# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- OMP_b-brl_2 PF13568.1 KEG05098.1 - 0.013 15.3 0.1 0.015 15.1 0.1 1.1 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain DUF912 PF06024.7 KEG05098.1 - 0.043 13.8 0.0 0.06 13.4 0.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2207 PF09972.4 KEG05098.1 - 0.085 11.4 0.0 0.091 11.3 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MAP7 PF05672.6 KEG05099.1 - 0.012 14.9 68.9 0.014 14.8 47.7 1.0 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Fibrinogen_BP PF08017.6 KEG05099.1 - 0.027 12.6 35.2 0.029 12.5 24.4 1.0 1 0 0 1 1 1 0 Fibrinogen binding protein Peptidase_M8 PF01457.11 KEG05100.1 - 8.8e-09 34.2 0.0 9.7e-09 34.0 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin DUF4398 PF14346.1 KEG05101.1 - 0.21 11.6 6.3 0.28 11.2 4.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4398) DUF4094 PF13334.1 KEG05104.1 - 0.0066 16.8 0.2 0.011 16.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4094) DAP10 PF07213.6 KEG05104.1 - 5.6 6.8 6.2 8.8 6.1 4.3 1.4 1 0 0 1 1 1 0 DAP10 membrane protein KASH PF10541.4 KEG05106.1 - 8.2 6.3 8.0 22 5.0 5.5 1.8 1 1 0 1 1 1 0 Nuclear envelope localisation domain EphA2_TM PF14575.1 KEG05107.1 - 0.0075 16.6 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Orthoreo_P10 PF07204.6 KEG05107.1 - 0.066 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Herpes_gE PF02480.11 KEG05107.1 - 0.073 11.3 0.0 0.082 11.1 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E IncA PF04156.9 KEG05107.1 - 0.095 12.2 0.4 0.12 11.9 0.3 1.1 1 0 0 1 1 1 0 IncA protein DUF3481 PF11980.3 KEG05107.1 - 0.12 12.1 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) ATP_synth_reg PF14960.1 KEG05108.1 - 0.006 15.7 0.3 0.0083 15.2 0.2 1.3 1 0 0 1 1 1 1 ATP synthase regulation RskA PF10099.4 KEG05108.1 - 0.012 15.3 1.7 0.013 15.2 1.2 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA SNAP-25 PF00835.14 KEG05110.1 - 0.27 12.0 12.9 4.8 8.0 1.0 3.6 1 1 2 3 3 3 0 SNAP-25 family DUF3525 PF12039.3 KEG05110.1 - 10 4.5 8.1 11 4.3 5.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) Guanylate_cyc PF00211.15 KEG05112.1 - 0.017 14.4 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain Orthoreo_P10 PF07204.6 KEG05112.1 - 0.038 13.7 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 DUF3481 PF11980.3 KEG05112.1 - 0.052 13.3 0.0 0.071 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) ORC5_C PF14630.1 KEG05113.1 - 0.091 12.2 0.4 0.096 12.1 0.3 1.0 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus Peripla_BP_6 PF13458.1 KEG05114.1 - 0.007 15.7 0.1 0.0079 15.5 0.1 1.0 1 0 0 1 1 1 1 Periplasmic binding protein RVT_1 PF00078.22 KEG05115.1 - 2.7e-11 43.2 0.0 3.2e-11 42.9 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_transf_21 PF13506.1 KEG05116.1 - 0.045 13.0 0.0 0.049 12.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 21 HTH_29 PF13551.1 KEG05121.1 - 0.0012 18.9 1.8 0.042 14.0 0.1 2.2 1 1 1 2 2 2 2 Winged helix-turn helix Daxx PF03344.10 KEG05121.1 - 0.014 13.9 6.4 0.015 13.8 4.4 1.0 1 0 0 1 1 1 0 Daxx Family HTH_32 PF13565.1 KEG05121.1 - 0.11 13.2 1.6 12 6.7 0.2 2.2 1 1 1 2 2 2 0 Homeodomain-like domain BRCA2 PF00634.13 KEG05121.1 - 0.12 11.6 0.3 0.22 10.8 0.2 1.4 1 0 0 1 1 1 0 BRCA2 repeat DAZAP2 PF11029.3 KEG05122.1 - 0.21 12.0 3.2 0.24 11.8 2.2 1.1 1 0 0 1 1 1 0 DAZ associated protein 2 (DAZAP2) Herpes_DNAp_acc PF04929.7 KEG05122.1 - 0.68 8.8 7.6 0.86 8.4 5.3 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Chitin_bind_4 PF00379.18 KEG05122.1 - 1.7 8.9 6.4 32 4.8 2.1 2.9 2 1 0 2 2 2 0 Insect cuticle protein Selenoprotein_S PF06936.6 KEG05124.1 - 0.23 10.9 4.4 0.28 10.7 3.0 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) HpaP PF09483.5 KEG05125.1 - 1.1 9.1 6.5 1.4 8.8 4.5 1.1 1 0 0 1 1 1 0 Type III secretion protein (HpaP) DUF4398 PF14346.1 KEG05126.1 - 1 9.4 13.3 0.37 10.8 6.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4398) DUF948 PF06103.6 KEG05128.1 - 0.00017 21.3 8.6 0.094 12.5 1.9 2.3 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF948) DUF4164 PF13747.1 KEG05128.1 - 0.0025 17.9 30.5 0.47 10.6 4.6 3.9 1 1 2 3 3 3 1 Domain of unknown function (DUF4164) Rootletin PF15035.1 KEG05128.1 - 0.006 16.5 35.1 0.031 14.2 10.1 2.2 1 1 1 2 2 2 1 Ciliary rootlet component, centrosome cohesion Fe_dep_repress PF01325.14 KEG05128.1 - 0.0064 16.4 11.3 5.4 7.0 0.1 4.4 1 1 4 5 5 4 0 Iron dependent repressor, N-terminal DNA binding domain TMF_TATA_bd PF12325.3 KEG05128.1 - 0.0074 16.0 23.4 0.0074 16.0 16.2 2.2 1 1 1 2 2 2 1 TATA element modulatory factor 1 TATA binding Cast PF10174.4 KEG05128.1 - 0.0093 14.0 32.0 0.01 13.9 22.2 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone MCPsignal PF00015.16 KEG05128.1 - 0.01 15.4 5.8 0.0098 15.4 3.5 1.3 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain SlyX PF04102.7 KEG05128.1 - 0.019 15.3 9.3 0.019 15.3 6.4 2.9 1 1 2 3 3 3 0 SlyX CENP-F_leu_zip PF10473.4 KEG05128.1 - 0.031 14.1 41.4 0.36 10.7 11.8 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlgN PF05130.7 KEG05128.1 - 0.046 13.9 27.4 0.24 11.6 18.8 2.1 1 1 0 1 1 1 0 FlgN protein Nnf1 PF03980.9 KEG05128.1 - 0.14 12.1 30.5 0.1 12.6 2.7 4.3 1 1 4 6 6 6 0 Nnf1 GAS PF13851.1 KEG05128.1 - 0.15 11.2 35.8 1.9 7.6 15.2 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF641 PF04859.7 KEG05128.1 - 0.17 11.6 23.7 0.53 10.0 5.5 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) bZIP_1 PF00170.16 KEG05128.1 - 0.18 11.8 44.2 1.1 9.2 7.5 4.1 1 1 3 4 4 3 0 bZIP transcription factor DUF972 PF06156.8 KEG05128.1 - 0.32 11.3 27.2 0.77 10.1 7.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) HemX PF04375.9 KEG05128.1 - 0.34 9.4 21.8 0.031 12.8 5.6 2.0 1 1 1 2 2 2 0 HemX Phage_GPO PF05929.6 KEG05128.1 - 0.54 9.4 18.4 1.3 8.2 4.0 2.0 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF773 PF05600.7 KEG05128.1 - 0.57 8.8 17.7 0.16 10.7 4.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF773) ATG16 PF08614.6 KEG05128.1 - 0.62 9.8 29.7 0.79 9.5 10.3 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Mto2_bdg PF12808.2 KEG05128.1 - 0.65 10.1 45.7 0.33 11.0 3.5 5.9 1 1 3 5 5 5 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Phage_GP20 PF06810.6 KEG05128.1 - 0.66 9.3 31.1 0.75 9.2 6.3 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 IFT57 PF10498.4 KEG05128.1 - 0.76 8.4 18.7 1.1 7.9 13.0 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF812 PF05667.6 KEG05128.1 - 0.82 8.0 25.4 0.35 9.3 6.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) 4HB_MCP_1 PF12729.2 KEG05128.1 - 0.82 8.9 24.0 0.51 9.6 10.6 2.2 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction CDC37_N PF03234.9 KEG05128.1 - 0.87 9.8 20.0 0.97 9.7 13.8 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding ApoLp-III PF07464.6 KEG05128.1 - 0.93 9.4 24.6 0.63 10.0 5.2 2.3 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Cep57_CLD_2 PF14197.1 KEG05128.1 - 0.98 9.4 46.9 0.13 12.2 12.3 4.4 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 ERM PF00769.14 KEG05128.1 - 0.99 8.8 39.6 0.68 9.4 13.0 2.0 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Spc7 PF08317.6 KEG05128.1 - 1.2 7.6 25.1 1.5 7.4 17.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3322 PF11795.3 KEG05128.1 - 1.3 8.6 8.0 1.7 8.2 1.1 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) ZYG-11_interact PF05884.7 KEG05128.1 - 1.3 7.9 5.4 3.1 6.8 0.4 2.0 1 1 1 2 2 2 0 Interactor of ZYG-11 DivIVA PF05103.8 KEG05128.1 - 1.5 8.8 29.7 1.2 9.1 6.8 2.5 1 1 1 2 2 2 0 DivIVA protein APG6 PF04111.7 KEG05128.1 - 1.7 7.6 40.0 0.69 8.8 13.7 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Syntaxin PF00804.20 KEG05128.1 - 1.7 8.8 21.1 0.89 9.7 4.7 2.1 1 1 1 2 2 2 0 Syntaxin DUF1875 PF08961.5 KEG05128.1 - 1.8 7.8 25.3 6.2 6.0 3.8 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF1875) ADIP PF11559.3 KEG05128.1 - 2.3 8.1 29.3 2.4 8.0 6.6 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding BLOC1_2 PF10046.4 KEG05128.1 - 2.5 8.3 20.3 6.1 7.0 4.2 2.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 YjcZ PF13990.1 KEG05128.1 - 2.5 7.1 9.0 4.5 6.3 6.2 1.4 1 1 0 1 1 1 0 YjcZ-like protein PilJ PF13675.1 KEG05128.1 - 3 8.1 9.1 14 6.0 6.3 1.9 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF3450 PF11932.3 KEG05128.1 - 3.1 6.9 21.3 2.8 7.1 4.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF342 PF03961.8 KEG05128.1 - 3.2 6.0 21.5 7.8 4.7 14.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF342) HAUS6_N PF14661.1 KEG05128.1 - 3.2 7.0 23.3 19 4.5 16.1 1.9 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus V-ATPase_C PF03223.10 KEG05128.1 - 3.8 6.3 8.7 1.2 8.0 0.5 2.0 1 1 1 2 2 2 0 V-ATPase subunit C LOH1CR12 PF10158.4 KEG05128.1 - 3.8 7.3 7.3 15 5.3 4.3 2.0 1 1 0 1 1 1 0 Tumour suppressor protein Fzo_mitofusin PF04799.8 KEG05128.1 - 4.1 6.7 7.5 1.4 8.2 3.0 1.8 1 1 1 2 2 2 0 fzo-like conserved region DUF387 PF04079.11 KEG05128.1 - 4.2 6.7 8.7 5.4 6.3 5.0 2.0 1 1 1 2 2 2 0 Putative transcriptional regulators (Ypuh-like) Seryl_tRNA_N PF02403.17 KEG05128.1 - 4.5 7.3 28.7 6.1 6.8 11.7 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HAUS-augmin3 PF14932.1 KEG05128.1 - 4.8 6.2 27.7 14 4.7 19.2 1.7 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF2383 PF09537.5 KEG05128.1 - 5 7.4 19.8 2.8 8.2 1.9 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF2383) TelA PF05816.6 KEG05128.1 - 5.3 5.6 23.6 0.87 8.2 4.9 2.0 1 1 1 2 2 2 0 Toxic anion resistance protein (TelA) IncA PF04156.9 KEG05128.1 - 5.7 6.4 36.3 3.5e+02 0.6 25.1 2.0 1 1 0 1 1 1 0 IncA protein Aida_N PF08910.5 KEG05128.1 - 6 7.1 7.9 1.8 8.8 2.0 2.2 1 1 1 2 2 2 0 Aida N-terminus DUF501 PF04417.7 KEG05128.1 - 6.2 6.6 16.4 0.88 9.4 4.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF501) Atg14 PF10186.4 KEG05128.1 - 6.2 5.6 21.9 11 4.8 15.2 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Exonuc_VII_L PF02601.10 KEG05128.1 - 6.9 5.7 15.2 7.9 5.5 10.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2317 PF10079.4 KEG05128.1 - 7.7 4.9 17.5 9.4 4.7 12.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Salp15 PF12115.3 KEG05128.1 - 8.3 6.6 9.3 3.2 8.0 2.6 2.4 1 1 1 2 2 2 0 Salivary protein of 15kDa inhibits CD4+ T cell activation Cluap1 PF10234.4 KEG05128.1 - 8.7 5.4 22.4 3.6 6.7 4.7 2.1 1 1 1 2 2 2 0 Clusterin-associated protein-1 Mucin PF01456.12 KEG05130.1 - 1.7e-07 31.1 5.8 1.9e-07 30.9 4.0 1.1 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF2668 PF10873.3 KEG05134.1 - 1.5 8.9 6.0 2.7 8.1 4.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2668) TPR_2 PF07719.12 KEG05135.1 - 0.08 12.8 1.9 0.08 12.8 1.3 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat LEA_4 PF02987.11 KEG05135.1 - 0.22 11.4 15.9 0.21 11.4 1.0 3.4 3 0 0 3 3 3 0 Late embryogenesis abundant protein DUF3359 PF11839.3 KEG05135.1 - 0.31 11.4 29.4 0.98 9.8 4.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3359) TPR_4 PF07721.9 KEG05135.1 - 6.4 7.5 0.0 6.4 7.5 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF4398 PF14346.1 KEG05135.1 - 6.6 6.8 28.6 24 5.0 19.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4398) PTS_IIA PF02255.11 KEG05135.1 - 7.8 6.4 11.6 0.17 11.7 1.9 2.3 1 1 1 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit LRR_4 PF12799.2 KEG05138.1 - 3.3e-09 36.1 0.0 1.6e-05 24.3 0.0 3.3 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG05138.1 - 8.3e-06 25.4 0.0 0.00022 20.8 0.0 2.5 3 0 0 3 3 3 1 Leucine rich repeat LRR_6 PF13516.1 KEG05138.1 - 0.0012 18.6 0.0 0.021 14.8 0.0 2.8 3 0 0 3 3 3 1 Leucine Rich repeat LRR_1 PF00560.28 KEG05138.1 - 0.0021 17.8 0.1 16 6.0 0.0 3.5 3 0 0 3 3 3 1 Leucine Rich Repeat Ribosomal_L19e PF01280.15 KEG05139.1 - 0.024 14.4 2.1 0.029 14.1 1.5 1.1 1 0 0 1 1 1 0 Ribosomal protein L19e LRRNT_2 PF08263.7 KEG05139.1 - 0.029 14.3 2.0 0.05 13.5 1.4 1.3 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain Cep57_CLD_2 PF14197.1 KEG05140.1 - 1.7e-09 37.4 28.9 0.031 14.2 1.7 4.2 1 1 3 4 4 4 4 Centrosome localisation domain of PPC89 Mto2_bdg PF12808.2 KEG05140.1 - 4.5e-06 26.6 19.3 0.58 10.2 0.2 4.3 4 0 0 4 4 4 3 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF837 PF05769.6 KEG05140.1 - 6.9e-06 25.7 13.6 0.54 9.7 0.1 4.0 4 0 0 4 4 4 2 Protein of unknown function (DUF837) DUF4201 PF13870.1 KEG05140.1 - 2.2e-05 23.9 21.2 0.0003 20.2 3.6 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4201) Lebercilin PF15619.1 KEG05140.1 - 6.5e-05 22.4 19.4 0.0023 17.3 12.9 2.8 1 1 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease Sirohm_synth_C PF14823.1 KEG05140.1 - 0.00012 21.3 2.3 16 4.8 0.0 4.1 4 0 0 4 4 4 0 Sirohaem biosynthesis protein C-terminal IncA PF04156.9 KEG05140.1 - 0.00014 21.5 22.4 0.0076 15.8 5.9 2.0 1 1 1 2 2 2 2 IncA protein Rootletin PF15035.1 KEG05140.1 - 0.00024 21.1 18.5 0.12 12.2 4.6 2.8 1 1 2 3 3 3 3 Ciliary rootlet component, centrosome cohesion DivIC PF04977.10 KEG05140.1 - 0.00025 20.4 21.6 0.72 9.3 0.6 4.1 4 0 0 4 4 4 3 Septum formation initiator WEMBL PF05701.6 KEG05140.1 - 0.0014 17.1 19.6 0.0023 16.4 13.6 1.3 1 1 0 1 1 1 1 Weak chloroplast movement under blue light DUF848 PF05852.6 KEG05140.1 - 0.0016 18.2 11.0 0.021 14.6 2.8 2.1 1 1 1 2 2 2 2 Gammaherpesvirus protein of unknown function (DUF848) Rab5-bind PF09311.6 KEG05140.1 - 0.0022 17.9 23.7 0.18 11.7 5.9 2.9 1 1 0 2 2 2 2 Rabaptin-like protein Seryl_tRNA_N PF02403.17 KEG05140.1 - 0.004 17.1 16.2 0.17 11.8 0.8 3.3 1 1 2 3 3 3 2 Seryl-tRNA synthetase N-terminal domain PhoU PF01895.14 KEG05140.1 - 0.0045 17.4 10.0 0.75 10.2 0.5 3.1 1 1 2 3 3 3 1 PhoU domain DUF1542 PF07564.6 KEG05140.1 - 0.0067 16.4 15.4 0.37 10.8 0.5 3.4 3 1 0 3 3 3 1 Domain of Unknown Function (DUF1542) DUF3584 PF12128.3 KEG05140.1 - 0.0086 13.4 21.1 0.023 12.0 14.6 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3584) DUF869 PF05911.6 KEG05140.1 - 0.0094 14.2 15.6 0.037 12.2 3.8 2.0 1 1 1 2 2 2 2 Plant protein of unknown function (DUF869) GAS PF13851.1 KEG05140.1 - 0.0098 15.1 14.7 0.037 13.2 10.1 1.8 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding HOOK PF05622.7 KEG05140.1 - 0.012 13.4 20.6 0.024 12.4 14.3 1.5 1 1 0 1 1 1 0 HOOK protein bZIP_2 PF07716.10 KEG05140.1 - 0.014 15.1 26.4 1.1 9.1 0.5 4.2 3 1 1 4 4 4 0 Basic region leucine zipper Spc7 PF08317.6 KEG05140.1 - 0.014 14.0 11.6 0.02 13.5 8.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein FlaC_arch PF05377.6 KEG05140.1 - 0.017 15.0 3.6 51 3.8 0.0 3.9 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Metalloenzyme PF01676.13 KEG05140.1 - 0.02 14.2 1.2 20 4.4 0.0 3.0 3 0 0 3 3 3 0 Metalloenzyme superfamily IFT57 PF10498.4 KEG05140.1 - 0.022 13.4 9.1 0.47 9.1 2.3 2.0 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF4404 PF14357.1 KEG05140.1 - 0.029 14.7 20.3 0.92 9.9 4.0 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4404) TMPIT PF07851.8 KEG05140.1 - 0.034 13.2 3.0 0.024 13.7 0.8 1.4 1 1 1 2 2 2 0 TMPIT-like protein ATG16 PF08614.6 KEG05140.1 - 0.035 13.9 18.7 0.78 9.5 2.5 2.5 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) BLOC1_2 PF10046.4 KEG05140.1 - 0.038 14.1 8.0 2.4 8.3 0.5 3.1 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF972 PF06156.8 KEG05140.1 - 0.04 14.2 15.4 3.5 8.0 2.0 3.8 1 1 3 4 4 4 0 Protein of unknown function (DUF972) Catalase-rel PF06628.7 KEG05140.1 - 0.043 13.6 2.8 31 4.5 0.0 3.3 3 0 0 3 3 3 0 Catalase-related immune-responsive CENP-H PF05837.7 KEG05140.1 - 0.15 12.2 11.1 1.2 9.2 1.6 2.9 1 1 1 2 2 2 0 Centromere protein H (CENP-H) APG6 PF04111.7 KEG05140.1 - 0.19 10.7 23.1 0.074 12.0 9.8 1.9 1 1 1 2 2 2 0 Autophagy protein Apg6 Kinesin-relat_1 PF12711.2 KEG05140.1 - 0.19 12.1 18.3 7 7.1 0.6 3.9 1 1 3 4 4 4 0 Kinesin motor HTH_Tnp_1_2 PF13022.1 KEG05140.1 - 0.2 11.4 10.6 0.87 9.3 1.6 2.3 1 1 2 3 3 3 0 Helix-turn-helix of insertion element transposase V-SNARE PF05008.10 KEG05140.1 - 0.2 11.8 23.4 2 8.6 3.0 3.2 1 1 2 3 3 3 0 Vesicle transport v-SNARE protein N-terminus YlqD PF11068.3 KEG05140.1 - 0.2 11.6 22.1 1.2 9.1 0.9 3.6 1 1 1 3 3 3 0 YlqD protein Cast PF10174.4 KEG05140.1 - 0.26 9.2 21.1 0.32 8.9 14.7 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone DUF4559 PF15112.1 KEG05140.1 - 0.29 10.2 7.4 0.57 9.2 5.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) Macoilin PF09726.4 KEG05140.1 - 0.33 9.2 12.2 0.7 8.0 1.6 2.0 1 1 1 2 2 2 0 Transmembrane protein TBPIP PF07106.8 KEG05140.1 - 0.33 10.4 12.0 1.5 8.3 1.9 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4200 PF13863.1 KEG05140.1 - 0.42 10.5 23.2 2 8.3 10.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Remorin_C PF03763.8 KEG05140.1 - 0.57 9.7 14.2 1.8 8.0 1.2 3.1 1 1 2 3 3 3 0 Remorin, C-terminal region Kinetocho_Slk19 PF12709.2 KEG05140.1 - 0.58 10.2 17.2 2.7 8.1 1.2 3.9 1 1 3 4 4 4 0 Central kinetochore-associated KLRAQ PF10205.4 KEG05140.1 - 0.59 10.2 16.4 2.1 8.4 4.8 2.0 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein DUF4140 PF13600.1 KEG05140.1 - 0.72 10.3 29.0 2.8 8.4 1.3 3.9 1 1 3 4 4 4 0 N-terminal domain of unknown function (DUF4140) Scaffolding_pro PF11418.3 KEG05140.1 - 0.78 10.0 10.3 31 4.9 0.9 3.7 1 1 2 3 3 3 0 Phi29 scaffolding protein DUF2388 PF09498.5 KEG05140.1 - 0.82 9.3 11.1 9 6.0 0.2 3.6 4 0 0 4 4 3 0 Protein of unknown function (DUF2388) rRNA_proc-arch PF13234.1 KEG05140.1 - 0.84 8.7 7.8 0.85 8.7 0.8 2.1 1 1 0 2 2 2 0 rRNA-processing arch domain TerB-N PF13208.1 KEG05140.1 - 0.85 9.0 4.1 7.4 5.9 2.9 2.5 1 1 0 1 1 1 0 TerB-N DUF812 PF05667.6 KEG05140.1 - 0.91 7.9 9.9 0.99 7.8 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) CENP-F_leu_zip PF10473.4 KEG05140.1 - 0.95 9.3 22.7 13 5.6 13.9 2.2 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FimP PF09766.4 KEG05140.1 - 0.96 8.4 8.3 9.6 5.1 1.3 2.7 1 1 2 3 3 3 0 Fms-interacting protein Mod_r PF07200.8 KEG05140.1 - 0.98 9.3 14.8 6 6.7 6.3 2.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein AHSP PF09236.5 KEG05140.1 - 0.99 9.6 10.9 17 5.7 0.3 3.4 1 1 2 3 3 3 0 Alpha-haemoglobin stabilising protein FadA PF09403.5 KEG05140.1 - 1 9.3 21.1 2.8 7.9 5.4 2.1 1 1 1 2 2 2 0 Adhesion protein FadA KxDL PF10241.4 KEG05140.1 - 1.1 9.2 9.0 4.8 7.1 1.0 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein Herpes_BLRF2 PF05812.7 KEG05140.1 - 1.2 8.9 21.3 6.7 6.5 0.6 4.1 1 1 3 4 4 4 0 Herpesvirus BLRF2 protein TPR_MLP1_2 PF07926.7 KEG05140.1 - 1.2 8.9 20.2 25 4.6 13.8 2.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein FlgN PF05130.7 KEG05140.1 - 1.4 9.2 24.4 0.39 10.9 6.6 2.4 1 1 1 2 2 2 0 FlgN protein HrpB7 PF09486.5 KEG05140.1 - 1.5 8.7 19.1 9.8 6.0 13.2 2.5 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Sas10_Utp3 PF04000.10 KEG05140.1 - 1.8 8.8 12.0 23 5.2 2.4 3.6 2 1 1 3 3 3 0 Sas10/Utp3/C1D family DELLA PF12041.3 KEG05140.1 - 2.1 8.0 7.3 12 5.6 0.2 3.1 1 1 2 3 3 3 0 Transcriptional regulator DELLA protein N terminal NYD-SP28_assoc PF14775.1 KEG05140.1 - 2.2 8.0 14.4 23 4.8 0.1 4.4 4 1 0 4 4 4 0 Sperm tail C-terminal domain DUF3450 PF11932.3 KEG05140.1 - 2.3 7.4 12.6 4.1 6.5 5.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF724 PF05266.9 KEG05140.1 - 2.5 7.6 10.9 1.7 8.1 2.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Spectrin PF00435.16 KEG05140.1 - 2.5 8.4 17.9 1.2 9.4 4.5 2.5 1 1 1 2 2 2 0 Spectrin repeat AATF-Che1 PF13339.1 KEG05140.1 - 4.4 7.4 9.9 4.5e+02 0.9 6.8 2.6 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF4375 PF14300.1 KEG05140.1 - 4.8 7.1 11.1 21 5.1 2.1 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4375) Atg14 PF10186.4 KEG05140.1 - 5.2 5.9 13.7 9 5.1 9.5 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Nup54 PF13874.1 KEG05140.1 - 5.8 6.5 11.3 18 4.9 1.5 2.5 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 CorA PF01544.13 KEG05140.1 - 6.9 5.6 6.9 8.1 5.3 4.3 1.6 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein FUSC PF04632.7 KEG05140.1 - 7.1 4.9 10.6 8.4 4.6 7.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Cluap1 PF10234.4 KEG05140.1 - 7.6 5.6 11.4 9.6 5.3 1.9 2.5 1 1 0 2 2 2 0 Clusterin-associated protein-1 HALZ PF02183.13 KEG05140.1 - 8 6.2 19.2 17 5.2 0.3 4.4 4 1 0 4 4 4 0 Homeobox associated leucine zipper AAA_13 PF13166.1 KEG05140.1 - 8.3 4.7 10.2 13 4.0 7.1 1.4 1 1 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 KEG05140.1 - 8.5 4.0 7.1 10 3.8 4.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Psb28 PF03912.9 KEG05141.1 - 0.039 13.9 1.0 0.053 13.4 0.7 1.1 1 0 0 1 1 1 0 Psb28 protein EB_dh PF09459.5 KEG05143.1 - 0.074 12.4 0.0 0.084 12.3 0.0 1.1 1 0 0 1 1 1 0 Ethylbenzene dehydrogenase IFT57 PF10498.4 KEG05145.1 - 6.4e-06 25.1 9.2 0.00084 18.1 2.1 2.0 1 1 1 2 2 2 2 Intra-flagellar transport protein 57 CK2S PF15011.1 KEG05145.1 - 0.0076 16.0 5.6 0.048 13.4 3.1 2.0 1 1 1 2 2 2 2 Casein Kinase 2 substrate E2R135 PF11570.3 KEG05145.1 - 0.0092 16.0 4.7 0.59 10.2 0.4 2.2 1 1 1 2 2 2 2 Coiled-coil receptor-binding R-domain of colicin E2 DMPK_coil PF08826.5 KEG05145.1 - 0.027 14.3 23.2 0.22 11.4 6.8 3.1 2 1 0 2 2 2 0 DMPK coiled coil domain like HAUS2 PF15003.1 KEG05145.1 - 0.041 12.9 6.3 0.19 10.7 3.4 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 2 Blo-t-5 PF11642.3 KEG05145.1 - 0.041 13.6 5.3 0.49 10.1 1.7 2.3 1 1 1 2 2 2 0 Mite allergen Blo t 5 TFIIS_C PF01096.13 KEG05145.1 - 0.046 13.3 3.4 3.2 7.4 0.1 2.7 3 0 0 3 3 2 0 Transcription factor S-II (TFIIS) PEP-utilisers_N PF05524.8 KEG05145.1 - 0.047 13.4 9.8 0.074 12.8 6.4 1.6 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal Phage_mat-A PF03863.8 KEG05145.1 - 0.15 11.1 2.0 0.79 8.7 0.1 2.0 1 1 0 2 2 2 0 Phage maturation protein DUF2357 PF09823.4 KEG05145.1 - 0.19 10.8 3.8 0.28 10.2 2.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF2357) XhlA PF10779.4 KEG05145.1 - 0.25 11.2 12.2 0.73 9.7 1.3 2.3 2 0 0 2 2 2 0 Haemolysin XhlA Alpha-mann_mid PF09261.6 KEG05145.1 - 0.53 10.5 7.3 1.9 8.7 0.5 2.4 1 1 1 2 2 2 0 Alpha mannosidase, middle domain TMCO5 PF14992.1 KEG05145.1 - 0.85 8.6 16.1 1 8.3 11.1 1.1 1 0 0 1 1 1 0 TMCO5 family Cob_adeno_trans PF01923.13 KEG05145.1 - 0.93 9.2 7.6 1.2 8.8 4.4 1.7 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Prefoldin PF02996.12 KEG05145.1 - 1.1 8.9 13.1 1.6 8.4 1.1 2.5 2 1 0 2 2 2 0 Prefoldin subunit MobC PF05713.6 KEG05145.1 - 2 8.4 11.4 4.4 7.3 1.1 3.0 3 0 0 3 3 2 0 Bacterial mobilisation protein (MobC) Fmp27_WPPW PF10359.4 KEG05145.1 - 2.1 6.6 10.5 2.2 6.5 7.3 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF2564 PF10819.3 KEG05145.1 - 2.8 8.1 14.9 2.2 8.4 2.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2564) DUF641 PF04859.7 KEG05145.1 - 2.8 7.6 11.4 2.6 7.8 5.7 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Birna_RdRp PF04197.7 KEG05145.1 - 4.5 5.1 6.5 20 3.0 4.3 1.8 1 1 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) Tropomyosin_1 PF12718.2 KEG05145.1 - 7.1 6.4 24.0 69 3.2 16.7 1.9 1 1 0 1 1 1 0 Tropomyosin like Sec2p PF06428.6 KEG05145.1 - 9.2 6.1 18.6 1.9 8.3 3.0 2.4 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p FeoB_C PF07664.7 KEG05146.1 - 4.2e-06 26.0 0.0 2.2 7.7 0.0 3.8 3 1 1 4 4 4 3 Ferrous iron transport protein B C terminus Peptidase_M8 PF01457.11 KEG05147.1 - 3.1e-27 95.1 1.8 3.2e-27 95.0 1.3 1.0 1 0 0 1 1 1 1 Leishmanolysin MTH865 PF07747.6 KEG05148.1 - 0.015 14.9 2.9 10 5.8 0.0 3.6 2 2 2 4 4 4 0 MTH865-like family Cupin_1 PF00190.17 KEG05148.1 - 0.52 9.7 3.7 24 4.3 0.1 3.2 3 1 1 4 4 4 0 Cupin DUF2749 PF10907.3 KEG05148.1 - 0.67 9.8 21.7 4.3 7.2 0.2 4.4 2 2 3 5 5 5 0 Protein of unknown function (DUF2749) Guanylate_cyc PF00211.15 KEG05151.1 - 1.5e-08 34.2 0.0 1.9e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF3560 PF12083.3 KEG05152.1 - 7.6 6.5 11.0 0.26 11.3 3.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3560) Endonuclease_7 PF02945.10 KEG05153.1 - 0.29 10.8 3.0 0.35 10.6 1.4 1.6 1 1 0 1 1 1 0 Recombination endonuclease VII HTH_27 PF13463.1 KEG05158.1 - 0.04 14.2 0.1 3.2 8.1 0.1 2.3 1 1 1 2 2 2 0 Winged helix DNA-binding domain Ribosomal_L22 PF00237.14 KEG05158.1 - 0.086 12.7 0.2 0.17 11.8 0.1 1.6 1 1 0 1 1 1 0 Ribosomal protein L22p/L17e DFF-C PF09033.5 KEG05158.1 - 0.13 12.0 3.8 0.16 11.8 2.6 1.2 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain IncA PF04156.9 KEG05158.1 - 0.51 9.9 5.9 0.58 9.7 4.1 1.1 1 0 0 1 1 1 0 IncA protein Histone_HNS PF00816.16 KEG05158.1 - 0.77 10.2 8.6 0.66 10.5 0.8 2.2 1 1 1 2 2 2 0 H-NS histone family APG6 PF04111.7 KEG05158.1 - 2.4 7.1 6.2 2.7 6.9 4.3 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 FUSC PF04632.7 KEG05158.1 - 3.6 5.8 5.2 3.9 5.7 3.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3516 PF12029.3 KEG05161.1 - 0.064 12.0 0.3 0.082 11.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) Galactosyl_T PF01762.16 KEG05162.1 - 1.7e-05 24.5 0.1 0.072 12.6 0.0 2.8 1 1 1 3 3 3 2 Galactosyltransferase PEX11 PF05648.9 KEG05162.1 - 0.066 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) Ureide_permease PF07168.6 KEG05163.1 - 0.017 13.7 0.7 0.021 13.5 0.5 1.1 1 0 0 1 1 1 0 Ureide permease DUF1616 PF07760.6 KEG05163.1 - 0.46 9.5 2.7 0.32 10.0 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1616) Sugar_tr PF00083.19 KEG05164.1 - 3.1e-14 52.3 0.5 3.2e-14 52.3 0.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEG05164.1 - 0.0003 19.6 5.3 0.00037 19.3 3.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily PSI PF01437.20 KEG05164.1 - 0.036 14.2 11.2 0.79 9.9 1.5 2.2 1 1 1 2 2 2 0 Plexin repeat BT1 PF03092.11 KEG05164.1 - 0.066 11.9 1.3 0.087 11.5 0.9 1.1 1 0 0 1 1 1 0 BT1 family Paramecium_SA PF01508.11 KEG05164.1 - 0.22 11.7 13.4 4.9 7.4 9.3 2.3 1 1 0 1 1 1 0 Paramecium surface antigen domain Mucin PF01456.12 KEG05165.1 - 0.00054 19.7 22.6 0.00087 19.0 15.6 1.4 1 1 0 1 1 1 1 Mucin-like glycoprotein Inhibitor_I68 PF10468.4 KEG05165.1 - 0.069 13.3 0.2 0.069 13.3 0.1 1.8 1 1 0 1 1 1 0 Carboxypeptidase inhibitor I68 MerB PF03243.10 KEG05165.1 - 0.67 9.8 3.7 0.69 9.7 2.0 1.5 1 1 1 2 2 2 0 Alkylmercury lyase NPL4 PF05021.10 KEG05166.1 - 7.2e-06 25.3 0.0 7.4e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 NPL4 family Nodulin-like PF06813.8 KEG05172.1 - 2.8e-09 36.5 5.9 3e-09 36.5 4.1 1.0 1 0 0 1 1 1 1 Nodulin-like Golgin_A5 PF09787.4 KEG05173.1 - 0.018 13.5 7.7 0.023 13.2 5.3 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 CDC27 PF09507.5 KEG05173.1 - 0.08 12.1 16.0 0.1 11.8 11.1 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 FH2 PF02181.18 KEG05173.1 - 0.13 11.1 6.1 0.038 12.8 1.8 1.7 1 1 0 1 1 1 0 Formin Homology 2 Domain DUF2031 PF09592.5 KEG05173.1 - 0.3 10.1 2.6 0.41 9.7 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) Rabaptin PF03528.10 KEG05173.1 - 0.6 10.0 10.8 0.13 12.2 2.8 2.2 1 1 1 2 2 2 0 Rabaptin RE_Alw26IDE PF09665.5 KEG05173.1 - 1.1 7.8 4.0 1.1 7.8 2.8 1.2 1 0 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) HsbA PF12296.3 KEG05173.1 - 1.2 9.0 8.8 2.4 8.0 1.8 2.7 2 1 0 2 2 2 0 Hydrophobic surface binding protein A DUF4200 PF13863.1 KEG05173.1 - 1.8 8.5 14.9 0.41 10.5 4.