domain zf-met PF12874.2 KFM11438.1 - 3.8 7.8 11.5 2.7 8.3 0.9 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Rhodanese PF00581.15 KFM11439.1 - 1.1e-08 35.4 0.0 2.5e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain MIF4G_like_2 PF09090.6 KFM11440.1 - 3.8e-74 249.1 3.2 7.7e-74 248.1 1.5 1.9 2 0 0 2 2 2 1 MIF4G like MIF4G_like PF09088.6 KFM11440.1 - 2.3e-57 193.5 3.3 3.3e-54 183.2 1.5 3.7 3 1 0 3 3 3 1 MIF4G like MIF4G PF02854.14 KFM11440.1 - 3.7e-25 88.5 2.7 5.8e-25 87.9 0.0 2.8 3 0 0 3 3 3 1 MIF4G domain Mnd1 PF03962.10 KFM11440.1 - 0.0086 15.7 0.8 0.02 14.5 0.5 1.6 1 0 0 1 1 1 1 Mnd1 family DUF4611 PF15387.1 KFM11440.1 - 0.022 14.8 0.7 0.022 14.8 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Vfa1 PF08432.5 KFM11440.1 - 0.31 11.0 5.1 0.6 10.1 3.5 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PBP1_TM PF14812.1 KFM11440.1 - 0.88 9.9 12.3 0.036 14.3 4.3 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FlxA PF14282.1 KFM11440.1 - 4.6 7.2 7.1 1.7 8.5 2.7 1.9 2 0 0 2 2 2 0 FlxA-like protein XPA_C PF05181.7 KFM11441.1 - 4.8e-29 99.6 0.9 5.3e-29 99.5 0.6 1.0 1 0 0 1 1 1 1 XPA protein C-terminus Kazal_1 PF00050.16 KFM11443.1 - 3.4e-17 62.2 6.5 2.5e-16 59.3 1.3 2.0 1 1 1 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 KFM11443.1 - 1.1e-12 47.6 1.1 1.1e-12 47.6 0.8 2.1 2 1 0 2 2 2 1 Kazal-type serine protease inhibitor domain Pertus-S5-tox PF09276.5 KFM11443.1 - 0.13 12.2 0.2 0.24 11.3 0.1 1.5 1 1 0 1 1 1 0 Pertussis toxin S5 subunit Glyco_transf_7N PF13733.1 KFM11444.1 - 4.8e-48 162.0 0.1 6.7e-48 161.5 0.1 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.9 KFM11444.1 - 4e-33 112.7 0.4 7.9e-33 111.7 0.3 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFM11444.1 - 2.1e-07 30.3 0.1 0.00017 20.7 0.0 2.2 1 1 1 2 2 2 2 Glycosyltransferase like family 2 WD40 PF00400.27 KFM11445.1 - 5.4e-47 156.0 12.9 5.9e-11 41.8 0.1 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 KFM11445.1 - 2.6e-10 39.0 1.3 1.7e-06 26.4 0.5 3.5 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KFM11445.1 - 9e-05 21.3 1.0 0.11 11.2 0.7 3.6 2 1 1 3 3 3 1 Nup133 N terminal like Hira PF07569.6 KFM11445.1 - 0.00035 19.8 0.2 1.3 8.1 0.0 3.8 3 1 1 4 4 4 1 TUP1-like enhancer of split LisH PF08513.6 KFM11445.1 - 0.015 15.0 0.1 0.035 13.8 0.0 1.7 1 0 0 1 1 1 0 LisH PD40 PF07676.7 KFM11445.1 - 0.078 12.6 0.0 3.6 7.3 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat CTDII PF01556.13 KFM11446.1 - 3.4e-23 81.3 0.5 9e-18 63.9 0.0 2.7 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KFM11446.1 - 2.2e-13 50.0 20.7 4e-13 49.2 14.4 1.5 1 0 0 1 1 1 1 DnaJ central domain DnaJ PF00226.26 KFM11446.1 - 1.8e-05 24.3 0.1 3.3e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain HypA PF01155.14 KFM11446.1 - 0.018 14.7 8.6 0.66 9.6 0.8 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Actin PF00022.14 KFM11447.1 - 1.6e-106 356.0 0.0 2e-106 355.7 0.0 1.1 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KFM11447.1 - 5.3e-06 25.2 0.0 4.7e-05 22.1 0.0 2.2 1 1 0 1 1 1 1 MreB/Mbl protein RabGAP-TBC PF00566.13 KFM11448.1 - 8.4e-53 179.0 2.0 8.4e-53 179.0 1.4 2.4 3 0 0 3 3 3 1 Rab-GTPase-TBC domain PH PF00169.24 KFM11448.1 - 1.3e-08 35.0 0.6 6.8e-08 32.6 0.0 2.2 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 KFM11448.1 - 9.6e-07 29.0 0.2 5.5e-06 26.6 0.1 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 KFM11448.1 - 0.00011 22.2 0.1 0.00032 20.7 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain MutS_III PF05192.13 KFM11448.1 - 0.016 15.0 0.1 0.23 11.2 0.0 2.5 1 1 0 1 1 1 0 MutS domain III Y_phosphatase3 PF13350.1 KFM11448.1 - 0.31 11.2 7.6 5.9 7.1 5.3 2.4 1 1 0 1 1 1 0 Tyrosine phosphatase family SlyX PF04102.7 KFM11448.1 - 0.65 10.4 22.3 1.3 9.4 4.2 4.0 3 0 0 3 3 3 0 SlyX DUF1900 PF08954.6 KFM11449.1 - 1.9e-52 176.4 0.0 4.9e-52 175.0 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 KFM11449.1 - 3.6e-32 109.7 0.2 6e-32 109.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 KFM11449.1 - 6.4e-25 86.0 3.3 5.3e-08 32.4 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat HAUS2 PF15003.1 KFM11449.1 - 0.0078 15.3 0.1 0.015 14.3 0.1 1.4 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 2 SGL PF08450.7 KFM11449.1 - 0.037 13.4 0.0 0.065 12.6 0.0 1.4 1 0 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region Saccharop_dh PF03435.13 KFM11449.1 - 0.14 11.1 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Yae1_N PF09811.4 KFM11450.1 - 3.3e-08 32.9 37.5 1.5e+04 -5.2 26.0 3.7 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Tetraspannin PF00335.15 KFM11451.1 - 1.1e-25 90.2 4.2 1.3e-25 90.0 2.9 1.0 1 0 0 1 1 1 1 Tetraspanin family SUR7 PF06687.7 KFM11451.1 - 0.053 13.0 3.4 2.2 7.8 1.3 2.2 2 1 0 2 2 2 0 SUR7/PalI family YfhO PF09586.5 KFM11451.1 - 0.16 9.9 4.0 0.21 9.5 2.8 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Glyco_hydro_31 PF01055.21 KFM11452.1 - 1.8e-250 831.1 10.2 3.3e-152 507.3 2.5 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 31 Trefoil PF00088.13 KFM11452.1 - 3e-12 45.9 18.8 2.9e-08 33.1 2.9 2.9 3 0 0 3 3 3 2 Trefoil (P-type) domain Gal_mutarotas_2 PF13802.1 KFM11452.1 - 2.4e-09 36.9 6.8 0.00041 20.1 1.2 2.8 2 0 0 2 2 2 2 Galactose mutarotase-like GHL15 PF14885.1 KFM11452.1 - 0.036 14.2 3.8 2.8 8.2 0.1 3.0 2 1 0 2 2 2 0 Hypothetical glycosyl hydrolase family 15 Y_phosphatase PF00102.22 KFM11455.1 - 5.2e-11 42.3 0.0 5.3e-09 35.7 0.0 2.0 1 1 1 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.15 KFM11455.1 - 1.9e-09 37.2 0.0 2.5e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain 7tm_1 PF00001.16 KFM11456.1 - 8.7e-34 116.8 33.7 2e-33 115.6 23.4 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) YWFCY PF14293.1 KFM11456.1 - 1 9.2 8.5 6.8 6.6 0.1 3.2 3 0 0 3 3 3 0 YWFCY protein MFS_1 PF07690.11 KFM11457.1 - 3.7e-16 58.7 17.3 5.5e-10 38.4 2.5 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 KFM11457.1 - 5.7e-07 28.2 1.0 5.7e-07 28.2 0.7 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein dDENN PF03455.14 KFM11458.1 - 4.3e-08 33.1 0.3 1.2e-07 31.7 0.2 1.8 1 0 0 1 1 1 1 dDENN domain bPH_3 PF14470.1 KFM11458.1 - 0.059 13.6 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 Bacterial PH domain uDENN PF03456.13 KFM11459.1 - 1.9e-06 27.7 0.0 4.2e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 uDENN domain DENN PF02141.16 KFM11459.1 - 0.047 13.4 0.1 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 DENN (AEX-3) domain Pkinase_Tyr PF07714.12 KFM11460.1 - 1.9e-87 292.6 0.0 3.1e-87 291.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Focal_AT PF03623.8 KFM11460.1 - 1.8e-65 218.6 3.5 3.9e-65 217.5 2.4 1.6 1 0 0 1 1 1 1 Focal adhesion targeting region Pkinase PF00069.20 KFM11460.1 - 3.5e-44 150.9 0.0 8.6e-44 149.6 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain FERM_M PF00373.13 KFM11460.1 - 5.4e-11 42.7 0.1 5.4e-11 42.7 0.1 2.3 2 1 0 2 2 2 1 FERM central domain Kinase-like PF14531.1 KFM11460.1 - 5.9e-05 22.1 0.0 0.00012 21.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like FERM_N PF09379.5 KFM11460.1 - 0.084 12.9 0.1 0.45 10.5 0.0 2.3 2 0 0 2 2 2 0 FERM N-terminal domain DUF4085 PF13315.1 KFM11460.1 - 0.37 10.1 7.3 0.78 9.0 0.2 3.0 3 1 0 4 4 4 0 Protein of unknown function (DUF4085) RVT_1 PF00078.22 KFM11462.1 - 7.6e-12 45.0 0.0 1.1e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3471 PF11954.3 KFM11462.1 - 0.14 11.9 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3471) CBFD_NFYB_HMF PF00808.18 KFM11463.1 - 7.4e-12 45.1 0.0 1.1e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TRAPPC9-Trs120 PF08626.6 KFM11464.1 - 7.1e-262 871.5 0.0 1.4e-261 870.5 0.0 1.5 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TRAPPC9-Trs120 PF08626.6 KFM11466.1 - 6e-08 30.5 0.0 6.9e-08 30.3 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Ion_trans_2 PF07885.11 KFM11467.1 - 2.2e-36 123.3 17.0 2.3e-19 68.8 0.2 2.9 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.26 KFM11467.1 - 0.00013 21.2 9.7 0.023 13.9 0.1 2.5 1 1 1 2 2 2 2 Ion transport protein CytochromB561_N PF09786.4 KFM11467.1 - 0.012 14.0 0.1 0.018 13.4 0.1 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal IRK PF01007.15 KFM11467.1 - 0.17 10.6 2.0 0.36 9.5 0.0 2.1 2 0 0 2 2 2 0 Inward rectifier potassium channel Collagen PF01391.13 KFM11470.1 - 2.7e-131 427.1 522.3 6.9e-09 35.1 23.1 17.2 3 3 11 14 14 14 13 Collagen triple helix repeat (20 copies) VWA PF00092.23 KFM11470.1 - 4.9e-48 163.2 0.1 6.5e-48 162.7 0.1 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 KFM11470.1 - 6.7e-18 65.3 0.0 9.3e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain Laminin_G_2 PF02210.19 KFM11470.1 - 0.0065 16.5 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_3 PF13385.1 KFM11470.1 - 0.039 14.1 0.0 0.07 13.3 0.0 1.3 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Brix PF04427.13 KFM11470.1 - 0.67 9.5 0.0 1.2 8.7 0.0 1.3 1 0 0 1 1 1 0 Brix domain DUF676 PF05057.9 KFM11471.1 - 1.1e-57 194.8 0.0 1.8e-57 194.1 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF3657 PF12394.3 KFM11471.1 - 1.6e-26 92.1 10.7 8.9e-18 64.1 0.8 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF3657) PGAP1 PF07819.8 KFM11471.1 - 2e-05 24.3 0.0 3.6e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.10 KFM11471.1 - 0.00056 18.9 0.0 0.001 18.1 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF1311 PF07007.7 KFM11475.1 - 0.23 11.5 2.7 10 6.2 0.4 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1311) TLV_coat PF00429.14 KFM11476.1 - 0.038 12.4 0.2 0.04 12.3 0.1 1.0 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) Radical_SAM PF04055.16 KFM11477.1 - 1.8e-20 73.7 0.1 7.2e-20 71.8 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily TRAM PF01938.15 KFM11477.1 - 6.9e-07 28.9 0.0 1.6e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 TRAM domain UPF0004 PF00919.15 KFM11477.1 - 5.8e-06 26.0 0.0 1.3e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Hormone_1 PF00103.15 KFM11481.1 - 3.3e-74 248.8 0.1 3.8e-74 248.6 0.0 1.0 1 0 0 1 1 1 1 Somatotropin hormone family KIAA1430 PF13879.1 KFM11481.1 - 0.12 12.8 0.0 2.8 8.4 0.0 2.2 2 0 0 2 2 2 0 KIAA1430 homologue Neurensin PF14927.1 KFM11482.1 - 6.1e-52 174.7 0.0 7.4e-52 174.4 0.0 1.1 1 0 0 1 1 1 1 Neurensin DUF624 PF04854.9 KFM11482.1 - 0.018 14.9 1.1 0.067 13.0 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF624 Claudin_2 PF13903.1 KFM11482.1 - 0.098 12.3 0.3 0.17 11.5 0.2 1.4 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction COX8 PF02285.10 KFM11482.1 - 0.23 11.0 1.0 0.46 10.0 0.7 1.5 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIII FG-GAP PF01839.18 KFM11484.1 - 2.3e-21 74.8 29.2 5.8e-07 29.0 1.0 5.4 5 0 0 5 5 5 4 FG-GAP repeat Zn_dep_PLPC PF00882.13 KFM11484.1 - 6.3e-20 71.4 1.9 1.4e-19 70.3 1.3 1.6 1 0 0 1 1 1 1 Zinc dependent phospholipase C VCBS PF13517.1 KFM11484.1 - 1.4e-14 54.1 12.2 4.7e-07 30.0 1.4 4.7 2 1 2 4 4 4 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.3 KFM11484.1 - 0.0001 21.8 0.2 0.058 12.8 0.0 3.1 2 1 1 3 3 3 2 Insecticide toxin TcdB middle/N-terminal region BBS2_Mid PF14783.1 KFM11484.1 - 0.041 13.6 0.0 25 4.7 0.0 4.1 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Aldedh PF00171.17 KFM11485.1 - 2.3e-152 507.5 1.4 2.5e-152 507.4 1.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family REJ PF02010.10 KFM11486.1 - 6.2e-22 77.5 10.1 3.8e-12 45.2 0.7 3.8 1 1 2 3 3 3 3 REJ domain Y_Y_Y PF07495.8 KFM11486.1 - 3.7e-17 61.8 0.0 0.0021 17.7 0.0 5.4 5 0 0 5 5 5 4 Y_Y_Y domain PKD PF00801.15 KFM11486.1 - 1.7e-12 46.8 8.6 0.012 15.3 0.1 5.7 5 0 0 5 5 5 4 PKD domain DUF4625 PF15418.1 KFM11486.1 - 5.6e-09 36.2 0.0 1.1 9.3 0.0 4.6 4 0 0 4 4 4 4 Domain of unknown function (DUF4625) He_PIG PF05345.7 KFM11486.1 - 1.4e-05 24.9 2.9 13 5.8 0.0 5.6 5 0 0 5 5 5 1 Putative Ig domain Big_3_4 PF13754.1 KFM11486.1 - 1.4e-05 25.2 12.0 0.37 11.1 0.0 5.8 5 0 0 5 5 5 1 Bacterial Ig-like domain (group 3) MANEC PF07502.9 KFM11486.1 - 0.0014 18.5 4.8 0.0052 16.7 3.3 1.9 1 0 0 1 1 1 1 MANEC domain Cadherin PF00028.12 KFM11486.1 - 0.0019 18.4 1.0 18 5.6 0.0 4.5 4 0 0 4 4 4 0 Cadherin domain SieB PF14163.1 KFM11486.1 - 0.068 12.7 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Superinfection exclusion protein B Arf PF00025.16 KFM11487.1 - 2.3e-62 209.2 0.0 2.6e-62 209.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KFM11487.1 - 1.5e-15 57.0 0.0 1.6e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KFM11487.1 - 4.7e-11 42.2 0.0 7e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KFM11487.1 - 2.4e-10 40.9 0.0 3.2e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 KFM11487.1 - 8e-08 31.3 0.1 1.9e-06 26.8 0.0 2.1 1 1 1 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.22 KFM11487.1 - 5.9e-06 25.8 0.0 2.8e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFM11487.1 - 9.9e-06 25.4 0.0 1.4e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFM11487.1 - 0.00081 18.6 0.0 0.001 18.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region 6PF2K PF01591.13 KFM11487.1 - 0.054 12.5 0.0 0.077 12.0 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase cobW PF02492.14 KFM11487.1 - 0.13 11.7 0.0 1 8.7 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Spp-24 PF07448.6 KFM11488.1 - 4.7e-22 78.4 0.3 6.8e-22 77.9 0.2 1.3 1 0 0 1 1 1 1 Secreted phosphoprotein 24 (Spp-24) Cathelicidins PF00666.12 KFM11488.1 - 4.4e-06 26.7 0.0 7.1e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Cathelicidin Cystatin PF00031.16 KFM11488.1 - 0.01 15.9 0.0 0.018 15.1 0.0 1.4 1 1 0 1 1 1 0 Cystatin domain Ion_trans PF00520.26 KFM11489.1 - 1.1e-11 44.4 18.6 1.1e-11 44.4 12.9 3.3 3 1 0 3 3 3 1 Ion transport protein ArfGap PF01412.13 KFM11490.1 - 1.1e-40 138.0 0.1 2.5e-40 136.9 0.0 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Miro PF08477.8 KFM11490.1 - 7.1e-23 81.3 0.0 1.7e-22 80.1 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 KFM11490.1 - 3.3e-18 65.5 0.0 6.1e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Ras family Ank_2 PF12796.2 KFM11490.1 - 4.3e-15 55.8 0.1 8.6e-15 54.8 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFM11490.1 - 1.6e-12 46.5 0.4 5.3e-08 32.2 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat PH PF00169.24 KFM11490.1 - 4.4e-10 39.6 2.2 2.1e-09 37.4 0.3 2.9 2 1 0 2 2 2 1 PH domain Ank_5 PF13857.1 KFM11490.1 - 7.8e-10 38.6 0.7 2.5e-09 37.0 0.4 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFM11490.1 - 8.5e-09 35.6 0.1 8.2e-07 29.3 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM11490.1 - 2.9e-06 26.9 0.0 6.7e-05 22.7 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat PH_11 PF15413.1 KFM11490.1 - 0.0036 17.5 1.8 0.57 10.4 0.0 3.1 3 0 0 3 3 2 1 Pleckstrin homology domain PH_6 PF15406.1 KFM11490.1 - 0.004 17.1 0.3 0.004 17.1 0.2 1.8 2 0 0 2 2 1 1 Pleckstrin homology domain PH_8 PF15409.1 KFM11490.1 - 0.057 13.4 0.6 5 7.2 0.1 2.9 3 0 0 3 3 3 0 Pleckstrin homology domain Chibby PF14645.1 KFM11490.1 - 1.2 9.0 4.7 0.25 11.2 0.6 1.8 2 0 0 2 2 1 0 Chibby family Pap_E4 PF02711.9 KFM11490.1 - 6 7.7 11.3 1.5 9.6 0.3 3.8 3 0 0 3 3 3 0 E4 protein AAA PF00004.24 KFM11491.1 - 1.1e-16 61.2 0.0 2.5e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IQ PF00612.22 KFM11491.1 - 1.2e-05 24.4 0.0 3.8e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif AAA_5 PF07728.9 KFM11491.1 - 0.042 13.5 0.3 0.5 10.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Hom_end_hint PF05203.11 KFM11491.1 - 6.1 6.5 7.6 0.76 9.4 1.9 1.9 2 0 0 2 2 2 0 Hom_end-associated Hint PCI_Csn8 PF10075.4 KFM11492.1 - 4.3e-36 123.8 0.0 5.6e-36 123.4 0.0 1.1 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 KFM11492.1 - 0.0024 17.4 0.0 0.0032 17.0 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI PF01399.22 KFM11492.1 - 0.018 15.3 0.0 0.028 14.7 0.0 1.3 1 0 0 1 1 1 0 PCI domain FYVE_2 PF02318.11 KFM11493.1 - 1.2e-49 167.0 13.6 1.2e-49 167.0 9.4 2.4 3 0 0 3 3 3 1 FYVE-type zinc finger Rab_eff_C PF04698.7 KFM11493.1 - 8.5e-44 149.7 24.0 5.2e-43 147.2 16.6 2.0 1 1 0 1 1 1 1 Rab effector MyRIP/melanophilin C-terminus NPV_P10 PF05531.7 KFM11493.1 - 0.053 13.7 3.9 8.2 6.7 0.3 3.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein zf-UDP PF14569.1 KFM11493.1 - 0.071 12.8 3.1 0.22 11.3 2.2 1.8 1 0 0 1 1 1 0 Zinc-binding RING-finger IncA PF04156.9 KFM11493.1 - 0.17 11.4 24.9 0.061 12.9 4.7 3.2 3 0 0 3 3 3 0 IncA protein MscS_porin PF12795.2 KFM11493.1 - 0.4 9.9 17.6 0.032 13.5 0.7 2.8 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain FlaC_arch PF05377.6 KFM11493.1 - 3.3 7.6 9.8 0.63 9.9 0.1 3.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Uds1 PF15456.1 KFM11493.1 - 3.8 7.5 25.0 0.43 10.5 0.4 4.7 4 1 0 4 4 4 0 Up-regulated During Septation AATF-Che1 PF13339.1 KFM11493.1 - 4.6 7.3 18.6 3.2 7.9 1.1 3.5 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor APG6 PF04111.7 KFM11493.1 - 4.7 6.1 32.3 0.77 8.7 1.3 3.2 3 0 0 3 3 3 0 Autophagy protein Apg6 MerR-DNA-bind PF09278.6 KFM11493.1 - 7.6 7.0 7.2 18 5.8 0.3 3.7 3 0 0 3 3 3 0 MerR, DNA binding Reo_sigmaC PF04582.7 KFM11493.1 - 8.2 5.5 8.5 0.23 10.5 0.8 2.0 3 0 0 3 3 3 0 Reovirus sigma C capsid protein Ras PF00071.17 KFM11494.1 - 2.8e-53 179.6 0.1 3.3e-53 179.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM11494.1 - 9.2e-18 64.8 0.0 1.8e-17 63.9 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFM11494.1 - 2.4e-15 56.2 0.0 3.1e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFM11494.1 - 0.00012 22.0 0.0 0.00017 21.4 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFM11494.1 - 0.0016 17.6 0.0 0.0018 17.4 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFM11494.1 - 0.0018 17.7 0.0 0.004 16.6 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain CPT PF07931.7 KFM11494.1 - 0.033 13.8 0.0 0.053 13.1 0.0 1.4 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DUF2051 PF09738.4 KFM11495.1 - 3e-94 315.6 68.3 4.3e-54 183.8 15.2 5.2 3 1 1 4 4 4 3 Double stranded RNA binding protein (DUF2051) Seryl_tRNA_N PF02403.17 KFM11495.1 - 0.01 15.8 6.1 0.01 15.8 4.3 6.2 4 2 2 6 6 6 0 Seryl-tRNA synthetase N-terminal domain Tweety PF04906.8 KFM11495.1 - 0.26 9.6 17.9 0.29 9.4 2.3 3.9 2 2 1 4 4 4 0 Tweety Fib_alpha PF08702.5 KFM11495.1 - 0.41 10.7 40.8 0.1 12.7 7.5 4.6 3 2 2 5 5 5 0 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.7 KFM11495.1 - 0.7 9.6 64.3 0.37 10.5 8.0 5.0 2 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein APG6 PF04111.7 KFM11495.1 - 1.6 7.6 64.5 0.79 8.7 7.7 4.7 2 1 3 5 5 5 0 Autophagy protein Apg6 IncA PF04156.9 KFM11495.1 - 3.5 7.1 68.3 1.7 8.1 9.2 5.1 2 1 2 4 4 4 0 IncA protein DUF3584 PF12128.3 KFM11495.1 - 4.4 4.4 52.0 0.1 9.9 13.6 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3584) UQ_con PF00179.21 KFM11497.1 - 3.3e-29 101.1 0.0 3.8e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFM11497.1 - 0.00069 19.3 0.0 0.00099 18.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B Methyltransf_11 PF08241.7 KFM11498.1 - 8.5e-25 87.0 0.0 3.3e-24 85.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFM11498.1 - 2e-16 59.9 0.0 2.8e-16 59.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFM11498.1 - 2.3e-13 49.8 0.0 3.6e-13 49.1 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 KFM11498.1 - 2.7e-13 49.9 0.0 3.6e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFM11498.1 - 3.2e-13 49.9 0.0 6.7e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFM11498.1 - 4.8e-12 46.2 0.0 8.3e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFM11498.1 - 3.7e-10 40.3 0.0 8e-10 39.2 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KFM11498.1 - 2.4e-08 33.8 0.0 7.3e-08 32.3 0.0 1.7 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_26 PF13659.1 KFM11498.1 - 2.2e-07 30.9 0.0 5.5e-07 29.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 KFM11498.1 - 6.4e-05 21.4 0.0 8.2e-05 21.1 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase TPMT PF05724.6 KFM11498.1 - 6.5e-05 22.4 0.0 0.0001 21.8 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) CMAS PF02353.15 KFM11498.1 - 0.00013 21.1 0.0 0.0002 20.5 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 KFM11498.1 - 0.00054 19.3 0.0 0.0017 17.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 KFM11498.1 - 0.00056 19.1 0.0 0.00084 18.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.7 KFM11498.1 - 0.00065 19.3 0.0 0.0024 17.4 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF938) tRNA_U5-meth_tr PF05958.6 KFM11498.1 - 0.0023 16.6 0.0 0.0029 16.3 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase DREV PF05219.7 KFM11498.1 - 0.0034 16.2 0.0 0.0048 15.8 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_32 PF13679.1 KFM11498.1 - 0.0035 17.0 0.0 0.0082 15.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 KFM11498.1 - 0.0063 16.0 0.0 1.1 8.6 0.0 2.6 2 1 0 2 2 2 1 DNA methylase Methyltransf_4 PF02390.12 KFM11498.1 - 0.014 14.4 0.0 0.12 11.4 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase RrnaAD PF00398.15 KFM11498.1 - 0.03 13.3 0.0 0.048 12.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TehB PF03848.9 KFM11498.1 - 0.06 12.5 0.0 0.14 11.3 0.0 1.6 1 1 0 1 1 1 0 Tellurite resistance protein TehB LacAB_rpiB PF02502.13 KFM11498.1 - 0.078 12.6 0.0 0.16 11.6 0.0 1.6 1 1 0 1 1 1 0 Ribose/Galactose Isomerase Methyltransf_15 PF09445.5 KFM11498.1 - 0.081 12.4 0.0 0.16 11.5 0.0 1.5 2 0 0 2 2 1 0 RNA cap guanine-N2 methyltransferase Pox_MCEL PF03291.11 KFM11498.1 - 0.09 11.6 0.0 0.32 9.8 0.0 1.7 2 0 0 2 2 2 0 mRNA capping enzyme COG5 PF10392.4 KFM11499.1 - 0.031 14.2 0.3 0.044 13.7 0.2 1.2 1 0 0 1 1 1 0 Golgi transport complex subunit 5 fn3 PF00041.16 KFM11500.1 - 4.8e-265 856.6 80.6 1.3e-20 73.3 0.6 17.4 17 0 0 17 17 17 17 Fibronectin type III domain fn1 PF00039.13 KFM11500.1 - 1.1e-151 492.2 166.1 9.5e-15 54.1 6.3 12.7 12 0 0 12 12 12 12 Fibronectin type I domain fn2 PF00040.14 KFM11500.1 - 6.3e-35 118.9 20.1 1.3e-17 63.4 4.8 3.3 2 0 0 2 2 2 2 Fibronectin type II domain Interfer-bind PF09294.5 KFM11500.1 - 3.8e-18 65.4 0.0 1 9.4 0.0 12.7 14 0 0 14 14 14 2 Interferon-alpha/beta receptor, fibronectin type III DUF2369 PF10179.4 KFM11500.1 - 2e-09 36.9 20.8 0.033 13.3 0.1 11.6 12 2 2 14 14 14 3 Uncharacterised conserved protein (DUF2369) DUF1410 PF07198.6 KFM11500.1 - 0.0018 18.5 5.8 28 5.1 0.0 7.6 8 0 0 8 8 8 0 Protein of unknown function (DUF1410) DUF2012 PF09430.5 KFM11500.1 - 0.035 13.9 0.4 13 5.5 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2012) fn3_3 PF14686.1 KFM11500.1 - 0.12 12.5 3.5 13 5.9 0.1 4.5 6 0 0 6 6 6 0 Polysaccharide lyase family 4, domain II Glyco_hydro_66 PF13199.1 KFM11500.1 - 0.22 9.8 6.5 8.3 4.6 0.0 5.1 6 0 0 6 6 6 0 Glycosyl hydrolase family 66 AICARFT_IMPCHas PF01808.13 KFM11502.1 - 1.3e-119 398.9 0.4 1.7e-119 398.5 0.3 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 KFM11502.1 - 1e-24 86.2 0.0 2.1e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain DFP PF04127.10 KFM11502.1 - 0.053 13.1 0.4 0.1 12.1 0.3 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein ABC_tran PF00005.22 KFM11503.1 - 1.3e-53 180.9 2.6 3.7e-29 101.7 0.0 3.4 3 1 0 3 3 3 2 ABC transporter ABC2_membrane_3 PF12698.2 KFM11503.1 - 8.3e-45 153.3 50.0 2.2e-25 89.4 11.3 3.5 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.1 KFM11503.1 - 2.5e-25 90.0 4.1 2.5e-10 40.8 0.2 4.4 2 2 0 3 3 3 3 AAA domain SMC_N PF02463.14 KFM11503.1 - 0.00053 19.2 0.7 21 4.2 0.1 4.3 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.12 KFM11503.1 - 0.003 16.9 0.9 0.44 9.9 0.0 3.1 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_29 PF13555.1 KFM11503.1 - 0.0085 15.6 5.5 0.12 11.8 0.3 2.9 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_23 PF13476.1 KFM11503.1 - 0.013 15.8 0.1 0.013 15.8 0.1 4.3 4 1 0 4 4 3 0 AAA domain DUF258 PF03193.11 KFM11503.1 - 0.014 14.6 0.9 1.6 7.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DUF4162 PF13732.1 KFM11503.1 - 0.052 14.0 0.0 0.27 11.7 0.0 2.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4162) SbcCD_C PF13558.1 KFM11503.1 - 0.069 13.0 0.0 16 5.5 0.0 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit SRP54 PF00448.17 KFM11503.1 - 0.2 11.0 3.7 1.4 8.3 0.1 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Ank_4 PF13637.1 KFM11504.1 - 5.2e-28 96.8 2.7 6.3e-13 48.8 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 KFM11504.1 - 1.3e-27 94.1 4.1 2.2e-08 33.4 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 KFM11504.1 - 3.4e-25 88.1 1.2 6e-18 64.9 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFM11504.1 - 9.7e-23 79.6 2.4 1.8e-09 37.5 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM11504.1 - 3.4e-20 70.1 0.9 3.8e-06 26.6 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat zf-RING_6 PF14835.1 KFM11504.1 - 4.1e-15 55.2 0.7 4.1e-15 55.2 0.5 2.1 2 0 0 2 2 2 1 zf-RING of BARD1-type protein BRCT PF00533.21 KFM11504.1 - 5.8e-12 45.5 0.0 1.2e-05 25.3 0.0 2.6 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KFM11504.1 - 0.0045 16.8 0.0 0.19 11.6 0.0 2.6 2 0 0 2 2 2 1 twin BRCT domain VWC PF00093.13 KFM11505.1 - 2.9e-09 36.8 53.2 7.3e-06 25.9 11.9 3.2 3 0 0 3 3 3 3 von Willebrand factor type C domain Pacifastin_I PF05375.8 KFM11505.1 - 0.00067 19.1 4.0 0.00067 19.1 2.8 4.0 3 0 0 3 3 3 2 Pacifastin inhibitor (LCMII) WD40 PF00400.27 KFM11507.1 - 7.4e-33 111.2 23.0 2.4e-10 39.8 2.4 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat eIF2A PF08662.6 KFM11507.1 - 0.001 18.8 1.5 0.0037 17.0 0.5 2.0 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KFM11507.1 - 0.039 12.0 4.0 0.26 9.3 1.2 2.8 1 1 1 2 2 2 0 Nucleoporin Nup120/160 zf-H2C2_2 PF13465.1 KFM11509.1 - 1.3e-22 78.8 34.3 1.4e-08 34.6 1.9 6.4 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2 PF00096.21 KFM11509.1 - 4e-15 55.1 48.0 9.4e-05 22.5 0.9 6.7 7 0 0 7 7 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM11509.1 - 7.1e-11 41.6 40.7 0.00097 19.3 0.6 6.5 6 0 0 6 6 6 4 C2H2-type zinc finger GAGA PF09237.6 KFM11509.1 - 0.018 14.6 5.6 0.086 12.4 0.0 3.2 2 1 1 3 3 3 0 GAGA factor zf-MYND PF01753.13 KFM11509.1 - 0.018 14.9 9.3 0.12 12.2 0.0 3.7 3 1 0 3 3 3 0 MYND finger zf-C2H2_jaz PF12171.3 KFM11509.1 - 0.02 15.0 30.8 0.49 10.5 0.4 6.9 7 1 1 8 8 8 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 KFM11509.1 - 0.036 14.2 1.0 0.036 14.2 0.7 6.2 6 0 0 6 6 6 0 C2H2-type zinc-finger domain zf-met PF12874.2 KFM11509.1 - 0.088 13.0 0.2 0.088 13.0 0.1 6.5 6 1 1 7 7 7 0 Zinc-finger of C2H2 type zf-TRAF PF02176.13 KFM11509.1 - 0.34 11.3 16.4 0.12 12.8 2.3 3.7 2 1 1 3 3 3 0 TRAF-type zinc finger zf-C2H2_6 PF13912.1 KFM11509.1 - 1 9.3 37.7 0.33 10.9 2.6 7.2 7 1 0 7 7 7 0 C2H2-type zinc finger zf-CHCC PF10276.4 KFM11509.1 - 4 7.3 11.9 0.25 11.2 0.2 3.5 4 0 0 4 4 4 0 Zinc-finger domain GATA PF00320.22 KFM11509.1 - 4.6 6.6 14.2 7.1 6.0 0.1 4.2 4 0 0 4 4 4 0 GATA zinc finger DUF2321 PF10083.4 KFM11509.1 - 6 6.3 11.1 0.5 9.8 2.7 2.6 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-C2H2_2 PF12756.2 KFM11509.1 - 6 7.0 27.7 9.2 6.4 2.5 5.4 3 2 2 5 5 5 0 C2H2 type zinc-finger (2 copies) BCDHK_Adom3 PF10436.4 KFM11510.1 - 3.3e-26 91.7 0.0 4.4e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KFM11510.1 - 3.9e-17 61.9 0.0 9.3e-17 60.7 0.0 1.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-H2C2_2 PF13465.1 KFM11511.1 - 1.7e-48 160.6 42.3 9.1e-08 32.0 0.1 8.8 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.21 KFM11511.1 - 1.3e-39 132.1 39.1 6.7e-06 26.1 0.3 8.2 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM11511.1 - 8.3e-23 78.9 39.0 0.0024 18.1 0.3 8.2 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM11511.1 - 1.1e-17 63.2 31.8 0.0019 18.0 0.4 7.5 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM11511.1 - 2.9e-16 59.0 9.8 0.0069 16.4 0.0 7.2 7 0 0 7 7 7 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM11511.1 - 2.4e-08 33.9 21.6 0.0038 17.3 0.1 6.8 7 0 0 7 7 7 2 Zinc-finger of C2H2 type zf-LYAR PF08790.6 KFM11511.1 - 0.0009 18.8 17.6 0.11 12.2 0.2 5.8 7 0 0 7 7 7 2 LYAR-type C2HC zinc finger XPA_N PF01286.13 KFM11511.1 - 0.0028 17.2 16.4 10 5.9 0.1 6.6 7 0 0 7 7 7 0 XPA protein N-terminal Zn-ribbon_8 PF09723.5 KFM11511.1 - 0.0051 16.7 25.2 0.083 12.8 1.2 6.7 5 2 1 6 6 6 1 Zinc ribbon domain C1_4 PF07975.7 KFM11511.1 - 0.013 15.4 14.0 7 6.7 0.0 5.5 2 1 5 7 7 7 0 TFIIH C1-like domain DUF164 PF02591.10 KFM11511.1 - 0.071 12.9 0.8 0.071 12.9 0.5 4.5 4 2 0 4 4 4 0 Putative zinc ribbon domain zf-C2HC_2 PF13913.1 KFM11511.1 - 0.29 10.8 0.2 0.29 10.8 0.1 5.3 5 1 0 5 5 5 0 zinc-finger of a C2HC-type FYDLN_acid PF09538.5 KFM11511.1 - 0.45 11.1 10.1 30 5.2 0.6 5.4 2 1 2 4 4 4 0 Protein of unknown function (FYDLN_acid) DZR PF12773.2 KFM11511.1 - 0.55 10.0 28.0 4.2e+02 0.8 0.5 5.1 1 1 1 2 2 1 0 Double zinc ribbon zf-AN1 PF01428.11 KFM11511.1 - 3.3 7.6 25.4 14 5.6 0.2 6.9 7 0 0 7 7 7 0 AN1-like Zinc finger zf-RING_3 PF14369.1 KFM11511.1 - 3.6 7.6 22.1 6 6.9 0.1 6.0 6 0 0 6 6 6 0 zinc-finger zf-H2C2_2 PF13465.1 KFM11512.1 - 7.4e-56 183.8 40.6 9.8e-09 35.0 0.3 8.5 9 0 0 9 9 8 7 Zinc-finger double domain zf-C2H2 PF00096.21 KFM11512.1 - 5.6e-47 155.3 46.7 2.1e-06 27.7 0.1 8.7 8 1 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM11512.1 - 9.9e-30 100.6 40.4 4.8e-05 23.3 0.8 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM11512.1 - 8.5e-27 92.1 41.8 0.00043 20.0 0.3 8.3 8 0 0 8 8 8 8 C2H2-type zinc finger XPA_N PF01286.13 KFM11512.1 - 7.1e-09 35.1 22.6 1.3 8.7 0.1 8.0 8 0 0 8 8 8 3 XPA protein N-terminal zf-C2H2_jaz PF12171.3 KFM11512.1 - 3.3e-08 33.4 25.8 0.21 11.7 0.0 8.0 8 1 0 8 8 8 3 Zinc-finger double-stranded RNA-binding RRN7 PF11781.3 KFM11512.1 - 5.5e-07 28.9 29.5 0.15 11.6 0.1 7.5 8 0 0 8 8 8 4 RNA polymerase I-specific transcription initiation factor Rrn7 Zn-ribbon_8 PF09723.5 KFM11512.1 - 5.9e-06 26.1 33.8 1.9 8.5 0.1 7.7 5 3 1 6 6 6 2 Zinc ribbon domain zf-LYAR PF08790.6 KFM11512.1 - 6.3e-05 22.5 13.8 9.7 5.9 0.0 7.5 8 0 0 8 8 8 0 LYAR-type C2HC zinc finger C1_4 PF07975.7 KFM11512.1 - 0.00069 19.5 20.6 0.2 11.6 0.9 6.0 1 1 6 7 7 7 2 TFIIH C1-like domain LIM PF00412.17 KFM11512.1 - 0.00071 19.6 20.7 0.082 12.9 0.4 5.6 2 1 3 6 6 6 3 LIM domain Zn_ribbon_recom PF13408.1 KFM11512.1 - 0.0037 17.4 34.8 2.7 8.3 1.1 6.8 2 1 3 6 6 6 2 Recombinase zinc beta ribbon domain DrsE PF02635.10 KFM11512.1 - 0.0057 16.7 1.3 18 5.3 0.0 4.2 1 1 3 5 5 5 0 DsrE/DsrF-like family DNA_RNApol_7kD PF03604.8 KFM11512.1 - 0.011 15.1 37.1 2.9 7.4 0.1 8.0 8 0 0 8 8 8 0 DNA directed RNA polymerase, 7 kDa subunit YhfH PF14149.1 KFM11512.1 - 0.038 13.7 23.1 17 5.3 0.0 7.3 7 0 0 7 7 7 0 YhfH-like protein zf-UBP PF02148.14 KFM11512.1 - 0.25 11.4 32.0 58 3.8 0.5 5.6 1 1 3 4 4 4 0 Zn-finger in ubiquitin-hydrolases and other protein zf-trcl PF13451.1 KFM11512.1 - 0.4 10.3 30.8 4.3 7.0 0.0 7.5 7 1 0 7 7 7 0 Probable zinc-binding domain DUF2321 PF10083.4 KFM11512.1 - 0.63 9.5 22.0 4 6.9 0.2 5.9 1 1 5 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2321) Yippee-Mis18 PF03226.9 KFM11512.1 - 0.81 9.7 18.5 25 5.0 0.5 5.4 2 2 1 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly CpXC PF14353.1 KFM11512.1 - 3.5 7.5 17.3 52 3.8 0.0 6.5 7 1 0 8 8 8 0 CpXC protein FYDLN_acid PF09538.5 KFM11512.1 - 3.6 8.2 15.2 26 5.4 0.1 5.9 1 1 3 4 4 4 0 Protein of unknown function (FYDLN_acid) Mut7-C PF01927.11 KFM11512.1 - 5.9 6.8 20.2 0.83 9.6 0.9 4.6 1 1 2 3 3 2 0 Mut7-C RNAse domain zf-AN1 PF01428.11 KFM11512.1 - 6.8 6.6 32.3 25 4.8 0.1 7.8 7 1 1 8 8 8 0 AN1-like Zinc finger zf-TRAF PF02176.13 KFM11512.1 - 7.5 7.0 20.1 0.58 10.5 0.8 4.2 1 1 4 5 5 5 0 TRAF-type zinc finger Pkinase PF00069.20 KFM11513.1 - 5.1e-58 196.2 0.0 6.2e-58 195.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM11513.1 - 1.2e-27 96.6 0.0 1.5e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM11513.1 - 0.0016 17.5 0.0 0.0022 16.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFM11513.1 - 0.0043 16.1 0.0 0.0067 15.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KFM11514.1 - 7.4e-69 231.7 0.0 1e-68 231.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM11514.1 - 1.9e-37 128.7 0.0 3e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM11514.1 - 5.5e-05 22.2 0.0 9.9e-05 21.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KFM11514.1 - 0.00073 18.9 0.1 0.0013 18.1 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KFM11514.1 - 0.0029 16.6 0.0 0.0055 15.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFM11514.1 - 0.065 12.9 0.2 0.24 11.1 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family TPR_11 PF13414.1 KFM11515.1 - 6.4e-14 51.3 0.3 1.5e-10 40.5 0.1 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KFM11515.1 - 2.1e-09 36.5 0.0 0.00053 19.7 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFM11515.1 - 1.1e-08 35.4 0.2 0.0053 17.4 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFM11515.1 - 2.6e-06 27.5 1.5 0.1 13.2 0.0 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFM11515.1 - 4.1e-05 23.4 0.0 0.018 15.2 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFM11515.1 - 0.00013 22.2 0.3 0.024 14.9 0.0 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFM11515.1 - 0.00014 21.6 1.2 0.19 11.5 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFM11515.1 - 0.00017 21.0 0.0 0.73 9.5 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat ChAPs PF09295.5 KFM11515.1 - 0.0024 16.6 0.4 0.0032 16.3 0.3 1.2 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_12 PF13424.1 KFM11515.1 - 0.013 15.4 0.2 1.9 8.4 0.1 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat Vasohibin PF14822.1 KFM11515.1 - 0.034 13.2 0.1 0.052 12.6 0.1 1.3 1 0 0 1 1 1 0 Vasohibin Maf_N PF08383.6 KFM11515.1 - 0.088 12.3 0.4 0.33 10.5 0.0 2.1 2 0 0 2 2 2 0 Maf N-terminal region DUF4107 PF13389.1 KFM11515.1 - 0.1 12.2 1.1 0.29 10.8 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4107) DUF4110 PF13422.1 KFM11515.1 - 4.4 7.2 8.6 2.7 7.8 1.7 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4110) 7tm_1 PF00001.16 KFM11516.1 - 2.3e-44 151.4 12.1 2.8e-44 151.1 8.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 KFM11516.1 - 4.3e-07 29.3 15.1 5.9e-07 28.8 10.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx NdhL PF10716.4 KFM11516.1 - 0.0056 16.4 1.2 0.015 15.0 0.0 2.3 2 0 0 2 2 2 1 NADH dehydrogenase transmembrane subunit EIIC-GAT PF03611.9 KFM11516.1 - 0.63 8.7 9.4 0.16 10.7 1.5 2.2 1 1 1 2 2 2 0 PTS system sugar-specific permease component Nbl1_Borealin_N PF10444.4 KFM11517.1 - 0.046 13.0 1.0 0.11 11.8 0.1 2.1 1 1 1 2 2 2 0 Nbl1 / Borealin N terminal P22_AR_N PF10547.4 KFM11517.1 - 0.057 13.2 0.5 0.066 13.0 0.4 1.1 1 0 0 1 1 1 0 P22_AR N-terminal domain hSH3 PF14603.1 KFM11519.1 - 4.1e-31 106.8 9.8 3.4e-24 84.6 0.0 4.3 4 1 0 4 4 4 2 Helically-extended SH3 domain SH3_2 PF07653.12 KFM11519.1 - 2.4e-07 30.1 0.6 7.6e-07 28.5 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 KFM11519.1 - 0.0014 17.9 0.3 0.84 9.0 0.0 2.5 2 0 0 2 2 2 2 SH3 domain DUF4651 PF15513.1 KFM11519.1 - 0.0032 16.8 0.1 1.9 8.0 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4651) DUF4391 PF14335.1 KFM11519.1 - 0.11 11.9 0.1 0.11 11.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4391) RICTOR_N PF14664.1 KFM11520.1 - 2.4e-118 394.9 1.0 4.1e-118 394.1 0.7 1.4 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 KFM11520.1 - 1.3e-64 217.2 10.3 1.7e-64 216.9 2.1 3.4 3 1 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_phospho PF14665.1 KFM11520.1 - 9.2e-50 167.4 2.5 1.4e-49 166.8 0.5 2.4 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, phosphorylation-site RasGEF_N_2 PF14663.1 KFM11520.1 - 5.9e-41 139.0 0.2 5.9e-41 139.0 0.1 2.5 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 KFM11520.1 - 5.2e-33 112.8 5.5 1.1e-31 108.5 0.3 4.2 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_2 PF13646.1 KFM11520.1 - 0.00048 20.3 2.7 0.44 10.8 0.0 4.4 4 0 0 4 4 4 1 HEAT repeats 7TM_GPCR_Srbc PF10316.4 KFM11520.1 - 0.11 11.7 2.8 4.3 6.5 0.0 2.7 2 1 0 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srbc HEAT_EZ PF13513.1 KFM11520.1 - 0.19 12.2 2.0 14 6.3 0.0 4.2 3 0 0 3 3 3 0 HEAT-like repeat fn3 PF00041.16 KFM11521.1 - 2.5e-15 56.3 7.3 4.1e-05 23.6 0.2 5.2 5 0 0 5 5 5 3 Fibronectin type III domain PKD PF00801.15 KFM11521.1 - 0.032 13.9 0.2 2.3 8.0 0.0 3.7 3 0 0 3 3 3 0 PKD domain IL6Ra-bind PF09240.5 KFM11521.1 - 2.5 8.2 10.8 42 4.3 5.7 3.3 2 1 0 2 2 2 0 Interleukin-6 receptor alpha chain, binding fn3 PF00041.16 KFM11522.1 - 2.3e-19 69.3 3.4 3.9e-05 23.6 0.0 6.4 5 2 1 6 6 6 3 Fibronectin type III domain IL6Ra-bind PF09240.5 KFM11522.1 - 1.8e-09 37.6 1.5 0.0017 18.4 0.0 3.5 3 0 0 3 3 3 2 Interleukin-6 receptor alpha chain, binding EpoR_lig-bind PF09067.5 KFM11522.1 - 1e-05 25.4 0.3 0.0077 16.1 0.0 2.7 2 0 0 2 2 2 2 Erythropoietin receptor, ligand binding Lep_receptor_Ig PF06328.6 KFM11522.1 - 0.11 12.4 1.4 0.21 11.4 0.1 2.2 2 1 0 2 2 2 0 Ig-like C2-type domain CD34_antigen PF06365.7 KFM11522.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Laminin_G_2 PF02210.19 KFM11523.1 - 4.8e-85 282.0 0.2 3.7e-29 101.3 0.0 3.4 3 0 0 3 3 3 3 Laminin G domain Laminin_G_1 PF00054.18 KFM11523.1 - 4.5e-82 272.5 0.0 7.4e-26 90.7 0.0 3.2 3 0 0 3 3 3 3 Laminin G domain fn3 PF00041.16 KFM11523.1 - 4.1e-23 81.3 0.0 5e-12 45.7 0.0 2.8 2 0 0 2 2 2 2 Fibronectin type III domain Laminin_G_3 PF13385.1 KFM11523.1 - 8.6e-13 48.8 0.4 0.0027 17.9 0.0 3.4 3 0 0 3 3 3 3 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.22 KFM11523.1 - 1.2e-08 34.7 35.0 6.5e-07 29.1 4.9 3.6 3 0 0 3 3 3 2 EGF-like domain Stirrup PF09061.1 KFM11523.1 - 1.3e-05 24.9 0.1 0.039 13.8 0.0 3.4 3 0 0 3 3 3 1 Stirrup hEGF PF12661.2 KFM11523.1 - 0.43 10.7 24.5 0.12 12.4 0.8 4.3 4 0 0 4 4 4 0 Human growth factor-like EGF TGF_beta PF00019.15 KFM11524.1 - 4.5e-18 65.4 1.1 6.6e-18 64.9 0.8 1.2 1 0 0 1 1 1 1 Transforming growth factor beta like domain Hamartin PF04388.7 KFM11524.1 - 0.023 13.4 0.0 0.023 13.4 0.0 1.1 1 0 0 1 1 1 0 Hamartin protein LEAP-2 PF07359.6 KFM11524.1 - 0.057 13.0 0.7 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Nucleoporin_C PF03177.9 KFM11525.1 - 3.6e-107 359.2 11.1 4.7e-107 358.9 7.7 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 KFM11525.1 - 3.6e-94 315.9 0.0 5.2e-94 315.3 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Cryptochrome_C PF12546.3 KFM11527.1 - 0.0091 16.6 2.1 0.014 16.1 1.5 1.4 1 1 0 1 1 1 1 Blue/Ultraviolet sensing protein C terminal Dynactin_p62 PF05502.8 KFM11527.1 - 0.037 12.8 1.5 0.041 12.6 1.0 1.0 1 0 0 1 1 1 0 Dynactin p62 family DUF2481 PF10654.4 KFM11527.1 - 0.11 12.1 0.2 0.13 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2481) YlbD_coat PF14071.1 KFM11527.1 - 0.47 10.5 4.5 0.59 10.1 3.1 1.2 1 0 0 1 1 1 0 Putative coat protein Joubert PF15392.1 KFM11530.1 - 2.3e-18 66.4 0.3 2.4e-18 66.4 0.2 1.1 1 0 0 1 1 1 1 Joubert syndrome-associated Nipped-B_C PF12830.2 KFM11531.1 - 1.7e-62 210.4 1.1 1.7e-62 210.4 0.7 2.7 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus HEAT_2 PF13646.1 KFM11531.1 - 1e-05 25.6 0.0 0.024 14.9 0.0 3.4 3 0 0 3 3 3 2 HEAT repeats Cohesin_HEAT PF12765.2 KFM11532.1 - 1.9e-17 62.7 0.1 3.2e-17 62.0 0.1 1.4 1 0 0 1 1 1 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 KFM11532.1 - 7e-06 25.7 0.4 0.0024 17.7 0.0 2.3 2 0 0 2 2 2 2 HEAT repeat HEAT_EZ PF13513.1 KFM11532.1 - 0.00041 20.7 0.1 0.0011 19.3 0.0 1.8 1 1 0 1 1 1 1 HEAT-like repeat HEAT_2 PF13646.1 KFM11532.1 - 0.0016 18.6 0.1 0.002 18.3 0.0 1.2 1 0 0 1 1 1 1 HEAT repeats Cnd3 PF12719.2 KFM11532.1 - 0.0075 15.2 0.1 0.19 10.7 0.0 2.0 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain MMS19_N PF14500.1 KFM11532.1 - 0.054 12.7 0.1 2.8 7.1 0.0 2.0 1 1 1 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II CcmH PF03918.9 KFM11532.1 - 0.12 11.3 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Cytochrome C biogenesis protein Nipped-B_C PF12830.2 KFM11533.1 - 0.038 13.6 0.3 0.048 13.3 0.2 1.2 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus Pex26 PF07163.7 KFM11533.1 - 0.092 11.6 0.0 0.093 11.6 0.0 1.1 1 0 0 1 1 1 0 Pex26 protein SDF PF00375.13 KFM11535.1 - 2.6e-137 457.7 32.5 3e-137 457.5 22.6 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family MT PF12777.2 KFM11535.1 - 0.0082 14.9 0.0 0.014 14.1 0.0 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Ran_BP1 PF00638.13 KFM11536.1 - 5.4e-12 45.8 0.0 9.4e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain NAD_kinase PF01513.16 KFM11537.1 - 1.6e-09 36.9 0.0 2.9e-08 32.8 0.0 2.5 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 KFM11537.1 - 0.01 15.2 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain F-box-like PF12937.2 KFM11538.1 - 2.7e-16 59.0 3.2 8.7e-16 57.3 2.2 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFM11538.1 - 6.7e-09 35.1 2.2 6.7e-09 35.1 1.6 3.0 3 0 0 3 3 3 1 F-box domain LRR_6 PF13516.1 KFM11538.1 - 6.4e-06 25.7 12.5 3.3 8.0 0.0 7.1 7 0 0 7 7 7 2 Leucine Rich repeat LRR_1 PF00560.28 KFM11538.1 - 0.00029 20.4 13.3 12 6.4 0.1 7.5 6 2 0 6 6 6 2 Leucine Rich Repeat LRR_4 PF12799.2 KFM11538.1 - 0.0074 15.8 6.1 13 5.4 0.1 4.7 3 1 1 4 4 4 1 Leucine Rich repeats (2 copies) F-box-like_2 PF13013.1 KFM11538.1 - 0.032 13.9 0.7 0.078 12.7 0.5 1.9 1 1 0 1 1 1 0 F-box-like domain LMBR1 PF04791.11 KFM11539.1 - 4.1e-103 345.4 20.2 4.1e-103 345.4 14.0 1.5 2 0 0 2 2 2 1 LMBR1-like membrane protein EF-hand_1 PF00036.27 KFM11540.1 - 5.8e-25 84.6 11.1 2.7e-09 35.6 0.4 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 KFM11540.1 - 1.5e-23 80.5 7.5 3.1e-07 29.7 0.0 4.5 4 1 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 KFM11540.1 - 1.5e-19 69.9 9.3 1.1e-09 38.3 2.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KFM11540.1 - 7e-15 53.6 19.0 1.2e-05 24.4 2.6 5.1 5 1 1 6 6 6 4 EF hand EF-hand_8 PF13833.1 KFM11540.1 - 2.3e-14 52.7 12.1 4.1e-08 32.7 0.9 3.7 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.2 KFM11540.1 - 0.00013 21.6 2.3 0.071 12.8 0.1 3.0 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KFM11540.1 - 0.12 12.2 1.4 2 8.3 0.0 3.0 2 1 1 3 3 3 0 EF-hand domain EF-hand_10 PF14788.1 KFM11540.1 - 0.2 11.3 2.4 1.6 8.4 0.6 2.9 3 1 1 4 4 4 0 EF hand fn3 PF00041.16 KFM11541.1 - 0.039 14.0 0.2 1.7 8.8 0.1 2.6 2 0 0 2 2 2 0 Fibronectin type III domain EpoR_lig-bind PF09067.5 KFM11542.1 - 1e-51 173.2 0.5 7.1e-26 90.2 0.0 2.6 2 0 0 2 2 2 2 Erythropoietin receptor, ligand binding IL6Ra-bind PF09240.5 KFM11542.1 - 1.8e-21 76.1 1.1 4.5e-10 39.5 0.0 2.7 2 0 0 2 2 2 2 Interleukin-6 receptor alpha chain, binding fn3 PF00041.16 KFM11542.1 - 3.5e-17 62.2 14.6 4.6e-07 29.8 0.4 5.2 5 0 0 5 5 5 3 Fibronectin type III domain Tissue_fac PF01108.12 KFM11542.1 - 8.5e-05 22.2 7.6 0.21 11.3 0.0 4.1 4 0 0 4 4 4 2 Tissue factor DUF3047 PF11249.3 KFM11542.1 - 0.022 14.1 0.1 0.05 12.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3047) Lipase3_N PF03893.11 KFM11542.1 - 0.079 12.7 0.5 2.8 7.8 0.0 2.6 2 0 0 2 2 2 0 Lipase 3 N-terminal region zf-C2H2_jaz PF12171.3 KFM11543.1 - 2.9e-11 43.1 7.1 2.9e-10 39.9 0.8 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding DnaJ PF00226.26 KFM11543.1 - 7e-09 35.2 1.9 2e-08 33.8 0.3 2.7 2 0 0 2 2 2 1 DnaJ domain zf-met PF12874.2 KFM11543.1 - 3.2e-07 30.3 8.6 6.5e-07 29.3 0.8 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KFM11543.1 - 1.4e-05 25.1 7.8 0.022 14.8 0.1 3.2 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 KFM11543.1 - 0.24 11.8 5.1 1.5 9.3 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KFM11543.1 - 2.2 8.7 8.8 8 7.0 1.3 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF2779 PF11074.3 KFM11543.1 - 6.9 6.7 10.9 15 5.6 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function(DUF2779) Brix PF04427.13 KFM11544.1 - 2.3e-44 151.3 0.9 2.3e-44 151.3 0.6 1.5 2 0 0 2 2 2 1 Brix domain AcylCoA_DH_N PF12418.3 KFM11544.1 - 0.096 12.3 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase N terminal Rad1 PF02144.11 KFM11545.1 - 1.2e-83 280.0 0.8 1.4e-83 279.8 0.6 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Ank_2 PF12796.2 KFM11546.1 - 7.1e-45 151.2 7.9 1.2e-17 64.0 0.5 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFM11546.1 - 4.3e-44 146.1 11.4 3.1e-08 33.0 0.1 6.6 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 KFM11546.1 - 2e-40 135.8 14.7 2.2e-12 46.7 0.1 6.7 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFM11546.1 - 1.4e-39 133.7 10.3 1.8e-11 44.2 0.0 5.6 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM11546.1 - 4.5e-32 106.8 6.5 6.2e-06 25.9 0.1 6.8 6 0 0 6 6 6 5 Ankyrin repeat FlxA PF14282.1 KFM11546.1 - 0.00034 20.5 21.7 0.00034 20.5 15.1 8.3 3 3 3 7 7 7 1 FlxA-like protein Surfac_D-trimer PF09006.6 KFM11546.1 - 3.1 7.6 8.3 9.8 6.0 3.9 3.2 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation C1q PF00386.16 KFM11547.1 - 1.9e-32 111.9 3.7 2.4e-32 111.6 2.6 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 KFM11547.1 - 4.9e-13 48.4 57.1 2.5e-10 39.7 22.6 2.0 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) CoA_transf_3 PF02515.12 KFM11548.1 - 5.1e-43 146.5 0.0 6.3e-43 146.2 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III MFS_2 PF13347.1 KFM11549.1 - 7.8e-18 64.0 15.5 5.9e-17 61.1 10.7 1.9 1 1 0 1 1 1 1 MFS/sugar transport protein 7tm_1 PF00001.16 KFM11550.1 - 1.4e-52 178.3 16.7 1.9e-52 177.9 11.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) UPF0182 PF03699.8 KFM11550.1 - 0.6 7.9 8.0 0.72 7.7 5.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) HEV_ORF1 PF02444.11 KFM11551.1 - 0.21 11.7 6.9 0.27 11.4 4.8 1.3 1 0 0 1 1 1 0 Hepatitis E virus ORF-2 (Putative capsid protein) tRNA-synt_2b PF00587.20 KFM11552.1 - 1.5e-46 158.1 1.2 2e-46 157.7 0.2 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KFM11552.1 - 3.7e-19 68.4 0.1 8.2e-19 67.3 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 KFM11552.1 - 2.1e-18 65.9 0.1 1.4e-17 63.2 0.0 2.2 2 0 0 2 2 2 1 TGS domain tRNA_SAD PF07973.9 KFM11552.1 - 1.8e-12 46.9 0.1 3.9e-12 45.8 0.1 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain ANF_receptor PF01094.23 KFM11553.1 - 1.4e-36 126.0 0.8 1.7e-36 125.7 0.6 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region DUF2555 PF10742.4 KFM11553.1 - 0.078 12.6 0.0 0.24 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2555) Peripla_BP_6 PF13458.1 KFM11553.1 - 0.13 11.5 0.0 0.26 10.6 0.0 1.5 1 1 0 1 1 1 0 Periplasmic binding protein RVT_1 PF00078.22 KFM11554.1 - 0.018 14.4 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) PC4 PF02229.11 KFM11555.1 - 1.3e-23 81.9 0.3 2.3e-23 81.1 0.2 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) QLQ PF08880.6 KFM11555.1 - 0.016 14.5 0.2 0.023 14.0 0.2 1.2 1 0 0 1 1 1 0 QLQ SR-25 PF10500.4 KFM11555.1 - 0.08 12.3 12.2 0.11 11.9 8.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RNA_pol_Rpc4 PF05132.9 KFM11555.1 - 0.19 11.7 2.8 0.21 11.5 1.9 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 RR_TM4-6 PF06459.7 KFM11555.1 - 1.8 8.3 5.3 2.2 8.1 3.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4557 PF15101.1 KFM11555.1 - 2.1 8.1 5.3 3 7.6 2.6 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4557) DZF PF07528.9 KFM11556.1 - 2.2e-65 220.4 0.0 3.7e-65 219.7 0.0 1.4 1 0 0 1 1 1 1 DZF domain zf-met PF12874.2 KFM11556.1 - 2.3e-21 75.2 15.6 1.8e-06 27.9 1.5 3.7 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFM11556.1 - 2.1e-13 49.9 20.4 8e-05 22.6 1.6 4.0 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFM11556.1 - 0.0073 16.3 17.1 1.2 9.3 0.3 4.1 3 1 1 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.7 KFM11556.1 - 0.12 11.9 18.3 0.34 10.5 1.8 3.6 3 0 0 3 3 3 0 U1 zinc finger Myotub-related PF06602.9 KFM11557.1 - 1.9e-62 211.0 5.8 4.6e-52 176.9 3.2 2.1 1 1 1 2 2 2 2 Myotubularin-like phosphatase domain 3-PAP PF12578.3 KFM11557.1 - 3.4e-30 104.7 0.0 6.1e-30 103.9 0.0 1.4 1 0 0 1 1 1 1 Myotubularin-associated protein MLANA PF14991.1 KFM11557.1 - 0.015 15.3 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Protein melan-A GPP34 PF05719.6 KFM11558.1 - 3.5e-59 200.3 2.5 4.2e-59 200.0 1.8 1.0 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Peptidase_M15_2 PF05951.8 KFM11558.1 - 0.027 13.8 0.1 0.048 13.0 0.1 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) PDZ PF00595.19 KFM11559.1 - 2.6e-51 171.7 5.4 6.6e-20 71.0 0.3 4.5 4 0 0 4 4 4 4 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM11559.1 - 1.5e-15 56.8 0.0 0.00076 19.3 0.0 4.9 5 0 0 5 5 5 4 PDZ domain Collagen PF01391.13 KFM11560.1 - 1.5e-14 53.2 48.4 6.2e-08 32.0 18.2 2.4 2 0 0 2 2 2 2 Collagen triple helix repeat (20 copies) FXa_inhibition PF14670.1 KFM11560.1 - 9.7e-10 38.4 30.6 1.4e-09 37.9 7.3 2.8 3 0 0 3 3 3 2 Coagulation Factor Xa inhibitory site EGF_CA PF07645.10 KFM11560.1 - 1.2e-09 38.0 9.7 1.2e-09 38.0 6.7 3.0 3 1 0 3 3 3 1 Calcium-binding EGF domain cEGF PF12662.2 KFM11560.1 - 8.3e-08 31.7 14.1 4.5e-06 26.2 2.8 3.3 4 0 0 4 4 4 2 Complement Clr-like EGF-like EGF PF00008.22 KFM11560.1 - 7.2e-05 22.6 20.3 0.0014 18.5 3.6 3.1 3 0 0 3 3 3 2 EGF-like domain EGF_3 PF12947.2 KFM11560.1 - 0.0011 18.8 19.9 0.032 14.1 1.4 2.8 2 0 0 2 2 2 2 EGF domain Tme5_EGF_like PF09064.5 KFM11560.1 - 0.18 11.4 16.3 0.44 10.2 2.2 2.7 2 0 0 2 2 2 0 Thrombomodulin like fifth domain, EGF-like hEGF PF12661.2 KFM11560.1 - 0.39 10.8 6.6 7.8 6.8 0.3 3.5 2 0 0 2 2 2 0 Human growth factor-like EGF Ribosomal_L17 PF01196.14 KFM11561.1 - 1.3e-12 48.0 0.0 2e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L17 DUF3322 PF11795.3 KFM11561.1 - 0.12 11.9 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) RhoGEF PF00621.15 KFM11562.1 - 3.4e-32 111.7 1.5 4.8e-32 111.2 1.0 1.2 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 KFM11562.1 - 3.3e-06 27.2 0.0 3.1e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 PH domain DDE_Tnp_IS240 PF13610.1 KFM11562.1 - 0.34 10.8 2.3 0.48 10.3 0.2 2.1 3 0 0 3 3 3 0 DDE domain Myosin_head PF00063.16 KFM11563.1 - 2.7e-151 504.9 0.0 2.3e-127 425.8 0.0 2.0 2 0 0 2 2 2 2 Myosin head (motor domain) ER-remodelling PF14755.1 KFM11564.1 - 0.14 12.2 4.7 0.16 12.0 3.3 1.3 1 0 0 1 1 1 0 Intracellular membrane remodeller TH1 PF04858.8 KFM11564.1 - 0.16 10.1 0.0 0.18 9.9 0.0 1.0 1 0 0 1 1 1 0 TH1 protein SH2 PF00017.19 KFM11565.1 - 0.00087 19.0 0.0 0.00097 18.8 0.0 1.1 1 0 0 1 1 1 1 SH2 domain Trm56 PF01994.11 KFM11565.1 - 0.11 12.2 0.0 0.11 12.2 0.0 1.0 1 0 0 1 1 1 0 tRNA ribose 2'-O-methyltransferase, aTrm56 Carb_anhydrase PF00194.16 KFM11566.1 - 2.1e-54 184.1 0.0 2.2e-26 92.3 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic-type carbonic anhydrase DUF1049 PF06305.6 KFM11566.1 - 0.056 12.9 0.1 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Aph-1 PF06105.7 KFM11567.1 - 2.6e-81 272.3 9.8 2.9e-81 272.2 6.8 1.0 1 0 0 1 1 1 1 Aph-1 protein Adeno_E1B_55K PF01696.12 KFM11567.1 - 0.26 9.6 0.6 0.36 9.2 0.4 1.1 1 0 0 1 1 1 0 Adenovirus EB1 55K protein / large t-antigen Tropomyosin PF00261.15 KFM11568.1 - 5.2e-104 346.5 87.7 5e-99 330.2 42.3 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.2 KFM11568.1 - 2.1e-40 137.8 75.7 1.9e-35 121.8 31.9 3.3 1 1 2 3 3 3 3 Tropomyosin like Laminin_II PF06009.7 KFM11568.1 - 1.2e-07 31.5 31.6 0.00022 21.0 3.2 3.5 1 1 3 4 4 4 3 Laminin Domain II TMF_DNA_bd PF12329.3 KFM11568.1 - 0.0013 18.4 28.7 0.0036 17.0 6.4 6.2 1 1 4 6 6 5 2 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.4 KFM11568.1 - 0.0017 18.2 66.6 0.008 16.0 19.1 2.3 2 0 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 KFM11568.1 - 0.0017 16.2 66.9 0.0037 15.0 18.6 2.3 1 1 1 2 2 2 1 Myosin tail IncA PF04156.9 KFM11568.1 - 0.0032 17.0 57.6 0.1 12.2 4.5 3.2 1 1 2 3 3 3 1 IncA protein Reo_sigmaC PF04582.7 KFM11568.1 - 0.006 15.7 6.4 0.13 11.4 0.4 2.1 2 0 0 2 2 2 2 Reovirus sigma C capsid protein AAA_13 PF13166.1 KFM11568.1 - 0.0068 14.9 49.0 0.12 10.8 11.8 2.0 1 1 1 2 2 2 2 AAA domain Laminin_I PF06008.9 KFM11568.1 - 0.042 13.1 50.8 0.083 12.1 5.8 3.1 1 1 3 4 4 4 0 Laminin Domain I WES_acyltransf PF03007.11 KFM11568.1 - 0.071 12.6 1.2 0.5 9.8 0.8 2.1 1 1 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain SlyX PF04102.7 KFM11568.1 - 0.16 12.3 0.2 0.16 12.3 0.1 6.1 2 2 4 6 6 6 0 SlyX Baculo_PEP_C PF04513.7 KFM11568.1 - 0.18 11.6 11.5 2.3 8.0 2.4 3.1 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.6 KFM11568.1 - 0.23 11.2 51.9 0.17 11.6 4.4 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) MscS_porin PF12795.2 KFM11568.1 - 0.35 10.1 42.2 1.3 8.2 7.3 3.1 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain ERM PF00769.14 KFM11568.1 - 0.53 9.7 72.4 0.028 13.9 13.0 3.1 1 1 3 4 4 4 0 Ezrin/radixin/moesin family Fib_alpha PF08702.5 KFM11568.1 - 0.7 10.0 32.2 1.1 9.4 3.4 3.2 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family MAD PF05557.8 KFM11568.1 - 0.87 7.5 59.7 25 2.7 8.6 2.3 1 1 1 2 2 2 0 Mitotic checkpoint protein APG6 PF04111.7 KFM11568.1 - 0.89 8.5 61.0 0.24 10.3 10.5 2.9 1 1 3 4 4 4 0 Autophagy protein Apg6 DUF4200 PF13863.1 KFM11568.1 - 1 9.2 68.5 0.047 13.6 21.2 4.0 1 1 2 3 3 2 0 Domain of unknown function (DUF4200) gpW PF02831.10 KFM11568.1 - 1.1 8.8 5.5 5.4 6.6 0.0 3.2 3 0 0 3 3 3 0 gpW WEMBL PF05701.6 KFM11568.1 - 1.2 7.4 71.5 5.8e+02 -1.4 49.6 3.6 1 1 0 1 1 1 0 Weak chloroplast movement under blue light DUF4164 PF13747.1 KFM11568.1 - 2.3 8.4 53.2 0.038 14.1 7.5 4.9 1 1 5 6 6 6 0 Domain of unknown function (DUF4164) ADIP PF11559.3 KFM11568.1 - 2.3 8.0 51.6 0.89 9.4 3.6 4.1 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding Spectrin PF00435.16 KFM11568.1 - 2.6 8.3 48.0 0.21 11.9 2.8 4.4 1 1 3 4 4 4 0 Spectrin repeat Flagellin_N PF00669.15 KFM11568.1 - 3.5 7.4 13.9 1.6 8.5 3.3 3.4 1 1 4 5 5 5 0 Bacterial flagellin N-terminal helical region GAS PF13851.1 KFM11568.1 - 3.8 6.6 62.7 5.5 6.1 9.4 3.2 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding GTPase_Cys_C PF12631.2 KFM11568.1 - 4.1 7.8 18.4 1.2 9.6 2.8 4.3 2 2 3 5 5 5 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE DUF869 PF05911.6 KFM11568.1 - 4.8 5.2 55.2 3.4 5.8 21.8 2.3 1 1 0 2 2 2 0 Plant protein of unknown function (DUF869) TMCO5 PF14992.1 KFM11568.1 - 7.5 5.6 55.5 0.062 12.4 7.8 3.0 1 1 2 3 3 3 0 TMCO5 family Talin_middle PF09141.5 KFM11569.1 - 2.6e-73 245.0 7.1 2.6e-73 245.0 4.9 15.6 10 4 4 15 15 15 6 Talin, middle domain VBS PF08913.5 KFM11569.1 - 2e-68 228.4 11.1 2.9e-65 218.1 1.9 12.2 8 2 1 10 10 10 5 Vinculin Binding Site I_LWEQ PF01608.12 KFM11569.1 - 3e-55 186.3 204.8 3.3e-46 156.9 10.5 18.6 10 6 7 20 20 20 9 I/LWEQ domain FERM_N PF09379.5 KFM11569.1 - 2.4e-30 104.3 0.6 1.4e-26 92.3 0.8 3.2 2 0 0 2 2 2 2 FERM N-terminal domain FERM_M PF00373.13 KFM11569.1 - 1.6e-25 89.6 0.0 1.6e-25 89.6 0.0 4.5 5 0 0 5 5 5 1 FERM central domain IRS PF02174.12 KFM11569.1 - 3e-05 23.5 0.0 7.5e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 PTB domain (IRS-1 type) ACBP PF00887.14 KFM11569.1 - 0.00036 20.1 0.0 0.0019 17.8 0.0 2.3 1 0 0 1 1 1 1 Acyl CoA binding protein Toxin_52 PF15605.1 KFM11569.1 - 0.53 10.2 11.2 0.55 10.1 0.0 6.0 6 0 0 6 6 6 0 Putative toxin 52 Avidin PF01382.12 KFM11570.1 - 4e-18 65.7 0.0 4.5e-18 65.6 0.0 1.0 1 0 0 1 1 1 1 Avidin family Avidin PF01382.12 KFM11571.1 - 3e-25 88.7 0.2 3.4e-25 88.5 0.1 1.0 1 0 0 1 1 1 1 Avidin family Avidin PF01382.12 KFM11572.1 - 1.1e-30 106.2 0.2 1.2e-30 106.0 0.2 1.0 1 0 0 1 1 1 1 Avidin family SPDY PF03771.11 KFM11572.1 - 0.015 14.8 0.2 0.032 13.7 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF317) Avidin PF01382.12 KFM11573.1 - 2.6e-36 124.3 4.4 3e-36 124.1 3.0 1.0 1 0 0 1 1 1 1 Avidin family DUF608 PF04685.8 KFM11574.1 - 9.2e-150 498.3 5.4 9.2e-150 498.3 3.8 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF608 GBA2_N PF12215.3 KFM11574.1 - 2.4e-81 273.1 0.0 3.3e-81 272.7 0.0 1.2 1 0 0 1 1 1 1 beta-Glucocerebrosidase 2 N terminal Bac_rhamnosid PF05592.6 KFM11574.1 - 0.018 13.2 0.4 0.027 12.7 0.3 1.2 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase Rgp1 PF08737.5 KFM11575.1 - 1e-58 199.3 2.2 1.2e-39 136.5 0.2 3.1 2 1 1 3 3 3 3 Rgp1 PSP94 PF05825.6 KFM11576.1 - 2.7e-10 40.3 5.8 3.6e-10 39.9 4.0 1.1 1 0 0 1 1 1 1 Beta-microseminoprotein (PSP-94) VWC PF00093.13 KFM11576.1 - 0.0051 16.8 5.0 0.011 15.8 3.5 1.7 1 1 0 1 1 1 1 von Willebrand factor type C domain TILa PF12714.2 KFM11576.1 - 0.12 12.2 8.5 0.3 10.8 5.9 1.8 1 1 0 1 1 1 0 TILa domain ANF_receptor PF01094.23 KFM11577.1 - 1.7e-21 76.4 0.1 2e-21 76.1 0.1 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.1 KFM11577.1 - 0.037 13.3 0.0 0.042 13.1 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein DUF3522 PF12036.3 KFM11578.1 - 0.055 13.2 0.3 0.082 12.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3522) Nucleos_tra2_C PF07662.8 KFM11580.1 - 1.8e-70 236.6 4.5 1.8e-70 236.6 3.1 1.4 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Gate PF07670.9 KFM11580.1 - 7.4e-08 32.2 6.4 7.4e-08 32.2 4.4 2.8 2 1 0 2 2 2 1 Nucleoside recognition DUF1767 PF08585.7 KFM11581.1 - 3.2e-25 88.2 1.3 5.6e-25 87.4 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1767) Kinesin PF00225.18 KFM11582.1 - 9.1e-110 366.4 1.4 9.1e-110 366.4 1.0 3.3 3 1 0 3 3 3 1 Kinesin motor domain Tropomyosin_1 PF12718.2 KFM11582.1 - 0.00097 19.0 2.6 0.00097 19.0 1.8 8.6 6 1 2 8 8 8 1 Tropomyosin like ubiquitin PF00240.18 KFM11584.1 - 1.1e-12 47.0 0.5 2e-12 46.3 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 KFM11584.1 - 4.7e-07 29.4 0.3 1.3e-06 28.0 0.2 1.9 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.3 KFM11584.1 - 0.0002 20.9 0.1 0.00041 19.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 KFM11584.1 - 0.0093 15.8 0.1 0.019 14.8 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Clathrin-link PF09268.5 KFM11584.1 - 0.038 13.0 14.8 3.1 6.9 0.1 5.7 5 0 0 5 5 5 0 Clathrin, heavy-chain linker CUE PF02845.11 KFM11584.1 - 0.052 13.0 1.6 0.16 11.4 0.0 2.6 2 0 0 2 2 2 0 CUE domain DNA_ligase_A_N PF04675.9 KFM11584.1 - 0.11 12.2 0.1 0.48 10.2 0.0 1.9 2 0 0 2 2 2 0 DNA ligase N terminus SKI PF01202.17 KFM11585.1 - 8.8e-08 32.1 0.0 1.4e-07 31.5 0.0 1.3 1 1 0 1 1 1 1 Shikimate kinase FERM_M PF00373.13 KFM11586.1 - 1.6e-18 67.0 0.2 3.8e-18 65.8 0.0 1.7 2 0 0 2 2 2 1 FERM central domain FERM_C PF09380.5 KFM11586.1 - 1.8e-17 63.3 0.3 3.8e-17 62.2 0.2 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.5 KFM11586.1 - 8.2e-17 61.0 0.0 2.1e-16 59.7 0.0 1.8 1 0 0 1 1 1 1 FERM N-terminal domain FA PF08736.6 KFM11586.1 - 1.3e-16 60.0 3.6 2.5e-16 59.1 2.5 1.5 1 0 0 1 1 1 1 FERM adjacent (FA) Ras PF00071.17 KFM11587.1 - 1.5e-50 170.7 0.0 1.5e-50 170.7 0.0 1.9 2 0 0 2 2 2 1 Ras family Miro PF08477.8 KFM11587.1 - 1.2e-20 74.1 0.0 4.5e-20 72.3 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM11587.1 - 5e-16 58.4 0.5 1e-15 57.4 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFM11587.1 - 2.6e-07 30.5 0.8 6.7e-07 29.2 0.0 2.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFM11587.1 - 3.8e-05 23.1 1.8 5.3e-05 22.7 0.0 2.1 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFM11587.1 - 0.023 13.8 0.0 0.023 13.8 0.0 2.4 2 1 1 3 3 3 0 Gtr1/RagA G protein conserved region AAA_25 PF13481.1 KFM11587.1 - 0.12 11.8 0.3 0.41 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain Reo_sigmaC PF04582.7 KFM11587.1 - 0.15 11.1 2.1 0.23 10.6 1.0 1.5 1 1 0 1 1 1 0 Reovirus sigma C capsid protein AAA_33 PF13671.1 KFM11587.1 - 0.16 11.8 0.0 0.16 11.8 0.0 3.0 3 1 0 3 3 3 0 AAA domain TPR_MLP1_2 PF07926.7 KFM11587.1 - 3.1 7.5 35.8 11 5.8 10.5 2.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-Q PF13094.1 KFM11587.1 - 6.5 6.7 34.3 1.6 8.7 3.8 3.5 1 1 2 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Baculo_p24 PF05073.7 KFM11587.1 - 9.8 5.6 16.3 1.1 8.8 5.2 2.4 1 1 1 2 2 2 0 Baculovirus P24 capsid protein FUSC-like PF12805.2 KFM11587.1 - 9.9 4.9 10.7 0.13 11.2 1.5 2.0 2 1 0 2 2 2 0 FUSC-like inner membrane protein yccS TLE_N PF03920.10 KFM11590.1 - 2e-53 179.8 9.5 3e-53 179.2 6.6 1.2 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain WD40 PF00400.27 KFM11590.1 - 2.8e-30 103.0 24.5 4e-08 32.8 0.3 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KFM11590.1 - 0.061 11.6 0.0 1.4 7.1 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain Transketolase_N PF00456.16 KFM11590.1 - 0.065 12.0 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain Yae1_N PF09811.4 KFM11591.1 - 2.6e-20 71.6 64.3 1.5e+04 -24.9 44.6 5.7 1 1 0 1 1 1 0 Essential protein Yae1, N terminal TLE_N PF03920.10 KFM11592.1 - 1.8e-36 124.9 6.6 2.6e-36 124.4 4.6 1.3 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain WD40 PF00400.27 KFM11592.1 - 1.7e-31 106.9 22.8 3.8e-08 32.9 0.3 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KFM11592.1 - 0.031 12.5 0.0 1.3 7.2 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain Transketolase_N PF00456.16 KFM11592.1 - 0.067 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain Yae1_N PF09811.4 KFM11593.1 - 6.4e-29 99.1 97.1 1.5e+04 -57.8 67.3 8.2 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Yae1_N PF09811.4 KFM11594.1 - 2.6e-20 71.6 64.3 1.5e+04 -24.9 44.6 5.7 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Aminotran_5 PF00266.14 KFM11595.1 - 2e-59 201.2 0.0 2.2e-59 201.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V EGF_alliinase PF04863.8 KFM11595.1 - 0.16 11.9 0.8 0.33 10.9 0.6 1.5 1 0 0 1 1 1 0 Alliinase EGF-like domain LRR_6 PF13516.1 KFM11596.1 - 1.6e-08 33.7 5.5 0.07 13.2 0.0 5.8 6 0 0 6 6 6 2 Leucine Rich repeat LRR_4 PF12799.2 KFM11596.1 - 0.0077 15.8 1.3 1.6 8.4 0.1 3.3 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) ATG16 PF08614.6 KFM11596.1 - 0.6 9.9 11.0 0.27 11.0 6.0 1.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) G-alpha PF00503.15 KFM11597.1 - 7e-118 393.6 2.3 7.9e-118 393.5 1.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KFM11597.1 - 4.2e-11 42.3 0.2 2.1e-10 40.1 0.2 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KFM11599.1 - 3.6e-114 381.4 5.2 4.1e-114 381.2 3.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KFM11599.1 - 1.4e-11 43.9 1.1 2.7e-09 36.5 0.0 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 KFM11599.1 - 0.067 13.6 0.7 9.8 6.7 0.4 2.7 2 1 0 2 2 2 0 Miro-like protein LMSTEN PF07988.7 KFM11599.1 - 0.19 11.0 2.7 0.16 11.2 0.2 2.1 2 0 0 2 2 2 0 LMSTEN motif DHHA2 PF02833.9 KFM11600.1 - 0.0021 18.2 0.0 0.005 17.0 0.0 1.6 1 0 0 1 1 1 1 DHHA2 domain FUR PF01475.14 KFM11600.1 - 0.0068 16.3 0.2 0.14 12.1 0.0 2.2 1 1 1 2 2 2 1 Ferric uptake regulator family RPA_C PF08784.6 KFM11600.1 - 0.1 13.0 0.1 0.33 11.4 0.0 1.7 1 1 1 2 2 2 0 Replication protein A C terminal Ste50p-SAM PF09235.5 KFM11600.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.8 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Stork_head PF10264.4 KFM11600.1 - 0.11 12.6 0.2 0.46 10.6 0.0 2.0 1 1 1 2 2 2 0 Winged helix Storkhead-box1 domain BNIP2 PF12496.3 KFM11601.1 - 3.9e-45 153.1 3.4 5e-45 152.7 2.4 1.1 1 0 0 1 1 1 1 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 CRAL_TRIO_2 PF13716.1 KFM11601.1 - 6.8e-30 103.9 0.1 9.1e-30 103.5 0.1 1.1 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 KFM11601.1 - 5.3e-10 39.0 0.5 1e-09 38.1 0.3 1.3 1 1 0 1 1 1 1 CRAL/TRIO domain RRN3 PF05327.6 KFM11601.1 - 0.29 9.2 3.6 4.1 5.3 0.8 2.0 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Flavokinase PF01687.12 KFM11602.1 - 7.2e-28 96.9 0.0 7.8e-28 96.8 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase zf-CHC2 PF01807.15 KFM11602.1 - 0.053 13.0 0.2 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 CHC2 zinc finger CD20 PF04103.10 KFM11603.1 - 2.7e-06 27.3 5.3 4.9e-06 26.5 3.7 1.4 1 0 0 1 1 1 1 CD20-like family PID PF00640.18 KFM11604.1 - 1.2e-50 171.1 0.8 2.4e-50 170.1 0.6 1.6 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PDZ PF00595.19 KFM11604.1 - 8.3e-32 109.2 10.3 4.3e-17 62.0 0.7 3.2 3 0 0 3 3 3 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM11604.1 - 1.2e-07 31.4 0.0 1.6e-05 24.6 0.0 2.8 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.1 KFM11604.1 - 0.037 13.8 0.2 2.8 7.8 0.0 3.0 3 0 0 3 3 3 0 Tricorn protease PDZ domain PPTA PF01239.17 KFM11605.1 - 2.7e-30 102.4 9.9 3.6e-09 35.5 0.0 6.4 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat MAM PF00629.18 KFM11606.1 - 3.7e-136 449.3 0.1 2.8e-45 153.9 0.0 4.0 4 0 0 4 4 4 4 MAM domain CBM_4_9 PF02018.12 KFM11606.1 - 0.049 13.6 0.6 0.96 9.4 0.0 2.8 3 0 0 3 3 3 0 Carbohydrate binding domain Ion_trans PF00520.26 KFM11607.1 - 5.5e-11 42.0 11.7 5.5e-11 42.0 8.1 1.9 2 1 0 2 2 2 1 Ion transport protein G8 PF10162.4 KFM11608.1 - 1.1e-25 89.8 0.0 2.3e-25 88.8 0.0 1.6 1 0 0 1 1 1 1 G8 domain Methyltransf_13 PF08421.6 KFM11608.1 - 0.072 12.5 0.5 13 5.3 0.0 2.9 2 0 0 2 2 2 0 Putative zinc binding domain Abhydrolase_5 PF12695.2 KFM11609.1 - 3.5e-29 101.4 0.0 4.9e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFM11609.1 - 1.7e-15 57.5 0.1 1e-12 48.4 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFM11609.1 - 3.3e-08 33.3 0.0 0.00072 19.1 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFM11609.1 - 1.5e-07 30.8 0.0 1.7e-05 24.1 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 KFM11609.1 - 3.3e-05 23.2 0.0 5.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family UPF0227 PF05728.7 KFM11609.1 - 0.0019 17.9 0.0 0.045 13.4 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) FSH1 PF03959.8 KFM11609.1 - 0.0034 16.8 0.0 0.0051 16.2 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF818 PF05677.7 KFM11609.1 - 0.0038 16.0 0.1 0.0053 15.5 0.1 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_2 PF02230.11 KFM11609.1 - 0.011 15.1 0.0 0.063 12.7 0.0 2.0 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase RNA_ligase PF09414.5 KFM11609.1 - 0.091 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 RNA ligase Hydrolase_4 PF12146.3 KFM11609.1 - 0.092 12.6 0.0 0.31 10.9 0.0 1.9 2 0 0 2 2 2 0 Putative lysophospholipase DUF2039 PF10217.4 KFM11610.1 - 9.6e-25 86.4 11.4 1e-24 86.3 7.9 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) Cript PF10235.4 KFM11610.1 - 0.024 14.9 6.7 0.024 14.9 4.7 1.8 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT Stc1 PF12898.2 KFM11610.1 - 0.03 14.3 7.1 0.063 13.3 5.0 1.4 1 1 0 1 1 1 0 Stc1 domain DUF2256 PF10013.4 KFM11610.1 - 0.17 11.6 0.2 0.17 11.6 0.2 3.2 2 2 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C3HC4_3 PF13920.1 KFM11610.1 - 0.29 10.8 13.8 7.3 6.3 2.3 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ADK_lid PF05191.9 KFM11610.1 - 0.48 10.1 11.4 2.5 7.8 0.0 3.1 2 1 1 3 3 3 0 Adenylate kinase, active site lid Zn-ribbon_8 PF09723.5 KFM11610.1 - 0.84 9.6 10.1 0.66 9.9 0.4 2.8 1 1 2 3 3 3 0 Zinc ribbon domain zinc-ribbons_6 PF07191.7 KFM11610.1 - 3.8 7.3 10.1 43 3.9 7.0 2.0 1 1 0 1 1 1 0 zinc-ribbons zf-RING_5 PF14634.1 KFM11610.1 - 4.9 6.9 14.6 5.6 6.7 5.8 2.8 1 1 1 2 2 2 0 zinc-RING finger domain zf-ribbon_3 PF13248.1 KFM11610.1 - 5.4 6.3 7.5 2.2 7.6 1.9 2.4 2 1 0 2 2 2 0 zinc-ribbon domain Amidohydro_1 PF01979.15 KFM11611.1 - 2.2e-43 149.1 0.0 2.6e-43 148.9 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KFM11611.1 - 1.7e-06 28.3 0.0 0.001 19.2 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 KFM11611.1 - 2.6e-05 23.6 0.3 0.0035 16.6 0.0 2.3 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 KFM11611.1 - 0.0011 18.7 0.0 0.0025 17.6 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase zf-A20 PF01754.11 KFM11612.1 - 7.4e-13 47.8 7.7 2.2e-12 46.3 5.3 1.9 1 0 0 1 1 1 1 A20-like zinc finger zf-AN1 PF01428.11 KFM11612.1 - 1.6e-12 47.1 6.9 1.6e-12 47.1 4.8 1.9 2 0 0 2 2 2 1 AN1-like Zinc finger TFIIA PF03153.8 KFM11612.1 - 0.077 12.8 1.4 0.076 12.9 1.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lamp PF01299.12 KFM11612.1 - 6 5.9 9.2 8.2 5.4 6.4 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) zf-C3HC4_3 PF13920.1 KFM11612.1 - 6.3 6.5 9.1 3.6 7.3 0.1 3.1 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM11612.1 - 7.2 6.4 9.3 51 3.6 0.0 2.7 2 0 0 2 2 2 0 zinc-RING finger domain Aldedh PF00171.17 KFM11613.1 - 3.5e-181 602.5 0.0 3.9e-181 602.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Annexin PF00191.15 KFM11614.1 - 1.3e-88 290.9 14.0 4e-24 84.3 0.4 4.1 4 0 0 4 4 4 4 Annexin DrrA_P4M PF14860.1 KFM11614.1 - 0.012 15.3 3.6 2.2 8.0 0.3 2.7 2 1 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain TPR_8 PF13181.1 KFM11614.1 - 0.061 13.1 1.7 18 5.3 0.1 4.6 5 1 0 5 5 5 0 Tetratricopeptide repeat Yae1_N PF09811.4 KFM11616.1 - 8.2e-18 63.6 55.1 1.5e+04 -16.1 38.2 5.1 1 1 0 1 1 1 0 Essential protein Yae1, N terminal zf-C4 PF00105.13 KFM11617.1 - 2.1e-33 114.3 12.3 5e-33 113.1 8.5 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 KFM11617.1 - 1.8e-29 102.3 1.7 1.8e-29 102.3 1.2 2.0 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor Ion_trans PF00520.26 KFM11618.1 - 5.5e-08 32.2 10.0 1.5e-07 30.8 6.9 1.8 1 1 0 1 1 1 1 Ion transport protein WPP PF13943.1 KFM11618.1 - 0.066 13.4 0.3 0.13 12.4 0.2 1.5 1 0 0 1 1 1 0 WPP domain N2227 PF07942.7 KFM11619.1 - 4.8e-112 373.3 0.2 5.8e-112 373.0 0.1 1.1 1 0 0 1 1 1 1 N2227-like protein RhoGAP PF00620.22 KFM11619.1 - 0.02 14.4 0.4 1.1 8.8 0.2 2.3 1 1 1 2 2 2 0 RhoGAP domain Methyltransf_23 PF13489.1 KFM11619.1 - 0.026 14.2 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KFM11619.1 - 0.027 14.9 0.0 0.09 13.2 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_24 PF13578.1 KFM11619.1 - 0.064 14.1 0.0 0.15 12.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 KFM11619.1 - 0.067 13.6 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain AAA_18 PF13238.1 KFM11620.1 - 3.8e-15 56.3 0.0 6.7e-15 55.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFM11620.1 - 1.1e-07 32.7 0.2 4e-07 30.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 KFM11620.1 - 0.01 15.8 0.1 0.14 12.1 0.0 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.1 KFM11620.1 - 0.051 13.4 0.0 0.21 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain CPT PF07931.7 KFM11620.1 - 0.17 11.5 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein APS_kinase PF01583.15 KFM11620.1 - 0.2 11.2 0.4 1.6 8.3 0.0 2.4 3 0 0 3 3 3 0 Adenylylsulphate kinase Ank_2 PF12796.2 KFM11621.1 - 4.3e-35 119.9 9.1 2.1e-18 66.4 0.3 2.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFM11621.1 - 1.2e-23 82.6 3.6 5.8e-11 42.2 0.3 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 KFM11621.1 - 4.1e-19 67.3 1.2 7.6e-08 31.7 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KFM11621.1 - 5.8e-17 61.7 0.8 9.4e-09 35.5 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) SH3_1 PF00018.23 KFM11621.1 - 5.9e-17 60.7 0.0 1.1e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFM11621.1 - 3e-15 55.5 0.1 4.9e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Ank_3 PF13606.1 KFM11621.1 - 5.9e-15 53.8 0.3 0.0017 18.4 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat SH3_2 PF07653.12 KFM11621.1 - 2.9e-13 49.0 0.0 6e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Peptidase_S8 PF00082.17 KFM11622.1 - 3.8e-58 196.8 3.1 5.9e-58 196.2 2.2 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 KFM11622.1 - 6.5e-32 109.1 0.0 1.3e-31 108.1 0.0 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain GF_recep_IV PF14843.1 KFM11622.1 - 4.5e-14 52.2 90.0 8.4e-11 41.6 25.0 3.9 1 1 2 3 3 3 3 Growth factor receptor domain IV PLAC PF08686.6 KFM11622.1 - 2.3e-13 50.1 7.7 2.3e-13 50.1 5.4 4.8 5 0 0 5 5 5 1 PLAC (protease and lacunin) domain VSP PF03302.8 KFM11622.1 - 1.3e-07 30.5 79.8 0.00048 18.8 10.9 5.6 2 1 4 6 6 6 4 Giardia variant-specific surface protein Yae1_N PF09811.4 KFM11625.1 - 7.2e-11 41.4 28.6 0.34 10.4 19.8 3.1 1 1 0 1 1 1 1 Essential protein Yae1, N terminal PIP5K PF01504.13 KFM11626.1 - 1.2e-80 270.2 0.2 1.6e-80 269.8 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Frataxin_Cyay PF01491.11 KFM11627.1 - 4.8e-34 116.4 0.0 5.7e-34 116.1 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain PDZ PF00595.19 KFM11628.1 - 1.9e-41 140.1 4.4 8e-14 51.5 0.1 3.4 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM11628.1 - 8.1e-15 54.4 0.6 0.00013 21.7 0.0 3.6 3 0 0 3 3 3 3 PDZ domain Guanylate_kin PF00625.16 KFM11628.1 - 8.3e-12 44.9 0.1 1.7e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Guanylate kinase SH3_2 PF07653.12 KFM11628.1 - 2.1e-08 33.5 0.4 4.7e-07 29.1 0.0 3.2 4 0 0 4 4 4 1 Variant SH3 domain SH3_1 PF00018.23 KFM11628.1 - 0.00018 20.8 0.0 0.0029 16.9 0.0 3.0 2 0 0 2 2 2 1 SH3 domain LIM PF00412.17 KFM11629.1 - 1.4e-24 85.8 21.9 2.4e-14 53.1 5.3 2.3 2 0 0 2 2 2 2 LIM domain Homeobox PF00046.24 KFM11629.1 - 7.6e-20 70.2 2.4 1.3e-19 69.5 1.6 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFM11629.1 - 0.00016 21.2 0.5 0.00032 20.3 0.3 1.6 1 1 0 1 1 1 1 Homeobox KN domain DUF2175 PF09943.4 KFM11629.1 - 0.0015 18.5 2.8 0.0023 17.9 0.6 2.2 1 1 1 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2175) Sulfolobus_pRN PF05584.6 KFM11629.1 - 0.13 12.2 0.0 0.37 10.7 0.0 1.8 2 0 0 2 2 2 0 Sulfolobus plasmid regulatory protein HypA PF01155.14 KFM11629.1 - 5.4 6.7 6.6 0.51 10.0 0.3 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_2 PF13240.1 KFM11629.1 - 5.9 6.5 6.6 9.5 5.8 0.1 3.4 4 0 0 4 4 4 0 zinc-ribbon domain DUF581 PF04570.9 KFM11629.1 - 7.5 5.9 14.0 4.4 6.6 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF581) Choline_transpo PF04515.7 KFM11630.1 - 7.2e-131 435.8 32.1 7.2e-131 435.8 22.2 2.1 2 0 0 2 2 2 2 Plasma-membrane choline transporter DUF3753 PF12575.3 KFM11630.1 - 0.055 13.2 0.5 0.055 13.2 0.4 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3753) Acyl-CoA_dh_1 PF00441.19 KFM11631.1 - 1.9e-40 138.4 3.6 2.8e-40 137.8 2.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KFM11631.1 - 2e-28 99.2 0.2 3.7e-28 98.3 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KFM11631.1 - 2.2e-22 78.2 0.1 4.5e-22 77.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KFM11631.1 - 3.3e-20 72.7 4.3 5.2e-20 72.0 3.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 KFM11631.1 - 4.5e-05 22.9 0.0 0.0001 21.8 0.0 1.6 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Prenyltrans PF00432.16 KFM11632.1 - 5.8e-70 230.4 10.5 8e-15 54.1 0.1 5.9 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KFM11632.1 - 2.8e-29 101.8 0.0 7.3e-18 65.0 0.0 3.2 2 1 1 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 KFM11632.1 - 5.4e-11 42.4 0.0 4.3e-09 36.3 0.0 3.1 4 1 0 4 4 4 1 Prenyltransferase-like BAG PF02179.11 KFM11632.1 - 0.027 14.5 0.0 0.34 11.0 0.0 2.2 2 0 0 2 2 2 0 BAG domain Adenine_deam_C PF13382.1 KFM11632.1 - 0.074 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Adenine deaminase C-terminal domain Acetyltransf_1 PF00583.19 KFM11633.1 - 2.3e-14 53.1 0.1 3.2e-14 52.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KFM11633.1 - 1.4e-08 34.3 0.1 2.1e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KFM11633.1 - 2.6e-07 30.7 0.0 3.9e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFM11633.1 - 5.2e-05 23.3 0.0 6.9e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFM11633.1 - 0.0014 18.4 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CDC73 PF05179.9 KFM11634.1 - 2.2e-115 384.7 1.2 2.4e-115 384.6 0.0 1.6 2 0 0 2 2 2 1 RNA pol II accessory factor, Cdc73 family Galactosyl_T PF01762.16 KFM11635.1 - 6.7e-66 221.6 0.0 9.8e-66 221.0 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Glutaredoxin PF00462.19 KFM11636.1 - 9.5e-18 63.9 0.1 1.2e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.1 KFM11636.1 - 0.003 17.3 0.0 0.0045 16.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain DUF836 PF05768.9 KFM11636.1 - 0.019 15.2 0.0 0.026 14.7 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.1 KFM11636.1 - 0.024 14.8 0.5 0.035 14.3 0.4 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KFM11636.1 - 0.03 14.3 0.2 0.069 13.1 0.2 1.6 1 1 0 1 1 1 0 Thioredoxin-like DUF2117 PF09890.4 KFM11636.1 - 0.078 12.1 0.0 0.092 11.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2117) TraF PF13728.1 KFM11636.1 - 0.12 11.7 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein ArsC PF03960.10 KFM11636.1 - 0.13 12.3 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 ArsC family TROVE PF05731.6 KFM11637.1 - 6e-108 361.0 0.4 7.4e-108 360.7 0.3 1.1 1 0 0 1 1 1 1 TROVE domain DUF2201 PF09967.4 KFM11637.1 - 7e-06 26.0 0.6 1.3e-05 25.2 0.1 1.6 2 0 0 2 2 2 1 VWA-like domain (DUF2201) VWA_CoxE PF05762.9 KFM11637.1 - 0.1 11.7 1.3 0.29 10.2 0.6 2.0 2 1 0 2 2 2 0 VWA domain containing CoxE-like protein VWA_2 PF13519.1 KFM11637.1 - 0.13 12.3 0.1 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain Peptidase_C12 PF01088.16 KFM11638.1 - 1.3e-56 191.1 0.9 1.7e-56 190.8 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 RGS PF00615.14 KFM11639.1 - 1.4e-40 138.1 7.7 1.5e-40 137.9 5.3 1.0 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS PF00615.14 KFM11640.1 - 1e-38 132.0 2.3 1.2e-38 131.8 1.6 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS-like PF09128.6 KFM11640.1 - 0.013 15.0 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain RGS PF00615.14 KFM11641.1 - 9.3e-37 125.7 2.0 1.3e-36 125.3 1.4 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS PF00615.14 KFM11642.1 - 1.7e-37 128.1 3.2 2e-37 127.8 2.2 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain Gag_p19 PF02228.11 KFM11642.1 - 0.094 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Major core protein p19 NAD_binding_10 PF13460.1 KFM11643.1 - 4.7e-10 39.7 0.1 5.4e-10 39.5 0.1 1.1 1 0 0 1 1 1 1 NADH(P)-binding Sushi PF00084.15 KFM11644.1 - 1.5e-50 169.3 61.8 6.6e-10 39.1 2.8 7.2 7 1 1 8 8 8 6 Sushi domain (SCR repeat) Lectin_C PF00059.16 KFM11644.1 - 4.4e-22 78.7 2.2 2.6e-21 76.2 1.5 2.4 1 0 0 1 1 1 1 Lectin C-type domain EGF PF00008.22 KFM11644.1 - 5e-07 29.5 13.3 8.9e-07 28.7 5.9 4.3 2 0 0 2 2 2 1 EGF-like domain EGF_2 PF07974.8 KFM11644.1 - 1.4e-05 25.1 8.3 0.00056 20.0 5.8 4.1 1 0 0 1 1 1 1 EGF-like domain cEGF PF12662.2 KFM11644.1 - 0.00051 19.6 45.1 0.0017 17.9 2.2 7.9 7 0 0 7 7 7 4 Complement Clr-like EGF-like EGF_3 PF12947.2 KFM11644.1 - 0.0084 16.0 2.6 0.0084 16.0 1.8 5.5 8 0 0 8 8 8 1 EGF domain Eclosion PF04736.7 KFM11644.1 - 0.04 13.3 35.3 2.2 7.8 0.5 6.9 7 0 0 7 7 7 0 Eclosion hormone Glug PF07581.7 KFM11644.1 - 0.095 12.9 5.6 2e+02 2.5 0.0 5.5 6 0 0 6 6 6 0 The GLUG motif HRM PF02793.17 KFM11644.1 - 0.28 11.2 46.9 1.7 8.7 1.0 6.9 7 0 0 7 7 7 0 Hormone receptor domain bZIP_1 PF00170.16 KFM11645.1 - 3.1e-10 39.8 12.7 6.2e-10 38.8 8.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFM11645.1 - 5.3e-06 26.1 13.0 5.3e-06 26.1 9.0 2.3 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 KFM11645.1 - 0.0017 18.5 8.2 0.0017 18.5 5.7 2.9 3 0 0 3 3 3 1 bZIP Maf transcription factor adh_short PF00106.20 KFM11646.1 - 6.1e-13 49.0 0.3 1.4e-07 31.6 0.1 2.5 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.5 KFM11646.1 - 0.00056 19.6 0.2 0.0013 18.3 0.0 1.7 2 0 0 2 2 2 1 KR domain Pkinase_Tyr PF07714.12 KFM11648.1 - 4.7e-86 288.0 0.0 6e-86 287.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM11648.1 - 5.4e-45 153.5 0.0 9e-45 152.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain F5_F8_type_C PF00754.20 KFM11648.1 - 0.00011 22.0 0.0 0.0021 17.9 0.0 2.3 2 0 0 2 2 2 1 F5/8 type C domain Herpes_gE PF02480.11 KFM11648.1 - 0.029 12.6 0.0 0.042 12.1 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Shisa PF13908.1 KFM11648.1 - 0.063 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator F5_F8_type_C PF00754.20 KFM11649.1 - 1.2e-15 57.4 0.0 1.5e-15 57.1 0.0 1.0 1 0 0 1 1 1 1 F5/8 type C domain UDPGP PF01704.13 KFM11650.1 - 3.5e-88 295.9 0.0 4.5e-88 295.5 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Pkinase PF00069.20 KFM11651.1 - 4.1e-35 121.1 0.0 5e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM11651.1 - 3.5e-17 62.3 0.1 4.6e-17 61.9 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RRM_5 PF13893.1 KFM11651.1 - 2e-08 33.9 0.0 3.5e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFM11651.1 - 5.8e-08 32.2 0.0 1.1e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kinase-like PF14531.1 KFM11651.1 - 3.3e-07 29.5 0.0 4.4e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RRM_6 PF14259.1 KFM11651.1 - 1.2e-06 28.4 0.0 2.8e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) APH PF01636.18 KFM11651.1 - 0.00054 19.7 0.1 0.00092 19.0 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KFM11651.1 - 0.0025 17.1 0.0 0.0051 16.1 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KFM11651.1 - 0.0045 16.0 0.1 0.0077 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KFM11651.1 - 0.097 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF4628 PF15429.1 KFM11652.1 - 3e-47 161.3 1.5 3.3e-47 161.1 1.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4628) zf-C2H2_4 PF13894.1 KFM11653.1 - 0.048 13.9 2.1 0.19 12.1 1.5 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger UBN2_3 PF14244.1 KFM11653.1 - 0.069 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type PID PF00640.18 KFM11654.1 - 9.4e-22 77.4 1.3 9.4e-22 77.4 0.9 1.8 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) PID_2 PF14719.1 KFM11654.1 - 3.1 7.4 6.1 0.22 11.1 0.3 1.9 2 0 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) CECR6_TMEM121 PF14997.1 KFM11655.1 - 3.2e-60 203.0 11.6 5.8e-60 202.2 8.0 1.4 1 0 0 1 1 1 1 CECR6/TMEM121 family EIID-AGA PF03613.9 KFM11655.1 - 0.0053 15.7 4.4 0.034 13.0 3.0 2.0 1 1 0 1 1 1 1 PTS system mannose/fructose/sorbose family IID component DUF996 PF06195.8 KFM11655.1 - 0.27 11.2 12.9 1.4 8.9 2.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF996) DUF4509 PF14970.1 KFM11656.1 - 1.1e-55 188.2 0.3 1.2e-55 188.0 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4509) LIM PF00412.17 KFM11657.1 - 3.1e-16 59.1 7.1 3.5e-16 58.9 4.9 1.1 1 0 0 1 1 1 1 LIM domain PhnA_Zn_Ribbon PF08274.7 KFM11657.1 - 0.0036 17.0 1.3 0.17 11.7 0.1 2.4 2 0 0 2 2 2 1 PhnA Zinc-Ribbon zf-DNA_Pol PF08996.5 KFM11657.1 - 0.0046 16.3 1.4 0.0063 15.8 0.9 1.1 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger zf-C2H2_4 PF13894.1 KFM11657.1 - 0.013 15.7 2.9 4.7 7.7 0.0 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger DUF329 PF03884.9 KFM11657.1 - 0.034 13.7 6.5 0.46 10.0 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF329) TNFR_c6 PF00020.13 KFM11657.1 - 0.051 13.6 3.7 0.099 12.7 0.4 2.3 2 0 0 2 2 2 0 TNFR/NGFR cysteine-rich region Metallothio_Pro PF02069.11 KFM11657.1 - 0.061 13.1 4.8 0.05 13.4 1.4 1.9 1 1 1 2 2 2 0 Prokaryotic metallothionein DUF2321 PF10083.4 KFM11657.1 - 0.077 12.4 1.4 0.078 12.4 0.7 1.2 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) Rep_fac-A_C PF08646.5 KFM11657.1 - 0.33 10.6 2.8 0.42 10.3 1.9 1.2 1 0 0 1 1 1 0 Replication factor-A C terminal domain zinc_ribbon_4 PF13717.1 KFM11657.1 - 0.56 9.9 5.6 5 6.8 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 KFM11657.1 - 0.67 9.5 5.5 5.5 6.6 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain UPF0547 PF10571.4 KFM11657.1 - 0.99 9.1 6.6 5.4 6.8 4.6 2.3 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 zf-ribbon_3 PF13248.1 KFM11657.1 - 1.1 8.5 6.5 1.7 7.9 0.1 2.6 2 1 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 KFM11657.1 - 1.1 9.2 6.4 5 7.1 0.1 2.4 2 1 0 2 2 2 0 Zinc ribbon domain Mu-like_Com PF10122.4 KFM11657.1 - 1.5 7.9 8.3 2.6 7.1 0.8 2.2 2 0 0 2 2 2 0 Mu-like prophage protein Com Sgf11 PF08209.6 KFM11657.1 - 1.6 8.1 6.7 1.7 8.0 0.8 2.4 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zinc-ribbons_6 PF07191.7 KFM11657.1 - 4.6 7.0 6.8 23 4.8 4.8 2.0 1 1 0 1 1 1 0 zinc-ribbons LIM PF00412.17 KFM11658.1 - 2.2e-25 88.4 15.2 8.5e-15 54.5 2.9 2.2 2 0 0 2 2 2 2 LIM domain Metallothio_Pro PF02069.11 KFM11658.1 - 0.033 13.9 9.0 0.85 9.4 0.2 2.6 3 0 0 3 3 3 0 Prokaryotic metallothionein zf-CCHC_5 PF14787.1 KFM11658.1 - 0.034 13.6 0.1 0.034 13.6 0.1 3.4 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger TNFR_c6 PF00020.13 KFM11658.1 - 0.035 14.1 10.1 0.98 9.5 0.6 3.3 3 0 0 3 3 3 0 TNFR/NGFR cysteine-rich region zf-FPG_IleRS PF06827.9 KFM11658.1 - 0.035 13.7 11.3 2.3 7.9 0.1 3.6 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS Pea-VEAacid PF08111.6 KFM11658.1 - 0.068 13.2 2.6 12 6.2 0.1 2.7 2 0 0 2 2 2 0 Pea-VEAacid family E6 PF00518.12 KFM11658.1 - 0.098 13.0 2.7 4.6 7.6 0.3 2.4 2 1 0 2 2 2 0 Early Protein (E6) zf-DNA_Pol PF08996.5 KFM11658.1 - 0.14 11.4 5.0 0.42 9.9 0.2 2.1 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger DUF329 PF03884.9 KFM11658.1 - 0.2 11.2 15.7 2.6 7.6 1.9 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF329) DUF1610 PF07754.6 KFM11658.1 - 1.5 9.0 12.1 1.3 9.2 0.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) zf-ribbon_3 PF13248.1 KFM11658.1 - 4.2 6.7 14.8 2.1 7.6 0.1 3.9 3 1 0 3 3 3 0 zinc-ribbon domain Pacs-1 PF10254.4 KFM11659.1 - 8.5e-200 663.6 3.9 8.5e-200 663.6 2.7 1.6 2 0 0 2 2 2 1 PACS-1 cytosolic sorting protein Longin PF13774.1 KFM11660.1 - 3e-25 87.5 0.1 3.4e-25 87.4 0.0 1.0 1 0 0 1 1 1 1 Regulated-SNARE-like domain EGF PF00008.22 KFM11661.1 - 3.1e-115 375.3 219.3 2.1e-09 37.1 6.3 15.3 15 0 0 15 15 15 15 EGF-like domain EGF_CA PF07645.10 KFM11661.1 - 7.5e-49 163.4 214.0 5.8e-08 32.6 5.2 15.2 10 5 5 15 15 15 15 Calcium-binding EGF domain hEGF PF12661.2 KFM11661.1 - 3.7e-39 130.1 138.0 0.00061 19.6 1.6 16.2 15 0 0 15 15 15 13 Human growth factor-like EGF EGF_2 PF07974.8 KFM11661.1 - 2.4e-21 75.5 246.8 0.0019 18.2 8.5 15.4 15 0 0 15 15 15 14 EGF-like domain EGF_3 PF12947.2 KFM11661.1 - 6.9e-15 54.7 205.8 2.9e-05 23.9 2.6 16.2 13 3 2 15 15 15 13 EGF domain cEGF PF12662.2 KFM11661.1 - 1e-11 44.2 167.7 0.0084 15.7 0.4 17.0 15 2 0 15 15 15 11 Complement Clr-like EGF-like FXa_inhibition PF14670.1 KFM11661.1 - 1.8e-08 34.3 199.2 0.041 14.0 2.7 15.2 6 4 9 15 15 15 8 Coagulation Factor Xa inhibitory site Laminin_EGF PF00053.19 KFM11661.1 - 0.24 11.3 199.0 3.4 7.6 4.9 14.5 5 4 9 14 14 14 0 Laminin EGF-like (Domains III and V) Guanylate_kin PF00625.16 KFM11662.1 - 3.7e-35 121.0 0.2 3.8e-32 111.2 0.0 2.0 2 0 0 2 2 2 2 Guanylate kinase DUF258 PF03193.11 KFM11662.1 - 0.011 14.8 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 PKD PF00801.15 KFM11663.1 - 7.4e-08 32.0 0.0 3.9e-07 29.7 0.0 2.2 2 0 0 2 2 2 1 PKD domain BNR PF02012.15 KFM11663.1 - 3.5e-05 23.0 4.9 1.4 9.0 0.2 5.1 4 0 0 4 4 4 2 BNR/Asp-box repeat PH PF00169.24 KFM11664.1 - 2.4e-27 95.1 1.5 1.2e-13 51.1 1.1 2.9 2 0 0 2 2 2 2 PH domain ERM PF00769.14 KFM11664.1 - 1.5e-05 24.7 8.1 1.5e-05 24.7 5.6 2.2 3 0 0 3 3 3 1 Ezrin/radixin/moesin family PH_9 PF15410.1 KFM11664.1 - 4.9e-05 23.4 1.0 1.1 9.4 0.3 4.1 2 2 0 2 2 2 2 Pleckstrin homology domain GAS PF13851.1 KFM11664.1 - 0.19 10.9 17.1 0.54 9.4 11.9 1.7 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 KFM11664.1 - 0.53 9.2 13.2 1.4 7.8 9.1 1.7 1 0 0 1 1 1 0 Autophagy protein Apg6 Prefoldin_2 PF01920.15 KFM11664.1 - 0.79 9.5 17.7 0.63 9.8 3.1 3.2 3 0 0 3 3 3 0 Prefoldin subunit V_ATPase_I PF01496.14 KFM11664.1 - 3.6 5.3 4.7 5.9 4.6 3.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LIM PF00412.17 KFM11665.1 - 7.5e-40 134.8 43.8 7.9e-14 51.4 2.1 4.3 4 0 0 4 4 4 4 LIM domain VHP PF02209.14 KFM11665.1 - 5.6e-17 61.1 2.3 9.3e-17 60.4 1.6 1.4 1 0 0 1 1 1 1 Villin headpiece domain TPR_12 PF13424.1 KFM11666.1 - 7.9e-20 70.5 50.5 1.2e-05 25.1 2.7 9.1 7 3 2 10 10 10 8 Tetratricopeptide repeat TPR_11 PF13414.1 KFM11666.1 - 9.6e-06 25.1 48.8 0.025 14.2 1.5 8.6 7 2 3 10 10 10 3 TPR repeat TPR_10 PF13374.1 KFM11666.1 - 9.8e-05 22.1 13.6 3.4 7.7 0.1 7.6 8 0 0 8 8 8 2 Tetratricopeptide repeat SH3_1 PF00018.23 KFM11666.1 - 0.00011 21.4 0.4 0.00044 19.5 0.0 2.1 2 0 0 2 2 2 1 SH3 domain TPR_2 PF07719.12 KFM11666.1 - 0.00012 21.6 44.8 0.31 11.0 0.3 11.2 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_16 PF13432.1 KFM11666.1 - 0.00017 22.1 24.5 0.15 12.8 0.1 7.6 7 1 1 8 8 8 1 Tetratricopeptide repeat SH3_2 PF07653.12 KFM11666.1 - 0.001 18.5 0.0 0.003 16.9 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain TPR_1 PF00515.23 KFM11666.1 - 0.0026 17.2 37.9 0.22 11.2 0.0 9.8 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFM11666.1 - 0.0083 15.8 38.1 0.17 11.7 0.2 11.5 11 1 2 13 13 13 1 Tetratricopeptide repeat SH3_9 PF14604.1 KFM11666.1 - 0.045 13.3 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain Rad21_Rec8 PF04824.11 KFM11666.1 - 0.055 12.6 0.6 0.27 10.4 0.0 2.4 2 0 0 2 2 2 0 Conserved region of Rad21 / Rec8 like protein TPR_21 PF09976.4 KFM11666.1 - 0.09 12.7 2.4 0.13 12.1 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFM11666.1 - 1.2 9.9 20.5 34 5.4 0.2 7.5 8 1 1 9 9 8 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFM11666.1 - 1.7 8.6 23.7 0.26 11.1 0.1 8.0 11 0 0 11 11 10 0 Tetratricopeptide repeat ACOX PF01756.14 KFM11667.1 - 2.3e-46 157.5 0.0 3.6e-46 156.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 KFM11667.1 - 8.9e-13 47.5 0.2 1.6e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 KFM11667.1 - 3.9e-08 33.5 0.1 6.6e-07 29.5 0.1 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 KFM11667.1 - 1.6e-06 28.4 0.0 3.5e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal AdoMet_MTase PF07757.8 KFM11668.1 - 2.7e-41 140.1 0.1 5.5e-41 139.2 0.1 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 KFM11668.1 - 0.0052 16.5 0.0 0.0093 15.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KFM11668.1 - 0.0082 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_31 PF13847.1 KFM11668.1 - 0.0084 15.7 0.0 0.024 14.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 KFM11668.1 - 0.026 14.2 0.1 0.082 12.5 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KFM11668.1 - 0.069 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain 7tm_1 PF00001.16 KFM11670.1 - 3.4e-39 134.5 19.5 4.4e-39 134.1 13.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PGG PF13962.1 KFM11670.1 - 0.027 14.0 1.0 0.027 14.0 0.7 2.6 2 1 1 3 3 3 0 Domain of unknown function gpUL132 PF11359.3 KFM11670.1 - 1.5 8.0 7.4 0.42 9.9 1.9 2.1 2 0 0 2 2 2 0 Glycoprotein UL132 Git3 PF11710.3 KFM11670.1 - 1.7 8.1 14.7 1.4 8.4 8.6 1.8 1 1 1 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 Peptidase_M14 PF00246.19 KFM11671.1 - 1.2e-77 261.2 0.0 1.6e-77 260.8 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Fz PF01392.17 KFM11671.1 - 5e-19 68.7 3.5 5e-19 68.7 2.4 1.7 2 0 0 2 2 2 1 Fz domain CarboxypepD_reg PF13620.1 KFM11671.1 - 5.1e-15 55.2 0.0 9.2e-15 54.4 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 KFM11671.1 - 2.9e-08 33.6 0.0 5.2e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4480) Glypican PF01153.14 KFM11671.1 - 0.0072 14.9 1.6 0.011 14.3 1.1 1.1 1 0 0 1 1 1 1 Glypican AstE_AspA PF04952.9 KFM11671.1 - 0.11 11.4 0.0 2.3 7.0 0.1 2.6 2 1 0 2 2 2 0 Succinylglutamate desuccinylase / Aspartoacylase family 7tm_1 PF00001.16 KFM11672.1 - 1.5e-80 270.0 4.8 2e-80 269.6 3.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM11672.1 - 2.1e-10 40.1 13.1 1.4e-07 30.9 1.9 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 KFM11672.1 - 5e-07 29.1 10.7 0.00019 20.6 0.8 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.4 KFM11672.1 - 7.4e-06 25.2 15.9 7.4e-06 25.2 3.0 2.5 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx Alpha-2-MRAP_C PF06401.6 KFM11673.1 - 5.2e-101 336.9 29.0 5.2e-101 336.9 20.1 1.5 2 0 0 2 2 2 1 Alpha-2-macroglobulin RAP, C-terminal domain Alpha-2-MRAP_N PF06400.6 KFM11673.1 - 1.2e-29 102.4 23.6 3.9e-29 100.7 3.2 3.5 3 1 0 3 3 3 3 Alpha-2-macroglobulin RAP, N-terminal domain Med30 PF11315.3 KFM11673.1 - 0.0053 16.8 3.7 0.0053 16.8 2.5 2.1 1 1 1 2 2 2 1 Mediator complex subunit 30 PriCT_2 PF08707.6 KFM11673.1 - 0.029 14.2 0.5 0.37 10.6 0.1 2.3 2 0 0 2 2 2 0 Primase C terminal 2 (PriCT-2) DNA_ligase_A_C PF04679.10 KFM11673.1 - 4.3 7.8 5.5 17 5.9 0.1 3.0 3 2 0 3 3 3 0 ATP dependent DNA ligase C terminal region Spectrin PF00435.16 KFM11673.1 - 5.8 7.2 19.4 3.4 8.0 4.0 2.9 3 1 0 3 3 3 0 Spectrin repeat IRS PF02174.12 KFM11674.1 - 8.5e-09 34.9 0.0 2e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 PTB domain (IRS-1 type) Trypsin PF00089.21 KFM11675.1 - 1.9e-73 246.7 0.6 2.6e-73 246.2 0.4 1.2 1 0 0 1 1 1 1 Trypsin Kringle PF00051.13 KFM11675.1 - 3.5e-26 91.0 1.3 3.5e-26 91.0 0.9 2.8 2 1 0 3 3 3 1 Kringle domain fn2 PF00040.14 KFM11675.1 - 1.5e-12 47.3 6.0 1.5e-12 47.3 4.1 3.6 3 0 0 3 3 3 1 Fibronectin type II domain EGF PF00008.22 KFM11675.1 - 8.6e-09 35.1 32.0 2.7e-06 27.2 7.6 3.7 3 0 0 3 3 3 2 EGF-like domain fn1 PF00039.13 KFM11675.1 - 1.5e-06 27.9 1.5 1.5e-06 27.9 1.1 3.6 3 0 0 3 3 3 1 Fibronectin type I domain EGF_2 PF07974.8 KFM11675.1 - 0.09 12.9 34.4 0.032 14.3 7.9 4.2 3 0 0 3 3 3 0 EGF-like domain hEGF PF12661.2 KFM11675.1 - 5.5 7.2 18.8 0.091 12.8 1.9 4.1 3 0 0 3 3 3 0 Human growth factor-like EGF RBD PF02196.10 KFM11676.1 - 1.2e-35 121.1 0.2 2.1e-19 69.0 0.0 2.8 3 0 0 3 3 3 2 Raf-like Ras-binding domain RGS PF00615.14 KFM11676.1 - 6.4e-29 100.4 3.8 1.2e-28 99.6 2.6 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain PDZ PF00595.19 KFM11676.1 - 8.8e-14 51.4 0.1 1.1e-12 47.9 0.0 2.9 3 1 1 4 4 4 1 PDZ domain (Also known as DHR or GLGF) GoLoco PF02188.12 KFM11676.1 - 1.8e-09 36.6 0.2 1.8e-09 36.6 0.1 1.9 2 0 0 2 2 2 1 GoLoco motif PID PF00640.18 KFM11676.1 - 1.8e-05 24.7 0.1 4.6e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) TUG-UBL1 PF11470.3 KFM11676.1 - 0.00052 19.8 0.0 0.092 12.6 0.0 3.4 4 0 0 4 4 4 1 GLUT4 regulating protein TUG PDZ_2 PF13180.1 KFM11676.1 - 0.00071 19.4 0.1 0.0041 16.9 0.0 2.3 2 0 0 2 2 2 1 PDZ domain Myb_DNA-bind_4 PF13837.1 KFM11677.1 - 1.4e-11 44.3 1.3 1.4e-11 44.3 0.9 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain GPI PF06560.6 KFM11677.1 - 0.092 11.7 0.1 0.2 10.6 0.1 1.5 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) MADF_DNA_bdg PF10545.4 KFM11677.1 - 0.14 12.3 0.2 0.14 12.3 0.1 2.4 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like TipAS PF07739.8 KFM11677.1 - 2.7 8.3 6.5 0.53 10.6 0.3 2.2 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain Pkinase PF00069.20 KFM11678.1 - 6.6e-60 202.4 0.0 8.6e-60 202.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM11678.1 - 4.1e-34 117.8 0.0 5.7e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.14 KFM11678.1 - 1.1e-21 77.1 0.1 2.5e-21 75.9 0.1 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain Kinase-like PF14531.1 KFM11678.1 - 0.00017 20.6 0.0 0.00027 20.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like UDPG_MGDP_dh_C PF03720.10 KFM11678.1 - 0.077 13.1 0.0 0.31 11.2 0.0 2.0 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Nop14 PF04147.7 KFM11679.1 - 1.6e-254 846.7 37.0 1.8e-254 846.6 25.7 1.0 1 0 0 1 1 1 1 Nop14-like family DUF2810 PF10928.3 KFM11679.1 - 0.014 15.1 0.2 2.3 8.0 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2810) Mem_trans PF03547.13 KFM11679.1 - 8.7 4.5 5.2 0.71 8.1 0.0 1.7 2 0 0 2 2 2 0 Membrane transport protein MFS_1 PF07690.11 KFM11681.1 - 4.4e-39 134.1 46.4 5.9e-33 114.0 17.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFM11681.1 - 1.8e-11 43.3 10.7 1.8e-11 43.3 7.4 2.6 2 2 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KFM11681.1 - 3.5e-06 25.5 3.5 3.5e-06 25.5 2.4 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Abhydro_lipase PF04083.11 KFM11681.1 - 0.08 12.3 0.0 0.21 10.9 0.0 1.8 1 1 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Aldolase_II PF00596.16 KFM11682.1 - 5.8e-44 149.8 0.1 8.6e-44 149.3 0.1 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain PH PF00169.24 KFM11683.1 - 1.1e-14 54.4 0.2 2.1e-14 53.6 0.1 1.5 1 0 0 1 1 1 1 PH domain SH2 PF00017.19 KFM11683.1 - 4.8e-06 26.2 0.0 1.1e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 SH2 domain PH_6 PF15406.1 KFM11683.1 - 0.0039 17.2 0.0 0.0088 16.0 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain TMEM171 PF15471.1 KFM11683.1 - 1.2 7.8 4.1 2.3 6.9 2.8 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 EABR PF12180.3 KFM11684.1 - 4.7e-18 64.2 3.8 4.7e-18 64.2 2.6 2.6 2 0 0 2 2 2 1 TSG101 and ALIX binding domain of CEP55 FlxA PF14282.1 KFM11684.1 - 0.0025 17.7 6.0 0.0025 17.7 4.2 5.9 1 1 3 5 5 5 1 FlxA-like protein DUF1192 PF06698.6 KFM11684.1 - 0.005 16.6 14.8 0.065 13.0 0.3 4.7 4 1 0 4 4 4 2 Protein of unknown function (DUF1192) Octopine_DH PF02317.12 KFM11684.1 - 0.35 10.5 6.1 0.11 12.1 0.3 2.4 2 1 1 3 3 3 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Tropomyosin_1 PF12718.2 KFM11684.1 - 0.96 9.2 56.3 0.59 9.9 11.3 5.1 2 1 2 5 5 5 0 Tropomyosin like ATG16 PF08614.6 KFM11684.1 - 1.5 8.6 55.2 0.54 10.0 13.8 4.1 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) Spc7 PF08317.6 KFM11684.1 - 3.6 6.1 50.4 0.092 11.3 10.6 3.5 3 1 1 4 4 4 0 Spc7 kinetochore protein zf-RING_2 PF13639.1 KFM11686.1 - 4.2e-14 52.0 8.0 6.8e-14 51.4 4.5 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFM11686.1 - 2.7e-10 40.1 7.2 5.7e-10 39.0 5.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM11686.1 - 7.7e-10 38.2 6.4 1.4e-09 37.4 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM11686.1 - 1.1e-09 37.8 5.8 1.9e-09 37.0 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM11686.1 - 4.5e-09 35.8 6.6 8.3e-09 35.0 4.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 KFM11686.1 - 3.2e-06 26.6 3.8 8.5e-06 25.2 2.7 1.7 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 KFM11686.1 - 5.4e-06 26.4 1.5 1e-05 25.5 1.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger Rtf2 PF04641.7 KFM11686.1 - 5.6e-06 25.7 0.4 8.2e-06 25.2 0.3 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_UBOX PF13445.1 KFM11686.1 - 2.9e-05 23.6 2.5 0.00017 21.1 1.8 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KFM11686.1 - 0.00058 19.6 9.9 0.013 15.3 6.9 2.6 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 KFM11686.1 - 0.0011 18.4 4.2 0.0022 17.5 0.6 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-UDP PF14569.1 KFM11686.1 - 0.028 14.1 3.3 0.028 14.1 2.3 2.0 1 1 1 2 2 2 0 Zinc-binding RING-finger DUF1272 PF06906.6 KFM11686.1 - 0.11 12.3 5.8 0.27 11.1 4.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) zf-P11 PF03854.9 KFM11686.1 - 0.13 11.7 7.2 0.043 13.2 2.3 2.0 2 0 0 2 2 2 0 P-11 zinc finger zf-RING_6 PF14835.1 KFM11686.1 - 0.16 11.7 8.9 0.15 11.8 4.2 2.3 2 1 1 3 3 2 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 KFM11686.1 - 0.21 11.4 3.9 0.45 10.3 2.7 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.2 KFM11686.1 - 0.29 11.0 7.4 0.099 12.4 1.7 2.1 1 1 1 2 2 2 0 Double zinc ribbon FYVE PF01363.16 KFM11686.1 - 0.49 10.3 9.2 0.15 11.9 1.3 2.5 1 1 1 2 2 2 0 FYVE zinc finger zf-Nse PF11789.3 KFM11686.1 - 0.52 9.8 5.6 2.2 7.8 3.9 2.0 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zinc-ribbons_6 PF07191.7 KFM11686.1 - 1.1 9.1 6.9 4 7.3 4.8 2.0 1 1 0 1 1 1 0 zinc-ribbons FANCL_C PF11793.3 KFM11686.1 - 1.1 9.2 8.0 4.5 7.2 3.9 2.6 2 1 0 2 2 1 0 FANCL C-terminal domain DUF329 PF03884.9 KFM11686.1 - 3.3 7.3 7.4 3.4 7.2 0.4 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF329) zf-MIZ PF02891.15 KFM11686.1 - 3.9 7.0 9.4 55 3.3 0.1 2.3 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger Zn-ribbon_8 PF09723.5 KFM11686.1 - 5.5 7.0 6.6 3.5 7.6 2.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain IBR PF01485.16 KFM11686.1 - 8.1 6.4 9.7 60 3.6 6.6 2.6 1 1 1 2 2 2 0 IBR domain zf-RING_2 PF13639.1 KFM11687.1 - 3.9e-14 52.2 6.4 6.9e-14 51.4 4.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFM11687.1 - 2.9e-10 39.9 7.2 5.8e-10 39.0 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM11687.1 - 7.6e-10 38.3 6.4 1.4e-09 37.4 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM11687.1 - 1.1e-09 37.8 5.8 1.9e-09 37.0 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM11687.1 - 4.6e-09 35.8 6.6 8.4e-09 35.0 4.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 KFM11687.1 - 2.8e-06 26.7 3.6 7.5e-06 25.4 2.6 1.7 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 KFM11687.1 - 3.9e-06 26.8 0.8 8.9e-06 25.7 0.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KFM11687.1 - 3.1e-05 23.5 2.5 0.00018 21.1 1.8 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KFM11687.1 - 0.00067 19.4 10.0 0.013 15.3 7.0 2.5 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 KFM11687.1 - 0.0011 18.4 4.2 0.0022 17.5 0.6 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Rtf2 PF04641.7 KFM11687.1 - 0.0031 16.7 3.4 0.0044 16.2 2.0 1.6 1 1 0 1 1 1 1 Rtf2 RING-finger zf-RING_6 PF14835.1 KFM11687.1 - 0.01 15.6 5.0 0.091 12.5 3.6 2.1 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-UDP PF14569.1 KFM11687.1 - 0.011 15.4 6.2 0.012 15.3 1.5 2.2 2 0 0 2 2 2 0 Zinc-binding RING-finger DUF1272 PF06906.6 KFM11687.1 - 0.12 12.2 5.8 0.27 11.0 4.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) zf-P11 PF03854.9 KFM11687.1 - 0.12 11.8 7.2 0.043 13.2 2.3 2.1 2 0 0 2 2 2 0 P-11 zinc finger zf-Apc11 PF12861.2 KFM11687.1 - 0.18 11.6 3.7 0.36 10.6 2.5 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 KFM11687.1 - 0.24 11.4 5.6 4.6 7.2 3.9 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain FYVE PF01363.16 KFM11687.1 - 0.36 10.7 9.0 2.2 8.2 4.6 2.5 1 1 1 2 2 2 0 FYVE zinc finger DZR PF12773.2 KFM11687.1 - 0.41 10.5 7.8 0.094 12.5 1.7 2.1 1 1 0 1 1 1 0 Double zinc ribbon zf-Nse PF11789.3 KFM11687.1 - 0.81 9.2 7.2 1.6 8.2 3.9 2.3 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zinc-ribbons_6 PF07191.7 KFM11687.1 - 1.4 8.7 7.2 5.4 6.8 5.1 1.9 1 1 0 1 1 1 0 zinc-ribbons DUF329 PF03884.9 KFM11687.1 - 3.4 7.2 7.4 3.5 7.2 0.4 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF329) Zn-ribbon_8 PF09723.5 KFM11687.1 - 4.8 7.2 7.3 3.5 7.6 2.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain IBR PF01485.16 KFM11687.1 - 5.5 6.9 9.0 33 4.4 5.9 2.4 1 1 1 2 2 2 0 IBR domain FYVE PF01363.16 KFM11688.1 - 1.5e-19 69.6 12.1 1.5e-19 69.6 8.4 3.2 3 1 0 3 3 3 1 FYVE zinc finger HLH PF00010.21 KFM11689.1 - 3.5e-10 39.4 3.9 5.9e-10 38.6 1.8 2.1 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain Anthrax_toxA PF03497.11 KFM11689.1 - 0.0021 17.8 6.1 0.3 10.8 0.8 2.1 1 1 1 2 2 2 2 Anthrax toxin LF subunit ATP-synt_ab_C PF00306.22 KFM11689.1 - 0.072 13.5 1.8 0.11 12.9 1.3 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta chain, C terminal domain HAUS-augmin3 PF14932.1 KFM11690.1 - 8.4e-70 234.8 24.5 8.4e-70 234.8 17.0 4.1 1 1 3 4 4 4 1 HAUS augmin-like complex subunit 3 Baculo_PEP_C PF04513.7 KFM11690.1 - 0.027 14.2 32.1 0.02 14.7 1.3 4.7 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2064 PF09837.4 KFM11690.1 - 1.4 8.5 4.8 1.7 8.2 0.1 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2064) DNA_pol_A PF00476.15 KFM11691.1 - 4.9e-75 252.5 1.8 6.7e-75 252.0 1.2 1.2 1 0 0 1 1 1 1 DNA polymerase family A DUF1830 PF08865.6 KFM11692.1 - 0.086 12.4 0.0 0.099 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1830) Acetyltransf_1 PF00583.19 KFM11693.1 - 6.8e-16 58.0 0.1 9.3e-16 57.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFM11693.1 - 3.5e-11 43.0 0.0 5e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFM11693.1 - 2.6e-08 33.9 0.2 4.5e-08 33.2 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KFM11693.1 - 6e-08 32.7 0.0 1.8e-07 31.1 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KFM11693.1 - 4.1e-07 29.7 0.1 1.3e-05 24.9 0.0 2.0 1 1 1 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 KFM11693.1 - 1.2e-05 25.5 0.1 1.6e-05 25.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KFM11693.1 - 0.00014 21.8 0.0 0.00018 21.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFM11693.1 - 0.0008 19.1 1.2 0.002 17.8 0.1 1.9 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.1 KFM11693.1 - 0.0015 18.3 0.1 0.029 14.2 0.0 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.1 KFM11693.1 - 0.11 13.0 0.1 0.35 11.4 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Neuropep_like PF15161.1 KFM11694.1 - 1.6e-28 97.9 0.1 2e-28 97.6 0.1 1.1 1 0 0 1 1 1 1 Neuropeptide-like Neuropep_like PF15161.1 KFM11696.1 - 1.1e-28 98.4 0.3 1.7e-28 97.8 0.2 1.3 1 0 0 1 1 1 1 Neuropeptide-like Shal-type PF11601.3 KFM11697.1 - 5.2 6.6 6.4 29 4.2 0.1 2.7 2 0 0 2 2 2 0 Shal-type voltage-gated potassium channels LETM1 PF07766.8 KFM11698.1 - 4.3e-114 380.1 7.7 4.3e-114 380.1 5.3 3.2 2 1 0 3 3 3 1 LETM1-like protein EF-hand_7 PF13499.1 KFM11698.1 - 6.3e-05 23.0 0.3 0.0036 17.4 0.0 3.3 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 KFM11698.1 - 0.0052 16.5 0.2 1.7 8.7 0.1 3.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.1 KFM11698.1 - 0.0085 15.6 1.1 0.079 12.5 0.0 2.9 3 0 0 3 3 3 1 EF-hand domain pair SAP PF02037.22 KFM11698.1 - 0.011 15.1 0.2 0.011 15.1 0.1 3.3 3 0 0 3 3 3 0 SAP domain EF-hand_1 PF00036.27 KFM11698.1 - 0.012 14.8 0.2 0.19 11.1 0.1 2.9 3 0 0 3 3 3 0 EF hand MinC_N PF05209.8 KFM11698.1 - 0.019 14.6 0.8 1 9.1 0.0 3.5 2 1 0 3 3 3 0 Septum formation inhibitor MinC, N-terminal domain EF-hand_5 PF13202.1 KFM11698.1 - 0.032 13.5 0.2 0.16 11.3 0.2 2.4 1 0 0 1 1 1 0 EF hand DUF3573 PF12097.3 KFM11698.1 - 0.044 12.3 4.3 3.4 6.1 2.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) Acetyltransf_11 PF13720.1 KFM11698.1 - 0.11 12.7 0.1 0.11 12.7 0.1 3.5 5 0 0 5 5 5 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Pkinase_Tyr PF07714.12 KFM11699.1 - 4.3e-104 347.1 0.0 6.9e-104 346.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM11699.1 - 2e-48 164.7 0.0 2.8e-48 164.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain I-set PF07679.11 KFM11699.1 - 3.2e-36 123.0 0.0 2.1e-13 49.9 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM11699.1 - 4.7e-29 100.3 0.6 2.4e-09 37.1 0.0 3.7 4 0 0 4 4 3 3 Immunoglobulin domain ig PF00047.20 KFM11699.1 - 3.3e-23 81.5 3.2 1.5e-06 28.2 0.0 4.0 3 1 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 KFM11699.1 - 1.3e-21 76.8 1.6 1.7e-07 31.5 0.0 3.8 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 KFM11699.1 - 1.3e-15 57.3 4.8 4.2e-05 23.4 0.0 5.6 4 2 0 4 4 4 3 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM11699.1 - 0.00048 19.9 0.2 0.028 14.2 0.0 3.0 3 1 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Shisa PF13908.1 KFM11699.1 - 0.025 14.7 0.0 0.045 13.9 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator V-set_CD47 PF08204.6 KFM11699.1 - 0.04 13.6 0.9 1.2 8.8 0.0 3.0 3 1 0 3 3 3 0 CD47 immunoglobulin-like domain Orthoreo_P10 PF07204.6 KFM11699.1 - 0.079 12.7 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 FAM176 PF14851.1 KFM11699.1 - 0.098 12.3 0.0 1.8 8.2 0.0 2.2 2 0 0 2 2 2 0 FAM176 family RIO1 PF01163.17 KFM11699.1 - 0.15 11.3 0.1 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.1 KFM11699.1 - 0.22 10.4 0.1 0.48 9.3 0.0 1.5 2 0 0 2 2 2 0 Kinase-like TACC PF05010.9 KFM11703.1 - 2.5e-82 275.6 42.7 2.5e-82 275.6 29.6 1.8 2 0 0 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC) Tmpp129 PF10272.4 KFM11704.1 - 2.3e-131 437.7 5.3 2.6e-131 437.6 3.7 1.0 1 0 0 1 1 1 1 Putative transmembrane protein precursor C1_4 PF07975.7 KFM11704.1 - 0.025 14.5 1.6 0.025 14.5 1.1 2.6 1 1 1 2 2 2 0 TFIIH C1-like domain DUF3577 PF12101.3 KFM11704.1 - 0.04 13.8 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3577) dCMP_cyt_deam_1 PF00383.17 KFM11704.1 - 0.55 9.9 4.0 1.4 8.5 0.0 2.5 2 0 0 2 2 2 0 Cytidine and deoxycytidylate deaminase zinc-binding region zf-RING_2 PF13639.1 KFM11704.1 - 2.8 7.8 16.5 11 5.8 11.5 2.1 1 1 0 1 1 1 0 Ring finger domain SLBP_RNA_bind PF15247.1 KFM11705.1 - 8.7e-34 115.1 4.6 2.1e-33 113.8 3.2 1.6 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain SLBP_RNA_bind PF15247.1 KFM11706.1 - 1.6e-34 117.4 2.9 3.5e-34 116.4 2.0 1.5 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain Carla_C4 PF01623.12 KFM11706.1 - 0.1 12.3 0.2 0.19 11.5 0.2 1.5 1 0 0 1 1 1 0 Carlavirus putative nucleic acid binding protein Apelin PF15360.1 KFM11706.1 - 0.23 11.6 0.0 0.23 11.6 0.0 2.2 2 0 0 2 2 2 0 APJ endogenous ligand FAM53 PF15242.1 KFM11707.1 - 5.2e-123 410.5 23.5 6.6e-123 410.2 16.3 1.1 1 0 0 1 1 1 1 Family of FAM53 CLTH PF10607.4 KFM11710.1 - 4.8e-29 100.9 0.5 1.1e-28 99.8 0.3 1.6 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 KFM11710.1 - 0.0019 17.8 0.8 0.053 13.2 0.0 3.0 2 0 0 2 2 2 1 RING-type zinc-finger LisH PF08513.6 KFM11710.1 - 0.096 12.4 0.5 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 LisH 2-Hacid_dh_C PF02826.14 KFM11711.1 - 4.1e-57 192.1 0.0 5.9e-57 191.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFM11711.1 - 1.7e-28 98.7 0.0 2.1e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KFM11711.1 - 1.3e-05 25.1 0.0 2.7e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Cellsynth_D PF03500.8 KFM11711.1 - 0.02 14.5 0.0 0.067 12.8 0.0 1.8 2 0 0 2 2 2 0 Cellulose synthase subunit D XdhC_C PF13478.1 KFM11711.1 - 0.026 14.8 0.0 0.066 13.5 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain IL8 PF00048.15 KFM11712.1 - 1.5e-15 56.8 3.0 1.7e-15 56.7 2.1 1.0 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like BEN PF10523.4 KFM11713.1 - 1.8e-08 34.2 0.1 2.2e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 BEN domain SRCR PF00530.13 KFM11715.1 - 3.5e-126 412.2 47.4 1.5e-32 111.8 4.6 4.1 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 KFM11715.1 - 1.6e-19 69.9 23.6 4.5e-05 23.6 0.5 4.4 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain tRNA_Me_trans PF03054.11 KFM11715.1 - 0.044 12.3 3.8 10 4.5 0.0 3.8 4 0 0 4 4 4 0 tRNA methyl transferase DUF3027 PF11228.3 KFM11715.1 - 0.46 10.1 16.4 8 6.0 0.4 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3027) SapB_2 PF03489.12 KFM11715.1 - 1.4 8.9 17.6 23 5.1 0.3 6.2 7 0 0 7 7 7 0 Saposin-like type B, region 2 zf-H2C2_2 PF13465.1 KFM11716.1 - 2.1e-13 49.8 5.7 3.8e-07 30.0 0.8 2.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFM11716.1 - 3.2e-08 33.4 1.9 3.2e-08 33.4 1.3 1.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KFM11716.1 - 1.6e-05 24.8 0.0 2.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KFM11716.1 - 3.4e-05 23.8 1.4 3.4e-05 23.8 1.0 1.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM11716.1 - 7.4e-05 22.5 0.7 0.0001 22.0 0.5 1.3 1 0 0 1 1 1 1 C2H2-type zinc finger zf-met PF12874.2 KFM11716.1 - 0.00013 22.0 0.2 0.00018 21.6 0.1 1.2 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-BED PF02892.10 KFM11716.1 - 0.0091 15.7 0.3 0.0099 15.6 0.2 1.2 1 0 0 1 1 1 1 BED zinc finger C1_1 PF00130.17 KFM11716.1 - 0.086 12.5 0.5 0.089 12.5 0.3 1.2 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) BolA PF01722.13 KFM11716.1 - 0.1 12.5 0.1 0.11 12.4 0.1 1.1 1 0 0 1 1 1 0 BolA-like protein zf-H2C2_2 PF13465.1 KFM11717.1 - 2.1e-49 163.4 45.4 3.5e-09 36.5 0.2 7.0 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.21 KFM11717.1 - 1.5e-37 125.6 42.1 1.5e-06 28.2 0.4 7.1 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM11717.1 - 1.8e-24 84.1 38.9 6.3e-05 23.0 0.1 7.1 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM11717.1 - 3.3e-19 68.4 15.8 0.0017 18.4 0.1 7.0 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFM11717.1 - 3.8e-18 64.7 27.1 0.00052 19.8 0.2 7.1 7 0 0 7 7 7 6 C2H2-type zinc finger zf-met PF12874.2 KFM11717.1 - 6.6e-13 48.3 30.9 0.00051 20.1 0.3 6.4 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-CHY PF05495.7 KFM11717.1 - 2.4e-06 27.5 16.7 0.0031 17.6 0.8 3.3 2 1 1 3 3 3 3 CHY zinc finger XPA_N PF01286.13 KFM11717.1 - 1.6e-05 24.5 13.3 5.1 6.8 0.0 6.2 6 0 0 6 6 6 0 XPA protein N-terminal BolA PF01722.13 KFM11717.1 - 7.1e-05 22.6 1.5 0.34 10.9 0.0 2.8 2 1 0 3 3 3 2 BolA-like protein C1_1 PF00130.17 KFM11717.1 - 0.00011 21.8 19.8 0.064 12.9 2.0 4.4 2 2 2 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 KFM11717.1 - 0.00014 21.4 13.1 17 5.2 0.0 6.1 6 0 0 6 6 6 0 Prokaryotic RING finger family 1 PHF5 PF03660.9 KFM11717.1 - 0.0002 21.3 7.4 0.77 9.8 0.1 3.1 1 1 2 3 3 3 2 PHF5-like protein zf-Di19 PF05605.7 KFM11717.1 - 0.00031 20.8 29.7 0.079 13.0 0.8 4.4 2 1 1 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-trcl PF13451.1 KFM11717.1 - 0.0046 16.5 14.4 0.39 10.4 0.0 5.5 6 0 0 6 6 6 1 Probable zinc-binding domain FYDLN_acid PF09538.5 KFM11717.1 - 0.0053 17.3 4.0 3.3 8.3 0.2 4.0 1 1 2 3 3 3 0 Protein of unknown function (FYDLN_acid) C1_3 PF07649.7 KFM11717.1 - 0.0081 16.1 18.2 1.3 9.1 0.1 6.2 6 0 0 6 6 6 1 C1-like domain LIM PF00412.17 KFM11717.1 - 0.0097 15.9 17.0 0.26 11.3 0.7 4.7 1 1 2 4 4 4 1 LIM domain Zn-ribbon_8 PF09723.5 KFM11717.1 - 0.012 15.5 23.5 8.5 6.4 0.1 6.0 4 1 1 6 6 6 0 Zinc ribbon domain zf-C2HC_2 PF13913.1 KFM11717.1 - 0.027 14.1 24.2 1.8 8.3 0.1 6.5 6 1 0 6 6 6 0 zinc-finger of a C2HC-type DZR PF12773.2 KFM11717.1 - 0.028 14.2 15.7 3.6 7.4 3.6 3.7 1 1 1 2 2 2 0 Double zinc ribbon zf-H2C2_5 PF13909.1 KFM11717.1 - 0.044 14.0 0.7 0.044 14.0 0.5 6.4 7 3 0 7 7 4 0 C2H2-type zinc-finger domain DUF2225 PF09986.4 KFM11717.1 - 0.15 11.4 13.7 2.1 7.7 0.6 4.6 2 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) RRN7 PF11781.3 KFM11717.1 - 0.24 10.9 8.6 41 3.7 0.1 5.0 5 0 0 5 5 5 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-Sec23_Sec24 PF04810.10 KFM11717.1 - 0.27 10.8 8.9 7.3 6.2 0.0 4.9 5 1 0 6 6 6 0 Sec23/Sec24 zinc finger zf-AN1 PF01428.11 KFM11717.1 - 0.27 11.1 26.3 5.8 6.8 0.1 6.2 5 1 1 6 6 6 0 AN1-like Zinc finger PhnA_Zn_Ribbon PF08274.7 KFM11717.1 - 0.4 10.5 3.5 9.8 6.0 0.1 3.6 3 0 0 3 3 3 0 PhnA Zinc-Ribbon zf-RING_3 PF14369.1 KFM11717.1 - 0.45 10.5 0.1 0.45 10.5 0.1 5.4 6 0 0 6 6 6 0 zinc-finger DUF2180 PF09947.4 KFM11717.1 - 0.51 10.1 13.5 0.49 10.1 2.2 3.9 1 1 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2180) C1_2 PF03107.11 KFM11717.1 - 0.59 10.3 23.3 3.8 7.7 0.1 5.8 6 0 0 6 6 6 0 C1 domain Rad50_zn_hook PF04423.9 KFM11717.1 - 0.6 9.6 11.3 2.3 7.7 0.3 4.1 3 1 1 4 4 4 0 Rad50 zinc hook motif zf-HIT PF04438.11 KFM11717.1 - 0.78 9.4 27.2 0.28 10.8 0.5 5.8 6 0 0 6 6 6 0 HIT zinc finger Chordopox_RPO7 PF05864.7 KFM11717.1 - 1 9.5 6.8 1.6 8.8 0.0 3.8 5 0 0 5 5 4 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) zinc-ribbons_6 PF07191.7 KFM11717.1 - 1.2 9.0 15.0 9.6 6.0 0.1 5.5 3 2 3 6 6 6 0 zinc-ribbons GAGA PF09237.6 KFM11717.1 - 1.6 8.3 9.4 3.5 7.2 0.0 4.5 1 1 5 6 6 6 0 GAGA factor DUF2175 PF09943.4 KFM11717.1 - 1.9 8.5 9.7 28 4.8 0.0 4.9 6 0 0 6 6 5 0 Uncharacterized protein conserved in archaea (DUF2175) FYVE PF01363.16 KFM11717.1 - 1.9 8.4 25.2 4.1e+02 0.9 0.1 4.0 1 1 1 2 2 1 0 FYVE zinc finger zf-BED PF02892.10 KFM11717.1 - 2.8 7.7 31.2 2.8 7.7 0.5 6.0 2 1 4 6 6 6 0 BED zinc finger FdhE PF04216.7 KFM11717.1 - 3.3 7.3 18.5 2.2 7.9 1.8 3.0 1 1 1 2 2 2 0 Protein involved in formate dehydrogenase formation zf-FCS PF06467.9 KFM11717.1 - 3.4 7.3 21.0 2.9 7.6 1.6 5.6 4 2 2 6 6 6 0 MYM-type Zinc finger with FCS sequence motif Cript PF10235.4 KFM11717.1 - 4.4 7.7 15.2 2.1 8.7 0.1 4.3 3 1 1 4 4 3 0 Microtubule-associated protein CRIPT HNH PF01844.18 KFM11717.1 - 4.5 7.2 20.5 7.1 6.5 0.2 5.6 6 0 0 6 6 6 0 HNH endonuclease Zn_ribbon_recom PF13408.1 KFM11717.1 - 4.7 7.5 19.4 12 6.2 2.1 4.1 1 1 2 3 3 3 0 Recombinase zinc beta ribbon domain zf-C2H2_2 PF12756.2 KFM11717.1 - 5 7.2 22.7 13 5.9 0.0 5.5 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) Baculo_IE-1 PF05290.6 KFM11717.1 - 6.4 6.5 12.2 15 5.3 0.5 4.6 2 2 3 5 5 5 0 Baculovirus immediate-early protein (IE-0) DUF4428 PF14471.1 KFM11717.1 - 7.4 6.4 14.7 0.87 9.3 0.0 4.1 3 1 2 5 5 5 0 Domain of unknown function (DUF4428) CpXC PF14353.1 KFM11717.1 - 9.2 6.2 16.5 21 5.0 0.1 5.1 2 1 2 5 5 5 0 CpXC protein Rubredoxin PF00301.15 KFM11717.1 - 9.8 6.1 18.2 66 3.4 0.0 5.5 5 1 0 5 5 5 0 Rubredoxin SRCR PF00530.13 KFM11718.1 - 6.5e-130 424.1 49.7 5.6e-33 113.2 3.9 4.1 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 KFM11718.1 - 8.5e-20 70.8 13.8 0.00011 22.3 0.1 4.4 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain XylR_N PF06505.6 KFM11718.1 - 0.0027 17.0 0.7 1.9 7.9 0.0 3.7 4 0 0 4 4 4 1 Activator of aromatic catabolism Desulfoferrod_N PF06397.7 KFM11718.1 - 0.26 10.7 4.6 1.5 8.2 0.4 3.3 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain TYW3 PF02676.9 KFM11718.1 - 0.93 8.5 3.1 37 3.3 0.0 3.4 4 0 0 4 4 4 0 Methyltransferase TYW3 SRCR PF00530.13 KFM11719.1 - 8.1e-126 411.0 49.7 6.2e-33 113.0 3.3 4.3 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 KFM11719.1 - 1.6e-19 69.9 16.9 2.7e-05 24.3 0.2 4.4 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain Toxin_28 PF08115.6 KFM11719.1 - 0.5 10.0 8.9 2.2 7.9 0.1 4.3 3 0 0 3 3 3 0 SFI toxin family SRCR PF00530.13 KFM11720.1 - 4.1e-126 411.9 48.4 4.9e-32 110.1 3.1 4.1 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 KFM11720.1 - 4.4e-19 68.5 16.4 5.7e-05 23.2 0.3 4.4 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain Toxin_28 PF08115.6 KFM11720.1 - 0.14 11.7 6.1 7.5 6.2 0.2 3.8 3 0 0 3 3 3 0 SFI toxin family TYW3 PF02676.9 KFM11720.1 - 1.6 7.7 4.3 98 1.9 0.1 3.7 4 0 0 4 4 4 0 Methyltransferase TYW3 zf-H2C2_2 PF13465.1 KFM11721.1 - 1.1e-45 151.7 45.5 7.9e-10 38.5 2.3 7.0 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.21 KFM11721.1 - 2.2e-36 122.0 38.9 2.5e-07 30.6 0.5 6.1 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM11721.1 - 8.5e-26 88.3 44.6 2.5e-06 27.4 0.5 6.1 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM11721.1 - 4.4e-14 52.1 18.0 0.00059 19.8 0.1 6.0 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFM11721.1 - 2.6e-13 49.3 29.6 0.0052 16.6 0.1 6.6 6 2 0 6 6 6 5 C2H2-type zinc finger zf-trcl PF13451.1 KFM11721.1 - 3.9e-05 23.2 23.3 0.0029 17.2 1.2 4.5 3 1 1 4 4 4 2 Probable zinc-binding domain Zn-ribbon_8 PF09723.5 KFM11721.1 - 6.8e-05 22.7 27.4 0.52 10.3 2.1 5.7 3 2 1 4 4 4 3 Zinc ribbon domain C1_1 PF00130.17 KFM11721.1 - 0.00012 21.7 12.3 0.3 10.8 0.0 4.5 2 1 2 4 4 4 3 Phorbol esters/diacylglycerol binding domain (C1 domain) BolA PF01722.13 KFM11721.1 - 0.00015 21.6 3.1 2.5 8.1 0.0 3.7 1 1 2 3 3 3 2 BolA-like protein FYVE PF01363.16 KFM11721.1 - 0.00037 20.3 23.6 0.55 10.1 2.9 4.7 1 1 3 4 4 4 2 FYVE zinc finger XPA_N PF01286.13 KFM11721.1 - 0.0015 18.1 10.3 1.7 8.4 0.0 5.5 6 0 0 6 6 6 1 XPA protein N-terminal zf-met PF12874.2 KFM11721.1 - 0.0019 18.3 25.6 0.68 10.2 0.1 5.6 6 0 0 6 6 5 2 Zinc-finger of C2H2 type CpXC PF14353.1 KFM11721.1 - 0.0025 17.7 17.3 1.4 8.9 0.0 5.6 5 1 0 5 5 5 1 CpXC protein SprT-like PF10263.4 KFM11721.1 - 0.0026 17.4 17.7 0.19 11.3 1.3 3.1 1 1 2 3 3 3 2 SprT-like family zf-Di19 PF05605.7 KFM11721.1 - 0.0028 17.7 23.9 0.0085 16.2 2.7 4.2 1 1 4 5 5 5 2 Drought induced 19 protein (Di19), zinc-binding zf-LYAR PF08790.6 KFM11721.1 - 0.0062 16.2 8.4 2.3 8.0 0.1 5.5 6 0 0 6 6 6 1 LYAR-type C2HC zinc finger GAGA PF09237.6 KFM11721.1 - 0.0078 15.7 22.6 0.011 15.2 0.7 4.4 2 2 3 5 5 5 2 GAGA factor DZR PF12773.2 KFM11721.1 - 0.012 15.3 20.3 23 4.9 4.9 4.1 1 1 1 2 2 2 0 Double zinc ribbon DUF2321 PF10083.4 KFM11721.1 - 0.013 14.9 17.3 0.56 9.6 0.4 4.1 1 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2321) DUF329 PF03884.9 KFM11721.1 - 0.026 14.0 14.1 27 4.4 0.1 5.8 6 0 0 6 6 6 0 Domain of unknown function (DUF329) FYDLN_acid PF09538.5 KFM11721.1 - 0.032 14.8 10.7 15 6.1 0.0 4.9 1 1 3 5 5 5 0 Protein of unknown function (FYDLN_acid) zf-HYPF PF07503.7 KFM11721.1 - 0.042 13.2 16.9 1.5 8.3 2.6 5.6 5 1 0 5 5 5 0 HypF finger DUF2688 PF10892.3 KFM11721.1 - 0.044 13.4 2.8 7.6 6.2 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2688) zf-C2H2_2 PF12756.2 KFM11721.1 - 0.099 12.7 19.1 7.2 6.7 0.1 5.3 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) Prok-RING_4 PF14447.1 KFM11721.1 - 0.12 11.9 0.1 0.12 11.9 0.0 3.1 4 0 0 4 4 2 0 Prokaryotic RING finger family 4 zf-ISL3 PF14690.1 KFM11721.1 - 0.14 12.2 26.9 0.81 9.7 0.3 6.0 4 2 2 6 6 6 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HypA PF01155.14 KFM11721.1 - 0.19 11.4 16.5 2.6 7.7 0.4 3.7 2 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family C1_3 PF07649.7 KFM11721.1 - 0.27 11.3 15.3 6.1 6.9 0.1 5.4 6 0 0 6 6 5 0 C1-like domain C1_4 PF07975.7 KFM11721.1 - 0.29 11.1 18.7 17 5.5 1.4 5.1 1 1 4 6 6 6 0 TFIIH C1-like domain zf-AN1 PF01428.11 KFM11721.1 - 0.3 10.9 20.7 17 5.3 0.1 6.1 6 0 0 6 6 6 0 AN1-like Zinc finger Rad50_zn_hook PF04423.9 KFM11721.1 - 0.39 10.2 3.9 0.96 8.9 0.0 2.8 3 0 0 3 3 3 0 Rad50 zinc hook motif DUF2256 PF10013.4 KFM11721.1 - 0.4 10.4 23.4 0.79 9.5 0.0 5.7 5 1 1 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) RRN7 PF11781.3 KFM11721.1 - 0.47 9.9 16.9 7.4 6.1 0.1 5.7 6 0 0 6 6 6 0 RNA polymerase I-specific transcription initiation factor Rrn7 NADH-G_4Fe-4S_3 PF10588.4 KFM11721.1 - 0.56 9.4 7.4 2.3 7.5 0.4 3.4 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region TFIIS_C PF01096.13 KFM11721.1 - 0.59 9.8 20.9 15 5.3 0.1 6.0 6 0 0 6 6 6 0 Transcription factor S-II (TFIIS) zf-IS66 PF13005.2 KFM11721.1 - 0.68 9.9 21.2 5.5 7.0 0.0 6.0 6 0 0 6 6 6 0 zinc-finger binding domain of transposase IS66 FdhE PF04216.7 KFM11721.1 - 0.68 9.5 19.4 3.6 7.2 6.2 3.0 1 1 2 3 3 3 0 Protein involved in formate dehydrogenase formation PHF5 PF03660.9 KFM11721.1 - 1.3 9.0 6.4 1 9.4 0.1 2.7 1 1 1 3 3 3 0 PHF5-like protein zinc-ribbons_6 PF07191.7 KFM11721.1 - 1.5 8.7 16.5 9 6.1 0.7 4.5 1 1 3 4 4 4 0 zinc-ribbons zf-HIT PF04438.11 KFM11721.1 - 2 8.1 24.2 7.7 6.2 0.3 5.7 6 0 0 6 6 6 0 HIT zinc finger zf-RING_5 PF14634.1 KFM11721.1 - 2.2 8.0 15.8 13 5.5 0.1 4.3 3 1 0 3 3 3 0 zinc-RING finger domain DUF2039 PF10217.4 KFM11721.1 - 2.3 8.2 13.6 1.4 9.0 1.5 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2039) zf-RING_3 PF14369.1 KFM11721.1 - 3 7.9 19.4 7.4 6.6 0.1 5.5 6 0 0 6 6 6 0 zinc-finger DUF2225 PF09986.4 KFM11721.1 - 3.2 7.1 9.4 14 5.0 0.1 4.0 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) COX5B PF01215.14 KFM11721.1 - 5 6.8 14.5 7.3 6.2 0.2 5.1 1 1 5 6 6 6 0 Cytochrome c oxidase subunit Vb RNA_POL_M_15KD PF02150.11 KFM11721.1 - 7.7 6.2 16.8 0.71 9.6 0.4 4.7 5 1 0 5 5 4 0 RNA polymerases M/15 Kd subunit Elf1 PF05129.8 KFM11721.1 - 8.2 6.2 13.6 10 5.8 0.4 4.2 1 1 4 5 5 5 0 Transcription elongation factor Elf1 like zf-CSL PF05207.8 KFM11721.1 - 8.4 5.9 16.5 4.7 6.8 0.7 3.9 1 1 1 3 3 3 0 CSL zinc finger Vanabin-2 PF11437.3 KFM11722.1 - 2.1 8.4 16.9 4 7.4 8.2 2.2 1 1 1 2 2 2 0 Vanadium-binding protein 2 SRCR PF00530.13 KFM11723.1 - 2.8e-99 325.9 31.4 1.6e-31 108.5 0.8 4.1 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 KFM11723.1 - 2.2e-15 56.6 5.2 6e-05 23.2 0.0 3.6 3 0 0 3 3 3 3 Scavenger receptor cysteine-rich domain XylR_N PF06505.6 KFM11723.1 - 0.012 15.0 0.6 2.9 7.3 0.0 3.1 3 0 0 3 3 3 0 Activator of aromatic catabolism SCAN PF02023.12 KFM11724.1 - 6.5e-27 92.8 0.4 9e-27 92.3 0.3 1.2 1 0 0 1 1 1 1 SCAN domain zf-H2C2_2 PF13465.1 KFM11725.1 - 2.1e-89 289.7 81.2 7.1e-10 38.6 1.2 11.9 12 0 0 12 12 11 11 Zinc-finger double domain zf-C2H2 PF00096.21 KFM11725.1 - 2.5e-72 235.0 78.0 3.7e-08 33.2 1.4 11.1 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM11725.1 - 2.3e-48 158.9 69.0 5.9e-07 29.3 0.5 11.1 11 0 0 11 11 11 11 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM11725.1 - 1.5e-41 139.0 57.7 3.7e-05 23.4 0.1 11.2 11 0 0 11 11 11 11 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM11725.1 - 2.2e-25 88.1 25.4 0.0027 17.7 0.0 10.7 11 0 0 11 11 11 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM11725.1 - 9.1e-17 60.6 46.2 0.0054 16.8 0.3 10.2 10 0 0 10 10 10 6 Zinc-finger of C2H2 type C1_4 PF07975.7 KFM11725.1 - 1.1e-08 34.9 32.0 0.024 14.6 1.1 7.6 1 1 7 8 8 8 3 TFIIH C1-like domain Zn-ribbon_8 PF09723.5 KFM11725.1 - 3e-07 30.2 50.4 3.4 7.7 0.1 10.5 6 2 4 10 10 10 2 Zinc ribbon domain zf-C2HC_2 PF13913.1 KFM11725.1 - 3.3e-06 26.5 4.6 3.5e-05 23.3 0.8 8.0 9 0 0 9 9 8 2 zinc-finger of a C2HC-type zf-Di19 PF05605.7 KFM11725.1 - 0.00016 21.6 41.7 0.002 18.2 1.6 6.5 3 2 5 8 8 8 5 Drought induced 19 protein (Di19), zinc-binding RRN7 PF11781.3 KFM11725.1 - 0.0013 18.2 30.8 6 6.4 0.2 10.4 11 0 0 11 11 11 1 RNA polymerase I-specific transcription initiation factor Rrn7 BolA PF01722.13 KFM11725.1 - 0.0024 17.7 6.7 12 5.9 0.0 5.2 5 1 1 6 6 6 0 BolA-like protein XPA_N PF01286.13 KFM11725.1 - 0.005 16.4 34.2 3.3 7.4 0.0 10.4 11 0 0 11 11 11 1 XPA protein N-terminal MBD PF01429.14 KFM11725.1 - 0.043 13.3 2.5 18 4.9 0.4 4.7 2 1 0 2 2 2 0 Methyl-CpG binding domain DNA_RNApol_7kD PF03604.8 KFM11725.1 - 0.053 13.0 44.6 11 5.5 0.2 10.5 11 0 0 11 11 11 0 DNA directed RNA polymerase, 7 kDa subunit DrsE PF02635.10 KFM11725.1 - 0.074 13.1 0.2 35 4.4 0.0 3.6 2 2 2 4 4 4 0 DsrE/DsrF-like family Mut7-C PF01927.11 KFM11725.1 - 0.085 12.8 29.2 0.042 13.8 1.0 6.0 1 1 4 5 5 5 0 Mut7-C RNAse domain Tmemb_55A PF09788.4 KFM11725.1 - 0.11 11.5 14.8 0.066 12.3 0.3 4.1 2 2 0 2 2 2 0 Transmembrane protein 55A zf-ISL3 PF14690.1 KFM11725.1 - 0.36 10.8 0.2 0.36 10.8 0.1 9.8 11 0 0 11 11 11 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Yippee-Mis18 PF03226.9 KFM11725.1 - 0.98 9.4 22.0 0.34 10.9 0.8 5.1 3 1 2 5 5 5 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly GAGA PF09237.6 KFM11725.1 - 7.5 6.2 18.7 18 4.9 0.0 5.7 2 1 3 6 6 6 0 GAGA factor Evr1_Alr PF04777.8 KFM11725.1 - 7.6 6.5 37.7 8.9 6.2 0.2 8.9 1 1 9 10 10 10 0 Erv1 / Alr family DUF3421 PF11901.3 KFM11726.1 - 4.4e-16 58.6 0.1 6.2e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3421) Snf7 PF03357.16 KFM11727.1 - 4.1e-37 127.1 30.1 4.7e-37 127.0 20.9 1.0 1 0 0 1 1 1 1 Snf7 YlqD PF11068.3 KFM11727.1 - 0.67 9.9 17.3 0.18 11.8 4.1 2.1 1 1 1 2 2 2 0 YlqD protein DUF4140 PF13600.1 KFM11727.1 - 2.1 8.8 5.8 4.6 7.7 1.3 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Pox_A_type_inc PF04508.7 KFM11727.1 - 2.2 8.2 5.8 17 5.5 1.7 3.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Snapin_Pallidin PF14712.1 KFM11727.1 - 2.6 8.4 15.3 1.8 8.9 0.7 3.1 1 1 2 3 3 3 0 Snapin/Pallidin zf-B_box PF00643.19 KFM11728.1 - 1.3e-09 37.7 7.9 1.6e-09 37.4 5.5 1.1 1 0 0 1 1 1 1 B-box zinc finger zf-UBR PF02207.15 KFM11728.1 - 0.0066 16.1 3.6 0.01 15.5 2.5 1.4 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) HemX PF04375.9 KFM11728.1 - 0.044 12.3 0.2 0.045 12.3 0.2 1.0 1 0 0 1 1 1 0 HemX M157 PF11624.3 KFM11728.1 - 0.063 12.3 0.2 0.069 12.2 0.1 1.0 1 0 0 1 1 1 0 MHC class I-like protein M157 FYVE_2 PF02318.11 KFM11728.1 - 0.071 13.0 1.2 0.079 12.8 0.8 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger IBR PF01485.16 KFM11728.1 - 0.083 12.7 4.3 0.17 11.7 3.0 1.6 1 1 0 1 1 1 0 IBR domain KLRAQ PF10205.4 KFM11728.1 - 0.11 12.5 1.1 0.28 11.2 0.7 1.6 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein AMP-binding PF00501.23 KFM11729.1 - 7.6e-43 146.4 0.0 4.6e-27 94.4 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 KFM11729.1 - 3.8e-10 40.5 0.0 7.5e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Yae1_N PF09811.4 KFM11729.1 - 0.00017 21.0 15.7 0.007 15.8 10.9 2.6 1 1 0 1 1 1 1 Essential protein Yae1, N terminal Glyco_transf_54 PF04666.8 KFM11730.1 - 2.9e-108 361.1 1.2 3.9e-108 360.7 0.8 1.1 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Glyco_transf_25 PF01755.12 KFM11730.1 - 0.0057 16.3 0.1 0.013 15.1 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Pro-NT_NN PF07421.6 KFM11731.1 - 3.5e-62 208.8 0.5 3.9e-62 208.7 0.4 1.0 1 0 0 1 1 1 1 Neurotensin/neuromedin N precursor RA PF00788.18 KFM11732.1 - 8.3e-08 32.6 0.5 4.4e-06 27.1 0.0 2.8 2 1 0 2 2 2 1 Ras association (RalGDS/AF-6) domain DUF3087 PF11286.3 KFM11732.1 - 0.25 10.5 2.3 0.59 9.3 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) Ly49 PF08391.5 KFM11732.1 - 2.6 8.1 8.1 2.3 8.3 0.5 2.6 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region Phospholip_A2_2 PF05826.7 KFM11733.1 - 2.8e-05 23.9 0.0 4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Phospholipase A2 zf-CW PF07496.10 KFM11734.1 - 1.6e-16 59.6 4.4 3.8e-16 58.5 3.1 1.7 1 0 0 1 1 1 1 CW-type Zinc Finger HATPase_c_3 PF13589.1 KFM11734.1 - 9.7e-09 35.0 0.0 3.5e-08 33.1 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RRM_1 PF00076.17 KFM11737.1 - 1.3e-51 172.0 0.0 1.2e-17 63.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM11737.1 - 2.9e-38 129.6 0.0 2.7e-12 46.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM11737.1 - 2.1e-29 101.0 1.8 1.3e-09 37.7 0.1 3.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 KFM11737.1 - 4.4e-07 29.7 0.0 0.31 11.0 0.0 3.6 3 0 0 3 3 3 3 RNA binding domain RRM_3 PF08777.6 KFM11737.1 - 0.022 14.5 0.0 3.7 7.4 0.0 3.3 3 0 0 3 3 3 0 RNA binding motif Limkain-b1 PF11608.3 KFM11737.1 - 0.054 13.2 0.1 2.9 7.7 0.0 3.0 3 0 0 3 3 3 0 Limkain b1 ECH PF00378.15 KFM11739.1 - 6.1e-52 176.1 0.1 7.1e-52 175.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 KFM11739.1 - 0.085 12.6 0.1 1.2 8.9 0.0 2.3 1 1 1 2 2 2 0 Peptidase family S49 SARG PF15385.1 KFM11740.1 - 4.8e-84 283.5 30.4 1.6e-83 281.7 21.1 1.9 1 1 0 1 1 1 1 Specifically androgen-regulated gene protein MIF4G PF02854.14 KFM11741.1 - 2.3e-78 262.3 10.9 6.4e-41 140.0 0.0 3.7 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.9 KFM11741.1 - 5.8e-46 156.3 19.6 5.8e-46 156.3 13.6 5.7 4 2 1 5 5 5 1 Up-frameshift suppressor 2 Transket_pyr PF02779.19 KFM11742.1 - 1.4e-62 210.3 0.0 2.3e-62 209.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 KFM11742.1 - 9.9e-44 149.2 0.0 2.1e-43 148.1 0.0 1.5 1 1 0 1 1 1 1 Dehydrogenase E1 component SecY PF00344.15 KFM11743.1 - 2.5e-96 322.6 14.4 3.4e-96 322.1 10.0 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 KFM11743.1 - 1.4e-19 69.2 0.3 4.3e-19 67.7 0.2 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p D123 PF07065.9 KFM11744.1 - 4e-100 334.7 0.0 4.9e-100 334.4 0.0 1.0 1 0 0 1 1 1 1 D123 DUF4343 PF14243.1 KFM11744.1 - 4.1e-05 23.4 0.0 6.5e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4343) DUF466 PF04328.8 KFM11744.1 - 0.071 12.9 0.3 0.14 12.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF466) ATPgrasp_YheCD PF14398.1 KFM11744.1 - 0.082 11.6 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 YheC/D like ATP-grasp RVT_1 PF00078.22 KFM11745.1 - 0.035 13.4 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.20 KFM11746.1 - 4.9e-76 255.3 0.0 5.8e-76 255.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM11746.1 - 6.1e-35 120.5 0.0 7.6e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM11746.1 - 6.9e-08 31.7 0.0 8.7e-08 31.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KFM11746.1 - 0.00038 19.8 1.3 0.00038 19.8 0.0 1.6 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 KFM11746.1 - 0.00055 19.0 0.0 0.00094 18.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFM11746.1 - 0.002 17.8 0.0 0.26 10.9 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KFM11746.1 - 0.0079 15.5 0.1 0.026 13.8 0.0 1.8 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 KFM11746.1 - 0.059 12.1 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase YscO PF07321.7 KFM11747.1 - 1e-06 28.6 9.5 1.4e-06 28.2 6.6 1.2 1 0 0 1 1 1 1 Type III secretion protein YscO Myosin_tail_1 PF01576.14 KFM11747.1 - 0.00011 20.0 5.5 0.00013 19.8 3.8 1.0 1 0 0 1 1 1 1 Myosin tail Fib_alpha PF08702.5 KFM11747.1 - 0.00062 19.9 2.1 0.0011 19.0 1.4 1.4 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family bZIP_1 PF00170.16 KFM11747.1 - 0.00085 19.2 3.4 0.00085 19.2 2.4 1.9 1 1 0 1 1 1 1 bZIP transcription factor Laminin_I PF06008.9 KFM11747.1 - 0.00097 18.5 5.0 0.0012 18.2 3.4 1.0 1 0 0 1 1 1 1 Laminin Domain I KLRAQ PF10205.4 KFM11747.1 - 0.0013 18.6 7.7 0.0017 18.3 5.4 1.3 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein IncA PF04156.9 KFM11747.1 - 0.0015 18.2 4.6 0.0018 17.8 3.2 1.1 1 0 0 1 1 1 1 IncA protein FlaC_arch PF05377.6 KFM11747.1 - 0.002 17.9 0.9 0.0041 16.9 0.6 1.5 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) Tropomyosin_1 PF12718.2 KFM11747.1 - 0.002 17.9 8.8 0.0027 17.5 6.1 1.1 1 0 0 1 1 1 1 Tropomyosin like BLOC1_2 PF10046.4 KFM11747.1 - 0.0022 18.0 1.7 0.0038 17.3 1.2 1.4 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Herpes_UL6 PF01763.11 KFM11747.1 - 0.0032 15.7 3.2 0.0034 15.6 2.2 1.1 1 0 0 1 1 1 1 Herpesvirus UL6 like FH2 PF02181.18 KFM11747.1 - 0.0033 16.3 1.9 0.0039 16.1 1.3 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain RRF_GI PF12614.3 KFM11747.1 - 0.0035 17.1 1.3 0.0051 16.6 0.9 1.4 1 0 0 1 1 1 1 Ribosome recycling factor Atg14 PF10186.4 KFM11747.1 - 0.0042 16.0 6.4 0.0047 15.9 4.4 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Mnd1 PF03962.10 KFM11747.1 - 0.0043 16.7 2.8 0.0043 16.7 2.0 1.1 1 0 0 1 1 1 1 Mnd1 family Cluap1 PF10234.4 KFM11747.1 - 0.0055 15.9 5.7 0.0062 15.7 4.0 1.1 1 0 0 1 1 1 1 Clusterin-associated protein-1 AAA_13 PF13166.1 KFM11747.1 - 0.0072 14.8 2.6 0.0097 14.4 1.8 1.1 1 0 0 1 1 1 1 AAA domain DUF1664 PF07889.7 KFM11747.1 - 0.0075 16.0 3.2 0.0098 15.6 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Laminin_II PF06009.7 KFM11747.1 - 0.0087 15.8 3.9 0.012 15.3 2.7 1.1 1 0 0 1 1 1 1 Laminin Domain II DUF489 PF04356.7 KFM11747.1 - 0.0089 15.6 1.7 0.011 15.3 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF489) Striatin PF08232.7 KFM11747.1 - 0.012 15.9 4.5 0.015 15.5 3.1 1.3 1 0 0 1 1 1 0 Striatin family Spc7 PF08317.6 KFM11747.1 - 0.012 14.2 5.1 0.013 14.1 3.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Bacillus_HBL PF05791.6 KFM11747.1 - 0.013 14.9 1.3 0.017 14.5 0.9 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF2067 PF09840.4 KFM11747.1 - 0.013 15.0 1.1 0.017 14.6 0.7 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2067) Rabaptin PF03528.10 KFM11747.1 - 0.02 14.7 4.5 0.027 14.3 3.1 1.3 1 0 0 1 1 1 0 Rabaptin EzrA PF06160.7 KFM11747.1 - 0.021 13.0 3.9 0.026 12.7 2.7 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Snapin_Pallidin PF14712.1 KFM11747.1 - 0.023 15.0 3.5 0.037 14.3 2.5 1.4 1 0 0 1 1 1 0 Snapin/Pallidin TMF_DNA_bd PF12329.3 KFM11747.1 - 0.023 14.4 9.9 0.032 14.0 6.9 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF972 PF06156.8 KFM11747.1 - 0.024 14.9 4.8 0.037 14.3 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Rootletin PF15035.1 KFM11747.1 - 0.025 14.5 7.9 0.03 14.3 5.5 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion P4Ha_N PF08336.6 KFM11747.1 - 0.03 14.1 3.5 0.048 13.4 2.4 1.4 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF3450 PF11932.3 KFM11747.1 - 0.031 13.5 2.7 0.031 13.5 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) EMP24_GP25L PF01105.19 KFM11747.1 - 0.034 13.8 4.6 0.043 13.5 3.2 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Prominin PF05478.6 KFM11747.1 - 0.036 11.6 2.2 0.044 11.3 1.5 1.1 1 0 0 1 1 1 0 Prominin PRKCSH-like PF12999.2 KFM11747.1 - 0.037 13.6 1.4 0.044 13.3 1.0 1.1 1 0 0 1 1 1 0 Glucosidase II beta subunit-like SpoVIF PF14069.1 KFM11747.1 - 0.039 13.6 2.9 0.083 12.6 2.0 1.6 1 1 0 1 1 1 0 Stage VI sporulation protein F DivIC PF04977.10 KFM11747.1 - 0.05 13.0 7.7 0.083 12.3 5.2 1.5 1 1 0 1 1 1 0 Septum formation initiator HemX PF04375.9 KFM11747.1 - 0.052 12.1 3.4 0.061 11.9 2.3 1.2 1 0 0 1 1 1 0 HemX APG6 PF04111.7 KFM11747.1 - 0.052 12.5 4.7 0.059 12.3 3.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 ADIP PF11559.3 KFM11747.1 - 0.055 13.3 10.4 0.077 12.8 7.2 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Cauli_AT PF03233.8 KFM11747.1 - 0.058 13.1 2.4 0.076 12.7 1.7 1.4 1 0 0 1 1 1 0 Aphid transmission protein NPV_P10 PF05531.7 KFM11747.1 - 0.062 13.5 2.3 2.3 8.5 0.1 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2968 PF11180.3 KFM11747.1 - 0.062 12.6 4.7 0.086 12.2 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF904 PF06005.7 KFM11747.1 - 0.067 13.4 9.3 0.1 12.9 6.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) V_ATPase_I PF01496.14 KFM11747.1 - 0.076 10.8 5.1 0.089 10.6 3.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ax_dynein_light PF10211.4 KFM11747.1 - 0.098 12.4 9.2 0.13 12.1 6.4 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain DegS PF05384.6 KFM11747.1 - 0.1 11.8 7.1 0.18 11.0 4.9 1.4 1 1 0 1 1 1 0 Sensor protein DegS DUF3552 PF12072.3 KFM11747.1 - 0.1 11.7 8.2 0.13 11.4 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Med4 PF10018.4 KFM11747.1 - 0.13 11.6 4.9 0.18 11.1 3.4 1.2 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 SlyX PF04102.7 KFM11747.1 - 0.13 12.6 5.5 0.36 11.2 3.8 1.8 1 1 0 1 1 1 0 SlyX TMPIT PF07851.8 KFM11747.1 - 0.14 11.1 4.0 0.19 10.7 2.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein Fzo_mitofusin PF04799.8 KFM11747.1 - 0.16 11.3 3.4 0.2 11.0 2.3 1.4 1 0 0 1 1 1 0 fzo-like conserved region Rab5-bind PF09311.6 KFM11747.1 - 0.16 11.8 10.3 0.2 11.5 7.1 1.1 1 0 0 1 1 1 0 Rabaptin-like protein GrpE PF01025.14 KFM11747.1 - 0.18 11.3 6.0 0.25 10.8 4.2 1.2 1 0 0 1 1 1 0 GrpE Prefoldin_2 PF01920.15 KFM11747.1 - 0.2 11.4 7.8 0.14 11.9 4.2 1.5 1 1 0 1 1 1 0 Prefoldin subunit DUF2951 PF11166.3 KFM11747.1 - 0.26 11.1 7.7 1.1 9.1 4.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) DUF342 PF03961.8 KFM11747.1 - 0.29 9.5 3.2 0.32 9.3 2.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Nnf1 PF03980.9 KFM11747.1 - 0.29 11.1 5.5 0.27 11.2 0.8 2.1 1 1 1 2 2 2 0 Nnf1 UPF0242 PF06785.6 KFM11747.1 - 0.31 9.6 5.3 0.38 9.3 3.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) COG2 PF06148.6 KFM11747.1 - 0.4 10.5 5.8 0.63 9.9 4.0 1.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3251 PF11622.3 KFM11747.1 - 0.43 9.9 3.2 0.67 9.3 2.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3251) DUF3373 PF11853.3 KFM11747.1 - 0.7 8.3 3.1 0.85 8.0 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Seryl_tRNA_N PF02403.17 KFM11747.1 - 0.77 9.8 8.7 1.1 9.2 6.0 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Viral_P18 PF04521.8 KFM11747.1 - 1.1 8.7 6.2 1.6 8.1 4.3 1.3 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein Cep57_CLD_2 PF14197.1 KFM11747.1 - 1.2 9.0 9.9 2.2 8.2 6.9 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 DUF2681 PF10883.3 KFM11747.1 - 1.2 9.3 9.2 1.9 8.7 6.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) XhlA PF10779.4 KFM11747.1 - 1.8 8.5 5.7 3.1 7.7 3.9 1.5 1 1 0 1 1 1 0 Haemolysin XhlA Synaptobrevin PF00957.16 KFM11747.1 - 1.9 8.1 5.2 3.5 7.3 3.6 1.5 1 1 0 1 1 1 0 Synaptobrevin DUF4446 PF14584.1 KFM11747.1 - 2 8.2 6.3 4.3 7.1 4.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) FUSC-like PF12805.2 KFM11747.1 - 2.4 6.9 5.5 3.5 6.4 3.8 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS DUF724 PF05266.9 KFM11747.1 - 2.5 7.7 10.1 2.4 7.7 6.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF724) NEMO PF11577.3 KFM11748.1 - 3.1e-29 100.5 13.0 3.1e-29 100.5 9.0 5.8 6 0 0 6 6 6 2 NF-kappa-B essential modulator NEMO HALZ PF02183.13 KFM11748.1 - 0.029 14.0 1.1 0.029 14.0 0.8 7.2 8 0 0 8 8 8 0 Homeobox associated leucine zipper IL17 PF06083.6 KFM11748.1 - 0.15 12.0 1.3 0.59 10.2 0.1 2.6 2 1 0 2 2 2 0 Interleukin-17 Phi_1 PF04674.7 KFM11748.1 - 0.23 10.5 0.7 0.43 9.7 0.1 1.6 1 1 1 2 2 2 0 Phosphate-induced protein 1 conserved region Mcm10 PF09332.6 KFM11749.1 - 1.3e-131 439.0 10.3 1.3e-131 439.0 7.1 2.5 2 1 0 2 2 2 1 Mcm10 replication factor zf-primase PF09329.6 KFM11749.1 - 1.2e-17 63.1 2.1 3.6e-17 61.6 1.5 1.9 1 0 0 1 1 1 1 Primase zinc finger DUF3138 PF11336.3 KFM11749.1 - 0.64 8.1 3.7 0.28 9.3 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) PhyH PF05721.8 KFM11750.1 - 3.7e-41 141.5 0.0 4.6e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AIRS_C PF02769.17 KFM11751.1 - 1e-27 97.0 0.1 1.5e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.19 KFM11751.1 - 2.7e-11 43.5 0.1 6.6e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain BEN PF10523.4 KFM11752.1 - 2.1e-12 46.8 0.1 5.7e-12 45.5 0.1 1.7 1 0 0 1 1 1 1 BEN domain Prp18 PF02840.10 KFM11753.1 - 1e-58 197.3 0.1 1.9e-58 196.3 0.1 1.5 1 0 0 1 1 1 1 Prp18 domain PRP4 PF08799.6 KFM11753.1 - 1.2e-13 50.0 3.9 1.2e-13 50.0 2.7 2.2 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like Phage_int_SAM_4 PF13495.1 KFM11753.1 - 0.071 13.4 0.1 5.3 7.4 0.0 2.6 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain DUF3338 PF11819.3 KFM11754.1 - 1.4e-60 202.6 5.0 1.4e-60 202.6 3.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3338) FERM_M PF00373.13 KFM11754.1 - 5.6e-20 71.7 0.0 5.6e-20 71.7 0.0 3.1 2 1 0 2 2 2 1 FERM central domain FERM_N PF09379.5 KFM11754.1 - 1e-12 47.9 0.3 4e-12 46.0 0.1 2.1 2 0 0 2 2 2 1 FERM N-terminal domain FERM_C PF09380.5 KFM11754.1 - 3.2e-06 27.2 0.2 1.1e-05 25.5 0.1 2.0 1 1 0 1 1 1 1 FERM C-terminal PH-like domain DUF1151 PF06625.6 KFM11755.1 - 5.5e-52 174.6 21.2 6.3e-52 174.4 14.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1151) MRP-S26 PF14943.1 KFM11755.1 - 0.068 12.7 14.1 0.078 12.5 9.8 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 DUF4045 PF13254.1 KFM11755.1 - 3.8 6.6 12.1 2.1 7.5 0.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4045) Peptidase_A17 PF05380.8 KFM11756.1 - 0.12 12.2 0.3 0.5 10.2 0.1 2.0 2 0 0 2 2 2 0 Pao retrotransposon peptidase HSP70 PF00012.15 KFM11757.1 - 2.3e-95 319.7 0.0 2.6e-95 319.5 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFM11757.1 - 3.7e-11 42.2 0.0 6.1e-11 41.4 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein B5 PF03484.10 KFM11757.1 - 0.0051 16.6 0.1 0.19 11.5 0.0 2.6 2 1 0 2 2 2 1 tRNA synthetase B5 domain SET PF00856.23 KFM11758.1 - 2.7e-27 96.0 0.1 9.9e-27 94.2 0.1 1.9 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.11 KFM11758.1 - 2.6e-22 79.0 2.9 2.6e-22 79.0 2.0 2.3 2 0 0 2 2 2 1 Pre-SET motif Chromo PF00385.19 KFM11758.1 - 2.1e-14 52.9 1.8 4.3e-14 51.9 1.3 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain IGPS PF00218.16 KFM11758.1 - 0.11 11.4 0.0 0.28 10.2 0.0 1.6 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase DRMBL PF07522.9 KFM11759.1 - 5.4e-18 65.0 0.1 1.2e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 KFM11759.1 - 2.4e-05 23.9 0.0 5.6e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KFM11759.1 - 0.011 15.3 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Meiosis_expr PF15163.1 KFM11760.1 - 1.3e-36 124.7 8.0 1.5e-36 124.5 5.6 1.0 1 0 0 1 1 1 1 Meiosis-expressed DUF2678 PF10856.3 KFM11761.1 - 1.7e-47 159.9 6.1 1.8e-47 159.8 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2678) Polysacc_synt_C PF14667.1 KFM11761.1 - 4.2e-05 23.3 1.9 5.3e-05 23.0 1.3 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis C-terminal domain ABC2_membrane_3 PF12698.2 KFM11761.1 - 0.11 11.5 4.5 0.13 11.2 3.1 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein Peptidase_M50 PF02163.17 KFM11761.1 - 0.13 11.1 3.2 3.2 6.6 2.1 2.0 1 1 0 1 1 1 0 Peptidase family M50 7TMR-DISM_7TM PF07695.6 KFM11761.1 - 1.5 8.4 12.6 11 5.6 8.9 1.8 1 1 0 1 1 1 0 7TM diverse intracellular signalling DUF2417 PF10329.4 KFM11761.1 - 2.8 7.3 6.5 3.9 6.8 4.5 1.3 1 1 0 1 1 1 0 Region of unknown function (DUF2417) YesK PF14150.1 KFM11761.1 - 3.9 7.6 9.8 0.21 11.6 1.7 2.0 1 1 1 2 2 2 0 YesK-like protein DUF4131 PF13567.1 KFM11761.1 - 6.6 6.0 8.8 0.59 9.5 1.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Myb_DNA-binding PF00249.26 KFM11762.1 - 2.3e-22 78.7 9.4 6.4e-14 51.7 0.3 4.1 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFM11762.1 - 9.5e-21 73.6 8.8 1.7e-13 50.4 0.1 4.7 4 1 1 5 5 5 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 KFM11762.1 - 0.032 14.3 0.5 0.032 14.3 0.3 3.6 3 1 1 4 4 4 0 Myb/SANT-like DNA-binding domain GCC2_GCC3 PF07699.8 KFM11763.1 - 4.4e-12 45.3 74.9 1e-05 24.9 4.9 8.8 5 3 4 9 9 9 7 GCC2 and GCC3 ANF_receptor PF01094.23 KFM11764.1 - 1.3e-93 313.5 0.2 1.7e-93 313.1 0.1 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.17 KFM11764.1 - 2.7e-79 265.8 23.0 4.5e-79 265.1 15.9 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.9 KFM11764.1 - 1.7e-15 56.4 10.8 4.3e-15 55.1 7.5 1.7 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.1 KFM11764.1 - 3.8e-09 36.3 0.1 7.6e-09 35.3 0.0 1.6 2 1 0 2 2 2 1 Periplasmic binding protein Sema PF01403.14 KFM11765.1 - 2.2e-170 566.8 0.0 1e-169 564.7 0.0 1.8 1 1 1 2 2 2 2 Sema domain V-set PF07686.12 KFM11765.1 - 5.5e-05 23.0 0.0 0.00017 21.4 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin V-set domain PSI PF01437.20 KFM11765.1 - 0.00016 21.7 9.6 0.00037 20.5 6.7 1.6 1 0 0 1 1 1 1 Plexin repeat I-set PF07679.11 KFM11765.1 - 0.00083 19.1 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM11765.1 - 0.0034 17.4 0.1 0.02 15.0 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain WD40 PF00400.27 KFM11765.1 - 0.047 13.6 0.0 0.15 11.9 0.0 1.9 1 0 0 1 1 1 0 WD domain, G-beta repeat Sema PF01403.14 KFM11766.1 - 1.8e-176 586.9 0.0 4.4e-176 585.6 0.0 1.6 2 0 0 2 2 2 1 Sema domain V-set PF07686.12 KFM11766.1 - 3.6e-06 26.8 0.1 1.1e-05 25.2 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 KFM11766.1 - 0.00013 22.0 0.0 0.0004 20.4 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin domain PSI PF01437.20 KFM11766.1 - 0.00017 21.6 7.3 0.00017 21.6 5.0 2.1 2 0 0 2 2 2 1 Plexin repeat Ig_2 PF13895.1 KFM11766.1 - 0.0014 18.6 0.0 0.0043 17.1 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 KFM11766.1 - 0.014 15.2 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin I-set domain Ig_3 PF13927.1 KFM11766.1 - 0.045 14.2 0.0 0.58 10.7 0.0 2.6 2 0 0 2 2 2 0 Immunoglobulin domain Sema PF01403.14 KFM11767.1 - 9.2e-169 561.5 0.0 1.3e-168 561.0 0.0 1.2 1 0 0 1 1 1 1 Sema domain PSI PF01437.20 KFM11767.1 - 0.00046 20.2 7.2 0.00046 20.2 5.0 1.9 2 0 0 2 2 2 1 Plexin repeat V-set PF07686.12 KFM11767.1 - 0.0023 17.8 0.0 0.0079 16.0 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 KFM11767.1 - 0.0088 16.1 0.0 0.041 14.0 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain C2 PF00168.25 KFM11768.1 - 5.6e-34 115.8 0.0 6.9e-23 80.3 0.0 3.0 2 0 0 2 2 2 2 C2 domain PDZ PF00595.19 KFM11768.1 - 5.3e-07 29.7 0.3 1.5e-06 28.2 0.2 1.7 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) VGCC_alpha2 PF08473.6 KFM11771.1 - 2e-48 162.0 0.6 4.2e-48 161.0 0.5 1.6 1 0 0 1 1 1 1 Neuronal voltage-dependent calcium channel alpha 2acd VWA_N PF08399.6 KFM11771.1 - 2.7e-37 128.1 0.4 1.2e-36 126.0 0.1 2.3 2 0 0 2 2 2 1 VWA N-terminal Cache_1 PF02743.13 KFM11771.1 - 9.9e-28 95.5 0.2 5.8e-27 93.0 0.0 2.3 2 0 0 2 2 2 1 Cache domain VWA PF00092.23 KFM11771.1 - 3.9e-13 49.5 0.6 7.6e-13 48.5 0.4 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 KFM11771.1 - 2.6e-10 40.1 0.0 4.3e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 KFM11771.1 - 3e-07 30.7 0.0 6.3e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Cache_2 PF08269.6 KFM11771.1 - 0.043 13.7 0.0 0.14 12.1 0.0 1.9 1 0 0 1 1 1 0 Cache domain Kringle PF00051.13 KFM11772.1 - 4.1e-110 360.0 41.5 2e-29 101.4 4.7 4.5 4 0 0 4 4 4 4 Kringle domain Trypsin PF00089.21 KFM11772.1 - 5.4e-45 153.6 0.1 9.8e-45 152.8 0.0 1.4 1 0 0 1 1 1 1 Trypsin PAN_1 PF00024.21 KFM11772.1 - 1.5e-10 40.7 0.9 4.6e-10 39.1 0.6 1.9 1 0 0 1 1 1 1 PAN domain DUF1986 PF09342.6 KFM11772.1 - 0.0016 17.7 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) DUF1495 PF07381.6 KFM11772.1 - 0.14 11.8 0.0 12 5.6 0.0 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain (DUF1495) Sema PF01403.14 KFM11774.1 - 3.5e-168 559.6 0.0 4.8e-168 559.1 0.0 1.2 1 0 0 1 1 1 1 Sema domain I-set PF07679.11 KFM11774.1 - 5.5e-06 26.1 0.2 1.6e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin I-set domain PSI PF01437.20 KFM11774.1 - 0.00035 20.6 8.4 0.00035 20.6 5.8 2.4 2 0 0 2 2 2 1 Plexin repeat V-set PF07686.12 KFM11774.1 - 0.00045 20.0 0.3 0.0023 17.8 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin V-set domain Ig_2 PF13895.1 KFM11774.1 - 0.0016 18.5 0.0 0.0045 17.0 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFM11774.1 - 0.01 16.3 0.0 0.039 14.4 0.0 2.0 1 0 0 1 1 1 0 Immunoglobulin domain CD36 PF01130.16 KFM11775.1 - 2.3e-141 471.2 0.0 2.7e-141 471.0 0.0 1.0 1 0 0 1 1 1 1 CD36 family DUF3068 PF11271.3 KFM11775.1 - 0.15 11.0 0.0 0.34 9.