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Seryl_tRNA_N PF02403.17 KEG05173.1 - 3.6 7.6 17.1 4 7.5 7.1 2.4 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 KEG05173.1 - 4.7 6.7 10.6 89 2.5 7.3 2.0 1 1 0 1 1 1 0 IncA protein DUF972 PF06156.8 KEG05173.1 - 6.7 7.1 9.7 1.5e+02 2.7 6.7 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF972) PALP PF00291.20 KEG05175.1 - 5.6e-07 29.0 0.0 6.5e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LacAB_rpiB PF02502.13 KEG05176.1 - 0.091 12.4 0.1 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribose/Galactose Isomerase FLYWCH PF04500.11 KEG05177.1 - 0.022 14.6 0.7 0.036 13.9 0.5 1.4 1 0 0 1 1 1 0 FLYWCH zinc finger domain XRN_N PF03159.13 KEG05178.1 - 0.0004 19.8 0.0 0.00052 19.4 0.0 1.1 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus LRR_4 PF12799.2 KEG05179.1 - 3.1e-17 61.7 0.0 0.001 18.6 0.0 4.1 1 1 5 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG05179.1 - 4.8e-10 39.0 0.1 0.0042 16.8 0.0 3.3 2 1 1 3 3 3 3 Leucine rich repeat LRR_6 PF13516.1 KEG05179.1 - 5.4e-07 29.0 1.4 0.51 10.5 0.0 4.9 4 1 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.28 KEG05179.1 - 7e-07 28.4 2.1 12 6.3 0.0 5.9 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_7 PF13504.1 KEG05179.1 - 0.0031 17.4 5.9 36 5.1 0.2 5.9 3 2 2 5 5 5 0 Leucine rich repeat GST_N_3 PF13417.1 KEG05179.1 - 0.049 13.8 0.0 3.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Methyltransf_13 PF08421.6 KEG05179.1 - 0.067 12.6 0.1 5.5 6.5 0.0 2.4 2 0 0 2 2 2 0 Putative zinc binding domain IncA PF04156.9 KEG05180.1 - 0.0053 16.3 0.1 0.0072 15.9 0.1 1.1 1 0 0 1 1 1 1 IncA protein TrbL PF04610.9 KEG05180.1 - 0.011 15.4 0.3 0.013 15.1 0.2 1.1 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein DUF1191 PF06697.7 KEG05180.1 - 0.026 13.3 0.1 0.032 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DAP10 PF07213.6 KEG05180.1 - 0.03 14.0 0.0 0.068 12.9 0.0 1.6 1 0 0 1 1 1 0 DAP10 membrane protein EphA2_TM PF14575.1 KEG05180.1 - 0.046 14.1 0.1 0.088 13.2 0.1 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain P12 PF12669.2 KEG05180.1 - 0.052 13.7 0.3 0.052 13.7 0.2 1.7 2 0 0 2 2 2 0 Virus attachment protein p12 family CD34_antigen PF06365.7 KEG05180.1 - 0.15 11.6 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family Peptidase_M8 PF01457.11 KEG05184.1 - 0.0011 17.4 0.0 0.0012 17.3 0.0 1.1 1 0 0 1 1 1 1 Leishmanolysin CDV3 PF15359.1 KEG05186.1 - 0.042 13.9 1.4 0.079 13.0 1.0 1.5 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 Peptidase_M8 PF01457.11 KEG05188.1 - 4.4e-41 140.8 1.5 4.8e-41 140.6 1.0 1.0 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.11 KEG05190.1 - 3.4e-31 108.1 2.7 3.7e-31 108.0 1.9 1.0 1 0 0 1 1 1 1 Leishmanolysin Penicil_amidase PF01804.13 KEG05191.1 - 4.8e-37 128.4 0.0 5.6e-37 128.2 0.0 1.0 1 0 0 1 1 1 1 Penicillin amidase Voltage_CLC PF00654.15 KEG05195.1 - 0.09 11.7 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 Voltage gated chloride channel BicD PF09730.4 KEG05198.1 - 0.0068 14.8 1.9 0.0068 14.8 1.3 1.7 2 0 0 2 2 2 1 Microtubule-associated protein Bicaudal-D ADIP PF11559.3 KEG05198.1 - 0.05 13.5 8.2 0.25 11.2 0.3 2.6 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Pox_A_type_inc PF04508.7 KEG05198.1 - 0.18 11.6 4.9 0.83 9.6 0.2 3.1 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat IncA PF04156.9 KEG05198.1 - 0.38 10.3 6.5 0.63 9.6 0.6 2.1 2 0 0 2 2 2 0 IncA protein TMF_TATA_bd PF12325.3 KEG05198.1 - 0.41 10.3 12.9 0.84 9.3 1.0 3.0 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.4 KEG05198.1 - 0.75 9.6 7.9 1.9 8.3 2.4 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.6 KEG05198.1 - 1.8 8.3 8.6 24 4.6 5.9 2.0 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Rab5-bind PF09311.6 KEG05198.1 - 2.3 8.0 11.9 8.2 6.2 1.3 3.0 3 0 0 3 3 3 0 Rabaptin-like protein FtsK_SpoIIIE PF01580.13 KEG05198.1 - 2.4 7.5 6.6 1.6 8.1 0.8 2.2 1 1 1 2 2 2 0 FtsK/SpoIIIE family Filament PF00038.16 KEG05198.1 - 2.6 7.4 9.5 0.19 11.1 1.7 1.9 2 0 0 2 2 2 0 Intermediate filament protein Bcr-Abl_Oligo PF09036.5 KEG05198.1 - 2.9 7.9 7.3 17 5.4 0.7 2.8 2 1 1 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain Tropomyosin_1 PF12718.2 KEG05198.1 - 3.1 7.6 8.7 1.9 8.3 1.5 2.2 2 0 0 2 2 2 0 Tropomyosin like RBD-FIP PF09457.5 KEG05198.1 - 3.1 7.6 10.0 0.41 10.4 1.0 2.8 3 0 0 3 3 3 0 FIP domain Peripla_BP_3 PF13377.1 KEG05198.1 - 5.7 6.9 11.7 7.9 6.4 0.6 2.5 1 1 1 2 2 2 0 Periplasmic binding protein-like domain Cortex-I_coil PF09304.5 KEG05198.1 - 9.7 6.2 10.4 7.2 6.6 0.6 2.3 2 0 0 2 2 2 0 Cortexillin I, coiled coil Mucin PF01456.12 KEG05199.1 - 0.0013 18.5 15.8 0.0023 17.6 10.9 1.5 1 1 0 1 1 1 1 Mucin-like glycoprotein Activator-TraM PF11657.3 KEG05199.1 - 0.057 12.8 4.1 0.1 12.0 2.9 1.5 1 0 0 1 1 1 0 Transcriptional activator TraM Imm5 PF14423.1 KEG05199.1 - 0.14 11.7 0.4 0.22 11.1 0.2 1.3 1 0 0 1 1 1 0 Immunity protein Imm5 DUF883 PF05957.8 KEG05199.1 - 0.18 12.2 8.8 1 9.8 3.5 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Macoilin PF09726.4 KEG05199.1 - 0.26 9.5 3.8 0.32 9.2 2.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Phasin_2 PF09361.5 KEG05199.1 - 0.36 10.8 8.0 0.93 9.5 2.8 2.2 1 1 1 2 2 2 0 Phasin protein Ribosomal_L22 PF00237.14 KEG05199.1 - 0.51 10.3 3.4 1.1 9.2 1.8 1.8 1 1 1 2 2 2 0 Ribosomal protein L22p/L17e ATP-synt_B PF00430.13 KEG05199.1 - 0.56 10.0 7.5 0.77 9.5 5.2 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) PTS_IIA PF02255.11 KEG05199.1 - 5.4 6.9 7.3 2.2 8.2 0.7 2.2 1 1 1 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit DUF1465 PF07323.7 KEG05201.1 - 4.5e-05 23.0 4.2 0.019 14.5 0.6 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1465) DUF2051 PF09738.4 KEG05201.1 - 0.0015 17.8 0.9 1 8.6 0.2 2.3 2 0 0 2 2 2 2 Double stranded RNA binding protein (DUF2051) bZIP_1 PF00170.16 KEG05201.1 - 0.0019 18.0 9.9 0.074 13.0 0.4 2.7 3 0 0 3 3 2 2 bZIP transcription factor UvsW PF11637.3 KEG05201.1 - 0.003 17.1 2.0 1.2 8.8 0.1 2.6 2 0 0 2 2 2 2 ATP-dependant DNA helicase UvsW CALCOCO1 PF07888.6 KEG05201.1 - 0.0067 14.7 8.1 0.19 9.9 3.4 2.0 2 0 0 2 2 2 2 Calcium binding and coiled-coil domain (CALCOCO1) like ATG16 PF08614.6 KEG05201.1 - 0.011 15.5 6.3 0.59 9.9 0.1 2.3 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) CtIP_N PF10482.4 KEG05201.1 - 0.011 15.4 9.7 0.46 10.2 3.9 3.0 2 1 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain HOOK PF05622.7 KEG05201.1 - 0.014 13.2 4.6 0.19 9.4 1.2 2.0 2 0 0 2 2 2 0 HOOK protein Hemerythrin PF01814.18 KEG05201.1 - 0.017 15.3 11.9 1 9.5 3.8 2.4 2 1 0 2 2 2 0 Hemerythrin HHE cation binding domain Cortex-I_coil PF09304.5 KEG05201.1 - 0.02 14.9 11.2 1.1 9.3 0.2 2.4 2 1 0 2 2 2 0 Cortexillin I, coiled coil Med21 PF11221.3 KEG05201.1 - 0.024 14.5 18.6 0.45 10.4 1.3 3.1 2 1 1 3 3 3 0 Subunit 21 of Mediator complex DUF972 PF06156.8 KEG05201.1 - 0.034 14.4 3.0 2.3 8.6 0.9 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Snapin_Pallidin PF14712.1 KEG05201.1 - 0.036 14.3 1.7 7.5 6.9 0.1 2.5 3 0 0 3 3 2 0 Snapin/Pallidin Vps23_core PF09454.5 KEG05201.1 - 0.036 13.6 1.3 7.6 6.2 0.0 2.6 3 0 0 3 3 2 0 Vps23 core domain Nnf1 PF03980.9 KEG05201.1 - 0.055 13.4 1.7 3 7.8 0.1 2.5 2 0 0 2 2 2 0 Nnf1 Cep57_MT_bd PF06657.8 KEG05201.1 - 0.062 13.2 6.9 2.3 8.2 0.1 3.4 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Myosin_tail_1 PF01576.14 KEG05201.1 - 0.064 10.9 17.5 0.31 8.6 7.8 2.2 2 0 0 2 2 2 0 Myosin tail DUF4472 PF14739.1 KEG05201.1 - 0.073 13.5 4.8 1.9 8.9 0.8 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4472) DUF4200 PF13863.1 KEG05201.1 - 0.076 12.9 7.7 2.2 8.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Spc24 PF08286.6 KEG05201.1 - 0.077 12.6 2.0 6.4 6.4 0.3 2.3 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 DivIC PF04977.10 KEG05201.1 - 0.082 12.4 7.2 2 7.9 0.4 2.3 2 0 0 2 2 2 0 Septum formation initiator Seryl_tRNA_N PF02403.17 KEG05201.1 - 0.1 12.6 4.1 4.2 7.4 0.0 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ADIP PF11559.3 KEG05201.1 - 0.11 12.3 7.0 0.91 9.4 1.3 2.4 3 0 0 3 3 2 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.4 KEG05201.1 - 0.17 11.7 16.8 4.1 7.2 7.2 2.9 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF848 PF05852.6 KEG05201.1 - 0.19 11.5 3.4 2.6 7.9 0.5 2.2 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) APG6 PF04111.7 KEG05201.1 - 0.22 10.5 7.3 3.3 6.6 0.1 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 Prefoldin PF02996.12 KEG05201.1 - 0.22 11.1 1.6 8.7 6.0 0.0 2.4 2 0 0 2 2 2 0 Prefoldin subunit MCC-bdg_PDZ PF10506.4 KEG05201.1 - 0.29 10.9 9.2 7.1 6.5 0.0 3.4 3 1 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Transcrip_act PF04949.8 KEG05201.1 - 0.29 10.7 5.9 4.4 6.9 0.4 2.5 2 1 0 2 2 2 0 Transcriptional activator Ax_dynein_light PF10211.4 KEG05201.1 - 0.31 10.8 7.1 3.2 7.5 2.0 2.2 2 0 0 2 2 2 0 Axonemal dynein light chain DUF4600 PF15372.1 KEG05201.1 - 0.34 11.1 2.2 4.4 7.5 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) BBS2_C PF14782.1 KEG05201.1 - 0.35 9.3 4.0 1.8 7.0 0.8 2.0 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal DUF904 PF06005.7 KEG05201.1 - 0.38 11.0 9.1 2.3 8.5 1.5 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF904) Flagellar_rod PF05149.7 KEG05201.1 - 0.4 9.8 6.3 0.33 10.0 1.5 2.0 2 0 0 2 2 2 0 Paraflagellar rod protein DUF2721 PF11026.3 KEG05201.1 - 0.42 10.2 5.5 6.1 6.4 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) PspB PF06667.7 KEG05201.1 - 0.47 10.4 5.9 8.1 6.4 0.4 2.3 2 0 0 2 2 2 0 Phage shock protein B M PF02370.11 KEG05201.1 - 0.62 10.5 24.9 12 6.6 0.2 5.9 5 1 1 6 6 6 0 M protein repeat WD40_alt PF14077.1 KEG05201.1 - 0.67 9.6 9.4 8 6.1 0.6 3.9 3 2 0 3 3 3 0 Alternative WD40 repeat motif Tropomyosin_1 PF12718.2 KEG05201.1 - 0.93 9.3 18.5 0.93 9.3 0.4 3.1 2 1 0 2 2 2 0 Tropomyosin like DUF4201 PF13870.1 KEG05201.1 - 1.2 8.5 4.1 9.6 5.5 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Mnd1 PF03962.10 KEG05201.1 - 1.6 8.3 7.3 5.6 6.5 2.6 2.1 2 0 0 2 2 2 0 Mnd1 family Prefoldin_2 PF01920.15 KEG05201.1 - 2 8.2 8.3 7 6.4 0.6 2.7 3 1 0 3 3 2 0 Prefoldin subunit IncA PF04156.9 KEG05201.1 - 3.4 7.2 13.6 1.7e+02 1.7 9.4 2.3 1 1 0 1 1 1 0 IncA protein MerR-DNA-bind PF09278.6 KEG05201.1 - 6.1 7.3 17.1 3.6 8.0 0.9 4.1 2 2 2 4 4 4 0 MerR, DNA binding DUF4164 PF13747.1 KEG05201.1 - 6.4 6.9 17.5 2.1 8.5 1.3 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) Methyltransf_31 PF13847.1 KEG05202.1 - 5.5e-06 26.0 0.0 5.8e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEG05202.1 - 3.5e-05 24.3 0.0 4.8e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEG05202.1 - 0.0039 17.6 0.0 0.0068 16.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 KEG05202.1 - 0.0056 16.0 0.0 0.0095 15.3 0.0 1.5 1 1 0 1 1 1 1 Nodulation protein S (NodS) Pox_MCEL PF03291.11 KEG05202.1 - 0.012 14.4 0.0 0.029 13.2 0.0 1.5 1 1 0 1 1 1 0 mRNA capping enzyme Methyltransf_12 PF08242.7 KEG05202.1 - 0.015 15.7 0.0 0.022 15.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_M8 PF01457.11 KEG05203.1 - 2.6e-29 101.9 0.0 2.8e-29 101.8 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin Peripla_BP_6 PF13458.1 KEG05204.1 - 6.1e-05 22.5 0.0 6.8e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein RVT_3 PF13456.1 KEG05206.1 - 0.23 11.2 2.8 32 4.3 0.1 3.1 3 0 0 3 3 3 0 Reverse transcriptase-like DinB PF05163.7 KEG05206.1 - 0.31 10.7 3.7 3.9 7.1 0.2 2.4 1 1 1 2 2 2 0 DinB family YlqD PF11068.3 KEG05206.1 - 0.41 10.7 5.4 7.8 6.5 0.4 2.2 2 0 0 2 2 2 0 YlqD protein HMG_box PF00505.14 KEG05206.1 - 0.74 10.1 4.0 4.3 7.6 0.3 2.5 2 0 0 2 2 2 0 HMG (high mobility group) box Muted PF14942.1 KEG05206.1 - 1 9.2 6.1 8.8 6.1 0.2 2.6 1 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein DUF2654 PF10849.3 KEG05206.1 - 1 9.1 5.4 52 3.6 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2654) FKBP_N PF01346.13 KEG05206.1 - 4.3 7.4 13.3 15 5.6 0.7 3.4 3 1 0 3 3 3 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase OmpH PF03938.9 KEG05206.1 - 6 6.7 14.4 45 3.9 9.3 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2533 PF10752.4 KEG05206.1 - 7.8 6.8 8.9 19 5.6 0.4 3.5 3 2 0 3 3 3 0 Protein of unknown function (DUF2533) PHP_C PF13263.1 KEG05206.1 - 8.4 5.9 10.7 32 4.1 0.2 3.2 3 0 0 3 3 3 0 PHP-associated Peptidase_M8 PF01457.11 KEG05212.1 - 3.4e-45 154.3 0.0 3.7e-45 154.2 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin ABC2_membrane_3 PF12698.2 KEG05213.1 - 1e-24 87.2 14.6 1.2e-24 87.0 10.1 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF70 PF01901.11 KEG05213.1 - 0.011 14.7 6.6 0.016 14.3 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF70 EamA PF00892.15 KEG05213.1 - 0.11 12.5 11.7 0.042 13.8 5.7 1.9 2 0 0 2 2 2 0 EamA-like transporter family DUF1129 PF06570.6 KEG05213.1 - 0.11 11.7 4.6 0.16 11.2 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) ABC2_membrane_4 PF12730.2 KEG05213.1 - 0.12 11.4 10.2 0.2 10.8 6.6 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein YqhR PF11085.3 KEG05213.1 - 0.18 11.3 3.9 0.12 11.9 1.6 1.5 1 1 0 1 1 1 0 Conserved membrane protein YqhR ABC2_membrane PF01061.19 KEG05213.1 - 0.26 10.4 11.5 0.6 9.2 8.0 1.6 1 1 0 1 1 1 0 ABC-2 type transporter DUF373 PF04123.8 KEG05213.1 - 0.27 10.2 7.4 0.32 9.9 5.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF373) YfhO PF09586.5 KEG05213.1 - 2.2 6.2 8.5 3.5 5.5 5.9 1.4 1 1 0 1 1 1 0 Bacterial membrane protein YfhO DUF3021 PF11457.3 KEG05213.1 - 2.9 7.7 9.6 0.57 10.0 2.5 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3021) Spot_14 PF07084.7 KEG05214.1 - 0.053 13.3 1.9 0.087 12.6 1.3 1.5 1 0 0 1 1 1 0 Thyroid hormone-inducible hepatic protein Spot 14 Mnd1 PF03962.10 KEG05216.1 - 0.044 13.4 2.1 0.048 13.3 1.5 1.1 1 0 0 1 1 1 0 Mnd1 family Laminin_I PF06008.9 KEG05216.1 - 0.096 11.9 6.1 0.12 11.6 4.3 1.1 1 0 0 1 1 1 0 Laminin Domain I Cut12 PF11500.3 KEG05216.1 - 0.19 11.4 4.3 0.25 11.0 3.0 1.1 1 0 0 1 1 1 0 Spindle pole body formation-associated protein ACCA PF03255.9 KEG05216.1 - 0.29 10.6 1.9 0.36 10.3 1.3 1.0 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit OmpH PF03938.9 KEG05216.1 - 5.4 6.9 9.5 6.6 6.6 6.6 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Abhydrolase_3 PF07859.8 KEG05219.1 - 6e-06 25.9 0.1 1.3e-05 24.8 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KEG05219.1 - 0.0061 16.4 0.3 0.012 15.4 0.1 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEG05219.1 - 0.058 13.1 0.0 0.16 11.6 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF4611 PF15387.1 KEG05219.1 - 0.14 12.3 2.0 0.21 11.7 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) SR-25 PF10500.4 KEG05222.1 - 8.3e-05 22.1 5.2 0.0001 21.8 3.6 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein BNIP3 PF06553.7 KEG05222.1 - 0.0089 15.4 5.5 0.011 15.0 3.8 1.1 1 0 0 1 1 1 1 BNIP3 Pox_Ag35 PF03286.9 KEG05222.1 - 0.0089 15.5 3.9 0.01 15.3 2.7 1.1 1 0 0 1 1 1 1 Pox virus Ag35 surface protein DUF3446 PF11928.3 KEG05222.1 - 0.03 14.4 4.2 0.052 13.7 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) DDHD PF02862.12 KEG05222.1 - 0.11 12.3 3.9 0.11 12.2 2.7 1.1 1 0 0 1 1 1 0 DDHD domain BORG_CEP PF14957.1 KEG05222.1 - 0.15 13.0 3.7 0.17 12.7 2.5 1.3 1 0 0 1 1 1 0 Cdc42 effector RR_TM4-6 PF06459.7 KEG05222.1 - 0.17 11.7 6.1 0.19 11.5 4.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FLO_LFY PF01698.11 KEG05222.1 - 0.2 10.4 3.5 0.21 10.3 2.4 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Herpes_DNAp_acc PF04929.7 KEG05222.1 - 0.2 10.5 4.9 0.24 10.3 3.4 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor PAT1 PF09770.4 KEG05222.1 - 0.23 9.6 11.0 0.24 9.6 7.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2360 PF10152.4 KEG05222.1 - 0.27 11.5 6.5 0.32 11.2 4.5 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) SelP_N PF04592.9 KEG05222.1 - 0.35 10.2 9.9 0.43 9.9 6.8 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF4106 PF13388.1 KEG05222.1 - 0.6 9.0 5.9 0.75 8.6 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) CDC45 PF02724.9 KEG05222.1 - 0.65 7.9 5.0 0.67 7.9 3.4 1.1 1 0 0 1 1 1 0 CDC45-like protein PBP_sp32 PF07222.7 KEG05222.1 - 1 8.5 8.7 1.2 8.2 6.0 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Hid1 PF12722.2 KEG05222.1 - 1.8 6.1 6.0 1.8 6.1 4.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CPSF73-100_C PF11718.3 KEG05222.1 - 1.8 7.8 5.2 2.5 7.3 3.6 1.2 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term DUF4175 PF13779.1 KEG05222.1 - 1.9 6.0 10.6 2.3 5.8 7.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Zip PF02535.17 KEG05222.1 - 2.5 7.0 9.5 2.9 6.8 6.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RIC3 PF15361.1 KEG05222.1 - 2.7 8.2 7.9 3.6 7.7 5.5 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 BAF1_ABF1 PF04684.8 KEG05222.1 - 3.3 6.4 13.9 4.1 6.1 9.7 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Gag_spuma PF03276.9 KEG05222.1 - 4 5.6 10.4 4.8 5.3 7.2 1.0 1 0 0 1 1 1 0 Spumavirus gag protein ELO PF01151.13 KEG05223.1 - 9.6e-30 103.6 8.3 1.1e-29 103.5 5.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Bestrophin PF01062.16 KEG05223.1 - 0.46 9.3 3.2 0.38 9.6 1.5 1.4 1 1 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel Chorion_2 PF03964.10 KEG05225.1 - 0.077 13.5 3.7 0.12 12.9 2.6 1.3 1 0 0 1 1 1 0 Chorion family 2 Hrs_helical PF12210.3 KEG05225.1 - 0.1 12.8 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate RRM_1 PF00076.17 KEG05227.1 - 1.4e-09 37.3 0.1 0.0017 17.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG05227.1 - 4.1e-07 29.8 0.3 1.7e-06 27.8 0.2 1.9 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG05227.1 - 2.8e-06 27.0 0.0 7e-06 25.8 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KEG05227.1 - 6.9e-06 25.7 0.5 2.1e-05 24.1 0.4 1.8 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif IncA PF04156.9 KEG05230.1 - 0.013 15.0 0.0 0.019 14.5 0.0 1.1 1 0 0 1 1 1 0 IncA protein S1FA PF04689.8 KEG05230.1 - 0.057 13.3 0.0 0.098 12.5 0.0 1.3 1 0 0 1 1 1 0 DNA binding protein S1FA TrbL PF04610.9 KEG05230.1 - 0.081 12.6 0.4 0.1 12.2 0.3 1.1 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein VSP PF03302.8 KEG05230.1 - 0.42 9.1 2.4 0.36 9.4 0.4 1.7 2 0 0 2 2 2 0 Giardia variant-specific surface protein TRAM_LAG1_CLN8 PF03798.11 KEG05231.1 - 7e-08 32.2 12.0 8.2e-08 32.0 8.3 1.1 1 0 0 1 1 1 1 TLC domain DUF2873 PF11395.3 KEG05231.1 - 0.038 13.5 4.4 0.038 13.5 3.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2873) MMPL PF03176.10 KEG05231.1 - 0.15 10.7 6.4 0.19 10.3 4.5 1.1 1 0 0 1 1 1 0 MMPL family G3P_acyltransf PF02660.10 KEG05231.1 - 0.48 9.9 7.8 0.66 9.5 5.4 1.2 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase Mucin PF01456.12 KEG05232.1 - 0.00029 20.6 19.7 0.00029 20.6 13.7 2.1 1 1 1 2 2 2 1 Mucin-like glycoprotein DUF3487 PF11990.3 KEG05234.1 - 0.14 11.5 2.4 0.19 11.1 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) DUF454 PF04304.8 KEG05234.1 - 0.24 11.4 1.6 0.47 10.5 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF454) DUF677 PF05055.7 KEG05234.1 - 5.9 5.4 6.2 6.2 5.3 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Mucin PF01456.12 KEG05236.1 - 0.055 13.2 0.1 0.068 12.9 0.0 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF2890 PF11081.3 KEG05236.1 - 3 7.8 9.6 3.5 7.6 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) PRT_C PF08372.5 KEG05238.1 - 0.31 10.5 1.4 0.28 10.7 0.1 1.4 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal DUF2457 PF10446.4 KEG05239.1 - 0.074 11.7 16.0 0.077 11.7 11.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Menin PF05053.8 KEG05239.1 - 0.082 11.0 2.4 0.093 10.8 1.7 1.0 1 0 0 1 1 1 0 Menin Daxx PF03344.10 KEG05239.1 - 0.54 8.6 9.9 0.59 8.5 6.8 1.1 1 0 0 1 1 1 0 Daxx Family ATG27 PF09451.5 KEG05239.1 - 0.76 8.9 6.6 1.3 8.2 4.6 1.4 1 0 0 1 1 1 0 Autophagy-related protein 27 DUF2722 PF10846.3 KEG05239.1 - 1.1 8.1 7.1 1.2 8.1 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CDC45 PF02724.9 KEG05239.1 - 1.4 6.8 7.1 1.4 6.9 4.9 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.5 KEG05239.1 - 3 6.8 9.3 3.2 6.7 6.5 1.2 1 0 0 1 1 1 0 BUD22 Upf2 PF04050.9 KEG05239.1 - 6.6 6.4 10.1 11 5.7 7.0 1.3 1 0 0 1 1 1 0 Up-frameshift suppressor 2 Packaging_FI PF14000.1 KEG05239.1 - 9 6.5 8.2 12 6.0 5.7 1.4 1 1 0 1 1 1 0 DNA packaging protein FI UPF0118 PF01594.11 KEG05240.1 - 0.011 14.7 0.1 0.011 14.7 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function DUF20 Got1 PF04178.7 KEG05241.1 - 2.9e-29 101.5 17.2 3.3e-29 101.3 11.9 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family Ank_3 PF13606.1 KEG05244.1 - 8e-05 22.5 0.7 2.2 8.7 0.0 3.5 3 1 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 KEG05244.1 - 0.00013 22.2 0.1 0.00087 19.5 0.1 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KEG05244.1 - 0.0044 16.7 3.2 11 6.0 0.1 3.9 3 1 1 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 KEG05244.1 - 0.046 13.9 0.9 5.9 7.2 0.1 2.7 2 1 0 2 2 2 0 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEG05244.1 - 0.069 13.6 0.0 2.6 8.6 0.0 2.8 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Amastin PF07344.6 KEG05247.1 - 1.3e-20 73.5 8.5 1.7e-20 73.2 5.9 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein PMP22_Claudin PF00822.15 KEG05247.1 - 0.00038 20.1 4.5 0.00054 19.6 3.1 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family DUF1345 PF07077.6 KEG05247.1 - 0.029 13.9 0.9 0.042 13.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) D-ser_dehydrat PF14031.1 KEG05247.1 - 0.05 13.7 0.5 6.3 7.0 0.1 2.8 3 0 0 3 3 3 0 Putative serine dehydratase domain DUF1616 PF07760.6 KEG05247.1 - 0.065 12.3 1.4 0.089 11.9 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) AzlD PF05437.7 KEG05247.1 - 0.4 10.6 5.5 0.3 11.0 0.4 2.4 3 0 0 3 3 3 0 Branched-chain amino acid transport protein (AzlD) MscS_TM PF12794.2 KEG05247.1 - 0.49 8.9 4.8 0.2 10.2 1.1 1.8 1 1 1 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Ninjurin PF04923.7 KEG05247.1 - 3.4 7.4 5.7 1.3 8.8 1.2 2.2 2 1 0 2 2 2 0 Ninjurin YibE_F PF07907.6 KEG05247.1 - 6.3 5.9 9.7 0.4 9.8 3.0 1.8 2 1 0 2 2 2 0 YibE/F-like protein Med25_SD1 PF11235.3 KEG05251.1 - 0.31 11.3 5.7 0.23 11.7 0.3 2.0 1 1 1 2 2 2 0 Mediator complex subunit 25 synapsin 1 EAL PF00563.15 KEG05255.1 - 0.063 12.7 0.1 0.083 12.3 0.1 1.2 1 0 0 1 1 1 0 EAL domain Amastin PF07344.6 KEG05257.1 - 4.3e-07 29.6 2.6 5.5e-07 29.3 1.7 1.3 1 1 0 1 1 1 1 Amastin surface glycoprotein HIG_1_N PF04588.8 KEG05257.1 - 0.038 13.7 1.7 2.4 7.9 0.1 2.5 2 0 0 2 2 2 0 Hypoxia induced protein conserved region SUR7 PF06687.7 KEG05257.1 - 0.052 13.1 2.3 0.075 12.5 0.3 1.8 2 0 0 2 2 2 0 SUR7/PalI family DUF1660 PF07874.6 KEG05260.1 - 1.3 9.3 3.8 13 6.1 0.4 2.3 1 1 1 2 2 2 0 Prophage protein (DUF1660) BMC PF00936.14 KEG05261.1 - 0.72 9.5 9.3 4.7 6.9 6.5 2.4 1 1 0 1 1 1 0 BMC domain Hid1 PF12722.2 KEG05261.1 - 7.2 4.1 8.1 7.9 4.0 5.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein EBP50_C-term PF09007.6 KEG05261.1 - 8.9 6.2 7.9 2.1 8.2 2.4 2.4 2 0 0 2 2 2 0 EBP50, C-terminal Guanylate_cyc PF00211.15 KEG05262.1 - 0.00098 18.5 0.0 0.0019 17.6 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Syndecan PF01034.15 KEG05262.1 - 0.0085 15.7 0.2 0.016 14.8 0.1 1.3 1 0 0 1 1 1 1 Syndecan domain DUF3481 PF11980.3 KEG05262.1 - 0.015 15.1 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) PrgI PF12666.2 KEG05262.1 - 0.055 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 PrgI family protein Peripla_BP_6 PF13458.1 KEG05262.1 - 0.059 12.7 0.1 0.074 12.3 0.1 1.1 1 0 0 1 1 1 0 Periplasmic binding protein Nitrate_red_gam PF02665.9 KEG05262.1 - 0.072 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Adeno_E3_CR2 PF02439.10 KEG05262.1 - 0.083 12.4 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Mucin PF01456.12 KEG05264.1 - 0.24 11.1 19.0 1.2 8.9 13.1 2.3 1 1 0 1 1 1 0 Mucin-like glycoprotein KMP11 PF03037.11 KEG05266.1 - 1e-56 189.4 17.5 1.1e-56 189.3 12.2 1.0 1 0 0 1 1 1 1 Kinetoplastid membrane protein 11 Apolipoprotein PF01442.13 KEG05266.1 - 0.007 15.8 3.5 0.02 14.3 2.4 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Lyase_8_N PF08124.6 KEG05266.1 - 0.017 14.0 2.1 0.017 13.9 1.5 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain AAA_32 PF13654.1 KEG05266.1 - 0.019 13.6 3.7 0.02 13.5 2.5 1.0 1 0 0 1 1 1 0 AAA domain FCH PF00611.18 KEG05266.1 - 0.023 14.8 5.8 0.031 14.4 2.2 2.0 1 1 1 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain Brr6_like_C_C PF10104.4 KEG05266.1 - 0.035 13.6 0.7 0.038 13.5 0.5 1.1 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain T5orf172 PF10544.4 KEG05266.1 - 0.068 13.5 1.9 0.08 13.3 1.3 1.2 1 0 0 1 1 1 0 T5orf172 domain TroA PF01297.12 KEG05266.1 - 0.07 12.3 2.0 2.7 7.1 0.1 2.0 1 1 1 2 2 2 0 Periplasmic solute binding protein family DUF3584 PF12128.3 KEG05266.1 - 0.073 10.4 4.1 0.084 10.1 2.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Metal_resist PF13801.1 KEG05266.1 - 0.078 12.9 0.8 0.94 9.4 0.0 2.0 1 1 1 2 2 2 0 Heavy-metal resistance Mating_N PF12731.2 KEG05266.1 - 0.094 12.5 1.2 0.15 11.9 0.8 1.4 1 1 0 1 1 1 0 Mating-type protein beta 1 Herpes_BLRF2 PF05812.7 KEG05266.1 - 0.14 12.0 3.6 0.17 11.6 2.5 1.2 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein FliD_C PF07195.7 KEG05266.1 - 0.23 10.7 4.2 0.42 9.8 2.9 1.5 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus YlqD PF11068.3 KEG05266.1 - 0.27 11.2 6.5 0.67 10.0 4.5 1.6 1 1 0 1 1 1 0 YlqD protein CBP4 PF07960.6 KEG05266.1 - 0.48 10.0 4.2 0.17 11.5 0.7 1.7 1 1 1 2 2 2 0 CBP4 DUF4404 PF14357.1 KEG05266.1 - 0.53 10.7 3.7 8.8 6.8 2.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) LKAAEAR PF15478.1 KEG05266.1 - 0.55 10.4 6.5 0.36 11.0 1.6 1.9 1 1 1 2 2 2 0 Family of unknown function with LKAAEAR motif Vps54 PF07928.7 KEG05266.1 - 0.6 10.2 3.7 0.4 10.8 1.1 1.7 2 0 0 2 2 2 0 Vps54-like protein DUF922 PF06037.6 KEG05266.1 - 0.66 9.2 4.3 0.48 9.7 1.8 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF922) ARL2_Bind_BART PF11527.3 KEG05266.1 - 0.73 9.6 9.8 1.1 9.0 6.7 1.5 1 1 0 1 1 1 0 The ARF-like 2 binding protein BART DUF2884 PF11101.3 KEG05266.1 - 0.77 9.0 8.2 2 7.7 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) DIOX_N PF14226.1 KEG05266.1 - 0.94 10.0 5.2 1.1 9.7 3.6 1.1 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal NYD-SP28 PF14772.1 KEG05266.1 - 0.99 9.5 8.0 6.1 6.9 0.2 2.4 2 1 0 2 2 2 0 Sperm tail DUF148 PF02520.12 KEG05266.1 - 1 9.1 7.6 9.7 6.0 3.1 2.2 1 1 1 2 2 2 0 Domain of unknown function DUF148 DUF3829 PF12889.2 KEG05266.1 - 2.6 7.1 10.8 4.8 6.2 7.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3829) YtxH PF12732.2 KEG05266.1 - 4.8 7.6 5.8 0.79 10.1 0.8 1.8 1 1 1 2 2 2 0 YtxH-like protein Mitofilin PF09731.4 KEG05266.1 - 5.6 5.4 10.1 6.5 5.2 7.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein TipAS PF07739.8 KEG05266.1 - 6.6 7.0 10.5 2.8 8.2 2.1 2.0 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain EcsB PF05975.7 KEG05267.1 - 0.029 12.8 5.6 0.032 12.7 3.9 1.0 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB DUF1700 PF08006.6 KEG05267.1 - 9 5.5 8.0 11 5.2 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) YlbD_coat PF14071.1 KEG05270.1 - 0.019 15.0 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative coat protein RecR PF02132.10 KEG05270.1 - 0.15 11.4 0.1 0.34 10.3 0.1 1.6 1 0 0 1 1 1 0 RecR protein Mucin PF01456.12 KEG05270.1 - 2.9 7.6 8.7 10 5.8 6.0 1.8 1 1 0 1 1 1 0 Mucin-like glycoprotein Gastrin PF00918.12 KEG05272.1 - 0.013 16.3 6.6 0.02 15.7 4.5 1.3 1 1 0 1 1 1 0 Gastrin/cholecystokinin family Nop25 PF09805.4 KEG05272.1 - 0.68 10.0 9.1 0.84 9.7 6.3 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF843 PF05814.6 KEG05274.1 - 0.041 13.6 0.0 4 7.3 0.0 2.2 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) ApoLp-III PF07464.6 KEG05279.1 - 0.003 17.5 10.2 0.017 15.1 6.1 2.1 1 1 1 2 2 2 1 Apolipophorin-III precursor (apoLp-III) XRCC4 PF06632.7 KEG05279.1 - 0.0077 15.1 1.3 0.01 14.7 0.9 1.4 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 HALZ PF02183.13 KEG05279.1 - 0.01 15.5 4.0 0.01 15.5 2.8 3.2 3 1 0 3 3 3 0 Homeobox associated leucine zipper Vps5 PF09325.5 KEG05279.1 - 0.018 14.3 6.5 0.021 14.0 4.5 1.1 1 0 0 1 1 1 0 Vps5 C terminal like Spc7 PF08317.6 KEG05279.1 - 0.019 13.6 9.3 0.025 13.2 6.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein HrpB7 PF09486.5 KEG05279.1 - 0.027 14.4 5.4 0.027 14.4 3.8 2.9 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) Leu_zip PF15294.1 KEG05279.1 - 0.044 12.8 10.6 0.081 12.0 7.3 1.4 1 1 0 1 1 1 0 Leucine zipper ATG16 PF08614.6 KEG05279.1 - 0.093 12.5 12.7 0.17 11.7 8.8 1.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) NPV_P10 PF05531.7 KEG05279.1 - 0.15 12.3 2.6 4.5 7.5 0.1 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF641 PF04859.7 KEG05279.1 - 0.18 11.5 11.4 0.12 12.1 4.3 2.3 1 1 0 2 2 2 0 Plant protein of unknown function (DUF641) ADIP PF11559.3 KEG05279.1 - 0.19 11.6 15.7 0.082 12.8 6.5 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding KIAA1430 PF13879.1 KEG05279.1 - 0.24 11.8 4.4 0.56 10.6 3.1 1.6 1 0 0 1 1 1 0 KIAA1430 homologue UPF0242 PF06785.6 KEG05279.1 - 0.24 10.0 9.7 0.022 13.4 3.5 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) IncA PF04156.9 KEG05279.1 - 0.27 10.8 18.5 4.2 6.9 12.8 2.0 1 1 0 1 1 1 0 IncA protein Snapin_Pallidin PF14712.1 KEG05279.1 - 0.34 11.2 8.4 0.52 10.6 1.4 2.4 1 1 1 2 2 2 0 Snapin/Pallidin DivIVA PF05103.8 KEG05279.1 - 0.47 10.4 17.7 0.47 10.5 9.1 2.1 2 0 0 2 2 2 0 DivIVA protein Atg14 PF10186.4 KEG05279.1 - 0.63 8.9 12.2 0.93 8.3 8.5 1.3 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DivIC PF04977.10 KEG05279.1 - 0.66 9.5 18.1 0.35 10.3 4.2 2.9 2 1 1 3 3 3 0 Septum formation initiator DUF972 PF06156.8 KEG05279.1 - 0.68 10.3 11.7 1.2 9.5 3.6 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF972) AAA_23 PF13476.1 KEG05279.1 - 0.99 9.6 4.2 1.2 9.4 2.9 1.2 1 0 0 1 1 1 0 AAA domain Filament PF00038.16 KEG05279.1 - 1.4 8.2 18.1 20 4.4 12.6 1.9 1 1 0 1 1 1 0 Intermediate filament protein HalX PF08663.5 KEG05279.1 - 2.1 8.3 9.6 0.19 11.7 0.7 3.1 2 2 2 4 4 4 0 HalX domain bZIP_1 PF00170.16 KEG05279.1 - 2.4 8.1 10.9 6.6 6.7 0.4 2.7 2 1 0 2 2 2 0 bZIP transcription factor TPR_MLP1_2 PF07926.7 KEG05279.1 - 3 7.5 17.6 58 3.4 8.6 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Kinetocho_Slk19 PF12709.2 KEG05279.1 - 4.4 7.4 10.4 1.1 9.3 2.0 2.9 2 2 1 3 3 3 0 Central kinetochore-associated TSC22 PF01166.13 KEG05279.1 - 6.9 6.7 10.0 11 6.0 2.2 3.5 2 2 2 4 4 4 0 TSC-22/dip/bun family NYD-SP28_assoc PF14775.1 KEG05279.1 - 7.5 6.3 7.5 0.66 9.7 1.0 2.3 2 1 0 2 2 2 0 Sperm tail C-terminal domain DUF904 PF06005.7 KEG05279.1 - 8.5 6.7 18.8 13 6.1 0.4 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF904) GrpE PF01025.14 KEG05279.1 - 9.5 5.7 13.9 1.3 8.4 3.6 2.1 1 1 1 2 2 2 0 GrpE DUF724 PF05266.9 KEG05279.1 - 9.6 5.7 11.3 27 4.2 7.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Mucin PF01456.12 KEG05280.1 - 0.00011 21.9 18.1 0.00011 21.9 12.6 2.5 1 1 0 2 2 2 1 Mucin-like glycoprotein MAPEG PF01124.13 KEG05282.1 - 0.043 13.4 0.0 0.2 11.2 0.0 2.0 2 1 0 2 2 2 0 MAPEG family P12 PF12669.2 KEG05282.1 - 0.046 13.9 0.1 0.066 13.4 0.1 1.2 1 0 0 1 1 1 0 Virus attachment protein p12 family DUF1191 PF06697.7 KEG05282.1 - 0.1 11.4 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) CaM_bdg_C0 PF10562.4 KEG05287.1 - 0.00044 20.0 2.9 0.69 9.8 0.1 3.4 3 0 0 3 3 3 3 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit Ycf9 PF01737.12 KEG05287.1 - 0.036 13.4 2.9 19 4.7 0.0 3.7 4 0 0 4 4 4 0 YCF9 Cortex-I_coil PF09304.5 KEG05290.1 - 4.3e-06 26.7 4.7 5.6e-06 26.3 3.2 1.1 1 0 0 1 1 1 1 Cortexillin I, coiled coil MAP65_ASE1 PF03999.7 KEG05290.1 - 0.00082 18.0 1.4 0.00092 17.9 1.0 1.0 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) DUF1664 PF07889.7 KEG05290.1 - 0.024 14.4 0.3 0.088 12.6 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.7 KEG05290.1 - 0.048 13.4 0.7 0.048 13.4 0.5 1.9 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 KEG05290.1 - 0.049 13.4 7.7 0.064 13.1 5.4 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4164 PF13747.1 KEG05290.1 - 0.072 13.2 4.8 3.9 7.6 1.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Prefoldin_2 PF01920.15 KEG05290.1 - 0.3 10.8 4.0 6.5 6.5 0.0 2.5 1 1 1 2 2 2 0 Prefoldin subunit BCAS2 PF05700.6 KEG05290.1 - 0.61 9.5 3.9 0.39 10.1 0.4 1.8 1 1 1 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) M PF02370.11 KEG05290.1 - 1.5 9.4 9.7 35 5.2 0.2 3.9 3 1 1 4 4 4 0 M protein repeat Poty_coat PF00767.13 KEG05291.1 - 0.019 14.2 0.1 0.025 13.8 0.1 1.1 1 0 0 1 1 1 0 Potyvirus coat protein Peripla_BP_6 PF13458.1 KEG05292.1 - 0.0011 18.3 0.0 0.0013 18.1 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein ESX-1_EspG PF14011.1 KEG05293.1 - 0.15 11.3 5.7 0.23 10.6 0.7 2.0 1 1 1 2 2 2 0 EspG family SecA_DEAD PF07517.9 KEG05296.1 - 0.13 11.5 3.4 0.089 12.0 0.5 1.8 1 1 0 2 2 2 0 SecA DEAD-like domain SLX9 PF15341.1 KEG05296.1 - 8.1 6.9 11.4 18 5.8 7.8 1.7 1 1 0 1 1 1 0 Ribosome biogenesis protein SLX9 Atg8 PF02991.11 KEG05297.1 - 4.5e-12 45.8 0.0 5e-12 45.7 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 KEG05297.1 - 0.02 15.1 0.0 0.021 14.9 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-like autophagy protein Apg12 SpoIIE PF07228.7 KEG05297.1 - 0.13 11.9 0.0 0.15 11.7 0.0 1.0 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) HTH_30 PF13556.1 KEG05298.1 - 0.036 13.6 0.0 0.093 12.3 0.0 1.8 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain zf-C3HC4_3 PF13920.1 KEG05299.1 - 2.6e-11 43.0 15.1 4e-11 42.4 10.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEG05299.1 - 4.7e-05 23.3 19.4 8.7e-05 22.4 13.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEG05299.1 - 0.0041 16.8 15.9 0.0084 15.8 11.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.1 KEG05299.1 - 1.1 8.8 12.0 4.2 7.0 8.4 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 P19Arf_N PF07392.7 KEG05301.1 - 0.14 12.3 0.1 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus DUF2556 PF10831.3 KEG05302.1 - 0.012 15.2 1.0 0.023 14.3 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2556) Innexin PF00876.13 KEG05302.1 - 0.084 11.9 3.6 0.091 11.8 2.5 1.2 1 0 0 1 1 1 0 Innexin Helicase_IV_N PF12462.3 KEG05303.1 - 0.015 14.9 0.4 0.019 14.6 0.3 1.1 1 0 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal Borrelia_P83 PF05262.6 KEG05307.1 - 4 5.6 45.9 4.9 5.3 31.8 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein PLRV_ORF5 PF01690.12 KEG05307.1 - 4.3 6.3 19.9 5.3 6.0 13.8 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF940 PF06082.6 KEG05307.1 - 6.6 5.1 12.2 8.5 4.7 8.5 1.2 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) MIP-T3 PF10243.4 KEG05307.1 - 7.9 4.8 55.8 10 4.4 38.7 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Mucin PF01456.12 KEG05310.1 - 0.19 11.4 21.0 5.5 6.7 14.4 2.3 1 1 0 1 1 1 0 Mucin-like glycoprotein SNARE PF05739.14 KEG05311.1 - 0.013 15.1 0.8 0.013 15.1 0.5 1.5 2 0 0 2 2 2 0 SNARE domain DUF3375 PF11855.3 KEG05311.1 - 0.014 14.1 0.6 0.023 13.4 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) DUF1772 PF08592.6 KEG05312.1 - 4.1 7.1 10.7 0.48 10.1 4.4 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) DUF418 PF04235.7 KEG05312.1 - 4.4 6.9 10.2 0.19 11.3 2.7 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF418) TPPK_C PF12555.3 KEG05312.1 - 9.1 6.0 8.4 0.9 9.3 0.8 2.7 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal DUF2101 PF09874.4 KEG05312.1 - 9.6 5.6 14.9 0.29 10.5 6.1 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) AAA PF00004.24 KEG05314.1 - 1e-05 25.7 0.0 0.011 15.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KEG05314.1 - 0.0004 20.0 0.7 0.0011 18.6 0.1 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 KEG05314.1 - 0.0021 18.1 0.3 0.016 15.3 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 KEG05314.1 - 0.0031 18.3 0.2 0.0093 16.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KEG05314.1 - 0.0055 16.1 2.8 0.074 12.4 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 KEG05314.1 - 0.0076 16.2 0.0 0.0076 16.2 0.0 3.1 2 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 KEG05314.1 - 0.014 15.1 0.1 0.052 13.2 0.1 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 KEG05314.1 - 0.021 15.1 0.0 0.049 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KEG05314.1 - 0.022 14.1 0.0 0.093 12.1 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein Troponin PF00992.15 KEG05314.1 - 0.023 14.7 1.7 0.034 14.1 1.2 1.2 1 0 0 1 1 1 0 Troponin Zeta_toxin PF06414.7 KEG05314.1 - 0.023 13.7 0.0 0.046 12.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 KEG05314.1 - 0.056 13.3 0.8 0.16 11.8 0.0 2.1 2 1 0 2 2 2 0 AAA domain cobW PF02492.14 KEG05314.1 - 0.076 12.4 0.1 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 KEG05314.1 - 0.1 12.5 0.0 0.1 12.5 0.0 2.5 2 1 0 3 3 3 0 AAA domain NACHT PF05729.7 KEG05314.1 - 0.1 12.2 1.1 1.1 8.9 0.0 2.6 3 0 0 3 3 3 0 NACHT domain DUF2075 PF09848.4 KEG05314.1 - 0.14 11.0 0.8 9.6 5.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Antistasin PF02822.9 KEG05315.1 - 0.16 12.2 0.3 0.3 11.4 0.2 1.4 1 0 0 1 1 1 0 Antistasin family Galactosyl_T PF01762.16 KEG05317.1 - 0.05 13.2 0.1 0.26 10.8 0.0 2.2 2 1 1 3 3 3 0 Galactosyltransferase Rhomboid PF01694.17 KEG05319.1 - 0.0028 17.6 1.3 0.0064 16.5 0.9 1.6 1 1 0 1 1 1 1 Rhomboid family RHSP PF07999.6 KEG05320.1 - 1.4e-41 142.5 0.3 1.8e-41 142.2 0.2 1.0 1 0 0 1 1 1 1 Retrotransposon hot spot protein DUF2113 PF09886.4 KEG05320.1 - 0.019 14.1 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2113) Opi1 PF08618.5 KEG05321.1 - 0.013 14.4 1.9 0.015 14.2 1.3 1.1 1 0 0 1 1 1 0 Transcription factor Opi1 MSA-2c PF12238.3 KEG05321.1 - 0.36 10.4 5.4 0.45 10.1 3.7 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c DUF605 PF04652.11 KEG05321.1 - 1.1 8.6 8.3 1.2 8.4 5.7 1.0 1 0 0 1 1 1 0 Vta1 like Histone PF00125.19 KEG05324.1 - 2.2e-11 43.6 0.1 2.8e-11 43.3 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KEG05324.1 - 0.013 15.5 0.2 0.04 13.9 0.0 1.8 1 1 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.10 KEG05324.1 - 0.026 14.3 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TAF PF02969.12 KEG05324.1 - 0.026 14.4 0.2 0.043 13.7 0.1 1.5 1 1 0 1 1 1 0 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.8 KEG05324.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated Peptidase_M8 PF01457.11 KEG05325.1 - 1.2e-83 281.2 0.1 1.4e-83 280.9 0.1 1.0 1 0 0 1 1 1 1 Leishmanolysin Mucin PF01456.12 KEG05326.1 - 3.7e-05 23.5 22.3 3.7e-05 23.5 15.4 2.4 2 1 0 2 2 2 2 Mucin-like glycoprotein Toxin_39 PF15500.1 KEG05326.1 - 0.053 13.6 2.2 0.76 9.9 0.1 2.6 2 0 0 2 2 2 0 Putative RNase-like toxin DUF2413 PF10310.4 KEG05326.1 - 0.7 8.6 14.3 0.98 8.1 9.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) IncA PF04156.9 KEG05327.1 - 0.0044 16.6 0.0 0.0055 16.3 0.0 1.2 1 0 0 1 1 1 1 IncA protein TrbL PF04610.9 KEG05327.1 - 0.031 13.9 0.5 0.046 13.4 0.3 1.2 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein EphA2_TM PF14575.1 KEG05327.1 - 0.043 14.2 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1191 PF06697.7 KEG05327.1 - 0.044 12.5 0.3 0.15 10.8 0.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1191) Sensor PF13796.1 KEG05327.1 - 0.06 12.9 0.1 0.095 12.3 0.1 1.3 1 0 0 1 1 1 0 Putative sensor VSP PF03302.8 KEG05327.1 - 0.18 10.3 4.6 0.42 9.1 3.3 1.5 1 1 1 2 2 2 0 Giardia variant-specific surface protein ETF PF01012.16 KEG05330.1 - 0.066 12.9 3.9 0.061 13.0 0.3 2.3 1 1 1 2 2 2 0 Electron transfer flavoprotein domain CytochromB561_N PF09786.4 KEG05334.1 - 0.13 10.7 2.4 0.14 10.6 1.7 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Mu-like_gpT PF10124.4 KEG05334.1 - 7.7 5.3 8.0 3.7 6.4 1.2 2.4 1 1 1 2 2 2 0 Mu-like prophage major head subunit gpT Phytase-like PF13449.1 KEG05336.1 - 0.1 11.8 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Esterase-like activity of phytase HRXXH PF13933.1 KEG05338.1 - 0.12 11.7 0.2 0.14 11.5 0.1 1.1 1 0 0 1 1 1 0 Putative peptidase family OGFr_III PF04680.8 KEG05339.1 - 0.0004 20.3 0.1 1.2 9.4 0.0 2.4 2 0 0 2 2 2 2 Opioid growth factor receptor repeat DUF968 PF06147.6 KEG05339.1 - 0.0066 16.3 0.3 0.009 15.9 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF968) DUF922 PF06037.6 KEG05339.1 - 0.022 14.0 0.1 0.027 13.7 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF922) NTF2 PF02136.15 KEG05341.1 - 1.5e-27 96.2 0.0 1.7e-27 96.1 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain SnoaL_2 PF12680.2 KEG05341.1 - 0.0017 18.7 0.0 0.0021 18.4 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain Lumazine_bd_2 PF12893.2 KEG05341.1 - 0.019 15.4 0.0 0.03 14.8 0.0 1.3 1 0 0 1 1 1 0 Putative lumazine-binding DUF4440 PF14534.1 KEG05341.1 - 0.04 14.1 0.0 0.048 13.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) zf-Di19 PF05605.7 KEG05342.1 - 0.0099 15.9 0.4 0.022 14.8 0.3 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding DUF2752 PF10825.3 KEG05342.1 - 0.13 12.2 0.5 0.39 10.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2752) zf-nanos PF05741.8 KEG05342.1 - 0.68 9.9 4.0 11 6.0 0.3 2.4 1 1 0 2 2 2 0 Nanos RNA binding domain zf-C2H2 PF00096.21 KEG05342.1 - 0.7 10.3 3.5 2.1 8.8 2.4 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type YrzO PF14142.1 KEG05345.1 - 0.0026 17.3 0.2 0.0042 16.6 0.2 1.3 1 0 0 1 1 1 1 YrzO-like protein Rogdi_lz PF10259.4 KEG05346.1 - 0.00029 20.0 1.5 0.00029 20.0 1.0 1.9 1 1 1 2 2 2 1 Rogdi leucine zipper containing protein Exonuc_VII_L PF02601.10 KEG05346.1 - 0.0041 16.3 13.1 0.024 13.8 3.7 2.2 2 0 0 2 2 2 2 Exonuclease VII, large subunit HOOK PF05622.7 KEG05346.1 - 0.024 12.4 16.2 0.067 11.0 4.3 2.8 3 0 0 3 3 3 0 HOOK protein DUF4206 PF13901.1 KEG05346.1 - 0.042 13.3 0.9 3 7.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4206) Seryl_tRNA_N PF02403.17 KEG05346.1 - 0.085 12.8 16.8 0.64 10.0 3.9 3.3 3 1 1 4 4 3 0 Seryl-tRNA synthetase N-terminal domain DUF3138 PF11336.3 KEG05346.1 - 0.09 10.9 6.1 0.17 10.0 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Tropomyosin PF00261.15 KEG05346.1 - 0.14 11.2 20.6 0.4 9.7 0.0 3.3 3 0 0 3 3 3 0 Tropomyosin DUF1690 PF07956.6 KEG05346.1 - 0.29 11.1 6.6 0.78 9.7 1.1 2.8 2 1 1 3 3 3 0 Protein of Unknown function (DUF1690) DivIC PF04977.10 KEG05346.1 - 0.33 10.4 20.7 0.25 10.8 0.4 4.1 2 1 2 4 4 4 0 Septum formation initiator TPR_MLP1_2 PF07926.7 KEG05346.1 - 0.73 9.5 23.0 0.85 9.3 5.2 3.5 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4200 PF13863.1 KEG05346.1 - 0.83 9.6 22.4 2.1 8.2 0.9 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4200) Macoilin PF09726.4 KEG05346.1 - 0.85 7.8 11.7 1.8 6.7 8.1 1.6 1 1 0 1 1 1 0 Transmembrane protein CCDC-167 PF15188.1 KEG05346.1 - 0.85 9.6 17.2 1.2 9.1 3.1 3.6 3 2 0 3 3 3 0 Coiled-coil domain-containing protein 167 DUF928 PF06051.7 KEG05346.1 - 1.4 8.4 6.0 1.3 8.6 2.9 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF928) Fib_alpha PF08702.5 KEG05346.1 - 1.7 8.7 9.2 5.1 7.2 0.1 3.2 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family YlqD PF11068.3 KEG05346.1 - 3.1 7.8 18.2 5 7.1 2.8 3.3 3 1 0 3 3 3 0 YlqD protein MxiH PF09392.5 KEG05346.1 - 4.4 7.9 10.4 99 3.6 7.2 2.9 1 1 0 1 1 1 0 Type III secretion needle MxiH like DUF972 PF06156.8 KEG05346.1 - 4.5 7.6 16.0 2.9 8.2 0.8 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF972) DUF1664 PF07889.7 KEG05346.1 - 4.7 7.0 7.5 2.6 7.8 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Sec3_C PF09763.4 KEG05350.1 - 1.2e-42 146.0 0.3 1.3e-42 145.8 0.2 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec3 GAS PF13851.1 KEG05350.1 - 0.0054 15.9 0.2 0.013 14.7 0.1 1.6 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Hemerythrin PF01814.18 KEG05350.1 - 0.016 15.3 4.9 0.037 14.1 0.0 3.3 2 1 0 3 3 3 0 Hemerythrin HHE cation binding domain DUF3851 PF12962.2 KEG05350.1 - 0.023 14.6 0.0 0.057 13.4 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3851) DUF972 PF06156.8 KEG05350.1 - 0.032 14.5 2.4 0.045 14.1 0.9 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF972) TMCO5 PF14992.1 KEG05350.1 - 0.047 12.8 0.0 0.16 11.0 0.1 1.7 2 0 0 2 2 2 0 TMCO5 family DASH_Dam1 PF08653.5 KEG05350.1 - 0.068 12.9 2.0 0.63 9.8 0.1 2.9 4 0 0 4 4 4 0 DASH complex subunit Dam1 DUF3467 PF11950.3 KEG05353.1 - 0.42 10.6 2.6 13 5.8 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3467) Flavokinase PF01687.12 KEG05354.1 - 2.9e-16 59.4 0.0 3.2e-16 59.3 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase BP28CT PF08146.7 KEG05355.1 - 0.02 14.6 0.3 0.2 11.3 0.0 2.4 3 0 0 3 3 3 0 BP28CT (NUC211) domain ACT_6 PF13740.1 KEG05355.1 - 0.46 10.2 3.3 21 4.8 0.1 3.4 3 1 0 3 3 3 0 ACT domain ZapA PF05164.8 KEG05355.1 - 4.9 7.1 6.3 2.4 8.2 0.2 2.8 3 0 0 3 3 3 0 Cell division protein ZapA IncA PF04156.9 KEG05356.1 - 0.025 14.1 0.0 0.036 13.6 0.0 1.1 1 0 0 1 1 1 0 IncA protein Sensor PF13796.1 KEG05356.1 - 0.04 13.5 0.1 0.06 12.9 0.1 1.3 1 0 0 1 1 1 0 Putative sensor DUF1191 PF06697.7 KEG05356.1 - 0.04 12.7 0.0 0.058 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) EphA2_TM PF14575.1 KEG05356.1 - 0.043 14.2 0.0 0.082 13.3 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain P12 PF12669.2 KEG05356.1 - 0.07 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Virus attachment protein p12 family CD34_antigen PF06365.7 KEG05356.1 - 0.092 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family VSP PF03302.8 KEG05356.1 - 2.3 6.7 4.6 3.2 6.2 3.2 1.3 1 1 0 1 1 1 0 Giardia variant-specific surface protein MIF4G_like_2 PF09090.6 KEG05357.1 - 0.11 11.7 3.4 0.26 10.4 0.5 2.5 1 1 2 3 3 3 0 MIF4G like DUF2749 PF10907.3 KEG05357.1 - 0.56 10.1 2.6 2.3 8.1 1.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2749) DUF2150 PF09920.4 KEG05357.1 - 1.1 8.8 7.8 0.084 12.4 0.7 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2150) Serine_rich PF08824.5 KEG05357.1 - 5.3 6.7 11.5 0.18 11.4 1.8 2.6 2 1 1 3 3 3 0 Serine rich protein interaction domain DUF2229 PF09989.4 KEG05357.1 - 5.5 6.3 7.7 11 5.4 0.7 2.2 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) Ribosomal_60s PF00428.14 KEG05359.1 - 4.6 7.6 8.5 4 7.8 2.0 2.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF3325 PF11804.3 KEG05360.1 - 0.048 13.6 0.3 0.075 12.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3325) DED PF01335.16 KEG05361.1 - 0.081 13.0 0.5 1.1 9.4 0.0 2.9 4 1 0 4 4 4 0 Death effector domain Peptidase_M9_N PF08453.5 KEG05361.1 - 0.58 9.4 8.1 0.9 8.8 2.6 2.5 2 1 0 2 2 2 0 Peptidase family M9 N-terminal TMF_DNA_bd PF12329.3 KEG05361.1 - 0.75 9.6 14.9 0.11 12.2 1.7 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4242 PF14026.1 KEG05361.1 - 0.91 9.6 5.2 1.8 8.7 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4242) MCPsignal PF00015.16 KEG05361.1 - 1.4 8.4 29.2 0.24 10.9 4.3 2.6 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain PXA PF02194.10 KEG05361.1 - 7.5 6.0 8.5 14 5.2 5.7 1.8 1 1 1 2 2 2 0 PXA domain Pet191_N PF10203.4 KEG05362.1 - 0.19 11.7 1.1 0.26 11.3 0.8 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Flagellar_rod PF05149.7 KEG05368.1 - 0.0018 17.5 2.5 0.0018 17.5 1.7 2.5 3 0 0 3 3 3 1 Paraflagellar rod protein Reo_sigmaC PF04582.7 KEG05368.1 - 0.0096 15.1 6.0 0.047 12.8 0.6 2.2 2 0 0 2 2 2 1 Reovirus sigma C capsid protein Med9 PF07544.8 KEG05368.1 - 0.027 14.2 1.8 0.027 14.2 1.3 3.4 3 1 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Katanin_con80 PF13925.1 KEG05368.1 - 0.059 13.1 3.2 0.062 13.0 0.8 2.0 1 1 0 1 1 1 0 con80 domain of Katanin DUF16 PF01519.11 KEG05368.1 - 0.2 11.8 5.5 2.6 8.3 0.6 2.8 3 0 0 3 3 3 0 Protein of unknown function DUF16 Tropomyosin PF00261.15 KEG05368.1 - 0.21 10.6 22.5 0.011 14.8 5.5 3.2 1 1 2 3 3 3 0 Tropomyosin DivIVA PF05103.8 KEG05368.1 - 0.26 11.3 19.7 0.38 10.8 0.1 3.2 3 1 0 3 3 3 0 DivIVA protein NPV_P10 PF05531.7 KEG05368.1 - 0.27 11.5 5.1 1.8 8.8 0.1 3.6 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.2 KEG05368.1 - 0.31 10.8 23.1 0.24 11.2 7.6 3.0 2 2 1 3 3 3 0 Tropomyosin like DUF904 PF06005.7 KEG05368.1 - 0.36 11.1 10.3 1.1 9.6 0.1 4.1 3 1 0 3 3 3 0 Protein of unknown function (DUF904) DUF3040 PF11239.3 KEG05368.1 - 0.49 10.4 2.9 1.2 9.2 2.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DASH_Dad2 PF08654.5 KEG05368.1 - 1 9.4 9.0 0.39 10.7 0.1 3.0 3 0 0 3 3 2 0 DASH complex subunit Dad2 COG5 PF10392.4 KEG05368.1 - 1.1 9.2 9.1 1.5 8.8 0.1 3.2 3 0 0 3 3 3 0 Golgi transport complex subunit 5 CCDC-167 PF15188.1 KEG05368.1 - 1.3 9.0 0.0 1.3 9.0 0.0 3.3 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 YlqD PF11068.3 KEG05368.1 - 2.4 8.1 0.0 2.4 8.1 0.0 3.1 3 0 0 3 3 3 0 YlqD protein SlyX PF04102.7 KEG05368.1 - 2.8 8.3 13.7 9.8 6.6 0.0 4.2 2 2 1 3 3 3 0 SlyX YebO PF13974.1 KEG05368.1 - 2.9 7.7 5.8 10 5.9 4.0 1.9 1 0 0 1 1 1 0 YebO-like protein Fib_alpha PF08702.5 KEG05368.1 - 3.8 7.6 7.8 29 4.7 0.0 3.3 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Striatin PF08232.7 KEG05368.1 - 5.2 7.3 15.2 3.8 7.8 3.5 2.9 2 1 0 2 2 2 0 Striatin family FhuF PF06276.7 KEG05368.1 - 5.5 6.9 9.8 1.2 9.0 0.3 2.9 2 1 0 3 3 3 0 Ferric iron reductase FhuF-like transporter Atg14 PF10186.4 KEG05368.1 - 9.1 5.1 21.9 0.59 9.0 0.1 2.8 2 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 ADIP PF11559.3 KEG05368.1 - 9.6 6.0 23.7 1.2 9.0 7.0 3.3 3 2 0 3 3 3 0 Afadin- and alpha -actinin-Binding Mucin PF01456.12 KEG05369.1 - 7.3e-06 25.8 33.3 1.8e-05 24.5 17.3 3.2 2 1 0 2 2 2 2 Mucin-like glycoprotein PPR_2 PF13041.1 KEG05370.1 - 0.006 16.5 1.1 2.9 7.9 0.1 2.6 2 1 1 3 3 3 2 PPR repeat family DUF3883 PF13020.1 KEG05371.1 - 1.5e-17 63.1 0.0 2.1e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) Tox-WTIP PF15654.1 KEG05371.1 - 0.02 14.4 0.6 0.054 13.1 0.1 1.9 2 0 0 2 2 2 0 Toxin with a conserved tryptophan and TIP tripeptide motif DUF2533 PF10752.4 KEG05372.1 - 0.058 13.6 0.4 0.058 13.6 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2533) Allexi_40kDa PF05549.6 KEG05372.1 - 5.7 6.1 11.6 0.54 9.4 2.7 2.4 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF4404 PF14357.1 KEG05372.1 - 6.1 7.3 12.7 3 8.3 0.9 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) PAP1 PF08601.5 KEG05372.1 - 9.4 5.8 26.8 1.6 8.3 15.6 1.8 1 1 1 2 2 2 0 Transcription factor PAP1 LRR_8 PF13855.1 KEG05373.1 - 0.0045 16.7 0.0 0.0075 15.9 0.0 1.4 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 KEG05373.1 - 0.013 15.4 0.0 0.33 11.1 0.0 2.8 3 0 0 3 3 3 0 Leucine Rich Repeat LRRNT_2 PF08263.7 KEG05373.1 - 0.015 15.2 1.1 0.035 14.0 0.1 2.0 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain LRR_6 PF13516.1 KEG05373.1 - 0.018 15.0 0.4 0.055 13.5 0.3 1.9 1 1 0 1 1 1 0 Leucine Rich repeat LRR_4 PF12799.2 KEG05373.1 - 0.023 14.2 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) Amastin PF07344.6 KEG05374.1 - 5.3e-09 35.8 7.5 1e-08 34.9 4.5 1.8 1 1 0 1 1 1 1 Amastin surface glycoprotein ASFV_J13L PF05568.6 KEG05374.1 - 0.39 10.2 0.0 0.39 10.2 0.0 2.4 3 0 0 3 3 3 0 African swine fever virus J13L protein NicO PF03824.11 KEG05374.1 - 2.1 7.6 8.9 0.12 11.6 1.5 2.1 2 0 0 2 2 2 0 High-affinity nickel-transport protein Ndc1_Nup PF09531.5 KEG05374.1 - 4.7 5.5 5.9 6.8 4.9 4.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PXA PF02194.10 KEG05375.1 - 0.35 10.3 3.7 0.28 10.7 1.5 1.7 1 1 1 2 2 2 0 PXA domain Antitoxin-MazE PF04014.13 KEG05376.1 - 0.012 15.2 0.4 1.6 8.5 0.1 2.3 1 1 1 2 2 2 0 Antidote-toxin recognition MazE ATP-synt_ab_N PF02874.18 KEG05376.1 - 0.075 13.2 0.0 19 5.5 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, beta-barrel domain VirJ PF06057.6 KEG05376.1 - 0.13 11.9 0.0 2.1 8.0 0.0 2.0 1 1 0 1 1 1 0 Bacterial virulence protein (VirJ) Isochorismatase PF00857.15 KEG05379.1 - 1e-14 54.8 0.1 1.3e-14 54.5 0.1 1.0 1 0 0 1 1 1 1 Isochorismatase family DUF1886 PF09171.5 KEG05380.1 - 0.026 13.5 0.3 0.089 11.8 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1886) DisA-linker PF10635.4 KEG05380.1 - 0.055 12.9 0.0 0.099 12.1 0.0 1.5 1 0 0 1 1 1 0 DisA bacterial checkpoint controller linker region MmoB_DmpM PF02406.12 KEG05380.1 - 0.062 13.2 0.0 0.11 12.4 0.0 1.5 1 1 0 1 1 1 0 MmoB/DmpM family DUF3584 PF12128.3 KEG05380.1 - 0.067 10.5 1.9 0.09 10.0 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF503 PF04456.7 KEG05380.1 - 0.19 11.3 3.1 0.25 10.9 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF503) Tropomyosin_1 PF12718.2 KEG05380.1 - 0.2 11.5 3.1 0.4 10.5 0.3 2.2 1 1 1 2 2 2 0 Tropomyosin like Plasmodium_HRP PF05403.6 KEG05381.1 - 0.091 12.3 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Plasmodium histidine-rich protein (HRPII/III) RVT_1 PF00078.22 KEG05387.1 - 0.00034 20.0 0.0 0.00043 19.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3829 PF12889.2 KEG05389.1 - 8.3e-05 21.9 22.6 0.0014 17.9 4.