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3068) G-alpha PF00503.15 KFM11776.1 - 1.6e-123 412.2 1.4 1.9e-123 412.0 0.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KFM11776.1 - 1.7e-15 56.6 1.2 2.1e-11 43.3 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFM11776.1 - 0.0093 15.1 3.2 0.81 8.7 0.3 2.5 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 KFM11776.1 - 0.045 13.2 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2951 PF11166.3 KFM11776.1 - 0.076 12.8 0.1 0.23 11.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) Ras PF00071.17 KFM11776.1 - 0.15 11.4 1.1 10 5.4 0.2 2.5 2 1 0 2 2 2 0 Ras family G-alpha PF00503.15 KFM11777.1 - 4.1e-135 450.4 2.7 4.9e-135 450.1 1.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KFM11777.1 - 1.6e-17 63.3 0.8 4.8e-10 38.9 0.1 3.4 2 1 1 3 3 3 3 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFM11777.1 - 0.00032 19.9 2.3 0.06 12.4 0.5 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 KFM11777.1 - 0.0004 20.8 0.5 1.6 9.2 0.0 2.8 3 0 0 3 3 3 2 Miro-like protein AAA_29 PF13555.1 KFM11777.1 - 0.042 13.3 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Telomere_Sde2 PF13019.1 KFM11778.1 - 6.7e-23 81.1 3.4 9e-23 80.7 2.4 1.2 1 0 0 1 1 1 1 Telomere stability and silencing PVL_ORF50 PF07768.6 KFM11778.1 - 0.016 15.2 4.3 0.026 14.5 3.0 1.3 1 0 0 1 1 1 0 PVL ORF-50-like family PcfJ PF14284.1 KFM11778.1 - 0.075 12.5 1.1 0.091 12.2 0.8 1.2 1 0 0 1 1 1 0 PcfJ-like protein FadA PF09403.5 KFM11778.1 - 0.16 12.0 1.8 0.23 11.4 1.3 1.3 1 0 0 1 1 1 0 Adhesion protein FadA Exonuc_VII_L PF02601.10 KFM11778.1 - 0.19 10.8 1.2 0.23 10.6 0.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Pox_A_type_inc PF04508.7 KFM11778.1 - 2 8.3 5.7 3.9 7.4 2.6 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat GOLD_2 PF13897.1 KFM11779.1 - 6.5e-70 233.6 4.1 6.5e-70 233.6 2.9 3.0 2 1 0 2 2 2 1 Golgi-dynamics membrane-trafficking ACBP PF00887.14 KFM11779.1 - 3.1e-16 58.7 0.0 1.1e-15 57.0 0.0 1.9 1 0 0 1 1 1 1 Acyl CoA binding protein PAT1 PF09770.4 KFM11779.1 - 0.57 8.3 24.6 0.99 7.5 17.1 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Merozoite_SPAM PF07133.6 KFM11779.1 - 1.2 9.0 28.9 0.92 9.3 11.5 2.4 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) U79_P34 PF03064.11 KFM11779.1 - 1.2 8.5 17.7 0.23 10.9 8.4 2.2 2 0 0 2 2 2 0 HSV U79 / HCMV P34 Ycf1 PF05758.7 KFM11779.1 - 3.5 5.2 21.1 1.3 6.6 12.6 1.6 2 0 0 2 2 2 0 Ycf1 MAP7 PF05672.6 KFM11779.1 - 4.9 6.5 59.9 0.19 11.0 35.5 2.3 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family DUF1675 PF07897.6 KFM11779.1 - 7.4 6.3 32.4 0.022 14.6 7.5 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1675) TLP-20 PF06088.6 KFM11779.1 - 8.4 6.0 8.9 6 6.5 0.3 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF1510 PF07423.6 KFM11779.1 - 9.7 5.4 23.1 2.6 7.3 8.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DIRP PF06584.8 KFM11780.1 - 5.6e-42 142.0 0.1 1.5e-41 140.6 0.1 1.8 1 0 0 1 1 1 1 DIRP FTA4 PF13093.1 KFM11780.1 - 0.016 14.6 2.2 0.039 13.3 1.5 1.8 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 zf-PARP PF00645.13 KFM11781.1 - 6.6e-17 61.5 7.6 9.3e-11 41.8 0.1 2.1 2 0 0 2 2 2 2 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region IPK PF03770.11 KFM11782.1 - 2.4e-44 151.3 0.0 5.1e-44 150.2 0.0 1.5 1 1 0 1 1 1 1 Inositol polyphosphate kinase Retrotrans_gag PF03732.12 KFM11782.1 - 0.26 11.3 2.2 1.8 8.6 0.0 2.9 3 1 1 4 4 4 0 Retrotransposon gag protein Presenilin PF01080.12 KFM11783.1 - 1.7e-165 550.7 18.8 6.5e-119 397.3 8.7 2.1 1 1 1 2 2 2 2 Presenilin ABC1 PF03109.11 KFM11784.1 - 1e-33 115.8 0.0 2e-33 114.8 0.0 1.5 1 0 0 1 1 1 1 ABC1 family DUF2959 PF11172.3 KFM11784.1 - 0.011 15.5 0.1 0.056 13.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2959) Oxidored_q1_N PF00662.15 KFM11784.1 - 0.14 11.7 0.2 0.25 10.9 0.2 1.3 1 0 0 1 1 1 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus CNH PF00780.17 KFM11785.1 - 4.6e-71 239.4 0.1 8.7e-71 238.5 0.1 1.5 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.20 KFM11785.1 - 5.7e-55 186.2 0.0 1.7e-54 184.7 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM11785.1 - 7.7e-29 100.5 0.0 2.2e-28 99.0 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase DMPK_coil PF08826.5 KFM11785.1 - 1.7e-25 88.6 11.2 1.7e-25 88.6 7.8 9.2 8 3 1 10 10 10 2 DMPK coiled coil domain like C1_1 PF00130.17 KFM11785.1 - 3.5e-11 42.6 7.5 9.4e-11 41.2 5.2 1.8 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 KFM11785.1 - 3.5e-06 27.4 2.3 1.2e-05 25.7 1.6 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain PBD PF00786.23 KFM11785.1 - 0.013 15.8 0.3 0.07 13.5 0.2 2.3 1 0 0 1 1 1 0 P21-Rho-binding domain Reo_sigmaC PF04582.7 KFM11785.1 - 0.88 8.6 19.6 1.3 8.1 0.1 3.8 2 2 2 4 4 4 0 Reovirus sigma C capsid protein Ald_Xan_dh_C2 PF02738.13 KFM11786.1 - 9.1e-216 717.4 0.0 1.4e-215 716.8 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 KFM11786.1 - 4.5e-55 185.7 0.0 7.4e-55 184.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.17 KFM11786.1 - 6.5e-37 126.0 0.8 1.1e-36 125.2 0.5 1.4 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.12 KFM11786.1 - 2.6e-32 110.8 0.0 6.2e-32 109.6 0.0 1.7 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.15 KFM11786.1 - 6.4e-28 96.4 0.1 2e-27 94.8 0.1 1.9 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 KFM11786.1 - 6.2e-09 35.4 0.5 6.2e-09 35.4 0.3 2.8 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain Dynamin_N PF00350.18 KFM11787.1 - 2.8e-19 69.5 0.0 1.2e-18 67.4 0.0 2.0 1 1 0 1 1 1 1 Dynamin family EF-hand_4 PF12763.2 KFM11787.1 - 3e-19 68.6 0.2 1.6e-18 66.3 0.0 2.2 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand MMR_HSR1 PF01926.18 KFM11787.1 - 1.1e-09 38.2 0.0 4.8e-09 36.1 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KFM11787.1 - 0.00018 21.9 0.0 0.0097 16.3 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 KFM11787.1 - 0.00083 18.8 0.2 0.034 13.5 0.3 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain EF-hand_1 PF00036.27 KFM11787.1 - 0.00099 18.2 0.6 0.0033 16.6 0.1 2.2 2 0 0 2 2 1 1 EF hand FeoB_N PF02421.13 KFM11787.1 - 0.009 15.3 0.0 0.35 10.1 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.11 KFM11787.1 - 0.011 14.7 0.0 0.067 12.2 0.0 2.2 3 0 0 3 3 3 0 AIG1 family AAA_28 PF13521.1 KFM11787.1 - 0.012 15.5 0.0 0.091 12.7 0.0 2.5 3 0 0 3 3 3 0 AAA domain Gtr1_RagA PF04670.7 KFM11787.1 - 0.013 14.6 0.1 0.23 10.5 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region UPF0278 PF08745.6 KFM11787.1 - 0.022 14.0 0.2 0.046 12.9 0.0 1.5 2 0 0 2 2 2 0 UPF0278 family AAA_22 PF13401.1 KFM11787.1 - 0.03 14.4 0.0 0.13 12.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 KFM11787.1 - 0.036 13.4 0.0 6 6.2 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain EF-hand_7 PF13499.1 KFM11787.1 - 0.067 13.3 0.1 0.23 11.6 0.0 2.0 2 0 0 2 2 1 0 EF-hand domain pair MobB PF03205.9 KFM11787.1 - 0.084 12.5 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Spc7 PF08317.6 KFM11787.1 - 0.094 11.3 3.7 0.034 12.8 0.7 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein AAA_16 PF13191.1 KFM11787.1 - 0.12 12.3 0.2 5.5 6.9 0.0 3.1 2 1 0 3 3 3 0 AAA ATPase domain UPF0079 PF02367.12 KFM11787.1 - 0.13 11.8 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 EF-hand_8 PF13833.1 KFM11787.1 - 0.37 10.4 2.2 0.49 10.0 0.3 2.1 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.1 KFM11787.1 - 2.7 7.4 5.0 0.57 9.6 0.5 2.2 2 0 0 2 2 2 0 EF hand Peptidase_C2 PF00648.16 KFM11788.1 - 2.3e-92 309.2 0.2 2.6e-92 309.0 0.2 1.0 1 0 0 1 1 1 1 Calpain family cysteine protease Glycos_transf_2 PF00535.21 KFM11789.1 - 4.6e-22 78.4 0.0 7e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 KFM11789.1 - 1.9e-16 60.2 2.0 3.9e-16 59.1 1.4 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.1 KFM11789.1 - 2.2e-07 30.8 0.0 4.1e-07 30.0 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 KFM11789.1 - 1.4e-06 27.6 0.0 2.9e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFM11789.1 - 1.5e-05 24.2 0.0 0.00012 21.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Peptidase_C2 PF00648.16 KFM11790.1 - 1.4e-106 355.8 0.2 1.6e-106 355.6 0.1 1.0 1 0 0 1 1 1 1 Calpain family cysteine protease Peptidase_C47 PF05543.8 KFM11790.1 - 0.00012 21.4 0.9 0.00019 20.9 0.1 1.5 2 0 0 2 2 2 1 Staphopain peptidase C47 Acyltransferase PF01553.16 KFM11792.1 - 3.3e-21 75.1 0.0 5.9e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Lbh PF15317.1 KFM11793.1 - 1.2e-37 128.0 2.7 1.4e-37 127.8 1.9 1.0 1 0 0 1 1 1 1 Cardiac transcription factor regulator, Developmental protein BCD PF15461.1 KFM11794.1 - 0.12 11.7 0.0 0.12 11.7 0.0 1.0 1 0 0 1 1 1 0 Beta-carotene 15,15'-dioxygenase Yippee-Mis18 PF03226.9 KFM11795.1 - 7.1e-18 64.4 0.2 8e-18 64.2 0.1 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HNH_5 PF14279.1 KFM11795.1 - 0.0046 16.9 0.1 0.072 13.1 0.0 2.3 2 0 0 2 2 2 1 HNH endonuclease Endonuclease_7 PF02945.10 KFM11795.1 - 0.0068 16.0 0.7 0.034 13.8 0.3 2.0 1 1 1 2 2 2 1 Recombination endonuclease VII SelR PF01641.13 KFM11795.1 - 0.011 15.4 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 0 SelR domain RIG-I_C-RD PF11648.3 KFM11795.1 - 0.016 15.0 0.1 0.025 14.4 0.1 1.3 1 0 0 1 1 1 0 C-terminal domain of RIG-I HECT_2 PF09814.4 KFM11795.1 - 0.042 12.5 0.8 0.09 11.4 0.0 1.7 1 1 1 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Mut7-C PF01927.11 KFM11795.1 - 0.11 12.4 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Mut7-C RNAse domain Sgf11 PF08209.6 KFM11795.1 - 0.31 10.3 3.0 6 6.2 0.1 2.4 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Rpr2 PF04032.11 KFM11795.1 - 0.68 9.8 2.8 4.3 7.2 0.2 2.2 1 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Ank_2 PF12796.2 KFM11796.1 - 2.1e-09 37.6 0.0 1.5e-05 25.2 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFM11796.1 - 2.1e-09 37.2 0.2 3.4e-06 27.1 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 KFM11796.1 - 3.2e-09 36.1 1.8 1.1e-06 28.1 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KFM11796.1 - 1.7e-06 28.3 0.1 0.29 11.6 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM11796.1 - 1.9e-06 27.5 0.1 0.0026 17.8 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat SOCS_box PF07525.11 KFM11796.1 - 0.0053 16.5 0.8 0.016 15.0 0.6 1.8 1 0 0 1 1 1 1 SOCS box CAP_GLY PF01302.20 KFM11797.1 - 9.5e-74 243.0 5.5 2e-25 88.2 0.4 3.5 3 0 0 3 3 3 3 CAP-Gly domain Ank_2 PF12796.2 KFM11797.1 - 3.4e-11 43.3 0.2 3.5e-08 33.6 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFM11797.1 - 3.5e-11 42.3 0.9 3.8e-06 26.4 0.1 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 KFM11797.1 - 7.8e-06 25.6 1.6 0.015 15.5 0.1 3.8 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.1 KFM11797.1 - 1.4e-05 25.4 0.2 0.0011 19.4 0.0 3.2 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM11797.1 - 0.00022 21.3 2.4 0.86 9.9 0.1 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) TrkA_C PF02080.16 KFM11797.1 - 0.021 14.3 0.0 0.4 10.3 0.0 2.6 2 0 0 2 2 2 0 TrkA-C domain Retinal PF15449.1 KFM11798.1 - 0 1478.2 77.0 0 1478.1 53.4 1.0 1 0 0 1 1 1 1 Retinal protein CLASP_N PF12348.3 KFM11799.1 - 7.3e-18 64.7 4.2 7.3e-18 64.7 2.9 2.8 3 1 0 3 3 3 1 CLASP N terminal HEAT_2 PF13646.1 KFM11799.1 - 7.9e-06 26.0 8.4 0.0078 16.4 0.1 3.8 4 0 0 4 4 4 2 HEAT repeats DUF2435 PF10363.4 KFM11799.1 - 4e-05 23.4 3.3 2.7 7.9 0.1 4.5 2 2 2 4 4 4 2 Protein of unknown function (DUF2435) NUC173 PF08161.7 KFM11799.1 - 0.00078 18.8 2.3 0.48 9.7 0.2 2.6 2 0 0 2 2 2 2 NUC173 domain HEAT PF02985.17 KFM11799.1 - 0.0016 18.3 7.0 5.8 7.2 0.0 6.3 8 0 0 8 8 8 1 HEAT repeat DNA_alkylation PF08713.6 KFM11799.1 - 0.0099 15.4 1.1 0.78 9.2 0.0 3.0 2 1 1 3 3 3 1 DNA alkylation repair enzyme Vac14_Fab1_bd PF12755.2 KFM11799.1 - 0.021 15.2 2.9 6.9 7.1 0.1 3.7 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region MFS_3 PF05977.8 KFM11800.1 - 0.16 10.0 0.0 0.19 9.8 0.0 1.0 1 0 0 1 1 1 0 Transmembrane secretion effector Utp12 PF04003.7 KFM11802.1 - 1.8e-21 76.0 1.4 3.1e-21 75.3 1.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.27 KFM11802.1 - 9.2e-20 69.7 3.2 5.7e-08 32.3 0.3 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat TRAP_alpha PF03896.11 KFM11802.1 - 7.1 5.5 9.7 13 4.6 6.7 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Spy1 PF11357.3 KFM11803.1 - 2.6e-63 211.8 4.9 3.9e-63 211.3 3.4 1.3 1 0 0 1 1 1 1 Cell cycle regulatory protein Thyroglobulin_1 PF00086.13 KFM11804.1 - 2.2e-13 49.3 2.6 2.2e-13 49.3 1.8 2.4 2 0 0 2 2 2 2 Thyroglobulin type-1 repeat DUF4381 PF14316.1 KFM11804.1 - 0.034 14.2 0.0 0.073 13.1 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DAG1 PF05454.6 KFM11804.1 - 0.049 12.7 0.1 0.077 12.1 0.1 1.4 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) EphA2_TM PF14575.1 KFM11804.1 - 0.09 13.1 0.7 0.33 11.3 0.5 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Rifin_STEVOR PF02009.11 KFM11804.1 - 0.84 9.2 5.2 0.92 9.0 3.6 1.5 1 1 0 1 1 1 0 Rifin/stevor family MutS_V PF00488.16 KFM11805.1 - 4.3e-101 337.2 0.1 7.1e-101 336.5 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KFM11805.1 - 1e-37 129.9 2.1 1e-37 129.9 1.5 2.1 3 0 0 3 3 3 1 MutS domain III MutS_II PF05188.12 KFM11805.1 - 3.5e-22 78.9 0.3 9.4e-22 77.5 0.0 1.9 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 KFM11805.1 - 5e-19 68.2 2.7 1.3e-18 66.9 1.9 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.15 KFM11805.1 - 6.4e-05 22.9 0.0 0.00025 21.0 0.0 2.1 2 0 0 2 2 2 1 MutS domain I HK97-gp10_like PF04883.7 KFM11805.1 - 0.41 11.5 2.6 0.79 10.7 0.1 2.8 3 0 0 3 3 3 0 Bacteriophage HK97-gp10, putative tail-component BPL_N PF09825.4 KFM11805.1 - 0.95 8.1 5.2 0.54 8.9 1.6 2.1 2 1 0 2 2 2 0 Biotin-protein ligase, N terminal DUF2935 PF11155.3 KFM11805.1 - 4.1 7.4 11.7 6.2 6.9 0.6 3.7 4 1 0 4 4 4 0 Domain of unknown function (DUF2935) Ion_trans_2 PF07885.11 KFM11806.1 - 1.9e-22 78.7 20.9 4.4e-16 58.3 6.2 2.2 2 0 0 2 2 2 2 Ion channel Presenilin PF01080.12 KFM11806.1 - 0.054 12.3 4.3 0.074 11.8 3.0 1.2 1 0 0 1 1 1 0 Presenilin PPDFL PF15060.1 KFM11807.1 - 0.0019 18.1 2.6 0.01 15.8 1.8 1.9 1 1 0 1 1 1 1 Differentiation and proliferation regulator zf-H2C2_2 PF13465.1 KFM11808.1 - 8e-26 89.0 28.4 5.7e-09 35.8 0.2 5.7 5 0 0 5 5 5 5 Zinc-finger double domain zf-C2H2 PF00096.21 KFM11808.1 - 8e-25 85.6 43.3 4.2e-06 26.7 0.3 5.6 6 0 0 6 6 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM11808.1 - 1.6e-17 62.4 35.9 0.00039 20.5 1.4 6.1 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM11808.1 - 1.1e-14 54.0 28.1 0.00023 21.2 0.2 6.2 5 1 1 6 6 6 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFM11808.1 - 2.7e-13 49.3 31.2 0.00035 20.3 3.1 5.4 5 0 0 5 5 5 5 C2H2-type zinc finger zf-Di19 PF05605.7 KFM11808.1 - 2.6e-07 30.6 18.5 0.0062 16.6 2.7 3.7 3 1 0 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 KFM11808.1 - 7e-07 29.2 27.5 0.0055 16.8 0.3 5.9 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-BED PF02892.10 KFM11808.1 - 5.8e-06 25.9 26.6 0.18 11.6 1.4 5.5 3 1 2 5 5 5 4 BED zinc finger zf-C2HC_2 PF13913.1 KFM11808.1 - 0.00024 20.6 17.2 0.49 10.1 0.3 5.4 5 0 0 5 5 5 3 zinc-finger of a C2HC-type Elf1 PF05129.8 KFM11808.1 - 0.00033 20.3 17.1 0.023 14.3 0.5 3.2 2 1 1 3 3 3 2 Transcription elongation factor Elf1 like Rpr2 PF04032.11 KFM11808.1 - 0.0036 17.1 13.3 0.057 13.2 0.4 2.4 2 0 0 2 2 2 2 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C2H2_2 PF12756.2 KFM11808.1 - 0.0039 17.2 22.2 2.3 8.3 0.9 5.1 1 1 3 4 4 4 2 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.5 KFM11808.1 - 0.14 12.1 26.1 0.79 9.7 1.6 4.8 4 1 0 4 4 4 0 Zinc ribbon domain PyrI_C PF02748.10 KFM11808.1 - 0.17 11.3 18.2 2.6 7.5 0.9 4.6 4 1 1 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Trm112p PF03966.11 KFM11808.1 - 0.2 12.0 2.1 10 6.5 0.4 3.6 3 1 0 3 3 3 0 Trm112p-like protein Zn_Tnp_IS1595 PF12760.2 KFM11808.1 - 1.2 9.0 26.8 0.063 13.0 4.2 4.0 2 2 2 4 4 4 0 Transposase zinc-ribbon domain zf-CHCC PF10276.4 KFM11808.1 - 2.1 8.2 13.2 2.7 7.8 1.4 4.2 4 0 0 4 4 4 0 Zinc-finger domain zf-CHY PF05495.7 KFM11808.1 - 2.8 8.1 26.7 2.1 8.5 5.0 2.5 2 1 0 2 2 2 0 CHY zinc finger zf-AN1 PF01428.11 KFM11808.1 - 3.9 7.4 24.7 11 6.0 0.1 5.3 5 0 0 5 5 5 0 AN1-like Zinc finger zinc_ribbon_5 PF13719.1 KFM11808.1 - 5.3 6.7 18.5 2.7 7.6 0.2 4.8 5 0 0 5 5 5 0 zinc-ribbon domain zf-HYPF PF07503.7 KFM11808.1 - 9.9 5.6 14.5 2.8 7.4 0.6 3.4 3 1 0 3 3 3 0 HypF finger Yae1_N PF09811.4 KFM11809.1 - 1.2e-12 47.1 44.6 0.0011 18.4 3.6 4.6 1 1 2 3 3 3 3 Essential protein Yae1, N terminal Voltage_CLC PF00654.15 KFM11810.1 - 8.7e-23 80.9 7.8 9.9e-23 80.7 5.4 1.0 1 0 0 1 1 1 1 Voltage gated chloride channel MtrG PF04210.8 KFM11810.1 - 0.12 12.0 1.6 0.21 11.2 1.1 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G UQ_con PF00179.21 KFM11811.1 - 1.2e-18 66.8 0.0 1.3e-18 66.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KFM11811.1 - 0.0093 15.8 0.0 0.0099 15.7 0.0 1.3 1 0 0 1 1 1 1 RWD domain MCM PF00493.18 KFM11812.1 - 2.5e-135 450.5 0.1 4.7e-135 449.6 0.0 1.4 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 KFM11812.1 - 2.2e-26 92.7 0.4 8.4e-26 90.8 0.3 2.1 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KFM11812.1 - 2.7e-08 33.2 0.0 1.2e-05 24.5 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KFM11812.1 - 4e-08 33.0 0.1 3.1e-07 30.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KFM11812.1 - 5.1e-05 22.8 0.0 9.8e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KFM11812.1 - 0.0092 15.4 0.0 3.5 7.0 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA PF00004.24 KFM11812.1 - 0.013 15.6 0.0 0.046 13.9 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) HypA PF01155.14 KFM11812.1 - 0.061 13.0 1.3 0.12 12.0 0.1 2.0 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family NTPase_1 PF03266.10 KFM11812.1 - 0.082 12.6 0.7 4.1 7.0 0.0 3.1 3 1 1 4 4 4 0 NTPase Elf1 PF05129.8 KFM11812.1 - 0.11 12.1 0.7 0.43 10.3 0.5 2.0 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like NUC194 PF08163.7 KFM11813.1 - 3.6e-185 615.4 0.8 7e-185 614.5 0.5 1.5 1 0 0 1 1 1 1 NUC194 domain FAT PF02259.18 KFM11813.1 - 4.8e-71 239.5 9.4 4.8e-71 239.5 6.5 2.8 3 0 0 3 3 3 1 FAT domain PI3_PI4_kinase PF00454.22 KFM11813.1 - 1.5e-58 198.0 1.7 2.1e-58 197.5 0.1 2.1 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 KFM11813.1 - 5e-11 41.8 0.1 1.2e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 FATC domain TPR_1 PF00515.23 KFM11813.1 - 0.11 12.1 3.3 3.1 7.5 1.0 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFM11813.1 - 0.19 11.5 1.7 29 4.7 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFM11813.1 - 0.19 12.4 0.8 6.5 7.5 0.5 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 KFM11813.1 - 0.38 10.8 8.3 3.1 7.9 1.4 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4503 PF14951.1 KFM11814.1 - 2.8e-155 516.2 8.2 4e-155 515.7 5.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4503) DUF4502 PF14950.1 KFM11814.1 - 2e-46 158.8 0.2 2.9e-46 158.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4502) DUF4502 PF14950.1 KFM11815.1 - 1.2e-35 123.3 15.8 1.5e-35 123.0 11.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4502) CDP-OH_P_transf PF01066.16 KFM11816.1 - 1.9e-11 44.1 23.3 3.2e-10 40.2 15.7 3.2 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase EB1 PF03271.12 KFM11817.1 - 7.2e-16 57.9 0.1 1.7e-15 56.7 0.1 1.7 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 KFM11817.1 - 2.8e-11 43.4 0.9 3.9e-11 42.9 0.3 1.5 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFM11817.1 - 0.0026 17.3 0.1 0.0069 16.0 0.1 1.7 2 0 0 2 2 2 1 CAMSAP CH domain Suppressor_APC PF11414.3 KFM11817.1 - 0.018 14.7 0.4 0.033 13.9 0.3 1.4 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein MIS13 PF08202.6 KFM11817.1 - 0.027 13.5 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 Mis12-Mtw1 protein family COG4 PF08318.7 KFM11817.1 - 0.065 11.9 0.1 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 COG4 transport protein EF-hand_2 PF09068.6 KFM11818.1 - 1.5e-40 138.2 0.9 8.6e-40 135.7 0.5 2.2 2 0 0 2 2 2 1 EF hand EF-hand_3 PF09069.6 KFM11818.1 - 4.1e-35 119.7 0.1 1.3e-34 118.1 0.0 1.9 2 0 0 2 2 2 1 EF-hand ZZ PF00569.12 KFM11818.1 - 3.2e-11 42.5 8.9 7.4e-11 41.4 6.2 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type Seryl_tRNA_N PF02403.17 KFM11818.1 - 0.015 15.3 7.7 0.059 13.3 5.4 2.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Tnp_zf-ribbon_2 PF13842.1 KFM11818.1 - 0.45 10.9 7.5 1 9.8 5.2 1.7 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon DUF342 PF03961.8 KFM11818.1 - 0.69 8.2 5.2 1.3 7.3 3.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 KFM11818.1 - 2.1 7.2 12.0 5.5 5.9 8.3 1.7 1 0 0 1 1 1 0 Autophagy protein Apg6 BEN PF10523.4 KFM11819.1 - 0.068 13.2 0.2 2.3 8.3 0.0 2.7 2 0 0 2 2 2 0 BEN domain zf-H2C2 PF09337.5 KFM11819.1 - 0.078 12.4 0.1 0.27 10.6 0.0 2.0 2 0 0 2 2 2 0 His(2)-Cys(2) zinc finger ASXH PF13919.1 KFM11821.1 - 9e-48 161.5 1.0 9e-48 161.5 0.7 2.6 2 0 0 2 2 2 1 Asx homology domain PHD_3 PF13922.1 KFM11821.1 - 2.4e-24 85.3 9.3 2.4e-24 85.3 6.5 3.8 2 0 0 2 2 2 1 PHD domain of transcriptional enhancer, Asx HARE-HTH PF05066.8 KFM11821.1 - 0.0016 18.7 0.0 0.0038 17.5 0.0 1.7 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain zf-RING-like PF08746.6 KFM11822.1 - 6.2 6.8 6.2 0.49 10.4 0.1 2.3 3 0 0 3 3 3 0 RING-like domain Ras PF00071.17 KFM11823.1 - 1.2e-44 151.5 0.1 1.5e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM11823.1 - 2.6e-11 44.0 0.0 4.4e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM11823.1 - 9.3e-09 34.7 0.1 1e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFM11823.1 - 3.5e-05 23.3 0.0 4.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFM11823.1 - 0.0012 18.0 0.1 0.0017 17.5 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region CABIT PF12736.2 KFM11824.1 - 1.3e-51 175.0 0.6 1.9e-51 174.5 0.4 1.3 1 0 0 1 1 1 1 Cell-cycle sustaining, positive selection, SAM_1 PF00536.25 KFM11824.1 - 0.00063 19.8 0.1 0.0012 18.9 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Astacin PF01400.19 KFM11825.1 - 4.4e-72 241.4 0.1 7.7e-72 240.6 0.1 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) MAM PF00629.18 KFM11825.1 - 2.8e-40 137.7 0.1 2.2e-39 134.8 0.1 2.2 2 0 0 2 2 2 1 MAM domain MATH PF00917.21 KFM11825.1 - 5e-28 97.7 0.0 1e-27 96.7 0.0 1.6 1 0 0 1 1 1 1 MATH domain EGF PF00008.22 KFM11825.1 - 6.9e-07 29.1 1.8 2e-06 27.6 1.2 1.9 1 0 0 1 1 1 1 EGF-like domain DAG1 PF05454.6 KFM11825.1 - 0.047 12.8 0.1 0.068 12.3 0.1 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Peptidase_M91 PF14891.1 KFM11825.1 - 0.19 11.7 0.0 0.35 10.9 0.0 1.3 1 0 0 1 1 1 0 Effector protein EGF_2 PF07974.8 KFM11825.1 - 0.49 10.6 4.6 1.5 9.0 3.2 1.8 1 0 0 1 1 1 0 EGF-like domain zf-Di19 PF05605.7 KFM11826.1 - 4.7e-13 49.0 8.3 4.7e-13 49.0 5.8 3.3 3 1 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4_3 PF13920.1 KFM11826.1 - 0.037 13.7 1.2 0.037 13.7 0.9 3.6 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM11826.1 - 0.056 13.2 4.2 0.056 13.2 2.9 3.6 2 1 0 2 2 2 0 Ring finger domain PRP21_like_P PF12230.3 KFM11826.1 - 0.086 12.3 0.6 2.8 7.3 0.1 2.2 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein Glyco_transf_7N PF13733.1 KFM11827.1 - 4.9e-43 145.7 0.0 7.3e-43 145.2 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.9 KFM11827.1 - 1e-27 95.3 0.9 1.9e-27 94.5 0.6 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFM11827.1 - 5e-08 32.3 0.3 0.00044 19.4 0.1 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Transthyretin PF00576.16 KFM11828.1 - 4.6e-39 132.7 0.1 5.5e-39 132.5 0.1 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family Cadherin PF00028.12 KFM11829.1 - 4.7e-58 193.4 4.6 3e-19 69.0 0.0 5.3 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.12 KFM11829.1 - 2.1e-07 31.1 0.0 3.9e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.7 KFM11829.1 - 6.1e-05 22.5 0.0 0.29 10.7 0.0 3.5 2 1 1 3 3 3 2 Cadherin-like Cadherin PF00028.12 KFM11831.1 - 1.1e-63 211.5 3.0 3.3e-15 56.1 0.0 6.2 7 0 0 7 7 7 5 Cadherin domain Cadherin_C PF01049.12 KFM11831.1 - 1.2e-18 67.6 0.5 1.2e-17 64.3 0.3 2.4 1 1 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_pro PF08758.6 KFM11831.1 - 5.1e-16 58.2 3.3 2.5e-14 52.7 0.3 4.4 5 0 0 5 5 5 1 Cadherin prodomain like Cadherin_2 PF08266.7 KFM11831.1 - 0.00075 19.0 0.0 0.32 10.5 0.0 3.5 4 0 0 4 4 4 1 Cadherin-like Cadherin PF00028.12 KFM11834.1 - 7.8e-91 298.5 2.1 5.4e-23 81.0 0.1 5.8 6 0 0 6 6 6 5 Cadherin domain Cadherin_C PF01049.12 KFM11834.1 - 7.8e-55 185.0 1.5 1.4e-54 184.1 1.0 1.4 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_pro PF08758.6 KFM11834.1 - 6e-29 99.6 0.2 2.6e-28 97.6 0.0 2.1 2 0 0 2 2 2 1 Cadherin prodomain like He_PIG PF05345.7 KFM11834.1 - 8.3e-05 22.5 8.8 0.7 9.9 0.3 6.1 5 1 1 6 6 6 2 Putative Ig domain Cadherin_2 PF08266.7 KFM11834.1 - 0.0062 16.0 0.0 4.9 6.7 0.0 3.3 3 0 0 3 3 3 1 Cadherin-like Prok-E2_A PF14457.1 KFM11834.1 - 0.019 14.4 0.1 0.086 12.2 0.0 1.9 2 0 0 2 2 2 0 Prokaryotic E2 family A DUF2207 PF09972.4 KFM11834.1 - 0.046 12.2 0.0 0.073 11.6 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SIT PF15330.1 KFM11834.1 - 0.18 11.9 0.1 0.66 10.1 0.0 1.9 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Rifin_STEVOR PF02009.11 KFM11834.1 - 0.4 10.2 1.5 0.63 9.6 1.1 1.2 1 0 0 1 1 1 0 Rifin/stevor family Big_3_4 PF13754.1 KFM11834.1 - 0.48 10.7 14.0 0.5 10.7 0.3 5.0 5 1 1 6 6 6 0 Bacterial Ig-like domain (group 3) Sulfotransfer_2 PF03567.9 KFM11836.1 - 5.3e-61 206.4 2.0 7.1e-61 206.0 1.4 1.2 1 0 0 1 1 1 1 Sulfotransferase family DUF4368 PF14287.1 KFM11836.1 - 0.14 11.9 1.2 3.5 7.5 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4368) MIP PF00230.15 KFM11837.1 - 3.1e-72 242.7 14.4 3.8e-72 242.4 10.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein RVT_1 PF00078.22 KFM11839.1 - 0.057 12.7 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) BTB_2 PF02214.17 KFM11840.1 - 2.2e-17 63.0 0.0 3.4e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain TAF4 PF05236.9 KFM11841.1 - 4.9e-59 199.7 9.0 7.5e-59 199.1 6.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family TAFH PF07531.9 KFM11841.1 - 2.1e-37 126.6 2.9 8.3e-37 124.7 2.0 2.1 1 0 0 1 1 1 1 NHR1 homology to TAF zf-C2H2 PF00096.21 KFM11843.1 - 3.4e-52 171.7 223.9 0.00069 19.8 3.1 30.7 31 0 0 31 31 31 25 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM11843.1 - 1.8e-49 162.4 203.6 0.0022 18.1 0.5 30.2 31 0 0 31 31 31 24 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFM11843.1 - 2.6e-35 118.9 184.7 3.9e-06 26.8 0.6 30.2 33 0 0 33 33 33 19 Zinc-finger double domain zf-Di19 PF05605.7 KFM11843.1 - 1.3e-25 89.2 167.7 8e-05 22.6 2.3 19.7 16 3 4 20 20 20 12 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 KFM11843.1 - 3.3e-21 74.4 163.9 3.7e-05 23.4 0.3 25.1 27 1 1 28 28 28 14 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM11843.1 - 9.4e-17 60.6 154.4 0.00091 19.3 0.4 24.5 25 1 1 26 26 26 13 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFM11843.1 - 4.1e-06 26.8 167.9 0.082 13.0 0.4 24.5 8 6 14 23 23 23 13 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KFM11843.1 - 0.00053 20.0 6.4 0.0074 16.4 0.8 22.4 25 0 0 25 25 25 9 Zinc-finger of C2H2 type UPF0029 PF01205.14 KFM11845.1 - 2.9e-33 113.8 0.0 4.3e-33 113.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 KFM11845.1 - 1.1e-17 63.9 0.8 1.1e-17 63.9 0.6 1.8 2 1 0 2 2 2 1 RWD domain DUF677 PF05055.7 KFM11845.1 - 0.034 12.8 0.0 0.048 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Oxysterol_BP PF01237.13 KFM11846.1 - 1.2e-146 487.8 0.6 1.8e-146 487.2 0.4 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein Ank PF00023.25 KFM11846.1 - 1.1e-30 103.9 2.9 6.2e-11 41.5 0.1 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 KFM11846.1 - 5.6e-30 102.6 3.3 1.8e-13 50.2 0.2 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 KFM11846.1 - 1.7e-28 98.7 1.7 2.1e-16 60.0 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFM11846.1 - 5.2e-23 80.9 2.4 5.3e-06 26.7 0.0 5.2 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM11846.1 - 8.8e-23 78.1 1.1 1.3e-06 28.0 0.0 5.1 4 0 0 4 4 4 3 Ankyrin repeat PH PF00169.24 KFM11846.1 - 0.004 17.3 2.0 0.03 14.5 0.2 2.9 2 1 1 3 3 3 1 PH domain PH_11 PF15413.1 KFM11846.1 - 0.087 13.0 0.2 0.087 13.0 0.1 3.4 3 0 0 3 3 3 0 Pleckstrin homology domain SHS2_FTSA PF02491.15 KFM11846.1 - 0.11 12.3 0.4 0.61 10.0 0.0 2.3 2 0 0 2 2 2 0 SHS2 domain inserted in FTSA HpcH_HpaI PF03328.9 KFM11847.1 - 0.022 13.6 0.1 0.04 12.8 0.0 1.4 2 0 0 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family DUF3808 PF10300.4 KFM11848.1 - 1.9e-127 425.6 6.8 2.3e-127 425.4 4.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.12 KFM11848.1 - 0.00014 21.5 3.1 0.32 10.9 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFM11848.1 - 0.00019 21.3 0.1 4 7.4 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFM11848.1 - 0.001 18.6 0.1 1.5 8.5 0.0 2.8 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KFM11848.1 - 0.0025 17.3 1.6 0.24 11.0 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFM11848.1 - 0.04 13.7 0.1 0.44 10.4 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFM11848.1 - 0.066 13.5 0.1 36 4.7 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KFM11848.1 - 0.12 12.8 0.9 77 4.0 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Laminin_EGF PF00053.19 KFM11849.1 - 3.1e-95 311.9 311.1 3.8e-10 39.5 7.9 16.8 15 2 1 17 17 17 15 Laminin EGF-like (Domains III and V) Laminin_G_2 PF02210.19 KFM11849.1 - 5.7e-83 275.3 0.0 6e-27 94.2 0.0 6.2 6 0 0 6 6 6 5 Laminin G domain Laminin_G_1 PF00054.18 KFM11849.1 - 7.5e-62 207.1 0.0 4.7e-21 75.1 0.0 6.1 5 1 0 5 5 5 4 Laminin G domain Laminin_N PF00055.12 KFM11849.1 - 1.8e-57 194.0 0.0 4.1e-57 192.8 0.0 1.6 1 0 0 1 1 1 1 Laminin N-terminal (Domain VI) Laminin_I PF06008.9 KFM11849.1 - 4e-50 170.5 32.2 4e-50 170.5 22.3 3.5 2 1 0 3 3 3 1 Laminin Domain I Laminin_II PF06009.7 KFM11849.1 - 3.7e-37 127.1 0.9 3.7e-37 127.1 0.6 5.9 3 2 3 6 6 6 1 Laminin Domain II Laminin_B PF00052.13 KFM11849.1 - 2.2e-19 69.4 0.0 5.4e-19 68.1 0.0 1.7 1 0 0 1 1 1 1 Laminin B (Domain IV) Laminin_G_3 PF13385.1 KFM11849.1 - 2.5e-18 66.8 0.0 3.4e-07 30.6 0.0 3.8 4 0 0 4 4 4 2 Concanavalin A-like lectin/glucanases superfamily Polysacc_lyase PF14099.1 KFM11849.1 - 0.34 10.5 0.0 22 4.6 0.0 2.4 2 0 0 2 2 2 0 Polysaccharide lyase Activator-TraM PF11657.3 KFM11849.1 - 0.42 10.0 11.1 0.0086 15.5 1.8 2.4 2 1 1 3 3 3 0 Transcriptional activator TraM SNARE PF05739.14 KFM11849.1 - 1.2 8.8 12.5 0.06 13.0 0.8 4.0 4 0 0 4 4 4 0 SNARE domain Ank PF00023.25 KFM11850.1 - 1.2e-54 179.4 7.5 4.1e-09 35.7 0.0 8.3 8 0 0 8 8 8 8 Ankyrin repeat Ank_2 PF12796.2 KFM11850.1 - 2.1e-54 181.8 2.0 3.4e-16 59.3 0.0 4.2 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFM11850.1 - 6.3e-52 173.0 9.2 9.8e-10 38.6 0.0 6.6 2 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM11850.1 - 3.3e-36 119.6 1.8 4.8e-05 23.2 0.0 8.1 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.1 KFM11850.1 - 3.8e-32 109.5 11.8 2.8e-10 40.1 0.0 8.0 1 1 7 8 8 8 7 Ankyrin repeats (many copies) Shigella_OspC PF06128.6 KFM11850.1 - 0.018 14.5 0.1 0.98 8.8 0.0 3.2 2 1 2 4 4 4 0 Shigella flexneri OspC protein Patched PF02460.13 KFM11851.1 - 9.3e-85 285.1 25.6 8.1e-84 282.0 17.8 2.1 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 KFM11851.1 - 2.6e-55 186.1 6.1 2.6e-55 186.1 4.2 2.6 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 KFM11851.1 - 8e-05 21.4 3.9 8e-05 21.4 2.7 2.3 2 0 0 2 2 2 1 MMPL family ACR_tran PF00873.14 KFM11851.1 - 0.00071 17.1 7.0 0.00071 17.1 4.8 2.0 2 1 1 3 3 3 1 AcrB/AcrD/AcrF family Mic1 PF07035.7 KFM11852.1 - 5e-75 250.4 0.4 9.8e-75 249.5 0.3 1.5 1 0 0 1 1 1 1 Colon cancer-associated protein Mic1-like RIO1 PF01163.17 KFM11853.1 - 8.1e-76 253.5 0.3 8.1e-76 253.5 0.2 1.7 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.20 KFM11853.1 - 2.7e-05 23.4 0.1 5.1e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KFM11853.1 - 0.00015 20.9 0.1 0.00057 19.0 0.1 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFM11853.1 - 0.0018 18.0 0.1 0.04 13.6 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFM11853.1 - 0.021 14.3 1.3 0.05 13.1 0.2 2.1 2 1 1 3 3 3 0 Choline/ethanolamine kinase DUF457 PF04307.9 KFM11854.1 - 1.4 8.2 8.0 2.1 7.6 4.8 2.1 1 1 0 1 1 1 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) Cyclin_N PF00134.18 KFM11855.1 - 3.9e-08 32.8 0.2 5.7e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain CtIP_N PF10482.4 KFM11856.1 - 2.4e-54 182.2 20.0 9.6e-54 180.2 13.9 2.1 1 0 0 1 1 1 1 Tumour-suppressor protein CtIP N-terminal domain SAE2 PF08573.5 KFM11856.1 - 1e-09 38.9 4.9 1e-09 38.9 3.4 5.4 4 2 0 4 4 4 1 DNA repair protein endonuclease SAE2/CtIP C-terminus DUF904 PF06005.7 KFM11856.1 - 0.012 15.9 3.1 0.012 15.9 2.2 4.2 3 1 0 3 3 3 0 Protein of unknown function (DUF904) Chitin_synth_1N PF08407.6 KFM11856.1 - 0.031 13.9 0.0 0.16 11.7 0.0 2.3 1 0 0 1 1 1 0 Chitin synthase N-terminal GATA PF00320.22 KFM11857.1 - 2.2e-30 103.6 21.8 1.5e-16 59.4 2.9 3.0 3 0 0 3 3 3 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 KFM11857.1 - 4.3e-08 32.3 5.4 0.00098 18.4 0.3 2.3 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.5 KFM11857.1 - 0.00019 21.2 0.7 0.21 11.5 0.2 3.5 3 0 0 3 3 3 1 Zinc ribbon domain eIF-5_eIF-2B PF01873.12 KFM11857.1 - 0.0082 15.7 4.9 0.62 9.7 0.2 2.3 2 0 0 2 2 2 2 Domain found in IF2B/IF5 Elf1 PF05129.8 KFM11857.1 - 0.011 15.4 5.3 0.53 10.0 0.0 2.9 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like OrfB_Zn_ribbon PF07282.6 KFM11857.1 - 0.052 13.2 0.2 0.052 13.2 0.1 3.5 3 1 1 4 4 4 0 Putative transposase DNA-binding domain Auxin_repressed PF05564.7 KFM11857.1 - 0.11 13.1 4.0 0.19 12.3 2.8 1.3 1 0 0 1 1 1 0 Dormancy/auxin associated protein DZR PF12773.2 KFM11857.1 - 0.17 11.7 10.5 1.7 8.5 5.2 3.0 1 1 1 2 2 2 0 Double zinc ribbon Prim_Zn_Ribbon PF08273.7 KFM11857.1 - 0.25 11.4 9.2 0.46 10.6 1.9 2.6 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase BaffR-Tall_bind PF09256.5 KFM11857.1 - 0.26 10.9 3.7 1.5 8.4 0.0 3.2 3 0 0 3 3 3 0 BAFF-R, TALL-1 binding Zn_Tnp_IS1595 PF12760.2 KFM11857.1 - 0.39 10.5 9.6 0.27 11.0 0.3 2.7 2 1 1 3 3 3 0 Transposase zinc-ribbon domain DUF2387 PF09526.5 KFM11857.1 - 0.59 10.1 5.1 16 5.5 0.2 3.0 2 1 1 3 3 3 0 Probable metal-binding protein (DUF2387) zf-CHY PF05495.7 KFM11857.1 - 0.95 9.6 5.1 7.1 6.8 0.6 2.5 2 1 0 2 2 2 0 CHY zinc finger Cytochrome_C7 PF14522.1 KFM11857.1 - 2.7 7.6 11.1 1.1 8.8 3.4 2.7 1 1 1 2 2 2 0 Cytochrome c7 Cytochrom_c3_2 PF14537.1 KFM11857.1 - 2.9 8.2 8.5 0.91 9.9 2.3 2.4 1 1 1 2 2 2 0 Cytochrome c3 gerPA PF10676.4 KFM11857.1 - 5 7.0 7.8 2.8 7.8 1.7 2.2 2 0 0 2 2 2 0 Spore germination protein gerPA/gerPF FYVE PF01363.16 KFM11857.1 - 5.9 6.8 7.1 31 4.5 4.9 2.4 1 1 0 1 1 1 0 FYVE zinc finger Ank PF00023.25 KFM11858.1 - 2.2e-55 181.8 16.6 2e-08 33.6 0.0 9.7 10 1 0 10 10 10 8 Ankyrin repeat Ank_2 PF12796.2 KFM11858.1 - 1.7e-54 182.1 16.8 1.2e-16 60.7 0.0 5.7 2 1 4 6 6 6 4 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFM11858.1 - 5.6e-48 159.8 16.2 2.8e-12 46.4 0.0 7.3 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFM11858.1 - 7.3e-41 137.8 14.6 1.4e-11 44.5 0.1 7.6 3 2 6 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM11858.1 - 4.7e-32 106.8 17.9 0.00028 20.8 0.0 10.1 11 0 0 11 11 11 6 Ankyrin repeat MIB_HERC2 PF06701.8 KFM11858.1 - 1.1e-28 99.0 6.6 3e-28 97.6 3.2 2.9 2 0 0 2 2 2 1 Mib_herc2 zf-C3HC4_3 PF13920.1 KFM11858.1 - 4.6e-28 96.6 59.9 4.2e-11 42.3 9.5 4.7 4 1 1 5 5 5 3 Zinc finger, C3HC4 type (RING finger) ZZ PF00569.12 KFM11858.1 - 4.7e-11 42.0 8.2 4.7e-11 42.0 5.7 3.6 3 0 0 3 3 3 1 Zinc finger, ZZ type zf-C3HC4_2 PF13923.1 KFM11858.1 - 7.3e-05 22.7 62.1 0.0019 18.2 7.0 5.0 4 0 0 4 4 4 3 Zinc finger, C3HC4 type (RING finger) Abhydrolase_6 PF12697.2 KFM11859.1 - 2.8e-13 50.3 0.0 3.7e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFM11859.1 - 2.7e-06 27.1 0.0 6.9e-06 25.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFM11859.1 - 4.1e-06 26.5 0.0 9.4e-06 25.3 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 KFM11859.1 - 0.082 12.3 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Acetyltransf_13 PF13880.1 KFM11860.1 - 8.4e-32 108.7 0.0 1.7e-31 107.7 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 KFM11860.1 - 5e-17 61.1 0.1 1.1e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Pkinase PF00069.20 KFM11863.1 - 4.3e-61 206.3 0.0 4.3e-61 206.3 0.0 3.4 4 0 0 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM11863.1 - 3.3e-30 105.0 0.0 1.6e-29 102.7 0.0 2.3 1 0 0 1 1 1 1 Protein tyrosine kinase Rho_Binding PF08912.6 KFM11863.1 - 1.7e-23 82.6 14.3 1.7e-23 82.6 9.9 11.7 5 2 6 11 11 11 1 Rho Binding HR1 PF02185.11 KFM11863.1 - 2.6e-11 43.1 14.8 2.6e-11 43.1 10.3 10.8 7 3 3 10 10 10 1 Hr1 repeat PH PF00169.24 KFM11863.1 - 2.2e-06 27.8 0.1 2.2e-06 27.8 0.0 3.8 3 2 0 3 3 3 1 PH domain Pkinase_C PF00433.19 KFM11863.1 - 3.8e-05 24.1 2.3 0.00011 22.6 1.6 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Myosin_tail_1 PF01576.14 KFM11863.1 - 0.00036 18.4 171.5 0.00082 17.2 25.1 4.3 1 1 3 4 4 4 3 Myosin tail C1_1 PF00130.17 KFM11863.1 - 0.00048 19.7 5.9 0.0011 18.6 4.1 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) APH PF01636.18 KFM11863.1 - 0.0013 18.5 0.2 0.01 15.5 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family UCH PF00443.24 KFM11864.1 - 5.7e-59 199.4 0.7 6.7e-59 199.1 0.5 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFM11864.1 - 6e-18 65.3 6.1 1.7e-17 63.8 4.2 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 KFM11864.1 - 0.00042 19.6 0.0 0.0011 18.3 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Peptidase_C98 PF15499.1 KFM11864.1 - 0.012 14.9 1.4 0.16 11.2 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase PFEMP PF03011.10 KFM11864.1 - 2.2 8.6 7.3 5.2 7.3 0.1 2.8 3 0 0 3 3 3 0 PFEMP DBL domain efThoc1 PF11957.3 KFM11865.1 - 2.8e-154 514.2 6.3 4e-154 513.7 4.4 1.2 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Death PF00531.17 KFM11865.1 - 7e-18 64.1 2.2 1.7e-17 62.9 0.4 2.5 3 0 0 3 3 3 1 Death domain Collagen PF01391.13 KFM11866.1 - 5.1e-24 83.5 99.7 1.2e-09 37.5 22.7 3.2 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) Lectin_C PF00059.16 KFM11866.1 - 6.7e-21 74.9 1.8 6.7e-21 74.9 1.3 2.4 2 0 0 2 2 2 1 Lectin C-type domain Reo_sigmaC PF04582.7 KFM11866.1 - 0.0012 18.1 34.1 0.039 13.1 6.3 3.7 1 1 3 4 4 4 3 Reovirus sigma C capsid protein Filament PF00038.16 KFM11866.1 - 0.0022 17.5 29.2 0.0022 17.5 20.2 2.0 1 1 1 2 2 2 1 Intermediate filament protein DUF1495 PF07381.6 KFM11866.1 - 0.044 13.4 0.1 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain (DUF1495) Fib_alpha PF08702.5 KFM11866.1 - 0.14 12.3 36.3 0.086 12.9 4.5 3.8 1 1 2 4 4 4 0 Fibrinogen alpha/beta chain family IncA PF04156.9 KFM11866.1 - 0.14 11.7 30.9 8.1 5.9 3.2 3.9 2 1 0 2 2 2 0 IncA protein DUF1664 PF07889.7 KFM11866.1 - 0.29 10.9 28.1 2.2 8.1 5.3 4.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Spc7 PF08317.6 KFM11866.1 - 0.37 9.4 34.7 0.34 9.5 11.8 3.3 1 1 2 3 3 3 0 Spc7 kinetochore protein WEMBL PF05701.6 KFM11866.1 - 3.4 6.0 29.4 2.1 6.7 16.3 2.2 1 1 1 2 2 2 0 Weak chloroplast movement under blue light NPV_P10 PF05531.7 KFM11866.1 - 4.5 7.5 27.4 0.52 10.5 3.6 5.4 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Clusterin PF01093.12 KFM11868.1 - 2.7e-136 454.8 10.4 3.1e-136 454.6 7.2 1.0 1 0 0 1 1 1 1 Clusterin DUF3482 PF11981.3 KFM11868.1 - 0.0064 15.7 2.7 0.012 14.8 1.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3482) ALIX_LYPXL_bnd PF13949.1 KFM11868.1 - 0.021 13.8 6.1 0.017 14.0 2.6 2.1 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV Sulfatase_C PF14707.1 KFM11868.1 - 0.19 12.0 6.7 7.8 6.8 0.0 3.5 2 1 1 3 3 3 0 C-terminal region of aryl-sulfatase eIF-5a PF01287.15 KFM11868.1 - 0.51 10.3 7.6 0.51 10.3 0.2 3.3 2 1 1 3 3 3 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Thymidylat_synt PF00303.14 KFM11869.1 - 2.8e-111 370.8 0.0 3.1e-111 370.6 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Pkinase_Tyr PF07714.12 KFM11870.1 - 7.3e-94 313.6 0.0 9.2e-94 313.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM11870.1 - 4.3e-50 170.2 0.0 6.2e-50 169.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 KFM11870.1 - 1.2e-28 98.6 0.2 2.5e-28 97.6 0.1 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.23 KFM11870.1 - 8.9e-21 73.0 0.4 3.8e-20 71.0 0.1 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KFM11870.1 - 6.9e-16 57.5 0.0 1.8e-15 56.2 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFM11870.1 - 4.4e-12 45.3 0.0 1.2e-11 43.9 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain APH PF01636.18 KFM11870.1 - 0.011 15.4 0.0 0.064 12.9 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family SH3_3 PF08239.6 KFM11870.1 - 0.028 14.6 0.1 0.081 13.1 0.1 1.8 1 0 0 1 1 1 0 Bacterial SH3 domain FGF PF00167.13 KFM11874.1 - 9.4e-36 122.2 0.1 1.1e-35 121.9 0.1 1.1 1 0 0 1 1 1 1 Fibroblast growth factor FRG1 PF06229.7 KFM11874.1 - 0.13 11.6 0.2 9.8 5.5 0.1 2.1 1 1 1 2 2 2 0 FRG1-like family Nucleoplasmin PF03066.10 KFM11875.1 - 7e-43 145.6 25.8 3.3e-42 143.5 17.8 2.0 1 1 0 1 1 1 1 Nucleoplasmin TFIIF_alpha PF05793.7 KFM11875.1 - 0.00014 20.4 17.9 0.00014 20.3 12.4 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CENP-T PF15511.1 KFM11875.1 - 0.0003 20.1 10.2 0.00031 20.1 7.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T SGT1 PF07093.6 KFM11875.1 - 0.0007 18.1 7.8 0.00077 17.9 5.4 1.3 1 0 0 1 1 1 1 SGT1 protein BSP_II PF05432.6 KFM11875.1 - 0.0081 15.4 13.0 0.015 14.6 9.0 1.5 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Daxx PF03344.10 KFM11875.1 - 0.025 13.0 16.8 0.033 12.7 11.6 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 KFM11875.1 - 0.033 12.1 27.5 0.046 11.6 19.0 1.1 1 0 0 1 1 1 0 Nop14-like family Spt5_N PF11942.3 KFM11875.1 - 0.36 11.4 26.8 0.12 12.9 10.8 2.8 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal Lin-8 PF03353.10 KFM11875.1 - 0.46 9.7 12.1 0.63 9.2 8.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist NOA36 PF06524.7 KFM11875.1 - 0.64 9.2 14.4 1.2 8.3 10.0 1.4 1 0 0 1 1 1 0 NOA36 protein Hid1 PF12722.2 KFM11875.1 - 0.99 7.0 5.1 1.2 6.7 3.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.9 KFM11875.1 - 1 7.2 13.7 1.4 6.8 9.5 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 KFM11875.1 - 1.8 7.8 22.1 2.9 7.0 15.4 1.3 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.6 KFM11875.1 - 3.6 5.5 5.9 4.9 5.1 4.1 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 IBN_N PF03810.14 KFM11876.1 - 1.5e-08 34.4 1.7 1.7e-07 31.0 0.1 3.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain I-set PF07679.11 KFM11877.1 - 1.2e-13 50.7 0.0 1.8e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM11877.1 - 1.5e-06 28.2 0.0 3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFM11877.1 - 4.5e-05 23.4 0.0 0.00026 21.0 0.0 2.2 2 1 0 2 2 2 1 Immunoglobulin domain V-set PF07686.12 KFM11877.1 - 0.00029 20.7 0.0 0.00068 19.5 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin V-set domain Kazal_1 PF00050.16 KFM11877.1 - 0.0022 17.9 19.1 0.009 16.0 12.6 2.6 1 1 0 1 1 1 1 Kazal-type serine protease inhibitor domain Ig_3 PF13927.1 KFM11877.1 - 0.0023 18.3 0.0 0.0047 17.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain IGFBP PF00219.13 KFM11877.1 - 0.0027 18.2 20.7 0.0027 18.2 14.3 2.1 2 0 0 2 2 2 1 Insulin-like growth factor binding protein Kazal_2 PF07648.10 KFM11877.1 - 0.0054 16.6 3.8 0.0054 16.6 2.6 2.2 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Neur_chan_LBD PF02931.18 KFM11878.1 - 3.3e-48 163.7 0.1 3.3e-48 163.7 0.1 1.5 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFM11878.1 - 3.8e-28 98.9 9.6 1.3e-25 90.6 3.3 2.1 1 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region EF-hand_7 PF13499.1 KFM11879.1 - 8.4e-25 86.6 4.2 5.4e-15 55.2 0.2 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KFM11879.1 - 9e-19 65.2 5.9 3.4e-07 29.0 0.1 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 KFM11879.1 - 1.6e-16 58.6 2.9 0.00019 21.0 0.0 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 KFM11879.1 - 1.5e-15 56.5 3.5 0.00026 20.5 0.0 4.2 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 KFM11879.1 - 7.5e-12 44.0 3.8 4.9e-05 22.4 0.0 3.5 4 0 0 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.4 KFM11879.1 - 1.6e-06 28.1 0.5 2.7e-05 24.1 0.1 2.7 1 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFM11879.1 - 0.0014 18.2 1.8 0.056 13.1 0.1 2.8 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KFM11879.1 - 0.004 17.0 0.2 6.8 6.6 0.0 3.8 3 1 0 3 3 3 1 EF-hand domain EF-hand_2 PF09068.6 KFM11879.1 - 0.0071 16.4 0.1 0.62 10.1 0.0 2.6 2 1 0 2 2 2 1 EF hand S10_plectin PF03501.10 KFM11879.1 - 0.011 15.5 0.1 0.024 14.5 0.1 1.6 1 1 0 1 1 1 0 Plectin/S10 domain EF-hand_10 PF14788.1 KFM11879.1 - 0.012 15.2 0.4 3.9 7.2 0.0 3.0 3 0 0 3 3 3 0 EF hand CaKB PF03185.10 KFM11880.1 - 8.2e-82 273.4 0.4 9.1e-82 273.3 0.3 1.0 1 0 0 1 1 1 1 Calcium-activated potassium channel, beta subunit Fork_head PF00250.13 KFM11881.1 - 8.9e-44 147.4 0.1 1.1e-43 147.2 0.1 1.0 1 0 0 1 1 1 1 Fork head domain DOCK-C2 PF14429.1 KFM11882.1 - 3.1e-50 170.3 0.0 1.1e-49 168.5 0.0 2.1 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 KFM11882.1 - 1.7e-41 141.5 0.5 5.7e-41 139.7 0.0 2.3 2 0 0 2 2 2 1 Dedicator of cytokinesis SH3_9 PF14604.1 KFM11882.1 - 6.7e-06 25.5 0.0 1.3e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM11882.1 - 8.9e-06 25.0 0.0 1.7e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFM11882.1 - 0.0008 18.8 0.1 0.0017 17.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain FAM196 PF15265.1 KFM11883.1 - 1.1e-172 575.8 24.8 1.2e-172 575.7 17.2 1.0 1 0 0 1 1 1 1 FAM196 family PspA_IM30 PF04012.7 KFM11884.1 - 0.0088 15.4 20.5 0.0088 15.4 14.2 4.8 3 2 2 5 5 5 3 PspA/IM30 family DUF1949 PF09186.6 KFM11884.1 - 0.14 11.7 1.6 0.34 10.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1949) LRR_8 PF13855.1 KFM11885.1 - 2.7e-86 283.2 72.3 1.8e-15 56.4 0.7 9.4 4 3 5 9 9 9 9 Leucine rich repeat LRR_4 PF12799.2 KFM11885.1 - 4.2e-43 144.3 57.6 1.3e-06 27.8 1.4 11.4 6 3 5 13 13 13 12 Leucine Rich repeats (2 copies) EGF PF00008.22 KFM11885.1 - 8.6e-30 102.3 99.9 1e-06 28.5 4.4 8.7 9 0 0 9 9 7 6 EGF-like domain LRR_1 PF00560.28 KFM11885.1 - 4.4e-24 80.8 49.3 0.29 11.3 0.0 18.6 20 0 0 20 20 20 10 Leucine Rich Repeat LRRNT PF01462.13 KFM11885.1 - 4.7e-19 67.3 44.2 7.4e-09 34.8 2.2 7.0 7 0 0 7 7 7 3 Leucine rich repeat N-terminal domain Laminin_G_2 PF02210.19 KFM11885.1 - 1.4e-18 67.2 0.1 2.2e-18 66.5 0.1 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.18 KFM11885.1 - 5.6e-15 55.5 0.1 8.9e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain LRR_9 PF14580.1 KFM11885.1 - 4.1e-13 49.2 21.4 0.0025 17.4 1.0 5.7 4 2 1 5 5 5 4 Leucine-rich repeat hEGF PF12661.2 KFM11885.1 - 2.5e-08 33.4 63.5 0.0014 18.5 1.6 9.1 8 0 0 8 8 6 5 Human growth factor-like EGF LRR_6 PF13516.1 KFM11885.1 - 9.2e-07 28.3 48.3 0.93 9.7 0.1 16.0 13 5 3 16 16 16 2 Leucine Rich repeat EGF_2 PF07974.8 KFM11885.1 - 0.013 15.6 13.0 0.013 15.6 9.0 10.4 13 0 0 13 13 9 0 EGF-like domain LRR_7 PF13504.1 KFM11885.1 - 0.024 14.7 54.1 8.4 7.0 0.0 15.0 18 0 0 18 18 14 0 Leucine rich repeat Laminin_G_3 PF13385.1 KFM11885.1 - 0.31 11.2 0.0 0.55 10.4 0.0 1.3 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Fumble PF03630.9 KFM11886.1 - 6.1e-145 482.3 0.0 6.8e-145 482.1 0.0 1.0 1 0 0 1 1 1 1 Fumble Imm11 PF15563.1 KFM11886.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 11 tRNA-synt_1d PF00750.14 KFM11887.1 - 2.4e-136 454.2 0.0 3.3e-136 453.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) Arg_tRNA_synt_N PF03485.11 KFM11887.1 - 1.3e-22 80.1 0.6 4.2e-22 78.4 0.1 2.2 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain DALR_1 PF05746.10 KFM11887.1 - 6.2e-21 74.5 0.2 1.6e-20 73.2 0.1 1.8 1 0 0 1 1 1 1 DALR anticodon binding domain tRNA-synt_1e PF01406.14 KFM11887.1 - 0.015 14.4 0.0 0.048 12.7 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Microtub_assoc PF07989.6 KFM11887.1 - 0.021 14.6 0.2 0.1 12.4 0.2 2.2 1 0 0 1 1 1 0 Microtubule associated Striatin PF08232.7 KFM11887.1 - 0.08 13.2 0.8 2.1 8.6 0.0 2.3 2 0 0 2 2 2 0 Striatin family tRNA-synt_1 PF00133.17 KFM11887.1 - 0.099 10.6 0.0 0.16 9.9 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) WW PF00397.21 KFM11888.1 - 1.2e-08 34.6 0.2 2.6e-08 33.5 0.2 1.6 1 0 0 1 1 1 1 WW domain Sec2p PF06428.6 KFM11888.1 - 0.0011 18.7 1.5 0.0011 18.7 1.0 5.1 6 1 0 6 6 6 1 GDP/GTP exchange factor Sec2p C2 PF00168.25 KFM11888.1 - 0.035 13.9 0.0 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 C2 domain Ten_N PF06484.7 KFM11889.1 - 1.3e-61 208.7 18.6 2.2e-61 208.0 12.9 1.4 1 0 0 1 1 1 1 Teneurin Intracellular Region Tox-GHH PF15636.1 KFM11889.1 - 8.2e-31 105.4 0.5 1.6e-30 104.5 0.4 1.5 1 0 0 1 1 1 1 GHH signature containing HNH/Endo VII superfamily nuclease toxin EGF_2 PF07974.8 KFM11889.1 - 1.9e-17 63.1 162.6 0.0014 18.7 9.7 9.6 9 0 0 9 9 9 8 EGF-like domain NHL PF01436.16 KFM11889.1 - 1.6e-12 46.7 2.9 0.0022 17.8 0.0 6.6 7 0 0 7 7 7 3 NHL repeat RHS_repeat PF05593.9 KFM11889.1 - 3e-11 43.1 35.8 0.00049 20.1 1.4 10.0 9 3 1 10 10 10 3 RHS Repeat hEGF PF12661.2 KFM11889.1 - 4e-07 29.6 76.0 0.084 12.9 1.6 9.3 8 0 0 8 8 8 7 Human growth factor-like EGF CarboxypepD_reg PF13620.1 KFM11889.1 - 3.9e-05 23.6 0.0 0.00018 21.4 0.0 2.2 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Ten_N PF06484.7 KFM11891.1 - 6.5e-33 114.3 3.4 7.2e-33 114.1 2.4 1.0 1 0 0 1 1 1 1 Teneurin Intracellular Region RVT_1 PF00078.22 KFM11892.1 - 0.048 13.0 0.0 0.065 12.5 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RmlD_sub_bind PF04321.12 KFM11893.1 - 5.8e-82 274.8 0.0 6.8e-82 274.5 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 KFM11893.1 - 2.1e-24 86.2 0.0 2.6e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KFM11893.1 - 4e-10 39.0 0.2 1.9e-07 30.2 0.1 2.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 KFM11893.1 - 6.8e-08 31.7 0.0 5.2e-05 22.2 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 KFM11893.1 - 5.2e-07 29.8 0.0 6.7e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KFM11893.1 - 0.00023 19.9 0.1 0.001 17.8 0.1 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KFM11893.1 - 0.0045 16.9 0.4 0.063 13.2 0.0 2.6 2 2 1 3 3 3 1 short chain dehydrogenase ATG16 PF08614.6 KFM11894.1 - 3.4 7.4 115.3 0.81 9.4 9.1 6.5 1 1 3 5 5 5 0 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 KFM11894.1 - 3.9 6.5 32.4 1.7 7.7 0.8 4.9 2 1 3 5 5 5 0 Reovirus sigma C capsid protein Cyclin_N PF00134.18 KFM11895.1 - 2.1e-21 75.8 0.1 4.6e-21 74.6 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFM11895.1 - 0.0085 16.0 4.8 0.018 14.9 1.6 2.4 2 1 1 3 3 3 1 Cyclin, C-terminal domain PX PF00787.19 KFM11895.1 - 0.093 12.5 0.7 0.21 11.4 0.5 1.6 1 0 0 1 1 1 0 PX domain Neur_chan_memb PF02932.11 KFM11897.1 - 2.2e-50 171.7 3.7 6.2e-45 153.9 0.3 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 KFM11897.1 - 2.4e-41 141.2 1.8 3.3e-41 140.8 1.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_LBD PF02931.18 KFM11898.1 - 1.4e-52 177.9 0.0 1.9e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFM11898.1 - 3.7e-45 154.6 5.6 1.4e-36 126.5 4.0 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_memb PF02932.11 KFM11899.1 - 5e-54 183.7 1.5 2.4e-53 181.4 1.1 1.9 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 KFM11899.1 - 9.6e-53 178.5 0.0 2.3e-52 177.3 0.0 1.6 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain E1-E2_ATPase PF00122.15 KFM11900.1 - 2.5e-14 52.8 0.0 6e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 KFM11900.1 - 1.6e-13 51.2 0.3 2.5e-12 47.3 0.2 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFM11900.1 - 2.2e-13 51.1 0.1 6.3e-09 36.5 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFM11900.1 - 1.1e-08 34.8 0.0 6e-08 32.5 0.0 2.2 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFM11900.1 - 0.0064 16.1 2.0 0.017 14.7 0.1 2.4 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Securin PF04856.8 KFM11901.1 - 6.4e-17 62.0 0.1 7.9e-17 61.7 0.1 1.1 1 0 0 1 1 1 1 Securin sister-chromatid separation inhibitor Slu7 PF11708.3 KFM11902.1 - 1.5e-87 293.3 12.2 1.5e-87 293.3 8.5 2.7 3 0 0 3 3 3 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 KFM11902.1 - 0.031 13.9 0.7 0.067 12.8 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle FmdE PF02663.9 KFM11902.1 - 1.1 9.1 5.0 2.9 7.7 2.0 2.6 2 0 0 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon C1q PF00386.16 KFM11903.1 - 4.6e-38 130.0 0.0 5.6e-38 129.8 0.0 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 KFM11903.1 - 1.2e-17 63.2 61.9 8.1e-10 38.1 23.9 2.3 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Cyclin_C PF02984.14 KFM11904.1 - 2.6e-26 91.8 5.5 1e-24 86.7 1.0 2.5 2 1 0 2 2 2 2 Cyclin, C-terminal domain Cyclin_N PF00134.18 KFM11904.1 - 3.5e-20 71.8 5.3 9.6e-20 70.4 0.8 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Methuselah_N PF06652.7 KFM11904.1 - 0.0012 18.4 0.1 0.0022 17.5 0.1 1.5 1 0 0 1 1 1 1 Methuselah N-terminus Lipocalin_7 PF14651.1 KFM11905.1 - 1e-60 203.0 1.1 1.1e-60 202.9 0.7 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin PF00061.18 KFM11905.1 - 8.3e-10 38.8 1.3 9.3e-10 38.6 0.9 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family DUF4166 PF13761.1 KFM11905.1 - 0.034 14.0 0.0 0.04 13.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4166) PWWP PF00855.12 KFM11907.1 - 2.1e-12 47.0 0.1 2.1e-12 47.0 0.0 2.8 2 1 0 2 2 2 1 PWWP domain DUF1018 PF06252.7 KFM11907.1 - 1.6 9.2 11.1 4.4 7.8 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1018) TPR_11 PF13414.1 KFM11908.1 - 7.9e-26 89.5 6.2 9e-18 63.6 0.2 2.3 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KFM11908.1 - 8e-24 82.2 3.0 5.9e-07 28.8 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFM11908.1 - 1.3e-16 59.1 3.5 8.2e-05 22.2 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFM11908.1 - 1.3e-09 37.8 2.2 6.6e-05 22.7 0.8 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFM11908.1 - 2.4e-09 36.3 5.9 0.0062 16.2 0.3 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFM11908.1 - 2.6e-07 31.1 0.6 9.8e-05 22.9 0.6 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFM11908.1 - 1.7e-05 24.5 3.3 4.2e-05 23.3 1.3 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFM11908.1 - 2.6e-05 24.4 5.7 0.00076 19.7 0.9 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFM11908.1 - 5.3e-05 23.4 1.2 0.18 12.5 0.3 3.3 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFM11908.1 - 8.8e-05 22.0 1.7 0.27 11.1 0.3 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 KFM11908.1 - 0.00013 21.1 3.7 0.025 13.6 0.4 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFM11908.1 - 0.00021 21.2 2.6 0.0015 18.5 0.1 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat RPN7 PF10602.4 KFM11908.1 - 0.0052 16.1 2.5 0.0052 16.1 1.7 2.3 2 0 0 2 2 2 1 26S proteasome subunit RPN7 TPR_6 PF13174.1 KFM11908.1 - 0.0083 16.5 4.0 0.06 13.8 0.3 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat PaaX_C PF08223.6 KFM11908.1 - 0.014 15.1 1.1 0.022 14.4 0.7 1.3 1 0 0 1 1 1 0 PaaX-like protein C-terminal domain DUF3856 PF12968.2 KFM11908.1 - 0.036 13.8 1.3 3.6 7.3 0.9 3.0 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) A2M_N PF01835.14 KFM11908.1 - 0.073 13.3 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 MG2 domain NYD-SP28_assoc PF14775.1 KFM11908.1 - 0.51 10.0 5.1 2.2 8.0 0.4 2.6 1 1 1 2 2 2 0 Sperm tail C-terminal domain FTCD_C PF04961.7 KFM11908.1 - 2.3 7.5 6.8 0.096 12.0 0.4 1.8 2 1 0 2 2 2 0 Formiminotransferase-cyclodeaminase 7tm_1 PF00001.16 KFM11909.1 - 5.6e-83 278.0 8.7 7.6e-83 277.5 6.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM11909.1 - 3.4e-16 59.1 4.8 7.7e-16 58.0 3.3 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM11909.1 - 0.00017 20.8 8.5 0.00049 19.2 5.9 1.7 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx IL12p40_C PF10420.4 KFM11911.1 - 1.3e-24 86.0 4.4 1.6e-24 85.8 0.9 2.6 3 1 0 4 4 4 1 Cytokine interleukin-12p40 C-terminus Ig_2 PF13895.1 KFM11911.1 - 0.00063 19.8 1.3 0.0059 16.7 0.0 2.8 1 1 2 3 3 3 1 Immunoglobulin domain Ig_3 PF13927.1 KFM11911.1 - 0.0021 18.5 3.2 0.046 14.2 0.0 3.0 3 0 0 3 3 3 1 Immunoglobulin domain GPI-anchored PF10342.4 KFM11911.1 - 0.17 12.3 2.6 11 6.6 0.3 3.2 3 1 0 3 3 3 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family F-box PF00646.28 KFM11912.1 - 9.8e-05 21.9 0.1 0.00029 20.3 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KFM11912.1 - 0.00093 18.8 0.3 0.0023 17.6 0.2 1.6 1 0 0 1 1 1 1 F-box-like Zip PF02535.17 KFM11912.1 - 9 5.2 5.4 20 4.0 3.7 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter 7tm_1 PF00001.16 KFM11913.1 - 1.1e-73 247.5 15.3 1.8e-73 246.8 10.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.3 KFM11913.1 - 0.43 10.1 15.2 1 8.9 10.5 1.6 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 Sulfate_transp PF00916.15 KFM11914.1 - 4.8e-79 265.2 8.5 1e-78 264.1 5.9 1.6 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KFM11914.1 - 1.6e-31 107.8 2.5 1.6e-31 107.8 1.7 3.3 5 0 0 5 5 5 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KFM11914.1 - 4.2e-29 100.3 0.0 7.3e-29 99.5 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 KFM11914.1 - 0.077 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 STAS domain zf-B_box PF00643.19 KFM11915.1 - 4e-08 33.0 5.3 4e-08 33.0 3.7 2.8 3 0 0 3 3 3 2 B-box zinc finger Carla_C4 PF01623.12 KFM11915.1 - 0.14 11.9 3.5 0.51 10.1 2.0 1.9 1 1 1 2 2 2 0 Carlavirus putative nucleic acid binding protein zf-B_box PF00643.19 KFM11916.1 - 4e-08 33.0 11.7 4e-08 33.0 8.1 3.7 4 1 0 4 4 4 2 B-box zinc finger RhoGEF PF00621.15 KFM11917.1 - 1.9e-37 128.8 0.4 4.3e-37 127.7 0.3 1.6 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.13 KFM11917.1 - 3.5e-24 85.5 3.8 5.8e-23 81.5 2.1 2.8 2 1 0 2 2 2 1 BAR domain SH3_2 PF07653.12 KFM11917.1 - 1.1e-13 50.3 0.0 3.7e-06 26.3 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.1 KFM11917.1 - 5.7e-12 45.0 0.0 5e-08 32.4 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KFM11917.1 - 1.6e-07 30.6 0.0 4.4e-06 25.9 0.0 2.6 2 0 0 2 2 2 1 SH3 domain SH3_3 PF08239.6 KFM11917.1 - 2e-05 24.6 0.1 0.00035 20.7 0.0 2.5 2 0 0 2 2 2 1 Bacterial SH3 domain UvrB PF12344.3 KFM11917.1 - 2.6 7.6 4.8 0.55 9.8 0.5 1.9 2 0 0 2 2 2 0 Ultra-violet resistance protein B Pkinase PF00069.20 KFM11918.1 - 1.8e-38 132.2 0.0 2.1e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM11918.1 - 8.8e-15 54.4 0.0 1e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFM11918.1 - 0.012 15.3 0.1 0.44 10.2 0.1 2.3 1 1 0 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KFM11918.1 - 0.012 14.4 0.1 0.019 13.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 KFM11918.1 - 0.038 12.9 0.0 0.08 11.8 0.0 1.5 2 0 0 2 2 2 0 Kinase-like IL17 PF06083.6 KFM11919.1 - 2e-30 104.6 1.4 3.5e-30 103.8 0.9 1.4 1 0 0 1 1 1 1 Interleukin-17 Prenylcys_lyase PF07156.9 KFM11920.1 - 1.2e-158 527.8 0.0 1.4e-158 527.6 0.0 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 KFM11920.1 - 2.1e-06 27.6 0.1 5.4e-06 26.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GrpE PF01025.14 KFM11921.1 - 1e-43 148.7 0.0 1.2e-43 148.5 0.0 1.0 1 0 0 1 1 1 1 GrpE Laminin_I PF06008.9 KFM11921.1 - 0.0093 15.3 0.1 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Laminin Domain I DUF2408 PF10303.4 KFM11921.1 - 0.03 14.4 0.2 0.043 13.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DUF4525 PF15027.1 KFM11921.1 - 0.063 12.8 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4525) PH PF00169.24 KFM11922.1 - 3.1e-18 65.8 0.0 1.3e-07 31.7 0.0 2.6 2 0 0 2 2 2 2 PH domain Macoilin PF09726.4 KFM11922.1 - 0.00021 19.7 5.5 0.00021 19.7 3.8 1.7 2 0 0 2 2 2 1 Transmembrane protein PH_11 PF15413.1 KFM11922.1 - 0.00066 19.9 2.3 0.14 12.4 0.0 3.6 3 1 0 3 3 3 2 Pleckstrin homology domain IncA PF04156.9 KFM11922.1 - 2.6 7.5 12.1 5.7 6.4 8.4 1.6 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 KFM11922.1 - 5.2 4.7 5.3 8.3 4.1 3.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LIM PF00412.17 KFM11923.1 - 1.2e-33 114.9 36.7 2.4e-14 53.1 2.8 4.7 4 1 1 5 5 5 4 LIM domain VHP PF02209.14 KFM11923.1 - 1.7e-17 62.8 0.8 3.6e-17 61.7 0.6 1.6 1 0 0 1 1 1 1 Villin headpiece domain TPR_12 PF13424.1 KFM11924.1 - 2e-17 62.8 41.7 6.9e-06 25.9 4.6 8.0 6 2 2 8 8 8 5 Tetratricopeptide repeat SH3_9 PF14604.1 KFM11924.1 - 5.8e-13 48.2 0.4 1.6e-08 34.0 0.0 2.8 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.12 KFM11924.1 - 2.6e-10 39.6 0.1 6.1e-05 22.4 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain TPR_11 PF13414.1 KFM11924.1 - 5.4e-10 38.7 30.0 0.0032 17.0 2.2 6.7 5 1 1 6 6 6 5 TPR repeat SH3_1 PF00018.23 KFM11924.1 - 4.6e-09 35.5 0.3 0.00081 18.7 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SNAP PF14938.1 KFM11924.1 - 3e-07 29.8 1.4 2.6e-05 23.5 0.2 3.3 3 0 0 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_1 PF00515.23 KFM11924.1 - 3.4e-06 26.4 31.1 0.00082 18.8 0.0 9.1 9 1 1 10 10 10 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFM11924.1 - 0.001 18.7 38.3 0.027 14.3 0.0 10.2 10 1 1 11 11 11 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFM11924.1 - 0.0025 17.4 21.5 4.6 7.2 0.0 9.5 13 0 0 13 13 11 2 Tetratricopeptide repeat ARA70 PF12489.3 KFM11924.1 - 0.027 14.4 0.7 0.09 12.7 0.5 1.9 1 0 0 1 1 1 0 Nuclear coactivator TPR_7 PF13176.1 KFM11924.1 - 1.3 9.0 18.0 27 4.8 0.1 8.1 8 1 1 9 9 9 0 Tetratricopeptide repeat ubiquitin PF00240.18 KFM11925.1 - 2.7e-09 36.2 0.0 4.2e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KFM11925.1 - 0.00051 19.6 0.0 0.00079 19.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Duffy_binding PF05424.6 KFM11925.1 - 0.089 12.6 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 Duffy binding domain SH3_1 PF00018.23 KFM11926.1 - 4.4e-40 134.8 14.7 1.2e-13 50.1 0.2 4.5 4 0 0 4 4 4 4 SH3 domain SH3_9 PF14604.1 KFM11926.1 - 7.2e-36 121.5 9.0 4.1e-13 48.6 0.1 4.6 4 0 0 4 4 4 4 Variant SH3 domain SH3_2 PF07653.12 KFM11926.1 - 2.1e-32 110.3 5.4 1.3e-09 37.4 0.0 4.3 4 0 0 4 4 4 4 Variant SH3 domain SH3_3 PF08239.6 KFM11926.1 - 3.9e-14 52.5 13.6 6.3e-05 23.0 0.4 4.4 4 0 0 4 4 4 4 Bacterial SH3 domain PX PF00787.19 KFM11926.1 - 6.2e-07 29.1 2.6 1.9e-06 27.6 0.0 2.5 2 0 0 2 2 2 1 PX domain SH3_4 PF06347.8 KFM11926.1 - 9.6e-05 21.8 16.5 0.0001 21.7 0.4 3.9 4 0 0 4 4 4 3 Bacterial SH3 domain Neuralized PF07177.7 KFM11927.1 - 6.8e-41 137.9 0.3 1.3e-24 85.7 0.1 2.5 2 0 0 2 2 2 2 Neuralized zf-C3HC4_3 PF13920.1 KFM11927.1 - 6.3e-13 48.1 13.2 1.4e-12 47.0 9.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM11927.1 - 2e-05 24.4 15.9 5.1e-05 23.2 11.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM11927.1 - 0.024 14.3 15.0 0.059 13.1 10.4 1.7 1 0 0 1 1 1 0 zinc-RING finger domain DSPc PF00782.15 KFM11929.1 - 3.5e-49 165.7 0.0 4.3e-49 165.4 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFM11929.1 - 2.4e-07 30.3 0.0 2.9e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KFM11929.1 - 0.002 18.1 0.0 0.0029 17.6 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.7 KFM11929.1 - 0.082 12.3 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) COPIIcoated_ERV PF07970.7 KFM11930.1 - 4.6e-38 131.0 0.1 7.9e-38 130.2 0.1 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KFM11930.1 - 6.9e-25 86.8 1.2 1.3e-24 86.0 0.0 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) KOW PF00467.24 KFM11931.1 - 4.3e-08 32.5 5.9 1.8e-07 30.6 4.1 2.2 1 1 0 1 1 1 1 KOW motif PilP PF04351.8 KFM11931.1 - 0.16 11.9 2.1 0.26 11.1 1.5 1.6 1 1 0 1 1 1 0 Pilus assembly protein, PilP Toxin_56 PF15534.1 KFM11931.1 - 0.49 10.9 5.7 0.21 12.0 0.6 2.2 2 1 0 2 2 2 0 Putative toxin 56 bZIP_1 PF00170.16 KFM11932.1 - 0.00057 19.7 3.4 0.00057 19.7 2.4 3.0 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.10 KFM11932.1 - 0.011 15.5 1.9 0.011 15.5 1.3 2.1 2 0 0 2 2 2 0 Basic region leucine zipper TFIIA PF03153.8 KFM11932.1 - 0.027 14.3 13.4 0.057 13.3 9.3 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2457 PF10446.4 KFM11932.1 - 0.4 9.3 19.6 0.71 8.5 13.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 KFM11932.1 - 3.4 5.4 19.9 5 4.9 13.8 1.2 1 0 0 1 1 1 0 Nop14-like family Sec20 PF03908.8 KFM11933.1 - 1.3e-33 114.5 2.2 2.6e-33 113.5 1.6 1.5 1 0 0 1 1 1 1 Sec20 DUF2777 PF10949.3 KFM11933.1 - 0.0022 17.6 1.3 0.003 17.2 0.5 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2777) Hormone_recep PF00104.25 KFM11933.1 - 0.019 14.0 0.1 0.093 11.8 0.1 1.9 1 1 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor WD-3 PF09765.4 KFM11933.1 - 0.24 10.6 2.5 0.29 10.3 1.7 1.1 1 0 0 1 1 1 0 WD-repeat region V-SNARE_C PF12352.3 KFM11933.1 - 0.35 10.9 5.2 0.31 11.1 2.6 1.7 1 1 1 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus DUF3807 PF12720.2 KFM11933.1 - 1.5 8.9 7.8 2.5 8.2 5.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3807) DUF3490 PF11995.3 KFM11933.1 - 1.8 8.0 6.0 1.9 8.0 3.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3490) Elongin_A PF06881.6 KFM11933.1 - 3.9 7.8 7.6 1.8 8.9 3.4 1.8 1 1 1 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF2924 PF11149.3 KFM11933.1 - 8.5 6.3 9.3 83 3.1 6.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2924) Homeobox PF00046.24 KFM11934.1 - 9.2e-21 73.2 4.2 9.2e-21 73.2 2.9 1.7 2 0 0 2 2 2 1 Homeobox domain Homez PF11569.3 KFM11934.1 - 0.089 11.8 0.3 0.19 10.8 0.2 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Stanniocalcin PF03298.8 KFM11935.1 - 2.1e-83 278.4 12.7 2.7e-83 278.1 8.8 1.0 1 0 0 1 1 1 1 Stanniocalcin family COMPASS-Shg1 PF05205.7 KFM11936.1 - 1e-13 51.5 0.0 1.2e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 RRM_1 PF00076.17 KFM11937.1 - 8.6e-13 47.7 0.0 9.2e-08 31.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM11937.1 - 1.9e-07 30.9 0.0 6.9e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcyon PF06387.6 KFM11938.1 - 3.5e-89 297.1 0.1 4e-89 296.9 0.0 1.0 1 0 0 1 1 1 1 D1 dopamine receptor-interacting protein (calcyon) Homeobox PF00046.24 KFM11939.1 - 1e-22 79.4 5.2 1.5e-22 78.9 3.6 1.2 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 KFM11939.1 - 0.16 11.0 0.8 0.48 9.5 0.1 1.9 1 1 1 2 2 2 0 Homeodomain leucine-zipper encoding, Homez 7tm_1 PF00001.16 KFM11940.1 - 5.2e-80 268.2 19.4 6.4e-80 267.9 13.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM11940.1 - 1.7e-09 37.2 17.9 2.9e-09 36.4 12.4 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM11940.1 - 2.2e-06 27.0 15.4 2.2e-06 27.0 10.7 2.5 2 2 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Mtc PF03820.12 KFM11941.1 - 4.3e-149 495.2 0.1 5e-149 495.0 0.1 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Kinesin PF00225.18 KFM11942.1 - 1.6e-100 336.1 0.2 1.6e-100 336.1 0.2 1.8 2 0 0 2 2 2 1 Kinesin motor domain DUF2422 PF10337.4 KFM11942.1 - 0.15 10.7 9.4 0.28 9.9 6.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) DNA_topoisoIV PF00521.15 KFM11942.1 - 8.3 5.1 13.0 18 4.0 9.0 1.5 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Ribosomal_L7Ae PF01248.21 KFM11943.1 - 1.1e-20 72.9 0.0 1.2e-20 72.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Glyco_transf_7C PF02709.9 KFM11944.1 - 2.3e-27 94.2 0.2 4.7e-27 93.2 0.2 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.1 KFM11944.1 - 1.3e-23 82.8 0.0 2e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_tranf_2_2 PF10111.4 KFM11944.1 - 1.6e-05 24.1 0.0 0.011 14.8 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Lectin_leg-like PF03388.8 KFM11945.1 - 1.2e-73 247.0 0.0 1.5e-73 246.7 0.0 1.0 1 0 0 1 1 1 1 Legume-like lectin family Arf PF00025.16 KFM11946.1 - 2.9e-67 225.2 0.0 3.2e-67 225.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KFM11946.1 - 2.7e-13 49.6 0.0 3.2e-13 49.4 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KFM11946.1 - 4.7e-13 48.7 0.0 5.5e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KFM11946.1 - 2.8e-12 47.1 0.0 3.8e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 KFM11946.1 - 2.8e-10 39.7 0.0 3.3e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFM11946.1 - 2.2e-09 37.2 0.0 3e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 KFM11946.1 - 9.9e-09 34.3 0.1 2.5e-05 23.1 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit GTP_EFTU PF00009.22 KFM11946.1 - 2.3e-07 30.4 0.0 1.7e-05 24.3 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 KFM11946.1 - 0.0024 17.3 0.0 0.0048 16.3 0.0 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 KFM11946.1 - 0.014 15.5 0.0 0.11 12.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KFM11946.1 - 0.018 15.0 0.1 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KFM11946.1 - 0.023 15.0 0.2 0.044 14.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 KFM11946.1 - 0.032 13.5 0.0 0.076 12.2 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B cobW PF02492.14 KFM11946.1 - 0.037 13.4 0.0 2.9 7.2 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 KFM11946.1 - 0.048 13.5 0.0 0.11 12.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KFM11946.1 - 0.068 12.8 0.0 4.9 6.7 0.0 2.2 2 0 0 2 2 2 0 NACHT domain MobB PF03205.9 KFM11946.1 - 0.078 12.6 0.1 0.58 9.8 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 KFM11946.1 - 0.079 13.7 0.0 0.13 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KFM11946.1 - 0.08 12.6 0.0 0.14 11.8 0.0 1.3 1 1 0 1 1 1 0 NTPase Arch_ATPase PF01637.13 KFM11946.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase RBD PF02196.10 KFM11947.1 - 1e-31 108.4 0.2 8e-23 79.9 0.0 2.3 2 0 0 2 2 2 2 Raf-like Ras-binding domain RGS PF00615.14 KFM11947.1 - 1e-27 96.5 2.3 2.1e-27 95.5 1.6 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain GoLoco PF02188.12 KFM11947.1 - 5.5e-08 31.9 0.4 1.2e-07 30.8 0.3 1.6 1 0 0 1 1 1 1 GoLoco motif Bclx_interact PF08945.5 KFM11947.1 - 0.096 12.2 0.0 0.26 10.8 0.0 1.7 1 0 0 1 1 1 0 Bcl-x interacting, BH3 domain 7tm_1 PF00001.16 KFM11948.1 - 2.1e-69 233.5 7.0 2.4e-69 233.3 4.9 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM11948.1 - 2.7e-07 30.0 3.5 0.0043 16.2 0.1 2.4 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx Pkinase PF00069.20 KFM11949.1 - 5.3e-63 212.5 0.0 9.2e-63 211.8 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM11949.1 - 2.4e-35 121.8 0.0 3.8e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.14 KFM11949.1 - 4.7e-20 71.8 0.3 1.8e-19 69.9 0.0 2.1 2 0 0 2 2 2 1 Regulator of G protein signaling domain Kinase-like PF14531.1 KFM11949.1 - 0.00015 20.7 0.0 0.00026 20.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DUF2370 PF10176.4 KFM11950.1 - 1.8 7.8 4.5 13 5.0 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2370) Cofilin_ADF PF00241.15 KFM11951.1 - 4.6e-14 52.3 0.0 1.1e-13 51.1 0.0 1.7 2 0 0 2 2 2 1 Cofilin/tropomyosin-type actin-binding protein LIM PF00412.17 KFM11952.1 - 1.4e-41 140.3 34.1 2.7e-15 56.1 4.5 3.4 3 0 0 3 3 3 3 LIM domain PDZ PF00595.19 KFM11952.1 - 5.2e-13 48.9 0.0 9.8e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM11952.1 - 0.001 18.9 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 PDZ domain IRS PF02174.12 KFM11953.1 - 2.1e-24 85.0 0.0 3.3e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 PTB domain (IRS-1 type) DEAD PF00270.24 KFM11954.1 - 4e-42 143.5 0.0 3.4e-40 137.3 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFM11954.1 - 1.2e-28 98.8 0.0 9.3e-28 95.9 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 KFM11954.1 - 0.0034 17.3 0.0 0.041 13.8 0.0 2.3 2 0 0 2 2 2 1 Helicase C-terminal domain zf-CCHC PF00098.18 KFM11954.1 - 0.008 16.0 2.0 0.015 15.1 1.4 1.5 1 0 0 1 1 1 1 Zinc knuckle SecA_DEAD PF07517.9 KFM11954.1 - 0.018 14.3 0.0 0.036 13.3 0.0 1.5 1 0 0 1 1 1 0 SecA DEAD-like domain DUF1253 PF06862.7 KFM11954.1 - 0.018 13.4 0.0 0.13 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) Helicase_C_4 PF13871.1 KFM11954.1 - 0.037 13.4 0.0 0.091 12.1 0.0 1.6 1 0 0 1 1 1 0 Helicase_C-like zf-CCHC_4 PF14392.1 KFM11954.1 - 0.22 11.2 1.3 0.47 10.1 0.9 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF3886 PF13025.1 KFM11954.1 - 3.5 7.6 16.7 7.7 6.5 2.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) NARP1 PF12569.3 KFM11955.1 - 0.1 11.3 5.6 0.15 10.7 3.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 AAA_32 PF13654.1 KFM11955.1 - 0.31 9.6 4.6 0.42 9.2 3.2 1.1 1 0 0 1 1 1 0 AAA domain DUF1669 PF07894.7 KFM11955.1 - 0.44 9.6 1.3 0.9 8.6 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1669) PRELI PF04707.9 KFM11957.1 - 2.8e-39 134.2 0.2 4e-39 133.7 0.2 1.2 1 0 0 1 1 1 1 PRELI-like family Ras PF00071.17 KFM11958.1 - 3.3e-14 52.6 0.0 4.6e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM11958.1 - 0.0047 17.4 0.0 0.29 11.6 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Cofilin_ADF PF00241.15 KFM11958.1 - 0.058 13.2 0.1 0.071 12.9 0.1 1.2 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein SET PF00856.23 KFM11960.1 - 3.2e-25 89.3 3.1 6.7e-25 88.2 0.7 2.5 2 1 0 2 2 2 1 SET domain PHD PF00628.24 KFM11960.1 - 9.2e-19 66.8 70.4 1.1e-07 31.4 7.6 6.8 4 2 2 6 6 6 4 PHD-finger PWWP PF00855.12 KFM11960.1 - 3.6e-16 59.1 0.4 3.6e-16 59.1 0.2 1.9 2 0 0 2 2 2 1 PWWP domain PHD_2 PF13831.1 KFM11960.1 - 3.5e-07 29.4 38.6 0.00056 19.1 1.4 6.2 5 1 0 5 5 5 4 PHD-finger zf-met PF12874.2 KFM11962.1 - 7.1e-15 54.6 14.9 1.3e-07 31.5 0.4 3.3 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFM11962.1 - 2.1e-09 37.2 7.2 0.0003 20.8 1.2 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.7 KFM11962.1 - 0.0013 18.2 7.9 0.12 11.9 1.0 3.3 3 0 0 3 3 3 2 U1 zinc finger zf-C2H2_2 PF12756.2 KFM11962.1 - 0.0014 18.7 7.9 0.12 12.4 0.5 2.3 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C3HC4_2 PF13923.1 KFM11962.1 - 0.0076 16.2 0.2 2.4 8.2 0.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_4 PF13894.1 KFM11962.1 - 0.029 14.7 10.5 0.092 13.1 0.5 2.8 3 0 0 3 3 2 0 C2H2-type zinc finger Vps39_2 PF10367.4 KFM11962.1 - 0.033 14.3 1.2 2.8 8.1 0.0 2.3 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 HoxA13_N PF12284.3 KFM11962.1 - 0.12 12.5 1.8 0.91 9.6 0.1 2.3 1 1 0 2 2 2 0 Hox protein A13 N terminal DUF2946 PF11162.3 KFM11962.1 - 0.21 11.8 4.7 0.63 10.2 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2946) DUF2225 PF09986.4 KFM11962.1 - 0.33 10.3 2.1 0.92 8.9 0.2 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF2256 PF10013.4 KFM11962.1 - 0.36 10.6 3.0 13 5.6 0.4 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_6 PF13912.1 KFM11962.1 - 0.43 10.5 8.3 3.4 7.7 1.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFM11962.1 - 0.6 10.5 0.1 0.6 10.5 0.1 3.5 4 1 0 4 4 2 0 Zinc-finger double domain zf-C2H2 PF00096.21 KFM11962.1 - 1.1 9.7 10.5 0.51 10.7 0.6 3.0 2 1 1 3 3 3 0 Zinc finger, C2H2 type zf-RING_3 PF14369.1 KFM11962.1 - 1.5 8.9 4.2 11 6.0 0.5 2.3 2 0 0 2 2 2 0 zinc-finger UIM PF02809.15 KFM11963.1 - 0.0089 15.5 3.0 0.0089 15.5 2.1 3.2 3 0 0 3 3 3 2 Ubiquitin interaction motif Carboxyl_trans PF01039.17 KFM11963.1 - 0.53 8.5 2.6 0.22 9.8 0.0 1.6 2 0 0 2 2 2 0 Carboxyl transferase domain Hexokinase_2 PF03727.11 KFM11964.1 - 3e-172 570.1 1.3 5.9e-99 330.1 0.1 2.2 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 KFM11964.1 - 4e-139 460.6 0.0 3.2e-75 251.9 0.0 2.3 2 0 0 2 2 2 2 Hexokinase NdhO PF11910.3 KFM11964.1 - 0.033 13.8 0.0 2.2 7.9 0.0 3.1 2 1 1 3 3 3 0 Cyanobacterial and plant NDH-1 subunit O IF4E PF01652.13 KFM11965.1 - 8.8e-57 191.2 1.4 1e-56 191.0 1.0 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Synuclein PF01387.12 KFM11966.1 - 2.4e-17 63.0 2.7 3.7e-17 62.4 1.9 1.3 1 1 0 1 1 1 1 Synuclein ELFV_dehydrog PF00208.16 KFM11967.1 - 3.6e-51 174.0 0.0 7.4e-50 169.8 0.0 2.0 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 KFM11967.1 - 3.1e-30 104.4 0.0 5.7e-30 103.5 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Cadherin PF00028.12 KFM11969.1 - 1.6e-99 326.3 12.2 3.6e-15 55.9 0.1 9.5 9 0 0 9 9 9 9 Cadherin domain Cadherin_2 PF08266.7 KFM11969.1 - 1.2e-09 37.5 0.0 0.054 13.0 0.0 5.1 5 0 0 5 5 5 3 Cadherin-like DUF2208 PF09973.4 KFM11969.1 - 0.012 14.8 0.3 0.023 13.9 0.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) PepSY PF03413.14 KFM11969.1 - 0.034 14.7 0.2 7.5 7.2 0.0 4.0 4 0 0 4 4 4 0 Peptidase propeptide and YPEB domain UBA_4 PF14555.1 KFM11970.1 - 7.8e-08 31.7 0.3 4.4e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 UBA-like domain UBX PF00789.15 KFM11970.1 - 9.4e-07 28.8 0.1 3.6e-06 26.9 0.0 2.0 1 0 0 1 1 1 1 UBX domain UBA PF00627.26 KFM11970.1 - 0.00067 19.4 0.0 0.0017 18.1 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain NARP1 PF12569.3 KFM11970.1 - 0.035 12.8 10.2 0.054 12.2 7.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 AAA_23 PF13476.1 KFM11970.1 - 0.75 10.0 8.9 1.4 9.2 6.1 1.4 1 0 0 1 1 1 0 AAA domain DUF1682 PF07946.9 KFM11970.1 - 0.88 8.3 21.6 1.3 7.7 15.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF1510 PF07423.6 KFM11970.1 - 1.2 8.4 11.1 1.9 7.8 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Selenoprotein_S PF06936.6 KFM11970.1 - 1.4 8.4 9.8 2.2 7.7 6.8 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) Caldesmon PF02029.10 KFM11970.1 - 2.6 6.3 22.2 3.5 5.9 15.4 1.1 1 0 0 1 1 1 0 Caldesmon Clathrin_lg_ch PF01086.12 KFM11971.1 - 9.8e-55 185.9 9.8 1.1e-54 185.7 6.8 1.0 1 0 0 1 1 1 1 Clathrin light chain GED PF02212.13 KFM11971.1 - 0.066 13.1 1.1 0.14 12.0 0.7 1.5 1 0 0 1 1 1 0 Dynamin GTPase effector domain Glyco_hydro_65m PF03632.10 KFM11971.1 - 0.076 11.6 2.6 0.093 11.3 1.8 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65 central catalytic domain G6PD_N PF00479.17 KFM11971.1 - 0.87 9.7 3.8 17 5.6 0.0 2.2 1 1 1 2 2 2 0 Glucose-6-phosphate dehydrogenase, NAD binding domain CENP-Q PF13094.1 KFM11971.1 - 6.8 6.6 9.7 8.1 6.4 6.6 1.3 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit HIG_1_N PF04588.8 KFM11972.1 - 1.1e-19 69.8 1.9 1.3e-19 69.6 1.3 1.1 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Nop16 PF09420.5 KFM11973.1 - 2.5e-16 60.2 1.9 3e-16 59.9 1.3 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 ORF6C PF10552.4 KFM11973.1 - 2.3e-05 24.0 1.3 2.7e-05 23.8 0.9 1.2 1 0 0 1 1 1 1 ORF6C domain Arf PF00025.16 KFM11974.1 - 1.1e-39 135.4 0.0 1.5e-39 135.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 KFM11974.1 - 1.1e-09 38.7 0.0 1.7e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 KFM11974.1 - 2.4e-09 36.6 0.0 2.7e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KFM11974.1 - 3.1e-07 29.7 0.0 4.1e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 KFM11974.1 - 2.8e-06 26.8 0.0 3.3e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Ras family NACHT PF05729.7 KFM11974.1 - 0.0001 22.0 0.2 0.0082 15.8 0.1 2.3 1 1 0 1 1 1 1 NACHT domain G-alpha PF00503.15 KFM11974.1 - 0.00019 20.2 0.0 0.0012 17.6 0.0 1.9 1 1 1 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.22 KFM11974.1 - 0.00049 19.5 0.0 0.0019 17.6 0.0 1.8 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFM11974.1 - 0.00049 20.0 0.0 0.0017 18.3 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KFM11974.1 - 0.012 15.5 5.8 0.28 11.1 0.0 2.4 2 1 1 3 3 3 0 AAA ATPase domain AAA_22 PF13401.1 KFM11974.1 - 0.028 14.5 0.1 0.17 11.9 0.1 2.2 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KFM11974.1 - 0.12 12.6 0.0 0.13 12.5 0.0 1.5 1 1 0 1 1 1 0 ABC transporter cobW PF02492.14 KFM11974.1 - 0.13 11.6 0.0 3.5 7.0 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain P33MONOX PF15302.1 KFM11975.1 - 3e-120 401.2 9.9 3.4e-120 401.1 6.8 1.0 1 0 0 1 1 1 1 P33 mono-oxygenase Synaphin PF05835.7 KFM11976.1 - 8.7e-45 152.2 18.8 9.6e-45 152.1 13.0 1.0 1 0 0 1 1 1 1 Synaphin protein FCP1_C PF09309.5 KFM11976.1 - 0.23 10.7 10.7 0.28 10.4 7.4 1.2 1 0 0 1 1 1 0 FCP1, C-terminal DDRGK PF09756.4 KFM11976.1 - 0.47 9.8 17.6 0.62 9.4 12.2 1.2 1 0 0 1 1 1 0 DDRGK domain TEX19 PF15553.1 KFM11976.1 - 1.1 9.0 5.4 1.4 8.7 3.7 1.1 1 0 0 1 1 1 0 Testis-expressed protein 19 BSP_II PF05432.6 KFM11976.1 - 2.4 7.3 13.8 2.9 7.0 9.6 1.0 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF2570 PF10828.3 KFM11976.1 - 2.4 7.7 8.1 3.3 7.3 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Borrelia_P83 PF05262.6 KFM11976.1 - 2.4 6.3 14.1 2.6 6.2 9.8 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein VIT1 PF01988.14 KFM11976.1 - 3.4 7.1 5.9 4.3 6.7 4.1 1.3 1 0 0 1 1 1 0 VIT family DUF4407 PF14362.1 KFM11976.1 - 4.5 6.1 10.5 5.7 5.7 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6 PF04111.7 KFM11976.1 - 4.9 6.0 12.2 6.2 5.7 8.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 CAF-1_p150 PF11600.3 KFM11976.1 - 5.6 6.2 27.9 8 5.7 19.3 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CDC45 PF02724.9 KFM11976.1 - 7.3 4.5 9.7 8.8 4.2 6.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Ycf1 PF05758.7 KFM11976.1 - 8.6 3.9 9.2 8.5 3.9 6.4 1.0 1 0 0 1 1 1 0 Ycf1 IncA PF04156.9 KFM11976.1 - 8.6 5.9 7.9 11 5.6 5.5 1.3 1 0 0 1 1 1 0 IncA protein 7tm_1 PF00001.16 KFM11977.1 - 1.9e-71 240.2 19.4 2.3e-71 239.9 13.5 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM11977.1 - 4.4e-13 48.9 15.6 5.3e-13 48.7 10.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM11977.1 - 0.00041 19.5 15.6 0.00041 19.5 10.8 1.5 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Kazal_1 PF00050.16 KFM11978.1 - 5.6e-11 42.2 2.4 5.8e-11 42.2 1.7 1.0 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 KFM11978.1 - 4.9e-09 35.9 0.9 6.4e-09 35.5 0.6 1.2 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 KFM11979.1 - 1.6e-105 344.9 62.4 4.9e-18 64.8 3.6 6.1 6 0 0 6 6 6 6 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 KFM11979.1 - 6.3e-62 205.2 57.1 1.6e-11 43.9 2.3 6.3 6 0 0 6 6 6 6 Kazal-type serine protease inhibitor domain Avirulence PF03377.8 KFM11979.1 - 0.0085 14.8 0.0 0.014 14.1 0.0 1.4 1 1 0 1 1 1 1 Xanthomonas avirulence protein, Avr/PthA Kazal_1 PF00050.16 KFM11980.1 - 1.7e-50 168.7 29.7 1.5e-18 66.5 3.9 3.1 3 0 0 3 3 3 3 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 KFM11980.1 - 4.1e-35 119.4 23.4 2.1e-13 49.9 1.9 3.5 3 0 0 3 3 3 3 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 KFM11981.1 - 1.7e-11 43.9 4.3 2.6e-11 43.3 3.0 1.2 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 KFM11981.1 - 4.7e-08 32.8 3.0 6.9e-08 32.2 2.0 1.3 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 KFM11982.1 - 1.6e-16 60.0 4.1 1.8e-16 59.8 2.9 1.1 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 KFM11982.1 - 7.4e-15 54.5 2.2 9.9e-15 54.2 1.5 1.2 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain NIF PF03031.13 KFM11983.1 - 3.1e-29 101.6 0.2 5e-29 101.0 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.18 KFM11983.1 - 1.6e-06 27.4 0.1 3.4e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 KFM11983.1 - 0.014 15.6 0.1 0.037 14.2 0.1 1.8 1 0 0 1 1 1 0 Ubiquitin-like domain TRC8_N PF13705.1 KFM11984.1 - 3.2e-181 603.3 43.8 3.7e-181 603.1 30.4 1.0 1 0 0 1 1 1 1 TRC8 N-terminal domain zf-RING_2 PF13639.1 KFM11984.1 - 1.1e-11 44.3 7.6 1.1e-11 44.3 5.2 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFM11984.1 - 4.2e-08 33.0 6.5 4.2e-08 33.0 4.5 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFM11984.1 - 1e-07 31.9 7.4 3.1e-07 30.3 5.1 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KFM11984.1 - 2.4e-06 27.1 8.4 2.4e-06 27.1 5.8 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM11984.1 - 3.5e-06 26.5 6.5 3.5e-06 26.5 4.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM11984.1 - 0.00033 20.3 10.1 0.00033 20.3 7.0 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 KFM11984.1 - 0.013 15.3 7.0 0.033 14.0 4.9 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 KFM11984.1 - 0.09 12.3 6.5 0.21 11.1 4.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 NHase_alpha PF02979.11 KFM11984.1 - 0.15 11.3 0.1 0.33 10.2 0.1 1.5 1 0 0 1 1 1 0 Nitrile hydratase, alpha chain zf-RING_UBOX PF13445.1 KFM11984.1 - 0.96 9.2 10.7 0.029 14.1 1.9 2.7 3 1 1 4 4 4 0 RING-type zinc-finger zf-P11 PF03854.9 KFM11984.1 - 7.5 6.1 13.6 0.66 9.4 5.4 2.2 2 0 0 2 2 2 0 P-11 zinc finger TIG PF01833.19 KFM11985.1 - 7.4e-13 48.2 0.2 7.4e-13 48.2 0.2 2.8 2 0 0 2 2 2 1 IPT/TIG domain HLH PF00010.21 KFM11985.1 - 0.096 12.3 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain ENTH PF01417.15 KFM11986.1 - 7.6e-46 155.0 0.3 1.8e-45 153.8 0.0 1.7 2 0 0 2 2 2 1 ENTH domain ANTH PF07651.11 KFM11986.1 - 1.5e-05 23.8 0.0 2.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 ANTH domain LSM PF01423.17 KFM11987.1 - 5.7e-12 45.0 0.0 2e-06 27.2 0.0 2.2 2 0 0 2 2 2 2 LSM domain Thg1C PF14413.1 KFM11988.1 - 4.6e-51 171.5 0.6 7.1e-51 170.9 0.4 1.3 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 KFM11988.1 - 4.8e-33 113.6 0.2 6.8e-33 113.1 0.2 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase HMG_box PF00505.14 KFM11989.1 - 1e-22 80.1 1.3 1.7e-22 79.4 0.9 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFM11989.1 - 5.6e-11 42.6 0.3 9e-11 41.9 0.2 1.3 1 0 0 1 1 1 1 HMG-box domain Reprolysin PF01421.14 KFM11990.1 - 1.4e-63 214.1 0.0 1.4e-63 214.1 0.0 1.7 2 0 0 2 2 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.7 KFM11990.1 - 7.3e-33 113.1 6.3 7.3e-33 113.1 4.4 3.3 3 1 1 4 4 1 1 ADAM cysteine-rich Pep_M12B_propep PF01562.14 KFM11990.1 - 2.7e-30 104.8 0.2 4.4e-30 104.1 0.1 1.3 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_5 PF13688.1 KFM11990.1 - 9.6e-25 87.6 1.0 2.5e-24 86.3 0.7 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 Disintegrin PF00200.18 KFM11990.1 - 4.9e-24 84.3 26.1 4.9e-24 84.3 18.1 4.4 3 2 0 3 3 1 1 Disintegrin Reprolysin_3 PF13582.1 KFM11990.1 - 2.2e-19 70.2 0.1 6.8e-19 68.6 0.1 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFM11990.1 - 2.6e-15 56.9 2.0 2.7e-15 56.8 0.2 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFM11990.1 - 3.4e-14 52.8 0.2 6.6e-14 51.9 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like EGF_2 PF07974.8 KFM11990.1 - 0.0012 18.9 14.4 0.0012 18.9 10.0 5.9 5 1 0 5 5 1 1 EGF-like domain Peptidase_M66 PF10462.4 KFM11990.1 - 0.028 13.2 0.2 0.045 12.6 0.2 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M43 PF05572.8 KFM11990.1 - 0.036 13.6 0.2 0.09 12.3 0.1 1.6 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Peptidase_M10 PF00413.19 KFM11990.1 - 0.079 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Matrixin Mg_trans_NIPA PF05653.9 KFM11991.1 - 1.3e-130 434.7 13.8 1.6e-130 434.4 9.6 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 KFM11991.1 - 2e-09 37.6 0.7 2e-09 37.6 0.5 3.4 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KFM11991.1 - 6.9e-07 29.3 5.0 6.9e-07 29.3 3.4 3.6 3 1 1 4 4 4 1 EamA-like transporter family K1 PF02960.9 KFM11991.1 - 2 8.4 9.1 0.54 10.3 2.0 2.6 1 1 1 3 3 3 0 K1 glycoprotein Neur_chan_memb PF02932.11 KFM11991.1 - 7 6.4 6.7 13 5.5 4.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region fn3 PF00041.16 KFM11992.1 - 2.3e-05 24.4 0.2 3.4e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Fibronectin type III domain Ctr PF04145.10 KFM11992.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Ctr copper transporter family Pkinase_Tyr PF07714.12 KFM11993.1 - 7.7e-92 307.0 0.0 1.1e-91 306.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM11993.1 - 2.5e-50 171.0 0.0 4.3e-50 170.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 KFM11993.1 - 6.8e-21 73.8 0.0 1.4e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.23 KFM11993.1 - 1.7e-15 56.1 0.3 3.6e-15 55.0 0.2 1.6 1 0 0 1 1 1 1 SH3 domain BTK PF00779.14 KFM11993.1 - 1.3e-13 50.2 3.2 2.5e-13 49.3 2.2 1.5 1 0 0 1 1 1 1 BTK motif SH3_9 PF14604.1 KFM11993.1 - 4.9e-13 48.4 0.2 1.1e-12 47.3 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 KFM11993.1 - 9.8e-11 41.7 0.7 2.4e-10 40.5 0.5 1.7 1 0 0 1 1 1 1 PH domain SH3_2 PF07653.12 KFM11993.1 - 1.5e-08 33.9 0.0 3.3e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 KFM11993.1 - 0.0001 22.3 0.1 0.00028 21.0 0.1 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain PH_8 PF15409.1 KFM11993.1 - 0.0018 18.2 0.3 0.0071 16.3 0.2 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.1 KFM11993.1 - 0.018 14.0 0.0 0.037 12.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Med7 PF05983.6 KFM11994.1 - 9e-49 165.3 4.4 1.1e-48 165.0 3.0 1.1 1 0 0 1 1 1 1 MED7 protein Katanin_con80 PF13925.1 KFM11994.1 - 0.0025 17.5 1.0 0.0037 17.0 0.7 1.1 1 0 0 1 1 1 1 con80 domain of Katanin V-set PF07686.12 KFM11995.1 - 1.7e-14 53.6 2.1 2.3e-14 53.2 0.6 1.7 1 1 1 2 2 2 1 Immunoglobulin V-set domain I-set PF07679.11 KFM11995.1 - 0.00031 20.5 0.2 0.00069 19.4 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM11995.1 - 0.0023 18.0 2.3 0.0036 17.3 0.7 2.0 1 1 1 2 2 2 1 Immunoglobulin domain ig PF00047.20 KFM11995.1 - 0.017 15.2 4.0 0.035 14.2 0.3 3.0 1 1 1 2 2 2 0 Immunoglobulin domain Herpes_gI PF01688.12 KFM11995.1 - 0.057 12.5 0.0 0.14 11.3 0.0 1.7 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein I Herpes_capsid PF06112.6 KFM11995.1 - 0.61 10.1 4.6 0.89 9.5 3.2 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein V-set PF07686.12 KFM11996.1 - 1.4e-14 53.9 0.1 2.7e-14 53.0 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin V-set domain DUF4448 PF14610.1 KFM11996.1 - 0.0015 18.0 0.1 0.003 17.0 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) I-set PF07679.11 KFM11996.1 - 0.005 16.6 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 KFM11996.1 - 0.006 16.6 0.0 0.029 14.4 0.1 2.1 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.1 KFM11996.1 - 0.0079 16.2 0.3 0.023 14.7 0.1 1.9 2 0 0 2 2 2 1 Immunoglobulin domain Herpes_gE PF02480.11 KFM11996.1 - 0.0089 14.3 0.1 2.4 6.2 0.0 2.1 2 0 0 2 2 2 2 Alphaherpesvirus glycoprotein E Receptor_2B4 PF11465.3 KFM11996.1 - 0.019 14.8 0.0 0.076 12.9 0.0 2.0 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 TMEM154 PF15102.1 KFM11996.1 - 0.037 13.7 0.4 0.54 9.9 0.0 2.2 2 0 0 2 2 2 0 TMEM154 protein family Rifin_STEVOR PF02009.11 KFM11996.1 - 0.28 10.7 0.8 0.31 10.6 0.0 1.4 2 0 0 2 2 2 0 Rifin/stevor family Sarcoglycan_1 PF04790.8 KFM11997.1 - 1.4e-103 345.7 0.0 1.5e-103 345.5 0.0 1.0 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein DUF2345 PF10106.4 KFM11997.1 - 0.00084 18.9 0.0 0.0066 16.0 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2345) Ribosomal_L22 PF00237.14 KFM11998.1 - 5.2e-22 77.7 0.4 7.7e-22 77.2 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e WD40 PF00400.27 KFM11999.1 - 4.1e-46 153.2 36.6 2.8e-10 39.6 0.0 12.7 13 0 0 13 13 13 11 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KFM11999.1 - 0.00094 18.6 0.0 8.7 5.9 0.0 4.9 6 0 0 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain CAF1 PF04857.15 KFM12000.1 - 2.8e-71 239.9 0.2 4.2e-71 239.3 0.1 1.3 1 0 0 1 1 1 1 CAF1 family ribonuclease FA_hydroxylase PF04116.8 KFM12001.1 - 4.9e-14 52.6 18.7 4.9e-14 52.6 13.0 2.6 3 1 0 3 3 3 1 Fatty acid hydroxylase superfamily HLH PF00010.21 KFM12002.1 - 7.9e-17 60.6 0.1 1.4e-16 59.9 0.1 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain NicO PF03824.11 KFM12002.1 - 1.9 7.6 6.8 2.7 7.2 4.7 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein SAP30_Sin3_bdg PF13867.1 KFM12003.1 - 1.7e-25 88.6 0.2 4.1e-25 87.4 0.1 1.6 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 zf-SAP30 PF13866.1 KFM12003.1 - 7.9e-10 38.2 0.5 1.8e-09 37.1 0.3 1.6 1 0 0 1 1 1 1 SAP30 zinc-finger V-set PF07686.12 KFM12004.1 - 1.2e-07 31.5 0.1 7.9e-07 28.9 0.1 2.1 1 1 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 KFM12004.1 - 1.4e-07 31.2 0.0 2.8e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM12004.1 - 6.1e-05 23.0 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFM12004.1 - 0.023 15.2 0.0 0.083 13.4 0.0 2.1 1 0 0 1 1 1 0 Immunoglobulin domain Corona_3 PF04694.7 KFM12004.1 - 0.073 12.9 0.2 0.29 11.0 0.1 2.0 1 1 1 2 2 2 0 Coronavirus ORF3 protein DUF4446 PF14584.1 KFM12004.1 - 0.081 12.7 0.4 0.15 11.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) ig PF00047.20 KFM12004.1 - 0.097 12.8 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin domain DUF719 PF05334.8 KFM12005.1 - 8.6e-67 224.6 1.7 8.6e-67 224.6 1.2 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF719) LON PF02190.11 KFM12006.1 - 2.1e-24 86.3 0.0 2.9e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_3 PF13920.1 KFM12006.1 - 2.3e-08 33.5 10.1 5.6e-08 32.3 7.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM12006.1 - 2.3e-08 33.8 14.8 7.7e-08 32.2 10.3 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM12006.1 - 6.6e-08 32.2 14.3 6.6e-08 32.2 9.9 2.4 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4 PF00097.20 KFM12006.1 - 4.4e-07 29.4 14.6 4.4e-07 29.4 10.1 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM12006.1 - 1.1e-06 28.2 13.9 3.6e-06 26.6 9.6 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KFM12006.1 - 0.0001 21.9 7.7 0.00076 19.1 5.3 2.4 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KFM12006.1 - 0.00023 20.9 14.3 0.00096 18.9 9.9 2.2 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 KFM12006.1 - 0.0025 17.5 6.3 0.0064 16.2 4.3 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein U-box PF04564.10 KFM12006.1 - 0.0027 17.6 0.0 0.0058 16.5 0.0 1.5 1 0 0 1 1 1 1 U-box domain DUF35_N PF12172.3 KFM12006.1 - 0.0028 17.5 0.3 0.013 15.3 0.2 2.1 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-RING_4 PF14570.1 KFM12006.1 - 0.054 13.0 12.4 0.2 11.2 8.6 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 KFM12006.1 - 0.09 12.8 10.3 0.27 11.3 7.2 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger zf-Apc11 PF12861.2 KFM12006.1 - 1.4 8.7 6.1 0.87 9.4 1.8 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.9 KFM12006.1 - 6 6.4 16.0 3.4 7.2 4.6 2.5 1 1 1 2 2 2 0 P-11 zinc finger Lig_chan PF00060.21 KFM12007.1 - 6.1e-60 201.2 0.0 1e-59 200.4 0.0 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel ANF_receptor PF01094.23 KFM12007.1 - 1.8e-57 194.7 0.0 2.5e-57 194.2 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan-Glu_bd PF10613.4 KFM12007.1 - 3.4e-26 91.0 0.6 1.2e-25 89.2 0.1 2.2 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.15 KFM12007.1 - 6.9e-26 90.8 0.0 1.3e-25 89.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 DUF659 PF04937.10 KFM12007.1 - 0.011 15.2 0.1 0.027 13.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) 7tm_1 PF00001.16 KFM12008.1 - 2.6e-52 177.5 18.2 3.6e-52 177.0 12.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM12008.1 - 4.1e-10 39.2 15.8 8.1e-10 38.2 11.0 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.4 KFM12008.1 - 0.00043 19.5 14.9 0.018 14.2 10.3 2.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.4 KFM12008.1 - 0.0022 17.1 7.4 0.0022 17.1 5.1 2.9 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx Sigma_reg_N PF13800.1 KFM12008.1 - 0.053 13.5 0.2 0.053 13.5 0.1 4.2 3 1 2 5 5 5 0 Sigma factor regulator N-terminal Neur_chan_LBD PF02931.18 KFM12009.1 - 3.7e-56 189.7 0.0 5.2e-56 189.2 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFM12009.1 - 3.2e-46 158.1 1.7 3.4e-37 128.5 1.0 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region NTF2 PF02136.15 KFM12010.1 - 1e-31 109.7 0.2 1.7e-31 108.9 0.2 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 KFM12010.1 - 4.2e-14 51.9 0.0 7.4e-14 51.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM12010.1 - 2.5e-11 43.3 0.0 5.5e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM12010.1 - 0.0002 21.1 0.0 0.00038 20.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3235 PF11574.3 KFM12010.1 - 4.9 7.4 6.2 0.53 10.5 0.5 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3235) HMA PF00403.21 KFM12011.1 - 9.7e-10 38.4 0.1 1.1e-09 38.2 0.1 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain FRD2 PF03197.8 KFM12011.1 - 0.041 14.4 0.4 0.085 13.4 0.1 1.6 1 1 1 2 2 2 0 Bacteriophage FRD2 protein SPARC_Ca_bdg PF10591.4 KFM12012.1 - 1.4e-42 144.3 0.6 2.8e-42 143.3 0.4 1.5 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Kazal_1 PF00050.16 KFM12012.1 - 4.4e-12 45.8 5.0 4.4e-12 45.8 3.5 2.9 3 0 0 3 3 3 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 KFM12012.1 - 4.9e-11 42.3 2.3 4.9e-11 42.3 1.6 2.3 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain FOLN PF09289.5 KFM12012.1 - 2.1e-10 40.2 10.5 2.1e-10 40.2 7.3 2.0 2 0 0 2 2 2 1 Follistatin/Osteonectin-like EGF domain EF-hand_1 PF00036.27 KFM12012.1 - 0.086 12.1 0.3 0.63 9.4 0.0 2.4 3 0 0 3 3 3 0 EF hand EF-hand_6 PF13405.1 KFM12012.1 - 0.11 12.3 0.0 0.69 9.9 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.1 KFM12012.1 - 0.52 10.4 3.1 1.3 9.2 0.1 2.8 2 2 1 3 3 2 0 EF-hand domain pair Cadherin PF00028.12 KFM12013.1 - 0 1577.3 46.1 4.4e-23 81.3 0.0 33.7 34 0 0 34 34 34 33 Cadherin domain Laminin_G_2 PF02210.19 KFM12013.1 - 6.4e-17 61.7 0.2 1.7e-16 60.3 0.2 1.8 1 0 0 1 1 1 1 Laminin G domain EGF PF00008.22 KFM12013.1 - 5.8e-16 58.1 39.6 9.9e-07 28.6 6.5 3.6 3 0 0 3 3 3 3 EGF-like domain Cadherin_2 PF08266.7 KFM12013.1 - 3.9e-15 55.1 0.3 0.92 9.1 0.0 14.8 20 0 0 20 20 20 2 Cadherin-like Laminin_G_1 PF00054.18 KFM12013.1 - 9.8e-12 45.0 0.0 3.4e-11 43.2 0.0 2.1 1 0 0 1 1 1 1 Laminin G domain Laminin_G_3 PF13385.1 KFM12013.1 - 0.00035 20.8 2.0 0.0018 18.5 0.1 3.2 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily EGF_2 PF07974.8 KFM12013.1 - 0.38 10.9 49.9 0.04 14.0 8.4 3.8 3 0 0 3 3 3 0 EGF-like domain Aa_trans PF01490.13 KFM12014.1 - 1.8e-70 237.5 27.8 2.1e-70 237.3 19.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein E1_DerP2_DerF2 PF02221.10 KFM12015.1 - 1.5e-26 93.2 0.0 1.9e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 ML domain Allexi_40kDa PF05549.6 KFM12016.1 - 0.11 11.7 4.7 0.12 11.6 3.3 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein Nicastrin PF05450.10 KFM12016.1 - 0.12 11.6 0.7 0.15 11.2 0.5 1.1 1 0 0 1 1 1 0 Nicastrin FlxA PF14282.1 KFM12016.1 - 0.16 11.9 18.9 0.087 12.7 8.0 2.2 1 1 1 2 2 2 0 FlxA-like protein PDEase_I PF00233.14 KFM12016.1 - 0.16 11.6 2.8 0.25 11.0 1.7 1.4 1 1 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase DUF2383 PF09537.5 KFM12016.1 - 0.22 11.7 5.3 1.1 9.4 0.5 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF2383) DUF342 PF03961.8 KFM12016.1 - 0.29 9.5 10.4 0.15 10.4 5.9 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF342) PilJ PF13675.1 KFM12016.1 - 0.45 10.8 7.6 1 9.6 5.3 1.7 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Spectrin PF00435.16 KFM12016.1 - 0.49 10.6 14.2 1.3 9.3 9.8 1.9 1 1 0 1 1 1 0 Spectrin repeat Sigma70_ner PF04546.8 KFM12016.1 - 0.54 9.8 10.6 0.6 9.6 7.4 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region ApoO PF09769.4 KFM12016.1 - 0.99 9.1 5.5 11 5.7 3.8 2.0 1 1 0 1 1 1 0 Apolipoprotein O Prefoldin_2 PF01920.15 KFM12016.1 - 1.1 9.0 14.8 0.2 11.4 2.6 2.9 1 1 2 3 3 3 0 Prefoldin subunit 5_nucleotid PF05761.9 KFM12016.1 - 1.3 7.4 5.8 1.9 6.9 4.0 1.2 1 0 0 1 1 1 0 5' nucleotidase family Fib_alpha PF08702.5 KFM12016.1 - 1.8 8.6 8.6 22 5.1 6.0 2.1 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.7 KFM12016.1 - 2.1 8.1 6.4 2.5 7.9 3.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TBPIP PF07106.8 KFM12016.1 - 2.3 7.7 12.2 1.5 8.2 7.3 1.5 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FUSC PF04632.7 KFM12016.1 - 2.9 6.2 5.7 3.4 5.9 4.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3584 PF12128.3 KFM12016.1 - 3.3 4.8 19.0 4 4.6 13.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Syntaxin-6_N PF09177.6 KFM12016.1 - 3.7 8.0 8.4 15 6.0 5.8 2.0 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Fzo_mitofusin PF04799.8 KFM12016.1 - 4.8 6.5 7.8 5.4 6.3 5.2 1.3 1 1 0 1 1 1 0 fzo-like conserved region DivIVA PF05103.8 KFM12016.1 - 5.4 7.0 15.5 0.24 11.4 0.9 2.3 1 1 1 2 2 2 0 DivIVA protein APG6 PF04111.7 KFM12016.1 - 5.5 5.9 17.9 6.8 5.6 12.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 YjcZ PF13990.1 KFM12016.1 - 6.2 5.8 12.5 7.2 5.6 8.7 1.0 1 0 0 1 1 1 0 YjcZ-like protein Mnd1 PF03962.10 KFM12016.1 - 7.5 6.1 16.6 36 3.9 11.5 1.8 1 1 0 1 1 1 0 Mnd1 family AA_permease_2 PF13520.1 KFM12017.1 - 1.7e-48 165.2 22.5 1.7e-48 165.2 15.6 2.0 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.16 KFM12017.1 - 4.9e-42 143.8 21.8 4.9e-42 143.8 15.1 2.1 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.1 KFM12017.1 - 2.8e-19 68.7 7.9 2.8e-19 68.7 5.5 3.7 5 0 0 5 5 5 1 C-terminus of AA_permease Annexin PF00191.15 KFM12018.1 - 4e-181 587.2 35.5 1.7e-24 85.4 0.1 8.1 8 0 0 8 8 8 8 Annexin Sigma70_ner PF04546.8 KFM12018.1 - 0.1 12.1 3.2 5.9 6.4 0.1 3.1 3 0 0 3 3 3 0 Sigma-70, non-essential region RuvC PF02075.12 KFM12018.1 - 0.12 12.1 0.1 21 4.8 0.0 3.3 3 0 0 3 3 3 0 Crossover junction endodeoxyribonuclease RuvC GSHPx PF00255.14 KFM12020.1 - 7.5e-23 79.9 0.1 1.1e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase Dynactin_p62 PF05502.8 KFM12021.1 - 1.6e-101 340.5 18.4 3.1e-66 224.1 0.7 2.3 1 1 1 2 2 2 2 Dynactin p62 family RRM_1 PF00076.17 KFM12022.1 - 5.4e-12 45.1 0.1 8.6e-12 44.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM12022.1 - 1.2e-11 44.4 0.0 2e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM12022.1 - 5.7e-11 42.0 0.3 1.1e-10 41.2 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFM12022.1 - 7.8e-05 22.3 0.0 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 KFM12022.1 - 0.0033 17.0 1.4 0.0033 17.0 1.0 2.6 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_3 PF08777.6 KFM12022.1 - 0.0038 17.0 0.0 0.0074 16.1 0.0 1.4 1 0 0 1 1 1 1 RNA binding motif FYVE PF01363.16 KFM12022.1 - 0.0067 16.2 1.1 0.0067 16.2 0.7 1.7 2 0 0 2 2 2 1 FYVE zinc finger zf-CCCH_2 PF14608.1 KFM12022.1 - 0.034 14.1 0.8 0.034 14.1 0.5 2.2 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Calsarcin PF05556.6 KFM12023.1 - 1.8e-54 184.8 0.1 2.5e-54 184.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-binding protein (Calsarcin) HSNSD PF12062.3 KFM12024.1 - 6.5e-263 872.4 0.0 9.5e-263 871.8 0.0 1.2 1 0 0 1 1 1 1 heparan sulfate-N-deacetylase Sulfotransfer_1 PF00685.22 KFM12024.1 - 1.5e-46 158.8 0.0 2.4e-46 158.1 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 KFM12024.1 - 0.0084 17.0 2.3 0.01 16.7 0.1 2.3 2 1 0 2 2 2 1 Sulfotransferase family Ribosomal_S11 PF00411.14 KFM12025.1 - 8.6e-41 138.5 0.2 1.1e-40 138.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 MHCassoc_trimer PF08831.5 KFM12026.1 - 8.6e-37 124.8 8.9 1.3e-36 124.3 6.1 1.2 1 0 0 1 1 1 1 Class II MHC-associated invariant chain trimerisation domain MHC2-interact PF09307.5 KFM12026.1 - 1.3e-07 31.3 1.3 2.8e-07 30.2 0.9 1.5 1 0 0 1 1 1 1 CLIP, MHC2 interacting DUF365 PF04033.7 KFM12026.1 - 0.11 12.4 0.2 0.17 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF365) Treacle PF03546.9 KFM12028.1 - 0.00026 19.9 17.5 0.00026 19.9 12.1 5.6 1 1 4 5 5 5 3 Treacher Collins syndrome protein Treacle Sulfatase PF00884.18 KFM12029.1 - 1.7e-70 237.6 0.1 2.3e-70 237.2 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 KFM12029.1 - 0.0038 17.5 0.0 0.015 15.5 0.0 2.1 2 1 0 2 2 2 1 C-terminal region of aryl-sulfatase SNF PF00209.13 KFM12030.1 - 7.6e-227 753.9 37.0 8.8e-227 753.6 25.6 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Caudal_act PF04731.7 KFM12031.1 - 4.2e-47 159.9 16.4 7.8e-47 159.0 11.3 1.4 1 0 0 1 1 1 1 Caudal like protein activation region Homeobox PF00046.24 KFM12031.1 - 2e-21 75.3 2.2 3.3e-21 74.6 1.5 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFM12031.1 - 0.041 13.5 0.4 0.1 12.3 0.3 1.7 1 0 0 1 1 1 0 Homeobox KN domain Pkinase_Tyr PF07714.12 KFM12032.1 - 8.2e-108 359.3 0.0 1.2e-107 358.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM12032.1 - 3e-48 164.2 0.0 4.1e-29 101.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain I-set PF07679.11 KFM12032.1 - 2.3e-27 94.6 4.9 2e-10 40.4 0.1 4.9 4 1 0 4 4 4 4 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM12032.1 - 3.9e-21 74.9 11.6 3.8e-11 42.9 0.0 5.8 5 2 0 5 5 5 4 Immunoglobulin domain ig PF00047.20 KFM12032.1 - 6.4e-16 58.2 10.4 2e-06 27.8 0.0 6.3 5 1 0 5 5 5 3 Immunoglobulin domain Ig_3 PF13927.1 KFM12032.1 - 5.6e-14 52.3 13.3 0.0001 22.7 0.2 5.7 5 1 1 6 6 6 4 Immunoglobulin domain V-set PF07686.12 KFM12032.1 - 7e-09 35.5 4.3 1.3e-05 25.0 0.1 4.5 4 1 0 4 4 4 2 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM12032.1 - 2.9e-05 23.9 6.8 0.19 11.6 0.0 4.7 4 1 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Herpes_gI PF01688.12 KFM12032.1 - 0.047 12.8 0.0 2.6 7.1 0.0 2.5 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein I Pkinase_Tyr PF07714.12 KFM12033.1 - 1.3e-106 355.4 0.0 2e-106 354.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM12033.1 - 1.9e-44 151.7 0.0 1.4e-26 93.2 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain I-set PF07679.11 KFM12033.1 - 8.5e-31 105.6 0.0 4.4e-09 36.0 0.0 6.1 6 0 0 6 6 6 5 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM12033.1 - 4.2e-26 90.8 4.6 3.6e-06 27.0 0.0 5.8 4 1 1 5 5 5 4 Immunoglobulin domain Ig_3 PF13927.1 KFM12033.1 - 8.1e-20 71.0 11.9 9.2e-06 26.0 0.0 6.1 5 1 0 5 5 5 4 Immunoglobulin domain ig PF00047.20 KFM12033.1 - 2.8e-13 49.7 5.0 1.4e-05 25.1 0.0 4.9 5 0 0 5 5 5 3 Immunoglobulin domain V-set PF07686.12 KFM12033.1 - 1.3e-11 44.3 11.2 0.0049 16.7 0.6 6.3 4 3 1 5 5 5 3 Immunoglobulin V-set domain C2-set PF05790.10 KFM12033.1 - 0.00013 21.8 0.2 1.9 8.5 0.0 3.9 4 0 0 4 4 4 1 Immunoglobulin C2-set domain APH PF01636.18 KFM12033.1 - 0.001 18.8 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family HMG_box_2 PF09011.5 KFM12034.1 - 2.5e-11 43.7 0.4 5.5e-11 42.6 0.2 1.6 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.14 KFM12034.1 - 3.9e-11 43.0 0.4 9.7e-11 41.7 0.3 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box Zn_Tnp_IS91 PF14319.1 KFM12034.1 - 0.19 11.2 3.0 1.2 8.6 0.1 3.0 3 0 0 3 3 3 0 Transposase zinc-binding domain 7tm_1 PF00001.16 KFM12035.1 - 8.1e-57 192.2 21.2 9.7e-57 192.0 14.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM12035.1 - 1.2e-11 44.3 18.6 1.7e-11 43.7 12.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM12035.1 - 0.00045 19.4 12.3 0.00045 19.4 8.6 2.3 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Cyclin_N PF00134.18 KFM12035.1 - 0.031 13.8 0.1 0.055 13.0 0.1 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain Pkinase_Tyr PF07714.12 KFM12036.1 - 4.7e-105 350.3 0.0 7.7e-105 349.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM12036.1 - 1.4e-45 155.5 0.0 6.2e-32 110.7 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain I-set PF07679.11 KFM12036.1 - 8.7e-44 147.2 9.7 1.3e-14 53.8 0.0 7.7 6 1 2 8 8 8 4 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM12036.1 - 3.3e-43 145.6 12.8 1.8e-08 34.3 0.0 7.3 7 0 0 7 7 7 6 Immunoglobulin domain Ig_3 PF13927.1 KFM12036.1 - 4.3e-33 113.5 6.7 1.9e-07 31.4 0.0 8.2 7 1 0 7 7 7 5 Immunoglobulin domain V-set PF07686.12 KFM12036.1 - 2.4e-21 75.7 12.7 7.1e-05 22.6 0.1 7.4 6 2 0 6 6 6 5 Immunoglobulin V-set domain ig PF00047.20 KFM12036.1 - 6.5e-20 71.0 15.4 8.7e-05 22.5 0.2 7.5 6 2 0 6 6 6 4 Immunoglobulin domain C1-set PF07654.10 KFM12036.1 - 1.8e-06 27.8 1.7 0.016 15.2 0.0 5.1 5 0 0 5 5 5 1 Immunoglobulin C1-set domain C2-set_2 PF08205.7 KFM12036.1 - 3.6e-05 23.5 8.2 0.21 11.5 0.0 4.7 6 0 0 6 6 6 2 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.11 KFM12036.1 - 0.00017 20.0 0.1 0.29 9.3 0.0 3.7 3 1 0 4 4 4 2 Alphaherpesvirus glycoprotein E Receptor_2B4 PF11465.3 KFM12036.1 - 0.0026 17.6 4.8 0.23 11.4 0.0 4.1 5 0 0 5 5 5 1 Natural killer cell receptor 2B4 Lamprin PF06403.6 KFM12037.1 - 8.8e-05 22.2 10.3 0.0016 18.2 7.2 2.0 1 1 0 1 1 1 1 Lamprin Chorion_1 PF01723.11 KFM12037.1 - 8.6 6.2 9.2 82 3.0 6.3 2.0 1 1 0 1 1 1 0 Chorion protein zf-RING_2 PF13639.1 KFM12038.1 - 5.3e-13 48.5 11.7 8.9e-13 47.8 8.1 1.4 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 KFM12038.1 - 2.1e-11 43.4 0.0 3.8e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.2 KFM12038.1 - 5.2e-08 32.8 6.1 1e-07 31.9 4.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KFM12038.1 - 1.9e-07 30.6 10.9 3.3e-07 29.8 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM12038.1 - 2.2e-07 30.4 10.2 3.6e-07 29.7 7.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFM12038.1 - 4.8e-06 26.1 8.3 7.9e-06 25.4 5.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM12038.1 - 7.7e-06 25.8 11.5 1.4e-05 25.0 8.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFM12038.1 - 0.013 15.3 5.4 0.026 14.3 3.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger CoA_binding_3 PF13727.1 KFM12038.1 - 0.07 12.9 0.1 0.17 11.7 0.0 1.6 2 0 0 2 2 2 0 CoA-binding domain DUF2254 PF10011.4 KFM12038.1 - 0.11 10.8 0.9 0.14 10.6 0.0 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) zf-RING_UBOX PF13445.1 KFM12038.1 - 0.22 11.2 6.2 0.54 10.0 4.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger UPF0233 PF06781.7 KFM12038.1 - 0.23 11.0 1.8 2.8 7.6 0.6 2.6 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0233) Prok-RING_1 PF14446.1 KFM12038.1 - 0.99 9.1 10.8 0.17 11.6 2.2 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.24 KFM12038.1 - 2.8 7.6 10.5 4.9 6.9 7.3 1.4 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.2 KFM12038.1 - 4.2 7.5 9.5 9.8 6.3 6.6 1.6 1 0 0 1 1 1 0 RING-variant domain ZZ PF00569.12 KFM12040.1 - 1.7e-12 46.6 3.5 3e-12 45.8 2.4 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type PB1 PF00564.19 KFM12040.1 - 0.0017 17.9 0.0 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 PB1 domain FlaG PF03646.10 KFM12040.1 - 1.9 8.6 8.0 6.7 6.9 0.1 2.5 1 1 1 2 2 2 0 FlaG protein DnaJ_CXXCXGXG PF00684.14 KFM12040.1 - 6.6 6.8 9.4 3 7.9 0.2 2.4 1 1 1 2 2 2 0 DnaJ central domain Archaeal_AmoA PF12942.2 KFM12041.1 - 0.23 11.2 6.8 0.25 11.1 4.7 1.2 1 0 0 1 1 1 0 Archaeal ammonia monooxygenase subunit A (AmoA) Calreticulin PF00262.13 KFM12042.1 - 6.8e-162 538.2 16.8 1.1e-161 537.5 11.6 1.4 1 0 0 1 1 1 1 Calreticulin family DUF1510 PF07423.6 KFM12042.1 - 0.00095 18.5 7.8 0.00095 18.5 5.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) Ycf1 PF05758.7 KFM12042.1 - 0.021 12.6 4.0 0.03 12.0 2.8 1.1 1 0 0 1 1 1 0 Ycf1 MAPEG PF01124.13 KFM12043.1 - 8.4e-16 57.7 5.6 8.4e-16 57.7 3.9 1.5 1 1 1 2 2 2 1 MAPEG family dNK PF01712.14 KFM12044.1 - 2.8e-42 144.0 2.4 4.1e-42 143.5 1.6 1.2 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.1 KFM12044.1 - 2.7e-08 34.1 0.0 9.5e-08 32.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFM12044.1 - 9.9e-05 22.2 0.0 0.0013 18.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFM12044.1 - 0.0074 17.1 0.5 0.037 14.8 0.3 2.3 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 KFM12044.1 - 0.0092 15.3 0.0 0.16 11.2 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase AAA_28 PF13521.1 KFM12044.1 - 0.014 15.3 0.1 0.035 14.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain RRM_6 PF14259.1 KFM12045.1 - 6.4e-29 99.7 0.0 2e-13 50.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFM12045.1 - 5.6e-25 86.7 0.0 3.4e-13 48.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RNPHF PF08080.7 KFM12045.1 - 4.4e-13 48.4 14.3 4.4e-13 48.4 9.9 2.4 2 1 0 2 2 2 1 RNPHF zinc finger RRM_5 PF13893.1 KFM12045.1 - 2.3e-05 24.1 0.0 0.19 11.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFM12045.1 - 0.0072 16.1 0.0 2.9 7.7 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif Limkain-b1 PF11608.3 KFM12045.1 - 0.15 11.8 0.1 0.54 10.0 0.0 1.9 2 0 0 2 2 2 0 Limkain b1 RUN PF02759.14 KFM12046.1 - 6.2e-31 106.9 0.0 1.4e-30 105.8 0.0 1.6 1 0 0 1 1 1 1 RUN domain Filament PF00038.16 KFM12046.1 - 0.036 13.5 17.6 0.28 10.6 12.2 2.0 1 1 0 1 1 1 0 Intermediate filament protein CASP_C PF08172.7 KFM12046.1 - 0.18 10.7 6.2 2.9 6.8 1.0 2.4 2 0 0 2 2 2 0 CASP C terminal DUF948 PF06103.6 KFM12046.1 - 5.5 6.9 7.6 5.9 6.8 2.0 2.9 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) UPF0449 PF15136.1 KFM12046.1 - 9 6.5 8.5 2.4 8.4 0.0 3.0 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF1664 PF07889.7 KFM12046.1 - 9.4 6.0 10.0 0.5 10.1 0.2 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Pep_M12B_propep PF01562.14 KFM12047.1 - 1.8e-27 95.7 0.0 3.1e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_spacer1 PF05986.9 KFM12047.1 - 4.3e-25 87.7 0.0 8e-25 86.9 0.0 1.5 1 0 0 1 1 1 1 ADAM-TS Spacer 1 TSP_1 PF00090.14 KFM12047.1 - 1.1e-21 76.6 59.4 1.2e-09 38.1 4.5 5.9 6 0 0 6 6 6 4 Thrombospondin type 1 domain Reprolysin PF01421.14 KFM12047.1 - 6.3e-20 71.6 0.0 1.3e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.1 KFM12047.1 - 3.6e-14 53.1 0.1 7.8e-14 52.0 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KFM12047.1 - 1.1e-11 45.3 0.1 2.3e-11 44.2 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFM12047.1 - 1.2e-10 41.7 0.3 2.5e-10 40.7 0.2 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFM12047.1 - 1e-08 34.9 0.1 2.1e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KFM12047.1 - 0.00034 20.3 0.1 0.00077 19.2 0.1 1.6 1 0 0 1 1 1 1 Matrixin PLAC PF08686.6 KFM12047.1 - 0.0036 17.5 7.4 0.0036 17.5 5.1 3.4 3 0 0 3 3 3 1 PLAC (protease and lacunin) domain Peptidase_M7 PF02031.11 KFM12047.1 - 0.05 13.2 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family Exo_endo_phos PF03372.18 KFM12049.1 - 6.3e-22 78.7 0.0 8.3e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 KFM12049.1 - 1e-15 56.9 16.4 1e-09 37.7 1.2 3.2 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM12049.1 - 3.6e-13 49.0 22.1 3.8e-10 39.3 5.6 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 KFM12049.1 - 7.1e-06 25.3 22.8 0.021 14.7 0.1 5.8 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 KFM12049.1 - 2.4e-05 23.7 14.0 0.47 10.8 0.1 5.3 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 KFM12049.1 - 0.0018 18.1 10.4 1.3 9.3 0.1 4.8 4 0 0 4 4 4 2 Leucine Rich repeat DUF713 PF05218.9 KFM12049.1 - 0.074 12.7 0.9 0.19 11.4 0.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF713) SIS PF01380.17 KFM12050.1 - 1.2e-63 212.5 0.0 1.4e-34 118.4 0.0 2.4 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 KFM12050.1 - 5e-28 97.8 0.0 3.4e-21 75.3 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KFM12050.1 - 3.1e-17 62.7 0.0 6.6e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KFM12050.1 - 8.5e-15 54.5 0.0 2.7e-14 52.9 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.1 KFM12050.1 - 3.5e-08 32.4 0.0 5.8e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 KFM12050.1 - 0.003 17.2 0.0 0.012 15.3 0.0 2.0 1 1 0 1 1 1 1 SIS domain Acetyltransf_6 PF13480.1 KFM12050.1 - 0.12 12.3 0.0 0.4 10.6 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Pkinase PF00069.20 KFM12051.1 - 1.3e-66 224.4 0.0 1.6e-66 224.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM12051.1 - 1.5e-29 102.8 0.1 2.1e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFM12051.1 - 3.4e-06 26.2 0.2 5.6e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFM12051.1 - 0.00034 20.4 0.0 0.00062 19.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KFM12051.1 - 0.00035 19.9 0.2 0.00061 19.1 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 KFM12051.1 - 0.00087 18.3 0.1 0.0037 16.2 0.0 1.9 2 0 0 2 2 2 1 Kinase-like DUF1651 PF07864.6 KFM12051.1 - 0.055 13.5 0.2 0.14 12.2 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1651) RasGEF PF00617.14 KFM12053.1 - 3.3e-50 170.4 0.1 6.1e-50 169.5 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KFM12053.1 - 1.4e-14 54.0 0.1 4.6e-14 52.3 0.1 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif DUF948 PF06103.6 KFM12053.1 - 0.13 12.1 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Pkinase PF00069.20 KFM12054.1 - 4.5e-66 222.6 0.9 7.6e-66 221.9 0.6 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM12054.1 - 4e-26 91.6 1.2 1.8e-25 89.5 0.1 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Aminotran_3 PF00202.16 KFM12055.1 - 2.3e-78 263.4 0.0 2.7e-78 263.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 KFM12055.1 - 0.00049 19.1 0.0 0.00079 18.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DUF3301 PF11743.3 KFM12055.1 - 0.045 13.2 0.0 0.09 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) RRM_1 PF00076.17 KFM12056.1 - 2.3e-40 136.0 0.7 3.7e-19 68.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM12056.1 - 7.4e-31 105.9 0.1 2.8e-14 52.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM12056.1 - 2.1e-08 33.8 0.1 0.0029 17.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFM12056.1 - 2.4e-06 27.3 0.1 0.082 12.7 0.0 2.4 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 KFM12056.1 - 7.1e-06 25.7 0.0 0.00045 19.9 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif NID PF07292.8 KFM12056.1 - 0.00056 19.8 0.6 0.15 12.1 0.1 2.6 2 1 0 3 3 3 2 Nmi/IFP 35 domain (NID) NDK PF00334.14 KFM12057.1 - 9.6e-37 125.7 0.0 1.2e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Dpy-30 PF05186.8 KFM12057.1 - 1.3e-18 66.2 0.4 2e-18 65.5 0.3 1.3 1 0 0 1 1 1 1 Dpy-30 motif wnt PF00110.14 KFM12058.1 - 9.4e-106 353.4 27.4 1.1e-105 353.2 19.0 1.0 1 0 0 1 1 1 1 wnt family Thymosin PF01290.15 KFM12059.1 - 2.7e-21 74.8 10.7 2.9e-21 74.7 7.4 1.0 1 0 0 1 1 1 1 Thymosin beta-4 family WH2 PF02205.15 KFM12059.1 - 0.0012 18.3 0.1 0.0017 17.9 0.1 1.2 1 0 0 1 1 1 1 WH2 motif RhoGAP PF00620.22 KFM12060.1 - 4.2e-37 127.0 1.4 3.6e-36 124.0 0.0 2.7 3 0 0 3 3 3 1 RhoGAP domain Drc1-Sld2 PF11719.3 KFM12060.1 - 0.0019 17.3 31.0 0.0021 17.2 6.8 3.2 3 1 1 4 4 4 2 DNA replication and checkpoint protein PKD_channel PF08016.7 KFM12061.1 - 3.9e-135 450.5 21.9 5.6e-135 450.0 15.2 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 KFM12061.1 - 9.9e-23 80.4 32.3 9.9e-23 80.4 22.4 1.8 2 0 0 2 2 2 1 Ion transport protein I-set PF07679.11 KFM12062.1 - 4.5e-40 135.3 0.0 2.7e-20 72.0 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM12062.1 - 2.2e-17 62.9 0.0 4.3e-08 33.1 0.0 2.9 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.12 KFM12062.1 - 3.1e-08 33.5 0.0 0.00035 20.4 0.0 3.0 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_3 PF13927.1 KFM12062.1 - 1.2e-07 32.1 0.7 0.004 17.6 0.0 3.8 3 1 0 3 3 3 2 Immunoglobulin domain ig PF00047.20 KFM12062.1 - 1.7e-07 31.2 0.0 0.0071 16.4 0.0 3.0 2 0 0 2 2 2 2 Immunoglobulin domain DUF2457 PF10446.4 KFM12062.1 - 0.012 14.3 2.4 0.02 13.6 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) I-set PF07679.11 KFM12063.1 - 4.8e-19 68.0 0.0 6.9e-19 67.5 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM12063.1 - 5.3e-07 29.6 0.0 1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFM12063.1 - 1.7e-05 25.2 0.0 0.00034 21.0 0.0 2.3 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFM12063.1 - 0.00012 21.9 0.0 0.00033 20.5 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 KFM12063.1 - 0.0044 17.0 0.0 0.009 16.1 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain 7tm_1 PF00001.16 KFM12064.1 - 2.2e-57 194.1 22.1 2.8e-57 193.8 15.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 KFM12064.1 - 1.3e-05 24.4 19.1 1.3e-05 24.4 13.3 2.4 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.4 KFM12064.1 - 1.3e-05 24.4 21.8 8.3e-05 21.8 15.1 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Baculo_11_kDa PF06143.6 KFM12064.1 - 0.064 12.6 1.2 0.33 10.3 0.9 2.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family Adipogenin PF15202.1 KFM12064.1 - 0.22 11.4 7.9 1.5 8.6 0.1 3.7 3 0 0 3 3 3 0 Adipogenin Kelch_1 PF01344.20 KFM12065.1 - 7.4e-75 246.2 16.0 2.9e-15 55.5 0.2 6.7 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.1 KFM12065.1 - 1.9e-41 138.5 3.3 1.2e-07 31.6 0.0 6.4 2 2 4 6 6 6 6 Kelch motif BACK PF07707.10 KFM12065.1 - 5.5e-37 125.7 0.7 1.5e-36 124.3 0.5 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.26 KFM12065.1 - 2.3e-32 111.2 0.9 4.8e-32 110.2 0.6 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_3 PF13415.1 KFM12065.1 - 6.8e-31 105.7 10.3 2.3e-06 27.5 0.1 6.2 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.10 KFM12065.1 - 1.4e-27 94.3 6.1 6.6e-05 22.5 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.1 KFM12065.1 - 6.3e-25 86.6 4.4 2.5e-05 23.9 0.0 6.2 4 1 2 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 KFM12065.1 - 1.4e-07 31.2 14.7 0.43 10.5 0.2 5.4 5 0 0 5 5 5 4 Kelch motif Skp1_POZ PF03931.10 KFM12065.1 - 0.022 14.8 0.2 0.068 13.2 0.0 1.9 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain Ashwin PF15323.1 KFM12065.1 - 0.033 14.2 0.6 0.033 14.2 0.4 1.8 2 0 0 2 2 2 0 Developmental protein PQQ_3 PF13570.1 KFM12065.1 - 2.1 8.7 12.0 25 5.3 0.0 4.7 5 0 0 5 5 5 0 PQQ-like domain MH2 PF03166.9 KFM12066.1 - 8.1e-79 263.6 0.2 1.1e-78 263.2 0.2 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.11 KFM12066.1 - 2.1e-42 143.2 0.3 4.9e-42 142.1 0.2 1.6 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.4 KFM12066.1 - 2.7e-07 30.3 0.0 5.4e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Interferon-regulatory factor 3 Fasciclin PF02469.17 KFM12067.1 - 3.5e-110 363.2 3.1 4.8e-32 110.6 0.1 4.1 4 0 0 4 4 4 4 Fasciclin domain DNA_Packaging PF11053.3 KFM12067.1 - 0.032 13.8 0.4 0.21 11.2 0.0 2.5 4 0 0 4 4 4 0 Terminase DNA packaging enzyme Peptidase_M23 PF01551.17 KFM12069.1 - 5.1e-12 45.6 0.0 3.3e-05 23.8 0.0 2.3 2 0 0 2 2 2 2 Peptidase family M23 zf-A20 PF01754.11 KFM12069.1 - 0.32 10.6 9.4 0.62 9.6 0.9 2.6 2 0 0 2 2 2 0 A20-like zinc finger F-box-like PF12937.2 KFM12070.1 - 5e-11 42.1 2.9 5.9e-11 41.9 0.8 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KFM12070.1 - 2.9e-10 39.5 1.1 2.9e-10 39.5 0.8 2.3 2 0 0 2 2 2 1 F-box domain DUF4354 PF14263.1 KFM12070.1 - 0.029 14.0 0.2 3.5 7.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) PixA PF12306.3 KFM12070.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Inclusion body protein IL7 PF01415.11 KFM12071.1 - 0.00057 19.5 2.1 0.00071 19.2 1.5 1.2 1 0 0 1 1 1 1 Interleukin 7/9 family Humanin PF15040.1 KFM12071.1 - 0.026 13.7 0.7 0.069 12.3 0.5 1.6 1 0 0 1 1 1 0 Humanin family Mito_carr PF00153.22 KFM12072.1 - 1.4e-60 200.9 2.6 1.9e-22 78.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF787 PF05619.6 KFM12072.1 - 0.0012 17.6 0.0 0.002 16.8 0.0 1.3 1 0 0 1 1 1 1 Borrelia burgdorferi protein of unknown function (DUF787) Jiraiya PF15038.1 KFM12072.1 - 0.16 11.3 0.2 0.39 10.1 0.1 1.6 2 0 0 2 2 2 0 Jiraiya IL8 PF00048.15 KFM12074.1 - 1.9e-08 34.1 1.2 2.7e-08 33.6 0.8 1.2 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like KASH PF10541.4 KFM12074.1 - 0.2 11.5 1.2 0.35 10.7 0.8 1.3 1 0 0 1 1 1 0 Nuclear envelope localisation domain Macro PF01661.16 KFM12075.1 - 1.9e-26 92.3 0.0 3.4e-26 91.4 0.0 1.5 1 0 0 1 1 1 1 Macro domain Histone PF00125.19 KFM12075.1 - 1.4e-22 79.5 0.1 4e-22 78.1 0.0 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFM12075.1 - 0.0062 16.5 0.0 0.021 14.8 0.0 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Clp_N PF02861.15 KFM12075.1 - 0.025 14.4 0.0 0.07 13.0 0.0 1.8 1 0 0 1 1 1 0 Clp amino terminal domain YihI PF04220.7 KFM12075.1 - 0.11 11.7 5.1 3.3 7.0 0.0 2.3 2 0 0 2 2 2 0 Der GTPase activator (YihI) OAR PF03826.12 KFM12076.1 - 1.9e-09 36.6 1.0 4.2e-09 35.6 0.7 1.6 1 0 0 1 1 1 1 OAR domain Homeobox PF00046.24 KFM12076.1 - 0.055 13.0 7.1 0.087 12.4 4.9 1.3 1 0 0 1 1 1 0 Homeobox domain Pterin_4a PF01329.14 KFM12077.1 - 2.7e-31 107.1 0.3 3e-31 107.0 0.2 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase IF-2 PF11987.3 KFM12077.1 - 0.016 15.0 0.0 0.077 12.8 0.0 1.8 1 1 0 2 2 2 0 Translation-initiation factor 2 Ion_trans PF00520.26 KFM12077.1 - 0.13 11.4 0.1 0.14 11.3 0.1 1.1 1 0 0 1 1 1 0 Ion transport protein Thioredoxin PF00085.15 KFM12078.1 - 8.4e-11 41.4 0.0 1.3e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.1 KFM12078.1 - 0.1 12.1 0.0 0.55 9.8 0.0 1.9 1 1 1 2 2 2 0 Thioredoxin DEAD PF00270.24 KFM12080.1 - 1e-46 158.5 0.0 7.3e-46 155.7 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFM12080.1 - 5.9e-23 80.5 0.0 2.9e-22 78.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KFM12080.1 - 5.2e-05 22.1 0.0 0.00039 19.3 0.0 2.4 2 1 1 3 3 3 1 SNF2 family N-terminal domain CAML PF14963.1 KFM12081.1 - 2.7e-106 354.7 0.0 3e-106 354.6 0.0 1.0 1 0 0 1 1 1 1 Calcium signal-modulating cyclophilin ligand Sec23_trunk PF04811.10 KFM12082.1 - 1.2e-84 283.4 0.1 2.3e-84 282.5 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KFM12082.1 - 9e-25 86.1 0.7 1.9e-24 85.0 0.5 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KFM12082.1 - 1e-20 74.0 0.0 2.6e-20 72.7 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KFM12082.1 - 6.3e-16 57.6 5.3 1.1e-15 56.9 3.2 1.8 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KFM12082.1 - 1e-10 41.1 0.0 2.4e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Sen15 PF09631.5 KFM12082.1 - 0.053 13.7 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 Sen15 protein DUF987 PF06174.6 KFM12082.1 - 0.12 11.8 0.3 0.53 9.8 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF987) Arf PF00025.16 KFM12083.1 - 2e-61 206.2 0.0 2.2e-61 206.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KFM12083.1 - 7.2e-10 38.1 0.1 2.7e-07 29.6 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 KFM12083.1 - 3e-09 36.3 0.0 3.8e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KFM12083.1 - 4.2e-07 30.4 0.0 6.3e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 KFM12083.1 - 8.2e-07 28.5 0.0 8.7e-07 28.4 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 KFM12083.1 - 9.4e-06 25.5 0.0 1.3e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFM12083.1 - 0.0002 20.8 0.0 0.0027 17.1 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFM12083.1 - 0.0011 18.1 0.0 0.0012 18.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 KFM12083.1 - 0.093 12.2 0.0 0.28 10.6 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation zf-HC5HC2H_2 PF13832.1 KFM12084.1 - 2.4e-30 104.7 8.0 2.4e-30 104.7 5.5 2.8 3 0 0 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KFM12084.1 - 6.3e-23 80.7 8.0 6.3e-23 80.7 5.5 3.7 4 0 0 4 4 4 1 PHD-like zinc-binding domain EPL1 PF10513.4 KFM12084.1 - 8.3e-16 58.6 0.6 8.3e-16 58.6 0.4 2.9 2 1 0 2 2 2 1 Enhancer of polycomb-like PHD_2 PF13831.1 KFM12084.1 - 9.7e-13 47.2 6.7 9.7e-13 47.2 4.6 3.8 4 0 0 4 4 4 1 PHD-finger PHD PF00628.24 KFM12084.1 - 1.7e-09 37.2 8.1 1.7e-09 37.2 5.6 3.3 3 0 0 3 3 3 2 PHD-finger C1_1 PF00130.17 KFM12084.1 - 0.0039 16.8 4.3 0.0039 16.8 3.0 3.4 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) UQ_con PF00179.21 KFM12085.1 - 2.6e-46 156.5 0.2 2.1e-38 130.9 0.2 2.0 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFM12085.1 - 1.7e-05 24.5 0.0 2.2e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KFM12085.1 - 0.0047 16.7 0.2 0.0061 16.4 0.1 1.5 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 KFM12085.1 - 0.016 14.9 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 UEV domain Metallophos PF00149.23 KFM12086.1 - 2.1e-41 141.5 0.7 2.7e-41 141.1 0.5 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Skp1 PF01466.14 KFM12087.1 - 9.2e-41 137.7 0.8 1.6e-40 137.0 0.5 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 KFM12087.1 - 3.2e-29 100.7 0.6 8.5e-29 99.4 0.1 1.9 2 1 0 2 2 2 1 Skp1 family, tetramerisation domain CTNNB1_binding PF08347.6 KFM12088.1 - 9.9e-32 110.8 6.0 9.9e-32 110.8 4.2 2.4 2 1 1 3 3 3 1 N-terminal CTNNB1 binding HMG_box PF00505.14 KFM12088.1 - 2.3e-22 79.0 1.0 4.6e-22 78.0 0.7 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFM12088.1 - 2e-08 34.4 1.1 6e-08 32.9 0.7 1.8 1 0 0 1 1 1 1 HMG-box domain MAT_Alpha1 PF04769.7 KFM12088.1 - 0.0047 16.2 0.3 0.0073 15.6 0.2 1.2 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 Porin_3 PF01459.17 KFM12090.1 - 1.2e-76 257.5 3.1 1.4e-76 257.4 2.2 1.0 1 0 0 1 1 1 1 Eukaryotic porin DUF4534 PF15049.1 KFM12091.1 - 0.0078 15.8 0.3 0.012 15.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4534) Borrelia_REV PF03978.8 KFM12091.1 - 0.06 13.0 1.6 0.12 12.0 0.2 2.1 1 1 1 2 2 2 0 Borrelia burgdorferi REV protein Atrophin-1 PF03154.10 KFM12091.1 - 0.12 10.4 1.8 0.16 10.1 1.2 1.1 1 0 0 1 1 1 0 Atrophin-1 family I-set PF07679.11 KFM12092.1 - 1.4e-25 88.9 0.0 2.7e-15 55.9 0.0 3.5 4 0 0 4 4 3 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM12092.1 - 6.6e-20 71.0 0.0 1.9e-09 37.5 0.0 3.0 3 0 0 3 3 3 2 Immunoglobulin domain Ig_3 PF13927.1 KFM12092.1 - 2.4e-18 66.3 1.3 6.9e-12 45.6 0.0 3.4 4 0 0 4 4 2 2 Immunoglobulin domain ig PF00047.20 KFM12092.1 - 8.2e-12 45.0 0.2 5e-05 23.3 0.0 3.8 3 2 0 3 3 3 2 Immunoglobulin domain V-set PF07686.12 KFM12092.1 - 5.3e-09 35.9 0.2 0.00011 22.0 0.0 3.4 3 1 0 3 3 3 2 Immunoglobulin V-set domain EF-hand_5 PF13202.1 KFM12092.1 - 2.2e-08 33.0 0.3 0.00096 18.3 0.0 2.5 2 0 0 2 2 2 2 EF hand Kazal_2 PF07648.10 KFM12092.1 - 4.6e-08 32.8 2.9 1.2e-07 31.5 2.0 1.8 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain EF-hand_1 PF00036.27 KFM12092.1 - 5.9e-08 31.4 0.1 0.00011 21.1 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 KFM12092.1 - 8.5e-08 32.2 5.4 2.1e-07 30.9 3.8 1.7 1 0 0 1 1 1 1 EF-hand domain pair Kazal_1 PF00050.16 KFM12092.1 - 2.2e-07 30.7 8.7 5.9e-07 29.4 6.0 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain EF-hand_6 PF13405.1 KFM12092.1 - 4.3e-06 26.1 0.9 0.032 14.0 0.1 3.1 3 0 0 3 3 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 KFM12092.1 - 0.00013 21.9 0.6 0.00024 21.0 0.4 1.4 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.1 KFM12092.1 - 0.00045 19.7 0.3 0.025 14.2 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair C2-set_2 PF08205.7 KFM12092.1 - 0.0048 16.7 0.0 0.33 10.8 0.0 2.7 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Cytochrom_D1 PF02239.11 KFM12092.1 - 0.013 13.8 0.5 0.093 11.0 0.1 2.3 2 1 0 2 2 2 0 Cytochrome D1 heme domain LVIVD PF08309.6 KFM12092.1 - 0.087 11.8 0.3 0.3 10.0 0.0 2.0 2 0 0 2 2 2 0 LVIVD repeat RasGEF_N PF00618.15 KFM12093.1 - 6e-19 68.0 0.4 1.6e-18 66.6 0.3 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif cNMP_binding PF00027.24 KFM12093.1 - 5.6e-13 48.5 0.0 1.1e-08 34.7 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RA PF00788.18 KFM12093.1 - 2.7e-12 47.0 0.0 8e-12 45.4 0.0 1.9 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PDZ PF00595.19 KFM12093.1 - 1.3e-11 44.4 0.0 2.7e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM12093.1 - 0.00013 21.8 0.0 0.0004 20.2 0.0 1.8 2 0 0 2 2 2 1 PDZ domain FNIP_M PF14637.1 KFM12095.1 - 2.3e-86 289.1 0.0 4.4e-86 288.2 0.0 1.5 1 0 0 1 1 1 1 Folliculin-interacting protein middle domain FNIP_C PF14638.1 KFM12095.1 - 3.8e-70 235.1 0.1 1.2e-69 233.5 0.1 1.9 2 0 0 2 2 2 1 Folliculin-interacting protein C-terminus FNIP_N PF14636.1 KFM12095.1 - 4.9e-37 127.3 0.5 2.5e-36 125.0 0.3 2.3 1 0 0 1 1 1 1 Folliculin-interacting protein N-terminus AMP-binding PF00501.23 KFM12097.1 - 2.8e-100 335.6 0.0 4.3e-100 335.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme P4Ha_N PF08336.6 KFM12099.1 - 1.1e-42 145.0 0.4 1.1e-42 145.0 0.3 2.0 2 0 0 2 2 2 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy PF03171.15 KFM12099.1 - 4.2e-12 46.2 0.0 8.8e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KFM12099.1 - 1.7e-07 31.6 0.1 5.5e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily LIM PF00412.17 KFM12100.1 - 9.3e-15 54.4 3.9 1.8e-14 53.5 2.7 1.5 1 0 0 1 1 1 1 LIM domain PDZ PF00595.19 KFM12100.1 - 1.4e-10 41.1 0.1 2.9e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM12100.1 - 0.00016 21.5 0.0 0.00032 20.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Sugar_tr PF00083.19 KFM12101.1 - 1.4e-26 93.0 19.0 2e-26 92.5 13.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFM12101.1 - 7.6e-22 77.4 58.9 3.8e-19 68.6 22.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily IRF PF00605.12 KFM12102.1 - 3e-46 155.7 1.2 5.1e-46 154.9 0.8 1.4 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor IL5 PF02025.10 KFM12103.1 - 6e-05 23.0 0.2 7.5e-05 22.7 0.2 1.2 1 0 0 1 1 1 1 Interleukin 5 RIH_assoc PF08454.6 KFM12103.1 - 0.0035 16.9 0.8 0.0054 16.3 0.5 1.2 1 0 0 1 1 1 1 RyR and IP3R Homology associated Rad50_zn_hook PF04423.9 KFM12104.1 - 1.1e-15 56.8 0.0 1.1e-15 56.8 0.0 5.7 4 0 0 4 4 4 1 Rad50 zinc hook motif SMC_N PF02463.14 KFM12104.1 - 9.1e-13 47.9 16.7 8.3e-08 31.7 3.4 3.3 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 KFM12104.1 - 2.4e-12 46.5 0.0 7.6e-12 44.9 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 KFM12104.1 - 3.7e-12 46.8 3.3 3.4e-05 23.9 0.0 3.7 2 1 1 3 3 3 2 AAA domain AAA_13 PF13166.1 KFM12104.1 - 0.00013 20.6 132.6 0.022 13.2 0.0 7.2 3 1 4 7 7 7 3 AAA domain AAA_23 PF13476.1 KFM12104.1 - 0.00057 20.2 160.6 1e+04 -3.4 20.5 9.1 2 2 1 3 3 3 0 AAA domain AAA_29 PF13555.1 KFM12104.1 - 0.0075 15.7 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_19 PF13245.1 KFM12104.1 - 0.085 12.6 0.1 0.27 11.0 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain DUF3755 PF12579.3 KFM12104.1 - 0.11 11.8 3.8 2.7 7.4 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3755) zf-C2H2_4 PF13894.1 KFM12104.1 - 0.15 12.4 0.5 0.73 10.3 0.3 2.3 1 0 0 1 1 1 0 C2H2-type zinc finger IL4 PF00727.13 KFM12105.1 - 4.2e-07 29.8 1.3 7.1e-06 25.8 0.9 2.0 1 1 0 1 1 1 1 Interleukin 4 Kinesin PF00225.18 KFM12106.1 - 1.3e-120 402.1 0.1 1.3e-120 402.1 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain AAA_22 PF13401.1 KFM12106.1 - 0.0041 17.2 3.0 1.1 9.3 0.0 2.9 2 1 0 2 2 2 2 AAA domain Cyclin_N PF00134.18 KFM12107.1 - 2.5e-22 78.8 0.4 4.5e-22 77.9 0.3 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFM12107.1 - 0.13 12.2 1.7 0.32 10.9 0.2 2.1 2 0 0 2 2 2 0 Cyclin, C-terminal domain Septin PF00735.13 KFM12108.1 - 1.6e-96 322.6 2.3 1.6e-96 322.6 1.6 2.1 2 1 0 2 2 1 1 Septin MMR_HSR1 PF01926.18 KFM12108.1 - 8.7e-06 25.6 0.0 2.2e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KFM12108.1 - 0.00061 19.8 0.7 0.0049 16.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain GTP_EFTU PF00009.22 KFM12108.1 - 0.00064 19.2 4.8 2 7.8 0.4 3.3 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KFM12108.1 - 0.001 18.2 0.1 0.0034 16.5 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KFM12108.1 - 0.0011 19.1 0.3 0.0052 16.9 0.0 2.3 3 0 0 3 3 2 1 AAA domain AAA_10 PF12846.2 KFM12108.1 - 0.0014 18.1 1.1 0.0038 16.7 0.0 2.0 2 0 0 2 2 2 1 AAA-like domain FtsK_SpoIIIE PF01580.13 KFM12108.1 - 0.0029 17.0 2.6 0.06 12.8 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family Ras PF00071.17 KFM12108.1 - 0.0058 16.0 0.9 0.015 14.7 0.0 2.1 2 0 0 2 2 2 1 Ras family ABC_tran PF00005.22 KFM12108.1 - 0.021 15.1 4.9 0.021 15.1 0.1 2.5 2 1 0 2 2 2 0 ABC transporter RNA_helicase PF00910.17 KFM12108.1 - 0.025 14.7 0.0 0.081 13.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase IMD PF08397.6 KFM12108.1 - 0.026 13.8 15.1 0.054 12.7 10.5 1.5 1 0 0 1 1 1 0 IRSp53/MIM homology domain T2SE PF00437.15 KFM12108.1 - 0.055 12.3 0.0 0.055 12.3 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein Flavi_NS1 PF00948.16 KFM12108.1 - 0.081 11.3 5.4 0.16 10.3 3.8 1.4 1 0 0 1 1 1 0 Flavivirus non-structural Protein NS1 Miro PF08477.8 KFM12108.1 - 0.097 13.1 3.0 0.099 13.1 0.1 2.6 2 2 0 2 2 2 0 Miro-like protein AAA_29 PF13555.1 KFM12108.1 - 0.13 11.8 0.1 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Exonuc_VII_L PF02601.10 KFM12108.1 - 0.22 10.6 14.8 0.41 9.7 10.3 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit FliT PF05400.8 KFM12108.1 - 0.31 11.4 9.2 0.81 10.1 6.3 1.7 1 0 0 1 1 1 0 Flagellar protein FliT AAA_32 PF13654.1 KFM12108.1 - 0.34 9.5 17.5 1.9 7.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 KFM12108.1 - 0.69 9.6 0.0 0.69 9.6 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function DUF87 DUF3287 PF11690.3 KFM12108.1 - 1.7 8.7 11.4 9.6 6.3 7.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3287) Fzo_mitofusin PF04799.8 KFM12108.1 - 2.7 7.3 10.0 1.3 8.3 5.2 1.8 2 0 0 2 2 2 0 fzo-like conserved region ATP_bind_1 PF03029.12 KFM12108.1 - 5.6 6.4 7.1 13 5.2 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_11 PF13086.1 KFM12108.1 - 7 6.1 12.5 10 5.5 8.0 1.7 1 1 0 1 1 1 0 AAA domain ASD2 PF08687.6 KFM12109.1 - 2.5e-66 223.7 14.9 2.7e-66 223.5 10.3 1.0 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 ResB PF05140.9 KFM12109.1 - 0.0027 16.3 0.2 0.0039 15.7 0.1 1.1 1 0 0 1 1 1 1 ResB-like family Oxysterol_BP PF01237.13 KFM12109.1 - 0.037 12.5 0.6 0.055 11.9 0.4 1.3 1 0 0 1 1 1 0 Oxysterol-binding protein DUF2721 PF11026.3 KFM12109.1 - 0.046 13.3 1.0 0.092 12.3 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) ING PF12998.2 KFM12109.1 - 0.23 11.7 5.5 0.51 10.6 3.7 1.7 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding AAA_23 PF13476.1 KFM12109.1 - 0.61 10.3 7.2 0.88 9.8 5.0 1.3 1 0 0 1 1 1 0 AAA domain DUF4446 PF14584.1 KFM12109.1 - 1.1 9.0 6.0 1.1 9.1 0.6 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) Syntaxin-6_N PF09177.6 KFM12109.1 - 7 7.1 11.4 14 6.1 1.7 3.0 1 1 1 3 3 3 0 Syntaxin 6, N-terminal ASD1 PF08688.5 KFM12110.1 - 3.9e-44 150.6 7.6 7.9e-44 149.6 5.2 1.5 1 0 0 1 1 1 1 Apx/Shroom domain ASD1 TGF_beta PF00019.15 KFM12111.1 - 6.6e-24 84.2 0.2 1.3e-23 83.2 0.2 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain LEAP-2 PF07359.6 KFM12112.1 - 1.3e-27 95.1 5.8 1.4e-27 95.0 4.0 1.0 1 0 0 1 1 1 1 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) EB PF01683.13 KFM12112.1 - 0.047 13.7 0.4 0.057 13.4 0.3 1.3 1 1 0 1 1 1 0 EB module AF-4 PF05110.8 KFM12113.1 - 0 1626.5 149.5 0 1626.3 103.6 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein zf-CCHC_3 PF13917.1 KFM12114.1 - 1.2e-19 69.6 3.7 2.6e-19 68.6 2.5 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF605 PF04652.11 KFM12114.1 - 0.0049 16.3 23.1 0.0057 16.0 16.0 1.0 1 0 0 1 1 1 1 Vta1 like BUD22 PF09073.5 KFM12114.1 - 0.062 12.3 41.7 0.071 12.1 28.9 1.0 1 0 0 1 1 1 0 BUD22 zf-CCHC PF00098.18 KFM12114.1 - 0.09 12.7 1.3 0.13 12.2 0.9 1.3 1 0 0 1 1 1 0 Zinc knuckle Na_trans_assoc PF06512.8 KFM12114.1 - 0.82 9.5 20.7 0.94 9.3 14.3 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated CobT PF06213.7 KFM12114.1 - 0.96 8.5 19.0 1.2 8.2 13.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF1675 PF07897.6 KFM12114.1 - 1.1 9.1 25.3 1.3 8.8 17.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) SRP-alpha_N PF04086.8 KFM12114.1 - 2.5 7.4 24.2 2.6 7.3 16.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Macoilin PF09726.4 KFM12114.1 - 3.7 5.7 36.4 3.9 5.6 25.2 1.1 1 0 0 1 1 1 0 Transmembrane protein DNA_pol_viral_N PF00242.12 KFM12114.1 - 5.1 6.0 29.0 6.2 5.7 20.1 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain HSP70 PF00012.15 KFM12115.1 - 4.8e-189 629.1 18.0 6.1e-183 608.9 0.4 3.0 1 1 2 3 3 3 3 Hsp70 protein MreB_Mbl PF06723.8 KFM12115.1 - 2.3e-10 39.5 0.0 4.1e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Ndc1_Nup PF09531.5 KFM12115.1 - 3.2 6.0 4.0 4.9 5.4 2.8 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RWD PF05773.17 KFM12116.1 - 4.8e-24 84.4 0.0 1.1e-23 83.3 0.0 1.6 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 KFM12116.1 - 7.9e-19 67.3 19.6 1e-13 50.9 2.1 4.1 3 1 0 3 3 3 2 IBR domain Glucosamine_iso PF01182.15 KFM12117.1 - 3.9e-14 52.8 0.0 6.4e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DUF2370 PF10176.4 KFM12118.1 - 1.2e-45 155.7 10.1 1.7e-35 122.4 2.6 2.9 1 1 1 2 2 2 2 Protein of unknown function (DUF2370) Herpes_UL56 PF04534.7 KFM12118.1 - 0.079 12.6 1.0 0.11 12.1 0.7 1.1 1 0 0 1 1 1 0 Herpesvirus UL56 protein DUF872 PF05915.7 KFM12118.1 - 0.21 11.4 1.2 0.4 10.5 0.5 1.7 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) DUF373 PF04123.8 KFM12118.1 - 1.1 8.2 3.0 2.4 7.1 2.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF373) TMEM52 PF14979.1 KFM12118.1 - 9.3 6.1 6.4 4.5 7.1 0.3 2.3 2 1 0 2 2 2 0 Transmembrane 52 Sprouty PF05210.8 KFM12119.1 - 4e-35 120.1 32.0 8.8e-35 119.0 22.2 1.6 1 0 0 1 1 1 1 Sprouty protein (Spry) FGF PF00167.13 KFM12121.1 - 7.8e-41 138.6 0.0 9.9e-41 138.3 0.0 1.1 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.8 KFM12121.1 - 0.00033 20.7 0.0 0.0005 20.1 0.0 1.3 1 0 0 1 1 1 1 Fascin domain Toxin_45 PF15524.1 KFM12121.1 - 0.15 12.1 0.3 3.6 7.7 0.1 2.5 1 1 0 2 2 2 0 Putative toxin 45 RhoGAP PF00620.22 KFM12122.1 - 4.4e-41 140.0 1.3 1.4e-40 138.3 0.5 2.1 2 0 0 2 2 2 1 RhoGAP domain SH3_9 PF14604.1 KFM12122.1 - 3.8e-10 39.1 0.0 7.4e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM12122.1 - 5.3e-08 32.1 0.0 1.1e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFM12122.1 - 2.6e-05 23.5 0.0 5.8e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain IMD PF08397.6 KFM12122.1 - 0.00057 19.2 4.0 0.002 17.5 2.8 1.9 1 0 0 1 1 1 1 IRSp53/MIM homology domain GCR PF02155.10 KFM12123.1 - 2.7e-174 579.2 4.3 3.4e-174 578.8 3.0 1.1 1 0 0 1 1 1 1 Glucocorticoid receptor Hormone_recep PF00104.25 KFM12123.1 - 2e-30 105.4 4.5 3e-30 104.8 3.2 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFM12123.1 - 2.3e-28 98.1 12.9 4.4e-28 97.3 9.0 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Yip1 PF04893.12 KFM12124.1 - 1.4e-10 40.9 16.1 2e-10 40.4 11.2 1.3 1 0 0 1 1 1 1 Yip1 domain DUF3488 PF11992.3 KFM12124.1 - 1.5 7.3 5.2 1.9 7.0 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) BTB_2 PF02214.17 KFM12125.1 - 6.7e-16 58.2 0.0 1.4e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain PRELI PF04707.9 KFM12126.1 - 1.3e-38 132.0 0.4 1.5e-38 131.8 0.3 1.1 1 0 0 1 1 1 1 PRELI-like family PFO_beta_C PF12367.3 KFM12126.1 - 0.013 15.4 0.0 0.036 13.9 0.0 1.7 2 0 0 2 2 2 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal DnaJ_CXXCXGXG PF00684.14 KFM12127.1 - 0.13 12.3 13.4 3.2 7.8 5.6 2.4 1 1 1 2 2 2 0 DnaJ central domain SH3_2 PF07653.12 KFM12128.1 - 3.9e-12 45.4 0.0 8.3e-12 44.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM12128.1 - 1.7e-11 43.2 0.0 3.8e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFM12128.1 - 5.6e-11 41.8 0.0 9.8e-11 41.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain zf-C3HC4_2 PF13923.1 KFM12128.1 - 5.6e-10 39.0 9.7 1.1e-09 38.1 6.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM12128.1 - 1.1e-09 37.7 10.3 2.2e-09 36.8 7.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM12128.1 - 2.1e-08 33.8 8.9 4e-08 32.9 6.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KFM12128.1 - 2.4e-08 33.5 9.2 4.5e-08 32.6 6.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFM12128.1 - 3.3e-08 33.0 6.7 6.4e-08 32.1 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFM12128.1 - 5e-08 32.5 8.5 1.4e-07 31.1 5.9 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 KFM12128.1 - 6.6e-06 25.6 7.9 1.1e-05 24.8 5.5 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 KFM12128.1 - 0.00015 21.5 10.0 0.00032 20.4 7.0 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KFM12128.1 - 0.042 13.9 4.5 0.088 12.9 3.2 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-MIZ PF02891.15 KFM12128.1 - 0.046 13.2 8.1 0.088 12.3 5.6 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-Apc11 PF12861.2 KFM12128.1 - 2.1 8.2 5.5 4.8 7.0 3.