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3829) IncA PF04156.9 KEG05389.1 - 0.0014 18.2 0.5 0.19 11.3 0.1 2.2 1 1 0 2 2 2 2 IncA protein Sec8_exocyst PF04048.9 KEG05389.1 - 0.15 11.7 5.0 0.2 11.2 0.7 2.7 1 1 2 3 3 3 0 Sec8 exocyst complex component specific domain Syntaxin-18_N PF10496.4 KEG05389.1 - 0.43 10.4 7.0 4.3 7.2 2.2 3.1 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus Imm5 PF14423.1 KEG05389.1 - 0.57 9.7 4.3 0.48 10.0 0.7 2.4 1 1 2 3 3 3 0 Immunity protein Imm5 Reo_sigmaC PF04582.7 KEG05389.1 - 1.1 8.3 13.0 0.19 10.8 5.8 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 KEG05389.1 - 2.9 7.7 13.0 1.3 8.9 3.8 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AF0941-like PF14591.1 KEG05389.1 - 4.9 7.2 8.5 0.95 9.5 2.8 2.2 2 1 0 2 2 2 0 AF0941-like Exonuc_VII_S PF02609.11 KEG05389.1 - 7.2 6.4 6.7 1.3 8.8 0.4 2.9 4 0 0 4 4 4 0 Exonuclease VII small subunit DUF1644 PF07800.7 KEG05390.1 - 0.001 18.9 2.9 0.0012 18.6 2.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1644) Peptidase_C7 PF01830.13 KEG05390.1 - 0.062 12.4 0.9 0.062 12.4 0.6 1.2 1 0 0 1 1 1 0 Peptidase C7 family DUF552 PF04472.7 KEG05394.1 - 0.018 14.9 0.1 0.054 13.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF552) IQ PF00612.22 KEG05395.1 - 0.0003 20.1 0.9 0.00061 19.2 0.2 1.9 2 0 0 2 2 2 1 IQ calmodulin-binding motif DUF1870 PF08965.5 KEG05395.1 - 0.038 13.6 0.2 0.042 13.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1870) ELO PF01151.13 KEG05398.1 - 8.9e-59 198.8 10.2 1e-58 198.6 7.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family C2 PF00168.25 KEG05400.1 - 0.098 12.5 0.0 0.2 11.5 0.0 1.6 1 1 0 1 1 1 0 C2 domain Mn_catalase PF05067.7 KEG05400.1 - 0.16 10.6 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Manganese containing catalase UBA PF00627.26 KEG05401.1 - 0.002 17.9 0.1 0.0041 16.9 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Macoilin PF09726.4 KEG05402.1 - 4.2 5.5 7.1 4.4 5.4 4.9 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF605 PF04652.11 KEG05402.1 - 7.7 5.8 14.7 9.4 5.5 10.2 1.1 1 0 0 1 1 1 0 Vta1 like OGFr_III PF04680.8 KEG05403.1 - 0.067 13.3 0.1 0.22 11.6 0.1 1.9 1 0 0 1 1 1 0 Opioid growth factor receptor repeat EF-hand_8 PF13833.1 KEG05405.1 - 0.22 11.1 1.4 9 6.0 0.5 2.4 2 0 0 2 2 2 0 EF-hand domain pair Mucin PF01456.12 KEG05406.1 - 0.43 10.3 17.0 1.7 8.3 11.8 2.1 1 1 0 1 1 1 0 Mucin-like glycoprotein DUF4473 PF14747.1 KEG05406.1 - 0.65 10.2 7.2 1.4 9.1 1.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) TLE_N PF03920.10 KEG05406.1 - 0.84 9.4 6.4 0.14 11.9 1.5 1.7 2 1 0 2 2 2 0 Groucho/TLE N-terminal Q-rich domain Cytochrom_C552 PF02335.10 KEG05406.1 - 1.2 7.7 10.1 1.5 7.4 7.0 1.1 1 0 0 1 1 1 0 Cytochrome c552 Senescence PF06911.7 KEG05406.1 - 1.2 8.8 11.8 0.044 13.4 2.6 2.2 1 1 1 2 2 2 0 Senescence-associated protein DUF2413 PF10310.4 KEG05406.1 - 1.7 7.4 15.6 7 5.3 10.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2413) ThylakoidFormat PF11264.3 KEG05406.1 - 4.1 6.9 7.4 1 8.9 1.2 2.0 1 1 0 2 2 2 0 Thylakoid formation protein Ribosomal_L12 PF00542.14 KEG05406.1 - 9.3 6.3 13.2 0.34 10.9 3.2 2.5 2 1 0 2 2 2 0 Ribosomal protein L7/L12 C-terminal domain SGT1 PF07093.6 KEG05407.1 - 0.058 11.7 7.7 0.059 11.7 5.4 1.1 1 0 0 1 1 1 0 SGT1 protein Spt5_N PF11942.3 KEG05407.1 - 3.5 8.2 20.3 24 5.5 11.4 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal zf-MYND PF01753.13 KEG05408.1 - 4.2e-06 26.5 10.7 4.2e-06 26.5 7.4 2.7 2 2 0 2 2 2 1 MYND finger TPR_16 PF13432.1 KEG05408.1 - 0.00024 21.6 4.5 0.0071 16.9 0.4 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEG05408.1 - 0.44 10.5 2.7 28 4.9 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 KEG05408.1 - 1.9 8.2 5.6 2.4 7.8 1.5 2.6 1 1 2 3 3 3 0 TPR repeat CAF-1_p150 PF11600.3 KEG05409.1 - 0.025 13.9 40.6 0.032 13.6 28.2 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Borrelia_P83 PF05262.6 KEG05409.1 - 0.063 11.5 26.7 0.071 11.3 18.5 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Hid1 PF12722.2 KEG05409.1 - 0.37 8.4 6.9 0.41 8.2 4.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein APG6 PF04111.7 KEG05409.1 - 0.44 9.5 22.2 0.62 9.0 15.4 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Asp-B-Hydro_N PF05279.6 KEG05409.1 - 0.55 10.0 31.8 0.75 9.5 22.0 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Ycf1 PF05758.7 KEG05409.1 - 0.6 7.7 13.2 0.77 7.3 9.1 1.3 1 0 0 1 1 1 0 Ycf1 Mucin PF01456.12 KEG05409.1 - 0.93 9.2 7.1 2.4 7.9 4.2 2.2 1 1 0 1 1 1 0 Mucin-like glycoprotein RAP1 PF07218.6 KEG05409.1 - 0.94 7.4 7.0 0.98 7.4 4.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DDHD PF02862.12 KEG05409.1 - 1.1 9.0 13.6 1.6 8.4 9.5 1.4 1 0 0 1 1 1 0 DDHD domain Parvo_coat PF00740.13 KEG05409.1 - 2.5 6.9 4.8 2.7 6.8 3.3 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 PLRV_ORF5 PF01690.12 KEG05409.1 - 3 6.8 15.7 3.5 6.6 10.9 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein LMBR1 PF04791.11 KEG05409.1 - 6.3 5.2 7.7 7.5 5.0 5.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Draxin PF15550.1 KEG05409.1 - 7.1 6.1 17.1 9.3 5.8 11.9 1.1 1 0 0 1 1 1 0 Draxin DUF572 PF04502.8 KEG05409.1 - 8.1 5.5 27.8 10 5.2 19.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Pilt PF15453.1 KEG05409.1 - 9.2 5.8 19.6 12 5.4 13.6 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions MAP65_ASE1 PF03999.7 KEG05410.1 - 0.072 11.6 0.1 0.12 10.9 0.1 1.3 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) IncA PF04156.9 KEG05410.1 - 0.1 12.1 1.9 0.2 11.1 1.3 1.4 1 0 0 1 1 1 0 IncA protein Mucin PF01456.12 KEG05412.1 - 0.054 13.2 7.9 0.082 12.6 5.5 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Podoplanin PF05808.6 KEG05412.1 - 10 5.6 9.7 16 4.9 6.6 1.4 1 1 0 1 1 1 0 Podoplanin Mucin PF01456.12 KEG05414.1 - 2.2e-08 33.9 3.6 2.2e-08 33.9 2.5 2.7 2 1 0 2 2 2 1 Mucin-like glycoprotein HisKA PF00512.20 KEG05415.1 - 0.018 15.0 0.2 0.3 11.1 0.0 2.8 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain Acetyltransf_11 PF13720.1 KEG05415.1 - 0.33 11.2 1.8 4.6 7.5 0.1 3.0 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 ATG_C PF09333.6 KEG05415.1 - 0.69 10.0 12.2 0.47 10.6 0.8 3.3 2 1 0 3 3 3 0 ATG C terminal domain Peptidase_M32 PF02074.10 KEG05415.1 - 2 6.9 6.0 0.55 8.7 0.4 2.0 2 0 0 2 2 2 0 Carboxypeptidase Taq (M32) metallopeptidase HisKA_3 PF07730.8 KEG05415.1 - 2.9 8.3 12.0 0.75 10.1 0.1 4.0 4 1 0 4 4 4 0 Histidine kinase Brix PF04427.13 KEG05416.1 - 3.7e-20 72.4 0.0 4.5e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Brix domain Shisa PF13908.1 KEG05420.1 - 0.0038 17.4 2.0 0.0051 17.0 0.3 1.8 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator TrbL PF04610.9 KEG05420.1 - 0.0057 16.3 0.8 0.0095 15.6 0.2 1.6 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein DUF1191 PF06697.7 KEG05420.1 - 0.0088 14.8 0.1 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Rifin_STEVOR PF02009.11 KEG05420.1 - 0.016 14.8 0.1 0.033 13.8 0.0 1.5 2 0 0 2 2 2 0 Rifin/stevor family IncA PF04156.9 KEG05420.1 - 0.032 13.8 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 IncA protein TRAP_alpha PF03896.11 KEG05420.1 - 0.04 12.9 0.0 0.077 11.9 0.0 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit P12 PF12669.2 KEG05420.1 - 0.043 14.0 0.9 0.067 13.3 0.6 1.2 1 0 0 1 1 1 0 Virus attachment protein p12 family EphA2_TM PF14575.1 KEG05420.1 - 0.046 14.1 0.0 0.095 13.1 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Sensor PF13796.1 KEG05420.1 - 0.083 12.4 0.4 0.13 11.8 0.2 1.3 1 0 0 1 1 1 0 Putative sensor Mucin PF01456.12 KEG05421.1 - 2.5e-07 30.5 48.5 0.0061 16.3 11.8 3.1 1 1 1 2 2 2 2 Mucin-like glycoprotein SURF2 PF05477.6 KEG05421.1 - 0.68 9.0 4.9 1.1 8.3 3.4 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) tRNA-synt_1c_C PF03950.13 KEG05422.1 - 0.078 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain DUF4175 PF13779.1 KEG05422.1 - 0.086 10.5 1.2 0.17 9.5 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) NTP_transf_3 PF12804.2 KEG05423.1 - 0.034 14.2 0.1 0.083 12.9 0.1 1.7 1 0 0 1 1 1 0 MobA-like NTP transferase domain Phage_Gp111 PF07410.6 KEG05428.1 - 0.27 11.3 4.1 0.23 11.6 0.5 2.5 1 1 1 2 2 2 0 Streptococcus thermophilus bacteriophage Gp111 protein FliJ PF02050.11 KEG05429.1 - 0.002 18.1 5.0 0.038 14.0 1.8 2.2 2 0 0 2 2 2 1 Flagellar FliJ protein Mucin PF01456.12 KEG05429.1 - 0.0025 17.6 4.6 0.0051 16.6 3.3 1.6 1 1 0 1 1 1 1 Mucin-like glycoprotein IncA PF04156.9 KEG05429.1 - 0.026 14.1 3.5 4.2 6.9 1.8 2.2 2 0 0 2 2 2 0 IncA protein DUF1957 PF09210.6 KEG05429.1 - 0.029 14.4 0.5 9.5 6.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1957) Phi-29_GP3 PF05435.6 KEG05429.1 - 0.031 13.4 0.3 0.046 12.9 0.2 1.3 1 0 0 1 1 1 0 Phi-29 DNA terminal protein GP3 Lectin_N PF03954.9 KEG05429.1 - 0.073 12.4 1.5 9.8 5.5 0.0 2.9 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain RPW8 PF05659.6 KEG05429.1 - 0.079 12.5 2.0 0.2 11.1 0.3 2.1 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF4168 PF13767.1 KEG05429.1 - 0.13 12.9 1.7 0.2 12.3 0.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4168) Pox_vIL-18BP PF05566.7 KEG05429.1 - 0.13 12.2 0.0 6.5 6.7 0.0 2.4 1 1 1 2 2 2 0 Orthopoxvirus interleukin 18 binding protein DUF1307 PF06998.6 KEG05429.1 - 0.2 11.7 2.6 0.12 12.4 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1307) HOOK PF05622.7 KEG05429.1 - 0.25 9.1 7.5 0.06 11.1 1.4 1.9 2 0 0 2 2 2 0 HOOK protein ATP-synt_B PF00430.13 KEG05429.1 - 0.26 11.0 8.2 3.1 7.6 0.3 2.5 2 1 1 3 3 3 0 ATP synthase B/B' CF(0) Synaptobrevin PF00957.16 KEG05429.1 - 0.29 10.7 3.4 3.1 7.4 0.3 2.6 2 0 0 2 2 2 0 Synaptobrevin Tropomyosin PF00261.15 KEG05429.1 - 0.35 9.9 8.6 0.083 11.9 1.0 2.1 2 0 0 2 2 2 0 Tropomyosin Snapin_Pallidin PF14712.1 KEG05429.1 - 0.6 10.4 5.8 8.6 6.7 0.0 3.0 2 1 1 3 3 3 0 Snapin/Pallidin DUF2277 PF10041.4 KEG05429.1 - 0.79 9.7 4.9 0.97 9.4 0.3 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2277) SNARE PF05739.14 KEG05429.1 - 0.97 9.1 5.6 1.5 8.5 0.1 3.1 3 0 0 3 3 3 0 SNARE domain LUC7 PF03194.10 KEG05429.1 - 2.3 7.6 7.7 3.4 7.1 0.6 2.2 1 1 0 2 2 2 0 LUC7 N_terminus MxiH PF09392.5 KEG05429.1 - 3.9 8.0 10.9 11 6.7 1.8 2.6 1 1 1 2 2 2 0 Type III secretion needle MxiH like COG2 PF06148.6 KEG05429.1 - 4.4 7.1 7.0 6.7 6.5 1.2 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TMF_DNA_bd PF12329.3 KEG05429.1 - 5.2 6.9 10.6 2.7 7.8 0.2 3.2 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF948 PF06103.6 KEG05429.1 - 5.5 6.9 9.0 5.2 6.9 0.5 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF3713 PF12506.3 KEG05429.1 - 9.5 6.3 8.9 2.2 8.4 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3713) Cut8_N PF14482.1 KEG05430.1 - 0.018 15.0 0.0 0.026 14.5 0.0 1.2 1 0 0 1 1 1 0 Cut8 proteasome-binding domain DUF3439 PF11921.3 KEG05431.1 - 0.0074 16.0 3.3 0.014 15.1 2.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Sporozoite_P67 PF05642.6 KEG05431.1 - 0.017 13.0 4.6 0.019 12.8 3.2 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen mRNA_cap_C PF03919.10 KEG05432.1 - 0.024 14.9 1.6 0.048 13.9 0.4 1.9 2 0 0 2 2 2 0 mRNA capping enzyme, C-terminal domain Atg14 PF10186.4 KEG05432.1 - 0.073 12.0 14.3 0.21 10.4 3.1 2.6 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 MitMem_reg PF13012.1 KEG05432.1 - 0.099 12.7 5.9 2.2 8.3 0.6 2.8 2 1 1 3 3 3 0 Maintenance of mitochondrial structure and function DUF1664 PF07889.7 KEG05432.1 - 1.8 8.3 10.6 0.24 11.2 0.4 2.7 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) P4Ha_N PF08336.6 KEG05432.1 - 9.3 6.0 7.7 3.9 7.3 0.2 3.3 2 1 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region RabGAP-TBC PF00566.13 KEG05433.1 - 4 6.8 4.9 3.5 7.0 2.3 1.7 1 1 0 1 1 1 0 Rab-GTPase-TBC domain LRR_4 PF12799.2 KEG05434.1 - 9.5e-12 44.2 14.6 1.5e-07 30.8 1.3 2.9 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 KEG05434.1 - 6e-09 35.6 0.0 1.2e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 KEG05434.1 - 5.6e-05 22.8 2.2 0.00018 21.1 1.5 1.9 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 KEG05434.1 - 0.089 12.8 5.4 1.7 8.9 0.1 4.0 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_7 PF13504.1 KEG05434.1 - 0.69 10.3 9.0 3.4 8.2 0.2 4.5 4 0 0 4 4 4 0 Leucine rich repeat API5 PF05918.6 KEG05437.1 - 7.4 4.9 13.1 8.9 4.6 9.1 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF2775 PF10950.3 KEG05439.1 - 0.013 15.6 0.9 0.027 14.6 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2775) Rotamase_2 PF13145.1 KEG05439.1 - 0.036 14.6 1.6 0.066 13.8 1.1 1.3 1 0 0 1 1 1 0 PPIC-type PPIASE domain OmpH PF03938.9 KEG05439.1 - 0.37 10.7 9.3 0.63 9.9 6.5 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Zip PF02535.17 KEG05440.1 - 0.0042 16.1 8.5 0.0051 15.8 5.9 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter LysM PF01476.15 KEG05441.1 - 2.4e-06 27.3 0.0 0.012 15.4 0.0 2.8 3 0 0 3 3 3 2 LysM domain Elong_Iki1 PF10483.4 KEG05443.1 - 0.069 12.5 0.0 0.083 12.2 0.0 1.1 1 0 0 1 1 1 0 Elongator subunit Iki1 Rieske PF00355.21 KEG05444.1 - 0.012 15.1 0.1 0.017 14.6 0.1 1.3 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain DUF4407 PF14362.1 KEG05445.1 - 0.08 11.8 3.7 0.081 11.8 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RVT_1 PF00078.22 KEG05446.1 - 3.1e-30 105.1 0.0 4.2e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Kelch_4 PF13418.1 KEG05447.1 - 0.096 12.4 0.5 3 7.7 0.0 2.8 2 1 0 2 2 2 0 Galactose oxidase, central domain zf-RanBP PF00641.13 KEG05449.1 - 0.022 13.8 15.8 0.052 12.6 6.2 2.8 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Cytochrom_CIII PF02085.11 KEG05449.1 - 0.028 14.4 0.3 0.028 14.4 0.2 2.0 2 0 0 2 2 2 0 Class III cytochrome C family zf-ribbon_3 PF13248.1 KEG05449.1 - 0.5 9.6 12.0 4.8 6.5 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 KEG05449.1 - 0.64 9.8 15.0 4.3 7.2 0.6 2.6 1 1 2 3 3 3 0 Double zinc ribbon zf-TFIIB PF13453.1 KEG05449.1 - 1.2 8.3 6.2 2.6 7.3 0.2 3.3 3 0 0 3 3 3 0 Transcription factor zinc-finger DNA_RNApol_7kD PF03604.8 KEG05449.1 - 8.2 5.9 7.3 10 5.6 1.5 2.9 2 1 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit SGS PF05002.10 KEG05450.1 - 1.3e-27 95.3 0.0 1.9e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 SGS domain CS PF04969.11 KEG05450.1 - 3.3e-08 33.9 0.0 4.5e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 CS domain CLN3 PF02487.12 KEG05451.1 - 8e-09 34.7 13.3 5.2e-08 32.0 4.7 2.1 1 1 1 2 2 2 2 CLN3 protein FAM165 PF14981.1 KEG05452.1 - 0.0017 17.8 0.2 0.0025 17.2 0.1 1.2 1 0 0 1 1 1 1 FAM165 family TTL PF03133.10 KEG05453.1 - 2.3e-05 23.4 0.1 4.3e-05 22.5 0.0 1.4 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family WD40 PF00400.27 KEG05455.1 - 3.9e-06 26.5 0.3 2.7e-05 23.8 0.1 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF2804 PF10974.3 KEG05456.1 - 2.5e-29 102.1 0.4 2.8e-29 102.0 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2804) TMF_TATA_bd PF12325.3 KEG05457.1 - 0.0003 20.5 12.4 0.00044 19.9 8.6 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding APG6 PF04111.7 KEG05457.1 - 0.003 16.6 13.8 0.0035 16.4 9.6 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 ADIP PF11559.3 KEG05457.1 - 0.016 15.1 16.0 0.02 14.8 11.1 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 KEG05457.1 - 0.026 14.8 10.4 0.047 14.0 7.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF4164 PF13747.1 KEG05457.1 - 0.027 14.5 17.0 0.12 12.5 11.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) HOOK PF05622.7 KEG05457.1 - 0.035 11.9 9.7 0.047 11.4 6.7 1.2 1 0 0 1 1 1 0 HOOK protein ERM PF00769.14 KEG05457.1 - 0.07 12.6 18.1 0.077 12.5 12.5 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family ATG16 PF08614.6 KEG05457.1 - 0.084 12.6 13.2 0.39 10.5 9.0 1.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF2968 PF11180.3 KEG05457.1 - 0.086 12.2 14.9 0.12 11.7 10.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) bZIP_1 PF00170.16 KEG05457.1 - 0.086 12.8 11.6 0.07 13.0 3.9 2.5 1 1 1 2 2 2 0 bZIP transcription factor Mod_r PF07200.8 KEG05457.1 - 0.098 12.5 11.4 0.13 12.1 7.9 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF3287 PF11690.3 KEG05457.1 - 0.11 12.6 5.2 0.045 13.8 1.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) Lectin_N PF03954.9 KEG05457.1 - 0.16 11.3 1.9 0.24 10.7 1.3 1.5 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain Prefoldin_2 PF01920.15 KEG05457.1 - 0.17 11.6 12.7 7.1 6.4 8.8 2.4 1 1 0 1 1 1 0 Prefoldin subunit TBPIP PF07106.8 KEG05457.1 - 0.2 11.2 8.5 0.23 10.9 5.9 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3584 PF12128.3 KEG05457.1 - 0.21 8.8 14.3 0.22 8.7 9.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TMCO5 PF14992.1 KEG05457.1 - 0.21 10.6 7.5 0.26 10.3 5.2 1.0 1 0 0 1 1 1 0 TMCO5 family IncA PF04156.9 KEG05457.1 - 0.27 10.8 16.6 0.31 10.6 11.5 1.1 1 0 0 1 1 1 0 IncA protein Fib_alpha PF08702.5 KEG05457.1 - 0.3 11.2 5.5 0.36 10.9 3.8 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF3450 PF11932.3 KEG05457.1 - 0.34 10.1 12.1 0.4 9.9 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) GAS PF13851.1 KEG05457.1 - 0.34 10.0 14.7 0.58 9.3 10.2 1.3 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Rab5-bind PF09311.6 KEG05457.1 - 0.37 10.6 17.1 0.49 10.2 11.8 1.2 1 0 0 1 1 1 0 Rabaptin-like protein Alpha-2-MRAP_C PF06401.6 KEG05457.1 - 0.38 10.5 7.6 1.5 8.6 5.3 1.7 1 1 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain CENP-F_N PF10481.4 KEG05457.1 - 0.47 9.7 11.7 0.56 9.5 8.1 1.0 1 0 0 1 1 1 0 Cenp-F N-terminal domain Mnd1 PF03962.10 KEG05457.1 - 0.49 10.0 11.8 0.69 9.5 8.2 1.2 1 0 0 1 1 1 0 Mnd1 family V_ATPase_I PF01496.14 KEG05457.1 - 0.55 8.0 7.4 0.6 7.8 5.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-H PF05837.7 KEG05457.1 - 0.58 10.3 9.5 1 9.5 6.6 1.5 1 1 0 1 1 1 0 Centromere protein H (CENP-H) CENP-Q PF13094.1 KEG05457.1 - 0.69 9.9 16.1 1 9.3 11.1 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit CtIP_N PF10482.4 KEG05457.1 - 0.8 9.5 12.2 1.1 9.0 4.7 2.1 1 1 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain DUF1204 PF06721.6 KEG05457.1 - 1 8.5 9.0 1.4 8.1 6.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) Ax_dynein_light PF10211.4 KEG05457.1 - 1 9.1 14.7 4 7.2 10.2 1.8 1 1 0 1 1 1 0 Axonemal dynein light chain Seryl_tRNA_N PF02403.17 KEG05457.1 - 1.1 9.3 13.3 1.8 8.6 9.2 1.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.6 KEG05457.1 - 1.1 7.8 9.6 1.5 7.4 6.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DivIC PF04977.10 KEG05457.1 - 1.3 8.5 19.8 0.48 9.9 7.2 2.9 1 1 2 3 3 3 0 Septum formation initiator Spc24 PF08286.6 KEG05457.1 - 1.4 8.6 10.8 1.5 8.5 4.0 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF2317 PF10079.4 KEG05457.1 - 1.5 7.3 11.8 1.6 7.2 8.2 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) HlyD PF00529.15 KEG05457.1 - 1.8 7.8 14.9 2.2 7.5 10.3 1.1 1 0 0 1 1 1 0 HlyD family secretion protein DUF904 PF06005.7 KEG05457.1 - 1.9 8.8 20.6 53 4.2 14.3 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF904) SecA_DEAD PF07517.9 KEG05457.1 - 2 7.6 6.2 2.3 7.4 4.3 1.1 1 0 0 1 1 1 0 SecA DEAD-like domain HALZ PF02183.13 KEG05457.1 - 2.1 8.1 12.7 0.056 13.1 2.3 2.9 2 1 0 3 3 3 0 Homeobox associated leucine zipper NYD-SP28_assoc PF14775.1 KEG05457.1 - 2.4 7.9 9.9 1.5 8.5 0.2 3.2 1 1 2 3 3 3 0 Sperm tail C-terminal domain AAA_13 PF13166.1 KEG05457.1 - 2.4 6.4 8.5 3.1 6.1 5.9 1.1 1 0 0 1 1 1 0 AAA domain DUF342 PF03961.8 KEG05457.1 - 2.8 6.2 5.2 3.5 5.9 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4263 PF14082.1 KEG05457.1 - 3 7.7 5.4 5.9 6.8 1.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4263) DASH_Spc34 PF08657.5 KEG05457.1 - 3.6 7.1 11.4 3.5 7.2 2.2 2.0 1 1 1 2 2 2 0 DASH complex subunit Spc34 LRS4 PF10422.4 KEG05457.1 - 3.8 6.7 7.9 4.8 6.4 5.5 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Elongin_A PF06881.6 KEG05457.1 - 4.4 7.7 9.5 2 8.8 4.3 1.8 1 1 1 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A zf-C4H2 PF10146.4 KEG05457.1 - 5.7 6.8 8.3 7.4 6.5 5.8 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein DUF724 PF05266.9 KEG05457.1 - 5.9 6.4 10.9 19 4.8 7.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF724) TMF_DNA_bd PF12329.3 KEG05457.1 - 5.9 6.7 15.1 11 5.9 5.3 2.2 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.7 KEG05457.1 - 6 6.6 17.1 27 4.5 11.8 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein OmpH PF03938.9 KEG05457.1 - 7 6.5 18.8 9.8 6.0 13.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FUSC PF04632.7 KEG05457.1 - 7.4 4.8 9.9 8.3 4.7 6.9 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Peptidase_M8 PF01457.11 KEG05458.1 - 4.5e-78 262.8 5.3 1.8e-76 257.5 3.6 2.0 1 1 0 1 1 1 1 Leishmanolysin Reprolysin_5 PF13688.1 KEG05458.1 - 0.016 15.1 0.1 0.04 13.8 0.0 1.7 2 0 0 2 2 2 0 Metallo-peptidase family M12 nlz1 PF12402.3 KEG05458.1 - 0.11 12.8 0.9 0.27 11.5 0.2 2.0 2 0 0 2 2 2 0 NocA-like zinc-finger protein 1 Peptidase_M10 PF00413.19 KEG05458.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Matrixin DUF479 PF04336.7 KEG05460.1 - 0.013 15.5 0.1 0.019 15.0 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF479 FUSC PF04632.7 KEG05460.1 - 0.015 13.7 8.0 0.018 13.5 5.5 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family JTB PF05439.7 KEG05465.1 - 0.018 14.7 0.1 1.6 8.5 0.0 2.1 2 0 0 2 2 2 0 Jumping translocation breakpoint protein (JTB) MSC PF09402.5 KEG05466.1 - 0.009 14.7 0.7 0.0099 14.6 0.5 1.0 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain 7TM_GPCR_Srv PF10323.4 KEG05466.1 - 0.012 14.7 0.9 0.013 14.5 0.6 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv EphA2_TM PF14575.1 KEG05466.1 - 0.018 15.4 0.3 0.024 15.0 0.2 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.1 KEG05466.1 - 0.077 13.1 0.2 0.095 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) RRN9 PF10680.4 KEG05466.1 - 0.12 12.1 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor CcmD PF04995.9 KEG05466.1 - 8.2 6.2 11.5 85 2.9 6.2 2.5 1 1 1 2 2 2 0 Heme exporter protein D (CcmD) DUF904 PF06005.7 KEG05468.1 - 0.0037 17.5 7.0 0.0037 17.5 4.8 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF904) ATG16 PF08614.6 KEG05468.1 - 0.012 15.4 28.2 0.13 12.0 3.2 3.1 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.4 KEG05468.1 - 0.013 15.3 27.2 0.064 13.1 10.1 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BTAD PF03704.12 KEG05468.1 - 0.014 15.7 4.0 0.014 15.7 2.8 2.3 2 1 0 3 3 3 0 Bacterial transcriptional activator domain TMF_TATA_bd PF12325.3 KEG05468.1 - 0.3 10.8 26.7 0.23 11.1 10.1 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding NPV_P10 PF05531.7 KEG05468.1 - 1.3 9.3 6.8 18 5.7 2.7 3.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein TPD52 PF04201.10 KEG05468.1 - 2.4 7.8 10.1 1.5 8.5 5.3 2.0 1 1 1 2 2 2 0 Tumour protein D52 family HALZ PF02183.13 KEG05468.1 - 2.7 7.7 10.2 6.3 6.5 0.7 3.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF4407 PF14362.1 KEG05468.1 - 3.1 6.6 15.4 14 4.5 10.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_13 PF13166.1 KEG05468.1 - 4 5.7 17.5 8.5 4.6 12.0 1.5 1 1 0 1 1 1 0 AAA domain DUF1028 PF06267.7 KEG05469.1 - 0.072 12.5 3.5 3.4 7.0 0.1 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF1028) DUF4463 PF14703.1 KEG05469.1 - 0.36 11.3 4.2 0.64 10.5 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4463) APC_CDC26 PF10471.4 KEG05469.1 - 4.1 8.1 14.7 12 6.7 5.8 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 DUF4106 PF13388.1 KEG05469.1 - 4.9 6.0 12.3 8.6 5.1 8.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Mucin PF01456.12 KEG05471.1 - 0.89 9.3 7.6 0.43 10.3 3.6 1.7 1 1 1 2 2 2 0 Mucin-like glycoprotein Transpep_BrtH PF14399.1 KEG05471.1 - 6.4 5.9 9.2 18 4.5 6.4 1.8 1 1 0 1 1 1 0 NlpC/p60-like transpeptidase WW PF00397.21 KEG05474.1 - 8e-09 35.2 0.2 1.5e-08 34.3 0.2 1.5 1 0 0 1 1 1 1 WW domain PsaD PF02531.11 KEG05474.1 - 0.077 12.1 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 PsaD ACBP PF00887.14 KEG05475.1 - 5.4e-30 102.8 0.2 6.1e-30 102.7 0.2 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein Ribosomal_L17 PF01196.14 KEG05476.1 - 0.19 12.2 2.7 0.14 12.7 0.5 1.8 2 0 0 2 2 2 0 Ribosomal protein L17 DUF3383 PF11863.3 KEG05476.1 - 0.98 8.0 16.4 0.48 9.0 9.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3383) DUF3355 PF11835.3 KEG05476.1 - 1.3 8.7 9.5 2.5 7.9 6.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3355) Rad21_Rec8 PF04824.11 KEG05481.1 - 7.7e-10 37.8 0.0 1.4e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 KEG05481.1 - 1.4e-05 24.8 0.0 1.7e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 ScpA/B protein USP8_dimer PF08969.6 KEG05483.1 - 0.017 15.0 0.4 0.038 13.9 0.3 1.6 1 0 0 1 1 1 0 USP8 dimerisation domain Mucin PF01456.12 KEG05484.1 - 8.3e-07 28.8 16.0 8.3e-07 28.8 11.1 4.2 1 1 4 5 5 5 2 Mucin-like glycoprotein Peptidase_M8 PF01457.11 KEG05485.1 - 2.4e-28 98.8 8.5 7.4e-26 90.5 5.9 2.0 1 1 0 1 1 1 1 Leishmanolysin SapA PF02199.10 KEG05485.1 - 0.17 11.6 1.5 0.77 9.5 1.1 2.2 1 1 0 1 1 1 0 Saposin A-type domain zf-CCCH PF00642.19 KEG05487.1 - 0.0047 16.5 3.2 0.0047 16.5 2.3 3.4 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KEG05487.1 - 2.7 8.1 9.1 4.1 7.5 0.1 3.2 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type Peptidase_C1 PF00112.18 KEG05488.1 - 8.1e-48 163.1 0.3 1.1e-47 162.7 0.2 1.2 1 0 0 1 1 1 1 Papain family cysteine protease DUF3586 PF12131.3 KEG05488.1 - 1.9e-23 82.2 9.6 2e-23 82.1 5.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3586) Peptidase_C1_2 PF03051.10 KEG05488.1 - 0.0069 14.9 0.0 0.0096 14.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase C1-like family Baculo_VP91_N PF08475.5 KEG05488.1 - 0.16 11.3 0.1 0.23 10.7 0.1 1.2 1 0 0 1 1 1 0 Viral capsid protein 91 N-terminal AftA_N PF12250.3 KEG05489.1 - 0.097 11.3 0.4 0.089 11.4 0.3 1.1 1 0 0 1 1 1 0 Arabinofuranosyltransferase N terminal HisKA_3 PF07730.8 KEG05490.1 - 0.14 12.5 4.9 0.46 10.8 0.2 3.3 3 0 0 3 3 3 0 Histidine kinase RB_B PF01857.15 KEG05491.1 - 0.1 12.1 0.1 0.13 11.7 0.1 1.1 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain Shisa PF13908.1 KEG05492.1 - 0.0067 16.6 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF2946 PF11162.3 KEG05492.1 - 0.014 15.6 0.1 0.1 12.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) EphA2_TM PF14575.1 KEG05492.1 - 0.023 15.0 0.0 0.038 14.3 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FAM163 PF15069.1 KEG05492.1 - 0.037 14.6 0.2 0.096 13.2 0.1 1.7 2 0 0 2 2 2 0 FAM163 family Rhabdo_glycop PF00974.13 KEG05492.1 - 0.039 12.2 0.2 0.058 11.6 0.2 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Herpes_gE PF02480.11 KEG05492.1 - 0.054 11.7 0.0 0.071 11.3 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DAP10 PF07213.6 KEG05492.