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zinc-ribbons_6 PF07191.7 KFM12128.1 - 3 7.7 8.6 5.7 6.7 6.0 1.4 1 0 0 1 1 1 0 zinc-ribbons DZR PF12773.2 KFM12128.1 - 5.4 6.9 8.6 15 5.5 6.0 1.7 1 0 0 1 1 1 0 Double zinc ribbon tRNA-synt_1 PF00133.17 KFM12129.1 - 3e-38 131.2 0.0 8.3e-25 86.8 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KFM12129.1 - 1.6e-20 73.1 0.1 2.4e-10 39.6 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KFM12129.1 - 1.6e-16 60.4 0.0 4.1e-16 59.1 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 KFM12129.1 - 1.8e-06 27.2 0.0 3.5e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain RRM_5 PF13893.1 KFM12130.1 - 9.2e-17 60.6 0.0 6.9e-09 35.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM12130.1 - 2.2e-11 43.5 0.1 1.6e-08 34.3 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFM12130.1 - 8.7e-11 41.4 0.0 3.8e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.17 KFM12130.1 - 4.7e-10 38.9 0.7 8.6e-05 22.1 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 KFM12130.1 - 1.2e-05 24.9 0.5 0.061 13.0 0.0 3.2 2 2 0 2 2 2 2 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 KFM12130.1 - 3.9e-05 23.2 1.0 7e-05 22.4 0.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PWI PF01480.12 KFM12130.1 - 0.0059 16.6 0.0 0.02 15.0 0.0 1.9 1 0 0 1 1 1 1 PWI domain DUF342 PF03961.8 KFM12130.1 - 0.19 10.0 10.1 0.34 9.2 7.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) FF PF01846.14 KFM12131.1 - 4.1e-79 260.3 45.3 1.7e-14 53.4 1.0 6.6 6 0 0 6 6 6 6 FF domain WW PF00397.21 KFM12131.1 - 1.5e-17 63.0 27.3 4.4e-07 29.6 3.9 3.9 4 0 0 4 4 4 3 WW domain WD40 PF00400.27 KFM12132.1 - 1.5e-15 56.3 1.8 0.54 10.2 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Pkinase PF00069.20 KFM12133.1 - 4.4e-62 209.5 0.1 4.4e-62 209.5 0.1 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM12133.1 - 1.3e-38 132.5 0.1 1.7e-38 132.1 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM12133.1 - 1.5e-13 50.4 0.0 1.9e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFM12133.1 - 0.0031 17.2 0.4 0.0049 16.6 0.3 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DDE_Tnp_4 PF13359.1 KFM12133.1 - 0.023 14.2 0.3 0.053 13.1 0.2 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease Amidohydro_1 PF01979.15 KFM12134.1 - 5.6e-36 124.8 0.0 7.5e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KFM12134.1 - 2.8e-16 60.3 0.0 4e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KFM12134.1 - 5e-11 42.2 3.6 5.4e-11 42.1 0.8 2.4 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 KFM12134.1 - 5.7e-07 29.1 0.1 0.0083 15.3 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_2 PF04909.9 KFM12134.1 - 2.7e-06 27.1 0.1 1.3e-05 24.9 0.1 2.1 3 0 0 3 3 3 1 Amidohydrolase Pox_A_type_inc PF04508.7 KFM12135.1 - 0.059 13.1 0.0 0.059 13.1 0.0 9.7 13 1 0 13 13 13 0 Viral A-type inclusion protein repeat APC8 PF04049.8 KFM12136.1 - 7.7e-29 100.2 3.7 7.7e-29 100.2 2.6 2.9 3 1 1 4 4 4 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 KFM12136.1 - 6.5e-28 95.1 36.7 5.4e-06 25.7 0.1 10.2 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.12 KFM12136.1 - 1.1e-25 87.3 37.6 0.00044 19.9 0.1 10.5 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_11 PF13414.1 KFM12136.1 - 2.7e-20 71.7 31.6 5.3e-08 32.4 0.6 7.8 5 1 3 8 8 8 6 TPR repeat TPR_8 PF13181.1 KFM12136.1 - 3.7e-17 60.7 31.2 0.00026 20.5 0.0 10.1 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_14 PF13428.1 KFM12136.1 - 8.9e-16 56.9 16.2 0.0086 16.6 0.0 9.7 8 2 2 10 10 10 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFM12136.1 - 1.5e-13 50.4 32.0 0.0025 17.7 1.4 8.7 4 2 6 10 10 10 6 Tetratricopeptide repeat TPR_7 PF13176.1 KFM12136.1 - 1.3e-12 46.5 22.5 0.02 14.6 0.1 9.1 9 1 0 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 KFM12136.1 - 8.2e-10 39.0 19.4 0.00026 21.5 0.0 7.8 5 3 2 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFM12136.1 - 3.7e-09 36.7 20.7 0.0079 16.5 0.1 7.2 7 1 0 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFM12136.1 - 7.3e-09 35.1 17.4 0.043 14.0 0.0 7.5 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_6 PF13174.1 KFM12136.1 - 1.3e-06 28.4 33.7 1.2 9.7 0.0 10.6 12 0 0 12 12 11 2 Tetratricopeptide repeat Apc3 PF12895.2 KFM12136.1 - 1.3e-05 25.2 39.6 0.021 14.9 0.8 6.7 4 2 5 9 9 9 5 Anaphase-promoting complex, cyclosome, subunit 3 DUF772 PF05598.6 KFM12136.1 - 0.00017 21.3 0.0 0.00048 19.9 0.0 1.7 1 0 0 1 1 1 1 Transposase domain (DUF772) TPR_10 PF13374.1 KFM12136.1 - 0.00023 20.9 10.0 2.7 8.0 0.0 6.8 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFM12136.1 - 0.0069 16.2 7.4 0.068 13.0 0.1 4.1 3 1 0 4 4 4 1 Tetratricopeptide repeat PPR PF01535.15 KFM12136.1 - 0.14 12.2 1.7 11 6.2 0.0 4.4 5 0 0 5 5 5 0 PPR repeat GDNF PF02351.11 KFM12137.1 - 8.2e-34 115.9 42.6 7.9e-18 64.7 6.2 3.2 3 0 0 3 3 3 3 GDNF/GAS1 domain 2-Hacid_dh_C PF02826.14 KFM12138.1 - 1.6e-56 190.3 0.0 2.2e-56 189.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFM12138.1 - 1.5e-26 92.4 0.0 1.8e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KFM12138.1 - 6.2e-05 22.9 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KFM12138.1 - 0.037 14.4 0.0 0.67 10.4 0.0 2.6 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent XdhC_C PF13478.1 KFM12138.1 - 0.06 13.6 0.0 0.19 12.0 0.0 1.9 1 0 0 1 1 1 0 XdhC Rossmann domain TB2_DP1_HVA22 PF03134.14 KFM12139.1 - 1.4e-31 108.0 10.0 1.8e-31 107.6 7.0 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF3432 PF11914.3 KFM12140.1 - 8.1e-38 128.4 37.9 8.1e-38 128.4 26.3 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF3432) DUF3446 PF11928.3 KFM12140.1 - 1.4e-29 102.0 15.5 1.4e-29 102.0 10.7 4.3 3 1 1 4 4 2 1 Domain of unknown function (DUF3446) zf-H2C2_2 PF13465.1 KFM12140.1 - 2.2e-18 65.5 19.3 7.1e-09 35.5 0.5 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 KFM12140.1 - 2e-15 56.1 15.6 1.4e-05 25.1 0.2 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM12140.1 - 1.1e-13 50.4 13.7 0.0003 20.9 0.2 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KFM12140.1 - 0.0018 17.8 8.8 0.11 12.2 0.3 3.4 3 0 0 3 3 3 1 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 KFM12140.1 - 0.0022 18.0 4.0 4.7 7.4 0.0 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding RRN7 PF11781.3 KFM12140.1 - 0.017 14.5 7.1 0.11 11.9 0.1 3.1 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-BED PF02892.10 KFM12140.1 - 0.021 14.5 9.2 0.062 13.0 2.8 2.8 1 1 2 3 3 3 0 BED zinc finger zf-C2H2_6 PF13912.1 KFM12140.1 - 0.021 14.7 7.6 1.8 8.6 0.5 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.2 KFM12140.1 - 0.17 12.1 5.5 17 5.7 0.5 3.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type C1_2 PF03107.11 KFM12140.1 - 0.29 11.2 2.4 8.4 6.6 0.1 2.5 2 0 0 2 2 2 0 C1 domain zf-UBR PF02207.15 KFM12140.1 - 0.43 10.3 3.7 0.71 9.6 2.5 1.3 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) 2OG-FeII_Oxy PF03171.15 KFM12141.1 - 1.1e-10 41.6 0.0 1.9e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily P4Ha_N PF08336.6 KFM12141.1 - 1.5e-09 37.7 0.0 3.8e-09 36.4 0.0 1.6 2 0 0 2 2 2 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.1 KFM12141.1 - 2.4e-07 31.1 0.1 6e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_2 PF07719.12 KFM12141.1 - 0.0026 17.5 0.3 1.9 8.5 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFM12141.1 - 0.07 13.0 0.1 0.37 10.7 0.1 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 KFM12142.1 - 1.7e-29 103.3 0.0 5.3e-29 101.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFM12142.1 - 6.9e-12 45.3 0.0 1.1e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFM12142.1 - 8.2e-11 41.8 0.0 1e-06 28.4 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Thioesterase PF00975.15 KFM12142.1 - 0.00036 20.8 0.0 0.00068 19.9 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.8 KFM12142.1 - 0.0004 20.0 0.0 0.00063 19.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 KFM12142.1 - 0.0013 18.2 0.0 0.0061 16.0 0.0 1.9 1 1 0 1 1 1 1 Putative esterase PGAP1 PF07819.8 KFM12142.1 - 0.0019 17.8 0.1 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 KFM12142.1 - 0.004 16.7 0.0 0.015 14.9 0.0 1.7 1 1 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.3 KFM12142.1 - 0.0059 16.4 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 KFM12142.1 - 0.01 15.3 1.7 1.3 8.4 0.1 2.7 2 1 0 3 3 3 0 Phospholipase/Carboxylesterase DUF2974 PF11187.3 KFM12142.1 - 0.15 11.3 0.0 0.28 10.5 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) CTDII PF01556.13 KFM12143.1 - 6.8e-22 77.1 0.4 1.7e-18 66.2 0.0 2.6 2 1 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 KFM12143.1 - 7.4e-21 73.6 0.4 1.4e-20 72.7 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain WD40 PF00400.27 KFM12144.1 - 6.5e-29 98.7 10.4 3.1e-08 33.2 0.2 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat CHCH PF06747.8 KFM12145.1 - 1.4e-05 24.8 3.4 1.9e-05 24.4 2.4 1.2 1 0 0 1 1 1 1 CHCH domain COX17 PF05051.8 KFM12145.1 - 0.015 15.2 2.0 0.026 14.5 1.4 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Pet191_N PF10203.4 KFM12145.1 - 0.02 14.8 0.6 0.024 14.6 0.4 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 KFM12145.1 - 0.027 14.2 3.1 2.7 7.8 0.0 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like DB PF01682.14 KFM12145.1 - 0.071 13.1 0.9 0.085 12.8 0.6 1.1 1 0 0 1 1 1 0 DB module Ribosomal_S10 PF00338.17 KFM12146.1 - 3.1e-14 52.5 0.6 4.4e-14 52.0 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e Ras PF00071.17 KFM12147.1 - 1.4e-53 180.5 1.3 1.7e-53 180.3 0.9 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM12147.1 - 1.7e-18 67.2 0.2 3.5e-18 66.2 0.1 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFM12147.1 - 4.7e-12 45.4 0.7 5.5e-12 45.2 0.5 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFM12147.1 - 1.6e-06 27.7 0.3 2.5e-06 27.0 0.2 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KFM12147.1 - 0.00034 19.8 0.1 0.00044 19.5 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KFM12147.1 - 0.0029 17.5 0.1 0.0043 17.0 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFM12147.1 - 0.0088 15.1 0.3 0.0099 15.0 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 KFM12147.1 - 0.0096 15.2 0.3 0.011 14.9 0.2 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF1854 PF08909.6 KFM12147.1 - 0.062 12.9 0.1 0.082 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1854) PH PF00169.24 KFM12148.1 - 1.1e-09 38.3 0.0 1.6e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KFM12148.1 - 1.2e-06 28.6 1.5 1.8e-06 28.1 1.0 1.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 KFM12148.1 - 0.00059 19.8 0.1 0.01 15.8 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain TCRP1 PF14944.1 KFM12149.1 - 1.7e-93 311.9 41.3 2.1e-93 311.7 28.6 1.1 1 0 0 1 1 1 1 Tongue Cancer Chemotherapy Resistant Protein 1 RhoGEF PF00621.15 KFM12151.1 - 6.8e-44 149.8 3.6 1.1e-43 149.2 2.5 1.3 1 0 0 1 1 1 1 RhoGEF domain BBS2_Mid PF14783.1 KFM12151.1 - 0.0054 16.4 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, middle region UPF0278 PF08745.6 KFM12151.1 - 0.018 14.3 0.2 0.038 13.2 0.1 1.4 1 0 0 1 1 1 0 UPF0278 family SH3_1 PF00018.23 KFM12152.1 - 2.7e-26 90.7 1.5 1.4e-12 46.8 0.1 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 KFM12152.1 - 1.1e-24 85.7 1.5 8e-14 50.9 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 KFM12152.1 - 3.3e-21 74.5 0.2 1e-10 40.9 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.18 KFM12152.1 - 1e-05 25.6 0.2 1e-05 25.6 0.1 3.3 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_3 PF08239.6 KFM12152.1 - 0.0044 17.1 0.5 0.014 15.5 0.0 2.0 2 0 0 2 2 2 1 Bacterial SH3 domain Toxin_52 PF15605.1 KFM12152.1 - 0.068 13.0 1.3 8.6 6.3 0.1 3.5 3 1 0 3 3 3 0 Putative toxin 52 Vac14_Fab1_bd PF12755.2 KFM12152.1 - 0.082 13.3 1.1 0.23 11.8 0.2 2.1 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region hSH3 PF14603.1 KFM12152.1 - 0.11 12.4 0.2 0.68 9.9 0.0 2.2 2 0 0 2 2 2 0 Helically-extended SH3 domain H-kinase_dim PF02895.9 KFM12152.1 - 0.45 10.8 3.3 21 5.5 0.0 3.6 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Gp-FAR-1 PF05823.7 KFM12152.1 - 0.63 9.9 7.6 0.074 13.0 0.8 2.3 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Ribosomal_S3_C PF00189.15 KFM12153.1 - 2.2e-16 59.8 0.1 4e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 KFM12153.1 - 5.9e-12 44.9 0.1 9.2e-12 44.3 0.1 1.3 1 0 0 1 1 1 1 KH domain RVT_1 PF00078.22 KFM12154.1 - 0.043 13.1 0.0 0.078 12.3 0.0 1.4 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) GDPD PF03009.12 KFM12155.1 - 1.2e-21 77.3 0.0 1.5e-19 70.4 0.0 2.3 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family Kelch_1 PF01344.20 KFM12156.1 - 4.4e-58 192.6 2.4 3.2e-12 45.7 0.0 6.7 6 1 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 KFM12156.1 - 3e-39 131.5 9.2 4.7e-09 36.0 0.0 6.5 4 1 2 6 6 6 5 Kelch motif BACK PF07707.10 KFM12156.1 - 1.6e-32 111.4 0.3 6.6e-32 109.4 0.2 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.26 KFM12156.1 - 4.7e-30 103.8 0.1 1.3e-29 102.3 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.10 KFM12156.1 - 3.2e-29 99.5 6.5 5e-05 22.8 0.0 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.1 KFM12156.1 - 8.6e-28 95.8 6.4 5.2e-05 22.9 0.0 7.0 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 KFM12156.1 - 2.3e-25 88.0 2.9 0.0034 17.4 0.0 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 KFM12156.1 - 3.6e-15 55.5 11.7 0.014 15.2 0.1 6.1 6 0 0 6 6 6 4 Kelch motif DUF3342 PF11822.3 KFM12156.1 - 4.1e-05 22.8 0.0 9.9e-05 21.6 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) Pput2613-deam PF14427.1 KFM12156.1 - 0.16 11.6 0.0 4.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Pput_2613-like deaminase STOP PF05217.7 KFM12157.1 - 1e-09 38.4 7.3 2.9e-07 30.4 0.7 2.4 2 0 0 2 2 2 2 STOP protein Clr5 PF14420.1 KFM12157.1 - 0.8 9.6 2.8 1 9.2 0.3 2.3 2 0 0 2 2 2 0 Clr5 domain DAGAT PF03982.8 KFM12158.1 - 2.7e-118 393.9 0.0 3.2e-118 393.7 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.16 KFM12158.1 - 0.0039 16.6 0.0 0.02 14.3 0.0 2.1 2 0 0 2 2 2 1 Acyltransferase DAGAT PF03982.8 KFM12159.1 - 5.2e-143 475.1 0.0 6.4e-143 474.8 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.16 KFM12159.1 - 0.0032 16.9 0.0 0.0061 15.9 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Atg14 PF10186.4 KFM12160.1 - 4.3e-22 78.4 8.8 6.6e-22 77.8 6.1 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 KFM12160.1 - 3.4e-07 29.6 6.0 6e-07 28.8 4.1 1.3 1 0 0 1 1 1 1 Autophagy protein Apg6 C2 PF00168.25 KFM12160.1 - 0.0012 18.6 0.0 0.0027 17.5 0.0 1.6 1 0 0 1 1 1 1 C2 domain TPR_MLP1_2 PF07926.7 KFM12160.1 - 0.18 11.5 12.4 0.41 10.4 8.6 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.14 KFM12160.1 - 1.5 6.5 6.8 2.1 6.0 4.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 KFM12160.1 - 2.3 6.5 11.2 3.5 5.9 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 KFM12160.1 - 8.1 5.9 18.4 19 4.8 12.7 1.5 1 0 0 1 1 1 0 IncA protein wnt PF00110.14 KFM12161.1 - 3.6e-106 354.8 17.7 4.1e-106 354.6 12.3 1.0 1 0 0 1 1 1 1 wnt family DUF4371 PF14291.1 KFM12162.1 - 1.8e-16 60.4 0.1 4.8e-16 59.0 0.0 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4371) Dimer_Tnp_hAT PF05699.9 KFM12162.1 - 6.4e-10 38.5 0.0 1.4e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region THAP PF05485.7 KFM12162.1 - 1.1e-08 35.1 0.3 2.6e-08 33.9 0.2 1.7 1 0 0 1 1 1 1 THAP domain ENT PF03735.9 KFM12163.1 - 3.8e-24 84.2 0.1 7.7e-24 83.2 0.1 1.6 1 0 0 1 1 1 1 ENT domain Guanylate_cyc PF00211.15 KFM12164.1 - 3.9e-65 218.6 0.1 1.4e-64 216.8 0.0 2.0 3 0 0 3 3 3 1 Adenylate and Guanylate cyclase catalytic domain ANF_receptor PF01094.23 KFM12164.1 - 5e-50 170.2 0.0 7.6e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase_Tyr PF07714.12 KFM12164.1 - 1e-37 129.6 0.0 1.6e-37 129.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM12164.1 - 9.9e-29 100.2 0.0 1.6e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.9 KFM12164.1 - 1.1e-05 24.8 0.7 1.7e-05 24.1 0.5 1.3 1 0 0 1 1 1 1 Heme NO binding associated Kinase-like PF14531.1 KFM12164.1 - 0.027 13.4 0.0 0.055 12.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like LRR_8 PF13855.1 KFM12166.1 - 3.1e-55 183.7 67.4 1.7e-11 43.6 2.1 6.3 1 1 7 9 9 9 9 Leucine rich repeat LRR_4 PF12799.2 KFM12166.1 - 3.7e-26 90.2 66.0 2.1e-07 30.4 0.6 6.9 2 2 7 9 9 9 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM12166.1 - 1.6e-25 85.2 28.9 0.0031 17.3 0.2 10.5 9 1 1 10 10 10 7 Leucine Rich Repeat LRR_5 PF13306.1 KFM12166.1 - 6.8e-12 45.2 0.2 6.2e-05 22.7 0.2 2.5 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) LRR_7 PF13504.1 KFM12166.1 - 3.6e-11 41.3 30.2 0.13 12.5 0.2 9.6 10 0 0 10 10 10 4 Leucine rich repeat LRR_6 PF13516.1 KFM12166.1 - 5.5e-10 38.2 34.0 0.45 10.7 0.2 10.2 9 2 2 11 11 11 5 Leucine Rich repeat LRRNT PF01462.13 KFM12166.1 - 0.045 13.2 0.7 0.19 11.2 0.5 2.1 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain Ceramidase PF05875.7 KFM12167.1 - 2.4e-84 282.5 17.9 2.9e-84 282.2 12.4 1.0 1 0 0 1 1 1 1 Ceramidase Peptidase_C2 PF00648.16 KFM12168.1 - 5.4e-111 370.3 1.3 7.6e-111 369.8 0.9 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 KFM12168.1 - 2.4e-45 153.7 0.0 3.8e-45 153.1 0.0 1.3 1 0 0 1 1 1 1 Calpain large subunit, domain III C2 PF00168.25 KFM12168.1 - 2.4e-14 52.9 0.0 5.6e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 C2 domain Myosin_head PF00063.16 KFM12169.1 - 1.1e-230 767.3 1.7 1.7e-230 766.7 1.2 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) MyTH4 PF00784.12 KFM12169.1 - 1.7e-76 253.5 0.0 7.3e-37 125.8 0.0 3.0 2 0 0 2 2 2 2 MyTH4 domain FERM_M PF00373.13 KFM12169.1 - 1.2e-21 77.2 6.8 3.6e-16 59.4 0.0 4.2 4 0 0 4 4 3 2 FERM central domain IQ PF00612.22 KFM12169.1 - 2e-16 57.9 23.2 0.00011 21.5 0.1 5.9 5 0 0 5 5 5 4 IQ calmodulin-binding motif FERM_N PF09379.5 KFM12169.1 - 2e-10 40.5 0.2 0.00019 21.4 0.0 2.7 2 0 0 2 2 2 2 FERM N-terminal domain RA PF00788.18 KFM12169.1 - 0.002 18.5 0.0 0.67 10.4 0.0 2.9 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain AAA_16 PF13191.1 KFM12169.1 - 0.0097 15.9 0.7 0.11 12.5 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain PID PF00640.18 KFM12169.1 - 0.022 14.7 0.0 0.071 13.0 0.0 1.8 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) AAA_22 PF13401.1 KFM12169.1 - 0.023 14.8 0.0 0.32 11.1 0.0 3.0 2 1 1 3 3 3 0 AAA domain SH3_9 PF14604.1 KFM12169.1 - 0.036 13.6 0.0 0.16 11.5 0.0 2.2 1 0 0 1 1 1 0 Variant SH3 domain DUF3752 PF12572.3 KFM12169.1 - 0.037 14.1 10.2 0.1 12.7 7.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) ABC_tran PF00005.22 KFM12169.1 - 0.22 11.8 2.3 0.27 11.5 0.0 2.2 2 0 0 2 2 2 0 ABC transporter GDPD PF03009.12 KFM12170.1 - 4e-17 62.5 0.0 5.5e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Pkinase PF00069.20 KFM12171.1 - 2e-63 213.9 0.0 4.8e-63 212.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM12171.1 - 1.8e-42 145.1 0.0 2.9e-42 144.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 KFM12171.1 - 2.5e-24 85.4 0.4 1e-23 83.4 0.0 2.2 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 KFM12171.1 - 2.4e-08 33.3 0.0 6.9e-05 21.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KFM12171.1 - 0.0015 18.2 0.0 0.022 14.5 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family DSHCT PF08148.7 KFM12171.1 - 0.004 16.4 0.0 0.0084 15.3 0.0 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain Kdo PF06293.9 KFM12171.1 - 0.1 11.6 0.0 0.23 10.4 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family MIP PF00230.15 KFM12172.1 - 1.4e-09 37.7 5.1 1.4e-09 37.7 3.5 2.0 1 1 1 2 2 2 2 Major intrinsic protein Voldacs PF03517.8 KFM12173.1 - 2.6e-33 114.7 2.5 3.7e-33 114.2 1.7 1.1 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling WHIM3 PF15614.1 KFM12174.1 - 4.1e-21 74.5 0.0 1.7e-20 72.4 0.0 2.2 1 1 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 PHD PF00628.24 KFM12174.1 - 4.8e-10 38.9 4.4 1.8e-09 37.1 3.1 2.1 1 0 0 1 1 1 1 PHD-finger WHIM1 PF15612.1 KFM12174.1 - 7e-07 28.8 0.1 2e-06 27.4 0.1 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM2 PF15613.1 KFM12174.1 - 1.8e-05 24.4 0.3 5.1e-05 23.0 0.2 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 Prok-RING_1 PF14446.1 KFM12174.1 - 0.0062 16.2 1.2 0.016 14.9 0.8 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 PHD_2 PF13831.1 KFM12174.1 - 0.059 12.6 4.6 0.063 12.6 0.1 3.1 3 0 0 3 3 3 0 PHD-finger DUF498 PF04430.9 KFM12175.1 - 1.3e-23 82.6 0.0 1.5e-23 82.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) HEAT PF02985.17 KFM12176.1 - 7.3e-26 87.9 5.4 0.00074 19.3 0.0 8.7 8 0 0 8 8 8 5 HEAT repeat HEAT_2 PF13646.1 KFM12176.1 - 3.7e-21 75.1 2.6 1e-06 28.9 0.1 5.8 2 2 2 5 5 5 4 HEAT repeats Adaptin_N PF01602.15 KFM12176.1 - 4.9e-11 41.6 3.2 0.00024 19.5 0.1 3.3 2 1 1 3 3 3 3 Adaptin N terminal region Cnd1 PF12717.2 KFM12176.1 - 2.7e-10 40.3 1.4 9.1e-06 25.6 0.2 3.0 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 KFM12176.1 - 6e-08 32.9 2.3 0.0002 21.6 0.1 4.5 3 2 2 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KFM12176.1 - 3.1e-07 30.6 7.7 0.13 12.7 0.3 6.7 7 1 1 8 8 8 2 HEAT-like repeat CLASP_N PF12348.3 KFM12176.1 - 1e-05 25.0 0.6 2.2 7.5 0.1 4.3 2 2 3 5 5 5 3 CLASP N terminal Cohesin_HEAT PF12765.2 KFM12176.1 - 6.7e-05 22.7 0.0 0.41 10.6 0.0 4.2 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion DUF445 PF04286.7 KFM12176.1 - 0.0013 18.3 2.7 0.11 11.9 0.0 2.8 2 1 0 3 3 3 2 Protein of unknown function (DUF445) Cnd3 PF12719.2 KFM12176.1 - 0.0021 17.0 1.2 0.67 8.8 0.0 3.0 2 1 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain API5 PF05918.6 KFM12176.1 - 0.051 12.0 0.1 0.22 9.9 0.0 2.0 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) HEAT_PBS PF03130.11 KFM12176.1 - 0.096 13.2 0.6 34 5.3 0.0 4.7 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat BTB_2 PF02214.17 KFM12177.1 - 3.8e-17 62.2 0.0 6e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain INT_SG_DDX_CT_C PF15300.1 KFM12177.1 - 0.076 12.4 0.2 0.41 10.1 0.0 2.4 3 1 0 3 3 3 0 INTS6/SAGE1/DDX26B/CT45 C-terminus Spot_14 PF07084.7 KFM12178.1 - 3.1e-14 53.1 0.2 8.9e-14 51.6 0.1 1.6 1 1 0 1 1 1 1 Thyroid hormone-inducible hepatic protein Spot 14 NDUF_C2 PF06374.6 KFM12179.1 - 5.3e-22 78.0 0.2 5.8e-22 77.8 0.1 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) Alg6_Alg8 PF03155.10 KFM12180.1 - 2.7e-161 537.5 30.2 3.1e-161 537.3 20.9 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family BTB_2 PF02214.17 KFM12181.1 - 1e-21 76.9 0.0 2.1e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KFM12181.1 - 0.032 14.2 0.0 0.078 12.9 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain UCH PF00443.24 KFM12182.1 - 2.6e-49 167.7 0.0 4.9e-49 166.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFM12182.1 - 2.3e-29 102.7 0.0 5.3e-29 101.5 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase PH PF00169.24 KFM12183.1 - 2.3e-15 56.6 2.0 2.5e-14 53.3 0.1 2.9 3 0 0 3 3 3 1 PH domain PH_11 PF15413.1 KFM12183.1 - 3.3e-07 30.5 1.3 3.5e-06 27.2 0.9 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 KFM12183.1 - 0.056 13.3 0.4 0.22 11.4 0.3 2.0 1 1 0 1 1 1 0 PH domain tRNA-synt_2 PF00152.15 KFM12184.1 - 1.1e-75 254.5 0.0 1.3e-75 254.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KFM12184.1 - 6e-11 42.0 0.1 9.8e-11 41.3 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KFM12184.1 - 0.00012 21.3 2.5 0.29 10.3 0.0 2.9 3 1 0 3 3 3 2 tRNA synthetases class II core domain (F) Ten_N PF06484.7 KFM12187.1 - 1.3e-32 113.4 11.1 1.8e-32 112.8 7.7 1.3 1 0 0 1 1 1 1 Teneurin Intracellular Region Tox-GHH PF15636.1 KFM12187.1 - 1.2e-31 108.2 0.8 2.1e-31 107.3 0.5 1.5 1 0 0 1 1 1 1 GHH signature containing HNH/Endo VII superfamily nuclease toxin EGF_2 PF07974.8 KFM12187.1 - 8.5e-19 67.4 157.5 0.00025 21.1 9.2 9.6 9 0 0 9 9 9 8 EGF-like domain NHL PF01436.16 KFM12187.1 - 1.1e-13 50.4 1.6 0.0026 17.6 0.0 7.1 6 0 0 6 6 6 3 NHL repeat RHS_repeat PF05593.9 KFM12187.1 - 1e-10 41.4 33.6 0.0014 18.7 0.0 9.4 8 1 2 10 10 10 5 RHS Repeat hEGF PF12661.2 KFM12187.1 - 0.00012 21.9 77.4 0.025 14.6 2.5 9.3 8 0 0 8 8 8 6 Human growth factor-like EGF RHS PF03527.9 KFM12187.1 - 0.00037 20.1 0.0 0.088 12.5 0.0 2.9 2 0 0 2 2 2 1 RHS protein CarboxypepD_reg PF13620.1 KFM12187.1 - 0.004 17.1 1.7 0.012 15.7 0.0 2.6 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain Ten_N PF06484.7 KFM12188.1 - 1.1e-34 120.2 7.5 1.2e-34 120.0 5.2 1.0 1 0 0 1 1 1 1 Teneurin Intracellular Region RVT_1 PF00078.22 KFM12189.1 - 0.014 14.7 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Yae1_N PF09811.4 KFM12190.1 - 2.5e-06 26.9 47.7 1.5e+04 -20.2 33.1 5.9 1 1 0 1 1 1 0 Essential protein Yae1, N terminal MSV199 PF10553.4 KFM12193.1 - 0.022 14.6 0.2 0.027 14.3 0.1 1.1 1 0 0 1 1 1 0 MSV199 domain BAR PF03114.13 KFM12193.1 - 0.026 14.0 0.0 0.031 13.7 0.0 1.1 1 0 0 1 1 1 0 BAR domain SH3_1 PF00018.23 KFM12194.1 - 4.4e-16 57.9 0.0 3.4e-13 48.7 0.0 2.3 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 KFM12194.1 - 2.3e-12 46.2 0.0 5e-12 45.1 0.0 1.5 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 KFM12194.1 - 7.4e-12 44.6 0.1 3.2e-10 39.4 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain Metallophos PF00149.23 KFM12195.1 - 2.5e-39 134.7 0.5 4e-39 134.0 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Zip PF02535.17 KFM12196.1 - 2.6e-47 161.3 2.3 3e-47 161.1 1.6 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Piwi PF02171.12 KFM12197.1 - 2e-81 273.2 0.1 2.6e-81 272.8 0.1 1.1 1 0 0 1 1 1 1 Piwi domain fn3 PF00041.16 KFM12198.1 - 0.04 14.0 0.0 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 Fibronectin type III domain EPTP PF03736.12 KFM12199.1 - 5.2e-89 291.7 15.1 1.3e-14 53.6 0.1 7.4 7 0 0 7 7 7 7 EPTP domain LRR_8 PF13855.1 KFM12199.1 - 3.1e-21 74.8 10.1 2.9e-12 46.1 3.2 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 KFM12199.1 - 4.7e-09 35.6 6.6 0.00068 19.2 1.2 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFM12199.1 - 9.7e-09 35.0 0.0 2e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_1 PF00560.28 KFM12199.1 - 3e-07 29.5 8.2 0.016 15.1 0.4 4.8 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_9 PF14580.1 KFM12199.1 - 0.00035 20.1 0.1 0.00063 19.3 0.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeat Pectate_lyase_2 PF06917.7 KFM12199.1 - 0.016 13.5 0.1 0.14 10.3 0.0 2.0 2 0 0 2 2 2 0 Periplasmic pectate lyase LRR_7 PF13504.1 KFM12199.1 - 0.027 14.6 10.9 0.49 10.8 0.6 4.7 4 0 0 4 4 4 0 Leucine rich repeat DBP10CT PF08147.7 KFM12199.1 - 0.19 11.5 1.1 9.1 6.1 0.1 3.0 4 0 0 4 4 4 0 DBP10CT (NUC160) domain TB2_DP1_HVA22 PF03134.14 KFM12200.1 - 5.4e-30 102.9 8.8 7e-30 102.6 6.1 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Baculo_ODV-E27 PF05314.6 KFM12200.1 - 0.2 10.7 0.5 0.31 10.0 0.4 1.3 1 0 0 1 1 1 0 Baculovirus occlusion-derived virus envelope protein EC27 DUF2306 PF10067.4 KFM12200.1 - 2.1 8.5 5.8 0.32 11.1 0.6 2.1 2 1 1 3 3 3 0 Predicted membrane protein (DUF2306) PH PF00169.24 KFM12201.1 - 9.7e-07 28.9 0.0 1e-06 28.8 0.0 1.0 1 0 0 1 1 1 1 PH domain FGF PF00167.13 KFM12202.1 - 8.6e-37 125.6 0.9 1.2e-36 125.1 0.6 1.1 1 0 0 1 1 1 1 Fibroblast growth factor IL1 PF00340.14 KFM12202.1 - 0.017 14.6 0.1 0.039 13.4 0.0 1.5 1 1 0 1 1 1 0 Interleukin-1 / 18 Fascin PF06268.8 KFM12202.1 - 0.061 13.4 0.1 0.084 12.9 0.0 1.3 1 0 0 1 1 1 0 Fascin domain Polysacc_synt_4 PF04669.8 KFM12203.1 - 0.029 13.7 0.0 0.03 13.7 0.0 1.0 1 0 0 1 1 1 0 Polysaccharide biosynthesis IBN_N PF03810.14 KFM12204.1 - 1.6e-11 43.9 0.3 1.3e-10 41.0 0.0 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain CRM1_C PF08767.6 KFM12204.1 - 0.00055 18.9 0.4 0.0018 17.2 0.2 1.9 1 0 0 1 1 1 1 CRM1 C terminal GDNF PF02351.11 KFM12206.1 - 9.2e-46 154.2 46.6 5.7e-21 74.8 4.6 3.1 3 0 0 3 3 3 3 GDNF/GAS1 domain ATP-synt_ab PF00006.20 KFM12207.1 - 7.3e-62 208.6 0.0 9.7e-62 208.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KFM12207.1 - 9e-17 61.5 0.0 1.9e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KFM12207.1 - 6.5e-12 45.4 0.4 1.6e-11 44.2 0.1 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 KFM12207.1 - 0.013 15.3 0.1 0.025 14.4 0.1 1.5 1 0 0 1 1 1 0 HAS barrel domain MFS_1 PF07690.11 KFM12208.1 - 1.1e-38 132.9 45.1 1.2e-32 113.0 25.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFM12208.1 - 6.6e-11 41.4 24.0 6.9e-11 41.3 3.0 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Mak16 PF04874.9 KFM12209.1 - 6.8e-29 99.9 15.9 6.8e-29 99.9 11.0 2.8 2 1 1 3 3 3 1 Mak16 protein C-terminal region Ribosomal_L28e PF01778.12 KFM12209.1 - 4.3e-25 88.3 0.0 7.8e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L28e protein family Nop14 PF04147.7 KFM12209.1 - 0.0024 15.8 21.2 0.003 15.5 14.7 1.1 1 0 0 1 1 1 1 Nop14-like family Na_trans_assoc PF06512.8 KFM12209.1 - 0.078 12.9 11.1 0.096 12.6 7.7 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated DUF2201_N PF13203.1 KFM12209.1 - 0.17 10.9 6.8 0.25 10.4 4.7 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain GCP5-Mod21 PF14609.1 KFM12209.1 - 0.43 8.6 9.6 0.57 8.2 6.6 1.1 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 Hid1 PF12722.2 KFM12209.1 - 1.1 6.8 7.8 1.2 6.6 5.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1510 PF07423.6 KFM12209.1 - 1.5 8.1 15.5 2.5 7.4 10.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2454 PF10521.4 KFM12210.1 - 0.0098 14.9 0.0 0.069 12.1 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2454) zf-RING_2 PF13639.1 KFM12211.1 - 1.9e-12 46.7 9.0 4.4e-12 45.6 6.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KFM12211.1 - 5.4e-08 32.3 7.8 1.4e-07 31.0 5.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFM12211.1 - 5.8e-08 32.7 8.4 1.4e-07 31.5 5.8 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KFM12211.1 - 3.9e-07 29.6 7.5 8.4e-07 28.5 5.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM12211.1 - 7e-07 29.1 9.2 1.6e-06 28.0 6.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM12211.1 - 4.8e-06 26.2 7.6 8.7e-06 25.3 5.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KFM12211.1 - 0.00026 20.6 1.9 0.00026 20.6 1.3 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 KFM12211.1 - 0.00036 20.3 6.3 0.0009 19.0 4.4 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Endonuclease_7 PF02945.10 KFM12211.1 - 0.095 12.4 1.3 0.13 11.9 0.9 1.2 1 0 0 1 1 1 0 Recombination endonuclease VII Prok-RING_1 PF14446.1 KFM12211.1 - 0.16 11.6 8.9 1.2 8.8 6.2 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 FANCL_C PF11793.3 KFM12211.1 - 0.32 10.9 9.5 13 5.8 6.6 2.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.3 KFM12211.1 - 0.52 9.8 4.7 1.1 8.8 3.2 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Vps39_2 PF10367.4 KFM12211.1 - 1.5 9.0 4.4 1.3 9.1 0.5 2.1 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 DSPc PF00782.15 KFM12212.1 - 9.5e-30 102.8 0.0 1.1e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFM12212.1 - 0.00018 20.9 0.0 0.00022 20.6 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Peptidase_M76 PF09768.4 KFM12213.1 - 2.1e-60 203.1 5.9 2.4e-60 202.9 4.1 1.0 1 0 0 1 1 1 1 Peptidase M76 family HypD PF01924.11 KFM12213.1 - 0.024 13.4 0.0 0.033 12.9 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase formation hypA family DUF1045 PF06299.7 KFM12213.1 - 0.1 12.2 0.1 0.24 11.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1045) TPR_11 PF13414.1 KFM12214.1 - 1.5e-45 152.6 24.8 1.3e-17 63.1 0.1 4.5 2 2 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 KFM12214.1 - 2e-34 115.7 26.6 4.4e-06 26.0 0.7 7.2 7 0 0 7 7 6 6 Tetratricopeptide repeat TPR_2 PF07719.12 KFM12214.1 - 6.5e-28 94.3 24.4 7.4e-05 22.3 0.1 6.7 6 0 0 6 6 6 6 Tetratricopeptide repeat RPAP3_C PF13877.1 KFM12214.1 - 1e-27 95.9 1.0 3.4e-27 94.2 0.7 1.9 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_16 PF13432.1 KFM12214.1 - 2.1e-15 56.9 10.9 0.00034 21.1 1.4 5.2 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.1 KFM12214.1 - 4.7e-14 50.9 8.1 6.2e-05 22.5 0.0 5.7 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFM12214.1 - 7.5e-14 50.9 1.9 0.097 13.3 0.0 5.1 4 2 0 4 4 4 4 Tetratricopeptide repeat TPR_9 PF13371.1 KFM12214.1 - 5.4e-12 45.3 4.7 0.0023 17.7 0.3 4.8 3 2 2 5 5 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 KFM12214.1 - 2.4e-11 42.5 17.7 0.029 14.1 0.3 7.2 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 KFM12214.1 - 1e-09 38.1 15.5 0.17 11.8 0.5 4.8 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.1 KFM12214.1 - 1.1e-07 32.0 9.4 0.015 15.5 0.9 4.6 2 2 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFM12214.1 - 1.8e-05 24.5 20.5 0.15 12.3 0.3 7.6 8 0 0 8 8 8 2 Tetratricopeptide repeat MIT PF04212.13 KFM12214.1 - 0.0034 17.2 5.8 0.36 10.7 0.2 4.0 3 1 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 KFM12214.1 - 0.0057 17.0 12.4 9.8 6.8 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 KFM12214.1 - 0.0062 16.6 7.2 0.077 13.1 0.3 3.5 2 2 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 KFM12214.1 - 0.018 14.9 1.4 12 6.1 0.0 4.2 4 0 0 4 4 3 0 PPR repeat Fis1_TPR_C PF14853.1 KFM12214.1 - 0.042 13.7 18.5 0.048 13.5 0.1 5.7 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat Reprolysin_5 PF13688.1 KFM12214.1 - 0.065 13.1 0.1 0.7 9.7 0.0 2.2 2 0 0 2 2 2 0 Metallo-peptidase family M12 RPN7 PF10602.4 KFM12214.1 - 0.13 11.6 0.0 0.13 11.6 0.0 4.0 3 1 2 5 5 5 0 26S proteasome subunit RPN7 TPR_10 PF13374.1 KFM12214.1 - 0.16 11.9 6.0 30 4.7 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat MutS_IV PF05190.13 KFM12214.1 - 0.2 11.8 8.1 0.61 10.2 1.9 3.5 3 0 0 3 3 3 0 MutS family domain IV Yae1_N PF09811.4 KFM12215.1 - 4.6e-10 38.8 31.8 3.3 7.3 22.0 3.2 1 1 0 1 1 1 1 Essential protein Yae1, N terminal LRR_8 PF13855.1 KFM12216.1 - 6.8e-28 96.2 25.8 2.1e-13 49.8 3.5 4.1 1 1 4 5 5 5 4 Leucine rich repeat LRR_4 PF12799.2 KFM12216.1 - 5.6e-17 60.9 15.4 4.2e-09 35.8 0.6 4.2 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM12216.1 - 1.1e-10 40.0 20.6 0.11 12.6 0.1 7.8 7 1 1 8 8 8 3 Leucine Rich Repeat LRR_6 PF13516.1 KFM12216.1 - 1.7e-08 33.6 10.4 0.36 11.0 0.0 6.8 6 0 0 6 6 6 2 Leucine Rich repeat LRR_7 PF13504.1 KFM12216.1 - 2.9e-08 32.6 11.1 0.059 13.5 0.2 6.9 6 0 0 6 6 6 1 Leucine rich repeat LRR_5 PF13306.1 KFM12216.1 - 1.6e-07 31.0 1.0 3.9e-07 29.8 0.7 1.6 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) V-set PF07686.12 KFM12216.1 - 1.7e-06 27.8 0.0 4.4e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin V-set domain LRR_9 PF14580.1 KFM12216.1 - 7.3e-06 25.6 0.3 0.0074 15.8 0.0 2.2 1 1 1 2 2 2 2 Leucine-rich repeat I-set PF07679.11 KFM12216.1 - 0.00016 21.4 0.0 0.00033 20.4 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM12216.1 - 0.001 19.1 0.0 0.0031 17.5 0.0 1.8 2 0 0 2 2 1 1 Immunoglobulin domain ig PF00047.20 KFM12216.1 - 0.0016 18.5 0.0 0.004 17.2 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain LRRNT PF01462.13 KFM12216.1 - 0.003 16.9 2.3 0.003 16.9 1.6 3.3 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain Ig_3 PF13927.1 KFM12216.1 - 0.015 15.7 0.4 0.095 13.2 0.0 2.6 2 0 0 2 2 2 0 Immunoglobulin domain DUF261 PF03196.8 KFM12216.1 - 0.059 13.3 0.1 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF261 Aa_trans PF01490.13 KFM12217.1 - 6.1e-82 275.2 32.5 4.1e-46 157.2 9.0 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein DUF4234 PF14018.1 KFM12217.1 - 0.84 9.4 7.9 0.14 11.8 1.0 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4234) Aa_trans PF01490.13 KFM12218.1 - 6.6e-79 265.2 41.4 7.8e-79 265.0 28.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4234 PF14018.1 KFM12218.1 - 0.025 14.3 2.5 0.16 11.7 1.7 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) Herpes_US9 PF06072.6 KFM12218.1 - 0.66 9.8 0.0 0.66 9.8 0.0 3.0 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 Aa_trans PF01490.13 KFM12219.1 - 2.3e-76 256.8 38.5 2.9e-76 256.5 26.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Cation_ATPase_C PF00689.16 KFM12219.1 - 1.7e-05 24.3 10.7 1.7e-05 24.3 7.4 3.0 1 1 1 3 3 3 1 Cation transporting ATPase, C-terminus ARID PF01388.16 KFM12221.1 - 3.6e-25 87.6 0.1 3.4e-23 81.3 0.0 2.7 2 0 0 2 2 2 2 ARID/BRIGHT DNA binding domain RFX_DNA_binding PF02257.10 KFM12221.1 - 1e-08 35.1 0.0 2.3e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain RRM_5 PF13893.1 KFM12222.1 - 1.6e-40 136.7 1.0 1e-12 47.7 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM12222.1 - 1.9e-35 120.6 0.1 2.9e-09 36.7 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFM12222.1 - 4.1e-31 106.4 0.2 2e-09 36.9 0.0 5.1 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_transf_21 PF13506.1 KFM12223.1 - 4.4e-55 185.6 0.0 6.7e-55 185.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 KFM12223.1 - 1.5e-28 100.1 0.0 1.9e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KFM12223.1 - 4.6e-14 52.5 6.0 5.7e-14 52.2 4.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 KFM12223.1 - 3.2e-05 23.6 0.0 6.8e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 2 Chitin_synth_2 PF03142.10 KFM12223.1 - 0.024 13.0 0.0 0.042 12.2 0.0 1.3 1 0 0 1 1 1 0 Chitin synthase G-gamma PF00631.17 KFM12224.1 - 2.1e-09 36.9 0.0 2.2e-09 36.9 0.0 1.0 1 0 0 1 1 1 1 GGL domain SurA_N_3 PF13624.1 KFM12225.1 - 0.0027 17.6 1.6 0.031 14.2 0.1 2.1 2 0 0 2 2 2 1 SurA N-terminal domain AsmA_1 PF13109.1 KFM12225.1 - 0.034 13.4 0.9 0.058 12.6 0.1 1.7 2 0 0 2 2 2 0 AsmA-like C-terminal region Tmemb_161AB PF10268.4 KFM12225.1 - 0.039 12.4 0.2 0.066 11.7 0.2 1.3 1 0 0 1 1 1 0 Predicted transmembrane protein 161AB Ecm29 PF13001.2 KFM12226.1 - 1.1e-155 518.9 0.2 1.1e-154 515.7 0.1 2.6 3 0 0 3 3 3 1 Proteasome stabiliser HEAT_2 PF13646.1 KFM12226.1 - 1e-16 60.9 10.2 0.013 15.7 0.1 9.1 9 1 0 9 9 9 4 HEAT repeats HEAT PF02985.17 KFM12226.1 - 5e-15 54.1 9.9 0.044 13.8 0.0 11.3 13 0 0 13 13 13 4 HEAT repeat Vac14_Fab1_bd PF12755.2 KFM12226.1 - 1.9e-12 47.3 0.1 0.00076 19.8 0.0 8.2 7 1 2 9 9 9 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KFM12226.1 - 4.1e-12 46.1 17.5 0.69 10.4 0.2 11.3 11 3 3 14 14 14 5 HEAT-like repeat CLASP_N PF12348.3 KFM12226.1 - 0.00023 20.6 3.0 0.084 12.2 0.1 4.7 4 1 0 4 4 4 1 CLASP N terminal Cnd1 PF12717.2 KFM12226.1 - 0.0027 17.5 7.8 23 4.7 0.0 6.9 8 0 0 8 8 8 0 non-SMC mitotic condensation complex subunit 1 Catalase-rel PF06628.7 KFM12226.1 - 0.2 11.5 0.0 15 5.5 0.0 3.2 2 0 0 2 2 2 0 Catalase-related immune-responsive ADH_zinc_N PF00107.21 KFM12227.1 - 1.8e-23 82.5 0.0 2.7e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFM12227.1 - 7.7e-09 36.5 0.0 2.3e-08 34.9 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Thioredoxin PF00085.15 KFM12228.1 - 4.5e-31 106.6 1.0 4.9e-31 106.4 0.7 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KFM12228.1 - 2.1e-07 30.9 0.2 3.4e-07 30.3 0.2 1.4 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KFM12228.1 - 6.1e-07 29.6 0.2 6.1e-06 26.4 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KFM12228.1 - 0.00074 19.4 0.3 0.0012 18.7 0.2 1.4 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 KFM12228.1 - 0.0017 18.0 0.2 0.0023 17.6 0.2 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.1 KFM12228.1 - 0.0022 17.5 0.3 0.0038 16.7 0.1 1.6 1 1 1 2 2 2 1 Thioredoxin DIM1 PF02966.11 KFM12228.1 - 0.0051 16.3 0.1 0.0056 16.1 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Glutaredoxin PF00462.19 KFM12228.1 - 0.0056 16.6 0.6 0.01 15.8 0.4 1.5 1 0 0 1 1 1 1 Glutaredoxin Redoxin PF08534.5 KFM12228.1 - 0.066 12.7 0.4 0.097 12.2 0.2 1.4 1 1 0 1 1 1 0 Redoxin Pkinase_Tyr PF07714.12 KFM12229.1 - 2e-94 315.4 0.0 2.8e-94 315.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase I-set PF07679.11 KFM12229.1 - 2.7e-45 152.1 0.0 2.5e-20 72.0 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Pkinase PF00069.20 KFM12229.1 - 1.9e-42 145.1 0.0 4.5e-42 144.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Ig_2 PF13895.1 KFM12229.1 - 6.9e-29 99.8 0.0 7.3e-13 48.4 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Kringle PF00051.13 KFM12229.1 - 1.2e-24 86.1 6.4 3.1e-24 84.8 4.5 1.7 1 0 0 1 1 1 1 Kringle domain Ig_3 PF13927.1 KFM12229.1 - 6.7e-21 74.5 6.1 4.7e-09 36.6 0.0 4.6 4 1 0 4 4 4 3 Immunoglobulin domain Fz PF01392.17 KFM12229.1 - 1.9e-20 73.3 4.9 4.1e-20 72.2 3.4 1.6 1 0 0 1 1 1 1 Fz domain ig PF00047.20 KFM12229.1 - 3.9e-18 65.3 0.1 7.4e-07 29.2 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 KFM12229.1 - 8.3e-14 51.4 0.0 7.5e-07 29.0 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM12229.1 - 4.3e-10 39.3 0.1 0.012 15.5 0.0 3.7 3 0 0 3 3 3 3 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.11 KFM12229.1 - 8.8e-07 27.5 0.0 0.015 13.6 0.0 3.1 2 1 0 3 3 3 2 Alphaherpesvirus glycoprotein E Kinase-like PF14531.1 KFM12229.1 - 0.024 13.6 0.0 0.041 12.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like EphA2_TM PF14575.1 KFM12229.1 - 0.033 14.5 0.1 0.067 13.5 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 KFM12229.1 - 0.089 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family IncA PF04156.9 KFM12229.1 - 0.21 11.1 0.0 0.33 10.5 0.0 1.2 1 0 0 1 1 1 0 IncA protein 7tm_1 PF00001.16 KFM12231.1 - 2.4e-40 138.2 24.4 3.2e-40 137.9 16.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Abhydrolase_9_N PF15420.1 KFM12231.1 - 0.15 11.8 13.6 0.057 13.1 6.3 2.1 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Guanylate_cyc PF00211.15 KFM12232.1 - 2.5e-65 219.2 0.2 2.3e-64 216.1 0.0 2.1 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.12 KFM12232.1 - 4.2e-42 144.0 0.0 6.6e-42 143.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM12232.1 - 3.1e-36 124.8 0.0 6.2e-36 123.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.9 KFM12232.1 - 2.6e-06 26.8 0.5 4.2e-06 26.1 0.4 1.3 1 0 0 1 1 1 1 Heme NO binding associated zf-RING_2 PF13639.1 KFM12234.1 - 1.8e-09 37.3 8.1 1.8e-09 37.3 5.6 2.6 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFM12234.1 - 4.4e-09 36.2 8.5 4.4e-09 36.2 5.9 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM12234.1 - 5.2e-09 35.6 7.3 5.2e-09 35.6 5.1 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM12234.1 - 1.1e-08 34.6 5.2 1.1e-08 34.6 3.6 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM12234.1 - 2.2e-06 27.2 8.1 2.2e-06 27.2 5.6 2.7 3 0 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFM12234.1 - 1.7e-05 24.5 8.1 1.7e-05 24.5 5.6 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KFM12234.1 - 9.3e-05 22.4 3.7 9.3e-05 22.4 2.6 2.8 3 0 0 3 3 3 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KFM12234.1 - 0.0027 17.4 3.2 0.0078 16.0 2.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KFM12234.1 - 0.0031 17.1 5.8 0.011 15.4 4.0 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 KFM12234.1 - 0.14 11.9 2.2 0.36 10.6 1.6 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 KFM12234.1 - 2 8.0 14.7 0.25 10.9 6.2 2.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 KFM12235.1 - 9.9e-68 223.7 0.1 1.7e-21 75.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM12235.1 - 3e-39 132.8 0.0 2.2e-13 49.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM12235.1 - 5.8e-30 102.9 0.1 8.1e-12 44.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFM12235.1 - 0.00021 21.0 0.0 0.12 12.2 0.0 2.5 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 KFM12235.1 - 0.017 14.8 0.0 9.6 6.0 0.0 2.8 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_2 PF04059.7 KFM12235.1 - 0.059 13.3 0.1 0.42 10.6 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif 2 RNA_bind PF08675.6 KFM12235.1 - 0.11 12.4 0.0 4.3 7.3 0.0 2.9 3 2 0 3 3 3 0 RNA binding domain CAAP1 PF15335.1 KFM12237.1 - 1.6e-33 114.6 9.8 2.6e-33 113.9 6.8 1.4 1 0 0 1 1 1 1 Caspase activity and apoptosis inhibitor 1 PUL PF08324.6 KFM12238.1 - 6.5e-69 231.6 5.3 8.8e-69 231.2 3.7 1.2 1 0 0 1 1 1 1 PUL domain WD40 PF00400.27 KFM12238.1 - 2.8e-44 147.4 12.4 4e-10 39.1 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat PFU PF09070.6 KFM12238.1 - 3.6e-43 146.2 0.1 7e-43 145.3 0.1 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) GAGE PF05831.6 KFM12238.1 - 0.086 12.9 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 GAGE protein Pkinase_Tyr PF07714.12 KFM12239.1 - 2.6e-91 305.2 0.0 3.8e-91 304.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM12239.1 - 2.1e-47 161.5 0.0 3.6e-47 160.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ig_Tie2_1 PF10430.4 KFM12239.1 - 6.5e-33 112.9 0.1 1.6e-32 111.6 0.0 1.7 1 0 0 1 1 1 1 Tie-2 Ig-like domain 1 fn3 PF00041.16 KFM12239.1 - 1.1e-29 102.3 4.3 7.8e-12 45.1 0.5 3.5 3 0 0 3 3 3 3 Fibronectin type III domain I-set PF07679.11 KFM12239.1 - 3.7e-06 26.7 0.0 0.00024 20.8 0.0 3.4 3 0 0 3 3 3 1 Immunoglobulin I-set domain APH PF01636.18 KFM12239.1 - 0.0011 18.7 0.0 0.12 12.1 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family hEGF PF12661.2 KFM12239.1 - 0.0015 18.4 31.1 0.0038 17.2 1.9 5.0 4 0 0 4 4 4 2 Human growth factor-like EGF EGF_2 PF07974.8 KFM12239.1 - 0.0024 17.9 13.6 0.0024 17.9 9.5 5.0 5 0 0 5 5 5 2 EGF-like domain Laminin_EGF PF00053.19 KFM12239.1 - 0.02 14.8 50.1 1.5 8.7 12.2 4.3 2 1 2 4 4 4 0 Laminin EGF-like (Domains III and V) V-set PF07686.12 KFM12239.1 - 0.03 14.1 0.0 0.63 9.9 0.0 3.0 3 0 0 3 3 3 0 Immunoglobulin V-set domain Mob1_phocein PF03637.12 KFM12240.1 - 2.3e-81 271.6 0.3 2.6e-81 271.4 0.2 1.0 1 0 0 1 1 1 1 Mob1/phocein family C9orf72-like PF15019.1 KFM12241.1 - 8.3e-85 283.7 0.0 1.3e-84 283.0 0.0 1.3 1 0 0 1 1 1 1 C9orf72-like protein family LRR_8 PF13855.1 KFM12242.1 - 1.1e-68 226.8 72.7 1.3e-12 47.2 1.4 6.4 1 1 6 8 8 8 8 Leucine rich repeat LRR_5 PF13306.1 KFM12242.1 - 6.1e-26 90.6 0.0 1.1e-10 41.2 0.0 3.2 2 1 1 3 3 3 3 Leucine rich repeats (6 copies) LRR_4 PF12799.2 KFM12242.1 - 2.8e-23 81.0 32.9 1.8e-06 27.4 0.3 7.0 4 2 1 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM12242.1 - 2.4e-17 60.3 32.8 0.12 12.4 0.0 12.2 12 0 0 12 12 12 5 Leucine Rich Repeat I-set PF07679.11 KFM12242.1 - 4.5e-17 61.6 0.0 7.3e-17 61.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.1 KFM12242.1 - 4.2e-07 30.3 0.0 3.1e-06 27.5 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.1 KFM12242.1 - 6.4e-07 29.3 0.9 9.1e-07 28.9 0.0 1.7 2 0 0 2 2 1 1 Immunoglobulin domain V-set PF07686.12 KFM12242.1 - 2.7e-05 24.0 0.0 0.0001 22.2 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin V-set domain LRR_6 PF13516.1 KFM12242.1 - 3.4e-05 23.4 33.3 0.052 13.6 0.0 10.2 10 1 1 11 11 11 2 Leucine Rich repeat LRRNT PF01462.13 KFM12242.1 - 6.7e-05 22.2 2.6 6.7e-05 22.2 1.8 3.0 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_7 PF13504.1 KFM12242.1 - 0.001 18.9 38.0 9.4 6.9 0.1 11.3 12 0 0 12 12 11 1 Leucine rich repeat ig PF00047.20 KFM12242.1 - 0.027 14.5 0.3 0.12 12.5 0.0 2.4 2 1 0 2 2 1 0 Immunoglobulin domain LRR_9 PF14580.1 KFM12242.1 - 0.18 11.3 7.4 0.18 11.3 0.8 3.1 2 2 2 4 4 4 0 Leucine-rich repeat FixQ PF05545.6 KFM12242.1 - 4.2 7.1 5.1 0.52 10.0 0.5 1.7 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ PDZ PF00595.19 KFM12244.1 - 2.5e-20 72.4 0.2 1.7e-15 56.9 0.0 2.6 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM12244.1 - 7e-08 32.2 0.0 2.1e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.1 KFM12244.1 - 0.0038 16.9 0.0 0.0096 15.6 0.0 1.6 1 0 0 1 1 1 1 Tricorn protease PDZ domain Glyco_transf_8 PF01501.15 KFM12245.1 - 2.8e-11 43.2 0.1 4.5e-11 42.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 LMBR1 PF04791.11 KFM12246.1 - 0.19 10.2 4.7 0.22 10.0 3.2 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein MOR2-PAG1_N PF14222.1 KFM12246.1 - 0.4 9.3 4.5 0.45 9.1 3.1 1.0 1 0 0 1 1 1 0 Cell morphogenesis N-terminal RAP1 PF07218.6 KFM12246.1 - 4.8 5.1 11.6 5.4 4.9 8.0 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CPSF100_C PF13299.1 KFM12246.1 - 6 7.0 9.1 2.2 8.4 4.4 1.6 1 1 1 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Macoilin PF09726.4 KFM12246.1 - 7.7 4.6 12.7 8.2 4.5 8.8 1.0 1 0 0 1 1 1 0 Transmembrane protein RRM_1 PF00076.17 KFM12247.1 - 2.3e-22 78.4 0.2 3.8e-22 77.7 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM12247.1 - 5.1e-19 68.0 0.1 8.3e-19 67.3 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM12247.1 - 4.4e-14 52.0 0.2 7.3e-14 51.3 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 KFM12247.1 - 0.0001 22.0 1.6 0.00018 21.2 1.1 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 KFM12247.1 - 0.018 14.7 0.8 0.035 13.8 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle Limkain-b1 PF11608.3 KFM12247.1 - 0.019 14.7 0.3 0.084 12.6 0.2 2.1 1 1 0 1 1 1 0 Limkain b1 SET_assoc PF11767.3 KFM12247.1 - 0.071 12.4 0.0 0.16 11.2 0.0 1.6 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated CDC27 PF09507.5 KFM12247.1 - 0.38 9.9 12.9 0.57 9.3 8.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PET PF06297.9 KFM12248.1 - 3.2e-44 148.9 0.1 7.2e-44 147.7 0.1 1.6 1 0 0 1 1 1 1 PET Domain LIM PF00412.17 KFM12248.1 - 2.8e-25 88.1 40.0 9.9e-10 38.3 2.1 3.6 3 0 0 3 3 3 3 LIM domain Vasculin PF15337.1 KFM12248.1 - 0.0069 16.8 0.1 0.0069 16.8 0.0 2.5 2 0 0 2 2 2 1 Vascular protein family Vasculin-like 1 GON PF08685.6 KFM12249.1 - 1.2e-85 286.4 0.9 1.2e-85 286.4 0.6 2.6 2 0 0 2 2 2 1 GON domain TSP_1 PF00090.14 KFM12249.1 - 3e-47 158.4 202.6 1.9e-07 31.0 5.1 17.8 19 0 0 19 19 17 12 Thrombospondin type 1 domain ADAM_spacer1 PF05986.9 KFM12249.1 - 2.9e-33 114.1 0.1 5e-33 113.3 0.1 1.4 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Pep_M12B_propep PF01562.14 KFM12249.1 - 4.4e-31 107.3 0.2 8.3e-31 106.5 0.2 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.14 KFM12249.1 - 1.4e-26 93.3 0.8 3e-26 92.2 0.5 1.6 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.1 KFM12249.1 - 5.4e-12 46.0 1.5 1.1e-11 45.0 1.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KFM12249.1 - 1.8e-09 38.1 0.0 4.3e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFM12249.1 - 1.9e-08 34.1 0.4 3.6e-08 33.1 0.3 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFM12249.1 - 2.3e-08 34.3 0.5 4.3e-08 33.4 0.3 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like DUF955 PF06114.8 KFM12249.1 - 0.092 12.4 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF955) DUF3285 PF11688.3 KFM12249.1 - 0.16 11.6 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3285) TruD PF01142.13 KFM12250.1 - 1.4e-59 201.6 0.0 1.9e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) R3H PF01424.17 KFM12250.1 - 0.00064 19.3 0.2 0.03 13.9 0.0 3.2 3 1 0 3 3 3 1 R3H domain Pkinase PF00069.20 KFM12251.1 - 5.9e-54 182.9 0.0 8.1e-54 182.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM12251.1 - 5.7e-50 169.7 0.0 9.9e-50 169.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Death PF00531.17 KFM12251.1 - 0.00099 18.8 0.0 0.0029 17.3 0.0 1.8 2 0 0 2 2 2 1 Death domain Focal_AT PF03623.8 KFM12251.1 - 0.043 13.3 0.1 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 Focal adhesion targeting region Cofilin_ADF PF00241.15 KFM12252.1 - 2e-26 92.3 0.1 2.9e-15 56.2 0.0 2.3 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein TMEM117 PF15113.1 KFM12253.1 - 3.8e-245 813.0 26.8 4.4e-245 812.8 18.5 1.0 1 0 0 1 1 1 1 TMEM117 protein family DUF202 PF02656.10 KFM12253.1 - 1.8 8.8 5.6 4 7.7 0.0 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF202) 7tm_1 PF00001.16 KFM12254.1 - 1e-34 119.8 22.7 1e-34 119.8 15.7 1.3 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Gemini_mov PF01708.11 KFM12254.1 - 0.64 9.5 2.8 0.81 9.2 0.1 2.3 2 0 0 2 2 2 0 Geminivirus putative movement protein DUF1129 PF06570.6 KFM12254.1 - 6.6 5.9 14.6 13 5.0 3.5 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) Hormone_1 PF00103.15 KFM12255.1 - 1.3e-26 93.2 1.0 1.5e-26 93.1 0.7 1.0 1 0 0 1 1 1 1 Somatotropin hormone family Mating_N PF12731.2 KFM12255.1 - 0.037 13.8 0.2 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 Mating-type protein beta 1 Homeobox PF00046.24 KFM12256.1 - 1.4e-21 75.8 5.3 2.8e-21 74.8 3.7 1.5 1 0 0 1 1 1 1 Homeobox domain DUF2986 PF11661.3 KFM12256.1 - 0.0016 18.7 0.5 0.0016 18.7 0.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2986) Homez PF11569.3 KFM12256.1 - 0.075 12.1 0.8 0.15 11.1 0.2 1.8 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.6 KFM12256.1 - 0.12 12.1 0.4 0.34 10.6 0.1 1.9 2 0 0 2 2 2 0 Homeobox KN domain Anoctamin PF04547.7 KFM12257.1 - 6.5e-148 493.1 20.0 8.9e-148 492.6 13.9 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel Ctr PF04145.10 KFM12257.1 - 0.19 11.8 4.2 11 6.0 0.1 3.4 4 0 0 4 4 4 0 Ctr copper transporter family SPT6_acidic PF14632.1 KFM12257.1 - 0.83 9.8 6.0 1.6 8.9 1.2 2.2 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Halogen_Hydrol PF10112.4 KFM12257.1 - 5.6 6.3 11.0 0.11 11.8 0.4 3.0 3 0 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein 7tm_1 PF00001.16 KFM12258.1 - 6.5e-44 149.9 25.4 7.8e-44 149.7 17.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 KFM12258.1 - 3.3e-06 26.4 21.5 4.9e-06 25.8 14.9 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Git3 PF11710.3 KFM12258.1 - 0.97 8.9 23.4 0.42 10.1 10.2 2.2 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 DUF4233 PF14017.1 KFM12258.1 - 5.9 6.8 18.6 4.9 7.1 1.2 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4233) Cadherin PF00028.12 KFM12259.1 - 0 1014.4 54.2 6.8e-23 80.7 0.0 21.7 22 0 0 22 22 22 21 Cadherin domain Laminin_G_2 PF02210.19 KFM12259.1 - 1.5e-23 83.2 0.7 3e-22 79.0 0.1 3.0 3 0 0 3 3 3 1 Laminin G domain Laminin_G_1 PF00054.18 KFM12259.1 - 5.7e-18 65.1 0.0 4.5e-17 62.2 0.0 2.6 2 0 0 2 2 2 1 Laminin G domain EGF PF00008.22 KFM12259.1 - 7e-14 51.4 57.9 6e-05 22.9 7.3 4.6 4 0 0 4 4 4 4 EGF-like domain Cadherin_2 PF08266.7 KFM12259.1 - 2.8e-13 49.2 0.0 0.66 9.5 0.0 10.7 12 0 0 12 12 12 2 Cadherin-like EGF_CA PF07645.10 KFM12259.1 - 4.5e-05 23.3 11.0 4.5e-05 23.3 7.6 4.4 3 1 1 4 4 4 1 Calcium-binding EGF domain MLANA PF14991.1 KFM12259.1 - 0.0011 18.9 0.0 0.0032 17.4 0.0 1.8 1 0 0 1 1 1 1 Protein melan-A CHORD PF04968.7 KFM12261.1 - 1.3e-48 163.1 16.1 2.5e-28 98.1 4.2 2.7 3 0 0 3 3 3 2 CHORD CS PF04969.11 KFM12261.1 - 1.3e-17 64.0 0.1 3.2e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 CS domain Cupin_8 PF13621.1 KFM12261.1 - 0.03 13.8 0.0 0.069 12.6 0.0 1.6 1 1 0 1 1 1 0 Cupin-like domain DUF2733 PF10813.3 KFM12261.1 - 0.041 13.4 5.9 1.8 8.1 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2733) TFR_dimer PF04253.10 KFM12262.1 - 2e-39 133.9 0.0 6.7e-39 132.3 0.0 1.9 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 KFM12262.1 - 6.8e-16 58.5 0.0 1.8e-15 57.1 0.0 1.8 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KFM12262.1 - 2.7e-12 46.2 0.1 6.7e-12 44.9 0.0 1.7 1 0 0 1 1 1 1 PA domain IQ-like PF15157.1 KFM12262.1 - 0.015 15.4 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 IQ-like TFR_dimer PF04253.10 KFM12263.1 - 4.8e-40 135.9 0.0 1e-39 134.9 0.0 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 KFM12263.1 - 4.2e-15 55.9 0.0 9.2e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KFM12263.1 - 2.9e-13 49.3 0.0 7.6e-13 48.0 0.0 1.7 2 0 0 2 2 2 1 PA domain NAD_binding_6 PF08030.7 KFM12264.1 - 7.8e-22 77.8 0.0 3e-20 72.7 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KFM12264.1 - 4.6e-19 68.7 4.2 8e-19 67.9 2.9 1.4 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KFM12264.1 - 7.7e-16 57.8 0.0 1.6e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 KFM12264.1 - 0.008 16.7 0.0 0.058 13.9 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cytochrom_B_N PF00033.14 KFM12264.1 - 0.031 13.6 1.2 0.53 9.6 0.1 2.3 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB FAD_binding_6 PF00970.19 KFM12264.1 - 0.083 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Ni_hydr_CYTB PF01292.15 KFM12264.1 - 1.7 7.9 8.1 2.9 7.2 0.2 2.2 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 Tyrosinase PF00264.15 KFM12265.1 - 1.3e-44 153.0 0.8 2.1e-44 152.3 0.5 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Laminin_EGF PF00053.19 KFM12265.1 - 0.36 10.8 13.7 0.13 12.2 6.0 2.5 2 1 0 2 2 2 0 Laminin EGF-like (Domains III and V) 7tm_3 PF00003.17 KFM12266.1 - 9.1e-74 247.7 25.0 1.3e-73 247.2 17.3 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.23 KFM12266.1 - 1.3e-46 159.0 0.0 1.8e-46 158.5 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region GluR_Homer-bdg PF10606.4 KFM12266.1 - 5.8e-25 86.9 11.7 2.1e-24 85.1 8.1 2.1 1 0 0 1 1 1 1 Homer-binding domain of metabotropic glutamate receptor NCD3G PF07562.9 KFM12266.1 - 1.6e-18 66.1 12.7 3.1e-18 65.2 8.8 1.5 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.1 KFM12266.1 - 0.0015 17.9 0.0 0.0046 16.3 0.0 1.7 2 0 0 2 2 2 1 Periplasmic binding protein Ras PF00071.17 KFM12267.1 - 3.7e-42 143.4 0.0 4.4e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM12267.1 - 2.3e-18 66.8 0.0 3.3e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM12267.1 - 4.4e-10 39.0 0.1 4.9e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFM12267.1 - 1.8e-07 30.5 0.0 2.1e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFM12267.1 - 0.00088 18.7 0.1 0.023 14.1 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KFM12267.1 - 0.0057 16.8 0.0 0.0082 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 KFM12267.1 - 0.0097 15.8 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 KFM12267.1 - 0.043 13.3 0.0 0.54 9.7 0.0 2.4 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 KFM12267.1 - 0.14 11.8 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Tim17 PF02466.14 KFM12268.1 - 1.6e-07 31.4 0.1 3.5e-07 30.3 0.1 1.6 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF4010 PF13194.1 KFM12268.1 - 0.053 12.8 0.7 0.11 11.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4010) Frizzled PF01534.12 KFM12269.1 - 1.8e-135 450.9 24.2 4.9e-133 442.9 16.7 2.0 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.17 KFM12269.1 - 7.7e-18 64.9 2.7 1.4e-17 64.0 1.9 1.5 1 0 0 1 1 1 1 Fz domain TctB PF07331.6 KFM12269.1 - 0.028 14.0 0.3 0.028 14.0 0.2 3.3 2 2 1 3 3 3 0 Tripartite tricarboxylate transporter TctB family Ndc1_Nup PF09531.5 KFM12269.1 - 2.1 6.6 10.8 0.019 13.4 1.8 1.7 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Trypsin PF00089.21 KFM12270.1 - 3.9e-11 42.9 0.1 3e-10 40.0 0.1 2.3 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 KFM12270.1 - 1.9e-07 31.0 0.0 3.4e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Pribosyl_synth PF14572.1 KFM12271.1 - 1.2e-44 152.2 2.5 8.1e-38 130.0 1.3 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 KFM12271.1 - 3.3e-34 117.1 0.5 2.1e-33 114.4 0.0 2.3 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 KFM12271.1 - 2.4e-10 40.2 1.0 5.8e-10 38.9 0.5 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KFM12271.1 - 0.00011 21.5 0.1 0.00017 20.9 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Ras PF00071.17 KFM12272.1 - 8.2e-57 191.1 0.0 1.1e-56 190.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM12272.1 - 6.5e-19 68.5 0.0 9.7e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM12272.1 - 5.3e-10 38.8 0.0 5.8e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFM12272.1 - 2.4e-06 26.8 0.0 5.6e-06 25.6 0.0 1.6 1 1 1 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFM12272.1 - 2.6e-06 27.3 0.0 4.1e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFM12272.1 - 1.2e-05 24.8 0.0 1.5e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KFM12272.1 - 0.0029 16.8 0.1 0.01 15.0 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KFM12272.1 - 0.012 15.6 0.0 0.07 13.1 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Arch_ATPase PF01637.13 KFM12272.1 - 0.057 13.0 0.1 0.3 10.7 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase FeoB_N PF02421.13 KFM12272.1 - 0.067 12.4 0.0 0.15 11.3 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.1 KFM12272.1 - 0.079 13.1 0.0 0.13 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain Myelin_PLP PF01275.14 KFM12273.1 - 5.2e-93 310.8 10.9 9.6e-63 211.7 1.6 2.0 2 0 0 2 2 2 2 Myelin proteolipid protein (PLP or lipophilin) Neur_chan_LBD PF02931.18 KFM12274.1 - 1.8e-55 187.4 0.1 2.5e-55 186.9 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFM12274.1 - 2.5e-44 151.9 1.2 4.1e-38 131.6 0.1 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Melibiase PF02065.13 KFM12275.1 - 1.1e-12 47.3 0.0 3.3e-12 45.7 0.0 1.7 1 1 1 2 2 2 1 Melibiase Ribosomal_L44 PF00935.14 KFM12276.1 - 1.8e-32 111.1 9.5 1.8e-32 111.1 6.6 1.7 1 1 1 2 2 2 1 Ribosomal protein L44 Pkinase_Tyr PF07714.12 KFM12277.1 - 5.7e-93 310.7 0.0 7.8e-93 310.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM12277.1 - 8.3e-48 162.7 0.0 1.2e-47 162.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 KFM12277.1 - 6.7e-23 80.2 0.1 1.5e-22 79.2 0.1 1.6 1 0 0 1 1 1 1 SH2 domain BTK PF00779.14 KFM12277.1 - 1e-15 56.9 2.3 2.5e-15 55.7 1.6 1.7 1 0 0 1 1 1 1 BTK motif SH3_1 PF00018.23 KFM12277.1 - 4.1e-14 51.6 0.1 9.4e-14 50.5 0.0 1.7 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 KFM12277.1 - 4e-12 46.2 0.8 2.3e-09 37.3 0.1 2.5 2 0 0 2 2 2 2 PH domain SH3_9 PF14604.1 KFM12277.1 - 4.5e-09 35.7 0.1 1e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFM12277.1 - 4.3e-07 29.3 0.0 1.1e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain Kinase-like PF14531.1 KFM12277.1 - 0.00014 20.9 0.0 0.0002 20.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like SH3_3 PF08239.6 KFM12277.1 - 0.00021 21.4 0.0 0.00049 20.2 0.0 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain APH PF01636.18 KFM12277.1 - 0.05 13.3 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-Tim10_DDP PF02953.10 KFM12278.1 - 2.7e-12 45.7 0.1 3.4e-12 45.4 0.1 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Mg_trans_NIPA PF05653.9 KFM12279.1 - 1.7e-123 411.4 12.6 1.9e-123 411.2 8.7 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 KFM12279.1 - 3.5e-10 40.0 2.0 3.5e-10 40.0 1.4 2.9 2 1 1 3 3 3 2 Multidrug resistance efflux transporter EamA PF00892.15 KFM12279.1 - 2.3e-07 30.8 4.3 2.3e-07 30.8 3.0 3.3 2 1 1 3 3 3 1 EamA-like transporter family DUF4064 PF13273.1 KFM12279.1 - 1.9 8.6 15.2 0.4 10.8 0.6 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Multi_Drug_Res PF00893.14 KFM12279.1 - 4.2 7.8 11.3 1 9.8 2.1 3.3 2 2 1 3 3 3 0 Small Multidrug Resistance protein DUF1282 PF06930.7 KFM12279.1 - 6.1 6.4 13.2 2.5 7.7 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1282) TAFII55_N PF04658.8 KFM12280.1 - 8.2e-57 191.2 0.3 8.2e-57 191.2 0.2 2.0 2 1 0 2 2 2 1 TAFII55 protein conserved region Mo25 PF08569.6 KFM12280.1 - 0.1 11.6 8.7 0.2 10.6 6.1 1.4 1 0 0 1 1 1 0 Mo25-like Atg14 PF10186.4 KFM12280.1 - 6.3 5.6 17.2 9.7 5.0 11.9 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TPR_11 PF13414.1 KFM12281.1 - 9.9e-09 34.7 4.6 1.4e-05 24.6 1.3 2.5 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 KFM12281.1 - 5.5e-06 25.8 4.3 0.0038 17.0 0.2 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 KFM12281.1 - 0.052 13.6 2.1 0.15 12.1 0.9 2.3 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.12 KFM12281.1 - 0.061 13.6 3.7 0.1 12.8 2.5 1.5 1 0 0 1 1 1 0 Bacterial transcriptional activator domain DUF1932 PF09130.6 KFM12281.1 - 0.32 10.7 2.8 4.7 7.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1932) TPR_1 PF00515.23 KFM12281.1 - 1.5 8.5 7.1 2.8 7.6 0.3 3.6 2 1 2 4 4 4 0 Tetratricopeptide repeat CENP-I PF07778.6 KFM12282.1 - 1.9e-233 775.3 15.6 2.5e-233 774.9 10.8 1.1 1 0 0 1 1 1 1 Mis6 DoxX_2 PF13564.1 KFM12283.1 - 2.7e-08 33.6 2.0 4.6e-08 32.9 1.4 1.3 1 1 0 1 1 1 1 DoxX-like family DUF4131 PF13567.1 KFM12283.1 - 0.012 15.0 0.1 0.13 11.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF843 PF05814.6 KFM12283.1 - 0.15 11.8 0.2 0.15 11.8 0.2 1.7 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) HCV_NS2 PF01538.13 KFM12283.1 - 0.15 11.4 1.6 0.2 11.0 1.1 1.2 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS2 DUF308 PF03729.8 KFM12283.1 - 1.2 9.1 0.0 1.2 9.1 0.0 3.1 2 1 0 2 2 2 0 Short repeat of unknown function (DUF308) NS3_envE PF02723.9 KFM12283.1 - 7.8 6.5 6.3 6 6.8 0.5 2.6 2 1 0 2 2 2 0 Non-structural protein NS3/Small envelope protein E Methyltransf_31 PF13847.1 KFM12284.1 - 6.9e-15 54.9 0.0 1.2e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 KFM12284.1 - 9.7e-14 50.8 0.0 2.3e-12 46.2 0.0 2.4 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_18 PF12847.2 KFM12284.1 - 1.4e-08 35.3 0.0 2.9e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFM12284.1 - 1.5e-08 34.6 0.0 3.5e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFM12284.1 - 1.7e-07 30.7 0.0 3.7e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KFM12284.1 - 5e-06 26.7 0.0 1.5e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KFM12284.1 - 9.2e-05 21.5 0.0 0.00018 20.6 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase UPF0020 PF01170.13 KFM12284.1 - 0.0016 18.0 0.1 0.003 17.1 0.1 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_15 PF09445.5 KFM12284.1 - 0.0023 17.5 0.0 0.0038 16.8 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.1 KFM12284.1 - 0.0048 16.5 0.0 0.0087 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFM12284.1 - 0.0057 15.7 0.0 0.0094 15.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 KFM12284.1 - 0.013 14.6 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 KFM12284.1 - 0.018 15.5 0.0 0.048 14.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KFM12284.1 - 0.032 14.7 0.0 0.06 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.6 KFM12284.1 - 0.095 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) DKCLD PF08068.7 KFM12285.1 - 7.8e-23 80.1 0.5 5.8e-22 77.3 0.0 2.5 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 KFM12285.1 - 2.5e-21 76.4 6.6 4.3e-20 72.3 0.1 3.7 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 KFM12285.1 - 7.1e-18 64.1 1.0 1.7e-17 62.8 0.7 1.7 1 0 0 1 1 1 1 PUA domain Guanylate_kin PF00625.16 KFM12286.1 - 3.5e-59 199.3 0.3 6.3e-59 198.4 0.2 1.4 1 0 0 1 1 1 1 Guanylate kinase PDZ PF00595.19 KFM12286.1 - 1.9e-18 66.3 2.1 3.3e-18 65.6 0.7 1.9 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) SH3_2 PF07653.12 KFM12286.1 - 3.3e-10 39.3 0.0 8.9e-10 37.9 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM12286.1 - 1.1e-08 34.3 0.7 5e-08 32.2 0.5 2.1 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFM12286.1 - 2.7e-07 30.0 0.0 5.7e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PDZ_2 PF13180.1 KFM12286.1 - 3e-05 23.8 0.2 0.0002 21.1 0.1 2.2 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.1 KFM12286.1 - 0.00062 19.5 0.4 0.15 11.8 0.1 3.4 3 1 0 3 3 3 1 Tricorn protease PDZ domain DUF258 PF03193.11 KFM12286.1 - 0.00073 18.7 0.0 0.002 17.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KFM12286.1 - 0.02 14.8 0.0 0.047 13.6 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase RBFA PF02033.13 KFM12286.1 - 0.057 13.4 0.1 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 Ribosome-binding factor A IstB_IS21 PF01695.12 KFM12286.1 - 0.14 11.5 0.0 0.31 10.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein F5_F8_type_C PF00754.20 KFM12287.1 - 7.1e-55 184.3 4.8 1.7e-27 95.8 0.5 2.6 2 0 0 2 2 2 2 F5/8 type C domain Cu-oxidase_3 PF07732.10 KFM12287.1 - 5.4e-17 61.6 0.0 3.1e-05 23.6 0.0 4.9 4 0 0 4 4 4 3 Multicopper oxidase Cu-oxidase_2 PF07731.9 KFM12287.1 - 4e-12 45.8 6.8 4.2e-08 32.8 0.8 4.6 5 0 0 5 5 5 3 Multicopper oxidase Muskelin_N PF06588.6 KFM12287.1 - 0.031 13.9 0.1 0.09 12.4 0.1 1.7 2 0 0 2 2 2 0 Muskelin N-terminus FUN14 PF04930.10 KFM12288.1 - 4.5e-33 113.4 3.8 5.5e-33 113.2 2.7 1.1 1 0 0 1 1 1 1 FUN14 family SH3BGR PF04908.10 KFM12288.1 - 0.046 13.6 0.0 3.5 7.6 0.0 2.2 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein DUF1903 PF08991.5 KFM12289.1 - 1.1e-12 47.9 5.5 1.2e-12 47.7 3.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) DUF1068 PF06364.7 KFM12289.1 - 0.086 12.4 1.7 0.097 12.2 1.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) TCL1_MTCP1 PF01840.12 KFM12290.1 - 1.6e-20 72.8 0.0 1.7e-20 72.7 0.0 1.0 1 0 0 1 1 1 1 TCL1/MTCP1 family Spectrin PF00435.16 KFM12291.1 - 4.3e-59 197.3 14.9 1.5e-19 70.2 0.3 4.4 4 0 0 4 4 4 4 Spectrin repeat CH PF00307.26 KFM12291.1 - 1.2e-41 141.1 0.4 1.4e-21 76.5 0.0 3.1 3 0 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFM12291.1 - 5.3e-12 45.2 0.1 1.6e-09 37.2 0.0 2.7 2 0 0 2 2 2 2 CAMSAP CH domain EF-hand_6 PF13405.1 KFM12291.1 - 0.0011 18.6 0.2 0.0034 17.1 0.2 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.27 KFM12291.1 - 0.0033 16.6 0.1 0.0087 15.3 0.1 1.8 1 0 0 1 1 1 1 EF hand Phage_int_SAM_5 PF13102.1 KFM12291.1 - 0.013 15.4 3.4 0.12 12.3 0.1 3.1 3 0 0 3 3 3 0 Phage integrase SAM-like domain XisI PF08869.6 KFM12291.1 - 0.04 14.0 1.1 0.12 12.4 0.8 1.8 1 0 0 1 1 1 0 XisI protein PAS_11 PF14598.1 KFM12292.1 - 4.5e-27 94.2 0.3 7.6e-23 80.5 0.1 2.6 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.6 KFM12292.1 - 1.2e-25 89.4 0.0 8.9e-20 70.5 0.0 2.4 2 0 0 2 2 2 2 PAS fold HIF-1a_CTAD PF08778.5 KFM12292.1 - 8e-21 73.2 0.4 2.1e-20 71.8 0.3 1.8 1 0 0 1 1 1 1 HIF-1 alpha C terminal transactivation domain HIF-1 PF11413.3 KFM12292.1 - 3.7e-18 64.4 0.7 8.3e-18 63.2 0.5 1.7 1 0 0 1 1 1 1 Hypoxia-inducible factor-1 PAS PF00989.19 KFM12292.1 - 1.8e-14 53.4 0.0 8.1e-07 28.8 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.1 KFM12292.1 - 2e-11 44.1 0.0 4.8e-06 26.9 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 KFM12292.1 - 2.7e-07 30.6 0.0 0.031 14.3 0.0 2.4 2 0 0 2 2 2 2 PAS fold HLH PF00010.21 KFM12292.1 - 0.075 12.7 0.3 0.18 11.5 0.2 1.7 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain TMEM247 PF15444.1 KFM12293.1 - 0.00084 19.2 0.1 0.00091 19.1 0.1 1.1 1 0 0 1 1 1 1 Transmembrane protein 247 Ras PF00071.17 KFM12294.1 - 3.8e-27 94.6 0.0 4.4e-27 94.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM12294.1 - 4.3e-06 27.2 0.0 7.5e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein DUF2330 PF10092.4 KFM12294.1 - 0.13 11.1 0.0 0.15 10.8 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2330) PIG-F PF06699.6 KFM12295.1 - 6.5e-52 176.2 16.9 7.8e-52 176.0 11.7 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Ferric_reduct PF01794.14 KFM12295.1 - 4.7 7.3 9.9 9.2 6.3 6.9 1.8 1 1 0 1 1 1 0 Ferric reductase like transmembrane component Bac_export_2 PF01312.14 KFM12295.1 - 6 5.6 5.4 4.7 6.0 2.9 1.3 1 1 0 1 1 1 0 FlhB HrpN YscU SpaS Family SH PF01445.12 KFM12295.1 - 8.1 6.1 7.4 6.2 6.5 1.0 2.7 1 1 1 2 2 2 0 Viral small hydrophobic protein Cript PF10235.4 KFM12296.1 - 1.4e-22 79.8 1.2 1.6e-22 79.6 0.8 1.0 1 0 0 1 1 1 1 Microtubule-associated protein CRIPT eIF3g PF12353.3 KFM12296.1 - 0.15 11.9 0.8 0.19 11.6 0.6 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G Cas_CXXC_CXXC PF09706.5 KFM12296.1 - 0.35 11.0 0.2 0.35 11.0 0.1 1.9 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) RVT_1 PF00078.22 KFM12297.1 - 0.026 13.9 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) SOCS PF12610.3 KFM12299.1 - 1.3e-19 70.2 3.5 6.2e-19 68.0 2.4 2.3 1 0 0 1 1 1 1 Suppressor of cytokine signalling SOCS_box PF07525.11 KFM12299.1 - 2.1e-12 46.6 0.2 4.6e-12 45.5 0.1 1.7 1 0 0 1 1 1 1 SOCS box SH2 PF00017.19 KFM12299.1 - 4e-09 36.1 0.0 9.8e-09 34.8 0.0 1.7 1 0 0 1 1 1 1 SH2 domain EF-hand_7 PF13499.1 KFM12300.1 - 5.4e-11 42.4 3.2 7.5e-11 42.0 2.2 1.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KFM12300.1 - 2.3e-08 33.2 0.3 0.0052 16.5 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 KFM12300.1 - 4.1e-07 28.8 0.2 0.0006 18.9 0.1 2.8 2 1 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 KFM12300.1 - 0.0043 16.3 3.1 0.013 14.8 0.6 2.6 2 1 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KFM12300.1 - 0.0048 16.4 1.6 0.023 14.2 0.1 2.5 2 2 0 2 2 2 1 EF-hand domain pair TPR_2 PF07719.12 KFM12301.1 - 5.9e-29 97.6 12.2 2.9e-05 23.6 0.1 10.4 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.1 KFM12301.1 - 4.4e-26 90.3 17.0 2.2e-07 30.4 0.0 7.0 5 2 2 7 7 7 3 TPR repeat TPR_16 PF13432.1 KFM12301.1 - 5.2e-21 74.7 11.5 6.8e-07 29.7 0.3 6.4 3 2 3 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.23 KFM12301.1 - 2.7e-18 64.7 15.4 1.6e-05 24.2 0.0 9.3 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFM12301.1 - 3e-18 64.4 5.2 0.0091 16.1 0.0 8.1 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 KFM12301.1 - 3.9e-18 64.3 19.5 0.063 13.9 0.0 11.0 6 2 5 11 11 11 6 Tetratricopeptide repeat TPR_12 PF13424.1 KFM12301.1 - 2.2e-16 59.5 25.4 2.4e-08 33.8 0.0 7.4 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFM12301.1 - 2.6e-14 51.8 8.2 0.0048 16.5 0.0 8.7 12 0 0 12 12 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFM12301.1 - 3.1e-11 43.4 16.6 0.00058 20.1 0.2 7.5 4 2 4 8 8 8 4 Tetratricopeptide repeat Apc3 PF12895.2 KFM12301.1 - 2e-09 37.4 10.2 0.065 13.3 0.6 5.7 4 2 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KFM12301.1 - 3.9e-09 36.2 13.2 0.035 13.9 2.5 5.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFM12301.1 - 5.8e-08 31.9 10.6 0.0082 15.8 0.0 8.0 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFM12301.1 - 1.6e-07 31.2 18.3 0.09 13.2 0.1 9.4 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_20 PF14561.1 KFM12301.1 - 3.8e-06 26.9 9.5 0.014 15.5 0.7 5.4 3 2 2 5 5 5 2 Tetratricopeptide repeat DUF3808 PF10300.4 KFM12301.1 - 2.2e-05 23.2 2.6 0.00081 18.0 0.1 3.1 2 1 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_15 PF13429.1 KFM12301.1 - 5.8e-05 22.2 8.6 0.00051 19.1 0.3 4.3 4 1 0 4 4 4 1 Tetratricopeptide repeat ChAPs PF09295.5 KFM12301.1 - 0.00023 20.0 2.5 0.86 8.2 0.0 3.2 3 0 0 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.1 KFM12301.1 - 0.0035 17.2 26.1 0.17 11.8 0.0 7.1 10 0 0 10 10 6 3 Tetratricopeptide repeat MIT PF04212.13 KFM12301.1 - 0.0044 16.8 5.3 2.1 8.2 0.0 5.4 6 0 0 6 6 6 1 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 KFM12301.1 - 0.0072 16.1 0.5 15 5.5 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat NARP1 PF12569.3 KFM12301.1 - 0.0088 14.8 1.8 3.2 6.4 0.0 3.0 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 PIN_2 PF10130.4 KFM12301.1 - 0.044 13.8 0.5 0.24 11.4 0.0 2.4 2 0 0 2 2 2 0 PIN domain TPR_21 PF09976.4 KFM12301.1 - 0.11 12.4 14.0 3.5 7.5 0.3 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 KFM12301.1 - 0.28 11.7 9.6 6.9 7.4 0.1 5.1 5 0 0 5 5 3 0 Tetratricopeptide repeat PPR PF01535.15 KFM12301.1 - 0.64 10.1 3.0 1.2e+02 2.9 0.0 4.8 5 0 0 5 5 3 0 PPR repeat EF-hand_1 PF00036.27 KFM12302.1 - 1.2e-43 143.1 10.0 2.9e-10 38.6 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KFM12302.1 - 7.1e-39 131.7 3.7 1.1e-21 76.6 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KFM12302.1 - 3.6e-36 122.5 9.8 3.7e-17 61.6 0.3 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 KFM12302.1 - 9.5e-32 106.0 5.4 9.8e-10 37.4 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KFM12302.1 - 2e-28 96.4 5.4 5.6e-07 28.6 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 KFM12302.1 - 6.8e-15 54.7 0.1 1.8e-08 34.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KFM12302.1 - 1.1e-09 37.9 0.4 3.6e-05 23.4 0.1 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KFM12302.1 - 1.5e-08 34.6 0.0 0.0011 18.9 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 KFM12302.1 - 1.1e-06 28.2 0.0 0.17 11.5 0.0 3.1 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 KFM12302.1 - 1.3e-06 28.2 0.5 6.7e-06 25.9 0.1 2.1 2 1 0 2 2 2 1 Ca2+ insensitive EF hand DUF1103 PF06513.6 KFM12302.1 - 0.00056 19.3 1.5 0.00065 19.1 1.0 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) TerB PF05099.8 KFM12302.1 - 0.001 18.8 0.5 0.18 11.5 0.0 2.1 1 1 1 2 2 2 1 Tellurite resistance protein TerB Caleosin PF05042.8 KFM12302.1 - 0.0037 16.8 0.1 0.1 12.1 0.1 2.6 1 1 0 1 1 1 1 Caleosin related protein RNA_pol_Rpb4 PF03874.11 KFM12302.1 - 0.014 15.4 1.7 1.8 8.6 0.1 2.4 3 0 0 3 3 2 0 RNA polymerase Rpb4 Poly_export PF02563.11 KFM12302.1 - 0.041 13.6 0.1 2.5 7.9 0.0 2.9 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein DUF3349 PF11829.3 KFM12302.1 - 0.059 13.8 0.4 11 6.5 0.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) MotA_activ PF09114.5 KFM12302.1 - 0.06 13.1 0.2 12 5.6 0.0 2.4 2 0 0 2 2 2 0 Transcription factor MotA, activation domain LNS2 PF08235.8 KFM12302.1 - 0.065 12.7 0.1 0.4 10.2 0.0 1.9 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) Tenui_NCP PF04876.7 KFM12302.1 - 0.085 12.4 0.1 0.52 9.8 0.0 1.9 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein DUF1880 PF08976.6 KFM12302.1 - 0.11 12.6 0.0 2 8.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) CMD PF02627.15 KFM12302.1 - 0.12 12.2 0.2 4.1 7.3 0.0 2.5 1 1 1 2 2 2 0 Carboxymuconolactone decarboxylase family Toprim_2 PF13155.1 KFM12302.1 - 0.19 12.0 0.7 19 5.6 0.1 2.5 1 1 2 3 3 3 0 Toprim-like VCBS PF13517.1 KFM12302.1 - 8.6 6.8 7.9 85 3.6 0.9 2.7 1 1 1 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 7tm_2 PF00002.19 KFM12303.1 - 4.4e-78 261.7 17.4 5.6e-78 261.3 12.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 KFM12303.1 - 8.4e-19 67.3 7.7 2.2e-18 65.9 5.3 1.8 1 0 0 1 1 1 1 Hormone receptor domain G-gamma PF00631.17 KFM12304.1 - 8.3e-11 41.4 0.0 8.8e-11 41.4 0.0 1.0 1 0 0 1 1 1 1 GGL domain Acyl-CoA_dh_1 PF00441.19 KFM12305.1 - 7.1e-39 133.2 0.0 1e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KFM12305.1 - 1.5e-19 69.2 2.1 2.4e-19 68.5 0.5 2.0 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KFM12305.1 - 1.6e-12 47.8 0.0 2.9e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KFM12305.1 - 4.8e-10 40.0 0.0 1.2e-09 38.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain DUF3011 PF11218.3 KFM12305.1 - 0.098 12.4 0.2 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3011) HpaB_N PF11794.3 KFM12305.1 - 0.16 11.3 0.0 0.55 9.5 0.0 1.9 2 1 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase N terminal SNARE PF05739.14 KFM12306.1 - 5.5e-12 45.1 0.3 6.5e-12 44.9 0.2 1.1 1 0 0 1 1 1 1 SNARE domain Sec20 PF03908.8 KFM12306.1 - 0.00022 20.8 0.2 0.0003 20.4 0.1 1.2 1 0 0 1 1 1 1 Sec20 Use1 PF09753.4 KFM12306.1 - 0.00034 20.1 0.0 0.00039 19.9 0.0 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF4407 PF14362.1 KFM12306.1 - 0.071 12.0 0.0 0.083 11.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Polysacc_synt_4 PF04669.8 KFM12306.1 - 0.11 11.9 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis Collagen PF01391.13 KFM12307.1 - 1.8e-164 533.3 671.1 4.4e-10 38.9 23.5 21.0 2 1 16 18 18 18 14 Collagen triple helix repeat (20 copies) COLFI PF01410.13 KFM12307.1 - 1.2e-94 315.7 0.0 1.4e-94 315.4 0.0 1.1 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Cas1_AcylT PF07779.7 KFM12308.1 - 5.3e-227 754.0 29.1 7.1e-227 753.6 20.2 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.1 KFM12308.1 - 1.5e-28 100.3 0.2 2.3e-28 99.7 0.1 1.3 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Sarcoglycan_2 PF05510.8 KFM12309.1 - 4.9e-162 538.6 0.0 5.6e-162 538.4 0.0 1.0 1 0 0 1 1 1 1 Sarcoglycan alpha/epsilon Het-C PF07217.6 KFM12309.1 - 0.056 11.6 0.0 0.079 11.1 0.0 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C SAM_2 PF07647.12 KFM12310.1 - 2.1e-16 59.5 0.9 4.6e-16 58.4 0.6 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDZ PF00595.19 KFM12310.1 - 6.3e-14 51.9 3.2 9.8e-14 51.3 1.4 2.0 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) SAM_1 PF00536.25 KFM12310.1 - 1.2e-13 51.0 1.1 2.7e-13 49.8 0.8 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 KFM12310.1 - 0.0081 15.8 0.1 0.027 14.2 0.1 1.8 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Arylesterase PF01731.15 KFM12311.1 - 1.7e-39 133.6 1.5 3.1e-39 132.8 1.1 1.4 1 0 0 1 1 1 1 Arylesterase SGL PF08450.7 KFM12311.1 - 5.1e-07 29.3 0.1 7.6e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 KFM12311.1 - 0.049 13.6 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Strictosidine synthase Glyco_hydro_42C PF08533.5 KFM12311.1 - 0.051 13.0 0.2 0.24 10.9 0.1 2.1 1 1 0 1 1 1 0 Beta-galactosidase C-terminal domain Ank_2 PF12796.2 KFM12312.1 - 2.5e-37 127.0 18.8 7.5e-18 64.6 0.9 4.5 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 KFM12312.1 - 4.4e-30 101.9 14.0 0.0003 20.4 0.2 7.9 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.1 KFM12312.1 - 1.4e-24 85.9 8.5 4.2e-08 33.4 0.2 7.1 2 1 5 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM12312.1 - 1e-17 63.7 13.4 0.001 19.2 0.1 5.2 5 2 1 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM12312.1 - 3.2e-16 57.7 17.6 0.022 14.9 0.4 8.4 9 1 0 9 9 9 4 Ankyrin repeat SOCS_box PF07525.11 KFM12312.1 - 1.5e-13 50.3 5.2 3.4e-13 49.2 3.6 1.6 1 0 0 1 1 1 1 SOCS box BCDHK_Adom3 PF10436.4 KFM12313.1 - 6e-50 168.9 0.0 8.7e-50 168.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KFM12313.1 - 2.3e-19 69.1 0.0 4e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KFM12313.1 - 0.0022 17.6 0.0 0.0042 16.7 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Adaptin_N PF01602.15 KFM12313.1 - 0.1 10.8 0.0 0.14 10.4 0.0 1.1 1 0 0 1 1 1 0 Adaptin N terminal region WD40 PF00400.27 KFM12314.1 - 7.7e-16 57.2 14.6 2.8e-06 26.9 0.2 7.2 8 0 0 8 8 8 6 WD domain, G-beta repeat Mito_carr PF00153.22 KFM12315.1 - 1.1e-73 243.0 1.0 6.5e-27 93.0 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 KFM12315.1 - 3.7e-09 35.2 1.1 0.047 13.0 0.1 5.3 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.1 KFM12315.1 - 1.7e-08 33.6 0.8 0.0048 16.6 0.0 5.5 6 0 0 6 6 6 2 EF-hand domain EF-hand_7 PF13499.1 KFM12315.1 - 3e-07 30.4 1.0 0.045 13.8 0.0 4.7 3 1 0 4 4 4 1 EF-hand domain pair EF-hand_8 PF13833.1 KFM12315.1 - 2.1e-06 27.2 1.6 0.17 11.5 0.0 4.4 5 0 0 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.1 KFM12315.1 - 4.3e-05 22.6 0.0 1.1 8.7 0.0 3.7 3 0 0 3 3 3 2 EF hand DSS1_SEM1 PF05160.8 KFM12316.1 - 1.6e-12 47.0 10.7 1.7e-12 46.9 7.4 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family Homeobox PF00046.24 KFM12317.1 - 4.1e-21 74.3 2.4 5.6e-21 73.9 1.7 1.2 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFM12317.1 - 0.017 14.8 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Homeobox KN domain Homez PF11569.3 KFM12317.1 - 0.04 12.9 0.1 0.073 12.1 0.1 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez DLL_N PF12413.3 KFM12318.1 - 9.3e-26 90.7 22.2 9.3e-26 90.7 15.4 2.0 2 0 0 2 2 2 1 Homeobox protein distal-less-like N terminal Homeobox PF00046.24 KFM12318.1 - 3.3e-05 23.4 0.0 5.6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Homeobox domain CEP19 PF14933.1 KFM12319.1 - 0.038 14.2 1.2 0.042 14.1 0.8 1.1 1 0 0 1 1 1 0 CEP19-like protein Tup_N PF08581.5 KFM12319.1 - 0.16 12.1 2.1 0.19 11.9 1.5 1.2 1 0 0 1 1 1 0 Tup N-terminal Asn_synthase PF00733.16 KFM12320.1 - 1.7e-63 214.5 0.0 2.2e-63 214.1 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KFM12320.1 - 5.6e-26 90.7 0.0 1e-25 89.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KFM12320.1 - 5.4e-21 74.9 0.0 1.4e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 KFM12320.1 - 9.5e-09 34.4 0.0 0.00014 20.6 0.0 2.4 1 1 0 2 2 2 2 Glutamine amidotransferases class-II DUF3700 PF12481.3 KFM12320.1 - 1.2e-07 31.2 0.0 2.4e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 KFM12320.1 - 0.015 14.2 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 NAD synthase tRNA_Me_trans PF03054.11 KFM12320.1 - 0.018 13.5 0.0 0.027 13.0 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase QueC PF06508.8 KFM12320.1 - 0.021 14.1 0.0 0.036 13.3 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Fringe PF02434.11 KFM12321.1 - 7.7e-15 54.7 0.9 4e-14 52.4 0.7 1.9 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.16 KFM12321.1 - 2.6e-09 36.9 0.6 4.2e-05 23.2 0.2 2.2 1 1 1 2 2 2 2 Galactosyltransferase Rep_fac-A_3 PF08661.6 KFM12323.1 - 7.4e-20 70.8 0.0 8.1e-20 70.7 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 FAM117 PF15388.1 KFM12325.1 - 5.4e-122 407.0 23.0 5.4e-122 407.0 16.0 1.9 1 1 1 2 2 2 1 Protein Family FAM117 Arfaptin PF06456.8 KFM12326.1 - 5.4e-89 297.4 11.9 7.8e-89 296.9 8.2 1.2 1 0 0 1 1 1 1 Arfaptin-like domain ICA69 PF04629.9 KFM12326.1 - 1.6e-58 198.5 18.2 1.3e-57 195.5 10.0 2.5 2 1 0 2 2 2 1 Islet cell autoantigen ICA69, C-terminal domain BAR_2 PF10455.4 KFM12326.1 - 0.0012 17.8 2.8 0.0016 17.4 1.4 1.6 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Neurexophilin PF06312.7 KFM12327.1 - 1.1e-112 374.5 3.2 1.4e-112 374.2 2.2 1.1 1 0 0 1 1 1 1 Neurexophilin NigD PF12667.2 KFM12327.1 - 0.031 14.0 0.3 0.079 12.7 0.0 1.7 1 1 1 2 2 2 0 NigD-like protein Filamin PF00630.14 KFM12327.1 - 0.042 14.3 0.0 0.14 12.7 0.0 1.9 2 0 0 2 2 2 0 Filamin/ABP280 repeat Nepo_coat_C PF03688.9 KFM12327.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Nepovirus coat protein, C-terminal domain TSP_1 PF00090.14 KFM12328.1 - 1.8e-33 114.4 144.8 4.9e-13 48.9 4.8 15.2 16 1 0 16 16 16 11 Thrombospondin type 1 domain Sec7 PF01369.15 KFM12329.1 - 4.1e-68 228.8 0.1 6e-68 228.2 0.1 1.2 1 0 0 1 1 1 1 Sec7 domain PH PF00169.24 KFM12329.1 - 2e-24 85.7 0.0 3.6e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KFM12329.1 - 2.5e-06 27.7 2.9 4.7e-06 26.8 0.5 2.5 2 1 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.1 KFM12329.1 - 0.015 15.1 0.0 0.058 13.2 0.0 2.0 1 1 0 1 1 1 0 PH domain PH_8 PF15409.1 KFM12329.1 - 0.035 14.1 0.0 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain UCH PF00443.24 KFM12330.1 - 2.6e-55 187.4 2.0 2.6e-55 187.4 1.4 2.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFM12330.1 - 3.6e-25 89.0 0.9 3.6e-25 89.0 0.6 3.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Pkinase PF00069.20 KFM12331.1 - 5.6e-45 153.5 1.2 2.8e-29 102.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFM12331.1 - 1.6e-26 92.9 0.4 1.8e-25 89.4 0.3 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase TMF_TATA_bd PF12325.3 KFM12331.1 - 0.023 14.4 3.3 0.063 13.0 2.3 1.8 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF641 PF04859.7 KFM12331.1 - 0.023 14.4 0.9 0.048 13.4 0.7 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) P4Ha_N PF08336.6 KFM12331.1 - 0.041 13.6 1.0 0.11 12.3 0.7 1.7 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region SlyX PF04102.7 KFM12331.1 - 0.063 13.6 4.1 0.054 13.8 1.4 2.0 2 0 0 2 2 2 0 SlyX FliJ PF02050.11 KFM12331.1 - 0.065 13.2 4.4 0.14 12.1 3.1 1.5 1 0 0 1 1 1 0 Flagellar FliJ protein DivIC PF04977.10 KFM12331.1 - 0.85 9.1 4.5 0.62 9.5 1.5 1.9 2 0 0 2 2 2 0 Septum formation initiator GST_C_3 PF14497.1 KFM12332.1 - 8.8e-07 29.3 0.3 2e-06 28.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KFM12332.1 - 2.5e-06 27.4 0.0 5.8e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFM12332.1 - 1.3e-05 24.9 0.0 2.7e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MutL_C PF08676.6 KFM12333.1 - 1.8e-28 98.9 0.0 5e-28 97.5 0.0 1.8 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 KFM12333.1 - 2.5e-23 81.7 3.3 2.8e-23 81.6 0.0 2.6 3 0 0 3 3 3 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KFM12333.1 - 1.3e-13 50.8 0.0 3.4e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KFM12333.1 - 6.2e-11 41.9 0.1 1.7e-10 40.5 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MORN PF02493.15 KFM12334.1 - 1.6e-16 58.9 32.7 6.8e-08 31.7 0.6 5.3 5 1 0 5 5 5 5 MORN repeat DUF3811 PF11656.3 KFM12335.1 - 1.9 8.5 5.7 0.43 10.6 1.6 1.8 2 0 0 2 2 2 0 YjbD family (DUF3811) DUF1712 PF08217.6 KFM12336.1 - 1.6e-100 337.1 6.2 1.7e-90 304.0 0.2 2.1 1 1 1 2 2 2 2 Fungal domain of unknown function (DUF1712) EF-hand_1 PF00036.27 KFM12338.1 - 2.1e-14 51.6 1.6 6.5e-07 28.2 0.4 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 KFM12338.1 - 4.2e-13 49.2 0.3 6.8e-13 48.5 0.2 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KFM12338.1 - 1e-12 46.7 0.3 1.3e-06 27.7 0.1 2.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 KFM12338.1 - 8.7e-11 40.6 2.1 4.4e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 KFM12338.1 - 2.9e-10 39.5 0.5 1.2e-05 24.8 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_10 PF14788.1 KFM12338.1 - 0.0069 16.0 1.3 0.12 12.0 0.4 2.3 2 0 0 2 2 2 1 EF hand Toprim_2 PF13155.1 KFM12338.1 - 0.031 14.5 0.1 7.5 6.9 0.0 2.1 1 1 1 2 2 2 0 Toprim-like SPARC_Ca_bdg PF10591.4 KFM12338.1 - 0.094 12.7 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_1 PF00036.27 KFM12339.1 - 0.00024 20.2 2.3 0.22 10.8 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KFM12339.1 - 0.00046 19.8 1.1 0.16 11.9 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 KFM12339.1 - 0.0036 17.4 0.5 0.013 15.6 0.3 1.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KFM12339.1 - 0.16 11.5 0.7 0.54 9.9 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.1 KFM12339.1 - 6.6 6.2 6.5 0.97 8.9 0.7 2.3 2 1 0 2 2 2 0 EF hand EF-hand_1 PF00036.27 KFM12340.1 - 9e-14 49.6 2.1 2.6e-06 26.3 0.4 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KFM12340.1 - 3.8e-12 44.9 1.3 2.7e-06 26.7 0.1 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 KFM12340.1 - 5.2e-11 42.5 0.1 7.7e-11 41.9 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 KFM12340.1 - 6e-11 41.1 3.1 6.5e-05 22.1 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 KFM12340.1 - 1.3e-09 37.5 0.7 3.9e-08 32.7 0.1 2.1 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFM12340.1 - 0.0049 16.8 0.0 0.006 16.6 0.0 1.3 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.5 KFM12340.1 - 0.11 12.4 1.8 0.19 11.7 0.0 2.1 2 1 0 2 2 2 0 Ca2+ insensitive EF hand EF-hand_10 PF14788.1 KFM12340.1 - 0.2 11.3 1.1 0.56 9.9 0.2 2.1 2 1 1 3 3 3 0 EF hand Pkinase_Tyr PF07714.12 KFM12341.1 - 2.1e-54 184.3 0.0 3.2e-54 183.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM12341.1 - 2.4e-30 105.5 0.0 5.3e-30 104.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain DUF3270 PF11674.3 KFM12341.1 - 0.66 10.0 2.3 2.3 8.2 1.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) HLH PF00010.21 KFM12342.1 - 1.2e-16 60.1 3.7 1.2e-16 60.1 2.6 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Apis_Csd PF11671.3 KFM12342.1 - 0.059 13.1 1.2 0.1 12.4 0.8 1.6 1 1 0 1 1 1 0 Complementary sex determiner protein RepB PF07506.6 KFM12342.1 - 0.067 13.0 2.7 0.094 12.5 1.9 1.3 1 0 0 1 1 1 0 RepB plasmid partitioning protein Ribosomal_L19e PF01280.15 KFM12342.1 - 0.53 10.0 12.3 0.5 10.1 7.5 1.7 1 1 1 2 2 2 0 Ribosomal protein L19e Hyd_WA PF06462.7 KFM12343.1 - 9.7e-85 277.8 59.1 1.4e-14 53.4 1.9 12.1 12 0 0 12 12 12 10 Propeller Pex24p PF06398.6 KFM12343.1 - 6.7e-22 77.7 22.2 1.9e-11 43.3 3.8 2.2 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin DUF2367 PF10164.4 KFM12344.1 - 3.1e-31 107.1 5.2 3.5e-31 106.9 3.6 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) DUF2636 PF11120.3 KFM12344.1 - 0.0064 15.9 1.5 0.0098 15.3 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2636) zf-ribbon_3 PF13248.1 KFM12344.1 - 0.026 13.7 5.0 0.045 12.9 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_4 PF14570.1 KFM12344.1 - 0.037 13.6 1.3 4.1 7.0 0.2 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain UPF0547 PF10571.4 KFM12344.1 - 0.046 13.4 5.9 0.21 11.2 4.1 2.0 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 zinc_ribbon_2 PF13240.1 KFM12344.1 - 0.065 12.7 1.4 0.32 10.5 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_3 PF14369.1 KFM12344.1 - 0.091 12.7 0.6 15 5.7 0.1 2.4 2 0 0 2 2 2 0 zinc-finger DUF1936 PF09151.5 KFM12344.1 - 0.18 11.3 4.9 0.96 9.0 1.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) zf-nanos PF05741.8 KFM12344.1 - 0.29 11.1 0.2 0.29 11.1 0.2 1.6 2 0 0 2 2 2 0 Nanos RNA binding domain zinc_ribbon_5 PF13719.1 KFM12344.1 - 1 8.9 3.6 1 8.9 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KFM12344.1 - 1.2 8.8 3.4 1.2 8.8 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-NADH-PPase PF09297.6 KFM12344.1 - 2.5 7.6 6.7 0.53 9.8 0.8 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-C3HC4_3 PF13920.1 KFM12344.1 - 2.9 7.6 5.3 32 4.3 0.0 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF35_N PF12172.3 KFM12344.1 - 6.2 6.8 8.0 7.4 6.6 2.4 2.7 2 1 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) IMD PF08397.6 KFM12345.1 - 2.1e-90 301.8 5.3 2.6e-90 301.5 3.7 1.1 1 0 0 1 1 1 1 IRSp53/MIM homology domain SH3_9 PF14604.1 KFM12345.1 - 4.1e-11 42.2 0.0 6.9e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFM12345.1 - 8.5e-08 31.5 0.0 1.6e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM12345.1 - 7e-07 28.5 0.0 1.4e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain DUF3510 PF12022.3 KFM12345.1 - 0.0062 16.6 4.2 0.015 15.4 2.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) T2SF PF00482.18 KFM12345.1 - 0.047 13.5 0.1 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F NusB PF01029.13 KFM12345.1 - 0.39 10.7 2.6 0.71 9.8 1.8 1.3 1 0 0 1 1 1 0 NusB family Pentaxin PF00354.12 KFM12346.1 - 9e-38 129.6 0.0 1.3e-37 129.1 0.0 1.2 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.1 KFM12346.1 - 7.3e-15 55.5 0.0 1.1e-14 55.0 0.0 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily SlyX PF04102.7 KFM12346.1 - 0.00045 20.5 6.6 0.55 10.6 0.1 3.7 3 1 0 3 3 3 2 SlyX Laminin_G_2 PF02210.19 KFM12346.1 - 0.0042 17.1 0.0 0.0078 16.2 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain Atg14 PF10186.4 KFM12346.1 - 0.067 12.1 6.6 0.74 8.7 0.3 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Syntaxin PF00804.20 KFM12346.1 - 0.085 13.0 1.8 0.52 10.5 0.7 2.3 1 1 2 3 3 3 0 Syntaxin FlxA PF14282.1 KFM12346.1 - 0.29 11.1 1.4 0.38 10.7 0.1 1.7 2 0 0 2 2 2 0 FlxA-like protein GOLGA2L5 PF15070.1 KFM12346.1 - 0.3 9.5 8.8 0.46 8.9 6.0 1.3 1 1 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 PspB PF06667.7 KFM12346.1 - 0.62 10.0 0.1 0.62 10.0 0.0 2.3 2 1 0 2 2 2 0 Phage shock protein B GrpE PF01025.14 KFM12346.1 - 1.9 8.0 5.4 5.2 6.5 3.8 1.8 1 1 0 1 1 1 0 GrpE Pox_A_type_inc PF04508.7 KFM12346.1 - 2.2 8.2 14.9 11 6.0 0.1 4.8 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat bZIP_1 PF00170.16 KFM12346.1 - 2.7 8.0 9.4 9.7 6.2 0.8 3.5 3 1 1 4 4 4 0 bZIP transcription factor Baculo_PEP_C PF04513.7 KFM12346.1 - 3 7.6 5.1 1.3 8.8 1.2 2.0 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin-6_N PF09177.6 KFM12346.1 - 3.2 8.2 5.3 6.5 7.2 0.4 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal CorA PF01544.13 KFM12346.1 - 4.9 6.0 6.7 3.4 6.6 3.2 1.6 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein PKD PF00801.15 KFM12347.1 - 1.5e-07 31.0 0.2 0.025 14.3 0.0 3.4 3 0 0 3 3 3 3 PKD domain FAT PF02259.18 KFM12348.1 - 4.1e-67 226.6 10.7 1.1e-66 225.2 6.7 2.4 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 KFM12348.1 - 8.7e-19 67.9 0.1 2.7e-18 66.2 0.1 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 KFM12348.1 - 0.0001 21.6 0.1 0.00038 19.8 0.1 2.1 1 0 0 1 1 1 1 FATC domain TPR_2 PF07719.12 KFM12348.1 - 0.77 9.8 5.5 4.4 7.4 0.6 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFM12348.1 - 1.8 8.5 6.9 20 5.2 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1193 PF06702.7 KFM12350.1 - 7.7e-114 378.6 0.3 1e-113 378.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1193) Fork_head PF00250.13 KFM12351.1 - 3.3e-38 129.6 0.2 4e-38 129.3 0.2 1.0 1 0 0 1 1 1 1 Fork head domain PDGF PF00341.12 KFM12352.1 - 2.7e-21 75.4 9.9 4.1e-21 74.8 6.9 1.3 1 0 0 1 1 1 1 PDGF/VEGF domain PDGF_N PF04692.8 KFM12352.1 - 3.4e-09 37.0 1.2 4.6e-09 36.6 0.1 1.8 2 0 0 2 2 2 1 Platelet-derived growth factor, N terminal region cNMP_binding PF00027.24 KFM12353.1 - 6e-45 150.9 0.1 3.7e-21 74.7 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 KFM12353.1 - 1.1e-13 50.3 0.1 2.1e-13 49.4 0.1 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit GXGXG PF01493.14 KFM12353.1 - 0.0056 15.6 0.1 0.14 11.1 0.0 2.1 2 0 0 2 2 2 1 GXGXG motif HEAT_2 PF13646.1 KFM12354.1 - 5.1e-15 55.5 0.1 6.8e-05 23.0 0.0 6.2 3 2 2 6 6 6 4 HEAT repeats Vac14_Fab1_bd PF12755.2 KFM12354.1 - 3.8e-10 40.0 1.6 0.059 13.7 0.0 5.6 4 2 2 6 6 6 4 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KFM12354.1 - 3.5e-05 24.1 15.4 1.6 9.3 0.0 8.2 7 1 2 9 9 9 2 HEAT-like repeat DUF3535 PF12054.3 KFM12354.1 - 0.0011 17.6 0.1 0.0066 15.1 0.0 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF3535) IFRD PF05004.8 KFM12354.1 - 0.0011 18.1 6.7 0.0027 16.8 0.0 3.6 3 1 0 4 4 4 1 Interferon-related developmental regulator (IFRD) CLASP_N PF12348.3 KFM12354.1 - 0.0027 17.1 13.2 0.024 13.9 0.2 4.5 4 2 1 5 5 5 2 CLASP N terminal HEAT PF02985.17 KFM12354.1 - 0.003 17.4 35.2 0.54 10.4 0.0 10.7 13 0 0 13 13 13 3 HEAT repeat Sad1_UNC PF07738.8 KFM12355.1 - 1.1e-43 148.2 0.0 2.5e-43 147.1 0.0 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal MRP PF09387.5 KFM12355.1 - 4.2e-19 69.0 4.7 3.4e-18 66.0 3.3 2.1 1 1 0 1 1 1 1 Mitochondrial RNA binding protein MRP zf-C4pol PF14260.1 KFM12355.1 - 4 7.5 7.1 2.7 8.0 0.1 3.6 3 1 1 4 4 4 0 C4-type zinc-finger of DNA polymerase delta DUF410 PF04190.8 KFM12356.1 - 1.3e-87 293.6 0.1 8e-86 287.7 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF410) ArfGap PF01412.13 KFM12357.1 - 7e-27 93.5 0.1 1.2e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.24 KFM12357.1 - 7e-16 58.3 0.4 1.4e-08 34.8 0.2 2.9 2 1 0 2 2 2 2 PH domain PH_11 PF15413.1 KFM12357.1 - 2.7e-14 53.3 0.3 2.9e-09 37.1 0.1 3.1 2 1 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 KFM12357.1 - 6.8e-05 22.8 3.8 0.081 13.0 0.1 3.0 3 1 0 3 3 3 2 Pleckstrin homology domain PH_3 PF14593.1 KFM12357.1 - 0.0014 18.5 0.2 0.33 10.8 0.0 2.8 3 0 0 3 3 3 1 PH domain Mcp5_PH PF12814.2 KFM12357.1 - 0.069 13.0 0.0 0.21 11.5 0.0 1.9 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology p450 PF00067.17 KFM12359.1 - 7.2e-122 407.2 0.4 8e-122 407.0 0.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KFM12360.1 - 1.7e-122 409.2 0.7 1.9e-122 409.1 0.5 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KFM12361.1 - 4.4e-128 427.6 0.9 4.9e-128 427.5 0.6 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2373 PF10180.4 KFM12362.1 - 5.6e-22 77.0 0.3 8.2e-22 76.5 0.2 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) 7tm_1 PF00001.16 KFM12363.1 - 1.3e-16 60.5 18.0 2e-16 59.9 12.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Col_cuticle_N PF01484.12 KFM12363.1 - 0.73 9.5 0.0 0.73 9.5 0.0 3.2 4 0 0 4 4 4 0 Nematode cuticle collagen N-terminal domain 7tm_1 PF00001.16 KFM12365.1 - 1.5e-46 158.6 16.9 2e-46 158.2 11.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM12365.1 - 2.7e-05 23.4 16.1 3.5e-05 23.0 11.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx zf-AN1 PF01428.11 KFM12366.1 - 2.2e-21 75.4 23.3 3.1e-12 46.1 6.6 2.8 3 0 0 3 3 3 2 AN1-like Zinc finger FYVE PF01363.16 KFM12366.1 - 0.018 14.9 3.1 0.018 14.9 2.2 2.5 2 1 0 2 2 2 0 FYVE zinc finger IBR PF01485.16 KFM12366.1 - 0.19 11.6 24.4 2 8.3 10.7 3.8 1 1 1 2 2 2 0 IBR domain zf-dskA_traR PF01258.12 KFM12366.1 - 0.5 10.1 5.7 35 4.2 0.1 3.5 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger zf-C3HC PF07967.8 KFM12366.1 - 0.5 10.1 7.7 0.36 10.5 0.8 2.3 2 0 0 2 2 2 0 C3HC zinc finger-like zf-C4_Topoisom PF01396.14 KFM12366.1 - 1.8 8.1 10.8 9.2 5.8 0.6 3.9 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger DUF3585 PF12130.3 KFM12367.1 - 3.9e-46 156.4 23.4 6.4e-46 155.7 16.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3585) CH PF00307.26 KFM12367.1 - 5e-06 26.5 0.1 1.4e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain LIM PF00412.17 KFM12367.1 - 1.4e-05 25.0 2.7 2.8e-05 24.1 1.9 1.5 1 0 0 1 1 1 1 LIM domain DUF3677 PF12432.3 KFM12368.1 - 2.8e-29 101.3 2.0 2.8e-29 101.3 1.4 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3677) UNC45-central PF11701.3 KFM12368.1 - 0.19 11.3 4.7 2.2 7.9 0.1 4.1 4 0 0 4 4 4 0 Myosin-binding striated muscle assembly central Glyco_hydro_31 PF01055.21 KFM12369.1 - 6.2e-143 476.8 0.0 7.6e-143 476.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KFM12369.1 - 7.6e-08 32.1 0.0 2.3e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like bZIP_Maf PF03131.12 KFM12370.1 - 1.1e-34 118.5 12.5 1.4e-34 118.2 8.7 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor DivIC PF04977.10 KFM12370.1 - 0.00019 20.8 5.4 0.00019 20.8 3.7 2.2 1 1 1 2 2 2 1 Septum formation initiator bZIP_1 PF00170.16 KFM12370.1 - 0.0061 16.4 16.7 0.14 12.1 11.5 2.4 1 1 0 1 1 1 1 bZIP transcription factor Spc24 PF08286.6 KFM12370.1 - 0.012 15.2 0.4 0.012 15.2 0.3 1.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF1192 PF06698.6 KFM12370.1 - 0.018 14.8 8.2 0.048 13.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF2046 PF09755.4 KFM12370.1 - 0.019 13.8 6.2 0.028 13.3 0.8 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) DUF972 PF06156.8 KFM12370.1 - 0.034 14.4 2.2 0.034 14.4 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Tox-ODYAM1 PF15642.1 KFM12370.1 - 0.041 12.5 2.1 0.048 12.3 1.4 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus HGTP_anticodon2 PF12745.2 KFM12370.1 - 0.067 12.3 3.9 0.075 12.1 2.7 1.0 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Mnd1 PF03962.10 KFM12370.1 - 0.081 12.5 2.4 0.11 12.1 1.7 1.3 1 0 0 1 1 1 0 Mnd1 family DUF342 PF03961.8 KFM12370.1 - 0.082 11.3 2.6 0.087 11.2 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 KFM12370.1 - 0.16 10.9 6.4 0.2 10.6 4.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 bZIP_2 PF07716.10 KFM12370.1 - 0.23 11.3 15.9 0.24 11.2 9.3 2.3 1 1 1 2 2 2 0 Basic region leucine zipper DUF4164 PF13747.1 KFM12370.1 - 0.42 10.7 8.4 0.096 12.8 3.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Uds1 PF15456.1 KFM12370.1 - 0.48 10.4 8.0 1.3 9.0 1.0 2.3 1 1 1 2 2 2 0 Up-regulated During Septation Microtub_assoc PF07989.6 KFM12370.1 - 0.6 9.9 8.3 1.8 8.4 5.8 1.8 1 1 0 1 1 1 0 Microtubule associated IncA PF04156.9 KFM12370.1 - 0.97 8.9 9.8 3.7 7.1 6.8 1.8 1 1 0 1 1 1 0 IncA protein Mst1_SARAH PF11629.3 KFM12370.1 - 1.3 8.9 6.1 14 5.6 0.1 2.7 2 1 0 2 2 2 0 C terminal SARAH domain of Mst1 HALZ PF02183.13 KFM12370.1 - 1.9 8.2 9.1 0.94 9.2 3.3 2.6 2 1 0 2 2 2 0 Homeobox associated leucine zipper DUF904 PF06005.7 KFM12370.1 - 5.9 7.2 12.2 29 5.0 8.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF4140 PF13600.1 KFM12370.1 - 6.4 7.2 9.3 5.6 7.4 3.0 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) XkdW PF09636.5 KFM12370.1 - 7.1 6.5 6.4 5.1 7.0 1.7 2.1 1 1 1 2 2 2 0 XkdW protein Solute_trans_a PF03619.11 KFM12371.1 - 1.3e-98 329.6 21.6 1.7e-98 329.3 15.0 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF1422 PF07226.6 KFM12371.1 - 0.045 13.4 0.1 0.045 13.4 0.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1422) DUF2372 PF10178.4 KFM12372.1 - 9.8e-31 105.7 0.1 1.3e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2372) LRR_8 PF13855.1 KFM12373.1 - 1.4e-24 85.6 5.9 1.2e-14 53.7 0.2 3.4 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KFM12373.1 - 2e-13 49.5 10.1 2.9e-05 23.5 0.3 3.5 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM12373.1 - 3.4e-09 35.4 8.1 0.39 10.9 0.0 5.8 5 0 0 5 5 5 4 Leucine Rich Repeat LRR_5 PF13306.1 KFM12373.1 - 1.9e-08 34.0 0.1 5.7e-08 32.5 0.0 1.6 1 1 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_6 PF13516.1 KFM12373.1 - 4.5e-06 26.1 7.5 3.9 7.8 0.1 5.9 4 1 1 5 5 5 3 Leucine Rich repeat LRR_7 PF13504.1 KFM12373.1 - 0.44 10.9 9.1 13 6.5 0.2 5.2 5 1 0 5 5 5 0 Leucine rich repeat MAD PF05557.8 KFM12374.1 - 9.8e-198 658.6 99.0 1.1e-197 658.4 68.6 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein TSC22 PF01166.13 KFM12374.1 - 0.017 15.0 4.9 0.017 15.0 3.4 9.6 5 3 4 10 10 10 0 TSC-22/dip/bun family AhpC-TSA PF00578.16 KFM12374.1 - 0.021 14.5 0.3 2.6 7.7 0.0 2.9 2 0 0 2 2 2 0 AhpC/TSA family FtsJ PF01728.14 KFM12375.1 - 2.2e-51 174.4 0.0 2.7e-51 174.1 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 KFM12375.1 - 0.016 14.9 0.0 0.09 12.4 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain NUDIX PF00293.23 KFM12376.1 - 2.5e-17 62.7 0.0 3.3e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 KFM12376.1 - 0.011 15.1 0.1 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 NUDIX domain PX PF00787.19 KFM12377.1 - 1.8e-21 76.0 2.1 1.8e-21 76.0 1.5 2.0 2 1 0 2 2 2 1 PX domain EPSP_synthase PF00275.15 KFM12377.1 - 0.12 10.7 0.0 0.2 10.0 0.0 1.2 1 0 0 1 1 1 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) TMPIT PF07851.8 KFM12377.1 - 0.39 9.7 6.5 0.2 10.6 3.0 1.5 2 0 0 2 2 2 0 TMPIT-like protein eIF2A PF08662.6 KFM12378.1 - 5.8e-73 244.7 7.5 4.3e-67 225.5 1.7 4.4 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 KFM12378.1 - 1.2e-06 28.0 0.1 3.1e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM12378.1 - 4.7e-05 23.1 0.1 0.00015 21.5 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IKI3 PF04762.7 KFM12378.1 - 0.0011 16.8 0.3 0.33 8.7 0.1 2.4 1 1 1 2 2 2 2 IKI3 family WD40 PF00400.27 KFM12378.1 - 0.0054 16.5 4.0 27 4.8 0.0 5.8 7 0 0 7 7 7 0 WD domain, G-beta repeat RRM_6 PF14259.1 KFM12378.1 - 0.0067 16.3 0.1 0.034 14.1 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 KFM12378.1 - 0.071 12.8 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Sulfotransfer_2 PF03567.9 KFM12379.1 - 6e-64 216.1 3.5 7e-64 215.9 1.4 1.7 2 0 0 2 2 2 1 Sulfotransferase family 7tm_1 PF00001.16 KFM12380.1 - 6.3e-47 159.8 17.1 7.2e-47 159.6 11.9 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 KFM12380.1 - 0.0057 15.8 9.0 0.013 14.6 6.0 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Serpentine_r_xa PF03383.10 KFM12380.1 - 0.0072 16.0 2.4 0.0072 16.0 1.7 2.1 1 1 1 2 2 2 1 Caenorhabditis serpentine receptor-like protein, class xa 7TM_GPCR_Srx PF10328.4 KFM12380.1 - 0.014 14.5 17.0 0.032 13.3 11.8 1.6 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx DUF1426 PF07234.6 KFM12380.1 - 0.018 14.7 0.2 0.1 12.3 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1426) Git3 PF11710.3 KFM12380.1 - 8.3 5.9 13.5 0.29 10.6 5.2 1.7 2 1 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 Gal-bind_lectin PF00337.17 KFM12381.1 - 3.7e-36 123.3 0.2 4.1e-36 123.2 0.1 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin Fringe PF02434.11 KFM12382.1 - 4.3e-107 357.0 0.0 4.8e-107 356.8 0.0 1.0 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.16 KFM12382.1 - 0.00028 20.5 0.0 0.00041 20.0 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Glyco_tranf_2_4 PF13704.1 KFM12382.1 - 0.08 13.2 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 Tweety PF04906.8 KFM12383.1 - 1.9e-171 569.9 10.9 2.4e-171 569.6 7.5 1.0 1 0 0 1 1 1 1 Tweety DUF4131 PF13567.1 KFM12383.1 - 0.00066 19.1 5.4 0.012 15.0 0.3 2.5 3 0 0 3 3 3 2 Domain of unknown function (DUF4131) DUF2721 PF11026.3 KFM12383.1 - 0.029 14.0 0.1 0.029 14.0 0.1 2.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2721) Prominin PF05478.6 KFM12383.1 - 0.072 10.6 13.4 0.021 12.4 1.1 2.8 2 1 0 3 3 3 0 Prominin Pex24p PF06398.6 KFM12383.1 - 0.097 11.4 0.1 0.89 8.2 0.0 2.3 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin DUF2207 PF09972.4 KFM12383.1 - 0.27 9.7 2.4 1.3 7.4 0.8 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) SlyX PF04102.7 KFM12384.1 - 0.034 14.5 16.4 0.037 14.4 0.3 3.8 2 1 1 3 3 3 0 SlyX Phage_GP20 PF06810.6 KFM12384.1 - 0.039 13.4 24.8 1.1 8.7 4.1 3.2 1 1 2 3 3 3 0 Phage minor structural protein GP20 CM1 PF03026.10 KFM12384.1 - 0.043 12.9 0.2 0.067 12.2 0.1 1.2 1 0 0 1 1 1 0 Influenza C virus M1 protein DivIC PF04977.10 KFM12384.1 - 0.053 13.0 19.6 0.51 9.8 0.6 3.9 3 1 1 4 4 4 0 Septum formation initiator DUF972 PF06156.8 KFM12384.1 - 0.1 12.9 25.8 0.24 11.7 3.6 3.5 1 1 1 3 3 3 0 Protein of unknown function (DUF972) APG6 PF04111.7 KFM12384.1 - 0.11 11.5 23.2 0.6 9.0 4.1 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 Allexi_40kDa PF05549.6 KFM12384.1 - 0.14 11.3 7.4 0.052 12.8 2.9 1.8 1 1 0 1 1 1 0 Allexivirus 40kDa protein TBPIP PF07106.8 KFM12384.1 - 1.4 8.4 24.5 1.3 8.5 2.3 3.2 1 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Tropomyosin_1 PF12718.2 KFM12384.1 - 1.6 8.6 28.0 2.1 8.1 2.4 2.8 1 1 1 2 2 2 0 Tropomyosin like CENP-Q PF13094.1 KFM12384.1 - 1.6 8.7 25.6 0.17 11.8 1.8 3.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Seryl_tRNA_N PF02403.17 KFM12384.1 - 2.3 8.2 23.5 1.8 8.6 2.7 3.3 1 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain ATG16 PF08614.6 KFM12384.1 - 2.8 7.7 27.1 0.26 11.1 3.9 3.2 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) MbeD_MobD PF04899.7 KFM12384.1 - 2.9 7.8 6.7 2.2 8.2 0.5 3.1 3 0 0 3 3 3 0 MbeD/MobD like IncA PF04156.9 KFM12384.1 - 3.5 7.1 22.6 9.8 5.7 4.8 2.5 1 1 1 2 2 2 0 IncA protein DUF3166 PF11365.3 KFM12384.1 - 4.2 7.8 15.7 6.7 7.2 3.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3166) HEAT PF02985.17 KFM12385.1 - 5.2e-07 29.2 11.6 0.01 15.8 0.0 6.2 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.1 KFM12385.1 - 1.2e-06 28.7 0.0 0.00033 20.8 0.0 3.9 3 2 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.1 KFM12385.1 - 1.6e-05 25.2 0.6 0.16 12.4 0.1 4.9 4 1 0 4 4 4 2 HEAT-like repeat Cohesin_HEAT PF12765.2 KFM12385.1 - 0.0028 17.5 0.5 0.29 11.1 0.0 3.4 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion TspO_MBR PF03073.10 KFM12385.1 - 0.0084 15.6 0.3 0.016 14.7 0.2 1.4 1 0 0 1 1 1 1 TspO/MBR family DUF2435 PF10363.4 KFM12385.1 - 0.052 13.4 0.0 0.24 11.3 0.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2435) Peptidase_M54 PF07998.6 KFM12386.1 - 2.1e-05 24.4 1.5 0.00029 20.6 2.5 1.8 2 0 0 2 2 2 1 Peptidase family M54 Peptidase_M10 PF00413.19 KFM12386.1 - 0.098 12.3 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Matrixin G-alpha PF00503.15 KFM12387.1 - 2.9e-87 292.8 2.5 3.2e-87 292.7 1.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KFM12387.1 - 9.4e-11 41.2 1.0 6.3e-10 38.5 0.3 2.2 1 1 0 2 2 2 1 ADP-ribosylation factor family CARD PF00619.16 KFM12388.1 - 6.8e-21 73.8 0.0 2.2e-20 72.2 0.0 2.0 1 0 0 1 1 1 1 Caspase recruitment domain PDZ PF00595.19 KFM12388.1 - 1.3e-06 28.4 0.0 3.1e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Guanylate_kin PF00625.16 KFM12388.1 - 8.2e-05 22.1 7.3 0.00013 21.5 0.0 2.7 2 0 0 2 2 2 1 Guanylate kinase fn3 PF00041.16 KFM12390.1 - 2e-165 537.3 44.1 2.4e-15 56.3 0.2 13.9 13 1 0 13 13 13 13 Fibronectin type III domain I-set PF07679.11 KFM12390.1 - 2.5e-68 225.9 0.0 3.7e-16 58.7 0.0 7.2 6 0 0 6 6 6 6 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM12390.1 - 7.4e-56 186.2 1.0 6e-11 42.3 0.0 7.3 7 0 0 7 7 7 6 Immunoglobulin domain Ig_3 PF13927.1 KFM12390.1 - 5.5e-36 122.8 4.0 5.4e-06 26.8 0.0 8.6 7 0 0 7 7 7 5 Immunoglobulin domain ig PF00047.20 KFM12390.1 - 1.9e-28 98.3 5.1 1.8e-07 31.1 0.0 7.7 8 0 0 8 8 8 5 Immunoglobulin domain V-set PF07686.12 KFM12390.1 - 6.2e-25 87.3 1.6 0.00036 20.4 0.0 8.2 8 1 0 8 8 8 5 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM12390.1 - 7.2e-09 35.4 0.7 0.074 12.9 0.0 5.7 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain Tissue_fac PF01108.12 KFM12390.1 - 8.1e-07 28.7 6.6 0.13 11.9 0.0 7.8 8 0 0 8 8 8 1 Tissue factor C1-set PF07654.10 KFM12390.1 - 3.4e-05 23.7 0.1 5 7.2 0.0 5.3 5 0 0 5 5 5 1 Immunoglobulin C1-set domain Yae1_N PF09811.4 KFM12391.1 - 8.1e-20 70.0 50.9 1.9e-07 30.5 6.3 5.0 1 1 2 3 3 3 3 Essential protein Yae1, N terminal p450 PF00067.17 KFM12392.1 - 8.9e-119 397.0 0.1 1e-118 396.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KFM12393.1 - 6.4e-117 390.9 0.1 7.3e-117 390.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fork_head PF00250.13 KFM12394.1 - 1.4e-41 140.4 0.3 2.1e-41 139.8 0.2 1.3 1 0 0 1 1 1 1 Fork head domain SPG48 PF14764.1 KFM12395.1 - 4.1e-188 625.5 14.0 4.1e-188 625.5 9.7 1.5 2 0 0 2 2 2 1 AP-5 complex subunit, vesicle trafficking DIL PF01843.14 KFM12396.1 - 1.6e-22 79.3 0.2 2.9e-22 78.5 0.2 1.4 1 0 0 1 1 1 1 DIL domain RA PF00788.18 KFM12396.1 - 1.1e-17 64.2 0.0 3.8e-17 62.5 0.0 1.9 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain PDZ PF00595.19 KFM12396.1 - 7.8e-11 41.9 0.0 1.4e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM12396.1 - 0.00025 20.8 0.0 0.00054 19.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain FHA PF00498.21 KFM12396.1 - 0.019 15.0 0.0 0.038 14.1 0.0 1.5 1 0 0 1 1 1 0 FHA domain HlyIII PF03006.15 KFM12397.1 - 4.9e-46 156.9 18.3 5.6e-46 156.7 12.7 1.0 1 0 0 1 1 1 1 Haemolysin-III related DUF4231 PF14015.1 KFM12397.1 - 7.2 6.6 6.6 13 5.8 0.2 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF4231) WD40 PF00400.27 KFM12398.1 - 5.7e-07 29.1 0.2 0.1 12.5 0.0 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat Nucleoside_tran PF01733.13 KFM12399.1 - 7.3e-51 173.1 2.3 2.9e-50 171.1 1.6 1.9 1 1 0 1 1 1 1 Nucleoside transporter F-box-like PF12937.2 KFM12400.1 - 2.4e-07 30.3 1.2 2.4e-07 30.3 0.9 2.7 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KFM12400.1 - 5.8e-07 29.0 1.6 5.8e-07 29.0 1.1 2.6 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.2 KFM12400.1 - 0.0019 17.7 15.6 0.041 13.5 0.2 5.9 4 2 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM12400.1 - 0.032 13.9 0.6 0.032 13.9 0.4 6.6 5 2 2 7 7 7 0 Leucine rich repeat LRR_6 PF13516.1 KFM12400.1 - 0.82 9.9 28.7 0.48 10.6 0.3 7.5 8 1 0 8 8 8 0 Leucine Rich repeat LRR_7 PF13504.1 KFM12400.1 - 1.2 9.6 21.5 3.7 8.1 0.5 7.6 8 1 0 8 8 8 0 Leucine rich repeat Actin PF00022.14 KFM12401.1 - 4.2e-162 539.0 0.0 4.7e-162 538.8 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 KFM12401.1 - 0.074 13.4 0.0 0.18 12.2 0.0 1.7 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Fascin PF06268.8 KFM12403.1 - 9.8e-102 334.7 0.4 3.3e-29 101.2 0.4 4.0 4 0 0 4 4 4 4 Fascin domain FRG1 PF06229.7 KFM12403.1 - 1.9e-14 53.5 3.6 0.034 13.6 0.0 6.6 3 3 4 7 7 7 5 FRG1-like family FGF PF00167.13 KFM12403.1 - 0.012 15.3 0.0 8.2 6.2 0.0 3.2 4 0 0 4 4 4 0 Fibroblast growth factor DUF4430 PF14478.1 KFM12403.1 - 0.44 10.6 2.8 3.1 7.9 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4430) DUF226 PF02890.9 KFM12404.1 - 0.068 12.9 0.7 0.13 12.0 0.5 1.3 1 0 0 1 1 1 0 Borrelia family of unknown function DUF226 Arm PF00514.18 KFM12405.1 - 2.4e-76 249.2 16.6 9.9e-12 44.2 0.1 8.8 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFM12405.1 - 1.5e-18 66.8 1.2 3.4e-05 24.0 0.0 6.0 1 1 7 8 8 8 6 HEAT repeats IBB PF01749.15 KFM12405.1 - 2.2e-18 66.1 6.3 3.4e-18 65.5 4.4 1.3 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 KFM12405.1 - 8.3e-17 61.1 7.7 9e-06 26.0 0.1 6.4 6 1 2 8 8 8 4 HEAT-like repeat HEAT PF02985.17 KFM12405.1 - 2.8e-09 36.2 2.1 0.28 11.3 0.0 7.1 7 0 0 7 7 7 2 HEAT repeat V-ATPase_H_C PF11698.3 KFM12405.1 - 0.00068 19.5 2.1 1.8 8.5 0.0 3.9 4 1 1 5 5 5 2 V-ATPase subunit H WD40 PF00400.27 KFM12406.1 - 9.3e-19 66.5 22.1 3.7e-07 29.7 0.3 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat Rax2 PF12768.2 KFM12406.1 - 2.9e-05 23.4 0.2 0.0017 17.6 0.0 2.6 3 0 0 3 3 3 2 Cortical protein marker for cell polarity WD40 PF00400.27 KFM12407.1 - 1.6e-21 75.3 21.3 1.4e-08 34.3 0.1 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.6 KFM12407.1 - 5.4e-05 22.9 0.7 0.18 11.5 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Rax2 PF12768.2 KFM12407.1 - 0.00018 20.7 0.7 0.018 14.2 0.1 2.4 2 0 0 2 2 2 2 Cortical protein marker for cell polarity Apc4_WD40 PF12894.2 KFM12407.1 - 0.017 14.5 0.2 3.7 7.1 0.0 3.5 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PP28 PF10252.4 KFM12408.1 - 3.6e-32 110.2 17.5 3.6e-32 110.2 12.1 2.4 2 1 0 2 2 2 1 Casein kinase substrate phosphoprotein PP28 G10 PF01125.12 KFM12409.1 - 8.6e-66 219.9 5.1 9.5e-66 219.8 3.5 1.0 1 0 0 1 1 1 1 G10 protein Metallothio_11 PF02066.10 KFM12409.1 - 2.5 8.0 9.6 0.33 10.8 3.8 1.6 1 1 1 2 2 2 0 Metallothionein family 11 PPR_2 PF13041.1 KFM12410.1 - 2.7e-49 164.9 0.9 1.4e-14 53.8 0.0 9.1 6 3 2 9 9 9 8 PPR repeat family PPR_3 PF13812.1 KFM12410.1 - 1.1e-20 72.0 0.0 0.0038 17.3 0.0 8.7 8 0 0 8 8 8 4 Pentatricopeptide repeat domain PPR PF01535.15 KFM12410.1 - 1.5e-19 68.5 13.5 7.4e-07 28.7 0.1 9.4 10 0 0 10 10 10 3 PPR repeat PPR_1 PF12854.2 KFM12410.1 - 6.5e-10 38.3 10.6 0.0011 18.3 0.0 8.6 10 0 0 10 10 10 2 PPR repeat MNE1 PF13762.1 KFM12410.1 - 0.049 13.7 2.1 18 5.3 0.1 4.0 2 2 2 4 4 4 0 Mitochondrial splicing apparatus component WRW PF10206.4 KFM12411.1 - 1.1e-23 83.2 0.0 1.2e-23 83.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f IRK PF01007.15 KFM12412.1 - 4.7e-171 568.1 0.1 5.6e-171 567.8 0.1 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel IRK_N PF08466.5 KFM12412.1 - 1.7e-26 91.8 0.3 3.2e-26 90.9 0.2 1.5 1 0 0 1 1 1 1 Inward rectifier potassium channel N-terminal Ion_trans_2 PF07885.11 KFM12412.1 - 0.039 13.6 7.2 0.12 12.1 5.0 1.8 1 1 0 1 1 1 0 Ion channel Pkinase PF00069.20 KFM12414.1 - 2.4e-54 184.1 0.0 2.9e-54 183.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM12414.1 - 5e-39 133.9 0.1 6.2e-39 133.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM12414.1 - 1.6e-08 33.8 0.0 3.4e-08 32.8 0.0 1.6 1 1 1 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 KFM12414.1 - 0.0029 16.5 0.2 0.0044 15.8 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 KFM12414.1 - 0.011 15.4 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFM12414.1 - 0.039 13.5 0.0 0.061 12.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 KFM12414.1 - 0.073 12.4 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Acetyltransf_CG PF14542.1 KFM12415.1 - 9.2e-22 76.7 0.2 1.1e-21 76.4 0.1 1.0 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_1 PF00583.19 KFM12415.1 - 0.0016 18.4 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 KFM12415.1 - 0.048 13.8 0.0 0.05 13.7 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3222 PF11519.3 KFM12415.1 - 0.14 12.0 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3222) Mito_morph_reg PF14972.1 KFM12416.1 - 5.4e-80 266.6 0.4 6.9e-80 266.2 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial morphogenesis regulator adh_short PF00106.20 KFM12417.1 - 2.1e-30 105.8 0.1 3.6e-30 105.0 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFM12417.1 - 3e-15 56.6 0.3 4.1e-15 56.2 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFM12417.1 - 3.3e-13 49.6 0.1 5.8e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KFM12417.1 - 1e-05 25.6 0.3 4.5e-05 23.5 0.2 2.1 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 KFM12417.1 - 1e-05 24.8 0.0 0.00026 20.2 0.0 2.2 1 1 1 2 2 2 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.10 KFM12417.1 - 0.00067 18.6 0.1 0.0012 17.8 0.1 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KFM12417.1 - 0.0084 15.5 0.3 0.028 13.8 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 KFM12417.1 - 0.019 15.0 0.1 0.073 13.1 0.1 2.0 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UCH PF00443.24 KFM12418.1 - 3.8e-64 216.3 0.2 5e-64 216.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFM12418.1 - 5.1e-29 101.6 0.1 7.7e-29 101.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KFM12418.1 - 4.2e-14 52.4 10.7 4.2e-14 52.4 7.4 2.4 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Peptidase_C98 PF15499.1 KFM12418.1 - 0.14 11.4 11.4 0.14 11.4 0.2 3.4 4 0 0 4 4 4 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase TACI-CRD2 PF09305.5 KFM12419.1 - 5e-14 51.8 18.1 7.9e-14 51.1 3.7 3.7 3 1 1 4 4 4 2 TACI, cysteine-rich domain BCMA-Tall_bind PF09257.5 KFM12419.1 - 0.018 14.9 15.9 0.032 14.1 4.2 3.3 3 0 0 3 3 3 0 BCMA, TALL-1 binding PH PF00169.24 KFM12420.1 - 4.6e-19 68.5 0.4 1.1e-16 60.8 0.2 2.9 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 KFM12420.1 - 2.6e-05 24.4 11.3 0.0004 20.6 1.3 4.7 4 2 0 4 4 4 2 Pleckstrin homology domain PLDc_2 PF13091.1 KFM12421.1 - 1e-24 86.6 0.0 1.2e-24 86.4 0.0 1.1 1 0 0 1 1 1 1 PLD-like domain DUF1669 PF07894.7 KFM12421.1 - 3.7e-05 23.0 0.1 7.5e-05 22.0 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1669) PLDc PF00614.17 KFM12421.1 - 0.033 14.0 0.4 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 Phospholipase D Active site motif Glyco_trans_4_4 PF13579.1 KFM12421.1 - 0.037 14.1 0.1 0.038 14.1 0.1 1.2 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Folliculin PF11704.3 KFM12422.1 - 8.4e-56 188.1 0.0 1.4e-55 187.4 0.0 1.3 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport PCI PF01399.22 KFM12423.1 - 5e-19 68.5 1.5 1e-18 67.5 0.1 2.2 2 0 0 2 2 2 1 PCI domain YjfB_motility PF14070.1 KFM12423.1 - 0.0032 17.2 0.1 0.013 15.2 0.1 2.0 1 0 0 1 1 1 1 Putative motility protein TPR_8 PF13181.1 KFM12423.1 - 0.0046 16.6 1.9 0.047 13.4 0.2 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFM12423.1 - 0.0068 15.9 2.5 0.015 14.8 0.6 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFM12423.1 - 0.016 15.1 0.9 0.28 11.1 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 KFM12423.1 - 0.069 13.1 2.3 0.15 12.0 0.6 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 KFM12423.1 - 0.46 10.1 2.7 1.6 8.4 0.3 2.6 3 0 0 3 3 3 0 TPR repeat NT5C PF06941.7 KFM12424.1 - 2.9e-79 265.0 0.0 3.3e-79 264.8 0.0 1.0 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Med9 PF07544.8 KFM12425.1 - 7.8e-20 70.4 2.4 8.5e-20 70.2 1.7 1.0 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Med21 PF11221.3 KFM12425.1 - 3.2e-07 30.4 2.2 3.7e-07 30.2 1.5 1.2 1 0 0 1 1 1 1 Subunit 21 of Mediator complex PHA_synth_III_E PF09712.5 KFM12425.1 - 0.0072 15.7 1.1 0.0081 15.6 0.8 1.1 1 0 0 1 1 1 1 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) ELK PF03789.8 KFM12425.1 - 0.019 14.7 1.8 0.15 11.8 0.3 2.3 2 0 0 2 2 2 0 ELK domain HAP1_N PF04849.8 KFM12425.1 - 0.02 13.8 3.0 0.028 13.3 2.1 1.3 1 1 0 1 1 1 0 HAP1 N-terminal conserved region DUF3452 PF11934.3 KFM12425.1 - 0.037 13.3 0.1 0.043 13.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) 4HB_MCP_1 PF12729.2 KFM12425.1 - 0.038 13.3 0.2 0.041 13.2 0.1 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction DASH_Duo1 PF08651.5 KFM12425.1 - 0.051 13.1 0.2 0.071 12.6 0.2 1.2 1 0 0 1 1 1 0 DASH complex subunit Duo1 DUF342 PF03961.8 KFM12425.1 - 0.057 11.8 2.3 0.064 11.6 1.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CHASE3 PF05227.8 KFM12425.1 - 0.06 13.0 1.0 0.075 12.7 0.7 1.1 1 0 0 1 1 1 0 CHASE3 domain TBPIP PF07106.8 KFM12425.1 - 0.063 12.8 2.2 0.075 12.5 1.6 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Phage_GP20 PF06810.6 KFM12425.1 - 0.064 12.6 1.6 0.077 12.4 1.1 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 MinC_N PF05209.8 KFM12425.1 - 0.069 12.9 0.4 0.08 12.7 0.3 1.1 1 0 0 1 1 1 0 Septum formation inhibitor MinC, N-terminal domain Syntaxin_2 PF14523.1 KFM12425.1 - 0.071 13.1 2.8 0.1 12.6 1.9 1.3 1 0 0 1 1 1 0 Syntaxin-like protein DUF745 PF05335.8 KFM12425.1 - 0.074 12.5 0.3 0.083 12.4 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Med2 PF11214.3 KFM12425.1 - 0.095 12.7 1.1 0.13 12.2 0.7 1.3 1 0 0 1 1 1 0 Mediator complex subunit 2 DUF964 PF06133.6 KFM12425.1 - 0.14 12.1 2.5 0.19 11.7 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF964) DUF2232 PF09991.4 KFM12425.1 - 0.15 11.0 0.8 0.17 10.8 0.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) BSD PF03909.12 KFM12425.1 - 0.2 11.4 1.0 0.75 9.5 0.2 1.9 2 0 0 2 2 2 0 BSD domain Med30 PF11315.3 KFM12425.1 - 0.21 11.7 4.1 0.44 10.6 2.9 1.5 1 1 0 1 1 1 0 Mediator complex subunit 30 Fib_alpha PF08702.5 KFM12425.1 - 0.26 11.3 4.8 0.45 10.6 3.3 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Enkurin PF13864.1 KFM12425.1 - 0.28 11.4 5.6 5.7 7.2 0.0 2.0 1 1 1 2 2 2 0 Calmodulin-binding IncA PF04156.9 KFM12425.1 - 0.3 10.6 2.9 0.39 10.2 2.0 1.2 1 0 0 1 1 1 0 IncA protein Ras PF00071.17 KFM12426.1 - 3.6e-37 127.2 0.0 4.7e-37 126.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM12426.1 - 4.9e-16 59.2 0.1 1.4e-15 57.8 0.0 1.8 2 1 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFM12426.1 - 3.4e-07 29.6 0.0 6.5e-07 28.7 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFM12426.1 - 7.8e-06 25.4 0.0 4.2e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KFM12426.1 - 0.007 15.5 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 KFM12426.1 - 0.011 15.4 0.1 0.056 13.1 0.0 1.9 1 1 0 1 1 1 0 Archaeal ATPase MMR_HSR1 PF01926.18 KFM12426.1 - 0.021 14.7 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Adenyl_transf PF04439.7 KFM12426.1 - 0.095 11.6 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Streptomycin adenylyltransferase AAA_22 PF13401.1 KFM12426.1 - 0.11 12.6 0.0 4.9 7.3 0.0 2.8 2 1 1 3 3 3 0 AAA domain PEMT PF04191.8 KFM12427.1 - 4.4e-21 74.9 4.8 4.4e-21 74.9 3.3 2.1 3 0 0 3 3 3 1 Phospholipid methyltransferase Herpes_UL74 PF07982.7 KFM12427.1 - 0.078 11.6 0.1 0.098 11.3 0.1 1.1 1 0 0 1 1 1 0 Herpes UL74 glycoproteins DUF95 PF01944.12 KFM12427.1 - 3.5 7.2 8.4 1.2 8.7 2.7 2.0 2 0 0 2 2 2 0 Integral membrane protein DUF95 VHS PF00790.14 KFM12429.1 - 6.1e-45 152.3 0.2 1.8e-44 150.7 0.0 1.8 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 KFM12429.1 - 4.1e-35 119.7 1.8 4.2e-34 116.5 2.0 2.0 2 0 0 2 2 2 1 GAT domain ENTH PF01417.15 KFM12429.1 - 0.0069 16.2 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 ENTH domain HEAT_2 PF13646.1 KFM12429.1 - 0.12 12.7 0.3 25 5.2 0.1 2.8 3 0 0 3 3 3 0 HEAT repeats FYVE_2 PF02318.11 KFM12429.1 - 0.17 11.7 1.0 12 5.8 0.0 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger ATP12 PF07542.6 KFM12430.1 - 7.3e-42 142.1 0.6 1.1e-41 141.6 0.4 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein Vac_ImportDeg PF09783.4 KFM12431.1 - 8.3e-58 194.7 5.2 9.3e-58 194.6 3.6 1.0 1 0 0 1 1 1 1 Vacuolar import and degradation protein Amidase_6 PF12671.2 KFM12431.1 - 0.048 13.7 1.2 0.067 13.2 0.4 1.3 1 1 0 1 1 1 0 Putative amidase domain TGS PF02824.16 KFM12432.1 - 1.8e-23 82.1 0.0 3.1e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 KFM12432.1 - 1.1e-17 64.1 0.0 1.7e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFM12432.1 - 2.6e-10 39.8 0.0 4.2e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 KFM12432.1 - 0.0023 18.4 0.0 0.0067 16.9 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 KFM12432.1 - 0.0073 16.1 0.3 0.76 9.5 0.0 2.3 1 1 1 2 2 2 1 Dynamin family ArgK PF03308.11 KFM12432.1 - 0.11 11.2 0.8 0.5 9.0 0.0 2.2 1 1 1 2 2 2 0 ArgK protein GTP_EFTU PF00009.22 KFM12432.1 - 0.14 11.5 0.5 7.3 5.9 0.2 2.9 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain 2OG-FeII_Oxy_2 PF13532.1 KFM12433.1 - 2.2e-10 40.6 0.0 4e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KFM12433.1 - 7.7e-05 22.9 0.0 0.00015 21.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ApoO PF09769.4 KFM12433.1 - 0.14 11.8 0.1 0.24 11.1 0.1 1.3 1 0 0 1 1 1 0 Apolipoprotein O Lgl_C PF08596.5 KFM12434.1 - 0.00013 20.5 0.0 0.0003 19.3 0.0 1.6 1 1 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal Gelsolin PF00626.17 KFM12435.1 - 1.5e-60 200.8 4.8 4.8e-15 55.0 0.0 6.9 6 0 0 6 6 6 6 Gelsolin repeat LRR_4 PF12799.2 KFM12435.1 - 4.6e-36 121.8 61.1 1.6e-08 33.9 4.0 9.2 2 2 8 12 12 12 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM12435.1 - 5.9e-36 122.0 49.0 1.8e-09 37.2 5.9 6.7 2 2 4 7 7 7 7 Leucine rich repeat LRR_1 PF00560.28 KFM12435.1 - 3.4e-18 62.8 55.4 0.0093 15.8 0.2 14.3 14 0 0 14 14 14 6 Leucine Rich Repeat LRR_7 PF13504.1 KFM12435.1 - 2.8e-08 32.6 55.5 0.14 12.4 0.5 12.5 12 0 0 12 12 12 6 Leucine rich repeat LRR_6 PF13516.1 KFM12435.1 - 0.0002 21.0 48.0 0.1 12.7 0.1 11.6 11 1 1 12 12 12 3 Leucine Rich repeat LRR_5 PF13306.1 KFM12435.1 - 0.13 12.0 3.0 2.5 7.8 0.2 3.0 2 1 0 3 3 3 0 Leucine rich repeats (6 copies) LRR_9 PF14580.1 KFM12435.1 - 0.21 11.1 13.1 1.2 8.6 0.0 3.8 1 1 1 3 3 3 0 Leucine-rich repeat Topoisom_bac PF01131.15 KFM12436.1 - 6.2e-104 348.0 0.0 9.5e-104 347.4 0.0 1.3 1 0 0 1 1 1 1 DNA topoisomerase zf-GRF PF06839.7 KFM12436.1 - 5.2e-35 119.1 22.2 3.3e-19 68.5 4.1 3.5 3 0 0 3 3 3 2 GRF zinc finger Toprim PF01751.17 KFM12436.1 - 1.9e-17 63.0 0.0 7.2e-17 61.2 0.0 2.0 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.14 KFM12436.1 - 1.4e-12 46.8 2.0 1.4e-12 46.8 1.4 3.6 4 0 0 4 4 4 1 Topoisomerase DNA binding C4 zinc finger zf-CCHC PF00098.18 KFM12436.1 - 4.4 7.4 10.3 0.07 13.0 1.6 2.4 2 0 0 2 2 2 0 Zinc knuckle Folliculin PF11704.3 KFM12437.1 - 1.3e-07 31.3 0.1 2.3e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport SHMT PF00464.14 KFM12438.1 - 2.5e-207 688.0 0.0 2.9e-207 687.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.12 KFM12438.1 - 0.0071 15.4 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family 7tm_1 PF00001.16 KFM12439.1 - 8.6e-52 175.8 19.8 1.2e-51 175.3 13.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) FA_desaturase PF00487.19 KFM12439.1 - 0.046 13.1 0.3 0.046 13.1 0.2 2.5 2 1 0 2 2 2 0 Fatty acid desaturase Pribosyl_synth PF14572.1 KFM12440.1 - 2.4e-101 337.1 1.4 3.6e-101 336.4 1.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 KFM12440.1 - 2.3e-38 130.5 1.6 3.4e-38 129.9 0.4 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 KFM12440.1 - 0.00041 20.0 3.2 0.0036 17.0 1.2 2.7 2 1 0 2 2 2 1 Phosphoribosyl transferase domain UN_NPL4 PF11543.3 KFM12440.1 - 0.019 15.2 0.0 0.037 14.2 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 RelB PF04221.7 KFM12440.1 - 0.026 14.2 0.1 3.8 7.3 0.0 2.6 2 0 0 2 2 2 0 RelB antitoxin SSF PF00474.12 KFM12441.1 - 1.3e-123 412.6 15.8 1.7e-123 412.2 10.9 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family DUF3814 PF12769.2 KFM12441.1 - 1.1 9.4 9.1 0.29 11.3 0.9 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3814) SH2 PF00017.19 KFM12442.1 - 1.5e-23 82.3 0.4 2.2e-23 81.8 0.3 1.2 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.23 KFM12442.1 - 3.4e-22 77.5 0.1 1.3e-12 46.8 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 KFM12442.1 - 1.5e-20 72.5 0.1 2.3e-12 46.2 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 KFM12442.1 - 4.3e-17 61.3 0.0 2.8e-12 45.9 0.0 2.6 3 0 0 3 3 3 2 Variant SH3 domain ENTH PF01417.15 KFM12443.1 - 7e-55 184.2 0.2 1.6e-54 183.0 0.2 1.7 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 KFM12443.1 - 1e-06 27.6 0.1 1.5e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.14 KFM12443.1 - 6.4e-05 22.6 0.9 0.00012 21.7 0.2 1.7 2 0 0 2 2 2 1 VHS domain UIM PF02809.15 KFM12443.1 - 0.00084 18.7 2.0 0.00084 18.7 1.4 2.4 2 0 0 2 2 2 1 Ubiquitin interaction motif B9-C2 PF07162.6 KFM12444.1 - 1.5e-46 158.2 0.2 1.8e-46 158.0 0.1 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Ion_trans PF00520.26 KFM12445.1 - 4.6e-208 685.4 85.9 2.8e-62 209.5 11.3 4.3 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.7 KFM12445.1 - 1.5e-13 49.9 80.0 9.8e-08 30.8 1.5 9.6 5 4 3 9 9 9 6 Polycystin cation channel EphA2_TM PF14575.1 KFM12445.1 - 0.00017 21.9 0.7 22 5.4 0.1 5.3 4 0 0 4 4 4 2 Ephrin type-A receptor 2 transmembrane domain C1q PF00386.16 KFM12446.1 - 1.4e-33 115.5 1.7 1.8e-33 115.2 1.2 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 KFM12446.1 - 3.9e-08 32.7 14.1 5.7e-08 32.1 9.7 1.1 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) 7tm_1 PF00001.16 KFM12447.1 - 6.8e-69 231.8 25.9 7.9e-69 231.6 18.0 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM12447.1 - 3.7e-15 55.7 22.3 4.3e-15 55.5 15.5 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 KFM12447.1 - 2.9e-08 33.1 19.4 4.1e-08 32.7 13.4 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.4 KFM12447.1 - 1.6e-06 27.4 21.6 2.7e-06 26.7 14.9 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Serpentine_r_xa PF03383.10 KFM12447.1 - 0.0038 17.0 4.1 0.0038 17.0 2.9 2.5 1 1 0 2 2 2 1 Caenorhabditis serpentine receptor-like protein, class xa Herpes_US9 PF06072.6 KFM12447.1 - 0.034 13.9 1.7 0.034 13.9 1.2 3.0 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 zf-LITAF-like PF10601.4 KFM12447.1 - 1.7 8.5 0.0 1.7 8.5 0.0 3.8 3 1 1 4 4 4 0 LITAF-like zinc ribbon domain LMF1 PF06762.9 KFM12448.1 - 1.6e-145 484.7 1.2 1.9e-145 484.4 0.9 1.1 1 0 0 1 1 1 1 Lipase maturation factor DUF2797 PF10977.3 KFM12449.1 - 0.98 8.9 7.9 2.1 7.9 5.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) G-gamma PF00631.17 KFM12450.1 - 3.7e-12 45.7 0.2 4e-12 45.6 0.2 1.0 1 0 0 1 1 1 1 GGL domain Delta_lysin PF05372.6 KFM12450.1 - 0.035 13.4 0.2 0.053 12.8 0.2 1.2 1 0 0 1 1 1 0 Delta lysin family DUF310 PF03750.8 KFM12450.1 - 0.13 12.4 0.0 0.15 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF310) AAA PF00004.24 KFM12452.1 - 1.3e-13 51.3 0.0 2e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFM12452.1 - 1.1e-10 41.3 0.0 2.3e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KFM12452.1 - 2.8e-08 33.0 0.0 4e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KFM12452.1 - 1.8e-06 27.8 0.0 2.9e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 KFM12452.1 - 1.8e-06 26.9 0.1 3.7e-06 25.9 0.0 1.4 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KFM12452.1 - 8.1e-06 26.0 0.0 0.00017 21.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFM12452.1 - 1.5e-05 25.7 0.4 6.1e-05 23.8 0.0 2.2 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.1 KFM12452.1 - 7.6e-05 23.0 0.0 0.00017 21.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFM12452.1 - 0.00019 21.1 0.0 0.0004 20.0 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 KFM12452.1 - 0.00028 20.7 0.0 0.00065 19.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFM12452.1 - 0.00046 20.2 0.0 0.079 12.9 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain TIP49 PF06068.8 KFM12452.1 - 0.0021 16.8 0.0 0.003 16.3 0.0 1.1 1 0 0 1 1 1 1 TIP49 C-terminus AAA_3 PF07726.6 KFM12452.1 - 0.003 17.1 0.0 0.006 16.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KFM12452.1 - 0.0034 16.4 0.0 0.0051 15.9 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin Sigma54_activ_2 PF14532.1 KFM12452.1 - 0.0035 17.3 0.0 0.008 16.2 0.0 1.6 1 1 0 1 1 1 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 KFM12452.1 - 0.004 16.5 0.1 0.013 14.9 0.0 1.6 1 1 0 1 1 1 1 IstB-like ATP binding protein Viral_helicase1 PF01443.13 KFM12452.1 - 0.0042 16.6 0.1 0.06 12.8 0.0 2.0 1 1 1 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 KFM12452.1 - 0.0043 16.4 0.2 0.021 14.2 0.1 1.8 1 1 1 2 2 2 1 AAA domain NTPase_1 PF03266.10 KFM12452.1 - 0.006 16.2 0.3 0.14 11.8 0.0 2.3 1 1 1 2 2 2 1 NTPase NACHT PF05729.7 KFM12452.1 - 0.007 16.0 0.0 0.15 11.7 0.0 2.2 1 1 1 2 2 2 1 NACHT domain AAA_28 PF13521.1 KFM12452.1 - 0.0082 16.1 0.8 0.061 13.2 0.0 2.3 1 1 1 2 2 2 1 AAA domain ABC_tran PF00005.22 KFM12452.1 - 0.014 15.7 0.0 0.033 14.4 0.0 1.6 1 1 1 2 2 1 0 ABC transporter RNA_helicase PF00910.17 KFM12452.1 - 0.02 15.0 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 KFM12452.1 - 0.021 13.6 0.0 0.034 13.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF258 PF03193.11 KFM12452.1 - 0.022 13.9 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 KFM12452.1 - 0.042 13.4 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain NAD_binding_1 PF00175.16 KFM12452.1 - 0.043 14.3 0.0 0.84 10.2 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain AAA_2 PF07724.9 KFM12452.1 - 0.065 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Bac_DnaA PF00308.13 KFM12452.1 - 0.098 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial dnaA protein Arch_ATPase PF01637.13 KFM12452.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase PseudoU_synth_2 PF00849.17 KFM12453.1 - 4.4e-25 88.4 0.0 6.3e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Corona_S1 PF01600.11 KFM12453.1 - 0.027 12.8 0.1 0.036 12.3 0.0 1.1 1 0 0 1 1 1 0 Coronavirus S1 glycoprotein Mesothelin PF06060.7 KFM12454.1 - 2.6e-08 32.4 0.1 2.9e-08 32.2 0.1 1.0 1 0 0 1 1 1 1 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) Mesothelin PF06060.7 KFM12456.1 - 2.5e-127 425.5 0.1 2.9e-127 425.3 0.1 1.0 1 0 0 1 1 1 1 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) Flavodoxin_NdrI PF07972.6 KFM12456.1 - 0.019 14.8 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 NrdI Flavodoxin like Fe_hyd_lg_C PF02906.9 KFM12458.1 - 1.3e-89 300.2 0.0 1.9e-89 299.7 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.12 KFM12458.1 - 2.1e-09 37.2 0.2 4.1e-09 36.2 0.1 1.5 1 0 0 1 1 1 1 Iron hydrogenase small subunit Lactamase_B PF00753.22 KFM12459.1 - 5.3e-21 75.1 0.3 7.7e-21 74.6 0.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KFM12459.1 - 5.9e-05 22.6 0.1 9e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KFM12460.1 - 4.6e-27 94.9 0.5 6e-27 94.5 0.3 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KFM12460.1 - 6.9e-05 22.4 0.0 0.0001 21.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Sulfotransfer_1 PF00685.22 KFM12462.1 - 1.1e-32 113.3 0.0 1.3e-32 113.0 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_2 PF03567.9 KFM12462.1 - 0.013 15.2 0.0 0.036 13.7 0.0 1.7 2 0 0 2 2 2 0 Sulfotransferase family SelR PF01641.13 KFM12463.1 - 1.9e-16 59.8 0.3 2.1e-16 59.7 0.2 1.0 1 0 0 1 1 1 1 SelR domain Zn_ribbon_recom PF13408.1 KFM12463.1 - 0.0024 18.0 0.4 1.3 9.3 0.0 2.2 2 0 0 2 2 2 2 Recombinase zinc beta ribbon domain Lar_restr_allev PF14354.1 KFM12463.1 - 0.0077 16.5 0.4 0.041 14.1 0.2 1.9 1 1 0 1 1 1 1 Restriction alleviation protein Lar zinc_ribbon_2 PF13240.1 KFM12463.1 - 0.022 14.2 1.4 1.7 8.1 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain RRN7 PF11781.3 KFM12463.1 - 0.034 13.6 1.0 0.98 8.9 0.2 2.2 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zinc_ribbon_4 PF13717.1 KFM12463.1 - 0.036 13.7 3.2 0.51 10.0 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain GFA PF04828.9 KFM12463.1 - 0.038 13.9 1.2 5.9 6.9 0.0 2.0 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme TFIIS_C PF01096.13 KFM12463.1 - 0.046 13.3 1.3 1.5 8.5 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zinc_ribbon_5 PF13719.1 KFM12463.1 - 0.055 13.0 3.8 0.62 9.7 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 KFM12463.1 - 0.091 12.5 0.7 0.2 11.5 0.5 1.6 1 1 0 1 1 1 0 Double zinc ribbon Yippee-Mis18 PF03226.9 KFM12463.1 - 0.11 12.5 0.2 0.18 11.8 0.1 1.4 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-ribbon_3 PF13248.1 KFM12463.1 - 0.14 11.4 2.7 3.4 7.0 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.8 KFM12463.1 - 0.15 11.5 3.1 1 8.8 0.1 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Zn_Tnp_IS1595 PF12760.2 KFM12463.1 - 0.17 11.7 1.2 2.7 7.8 0.1 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain PhnA_Zn_Ribbon PF08274.7 KFM12463.1 - 0.26 11.0 0.1 0.26 11.0 0.1 1.8 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Zn-ribbon_8 PF09723.5 KFM12463.1 - 0.3 11.0 1.4 2.9 7.9 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.7 KFM12463.1 - 0.53 9.6 4.5 5.6 6.3 0.1 2.8 2 1 1 3 3 3 0 TFIIB zinc-binding A2L_zn_ribbon PF08792.5 KFM12463.1 - 0.8 9.2 4.7 1.4 8.4 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-NADH-PPase PF09297.6 KFM12463.1 - 1.2 8.6 5.6 1.8 8.1 0.1 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DUF2404 PF10296.4 KFM12465.1 - 3.1e-30 104.1 1.6 1.6e-28 98.6 0.0 3.0 3 0 0 3 3 3 1 Putative integral membrane protein conserved region (DUF2404) Ribosomal_L3 PF00297.17 KFM12466.1 - 7.8e-116 386.0 12.1 9.6e-116 385.7 8.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 NDUFB10 PF10249.4 KFM12467.1 - 2.3e-52 176.4 8.3 2.6e-52 176.3 5.7 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 Orn_DAP_Arg_deC PF00278.17 KFM12467.1 - 0.14 11.8 0.0 0.8 9.4 0.0 1.9 2 0 0 2 2 2 0 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ribosomal_S5 PF00333.15 KFM12468.1 - 5.2e-29 99.7 0.5 8.8e-29 99.0 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 KFM12468.1 - 4.8e-22 77.0 0.0 9e-22 76.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain WD40 PF00400.27 KFM12469.1 - 4e-76 248.4 34.3 2.7e-10 39.7 0.2 12.0 13 0 0 13 13 13 11 WD domain, G-beta repeat Utp13 PF08625.6 KFM12469.1 - 2.6e-48 163.2 2.3 4.4e-48 162.5 1.6 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 KFM12469.1 - 1.8e-06 26.3 10.9 0.36 8.8 0.0 6.1 4 2 2 6 6 6 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KFM12469.1 - 0.0011 17.7 6.8 3.9 6.1 0.1 5.1 2 2 2 4 4 4 3 Nup133 N terminal like TrkA_C PF02080.16 KFM12469.1 - 0.17 11.4 0.2 7.7 6.1 0.0 2.6 2 0 0 2 2 2 0 TrkA-C domain SH3_9 PF14604.1 KFM12470.1 - 3.6e-17 61.6 0.0 5.4e-11 41.8 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KFM12470.1 - 5e-16 57.8 0.8 5e-10 38.5 0.0 2.3 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 KFM12470.1 - 1.4e-13 50.1 0.0 3e-09 36.2 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.6 KFM12470.1 - 1.3e-07 31.6 0.5 0.00075 19.6 0.0 2.4 2 0 0 2 2 2 2 Bacterial SH3 domain PX PF00787.19 KFM12470.1 - 2e-07 30.7 0.9 4.2e-07 29.7 0.4 1.7 2 0 0 2 2 2 1 PX domain p47_phox_C PF08944.6 KFM12470.1 - 2.7e-05 24.2 0.4 8.7e-05 22.6 0.3 1.9 1 0 0 1 1 1 1 NADPH oxidase subunit p47Phox, C terminal domain SH3_4 PF06347.8 KFM12470.1 - 0.00042 19.8 0.4 0.0018 17.7 0.0 2.0 2 0 0 2 2 2 1 Bacterial SH3 domain Evr1_Alr PF04777.8 KFM12471.1 - 1.5e-29 101.7 1.9 1.9e-29 101.4 1.3 1.0 1 0 0 1 1 1 1 Erv1 / Alr family MARVEL PF01284.18 KFM12472.1 - 2.6e-19 69.4 14.1 3.2e-19 69.1 9.8 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF1129 PF06570.6 KFM12472.1 - 0.046 13.0 0.5 0.065 12.5 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) DUF843 PF05814.6 KFM12472.1 - 0.36 10.6 3.4 12 5.8 0.0 3.2 2 1 1 3 3 3 0 Baculovirus protein of unknown function (DUF843) DUF3429 PF11911.3 KFM12472.1 - 0.46 10.4 6.9 0.14 12.1 2.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3429) DUF4131 PF13567.1 KFM12472.1 - 1.5 8.2 4.8 2.5 7.4 3.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) PEN-2 PF10251.4 KFM12472.1 - 2.9 8.1 6.5 1 9.6 2.3 1.8 1 1 1 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase DUF2165 PF09933.4 KFM12472.1 - 3.9 7.1 8.5 18 4.9 6.1 1.8 1 1 1 2 2 2 0 Predicted small integral membrane protein (DUF2165) zf-C2H2_4 PF13894.1 KFM12473.1 - 0.0093 16.2 0.7 0.0093 16.2 0.5 6.4 6 0 0 6 6 6 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KFM12473.1 - 0.015 15.5 0.6 0.015 15.5 0.4 5.6 6 0 0 6 6 6 0 Zinc finger, C2H2 type Prenyltrans_2 PF13249.1 KFM12473.1 - 0.089 13.2 0.1 0.41 11.0 0.0 2.2 1 0 0 1 1 1 0 Prenyltransferase-like EBP50_C-term PF09007.6 KFM12474.1 - 2.6e-23 81.5 1.3 4.5e-23 80.8 0.9 1.4 1 0 0 1 1 1 1 EBP50, C-terminal PDZ PF00595.19 KFM12474.1 - 7.9e-15 54.8 0.0 7.9e-14 51.5 0.0 2.2 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM12474.1 - 3.3e-06 26.9 0.0 9.5e-06 25.4 0.0 1.9 1 1 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.9 KFM12474.1 - 0.012 15.5 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain HhH-GPD PF00730.20 KFM12475.1 - 2.9e-19 69.3 0.0 4.2e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KFM12475.1 - 2.4e-09 36.3 0.0 4.4e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.4 KFM12475.1 - 0.037 14.2 3.9 0.068 13.3 2.7 1.5 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Tuberin PF03542.11 KFM12476.1 - 1.1e-135 452.3 8.8 2.6e-135 451.1 6.1 1.6 1 0 0 1 1 1 1 Tuberin DUF3384 PF11864.3 KFM12476.1 - 1.4e-114 383.1 11.0 1.3e-113 379.9 5.0 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 KFM12476.1 - 2.8e-45 154.0 0.0 4.8e-45 153.2 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP PKD PF00801.15 KFM12477.1 - 2.9e-148 481.8 100.1 4.5e-15 55.1 1.1 17.6 18 0 0 18 18 18 15 PKD domain REJ PF02010.10 KFM12477.1 - 1e-107 360.2 0.2 8e-107 357.2 0.0 2.6 3 0 0 3 3 3 1 REJ domain PKD_channel PF08016.7 KFM12477.1 - 3.4e-95 318.9 21.2 5e-95 318.4 14.7 1.3 1 0 0 1 1 1 1 Polycystin cation channel PLAT PF01477.18 KFM12477.1 - 2.1e-21 76.3 0.1 1e-20 74.2 0.1 2.2 1 0 0 1 1 1 1 PLAT/LH2 domain LRR_8 PF13855.1 KFM12477.1 - 1e-11 44.4 4.0 3.6e-11 42.6 2.8 2.0 1 0 0 1 1 1 1 Leucine rich repeat Lectin_C PF00059.16 KFM12477.1 - 1.5e-11 44.8 2.0 3e-11 43.8 0.3 2.5 2 0 0 2 2 2 1 Lectin C-type domain Y_Y_Y PF07495.8 KFM12477.1 - 1.9e-07 30.7 20.0 0.027 14.2 0.0 7.6 8 0 0 8 8 8 3 Y_Y_Y domain GPS PF01825.16 KFM12477.1 - 4e-07 30.0 0.0 1.5e-06 28.1 0.0 2.1 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain LRR_4 PF12799.2 KFM12477.1 - 5.3e-05 22.7 6.6 0.00019 20.9 1.0 2.9 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) WSC PF01822.14 KFM12477.1 - 6.8e-05 22.7 7.9 0.00015 21.5 5.5 1.7 1 0 0 1 1 1 1 WSC domain WD40 PF00400.27 KFM12478.1 - 1.2e-46 154.9 28.7 4.5e-11 42.1 1.0 8.3 9 0 0 9 9 9 7 WD domain, G-beta repeat zf-C3HC4_2 PF13923.1 KFM12478.1 - 3.3e-06 27.0 10.4 3.3e-06 27.0 7.2 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.11 KFM12478.1 - 5.6e-06 26.1 9.7 0.0012 18.5 0.5 2.5 1 1 1 2 2 2 2 Seven in absentia protein family zf-TRAF PF02176.13 KFM12478.1 - 1.1e-05 25.7 6.1 1.1e-05 25.7 4.2 2.8 3 1 0 3 3 2 1 TRAF-type zinc finger zf-C3HC4 PF00097.20 KFM12478.1 - 3.8e-05 23.2 10.3 3.8e-05 23.2 7.1 3.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFM12478.1 - 0.00012 21.9 7.5 0.00012 21.9 5.2 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 KFM12478.1 - 0.00018 21.1 11.8 0.00091 18.8 8.1 2.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Nup160 PF11715.3 KFM12478.1 - 0.00068 17.8 7.5 0.0015 16.7 0.1 3.4 3 2 1 4 4 4 1 Nucleoporin Nup120/160 zf-RING_5 PF14634.1 KFM12478.1 - 0.0022 17.6 13.5 0.0022 17.6 9.4 3.1 2 0 0 2 2 2 1 zinc-RING finger domain PQQ_3 PF13570.1 KFM12478.1 - 0.013 15.7 1.7 2.1 8.7 0.0 4.5 5 1 0 5 5 5 0 PQQ-like domain PQQ_2 PF13360.1 KFM12478.1 - 0.087 12.2 0.4 0.62 9.4 0.1 2.3 1 1 0 2 2 2 0 PQQ-like domain HSBP1 PF06825.7 KFM12478.1 - 0.1 12.1 1.6 0.22 11.1 1.1 1.4 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Utp11 PF03998.8 KFM12478.1 - 0.16 11.7 0.2 0.24 11.1 0.1 1.2 1 0 0 1 1 1 0 Utp11 protein Glyco_hydro_20 PF00728.17 KFM12479.1 - 4.5e-15 55.6 0.0 7e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain DUF1146 PF06612.6 KFM12479.1 - 0.13 12.1 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1146) WD40 PF00400.27 KFM12481.1 - 6.7e-29 98.7 6.9 1.2e-08 34.5 0.0 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 KFM12481.1 - 0.00022 19.5 0.7 0.052 11.6 0.2 2.9 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Hira PF07569.6 KFM12481.1 - 0.00024 20.3 0.2 0.096 11.8 0.0 2.5 2 1 1 3 3 3 2 TUP1-like enhancer of split IKI3 PF04762.7 KFM12481.1 - 0.0016 16.3 0.1 0.19 9.4 0.0 2.1 2 0 0 2 2 2 2 IKI3 family DUF2415 PF10313.4 KFM12481.1 - 0.051 13.2 0.1 3.5 7.3 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) BRICHOS PF04089.9 KFM12482.1 - 1.5e-13 50.3 0.0 2.5e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 BRICHOS domain LIF_OSM PF01291.12 KFM12482.1 - 0.048 13.5 0.4 0.071 13.0 0.3 1.2 1 0 0 1 1 1 0 LIF / OSM family Hydrolase_like PF13242.1 KFM12483.1 - 2e-18 65.8 0.0 3e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 KFM12483.1 - 2.7e-05 24.4 0.0 3.4e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFM12483.1 - 0.00025 21.5 0.0 0.00032 21.1 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 KFM12483.1 - 0.001 18.4 0.1 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase zf-C2H2 PF00096.21 KFM12484.1 - 1e-39 132.5 73.1 0.0001 22.4 1.0 10.4 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM12484.1 - 8.7e-38 126.7 78.9 5.6e-08 32.7 1.1 11.0 12 0 0 12 12 12 9 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM12484.1 - 5.9e-33 110.7 56.8 0.00067 19.8 0.1 10.6 10 0 0 10 10 10 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM12484.1 - 2.7e-23 81.4 36.4 2.9e-05 24.0 0.3 10.2 10 0 0 10 10 10 7 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFM12484.1 - 2.5e-12 46.2 58.5 1.5e-06 27.8 2.0 9.9 10 0 0 10 10 10 7 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KFM12484.1 - 1.3e-05 24.7 35.0 0.23 11.1 0.2 8.4 8 0 0 8 8 8 3 zinc-finger of a C2HC-type zf-met PF12874.2 KFM12484.1 - 0.00096 19.2 0.5 0.00096 19.2 0.4 8.5 9 0 0 9 9 9 3 Zinc-finger of C2H2 type Zn_Tnp_IS1595 PF12760.2 KFM12484.1 - 0.002 17.9 50.3 0.012 15.4 1.7 7.1 5 2 1 6 6 5 4 Transposase zinc-ribbon domain zf-C2H2_2 PF12756.2 KFM12484.1 - 0.0023 17.9 43.0 0.27 11.3 0.1 8.8 3 2 6 9 9 9 3 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.5 KFM12484.1 - 0.0057 16.5 50.5 1 9.3 2.5 9.7 8 2 1 9 9 9 3 Zinc ribbon domain zf-Di19 PF05605.7 KFM12484.1 - 0.04 14.0 38.9 0.32 11.1 0.2 7.1 4 2 1 7 7 7 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_3 PF14369.1 KFM12484.1 - 0.048 13.6 21.8 1.5 8.8 0.0 7.4 7 0 0 7 7 7 0 zinc-finger XPA_N PF01286.13 KFM12484.1 - 0.062 12.9 0.4 0.062 12.9 0.3 7.5 9 0 0 9 9 8 0 XPA protein N-terminal zf-piccolo PF05715.8 KFM12484.1 - 0.66 10.0 7.1 6.6 6.8 0.1 3.3 3 0 0 3 3 3 0 Piccolo Zn-finger C1_1 PF00130.17 KFM12484.1 - 10 5.9 35.1 0.75 9.5 0.1 7.3 3 2 6 9 9 9 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-DHHC PF01529.15 KFM12485.1 - 7.1e-35 119.9 12.6 7.1e-35 119.9 8.7 2.0 2 1 0 2 2 2 1 DHHC palmitoyltransferase FH2 PF02181.18 KFM12486.1 - 9.5e-89 297.8 9.6 1.3e-88 297.4 6.7 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain PDZ PF00595.19 KFM12486.1 - 9.3e-14 51.3 0.0 1.7e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM12486.1 - 0.0014 18.4 0.0 0.0034 17.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain SSF PF00474.12 KFM12487.1 - 5.2e-146 486.4 20.5 7.4e-146 485.9 14.2 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family BAR PF03114.13 KFM12489.1 - 7.5e-51 172.8 6.8 1.6e-50 171.7 4.7 1.6 1 0 0 1 1 1 1 BAR domain RhoGAP PF00620.22 KFM12489.1 - 8.3e-45 152.1 0.1 4.4e-44 149.7 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain BAR_2 PF10455.4 KFM12489.1 - 0.00081 18.3 1.4 0.0017 17.3 1.0 1.5 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking LCM PF04072.9 KFM12490.1 - 5e-35 120.7 0.0 7e-35 120.2 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase MIP PF00230.15 KFM12491.1 - 0.00017 21.0 0.0 0.0002 20.8 0.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein Pkinase PF00069.20 KFM12492.1 - 1.3e-62 211.2 0.0 1.9e-62 210.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM12492.1 - 8.8e-38 129.8 0.0 1.3e-37 129.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.25 KFM12492.1 - 1.3e-25 89.0 0.2 2.2e-25 88.3 0.1 1.4 1 0 0 1 1 1 1 C2 domain C1_1 PF00130.17 KFM12492.1 - 3.2e-18 65.2 17.2 9.7e-17 60.4 4.2 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 KFM12492.1 - 1.6e-06 28.5 1.4 3.2e-06 27.5 1.0 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KFM12492.1 - 0.0045 15.9 0.0 0.0093 14.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like CEP76-C2 PF15627.1 KFM12492.1 - 0.028 13.9 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 CEP76 C2 domain APH PF01636.18 KFM12492.1 - 0.11 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family C1_3 PF07649.7 KFM12492.1 - 3.2 7.8 17.0 1.1 9.3 3.6 2.9 2 0 0 2 2 2 0 C1-like domain Pkinase_C PF00433.19 KFM12493.1 - 1.5e-11 44.6 2.4 1.7e-11 44.4 1.7 1.0 1 0 0 1 1 1 1 Protein kinase C terminal domain PMP22_Claudin PF00822.15 KFM12494.1 - 3.7e-34 117.7 0.4 4.9e-34 117.3 0.3 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFM12494.1 - 4.7e-10 39.4 0.1 7.6e-10 38.7 0.1 1.4 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Tetraspannin PF00335.15 KFM12494.1 - 0.0041 16.4 0.0 0.0053 16.0 0.0 1.1 1 0 0 1 1 1 1 Tetraspanin family AtpR PF12966.2 KFM12494.1 - 0.15 12.2 1.0 0.38 10.9 0.1 2.0 2 0 0 2 2 2 0 N-ATPase, AtpR subunit U-box PF04564.10 KFM12495.1 - 2.6e-07 30.5 0.0 9.7e-07 28.6 0.0 2.0 1 0 0 1 1 1 1 U-box domain zf-C3HC4_2 PF13923.1 KFM12495.1 - 5.4e-07 29.5 11.9 5.4e-07 29.5 8.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DWNN PF08783.6 KFM12495.1 - 5.3e-06 26.2 0.1 1.9e-05 24.5 0.1 2.1 1 0 0 1 1 1 1 DWNN domain zf-CCHC PF00098.18 KFM12495.1 - 1.2e-05 24.9 3.1 1.2e-05 24.9 2.1 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.1 KFM12495.1 - 0.00013 21.3 5.8 0.00013 21.3 4.0 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-RING_2 PF13639.1 KFM12495.1 - 0.00015 21.5 11.8 0.00026 20.7 8.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KFM12495.1 - 0.0018 17.9 11.1 0.0018 17.9 7.7 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFM12495.1 - 0.0018 17.9 9.3 0.0018 17.9 6.5 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFM12495.1 - 0.0095 15.7 12.1 0.024 14.5 8.4 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KFM12495.1 - 0.014 15.0 12.2 0.028 14.0 8.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KFM12495.1 - 0.32 10.8 4.5 0.59 9.9 3.1 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Ago_hook PF10427.4 KFM12496.1 - 4.4e-26 91.6 18.9 4.4e-26 91.6 13.1 13.1 6 4 7 13 13 13 1 Argonaute hook RRM_5 PF13893.1 KFM12496.1 - 3.7e-06 26.6 0.0 7e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFM12496.1 - 0.002 17.7 0.0 0.0051 16.4 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM12496.1 - 0.0026 17.6 0.0 0.0076 16.2 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PP-binding PF00550.20 KFM12497.1 - 5.4e-11 42.5 0.1 5.9e-11 42.4 0.1 1.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 KFM12497.1 - 0.0013 18.6 0.2 0.0013 18.6 0.1 1.0 1 0 0 1 1 1 1 Acyl-carrier Ribosomal_L50 PF10501.4 KFM12497.1 - 0.11 12.4 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal subunit 39S Hexapep PF00132.19 KFM12499.1 - 7.8e-17 59.9 19.7 1.4e-06 27.5 0.5 4.4 3 1 2 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KFM12499.1 - 7.2e-06 25.4 13.4 0.00011 21.6 2.1 3.7 3 1 1 4 4 4 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 KFM12499.1 - 0.078 11.5 0.1 0.099 11.1 0.0 1.3 1 0 0 1 1 1 0 L-fucokinase EB PF01683.13 KFM12499.1 - 0.25 11.4 2.3 1.3 9.1 1.6 2.2 1 1 0 1 1 1 0 EB module Pkinase PF00069.20 KFM12500.1 - 2e-48 164.7 0.0 2.9e-48 164.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain POLO_box PF00659.13 KFM12500.1 - 1.2e-46 156.4 0.9 9e-23 80.0 0.0 2.4 2 0 0 2 2 2 2 POLO box duplicated region Pkinase_Tyr PF07714.12 KFM12500.1 - 2e-26 92.6 0.0 3.3e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM12500.1 - 2.5e-06 26.6 0.0 3.6e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFM12500.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 KFM12501.1 - 7.2e-41 140.0 0.0 1.1e-40 139.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 KFM12501.1 - 4.6e-36 123.5 0.0 8.5e-36 122.6 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 KFM12501.1 - 8.6e-23 80.7 0.0 1.3e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PQQ_2 PF13360.1 KFM12501.1 - 3.6e-09 36.4 0.0 0.00042 19.8 0.0 2.9 2 1 1 3 3 3 2 PQQ-like domain PQQ PF01011.16 KFM12501.1 - 2e-07 30.2 0.1 0.017 14.6 0.0 3.3 3 0 0 3 3 3 2 PQQ enzyme repeat PQQ_3 PF13570.1 KFM12501.1 - 0.013 15.7 1.2 25 5.2 0.0 5.3 6 0 0 6 6 6 0 PQQ-like domain APH PF01636.18 KFM12501.1 - 0.014 15.1 0.8 0.4 10.3 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KFM12501.1 - 0.024 13.6 0.0 0.044 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ubiquitin PF00240.18 KFM12502.1 - 1.8e-11 43.2 0.0 3.4e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 KFM12502.1 - 0.00033 20.8 0.0 0.0022 18.2 0.0 2.3 2 1 0 2 2 2 1 Ubiquitin-like domain DUF4249 PF14054.1 KFM12502.1 - 0.029 13.7 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4249) Epimerase_2 PF02350.14 KFM12502.1 - 0.072 11.8 0.0 0.095 11.4 0.0 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase tRNA-synt_1c PF00749.16 KFM12503.1 - 4.5e-86 288.3 0.0 6.7e-86 287.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Pox_A6 PF04924.7 KFM12503.1 - 0.14 10.9 0.1 0.22 10.3 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A6 protein VHS PF00790.14 KFM12504.1 - 2e-44 150.6 3.1 1.1e-43 148.2 0.0 2.7 3 1 0 3 3 3 1 VHS domain GAT PF03127.9 KFM12504.1 - 3e-25 88.1 4.5 3e-25 88.1 3.1 2.1 2 0 0 2 2 2 1 GAT domain DUF2959 PF11172.3 KFM12504.1 - 0.00033 20.4 0.7 0.00058 19.6 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2959) CR6_interact PF10147.4 KFM12504.1 - 0.022 14.0 3.7 0.036 13.3 2.5 1.3 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Hemagglutinin PF00509.13 KFM12504.1 - 0.033 12.3 0.1 0.44 8.6 0.1 2.0 2 0 0 2 2 2 0 Haemagglutinin SRP_SPB PF02978.14 KFM12504.1 - 0.22 11.8 1.9 0.45 10.7 1.3 1.5 1 0 0 1 1 1 0 Signal peptide binding domain 4HB_MCP_1 PF12729.2 KFM12504.1 - 1.8 7.8 9.0 6.5 6.0 5.3 2.4 1 1 2 3 3 3 0 Four helix bundle sensory module for signal transduction FUSC-like PF12805.2 KFM12504.1 - 1.8 7.3 5.7 5.4 5.8 0.3 2.2 1 1 0 2 2 2 0 FUSC-like inner membrane protein yccS PspB PF06667.7 KFM12504.1 - 2.5 8.1 5.0 2 8.4 0.2 2.9 1 1 2 3 3 3 0 Phage shock protein B Occludin_ELL PF07303.8 KFM12504.1 - 2.5 8.8 7.9 1.4 9.6 3.1 2.3 3 0 0 3 3 3 0 Occludin homology domain FliT PF05400.8 KFM12504.1 - 9.2 6.7 11.8 1.5 9.2 1.7 2.8 1 1 0 2 2 2 0 Flagellar protein FliT COG7 PF10191.4 KFM12505.1 - 1.8e-296 985.1 20.2 2e-296 985.0 14.0 1.0 1 0 0 1 1 1 1 Golgi complex component 7 (COG7) ICE2 PF08426.5 KFM12505.1 - 0.018 13.6 0.6 0.032 12.8 0.4 1.3 1 0 0 1 1 1 0 ICE2 DUF3014 PF11219.3 KFM12505.1 - 0.036 13.9 0.5 0.17 11.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3014) FlgN PF05130.7 KFM12505.1 - 0.051 13.8 10.6 0.82 9.9 2.9 3.2 2 1 0 2 2 2 0 FlgN protein ASC PF00858.19 KFM12506.1 - 4.1e-106 355.2 4.0 5.4e-106 354.8 2.8 1.2 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel ASC PF00858.19 KFM12507.1 - 5.5e-104 348.2 11.6 6.5e-104 348.0 8.0 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel UCH PF00443.24 KFM12508.1 - 5.3e-45 153.6 0.0 1.2e-44 152.5 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFM12508.1 - 1e-11 44.8 0.0 1.9e-09 37.4 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF2296 PF10058.4 KFM12508.1 - 0.019 14.7 1.5 6.5 6.5 0.0 2.7 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) zf-MIZ PF02891.15 KFM12508.1 - 0.33 10.4 9.3 0.33 10.4 3.6 2.7 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-RING_4 PF14570.1 KFM12508.1 - 0.93 9.1 4.4 2.5 7.7 0.9 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Sulfotransfer_1 PF00685.22 KFM12509.1 - 1.1e-34 119.9 0.0 1.2e-34 119.7 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_2 PF03567.9 KFM12509.1 - 0.013 15.2 0.1 0.083 12.5 0.0 2.0 2 0 0 2 2 2 0 Sulfotransferase family Sulfotransfer_1 PF00685.22 KFM12510.1 - 3.9e-33 114.8 0.0 4.6e-33 114.6 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_2 PF03567.9 KFM12510.1 - 0.0026 17.4 0.0 0.044 13.4 0.0 2.1 2 0 0 2 2 2 1 Sulfotransferase family Cupin_8 PF13621.1 KFM12511.1 - 9.8e-48 162.8 0.2 1.2e-47 162.5 0.1 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KFM12511.1 - 2.6e-07 30.2 0.1 7.1e-07 28.7 0.0 1.6 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.17 KFM12511.1 - 0.0098 16.1 0.1 0.047 13.9 0.0 2.0 1 1 0 1 1 1 1 JmjC domain, hydroxylase SMC_Nse1 PF07574.8 KFM12512.1 - 1.5e-39 135.6 1.9 6.2e-39 133.7 1.3 1.8 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 KFM12512.1 - 5.8e-11 42.2 9.6 5.8e-11 42.2 6.7 2.4 3 0 0 3 3 3 1 RING-like domain zf-C3HC4_2 PF13923.1 KFM12512.1 - 0.00031 20.6 9.8 0.00073 19.5 6.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF1390 PF07150.6 KFM12512.1 - 0.013 14.8 0.5 0.025 13.9 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) zf-C3HC4 PF00097.20 KFM12512.1 - 0.019 14.6 9.8 0.019 14.6 6.8 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CAF1 PF04857.15 KFM12512.1 - 0.065 12.5 0.1 0.082 12.2 0.1 1.2 1 0 0 1 1 1 0 CAF1 family ribonuclease DAP3 PF10236.4 KFM12512.1 - 0.079 11.8 0.6 0.14 11.0 0.4 1.3 1 1 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 TyeA PF09059.5 KFM12512.1 - 0.1 12.5 0.1 0.25 11.2 0.0 1.7 1 1 0 1 1 1 0 TyeA Multi-haem_cyto PF13447.1 KFM12512.1 - 0.11 11.5 8.1 0.45 9.5 5.3 2.0 1 1 1 2 2 2 0 Seven times multi-haem cytochrome CxxCH PHD PF00628.24 KFM12512.1 - 0.26 11.0 10.7 0.16 11.7 5.8 1.9 2 0 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.1 KFM12512.1 - 1.5 8.6 9.8 1.3 8.8 4.4 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 PhnA_Zn_Ribbon PF08274.7 KFM12512.1 - 1.5 8.6 5.5 7.6 6.4 0.5 3.5 3 0 0 3 3 3 0 PhnA Zinc-Ribbon IL4Ra_N PF09238.5 KFM12513.1 - 1.1e-31 108.7 0.9 1.1e-31 108.7 0.7 1.9 2 0 0 2 2 2 1 Interleukin-4 receptor alpha chain, N-terminal fn3 PF00041.16 KFM12513.1 - 5.1e-05 23.3 1.0 0.00022 21.2 0.5 2.1 2 0 0 2 2 2 1 Fibronectin type III domain IL6Ra-bind PF09240.5 KFM12513.1 - 0.00015 21.8 0.6 0.0003 20.8 0.4 1.5 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding EpoR_lig-bind PF09067.5 KFM12513.1 - 0.00047 20.1 0.8 0.00047 20.1 0.6 2.3 2 0 0 2 2 2 1 Erythropoietin receptor, ligand binding TTSSLRR PF12468.3 KFM12513.1 - 0.023 14.2 1.0 0.048 13.2 0.7 1.6 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein EpoR_lig-bind PF09067.5 KFM12515.1 - 0.0027 17.6 1.6 0.0047 16.9 0.3 1.9 2 0 0 2 2 2 1 Erythropoietin receptor, ligand binding fn3 PF00041.16 KFM12515.1 - 0.17 12.0 5.4 0.069 13.2 1.0 2.3 2 2 0 2 2 2 0 Fibronectin type III domain LRR19-TM PF15176.1 KFM12515.1 - 0.58 9.8 4.6 1.7 8.3 0.3 2.4 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain fn3 PF00041.16 KFM12516.1 - 0.014 15.4 0.6 0.025 14.7 0.4 1.5 1 0 0 1 1 1 0 Fibronectin type III domain Pkinase PF00069.20 KFM12517.1 - 3.4e-66 223.0 0.0 4.5e-66 222.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM12517.1 - 3.9e-34 117.9 0.0 5.3e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH_3 PF14593.1 KFM12517.1 - 7.6e-30 102.8 0.0 1.5e-29 101.9 0.0 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 KFM12517.1 - 2e-07 30.2 0.0 3.2e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFM12517.1 - 0.0032 16.5 0.0 0.0054 15.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFM12517.1 - 0.0096 15.6 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family YukC PF10140.4 KFM12517.1 - 0.038 12.5 0.0 0.056 12.0 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC BTB_2 PF02214.17 KFM12518.1 - 3.1e-11 43.3 0.0 5.2e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KFM12518.1 - 0.012 15.5 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain DUF4206 PF13901.1 KFM12518.1 - 0.054 13.0 0.1 0.069 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) UQ_con PF00179.21 KFM12519.1 - 9.8e-49 164.3 0.0 1.1e-48 164.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFM12519.1 - 0.00018 21.2 0.0 0.00021 21.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B DUF367 PF04034.8 KFM12520.1 - 3.9e-52 175.1 0.0 5.1e-52 174.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 KFM12520.1 - 8.5e-13 47.6 0.5 1.7e-12 46.6 0.3 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI PRKCSH_1 PF13015.1 KFM12521.1 - 4.4e-10 39.2 0.3 4e-09 36.1 0.0 2.2 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 KFM12521.1 - 7.7e-07 29.8 3.2 7.7e-07 29.8 2.2 2.3 2 2 1 3 3 3 1 Glucosidase II beta subunit-like protein DUF4582 PF15189.1 KFM12521.1 - 0.00032 19.9 1.1 0.00061 19.0 0.7 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4582) RraB PF06877.6 KFM12521.1 - 0.045 14.3 0.8 0.081 13.5 0.6 1.4 1 0 0 1 1 1 0 Regulator of ribonuclease activity B CIMR PF00878.13 KFM12521.1 - 0.055 13.2 0.1 0.19 11.4 0.0 1.8 2 0 0 2 2 2 0 Cation-independent mannose-6-phosphate receptor repeat YscO PF07321.7 KFM12521.1 - 0.21 11.3 5.5 0.31 10.8 3.8 1.2 1 0 0 1 1 1 0 Type III secretion protein YscO Transposase_22 PF02994.9 KFM12521.1 - 0.38 9.1 6.5 0.49 8.8 4.5 1.1 1 0 0 1 1 1 0 L1 transposable element zf-CCCH PF00642.19 KFM12522.1 - 2.7e-06 26.9 7.8 1.9e-05 24.1 1.6 6.4 7 0 0 7 7 7 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Filament PF00038.16 KFM12522.1 - 0.012 15.0 6.7 0.019 14.4 4.6 1.2 1 0 0 1 1 1 0 Intermediate filament protein Mnd1 PF03962.10 KFM12522.1 - 0.021 14.4 7.1 0.062 12.9 5.1 1.5 2 0 0 2 2 2 0 Mnd1 family DUF342 PF03961.8 KFM12522.1 - 0.047 12.1 0.1 0.064 11.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Borrelia_P83 PF05262.6 KFM12522.1 - 8 4.6 12.0 12 4.0 8.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein zf-C2H2_4 PF13894.1 KFM12523.1 - 4.9e-07 29.6 118.4 0.015 15.6 4.6 14.6 14 0 0 14 14 14 9 C2H2-type zinc finger zf-C2H2 PF00096.21 KFM12523.1 - 0.00062 19.9 13.6 0.0015 18.7 5.2 14.8 16 0 0 16 16 16 9 Zinc finger, C2H2 type zf-met PF12874.2 KFM12523.1 - 0.003 17.7 1.4 0.003 17.7 0.9 10.2 10 0 0 10 10 10 3 Zinc-finger of C2H2 type Peptidase_M48 PF01435.13 KFM12524.1 - 3.3e-77 259.0 0.0 4.3e-77 258.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M48 DUF4344 PF14247.1 KFM12524.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4344) Amino_oxidase PF01593.19 KFM12525.1 - 4.8e-164 546.7 0.0 6.1e-164 546.3 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 KFM12525.1 - 3.5e-20 71.9 0.2 3.8e-19 68.5 0.0 2.6 3 0 0 3 3 3 1 SWIRM domain NAD_binding_8 PF13450.1 KFM12525.1 - 7e-15 54.8 0.5 1.5e-14 53.7 0.4 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFM12525.1 - 9e-08 31.4 0.0 5e-07 28.9 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFM12525.1 - 3.3e-07 30.6 0.6 1.4e-05 25.3 0.2 3.3 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFM12525.1 - 4.1e-05 22.6 1.4 5.5e-05 22.1 0.4 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KFM12525.1 - 6.9e-05 22.8 0.1 0.00025 20.9 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KFM12525.1 - 9.6e-05 22.0 0.3 0.00023 20.7 0.2 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 KFM12525.1 - 0.00055 20.0 1.9 0.0018 18.4 0.1 2.5 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KFM12525.1 - 0.00057 19.0 0.5 0.001 18.2 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KFM12525.1 - 0.00077 18.0 0.4 0.00077 18.0 0.3 2.2 1 1 1 2 2 2 1 HI0933-like protein Thi4 PF01946.12 KFM12525.1 - 0.0011 18.1 0.1 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family 2-Hacid_dh_C PF02826.14 KFM12525.1 - 0.021 13.9 0.2 0.08 12.0 0.1 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 KFM12525.1 - 0.023 13.8 4.5 0.016 14.2 1.4 1.9 1 1 1 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 KFM12525.1 - 0.049 12.4 5.5 0.1 11.4 0.2 2.2 1 1 0 2 2 2 0 Glucose inhibited division protein A IlvN PF07991.7 KFM12525.1 - 0.11 11.9 0.8 0.4 10.0 0.5 2.0 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain DUF1465 PF07323.7 KFM12525.1 - 0.11 12.0 3.1 0.16 11.5 0.7 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1465) Lycopene_cycl PF05834.7 KFM12525.1 - 0.19 10.5 0.3 0.49 9.2 0.1 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein MutS_IV PF05190.13 KFM12525.1 - 0.21 11.7 3.5 1.3 9.2 0.4 2.6 2 0 0 2 2 2 0 MutS family domain IV DivIC PF04977.10 KFM12525.1 - 1.3 8.5 7.5 16 5.0 0.1 2.8 2 0 0 2 2 2 0 Septum formation initiator V_ATPase_I PF01496.14 KFM12525.1 - 1.8 6.3 4.8 3 5.5 3.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nnf1 PF03980.9 KFM12525.1 - 2 8.4 10.1 4.6 7.2 7.0 1.6 1 0 0 1 1 1 0 Nnf1 Viral_P18 PF04521.8 KFM12525.1 - 7 6.1 7.9 2.3 7.6 2.6 2.1 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Snapin_Pallidin PF14712.1 KFM12525.1 - 8.2 6.8 10.4 3.8 7.8 2.9 2.4 1 1 0 2 2 2 0 Snapin/Pallidin DUF3782 PF12644.2 KFM12525.1 - 8.6 6.2 9.0 2.7e+03 -1.8 6.2 3.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) Pantoate_ligase PF02569.10 KFM12526.1 - 0.0055 15.4 3.1 0.015 14.1 2.1 1.7 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase HD_assoc PF13286.1 KFM12526.1 - 0.022 15.0 0.3 0.11 12.7 0.2 2.3 1 0 0 1 1 1 0 Phosphohydrolase-associated domain 7tm_1 PF00001.16 KFM12527.1 - 1.3e-86 289.8 14.5 1.6e-86 289.6 10.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM12527.1 - 1.4e-11 44.0 10.3 3.6e-11 42.6 7.2 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM12527.1 - 0.00076 18.6 11.9 0.00076 18.6 8.2 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx RRM_1 PF00076.17 KFM12530.1 - 2.6e-45 151.8 0.8 2.3e-15 55.9 0.3 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM12530.1 - 1.2e-35 121.2 0.1 1.7e-12 47.1 0.0 3.7 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM12530.1 - 3.2e-18 65.3 0.1 1.1e-05 25.2 0.1 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KFM12530.1 - 0.00012 21.7 1.2 0.46 10.2 0.2 3.9 1 1 2 3 3 3 1 Limkain b1 Nup35_RRM_2 PF14605.1 KFM12530.1 - 0.0085 15.8 0.0 1.8 8.3 0.0 3.3 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Calcipressin PF04847.7 KFM12530.1 - 0.012 15.2 0.2 0.28 10.7 0.1 2.6 2 1 1 3 3 3 0 Calcipressin IATP PF04568.7 KFM12531.1 - 6e-08 32.6 11.5 6e-08 32.6 8.0 1.6 1 1 1 2 2 2 1 Mitochondrial ATPase inhibitor, IATP DivIC PF04977.10 KFM12531.1 - 0.0064 15.9 5.1 0.0071 15.8 3.3 1.4 1 1 0 1 1 1 1 Septum formation initiator Phage_lysis PF03245.8 KFM12531.1 - 0.018 15.0 3.6 0.018 14.9 2.5 1.1 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein Fib_alpha PF08702.5 KFM12531.1 - 0.02 15.0 3.7 0.02 15.0 2.6 1.0 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.3 KFM12531.1 - 0.025 14.3 9.1 0.037 13.8 6.3 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding THOC7 PF05615.8 KFM12531.1 - 0.029 14.6 7.5 0.031 14.5 5.2 1.1 1 0 0 1 1 1 0 Tho complex subunit 7 DUF3450 PF11932.3 KFM12531.1 - 0.037 13.3 2.1 0.036 13.3 1.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) FliJ PF02050.11 KFM12531.1 - 0.039 14.0 3.8 0.042 13.9 2.6 1.2 1 0 0 1 1 1 0 Flagellar FliJ protein FlaC_arch PF05377.6 KFM12531.1 - 0.069 13.0 1.4 0.13 12.1 1.0 1.6 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) Prefoldin_2 PF01920.15 KFM12531.1 - 0.092 12.5 8.7 0.1 12.4 6.0 1.1 1 0 0 1 1 1 0 Prefoldin subunit Sipho_Gp157 PF05565.6 KFM12531.1 - 0.094 12.2 6.6 0.094 12.2 4.6 1.0 1 0 0 1 1 1 0 Siphovirus Gp157 DUF2968 PF11180.3 KFM12531.1 - 0.1 11.9 2.1 0.11 11.9 1.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Spc7 PF08317.6 KFM12531.1 - 0.12 10.9 6.3 0.12 11.0 4.4 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein FlxA PF14282.1 KFM12531.1 - 0.13 12.1 1.4 0.23 11.4 0.8 1.3 1 1 0 1 1 1 0 FlxA-like protein Kinesin-relat_1 PF12711.2 KFM12531.1 - 0.14 12.6 4.9 0.17 12.2 3.4 1.4 1 0 0 1 1 1 0 Kinesin motor ADIP PF11559.3 KFM12531.1 - 0.23 11.3 6.7 0.24 11.2 4.6 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4140 PF13600.1 KFM12531.1 - 0.24 11.8 4.3 0.28 11.6 3.0 1.1 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DNA_pol3_theta PF06440.6 KFM12531.1 - 0.25 10.9 1.5 0.29 10.7 1.0 1.1 1 0 0 1 1 1 0 DNA polymerase III, theta subunit DNA_Packaging_2 PF11123.3 KFM12531.1 - 0.26 11.2 1.8 0.33 10.8 1.2 1.5 1 1 0 1 1 1 0 DNA packaging protein Lipoprotein_20 PF13942.1 KFM12531.1 - 0.29 10.6 6.1 0.3 10.6 4.2 1.0 1 0 0 1 1 1 0 YfhG lipoprotein Bap31 PF05529.7 KFM12531.1 - 0.3 10.5 6.8 0.29 10.5 4.7 1.0 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF1192 PF06698.6 KFM12531.1 - 0.3 10.9 3.4 0.46 10.3 2.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) Borrelia_P83 PF05262.6 KFM12531.1 - 0.32 9.2 8.1 0.31 9.2 5.6 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2674 PF10879.3 KFM12531.1 - 0.33 10.7 2.5 0.39 10.4 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2674) DUF1640 PF07798.6 KFM12531.1 - 0.36 10.8 5.6 0.38 10.7 3.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF812 PF05667.6 KFM12531.1 - 0.4 9.1 5.5 0.4 9.1 3.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) bZIP_1 PF00170.16 KFM12531.1 - 0.42 10.6 6.4 0.69 9.9 4.5 1.5 1 1 0 1 1 1 0 bZIP transcription factor Val_tRNA-synt_C PF10458.4 KFM12531.1 - 0.47 10.5 7.6 0.12 12.4 2.2 1.9 1 1 1 2 2 2 0 Valyl tRNA synthetase tRNA binding arm ATG16 PF08614.6 KFM12531.1 - 0.48 10.2 6.8 0.47 10.2 4.7 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF1409 PF07197.7 KFM12531.1 - 0.6 10.2 4.2 0.75 9.9 2.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1409) Dzip-like_N PF13815.1 KFM12531.1 - 0.72 9.6 6.5 0.78 9.5 4.5 1.1 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Spectrin PF00435.16 KFM12531.1 - 0.86 9.9 6.7 0.89 9.8 4.7 1.0 1 0 0 1 1 1 0 Spectrin repeat DUF4200 PF13863.1 KFM12531.1 - 0.88 9.5 12.2 0.96 9.4 8.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) PCRF PF03462.13 KFM12531.1 - 0.91 9.2 3.5 0.86 9.3 2.4 1.1 1 0 0 1 1 1 0 PCRF domain DUF342 PF03961.8 KFM12531.1 - 1.1 7.6 5.8 1.1 7.5 4.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Pox_A_type_inc PF04508.7 KFM12531.1 - 1.2 9.1 9.5 0.46 10.3 2.6 2.7 2 1 0 2 2 2 0 Viral A-type inclusion protein repeat DUF2681 PF10883.3 KFM12531.1 - 1.2 9.3 4.5 3.6 7.8 3.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) TMPIT PF07851.8 KFM12531.1 - 1.3 8.0 4.7 1.3 8.0 3.2 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF4446 PF14584.1 KFM12531.1 - 1.4 8.7 3.7 1.3 8.8 2.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) ABC_tran_2 PF12848.2 KFM12531.1 - 1.4 8.7 9.6 2.6 7.9 6.6 1.4 1 1 0 1 1 1 0 ABC transporter G-gamma PF00631.17 KFM12531.1 - 1.6 8.5 5.1 0.18 11.5 1.0 1.4 2 0 0 2 2 1 0 GGL domain Atg14 PF10186.4 KFM12531.1 - 1.6 7.6 9.2 1.6 7.6 6.4 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 GrpE PF01025.14 KFM12531.1 - 2 7.9 6.3 2 7.9 4.4 1.0 1 0 0 1 1 1 0 GrpE DUF3987 PF13148.1 KFM12531.1 - 2.1 6.7 7.1 2.2 6.7 4.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) IMD PF08397.6 KFM12531.1 - 2.5 7.3 8.6 2.4 7.3 5.9 1.0 1 0 0 1 1 1 0 IRSp53/MIM homology domain IncA PF04156.9 KFM12531.1 - 3.6 7.1 6.9 3.6 7.1 4.8 1.1 1 0 0 1 1 1 0 IncA protein DUF612 PF04747.7 KFM12531.1 - 3.9 6.2 9.8 3.6 6.3 6.8 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF612 Cep57_MT_bd PF06657.8 KFM12531.1 - 4.1 7.4 9.5 23 5.0 6.6 1.9 1 1 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 XhlA PF10779.4 KFM12531.1 - 4.3 7.3 7.0 4.9 7.1 4.8 1.3 1 0 0 1 1 1 0 Haemolysin XhlA DUF4355 PF14265.1 KFM12531.1 - 4.6 7.1 10.0 5.2 7.0 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) DUF4078 PF13300.1 KFM12531.1 - 4.7 7.3 9.2 5.1 7.2 6.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4078) DUF3395 PF11875.3 KFM12531.1 - 6.2 6.4 6.9 6.1 6.4 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) APG6 PF04111.7 KFM12531.1 - 7.1 5.5 7.7 7.1 5.5 5.3 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 CENP-Q PF13094.1 KFM12531.1 - 8.9 6.3 9.0 10 6.1 6.3 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DnaJ PF00226.26 KFM12532.1 - 7.7e-19 67.1 1.7 2.5e-18 65.5 1.2 1.9 1 0 0 1 1 1 1 DnaJ domain DUF4320 PF14208.1 KFM12532.1 - 0.023 14.6 1.6 0.039 13.8 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4320) RPT PF13446.1 KFM12532.1 - 0.044 13.2 0.1 0.13 11.7 0.1 1.8 1 0 0 1 1 1 0 A repeated domain in UCH-protein Cytochrom_C1 PF02167.10 KFM12532.1 - 0.81 9.3 7.0 1.7 8.2 0.1 2.2 2 0 0 2 2 2 0 Cytochrome C1 family AAA_11 PF13086.1 KFM12532.1 - 2.7 7.4 7.8 3.5 7.1 5.4 1.3 1 0 0 1 1 1 0 AAA domain 7tm_1 PF00001.16 KFM12533.1 - 6.9e-47 159.7 25.8 9.5e-47 159.2 17.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Serpentine_r_xa PF03383.10 KFM12533.1 - 0.0039 16.9 27.2 0.015 15.0 0.5 3.1 2 1 0 3 3 3 3 Caenorhabditis serpentine receptor-like protein, class xa Proho_convert PF12177.3 KFM12534.1 - 0.028 13.9 0.1 0.062 12.8 0.1 1.5 1 0 0 1 1 1 0 Prohormone convertase enzyme DUF2592 PF10766.4 KFM12534.1 - 0.051 12.9 0.1 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2592) XK-related PF09815.4 KFM12535.1 - 3.1e-84 282.8 9.6 3.5e-84 282.6 6.7 1.0 1 0 0 1 1 1 1 XK-related protein DUF4229 PF14012.1 KFM12535.1 - 1.2 9.0 6.6 4.1 7.3 4.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) Metallophos PF00149.23 KFM12536.1 - 3.5e-12 46.1 0.9 4.6e-12 45.7 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RPA_C PF08784.6 KFM12537.1 - 9.2e-26 90.2 0.1 2.8e-25 88.6 0.0 1.8 1 1 1 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 KFM12537.1 - 0.0017 18.1 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain LexA_DNA_bind PF01726.11 KFM12537.1 - 0.0037 16.7 0.0 0.0097 15.4 0.0 1.7 1 0 0 1 1 1 1 LexA DNA binding domain MarR_2 PF12802.2 KFM12537.1 - 0.072 12.7 0.0 0.28 10.8 0.0 1.9 2 0 0 2 2 2 0 MarR family UBN2 PF14223.1 KFM12537.1 - 0.086 12.6 0.2 8.1 6.2 0.0 2.2 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type TBD PF12845.2 KFM12537.1 - 0.091 12.3 0.5 0.33 10.5 0.1 2.1 2 0 0 2 2 2 0 TBD domain Syntaxin_2 PF14523.1 KFM12538.1 - 2.9e-22 78.6 13.4 7.2e-22 77.3 6.0 2.3 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 KFM12538.1 - 3.6e-21 74.6 4.5 3.6e-21 74.6 3.1 2.1 2 0 0 2 2 2 1 SNARE domain Herpes_US9 PF06072.6 KFM12538.1 - 0.00054 19.7 0.1 0.0012 18.5 0.0 1.6 1 0 0 1 1 1 1 Alphaherpesvirus tegument protein US9 TBPIP PF07106.8 KFM12538.1 - 0.0081 15.7 4.8 0.0081 15.7 3.3 2.1 2 0 0 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ATG16 PF08614.6 KFM12538.1 - 0.027 14.3 2.8 0.027 14.3 1.9 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) GvpK PF05121.7 KFM12538.1 - 0.61 9.9 5.6 1.5 8.6 0.1 3.1 2 1 0 2 2 2 0 Gas vesicle protein K Synaptobrevin PF00957.16 KFM12538.1 - 0.75 9.4 10.0 0.25 10.9 1.8 2.8 2 1 0 2 2 2 0 Synaptobrevin DUF3782 PF12644.2 KFM12538.1 - 1.7 8.4 4.0 20 5.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) DUF2951 PF11166.3 KFM12538.1 - 8.2 6.3 11.9 0.11 12.3 0.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2951) CITED PF04487.7 KFM12539.1 - 3.2e-85 285.7 15.3 3.6e-85 285.5 10.6 1.0 1 0 0 1 1 1 1 CITED DUF39 PF01837.11 KFM12539.1 - 0.052 12.1 0.0 0.069 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF39 CTP_synth_N PF06418.9 KFM12540.1 - 1.1e-124 414.9 0.1 1.6e-124 414.5 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 KFM12540.1 - 5.7e-52 175.9 0.0 9.4e-52 175.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KFM12540.1 - 3.8e-10 39.5 0.1 8.4e-10 38.4 0.1 1.7 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 KFM12540.1 - 0.0059 16.0 0.0 0.012 15.0 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Transket_pyr PF02779.19 KFM12540.1 - 0.016 14.6 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Transketolase, pyrimidine binding domain DUF3588 PF12140.3 KFM12541.1 - 5.7e-48 161.8 0.3 8.6e-48 161.3 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3588) SAM_1 PF00536.25 KFM12541.1 - 6.6e-16 58.2 0.1 1.3e-15 57.3 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFM12541.1 - 1.3e-07 31.2 0.0 3.1e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 KFM12541.1 - 0.00033 20.3 0.0 0.00059 19.5 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Endothelin PF00322.12 KFM12542.1 - 1.4e-19 69.0 14.9 6e-19 66.9 3.0 2.3 2 0 0 2 2 2 2 Endothelin family Phage_fiber_2 PF03406.8 KFM12544.1 - 0.14 11.7 0.4 0.23 11.1 0.2 1.3 1 0 0 1 1 1 0 Phage tail fibre repeat Serinc PF03348.10 KFM12545.1 - 2e-163 544.0 17.7 2.3e-163 543.8 12.3 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) ISK_Channel PF02060.10 KFM12546.1 - 7.9e-09 35.1 0.1 1e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Slow voltage-gated potassium channel Granin PF01271.12 KFM12547.1 - 2.8e-152 508.4 38.9 3.1e-152 508.3 27.0 1.0 1 0 0 1 1 1 1 Granin (chromogranin or secretogranin) IF2_N PF04760.10 KFM12547.1 - 0.031 13.9 2.3 2.6 7.7 0.1 3.2 3 0 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region DUF4303 PF14136.1 KFM12547.1 - 0.073 12.7 3.3 0.37 10.4 0.9 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4303) Clat_adaptor_s PF01217.15 KFM12548.1 - 6.6e-59 197.6 3.2 7.4e-59 197.5 2.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain WD40 PF00400.27 KFM12549.1 - 9.9e-23 79.1 22.9 1.3e-08 34.3 0.9 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat FYVE PF01363.16 KFM12549.1 - 4.9e-15 55.1 7.9 4.9e-15 55.1 5.5 1.7 2 0 0 2 2 2 1 FYVE zinc finger Nucleoporin_N PF08801.6 KFM12549.1 - 0.00012 21.0 3.4 0.8 8.3 0.0 4.0 1 1 1 3 3 3 2 Nup133 N terminal like Lactonase PF10282.4 KFM12549.1 - 0.064 12.3 0.0 1.9 7.4 0.0 2.1 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller FYVE_2 PF02318.11 KFM12549.1 - 1.6 8.6 8.3 4.8 7.0 5.7 1.8 1 1 0 1 1 1 0 FYVE-type zinc finger zf-B_box PF00643.19 KFM12549.1 - 4.8 7.1 16.0 0.11 12.4 0.7 4.4 5 0 0 5 5 5 0 B-box zinc finger Serpin PF00079.15 KFM12550.1 - 2.5e-110 369.1 0.0 2.8e-110 368.9 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) FAM124 PF15067.1 KFM12551.1 - 1.3e-102 342.1 0.2 1.5e-102 342.0 0.1 1.0 1 0 0 1 1 1 1 FAM124 family Maelstrom PF13017.1 KFM12551.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 piRNA pathway germ-plasm component Cullin PF00888.17 KFM12552.1 - 2.1e-202 673.8 10.7 2.5e-202 673.5 7.4 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KFM12552.1 - 5.9e-30 102.8 2.0 2.5e-29 100.8 1.4 2.2 1 0 0 1 1 1 1 Cullin protein neddylation domain Guanylate_cyc PF00211.15 KFM12553.1 - 8.3e-68 227.3 0.1 1.4e-67 226.6 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.9 KFM12553.1 - 1.5e-49 168.1 13.8 2.4e-49 167.5 7.0 2.5 2 1 0 2 2 2 1 Heme NO binding associated HNOB PF07700.10 KFM12553.1 - 2.5e-45 154.0 0.0 2.4e-44 150.9 0.0 2.2 1 1 0 1 1 1 1 Heme NO binding DIRP PF06584.8 KFM12553.1 - 0.088 12.6 1.4 0.34 10.7 0.3 2.3 2 0 0 2 2 2 0 DIRP Ded_cyto PF06920.8 KFM12554.1 - 1.9e-65 219.4 2.0 5.1e-65 218.0 1.4 1.8 1 0 0 1 1 1 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 KFM12554.1 - 3.4e-56 189.7 1.2 7.4e-56 188.7 0.1 2.2 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.3 KFM12554.1 - 5.9e-31 106.1 0.5 1.5e-30 104.8 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3398) PH PF00169.24 KFM12554.1 - 4e-11 43.0 2.4 1.7e-10 41.0 0.4 3.1 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 KFM12554.1 - 0.0037 17.4 0.1 0.027 14.6 0.1 2.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_10 PF15411.1 KFM12554.1 - 0.0054 16.8 0.0 0.018 15.2 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 KFM12554.1 - 0.027 14.7 0.5 0.13 12.5 0.4 2.3 1 0 0 1 1 1 0 Pleckstrin homology domain NYAP_N PF15439.1 KFM12555.1 - 1.1e-120 403.3 51.8 4.8e-84 282.7 15.6 3.4 3 0 0 3 3 3 2 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter NYAP_C PF15452.1 KFM12555.1 - 3.3e-13 49.3 7.8 5.9e-13 48.5 5.4 1.4 1 0 0 1 1 1 1 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter IRS PF02174.12 KFM12556.1 - 1.6e-29 101.4 0.0 2.6e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 PTB domain (IRS-1 type) PH PF00169.24 KFM12556.1 - 2.2e-14 53.5 0.1 5.3e-14 52.2 0.1 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KFM12556.1 - 0.00038 20.6 0.1 0.00074 19.7 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Mcp5_PH PF12814.2 KFM12556.1 - 0.082 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology Rhomboid PF01694.17 KFM12557.1 - 7.7e-15 55.1 5.7 1.7e-14 54.0 3.9 1.5 1 0 0 1 1 1 1 Rhomboid family COPI_assoc PF08507.5 KFM12557.1 - 7 6.3 9.9 0.053 13.2 0.7 2.0 3 0 0 3 3 3 0 COPI associated protein Collagen PF01391.13 KFM12558.1 - 1.7e-189 613.6 697.8 3.5e-10 39.2 15.0 28.1 4 4 21 25 25 25 24 Collagen triple helix repeat (20 copies) C4 PF01413.14 KFM12558.1 - 1.3e-85 282.8 5.2 8.7e-45 151.2 0.9 2.2 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen Collagen PF01391.13 KFM12559.1 - 2.5e-181 587.4 688.4 1.2e-09 37.5 20.5 27.1 5 5 20 25 25 25 25 Collagen triple helix repeat (20 copies) C4 PF01413.14 KFM12559.1 - 1.1e-90 299.1 4.2 7.1e-47 158.0 0.2 2.2 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen Miff PF05644.6 KFM12560.1 - 4.9e-95 317.8 6.4 1.6e-94 316.1 4.4 1.7 1 1 0 1 1 1 1 Mitochondrial and peroxisomal fission factor Mff dsrm PF00035.20 KFM12561.1 - 0.00065 20.2 0.0 0.0013 19.2 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif ArfGap PF01412.13 KFM12562.1 - 8.1e-12 44.9 0.0 1.6e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Folate_carrier PF01770.13 KFM12563.1 - 2.5e-178 592.8 13.5 2.9e-178 592.5 9.4 1.0 1 0 0 1 1 1 1 Reduced folate carrier MFS_1 PF07690.11 KFM12563.1 - 2.4e-11 42.9 18.1 3.9e-11 42.2 12.6 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Folate_carrier PF01770.13 KFM12564.1 - 2.1e-178 593.0 18.0 2.5e-178 592.8 12.5 1.0 1 0 0 1 1 1 1 Reduced folate carrier MFS_1 PF07690.11 KFM12564.1 - 6e-12 44.9 18.1 9.1e-12 44.3 12.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily IL8 PF00048.15 KFM12565.1 - 4.6e-17 61.7 0.0 5.4e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like WD40 PF00400.27 KFM12566.1 - 2e-86 281.0 18.5 2.7e-11 42.9 0.1 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 KFM12566.1 - 2.3e-07 29.3 3.1 0.16 10.0 0.0 5.7 1 1 3 5 5 5 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KFM12566.1 - 0.0016 17.9 0.1 0.29 10.5 0.0 2.6 2 2 0 2 2 2 2 PQQ-like domain DUF1258 PF06869.7 KFM12566.1 - 0.0031 16.6 2.8 0.096 11.7 0.1 3.2 2 1 2 4 4 4 2 Protein of unknown function (DUF1258) AKAP_110 PF05716.8 KFM12567.1 - 1.4e-10 39.8 0.0 3e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 A-kinase anchor protein 110 kDa (AKAP 110) PID_2 PF14719.1 KFM12568.1 - 2.2e-18 66.5 0.5 3.8e-18 65.7 0.4 1.3 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID PF00640.18 KFM12568.1 - 1.3e-06 28.4 1.5 1.9e-06 27.8 1.0 1.5 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) EGF PF00008.22 KFM12569.1 - 1.8e-54 181.1 125.6 2.9e-08 33.5 7.6 9.6 9 0 0 9 9 9 9 EGF-like domain EGF_2 PF07974.8 KFM12569.1 - 9.1e-19 67.3 152.3 0.00071 19.6 6.4 9.6 9 0 0 9 9 9 9 EGF-like domain hEGF PF12661.2 KFM12569.1 - 8.8e-16 56.8 78.6 0.0081 16.1 2.2 10.1 9 0 0 9 9 9 7 Human growth factor-like EGF EGF_CA PF07645.10 KFM12569.1 - 4.4e-07 29.7 129.5 1.7e-05 24.7 5.3 9.7 3 1 6 9 9 9 6 Calcium-binding EGF domain EGF_3 PF12947.2 KFM12569.1 - 1.2e-06 28.3 115.6 0.0042 17.0 6.3 9.6 8 1 1 9 9 9 7 EGF domain FXa_inhibition PF14670.1 KFM12569.1 - 0.00027 20.9 117.4 0.0022 18.0 5.8 9.6 3 2 6 9 9 9 5 Coagulation Factor Xa inhibitory site Laminin_EGF PF00053.19 KFM12569.1 - 0.00062 19.6 117.5 0.89 9.5 4.2 9.4 3 1 6 9 9 9 5 Laminin EGF-like (Domains III and V) cEGF PF12662.2 KFM12569.1 - 0.28 10.8 83.8 0.11 12.1 1.0 9.9 9 0 0 9 9 9 0 Complement Clr-like EGF-like HECT PF00632.20 KFM12570.1 - 7.4e-95 317.7 0.7 1.7e-94 316.5 0.0 2.0 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) WWE PF02825.15 KFM12570.1 - 0.00029 20.1 0.1 0.00077 18.8 0.1 1.7 1 0 0 1 1 1 1 WWE domain F-box-like PF12937.2 KFM12571.1 - 5.7e-10 38.7 0.2 1e-09 37.9 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFM12571.1 - 5.2e-08 32.3 2.7 1.3e-07 31.1 0.5 2.5 2 1 1 3 3 3 1 F-box domain Tet_JBP PF12851.2 KFM12571.1 - 0.08 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily MFS_1 PF07690.11 KFM12572.1 - 9.3e-49 166.0 24.5 3.1e-40 137.9 14.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KFM12572.1 - 0.082 12.7 10.8 0.52 10.1 0.0 3.9 3 1 0 3 3 3 0 MFS_1 like family UPF0154 PF03672.8 KFM12572.1 - 0.31 10.6 2.6 2.2 7.9 0.4 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) zf-rbx1 PF12678.2 KFM12573.1 - 5.1e-14 52.1 15.9 5.8e-14 51.9 11.0 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KFM12573.1 - 1.3e-08 34.5 10.9 1.4e-08 34.4 7.6 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 KFM12573.1 - 2.2e-08 33.7 12.5 3.1e-08 33.2 8.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFM12573.1 - 1.5e-05 24.5 9.7 2.2e-05 24.0 6.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM12573.1 - 0.0014 18.2 13.6 0.0028 17.2 9.4 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM12573.1 - 0.0016 18.4 12.3 0.0018 18.2 8.1 1.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM12573.1 - 0.0026 17.4 12.2 0.0043 16.7 8.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.1 KFM12573.1 - 0.028 14.2 4.8 0.035 13.8 3.3 1.1 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Rad50_zn_hook PF04423.9 KFM12573.1 - 0.046 13.2 0.2 0.097 12.1 0.1 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif Zn_Tnp_IS1 PF03811.8 KFM12573.1 - 0.15 11.5 0.2 0.15 11.5 0.1 2.3 2 1 0 2 2 2 0 InsA N-terminal domain PHD PF00628.24 KFM12573.1 - 1.2 8.8 14.5 2.3 7.9 10.0 1.5 1 1 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.1 KFM12573.1 - 1.6 8.5 13.3 3.4 7.4 5.6 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.1 KFM12573.1 - 2.9 7.5 13.3 1.5 8.4 7.9 1.5 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Pkinase PF00069.20 KFM12574.1 - 1.9e-60 204.1 0.1 3e-60 203.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM12574.1 - 1.7e-33 115.7 0.2 4.4e-33 114.4 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase RGS PF00615.14 KFM12574.1 - 3.6e-13 49.6 5.4 5.8e-13 48.9 1.7 2.3 2 0 0 2 2 2 1 Regulator of G protein signaling domain Kinase-like PF14531.1 KFM12574.1 - 0.00079 18.4 0.0 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Na_K-ATPase PF00287.13 KFM12575.1 - 3.7e-98 327.8 0.1 4.1e-98 327.7 0.1 1.0 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain DP PF08781.5 KFM12576.1 - 1.2e-57 193.5 1.0 2.9e-57 192.3 0.7 1.6 1 0 0 1 1 1 1 Transcription factor DP E2F_TDP PF02319.15 KFM12576.1 - 4.6e-27 93.3 0.5 1e-26 92.2 0.3 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain FGGY_N PF00370.16 KFM12577.1 - 4.6e-38 130.9 0.0 1.4e-36 126.0 0.0 2.3 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 KFM12577.1 - 7.9e-31 107.2 0.0 1.7e-30 106.1 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain XRN_N PF03159.13 KFM12578.1 - 3.5e-91 304.8 0.1 8.2e-91 303.6 0.0 1.7 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus CH PF00307.26 KFM12579.1 - 1.5e-79 263.0 1.1 2.3e-22 79.0 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 KFM12579.1 - 1e-11 44.7 0.0 3.3e-11 43.1 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KFM12579.1 - 4.1e-09 35.0 1.1 1.9e-05 23.5 0.1 3.0 2 0 0 2 2 2 2 EF hand CAMSAP_CH PF11971.3 KFM12579.1 - 1.9e-06 27.4 0.1 0.00066 19.2 0.1 3.3 4 0 0 4 4 4 1 CAMSAP CH domain EF-hand_8 PF13833.1 KFM12579.1 - 0.00012 21.6 0.6 0.011 15.3 0.1 2.9 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KFM12579.1 - 0.00034 20.2 0.1 0.26 11.2 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 KFM12579.1 - 0.0013 17.9 2.3 0.02 14.2 0.0 3.2 3 0 0 3 3 3 1 EF hand TRP_2 PF08344.6 KFM12580.1 - 2.7e-27 94.4 2.6 6.2e-27 93.3 1.8 1.7 1 0 0 1 1 1 1 Transient receptor ion channel II Ion_trans PF00520.26 KFM12580.1 - 4.6e-20 71.7 16.4 1.1e-19 70.4 10.9 2.1 3 0 0 3 3 3 1 Ion transport protein Ank_2 PF12796.2 KFM12580.1 - 6.9e-08 32.7 1.0 2.8e-05 24.3 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFM12580.1 - 2.3e-06 27.9 0.3 0.021 15.3 0.0 2.9 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KFM12580.1 - 0.0011 18.6 0.2 0.48 10.3 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 KFM12580.1 - 0.004 17.3 0.1 2 8.7 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) DUF2407_C PF13373.1 KFM12580.1 - 0.018 14.9 0.1 0.15 11.9 0.0 2.5 2 0 0 2 2 2 0 DUF2407 C-terminal domain CUB PF00431.15 KFM12581.1 - 7.2e-62 206.3 0.0 3.3e-31 107.5 0.0 2.3 2 0 0 2 2 2 2 CUB domain NTR PF01759.16 KFM12581.1 - 2e-15 56.2 0.6 3.4e-15 55.5 0.0 1.7 2 0 0 2 2 2 1 UNC-6/NTR/C345C module CUB_2 PF02408.15 KFM12581.1 - 1.7e-08 34.0 0.2 0.00068 19.1 0.0 2.7 2 0 0 2 2 2 2 CUB-like domain TIMP PF00965.12 KFM12581.1 - 0.001 18.7 0.2 0.002 17.7 0.1 1.5 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase HlyIII PF03006.15 KFM12582.1 - 3e-21 75.8 8.4 5.2e-21 75.0 5.8 1.3 1 0 0 1 1 1 1 Haemolysin-III related Surp PF01805.15 KFM12583.1 - 2.1e-20 72.1 0.1 6.6e-20 70.5 0.1 1.9 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.17 KFM12583.1 - 7.7e-15 54.2 0.0 1.7e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM12583.1 - 3.1e-10 39.8 0.0 7.7e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) cwf21 PF08312.7 KFM12583.1 - 5e-09 35.8 4.1 5e-09 35.8 2.8 3.6 3 0 0 3 3 3 1 cwf21 domain CTK3 PF12243.3 KFM12583.1 - 4.2e-05 23.1 0.2 0.00012 21.7 0.0 1.8 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 RRM_5 PF13893.1 KFM12583.1 - 0.00022 20.9 0.0 0.00047 19.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 KFM12583.1 - 0.0067 16.6 0.5 0.05 13.8 0.1 2.7 2 0 0 2 2 2 1 RNA polymerase II-binding domain. Sulfotransfer_1 PF00685.22 KFM12584.1 - 5.5e-13 48.7 0.0 6.5e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Na_H_Exchanger PF00999.16 KFM12585.1 - 4.7e-79 265.6 25.9 7.9e-79 264.9 17.9 1.3 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family PIP49_C PF12260.3 KFM12586.1 - 3.8e-49 166.6 0.0 5.3e-49 166.1 0.0 1.2 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Scramblase PF03803.10 KFM12587.1 - 2.1e-84 282.0 0.2 2.3e-84 281.8 0.1 1.0 1 0 0 1 1 1 1 Scramblase FA_hydroxylase PF04116.8 KFM12588.1 - 1.3e-13 51.3 26.0 5e-13 49.4 15.4 2.2 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily LRR_4 PF12799.2 KFM12589.1 - 6.9e-12 44.7 22.6 8.1e-06 25.3 1.0 5.0 4 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM12589.1 - 1.2e-10 41.0 16.1 0.00034 20.2 0.1 3.9 3 1 1 4 4 4 3 Leucine rich repeat Ubiquitin_2 PF14560.1 KFM12589.1 - 2.7e-07 30.7 0.2 1.1e-06 28.8 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-like domain LRR_9 PF14580.1 KFM12589.1 - 3.2e-07 30.0 2.0 5.8e-05 22.7 0.0 3.1 1 1 2 3 3 3 1 Leucine-rich repeat LRR_6 PF13516.1 KFM12589.1 - 0.00017 21.2 14.8 3 8.1 0.1 6.4 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.28 KFM12589.1 - 0.0018 18.0 17.1 1.7 8.9 0.2 6.2 7 0 0 7 7 6 2 Leucine Rich Repeat LRR_7 PF13504.1 KFM12589.1 - 0.015 15.3 16.9 4.2 7.9 0.2 6.7 7 0 0 7 7 7 0 Leucine rich repeat ubiquitin PF00240.18 KFM12589.1 - 0.035 13.5 0.2 0.32 10.4 0.1 2.4 1 1 0 1 1 1 0 Ubiquitin family DUF104 PF01954.11 KFM12589.1 - 0.046 13.7 0.4 0.13 12.3 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF104 PB1 PF00564.19 KFM12589.1 - 0.076 12.6 0.1 0.19 11.3 0.1 1.7 1 0 0 1 1 1 0 PB1 domain APG12 PF04110.8 KFM12589.1 - 0.077 13.1 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like autophagy protein Apg12 ANF_receptor PF01094.23 KFM12590.1 - 2e-58 197.8 0.0 3e-58 197.2 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.21 KFM12590.1 - 6.1e-47 159.0 0.1 1e-46 158.3 0.1 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.4 KFM12590.1 - 1.6e-26 92.0 0.1 3.8e-26 90.8 0.1 1.7 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.15 KFM12590.1 - 2.3e-22 79.3 0.0 4.9e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.1 KFM12590.1 - 0.0071 15.7 0.0 0.019 14.3 0.0 1.7 1 1 0 1 1 1 1 Periplasmic binding protein TRAM_LAG1_CLN8 PF03798.11 KFM12591.1 - 0.00011 21.7 1.0 0.00011 21.7 0.7 1.4 2 0 0 2 2 2 1 TLC domain TRAM_LAG1_CLN8 PF03798.11 KFM12592.1 - 0.0002 20.9 0.1 0.0002 20.9 0.1 2.1 1 1 1 2 2 2 1 TLC domain DUF998 PF06197.8 KFM12592.1 - 0.012 14.9 0.5 0.015 14.6 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF998) CoxIIa PF08113.6 KFM12592.1 - 0.26 11.0 3.0 1.5 8.6 0.3 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IIa family TMEM190 PF15431.1 KFM12592.1 - 1.2 9.0 4.1 0.55 10.1 0.9 1.7 2 0 0 2 2 2 0 Transmembrane protein 190 Pou PF00157.12 KFM12593.1 - 3.1e-39 132.4 0.1 6e-39 131.5 0.1 1.5 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.24 KFM12593.1 - 1.5e-18 66.1 3.3 3.9e-18 64.8 2.3 1.8 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFM12593.1 - 0.0058 16.3 0.1 0.019 14.6 0.0 1.9 2 0 0 2 2 2 1 Homeobox KN domain HTH_3 PF01381.17 KFM12593.1 - 0.12 12.2 0.2 1.1 9.1 0.0 2.3 2 1 0 2 2 2 0 Helix-turn-helix OAF PF14941.1 KFM12594.1 - 2.3e-112 373.9 3.4 2.6e-112 373.8 2.4 1.0 1 0 0 1 1 1 1 Transcriptional regulator, Out at first BRICHOS PF04089.9 KFM12594.1 - 0.049 13.4 0.1 0.11 12.3 0.0 1.5 2 0 0 2 2 2 0 BRICHOS domain C2-set_2 PF08205.7 KFM12595.1 - 1.5e-19 69.6 0.5 6.1e-18 64.5 0.0 2.8 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain ig PF00047.20 KFM12595.1 - 1.2e-16 60.5 2.2 2.7e-08 33.8 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.1 KFM12595.1 - 1.9e-16 59.9 4.6 3.7e-07 30.1 0.0 3.4 3 1 0 3 3 3 2 Immunoglobulin domain V-set PF07686.12 KFM12595.1 - 2.3e-12 46.8 1.4 1.1e-11 44.6 0.0 2.5 3 1 0 3 3 3 1 Immunoglobulin V-set domain Ig_3 PF13927.1 KFM12595.1 - 3.8e-12 46.5 6.9 0.00044 20.6 0.2 3.9 3 1 0 3 3 3 3 Immunoglobulin domain I-set PF07679.11 KFM12595.1 - 5.4e-08 32.5 0.1 0.00068 19.4 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin I-set domain Herpes_gE PF02480.11 KFM12595.1 - 0.012 13.8 0.0 0.015 13.6 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Protocadherin PF08374.6 KFM12596.1 - 0.0019 17.8 0.0 0.0023 17.5 0.0 1.1 1 0 0 1 1 1 1 Protocadherin EphA2_TM PF14575.1 KFM12596.1 - 0.0083 16.5 0.2 0.012 15.9 0.1 1.5 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.15 KFM12596.1 - 0.064 12.9 0.6 0.11 12.2 0.4 1.3 1 0 0 1 1 1 0 Syndecan domain Shisa PF13908.1 KFM12596.1 - 0.074 13.2 0.1 0.096 12.8 0.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Tmemb_cc2 PF10267.4 KFM12597.1 - 1.9e-171 569.9 13.4 2.2e-171 569.7 9.3 1.0 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Rootletin PF15035.1 KFM12597.1 - 0.0026 17.7 1.9 0.0026 17.7 1.3 3.7 3 1 1 4 4 4 2 Ciliary rootlet component, centrosome cohesion DUF2407_C PF13373.1 KFM12597.1 - 0.021 14.7 0.2 0.021 14.7 0.1 2.0 2 0 0 2 2 2 0 DUF2407 C-terminal domain Orbi_NS3 PF01616.11 KFM12597.1 - 0.035 13.0 2.7 0.088 11.7 1.8 1.6 1 0 0 1 1 1 0 Orbivirus NS3 COG2 PF06148.6 KFM12597.1 - 0.13 12.1 17.1 0.035 13.9 3.0 3.2 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 TMCO5 PF14992.1 KFM12597.1 - 0.36 9.9 20.9 0.89 8.6 4.8 2.4 2 0 0 2 2 2 0 TMCO5 family Phage_GPO PF05929.6 KFM12597.1 - 1.3 8.1 20.9 0.019 14.2 1.5 2.9 3 1 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4618 PF15397.1 KFM12597.1 - 1.3 8.2 22.5 0.23 10.7 5.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) CorA PF01544.13 KFM12597.1 - 1.9 7.4 14.3 2 7.3 0.7 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.7 KFM12597.1 - 9.3 6.0 12.2 3.8 7.3 2.6 3.2 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus NDUFA12 PF05071.11 KFM12598.1 - 6e-30 103.7 2.6 7.3e-30 103.5 1.8 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 WHIM2 PF15613.1 KFM12598.1 - 0.21 11.5 1.4 0.55 10.2 0.0 2.1 2 1 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 2 Hormone_recep PF00104.25 KFM12599.1 - 5.1e-33 113.9 0.6 9e-33 113.1 0.4 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFM12599.1 - 1.7e-31 108.2 15.5 3.9e-31 107.0 10.8 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) DUF2318 PF10080.4 KFM12599.1 - 2.1 8.1 9.1 0.044 13.5 0.5 2.2 1 1 0 2 2 2 0 Predicted membrane protein (DUF2318) RhoGEF PF00621.15 KFM12600.1 - 1.3e-39 135.8 1.9 1.3e-39 135.8 1.3 2.6 2 0 0 2 2 2 1 RhoGEF domain FYVE PF01363.16 KFM12600.1 - 1.3e-20 73.0 10.2 3.2e-20 71.7 7.1 1.7 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 KFM12600.1 - 2.5e-17 62.9 1.9 5.6e-09 36.1 0.0 3.5 3 0 0 3 3 3 2 PH domain PH_11 PF15413.1 KFM12600.1 - 7.3e-07 29.4 1.3 0.052 13.7 0.0 3.3 3 0 0 3 3 3 2 Pleckstrin homology domain FYVE_2 PF02318.11 KFM12600.1 - 0.0039 17.0 10.5 0.0039 17.0 7.3 2.1 2 0 0 2 2 2 1 FYVE-type zinc finger Peptidase_M24 PF00557.19 KFM12602.1 - 1e-48 165.6 0.0 1.4e-48 165.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 UCH PF00443.24 KFM12603.1 - 1.4e-63 214.4 1.4 2.8e-63 213.5 1.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KFM12603.1 - 1e-20 73.5 8.9 1e-20 73.5 6.1 3.1 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 KFM12603.1 - 2.7e-18 66.4 3.5 3.2e-13 49.7 0.2 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ArfGap PF01412.13 KFM12603.1 - 9.5 6.0 12.8 0.091 12.5 2.5 2.4 3 0 0 3 3 3 0 Putative GTPase activating protein for Arf Amidohydro_4 PF13147.1 KFM12604.1 - 1.1e-22 81.3 0.3 1.2e-20 74.7 0.2 2.4 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KFM12604.1 - 3.6e-14 53.1 0.9 1.1e-08 35.0 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 KFM12604.1 - 5.1e-13 49.0 0.8 5.2e-09 35.8 0.5 2.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KFM12604.1 - 1e-11 44.4 0.0 2.3e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Lyase_aromatic PF00221.14 KFM12605.1 - 1e-188 627.6 0.0 1.2e-188 627.3 0.0 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase DUF3534 PF12053.3 KFM12605.1 - 0.02 14.7 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3534) Peptidase_M1 PF01433.15 KFM12606.1 - 1.1e-62 212.3 0.0 1.4e-62 212.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 KFM12606.1 - 1.5e-46 157.5 0.0 3e-46 156.5 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 KFM12606.1 - 1.1e-16 61.0 0.0 1.8e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 KFM12606.1 - 0.29 11.1 1.9 1.4 8.9 1.3 2.0 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Ets PF00178.17 KFM12607.1 - 9.2e-38 128.2 3.5 1.4e-37 127.6 2.4 1.3 1 0 0 1 1 1 1 Ets-domain Pkinase PF00069.20 KFM12608.1 - 3.3e-74 249.3 0.0 6.7e-74 248.3 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM12608.1 - 4.7e-35 120.9 0.0 1e-34 119.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM12608.1 - 2.5e-07 29.9 0.0 4.3e-07 29.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFM12608.1 - 0.0014 17.7 0.1 0.0039 16.2 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KFM12608.1 - 0.033 13.5 0.1 0.067 12.5 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.6 KFM12608.1 - 0.039 12.7 0.1 0.074 11.8 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 KFM12608.1 - 0.07 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family TPR_12 PF13424.1 KFM12611.1 - 0.0024 17.7 7.4 0.62 10.0 0.6 3.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFM12611.1 - 0.014 15.0 1.7 3.2 7.7 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 KFM12611.1 - 0.064 12.9 7.7 2.5 7.8 0.8 3.3 2 1 1 3 3 3 0 TPR repeat TPR_2 PF07719.12 KFM12611.1 - 0.094 12.6 5.5 1.5 8.8 0.4 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat LEA_1 PF03760.10 KFM12612.1 - 0.57 10.3 2.5 0.45 10.7 0.5 1.7 2 0 0 2 2 2 0 Late embryogenesis abundant (LEA) group 1 IL17_R_N PF15037.1 KFM12614.1 - 5.5e-47 160.6 8.6 5.6e-47 160.6 5.3 1.3 1 1 0 1 1 1 1 Interleukin-17 receptor extracellular region KASH PF10541.4 KFM12615.1 - 0.54 10.1 4.9 7 6.5 0.0 2.6 2 0 0 2 2 2 0 Nuclear envelope localisation domain AAA_12 PF13087.1 KFM12616.1 - 9.4e-46 155.7 0.0 1.7e-45 154.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KFM12616.1 - 7.4e-37 127.1 0.0 3.4e-18 66.1 0.0 2.3 1 1 1 2 2 2 2 AAA domain S1-like PF14444.1 KFM12616.1 - 2.3e-11 43.2 0.6 0.00046 19.8 0.2 3.7 3 0 0 3 3 3 2 S1-like AAA_30 PF13604.1 KFM12616.1 - 3.3e-11 43.1 0.0 1.5e-10 40.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFM12616.1 - 9.1e-09 34.9 0.0 2.5e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain DEAD PF00270.24 KFM12616.1 - 0.00072 19.0 0.0 0.002 17.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KFM12616.1 - 0.0037 17.1 0.0 0.011 15.5 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.1 KFM12616.1 - 0.0043 17.1 0.0 0.0093 16.0 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD_C PF13361.1 KFM12616.1 - 0.0044 16.5 0.0 0.49 9.7 0.0 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 KFM12616.1 - 0.0053 16.8 0.0 0.019 15.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain PhoH PF02562.11 KFM12616.1 - 0.015 14.5 0.0 2.7 7.1 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein UvrD-helicase PF00580.16 KFM12616.1 - 0.022 14.0 0.0 2.1 7.5 0.0 2.3 1 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA PF00004.24 KFM12616.1 - 0.047 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Innexin PF00876.13 KFM12618.1 - 8.9e-08 31.6 4.9 6.7e-07 28.7 3.4 2.2 1 1 0 1 1 1 1 Innexin TraB PF01963.12 KFM12619.1 - 3.3e-46 157.8 0.0 5.4e-46 157.1 0.0 1.3 1 1 0 1 1 1 1 TraB family RRM_3 PF08777.6 KFM12619.1 - 0.082 12.7 0.2 0.58 10.0 0.0 2.4 3 0 0 3 3 3 0 RNA binding motif Glyco_tran_WecB PF03808.8 KFM12619.1 - 0.11 11.8 0.1 0.61 9.4 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family UPF0061 PF02696.9 KFM12620.1 - 3.8e-109 365.1 0.4 1.2e-100 337.1 0.0 2.1 1 1 1 2 2 2 2 Uncharacterized ACR, YdiU/UPF0061 family XPC-binding PF09280.6 KFM12620.1 - 0.04 13.3 1.3 0.3 10.5 0.4 2.6 3 0 0 3 3 3 0 XPC-binding domain DUF896 PF05979.7 KFM12620.1 - 1.9 8.1 6.1 1.2 8.7 0.6 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) Spc97_Spc98 PF04130.8 KFM12621.1 - 8.2e-125 417.1 0.5 1.8e-124 416.0 0.3 1.5 1 1 0 1 1 1 1 Spc97 / Spc98 family DUF4573 PF15140.1 KFM12621.1 - 0.00088 18.9 0.0 0.002 17.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4573) Fz PF01392.17 KFM12622.1 - 3e-29 101.7 7.4 3e-29 101.7 5.1 2.0 3 0 0 3 3 3 1 Fz domain Pkinase PF00069.20 KFM12623.1 - 9.4e-67 224.8 0.1 1.2e-66 224.5 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM12623.1 - 2.8e-27 95.4 0.1 3.8e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM12623.1 - 0.00021 20.3 0.1 0.00084 18.3 0.0 2.0 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 KFM12623.1 - 0.0005 19.8 0.0 0.0011 18.7 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KFM12623.1 - 0.00073 18.9 0.0 0.0016 17.8 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KFM12623.1 - 0.0088 15.1 0.2 0.036 13.1 0.1 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KFM12624.1 - 7.8e-64 215.3 0.1 9.3e-64 215.0 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM12624.1 - 1.5e-26 93.0 0.1 1.8e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFM12624.1 - 1.1e-05 24.5 0.1 1.6e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFM12624.1 - 0.0021 17.8 0.0 0.011 15.4 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KFM12624.1 - 0.0029 16.9 0.0 0.0053 16.1 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 KFM12624.1 - 0.012 14.5 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF3890 PF13029.1 KFM12624.1 - 0.15 12.1 1.6 0.22 11.6 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3890) Plexin_cytopl PF08337.7 KFM12625.1 - 1.3e-246 819.1 9.1 1.8e-246 818.6 6.3 1.2 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain Sema PF01403.14 KFM12625.1 - 8e-36 123.4 10.3 8.7e-36 123.3 3.3 2.2 1 1 1 2 2 2 2 Sema domain TIG PF01833.19 KFM12625.1 - 1.9e-34 117.4 13.4 5.1e-11 42.4 1.3 6.0 6 0 0 6 6 6 4 IPT/TIG domain PSI PF01437.20 KFM12625.1 - 1.3e-13 50.8 53.9 1.3e-10 41.2 11.5 3.6 3 0 0 3 3 3 3 Plexin repeat RasGAP PF00616.14 KFM12625.1 - 9.7e-06 25.3 0.0 0.00028 20.6 0.0 2.9 3 1 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase zf-C2H2_4 PF13894.1 KFM12627.1 - 1.8e-17 62.3 52.9 0.00058 20.0 0.4 7.6 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2 PF00096.21 KFM12627.1 - 3.2e-15 55.4 60.3 0.0036 17.5 3.4 7.7 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KFM12627.1 - 1.1e-09 37.7 5.6 1.3e-08 34.4 0.1 7.1 7 1 0 7 7 7 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KFM12627.1 - 2e-06 27.8 34.6 0.018 15.1 1.5 7.1 6 1 1 7 7 7 3 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 KFM12627.1 - 1.4e-05 25.0 27.3 0.0013 18.8 0.9 5.3 5 0 0 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 KFM12627.1 - 7.4e-05 22.8 34.0 0.001 19.1 0.4 6.8 7 0 0 7 7 6 2 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 KFM12627.1 - 8.3e-05 22.5 0.2 8.3e-05 22.5 0.2 7.1 7 0 0 7 7 7 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 KFM12627.1 - 0.00044 20.2 1.0 0.00044 20.2 0.7 7.3 9 0 0 9 9 9 3 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 KFM12627.1 - 0.022 15.0 0.5 0.022 15.0 0.3 10.8 12 1 0 12 12 10 0 Zinc-finger double domain CpXC PF14353.1 KFM12627.1 - 0.3 11.0 0.0 0.3 11.0 0.0 4.4 5 1 1 6 6 5 0 CpXC protein DUF629 PF04780.7 KFM12627.1 - 4.6 5.6 23.0 0.42 9.0 0.6 5.5 5 1 1 6 6 6 0 Protein of unknown function (DUF629) Vps39_2 PF10367.4 KFM12627.1 - 5.8 7.1 20.5 0.088 12.9 2.9 4.2 4 0 0 4 4 4 0 Vacuolar sorting protein 39 domain 2 ANF_receptor PF01094.23 KFM12628.1 - 9.6e-16 57.4 0.0 1.1e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.17 KFM12629.1 - 2.2e-85 285.8 16.1 2.9e-85 285.4 11.1 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.23 KFM12629.1 - 5.8e-43 147.0 0.0 7.5e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.9 KFM12629.1 - 2.4e-14 52.8 10.9 4.7e-14 51.8 7.6 1.5 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Arf PF00025.16 KFM12631.1 - 3.3e-36 124.1 0.0 3.7e-36 123.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KFM12631.1 - 1.3e-11 44.1 0.0 1.5e-11 43.9 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KFM12631.1 - 6.9e-06 24.9 0.0 9.4e-06 24.5 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Miro PF08477.8 KFM12631.1 - 1.9e-05 25.1 0.0 2.5e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 KFM12631.1 - 6.2e-05 22.2 0.0 6.4e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFM12631.1 - 0.005 16.2 0.0 0.0055 16.1 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Glyco_hydro_56 PF01630.13 KFM12632.1 - 5.1e-139 462.6 0.2 6e-139 462.4 0.2 1.0 1 0 0 1 1 1 1 Hyaluronidase DUF1830 PF08865.6 KFM12633.1 - 0.083 12.5 0.0 0.099 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1830) Glyco_hydro_56 PF01630.13 KFM12634.1 - 4.8e-136 452.8 1.5 5.7e-136 452.6 1.0 1.0 1 0 0 1 1 1 1 Hyaluronidase EGF PF00008.22 KFM12634.1 - 0.0016 18.3 1.7 0.096 12.6 0.0 2.5 2 0 0 2 2 2 1 EGF-like domain hEGF PF12661.2 KFM12634.1 - 0.036 14.1 3.6 0.036 14.1 2.5 1.9 2 0 0 2 2 2 0 Human growth factor-like EGF TerD PF02342.13 KFM12634.1 - 0.048 12.9 0.0 0.078 12.2 0.0 1.2 1 0 0 1 1 1 0 TerD domain EGF_2 PF07974.8 KFM12634.1 - 2.9 8.1 10.0 1 9.6 1.5 2.5 2 0 0 2 2 2 0 EGF-like domain WH1 PF00568.18 KFM12635.1 - 1.4e-36 124.5 0.1 2e-36 124.0 0.0 1.3 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 KFM12635.1 - 5.4e-17 60.7 1.7 1e-07 31.3 0.1 2.6 2 0 0 2 2 2 2 WH2 motif PBD PF00786.23 KFM12635.1 - 8.5e-17 61.3 0.0 2.4e-16 59.8 0.0 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain PQQ PF01011.16 KFM12635.1 - 0.06 12.9 0.0 0.3 10.6 0.0 2.2 1 0 0 1 1 1 0 PQQ enzyme repeat Ank_2 PF12796.2 KFM12636.1 - 1.4e-87 288.1 23.9 9e-17 61.1 0.6 5.8 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 KFM12636.1 - 1.1e-47 157.5 16.4 1.5e-05 24.5 0.4 11.3 11 0 0 11 11 11 9 Ankyrin repeat Ank_4 PF13637.1 KFM12636.1 - 1.5e-41 140.0 6.0 1.4e-08 34.9 0.0 7.6 6 2 3 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM12636.1 - 5.6e-41 134.4 7.6 0.001 19.1 0.0 11.1 11 0 0 11 11 11 9 Ankyrin repeat Ank_5 PF13857.1 KFM12636.1 - 2.4e-32 110.1 15.4 6.3e-08 32.6 0.2 9.2 2 1 9 11 11 11 9 Ankyrin repeats (many copies) SOCS_box PF07525.11 KFM12636.1 - 3e-10 39.7 7.7 6.4e-10 38.7 5.4 1.6 1 0 0 1 1 1 1 SOCS box ETC_C1_NDUFA5 PF04716.9 KFM12637.1 - 2e-23 81.6 0.3 3.4e-23 80.9 0.2 1.4 1 0 0 1 1 1 1 ETC complex I subunit conserved region ATP-synt_S1 PF05827.7 KFM12639.1 - 6.1e-36 124.1 0.9 7e-36 123.9 0.6 1.0 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Lamp PF01299.12 KFM12639.1 - 4.4e-06 26.0 0.3 7.4e-06 25.3 0.2 1.3 1 0 0 1 1 1 1 Lysosome-associated membrane glycoprotein (Lamp) Na_sulph_symp PF00939.14 KFM12640.1 - 7.4e-93 311.9 31.9 9.9e-93 311.5 22.1 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 KFM12640.1 - 2.4e-08 32.9 34.8 0.0024 16.5 0.0 3.2 2 1 1 3 3 3 3 Citrate transporter DUF1041 PF06292.12 KFM12641.1 - 1.8e-29 102.0 2.8 4.9e-29 100.6 1.9 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1041) PH PF00169.24 KFM12641.1 - 2.5e-06 27.6 0.0 5.6e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KFM12641.1 - 0.053 13.7 2.6 0.13 12.5 1.2 2.2 1 1 1 2 2 2 0 Pleckstrin homology domain Y_phosphatase PF00102.22 KFM12642.1 - 7e-149 493.5 5.9 6.1e-89 297.3 0.9 2.6 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Carb_anhydrase PF00194.16 KFM12642.1 - 4.4e-56 189.6 0.0 7.9e-56 188.8 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase fn3 PF00041.16 KFM12642.1 - 2.7e-11 43.4 0.1 9.4e-11 41.6 0.1 2.1 1 0 0 1 1 1 1 Fibronectin type III domain DSPc PF00782.15 KFM12642.1 - 0.00046 19.7 0.1 0.018 14.5 0.0 3.2 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFM12642.1 - 0.004 17.4 0.1 0.031 14.5 0.0 2.5 2 0 0 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KFM12642.1 - 0.029 14.4 0.1 0.17 11.8 0.0 2.3 2 0 0 2 2 2 0 Inositol hexakisphosphate PC-Esterase PF13839.1 KFM12644.1 - 1.5e-27 97.0 0.9 1.5e-27 97.0 0.6 2.8 3 2 0 3 3 3 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Cadherin-like PF12733.2 KFM12644.1 - 6.7e-09 35.9 0.0 1.4e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Cadherin-like beta sandwich domain Terminase_GpA PF05876.7 KFM12644.1 - 0.055 11.8 2.6 0.087 11.1 1.8 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) ING PF12998.2 KFM12645.1 - 2.1e-15 56.9 3.6 2.1e-15 56.9 2.5 2.1 3 0 0 3 3 3 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 KFM12645.1 - 9.1e-11 41.2 7.6 1.7e-10 40.3 5.3 1.5 1 0 0 1 1 1 1 PHD-finger Myosin_tail_1 PF01576.14 KFM12645.1 - 0.015 13.0 3.4 0.021 12.5 2.4 1.3 1 0 0 1 1 1 0 Myosin tail zf-RING-like PF08746.6 KFM12645.1 - 0.22 11.5 6.1 0.43 10.6 4.2 1.5 1 0 0 1 1 1 0 RING-like domain Tetraspannin PF00335.15 KFM12646.1 - 9.2e-33 113.3 8.7 1.2e-32 112.9 6.1 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF3399 PF11879.3 KFM12647.1 - 1.7e-44 150.3 9.2 1.7e-44 150.3 6.4 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3399) Ion_trans_2 PF07885.11 KFM12647.1 - 0.0012 18.5 0.1 0.0018 17.9 0.1 1.3 1 0 0 1 1 1 1 Ion channel BTB_2 PF02214.17 KFM12648.1 - 4.9e-28 97.1 0.1 1.5e-27 95.6 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans PF00520.26 KFM12648.1 - 1.9e-22 79.5 10.5 1.9e-22 79.5 7.3 1.7 2 0 0 2 2 2 1 Ion transport protein Shal-type PF11601.3 KFM12648.1 - 5.2e-14 51.4 16.5 8.8e-14 50.7 11.4 1.4 1 0 0 1 1 1 1 Shal-type voltage-gated potassium channels PKD_channel PF08016.7 KFM12648.1 - 0.0019 16.6 4.0 0.0019 16.6 2.8 1.5 2 0 0 2 2 2 1 Polycystin cation channel Ion_trans_2 PF07885.11 KFM12648.1 - 0.014 15.1 4.0 0.014 15.1 2.8 2.7 3 0 0 3 3 3 0 Ion channel IlvGEDA_leader PF08046.6 KFM12648.1 - 6.7 5.9 5.7 0.45 9.6 0.2 1.9 2 0 0 2 2 2 0 IlvGEDA operon leader peptide Ank PF00023.25 KFM12650.1 - 3.7e-37 124.3 7.8 6.2e-09 35.2 0.2 4.0 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 KFM12650.1 - 3.3e-33 113.8 4.8 2.2e-16 59.9 0.2 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFM12650.1 - 1.1e-27 95.4 5.8 1.6e-09 37.6 0.4 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM12650.1 - 4.6e-27 91.3 2.4 1.5e-06 27.8 0.1 4.0 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 KFM12650.1 - 2.3e-25 88.4 1.7 3e-10 40.3 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) DUF3447 PF11929.3 KFM12650.1 - 0.04 13.7 0.0 0.9 9.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) RVT_1 PF00078.22 KFM12651.1 - 0.05 12.9 0.0 0.071 12.4 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Ank PF00023.25 KFM12652.1 - 5.4e-40 133.2 6.0 1.3e-09 37.3 0.0 4.0 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 KFM12652.1 - 7.3e-35 119.1 5.1 3.5e-17 62.5 0.7 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFM12652.1 - 1.6e-28 98.5 3.9 1.4e-08 34.9 0.1 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM12652.1 - 5.7e-26 87.9 4.2 6.5e-07 28.9 0.1 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 KFM12652.1 - 2.5e-25 87.9 7.0 4.2e-09 36.3 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Mic1 PF07035.7 KFM12652.1 - 0.0074 15.6 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Colon cancer-associated protein Mic1-like DUF3447 PF11929.3 KFM12652.1 - 0.015 15.0 0.0 0.8 9.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) Shigella_OspC PF06128.6 KFM12652.1 - 0.1 12.0 0.1 2.9 7.2 0.0 2.3 2 1 0 2 2 2 0 Shigella flexneri OspC protein CCDC144C PF14915.1 KFM12653.1 - 2.1e-123 411.1 61.8 2.1e-123 411.1 42.8 5.5 3 2 2 5 5 5 1 CCDC144C protein coiled-coil region DUF3496 PF12001.3 KFM12653.1 - 8.8e-18 64.5 1.0 8.8e-18 64.5 0.7 9.0 6 3 3 9 9 9 1 Domain of unknown function (DUF3496) LSM PF01423.17 KFM12654.1 - 1.2e-14 53.5 0.6 1.5e-14 53.2 0.4 1.1 1 0 0 1 1 1 1 LSM domain ABC_membrane PF00664.18 KFM12655.1 - 2.2e-97 325.8 40.1 8.1e-50 169.7 12.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region CFTR_R PF14396.1 KFM12655.1 - 5e-96 320.1 2.9 5e-96 320.1 2.0 1.8 2 0 0 2 2 2 1 Cystic fibrosis TM conductance regulator (CFTR), regulator domain ABC_tran PF00005.22 KFM12655.1 - 1.1e-54 184.4 0.0 1.2e-30 106.6 0.0 3.0 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KFM12655.1 - 5e-07 29.9 2.5 0.01 15.8 0.0 4.5 4 1 0 4 4 4 1 AAA domain SMC_N PF02463.14 KFM12655.1 - 1.4e-06 27.6 0.0 0.017 14.3 0.0 3.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KFM12655.1 - 1.5e-06 27.5 0.9 0.0017 17.8 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 KFM12655.1 - 3.5e-06 26.1 0.0 0.024 13.5 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.1 KFM12655.1 - 7.2e-06 26.1 0.2 0.012 15.6 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.1 KFM12655.1 - 6.4e-05 22.1 1.8 0.00038 19.6 0.0 3.1 5 0 0 5 5 5 1 AAA ATPase domain DUF258 PF03193.11 KFM12655.1 - 0.00013 21.1 0.4 0.12 11.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 DUF87 PF01935.12 KFM12655.1 - 0.00033 20.5 0.8 0.24 11.1 0.1 2.7 2 0 0 2 2 2 2 Domain of unknown function DUF87 Miro PF08477.8 KFM12655.1 - 0.00036 20.9 0.4 1.2 9.6 0.0 3.1 3 0 0 3 3 2 2 Miro-like protein NACHT PF05729.7 KFM12655.1 - 0.0019 17.8 0.5 1.6 8.3 0.0 2.8 2 0 0 2 2 2 2 NACHT domain NTPase_1 PF03266.10 KFM12655.1 - 0.0028 17.3 0.3 0.12 12.1 0.0 2.8 3 0 0 3 3 2 1 NTPase ArgK PF03308.11 KFM12655.1 - 0.004 15.9 0.1 0.077 11.7 0.0 2.4 2 0 0 2 2 2 1 ArgK protein AAA_17 PF13207.1 KFM12655.1 - 0.0046 17.7 0.0 2.8 8.7 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.1 KFM12655.1 - 0.0047 16.5 0.0 0.55 9.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KFM12655.1 - 0.0049 16.9 0.2 4 7.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 KFM12655.1 - 0.0078 15.6 0.1 2.9 7.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 KFM12655.1 - 0.011 16.0 17.6 0.56 10.4 3.3 4.9 4 1 0 4 4 4 0 AAA domain Zeta_toxin PF06414.7 KFM12655.1 - 0.013 14.5 0.2 0.59 9.1 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin MMR_HSR1 PF01926.18 KFM12655.1 - 0.017 15.1 0.3 0.64 9.9 0.2 3.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase UPF0079 PF02367.12 KFM12655.1 - 0.025 14.2 0.3 1.2 8.8 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 cobW PF02492.14 KFM12655.1 - 0.03 13.7 1.4 5.2 6.4 0.1 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 KFM12655.1 - 0.059 13.6 0.0 5.5 7.2 0.0 3.0 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KFM12655.1 - 0.068 12.6 0.3 3.6 6.9 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_19 PF13245.1 KFM12655.1 - 0.07 12.8 0.6 27 4.5 0.0 3.4 3 0 0 3 3 3 0 Part of AAA domain ATP-synt_ab PF00006.20 KFM12655.1 - 0.13 11.6 0.3 11 5.4 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Ank_2 PF12796.2 KFM12656.1 - 1.1e-32 112.2 5.0 2.4e-20 72.6 0.2 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFM12656.1 - 1.3e-29 100.4 4.1 3.4e-08 32.9 0.0 5.2 5 1 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 KFM12656.1 - 2.5e-24 84.7 3.3 9.6e-11 41.5 0.0 4.3 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM12656.1 - 1.5e-21 74.3 2.9 5e-05 23.1 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 KFM12656.1 - 1.5e-18 66.7 2.0 2.8e-12 46.8 0.0 3.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) SAM_1 PF00536.25 KFM12656.1 - 1.1e-09 38.2 0.3 2.2e-09 37.3 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFM12656.1 - 5.3e-09 35.7 0.3 1.2e-08 34.6 0.2 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) wnt PF00110.14 KFM12657.1 - 1.8e-101 339.4 25.1 2e-101 339.2 17.4 1.0 1 0 0 1 1 1 1 wnt family ST7 PF04184.7 KFM12658.1 - 2e-277 920.7 2.1 2.3e-277 920.5 1.5 1.0 1 0 0 1 1 1 1 ST7 protein TPR_6 PF13174.1 KFM12658.1 - 0.00015 21.9 0.5 0.00058 20.1 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Clathrin PF00637.15 KFM12658.1 - 0.041 13.4 0.1 0.094 12.3 0.1 1.5 1 0 0 1 1 1 0 Region in Clathrin and VPS TPR_1 PF00515.23 KFM12658.1 - 0.13 11.9 2.8 20 5.0 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 KFM12658.1 - 0.13 12.1 5.7 2.7 8.1 0.0 4.4 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFM12658.1 - 3.3 8.1 7.3 1.3 9.3 0.3 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat F-actin_cap_A PF01267.12 KFM12659.1 - 5.4e-103 343.7 3.4 6e-103 343.6 2.4 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit F_actin_cap_B PF01115.12 KFM12659.1 - 0.044 12.9 1.3 0.088 11.9 0.9 1.5 1 1 0 1 1 1 0 F-actin capping protein, beta subunit Sema PF01403.14 KFM12660.1 - 2.8e-105 352.3 5.4 4.5e-105 351.6 3.7 1.2 1 0 0 1 1 1 1 Sema domain Pkinase_Tyr PF07714.12 KFM12660.1 - 8.3e-94 313.4 0.0 1.2e-93 312.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM12660.1 - 3.5e-43 147.6 0.0 6.5e-43 146.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain TIG PF01833.19 KFM12660.1 - 1.1e-33 115.0 11.3 2.9e-14 52.8 0.1 5.1 4 0 0 4 4 4 4 IPT/TIG domain PSI PF01437.20 KFM12660.1 - 7.6e-08 32.3 15.9 3.2e-07 30.3 11.0 2.2 1 0 0 1 1 1 1 Plexin repeat Kinase-like PF14531.1 KFM12660.1 - 2.5e-05 23.3 0.0 5e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Caveolin PF01146.12 KFM12661.1 - 7.5e-57 191.0 5.0 8.2e-57 190.9 3.5 1.0 1 0 0 1 1 1 1 Caveolin Caveolin PF01146.12 KFM12662.1 - 5.4e-53 178.5 6.8 5.9e-53 178.4 4.7 1.0 1 0 0 1 1 1 1 Caveolin DUF4481 PF14800.1 KFM12662.1 - 0.64 8.8 4.7 0.64 8.8 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) DUF2512 PF10710.4 KFM12662.1 - 1.9 7.9 6.6 1.7 8.0 3.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2512) DUF1700 PF08006.6 KFM12662.1 - 4.7 6.4 6.9 5.7 6.2 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) PET PF06297.9 KFM12663.1 - 9.9e-43 144.1 1.4 1.7e-42 143.4 1.0 1.4 1 0 0 1 1 1 1 PET Domain LIM PF00412.17 KFM12663.1 - 1.9e-27 95.0 60.7 1.2e-13 50.9 7.3 4.7 4 2 1 5 5 5 3 LIM domain Mod_r PF07200.8 KFM12663.1 - 0.13 12.1 0.5 0.21 11.4 0.3 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF3371 PF11851.3 KFM12664.1 - 8.9e-39 133.1 4.4 8.9e-39 133.1 3.0 3.6 4 1 0 4 4 4 1 Domain of unknown function (DUF3371) HLH PF00010.21 KFM12664.1 - 1.5e-15 56.6 0.4 3.3e-15 55.5 0.3 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain UPF0449 PF15136.1 KFM12664.1 - 5.3 7.3 7.4 9.5 6.5 1.6 2.8 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 MDFI PF15316.1 KFM12665.1 - 2.5e-75 252.2 40.3 3.9e-75 251.6 27.9 1.3 1 0 0 1 1 1 1 MyoD family inhibitor Fork_head PF00250.13 KFM12666.1 - 2.3e-25 88.4 0.1 2.3e-25 88.4 0.1 2.0 2 0 0 2 2 2 1 Fork head domain Med15 PF09606.5 KFM12666.1 - 0.042 12.0 83.4 0.068 11.3 57.8 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Plasmodium_Vir PF05795.6 KFM12666.1 - 1.3 8.1 2.9 2.9 6.9 0.9 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Auxin_repressed PF05564.7 KFM12666.1 - 2.5 8.7 12.1 0.07 13.7 1.3 3.3 2 1 1 3 3 3 0 Dormancy/auxin associated protein DUF4557 PF15101.1 KFM12666.1 - 4.5 7.0 22.1 14 5.4 15.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Fork_head PF00250.13 KFM12668.1 - 1.1e-35 121.4 0.0 1.3e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 Fork head domain Linker_histone PF00538.14 KFM12668.1 - 0.082 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 linker histone H1 and H5 family BssC_TutF PF08201.6 KFM12668.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 BssC/TutF protein CBM_21 PF03370.8 KFM12669.1 - 1.5e-28 99.0 0.1 3.1e-28 98.0 0.1 1.6 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit DUF3321 PF11968.3 KFM12671.1 - 3.2e-08 33.4 0.6 1.4e-05 24.8 0.3 2.2 1 1 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 KFM12671.1 - 0.009 15.7 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_C14 PF00656.17 KFM12672.1 - 0.17 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Caspase domain Phtf-FEM1B_bdg PF12129.3 KFM12672.1 - 6.7 6.0 7.5 0.46 9.8 1.0 2.1 2 0 0 2 2 2 0 Male germ-cell putative homeodomain transcription factor DUF4577 PF15145.1 KFM12673.1 - 5.9e-40 136.1 0.4 6.7e-40 135.9 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4577) MscL PF01741.13 KFM12673.1 - 0.0034 17.5 0.1 0.0042 17.2 0.1 1.2 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL Tetraspannin PF00335.15 KFM12673.1 - 0.044 13.0 0.3 0.054 12.7 0.2 1.1 1 0 0 1 1 1 0 Tetraspanin family CCSMST1 PF15013.1 KFM12673.1 - 0.063 13.1 0.1 0.085 12.7 0.1 1.3 1 0 0 1 1 1 0 CCSMST1 family DUF948 PF06103.6 KFM12673.1 - 0.073 12.9 0.8 0.12 12.2 0.5 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF3328 PF11807.3 KFM12673.1 - 0.14 11.7 0.1 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) IFRD PF05004.8 KFM12674.1 - 3.7e-119 397.3 6.6 4.5e-119 397.1 4.6 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) IFRD_C PF04836.7 KFM12674.1 - 6.3e-27 93.5 0.5 6.3e-27 93.5 0.3 2.0 2 0 0 2 2 2 1 Interferon-related protein conserved region HEAT PF02985.17 KFM12674.1 - 0.046 13.7 0.3 9.5 6.6 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat zf-C2H2_2 PF12756.2 KFM12675.1 - 1.1e-43 147.4 24.3 8.7e-24 83.5 4.3 3.2 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KFM12675.1 - 5e-05 23.3 2.8 5e-05 23.3 1.9 4.2 5 0 0 5 5 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 KFM12675.1 - 0.00058 20.0 1.8 0.00058 20.0 1.2 5.4 5 1 0 5 5 5 2 Zinc finger, C2H2 type zf-BED PF02892.10 KFM12675.1 - 0.0035 17.0 1.4 0.0035 17.0 1.0 4.6 5 0 0 5 5 5 1 BED zinc finger zf-C2H2_4 PF13894.1 KFM12675.1 - 0.016 15.4 25.1 0.016 15.4 0.5 5.4 5 0 0 5 5 5 0 C2H2-type zinc finger YokU PF14122.1 KFM12675.1 - 0.017 14.8 0.1 0.12 12.1 0.0 2.5 2 0 0 2 2 2 0 YokU-like protein PyrI_C PF02748.10 KFM12675.1 - 0.034 13.5 0.2 0.034 13.5 0.1 4.0 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-met PF12874.2 KFM12675.1 - 0.06 13.5 1.2 0.06 13.5 0.9 3.6 3 1 0 3 3 3 0 Zinc-finger of C2H2 type BIR PF00653.16 KFM12675.1 - 0.079 13.3 11.9 0.98 9.8 0.1 5.2 5 0 0 5 5 5 0 Inhibitor of Apoptosis domain zf-H2C2_5 PF13909.1 KFM12675.1 - 0.18 12.1 0.2 0.18 12.1 0.1 4.8 5 0 0 5 5 5 0 C2H2-type zinc-finger domain zf-DBF PF07535.7 KFM12675.1 - 0.4 10.4 13.2 1.5 8.5 0.9 3.0 3 0 0 3 3 3 0 DBF zinc finger Ded_cyto PF06920.8 KFM12676.1 - 5.3e-51 172.4 0.5 9.5e-51 171.6 0.3 1.4 1 0 0 1 1 1 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 KFM12676.1 - 2.5e-49 167.4 0.0 1e-48 165.3 0.0 2.2 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins SH3_1 PF00018.23 KFM12676.1 - 0.00075 18.8 0.0 0.0017 17.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFM12676.1 - 0.00088 18.7 0.1 0.0027 17.1 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 KFM12676.1 - 0.0025 17.3 0.0 0.006 16.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain LRR_8 PF13855.1 KFM12677.1 - 4.1e-44 148.1 41.7 1.4e-12 47.1 3.7 6.9 2 1 5 8 8 8 7 Leucine rich repeat LRR_4 PF12799.2 KFM12677.1 - 3.2e-22 77.6 48.5 4.2e-05 23.0 0.3 7.7 3 2 5 9 9 9 9 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFM12677.1 - 8.1e-21 74.0 0.1 2e-08 33.9 0.0 3.5 1 1 2 3 3 3 3 Leucine rich repeats (6 copies) I-set PF07679.11 KFM12677.1 - 4.5e-13 48.8 0.0 1.8e-12 46.9 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin I-set domain LRR_1 PF00560.28 KFM12677.1 - 2.5e-09 35.8 35.4 1.8 8.9 0.0 11.8 11 1 1 12 12 11 4 Leucine Rich Repeat Ig_2 PF13895.1 KFM12677.1 - 1.8e-08 34.3 0.0 4e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFM12677.1 - 2.2e-08 34.4 0.2 6.6e-08 32.9 0.1 1.9 1 0 0 1 1 1 1 Immunoglobulin domain fn3 PF00041.16 KFM12677.1 - 3.1e-07 30.4 0.0 6.1e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III domain ig PF00047.20 KFM12677.1 - 3.8e-07 30.1 0.0 1.1e-06 28.6 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFM12677.1 - 4.3e-05 23.3 0.0 0.00011 22.0 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin V-set domain LRR_9 PF14580.1 KFM12677.1 - 0.00062 19.3 15.6 0.17 11.4 0.9 4.3 1 1 3 4 4 4 3 Leucine-rich repeat LRR_7 PF13504.1 KFM12677.1 - 0.0011 18.8 25.8 5.3 7.6 0.1 9.8 9 1 1 10 10 10 1 Leucine rich repeat LRRNT PF01462.13 KFM12677.1 - 0.014 14.8 0.9 0.014 14.8 0.7 3.1 4 0 0 4 4 3 0 Leucine rich repeat N-terminal domain LRRCT PF01463.19 KFM12677.1 - 0.048 13.9 0.0 0.15 12.3 0.0 2.0 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain UPF0102 PF02021.12 KFM12677.1 - 0.079 12.8 0.0 0.51 10.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0102 DnaJ PF00226.26 KFM12678.1 - 1.5e-28 98.3 2.8 2.3e-28 97.6 1.9 1.3 1 0 0 1 1 1 1 DnaJ domain THAP PF05485.7 KFM12679.1 - 7.8e-13 48.4 0.1 1.8e-12 47.2 0.1 1.6 1 0 0 1 1 1 1 THAP domain CENP-R PF06729.7 KFM12679.1 - 8 6.1 8.4 1.9 8.1 0.4 2.6 3 0 0 3 3 3 0 Kinetochore component, CENP-R 7tm_1 PF00001.16 KFM12680.1 - 1.2e-44 152.4 24.0 1.5e-44 152.1 16.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM12680.1 - 0.00095 18.3 25.3 0.0017 17.6 17.6 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Patatin PF01734.17 KFM12681.1 - 4.7e-24 85.4 0.0 4e-23 82.4 0.0 2.5 3 0 0 3 3 3 1 Patatin-like phospholipase COG2 PF06148.6 KFM12681.1 - 0.056 13.3 0.2 0.056 13.3 0.1 2.5 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 I-set PF07679.11 KFM12682.1 - 4.2e-71 234.8 0.0 5.7e-13 48.5 0.0 7.0 7 0 0 7 7 7 6 Immunoglobulin I-set domain fn3 PF00041.16 KFM12682.1 - 7e-63 208.7 16.0 2.6e-14 53.0 0.1 5.5 5 0 0 5 5 5 5 Fibronectin type III domain Ig_2 PF13895.1 KFM12682.1 - 3.4e-55 184.1 0.0 2.6e-09 37.0 0.0 6.5 6 0 0 6 6 6 6 Immunoglobulin domain Ig_3 PF13927.1 KFM12682.1 - 1.6e-49 166.2 0.4 7.5e-07 29.5 0.0 7.7 7 0 0 7 7 6 6 Immunoglobulin domain ig PF00047.20 KFM12682.1 - 5.2e-33 112.9 0.0 9.6e-07 28.8 0.0 8.0 7 0 0 7 7 7 5 Immunoglobulin domain Bravo_FIGEY PF13882.1 KFM12682.1 - 1.7e-32 112.1 9.3 3.9e-32 111.0 6.4 1.6 1 0 0 1 1 1 1 Bravo-like intracellular region V-set PF07686.12 KFM12682.1 - 3.8e-15 55.7 1.9 0.026 14.4 0.3 8.0 6 4 0 6 6 6 4 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM12682.1 - 1.1e-14 54.0 0.3 0.047 13.6 0.0 6.6 6 0 0 6 6 6 3 CD80-like C2-set immunoglobulin domain BiPBP_C PF06832.7 KFM12682.1 - 0.0012 18.7 0.0 3.7 7.5 0.0 3.5 2 0 0 2 2 2 2 Penicillin-Binding Protein C-terminus Family V-set_CD47 PF08204.6 KFM12682.1 - 0.0021 17.7 2.6 3.7 7.3 0.0 3.9 4 0 0 4 4 4 1 CD47 immunoglobulin-like domain Herpes_gE PF02480.11 KFM12682.1 - 0.015 13.5 0.0 4.4 5.4 0.0 3.6 3 1 0 4 4 4 0 Alphaherpesvirus glycoprotein E LST1 PF05083.8 KFM12682.1 - 0.25 11.3 0.4 1e+02 2.9 0.0 3.8 4 0 0 4 4 4 0 LST-1 protein I-set PF07679.11 KFM12683.1 - 1.1e-56 188.5 0.8 7.6e-12 44.9 0.0 8.5 7 1 0 7 7 7 6 Immunoglobulin I-set domain fn3 PF00041.16 KFM12683.1 - 4.6e-46 154.8 10.6 5.3e-17 61.7 0.8 4.7 4 0 0 4 4 4 4 Fibronectin type III domain Ig_2 PF13895.1 KFM12683.1 - 4.2e-43 145.3 0.0 2.6e-08 33.8 0.0 6.5 4 2 1 6 6 6 5 Immunoglobulin domain Ig_3 PF13927.1 KFM12683.1 - 2.3e-35 120.8 0.0 2e-05 24.9 0.0 7.3 8 0 0 8 8 7 5 Immunoglobulin domain V-set PF07686.12 KFM12683.1 - 4.3e-30 103.9 5.9 9.3e-06 25.5 0.0 8.6 6 4 3 9 9 9 5 Immunoglobulin V-set domain ig PF00047.20 KFM12683.1 - 3.2e-25 88.0 0.0 0.00011 22.2 0.0 7.1 6 1 0 6 6 6 5 Immunoglobulin domain Interfer-bind PF09294.5 KFM12683.1 - 1.4e-06 28.2 0.0 0.0017 18.3 0.1 3.7 4 0 0 4 4 4 1 Interferon-alpha/beta receptor, fibronectin type III C2-set_2 PF08205.7 KFM12683.1 - 3.3e-05 23.6 0.0 0.58 10.1 0.0 3.9 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Tissue_fac PF01108.12 KFM12683.1 - 0.0081 15.8 5.2 0.83 9.4 0.0 4.6 3 2 1 4 4 4 1 Tissue factor Sp38 PF07354.7 KFM12683.1 - 0.023 13.3 0.0 6.8 5.2 0.0 3.0 3 0 0 3 3 3 0 Zona-pellucida-binding protein (Sp38) Big_3_4 PF13754.1 KFM12683.1 - 0.028 14.7 0.6 0.9 9.9 0.0 3.4 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) Microtub_assoc PF07989.6 KFM12684.1 - 1.8e-28 98.1 8.1 1.8e-28 98.1 5.6 11.9 11 2 2 13 13 13 3 Microtubule associated Laminin_EGF PF00053.19 KFM12686.1 - 3.3e-42 142.1 95.3 4.8e-11 42.4 8.3 5.3 4 1 1 5 5 5 5 Laminin EGF-like (Domains III and V) cEGF PF12662.2 KFM12686.1 - 0.0053 16.3 1.6 0.0053 16.3 1.1 8.9 7 2 1 8 8 8 1 Complement Clr-like EGF-like TMEM154 PF15102.1 KFM12686.1 - 0.05 13.3 0.3 0.085 12.5 0.2 1.3 1 0 0 1 1 1 0 TMEM154 protein family ApoM PF11032.3 KFM12687.1 - 9.7e-15 54.6 0.0 1.2e-14 54.3 0.0 1.0 1 0 0 1 1 1 1 Apolipoprotein M (ApoM) Lipocalin PF00061.18 KFM12687.1 - 3.9e-08 33.3 0.0 6.9e-08 32.5 0.0 1.4 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Mito_carr PF00153.22 KFM12688.1 - 1e-74 246.3 2.7 2.9e-25 87.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 KFM12688.1 - 1.4e-14 53.9 2.2 3e-10 40.0 0.1 2.4 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KFM12688.1 - 5.4e-14 50.3 2.5 0.0012 18.0 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 KFM12688.1 - 1.9e-11 42.7 2.8 0.00033 20.2 0.1 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 KFM12688.1 - 4e-10 39.1 1.3 0.0012 18.4 0.1 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 KFM12688.1 - 7.6e-08 31.3 0.9 0.0074 15.5 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_10 PF14788.1 KFM12688.1 - 0.00035 20.1 0.5 2.1 8.0 0.0 3.5 2 1 1 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.4 KFM12688.1 - 0.00051 20.0 0.7 0.0013 18.7 0.5 1.6 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFM12688.1 - 0.076 12.7 2.9 0.75 9.5 0.1 2.4 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand UBN2 PF14223.1 KFM12688.1 - 0.098 12.4 0.7 1.1 9.0 0.1 2.3 1 1 1 2 2 2 0 gag-polypeptide of LTR copia-type NT-C2 PF10358.4 KFM12689.1 - 1.9e-30 105.2 0.3 6.2e-30 103.5 0.0 1.9 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins SMN PF06003.7 KFM12689.1 - 0.037 13.1 1.1 0.056 12.5 0.7 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) DPM2 PF07297.7 KFM12690.1 - 1.3e-21 76.6 0.4 1.4e-21 76.5 0.3 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) S1FA PF04689.8 KFM12690.1 - 0.0048 16.7 0.1 0.0056 16.5 0.1 1.1 1 0 0 1 1 1 1 DNA binding protein S1FA TMEM154 PF15102.1 KFM12690.1 - 0.033 13.8 0.2 0.037 13.7 0.2 1.0 1 0 0 1 1 1 0 TMEM154 protein family FixQ PF05545.6 KFM12690.1 - 0.05 13.2 0.3 0.075 12.6 0.2 1.3 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Glyco_transf_29 PF00777.13 KFM12691.1 - 1.4e-29 103.0 0.0 1.7e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Mur_ligase_M PF08245.7 KFM12692.1 - 0.0041 17.1 0.0 0.023 14.7 0.0 1.9 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 KFM12692.1 - 0.019 15.0 0.0 0.042 13.8 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Pkinase PF00069.20 KFM12693.1 - 1e-64 218.2 0.0 1.2e-64 218.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM12693.1 - 1.5e-28 99.6 0.0 1.8e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM12693.1 - 0.021 13.7 0.1 0.41 9.5 0.0 2.1 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.17 KFM12693.1 - 0.49 9.7 4.5 0.28 10.5 1.0 2.1 2 1 0 2 2 2 0 RIO1 family Torsin PF06309.6 KFM12694.1 - 3.3e-38 130.4 0.0 6.2e-38 129.5 0.0 1.5 1 0 0 1 1 1 1 Torsin AAA_2 PF07724.9 KFM12694.1 - 9e-05 22.4 0.0 0.00022 21.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 KFM12694.1 - 0.01 16.0 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 KFM12694.1 - 0.013 15.2 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 KFM12694.1 - 0.094 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 KFM12694.1 - 0.1 12.7 0.1 4.1 7.5 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KFM12694.1 - 0.14 13.0 0.0 0.29 11.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain TPR_12 PF13424.1 KFM12695.1 - 1.4e-08 34.5 0.7 2.1e-08 33.9 0.5 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 KFM12695.1 - 1.9e-08 33.8 2.0 0.0002 20.9 0.1 2.7 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 KFM12695.1 - 0.00031 20.2 3.1 0.35 10.5 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFM12695.1 - 0.003 17.3 5.3 0.099 12.6 0.3 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat NARP1 PF12569.3 KFM12695.1 - 0.037 12.7 0.0 0.07 11.8 0.0 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TPR_9 PF13371.1 KFM12695.1 - 0.041 13.7 0.5 0.041 13.7 0.4 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFM12695.1 - 1.6 9.5 13.2 0.34 11.6 2.1 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFM12695.1 - 2.4 9.0 13.2 12 6.8 3.0 3.4 1 1 3 4 4 4 0 Tetratricopeptide repeat Pept_tRNA_hydro PF01195.14 KFM12696.1 - 5.3e-30 104.2 0.0 5.9e-30 104.1 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Urm1 PF09138.6 KFM12697.1 - 4.4e-38 129.3 0.0 4.8e-38 129.1 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 KFM12697.1 - 0.00082 19.7 0.0 0.00097 19.5 0.0 1.1 1 0 0 1 1 1 1 ThiS family AMP-binding PF00501.23 KFM12698.1 - 1.9e-73 247.2 0.0 2.3e-73 247.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFM12698.1 - 2.2e-05 25.3 0.0 4.6e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Coq4 PF05019.8 KFM12699.1 - 6.8e-97 322.7 0.0 7.7e-97 322.5 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Rnk_N PF14760.1 KFM12699.1 - 0.024 14.6 0.0 0.063 13.3 0.0 1.8 1 0 0 1 1 1 0 Rnk N-terminus TruB_N PF01509.13 KFM12700.1 - 8.8e-26 90.8 0.0 1.3e-25 90.3 0.0 1.2 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) DUF904 PF06005.7 KFM12701.1 - 0.16 12.2 1.3 0.2 11.9 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Dynamin_M PF01031.15 KFM12702.1 - 4.4e-97 324.4 7.1 4.4e-97 324.4 4.9 2.2 2 1 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 KFM12702.1 - 8e-42 142.9 0.0 2.5e-41 141.2 0.0 1.9 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KFM12702.1 - 9.4e-27 92.7 2.5 2.4e-26 91.4 1.7 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain PH PF00169.24 KFM12702.1 - 6.1e-11 42.4 0.7 1.3e-10 41.4 0.5 1.5 1 0 0 1 1 1 1 PH domain Ldh_1_N PF00056.18 KFM12702.1 - 0.056 13.2 0.1 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain zf-C2H2_jaz PF12171.3 KFM12703.1 - 1.4e-05 25.1 29.9 0.00014 21.8 0.3 4.7 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM12703.1 - 2e-05 24.5 28.5 0.0015 18.7 4.7 4.5 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KFM12703.1 - 0.032 14.3 1.0 0.032 14.3 0.7 4.3 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.7 KFM12703.1 - 0.092 12.5 15.5 0.37 10.5 8.1 2.4 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) UPF0184 PF03670.8 KFM12704.1 - 1.9e-24 85.6 3.8 2.2e-24 85.4 2.6 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0184) EzrA PF06160.7 KFM12704.1 - 0.029 12.5 1.4 0.029 12.5 0.9 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF948 PF06103.6 KFM12704.1 - 0.036 13.9 0.3 0.041 13.7 0.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) IncA PF04156.9 KFM12704.1 - 0.057 13.0 5.2 0.064 12.8 3.6 1.0 1 0 0 1 1 1 0 IncA protein RasGAP_C PF03836.10 KFM12704.1 - 0.078 12.6 0.5 0.087 12.5 0.4 1.1 1 0 0 1 1 1 0 RasGAP C-terminus CaMBD PF02888.11 KFM12704.1 - 0.13 12.0 0.8 0.18 11.6 0.4 1.5 1 1 1 2 2 2 0 Calmodulin binding domain DUF904 PF06005.7 KFM12704.1 - 1.2 9.4 5.3 1.9 8.8 3.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF904) GST_C_3 PF14497.1 KFM12705.1 - 1.9e-17 63.5 0.2 2.9e-17 62.9 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KFM12705.1 - 1.1e-14 54.3 0.5 1.5e-13 50.7 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 KFM12705.1 - 2.7e-11 43.2 0.1 6.5e-11 42.0 0.1 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_N_2 PF13409.1 KFM12705.1 - 3.8e-09 36.4 0.0 1.4e-08 34.5 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFM12705.1 - 1.5e-05 24.8 0.2 2.9e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFM12705.1 - 2.9e-05 23.8 0.0 5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KFM12705.1 - 0.012 15.8 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain ArsC PF03960.10 KFM12705.1 - 0.04 13.9 0.0 0.092 12.8 0.0 1.7 1 0 0 1 1 1 0 ArsC family SNARE_assoc PF09335.6 KFM12705.1 - 0.12 12.5 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 SNARE associated Golgi protein AAA_13 PF13166.1 KFM12706.1 - 0.0005 18.6 24.8 0.0005 18.6 17.2 4.6 1 1 3 4 4 4 1 AAA domain Myosin_tail_1 PF01576.14 KFM12706.1 - 0.81 7.3 150.0 0.0056 14.4 43.5 2.2 1 1 1 2 2 2 0 Myosin tail ACT_5 PF13710.1 KFM12706.1 - 7 6.5 14.1 6.8 6.5 0.3 4.9 4 1 1 5 5 5 0 ACT domain GLE1 PF07817.8 KFM12707.1 - 7.1e-94 313.5 0.0 7.1e-94 313.5 0.0 2.7 3 1 1 4 4 4 1 GLE1-like protein NatB_MDM20 PF09797.4 KFM12707.1 - 0.0031 16.2 5.3 0.0057 15.4 3.7 1.3 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit WD40 PF00400.27 KFM12708.1 - 3.7e-20 70.9 10.5 0.00028 20.6 0.2 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Fer2_3 PF13085.1 KFM12708.1 - 0.16 11.7 1.3 1.8 8.3 0.1 2.6 2 1 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain NAP PF00956.13 KFM12709.1 - 2.4e-59 200.4 7.7 2.4e-59 200.4 5.4 2.2 2 1 0 2 2 2 1 Nucleosome assembly protein (NAP) Phage_Mu_Gam PF07352.7 KFM12709.1 - 0.00077 19.0 1.4 0.0016 17.9 1.0 1.6 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein DUF904 PF06005.7 KFM12709.1 - 0.0064 16.7 2.1 0.014 15.6 1.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF904) Mst1_SARAH PF11629.3 KFM12709.1 - 0.016 15.0 0.8 0.042 13.6 0.5 1.7 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 ACCA PF03255.9 KFM12709.1 - 0.12 11.9 0.7 0.22 11.0 0.5 1.4 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Pkinase PF00069.20 KFM12710.1 - 4.6e-64 216.0 0.0 1e-63 214.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain HR1 PF02185.11 KFM12710.1 - 2.4e-45 152.1 29.5 9.8e-17 60.4 3.8 3.3 3 0 0 3 3 3 3 Hr1 repeat Pkinase_Tyr PF07714.12 KFM12710.1 - 7.7e-35 120.1 0.0 1.4e-34 119.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KFM12710.1 - 6.2e-08 33.0 0.4 6.2e-08 33.0 0.3 1.8 2 0 0 2 2 2 1 Protein kinase C terminal domain Uds1 PF15456.1 KFM12710.1 - 4e-06 26.8 18.8 0.0017 18.3 0.6 3.4 3 0 0 3 3 3 3 Up-regulated During Septation Kinase-like PF14531.1 KFM12710.1 - 6.9e-05 21.9 0.0 0.00014 20.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like DUF2779 PF11074.3 KFM12710.1 - 0.093 12.7 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function(DUF2779) DUF3416 PF11896.3 KFM12710.1 - 0.6 10.0 10.0 0.23 11.3 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3416) zf-DHHC PF01529.15 KFM12711.1 - 6.4e-37 126.6 6.8 8.2e-37 126.2 4.7 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase Baculo_11_kDa PF06143.6 KFM12711.1 - 0.0037 16.5 2.5 0.019 14.3 0.6 2.2 2 0 0 2 2 2 1 Baculovirus 11 kDa family DUF843 PF05814.6 KFM12711.1 - 0.013 15.2 1.4 0.13 12.0 0.6 2.3 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) DUF912 PF06024.7 KFM12711.1 - 0.053 13.5 0.9 1.4 9.0 0.7 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Pico_P2B PF01552.12 KFM12711.1 - 0.12 12.4 0.2 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 Picornavirus 2B protein DUF3974 PF13120.1 KFM12711.1 - 0.14 11.9 0.3 0.14 11.9 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3974) Mtp PF03821.11 KFM12711.1 - 0.51 9.6 5.3 0.074 12.4 0.4 1.8 2 0 0 2 2 2 0 Golgi 4-transmembrane spanning transporter Arm PF00514.18 KFM12712.1 - 1.1e-08 34.5 4.7 0.085 12.7 0.0 6.9 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat LRR_4 PF12799.2 KFM12712.1 - 0.00053 19.5 9.3 0.04 13.5 0.1 5.3 3 1 3 6 6 6 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM12712.1 - 0.0035 17.0 11.5 0.34 10.7 0.1 4.4 3 1 0 3 3 3 2 Leucine rich repeat RabGAP-TBC PF00566.13 KFM12713.1 - 2.6e-38 131.6 5.0 4.3e-35 121.1 0.4 2.7 2 1 0 2 2 2 2 Rab-GTPase-TBC domain TFIID_20kDa PF03847.8 KFM12713.1 - 0.02 15.1 0.5 0.06 13.6 0.1 2.0 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Methyltrn_RNA_3 PF02598.12 KFM12714.1 - 2.2e-97 325.9 0.0 2.8e-97 325.6 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.14 KFM12714.1 - 0.11 12.4 0.0 1.8 8.4 0.0 2.3 2 0 0 2 2 2 0 SpoU rRNA Methylase family Aminotran_1_2 PF00155.16 KFM12715.1 - 2.8e-56 191.0 0.0 3.2e-56 190.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KFM12715.1 - 0.0016 17.5 0.0 0.0026 16.8 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 KFM12715.1 - 0.0029 15.9 0.0 0.0053 15.0 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF3733 PF12534.3 KFM12716.1 - 2.4e-49 164.4 9.3 3.1e-29 100.0 0.8 2.6 2 0 0 2 2 2 2 Leucine-rich repeat containing protein 8 LRR_4 PF12799.2 KFM12716.1 - 1.2e-42 142.8 54.9 6.4e-12 44.8 1.6 10.2 4 3 8 12 12 12 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM12716.1 - 3.1e-41 138.9 44.6 6.8e-14 51.3 3.2 7.0 2 2 6 8 8 8 7 Leucine rich repeat LRR_1 PF00560.28 KFM12716.1 - 5.6e-13 46.9 46.0 0.00043 19.9 0.1 11.7 13 0 0 13 13 13 6 Leucine Rich Repeat LRR_7 PF13504.1 KFM12716.1 - 3.6e-10 38.3 40.5 0.026 14.6 0.2 13.0 14 0 0 14 14 14 4 Leucine rich repeat PhyH PF05721.8 KFM12717.1 - 3e-62 210.3 0.0 3.8e-62 210.0 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Nup188 PF10487.4 KFM12719.1 - 0 1178.8 0.1 0 1178.8 0.0 1.4 2 0 0 2 2 2 1 Nucleoporin subcomplex protein binding to Pom34 BAR PF03114.13 KFM12720.1 - 1.7e-59 201.1 1.9 2.2e-59 200.7 1.3 1.2 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 KFM12720.1 - 1.5e-10 40.4 0.0 3.2e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM12720.1 - 1.5e-06 27.4 0.0 2.9e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFM12720.1 - 6.2e-06 25.6 0.0 1.1e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR_2 PF10455.4 KFM12720.1 - 7.9e-06 24.9 0.1 1.3e-05 24.3 0.0 1.3 2 0 0 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF2217 PF10265.4 KFM12721.1 - 1.4e-233 776.3 0.6 1.6e-233 776.1 0.4 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2217) PAP2 PF01569.16 KFM12722.1 - 5.9e-19 68.0 5.6 1.1e-18 67.1 3.9 1.4 1 0 0 1 1 1 1 PAP2 superfamily Carn_acyltransf PF00755.15 KFM12723.1 - 3.3e-236 785.0 0.0 3.8e-236 784.8 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase PTPA PF03095.10 KFM12724.1 - 2.6e-116 388.0 0.0 3e-116 387.8 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Methyltransf_PK PF05891.7 KFM12726.1 - 8.7e-93 309.6 0.0 1e-92 309.4 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_11 PF08241.7 KFM12726.1 - 1e-09 38.7 0.0 1.8e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFM12726.1 - 5.3e-09 36.4 0.0 9.7e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFM12726.1 - 4e-08 33.8 0.0 6.2e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFM12726.1 - 9e-07 29.2 0.0 1.5e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 KFM12726.1 - 4.4e-05 22.8 0.1 6.8e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.1 KFM12726.1 - 4.8e-05 22.9 0.0 6.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFM12726.1 - 6e-05 22.2 0.0 7.8e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 KFM12726.1 - 0.00011 21.9 0.0 0.00017 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Dioxygenase_N PF04444.9 KFM12726.1 - 0.0062 16.4 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus MTS PF05175.9 KFM12726.1 - 0.0081 15.5 0.0 0.013 14.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KFM12726.1 - 0.045 13.7 0.0 0.084 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 KFM12726.1 - 0.091 11.6 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Ank_2 PF12796.2 KFM12727.1 - 8.1e-26 90.1 0.0 5e-11 42.7 0.0 4.0 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFM12727.1 - 1.9e-24 84.1 0.3 1.9e-10 39.9 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 KFM12727.1 - 5.4e-20 71.3 0.4 3e-05 24.3 0.0 6.6 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM12727.1 - 1e-15 57.3 1.3 5.8e-09 35.9 0.0 5.3 4 2 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM12727.1 - 3.6e-15 54.5 1.0 8.7e-07 28.5 0.0 6.3 7 0 0 7 7 7 2 Ankyrin repeat SOCS_box PF07525.11 KFM12727.1 - 1e-11 44.4 3.6 2.1e-11 43.4 0.6 2.6 2 0 0 2 2 2 1 SOCS box N_methyl_2 PF13544.1 KFM12727.1 - 0.13 11.8 0.0 0.32 10.5 0.0 1.7 1 0 0 1 1 1 0 Type IV pilin N-term methylation site GFxxxE Homeobox PF00046.24 KFM12728.1 - 1.8e-23 81.9 6.6 3.5e-23 80.9 4.6 1.5 1 0 0 1 1 1 1 Homeobox domain OAR PF03826.12 KFM12728.1 - 8.7e-09 34.6 0.0 2e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.6 KFM12728.1 - 0.00041 19.9 0.3 0.001 18.7 0.1 1.8 2 0 0 2 2 2 1 Homeobox KN domain MAPEG PF01124.13 KFM12729.1 - 1.4e-21 76.4 0.1 1.6e-21 76.2 0.1 1.0 1 0 0 1 1 1 1 MAPEG family Torsin PF06309.6 KFM12730.1 - 7.1e-32 109.9 0.1 1.9e-31 108.6 0.1 1.7 2 0 0 2 2 2 1 Torsin AAA_17 PF13207.1 KFM12730.1 - 0.043 14.6 0.0 0.067 14.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain Torsin PF06309.6 KFM12731.1 - 5.5e-47 158.8 0.1 1.1e-46 157.8 0.0 1.5 2 0 0 2 2 2 1 Torsin AAA PF00004.24 KFM12731.1 - 0.00081 19.6 0.0 0.0015 18.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 KFM12731.1 - 0.002 17.7 0.0 0.0031 17.0 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 KFM12731.1 - 0.0076 16.3 0.0 0.17 12.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain Torsin PF06309.6 KFM12732.1 - 8.7e-48 161.3 0.3 1.4e-47 160.6 0.2 1.4 1 0 0 1 1 1 1 Torsin AAA PF00004.24 KFM12732.1 - 0.0045 17.1 0.0 0.0083 16.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFM12732.1 - 0.034 13.8 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KFM12732.1 - 0.037 14.1 0.1 4 7.5 0.0 2.3 1 1 1 2 2 2 0 AAA domain Hep_59 PF07052.6 KFM12733.1 - 1.5e-29 102.3 4.7 1.5e-29 102.3 3.3 2.6 2 0 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 UCH PF00443.24 KFM12734.1 - 8.3e-65 218.5 0.0 9.7e-64 215.0 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFM12734.1 - 4.9e-25 88.5 0.0 5.3e-24 85.1 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 KFM12734.1 - 1.6e-24 86.1 0.9 1e-14 54.7 0.0 2.7 2 0 0 2 2 2 2 DUSP domain zf-UBP PF02148.14 KFM12734.1 - 4.9e-16 58.5 5.2 4.9e-16 58.5 3.6 2.9 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein FCH PF00611.18 KFM12735.1 - 7.7e-21 74.0 3.9 7.7e-21 74.0 2.7 3.8 4 0 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 KFM12735.1 - 1.2e-10 40.8 0.1 2.5e-10 39.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM12735.1 - 2.6e-10 39.5 0.1 5.9e-10 38.3 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFM12735.1 - 1.8e-06 27.3 0.1 4.1e-06 26.1 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 KFM12735.1 - 3.5e-05 23.8 0.3 7.2e-05 22.9 0.2 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain HR1 PF02185.11 KFM12735.1 - 4.9e-05 22.9 1.9 4.9e-05 22.9 1.3 3.5 4 1 0 4 4 4 1 Hr1 repeat Lzipper-MIP1 PF14389.1 KFM12735.1 - 0.00017 21.5 1.7 0.0006 19.8 1.2 1.9 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 Uds1 PF15456.1 KFM12735.1 - 0.0019 18.1 1.1 0.0019 18.1 0.8 4.3 2 2 2 4 4 3 1 Up-regulated During Septation PG_binding_4 PF12229.3 KFM12735.1 - 0.0092 16.2 0.1 0.037 14.2 0.1 2.1 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Laminin_II PF06009.7 KFM12735.1 - 0.19 11.5 11.1 5.1 6.8 2.3 3.4 2 2 1 3 3 3 0 Laminin Domain II Spectrin PF00435.16 KFM12735.1 - 0.2 11.9 23.1 0.074 13.3 2.2 4.0 2 1 1 3 3 3 0 Spectrin repeat DUF4239 PF14023.1 KFM12735.1 - 4.8 6.4 9.4 15 4.8 0.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4239) Lung_7-TM_R PF06814.8 KFM12736.1 - 1.6e-94 316.1 7.7 2e-94 315.8 5.3 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor Arginosuc_synth PF00764.14 KFM12737.1 - 2.3e-144 481.1 0.0 4.2e-86 289.4 0.0 2.0 2 0 0 2 2 2 2 Arginosuccinate synthase QueC PF06508.8 KFM12737.1 - 6.9e-05 22.2 0.0 0.00011 21.5 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 KFM12737.1 - 0.00087 18.8 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.11 KFM12737.1 - 0.0029 16.2 0.0 0.0045 15.5 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase KH_1 PF00013.24 KFM12738.1 - 5.4e-67 221.3 15.7 3e-19 68.3 0.1 4.2 4 0 0 4 4 4 4 KH domain KH_3 PF13014.1 KFM12738.1 - 7.6e-42 140.3 24.7 1.8e-11 43.4 0.5 4.8 5 0 0 5 5 5 4 KH domain KH_2 PF07650.12 KFM12738.1 - 3.6e-22 77.7 9.5 2.1e-05 24.0 0.2 4.4 4 0 0 4 4 4 4 KH domain KH_4 PF13083.1 KFM12738.1 - 4.7e-12 45.3 7.0 0.02 14.5 0.0 4.3 4 0 0 4 4 4 4 KH domain KH_5 PF13184.1 KFM12738.1 - 7.2e-05 22.5 6.6 4.3 7.2 0.0 4.4 4 0 0 4 4 4 3 NusA-like KH domain DUF1897 PF09005.5 KFM12738.1 - 0.00039 19.8 11.6 0.00085 18.7 8.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1897) zf-H2C2_2 PF13465.1 KFM12739.1 - 3.4e-13 49.1 6.4 7.9e-07 29.0 0.5 2.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFM12739.1 - 3.6e-06 26.9 3.0 3.6e-06 26.9 2.1 2.2 3 0 0 3 3 2 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KFM12739.1 - 0.00044 20.2 0.1 0.00069 19.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KFM12739.1 - 0.00045 20.3 2.8 0.00045 20.3 1.9 1.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.2 KFM12739.1 - 0.0024 18.0 0.7 0.0024 18.0 0.5 1.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KFM12739.1 - 0.017 15.2 0.1 0.017 15.1 0.1 1.1 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 KFM12739.1 - 0.04 13.8 0.6 0.066 13.1 0.4 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-BED PF02892.10 KFM12739.1 - 0.047 13.4 0.8 0.059 13.1 0.6 1.3 1 0 0 1 1 1 0 BED zinc finger zf-H2C2_5 PF13909.1 KFM12739.1 - 0.052 13.8 0.8 0.052 13.8 0.5 2.2 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.1 KFM12739.1 - 0.1 12.3 2.9 0.18 11.5 2.0 1.5 1 1 0 1 1 1 0 zinc-finger of a C2HC-type Elf1 PF05129.8 KFM12739.1 - 0.11 12.2 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-Di19 PF05605.7 KFM12739.1 - 0.12 12.5 0.4 0.13 12.3 0.3 1.2 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding ECR1_N PF14382.1 KFM12740.1 - 1.7e-15 56.0 0.2 3.1e-15 55.1 0.1 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Ribosomal_L14 PF00238.14 KFM12740.1 - 0.003 17.2 0.0 3.2 7.5 0.0 2.5 2 0 0 2 2 2 2 Ribosomal protein L14p/L23e EXOSC1 PF10447.4 KFM12740.1 - 0.0071 16.2 0.1 1.1 9.2 0.0 2.4 2 0 0 2 2 2 2 Exosome component EXOSC1/CSL4 S1 PF00575.18 KFM12740.1 - 0.097 12.7 0.0 17 5.5 0.0 2.5 2 0 0 2 2 2 0 S1 RNA binding domain Pkinase_Tyr PF07714.12 KFM12741.1 - 2.4e-99 331.6 0.0 3.4e-99 331.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM12741.1 - 3.3e-51 173.9 0.0 6.1e-51 173.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain F_actin_bind PF08919.5 KFM12741.1 - 5.4e-30 103.3 0.1 1.2e-29 102.2 0.1 1.6 1 0 0 1 1 1 1 F-actin binding SH2 PF00017.19 KFM12741.1 - 1e-23 82.8 0.2 2.6e-23 81.6 0.1 1.7 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.23 KFM12741.1 - 1.6e-12 46.6 0.0 2.8e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFM12741.1 - 1.4e-10 40.5 0.0 2.8e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFM12741.1 - 4.1e-08 32.5 0.0 8.1e-08 31.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 KFM12741.1 - 3.2e-05 24.0 0.2 8.6e-05 22.6 0.2 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain Kinase-like PF14531.1 KFM12741.1 - 0.0018 17.3 0.0 0.0027 16.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like SH3_6 PF12913.2 KFM12741.1 - 0.079 12.2 0.0 0.18 11.0 0.0 1.6 1 0 0 1 1 1 0 SH3 domain of the SH3b1 type SH3_4 PF06347.8 KFM12741.1 - 0.12 11.9 0.2 0.29 10.7 0.1 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain RFamide_26RFa PF11109.3 KFM12742.1 - 9.5e-29 99.9 1.5 1.1e-28 99.7 1.0 1.0 1 0 0 1 1 1 1 Orexigenic neuropeptide Qrfp/P518 EF-hand_1 PF00036.27 KFM12743.1 - 0.0023 17.0 3.3 0.091 12.1 0.4 2.8 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 KFM12743.1 - 0.0046 17.0 0.1 0.0074 16.4 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KFM12743.1 - 0.0051 16.5 0.0 0.068 13.0 0.0 2.3 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.1 KFM12743.1 - 0.043 13.4 0.6 0.95 9.1 0.2 2.4 2 0 0 2 2 2 0 EF-hand domain pair PAP2 PF01569.16 KFM12746.1 - 1.9e-16 59.9 3.5 3.1e-16 59.2 2.5 1.3 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 KFM12746.1 - 0.097 12.9 0.5 0.097 12.9 0.3 1.6 2 0 0 2 2 2 0 PAP2 superfamily C-terminal BAT2_N PF07001.6 KFM12747.1 - 1.7e-80 269.8 9.7 1.7e-80 269.8 6.7 5.7 6 2 0 6 6 6 1 BAT2 N-terminus PMT PF02366.13 KFM12748.1 - 5.3e-88 294.5 25.0 5.3e-88 294.5 17.4 2.3 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KFM12748.1 - 1.3e-13 50.9 0.6 2.4e-13 50.0 0.4 1.3 1 0 0 1 1 1 1 MIR domain PRK PF00485.13 KFM12749.1 - 6e-44 149.9 1.0 6.8e-44 149.7 0.7 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 KFM12749.1 - 0.019 15.2 0.3 0.056 13.7 0.2 1.7 1 1 0 1 1 1 0 AAA domain Dispanin PF04505.7 KFM12750.1 - 1.2e-11 43.9 0.8 1.5e-11 43.6 0.6 1.1 1 0 0 1 1 1 1 Interferon-induced transmembrane protein Choline_transpo PF04515.7 KFM12750.1 - 0.051 12.3 1.8 0.056 12.1 1.3 1.2 1 0 0 1 1 1 0 Plasma-membrane choline transporter RasGEF PF00617.14 KFM12751.1 - 5.4e-54 182.7 0.4 1.2e-53 181.6 0.3 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KFM12751.1 - 1.4e-09 38.0 0.5 7.1e-09 35.7 0.3 2.3 1 0 0 1 1 1 1 RasGEF N-terminal motif Med27 PF11571.3 KFM12752.1 - 2.8e-26 91.4 0.5 4.8e-26 90.7 0.0 1.6 2 0 0 2 2 2 1 Mediator complex subunit 27 Laminin_N PF00055.12 KFM12754.1 - 1e-28 99.9 0.0 1e-28 99.9 0.0 1.7 2 0 0 2 2 2 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.19 KFM12754.1 - 2.9e-21 75.1 68.2 3.8e-09 36.3 9.5 4.7 3 1 1 4 4 4 3 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 KFM12754.1 - 0.0024 17.9 9.9 0.0024 17.9 6.9 6.2 6 0 0 6 6 6 1 EGF-like domain BNR PF02012.15 KFM12754.1 - 0.012 15.3 1.1 0.93 9.5 0.0 3.1 2 0 0 2 2 2 0 BNR/Asp-box repeat hEGF PF12661.2 KFM12754.1 - 0.054 13.5 0.6 0.054 13.5 0.4 5.9 8 0 0 8 8 8 0 Human growth factor-like EGF EGF PF00008.22 KFM12754.1 - 0.38 10.7 34.8 0.037 13.9 6.0 5.1 3 1 0 3 3 3 0 EGF-like domain AAA_11 PF13086.1 KFM12755.1 - 6.8e-61 205.8 2.3 6.8e-61 205.8 1.6 3.8 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.1 KFM12755.1 - 2.5e-55 186.9 0.4 9.8e-55 185.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KFM12755.1 - 6.7e-10 38.5 0.0 4.6e-09 35.8 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KFM12755.1 - 7.9e-07 28.8 0.7 0.012 15.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 KFM12755.1 - 0.00014 22.0 5.2 0.00037 20.6 0.4 3.6 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KFM12755.1 - 0.00018 21.5 0.0 0.00063 19.7 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain UvrD_C_2 PF13538.1 KFM12755.1 - 0.0058 16.7 0.1 0.04 14.0 0.0 2.5 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Helicase_RecD PF05127.9 KFM12755.1 - 0.017 14.7 0.1 0.29 10.7 0.0 3.1 4 0 0 4 4 4 0 Helicase Myb_DNA-bind_6 PF13921.1 KFM12756.1 - 6.2e-18 64.6 9.4 1.2e-15 57.3 0.5 3.5 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KFM12756.1 - 1.6e-14 53.6 8.1 1.3e-08 34.7 0.1 4.4 3 1 1 4 4 4 3 Myb-like DNA-binding domain Poxvirus_B22R_N PF13169.1 KFM12756.1 - 0.0074 16.4 4.6 0.01 16.0 0.1 3.0 3 0 0 3 3 3 1 Poxvirus B22R protein N-terminal Smr PF01713.16 KFM12756.1 - 0.059 13.5 0.1 4.4 7.5 0.0 2.6 2 0 0 2 2 2 0 Smr domain CarD_CdnL_TRCF PF02559.11 KFM12756.1 - 1.8 8.6 5.2 2.6 8.1 0.9 3.1 1 1 2 3 3 3 0 CarD-like/TRCF domain Homeobox PF00046.24 KFM12757.1 - 1e-21 76.2 2.5 1.1e-21 76.1 1.7 1.0 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 KFM12757.1 - 0.013 14.5 0.4 0.014 14.4 0.3 1.1 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.6 KFM12757.1 - 0.11 12.2 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Homeobox KN domain DEAD PF00270.24 KFM12758.1 - 3.7e-41 140.4 0.0 9.8e-41 139.0 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFM12758.1 - 7.3e-24 83.4 0.0 2e-23 82.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 KFM12758.1 - 3.5e-16 58.4 0.1 7.4e-16 57.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 KFM12758.1 - 0.00057 19.7 0.0 0.0018 18.1 0.0 1.9 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 KFM12758.1 - 0.0034 16.7 0.3 0.062 12.5 0.1 2.3 2 0 0 2 2 2 1 SecA DEAD-like domain Med29 PF11568.3 KFM12758.1 - 0.0063 16.5 0.2 5.9 6.9 0.0 2.9 2 0 0 2 2 2 2 Mediator complex subunit 29 zf-TFIIIC PF12660.2 KFM12759.1 - 7.6e-23 80.2 1.7 2e-22 78.9 1.2 1.7 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex TFIIIC_delta PF12657.2 KFM12759.1 - 6e-15 55.3 0.0 2.6e-14 53.3 0.0 2.0 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term ADK PF00406.17 KFM12760.1 - 0.0094 15.8 0.1 0.012 15.5 0.1 1.1 1 0 0 1 1 1 1 Adenylate kinase DUF4375 PF14300.1 KFM12760.1 - 0.1 12.6 1.0 0.12 12.3 0.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) ADK PF00406.17 KFM12761.1 - 2.5e-41 141.0 0.0 1.2e-23 83.7 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.1 KFM12761.1 - 1.7e-17 64.3 0.0 1.7e-09 38.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KFM12761.1 - 2e-13 50.7 0.0 2.4e-09 37.5 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KFM12761.1 - 8.5e-13 48.3 0.0 8.2e-08 32.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 KFM12761.1 - 1.8e-07 31.3 0.1 0.0027 17.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFM12761.1 - 7e-06 26.1 0.0 0.013 15.4 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 KFM12761.1 - 4.6e-05 23.5 0.0 0.31 11.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain KTI12 PF08433.5 KFM12761.1 - 0.00016 21.0 0.0 0.43 9.7 0.0 2.4 2 0 0 2 2 2 2 Chromatin associated protein KTI12 ABC_tran PF00005.22 KFM12761.1 - 0.00035 20.8 0.0 0.3 11.3 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_19 PF13245.1 KFM12761.1 - 0.00051 19.7 0.0 0.48 10.2 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain RNA_helicase PF00910.17 KFM12761.1 - 0.0013 18.9 0.0 2.5 8.3 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 KFM12761.1 - 0.002 18.1 0.0 0.6 10.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KFM12761.1 - 0.0022 17.4 0.0 0.22 10.9 0.0 2.6 3 0 0 3 3 2 1 AAA domain RuvB_N PF05496.7 KFM12761.1 - 0.0025 16.8 0.0 0.75 8.7 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 KFM12761.1 - 0.0026 16.9 0.0 0.25 10.5 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 KFM12761.1 - 0.005 16.3 0.0 2.8 7.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain IstB_IS21 PF01695.12 KFM12761.1 - 0.0061 15.9 0.0 3.1 7.1 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_5 PF07728.9 KFM12761.1 - 0.0068 16.1 0.1 4.8 6.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PMBR PF09373.5 KFM12761.1 - 0.0072 16.2 0.0 0.17 11.9 0.0 2.5 2 0 0 2 2 2 1 Pseudomurein-binding repeat MobB PF03205.9 KFM12761.1 - 0.0084 15.8 0.1 0.61 9.7 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KFM12761.1 - 0.009 15.4 0.0 3.6 6.9 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain Sigma54_activat PF00158.21 KFM12761.1 - 0.013 14.9 0.0 1.6 8.1 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 KFM12761.1 - 0.017 15.1 0.0 8.1 6.5 0.0 2.6 2 1 0 2 2 2 0 Sigma-54 interaction domain Thymidylate_kin PF02223.12 KFM12761.1 - 0.025 13.9 0.0 7.5 5.8 0.0 3.1 3 0 0 3 3 3 0 Thymidylate kinase APS_kinase PF01583.15 KFM12761.1 - 0.032 13.9 0.0 0.64 9.6 0.0 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase Zeta_toxin PF06414.7 KFM12761.1 - 0.035 13.2 0.0 1.5 7.8 0.0 2.4 3 0 0 3 3 2 0 Zeta toxin NACHT PF05729.7 KFM12761.1 - 0.058 13.0 0.0 1.4 8.5 0.0 2.4 2 0 0 2 2 2 0 NACHT domain ResIII PF04851.10 KFM12761.1 - 0.064 13.0 0.0 3.5 7.4 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NB-ARC PF00931.17 KFM12761.1 - 0.077 11.8 0.0 0.51 9.1 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain PRK PF00485.13 KFM12761.1 - 0.097 12.2 0.0 0.62 9.5 0.0 2.1 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family AAA_14 PF13173.1 KFM12761.1 - 0.1 12.4 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KFM12761.1 - 0.11 11.9 0.0 12 5.3 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family T2SE PF00437.15 KFM12761.1 - 0.12 11.2 0.0 4.2 6.1 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF4561 PF15120.1 KFM12762.1 - 1.5e-83 278.3 2.2 1.8e-83 278.1 1.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4561) Allexi_40kDa PF05549.6 KFM12762.1 - 0.016 14.4 0.1 0.021 14.1 0.1 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein Crust_neurohorm PF01147.12 KFM12762.1 - 0.046 13.0 0.3 0.095 12.0 0.2 1.6 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family Hamartin PF04388.7 KFM12763.1 - 2.2e-251 836.2 0.0 2.2e-251 836.2 0.0 2.2 2 0 0 2 2 2 1 Hamartin protein zf-H2C2_2 PF13465.1 KFM12764.1 - 4.6e-33 111.8 43.4 7.3e-08 32.3 1.3 7.3 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.21 KFM12764.1 - 5.5e-29 98.7 45.6 1.2e-05 25.3 1.0 6.7 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM12764.1 - 1.9e-22 77.8 38.2 0.0012 18.9 0.2 6.5 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM12764.1 - 2.9e-16 59.0 27.6 0.0074 16.3 0.0 7.0 7 0 0 7 7 6 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM12764.1 - 8.1e-09 35.3 37.2 0.0064 16.6 0.3 7.1 7 0 0 7 7 7 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFM12764.1 - 3.9e-08 32.9 32.5 0.0002 21.1 1.0 6.5 6 0 0 6 6 6 3 C2H2-type zinc finger zf-CHCC PF10276.4 KFM12764.1 - 0.00018 21.2 9.1 0.079 12.8 0.1 4.2 4 0 0 4 4 4 2 Zinc-finger domain Prok-RING_1 PF14446.1 KFM12764.1 - 0.0013 18.3 14.9 6.7 6.5 0.0 6.2 6 0 0 6 6 6 0 Prokaryotic RING finger family 1 Ta0938 PF11494.3 KFM12764.1 - 0.0022 18.1 0.3 0.7 10.0 0.0 2.5 2 0 0 2 2 2 1 Ta0938 Zn-ribbon_8 PF09723.5 KFM12764.1 - 0.0032 17.4 25.4 3 7.8 0.1 5.9 4 2 1 5 5 5 1 Zinc ribbon domain Rpr2 PF04032.11 KFM12764.1 - 0.0053 16.5 11.8 0.042 13.7 0.1 3.4 3 0 0 3 3 3 2 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-BED PF02892.10 KFM12764.1 - 0.0059 16.3 33.3 0.0084 15.8 1.3 5.8 4 2 2 6 6 6 2 BED zinc finger FYVE PF01363.16 KFM12764.1 - 0.022 14.6 28.2 0.95 9.4 7.4 4.0 1 1 2 3 3 3 0 FYVE zinc finger zf-Di19 PF05605.7 KFM12764.1 - 0.031 14.3 28.2 6.5 6.9 6.7 4.6 1 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding C1_1 PF00130.17 KFM12764.1 - 0.046 13.4 29.9 0.17 11.6 2.8 3.9 4 0 0 4 4 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) GAGA PF09237.6 KFM12764.1 - 0.15 11.6 7.7 5.8 6.5 0.1 3.8 2 2 2 4 4 4 0 GAGA factor BolA PF01722.13 KFM12764.1 - 0.5 10.3 6.9 18 5.3 0.2 3.6 2 2 1 3 3 3 0 BolA-like protein zf-C2H2_2 PF12756.2 KFM12764.1 - 0.72 9.9 29.1 1.8 8.7 0.2 6.0 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-CHY PF05495.7 KFM12764.1 - 0.89 9.7 24.3 5.3 7.2 4.0 3.6 1 1 1 2 2 2 0 CHY zinc finger PyrI_C PF02748.10 KFM12764.1 - 2.3 7.7 16.5 2.5 7.6 0.1 5.3 3 1 3 6 6 6 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain HypA PF01155.14 KFM12764.1 - 2.7 7.6 14.1 1.7 8.3 2.2 3.4 1 1 3 4 4 4 0 Hydrogenase expression/synthesis hypA family Mut7-C PF01927.11 KFM12764.1 - 6.3 6.7 12.0 9 6.2 2.8 3.3 1 1 1 2 2 2 0 Mut7-C RNAse domain C1_2 PF03107.11 KFM12764.1 - 7.7 6.7 19.8 21 5.3 0.1 5.9 6 0 0 6 6 6 0 C1 domain COesterase PF00135.23 KFM12765.1 - 7.9e-156 519.8 0.0 8.9e-156 519.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFM12765.1 - 1e-08 35.0 0.0 2.8e-08 33.5 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFM12765.1 - 3.8e-06 26.2 0.0 6.1e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Pou PF00157.12 KFM12765.1 - 0.091 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain Abhydrolase_5 PF12695.2 KFM12765.1 - 0.12 12.0 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Tau95 PF09734.4 KFM12766.1 - 1e-60 205.6 1.4 1.7e-60 204.9 1.0 1.3 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit Glyco_transf_6 PF03414.8 KFM12767.1 - 5.1e-147 488.7 0.0 6.1e-147 488.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 6 Glyco_tranf_2_4 PF13704.1 KFM12767.1 - 0.09 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF4456 PF14644.1 KFM12768.1 - 9.8e-57 191.5 9.0 1.1e-56 191.3 6.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4456) DUF842 PF05811.8 KFM12768.1 - 0.79 9.1 5.8 0.47 9.9 0.7 2.3 1 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) DUF837 PF05769.6 KFM12769.1 - 0.021 14.3 0.5 0.062 12.8 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF837) ApoC-I PF04691.7 KFM12769.1 - 0.088 12.5 0.0 0.41 10.3 0.0 2.0 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) DUF4455 PF14643.1 KFM12770.1 - 9.3e-39 133.3 3.9 1e-38 133.2 2.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4455) SURF6 PF04935.7 KFM12771.1 - 1.1e-46 158.7 67.6 1.1e-46 158.7 46.8 2.2 2 0 0 2 2 2 1 Surfeit locus protein 6 CRF PF00473.12 KFM12771.1 - 1.8 8.7 0.0 1.8 8.7 0.0 5.0 4 0 0 4 4 4 0 Corticotropin-releasing factor family Med22 PF06179.7 KFM12772.1 - 1.3e-34 118.5 4.9 1.7e-34 118.0 3.4 1.2 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex UPRTase PF14681.1 KFM12772.1 - 0.021 14.0 0.0 0.04 13.1 0.0 1.5 2 0 0 2 2 2 0 Uracil phosphoribosyltransferase Ribosomal_L7Ae PF01248.21 KFM12773.1 - 7.6e-24 83.0 0.3 3.3e-23 81.0 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SURF1 PF02104.10 KFM12774.1 - 6.7e-57 192.7 0.0 8.1e-57 192.4 0.0 1.1 1 0 0 1 1 1 1 SURF1 family SURF2 PF05477.6 KFM12775.1 - 4.5e-95 317.4 11.7 5.3e-95 317.1 8.1 1.0 1 0 0 1 1 1 1 Surfeit locus protein 2 (SURF2) SURF4 PF02077.10 KFM12776.1 - 5.8e-123 409.4 9.6 6.5e-123 409.3 6.6 1.0 1 0 0 1 1 1 1 SURF4 family DoxX PF07681.7 KFM12776.1 - 0.018 15.4 0.1 0.018 15.4 0.1 3.4 4 1 1 5 5 5 0 DoxX Pkinase PF00069.20 KFM12777.1 - 4.6e-33 114.4 0.6 5e-33 114.3 0.4 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM12777.1 - 1.1e-25 90.1 1.5 1.2e-25 90.0 1.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM12777.1 - 1.2e-06 27.6 0.0 1.4e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFM12777.1 - 0.0014 17.7 0.1 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Arm PF00514.18 KFM12778.1 - 1.2 9.1 8.6 2.2 8.2 0.2 4.3 4 1 0 4 4 4 0 Armadillo/beta-catenin-like repeat RNase_T PF00929.19 KFM12779.1 - 1.3e-27 97.0 0.0 2.1e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 KFM12779.1 - 7.5e-06 25.5 0.0 2.1e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 3'-5' exonuclease Reprolysin_3 PF13582.1 KFM12780.1 - 2.2e-05 24.9 0.0 2.4e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFM12780.1 - 0.024 14.1 0.0 0.025 14.1 0.0 1.1 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFM12780.1 - 0.039 14.0 0.0 0.039 14.0 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.14 KFM12780.1 - 0.039 13.5 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease CUB PF00431.15 KFM12781.1 - 0.00055 19.9 0.1 0.0035 17.4 0.0 2.0 2 0 0 2 2 2 1 CUB domain Cg6151-P PF10233.4 KFM12782.1 - 9e-36 122.2 4.3 1.1e-35 122.0 3.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF4191 PF13829.1 KFM12782.1 - 0.068 12.2 1.8 0.074 12.1 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4191) Sugar_tr PF00083.19 KFM12783.1 - 2.6e-81 273.5 21.0 3.2e-81 273.1 14.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFM12783.1 - 4.4e-24 84.8 29.8 4.4e-24 84.8 20.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFM12783.1 - 0.00016 20.0 2.4 0.00016 20.0 1.7 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF3522 PF12036.3 KFM12784.1 - 7.7e-60 201.8 6.4 9.4e-60 201.5 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) Oxidored_q5_N PF01059.12 KFM12784.1 - 0.028 14.2 3.8 0.19 11.6 2.3 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus ADAM_spacer1 PF05986.9 KFM12785.1 - 3.1e-27 94.6 0.1 4.9e-27 94.0 0.1 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 TSP_1 PF00090.14 KFM12785.1 - 6e-20 71.1 112.8 3.1e-06 27.1 3.4 9.6 9 2 0 9 9 9 7 Thrombospondin type 1 domain PLAC PF08686.6 KFM12785.1 - 8e-12 45.2 9.0 4.8e-11 42.7 6.2 2.6 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain FAM163 PF15069.1 KFM12786.1 - 8.7e-53 178.7 0.0 9.7e-53 178.5 0.0 1.0 1 0 0 1 1 1 1 FAM163 family Herpes_LMP2 PF07415.6 KFM12786.1 - 0.0059 15.2 3.1 0.03 12.9 0.3 2.0 2 0 0 2 2 2 2 Gammaherpesvirus latent membrane protein (LMP2) protein DUF4006 PF13179.1 KFM12786.1 - 0.011 15.2 2.7 0.019 14.4 1.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF4006) EphA2_TM PF14575.1 KFM12786.1 - 0.093 13.1 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain HCV_NS4a PF01006.15 KFM12786.1 - 2.7 7.6 5.4 2.8 7.5 2.2 2.0 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4a Cu2_monoox_C PF03712.10 KFM12787.1 - 1.3e-49 167.5 0.1 3.8e-49 166.0 0.0 1.8 2 0 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.15 KFM12787.1 - 7.9e-44 148.8 0.2 1.3e-43 148.1 0.1 1.3 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain DOMON PF03351.12 KFM12787.1 - 6.7e-22 77.7 0.0 1e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 DOMON domain RhoGEF PF00621.15 KFM12788.1 - 2.5e-39 135.0 8.4 2.5e-39 135.0 5.8 2.1 2 0 0 2 2 2 1 RhoGEF domain SH3_2 PF07653.12 KFM12788.1 - 7.1e-29 99.0 0.7 2.3e-14 52.6 0.1 3.7 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.23 KFM12788.1 - 9.2e-22 76.1 0.6 2.1e-12 46.2 0.1 2.7 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 KFM12788.1 - 1e-20 73.0 1.9 2.1e-11 43.2 0.1 2.9 3 0 0 3 3 3 2 Variant SH3 domain SH2 PF00017.19 KFM12788.1 - 8.5e-17 60.7 0.2 2.8e-16 59.0 0.1 2.0 1 0 0 1 1 1 1 SH2 domain C1_1 PF00130.17 KFM12788.1 - 4.6e-10 39.0 2.7 9.5e-10 38.0 1.8 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.24 KFM12788.1 - 2.4e-07 30.9 0.7 2.4e-07 30.9 0.5 1.9 2 0 0 2 2 1 1 PH domain SH3_3 PF08239.6 KFM12788.1 - 9.1e-05 22.5 0.8 0.08 13.1 0.3 3.2 3 0 0 3 3 3 1 Bacterial SH3 domain CAMSAP_CH PF11971.3 KFM12788.1 - 0.005 16.4 0.0 0.018 14.6 0.0 2.1 1 0 0 1 1 1 1 CAMSAP CH domain PH_10 PF15411.1 KFM12788.1 - 0.0099 16.0 2.6 0.19 11.9 1.8 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain C1_2 PF03107.11 KFM12788.1 - 0.059 13.4 1.7 0.16 12.1 1.2 1.8 1 0 0 1 1 1 0 C1 domain CotJB PF12652.2 KFM12788.1 - 0.08 13.0 2.8 2.2 8.4 0.0 2.8 2 0 0 2 2 2 0 CotJB protein Prok-RING_1 PF14446.1 KFM12788.1 - 0.38 10.5 7.0 0.035 13.8 1.3 1.9 2 0 0 2 2 1 0 Prokaryotic RING finger family 1 tRNA-synt_1 PF00133.17 KFM12789.1 - 5e-235 781.1 0.0 1.4e-234 779.6 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KFM12789.1 - 3.2e-26 91.9 0.3 8.4e-26 90.5 0.1 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KFM12789.1 - 2.2e-17 62.7 0.6 2.8e-05 22.9 0.0 4.4 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 KFM12789.1 - 0.014 14.5 0.0 0.055 12.5 0.0 2.0 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain E1-E2_ATPase PF00122.15 KFM12790.1 - 3.8e-55 186.4 1.2 8.1e-55 185.3 0.8 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFM12790.1 - 5.9e-44 149.7 6.2 1.7e-43 148.2 2.0 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus ATP_Ca_trans_C PF12424.3 KFM12790.1 - 7.2e-30 103.1 0.0 1.7e-29 101.9 0.0 1.7 1 0 0 1 1 1 1 Plasma membrane calcium transporter ATPase C terminal Hydrolase PF00702.21 KFM12790.1 - 3.9e-25 89.5 0.0 1.4e-24 87.7 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFM12790.1 - 5.1e-16 57.8 0.0 3e-15 55.4 0.0 2.4 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KFM12790.1 - 8.3e-16 57.7 0.0 1.9e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KFM12790.1 - 1.6e-14 54.5 0.0 3.1e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFM12790.1 - 1.9e-07 30.9 2.1 1.6e-05 24.6 0.3 2.6 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase SNF PF00209.13 KFM12791.1 - 6.8e-248 823.3 38.0 7.8e-248 823.1 26.3 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.13 KFM12792.1 - 6.2e-234 777.2 41.4 7.2e-234 777.0 28.7 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family 7tm_1 PF00001.16 KFM12794.1 - 5.3e-68 228.9 7.3 1.5e-67 227.4 5.1 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM12794.1 - 1.6e-09 37.3 11.2 4.8e-06 25.9 4.1 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM12794.1 - 0.0032 16.6 8.1 0.0032 16.6 5.6 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Serpentine_r_xa PF03383.10 KFM12794.1 - 0.023 14.4 0.8 0.023 14.4 0.6 1.9 2 0 0 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa ThiF PF00899.16 KFM12795.1 - 1.8e-34 118.5 0.0 2.8e-34 117.8 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 KFM12795.1 - 0.0019 18.2 0.2 0.0075 16.3 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase VGLL4 PF15245.1 KFM12796.1 - 9.8e-97 322.9 5.1 9.8e-97 322.9 3.5 2.1 2 1 1 3 3 3 1 Transcription cofactor vestigial-like protein 4 Vg_Tdu PF07545.9 KFM12796.1 - 0.017 14.5 0.0 5.9 6.4 0.0 2.4 2 0 0 2 2 2 0 Vestigial/Tondu family DUF3868 PF12984.2 KFM12796.1 - 0.022 14.2 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3868) Mmp37 PF09139.6 KFM12797.1 - 3.2e-93 312.3 0.0 3.5e-93 312.2 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 Synapsin_C PF02750.9 KFM12798.1 - 4.9e-129 427.4 0.7 6.2e-129 427.1 0.5 1.1 1 0 0 1 1 1 1 Synapsin, ATP binding domain Synapsin PF02078.11 KFM12798.1 - 7.3e-16 58.1 0.0 1.5e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Synapsin, N-terminal domain RimK PF08443.6 KFM12798.1 - 1.6e-05 24.4 0.0 6.6e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 RimK-like ATP-grasp domain DUF605 PF04652.11 KFM12798.1 - 0.0042 16.5 31.1 0.0052 16.2 21.5 1.1 1 0 0 1 1 1 1 Vta1 like PAT1 PF09770.4 KFM12798.1 - 0.41 8.8 49.7 0.56 8.3 34.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TIMP PF00965.12 KFM12799.1 - 1.1e-59 201.0 4.2 1.2e-59 200.9 2.9 1.0 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase NTR PF01759.16 KFM12799.1 - 0.034 13.6 0.3 0.047 13.2 0.1 1.4 1 1 0 1 1 1 0 UNC-6/NTR/C345C module CH PF00307.26 KFM12799.1 - 0.09 12.8 0.1 0.14 12.1 0.1 1.4 1 1 0 1 1 1 0 Calponin homology (CH) domain PPARgamma_N PF12577.3 KFM12800.1 - 1.4e-34 118.2 1.8 3.1e-34 117.1 1.3 1.6 1 0 0 1 1 1 1 PPAR gamma N-terminal region Hormone_recep PF00104.25 KFM12800.1 - 7.5e-31 106.8 0.6 1.7e-30 105.6 0.4 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFM12800.1 - 1.3e-27 95.8 15.0 2.5e-27 94.8 10.4 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) tRNA_int_endo_N PF02778.9 KFM12801.1 - 1.6e-20 72.4 0.3 2.2e-14 52.7 0.2 2.5 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain tRNA_int_endo PF01974.12 KFM12801.1 - 4.7e-18 64.7 0.0 9.3e-18 63.8 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain zf-CCCH PF00642.19 KFM12802.1 - 2.8e-21 74.7 29.1 1.4e-06 27.8 2.3 4.6 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_2 PF13639.1 KFM12802.1 - 4.7e-06 26.3 8.9 4.7e-06 26.3 6.1 3.1 3 0 0 3 3 3 1 Ring finger domain zf-CCCH_2 PF14608.1 KFM12802.1 - 4.1e-05 23.4 27.4 0.024 14.6 0.3 5.7 5 1 0 5 5 5 3 Zinc finger C-x8-C-x5-C-x3-H type zf-C3HC4 PF00097.20 KFM12802.1 - 5.2e-05 22.8 10.6 5.2e-05 22.8 7.4 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM12802.1 - 0.00046 19.8 9.1 0.00046 19.8 6.3 2.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFM12802.1 - 0.0016 18.2 10.0 0.0038 17.0 4.5 3.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KFM12802.1 - 0.0032 17.5 9.1 0.0032 17.5 6.3 2.9 2 1 2 4 4 4 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KFM12802.1 - 0.0037 17.2 9.5 0.0037 17.2 6.6 3.9 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-CCHH PF10283.4 KFM12802.1 - 8.6 6.2 9.7 40 4.1 0.3 4.2 3 0 0 3 3 3 0 Zinc-finger (CX5CX6HX5H) motif Pkinase_Tyr PF07714.12 KFM12803.1 - 3.5e-64 216.3 0.0 4.6e-64 215.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM12803.1 - 2.7e-61 207.0 0.0 3.9e-61 206.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RBD PF02196.10 KFM12803.1 - 8.7e-30 102.2 0.3 2.3e-29 100.9 0.1 1.8 2 0 0 2 2 2 1 Raf-like Ras-binding domain C1_1 PF00130.17 KFM12803.1 - 7.2e-12 44.8 8.3 1.4e-11 43.8 5.7 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.1 KFM12803.1 - 6.2e-08 31.9 0.0 1.1e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like zf-RING-like PF08746.6 KFM12803.1 - 0.035 14.0 6.6 0.1 12.6 4.6 1.8 1 0 0 1 1 1 0 RING-like domain APH PF01636.18 KFM12803.1 - 0.16 11.6 0.0 0.81 9.3 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family C1_3 PF07649.7 KFM12803.1 - 0.55 10.3 7.0 1 9.4 4.9 1.5 1 0 0 1 1 1 0 C1-like domain zf-AN1 PF01428.11 KFM12803.1 - 5.3 6.9 10.5 5.1 7.0 5.6 2.2 2 0 0 2 2 2 0 AN1-like Zinc finger zf-CCHC PF00098.18 KFM12804.1 - 1e-52 173.6 62.2 5.3e-08 32.4 2.1 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 KFM12804.1 - 2.7e-14 52.5 52.0 0.0016 18.0 0.3 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_5 PF14787.1 KFM12804.1 - 3.5e-09 35.9 49.1 0.0036 16.7 1.8 6.8 4 1 3 7 7 7 6 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.1 KFM12804.1 - 5.1e-08 32.5 48.1 0.0023 17.6 0.2 7.1 2 1 5 7 7 7 6 Zinc knuckle zf-CCHC_6 PF15288.1 KFM12804.1 - 0.046 13.3 47.6 0.098 12.3 0.5 7.1 6 1 1 7 7 7 0 Zinc knuckle zf-CCHC_2 PF13696.1 KFM12804.1 - 0.45 10.0 0.1 0.45 10.0 0.1 7.1 3 2 4 7 7 7 0 Zinc knuckle Isy1 PF06246.7 KFM12805.1 - 9.9e-70 234.8 6.2 1.1e-69 234.6 4.3 1.0 1 0 0 1 1 1 1 Isy1-like splicing family BCAS3 PF12490.3 KFM12805.1 - 0.16 11.2 1.4 0.22 10.7 1.0 1.3 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 Hydrolase_6 PF13344.1 KFM12806.1 - 2.6e-22 78.6 0.0 4.9e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFM12806.1 - 7.6e-08 31.9 0.0 0.001 18.7 0.0 2.7 2 1 0 2 2 2 2 HAD-hyrolase-like Hydrolase PF00702.21 KFM12806.1 - 0.037 14.4 0.0 0.22 11.8 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase AviRa PF11599.3 KFM12806.1 - 0.14 11.2 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Ras PF00071.17 KFM12807.1 - 3.6e-36 123.9 0.1 4.5e-36 123.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM12807.1 - 4.7e-07 30.3 0.0 9.9e-07 29.2 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFM12807.1 - 1.3e-06 27.8 0.1 1.5e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFM12807.1 - 0.037 13.4 0.0 0.045 13.1 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain LRR_8 PF13855.1 KFM12808.1 - 5.8e-07 29.1 0.1 1.4e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Leucine rich repeat LRRNT PF01462.13 KFM12808.1 - 6.7e-07 28.6 9.0 9.2e-07 28.1 2.4 3.1 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_4 PF12799.2 KFM12808.1 - 6.3e-05 22.4 0.2 0.00021 20.8 0.1 1.9 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM12808.1 - 0.0054 16.5 1.8 0.055 13.5 0.1 3.2 4 0 0 4 4 4 1 Leucine Rich Repeat LRRCT PF01463.19 KFM12808.1 - 0.016 15.4 0.2 0.076 13.3 0.0 2.2 2 0 0 2 2 2 0 Leucine rich repeat C-terminal domain LRR_7 PF13504.1 KFM12808.1 - 0.18 12.1 0.6 2.3 8.8 0.1 2.9 2 0 0 2 2 2 0 Leucine rich repeat TFIIE-A_C-term PF11521.3 KFM12809.1 - 4.5e-33 113.0 4.9 4.5e-33 113.0 3.4 2.1 2 1 0 2 2 2 1 C-terminal general transcription factor TFIIE alpha TF_Zn_Ribbon PF08271.7 KFM12809.1 - 6.6e-05 22.1 0.1 0.00014 21.1 0.1 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding LLGL PF08366.8 KFM12810.1 - 2.6e-42 142.9 0.2 1.1e-41 140.9 0.0 2.1 2 0 0 2 2 2 1 LLGL2 WD40 PF00400.27 KFM12810.1 - 1.4e-11 43.8 0.3 0.046 13.6 0.0 6.2 5 1 0 5 5 5 3 WD domain, G-beta repeat Lgl_C PF08596.5 KFM12810.1 - 5.4e-06 25.1 0.0 9e-05 21.0 0.0 2.9 4 1 0 4 4 4 1 Lethal giant larvae(Lgl) like, C-terminal Synaptobrevin PF00957.16 KFM12810.1 - 0.00076 19.0 0.1 0.0018 17.8 0.0 1.5 1 0 0 1 1 1 1 Synaptobrevin Methyltransf_10 PF05971.7 KFM12811.1 - 1.2e-113 379.1 0.0 2.1e-113 378.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF890) MTS PF05175.9 KFM12811.1 - 0.00015 21.1 0.0 0.00032 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 KFM12811.1 - 0.00017 20.7 0.0 0.00037 19.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 KFM12811.1 - 0.0006 19.8 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MANEC PF07502.9 KFM12811.1 - 0.014 15.3 0.1 0.041 13.8 0.1 1.7 1 0 0 1 1 1 0 MANEC domain UPF0020 PF01170.13 KFM12811.1 - 0.039 13.5 0.0 0.075 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Death PF00531.17 KFM12812.1 - 4.9e-18 64.6 0.2 7.8e-18 64.0 0.1 1.3 1 0 0 1 1 1 1 Death domain TNFR_c6 PF00020.13 KFM12812.1 - 8.8e-15 54.4 51.5 6.6e-07 29.2 6.8 4.9 4 1 0 4 4 4 3 TNFR/NGFR cysteine-rich region DUF1391 PF07151.7 KFM12812.1 - 0.072 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1391) CTC1 PF15489.1 KFM12813.1 - 7.2e-37 126.3 0.5 7.9e-37 126.2 0.3 1.0 1 0 0 1 1 1 1 CST, telomere maintenance, complex subunit CTC1 DDRGK PF09756.4 KFM12813.1 - 0.043 13.2 0.0 0.059 12.7 0.0 1.1 1 0 0 1 1 1 0 DDRGK domain Ig_3 PF13927.1 KFM12814.1 - 1.9e-10 41.1 0.3 9e-05 22.9 0.1 2.4 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.12 KFM12814.1 - 1.4e-08 34.5 0.0 6.1e-07 29.3 0.0 2.4 2 1 0 2 2 2 1 Immunoglobulin V-set domain Ig_2 PF13895.1 KFM12814.1 - 7.8e-08 32.3 0.1 0.0028 17.7 0.0 2.4 1 1 1 2 2 2 2 Immunoglobulin domain I-set PF07679.11 KFM12814.1 - 3.1e-07 30.1 0.5 0.0012 18.6 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.20 KFM12814.1 - 0.0002 21.3 1.0 0.002 18.2 0.0 2.5 2 1 0 2 2 2 1 Immunoglobulin domain DUF1628 PF07790.6 KFM12814.1 - 0.13 13.0 1.0 0.41 11.4 0.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1628) EpuA PF11772.3 KFM12814.1 - 0.3 10.5 2.7 0.33 10.4 1.1 1.7 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta Filamin PF00630.14 KFM12815.1 - 2.8e-20 72.7 0.1 4.5e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Filamin/ABP280 repeat zf-B_box PF00643.19 KFM12815.1 - 3.4e-11 42.8 4.3 3.4e-11 42.8 3.0 4.1 5 0 0 5 5 5 2 B-box zinc finger SID-1_RNA_chan PF13965.1 KFM12817.1 - 5.7e-234 777.5 13.7 6.8e-234 777.3 9.5 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 HLH PF00010.21 KFM12819.1 - 1.9e-11 43.4 0.6 6.2e-11 41.8 0.4 2.0 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PhoU PF01895.14 KFM12819.1 - 0.53 10.7 0.8 1.2 9.6 0.6 1.6 1 0 0 1 1 1 0 PhoU domain Acetyltransf_1 PF00583.19 KFM12820.1 - 2.3e-16 59.5 0.0 3.3e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFM12820.1 - 3.6e-10 39.8 0.1 6.2e-10 39.0 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KFM12820.1 - 2.4e-07 30.8 0.1 2.6e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFM12820.1 - 3.2e-07 30.4 0.0 3.9e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KFM12820.1 - 2.7e-06 27.3 0.0 3.7e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFM12820.1 - 0.00011 22.0 0.0 0.00021 21.1 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFM12820.1 - 0.00017 21.2 0.0 0.00025 20.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 KFM12820.1 - 0.00069 19.7 0.0 0.00081 19.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Epsilon_antitox PF08998.6 KFM12820.1 - 0.016 15.1 0.1 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial epsilon antitoxin DUF3749 PF12568.3 KFM12820.1 - 0.059 12.9 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2206 PF09971.4 KFM12820.1 - 0.11 11.3 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) ATP-synt_ab PF00006.20 KFM12821.1 - 1.1e-111 371.5 0.0 1.6e-111 370.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KFM12821.1 - 2e-28 99.0 0.5 3.5e-28 98.3 0.3 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KFM12821.1 - 7.4e-14 51.7 2.0 2e-13 50.3 1.4 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_14 PF13173.1 KFM12821.1 - 0.053 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF1693 PF07984.7 KFM12823.1 - 7.4e-170 564.2 1.1 8.6e-170 563.9 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1693) Peptidase_U32 PF01136.14 KFM12823.1 - 0.12 11.2 0.0 0.23 10.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family U32 CRAL_TRIO_2 PF13716.1 KFM12824.1 - 2.8e-32 111.6 1.5 5.4e-32 110.7 1.1 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Macro PF01661.16 KFM12824.1 - 3.9e-26 91.2 0.0 7.4e-26 90.3 0.0 1.5 1 0 0 1 1 1 1 Macro domain CRAL_TRIO PF00650.15 KFM12824.1 - 5.1e-07 29.3 0.8 1.2e-06 28.1 0.5 1.6 1 0 0 1 1 1 1 CRAL/TRIO domain Epimerase_2 PF02350.14 KFM12824.1 - 0.11 11.2 0.0 0.19 10.4 0.0 1.3 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase WD40 PF00400.27 KFM12825.1 - 1.9e-78 255.7 13.8 2.6e-10 39.7 0.0 10.5 10 0 0 10 10 10 10 WD domain, G-beta repeat Utp12 PF04003.7 KFM12825.1 - 1.6e-24 85.8 0.2 1.6e-24 85.8 0.1 1.8 2 0 0 2 2 2 1 Dip2/Utp12 Family Nucleoporin_N PF08801.6 KFM12825.1 - 0.0086 14.8 2.6 2.2 6.9 0.0 4.2 3 2 0 5 5 5 2 Nup133 N terminal like Nup160 PF11715.3 KFM12825.1 - 0.3 9.1 6.3 4.8 5.1 0.0 4.2 3 2 1 4 4 4 0 Nucleoporin Nup120/160 PapD-like PF14874.1 KFM12826.1 - 4.9e-10 39.2 0.0 8.4e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Flagellar-associated PapD-like T-box PF00907.17 KFM12827.1 - 5e-86 286.8 0.1 6.9e-86 286.4 0.0 1.2 1 0 0 1 1 1 1 T-box tRNA-synt_1b PF00579.20 KFM12829.1 - 9e-68 228.5 0.0 1.1e-67 228.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Orthopox_A5L PF06193.6 KFM12829.1 - 0.11 12.4 0.1 0.25 11.2 0.1 1.6 1 1 0 1 1 1 0 Orthopoxvirus A5L protein-like FMN_dh PF01070.13 KFM12830.1 - 2e-131 438.1 0.2 6.9e-131 436.3 0.1 1.7 1 1 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 KFM12830.1 - 3.6e-07 29.4 0.4 1.4e-06 27.4 0.1 1.8 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KFM12830.1 - 1.7e-05 23.9 0.1 2.4e-05 23.4 0.1 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 KFM12830.1 - 0.00075 18.8 0.2 0.004 16.4 0.0 2.0 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.9 KFM12830.1 - 0.013 14.5 0.2 0.31 10.0 0.1 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DHO_dh PF01180.16 KFM12830.1 - 0.037 12.9 0.1 0.066 12.1 0.1 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase NMO PF03060.10 KFM12830.1 - 0.062 12.4 1.9 0.097 11.7 1.3 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase TMP-TENI PF02581.12 KFM12830.1 - 0.1 11.7 0.1 1.6 7.7 0.0 2.5 3 0 0 3 3 3 0 Thiamine monophosphate synthase/TENI Glyco_hydro_47 PF01532.15 KFM12831.1 - 4.6e-152 506.8 0.0 5.7e-152 506.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 OmpH PF03938.9 KFM12831.1 - 0.72 9.7 4.8 1.6 8.6 3.3 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ATP-synt_B PF00430.13 KFM12831.1 - 2.3 8.0 7.8 4.2 7.1 5.4 1.4 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) C2-set_2 PF08205.7 KFM12832.1 - 4.8e-07 29.5 0.6 1.4e-06 28.0 0.4 1.8 1 1 1 2 2 2 1 CD80-like C2-set immunoglobulin domain C1-set PF07654.10 KFM12832.1 - 0.00013 21.8 0.4 0.021 14.8 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin C1-set domain V-set PF07686.12 KFM12832.1 - 0.00073 19.4 0.7 0.05 13.4 0.1 2.2 2 0 0 2 2 2 2 Immunoglobulin V-set domain I-set PF07679.11 KFM12832.1 - 0.0053 16.5 0.1 0.32 10.8 0.0 2.7 2 1 1 3 3 3 1 Immunoglobulin I-set domain Ig_3 PF13927.1 KFM12832.1 - 0.019 15.4 2.7 0.05 14.1 1.2 2.3 2 1 0 2 2 2 0 Immunoglobulin domain ANF_receptor PF01094.23 KFM12833.1 - 3e-107 358.4 0.0 3.8e-107 358.1 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.17 KFM12833.1 - 3.6e-83 278.5 28.4 6.2e-83 277.7 19.7 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.9 KFM12833.1 - 2.7e-19 68.6 10.5 7.9e-19 67.1 7.3 1.9 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.1 KFM12833.1 - 3.1e-13 49.8 0.0 5.4e-12 45.7 0.0 2.5 2 1 0 2 2 2 1 Periplasmic binding protein GCC2_GCC3 PF07699.8 KFM12833.1 - 0.0068 15.9 4.5 0.014 14.9 2.5 1.9 1 1 0 1 1 1 1 GCC2 and GCC3 PIG-P PF08510.7 KFM12833.1 - 1.7 8.2 6.6 0.73 9.4 1.0 2.6 2 0 0 2 2 2 0 PIG-P Cystatin PF00031.16 KFM12834.1 - 8.9e-13 48.1 0.1 9.7e-13 48.0 0.1 1.0 1 0 0 1 1 1 1 Cystatin domain Cystatin PF00031.16 KFM12835.1 - 7.5e-13 48.4 0.1 8e-13 48.3 0.0 1.0 1 0 0 1 1 1 1 Cystatin domain DUF3828 PF12883.2 KFM12835.1 - 0.1 12.4 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3828) Cid2 PF09774.4 KFM12836.1 - 5.4e-26 91.5 4.8 9.4e-26 90.7 3.3 1.4 1 1 0 1 1 1 1 Caffeine-induced death protein 2 DUF837 PF05769.6 KFM12836.1 - 0.005 16.4 3.0 0.0072 15.8 2.