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 DAP10 membrane protein Corona_S2 PF01601.11 KEG05492.1 - 0.11 10.6 4.9 0.16 10.0 3.4 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Herpes_glycop PF01528.11 KEG05492.1 - 0.12 11.0 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein M PAG PF15347.1 KEG05492.1 - 0.14 11.2 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched Vpu PF00558.14 KEG05492.1 - 0.17 11.4 0.1 0.28 10.7 0.1 1.3 1 0 0 1 1 1 0 Vpu protein Band_7 PF01145.20 KEG05494.1 - 0.02 14.8 3.1 1.3 8.8 0.4 2.4 2 0 0 2 2 2 0 SPFH domain / Band 7 family Mucin PF01456.12 KEG05494.1 - 0.033 13.9 4.4 0.037 13.8 0.0 3.0 3 1 0 3 3 3 0 Mucin-like glycoprotein SAICAR_synt PF01259.13 KEG05494.1 - 0.052 12.6 1.0 3.2 6.7 0.2 2.6 2 1 1 3 3 3 0 SAICAR synthetase DDE_Tnp_IS240 PF13610.1 KEG05494.1 - 0.39 10.6 3.2 1.5 8.7 0.0 2.7 3 0 0 3 3 3 0 DDE domain Spatacsin_C PF14649.1 KEG05494.1 - 0.72 8.6 3.6 0.26 10.1 0.2 1.9 2 0 0 2 2 2 0 Spatacsin C-terminus HrpF PF06266.7 KEG05494.1 - 2.2 8.4 5.1 2.3 8.3 0.5 2.6 3 0 0 3 3 3 0 HrpF protein CENP-H PF05837.7 KEG05495.1 - 0.052 13.7 4.2 0.12 12.5 2.9 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) TMF_DNA_bd PF12329.3 KEG05495.1 - 0.11 12.3 6.9 12 5.8 4.6 2.4 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Shugoshin_N PF07558.6 KEG05495.1 - 0.15 11.8 1.8 0.35 10.6 0.1 2.2 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DivIC PF04977.10 KEG05495.1 - 0.21 11.0 4.0 2.7 7.5 0.1 2.5 2 0 0 2 2 2 0 Septum formation initiator TMCO5 PF14992.1 KEG05495.1 - 0.26 10.3 4.1 0.42 9.6 2.8 1.3 1 0 0 1 1 1 0 TMCO5 family IncA PF04156.9 KEG05495.1 - 0.28 10.7 13.0 0.47 10.0 9.0 1.3 1 0 0 1 1 1 0 IncA protein TSC22 PF01166.13 KEG05495.1 - 0.43 10.5 4.3 3.2 7.8 0.2 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family HALZ PF02183.13 KEG05495.1 - 0.7 9.6 10.4 0.16 11.6 0.9 3.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper ATG16 PF08614.6 KEG05495.1 - 0.8 9.4 11.8 1.4 8.7 8.2 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Snapin_Pallidin PF14712.1 KEG05495.1 - 1.4 9.2 6.5 0.38 11.0 2.1 1.9 2 0 0 2 2 2 0 Snapin/Pallidin APG6 PF04111.7 KEG05495.1 - 2.3 7.1 6.4 3.5 6.5 4.5 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Lge1 PF11488.3 KEG05495.1 - 2.8 8.1 7.1 3 8.0 1.3 2.8 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 DUF972 PF06156.8 KEG05495.1 - 3.1 8.1 7.4 6 7.2 0.7 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) FUSC PF04632.7 KEG05495.1 - 6 5.1 14.1 8.2 4.7 9.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Viral_DNA_Zn_bi PF03728.8 KEG05496.1 - 0.0077 16.3 2.7 0.012 15.7 0.4 2.3 1 1 1 2 2 2 1 Viral DNA-binding protein, zinc binding domain DUF4170 PF13773.1 KEG05496.1 - 0.95 9.4 3.2 0.87 9.5 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4170) Pox_A_type_inc PF04508.7 KEG05497.1 - 0.2 11.5 0.0 0.2 11.5 0.0 3.6 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat DivIVA PF05103.8 KEG05497.1 - 0.31 11.0 9.6 0.41 10.7 6.5 1.3 1 1 0 1 1 1 0 DivIVA protein CCDC155 PF14662.1 KEG05498.1 - 0.00017 21.2 21.5 0.00043 19.9 14.9 1.7 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 DUF4200 PF13863.1 KEG05498.1 - 0.013 15.4 17.9 0.013 15.4 12.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Atg14 PF10186.4 KEG05498.1 - 0.023 13.6 18.3 0.041 12.8 12.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 AAA_13 PF13166.1 KEG05498.1 - 0.09 11.2 7.1 0.12 10.7 4.9 1.3 1 0 0 1 1 1 0 AAA domain DUF3123 PF11321.3 KEG05498.1 - 0.21 11.8 0.1 0.21 11.8 0.1 3.3 4 0 0 4 4 2 0 Protein of unknown function (DUF3123) Macoilin PF09726.4 KEG05498.1 - 0.24 9.6 17.1 0.38 8.9 11.9 1.2 1 0 0 1 1 1 0 Transmembrane protein Bacillus_HBL PF05791.6 KEG05498.1 - 0.26 10.6 5.9 0.56 9.5 3.8 1.8 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Spc7 PF08317.6 KEG05498.1 - 0.43 9.1 21.6 0.17 10.5 12.7 1.9 2 1 0 2 2 2 0 Spc7 kinetochore protein ERM PF00769.14 KEG05498.1 - 0.87 9.0 24.2 0.17 11.4 13.7 2.0 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Toxin_52 PF15605.1 KEG05498.1 - 1 9.3 5.0 2.6 7.9 0.4 2.9 2 0 0 2 2 2 0 Putative toxin 52 DUF342 PF03961.8 KEG05498.1 - 1.1 7.5 5.0 2 6.7 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF948 PF06103.6 KEG05498.1 - 1.6 8.6 7.4 1.7 8.5 1.0 2.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.7 KEG05498.1 - 1.9 8.3 6.3 2.6 7.8 2.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) GAS PF13851.1 KEG05498.1 - 1.9 7.6 20.2 0.63 9.1 1.3 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Prefoldin PF02996.12 KEG05498.1 - 2.8 7.6 16.5 0.19 11.3 3.5 3.4 1 1 2 4 4 4 0 Prefoldin subunit TMPIT PF07851.8 KEG05498.1 - 3.9 6.4 10.4 1.6 7.7 5.1 1.6 1 1 1 2 2 2 0 TMPIT-like protein Reo_sigmaC PF04582.7 KEG05498.1 - 4.6 6.3 13.7 0.14 11.2 3.3 2.3 2 0 0 2 2 2 0 Reovirus sigma C capsid protein UPF0242 PF06785.6 KEG05498.1 - 5.1 5.6 11.1 13 4.3 7.7 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) Cluap1 PF10234.4 KEG05498.1 - 5.2 6.1 15.9 0.46 9.6 2.7 2.3 1 1 1 2 2 2 0 Clusterin-associated protein-1 Flagellin_N PF00669.15 KEG05498.1 - 6.1 6.6 17.7 1.6 8.5 0.7 3.6 3 0 0 3 3 3 0 Bacterial flagellin N-terminal helical region APG6 PF04111.7 KEG05498.1 - 6.5 5.6 26.3 5.8 5.8 9.1 2.4 2 1 1 3 3 3 0 Autophagy protein Apg6 TPR_MLP1_2 PF07926.7 KEG05498.1 - 9.6 5.9 27.0 3.9 7.2 16.2 2.3 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein PUB PF09409.5 KEG05499.1 - 5.2e-33 112.6 0.0 8e-18 63.9 0.0 2.3 2 0 0 2 2 2 2 PUB domain SHOCT PF09851.4 KEG05499.1 - 0.00029 20.2 1.6 0.00029 20.2 1.1 2.3 2 0 0 2 2 2 1 Short C-terminal domain ETC_C1_NDUFA5 PF04716.9 KEG05499.1 - 0.0014 18.0 0.3 0.038 13.5 0.1 2.5 2 0 0 2 2 2 1 ETC complex I subunit conserved region FKBP_N PF01346.13 KEG05499.1 - 0.16 12.0 0.9 0.3 11.1 0.6 1.4 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase GldM_N PF12081.3 KEG05500.1 - 0.0072 15.8 1.8 0.0072 15.8 1.3 3.0 3 0 0 3 3 3 1 GldM N-terminal domain PARP_reg PF02877.9 KEG05500.1 - 0.03 13.9 1.4 0.13 11.9 0.4 2.1 2 0 0 2 2 2 0 Poly(ADP-ribose) polymerase, regulatory domain Arch_ATPase PF01637.13 KEG05500.1 - 6 6.4 5.6 1.6 8.4 0.2 2.3 2 1 1 3 3 3 0 Archaeal ATPase Imm35 PF15581.1 KEG05501.1 - 0.29 11.1 2.5 0.35 10.9 0.1 2.5 2 2 0 2 2 2 0 Immunity protein 35 SMN PF06003.7 KEG05502.1 - 0.17 11.0 3.3 0.2 10.7 2.3 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) AMP-binding_C PF13193.1 KEG05505.1 - 0.036 15.0 4.7 0.036 15.0 3.3 2.3 2 1 0 2 2 2 0 AMP-binding enzyme C-terminal domain TFIIA PF03153.8 KEG05509.1 - 4.2 7.1 7.6 5 6.9 5.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 KEG05509.1 - 5.9 5.0 13.2 6.5 4.8 9.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 KEG05509.1 - 8.3 5.7 13.7 10 5.4 9.5 1.0 1 0 0 1 1 1 0 Vta1 like Apo-CIII PF05778.7 KEG05510.1 - 0.3 10.4 2.8 2.1 7.7 0.0 2.7 2 0 0 2 2 2 0 Apolipoprotein CIII (Apo-CIII) Pex19 PF04614.7 KEG05510.1 - 0.35 10.4 9.0 1.7 8.2 6.3 2.1 1 1 0 1 1 1 0 Pex19 protein family Anti-adapt_IraP PF10796.4 KEG05510.1 - 0.69 10.3 5.6 0.82 10.0 0.1 3.0 3 0 0 3 3 3 0 Sigma-S stabilisation anti-adaptor protein E1-E2_ATPase PF00122.15 KEG05511.1 - 5.9e-55 185.7 3.7 7.9e-55 185.3 2.6 1.1 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.21 KEG05511.1 - 5.9e-14 51.2 0.0 1.3e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.21 KEG05511.1 - 0.023 15.0 0.0 0.042 14.2 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF2207 PF09972.4 KEG05511.1 - 0.032 12.8 3.9 0.21 10.1 2.2 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) zf-DHHC PF01529.15 KEG05511.1 - 1.7 8.0 7.2 3.4 7.0 5.0 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase SUR7 PF06687.7 KEG05511.1 - 4.3 6.8 10.4 1.9 8.0 4.9 1.9 2 0 0 2 2 2 0 SUR7/PalI family Dynactin_p62 PF05502.8 KEG05512.1 - 0.16 10.6 4.1 0.19 10.4 2.8 1.1 1 0 0 1 1 1 0 Dynactin p62 family Cytochrom_C_2 PF01322.15 KEG05512.1 - 1.3 9.5 9.8 2 8.9 1.8 2.3 2 0 0 2 2 2 0 Cytochrome C' Adenylsucc_synt PF00709.16 KEG05514.1 - 0.0049 15.5 0.2 0.0049 15.5 0.1 1.9 1 1 0 2 2 2 1 Adenylosuccinate synthetase CortBP2 PF09727.4 KEG05514.1 - 0.041 13.3 9.9 0.12 11.8 6.9 1.9 1 1 0 1 1 1 0 Cortactin-binding protein-2 NABP PF07990.7 KEG05514.1 - 0.046 12.9 1.3 0.072 12.3 0.9 1.3 1 0 0 1 1 1 0 Nucleic acid binding protein NABP DUF972 PF06156.8 KEG05514.1 - 0.19 12.0 7.0 1.1 9.6 0.1 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF972) FliJ PF02050.11 KEG05514.1 - 0.2 11.7 12.8 0.18 11.8 4.0 2.4 2 1 0 2 2 2 0 Flagellar FliJ protein PTS_IIA PF02255.11 KEG05514.1 - 0.77 9.6 12.9 0.072 12.9 2.1 3.1 2 1 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit LRS4 PF10422.4 KEG05514.1 - 0.93 8.7 11.5 4.1 6.6 7.7 2.1 1 1 0 1 1 1 0 Monopolin complex subunit LRS4 EIF_2_alpha PF07541.7 KEG05514.1 - 1.3 8.7 8.2 0.32 10.7 1.5 2.4 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 2 alpha subunit Mucin PF01456.12 KEG05514.1 - 2.1 8.1 11.1 68 3.2 7.7 2.5 1 1 0 1 1 1 0 Mucin-like glycoprotein MIF4G_like_2 PF09090.6 KEG05514.1 - 2.7 7.1 11.8 0.9 8.7 4.6 2.0 1 1 0 2 2 2 0 MIF4G like ETRAMP PF09716.5 KEG05514.1 - 3.6 7.6 6.5 8.6 6.4 4.5 2.0 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) AAA_13 PF13166.1 KEG05514.1 - 6 5.1 17.2 8.3 4.7 11.9 1.2 1 0 0 1 1 1 0 AAA domain DUF3391 PF11871.3 KEG05514.1 - 9.7 6.4 14.9 4.7 7.4 0.3 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) Peptidase_M8 PF01457.11 KEG05516.1 - 7.3e-08 31.2 0.5 1.2e-07 30.5 0.3 1.3 1 0 0 1 1 1 1 Leishmanolysin Pox_Ag35 PF03286.9 KEG05516.1 - 2.2e-06 27.3 0.6 2.2e-06 27.3 0.4 1.2 1 0 0 1 1 1 1 Pox virus Ag35 surface protein Vfa1 PF08432.5 KEG05516.1 - 0.0026 17.8 1.1 0.0038 17.2 0.8 1.2 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 DUF2992 PF11208.3 KEG05516.1 - 0.038 13.8 1.7 0.051 13.4 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) DUF4448 PF14610.1 KEG05516.1 - 0.068 12.6 0.3 0.15 11.5 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4448) Plasmodium_Vir PF05795.6 KEG05516.1 - 0.14 11.2 1.0 0.19 10.9 0.7 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein NPR3 PF03666.8 KEG05516.1 - 0.29 9.6 3.8 0.37 9.2 2.6 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FLO_LFY PF01698.11 KEG05516.1 - 0.42 9.4 3.7 0.47 9.2 2.5 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein PRP21_like_P PF12230.3 KEG05516.1 - 0.66 9.4 7.9 0.92 8.9 5.5 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein Pes-10 PF07149.6 KEG05517.1 - 0.15 10.8 0.4 0.18 10.5 0.3 1.0 1 0 0 1 1 1 0 Pes-10 TRAM_LAG1_CLN8 PF03798.11 KEG05518.1 - 3.7e-07 29.8 10.7 4.8e-07 29.5 7.4 1.1 1 0 0 1 1 1 1 TLC domain ATG16 PF08614.6 KEG05520.1 - 7.4e-08 32.4 21.3 2.8e-06 27.2 4.0 2.4 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Macoilin PF09726.4 KEG05520.1 - 0.00035 19.0 10.1 0.00035 19.0 7.0 1.6 2 0 0 2 2 2 1 Transmembrane protein CENP-Q PF13094.1 KEG05520.1 - 0.0015 18.6 1.0 0.0015 18.6 0.7 2.6 2 1 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit IncA PF04156.9 KEG05520.1 - 0.16 11.5 15.9 0.27 10.7 5.0 2.2 2 0 0 2 2 2 0 IncA protein Nodulin-like PF06813.8 KEG05522.1 - 8.9e-08 31.6 6.9 1e-07 31.5 4.8 1.0 1 0 0 1 1 1 1 Nodulin-like DUF3040 PF11239.3 KEG05522.1 - 0.72 9.9 4.6 15 5.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) ABC2_membrane_4 PF12730.2 KEG05522.1 - 1.2 8.2 15.4 1.8 7.6 10.6 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF3917 PF13055.1 KEG05522.1 - 1.4 9.2 5.2 28 5.0 3.6 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3917) Guanylate_cyc PF00211.15 KEG05528.1 - 8.5e-07 28.5 0.0 1.7e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PEP_mutase PF13714.1 KEG05529.1 - 1.4e-68 230.6 0.9 1.9e-37 128.7 0.1 2.1 1 1 1 2 2 2 2 Phosphoenolpyruvate phosphomutase DUF2529 PF10740.4 KEG05529.1 - 0.063 12.7 0.0 0.12 11.7 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2529) ICL PF00463.16 KEG05529.1 - 0.076 11.2 0.3 0.23 9.6 0.0 1.7 2 0 0 2 2 2 0 Isocitrate lyase family CLN3 PF02487.12 KEG05530.1 - 4.1e-27 95.0 3.6 1.9e-19 69.7 0.2 2.4 2 0 0 2 2 2 2 CLN3 protein TOMM6 PF15184.1 KEG05530.1 - 0.0062 15.8 0.2 5 6.5 0.0 2.7 2 0 0 2 2 2 2 Mitochondrial import receptor subunit TOM6 homolog Nucleoside_tran PF01733.13 KEG05530.1 - 0.1 11.7 0.1 0.1 11.7 0.1 2.6 2 1 1 3 3 3 0 Nucleoside transporter Mod_r PF07200.8 KEG05531.1 - 0.035 14.0 2.7 0.053 13.4 1.9 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF904 PF06005.7 KEG05531.1 - 1.9 8.8 7.8 1.5 9.1 1.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF904) HisKA PF00512.20 KEG05532.1 - 0.099 12.6 0.1 0.32 11.0 0.0 1.8 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain RNase_H2_suC PF08615.6 KEG05533.1 - 7.7e-13 48.4 0.0 9e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) GTP_cyclohydroI PF01227.17 KEG05533.1 - 0.071 12.3 0.1 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 GTP cyclohydrolase I Mucin PF01456.12 KEG05534.1 - 7.6e-11 41.9 29.4 6e-08 32.5 5.6 3.3 3 0 0 3 3 3 2 Mucin-like glycoprotein FH2 PF02181.18 KEG05534.1 - 0.0012 17.8 19.4 0.0019 17.1 1.3 3.1 3 0 0 3 3 3 2 Formin Homology 2 Domain IFP_35_N PF07334.8 KEG05534.1 - 0.016 15.1 0.8 0.046 13.6 0.5 1.8 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus TMF_TATA_bd PF12325.3 KEG05534.1 - 1.6 8.4 23.9 1.1 8.9 0.5 3.6 4 1 0 4 4 4 0 TATA element modulatory factor 1 TATA binding LXG PF04740.7 KEG05534.1 - 1.9 8.2 16.3 0.029 14.1 1.1 3.2 3 1 0 3 3 3 0 LXG domain of WXG superfamily APG6 PF04111.7 KEG05534.1 - 8.1 5.3 26.3 0.074 12.0 2.9 3.1 3 0 0 3 3 3 0 Autophagy protein Apg6 FIST_C PF10442.4 KEG05535.1 - 0.041 13.8 1.7 0.052 13.5 0.3 1.8 1 1 1 2 2 2 0 FIST C domain Ribosomal_L5_C PF00673.16 KEG05535.1 - 0.076 12.7 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 ribosomal L5P family C-terminus I_LWEQ PF01608.12 KEG05535.1 - 0.38 10.6 19.0 0.67 9.8 5.2 2.2 2 0 0 2 2 2 0 I/LWEQ domain FliJ PF02050.11 KEG05535.1 - 0.39 10.7 15.7 4.2 7.4 0.3 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein Borrelia_P83 PF05262.6 KEG05535.1 - 0.89 7.7 20.2 1.4 7.1 14.0 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Mucin PF01456.12 KEG05535.1 - 1.2 8.9 13.1 0.044 13.5 1.2 2.6 1 1 0 2 2 2 0 Mucin-like glycoprotein IFT46_B_C PF12317.3 KEG05535.1 - 3 7.1 6.5 0.65 9.3 1.3 1.9 2 0 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal Aminotran_1_2 PF00155.16 KEG05536.1 - 7e-37 127.2 0.0 8e-37 127.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KEG05536.1 - 9e-06 24.9 0.0 1.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 KEG05536.1 - 0.001 17.4 0.0 0.0013 17.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 KEG05536.1 - 0.0039 16.3 0.0 0.005 16.0 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DUF3619 PF12279.3 KEG05537.1 - 0.03 14.4 0.1 0.045 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) WD40 PF00400.27 KEG05538.1 - 5.2e-22 76.8 16.7 5.2e-06 26.1 0.1 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat TMF_DNA_bd PF12329.3 KEG05539.1 - 0.016 14.9 3.8 0.016 14.9 2.7 7.8 3 3 6 9 9 9 0 TATA element modulatory factor 1 DNA binding Pkinase PF00069.20 KEG05540.1 - 1.4e-61 207.9 0.0 1.7e-61 207.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG05540.1 - 2.9e-25 88.8 0.1 1.1e-24 86.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG05540.1 - 0.00087 18.3 0.0 0.0013 17.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KEG05540.1 - 0.0017 17.4 0.0 0.0029 16.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEG05540.1 - 0.011 15.5 0.0 0.021 14.5 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Reovirus_cap PF00979.12 KEG05541.1 - 0.063 12.2 0.0 0.063 12.2 0.0 1.2 1 0 0 1 1 1 0 Reovirus outer capsid protein, Sigma 3 DUF805 PF05656.9 KEG05541.1 - 0.18 11.6 0.6 0.31 10.8 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF805) Lsr2 PF11774.3 KEG05543.1 - 0.093 12.6 0.5 0.12 12.2 0.3 1.2 1 0 0 1 1 1 0 Lsr2 Peripla_BP_6 PF13458.1 KEG05544.1 - 0.0051 16.2 0.1 0.0078 15.6 0.1 1.3 1 0 0 1 1 1 1 Periplasmic binding protein DUF948 PF06103.6 KEG05545.1 - 0.068 13.0 0.1 0.068 13.0 0.0 2.8 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) AF0941-like PF14591.1 KEG05545.1 - 0.68 9.9 7.1 6.1 6.9 0.5 3.0 2 1 0 2 2 2 0 AF0941-like LXG PF04740.7 KEG05545.1 - 0.75 9.5 15.1 0.14 11.9 3.8 2.9 1 1 2 3 3 3 0 LXG domain of WXG superfamily ISG65-75 PF11727.3 KEG05545.1 - 1.1 8.2 41.8 1.6 7.6 6.9 3.3 1 1 2 3 3 3 0 Invariant surface glycoprotein TPMT PF05724.6 KEG05546.1 - 7.4e-14 51.7 0.1 7.4e-14 51.7 0.1 1.6 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.2 KEG05546.1 - 0.0006 20.3 0.0 0.0013 19.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEG05546.1 - 0.075 12.7 0.0 0.29 10.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain RHSP PF07999.6 KEG05551.1 - 1.1e-34 119.8 0.0 1.3e-34 119.6 0.0 1.0 1 0 0 1 1 1 1 Retrotransposon hot spot protein Glyco_transf_52 PF07922.6 KEG05553.1 - 0.13 11.3 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 52 Propeptide_C1 PF08127.8 KEG05555.1 - 0.064 12.8 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Peptidase family C1 propeptide MtrD PF04207.7 KEG05555.1 - 0.072 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit D GAF PF01590.21 KEG05557.1 - 0.038 14.0 0.1 0.062 13.4 0.1 1.3 1 0 0 1 1 1 0 GAF domain NolV PF06635.7 KEG05559.1 - 0.0088 15.2 1.7 0.0088 15.2 1.2 1.5 1 1 0 1 1 1 1 Nodulation protein NolV Herpes_LMP2 PF07415.6 KEG05559.1 - 2.1 6.8 7.5 3.1 6.2 5.2 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein DUF1664 PF07889.7 KEG05559.1 - 2.8 7.7 7.8 3 7.6 0.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) ATP11 PF06644.6 KEG05561.1 - 5.1e-25 88.4 0.6 6.6e-25 88.1 0.4 1.1 1 0 0 1 1 1 1 ATP11 protein LETM1 PF07766.8 KEG05564.1 - 0.012 14.6 2.1 0.014 14.4 1.2 1.3 1 1 0 1 1 1 0 LETM1-like protein DUF3573 PF12097.3 KEG05564.1 - 0.025 13.2 0.5 0.032 12.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF3450 PF11932.3 KEG05564.1 - 0.065 12.4 1.5 0.09 12.0 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) IFT57 PF10498.4 KEG05564.1 - 0.12 11.0 3.6 0.15 10.7 2.5 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 ERp29 PF07749.7 KEG05564.1 - 0.13 12.8 0.3 0.13 12.8 0.2 2.4 1 1 1 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain DUF1515 PF07439.6 KEG05564.1 - 0.14 11.9 2.0 0.25 11.1 0.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) DUF2580 PF10824.3 KEG05564.1 - 0.81 10.0 7.1 0.87 9.9 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2580) Tropomyosin_1 PF12718.2 KEG05564.1 - 1.4 8.7 10.3 1.8 8.4 6.0 2.0 1 1 0 1 1 1 0 Tropomyosin like Mucin PF01456.12 KEG05564.1 - 1.4 8.7 11.5 2.9 7.6 8.0 1.6 1 1 0 1 1 1 0 Mucin-like glycoprotein DUF948 PF06103.6 KEG05564.1 - 4 7.3 10.6 10 6.0 5.1 2.8 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) RPOL_N PF14700.1 KEG05564.1 - 7.4 5.7 9.8 0.49 9.5 0.2 2.0 1 1 1 2 2 2 0 DNA-directed RNA polymerase N-terminal zf-CCCH PF00642.19 KEG05571.1 - 3.1e-08 33.1 2.3 3.1e-08 33.1 1.6 2.3 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TrbH PF07283.6 KEG05574.1 - 0.079 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Conjugal transfer protein TrbH Mucin PF01456.12 KEG05575.1 - 0.057 13.2 21.5 1.4 8.6 14.9 2.6 1 1 0 1 1 1 0 Mucin-like glycoprotein Tape_meas_lam_C PF09718.5 KEG05575.1 - 4.1 7.3 14.8 0.32 10.9 0.3 4.0 3 2 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Bap31 PF05529.7 KEG05576.1 - 0.016 14.6 0.1 0.021 14.2 0.0 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Rax2 PF12768.2 KEG05578.1 - 0.045 12.9 0.4 0.073 12.2 0.2 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity CWC25 PF12542.3 KEG05578.1 - 2.2 8.7 5.9 8.5 6.9 3.1 2.1 1 1 1 2 2 2 0 Pre-mRNA splicing factor Hexokinase_1 PF00349.16 KEG05579.1 - 9.7e-63 211.2 0.4 1.4e-62 210.6 0.3 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 KEG05579.1 - 2.2e-55 187.5 0.0 3e-55 187.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase PELOTA_1 PF15608.1 KEG05581.1 - 0.41 10.4 8.5 1.7 8.4 2.3 2.3 2 0 0 2 2 2 0 PELOTA RNA binding domain PPR_2 PF13041.1 KEG05582.1 - 3.2e-43 145.4 6.3 1.8e-07 31.0 0.1 9.1 4 2 6 10 10 10 8 PPR repeat family PPR_3 PF13812.1 KEG05582.1 - 8e-35 116.1 11.1 0.011 15.9 0.0 11.9 12 0 0 12 12 12 8 Pentatricopeptide repeat domain PPR PF01535.15 KEG05582.1 - 2.1e-33 111.9 21.1 0.00048 19.9 0.0 11.8 13 1 0 13 13 13 7 PPR repeat PPR_1 PF12854.2 KEG05582.1 - 3.2e-21 74.5 8.6 0.0036 16.7 0.0 9.8 10 0 0 10 10 10 5 PPR repeat ECSIT PF06239.6 KEG05582.1 - 8.2e-07 28.1 0.0 0.44 9.3 0.0 4.3 3 1 1 4 4 4 3 Evolutionarily conserved signalling intermediate in Toll pathway TPR_14 PF13428.1 KEG05582.1 - 0.00073 19.9 11.7 36 5.3 0.2 7.6 4 4 4 9 9 9 0 Tetratricopeptide repeat TPR_12 PF13424.1 KEG05582.1 - 0.0046 16.8 6.5 3.8 7.5 0.1 5.6 4 1 2 6 6 6 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 KEG05582.1 - 0.037 13.8 0.0 0.26 11.0 0.0 2.4 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 Ribosomal_L28e PF01778.12 KEG05585.1 - 3.6e-21 75.7 4.0 3.7e-21 75.6 2.3 1.4 1 1 0 1 1 1 1 Ribosomal L28e protein family ApbA PF02558.11 KEG05585.1 - 0.12 11.8 0.9 0.29 10.5 0.0 2.0 2 1 1 3 3 3 0 Ketopantoate reductase PanE/ApbA Cyclin_N PF00134.18 KEG05586.1 - 0.022 14.3 0.0 0.52 9.8 0.0 2.1 1 1 1 2 2 2 0 Cyclin, N-terminal domain MAP7 PF05672.6 KEG05589.1 - 2.1 7.6 76.1 1.2 8.4 24.5 2.5 1 1 1 2 2 2 0 MAP7 (E-MAP-115) family Pkinase PF00069.20 KEG05591.1 - 1.8e-15 56.8 0.0 7.8e-15 54.7 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG05591.1 - 3.1e-06 26.4 0.0 1.5e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Lzipper-MIP1 PF14389.1 KEG05591.1 - 0.012 15.7 0.8 0.022 14.8 0.5 1.4 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Methyltransf_4 PF02390.12 KEG05592.1 - 0.043 12.8 0.0 0.05 12.6 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase NUDIX PF00293.23 KEG05593.1 - 1.4e-14 53.8 0.1 2.2e-14 53.2 0.1 1.3 1 1 0 1 1 1 1 NUDIX domain DUF1725 PF08333.6 KEG05593.1 - 1.1 8.6 3.5 2.3 7.6 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) Sperm_Ag_HE2 PF05324.8 KEG05594.1 - 8.4 6.3 6.3 41 4.1 3.4 2.3 2 0 0 2 2 2 0 Sperm antigen HE2 DUF2259 PF10016.4 KEG05596.1 - 0.0025 17.5 0.1 5.2 6.7 0.0 3.7 4 0 0 4 4 4 2 Predicted secreted protein (DUF2259) SmpA_OmlA PF04355.8 KEG05596.1 - 0.0041 16.6 0.0 63 3.2 0.0 4.6 5 0 0 5 5 5 0 SmpA / OmlA family CDC37_C PF08564.5 KEG05596.1 - 0.055 13.3 0.2 16 5.4 0.0 3.0 3 0 0 3 3 3 0 Cdc37 C terminal domain Pol_alpha_B_N PF08418.5 KEG05597.1 - 0.47 9.9 6.7 0.57 9.6 4.6 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal ABC_tran_2 PF12848.2 KEG05597.1 - 2.2 8.2 10.5 4.1 7.3 7.3 1.5 1 0 0 1 1 1 0 ABC transporter Mucin PF01456.12 KEG05600.1 - 8.6e-07 28.8 7.9 8.6e-07 28.8 5.5 4.0 1 1 1 2 2 2 1 Mucin-like glycoprotein DEAD PF00270.24 KEG05601.1 - 3.1e-05 23.5 0.0 5.7e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEG05601.1 - 3.6e-05 23.5 0.1 0.0002 21.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Acetyltransf_1 PF00583.19 KEG05602.1 - 1.2e-14 54.0 0.1 1.5e-14 53.7 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEG05602.1 - 5.9e-10 39.1 0.0 6.8e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KEG05602.1 - 4.5e-09 36.4 0.1 5e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEG05602.1 - 3.7e-06 26.6 0.0 4.7e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 KEG05602.1 - 9.4e-06 25.5 0.0 1.2e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KEG05602.1 - 0.00034 20.4 0.1 0.00064 19.5 0.1 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 KEG05602.1 - 0.0018 18.2 0.0 0.0023 17.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KEG05602.1 - 0.008 16.1 0.0 0.0089 15.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.1 KEG05602.1 - 0.013 14.8 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Acetyltransf_3 PF13302.1 KEG05602.1 - 0.018 15.1 0.0 0.022 14.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 KEG05602.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Flu_NS2 PF00601.14 KEG05603.1 - 0.019 15.1 0.9 0.034 14.3 0.3 1.6 1 1 0 1 1 1 0 Influenza non-structural protein (NS2) DUF3606 PF12244.3 KEG05603.1 - 0.021 14.4 1.9 0.062 12.9 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) APG6 PF04111.7 KEG05603.1 - 0.078 12.0 5.9 0.12 11.3 4.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 FH2 PF02181.18 KEG05603.1 - 0.099 11.5 2.7 0.13 11.0 1.9 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain V_ATPase_I PF01496.14 KEG05603.1 - 0.16 9.7 4.1 0.21 9.3 2.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ubiquitin_3 PF14836.1 KEG05603.1 - 0.23 11.1 2.1 0.32 10.6 0.1 1.9 1 1 1 2 2 2 0 Ubiquitin-like domain HAUS6_N PF14661.1 KEG05603.1 - 0.46 9.7 6.8 0.8 9.0 4.7 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF3450 PF11932.3 KEG05603.1 - 1.3 8.2 11.2 0.083 12.1 4.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Syntaxin PF00804.20 KEG05603.1 - 1.6 8.9 11.5 0.29 11.3 4.7 2.2 2 1 0 2 2 2 0 Syntaxin Borrelia_P83 PF05262.6 KEG05604.1 - 0.18 10.0 27.4 0.22 9.7 19.0 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein TEX15 PF15326.1 KEG05604.1 - 2.7 7.5 10.7 3.5 7.1 7.4 1.0 1 0 0 1 1 1 0 Testis expressed sequence 15 DUF572 PF04502.8 KEG05604.1 - 3.9 6.5 25.6 4.5 6.3 17.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) MIP-T3 PF10243.4 KEG05604.1 - 5.2 5.4 43.0 6.5 5.1 29.8 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 FAM60A PF15396.1 KEG05604.1 - 9.2 5.9 14.4 11 5.6 9.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A HC2 PF07382.6 KEG05605.1 - 0.52 10.1 36.6 0.67 9.7 25.3 1.1 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Peptidase_M8 PF01457.11 KEG05606.1 - 5.2e-102 341.8 5.9 2.1e-53 181.4 0.2 2.0 1 1 1 2 2 2 2 Leishmanolysin Reprolysin_5 PF13688.1 KEG05606.1 - 0.0047 16.8 0.0 0.0084 16.0 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M57 PF12388.3 KEG05606.1 - 0.016 14.5 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase CENP-F_leu_zip PF10473.4 KEG05608.1 - 0.0026 17.6 78.6 0.017 15.0 6.5 4.8 3 2 2 5 5 5 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cortex-I_coil PF09304.5 KEG05608.1 - 0.01 15.8 2.1 0.01 15.8 1.4 6.6 3 3 3 6 6 6 0 Cortexillin I, coiled coil DUF1664 PF07889.7 KEG05608.1 - 0.011 15.5 21.1 0.37 10.6 0.2 5.6 3 3 2 5 5 5 0 Protein of unknown function (DUF1664) DUF2009 PF09418.5 KEG05608.1 - 0.55 8.9 10.9 0.1 11.3 3.6 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2009) Reo_sigmaC PF04582.7 KEG05608.1 - 0.56 9.3 18.6 1 8.5 0.8 3.1 3 0 0 3 3 3 0 Reovirus sigma C capsid protein DUF1103 PF06513.6 KEG05608.1 - 5.6 6.2 14.7 0.048 13.0 1.9 2.8 3 0 0 3 3 3 0 Repeat of unknown function (DUF1103) Peripla_BP_6 PF13458.1 KEG05611.1 - 5.5e-10 39.1 0.0 9.7e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein RHSP PF07999.6 KEG05612.1 - 5.4e-98 328.4 0.2 9.5e-98 327.6 0.1 1.4 1 0 0 1 1 1 1 Retrotransposon hot spot protein Macro_2 PF14519.1 KEG05612.1 - 0.035 13.2 0.0 0.063 12.3 0.0 1.3 1 0 0 1 1 1 0 Macro-like domain EF-hand_7 PF13499.1 KEG05615.1 - 3.6e-11 43.0 0.1 1.2e-06 28.5 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KEG05615.1 - 1.2e-08 34.4 0.0 0.00078 19.0 0.0 3.