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF837) GAS PF13851.1 KFM12836.1 - 0.0059 15.8 2.4 0.0069 15.6 1.7 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding TACC PF05010.9 KFM12836.1 - 0.043 13.5 6.4 0.066 12.9 4.5 1.3 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) Pil1 PF13805.1 KFM12836.1 - 0.09 11.9 1.9 0.11 11.6 1.3 1.1 1 0 0 1 1 1 0 Eisosome component PIL1 Mnd1 PF03962.10 KFM12836.1 - 0.3 10.7 6.0 0.46 10.1 4.2 1.3 1 1 0 1 1 1 0 Mnd1 family DUF1075 PF06388.6 KFM12837.1 - 1.5e-45 154.4 0.3 1.9e-45 154.0 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1075) Arm PF00514.18 KFM12839.1 - 3.1e-86 280.5 15.5 1.3e-13 50.2 0.0 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFM12839.1 - 6.3e-27 93.6 4.3 2.9e-08 33.8 0.0 5.6 2 1 6 8 8 7 7 HEAT repeats IBB PF01749.15 KFM12839.1 - 8.6e-27 93.1 8.0 1.8e-26 92.1 5.5 1.6 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 KFM12839.1 - 3.5e-16 59.1 4.9 2.5e-05 24.5 0.0 5.8 5 1 1 6 6 6 4 HEAT-like repeat HEAT PF02985.17 KFM12839.1 - 1.1e-10 40.6 9.8 0.00071 19.4 0.0 7.3 10 0 0 10 10 9 3 HEAT repeat RICTOR_V PF14668.1 KFM12839.1 - 1.8e-05 24.5 4.8 0.36 10.7 0.0 5.1 5 1 1 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 Arm_2 PF04826.8 KFM12839.1 - 2.1e-05 23.7 0.6 0.2 10.7 0.2 3.2 2 2 2 4 4 4 3 Armadillo-like V-ATPase_H_C PF11698.3 KFM12839.1 - 0.00014 21.7 0.3 0.18 11.7 0.0 4.3 2 1 3 5 5 5 2 V-ATPase subunit H Proteasom_PSMB PF10508.4 KFM12839.1 - 0.0078 14.5 1.5 0.021 13.0 0.2 2.0 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit TFCD_C PF12612.3 KFM12839.1 - 0.052 12.9 0.1 0.45 9.9 0.0 2.4 2 0 0 2 2 2 0 Tubulin folding cofactor D C terminal HEAT_PBS PF03130.11 KFM12839.1 - 1.8 9.2 7.9 8.7 7.1 0.2 5.0 6 1 0 6 6 5 0 PBS lyase HEAT-like repeat V-set PF07686.12 KFM12840.1 - 4e-17 62.1 0.1 4.9e-11 42.5 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin V-set domain C1-set PF07654.10 KFM12840.1 - 1.2e-14 54.1 0.1 3.6e-14 52.5 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.1 KFM12840.1 - 5.4e-14 52.4 7.1 5.2e-09 36.4 0.6 3.4 3 1 1 4 4 4 2 Immunoglobulin domain I-set PF07679.11 KFM12840.1 - 1.5e-09 37.6 0.0 0.00051 19.8 0.0 3.1 3 1 0 3 3 3 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM12840.1 - 5.5e-08 32.8 0.1 0.0073 16.4 0.0 2.7 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 KFM12840.1 - 1.6e-07 31.3 3.2 1.6e-05 24.9 0.0 3.0 2 1 0 2 2 2 1 Immunoglobulin domain C2-set_2 PF08205.7 KFM12840.1 - 0.0023 17.8 0.4 0.0095 15.8 0.1 2.2 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Cytomega_TRL10 PF06084.6 KFM12840.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein ASC PF00858.19 KFM12841.1 - 2.8e-110 368.9 8.9 3.4e-110 368.7 6.2 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel ComK PF06338.6 KFM12841.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 ComK protein Synaptobrevin PF00957.16 KFM12842.1 - 1.2e-34 117.7 3.1 1.3e-34 117.5 2.2 1.0 1 0 0 1 1 1 1 Synaptobrevin Med17 PF10156.4 KFM12842.1 - 0.0068 14.7 0.1 0.0082 14.4 0.0 1.0 1 0 0 1 1 1 1 Subunit 17 of Mediator complex DUF912 PF06024.7 KFM12842.1 - 0.12 12.4 0.3 0.14 12.1 0.2 1.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Gp_dh_C PF02800.15 KFM12843.1 - 1.9e-73 245.1 0.0 2.9e-73 244.4 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 KFM12843.1 - 1.9e-55 186.9 0.0 3.6e-55 186.0 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain OstA PF03968.9 KFM12843.1 - 0.077 12.9 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 OstA-like protein Filament PF00038.16 KFM12844.1 - 3.5e-14 52.9 26.5 8.3e-10 38.6 1.1 2.8 3 0 0 3 3 3 2 Intermediate filament protein Snapin_Pallidin PF14712.1 KFM12844.1 - 0.0052 17.0 2.6 0.0052 17.0 1.8 2.5 3 0 0 3 3 3 1 Snapin/Pallidin PAPA-1 PF04795.7 KFM12844.1 - 0.088 13.5 0.0 0.088 13.5 0.0 3.5 4 1 1 5 5 5 0 PAPA-1-like conserved region Sds3 PF08598.6 KFM12844.1 - 5.1 6.5 16.6 1.6 8.2 3.0 2.5 1 1 1 2 2 2 0 Sds3-like Nol1_Nop2_Fmu PF01189.12 KFM12845.1 - 3.8e-104 348.0 0.0 5e-104 347.6 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 KFM12845.1 - 1.4e-05 24.7 0.0 2.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KFM12845.1 - 0.00012 22.1 0.0 0.0002 21.4 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.14 KFM12845.1 - 0.0054 16.2 0.0 0.0087 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 KFM12845.1 - 0.0074 16.8 0.0 0.016 15.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 KFM12845.1 - 0.014 14.9 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_25 PF13649.1 KFM12845.1 - 0.13 12.6 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF1086 PF06461.6 KFM12846.1 - 5.9e-70 233.7 0.0 1.3e-69 232.6 0.0 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) CHDCT2 PF08074.6 KFM12846.1 - 2.3e-68 229.2 0.6 5e-68 228.1 0.4 1.6 1 0 0 1 1 1 1 CHDCT2 (NUC038) domain SNF2_N PF00176.18 KFM12846.1 - 8.3e-67 225.0 0.0 1.4e-66 224.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain CHDNT PF08073.7 KFM12846.1 - 2.4e-31 107.2 0.2 5.6e-31 105.9 0.1 1.7 1 0 0 1 1 1 1 CHDNT (NUC034) domain DUF1087 PF06465.8 KFM12846.1 - 1.7e-26 91.9 7.0 1.7e-26 91.9 4.9 2.5 2 0 0 2 2 1 1 Domain of Unknown Function (DUF1087) PHD PF00628.24 KFM12846.1 - 4.8e-22 77.4 28.0 4.4e-11 42.2 6.3 2.5 2 0 0 2 2 2 2 PHD-finger Chromo PF00385.19 KFM12846.1 - 1.2e-19 69.7 5.9 6.9e-13 48.0 0.5 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 KFM12846.1 - 9.6e-18 63.8 0.0 2.4e-17 62.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KFM12846.1 - 2.9e-10 39.4 0.0 1.1e-09 37.5 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 KFM12846.1 - 2.3e-06 27.5 0.7 1.3e-05 25.1 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PHD_2 PF13831.1 KFM12846.1 - 0.00014 21.1 11.2 0.024 13.9 1.9 2.7 2 0 0 2 2 2 2 PHD-finger AAA_22 PF13401.1 KFM12846.1 - 0.079 13.0 0.0 0.26 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain zf-PHD-like PF15446.1 KFM12846.1 - 0.1 11.8 10.1 0.72 9.1 0.6 3.0 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 KFM12846.1 - 0.86 9.3 18.4 0.31 10.8 0.8 3.1 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 KFM12846.1 - 3.6 7.3 19.5 2.3 8.0 2.8 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 7tm_1 PF00001.16 KFM12847.1 - 2.3e-51 174.4 22.4 2.7e-51 174.1 15.6 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3_C PF11970.3 KFM12847.1 - 0.059 13.1 2.4 0.18 11.5 0.2 2.9 2 1 1 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term DUF3302 PF11742.3 KFM12847.1 - 0.15 11.9 0.2 0.15 11.9 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3302) 60KD_IMP PF02096.15 KFM12847.1 - 4.4 6.9 8.9 0.42 10.2 1.0 2.3 2 0 0 2 2 2 0 60Kd inner membrane protein wnt PF00110.14 KFM12848.1 - 9.7e-120 399.4 20.8 1.1e-119 399.2 14.5 1.0 1 0 0 1 1 1 1 wnt family ING PF12998.2 KFM12849.1 - 3.4e-27 94.7 2.1 3.4e-27 94.7 1.5 2.0 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 KFM12849.1 - 4.8e-10 38.9 7.8 8.5e-10 38.1 5.4 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 KFM12849.1 - 0.016 15.2 0.5 0.038 14.1 0.4 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.1 KFM12849.1 - 0.02 14.1 1.3 0.035 13.4 0.9 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 KFM12849.1 - 0.037 14.0 5.2 0.064 13.2 3.6 1.4 1 0 0 1 1 1 0 RING-like domain ORF6C PF10552.4 KFM12849.1 - 1.1 9.0 6.9 2.9 7.6 1.3 2.2 2 0 0 2 2 2 0 ORF6C domain LMBR1 PF04791.11 KFM12849.1 - 5 5.5 5.9 5.7 5.4 3.2 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein DUF1192 PF06698.6 KFM12849.1 - 5.1 6.9 8.9 0.72 9.7 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) AJAP1_PANP_C PF15298.1 KFM12850.1 - 9.3e-58 195.4 0.0 1.2e-57 195.1 0.0 1.1 1 0 0 1 1 1 1 AJAP1/PANP C-terminus PCI PF01399.22 KFM12851.1 - 1.2e-11 44.8 0.3 5.4e-11 42.7 0.0 2.0 2 1 0 2 2 2 1 PCI domain Sipho_Gp157 PF05565.6 KFM12851.1 - 0.014 15.0 0.3 0.022 14.3 0.2 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 Rtf2 PF04641.7 KFM12851.1 - 0.049 12.8 2.6 0.065 12.4 1.8 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Mlf1IP PF10248.4 KFM12852.1 - 3.8e-76 254.6 7.3 4.8e-76 254.2 5.1 1.1 1 0 0 1 1 1 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein Ig_2 PF13895.1 KFM12854.1 - 3.4e-09 36.7 0.2 7.3e-07 29.2 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 KFM12854.1 - 7.1e-07 28.9 0.0 0.00055 19.7 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.20 KFM12854.1 - 7.5e-07 29.1 0.0 0.0028 17.7 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.12 KFM12854.1 - 1.4e-05 24.9 0.1 0.026 14.4 0.0 3.0 1 1 1 2 2 2 2 Immunoglobulin V-set domain Ig_3 PF13927.1 KFM12854.1 - 6.4e-05 23.3 0.5 0.071 13.6 0.4 2.3 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.12 KFM12855.1 - 1.5e-14 53.8 2.9 0.0054 16.6 0.0 4.4 4 0 0 4 4 4 3 Immunoglobulin V-set domain Ig_2 PF13895.1 KFM12855.1 - 1.4e-11 44.3 4.7 0.017 15.2 0.0 4.6 3 1 1 4 4 4 4 Immunoglobulin domain Tcell_CD4_Cterm PF12104.3 KFM12855.1 - 5.2e-10 38.7 9.5 9.8e-10 37.8 6.6 1.5 1 0 0 1 1 1 1 T cell CD4 receptor C terminal region ig PF00047.20 KFM12855.1 - 2.7e-07 30.5 1.2 0.32 11.1 0.0 4.4 4 1 0 4 4 4 3 Immunoglobulin domain Ig_3 PF13927.1 KFM12855.1 - 1.3e-06 28.7 2.1 5.6 7.5 0.0 4.9 3 2 1 4 4 4 2 Immunoglobulin domain I-set PF07679.11 KFM12855.1 - 3.4e-06 26.8 0.6 1.8 8.4 0.0 4.3 4 2 1 5 5 5 3 Immunoglobulin I-set domain C2-set PF05790.10 KFM12855.1 - 1.6e-05 24.8 2.5 0.66 9.9 0.1 4.9 4 1 0 4 4 4 2 Immunoglobulin C2-set domain V-set_CD47 PF08204.6 KFM12855.1 - 0.019 14.7 6.4 4.5 7.0 0.0 4.5 4 1 1 5 5 5 0 CD47 immunoglobulin-like domain PMP1_2 PF08114.6 KFM12855.1 - 0.021 14.3 1.9 0.037 13.5 1.3 1.4 1 0 0 1 1 1 0 ATPase proteolipid family CD4-extracel PF09191.5 KFM12855.1 - 0.063 13.2 0.2 0.14 12.1 0.2 1.6 1 0 0 1 1 1 0 CD4, extracellular Filamin PF00630.14 KFM12855.1 - 0.17 12.4 1.3 1.2 9.7 0.0 2.7 3 1 0 3 3 3 0 Filamin/ABP280 repeat 7tm_1 PF00001.16 KFM12856.1 - 2.6e-06 26.7 1.2 3.8e-06 26.2 0.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2062 PF09835.4 KFM12856.1 - 0.042 13.4 0.8 0.042 13.4 0.5 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) DUF1049 PF06305.6 KFM12856.1 - 0.063 12.7 0.1 0.17 11.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) WD40 PF00400.27 KFM12857.1 - 2.3e-54 179.4 26.3 3.1e-10 39.5 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KFM12857.1 - 9.8e-08 31.9 0.0 0.0086 15.8 0.0 3.0 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 KFM12857.1 - 0.0065 14.8 0.0 0.065 11.5 0.0 2.1 2 0 0 2 2 2 1 Cytochrome D1 heme domain UL11 PF11094.3 KFM12857.1 - 0.016 14.9 0.4 0.052 13.3 0.3 1.8 1 0 0 1 1 1 0 Membrane-associated tegument protein Pox_A_type_inc PF04508.7 KFM12857.1 - 0.047 13.4 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat TIM PF00121.13 KFM12858.1 - 3.7e-79 265.2 0.1 4.1e-79 265.1 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase LRR_4 PF12799.2 KFM12859.1 - 6.8e-24 83.0 23.6 4.6e-08 32.4 0.4 5.9 1 1 4 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM12859.1 - 1.4e-14 53.5 26.7 3.4e-06 26.6 2.2 5.1 2 1 5 7 7 7 6 Leucine rich repeat LRR_9 PF14580.1 KFM12859.1 - 1.8e-13 50.3 3.9 2.8e-12 46.5 0.4 2.6 1 1 2 3 3 3 1 Leucine-rich repeat LRR_1 PF00560.28 KFM12859.1 - 3.3e-10 38.5 20.2 0.094 12.8 0.2 7.9 6 3 1 7 7 7 4 Leucine Rich Repeat LRR_6 PF13516.1 KFM12859.1 - 0.00016 21.4 22.6 0.57 10.4 0.5 8.0 6 2 3 9 9 9 3 Leucine Rich repeat LRR_7 PF13504.1 KFM12859.1 - 0.014 15.4 32.1 3.7 8.1 0.3 8.7 10 1 1 11 11 11 0 Leucine rich repeat Enolase_C PF00113.17 KFM12860.1 - 2e-160 532.6 0.0 2.5e-160 532.2 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 KFM12860.1 - 4.6e-58 194.8 0.0 7.3e-58 194.1 0.0 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 KFM12860.1 - 1.9e-05 24.5 0.0 4.2e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.6 KFM12860.1 - 3.4e-05 22.8 0.3 7.5e-05 21.7 0.2 1.6 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 KFM12860.1 - 0.054 14.0 0.0 0.14 12.7 0.0 1.9 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain DUF4511 PF14974.1 KFM12861.1 - 1.3e-38 130.9 0.1 1.4e-38 130.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4511) FAST_2 PF08368.7 KFM12861.1 - 0.048 14.0 0.0 0.069 13.5 0.0 1.3 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 2 DUF4309 PF14172.1 KFM12861.1 - 0.12 12.2 0.0 3.1 7.7 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4309) Y_phosphatase PF00102.22 KFM12862.1 - 6.9e-79 264.4 0.2 1e-78 263.9 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase SH2 PF00017.19 KFM12862.1 - 2.3e-45 152.2 0.0 3.3e-21 74.8 0.0 2.8 2 0 0 2 2 2 2 SH2 domain DSPc PF00782.15 KFM12862.1 - 8.7e-06 25.3 0.1 2.8e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 KFM12862.1 - 0.0038 17.2 0.2 0.017 15.1 0.0 2.3 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 KFM12862.1 - 0.0054 16.9 0.6 0.031 14.5 0.0 2.6 4 0 0 4 4 4 1 Tyrosine phosphatase family Band_7 PF01145.20 KFM12863.1 - 2.4e-17 63.4 5.1 3.8e-17 62.7 3.5 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.3 KFM12863.1 - 0.00089 19.2 2.0 0.0017 18.3 1.4 1.4 1 0 0 1 1 1 1 Mediator complex subunit 2 ATP-synt_E PF05680.7 KFM12863.1 - 0.48 10.4 4.4 1 9.3 3.0 1.5 1 0 0 1 1 1 0 ATP synthase E chain MBOAT PF03062.14 KFM12864.1 - 9.4e-54 182.6 8.6 9.4e-54 182.6 6.0 2.5 2 1 1 3 3 3 2 MBOAT, membrane-bound O-acyltransferase family CUB PF00431.15 KFM12865.1 - 2.3e-19 69.5 0.0 3.9e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 CUB domain FXa_inhibition PF14670.1 KFM12865.1 - 9.2e-10 38.4 7.2 1.7e-09 37.6 5.0 1.5 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site EGF_CA PF07645.10 KFM12865.1 - 1.3e-05 25.0 9.2 2.4e-05 24.2 6.3 1.5 1 0 0 1 1 1 1 Calcium-binding EGF domain EGF PF00008.22 KFM12865.1 - 0.00013 21.7 8.3 0.00026 20.8 5.8 1.5 1 0 0 1 1 1 1 EGF-like domain CUB_2 PF02408.15 KFM12865.1 - 0.074 12.6 1.3 0.23 10.9 0.2 2.2 2 1 1 3 3 3 0 CUB-like domain CUB PF00431.15 KFM12866.1 - 8.2e-51 170.7 0.1 8e-27 93.5 0.0 2.4 2 0 0 2 2 2 2 CUB domain Trypsin PF00089.21 KFM12866.1 - 1.2e-49 168.8 0.0 1.8e-49 168.3 0.0 1.3 1 0 0 1 1 1 1 Trypsin Sushi PF00084.15 KFM12866.1 - 1e-15 57.7 18.6 2.1e-10 40.7 0.3 3.8 3 0 0 3 3 3 2 Sushi domain (SCR repeat) FXa_inhibition PF14670.1 KFM12866.1 - 1.2e-09 38.1 12.8 3.7e-09 36.5 6.8 2.9 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site cEGF PF12662.2 KFM12866.1 - 0.00011 21.7 6.5 0.00077 19.0 2.6 3.1 2 0 0 2 2 2 1 Complement Clr-like EGF-like EGF_CA PF07645.10 KFM12866.1 - 0.00071 19.5 11.5 0.0012 18.7 6.8 2.5 2 0 0 2 2 2 1 Calcium-binding EGF domain CUB_2 PF02408.15 KFM12866.1 - 0.0019 17.7 0.1 0.3 10.6 0.0 2.8 3 0 0 3 3 3 1 CUB-like domain EGF PF00008.22 KFM12866.1 - 0.0025 17.7 7.1 0.012 15.5 5.0 2.3 1 0 0 1 1 1 1 EGF-like domain Peptidase_S6 PF02395.11 KFM12866.1 - 0.02 13.0 0.1 0.029 12.5 0.1 1.1 1 0 0 1 1 1 0 Immunoglobulin A1 protease Lipocalin_7 PF14651.1 KFM12867.1 - 0.017 14.8 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family Cadherin PF00028.12 KFM12868.1 - 1e-12 48.1 0.0 1.9e-06 28.0 0.0 2.7 3 0 0 3 3 3 2 Cadherin domain Laminin_G_3 PF13385.1 KFM12868.1 - 5e-08 33.3 0.0 1.6e-07 31.6 0.0 1.9 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Mito_carr PF00153.22 KFM12869.1 - 1.9e-66 219.8 0.0 1.9e-22 78.7 0.1 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein TPR_11 PF13414.1 KFM12870.1 - 9e-26 89.3 5.1 1.6e-12 46.8 0.1 4.5 2 2 2 5 5 5 4 TPR repeat TPR_1 PF00515.23 KFM12870.1 - 3.7e-23 80.1 1.9 1.9e-05 24.0 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 KFM12870.1 - 2.4e-18 64.4 6.1 0.00014 21.4 0.3 6.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 KFM12870.1 - 1.5e-16 60.5 11.7 4.9e-07 30.2 0.4 5.5 4 2 2 6 6 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 KFM12870.1 - 1.6e-16 59.0 0.6 0.029 14.5 0.0 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFM12870.1 - 1.3e-14 53.3 14.3 0.0096 16.4 0.2 7.8 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.1 KFM12870.1 - 5.2e-12 45.5 3.8 1.3e-06 28.2 0.9 4.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFM12870.1 - 1.6e-10 40.0 0.1 0.33 10.8 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFM12870.1 - 2.1e-10 39.6 0.8 0.11 12.2 0.0 5.9 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFM12870.1 - 2.6e-10 40.4 3.5 0.015 15.6 0.0 4.7 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.1 KFM12870.1 - 7.7e-08 32.3 0.1 0.11 12.6 0.0 4.8 2 2 2 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 KFM12870.1 - 1.1e-07 31.8 0.7 0.0039 17.2 0.0 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 KFM12870.1 - 3.9e-06 26.5 3.0 0.23 11.4 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 KFM12870.1 - 9.9e-06 25.3 7.0 0.042 13.7 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFM12870.1 - 0.018 15.5 10.4 3.7 8.2 0.1 6.5 8 0 0 8 8 6 0 Tetratricopeptide repeat DUF1641 PF07849.6 KFM12870.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) Secretin_N_2 PF07655.8 KFM12870.1 - 0.16 12.4 0.1 0.38 11.1 0.0 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain 7tm_4 PF13853.1 KFM12871.1 - 3.4e-38 130.6 13.0 3.4e-38 130.6 9.0 3.2 2 1 1 3 3 3 1 Olfactory receptor 7tm_1 PF00001.16 KFM12871.1 - 5.2e-22 78.2 21.6 5.2e-22 78.2 14.9 1.3 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) NTPase_P4 PF11602.3 KFM12871.1 - 0.021 13.8 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 Pkinase_Tyr PF07714.12 KFM12872.1 - 4e-96 321.0 0.0 6.3e-96 320.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ephrin_lbd PF01404.14 KFM12872.1 - 5.4e-57 192.4 1.0 8e-57 191.8 0.7 1.3 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase PF00069.20 KFM12872.1 - 5.7e-48 163.3 0.0 8.3e-48 162.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.16 KFM12872.1 - 2e-23 82.3 0.0 6.5e-11 42.2 0.0 2.7 3 0 0 3 3 2 2 Fibronectin type III domain SAM_1 PF00536.25 KFM12872.1 - 2.2e-22 79.0 0.0 4.6e-22 77.9 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFM12872.1 - 5.2e-18 64.6 0.0 1.1e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EphA2_TM PF14575.1 KFM12872.1 - 4e-12 46.3 0.0 7.9e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain GCC2_GCC3 PF07699.8 KFM12872.1 - 2.7e-05 23.6 2.5 2.7e-05 23.6 1.7 3.4 2 1 1 3 3 3 1 GCC2 and GCC3 Tissue_fac PF01108.12 KFM12872.1 - 0.002 17.8 0.0 0.12 12.1 0.0 2.4 2 0 0 2 2 2 1 Tissue factor SusE PF14292.1 KFM12872.1 - 0.039 13.7 0.0 0.21 11.4 0.0 2.0 2 0 0 2 2 2 0 SusE outer membrane protein Reeler PF02014.11 KFM12872.1 - 0.073 13.3 0.1 20 5.4 0.0 3.0 3 0 0 3 3 3 0 Reeler domain Kdo PF06293.9 KFM12872.1 - 0.14 11.2 0.0 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NCD3G PF07562.9 KFM12872.1 - 4.8 6.9 12.3 0.14 11.8 2.0 3.0 2 1 1 3 3 3 0 Nine Cysteines Domain of family 3 GPCR cEGF PF12662.2 KFM12872.1 - 7.4 6.3 14.2 0.49 10.0 0.8 3.7 3 1 0 3 3 3 0 Complement Clr-like EGF-like LIM PF00412.17 KFM12873.1 - 1.3e-33 114.8 33.7 1.1e-12 47.8 5.8 3.2 3 0 0 3 3 3 3 LIM domain FAM131 PF15010.1 KFM12874.1 - 2.5e-119 398.4 15.8 5e-119 397.4 11.0 1.4 1 1 0 1 1 1 1 Putative cell signalling Peptidase_C14 PF00656.17 KFM12875.1 - 7.9e-38 130.5 1.1 8.8e-38 130.4 0.2 1.5 2 0 0 2 2 2 1 Caspase domain CARD PF00619.16 KFM12875.1 - 2.7e-19 68.7 0.6 7e-19 67.4 0.4 1.7 1 0 0 1 1 1 1 Caspase recruitment domain TMEM51 PF15345.1 KFM12876.1 - 0.28 10.8 2.3 0.32 10.6 1.5 1.3 1 1 0 1 1 1 0 Transmembrane protein 51 Rap_GAP PF02145.10 KFM12877.1 - 6.3e-62 208.3 0.0 9.3e-62 207.7 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP GoLoco PF02188.12 KFM12877.1 - 0.00018 20.7 1.3 0.00037 19.7 0.9 1.6 1 0 0 1 1 1 1 GoLoco motif DSBA PF01323.15 KFM12878.1 - 2.3e-45 154.5 0.0 2.6e-45 154.3 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain EAL PF00563.15 KFM12878.1 - 0.019 14.4 0.2 0.066 12.6 0.0 1.9 2 0 0 2 2 2 0 EAL domain Ras PF00071.17 KFM12879.1 - 2.7e-50 169.9 0.1 3.2e-50 169.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM12879.1 - 1.1e-22 80.7 0.2 2e-22 79.8 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFM12879.1 - 4.5e-07 29.2 0.0 6.5e-07 28.7 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family ArgK PF03308.11 KFM12879.1 - 0.00027 19.7 1.0 0.049 12.4 0.3 2.1 2 0 0 2 2 2 2 ArgK protein SRPRB PF09439.5 KFM12879.1 - 0.0016 17.7 0.9 0.0056 15.9 0.7 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KFM12879.1 - 0.0041 17.0 0.0 0.0062 16.4 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_32 PF13654.1 KFM12879.1 - 0.018 13.7 1.7 0.78 8.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KFM12879.1 - 0.021 14.9 0.2 0.18 11.9 0.1 2.5 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 KFM12879.1 - 0.053 12.7 1.4 0.11 11.7 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 KFM12879.1 - 0.075 12.6 0.0 0.23 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KFM12879.1 - 0.08 12.6 1.0 0.19 11.4 0.7 1.9 1 1 0 1 1 1 0 Archaeal ATPase AAA_28 PF13521.1 KFM12879.1 - 0.09 12.7 0.1 0.18 11.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain DUF2408 PF10303.4 KFM12879.1 - 0.22 11.6 5.2 5.3 7.1 3.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2408) Pkinase_Tyr PF07714.12 KFM12880.1 - 5.5e-89 297.6 0.2 8.1e-89 297.1 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM12880.1 - 6.8e-49 166.3 0.0 1.1e-48 165.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 KFM12880.1 - 8.3e-42 140.8 0.5 3.4e-21 74.8 0.0 2.5 2 0 0 2 2 2 2 SH2 domain Kdo PF06293.9 KFM12880.1 - 0.0012 17.9 0.1 0.0021 17.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KFM12880.1 - 0.061 12.2 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.17 KFM12880.1 - 0.11 11.8 0.4 0.21 10.9 0.3 1.4 1 0 0 1 1 1 0 RIO1 family p25-alpha PF05517.7 KFM12881.1 - 1.4e-54 184.5 4.1 1.6e-54 184.3 2.8 1.0 1 0 0 1 1 1 1 p25-alpha RNA_pol_Rpb1_5 PF04998.12 KFM12881.1 - 0.0069 15.6 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 EF-hand_1 PF00036.27 KFM12881.1 - 0.071 12.4 0.5 0.83 9.1 0.0 2.8 3 0 0 3 3 3 0 EF hand ECH PF00378.15 KFM12882.1 - 9.5e-60 201.7 2.5 1.1e-59 201.5 1.7 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Vert_IL3-reg_TF PF06529.6 KFM12883.1 - 3.7e-214 709.8 18.8 5.3e-214 709.3 13.0 1.2 1 0 0 1 1 1 1 Vertebrate interleukin-3 regulated transcription factor bZIP_2 PF07716.10 KFM12883.1 - 1.6e-14 53.4 9.3 1.6e-14 53.4 6.4 2.9 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.16 KFM12883.1 - 3e-05 23.8 6.5 3e-05 23.8 4.5 3.6 3 0 0 3 3 3 1 bZIP transcription factor HALZ PF02183.13 KFM12883.1 - 0.72 9.6 3.7 4 7.2 0.6 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper IncA PF04156.9 KFM12883.1 - 8.7 5.8 10.3 2.1 7.8 3.7 2.6 2 1 0 2 2 2 0 IncA protein Pkinase_Tyr PF07714.12 KFM12884.1 - 8.6e-87 290.4 0.0 1.1e-86 290.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM12884.1 - 2.5e-40 138.2 0.0 3.6e-40 137.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kringle PF00051.13 KFM12884.1 - 1.4e-25 89.1 2.2 8.1e-25 86.7 1.6 2.2 2 0 0 2 2 2 1 Kringle domain Fz PF01392.17 KFM12884.1 - 8e-24 84.2 4.3 3.1e-23 82.3 3.0 2.1 1 0 0 1 1 1 1 Fz domain I-set PF07679.11 KFM12884.1 - 4.8e-18 64.7 0.0 9.2e-18 63.8 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM12884.1 - 3.7e-09 36.5 1.1 1.5e-08 34.6 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.12 KFM12884.1 - 5.4e-07 29.5 0.2 4e-06 26.7 0.1 2.3 1 1 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 KFM12884.1 - 7.2e-07 29.2 0.0 2.1e-06 27.7 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFM12884.1 - 2.1e-06 28.1 0.0 8.1e-06 26.2 0.0 2.1 1 0 0 1 1 1 1 Immunoglobulin domain TMEM154 PF15102.1 KFM12884.1 - 0.0029 17.3 0.1 0.0092 15.6 0.0 1.8 1 0 0 1 1 1 1 TMEM154 protein family DUF2149 PF09919.4 KFM12884.1 - 0.1 12.7 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) I-set PF07679.11 KFM12885.1 - 7.1e-20 70.6 0.0 7.6e-20 70.5 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM12885.1 - 1.3e-10 41.2 0.0 1.5e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFM12885.1 - 2.6e-09 36.9 0.4 4.5e-08 32.9 0.3 2.0 1 1 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 KFM12885.1 - 1.6e-08 34.5 0.0 3.6e-08 33.3 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFM12885.1 - 3e-08 34.0 0.2 1e-07 32.3 0.1 1.7 1 1 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.7 KFM12885.1 - 0.0044 16.8 0.1 0.0068 16.2 0.1 1.5 1 1 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Aminotran_1_2 PF00155.16 KFM12886.1 - 1.8e-42 145.5 0.0 2.1e-42 145.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II PAD PF03068.10 KFM12886.1 - 0.0045 15.4 0.0 0.0064 14.9 0.0 1.1 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) Cys_Met_Meta_PP PF01053.15 KFM12886.1 - 0.076 11.2 0.0 0.12 10.6 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme PBD PF00786.23 KFM12887.1 - 1.1e-05 25.7 1.1 1.3e-05 25.5 0.8 1.4 1 1 0 1 1 1 1 P21-Rho-binding domain HIT PF01230.18 KFM12888.1 - 9.1e-25 87.0 0.0 1e-24 86.9 0.0 1.0 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KFM12888.1 - 1.6e-17 63.7 0.0 1.8e-17 63.5 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding UQ_con PF00179.21 KFM12889.1 - 3.9e-10 39.3 0.0 1.6e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFM12889.1 - 0.002 17.8 0.0 0.0049 16.6 0.0 1.7 2 0 0 2 2 2 1 Prokaryotic E2 family B RWD PF05773.17 KFM12889.1 - 0.027 14.3 0.0 2.9 7.8 0.0 2.3 2 0 0 2 2 2 0 RWD domain RNA_pol_Rpb2_4 PF04566.8 KFM12889.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 4 KIAA1430 PF13879.1 KFM12889.1 - 0.27 11.7 2.1 16 6.0 0.1 2.6 3 0 0 3 3 3 0 KIAA1430 homologue A_deamin PF02137.13 KFM12890.1 - 2.3e-104 349.4 0.1 3.9e-104 348.6 0.0 1.4 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain z-alpha PF02295.12 KFM12890.1 - 5.3e-41 138.2 0.2 3.6e-20 71.4 0.0 2.7 2 0 0 2 2 2 2 Adenosine deaminase z-alpha domain dsrm PF00035.20 KFM12890.1 - 1.1e-38 131.5 2.0 7.2e-13 48.9 0.0 3.9 4 0 0 4 4 4 3 Double-stranded RNA binding motif DND1_DSRM PF14709.1 KFM12890.1 - 1.1e-07 32.0 0.1 0.37 11.1 0.0 4.2 3 1 0 3 3 3 3 double strand RNA binding domain from DEAD END PROTEIN 1 TrmB PF01978.14 KFM12890.1 - 0.00024 20.7 0.0 0.52 10.0 0.0 2.8 3 0 0 3 3 3 2 Sugar-specific transcriptional regulator TrmB HTH_15 PF12324.3 KFM12890.1 - 0.021 14.4 0.1 0.42 10.3 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase IF2_N PF04760.10 KFM12890.1 - 0.031 13.9 0.1 0.1 12.2 0.0 1.9 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region TFIIE_alpha PF02002.12 KFM12890.1 - 0.072 12.5 0.0 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 TFIIE alpha subunit P-mevalo_kinase PF04275.9 KFM12891.1 - 6.4e-39 132.2 0.0 9.5e-39 131.7 0.0 1.2 1 0 0 1 1 1 1 Phosphomevalonate kinase DUF3670 PF12419.3 KFM12891.1 - 0.0096 15.3 0.1 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 SNF2 Helicase protein P63C PF10546.4 KFM12891.1 - 0.097 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 P63C domain PHD PF00628.24 KFM12892.1 - 4.6e-08 32.6 6.0 6.5e-08 32.1 4.2 1.2 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 KFM12892.1 - 0.0002 21.0 2.8 0.0002 21.0 2.0 1.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 PHD_2 PF13831.1 KFM12892.1 - 0.047 12.9 0.7 0.51 9.7 0.5 2.2 1 1 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.1 KFM12892.1 - 0.061 13.1 4.6 0.12 12.2 3.3 1.5 1 1 0 1 1 1 0 Ring finger domain PID PF00640.18 KFM12893.1 - 1.5e-45 154.5 0.0 2.3e-45 154.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SH2 PF00017.19 KFM12893.1 - 3.5e-18 65.1 0.0 6e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 SH2 domain DUF4581 PF15167.1 KFM12893.1 - 0.12 12.2 0.1 0.42 10.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4581) PAPS_reduct PF01507.14 KFM12894.1 - 3.2e-31 108.4 0.0 4.4e-21 75.4 0.0 2.2 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family MoCF_biosynth PF00994.19 KFM12894.1 - 5.6e-23 80.9 0.0 1.1e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 Probable molybdopterin binding domain DC_STAMP PF07782.8 KFM12895.1 - 2.9e-52 177.0 0.0 6.7e-52 175.8 0.0 1.7 1 0 0 1 1 1 1 DC-STAMP-like protein ATP-synt_B PF00430.13 KFM12895.1 - 0.016 14.9 0.2 0.036 13.8 0.1 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DC_STAMP PF07782.8 KFM12896.1 - 5.5e-42 143.5 2.8 5.5e-42 143.5 1.9 3.0 2 2 0 2 2 2 1 DC-STAMP-like protein Reprolysin PF01421.14 KFM12897.1 - 2.2e-59 200.4 0.0 2.8e-59 200.0 0.0 1.1 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Disintegrin PF00200.18 KFM12897.1 - 7.5e-17 61.3 10.1 7.5e-17 61.3 7.0 1.8 2 0 0 2 2 2 1 Disintegrin Reprolysin_5 PF13688.1 KFM12897.1 - 2e-15 57.2 0.0 2e-15 57.2 0.0 1.4 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KFM12897.1 - 5.5e-12 46.2 0.0 7.4e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFM12897.1 - 3.5e-09 36.9 0.0 4.8e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFM12897.1 - 7.4e-08 32.1 0.1 1.8e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 KFM12897.1 - 0.029 13.7 0.0 0.039 13.2 0.0 1.2 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M10 PF00413.19 KFM12897.1 - 0.03 14.0 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 Matrixin MtN3_slv PF03083.11 KFM12898.1 - 6.9e-21 73.9 0.6 1e-20 73.3 0.4 1.3 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.9 KFM12898.1 - 0.0023 17.4 1.6 0.003 17.0 0.1 1.9 2 0 0 2 2 2 1 PQ loop repeat Lung_7-TM_R PF06814.8 KFM12898.1 - 0.078 11.9 1.3 0.092 11.6 0.9 1.0 1 0 0 1 1 1 0 Lung seven transmembrane receptor 7TM-7TMR_HD PF07698.6 KFM12898.1 - 0.082 12.3 4.4 0.1 12.0 3.0 1.1 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase RasGAP PF00616.14 KFM12899.1 - 1.6e-34 119.2 0.1 4.6e-34 117.8 0.1 1.8 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase VPS9 PF02204.13 KFM12899.1 - 5.9e-29 100.1 0.0 1.8e-28 98.5 0.0 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Motilin_assoc PF04643.7 KFM12899.1 - 0.11 12.0 3.1 14 5.2 0.0 3.6 3 0 0 3 3 3 0 Motilin/ghrelin-associated peptide Latrophilin PF02354.11 KFM12901.1 - 9.8e-182 603.5 12.9 1.4e-181 603.1 8.9 1.2 1 0 0 1 1 1 1 Latrophilin Cytoplasmic C-terminal region OLF PF02191.11 KFM12901.1 - 3.9e-95 317.8 3.2 6.5e-95 317.1 2.3 1.4 1 0 0 1 1 1 1 Olfactomedin-like domain DUF3497 PF12003.3 KFM12901.1 - 4.6e-72 241.9 0.9 6.8e-72 241.3 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3497) 7tm_2 PF00002.19 KFM12901.1 - 2.3e-67 226.6 17.4 3.5e-67 226.0 12.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Gal_Lectin PF02140.13 KFM12901.1 - 1.2e-23 83.1 0.9 3.5e-23 81.7 0.6 1.8 1 0 0 1 1 1 1 Galactose binding lectin domain GPS PF01825.16 KFM12901.1 - 9.5e-16 57.6 7.1 2.2e-15 56.4 4.9 1.7 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain HRM PF02793.17 KFM12901.1 - 9.1e-09 35.2 1.5 2.6e-08 33.7 1.0 1.9 1 0 0 1 1 1 1 Hormone receptor domain DUF2602 PF10782.4 KFM12901.1 - 0.39 10.5 6.1 0.89 9.4 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2602) 7tm_2 PF00002.19 KFM12903.1 - 1.7e-56 191.0 27.6 2.8e-56 190.3 19.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF3497 PF12003.3 KFM12903.1 - 9.4e-40 136.2 3.5 1.3e-39 135.8 2.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3497) GPS PF01825.16 KFM12903.1 - 1e-15 57.5 5.7 1e-15 57.5 3.9 2.1 2 0 0 2 2 2 1 Latrophilin/CL-1-like GPS domain EGF_CA PF07645.10 KFM12903.1 - 1.3e-15 57.0 46.5 2.1e-08 34.0 7.0 3.8 3 1 0 3 3 3 3 Calcium-binding EGF domain cEGF PF12662.2 KFM12903.1 - 2.3e-11 43.1 19.9 2e-07 30.5 0.4 3.8 3 0 0 3 3 3 2 Complement Clr-like EGF-like EGF_3 PF12947.2 KFM12903.1 - 8.7e-11 41.6 55.2 1.2e-05 25.1 5.3 5.0 5 0 0 5 5 5 3 EGF domain EGF PF00008.22 KFM12903.1 - 3.3e-05 23.7 49.1 0.002 18.0 6.7 5.0 4 1 0 4 4 4 3 EGF-like domain FXa_inhibition PF14670.1 KFM12903.1 - 0.0018 18.3 8.2 0.0018 18.3 5.7 4.4 4 0 0 4 4 4 2 Coagulation Factor Xa inhibitory site Vitellogenin_N PF01347.17 KFM12904.1 - 2.2e-150 501.8 2.0 2.2e-150 501.8 1.4 2.1 2 0 0 2 2 2 1 Lipoprotein amino terminal region DUF1943 PF09172.6 KFM12904.1 - 1.7e-69 234.0 0.3 1.7e-69 234.0 0.2 2.7 2 1 1 3 3 3 1 Domain of unknown function (DUF1943) DUF1944 PF09175.5 KFM12904.1 - 2.5e-53 180.0 0.8 2.5e-53 180.0 0.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1944) VWD PF00094.20 KFM12904.1 - 8.3e-26 91.0 1.2 8.3e-26 91.0 0.8 2.6 2 0 0 2 2 2 1 von Willebrand factor type D domain HEAT_2 PF13646.1 KFM12904.1 - 0.00042 20.5 0.3 0.01 16.0 0.0 3.3 3 1 0 3 3 3 1 HEAT repeats 7tm_1 PF00001.16 KFM12905.1 - 1.9e-25 89.4 17.2 1.9e-25 89.4 11.9 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Serpentine_r_xa PF03383.10 KFM12905.1 - 6.2e-05 22.7 4.0 6.2e-05 22.7 2.8 3.0 1 1 1 3 3 3 1 Caenorhabditis serpentine receptor-like protein, class xa Prominin PF05478.6 KFM12905.1 - 0.0093 13.5 4.2 0.016 12.7 2.9 1.3 1 0 0 1 1 1 1 Prominin CopD PF05425.8 KFM12905.1 - 1.4 9.1 7.2 1.3 9.3 1.3 3.0 1 1 2 3 3 3 0 Copper resistance protein D SdpI PF13630.1 KFM12905.1 - 5 6.8 22.3 4.9 6.9 1.9 3.9 2 2 1 3 3 3 0 SdpI/YhfL protein family BatA PF07584.6 KFM12905.1 - 5.1 7.3 11.1 11 6.2 1.0 3.7 4 0 0 4 4 4 0 Aerotolerance regulator N-terminal PDZ PF00595.19 KFM12906.1 - 1.8e-08 34.4 0.0 3e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM12906.1 - 0.056 13.3 0.0 0.14 12.0 0.0 1.6 2 0 0 2 2 2 0 PDZ domain DUF3294 PF07957.6 KFM12906.1 - 0.11 12.0 0.3 0.17 11.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) PDZ PF00595.19 KFM12907.1 - 4.7e-09 36.3 0.0 6.4e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM12907.1 - 0.02 14.8 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 PDZ domain DnaJ PF00226.26 KFM12908.1 - 1.7e-29 101.3 3.4 2.7e-29 100.7 2.3 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KFM12908.1 - 4.4e-24 84.1 1.0 5e-21 74.4 0.0 2.8 3 0 0 3 3 3 2 DnaJ C terminal domain KH_1 PF00013.24 KFM12909.1 - 1.4e-60 200.7 15.1 9.7e-18 63.5 0.0 4.5 4 1 0 4 4 4 4 KH domain KH_3 PF13014.1 KFM12909.1 - 1.6e-35 120.1 24.1 2.4e-11 43.0 0.5 5.1 4 1 0 4 4 4 4 KH domain KH_2 PF07650.12 KFM12909.1 - 3.1e-19 68.2 9.7 1.2e-05 24.7 0.2 4.3 4 0 0 4 4 4 4 KH domain DUF1897 PF09005.5 KFM12909.1 - 4.3e-16 58.0 26.1 6.2e-10 38.3 7.1 3.6 3 0 0 3 3 3 3 Domain of unknown function (DUF1897) KH_4 PF13083.1 KFM12909.1 - 3.8e-06 26.4 7.9 0.057 13.0 0.1 4.3 4 0 0 4 4 4 2 KH domain Secretin_N PF03958.12 KFM12909.1 - 0.00053 20.1 0.4 0.066 13.4 0.2 3.3 3 1 1 4 4 4 1 Bacterial type II/III secretion system short domain KH_5 PF13184.1 KFM12909.1 - 0.0048 16.6 4.3 1.7 8.5 0.0 3.5 3 0 0 3 3 3 2 NusA-like KH domain I-set PF07679.11 KFM12910.1 - 2.1e-18 65.9 0.0 6.4e-18 64.4 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM12910.1 - 2.2e-05 24.4 0.0 4.3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFM12910.1 - 0.00067 19.7 0.1 0.0019 18.2 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain DUF2217 PF10265.4 KFM12911.1 - 4.8e-224 744.9 4.6 5.4e-224 744.7 3.2 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2217) UCH PF00443.24 KFM12912.1 - 2.1e-69 233.6 0.0 1.3e-67 227.7 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFM12912.1 - 1.7e-28 99.9 0.0 1.6e-27 96.7 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 KFM12912.1 - 7.4e-23 80.8 0.4 2.8e-13 50.0 0.0 3.6 3 0 0 3 3 3 2 DUSP domain zf-UBP PF02148.14 KFM12912.1 - 1.7e-11 44.0 4.9 1.7e-11 44.0 3.4 3.6 5 0 0 5 5 5 1 Zn-finger in ubiquitin-hydrolases and other protein Lar_restr_allev PF14354.1 KFM12912.1 - 0.27 11.5 4.1 42 4.5 0.1 4.2 4 0 0 4 4 4 0 Restriction alleviation protein Lar Myb_DNA-binding PF00249.26 KFM12914.1 - 5e-10 39.2 0.2 1.1e-09 38.1 0.2 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFM12914.1 - 5.6e-07 29.5 0.1 1.9e-06 27.8 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 KFM12914.1 - 3.9e-05 23.1 7.4 3.9e-05 23.1 5.2 2.3 2 0 0 2 2 2 1 Zinc finger, ZZ type ADK PF00406.17 KFM12915.1 - 7.6e-75 249.8 0.0 4.6e-38 130.4 0.0 2.2 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.1 KFM12915.1 - 1.3e-21 77.6 0.1 8.8e-10 39.4 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KFM12915.1 - 6.5e-19 68.5 0.1 6.6e-08 32.9 0.0 3.4 2 1 1 3 3 3 2 AAA domain AAA_33 PF13671.1 KFM12915.1 - 9.8e-13 48.1 0.0 3.6e-05 23.6 0.0 3.0 2 2 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KFM12915.1 - 5.1e-07 28.9 0.1 0.012 14.6 0.1 2.7 2 1 0 2 2 2 2 Zeta toxin Thymidylate_kin PF02223.12 KFM12915.1 - 3.7e-06 26.4 3.3 0.062 12.6 0.0 4.1 4 0 0 4 4 4 2 Thymidylate kinase AAA_19 PF13245.1 KFM12915.1 - 0.00022 20.8 0.1 0.15 11.7 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA PF00004.24 KFM12915.1 - 0.00035 20.7 0.1 0.44 10.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFM12915.1 - 0.00037 20.6 0.1 0.91 9.6 0.0 3.1 2 1 0 3 3 3 2 AAA domain AAA_28 PF13521.1 KFM12915.1 - 0.00056 19.9 0.2 0.81 9.6 0.0 2.6 2 1 0 2 2 2 2 AAA domain Cytidylate_kin2 PF13189.1 KFM12915.1 - 0.0012 18.8 0.1 2 8.2 0.0 2.7 2 0 0 2 2 2 2 Cytidylate kinase-like family dNK PF01712.14 KFM12915.1 - 0.0021 17.9 0.1 0.38 10.6 0.0 2.6 2 0 0 2 2 2 1 Deoxynucleoside kinase AAA_16 PF13191.1 KFM12915.1 - 0.005 16.8 0.1 1.8 8.5 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain SKI PF01202.17 KFM12915.1 - 0.011 15.5 0.3 38 4.1 0.0 3.8 4 0 0 4 4 4 0 Shikimate kinase SRP54 PF00448.17 KFM12915.1 - 0.028 13.8 0.7 6.9 6.0 0.0 2.8 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain CobU PF02283.11 KFM12915.1 - 0.031 13.6 0.6 3.2 7.1 0.0 3.1 4 1 0 4 4 4 0 Cobinamide kinase / cobinamide phosphate guanyltransferase DUF2075 PF09848.4 KFM12915.1 - 0.04 12.9 0.1 4.5 6.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 KFM12915.1 - 0.054 12.5 0.5 6 5.9 0.0 2.7 3 0 0 3 3 3 0 KaiC Peptidase_C13 PF01650.13 KFM12916.1 - 1.3e-43 149.1 0.0 1.7e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family Glyco_transf_29 PF00777.13 KFM12917.1 - 3.5e-39 134.5 0.1 4e-39 134.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) YcfA PF07927.7 KFM12917.1 - 3.8 7.4 4.9 21 5.0 3.4 2.1 1 1 0 1 1 1 0 YcfA-like protein FAM183 PF14886.1 KFM12918.1 - 1e-30 106.4 0.6 1.2e-30 106.2 0.4 1.0 1 0 0 1 1 1 1 FAM183A and FAM183B related LLC1 PF14945.1 KFM12918.1 - 0.011 15.9 0.1 0.014 15.6 0.1 1.1 1 0 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Ebp2 PF05890.7 KFM12919.1 - 6.7e-85 284.6 27.6 7.7e-85 284.4 19.1 1.0 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 V_ATPase_I PF01496.14 KFM12919.1 - 0.16 9.8 8.4 0.2 9.4 5.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family WXG100 PF06013.7 KFM12919.1 - 0.22 11.5 4.5 0.96 9.4 0.6 2.7 2 0 0 2 2 2 0 Proteins of 100 residues with WXG GvpL_GvpF PF06386.6 KFM12919.1 - 0.52 9.8 10.0 0.06 12.9 3.8 1.8 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF LTXXQ PF07813.7 KFM12919.1 - 0.54 10.7 15.1 0.11 12.9 7.8 1.8 2 0 0 2 2 2 0 LTXXQ motif family protein DUF342 PF03961.8 KFM12919.1 - 0.86 7.9 11.0 1.2 7.5 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) PEP-utilisers_N PF05524.8 KFM12919.1 - 2.2 8.0 8.7 18 5.1 0.9 3.1 1 1 2 3 3 3 0 PEP-utilising enzyme, N-terminal Peptidase_M55 PF04951.8 KFM12919.1 - 5 6.2 6.0 6.1 5.9 0.0 2.1 1 1 1 2 2 2 0 D-aminopeptidase DUF4407 PF14362.1 KFM12919.1 - 5.3 5.9 11.6 7.9 5.3 8.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) WD40 PF00400.27 KFM12920.1 - 1e-15 56.8 13.8 3.7e-05 23.4 0.0 5.9 7 0 0 7 7 7 3 WD domain, G-beta repeat Reo_sigmaC PF04582.7 KFM12920.1 - 0.00015 21.0 5.6 0.059 12.5 0.3 4.1 2 1 1 4 4 4 2 Reovirus sigma C capsid protein AAA_13 PF13166.1 KFM12920.1 - 0.0013 17.2 40.5 0.0013 17.2 28.1 3.1 1 1 2 3 3 3 1 AAA domain ADIP PF11559.3 KFM12920.1 - 0.0061 16.4 11.6 0.0061 16.4 8.0 5.7 3 1 3 6 6 6 2 Afadin- and alpha -actinin-Binding TMEM125 PF15109.1 KFM12921.1 - 1.7e-58 195.6 8.5 1.7e-58 195.6 5.9 2.0 2 0 0 2 2 2 1 TMEM125 protein family NfeD PF01957.13 KFM12921.1 - 0.1 12.7 9.7 0.15 12.2 0.9 2.1 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding IncA PF04156.9 KFM12921.1 - 0.15 11.6 22.7 0.29 10.7 3.4 2.2 2 0 0 2 2 2 0 IncA protein DUF4234 PF14018.1 KFM12921.1 - 0.28 10.9 0.2 0.28 10.9 0.1 3.0 1 1 0 2 2 1 0 Domain of unknown function (DUF4234) Serpentine_r_xa PF03383.10 KFM12921.1 - 0.54 10.0 4.4 0.35 10.6 1.2 2.1 1 1 2 3 3 3 0 Caenorhabditis serpentine receptor-like protein, class xa Claudin_2 PF13903.1 KFM12921.1 - 0.56 9.8 19.7 1.3 8.6 6.5 2.1 1 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF898 PF05987.8 KFM12921.1 - 0.7 8.7 5.0 0.36 9.6 0.7 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) CopD PF05425.8 KFM12921.1 - 1.8 8.8 12.1 0.24 11.6 1.2 2.2 2 0 0 2 2 2 0 Copper resistance protein D DUF4013 PF13197.1 KFM12921.1 - 4.6 6.5 15.8 2 7.7 3.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4013) PgaD PF13994.1 KFM12921.1 - 5.7 6.4 6.0 0.71 9.3 0.9 1.9 3 0 0 3 3 3 0 PgaD-like protein zf-DHHC PF01529.15 KFM12921.1 - 9.9 5.5 7.1 33 3.7 4.9 1.9 1 1 0 1 1 1 0 DHHC palmitoyltransferase LRR19-TM PF15176.1 KFM12922.1 - 4.9e-37 125.7 0.0 8e-37 125.0 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat family 19 TM domain LRR_8 PF13855.1 KFM12922.1 - 5.8e-32 109.2 44.4 6e-12 45.1 4.6 2.8 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.2 KFM12922.1 - 2.9e-12 45.8 13.1 6e-06 25.7 0.1 3.4 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM12922.1 - 4.2e-08 32.1 14.5 0.45 10.7 0.5 5.7 5 0 0 5 5 5 4 Leucine Rich Repeat LRRCT PF01463.19 KFM12922.1 - 0.00053 20.0 0.1 0.003 17.6 0.1 2.4 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain LRR_9 PF14580.1 KFM12922.1 - 0.0038 16.7 0.1 0.0061 16.1 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_7 PF13504.1 KFM12922.1 - 0.018 15.1 16.2 19 6.0 0.3 5.6 5 0 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 KFM12922.1 - 0.029 14.4 18.6 1.9 8.8 0.1 5.4 4 1 1 5 5 5 0 Leucine Rich repeat AJAP1_PANP_C PF15298.1 KFM12922.1 - 0.032 14.1 0.0 0.047 13.5 0.0 1.2 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Pkinase_Tyr PF07714.12 KFM12923.1 - 5.7e-78 261.5 0.0 8.5e-78 260.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM12923.1 - 8e-42 143.1 0.0 2.7e-41 141.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain fn3 PF00041.16 KFM12923.1 - 3e-29 100.9 0.8 1.9e-13 50.3 0.4 3.7 4 0 0 4 4 4 3 Fibronectin type III domain hEGF PF12661.2 KFM12923.1 - 4.6e-09 35.7 40.9 0.0028 17.6 2.4 5.1 4 0 0 4 4 4 4 Human growth factor-like EGF I-set PF07679.11 KFM12923.1 - 1.2e-08 34.6 0.1 0.0073 16.1 0.0 2.8 3 0 0 3 3 3 2 Immunoglobulin I-set domain Laminin_EGF PF00053.19 KFM12923.1 - 0.028 14.3 47.6 2.6 8.0 14.0 3.8 1 1 2 3 3 3 0 Laminin EGF-like (Domains III and V) V-set PF07686.12 KFM12923.1 - 0.038 13.8 0.1 6.7 6.6 0.0 2.9 2 1 0 2 2 2 0 Immunoglobulin V-set domain APH PF01636.18 KFM12923.1 - 0.26 11.0 0.0 0.71 9.5 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family EGF_2 PF07974.8 KFM12923.1 - 0.28 11.3 65.3 0.074 13.2 10.6 5.2 4 1 0 4 4 4 0 EGF-like domain EpoR_lig-bind PF09067.5 KFM12924.1 - 3.5e-32 110.4 1.0 6.7e-30 103.1 0.2 2.7 3 0 0 3 3 3 2 Erythropoietin receptor, ligand binding fn3 PF00041.16 KFM12924.1 - 1.7e-16 60.1 1.9 4.7e-09 36.2 0.1 3.6 4 0 0 4 4 4 3 Fibronectin type III domain IL6Ra-bind PF09240.5 KFM12924.1 - 5e-11 42.6 2.3 5.6e-05 23.2 0.3 2.6 2 0 0 2 2 2 2 Interleukin-6 receptor alpha chain, binding Tissue_fac PF01108.12 KFM12924.1 - 7.9e-05 22.3 1.5 0.0006 19.5 0.0 3.0 4 0 0 4 4 4 1 Tissue factor WD40 PF00400.27 KFM12925.1 - 9.4e-38 126.7 14.3 3.8e-09 36.0 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KFM12925.1 - 0.067 11.3 4.7 11 4.0 0.1 3.5 2 2 1 3 3 3 0 Nucleoporin Nup120/160 TFIIIC_delta PF12657.2 KFM12925.1 - 0.079 12.6 4.0 0.25 11.0 0.5 3.1 2 2 0 2 2 2 0 Transcription factor IIIC subunit delta N-term ELO PF01151.13 KFM12926.1 - 1.2e-63 214.7 22.6 1.5e-63 214.4 15.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Med8 PF10232.4 KFM12927.1 - 1.5e-69 233.9 0.4 1.9e-69 233.6 0.3 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Baculo_PEP_C PF04513.7 KFM12927.1 - 0.055 13.2 0.3 11 5.8 0.2 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sigma70_r4 PF04545.11 KFM12930.1 - 0.11 11.7 0.1 5.4 6.4 0.0 2.7 3 0 0 3 3 3 0 Sigma-70, region 4 AP_endonuc_2 PF01261.19 KFM12931.1 - 2.6e-21 75.8 0.0 4e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Y_phosphatase PF00102.22 KFM12932.1 - 9.4e-173 571.6 1.5 4.2e-89 297.9 0.1 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.16 KFM12932.1 - 6.2e-111 362.7 30.2 1.9e-16 59.9 0.2 8.9 8 0 0 8 8 8 8 Fibronectin type III domain I-set PF07679.11 KFM12932.1 - 5e-44 148.0 0.0 4e-16 58.6 0.0 4.1 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM12932.1 - 1.2e-23 83.0 0.0 7e-08 32.4 0.0 4.2 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 KFM12932.1 - 2.2e-19 69.6 2.5 0.00056 20.3 0.0 6.9 7 0 0 7 7 7 3 Immunoglobulin domain Interfer-bind PF09294.5 KFM12932.1 - 4e-16 58.9 0.2 0.023 14.7 0.0 7.5 8 0 0 8 8 8 3 Interferon-alpha/beta receptor, fibronectin type III ig PF00047.20 KFM12932.1 - 1.7e-11 44.0 0.0 0.016 15.3 0.0 4.5 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 KFM12932.1 - 1.1e-08 34.9 0.1 0.025 14.4 0.0 4.7 4 1 0 4 4 3 2 Immunoglobulin V-set domain DSPc PF00782.15 KFM12932.1 - 1.2e-08 34.6 0.0 0.0026 17.3 0.0 2.5 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFM12932.1 - 2e-07 31.4 0.0 0.069 13.3 0.0 3.2 3 0 0 3 3 3 2 Tyrosine phosphatase family C2-set_2 PF08205.7 KFM12932.1 - 3.4e-07 30.0 3.3 0.095 12.6 0.0 4.7 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain PTPlike_phytase PF14566.1 KFM12932.1 - 2.6e-06 27.5 0.1 0.0061 16.6 0.0 2.8 2 0 0 2 2 2 2 Inositol hexakisphosphate Y_Y_Y PF07495.8 KFM12932.1 - 2.6e-05 23.8 0.8 0.025 14.3 0.0 3.5 3 0 0 3 3 3 1 Y_Y_Y domain TMEM154 PF15102.1 KFM12932.1 - 0.00078 19.1 0.0 0.00078 19.1 0.0 1.9 2 0 0 2 2 1 1 TMEM154 protein family DUF2369 PF10179.4 KFM12932.1 - 0.02 14.0 0.2 27 3.7 0.0 4.2 3 1 2 5 5 5 0 Uncharacterised conserved protein (DUF2369) ICAM_N PF03921.9 KFM12932.1 - 0.087 12.3 0.0 0.38 10.2 0.0 2.2 1 0 0 1 1 1 0 Intercellular adhesion molecule (ICAM), N-terminal domain YhjQ PF06564.7 KFM12932.1 - 0.29 10.4 0.0 0.61 9.4 0.0 1.4 1 0 0 1 1 1 0 YhjQ protein JmjC PF02373.17 KFM12933.1 - 1e-43 148.1 0.1 2.8e-43 146.7 0.1 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.1 KFM12933.1 - 3.4e-33 113.9 9.2 3.4e-33 113.9 6.4 3.0 3 0 0 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KFM12933.1 - 1.9e-15 56.7 6.1 1.9e-15 56.7 4.2 3.6 2 1 1 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.1 KFM12933.1 - 4e-13 48.4 8.3 4e-13 48.4 5.8 3.3 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 KFM12933.1 - 2.2e-06 27.2 28.8 2.7e-06 26.9 3.8 4.3 4 0 0 4 4 4 2 PHD-finger LBR_tudor PF09465.5 KFM12933.1 - 0.00014 21.4 0.6 0.0052 16.3 0.1 2.5 2 0 0 2 2 2 1 Lamin-B receptor of TUDOR domain DUF4537 PF15057.1 KFM12933.1 - 0.01 15.5 0.2 0.029 14.1 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4537) 53-BP1_Tudor PF09038.5 KFM12933.1 - 0.058 13.2 0.2 0.45 10.3 0.2 2.2 1 1 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor Hex_IIIa PF02455.11 KFM12933.1 - 1.9 7.0 5.6 2.8 6.5 3.9 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Glyco_transf_29 PF00777.13 KFM12934.1 - 1e-72 244.5 0.0 1.3e-72 244.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Xpo1 PF08389.7 KFM12935.1 - 4.4e-28 98.0 9.6 2.4e-24 85.9 0.3 4.4 4 1 0 4 4 4 3 Exportin 1-like protein IBN_N PF03810.14 KFM12935.1 - 7.8e-07 28.9 3.1 1e-06 28.5 0.3 2.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain Diphthamide_syn PF01866.12 KFM12936.1 - 9.8e-70 235.2 0.0 1.2e-69 234.9 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein ATP-synt_C PF00137.16 KFM12937.1 - 1.6e-29 101.6 29.1 4.6e-16 58.4 5.8 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Glyco_transf_7N PF13733.1 KFM12938.1 - 7.9e-47 158.0 0.1 1.2e-46 157.4 0.1 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.9 KFM12938.1 - 7.4e-31 105.4 1.0 1.7e-30 104.2 0.7 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFM12938.1 - 3.4e-07 29.6 0.2 0.00022 20.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 SNF PF00209.13 KFM12939.1 - 2.3e-144 481.7 21.8 2.6e-144 481.5 15.1 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Caveolin PF01146.12 KFM12939.1 - 0.27 10.8 4.9 0.55 9.8 3.4 1.5 1 0 0 1 1 1 0 Caveolin zf-C2H2 PF00096.21 KFM12940.1 - 4.9e-12 45.4 12.3 4.8e-06 26.6 3.0 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM12940.1 - 1.6e-09 37.3 13.0 0.00011 22.3 2.4 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFM12940.1 - 1.5e-07 31.3 5.0 1.5e-07 31.3 3.4 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-BED PF02892.10 KFM12940.1 - 0.031 14.0 3.9 0.3 10.8 1.8 2.2 1 1 1 2 2 2 0 BED zinc finger Zn_Tnp_IS1 PF03811.8 KFM12940.1 - 0.049 13.1 2.2 0.049 13.1 1.5 1.5 2 0 0 2 2 2 0 InsA N-terminal domain zf-C2H2_2 PF12756.2 KFM12940.1 - 0.13 12.4 2.4 0.11 12.5 0.9 1.5 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 KFM12940.1 - 0.13 11.9 2.4 1.5 8.5 0.3 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.1 KFM12940.1 - 0.6 10.4 0.1 0.6 10.4 0.1 2.7 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-met PF12874.2 KFM12940.1 - 0.66 10.2 3.4 0.54 10.5 0.7 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DMAP1 PF05499.7 KFM12941.1 - 5.1e-81 270.4 6.8 8.3e-81 269.7 4.7 1.3 1 0 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) DUF498 PF04430.9 KFM12941.1 - 0.078 12.5 0.0 0.27 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF498/DUF598) Atg14 PF10186.4 KFM12941.1 - 0.16 10.9 10.2 0.43 9.4 6.5 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 RNase_T PF00929.19 KFM12943.1 - 5.6e-38 130.8 0.0 6.6e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Exonuclease zf-C3HC4_2 PF13923.1 KFM12944.1 - 1.3e-06 28.3 10.2 1.6e-06 28.0 4.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM12944.1 - 0.0045 16.7 9.5 0.0071 16.1 3.9 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KFM12944.1 - 0.0093 15.6 5.3 0.0093 15.6 3.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM12944.1 - 0.033 13.8 6.9 0.081 12.6 2.4 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pox_A_type_inc PF04508.7 KFM12944.1 - 0.19 11.5 4.8 0.18 11.6 0.6 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat zf-RING_5 PF14634.1 KFM12944.1 - 0.29 10.9 8.7 0.21 11.3 2.8 2.4 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFM12944.1 - 1.9 8.4 10.4 0.39 10.6 2.8 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-MIZ PF02891.15 KFM12944.1 - 2 8.0 9.9 0.34 10.4 2.5 2.2 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger DUF829 PF05705.9 KFM12945.1 - 3.1e-62 210.3 0.1 3.5e-62 210.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.2 KFM12945.1 - 0.0016 18.3 0.1 0.002 18.0 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Drf_GBD PF06371.8 KFM12946.1 - 0.018 14.3 0.3 0.1 11.9 0.0 2.2 2 1 0 2 2 2 0 Diaphanous GTPase-binding Domain HEAT_2 PF13646.1 KFM12946.1 - 0.077 13.2 3.5 0.56 10.5 1.5 2.7 2 1 0 2 2 2 0 HEAT repeats Kinesin PF00225.18 KFM12947.1 - 5.4e-95 317.9 0.1 5.4e-95 317.9 0.1 1.9 2 0 0 2 2 2 1 Kinesin motor domain Ribosomal_S8e PF01201.17 KFM12948.1 - 1.5e-48 164.2 1.5 1.8e-48 164.0 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e SMAP PF15477.1 KFM12948.1 - 0.054 13.7 0.3 0.11 12.8 0.2 1.5 1 0 0 1 1 1 0 Small acidic protein family Bestrophin PF01062.16 KFM12949.1 - 2.6e-98 328.5 4.8 3e-98 328.3 3.3 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Pkinase PF00069.20 KFM12950.1 - 1.5e-67 227.4 0.0 2.7e-67 226.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain POLO_box PF00659.13 KFM12950.1 - 9.3e-37 124.8 1.9 2.5e-17 62.5 0.1 2.5 2 0 0 2 2 2 2 POLO box duplicated region Pkinase_Tyr PF07714.12 KFM12950.1 - 1e-33 116.5 0.0 1.5e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM12950.1 - 6.3e-09 35.2 0.0 1e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFM12950.1 - 0.031 14.0 0.2 4.8 6.8 0.1 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Tctex-1 PF03645.8 KFM12951.1 - 5.7e-21 74.2 0.0 6.4e-21 74.1 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family Patched PF02460.13 KFM12952.1 - 6.9e-71 239.2 9.6 7.5e-43 146.5 0.0 2.1 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.3 KFM12952.1 - 3.1e-49 166.3 6.8 3.1e-49 166.3 4.7 2.7 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 KFM12952.1 - 8.6e-05 21.3 4.6 8.6e-05 21.3 3.2 2.5 2 1 0 2 2 2 1 MMPL family MENTAL PF10457.4 KFM12952.1 - 0.027 14.1 1.2 2.4 7.7 0.6 2.4 2 0 0 2 2 2 0 Cholesterol-capturing domain NTP_transferase PF00483.18 KFM12953.1 - 3e-14 52.9 0.0 4.9e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 KFM12953.1 - 1.8e-11 44.3 0.0 2.7e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.19 KFM12953.1 - 0.00016 21.0 10.7 0.16 11.5 1.1 3.7 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) HECT PF00632.20 KFM12954.1 - 1.1e-51 175.9 0.0 1.4e-51 175.5 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HECT PF00632.20 KFM12956.1 - 3.8e-54 183.9 0.0 5.5e-54 183.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) APC10 PF03256.11 KFM12956.1 - 9.8e-12 44.8 0.0 2.2e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.20 KFM12956.1 - 0.001 18.9 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain URO-D PF01208.12 KFM12957.1 - 6.5e-128 426.4 0.0 7.4e-128 426.2 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) SWIM PF04434.12 KFM12958.1 - 0.027 13.9 1.9 0.075 12.5 1.3 1.8 1 0 0 1 1 1 0 SWIM zinc finger SelP_N PF04592.9 KFM12959.1 - 5.2e-26 91.4 1.0 5.6e-26 91.3 0.7 1.0 1 0 0 1 1 1 1 Selenoprotein P, N terminal region Ribosomal_L37e PF01907.14 KFM12959.1 - 0.096 12.5 0.1 0.81 9.5 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein L37e Glyoxalase PF00903.20 KFM12960.1 - 1.1e-10 41.5 0.0 1.6e-08 34.5 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 KFM12960.1 - 2.1e-09 37.3 0.0 2.2e-05 24.3 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KFM12960.1 - 2.2e-09 37.8 0.0 0.0034 17.9 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.1 KFM12960.1 - 0.0039 17.1 0.0 17 5.2 0.0 3.2 3 0 0 3 3 3 2 Glyoxalase-like domain HhH-GPD PF00730.20 KFM12961.1 - 1.8e-22 79.6 0.0 3e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.1 KFM12961.1 - 6.1e-17 61.0 0.0 1.5e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 NUDIX domain HHH PF00633.18 KFM12961.1 - 1.3e-05 24.5 0.0 5.3e-05 22.6 0.0 2.1 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.4 KFM12961.1 - 0.019 15.1 5.4 0.019 15.1 3.7 2.4 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III CAF1 PF04857.15 KFM12962.1 - 7.9e-44 149.9 0.0 1.2e-43 149.3 0.0 1.3 1 0 0 1 1 1 1 CAF1 family ribonuclease zf-CCCH PF00642.19 KFM12962.1 - 0.00011 21.8 0.1 0.00011 21.8 0.1 2.2 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pkinase_Tyr PF07714.12 KFM12963.1 - 1.6e-41 142.0 0.0 2.1e-41 141.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM12963.1 - 1.2e-39 135.9 0.0 1.5e-39 135.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KFM12963.1 - 0.00058 18.9 0.0 0.0009 18.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family AhpC-TSA PF00578.16 KFM12966.1 - 1.7e-42 144.0 0.0 2.7e-42 143.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KFM12966.1 - 1.6e-16 60.1 0.0 2.2e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 KFM12966.1 - 1e-15 57.1 0.0 1.8e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Aldo_ket_red PF00248.16 KFM12967.1 - 6.6e-60 202.3 0.0 7.6e-60 202.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SHNi-TPR PF10516.4 KFM12968.1 - 2.5e-15 55.3 5.7 1.1e-14 53.4 0.9 2.9 3 0 0 3 3 3 1 SHNi-TPR TPR_12 PF13424.1 KFM12968.1 - 6.9e-09 35.5 16.1 9.5e-07 28.6 4.2 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFM12968.1 - 8.5e-09 34.6 10.6 0.016 15.0 0.2 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 KFM12968.1 - 1.2e-08 34.4 12.3 8.9e-06 25.2 3.2 3.5 2 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KFM12968.1 - 1.6e-08 33.7 5.3 0.014 14.9 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFM12968.1 - 0.00017 21.8 4.5 0.022 15.3 0.1 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFM12968.1 - 0.0003 21.3 11.1 0.2 12.3 0.1 3.8 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFM12968.1 - 0.00054 19.5 6.8 3.7 7.5 0.2 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFM12968.1 - 0.088 13.3 6.6 5.7 7.6 0.0 4.8 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFM12968.1 - 0.41 10.5 3.4 14 5.8 0.3 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat Vasculin PF15337.1 KFM12970.1 - 5.9e-44 148.4 3.7 1.6e-43 147.0 2.6 1.8 1 0 0 1 1 1 1 Vascular protein family Vasculin-like 1 DUF3429 PF11911.3 KFM12971.1 - 4.4e-33 114.2 7.8 5.7e-33 113.8 5.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Kelch_1 PF01344.20 KFM12972.1 - 6.8e-78 256.0 15.4 1.1e-14 53.6 0.2 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 KFM12972.1 - 8.5e-50 164.9 3.2 9.4e-10 38.2 0.0 6.3 1 1 5 6 6 6 6 Kelch motif BACK PF07707.10 KFM12972.1 - 8.5e-31 105.8 0.8 2.1e-30 104.5 0.3 1.8 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_4 PF13418.1 KFM12972.1 - 3e-28 97.3 3.9 5.8e-05 22.7 0.0 6.6 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.1 KFM12972.1 - 7.8e-28 95.9 4.5 4.9e-06 26.5 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.10 KFM12972.1 - 5.2e-24 83.0 9.7 8e-07 28.5 0.0 6.7 6 1 0 6 6 6 4 Kelch motif BTB PF00651.26 KFM12972.1 - 7.5e-24 83.8 0.0 1.5e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_5 PF13854.1 KFM12972.1 - 2.9e-12 46.2 7.3 0.029 14.3 0.0 6.3 6 0 0 6 6 6 4 Kelch motif DUF3342 PF11822.3 KFM12972.1 - 0.0009 18.4 0.0 0.012 14.7 0.0 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF3342) She2p PF11435.3 KFM12972.1 - 0.059 12.7 0.7 0.52 9.6 0.2 2.1 1 1 1 2 2 2 0 RNA binding protein She2p Folate_rec PF03024.9 KFM12973.1 - 4.8e-51 172.6 25.7 4.8e-51 172.6 17.8 1.4 2 0 0 2 2 2 1 Folate receptor family DUF1908 PF08926.6 KFM12975.1 - 1.1e-148 493.4 0.3 1.1e-148 493.4 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1908) Pkinase PF00069.20 KFM12975.1 - 8.9e-65 218.4 0.0 1.7e-64 217.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM12975.1 - 5.1e-27 94.5 0.0 9.6e-27 93.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PDZ PF00595.19 KFM12975.1 - 5.5e-09 36.0 0.0 1.2e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM12975.1 - 4.1e-07 29.7 0.0 9.8e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Kinase-like PF14531.1 KFM12975.1 - 3.6e-05 22.8 0.2 0.00035 19.6 0.0 2.3 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 KFM12975.1 - 0.00048 19.9 0.0 0.053 13.2 0.0 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Tricorn_PDZ PF14685.1 KFM12975.1 - 0.023 14.4 0.0 0.057 13.2 0.0 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain RIO1 PF01163.17 KFM12975.1 - 0.026 13.8 0.1 0.026 13.8 0.0 2.0 2 0 0 2 2 2 0 RIO1 family SH2 PF00017.19 KFM12976.1 - 4.4e-41 138.5 0.0 2.1e-19 69.0 0.0 2.6 2 0 0 2 2 2 2 SH2 domain RhoGAP PF00620.22 KFM12976.1 - 5.6e-14 52.0 0.7 2.7e-13 49.7 0.0 2.3 2 1 0 2 2 2 1 RhoGAP domain SH3_1 PF00018.23 KFM12976.1 - 5.9e-06 25.5 0.2 0.0007 18.9 0.0 2.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KFM12976.1 - 4.2e-05 23.0 0.1 0.00014 21.3 0.1 2.0 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFM12976.1 - 0.0004 19.8 0.0 0.001 18.5 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain DUF1338 PF07063.8 KFM12976.1 - 0.019 14.0 1.4 0.03 13.3 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1338) ATG11 PF10377.4 KFM12976.1 - 0.03 14.2 0.1 0.03 14.2 0.0 1.9 2 0 0 2 2 2 0 Autophagy-related protein 11 IncA PF04156.9 KFM12976.1 - 0.064 12.8 11.8 0.13 11.8 8.2 1.5 1 0 0 1 1 1 0 IncA protein Zeta_toxin PF06414.7 KFM12976.1 - 0.16 11.0 4.1 0.28 10.2 2.9 1.3 1 0 0 1 1 1 0 Zeta toxin Tetraspannin PF00335.15 KFM12977.1 - 3.4e-39 134.3 12.5 4.6e-39 133.9 8.6 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF872 PF05915.7 KFM12977.1 - 0.089 12.6 5.2 0.21 11.4 3.6 1.7 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) DUF3098 PF11297.3 KFM12977.1 - 1.2 8.9 6.0 7.1 6.4 4.1 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3098) DUF2207 PF09972.4 KFM12977.1 - 1.3 7.5 3.5 1.7 7.1 2.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Kinocilin PF15033.1 KFM12977.1 - 2 7.9 8.1 0.52 9.8 0.2 2.6 2 1 1 3 3 3 0 Kinocilin protein TMEM171 PF15471.1 KFM12977.1 - 2.2 6.9 5.7 3.6 6.3 4.0 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 SUR7 PF06687.7 KFM12977.1 - 2.3 7.7 17.5 0.11 12.0 8.3 1.5 2 0 0 2 2 2 0 SUR7/PalI family GNT-I PF03071.10 KFM12978.1 - 1.5e-51 175.2 0.2 3e-51 174.3 0.1 1.4 1 0 0 1 1 1 1 GNT-I family MGAT2 PF05060.9 KFM12978.1 - 0.044 12.6 0.0 0.18 10.7 0.0 1.9 2 0 0 2 2 2 0 N-acetylglucosaminyltransferase II (MGAT2) LURAP PF14854.1 KFM12979.1 - 3.4e-47 159.1 3.1 4.5e-47 158.7 2.1 1.1 1 0 0 1 1 1 1 Leucine rich adaptor protein SNF2_N PF00176.18 KFM12980.1 - 2.5e-66 223.5 0.0 4.4e-66 222.6 0.0 1.4 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFM12980.1 - 2.1e-13 49.9 0.0 4.1e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFM12980.1 - 3.2e-09 36.5 0.0 1.3e-08 34.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 KFM12980.1 - 1.2e-08 34.1 0.1 3e-08 32.8 0.0 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Rad54_N PF08658.5 KFM12980.1 - 4.9e-05 23.1 0.0 0.00074 19.3 0.0 2.4 2 0 0 2 2 2 1 Rad54 N terminal ResIII PF04851.10 KFM12980.1 - 8.8e-05 22.4 0.0 0.00039 20.2 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 KFM12980.1 - 0.11 11.5 0.0 0.33 9.8 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) LRR_6 PF13516.1 KFM12981.1 - 0.11 12.6 13.4 2.6 8.3 0.1 5.7 6 0 0 6 6 6 0 Leucine Rich repeat LRR_7 PF13504.1 KFM12981.1 - 8.6 7.0 11.3 54 4.6 0.0 6.2 6 0 0 6 6 6 0 Leucine rich repeat UCR_hinge PF02320.11 KFM12982.1 - 6.6e-21 74.0 8.4 7e-21 73.9 5.8 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Toxin_44 PF15523.1 KFM12982.1 - 0.087 12.7 0.9 0.1 12.4 0.6 1.1 1 0 0 1 1 1 0 Putative toxin 44 GDNF PF02351.11 KFM12982.1 - 0.091 13.2 5.7 0.11 12.9 3.9 1.1 1 0 0 1 1 1 0 GDNF/GAS1 domain Nol1_Nop2_Fmu PF01189.12 KFM12983.1 - 4.6e-27 95.1 0.0 6.7e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 KFM12983.1 - 0.0034 17.3 0.0 0.0056 16.6 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Amidase PF01425.16 KFM12984.1 - 2.9e-100 336.2 0.0 3.7e-100 335.8 0.0 1.1 1 0 0 1 1 1 1 Amidase Amidase PF01425.16 KFM12985.1 - 1.1e-100 337.5 0.0 1.5e-100 337.1 0.0 1.1 1 0 0 1 1 1 1 Amidase Amidase PF01425.16 KFM12986.1 - 2.6e-101 339.6 0.0 3e-101 339.4 0.0 1.0 1 0 0 1 1 1 1 Amidase DUF4404 PF14357.1 KFM12986.1 - 0.037 14.4 0.0 0.088 13.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Peroxin-3 PF04882.7 KFM12986.1 - 0.081 11.6 0.2 0.14 10.7 0.1 1.3 1 0 0 1 1 1 0 Peroxin-3 Homeobox PF00046.24 KFM12987.1 - 1.9e-22 78.6 3.7 7.1e-22 76.7 2.5 2.1 1 0 0 1 1 1 1 Homeobox domain OAR PF03826.12 KFM12987.1 - 2.1e-06 27.0 1.5 6.2e-06 25.5 1.0 1.9 1 0 0 1 1 1 1 OAR domain LigA PF07746.6 KFM12987.1 - 0.048 13.6 0.2 0.17 11.9 0.1 2.0 1 0 0 1 1 1 0 Aromatic-ring-opening dioxygenase LigAB, LigA subunit Homeobox_KN PF05920.6 KFM12987.1 - 0.05 13.3 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 Homeobox KN domain HA PF03457.9 KFM12987.1 - 6.8 6.8 7.4 29 4.8 5.1 2.1 1 1 0 1 1 1 0 Helicase associated domain Pkinase PF00069.20 KFM12988.1 - 1.4e-66 224.3 0.0 2.1e-66 223.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM12988.1 - 7.2e-30 103.9 0.0 1.1e-29 103.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFM12988.1 - 1e-06 27.9 0.0 2e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFM12988.1 - 0.00094 18.9 0.2 0.77 9.4 0.0 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 KFM12988.1 - 0.044 12.7 0.0 0.097 11.6 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Mob1_phocein PF03637.12 KFM12989.1 - 4.1e-75 251.2 0.5 4.7e-75 251.0 0.4 1.0 1 0 0 1 1 1 1 Mob1/phocein family ATP11 PF06644.6 KFM12990.1 - 6.8e-69 232.3 1.0 8.2e-69 232.0 0.7 1.0 1 0 0 1 1 1 1 ATP11 protein EF-hand_6 PF13405.1 KFM12991.1 - 1.1e-05 24.8 1.0 0.032 14.0 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 KFM12991.1 - 4.5e-05 23.5 0.2 0.056 13.5 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KFM12991.1 - 0.0002 20.4 0.2 0.64 9.4 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 KFM12991.1 - 0.00047 19.3 0.5 1.2 8.5 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 KFM12991.1 - 0.012 15.1 0.0 2 8.1 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain pair DUF4570 PF15134.1 KFM12991.1 - 0.6 9.9 5.5 0.25 11.1 0.3 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4570) Ion_trans PF00520.26 KFM12991.1 - 0.67 9.1 3.2 4.6 6.4 2.2 2.1 1 1 0 1 1 1 0 Ion transport protein SlyX PF04102.7 KFM12991.1 - 4 7.8 10.4 23 5.4 1.0 4.5 3 2 2 5 5 5 0 SlyX FlaC_arch PF05377.6 KFM12991.1 - 7.1 6.6 19.2 0.14 12.0 0.5 5.2 5 1 1 6 6 6 0 Flagella accessory protein C (FlaC) p450 PF00067.17 KFM12992.1 - 9e-123 410.1 0.0 9.9e-123 410.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KFM12993.1 - 2.5e-121 405.4 0.0 2.9e-121 405.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EPO_TPO PF00758.13 KFM12993.1 - 0.0069 16.0 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Erythropoietin/thrombopoietin Herpes_glycop PF01528.11 KFM12994.1 - 0.02 13.6 0.0 0.022 13.5 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus glycoprotein M DUF2500 PF10694.4 KFM12994.1 - 0.036 14.0 0.3 0.055 13.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) DUF371 PF04027.8 KFM12994.1 - 0.05 13.2 0.0 0.052 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF371) Fer4_5 PF12801.2 KFM12994.1 - 0.058 13.1 2.0 0.082 12.7 1.4 1.2 1 0 0 1 1 1 0 4Fe-4S binding domain PSI_PSAK PF01241.13 KFM12994.1 - 0.068 13.1 0.0 0.092 12.7 0.0 1.2 1 0 0 1 1 1 0 Photosystem I psaG / psaK EI24 PF07264.6 KFM12994.1 - 0.07 12.5 0.0 0.073 12.4 0.0 1.1 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) OAD_gamma PF04277.8 KFM12994.1 - 0.19 12.1 1.0 0.27 11.6 0.7 1.4 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain T2SF PF00482.18 KFM12994.1 - 0.56 10.1 2.2 13 5.6 0.4 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F HLH PF00010.21 KFM12995.1 - 4.8e-08 32.5 0.9 3.6e-07 29.7 0.6 2.2 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain STIL_N PF15253.1 KFM12996.1 - 8.6e-188 624.1 0.0 1.6e-187 623.2 0.0 1.5 1 0 0 1 1 1 1 SCL-interrupting locus protein N-terminus ADK PF00406.17 KFM12997.1 - 2.6e-33 115.0 0.0 3.3e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 KFM12997.1 - 0.00066 19.9 0.1 0.0011 19.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 KFM12997.1 - 0.0023 17.3 0.0 0.014 14.8 0.0 1.9 1 1 0 2 2 2 1 Thymidylate kinase FeoC PF09012.5 KFM12997.1 - 0.047 13.3 0.0 0.097 12.3 0.0 1.5 1 0 0 1 1 1 0 FeoC like transcriptional regulator Fork_head PF00250.13 KFM12998.1 - 2.2e-54 181.4 1.1 5.1e-28 96.9 0.0 2.0 1 1 1 2 2 2 2 Fork head domain SPC12 PF06645.8 KFM12998.1 - 0.52 10.1 5.0 0.62 9.9 0.3 2.2 1 1 1 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Cornifin PF02389.10 KFM13000.1 - 0.015 15.1 5.0 0.015 15.0 3.4 1.0 1 0 0 1 1 1 0 Cornifin (SPRR) family TraB PF01963.12 KFM13001.1 - 5.7e-11 42.3 0.0 6e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 TraB family Stap_Strp_tox_C PF02876.12 KFM13001.1 - 0.052 13.7 0.0 0.074 13.2 0.0 1.3 1 0 0 1 1 1 0 Staphylococcal/Streptococcal toxin, beta-grasp domain TraB PF01963.12 KFM13002.1 - 4.7e-08 32.7 0.0 3.8e-07 29.8 0.0 1.9 1 1 0 1 1 1 1 TraB family SSF PF00474.12 KFM13004.1 - 7.7e-149 495.7 22.9 1.1e-148 495.1 15.9 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family SPATA6 PF14909.1 KFM13005.1 - 8.4e-53 178.1 0.1 1.4e-52 177.4 0.1 1.3 1 0 0 1 1 1 1 Spermatogenesis-assoc protein 6 BEN PF10523.4 KFM13006.1 - 3.7e-12 46.1 0.2 1e-11 44.7 0.1 1.8 1 1 0 1 1 1 1 BEN domain V_ATPase_I PF01496.14 KFM13006.1 - 0.48 8.2 4.5 0.72 7.6 3.1 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Yae1_N PF09811.4 KFM13007.1 - 8e-20 70.0 61.8 1.5e+04 -22.5 42.8 5.6 1 1 0 1 1 1 0 Essential protein Yae1, N terminal RRM_1 PF00076.17 KFM13009.1 - 4.6e-66 218.3 0.1 5.1e-21 74.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM13009.1 - 9.4e-39 131.2 0.0 5.5e-14 51.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM13009.1 - 3.4e-29 100.4 0.2 3.1e-10 39.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFM13009.1 - 0.00069 19.4 0.0 0.093 12.5 0.0 2.6 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 KFM13009.1 - 0.023 14.4 0.0 11 5.8 0.0 2.8 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.6 KFM13009.1 - 0.083 12.8 0.0 4.4 7.3 0.0 2.8 2 1 0 2 2 2 0 RNA binding domain RRM_2 PF04059.7 KFM13009.1 - 0.11 12.4 0.1 0.99 9.4 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif 2 Yae1_N PF09811.4 KFM13010.1 - 2.6e-10 39.6 36.8 0.083 12.4 17.6 4.5 1 1 1 2 2 2 2 Essential protein Yae1, N terminal UBX PF00789.15 KFM13011.1 - 1.1e-20 73.5 0.1 3.7e-20 71.7 0.1 2.0 2 0 0 2 2 2 1 UBX domain UBA_4 PF14555.1 KFM13011.1 - 4e-06 26.2 0.2 9.5e-06 25.0 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain ubiquitin PF00240.18 KFM13011.1 - 0.002 17.4 0.0 0.26 10.6 0.0 3.1 3 0 0 3 3 3 1 Ubiquitin family AAA_11 PF13086.1 KFM13011.1 - 0.011 15.3 0.9 0.018 14.6 0.6 1.3 1 0 0 1 1 1 0 AAA domain Ubiquitin_2 PF14560.1 KFM13011.1 - 0.014 15.6 0.0 0.48 10.7 0.0 2.9 2 0 0 2 2 2 0 Ubiquitin-like domain BPL_N PF09825.4 KFM13011.1 - 0.15 10.8 1.4 0.22 10.2 1.0 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Borrelia_P83 PF05262.6 KFM13011.1 - 0.26 9.5 6.1 0.37 9.0 4.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein AAA_23 PF13476.1 KFM13011.1 - 1.1 9.4 7.2 2.1 8.6 5.0 1.4 1 0 0 1 1 1 0 AAA domain Ank_2 PF12796.2 KFM13012.1 - 7.3e-36 122.3 4.6 1.5e-16 60.5 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFM13012.1 - 1.9e-22 78.7 7.3 1.2e-11 44.4 0.1 3.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 KFM13012.1 - 1.3e-20 72.0 3.3 1.7e-06 27.5 0.0 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 KFM13012.1 - 3.1e-19 68.9 0.9 1.3e-09 38.2 0.0 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM13012.1 - 1.1e-12 46.8 0.2 6.8e-05 22.7 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat DUF1843 PF08898.5 KFM13012.1 - 0.0064 16.5 0.1 0.072 13.1 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1843) zf-RING_2 PF13639.1 KFM13013.1 - 5e-14 51.8 5.7 6.9e-14 51.4 4.0 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFM13013.1 - 7.1e-09 35.5 6.2 1e-08 35.0 4.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM13013.1 - 1.2e-07 31.2 2.6 1.7e-07 30.7 1.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM13013.1 - 3e-06 26.7 3.5 4.7e-06 26.1 2.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFM13013.1 - 3.6e-06 26.9 5.8 9.3e-06 25.6 4.0 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KFM13013.1 - 3.7e-06 26.5 1.9 5.3e-06 26.0 1.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KFM13013.1 - 0.017 14.8 1.4 0.031 14.0 0.9 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.1 KFM13013.1 - 0.027 14.2 1.1 0.041 13.6 0.8 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 KFM13013.1 - 0.068 13.0 3.9 0.13 12.1 2.7 1.5 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 KFM13013.1 - 0.079 13.0 2.9 0.34 10.9 2.0 1.9 1 1 0 1 1 1 0 RING-variant domain BCDHK_Adom3 PF10436.4 KFM13013.1 - 0.085 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase FANCL_C PF11793.3 KFM13013.1 - 0.16 11.9 8.2 3.7 7.5 5.7 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Apc11 PF12861.2 KFM13013.1 - 0.3 10.9 6.9 3.4 7.5 5.0 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.1 KFM13013.1 - 0.39 10.4 3.6 0.43 10.3 0.4 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-Nse PF11789.3 KFM13013.1 - 0.49 9.9 2.9 0.78 9.3 2.0 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.24 KFM13013.1 - 0.6 9.8 4.1 1.4 8.6 2.8 1.7 1 1 0 1 1 1 0 PHD-finger DUF3808 PF10300.4 KFM13014.1 - 5.2e-161 536.3 3.7 5.2e-161 536.3 2.6 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_16 PF13432.1 KFM13014.1 - 2.4e-11 43.9 6.0 1.7e-05 25.3 0.0 4.2 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFM13014.1 - 1.8e-10 40.5 5.2 6.2e-09 35.6 1.3 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFM13014.1 - 1.3e-08 34.6 0.6 0.0005 20.4 0.1 4.2 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFM13014.1 - 1.1e-06 28.7 2.8 0.0062 16.9 0.8 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFM13014.1 - 1.6e-05 24.3 7.5 0.0089 15.6 1.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFM13014.1 - 2.7e-05 23.7 13.3 0.0013 18.4 1.1 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFM13014.1 - 0.00014 21.3 9.2 0.53 10.1 0.6 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFM13014.1 - 0.00018 21.0 4.6 0.002 17.7 0.3 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFM13014.1 - 0.00032 20.9 12.1 0.0015 18.7 0.9 4.3 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_4 PF07721.9 KFM13014.1 - 0.00087 19.5 0.2 0.062 13.7 0.1 3.7 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 KFM13014.1 - 0.0013 18.6 4.1 0.0063 16.4 0.6 3.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 KFM13014.1 - 0.0096 15.5 1.5 0.0096 15.5 1.0 4.8 4 1 2 6 6 6 3 TPR repeat YfdX PF10938.3 KFM13014.1 - 0.55 9.8 3.3 0.47 10.1 0.1 2.4 2 1 0 2 2 2 0 YfdX protein Apc3 PF12895.2 KFM13014.1 - 0.8 9.8 24.1 0.18 11.9 1.0 5.3 5 1 1 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 EF-hand_4 PF12763.2 KFM13015.1 - 7.8e-41 138.0 1.4 7.6e-24 83.4 0.0 3.9 4 0 0 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 KFM13015.1 - 9e-11 40.2 5.3 0.004 16.3 0.0 4.1 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 KFM13015.1 - 4.4e-09 36.3 0.2 0.34 11.0 0.0 4.5 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 KFM13015.1 - 4.9e-06 25.9 1.8 1.6 8.8 0.0 4.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 KFM13015.1 - 9.9e-06 25.0 5.8 0.023 14.3 0.3 3.4 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 KFM13015.1 - 0.00014 21.0 2.6 1.3 8.4 0.1 3.9 3 0 0 3 3 3 2 EF hand TMF_DNA_bd PF12329.3 KFM13015.1 - 0.0002 21.0 22.2 0.0002 21.0 15.4 5.0 3 1 3 6 6 4 2 TATA element modulatory factor 1 DNA binding IncA PF04156.9 KFM13015.1 - 0.00021 20.9 29.7 0.00021 20.9 20.6 3.1 2 1 1 3 3 3 2 IncA protein Reo_sigmaC PF04582.7 KFM13015.1 - 0.00087 18.5 18.0 0.0099 15.0 4.9 2.2 1 1 1 2 2 2 2 Reovirus sigma C capsid protein LXG PF04740.7 KFM13015.1 - 0.064 13.0 29.5 0.053 13.2 5.4 2.7 1 1 2 3 3 3 0 LXG domain of WXG superfamily Atg14 PF10186.4 KFM13015.1 - 0.092 11.6 31.4 0.29 10.0 8.8 2.4 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Peptidase_C98 PF15499.1 KFM13015.1 - 0.12 11.5 6.1 0.2 10.9 4.2 1.3 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Prominin PF05478.6 KFM13015.1 - 0.58 7.6 17.7 0.79 7.1 12.3 1.1 1 0 0 1 1 1 0 Prominin Laminin_II PF06009.7 KFM13015.1 - 3.7 7.3 23.5 7.6 6.2 2.3 2.8 1 1 1 2 2 2 0 Laminin Domain II Spc7 PF08317.6 KFM13015.1 - 4.8 5.7 47.6 0.26 9.8 14.8 2.7 2 1 1 3 3 3 0 Spc7 kinetochore protein ADIP PF11559.3 KFM13015.1 - 7.7 6.4 43.6 0.1 12.4 5.1 3.2 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding COG2 PF06148.6 KFM13015.1 - 8.5 6.2 24.1 2.4 8.0 7.3 3.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Tweety PF04906.8 KFM13015.1 - 8.7 4.6 13.7 3.8 5.8 0.4 2.3 1 1 0 2 2 2 0 Tweety Peptidase_M16 PF00675.15 KFM13016.1 - 4.9e-41 139.9 2.0 3.6e-40 137.1 0.0 3.1 3 1 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KFM13016.1 - 1.2e-33 116.3 2.3 3.5e-19 69.1 0.0 2.8 3 0 0 3 3 3 2 Peptidase M16 inactive domain IBN_N PF03810.14 KFM13016.1 - 0.077 12.9 0.2 0.21 11.5 0.1 1.7 1 0 0 1 1 1 0 Importin-beta N-terminal domain Nop14 PF04147.7 KFM13016.1 - 5.8 4.7 25.3 9.3 4.0 17.6 1.2 1 0 0 1 1 1 0 Nop14-like family Ras PF00071.17 KFM13017.1 - 3.9e-61 205.1 0.5 4.6e-61 204.9 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM13017.1 - 6.9e-19 68.4 0.0 9.9e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM13017.1 - 4.3e-13 48.8 0.2 5.2e-13 48.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFM13017.1 - 1.6e-05 24.1 0.0 2.4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KFM13017.1 - 3.2e-05 23.2 0.0 0.00013 21.2 0.0 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 KFM13017.1 - 0.00014 21.3 0.1 0.00035 20.0 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KFM13017.1 - 0.0076 15.5 0.0 3.5 6.8 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B MMR_HSR1 PF01926.18 KFM13017.1 - 0.012 15.6 0.0 0.022 14.7 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.15 KFM13017.1 - 0.012 14.2 0.1 2.3 6.8 0.0 3.0 2 1 1 3 3 3 0 G-protein alpha subunit DUF258 PF03193.11 KFM13017.1 - 0.047 12.8 0.0 8.1 5.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 KFM13017.1 - 0.13 12.1 0.1 0.34 10.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain Thioredoxin_7 PF13899.1 KFM13019.1 - 1e-17 63.9 0.0 1.6e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.15 KFM13019.1 - 8.7e-08 31.7 0.0 1.3e-07 31.2 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KFM13019.1 - 1.4e-05 25.2 0.1 9.3e-05 22.5 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredox_DsbH PF03190.10 KFM13019.1 - 0.00054 19.7 0.1 0.00069 19.3 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_8 PF13905.1 KFM13019.1 - 0.00068 19.7 0.0 0.0023 17.9 0.0 1.8 1 1 0 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.1 KFM13019.1 - 0.00078 19.0 0.0 0.0013 18.3 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 KFM13019.1 - 0.01 15.5 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family Glutaredoxin PF00462.19 KFM13019.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.6 2 0 0 2 2 2 0 Glutaredoxin NAC PF01849.13 KFM13020.1 - 1e-22 79.3 0.1 1.8e-22 78.6 0.1 1.4 1 0 0 1 1 1 1 NAC domain DUF3480 PF11979.3 KFM13021.1 - 3.7e-185 614.5 0.0 5.2e-185 614.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3480) SARA PF11409.3 KFM13021.1 - 3e-22 78.2 11.8 8.8e-22 76.7 8.2 1.9 1 0 0 1 1 1 1 Smad anchor for receptor activation (SARA) FYVE PF01363.16 KFM13021.1 - 1.4e-19 69.7 16.0 1.4e-19 69.7 11.1 2.3 2 0 0 2 2 2 1 FYVE zinc finger C2 PF00168.25 KFM13022.1 - 5.9e-05 22.8 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 C2 domain PRP38 PF03371.10 KFM13023.1 - 6.1e-68 227.8 1.2 7.6e-68 227.4 0.9 1.1 1 0 0 1 1 1 1 PRP38 family PRP38_assoc PF12871.2 KFM13023.1 - 0.00014 22.3 49.7 0.00014 22.3 34.4 2.2 1 1 1 2 2 2 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term PAP_assoc PF03828.14 KFM13024.1 - 4.1e-31 106.7 0.8 4.5e-16 58.5 0.1 3.0 2 0 0 2 2 2 2 Cid1 family poly A polymerase zf-CCHC PF00098.18 KFM13024.1 - 1.8e-12 46.5 22.1 3.3e-05 23.5 0.8 4.0 3 0 0 3 3 3 3 Zinc knuckle NTP_transf_2 PF01909.18 KFM13024.1 - 2e-10 40.8 0.0 1.2e-06 28.6 0.0 2.8 2 0 0 2 2 2 2 Nucleotidyltransferase domain zf-CCHC_4 PF14392.1 KFM13024.1 - 1.5e-05 24.5 18.1 0.058 13.0 0.6 3.7 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_2 PF13696.1 KFM13024.1 - 1.6e-05 24.2 21.4 0.0066 15.9 0.7 4.7 4 0 0 4 4 4 3 Zinc knuckle Ubiq_cyt_C_chap PF03981.7 KFM13024.1 - 0.05 13.4 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone GSHPx PF00255.14 KFM13025.1 - 3.5e-36 122.8 0.0 4.8e-36 122.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 KFM13025.1 - 0.00016 21.3 0.0 0.00096 18.8 0.0 2.1 1 1 0 1 1 1 1 AhpC/TSA family SCO1-SenC PF02630.9 KFM13025.1 - 0.00025 20.7 0.0 0.053 13.1 0.0 2.4 2 0 0 2 2 2 2 SCO1/SenC Shisa PF13908.1 KFM13026.1 - 9.4e-05 22.6 5.7 9.4e-05 22.6 4.0 2.0 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator Adeno_E3_CR2 PF02439.10 KFM13026.1 - 0.046 13.2 1.4 0.081 12.4 1.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Metallothio_Cad PF07846.6 KFM13026.1 - 0.099 12.5 2.7 0.22 11.4 1.9 1.6 1 0 0 1 1 1 0 Metallothionein family PDR_assoc PF08370.6 KFM13026.1 - 0.11 12.0 5.0 0.17 11.4 3.5 1.4 1 1 0 1 1 1 0 Plant PDR ABC transporter associated DUF2668 PF10873.3 KFM13026.1 - 2 8.5 6.4 2.9 8.0 4.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2668) Sel1 PF08238.7 KFM13027.1 - 1.3e-16 60.6 0.9 0.00016 22.1 0.0 4.6 5 0 0 5 5 5 4 Sel1 repeat DUF4315 PF14193.1 KFM13027.1 - 0.02 14.8 1.1 0.034 14.0 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) LRR_4 PF12799.2 KFM13028.1 - 0.0034 16.9 9.4 0.0034 16.9 0.1 4.0 1 1 3 4 4 4 2 Leucine Rich repeats (2 copies) His_kinase PF06580.8 KFM13028.1 - 0.0088 15.9 0.6 0.032 14.1 0.4 1.9 1 0 0 1 1 1 1 Histidine kinase LRR_6 PF13516.1 KFM13028.1 - 0.016 15.2 5.8 0.7 10.1 0.1 4.1 4 0 0 4 4 4 0 Leucine Rich repeat DNA_alkylation PF08713.6 KFM13028.1 - 0.017 14.6 1.7 4.9 6.6 0.1 2.7 3 0 0 3 3 3 0 DNA alkylation repair enzyme LRR_8 PF13855.1 KFM13028.1 - 0.032 13.9 8.0 0.052 13.3 1.4 3.8 2 1 1 3 3 3 0 Leucine rich repeat RIX1 PF08167.7 KFM13028.1 - 0.06 13.0 9.1 0.28 10.8 0.1 3.7 2 1 1 3 3 3 0 rRNA processing/ribosome biogenesis LRR_1 PF00560.28 KFM13028.1 - 0.35 11.0 3.6 13 6.3 0.0 4.5 3 1 1 4 4 4 0 Leucine Rich Repeat ECH PF00378.15 KFM13029.1 - 9.2e-53 178.8 0.7 1e-52 178.7 0.5 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 KFM13029.1 - 0.024 14.4 0.1 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 SCP2 PF02036.12 KFM13030.1 - 2.3e-29 101.6 0.9 4.8e-29 100.6 0.6 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family Thiolase_C PF02803.13 KFM13030.1 - 1.5e-12 47.0 0.3 2.8e-11 42.9 0.1 2.9 2 1 0 2 2 2 1 Thiolase, C-terminal domain Thiolase_N PF00108.18 KFM13030.1 - 1.4e-09 37.3 0.0 4.2e-09 35.7 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Alkyl_sulf_C PF14864.1 KFM13030.1 - 5.9e-07 29.5 0.0 1.1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal ketoacyl-synt PF00109.21 KFM13030.1 - 0.00089 18.8 2.5 0.0031 17.0 1.0 2.3 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KFM13030.1 - 0.00096 18.9 0.2 0.12 12.1 0.0 3.2 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain ACP_syn_III PF08545.5 KFM13030.1 - 0.0024 17.4 2.7 0.0081 15.7 0.1 2.7 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.6 KFM13030.1 - 0.019 13.4 0.2 0.24 9.8 0.0 2.2 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) DSBA PF01323.15 KFM13030.1 - 0.074 12.6 0.0 0.44 10.0 0.0 2.3 3 0 0 3 3 3 0 DSBA-like thioredoxin domain LRR_8 PF13855.1 KFM13031.1 - 3.9e-76 250.7 56.2 1.1e-15 57.1 2.4 8.5 5 1 1 8 8 8 8 Leucine rich repeat LRR_4 PF12799.2 KFM13031.1 - 1.3e-51 171.4 70.3 4.6e-07 29.3 3.0 12.2 3 2 12 15 15 15 15 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM13031.1 - 6.9e-44 141.1 48.6 0.0026 17.5 0.3 18.3 18 2 1 19 19 19 13 Leucine Rich Repeat LRR_5 PF13306.1 KFM13031.1 - 5.3e-23 81.1 6.3 7e-07 29.0 0.1 5.1 2 1 4 6 6 6 6 Leucine rich repeats (6 copies) LRR_7 PF13504.1 KFM13031.1 - 3.1e-22 74.7 50.3 0.13 12.5 0.1 16.2 17 0 0 17 17 17 9 Leucine rich repeat LRR_6 PF13516.1 KFM13031.1 - 5.6e-19 66.0 59.3 0.069 13.2 0.1 15.4 17 1 1 18 18 18 9 Leucine Rich repeat LRR_9 PF14580.1 KFM13031.1 - 2.5e-10 40.2 17.6 0.046 13.2 0.2 6.6 1 1 6 7 7 7 6 Leucine-rich repeat FNIP PF05725.7 KFM13031.1 - 0.00079 19.3 17.2 5 7.1 0.2 7.7 4 2 2 6 6 6 2 FNIP Repeat LRRNT PF01462.13 KFM13031.1 - 1.4 8.4 4.6 43 3.7 0.0 4.1 5 0 0 5 5 5 0 Leucine rich repeat N-terminal domain SDF PF00375.13 KFM13032.1 - 2.8e-128 427.9 28.2 3.2e-128 427.7 19.5 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family FeoB_C PF07664.7 KFM13032.1 - 0.62 9.5 7.4 3.5 7.1 0.5 4.5 4 0 0 4 4 4 0 Ferrous iron transport protein B C terminus Carn_acyltransf PF00755.15 KFM13033.1 - 2.8e-186 620.1 0.0 3.2e-186 619.9 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF866 PF05907.8 KFM13034.1 - 1.7e-67 225.8 0.2 1.9e-67 225.7 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Mago_nashi PF02792.9 KFM13035.1 - 5.4e-63 210.9 0.1 6e-63 210.8 0.0 1.0 1 0 0 1 1 1 1 Mago nashi protein Ldl_recept_a PF00057.13 KFM13036.1 - 2.5e-78 257.6 137.8 2.6e-14 52.8 6.8 7.9 8 0 0 8 8 7 7 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.12 KFM13036.1 - 7.3e-64 211.8 9.3 2e-15 56.8 0.0 5.4 5 0 0 5 5 5 5 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.1 KFM13036.1 - 3.1e-16 59.1 58.6 2.2e-09 37.2 5.6 5.9 5 0 0 5 5 3 3 Coagulation Factor Xa inhibitory site cEGF PF12662.2 KFM13036.1 - 7.9e-08 31.8 14.3 6.4e-05 22.4 0.5 5.5 3 0 0 3 3 3 2 Complement Clr-like EGF-like SGL PF08450.7 KFM13036.1 - 1.2e-06 28.0 0.8 0.014 14.7 0.0 2.6 1 1 0 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region EGF_CA PF07645.10 KFM13036.1 - 3e-06 27.1 11.3 3e-06 27.1 7.8 10.5 6 2 2 8 8 4 2 Calcium-binding EGF domain EGF PF00008.22 KFM13036.1 - 5.1e-05 23.1 20.3 6.3e-05 22.8 3.5 9.4 9 0 0 9 9 9 3 EGF-like domain SKG6 PF08693.5 KFM13036.1 - 0.00016 20.9 0.4 0.00036 19.7 0.3 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain NHL PF01436.16 KFM13036.1 - 0.00099 18.9 1.6 2.2 8.4 0.0 5.6 7 0 0 7 7 7 1 NHL repeat Arylesterase PF01731.15 KFM13036.1 - 0.02 14.8 0.0 3.6 7.6 0.0 3.4 3 0 0 3 3 3 0 Arylesterase TMEM154 PF15102.1 KFM13036.1 - 0.2 11.3 7.4 2.5 7.8 5.2 2.1 1 1 0 1 1 1 0 TMEM154 protein family zf-H2C2_2 PF13465.1 KFM13037.1 - 7.2e-15 54.4 20.2 5.8e-06 26.3 0.5 5.9 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 KFM13037.1 - 4.3e-14 51.9 31.9 0.0018 18.5 0.6 6.8 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM13037.1 - 3e-10 39.6 27.7 0.0028 17.8 0.1 6.4 6 0 0 6 6 6 4 C2H2-type zinc finger zf-met PF12874.2 KFM13037.1 - 0.22 11.7 6.2 1.6 9.0 0.1 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-LYAR PF08790.6 KFM13037.1 - 0.61 9.8 4.0 10 5.9 0.0 4.3 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger zf-C2H2_jaz PF12171.3 KFM13037.1 - 0.66 10.1 7.3 26 5.0 0.0 3.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Ndc1_Nup PF09531.5 KFM13038.1 - 2.1e-169 564.8 10.5 2.4e-169 564.6 7.3 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Yip1 PF04893.12 KFM13039.1 - 3.3e-20 72.2 13.5 4.6e-20 71.8 9.3 1.3 1 0 0 1 1 1 1 Yip1 domain ELF PF03317.8 KFM13039.1 - 0.12 11.6 1.5 0.18 11.1 1.1 1.2 1 0 0 1 1 1 0 ELF protein T4_deiodinase PF00837.12 KFM13040.1 - 5.9e-24 84.3 0.0 6.5e-24 84.2 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase LRR_4 PF12799.2 KFM13042.1 - 1.4e-05 24.5 7.4 0.0048 16.4 0.4 3.4 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KFM13042.1 - 3.4e-05 23.4 6.3 0.47 10.6 0.1 4.7 4 0 0 4 4 4 2 Leucine Rich repeat LRR_8 PF13855.1 KFM13042.1 - 0.0016 18.1 8.3 0.013 15.2 0.2 3.4 2 1 1 3 3 3 1 Leucine rich repeat LRR_1 PF00560.28 KFM13042.1 - 0.027 14.4 7.6 2 8.7 0.2 4.3 2 2 1 3 3 3 0 Leucine Rich Repeat LRR_7 PF13504.1 KFM13042.1 - 0.56 10.6 10.2 8.4 7.0 0.3 4.8 5 0 0 5 5 5 0 Leucine rich repeat Ldl_recept_a PF00057.13 KFM13043.1 - 1.3e-11 44.2 29.3 2.5e-05 24.0 5.0 3.3 3 0 0 3 3 3 3 Low-density lipoprotein receptor domain class A BSMAP PF12280.3 KFM13044.1 - 1.1e-74 250.8 0.4 1.1e-74 250.8 0.3 2.2 1 1 1 2 2 2 2 Brain specific membrane anchored protein Med26 PF08711.6 KFM13045.1 - 1.2e-15 56.7 0.4 1.2e-15 56.7 0.3 2.0 2 0 0 2 2 2 1 TFIIS helical bundle-like domain TFIIS_M PF07500.9 KFM13045.1 - 2.5e-07 30.7 0.3 4.3e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain Lipase_GDSL_3 PF14606.1 KFM13045.1 - 0.1 12.3 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family CUB PF00431.15 KFM13047.1 - 1.4e-90 298.7 0.0 1.6e-31 108.6 0.0 3.0 3 0 0 3 3 3 3 CUB domain CUB_2 PF02408.15 KFM13047.1 - 0.022 14.3 0.2 1.1 8.7 0.0 3.0 4 0 0 4 4 4 0 CUB-like domain NAD_binding_1 PF00175.16 KFM13048.1 - 3.6e-13 50.0 0.0 1.7e-12 47.8 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KFM13048.1 - 2.4e-11 43.5 0.0 4e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Oxidored-like PF09791.4 KFM13048.1 - 7.8e-11 41.2 2.1 5e-10 38.6 1.8 2.0 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal NAD_binding_6 PF08030.7 KFM13048.1 - 0.00019 21.3 0.1 0.0044 16.9 0.0 2.5 2 1 0 3 3 3 1 Ferric reductase NAD binding domain TrbC_Ftype PF09673.5 KFM13048.1 - 0.0061 16.1 0.0 0.94 9.1 0.0 2.3 2 0 0 2 2 2 2 Type-F conjugative transfer system pilin assembly protein PEP-utilizers_C PF02896.13 KFM13048.1 - 0.18 10.6 0.0 0.24 10.2 0.0 1.1 1 0 0 1 1 1 0 PEP-utilising enzyme, TIM barrel domain PDCD9 PF07147.7 KFM13049.1 - 2.3e-25 89.3 0.0 4.6e-25 88.2 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial 28S ribosomal protein S30 (PDCD9) Thi4 PF01946.12 KFM13049.1 - 0.064 12.3 0.0 0.14 11.1 0.0 1.5 2 0 0 2 2 2 0 Thi4 family SSDP PF04503.8 KFM13050.1 - 1.6e-107 359.5 67.5 3.7e-84 282.9 35.8 2.0 1 1 1 2 2 2 2 Single-stranded DNA binding protein, SSDP PAT1 PF09770.4 KFM13050.1 - 7.3 4.6 12.5 7 4.7 8.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 4HBT PF03061.17 KFM13051.1 - 6.1e-23 80.7 0.4 1.2e-10 41.3 0.0 2.6 3 0 0 3 3 3 2 Thioesterase superfamily tRNA-synt_2b PF00587.20 KFM13052.1 - 4.4e-34 117.5 0.0 6.1e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KFM13052.1 - 3.1e-06 27.0 0.0 5.3e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 KFM13052.1 - 0.16 10.7 0.0 0.27 9.9 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) FAD_binding_4 PF01565.18 KFM13053.1 - 1.6e-17 63.2 0.1 2.6e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain TMEM61 PF15105.1 KFM13054.1 - 6.1e-45 153.1 0.9 6.9e-45 153.0 0.6 1.0 1 0 0 1 1 1 1 TMEM61 protein family Peptidase_S8 PF00082.17 KFM13055.1 - 3.5e-32 111.7 0.7 4.7e-32 111.2 0.5 1.2 1 0 0 1 1 1 1 Subtilase family Tox-GHH PF15636.1 KFM13055.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin PAP2 PF01569.16 KFM13059.1 - 1.3e-20 73.4 1.2 1.3e-20 73.4 0.8 1.7 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 KFM13059.1 - 3.7e-06 27.1 1.5 3.7e-06 27.1 1.0 1.8 2 0 0 2 2 2 1 PAP2 superfamily C-terminal YhhN PF07947.9 KFM13059.1 - 0.0082 15.5 0.7 0.016 14.5 0.5 1.5 1 0 0 1 1 1 1 YhhN-like protein Antimicrobial13 PF08108.6 KFM13059.1 - 0.2 11.5 1.1 0.79 9.6 0.0 2.3 2 0 0 2 2 2 0 Halocidin family Pkinase PF00069.20 KFM13060.1 - 3.7e-68 229.5 0.0 4.8e-68 229.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM13060.1 - 1.2e-36 126.0 0.0 2.2e-36 125.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM13060.1 - 4.6e-06 25.8 0.0 6.7e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KFM13060.1 - 0.00014 21.3 0.3 0.0005 19.4 0.2 1.8 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 KFM13060.1 - 0.002 17.2 0.2 0.0044 16.1 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFM13060.1 - 0.025 14.3 0.0 0.049 13.3 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family YukC PF10140.4 KFM13060.1 - 0.14 10.6 0.0 0.21 10.1 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC hSH3 PF14603.1 KFM13061.1 - 2.5e-13 49.8 0.0 4.4e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Helically-extended SH3 domain ARD PF03079.9 KFM13061.1 - 0.011 15.6 0.6 0.014 15.3 0.4 1.2 1 0 0 1 1 1 0 ARD/ARD' family MACPF PF01823.14 KFM13062.1 - 5.2e-43 147.1 2.7 4e-42 144.3 0.2 2.6 2 1 1 3 3 3 1 MAC/Perforin domain Ldl_recept_a PF00057.13 KFM13062.1 - 2.7e-08 33.5 10.5 1.1e-07 31.5 7.2 2.2 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A TSP_1 PF00090.14 KFM13062.1 - 1.6e-06 28.1 35.0 1.9e-05 24.6 7.0 3.5 3 0 0 3 3 3 2 Thrombospondin type 1 domain DUF3887 PF13026.1 KFM13062.1 - 0.11 12.7 0.2 4.7 7.5 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3887) hEGF PF12661.2 KFM13062.1 - 0.92 9.7 9.1 0.11 12.6 1.1 3.0 2 0 0 2 2 2 0 Human growth factor-like EGF PID PF00640.18 KFM13063.1 - 5.7e-24 84.6 0.1 9.3e-24 84.0 0.1 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Peptidase_M48 PF01435.13 KFM13064.1 - 2.2e-31 109.1 0.2 3.1e-31 108.6 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M48 DUF2201_N PF13203.1 KFM13064.1 - 0.011 14.9 0.3 0.017 14.3 0.2 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Peptidase_U49 PF10463.4 KFM13064.1 - 2.4 7.8 6.2 2.2 8.0 0.9 2.7 3 1 1 4 4 4 0 Peptidase U49 SWIRM PF04433.12 KFM13065.1 - 4.7e-20 71.5 0.3 1.3e-19 70.0 0.0 2.0 2 0 0 2 2 2 1 SWIRM domain JAB PF01398.16 KFM13065.1 - 2.3e-13 49.8 0.0 5.7e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Myb_DNA-binding PF00249.26 KFM13065.1 - 2.3e-11 43.5 0.1 6.2e-11 42.1 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Prok-JAB PF14464.1 KFM13065.1 - 1.6e-09 37.2 0.0 4.3e-09 35.8 0.0 1.7 1 1 0 1 1 1 1 Prokaryotic homologs of the JAB domain Myb_DNA-bind_6 PF13921.1 KFM13065.1 - 7.9e-06 25.8 0.8 2.6e-05 24.2 0.5 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain UPF0172 PF03665.8 KFM13065.1 - 0.0075 15.7 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) Ank_2 PF12796.2 KFM13066.1 - 2.4e-114 373.9 38.7 6.2e-24 84.1 0.4 7.0 3 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 KFM13066.1 - 3.3e-105 339.0 27.1 1.9e-09 36.8 0.1 15.0 15 0 0 15 15 15 14 Ankyrin repeat Ank_4 PF13637.1 KFM13066.1 - 1.9e-79 260.7 28.8 3.2e-11 43.4 0.0 11.8 4 3 9 13 13 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM13066.1 - 6.1e-77 245.8 21.8 1.2e-05 25.1 0.0 15.0 15 0 0 15 15 15 13 Ankyrin repeat Ank_5 PF13857.1 KFM13066.1 - 1.7e-72 237.7 19.0 5.8e-11 42.2 0.1 12.6 2 2 11 13 13 13 12 Ankyrin repeats (many copies) DUF3447 PF11929.3 KFM13066.1 - 0.0026 17.5 0.0 4.5 7.1 0.0 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF3447) DUF2462 PF09495.5 KFM13066.1 - 0.074 13.8 0.8 0.72 10.6 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2462) Shigella_OspC PF06128.6 KFM13066.1 - 1.6 8.1 5.7 72 2.7 0.0 4.4 5 1 1 6 6 6 0 Shigella flexneri OspC protein FGGY_C PF02782.11 KFM13067.1 - 9.8e-47 159.1 0.1 1.5e-46 158.5 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KFM13067.1 - 3.9e-29 101.6 0.0 5.6e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 KFM13067.1 - 0.022 14.0 0.1 0.12 11.6 0.0 2.2 3 0 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family zf-RING_2 PF13639.1 KFM13068.1 - 3.8e-10 39.4 8.8 5.8e-10 38.8 6.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KFM13068.1 - 6.6e-10 38.4 7.7 1.2e-09 37.6 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFM13068.1 - 1.6e-09 37.5 8.6 3.2e-09 36.5 6.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 KFM13068.1 - 3.3e-09 36.6 8.8 5.7e-09 35.8 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM13068.1 - 4.7e-09 35.7 4.2 7.1e-09 35.2 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFM13068.1 - 5.3e-06 26.0 2.1 5.3e-06 26.0 1.5 1.8 2 1 0 2 2 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 KFM13068.1 - 1.1e-05 25.0 8.8 0.00017 21.2 6.6 2.3 1 1 1 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 KFM13068.1 - 0.0017 18.1 4.4 0.042 13.6 2.4 2.1 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-MIZ PF02891.15 KFM13068.1 - 0.0064 15.9 7.5 0.011 15.2 5.2 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 KFM13068.1 - 0.01 15.3 4.2 0.017 14.6 2.9 1.4 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-Sec23_Sec24 PF04810.10 KFM13068.1 - 0.011 15.2 4.1 1 8.9 0.0 2.5 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger Baculo_IE-1 PF05290.6 KFM13068.1 - 0.019 14.6 3.8 0.027 14.2 2.6 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-rbx1 PF12678.2 KFM13068.1 - 0.033 14.2 6.1 0.14 12.2 4.2 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger DUF4020 PF13212.1 KFM13068.1 - 0.054 13.0 0.0 0.064 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4020) zf-B_box PF00643.19 KFM13068.1 - 0.072 12.9 4.0 1.1 9.2 0.2 3.0 3 0 0 3 3 3 0 B-box zinc finger TerY-C PF15616.1 KFM13068.1 - 0.14 12.1 5.3 0.24 11.3 3.7 1.5 1 1 0 1 1 1 0 TerY-C metal binding domain Elf1 PF05129.8 KFM13068.1 - 0.22 11.2 6.5 4.8 6.9 4.0 2.4 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-RING_4 PF14570.1 KFM13068.1 - 0.28 10.7 7.1 8.6 6.0 5.7 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain HypA PF01155.14 KFM13068.1 - 0.48 10.1 2.7 0.7 9.6 1.9 1.4 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-AN1 PF01428.11 KFM13068.1 - 0.48 10.3 5.0 1.3 8.9 0.8 2.4 2 0 0 2 2 2 0 AN1-like Zinc finger Fer2 PF00111.22 KFM13068.1 - 0.66 9.7 4.6 3.8 7.3 3.2 2.0 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain zf-RING_3 PF14369.1 KFM13068.1 - 0.67 9.9 6.6 7.5 6.6 0.1 2.5 2 1 0 2 2 2 0 zinc-finger zf-FCS PF06467.9 KFM13068.1 - 1.3 8.6 7.2 15 5.3 2.0 3.1 3 1 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif zf-Di19 PF05605.7 KFM13068.1 - 1.3 9.1 7.2 36 4.5 4.9 2.3 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DZR PF12773.2 KFM13068.1 - 1.5 8.7 7.7 13 5.7 0.1 2.5 1 1 1 2 2 2 0 Double zinc ribbon Cys_rich_CPXG PF14255.1 KFM13068.1 - 1.7 8.5 4.3 12 5.7 0.2 2.3 2 0 0 2 2 2 0 Cysteine-rich CPXCG Zn_Tnp_IS1 PF03811.8 KFM13068.1 - 2.6 7.6 5.5 23 4.6 0.1 2.7 2 1 0 2 2 2 0 InsA N-terminal domain zf-H2C2_2 PF13465.1 KFM13068.1 - 3.6 8.0 6.3 50 4.4 0.1 2.9 2 1 0 2 2 2 0 Zinc-finger double domain RPA_interact_C PF14768.1 KFM13068.1 - 3.7 8.0 7.9 15 6.0 1.1 2.1 2 0 0 2 2 2 0 Replication protein A interacting C-terminal FYVE PF01363.16 KFM13068.1 - 4.1 7.3 9.1 35 4.3 6.3 2.5 1 1 0 1 1 1 0 FYVE zinc finger Lar_restr_allev PF14354.1 KFM13068.1 - 8.4 6.7 7.3 1.1e+02 3.1 5.0 2.3 1 1 0 1 1 1 0 Restriction alleviation protein Lar HOOK PF05622.7 KFM13069.1 - 0 1103.0 76.1 0 1102.9 52.8 1.0 1 0 0 1 1 1 1 HOOK protein ATG16 PF08614.6 KFM13069.1 - 1.9e-08 34.3 86.6 0.00019 21.3 13.4 6.1 1 1 4 5 5 5 4 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 KFM13069.1 - 7.4e-05 22.0 16.9 0.0024 17.1 0.3 3.4 3 0 0 3 3 3 3 Reovirus sigma C capsid protein Spc7 PF08317.6 KFM13069.1 - 0.0011 17.6 13.1 0.0011 17.6 9.1 4.8 1 1 3 5 5 5 1 Spc7 kinetochore protein DUF869 PF05911.6 KFM13069.1 - 2 6.5 79.5 0.044 12.0 18.1 3.0 1 1 2 3 3 3 0 Plant protein of unknown function (DUF869) Vip3A_N PF12495.3 KFM13069.1 - 3 7.5 16.2 0.58 9.8 1.1 3.6 2 2 2 4 4 4 0 Vegetative insecticide protein 3A N terminal PspA_IM30 PF04012.7 KFM13069.1 - 6.6 6.0 72.5 2.3 7.5 3.3 5.2 2 2 3 5 5 5 0 PspA/IM30 family p450 PF00067.17 KFM13070.1 - 2.9e-132 441.4 0.3 3.4e-132 441.2 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KFM13071.1 - 3.3e-33 114.8 0.1 3.7e-33 114.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KFM13072.1 - 2.1e-10 39.7 0.5 2.1e-10 39.7 0.4 1.0 1 0 0 1 1 1 1 Cytochrome P450 PhnA PF03831.9 KFM13073.1 - 0.11 11.8 0.1 0.2 11.0 0.0 1.5 1 1 0 1 1 1 0 PhnA protein CTF_NFI PF00859.13 KFM13075.1 - 2.5e-134 447.6 42.0 6.5e-134 446.3 29.1 1.6 1 1 0 1 1 1 1 CTF/NF-I family transcription modulation region TM2 PF05154.11 KFM13076.1 - 9.1e-18 64.2 5.6 1.3e-17 63.6 3.9 1.2 1 0 0 1 1 1 1 TM2 domain PDZ PF00595.19 KFM13077.1 - 1.3e-146 477.0 44.4 3.1e-18 65.7 0.0 11.0 11 0 0 11 11 11 10 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM13077.1 - 2.9e-49 164.8 20.6 1.9e-05 24.4 0.0 10.7 10 0 0 10 10 10 10 PDZ domain L27_2 PF09045.5 KFM13077.1 - 1.9e-23 81.7 9.7 5e-23 80.4 6.7 1.8 1 0 0 1 1 1 1 L27_2 Tricorn_PDZ PF14685.1 KFM13077.1 - 1.2e-06 28.1 13.7 1.3 8.9 0.1 8.4 8 0 0 8 8 8 3 Tricorn protease PDZ domain Ank_2 PF12796.2 KFM13078.1 - 9.3e-25 86.7 5.4 5.3e-17 61.9 0.2 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFM13078.1 - 4.4e-22 77.5 5.2 2.5e-13 49.8 0.1 3.5 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 KFM13078.1 - 7e-22 76.0 2.1 5e-06 26.0 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 KFM13078.1 - 2.3e-20 72.5 4.8 1e-08 35.4 0.0 4.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM13078.1 - 5e-17 60.3 1.4 0.00045 20.1 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat UCH PF00443.24 KFM13080.1 - 7.5e-41 140.0 16.6 3.4e-32 111.6 10.6 3.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFM13080.1 - 4.7e-20 72.2 1.1 2.9e-17 63.0 0.7 3.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Ded_cyto PF06920.8 KFM13081.1 - 2.9e-78 261.2 2.7 3.2e-78 261.0 0.8 2.0 2 0 0 2 2 2 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 KFM13081.1 - 1.1e-55 188.1 0.1 4.2e-55 186.2 0.1 2.0 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.3 KFM13081.1 - 1.1e-34 118.1 0.0 6.4e-33 112.4 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3398) Fibrinogen_C PF00147.13 KFM13082.1 - 3.2e-54 184.0 0.3 5.2e-54 183.3 0.2 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Reo_sigmaC PF04582.7 KFM13082.1 - 0.011 14.8 0.2 0.016 14.4 0.1 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein EF1_GNE PF00736.14 KFM13082.1 - 0.17 11.5 3.4 2.3 7.9 0.1 2.7 2 0 0 2 2 2 0 EF-1 guanine nucleotide exchange domain RTBV_P46 PF06216.6 KFM13082.1 - 0.23 10.2 10.1 0.055 12.3 1.4 2.1 1 1 1 2 2 2 0 Rice tungro bacilliform virus P46 protein Peptidase_S64 PF08192.6 KFM13082.1 - 0.41 8.9 7.0 0.58 8.4 4.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 IncA PF04156.9 KFM13082.1 - 0.9 9.1 20.4 0.015 14.8 7.7 2.1 1 1 1 2 2 2 0 IncA protein Cortex-I_coil PF09304.5 KFM13082.1 - 4.1 7.5 18.4 1.1 9.2 4.6 2.3 1 1 1 2 2 2 0 Cortexillin I, coiled coil DUF972 PF06156.8 KFM13082.1 - 8.4 6.8 13.8 0.78 10.1 4.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF1664 PF07889.7 KFM13082.1 - 8.9 6.1 11.6 0.63 9.8 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Peptidase_C54 PF03416.14 KFM13083.1 - 3e-113 377.6 0.0 4.1e-113 377.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 Alg6_Alg8 PF03155.10 KFM13084.1 - 3.6e-157 523.9 29.8 4.3e-157 523.7 20.7 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family CENP-R PF06729.7 KFM13085.1 - 1.2e-61 206.4 5.1 1.4e-61 206.1 3.6 1.0 1 0 0 1 1 1 1 Kinetochore component, CENP-R EF-hand_7 PF13499.1 KFM13086.1 - 4.8e-15 55.4 1.9 7.7e-07 29.1 0.4 3.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 KFM13086.1 - 1.6e-12 45.7 2.8 0.0022 17.1 0.0 4.5 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 KFM13086.1 - 9.6e-10 37.9 5.5 2.2e-06 27.1 0.0 3.8 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 KFM13086.1 - 3e-08 32.8 2.5 0.0017 18.0 0.0 4.2 4 1 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.1 KFM13086.1 - 6.4e-07 28.4 2.1 0.11 11.8 0.2 3.6 3 0 0 3 3 3 3 EF hand EFhand_Ca_insen PF08726.5 KFM13086.1 - 0.017 15.0 0.0 0.04 13.8 0.0 1.6 1 0 0 1 1 1 0 Ca2+ insensitive EF hand EF_assoc_2 PF08356.7 KFM13086.1 - 0.021 14.5 0.0 0.056 13.2 0.0 1.7 1 0 0 1 1 1 0 EF hand associated Prot_inhib_II PF02428.10 KFM13086.1 - 2.8 8.0 6.2 0.36 10.9 0.2 2.6 2 0 0 2 2 2 0 Potato type II proteinase inhibitor family PGM_PMM_I PF02878.11 KFM13087.1 - 9.7e-34 115.8 0.1 1.6e-33 115.1 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 KFM13087.1 - 9.2e-31 106.2 0.0 1.6e-30 105.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 KFM13087.1 - 8.2e-18 64.6 0.0 1.8e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KFM13087.1 - 1e-09 38.2 0.0 2.2e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Pkinase_Tyr PF07714.12 KFM13088.1 - 4e-92 307.9 0.0 5.1e-92 307.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM13088.1 - 1.7e-44 151.9 0.0 2.3e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Fz PF01392.17 KFM13088.1 - 4.2e-24 85.1 4.9 4.2e-24 85.1 3.4 2.1 3 0 0 3 3 3 1 Fz domain Kringle PF00051.13 KFM13088.1 - 2.5e-23 81.9 4.9 6.4e-23 80.6 3.4 1.8 1 0 0 1 1 1 1 Kringle domain I-set PF07679.11 KFM13088.1 - 1.5e-17 63.2 0.0 2.5e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM13088.1 - 1.5e-09 37.8 0.1 3.6e-09 36.6 0.1 1.7 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFM13088.1 - 2.1e-08 34.1 0.0 5.4e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFM13088.1 - 1.2e-07 32.1 1.4 1.9e-07 31.4 0.1 2.1 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.12 KFM13088.1 - 3.4e-05 23.7 0.0 0.00013 21.8 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain TMEM154 PF15102.1 KFM13088.1 - 0.039 13.6 0.0 0.039 13.6 0.0 1.6 2 0 0 2 2 2 0 TMEM154 protein family PALP PF00291.20 KFM13090.1 - 1.3e-64 218.4 1.6 1.5e-64 218.1 1.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AIRC PF00731.15 KFM13090.1 - 0.0018 17.5 3.3 0.22 10.7 0.1 2.2 2 0 0 2 2 2 2 AIR carboxylase AlaDh_PNT_C PF01262.16 KFM13090.1 - 0.0023 17.5 0.1 0.004 16.7 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DegT_DnrJ_EryC1 PF01041.12 KFM13090.1 - 0.02 13.9 0.2 0.035 13.1 0.1 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family GIDA PF01134.17 KFM13090.1 - 0.042 12.7 0.2 0.071 11.9 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A SIS_2 PF13580.1 KFM13090.1 - 0.077 12.7 0.0 0.22 11.2 0.0 1.8 1 0 0 1 1 1 0 SIS domain Na_Ca_ex PF01699.19 KFM13091.1 - 9.4e-39 132.2 36.1 6.9e-24 84.0 8.6 3.0 3 1 0 3 3 3 2 Sodium/calcium exchanger protein Ion_trans PF00520.26 KFM13092.1 - 1.3e-48 164.8 53.0 2.2e-29 102.1 16.6 2.3 2 0 0 2 2 2 2 Ion transport protein OppC_N PF12911.2 KFM13092.1 - 0.00082 18.6 7.3 0.86 9.0 1.2 4.2 3 0 0 3 3 3 2 N-terminal TM domain of oligopeptide transport permease C DUF1474 PF07342.6 KFM13092.1 - 0.032 14.4 0.1 3.4 7.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) DUF1628 PF07790.6 KFM13092.1 - 0.12 13.1 0.1 0.92 10.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1628) DEAD PF00270.24 KFM13093.1 - 3.3e-47 160.1 0.0 8.6e-47 158.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFM13093.1 - 3.9e-20 71.5 0.0 7.8e-20 70.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 KFM13093.1 - 7.7e-20 70.4 8.0 2e-19 69.1 5.5 1.7 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.10 KFM13093.1 - 3.4e-07 30.2 2.1 1.9e-06 27.8 0.0 2.6 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 KFM13093.1 - 0.15 11.7 0.5 7.3 6.3 0.0 2.6 3 0 0 3 3 3 0 Flavivirus DEAD domain TPR_MLP1_2 PF07926.7 KFM13094.1 - 0.05 13.3 1.4 0.074 12.7 1.0 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PBP PF01161.15 KFM13095.1 - 2.5e-28 98.7 0.1 3e-28 98.5 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein SRRM_C PF15230.1 KFM13096.1 - 6.3e-24 83.8 30.9 6.3e-24 83.8 21.4 10.7 4 3 5 9 9 9 1 Serine/arginine repetitive matrix protein C-terminus Dispanin PF04505.7 KFM13098.1 - 3.2e-22 77.8 0.2 5.2e-22 77.1 0.1 1.3 1 0 0 1 1 1 1 Interferon-induced transmembrane protein DUF4190 PF13828.1 KFM13098.1 - 0.0015 17.9 4.3 0.0072 15.8 3.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4190) Claudin_3 PF06653.6 KFM13098.1 - 0.015 15.0 1.1 0.018 14.7 0.7 1.1 1 0 0 1 1 1 0 Tight junction protein, Claudin-like DUF4234 PF14018.1 KFM13098.1 - 0.5 10.1 3.6 1.6 8.5 0.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4234) AMPKBI PF04739.10 KFM13099.1 - 1.1e-29 102.3 0.4 1.7e-29 101.6 0.2 1.4 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interation domain CBM_48 PF02922.13 KFM13099.1 - 0.055 13.5 0.1 0.14 12.2 0.0 1.7 1 1 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) CNH PF00780.17 KFM13100.1 - 6.4e-60 202.9 0.0 1.4e-59 201.7 0.0 1.6 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.20 KFM13100.1 - 3.6e-56 190.2 0.0 3.6e-56 190.2 0.0 3.0 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM13100.1 - 4.7e-28 97.9 0.0 1.4e-27 96.4 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 KFM13100.1 - 9.2e-06 25.3 9.3 2.1e-05 24.1 6.4 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.24 KFM13100.1 - 0.00017 21.7 0.0 0.00073 19.7 0.0 2.2 1 0 0 1 1 1 1 PH domain Pkinase_C PF00433.19 KFM13100.1 - 0.00049 20.5 1.2 0.0014 19.0 0.8 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Seadorna_VP7 PF07387.6 KFM13100.1 - 0.00053 18.9 0.1 0.0018 17.1 0.1 1.9 1 0 0 1 1 1 1 Seadornavirus VP7 V_ATPase_I PF01496.14 KFM13100.1 - 0.00088 17.2 13.3 0.00088 17.2 9.2 5.8 1 1 4 5 5 5 1 V-type ATPase 116kDa subunit family APH PF01636.18 KFM13100.1 - 0.002 17.9 0.0 0.002 17.9 0.0 4.3 5 1 0 5 5 5 1 Phosphotransferase enzyme family DUF1601 PF07671.6 KFM13101.1 - 0.027 14.1 5.1 3.4 7.3 0.0 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1601) bZIP_2 PF07716.10 KFM13101.1 - 0.044 13.6 1.6 0.044 13.6 1.1 8.2 5 3 4 9 9 9 0 Basic region leucine zipper bZIP_1 PF00170.16 KFM13101.1 - 0.19 11.7 40.2 0.38 10.7 0.7 6.6 5 3 1 6 6 6 0 bZIP transcription factor CENP-F_leu_zip PF10473.4 KFM13101.1 - 4.4 7.1 72.2 5.9 6.7 14.0 5.3 1 1 4 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ras PF00071.17 KFM13102.1 - 2.6e-55 186.2 0.5 3.4e-55 185.8 0.4 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM13102.1 - 2.1e-16 60.5 0.2 4.8e-16 59.3 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFM13102.1 - 7.4e-16 57.8 0.2 1e-15 57.4 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFM13102.1 - 1.4e-07 31.1 0.1 2.4e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFM13102.1 - 0.0037 16.4 0.8 0.0087 15.2 0.6 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFM13102.1 - 0.0061 16.5 0.3 0.0094 15.8 0.2 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF3554 PF12074.3 KFM13103.1 - 3.4e-75 253.6 16.1 2.1e-72 244.3 2.2 6.6 7 1 1 8 8 8 2 Domain of unknown function (DUF3554) HEAT PF02985.17 KFM13103.1 - 5.9e-51 166.0 39.4 0.0039 17.1 0.0 25.8 29 0 0 29 29 29 13 HEAT repeat HEAT_2 PF13646.1 KFM13103.1 - 2.3e-49 165.5 46.7 2e-08 34.3 0.2 18.6 12 3 8 20 20 20 12 HEAT repeats HEAT_EZ PF13513.1 KFM13103.1 - 8.2e-32 108.8 51.8 0.0025 18.2 0.0 24.0 18 8 11 29 29 29 10 HEAT-like repeat CLASP_N PF12348.3 KFM13103.1 - 1.6e-22 80.0 3.3 3.4e-05 23.2 0.0 10.7 10 2 1 12 12 12 3 CLASP N terminal Vac14_Fab1_bd PF12755.2 KFM13103.1 - 3.6e-17 62.5 0.0 0.25 11.7 0.0 10.4 10 1 2 12 12 12 5 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 KFM13103.1 - 1.5e-10 41.1 5.0 0.25 11.1 0.0 8.9 9 1 0 9 9 9 3 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.4 KFM13103.1 - 1e-05 25.5 10.9 1.8 8.4 0.0 8.1 10 0 0 10 10 10 2 Parkin co-regulated protein Arm PF00514.18 KFM13103.1 - 0.3 10.9 14.6 49 3.9 0.0 9.3 9 0 0 9 9 9 0 Armadillo/beta-catenin-like repeat Ribosomal_L10 PF00466.15 KFM13104.1 - 1.2e-23 82.9 0.0 2.1e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 KFM13104.1 - 2.5e-17 63.0 3.8 2.6e-17 62.9 1.3 1.9 2 0 0 2 2 2 1 60s Acidic ribosomal protein Paxillin PF03535.8 KFM13105.1 - 1.1e-91 306.1 24.0 1.1e-91 306.1 16.6 1.8 2 0 0 2 2 2 1 Paxillin family LIM PF00412.17 KFM13105.1 - 1.9e-67 223.1 38.1 8.4e-19 67.3 1.5 4.2 4 0 0 4 4 4 4 LIM domain DUF164 PF02591.10 KFM13105.1 - 0.001 18.8 0.5 0.001 18.8 0.4 4.6 4 1 1 5 5 5 1 Putative zinc ribbon domain DUF1797 PF08796.5 KFM13105.1 - 0.21 11.4 0.3 9.1 6.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1797) SIR2 PF02146.12 KFM13106.1 - 2.2e-51 174.1 0.0 2.7e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 Sir2 family zf-C3HC4_3 PF13920.1 KFM13106.1 - 0.18 11.4 3.5 0.2 11.3 0.3 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Phospholip_A2_1 PF00068.14 KFM13107.1 - 6.6e-42 142.4 16.2 7.5e-42 142.2 11.2 1.0 1 0 0 1 1 1 1 Phospholipase A2 Parvo_coat_N PF08398.5 KFM13107.1 - 0.0023 17.6 0.0 0.0057 16.4 0.0 1.6 1 1 0 1 1 1 1 Parvovirus coat protein VP1 RRM_1 PF00076.17 KFM13108.1 - 2.8e-33 113.3 2.4 3.7e-17 61.7 0.6 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM13108.1 - 2.4e-28 97.8 1.3 1.4e-14 53.7 0.3 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM13108.1 - 4.2e-13 48.9 0.8 4.9e-06 26.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NID PF07292.8 KFM13108.1 - 0.0018 18.2 0.4 0.85 9.7 0.0 2.3 2 0 0 2 2 2 2 Nmi/IFP 35 domain (NID) Med8 PF10232.4 KFM13108.1 - 0.056 12.9 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 CSD PF00313.17 KFM13108.1 - 0.13 12.0 1.0 2.7 7.8 0.2 2.3 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain DUF2136 PF09907.4 KFM13108.1 - 0.15 12.1 0.1 0.25 11.4 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2136) COX6A PF02046.10 KFM13109.1 - 3.4e-28 97.8 0.0 3.7e-28 97.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa UPF0203 PF05254.7 KFM13110.1 - 2.3e-27 94.6 0.3 2.5e-27 94.4 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) CHCH PF06747.8 KFM13110.1 - 0.012 15.5 1.5 3.2 7.7 0.1 2.3 2 0 0 2 2 2 0 CHCH domain UCR_hinge PF02320.11 KFM13110.1 - 0.076 12.9 1.6 0.87 9.5 1.1 2.0 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein COX17 PF05051.8 KFM13110.1 - 0.085 12.8 0.4 0.21 11.6 0.3 1.6 1 1 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) COX6B PF02297.12 KFM13110.1 - 0.14 12.1 2.7 0.24 11.4 1.8 1.4 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb Glu-tRNAGln PF02686.10 KFM13111.1 - 1.4e-16 60.0 0.1 2e-16 59.5 0.1 1.3 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit Dynein_light PF01221.13 KFM13112.1 - 9.2e-26 89.6 0.4 9.5e-26 89.6 0.3 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ubie_methyltran PF01209.13 KFM13113.1 - 4.8e-90 300.7 0.0 6.1e-90 300.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 KFM13113.1 - 1e-17 64.3 0.0 2.1e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFM13113.1 - 1.1e-15 57.5 0.0 2.6e-14 53.0 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFM13113.1 - 2.1e-11 44.0 0.0 3.8e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFM13113.1 - 1.2e-08 35.4 0.0 1.2e-06 29.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFM13113.1 - 1.9e-08 34.6 0.0 1.2e-07 32.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFM13113.1 - 2.5e-08 33.7 0.0 3.7e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFM13113.1 - 2.8e-07 30.5 0.0 5.3e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KFM13113.1 - 0.0068 16.0 0.0 0.022 14.3 0.0 1.8 2 0 0 2 2 2 1 Hypothetical methyltransferase UPF0020 PF01170.13 KFM13113.1 - 0.0087 15.6 0.0 0.019 14.5 0.0 1.6 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_3 PF01596.12 KFM13113.1 - 0.098 11.6 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase Dynein_light PF01221.13 KFM13114.1 - 1.4e-36 124.3 1.3 1.5e-36 124.2 0.9 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.13 KFM13114.1 - 0.061 13.6 0.0 0.064 13.5 0.0 1.2 1 0 0 1 1 1 0 Ground-like domain CotJB PF12652.2 KFM13114.1 - 0.12 12.4 0.1 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 CotJB protein Peptidase_M14 PF00246.19 KFM13115.1 - 1.5e-73 247.8 0.4 2.7e-73 246.9 0.1 1.5 2 0 0 2 2 2 1 Zinc carboxypeptidase F5_F8_type_C PF00754.20 KFM13115.1 - 7.3e-27 93.7 0.7 1.4e-26 92.8 0.1 1.8 2 0 0 2 2 2 1 F5/8 type C domain CarboxypepD_reg PF13620.1 KFM13115.1 - 5.3e-12 45.6 0.0 1.3e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 KFM13115.1 - 9.8e-05 22.3 0.0 0.00028 20.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4480) AstE_AspA PF04952.9 KFM13115.1 - 0.17 10.7 0.0 0.33 9.7 0.0 1.4 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Acetyltransf_1 PF00583.19 KFM13116.1 - 4.5e-14 52.2 0.6 1e-13 51.0 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KFM13116.1 - 5.9e-12 45.7 0.1 1.1e-11 44.9 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KFM13116.1 - 1.4e-08 34.7 0.0 2.2e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KFM13116.1 - 1.4e-06 28.2 0.0 2.4e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFM13116.1 - 5.6e-06 26.2 0.1 0.00037 20.3 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KFM13116.1 - 3.6e-05 23.5 0.0 6.7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 KFM13116.1 - 0.00013 22.1 0.3 0.0012 18.9 0.0 2.3 1 1 2 4 4 4 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFM13116.1 - 0.028 14.1 0.1 0.071 12.8 0.1 1.6 1 0 0 1 1 1 0 FR47-like protein DUF4381 PF14316.1 KFM13116.1 - 0.11 12.5 1.1 0.19 11.8 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Vps16_N PF04841.8 KFM13117.1 - 2.9e-120 401.5 0.0 3.6e-120 401.2 0.0 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 KFM13117.1 - 1.4e-93 313.3 0.5 2.5e-93 312.5 0.4 1.4 1 0 0 1 1 1 1 Vps16, C-terminal region Nt_Gln_amidase PF09764.4 KFM13117.1 - 0.066 12.5 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 N-terminal glutamine amidase Iso_dh PF00180.15 KFM13118.1 - 4e-75 252.9 0.2 4.8e-75 252.6 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase AAA_3 PF07726.6 KFM13118.1 - 0.099 12.2 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CENP-F_leu_zip PF10473.4 KFM13120.1 - 0.0021 17.8 21.8 0.0078 16.0 15.1 1.7 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MscS_porin PF12795.2 KFM13120.1 - 0.0028 16.9 13.5 0.0032 16.8 9.4 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Atg14 PF10186.4 KFM13120.1 - 0.0045 15.9 14.1 0.0052 15.7 9.8 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 WEMBL PF05701.6 KFM13120.1 - 0.0067 14.9 22.3 0.0071 14.8 15.4 1.0 1 0 0 1 1 1 1 Weak chloroplast movement under blue light CCDC-167 PF15188.1 KFM13120.1 - 0.0099 15.8 3.9 0.0099 15.8 2.7 2.5 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 167 Reo_sigmaC PF04582.7 KFM13120.1 - 0.011 14.9 2.4 0.013 14.6 1.6 1.0 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Spc7 PF08317.6 KFM13120.1 - 0.025 13.2 13.6 0.033 12.8 9.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein ADIP PF11559.3 KFM13120.1 - 0.027 14.3 16.4 0.037 13.9 11.3 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding PhaP_Bmeg PF09602.5 KFM13120.1 - 0.056 13.2 8.4 0.068 13.0 5.8 1.1 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) MbeD_MobD PF04899.7 KFM13120.1 - 0.061 13.2 8.3 1 9.3 0.0 3.0 2 1 1 3 3 3 0 MbeD/MobD like Fmp27_WPPW PF10359.4 KFM13120.1 - 0.073 11.4 11.2 0.091 11.1 7.8 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4200 PF13863.1 KFM13120.1 - 0.094 12.6 23.2 0.1 12.5 2.6 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) bZIP_1 PF00170.16 KFM13120.1 - 0.1 12.5 18.4 0.28 11.1 1.7 3.3 2 2 1 3 3 3 0 bZIP transcription factor LRS4 PF10422.4 KFM13120.1 - 0.26 10.6 9.1 0.39 10.0 6.3 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Mod_r PF07200.8 KFM13120.1 - 0.36 10.7 18.5 1.6 8.6 6.3 2.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Bap31 PF05529.7 KFM13120.1 - 0.4 10.1 18.9 0.3 10.5 2.1 2.1 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like DUF869 PF05911.6 KFM13120.1 - 0.4 8.8 17.9 0.42 8.7 12.4 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Exonuc_VII_L PF02601.10 KFM13120.1 - 0.74 8.9 10.2 0.85 8.7 7.1 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit WXG100 PF06013.7 KFM13120.1 - 0.79 9.7 7.1 0.25 11.3 1.1 2.4 1 1 1 2 2 2 0 Proteins of 100 residues with WXG Bacillus_HBL PF05791.6 KFM13120.1 - 0.88 8.9 10.5 0.12 11.7 3.1 2.0 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF812 PF05667.6 KFM13120.1 - 1.1 7.7 18.5 1.2 7.5 12.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Prefoldin_2 PF01920.15 KFM13120.1 - 1.2 8.9 21.0 0.04 13.6 2.0 3.0 2 1 0 2 2 2 0 Prefoldin subunit HisKA_3 PF07730.8 KFM13120.1 - 1.5 9.2 5.6 0.64 10.4 0.7 2.3 1 1 1 2 2 2 0 Histidine kinase FlxA PF14282.1 KFM13120.1 - 1.5 8.7 15.7 22 5.0 6.6 2.2 1 1 0 1 1 1 0 FlxA-like protein Uds1 PF15456.1 KFM13120.1 - 1.8 8.5 14.6 3.3 7.7 9.9 1.6 1 1 1 2 2 2 0 Up-regulated During Septation bZIP_2 PF07716.10 KFM13120.1 - 1.9 8.3 20.6 0.89 9.4 0.3 3.3 3 0 0 3 3 3 0 Basic region leucine zipper AATF-Che1 PF13339.1 KFM13120.1 - 2 8.5 11.4 3.6 7.7 7.9 1.4 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF342 PF03961.8 KFM13120.1 - 2.3 6.5 11.1 3.3 6.0 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TSC22 PF01166.13 KFM13120.1 - 2.7 8.0 13.0 2.5 8.1 1.0 2.7 2 2 0 2 2 2 0 TSC-22/dip/bun family Nup54 PF13874.1 KFM13120.1 - 2.7 7.6 12.4 3.1 7.4 4.3 2.1 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Mnd1 PF03962.10 KFM13120.1 - 2.9 7.5 15.9 14 5.3 10.9 1.9 1 1 0 1 1 1 0 Mnd1 family NYD-SP28_assoc PF14775.1 KFM13120.1 - 3 7.5 10.4 2.4 7.8 0.0 3.2 3 0 0 3 3 3 0 Sperm tail C-terminal domain DUF4407 PF14362.1 KFM13120.1 - 3.3 6.5 10.2 4.4 6.1 7.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF948 PF06103.6 KFM13120.1 - 4 7.3 5.5 2.2 8.2 1.0 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Seryl_tRNA_N PF02403.17 KFM13120.1 - 4.1 7.4 17.6 0.58 10.1 2.1 2.5 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Ax_dynein_light PF10211.4 KFM13120.1 - 4.2 7.1 17.5 0.16 11.8 4.1 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain SpecificRecomb PF10136.4 KFM13120.1 - 4.7 5.1 6.1 5.2 4.9 4.3 1.0 1 0 0 1 1 1 0 Site-specific recombinase TMPIT PF07851.8 KFM13120.1 - 5.3 6.0 10.2 6.3 5.7 7.1 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF1640 PF07798.6 KFM13120.1 - 5.9 6.8 16.7 17 5.3 5.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) DUF972 PF06156.8 KFM13120.1 - 6.3 7.2 16.2 4.6 7.6 1.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF904 PF06005.7 KFM13120.1 - 6.4 7.1 19.9 7.5e+02 0.5 13.8 3.0 1 1 0 1 1 1 0 Protein of unknown function (DUF904) APG6 PF04111.7 KFM13120.1 - 6.4 5.7 18.6 7.7 5.4 12.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 TPR_MLP1_2 PF07926.7 KFM13120.1 - 7 6.4 20.1 14 5.4 12.7 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.7 KFM13120.1 - 7.2 6.4 10.0 0.84 9.4 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Borrelia_P83 PF05262.6 KFM13120.1 - 7.5 4.7 14.5 7.8 4.6 10.1 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF724 PF05266.9 KFM13120.1 - 7.5 6.1 18.9 4 7.0 9.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF4140 PF13600.1 KFM13120.1 - 7.8 7.0 14.0 6.4 7.2 1.0 2.4 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) Pepsin-I3 PF06394.8 KFM13120.1 - 8.1 6.1 7.9 1.2 8.8 1.4 2.3 2 1 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain DUF3450 PF11932.3 KFM13120.1 - 8.2 5.6 17.3 7.3 5.7 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) CAP_GLY PF01302.20 KFM13121.1 - 4.9e-24 83.8 2.2 6.2e-24 83.4 1.5 1.1 1 0 0 1 1 1 1 CAP-Gly domain EMP70 PF02990.11 KFM13123.1 - 1.4e-214 713.3 8.5 1.7e-214 713.1 5.9 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 RRM_1 PF00076.17 KFM13124.1 - 1.3e-23 82.4 0.1 1.9e-23 81.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM1CTR PF08081.6 KFM13124.1 - 1e-22 79.5 18.9 1e-22 79.5 13.1 10.0 5 3 5 10 10 10 1 RBM1CTR (NUC064) family RRM_6 PF14259.1 KFM13124.1 - 7.8e-17 61.0 0.0 1.2e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM13124.1 - 1.7e-11 43.7 0.0 2.7e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RhoGEF PF00621.15 KFM13125.1 - 1.2e-33 116.4 1.6 1.2e-33 116.4 1.1 2.7 2 1 0 2 2 2 1 RhoGEF domain SH3_9 PF14604.1 KFM13125.1 - 4.1e-17 61.5 0.2 9.2e-17 60.3 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFM13125.1 - 1.6e-16 59.4 0.5 3.2e-16 58.5 0.3 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM13125.1 - 7.3e-15 54.0 0.3 1.4e-14 53.2 0.2 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 KFM13125.1 - 1.1e-11 44.8 0.0 2.5e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 PH domain CH PF00307.26 KFM13125.1 - 7.7e-11 41.9 0.1 2.4e-10 40.4 0.0 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFM13125.1 - 1.7e-05 24.3 0.0 6.3e-05 22.5 0.0 1.9 1 0 0 1 1 1 1 CAMSAP CH domain FlgN PF05130.7 KFM13125.1 - 0.037 14.2 10.2 5.7 7.1 0.3 3.5 3 0 0 3 3 3 0 FlgN protein MutS_III PF05192.13 KFM13125.1 - 0.074 12.8 5.6 1.2 8.8 0.2 3.1 2 1 0 2 2 2 0 MutS domain III Nsp1_C PF05064.8 KFM13125.1 - 0.14 11.7 11.8 0.033 13.8 1.2 3.8 4 1 1 5 5 5 0 Nsp1-like C-terminal region DUF745 PF05335.8 KFM13125.1 - 1.9 7.9 6.7 0.98 8.9 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF745) IncA PF04156.9 KFM13125.1 - 2.7 7.5 20.4 1.6 8.3 2.8 3.5 3 0 0 3 3 3 0 IncA protein DUF972 PF06156.8 KFM13125.1 - 4.3 7.7 14.0 2.3 8.6 2.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF972) OmpH PF03938.9 KFM13125.1 - 9.4 6.1 9.7 4.7 7.1 0.2 3.0 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) TNF PF00229.13 KFM13126.1 - 8.1e-31 106.2 0.3 1.5e-30 105.3 0.1 1.5 2 0 0 2 2 2 1 TNF(Tumour Necrosis Factor) family C1q PF00386.16 KFM13126.1 - 0.026 14.5 0.3 0.026 14.5 0.2 2.9 3 1 1 4 4 4 0 C1q domain Orthopox_A36R PF05950.6 KFM13126.1 - 0.11 12.3 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 Orthopoxvirus A36R protein Neur_chan_memb PF02932.11 KFM13126.1 - 0.21 11.4 6.9 1.2 8.9 4.8 1.9 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Vg_Tdu PF07545.9 KFM13127.1 - 1.8e-20 72.0 0.2 3.7e-20 71.0 0.2 1.5 1 0 0 1 1 1 1 Vestigial/Tondu family RRM_1 PF00076.17 KFM13128.1 - 6.1e-16 57.8 0.0 1.1e-06 28.2 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM13128.1 - 2.8e-12 46.2 0.0 3.8e-10 39.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM13128.1 - 1.6e-09 37.6 0.0 0.00091 19.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) 7tm_1 PF00001.16 KFM13129.1 - 7.6e-59 198.9 14.3 1.1e-58 198.3 9.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM13129.1 - 2.9e-11 43.0 14.3 4.6e-11 42.3 9.9 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 KFM13129.1 - 5.1e-09 35.6 14.7 6.7e-09 35.2 10.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.4 KFM13129.1 - 7.2e-05 22.0 12.7 0.00011 21.4 8.8 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx TAS2R PF05296.8 KFM13129.1 - 0.00045 19.1 3.9 0.00045 19.1 2.7 2.0 2 0 0 2 2 2 1 Mammalian taste receptor protein (TAS2R) DUF912 PF06024.7 KFM13129.1 - 3.9 7.5 5.7 2.7 8.1 1.3 2.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) 7tm_2 PF00002.19 KFM13130.1 - 2.7e-49 167.4 23.0 3.5e-49 167.0 15.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.16 KFM13130.1 - 2.2e-14 53.2 2.8 3.9e-14 52.4 1.9 1.4 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain FA_desaturase PF00487.19 KFM13130.1 - 0.27 10.6 17.6 0.31 10.4 5.2 2.3 2 0 0 2 2 2 0 Fatty acid desaturase LIM PF00412.17 KFM13132.1 - 3e-46 155.2 77.1 1.4e-12 47.4 7.3 5.1 5 0 0 5 5 5 5 LIM domain Ureidogly_hydro PF04115.7 KFM13132.1 - 0.0036 16.6 0.0 0.59 9.4 0.0 2.9 1 1 1 2 2 2 1 Ureidoglycolate hydrolase zf-RING_6 PF14835.1 KFM13132.1 - 0.024 14.4 1.7 0.024 14.4 1.2 5.4 5 1 0 5 5 5 0 zf-RING of BARD1-type protein Sgf11 PF08209.6 KFM13132.1 - 0.063 12.6 0.4 0.063 12.6 0.3 9.3 11 1 1 12 12 12 0 Sgf11 (transcriptional regulation protein) Na_H_Exchanger PF00999.16 KFM13133.1 - 4.5e-75 252.5 34.5 1.1e-74 251.3 23.9 1.5 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family MMgT PF10270.4 KFM13134.1 - 3.8e-15 56.2 0.0 5.7e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Membrane magnesium transporter INT_SG_DDX_CT_C PF15300.1 KFM13135.1 - 5e-31 105.9 3.0 9.2e-31 105.1 1.3 2.1 2 0 0 2 2 2 1 INTS6/SAGE1/DDX26B/CT45 C-terminus Motile_Sperm PF00635.21 KFM13136.1 - 6.6e-17 61.1 0.2 1.1e-16 60.4 0.1 1.4 1 1 0 1 1 1 1 MSP (Major sperm protein) domain Isy1 PF06246.7 KFM13136.1 - 0.032 13.6 0.0 0.034 13.5 0.0 1.1 1 0 0 1 1 1 0 Isy1-like splicing family FAM101 PF15068.1 KFM13137.1 - 0.15 11.5 2.8 0.16 11.4 0.5 2.1 2 0 0 2 2 2 0 FAM101 family DUF1582 PF07621.6 KFM13137.1 - 0.45 10.5 5.9 9.4 6.4 3.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1582) DUF566 PF04484.7 KFM13137.1 - 7.8 5.8 13.0 3.8 6.9 0.3 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF566) DUF1582 PF07621.6 KFM13138.1 - 1.3 9.1 6.8 10 6.2 2.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1582) Pribosyltran PF00156.22 KFM13139.1 - 5.7e-07 29.3 0.0 1.6e-06 27.8 0.0 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain zf-HC5HC2H PF13771.1 KFM13140.1 - 5.8e-35 119.3 31.3 1.2e-18 66.9 6.3 3.5 4 0 0 4 4 4 2 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 KFM13140.1 - 1.3e-12 47.6 27.9 2.2e-06 27.6 8.7 2.8 2 1 1 3 3 3 2 PHD-zinc-finger like domain zf-Apc11 PF12861.2 KFM13140.1 - 0.26 11.1 14.4 3.1 7.7 0.3 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger Glypican PF01153.14 KFM13141.1 - 2.7e-223 742.6 5.7 3e-223 742.4 4.0 1.0 1 0 0 1 1 1 1 Glypican Sulfotransfer_2 PF03567.9 KFM13142.1 - 3.3e-48 164.5 1.0 3.3e-48 164.5 0.7 1.5 2 0 0 2 2 2 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.6 KFM13142.1 - 0.0016 17.2 0.6 0.072 11.7 0.2 2.1 2 0 0 2 2 2 2 Galactose-3-O-sulfotransferase Topoisom_I_N PF02919.10 KFM13142.1 - 0.31 10.2 6.0 0.59 9.3 4.2 1.4 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment zf-CCCH PF00642.19 KFM13143.1 - 1.3e-11 43.8 21.4 0.00052 19.6 0.3 4.7 4 1 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ras PF00071.17 KFM13144.1 - 4.7e-37 126.8 0.0 5.3e-37 126.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM13144.1 - 1.4e-11 44.8 0.0 2.9e-11 43.8 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 KFM13144.1 - 1.4e-06 27.9 0.0 2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 KFM13144.1 - 5.6e-05 22.4 0.0 6.6e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.13 KFM13144.1 - 0.0062 15.8 0.0 0.0083 15.4 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B TPP_enzyme_M PF00205.17 KFM13144.1 - 0.062 13.0 0.0 0.083 12.6 0.0 1.2 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain FERM_C PF09380.5 KFM13145.1 - 1.9e-27 95.2 0.5 3.9e-27 94.3 0.3 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.13 KFM13145.1 - 2.2e-15 56.9 0.1 4e-15 56.1 0.1 1.4 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.5 KFM13145.1 - 8.1e-13 48.2 4.0 9.2e-13 48.0 0.1 2.9 2 1 0 2 2 2 1 FERM N-terminal domain FA PF08736.6 KFM13145.1 - 1.1e-12 47.5 3.1 1.1e-12 47.5 2.2 2.1 2 0 0 2 2 2 1 FERM adjacent (FA) Pkinase PF00069.20 KFM13147.1 - 6.9e-72 241.7 0.0 8e-72 241.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM13147.1 - 2.9e-54 183.8 0.0 3.6e-54 183.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM13147.1 - 0.00019 20.4 0.0 0.0012 17.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KFM13147.1 - 0.0064 16.2 0.0 1.3 8.7 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family DUF4288 PF14119.1 KFM13147.1 - 0.079 13.0 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) IL6Ra-bind PF09240.5 KFM13148.1 - 9.4e-19 67.4 0.4 2.2e-18 66.2 0.1 1.7 2 0 0 2 2 2 1 Interleukin-6 receptor alpha chain, binding EpoR_lig-bind PF09067.5 KFM13148.1 - 6.3e-07 29.3 0.2 1.6e-06 28.0 0.1 1.7 1 0 0 1 1 1 1 Erythropoietin receptor, ligand binding Tissue_fac PF01108.12 KFM13148.1 - 9.2e-05 22.1 3.3 0.073 12.8 0.2 2.9 2 1 0 2 2 2 2 Tissue factor fn3 PF00041.16 KFM13148.1 - 0.00082 19.4 1.1 0.069 13.2 0.1 2.6 2 1 0 2 2 2 1 Fibronectin type III domain TMEM154 PF15102.1 KFM13148.1 - 0.015 15.0 0.1 0.035 13.8 0.1 1.6 1 0 0 1 1 1 0 TMEM154 protein family Ded_cyto PF06920.8 KFM13149.1 - 7.3e-66 220.8 7.6 7.9e-66 220.7 0.7 3.8 4 0 0 4 4 4 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 KFM13149.1 - 9.6e-57 191.5 0.1 3e-56 189.9 0.0 2.0 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.3 KFM13149.1 - 1.2e-32 111.6 2.1 4.5e-32 109.7 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3398) PH PF00169.24 KFM13149.1 - 2.2e-10 40.6 1.2 1.2e-09 38.2 0.5 2.4 2 0 0 2 2 2 1 PH domain WD40 PF00400.27 KFM13150.1 - 7.8e-36 120.6 5.1 6.3e-07 29.0 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat BBS2_Mid PF14783.1 KFM13150.1 - 0.037 13.8 0.1 1.8 8.3 0.0 3.3 2 2 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region SMN PF06003.7 KFM13150.1 - 2.4 7.1 11.4 1 8.4 5.4 2.1 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) Kelch_1 PF01344.20 KFM13151.1 - 4.9e-56 186.0 7.3 1.2e-11 43.9 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 KFM13151.1 - 1.3e-36 123.2 2.5 1e-06 28.6 0.1 6.6 2 1 4 6 6 6 5 Kelch motif BACK PF07707.10 KFM13151.1 - 2.8e-27 94.5 0.0 5.9e-27 93.5 0.0 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.26 KFM13151.1 - 7.6e-25 87.0 0.3 3.7e-24 84.8 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.1 KFM13151.1 - 7.6e-25 86.4 2.4 0.00011 22.1 0.0 6.7 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.10 KFM13151.1 - 5.9e-24 82.8 5.3 3.1e-05 23.5 0.0 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.1 KFM13151.1 - 1.1e-21 76.3 1.0 0.00078 19.1 0.0 5.7 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.1 KFM13151.1 - 7.9e-12 44.8 14.2 0.0044 16.9 0.2 5.7 5 0 0 5 5 5 4 Kelch motif DUF1075 PF06388.6 KFM13152.1 - 1.8e-40 137.9 0.5 2e-40 137.8 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1075) NB PF04159.8 KFM13152.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 NB glycoprotein SNF PF00209.13 KFM13153.1 - 1.8e-196 653.6 42.2 2.3e-196 653.3 29.2 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Caveolin PF01146.12 KFM13153.1 - 0.0096 15.5 2.9 0.0096 15.5 2.0 2.4 2 0 0 2 2 2 1 Caveolin LRR_8 PF13855.1 KFM13154.1 - 1.6e-31 107.8 36.4 1.6e-14 53.3 5.8 4.0 1 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KFM13154.1 - 1.7e-21 75.3 53.2 1.8e-07 30.5 0.6 5.1 2 2 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM13154.1 - 9.9e-18 61.4 36.4 0.0084 15.9 0.1 7.4 7 0 0 7 7 7 7 Leucine Rich Repeat LRR_5 PF13306.1 KFM13154.1 - 4.3e-12 45.8 2.0 3.4e-10 39.7 0.5 2.0 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) LRR_7 PF13504.1 KFM13154.1 - 2.4e-07 29.8 34.2 0.72 10.3 0.3 7.7 7 0 0 7 7 7 6 Leucine rich repeat LRR_6 PF13516.1 KFM13154.1 - 1.5e-05 24.5 35.9 0.68 10.1 0.4 7.3 6 1 1 7 7 7 5 Leucine Rich repeat LRR_9 PF14580.1 KFM13154.1 - 0.0036 16.8 2.2 0.17 11.4 0.1 2.1 1 1 1 2 2 2 2 Leucine-rich repeat CH PF00307.26 KFM13155.1 - 1.1e-82 273.1 1.0 2.5e-22 78.9 0.0 4.8 5 0 0 5 5 5 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 KFM13155.1 - 8.2e-13 48.2 0.2 2.8e-12 46.5 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KFM13155.1 - 7.2e-08 31.2 2.4 1.3e-05 24.1 0.4 3.0 2 0 0 2 2 2 2 EF hand CAMSAP_CH PF11971.3 KFM13155.1 - 1.1e-06 28.1 0.1 2.8e-05 23.6 0.0 2.8 3 0 0 3 3 3 1 CAMSAP CH domain EF-hand_5 PF13202.1 KFM13155.1 - 0.00014 21.0 4.5 0.00041 19.5 0.0 3.6 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.1 KFM13155.1 - 0.0047 16.7 0.3 0.061 13.2 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 KFM13155.1 - 0.011 15.2 0.6 0.062 12.9 0.1 2.6 2 0 0 2 2 2 0 EF-hand domain pair MPLKIP PF15502.1 KFM13156.1 - 0.51 11.0 10.2 0.62 10.7 7.0 1.0 1 0 0 1 1 1 0 M-phase-specific PLK1-interacting protein LRR_4 PF12799.2 KFM13157.1 - 1.6e-24 85.0 20.6 1.6e-07 30.7 3.5 5.5 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM13157.1 - 2.8e-23 81.4 13.2 2.9e-09 36.5 1.6 3.6 1 1 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 KFM13157.1 - 2e-18 63.5 20.1 0.024 14.6 0.2 8.9 8 0 0 8 8 8 6 Leucine Rich Repeat CH PF00307.26 KFM13157.1 - 3.8e-10 39.7 0.0 1.2e-09 38.2 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain LRR_7 PF13504.1 KFM13157.1 - 4e-09 35.1 16.1 2.8 8.5 0.2 8.3 8 0 0 8 8 8 2 Leucine rich repeat CAMSAP_CH PF11971.3 KFM13157.1 - 0.00073 19.1 0.0 0.0028 17.2 0.0 2.0 2 0 0 2 2 2 1 CAMSAP CH domain CDC24 PF06395.6 KFM13157.1 - 0.0047 16.9 0.0 0.012 15.6 0.0 1.7 1 0 0 1 1 1 1 CDC24 Calponin LRR_6 PF13516.1 KFM13157.1 - 0.01 15.8 17.2 29 5.1 0.3 7.0 6 1 1 7 7 7 0 Leucine Rich repeat IL6Ra-bind PF09240.5 KFM13158.1 - 1.7e-28 98.6 0.0 5.1e-28 97.1 0.0 1.8 2 0 0 2 2 2 1 Interleukin-6 receptor alpha chain, binding fn3 PF00041.16 KFM13158.1 - 2.4e-08 34.0 0.1 0.00048 20.2 0.0 3.0 3 0 0 3 3 3 2 Fibronectin type III domain EpoR_lig-bind PF09067.5 KFM13158.1 - 7.7e-05 22.6 0.2 0.00023 21.1 0.0 1.9 2 0 0 2 2 2 1 Erythropoietin receptor, ligand binding SusE PF14292.1 KFM13158.1 - 0.019 14.8 0.0 0.054 13.3 0.0 1.7 2 0 0 2 2 2 0 SusE outer membrane protein 7tm_1 PF00001.16 KFM13159.1 - 1.2e-67 227.7 13.8 1.7e-67 227.2 9.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM13159.1 - 6.6e-13 48.4 14.1 1.8e-12 46.9 9.8 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM13159.1 - 0.001 18.2 13.1 0.001 18.2 9.1 2.4 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx RseC_MucC PF04246.7 KFM13159.1 - 0.046 13.2 0.2 0.046 13.2 0.2 2.0 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Pox_P21 PF05313.7 KFM13159.1 - 2 7.6 10.0 0.041 13.1 0.7 2.6 3 0 0 3 3 3 0 Poxvirus P21 membrane protein GDPD PF03009.12 KFM13160.1 - 4.6e-22 78.7 0.0 1.7e-21 76.9 0.0 1.8 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Guanylate_kin PF00625.16 KFM13161.1 - 5.6e-57 192.1 0.1 8.3e-57 191.5 0.1 1.3 1 0 0 1 1 1 1 Guanylate kinase PDZ PF00595.19 KFM13161.1 - 8e-53 176.5 10.6 8.8e-22 77.0 0.3 3.4 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) PDZ_assoc PF10600.4 KFM13161.1 - 5.4e-28 97.0 4.0 1e-27 96.1 2.8 1.5 1 0 0 1 1 1 1 PDZ-associated domain of NMDA receptors PDZ_2 PF13180.1 KFM13161.1 - 3.3e-14 52.5 2.3 2.2e-05 24.2 0.1 3.5 3 0 0 3 3 3 3 PDZ domain MAGUK_N_PEST PF10608.4 KFM13161.1 - 2.5e-09 37.3 0.0 6.2e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Polyubiquitination (PEST) N-terminal domain of MAGUK SH3_1 PF00018.23 KFM13161.1 - 1.7e-08 33.7 0.0 3.8e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFM13161.1 - 1.3e-07 31.0 0.0 3.4e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KFM13161.1 - 2.2e-05 23.9 0.1 0.00018 20.9 0.0 2.5 3 0 0 3 3 3 1 Variant SH3 domain SPO22 PF08631.5 KFM13162.1 - 1.5e-57 194.7 5.7 2.9e-57 193.8 1.5 3.4 4 1 0 4 4 4 2 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.1 KFM13162.1 - 4.9e-09 36.0 6.4 0.00047 20.0 0.4 5.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFM13162.1 - 3e-06 26.7 7.7 0.005 16.6 0.1 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFM13162.1 - 2.1e-05 23.9 4.3 0.028 14.0 0.1 5.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 KFM13162.1 - 9.3e-05 21.9 7.6 0.0001 21.8 0.8 4.1 4 1 1 5 5 5 1 TPR repeat TPR_19 PF14559.1 KFM13162.1 - 0.00024 21.3 0.4 0.022 15.1 0.0 4.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFM13162.1 - 0.0018 17.9 0.8 0.026 14.2 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFM13162.1 - 0.012 16.1 0.4 3.1 8.6 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFM13162.1 - 0.038 14.6 0.2 1 10.1 0.0 3.7 4 1 0 4 4 4 0 Tetratricopeptide repeat RRM_1 PF00076.17 KFM13163.1 - 2.6e-18 65.4 0.0 3.2e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM13163.1 - 9.4e-14 51.0 0.0 1.4e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM13163.1 - 1.4e-13 50.5 0.0 1.8e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) AA_permease_2 PF13520.1 KFM13164.1 - 2.2e-50 171.4 25.6 2.2e-50 171.4 17.8 2.1 1 1 0 2 2 2 1 Amino acid permease AA_permease PF00324.16 KFM13164.1 - 1.6e-35 122.3 26.9 1.6e-35 122.3 18.7 2.1 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.1 KFM13164.1 - 1.1e-23 82.7 6.0 1.1e-23 82.7 4.1 4.2 4 0 0 4 4 4 1 C-terminus of AA_permease Bombesin PF02044.12 KFM13165.1 - 0.053 12.9 1.6 0.087 12.2 1.1 1.3 1 0 0 1 1 1 0 Bombesin-like peptide PX PF00787.19 KFM13166.1 - 2.2e-21 75.7 0.2 2.4e-21 75.6 0.2 1.1 1 0 0 1 1 1 1 PX domain PA26 PF04636.8 KFM13167.1 - 3.6e-171 569.8 0.1 4.5e-171 569.5 0.1 1.1 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) CMD PF02627.15 KFM13167.1 - 0.0058 16.4 0.0 0.016 15.0 0.0 1.8 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family IL6Ra-bind PF09240.5 KFM13168.1 - 3.5e-20 71.9 0.1 6.8e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding EpoR_lig-bind PF09067.5 KFM13168.1 - 2.2e-07 30.8 0.1 4.7e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 Erythropoietin receptor, ligand binding fn3 PF00041.16 KFM13168.1 - 2.8e-07 30.5 1.8 2.8e-07 30.5 1.3 2.3 3 1 0 3 3 3 1 Fibronectin type III domain Adeno_E3_CR1 PF02440.10 KFM13168.1 - 0.2 11.1 1.8 0.29 10.6 0.1 2.2 2 0 0 2 2 2 0 Adenovirus E3 region protein CR1 COesterase PF00135.23 KFM13169.1 - 9.9e-188 625.1 0.0 1.2e-187 624.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFM13169.1 - 3e-05 23.7 0.0 9e-05 22.1 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Connexin PF00029.14 KFM13170.1 - 9.9e-49 163.8 1.0 9.9e-49 163.8 0.7 2.4 2 1 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 KFM13170.1 - 4.8e-31 106.3 7.3 1.7e-30 104.6 5.1 2.0 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain COX6A PF02046.10 KFM13170.1 - 1.2 9.0 3.4 5 7.0 0.7 2.4 1 1 0 2 2 2 0 Cytochrome c oxidase subunit VIa Connexin PF00029.14 KFM13171.1 - 2.6e-48 162.5 0.1 3.9e-48 161.9 0.1 1.2 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 KFM13171.1 - 4.6e-24 83.9 0.2 1.2e-23 82.6 0.1 1.7 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain zf-FCS PF06467.9 KFM13172.1 - 1.2e-70 232.8 115.1 7.9e-10 38.2 3.2 10.8 10 1 1 11 11 11 10 MYM-type Zinc finger with FCS sequence motif DUF3504 PF12012.3 KFM13172.1 - 8.3e-70 234.0 0.3 1.7e-69 232.9 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3504) Arc_trans_TRASH PF08394.5 KFM13172.1 - 3.7e-05 23.7 7.6 3.7e-05 23.7 5.3 8.6 10 2 0 10 10 10 2 Archaeal TRASH domain YHS PF04945.8 KFM13172.1 - 0.11 12.3 44.5 1.2 9.0 0.2 9.0 10 0 0 10 10 10 0 YHS domain RRM_1 PF00076.17 KFM13173.1 - 2.6e-31 107.0 0.1 1.5e-15 56.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NOPS PF08075.6 KFM13173.1 - 1.7e-29 101.9 2.1 5.2e-29 100.4 1.4 1.9 1 0 0 1 1 1 1 NOPS (NUC059) domain RRM_6 PF14259.1 KFM13173.1 - 3.9e-21 74.7 0.0 1.8e-09 37.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM13173.1 - 2.5e-12 46.4 0.0 7.4e-06 25.7 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3256 PF11644.3 KFM13173.1 - 0.23 10.9 0.7 0.37 10.2 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3256) Aldedh PF00171.17 KFM13173.1 - 3.5 5.8 6.4 4.9 5.3 4.4 1.1 1 0 0 1 1 1 0 Aldehyde dehydrogenase family CAF-1_p150 PF11600.3 KFM13173.1 - 7.9 5.7 32.8 18 4.6 22.7 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CHORD PF04968.7 KFM13174.1 - 1.4e-53 178.9 21.0 3.6e-28 97.5 3.1 2.5 3 0 0 3 3 3 2 CHORD CS PF04969.11 KFM13174.1 - 4.8e-15 55.8 0.5 7.6e-15 55.2 0.4 1.3 1 0 0 1 1 1 1 CS domain zf-tcix PF14952.1 KFM13174.1 - 0.16 11.3 4.4 2.6 7.4 0.4 2.7 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding Ras PF00071.17 KFM13175.1 - 3.1e-56 189.2 0.0 3.7e-56 188.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM13175.1 - 2.4e-17 63.5 0.0 3.4e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM13175.1 - 6.5e-10 38.5 0.0 8.6e-10 38.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFM13175.1 - 0.0018 17.7 0.0 0.03 13.7 0.0 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFM13175.1 - 0.019 14.0 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF3799 PF12684.2 KFM13175.1 - 0.085 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 PDDEXK-like domain of unknown function (DUF3799) MMR_HSR1 PF01926.18 KFM13175.1 - 0.091 12.7 0.0 0.14 12.1 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF3591 PF12157.3 KFM13176.1 - 1e-156 521.9 0.0 1.4e-155 518.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) Bromodomain PF00439.20 KFM13176.1 - 1.1e-45 153.4 3.2 4.2e-23 81.0 0.5 3.0 2 0 0 2 2 2 2 Bromodomain TBP-binding PF09247.6 KFM13176.1 - 5.3e-24 84.1 3.4 1.7e-23 82.5 2.3 2.0 1 0 0 1 1 1 1 TATA box-binding protein binding zf-CCHC_6 PF15288.1 KFM13176.1 - 2.9e-15 55.6 0.3 7.9e-15 54.2 0.2 1.8 1 0 0 1 1 1 1 Zinc knuckle Glyco_transf_41 PF13844.1 KFM13177.1 - 5.7e-274 908.1 0.0 7.6e-274 907.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 41 TPR_1 PF00515.23 KFM13177.1 - 7.3e-98 316.5 28.4 2.2e-10 39.6 0.2 13.5 13 0 0 13 13 13 11 Tetratricopeptide repeat TPR_11 PF13414.1 KFM13177.1 - 8.1e-93 304.1 36.5 2.4e-16 59.1 0.4 8.8 7 2 2 9 9 9 8 TPR repeat TPR_17 PF13431.1 KFM13177.1 - 3.6e-75 242.0 28.3 3e-07 30.0 0.0 13.8 14 0 0 14 14 13 12 Tetratricopeptide repeat TPR_2 PF07719.12 KFM13177.1 - 1.7e-73 236.7 28.8 2.2e-08 33.3 0.3 13.2 13 0 0 13 13 12 11 Tetratricopeptide repeat TPR_12 PF13424.1 KFM13177.1 - 4.7e-65 215.4 39.7 5.1e-14 51.9 0.2 7.9 1 1 9 10 10 10 9 Tetratricopeptide repeat TPR_16 PF13432.1 KFM13177.1 - 2.2e-54 181.0 21.2 3.7e-10 40.1 0.3 8.5 3 2 6 10 10 10 9 Tetratricopeptide repeat TPR_14 PF13428.1 KFM13177.1 - 6.3e-54 175.5 17.0 1.3e-05 25.3 0.1 12.5 4 2 8 12 12 12 11 Tetratricopeptide repeat TPR_8 PF13181.1 KFM13177.1 - 1.9e-53 174.2 9.4 1.1e-05 24.8 0.1 12.3 12 0 0 12 12 11 11 Tetratricopeptide repeat TPR_7 PF13176.1 KFM13177.1 - 1.6e-45 149.3 18.4 2.4e-05 23.8 0.0 13.1 13 1 1 14 14 14 10 Tetratricopeptide repeat TPR_19 PF14559.1 KFM13177.1 - 1.3e-39 134.3 18.2 5.1e-06 26.7 0.4 9.5 3 3 5 9 9 9 8 Tetratricopeptide repeat TPR_10 PF13374.1 KFM13177.1 - 1.7e-26 91.3 43.0 1.5e-05 24.7 0.2 12.3 11 1 1 12 12 12 6 Tetratricopeptide repeat TPR_6 PF13174.1 KFM13177.1 - 8.2e-21 72.9 13.7 0.21 12.1 0.0 11.5 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_9 PF13371.1 KFM13177.1 - 9.8e-16 57.3 15.7 0.015 15.1 0.0 6.8 5 2 2 7 7 7 5 Tetratricopeptide repeat NARP1 PF12569.3 KFM13177.1 - 7.7e-15 54.6 6.1 0.0014 17.5 0.0 5.8 1 1 5 6 6 6 3 NMDA receptor-regulated protein 1 TPR_4 PF07721.9 KFM13177.1 - 4.7e-13 48.1 12.6 1.3 9.6 0.2 9.1 8 0 0 8 8 8 1 Tetratricopeptide repeat MIT PF04212.13 KFM13177.1 - 1.6e-09 37.4 21.0 0.027 14.3 0.0 9.0 7 2 3 10 10 9 3 MIT (microtubule interacting and transport) domain Apc3 PF12895.2 KFM13177.1 - 3.4e-08 33.5 22.8 0.0001 22.3 1.0 5.8 3 2 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 KFM13177.1 - 4.1e-08 32.6 8.6 0.00045 19.3 0.3 4.6 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_3 PF07720.7 KFM13177.1 - 3.5e-06 26.6 1.2 1.5 8.7 0.0 5.7 5 1 1 6 6 5 2 Tetratricopeptide repeat EST1_DNA_bind PF10373.4 KFM13177.1 - 2.6e-05 23.5 15.5 0.21 10.7 0.1 5.2 3 1 3 6 6 6 3 Est1 DNA/RNA binding domain FAT PF02259.18 KFM13177.1 - 0.00015 20.8 1.8 2 7.3 0.1 5.1 2 2 1 3 3 3 1 FAT domain TPR_21 PF09976.4 KFM13177.1 - 0.00016 21.6 12.3 0.42 10.5 0.0 5.5 4 2 2 6 6 5 3 Tetratricopeptide repeat SHNi-TPR PF10516.4 KFM13177.1 - 0.0066 15.6 3.3 26 4.1 0.0 5.4 7 0 0 7 7 7 0 SHNi-TPR RPN7 PF10602.4 KFM13177.1 - 0.0086 15.4 9.5 20 4.5 0.1 6.7 4 2 4 8 8 8 0 26S proteasome subunit RPN7 DUF3366 PF11846.3 KFM13177.1 - 0.0089 15.9 17.5 0.04 13.7 0.2 4.7 4 1 2 6 6 4 2 Domain of unknown function (DUF3366) TPR_5 PF12688.2 KFM13177.1 - 0.0098 15.9 5.6 1.2 9.1 0.2 4.2 3 2 2 5 5 4 2 Tetratrico peptide repeat Tcf25 PF04910.9 KFM13177.1 - 0.014 14.3 0.6 0.042 12.7 0.1 2.0 2 0 0 2 2 2 0 Transcriptional repressor TCF25 DUF627 PF04781.7 KFM13177.1 - 0.022 14.3 0.8 6.5 6.4 0.0 4.4 3 1 2 5 5 5 0 Protein of unknown function (DUF627) Mad3_BUB1_I PF08311.7 KFM13177.1 - 0.064 13.0 2.3 80 3.0 0.0 5.1 4 1 1 5 5 5 0 Mad3/BUB1 homology region 1 Fis1_TPR_C PF14853.1 KFM13177.1 - 0.069 13.0 0.6 0.99 9.3 0.0 3.3 3 0 0 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat TOM20_plant PF06552.7 KFM13177.1 - 0.084 12.4 0.4 28 4.2 0.0 3.6 3 2 0 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_20 PF14561.1 KFM13177.1 - 0.16 12.0 14.2 1.9 8.6 0.2 6.3 4 2 1 6 6 6 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 KFM13177.1 - 0.57 10.3 4.2 3.1 8.0 0.1 3.8 4 1 0 4 4 4 0 Alkyl sulfatase dimerisation BTAD PF03704.12 KFM13177.1 - 0.69 10.2 14.0 3.4 7.9 0.6 5.2 3 2 3 6 6 6 0 Bacterial transcriptional activator domain SprT-like PF10263.4 KFM13178.1 - 1.8e-07 30.9 0.0 3.5e-06 26.7 0.0 2.1 2 0 0 2 2 2 2 SprT-like family DUF775 PF05603.7 KFM13180.1 - 9.5e-41 139.5 0.5 1.2e-40 139.2 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF775) ANTH PF07651.11 KFM13180.1 - 0.056 12.1 0.0 0.081 11.6 0.0 1.1 1 0 0 1 1 1 0 ANTH domain GAT PF03127.9 KFM13181.1 - 2.7e-26 91.4 2.1 4.9e-26 90.6 1.5 1.4 1 0 0 1 1 1 1 GAT domain VHS PF00790.14 KFM13181.1 - 9.3e-18 64.2 0.2 1.7e-17 63.3 0.1 1.4 1 0 0 1 1 1 1 VHS domain DUF4611 PF15387.1 KFM13181.1 - 0.041 14.0 0.1 0.14 12.2 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) CtaG_Cox11 PF04442.9 KFM13182.1 - 1.1e-57 194.1 0.2 1.2e-57 193.9 0.2 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 PDZ PF00595.19 KFM13183.1 - 4.7e-11 42.7 0.4 1.8e-10 40.8 0.1 2.1 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) WW PF00397.21 KFM13183.1 - 9.1e-11 41.4 0.6 1.6e-10 40.6 0.4 1.4 1 0 0 1 1 1 1 WW domain TPR_MLP1_2 PF07926.7 KFM13183.1 - 0.0078 15.9 14.7 0.0078 15.9 10.2 2.4 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein PDZ_2 PF13180.1 KFM13183.1 - 0.01 15.6 0.1 0.04 13.8 0.0 2.0 2 0 0 2 2 2 0 PDZ domain TcdA_TcdB PF12919.2 KFM13183.1 - 0.21 10.0 5.8 0.37 9.2 4.0 1.3 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain DUF572 PF04502.8 KFM13183.1 - 2.3 7.3 17.1 0.081 12.1 7.6 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF1664 PF07889.7 KFM13183.1 - 4.8 7.0 11.7 1.9 8.3 3.8 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) bZIP_2 PF07716.10 KFM13184.1 - 2e-17 62.7 12.6 3.5e-17 61.9 8.8 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KFM13184.1 - 0.00022 21.1 10.0 0.00042 20.2 7.