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 KEG05615.1 - 1.8e-08 33.5 0.3 0.052 13.4 0.0 3.9 3 1 1 4 4 4 2 EF-hand domain EF-hand_9 PF14658.1 KEG05615.1 - 3e-08 33.4 0.0 0.0032 17.3 0.0 2.9 2 1 1 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 KEG05615.1 - 1.4e-06 27.1 0.0 0.27 10.6 0.0 3.9 4 0 0 4 4 4 2 EF hand DUF2087 PF09860.4 KEG05615.1 - 0.00043 19.9 0.0 1.1 9.0 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2087) DUF3349 PF11829.3 KEG05615.1 - 0.048 14.0 0.4 0.46 10.9 0.1 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) RNA_pol_Rpb4 PF03874.11 KEG05615.1 - 0.12 12.3 0.1 10 6.1 0.1 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb4 UPF0154 PF03672.8 KEG05615.1 - 0.14 11.8 0.0 22 4.7 0.0 2.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) EF-hand_5 PF13202.1 KEG05615.1 - 0.16 11.4 0.5 4.7 6.7 0.0 2.7 3 0 0 3 3 3 0 EF hand Ribosomal_60s PF00428.14 KEG05616.1 - 1.2 9.5 21.5 2.3 8.6 14.9 1.5 1 1 0 1 1 1 0 60s Acidic ribosomal protein CENP-T PF15511.1 KEG05616.1 - 2.2 7.4 10.8 2.7 7.1 7.5 1.2 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T DUF1016 PF06250.6 KEG05617.1 - 0.011 14.6 0.5 0.017 14.1 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1016) KOW PF00467.24 KEG05617.1 - 0.012 15.3 1.1 0.012 15.3 0.8 2.2 2 1 1 3 3 3 0 KOW motif Lebercilin PF15619.1 KEG05619.1 - 1.9 7.8 7.5 0.13 11.6 1.8 1.5 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease PXA PF02194.10 KEG05619.1 - 9.8 5.6 6.5 32 4.0 4.5 1.9 1 1 0 1 1 1 0 PXA domain Motile_Sperm PF00635.21 KEG05620.1 - 6e-13 48.3 0.0 1e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain PapD-like PF14874.1 KEG05620.1 - 0.0059 16.5 0.2 0.012 15.5 0.1 1.4 1 0 0 1 1 1 1 Flagellar-associated PapD-like Peripla_BP_6 PF13458.1 KEG05624.1 - 0.00038 19.9 0.5 0.0019 17.6 0.3 2.0 1 1 0 1 1 1 1 Periplasmic binding protein DUF2976 PF11190.3 KEG05624.1 - 0.11 12.0 0.0 0.53 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) cNMP_binding PF00027.24 KEG05626.1 - 1.1e-17 63.6 0.0 1.6e-07 31.0 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Bromodomain PF00439.20 KEG05627.1 - 5.9e-05 22.9 0.0 7.2e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Bromodomain Barwin PF00967.12 KEG05627.1 - 0.043 13.5 0.0 0.064 12.9 0.0 1.2 1 0 0 1 1 1 0 Barwin family Herpes_gI PF01688.12 KEG05629.1 - 0.072 12.2 0.7 0.079 12.0 0.5 1.3 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein I RunxI PF08504.6 KEG05629.1 - 0.37 11.2 7.3 0.74 10.2 1.3 2.0 1 1 1 2 2 2 0 Runx inhibition domain EMP24_GP25L PF01105.19 KEG05631.1 - 0.00078 19.2 3.0 0.021 14.5 2.1 2.1 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Chibby PF14645.1 KEG05631.1 - 0.035 13.9 4.2 0.032 14.1 1.9 1.7 2 0 0 2 2 2 0 Chibby family Poty_PP PF08440.5 KEG05631.1 - 0.072 12.1 3.8 0.12 11.4 2.6 1.4 1 0 0 1 1 1 0 Potyviridae polyprotein DUF948 PF06103.6 KEG05631.1 - 0.22 11.4 0.9 0.36 10.7 0.6 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF904 PF06005.7 KEG05631.1 - 0.31 11.3 9.3 0.82 10.0 3.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF904) bZIP_1 PF00170.16 KEG05631.1 - 2.3 8.2 6.5 0.65 9.9 1.5 2.1 2 0 0 2 2 2 0 bZIP transcription factor DivIC PF04977.10 KEG05631.1 - 3.2 7.2 8.9 0.41 10.1 2.9 1.8 1 1 1 2 2 2 0 Septum formation initiator YlqD PF11068.3 KEG05631.1 - 7.2 6.6 12.5 12 5.9 8.0 1.8 2 1 0 2 2 2 0 YlqD protein DUF1237 PF06824.6 KEG05632.1 - 3.9e-33 114.6 0.0 4.6e-33 114.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) Hydrolase_3 PF08282.7 KEG05633.1 - 9.6e-24 84.3 0.0 1e-23 84.2 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEG05633.1 - 6.8e-05 23.1 0.0 0.027 14.6 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KEG05633.1 - 0.00025 21.5 0.0 0.00026 21.4 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 KEG05633.1 - 0.00072 19.4 0.0 0.0018 18.1 0.0 1.8 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase S6PP PF05116.8 KEG05633.1 - 0.0031 16.8 0.0 0.0043 16.4 0.0 1.2 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase HAD_2 PF13419.1 KEG05633.1 - 0.029 14.5 0.1 0.6 10.3 0.0 2.5 1 1 2 3 3 3 0 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KEG05634.1 - 9.5e-29 100.7 2.9 1.3e-15 57.6 0.0 2.0 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEG05634.1 - 5.7e-06 26.6 1.1 0.051 13.7 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.8 KEG05634.1 - 2.9e-05 23.4 0.1 0.035 13.4 0.0 2.0 1 1 1 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 KEG05634.1 - 3.6e-05 24.2 6.5 0.0068 16.8 0.3 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase UQ_con PF00179.21 KEG05635.1 - 3.5e-22 78.3 0.0 4.2e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KEG05635.1 - 0.038 13.8 0.0 0.048 13.5 0.0 1.2 1 0 0 1 1 1 0 RWD domain DUF452 PF04301.8 KEG05635.1 - 0.092 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF452) Peripla_BP_6 PF13458.1 KEG05636.1 - 4.7e-10 39.3 0.1 3.5e-09 36.4 0.0 1.9 2 0 0 2 2 2 1 Periplasmic binding protein DUF592 PF04574.8 KEG05636.1 - 0.12 11.9 0.0 0.32 10.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF592) Amidase_5 PF05382.8 KEG05638.1 - 0.02 14.5 0.0 0.04 13.5 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage peptidoglycan hydrolase TMCO5 PF14992.1 KEG05638.1 - 0.17 10.9 12.7 0.042 12.9 0.7 2.2 2 0 0 2 2 2 0 TMCO5 family CLTH PF10607.4 KEG05638.1 - 0.21 11.2 1.5 6 6.5 0.0 2.8 1 1 1 2 2 2 0 CTLH/CRA C-terminal to LisH motif domain Filament PF00038.16 KEG05638.1 - 0.29 10.5 26.0 0.097 12.1 7.1 2.8 2 1 1 3 3 3 0 Intermediate filament protein DUF569 PF04601.8 KEG05639.1 - 0.0099 15.3 0.0 0.013 14.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF569) zf-Di19 PF05605.7 KEG05641.1 - 0.026 14.6 0.2 0.088 12.9 0.2 1.9 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-ISL3 PF14690.1 KEG05641.1 - 0.063 13.3 1.3 0.17 11.9 0.9 1.8 1 1 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-H2C2_5 PF13909.1 KEG05641.1 - 1.4 9.3 6.0 2.3 8.5 0.6 3.2 4 0 0 4 4 4 0 C2H2-type zinc-finger domain RNase_H PF00075.19 KEG05642.1 - 9.3e-09 35.7 0.0 1.1e-08 35.5 0.0 1.0 1 0 0 1 1 1 1 RNase H DUF1088 PF06469.6 KEG05643.1 - 0.019 14.3 0.1 0.032 13.6 0.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1088) Dpy-30 PF05186.8 KEG05644.1 - 0.0026 17.1 0.0 0.0041 16.5 0.0 1.3 1 0 0 1 1 1 1 Dpy-30 motif SBP_bac_11 PF13531.1 KEG05644.1 - 0.0069 16.0 2.3 0.011 15.3 1.6 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SPOC PF07744.8 KEG05644.1 - 0.12 12.8 3.1 0.19 12.1 2.1 1.2 1 0 0 1 1 1 0 SPOC domain DUF4557 PF15101.1 KEG05644.1 - 0.96 9.2 6.6 1.2 8.9 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Hid1 PF12722.2 KEG05646.1 - 2.2 5.8 6.4 2.8 5.5 4.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein M20_dimer PF07687.9 KEG05648.1 - 7.3e-21 74.0 0.0 1.3e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 KEG05648.1 - 4.5e-05 23.0 0.0 4.8e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Mucin PF01456.12 KEG05649.1 - 8.2 6.1 29.6 0.53 10.0 5.6 2.8 2 1 0 2 2 2 0 Mucin-like glycoprotein Toprim PF01751.17 KEG05651.1 - 0.092 12.7 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Toprim domain Cap_synth_GfcB PF11102.3 KEG05652.1 - 0.082 12.4 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Group 4 capsule polysaccharide formation lipoprotein gfcB CcmB PF03379.8 KEG05653.1 - 0.1 11.7 0.4 0.14 11.3 0.3 1.1 1 0 0 1 1 1 0 CcmB protein Mucin PF01456.12 KEG05654.1 - 0.0022 17.7 28.3 0.0022 17.7 19.6 3.9 2 2 0 2 2 2 1 Mucin-like glycoprotein Hid1 PF12722.2 KEG05655.1 - 0.095 10.3 6.9 0.13 9.8 4.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Peptidase_M8 PF01457.11 KEG05656.1 - 9.4e-28 96.8 0.1 1.1e-27 96.6 0.1 1.0 1 0 0 1 1 1 1 Leishmanolysin CCT_2 PF09425.5 KEG05660.1 - 1 8.9 5.9 3.9 7.1 4.1 1.9 1 1 0 1 1 1 0 Divergent CCT motif Mucin PF01456.12 KEG05661.1 - 1.1e-05 25.2 1.5 0.0014 18.3 0.1 2.4 2 0 0 2 2 2 2 Mucin-like glycoprotein Phage_GPL PF05926.6 KEG05661.1 - 0.053 13.3 0.7 0.13 12.1 0.5 1.6 1 0 0 1 1 1 0 Phage head completion protein (GPL) MxiH PF09392.5 KEG05661.1 - 0.056 14.0 1.1 0.11 13.1 0.7 1.5 1 0 0 1 1 1 0 Type III secretion needle MxiH like Collagen PF01391.13 KEG05664.1 - 0.014 14.9 9.0 0.014 14.9 6.3 3.8 3 0 0 3 3 3 0 Collagen triple helix repeat (20 copies) CAP_N PF01213.14 KEG05667.1 - 0.0047 16.2 4.3 0.0047 16.2 2.9 2.4 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) N terminal ABC_ATPase PF09818.4 KEG05668.1 - 3.6e-124 414.7 0.0 4.8e-124 414.3 0.0 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class PAC2 PF09754.4 KEG05668.1 - 0.015 15.1 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 PAC2 family AAA_23 PF13476.1 KEG05668.1 - 0.02 15.2 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KEG05668.1 - 0.045 13.2 0.0 0.13 11.6 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_25 PF13481.1 KEG05668.1 - 0.046 13.1 0.3 0.14 11.5 0.2 1.9 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KEG05668.1 - 0.059 13.6 0.1 3.3 8.0 0.1 2.4 1 1 0 1 1 1 0 ABC transporter Candida_ALS PF05792.8 KEG05670.1 - 1.3 9.1 5.1 3.3 7.9 0.2 2.5 2 0 0 2 2 2 0 Candida agglutinin-like (ALS) LRR_4 PF12799.2 KEG05672.1 - 7.2e-22 76.5 0.9 0.0018 17.8 0.0 6.8 5 1 3 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG05672.1 - 2.4e-19 68.8 6.0 0.00063 19.4 0.2 5.5 4 1 1 5 5 5 5 Leucine rich repeat LRR_6 PF13516.1 KEG05672.1 - 3.8e-16 57.3 11.5 0.0097 15.8 0.0 9.1 8 1 2 10 10 10 6 Leucine Rich repeat LRR_1 PF00560.28 KEG05672.1 - 1.3e-08 33.6 14.2 1.5 9.1 0.0 9.5 9 3 1 10 10 10 2 Leucine Rich Repeat LRR_7 PF13504.1 KEG05672.1 - 4.6e-07 28.9 22.1 7.7 7.2 0.0 10.0 10 1 0 10 10 10 2 Leucine rich repeat Mito_carr PF00153.22 KEG05673.1 - 3.8e-61 202.8 1.7 9.1e-22 76.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-CDGSH PF09360.5 KEG05674.1 - 4.5e-19 67.9 7.0 2.9e-15 55.8 0.6 2.9 3 0 0 3 3 3 2 Iron-binding zinc finger CDGSH type PCI PF01399.22 KEG05675.1 - 5.8e-05 23.3 0.1 0.00039 20.6 0.3 2.2 2 0 0 2 2 2 1 PCI domain TPR_14 PF13428.1 KEG05677.1 - 0.11 13.2 0.7 0.18 12.5 0.5 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.1 KEG05677.1 - 0.12 12.3 2.3 0.21 11.5 1.6 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat HTH_12 PF08461.5 KEG05677.1 - 4 7.2 6.0 8.9 6.1 0.4 2.1 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain IF-2B PF01008.12 KEG05678.1 - 1.2e-67 227.9 0.3 1.3e-67 227.7 0.2 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family NTP_transf_3 PF12804.2 KEG05678.1 - 0.69 9.9 3.7 0.72 9.9 0.6 2.1 1 1 0 2 2 2 0 MobA-like NTP transferase domain DUF3639 PF12341.3 KEG05679.1 - 6.2e-06 26.1 1.8 6.2e-06 26.1 1.2 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3639) Joubert PF15392.1 KEG05680.1 - 0.047 12.9 0.1 0.073 12.2 0.0 1.2 1 0 0 1 1 1 0 Joubert syndrome-associated vATP-synt_AC39 PF01992.11 KEG05682.1 - 5.1e-64 216.5 0.0 6.4e-64 216.2 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Rifin_STEVOR PF02009.11 KEG05684.1 - 0.0068 16.0 0.0 0.0076 15.9 0.0 1.1 1 0 0 1 1 1 1 Rifin/stevor family P12 PF12669.2 KEG05684.1 - 0.0087 16.2 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 1 Virus attachment protein p12 family DUF1191 PF06697.7 KEG05684.1 - 0.029 13.2 0.1 0.042 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) EphA2_TM PF14575.1 KEG05684.1 - 0.065 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain IncA PF04156.9 KEG05684.1 - 0.082 12.4 0.0 0.096 12.2 0.0 1.2 1 0 0 1 1 1 0 IncA protein DUF3619 PF12279.3 KEG05685.1 - 2.2 8.3 6.4 10 6.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) Pkinase PF00069.20 KEG05689.1 - 6.5e-33 113.9 0.0 7.2e-33 113.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG05689.1 - 1.1e-13 50.8 0.0 1.4e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG05689.1 - 0.0016 17.4 0.0 0.0019 17.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like ArfGap PF01412.13 KEG05690.1 - 0.041 13.6 0.5 0.048 13.4 0.4 1.1 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf Ribosomal_S7 PF00177.16 KEG05690.1 - 0.088 12.3 0.2 0.12 11.9 0.2 1.2 1 0 0 1 1 1 0 Ribosomal protein S7p/S5e Ribosomal_L19e PF01280.15 KEG05691.1 - 2.2e-61 205.9 14.8 2.2e-61 205.9 10.3 2.1 1 1 1 2 2 2 1 Ribosomal protein L19e DUF2202 PF09968.4 KEG05691.1 - 0.011 15.3 1.3 0.018 14.7 0.9 1.3 1 0 0 1 1 1 0 Uncharacterized protein domain (DUF2202) Macoilin PF09726.4 KEG05691.1 - 0.46 8.6 17.1 0.49 8.6 11.9 1.2 1 0 0 1 1 1 0 Transmembrane protein Het-C PF07217.6 KEG05691.1 - 1.3 7.1 5.4 1.9 6.6 3.8 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C OmpH PF03938.9 KEG05691.1 - 8.9 6.2 18.5 13 5.7 12.8 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Penicil_amidase PF01804.13 KEG05692.1 - 7.1e-06 25.3 0.1 7.8e-06 25.2 0.0 1.0 1 0 0 1 1 1 1 Penicillin amidase CBM_15 PF03426.9 KEG05693.1 - 0.033 13.5 0.1 0.038 13.3 0.1 1.2 1 0 0 1 1 1 0 Carbohydrate binding domain (family 15) DUF3995 PF13160.1 KEG05693.1 - 0.099 12.6 1.9 0.075 13.0 0.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3995) Med3 PF11593.3 KEG05695.1 - 2.2 7.4 11.2 2.4 7.2 7.8 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal KAAG1 PF15354.1 KEG05696.1 - 0.76 10.1 3.2 0.53 10.6 0.3 1.9 1 1 1 2 2 2 0 Kidney-associated antigen 1 CAF-1_p150 PF11600.3 KEG05697.1 - 0.046 13.0 56.6 0.076 12.3 39.3 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Peripla_BP_6 PF13458.1 KEG05699.1 - 0.093 12.0 2.9 0.11 11.8 0.7 1.8 1 1 1 2 2 2 0 Periplasmic binding protein ABC_tran PF00005.22 KEG05700.1 - 0.1 12.8 0.6 3 8.1 0.1 2.4 2 1 1 3 3 3 0 ABC transporter DUF898 PF05987.8 KEG05702.1 - 0.029 13.2 2.1 0.038 12.8 1.5 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF3353 PF11833.3 KEG05702.1 - 4.7 6.6 5.5 6.1 6.2 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) Polysacc_synt_3 PF13440.1 KEG05702.1 - 4.7 6.5 8.4 4.1 6.8 4.7 1.6 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein EMG1 PF03587.9 KEG05704.1 - 4.5e-72 241.5 0.0 5.6e-72 241.2 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase WEMBL PF05701.6 KEG05705.1 - 0.021 13.3 2.2 0.021 13.2 1.5 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Tim44 PF04280.10 KEG05705.1 - 0.025 14.5 0.2 0.029 14.3 0.2 1.2 1 0 0 1 1 1 0 Tim44-like domain DUF501 PF04417.7 KEG05705.1 - 0.099 12.4 0.9 0.11 12.2 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF501) DDE_Tnp_1_6 PF13751.1 KEG05705.1 - 0.11 12.4 0.5 0.14 12.1 0.3 1.3 1 0 0 1 1 1 0 Transposase DDE domain TerB-C PF15615.1 KEG05705.1 - 0.13 12.4 2.7 0.17 12.1 1.9 1.1 1 0 0 1 1 1 0 TerB-C domain Uds1 PF15456.1 KEG05705.1 - 0.49 10.3 4.3 0.54 10.2 2.2 1.5 1 1 0 1 1 1 0 Up-regulated During Septation HrpB7 PF09486.5 KEG05705.1 - 0.67 9.8 9.2 0.56 10.1 5.6 1.4 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Pox_A_type_inc PF04508.7 KEG05705.1 - 1.7 8.6 0.0 1.7 8.6 0.0 3.6 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Mucin PF01456.12 KEG05707.1 - 0.011 15.5 4.6 0.016 14.9 3.2 1.4 1 1 0 1 1 1 0 Mucin-like glycoprotein Hid1 PF12722.2 KEG05707.1 - 1.1 6.8 7.9 1.2 6.6 5.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2413 PF10310.4 KEG05707.1 - 1.4 7.6 12.8 1.6 7.4 8.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Ndc1_Nup PF09531.5 KEG05707.1 - 1.9 6.7 5.8 2 6.7 4.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DHHW PF14286.1 KEG05707.1 - 2 7.6 4.9 2.2 7.5 3.4 1.1 1 0 0 1 1 1 0 DHHW protein CENP-F_leu_zip PF10473.4 KEG05708.1 - 0.00087 19.1 5.9 0.0056 16.5 4.0 2.0 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.10 KEG05708.1 - 0.0016 17.9 2.8 0.14 11.6 0.6 2.2 2 0 0 2 2 2 1 Septum formation initiator CCDC144C PF14915.1 KEG05708.1 - 0.0031 16.4 2.4 0.0037 16.2 1.7 1.1 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region APG6 PF04111.7 KEG05708.1 - 0.0036 16.4 1.2 0.0043 16.1 0.9 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 Rab5-bind PF09311.6 KEG05708.1 - 0.0096 15.8 3.2 0.49 10.2 0.5 2.1 1 1 1 2 2 2 2 Rabaptin-like protein TPR_MLP1_2 PF07926.7 KEG05708.1 - 0.018 14.7 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4482 PF14818.1 KEG05708.1 - 0.021 15.4 0.2 0.031 14.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) Prefoldin_3 PF13758.1 KEG05708.1 - 0.022 14.5 0.2 0.21 11.3 0.0 2.2 1 1 1 2 2 2 0 Prefoldin subunit ERM PF00769.14 KEG05708.1 - 0.03 13.8 1.2 0.036 13.5 0.9 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF948 PF06103.6 KEG05708.1 - 0.042 13.6 0.5 1.7 8.5 0.2 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Rsa3 PF14615.1 KEG05708.1 - 0.049 12.9 0.2 0.11 11.8 0.2 1.6 1 0 0 1 1 1 0 Ribosome-assembly protein 3 Reo_sigmaC PF04582.7 KEG05708.1 - 0.05 12.7 0.4 0.054 12.6 0.2 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein IncA PF04156.9 KEG05708.1 - 0.052 13.1 5.5 0.1 12.2 3.8 1.4 1 1 0 1 1 1 0 IncA protein Prefoldin PF02996.12 KEG05708.1 - 0.058 13.0 1.9 2.3 7.8 0.2 2.2 1 1 1 2 2 2 0 Prefoldin subunit TMF_TATA_bd PF12325.3 KEG05708.1 - 0.061 13.0 2.1 0.076 12.7 0.9 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding PuR_N PF09182.5 KEG05708.1 - 0.068 12.7 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal CENP-F_N PF10481.4 KEG05708.1 - 0.072 12.4 0.3 0.095 12.0 0.2 1.1 1 0 0 1 1 1 0 Cenp-F N-terminal domain ATG16 PF08614.6 KEG05708.1 - 0.073 12.8 3.5 0.11 12.2 2.4 1.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) RP-C PF03428.8 KEG05708.1 - 0.073 12.5 0.1 0.094 12.1 0.1 1.2 1 0 0 1 1 1 0 Replication protein C N-terminal domain Snapin_Pallidin PF14712.1 KEG05708.1 - 0.078 13.3 1.5 0.47 10.7 0.3 2.3 1 1 1 2 2 2 0 Snapin/Pallidin DUF1664 PF07889.7 KEG05708.1 - 0.097 12.4 0.8 0.85 9.4 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.3 KEG05708.1 - 0.11 12.3 6.8 1.3 8.9 1.5 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Cortex-I_coil PF09304.5 KEG05708.1 - 0.12 12.4 5.0 1.4 9.0 3.5 2.1 1 1 0 1 1 1 0 Cortexillin I, coiled coil Herpes_U30 PF04523.8 KEG05708.1 - 0.12 9.7 0.1 0.13 9.7 0.1 1.1 1 0 0 1 1 1 0 Herpes virus tegument protein U30 DUF4201 PF13870.1 KEG05708.1 - 0.15 11.4 2.2 0.2 11.0 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) MutS_IV PF05190.13 KEG05708.1 - 0.15 12.2 0.9 1.1 9.4 0.4 2.2 1 1 1 2 2 2 0 MutS family domain IV DUF904 PF06005.7 KEG05708.1 - 0.15 12.3 3.8 0.18 12.0 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Prefoldin_2 PF01920.15 KEG05708.1 - 0.17 11.6 4.2 0.92 9.3 0.9 2.2 1 1 1 2 2 2 0 Prefoldin subunit Tektin PF03148.9 KEG05708.1 - 0.24 9.9 2.9 3 6.2 0.6 2.0 1 1 1 2 2 2 0 Tektin family DUF4140 PF13600.1 KEG05708.1 - 0.38 11.2 3.8 0.98 9.9 1.2 2.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) NTR2 PF15458.1 KEG05708.1 - 0.41 9.8 4.3 5 6.2 1.2 2.0 1 1 1 2 2 2 0 Nineteen complex-related protein 2 Med21 PF11221.3 KEG05708.1 - 0.58 10.1 4.3 1.1 9.2 1.1 2.0 1 1 1 2 2 2 0 Subunit 21 of Mediator complex HALZ PF02183.13 KEG05708.1 - 1.8 8.3 9.2 3.6 7.3 3.2 2.9 2 1 0 2 2 2 0 Homeobox associated leucine zipper Kinesin PF00225.18 KEG05709.1 - 3.1e-27 95.1 0.0 3.9e-27 94.8 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Pyocin_S PF06958.7 KEG05709.1 - 0.062 13.6 0.3 0.081 13.2 0.2 1.2 1 0 0 1 1 1 0 S-type Pyocin Acetyltransf_1 PF00583.19 KEG05710.1 - 1.2e-14 54.0 0.0 2e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KEG05710.1 - 6.4e-07 29.0 0.1 1.8e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_7 PF13508.1 KEG05710.1 - 9.5e-05 22.4 0.7 0.00016 21.7 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KEG05710.1 - 0.0041 16.9 0.1 0.0087 15.9 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KEG05710.1 - 0.017 15.2 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RRM_5 PF13893.1 KEG05710.1 - 0.018 14.8 0.0 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GNAT_acetyltr_2 PF13718.1 KEG05710.1 - 0.088 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 CRPA PF05745.6 KEG05711.1 - 0.023 14.5 0.0 0.028 14.2 0.0 1.1 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Tyr_Deacylase PF02580.11 KEG05713.1 - 8.9e-42 142.4 0.0 9.9e-42 142.3 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase FliD_C PF07195.7 KEG05715.1 - 0.0007 18.9 5.1 0.002 17.4 0.1 2.4 2 0 0 2 2 2 1 Flagellar hook-associated protein 2 C-terminus DUF641 PF04859.7 KEG05715.1 - 0.0037 17.0 4.3 0.0037 17.0 3.0 3.6 3 1 1 4 4 4 1 Plant protein of unknown function (DUF641) Med9 PF07544.8 KEG05715.1 - 0.11 12.2 0.2 0.11 12.2 0.2 3.9 3 2 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 V_ATPase_I PF01496.14 KEG05715.1 - 0.79 7.4 7.3 0.76 7.5 1.8 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Fmp27_WPPW PF10359.4 KEG05715.1 - 1.3 7.3 9.7 2.4 6.4 2.6 2.3 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain BLOC1_2 PF10046.4 KEG05715.1 - 1.8 8.7 8.4 1.3 9.2 0.1 3.2 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TACC PF05010.9 KEG05715.1 - 5.4 6.7 20.6 1.2 8.8 2.7 2.5 2 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) Aa_trans PF01490.13 KEG05717.1 - 7.2e-16 57.6 2.1 8.5e-16 57.4 1.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KEG05717.1 - 6e-08 31.9 3.0 7e-08 31.6 2.1 1.0 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family LtrA PF06772.6 KEG05718.1 - 0.6 8.9 2.7 0.27 10.1 0.5 1.4 1 1 0 1 1 1 0 Bacterial low temperature requirement A protein (LtrA) Mucin PF01456.12 KEG05719.1 - 3.3e-08 33.3 7.4 3.3e-08 33.3 5.1 4.0 2 1 1 3 3 3 2 Mucin-like glycoprotein Flagellin_C PF00700.16 KEG05719.1 - 0.96 9.6 6.4 0.71 10.0 0.1 3.1 3 0 0 3 3 3 0 Bacterial flagellin C-terminal helical region IF-2B PF01008.12 KEG05720.1 - 1.4e-32 112.8 0.1 3.8e-32 111.4 0.1 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family Glyco_transf_10 PF00852.14 KEG05722.1 - 4.5e-24 84.6 0.2 6e-19 67.8 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase family 10 (fucosyltransferase) DEAD PF00270.24 KEG05723.1 - 1.1e-42 145.3 0.3 1.6e-42 144.8 0.2 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEG05723.1 - 5.9e-25 86.9 0.3 1.1e-24 86.0 0.2 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KEG05723.1 - 0.046 13.8 0.4 0.13 12.4 0.3 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 KEG05723.1 - 0.091 12.9 0.5 0.53 10.4 0.4 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 KEG05723.1 - 0.13 11.4 0.9 7 5.8 0.2 2.4 1 1 1 2 2 2 0 PhoH-like protein DUF4355 PF14265.1 KEG05726.1 - 0.18 11.7 0.0 0.18 11.7 0.0 4.7 2 2 2 4 4 4 0 Domain of unknown function (DUF4355) Peptidase_S49_N PF08496.5 KEG05727.1 - 2.6 7.7 9.0 2.5 7.8 6.3 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal BAF1_ABF1 PF04684.8 KEG05727.1 - 4.9 5.8 30.1 5.6 5.6 20.8 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PBP1_TM PF14812.1 KEG05727.1 - 7.3 6.9 9.0 8.5 6.7 6.2 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Spore_coat_CotO PF14153.1 KEG05727.1 - 9.3 5.6 17.2 9.6 5.6 11.9 1.0 1 0 0 1 1 1 0 Spore coat protein CotO DUF387 PF04079.11 KEG05731.1 - 0.064 12.6 0.0 0.083 12.2 0.0 1.1 1 0 0 1 1 1 0 Putative transcriptional regulators (Ypuh-like) SpoIIIAH PF12685.2 KEG05734.1 - 0.00019 20.9 0.0 0.00027 20.4 0.0 1.2 1 0 0 1 1 1 1 SpoIIIAH-like protein FAM101 PF15068.1 KEG05734.1 - 0.0073 15.7 2.0 0.011 15.2 1.4 1.3 1 0 0 1 1 1 1 FAM101 family EphA2_TM PF14575.1 KEG05734.1 - 0.0076 16.6 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF1191 PF06697.7 KEG05734.1 - 0.012 14.3 0.0 0.021 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) P12 PF12669.2 KEG05734.1 - 0.026 14.7 0.4 0.11 12.6 0.0 2.0 2 0 0 2 2 2 0 Virus attachment protein p12 family S1FA PF04689.8 KEG05734.1 - 0.033 14.0 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 DNA binding protein S1FA TrbL PF04610.9 KEG05734.1 - 0.033 13.8 0.0 0.051 13.2 0.0 1.2 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein Rifin_STEVOR PF02009.11 KEG05734.1 - 0.038 13.6 0.0 0.098 12.2 0.0 1.6 2 0 0 2 2 2 0 Rifin/stevor family CD34_antigen PF06365.7 KEG05734.1 - 0.045 13.4 0.0 0.24 10.9 0.0 2.0 2 0 0 2 2 2 0 CD34/Podocalyxin family FAM163 PF15069.1 KEG05734.1 - 0.085 13.4 0.0 0.19 12.3 0.0 1.7 1 1 0 1 1 1 0 FAM163 family IncA PF04156.9 KEG05734.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 IncA protein HpaP PF09483.5 KEG05734.1 - 0.33 10.8 5.7 0.53 10.2 4.0 1.3 1 0 0 1 1 1 0 Type III secretion protein (HpaP) STOP PF05217.7 KEG05735.1 - 9.4e-12 45.1 19.5 0.00018 21.2 0.1 4.0 1 1 3 4 4 4 4 STOP protein SdiA-regulated PF06977.6 KEG05736.1 - 0.13 11.1 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 SdiA-regulated Mucin PF01456.12 KEG05737.1 - 0.0016 18.1 0.7 0.0029 17.3 0.0 1.8 2 0 0 2 2 2 1 Mucin-like glycoprotein Spc7 PF08317.6 KEG05737.1 - 0.061 11.9 3.4 0.11 11.1 2.4 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein COG2 PF06148.6 KEG05737.1 - 4.6 7.1 6.9 3.1 7.6 1.7 2.4 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 PKD_channel PF08016.7 KEG05739.1 - 3e-06 25.9 10.6 4.9e-06 25.2 7.4 1.3 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 KEG05739.1 - 0.0004 19.6 14.7 0.00092 18.5 10.2 1.5 1 0 0 1 1 1 1 Ion transport protein Citrate_synt PF00285.16 KEG05740.1 - 3.4e-96 322.0 0.0 4e-96 321.8 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase DUF793 PF05633.6 KEG05741.1 - 0.036 12.8 2.1 0.062 12.0 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF793) Macoilin PF09726.4 KEG05741.1 - 5.5 5.1 14.6 7.6 4.6 10.1 1.2 1 0 0 1 1 1 0 Transmembrane protein Fcf1 PF04900.7 KEG05742.1 - 2.2e-35 120.8 2.3 2.2e-35 120.8 1.6 1.5 2 0 0 2 2 2 1 Fcf1 Apc3 PF12895.2 KEG05743.1 - 0.0032 17.5 4.7 0.0055 16.8 2.3 2.1 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KEG05743.1 - 0.012 16.0 0.3 0.059 13.8 0.2 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 KEG05743.1 - 0.018 14.9 0.4 0.074 12.9 0.3 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Hydrolase_4 PF12146.3 KEG05743.1 - 0.038 13.8 0.1 3.2 7.6 0.1 2.5 2 0 0 2 2 2 0 Putative lysophospholipase TPR_11 PF13414.1 KEG05743.1 - 0.056 13.0 0.1 0.14 11.8 0.1 1.7 1 0 0 1 1 1 0 TPR repeat TPR_3 PF07720.7 KEG05743.1 - 0.056 13.2 0.5 0.11 12.3 0.4 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 KEG05743.1 - 0.058 13.0 0.3 0.17 11.5 0.