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor Shugoshin_N PF07558.6 KFM13184.1 - 0.012 15.3 0.4 0.02 14.5 0.3 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region bZIP_Maf PF03131.12 KFM13184.1 - 0.023 14.9 8.0 0.027 14.7 4.9 1.5 1 1 0 1 1 1 0 bZIP Maf transcription factor HALZ PF02183.13 KFM13184.1 - 0.057 13.1 0.5 0.12 12.0 0.3 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper FlaC_arch PF05377.6 KFM13184.1 - 0.062 13.2 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) HlyIII PF03006.15 KFM13185.1 - 7.6e-44 149.7 22.7 8.6e-44 149.5 15.7 1.0 1 0 0 1 1 1 1 Haemolysin-III related Meckelin PF09773.4 KFM13185.1 - 0.1 10.3 3.0 0.13 10.0 2.1 1.0 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) PIRT PF15099.1 KFM13186.1 - 7.6e-62 206.2 0.8 8.4e-62 206.1 0.5 1.0 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family Claudin_2 PF13903.1 KFM13186.1 - 0.00018 21.2 0.3 0.00019 21.1 0.2 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Neurensin PF14927.1 KFM13186.1 - 0.00046 19.5 2.4 0.12 11.7 0.0 2.1 1 1 1 2 2 2 2 Neurensin IncA PF04156.9 KFM13186.1 - 0.001 18.7 1.4 0.0013 18.3 1.0 1.1 1 0 0 1 1 1 1 IncA protein DUF4131 PF13567.1 KFM13186.1 - 0.0011 18.4 0.4 0.0014 18.0 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) NfeD PF01957.13 KFM13186.1 - 0.0022 18.1 0.3 0.0029 17.7 0.2 1.1 1 0 0 1 1 1 1 NfeD-like C-terminal, partner-binding UPF0542 PF15086.1 KFM13186.1 - 0.012 15.2 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 DUF373 PF04123.8 KFM13186.1 - 0.06 12.3 0.2 0.068 12.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF3040 PF11239.3 KFM13186.1 - 0.075 13.0 1.8 0.13 12.3 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) START PF01852.14 KFM13187.1 - 6.8e-31 107.2 0.0 7.8e-31 106.9 0.0 1.0 1 0 0 1 1 1 1 START domain DUF3074 PF11274.3 KFM13187.1 - 0.0074 15.9 0.1 0.025 14.2 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3074) fn3 PF00041.16 KFM13188.1 - 9.4e-13 48.1 0.1 2.1e-12 46.9 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III domain Ank_4 PF13637.1 KFM13188.1 - 2.6e-07 30.9 0.0 8.5e-07 29.3 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KFM13188.1 - 4.4e-06 26.9 0.0 2.2e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFM13188.1 - 7e-06 26.1 0.1 0.0021 18.2 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 KFM13188.1 - 0.0013 18.4 0.2 0.041 13.7 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat SulA PF03846.9 KFM13189.1 - 0.029 14.0 0.7 0.45 10.2 0.1 2.8 3 0 0 3 3 3 0 Cell division inhibitor SulA Noggin PF05806.7 KFM13190.1 - 1.2e-103 345.1 0.4 1.3e-103 345.0 0.3 1.0 1 0 0 1 1 1 1 Noggin Lentiviral_Tat PF02998.9 KFM13190.1 - 8.9 6.2 8.2 6 6.7 0.3 2.2 1 1 0 2 2 2 0 Lentiviral Tat protein DUF4543 PF15076.1 KFM13191.1 - 9.1e-48 160.1 1.6 1e-47 159.9 1.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4543) DAGK_acc PF00609.14 KFM13192.1 - 7.1e-50 169.2 0.0 1.2e-49 168.5 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 KFM13192.1 - 2.4e-26 91.6 0.0 3.5e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.17 KFM13192.1 - 2.3e-13 49.6 40.0 2.5e-08 33.5 14.8 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Laminin_G_2 PF02210.19 KFM13192.1 - 0.08 12.9 0.0 0.29 11.1 0.0 1.8 2 0 0 2 2 2 0 Laminin G domain NTR PF01759.16 KFM13193.1 - 5.6e-06 25.8 0.0 9.7e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 UNC-6/NTR/C345C module TIMP PF00965.12 KFM13193.1 - 0.0015 18.1 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase SPRY PF00622.23 KFM13194.1 - 3.5e-16 59.4 0.5 7.2e-16 58.4 0.3 1.5 1 0 0 1 1 1 1 SPRY domain PRY PF13765.1 KFM13194.1 - 5.6e-15 54.5 1.0 4.9e-14 51.5 0.0 2.9 3 0 0 3 3 3 1 SPRY-associated domain zf-B_box PF00643.19 KFM13194.1 - 0.0003 20.6 11.9 0.0003 20.6 8.3 2.7 3 0 0 3 3 3 1 B-box zinc finger Peptidase_S10 PF00450.17 KFM13196.1 - 2e-83 280.8 0.5 2.2e-83 280.7 0.3 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase UPF0114 PF03350.11 KFM13196.1 - 0.13 12.1 0.0 0.47 10.3 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein family, UPF0114 RBD-FIP PF09457.5 KFM13197.1 - 5.7e-13 48.4 2.9 5.7e-13 48.4 2.0 5.0 6 1 1 7 7 7 1 FIP domain bZIP_1 PF00170.16 KFM13197.1 - 0.00076 19.3 6.6 0.00076 19.3 4.6 6.4 3 1 2 6 6 6 2 bZIP transcription factor bZIP_2 PF07716.10 KFM13197.1 - 0.0037 17.0 4.4 0.0037 17.0 3.1 6.1 6 1 0 6 6 6 2 Basic region leucine zipper DUF904 PF06005.7 KFM13197.1 - 0.0091 16.2 7.4 0.0091 16.2 5.1 5.8 3 2 3 6 6 6 3 Protein of unknown function (DUF904) EF-hand_8 PF13833.1 KFM13197.1 - 0.052 13.1 0.2 0.26 10.9 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair HALZ PF02183.13 KFM13197.1 - 0.28 10.9 23.0 0.12 12.1 1.0 4.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper Shugoshin_N PF07558.6 KFM13197.1 - 1.6 8.4 16.9 2.2 8.0 0.7 4.7 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region MbeD_MobD PF04899.7 KFM13197.1 - 1.6 8.6 13.1 0.79 9.6 1.6 4.4 3 1 2 5 5 5 0 MbeD/MobD like HAP1_N PF04849.8 KFM13197.1 - 2.7 6.8 47.3 0.048 12.6 17.6 3.1 1 1 1 2 2 2 0 HAP1 N-terminal conserved region FlaC_arch PF05377.6 KFM13197.1 - 3.9 7.4 20.4 1.9 8.4 1.3 4.9 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) U3_assoc_6 PF08640.6 KFM13198.1 - 1.7e-16 59.7 4.5 1.7e-16 59.7 3.1 3.3 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 KFM13198.1 - 0.00016 22.0 1.9 1.2 9.9 0.0 5.5 5 1 1 6 6 6 1 Tetratricopeptide repeat VEFS-Box PF09733.4 KFM13199.1 - 4.2e-56 188.5 3.1 8.6e-56 187.5 2.1 1.6 1 0 0 1 1 1 1 VEFS-Box of polycomb protein zf-H2C2_5 PF13909.1 KFM13199.1 - 1.4 9.2 5.1 5.6 7.3 3.6 2.1 1 0 0 1 1 1 0 C2H2-type zinc-finger domain fn3 PF00041.16 KFM13200.1 - 0.0064 16.5 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain AAA PF00004.24 KFM13201.1 - 8.7e-07 29.2 5.2 2.2e-06 27.8 0.0 3.4 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFM13201.1 - 0.00035 20.7 0.3 0.0018 18.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KFM13201.1 - 0.0007 20.4 2.4 0.0016 19.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KFM13201.1 - 0.00084 19.3 0.0 0.0061 16.5 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 KFM13201.1 - 0.0067 16.1 0.0 0.02 14.6 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 KFM13201.1 - 0.015 14.3 0.0 0.054 12.5 0.0 1.9 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus ArfGap PF01412.13 KFM13202.1 - 5.3e-30 103.6 0.2 1e-29 102.6 0.2 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.24 KFM13202.1 - 4e-15 55.8 0.6 2e-06 27.9 0.0 3.0 2 1 0 2 2 2 2 PH domain PH_11 PF15413.1 KFM13202.1 - 1.6e-12 47.6 3.9 2.1e-05 24.7 0.1 3.5 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 KFM13202.1 - 1.7e-08 34.3 3.7 0.00035 20.5 0.0 3.3 2 2 0 2 2 2 2 Pleckstrin homology domain Mcp5_PH PF12814.2 KFM13202.1 - 4.5e-05 23.3 0.2 0.00035 20.4 0.0 2.2 2 1 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology EF_assoc_2 PF08356.7 KFM13203.1 - 6.6e-35 118.7 0.0 2.2e-34 117.0 0.0 1.9 2 0 0 2 2 2 1 EF hand associated Miro PF08477.8 KFM13203.1 - 6.1e-32 110.6 0.0 6.2e-15 55.7 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein EF_assoc_1 PF08355.7 KFM13203.1 - 6.6e-31 105.4 2.2 8.6e-31 105.0 0.3 2.0 2 0 0 2 2 2 1 EF hand associated Ras PF00071.17 KFM13203.1 - 3.4e-23 81.8 0.1 2.8e-15 56.0 0.0 2.7 2 1 0 2 2 2 2 Ras family EF-hand_6 PF13405.1 KFM13203.1 - 4.4e-07 29.2 1.0 0.0035 17.0 0.0 3.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 KFM13203.1 - 1.1e-06 27.4 2.4 0.023 13.9 0.1 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 KFM13203.1 - 5.7e-06 26.3 0.2 0.21 11.7 0.0 3.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KFM13203.1 - 0.00091 18.8 1.3 0.23 11.1 0.1 2.9 2 0 0 2 2 2 1 EF-hand domain pair MMR_HSR1 PF01926.18 KFM13203.1 - 0.0026 17.7 0.0 1.2 9.1 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KFM13203.1 - 0.0087 15.8 0.0 0.6 9.9 0.0 2.5 2 0 0 2 2 2 1 Dynamin family EF-hand_5 PF13202.1 KFM13203.1 - 0.018 14.3 2.7 3.2 7.2 0.3 2.6 2 0 0 2 2 2 0 EF hand Rad4 PF03835.10 KFM13203.1 - 0.022 14.1 0.0 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 Rad4 transglutaminase-like domain AAA_14 PF13173.1 KFM13203.1 - 0.06 13.2 0.0 3.1 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KFM13203.1 - 0.09 13.0 0.0 0.47 10.7 0.0 2.1 2 0 0 2 2 2 0 ABC transporter PduV-EutP PF10662.4 KFM13203.1 - 0.11 12.0 0.1 2.5 7.6 0.0 2.7 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation EF-hand_4 PF12763.2 KFM13203.1 - 0.24 11.1 1.4 2.3 8.0 0.0 3.0 3 0 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand Rhomboid PF01694.17 KFM13204.1 - 1.5e-33 115.8 10.8 1.5e-33 115.8 7.5 2.1 2 0 0 2 2 2 1 Rhomboid family EF-hand_7 PF13499.1 KFM13204.1 - 8.4e-08 32.2 0.0 1.4e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 KFM13204.1 - 7.2e-07 28.7 0.0 8.4e-05 22.1 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KFM13204.1 - 9.5e-07 27.6 0.0 0.016 14.4 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KFM13204.1 - 0.0031 17.2 0.0 0.046 13.6 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_9 PF14658.1 KFM13204.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain Njmu-R1 PF15053.1 KFM13205.1 - 3.3e-208 690.4 0.3 3.7e-208 690.3 0.2 1.0 1 0 0 1 1 1 1 Mjmu-R1-like protein family DUF3449 PF11931.3 KFM13206.1 - 0.29 10.6 3.8 2.7 7.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) zf-FCS PF06467.9 KFM13206.1 - 2 8.1 6.0 0.26 10.9 1.1 1.8 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif TPR_19 PF14559.1 KFM13207.1 - 0.00093 19.4 0.9 0.0039 17.5 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat RNA_pol_Rpb2_2 PF04561.9 KFM13207.1 - 0.0034 16.8 0.4 0.014 14.8 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 Pkinase PF00069.20 KFM13208.1 - 4.2e-46 157.1 0.0 6.4e-46 156.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 KFM13208.1 - 6.6e-45 152.1 0.3 1.1e-44 151.3 0.2 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 KFM13208.1 - 5e-26 91.3 0.0 7.7e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PQQ_2 PF13360.1 KFM13208.1 - 1.5e-07 31.1 0.0 0.012 15.1 0.0 2.6 1 1 0 2 2 2 2 PQQ-like domain APH PF01636.18 KFM13208.1 - 2.7e-05 24.0 0.2 0.09 12.4 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family PQQ PF01011.16 KFM13208.1 - 3.3e-05 23.2 0.3 0.032 13.7 0.0 3.6 5 0 0 5 5 5 2 PQQ enzyme repeat Kdo PF06293.9 KFM13208.1 - 0.0035 16.4 0.0 0.0068 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KFM13208.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL PQQ_3 PF13570.1 KFM13208.1 - 0.34 11.2 1.5 5.6 7.3 0.0 3.7 4 1 0 4 4 4 0 PQQ-like domain DUF2404 PF10296.4 KFM13209.1 - 4.8e-27 93.9 1.6 4.1e-26 90.9 0.0 2.7 3 0 0 3 3 3 1 Putative integral membrane protein conserved region (DUF2404) Tombus_P33 PF08500.5 KFM13209.1 - 0.083 12.6 0.0 0.26 11.0 0.0 1.9 1 0 0 1 1 1 0 Tombusvirus p33 Ig_2 PF13895.1 KFM13210.1 - 1.1e-42 143.9 3.2 7.2e-08 32.4 0.0 6.2 6 0 0 6 6 6 6 Immunoglobulin domain Ig_3 PF13927.1 KFM13210.1 - 3.7e-17 62.5 2.3 0.046 14.2 0.0 7.0 7 0 0 7 7 7 5 Immunoglobulin domain I-set PF07679.11 KFM13210.1 - 1.1e-14 54.0 13.1 0.014 15.2 0.1 7.5 6 3 0 6 6 6 5 Immunoglobulin I-set domain V-set PF07686.12 KFM13210.1 - 2.6e-13 49.8 7.1 0.023 14.5 0.2 7.4 6 2 0 6 6 6 4 Immunoglobulin V-set domain ig PF00047.20 KFM13210.1 - 2.2e-07 30.9 4.8 0.19 11.8 0.0 6.8 6 1 0 6 6 6 1 Immunoglobulin domain C2-set PF05790.10 KFM13210.1 - 0.0027 17.6 1.2 8.6 6.4 0.0 5.1 4 0 0 4 4 4 1 Immunoglobulin C2-set domain Ig_2 PF13895.1 KFM13211.1 - 1.1e-19 70.3 0.9 6.8e-09 35.7 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 KFM13211.1 - 1.3e-11 44.8 0.3 4.8e-05 23.7 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 KFM13211.1 - 2.7e-07 30.3 0.0 0.022 14.6 0.0 2.4 2 1 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.20 KFM13211.1 - 3.8e-07 30.1 0.1 0.013 15.6 0.0 2.9 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.12 KFM13211.1 - 8.9e-07 28.8 6.0 0.11 12.3 0.2 4.0 2 2 0 2 2 2 2 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFM13211.1 - 0.005 16.7 0.0 0.6 10.0 0.0 2.2 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain HGTP_anticodon PF03129.15 KFM13212.1 - 3.8e-11 42.7 0.0 6.2e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.20 KFM13212.1 - 0.026 14.1 0.0 0.12 12.0 0.0 2.0 2 1 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) DEAD PF00270.24 KFM13213.1 - 1.8e-42 144.7 0.0 1.4e-41 141.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase P68HR PF08061.6 KFM13213.1 - 4.5e-27 93.4 20.0 6.2e-14 51.4 3.2 2.6 2 0 0 2 2 2 2 P68HR (NUC004) repeat Helicase_C PF00271.26 KFM13213.1 - 1.7e-26 91.8 0.0 8.8e-26 89.5 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFM13213.1 - 0.00045 20.1 0.0 0.019 14.7 0.0 2.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 KFM13213.1 - 0.0073 16.2 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain HECT PF00632.20 KFM13214.1 - 6.9e-101 337.5 0.0 9.9e-101 337.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 KFM13214.1 - 2.8e-29 100.6 10.9 1.3e-10 40.9 0.2 3.6 3 0 0 3 3 3 3 WW domain C2 PF00168.25 KFM13214.1 - 1.1e-14 54.0 0.1 2.1e-14 53.1 0.1 1.5 1 0 0 1 1 1 1 C2 domain Arm PF00514.18 KFM13215.1 - 1.9e-78 255.9 9.9 8e-12 44.5 0.0 8.8 10 0 0 10 10 10 8 Armadillo/beta-catenin-like repeat IBB PF01749.15 KFM13215.1 - 5.1e-26 90.6 7.1 1.2e-25 89.4 4.9 1.6 1 0 0 1 1 1 1 Importin beta binding domain HEAT_2 PF13646.1 KFM13215.1 - 2.6e-15 56.4 0.1 0.00073 19.7 0.0 5.8 1 1 4 6 6 6 3 HEAT repeats HEAT_EZ PF13513.1 KFM13215.1 - 3.5e-15 55.9 0.2 0.00015 22.1 0.0 5.6 3 1 3 6 6 6 4 HEAT-like repeat HEAT PF02985.17 KFM13215.1 - 4.1e-07 29.5 3.7 0.043 13.9 0.0 5.7 9 0 0 9 9 9 2 HEAT repeat KAP PF05804.7 KFM13215.1 - 0.00025 19.1 0.1 0.085 10.7 0.0 2.8 2 1 1 3 3 3 2 Kinesin-associated protein (KAP) V-ATPase_H_C PF11698.3 KFM13215.1 - 0.016 15.1 1.3 11 5.9 0.1 3.6 4 1 0 4 4 4 0 V-ATPase subunit H NTR PF01759.16 KFM13217.1 - 0.062 12.8 0.1 0.1 12.1 0.1 1.6 1 1 0 1 1 1 0 UNC-6/NTR/C345C module Bromodomain PF00439.20 KFM13218.1 - 1.9e-26 91.7 1.3 8.1e-26 89.7 0.1 2.4 2 0 0 2 2 2 1 Bromodomain DDT PF02791.12 KFM13218.1 - 9.2e-22 76.5 0.3 1.9e-21 75.6 0.2 1.6 1 0 0 1 1 1 1 DDT domain PHD PF00628.24 KFM13218.1 - 4e-18 64.8 28.8 1.4e-09 37.4 5.0 3.0 2 0 0 2 2 2 2 PHD-finger WHIM1 PF15612.1 KFM13218.1 - 4.3e-06 26.3 0.0 1.3e-05 24.9 0.0 1.9 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM2 PF15613.1 KFM13218.1 - 0.0018 18.1 1.7 0.003 17.4 0.2 2.1 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 2 C1_1 PF00130.17 KFM13218.1 - 0.57 9.9 14.3 3 7.6 0.9 2.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 KFM13218.1 - 1.4 8.3 18.1 0.81 9.0 4.2 2.7 2 0 0 2 2 2 0 PHD-finger NUC205 PF08168.6 KFM13219.1 - 0.034 13.5 0.0 0.094 12.1 0.0 1.8 1 0 0 1 1 1 0 NUC205 domain IP_trans PF02121.13 KFM13220.1 - 7.1e-71 238.3 5.2 8.4e-71 238.1 3.6 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Claudin_2 PF13903.1 KFM13221.1 - 3e-30 105.1 1.6 5.2e-30 104.3 1.1 1.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 KFM13221.1 - 3.6e-15 56.0 7.3 1.7e-08 34.3 3.4 2.1 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family DUF805 PF05656.9 KFM13221.1 - 0.00013 21.7 0.8 0.00013 21.7 0.5 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF805) DUF981 PF06168.6 KFM13221.1 - 0.011 15.5 1.7 0.033 13.9 0.7 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF981) Claudin_3 PF06653.6 KFM13221.1 - 0.024 14.3 6.2 0.23 11.1 2.5 2.1 2 0 0 2 2 2 0 Tight junction protein, Claudin-like DUF1049 PF06305.6 KFM13221.1 - 0.064 12.7 0.1 0.064 12.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF3040 PF11239.3 KFM13221.1 - 0.45 10.5 3.3 8.2 6.5 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3040) DUF2721 PF11026.3 KFM13221.1 - 1.3 8.6 9.2 0.25 10.9 1.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) zf-LITAF-like PF10601.4 KFM13221.1 - 2.5 8.0 8.0 2.3 8.1 0.0 2.7 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain PMP22_Claudin PF00822.15 KFM13222.1 - 1.2e-24 86.7 0.0 2.2e-24 85.9 0.0 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFM13222.1 - 1.7e-11 44.1 0.0 2.6e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction AA_permease_2 PF13520.1 KFM13222.1 - 0.0015 17.1 0.1 0.002 16.7 0.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2269 PF10027.4 KFM13222.1 - 0.0049 16.6 0.0 0.0078 15.9 0.0 1.2 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2269) Polysacc_synt_3 PF13440.1 KFM13222.1 - 0.018 14.5 0.1 0.044 13.2 0.1 1.7 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein TMEM173 PF15009.1 KFM13222.1 - 0.034 12.9 0.0 0.051 12.3 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 173 DUF4225 PF13988.1 KFM13222.1 - 0.04 13.3 0.1 0.061 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4225) DuoxA PF10204.4 KFM13222.1 - 0.098 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Dual oxidase maturation factor PMP22_Claudin PF00822.15 KFM13223.1 - 3.7e-22 78.7 4.2 8.9e-22 77.4 2.9 1.6 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFM13223.1 - 5.6e-19 68.4 3.3 7.7e-19 68.0 2.3 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Tetraspannin PF00335.15 KFM13223.1 - 5.8e-05 22.4 2.4 0.00011 21.5 1.5 1.6 1 1 0 1 1 1 1 Tetraspanin family DUF716 PF04819.7 KFM13223.1 - 0.043 13.2 0.5 0.083 12.3 0.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF716) SUR7 PF06687.7 KFM13223.1 - 0.63 9.5 12.5 1.6 8.2 7.6 2.3 1 1 1 2 2 2 0 SUR7/PalI family Claudin_3 PF06653.6 KFM13223.1 - 1.3 8.7 10.1 3 7.5 7.0 1.6 1 1 0 1 1 1 0 Tight junction protein, Claudin-like MFS_1 PF07690.11 KFM13223.1 - 2 7.0 14.4 15 4.1 10.4 1.8 1 1 0 1 1 1 0 Major Facilitator Superfamily Pkinase_C PF00433.19 KFM13224.1 - 1.1e-09 38.6 0.4 1.3e-09 38.4 0.3 1.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Ribosomal_L10 PF00466.15 KFM13225.1 - 4.8e-07 29.6 0.1 7.1e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 IF-2B PF01008.12 KFM13225.1 - 0.11 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Initiation factor 2 subunit family LRR_4 PF12799.2 KFM13226.1 - 7.1e-13 47.8 5.3 4.2e-09 35.8 0.8 2.2 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 KFM13226.1 - 3.6e-06 26.3 2.8 0.052 13.7 0.1 3.0 3 0 0 3 3 3 2 Leucine rich repeat LRR_8 PF13855.1 KFM13226.1 - 3.8e-06 26.5 2.2 5.7e-06 26.0 0.7 1.9 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.28 KFM13226.1 - 2e-05 23.9 2.6 0.034 14.1 0.1 2.9 2 0 0 2 2 2 2 Leucine Rich Repeat LRR_6 PF13516.1 KFM13226.1 - 0.0013 18.5 1.2 0.32 11.2 0.2 2.8 2 0 0 2 2 2 2 Leucine Rich repeat LRR_3 PF07725.7 KFM13226.1 - 0.13 12.0 2.1 2.6 7.9 0.1 3.2 3 0 0 3 3 3 0 Leucine Rich Repeat Peptidase_C69 PF03577.10 KFM13227.1 - 4.3e-08 32.4 0.0 8.1e-08 31.5 0.0 1.4 1 1 0 1 1 1 1 Peptidase family C69 zf-C2H2 PF00096.21 KFM13228.1 - 7.1e-08 32.3 8.0 1.2e-05 25.3 0.4 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFM13228.1 - 7.2e-07 29.2 0.2 7.2e-07 29.2 0.1 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFM13228.1 - 3.4e-06 26.9 9.1 0.00064 19.8 0.7 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM13228.1 - 0.096 12.8 0.0 23 5.2 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFM13228.1 - 9.3 6.3 7.4 3.9 7.5 0.0 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger DUF773 PF05600.7 KFM13229.1 - 5.1e-45 154.2 0.1 5.5e-45 154.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF773) DUF3849 PF12960.2 KFM13229.1 - 0.049 13.5 0.0 0.059 13.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3849) TPR_19 PF14559.1 KFM13229.1 - 0.086 13.1 0.6 0.33 11.3 0.1 2.0 2 1 0 2 2 2 0 Tetratricopeptide repeat UPF0175 PF03683.8 KFM13229.1 - 0.17 11.3 0.5 2.8 7.4 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0175) Chromo_shadow PF01393.14 KFM13230.1 - 4.5e-39 132.0 0.1 3.8e-34 116.3 0.0 2.2 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.19 KFM13230.1 - 4.6e-24 83.8 3.9 4.6e-19 67.8 0.4 2.9 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.1 KFM13230.1 - 0.0022 17.8 0.1 0.0056 16.5 0.2 1.6 2 0 0 2 2 2 1 Polycomb-like MTF2 factor 2 DUF2201_N PF13203.1 KFM13230.1 - 0.38 9.8 2.3 0.44 9.6 1.6 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain PX PF00787.19 KFM13231.1 - 6e-26 90.4 0.5 7.3e-26 90.1 0.4 1.1 1 0 0 1 1 1 1 PX domain PH PF00169.24 KFM13232.1 - 3e-10 40.2 0.7 3.5e-10 40.0 0.5 1.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KFM13232.1 - 8.5e-05 22.7 0.9 0.0001 22.5 0.6 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 KFM13232.1 - 0.021 14.6 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 PH domain Homeobox PF00046.24 KFM13233.1 - 1e-22 79.4 7.2 1.4e-22 79.0 5.0 1.2 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFM13233.1 - 0.19 11.4 1.7 0.32 10.7 0.2 2.0 2 0 0 2 2 2 0 Homeobox KN domain DUF4074 PF13293.1 KFM13234.1 - 8.9e-35 118.7 9.9 8.9e-35 118.7 6.9 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4074) Homeobox PF00046.24 KFM13234.1 - 2.2e-21 75.1 4.6 2.2e-21 75.1 3.2 1.7 2 0 0 2 2 2 1 Homeobox domain Homeobox PF00046.24 KFM13236.1 - 2e-22 78.5 8.1 3.9e-22 77.6 5.6 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFM13236.1 - 0.054 13.2 1.0 0.054 13.2 0.7 2.1 2 0 0 2 2 2 0 Homeobox KN domain Menin PF05053.8 KFM13236.1 - 2.3 6.2 6.2 3.1 5.8 4.3 1.1 1 0 0 1 1 1 0 Menin Homeobox PF00046.24 KFM13237.1 - 3.1e-22 77.9 7.8 4.5e-22 77.4 5.4 1.3 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFM13237.1 - 0.016 14.9 0.8 0.026 14.2 0.5 1.3 1 0 0 1 1 1 0 Homeobox KN domain Homeobox PF00046.24 KFM13238.1 - 2e-21 75.3 2.2 3.9e-21 74.4 1.5 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFM13238.1 - 0.016 14.9 0.0 0.039 13.6 0.0 1.7 1 0 0 1 1 1 0 Homeobox KN domain Hox9_act PF04617.8 KFM13239.1 - 3.4e-56 190.3 2.6 4.8e-56 189.8 1.8 1.2 1 0 0 1 1 1 1 Hox9 activation region Homeobox PF00046.24 KFM13239.1 - 1.7e-18 65.9 7.0 2.8e-18 65.2 4.8 1.4 1 0 0 1 1 1 1 Homeobox domain HTH_23 PF13384.1 KFM13239.1 - 0.012 15.2 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain CALCOCO1 PF07888.6 KFM13240.1 - 3.2e-25 88.4 54.5 8e-23 80.5 37.7 2.9 1 1 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like TBPIP PF07106.8 KFM13240.1 - 0.007 15.9 15.0 0.007 15.9 10.4 3.2 1 1 2 3 3 3 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4164 PF13747.1 KFM13240.1 - 0.013 15.5 3.3 0.013 15.5 2.3 4.1 2 1 2 4 4 4 0 Domain of unknown function (DUF4164) DUF4201 PF13870.1 KFM13240.1 - 0.014 14.8 6.4 0.014 14.8 4.4 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) zf-H2C2_2 PF13465.1 KFM13240.1 - 0.018 15.3 1.1 2.1 8.8 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_6 PF13912.1 KFM13240.1 - 0.055 13.3 0.2 16 5.5 0.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger GAS PF13851.1 KFM13240.1 - 0.097 11.8 58.3 0.045 12.9 14.4 3.4 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding zf-C2H2_4 PF13894.1 KFM13240.1 - 0.19 12.1 4.6 2.9 8.4 0.0 3.2 2 1 1 3 3 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KFM13240.1 - 0.26 11.0 3.2 1.4 8.6 0.0 2.9 3 0 0 3 3 3 0 zinc-finger of a C2HC-type WEMBL PF05701.6 KFM13240.1 - 0.59 8.5 44.1 0.0067 14.9 22.2 2.0 1 1 1 2 2 2 0 Weak chloroplast movement under blue light DUF883 PF05957.8 KFM13240.1 - 0.97 9.8 0.0 0.97 9.8 0.0 3.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Reo_sigmaC PF04582.7 KFM13240.1 - 1.9 7.5 11.2 1 8.4 4.6 2.1 1 1 2 3 3 3 0 Reovirus sigma C capsid protein ATP-synt_C PF00137.16 KFM13241.1 - 0.0094 15.8 10.4 0.016 15.1 7.2 1.4 1 0 0 1 1 1 1 ATP synthase subunit C UQ_con PF00179.21 KFM13242.1 - 1.7e-30 105.3 0.1 3.1e-30 104.4 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 KFM13242.1 - 0.00023 20.8 2.7 0.00062 19.4 0.0 2.5 3 0 0 3 3 3 1 UEV domain RWD PF05773.17 KFM13242.1 - 0.028 14.3 0.8 0.035 14.0 0.0 1.6 2 0 0 2 2 2 0 RWD domain Prok-E2_B PF14461.1 KFM13242.1 - 0.036 13.8 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B EAP30 PF04157.11 KFM13243.1 - 4.2e-67 225.5 0.1 4.8e-67 225.3 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Apolipoprotein PF01442.13 KFM13243.1 - 0.059 12.8 4.4 0.073 12.5 0.2 2.4 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain DUF1342 PF07072.6 KFM13243.1 - 0.23 11.0 2.3 13 5.3 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1342) L27_2 PF09045.5 KFM13243.1 - 0.33 10.5 3.4 0.38 10.3 0.0 2.6 3 0 0 3 3 3 0 L27_2 Hormone_2 PF00123.15 KFM13244.1 - 6.2e-12 45.1 4.7 1.4e-08 34.4 0.2 3.2 3 0 0 3 3 3 3 Peptide hormone KH_1 PF00013.24 KFM13245.1 - 4e-55 183.3 12.4 1.7e-13 50.0 0.2 4.5 4 0 0 4 4 4 4 KH domain KH_3 PF13014.1 KFM13245.1 - 3.1e-36 122.4 12.2 1.2e-08 34.4 0.1 4.7 4 0 0 4 4 4 4 KH domain KH_2 PF07650.12 KFM13245.1 - 2e-19 68.9 2.2 0.00049 19.6 0.0 4.6 4 0 0 4 4 4 4 KH domain KH_4 PF13083.1 KFM13245.1 - 1.5e-15 56.5 1.2 0.0016 18.0 0.0 5.0 5 0 0 5 5 5 4 KH domain KH_5 PF13184.1 KFM13245.1 - 3.1e-09 36.5 2.8 0.11 12.3 0.0 4.4 4 0 0 4 4 4 3 NusA-like KH domain RRM_1 PF00076.17 KFM13245.1 - 1.6e-08 34.0 0.0 3.5e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM13245.1 - 7e-06 25.7 0.0 1.9e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM13245.1 - 4e-05 23.5 0.0 8.8e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) dUTPase PF00692.14 KFM13245.1 - 0.064 12.7 0.1 23 4.4 0.0 3.1 4 0 0 4 4 4 0 dUTPase YtzH PF14165.1 KFM13245.1 - 0.11 12.7 3.8 0.85 9.8 0.2 3.2 3 1 1 4 4 4 0 YtzH-like protein G-gamma PF00631.17 KFM13246.1 - 2e-13 49.8 0.1 2.2e-13 49.7 0.1 1.0 1 0 0 1 1 1 1 GGL domain TPD52 PF04201.10 KFM13246.1 - 0.012 15.2 1.8 0.014 15.1 1.2 1.1 1 0 0 1 1 1 0 Tumour protein D52 family Herpes_UL25 PF01499.11 KFM13246.1 - 0.023 13.0 0.2 0.023 13.0 0.1 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF3294 PF07957.6 KFM13246.1 - 0.14 11.6 2.3 0.17 11.3 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) Cwf_Cwc_15 PF04889.7 KFM13246.1 - 0.2 11.3 3.2 0.21 11.2 2.2 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Abi_HHR PF07815.9 KFM13247.1 - 8.2e-26 89.9 0.0 1.4e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Abl-interactor HHR SH3_9 PF14604.1 KFM13247.1 - 5.5e-14 51.4 0.1 1.6e-13 49.9 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 KFM13247.1 - 5.2e-10 38.5 0.0 8e-10 37.9 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFM13247.1 - 1.5e-06 27.5 0.0 3.1e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 Variant SH3 domain Put_Phosphatase PF06888.7 KFM13248.1 - 2.3e-100 334.6 0.0 2.5e-100 334.4 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.2 KFM13248.1 - 4.6e-08 33.4 0.0 6.8e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KFM13248.1 - 3e-05 24.3 0.1 0.00013 22.2 0.0 2.0 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase PNK3P PF08645.6 KFM13248.1 - 0.0085 15.5 0.2 1.4 8.3 0.0 2.5 2 1 0 2 2 2 2 Polynucleotide kinase 3 phosphatase Hydrolase PF00702.21 KFM13248.1 - 0.055 13.8 0.0 0.43 10.9 0.0 2.1 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase zf-H2C2_2 PF13465.1 KFM13249.1 - 3.1e-33 112.4 63.3 9.7e-09 35.1 1.0 9.6 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.21 KFM13249.1 - 5.5e-33 111.3 62.5 1.3e-05 25.2 1.0 9.4 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM13249.1 - 2e-21 74.6 49.6 7.3e-05 22.8 0.5 9.0 9 0 0 9 9 9 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM13249.1 - 2.9e-11 43.1 37.9 0.02 15.0 0.0 8.1 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM13249.1 - 9.4e-11 41.5 38.5 0.0019 18.3 0.1 8.0 8 0 0 8 8 7 4 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 KFM13249.1 - 0.00097 18.7 39.1 1.2 8.8 0.0 7.9 8 0 0 8 8 8 4 zinc-finger of a C2HC-type ADK_lid PF05191.9 KFM13249.1 - 0.0022 17.6 16.3 0.035 13.7 0.3 5.1 5 0 0 5 5 5 2 Adenylate kinase, active site lid zf-C2H2_6 PF13912.1 KFM13249.1 - 0.013 15.3 0.2 0.013 15.3 0.1 8.6 8 1 1 9 9 9 0 C2H2-type zinc finger zf-Di19 PF05605.7 KFM13249.1 - 0.028 14.5 1.2 0.028 14.5 0.9 5.1 4 2 0 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 KFM13249.1 - 0.061 13.4 47.3 0.53 10.4 1.4 6.2 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) BolA PF01722.13 KFM13249.1 - 0.11 12.4 4.7 7.1 6.6 0.0 3.5 3 1 0 3 3 3 0 BolA-like protein zf-FCS PF06467.9 KFM13249.1 - 0.16 11.6 28.9 0.038 13.6 1.0 6.2 5 1 2 7 7 7 0 MYM-type Zinc finger with FCS sequence motif LMBR1 PF04791.11 KFM13249.1 - 4.7 5.6 5.9 5.7 5.3 4.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein zf-CHY PF05495.7 KFM13249.1 - 4.9 7.3 45.0 0.1 12.7 2.9 5.2 1 1 4 5 5 5 0 CHY zinc finger RRN7 PF11781.3 KFM13249.1 - 8.6 5.9 20.3 1.4 8.4 0.1 6.3 7 0 0 7 7 7 0 RNA polymerase I-specific transcription initiation factor Rrn7 Band_7 PF01145.20 KFM13250.1 - 2.7e-26 92.5 1.0 3.6e-26 92.1 0.7 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.3 KFM13250.1 - 0.021 14.8 0.4 0.034 14.1 0.3 1.4 1 0 0 1 1 1 0 Mediator complex subunit 2 TNFR_c6 PF00020.13 KFM13251.1 - 6.3e-25 86.9 51.6 4e-10 39.5 3.6 5.0 5 0 0 5 5 5 4 TNFR/NGFR cysteine-rich region GCC2_GCC3 PF07699.8 KFM13251.1 - 0.022 14.3 10.0 0.022 14.3 6.9 5.6 4 1 1 5 5 5 0 GCC2 and GCC3 Neurexophilin PF06312.7 KFM13252.1 - 9.5e-100 332.3 2.1 1e-99 332.1 1.5 1.0 1 0 0 1 1 1 1 Neurexophilin Filamin PF00630.14 KFM13252.1 - 0.0076 16.8 0.5 0.56 10.7 0.0 2.2 1 1 0 2 2 2 1 Filamin/ABP280 repeat NigD PF12667.2 KFM13252.1 - 0.023 14.5 0.0 0.031 14.0 0.0 1.1 1 0 0 1 1 1 0 NigD-like protein CHORD PF04968.7 KFM13252.1 - 2.8 8.2 8.1 0.22 11.7 2.4 1.7 2 0 0 2 2 2 0 CHORD BTB PF00651.26 KFM13253.1 - 2e-33 114.6 1.9 1.2e-32 112.1 0.2 2.2 1 1 1 2 2 2 1 BTB/POZ domain MATH PF00917.21 KFM13253.1 - 2e-10 40.9 0.1 7.2e-10 39.1 0.0 1.8 2 0 0 2 2 2 1 MATH domain BACK PF07707.10 KFM13253.1 - 0.0011 18.7 0.8 0.1 12.4 0.0 3.3 4 0 0 4 4 4 1 BTB And C-terminal Kelch UAA PF08449.6 KFM13254.1 - 1.3e-72 244.3 7.0 1.4e-72 244.1 4.8 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 KFM13254.1 - 1e-14 54.6 15.1 1.2e-09 38.2 7.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 KFM13254.1 - 3.8e-14 52.6 13.4 5.7e-12 45.5 6.2 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 KFM13254.1 - 1.3e-10 41.4 15.6 3.5e-06 27.1 0.1 2.1 2 0 0 2 2 2 2 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 KFM13254.1 - 0.0069 15.5 1.5 1.4 7.9 0.0 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter MOZ_SAS PF01853.13 KFM13255.1 - 2.9e-89 297.3 2.4 4.4e-89 296.7 1.7 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-C2HC PF01530.13 KFM13255.1 - 1.7e-14 53.1 4.5 1.7e-14 53.1 3.1 1.8 2 0 0 2 2 2 1 Zinc finger, C2HC type Palm_thioest PF02089.10 KFM13255.1 - 0.026 13.4 0.1 6 5.7 0.0 2.4 2 0 0 2 2 2 0 Palmitoyl protein thioesterase Acetyltransf_7 PF13508.1 KFM13255.1 - 0.039 14.0 0.0 1.3 9.2 0.0 2.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain zf-met PF12874.2 KFM13255.1 - 0.046 13.9 0.4 0.14 12.3 0.3 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Pkinase_Tyr PF07714.12 KFM13256.1 - 9e-96 319.9 0.0 1e-95 319.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM13256.1 - 2.5e-47 161.2 0.0 3e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.1 KFM13256.1 - 5e-15 55.6 1.1 8.6e-15 54.9 0.8 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Kdo PF06293.9 KFM13256.1 - 0.044 12.8 0.0 0.063 12.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ion_trans PF00520.26 KFM13257.1 - 7.4e-47 159.1 44.1 1.3e-46 158.4 12.4 2.7 3 0 0 3 3 3 2 Ion transport protein PKD_channel PF08016.7 KFM13257.1 - 3e-08 32.5 21.3 4.1e-08 32.0 1.5 3.1 2 1 1 3 3 3 2 Polycystin cation channel IQ PF00612.22 KFM13257.1 - 0.00037 19.8 0.7 0.00081 18.8 0.5 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif NPCC PF08058.6 KFM13257.1 - 0.038 13.8 2.0 0.5 10.2 0.0 3.0 2 1 1 3 3 3 0 Nuclear pore complex component FixQ PF05545.6 KFM13257.1 - 3.6 7.3 8.8 1.6 8.4 0.1 3.3 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Ion_trans PF00520.26 KFM13258.1 - 1.6e-217 716.3 99.4 2.9e-73 245.3 7.7 5.1 5 0 0 5 5 5 4 Ion transport protein Na_trans_assoc PF06512.8 KFM13258.1 - 5.9e-69 232.6 3.3 5.9e-69 232.6 2.3 1.8 2 0 0 2 2 2 1 Sodium ion transport-associated DUF3451 PF11933.3 KFM13258.1 - 2.2e-39 135.6 1.4 2.2e-39 135.6 1.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3451) PKD_channel PF08016.7 KFM13258.1 - 4.9e-13 48.2 77.9 9.6e-08 30.8 0.3 10.0 6 4 3 10 10 10 8 Polycystin cation channel IQ PF00612.22 KFM13258.1 - 0.0016 17.9 1.2 0.0042 16.6 0.9 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif Endonuclease_NS PF01223.18 KFM13259.1 - 4e-53 180.1 0.0 4.9e-53 179.8 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Pkinase PF00069.20 KFM13260.1 - 5.8e-56 189.5 0.0 7.8e-56 189.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM13260.1 - 5.1e-26 91.2 0.0 8.3e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Activin_recp PF01064.18 KFM13260.1 - 2e-11 44.3 13.6 2e-11 44.3 9.4 2.1 2 0 0 2 2 2 1 Activin types I and II receptor domain FGGY_C PF02782.11 KFM13262.1 - 5.4e-12 45.7 0.0 6.4e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KFM13263.1 - 2.7e-18 66.1 0.0 5.8e-14 52.0 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 KFM13263.1 - 7.3e-11 42.0 0.0 1.8e-10 40.7 0.0 1.7 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain UBA PF00627.26 KFM13265.1 - 4.8e-23 80.3 0.1 9.5e-07 28.4 0.0 3.8 3 0 0 3 3 3 3 UBA/TS-N domain UBA_4 PF14555.1 KFM13265.1 - 2.3e-05 23.8 0.2 0.26 10.8 0.0 3.5 3 0 0 3 3 3 1 UBA-like domain Rap1_C PF11626.3 KFM13265.1 - 0.0014 18.4 0.2 11 5.9 0.0 4.0 4 0 0 4 4 4 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain ubiquitin PF00240.18 KFM13265.1 - 0.0025 17.1 0.8 0.011 15.1 0.6 2.0 2 0 0 2 2 2 1 Ubiquitin family TPR_2 PF07719.12 KFM13265.1 - 0.0029 17.3 10.4 0.078 12.9 0.7 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFM13265.1 - 0.0041 17.0 5.8 0.69 9.8 0.9 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat RuvA_C PF07499.8 KFM13265.1 - 0.014 15.5 0.0 20 5.4 0.0 3.7 3 0 0 3 3 3 0 RuvA, C-terminal domain BBE PF08031.7 KFM13265.1 - 0.12 12.3 0.0 0.52 10.2 0.0 2.1 2 0 0 2 2 2 0 Berberine and berberine like TPR_8 PF13181.1 KFM13265.1 - 0.17 11.7 2.1 5.1 7.1 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFM13265.1 - 0.62 9.7 6.1 5.6 6.7 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 KFM13265.1 - 0.68 9.6 4.9 10 5.8 0.2 3.1 2 1 0 2 2 2 0 TPR repeat Crystall PF00030.14 KFM13266.1 - 8.6e-56 185.7 3.9 4.2e-29 100.2 0.2 2.0 2 0 0 2 2 2 2 Beta/Gamma crystallin Crystall_3 PF08964.5 KFM13266.1 - 3.2e-05 23.5 0.1 0.12 12.1 0.0 3.3 3 1 0 3 3 3 2 Beta/Gamma crystallin WIYLD PF10440.4 KFM13266.1 - 0.1 12.5 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-binding WIYLD domain Ras PF00071.17 KFM13267.1 - 7e-43 145.8 0.4 8.2e-43 145.5 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM13267.1 - 1e-12 48.6 0.1 1.9e-12 47.7 0.1 1.5 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KFM13267.1 - 2.7e-05 23.6 0.1 3.3e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 KFM13267.1 - 6.5e-05 22.2 0.1 6.9e-05 22.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFM13267.1 - 0.017 15.1 0.1 0.024 14.5 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase CBS PF00571.23 KFM13268.1 - 2.4e-37 126.4 2.7 1.7e-10 40.5 0.3 4.3 4 0 0 4 4 4 4 CBS domain RVT_1 PF00078.22 KFM13269.1 - 0.0093 15.3 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glycos_transf_2 PF00535.21 KFM13270.1 - 1.8e-27 96.0 0.0 3.1e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 KFM13270.1 - 3.1e-21 75.6 2.9 5.5e-21 74.8 2.0 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.1 KFM13270.1 - 9.2e-10 38.7 0.0 3.5e-09 36.8 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 KFM13270.1 - 3.2e-07 29.7 0.1 7.7e-07 28.4 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFM13270.1 - 7.2e-06 25.2 0.0 2.1e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.1 KFM13270.1 - 0.00015 22.1 0.0 0.0019 18.5 0.0 2.4 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Rad51 PF08423.6 KFM13271.1 - 4.2e-15 55.3 0.0 5.7e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KFM13271.1 - 0.00011 21.7 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 KFM13271.1 - 0.0077 15.3 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_19 PF13245.1 KFM13271.1 - 0.016 14.9 0.0 0.034 13.8 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 KFM13271.1 - 0.04 13.5 0.4 0.48 10.0 0.3 2.2 1 1 0 1 1 1 0 NACHT domain Actin PF00022.14 KFM13272.1 - 1.6e-88 296.8 0.0 4.5e-88 295.3 0.0 1.6 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KFM13272.1 - 1.7e-05 23.6 0.0 0.032 12.8 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein Robl_LC7 PF03259.12 KFM13272.1 - 0.013 15.0 0.1 0.034 13.6 0.0 1.6 2 0 0 2 2 2 0 Roadblock/LC7 domain DPPIV_N PF00930.16 KFM13273.1 - 3.1e-112 374.6 0.2 4.6e-112 374.1 0.2 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 KFM13273.1 - 1.2e-35 122.7 0.1 2e-35 121.9 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.7 KFM13273.1 - 9.4e-06 25.1 0.2 0.048 13.3 0.0 3.0 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat DLH PF01738.13 KFM13273.1 - 2.1e-05 23.9 1.3 0.0001 21.6 0.9 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KFM13273.1 - 0.00077 19.2 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PTCB-BRCT PF12738.2 KFM13274.1 - 1.7e-55 184.6 1.9 6.8e-21 73.8 0.0 4.9 5 0 0 5 5 5 4 twin BRCT domain BRCT PF00533.21 KFM13274.1 - 1.9e-53 178.5 1.2 1.6e-11 44.2 0.1 6.2 6 0 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain 7tm_1 PF00001.16 KFM13275.1 - 2.3e-77 259.6 9.5 2.3e-77 259.6 6.6 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) DUF3357 PF11837.3 KFM13275.1 - 0.27 11.1 1.5 4 7.3 0.2 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF3357) DUF3278 PF11683.3 KFM13275.1 - 0.71 9.8 0.0 0.71 9.8 0.0 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF3278) DUF3135 PF11333.3 KFM13276.1 - 0.1 12.7 0.0 0.17 12.0 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3135) INSIG PF07281.7 KFM13277.1 - 1.2e-56 191.0 0.9 1.4e-56 190.9 0.6 1.0 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) DUF3456 PF11938.3 KFM13278.1 - 0.0015 18.5 0.0 0.0015 18.5 0.0 1.0 1 0 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP SapB_2 PF03489.12 KFM13278.1 - 0.062 13.3 0.0 0.083 12.9 0.0 1.2 1 0 0 1 1 1 0 Saposin-like type B, region 2 TRAPP PF04051.11 KFM13280.1 - 1.7e-39 134.7 0.0 2e-39 134.5 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Fork_head PF00250.13 KFM13281.1 - 4.1e-46 154.9 0.1 4.5e-46 154.8 0.0 1.0 1 0 0 1 1 1 1 Fork head domain BNIP2 PF12496.3 KFM13282.1 - 1.1e-40 138.6 2.0 1.7e-40 138.1 1.4 1.3 1 0 0 1 1 1 1 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 CRAL_TRIO_2 PF13716.1 KFM13282.1 - 3.5e-28 98.3 0.1 5.5e-28 97.7 0.1 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 KFM13282.1 - 6.2e-09 35.5 0.0 9.3e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain TFIIA_gamma_N PF02268.11 KFM13283.1 - 2.1e-24 84.8 0.5 2.9e-24 84.3 0.3 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 KFM13283.1 - 5.7e-24 83.6 2.6 8.1e-24 83.1 1.8 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit HAD_2 PF13419.1 KFM13284.1 - 9.9e-22 77.9 0.0 1.1e-21 77.7 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFM13284.1 - 2e-06 27.4 0.0 3.6e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KFM13284.1 - 0.00024 21.5 0.0 0.00029 21.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFM13284.1 - 0.017 15.3 0.0 0.018 15.1 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 KFM13284.1 - 0.14 12.0 0.0 0.4 10.6 0.0 1.7 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Sulfatase PF00884.18 KFM13285.1 - 4.3e-92 308.5 0.0 5.3e-92 308.2 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 KFM13285.1 - 1.2e-44 151.7 0.6 2.2e-44 150.9 0.4 1.4 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.17 KFM13285.1 - 5.5e-10 39.1 0.0 2.3e-09 37.0 0.0 1.8 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Patatin PF01734.17 KFM13286.1 - 4.4e-16 59.4 0.7 8.7e-15 55.1 0.5 2.1 1 1 0 1 1 1 1 Patatin-like phospholipase fn3 PF00041.16 KFM13287.1 - 2.4e-37 126.9 11.0 1.6e-14 53.7 0.1 4.3 4 0 0 4 4 4 3 Fibronectin type III domain WAP PF00095.16 KFM13287.1 - 6.8e-10 38.7 15.4 6.8e-10 38.7 10.7 2.7 2 1 0 2 2 2 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Interfer-bind PF09294.5 KFM13287.1 - 0.00013 21.9 3.3 0.00093 19.2 0.1 3.1 3 0 0 3 3 3 1 Interferon-alpha/beta receptor, fibronectin type III Vif PF00559.12 KFM13287.1 - 0.0075 16.1 0.4 0.054 13.3 0.0 2.3 2 0 0 2 2 2 1 Retroviral Vif (Viral infectivity) protein WD40 PF00400.27 KFM13288.1 - 1.8e-70 230.5 28.5 1.9e-13 49.6 0.2 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat eIF2A PF08662.6 KFM13288.1 - 6.7e-12 45.5 0.6 0.0015 18.2 0.0 3.6 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 KFM13288.1 - 0.00066 19.1 0.0 8.7 5.9 0.0 4.6 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.3 KFM13288.1 - 0.00074 17.7 1.9 0.021 12.9 0.0 3.1 2 1 1 3 3 3 1 Nucleoporin Nup120/160 IKI3 PF04762.7 KFM13288.1 - 0.02 12.7 1.8 0.089 10.5 0.2 2.6 1 1 2 3 3 3 0 IKI3 family Ocular_alb PF02101.10 KFM13289.1 - 7e-171 568.2 8.3 8.6e-171 567.9 5.8 1.0 1 0 0 1 1 1 1 Ocular albinism type 1 protein 7tm_2 PF00002.19 KFM13289.1 - 1.1e-05 24.6 7.2 2e-05 23.8 5.0 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.16 KFM13289.1 - 0.067 12.3 12.9 0.2 10.7 8.6 2.0 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) ASD2 PF08687.6 KFM13290.1 - 4e-112 373.8 22.6 4e-112 373.8 15.6 3.3 3 1 1 4 4 4 1 Apx/Shroom domain ASD2 ASD1 PF08688.5 KFM13290.1 - 2.1e-54 184.0 4.9 2.1e-54 184.0 3.4 4.8 5 0 0 5 5 5 2 Apx/Shroom domain ASD1 Claudin_2 PF13903.1 KFM13291.1 - 2e-07 30.8 10.3 2.6e-07 30.5 7.1 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 KFM13291.1 - 1.4e-06 28.0 10.5 2.3e-06 27.3 7.3 1.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family RVT_1 PF00078.22 KFM13293.1 - 0.066 12.5 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Voltage_CLC PF00654.15 KFM13294.1 - 4.7e-102 341.6 17.4 4.7e-102 341.6 12.1 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 KFM13294.1 - 8.6e-16 57.4 0.7 5.2e-09 35.7 0.1 2.6 2 0 0 2 2 2 2 CBS domain SPRY PF00622.23 KFM13295.1 - 2e-18 66.6 0.0 3.7e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 SPRY domain PRY PF13765.1 KFM13295.1 - 6.1e-11 41.6 0.2 2.1e-10 39.9 0.0 2.1 2 0 0 2 2 1 1 SPRY-associated domain zf-B_box PF00643.19 KFM13295.1 - 1.7e-08 34.1 0.8 1.7e-08 34.1 0.6 5.2 6 1 0 6 6 5 2 B-box zinc finger fn3 PF00041.16 KFM13295.1 - 2.8e-08 33.7 0.2 6.4e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III domain zf-C3HC4_3 PF13920.1 KFM13295.1 - 9e-08 31.6 7.6 9e-08 31.6 5.2 4.1 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM13295.1 - 3.8e-07 30.0 11.6 3.8e-07 30.0 8.0 4.3 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFM13295.1 - 2.4e-06 27.3 12.3 2.4e-06 27.3 8.5 5.2 5 1 1 6 6 6 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KFM13295.1 - 3e-06 26.7 11.6 3e-06 26.7 8.1 4.1 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM13295.1 - 5.1e-06 26.2 11.8 5.1e-06 26.2 8.2 3.4 2 1 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KFM13295.1 - 0.00024 20.7 10.0 0.00024 20.7 7.0 4.5 4 1 1 5 5 5 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KFM13295.1 - 0.00032 20.3 7.2 0.00032 20.3 5.0 3.2 3 0 0 3 3 3 1 RING-type zinc-finger DNA_photolyase PF00875.13 KFM13295.1 - 0.18 11.5 1.9 0.23 11.1 0.3 1.9 2 0 0 2 2 2 0 DNA photolyase Baculo_PEP_C PF04513.7 KFM13295.1 - 0.31 10.8 6.2 0.082 12.7 0.5 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus LcrG PF07216.7 KFM13295.1 - 0.8 9.7 4.0 2.4 8.2 1.0 2.4 2 0 0 2 2 2 0 LcrG protein DNA_topoisoIV PF00521.15 KFM13295.1 - 2.4 6.9 8.4 3.7 6.2 5.8 1.2 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A RhoGAP PF00620.22 KFM13296.1 - 9.7e-48 161.6 0.0 2e-47 160.5 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain DUF1679 PF07914.6 KFM13296.1 - 0.043 12.4 0.0 0.075 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) MRG PF05712.8 KFM13298.1 - 6.3e-68 227.5 0.3 9.8e-68 226.8 0.2 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 KFM13298.1 - 4.8e-05 22.9 0.4 0.00012 21.6 0.3 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF2828 PF11443.3 KFM13298.1 - 0.039 12.1 1.3 0.052 11.7 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Chromo PF00385.19 KFM13298.1 - 0.054 13.1 0.2 0.14 11.8 0.1 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain CDC45 PF02724.9 KFM13298.1 - 8.9 4.1 13.6 14 3.5 9.5 1.3 1 0 0 1 1 1 0 CDC45-like protein zf-U11-48K PF05253.7 KFM13299.1 - 6e-23 80.1 10.7 1.6e-11 43.6 0.1 2.2 2 0 0 2 2 2 2 U11-48K-like CHHC zinc finger V-SNARE_C PF12352.3 KFM13300.1 - 1.1e-17 63.8 4.6 1.4e-17 63.5 1.0 2.4 1 1 1 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KFM13300.1 - 1.8e-05 24.3 0.1 4.3e-05 23.1 0.1 1.7 1 0 0 1 1 1 1 Sec20 Ran-binding PF05508.6 KFM13300.1 - 0.0023 16.8 1.9 0.0033 16.3 1.3 1.2 1 0 0 1 1 1 1 RanGTP-binding protein V-SNARE PF05008.10 KFM13300.1 - 0.0037 17.3 1.6 0.0093 16.1 1.1 1.7 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus SLX9 PF15341.1 KFM13300.1 - 0.047 14.1 0.8 0.058 13.8 0.6 1.3 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 GP41 PF00517.12 KFM13300.1 - 0.31 10.5 2.0 0.75 9.3 1.0 1.9 1 1 0 1 1 1 0 Retroviral envelope protein Fmp27_WPPW PF10359.4 KFM13300.1 - 1.4 7.1 7.6 1.2 7.4 3.9 1.7 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain IncA PF04156.9 KFM13300.1 - 1.5 8.3 7.3 2.6 7.5 4.9 1.7 1 1 0 1 1 1 0 IncA protein wnt PF00110.14 KFM13302.1 - 5.9e-121 403.4 15.8 6.7e-121 403.2 10.9 1.0 1 0 0 1 1 1 1 wnt family AAA PF00004.24 KFM13303.1 - 1.1e-57 193.8 0.0 1.2e-41 142.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 KFM13303.1 - 1.1e-14 54.0 0.0 2.1e-13 50.0 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.12 KFM13303.1 - 2.2e-14 52.8 4.3 2.5e-14 52.6 0.1 2.8 3 0 0 3 3 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.1 KFM13303.1 - 9.3e-10 38.7 0.3 0.0022 18.1 0.1 4.2 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KFM13303.1 - 1.2e-09 39.0 0.0 0.0015 19.3 0.0 2.9 2 1 0 3 3 2 2 AAA domain AAA_14 PF13173.1 KFM13303.1 - 4e-09 36.4 0.0 0.0033 17.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 KFM13303.1 - 3.9e-08 33.4 0.1 0.011 15.9 0.0 3.5 4 0 0 4 4 2 2 RNA helicase AAA_2 PF07724.9 KFM13303.1 - 4.6e-08 33.1 0.0 6e-06 26.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KFM13303.1 - 2.2e-07 30.6 0.1 0.00073 19.2 0.1 3.4 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KFM13303.1 - 4.1e-07 29.2 0.0 0.0099 14.9 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 KFM13303.1 - 7.4e-07 29.1 0.0 0.053 13.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 KFM13303.1 - 5.3e-06 25.4 0.0 0.079 11.6 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus AAA_16 PF13191.1 KFM13303.1 - 5.5e-06 26.4 0.0 0.0051 16.8 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 KFM13303.1 - 6.7e-06 26.4 0.0 0.019 15.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KFM13303.1 - 7e-06 25.6 0.1 0.12 12.1 0.0 3.0 3 0 0 3 3 3 2 Part of AAA domain Mg_chelatase PF01078.16 KFM13303.1 - 9.6e-06 24.8 0.1 0.0035 16.5 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 KFM13303.1 - 3.5e-05 23.0 0.0 0.27 10.2 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin NACHT PF05729.7 KFM13303.1 - 9e-05 22.1 0.0 0.63 9.6 0.0 3.6 3 1 0 3 3 3 2 NACHT domain Arch_ATPase PF01637.13 KFM13303.1 - 0.00023 20.9 0.1 0.24 11.0 0.0 3.4 2 2 2 4 4 4 1 Archaeal ATPase KTI12 PF08433.5 KFM13303.1 - 0.00044 19.5 0.4 1 8.4 0.0 3.2 3 0 0 3 3 3 2 Chromatin associated protein KTI12 KaiC PF06745.8 KFM13303.1 - 0.00086 18.4 0.1 0.016 14.3 0.0 2.8 2 1 1 3 3 3 1 KaiC AAA_28 PF13521.1 KFM13303.1 - 0.001 19.0 0.0 0.24 11.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KFM13303.1 - 0.001 18.4 0.3 1 8.6 0.0 3.5 2 1 1 3 3 3 1 AAA domain AAA_3 PF07726.6 KFM13303.1 - 0.0015 18.1 0.0 0.28 10.8 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KFM13303.1 - 0.0019 17.6 0.1 0.15 11.5 0.0 2.7 3 0 0 3 3 3 1 IstB-like ATP binding protein Sigma54_activat PF00158.21 KFM13303.1 - 0.0027 17.2 0.0 1.3 8.4 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain UPF0079 PF02367.12 KFM13303.1 - 0.0031 17.1 0.1 0.44 10.1 0.0 2.8 3 0 0 3 3 2 1 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 KFM13303.1 - 0.0031 17.7 0.1 0.014 15.7 0.0 2.1 2 0 0 2 2 1 1 ABC transporter AAA_24 PF13479.1 KFM13303.1 - 0.0074 15.8 0.1 0.11 12.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.12 KFM13303.1 - 0.01 14.6 0.1 1.8 7.3 0.0 2.8 4 0 0 4 4 3 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 KFM13303.1 - 0.012 14.4 0.0 0.44 9.3 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain VirE PF05272.6 KFM13303.1 - 0.038 13.4 0.0 0.69 9.3 0.0 2.9 3 0 0 3 3 3 0 Virulence-associated protein E CPT PF07931.7 KFM13303.1 - 0.057 13.0 0.0 1 8.9 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Sigma54_activ_2 PF14532.1 KFM13303.1 - 0.078 13.0 0.2 12 5.9 0.0 3.2 3 1 0 3 3 2 0 Sigma-54 interaction domain DicB PF05358.6 KFM13304.1 - 0.0023 17.3 1.3 0.07 12.6 0.1 2.7 2 0 0 2 2 2 1 DicB protein DUF3318 PF11780.3 KFM13304.1 - 0.017 14.7 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) DUF1539 PF07560.6 KFM13304.1 - 0.39 10.5 4.7 0.18 11.6 0.2 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) zf-DBF PF07535.7 KFM13305.1 - 1.2e-17 63.2 0.2 2.7e-17 62.1 0.2 1.6 1 0 0 1 1 1 1 DBF zinc finger zf-C2H2_2 PF12756.2 KFM13305.1 - 0.039 14.0 0.2 0.077 13.1 0.2 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) RNA_pol_Rpc82 PF05645.8 KFM13305.1 - 0.057 12.9 0.0 0.057 12.9 0.0 1.7 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 Reprolysin PF01421.14 KFM13306.1 - 2.6e-60 203.4 0.0 5.4e-60 202.4 0.0 1.5 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.7 KFM13306.1 - 3.8e-25 88.2 4.6 3.8e-25 88.2 3.2 3.7 3 1 0 4 4 4 1 ADAM cysteine-rich Disintegrin PF00200.18 KFM13306.1 - 2.1e-18 66.2 29.0 2.1e-18 66.2 20.1 3.3 3 0 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.1 KFM13306.1 - 2.1e-10 41.2 0.1 3.7e-10 40.3 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KFM13306.1 - 1.2e-09 38.3 0.2 2.6e-09 37.3 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 KFM13306.1 - 5.9e-06 26.4 0.1 3e-05 24.1 0.1 2.1 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFM13306.1 - 6.4e-05 22.5 0.0 0.00014 21.4 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like EGF_2 PF07974.8 KFM13306.1 - 0.00023 21.2 10.5 0.00023 21.2 7.3 6.3 5 1 0 5 5 5 1 EGF-like domain hEGF PF12661.2 KFM13306.1 - 0.027 14.5 0.7 0.027 14.5 0.5 4.7 5 0 0 5 5 5 0 Human growth factor-like EGF Connexin PF00029.14 KFM13307.1 - 1e-50 170.2 0.9 1.9e-50 169.4 0.6 1.4 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 KFM13307.1 - 1.1e-32 111.6 4.2 2.5e-32 110.4 2.9 1.7 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain DUF4407 PF14362.1 KFM13307.1 - 1.1 8.1 4.8 2.7 6.8 3.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) GTP_EFTU PF00009.22 KFM13309.1 - 4.8e-43 146.7 0.0 7.2e-43 146.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KFM13309.1 - 1.2e-26 92.6 0.0 2.6e-26 91.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 KFM13309.1 - 1.1e-21 76.4 0.0 3.1e-21 75.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KFM13309.1 - 1.9e-11 43.9 0.1 5.3e-11 42.4 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KFM13309.1 - 2.1e-08 33.9 0.0 5.4e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II Miro PF08477.8 KFM13309.1 - 4.2e-05 24.0 0.0 9.1e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Septin PF00735.13 KFM13309.1 - 0.091 11.7 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Septin Nop14 PF04147.7 KFM13309.1 - 9.7 3.9 6.4 14 3.4 4.5 1.1 1 0 0 1 1 1 0 Nop14-like family RPAP3_C PF13877.1 KFM13310.1 - 3.8e-21 74.8 0.0 6.1e-21 74.2 0.0 1.3 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 V-set PF07686.12 KFM13311.1 - 1.2e-11 44.4 0.0 2.3e-06 27.4 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin V-set domain ig PF00047.20 KFM13311.1 - 1.5e-05 24.9 0.4 0.26 11.4 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.1 KFM13311.1 - 4e-05 23.6 0.0 0.14 12.2 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 KFM13311.1 - 5.8e-05 22.8 0.0 0.081 12.7 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin I-set domain Receptor_2B4 PF11465.3 KFM13311.1 - 0.059 13.2 0.0 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 Kinesin PF00225.18 KFM13312.1 - 1.2e-104 349.6 0.1 1.7e-104 349.1 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain C1q PF00386.16 KFM13314.1 - 1.4e-17 63.9 0.0 1.5e-17 63.7 0.0 1.0 1 0 0 1 1 1 1 C1q domain TNF PF00229.13 KFM13314.1 - 0.078 12.5 0.0 0.088 12.3 0.0 1.1 1 0 0 1 1 1 0 TNF(Tumour Necrosis Factor) family CoaE PF01121.15 KFM13315.1 - 1.8e-61 206.6 0.0 2.3e-61 206.3 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.1 KFM13315.1 - 5.9e-06 26.6 0.1 1.9e-05 24.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFM13315.1 - 0.00012 22.8 0.1 0.00022 22.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFM13315.1 - 0.00083 19.2 0.0 0.0053 16.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFM13315.1 - 0.0047 16.9 0.1 0.0078 16.2 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.1 KFM13315.1 - 0.0097 15.8 0.2 0.041 13.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.1 KFM13315.1 - 0.092 12.6 0.1 0.56 10.0 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase-like family NMT_C PF02799.10 KFM13316.1 - 4.1e-85 283.9 0.0 5.7e-85 283.5 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 KFM13316.1 - 1e-82 275.5 0.0 1.6e-82 274.8 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_3 PF13302.1 KFM13316.1 - 0.017 15.2 0.0 0.53 10.4 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFM13316.1 - 0.021 14.6 0.0 0.068 13.0 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KFM13316.1 - 0.028 14.5 0.0 0.063 13.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFM13316.1 - 0.1 12.6 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family PI-PLC-X PF00388.14 KFM13317.1 - 2e-68 228.3 0.0 3.9e-68 227.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KFM13317.1 - 3.3e-42 143.2 0.0 6.6e-42 142.2 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_10 PF14788.1 KFM13317.1 - 5e-24 83.7 1.4 1.6e-23 82.1 0.4 2.2 2 0 0 2 2 2 1 EF hand EF-hand_like PF09279.6 KFM13317.1 - 1.8e-20 72.7 0.3 5.2e-20 71.2 0.2 1.9 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 KFM13317.1 - 1.1e-16 60.3 0.0 2.1e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain EF-hand_6 PF13405.1 KFM13317.1 - 7.2e-06 25.4 1.3 3.1 7.9 0.1 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.1 KFM13317.1 - 3.2e-05 23.9 0.7 0.013 15.6 0.1 2.7 1 1 1 2 2 2 1 EF-hand domain pair PH PF00169.24 KFM13317.1 - 0.00013 22.1 0.0 0.00026 21.1 0.0 1.6 1 0 0 1 1 1 1 PH domain EF-hand_1 PF00036.27 KFM13317.1 - 0.00068 18.7 0.1 0.073 12.4 0.0 3.3 3 0 0 3 3 3 1 EF hand GDPD PF03009.12 KFM13317.1 - 0.00099 18.6 0.0 0.0025 17.3 0.0 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF3682 PF12446.3 KFM13317.1 - 0.67 10.2 6.4 1.4 9.2 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Lamprin PF06403.6 KFM13318.1 - 5.9e-05 22.8 5.4 7.1e-05 22.5 3.7 1.2 1 0 0 1 1 1 1 Lamprin Chorion_1 PF01723.11 KFM13318.1 - 4.4 7.1 6.7 18 5.1 4.6 1.8 1 1 0 1 1 1 0 Chorion protein Pkinase PF00069.20 KFM13319.1 - 4.9e-22 78.3 0.0 5.8e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM13319.1 - 1.7e-06 27.3 0.0 2.2e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM13320.1 - 5.6e-46 156.8 0.0 8.3e-46 156.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM13320.1 - 5.8e-29 100.9 0.0 8.9e-29 100.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Myosin_head PF00063.16 KFM13321.1 - 1.8e-230 766.6 6.3 2.4e-230 766.2 4.3 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 KFM13321.1 - 5.5e-46 156.3 0.2 2e-45 154.5 0.1 1.9 2 0 0 2 2 2 1 Myosin tail AAA_18 PF13238.1 KFM13321.1 - 0.0019 18.4 0.0 0.0089 16.3 0.0 2.2 1 0 0 1 1 1 1 AAA domain IQ PF00612.22 KFM13321.1 - 0.0048 16.4 4.9 0.0073 15.8 0.4 2.8 2 0 0 2 2 2 1 IQ calmodulin-binding motif AAA_22 PF13401.1 KFM13321.1 - 0.0081 16.3 0.1 0.029 14.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KFM13321.1 - 0.013 14.5 0.3 0.042 12.9 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.1 KFM13321.1 - 0.018 15.8 0.2 0.36 11.6 0.0 3.2 4 0 0 4 4 4 0 AAA domain PCI PF01399.22 KFM13322.1 - 2e-20 73.0 0.6 2e-20 73.0 0.4 2.3 3 0 0 3 3 3 1 PCI domain DDRGK PF09756.4 KFM13322.1 - 0.0021 17.5 0.1 0.005 16.2 0.1 1.6 1 0 0 1 1 1 1 DDRGK domain TPR_10 PF13374.1 KFM13322.1 - 0.18 11.8 0.1 0.18 11.8 0.1 3.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 KFM13322.1 - 0.19 11.7 6.7 13 5.9 0.1 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 KFM13322.1 - 0.41 10.6 12.7 1.1 9.1 1.7 4.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFM13322.1 - 7.2 6.6 7.9 30 4.7 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Frizzled PF01534.12 KFM13323.1 - 6.4e-149 495.1 17.3 7.9e-149 494.8 12.0 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.17 KFM13323.1 - 1.4e-34 118.9 5.8 2.6e-34 118.0 4.0 1.5 1 0 0 1 1 1 1 Fz domain Ndc1_Nup PF09531.5 KFM13323.1 - 0.0056 15.1 1.6 0.0088 14.5 1.1 1.2 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup zf-DHHC PF01529.15 KFM13323.1 - 1.8 7.9 11.3 1.1 8.6 1.1 3.1 3 0 0 3 3 3 0 DHHC palmitoyltransferase Integrin_alpha2 PF08441.7 KFM13324.1 - 4.5e-24 85.1 0.0 1.9e-11 43.5 0.0 2.0 1 1 1 2 2 2 2 Integrin alpha Granulin PF00396.13 KFM13325.1 - 9.2e-35 118.4 99.3 8.7e-18 64.1 14.5 7.6 5 3 3 8 8 8 7 Granulin RhoGAP PF00620.22 KFM13326.1 - 1.4e-34 118.8 0.0 1.8e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain SH3_9 PF14604.1 KFM13327.1 - 3.9e-08 32.7 0.1 4.7e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFM13327.1 - 2.8e-05 23.4 0.0 3.4e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 SH3 domain DUF4206 PF13901.1 KFM13328.1 - 6.7e-70 234.7 14.6 1.3e-69 233.7 10.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4206) RUN PF02759.14 KFM13328.1 - 2.6e-24 85.4 0.1 5.1e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 RUN domain PH PF00169.24 KFM13328.1 - 3e-05 24.1 0.0 0.17 12.0 0.0 2.6 2 0 0 2 2 2 2 PH domain Prok-RING_1 PF14446.1 KFM13328.1 - 0.0024 17.5 7.5 0.0024 17.5 5.2 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 1 Hydantoinase_B PF02538.9 KFM13328.1 - 0.48 8.6 0.0 0.71 8.0 0.0 1.1 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase zf-UDP PF14569.1 KFM13328.1 - 1 9.1 8.3 1.5 8.5 4.7 2.0 2 0 0 2 2 2 0 Zinc-binding RING-finger C1_1 PF00130.17 KFM13328.1 - 6.5 6.5 19.1 5.4 6.8 8.2 2.9 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rad52_Rad22 PF04098.10 KFM13329.1 - 7.3e-09 35.5 0.0 1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein RRM_5 PF13893.1 KFM13329.1 - 6.8e-06 25.8 0.0 1.3e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFM13329.1 - 2.4e-05 23.8 0.1 0.00013 21.5 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1953 PF09196.5 KFM13329.1 - 9e-05 22.1 0.0 0.00019 21.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1953) RRM_6 PF14259.1 KFM13329.1 - 0.001 19.0 0.0 0.0026 17.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Frankia_peptide PF14407.1 KFM13329.1 - 0.044 13.5 1.8 25 4.7 0.0 3.3 2 1 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. Hormone_1 PF00103.15 KFM13330.1 - 8.7e-47 159.2 0.0 1e-46 158.9 0.0 1.0 1 0 0 1 1 1 1 Somatotropin hormone family V-set PF07686.12 KFM13331.1 - 8e-07 28.9 0.0 1.5e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 KFM13331.1 - 7e-06 25.8 0.0 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain ITAM PF02189.10 KFM13331.1 - 0.0049 17.0 0.1 0.0049 17.0 0.1 1.8 2 0 0 2 2 2 1 Immunoreceptor tyrosine-based activation motif ig PF00047.20 KFM13331.1 - 0.011 15.8 0.1 0.027 14.5 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin domain Ig_2 PF13895.1 KFM13331.1 - 0.019 15.0 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain 7tm_2 PF00002.19 KFM13332.1 - 1.8e-78 262.9 19.4 2.3e-78 262.6 13.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 KFM13332.1 - 3.6e-16 58.9 1.9 3.6e-16 58.9 1.3 2.3 3 0 0 3 3 3 1 Hormone receptor domain Acyltransferase PF01553.16 KFM13333.1 - 9e-13 47.8 0.0 1e-12 47.6 0.0 1.0 1 0 0 1 1 1 1 Acyltransferase Acyltransferase PF01553.16 KFM13334.1 - 1.3e-11 44.0 0.0 1.5e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Acyltransferase YlqD PF11068.3 KFM13335.1 - 0.023 14.7 0.5 0.023 14.7 0.3 2.1 2 0 0 2 2 2 0 YlqD protein Microtub_bind PF13931.1 KFM13335.1 - 3.6 7.7 8.6 2.7 8.1 1.4 2.5 2 1 1 3 3 3 0 Kinesin-associated microtubule-binding ATP-synt_E PF05680.7 KFM13335.1 - 3.7 7.5 13.8 2.9 7.8 3.2 2.2 2 0 0 2 2 2 0 ATP synthase E chain SWIB PF02201.13 KFM13336.1 - 1.1e-21 76.2 0.1 2.6e-21 75.0 0.0 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain ASC PF00858.19 KFM13337.1 - 2.1e-64 217.8 2.4 5.1e-50 170.4 0.8 2.0 1 1 1 2 2 2 2 Amiloride-sensitive sodium channel RVT_1 PF00078.22 KFM13338.1 - 9.1e-20 70.9 0.0 1.2e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Gag_p30 PF02093.11 KFM13339.1 - 7.2e-18 64.5 0.1 8.7e-18 64.3 0.0 1.0 1 0 0 1 1 1 1 Gag P30 core shell protein Gag_p24 PF00607.15 KFM13339.1 - 0.036 13.6 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) ASC PF00858.19 KFM13340.1 - 7e-30 104.0 0.0 8e-30 103.8 0.0 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel 7tm_2 PF00002.19 KFM13341.1 - 4.8e-77 258.3 22.0 5.9e-77 258.0 15.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 KFM13341.1 - 5.7e-18 64.6 2.7 6.4e-18 64.5 1.1 1.8 2 0 0 2 2 2 1 Hormone receptor domain DUF2976 PF11190.3 KFM13341.1 - 0.37 10.3 4.0 4.7 6.8 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Sp38 PF07354.7 KFM13342.1 - 1.1e-12 47.2 0.2 1.4e-12 46.8 0.1 1.1 1 0 0 1 1 1 1 Zona-pellucida-binding protein (Sp38) V-set PF07686.12 KFM13342.1 - 0.00049 19.9 0.1 0.009 15.8 0.1 2.5 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 KFM13342.1 - 0.00055 19.9 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 KFM13342.1 - 0.067 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin I-set domain ig PF00047.20 KFM13342.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain GCC2_GCC3 PF07699.8 KFM13343.1 - 6.6e-05 22.4 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 GCC2 and GCC3 O-ag_pol_Wzy PF14296.1 KFM13343.1 - 0.035 12.6 0.3 0.045 12.3 0.2 1.0 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy DUF1072 PF06380.6 KFM13344.1 - 0.097 12.3 7.2 0.35 10.5 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) Tmemb_9 PF05434.6 KFM13344.1 - 0.14 11.8 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 TMEM9 Integrin_beta PF00362.13 KFM13345.1 - 1.3e-181 604.1 0.1 1.3e-181 604.1 0.1 1.7 2 0 0 2 2 2 1 Integrin, beta chain Integrin_b_cyt PF08725.6 KFM13345.1 - 5.2e-24 83.3 2.0 9.9e-24 82.4 0.1 2.4 3 0 0 3 3 3 1 Integrin beta cytoplasmic domain Integrin_B_tail PF07965.7 KFM13345.1 - 1.4e-21 76.6 8.8 1.4e-21 76.6 6.1 4.5 3 1 1 4 4 4 1 Integrin beta tail domain EGF_2 PF07974.8 KFM13345.1 - 1.6e-10 40.9 101.2 2.6e-05 24.3 11.6 6.7 5 1 1 6 6 6 4 EGF-like domain RNA_pol_A_CTD PF03118.10 KFM13345.1 - 0.04 13.3 0.2 0.13 11.7 0.1 1.8 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain Methyltransf_23 PF13489.1 KFM13346.1 - 1.9e-15 56.9 0.0 2.9e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFM13346.1 - 8.1e-14 51.9 0.0 1.6e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFM13346.1 - 3.9e-12 46.4 0.0 8.9e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFM13346.1 - 4.2e-11 42.6 0.0 7.1e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFM13346.1 - 1.3e-08 35.1 0.0 2.3e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFM13346.1 - 6.5e-08 33.1 0.0 1.3e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFM13346.1 - 5.2e-06 25.7 0.0 1.9e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KFM13346.1 - 0.00049 20.1 0.0 0.00099 19.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFM13346.1 - 0.0011 18.4 0.0 0.0017 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain TPMT PF05724.6 KFM13346.1 - 0.023 14.1 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_20 PF12147.3 KFM13346.1 - 0.035 12.9 0.0 0.22 10.3 0.0 2.1 1 1 0 1 1 1 0 Putative methyltransferase Methyltransf_8 PF05148.10 KFM13346.1 - 0.044 13.4 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase CheR PF01739.13 KFM13346.1 - 0.052 12.8 0.1 2.2 7.5 0.0 2.2 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain FmrO PF07091.6 KFM13346.1 - 0.1 11.5 0.1 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) DUF3298 PF11738.3 KFM13346.1 - 0.34 11.4 1.5 12 6.4 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3298) Pkinase PF00069.20 KFM13347.1 - 4.7e-60 202.9 0.0 1.2e-59 201.5 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM13347.1 - 1.8e-36 125.5 0.0 6.9e-36 123.6 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Vir_act_alpha_C PF10400.4 KFM13347.1 - 6.6 7.1 14.8 3.1 8.2 1.5 4.1 3 1 0 3 3 3 0 Virulence activator alpha C-term Ank_2 PF12796.2 KFM13349.1 - 1.3e-82 272.2 14.6 7.1e-22 77.5 0.0 5.5 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KFM13349.1 - 6.4e-63 205.5 10.6 8.2e-08 31.6 0.0 11.6 11 0 0 11 11 11 11 Ankyrin repeat Ank_4 PF13637.1 KFM13349.1 - 1.9e-54 181.0 4.1 1.9e-09 37.8 0.0 7.6 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM13349.1 - 5.3e-42 137.6 1.4 0.00075 19.5 0.0 11.0 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.1 KFM13349.1 - 7e-42 140.5 7.7 1e-10 41.4 0.0 8.6 3 2 5 8 8 8 7 Ankyrin repeats (many copies) TPR_11 PF13414.1 KFM13349.1 - 4.2e-14 51.9 7.2 3.8e-09 36.0 1.4 2.5 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 KFM13349.1 - 3.6e-11 42.0 6.7 0.00081 19.1 0.9 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KFM13349.1 - 1e-07 31.2 8.2 0.00047 19.6 0.8 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFM13349.1 - 1.1e-06 28.7 1.0 0.00012 22.3 0.3 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFM13349.1 - 1.1e-06 27.9 0.9 0.019 14.7 0.3 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 KFM13349.1 - 3.5e-06 26.7 0.2 7.3e-05 22.5 0.2 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFM13349.1 - 2e-05 25.1 4.8 0.015 15.9 0.6 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFM13349.1 - 2.3e-05 24.6 1.1 0.00027 21.2 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFM13349.1 - 7e-05 22.6 1.0 0.0038 17.1 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat AAA_16 PF13191.1 KFM13349.1 - 0.00085 19.3 0.1 0.0028 17.6 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain Miro PF08477.8 KFM13349.1 - 0.035 14.6 0.0 0.087 13.3 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein TPR_17 PF13431.1 KFM13349.1 - 0.037 14.2 1.8 0.18 12.1 0.3 2.8 2 1 1 3 3 2 0 Tetratricopeptide repeat NACHT PF05729.7 KFM13349.1 - 0.075 12.6 0.3 8.3 6.0 0.0 2.6 2 0 0 2 2 2 0 NACHT domain TPR_7 PF13176.1 KFM13349.1 - 0.084 12.7 0.5 2.7 7.9 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KFM13349.1 - 0.66 10.5 5.9 10 6.8 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Cytochrom_B561 PF03188.11 KFM13350.1 - 2.1e-43 147.4 11.1 2.1e-43 147.4 7.7 1.4 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 Na_Ca_ex PF01699.19 KFM13350.1 - 0.074 12.6 6.1 0.036 13.6 1.7 2.2 1 1 1 2 2 2 0 Sodium/calcium exchanger protein DUF202 PF02656.10 KFM13350.1 - 0.13 12.4 0.5 0.13 12.4 0.4 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF202) Claudin_3 PF06653.6 KFM13350.1 - 0.3 10.8 7.9 3 7.5 0.3 2.3 1 1 1 2 2 2 0 Tight junction protein, Claudin-like DUF3040 PF11239.3 KFM13350.1 - 0.73 9.9 0.0 0.73 9.9 0.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3040) Peptidase_M2 PF01401.13 KFM13351.1 - 0 2072.6 23.7 0 1063.7 4.4 2.0 2 0 0 2 2 2 2 Angiotensin-converting enzyme Ion_trans PF00520.26 KFM13352.1 - 1.3e-19 70.2 5.2 2.5e-19 69.3 3.6 1.5 1 0 0 1 1 1 1 Ion transport protein PAS_9 PF13426.1 KFM13352.1 - 4.2e-19 68.8 0.0 8.7e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 PAS domain cNMP_binding PF00027.24 KFM13352.1 - 2.2e-13 49.8 0.0 4.4e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.11 KFM13352.1 - 9.1e-12 44.5 0.1 9.1e-12 44.5 0.1 2.1 3 0 0 3 3 3 1 Ion channel PAS PF00989.19 KFM13352.1 - 6.3e-08 32.3 0.0 2.9e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.6 KFM13352.1 - 0.00031 20.7 0.0 0.00064 19.7 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 KFM13352.1 - 0.00034 20.6 0.0 0.012 15.6 0.0 2.8 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.1 KFM13352.1 - 0.00061 19.5 0.0 0.002 17.9 0.0 1.9 1 0 0 1 1 1 1 PAS domain Ion_trans_N PF08412.5 KFM13352.1 - 0.0047 16.1 0.2 0.014 14.7 0.2 1.8 1 0 0 1 1 1 1 Ion transport protein N-terminal PAN_3 PF08277.7 KFM13352.1 - 4 7.1 6.2 1.5 8.5 1.1 2.6 3 0 0 3 3 3 0 PAN-like domain WD40 PF00400.27 KFM13353.1 - 2.5e-17 61.9 8.9 5.4e-06 26.0 1.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat Pkinase PF00069.20 KFM13354.1 - 1.6e-67 227.4 0.0 2.3e-67 226.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM13354.1 - 4e-42 144.0 0.0 5.9e-42 143.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PB1 PF00564.19 KFM13354.1 - 2e-11 43.3 0.1 4.9e-11 42.1 0.1 1.7 1 0 0 1 1 1 1 PB1 domain Kinase-like PF14531.1 KFM13354.1 - 5.8e-06 25.4 0.0 0.00019 20.4 0.0 2.4 1 1 1 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 KFM13354.1 - 0.024 13.4 0.1 1.6 7.4 0.0 2.1 2 0 0 2 2 2 0 Seadornavirus VP7 DUF2340 PF10209.4 KFM13354.1 - 0.034 14.3 0.1 0.061 13.4 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2340) LIM PF00412.17 KFM13355.1 - 5.1e-12 45.6 10.6 7e-12 45.2 7.4 1.2 1 0 0 1 1 1 1 LIM domain DZR PF12773.2 KFM13355.1 - 0.052 13.3 3.9 2.7 7.8 0.0 2.3 2 0 0 2 2 2 0 Double zinc ribbon zf-C3HC4_2 PF13923.1 KFM13356.1 - 2.1e-09 37.2 12.0 4.4e-09 36.2 8.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFM13356.1 - 5.5e-09 35.5 9.4 1.1e-08 34.6 6.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 KFM13356.1 - 6.6e-09 35.2 2.3 6.6e-09 35.2 1.6 2.3 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_2 PF13639.1 KFM13356.1 - 2.3e-07 30.5 10.4 4.1e-07 29.7 7.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KFM13356.1 - 3.2e-06 26.6 11.5 7.5e-06 25.5 8.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM13356.1 - 4.5e-06 26.2 12.9 9.5e-06 25.2 9.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KFM13356.1 - 0.00087 18.9 3.3 0.003 17.2 2.4 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KFM13356.1 - 0.0017 18.1 9.5 0.0017 18.1 6.6 1.8 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 KFM13356.1 - 0.0031 16.9 5.4 0.0074 15.7 3.8 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-P11 PF03854.9 KFM13356.1 - 0.046 13.1 7.9 0.085 12.3 5.5 1.4 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_6 PF14835.1 KFM13356.1 - 0.21 11.4 2.8 0.4 10.4 1.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 KFM13356.1 - 0.72 10.0 11.3 0.38 10.8 5.8 2.1 2 1 0 2 2 2 0 RING-H2 zinc finger Pkinase PF00069.20 KFM13357.1 - 2e-33 115.6 0.0 3.3e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM13357.1 - 2.8e-23 82.3 0.0 4.6e-22 78.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM13357.1 - 0.18 10.7 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF1682 PF07946.9 KFM13358.1 - 1.3e-105 352.8 7.8 1.9e-105 352.3 5.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) 7tm_2 PF00002.19 KFM13359.1 - 1.4e-82 276.4 14.7 1.7e-82 276.2 10.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 KFM13359.1 - 1.5e-15 56.9 3.1 2.9e-15 56.0 2.2 1.4 1 0 0 1 1 1 1 Hormone receptor domain EF-hand_6 PF13405.1 KFM13360.1 - 7.3e-10 37.9 0.0 0.00053 19.6 0.0 4.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 KFM13360.1 - 4.5e-07 29.8 0.1 1.1e-05 25.4 0.1 2.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KFM13360.1 - 0.00011 21.1 5.8 0.12 11.6 0.0 4.4 5 1 1 6 6 6 3 EF hand EF-hand_9 PF14658.1 KFM13360.1 - 0.0023 17.8 0.0 0.99 9.3 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 KFM13360.1 - 0.56 9.8 5.3 3.1 7.4 0.0 3.3 2 1 1 3 3 3 0 EF-hand domain pair TPR_1 PF00515.23 KFM13361.1 - 1.6e-41 138.2 13.5 1e-09 37.5 0.2 8.4 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.1 KFM13361.1 - 3.5e-34 116.2 16.1 1.8e-13 49.9 0.8 6.7 4 1 1 6 6 6 4 TPR repeat TPR_2 PF07719.12 KFM13361.1 - 6e-32 106.9 14.1 6.5e-06 25.6 0.1 8.6 8 0 0 8 8 8 6 Tetratricopeptide repeat Apc3 PF12895.2 KFM13361.1 - 5.7e-30 103.2 25.0 4.9e-21 74.6 3.6 5.4 3 1 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KFM13361.1 - 2.1e-25 88.4 11.0 5.7e-08 32.5 0.0 7.1 6 1 2 8 8 7 5 Tetratricopeptide repeat TPR_16 PF13432.1 KFM13361.1 - 2.6e-23 82.1 1.7 8.8e-09 35.8 0.0 6.2 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFM13361.1 - 3.3e-22 76.7 9.8 0.00062 19.7 0.0 8.6 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 KFM13361.1 - 2.7e-21 73.6 5.2 6e-06 25.6 0.2 8.3 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 KFM13361.1 - 8e-19 67.7 4.9 0.0003 21.0 0.0 7.4 4 2 4 9 9 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 KFM13361.1 - 3.6e-16 58.1 0.0 0.069 13.8 0.0 8.3 4 1 4 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.1 KFM13361.1 - 1.4e-13 50.2 8.1 0.015 15.7 0.0 7.5 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFM13361.1 - 3.9e-09 35.6 1.1 0.23 11.3 0.0 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFM13361.1 - 3.9e-08 33.0 0.0 0.0023 17.7 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat ChAPs PF09295.5 KFM13361.1 - 0.00045 19.1 0.1 0.002 16.9 0.0 1.9 1 1 1 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_15 PF13429.1 KFM13361.1 - 0.0021 17.1 0.1 1.1 8.2 0.0 3.7 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 KFM13361.1 - 0.0049 16.7 0.3 19 5.3 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.1 KFM13361.1 - 0.014 15.5 0.7 0.22 11.6 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.4 KFM13361.1 - 0.13 12.2 0.2 1.8 8.4 0.1 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat PPTA PF01239.17 KFM13361.1 - 0.14 11.5 1.5 2.1 7.8 0.1 2.7 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat PEHE PF15275.1 KFM13362.1 - 1.8e-11 44.5 0.0 1.8e-11 44.5 0.0 3.4 3 0 0 3 3 3 1 PEHE domain Tubulin-binding PF00418.14 KFM13363.1 - 4.1e-65 215.0 26.9 6.4e-17 60.9 1.3 4.9 4 0 0 4 4 4 4 Tau and MAP protein, tubulin-binding repeat Mito_carr PF00153.22 KFM13364.1 - 2.3e-53 177.8 0.1 6.4e-21 73.8 0.0 4.6 4 1 0 4 4 4 3 Mitochondrial carrier protein RIIa PF02197.12 KFM13364.1 - 0.063 12.7 0.8 0.14 11.6 0.5 1.6 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit HCO3_cotransp PF00955.16 KFM13365.1 - 3.7e-135 451.4 12.4 4.4e-135 451.2 8.6 1.0 1 0 0 1 1 1 1 HCO3- transporter family V-set PF07686.12 KFM13366.1 - 5.7e-06 26.2 0.8 9.3e-06 25.5 0.6 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 KFM13366.1 - 5.3e-05 23.2 0.9 0.00011 22.2 0.3 1.7 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.1 KFM13366.1 - 0.00075 19.5 0.5 0.0011 19.0 0.4 1.2 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 KFM13366.1 - 0.0075 16.1 0.3 0.014 15.2 0.2 1.6 1 1 0 1 1 1 1 Immunoglobulin I-set domain NEAT PF05031.7 KFM13366.1 - 0.0081 16.1 0.1 0.018 15.0 0.0 1.5 2 0 0 2 2 2 1 Iron Transport-associated domain Herpes_gE PF02480.11 KFM13366.1 - 0.033 12.4 0.6 0.039 12.2 0.4 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E RPA_C PF08784.6 KFM13366.1 - 0.051 13.9 0.0 0.076 13.4 0.0 1.3 1 0 0 1 1 1 0 Replication protein A C terminal CUB PF00431.15 KFM13367.1 - 5.1e-25 87.6 0.0 8e-25 87.0 0.0 1.3 1 0 0 1 1 1 1 CUB domain Fz PF01392.17 KFM13367.1 - 1.4e-20 73.8 1.7 1.4e-20 73.8 1.2 1.7 2 0 0 2 2 2 1 Fz domain Ldl_recept_a PF00057.13 KFM13367.1 - 8.5e-09 35.1 8.9 8.5e-09 35.1 6.2 2.2 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A C1q PF00386.16 KFM13368.1 - 7.4e-36 122.9 0.0 9e-36 122.6 0.0 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 KFM13368.1 - 2.8e-10 39.5 32.7 6.9e-08 31.9 22.7 2.2 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Brevenin PF03032.10 KFM13368.1 - 0.035 13.9 0.6 0.053 13.3 0.4 1.3 1 0 0 1 1 1 0 Brevenin/esculentin/gaegurin/rugosin family zf-C3HC4_3 PF13920.1 KFM13370.1 - 7.1e-14 51.2 11.4 1.4e-13 50.2 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM13370.1 - 1.1e-06 28.3 12.7 2.1e-06 27.4 8.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFM13370.1 - 1.9e-06 27.7 12.5 3.7e-06 26.8 8.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM13370.1 - 0.0066 16.1 11.3 0.014 15.0 7.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KFM13370.1 - 0.3 10.9 5.6 0.72 9.7 3.9 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Pox_P35 PF03213.9 KFM13370.1 - 0.46 9.4 6.8 0.78 8.6 4.7 1.2 1 0 0 1 1 1 0 Poxvirus P35 protein Prok-RING_4 PF14447.1 KFM13370.1 - 5.8 6.5 8.8 22 4.6 6.1 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 C2-set_2 PF08205.7 KFM13371.1 - 3e-25 87.9 0.5 1.7e-20 72.7 0.2 3.9 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.1 KFM13371.1 - 8.6e-22 77.0 0.5 6.7e-09 35.7 0.0 4.2 4 1 0 4 4 4 3 Immunoglobulin domain I-set PF07679.11 KFM13371.1 - 5.9e-18 64.5 0.3 6.7e-07 29.0 0.0 4.2 3 2 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.1 KFM13371.1 - 1.6e-16 60.5 3.7 6.1e-05 23.4 0.0 4.1 4 1 0 4 4 4 3 Immunoglobulin domain ig PF00047.20 KFM13371.1 - 1.3e-08 34.8 2.5 7.9e-05 22.7 0.0 4.2 4 1 0 4 4 4 2 Immunoglobulin domain V-set PF07686.12 KFM13371.1 - 5.6e-07 29.4 2.2 0.0093 15.8 0.0 4.9 4 2 0 4 4 4 1 Immunoglobulin V-set domain Cbl_N PF02262.11 KFM13372.1 - 3.5e-62 207.8 0.2 6.1e-62 207.0 0.2 1.4 1 0 0 1 1 1 1 CBL proto-oncogene N-terminal domain 1 Cbl_N3 PF02762.9 KFM13372.1 - 2.4e-53 177.6 0.0 5.8e-53 176.4 0.0 1.7 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, SH2-like domain Cbl_N2 PF02761.9 KFM13372.1 - 9.1e-46 153.8 0.7 1.6e-45 153.0 0.5 1.4 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain zf-C3HC4_3 PF13920.1 KFM13372.1 - 5.7e-10 38.7 8.0 9.5e-10 38.0 5.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM13372.1 - 6.5e-09 35.2 7.9 1.6e-08 34.0 5.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM13372.1 - 2.9e-08 33.5 7.7 6.1e-08 32.5 5.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UBA PF00627.26 KFM13372.1 - 6.3e-06 25.8 0.0 1.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain zf-RING_2 PF13639.1 KFM13372.1 - 2e-05 24.3 6.9 2e-05 24.3 4.8 2.0 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.1 KFM13372.1 - 8e-05 22.1 4.9 0.00016 21.1 3.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.1 KFM13372.1 - 0.00021 20.9 10.5 0.00041 20.0 7.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 KFM13372.1 - 0.016 14.7 9.6 0.036 13.6 6.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 KFM13372.1 - 0.092 12.6 11.4 0.061 13.2 5.9 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KFM13372.1 - 1.4 8.7 7.3 4 7.2 5.0 1.9 1 0 0 1 1 1 0 RING-type zinc-finger Cep57_CLD_2 PF14197.1 KFM13373.1 - 4.7e-05 23.2 15.8 0.0044 16.9 4.1 3.1 2 1 1 3 3 3 2 Centrosome localisation domain of PPC89 Leu_zip PF15294.1 KFM13373.1 - 0.00011 21.3 13.3 0.00014 21.0 9.2 1.1 1 0 0 1 1 1 1 Leucine zipper NYD-SP28 PF14772.1 KFM13373.1 - 0.0031 17.5 13.9 0.0069 16.4 9.7 1.7 1 1 0 1 1 1 1 Sperm tail TMCO5 PF14992.1 KFM13373.1 - 0.0056 15.8 9.5 0.0066 15.6 6.6 1.1 1 0 0 1 1 1 1 TMCO5 family Fmp27_WPPW PF10359.4 KFM13373.1 - 0.012 14.0 8.0 0.013 13.9 5.5 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Baculo_PEP_C PF04513.7 KFM13373.1 - 0.015 15.1 3.2 0.042 13.6 2.2 1.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sec8_exocyst PF04048.9 KFM13373.1 - 0.015 14.8 2.9 0.021 14.4 2.0 1.3 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain IFT57 PF10498.4 KFM13373.1 - 0.027 13.2 9.0 0.028 13.1 6.2 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Fib_alpha PF08702.5 KFM13373.1 - 0.027 14.6 10.8 0.049 13.7 7.2 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family IL2 PF00715.12 KFM13373.1 - 0.029 14.0 1.1 0.038 13.7 0.8 1.2 1 0 0 1 1 1 0 Interleukin 2 DUF3584 PF12128.3 KFM13373.1 - 0.03 11.6 17.7 0.035 11.4 12.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) V_ATPase_I PF01496.14 KFM13373.1 - 0.033 12.0 6.7 0.039 11.8 4.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GAS PF13851.1 KFM13373.1 - 0.039 13.1 14.3 0.11 11.6 10.0 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding CALCOCO1 PF07888.6 KFM13373.1 - 0.04 12.1 13.8 0.048 11.9 9.6 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2052 PF09747.4 KFM13373.1 - 0.046 13.6 7.0 0.055 13.4 4.8 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF948 PF06103.6 KFM13373.1 - 0.048 13.5 3.4 2.5 8.0 0.0 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Bacillus_HBL PF05791.6 KFM13373.1 - 0.058 12.7 6.5 0.085 12.2 4.5 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF4164 PF13747.1 KFM13373.1 - 0.075 13.1 14.8 0.28 11.3 4.5 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Reo_sigmaC PF04582.7 KFM13373.1 - 0.082 12.0 1.9 0.13 11.4 0.9 1.4 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DUF4594 PF15266.1 KFM13373.1 - 0.088 12.9 6.3 0.13 12.4 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4594) Allexi_40kDa PF05549.6 KFM13373.1 - 0.097 11.9 1.6 0.12 11.7 1.1 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein ERM PF00769.14 KFM13373.1 - 0.1 12.1 20.8 0.14 11.6 14.4 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family MitMem_reg PF13012.1 KFM13373.1 - 0.11 12.5 4.5 0.26 11.4 2.5 1.9 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function CENP-F_leu_zip PF10473.4 KFM13373.1 - 0.12 12.2 16.6 0.17 11.7 2.6 2.8 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF87 PF01935.12 KFM13373.1 - 0.14 11.9 4.3 0.17 11.6 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF87 TMPIT PF07851.8 KFM13373.1 - 0.14 11.1 4.2 0.16 10.9 2.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein LXG PF04740.7 KFM13373.1 - 0.17 11.6 8.5 0.23 11.2 5.7 1.5 1 1 0 1 1 1 0 LXG domain of WXG superfamily DUF4055 PF13264.1 KFM13373.1 - 0.17 11.9 8.9 0.25 11.4 5.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4055) OmpH PF03938.9 KFM13373.1 - 0.18 11.6 16.8 0.24 11.3 11.6 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Spc7 PF08317.6 KFM13373.1 - 0.21 10.2 9.7 0.24 10.0 6.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Raptor_N PF14538.1 KFM13373.1 - 0.22 11.3 3.5 0.36 10.6 2.5 1.4 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain Prominin PF05478.6 KFM13373.1 - 0.25 8.8 2.5 0.25 8.8 1.8 1.1 1 0 0 1 1 1 0 Prominin Exonuc_VII_L PF02601.10 KFM13373.1 - 0.27 10.3 8.5 0.3 10.2 5.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit CR6_interact PF10147.4 KFM13373.1 - 0.27 10.5 11.7 0.52 9.5 8.1 1.4 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF342 PF03961.8 KFM13373.1 - 0.34 9.2 5.4 0.41 9.0 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Phage_GP20 PF06810.6 KFM13373.1 - 0.59 9.5 15.6 1.3 8.4 5.4 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF3086 PF11285.3 KFM13373.1 - 0.63 8.7 8.0 1.1 8.0 5.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3086) DUF2203 PF09969.4 KFM13373.1 - 0.66 10.2 9.2 15 5.8 6.4 2.2 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Lys-AminoMut_A PF09043.6 KFM13373.1 - 0.73 7.8 3.5 1 7.4 2.4 1.2 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase alpha subunit Jnk-SapK_ap_N PF09744.4 KFM13373.1 - 0.77 9.7 11.6 1.2 9.0 8.1 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Apolipoprotein PF01442.13 KFM13373.1 - 0.86 9.0 19.8 1.8 8.0 13.7 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain FUSC PF04632.7 KFM13373.1 - 0.88 7.9 8.4 0.95 7.8 5.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4200 PF13863.1 KFM13373.1 - 0.9 9.4 16.8 1.4 8.8 11.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) APG6 PF04111.7 KFM13373.1 - 0.93 8.4 11.6 1.2 8.1 8.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Striatin PF08232.7 KFM13373.1 - 0.96 9.7 13.8 2.2 8.5 9.5 1.8 1 1 0 1 1 1 0 Striatin family IncA PF04156.9 KFM13373.1 - 1.1 8.8 19.5 4.2 6.9 5.0 2.1 1 1 1 2 2 2 0 IncA protein Atg14 PF10186.4 KFM13373.1 - 1.2 8.0 15.5 1.8 7.4 10.8 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SRA1 PF07304.6 KFM13373.1 - 1.4 8.6 5.6 1.1 8.9 2.6 1.6 1 1 0 1 1 1 0 Steroid receptor RNA activator (SRA1) HAUS-augmin3 PF14932.1 KFM13373.1 - 1.6 7.8 17.0 8.8 5.4 10.6 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 TMF_DNA_bd PF12329.3 KFM13373.1 - 2.1 8.2 16.0 27 4.6 6.2 3.1 1 1 2 3 3 2 0 TATA element modulatory factor 1 DNA binding DUF3708 PF12501.3 KFM13373.1 - 2.2 8.1 6.3 3.8 7.3 4.0 1.7 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter AAA_32 PF13654.1 KFM13373.1 - 2.2 6.8 12.8 0.72 8.4 6.2 1.7 1 1 1 2 2 2 0 AAA domain NPV_P10 PF05531.7 KFM13373.1 - 2.3 8.5 5.8 4.1 7.7 1.0 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 KFM13373.1 - 2.6 7.8 6.7 9.9 5.9 4.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) AAA_13 PF13166.1 KFM13373.1 - 2.9 6.2 10.6 4.5 5.6 6.8 1.4 1 1 0 1 1 1 0 AAA domain ADIP PF11559.3 KFM13373.1 - 3.3 7.5 19.9 7.2 6.4 13.3 1.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding CorA PF01544.13 KFM13373.1 - 3.4 6.6 7.5 3.7 6.5 4.5 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Prefoldin PF02996.12 KFM13373.1 - 3.7 7.2 14.7 0.38 10.4 1.7 2.7 1 1 1 2 2 2 0 Prefoldin subunit FlgN PF05130.7 KFM13373.1 - 4.2 7.6 19.6 8.1 6.6 12.4 1.9 1 1 1 2 2 2 0 FlgN protein ACCA PF03255.9 KFM13373.1 - 5.3 6.5 7.7 15 5.1 5.1 1.9 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF2383 PF09537.5 KFM13373.1 - 5.5 7.2 10.9 4.1 7.6 2.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF2383) SlyX PF04102.7 KFM13373.1 - 5.5 7.4 16.3 1.1 9.6 2.9 2.8 1 1 2 3 3 3 0 SlyX DUF4446 PF14584.1 KFM13373.1 - 5.8 6.7 9.0 10 5.9 4.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) DUF2951 PF11166.3 KFM13373.1 - 6 6.7 8.1 1.4 8.7 2.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) DUF1690 PF07956.6 KFM13373.1 - 6.4 6.7 13.1 10 6.1 9.1 1.5 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) HXXSHH PF07586.6 KFM13373.1 - 7.4 5.3 10.4 9.5 5.0 7.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1552) Syntaxin PF00804.20 KFM13373.1 - 7.5 6.7 12.3 6.3 7.0 6.0 2.1 1 1 1 2 2 2 0 Syntaxin GrpE PF01025.14 KFM13373.1 - 9.3 5.7 15.2 50 3.3 9.6 2.1 1 1 1 2 2 2 0 GrpE Pox_A_type_inc PF04508.7 KFM13373.1 - 9.4 6.3 6.5 15 5.6 0.4 3.3 3 0 0 3 3 2 0 Viral A-type inclusion protein repeat Phage_GPO PF05929.6 KFM13373.1 - 9.8 5.3 12.4 19 4.3 8.6 1.5 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase LRR_6 PF13516.1 KFM13374.1 - 1.7e-09 36.7 11.4 0.09 12.8 0.0 7.3 7 0 0 7 7 7 3 Leucine Rich repeat NACHT PF05729.7 KFM13374.1 - 2.1e-08 33.9 0.0 8.5e-08 32.0 0.0 2.1 1 0 0 1 1 1 1 NACHT domain LRR_4 PF12799.2 KFM13374.1 - 0.00085 18.8 6.0 0.015 14.8 0.2 4.8 4 1 1 5 5 5 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM13374.1 - 0.96 9.2 12.9 0.22 11.3 1.2 4.1 4 2 0 4 4 4 0 Leucine rich repeat ABC2_membrane PF01061.19 KFM13375.1 - 3.3e-45 153.8 23.4 5e-45 153.2 16.3 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 KFM13375.1 - 4.3e-26 91.8 0.0 6.8e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KFM13375.1 - 2.6e-11 44.0 0.0 8.7e-06 25.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KFM13375.1 - 2.6e-06 26.8 0.3 0.00042 19.5 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 KFM13375.1 - 0.00024 20.3 0.0 0.00041 19.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC2_membrane_3 PF12698.2 KFM13375.1 - 0.00028 20.0 21.9 0.00032 19.8 14.4 1.6 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_17 PF13207.1 KFM13375.1 - 0.0016 19.2 0.0 0.0034 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KFM13375.1 - 0.025 14.0 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ArgK PF03308.11 KFM13375.1 - 0.027 13.2 0.1 0.042 12.6 0.0 1.2 1 0 0 1 1 1 0 ArgK protein AAA_10 PF12846.2 KFM13375.1 - 0.031 13.7 0.1 0.056 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain MMR_HSR1 PF01926.18 KFM13375.1 - 0.035 14.0 0.1 0.075 12.9 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.1 KFM13375.1 - 0.079 13.2 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KFM13375.1 - 0.083 12.8 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_13 PF13166.1 KFM13375.1 - 0.15 10.5 0.0 2.5 6.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 KFM13375.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.10 KFM13375.1 - 0.15 10.6 0.1 0.22 10.1 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_23 PF13476.1 KFM13375.1 - 0.19 12.0 0.1 0.38 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain zf-H2C2_2 PF13465.1 KFM13376.1 - 3.6e-16 58.5 72.1 1.1e-06 28.6 3.0 10.0 12 1 0 12 12 12 6 Zinc-finger double domain zf-C2H2 PF00096.21 KFM13376.1 - 8.3e-15 54.1 87.1 5.4e-05 23.2 3.9 10.2 10 2 0 10 10 10 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM13376.1 - 1.1e-11 44.1 81.7 0.00054 20.1 2.5 10.5 10 0 0 10 10 10 7 C2H2-type zinc finger zf-met PF12874.2 KFM13376.1 - 0.00012 22.1 34.2 0.18 12.0 0.0 7.0 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-Di19 PF05605.7 KFM13376.1 - 0.0032 17.5 6.3 0.0032 17.5 4.4 7.5 6 1 1 7 7 7 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 KFM13376.1 - 0.0033 17.5 47.8 0.006 16.6 0.5 7.4 9 0 0 9 9 9 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFM13376.1 - 0.0059 16.4 1.5 0.0059 16.4 1.0 7.8 8 0 0 8 8 8 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KFM13376.1 - 0.025 14.2 0.8 0.025 14.2 0.6 5.7 7 0 0 7 7 7 0 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.1 KFM13376.1 - 0.08 13.2 64.0 0.083 13.1 1.2 8.8 9 0 0 9 9 9 0 C2H2-type zinc-finger domain Oest_recep PF02159.10 KFM13378.1 - 2 8.5 9.1 2.6 8.1 6.1 1.5 1 1 0 1 1 1 0 Oestrogen receptor PD-C2-AF1 PF09310.5 KFM13379.1 - 1.1e-140 467.0 18.2 1.2e-140 466.9 12.6 1.0 1 0 0 1 1 1 1 POU domain, class 2, associating factor 1 BTG PF07742.7 KFM13380.1 - 2.2e-45 153.0 0.1 3e-45 152.5 0.0 1.2 1 0 0 1 1 1 1 BTG family Malate_DH PF12434.3 KFM13380.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Malate dehydrogenase enzyme Pkinase PF00069.20 KFM13381.1 - 4.4e-70 235.8 0.0 7.4e-70 235.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM13381.1 - 2.2e-36 125.2 0.0 3.5e-36 124.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM13381.1 - 3.7e-08 32.6 0.0 7.4e-08 31.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFM13381.1 - 0.015 14.3 0.1 0.032 13.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_transf_22 PF03901.12 KFM13382.1 - 7.4e-122 407.3 32.5 8.6e-122 407.1 22.5 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Sigma_reg_N PF13800.1 KFM13382.1 - 0.51 10.4 2.8 2.2 8.3 0.2 2.7 2 0 0 2 2 2 0 Sigma factor regulator N-terminal GPP34 PF05719.6 KFM13383.1 - 1.8e-49 168.6 1.3 2.1e-49 168.3 0.9 1.0 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Endosulfine PF04667.12 KFM13384.1 - 9.7e-16 57.5 0.9 1.1e-15 57.4 0.6 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region MAS20 PF02064.10 KFM13384.1 - 0.072 12.9 0.0 0.072 12.9 0.0 1.1 1 0 0 1 1 1 0 MAS20 protein import receptor Bcl-2 PF00452.14 KFM13385.1 - 2.3e-21 75.7 0.3 3e-21 75.4 0.2 1.1 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family BALF1 PF06861.6 KFM13385.1 - 0.019 14.3 0.0 0.025 14.0 0.0 1.1 1 0 0 1 1 1 0 BALF1 protein MENTAL PF10457.4 KFM13386.1 - 3.1e-74 248.2 10.4 3.5e-74 248.0 7.2 1.0 1 0 0 1 1 1 1 Cholesterol-capturing domain zf-C4H2 PF10146.4 KFM13387.1 - 2.4e-84 282.9 21.6 2.7e-84 282.7 15.0 1.0 1 0 0 1 1 1 1 Zinc finger-containing protein Sec20 PF03908.8 KFM13387.1 - 0.0048 16.5 0.6 0.011 15.3 0.1 1.8 1 1 0 1 1 1 1 Sec20 DZR PF12773.2 KFM13387.1 - 0.011 15.5 1.5 0.02 14.7 1.0 1.4 1 0 0 1 1 1 0 Double zinc ribbon BLOC1_2 PF10046.4 KFM13387.1 - 0.026 14.6 6.7 1.3 9.1 0.2 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-P11 PF03854.9 KFM13387.1 - 0.07 12.6 2.3 0.13 11.7 1.6 1.4 1 0 0 1 1 1 0 P-11 zinc finger zf-C3HC4_3 PF13920.1 KFM13387.1 - 0.088 12.4 4.2 0.15 11.7 2.9 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KFM13387.1 - 0.099 12.2 2.8 0.19 11.3 1.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PA28_alpha PF02251.13 KFM13387.1 - 0.11 12.6 0.4 0.35 11.0 0.3 1.9 1 0 0 1 1 1 0 Proteasome activator pa28 alpha subunit Lipoprotein_7 PF01540.11 KFM13387.1 - 0.13 11.2 2.8 0.21 10.6 2.0 1.3 1 0 0 1 1 1 0 Adhesin lipoprotein Polysacc_synt_4 PF04669.8 KFM13387.1 - 0.19 11.1 2.3 0.32 10.3 1.6 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis DUF4041 PF13250.1 KFM13387.1 - 0.2 11.2 1.5 0.49 9.9 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) Tup_N PF08581.5 KFM13387.1 - 0.29 11.3 8.2 1 9.6 5.7 2.0 1 1 0 1 1 1 0 Tup N-terminal DUF1664 PF07889.7 KFM13387.1 - 0.37 10.5 4.0 0.62 9.8 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Spc7 PF08317.6 KFM13387.1 - 0.48 9.0 10.5 0.61 8.6 7.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Baculo_IE-1 PF05290.6 KFM13387.1 - 0.9 9.2 4.3 5.2 6.7 0.3 2.5 2 1 1 3 3 3 0 Baculovirus immediate-early protein (IE-0) TMF_TATA_bd PF12325.3 KFM13387.1 - 2.2 8.0 18.0 3.3 7.4 1.7 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.4 KFM13387.1 - 2.4 8.0 18.9 5.5 6.8 13.1 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WAC_Acf1_DNA_bd PF10537.4 KFM13387.1 - 2.5 8.3 5.5 5.2 7.2 0.8 2.3 1 1 0 2 2 2 0 ATP-utilising chromatin assembly and remodelling N-terminal DUF3450 PF11932.3 KFM13387.1 - 2.7 7.2 16.6 0.27 10.4 2.3 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF3450) HALZ PF02183.13 KFM13387.1 - 3.4 7.4 15.3 2.3 7.9 2.6 2.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper V_ATPase_I PF01496.14 KFM13387.1 - 3.4 5.3 6.8 4.6 4.9 4.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Occludin_ELL PF07303.8 KFM13387.1 - 6.5 7.5 9.7 8 7.2 2.9 2.7 1 1 2 3 3 3 0 Occludin homology domain RNase_Zc3h12a PF11977.3 KFM13388.1 - 6.5e-64 214.4 0.0 9.1e-64 213.9 0.0 1.2 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain zf-CCCH_2 PF14608.1 KFM13388.1 - 0.63 10.1 10.0 1.1 9.3 6.9 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Omega-toxin PF06357.6 KFM13388.1 - 0.74 9.4 7.8 0.069 12.7 2.1 1.7 2 0 0 2 2 2 0 Omega-atracotoxin zf-CCCH PF00642.19 KFM13388.1 - 1 9.1 7.7 2.5 7.8 3.9 2.2 1 1 1 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF2890 PF11081.3 KFM13389.1 - 0.18 11.8 2.3 0.24 11.4 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Las1 PF04031.8 KFM13390.1 - 5.7e-35 120.2 0.0 7e-35 119.9 0.0 1.1 1 0 0 1 1 1 1 Las1-like ERM PF00769.14 KFM13391.1 - 1.7e-72 243.8 70.7 1.7e-72 243.8 49.0 2.3 1 1 1 2 2 2 1 Ezrin/radixin/moesin family FERM_C PF09380.5 KFM13391.1 - 4.9e-33 113.2 0.0 1.7e-32 111.4 0.0 2.0 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.13 KFM13391.1 - 6.8e-26 90.9 0.6 6.8e-26 90.9 0.4 4.1 2 1 1 3 3 3 1 FERM central domain FERM_N PF09379.5 KFM13391.1 - 5.4e-19 68.0 0.2 5.4e-19 68.0 0.1 3.3 3 0 0 3 3 3 1 FERM N-terminal domain Fer2 PF00111.22 KFM13392.1 - 4.8e-08 32.6 0.6 6.4e-08 32.2 0.4 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain RhoGAP PF00620.22 KFM13393.1 - 8.7e-36 122.8 0.1 8.4e-35 119.6 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.24 KFM13393.1 - 1.8e-07 31.3 0.6 1.4e-06 28.4 0.1 2.3 2 0 0 2 2 2 1 PH domain Ras_bdg_2 PF14847.1 KFM13393.1 - 5.5e-05 23.0 0.0 0.0002 21.2 0.0 2.0 1 0 0 1 1 1 1 Ras-binding domain of Byr2 RA PF00788.18 KFM13393.1 - 8e-05 23.0 0.0 0.0002 21.7 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain DUF2183 PF09949.4 KFM13393.1 - 0.14 12.1 0.0 0.47 10.4 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) V-set PF07686.12 KFM13394.1 - 6.3e-17 61.5 0.2 1.8e-09 37.4 0.1 3.1 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.1 KFM13394.1 - 1.3e-13 50.8 0.0 1.3e-06 28.3 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 KFM13394.1 - 3.5e-13 49.8 0.1 2.3e-07 31.2 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 KFM13394.1 - 2.2e-11 43.4 0.0 0.00017 21.3 0.0 3.0 2 1 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.20 KFM13394.1 - 3.2e-07 30.3 3.9 0.014 15.4 0.1 4.0 2 2 1 3 3 3 2 Immunoglobulin domain V-set_CD47 PF08204.6 KFM13394.1 - 0.0086 15.8 0.0 0.057 13.1 0.0 2.0 2 0 0 2 2 2 1 CD47 immunoglobulin-like domain Phage_tail_2 PF06199.6 KFM13394.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Phage major tail protein 2 V-set PF07686.12 KFM13395.1 - 1.8e-16 60.0 0.1 5.2e-09 36.0 0.0 3.1 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.1 KFM13395.1 - 7.7e-13 48.3 0.0 1.3e-06 28.3 0.0 2.3 2 1 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 KFM13395.1 - 2.2e-12 47.2 0.6 2.3e-07 31.2 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 KFM13395.1 - 2.2e-12 46.6 0.0 0.00013 21.7 0.0 2.9 2 1 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.20 KFM13395.1 - 4.2e-08 33.2 3.0 0.0017 18.4 0.0 3.5 3 1 0 3 3 3 2 Immunoglobulin domain V-set_CD47 PF08204.6 KFM13395.1 - 0.1 12.3 0.0 0.64 9.7 0.0 2.0 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain Cu-oxidase_2 PF07731.9 KFM13396.1 - 6.6e-28 96.9 11.0 1.4e-11 44.0 0.4 5.9 5 0 0 5 5 5 5 Multicopper oxidase Cu-oxidase_3 PF07732.10 KFM13396.1 - 7.9e-25 86.8 3.7 6e-08 32.4 0.0 5.5 6 1 0 6 6 6 3 Multicopper oxidase Sarcoglycan_2 PF05510.8 KFM13396.1 - 0.13 10.5 0.2 0.21 9.8 0.1 1.2 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon 7tm_1 PF00001.16 KFM13397.1 - 5.5e-59 199.3 28.1 6e-58 195.9 20.6 1.7 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM13397.1 - 2.8e-14 52.8 28.5 3.6e-14 52.5 19.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF2109 PF09882.4 KFM13397.1 - 1.7 8.6 9.0 1.2 9.1 2.5 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2109) 7tm_1 PF00001.16 KFM13398.1 - 7.4e-59 198.9 23.4 1.1e-58 198.3 16.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM13398.1 - 5.7e-16 58.4 22.3 7.3e-16 58.1 15.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF2109 PF09882.4 KFM13398.1 - 1.3 9.0 10.5 0.19 11.7 1.8 2.8 2 1 0 2 2 2 0 Predicted membrane protein (DUF2109) TNFR_c6 PF00020.13 KFM13399.1 - 2e-11 43.7 25.9 3.3e-07 30.2 1.2 3.8 3 1 2 5 5 5 2 TNFR/NGFR cysteine-rich region UPF0560 PF10577.4 KFM13399.1 - 0.2 9.8 0.3 0.27 9.4 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 NCD3G PF07562.9 KFM13399.1 - 0.21 11.3 20.7 0.51 10.0 2.5 4.1 2 1 0 3 3 3 0 Nine Cysteines Domain of family 3 GPCR GCC2_GCC3 PF07699.8 KFM13399.1 - 0.66 9.5 25.1 0.11 12.1 2.7 3.6 2 1 1 3 3 3 0 GCC2 and GCC3 Hormone_recep PF00104.25 KFM13400.1 - 1.9e-31 108.7 2.4 3.4e-31 107.9 1.7 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFM13400.1 - 1.1e-27 95.9 14.4 2.2e-27 95.0 10.0 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) RhoGAP PF00620.22 KFM13401.1 - 1.3e-40 138.5 0.1 4e-40 136.8 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain YlqD PF11068.3 KFM13401.1 - 3.8 7.5 8.9 1.5 8.8 2.8 2.3 2 0 0 2 2 2 0 YlqD protein Yip1 PF04893.12 KFM13402.1 - 3.7e-18 65.6 12.6 3.7e-18 65.6 8.8 1.7 1 1 1 2 2 2 1 Yip1 domain START PF01852.14 KFM13403.1 - 2.8e-40 137.8 0.1 5.3e-40 136.9 0.1 1.4 1 0 0 1 1 1 1 START domain RhoGAP PF00620.22 KFM13403.1 - 3.2e-39 133.9 0.2 6.2e-39 133.0 0.1 1.4 1 0 0 1 1 1 1 RhoGAP domain SAM_2 PF07647.12 KFM13403.1 - 0.0058 16.4 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) LRR_8 PF13855.1 KFM13404.1 - 1.2e-45 153.0 23.7 1.5e-14 53.5 2.9 5.4 1 1 4 5 5 5 5 Leucine rich repeat 7tm_1 PF00001.16 KFM13404.1 - 2.8e-26 92.2 7.1 4.6e-26 91.5 4.9 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_4 PF12799.2 KFM13404.1 - 2.9e-23 81.0 28.0 7.8e-06 25.3 0.0 6.2 2 2 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFM13404.1 - 6.1e-18 64.7 0.1 4.4e-09 36.1 0.0 2.4 1 1 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_1 PF00560.28 KFM13404.1 - 3.7e-14 50.5 22.7 0.044 13.8 0.6 10.6 10 0 0 10 10 10 4 Leucine Rich Repeat Ldl_recept_a PF00057.13 KFM13404.1 - 3.9e-09 36.2 6.9 8.1e-09 35.2 4.8 1.6 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A LRR_9 PF14580.1 KFM13404.1 - 1.6e-08 34.2 1.7 0.0001 21.8 0.2 2.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_7 PF13504.1 KFM13404.1 - 5.8e-08 31.6 17.9 0.35 11.2 0.2 8.8 9 1 0 9 9 9 3 Leucine rich repeat LRR_6 PF13516.1 KFM13404.1 - 1.1e-06 28.1 8.7 13 6.1 0.0 8.1 8 1 1 9 9 9 1 Leucine Rich repeat LRRNT PF01462.13 KFM13404.1 - 4.4e-06 26.0 0.4 1.4e-05 24.3 0.3 1.9 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain Ephrin PF00812.12 KFM13405.1 - 2.7e-45 153.4 0.2 2.7e-45 153.4 0.1 1.8 2 0 0 2 2 2 1 Ephrin DUF4381 PF14316.1 KFM13405.1 - 0.002 18.2 0.0 0.003 17.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) Baculo_11_kDa PF06143.6 KFM13405.1 - 0.0091 15.3 0.7 0.016 14.5 0.5 1.3 1 0 0 1 1 1 1 Baculovirus 11 kDa family Orthoreo_P10 PF07204.6 KFM13405.1 - 0.025 14.3 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Shisa PF13908.1 KFM13405.1 - 0.027 14.6 0.0 0.045 13.9 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Protocadherin PF08374.6 KFM13405.1 - 0.033 13.8 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 Protocadherin P12 PF12669.2 KFM13405.1 - 0.071 13.3 1.8 0.082 13.1 0.1 2.0 2 0 0 2 2 2 0 Virus attachment protein p12 family Syndecan PF01034.15 KFM13405.1 - 0.076 12.6 2.3 0.13 11.9 1.6 1.3 1 0 0 1 1 1 0 Syndecan domain Cytomega_TRL10 PF06084.6 KFM13405.1 - 0.078 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein EphA2_TM PF14575.1 KFM13405.1 - 0.14 12.5 0.3 0.26 11.7 0.2 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MSC PF09402.5 KFM13405.1 - 0.14 10.8 0.2 0.22 10.1 0.1 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain WSS_VP PF12175.3 KFM13405.1 - 0.18 10.8 0.7 0.3 10.1 0.5 1.3 1 0 0 1 1 1 0 White spot syndrome virus structural envelope protein VP TMEM154 PF15102.1 KFM13405.1 - 0.18 11.5 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family SKG6 PF08693.5 KFM13405.1 - 0.26 10.6 2.4 0.46 9.8 1.7 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain ATP-grasp_4 PF13535.1 KFM13406.1 - 0.071 12.8 0.1 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain Mid1 PF12929.2 KFM13406.1 - 0.14 10.8 15.3 0.018 13.7 3.9 2.2 1 1 1 2 2 2 0 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 KFM13406.1 - 2.6 8.4 13.7 3.2 8.1 8.8 1.7 1 1 0 1 1 1 0 Fz domain TNF PF00229.13 KFM13407.1 - 1.3e-17 63.5 0.1 1.8e-17 63.0 0.1 1.2 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family Collagen PF01391.13 KFM13407.1 - 4.8e-06 26.0 45.4 0.0061 16.0 31.5 2.7 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) LRR_8 PF13855.1 KFM13408.1 - 1.9e-59 197.2 52.2 7.8e-13 47.9 0.5 9.6 6 2 4 10 10 10 10 Leucine rich repeat LRR_4 PF12799.2 KFM13408.1 - 5.1e-50 166.3 54.3 5.9e-07 28.9 0.0 11.7 9 2 2 11 11 11 11 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM13408.1 - 5.5e-35 113.9 54.7 0.02 14.8 0.3 18.9 20 0 0 20 20 20 14 Leucine Rich Repeat LRR_6 PF13516.1 KFM13408.1 - 1.3e-15 55.6 64.7 1.3 9.3 0.0 18.1 16 3 2 18 18 18 7 Leucine Rich repeat LRR_7 PF13504.1 KFM13408.1 - 1.3e-13 48.6 66.2 0.78 10.2 0.0 18.7 20 0 0 20 20 20 6 Leucine rich repeat LRR_5 PF13306.1 KFM13408.1 - 2e-05 24.2 0.0 0.15 11.7 0.0 3.4 4 0 0 4 4 4 2 Leucine rich repeats (6 copies) LRR_9 PF14580.1 KFM13408.1 - 0.00012 21.6 3.6 0.026 14.0 0.1 4.8 4 2 1 5 5 5 1 Leucine-rich repeat LRRNT PF01462.13 KFM13408.1 - 0.032 13.7 0.2 0.13 11.7 0.1 2.1 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain FNIP PF05725.7 KFM13408.1 - 0.28 11.1 3.1 18 5.3 0.1 3.9 4 0 0 4 4 4 0 FNIP Repeat wnt PF00110.14 KFM13409.1 - 1e-108 363.2 13.1 1.2e-108 363.0 9.1 1.0 1 0 0 1 1 1 1 wnt family DUF4644 PF15486.1 KFM13409.1 - 0.088 12.7 2.3 0.23 11.4 1.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4644) TAP42 PF04177.7 KFM13410.1 - 1.4e-74 251.1 0.3 3.6e-74 249.7 0.2 1.6 1 1 0 1 1 1 1 TAP42-like family Ribosomal_60s PF00428.14 KFM13410.1 - 0.16 12.3 2.4 0.85 10.0 0.2 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein DAGAT PF03982.8 KFM13411.1 - 1.2e-118 395.1 0.0 1.5e-118 394.8 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DUF2852 PF11014.3 KFM13411.1 - 6.4 6.7 5.9 17 5.3 4.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2852) 7tm_1 PF00001.16 KFM13412.1 - 1.5e-49 168.4 28.0 1.7e-49 168.2 19.4 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Serpentine_r_xa PF03383.10 KFM13412.1 - 0.011 15.4 5.4 0.011 15.4 3.7 2.3 1 1 1 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa COX7C PF02935.11 KFM13412.1 - 0.058 13.2 2.1 4.8 7.0 0.1 2.7 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc DUF508 PF04370.7 KFM13412.1 - 0.14 11.7 0.7 0.24 11.0 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF508) DUF1980 PF09323.5 KFM13412.1 - 0.16 11.7 4.9 0.28 10.9 0.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1980) Cytochrom_NNT PF03264.9 KFM13412.1 - 1.1 8.6 3.0 0.88 8.9 0.2 2.1 2 1 0 2 2 2 0 NapC/NirT cytochrome c family, N-terminal region Sigma_reg_N PF13800.1 KFM13412.1 - 4.5 7.3 13.1 0.16 11.9 0.9 3.6 4 0 0 4 4 4 0 Sigma factor regulator N-terminal Arrestin_N PF00339.24 KFM13414.1 - 3.2e-37 127.6 0.0 7.1e-33 113.5 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KFM13414.1 - 3.4e-25 88.7 1.2 5.5e-25 88.0 0.8 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain BatD PF13584.1 KFM13414.1 - 0.0081 14.8 0.4 0.011 14.3 0.3 1.1 1 0 0 1 1 1 1 Oxygen tolerance Glyco_hydro_66 PF13199.1 KFM13414.1 - 0.037 12.4 0.4 0.047 12.0 0.3 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 CBM49 PF09478.5 KFM13414.1 - 0.17 11.9 0.8 0.31 11.1 0.5 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain CBM49 VirDNA-topo-I_N PF09266.5 KFM13414.1 - 0.38 10.6 4.5 0.53 10.2 1.7 2.3 2 0 0 2 2 2 0 Viral DNA topoisomerase I, N-terminal Ras PF00071.17 KFM13415.1 - 1.6e-55 186.9 0.4 2e-55 186.6 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM13415.1 - 1.4e-17 64.3 0.1 3.4e-17 63.0 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFM13415.1 - 1.2e-12 47.3 0.5 1.4e-12 47.1 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFM13415.1 - 2.6e-07 30.2 0.1 4.3e-07 29.5 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KFM13415.1 - 0.00091 18.4 0.1 0.0013 17.9 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 KFM13415.1 - 0.0079 15.4 0.1 0.018 14.3 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Gtr1_RagA PF04670.7 KFM13415.1 - 0.037 13.1 0.2 0.045 12.8 0.2 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PDZ PF00595.19 KFM13416.1 - 6.9e-18 64.6 0.2 7.8e-18 64.4 0.1 1.0 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM13416.1 - 2.6e-08 33.6 0.0 2.6e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 PDZ domain Kinesin PF00225.18 KFM13417.1 - 2.5e-114 381.4 0.0 2.5e-114 381.4 0.0 3.1 4 1 0 4 4 4 1 Kinesin motor domain TFIID-31kDa PF02291.10 KFM13418.1 - 1.8e-38 131.2 0.0 3e-38 130.5 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 KFM13418.1 - 0.016 15.2 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KFM13418.1 - 0.02 15.0 0.1 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 Kinetochore component CENP-S 7tm_1 PF00001.16 KFM13419.1 - 3.8e-08 32.7 15.7 4.9e-08 32.4 10.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.16 KFM13420.1 - 2.4e-54 184.1 22.9 2.4e-54 184.1 15.9 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM13420.1 - 3.2e-08 33.0 26.5 4.5e-08 32.5 18.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Serpentine_r_xa PF03383.10 KFM13420.1 - 0.019 14.7 1.9 0.019 14.7 1.3 2.7 1 1 1 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa 7TM_GPCR_Srx PF10328.4 KFM13420.1 - 0.24 10.4 33.6 1.4 8.0 23.2 2.1 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.16 KFM13421.1 - 8e-42 143.1 22.1 1.1e-41 142.6 15.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.16 KFM13422.1 - 8.5e-46 156.1 23.5 1.6e-45 155.2 16.3 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 60KD_IMP PF02096.15 KFM13422.1 - 1.1 8.8 6.7 8.9 5.9 4.7 2.1 1 1 0 1 1 1 0 60Kd inner membrane protein 7tm_1 PF00001.16 KFM13423.1 - 9.8e-46 155.9 16.8 1.1e-45 155.7 11.7 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.4 KFM13423.1 - 2.7e-05 23.4 0.8 2.7e-05 23.4 0.6 2.7 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF2975 PF11188.3 KFM13423.1 - 0.0021 17.7 1.5 0.0021 17.7 1.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF2975) BRICHOS PF04089.9 KFM13424.1 - 3.5e-28 97.2 0.0 6.9e-28 96.3 0.0 1.5 2 0 0 2 2 2 1 BRICHOS domain T-box PF00907.17 KFM13425.1 - 2.8e-14 53.0 0.4 4.2e-14 52.4 0.3 1.2 1 0 0 1 1 1 1 T-box Snf7 PF03357.16 KFM13426.1 - 4.5e-27 94.5 18.1 5e-27 94.3 12.5 1.0 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.9 KFM13426.1 - 1e-05 25.0 6.3 1.4e-05 24.5 4.4 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Mu-like_Pro PF10123.4 KFM13426.1 - 0.0041 16.6 9.3 0.0054 16.2 6.4 1.1 1 0 0 1 1 1 1 Mu-like prophage I protein GrpE PF01025.14 KFM13426.1 - 0.013 15.0 7.9 0.021 14.3 5.5 1.3 1 0 0 1 1 1 0 GrpE MAP65_ASE1 PF03999.7 KFM13426.1 - 0.014 14.0 4.5 0.019 13.6 3.1 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) HAUS5 PF14817.1 KFM13426.1 - 0.096 11.2 7.3 0.12 10.9 5.1 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 DUF948 PF06103.6 KFM13426.1 - 0.32 10.8 7.9 0.21 11.4 3.6 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Mt_ATP-synt_D PF05873.7 KFM13426.1 - 0.35 10.5 3.6 1.6 8.3 0.0 2.3 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) DUF939_C PF11728.3 KFM13426.1 - 0.52 10.0 10.7 1.7 8.4 2.6 2.2 1 1 1 2 2 2 0 DUF939 C-terminal domain Fib_alpha PF08702.5 KFM13426.1 - 1.6 8.8 8.6 1 9.4 1.2 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family HSCB_C PF07743.8 KFM13426.1 - 3.9 8.0 8.1 22 5.5 1.6 2.6 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain FlxA PF14282.1 KFM13426.1 - 9.3 6.2 12.8 1.2 9.0 2.3 2.3 1 1 1 2 2 2 0 FlxA-like protein DUF1693 PF07984.7 KFM13427.1 - 1.7e-170 566.3 3.0 2e-170 566.1 2.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1693) WD40 PF00400.27 KFM13428.1 - 6.8e-48 158.9 23.3 4.8e-08 32.5 0.1 8.9 10 0 0 10 10 10 7 WD domain, G-beta repeat Bromodomain PF00439.20 KFM13428.1 - 9.2e-37 124.8 0.4 2.7e-17 62.4 0.1 2.6 2 0 0 2 2 2 2 Bromodomain HMG14_17 PF01101.13 KFM13430.1 - 1.2e-13 51.5 38.5 4.6e-13 49.6 26.7 1.7 1 1 0 1 1 1 1 HMG14 and HMG17 Pap_E4 PF02711.9 KFM13430.1 - 6.3 7.7 10.7 14 6.5 7.4 1.7 1 1 0 1 1 1 0 E4 protein SH3BGR PF04908.10 KFM13431.1 - 3.1e-36 123.2 0.1 3.7e-36 123.0 0.0 1.1 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.19 KFM13431.1 - 0.00055 19.8 0.0 0.00082 19.3 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DUF4569 PF15133.1 KFM13432.1 - 8.3e-106 353.8 2.2 9.4e-106 353.6 1.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4569) Na_H_Exchanger PF00999.16 KFM13433.1 - 4.5e-80 269.0 35.8 5.3e-80 268.7 24.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Claudin_2 PF13903.1 KFM13434.1 - 7.9e-25 87.5 2.8 1.2e-24 86.9 2.0 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 KFM13434.1 - 0.0031 17.1 9.2 0.085 12.5 4.1 2.7 2 1 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family Pkinase PF00069.20 KFM13435.1 - 7.7e-144 477.5 0.0 4.8e-71 238.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFM13435.1 - 2.7e-74 249.5 0.0 7.9e-40 136.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KFM13435.1 - 2.3e-14 53.0 0.0 1.3e-07 30.8 0.0 3.6 3 1 0 3 3 3 2 Kinase-like Kdo PF06293.9 KFM13435.1 - 2.6e-09 36.4 0.0 0.00011 21.3 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.19 KFM13435.1 - 3.4e-06 27.4 1.0 7.6e-06 26.3 0.7 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain YrbL-PhoP_reg PF10707.4 KFM13435.1 - 8.9e-06 25.1 0.0 0.019 14.2 0.0 2.4 2 0 0 2 2 2 2 PhoP regulatory network protein YrbL APH PF01636.18 KFM13435.1 - 6.3e-05 22.8 0.4 0.18 11.5 0.0 3.2 2 2 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.17 KFM13435.1 - 0.011 15.0 0.0 0.68 9.2 0.0 2.4 2 0 0 2 2 2 0 RIO1 family Choline_kinase PF01633.15 KFM13435.1 - 0.049 13.1 0.1 4.6 6.7 0.0 2.3 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 KFM13435.1 - 0.051 12.3 0.2 0.69 8.6 0.0 2.1 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Homeobox PF00046.24 KFM13436.1 - 3.7e-11 42.4 2.0 6.3e-05 22.5 0.0 2.7 2 0 0 2 2 2 2 Homeobox domain DUF1170 PF06663.8 KFM13437.1 - 5.2e-62 209.1 1.8 1.1e-61 208.0 1.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1170) CRIC_ras_sig PF10534.4 KFM13437.1 - 7.2e-41 138.1 1.6 9.6e-41 137.7 0.1 2.1 2 0 0 2 2 2 1 Connector enhancer of kinase suppressor of ras SAM_1 PF00536.25 KFM13437.1 - 1.9e-14 53.5 0.3 5.5e-14 52.0 0.2 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 KFM13437.1 - 4.8e-14 52.4 2.0 1.5e-13 50.8 1.4 1.9 1 0 0 1 1 1 1 PH domain PDZ PF00595.19 KFM13437.1 - 4.8e-10 39.4 0.0 1.6e-08 34.6 0.0 2.7 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) SAM_2 PF07647.12 KFM13437.1 - 2.8e-09 36.7 1.0 7.7e-09 35.2 0.4 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PDZ_2 PF13180.1 KFM13437.1 - 0.005 16.6 0.1 0.021 14.7 0.0 2.0 2 0 0 2 2 2 1 PDZ domain PH_11 PF15413.1 KFM13437.1 - 0.017 15.3 7.8 0.089 13.0 5.4 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain PH_9 PF15410.1 KFM13437.1 - 0.047 13.8 1.7 1.8 8.7 0.7 2.7 2 1 0 2 2 2 0 Pleckstrin homology domain ApoO PF09769.4 KFM13438.1 - 7.1e-41 139.5 2.1 8.2e-41 139.3 0.0 1.9 2 0 0 2 2 2 1 Apolipoprotein O Zfx_Zfy_act PF04704.8 KFM13440.1 - 7.8e-139 462.1 18.0 7.8e-139 462.1 12.4 1.5 2 0 0 2 2 2 1 Zfx / Zfy transcription activation region zf-H2C2_2 PF13465.1 KFM13440.1 - 8.8e-40 133.0 119.7 3.3e-06 27.1 3.4 12.9 13 0 0 13 13 13 12 Zinc-finger double domain zf-C2H2 PF00096.21 KFM13440.1 - 9.2e-38 126.3 117.6 4.8e-06 26.5 1.9 12.3 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM13440.1 - 1.2e-29 100.3 103.0 0.00021 21.3 1.2 12.4 12 0 0 12 12 12 11 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KFM13440.1 - 2.3e-20 71.5 101.3 0.00019 21.4 3.2 12.1 12 0 0 12 12 12 8 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 KFM13440.1 - 1.8e-14 53.3 76.3 8.2e-05 22.6 0.1 11.6 11 0 0 11 11 11 7 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM13440.1 - 0.12 12.5 0.1 0.12 12.5 0.1 10.9 11 0 0 11 11 11 0 Zinc-finger of C2H2 type DUF2422 PF10337.4 KFM13441.1 - 0.097 11.4 1.8 0.15 10.8 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) ATG16 PF08614.6 KFM13441.1 - 0.23 11.2 27.7 0.55 10.0 5.6 3.4 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) Sec2p PF06428.6 KFM13441.1 - 0.63 9.9 13.2 0.18 11.6 0.5 3.5 2 2 1 3 3 3 0 GDP/GTP exchange factor Sec2p ADIP PF11559.3 KFM13441.1 - 1.3 8.9 25.2 0.72 9.7 4.0 2.9 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 KFM13441.1 - 1.7 7.7 5.7 6.4 5.8 0.7 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF445 PF04286.7 KFM13441.1 - 2.2 7.6 6.7 3.1 7.2 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Gon7 PF08738.5 KFM13441.1 - 3.4 7.7 8.1 15 5.6 0.3 3.4 2 1 1 3 3 3 0 Gon7 family FliJ PF02050.11 KFM13441.1 - 9.1 6.3 19.6 7.3 6.6 3.5 3.2 1 1 1 3 3 3 0 Flagellar FliJ protein GDI PF00996.13 KFM13442.1 - 7.6e-82 274.9 0.4 1.9e-69 234.1 0.1 2.4 2 1 0 2 2 2 2 GDP dissociation inhibitor NAD_binding_8 PF13450.1 KFM13442.1 - 0.011 15.7 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KFM13442.1 - 0.015 14.3 0.0 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase fn3 PF00041.16 KFM13443.1 - 7.8e-99 323.9 0.3 2.2e-10 40.5 0.0 9.8 9 1 0 9 9 9 9 Fibronectin type III domain Interfer-bind PF09294.5 KFM13443.1 - 7.3e-12 45.2 7.0 2.1 8.4 0.0 8.1 8 0 0 8 8 8 4 Interferon-alpha/beta receptor, fibronectin type III SusE PF14292.1 KFM13443.1 - 8.1e-06 25.6 0.0 8 6.3 0.0 6.2 8 0 0 8 8 8 2 SusE outer membrane protein Y_Y_Y PF07495.8 KFM13443.1 - 0.021 14.5 0.3 8.5 6.2 0.0 4.9 7 0 0 7 7 7 0 Y_Y_Y domain 7tm_1 PF00001.16 KFM13444.1 - 3.2e-52 177.2 16.3 3.9e-52 176.9 11.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.4 KFM13444.1 - 3e-09 36.4 17.1 6.2e-09 35.4 11.9 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.4 KFM13444.1 - 0.00039 19.6 18.3 0.0009 18.4 12.7 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx zf-LITAF-like PF10601.4 KFM13444.1 - 0.054 13.3 5.6 19 5.2 0.2 3.8 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain 7TM_GPCR_Srx PF10328.4 KFM13444.1 - 0.65 9.0 21.6 0.018 14.1 9.1 2.2 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx TNF PF00229.13 KFM13445.1 - 1.1e-43 147.7 0.3 1.6e-43 147.3 0.2 1.2 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family C1q PF00386.16 KFM13445.1 - 0.14 12.1 0.4 0.81 9.7 0.0 2.1 1 1 1 2 2 2 0 C1q domain Abhydrolase_3 PF07859.8 KFM13446.1 - 2.8e-53 180.6 0.1 1.7e-38 132.3 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 KFM13446.1 - 8e-07 28.0 0.0 1.2e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) COesterase PF00135.23 KFM13446.1 - 1.9e-06 26.9 0.1 0.00017 20.4 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_5 PF12695.2 KFM13446.1 - 8.3e-05 22.3 0.0 0.0001 22.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFM13446.1 - 0.00023 20.4 0.0 0.00085 18.5 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 KFM13446.1 - 0.01 14.7 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme PuR_N PF09182.5 KFM13446.1 - 0.023 14.2 0.0 0.057 13.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal AXE1 PF05448.7 KFM13446.1 - 0.069 11.6 0.0 0.11 11.0 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) RhoGEF PF00621.15 KFM13447.1 - 7.8e-39 133.3 0.6 2.6e-38 131.7 0.4 2.0 1 0 0 1 1 1 1 RhoGEF domain PTCB-BRCT PF12738.2 KFM13447.1 - 4.8e-23 80.7 3.9 5.2e-17 61.4 0.1 3.5 3 0 0 3 3 3 2 twin BRCT domain BRCT PF00533.21 KFM13447.1 - 3e-15 56.1 0.9 2.4e-06 27.6 0.0 3.0 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain NYD-SP12_N PF15015.1 KFM13448.1 - 1.3e-269 895.2 1.5 1.5e-269 895.0 1.0 1.0 1 0 0 1 1 1 1 Spermatogenesis-associated, N-terminal TPR_11 PF13414.1 KFM13448.1 - 3.4e-06 26.5 0.8 3.8e-05 23.2 0.0 2.6 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 KFM13448.1 - 2.9e-05 23.6 0.6 0.063 13.2 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFM13448.1 - 3.3e-05 23.3 0.3 0.11 12.1 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat EzrA PF06160.7 KFM13448.1 - 0.0046 15.2 0.1 0.0046 15.2 0.1 2.5 4 0 0 4 4 4 1 Septation ring formation regulator, EzrA TPR_12 PF13424.1 KFM13448.1 - 0.0086 15.9 0.7 2.2 8.2 0.1 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat RgpF PF05045.7 KFM13448.1 - 0.0091 14.5 0.2 0.014 13.9 0.1 1.2 1 0 0 1 1 1 1 Rhamnan synthesis protein F NADH_oxidored PF08040.6 KFM13448.1 - 0.095 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 MNLL subunit TPR_16 PF13432.1 KFM13448.1 - 0.12 13.1 0.5 12 6.6 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Rapsyn_N PF10579.4 KFM13448.1 - 0.18 11.5 1.1 41 4.0 0.0 3.2 3 0 0 3 3 3 0 Rapsyn N-terminal myristoylation and linker region Apc3 PF12895.2 KFM13448.1 - 0.21 11.7 2.1 0.79 9.8 0.5 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KFM13448.1 - 0.36 10.7 3.9 3.1 7.7 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat COesterase PF00135.23 KFM13449.1 - 2.8e-118 395.9 0.0 3.6e-118 395.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Sarcoglycan_2 PF05510.8 KFM13449.1 - 0.0016 16.8 0.2 0.0036 15.6 0.1 1.5 2 0 0 2 2 2 1 Sarcoglycan alpha/epsilon Abhydrolase_3 PF07859.8 KFM13449.1 - 0.02 14.4 0.0 0.052 13.1 0.0 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF4190 PF13828.1 KFM13450.1 - 0.093 12.2 0.2 0.15 11.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4190) Peptidase_M28 PF04389.12 KFM13451.1 - 3.8e-06 26.7 0.0 2.7e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M28 TFR_dimer PF04253.10 KFM13451.1 - 7.2e-05 22.3 0.0 0.00017 21.1 0.0 1.6 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain WD40 PF00400.27 KFM13452.1 - 1.6e-70 230.6 25.1 3.1e-13 49.0 0.0 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat eIF2A PF08662.6 KFM13452.1 - 2.5e-12 46.9 0.6 0.00078 19.2 0.1 3.4 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 KFM13452.1 - 3.1e-05 23.3 0.0 6 6.4 0.0 4.4 4 0 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.9 KFM13452.1 - 0.001 17.9 0.0 0.018 13.8 0.0 2.1 2 0 0 2 2 2 1 Coatomer WD associated region Nup160 PF11715.3 KFM13452.1 - 0.0034 15.5 4.3 0.27 9.3 0.1 3.7 2 1 1 3 3 3 2 Nucleoporin Nup120/160 IKI3 PF04762.7 KFM13452.1 - 0.014 13.2 0.5 0.19 9.5 0.3 2.5 1 1 0 1 1 1 0 IKI3 family TSP9 PF11493.3 KFM13452.1 - 0.05 14.1 0.2 0.11 13.1 0.1 1.4 1 0 0 1 1 1 0 Thylakoid soluble phosphoprotein TSP9 Nucleoporin_N PF08801.6 KFM13452.1 - 0.056 12.1 0.1 1.3 7.6 0.0 2.6 2 1 0 3 3 3 0 Nup133 N terminal like CaKB PF03185.10 KFM13453.1 - 7e-92 306.3 8.3 8.5e-92 306.0 5.7 1.0 1 0 0 1 1 1 1 Calcium-activated potassium channel, beta subunit KcnmB2_inactiv PF09303.5 KFM13453.1 - 1.4e-06 27.9 2.9 2.9e-06 26.9 2.0 1.6 1 0 0 1 1 1 1 KCNMB2, ball and chain domain tRNA-synt_1g PF09334.6 KFM13453.1 - 0.053 12.1 0.0 0.073 11.7 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (M) zf-met PF12874.2 KFM13454.1 - 2e-23 81.8 15.8 7.3e-09 35.5 0.2 3.4 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFM13454.1 - 1.5e-19 69.5 17.1 5.6e-07 29.5 0.2 3.3 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFM13454.1 - 2.5e-09 37.1 11.5 0.011 15.7 0.3 3.2 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.7 KFM13454.1 - 0.00073 19.0 18.3 0.083 12.4 2.1 3.6 3 1 0 3 3 3 2 U1 zinc finger AKAP95 PF04988.7 KFM13454.1 - 0.0031 17.3 8.3 0.012 15.3 0.3 3.0 3 0 0 3 3 3 2 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_4 PF13894.1 KFM13454.1 - 0.0062 16.7 10.6 1.1 9.7 0.2 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-DBF PF07535.7 KFM13454.1 - 2 8.1 7.7 2 8.1 0.3 2.9 3 0 0 3 3 3 0 DBF zinc finger PI3Ka PF00613.15 KFM13455.1 - 4.7e-73 244.3 2.0 8.9e-73 243.4 1.4 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 KFM13455.1 - 4.8e-54 183.3 1.6 8.2e-54 182.5 0.5 1.9 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_rbd PF00794.13 KFM13455.1 - 1.7e-39 134.0 1.0 1.2e-37 128.0 0.4 2.9 2 0 0 2 2 2 1 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.19 KFM13455.1 - 1.7e-32 112.1 0.0 3.2e-32 111.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_p85B PF02192.11 KFM13455.1 - 1.3e-31 107.8 0.3 3.2e-31 106.5 0.2 1.7 1 0 0 1 1 1 1 PI3-kinase family, p85-binding domain DUF3023 PF11224.3 KFM13455.1 - 0.038 13.6 0.9 7.3 6.2 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3023) Fzo_mitofusin PF04799.8 KFM13456.1 - 8e-80 266.2 4.9 8e-80 266.2 3.4 2.5 2 1 0 2 2 2 1 fzo-like conserved region Dynamin_N PF00350.18 KFM13456.1 - 1.8e-23 83.2 0.0 1.8e-23 83.2 0.0 3.6 3 1 1 4 4 4 1 Dynamin family MMR_HSR1 PF01926.18 KFM13456.1 - 5.4e-07 29.5 0.6 2.3e-06 27.5 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase Apolipoprotein PF01442.13 KFM13456.1 - 0.014 14.9 14.9 0.035 13.6 0.4 3.0 2 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain AAA_29 PF13555.1 KFM13456.1 - 0.078 12.5 0.0 0.25 10.9 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.1 KFM13456.1 - 0.17 12.2 16.0 1.1 9.5 0.2 3.6 3 1 0 3 3 3 0 AAA domain DUF1664 PF07889.7 KFM13456.1 - 7.5 6.3 11.0 0.44 10.3 0.8 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) WD40 PF00400.27 KFM13457.1 - 1.8e-54 179.7 26.9 1.4e-09 37.4 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KFM13457.1 - 3.3e-05 23.6 0.0 0.11 12.2 0.0 2.6 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A UL11 PF11094.3 KFM13457.1 - 0.0075 16.0 1.0 0.021 14.6 0.2 2.1 2 0 0 2 2 2 1 Membrane-associated tegument protein Nucleoporin_N PF08801.6 KFM13457.1 - 0.039 12.7 1.2 2.1 7.0 0.1 3.1 3 1 0 3 3 3 0 Nup133 N terminal like Actin PF00022.14 KFM13458.1 - 2.6e-111 371.8 0.0 9.2e-94 314.0 0.0 2.0 2 0 0 2 2 2 2 Actin MobA_MobL PF03389.10 KFM13458.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 MobA/MobL family MRP-L47 PF06984.8 KFM13459.1 - 6.1e-36 122.1 1.4 1.2e-35 121.3 1.0 1.5 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) NDUF_B5 PF09781.4 KFM13460.1 - 2.7e-77 258.2 1.1 3e-77 258.1 0.7 1.0 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit UCH PF00443.24 KFM13461.1 - 1.8e-49 168.2 0.0 2.5e-49 167.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 KFM13461.1 - 1.3e-20 72.5 0.1 6.7e-10 38.5 0.0 3.0 3 0 0 3 3 3 2 UBA/TS-N domain zf-UBP PF02148.14 KFM13461.1 - 2.9e-17 62.5 1.3 1.1e-14 54.2 0.0 2.8 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 KFM13461.1 - 1.9e-15 57.1 0.0 1.5e-14 54.1 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA_3 PF09288.5 KFM13461.1 - 0.12 11.9 0.6 2.9 7.5 0.0 2.8 3 0 0 3 3 3 0 Fungal ubiquitin-associated domain TPR_1 PF00515.23 KFM13462.1 - 1.6e-26 90.7 1.0 1.7e-05 24.2 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 KFM13462.1 - 9.8e-25 86.0 5.9 3.3e-11 42.6 0.0 4.3 2 2 3 5 5 5 5 TPR repeat TPR_2 PF07719.12 KFM13462.1 - 1.8e-21 74.2 7.2 0.00018 21.1 0.0 6.1 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 KFM13462.1 - 8.5e-18 63.0 9.5 0.0008 19.4 0.3 5.9 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 KFM13462.1 - 1.2e-15 57.6 5.0 0.00094 19.7 0.0 4.6 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.1 KFM13462.1 - 1.8e-14 52.8 11.4 0.0011 19.4 0.7 6.4 3 2 4 7 7 6 5 Tetratricopeptide repeat TPR_19 PF14559.1 KFM13462.1 - 5.6e-13 49.0 6.9 0.00044 20.5 1.8 4.6 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_9 PF13371.1 KFM13462.1 - 6.9e-11 41.8 2.1 0.00043 20.0 0.3 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFM13462.1 - 3.1e-10 39.0 0.8 0.34 10.7 0.0 5.3 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFM13462.1 - 7.7e-10 38.5 1.1 1.1e-05 25.2 0.1 3.8 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_20 PF14561.1 KFM13462.1 - 3e-09 36.8 4.2 0.00021 21.3 0.4 4.6 2 2 1 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 KFM13462.1 - 1.1e-07 31.9 1.3 0.0056 16.7 1.1 2.9 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KFM13462.1 - 1.2e-07 31.0 3.1 0.21 11.4 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFM13462.1 - 3.4e-07 30.2 3.7 4.1 8.0 0.1 6.0 6 0 0 6 6 5 1 Tetratricopeptide repeat DUF4248 PF14053.1 KFM13462.1 - 0.00079 18.9 0.3 0.0022 17.5 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4248) TPR_10 PF13374.1 KFM13462.1 - 0.0029 17.4 7.8 2.1 8.3 0.2 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_3 PF07720.7 KFM13462.1 - 0.01 15.6 0.0 5 7.0 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 KFM13462.1 - 0.011 14.9 4.8 9.6 5.5 0.3 3.6 3 0 0 3 3 3 0 SHNi-TPR Fis1_TPR_C PF14853.1 KFM13462.1 - 0.96 9.3 3.2 41 4.1 0.1 3.6 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.12 KFM13462.1 - 1.1 9.6 6.8 3.9 7.7 0.1 3.2 3 0 0 3 3 3 0 Bacterial transcriptional activator domain TPR_11 PF13414.1 KFM13463.1 - 2.9e-16 58.8 2.7 1.1e-12 47.4 0.0 2.9 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 KFM13463.1 - 5.2e-13 47.9 0.2 0.0006 19.3 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFM13463.1 - 5.3e-12 44.6 3.6 0.00049 19.8 0.0 4.9 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFM13463.1 - 4.8e-07 29.8 0.1 0.041 14.5 0.0 3.8 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFM13463.1 - 2.1e-06 27.5 1.0 0.024 14.5 0.0 3.1 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 KFM13463.1 - 3.1e-06 26.9 0.0 5.9e-05 22.8 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFM13463.1 - 4.1e-06 26.1 6.6 0.18 11.6 0.0 4.7 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFM13463.1 - 5.1e-06 27.0 1.2 7.4e-05 23.3 0.0 2.8 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFM13463.1 - 1.5e-05 24.7 0.9 0.00033 20.6 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFM13463.1 - 0.00027 21.2 2.7 0.0086 16.3 0.0 3.1 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFM13463.1 - 0.13 12.0 1.1 50 4.0 0.0 4.0 4 1 0 4 4 3 0 Tetratricopeptide repeat HeLo PF14479.1 KFM13463.1 - 2.8 7.6 19.6 2.3 7.8 9.3 2.9 2 1 1 3 3 3 0 Prion-inhibition and propagation HrpB7 PF09486.5 KFM13464.1 - 0.00048 20.1 8.5 0.00048 20.1 5.9 7.9 4 3 5 10 10 10 1 Bacterial type III secretion protein (HrpB7) CENP-F_leu_zip PF10473.4 KFM13464.1 - 0.0011 18.8 21.0 0.0011 18.8 14.6 9.9 2 2 5 8 8 8 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 KFM13464.1 - 0.63 9.1 32.4 0.18 10.9 3.1 5.7 2 2 0 5 5 5 0 Reovirus sigma C capsid protein FXR1P_C PF12235.3 KFM13465.1 - 7.6e-65 217.7 18.5 7.6e-65 217.7 12.8 2.4 2 0 0 2 2 2 1 Fragile X-related 1 protein C terminal KH_1 PF00013.24 KFM13465.1 - 1.1e-18 66.6 1.6 5e-09 35.6 0.7 2.7 2 0 0 2 2 2 2 KH domain Agenet PF05641.7 KFM13465.1 - 1.3e-10 41.2 0.1 1.3e-10 41.2 0.1 2.0 2 0 0 2 2 2 1 Agenet domain KH_3 PF13014.1 KFM13465.1 - 3.7e-06 26.4 4.9 6.2e-06 25.7 0.3 3.2 4 0 0 4 4 4 1 KH domain KH_2 PF07650.12 KFM13465.1 - 0.00026 20.4 0.8 0.099 12.2 0.0 2.6 2 0 0 2 2 2 2 KH domain KH_4 PF13083.1 KFM13465.1 - 0.13 11.9 5.0 0.63 9.7 0.2 3.3 3 1 1 4 4 4 0 KH domain Tombus_movement PF05318.7 KFM13465.1 - 7.4 7.2 8.0 0.44 11.1 0.2 2.8 2 1 0 2 2 2 0 Tombusvirus movement protein SOXp PF12336.3 KFM13466.1 - 1.8e-29 102.2 4.3 1.8e-29 102.2 3.0 2.5 3 0 0 3 3 3 1 SOX transcription factor HMG_box PF00505.14 KFM13466.1 - 2.8e-27 94.7 3.2 4.6e-27 94.0 2.2 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFM13466.1 - 9.3e-12 45.1 1.8 1.7e-11 44.3 1.3 1.4 1 0 0 1 1 1 1 HMG-box domain E1-E2_ATPase PF00122.15 KFM13467.1 - 1e-16 60.6 0.1 1e-16 60.6 0.0 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KFM13467.1 - 6.9e-14 52.7 0.0 8.7e-13 49.1 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFM13467.1 - 8.8e-13 48.8 0.0 2.1e-12 47.6 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFM13467.1 - 4.8e-12 45.6 0.0 2.1e-11 43.6 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFM13467.1 - 0.00024 20.7 0.0 0.0072 15.9 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase FIST_C PF10442.4 KFM13467.1 - 0.087 12.7 0.1 3.4 7.6 0.0 3.0 3 0 0 3 3 3 0 FIST C domain Cullin_binding PF03556.10 KFM13468.1 - 1.4e-25 89.6 4.6 7.8e-25 87.2 0.6 2.9 2 1 0 2 2 2 1 Cullin binding UBA_4 PF14555.1 KFM13468.1 - 5.8e-10 38.5 0.6 1.5e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 UBA-like domain CPSase_L_D2 PF02786.12 KFM13469.1 - 3.6e-77 258.4 0.1 6.6e-77 257.5 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 KFM13469.1 - 2.3e-45 153.1 0.9 1.4e-44 150.7 0.2 2.3 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KFM13469.1 - 3.3e-36 123.5 0.0 1.6e-35 121.2 0.0 2.2 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 KFM13469.1 - 1.4e-16 59.8 0.6 5e-16 58.1 0.4 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 KFM13469.1 - 3.3e-16 58.9 0.1 6.9e-16 57.9 0.1 1.5 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 KFM13469.1 - 4.7e-16 59.0 0.1 1e-15 57.9 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KFM13469.1 - 3.5e-13 49.4 0.0 1.1e-12 47.7 0.0 1.8 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KFM13469.1 - 2.2e-09 36.9 0.4 5e-09 35.7 0.1 1.7 2 0 0 2 2 1 1 ATP-grasp domain RimK PF08443.6 KFM13469.1 - 2.8e-07 30.1 0.0 1.1e-06 28.2 0.0 1.9 1 1 0 1 1 1 1 RimK-like ATP-grasp domain Biotin_lipoyl_2 PF13533.1 KFM13469.1 - 6.9e-07 28.8 1.3 0.00074 19.1 0.0 3.1 3 0 0 3 3 3 2 Biotin-lipoyl like HlyD_3 PF13437.1 KFM13469.1 - 1.3e-06 28.7 0.1 0.049 13.9 0.0 2.7 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.9 KFM13469.1 - 1.1e-05 25.2 0.0 2.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 KFM13469.1 - 0.00038 19.8 0.0 0.032 13.5 0.0 2.2 2 0 0 2 2 2 1 HlyD family secretion protein GARS_A PF01071.14 KFM13469.1 - 0.00099 18.7 0.0 0.0019 17.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RnfC_N PF13375.1 KFM13469.1 - 0.026 14.2 0.4 0.071 12.8 0.3 1.7 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain ATPgrasp_ST PF14397.1 KFM13469.1 - 0.027 13.5 0.1 0.11 11.6 0.0 2.0 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Toxin_59 PF15537.1 KFM13469.1 - 0.08 13.0 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Putative toxin 59 Lamp PF01299.12 KFM13470.1 - 4.9e-22 78.4 3.0 5.2e-22 78.3 2.1 1.0 1 0 0 1 1 1 1 Lysosome-associated membrane glycoprotein (Lamp) SOBP PF15279.1 KFM13472.1 - 5.5 7.2 8.5 6.2 7.1 5.9 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein RhoGEF PF00621.15 KFM13473.1 - 2.5e-38 131.7 6.6 2.5e-38 131.7 4.6 2.9 3 1 0 3 3 3 1 RhoGEF domain CRAL_TRIO_2 PF13716.1 KFM13473.1 - 9.1e-15 54.8 0.0 2.9e-14 53.2 0.0 1.9 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain PH PF00169.24 KFM13473.1 - 9.9e-08 32.1 1.1 2.6e-07 30.8 0.8 1.7 1 0 0 1 1 1 1 PH domain Spectrin PF00435.16 KFM13473.1 - 9.5e-05 22.6 0.8 9.5e-05 22.6 0.6 4.7 3 1 2 5 5 5 2 Spectrin repeat PH_10 PF15411.1 KFM13473.1 - 0.0019 18.3 1.5 0.0063 16.6 0.4 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain CRAL_TRIO PF00650.15 KFM13473.1 - 0.046 13.2 0.0 0.13 11.7 0.0 1.8 1 0 0 1 1 1 0 CRAL/TRIO domain Galactosyl_T PF01762.16 KFM13474.1 - 4.5e-47 160.1 0.1 6.7e-47 159.6 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.11 KFM13474.1 - 0.00029 20.1 0.0 0.0006 19.0 0.0 1.6 1 1 0 1 1 1 1 Fringe-like AAA PF00004.24 KFM13475.1 - 3.8e-17 62.7 0.0 1.5e-16 60.8 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 KFM13475.1 - 4.4e-17 61.8 0.1 8.5e-17 60.9 0.1 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KFM13475.1 - 2.9e-12 46.5 0.0 1.9e-10 40.6 0.0 2.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 KFM13475.1 - 3.9e-09 35.7 0.0 9e-05 21.3 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 KFM13475.1 - 2.6e-06 27.0 0.0 6.2e-06 25.8 0.0 1.8 1 1 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KFM13475.1 - 2e-05 24.7 0.0 0.0003 20.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFM13475.1 - 2.5e-05 24.3 0.0 0.0015 18.5 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_11 PF13086.1 KFM13475.1 - 6.1e-05 22.7 0.2 0.0002 21.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KFM13475.1 - 0.00027 20.8 0.0 0.00058 19.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KFM13475.1 - 0.00027 20.5 0.0 0.00088 18.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain DUF815 PF05673.8 KFM13475.1 - 0.0003 19.7 0.0 0.00059 18.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 KFM13475.1 - 0.0012 18.1 0.0 0.038 13.1 0.0 2.9 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 KFM13475.1 - 0.0027 16.7 0.0 0.0055 15.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 KFM13475.1 - 0.0032 17.0 0.1 0.011 15.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.8 KFM13475.1 - 0.0038 16.7 0.0 0.0075 15.8 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_5 PF07728.9 KFM13475.1 - 0.015 15.0 0.0 0.08 12.6 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.13 KFM13475.1 - 0.019 14.4 0.0 0.43 10.0 0.0 2.3 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Arch_ATPase PF01637.13 KFM13475.1 - 0.021 14.5 0.7 0.86 9.2 0.0 2.4 1 1 2 3 3 3 0 Archaeal ATPase DUF2075 PF09848.4 KFM13475.1 - 0.024 13.6 0.0 0.07 12.0 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 KFM13475.1 - 0.041 13.3 0.1 1.7 8.0 0.0 2.6 2 1 1 3 3 3 0 DEAD/DEAH box helicase AAA_3 PF07726.6 KFM13475.1 - 0.052 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 KFM13475.1 - 0.067 12.4 0.0 6.5 5.9 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_18 PF13238.1 KFM13475.1 - 0.083 13.1 0.1 2.2 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KFM13475.1 - 0.11 11.9 0.1 1.1 8.5 0.1 2.6 1 1 0 1 1 1 0 AAA-like domain ResIII PF04851.10 KFM13475.1 - 0.12 12.2 0.0 0.32 10.7 0.0 1.9 2 1 0 2 2 1 0 Type III restriction enzyme, res subunit AAA_25 PF13481.1 KFM13475.1 - 0.14 11.5 0.0 0.36 10.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain DEAD PF00270.24 KFM13476.1 - 4.8e-42 143.3 1.2 8.5e-42 142.5 0.2 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFM13476.1 - 1.5e-27 95.2 0.7 4.3e-27 93.7 0.2 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KFM13476.1 - 0.00012 21.7 0.1 0.00026 20.6 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 KFM13476.1 - 0.00031 20.6 0.1 0.00077 19.3 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KFM13476.1 - 0.0034 17.0 0.1 0.0071 15.9 0.0 1.5 2 0 0 2 2 2 1 AAA domain SNF2_N PF00176.18 KFM13476.1 - 0.023 13.5 0.0 0.037 12.8 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_22 PF13401.1 KFM13476.1 - 0.032 14.3 0.3 0.31 11.1 0.2 2.5 1 1 0 1 1 1 0 AAA domain tRNA-synt_1b PF00579.20 KFM13476.1 - 0.037 13.1 0.1 0.11 11.5 0.0 1.8 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) Flavi_DEAD PF07652.9 KFM13476.1 - 0.058 13.1 0.0 0.25 11.0 0.0 2.0 2 0 0 2 2 2 0 Flavivirus DEAD domain Helicase_RecD PF05127.9 KFM13476.1 - 0.089 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Helicase Cystatin PF00031.16 KFM13477.1 - 2.4e-40 136.5 3.2 7.5e-21 74.0 0.1 2.1 2 0 0 2 2 2 2 Cystatin domain Cathelicidins PF00666.12 KFM13477.1 - 3.4e-10 39.9 0.4 0.0011 19.0 0.0 2.4 2 0 0 2 2 2 2 Cathelicidin Spp-24 PF07448.6 KFM13477.1 - 0.005 16.8 3.2 0.0091 15.9 0.5 2.2 2 0 0 2 2 2 1 Secreted phosphoprotein 24 (Spp-24) Cystatin PF00031.16 KFM13478.1 - 1.6e-20 73.0 0.0 2.5e-12 46.7 0.0 2.4 2 0 0 2 2 2 2 Cystatin domain Peptidase_C48 PF02902.14 KFM13479.1 - 1.5e-43 148.9 2.1 2.7e-43 148.0 1.4 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DEK_C PF08766.6 KFM13479.1 - 0.002 17.8 0.1 0.0072 16.0 0.0 2.0 2 0 0 2 2 2 1 DEK C terminal domain RNA_pol_Rpb8 PF03870.10 KFM13480.1 - 1.3e-55 187.3 0.1 1.5e-55 187.1 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 EPO_TPO PF00758.13 KFM13481.1 - 1.3e-22 80.1 0.1 1.7e-22 79.8 0.1 1.2 1 0 0 1 1 1 1 Erythropoietin/thrombopoietin CHRD PF07452.7 KFM13482.1 - 6.1e-61 204.2 0.1 1.9e-26 92.9 0.0 3.1 3 0 0 3 3 3 3 CHRD domain Amnionless PF14828.1 KFM13482.1 - 0.084 11.3 5.7 0.12 10.7 3.9 1.2 1 0 0 1 1 1 0 Amnionless VWC PF00093.13 KFM13482.1 - 0.39 10.8 7.8 0.65 10.1 5.4 1.4 1 0 0 1 1 1 0 von Willebrand factor type C domain CHRD PF07452.7 KFM13483.1 - 3.9e-09 37.1 0.0 4.3e-09 37.0 0.0 1.0 1 0 0 1 1 1 1 CHRD domain Voltage_CLC PF00654.15 KFM13484.1 - 7.6e-59 199.5 26.6 1.8e-33 116.0 5.6 2.8 2 1 1 3 3 3 2 Voltage gated chloride channel FAM131 PF15010.1 KFM13485.1 - 4.6e-40 138.2 0.2 6.1e-40 137.8 0.1 1.1 1 0 0 1 1 1 1 Putative cell signalling MIF4G PF02854.14 KFM13486.1 - 1.4e-67 227.2 9.5 1.4e-67 227.2 6.6 1.8 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 KFM13486.1 - 1.6e-26 92.1 0.3 8e-26 89.9 0.1 2.3 2 1 0 2 2 2 1 MA3 domain PC_rep PF01851.17 KFM13487.1 - 5.7e-25 86.1 17.9 1.2e-06 28.4 0.1 9.1 9 0 0 9 9 9 5 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KFM13487.1 - 4.7e-05 23.5 0.4 0.34 11.2 0.0 4.5 4 1 0 4 4 4 2 HEAT repeats DUF2370 PF10176.4 KFM13487.1 - 0.3 10.3 0.8 0.98 8.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) Peptidase_M13_N PF05649.8 KFM13488.1 - 1.2e-115 386.7 0.0 1.5e-115 386.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 KFM13488.1 - 9.7e-31 106.5 0.3 2.3e-30 105.3 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M48 PF01435.13 KFM13488.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M48 DUF2352 PF09817.4 KFM13490.1 - 0.086 10.9 0.2 0.12 10.5 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2352) CP2 PF04516.10 KFM13491.1 - 2.1e-72 243.0 0.0 3.3e-72 242.3 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor DAZAP2 PF11029.3 KFM13492.1 - 2.9e-27 95.8 5.6 2.9e-27 95.8 3.9 1.4 2 0 0 2 2 2 1 DAZ associated protein 2 (DAZAP2) Ras PF00071.17 KFM13493.1 - 5.2e-26 90.9 0.0 5.8e-26 90.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM13493.1 - 5.6e-10 39.7 0.0 8.2e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Ribosomal_L21p PF00829.16 KFM13494.1 - 1.2e-21 76.6 0.1 3.7e-21 75.0 0.0 1.7 2 0 0 2 2 2 1 Ribosomal prokaryotic L21 protein AAA_11 PF13086.1 KFM13495.1 - 1.6e-59 201.3 0.3 1.6e-59 201.3 0.2 2.7 3 1 0 3 3 3 1 AAA domain AAA_12 PF13087.1 KFM13495.1 - 2.4e-52 177.2 0.0 9.7e-52 175.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain R3H PF01424.17 KFM13495.1 - 1.1e-15 57.0 0.1 2.9e-15 55.7 0.1 1.8 1 0 0 1 1 1 1 R3H domain AAA_19 PF13245.1 KFM13495.1 - 6.5e-15 54.6 1.5 2.2e-13 49.7 0.1 3.3 3 0 0 3 3 3 1 Part of AAA domain AAA_30 PF13604.1 KFM13495.1 - 8.2e-13 48.3 1.6 7.3e-11 42.0 0.1 3.4 2 1 0 2 2 2 1 AAA domain Helicase_RecD PF05127.9 KFM13495.1 - 1e-09 38.2 0.1 0.00038 20.1 0.1 3.4 2 1 0 2 2 2 2 Helicase ResIII PF04851.10 KFM13495.1 - 2.6e-09 37.1 0.0 5.2e-08 32.9 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 KFM13495.1 - 2.2e-08 33.9 0.7 0.26 10.7 0.0 4.0 4 0 0 4 4 4 3 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 KFM13495.1 - 8.9e-05 22.0 0.2 0.00043 19.8 0.1 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.4 KFM13495.1 - 0.00013 21.0 0.2 0.0021 17.0 0.2 2.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 KFM13495.1 - 0.00021 20.7 0.1 0.00081 18.8 0.0 2.0 1 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KFM13495.1 - 0.00025 21.2 0.1 0.0027 17.8 0.1 2.6 1 1 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.9 KFM13495.1 - 0.00031 20.5 0.2 0.00097 18.9 0.0 1.9 2 0 0 2 2 1 1 Flavivirus DEAD domain FtsK_SpoIIIE PF01580.13 KFM13495.1 - 0.00053 19.5 0.0 0.0014 18.1 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family zf-AN1 PF01428.11 KFM13495.1 - 0.0013 18.6 7.7 0.0025 17.6 5.4 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger IstB_IS21 PF01695.12 KFM13495.1 - 0.0017 17.8 0.0 0.0048 16.3 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein UvrD-helicase PF00580.16 KFM13495.1 - 0.0021 17.4 0.0 0.01 15.1 0.0 1.9 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.1 KFM13495.1 - 0.0023 17.9 0.3 0.0095 15.9 0.1 2.1 2 0 0 2 2 2 1 AAA ATPase domain Zot PF05707.7 KFM13495.1 - 0.0026 17.2 0.3 0.056 12.9 0.0 2.5 1 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA PF00004.24 KFM13495.1 - 0.003 17.7 0.4 0.0091 16.1 0.3 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 KFM13495.1 - 0.0064 15.4 0.0 0.013 14.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_17 PF13207.1 KFM13495.1 - 0.0069 17.1 0.4 0.14 12.9 0.4 2.9 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 KFM13495.1 - 0.01 15.5 0.0 0.028 14.1 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 KFM13495.1 - 0.011 16.0 0.0 0.038 14.2 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_10 PF12846.2 KFM13495.1 - 0.013 14.9 0.0 0.029 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain DAP3 PF10236.4 KFM13495.1 - 0.037 12.9 0.0 0.077 11.9 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_18 PF13238.1 KFM13495.1 - 0.04 14.2 0.0 0.13 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.1 KFM13495.1 - 0.046 13.8 0.0 0.15 12.2 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_28 PF13521.1 KFM13495.1 - 0.047 13.6 0.2 2.1 8.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KFM13495.1 - 0.05 13.9 0.3 0.64 10.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.9 KFM13495.1 - 0.065 12.1 0.0 0.62 8.9 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase PhoH PF02562.11 KFM13495.1 - 0.077 12.2 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein NTPase_1 PF03266.10 KFM13495.1 - 0.088 12.5 0.1 0.42 10.3 0.0 2.1 2 0 0 2 2 2 0 NTPase CobA_CobO_BtuR PF02572.10 KFM13495.1 - 0.097 12.2 0.1 17 4.9 0.0 2.6 2 0 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP ArgK PF03308.11 KFM13495.1 - 0.13 10.9 0.7 0.34 9.6 0.0 2.0 2 0 0 2 2 2 0 ArgK protein C2 PF00168.25 KFM13496.1 - 8.3e-23 80.0 0.0 2e-15 56.3 0.1 2.3 2 0 0 2 2 2 2 C2 domain DOCK-C2 PF14429.1 KFM13496.1 - 0.012 15.3 0.0 2.5 7.7 0.0 2.2 2 0 0 2 2 2 0 C2 domain in Dock180 and Zizimin proteins PSS PF03034.10 KFM13497.1 - 9.8e-115 382.7 15.3 1.6e-114 382.0 10.6 1.4 1 0 0 1 1 1 1 Phosphatidyl serine synthase DUF3104 PF11302.3 KFM13497.1 - 2.3 7.6 4.4 3.3 7.1 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3104) Anoctamin PF04547.7 KFM13498.1 - 7.2e-126 420.4 19.1 9.5e-126 420.0 13.2 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel TIR PF01582.15 KFM13499.1 - 7.5e-18 64.3 0.0 1.1e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.1 KFM13499.1 - 6.4e-09 35.8 0.1 3.3e-08 33.6 0.0 2.2 2 1 1 3 3 3 1 TIR domain Arm PF00514.18 KFM13500.1 - 1.5e-19 69.0 0.1 2e-06 27.3 0.0 5.6 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFM13500.1 - 0.00034 20.8 0.0 0.0035 17.5 0.0 2.7 2 1 0 2 2 2 1 HEAT repeats DUF383 PF04063.9 KFM13500.1 - 0.02 14.4 0.1 10 5.6 0.0 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF383) Proteasom_PSMB PF10508.4 KFM13500.1 - 0.021 13.0 0.1 0.051 11.8 0.0 1.6 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit HEAT PF02985.17 KFM13500.1 - 0.041 13.9 0.0 0.35 11.0 0.0 2.6 2 0 0 2 2 2 0 HEAT repeat Adaptin_N PF01602.15 KFM13500.1 - 0.099 10.9 0.1 0.25 9.6 0.0 1.6 2 0 0 2 2 2 0 Adaptin N terminal region CHGN PF05679.11 KFM13501.1 - 2.4e-21 76.0 0.0 1.1e-20 73.9 0.0 1.8 1 1 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase PA14 PF07691.7 KFM13501.1 - 3.9e-18 65.4 0.0 8.1e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Glyco_transf_7C PF02709.9 KFM13501.1 - 3.6e-13 48.7 0.5 7e-13 47.8 0.4 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFM13501.1 - 1.9e-05 23.8 0.3 0.0063 15.6 0.1 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Thioredoxin_8 PF13905.1 KFM13501.1 - 0.038 14.1 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like MIP-T3 PF10243.4 KFM13501.1 - 0.084 11.3 44.0 0.14 10.5 30.5 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF4045 PF13254.1 KFM13501.1 - 6.6 5.8 24.3 0.18 11.0 11.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) DUF1510 PF07423.6 KFM13501.1 - 7.2 5.9 54.9 0.29 10.4 29.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Dispanin PF04505.7 KFM13502.1 - 1.4e-19 69.3 0.1 1.7e-19 69.0 0.0 1.0 1 0 0 1 1 1 1 Interferon-induced transmembrane protein DUF4190 PF13828.1 KFM13502.1 - 0.0008 18.9 1.4 0.0024 17.3 0.9 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4190) DUF3278 PF11683.3 KFM13502.1 - 0.092 12.7 0.0 0.094 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) Fijivirus_P9-2 PF06837.6 KFM13502.1 - 9.2 5.3 6.5 1.5 7.8 0.9 1.9 2 0 0 2 2 2 0 Fijivirus P9-2 protein Dispanin PF04505.7 KFM13503.1 - 1.6e-24 85.2 0.1 2.3e-24 84.7 0.1 1.2 1 0 0 1 1 1 1 Interferon-induced transmembrane protein ScdA_N PF04405.9 KFM13503.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown function (DUF542) Glyco_hydro_65m PF03632.10 KFM13504.1 - 1.8e-83 280.3 0.0 4.8e-82 275.5 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain SIR2 PF02146.12 KFM13505.1 - 7.1e-56 188.7 0.0 9.1e-56 188.3 0.0 1.1 1 0 0 1 1 1 1 Sir2 family Ric8 PF10165.4 KFM13506.1 - 1.7e-168 561.1 1.1 1.7e-168 561.1 0.8 1.4 2 0 0 2 2 2 1 Guanine nucleotide exchange factor synembryn Occludin_ELL PF07303.8 KFM13506.1 - 0.023 15.3 0.2 0.67 10.7 0.1 2.5 2 0 0 2 2 2 0 Occludin homology domain Uteroglobin PF01099.12 KFM13507.1 - 6.1e-10 38.7 0.0 7.2e-10 38.5 0.0 1.0 1 0 0 1 1 1 1 Uteroglobin family HEAT_EZ PF13513.1 KFM13507.1 - 0.046 14.2 0.1 0.75 10.3 0.0 2.0 2 0 0 2 2 2 0 HEAT-like repeat INCENP_ARK-bind PF03941.10 KFM13508.1 - 3.2e-20 71.7 0.0 9.6e-20 70.1 0.0 1.9 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region NACHT PF05729.7 KFM13509.1 - 9.4e-43 145.7 0.0 2.4e-42 144.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain PYRIN PF02758.11 KFM13509.1 - 1.4e-17 63.1 0.0 3.1e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 PAAD/DAPIN/Pyrin domain FISNA PF14484.1 KFM13509.1 - 1.6e-12 47.2 0.1 2.8e-12 46.4 0.1 1.4 1 0 0 1 1 1 1 Fish-specific NACHT associated domain LRR_6 PF13516.1 KFM13509.1 - 2.4e-09 36.2 0.6 0.073 13.1 0.0 3.8 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.2 KFM13509.1 - 1.4e-08 34.1 0.0 0.00076 19.0 0.0 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) AAA_16 PF13191.1 KFM13509.1 - 5.9e-05 23.1 0.5 0.0029 17.6 0.0 3.3 2 1 1 3 3 3 1 AAA ATPase domain LRR_7 PF13504.1 KFM13509.1 - 0.00021 20.9 1.8 16 6.2 0.2 4.2 3 0 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.28 KFM13509.1 - 0.0005 19.7 0.5 19 5.7 0.0 4.1 3 0 0 3 3 3 0 Leucine Rich Repeat AAA_22 PF13401.1 KFM13509.1 - 0.001 19.2 0.0 0.0032 17.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain LRR_8 PF13855.1 KFM13509.1 - 0.0026 17.4 1.1 0.69 9.7 0.1 2.8 2 0 0 2 2 2 1 Leucine rich repeat NB-ARC PF00931.17 KFM13509.1 - 0.014 14.2 0.1 0.041 12.7 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.1 KFM13509.1 - 0.017 14.8 0.0 1 9.1 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain AAA_14 PF13173.1 KFM13509.1 - 0.089 12.6 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KFM13509.1 - 0.17 11.2 0.0 0.36 10.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Tankyrase_bdg_C PF15327.1 KFM13510.1 - 1.6e-54 184.8 12.2 2.1e-54 184.3 8.5 1.1 1 0 0 1 1 1 1 Tankyrase binding protein C terminal domain SSrecog PF03531.9 KFM13511.1 - 1.1e-82 276.6 0.1 1.8e-82 275.9 0.0 1.3 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) HMG_box PF00505.14 KFM13511.1 - 1.2e-24 86.3 5.8 1.2e-24 86.3 4.1 2.5 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFM13511.1 - 1e-13 51.4 5.8 1e-13 51.4 4.0 2.5 3 0 0 3 3 3 1 HMG-box domain Rtt106 PF08512.7 KFM13511.1 - 1.5e-12 47.3 0.0 4.5e-12 45.7 0.0 1.9 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Daxx PF03344.10 KFM13511.1 - 3.9 5.8 24.7 5.9 5.2 17.1 1.2 1 0 0 1 1 1 0 Daxx Family SNAP PF14938.1 KFM13512.1 - 2.6e-107 358.1 19.2 2.9e-107 358.0 13.3 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 KFM13512.1 - 1.3e-09 37.8 12.4 4.7e-06 26.4 3.0 3.0 1 1 0 2 2 2 2 Tetratricopeptide repeat NSF PF02071.15 KFM13512.1 - 2.2e-06 27.1 34.6 0.44 11.2 1.8 8.8 8 1 1 9 9 8 2 Aromatic-di-Alanine (AdAR) repeat TPR_7 PF13176.1 KFM13512.1 - 7.8e-06 25.3 9.6 0.074 12.8 0.0 5.6 5 1 2 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFM13512.1 - 0.00011 21.7 18.9 0.00048 19.7 1.0 4.1 2 1 3 5 5 5 3 TPR repeat TPR_10 PF13374.1 KFM13512.1 - 0.00016 21.4 2.7 0.49 10.4 0.0 4.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFM13512.1 - 0.00019 20.9 11.6 0.077 12.8 0.5 5.1 3 1 2 5 5 5 1 Tetratricopeptide repeat Spatacsin_C PF14649.1 KFM13512.1 - 0.0011 17.8 10.3 0.0064 15.4 1.1 2.5 1 1 0 2 2 2 2 Spatacsin C-terminus TPR_2 PF07719.12 KFM13512.1 - 0.0029 17.4 13.8 3.6 7.7 0.2 5.2 3 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFM13512.1 - 0.008 16.7 0.9 34 5.4 0.0 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFM13512.1 - 0.037 14.3 6.3 0.1 12.9 1.1 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat Foie-gras_1 PF11817.3 KFM13512.1 - 0.038 13.4 6.5 0.081 12.3 3.1 2.4 2 1 0 2 2 2 0 Foie gras liver health family 1 TPR_6 PF13174.1 KFM13512.1 - 0.052 14.0 10.8 2.1 8.9 0.1 5.4 4 1 2 6 6 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFM13512.1 - 0.056 14.1 6.2 0.27 11.9 0.6 3.5 1 1 1 3 3 3 0 Tetratricopeptide repeat AF0941-like PF14591.1 KFM13512.1 - 0.13 12.3 1.9 0.18 11.8 0.4 1.9 2 1 0 2 2 2 0 AF0941-like RPN7 PF10602.4 KFM13512.1 - 0.2 10.9 8.6 0.49 9.7 2.3 2.7 1 1 2 3 3 3 0 26S proteasome subunit RPN7 TPR_1 PF00515.23 KFM13512.1 - 0.35 10.5 18.2 1.6 8.4 0.0 4.7 5 1 0 5 5 4 0 Tetratricopeptide repeat MIT PF04212.13 KFM13512.1 - 1.5 8.7 16.0 24 4.9 0.9 4.8 4 1 2 6 6 6 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 KFM13512.1 - 5.1 6.9 10.4 21 5.0 1.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.7 KFM13512.1 - 5.6 7.7 10.3 2.4 8.9 0.1 4.4 4 1 0 4 4 4 0 Sel1 repeat ELM2 PF01448.19 KFM13513.1 - 2.3e-10 40.9 0.0 6.8e-10 39.4 0.0 1.9 1 0 0 1 1 1 1 ELM2 domain Myb_DNA-binding PF00249.26 KFM13513.1 - 0.0007 19.5 0.1 0.0014 18.6 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain EF-hand_4 PF12763.2 KFM13514.1 - 8.3e-17 60.8 0.0 2.6e-16 59.2 0.0 1.8 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Dynamin_N PF00350.18 KFM13514.1 - 1.9e-14 53.8 0.0 1.1e-11 44.8 0.0 2.2 1 1 0 1 1 1 1 Dynamin family Miro PF08477.8 KFM13514.1 - 0.00012 22.5 0.0 0.0048 17.3 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 KFM13514.1 - 0.00079 18.9 0.0 0.12 11.7 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFM13514.1 - 0.001 19.0 0.0 0.0061 16.4 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_1 PF00036.27 KFM13514.1 - 0.0039 16.3 0.0 0.013 14.7 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 KFM13514.1 - 0.011 15.3 0.7 5.2 6.7 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair Gtr1_RagA PF04670.7 KFM13514.1 - 0.014 14.4 0.0 0.13 11.3 0.0 2.0 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.13 KFM13514.1 - 0.02 14.3 0.0 0.053 12.9 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family MobB PF03205.9 KFM13514.1 - 0.022 14.4 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B EF-hand_5 PF13202.1 KFM13514.1 - 0.05 12.9 0.5 0.2 11.0 0.0 2.2 2 0 0 2 2 2 0 EF hand AAA_22 PF13401.1 KFM13514.1 - 0.052 13.6 1.4 0.16 12.0 0.0 2.4 3 1 0 4 4 3 0 AAA domain AAA_28 PF13521.1 KFM13514.1 - 0.081 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 KFM13514.1 - 0.18 10.7 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 Septin cobW PF02492.14 KFM13514.1 - 0.22 10.9 0.0 15 4.9 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Connexin PF00029.14 KFM13515.1 - 4.3e-36 123.2 2.8 4.3e-36 123.2 2.0 1.6 2 0 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 KFM13515.1 - 5e-21 74.2 0.7 5e-21 74.2 0.5 2.1 2 0 0 2 2 2 1 Gap junction channel protein cysteine-rich domain Histone PF00125.19 KFM13516.1 - 1.7e-33 114.5 0.2 2e-33 114.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KFM13516.1 - 6.2e-05 23.1 0.0 8.2e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 KFM13516.1 - 0.013 14.7 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CBFD_NFYB_HMF PF00808.18 KFM13516.1 - 0.029 14.4 0.0 0.04 13.9 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SPRY PF00622.23 KFM13517.1 - 3.1e-24 85.4 0.4 4e-24 85.0 0.3 1.1 1 0 0 1 1 1 1 SPRY domain PRY PF13765.1 KFM13517.1 - 6.5e-23 80.0 0.9 1e-22 79.3 0.2 1.6 2 0 0 2 2 2 1 SPRY-associated domain TSP_C PF05735.7 KFM13517.1 - 0.0082 15.7 0.0 0.01 15.4 0.0 1.1 1 0 0 1 1 1 1 Thrombospondin C-terminal region GNT-I PF03071.10 KFM13518.1 - 1.4e-153 511.5 0.1 1.6e-153 511.3 0.1 1.0 1 0 0 1 1 1 1 GNT-I family Glyco_tranf_2_3 PF13641.1 KFM13518.1 - 0.00039 20.2 1.1 0.0012 18.7 0.8 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 SPRY PF00622.23 KFM13519.1 - 6.7e-19 68.1 0.1 8.1e-19 67.9 0.1 1.1 1 0 0 1 1 1 1 SPRY domain PRY PF13765.1 KFM13519.1 - 4.4e-17 61.3 0.0 6.9e-17 60.7 0.0 1.3 1 0 0 1 1 1 1 SPRY-associated domain Lectin_C PF00059.16 KFM13520.1 - 3.6e-16 59.7 1.7 6.3e-16 58.9 1.2 1.4 1 0 0 1 1 1 1 Lectin C-type domain Herpes_UL45 PF05473.7 KFM13520.1 - 0.00035 20.0 0.2 0.00059 19.3 0.1 1.4 1 1 0 1 1 1 1 UL45 protein Toxin_13 PF07822.6 KFM13520.1 - 0.059 13.2 0.8 0.19 11.6 0.6 1.9 1 1 0 1 1 1 0 Neurotoxin B-IV-like protein Herpes_UL45 PF05473.7 KFM13521.1 - 0.0046 16.4 0.6 0.006 16.0 0.4 1.2 1 0 0 1 1 1 1 UL45 protein Lectin_C PF00059.16 KFM13522.1 - 1.1e-13 51.6 7.1 1.5e-13 51.2 4.9 1.3 1 0 0 1 1 1 1 Lectin C-type domain Plectin PF00681.15 KFM13523.1 - 5.4e-255 822.8 1.0 8.3e-20 70.0 0.0 24.9 19 6 6 25 25 25 20 Plectin repeat TfuA PF07812.7 KFM13523.1 - 1.1e-06 28.0 0.1 4.4 6.7 0.0 6.4 7 0 0 7 7 7 2 TfuA-like protein HTH_10 PF04967.7 KFM13523.1 - 3.8e-05 23.1 0.0 5.1 6.7 0.0 5.7 5 0 0 5 5 5 2 HTH DNA binding domain Toprim_Crpt PF13342.1 KFM13523.1 - 0.061 12.9 0.3 19 4.9 0.0 3.6 3 0 0 3 3 3 0 C-terminal repeat of topoisomerase Lectin_C PF00059.16 KFM13525.1 - 4.8e-08 33.5 6.6 3.4e-07 30.8 4.6 2.2 1 1 0 1 1 1 1 Lectin C-type domain IncA PF04156.9 KFM13525.1 - 0.0006 19.4 6.3 0.001 18.7 4.4 1.3 1 1 0 1 1 1 1 IncA protein Chordopox_A33R PF05966.7 KFM13525.1 - 0.0016 17.2 2.2 0.0034 16.1 0.3 2.0 2 0 0 2 2 2 1 Chordopoxvirus A33R protein IFT57 PF10498.4 KFM13525.1 - 0.019 13.7 1.5 0.026 13.2 1.0 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Ly49 PF08391.5 KFM13525.1 - 0.022 14.8 0.3 0.055 13.5 0.2 1.7 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region Bestrophin PF01062.16 KFM13525.1 - 0.031 13.2 1.0 0.047 12.6 0.7 1.2 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel Spc7 PF08317.6 KFM13525.1 - 0.036 12.7 3.2 0.064 11.9 2.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Val_tRNA-synt_C PF10458.4 KFM13525.1 - 0.14 12.2 2.6 0.17 12.0 0.2 2.1 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm FliJ PF02050.11 KFM13525.1 - 0.15 12.0 8.6 0.75 9.8 3.8 2.3 1 1 1 2 2 2 0 Flagellar FliJ protein Cast PF10174.4 KFM13525.1 - 0.21 9.5 8.4 0.3 9.0 5.8 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone HR1 PF02185.11 KFM13525.1 - 0.32 10.7 4.0 2.9 7.6 0.2 2.5 1 1 1 2 2 2 0 Hr1 repeat BRE1 PF08647.6 KFM13525.1 - 1.8 8.5 7.9 0.53 10.2 3.1 1.9 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Pkinase_Tyr PF07714.12 KFM13526.1 - 1.4e-36 125.9 0.0 1.8e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM13526.1 - 1.5e-35 122.6 0.0 2.1e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KFM13526.1 - 0.0078 15.2 0.0 0.021 13.8 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Hjc PF01870.13 KFM13526.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Archaeal holliday junction resolvase (hjc) Y_phosphatase PF00102.22 KFM13527.1 - 6.8e-17 61.5 0.1 7.3e-17 61.4 0.1 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFM13527.1 - 1e-05 25.0 0.1 1.3e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFM13528.1 - 1.2e-104 348.8 0.1 1.9e-85 285.9 0.0 2.1 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.15 KFM13528.1 - 4.4e-06 26.3 0.0 9.3e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFM13528.1 - 0.0011 19.2 0.0 0.0022 18.2 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Gly_kinase PF02595.10 KFM13528.1 - 0.012 14.3 0.0 0.44 9.2 0.0 2.1 2 0 0 2 2 2 0 Glycerate kinase family PTPlike_phytase PF14566.1 KFM13528.1 - 0.2 11.6 1.4 0.23 11.5 0.0 1.9 2 0 0 2 2 2 0 Inositol hexakisphosphate RUN PF02759.14 KFM13529.1 - 2.7e-19 69.2 0.1 5.9e-19 68.1 0.1 1.6 1 0 0 1 1 1 1 RUN domain SH3_9 PF14604.1 KFM13529.1 - 2.7e-11 42.8 0.0 8.4e-11 41.2 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 KFM13529.1 - 2.9e-08 32.9 0.6 4.9e-08 32.2 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 KFM13529.1 - 4.4e-08 32.4 0.5 4.9e-07 29.1 0.0 2.5 2 0 0 2 2 2 1 Variant SH3 domain HAD PF12710.2 KFM13530.1 - 2.4e-15 57.1 0.3 2.4e-15 57.1 0.2 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KFM13530.1 - 3.2e-15 55.8 0.0 6.9e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KFM13530.1 - 2.5e-12 47.6 0.1 7.8e-05 23.1 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFM13530.1 - 3.2e-10 39.8 0.0 1.4e-09 37.7 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFM13530.1 - 0.00028 20.5 0.0 0.0011 18.6 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KFM13530.1 - 0.0032 17.6 0.0 0.0067 16.6 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase C2 PF00168.25 KFM13531.1 - 1.5e-06 27.9 0.2 2.2e-06 27.4 0.1 1.2 1 0 0 1 1 1 1 C2 domain nlz1 PF12402.3 KFM13532.1 - 0.11 12.8 1.3 0.27 11.5 0.9 1.7 1 0 0 1 1 1 0 NocA-like zinc-finger protein 1 DUF4210 PF13915.1 KFM13533.1 - 1.6e-21 76.3 0.1 3.7e-21 75.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 KFM13533.1 - 4.9e-17 61.5 0.6 1.2e-16 60.2 0.4 1.8 2 0 0 2 2 2 1 Chromosome segregation during meiosis Band_7 PF01145.20 KFM13534.1 - 2.8e-31 108.8 6.0 1.1e-30 106.9 3.9 2.0 1 1 1 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 KFM13534.1 - 0.037 13.5 0.0 0.079 12.4 0.0 1.6 1 1 0 1 1 1 0 SPFH domain-Band 7 family Phosphodiest PF01663.17 KFM13535.1 - 2.6e-13 50.0 0.0 4.5e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 KFM13535.1 - 0.00039 19.8 1.3 0.00093 18.6 0.9 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily P5-ATPase PF12409.3 KFM13535.1 - 1.9 8.3 3.6 1.3 8.9 0.2 2.4 2 0 0 2 2 2 0 P5-type ATPase cation transporter TPR_11 PF13414.1 KFM13536.1 - 2.2e-20 72.0 9.2 2.8e-07 30.0 0.1 5.3 4 1 1 5 5 5 4 TPR repeat TPR_2 PF07719.12 KFM13536.1 - 1.8e-14 52.4 17.3 0.15 12.0 0.0 8.4 9 1 1 10 10 10 5 Tetratricopeptide repeat TPR_1 PF00515.23 KFM13536.1 - 2.7e-14 52.0 2.9 0.0024 17.4 0.0 7.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFM13536.1 - 6e-12 45.7 13.0 0.0023 18.2 0.2 5.7 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFM13536.1 - 4.8e-11 43.0 33.0 0.00018 22.0 0.7 6.5 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFM13536.1 - 8.8e-11 41.5 15.2 0.00024 20.9 0.5 7.2 5 2 1 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 KFM13536.1 - 2.7e-06 27.4 5.5 1.8 8.7 1.0 4.7 4 0 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 KFM13536.1 - 7.6e-06 26.1 31.1 0.17 12.6 0.0 9.0 7 3 2 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFM13536.1 - 4e-05 23.0 0.0 13 5.8 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat BTAD PF03704.12 KFM13536.1 - 0.0006 20.1 0.3 0.0006 20.1 0.2 4.3 4 2 0 4 4 4 1 Bacterial transcriptional activator domain TPR_7 PF13176.1 KFM13536.1 - 0.0017 18.0 17.8 0.6 10.0 0.0 8.0 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFM13536.1 - 0.013 15.9 13.3 22 5.7 0.0 7.2 7 1 1 8 8 7 0 Tetratricopeptide repeat TPR_4 PF07721.9 KFM13536.1 - 0.11 12.9 31.8 2.7 8.6 0.1 8.4 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_17 PF13431.1 KFM13536.1 - 0.65 10.3 3.9 38 4.8 0.0 5.0 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 KFM13536.1 - 0.81 9.5 12.0 7.7 6.4 0.1 5.0 4 2 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 KFM13536.1 - 3 8.0 9.1 3.6 7.7 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DnaJ PF00226.26 KFM13537.1 - 5.5e-30 102.9 4.4 8.7e-30 102.2 3.0 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KFM13537.1 - 1.5e-24 85.6 0.9 2.4e-22 78.6 0.0 2.5 3 0 0 3 3 3 2 DnaJ C terminal domain EF-hand_1 PF00036.27 KFM13538.1 - 0.19 11.1 0.2 0.75 9.2 0.0 2.0 2 0 0 2 2 2 0 EF hand IL8 PF00048.15 KFM13539.1 - 4.2e-18 65.0 0.1 4.8e-18 64.8 0.0 1.0 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like Ig_2 PF13895.1 KFM13540.1 - 1.9e-05 24.6 0.2 0.00016 21.7 0.0 2.3 3 0 0 3 3 3 1 Immunoglobulin domain ig PF00047.20 KFM13540.1 - 0.0013 18.7 0.1 0.046 13.8 0.0 2.8 2 0 0 2 2 2 1 Immunoglobulin domain EpoR_lig-bind PF09067.5 KFM13540.1 - 0.018 15.0 0.1 0.035 14.1 0.1 1.4 1 0 0 1 1 1 0 Erythropoietin receptor, ligand binding Ig_3 PF13927.1 KFM13540.1 - 0.084 13.3 1.0 1 9.9 0.0 2.9 3 0 0 3 3 3 0 Immunoglobulin domain fn3 PF00041.16 KFM13541.1 - 7.8e-08 32.3 1.2 5.5e-07 29.6 0.1 2.6 2 1 0 2 2 2 1 Fibronectin type III domain Ig_2 PF13895.1 KFM13541.1 - 5e-06 26.5 0.8 2e-05 24.6 0.1 2.3 1 1 0 2 2 2 1 Immunoglobulin domain ig PF00047.20 KFM13541.1 - 0.011 15.8 4.7 0.017 15.2 0.1 2.6 2 1 0 2 2 2 0 Immunoglobulin domain I-set PF07679.11 KFM13541.1 - 0.023 14.5 0.4 0.31 10.9 0.1 2.7 2 0 0 2 2 2 0 Immunoglobulin I-set domain PKD PF00801.15 KFM13541.1 - 0.034 13.8 0.9 0.11 12.2 0.0 2.4 3 0 0 3 3 3 0 PKD domain GalP_UDP_transf PF01087.17 KFM13542.1 - 4e-65 219.3 0.0 5.3e-65 218.9 0.0 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 KFM13542.1 - 6e-53 178.8 0.1 1.3e-52 177.7 0.1 1.5 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 KFM13542.1 - 0.018 15.5 0.0 0.094 13.2 0.0 2.0 2 0 0 2 2 2 0 HIT domain ERG2_Sigma1R PF04622.7 KFM13543.1 - 7.3e-69 231.3 1.7 8.5e-69 231.0 1.2 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein ARID PF01388.16 KFM13544.1 - 4.2e-28 97.0 0.0 7e-28 96.3 0.0 1.4 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain ketoacyl-synt PF00109.21 KFM13544.1 - 0.012 15.1 0.1 0.019 14.4 0.1 1.3 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain DUF3416 PF11896.3 KFM13544.1 - 0.048 13.5 0.8 0.075 12.9 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3416) Dynactin_p22 PF07426.6 KFM13545.1 - 8.2e-61 204.3 7.6 9.1e-61 204.1 5.2 1.0 1 0 0 1 1 1 1 Dynactin subunit p22 BCDHK_Adom3 PF10436.4 KFM13545.1 - 0.13 11.7 1.9 0.18 11.2 1.3 1.3 1 1 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Ofd1_CTDD PF10637.4 KFM13545.1 - 0.15 11.1 1.7 0.23 10.5 1.1 1.4 1 1 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term DUF2661 PF10860.3 KFM13545.1 - 0.19 11.8 0.9 1.1 9.4 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2661) Alba PF01918.16 KFM13546.1 - 1.3e-14 53.5 1.0 1.7e-14 53.1 0.7 1.2 1 0 0 1 1 1 1 Alba WD40 PF00400.27 KFM13547.1 - 4.7e-17 61.1 10.3 2.1e-06 27.4 1.1 6.4 6 1 1 7 7 7 4 WD domain, G-beta repeat DUF4191 PF13829.1 KFM13547.1 - 0.024 13.7 0.0 0.044 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Wbp11 PF09429.5 KFM13547.1 - 1.2 9.1 14.4 0.15 12.0 5.8 2.3 2 0 0 2 2 2 0 WW domain binding protein 11 FAM219A PF15260.1 KFM13548.1 - 1.6e-51 173.8 3.6 2.1e-51 173.4 2.5 1.1 1 0 0 1 1 1 1 Protein family FAM219A KGG PF10685.4 KFM13548.1 - 0.13 12.2 0.5 0.23 11.4 0.4 1.4 1 0 0 1 1 1 0 Stress-induced bacterial acidophilic repeat motif SMRP1 PF15181.1 KFM13549.1 - 7.9e-98 326.9 10.5 8.8e-98 326.8 7.3 1.0 1 0 0 1 1 1 1 Spermatid-specific manchette-related protein 1 Glyco_hydro_31 PF01055.21 KFM13550.1 - 1e-66 225.6 1.8 3.5e-64 217.2 1.2 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Melibiase PF02065.13 KFM13550.1 - 0.0018 17.0 0.2 0.0045 15.7 0.2 1.6 1 1 0 1 1 1 1 Melibiase Glyco_hydro_31 PF01055.21 KFM13552.1 - 8.5e-66 222.5 2.3 2.9e-63 214.2 1.6 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Melibiase PF02065.13 KFM13552.1 - 0.00099 17.8 0.3 0.0024 16.6 0.2 1.5 1 1 0 1 1 1 1 Melibiase Ricin_B_lectin PF00652.17 KFM13554.1 - 8.7e-13 48.3 7.9 3.5e-10 39.9 2.5 1.7 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.9 KFM13554.1 - 2e-05 23.9 0.3 3.9e-05 23.0 0.2 1.5 1 1 0 1 1 1 1 Cytolethal distending toxin A/C family RicinB_lectin_2 PF14200.1 KFM13554.1 - 0.00017 21.8 4.0 0.024 15.0 0.3 2.2 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like DUF2873 PF11395.3 KFM13555.1 - 0.15 11.6 1.0 0.17 11.4 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2873) NUDIX PF00293.23 KFM13556.1 - 2.4e-19 69.2 0.1 2.9e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain I-set PF07679.11 KFM13556.1 - 0.054 13.3 0.0 0.081 12.7 0.0 1.4 1 1 0 1 1 1 0 Immunoglobulin I-set domain RRM_1 PF00076.17 KFM13557.1 - 9e-90 294.3 2.3 1.7e-24 85.2 0.2 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM13557.1 - 3.6e-60 199.8 0.7 3.5e-16 58.9 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM13557.1 - 1.8e-43 146.1 1.4 2.9e-10 39.8 0.0 5.0 6 0 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 KFM13557.1 - 1.7e-31 107.6 0.2 1.3e-30 104.8 0.1 2.3 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.3 KFM13557.1 - 5.9e-09 35.5 1.6 0.03 14.0 0.0 4.4 4 0 0 4 4 4 2 Limkain b1 Nup35_RRM_2 PF14605.1 KFM13557.1 - 2.5e-05 23.9 0.0 3.9 7.3 0.0 4.2 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KFM13557.1 - 7.6e-05 22.5 10.1 0.066 13.0 0.5 4.2 5 0 0 5 5 5 2 RNA binding motif OB_RNB PF08206.6 KFM13557.1 - 0.0019 17.6 3.8 4.1 6.9 0.1 3.6 3 0 0 3 3 3 1 Ribonuclease B OB domain CbiG_mid PF11761.3 KFM13557.1 - 0.0091 16.2 2.7 0.98 9.7 0.0 4.5 6 0 0 6 6 6 1 Cobalamin biosynthesis central region DUF3484 PF11983.3 KFM13557.1 - 1 10.2 4.4 0.65 10.8 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3484) RRM_1 PF00076.17 KFM13558.1 - 6.2e-90 294.8 2.7 9.9e-25 85.9 0.2 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM13558.1 - 1.6e-60 201.0 0.7 1.5e-16 60.1 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM13558.1 - 2.4e-43 145.7 1.6 2.9e-10 39.8 0.0 5.0 6 0 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 KFM13558.1 - 1.7e-31 107.7 0.2 1.3e-30 104.8 0.1 2.3 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.3 KFM13558.1 - 5.6e-09 35.6 2.1 0.032 13.9 0.0 4.4 4 0 0 4 4 4 2 Limkain b1 Nup35_RRM_2 PF14605.1 KFM13558.1 - 2.5e-05 23.9 0.0 3.9 7.3 0.0 4.2 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KFM13558.1 - 6.7e-05 22.6 10.7 0.047 13.5 0.6 4.2 5 0 0 5 5 5 2 RNA binding motif OB_RNB PF08206.6 KFM13558.1 - 0.0017 17.7 3.7 3.9 7.0 0.1 3.6 3 0 0 3 3 3 1 Ribonuclease B OB domain CbiG_mid PF11761.3 KFM13558.1 - 0.0083 16.3 3.1 0.98 9.7 0.0 4.5 6 0 0 6 6 6 1 Cobalamin biosynthesis central region ATP-grasp_2 PF08442.5 KFM13558.1 - 0.024 14.0 0.4 2 7.7 0.1 2.6 3 0 0 3 3 3 0 ATP-grasp domain DUF3484 PF11983.3 KFM13558.1 - 0.98 10.2 4.4 0.65 10.8 0.1 3.0 3 0 0 3 3 2 0 Domain of unknown function (DUF3484) COX7C PF02935.11 KFM13559.1 - 6.8e-20 70.6 0.2 7.2e-20 70.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc RasGAP PF00616.14 KFM13560.1 - 1.3e-41 142.5 1.8 1.8e-41 142.0 0.6 1.7 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase SH2 PF00017.19 KFM13560.1 - 1.8e-23 82.1 0.1 3.3e-21 74.8 0.0 2.8 2 0 0 2 2 2 1 SH2 domain PH PF00169.24 KFM13560.1 - 1.5e-16 60.4 0.1 6.5e-16 58.4 0.0 2.1 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.23 KFM13560.1 - 4.1e-10 38.8 0.0 8.8e-10 37.8 0.0 1.6 1 0 0 1 1 1 1 SH3 domain C2 PF00168.25 KFM13560.1 - 9.7e-09 34.9 0.1 3.4e-08 33.2 0.1 1.9 2 0 0 2 2 2 1 C2 domain SH3_9 PF14604.1 KFM13560.1 - 1.1e-06 28.0 0.0 2.4e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.1 KFM13560.1 - 5.2e-05 23.4 0.4 0.00068 19.8 0.1 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain Cyclin_N PF00134.18 KFM13561.1 - 8.8e-10 38.2 0.1 1.7e-09 37.3 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFM13561.1 - 0.013 15.4 1.5 0.13 12.2 0.4 2.4 2 1 0 2 2 2 0 Cyclin, C-terminal domain SRF-TF PF00319.13 KFM13562.1 - 7.2e-19 66.7 0.3 1.2e-18 66.0 0.2 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) HJURP_C PF12347.3 KFM13562.1 - 8.6e-14 50.8 0.0 2.5e-13 49.3 0.0 1.8 1 0 0 1 1 1 1 Holliday junction regulator protein family C-terminal repeat EF-hand_1 PF00036.27 KFM13563.1 - 6.9e-27 90.6 16.6 9.4e-09 33.9 1.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KFM13563.1 - 3.4e-24 84.7 11.0 5.8e-14 51.9 1.8 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KFM13563.1 - 2.1e-23 80.0 13.3 2.9e-06 26.6 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 KFM13563.1 - 8.3e-17 60.5 15.7 5.7e-12 45.0 0.3 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 KFM13563.1 - 7.1e-15 53.5 16.5 6.7e-05 22.0 0.9 4.6 4 1 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 KFM13563.1 - 8.2e-09 35.2 0.3 0.00029 20.6 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KFM13563.1 - 0.00017 21.2 5.8 0.053 13.2 0.2 2.7 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand UPF0231 PF06062.6 KFM13563.1 - 0.023 14.6 2.5 0.03 14.2 0.5 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0231) SPARC_Ca_bdg PF10591.4 KFM13563.1 - 0.043 13.8 4.6 0.56 10.2 0.8 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region MgtE_N PF03448.12 KFM13563.1 - 0.044 14.0 0.7 0.044 14.0 0.5 2.5 1 1 0 2 2 2 0 MgtE intracellular N domain Caleosin PF05042.8 KFM13563.1 - 0.09 12.3 0.2 1.3 8.5 0.0 2.5 1 1 3 4 4 4 0 Caleosin related protein DUF4373 PF14297.1 KFM13563.1 - 0.25 11.6 2.2 15 5.9 0.1 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4373) RNA_pol_3_Rpc31 PF11705.3 KFM13564.1 - 4e-31 108.7 23.2 4.7e-31 108.5 16.1 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Daxx PF03344.10 KFM13564.1 - 0.029 12.8 26.6 0.036 12.5 18.4 1.0 1 0 0 1 1 1 0 Daxx Family BUD22 PF09073.5 KFM13564.1 - 0.055 12.5 23.9 0.068 12.2 16.5 1.1 1 0 0 1 1 1 0 BUD22 Protocadherin PF08374.6 KFM13564.1 - 0.25 10.9 8.8 0.33 10.5 6.1 1.3 1 0 0 1 1 1 0 Protocadherin BTV_NS2 PF04514.7 KFM13564.1 - 3.4 6.4 18.5 4.6 6.0 12.8 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 PA26 PF04636.8 KFM13564.1 - 3.6 6.1 7.6 5 5.6 5.3 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CobT PF06213.7 KFM13564.1 - 5.7 5.9 22.5 6.8 5.7 15.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT YqhR PF11085.3 KFM13565.1 - 0.019 14.5 0.2 0.027 14.0 0.2 1.2 1 0 0 1 1 1 0 Conserved membrane protein YqhR DUF4199 PF13858.1 KFM13565.1 - 0.066 13.1 0.0 0.09 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Arrestin_N PF00339.24 KFM13566.1 - 1.7e-35 122.0 0.1 1.2e-34 119.2 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KFM13566.1 - 2.2e-23 82.8 0.0 3.9e-19 69.0 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Vps26 PF03643.10 KFM13566.1 - 0.0013 17.5 0.1 0.013 14.3 0.0 2.1 1 1 1 2 2 2 1 Vacuolar protein sorting-associated protein 26 zf-C4 PF00105.13 KFM13568.1 - 2.8e-31 107.5 17.1 4e-31 107.0 11.9 1.2 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 KFM13568.1 - 1e-13 50.8 0.0 1.6e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Arb2 PF09757.4 KFM13570.1 - 4.2e-35 120.7 0.3 5.1e-34 117.2 0.0 2.3 2 0 0 2 2 2 1 Arb2 domain Abhydrolase_6 PF12697.2 KFM13570.1 - 0.00024 21.0 0.0 0.00086 19.2 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFM13570.1 - 0.004 16.9 0.0 0.0075 16.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFM13570.1 - 0.061 12.8 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2674 PF10879.3 KFM13570.1 - 0.063 13.0 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2674) Synaphin PF05835.7 KFM13570.1 - 0.37 10.9 7.9 0.75 9.9 5.5 1.4 1 0 0 1 1 1 0 Synaphin protein BRCT PF00533.21 KFM13571.1 - 0.00026 21.0 0.2 0.0036 17.4 0.1 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KFM13571.1 - 0.074 12.9 0.0 0.21 11.4 0.0 1.8 2 0 0 2 2 2 0 twin BRCT domain Ank_2 PF12796.2 KFM13572.1 - 1.4e-17 63.8 0.1 3.4e-10 40.1 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFM13572.1 - 1.2e-16 59.6 0.7 5.5e-06 25.9 0.1 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 KFM13572.1 - 8.9e-15 54.3 0.0 2.1e-06 27.7 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFM13572.1 - 2.6e-14 53.2 0.1 3.8e-07 30.4 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM13572.1 - 5.7e-14 50.8 0.2 0.00035 20.5 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat COG5 PF10392.4 KFM13573.1 - 0.007 16.3 15.2 0.025 14.5 0.1 3.4 2 2 1 3 3 3 1 Golgi transport complex subunit 5 Lambda_CIII PF02061.11 KFM13573.1 - 0.013 15.4 0.1 0.033 14.1 0.1 1.6 1 0 0 1 1 1 0 Lambda Phage CIII LPP PF04728.8 KFM13573.1 - 0.054 13.2 1.9 0.43 10.4 0.1 3.1 4 0 0 4 4 4 0 Lipoprotein leucine-zipper Baculo_PEP_C PF04513.7 KFM13573.1 - 0.087 12.6 8.0 3.2 7.5 0.4 3.3 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 KFM13573.1 - 1.5 8.6 12.4 9.7 6.0 0.2 3.6 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) ALMT PF11744.3 KFM13573.1 - 5.7 5.4 8.5 3.3 6.2 2.8 2.2 1 1 1 2 2 2 0 Aluminium activated malate transporter TPR_11 PF13414.1 KFM13574.1 - 1.3e-67 223.3 76.3 5.2e-11 42.0 0.1 19.0 13 6 7 20 20 20 16 TPR repeat TPR_16 PF13432.1 KFM13574.1 - 7.4e-45 150.7 27.7 6.4e-08 33.0 0.1 14.8 11 3 4 17 17 15 10 Tetratricopeptide repeat TPR_1 PF00515.23 KFM13574.1 - 4.5e-44 146.3 75.3 7.3e-05 22.2 0.3 24.4 26 2 1 28 28 25 10 Tetratricopeptide repeat TPR_19 PF14559.1 KFM13574.1 - 9e-41 138.0 50.5 0.00063 20.0 2.7 16.9 14 3 3 19 19 16 11 Tetratricopeptide repeat TPR_2 PF07719.12 KFM13574.1 - 1.9e-40 133.5 84.8 0.00047 19.8 0.3 26.2 26 2 0 27 27 26 10 Tetratricopeptide repeat TPR_14 PF13428.1 KFM13574.1 - 2.5e-38 127.0 43.0 0.0002 21.7 0.5 22.2 15 6 8 23 23 20 8 Tetratricopeptide repeat TPR_12 PF13424.1 KFM13574.1 - 1.4e-31 108.2 68.8 3.9e-05 23.5 0.3 16.2 10 4 9 20 20 20 12 Tetratricopeptide repeat TPR_17 PF13431.1 KFM13574.1 - 3.1e-30 101.8 50.9 0.0012 18.8 0.1 21.0 20 2 1 21 21 20 6 Tetratricopeptide repeat TPR_8 PF13181.1 KFM13574.1 - 1.1e-24 84.2 61.6 0.0044 16.7 0.0 20.1 19 2 2 21 21 20 7 Tetratricopeptide repeat TPR_7 PF13176.1 KFM13574.1 - 2.6e-15 54.9 37.1 0.24 11.3 0.0 17.4 19 1 0 19 19 18 4 Tetratricopeptide repeat TPR_9 PF13371.1 KFM13574.1 - 6e-13 48.4 12.5 0.008 16.0 0.0 9.1 10 1 1 11 11 9 4 Tetratricopeptide repeat Apc3 PF12895.2 KFM13574.1 - 6.9e-12 45.3 44.3 0.014 15.5 0.2 10.8 9 1 1 10 10 10 7 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 KFM13574.1 - 2.3e-08 33.4 52.0 2.4e-06 26.8 0.6 8.6 7 3 1 9 9 9 3 Tetratricopeptide repeat TPR_6 PF13174.1 KFM13574.1 - 1.7e-06 28.0 55.9 0.99 10.0 0.1 17.3 20 0 0 20 20 16 3 Tetratricopeptide repeat TPR_21 PF09976.4 KFM13574.1 - 0.0036 17.2 43.4 0.14 12.1 0.4 9.1 8 2 0 10 10 10 3 Tetratricopeptide repeat BTAD PF03704.12 KFM13574.1 - 0.016 15.5 0.1 0.016 15.5 0.0 5.3 6 0 0 6 6 6 0 Bacterial transcriptional activator domain TPR_20 PF14561.1 KFM13574.1 - 0.017 15.1 19.1 0.28 11.3 0.0 8.9 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_4 PF07721.9 KFM13574.1 - 0.083 13.3 4.3 5.5 7.7 0.0 5.0 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 KFM13574.1 - 0.12 12.3 21.0 8.7 6.4 0.0 9.9 12 0 0 12 12 10 0 Tetratricopeptide repeat DUF982 PF06169.7 KFM13574.1 - 0.13 11.9 1.8 1.3 8.8 0.1 3.8 3 1 1 4 4 3 0 Protein of unknown function (DUF982) Sulfatase PF00884.18 KFM13575.1 - 2.8e-43 148.2 0.1 5.1e-43 147.4 0.1 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 KFM13575.1 - 9.3e-07 28.4 0.0 1.4e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF229 PF02995.12 KFM13575.1 - 1.1e-05 24.1 0.1 8e-05 21.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Phosphodiest PF01663.17 KFM13575.1 - 0.00029 20.2 0.0 0.00067 19.0 0.0 1.6 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.7 KFM13575.1 - 0.022 13.5 0.0 0.032 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF4572 PF15139.1 KFM13575.1 - 0.16 11.8 1.3 1.5 8.5 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4572) Rieske_2 PF13806.1 KFM13576.1 - 3.3e-10 39.5 0.0 4.4e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.21 KFM13576.1 - 7e-05 22.3 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain BTB PF00651.26 KFM13577.1 - 1.5e-24 86.1 3.4 2.5e-18 66.0 0.3 3.5 3 0 0 3 3 3 2 BTB/POZ domain Ras PF00071.17 KFM13577.1 - 3.5e-06 26.5 0.0 7.4e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM13577.1 - 0.031 14.7 0.1 0.26 11.7 0.0 2.3 2 0 0 2 2 2 0 Miro-like protein S1 PF00575.18 KFM13579.1 - 1.5e-08 34.5 0.0 2.8e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain zf-CCHC_3 PF13917.1 KFM13579.1 - 0.00046 19.8 0.8 0.00079 19.1 0.6 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 KFM13579.1 - 0.03 13.8 0.7 0.06 12.8 0.5 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger CHORD PF04968.7 KFM13579.1 - 0.038 14.2 1.5 3.8 7.8 0.0 2.4 2 0 0 2 2 2 0 CHORD zf-CCHC PF00098.18 KFM13579.1 - 0.04 13.8 6.0 0.088 12.7 4.1 1.6 1 0 0 1 1 1 0 Zinc knuckle CpXC PF14353.1 KFM13579.1 - 0.057 13.3 0.5 0.16 11.9 0.2 1.7 1 1 1 2 2 2 0 CpXC protein Toxin_14 PF07829.6 KFM13579.1 - 0.41 10.4 3.2 16 5.3 0.5 2.3 2 0 0 2 2 2 0 Alpha-A conotoxin PIVA-like protein zf-CCHC_4 PF14392.1 KFM13579.1 - 0.6 9.8 4.0 1.7 8.3 2.8 1.7 1 0 0 1 1 1 0 Zinc knuckle WD40 PF00400.27 KFM13580.1 - 3e-65 213.9 5.0 6.1e-11 41.7 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KFM13580.1 - 4.8e-09 36.1 0.3 0.0061 16.2 0.1 3.1 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 KFM13580.1 - 0.00029 19.2 0.1 0.45 8.7 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.3 KFM13580.1 - 0.0041 15.3 5.9 1.3 7.1 0.0 3.9 1 1 2 3 3 3 2 Nucleoporin Nup120/160 PD40 PF07676.7 KFM13580.1 - 0.067 12.8 0.0 0.53 10.0 0.1 2.3 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat NKAIN PF05640.9 KFM13581.1 - 2.4e-84 281.2 7.4 2.7e-84 281.1 5.1 1.0 1 0 0 1 1 1 1 Na,K-Atpase Interacting protein PUF PF00806.14 KFM13582.1 - 1.2e-73 238.5 8.3 4.7e-09 35.2 0.1 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.6 KFM13582.1 - 0.96 9.2 5.5 2.9 7.7 0.0 3.6 3 1 1 4 4 4 0 CPL (NUC119) domain Syndecan PF01034.15 KFM13583.1 - 1.2e-32 111.3 0.2 1.8e-32 110.7 0.1 1.3 1 0 0 1 1 1 1 Syndecan domain TFIIA PF03153.8 KFM13583.1 - 7.1 6.4 8.2 12 5.7 5.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mtp PF03821.11 KFM13585.1 - 4.2e-72 242.3 15.2 4.7e-72 242.1 10.5 1.0 1 0 0 1 1 1 1 Golgi 4-transmembrane spanning transporter CybS PF05328.7 KFM13585.1 - 0.4 10.2 3.3 3.7 7.1 0.3 2.5 1 1 0 2 2 2 0 CybS ABC2_membrane_2 PF12679.2 KFM13585.1 - 1.3 7.7 9.6 1.9 7.2 6.6 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein VWA PF00092.23 KFM13586.1 - 1.7e-98 327.6 4.5 2.6e-50 170.5 0.3 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.1 KFM13586.1 - 2.5e-33 115.6 0.1 1.4e-15 57.8 0.0 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_3 PF13768.1 KFM13586.1 - 1.9e-14 53.6 0.0 1.1e-06 28.4 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain Matrilin_ccoil PF10393.4 KFM13586.1 - 2.3e-12 46.0 1.1 1e-11 44.0 0.8 2.2 1 0 0 1 1 1 1 Trimeric coiled-coil oligomerisation domain of matrilin FXa_inhibition PF14670.1 KFM13586.1 - 8.5e-10 38.5 8.7 8.5e-10 38.5 6.0 1.9 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site cEGF PF12662.2 KFM13586.1 - 1e-05 25.0 1.0 1e-05 25.0 0.7 2.2 2 0 0 2 2 2 1 Complement Clr-like EGF-like EGF_CA PF07645.10 KFM13586.1 - 1.2e-05 25.2 7.3 1.2e-05 25.2 5.0 2.1 2 0 0 2 2 2 1 Calcium-binding EGF domain EGF PF00008.22 KFM13586.1 - 0.0011 18.8 4.9 0.0011 18.8 3.4 2.5 3 0 0 3 3 3 1 EGF-like domain DUF2242 PF10001.4 KFM13586.1 - 0.07 13.0 1.1 6 6.7 0.0 3.4 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2242) Y_phosphatase PF00102.22 KFM13587.1 - 1.4e-139 463.0 0.5 5.7e-80 268.0 0.1 2.5 2 0 0 2 2 2 2 Protein-tyrosine phosphatase MAM PF00629.18 KFM13587.1 - 1e-37 129.3 0.0 2.2e-37 128.2 0.0 1.6 1 0 0 1 1 1 1 MAM domain fn3 PF00041.16 KFM13587.1 - 5.2e-30 103.4 0.8 1.5e-11 44.2 0.0 4.9 5 0 0 5 5 5 3 Fibronectin type III domain DSPc PF00782.15 KFM13587.1 - 1.2e-06 28.1 0.9 0.03 13.8 0.0 2.5 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFM13587.1 - 3.3e-05 24.1 0.2 0.06 13.5 0.0 2.6 2 0 0 2 2 2 2 Tyrosine phosphatase family Ig_2 PF13895.1 KFM13587.1 - 5.1e-05 23.3 0.0 0.00016 21.6 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain PTPlike_phytase PF14566.1 KFM13587.1 - 0.00012 22.1 0.1 0.12 12.4 0.0 2.5 2 0 0 2 2 2 2 Inositol hexakisphosphate I-set PF07679.11 KFM13587.1 - 0.017 14.9 0.0 0.042 13.7 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin I-set domain ADH_zinc_N PF00107.21 KFM13588.1 - 9.2e-19 67.2 0.0 1.4e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFM13588.1 - 7.3e-11 41.7 0.0 1.7e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KFM13588.1 - 1.2e-06 29.4 0.0 2.7e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase GDPD_2 PF13653.1 KFM13588.1 - 0.067 13.4 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family RRM_1 PF00076.17 KFM13589.1 - 2.7e-22 78.1 0.0 2.7e-14 52.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM13589.1 - 4e-12 45.9 0.0 1.7e-08 34.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM13589.1 - 1.6e-10 40.6 0.0 9.4e-05 22.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MBT PF02820.13 KFM13591.1 - 8.5e-94 307.5 1.3 1.1e-31 108.5 0.0 3.2 3 0 0 3 3 3 3 mbt repeat zf-C2HC PF01530.13 KFM13591.1 - 4.6e-13 48.6 10.0 9.1e-13 47.6 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C2HC type Glyco_hydro_2_N PF02837.13 KFM13591.1 - 0.001 18.6 0.1 1.6 8.2 0.0 2.8 3 0 0 3 3 3 2 Glycosyl hydrolases family 2, sugar binding domain Tudor-knot PF11717.3 KFM13591.1 - 1.4 8.7 8.1 0.87 9.3 0.6 2.9 3 0 0 3 3 3 0 RNA binding activity-knot of a chromodomain Ninjurin PF04923.7 KFM13592.1 - 4.1e-33 113.2 8.2 4.6e-33 113.0 5.7 1.0 1 0 0 1 1 1 1 Ninjurin DUF1418 PF07214.7 KFM13592.1 - 0.06 12.9 3.2 0.099 12.2 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) RebB PF11747.3 KFM13592.1 - 0.19 11.6 1.1 0.31 10.9 0.7 1.6 1 1 0 1 1 1 0 Killing trait PA14 PF07691.7 KFM13593.1 - 1.4e-24 86.4 0.1 2.4e-24 85.6 0.1 1.4 1 0 0 1 1 1 1 PA14 domain CHGN PF05679.11 KFM13593.1 - 2.8e-16 59.3 0.0 1.2e-15 57.2 0.0 1.9 1 1 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.9 KFM13593.1 - 4.3e-12 45.3 0.9 9.2e-12 44.2 0.6 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFM13593.1 - 0.0069 15.5 0.6 0.46 9.5 0.1 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Atg14 PF10186.4 KFM13594.1 - 0.32 9.9 52.7 0.16 10.9 6.0 3.6 2 1 2 4 4 4 0 UV radiation resistance protein and autophagy-related subunit 14 PLU-1 PF08429.6 KFM13595.1 - 5.6e-99 331.2 27.7 3.2e-98 328.7 9.4 4.0 4 1 0 4 4 4 2 PLU-1-like protein JmjC PF02373.17 KFM13595.1 - 6.9e-46 155.1 1.4 2.3e-45 153.5 0.9 2.0 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 KFM13595.1 - 2.2e-29 100.8 36.7 4.1e-12 45.6 2.3 3.8 3 0 0 3 3 3 3 PHD-finger ARID PF01388.16 KFM13595.1 - 2.7e-24 84.8 0.0 2.7e-24 84.8 0.0 2.5 3 0 0 3 3 3 1 ARID/BRIGHT DNA binding domain zf-C5HC2 PF02928.11 KFM13595.1 - 1.5e-17 63.3 12.4 1.5e-17 63.3 8.6 3.5 3 0 0 3 3 3 1 C5HC2 zinc finger SNF PF00209.13 KFM13596.1 - 3.9e-246 817.5 36.7 4.5e-246 817.3 25.5 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF3671 PF12420.3 KFM13596.1 - 0.31 11.0 15.1 0.097 12.6 0.5 3.7 3 2 1 4 4 4 0 Protein of unknown function SNF PF00209.13 KFM13597.1 - 2.5e-245 814.9 38.0 2.8e-245 814.7 26.3 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.13 KFM13598.1 - 2.1e-228 759.0 39.7 2.4e-228 758.8 27.5 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family TM231 PF10149.4 KFM13598.1 - 0.047 12.6 1.0 0.11 11.5 0.7 1.5 1 0 0 1 1 1 0 Transmembrane protein 231 RhodobacterPufX PF11511.3 KFM13598.1 - 0.22 10.9 3.6 1 8.8 2.5 2.1 1 0 0 1 1 1 0 Intrinsic membrane protein PufX Sec7 PF01369.15 KFM13599.1 - 3e-60 203.1 0.0 7.6e-60 201.8 0.0 1.7 1 0 0 1 1 1 1 Sec7 domain IQ PF00612.22 KFM13599.1 - 0.052 13.2 1.3 0.2 11.3 0.2 2.5 2 0 0 2 2 2 0 IQ calmodulin-binding motif WASH_WAHD PF11945.3 KFM13600.1 - 4.9e-150 498.7 0.3 6.9e-150 498.3 0.2 1.1 1 0 0 1 1 1 1 WAHD domain of WASH complex TIR PF01582.15 KFM13600.1 - 0.066 12.6 0.1 0.14 11.6 0.1 1.6 1 0 0 1 1 1 0 TIR domain Helicase_C_2 PF13307.1 KFM13601.1 - 5.3e-57 192.3 0.0 2.5e-56 190.1 0.0 2.3 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 KFM13601.1 - 1.1e-50 171.4 0.9 2.6e-50 170.2 0.6 1.7 1 0 0 1 1 1 1 DEAD_2 SNF2_N PF00176.18 KFM13601.1 - 0.045 12.5 1.1 0.46 9.2 0.0 2.4 2 0 0 2 2 2 0 SNF2 family N-terminal domain zf-H2C2_2 PF13465.1 KFM13603.1 - 1.6e-65 214.3 59.1 3.3e-11 42.8 0.3 8.7 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.21 KFM13603.1 - 1.2e-58 192.0 58.0 5e-08 32.8 0.7 8.1 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM13603.1 - 2.4e-39 130.7 52.0 6.8e-05 22.9 0.4 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM13603.1 - 8e-32 108.1 45.4 2.6e-05 23.9 0.1 8.2 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM13603.1 - 3.8e-21 74.6 30.7 0.0027 17.7 0.1 8.2 8 0 0 8 8 8 6 Zinc-finger double-stranded RNA-binding Prok-RING_1 PF14446.1 KFM13603.1 - 8.4e-12 44.6 15.2 1.3 8.8 0.0 8.0 8 0 0 8 8 8 1 Prokaryotic RING finger family 1 zf-met PF12874.2 KFM13603.1 - 3.7e-11 42.8 48.3 0.15 12.2 0.1 8.2 8 0 0 8 8 8 6 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 KFM13603.1 - 2e-08 34.0 46.7 0.11 12.4 3.4 7.5 3 3 4 7 7 7 6 Zinc ribbon domain XPA_N PF01286.13 KFM13603.1 - 3.7e-08 32.9 34.1 0.032 13.8 0.2 8.1 8 0 0 8 8 8 3 XPA protein N-terminal Zn_Tnp_IS1595 PF12760.2 KFM13603.1 - 2.4e-07 30.4 41.1 0.098 12.4 1.6 6.3 5 1 1 6 6 6 3 Transposase zinc-ribbon domain LIM PF00412.17 KFM13603.1 - 2.3e-06 27.5 29.3 0.066 13.2 0.4 5.6 3 2 3 6 6 6 3 LIM domain zf-Di19 PF05605.7 KFM13603.1 - 4.7e-05 23.4 32.2 0.016 15.3 1.3 5.4 2 2 3 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding C1_4 PF07975.7 KFM13603.1 - 0.00013 21.8 34.9 1.2 9.1 1.6 6.6 1 1 7 8 8 8 2 TFIIH C1-like domain CpXC PF14353.1 KFM13603.1 - 0.00014 21.8 29.4 4.6 7.2 2.4 7.8 3 2 2 6 6 6 0 CpXC protein DNA_RNApol_7kD PF03604.8 KFM13603.1 - 0.00049 19.4 25.9 5 6.6 0.1 7.8 8 0 0 8 8 8 0 DNA directed RNA polymerase, 7 kDa subunit zf-AN1 PF01428.11 KFM13603.1 - 0.00092 19.0 33.0 12 5.8 0.1 8.1 8 0 0 8 8 8 0 AN1-like Zinc finger Elf1 PF05129.8 KFM13603.1 - 0.0039 16.8 29.5 0.16 11.6 1.4 5.0 1 1 3 4 4 4 2 Transcription elongation factor Elf1 like zf-RING_3 PF14369.1 KFM13603.1 - 0.0053 16.7 26.8 4.4 7.3 0.0 7.9 8 0 0 8 8 8 0 zinc-finger YhfH PF14149.1 KFM13603.1 - 0.0071 16.1 27.0 5.3 6.9 0.2 7.1 7 0 0 7 7 7 0 YhfH-like protein zf-ISL3 PF14690.1 KFM13603.1 - 0.0084 16.1 32.6 7.5 6.6 0.1 8.3 7 1 1 8 8 8 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 TFIIS_C PF01096.13 KFM13603.1 - 0.0089 15.6 38.5 1.1 8.9 0.2 8.0 8 0 0 8 8 8 1 Transcription factor S-II (TFIIS) zf-BED PF02892.10 KFM13603.1 - 0.019 14.7 43.0 0.65 9.8 1.0 7.9 1 1 7 8 8 8 0 BED zinc finger zinc_ribbon_2 PF13240.1 KFM13603.1 - 0.03 13.7 34.4 0.89 9.1 0.1 6.5 5 3 2 7 7 6 0 zinc-ribbon domain zf-trcl PF13451.1 KFM13603.1 - 0.053 13.1 28.6 4 7.1 0.1 7.7 8 0 0 8 8 8 0 Probable zinc-binding domain FYDLN_acid PF09538.5 KFM13603.1 - 0.062 13.8 25.4 19 5.8 1.9 7.0 1 1 4 5 5 5 0 Protein of unknown function (FYDLN_acid) UPF0547 PF10571.4 KFM13603.1 - 0.069 12.8 37.1 0.76 9.5 0.2 7.8 8 0 0 8 8 8 0 Uncharacterised protein family UPF0547 RRN7 PF11781.3 KFM13603.1 - 0.1 12.1 23.5 13 5.4 0.0 7.5 8 0 0 8 8 8 0 RNA polymerase I-specific transcription initiation factor Rrn7 DUF2321 PF10083.4 KFM13603.1 - 0.13 11.7 19.8 0.28 10.6 1.3 4.4 1 1 5 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2321) zinc-ribbons_6 PF07191.7 KFM13603.1 - 0.17 11.7 30.1 4.4 7.1 0.8 6.4 4 4 2 6 6 6 0 zinc-ribbons BolA PF01722.13 KFM13603.1 - 0.17 11.8 15.5 7.9 6.5 0.0 4.7 2 1 3 5 5 5 0 BolA-like protein Zn_ribbon_recom PF13408.1 KFM13603.1 - 0.18 12.0 30.9 29 5.0 2.0 6.0 3 2 1 4 4 4 0 Recombinase zinc beta ribbon domain Rad50_zn_hook PF04423.9 KFM13603.1 - 0.22 11.0 0.1 0.22 11.0 0.0 4.9 6 0 0 6 6 5 0 Rad50 zinc hook motif DUF2072 PF09845.4 KFM13603.1 - 0.22 11.4 0.3 0.22 11.4 0.2 6.9 5 2 3 8 8 8 0 Zn-ribbon containing protein (DUF2072) zf-C2H2_2 PF12756.2 KFM13603.1 - 0.27 11.3 34.1 0.54 10.3 0.6 6.8 1 1 6 7 7 7 0 C2H2 type zinc-finger (2 copies) Yippee-Mis18 PF03226.9 KFM13603.1 - 0.31 11.0 26.7 14 5.8 1.8 6.4 2 2 4 7 7 7 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HNH PF01844.18 KFM13603.1 - 0.36 10.7 29.5 11 6.0 0.2 7.6 8 0 0 8 8 8 0 HNH endonuclease MBD PF01429.14 KFM13603.1 - 0.48 10.0 4.6 46 3.6 3.0 4.2 1 1 1 2 2 2 0 Methyl-CpG binding domain C1_3 PF07649.7 KFM13603.1 - 0.66 10.0 21.0 56 3.8 0.0 7.6 8 0 0 8 8 8 0 C1-like domain PHF5 PF03660.9 KFM13603.1 - 0.68 10.0 15.5 3.6 7.6 0.3 3.9 1 1 3 4 4 4 0 PHF5-like protein zf-ribbon_3 PF13248.1 KFM13603.1 - 0.99 8.7 34.5 2 7.7 0.1 7.5 8 0 0 8 8 8 0 zinc-ribbon domain A2L_zn_ribbon PF08792.5 KFM13603.1 - 1.5 8.3 43.6 0.36 10.3 0.2 8.0 8 0 0 8 8 8 0 A2L zinc ribbon domain zf-C2HC_2 PF13913.1 KFM13603.1 - 1.6 8.4 38.6 0.54 9.9 0.1 7.6 8 0 0 8 8 7 0 zinc-finger of a C2HC-type DUF2688 PF10892.3 KFM13603.1 - 1.6 8.4 25.6 2 8.1 0.1 7.1 7 1 1 8 8 8 0 Protein of unknown function (DUF2688) zf-LYAR PF08790.6 KFM13603.1 - 2.4 7.9 31.6 7.8 6.2 0.3 7.5 8 0 0 8 8 8 0 LYAR-type C2HC zinc finger GF_recep_IV PF14843.1 KFM13603.1 - 2.8 7.5 28.1 0.15 11.6 5.3 3.1 1 1 3 4 4 4 0 Growth factor receptor domain IV GAGA PF09237.6 KFM13603.1 - 4.1 7.0 22.4 3.6 7.2 0.2 5.3 1 1 4 6 6 6 0 GAGA factor zinc_ribbon_5 PF13719.1 KFM13603.1 - 4.5 6.9 38.0 22 4.7 0.0 7.7 5 2 2 7 7 7 0 zinc-ribbon domain Ogr_Delta PF04606.7 KFM13603.1 - 7.1 6.3 39.0 0.25 11.0 0.8 5.7 3 2 1 5 5 5 0 Ogr/Delta-like zinc finger PBP_sp32 PF07222.7 KFM13604.1 - 1.3e-34 119.4 1.3 1.4e-34 119.3 0.9 1.0 1 0 0 1 1 1 1 Proacrosin binding protein sp32 TPR_11 PF13414.1 KFM13605.1 - 3.7e-61 202.6 34.1 9.7e-12 44.3 0.1 8.0 1 1 7 9 9 9 9 TPR repeat TPR_2 PF07719.12 KFM13605.1 - 5.5e-52 169.5 31.1 1e-05 25.0 0.3 11.5 10 1 1 11 11 11 10 Tetratricopeptide repeat TPR_1 PF00515.23 KFM13605.1 - 1.6e-48 160.4 30.6 0.00016 21.1 0.1 11.8 11 1 0 11 11 11 10 Tetratricopeptide repeat TPR_16 PF13432.1 KFM13605.1 - 1.2e-46 156.4 21.9 1.6e-09 38.1 0.6 7.7 5 3 3 8 8 8 8 Tetratricopeptide repeat TPR_12 PF13424.1 KFM13605.1 - 4.7e-45 151.4 28.5 1.2e-10 41.1 0.0 7.3 2 1 6 8 8 8 8 Tetratricopeptide repeat TPR_17 PF13431.1 KFM13605.1 - 1e-42 140.7 22.1 9.4e-06 25.4 0.1 12.0 12 0 0 12 12 12 8 Tetratricopeptide repeat TPR_14 PF13428.1 KFM13605.1 - 3.6e-40 132.7 18.2 2.7e-05 24.4 0.5 11.1 3 2 8 11 11 11 10 Tetratricopeptide repeat TPR_19 PF14559.1 KFM13605.1 - 3.9e-37 126.4 22.1 3.7e-11 43.1 0.3 8.0 4 2 4 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.1 KFM13605.1 - 2.1e-33 111.5 22.3 0.00039 19.9 0.4 11.3 10 1 1 11 11 11 8 Tetratricopeptide repeat DUF1736 PF08409.6 KFM13605.1 - 3.7e-32 109.7 2.7 1.3e-31 108.0 1.9 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_7 PF13176.1 KFM13605.1 - 3.2e-23 79.6 18.3 0.0002 20.8 0.0 10.0 9 1 1 10 10 10 6 Tetratricopeptide repeat TPR_10 PF13374.1 KFM13605.1 - 3e-20 71.4 27.4 0.00036 20.3 0.1 10.7 9 2 1 10 10 10 4 Tetratricopeptide repeat TPR_15 PF13429.1 KFM13605.1 - 2.2e-15 56.4 13.6 9.3e-09 34.7 2.5 5.1 2 2 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFM13605.1 - 8.2e-14 51.0 20.3 0.24 11.9 0.0 10.8 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_9 PF13371.1 KFM13605.1 - 2.4e-12 46.5 9.3 0.013 15.3 0.0 5.8 3 1 4 7 7 7 5 Tetratricopeptide repeat Apc3 PF12895.2 KFM13605.1 - 2.5e-11 43.5 21.3 9.4e-06 25.6 3.1 5.6 2 1 3 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 KFM13605.1 - 7.1e-11 41.4 0.0 0.98 10.0 0.0 7.9 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_5 PF12688.2 KFM13605.1 - 7.3e-07 29.2 10.2 0.018 15.0 0.2 4.7 3 2 2 5 5 4 3 Tetratrico peptide repeat FAT PF02259.18 KFM13605.1 - 6.3e-06 25.4 8.3 0.0022 17.0 0.2 2.8 2 1 0 2 2 2 2 FAT domain NARP1 PF12569.3 KFM13605.1 - 1.3e-05 24.2 7.9 0.017 13.8 0.8 3.8 1 1 3 4 4 4 3 NMDA receptor-regulated protein 1 ChAPs PF09295.5 KFM13605.1 - 0.00017 20.5 0.1 0.0072 15.1 0.1 2.3 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) Apc5 PF12862.2 KFM13605.1 - 0.00031 20.5 3.9 0.47 10.3 0.0 4.4 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 5 TPR_3 PF07720.7 KFM13605.1 - 0.00068 19.3 10.3 0.0036 17.0 0.0 4.8 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_20 PF14561.1 KFM13605.1 - 0.0015 18.6 9.8 2.3 8.3 0.0 5.8 3 2 5 8 8 8 2 Tetratricopeptide repeat SNAP PF14938.1 KFM13605.1 - 0.0026 16.9 12.0 0.035 13.2 2.8 3.8 2 1 0 3 3 3 1 Soluble NSF attachment protein, SNAP BTAD PF03704.12 KFM13605.1 - 0.0042 17.3 11.5 0.16 12.2 3.7 3.3 1 1 1 2 2 2 1 Bacterial transcriptional activator domain PPR PF01535.15 KFM13605.1 - 0.0068 16.3 3.8 8.2 6.6 0.0 5.2 7 0 0 7 7 3 0 PPR repeat Coatomer_E PF04733.9 KFM13605.1 - 0.0073 15.5 6.1 1 8.5 0.0 3.8 2 1 1 4 4 4 1 Coatomer epsilon subunit DUF627 PF04781.7 KFM13605.1 - 0.012 15.1 2.8 7.3 6.2 0.0 4.7 3 2 1 5 5 5 0 Protein of unknown function (DUF627) Sel1 PF08238.7 KFM13605.1 - 0.013 16.1 17.6 0.6 10.8 0.1 7.3 7 1 1 8 8 6 0 Sel1 repeat Alkyl_sulf_dimr PF14863.1 KFM13605.1 - 0.02 15.0 0.5 0.079 13.1 0.4 2.0 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation Mad3_BUB1_I PF08311.7 KFM13605.1 - 0.026 14.3 0.1 0.026 14.3 0.1 3.7 4 2 0 4 4 3 0 Mad3/BUB1 homology region 1 EST1_DNA_bind PF10373.4 KFM13605.1 - 0.028 13.6 9.9 1.4 8.0 0.1 4.9 5 0 0 5 5 5 0 Est1 DNA/RNA binding domain Rapsyn_N PF10579.4 KFM13605.1 - 0.056 13.2 1.6 17 5.3 0.0 3.9 4 0 0 4 4 3 0 Rapsyn N-terminal myristoylation and linker region TPR_21 PF09976.4 KFM13605.1 - 0.085 12.7 14.7 0.86 9.5 0.0 4.4 5 1 0 5 5 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KFM13605.1 - 0.15 11.9 9.9 6.8 6.6 0.2 4.7 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.13 KFM13605.1 - 7.8 6.4 22.5 3.1 7.7 0.3 7.5 8 2 2 10 10 9 0 MIT (microtubule interacting and transport) domain IBN_N PF03810.14 KFM13606.1 - 1.3e-21 76.3 0.3 4e-18 65.1 0.0 4.5 4 0 0 4 4 4 1 Importin-beta N-terminal domain Cse1 PF08506.5 KFM13606.1 - 2.4e-09 36.2 4.0 2.4e-09 36.2 2.8 2.9 2 1 0 3 3 3 1 Cse1 GRP PF07172.6 KFM13606.1 - 0.0022 18.4 3.1 0.005 17.2 2.2 1.5 1 0 0 1 1 1 1 Glycine rich protein family DUF1539 PF07560.6 KFM13606.1 - 0.0064 16.3 1.9 0.2 11.5 0.0 3.2 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1539) HEAT_2 PF13646.1 KFM13606.1 - 0.04 14.1 0.0 12 6.2 0.0 3.8 3 0 0 3 3 3 0 HEAT repeats PPP4R2 PF09184.6 KFM13606.1 - 0.055 13.0 0.1 0.055 13.0 0.0 3.2 3 1 0 3 3 3 0 PPP4R2 Xpo1 PF08389.7 KFM13606.1 - 0.19 11.6 13.1 0.095 12.6 0.4 4.4 4 1 0 4 4 4 0 Exportin 1-like protein TT_ORF2 PF02957.10 KFM13606.1 - 6.7 7.4 9.8 17 6.1 6.8 1.6 1 0 0 1 1 1 0 TT viral ORF2 Caprin-1_C PF12287.3 KFM13607.1 - 1.3e-39 136.4 26.1 2.7e-39 135.4 18.1 1.5 1 0 0 1 1 1 1 Cytoplasmic activation/proliferation-associated protein-1 C term C1q PF00386.16 KFM13607.1 - 1.1e-31 109.4 0.0 2.4e-31 108.3 0.0 1.6 1 0 0 1 1 1 1 C1q domain FAM60A PF15396.1 KFM13608.1 - 2.7e-88 295.2 11.0 3.2e-88 295.0 7.6 1.0 1 0 0 1 1 1 1 Protein Family FAM60A DUF2706 PF10913.3 KFM13608.1 - 0.055 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2706) DENN PF02141.16 KFM13609.1 - 1.4e-62 210.7 5.3 4.4e-62 209.0 2.7 2.3 2 0 0 2 2 2 1 DENN (AEX-3) domain RUN PF02759.14 KFM13609.1 - 7.9e-41 138.9 5.8 6.6e-20 71.2 2.0 3.1 3 0 0 3 3 3 2 RUN domain uDENN PF03456.13 KFM13609.1 - 8.5e-21 73.6 0.3 3.3e-20 71.8 0.0 2.2 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.14 KFM13609.1 - 3.3e-19 68.7 8.5 4e-19 68.4 1.9 3.4 3 1 1 4 4 4 1 dDENN domain PLAT PF01477.18 KFM13609.1 - 8.8e-14 51.8 0.0 1.8e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 PLAT/LH2 domain PrmA PF06325.8 KFM13610.1 - 1.5e-10 40.7 0.1 2.4e-10 40.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 KFM13610.1 - 8.1e-10 38.4 0.0 2.1e-09 37.0 0.0 1.6 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 KFM13610.1 - 7.2e-05 22.8 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFM13610.1 - 0.0011 19.5 0.1 0.0022 18.5 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 KFM13610.1 - 0.0023 17.5 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.9 KFM13610.1 - 0.0043 16.4 0.0 0.0059 16.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.10 KFM13610.1 - 0.023 14.1 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_23 PF13489.1 KFM13610.1 - 0.032 13.9 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain LRR_6 PF13516.1 KFM13611.1 - 4.5e-14 50.9 7.5 0.031 14.3 0.0 6.5 5 1 1 6 6 6 4 Leucine Rich repeat LRR_4 PF12799.2 KFM13611.1 - 0.00023 20.6 8.3 0.0052 16.3 0.7 4.3 4 1 1 5 5 5 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM13611.1 - 0.051 13.6 8.4 36 4.9 0.0 5.6 4 3 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.1 KFM13611.1 - 0.051 13.3 3.5 1.7 8.4 0.4 3.8 3 1 1 4 4 4 0 Leucine rich repeat Pentapeptide_3 PF13576.1 KFM13611.1 - 0.26 11.2 1.3 15 5.5 0.8 3.2 2 1 0 2 2 2 0 Pentapeptide repeats (9 copies) Adeno_E4_34 PF04528.8 KFM13611.1 - 0.67 9.5 8.1 0.23 11.0 0.3 2.5 1 1 0 2 2 2 0 Adenovirus early E4 34 kDa protein conserved region LRR_2 PF07723.8 KFM13611.1 - 1.2 9.7 4.5 38 4.9 0.0 4.1 4 0 0 4 4 4 0 Leucine Rich Repeat DUF4617 PF15395.1 KFM13613.1 - 0 1042.1 107.4 0 1042.1 74.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4617) BicD PF09730.4 KFM13614.1 - 0 1115.3 67.1 0 1115.1 46.5 1.0 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D DUF869 PF05911.6 KFM13614.1 - 0.00016 20.1 67.8 0.0029 15.9 7.2 4.0 2 1 2 4 4 4 3 Plant protein of unknown function (DUF869) DUF1759 PF03564.10 KFM13614.1 - 0.0012 18.6 7.0 0.0012 18.6 4.9 5.4 4 1 0 5 5 5 1 Protein of unknown function (DUF1759) ApoO PF09769.4 KFM13614.1 - 0.025 14.3 6.9 0.86 9.2 0.1 3.7 2 1 0 2 2 2 0 Apolipoprotein O RhoGEF PF00621.15 KFM13615.1 - 2.3e-47 161.1 0.4 2.3e-47 161.1 0.3 1.7 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.24 KFM13615.1 - 7.5e-23 80.7 0.7 9e-13 48.3 0.0 2.9 2 0 0 2 2 2 2 PH domain FYVE PF01363.16 KFM13615.1 - 1.3e-18 66.6 11.0 3.1e-18 65.4 7.6 1.7 1 0 0 1 1 1 1 FYVE zinc finger PH_11 PF15413.1 KFM13615.1 - 1.8e-06 28.1 0.4 0.069 13.3 0.1 3.2 2 1 0 2 2 2 2 Pleckstrin homology domain PH_6 PF15406.1 KFM13615.1 - 0.001 19.0 0.0 2 8.5 0.0 2.7 2 0 0 2 2 2 2 Pleckstrin homology domain FYVE_2 PF02318.11 KFM13615.1 - 0.0021 17.9 13.3 0.0098 15.7 8.7 2.5 1 1 1 2 2 2 1 FYVE-type zinc finger PH_5 PF15405.1 KFM13615.1 - 0.024 14.6 0.3 3.6 7.5 0.0 3.1 1 1 1 2 2 2 0 Pleckstrin homology domain Presenilin PF01080.12 KFM13615.1 - 0.091 11.5 2.0 0.18 10.6 1.4 1.4 1 0 0 1 1 1 0 Presenilin zf-RING_5 PF14634.1 KFM13615.1 - 0.11 12.1 12.9 0.27 10.9 8.9 1.7 1 0 0 1 1 1 0 zinc-RING finger domain IBR PF01485.16 KFM13615.1 - 0.4 10.5 13.5 0.17 11.7 6.9 2.2 1 1 0 1 1 1 0 IBR domain zf-C3HC4_2 PF13923.1 KFM13615.1 - 5.2 7.1 10.8 18 5.4 7.4 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Dynamin_M PF01031.15 KFM13616.1 - 1.1e-100 336.2 0.1 2.8e-100 334.9 0.0 1.7 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 KFM13616.1 - 2.2e-50 170.7 0.6 9.4e-50 168.7 0.1 2.1 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 KFM13616.1 - 1.3e-32 111.5 2.8 4.6e-32 109.7 1.9 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain DUF3544 PF12064.3 KFM13616.1 - 0.099 12.4 0.1 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3544) Arm PF00514.18 KFM13617.1 - 4.7e-31 105.5 0.2 5.6e-09 35.5 0.0 7.1 7 0 0 7 7 7 4 Armadillo/beta-catenin-like repeat Arm_2 PF04826.8 KFM13617.1 - 4.1e-08 32.6 1.2 0.001 18.2 0.0 3.1 2 1 1 3 3 3 2 Armadillo-like HEAT_2 PF13646.1 KFM13617.1 - 5.6e-06 26.5 0.1 0.0075 16.5 0.0 2.9 2 1 0 2 2 2 2 HEAT repeats HEAT PF02985.17 KFM13617.1 - 0.0009 19.1 0.0 5 7.4 0.0 4.0 4 0 0 4 4 4 2 HEAT repeat Neurochondrin PF05536.6 KFM13617.1 - 0.03 12.6 1.0 0.71 8.1 0.2 2.6 2 1 1 3 3 3 0 Neurochondrin HEAT_EZ PF13513.1 KFM13617.1 - 0.062 13.8 0.7 12 6.5 0.0 3.9 4 0 0 4 4 4 0 HEAT-like repeat DUF383 PF04063.9 KFM13617.1 - 0.092 12.2 0.5 1.8 8.0 0.0 2.9 3 1 1 4 4 4 0 Domain of unknown function (DUF383) Atx10homo_assoc PF09759.4 KFM13617.1 - 0.095 12.4 0.0 3.1 7.5 0.0 3.1 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain Yae1_N PF09811.4 KFM13618.1 - 4.8e-11 42.0 34.7 0.00073 19.0 12.7 4.1 2 2 0 2 2 2 2 Essential protein Yae1, N terminal C2 PF00168.25 KFM13619.1 - 3.1e-56 187.1 0.3 1.1e-28 98.8 0.0 2.4 2 0 0 2 2 2 2 C2 domain PI3K_C2 PF00792.19 KFM13619.1 - 0.00062 19.5 0.0 2.2 8.0 0.0 3.4 3 1 0 3 3 3 2 Phosphoinositide 3-kinase C2 CEP76-C2 PF15627.1 KFM13619.1 - 0.0032 16.9 0.0 0.24 10.8 0.0 2.5 2 0 0 2 2 2 1 CEP76 C2 domain ETS_PEA3_N PF04621.8 KFM13619.1 - 0.011 14.9 2.0 0.018 14.3 1.4 1.2 1 0 0 1 1 1 0 PEA3 subfamily ETS-domain transcription factor N terminal domain Na_sulph_symp PF00939.14 KFM13621.1 - 4.8e-99 332.3 22.2 6e-99 332.0 15.4 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 KFM13621.1 - 9.4e-15 54.0 27.2 7.4e-07 28.0 7.2 3.1 2 1 1 3 3 3 3 Citrate transporter ArsB PF02040.10 KFM13621.1 - 6.2e-05 22.1 14.9 0.0068 15.4 2.6 2.7 3 0 0 3 3 3 2 Arsenical pump membrane protein SbmA_BacA PF05992.7 KFM13621.1 - 4.4 6.4 8.3 4.5 6.3 1.2 2.5 2 0 0 2 2 2 0 SbmA/BacA-like family FAM180 PF15173.1 KFM13622.1 - 2.4e-61 205.4 0.3 2.7e-61 205.3 0.2 1.0 1 0 0 1 1 1 1 FAM180 family Fox-1_C PF12414.3 KFM13622.1 - 0.051 13.9 0.0 0.078 13.3 0.0 1.3 1 0 0 1 1 1 0 Calcitonin gene-related peptide regulator C terminal Flag1_repress PF03614.8 KFM13622.1 - 0.076 12.5 0.1 0.11 12.0 0.1 1.3 1 1 0 1 1 1 0 Repressor of phase-1 flagellin Ank_2 PF12796.2 KFM13623.1 - 2.7e-24 85.3 0.0 3.9e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFM13623.1 - 6.2e-22 76.2 0.0 2e-09 36.7 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KFM13623.1 - 1.3e-20 73.3 0.1 9e-12 45.1 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM13623.1 - 1.4e-19 69.6 0.1 1.7e-10 40.8 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM13623.1 - 3.7e-16 57.6 0.1 2e-07 30.5 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat 7tm_1 PF00001.16 KFM13624.1 - 4.4e-81 271.7 7.2 6.6e-81 271.2 5.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) RAG2 PF03089.9 KFM13624.1 - 0.019 13.7 0.7 0.028 13.1 0.5 1.2 1 0 0 1 1 1 0 Recombination activating protein 2 PTN_MK_C PF01091.13 KFM13625.1 - 8.7e-30 102.5 10.3 8.7e-30 102.5 7.1 2.8 2 1 1 3 3 3 1 PTN/MK heparin-binding protein family, C-terminal domain PTN_MK_N PF05196.8 KFM13625.1 - 6.1e-28 96.5 17.3 6.1e-28 96.5 12.0 2.8 2 1 1 3 3 3 1 PTN/MK heparin-binding protein family, N-terminal domain ATP-synt_8 PF00895.15 KFM13625.1 - 0.34 11.1 0.0 0.34 11.1 0.0 2.8 3 0 0 3 3 3 0 ATP synthase protein 8 DAGK_acc PF00609.14 KFM13626.1 - 3.1e-47 160.6 0.0 6.6e-47 159.6 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 KFM13626.1 - 4.9e-32 110.0 0.0 9.9e-32 109.1 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Ank_2 PF12796.2 KFM13626.1 - 1.4e-30 105.4 6.6 4.3e-14 52.6 0.0 2.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) C1_1 PF00130.17 KFM13626.1 - 6.1e-15 54.6 27.3 7.7e-11 41.5 10.4 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Ank_5 PF13857.1 KFM13626.1 - 3.6e-12 46.0 0.2 7e-07 29.2 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KFM13626.1 - 7.2e-12 44.4 1.2 2.2e-05 24.0 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KFM13626.1 - 3e-11 43.4 0.0 5.5e-07 29.9 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM13626.1 - 9.9e-10 37.7 0.3 0.0015 18.6 0.1 3.2 2 0 0 2 2 2 2 Ankyrin repeat PHD_2 PF13831.1 KFM13626.1 - 3.2 7.1 9.7 8.9 5.7 1.7 2.8 2 0 0 2 2 2 0 PHD-finger bZIP_1 PF00170.16 KFM13627.1 - 1.6e-14 53.5 16.2 5.9e-14 51.7 11.0 2.0 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 KFM13627.1 - 3.2e-10 39.6 10.5 3.2e-10 39.6 7.2 2.2 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 KFM13627.1 - 1.2e-06 28.6 10.7 2.5e-06 27.7 7.4 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF904 PF06005.7 KFM13627.1 - 0.0045 17.2 2.8 0.014 15.6 2.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF904) FlaC_arch PF05377.6 KFM13627.1 - 0.0089 15.9 1.2 0.021 14.6 0.9 1.6 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) Fib_alpha PF08702.5 KFM13627.1 - 0.027 14.6 8.0 0.05 13.7 5.5 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family APG6 PF04111.7 KFM13627.1 - 0.074 12.0 7.4 0.12 11.3 5.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 TBCA PF02970.11 KFM13627.1 - 0.14 12.2 8.9 0.31 11.1 6.2 1.5 1 0 0 1 1 1 0 Tubulin binding cofactor A ADIP PF11559.3 KFM13627.1 - 0.19 11.6 10.8 0.33 10.8 7.5 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Herpes_BLRF2 PF05812.7 KFM13627.1 - 0.38 10.5 9.9 0.91 9.3 2.8 2.5 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein DUF1664 PF07889.7 KFM13627.1 - 0.59 9.9 4.4 0.97 9.2 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4404 PF14357.1 KFM13627.1 - 0.69 10.3 4.3 2.5 8.5 1.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) V_ATPase_I PF01496.14 KFM13627.1 - 1.4 6.6 5.1 2.1 6.0 3.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family COG2 PF06148.6 KFM13627.1 - 9 6.1 8.9 9.4 6.1 2.0 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 SSB PF00436.20 KFM13628.1 - 6.6e-31 106.2 0.2 7.8e-31 106.0 0.2 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Pkinase PF00069.20 KFM13629.1 - 4.3e-48 163.7 0.0 9.9e-48 162.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM13629.1 - 1.9e-23 82.8 0.0 4.2e-23 81.7 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase DUF2347 PF09804.4 KFM13630.1 - 2.3e-73 246.9 0.0 3e-73 246.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.5 KFM13630.1 - 9.7e-13 47.8 0.0 1.7e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 KFM13630.1 - 4.8e-10 38.4 0.1 0.0021 16.5 0.0 3.2 3 0 0 3 3 3 3 Transport protein Avl9 Ph1570 PF09638.5 KFM13630.1 - 0.075 12.8 0.1 0.51 10.1 0.1 2.3 2 0 0 2 2 2 0 Ph1570 protein DAGK_cat PF00781.19 KFM13631.1 - 2.2e-21 75.6 0.1 3.4e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.16 KFM13631.1 - 0.0011 17.8 0.0 0.0015 17.3 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase GATase PF00117.23 KFM13631.1 - 0.0049 16.3 0.0 0.008 15.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Tim54 PF11711.3 KFM13631.1 - 0.011 14.3 0.0 0.03 12.9 0.0 1.6 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 PaaX_C PF08223.6 KFM13631.1 - 0.026 14.2 0.7 0.044 13.4 0.5 1.3 1 0 0 1 1 1 0 PaaX-like protein C-terminal domain Claudin_2 PF13903.1 KFM13632.1 - 5.9e-13 48.8 5.6 7e-13 48.6 3.9 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 KFM13632.1 - 0.00014 21.6 4.5 0.0002 21.0 3.2 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Apq12 PF12716.2 KFM13632.1 - 0.08 12.6 0.7 0.2 11.3 0.5 1.7 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis MRP-S33 PF08293.6 KFM13633.1 - 6.8e-30 102.8 3.1 8.5e-30 102.5 2.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Herpes_UL36 PF03586.8 KFM13633.1 - 0.058 12.4 0.1 0.073 12.1 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein Pkinase_Tyr PF07714.12 KFM13634.1 - 1.9e-64 217.2 0.0 2.8e-64 216.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM13634.1 - 1e-60 205.1 0.0 1.5e-60 204.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RBD PF02196.10 KFM13634.1 - 2e-30 104.3 0.0 3.7e-30 103.4 0.0 1.5 1 0 0 1 1 1 1 Raf-like Ras-binding domain C1_1 PF00130.17 KFM13634.1 - 7.5e-12 44.7 6.7 1.4e-11 43.8 4.6 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.1 KFM13634.1 - 2.1e-09 36.7 0.0 3.1e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like zf-RING-like PF08746.6 KFM13634.1 - 0.00059 19.7 2.6 0.0014 18.5 1.8 1.6 1 0 0 1 1 1 1 RING-like domain C1_3 PF07649.7 KFM13634.1 - 0.072 13.1 5.3 0.15 12.1 3.7 1.6 1 0 0 1 1 1 0 C1-like domain Kdo PF06293.9 KFM13634.1 - 0.082 11.9 0.1 0.14 11.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFM13634.1 - 0.083 12.6 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Prok-RING_1 PF14446.1 KFM13634.1 - 0.23 11.2 1.8 0.55 10.0 1.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-AN1 PF01428.11 KFM13634.1 - 0.82 9.6 9.2 1.7 8.6 6.3 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger ABC1 PF03109.11 KFM13635.1 - 2.5e-20 72.6 0.0 1.1e-15 57.5 0.0 2.8 2 0 0 2 2 2 2 ABC1 family APH PF01636.18 KFM13635.1 - 0.0062 16.2 0.2 0.033 13.9 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KFM13635.1 - 0.081 12.2 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.20 KFM13635.1 - 0.12 11.4 0.2 1.2 8.2 0.0 2.4 3 0 0 3 3 3 0 Protein kinase domain DENN PF02141.16 KFM13637.1 - 6.8e-57 192.1 1.2 1.3e-56 191.2 0.8 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 KFM13637.1 - 1e-22 79.8 0.3 2e-22 78.9 0.2 1.5 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.14 KFM13637.1 - 2.4e-22 78.7 2.8 5.3e-22 77.6 1.9 1.6 1 0 0 1 1 1 1 dDENN domain SPA PF08616.5 KFM13637.1 - 0.22 11.2 0.2 0.49 10.1 0.1 1.5 1 0 0 1 1 1 0 Stabilization of polarity axis Indigoidine_A PF04227.7 KFM13638.1 - 2.4e-130 434.0 1.4 8.9e-130 432.1 0.7 1.8 2 0 0 2 2 2 1 Indigoidine synthase A like protein PfkB PF00294.19 KFM13638.1 - 3.6e-19 69.0 0.0 7.3e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 pfkB family carbohydrate kinase TPP_enzyme_N PF02776.13 KFM13638.1 - 0.031 13.7 0.4 0.31 10.4 0.0 2.8 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain zf-CCCH PF00642.19 KFM13639.1 - 2.4e-14 52.5 35.0 1.1e-05 25.0 0.1 4.4 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_2 PF13639.1 KFM13639.1 - 1.4e-07 31.2 5.1 7.1e-07 28.9 3.6 2.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KFM13639.1 - 5.4e-07 29.1 7.1 5.4e-07 29.1 4.9 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM13639.1 - 1.5e-05 24.6 6.0 1.5e-05 24.6 4.2 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 KFM13639.1 - 4e-05 23.6 6.0 4e-05 23.6 4.1 3.0 3 0 0 3 3 3 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KFM13639.1 - 0.00013 21.9 5.9 0.00013 21.9 4.1 3.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFM13639.1 - 0.00088 19.0 3.6 0.00088 19.0 2.5 3.1 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KFM13639.1 - 0.0023 17.6 2.8 0.0053 16.4 2.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KFM13639.1 - 0.0023 17.7 4.0 0.0023 17.7 2.8 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-CCCH_2 PF14608.1 KFM13639.1 - 0.0067 16.3 30.6 0.32 11.0 0.1 5.4 4 1 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type Ras PF00071.17 KFM13640.1 - 1.6e-56 190.1 0.6 1.8e-56 189.9 0.4 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM13640.1 - 1.8e-19 70.3 0.1 3.1e-19 69.6 0.1 1.4 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 KFM13640.1 - 2.1e-15 56.4 0.2 2.7e-15 56.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFM13640.1 - 2.7e-06 26.9 0.5 1e-05 25.0 0.4 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFM13640.1 - 1.5e-05 24.2 0.1 1.9e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFM13640.1 - 2.4e-05 24.2 0.1 3.4e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KFM13640.1 - 0.00023 20.4 0.1 0.00059 19.0 0.0 1.7 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 KFM13640.1 - 0.00046 19.4 0.6 0.061 12.6 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B PduV-EutP PF10662.4 KFM13640.1 - 0.0041 16.6 0.5 0.095 12.1 0.1 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 KFM13640.1 - 0.0096 16.0 0.1 0.017 15.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain ECIST_Cterm PF14784.1 KFM13640.1 - 0.039 13.9 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 C-terminal domain of the ECSIT protein Septin PF00735.13 KFM13640.1 - 0.069 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Septin G-alpha PF00503.15 KFM13640.1 - 0.12 11.0 0.8 12 4.4 0.0 2.8 1 1 1 2 2 2 0 G-protein alpha subunit MFS_1 PF07690.11 KFM13641.1 - 9.2e-40 136.4 29.2 2.2e-36 125.3 11.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily JmjC PF02373.17 KFM13642.1 - 1.3e-10 41.4 5.1 3e-10 40.3 1.4 2.8 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 KFM13642.1 - 7.9e-09 35.3 0.1 7.9e-09 35.3 0.1 2.7 2 0 0 2 2 2 1 Cupin-like domain AA_permease_2 PF13520.1 KFM13643.1 - 9.7e-52 175.9 36.8 1.1e-51 175.6 25.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFM13643.1 - 2.6e-26 92.0 26.9 2.6e-26 92.0 18.6 1.9 2 0 0 2 2 2 1 Amino acid permease PARP PF00644.15 KFM13644.1 - 8.5e-41 139.6 1.2 1.2e-39 135.8 0.8 1.9 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP PF00644.15 KFM13645.1 - 6.8e-34 117.0 0.3 6.3e-33 113.9 0.2 1.9 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Gmad2 PF10648.4 KFM13645.1 - 0.082 13.0 0.0 0.19 11.9 0.0 1.6 2 0 0 2 2 2 0 Immunoglobulin-like domain of bacterial spore germination Aldo_ket_red PF00248.16 KFM13646.1 - 9.2e-50 169.0 0.0 1.1e-49 168.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Bromodomain PF00439.20 KFM13647.1 - 1.2e-21 76.3 1.8 1.3e-21 76.2 0.1 2.0 2 0 0 2 2 2 1 Bromodomain zf-B_box PF00643.19 KFM13647.1 - 1.7e-11 43.7 22.6 5.4e-09 35.7 5.5 4.9 5 0 0 5 5 5 2 B-box zinc finger PHD PF00628.24 KFM13647.1 - 1.3e-08 34.3 10.3 1.3e-08 34.3 7.1 4.5 4 0 0 4 4 4 1 PHD-finger MFS_1 PF07690.11 KFM13648.1 - 2.9e-25 88.7 50.0 2.5e-19 69.2 17.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFM13648.1 - 4.1e-18 65.2 40.0 2.8e-15 55.8 9.0 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter V_ATPase_I PF01496.14 KFM13649.1 - 6.3e-296 983.2 6.3 7.2e-296 983.0 4.4 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family TMEM213 PF15192.1 KFM13650.1 - 1.3e-36 124.4 3.0 1.4e-36 124.3 2.1 1.0 1 0 0 1 1 1 1 TMEM213 family Pkinase PF00069.20 KFM13651.1 - 9e-54 182.3 0.0 1.7e-53 181.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM13651.1 - 3.5e-24 85.2 0.0 6e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFM13651.1 - 3.6e-06 26.2 0.0 7.8e-05 21.8 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFM13651.1 - 0.0046 16.7 0.0 0.0095 15.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KFM13651.1 - 0.0062 15.3 0.1 0.0093 14.7 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.4 KFM13651.1 - 0.1 11.9 0.0 0.25 10.6 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Tmemb_cc2 PF10267.4 KFM13651.1 - 1.9 6.9 6.7 4.5 5.7 4.7 1.6 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein p450 PF00067.17 KFM13652.1 - 4.9e-92 308.8 0.7 4.4e-72 243.0 0.1 2.0 2 0 0 2 2 2 2 Cytochrome P450 PARP PF00644.15 KFM13653.1 - 3.7e-42 144.0 2.5 2.9e-41 141.1 1.7 1.9 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Ets PF00178.17 KFM13654.1 - 1.7e-24 85.7 0.8 2.7e-24 85.0 0.5 1.3 1 0 0 1 1 1 1 Ets-domain I-set PF07679.11 KFM13655.1 - 7e-97 317.4 2.7 1.2e-19 69.9 0.0 7.6 8 0 0 8 8 7 7 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM13655.1 - 3.2e-46 155.3 0.0 4.9e-10 39.3 0.0 7.6 6 2 1 7 7 7 7 Immunoglobulin domain fn3 PF00041.16 KFM13655.1 - 1.4e-45 153.3 0.5 1e-13 51.2 0.0 5.3 5 0 0 5 5 5 3 Fibronectin type III domain ig PF00047.20 KFM13655.1 - 1.4e-26 92.3 0.1 4.8e-06 26.6 0.0 8.6 8 0 0 8 8 8 5 Immunoglobulin domain V-set PF07686.12 KFM13655.1 - 6.4e-25 87.2 1.1 8.8e-05 22.3 0.0 7.9 6 1 1 7 7 7 4 Immunoglobulin V-set domain Ig_3 PF13927.1 KFM13655.1 - 3e-21 75.6 0.6 2.6e-08 34.2 0.1 6.6 7 1 0 7 7 7 3 Immunoglobulin domain C2-set_2 PF08205.7 KFM13655.1 - 2.3e-10 40.2 0.4 0.11 12.3 0.0 6.4 7 0 0 7 7 7 3 CD80-like C2-set immunoglobulin domain C1-set PF07654.10 KFM13655.1 - 4.2e-07 29.8 3.3 4.8 7.2 0.0 6.1 6 0 0 6 6 6 1 Immunoglobulin C1-set domain Herpes_gI PF01688.12 KFM13655.1 - 0.016 14.3 0.0 7.7 5.6 0.0 4.3 6 0 0 6 6 6 0 Alphaherpesvirus glycoprotein I DUF3016 PF11454.3 KFM13655.1 - 0.029 13.9 0.1 0.25 10.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3016) DUF4251 PF14059.1 KFM13655.1 - 0.038 13.7 0.8 4.8 6.9 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4251) V-set_CD47 PF08204.6 KFM13655.1 - 0.073 12.8 0.8 12 5.7 0.0 3.4 3 0 0 3 3 3 0 CD47 immunoglobulin-like domain CDP-OH_P_transf PF01066.16 KFM13656.1 - 8e-14 51.7 11.4 1e-12 48.2 7.9 2.7 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Cor1 PF04803.7 KFM13657.1 - 1.9e-58 195.8 28.0 1.9e-58 195.8 19.4 1.6 2 0 0 2 2 2 1 Cor1/Xlr/Xmr conserved region UPF0020 PF01170.13 KFM13657.1 - 1.7 8.1 7.6 3.6 7.1 0.6 2.5 1 1 1 2 2 2 0 Putative RNA methylase family UPF0020 Vac_Fusion PF02346.11 KFM13657.1 - 2.8 7.4 8.5 0.64 9.4 1.9 2.9 2 1 1 3 3 3 0 Chordopoxvirus fusion protein Notch PF00066.12 KFM13658.1 - 6.4e-20 71.1 32.5 2.7e-11 43.5 9.4 2.4 2 0 0 2 2 2 2 LNR domain DMAP_binding PF06464.6 KFM13658.1 - 2.6e-11 44.1 0.2 7.7e-11 42.5 0.2 1.9 1 0 0 1 1 1 1 DMAP1-binding Domain DUF3184 PF11380.3 KFM13658.1 - 2.1e-07 29.3 4.3 0.0011 17.0 0.2 2.9 2 1 1 3 3 3 2 Protein of unknown function (DUF3184) EF-hand_1 PF00036.27 KFM13658.1 - 0.014 14.6 0.0 0.041 13.1 0.0 1.9 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.1 KFM13658.1 - 0.083 12.5 0.0 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair Frag1 PF10277.4 KFM13659.1 - 4.8e-39 134.0 15.2 5.6e-39 133.8 10.6 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family MFS_1 PF07690.11 KFM13659.1 - 0.04 12.6 10.2 0.015 13.9 1.7 2.1 1 1 1 2 2 2 0 Major Facilitator Superfamily GcpE PF04551.9 KFM13659.1 - 0.083 11.6 0.2 0.26 10.0 0.0 1.6 1 1 1 2 2 2 0 GcpE protein DUF2360 PF10152.4 KFM13660.1 - 1.5e-46 158.3 0.3 1.8e-46 158.0 0.2 1.1 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) WD40 PF00400.27 KFM13661.1 - 1.2e-16 59.9 2.2 2.6e-09 36.5 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 KFM13661.1 - 0.084 10.9 0.0 0.12 10.4 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 UvrD_C PF13361.1 KFM13663.1 - 5.9e-06 25.9 0.0 1.3e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Pro-MCH PF05824.7 KFM13664.1 - 4.5e-33 112.5 0.0 6.5e-33 112.0 0.0 1.2 1 0 0 1 1 1 1 Pro-melanin-concentrating hormone (Pro-MCH) Insulin PF00049.13 KFM13665.1 - 4.1e-15 56.3 5.9 2.1e-12 47.6 4.1 2.2 1 1 0 1 1 1 1 Insulin/IGF/Relaxin family Ins_beta PF03488.9 KFM13665.1 - 0.1 12.4 2.0 4.3 7.2 0.1 2.3 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type Biopterin_H PF00351.16 KFM13666.1 - 1.6e-172 572.7 0.7 2e-172 572.4 0.5 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase Biopterin_H PF00351.16 KFM13667.1 - 7.9e-189 626.3 0.1 1.3e-188 625.6 0.1 1.3 2 0 0 2 2 2 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.20 KFM13667.1 - 4.9e-09 35.4 0.0 1.1e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.1 KFM13667.1 - 0.0001 22.5 0.1 0.0011 19.2 0.0 2.2 2 0 0 2 2 2 1 ACT domain ACT_5 PF13710.1 KFM13667.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 ACT domain DUF1830 PF08865.6 KFM13668.1 - 0.01 15.4 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1830) Fasciclin PF02469.17 KFM13669.1 - 3.1e-128 421.6 0.6 1e-22 80.4 0.1 7.3 7 0 0 7 7 7 7 Fasciclin domain EGF_3 PF12947.2 KFM13669.1 - 2.4e-69 228.9 401.2 6.5e-10 38.8 8.7 25.7 25 1 0 25 25 25 16 EGF domain Xlink PF00193.12 KFM13669.1 - 1.1e-22 79.9 0.8 1.1e-22 79.9 0.5 5.4 7 0 0 7 7 7 1 Extracellular link domain EGF PF00008.22 KFM13669.1 - 0.00037 20.3 7.2 0.00037 20.3 5.0 26.4 26 0 0 26 26 26 15 EGF-like domain Laminin_EGF PF00053.19 KFM13669.1 - 0.0016 18.2 11.9 0.0016 18.2 8.3 30.6 13 6 19 32 32 32 4 Laminin EGF-like (Domains III and V) FXa_inhibition PF14670.1 KFM13669.1 - 0.003 17.6 9.8 0.003 17.6 6.8 27.3 19 5 5 24 24 24 8 Coagulation Factor Xa inhibitory site 5_nucleotid PF05761.9 KFM13670.1 - 1.8e-164 547.5 7.0 2.1e-164 547.3 4.8 1.0 1 0 0 1 1 1 1 5' nucleotidase family HAD_2 PF13419.1 KFM13670.1 - 0.00031 20.9 1.5 0.09 12.9 0.4 4.1 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Mu-transpos_C PF09299.6 KFM13670.1 - 0.13 12.1 1.0 0.78 9.6 0.1 2.7 2 0 0 2 2 2 0 Mu transposase, C-terminal HSP90 PF00183.13 KFM13671.1 - 2.9e-235 781.6 33.5 2.9e-235 781.6 23.2 1.7 2 0 0 2 2 2 1 Hsp90 protein HATPase_c_3 PF13589.1 KFM13671.1 - 1.8e-12 47.0 0.6 1.8e-12 47.0 0.4 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KFM13671.1 - 6.4e-12 45.1 0.3 1.3e-11 44.2 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MH1 PF03165.11 KFM13671.1 - 0.21 11.6 1.9 0.72 9.8 0.0 2.8 3 0 0 3 3 3 0 MH1 domain DUF4516 PF14990.1 KFM13672.1 - 1.9e-14 52.8 2.6 3.9e-14 51.9 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4516) UDG PF03167.14 KFM13673.1 - 1.1e-16 60.6 0.0 1.7e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily GAGA_bind PF06217.7 KFM13673.1 - 0.024 14.5 3.7 0.042 13.8 2.6 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Glyco_transf_8 PF01501.15 KFM13674.1 - 4.3e-46 157.2 0.0 5.3e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Kelch_3 PF13415.1 KFM13675.1 - 1.3e-34 117.5 8.0 3.2e-10 39.8 0.0 6.9 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 KFM13675.1 - 2.7e-31 106.9 4.8 1.1e-07 31.6 0.0 5.7 5 0 0 5 5 5 5 Kelch motif Kelch_4 PF13418.1 KFM13675.1 - 8.4e-27 92.7 3.0 9.3e-07 28.5 0.0 5.6 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_1 PF01344.20 KFM13675.1 - 1.5e-20 72.4 5.7 0.00022 20.6 0.1 5.8 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 KFM13675.1 - 2.9e-17 62.0 8.7 0.013 15.6 0.0 5.8 4 2 1 5 5 5 5 Kelch motif Kelch_2 PF07646.10 KFM13675.1 - 1.2e-15 56.5 6.2 0.034 13.9 0.1 5.9 5 0 0 5 5 5 5 Kelch motif fn3 PF00041.16 KFM13675.1 - 6e-11 42.3 0.7 0.023 14.8 0.0 4.3 4 0 0 4 4 4 3 Fibronectin type III domain CBFD_NFYB_HMF PF00808.18 KFM13676.1 - 5.8e-29 99.9 0.5 8.6e-29 99.4 0.4 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KFM13676.1 - 1.3e-06 28.4 0.0 2.5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 KFM13676.1 - 0.0011 18.6 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 KFM13676.1 - 0.068 12.9 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.8 KFM13676.1 - 0.1 12.9 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Pyr_redox_2 PF07992.9 KFM13677.1 - 7.7e-31 107.5 0.0 9.9e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KFM13677.1 - 3.6e-27 94.5 0.0 6.7e-27 93.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 KFM13677.1 - 2.2e-15 56.8 0.1 6.6e-15 55.2 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFM13677.1 - 3.6e-07 30.4 0.0 1e-06 28.9 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Sulfotransfer_2 PF03567.9 KFM13679.1 - 1.1e-68 231.6 8.1 1.4e-68 231.3 5.6 1.1 1 0 0 1 1 1 1 Sulfotransferase family DUF2115 PF09888.4 KFM13679.1 - 0.037 14.1 1.1 0.082 13.0 0.2 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) MgtE PF01769.11 KFM13680.1 - 2.4e-42 144.4 14.8 3.5e-27 95.3 2.9 3.1 4 0 0 4 4 4 2 Divalent cation transporter DUF4598 PF15370.1 KFM13681.1 - 3.1e-12 46.7 1.7 4.3e-12 46.3 1.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4598) Sigma70_r1_1 PF03979.9 KFM13681.1 - 0.0015 18.4 5.8 0.0025 17.6 4.0 1.4 1 0 0 1 1 1 1 Sigma-70 factor, region 1.1 Bd3614_N PF14442.1 KFM13681.1 - 0.0057 16.6 0.6 0.007 16.3 0.4 1.1 1 0 0 1 1 1 1 Bd3614-like deaminase N-terminal CENP-B_dimeris PF09026.5 KFM13681.1 - 2.4 8.4 6.4 8.7 6.6 3.0 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Aldedh PF00171.17 KFM13682.1 - 2.6e-173 576.6 0.0 3.2e-173 576.3 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Formyl_trans_N PF00551.14 KFM13682.1 - 9.1e-46 155.6 0.0 1.8e-45 154.7 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 KFM13682.1 - 2.5e-14 53.1 0.0 5.7e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain PP-binding PF00550.20 KFM13682.1 - 7.8e-06 26.0 0.0 1.6e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF1487 PF07368.6 KFM13682.1 - 0.0047 16.1 0.0 0.014 14.6 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) PID PF00640.18 KFM13683.1 - 2.1e-08 34.2 0.3 6.1e-08 32.7 0.2 1.8 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PH PF00169.24 KFM13683.1 - 7.7e-08 32.4 0.0 5.1e-07 29.8 0.0 2.4 2 0 0 2 2 2 1 PH domain PTB PF08416.8 KFM13683.1 - 1.6e-05 24.7 0.1 3.9e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PH_9 PF15410.1 KFM13683.1 - 0.0044 17.1 0.0 0.018 15.1 0.0 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain DUF3263 PF11662.3 KFM13683.1 - 0.0062 15.9 0.3 0.03 13.7 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3263) VPS9 PF02204.13 KFM13684.1 - 1.3e-23 82.9 0.8 2.7e-23 81.9 0.1 1.9 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain RA PF00788.18 KFM13684.1 - 2.8e-13 50.1 0.2 7.5e-13 48.7 0.1 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH2 PF00017.19 KFM13684.1 - 0.0019 17.9 0.0 0.0078 15.9 0.0 2.1 2 0 0 2 2 2 1 SH2 domain RelB PF04221.7 KFM13684.1 - 0.095 12.4 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 RelB antitoxin Na_Ca_ex PF01699.19 KFM13685.1 - 7.5e-55 184.3 34.2 1.4e-30 105.7 7.5 2.6 2 1 0 2 2 2 2 Sodium/calcium exchanger protein Herpes_LMP1 PF05297.6 KFM13685.1 - 0.011 14.7 0.5 0.011 14.7 0.3 3.2 3 0 0 3 3 3 0 Herpesvirus latent membrane protein 1 (LMP1) TFIIA PF03153.8 KFM13685.1 - 0.024 14.5 3.3 0.03 14.2 2.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PBP1_TM PF14812.1 KFM13685.1 - 0.08 13.2 2.2 0.084 13.1 0.5 1.8 2 0 0 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AF1Q PF15017.1 KFM13685.1 - 0.38 10.6 9.5 0.83 9.5 6.6 1.5 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator RXT2_N PF08595.6 KFM13685.1 - 0.88 9.3 4.8 0.72 9.6 2.1 1.7 2 0 0 2 2 2 0 RXT2-like, N-terminal Nucleoplasmin PF03066.10 KFM13685.1 - 1.3 8.5 11.1 1.2 8.6 6.3 1.8 2 0 0 2 2 2 0 Nucleoplasmin NOA36 PF06524.7 KFM13685.1 - 1.4 8.0 7.0 2.2 7.4 4.9 1.2 1 0 0 1 1 1 0 NOA36 protein Ribosomal_60s PF00428.14 KFM13685.1 - 1.5 9.2 5.8 3 8.2 4.0 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein SPC25 PF06703.6 KFM13685.1 - 2.1 7.8 6.0 2.4 7.7 0.3 2.7 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Nop14 PF04147.7 KFM13685.1 - 2.5 5.9 9.4 3.4 5.4 6.5 1.1 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.11 KFM13685.1 - 2.6 6.9 5.4 4.7 6.1 3.7 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF843 PF05814.6 KFM13685.1 - 2.9 7.7 7.6 0.44 10.3 0.6 2.5 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) HAT PF02184.11 KFM13686.1 - 9.1e-37 124.4 70.7 5.9e-16 57.9 0.8 14.4 13 2 0 13 13 13 7 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 KFM13686.1 - 7.7e-15 54.0 11.8 1.3 9.8 0.0 11.0 5 3 6 11 11 11 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFM13686.1 - 4.4e-14 52.7 9.1 0.0066 17.0 0.0 7.8 5 1 3 8 8 8 3 Tetratricopeptide repeat Suf PF05843.9 KFM13686.1 - 2.8e-09 37.0 38.3 0.00024 20.9 3.5 5.5 2 1 2 4 4 4 3 Suppressor of forked protein (Suf) TPR_19 PF14559.1 KFM13686.1 - 1.4e-05 25.3 11.3 0.026 14.8 0.0 7.2 7 1 4 11 11 10 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFM13686.1 - 3.3e-05 23.7 7.2 0.012 15.7 0.0 5.4 6 0 0 6 6 5 1 Tetratricopeptide repeat NRDE-2 PF08424.5 KFM13686.1 - 0.001 18.0 44.6 0.013 14.3 2.4 6.1 2 2 3 5 5 5 3 NRDE-2, necessary for RNA interference U3_assoc_6 PF08640.6 KFM13686.1 - 0.0021 17.7 1.3 0.0021 17.7 0.9 7.7 7 3 2 10 10 10 1 U3 small nucleolar RNA-associated protein 6 TPR_8 PF13181.1 KFM13686.1 - 0.0072 16.0 6.7 2.4 8.1 0.1 5.1 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFM13686.1 - 0.052 13.4 20.8 1.6 8.8 0.2 8.0 11 0 0 11 11 10 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFM13686.1 - 2.1 8.3 17.4 4.2 7.4 0.1 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat Pyr_redox_2 PF07992.9 KFM13687.1 - 0.00051 19.9 0.0 0.0016 18.3 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Acetyltransf_10 PF13673.1 KFM13687.1 - 0.011 15.8 0.1 0.26 11.3 0.0 2.9 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Pyr_redox_3 PF13738.1 KFM13687.1 - 0.013 15.6 0.0 4 7.4 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFM13687.1 - 0.12 12.8 0.0 6.3 7.2 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Rap_GAP PF02145.10 KFM13688.1 - 3.6e-65 218.8 0.0 6.5e-65 218.0 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP XRN_N PF03159.13 KFM13689.1 - 9.1e-105 349.2 0.2 1.8e-104 348.2 0.0 1.5 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus 7tm_1 PF00001.16 KFM13690.1 - 4.7e-68 229.1 13.3 5.4e-68 228.9 9.2 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM13690.1 - 4.3e-16 58.8 3.6 5.1e-16 58.6 2.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFM13690.1 - 2.2e-08 33.5 1.1 2.2e-08 33.5 0.8 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.4 KFM13690.1 - 0.00061 19.0 6.2 0.0065 15.6 0.0 2.4 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.4 KFM13690.1 - 0.00063 18.9 4.0 0.0012 18.0 2.2 1.8 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv Alg6_Alg8 PF03155.10 KFM13690.1 - 0.016 14.0 1.0 0.016 14.0 0.7 2.0 2 0 0 2 2 2 0 ALG6, ALG8 glycosyltransferase family Herpes_US9 PF06072.6 KFM13690.1 - 0.044 13.6 0.6 0.044 13.6 0.4 2.7 4 0 0 4 4 4 0 Alphaherpesvirus tegument protein US9 zf-H2C2_2 PF13465.1 KFM13691.1 - 9.1e-67 218.2 84.4 1.3e-09 37.8 0.5 12.0 12 0 0 12 12 12 11 Zinc-finger double domain zf-C2H2 PF00096.21 KFM13691.1 - 6e-45 148.9 99.6 3.8e-06 26.9 0.5 12.8 12 1 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM13691.1 - 6.7e-33 110.5 88.5 0.00011 22.3 0.6 12.1 12 0 0 12 12 12 12 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM13691.1 - 2.2e-18 65.8 59.9 0.029 14.5 0.0 11.7 12 0 0 12 12 12 10 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFM13691.1 - 5.2e-16 57.9 78.1 0.0012 18.7 0.6 13.9 12 2 0 12 12 12 8 C2H2-type zinc finger zf-met PF12874.2 KFM13691.1 - 2.2e-14 53.0 71.6 0.028 14.6 0.6 11.8 12 1 0 12 12 12 9 Zinc-finger of C2H2 type C1_1 PF00130.17 KFM13691.1 - 2.6e-05 23.8 57.1 0.018 14.7 0.1 9.1 1 1 6 7 7 7 3 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-CHY PF05495.7 KFM13691.1 - 0.0002 21.4 63.1 0.78 9.9 5.0 6.1 1 1 6 7 7 7 4 CHY zinc finger BolA PF01722.13 KFM13691.1 - 0.00025 20.9 8.1 2.3 8.2 0.1 5.2 3 2 1 4 4 4 2 BolA-like protein zf-C2HC_2 PF13913.1 KFM13691.1 - 0.00027 20.5 35.3 1.5 8.5 0.1 8.6 9 0 0 9 9 8 5 zinc-finger of a C2HC-type zf-FPG_IleRS PF06827.9 KFM13691.1 - 0.0011 18.5 22.3 9.2 6.0 0.0 8.8 9 0 0 9 9 9 0 Zinc finger found in FPG and IleRS Zn-ribbon_8 PF09723.5 KFM13691.1 - 0.0014 18.5 65.2 1.2 9.1 0.2 11.9 10 1 1 11 11 11 4 Zinc ribbon domain Ta0938 PF11494.3 KFM13691.1 - 0.099 12.7 15.5 0.72 9.9 0.6 4.1 2 1 2 4 4 3 0 Ta0938 PRP21_like_P PF12230.3 KFM13691.1 - 0.89 9.0 5.8 0.52 9.7 0.1 3.1 2 1 2 4 4 4 0 Pre-mRNA splicing factor PRP21 like protein IBD PF10416.4 KFM13691.1 - 1.3 8.8 6.8 45 3.8 0.0 4.2 2 2 1 3 3 3 0 Transcription-initiator DNA-binding domain IBD Baculo_IE-1 PF05290.6 KFM13691.1 - 3.5 7.3 34.5 0.8 9.4 1.6 6.7 3 3 3 6 6 6 0 Baculovirus immediate-early protein (IE-0) C1_2 PF03107.11 KFM13691.1 - 4.3 7.5 63.5 2.5 8.3 1.9 10.9 12 0 0 12 12 12 0 C1 domain SNAP PF14938.1 KFM13692.1 - 1.8e-102 342.3 22.3 2e-102 342.1 15.4 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 KFM13692.1 - 8.9e-08 31.9 13.6 0.0055 16.6 0.3 3.7 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFM13692.1 - 8.6e-06 25.1 11.3 0.025 14.3 0.0 6.1 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFM13692.1 - 0.00027 20.5 22.9 0.0093 15.5 2.3 4.5 2 1 3 5 5 5 4 TPR repeat TPR_10 PF13374.1 KFM13692.1 - 0.0012 18.7 4.8 1.7 8.6 0.1 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFM13692.1 - 0.0012 19.1 13.1 2.9 8.5 0.3 5.9 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFM13692.1 - 0.0028 18.1 4.8 10 7.0 0.0 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFM13692.1 - 0.0037 16.9 18.2 0.22 11.4 0.4 5.6 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFM13692.1 - 0.0063 16.3 20.7 1.4 9.0 0.0 5.9 7 0 0 7 7 6 3 Tetratricopeptide repeat MIT PF04212.13 KFM13692.1 - 0.019 14.8 14.3 9.7 6.1 0.3 5.3 4 1 1 5 5 5 0 MIT (microtubule interacting and transport) domain NSF PF02071.15 KFM13692.1 - 0.063 13.8 39.0 0.48 11.1 1.8 8.7 8 1 1 9 9 8 0 Aromatic-di-Alanine (AdAR) repeat Helicase_IV_N PF12462.3 KFM13692.1 - 0.084 12.5 1.8 0.47 10.0 0.2 2.3 2 0 0 2 2 2 0 DNA helicase IV / RNA helicase N terminal TPR_16 PF13432.1 KFM13692.1 - 0.097 13.3 7.2 4.7 8.0 1.6 3.6 2 1 2 4 4 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFM13692.1 - 0.13 12.6 7.3 0.65 10.3 1.7 3.5 2 2 1 3 3 3 0 Tetratricopeptide repeat Spatacsin_C PF14649.1 KFM13692.1 - 0.82 8.4 12.1 0.31 9.8 0.7 2.8 1 1 0 2 2 2 0 Spatacsin C-terminus CBP PF12192.3 KFM13692.1 - 1.7 8.6 5.5 8.5 6.4 0.4 4.2 5 1 0 5 5 4 0 Fungal calcium binding protein Foie-gras_1 PF11817.3 KFM13692.1 - 2 7.8 9.7 1.9 7.9 1.4 3.0 2 1 1 3 3 3 0 Foie gras liver health family 1 Sel1 PF08238.7 KFM13692.1 - 7.2 7.3 14.9 3.5 8.3 0.4 4.8 5 1 0 5 5 4 0 Sel1 repeat zf-CCCH PF00642.19 KFM13693.1 - 2.8e-09 36.4 19.0 4.4e-05 23.0 0.9 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KFM13693.1 - 0.0055 16.6 17.1 0.17 11.9 1.1 3.6 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type Pkinase_Tyr PF07714.12 KFM13694.1 - 9.6e-91 303.4 0.0 1.3e-90 303.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM13694.1 - 3.6e-43 147.6 0.0 5e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ig_2 PF13895.1 KFM13694.1 - 1e-15 57.5 0.1 8e-08 32.2 0.1 2.6 2 0 0 2 2 2 2 Immunoglobulin domain fn3 PF00041.16 KFM13694.1 - 8.1e-15 54.7 0.6 5.2e-07 29.6 0.3 2.6 2 0 0 2 2 2 2 Fibronectin type III domain I-set PF07679.11 KFM13694.1 - 1.4e-11 44.0 0.0 7.9e-05 22.4 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_3 PF13927.1 KFM13694.1 - 2.4e-11 43.9 4.6 5e-07 30.1 0.4 3.5 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.20 KFM13694.1 - 2.9e-06 27.2 0.6 0.17 12.0 0.0 3.6 3 2 0 3 3 3 2 Immunoglobulin domain V-set PF07686.12 KFM13694.1 - 0.00014 21.7 0.4 0.061 13.2 0.0 3.1 3 0 0 3 3 3 1 Immunoglobulin V-set domain Kinase-like PF14531.1 KFM13694.1 - 0.016 14.1 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Apc1 PF12859.2 KFM13695.1 - 8.4e-19 67.7 0.1 8.4e-19 67.7 0.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 KFM13695.1 - 4.7e-06 26.5 17.8 0.0019 18.3 0.0 5.7 6 0 0 6 6 6 3 Proteasome/cyclosome repeat Mad3_BUB1_I PF08311.7 KFM13696.1 - 9.9e-36 122.2 0.0 8.2e-35 119.3 0.0 2.3 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 KFM13696.1 - 6.3e-16 58.2 0.0 1.1e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM13696.1 - 3e-07 29.7 0.0 4.7e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase AAA_23 PF13476.1 KFM13696.1 - 0.6 10.4 6.1 1.3 9.3 4.2 1.4 1 0 0 1 1 1 0 AAA domain Ion_trans PF00520.26 KFM13697.1 - 1.5e-08 34.1 9.1 2e-08 33.7 6.3 1.2 1 0 0 1 1 1 1 Ion transport protein Med17 PF10156.4 KFM13697.1 - 0.0074 14.6 0.1 0.0081 14.4 0.1 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex DUF3139 PF11337.3 KFM13697.1 - 0.035 14.3 1.1 0.035 14.3 0.7 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3139) UPF0182 PF03699.8 KFM13697.1 - 0.091 10.6 0.1 0.089 10.7 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) DUF1240 PF06836.7 KFM13697.1 - 2.1 8.6 6.8 0.65 10.2 2.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) Ion_trans PF00520.26 KFM13698.1 - 8.4e-16 57.8 22.4 1.5e-15 57.0 15.5 1.4 1 0 0 1 1 1 1 Ion transport protein Tmemb_185A PF10269.4 KFM13698.1 - 1.4 8.4 20.0 0.02 14.5 5.2 2.5 1 1 0 2 2 2 0 Transmembrane Fragile-X-F protein GP41 PF00517.12 KFM13698.1 - 2.3 7.7 4.4 0.96 8.9 0.2 2.0 2 0 0 2 2 2 0 Retroviral envelope protein MARVEL PF01284.18 KFM13699.1 - 1.6e-10 40.9 11.0 1.8e-10 40.7 7.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain Ank_2 PF12796.2 KFM13700.1 - 4e-85 280.2 7.2 8.3e-24 83.7 0.0 4.7 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KFM13700.1 - 1.6e-61 201.1 2.6 5.3e-08 32.2 0.0 9.3 9 0 0 9 9 9 9 Ankyrin repeat Ank_4 PF13637.1 KFM13700.1 - 3.5e-50 167.5 0.3 5.1e-12 45.9 0.0 6.5 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM13700.1 - 1.7e-42 142.4 3.2 1.2e-06 28.5 0.1 8.6 1 1 6 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM13700.1 - 9.6e-40 130.6 0.9 1.4e-05 24.8 0.0 9.6 9 0 0 9 9 9 7 Ankyrin repeat SOCS_box PF07525.11 KFM13700.1 - 1.3e-13 50.5 5.8 2.5e-13 49.6 4.0 1.5 1 0 0 1 1 1 1 SOCS box DUF1394 PF07159.7 KFM13700.1 - 0.025 13.6 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1394) ChaC PF04752.7 KFM13701.1 - 4.3e-38 131.0 0.0 4.9e-38 130.8 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein LRR_8 PF13855.1 KFM13702.1 - 8.5e-38 127.9 41.2 3.9e-10 39.3 0.1 9.2 6 2 2 8 8 8 7 Leucine rich repeat LRR_4 PF12799.2 KFM13702.1 - 1.5e-33 113.8 51.9 1e-05 25.0 0.1 11.7 9 3 2 11 11 11 9 Leucine Rich repeats (2 copies) TIR PF01582.15 KFM13702.1 - 8.9e-31 106.2 0.4 1.6e-30 105.3 0.3 1.4 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.28 KFM13702.1 - 1.1e-23 79.5 40.7 0.019 14.9 0.0 17.4 16 2 2 18 18 18 8 Leucine Rich Repeat TIR_2 PF13676.1 KFM13702.1 - 1.1e-11 44.7 0.0 2.4e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_6 PF13516.1 KFM13702.1 - 3.4e-09 35.8 40.1 0.13 12.4 0.0 13.8 14 1 1 15 15 15 3 Leucine Rich repeat LRR_7 PF13504.1 KFM13702.1 - 1.1e-06 27.8 34.1 9.1 6.9 0.0 13.5 18 0 0 18 18 18 1 Leucine rich repeat Phage_C PF12025.3 KFM13702.1 - 0.046 13.6 1.0 0.12 12.3 0.1 2.1 2 0 0 2 2 2 0 Phage protein C LRR_9 PF14580.1 KFM13702.1 - 0.12 11.9 6.1 5.7 6.4 0.1 4.2 3 1 0 4 4 4 0 Leucine-rich repeat Acylphosphatase PF00708.13 KFM13703.1 - 4.5e-16 58.7 0.0 5.2e-16 58.5 0.0 1.0 1 0 0 1 1 1 1 Acylphosphatase PH_7 PF15408.1 KFM13703.1 - 0.13 12.0 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain WD40 PF00400.27 KFM13704.1 - 2.4e-82 268.1 79.6 3.1e-05 23.6 0.2 30.2 33 0 0 33 33 33 20 WD domain, G-beta repeat HELP PF03451.9 KFM13704.1 - 1.4e-47 159.1 3.2 3.5e-17 61.6 0.0 3.6 3 0 0 3 3 3 3 HELP motif Nucleoporin_N PF08801.6 KFM13704.1 - 4.5e-06 25.6 0.0 0.051 12.3 0.0 4.4 4 0 0 4 4 4 1 Nup133 N terminal like Cytochrom_D1 PF02239.11 KFM13704.1 - 9.4e-05 20.8 10.3 0.81 7.9 0.0 6.2 6 1 1 7 7 7 2 Cytochrome D1 heme domain Apc4_WD40 PF12894.2 KFM13704.1 - 0.00033 20.0 0.0 0.8 9.2 0.0 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3312 PF11768.3 KFM13704.1 - 0.00048 18.4 0.0 0.096 10.8 0.0 3.6 4 0 0 4 4 4 1 Protein of unknown function (DUF3312) PD40 PF07676.7 KFM13704.1 - 0.00051 19.6 0.1 38 4.1 0.0 5.7 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat ATP-grasp PF02222.17 KFM13704.1 - 0.068 12.5 0.0 11 5.3 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain TruB_C PF09142.6 KFM13704.1 - 0.071 12.7 0.0 19 5.0 0.0 3.7 4 0 0 4 4 4 0 tRNA Pseudouridine synthase II, C terminal Reticulon PF02453.12 KFM13705.1 - 1.5e-30 106.0 2.0 2.7e-30 105.2 1.4 1.4 1 0 0 1 1 1 1 Reticulon ubiquitin PF00240.18 KFM13706.1 - 6.7e-30 102.2 0.4 1.2e-29 101.4 0.2 1.5 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.14 KFM13706.1 - 1.2e-28 98.6 4.0 2.2e-28 97.7 2.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 KFM13706.1 - 7.2e-15 54.4 0.1 1.5e-14 53.3 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KFM13706.1 - 5.2e-06 26.6 0.2 3.1e-05 24.1 0.0 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 KFM13706.1 - 0.00041 20.1 0.4 0.00075 19.3 0.3 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KFM13706.1 - 0.014 15.5 0.5 0.02 15.0 0.4 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 KFM13706.1 - 0.051 13.6 0.4 0.1 12.6 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 KFM13706.1 - 0.12 10.6 0.8 0.18 10.0 0.2 1.5 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain GTP_EFTU PF00009.22 KFM13707.1 - 6.2e-39 133.3 2.1 5.2e-38 130.3 1.4 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KFM13707.1 - 4.7e-29 100.4 1.1 4.7e-29 100.4 0.8 2.5 3 0 0 3 3 3 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 KFM13707.1 - 1.3e-10 41.2 0.1 4e-07 30.0 0.0 3.1 2 0 0 2 2 2 2 Elongation factor Tu domain 2 Miro PF08477.8 KFM13707.1 - 5e-08 33.4 0.3 3e-07 30.9 0.0 2.5 2 1 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 KFM13707.1 - 5e-07 29.6 0.7 1.2e-06 28.4 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Arf PF00025.16 KFM13707.1 - 3.8e-05 22.9 0.4 0.00021 20.5 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU_D4 PF14578.1 KFM13707.1 - 0.00032 20.2 2.0 0.68 9.6 0.1 2.8 2 0 0 2 2 2 2 Elongation factor Tu domain 4 Ras PF00071.17 KFM13707.1 - 0.00054 19.3 0.0 0.002 17.5 0.0 2.0 2 0 0 2 2 2 1 Ras family FeoB_N PF02421.13 KFM13707.1 - 0.0017 17.6 0.1 0.008 15.4 0.1 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 KFM13707.1 - 0.0018 17.4 1.1 0.011 14.9 0.1 2.6 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 KFM13707.1 - 0.023 14.5 3.0 0.83 9.4 0.0 3.1 2 1 1 3 3 3 0 Dynamin family IF2_N PF04760.10 KFM13707.1 - 0.026 14.1 2.1 0.37 10.4 0.1 2.6 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region PduV-EutP PF10662.4 KFM13707.1 - 0.044 13.2 0.6 0.42 10.1 0.1 2.6 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_26 PF13500.1 KFM13707.1 - 0.19 11.3 0.1 0.19 11.3 0.0 2.5 4 0 0 4 4 4 0 AAA domain tRNA_edit PF04073.10 KFM13708.1 - 3.2e-24 85.1 0.0 3.6e-24 84.9 0.0 1.0 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain HTH_10 PF04967.7 KFM13708.1 - 0.1 12.1 0.0 0.46 10.0 0.0 1.9 2 0 0 2 2 2 0 HTH DNA binding domain ARL2_Bind_BART PF11527.3 KFM13709.1 - 1.5e-24 86.1 5.3 1.5e-24 86.1 3.7 1.5 2 0 0 2 2 2 1 The ARF-like 2 binding protein BART Ppx-GppA PF02541.11 KFM13709.1 - 0.0063 15.7 1.5 0.0087 15.2 1.0 1.1 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Motilin_assoc PF04643.7 KFM13709.1 - 0.13 11.8 2.5 0.18 11.3 0.3 2.3 2 0 0 2 2 2 0 Motilin/ghrelin-associated peptide OSCP PF00213.13 KFM13709.1 - 0.24 11.2 2.8 0.51 10.1 2.0 1.8 1 1 0 1 1 1 0 ATP synthase delta (OSCP) subunit SMK-1 PF04802.10 KFM13710.1 - 1.7e-73 246.2 6.9 2.1e-72 242.7 2.7 2.9 3 0 0 3 3 3 2 Component of IIS longevity pathway SMK-1 IGF2_C PF08365.6 KFM13710.1 - 0.081 12.6 1.2 0.15 11.8 0.1 2.0 2 0 0 2 2 2 0 Insulin-like growth factor II E-peptide RNase_PH PF01138.16 KFM13711.1 - 6e-41 139.8 0.0 4.4e-20 72.3 0.0 2.4 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KFM13711.1 - 4.9e-18 64.8 0.7 2.8e-10 40.0 0.0 2.7 2 0 0 2 2 2 2 3' exoribonuclease family, domain 2 PNPase PF03726.9 KFM13711.1 - 2.4e-09 37.3 1.3 4.6e-09 36.4 0.1 2.2 2 0 0 2 2 2 1 Polyribonucleotide nucleotidyltransferase, RNA binding domain S1 PF00575.18 KFM13711.1 - 2.2e-07 30.8 0.0 2.2e-06 27.6 0.0 2.5 3 0 0 3 3 3 1 S1 RNA binding domain KH_1 PF00013.24 KFM13711.1 - 0.0001 21.8 0.0 0.0005 19.6 0.0 2.3 2 0 0 2 2 2 1 KH domain OAF PF14941.1 KFM13711.1 - 0.0059 15.7 0.1 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator, Out at first EGF_CA PF07645.10 KFM13712.1 - 2.4e-48 161.8 90.2 7.1e-14 51.5 5.3 8.0 8 0 0 8 8 8 6 Calcium-binding EGF domain cEGF PF12662.2 KFM13712.1 - 2.7e-35 119.6 58.7 1.5e-10 40.4 0.3 7.6 8 0 0 8 8 8 6 Complement Clr-like EGF-like FXa_inhibition PF14670.1 KFM13712.1 - 2.4e-10 40.3 36.7 3.2e-07 30.3 4.9 7.7 8 1 0 8 8 8 4 Coagulation Factor Xa inhibitory site EGF PF00008.22 KFM13712.1 - 8.8e-07 28.7 22.3 6.9e-05 22.7 5.7 8.3 9 1 0 9 9 9 5 EGF-like domain EGF_3 PF12947.2 KFM13712.1 - 1.3e-05 25.0 18.3 4.3e-05 23.3 6.4 8.2 7 2 1 8 8 8 4 EGF domain EGF_MSP1_1 PF12946.2 KFM13712.1 - 0.0012 18.5 40.6 0.11 12.3 0.7 6.8 5 1 1 6 6 6 3 MSP1 EGF domain 1 hEGF PF12661.2 KFM13712.1 - 0.0073 16.3 38.8 0.32 11.1 2.1 7.8 7 0 0 7 7 7 4 Human growth factor-like EGF DUF2216 PF10226.4 KFM13713.1 - 4.1e-100 333.1 13.7 9.4e-100 332.0 8.9 1.9 2 0 0 2 2 2 1 Uncharacterized conserved proteins (DUF2216) DUF605 PF04652.11 KFM13713.1 - 0.0059 16.0 10.3 0.0072 15.7 7.1 1.2 1 0 0 1 1 1 1 Vta1 like bZIP_1 PF00170.16 KFM13713.1 - 0.069 13.1 12.4 0.53 10.2 0.1 3.4 3 0 0 3 3 3 0 bZIP transcription factor TSC22 PF01166.13 KFM13713.1 - 0.15 12.0 11.3 7.9 6.5 0.1 4.0 3 0 0 3 3 3 0 TSC-22/dip/bun family DUF972 PF06156.8 KFM13713.1 - 3 8.2 9.3 26 5.2 0.2 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF972) NYD-SP28_assoc PF14775.1 KFM13713.1 - 8.7 6.1 9.8 15 5.3 0.3 3.3 3 0 0 3 3 3 0 Sperm tail C-terminal domain 7tm_1 PF00001.16 KFM13714.1 - 8e-47 159.5 11.8 1e-46 159.2 8.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFM13714.1 - 5.6e-11 42.0 10.1 7.1e-11 41.7 7.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF63 PF01889.12 KFM13714.1 - 0.00086 19.4 2.0 0.0017 18.4 1.4 1.5 1 1 0 1 1 1 1 Membrane protein of unknown function DUF63 ABC2_membrane_5 PF13346.1 KFM13714.1 - 0.011 15.0 0.4 0.011 15.0 0.3 2.4 2 1 0 2 2 2 0 ABC-2 family transporter protein CDI PF02234.14 KFM13715.1 - 3.9e-19 68.1 0.4 4.4e-19 68.0 0.3 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor Coat_F PF07875.7 KFM13715.1 - 0.082 13.0 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Coat F domain CDI PF02234.14 KFM13716.1 - 2.4e-22 78.4 3.0 3.8e-22 77.8 2.1 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor Ion_trans_2 PF07885.11 KFM13717.1 - 4.5e-13 48.7 5.8 5.4e-13 48.4 4.0 1.2 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.26 KFM13717.1 - 5e-11 42.2 1.5 5.5e-11 42.0 1.0 1.0 1 0 0 1 1 1 1 Ion transport protein DUF2798 PF11391.3 KFM13717.1 - 0.04 13.6 0.5 0.081 12.6 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2798) DUF996 PF06195.8 KFM13717.1 - 0.056 13.4 0.4 0.078 12.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF996) Nuc_sug_transp PF04142.10 KFM13717.1 - 0.082 11.9 0.2 0.11 11.5 0.1 1.1 1 0 0 1 1 1 0 Nucleotide-sugar transporter MRP-S28 PF10213.4 KFM13718.1 - 6.1e-32 110.3 0.3 1e-31 109.6 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Kelch_1 PF01344.20 KFM13720.1 - 5.1e-30 102.7 10.1 5.3e-10 38.6 0.0 6.0 6 1 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 KFM13720.1 - 1.7e-26 91.2 6.6 4.1e-08 33.0 0.0 6.0 5 2 1 6 6 6 5 Kelch motif Kelch_5 PF13854.1 KFM13720.1 - 2.3e-11 43.3 0.3 0.00011 22.0 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 KFM13720.1 - 9.6e-11 41.0 0.8 0.0075 15.9 0.0 4.9 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.1 KFM13720.1 - 5.9e-10 39.0 0.5 0.094 12.9 0.0 5.3 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.1 KFM13720.1 - 5.8e-09 35.5 4.4 0.047 13.4 0.0 5.2 5 1 0 5 5 5 2 Galactose oxidase, central domain BTB PF00651.26 KFM13720.1 - 2.9e-05 24.0 0.0 0.00055 19.8 0.0 2.4 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.10 KFM13720.1 - 0.0052 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Parathyroid PF01279.12 KFM13721.1 - 9.5e-38 128.8 0.6 9.5e-38 128.8 0.4 1.5 2 0 0 2 2 2 1 Parathyroid hormone family NEAT PF05031.7 KFM13721.1 - 0.097 12.6 0.8 0.14 12.1 0.6 1.1 1 0 0 1 1 1 0 Iron Transport-associated domain Herpes_DNAp_acc PF04929.7 KFM13721.1 - 0.37 9.7 4.2 0.43 9.4 2.9 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor zf-H2C2_2 PF13465.1 KFM13723.1 - 2.2e-21 74.9 17.9 1.8e-09 37.4 0.8 3.0 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KFM13723.1 - 1.7e-15 56.2 14.1 3.3e-08 33.4 0.1 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KFM13723.1 - 7.3e-11 41.8 6.7 0.00051 20.1 0.1 3.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KFM13723.1 - 1e-08 34.8 9.8 0.0023 18.1 0.2 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFM13723.1 - 4.5e-07 29.5 10.9 0.025 14.4 0.1 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger TFIIS_C PF01096.13 KFM13723.1 - 0.00032 20.2 9.3 0.62 9.7 0.2 3.3 3 0 0 3 3 3 2 Transcription factor S-II (TFIIS) C1_1 PF00130.17 KFM13723.1 - 0.0016 18.1 6.2 0.037 13.7 1.0 2.4 1 1 1 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 KFM13723.1 - 0.0021 17.7 5.9 1.5 8.6 0.0 3.1 3 0 0 3 3 3 1 Prokaryotic RING finger family 1 XPA_N PF01286.13 KFM13723.1 - 0.0022 17.6 10.5 0.31 10.7 0.0 3.1 3 0 0 3 3 3 1 XPA protein N-terminal DNA_RNApol_7kD PF03604.8 KFM13723.1 - 0.0034 16.8 5.8 2.1 7.9 0.1 3.2 3 0 0 3 3 3 1 DNA directed RNA polymerase, 7 kDa subunit Zn_Tnp_IS1595 PF12760.2 KFM13723.1 - 0.0052 16.5 12.0 0.17 11.6 3.9 2.9 2 1 0 2 2 2 1 Transposase zinc-ribbon domain zf-CHY PF05495.7 KFM13723.1 - 0.0059 16.7 5.2 0.0081 16.2 3.6 1.2 1 0 0 1 1 1 1 CHY zinc finger Zn-ribbon_8 PF09723.5 KFM13723.1 - 0.0063 16.4 15.4 0.59 10.1 4.6 3.1 1 1 0 2 2 2 1 Zinc ribbon domain zf-met PF12874.2 KFM13723.1 - 0.0078 16.3 12.7 0.32 11.2 0.3 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-BED PF02892.10 KFM13723.1 - 0.0095 15.6 12.4 0.14 11.8 0.9 3.1 1 1 2 3 3 3 2 BED zinc finger C1_4 PF07975.7 KFM13723.1 - 0.016 15.1 11.2 0.15 12.0 2.3 2.9 1 1 2 3 3 3 0 TFIIH C1-like domain zf-trcl PF13451.1 KFM13723.1 - 0.016 14.8 7.2 3.2 7.4 0.1 3.1 3 0 0 3 3 3 0 Probable zinc-binding domain zf-LYAR PF08790.6 KFM13723.1 - 0.019 14.6 4.6 0.78 9.5 0.0 3.3 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-AN1 PF01428.11 KFM13723.1 - 0.021 14.6 8.3 1.9 8.3 0.2 3.1 3 0 0 3 3 3 0 AN1-like Zinc finger LIM PF00412.17 KFM13723.1 - 0.023 14.7 6.7 0.33 11.0 4.5 2.2 1 1 1 2 2 2 0 LIM domain C1_3 PF07649.7 KFM13723.1 - 0.025 14.6 5.4 5 7.2 0.1 3.3 3 1 0 3 3 3 0 C1-like domain DZR PF12773.2 KFM13723.1 - 0.026 14.3 6.6 0.81 9.5 4.6 2.3 1 1 0 1 1 1 0 Double zinc ribbon SprT-like PF10263.4 KFM13723.1 - 0.045 13.4 5.5 0.71 9.5 3.8 2.0 1 1 0 1 1 1 0 SprT-like family zf-RING_3 PF14369.1 KFM13723.1 - 0.051 13.5 3.7 6.3 6.8 0.1 3.0 3 0 0 3 3 3 0 zinc-finger CpXC PF14353.1 KFM13723.1 - 0.095 12.6 6.2 0.36 10.7 0.6 2.9 2 1 0 2 2 2 0 CpXC protein Cytochrom_CIII PF02085.11 KFM13723.1 - 0.16 12.0 7.2 0.39 10.8 4.9 1.6 1 1 0 1 1 1 0 Class III cytochrome C family zf-UBP PF02148.14 KFM13723.1 - 0.22 11.6 5.9 0.76 9.9 0.1 2.6 1 1 1 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein DUF2387 PF09526.5 KFM13723.1 - 0.24 11.3 6.7 3.9 7.4 4.7 2.3 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) zf-UBR PF02207.15 KFM13723.1 - 0.31 10.7 9.2 7.2 6.4 0.2 3.0 1 1 2 3 3 3 0 Putative zinc finger in N-recognin (UBR box) zf-HIT PF04438.11 KFM13723.1 - 0.38 10.4 9.3 2.5 7.8 0.2 3.0 3 0 0 3 3 3 0 HIT zinc finger zf-Di19 PF05605.7 KFM13723.1 - 0.43 10.7 4.8 0.25 11.5 0.8 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Evr1_Alr PF04777.8 KFM13723.1 - 0.64 9.9 8.2 3.6 7.5 0.1 2.9 1 1 2 3 3 3 0 Erv1 / Alr family c-SKI_SMAD_bind PF08782.5 KFM13723.1 - 0.7 10.0 3.8 1.5 8.9 2.6 1.7 1 1 0 1 1 1 0 c-SKI Smad4 binding domain HypA PF01155.14 KFM13723.1 - 0.71 9.5 7.8 0.37 10.4 1.9 2.1 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Mut7-C PF01927.11 KFM13723.1 - 0.81 9.6 8.5 0.39 10.6 1.9 2.1 1 1 1 2 2 2 0 Mut7-C RNAse domain PHD PF00628.24 KFM13723.1 - 0.93 9.2 10.0 14 5.4 6.7 2.3 1 1 1 2 2 2 0 PHD-finger Elf1 PF05129.8 KFM13723.1 - 1.1 9.0 7.9 0.23 11.1 1.7 2.1 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zinc-ribbons_6 PF07191.7 KFM13723.1 - 1.3 8.8 6.7 22 4.9 0.2 3.0 1 1 0 2 2 2 0 zinc-ribbons COX5B PF01215.14 KFM13723.1 - 1.4 8.6 8.4 3.8 7.1 0.5 2.6 1 1 2 3 3 3 0 Cytochrome c oxidase subunit Vb zinc_ribbon_5 PF13719.1 KFM13723.1 - 1.4 8.5 8.6 20 4.8 0.1 3.0 2 1 1 3 3 3 0 zinc-ribbon domain zf-C2H2_2 PF12756.2 KFM13723.1 - 1.6 8.9 7.3 4.1 7.5 3.0 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Fer4_17 PF13534.1 KFM13723.1 - 1.7 9.0 8.3 8.2 6.8 0.1 3.0 2 1 1 3 3 3 0 4Fe-4S dicluster domain zinc_ribbon_4 PF13717.1 KFM13723.1 - 1.9 8.2 8.9 24 4.7 0.1 3.0 2 1 1 3 3 3 0 zinc-ribbon domain DUF2256 PF10013.4 KFM13723.1 - 2.1 8.1 7.0 8.4 6.2 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) YhfH PF14149.1 KFM13723.1 - 2.2 8.1 13.1 2 8.2 0.1 3.0 3 0 0 3 3 3 0 YhfH-like protein DUF3725 PF12523.3 KFM13723.1 - 2.3 8.3 7.4 5.4 7.1 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3725) DUF3268 PF11672.3 KFM13723.1 - 2.4 8.2 5.4 0.67 10.0 0.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3268) Desulfoferrod_N PF06397.7 KFM13723.1 - 2.5 7.5 8.7 3.4 7.1 0.2 3.1 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain Fer4_2 PF12797.2 KFM13723.1 - 2.5 8.1 5.7 18 5.5 0.1 3.0 3 0 0 3 3 3 0 4Fe-4S binding domain Rpr2 PF04032.11 KFM13723.1 - 2.8 7.8 5.5 1.1 9.1 0.9 2.0 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain A2L_zn_ribbon PF08792.5 KFM13723.1 - 2.9 7.4 12.3 11 5.6 0.3 3.2 3 0 0 3 3 3 0 A2L zinc ribbon domain zf-H2C2_5 PF13909.1 KFM13723.1 - 2.9 8.2 15.2 14 6.1 2.1 3.8 3 1 0 3 3 3 0 C2H2-type zinc-finger domain RNHCP PF12647.2 KFM13723.1 - 3 7.7 6.3 33 4.4 2.4 2.8 2 1 0 2 2 2 0 RNHCP domain C1_2 PF03107.11 KFM13723.1 - 3.6 7.7 7.4 16 5.7 0.3 3.0 3 0 0 3 3 3 0 C1 domain FYVE PF01363.16 KFM13723.1 - 3.8 7.4 9.9 42 4.1 6.8 2.4 1 1 0 1 1 1 0 FYVE zinc finger Fer4_4 PF12800.2 KFM13723.1 - 4 8.0 6.9 28 5.4 0.1 3.1 3 0 0 3 3 3 0 4Fe-4S binding domain DUF2072 PF09845.4 KFM13723.1 - 4.2 7.3 8.0 2.3 8.1 0.1 2.8 2 1 0 3 3 3 0 Zn-ribbon containing protein (DUF2072) Tnp_zf-ribbon_2 PF13842.1 KFM13723.1 - 4.2 7.8 12.1 1.2e+03 -0.0 8.2 2.9 1 1 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon Fer4_10 PF13237.1 KFM13723.1 - 4.4 7.1 6.7 16 5.3 0.0 3.0 2 1 0 2 2 2 0 4Fe-4S dicluster domain Ogr_Delta PF04606.7 KFM13723.1 - 4.4 7.0 8.1 1.3 8.7 1.8 2.5 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger OrfB_Zn_ribbon PF07282.6 KFM13723.1 - 4.4 7.0 9.8 8.7 6.0 2.4 2.9 1 1 2 3 3 3 0 Putative transposase DNA-binding domain HNH PF01844.18 KFM13723.1 - 5.1 7.0 7.0 7.2 6.5 0.1 2.7 3 0 0 3 3 3 0 HNH endonuclease Zn_ribbon_recom PF13408.1 KFM13723.1 - 5.1 7.4 8.4 4.6 7.5 1.0 2.2 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Ribosomal_L37ae PF01780.14 KFM13723.1 - 5.2 7.0 9.6 21 5.0 0.4 2.9 1 1 1 2 2 2 0 Ribosomal L37ae protein family zf-ISL3 PF14690.1 KFM13723.1 - 6.7 6.8 12.0 12 6.0 0.7 3.2 2 2 1 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 TF_Zn_Ribbon PF08271.7 KFM13723.1 - 7.8 5.9 10.4 24 4.3 0.4 3.2 3 0 0 3 3 3 0 TFIIB zinc-binding zinc_ribbon_2 PF13240.1 KFM13723.1 - 8.7 5.9 11.1 4.8 6.8 0.5 2.9 3 0 0 3 3 3 0 zinc-ribbon domain NinG PF05766.7 KFM13723.1 - 9.3 5.9 11.1 9.2 5.9 0.2 3.0 1 1 2 3 3 3 0 Bacteriophage Lambda NinG protein TPR_5 PF12688.2 KFM13724.1 - 0.33 10.9 3.3 9.8 6.2 0.4 2.6 1 1 2 3 3 3 0 Tetratrico peptide repeat zf-H2C2_2 PF13465.1 KFM13725.1 - 3.2e-69 226.0 62.5 2e-09 37.2 2.4 8.8 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.21 KFM13725.1 - 4.2e-57 187.1 69.8 4.9e-08 32.8 1.4 8.3 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KFM13725.1 - 7e-28 95.6 47.4 6e-07 29.1 0.1 8.2 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KFM13725.1 - 6.5e-27 91.8 62.0 6.2e-05 23.0 1.4 8.1 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM13725.1 - 7.2e-10 38.7 36.5 0.027 14.6 0.0 7.8 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding C1_1 PF00130.17 KFM13725.1 - 1.2e-08 34.5 24.7 0.055 13.1 0.4 5.6 1 1 7 8 8 8 8 Phorbol esters/diacylglycerol binding domain (C1 domain) XPA_N PF01286.13 KFM13725.1 - 6.3e-08 32.1 30.3 0.49 10.1 0.1 8.0 8 0 0 8 8 8 3 XPA protein N-terminal Zn-ribbon_8 PF09723.5 KFM13725.1 - 5.1e-07 29.5 44.7 0.82 9.6 0.1 7.8 5 3 1 6 6 6 5 Zinc ribbon domain DNA_RNApol_7kD PF03604.8 KFM13725.1 - 2.3e-05 23.7 34.3 2.8 7.4 0.4 8.1 8 0 0 8 8 8 3 DNA directed RNA polymerase, 7 kDa subunit LIM PF00412.17 KFM13725.1 - 3.1e-05 23.9 31.9 0.11 12.6 2.5 5.8 2 2 4 6 6 6 3 LIM domain Zn_Tnp_IS1595 PF12760.2 KFM13725.1 - 8.3e-05 22.3 48.8 0.16 11.8 3.5 6.2 3 3 3 6 6 6 3 Transposase zinc-ribbon domain Yippee-Mis18 PF03226.9 KFM13725.1 - 0.00062 19.7 23.2 0.74 9.8 0.1 6.2 4 1 1 5 5 5 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-LYAR PF08790.6 KFM13725.1 - 0.00099 18.7 36.9 0.69 9.6 0.1 8.0 8 0 0 8 8 8 3 LYAR-type C2HC zinc finger zf-met PF12874.2 KFM13725.1 - 0.0015 18.6 52.5 0.059 13.6 0.5 7.6 8 0 0 8 8 7 4 Zinc-finger of C2H2 type MBD PF01429.14 KFM13725.1 - 0.0018 17.7 2.3 3.9 7.0 0.5 3.7 1 1 1 2 2 2 2 Methyl-CpG binding domain DZR PF12773.2 KFM13725.1 - 0.0024 17.6 35.1 1.5e+04 -17.0 24.3 5.5 1 1 0 1 1 0 0 Double zinc ribbon FYDLN_acid PF09538.5 KFM13725.1 - 0.0035 17.9 21.3 6 7.4 0.1 6.9 1 1 4 5 5 5 0 Protein of unknown function (FYDLN_acid) zf-Di19 PF05605.7 KFM13725.1 - 0.0055 16.8 37.6 0.66 10.1 2.3 5.9 1 1 3 6 6 6 3 Drought induced 19 protein (Di19), zinc-binding C1_4 PF07975.7 KFM13725.1 - 0.018 15.0 34.5 0.33 11.0 0.5 6.5 1 1 7 8 8 8 0 TFIIH C1-like domain zf-UBP PF02148.14 KFM13725.1 - 0.018 15.1 35.5 0.68 10.0 0.1 6.0 2 2 3 5 5 5 0 Zn-finger in ubiquitin-hydrolases and other protein SASRP1 PF15160.1 KFM13725.1 - 0.024 13.8 0.1 17 4.5 0.0 3.8 1 1 3 5 5 5 0 Spermatogenesis-associated serine-rich protein 1 zf-trcl PF13451.1 KFM13725.1 - 0.17 11.5 34.7 3 7.5 0.1 7.8 7 1 0 7 7 7 0 Probable zinc-binding domain Zn_ribbon_recom PF13408.1 KFM13725.1 - 0.24 11.6 41.5 12 6.2 2.5 6.6 1 1 4 5 5 4 0 Recombinase zinc beta ribbon domain YhfH PF14149.1 KFM13725.1 - 0.24 11.1 31.6 15 5.4 0.1 7.8 8 0 0 8 8 8 0 YhfH-like protein C1_3 PF07649.7 KFM13725.1 - 0.48 10.5 27.5 9.2 6.4 0.1 7.9 8 0 0 8 8 8 0 C1-like domain zf-AN1 PF01428.11 KFM13725.1 - 1.4 8.8 45.2 2.2 8.2 0.2 8.1 5 2 3 8 8 8 0 AN1-like Zinc finger UPF0547 PF10571.4 KFM13725.1 - 1.5 8.5 38.8 1.2 8.8 0.2 7.4 8 0 0 8 8 8 0 Uncharacterised protein family UPF0547 zf-IS66 PF13005.2 KFM13725.1 - 2 8.4 28.9 15 5.6 0.2 7.9 7 1 2 9 9 9 0 zinc-finger binding domain of transposase IS66 TFIIS_C PF01096.13 KFM13725.1 - 2 8.1 40.7 5.7 6.6 0.2 8.0 7 1 0 7 7 7 0 Transcription factor S-II (TFIIS) Siva PF05458.7 KFM13725.1 - 2.5 7.6 14.4 1.3 8.6 0.8 2.9 1 1 1 3 3 3 0 Cd27 binding protein (Siva) HypA PF01155.14 KFM13725.1 - 2.9 7.5 30.9 7 6.3 1.1 4.9 1 1 4 5 5 5 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_2 PF13240.1 KFM13725.1 - 3.2 7.3 40.3 0.5 9.9 1.2 6.8 5 3 1 6 6 6 0 zinc-ribbon domain zf-RING_3 PF14369.1 KFM13725.1 - 5.4 7.1 33.6 3.7 7.6 0.1 7.6 7 1 1 8 8 8 0 zinc-finger DUF2072 PF09845.4 KFM13725.1 - 5.8 6.8 33.4 4.8 7.1 0.6 6.9 5 3 2 7 7 7 0 Zn-ribbon containing protein (DUF2072) RhoGEF PF00621.15 KFM13726.1 - 1.3e-37 129.3 3.2 1.3e-37 129.3 2.2 1.6 2 0 0 2 2 2 1 RhoGEF domain SH3_1 PF00018.23 KFM13726.1 - 3.6e-11 42.2 0.1 7.5e-11 41.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFM13726.1 - 8.6e-10 38.0 0.0 1.8e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFM13726.1 - 5e-09 35.5 0.0 8.7e-09 34.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 KFM13726.1 - 0.049 13.8 0.2 0.19 11.9 0.0 2.1 2 1 0 2 2 2 0 PH domain Homeobox PF00046.24 KFM13727.1 - 2.4e-23 81.4 2.2 3.6e-23 80.9 1.5 1.3 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFM13727.1 - 0.00016 21.3 0.0 0.00029 20.4 0.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain HTH_23 PF13384.1 KFM13727.1 - 0.032 13.8 0.1 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain DUF1323 PF07037.6 KFM13727.1 - 0.078 13.1 0.7 0.12 12.5 0.5 1.3 1 0 0 1 1 1 0 Putative transcription regulator (DUF1323) Tetraspannin PF00335.15 KFM13728.1 - 9.4e-42 142.7 13.4 1.1e-41 142.5 9.3 1.1 1 0 0 1 1 1 1 Tetraspanin family Shisa PF13908.1 KFM13728.1 - 0.0063 16.7 4.3 0.05 13.7 1.3 2.1 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator Claudin_2 PF13903.1 KFM13728.1 - 0.1 12.2 5.8 0.048 13.3 1.3 2.1 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction PrgI PF12666.2 KFM13728.1 - 0.53 10.4 5.5 0.37 10.9 0.8 2.3 2 0 0 2 2 2 0 PrgI family protein Oxidored_q3 PF00499.15 KFM13728.1 - 0.64 9.8 9.0 1.6 8.5 5.9 1.9 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Tic20 PF09685.5 KFM13728.1 - 0.71 9.8 8.3 1.5 8.8 2.9 2.1 2 0 0 2 2 2 0 Tic20-like protein Cytochrom_B561 PF03188.11 KFM13728.1 - 0.8 9.5 9.0 0.15 11.9 2.6 2.1 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 DUF2207 PF09972.4 KFM13728.1 - 1.7 7.0 3.8 0.49 8.9 0.3 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) IBV_3C PF03620.8 KFM13728.1 - 3 7.7 7.5 13 5.7 4.0 2.6 1 1 1 2 2 2 0 IBV 3C protein NfeD PF01957.13 KFM13728.1 - 9.1 6.4 11.5 3.5 7.7 0.5 2.9 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding VWD PF00094.20 KFM13729.1 - 2.6e-26 92.6 0.5 6.1e-26 91.4 0.4 1.5 1 1 0 1 1 1 1 von Willebrand factor type D domain RGM_N PF06535.7 KFM13729.1 - 0.053 13.5 0.3 0.091 12.7 0.2 1.5 1 0 0 1 1 1 0 Repulsive guidance molecule (RGM) N-terminus C8 PF08742.6 KFM13730.1 - 8.9e-19 67.5 6.2 8.9e-19 67.5 4.3 2.0 2 0 0 2 2 2 1 C8 domain TIL PF01826.12 KFM13730.1 - 3.8e-07 30.1 14.4 3.8e-07 30.1 10.0 2.7 2 1 0 2 2 2 1 Trypsin Inhibitor like cysteine rich domain Anoctamin PF04547.7 KFM13731.1 - 2.5e-142 474.7 13.9 3.1e-142 474.3 9.6 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel DUF2207 PF09972.4 KFM13731.1 - 0.0093 14.5 0.6 0.16 10.5 0.4 2.3 2 0 0 2 2 2 1 Predicted membrane protein (DUF2207) NGF PF00243.13 KFM13732.1 - 7.6e-61 202.9 4.9 1.2e-60 202.3 3.4 1.3 1 0 0 1 1 1 1 Nerve growth factor family DUF573 PF04504.9 KFM13732.1 - 0.096 12.9 0.9 0.2 11.9 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF573 Ion_trans PF00520.26 KFM13733.1 - 2e-37 128.4 2.1 6.4e-37 126.7 0.6 2.0 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 KFM13733.1 - 1.4e-23 82.8 0.1 2.5e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.11 KFM13733.1 - 7e-14 51.3 4.3 7e-14 51.3 3.0 2.2 2 0 0 2 2 2 1 Ion channel PKD_channel PF08016.7 KFM13733.1 - 0.00011 20.7 0.9 0.00022 19.7 0.6 1.4 1 0 0 1 1 1 1 Polycystin cation channel DUF202 PF02656.10 KFM13733.1 - 1.1 9.5 4.8 45 4.3 0.0 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF202) ELO PF01151.13 KFM13734.1 - 2.5e-65 220.2 23.8 2.8e-65 220.0 16.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Ion_trans PF00520.26 KFM13735.1 - 2.8e-35 121.3 5.8 2.8e-35 121.3 4.0 1.9 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 KFM13735.1 - 5.8e-29 100.1 0.6 1.1e-28 99.2 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans_2 PF07885.11 KFM13735.1 - 1.1e-13 50.7 5.3 1.1e-13 50.7 3.7 2.7 2 1 2 4 4 4 1 Ion channel PKD_channel PF08016.7 KFM13735.1 - 0.00075 18.0 1.0 0.0016 16.9 0.7 1.5 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 KFM13736.1 - 2.5e-35 121.5 4.2 4e-35 120.8 1.7 1.9 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 KFM13736.1 - 2.5e-27 94.8 0.0 4.3e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.11 KFM13736.1 - 2.8e-12 46.1 7.1 2.8e-12 46.1 4.9 2.8 3 0 0 3 3 3 1 Ion channel PKD_channel PF08016.7 KFM13736.1 - 0.00078 17.9 2.1 0.0013 17.2 1.5 1.4 1 0 0 1 1 1 1 Polycystin cation channel DUF423 PF04241.10 KFM13736.1 - 0.11 12.4 0.1 0.32 10.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF423) DUF202 PF02656.10 KFM13736.1 - 3.8 7.7 7.0 35 4.7 0.0 3.5 2 1 0 2 2 2 0 Domain of unknown function (DUF202) RVT_1 PF00078.22 KFM13737.1 - 1e-16 60.9 0.0 1.4e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Arg_repressor PF01316.16 KFM13737.1 - 0.052 13.1 0.1 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain Glycos_transf_2 PF00535.21 KFM13738.1 - 1.3e-19 70.4 0.0 2.1e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 KFM13738.1 - 4.3e-11 42.9 0.0 7.2e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.1 KFM13738.1 - 2.8e-05 24.0 0.0 0.00014 21.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 KFM13738.1 - 0.00041 19.7 0.0 0.00089 18.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase 3Beta_HSD PF01073.14 KFM13739.1 - 6.2e-13 48.0 0.0 3.6e-06 25.9 0.0 2.1 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KFM13739.1 - 3e-12 46.4 0.0 5.9e-11 42.2 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFM13739.1 - 3.2e-12 46.8 0.0 5e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KFM13739.1 - 7.4e-11 41.7 0.0 3.4e-10 39.5 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 KFM13739.1 - 7.1e-10 38.2 0.0 6.8e-06 25.1 0.0 2.3 2 1 0 2 2 2 2 RmlD substrate binding domain NAD_binding_4 PF07993.7 KFM13739.1 - 2.2e-05 23.5 0.0 0.1 11.4 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein Cyclin_N PF00134.18 KFM13741.1 - 1.2e-35 121.8 1.4 1.2e-35 121.8 1.0 1.5 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFM13741.1 - 4.6e-23 81.4 0.9 2e-22 79.3 0.0 2.3 3 1 0 3 3 3 1 Cyclin, C-terminal domain K-cyclin_vir_C PF09080.5 KFM13741.1 - 0.017 15.2 0.0 0.03 14.5 0.0 1.3 1 0 0 1 1 1 0 K cyclin, C terminal FGF PF00167.13 KFM13742.1 - 1.1e-22 80.0 0.1 1.6e-22 79.5 0.1 1.2 1 0 0 1 1 1 1 Fibroblast growth factor FGF PF00167.13 KFM13743.1 - 1.3e-41 141.1 0.0 1.7e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Fibroblast growth factor DUF2362 PF10154.4 KFM13744.1 - 3.7e-238 791.2 14.9 4.2e-238 791.1 10.3 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) Synaptonemal_3 PF15191.1 KFM13748.1 - 1e-34 118.1 7.1 1.1e-34 118.0 4.9 1.0 1 0 0 1 1 1 1 Synaptonemal complex central element protein 3 CENP-F_leu_zip PF10473.4 KFM13748.1 - 0.0022 17.8 3.3 0.0034 17.2 2.3 1.3 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Med9 PF07544.8 KFM13748.1 - 0.018 14.7 0.8 4.4 7.0 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 PHA_synth_III_E PF09712.5 KFM13748.1 - 0.049 13.0 0.4 0.057 12.8 0.3 1.0 1 0 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Lyase_8_N PF08124.6 KFM13748.1 - 0.083 11.7 0.8 0.086 11.7 0.5 1.0 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain HALZ PF02183.13 KFM13748.1 - 0.097 12.4 0.9 0.17 11.5 0.6 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper Pkinase_Tyr PF07714.12 KFM13749.1 - 2.8e-64 216.7 0.0 4.6e-64 216.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM13749.1 - 8e-32 110.3 0.0 1.6e-31 109.4 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.1 KFM13749.1 - 3.6e-05 22.8 0.0 6.4e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like TMEM154 PF15102.1 KFM13749.1 - 0.0033 17.1 0.1 0.0053 16.4 0.1 1.3 1 0 0 1 1 1 1 TMEM154 protein family 7tm_1 PF00001.16 KFM13749.1 - 0.066 12.3 0.1 0.1 11.7 0.1 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Shisa PF13908.1 KFM13749.1 - 0.084 13.0 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Atg8 PF02991.11 KFM13750.1 - 2.4e-49 165.6 0.2 2.7e-49 165.4 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 KFM13750.1 - 3.4e-08 33.5 0.0 4.2e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 VitD-bind_III PF09164.5 KFM13750.1 - 0.094 12.3 0.2 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 Vitamin D binding protein, domain III TMEM52 PF14979.1 KFM13751.1 - 3.4e-62 208.9 0.3 3.9e-62 208.7 0.2 1.0 1 0 0 1 1 1 1 Transmembrane 52 Corona_S2 PF01601.11 KFM13751.1 - 0.032 12.3 2.0 0.042 11.9 1.4 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein DUF3481 PF11980.3 KFM13751.1 - 0.4 10.5 3.7 0.73 9.7 2.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3481) WBP-1 PF11669.3 KFM13751.1 - 0.88 9.6 5.2 0.97 9.5 3.1 1.6 1 1 1 2 2 2 0 WW domain-binding protein 1 LSR PF05624.9 KFM13751.1 - 3.6 7.3 11.6 5.6 6.7 8.1 1.3 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) Lectin_C PF00059.16 KFM13752.1 - 8.8e-14 52.0 4.5 8.8e-14 52.0 3.1 2.1 3 0 0 3 3 3 1 Lectin C-type domain Ly49 PF08391.5 KFM13752.1 - 0.043 13.9 0.1 0.094 12.8 0.0 1.6 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region VirB8 PF04335.8 KFM13752.1 - 0.35 10.4 1.8 0.56 9.7 1.3 1.2 1 0 0 1 1 1 0 VirB8 protein Sulfotransfer_1 PF00685.22 KFM13753.1 - 2.5e-10 40.0 0.0 5.8e-09 35.5 0.0 3.2 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 KFM13753.1 - 0.00023 22.1 0.0 0.001 20.0 0.0 2.2 1 0 0 1 1 1 1 Sulfotransferase family Yae1_N PF09811.4 KFM13754.1 - 1.5e-18 66.0 57.0 1.5e+04 -17.8 39.5 5.2 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Peptidase_C1 PF00112.18 KFM13755.1 - 9.4e-53 179.3 8.8 9.4e-53 179.3 6.1 1.7 2 0 0 2 2 2 1 Papain family cysteine protease Pacifastin_I PF05375.8 KFM13755.1 - 0.00033 20.0 3.4 0.0015 18.0 2.3 2.2 1 0 0 1 1 1 1 Pacifastin inhibitor (LCMII) Propeptide_C1 PF08127.8 KFM13755.1 - 0.0015 18.1 0.0 0.0034 16.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase family C1 propeptide Somatomedin_B PF01033.12 KFM13755.1 - 0.018 15.0 16.1 0.018 15.0 11.2 2.6 2 0 0 2 2 2 0 Somatomedin B domain Peptidase_C1_2 PF03051.10 KFM13755.1 - 0.1 11.0 3.6 0.061 11.8 0.7 1.9 2 1 1 3 3 3 0 Peptidase C1-like family MLIP PF15274.1 KFM13756.1 - 2.7e-72 243.3 0.8 2.7e-72 243.3 0.6 1.7 2 0 0 2 2 2 1 Muscular LMNA-interacting protein LRR_4 PF12799.2 KFM13757.1 - 9.7e-47 155.9 51.8 2e-08 33.6 0.1 9.1 5 3 4 9 9 9 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFM13757.1 - 4.3e-35 119.2 38.7 7.4e-09 35.2 3.2 7.2 3 2 3 7 7 7 7 Leucine rich repeat LRR_1 PF00560.28 KFM13757.1 - 2.6e-25 84.5 46.6 0.1 12.7 0.0 14.5 15 0 0 15 15 15 11 Leucine Rich Repeat LRR_7 PF13504.1 KFM13757.1 - 1.8e-13 48.3 49.9 0.89 10.0 0.0 15.0 15 0 0 15 15 15 7 Leucine rich repeat LRR_9 PF14580.1 KFM13757.1 - 4.3e-07 29.6 14.1 0.0014 18.2 1.9 4.2 2 1 2 4 4 4 3 Leucine-rich repeat Tropomyosin_1 PF12718.2 KFM13757.1 - 0.087 12.6 2.3 0.24 11.2 1.6 1.6 1 0 0 1 1 1 0 Tropomyosin like BLOC1_2 PF10046.4 KFM13757.1 - 0.28 11.3 2.7 0.35 11.0 0.2 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Kelch_1 PF01344.20 KFM13758.1 - 2.5e-51 170.9 7.8 2.6e-11 42.8 0.0 6.8 6 1 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 KFM13758.1 - 1e-34 117.2 5.9 4.9e-09 35.9 0.1 6.2 2 1 4 6 6 6 5 Kelch motif BACK PF07707.10 KFM13758.1 - 1.2e-25 89.3 0.1 2.4e-25 88.3 0.1 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_3 PF13415.1 KFM13758.1 - 2.5e-25 87.9 1.6 1.5e-06 28.1 0.0 5.0 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_4 PF13418.1 KFM13758.1 - 5e-23 80.6 0.4 3.2e-05 23.5 0.0 5.6 5 0 0 5 5 5 5 Galactose oxidase, central domain BTB PF00651.26 KFM13758.1 - 7.3e-22 77.4 1.0 1.2e-21 76.7 0.3 1.7 2 0 0 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.10 KFM13758.1 - 5e-19 67.2 6.2 1.7e-07 30.6 0.2 6.7 6 1 0 6 6 6 3 Kelch motif Kelch_5 PF13854.1 KFM13758.1 - 3.7e-12 45.9 4.3 0.0034 17.3 0.1 5.6 5 0 0 5 5 5 4 Kelch motif DUF1668 PF07893.8 KFM13758.1 - 0.05 12.7 0.0 0.18 10.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1668) GCS PF03074.11 KFM13759.1 - 7.3e-198 657.0 0.4 9e-198 656.7 0.3 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.8 KFM13759.1 - 0.04 13.0 0.0 0.085 11.9 0.0 1.5 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) ELO PF01151.13 KFM13760.1 - 2.8e-68 229.9 25.3 3.5e-68 229.6 17.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family GCM PF03615.10 KFM13761.1 - 1.9e-74 248.0 4.6 3.5e-74 247.1 3.2 1.4 1 0 0 1 1 1 1 GCM motif protein F-box-like PF12937.2 KFM13762.1 - 1.3e-11 44.0 1.5 2.4e-11 43.1 1.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFM13762.1 - 2.9e-08 33.1 1.5 5.5e-08 32.2 1.0 1.5 1 0 0 1 1 1 1 F-box domain MIT PF04212.13 KFM13762.1 - 0.00039 20.2 0.8 0.00069 19.4 0.6 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_11 PF13414.1 KFM13762.1 - 0.035 13.7 0.2 0.068 12.8 0.2 1.4 1 0 0 1 1 1 0 TPR repeat Elongin_A PF06881.6 KFM13762.1 - 0.15 12.4 2.7 1.1 9.7 0.0 2.6 3 0 0 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Pkinase PF00069.20 KFM13763.1 - 1e-75 254.2 0.0 1.5e-75 253.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM13763.1 - 2.6e-37 128.3 0.1 1.1e-36 126.3 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFM13763.1 - 0.0071 15.3 0.0 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like tRNA-synt_1g PF09334.6 KFM13763.1 - 0.095 11.3 0.3 0.15 10.7 0.2 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (M) GST_N PF02798.15 KFM13764.1 - 2.5e-17 62.8 0.0 7e-17 61.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFM13764.1 - 1.1e-16 60.5 0.1 3.5e-16 58.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFM13764.1 - 0.001 18.8 0.1 0.003 17.4 0.0 1.8 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFM13764.1 - 0.058 13.8 0.0 0.11 13.0 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KFM13765.1 - 5.1e-18 65.0 0.0 1.6e-17 63.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFM13765.1 - 1.9e-16 59.8 0.0 3.3e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KFM13765.1 - 0.0044 17.1 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFM13765.1 - 0.0093 15.8 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFM13765.1 - 0.021 15.3 0.0 0.033 14.6 0.0 1.4 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KFM13766.1 - 1.4e-18 66.7 0.0 3.4e-18 65.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFM13766.1 - 9.7e-14 51.1 0.1 1.5e-13 50.5 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KFM13766.1 - 0.0049 17.0 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFM13766.1 - 0.051 13.4 0.0 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KFM13767.1 - 9.4e-17 60.9 0.0 2.1e-16 59.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFM13767.1 - 7.7e-15 54.6 0.0 1.5e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KFM13767.1 - 0.0034 17.5 0.0 0.0061 16.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFM13767.1 - 0.004 17.0 0.1 0.008 16.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFM13767.1 - 0.032 14.7 0.0 0.059 13.8 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Tmemb_14 PF03647.8 KFM13768.1 - 1.7e-28 98.8 7.7 1.9e-28 98.6 5.3 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C PMT_2 PF13231.1 KFM13768.1 - 0.066 13.0 5.0 0.078 12.8 3.5 1.1 1 0 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF2232 PF09991.4 KFM13768.1 - 0.092 11.7 6.3 0.1 11.6 4.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Gly-zipper_OmpA PF13436.1 KFM13768.1 - 0.13 11.9 1.4 0.16 11.6 0.9 1.1 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain DUF2613 PF11021.3 KFM13768.1 - 0.15 11.7 1.3 0.16 11.6 0.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2613) Glug PF07581.7 KFM13768.1 - 0.54 10.5 4.9 1.9 8.8 0.1 2.5 3 0 0 3 3 3 0 The GLUG motif DUF4131 PF13567.1 KFM13768.1 - 2.7 7.3 7.5 4.3 6.7 0.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Acyltransferase PF01553.16 KFM13769.1 - 3.1e-19 68.7 0.0 6.5e-19 67.6 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase BRCT PF00533.21 KFM13770.1 - 7.5e-19 67.6 2.4 7.7e-06 25.9 0.1 3.6 3 0 0 3 3 3 3 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KFM13770.1 - 7.9e-19 67.2 2.1 1.3e-16 60.1 0.5 3.4 3 0 0 3 3 3 2 twin BRCT domain Fibrinogen_C PF00147.13 KFM13771.1 - 4.9e-66 222.7 7.4 8.3e-66 221.9 5.2 1.4 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain SlyX PF04102.7 KFM13771.1 - 0.038 14.3 24.0 0.076 13.4 5.1 3.0 1 1 2 3 3 3 0 SlyX DivIC PF04977.10 KFM13771.1 - 0.17 11.4 18.6 0.03 13.8 2.7 3.5 1 1 1 3 3 3 0 Septum formation initiator V_ATPase_I PF01496.14 KFM13771.1 - 0.29 8.9 13.1 0.42 8.3 9.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4239 PF14023.1 KFM13771.1 - 0.79 9.0 7.8 1.3 8.3 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Phage_lysis PF03245.8 KFM13771.1 - 4.7 7.2 13.3 0.12 12.3 3.4 2.2 1 1 1 2 2 2 0 Bacteriophage Rz lysis protein CUB PF00431.15 KFM13774.1 - 1e-15 57.7 0.0 1.5e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 CUB domain Sushi PF00084.15 KFM13774.1 - 1.2e-08 35.2 0.1 2.1e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 Sushi domain (SCR repeat) CUB PF00431.15 KFM13775.1 - 1e-281 913.9 0.0 1.7e-27 95.6 0.0 12.3 12 0 0 12 12 12 12 CUB domain Sushi PF00084.15 KFM13775.1 - 4.1e-247 798.8 176.8 2.2e-11 43.9 0.9 27.8 27 0 0 27 27 27 27 Sushi domain (SCR repeat) CUB_2 PF02408.15 KFM13775.1 - 9.9e-22 76.7 9.6 0.0033 16.9 0.0 10.8 12 0 0 12 12 12 7 CUB-like domain bZIP_1 PF00170.16 KFM13776.1 - 4e-13 49.0 9.1 6.3e-13 48.4 6.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFM13776.1 - 2.1e-11 43.4 7.7 3.8e-11 42.6 5.3 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KFM13776.1 - 1.5e-05 25.2 5.1 4.5e-05 23.6 3.5 1.8 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF904 PF06005.7 KFM13776.1 - 0.0064 16.7 0.3 0.012 15.9 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF904) DUF1843 PF08898.5 KFM13776.1 - 0.12 12.4 1.3 0.43 10.6 0.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) DivIC PF04977.10 KFM13776.1 - 0.19 11.2 2.9 0.33 10.4 2.0 1.3 1 0 0 1 1 1 0 Septum formation initiator HALZ PF02183.13 KFM13776.1 - 0.72 9.6 4.4 1.4 8.7 3.0 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Shugoshin_N PF07558.6 KFM13776.1 - 0.91 9.2 5.7 2.1 8.0 2.8 2.3 1 1 1 2 2 2 0 Shugoshin N-terminal coiled-coil region RhoGAP PF00620.22 KFM13777.1 - 5.3e-50 168.9 0.0 1.1e-49 167.9 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.17 KFM13777.1 - 7.9e-16 57.5 7.2 1.3e-15 56.8 5.0 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH2 PF00017.19 KFM13777.1 - 3.1e-12 46.1 0.0 9.6e-12 44.5 0.0 1.9 2 0 0 2 2 2 1 SH2 domain zf-RING-like PF08746.6 KFM13777.1 - 0.0033 17.4 4.5 0.0071 16.3 3.1 1.6 1 0 0 1 1 1 1 RING-like domain PHD_2 PF13831.1 KFM13777.1 - 0.042 13.1 1.9 0.09 12.1 1.3 1.5 1 0 0 1 1 1 0 PHD-finger FYVE_2 PF02318.11 KFM13777.1 - 0.43 10.4 7.7 0.55 10.1 4.5 1.8 1 1 0 1 1 1 0 FYVE-type zinc finger WH2 PF02205.15 KFM13778.1 - 1.8e-10 40.0 0.6 4.4e-10 38.8 0.4 1.8 1 0 0 1 1 1 1 WH2 motif Metal_resist PF13801.1 KFM13778.1 - 5.7 6.9 7.2 8.8 6.3 0.3 3.0 2 0 0 2 2 2 0 Heavy-metal resistance Peptidase_C69 PF03577.10 KFM13779.1 - 1.9e-09 36.8 0.0 2.7e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C69 AAT PF03417.11 KFM13779.1 - 0.044 13.2 0.0 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase FKBP_C PF00254.23 KFM13780.1 - 7.1e-28 96.4 0.0 1.2e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_7 PF13499.1 KFM13780.1 - 6.4e-09 35.8 0.7 1.1e-08 35.1 0.5 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KFM13780.1 - 1.1e-06 27.4 5.1 0.014 14.6 1.0 2.9 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.1 KFM13780.1 - 0.00012 21.2 4.2 0.12 11.7 0.9 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KFM13780.1 - 0.00023 20.8 2.9 0.52 10.3 0.6 2.8 2 0 0 2 2 2 2 EF-hand domain GLTP PF08718.6 KFM13781.1 - 1.3e-42 145.3 0.1 3.1e-42 144.1 0.0 1.7 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) PH PF00169.24 KFM13781.1 - 3.9e-07 30.2 0.0 3e-06 27.3 0.0 2.5 2 1 0 2 2 2 1 PH domain PH_8 PF15409.1 KFM13781.1 - 5.9e-05 23.0 0.0 0.00012 22.0 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 KFM13781.1 - 0.0052 17.0 0.0 0.027 14.7 0.0 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain Collagen PF01391.13 KFM13782.1 - 1.1e-28 98.4 96.5 6.6e-10 38.3 19.4 4.5 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) DUF4215 PF13948.1 KFM13782.1 - 8.9e-05 22.6 6.2 8.9e-05 22.6 4.3 3.2 2 1 1 3 3 3 1 Domain of unknown function (DUF4215) TPP_enzyme_M PF00205.17 KFM13783.1 - 4.6e-31 107.3 0.0 1.9e-30 105.4 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.13 KFM13783.1 - 9.2e-29 100.1 0.0 1e-26 93.4 0.0 2.5 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KFM13783.1 - 2.3e-28 98.7 0.0 5.1e-28 97.5 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 KFM13783.1 - 0.22 10.4 0.0 0.4 9.5 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase CN_hydrolase PF00795.17 KFM13784.1 - 5.5e-13 48.6 0.0 9.2e-13 47.9 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Ank_2 PF12796.2 KFM13785.1 - 7e-196 635.2 52.4 2.5e-22 79.0 0.1 13.8 2 2 9 13 13 13 13 Ankyrin repeats (3 copies) Ank PF00023.25 KFM13785.1 - 1.3e-194 621.1 74.7 8.1e-11 41.1 0.1 28.1 28 0 0 28 28 28 27 Ankyrin repeat Ank_4 PF13637.1 KFM13785.1 - 5.9e-159 514.0 48.8 1.4e-14 54.1 0.2 21.1 7 4 16 23 23 23 23 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFM13785.1 - 5.4e-143 461.8 63.3 3e-11 43.1 0.2 22.4 7 5 16 23 23 23 21 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFM13785.1 - 2.8e-126 398.5 63.1 1.1e-07 31.4 0.1 28.4 29 0 0 29 29 29 26 Ankyrin repeat NAD_binding_1 PF00175.16 KFM13786.1 - 1.2e-13 51.5 0.0 2e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KFM13786.1 - 1.1e-07 31.8 0.1 2.5e-06 27.4 0.0 2.4 2 1 1 3 3 3 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.19 KFM13786.1 - 0.0073 16.4 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Raftlin PF15250.1 KFM13787.1 - 3.1e-198 658.9 2.2 3.8e-198 658.6 1.5 1.1 1 0 0 1 1 1 1 Raftlin DUF4177 PF13783.1 KFM13787.1 - 0.0066 16.0 0.0 0.5 10.0 0.0 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4177) PilO PF04350.8 KFM13787.1 - 0.13 12.1 2.7 0.27 11.0 0.0 2.3 2 0 0 2 2 2 0 Pilus assembly protein, PilO RRM_1 PF00076.17 KFM13788.1 - 9.7e-15 53.9 0.5 1.5e-14 53.3 0.4 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFM13788.1 - 3.7e-13 49.2 0.2 5.8e-13 48.6 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFM13788.1 - 4.5e-06 26.4 0.1 9.1e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PI-PLC-X PF00388.14 KFM13789.1 - 1.4e-59 199.6 0.1 3.4e-59 198.4 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KFM13789.1 - 2.9e-43 146.5 0.3 9.6e-43 144.9 0.2 2.0 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 KFM13789.1 - 5.4e-26 90.4 0.2 1.2e-25 89.2 0.1 1.7 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 KFM13789.1 - 8.2e-17 60.8 0.0 1.7e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 C2 domain Mcp5_PH PF12814.2 KFM13789.1 - 2.3e-05 24.3 0.0 5.5e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.24 KFM13789.1 - 0.00032 20.8 0.1 0.0013 18.9 0.0 2.1 2 0 0 2 2 2 1 PH domain RabGAP-TBC PF00566.13 KFM13790.1 - 9.6e-29 100.3 13.1 1.5e-27 96.4 9.0 2.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain CUT PF02376.10 KFM13791.1 - 2.3e-52 174.7 11.3 8.7e-28 95.9 0.2 4.4 4 1 1 5 5 5 2 CUT domain Homeobox PF00046.24 KFM13791.1 - 5.6e-08 32.2 0.0 1.4e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Homeobox domain HTH_3 PF01381.17 KFM13791.1 - 0.05 13.4 0.6 0.45 10.3 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix RuvA_C PF07499.8 KFM13791.1 - 0.063 13.4 0.1 0.38 10.9 0.1 2.3 2 0 0 2 2 2 0 RuvA, C-terminal domain Ras PF00071.17 KFM13792.1 - 2.6e-63 212.2 0.3 3e-63 212.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM13792.1 - 4.3e-21 75.5 0.0 7.7e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM13792.1 - 7.9e-13 48.0 0.0 9.7e-13 47.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFM13792.1 - 2.9e-06 26.6 0.1 3.7e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFM13792.1 - 8.6e-05 22.0 0.1 0.0002 20.8 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFM13792.1 - 0.00015 21.6 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KFM13792.1 - 0.064 12.4 0.1 0.17 11.0 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 PP2C PF00481.16 KFM13793.1 - 6.6e-29 101.0 1.0 6.1e-24 84.8 0.0 3.2 3 0 0 3 3 3 2 Protein phosphatase 2C PCAF_N PF06466.6 KFM13795.1 - 1.9e-132 440.2 0.7 2.8e-132 439.6 0.5 1.3 1 0 0 1 1 1 1 PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain PF00439.20 KFM13795.1 - 8.7e-27 92.8 0.3 2e-26 91.6 0.2 1.7 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 KFM13795.1 - 3.8e-11 42.9 0.3 8.8e-11 41.8 0.2 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFM13795.1 - 6.4e-09 35.7 0.1 1.7e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family zf-met PF12874.2 KFM13796.1 - 2.8e-22 78.1 16.9 1.1e-08 34.9 1.8 3.6 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFM13796.1 - 2.8e-18 65.4 15.3 1.4e-07 31.4 1.9 3.3 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFM13796.1 - 6.9e-08 32.5 6.0 0.013 15.5 0.1 3.2 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.7 KFM13796.1 - 1.1e-06 28.0 6.6 0.049 13.1 0.0 3.3 3 0 0 3 3 3 3 U1 zinc finger AKAP95 PF04988.7 KFM13796.1 - 1.8e-06 27.8 9.0 0.11 12.2 0.6 3.2 3 0 0 3 3 3 3 A-kinase anchoring protein 95 (AKAP95) OrfB_Zn_ribbon PF07282.6 KFM13796.1 - 0.0023 17.5 5.8 0.13 11.9 0.5 3.5 3 0 0 3 3 3 1 Putative transposase DNA-binding domain zf-C2H2_4 PF13894.1 KFM13796.1 - 0.0061 16.8 9.0 1.7 9.1 1.0 3.6 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.21 KFM13796.1 - 0.011 16.0 11.0 1.1 9.7 1.4 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-DBF PF07535.7 KFM13796.1 - 0.024 14.3 7.2 0.086 12.5 0.8 3.1 3 0 0 3 3 3 0 DBF zinc finger DUF3449 PF11931.3 KFM13796.1 - 0.12 11.8 8.4 1.1 8.7 0.8 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3449) zinc-ribbons_6 PF07191.7 KFM13796.1 - 0.6 9.9 5.8 8.5 6.2 0.2 3.1 3 0 0 3 3 3 0 zinc-ribbons TFIIA PF03153.8 KFM13796.1 - 0.77 9.5 8.6 0.93 9.3 5.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF493 PF04359.9 KFM13796.1 - 1.9 8.8 4.4 1.6 9.1 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF493) zf-met PF12874.2 KFM13797.1 - 1.8e-08 34.2 0.6 3.8e-08 33.2 0.4 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFM13797.1 - 3.5e-06 26.9 0.4 3.5e-06 26.9 0.3 1.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding UQ_con PF00179.21 KFM13798.1 - 4.6e-43 146.0 0.0 5e-43 145.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFM13798.1 - 2.9e-05 23.8 0.0 3.4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KFM13798.1 - 0.0028 17.5 0.0 0.0037 17.1 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KFM13798.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 UEV domain UQ_con PF00179.21 KFM13799.1 - 6.1e-43 145.6 0.0 6.7e-43 145.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFM13799.1 - 6.4e-05 22.7 0.0 7.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KFM13799.1 - 0.0036 17.1 0.0 0.0049 16.7 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KFM13799.1 - 0.085 12.5 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 UEV domain Ras PF00071.17 KFM13800.1 - 2.6e-26 91.9 0.4 2.9e-26 91.7 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM13800.1 - 1.8e-17 63.9 0.1 2.8e-17 63.3 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFM13800.1 - 5e-09 35.6 0.3 6.5e-09 35.2 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFM13800.1 - 0.00035 20.5 0.0 0.00054 19.8 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFM13800.1 - 0.00078 18.9 1.4 0.084 12.2 0.9 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.1 KFM13800.1 - 0.0012 18.7 0.2 0.0037 17.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain Dynamin_N PF00350.18 KFM13800.1 - 0.026 14.3 0.4 0.24 11.1 0.3 2.5 1 1 0 1 1 1 0 Dynamin family FeoB_N PF02421.13 KFM13800.1 - 0.059 12.6 0.1 0.2 10.9 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA PF00004.24 KFM13800.1 - 0.14 12.3 0.3 1.8 8.7 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ribosomal_L15e PF00827.12 KFM13801.1 - 3.1e-98 326.9 5.7 3.6e-98 326.7 4.0 1.0 1 0 0 1 1 1 1 Ribosomal L15 Hormone_recep PF00104.25 KFM13802.1 - 7e-33 113.4 0.1 7e-33 113.4 0.0 2.0 3 0 0 3 3 3 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFM13802.1 - 2.5e-31 107.6 15.9 6.5e-31 106.3 11.0 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) zf-C4 PF00105.13 KFM13803.1 - 1.7e-30 105.0 15.9 3.2e-30 104.1 11.0 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 KFM13803.1 - 1.5e-21 76.4 0.0 2.6e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Class_IIIsignal PF04021.7 KFM13804.1 - 0.37 10.5 0.1 0.37 10.5 0.1 2.1 2 0 0 2 2 2 0 Class III signal peptide zf-C4 PF00105.13 KFM13805.1 - 3.4e-34 116.8 16.3 4e-34 116.6 11.3 1.0 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 KFM13806.1 - 8.5e-21 74.0 0.0 1.4e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor DNA_topoisoIV PF00521.15 KFM13807.1 - 3.9e-132 441.1 0.3 6.8e-132 440.3 0.0 1.6 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 KFM13807.1 - 3.5e-35 120.7 1.3 9.8e-35 119.3 0.9 1.8 1 0 0 1 1 1 1 DNA gyrase B DTHCT PF08070.6 KFM13807.1 - 3.7e-32 110.8 16.2 3.7e-32 110.8 11.2 5.8 4 1 1 6 6 6 1 DTHCT (NUC029) region Toprim PF01751.17 KFM13807.1 - 6.3e-15 54.9 0.1 3.8e-14 52.4 0.0 2.4 2 0 0 2 2 2 1 Toprim domain HATPase_c PF02518.21 KFM13807.1 - 1.1e-08 34.7 0.0 3.6e-08 33.0 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Transglut_core PF01841.14 KFM13808.1 - 2e-14 53.7 0.7 4.7e-14 52.5 0.5 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily PUB PF09409.5 KFM13808.1 - 2.1e-14 53.0 0.8 1.1e-13 50.6 0.0 2.6 2 0 0 2 2 2 1 PUB domain Rad4 PF03835.10 KFM13808.1 - 1e-10 41.1 0.9 1.9e-10 40.3 0.6 1.3 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain DUF750 PF04721.12 KFM13808.1 - 1.4e-07 31.4 1.3 3.8e-07 29.9 0.9 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF750) Terminase_1 PF03354.10 KFM13808.1 - 0.03 12.7 0.0 1.6 7.0 0.0 2.1 2 0 0 2 2 2 0 Phage Terminase ketoacyl-synt PF00109.21 KFM13809.1 - 9.5e-53 179.2 2.8 9.5e-53 179.2 1.9 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KFM13809.1 - 8.5e-37 125.6 0.9 1.5e-36 124.8 0.2 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 KFM13809.1 - 2.6e-05 23.3 0.0 5.8e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain LRR_8 PF13855.1 KFM13810.1 - 3.5e-16 58.7 5.5 5.9e-11 41.9 0.1 3.0 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 KFM13810.1 - 4.4e-11 41.2 6.9 0.0034 17.2 0.2 5.0 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_4 PF12799.2 KFM13810.1 - 1e-10 40.9 6.6 5.6e-07 29.0 0.3 3.3 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRRNT PF01462.13 KFM13810.1 - 6.6e-09 35.0 2.8 6.6e-09 35.0 2.0 2.1 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_5 PF13306.1 KFM13810.1 - 2.9e-06 27.0 0.1 4.6e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_7 PF13504.1 KFM13810.1 - 1.2e-05 24.7 3.9 2.3 8.7 0.0 5.1 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 KFM13810.1 - 1.5e-05 24.5 1.4 0.59 10.3 0.0 4.0 3 0 0 3 3 3 2 Leucine Rich repeat Pkinase PF00069.20 KFM13812.1 - 5.8e-31 107.5 1.4 1.1e-30 106.6 1.