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_4 PF07721.9 KEG05743.1 - 0.13 12.7 0.0 0.13 12.7 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF605 PF04652.11 KEG05744.1 - 9.9e-38 130.5 11.6 2.2e-36 126.0 8.1 2.0 1 1 0 1 1 1 1 Vta1 like HrpB2 PF09487.5 KEG05745.1 - 0.16 12.1 2.0 0.22 11.7 0.2 2.2 1 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB2) Red1 PF07964.6 KEG05746.1 - 9.4 4.2 12.5 12 3.8 8.7 1.1 1 0 0 1 1 1 0 Rec10 / Red1 NPV_P10 PF05531.7 KEG05748.1 - 0.0018 18.5 8.5 0.64 10.2 0.4 3.3 1 1 3 4 4 4 2 Nucleopolyhedrovirus P10 protein UvrD_C PF13361.1 KEG05748.1 - 0.14 11.6 14.0 0.18 11.2 9.7 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Reo_sigmaC PF04582.7 KEG05748.1 - 0.23 10.6 7.7 0.27 10.3 5.3 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Spectrin PF00435.16 KEG05748.1 - 0.26 11.6 29.7 0.13 12.5 7.3 2.3 1 1 1 2 2 2 0 Spectrin repeat HTH_41 PF14502.1 KEG05748.1 - 0.39 10.3 6.2 22 4.7 0.0 4.2 4 0 0 4 4 4 0 Helix-turn-helix domain FTA4 PF13093.1 KEG05748.1 - 0.41 10.0 28.7 0.98 8.8 8.7 2.3 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Syntaxin-6_N PF09177.6 KEG05748.1 - 0.54 10.7 25.0 0.35 11.3 7.7 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal ATP_Ca_trans_C PF12424.3 KEG05748.1 - 0.58 10.5 8.6 2.4 8.5 1.0 3.1 1 1 4 5 5 5 0 Plasma membrane calcium transporter ATPase C terminal Drf_FH3 PF06367.11 KEG05748.1 - 0.61 9.4 15.8 0.91 8.8 10.1 1.8 1 1 1 2 2 2 0 Diaphanous FH3 Domain Imm18 PF15566.1 KEG05748.1 - 0.67 9.3 8.5 20 4.6 0.2 3.6 1 1 2 3 3 3 0 Immunity protein 18 DUF4615 PF15393.1 KEG05748.1 - 0.9 9.7 19.7 0.79 9.9 2.2 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4615) DUF1843 PF08898.5 KEG05748.1 - 0.93 9.5 26.4 7.6 6.6 0.6 5.3 1 1 4 5 5 5 0 Domain of unknown function (DUF1843) FUSC PF04632.7 KEG05748.1 - 1 7.7 13.4 1.1 7.5 9.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3584 PF12128.3 KEG05748.1 - 1.3 6.2 30.1 2 5.6 20.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Uds1 PF15456.1 KEG05748.1 - 1.4 8.8 33.5 4.6 7.2 6.1 3.9 1 1 4 5 5 5 0 Up-regulated During Septation BLOC1_2 PF10046.4 KEG05748.1 - 1.4 9.0 18.1 4.4 7.4 3.3 2.8 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Rab5-bind PF09311.6 KEG05748.1 - 1.5 8.6 41.2 1.8 8.4 27.5 1.9 1 1 0 1 1 1 0 Rabaptin-like protein Vps53_N PF04100.7 KEG05748.1 - 1.6 7.4 18.7 0.17 10.6 4.6 2.2 1 1 1 2 2 2 0 Vps53-like, N-terminal FliD_N PF02465.13 KEG05748.1 - 2.5 8.5 13.7 47 4.4 1.1 3.2 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF3373 PF11853.3 KEG05748.1 - 3.4 6.0 17.3 1.4 7.3 3.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3373) GAS PF13851.1 KEG05748.1 - 4 6.5 32.9 0.66 9.1 19.4 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.5 KEG05748.1 - 4 7.5 17.7 3.1 7.9 7.9 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ETF_alpha PF00766.14 KEG05748.1 - 5.6 6.6 5.3 39 3.9 0.1 3.7 1 1 3 4 4 4 0 Electron transfer flavoprotein FAD-binding domain Phycobilisome PF00502.14 KEG05748.1 - 5.6 6.6 7.5 20 4.8 0.3 3.0 1 1 4 5 5 5 0 Phycobilisome protein Filament PF00038.16 KEG05748.1 - 7.3 5.9 36.3 5.8 6.2 6.8 2.2 1 1 1 2 2 2 0 Intermediate filament protein Laminin_I PF06008.9 KEG05748.1 - 7.5 5.7 30.7 0.089 12.0 6.7 2.2 1 1 1 2 2 2 0 Laminin Domain I NPV_P10 PF05531.7 KEG05749.1 - 0.00012 22.1 16.5 1.9 8.7 1.4 6.2 3 2 4 7 7 7 3 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 KEG05749.1 - 0.0035 16.5 10.4 0.56 9.3 0.4 3.3 1 1 2 3 3 3 2 Reovirus sigma C capsid protein Occludin_ELL PF07303.8 KEG05749.1 - 0.028 15.1 59.7 0.093 13.4 6.8 5.5 1 1 4 5 5 5 0 Occludin homology domain FliD_N PF02465.13 KEG05749.1 - 0.29 11.5 26.9 5 7.5 0.5 6.3 2 2 2 6 6 6 0 Flagellar hook-associated protein 2 N-terminus BLOC1_2 PF10046.4 KEG05749.1 - 0.45 10.6 46.7 1.2 9.3 1.8 6.5 1 1 5 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Seryl_tRNA_N PF02403.17 KEG05749.1 - 1 9.4 54.2 0.19 11.7 4.0 4.8 1 1 4 5 5 5 0 Seryl-tRNA synthetase N-terminal domain Mucin PF01456.12 KEG05753.1 - 8.5e-05 22.3 10.7 8.5e-05 22.3 7.4 2.1 1 1 1 2 2 2 1 Mucin-like glycoprotein DUF3584 PF12128.3 KEG05753.1 - 0.045 11.0 3.3 0.054 10.8 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_13 PF13166.1 KEG05753.1 - 0.087 11.2 2.5 0.092 11.1 1.7 1.3 1 0 0 1 1 1 0 AAA domain DUF4140 PF13600.1 KEG05753.1 - 0.1 13.0 4.5 0.29 11.6 3.1 1.8 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF3080 PF11279.3 KEG05753.1 - 0.16 11.0 1.6 0.23 10.5 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) DUF605 PF04652.11 KEG05753.1 - 0.35 10.2 25.4 0.45 9.8 17.6 1.1 1 0 0 1 1 1 0 Vta1 like Syntaxin-6_N PF09177.6 KEG05753.1 - 0.55 10.6 4.2 2.4 8.6 2.5 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF2562 PF10814.3 KEG05753.1 - 1.6 8.6 7.7 3.1 7.7 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2562) XhlA PF10779.4 KEG05753.1 - 3.3 7.6 4.9 7.8 6.4 2.7 2.2 1 1 0 1 1 1 0 Haemolysin XhlA DUF883 PF05957.8 KEG05753.1 - 4.7 7.6 8.7 2 8.8 3.3 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Fmp27_WPPW PF10359.4 KEG05753.1 - 5.7 5.2 8.5 1.9 6.7 3.9 1.5 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF4551 PF15087.1 KEG05753.1 - 7 4.8 14.0 9.5 4.4 9.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) WEMBL PF05701.6 KEG05754.1 - 0.0047 15.4 5.9 0.005 15.3 4.1 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light TarH PF02203.10 KEG05754.1 - 0.088 12.6 4.1 0.12 12.1 2.8 1.3 1 0 0 1 1 1 0 Tar ligand binding domain homologue Mucin PF01456.12 KEG05754.1 - 0.56 9.9 10.4 1.2 8.8 7.2 1.6 1 1 0 1 1 1 0 Mucin-like glycoprotein CAP160 PF07918.6 KEG05754.1 - 9.5 5.9 8.8 0.25 10.9 0.8 2.4 3 0 0 3 3 3 0 CAP160 repeat Cytochrom_C PF00034.16 KEG05755.1 - 9.2e-09 36.0 0.0 1.3e-08 35.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 KEG05755.1 - 3.8e-05 23.7 1.2 0.00036 20.6 0.8 2.1 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III DUF3882 PF07066.6 KEG05756.1 - 0.073 12.9 1.0 32 4.3 0.0 3.4 3 1 0 3 3 3 0 Lactococcus phage M3 protein Peripla_BP_6 PF13458.1 KEG05757.1 - 0.0097 15.2 0.1 0.017 14.4 0.0 1.4 1 1 0 1 1 1 1 Periplasmic binding protein Guanylate_cyc PF00211.15 KEG05758.1 - 0.00033 20.0 0.0 0.00044 19.6 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Orthoreo_P10 PF07204.6 KEG05758.1 - 0.014 15.1 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Tweety PF04906.8 KEG05758.1 - 0.086 11.2 0.0 0.094 11.1 0.0 1.0 1 0 0 1 1 1 0 Tweety EphA2_TM PF14575.1 KEG05758.1 - 0.095 13.1 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SUI1 PF01253.17 KEG05759.1 - 1.7e-22 79.0 0.1 2.3e-22 78.5 0.1 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 RIP PF00161.14 KEG05759.1 - 0.0072 15.5 0.0 0.0088 15.2 0.0 1.1 1 0 0 1 1 1 1 Ribosome inactivating protein Methyltransf_26 PF13659.1 KEG05760.1 - 0.028 14.4 1.1 0.38 10.8 0.2 2.5 1 1 1 2 2 2 0 Methyltransferase domain MTS PF05175.9 KEG05760.1 - 0.063 12.6 0.0 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Ribosomal_S8 PF00410.14 KEG05761.1 - 4.5e-24 84.7 0.0 6.2e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 DUF1995 PF09353.5 KEG05761.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1995) Mucin PF01456.12 KEG05764.1 - 1.3e-07 31.5 9.4 1.3e-07 31.5 6.5 4.2 3 1 0 3 3 3 1 Mucin-like glycoprotein DUF1241 PF06840.6 KEG05764.1 - 0.0086 15.3 0.3 0.039 13.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1241) DUF2277 PF10041.4 KEG05764.1 - 0.066 13.1 0.1 0.066 13.1 0.1 3.8 3 2 1 4 4 4 0 Uncharacterized conserved protein (DUF2277) DUF3584 PF12128.3 KEG05764.1 - 0.45 7.7 15.0 0.61 7.3 2.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) BAR PF03114.13 KEG05764.1 - 3.6 7.0 8.2 0.33 10.4 0.1 2.6 3 0 0 3 3 3 0 BAR domain ChaC PF04752.7 KEG05765.1 - 5e-13 49.4 0.1 5.3e-13 49.3 0.1 1.0 1 0 0 1 1 1 1 ChaC-like protein DUF2317 PF10079.4 KEG05767.1 - 0.012 14.3 0.4 1.5 7.2 0.1 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2317) DUF4653 PF15546.1 KEG05767.1 - 0.034 13.4 0.7 0.39 9.9 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4653) TPPII_N PF12583.3 KEG05771.1 - 0.14 12.3 0.9 0.21 11.6 0.7 1.3 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal DUF1469 PF07332.6 KEG05772.1 - 1 9.0 5.2 1.4 8.6 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) TOH_N PF12549.3 KEG05773.1 - 0.15 11.7 0.0 0.63 9.6 0.0 1.9 2 0 0 2 2 2 0 Tyrosine hydroxylase N terminal Neogenin_C PF06583.7 KEG05775.1 - 0.7 9.4 7.2 1 8.8 5.0 1.2 1 0 0 1 1 1 0 Neogenin C-terminus WD40 PF00400.27 KEG05777.1 - 0.073 12.9 0.0 0.82 9.6 0.0 2.5 2 0 0 2 2 2 0 WD domain, G-beta repeat Peripla_BP_6 PF13458.1 KEG05778.1 - 7.2e-13 48.5 0.2 7.8e-12 45.1 0.0 2.6 3 0 0 3 3 3 1 Periplasmic binding protein DUF3460 PF11943.3 KEG05778.1 - 0.11 12.5 0.7 4.9 7.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3460) MFS_1 PF07690.11 KEG05780.1 - 4e-33 114.5 34.0 5.5e-24 84.5 4.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ins145_P3_rec PF08709.6 KEG05780.1 - 0.14 11.1 1.3 0.22 10.5 0.9 1.2 1 0 0 1 1 1 0 Inositol 1,4,5-trisphosphate/ryanodine receptor Androgen_recep PF02166.11 KEG05780.1 - 0.68 8.7 7.6 0.089 11.6 1.5 1.9 2 0 0 2 2 2 0 Androgen receptor PUF PF00806.14 KEG05781.1 - 7e-18 63.0 0.3 0.0032 16.8 0.0 5.2 5 0 0 5 5 5 4 Pumilio-family RNA binding repeat Peptidase_C58 PF03543.9 KEG05781.1 - 0.065 12.7 0.1 0.29 10.6 0.0 2.0 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen AAA PF00004.24 KEG05782.1 - 2.1e-45 154.1 0.0 5.2e-45 152.8 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KEG05782.1 - 6.9e-10 38.7 0.0 2.1e-09 37.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KEG05782.1 - 5e-07 29.8 0.1 6.2e-06 26.3 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KEG05782.1 - 2.4e-06 27.7 0.6 0.00043 20.4 0.3 3.0 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.9 KEG05782.1 - 6.9e-06 26.0 0.4 1.6e-05 24.9 0.0 1.8 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 KEG05782.1 - 0.00016 21.3 0.1 0.00044 19.9 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain DUF815 PF05673.8 KEG05782.1 - 0.00017 20.5 0.0 0.00028 19.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 KEG05782.1 - 0.00021 21.2 0.0 0.00039 20.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KEG05782.1 - 0.00024 20.9 0.0 0.0018 18.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KEG05782.1 - 0.00038 21.2 0.0 0.00071 20.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KEG05782.1 - 0.00046 19.2 0.0 0.0013 17.7 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 KEG05782.1 - 0.00081 18.8 0.9 0.029 13.7 0.0 2.3 1 1 1 2 2 2 1 AAA domain NACHT PF05729.7 KEG05782.1 - 0.0013 18.4 0.4 0.05 13.2 0.0 3.1 3 1 0 3 3 3 1 NACHT domain NTPase_1 PF03266.10 KEG05782.1 - 0.0025 17.5 0.2 0.035 13.8 0.0 2.7 3 0 0 3 3 3 1 NTPase AAA_30 PF13604.1 KEG05782.1 - 0.004 16.7 0.0 0.032 13.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KEG05782.1 - 0.0058 15.8 0.0 0.015 14.5 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF465 PF04325.8 KEG05782.1 - 0.0062 16.2 3.9 0.013 15.1 2.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF465) IstB_IS21 PF01695.12 KEG05782.1 - 0.0065 15.9 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 KEG05782.1 - 0.011 14.4 0.1 0.029 13.1 0.0 1.5 1 1 0 1 1 1 0 TIP49 C-terminus AAA_24 PF13479.1 KEG05782.1 - 0.013 15.1 0.1 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KEG05782.1 - 0.013 15.6 0.0 0.028 14.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.1 KEG05782.1 - 0.016 15.0 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 KEG05782.1 - 0.018 14.5 0.0 0.86 9.0 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 KEG05782.1 - 0.018 14.7 0.1 0.26 10.9 0.0 2.1 1 1 1 2 2 2 0 Archaeal ATPase AAA_3 PF07726.6 KEG05782.1 - 0.021 14.4 0.0 0.071 12.7 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.13 KEG05782.1 - 0.027 14.1 0.0 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_18 PF13238.1 KEG05782.1 - 0.028 14.7 0.0 0.056 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 KEG05782.1 - 0.033 13.7 0.0 0.098 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KEG05782.1 - 0.033 13.2 0.0 0.063 12.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin UPF0079 PF02367.12 KEG05782.1 - 0.043 13.4 0.0 0.087 12.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 cobW PF02492.14 KEG05782.1 - 0.054 12.9 0.0 0.18 11.2 0.0 1.8 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain KaiC PF06745.8 KEG05782.1 - 0.065 12.3 0.4 0.72 8.9 0.0 2.6 3 0 0 3 3 3 0 KaiC ABC_tran PF00005.22 KEG05782.1 - 0.11 12.8 0.0 0.43 10.8 0.0 2.3 1 1 0 1 1 1 0 ABC transporter Parvo_NS1 PF01057.12 KEG05782.1 - 0.15 10.8 0.0 0.29 9.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Mucin PF01456.12 KEG05784.1 - 0.61 9.8 35.5 0.024 14.4 3.5 3.7 2 1 1 3 3 3 0 Mucin-like glycoprotein Kinesin PF00225.18 KEG05785.1 - 3.5e-21 75.2 0.0 3.9e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain ResIII PF04851.10 KEG05785.1 - 0.016 15.0 0.1 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_24 PF13479.1 KEG05785.1 - 0.041 13.4 0.4 0.058 12.9 0.2 1.1 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KEG05785.1 - 0.056 12.6 0.1 0.088 12.0 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein T2SE PF00437.15 KEG05785.1 - 0.076 11.9 0.0 0.081 11.8 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.1 KEG05785.1 - 0.086 12.4 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KEG05785.1 - 0.094 12.9 0.1 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) G-patch PF01585.18 KEG05786.1 - 2e-11 43.4 2.3 3.6e-11 42.6 1.6 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KEG05786.1 - 0.00054 19.7 1.0 0.00054 19.7 0.7 2.3 2 1 0 2 2 2 1 DExH-box splicing factor binding site API5 PF05918.6 KEG05786.1 - 2.3 6.5 5.4 3.2 6.1 3.8 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Galactosyl_T PF01762.16 KEG05788.1 - 1.5e-07 31.2 0.1 0.00025 20.6 0.0 3.0 2 1 1 3 3 3 3 Galactosyltransferase Peripla_BP_6 PF13458.1 KEG05789.1 - 3.1e-09 36.6 0.1 7.1e-09 35.4 0.0 1.6 2 0 0 2 2 2 1 Periplasmic binding protein VID27 PF08553.5 KEG05790.1 - 3.1e-17 62.1 0.0 8e-17 60.7 0.0 1.6 1 1 1 2 2 2 1 VID27 cytoplasmic protein DUF2946 PF11162.3 KEG05791.1 - 0.012 15.7 0.2 0.015 15.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) Shisa PF13908.1 KEG05792.1 - 4e-06 27.1 6.9 0.0069 16.5 0.2 2.1 1 1 1 2 2 2 2 Wnt and FGF inhibitory regulator Herpes_gE PF02480.11 KEG05792.1 - 0.00032 19.0 0.4 0.056 11.6 0.0 2.0 1 1 1 2 2 2 2 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 KEG05792.1 - 0.00046 20.5 0.0 0.41 11.0 0.0 2.2 2 0 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain WBP-1 PF11669.3 KEG05792.1 - 0.00098 19.1 1.4 1.1 9.3 0.1 2.3 2 0 0 2 2 2 2 WW domain-binding protein 1 IncA PF04156.9 KEG05792.1 - 0.0016 18.0 1.0 0.28 10.7 0.1 2.1 1 1 1 2 2 2 2 IncA protein DUF4448 PF14610.1 KEG05792.1 - 0.0033 16.9 0.2 0.73 9.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) Frag1 PF10277.4 KEG05792.1 - 0.014 14.8 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family DUF4131 PF13567.1 KEG05792.1 - 0.019 14.3 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) YajC PF02699.10 KEG05792.1 - 0.02 14.5 0.0 7.8 6.2 0.0 2.2 2 0 0 2 2 2 0 Preprotein translocase subunit DUF2668 PF10873.3 KEG05792.1 - 0.04 14.0 11.3 0.8 9.8 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2668) DUF1191 PF06697.7 KEG05792.1 - 0.043 12.6 0.0 0.44 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1191) Rhabdo_glycop PF00974.13 KEG05792.1 - 0.056 11.6 8.0 0.22 9.7 1.0 2.1 1 1 1 2 2 2 0 Rhabdovirus spike glycoprotein Orthoreo_P10 PF07204.6 KEG05792.1 - 0.15 11.8 3.6 1.9 8.2 0.1 2.2 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 TMEM51 PF15345.1 KEG05792.1 - 0.22 11.1 0.8 11 5.6 0.1 2.1 1 1 1 2 2 2 0 Transmembrane protein 51 LST1 PF05083.8 KEG05792.1 - 0.51 10.3 7.1 4.4 7.3 0.5 2.2 2 0 0 2 2 2 0 LST-1 protein Mucin PF01456.12 KEG05792.1 - 0.59 9.9 8.2 3.1 7.5 0.4 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Corona_S2 PF01601.11 KEG05792.1 - 0.94 7.4 8.2 0.037 12.1 0.7 1.8 2 0 0 2 2 2 0 Coronavirus S2 glycoprotein MDFI PF15316.1 KEG05792.1 - 1.1 9.2 17.7 0.28 11.1 1.7 2.4 2 1 0 2 2 2 0 MyoD family inhibitor Pdase_C33_assoc PF14756.1 KEG05792.1 - 2 8.0 10.3 5.2 6.7 1.1 2.2 2 0 0 2 2 2 0 Peptidase_C33-associated domain Spatacsin_C PF14649.1 KEG05794.1 - 0.04 12.7 0.1 0.075 11.8 0.1 1.4 1 0 0 1 1 1 0 Spatacsin C-terminus Mucin PF01456.12 KEG05795.1 - 4.6e-05 23.2 10.4 4.6e-05 23.2 7.2 2.8 2 1 0 2 2 2 1 Mucin-like glycoprotein Reo_sigmaC PF04582.7 KEG05795.1 - 1 8.4 6.1 0.21 10.7 1.9 1.6 2 0 0 2 2 2 0 Reovirus sigma C capsid protein MGC-24 PF05283.6 KEG05795.1 - 4.4 7.0 16.4 1.8 8.2 8.4 2.4 1 1 1 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) GTP_CH_N PF12471.3 KEG05796.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 GTP cyclohydrolase N terminal CHB_HEX_C PF03174.8 KEG05797.1 - 0.00012 21.8 1.3 0.00033 20.4 0.9 1.8 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.1 KEG05797.1 - 0.0027 17.7 0.6 0.0092 16.0 0.4 2.0 1 0 0 1 1 1 1 Fn3 associated CHB_HEX_C_1 PF13290.1 KEG05797.1 - 0.0076 16.0 1.7 0.028 14.2 1.2 2.0 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain K_channel_TID PF07941.6 KEG05799.1 - 0.0092 16.1 2.6 0.0092 16.1 1.8 2.4 2 1 0 2 2 2 1 Potassium channel Kv1.4 tandem inactivation domain Sigma70_r3 PF04539.11 KEG05799.1 - 0.023 14.5 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-70 region 3 Sporozoite_P67 PF05642.6 KEG05799.1 - 0.079 10.8 2.6 0.062 11.1 1.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF1869 PF08956.5 KEG05799.1 - 0.1 12.2 0.2 0.7 9.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1869) Band_7 PF01145.20 KEG05800.1 - 3.2e-29 102.0 0.1 3.2e-29 102.0 0.1 1.8 1 1 1 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 KEG05800.1 - 0.0046 16.4 0.3 0.0076 15.7 0.0 1.5 2 0 0 2 2 2 1 SPFH domain-Band 7 family AAA_14 PF13173.1 KEG05801.1 - 7.7e-05 22.6 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEG05801.1 - 0.00012 22.9 0.1 0.00045 21.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KEG05801.1 - 0.011 16.0 0.1 0.046 14.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KEG05801.1 - 0.015 15.0 0.2 0.066 12.9 0.1 1.8 1 1 0 1 1 1 0 Archaeal ATPase AAA_16 PF13191.1 KEG05801.1 - 0.14 12.1 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DUF4201 PF13870.1 KEG05802.1 - 0.021 14.2 2.0 0.052 12.9 1.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF972 PF06156.8 KEG05802.1 - 5.4 7.4 7.0 1.2 9.4 0.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF972) HSP70 PF00012.15 KEG05803.1 - 3.1e-45 154.1 0.1 3.4e-45 154.0 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein Asp_decarbox PF02261.11 KEG05803.1 - 0.0041 16.7 0.0 0.0052 16.3 0.0 1.3 1 0 0 1 1 1 1 Aspartate decarboxylase EphA2_TM PF14575.1 KEG05805.1 - 0.011 16.0 0.1 0.032 14.5 0.1 1.9 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.10 KEG05805.1 - 0.091 12.3 1.5 0.18 11.3 1.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Herpes_capsid PF06112.6 KEG05808.1 - 0.27 11.2 3.4 0.64 10.0 2.4 1.6 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein IQ PF00612.22 KEG05810.1 - 0.033 13.8 1.0 0.033 13.8 0.7 2.1 2 0 0 2 2 2 0 IQ calmodulin-binding motif Homeobox_KN PF05920.6 KEG05810.1 - 0.047 13.3 0.3 0.081 12.6 0.2 1.4 1 0 0 1 1 1 0 Homeobox KN domain RskA PF10099.4 KEG05810.1 - 0.05 13.3 3.2 0.053 13.2 2.2 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA BAF1_ABF1 PF04684.8 KEG05810.1 - 0.4 9.4 2.3 0.42 9.4 1.6 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor KH_1 PF00013.24 KEG05811.1 - 4.3e-18 64.7 0.2 2e-07 30.5 0.1 3.8 4 0 0 4 4 4 3 KH domain KH_3 PF13014.1 KEG05811.1 - 7.3e-09 35.0 0.4 0.0018 17.8 0.0 2.8 3 0 0 3 3 3 2 KH domain TPR_16 PF13432.1 KEG05811.1 - 0.059 14.0 0.7 0.059 14.0 0.5 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat SLS PF14611.1 KEG05811.1 - 0.099 12.0 0.0 24 4.2 0.0 3.0 2 1 1 3 3 3 0 Mitochondrial inner-membrane-bound regulator Trichoplein PF13868.1 KEG05812.1 - 8.3e-05 21.1 77.7 0.00011 20.7 53.9 1.1 1 0 0 1 1 1 1 Tumour suppressor, Mitostatin CoA_binding_3 PF13727.1 KEG05812.1 - 0.28 10.9 3.8 0.18 11.6 0.6 2.1 1 1 1 2 2 2 0 CoA-binding domain Cys_rich_FGFR PF00839.12 KEG05813.1 - 0.013 15.4 1.2 0.27 11.2 0.0 2.4 2 0 0 2 2 2 0 Cysteine rich repeat CHCH PF06747.8 KEG05813.1 - 0.053 13.4 0.3 0.54 10.2 0.0 2.5 2 0 0 2 2 2 0 CHCH domain TRAP_alpha PF03896.11 KEG05813.1 - 0.076 11.9 0.0 0.092 11.7 0.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Pet191_N PF10203.4 KEG05813.1 - 0.079 13.0 0.2 0.44 10.6 0.1 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Conotoxin PF02950.12 KEG05813.1 - 0.23 12.2 3.5 4.2 8.2 2.5 2.5 1 1 0 1 1 1 0 Conotoxin Zip PF02535.17 KEG05813.1 - 0.35 9.8 22.2 0.49 9.3 15.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Macoilin PF09726.4 KEG05813.1 - 1.1 7.3 5.8 1.2 7.3 4.0 1.1 1 0 0 1 1 1 0 Transmembrane protein LRR_1 PF00560.28 KEG05814.1 - 0.21 11.7 0.6 4.7 7.6 0.0 2.5 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_7 PF13504.1 KEG05814.1 - 0.31 11.3 1.5 11 6.7 0.1 2.9 3 0 0 3 3 3 0 Leucine rich repeat MarR_2 PF12802.2 KEG05815.1 - 0.1 12.3 0.3 0.14 11.8 0.2 1.2 1 0 0 1 1 1 0 MarR family MFS_1 PF07690.11 KEG05817.1 - 2.6e-06 26.4 13.4 0.00011 21.0 4.2 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily EBP PF05241.7 KEG05822.1 - 1.3e-43 148.2 1.8 1.9e-43 147.7 1.3 1.2 1 0 0 1 1 1 1 Emopamil binding protein Nitrate_red_gam PF02665.9 KEG05823.1 - 0.036 13.4 1.8 0.041 13.2 1.2 1.0 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Trm112p PF03966.11 KEG05824.1 - 2.7e-10 40.4 0.0 4e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Trm112p-like protein A2L_zn_ribbon PF08792.5 KEG05824.1 - 0.99 8.9 3.8 3.5 7.2 0.1 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain Guanylate_cyc PF00211.15 KEG05828.1 - 3.4e-20 72.1 0.1 4.1e-20 71.9 0.1 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF3824 PF12868.2 KEG05829.1 - 0.017 16.0 1.0 0.021 15.7 0.7 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) PIF1 PF05970.9 KEG05832.1 - 8.8e-21 74.2 1.0 5.2e-11 42.1 0.0 3.1 3 0 0 3 3 3 3 PIF1-like helicase Herpes_Helicase PF02689.9 KEG05832.1 - 0.00011 20.1 0.0 0.00017 19.5 0.0 1.1 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 KEG05832.1 - 0.00061 19.8 0.1 0.0019 18.2 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 KEG05832.1 - 0.017 14.6 0.1 0.042 13.3 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase LRR_4 PF12799.2 KEG05834.1 - 1.9e-07 30.5 0.0 0.013 15.0 0.0 3.2 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG05834.1 - 3.2e-06 26.7 0.0 0.0011 18.7 0.0 2.6 1 1 2 3 3 3 2 Leucine rich repeat LRR_6 PF13516.1 KEG05834.1 - 0.00012 21.7 0.1 0.2 11.8 0.0 3.4 3 1 0 3 3 3 1 Leucine Rich repeat LRR_1 PF00560.28 KEG05834.1 - 0.023 14.6 0.1 31 5.1 0.0 3.7 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.2 KEG05835.1 - 4e-13 48.6 0.0 0.00066 19.2 0.0 2.8 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG05835.1 - 4.8e-08 32.6 0.0 0.0099 15.6 0.0 2.9 1 1 2 3 3 3 3 Leucine rich repeat LRR_6 PF13516.1 KEG05835.1 - 1.4e-05 24.6 0.1 0.38 10.9 0.0 4.0 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.28 KEG05835.1 - 2e-05 23.9 1.1 18 5.8 0.1 4.5 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 KEG05835.1 - 0.0022 17.8 2.5 7.6 7.2 0.0 4.4 4 1 0 4 4 4 1 Leucine rich repeat Semialdhyde_dhC PF02774.13 KEG05837.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, dimerisation domain DUF2314 PF10077.4 KEG05838.1 - 0.052 13.6 0.1 0.063 13.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2314) DUF2704 PF10866.3 KEG05838.1 - 0.075 12.4 0.1 0.099 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2704) PNRC PF15365.1 KEG05839.1 - 0.088 12.8 1.9 0.31 11.0 1.4 2.0 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator Nbl1_Borealin_N PF10444.4 KEG05840.1 - 7.7 5.9 7.0 1.1 8.7 1.3 2.2 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal Complex1_51K PF01512.12 KEG05842.1 - 1.1e-44 151.7 0.0 1.9e-44 151.0 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 KEG05842.1 - 1.3e-19 69.0 0.1 2.5e-19 68.1 0.1 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 KEG05842.1 - 2.3e-08 33.7 0.0 5.2e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 SLBB domain DUF780 PF05611.6 KEG05842.1 - 0.18 12.5 2.2 0.41 11.3 1.5 1.5 1 0 0 1 1 1 0 Caenorhabditis elegans protein of unknown function (DUF780) HALZ PF02183.13 KEG05843.1 - 0.033 13.8 3.3 1.2 8.9 0.1 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper Pkinase PF00069.20 KEG05844.1 - 1.2e-29 103.3 0.0 1.5e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG05844.1 - 2.2e-13 49.8 0.0 3.1e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEG05844.1 - 6.6e-06 26.0 0.0 0.0021 17.8 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KEG05844.1 - 0.0025 16.9 0.0 0.0061 15.6 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KEG05844.1 - 0.013 14.4 0.0 0.027 13.4 0.0 1.5 2 0 0 2 2 2 0 Kinase-like RHSP PF07999.6 KEG05847.1 - 8.4e-96 321.2 1.5 2.2e-76 257.2 0.0 3.3 1 1 1 2 2 2 2 Retrotransposon hot spot protein Macro_2 PF14519.1 KEG05847.1 - 0.0033 16.5 0.0 0.04 13.0 0.0 2.1 2 0 0 2 2 2 1 Macro-like domain AAA_10 PF12846.2 KEG05847.1 - 0.0035 16.8 0.2 0.051 13.0 0.0 2.1 2 0 0 2 2 2 1 AAA-like domain HTH_17 PF12728.2 KEG05847.1 - 1.2 9.4 7.0 10 6.4 0.6 2.6 1 1 1 2 2 2 0 Helix-turn-helix domain Fructosamin_kin PF03881.9 KEG05848.1 - 4e-27 94.9 0.2 4.1e-27 94.9 0.1 1.0 1 0 0 1 1 1 1 Fructosamine kinase Peptidase_M8 PF01457.11 KEG05849.1 - 5.3e-15 54.7 0.0 5.7e-13 48.0 0.0 2.1 1 1 0 1 1 1 1 Leishmanolysin Mucin PF01456.12 KEG05849.1 - 0.0023 17.7 0.1 0.0035 17.1 0.1 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein Peptidase_M8 PF01457.11 KEG05850.1 - 8.4e-20 70.5 0.1 1e-19 70.3 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin MtmB PF05369.7 KEG05850.1 - 0.0037 15.4 0.0 0.0044 15.2 0.0 1.1 1 0 0 1 1 1 1 Monomethylamine methyltransferase MtmB PT-VENN PF04829.8 KEG05852.1 - 0.011 15.2 0.1 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif DUF2586 PF10758.4 KEG05853.1 - 0.038 13.0 0.0 2.7 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2586) Erp_C PF06780.6 KEG05853.1 - 0.56 10.0 6.2 0.56 10.0 2.8 2.1 1 1 0 1 1 1 0 Erp protein C-terminus PPR_2 PF13041.1 KEG05854.1 - 5.2e-05 23.1 0.0 0.0056 16.6 0.0 2.4 2 0 0 2 2 2 2 PPR repeat family PPR_3 PF13812.1 KEG05854.1 - 0.0071 16.5 2.1 1.5 9.2 0.0 3.5 2 2 0 3 3 3 2 Pentatricopeptide repeat domain WD40 PF00400.27 KEG05855.1 - 0.11 12.3 0.1 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 WD domain, G-beta repeat Galactosyl_T PF01762.16 KEG05856.1 - 4.3e-05 23.1 0.0 0.00083 19.0 0.0 2.3 2 0 0 2 2 2 1 Galactosyltransferase Mucin PF01456.12 KEG05860.1 - 0.0019 18.0 20.9 0.43 10.3 0.2 3.2 2 2 0 2 2 2 2 Mucin-like glycoprotein Mnd1 PF03962.10 KEG05860.1 - 2.9 7.5 15.6 0.15 11.7 1.3 2.9 2 1 1 3 3 3 0 Mnd1 family MGC-24 PF05283.6 KEG05860.1 - 5 6.8 15.0 0.89 9.3 0.3 2.7 2 1 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) IMS_C PF11799.3 KEG05863.1 - 1.6e-07 31.3 0.0 2.4e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain Cwf_Cwc_15 PF04889.7 KEG05863.1 - 0.0072 16.0 2.6 0.012 15.3 1.8 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.7 KEG05863.1 - 9.3 4.0 8.3 11 3.7 5.8 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2959 PF11172.3 KEG05864.1 - 0.043 13.5 3.6 0.061 13.0 1.