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM13812.1 - 5e-22 78.2 0.2 8.4e-22 77.4 0.2 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFM13812.1 - 0.00019 21.2 0.1 0.0021 17.8 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KFM13812.1 - 0.0003 20.1 0.3 0.0006 19.2 0.2 1.6 1 0 0 1 1 1 1 RIO1 family Arm PF00514.18 KFM13812.1 - 0.0035 17.1 7.6 0.084 12.7 0.2 4.4 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat HCO3_cotransp PF00955.16 KFM13813.1 - 5.4e-246 817.1 9.6 6.7e-246 816.8 6.7 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.8 KFM13813.1 - 8.9e-106 353.1 0.0 1.5e-105 352.3 0.0 1.4 1 0 0 1 1 1 1 Band 3 cytoplasmic domain Stm1_N PF09598.5 KFM13813.1 - 0.65 10.7 2.7 0.49 11.1 0.1 2.1 2 0 0 2 2 2 0 Stm1 T-box PF00907.17 KFM13814.1 - 1.5e-66 223.3 0.4 2.1e-66 222.9 0.3 1.2 1 0 0 1 1 1 1 T-box Cmc1 PF08583.5 KFM13815.1 - 1.2e-17 63.4 5.1 1.5e-17 63.0 3.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Colipase PF01114.13 KFM13815.1 - 0.014 14.8 1.4 0.021 14.2 1.0 1.3 1 0 0 1 1 1 0 Colipase, N-terminal domain Tmemb_18A PF09771.4 KFM13815.1 - 0.026 14.4 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 188 CHCH PF06747.8 KFM13815.1 - 0.77 9.7 9.1 3.9 7.5 0.1 2.6 3 0 0 3 3 3 0 CHCH domain NDUF_B7 PF05676.8 KFM13815.1 - 2.8 7.4 6.8 0.5 9.8 1.4 1.9 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) ecTbetaR2 PF08917.5 KFM13816.1 - 1.2e-50 170.2 16.7 3.9e-50 168.5 11.6 1.9 1 0 0 1 1 1 1 Transforming growth factor beta receptor 2 ectodomain Pkinase PF00069.20 KFM13816.1 - 1.3e-49 168.6 0.1 2.6e-49 167.6 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM13816.1 - 1e-35 123.0 0.0 1.8e-35 122.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase TMEM154 PF15102.1 KFM13816.1 - 0.017 14.8 0.2 0.043 13.5 0.1 1.6 1 0 0 1 1 1 0 TMEM154 protein family DUF4448 PF14610.1 KFM13816.1 - 0.043 13.2 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) APH PF01636.18 KFM13816.1 - 0.052 13.2 0.1 0.083 12.5 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family 7tm_1 PF00001.16 KFM13816.1 - 0.1 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Pyridoxal_deC PF00282.14 KFM13817.1 - 7.3e-113 376.7 0.0 8.4e-113 376.5 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KFM13817.1 - 4.8e-06 25.5 0.0 2.7e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KFM13817.1 - 9.6e-05 21.6 0.0 0.00012 21.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase SLA_LP_auto_ag PF05889.8 KFM13817.1 - 0.032 12.7 0.0 0.05 12.0 0.0 1.3 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) STT3 PF02516.9 KFM13818.1 - 7.2e-112 374.8 37.8 4.4e-111 372.2 26.2 1.9 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit Oxysterol_BP PF01237.13 KFM13819.1 - 1.3e-72 244.3 0.1 3.7e-72 242.7 0.1 1.7 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.1 KFM13819.1 - 7.8e-08 32.2 0.0 1.4e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KFM13819.1 - 0.00025 21.1 0.0 0.00092 19.3 0.0 2.0 2 0 0 2 2 2 1 PH domain PH_6 PF15406.1 KFM13819.1 - 0.028 14.4 0.0 0.081 12.9 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain NAD_Gly3P_dh_C PF07479.9 KFM13820.1 - 8.8e-57 191.0 0.2 1.4e-56 190.3 0.2 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 KFM13820.1 - 2e-53 180.3 0.7 3.2e-53 179.6 0.2 1.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 KFM13820.1 - 0.00083 19.7 0.4 0.038 14.4 0.3 2.8 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent MARVEL PF01284.18 KFM13821.1 - 1.6e-15 57.1 19.2 1.9e-15 56.9 13.3 1.0 1 0 0 1 1 1 1 Membrane-associating domain SUR7 PF06687.7 KFM13821.1 - 1.2 8.6 11.6 1.7 8.1 7.7 1.5 1 1 0 1 1 1 0 SUR7/PalI family EmrE PF13536.1 KFM13821.1 - 1.9 8.7 15.1 1.5 9.0 0.2 2.1 1 1 1 2 2 2 0 Multidrug resistance efflux transporter NfeD PF01957.13 KFM13821.1 - 2.2 8.3 6.9 2.1 8.4 4.2 1.4 1 1 0 1 1 1 0 NfeD-like C-terminal, partner-binding MARVEL PF01284.18 KFM13822.1 - 1.9e-08 34.2 17.4 4e-08 33.1 12.1 1.5 1 1 0 1 1 1 1 Membrane-associating domain Tmemb_14 PF03647.8 KFM13822.1 - 0.47 10.8 6.2 0.19 12.1 2.4 1.7 1 1 1 2 2 2 0 Transmembrane proteins 14C DUF3147 PF11345.3 KFM13822.1 - 1.9 8.5 8.6 0.43 10.6 1.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3147) RseC_MucC PF04246.7 KFM13822.1 - 2.2 7.8 5.6 0.62 9.6 1.7 1.6 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF1700 PF08006.6 KFM13822.1 - 4.2 6.6 9.3 5.3 6.3 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Tic20 PF09685.5 KFM13822.1 - 7.1 6.6 14.8 66 3.5 10.2 2.0 1 1 0 1 1 1 0 Tic20-like protein DLIC PF05783.6 KFM13824.1 - 2.3e-233 775.1 0.0 2.6e-233 774.8 0.0 1.0 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) Miro PF08477.8 KFM13824.1 - 0.0051 17.2 0.5 0.19 12.2 0.0 2.8 3 0 0 3 3 3 1 Miro-like protein GTP_EFTU PF00009.22 KFM13824.1 - 0.069 12.5 0.5 0.33 10.3 0.0 2.2 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain TPR_1 PF00515.23 KFM13825.1 - 5.7e-15 54.1 15.4 1.8e-05 24.1 0.1 7.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 KFM13825.1 - 1.1e-14 53.8 20.3 0.00034 20.1 0.1 7.1 7 0 0 7 7 7 5 TPR repeat TPR_2 PF07719.12 KFM13825.1 - 5.4e-14 50.9 25.0 0.00078 19.1 0.0 9.0 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFM13825.1 - 3.6e-12 46.0 17.3 0.00092 19.1 0.0 6.4 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFM13825.1 - 5.2e-09 36.5 0.5 5.8 7.7 0.0 6.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFM13825.1 - 1.1e-07 32.0 15.2 1.4 9.3 0.4 8.7 8 3 2 10 10 10 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFM13825.1 - 4.2e-07 29.6 6.1 1.6 9.1 0.0 7.3 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFM13825.1 - 1.4e-06 28.4 4.6 18 6.3 0.0 8.3 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFM13825.1 - 2.7e-05 23.6 12.1 0.13 12.1 0.0 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFM13825.1 - 2.8e-05 23.5 3.0 0.013 15.2 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 KFM13825.1 - 3.4e-05 23.9 23.2 2.9 8.1 0.5 7.4 4 2 4 8 8 8 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 KFM13825.1 - 0.00016 21.4 0.5 1 9.3 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat BLOC1_2 PF10046.4 KFM13825.1 - 0.0028 17.7 3.5 0.017 15.2 2.4 2.4 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_6 PF13174.1 KFM13825.1 - 0.042 14.3 4.6 21 5.8 0.0 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat NHL PF01436.16 KFM13826.1 - 6.1e-55 180.5 14.6 3.6e-10 39.2 0.0 6.6 6 0 0 6 6 6 6 NHL repeat Filamin PF00630.14 KFM13826.1 - 1.8e-18 66.9 0.0 8.8e-18 64.7 0.0 2.1 2 0 0 2 2 2 1 Filamin/ABP280 repeat SGL PF08450.7 KFM13826.1 - 1.9e-10 40.5 0.6 0.017 14.5 0.0 5.7 2 1 4 6 6 6 3 SMP-30/Gluconolaconase/LRE-like region zf-B_box PF00643.19 KFM13826.1 - 3.3e-06 26.8 2.8 3.3e-06 26.8 2.0 1.9 2 0 0 2 2 2 1 B-box zinc finger zf-UBR PF02207.15 KFM13826.1 - 0.16 11.6 6.2 0.14 11.9 1.0 2.7 3 0 0 3 3 3 0 Putative zinc finger in N-recognin (UBR box) potato_inhibit PF00280.13 KFM13826.1 - 0.34 11.0 4.3 64 3.7 0.1 4.7 5 0 0 5 5 5 0 Potato inhibitor I family YlbD_coat PF14071.1 KFM13826.1 - 0.89 9.6 3.9 1.9 8.5 2.7 1.5 1 1 0 1 1 1 0 Putative coat protein Atg14 PF10186.4 KFM13826.1 - 2.9 6.7 9.8 4.5 6.1 6.8 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4461 PF14688.1 KFM13827.1 - 1.9e-110 369.1 2.2 2.6e-110 368.6 1.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4461) DUF4460 PF14687.1 KFM13827.1 - 2.5e-33 114.1 0.1 6.6e-33 112.8 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4460) VWD PF00094.20 KFM13828.1 - 6.8e-31 107.5 2.9 6.8e-31 107.5 2.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type D domain C8 PF08742.6 KFM13828.1 - 2.9e-22 78.6 15.7 2.9e-22 78.6 10.9 2.4 2 0 0 2 2 2 1 C8 domain TIL PF01826.12 KFM13828.1 - 5.2e-05 23.2 3.9 5.2e-05 23.2 2.7 4.8 4 1 0 4 4 4 1 Trypsin Inhibitor like cysteine rich domain VWC PF00093.13 KFM13828.1 - 7.7e-05 22.7 10.2 7.7e-05 22.7 7.0 4.4 3 2 1 4 4 4 1 von Willebrand factor type C domain Pacifastin_I PF05375.8 KFM13828.1 - 0.0029 17.0 11.9 0.0029 17.0 8.2 3.5 2 1 0 2 2 2 1 Pacifastin inhibitor (LCMII) Glyco_hydro_59 PF02057.10 KFM13828.1 - 0.069 11.2 0.1 0.095 10.7 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 59 CUE PF02845.11 KFM13829.1 - 4.5e-16 57.9 0.2 8.7e-16 57.0 0.1 1.5 1 0 0 1 1 1 1 CUE domain C2 PF00168.25 KFM13829.1 - 8.9e-10 38.2 0.0 1.3e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 C2 domain UBA PF00627.26 KFM13829.1 - 0.0014 18.3 0.1 0.003 17.3 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Mob1_phocein PF03637.12 KFM13830.1 - 3e-59 199.6 4.9 3.8e-59 199.2 3.4 1.0 1 0 0 1 1 1 1 Mob1/phocein family DSPc PF00782.15 KFM13831.1 - 9.9e-44 148.1 0.0 1.5e-43 147.5 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.15 KFM13831.1 - 1.5e-11 44.5 0.0 1.9e-10 41.0 0.0 2.2 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.22 KFM13831.1 - 0.00019 20.8 0.0 0.00031 20.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KFM13831.1 - 0.01 15.8 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Dispanin PF04505.7 KFM13832.1 - 2.2e-21 75.1 0.1 3.4e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Interferon-induced transmembrane protein ScdA_N PF04405.9 KFM13832.1 - 0.062 12.7 0.5 0.26 10.7 0.2 2.0 1 1 1 2 2 2 0 Domain of Unknown function (DUF542) Asp PF00026.18 KFM13833.1 - 1e-127 425.7 0.0 1.2e-127 425.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KFM13833.1 - 6e-10 39.3 0.0 6.8e-09 35.8 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal A1_Propeptide PF07966.7 KFM13833.1 - 1.9e-08 33.7 0.0 1.8e-07 30.7 0.0 2.2 2 0 0 2 2 2 1 A1 Propeptide TAXi_C PF14541.1 KFM13833.1 - 6.3e-06 25.8 0.0 2.5e-05 23.8 0.0 2.0 3 0 0 3 3 3 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 KFM13833.1 - 7e-05 23.2 0.4 0.26 11.8 0.1 3.2 2 1 0 2 2 2 2 Aspartyl protease 5-nucleotidase PF06189.7 KFM13835.1 - 1.4e-84 283.0 0.0 4.1e-83 278.2 0.0 1.8 1 1 1 2 2 2 2 5'-nucleotidase Hydrolase_6 PF13344.1 KFM13835.1 - 0.1 12.5 0.0 7 6.6 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase C2 PF00168.25 KFM13836.1 - 4.5e-50 167.4 4.4 9.7e-25 86.2 0.1 2.2 2 0 0 2 2 2 2 C2 domain DOCK-C2 PF14429.1 KFM13836.1 - 7.5e-06 25.6 0.5 0.0042 16.7 0.0 2.3 2 0 0 2 2 2 2 C2 domain in Dock180 and Zizimin proteins CEP76-C2 PF15627.1 KFM13836.1 - 0.00025 20.5 0.0 0.3 10.5 0.0 2.2 2 0 0 2 2 2 2 CEP76 C2 domain Shisa PF13908.1 KFM13836.1 - 0.0026 17.9 0.0 0.0044 17.2 0.0 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Adeno_E3_CR2 PF02439.10 KFM13836.1 - 0.011 15.2 1.3 0.024 14.1 0.9 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TMEM154 PF15102.1 KFM13836.1 - 0.013 15.1 0.0 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 TMEM154 protein family SIT PF15330.1 KFM13836.1 - 0.027 14.5 0.3 0.062 13.4 0.2 1.6 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Rhabdo_glycop PF00974.13 KFM13836.1 - 0.084 11.0 1.0 0.14 10.3 0.7 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Tweety PF04906.8 KFM13836.1 - 0.1 10.9 2.3 0.17 10.2 1.6 1.2 1 0 0 1 1 1 0 Tweety EphA2_TM PF14575.1 KFM13836.1 - 0.18 12.2 1.9 0.22 11.9 0.3 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Troponin PF00992.15 KFM13837.1 - 1.7e-52 176.9 8.3 1.7e-52 176.9 5.7 1.4 2 0 0 2 2 2 1 Troponin DUF919 PF06034.6 KFM13837.1 - 0.0089 15.6 2.2 0.0089 15.6 1.5 2.5 3 1 0 3 3 3 1 Nucleopolyhedrovirus protein of unknown function (DUF919) DUF2408 PF10303.4 KFM13837.1 - 0.016 15.3 5.1 0.037 14.1 3.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Laminin_II PF06009.7 KFM13837.1 - 0.051 13.3 2.0 0.11 12.2 0.6 2.0 1 1 1 2 2 2 0 Laminin Domain II Erp_C PF06780.6 KFM13837.1 - 0.055 13.3 7.3 0.96 9.2 0.7 2.2 2 0 0 2 2 2 0 Erp protein C-terminus DUF948 PF06103.6 KFM13837.1 - 0.1 12.4 0.1 0.33 10.8 0.0 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) YqgF PF14639.1 KFM13837.1 - 0.2 11.2 1.9 0.48 9.9 0.1 1.9 1 1 1 2 2 2 0 Holliday-junction resolvase-like of SPT6 SICA_beta PF12878.2 KFM13837.1 - 0.42 10.3 4.0 3.4 7.4 1.2 2.2 2 0 0 2 2 2 0 SICA extracellular beta domain SbcD_C PF12320.3 KFM13837.1 - 0.71 9.9 8.3 0.86 9.6 2.8 2.7 2 2 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain V_ATPase_I PF01496.14 KFM13837.1 - 0.72 7.6 3.8 0.35 8.6 0.8 1.5 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family CENP-F_leu_zip PF10473.4 KFM13837.1 - 1 9.2 16.7 0.2 11.5 5.9 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF812 PF05667.6 KFM13837.1 - 1.3 7.4 9.6 0.091 11.2 2.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Tropomyosin_1 PF12718.2 KFM13837.1 - 1.9 8.3 19.2 0.067 13.0 1.4 3.0 3 0 0 3 3 3 0 Tropomyosin like TMF_DNA_bd PF12329.3 KFM13837.1 - 2.1 8.1 15.1 0.14 11.9 2.1 2.8 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding TMPIT PF07851.8 KFM13837.1 - 3 6.8 5.5 1.6 7.7 0.6 2.0 1 1 1 2 2 2 0 TMPIT-like protein Lebercilin PF15619.1 KFM13837.1 - 6.1 6.2 15.9 0.094 12.1 0.7 2.8 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease HAUS-augmin3 PF14932.1 KFM13837.1 - 6.3 5.8 9.9 3 6.9 3.9 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DUF4643 PF15485.1 KFM13838.1 - 3.1e-61 207.3 29.8 3.1e-60 204.1 20.7 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4643) Troponin PF00992.15 KFM13840.1 - 1e-37 129.1 41.6 1.5e-36 125.3 24.4 2.0 2 0 0 2 2 2 2 Troponin Peptidase_S64 PF08192.6 KFM13840.1 - 0.1 10.9 7.2 0.12 10.6 5.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF572 PF04502.8 KFM13840.1 - 0.34 10.0 21.5 0.46 9.6 14.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ribosomal_L23 PF00276.15 KFM13841.1 - 3.7e-10 39.6 0.7 5.3e-10 39.1 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L23 RNA_pol_Rpc4 PF05132.9 KFM13841.1 - 0.24 11.3 1.1 0.26 11.2 0.2 1.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 IGF2_C PF08365.6 KFM13842.1 - 2.3e-29 100.8 4.9 4e-29 100.1 3.4 1.4 1 0 0 1 1 1 1 Insulin-like growth factor II E-peptide Insulin PF00049.13 KFM13842.1 - 4.8e-13 49.7 8.5 1.4e-06 28.9 1.3 2.6 2 1 1 3 3 3 2 Insulin/IGF/Relaxin family Ins_beta PF03488.9 KFM13842.1 - 0.23 11.2 2.6 8.1 6.3 0.1 2.3 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type Insulin PF00049.13 KFM13843.1 - 1.5e-24 86.6 1.5 1.8e-24 86.3 1.0 1.1 1 0 0 1 1 1 1 Insulin/IGF/Relaxin family Ins_beta PF03488.9 KFM13843.1 - 0.016 14.9 5.3 0.37 10.6 0.1 2.2 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type TRM13 PF05206.9 KFM13843.1 - 0.074 12.2 0.5 0.22 10.7 0.3 1.6 1 1 0 1 1 1 0 Methyltransferase TRM13 Biopterin_H PF00351.16 KFM13844.1 - 1.1e-196 652.2 0.6 1.3e-196 651.9 0.4 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase TOH_N PF12549.3 KFM13844.1 - 5.8e-20 70.1 0.6 3.8e-12 45.3 0.2 2.7 2 0 0 2 2 2 2 Tyrosine hydroxylase N terminal DUF4559 PF15112.1 KFM13844.1 - 0.037 13.2 0.0 0.11 11.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) Tetraspannin PF00335.15 KFM13845.1 - 1.7e-16 60.1 1.8 2.2e-16 59.8 1.3 1.1 1 0 0 1 1 1 1 Tetraspanin family Tetraspannin PF00335.15 KFM13846.1 - 3.1e-38 131.2 11.2 3.7e-38 131.0 7.8 1.1 1 0 0 1 1 1 1 Tetraspanin family Cad PF03596.8 KFM13846.1 - 0.089 12.4 0.2 0.089 12.4 0.2 1.9 2 0 0 2 2 2 0 Cadmium resistance transporter Claudin_2 PF13903.1 KFM13846.1 - 0.11 12.2 5.0 0.18 11.4 1.2 2.2 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction TSSC4 PF15264.1 KFM13847.1 - 2.4e-29 102.1 0.1 5.9e-29 100.8 0.0 1.7 1 0 0 1 1 1 1 Tumour suppressing sub-chromosomal transferable candidate 4 Ion_trans PF00520.26 KFM13848.1 - 1.7e-05 24.1 23.2 1.7e-05 24.1 16.1 2.5 2 1 0 2 2 2 1 Ion transport protein Mso1_Sec1_bdg PF14475.1 KFM13848.1 - 0.01 15.1 0.0 0.036 13.4 0.0 1.9 1 0 0 1 1 1 0 Sec1-binding region of Mso1 Ion_trans PF00520.26 KFM13849.1 - 2.6e-24 85.5 8.1 2.6e-24 85.5 5.6 1.8 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 KFM13849.1 - 1.6e-11 43.7 7.0 1.6e-11 43.7 4.8 2.6 2 0 0 2 2 2 1 Ion channel Dispanin PF04505.7 KFM13849.1 - 0.053 13.0 0.8 0.17 11.4 0.0 2.3 2 0 0 2 2 2 0 Interferon-induced transmembrane protein 2TM PF13239.1 KFM13849.1 - 3.7 7.6 8.1 0.44 10.6 1.8 2.3 3 0 0 3 3 3 0 2TM domain MFS_1 PF07690.11 KFM13850.1 - 2.2e-34 118.7 64.7 2.2e-26 92.4 26.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 KFM13850.1 - 2.5e-07 29.2 18.2 7e-06 24.4 3.8 3.0 1 1 2 3 3 3 3 Transmembrane secretion effector PH PF00169.24 KFM13851.1 - 2e-06 27.9 0.1 2.8e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 PH domain NAP PF00956.13 KFM13852.1 - 2.4e-93 311.7 5.4 2.4e-93 311.7 3.8 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) DUF1759 PF03564.10 KFM13852.1 - 0.098 12.4 0.6 11 5.8 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1759) ADSL_C PF10397.4 KFM13852.1 - 0.11 12.5 0.2 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminus tRNA-synt_1e PF01406.14 KFM13853.1 - 2.7e-127 424.0 0.2 2.7e-127 424.0 0.1 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 KFM13853.1 - 3.5e-07 29.2 0.6 0.00016 20.4 0.2 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KFM13853.1 - 0.0011 17.1 2.2 0.0023 16.0 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) GST_C_3 PF14497.1 KFM13853.1 - 0.025 15.0 1.0 0.19 12.1 0.0 3.1 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain TNFR_c6 PF00020.13 KFM13854.1 - 2.2e-08 34.0 27.8 5.9e-08 32.6 6.1 3.4 2 1 0 3 3 3 2 TNFR/NGFR cysteine-rich region Oxysterol_BP PF01237.13 KFM13855.1 - 3.1e-91 305.5 0.1 5.5e-91 304.6 0.0 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein PH PF00169.24 KFM13855.1 - 2.5e-09 37.2 1.5 6.1e-09 36.0 0.0 2.5 2 1 0 2 2 2 1 PH domain Y_phosphatase PF00102.22 KFM13857.1 - 3.2e-87 291.7 0.7 6.6e-87 290.7 0.5 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase fn3 PF00041.16 KFM13857.1 - 1.3e-41 140.5 22.8 7.7e-08 32.3 0.2 7.6 7 1 0 7 7 7 7 Fibronectin type III domain DUF1297 PF06973.7 KFM13857.1 - 3.2e-08 33.0 0.1 0.29 10.4 0.0 4.2 3 1 1 4 4 4 3 Domain of unknown function (DUF1297) PTPlike_phytase PF14566.1 KFM13857.1 - 0.00096 19.2 0.0 0.003 17.6 0.0 1.9 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 KFM13857.1 - 0.0038 17.5 0.1 0.016 15.4 0.0 2.1 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 KFM13857.1 - 0.0039 16.7 0.0 0.015 14.8 0.0 2.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Syndecan PF01034.15 KFM13857.1 - 0.0048 16.5 0.1 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 Syndecan domain DUF2627 PF11118.3 KFM13857.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) IncA PF04156.9 KFM13857.1 - 0.32 10.5 0.0 5 6.6 0.0 2.2 2 0 0 2 2 2 0 IncA protein SKG6 PF08693.5 KFM13857.1 - 1.8 7.9 6.1 5 6.5 4.2 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Y_phosphatase PF00102.22 KFM13858.1 - 1.9e-75 253.2 0.8 3.4e-75 252.4 0.5 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFM13858.1 - 8e-07 28.7 0.0 1.9e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFM13858.1 - 0.00057 20.1 0.0 0.0012 19.1 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KFM13858.1 - 0.028 14.4 0.0 0.098 12.6 0.0 1.8 1 1 1 2 2 2 0 Inositol hexakisphosphate DUF307 PF03733.8 KFM13858.1 - 0.058 13.8 0.8 0.18 12.2 0.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF307) Myotub-related PF06602.9 KFM13858.1 - 0.059 12.1 0.0 0.09 11.5 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DUF3910 PF13049.1 KFM13858.1 - 0.089 12.8 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3910) CPSase_L_D2 PF02786.12 KFM13858.1 - 0.13 11.4 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain YhhN PF07947.9 KFM13859.1 - 9.4e-46 155.5 25.5 9.4e-46 155.5 17.7 1.3 2 0 0 2 2 2 1 YhhN-like protein DUF3816 PF12822.2 KFM13859.1 - 1.8 8.3 12.8 1.1 9.1 7.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) YtpI PF14007.1 KFM13859.1 - 3.1 7.7 10.0 0.38 10.7 0.6 3.0 2 1 0 2 2 2 0 YtpI-like protein UEV PF05743.8 KFM13860.1 - 5.3e-42 142.3 0.1 8.6e-42 141.6 0.1 1.3 1 0 0 1 1 1 1 UEV domain Ldh_1_N PF00056.18 KFM13860.1 - 5.1e-23 81.4 0.5 9.3e-23 80.6 0.3 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KFM13860.1 - 1.3e-14 54.3 0.0 3.1e-14 53.0 0.0 1.7 1 1 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain F420_oxidored PF03807.12 KFM13860.1 - 0.067 13.6 1.7 0.11 12.9 0.3 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 KFM13860.1 - 0.12 12.0 0.6 0.21 11.1 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UEV PF05743.8 KFM13861.1 - 8.6e-48 161.0 1.4 1.1e-46 157.4 0.2 2.3 2 0 0 2 2 2 1 UEV domain Vps23_core PF09454.5 KFM13861.1 - 1.3e-28 98.3 0.2 2.3e-28 97.5 0.1 1.4 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.21 KFM13861.1 - 0.00025 20.4 0.5 0.00025 20.4 0.4 2.3 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme APG6 PF04111.7 KFM13861.1 - 0.0028 16.7 7.4 0.004 16.2 5.1 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 DUF3450 PF11932.3 KFM13861.1 - 0.0049 16.1 6.6 0.0049 16.1 4.6 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) Macoilin PF09726.4 KFM13861.1 - 0.009 14.3 3.8 0.012 13.9 2.6 1.1 1 0 0 1 1 1 1 Transmembrane protein V_ATPase_I PF01496.14 KFM13861.1 - 0.025 12.4 2.4 0.032 12.1 1.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 KFM13861.1 - 0.028 14.0 6.6 0.041 13.4 4.5 1.3 1 0 0 1 1 1 0 IncA protein SlyX PF04102.7 KFM13861.1 - 0.033 14.5 3.9 0.033 14.5 2.7 2.9 2 1 1 3 3 3 0 SlyX TBPIP PF07106.8 KFM13861.1 - 0.05 13.1 7.8 0.081 12.4 5.4 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1640 PF07798.6 KFM13861.1 - 0.051 13.6 8.5 0.047 13.7 5.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) LXG PF04740.7 KFM13861.1 - 0.054 13.2 3.9 0.097 12.4 2.7 1.3 1 0 0 1 1 1 0 LXG domain of WXG superfamily DUF342 PF03961.8 KFM13861.1 - 0.061 11.7 4.9 0.084 11.2 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Spc24 PF08286.6 KFM13861.1 - 0.11 12.1 13.0 0.29 10.8 4.3 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF848 PF05852.6 KFM13861.1 - 0.12 12.1 4.5 0.22 11.3 3.1 1.4 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DUF2317 PF10079.4 KFM13861.1 - 0.17 10.4 4.9 0.26 9.8 3.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Reo_sigmaC PF04582.7 KFM13861.1 - 0.17 11.0 0.3 0.27 10.3 0.2 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Nup88 PF10168.4 KFM13861.1 - 0.18 9.6 3.8 0.27 9.0 2.6 1.1 1 0 0 1 1 1 0 Nuclear pore component DUF1002 PF06207.6 KFM13861.1 - 0.2 10.9 5.7 0.31 10.3 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) Fzo_mitofusin PF04799.8 KFM13861.1 - 0.21 10.9 4.3 0.37 10.1 3.0 1.3 1 0 0 1 1 1 0 fzo-like conserved region Nsp1_C PF05064.8 KFM13861.1 - 0.25 10.9 7.8 0.21 11.2 3.7 2.1 2 1 1 3 3 3 0 Nsp1-like C-terminal region FlxA PF14282.1 KFM13861.1 - 0.38 10.7 4.6 0.65 9.9 3.2 1.3 1 0 0 1 1 1 0 FlxA-like protein Bap31 PF05529.7 KFM13861.1 - 0.41 10.0 5.6 0.67 9.3 3.9 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like HSP70 PF00012.15 KFM13861.1 - 0.47 8.3 5.0 0.58 7.9 3.5 1.1 1 0 0 1 1 1 0 Hsp70 protein DUF641 PF04859.7 KFM13861.1 - 0.6 9.8 5.9 1.2 8.9 4.1 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF724 PF05266.9 KFM13861.1 - 0.88 9.1 8.6 1.4 8.5 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF3552 PF12072.3 KFM13861.1 - 0.9 8.7 12.1 1.4 8.0 8.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Seryl_tRNA_N PF02403.17 KFM13861.1 - 1 9.3 11.0 0.88 9.6 4.9 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.7 KFM13861.1 - 1.4 9.2 5.7 3.6 7.9 2.6 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Prefoldin PF02996.12 KFM13861.1 - 3.3 7.3 10.4 2.8 7.6 1.5 2.3 1 1 1 2 2 2 0 Prefoldin subunit DUF4164 PF13747.1 KFM13861.1 - 4.3 7.5 12.1 2.7 8.1 2.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Prefoldin_2 PF01920.15 KFM13861.1 - 4.7 7.0 15.1 4.4 7.1 2.9 2.4 1 1 1 2 2 2 0 Prefoldin subunit Viral_P18 PF04521.8 KFM13861.1 - 6.7 6.1 13.0 0.35 10.3 2.1 2.7 2 1 1 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein DUF972 PF06156.8 KFM13861.1 - 8.1 6.8 9.2 22 5.4 6.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Ldh_1_N PF00056.18 KFM13862.1 - 3.8e-48 162.8 0.2 5.5e-48 162.3 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KFM13862.1 - 1.6e-32 112.6 0.0 1.6e-31 109.3 0.0 2.0 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.11 KFM13862.1 - 0.0032 16.8 0.6 0.018 14.3 0.0 2.3 3 0 0 3 3 3 1 Family 4 glycosyl hydrolase BSD PF03909.12 KFM13863.1 - 5.9e-29 99.6 0.8 3e-15 55.7 0.0 2.9 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 KFM13863.1 - 8.7e-22 76.5 0.0 1.5e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain DUF2652 PF10851.3 KFM13863.1 - 0.097 12.6 0.3 8 6.4 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2652) DUF3639 PF12341.3 KFM13864.1 - 0.16 11.9 0.5 4.2 7.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3639) SAA PF00277.13 KFM13865.1 - 3.8e-48 162.0 9.5 4.2e-48 161.9 6.6 1.0 1 0 0 1 1 1 1 Serum amyloid A protein Golgin_A5 PF09787.4 KFM13866.1 - 0.011 14.3 0.4 0.011 14.2 0.3 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 SCRG1 PF15224.1 KFM13866.1 - 0.028 14.2 0.1 0.037 13.8 0.1 1.4 1 0 0 1 1 1 0 Scrapie-responsive protein 1 IKKbetaNEMObind PF12179.3 KFM13866.1 - 0.19 11.5 2.3 0.22 11.3 0.5 1.9 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain Biopterin_H PF00351.16 KFM13867.1 - 1e-187 622.7 0.1 1.3e-187 622.3 0.1 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.20 KFM13867.1 - 3.5e-07 29.5 0.0 8.6e-07 28.3 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.1 KFM13867.1 - 0.43 10.9 2.6 0.31 11.4 0.2 1.9 2 0 0 2 2 2 0 ACT domain RCC1 PF00415.13 KFM13868.1 - 7.9e-52 173.2 19.6 3.8e-12 46.2 0.1 6.9 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KFM13868.1 - 1.2e-28 98.0 36.9 1.9e-09 36.8 0.2 6.9 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Ion_trans PF00520.26 KFM13869.1 - 1.5e-32 112.4 8.3 1.5e-32 112.4 5.7 1.5 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 KFM13869.1 - 1.8e-28 98.6 0.0 4.3e-28 97.3 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.11 KFM13869.1 - 8.9e-11 41.3 2.9 8.9e-11 41.3 2.0 2.5 2 0 0 2 2 2 1 Ion channel DUF202 PF02656.10 KFM13869.1 - 0.66 10.2 4.4 1.3e+02 2.9 0.0 3.5 2 1 0 2 2 2 0 Domain of unknown function (DUF202) PKD_channel PF08016.7 KFM13869.1 - 5.2 5.3 9.2 1.1 7.6 2.4 2.0 1 1 1 2 2 2 0 Polycystin cation channel Basic PF01586.11 KFM13870.1 - 2.6e-30 104.9 2.1 2.6e-30 104.9 1.4 2.1 2 0 0 2 2 2 1 Myogenic Basic domain Myf5 PF12232.3 KFM13870.1 - 2.9e-28 98.2 10.3 7.5e-28 96.9 7.1 1.7 1 0 0 1 1 1 1 Myogenic determination factor 5 HLH PF00010.21 KFM13870.1 - 1.5e-15 56.6 3.5 2.9e-15 55.6 2.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ferritin PF00210.19 KFM13871.1 - 8.3e-15 54.7 0.0 1.1e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain Fibrinogen_aC PF12160.3 KFM13871.1 - 0.045 13.2 0.0 5.6 6.5 0.0 2.6 2 1 0 2 2 2 0 Fibrinogen alpha C domain VWD PF00094.20 KFM13872.1 - 3.7e-69 231.9 9.7 1.1e-34 119.9 0.1 3.8 3 0 0 3 3 3 3 von Willebrand factor type D domain C8 PF08742.6 KFM13872.1 - 1.9e-50 169.0 55.0 7.6e-20 70.9 8.3 9.5 10 1 1 11 11 11 4 C8 domain AbfB PF05270.8 KFM13872.1 - 1.1e-15 57.6 0.3 2.4e-15 56.4 0.2 1.6 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) TIL PF01826.12 KFM13872.1 - 2e-12 47.0 81.4 5e-10 39.3 14.4 16.7 15 2 3 18 18 18 5 Trypsin Inhibitor like cysteine rich domain ABC_membrane PF00664.18 KFM13873.1 - 5.9e-64 216.1 36.4 6.8e-34 117.5 12.2 2.9 3 1 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFM13873.1 - 2e-51 173.8 2.1 1.5e-24 86.8 0.0 3.7 4 0 0 4 4 4 2 ABC transporter SMC_N PF02463.14 KFM13873.1 - 2e-11 43.5 0.0 0.00035 19.8 0.0 3.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KFM13873.1 - 4.1e-08 33.5 2.8 0.17 11.8 0.8 4.4 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KFM13873.1 - 1.6e-07 30.9 0.0 0.00056 19.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 KFM13873.1 - 8.3e-05 21.3 1.1 0.026 13.1 0.0 3.1 3 1 0 3 3 3 1 Predicted ATPase of the ABC class Miro PF08477.8 KFM13873.1 - 0.00012 22.5 0.0 0.41 11.1 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 KFM13873.1 - 0.00023 20.6 0.1 0.13 11.7 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 KFM13873.1 - 0.0011 18.1 0.0 0.024 13.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KFM13873.1 - 0.0015 18.4 0.1 0.22 11.4 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP-synt_ab PF00006.20 KFM13873.1 - 0.0029 17.1 0.1 0.31 10.5 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain T2SE PF00437.15 KFM13873.1 - 0.0063 15.4 0.0 0.83 8.4 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Zeta_toxin PF06414.7 KFM13873.1 - 0.0068 15.5 0.0 0.22 10.6 0.0 2.6 3 0 0 3 3 3 1 Zeta toxin AAA_10 PF12846.2 KFM13873.1 - 0.016 14.6 0.3 2 7.7 0.1 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_22 PF13401.1 KFM13873.1 - 0.028 14.5 0.0 12 6.0 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KFM13873.1 - 0.04 13.8 0.1 0.28 11.1 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain KaiC PF06745.8 KFM13873.1 - 0.046 12.8 0.2 7.1 5.6 0.0 2.5 2 0 0 2 2 2 0 KaiC AAA_23 PF13476.1 KFM13873.1 - 0.069 13.4 8.9 5.9 7.1 4.6 2.9 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 KFM13873.1 - 1.4 8.7 6.9 0.66 9.7 0.7 2.9 2 1 0 2 2 2 0 Dynamin family IRK PF01007.15 KFM13874.1 - 9e-157 521.1 0.1 1.1e-156 520.8 0.1 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 KFM13874.1 - 0.022 14.4 1.9 0.022 14.4 1.3 2.1 2 0 0 2 2 2 0 Ion channel EF-hand_7 PF13499.1 KFM13875.1 - 3.9e-13 49.3 3.5 3.9e-13 49.3 2.4 3.8 4 2 0 4 4 4 1 EF-hand domain pair EF-hand_1 PF00036.27 KFM13875.1 - 1.5e-09 36.4 2.8 0.00024 20.1 0.3 3.7 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 KFM13875.1 - 4.9e-06 25.9 4.2 0.00012 21.6 0.4 3.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 KFM13875.1 - 0.00053 19.2 4.0 0.0055 16.0 0.3 4.2 4 0 0 4 4 4 1 EF hand EF-hand_8 PF13833.1 KFM13875.1 - 1.6 8.3 9.6 3 7.5 0.0 3.9 5 0 0 5 5 5 0 EF-hand domain pair DUF3186 PF11382.3 KFM13875.1 - 9.7 5.2 7.6 18 4.3 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) Ribosomal_S13_N PF08069.7 KFM13876.1 - 1.8e-24 85.3 0.1 4.3e-24 84.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 KFM13876.1 - 5.3e-24 83.8 0.3 1.1e-23 82.7 0.2 1.5 2 0 0 2 2 2 1 Ribosomal protein S15 PAX PF00292.13 KFM13876.1 - 0.026 14.2 0.0 0.063 13.0 0.0 1.6 2 0 0 2 2 2 0 'Paired box' domain SMAP PF15477.1 KFM13877.1 - 2.3e-06 27.7 0.3 2.3e-06 27.7 0.2 2.6 2 1 1 3 3 3 1 Small acidic protein family Nop14 PF04147.7 KFM13877.1 - 0.2 9.5 18.2 0.25 9.2 12.6 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2052 PF09747.4 KFM13877.1 - 0.55 10.1 16.3 0.74 9.7 11.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) NOA36 PF06524.7 KFM13877.1 - 0.71 9.0 11.1 0.86 8.8 7.7 1.2 1 0 0 1 1 1 0 NOA36 protein BUD22 PF09073.5 KFM13877.1 - 0.79 8.7 17.9 0.95 8.4 12.4 1.1 1 0 0 1 1 1 0 BUD22 SMN PF06003.7 KFM13877.1 - 0.81 8.7 6.7 0.95 8.5 4.7 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) RNA_polI_A34 PF08208.6 KFM13877.1 - 0.98 9.0 17.0 0.17 11.5 9.1 1.5 1 1 1 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF572 PF04502.8 KFM13877.1 - 1.4 8.0 16.4 1.6 7.8 11.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) RR_TM4-6 PF06459.7 KFM13877.1 - 1.5 8.6 14.0 1.9 8.3 9.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM60A PF15396.1 KFM13877.1 - 2.1 8.0 6.7 2.5 7.7 4.6 1.1 1 0 0 1 1 1 0 Protein Family FAM60A CDC45 PF02724.9 KFM13877.1 - 3 5.7 15.3 3.4 5.5 10.6 1.1 1 0 0 1 1 1 0 CDC45-like protein FCP1_C PF09309.5 KFM13877.1 - 3.6 6.8 21.8 5 6.3 14.8 1.5 1 1 0 1 1 1 0 FCP1, C-terminal AF-4 PF05110.8 KFM13877.1 - 7.7 4.2 19.3 8.8 4.0 13.4 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DDHD PF02862.12 KFM13877.1 - 8.9 6.0 11.7 12 5.6 8.1 1.2 1 0 0 1 1 1 0 DDHD domain HMG_box PF00505.14 KFM13878.1 - 2.1e-22 79.1 4.3 6.8e-22 77.5 3.0 2.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFM13878.1 - 6.8e-09 35.9 1.0 6.8e-09 35.9 0.7 3.2 3 0 0 3 3 3 1 HMG-box domain AAA_23 PF13476.1 KFM13878.1 - 2.1 8.6 13.6 6.3 7.0 8.4 2.2 2 0 0 2 2 2 0 AAA domain OmpH PF03938.9 KFM13878.1 - 7.5 6.4 25.5 3.2 7.6 0.1 2.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Arm PF00514.18 KFM13880.1 - 0.0011 18.6 12.7 0.0027 17.4 0.2 5.1 5 1 0 5 5 5 2 Armadillo/beta-catenin-like repeat CMS1 PF14617.1 KFM13880.1 - 0.26 10.3 2.0 1.6 7.7 0.0 2.9 4 0 0 4 4 4 0 U3-containing 90S pre-ribosomal complex subunit Yae1_N PF09811.4 KFM13881.1 - 3.8e-12 45.5 31.7 0.0024 17.3 1.7 3.5 2 1 0 2 2 2 2 Essential protein Yae1, N terminal Calc_CGRP_IAPP PF00214.14 KFM13882.1 - 2.1e-45 153.9 0.2 2.3e-45 153.8 0.1 1.0 1 0 0 1 1 1 1 Calcitonin / CGRP / IAPP family DUF1615 PF07759.7 KFM13882.1 - 0.052 12.2 0.0 0.058 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1615) p450 PF00067.17 KFM13883.1 - 2.3e-115 385.7 0.0 2.6e-115 385.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DNA_primase_S PF01896.14 KFM13883.1 - 0.091 12.5 0.0 0.22 11.3 0.0 1.6 1 1 1 2 2 2 0 Eukaryotic and archaeal DNA primase small subunit PDEase_I PF00233.14 KFM13884.1 - 1.6e-47 162.2 0.1 2e-43 148.8 0.0 2.3 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase Sigma70_ner PF04546.8 KFM13884.1 - 0.00027 20.6 2.1 0.00056 19.5 1.5 1.5 1 0 0 1 1 1 1 Sigma-70, non-essential region DUF1129 PF06570.6 KFM13884.1 - 0.52 9.5 3.2 1.7 7.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Proteasome PF00227.21 KFM13885.1 - 3.5e-53 179.7 0.0 4.1e-53 179.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KFM13885.1 - 3.6e-05 22.9 0.3 6.9e-05 22.0 0.2 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Adaptin_N PF01602.15 KFM13886.1 - 5.8e-121 404.3 10.0 8.7e-121 403.8 6.9 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 KFM13886.1 - 1.6e-64 215.4 0.0 3.4e-64 214.4 0.0 1.6 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 KFM13886.1 - 3.3e-62 208.3 0.2 8.3e-62 206.9 0.1 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 KFM13886.1 - 9.3e-11 41.8 5.5 0.00097 19.3 0.0 6.1 3 1 2 5 5 5 2 HEAT repeats HEAT PF02985.17 KFM13886.1 - 8.9e-08 31.5 0.1 0.017 15.1 0.0 4.6 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 KFM13886.1 - 4.9e-06 26.8 0.7 0.041 14.3 0.0 4.9 5 0 0 5 5 5 1 HEAT-like repeat Cnd1 PF12717.2 KFM13886.1 - 6.3e-05 22.8 12.2 0.062 13.1 0.0 4.7 3 2 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 KFM13886.1 - 0.00016 21.3 0.1 2.6 7.9 0.0 4.0 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat MMS19_N PF14500.1 KFM13886.1 - 0.00023 20.5 0.1 0.0016 17.7 0.0 2.4 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II Ras PF00071.17 KFM13887.1 - 1.8e-48 163.9 0.3 2.1e-48 163.7 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFM13887.1 - 5.1e-12 46.3 0.0 1.1e-11 45.2 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 KFM13887.1 - 6.3e-07 29.0 0.0 7.9e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 KFM13887.1 - 4.3e-06 26.0 0.1 4.9e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family ATP_bind_1 PF03029.12 KFM13887.1 - 0.0047 16.4 0.0 0.0059 16.1 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Tub PF01167.13 KFM13888.1 - 1.1e-117 391.3 0.0 1.1e-117 391.3 0.0 2.3 3 1 1 4 4 4 1 Tub family RIC3 PF15361.1 KFM13889.1 - 1.1e-35 123.0 0.1 8.2e-35 120.2 0.0 2.2 2 0 0 2 2 2 1 Resistance to inhibitors of cholinesterase homologue 3 DUF3398 PF11878.3 KFM13889.1 - 0.026 14.3 0.4 0.071 12.9 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3398) IER PF05760.7 KFM13889.1 - 7.6 6.3 10.3 11 5.8 6.9 1.4 1 1 0 1 1 1 0 Immediate early response protein (IER) LIM PF00412.17 KFM13890.1 - 1.8e-30 104.7 22.0 2.4e-15 56.3 5.8 2.0 2 0 0 2 2 2 2 LIM domain C1_4 PF07975.7 KFM13890.1 - 3.9 7.5 22.2 0.36 10.8 4.6 2.5 2 0 0 2 2 2 0 TFIIH C1-like domain Ribosomal_L18e PF00828.14 KFM13891.1 - 3.3e-38 130.9 0.5 4e-38 130.6 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 DUF4537 PF15057.1 KFM13892.1 - 6e-35 119.7 0.0 8.2e-35 119.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) HLH PF00010.21 KFM13893.1 - 1.2e-16 60.0 2.7 1.8e-16 59.5 1.9 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Tmemb_9 PF05434.6 KFM13894.1 - 4.9e-76 253.5 0.6 6e-76 253.2 0.4 1.1 1 0 0 1 1 1 1 TMEM9 Neurensin PF14927.1 KFM13894.1 - 0.064 12.6 0.0 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 Neurensin Asp_protease PF09668.5 KFM13895.1 - 1.2e-10 41.0 0.0 2.2e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KFM13895.1 - 2.8e-09 36.6 0.0 8.1e-09 35.1 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 KFM13895.1 - 1.8e-06 28.3 0.0 5.2e-06 26.8 0.0 1.9 1 1 0 1 1 1 1 Aspartyl protease RVP PF00077.15 KFM13895.1 - 0.071 13.0 0.0 0.19 11.6 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease FXa_inhibition PF14670.1 KFM13896.1 - 3.4e-62 206.2 181.2 1e-11 44.7 7.0 12.5 13 1 0 13 13 13 9 Coagulation Factor Xa inhibitory site cEGF PF12662.2 KFM13896.1 - 1.2e-31 107.9 75.4 9.2e-08 31.5 0.4 10.6 11 0 0 11 11 11 7 Complement Clr-like EGF-like EGF_CA PF07645.10 KFM13896.1 - 1e-25 89.3 165.7 1.9e-07 30.9 3.7 11.8 12 0 0 12 12 12 7 Calcium-binding EGF domain GCC2_GCC3 PF07699.8 KFM13896.1 - 2.4e-23 81.4 43.9 1.5e-12 46.8 1.3 5.6 5 0 0 5 5 5 3 GCC2 and GCC3 EGF PF00008.22 KFM13896.1 - 4.4e-21 74.4 131.4 2.5e-05 24.1 3.3 11.1 10 1 0 10 10 10 9 EGF-like domain EGF_3 PF12947.2 KFM13896.1 - 3.3e-20 71.7 136.7 7.7e-09 35.3 4.8 10.8 9 0 0 9 9 9 7 EGF domain CUB PF00431.15 KFM13896.1 - 1.1e-19 70.4 0.2 4.4e-19 68.5 0.0 2.2 2 0 0 2 2 2 1 CUB domain DENN PF02141.16 KFM13897.1 - 1.4e-60 204.1 5.2 2.5e-60 203.4 3.1 1.8 2 0 0 2 2 2 1 DENN (AEX-3) domain RUN PF02759.14 KFM13897.1 - 1.1e-37 128.7 7.8 1.3e-18 66.9 1.2 2.8 3 0 0 3 3 3 2 RUN domain uDENN PF03456.13 KFM13897.1 - 2.4e-20 72.2 0.6 6.9e-20 70.7 0.1 2.2 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.14 KFM13897.1 - 6.1e-20 71.0 4.5 6.1e-20 71.0 3.1 2.3 2 0 0 2 2 2 1 dDENN domain PLAT PF01477.18 KFM13897.1 - 4.8e-16 59.1 0.0 9.8e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 PLAT/LH2 domain SNARE_assoc PF09335.6 KFM13898.1 - 8.8e-24 84.0 6.2 8.8e-24 84.0 4.3 2.5 3 0 0 3 3 3 1 SNARE associated Golgi protein DUF3357 PF11837.3 KFM13898.1 - 0.085 12.7 0.2 0.39 10.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) IncA PF04156.9 KFM13898.1 - 1.4 8.5 6.0 3.2 7.2 0.0 2.4 3 0 0 3 3 3 0 IncA protein zf-H2C2_2 PF13465.1 KFM13899.1 - 8.2e-43 142.6 55.0 1.9e-09 37.3 0.4 7.7 8 0 0 8 8 7 7 Zinc-finger double domain zf-C2H2 PF00096.21 KFM13899.1 - 1.2e-29 100.7 47.6 4.4e-06 26.7 0.8 7.4 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFM13899.1 - 1e-22 78.7 41.1 0.0025 18.0 0.4 7.3 7 0 0 7 7 7 7 C2H2-type zinc finger CopK PF11525.3 KFM13899.1 - 8.1e-06 25.4 0.3 3.3 7.4 0.0 4.2 2 2 2 4 4 4 2 Copper resistance protein K zf-C2H2_jaz PF12171.3 KFM13899.1 - 0.00042 20.3 33.0 2.2 8.5 0.7 7.7 6 2 1 7 7 7 4 Zinc-finger double-stranded RNA-binding FecR PF04773.8 KFM13899.1 - 0.002 18.3 0.7 0.44 10.8 0.1 3.3 2 1 2 4 4 4 1 FecR protein zf-TRAF PF02176.13 KFM13899.1 - 0.002 18.4 1.3 0.002 18.4 0.9 4.1 1 1 3 4 4 4 1 TRAF-type zinc finger CTP-dep_RFKase PF01982.11 KFM13899.1 - 0.097 12.3 0.6 12 5.5 0.0 3.8 3 1 2 5 5 5 0 Domain of unknown function DUF120 Ogr_Delta PF04606.7 KFM13899.1 - 0.89 9.2 23.3 8.7 6.0 1.0 6.1 4 2 2 6 6 6 0 Ogr/Delta-like zinc finger zf-met PF12874.2 KFM13899.1 - 5.2 7.4 23.5 18 5.6 0.0 6.7 7 0 0 7 7 7 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFM13899.1 - 5.5 7.0 18.1 0.11 12.4 0.4 5.1 7 0 0 7 7 7 0 C2H2-type zinc finger Pkinase PF00069.20 KFM13900.1 - 1.3e-47 162.1 0.0 1.8e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM13900.1 - 6.8e-22 77.7 0.0 8.5e-22 77.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase A_deaminase PF00962.17 KFM13901.1 - 2.9e-125 417.5 0.3 4.2e-125 417.0 0.2 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase zf-C3HC4_3 PF13920.1 KFM13902.1 - 9.3e-11 41.2 10.7 1.5e-10 40.5 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFM13902.1 - 1.1e-10 41.1 13.3 2.1e-10 40.2 9.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFM13902.1 - 2.2e-07 30.7 14.0 4.1e-07 29.9 9.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM13902.1 - 1.1e-06 28.1 12.5 2.1e-06 27.2 8.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM13902.1 - 4.5e-05 23.0 14.1 0.00025 20.6 9.6 2.1 1 1 1 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.1 KFM13902.1 - 9.4e-05 21.8 5.7 0.00017 21.0 4.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 KFM13902.1 - 0.00047 19.8 7.0 0.00082 19.0 3.0 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 KFM13902.1 - 0.0015 18.6 14.8 0.0099 15.9 10.2 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 KFM13902.1 - 0.035 13.9 12.6 0.079 12.8 8.4 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Sulfotransfer_2 PF03567.9 KFM13902.1 - 0.071 12.7 0.1 0.13 11.9 0.0 1.5 2 0 0 2 2 2 0 Sulfotransferase family zf-RING_4 PF14570.1 KFM13902.1 - 0.29 10.7 11.8 0.61 9.7 8.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 KFM13902.1 - 0.4 10.5 9.3 0.82 9.5 5.9 1.8 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rad50_zn_hook PF04423.9 KFM13902.1 - 1.2 8.6 7.8 0.49 9.9 0.3 3.3 3 0 0 3 3 3 0 Rad50 zinc hook motif Xlink PF00193.12 KFM13903.1 - 1.7e-19 69.6 0.1 3e-19 68.9 0.1 1.4 1 0 0 1 1 1 1 Extracellular link domain MGC-24 PF05283.6 KFM13903.1 - 0.0024 17.7 1.3 0.0024 17.7 0.9 1.6 2 0 0 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24) DAG1 PF05454.6 KFM13903.1 - 0.0064 15.7 1.5 0.011 14.9 0.2 1.8 1 1 1 2 2 2 1 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF4446 PF14584.1 KFM13903.1 - 0.033 14.0 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) MFS_Mycoplasma PF07672.8 KFM13903.1 - 0.036 13.2 0.1 0.05 12.7 0.1 1.2 1 0 0 1 1 1 0 Mycoplasma MFS transporter Folate_carrier PF01770.13 KFM13903.1 - 0.048 12.1 0.3 0.067 11.6 0.2 1.1 1 0 0 1 1 1 0 Reduced folate carrier OAD_gamma PF04277.8 KFM13903.1 - 2.2 8.6 7.0 9.2 6.7 4.9 2.0 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain MRVI1 PF05781.7 KFM13904.1 - 1e-170 568.7 15.0 1.8e-170 567.9 10.4 1.3 1 0 0 1 1 1 1 MRVI1 protein DUF2799 PF10973.3 KFM13904.1 - 0.2 11.7 4.5 0.12 12.3 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2799) MIF4G PF02854.14 KFM13905.1 - 1.1e-57 194.8 1.6 1.1e-57 194.8 1.1 2.3 2 0 0 2 2 2 1 MIF4G domain W2 PF02020.13 KFM13905.1 - 2.6e-21 75.3 1.3 2.8e-20 72.0 1.0 2.5 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon MA3 PF02847.12 KFM13905.1 - 2.6e-17 62.5 5.7 2.9e-17 62.3 0.1 3.0 3 0 0 3 3 3 1 MA3 domain Glycos_transf_2 PF00535.21 KFM13906.1 - 2.4e-22 79.4 0.1 3.1e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KFM13906.1 - 2.8e-07 30.5 0.1 0.0091 15.8 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 KFM13906.1 - 4.3e-06 26.0 0.0 6e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 KFM13906.1 - 8.1e-06 25.2 0.0 1.9e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Dickkopf_N PF04706.7 KFM13907.1 - 3.8e-18 65.3 20.0 3.8e-18 65.3 13.9 2.9 3 0 0 3 3 3 2 Dickkopf N-terminal cysteine-rich region Prokineticin PF06607.6 KFM13907.1 - 5e-06 26.5 2.9 5e-06 26.5 2.0 2.7 1 1 2 3 3 3 1 Prokineticin CH PF00307.26 KFM13908.1 - 4.6e-19 68.4 0.0 1.3e-18 67.0 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFM13908.1 - 1.2e-12 47.3 0.0 2.8e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 CAMSAP CH domain LIM PF00412.17 KFM13908.1 - 3.9e-09 36.4 10.6 8.8e-09 35.3 7.3 1.7 1 0 0 1 1 1 1 LIM domain FAD_binding_3 PF01494.14 KFM13908.1 - 0.072 12.1 0.2 0.23 10.4 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain DUF3585 PF12130.3 KFM13909.1 - 1e-39 135.6 25.1 1e-39 135.6 17.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3585) LMBR1 PF04791.11 KFM13909.1 - 2.7 6.4 9.0 3.5 6.1 5.6 1.5 1 1 0 1 1 1 0 LMBR1-like membrane protein CH PF00307.26 KFM13910.1 - 1.5e-25 89.2 1.3 2.3e-12 46.8 0.0 2.3 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFM13910.1 - 5.4e-06 25.9 0.0 0.088 12.4 0.0 2.5 2 0 0 2 2 2 2 CAMSAP CH domain FlaG PF03646.10 KFM13910.1 - 0.13 12.4 2.5 0.11 12.7 0.4 1.8 2 0 0 2 2 2 0 FlaG protein SYCE1 PF15233.1 KFM13910.1 - 0.65 9.9 6.0 0.32 10.9 1.7 2.1 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 TEA PF01285.13 KFM13911.1 - 2.5e-179 596.9 0.0 3e-179 596.7 0.0 1.0 1 0 0 1 1 1 1 TEA/ATTS domain family Myb_DNA-binding PF00249.26 KFM13911.1 - 0.084 12.9 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain PAS_11 PF14598.1 KFM13912.1 - 5e-26 90.8 0.2 1.1e-22 80.1 0.1 2.4 2 0 0 2 2 2 2 PAS domain PAS PF00989.19 KFM13912.1 - 2.6e-17 62.6 0.0 8.3e-09 35.2 0.0 2.5 2 0 0 2 2 2 2 PAS fold HLH PF00010.21 KFM13912.1 - 5.7e-17 61.1 0.8 1.1e-16 60.3 0.5 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_3 PF08447.6 KFM13912.1 - 6e-17 61.5 0.0 5e-09 36.1 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.1 KFM13912.1 - 1.5e-07 31.7 0.0 0.0041 17.4 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 KFM13912.1 - 0.00012 22.1 0.0 0.0084 16.1 0.0 2.4 2 0 0 2 2 2 1 PAS fold BTB_2 PF02214.17 KFM13913.1 - 0.00028 21.0 0.0 0.00061 19.9 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Parathyroid PF01279.12 KFM13914.1 - 6.7e-24 84.4 3.4 8e-24 84.1 2.3 1.1 1 0 0 1 1 1 1 Parathyroid hormone family DUF4224 PF13986.1 KFM13914.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) NAD_binding_4 PF07993.7 KFM13915.1 - 4.2e-75 251.8 0.0 5.4e-75 251.5 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.14 KFM13915.1 - 6.1e-23 80.8 1.1 1.4e-22 79.7 0.8 1.7 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KFM13915.1 - 1.9e-09 37.2 0.1 4.4e-09 36.1 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFM13915.1 - 4.4e-06 25.5 0.1 0.0091 14.7 0.1 3.0 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KFM13915.1 - 0.00016 20.7 0.1 0.00043 19.2 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 KFM13915.1 - 0.0016 18.7 0.0 0.0035 17.6 0.0 1.6 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 KFM13915.1 - 0.0034 16.2 0.4 4 6.2 0.2 3.1 2 1 0 2 2 2 2 RmlD substrate binding domain NAD_binding_10 PF13460.1 KFM13915.1 - 0.0045 17.0 0.1 0.091 12.7 0.0 2.8 2 1 0 2 2 2 1 NADH(P)-binding KR PF08659.5 KFM13915.1 - 0.036 13.7 0.0 0.078 12.6 0.0 1.5 1 1 0 1 1 1 0 KR domain DapB_N PF01113.15 KFM13915.1 - 0.097 12.5 0.0 0.42 10.5 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.20 KFM13915.1 - 0.62 9.9 2.3 2.6 7.9 0.2 2.6 2 1 0 2 2 2 0 short chain dehydrogenase Trypsin PF00089.21 KFM13916.1 - 3.3e-140 464.9 0.3 5e-73 245.3 0.0 2.2 2 0 0 2 2 2 2 Trypsin CUB PF00431.15 KFM13916.1 - 2.1e-48 162.9 0.1 1e-24 86.7 0.0 2.4 2 0 0 2 2 2 2 CUB domain DUF1986 PF09342.6 KFM13916.1 - 5.2e-21 75.1 0.1 1.8e-11 43.8 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 KFM13916.1 - 3e-09 36.8 0.0 0.0035 17.3 0.0 2.8 2 1 0 2 2 2 2 Trypsin-like peptidase domain NAD_binding_1 PF00175.16 KFM13917.1 - 6.4e-34 116.8 0.0 1.8e-33 115.3 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KFM13917.1 - 3.5e-31 107.2 0.0 6.5e-31 106.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KFM13917.1 - 1.4e-06 28.2 0.0 2.5e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KFM13917.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain SAM_1 PF00536.25 KFM13918.1 - 2.7e-40 136.3 5.9 2.1e-18 66.2 0.0 4.1 4 0 0 4 4 4 3 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFM13918.1 - 1.5e-39 133.6 3.5 5.6e-15 54.9 0.0 3.9 4 0 0 4 4 4 3 SAM domain (Sterile alpha motif) Integrase_DNA PF02920.10 KFM13918.1 - 1.2e-20 72.7 10.9 2.8e-20 71.5 7.6 1.7 1 0 0 1 1 1 1 DNA binding domain of tn916 integrase Reo_sigmaC PF04582.7 KFM13918.1 - 0.0056 15.9 6.6 0.035 13.3 2.2 2.2 1 1 1 2 2 2 1 Reovirus sigma C capsid protein ADIP PF11559.3 KFM13918.1 - 0.31 10.9 30.5 1.9 8.3 12.9 3.4 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding SAM_PNT PF02198.11 KFM13918.1 - 0.35 10.6 4.0 6.8 6.5 0.0 3.3 3 0 0 3 3 3 0 Sterile alpha motif (SAM)/Pointed domain Occludin_ELL PF07303.8 KFM13918.1 - 0.71 10.6 15.5 0.5 11.1 3.0 3.0 1 1 1 2 2 2 0 Occludin homology domain zf-C4H2 PF10146.4 KFM13918.1 - 0.98 9.3 10.4 2.2 8.2 7.2 1.6 1 0 0 1 1 1 0 Zinc finger-containing protein M_domain PF12938.2 KFM13918.1 - 4.1 7.1 9.6 1.4 8.7 2.9 2.8 3 0 0 3 3 3 0 M domain of GW182 OLF PF02191.11 KFM13919.1 - 6.7e-75 251.5 0.0 8.6e-75 251.2 0.0 1.1 1 0 0 1 1 1 1 Olfactomedin-like domain C2 PF00168.25 KFM13920.1 - 3.4e-57 190.2 0.2 2.2e-28 97.8 0.0 2.4 2 0 0 2 2 2 2 C2 domain PI3K_C2 PF00792.19 KFM13920.1 - 0.0082 15.9 0.0 7 6.4 0.0 3.3 3 0 0 3 3 3 2 Phosphoinositide 3-kinase C2 CEP76-C2 PF15627.1 KFM13920.1 - 0.026 14.0 0.0 3.1 7.2 0.0 2.5 2 0 0 2 2 2 0 CEP76 C2 domain TSP_1 PF00090.14 KFM13921.1 - 1.4e-84 278.0 86.8 3.8e-17 62.1 4.9 6.7 6 0 0 6 6 6 6 Thrombospondin type 1 domain Spond_N PF06468.8 KFM13921.1 - 2.4e-79 265.6 0.2 4.5e-79 264.7 0.2 1.5 1 0 0 1 1 1 1 Spondin_N PTN_MK_C PF01091.13 KFM13921.1 - 5.5 7.0 48.4 0.072 13.0 1.3 6.5 6 0 0 6 6 6 0 PTN/MK heparin-binding protein family, C-terminal domain DUF3827 PF12877.2 KFM13922.1 - 9e-260 863.5 8.2 9e-260 863.5 5.7 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3827) Pkinase PF00069.20 KFM13923.1 - 4.4e-51 173.5 0.0 8.1e-51 172.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM13923.1 - 6.1e-24 84.4 0.0 1.1e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFM13923.1 - 8.9e-06 24.9 0.0 1.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFM13923.1 - 0.0034 17.1 0.0 0.0062 16.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KFM13923.1 - 0.059 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Tcp11 PF05794.8 KFM13924.1 - 2.6e-126 421.8 0.0 3.1e-126 421.6 0.0 1.0 1 0 0 1 1 1 1 T-complex protein 11 DUF1819 PF08849.6 KFM13924.1 - 0.037 13.4 0.2 0.082 12.3 0.2 1.5 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) DEP PF00610.16 KFM13925.1 - 5.1e-16 58.1 1.0 3.5e-15 55.5 0.2 2.5 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Imm16 PF15565.1 KFM13925.1 - 0.019 14.8 0.1 0.16 11.8 0.0 2.4 2 0 0 2 2 2 0 Immunity protein 16 SMC_N PF02463.14 KFM13925.1 - 0.27 10.4 1.8 0.33 10.1 0.3 1.8 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF4211 PF13926.1 KFM13926.1 - 5.7e-35 119.9 0.7 2e-34 118.2 0.5 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) Gla PF00594.15 KFM13927.1 - 3.1e-12 45.9 7.4 7e-12 44.8 5.1 1.5 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain CD34_antigen PF06365.7 KFM13927.1 - 0.00092 18.9 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family Orthoreo_P10 PF07204.6 KFM13927.1 - 0.0018 18.0 0.1 0.0034 17.1 0.1 1.5 1 0 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 EphA2_TM PF14575.1 KFM13927.1 - 0.0021 18.4 0.0 0.0064 16.8 0.0 1.9 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain WBP-1 PF11669.3 KFM13927.1 - 0.0075 16.3 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 WW domain-binding protein 1 IncA PF04156.9 KFM13927.1 - 0.024 14.2 0.1 0.037 13.6 0.1 1.3 1 0 0 1 1 1 0 IncA protein Adeno_E3_CR2 PF02439.10 KFM13927.1 - 0.03 13.8 3.5 0.055 13.0 2.4 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Shisa PF13908.1 KFM13927.1 - 0.062 13.4 0.0 0.075 13.1 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator TMEM190 PF15431.1 KFM13927.1 - 0.086 12.7 0.0 0.27 11.1 0.0 1.7 2 0 0 2 2 2 0 Transmembrane protein 190 TMEM154 PF15102.1 KFM13927.1 - 0.089 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family Rhabdo_glycop PF00974.13 KFM13927.1 - 0.12 10.5 0.0 0.15 10.2 0.0 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Mst1_SARAH PF11629.3 KFM13928.1 - 0.33 10.8 12.5 2.2 8.1 1.1 4.3 3 0 0 3 3 3 0 C terminal SARAH domain of Mst1 PCI PF01399.22 KFM13929.1 - 3.4e-15 56.2 1.5 2.3e-14 53.5 0.6 2.4 2 0 0 2 2 2 1 PCI domain Death PF00531.17 KFM13929.1 - 0.075 12.8 1.2 1.3 8.8 0.0 2.8 2 0 0 2 2 2 0 Death domain EF-hand_7 PF13499.1 KFM13930.1 - 2.1e-20 72.6 17.1 9e-10 38.5 0.1 3.3 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 KFM13930.1 - 1e-18 65.1 14.2 0.0014 17.7 0.0 6.7 6 0 0 6 6 6 6 EF hand EF-hand_6 PF13405.1 KFM13930.1 - 1.3e-16 58.8 13.9 0.0019 17.9 0.0 6.5 6 0 0 6 6 6 6 EF-hand domain EF-hand_5 PF13202.1 KFM13930.1 - 9.6e-10 37.3 25.3 0.0073 15.6 0.7 6.7 7 0 0 7 7 7 4 EF hand EF-hand_8 PF13833.1 KFM13930.1 - 1.5e-07 30.9 14.5 0.017 14.7 0.4 6.2 6 1 0 6 6 6 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFM13930.1 - 0.00031 20.7 9.7 0.032 14.2 0.1 3.6 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_like PF09279.6 KFM13930.1 - 0.023 14.7 0.8 0.41 10.6 0.0 3.0 3 1 0 3 3 3 0 Phosphoinositide-specific phospholipase C, efhand-like DUF3887 PF13026.1 KFM13930.1 - 0.58 10.4 6.5 0.3 11.4 0.7 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3887) DUF2852 PF11014.3 KFM13930.1 - 1.4 8.9 7.0 4.9 7.1 2.8 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2852) EF-hand_4 PF12763.2 KFM13930.1 - 6.9 6.4 13.2 2.2 8.0 0.1 4.3 4 1 1 5 5 5 0 Cytoskeletal-regulatory complex EF hand PAX PF00292.13 KFM13931.1 - 2.7e-38 130.5 0.1 5.8e-38 129.4 0.1 1.5 1 0 0 1 1 1 1 'Paired box' domain Homeobox PF00046.24 KFM13931.1 - 3.1e-23 81.1 4.5 5.5e-23 80.3 3.1 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFM13931.1 - 0.085 12.5 1.1 0.14 11.8 0.1 1.9 2 0 0 2 2 2 0 Homeobox KN domain PAXNEB PF05625.6 KFM13932.1 - 5e-89 298.6 0.0 5.5e-89 298.5 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein Peptidase_S24 PF00717.18 KFM13933.1 - 5.9e-14 51.4 0.0 1e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 KFM13933.1 - 2.1e-07 30.5 0.0 0.00032 20.2 0.0 2.7 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 DnaJ PF00226.26 KFM13934.1 - 1e-19 70.0 0.8 1.4e-19 69.5 0.5 1.2 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.8 KFM13934.1 - 6.5e-12 44.7 5.9 1.1e-11 44.1 4.1 1.4 1 0 0 1 1 1 1 CSL zinc finger fn1 PF00039.13 KFM13934.1 - 0.027 14.2 1.5 0.077 12.8 1.0 1.7 1 0 0 1 1 1 0 Fibronectin type I domain ubiquitin PF00240.18 KFM13934.1 - 0.038 13.3 0.5 0.78 9.1 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin family DUF3728 PF12528.3 KFM13935.1 - 0.31 11.4 1.7 0.72 10.2 0.2 2.1 1 1 1 2 2 2 0 Prepilin peptidase dependent protein C (DUF3728) Metallophos PF00149.23 KFM13937.1 - 2.3e-09 36.9 2.3 5e-09 35.8 1.6 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KFM13937.1 - 9.9e-06 25.4 0.0 1.9e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ARF7EP_C PF14949.1 KFM13938.1 - 1.6e-36 124.8 6.0 1.6e-36 124.8 4.2 1.7 2 0 0 2 2 2 1 ARF7 effector protein C-terminus Cys_knot PF00007.17 KFM13939.1 - 1.6e-30 105.2 17.2 2e-30 104.9 11.9 1.1 1 0 0 1 1 1 1 Cystine-knot domain K_channel_TID PF07941.6 KFM13940.1 - 3.8e-34 116.7 17.0 7.8e-34 115.7 11.8 1.6 1 0 0 1 1 1 1 Potassium channel Kv1.4 tandem inactivation domain Ion_trans PF00520.26 KFM13940.1 - 5.2e-34 117.2 5.5 5.2e-34 117.2 3.8 1.9 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 KFM13940.1 - 1.4e-27 95.7 0.1 3.1e-27 94.5 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.11 KFM13940.1 - 1.9e-13 49.9 7.0 2.8e-13 49.3 3.5 2.2 2 0 0 2 2 2 1 Ion channel PKD_channel PF08016.7 KFM13940.1 - 0.001 17.5 0.4 0.001 17.5 0.3 1.6 1 1 1 2 2 2 1 Polycystin cation channel Methyltransf_5 PF01795.14 KFM13941.1 - 8.8e-81 271.5 0.1 1.6e-79 267.3 0.1 1.9 1 1 0 1 1 1 1 MraW methylase family Methyltransf_26 PF13659.1 KFM13941.1 - 4.9e-05 23.3 0.0 0.00022 21.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFM13941.1 - 7.8e-05 23.2 0.0 0.0047 17.4 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFM13941.1 - 0.0005 19.6 0.0 0.92 9.0 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 KFM13941.1 - 0.018 15.4 0.1 0.89 10.0 0.0 2.8 3 0 0 3 3 3 0 Methyltransferase domain Adenine_glyco PF03352.8 KFM13941.1 - 0.021 14.3 0.2 0.2 11.1 0.0 2.0 2 0 0 2 2 2 0 Methyladenine glycosylase MTS PF05175.9 KFM13941.1 - 0.025 13.9 0.0 3.3 7.0 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_15 PF09445.5 KFM13941.1 - 0.041 13.4 0.0 0.066 12.7 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase DUF615 PF04751.9 KFM13941.1 - 0.1 12.2 0.6 5.6 6.5 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF615) Kinesin PF00225.18 KFM13942.1 - 1.1e-113 379.3 1.0 1.1e-113 379.3 0.7 2.6 2 1 1 3 3 3 1 Kinesin motor domain DUF2443 PF10398.4 KFM13942.1 - 4.4 7.1 7.2 0.78 9.5 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2443) NGF PF00243.13 KFM13943.1 - 5.2e-59 197.0 3.5 7.2e-59 196.6 2.4 1.2 1 0 0 1 1 1 1 Nerve growth factor family PDZ PF00595.19 KFM13944.1 - 2.9e-21 75.4 0.6 4.3e-21 74.8 0.4 1.2 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) L27 PF02828.11 KFM13944.1 - 1.2e-20 72.8 0.2 2.3e-20 72.0 0.1 1.5 1 0 0 1 1 1 1 L27 domain PDZ_2 PF13180.1 KFM13944.1 - 0.00057 19.7 0.0 0.0009 19.0 0.0 1.3 1 0 0 1 1 1 1 PDZ domain DUF2057 PF09829.4 KFM13944.1 - 0.0039 16.8 0.5 0.0097 15.5 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2057) LRR_8 PF13855.1 KFM13945.1 - 1.9e-98 322.2 88.2 2.2e-16 59.3 1.4 8.8 1 1 11 12 12 12 12 Leucine rich repeat LRR_4 PF12799.2 KFM13945.1 - 3.5e-47 157.3 46.2 2.2e-10 39.9 0.2 10.8 4 4 5 10 10 10 10 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFM13945.1 - 3.6e-43 146.3 0.0 1.2e-12 47.6 0.0 4.4 1 1 4 5 5 5 5 Leucine rich repeats (6 copies) LRR_1 PF00560.28 KFM13945.1 - 1.1e-39 128.3 34.3 0.0049 16.7 0.1 16.0 16 0 0 16 16 16 14 Leucine Rich Repeat LRR_7 PF13504.1 KFM13945.1 - 2.1e-19 66.1 31.1 0.77 10.2 0.1 15.6 17 0 0 17 17 17 4 Leucine rich repeat 7tm_1 PF00001.16 KFM13945.1 - 2e-15 56.6 12.3 3.2e-15 55.9 8.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_9 PF14580.1 KFM13945.1 - 8.3e-12 45.0 6.6 0.0017 17.9 0.1 4.7 1 1 4 5 5 5 3 Leucine-rich repeat LRR_6 PF13516.1 KFM13945.1 - 9.2e-12 43.7 42.1 0.43 10.7 0.0 14.5 13 2 2 15 15 15 6 Leucine Rich repeat Sigma70_r4 PF04545.11 KFM13945.1 - 0.029 13.6 0.1 0.073 12.3 0.1 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 DUF4207 PF13904.1 KFM13946.1 - 1.8e-28 99.6 36.0 2.2e-28 99.3 25.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4207) SAPS PF04499.10 KFM13946.1 - 0.0088 14.7 5.2 0.0086 14.7 3.6 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein DUF3824 PF12868.2 KFM13946.1 - 0.019 15.8 7.4 0.019 15.8 5.1 2.5 1 1 1 2 2 2 0 Domain of unknwon function (DUF3824) DUF572 PF04502.8 KFM13946.1 - 0.57 9.3 25.5 0.72 9.0 17.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Bunya_RdRp PF04196.7 KFM13946.1 - 3.8 5.3 9.7 4.4 5.1 6.7 1.0 1 0 0 1 1 1 0 Bunyavirus RNA dependent RNA polymerase Borrelia_P83 PF05262.6 KFM13946.1 - 3.9 5.6 32.5 4.3 5.4 22.5 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein BAF PF02961.9 KFM13946.1 - 7.3 6.9 8.4 4.1 7.7 1.2 2.7 2 1 1 3 3 3 0 Barrier to autointegration factor SSF PF00474.12 KFM13948.1 - 3.5e-39 134.6 21.3 4.5e-39 134.2 14.8 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family NdhL PF10716.4 KFM13948.1 - 0.037 13.8 2.5 0.18 11.5 1.0 2.6 2 0 0 2 2 2 0 NADH dehydrogenase transmembrane subunit Anoctamin PF04547.7 KFM13949.1 - 3.1e-157 523.8 14.2 3.8e-157 523.5 9.8 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Leu_zip PF15294.1 KFM13950.1 - 5.2e-64 216.0 32.6 6.2e-64 215.7 22.6 1.0 1 0 0 1 1 1 1 Leucine zipper Reo_sigmaC PF04582.7 KFM13950.1 - 0.0043 16.2 3.6 0.0043 16.2 2.5 2.0 1 1 0 2 2 2 1 Reovirus sigma C capsid protein DUF4107 PF13389.1 KFM13950.1 - 0.0092 15.6 0.1 0.014 15.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) DUF2119 PF09892.4 KFM13950.1 - 0.051 12.8 2.1 0.87 8.8 0.6 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2119) Fib_alpha PF08702.5 KFM13950.1 - 0.12 12.4 22.7 1.2 9.2 3.3 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1612 PF07756.7 KFM13950.1 - 0.3 11.1 8.1 9 6.4 0.2 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1612) CTNNB1_binding PF08347.6 KFM13950.1 - 0.35 11.0 6.0 0.36 11.0 3.7 1.4 1 1 0 1 1 1 0 N-terminal CTNNB1 binding LAGLIDADG_1 PF00961.14 KFM13950.1 - 0.59 10.7 4.1 1.1 9.8 2.7 1.6 1 1 0 1 1 1 0 LAGLIDADG endonuclease DUF3584 PF12128.3 KFM13950.1 - 0.69 7.1 28.0 1 6.6 19.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FTCD_C PF04961.7 KFM13950.1 - 1 8.7 9.2 0.15 11.4 2.9 2.2 1 1 1 2 2 2 0 Formiminotransferase-cyclodeaminase EzrA PF06160.7 KFM13950.1 - 1.1 7.3 26.9 2.7 6.0 18.6 2.0 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA GvpL_GvpF PF06386.6 KFM13950.1 - 1.2 8.6 13.6 3.8 7.0 7.4 2.2 1 1 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Spc7 PF08317.6 KFM13950.1 - 2 7.0 33.2 11 4.5 22.1 2.0 1 1 0 1 1 1 0 Spc7 kinetochore protein SSFA2_C PF14723.1 KFM13950.1 - 3.1 7.4 13.6 0.95 9.1 5.6 2.2 1 1 1 2 2 2 0 Sperm-specific antigen 2 C-terminus Filament PF00038.16 KFM13950.1 - 4.2 6.7 30.0 1.2e+03 -1.4 20.9 2.6 1 1 0 1 1 1 0 Intermediate filament protein IncA PF04156.9 KFM13950.1 - 4.3 6.8 39.8 4.4 6.8 16.4 2.8 1 1 1 2 2 2 0 IncA protein UPF0242 PF06785.6 KFM13950.1 - 6.1 5.4 27.0 4 6.0 9.1 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) TMEM192 PF14802.1 KFM13950.1 - 7.8 5.2 7.9 58 2.4 5.4 2.1 1 1 0 1 1 1 0 TMEM192 family Sprouty PF05210.8 KFM13951.1 - 4.2e-32 110.3 28.4 6.5e-32 109.7 19.7 1.3 1 0 0 1 1 1 1 Sprouty protein (Spry) Sec23_trunk PF04811.10 KFM13952.1 - 8e-85 284.0 0.1 1.2e-84 283.4 0.1 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KFM13952.1 - 2e-24 84.9 0.3 3.7e-24 84.1 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KFM13952.1 - 9.1e-18 64.5 0.1 2.3e-17 63.2 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KFM13952.1 - 1.1e-14 53.6 8.7 2.4e-14 52.5 6.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KFM13952.1 - 2e-07 30.6 0.0 4.8e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat MT-A70 PF05063.9 KFM13953.1 - 4.9e-63 211.8 0.0 6.9e-63 211.3 0.0 1.2 1 0 0 1 1 1 1 MT-A70 SRCR PF00530.13 KFM13954.1 - 2.8e-120 393.2 35.1 1.8e-33 114.7 4.5 4.0 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 KFM13954.1 - 1.5e-22 79.7 19.2 7.3e-06 26.1 1.4 4.8 4 2 0 4 4 4 4 Scavenger receptor cysteine-rich domain HMG_CoA_synt_N PF01154.12 KFM13954.1 - 0.038 13.5 1.8 0.24 10.9 0.0 2.5 3 0 0 3 3 3 0 Hydroxymethylglutaryl-coenzyme A synthase N terminal SapB_2 PF03489.12 KFM13954.1 - 0.073 13.1 0.1 1e+02 3.0 0.0 4.1 4 0 0 4 4 4 0 Saposin-like type B, region 2 HSNSD PF12062.3 KFM13955.1 - 3.7e-259 860.0 0.4 5e-259 859.6 0.3 1.1 1 0 0 1 1 1 1 heparan sulfate-N-deacetylase Sulfotransfer_1 PF00685.22 KFM13955.1 - 4.4e-39 134.3 0.0 7.4e-39 133.6 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Kelch_1 PF01344.20 KFM13957.1 - 4.9e-32 109.2 0.0 5.1e-09 35.5 0.0 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 KFM13957.1 - 2.7e-27 93.7 0.4 9.4e-07 28.7 0.0 5.9 6 1 1 7 7 7 4 Kelch motif BTB PF00651.26 KFM13957.1 - 1.5e-13 50.6 0.0 2.5e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.10 KFM13957.1 - 2.4e-12 46.0 0.0 0.052 13.3 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.1 KFM13957.1 - 1.9e-09 37.4 0.2 0.39 10.9 0.0 4.9 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_4 PF13418.1 KFM13957.1 - 5.8e-09 35.5 0.7 0.11 12.3 0.0 5.7 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.1 KFM13957.1 - 0.016 15.1 0.1 18 5.4 0.1 3.6 3 0 0 3 3 3 0 Kelch motif RhoGEF PF00621.15 KFM13958.1 - 5.3e-41 140.4 0.7 5.3e-41 140.4 0.5 1.9 2 0 0 2 2 2 1 RhoGEF domain BBS2_Mid PF14783.1 KFM13958.1 - 0.034 13.9 0.1 0.27 11.0 0.0 2.3 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region DUF3467 PF11950.3 KFM13958.1 - 0.047 13.6 0.0 4.3 7.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3467) GKAP PF03359.8 KFM13959.1 - 7.3e-149 496.2 4.3 7.3e-149 496.2 3.0 2.6 3 0 0 3 3 3 1 Guanylate-kinase-associated protein (GKAP) protein F-box PF00646.28 KFM13964.1 - 0.0025 17.4 0.1 0.012 15.2 0.0 2.2 2 0 0 2 2 2 1 F-box domain Elongin_A PF06881.6 KFM13964.1 - 0.0044 17.3 2.1 0.0066 16.8 0.1 2.2 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box-like PF12937.2 KFM13964.1 - 0.079 12.7 0.1 0.21 11.3 0.1 1.8 1 0 0 1 1 1 0 F-box-like HSCB_C PF07743.8 KFM13964.1 - 0.1 13.0 0.0 0.27 11.7 0.0 1.7 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain FAM110_C PF14160.1 KFM13965.1 - 7.6e-38 129.8 1.3 7.6e-38 129.8 0.9 2.3 2 0 0 2 2 2 1 Centrosome-associated C terminus FAM110_N PF14161.1 KFM13965.1 - 1.3e-23 83.3 0.9 9.7e-23 80.5 0.1 2.3 2 0 0 2 2 2 1 Centrosome-associated N terminus Trypsin PF00089.21 KFM13966.1 - 7e-48 163.0 0.0 7.8e-48 162.9 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 KFM13966.1 - 4.2e-06 26.2 0.0 5.4e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 KFM13966.1 - 0.088 12.7 0.0 0.15 12.0 0.0 1.4 1 1 0 1 1 1 0 Trypsin-like peptidase domain DCX PF03607.12 KFM13968.1 - 6.3e-32 108.9 0.0 2.3e-21 75.1 0.0 2.2 2 0 0 2 2 2 2 Doublecortin Sox_C_TAD PF12067.3 KFM13969.1 - 1e-53 182.4 10.0 1.5e-53 181.9 6.9 1.2 1 0 0 1 1 1 1 Sox C-terminal transactivation domain HMG_box PF00505.14 KFM13969.1 - 2.4e-08 34.0 0.1 4e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFM13969.1 - 0.0021 18.3 0.1 0.004 17.4 0.1 1.4 1 0 0 1 1 1 1 HMG-box domain G-patch PF01585.18 KFM13971.1 - 2.2e-16 59.3 4.3 2.2e-16 59.3 3.0 1.9 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 KFM13971.1 - 5.1e-09 35.8 1.4 5.1e-09 35.8 1.0 2.2 3 0 0 3 3 3 1 DExH-box splicing factor binding site XK-related PF09815.4 KFM13972.1 - 2e-105 352.4 19.6 2.4e-105 352.2 13.6 1.1 1 0 0 1 1 1 1 XK-related protein Meleagrin PF08189.6 KFM13973.1 - 7.1e-24 83.0 13.5 8.6e-24 82.7 9.3 1.1 1 0 0 1 1 1 1 Meleagrin/Cygnin family DIM PF08194.7 KFM13973.1 - 0.048 13.6 0.8 0.048 13.6 0.6 1.7 2 0 0 2 2 2 0 DIM protein zf-MYND PF01753.13 KFM13973.1 - 0.62 9.9 7.8 0.43 10.4 4.3 1.6 1 1 0 1 1 1 0 MYND finger Nodulin_late PF07127.6 KFM13973.1 - 4.3 7.5 7.6 60 3.8 5.5 2.1 1 1 1 2 2 2 0 Late nodulin protein Meleagrin PF08189.6 KFM13974.1 - 7.1e-24 83.0 13.5 8.6e-24 82.7 9.3 1.1 1 0 0 1 1 1 1 Meleagrin/Cygnin family zf-MYND PF01753.13 KFM13974.1 - 0.62 9.9 7.8 0.43 10.4 4.3 1.6 1 1 0 1 1 1 0 MYND finger Myotub-related PF06602.9 KFM13975.1 - 2.5e-99 332.4 0.5 2.9e-99 332.1 0.3 1.0 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Hydrolase_6 PF13344.1 KFM13975.1 - 0.035 13.9 0.0 0.068 13.0 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Epimerase PF01370.16 KFM13976.1 - 1.5e-20 73.6 0.0 1e-19 70.9 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KFM13976.1 - 2.1e-08 33.4 0.0 5.2e-08 32.1 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 KFM13976.1 - 7.1e-08 31.6 0.0 9.9e-08 31.1 0.0 1.3 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 KFM13976.1 - 6e-07 28.4 0.0 9.6e-07 27.7 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KFM13976.1 - 0.00069 18.5 0.0 0.01 14.7 0.1 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KFM13976.1 - 0.0037 17.2 0.1 0.0084 16.0 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KFM13976.1 - 0.022 14.4 0.1 0.078 12.6 0.0 1.8 2 0 0 2 2 2 0 KR domain DUF1100 PF06500.6 KFM13976.1 - 0.031 12.8 0.0 0.13 10.8 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1100) DUF3259 PF11652.3 KFM13977.1 - 6.1e-48 160.9 2.6 1e-47 160.1 1.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3259) LURAP PF14854.1 KFM13977.1 - 0.0014 18.3 0.2 0.0025 17.5 0.1 1.5 1 0 0 1 1 1 1 Leucine rich adaptor protein DUF2388 PF09498.5 KFM13977.1 - 0.031 13.9 0.1 0.059 13.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2388) Dapper PF15268.1 KFM13977.1 - 0.18 10.5 4.8 0.093 11.5 2.1 1.4 1 1 0 1 1 1 0 Dapper IncA PF04156.9 KFM13977.1 - 0.39 10.2 8.4 0.039 13.5 0.9 2.0 1 1 1 2 2 2 0 IncA protein DUF4530 PF15039.1 KFM13977.1 - 2.7 7.9 9.8 0.041 13.7 0.8 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4530) Pkinase_Tyr PF07714.12 KFM13978.1 - 1.2e-94 316.1 0.0 1.6e-94 315.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM13978.1 - 1.1e-48 165.6 0.0 1.6e-48 165.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 KFM13978.1 - 4e-27 93.8 0.1 7.4e-27 92.9 0.1 1.5 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.23 KFM13978.1 - 1.8e-14 52.8 0.0 4e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFM13978.1 - 4.2e-11 42.2 0.0 9.3e-11 41.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFM13978.1 - 3.9e-08 32.6 0.0 1e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 KFM13978.1 - 0.0083 16.3 0.2 0.027 14.6 0.0 1.9 2 0 0 2 2 2 1 Bacterial SH3 domain SusD-like_3 PF14322.1 KFM13978.1 - 0.0097 15.9 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 Starch-binding associating with outer membrane GATA-N PF05349.7 KFM13979.1 - 3.3e-65 219.6 25.4 4.5e-65 219.1 17.6 1.2 1 0 0 1 1 1 1 GATA-type transcription activator, N-terminal GATA PF00320.22 KFM13979.1 - 1e-31 107.9 15.5 2.2e-16 58.8 2.9 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 KFM13979.1 - 9.7e-06 24.8 8.5 0.0071 15.6 0.4 2.9 3 0 0 3 3 3 2 TFIIB zinc-binding ArfGap PF01412.13 KFM13979.1 - 0.0045 16.7 1.9 0.13 12.0 0.1 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Zn-ribbon_8 PF09723.5 KFM13979.1 - 0.0047 16.8 2.4 0.3 11.0 0.2 3.2 3 0 0 3 3 3 1 Zinc ribbon domain OrfB_Zn_ribbon PF07282.6 KFM13979.1 - 0.019 14.6 4.2 0.38 10.4 0.1 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DZR PF12773.2 KFM13979.1 - 0.022 14.5 6.1 1.9 8.3 4.6 2.6 1 1 1 2 2 2 0 Double zinc ribbon eIF-5_eIF-2B PF01873.12 KFM13979.1 - 0.031 13.9 3.3 3.6 7.2 0.4 2.2 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Elf1 PF05129.8 KFM13979.1 - 0.041 13.5 1.6 4.3 7.0 0.0 2.5 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like BaffR-Tall_bind PF09256.5 KFM13979.1 - 0.09 12.3 3.1 2 8.0 0.0 3.2 3 0 0 3 3 3 0 BAFF-R, TALL-1 binding Cytochrome_C7 PF14522.1 KFM13979.1 - 0.18 11.4 6.1 0.21 11.2 2.1 2.2 1 1 1 2 2 2 0 Cytochrome c7 Prim_Zn_Ribbon PF08273.7 KFM13979.1 - 0.2 11.7 9.6 0.24 11.4 2.1 2.6 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase DUF2387 PF09526.5 KFM13979.1 - 0.28 11.1 4.7 10 6.0 0.1 3.0 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) Zn_Tnp_IS1595 PF12760.2 KFM13979.1 - 0.3 10.9 11.0 0.09 12.6 0.7 2.7 2 1 1 3 3 3 0 Transposase zinc-ribbon domain Cytochrome_C554 PF13435.1 KFM13979.1 - 0.43 10.6 3.1 1.6 8.7 2.1 2.0 1 1 0 1 1 1 0 Cytochrome c554 and c-prime Cytochrom_c3_2 PF14537.1 KFM13979.1 - 1.5 9.2 5.3 0.62 10.4 0.5 2.1 1 1 1 2 2 2 0 Cytochrome c3 C1_3 PF07649.7 KFM13979.1 - 3.2 7.8 6.6 22 5.1 0.1 3.3 3 0 0 3 3 3 0 C1-like domain H2TH PF06831.9 KFM13980.1 - 4e-13 48.9 0.0 6.7e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.19 KFM13980.1 - 7.5e-09 35.9 0.0 1.7e-08 34.8 0.0 1.6 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase N-terminal domain SQS_PSY PF00494.14 KFM13981.1 - 1.4e-36 126.1 0.0 2e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase HAUS4 PF14735.1 KFM13981.1 - 0.073 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 Peptidase_C1 PF00112.18 KFM13982.1 - 7.4e-67 225.4 2.5 8.9e-67 225.1 1.8 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.8 KFM13982.1 - 5.7e-19 67.4 0.1 1e-18 66.6 0.1 1.4 1 0 0 1 1 1 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.10 KFM13982.1 - 0.12 10.8 1.4 3.8 5.9 0.2 2.1 2 0 0 2 2 2 0 Peptidase C1-like family Defensin_beta PF00711.14 KFM13983.1 - 4.4e-10 39.3 13.0 5.1e-10 39.0 9.0 1.1 1 0 0 1 1 1 1 Beta defensin Defensin_big PF14862.1 KFM13983.1 - 1.8e-05 24.6 2.1 1.9e-05 24.6 1.5 1.1 1 0 0 1 1 1 1 Big defensin Defensin_beta_2 PF13841.1 KFM13983.1 - 0.29 11.5 13.1 0.45 10.9 9.1 1.3 1 1 0 1 1 1 0 Beta defensin Gamma-thionin PF00304.15 KFM13983.1 - 0.33 10.9 11.3 0.42 10.6 7.8 1.1 1 0 0 1 1 1 0 Gamma-thionin family Defensin_beta_2 PF13841.1 KFM13984.1 - 0.00029 21.1 7.5 0.00036 20.7 5.2 1.1 1 0 0 1 1 1 1 Beta defensin Defensin_beta PF00711.14 KFM13984.1 - 0.00094 19.0 6.5 0.0012 18.7 4.5 1.1 1 0 0 1 1 1 1 Beta defensin Defensin_beta PF00711.14 KFM13985.1 - 1.6e-05 24.7 25.1 2.8e-05 23.9 6.1 2.8 2 1 0 2 2 2 2 Beta defensin Inhibitor_I68 PF10468.4 KFM13985.1 - 0.023 14.8 10.8 0.031 14.4 7.5 1.2 1 0 0 1 1 1 0 Carboxypeptidase inhibitor I68 DIM PF08194.7 KFM13985.1 - 0.17 11.8 2.3 0.31 11.0 1.6 1.4 1 0 0 1 1 1 0 DIM protein Defensin_beta PF00711.14 KFM13986.1 - 8.3e-10 38.4 7.2 9.6e-10 38.2 5.0 1.1 1 0 0 1 1 1 1 Beta defensin Defensin_propep PF00879.13 KFM13986.1 - 0.015 15.2 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Defensin propeptide Defensin_beta PF00711.14 KFM13987.1 - 2.3e-11 43.4 6.0 2.5e-11 43.3 4.2 1.0 1 0 0 1 1 1 1 Beta defensin Defensin_big PF14862.1 KFM13987.1 - 0.32 11.1 3.0 0.34 10.9 2.1 1.1 1 0 0 1 1 1 0 Big defensin Defensin_beta PF00711.14 KFM13988.1 - 9.9e-09 34.9 10.5 1.2e-08 34.7 7.3 1.1 1 0 0 1 1 1 1 Beta defensin Toxin_12 PF07740.7 KFM13988.1 - 9.6 6.7 7.1 10 6.7 0.3 2.2 2 0 0 2 2 2 0 Ion channel inhibitory toxin Defensin_beta PF00711.14 KFM13989.1 - 2.3e-08 33.8 10.9 2.7e-08 33.6 7.6 1.1 1 0 0 1 1 1 1 Beta defensin DUF2733 PF10813.3 KFM13989.1 - 0.97 9.0 3.5 17 5.0 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2733) Defensin_beta PF00711.14 KFM13990.1 - 4.3e-07 29.7 11.9 5.2e-07 29.4 8.2 1.1 1 0 0 1 1 1 1 Beta defensin Defensin_propep PF00879.13 KFM13990.1 - 0.021 14.7 0.1 0.024 14.5 0.0 1.1 1 0 0 1 1 1 0 Defensin propeptide Defensin_beta PF00711.14 KFM13991.1 - 2.1e-08 33.9 11.1 2.7e-08 33.5 7.7 1.2 1 0 0 1 1 1 1 Beta defensin Defensin_propep PF00879.13 KFM13991.1 - 0.0067 16.3 3.1 0.0079 16.1 2.1 1.1 1 0 0 1 1 1 1 Defensin propeptide DAGK_cat PF00781.19 KFM13992.1 - 0.084 12.3 1.8 5.5 6.4 0.6 2.3 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain TRAM1 PF08390.6 KFM13993.1 - 4e-21 74.2 0.5 4e-21 74.2 0.4 2.0 2 0 0 2 2 2 1 TRAM1-like protein TRAM_LAG1_CLN8 PF03798.11 KFM13993.1 - 8.8e-19 67.8 17.2 1.6e-18 67.0 11.9 1.4 1 0 0 1 1 1 1 TLC domain RhodobacterPufX PF11511.3 KFM13993.1 - 0.053 12.9 0.8 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 Intrinsic membrane protein PufX DUF1126 PF06565.7 KFM13994.1 - 9e-46 153.0 1.4 3e-14 52.1 0.1 3.9 4 0 0 4 4 4 3 Repeat of unknown function (DUF1126) EF-hand_1 PF00036.27 KFM13994.1 - 0.0042 16.2 0.8 0.019 14.2 0.0 2.6 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 KFM13994.1 - 0.0069 16.1 0.3 0.031 14.1 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 KFM13994.1 - 0.022 14.9 0.3 0.11 12.6 0.0 2.4 2 1 0 2 2 2 0 EF-hand domain pair HlyIII PF03006.15 KFM13995.1 - 1.9e-45 154.9 17.2 1.9e-45 154.9 11.9 1.3 2 0 0 2 2 2 1 Haemolysin-III related MCM PF00493.18 KFM13997.1 - 1.4e-126 421.8 0.1 2e-126 421.2 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KFM13997.1 - 3.6e-14 53.2 0.0 1.3e-13 51.5 0.0 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KFM13997.1 - 7.2e-07 28.5 0.0 4.7e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KFM13997.1 - 0.012 15.2 0.0 0.035 13.7 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFM13997.1 - 0.038 13.7 0.0 0.13 12.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 KFM13997.1 - 0.083 12.3 0.0 0.25 10.8 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain IL17 PF06083.6 KFM13998.1 - 7.9e-29 99.5 0.1 1.2e-28 98.9 0.1 1.2 1 0 0 1 1 1 1 Interleukin-17 Adeno_E3A PF05248.7 KFM13998.1 - 0.058 13.4 0.9 0.087 12.8 0.6 1.3 1 0 0 1 1 1 0 Adenovirus E3A IL17 PF06083.6 KFM13999.1 - 1.3e-29 102.0 0.7 2.3e-29 101.2 0.5 1.4 1 0 0 1 1 1 1 Interleukin-17 TF_AP-2 PF03299.9 KFM14002.1 - 4.5e-92 307.3 0.0 6.5e-92 306.7 0.0 1.2 1 0 0 1 1 1 1 Transcription factor AP-2 CAP PF00188.21 KFM14003.1 - 1.2e-21 77.4 5.1 1.7e-21 76.9 3.6 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Crisp PF08562.5 KFM14003.1 - 1.4e-21 76.4 17.7 1.4e-21 76.4 12.3 2.1 2 0 0 2 2 2 1 Crisp Ammonium_transp PF00909.16 KFM14004.1 - 1.4e-80 270.7 21.6 1.8e-80 270.3 15.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family p450 PF00067.17 KFM14005.1 - 9.5e-137 456.2 0.1 1.1e-136 456.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KFM14006.1 - 2.7e-136 454.7 0.1 3.1e-136 454.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 CENP-Q PF13094.1 KFM14007.1 - 2.4e-20 73.1 14.2 2.4e-20 73.1 9.8 1.4 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit V_ATPase_I PF01496.14 KFM14007.1 - 0.00098 17.1 8.7 0.0011 16.8 6.1 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF812 PF05667.6 KFM14007.1 - 0.0018 16.8 10.7 0.0038 15.7 7.4 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF812) DUF4460 PF14687.1 KFM14007.1 - 0.042 13.6 1.8 0.11 12.2 1.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) Tropomyosin_1 PF12718.2 KFM14007.1 - 0.058 13.2 13.8 0.019 14.8 7.6 1.7 2 0 0 2 2 2 0 Tropomyosin like Interfer-bind PF09294.5 KFM14007.1 - 0.086 12.8 1.1 0.15 12.0 0.2 1.8 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III Spc7 PF08317.6 KFM14007.1 - 0.091 11.4 15.3 0.0092 14.6 7.6 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF2051 PF09738.4 KFM14007.1 - 0.17 11.1 11.9 0.1 11.8 7.2 1.6 1 1 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) STAG PF08514.6 KFM14007.1 - 0.24 11.1 3.7 0.17 11.6 1.2 1.7 1 1 0 1 1 1 0 STAG domain Tropomyosin PF00261.15 KFM14007.1 - 0.26 10.3 17.6 0.061 12.3 8.5 2.1 1 1 0 1 1 1 0 Tropomyosin Nsp1_C PF05064.8 KFM14007.1 - 0.52 9.9 14.2 0.26 10.9 5.4 2.5 2 0 0 2 2 2 0 Nsp1-like C-terminal region ATG16 PF08614.6 KFM14007.1 - 0.56 9.9 16.7 0.03 14.1 7.6 1.8 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Syntaxin-6_N PF09177.6 KFM14007.1 - 0.66 10.4 9.8 2.9 8.3 3.3 3.0 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Hormone_1 PF00103.15 KFM14007.1 - 0.73 9.1 7.1 0.24 10.6 1.6 2.3 2 1 1 3 3 3 0 Somatotropin hormone family DUF3763 PF12592.3 KFM14007.1 - 0.82 9.3 7.2 8.6 6.0 0.7 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3763) DUF4140 PF13600.1 KFM14007.1 - 1.2 9.6 7.7 0.78 10.2 2.7 2.4 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Bacillus_HBL PF05791.6 KFM14007.1 - 1.4 8.2 12.9 0.79 9.0 5.2 2.5 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) PNK3P PF08645.6 KFM14007.1 - 1.8 7.9 6.6 10 5.5 0.8 2.9 2 1 1 3 3 3 0 Polynucleotide kinase 3 phosphatase Spc24 PF08286.6 KFM14007.1 - 2.7 7.7 12.6 1.1 8.9 6.0 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 ERM PF00769.14 KFM14007.1 - 3.2 7.2 18.3 0.48 9.9 9.7 1.9 2 1 0 2 2 2 0 Ezrin/radixin/moesin family Atg14 PF10186.4 KFM14007.1 - 6 5.7 14.6 14 4.4 8.2 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Laminin_II PF06009.7 KFM14007.1 - 9.4 5.9 11.5 0.74 9.5 3.8 2.2 2 1 0 2 2 2 0 Laminin Domain II MM_CoA_mutase PF01642.17 KFM14008.1 - 4.4e-252 836.7 0.0 5.2e-252 836.5 0.0 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.14 KFM14008.1 - 1.2e-13 50.9 0.4 3.7e-13 49.3 0.1 2.0 2 0 0 2 2 2 1 B12 binding domain PMBR PF09373.5 KFM14008.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Pseudomurein-binding repeat 7tm_1 PF00001.16 KFM14009.1 - 3.9e-39 134.3 14.8 4.7e-39 134.0 10.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 KFM14009.1 - 2.5e-06 26.8 12.2 4.1e-06 26.1 8.5 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv ChlI PF13541.1 KFM14009.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Subunit ChlI of Mg-chelatase DUF1230 PF06799.6 KFM14009.1 - 0.52 10.1 5.9 0.98 9.2 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1230) Ni_hydr_CYTB PF01292.15 KFM14009.1 - 1.5 8.1 8.2 1.2 8.5 4.1 1.9 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 Myb_Cef PF11831.3 KFM14011.1 - 7.1e-74 247.9 3.5 7.1e-74 247.9 2.4 3.7 4 0 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 KFM14011.1 - 9.1e-18 64.0 7.1 2.8e-09 36.8 0.3 3.4 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFM14011.1 - 8.9e-17 60.9 8.1 3.6e-12 46.1 2.5 3.3 2 1 1 3 3 3 2 Myb-like DNA-binding domain TFIID-18kDa PF02269.11 KFM14012.1 - 2e-29 101.2 0.3 5.4e-29 99.8 0.2 1.8 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit DUF2849 PF11011.3 KFM14012.1 - 0.099 12.9 0.1 0.26 11.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2849) GST_N_3 PF13417.1 KFM14015.1 - 6.4e-09 35.9 0.0 1.1e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFM14015.1 - 1.3e-06 28.1 0.0 3.1e-06 26.9 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KFM14015.1 - 2e-05 24.5 0.0 3.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KFM14015.1 - 0.00025 21.4 0.1 0.00061 20.2 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KFM14015.1 - 0.0016 18.3 0.9 0.032 14.2 0.0 2.8 2 2 0 3 3 3 1 Glutathione S-transferase, C-terminal domain Phosphodiest PF01663.17 KFM14017.1 - 4.7e-77 259.7 0.9 5.5e-77 259.5 0.6 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KFM14017.1 - 3.3e-07 29.7 0.0 0.00057 19.1 0.0 2.3 1 1 0 2 2 2 2 Sulfatase Metalloenzyme PF01676.13 KFM14017.1 - 0.00097 18.5 0.0 0.0024 17.2 0.0 1.6 2 0 0 2 2 2 1 Metalloenzyme superfamily PglZ PF08665.7 KFM14017.1 - 0.13 11.9 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 PglZ domain Phosphodiest PF01663.17 KFM14018.1 - 7.5e-80 268.9 3.3 8.7e-80 268.7 2.3 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KFM14018.1 - 6.3e-07 28.8 0.0 0.019 14.1 0.0 2.5 2 1 0 2 2 2 2 Sulfatase Metalloenzyme PF01676.13 KFM14018.1 - 0.0069 15.8 0.0 0.014 14.7 0.0 1.6 2 0 0 2 2 2 1 Metalloenzyme superfamily UPF0126 PF03458.8 KFM14018.1 - 0.075 12.6 0.2 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 UPF0126 domain Calcipressin PF04847.7 KFM14019.1 - 2.3e-60 203.3 0.3 2.8e-60 203.0 0.2 1.1 1 0 0 1 1 1 1 Calcipressin RRM_5 PF13893.1 KFM14019.1 - 0.0019 18.0 0.0 0.0029 17.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFM14019.1 - 0.011 15.3 0.3 0.022 14.3 0.2 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) p450 PF00067.17 KFM14020.1 - 1.5e-57 195.1 0.1 2.5e-57 194.4 0.1 1.3 1 1 0 1 1 1 1 Cytochrome P450 Mito_carr PF00153.22 KFM14021.1 - 8.3e-64 211.3 1.0 1.4e-21 75.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein TUDOR PF00567.19 KFM14022.1 - 1.7e-149 489.5 4.2 8.7e-32 109.5 0.3 7.6 7 0 0 7 7 7 7 Tudor domain SMN PF06003.7 KFM14022.1 - 4e-14 52.3 0.5 0.0017 17.5 0.0 4.6 4 0 0 4 4 4 3 Survival motor neuron protein (SMN) DUF4537 PF15057.1 KFM14022.1 - 5.1e-09 35.9 0.5 0.091 12.5 0.0 5.9 6 0 0 6 6 6 2 Domain of unknown function (DUF4537) Agenet PF05641.7 KFM14022.1 - 0.00083 19.4 6.9 19 5.4 0.0 6.4 6 0 0 6 6 6 2 Agenet domain Pneumo_matrix PF03393.11 KFM14022.1 - 0.12 11.3 0.0 0.23 10.3 0.0 1.4 1 0 0 1 1 1 0 Pneumovirus matrix protein PAF-AH_p_II PF03403.8 KFM14024.1 - 2e-178 592.4 0.0 2.4e-178 592.1 0.0 1.0 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 KFM14024.1 - 1.1e-14 54.3 0.0 1.7e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KFM14024.1 - 2.2e-08 33.3 0.1 4.7e-07 28.9 0.0 2.1 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 KFM14024.1 - 7.2e-06 25.0 0.0 0.022 13.5 0.0 2.3 2 0 0 2 2 2 2 Chlorophyllase Peptidase_S9 PF00326.16 KFM14024.1 - 0.00011 21.5 0.0 0.00036 19.8 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KFM14024.1 - 0.0002 21.3 0.0 0.00051 19.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KFM14024.1 - 0.007 15.8 0.0 0.2 11.0 0.0 2.3 2 0 0 2 2 2 1 Putative esterase DLH PF01738.13 KFM14024.1 - 0.0099 15.1 0.0 0.082 12.1 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 KFM14024.1 - 0.022 14.1 0.0 0.44 9.9 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 KFM14024.1 - 0.033 13.7 0.0 0.068 12.7 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 KFM14024.1 - 0.068 12.7 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 Lipase (class 3) AXE1 PF05448.7 KFM14024.1 - 0.07 11.6 0.0 0.6 8.5 0.0 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DUF4499 PF14934.1 KFM14024.1 - 0.086 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4499) Ank_2 PF12796.2 KFM14025.1 - 6.4e-24 84.1 0.1 1.4e-18 67.0 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFM14025.1 - 2.1e-16 58.8 1.1 3.6e-08 32.8 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 KFM14025.1 - 3.4e-14 51.5 0.4 1.6e-05 24.6 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 KFM14025.1 - 3.4e-14 52.5 1.3 1.9e-07 31.0 0.0 3.9 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFM14025.1 - 7.9e-14 51.7 0.2 3.9e-10 39.9 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Astacin PF01400.19 KFM14026.1 - 9.3e-66 220.8 0.0 1.4e-65 220.2 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) MAM PF00629.18 KFM14026.1 - 1.6e-37 128.7 0.2 2.4e-37 128.1 0.1 1.3 1 0 0 1 1 1 1 MAM domain MATH PF00917.21 KFM14026.1 - 1.4e-25 89.8 1.1 4.6e-25 88.1 0.1 2.3 2 0 0 2 2 2 1 MATH domain EGF PF00008.22 KFM14026.1 - 1.8e-09 37.3 5.1 6.1e-09 35.6 3.5 2.0 1 0 0 1 1 1 1 EGF-like domain EGF_CA PF07645.10 KFM14026.1 - 0.065 13.2 6.6 0.18 11.8 4.5 1.7 1 0 0 1 1 1 0 Calcium-binding EGF domain 7tm_2 PF00002.19 KFM14027.1 - 4e-35 121.0 21.0 4e-35 121.0 14.5 1.7 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) I-set PF07679.11 KFM14027.1 - 1.4e-16 60.1 4.1 3.7e-10 39.5 0.1 2.7 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFM14027.1 - 2.1e-14 53.4 25.5 1.4e-09 37.9 0.3 4.8 3 1 1 4 4 4 2 Immunoglobulin domain GPS PF01825.16 KFM14027.1 - 1.5e-13 50.6 3.2 1.5e-13 50.6 2.2 2.3 2 0 0 2 2 2 1 Latrophilin/CL-1-like GPS domain ig PF00047.20 KFM14027.1 - 9.2e-13 48.1 6.5 2.6e-09 37.0 0.2 4.1 2 1 0 2 2 2 2 Immunoglobulin domain SEA PF01390.15 KFM14027.1 - 8.7e-12 44.6 0.9 3.2e-11 42.8 0.1 2.4 2 0 0 2 2 2 1 SEA domain V-set PF07686.12 KFM14027.1 - 7.2e-09 35.5 15.3 4.2e-08 33.0 0.8 3.5 3 1 0 3 3 3 2 Immunoglobulin V-set domain DUF3497 PF12003.3 KFM14027.1 - 3.8e-07 29.7 1.3 8.1e-07 28.6 0.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3497) Ig_3 PF13927.1 KFM14027.1 - 1.3e-05 25.5 24.1 0.0002 21.8 0.8 4.7 4 1 0 4 4 4 2 Immunoglobulin domain SH3_9 PF14604.1 KFM14030.1 - 2.1e-45 152.0 5.3 9e-16 57.1 0.1 3.5 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.23 KFM14030.1 - 2.2e-38 129.4 9.5 9.6e-13 47.3 0.1 3.4 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.12 KFM14030.1 - 3.7e-35 119.1 4.5 8e-12 44.4 0.1 3.6 3 0 0 3 3 3 3 Variant SH3 domain RabGAP-TBC PF00566.13 KFM14033.1 - 7.4e-49 166.1 1.4 7.4e-49 166.1 1.0 1.4 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Bacteroid_pep PF14406.1 KFM14033.1 - 0.09 12.9 0.3 0.27 11.4 0.2 1.8 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Bacteroidetes DAGK_cat PF00781.19 KFM14035.1 - 1.5e-24 85.9 0.0 2.3e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain GRAM PF02893.15 KFM14036.1 - 3.4e-16 58.5 0.1 6.5e-16 57.6 0.1 1.5 1 0 0 1 1 1 1 GRAM domain PRT_C PF08372.5 KFM14036.1 - 0.00012 21.6 0.0 0.00028 20.4 0.0 1.6 1 0 0 1 1 1 1 Plant phosphoribosyltransferase C-terminal Tmemb_cc2 PF10267.4 KFM14036.1 - 0.00066 18.3 3.1 0.0023 16.5 2.5 1.6 2 0 0 2 2 2 1 Predicted transmembrane and coiled-coil 2 protein NUDE_C PF04880.8 KFM14036.1 - 0.29 11.4 5.6 0.74 10.1 3.7 1.8 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region Histone PF00125.19 KFM14037.1 - 4.8e-26 90.6 0.1 6.8e-26 90.1 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFM14037.1 - 1.1e-06 28.5 0.7 2.3e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KFM14037.1 - 0.0028 17.8 0.0 0.0049 17.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A GTSE1_N PF15259.1 KFM14038.1 - 3e-51 173.1 3.8 3e-51 173.1 2.6 3.0 4 0 0 4 4 4 1 G-2 and S-phase expressed 1 CGI-121 PF08617.5 KFM14039.1 - 2.4e-43 147.5 1.2 2.7e-43 147.4 0.8 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 DIE2_ALG10 PF04922.7 KFM14040.1 - 7.2e-143 476.1 30.7 9.4e-143 475.8 21.3 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family Kinesin PF00225.18 KFM14041.1 - 1.2e-107 359.4 0.4 1.2e-107 359.4 0.3 3.2 3 1 1 4 4 4 1 Kinesin motor domain WD40 PF00400.27 KFM14041.1 - 3.2e-41 137.7 4.9 1.4e-07 31.1 0.1 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat ABC_membrane_2 PF06472.10 KFM14042.1 - 3.2e-106 354.5 4.7 4.1e-106 354.2 3.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KFM14042.1 - 2.9e-18 66.4 0.0 5.5e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KFM14042.1 - 0.00039 20.4 0.0 0.00071 19.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KFM14042.1 - 0.0029 17.1 0.0 0.0068 15.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 KFM14042.1 - 0.0053 17.0 1.2 0.01 16.2 0.0 2.1 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KFM14042.1 - 0.013 15.4 0.0 0.035 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.14 KFM14042.1 - 0.029 13.6 0.1 0.18 10.9 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Rad17 PF03215.10 KFM14042.1 - 0.035 12.7 0.0 0.058 12.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Adeno_IVa2 PF02456.10 KFM14042.1 - 0.059 12.0 0.0 0.098 11.2 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein MutS_V PF00488.16 KFM14042.1 - 0.087 12.2 0.1 0.26 10.6 0.0 1.8 2 0 0 2 2 2 0 MutS domain V Sugar_tr PF00083.19 KFM14043.1 - 1.9e-90 303.6 15.2 1.4e-67 228.2 1.7 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KFM14043.1 - 4.3e-15 55.2 23.9 2.8e-07 29.5 1.9 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 KFM14043.1 - 0.0015 16.9 2.5 0.0015 16.9 1.8 2.0 2 1 0 2 2 2 1 MFS/sugar transport protein Ral PF11058.3 KFM14043.1 - 0.098 12.0 1.1 0.19 11.1 0.7 1.4 1 0 0 1 1 1 0 Antirestriction protein Ral Pkinase PF00069.20 KFM14044.1 - 1.8e-44 151.8 0.0 5e-44 150.4 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM14044.1 - 1.5e-40 138.9 0.0 6.9e-40 136.7 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase LRR_8 PF13855.1 KFM14044.1 - 2e-27 94.6 37.8 5.2e-09 35.7 5.0 6.2 4 1 1 5 5 5 5 Leucine rich repeat Miro PF08477.8 KFM14044.1 - 2e-26 92.8 0.0 5.8e-26 91.3 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein LRR_4 PF12799.2 KFM14044.1 - 9.1e-26 89.0 44.8 1.1e-08 34.4 0.4 8.6 5 2 2 8 8 8 7 Leucine Rich repeats (2 copies) Ras PF00071.17 KFM14044.1 - 2.3e-15 56.3 0.0 6e-15 54.9 0.0 1.7 1 0 0 1 1 1 1 Ras family LRR_1 PF00560.28 KFM14044.1 - 3.1e-08 32.5 44.3 0.38 10.9 0.0 12.4 13 0 0 13 13 11 2 Leucine Rich Repeat Arf PF00025.16 KFM14044.1 - 1.7e-07 30.6 0.6 4.3e-07 29.3 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family Ank_2 PF12796.2 KFM14044.1 - 0.00016 21.9 3.5 0.0019 18.5 0.5 3.8 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) LRR_7 PF13504.1 KFM14044.1 - 0.00021 20.9 36.5 0.91 10.0 0.0 11.3 12 0 0 12 12 8 2 Leucine rich repeat Gtr1_RagA PF04670.7 KFM14044.1 - 0.00034 19.8 0.0 0.00086 18.5 0.0 1.7 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region T2SE PF00437.15 KFM14044.1 - 0.00077 18.4 0.0 0.0079 15.1 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein LRR_6 PF13516.1 KFM14044.1 - 0.0015 18.4 44.5 2.3 8.5 0.3 12.3 9 2 3 12 12 12 1 Leucine Rich repeat AAA_17 PF13207.1 KFM14044.1 - 0.0049 17.6 0.9 0.025 15.4 0.0 2.8 3 0 0 3 3 1 1 AAA domain PduV-EutP PF10662.4 KFM14044.1 - 0.0071 15.8 0.4 0.018 14.5 0.3 1.7 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 KFM14044.1 - 0.0082 16.2 0.0 0.039 14.1 0.0 2.2 1 0 0 1 1 1 1 AAA domain Ank PF00023.25 KFM14044.1 - 0.01 15.6 0.2 15 5.5 0.0 4.1 3 0 0 3 3 3 0 Ankyrin repeat ABC_tran PF00005.22 KFM14044.1 - 0.011 16.0 0.2 0.036 14.3 0.1 1.9 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 KFM14044.1 - 0.012 15.9 1.5 0.63 10.3 0.0 3.5 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.18 KFM14044.1 - 0.013 15.4 0.0 0.041 13.8 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase TrwB_AAD_bind PF10412.4 KFM14044.1 - 0.017 13.7 0.1 0.039 12.5 0.0 1.6 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.13 KFM14044.1 - 0.018 14.5 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family MobB PF03205.9 KFM14044.1 - 0.018 14.7 0.1 0.056 13.1 0.1 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Arm PF00514.18 KFM14044.1 - 0.024 14.4 6.1 0.17 11.7 0.1 4.8 5 0 0 5 5 4 0 Armadillo/beta-catenin-like repeat Ank_4 PF13637.1 KFM14044.1 - 0.031 14.7 0.0 0.37 11.3 0.0 3.0 1 1 1 2 2 2 0 Ankyrin repeats (many copies) AAA_18 PF13238.1 KFM14044.1 - 0.033 14.5 0.0 0.19 12.0 0.0 2.4 1 0 0 1 1 1 0 AAA domain Kdo PF06293.9 KFM14044.1 - 0.066 12.2 0.1 0.17 10.9 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AAA_29 PF13555.1 KFM14044.1 - 0.08 12.4 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 KFM14044.1 - 0.098 12.5 0.0 0.29 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KFM14044.1 - 0.17 11.2 0.1 0.47 9.8 0.1 1.7 1 0 0 1 1 1 0 AAA-like domain PQQ_2 PF13360.1 KFM14044.1 - 0.78 9.1 0.0 1.4 8.3 0.0 1.3 1 0 0 1 1 1 0 PQQ-like domain COPIIcoated_ERV PF07970.7 KFM14045.1 - 4e-47 160.6 0.4 5.9e-47 160.1 0.3 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KFM14045.1 - 3.3e-20 71.8 0.4 8.1e-20 70.6 0.2 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) dUTPase PF00692.14 KFM14046.1 - 1.1e-24 86.3 0.0 1.7e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 dUTPase RVP PF00077.15 KFM14046.1 - 0.0014 18.4 0.0 0.0031 17.3 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Laminin_EGF PF00053.19 KFM14047.1 - 1e-115 377.4 261.5 2.9e-12 46.3 9.7 13.6 13 0 0 13 13 13 13 Laminin EGF-like (Domains III and V) Laminin_N PF00055.12 KFM14047.1 - 2e-67 226.6 0.1 2e-67 226.6 0.1 2.0 2 0 0 2 2 2 1 Laminin N-terminal (Domain VI) APG17 PF04108.7 KFM14047.1 - 0.53 9.0 47.7 0.08 11.7 3.2 3.8 2 1 1 3 3 3 0 Autophagy protein Apg17 Pyr_redox_2 PF07992.9 KFM14048.1 - 5.6e-42 143.8 8.2 2e-41 142.0 5.7 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KFM14048.1 - 5.5e-41 139.0 0.1 5.5e-41 139.0 0.1 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 KFM14048.1 - 3.9e-19 68.8 6.6 3e-17 62.7 1.0 3.0 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFM14048.1 - 8.7e-11 42.2 0.8 4e-05 23.7 0.7 2.7 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KFM14048.1 - 6.7e-09 35.3 0.1 6.7e-09 35.3 0.1 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFM14048.1 - 1e-07 31.1 8.7 6.2e-07 28.6 0.3 3.2 3 1 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.1 KFM14048.1 - 1.5e-07 31.2 2.0 0.00016 21.6 0.1 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KFM14048.1 - 2.4e-06 26.6 11.1 7e-06 25.1 3.6 3.0 2 1 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 KFM14048.1 - 5.4e-05 22.4 4.1 0.01 14.8 0.1 3.3 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.12 KFM14048.1 - 7.1e-05 22.0 1.1 0.00027 20.1 0.0 2.3 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.1 KFM14048.1 - 0.00013 20.9 2.3 0.11 11.3 0.2 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 KFM14048.1 - 0.00014 20.4 11.6 0.0014 17.1 0.3 3.7 4 0 0 4 4 4 2 HI0933-like protein AlaDh_PNT_C PF01262.16 KFM14048.1 - 0.0018 17.8 4.8 0.081 12.4 0.2 2.8 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 KFM14048.1 - 0.0072 15.7 5.8 1.4 8.2 0.1 3.4 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.19 KFM14048.1 - 0.01 14.7 13.4 0.094 11.5 0.1 3.6 4 0 0 4 4 4 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KFM14048.1 - 0.022 14.4 5.1 0.51 9.9 0.7 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UPF0227 PF05728.7 KFM14048.1 - 0.088 12.5 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) GFO_IDH_MocA PF01408.17 KFM14048.1 - 0.83 10.1 4.6 53 4.3 0.1 3.7 4 0 0 4 4 4 0 Oxidoreductase family, NAD-binding Rossmann fold zf-C3HC4_3 PF13920.1 KFM14049.1 - 0.00024 20.6 7.5 0.00055 19.5 5.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFM14049.1 - 0.00067 19.6 9.3 0.0017 18.3 6.4 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFM14049.1 - 0.001 18.6 8.7 0.0022 17.6 6.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFM14049.1 - 0.0018 17.9 7.8 0.0038 16.9 5.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KFM14049.1 - 0.03 14.1 7.9 0.069 12.9 5.5 1.7 1 0 0 1 1 1 0 Ring finger domain zf-MIZ PF02891.15 KFM14049.1 - 0.045 13.2 6.6 0.1 12.1 4.6 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DZR PF12773.2 KFM14049.1 - 0.053 13.3 7.5 0.2 11.5 5.2 1.9 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_4 PF14570.1 KFM14049.1 - 1.4 8.5 8.2 3.9 7.1 5.7 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain C1_4 PF07975.7 KFM14049.1 - 5.9 6.9 11.6 5.2 7.1 6.4 2.3 2 1 0 2 2 2 0 TFIIH C1-like domain Sulfate_transp PF00916.15 KFM14050.1 - 1.5e-66 224.2 12.4 1.5e-66 224.2 8.6 2.1 2 1 1 3 3 3 1 Sulfate transporter family STAS PF01740.16 KFM14050.1 - 1.9e-33 114.3 0.5 4.1e-33 113.2 0.4 1.6 1 0 0 1 1 1 1 STAS domain Sulfate_tra_GLY PF13792.1 KFM14050.1 - 1e-27 95.6 3.2 1e-27 95.6 2.2 3.7 5 0 0 5 5 5 1 Sulfate transporter N-terminal domain with GLY motif 7tm_6 PF02949.15 KFM14050.1 - 0.056 12.2 1.3 2.4 6.9 0.0 2.4 2 0 0 2 2 2 0 7tm Odorant receptor Bap31 PF05529.7 KFM14051.1 - 1.6e-34 119.0 15.9 3.5e-34 117.9 11.0 1.5 1 1 0 1 1 1 1 B-cell receptor-associated protein 31-like DUF948 PF06103.6 KFM14051.1 - 0.0023 17.7 5.1 0.64 9.9 0.6 2.7 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF948) MscS_porin PF12795.2 KFM14051.1 - 0.0027 17.0 10.8 0.0034 16.7 7.5 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain TBPIP PF07106.8 KFM14051.1 - 0.0032 17.0 12.1 0.005 16.3 8.4 1.2 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HALZ PF02183.13 KFM14051.1 - 0.0064 16.1 10.9 0.41 10.4 1.4 3.3 3 0 0 3 3 3 2 Homeobox associated leucine zipper DUF3450 PF11932.3 KFM14051.1 - 0.0072 15.6 9.0 0.014 14.6 6.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) ADIP PF11559.3 KFM14051.1 - 0.0076 16.1 12.8 0.014 15.2 8.9 1.5 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Tropomyosin_1 PF12718.2 KFM14051.1 - 0.012 15.5 17.5 0.017 14.9 12.1 1.2 1 0 0 1 1 1 0 Tropomyosin like APG6 PF04111.7 KFM14051.1 - 0.014 14.4 15.7 0.02 13.9 10.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_13 PF13166.1 KFM14051.1 - 0.015 13.8 7.6 0.015 13.8 5.2 1.1 1 0 0 1 1 1 0 AAA domain HOOK PF05622.7 KFM14051.1 - 0.016 13.0 12.2 0.019 12.8 8.5 1.1 1 0 0 1 1 1 0 HOOK protein GAS PF13851.1 KFM14051.1 - 0.022 13.9 15.7 0.038 13.1 10.9 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.7 KFM14051.1 - 0.026 14.3 5.4 0.03 14.1 2.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Filament PF00038.16 KFM14051.1 - 0.029 13.8 13.0 0.053 12.9 9.0 1.4 1 1 0 1 1 1 0 Intermediate filament protein CCDC155 PF14662.1 KFM14051.1 - 0.045 13.3 13.0 0.066 12.8 9.0 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 Macoilin PF09726.4 KFM14051.1 - 0.048 11.9 8.1 0.064 11.5 5.6 1.2 1 0 0 1 1 1 0 Transmembrane protein AATF-Che1 PF13339.1 KFM14051.1 - 0.056 13.6 11.8 0.11 12.6 7.9 1.7 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor C9orf72-like PF15019.1 KFM14051.1 - 0.066 12.4 1.1 0.26 10.4 0.2 2.0 1 1 1 2 2 2 0 C9orf72-like protein family Reo_sigmaC PF04582.7 KFM14051.1 - 0.11 11.6 1.5 0.15 11.1 1.0 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF972 PF06156.8 KFM14051.1 - 0.16 12.3 17.1 0.85 10.0 2.6 2.6 2 1 1 3 3 2 0 Protein of unknown function (DUF972) UPF0449 PF15136.1 KFM14051.1 - 0.21 11.7 9.2 0.098 12.8 2.5 2.6 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 Atg14 PF10186.4 KFM14051.1 - 0.28 10.1 11.6 0.36 9.7 8.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 End3 PF12761.2 KFM14051.1 - 0.37 10.4 9.8 0.53 9.9 6.8 1.2 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 SYCE1 PF15233.1 KFM14051.1 - 0.38 10.6 11.3 0.13 12.1 2.6 2.4 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 Selenoprotein_S PF06936.6 KFM14051.1 - 0.4 10.1 5.6 0.48 9.9 3.9 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) Cep57_MT_bd PF06657.8 KFM14051.1 - 0.41 10.6 7.6 0.9 9.5 4.5 2.1 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Lzipper-MIP1 PF14389.1 KFM14051.1 - 0.41 10.7 9.5 0.21 11.6 2.4 2.4 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF4140 PF13600.1 KFM14051.1 - 0.43 11.0 10.8 0.13 12.7 2.3 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF342 PF03961.8 KFM14051.1 - 0.44 8.8 9.4 0.57 8.5 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF911 PF06023.7 KFM14051.1 - 0.44 9.6 2.7 0.57 9.3 1.6 1.4 1 1 0 1 1 1 0 Archaeal protein of unknown function (DUF911) Syntaxin_2 PF14523.1 KFM14051.1 - 0.55 10.2 8.0 4.9 7.2 5.0 2.2 1 1 1 2 2 2 0 Syntaxin-like protein Uds1 PF15456.1 KFM14051.1 - 0.59 10.1 14.7 0.52 10.3 7.8 2.3 1 1 1 2 2 2 0 Up-regulated During Septation DUF2317 PF10079.4 KFM14051.1 - 0.59 8.6 9.8 0.83 8.1 6.6 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) DUF106 PF01956.11 KFM14051.1 - 0.73 9.3 9.6 2.2 7.7 5.1 2.5 1 1 1 2 2 2 0 Integral membrane protein DUF106 Syntaxin PF00804.20 KFM14051.1 - 0.78 9.9 8.4 1.4 9.0 5.8 1.4 1 0 0 1 1 1 0 Syntaxin DUF1192 PF06698.6 KFM14051.1 - 1.3 8.9 6.5 2 8.2 0.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) DUF3373 PF11853.3 KFM14051.1 - 1.5 7.2 6.4 1.9 6.9 4.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3373) IncA PF04156.9 KFM14051.1 - 1.9 8.0 13.0 4.4 6.8 9.0 1.6 1 1 0 1 1 1 0 IncA protein bZIP_Maf PF03131.12 KFM14051.1 - 2.3 8.5 11.1 9.4 6.6 0.3 3.1 1 1 2 3 3 3 0 bZIP Maf transcription factor Cep57_CLD_2 PF14197.1 KFM14051.1 - 2.4 8.1 14.1 1.2 9.1 7.0 2.4 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Cluap1 PF10234.4 KFM14051.1 - 2.6 7.1 14.7 5 6.2 10.2 1.6 1 1 0 1 1 1 0 Clusterin-associated protein-1 Seryl_tRNA_N PF02403.17 KFM14051.1 - 3.7 7.5 14.6 19 5.3 10.1 2.2 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Exonuc_VII_L PF02601.10 KFM14051.1 - 4 6.5 9.8 6.4 5.8 6.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4164 PF13747.1 KFM14051.1 - 4.2 7.5 11.5 7.2 6.8 7.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) TMF_DNA_bd PF12329.3 KFM14051.1 - 4.3 7.2 21.7 4.5 7.1 8.2 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Mnd1 PF03962.10 KFM14051.1 - 4.8 6.8 15.1 11 5.6 10.5 1.6 1 1 0 1 1 1 0 Mnd1 family Tho2 PF11262.3 KFM14051.1 - 5.4 5.9 8.3 7.7 5.4 5.7 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Dus PF01207.12 KFM14052.1 - 4e-73 245.9 0.3 4.8e-73 245.6 0.2 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Oxidored_FMN PF00724.15 KFM14052.1 - 4.3e-05 22.6 0.0 7.1e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family His_biosynth PF00977.16 KFM14052.1 - 0.00033 20.0 0.0 0.00099 18.4 0.0 1.5 1 1 0 1 1 1 1 Histidine biosynthesis protein TMP-TENI PF02581.12 KFM14052.1 - 0.0035 16.4 0.0 0.0068 15.5 0.0 1.5 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI ThiG PF05690.9 KFM14052.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG COG5 PF10392.4 KFM14053.1 - 2.7e-31 108.2 2.2 2.7e-31 108.2 1.6 2.9 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Vps51 PF08700.6 KFM14053.1 - 4.1e-09 36.1 4.0 6e-09 35.6 0.1 3.3 3 1 1 4 4 4 1 Vps51/Vps67 COG2 PF06148.6 KFM14053.1 - 0.00074 19.3 0.5 0.00074 19.3 0.4 3.6 4 1 0 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF4461 PF14688.1 KFM14053.1 - 0.026 13.8 3.6 0.83 8.9 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4461) DUF2450 PF10475.4 KFM14053.1 - 0.1 11.4 8.4 0.033 13.1 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) 7tm_1 PF00001.16 KFM14054.1 - 1.4e-25 89.9 21.0 2.2e-25 89.2 14.5 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pex24p PF06398.6 KFM14054.1 - 0.25 10.0 13.7 0.018 13.8 5.4 2.0 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin AXH PF08517.7 KFM14055.1 - 2.5e-42 143.6 0.0 5.3e-42 142.6 0.0 1.6 1 0 0 1 1 1 1 Ataxin-1 and HBP1 module (AXH) HMG_box PF00505.14 KFM14055.1 - 9.6e-15 54.6 0.8 1.8e-14 53.7 0.5 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFM14055.1 - 4.6e-09 36.5 2.0 9.3e-09 35.5 1.4 1.5 1 0 0 1 1 1 1 HMG-box domain MAT_Alpha1 PF04769.7 KFM14055.1 - 0.014 14.6 0.3 0.025 13.9 0.2 1.3 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 cNMP_binding PF00027.24 KFM14056.1 - 1e-40 137.4 0.1 7.2e-22 77.0 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain PI3Ka PF00613.15 KFM14057.1 - 8e-63 210.9 1.5 8e-63 210.9 1.0 1.8 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 KFM14057.1 - 4.6e-54 183.3 0.4 9.3e-54 182.3 0.2 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 KFM14057.1 - 3.5e-28 98.1 0.7 1e-27 96.6 0.1 2.0 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.13 KFM14057.1 - 2.1e-27 95.1 6.4 2.2e-26 91.8 0.0 3.7 4 0 0 4 4 4 1 PI3-kinase family, ras-binding domain BMFP PF04380.8 KFM14057.1 - 0.032 14.3 1.0 1.1 9.5 0.0 3.2 3 0 0 3 3 3 0 Membrane fusogenic activity COX5A PF02284.11 KFM14057.1 - 0.082 12.8 0.2 0.69 9.8 0.0 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Va Ras PF00071.17 KFM14058.1 - 7.7e-18 64.4 0.5 9e-18 64.1 0.3 1.1 1 0 0 1 1 1 1 Ras family Beta-Casp PF10996.3 KFM14058.1 - 0.092 12.6 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Beta-Casp domain NAPRTase PF04095.11 KFM14059.1 - 2e-80 269.6 0.0 2.7e-80 269.2 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family MARVEL PF01284.18 KFM14061.1 - 9.8e-35 119.4 14.4 1.4e-34 119.0 10.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF4418 PF14387.1 KFM14061.1 - 0.013 15.2 2.5 0.026 14.2 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4418) Mtp PF03821.11 KFM14061.1 - 0.015 14.7 0.2 0.019 14.3 0.1 1.3 1 0 0 1 1 1 0 Golgi 4-transmembrane spanning transporter DUF4173 PF13777.1 KFM14061.1 - 4 6.6 9.6 0.6 9.3 3.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4173) DUF1201 PF06716.6 KFM14061.1 - 6.9 6.5 11.4 1.3 8.8 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1201) Cadherin PF00028.12 KFM14062.1 - 6.9e-60 199.3 4.7 1.1e-16 60.8 0.1 6.3 6 0 0 6 6 6 6 Cadherin domain Cadherin_2 PF08266.7 KFM14062.1 - 7.8e-10 38.1 0.0 1.7e-08 33.9 0.0 3.1 3 1 0 3 3 3 1 Cadherin-like SCA7 PF08313.7 KFM14063.1 - 5.6e-28 96.3 4.9 6.4e-28 96.1 2.4 1.9 2 0 0 2 2 2 1 SCA7, zinc-binding domain DUF3505 PF12013.3 KFM14063.1 - 0.073 13.3 1.9 0.32 11.2 1.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3505) EF-hand_7 PF13499.1 KFM14064.1 - 0.033 14.3 0.0 0.036 14.2 0.0 1.2 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.1 KFM14064.1 - 0.05 13.5 0.0 0.099 12.5 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain RINT1_TIP1 PF04437.8 KFM14065.1 - 3.6e-159 530.4 13.5 3.6e-159 530.4 9.3 2.1 2 0 0 2 2 2 2 RINT-1 / TIP-1 family VacA2 PF03077.9 KFM14065.1 - 0.16 11.6 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Putative vacuolating cytotoxin TruD PF01142.13 KFM14066.1 - 1.4e-67 227.9 0.0 2.4e-65 220.6 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) R3H PF01424.17 KFM14066.1 - 0.035 13.8 0.0 0.09 12.4 0.0 1.7 1 0 0 1 1 1 0 R3H domain XPG_I_2 PF12813.2 KFM14066.1 - 0.066 12.6 0.1 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 XPG domain containing Pkinase PF00069.20 KFM14067.1 - 1.8e-34 119.0 8.4 4.7e-23 81.6 0.7 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFM14067.1 - 2e-13 50.0 0.1 6.3e-10 38.5 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase SET PF00856.23 KFM14068.1 - 2.5e-10 40.8 0.1 2.5e-10 40.8 0.1 3.9 2 2 0 2 2 2 1 SET domain PHD PF00628.24 KFM14068.1 - 1.5e-09 37.3 12.0 3.6e-09 36.1 8.3 1.7 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KFM14068.1 - 0.0051 16.1 8.2 0.011 15.0 5.7 1.6 1 0 0 1 1 1 1 PHD-finger L_HGMIC_fpl PF10242.4 KFM14069.1 - 1.6e-28 99.9 5.8 1.7e-28 99.8 4.0 1.0 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.1 KFM14069.1 - 0.01 15.5 4.0 0.011 15.4 2.8 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF4064 PF13273.1 KFM14069.1 - 0.029 14.4 0.5 0.031 14.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF2701 PF10857.3 KFM14069.1 - 2.3 8.0 7.4 0.81 9.5 3.5 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2701) ORC5_C PF14630.1 KFM14070.1 - 1.9e-79 266.9 0.2 3e-79 266.2 0.0 1.4 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 KFM14070.1 - 1.5e-10 41.3 0.0 2.9e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFM14070.1 - 2.8e-08 33.9 0.1 1.1e-06 28.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain Kinesin PF00225.18 KFM14070.1 - 0.0015 17.2 0.6 0.0051 15.5 0.4 1.8 1 1 1 2 2 2 1 Kinesin motor domain Arch_ATPase PF01637.13 KFM14070.1 - 0.002 17.8 0.0 0.0036 17.0 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 KFM14070.1 - 0.0095 15.8 0.2 0.21 11.4 0.1 2.4 1 1 0 1 1 1 1 AAA domain PIF1 PF05970.9 KFM14070.1 - 0.044 12.7 0.0 0.11 11.4 0.0 1.6 2 0 0 2 2 2 0 PIF1-like helicase Bac_DnaA PF00308.13 KFM14070.1 - 0.059 12.9 0.1 0.23 11.0 0.0 1.7 1 1 1 2 2 2 0 Bacterial dnaA protein AAA_10 PF12846.2 KFM14070.1 - 0.072 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain FtsK_SpoIIIE PF01580.13 KFM14070.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SE PF00437.15 KFM14070.1 - 0.14 11.0 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_17 PF13207.1 KFM14070.1 - 0.15 12.8 0.0 0.4 11.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain Sulfate_transp PF00916.15 KFM14071.1 - 3.2e-71 239.6 17.7 5.8e-71 238.7 11.8 1.8 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KFM14071.1 - 2.2e-30 104.1 3.6 2.2e-30 104.1 2.5 3.6 5 0 0 5 5 5 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KFM14071.1 - 1.7e-27 95.1 0.1 3.2e-27 94.2 0.0 1.5 1 0 0 1 1 1 1 STAS domain AAA PF00004.24 KFM14072.1 - 5.7e-41 139.8 0.0 2.5e-40 137.7 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFM14072.1 - 6.4e-06 26.3 0.0 0.00071 19.7 0.0 2.8 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 KFM14072.1 - 0.00015 21.4 0.1 0.0011 18.6 0.0 2.5 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KFM14072.1 - 0.0016 18.4 0.0 0.0081 16.1 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KFM14072.1 - 0.0017 19.1 0.1 0.0053 17.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KFM14072.1 - 0.0029 17.5 0.0 0.0092 15.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KFM14072.1 - 0.0044 15.9 0.0 0.013 14.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 KFM14072.1 - 0.0055 16.4 0.1 0.01 15.5 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 KFM14072.1 - 0.0057 16.5 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KFM14072.1 - 0.0095 15.9 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KFM14072.1 - 0.0097 14.9 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Sigma54_activ_2 PF14532.1 KFM14072.1 - 0.01 15.9 0.0 0.027 14.5 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 KFM14072.1 - 0.015 14.7 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 KFM14072.1 - 0.019 14.0 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.1 KFM14072.1 - 0.026 14.4 0.0 0.054 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KFM14072.1 - 0.036 14.3 0.0 0.086 13.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.16 KFM14072.1 - 0.051 12.7 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 KFM14072.1 - 0.065 11.9 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus RNA_helicase PF00910.17 KFM14072.1 - 0.074 13.2 0.0 0.24 11.5 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA_25 PF13481.1 KFM14072.1 - 0.079 12.3 0.0 0.44 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 KFM14072.1 - 0.09 12.3 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KFM14072.1 - 0.14 11.6 0.0 0.38 10.2 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Myb_DNA-binding PF00249.26 KFM14073.1 - 1.4e-17 63.4 0.2 4.3e-10 39.4 0.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain DnaJ PF00226.26 KFM14073.1 - 7.4e-17 60.8 0.1 7.4e-17 60.8 0.1 2.7 2 0 0 2 2 2 1 DnaJ domain Myb_DNA-bind_6 PF13921.1 KFM14073.1 - 9.9e-10 38.3 5.7 6.6e-06 26.1 0.1 3.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain Peptidase_M16 PF00675.15 KFM14074.1 - 1e-57 194.0 0.2 1.5e-57 193.5 0.1 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KFM14074.1 - 9.9e-44 149.2 0.0 7.3e-43 146.3 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain Lactamase_B_2 PF12706.2 KFM14075.1 - 2.3e-40 138.2 0.1 3e-40 137.8 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KFM14075.1 - 4.2e-14 52.5 0.0 7e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KFM14075.1 - 0.0014 18.3 0.9 0.063 12.9 0.3 2.5 3 0 0 3 3 3 1 Metallo-beta-lactamase superfamily Arm_2 PF04826.8 KFM14076.1 - 2.4e-69 233.2 6.6 2.7e-69 233.1 4.6 1.0 1 0 0 1 1 1 1 Armadillo-like Arm PF00514.18 KFM14076.1 - 3.1e-08 33.1 1.4 0.039 13.8 0.1 3.5 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFM14076.1 - 9.2e-06 25.8 0.0 0.0053 17.0 0.0 2.1 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.17 KFM14076.1 - 9.7e-05 22.1 0.1 0.19 11.9 0.0 3.3 3 0 0 3 3 3 1 HEAT repeat PUL PF08324.6 KFM14076.1 - 0.0021 16.9 2.6 0.0051 15.6 1.5 1.7 1 1 1 2 2 2 1 PUL domain Yae1_N PF09811.4 KFM14077.1 - 9e-10 37.9 23.0 0.0097 15.4 15.9 2.8 1 1 0 1 1 1 1 Essential protein Yae1, N terminal LRR_6 PF13516.1 KFM14078.1 - 1.6e-29 98.6 23.1 0.031 14.3 0.4 14.8 16 0 0 16 16 16 7 Leucine Rich repeat LRR_4 PF12799.2 KFM14078.1 - 1e-17 63.3 10.3 0.00038 20.0 0.0 8.4 7 1 0 8 8 8 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM14078.1 - 8.8e-15 52.4 23.2 1 9.6 0.0 13.9 10 4 4 14 14 14 4 Leucine Rich Repeat LRR_8 PF13855.1 KFM14078.1 - 1.5e-12 47.1 21.5 0.00055 19.6 3.2 7.0 5 4 3 8 8 8 5 Leucine rich repeat LRR_7 PF13504.1 KFM14078.1 - 4.8e-07 28.9 22.5 1.9 9.0 0.1 11.5 13 0 0 13 13 13 2 Leucine rich repeat F-box-like PF12937.2 KFM14078.1 - 2.3e-05 24.0 0.9 5.7e-05 22.7 0.6 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFM14078.1 - 0.00078 19.0 0.2 0.0026 17.3 0.1 1.9 1 0 0 1 1 1 1 F-box domain YbaB_DNA_bd PF02575.11 KFM14078.1 - 0.097 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 YbaB/EbfC DNA-binding family Ste50p-SAM PF09235.5 KFM14078.1 - 1 9.4 12.9 68 3.5 0.1 6.3 5 3 2 7 7 7 0 Ste50p, sterile alpha motif LRR_8 PF13855.1 KFM14079.1 - 5.2e-41 138.2 41.2 3.8e-12 45.7 3.3 4.5 2 2 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.2 KFM14079.1 - 1.3e-16 59.8 25.1 6.8e-08 31.9 1.9 5.6 4 1 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFM14079.1 - 1.7e-13 50.3 0.5 6.9e-07 29.0 0.1 2.3 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_1 PF00560.28 KFM14079.1 - 7.1e-10 37.5 24.6 0.025 14.5 0.5 8.5 9 0 0 9 9 9 5 Leucine Rich Repeat LRR_9 PF14580.1 KFM14079.1 - 2.6e-09 36.8 4.8 0.0002 21.0 0.1 2.2 2 0 0 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.1 KFM14079.1 - 4.2e-07 29.3 18.8 0.55 10.4 1.6 6.5 6 0 0 6 6 6 4 Leucine Rich repeat LRR_7 PF13504.1 KFM14079.1 - 0.061 13.5 24.4 0.71 10.3 0.5 7.6 8 0 0 8 8 8 0 Leucine rich repeat DUF4098 PF13345.1 KFM14080.1 - 7.5e-17 61.0 27.1 2.9e-10 39.9 3.9 4.1 2 1 1 4 4 4 3 Domain of unknown function (DUF4098) DUF2807 PF10988.3 KFM14080.1 - 0.0016 18.0 2.6 0.0016 18.0 1.8 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF2807) DUF4097 PF13349.1 KFM14080.1 - 0.012 15.1 16.2 0.062 12.8 4.5 3.1 2 2 1 3 3 3 0 Domain of unknown function (DUF4097) CRA PF06589.6 KFM14081.1 - 1 8.6 12.7 3.7 6.8 1.0 3.7 3 0 0 3 3 3 0 Circumsporozoite-related antigen (CRA) Fibrinogen_C PF00147.13 KFM14082.1 - 2.5e-82 276.0 9.8 3.3e-82 275.6 6.8 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain FlaC_arch PF05377.6 KFM14082.1 - 0.00019 21.2 2.3 0.0093 15.8 0.5 2.7 3 0 0 3 3 3 1 Flagella accessory protein C (FlaC) Exonuc_VII_L PF02601.10 KFM14082.1 - 0.023 13.8 1.7 0.029 13.5 1.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Lzipper-MIP1 PF14389.1 KFM14082.1 - 0.042 13.9 2.7 2.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF1978 PF09321.5 KFM14082.1 - 0.051 13.0 4.7 0.094 12.1 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) DUF16 PF01519.11 KFM14082.1 - 0.073 13.3 3.7 0.16 12.1 2.6 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF16 Prefoldin PF02996.12 KFM14082.1 - 0.22 11.1 6.5 3.1 7.4 0.3 2.4 2 0 0 2 2 2 0 Prefoldin subunit Laminin_II PF06009.7 KFM14082.1 - 0.31 10.7 8.2 0.21 11.3 2.6 2.1 2 0 0 2 2 2 0 Laminin Domain II Uds1 PF15456.1 KFM14082.1 - 0.33 10.9 6.5 0.68 9.9 4.5 1.5 1 0 0 1 1 1 0 Up-regulated During Septation PEP-utilisers_N PF05524.8 KFM14082.1 - 0.37 10.6 2.5 3 7.6 0.2 2.2 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal TPR_MLP1_2 PF07926.7 KFM14082.1 - 0.49 10.1 8.7 3.7 7.3 1.2 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 KFM14082.1 - 0.61 9.6 8.9 0.67 9.5 0.5 2.1 1 1 1 2 2 2 0 IncA protein Syntaxin PF00804.20 KFM14082.1 - 1.7 8.8 7.9 5.9 7.1 5.5 2.0 1 1 0 1 1 1 0 Syntaxin DivIVA PF05103.8 KFM14082.1 - 3.8 7.5 8.0 8.8 6.3 5.5 1.5 1 1 0 1 1 1 0 DivIVA protein HR1 PF02185.11 KFM14082.1 - 6.6 6.5 9.9 1 9.1 2.6 2.4 2 0 0 2 2 2 0 Hr1 repeat GSAP-16 PF14959.1 KFM14083.1 - 2.4e-42 143.2 0.1 1.2e-41 141.0 0.0 2.2 2 0 0 2 2 2 1 gamma-Secretase-activating protein C-term Y_phosphatase PF00102.22 KFM14084.1 - 1.1e-83 280.1 0.2 1.3e-83 279.9 0.2 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFM14084.1 - 0.00076 19.0 0.1 0.0019 17.8 0.0 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFM14084.1 - 0.00082 19.6 0.0 0.0015 18.8 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KFM14084.1 - 0.011 15.8 2.4 0.015 15.3 0.0 2.3 3 1 0 3 3 3 0 Inositol hexakisphosphate Tmemb_185A PF10269.4 KFM14086.1 - 1.3e-09 38.0 20.1 8.4e-06 25.5 7.6 2.0 1 1 1 2 2 2 2 Transmembrane Fragile-X-F protein DUF3522 PF12036.3 KFM14086.1 - 0.053 13.3 5.2 0.076 12.8 3.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3522) DUF1275 PF06912.6 KFM14086.1 - 1.8 7.7 6.7 0.94 8.6 1.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1275) CoA_binding_3 PF13727.1 KFM14086.1 - 1.9 8.2 14.2 0.068 12.9 3.9 2.0 1 1 1 2 2 2 0 CoA-binding domain DUF1430 PF07242.6 KFM14086.1 - 4.2 7.4 9.1 7.3 6.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) Phtf-FEM1B_bdg PF12129.3 KFM14087.1 - 2e-79 264.5 0.2 2e-79 264.5 0.1 2.1 2 0 0 2 2 2 1 Male germ-cell putative homeodomain transcription factor PDZ PF00595.19 KFM14088.1 - 6.1e-61 202.5 10.0 3.1e-15 56.0 0.0 5.5 5 0 0 5 5 5 5 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM14088.1 - 3.7e-30 103.6 0.2 2.9e-05 23.8 0.0 5.3 5 0 0 5 5 5 5 PDZ domain WW PF00397.21 KFM14088.1 - 1.5e-15 56.6 7.4 4.7e-09 35.9 0.2 3.1 3 0 0 3 3 3 2 WW domain Guanylate_kin PF00625.16 KFM14088.1 - 6.8e-09 35.4 0.0 1.3e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase Tricorn_PDZ PF14685.1 KFM14088.1 - 6.8e-07 28.9 2.2 1.3 8.8 0.0 5.0 5 0 0 5 5 5 3 Tricorn protease PDZ domain YodL PF14191.1 KFM14088.1 - 0.084 13.3 0.0 0.3 11.5 0.0 1.9 1 0 0 1 1 1 0 YodL-like Costars PF14705.1 KFM14089.1 - 1.2e-32 111.7 0.1 1.4e-32 111.4 0.1 1.1 1 0 0 1 1 1 1 Costars DcpS_C PF11969.3 KFM14090.1 - 8.2e-23 80.8 0.1 9.4e-23 80.6 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 KFM14090.1 - 5e-07 30.1 1.4 1.2e-06 28.9 1.0 1.6 1 1 0 1 1 1 1 HIT domain TLD PF07534.11 KFM14091.1 - 7.3e-41 139.4 0.7 8.6e-41 139.1 0.5 1.0 1 0 0 1 1 1 1 TLD HD_3 PF13023.1 KFM14093.1 - 1.3e-46 158.3 1.8 1.5e-46 158.1 1.2 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 KFM14093.1 - 4.6e-05 23.4 0.4 7.7e-05 22.6 0.3 1.4 1 0 0 1 1 1 1 HD domain DUF4259 PF14078.1 KFM14093.1 - 0.0082 16.6 0.2 0.013 16.0 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4259) HDOD PF08668.7 KFM14093.1 - 0.092 12.0 0.1 0.13 11.4 0.1 1.2 1 0 0 1 1 1 0 HDOD domain FERM_M PF00373.13 KFM14093.1 - 0.24 11.5 1.9 0.37 10.9 1.3 1.2 1 0 0 1 1 1 0 FERM central domain TPD52 PF04201.10 KFM14094.1 - 2.1e-61 206.4 4.4 2.9e-61 205.9 3.0 1.2 1 0 0 1 1 1 1 Tumour protein D52 family DUF2656 PF10847.3 KFM14094.1 - 0.058 13.3 0.3 0.093 12.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2656) Rifin_STEVOR PF02009.11 KFM14094.1 - 0.19 11.3 2.1 0.17 11.5 0.6 1.5 2 0 0 2 2 2 0 Rifin/stevor family IBR PF01485.16 KFM14095.1 - 5.9e-17 61.3 28.4 8.1e-09 35.2 5.9 3.0 3 0 0 3 3 3 2 IBR domain IncA PF04156.9 KFM14095.1 - 0.018 14.6 1.5 0.026 14.1 1.0 1.3 1 0 0 1 1 1 0 IncA protein NKAIN PF05640.9 KFM14096.1 - 5.1e-47 159.4 0.0 5.6e-47 159.3 0.0 1.0 1 0 0 1 1 1 1 Na,K-Atpase Interacting protein NKAIN PF05640.9 KFM14097.1 - 7.4e-24 83.8 2.5 7.9e-24 83.7 1.7 1.0 1 0 0 1 1 1 1 Na,K-Atpase Interacting protein Asp-B-Hydro_N PF05279.6 KFM14099.1 - 5.9e-07 29.5 1.9 5.9e-07 29.5 1.3 2.2 2 0 0 2 2 2 1 Aspartyl beta-hydroxylase N-terminal region FGF-BP1 PF06473.7 KFM14099.1 - 1 8.8 16.7 2.5 7.6 11.6 1.5 1 1 1 2 2 2 0 FGF binding protein 1 (FGF-BP1) Neur_chan_memb PF02932.11 KFM14099.1 - 5.7 6.7 10.8 9.7 5.9 7.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CRAL_TRIO PF00650.15 KFM14100.1 - 9.2e-35 119.4 0.0 1.7e-34 118.6 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 KFM14100.1 - 8.4e-09 35.4 0.0 1.4e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KFM14100.1 - 3.1e-07 30.4 0.1 8.9e-07 28.9 0.1 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Lipocalin PF00061.18 KFM14101.1 - 7.7e-22 77.8 1.7 8.4e-22 77.7 1.2 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.1 KFM14101.1 - 0.011 15.4 0.4 0.029 14.0 0.2 1.6 1 1 1 2 2 2 0 Lipocalin / cytosolic fatty-acid binding protein family DBP10CT PF08147.7 KFM14101.1 - 0.075 12.8 0.5 0.28 11.0 0.1 1.9 2 0 0 2 2 2 0 DBP10CT (NUC160) domain PKI PF02827.11 KFM14102.1 - 6.8e-23 80.5 0.1 7.3e-23 80.4 0.1 1.0 1 0 0 1 1 1 1 cAMP-dependent protein kinase inhibitor Serinc PF03348.10 KFM14103.1 - 3.7e-181 602.5 13.2 4.2e-181 602.3 9.2 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Vert_HS_TF PF06546.6 KFM14104.1 - 2.1e-80 269.9 28.7 2.3e-74 250.1 13.3 2.2 1 1 1 2 2 2 2 Vertebrate heat shock transcription factor HSF_DNA-bind PF00447.12 KFM14104.1 - 2.6e-27 95.0 0.4 5.7e-27 93.9 0.3 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding bZIP_2 PF07716.10 KFM14104.1 - 0.024 14.4 1.8 0.061 13.1 1.2 1.7 1 0 0 1 1 1 0 Basic region leucine zipper APG6 PF04111.7 KFM14104.1 - 0.025 13.6 3.0 0.041 12.9 2.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 HALZ PF02183.13 KFM14104.1 - 0.028 14.1 0.7 0.071 12.8 0.5 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper Ribosomal_L29 PF00831.18 KFM14105.1 - 9e-07 28.4 0.2 2.2e-06 27.2 0.1 1.7 1 0 0 1 1 1 1 Ribosomal L29 protein Connexin PF00029.14 KFM14106.1 - 2.7e-50 168.9 0.1 6.5e-50 167.6 0.1 1.6 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 KFM14106.1 - 1.3e-31 108.1 2.9 3.3e-31 106.9 2.0 1.7 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain Connexin43 PF03508.8 KFM14106.1 - 8.8e-12 44.0 15.8 1.8e-11 42.9 11.0 1.6 1 0 0 1 1 1 1 Gap junction alpha-1 protein (Cx43) TMEM154 PF15102.1 KFM14106.1 - 0.038 13.7 0.0 11 5.7 0.0 2.3 2 0 0 2 2 2 0 TMEM154 protein family BROMI PF14961.1 KFM14108.1 - 0 1963.3 19.8 0 1963.2 13.7 1.0 1 0 0 1 1 1 1 Broad-minded protein RabGAP-TBC PF00566.13 KFM14108.1 - 0.005 16.3 5.8 0.0054 16.2 2.5 2.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Methyltransf_27 PF13708.1 KFM14108.1 - 0.016 14.7 0.0 0.15 11.5 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Glyco_hydro_47 PF01532.15 KFM14110.1 - 9.3e-153 509.0 0.0 1.1e-152 508.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_88 PF07470.8 KFM14110.1 - 0.025 13.6 0.7 0.099 11.6 0.1 2.2 3 0 0 3 3 3 0 Glycosyl Hydrolase Family 88 MCM PF00493.18 KFM14112.1 - 1.9e-106 355.6 0.0 2.8e-106 355.0 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 KFM14112.1 - 5.9e-09 35.3 0.1 0.00028 20.1 0.0 2.8 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KFM14112.1 - 1.8e-07 30.9 0.0 3.8e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM_N PF14551.1 KFM14112.1 - 0.0003 21.2 0.0 0.0023 18.3 0.0 2.2 2 0 0 2 2 2 1 MCM N-terminal domain AAA_3 PF07726.6 KFM14112.1 - 0.013 15.1 0.0 0.03 13.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFM14112.1 - 0.064 13.3 0.0 0.21 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 KFM14112.1 - 0.081 12.3 0.0 7.3 6.0 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Rota_NS6 PF04866.7 KFM14112.1 - 9.8 6.2 6.5 30 4.7 0.1 3.3 2 1 0 3 3 3 0 Rotavirus non-structural protein 6 ASF1_hist_chap PF04729.8 KFM14113.1 - 1.3e-69 232.7 0.2 1.6e-69 232.4 0.1 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone UPF0154 PF03672.8 KFM14113.1 - 0.051 13.2 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) Phospholamban PF04272.9 KFM14115.1 - 2.2e-37 126.2 9.4 2.3e-37 126.1 6.5 1.0 1 0 0 1 1 1 1 Phospholamban Sarcolipin PF05366.6 KFM14115.1 - 0.0069 15.7 5.9 0.013 14.8 4.1 1.5 1 1 0 1 1 1 1 Sarcolipin DUF1705 PF08019.7 KFM14115.1 - 0.027 13.9 0.4 0.027 13.9 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1705) DUF914 PF06027.7 KFM14116.1 - 4.3e-133 443.3 11.3 4.9e-133 443.1 7.8 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 KFM14116.1 - 7.6e-13 48.5 23.7 3.3e-07 30.3 7.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 KFM14116.1 - 0.00026 20.6 19.3 0.019 14.6 6.3 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family Mg_trans_NIPA PF05653.9 KFM14116.1 - 0.0015 17.5 2.5 0.0015 17.5 1.7 2.0 1 1 0 2 2 2 1 Magnesium transporter NIPA UAA PF08449.6 KFM14116.1 - 0.0049 15.8 14.7 0.0076 15.1 10.2 1.2 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.1 KFM14116.1 - 0.025 14.7 6.5 0.025 14.7 4.5 2.6 2 1 0 2 2 2 0 Multidrug resistance efflux transporter DUF809 PF05663.6 KFM14116.1 - 0.098 12.5 0.1 0.098 12.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF809) RVT_1 PF00078.22 KFM14117.1 - 0.0053 16.1 0.0 0.0085 15.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Prenyltransf PF01255.14 KFM14118.1 - 6.3e-08 32.0 0.0 7.1e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF3369 PF11849.3 KFM14118.1 - 0.019 14.9 0.3 0.025 14.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3369) Methyltransf_12 PF08242.7 KFM14118.1 - 0.029 14.8 0.1 0.045 14.2 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 KFM14118.1 - 0.07 13.6 0.2 0.11 12.9 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 KFM14118.1 - 0.087 13.1 0.2 0.13 12.6 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain LRR_8 PF13855.1 KFM14119.1 - 2.2e-51 171.4 53.4 2.2e-12 46.5 0.4 7.6 2 1 7 9 9 9 9 Leucine rich repeat LRR_4 PF12799.2 KFM14119.1 - 2.1e-42 142.0 53.5 3.2e-08 33.0 1.3 10.4 5 5 6 11 11 11 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFM14119.1 - 6.4e-25 83.3 42.5 0.023 14.6 0.0 16.0 15 2 1 16 16 16 9 Leucine Rich Repeat LRR_7 PF13504.1 KFM14119.1 - 9.2e-14 49.1 51.3 0.28 11.5 0.1 15.5 17 0 0 17 17 17 6 Leucine rich repeat LRR_5 PF13306.1 KFM14119.1 - 1.1e-10 41.2 6.7 1.9e-06 27.6 0.2 4.4 2 2 0 4 4 4 2 Leucine rich repeats (6 copies) LRR_6 PF13516.1 KFM14119.1 - 1.3e-06 27.8 58.5 0.52 10.5 0.3 14.0 13 3 3 16 16 16 5 Leucine Rich repeat LRR_9 PF14580.1 KFM14119.1 - 1.6e-06 27.8 17.6 0.065 12.7 0.3 5.1 1 1 2 5 5 5 3 Leucine-rich repeat PDZ PF00595.19 KFM14120.1 - 7.1e-18 64.5 0.5 1.9e-17 63.1 0.3 1.8 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFM14120.1 - 5.6e-05 22.9 0.4 0.00018 21.3 0.0 2.1 2 1 0 2 2 2 1 PDZ domain bZIP_2 PF07716.10 KFM14120.1 - 0.0083 15.9 7.6 0.0083 15.9 5.3 2.9 2 0 0 2 2 2 1 Basic region leucine zipper DUF903 PF06004.7 KFM14120.1 - 0.067 12.7 0.1 0.15 11.5 0.1 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF903) DUF4200 PF13863.1 KFM14120.1 - 0.42 10.5 11.8 0.86 9.5 8.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF4254 PF14063.1 KFM14120.1 - 0.66 9.5 7.4 1.4 8.5 5.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) DivIC PF04977.10 KFM14120.1 - 0.77 9.2 12.3 1.1 8.7 1.8 2.8 2 0 0 2 2 2 0 Septum formation initiator Atg14 PF10186.4 KFM14120.1 - 2.3 7.0 14.4 14 4.5 10.0 1.9 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3071 PF11268.3 KFM14120.1 - 3 7.5 6.5 25 4.5 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3071) DUF4140 PF13600.1 KFM14120.1 - 4.7 7.7 13.0 1.5 9.3 3.1 2.9 2 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) F5_F8_type_C PF00754.20 KFM14121.1 - 3e-27 94.9 4.0 3e-27 94.9 2.8 1.9 2 0 0 2 2 2 1 F5/8 type C domain LCCL PF03815.14 KFM14121.1 - 2.2e-18 65.9 0.3 5.2e-18 64.8 0.2 1.6 1 0 0 1 1 1 1 LCCL domain CUB PF00431.15 KFM14121.1 - 9.1e-18 64.3 0.5 2.8e-17 62.7 0.0 2.1 3 0 0 3 3 3 1 CUB domain Pkinase_Tyr PF07714.12 KFM14122.1 - 1.3e-97 325.8 0.0 2.5e-97 325.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM14122.1 - 4.4e-44 150.5 0.0 7.1e-44 149.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.16 KFM14122.1 - 2.6e-43 146.0 34.5 2.3e-09 37.2 0.4 9.7 9 0 0 9 9 9 7 Fibronectin type III domain DUF2627 PF11118.3 KFM14122.1 - 0.26 11.3 0.0 0.65 10.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) RFX_DNA_binding PF02257.10 KFM14123.1 - 1.6e-27 95.4 0.2 4.4e-27 94.0 0.2 1.8 1 0 0 1 1 1 1 RFX DNA-binding domain RAG2_PHD PF13341.1 KFM14123.1 - 0.046 13.6 0.0 0.16 11.9 0.0 1.9 1 0 0 1 1 1 0 RAG2 PHD domain DUF1075 PF06388.6 KFM14124.1 - 1.1e-48 164.6 1.1 1.2e-48 164.4 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1075) Arm PF00514.18 KFM14125.1 - 5.2e-89 289.3 14.4 1.1e-12 47.2 0.0 8.7 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFM14125.1 - 4.4e-30 103.7 0.0 2.8e-08 33.9 0.0 5.4 3 1 2 5 5 5 4 HEAT repeats IBB PF01749.15 KFM14125.1 - 2.7e-28 97.9 1.7 6.2e-28 96.8 1.2 1.7 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 KFM14125.1 - 7.7e-25 86.7 2.5 3.1e-07 30.6 0.0 6.0 5 1 1 6 6 6 5 HEAT-like repeat HEAT PF02985.17 KFM14125.1 - 2.7e-18 64.3 10.5 6.7e-05 22.6 0.0 8.9 9 1 0 9 9 8 4 HEAT repeat RICTOR_V PF14668.1 KFM14125.1 - 2e-06 27.6 0.9 1.3 9.0 0.0 5.1 4 3 2 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 Arm_2 PF04826.8 KFM14125.1 - 2.3e-06 26.9 0.0 0.025 13.6 0.0 2.8 1 1 1 2 2 2 2 Armadillo-like V-ATPase_H_C PF11698.3 KFM14125.1 - 5.9e-05 22.9 0.0 0.34 10.8 0.0 4.4 2 1 2 4 4 4 2 V-ATPase subunit H Adaptin_N PF01602.15 KFM14125.1 - 0.0002 19.8 0.0 0.0037 15.6 0.0 2.4 1 1 1 2 2 2 2 Adaptin N terminal region Proteasom_PSMB PF10508.4 KFM14125.1 - 0.0036 15.6 0.1 0.65 8.1 0.0 2.8 2 1 1 3 3 3 1 Proteasome non-ATPase 26S subunit HEAT_PBS PF03130.11 KFM14125.1 - 0.0058 16.9 2.3 5.4 7.7 0.0 5.0 6 0 0 6 6 5 1 PBS lyase HEAT-like repeat CLASP_N PF12348.3 KFM14125.1 - 0.11 11.8 0.0 0.3 10.4 0.0 1.7 2 0 0 2 2 2 0 CLASP N terminal Peptidase_C78 PF07910.8 KFM14126.1 - 2.9e-73 245.6 0.0 4.4e-73 245.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.14 KFM14126.1 - 0.028 13.5 0.0 0.055 12.5 0.0 1.5 1 0 0 1 1 1 0 Peptidase family C54 DUF2233 PF09992.4 KFM14126.1 - 0.077 13.0 0.0 0.25 11.3 0.0 1.8 1 1 1 2 2 2 0 Predicted periplasmic protein (DUF2233) RWD PF05773.17 KFM14127.1 - 5.9e-16 58.3 0.3 1.4e-15 57.1 0.2 1.6 1 0 0 1 1 1 1 RWD domain DUF445 PF04286.7 KFM14127.1 - 0.01 15.4 8.6 0.012 15.2 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF2135 PF09906.4 KFM14127.1 - 0.08 12.9 0.9 0.17 11.8 0.6 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2135) EAP30 PF04157.11 KFM14127.1 - 0.12 11.5 3.2 0.18 10.9 2.2 1.4 1 0 0 1 1 1 0 EAP30/Vps36 family GOLD_2 PF13897.1 KFM14127.1 - 0.18 12.0 1.7 0.3 11.2 0.8 1.7 1 1 0 1 1 1 0 Golgi-dynamics membrane-trafficking Folliculin PF11704.3 KFM14127.1 - 0.36 10.3 4.2 0.72 9.4 2.9 1.6 1 1 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF4484 PF14831.1 KFM14127.1 - 3.2 7.8 10.2 1 9.4 5.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4484) UPF0542 PF15086.1 KFM14127.1 - 6.1 6.6 6.0 9.7 5.9 0.4 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 Ca_hom_mod PF14798.1 KFM14128.1 - 8.1e-92 306.7 2.5 9.4e-92 306.5 1.7 1.0 1 0 0 1 1 1 1 Calcium homeostasis modulator DUF2093 PF09866.4 KFM14128.1 - 0.26 10.5 2.7 22 4.3 0.0 3.7 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2093) TRAPP PF04051.11 KFM14129.1 - 3.5e-35 120.7 0.0 4.1e-35 120.5 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Ca_hom_mod PF14798.1 KFM14130.1 - 5.6e-89 297.4 11.7 6.7e-89 297.1 8.1 1.1 1 0 0 1 1 1 1 Calcium homeostasis modulator ACOX PF01756.14 KFM14130.1 - 0.19 11.0 1.4 0.25 10.7 0.2 1.7 2 0 0 2 2 2 0 Acyl-CoA oxidase DltD_M PF04918.7 KFM14131.1 - 0.028 14.5 3.9 0.068 13.3 2.7 1.6 1 0 0 1 1 1 0 DltD central region DUF1673 PF07895.6 KFM14131.1 - 0.4 10.1 7.0 1.7 8.0 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) 5_nucleotid PF05761.9 KFM14132.1 - 5.9e-48 163.5 0.1 7.3e-48 163.2 0.1 1.0 1 0 0 1 1 1 1 5' nucleotidase family HAD_2 PF13419.1 KFM14132.1 - 0.0073 16.5 0.1 0.1 12.7 0.0 2.5 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Collagen PF01391.13 KFM14133.1 - 1.6e-69 229.3 286.1 5.1e-09 35.5 21.0 10.3 1 1 8 9 9 9 7 Collagen triple helix repeat (20 copies) C1q PF00386.16 KFM14133.1 - 3.6e-39 133.6 0.1 4.7e-39 133.2 0.0 1.1 1 0 0 1 1 1 1 C1q domain Pkinase_Tyr PF07714.12 KFM14134.1 - 1.8e-95 318.8 0.0 2.2e-95 318.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM14134.1 - 3.8e-48 163.9 0.0 4.8e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 KFM14134.1 - 1.6e-24 85.5 0.1 4.9e-24 83.9 0.1 1.8 2 0 0 2 2 2 1 SH2 domain APH PF01636.18 KFM14134.1 - 2.6e-05 24.1 0.0 0.12 12.0 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 KFM14134.1 - 0.001 18.1 0.0 0.0014 17.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like B2 PF11473.3 KFM14134.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 RNA binding protein B2 Sulfotransfer_1 PF00685.22 KFM14137.1 - 4.7e-35 121.1 0.2 5.9e-35 120.8 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_2 PF03567.9 KFM14137.1 - 0.0034 17.1 0.2 0.0053 16.4 0.2 1.3 1 0 0 1 1 1 1 Sulfotransferase family Hist_deacetyl PF00850.14 KFM14138.1 - 4.3e-81 272.6 0.1 6.2e-81 272.0 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Laminin_G_2 PF02210.19 KFM14140.1 - 2.3e-103 341.2 0.3 8.2e-25 87.3 0.1 5.5 5 0 0 5 5 5 5 Laminin G domain Laminin_G_1 PF00054.18 KFM14140.1 - 6.1e-75 249.4 0.0 4.5e-21 75.2 0.0 5.5 5 0 0 5 5 5 5 Laminin G domain Laminin_II PF06009.7 KFM14140.1 - 5.1e-33 113.7 2.0 5.1e-33 113.7 1.4 5.6 3 1 3 6 6 6 1 Laminin Domain II Laminin_I PF06008.9 KFM14140.1 - 8.6e-29 100.6 43.2 2.6e-28 99.0 17.5 3.7 2 2 2 4 4 4 2 Laminin Domain I Laminin_EGF PF00053.19 KFM14140.1 - 3.6e-22 78.0 66.3 8.7e-10 38.3 9.8 4.9 4 1 1 5 5 5 3 Laminin EGF-like (Domains III and V) Laminin_G_3 PF13385.1 KFM14140.1 - 3.4e-18 66.3 0.2 0.0001 22.5 0.0 5.2 5 0 0 5 5 5 3 Concanavalin A-like lectin/glucanases superfamily DUF3287 PF11690.3 KFM14140.1 - 0.3 11.1 3.6 1.3 9.1 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) AAA_25 PF13481.1 KFM14140.1 - 1.5 8.1 6.5 0.67 9.3 0.6 3.0 3 1 1 4 4 4 0 AAA domain Sec34 PF04136.10 KFM14140.1 - 4.5 6.9 17.0 0.48 10.1 4.2 3.4 1 1 2 3 3 3 0 Sec34-like family Tubulin PF00091.20 KFM14141.1 - 2.3e-72 243.3 0.0 3.3e-72 242.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFM14141.1 - 1.5e-29 102.5 0.0 2.5e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KFM14141.1 - 0.0044 16.5 0.0 0.0081 15.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain RNase_H2-Ydr279 PF09468.5 KFM14141.1 - 0.054 12.6 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) IGFBP PF00219.13 KFM14142.1 - 1.4e-12 47.9 21.9 1.4e-12 47.9 15.2 4.4 3 1 1 4 4 4 1 Insulin-like growth factor binding protein TSP_1 PF00090.14 KFM14142.1 - 1.7e-06 28.0 5.9 1.7e-06 28.0 4.1 2.7 2 0 0 2 2 2 1 Thrombospondin type 1 domain Cys_knot PF00007.17 KFM14142.1 - 4.5e-06 26.6 12.1 4.5e-06 26.6 8.4 3.4 2 1 1 3 3 3 1 Cystine-knot domain VWC PF00093.13 KFM14142.1 - 9.5e-05 22.4 0.2 9.5e-05 22.4 0.1 4.9 4 2 0 4 4 4 1 von Willebrand factor type C domain Pkinase_Tyr PF07714.12 KFM14144.1 - 2.2e-93 312.1 0.0 2.8e-93 311.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFM14144.1 - 4.9e-50 170.1 0.0 6.7e-50 169.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 KFM14144.1 - 2.1e-29 101.1 0.6 4.1e-29 100.1 0.2 1.7 2 0 0 2 2 2 1 SH2 domain SH3_1 PF00018.23 KFM14144.1 - 1.9e-21 75.1 0.4 1e-20 72.8 0.1 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KFM14144.1 - 2.5e-14 52.5 0.4 5.5e-14 51.4 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KFM14144.1 - 9.1e-13 47.4 0.0 3e-12 45.8 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain APH PF01636.18 KFM14144.1 - 0.011 15.4 0.0 0.055 13.1 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family SH3_3 PF08239.6 KFM14144.1 - 0.082 13.1 0.1 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain YcaO PF02624.11 KFM14144.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 YcaO-like family SEFIR PF08357.6 KFM14145.1 - 3.6e-33 114.7 0.2 4.7e-33 114.3 0.1 1.2 1 0 0 1 1 1 1 SEFIR domain TIR_2 PF13676.1 KFM14145.1 - 0.00078 19.5 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 TIR domain DNA_pol_B PF00136.16 KFM14146.1 - 2.2e-86 290.5 0.0 5e-86 289.3 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KFM14146.1 - 1.4e-22 79.9 0.0 1e-14 54.1 0.0 2.6 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KFM14146.1 - 2e-12 46.9 11.6 1.8e-11 43.9 8.0 2.9 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta MFS_1 PF07690.11 KFM14147.1 - 1e-14 54.0 44.2 1.2e-07 30.7 17.7 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Plasmodium_Vir PF05795.6 KFM14147.1 - 0.037 13.2 0.2 0.11 11.6 0.0 2.0 3 0 0 3 3 3 0 Plasmodium vivax Vir protein Pardaxin PF07425.6 KFM14147.1 - 0.097 12.0 1.3 0.39 10.1 0.9 2.0 1 0 0 1 1 1 0 Pardaxin MFS_1 PF07690.11 KFM14148.1 - 4e-36 124.4 42.9 4.9e-21 74.8 18.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3951 PF13131.1 KFM14148.1 - 1.4 8.7 6.7 0.26 11.1 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3951) Brix PF04427.13 KFM14149.1 - 6.3e-43 146.6 0.4 9.3e-43 146.1 0.3 1.2 1 0 0 1 1 1 1 Brix domain TFIIIC_sub6 PF10419.4 KFM14150.1 - 1.3e-14 53.2 0.0 2.3e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit SAM_decarbox PF01536.11 KFM14151.1 - 2.7e-110 368.1 2.3 3.1e-110 367.9 1.6 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Pkinase PF00069.20 KFM14152.1 - 9e-44 149.5 0.1 1.7e-43 148.6 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFM14152.1 - 1.8e-14 53.4 0.0 3.4e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFM14152.1 - 0.037 13.7 0.2 0.072 12.8 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 KFM14152.1 - 0.058 12.4 0.1 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sugar_tr PF00083.19 KFM14153.1 - 3.4e-26 91.8 26.5 4.6e-26 91.4 18.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFM14153.1 - 2.1e-22 79.3 57.2 2.3e-21 75.8 19.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DAO PF01266.19 KFM14154.1 - 1.5e-20 73.4 0.1 4.3e-20 71.9 0.1 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFM14154.1 - 0.00064 20.0 0.0 0.02 15.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFM14154.1 - 0.0034 16.2 0.0 0.023 13.5 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain UDPG_MGDP_dh_N PF03721.9 KFM14154.1 - 0.016 14.5 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.12 KFM14154.1 - 0.1 11.7 0.1 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_Gly3P_dh_N PF01210.18 KFM14154.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Methyltransf_22 PF13383.1 KFM14155.1 - 7.8e-15 55.0 0.2 9.2e-15 54.8 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.7 KFM14155.1 - 2.6e-06 27.4 0.0 3.8e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain WD40 PF00400.27 KFM14156.1 - 2.6e-43 144.3 16.5 6.5e-09 35.3 0.0 7.5 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 KFM14156.1 - 0.029 12.5 0.4 2.4 6.1 0.0 2.5 2 1 1 3 3 3 0 Nucleoporin Nup120/160 WH2 PF02205.15 KFM14157.1 - 1.5e-07 30.7 0.1 2.7e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 WH2 motif 7tm_1 PF00001.16 KFM14158.1 - 2.6e-38 131.6 17.2 3.1e-38 131.3 11.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) ADK PF00406.17 KFM14159.1 - 2.7e-12 46.7 0.3 7e-08 32.4 0.0 2.2 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.1 KFM14159.1 - 8e-09 36.3 0.2 1.2e-07 32.5 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KFM14159.1 - 1.4e-07 31.8 0.5 1.2e-06 28.8 0.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KFM14159.1 - 8.2e-05 22.6 0.1 0.00025 21.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain YHS PF04945.8 KFM14159.1 - 9.1e-05 22.2 2.9 0.0003 20.5 1.1 2.3 2 0 0 2 2 2 1 YHS domain AAA PF00004.24 KFM14159.1 - 0.00025 21.2 0.0 0.00045 20.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KFM14159.1 - 0.00037 20.3 0.0 0.0016 18.3 0.0 2.0 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KFM14159.1 - 0.00072 18.7 0.0 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.7 KFM14159.1 - 0.0056 16.3 0.0 0.035 13.7 0.0 2.0 2 0 0 2 2 2 1 NACHT domain DUF3508 PF12018.3 KFM14159.1 - 0.0084 15.1 0.1 0.0084 15.1 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3508) AAA_14 PF13173.1 KFM14159.1 - 0.0088 15.9 1.4 0.16 11.8 0.0 2.9 2 1 1 3 3 3 1 AAA domain SKI PF01202.17 KFM14159.1 - 0.018 14.9 0.7 0.059 13.2 0.0 2.1 2 1 1 3 3 3 0 Shikimate kinase UPF0079 PF02367.12 KFM14159.1 - 0.02 14.5 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 End3 PF12761.2 KFM14159.1 - 0.034 13.7 1.0 0.034 13.7 0.7 1.7 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 ABC_tran PF00005.22 KFM14159.1 - 0.035 14.3 0.5 0.085 13.1 0.4 1.8 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.1 KFM14159.1 - 0.051 13.7 0.2 0.28 11.3 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KFM14159.1 - 0.053 13.0 0.0 0.079 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KFM14159.1 - 0.055 13.4 0.1 0.12 12.3 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain Hydrolase_4 PF12146.3 KFM14159.1 - 0.07 12.9 0.0 0.21 11.4 0.0 1.7 2 0 0 2 2 2 0 Putative lysophospholipase AAA_5 PF07728.9 KFM14159.1 - 0.098 12.3 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Cytidylate_kin2 PF13189.1 KFM14159.1 - 0.13 12.1 0.8 0.46 10.3 0.6 1.9 1 1 0 1 1 1 0 Cytidylate kinase-like family CPT PF07931.7 KFM14159.1 - 0.16 11.5 0.0 0.32 10.6 0.0 1.4 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ADK PF00406.17 KFM14160.1 - 1.8e-17 63.6 0.0 3e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase YHS PF04945.8 KFM14160.1 - 1e-10 41.2 0.7 0.0075 16.0 0.0 3.4 3 0 0 3 3 3 3 YHS domain AAA_17 PF13207.1 KFM14160.1 - 4.7e-09 37.1 0.0 1.4e-08 35.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain DUF3508 PF12018.3 KFM14160.1 - 1.4e-05 24.2 0.5 0.0024 16.9 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3508) AAA_18 PF13238.1 KFM14160.1 - 0.00025 21.3 1.4 0.0031 17.8 0.1 2.7 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 KFM14160.1 - 0.0029 17.5 0.1 0.021 14.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KFM14160.1 - 0.0047 16.9 0.1 0.046 13.6 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 KFM14160.1 - 0.061 13.2 0.1 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KFM14160.1 - 0.064 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KFM14160.1 - 0.09 12.3 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 KFM14160.1 - 0.1 12.3 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B zf-H2C2_2 PF13465.1 KFM14161.1 - 6.1e-50 165.1 46.6 1.1e-09 38.0 0.7 9.6 9 1 0 9 9 9 7 Zinc-finger double domain zf-C2H2 PF00096.21 KFM14161.1 - 3.3e-38 127.7 62.8 3.9e-07 30.0 0.2 8.6 8 0 0 8 8 8 8 Zinc finger, C2H2 type BTB PF00651.26 KFM14161.1 - 2e-27 95.3 0.2 4.3e-27 94.2 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_4 PF13894.1 KFM14161.1 - 1.2e-23 81.6 52.5 0.00018 21.5 0.2 8.6 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFM14161.1 - 4.5e-15 55.3 39.9 0.015 15.4 0.5 9.5 10 0 0 10 10 10 7 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFM14161.1 - 8.5e-09 35.3 49.1 0.00044 20.3 0.2 8.7 8 0 0 8 8 8 5 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFM14161.1 - 2.8e-07 30.1 47.4 0.053 13.4 0.3 9.3 10 0 0 10 10 9 5 C2H2-type zinc finger zf-Di19 PF05605.7 KFM14161.1 - 6.4e-06 26.1 25.6 0.012 15.7 0.6 5.6 3 1 2 5 5 5 2 Drought induced 19 protein (Di19), zinc-binding C1_1 PF00130.17 KFM14161.1 - 7.4e-05 22.3 21.1 0.074 12.7 0.2 4.8 3 1 1 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-H2C2_5 PF13909.1 KFM14161.1 - 0.0095 16.1 35.8 0.082 13.1 1.4 7.3 6 0 0 6 6 6 2 C2H2-type zinc-finger domain DUF2180 PF09947.4 KFM14161.1 - 0.077 12.7 11.0 5.6 6.7 0.1 4.8 2 2 3 5 5 5 0 Uncharacterized protein conserved in archaea (DUF2180) zf-C2HC_2 PF13913.1 KFM14161.1 - 0.11 12.1 0.1 0.11 12.1 0.0 4.9 5 0 0 5 5 5 0 zinc-finger of a C2HC-type RRN7 PF11781.3 KFM14161.1 - 0.42 10.1 17.5 4.6 6.8 0.1 6.9 8 0 0 8 8 8 0 RNA polymerase I-specific transcription initiation factor Rrn7 XPA_N PF01286.13 KFM14161.1 - 2.3 7.9 31.1 3.1 7.5 0.3 6.6 7 0 0 7 7 6 0 XPA protein N-terminal zf-FCS PF06467.9 KFM14161.1 - 2.8 7.6 29.1 0.58 9.8 0.2 6.3 3 2 3 6 6 6 0 MYM-type Zinc finger with FCS sequence motif Pro_isomerase PF00160.16 KFM14162.1 - 1.4e-38 132.5 0.0 1.5e-38 132.4 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MGC-24 PF05283.6 KFM14163.1 - 1.6e-31 109.5 21.8 2.1e-31 109.1 15.1 1.1 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24) Herpes_gE PF02480.11 KFM14163.1 - 0.035 12.3 1.1 0.037 12.2 0.3 1.4 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E ABC2_membrane_3 PF12698.2 KFM14163.1 - 0.052 12.5 1.6 0.062 12.3 1.1 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein Adeno_E3_CR2 PF02439.10 KFM14163.1 - 0.052 13.0 0.3 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 CitMHS PF03600.11 KFM14163.1 - 0.06 11.9 1.7 0.074 11.6 1.2 1.1 1 0 0 1 1 1 0 Citrate transporter vMSA PF00695.14 KFM14163.1 - 0.11 11.6 2.4 0.14 11.2 1.7 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus TMEM154 PF15102.1 KFM14163.1 - 6.5 6.4 18.2 0.13 11.9 1.7 2.2 1 1 1 2 2 2 0 TMEM154 protein family DnaB_2 PF07261.6 KFM14165.1 - 0.071 12.7 1.2 0.2 11.2 0.2 2.3 2 0 0 2 2 2 0 Replication initiation and membrane attachment NPV_P10 PF05531.7 KFM14165.1 - 0.37 11.0 3.4 0.96 9.7 1.3 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Mto2_bdg PF12808.2 KFM14165.1 - 3.5 7.7 18.3 0.48 10.5 1.8 4.1 3 1 0 4 4 4 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF2935 PF11155.3 KFM14165.1 - 6.7 6.8 11.2 21 5.1 0.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) DUF4549 PF15082.1 KFM14167.1 - 6.2e-21 74.5 2.7 6.6e-21 74.4 1.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4549) Arm PF00514.18 KFM14168.1 - 8.5e-08 31.7 14.0 0.37 10.7 0.0 7.4 7 1 0 7 7 7 4 Armadillo/beta-catenin-like repeat KAP PF05804.7 KFM14168.1 - 2.7e-05 22.3 13.5 0.0068 14.3 1.1 2.9 2 2 0 2 2 2 2 Kinesin-associated protein (KAP) CTNNBL PF08216.6 KFM14168.1 - 6.8 6.3 10.6 18 4.9 0.1 4.5 5 2 2 7 7 7 0 Catenin-beta-like, Arm-motif containing nuclear