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2959) Fib_alpha PF08702.5 KEG05864.1 - 0.22 11.6 0.1 0.22 11.6 0.1 3.1 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family CD99L2 PF12301.3 KEG05868.1 - 0.019 14.6 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 CD99 antigen like protein 2 Shisa PF13908.1 KEG05869.1 - 5.1e-05 23.5 0.1 0.00011 22.4 0.1 1.5 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Extensin_2 PF04554.8 KEG05869.1 - 2 8.3 6.7 0.24 11.2 1.6 1.7 2 0 0 2 2 2 0 Extensin-like region Neogenin_C PF06583.7 KEG05870.1 - 0.027 14.0 0.3 0.05 13.1 0.2 1.4 1 0 0 1 1 1 0 Neogenin C-terminus RCR PF12273.3 KEG05870.1 - 0.031 14.8 0.0 0.058 13.9 0.0 1.4 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red EphA2_TM PF14575.1 KEG05870.1 - 0.088 13.2 0.1 0.23 11.8 0.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain IncA PF04156.9 KEG05870.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 IncA protein Pex14_N PF04695.8 KEG05871.1 - 0.22 11.5 4.2 2.9 7.9 2.9 2.2 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RR_TM4-6 PF06459.7 KEG05871.1 - 0.31 10.9 12.0 0.39 10.5 8.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CENP-T PF15511.1 KEG05871.1 - 0.99 8.5 12.8 1.3 8.2 8.9 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Metallophos PF00149.23 KEG05872.1 - 1.2e-41 142.2 0.5 1.5e-41 142.0 0.4 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase VitD-bind_III PF09164.5 KEG05872.1 - 0.042 13.4 0.7 0.11 12.1 0.5 1.6 1 0 0 1 1 1 0 Vitamin D binding protein, domain III SelR PF01641.13 KEG05873.1 - 2.8e-23 81.9 0.4 3.1e-23 81.8 0.3 1.0 1 0 0 1 1 1 1 SelR domain GATA PF00320.22 KEG05873.1 - 0.086 12.1 0.9 0.23 10.8 0.1 2.0 2 0 0 2 2 2 0 GATA zinc finger Endonuclease_7 PF02945.10 KEG05873.1 - 0.097 12.4 0.3 0.092 12.4 0.2 1.2 1 0 0 1 1 1 0 Recombination endonuclease VII SelR PF01641.13 KEG05874.1 - 7.3e-12 45.0 0.0 1.1e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 SelR domain TF_Zn_Ribbon PF08271.7 KEG05874.1 - 0.066 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding DXP_reductoisom PF02670.11 KEG05879.1 - 0.014 15.9 0.0 0.016 15.7 0.0 1.1 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase MMS22L_N PF14910.1 KEG05879.1 - 0.16 10.1 0.0 0.18 10.0 0.0 1.0 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, N-terminal zf-B_box PF00643.19 KEG05881.1 - 2.1e-15 56.2 24.3 2.4e-08 33.7 4.8 2.8 3 0 0 3 3 3 2 B-box zinc finger Eapp_C PF10238.4 KEG05881.1 - 0.01 15.7 0.9 0.01 15.7 0.6 3.1 3 0 0 3 3 3 0 E2F-associated phosphoprotein Prominin PF05478.6 KEG05881.1 - 1.2 6.5 6.6 23 2.3 4.6 2.0 1 1 0 1 1 1 0 Prominin Thioredoxin PF00085.15 KEG05882.1 - 5e-07 29.3 0.0 1.1e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.1 KEG05882.1 - 9.4e-05 21.9 0.0 0.00019 21.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 KEG05882.1 - 0.00041 20.3 0.0 0.0009 19.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.1 KEG05882.1 - 0.0045 17.0 0.1 0.059 13.5 0.0 2.3 1 1 1 2 2 2 1 Thioredoxin-like DUF953 PF06110.6 KEG05882.1 - 0.035 13.5 0.2 0.11 11.9 0.1 1.8 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Metallophos PF00149.23 KEG05883.1 - 0.0023 17.3 0.1 0.0055 16.1 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase UCR_hinge PF02320.11 KEG05887.1 - 2e-20 72.4 5.0 2.3e-20 72.3 3.4 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein EF-hand_7 PF13499.1 KEG05889.1 - 1.6e-08 34.5 4.9 2e-05 24.6 0.2 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KEG05889.1 - 1.1e-05 24.8 0.7 0.00021 20.8 0.2 2.9 2 1 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 KEG05889.1 - 0.00036 19.6 0.2 0.00036 19.6 0.1 3.4 4 0 0 4 4 4 1 EF hand EF-hand_8 PF13833.1 KEG05889.1 - 0.0054 16.3 5.4 0.22 11.1 1.8 3.2 1 1 2 3 3 3 3 EF-hand domain pair DUF1456 PF07308.8 KEG05889.1 - 0.18 11.8 2.0 3.5 7.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) Peripla_BP_6 PF13458.1 KEG05894.1 - 3.5e-08 33.2 4.9 0.00036 20.0 0.1 2.7 2 1 0 2 2 2 2 Periplasmic binding protein Guanylate_cyc PF00211.15 KEG05894.1 - 0.0013 18.0 0.0 0.0026 17.1 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain NAD_binding_1 PF00175.16 KEG05895.1 - 6.4e-18 65.3 0.0 8.9e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KEG05895.1 - 2.5e-09 37.1 0.0 4e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KEG05895.1 - 2.7e-07 30.6 0.0 0.0019 18.1 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_2 PF00890.19 KEG05896.1 - 2.2e-07 30.1 4.6 2.9e-07 29.6 3.2 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KEG05896.1 - 1.5e-06 27.5 3.6 2e-06 27.1 2.5 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KEG05896.1 - 3.7e-06 26.0 2.6 4.7e-06 25.7 1.8 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 KEG05896.1 - 2e-05 24.5 1.0 2.6e-05 24.1 0.7 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEG05896.1 - 9.5e-05 21.4 1.8 0.00014 20.9 1.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KEG05896.1 - 0.00026 19.5 1.0 0.00032 19.2 0.7 1.1 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 KEG05896.1 - 0.0041 16.2 0.7 0.0054 15.8 0.5 1.1 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.16 KEG05896.1 - 0.0052 16.3 0.2 0.0063 16.0 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 KEG05896.1 - 0.012 16.0 1.8 0.019 15.3 1.3 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEG05896.1 - 0.015 15.2 0.9 0.026 14.5 0.6 1.4 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KEG05896.1 - 0.051 12.6 0.2 0.064 12.3 0.1 1.1 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.13 KEG05896.1 - 0.14 11.8 0.8 0.17 11.5 0.6 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 KEG05896.1 - 0.23 10.3 2.9 0.16 10.8 1.1 1.3 2 0 0 2 2 2 0 Lycopene cyclase protein Aldo_ket_red PF00248.16 KEG05898.1 - 2.9e-42 144.4 0.0 3.5e-42 144.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Sporozoite_P67 PF05642.6 KEG05900.1 - 0.065 11.0 4.1 0.069 11.0 2.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mucin PF01456.12 KEG05902.1 - 3.3e-05 23.6 2.4 4.7e-05 23.2 1.7 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF4033 PF13225.1 KEG05902.1 - 0.078 12.5 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4033) His_binding PF02098.11 KEG05903.1 - 0.3 10.9 3.3 0.36 10.6 0.7 2.2 1 1 1 2 2 2 0 Tick histamine binding protein Arch_ATPase PF01637.13 KEG05903.1 - 4.2 6.9 5.3 1.5 8.4 0.5 2.1 1 1 0 2 2 2 0 Archaeal ATPase RNase_H PF00075.19 KEG05904.1 - 5e-06 26.8 0.0 6.9e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 RNase H RVT_1 PF00078.22 KEG05906.1 - 7.4e-25 87.5 0.0 8.7e-25 87.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 KEG05907.1 - 0.1 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Cellulase PF00150.13 KEG05910.1 - 0.17 11.0 0.0 0.3 10.2 0.0 1.4 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Aa_trans PF01490.13 KEG05911.1 - 3.8e-48 163.9 21.9 4.4e-48 163.7 15.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RRM_6 PF14259.1 KEG05912.1 - 5e-08 32.8 0.0 9.5e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG05912.1 - 2.2e-05 24.2 0.0 3.7e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEG05912.1 - 7.2e-05 22.3 0.1 0.00014 21.4 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CAF1 PF04857.15 KEG05913.1 - 7.2e-50 169.7 0.0 1.8e-49 168.4 0.0 1.6 1 1 0 1 1 1 1 CAF1 family ribonuclease OmpH PF03938.9 KEG05913.1 - 0.025 14.5 2.8 0.042 13.7 2.0 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CSD PF00313.17 KEG05914.1 - 3.3e-13 49.1 0.0 3.4e-09 36.3 0.0 2.5 2 0 0 2 2 2 2 'Cold-shock' DNA-binding domain SAGA-Tad1 PF12767.2 KEG05914.1 - 0.44 10.1 4.4 1.1 8.8 0.3 2.3 2 1 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit POX PF07526.6 KEG05914.1 - 5.6 7.1 6.3 1.7 8.8 0.1 2.4 3 0 0 3 3 3 0 Associated with HOX IncA PF04156.9 KEG05916.1 - 0.0051 16.4 0.0 0.0069 15.9 0.0 1.1 1 0 0 1 1 1 1 IncA protein LAT PF15234.1 KEG05916.1 - 0.011 15.2 0.1 0.014 14.8 0.0 1.1 1 0 0 1 1 1 0 Linker for activation of T-cells VSP PF03302.8 KEG05916.1 - 0.023 13.3 0.2 0.029 13.0 0.1 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein EphA2_TM PF14575.1 KEG05916.1 - 0.033 14.5 0.0 0.065 13.6 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Neur_chan_memb PF02932.11 KEG05916.1 - 0.075 12.9 0.5 1.6 8.5 0.1 2.1 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF1191 PF06697.7 KEG05916.1 - 0.094 11.5 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Peripla_BP_6 PF13458.1 KEG05918.1 - 3.4e-06 26.6 2.9 0.073 12.4 0.0 3.0 2 1 0 2 2 2 2 Periplasmic binding protein DUF3481 PF11980.3 KEG05918.1 - 0.042 13.6 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) Mucin PF01456.12 KEG05919.1 - 0.025 14.3 15.1 0.085 12.6 10.4 1.8 1 1 0 1 1 1 0 Mucin-like glycoprotein DUF390 PF04094.9 KEG05920.1 - 1.8 6.5 12.5 2.2 6.2 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) SOG2 PF10428.4 KEG05920.1 - 3.8 6.0 7.2 4.1 5.9 5.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Cyclin PF08613.6 KEG05921.1 - 1.5e-15 57.8 0.1 2.2e-15 57.3 0.1 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KEG05921.1 - 0.0005 19.6 0.0 0.00086 18.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain APC_CDC26 PF10471.4 KEG05922.1 - 2 9.2 9.9 9.6 7.0 1.3 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 DUF3808 PF10300.4 KEG05929.1 - 1.7e-17 63.1 0.0 3.6e-17 62.0 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) HIM1 PF08732.5 KEG05929.1 - 0.11 10.9 0.0 0.14 10.5 0.0 1.1 1 0 0 1 1 1 0 HIM1 Carboxyl_trans PF01039.17 KEG05930.1 - 1.3e-123 412.9 0.0 1.6e-123 412.7 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain End_tail_spike PF12219.3 KEG05930.1 - 0.14 11.9 0.1 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Catalytic domain of bacteriophage endosialidase EF-hand_1 PF00036.27 KEG05931.1 - 2.2e-41 136.0 11.6 3.5e-10 38.4 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KEG05931.1 - 2.2e-37 126.9 3.7 2.5e-20 72.3 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KEG05931.1 - 2e-32 110.5 10.7 2.6e-15 55.7 0.4 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 KEG05931.1 - 4.8e-30 100.7 5.8 1.2e-09 37.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KEG05931.1 - 9.2e-27 91.1 7.1 1.7e-07 30.2 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 KEG05931.1 - 3e-15 55.8 0.1 7.5e-08 32.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KEG05931.1 - 6.6e-09 35.4 0.8 0.00028 20.5 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KEG05931.1 - 2.1e-07 30.9 0.0 0.0034 17.4 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 KEG05931.1 - 1.9e-06 27.3 1.8 0.18 11.4 0.0 3.9 4 1 1 5 5 5 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 KEG05931.1 - 3.4e-06 26.9 1.2 4.2e-05 23.4 0.2 2.3 2 0 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 KEG05931.1 - 0.00019 21.1 0.4 0.069 12.8 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 KEG05931.1 - 0.00026 20.6 0.1 0.013 15.0 0.1 2.5 1 1 0 1 1 1 1 Caleosin related protein EF-hand_like PF09279.6 KEG05931.1 - 0.00027 20.9 1.4 0.0022 17.9 0.1 2.4 2 1 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like RNA_pol_Rpb4 PF03874.11 KEG05931.1 - 0.0037 17.2 0.5 1.7 8.6 0.1 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb4 DUF1103 PF06513.6 KEG05931.1 - 0.0054 16.1 1.3 0.0062 15.9 0.9 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) SpoVIF PF14069.1 KEG05931.1 - 0.041 13.6 0.9 0.81 9.4 0.1 2.6 3 0 0 3 3 3 0 Stage VI sporulation protein F Toprim_2 PF13155.1 KEG05931.1 - 0.043 14.1 0.5 16 5.9 0.1 2.7 1 1 2 3 3 3 0 Toprim-like LNS2 PF08235.8 KEG05931.1 - 0.045 13.3 0.0 0.33 10.4 0.0 1.9 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) Tenui_NCP PF04876.7 KEG05931.1 - 0.055 13.0 0.1 0.95 8.9 0.0 2.1 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein MotA_activ PF09114.5 KEG05931.1 - 0.079 12.7 0.1 13 5.5 0.0 2.3 2 0 0 2 2 2 0 Transcription factor MotA, activation domain DUF1880 PF08976.6 KEG05931.1 - 0.11 12.6 0.0 0.72 9.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) Poly_export PF02563.11 KEG05931.1 - 0.12 12.1 0.1 11 5.8 0.0 3.0 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein PB1 PF00564.19 KEG05931.1 - 1.1 8.9 3.3 40 3.9 0.0 3.5 2 2 2 4 4 4 0 PB1 domain HSP70 PF00012.15 KEG05940.1 - 1.4e-13 49.6 5.6 1.6e-13 49.5 3.9 1.0 1 0 0 1 1 1 1 Hsp70 protein Toxin_52 PF15605.1 KEG05940.1 - 0.016 15.0 0.2 0.057 13.3 0.1 1.8 1 1 1 2 2 2 0 Putative toxin 52 Pex19 PF04614.7 KEG05940.1 - 0.054 13.1 2.3 0.087 12.4 1.6 1.4 1 1 0 1 1 1 0 Pex19 protein family HSP70 PF00012.15 KEG05941.1 - 2.1e-169 564.2 0.5 2.6e-169 563.9 0.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KEG05941.1 - 2.7e-12 45.9 0.0 6.2e-11 41.4 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 KEG05941.1 - 0.034 13.9 0.1 0.35 10.6 0.1 2.9 1 1 0 1 1 1 0 Cell division protein FtsA Asp_decarbox PF02261.11 KEG05941.1 - 0.042 13.4 0.1 0.079 12.5 0.0 1.4 1 0 0 1 1 1 0 Aspartate decarboxylase StbA PF06406.6 KEG05941.1 - 0.076 11.9 0.0 0.16 10.9 0.0 1.6 2 0 0 2 2 2 0 StbA protein Hydantoinase_A PF01968.13 KEG05941.1 - 0.088 11.8 0.3 1.6 7.7 0.1 2.4 1 1 1 2 2 2 0 Hydantoinase/oxoprolinase RRM_1 PF00076.17 KEG05944.1 - 2.6e-21 75.0 0.0 4.4e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG05944.1 - 2.3e-14 53.1 0.1 4.7e-14 52.1 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG05944.1 - 2e-11 43.5 0.0 3.5e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Y_phosphatase PF00102.22 KEG05945.1 - 2.7e-66 223.2 0.0 3.7e-66 222.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KEG05945.1 - 0.00083 19.6 0.2 0.0072 16.5 0.0 2.3 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 KEG05945.1 - 0.0027 17.2 0.0 0.0066 16.0 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 KEG05945.1 - 0.026 14.5 0.2 0.095 12.7 0.0 2.0 2 0 0 2 2 2 0 Inositol hexakisphosphate Aa_trans PF01490.13 KEG05946.1 - 5.7e-55 186.4 31.1 7e-55 186.1 21.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KEG05946.1 - 4.4e-06 25.7 11.9 4.4e-06 25.7 8.2 2.3 1 1 0 2 2 2 1 Tryptophan/tyrosine permease family AA_permease_2 PF13520.1 KEG05946.1 - 0.00071 18.2 18.8 0.00071 18.2 13.0 2.6 2 1 0 2 2 2 1 Amino acid permease zf-CCCH PF00642.19 KEG05947.1 - 0.0011 18.5 4.2 0.0011 18.5 2.9 2.3 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MGC-24 PF05283.6 KEG05947.1 - 0.24 11.1 5.1 0.072 12.8 1.0 1.9 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) YLP PF02757.12 KEG05948.1 - 0.091 12.4 0.3 0.32 10.8 0.2 2.0 1 0 0 1 1 1 0 YLP motif Peptidase_M8 PF01457.11 KEG05949.1 - 2.5e-52 177.9 12.8 7.5e-45 153.2 3.3 2.0 1 1 1 2 2 2 2 Leishmanolysin Peptidase_M8 PF01457.11 KEG05950.1 - 1.7e-41 142.1 0.0 2e-41 141.9 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M10 PF00413.19 KEG05950.1 - 0.17 11.5 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Matrixin YjgF_endoribonc PF14588.1 KEG05951.1 - 1.8e-34 118.8 0.6 2.1e-34 118.5 0.4 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.16 KEG05951.1 - 3.9e-23 81.4 0.2 5.7e-23 80.9 0.1 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP CDC45 PF02724.9 KEG05952.1 - 4.4 5.2 8.2 4.8 5.0 5.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1501 PF07394.7 KEG05953.1 - 0.059 12.2 0.1 0.062 12.1 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF2612 PF11041.3 KEG05955.1 - 0.089 12.3 0.0 0.097 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2612) MCC-bdg_PDZ PF10506.4 KEG05955.1 - 0.39 10.5 5.2 0.3 10.9 1.1 2.1 1 1 1 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF2312 PF10073.4 KEG05955.1 - 0.74 9.2 8.3 3.3 7.1 3.3 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) TMF_TATA_bd PF12325.3 KEG05955.1 - 1.6 8.4 7.7 1.1 8.9 3.4 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding CCDC-167 PF15188.1 KEG05955.1 - 4.7 7.2 6.4 10 6.1 1.5 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Arm PF00514.18 KEG05956.1 - 1.1e-39 132.9 20.4 1.8e-07 30.7 0.0 9.1 9 0 0 9 9 9 7 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KEG05956.1 - 8e-25 86.9 14.4 3.7e-07 30.3 0.0 5.0 2 1 3 5 5 5 5 HEAT repeats HEAT PF02985.17 KEG05956.1 - 2.3e-21 73.8 7.1 2.2e-05 24.1 0.0 7.6 7 0 0 7 7 7 6 HEAT repeat HEAT_EZ PF13513.1 KEG05956.1 - 1.1e-18 67.1 18.6 7.8e-05 23.0 0.2 6.5 4 1 3 7 7 6 6 HEAT-like repeat Adaptin_N PF01602.15 KEG05956.1 - 8.1e-13 47.5 2.8 2.4e-06 26.1 0.5 3.4 2 1 1 3 3 3 2 Adaptin N terminal region DNA_alkylation PF08713.6 KEG05956.1 - 2.6e-09 36.9 0.1 0.039 13.4 0.0 4.1 2 1 1 4 4 4 2 DNA alkylation repair enzyme Proteasom_PSMB PF10508.4 KEG05956.1 - 5.1e-09 34.9 0.3 3.5e-06 25.5 0.0 2.9 1 1 1 2 2 2 2 Proteasome non-ATPase 26S subunit Cnd1 PF12717.2 KEG05956.1 - 3.2e-07 30.3 0.2 0.0012 18.7 0.1 4.2 1 1 3 4 4 4 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 KEG05956.1 - 6.7e-06 25.6 0.5 0.062 12.6 0.1 2.9 1 1 1 2 2 2 2 CLASP N terminal V-ATPase_H_C PF11698.3 KEG05956.1 - 0.0023 17.8 0.9 0.15 11.9 0.1 3.4 4 0 0 4 4 4 1 V-ATPase subunit H DUF3730 PF12530.3 KEG05956.1 - 0.0029 17.5 5.1 0.03 14.2 0.7 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3730) Vac14_Fab1_bd PF12755.2 KEG05956.1 - 0.019 15.3 0.1 0.6 10.5 0.0 3.2 1 1 2 3 3 3 0 Vacuolar 14 Fab1-binding region OHCU_decarbox PF09349.5 KEG05956.1 - 0.022 15.0 2.0 1.2 9.3 0.0 3.3 2 1 1 3 3 3 0 OHCU decarboxylase Nipped-B_C PF12830.2 KEG05956.1 - 0.029 14.0 0.1 0.25 10.9 0.0 2.6 2 1 0 2 2 2 0 Sister chromatid cohesion C-terminus DUF3361 PF11841.3 KEG05956.1 - 0.038 13.7 1.3 9.7 5.8 0.0 3.6 2 1 2 4 4 4 0 Domain of unknown function (DUF3361) HEAT_PBS PF03130.11 KEG05956.1 - 0.05 14.0 14.9 2.2 8.9 0.2 6.1 7 0 0 7 7 5 0 PBS lyase HEAT-like repeat Ric8 PF10165.4 KEG05956.1 - 0.059 12.1 0.4 2.1 7.0 0.0 2.5 2 1 0 3 3 3 0 Guanine nucleotide exchange factor synembryn DUF3731 PF12531.3 KEG05956.1 - 0.1 12.1 1.7 6 6.3 0.4 3.5 2 1 1 3 3 3 0 DNA-K related protein Kinesin PF00225.18 KEG05958.1 - 1.2e-78 264.1 0.1 1.2e-78 264.1 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain DUF2229 PF09989.4 KEG05958.1 - 0.27 10.6 1.0 0.57 9.5 0.3 1.8 1 1 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) KaiC PF06745.8 KEG05958.1 - 0.77 8.8 8.7 0.27 10.3 0.6 2.8 3 0 0 3 3 3 0 KaiC AAA_25 PF13481.1 KEG05958.1 - 1.5 8.1 5.3 4 6.7 0.0 3.1 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KEG05958.1 - 1.5 8.9 5.0 1.7 8.8 0.0 3.4 2 1 0 2 2 2 0 AAA domain NDK PF00334.14 KEG05959.1 - 1.2e-13 51.0 0.1 1.4e-09 37.8 0.0 2.5 3 0 0 3 3 3 2 Nucleoside diphosphate kinase Mucin PF01456.12 KEG05960.1 - 0.0001 22.1 0.4 0.0001 22.1 0.3 2.7 2 1 0 2 2 2 1 Mucin-like glycoprotein IncA PF04156.9 KEG05960.1 - 0.12 11.9 9.6 0.46 10.0 6.6 2.0 1 1 0 1 1 1 0 IncA protein FliJ PF02050.11 KEG05960.1 - 7.4 6.6 16.2 4.6 7.3 3.1 2.3 1 1 1 2 2 2 0 Flagellar FliJ protein Spc7 PF08317.6 KEG05960.1 - 8.6 4.9 11.3 2 7.0 5.0 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein Mucin PF01456.12 KEG05961.1 - 0.0012 18.6 1.3 0.0012 18.6 0.9 2.5 2 2 1 3 3 3 1 Mucin-like glycoprotein DUF3391 PF11871.3 KEG05961.1 - 0.62 10.2 5.2 1.3 9.2 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) DUF3824 PF12868.2 KEG05962.1 - 0.021 15.7 2.3 9.3 7.1 0.5 2.7 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) ABA_WDS PF02496.11 KEG05962.1 - 0.059 13.5 1.8 0.37 11.0 0.1 2.6 3 0 0 3 3 3 0 ABA/WDS induced protein Spc24 PF08286.6 KEG05962.1 - 0.21 11.2 0.1 0.21 11.2 0.1 1.8 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 Toxin_52 PF15605.1 KEG05963.1 - 1.5 8.7 6.6 3.3 7.6 0.4 3.4 3 1 0 3 3 3 0 Putative toxin 52 ELO PF01151.13 KEG05964.1 - 2.7e-49 167.7 14.4 3.9e-49 167.2 10.0 1.2 1 0 0 1 1 1 1 GNS1/SUR4 family HMG_box_2 PF09011.5 KEG05965.1 - 0.00037 20.8 7.9 0.052 13.9 0.1 2.7 1 1 1 2 2 2 2 HMG-box domain YABBY PF04690.8 KEG05965.1 - 0.0009 19.5 1.1 0.001 19.3 0.8 1.2 1 0 0 1 1 1 1 YABBY protein DUF3106 PF11304.3 KEG05965.1 - 0.01 16.2 3.1 0.01 16.2 2.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3106) HMG_box PF00505.14 KEG05965.1 - 0.098 12.9 4.5 2.3 8.5 0.1 2.8 2 2 0 2 2 2 0 HMG (high mobility group) box S1FA PF04689.8 KEG05965.1 - 3.6 7.5 6.3 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 DNA binding protein S1FA HMG_box_2 PF09011.5 KEG05966.1 - 0.047 14.0 5.6 1.4 9.3 0.0 3.4 3 0 0 3 3 3 0 HMG-box domain Iso_dh PF00180.15 KEG05967.1 - 2.8e-68 230.4 0.0 3.2e-68 230.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Porphobil_deamC PF03900.10 KEG05967.1 - 0.096 12.8 0.1 11 6.2 0.0 2.7 2 0 0 2 2 2 0 Porphobilinogen deaminase, C-terminal domain HEAT PF02985.17 KEG05968.1 - 3.3e-21 73.4 14.3 0.00059 19.7 0.0 10.7 10 0 0 10 10 10 8 HEAT repeat HEAT_2 PF13646.1 KEG05968.1 - 5.7e-17 61.7 6.8 0.0013 18.9 0.0 7.0 3 2 5 8 8 8 7 HEAT repeats HEAT_EZ PF13513.1 KEG05968.1 - 0.0017 18.7 7.8 21 5.7 0.1 6.4 5 1 3 8 8 8 2 HEAT-like repeat Pkinase PF00069.20 KEG05970.1 - 1.5e-34 119.3 0.0 1.8e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG05970.1 - 4.1e-14 52.2 0.0 5e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEG05970.1 - 1.7e-06 27.9 0.1 0.00023 20.9 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 KEG05970.1 - 0.0015 17.6 0.0 0.0035 16.4 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KEG05970.1 - 0.044 13.1 0.0 0.073 12.4 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Peptidase_M8 PF01457.11 KEG05971.1 - 1.2e-99 334.0 5.8 3.5e-54 184.0 0.7 2.1 2 0 0 2 2 2 2 Leishmanolysin Reprolysin_5 PF13688.1 KEG05971.1 - 0.0046 16.9 0.1 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M57 PF12388.3 KEG05971.1 - 0.0047 16.2 0.1 0.0047 16.2 0.1 2.0 2 0 0 2 2 2 1 Dual-action HEIGH metallo-peptidase Astacin PF01400.19 KEG05971.1 - 0.069 12.5 0.1 0.17 11.2 0.1 1.6 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Neuromodulin PF06614.6 KEG05971.1 - 0.12 12.2 9.1 0.23 11.3 6.3 1.4 1 0 0 1 1 1 0 Neuromodulin DUF3479 PF11965.3 KEG05972.1 - 0.0063 16.3 3.4 0.0096 15.7 0.3 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3479) AAA_13 PF13166.1 KEG05972.1 - 0.64 8.4 8.1 1.3 7.4 3.7 2.0 1 1 1 2 2 2 0 AAA domain PFU PF09070.6 KEG05974.1 - 0.16 12.0 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) SSP160 PF06933.6 KEG05974.1 - 0.3 9.0 3.7 0.37 8.7 2.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.7 KEG05974.1 - 0.56 7.8 3.7 0.73 7.5 2.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ras PF00071.17 KEG05975.1 - 1.7e-52 177.1 0.0 1.9e-52 176.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEG05975.1 - 1.3e-17 64.3 0.0 2e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEG05975.1 - 8.3e-11 41.4 0.0 9.6e-11 41.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF258 PF03193.11 KEG05975.1 - 9e-06 24.9 0.0 2.1e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KEG05975.1 - 2e-05 24.7 0.0 3.4e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEG05975.1 - 2.5e-05 24.3 0.0 0.00018 21.5 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 KEG05975.1 - 4.4e-05 23.4 0.0 6.5e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.7 KEG05975.1 - 0.0002 21.0 0.0 0.00032 20.3 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Gtr1_RagA PF04670.7 KEG05975.1 - 0.00052 19.2 0.0 0.00077 18.6 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.22 KEG05975.1 - 0.0035 17.6 0.0 0.0071 16.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SRPRB PF09439.5 KEG05975.1 - 0.0052 16.0 0.0 0.0067 15.6 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.1 KEG05975.1 - 0.0062 16.1 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.13 KEG05975.1 - 0.0075 15.5 0.0 0.21 10.8 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_18 PF13238.1 KEG05975.1 - 0.0077 16.5 0.0 0.061 13.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 KEG05975.1 - 0.009 15.4 0.0 0.28 10.6 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 KEG05975.1 - 0.012 15.1 0.1 0.029 13.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 KEG05975.1 - 0.017 14.8 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.9 KEG05975.1 - 0.018 14.0 0.0 0.045 12.7 0.0 1.6 1 1 0 1 1 1 0 KAP family P-loop domain DUF815 PF05673.8 KEG05975.1 - 0.023 13.6 0.0 0.041 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PduV-EutP PF10662.4 KEG05975.1 - 0.032 13.7 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation PRK PF00485.13 KEG05975.1 - 0.039 13.5 0.0 0.082 12.4 0.0 1.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.17 KEG05975.1 - 0.054 13.6 0.0 0.098 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.21 KEG05975.1 - 0.067 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_32 PF13654.1 KEG05975.1 - 0.072 11.7 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KEG05975.1 - 0.076 12.4 0.0 0.076 12.4 0.0 1.4 1 1 0 1 1 1 0 AAA-like domain G-alpha PF00503.15 KEG05975.1 - 0.098 11.3 0.2 5.2 5.6 0.1 2.3 1 1 1 2 2 2 0 G-protein alpha subunit Hpr_kinase_C PF07475.7 KEG05975.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain Septin PF00735.13 KEG05975.1 - 0.13 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Septin Sec3_C PF09763.4 KEG05976.1 - 5e-47 160.4 0.0 6.3e-47 160.1 0.0 1.2 1 1 0 1 1 1 1 Exocyst complex component Sec3 Tombus_P19 PF03220.8 KEG05977.1 - 0.062 12.6 0.2 0.11 11.8 0.2 1.4 1 0 0 1 1 1 0 Tombusvirus P19 core protein DUF3906 PF13046.1 KEG05977.1 - 0.12 12.0 0.3 0.27 10.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3906) Ctr PF04145.10 KEG05979.1 - 0.00021 21.3 0.1 0.00063 19.8 0.0 2.0 1 1 0 1 1 1 1 Ctr copper transporter family Serinc PF03348.10 KEG05979.1 - 9.6 4.7 13.5 0.089 11.4 0.2 2.6 3 0 0 3 3 3 0 Serine incorporator (Serinc) YdfA_immunity PF12127.3 KEG05980.1 - 0.08 11.8 0.1 0.096 11.5 0.1 1.0 1 0 0 1 1 1 0 SigmaW regulon antibacterial COX17 PF05051.8 KEG05980.1 - 0.15 12.1 3.8 0.11 12.4 1.0 2.1 1 1 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Mucin PF01456.12 KEG05983.1 - 0.0028 17.4 2.4 0.0047 16.7 0.2 2.1 2 0 0 2 2 2 1 Mucin-like glycoprotein Anophelin PF10731.4 KEG05986.1 - 0.022 14.8 0.1 4.1 7.5 0.0 2.5 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito EF-hand_7 PF13499.1 KEG05987.1 - 1.1e-15 57.5 0.1 1.7e-07 31.2 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KEG05987.1 - 2.1e-15 54.7 0.1 6.4e-06 25.1 0.0 4.0 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 KEG05987.1 - 3.1e-15 54.6 1.2 1.8e-05 24.2 0.0 3.8 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.1 KEG05987.1 - 4.8e-10 38.8 1.2 0.0021 17.6 0.3 3.6 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 KEG05987.1 - 2e-08 33.1 0.6 0.00017 20.7 0.0 3.9 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.1 KEG05987.1 - 0.00067 19.5 0.1 0.0045 16.8 0.0 2.2 2 1 0 2 2 2 1 EF-hand domain KIP1 PF07765.7 KEG05987.1 - 0.15 11.9 0.1 1.1 9.1 0.0 2.2 1 1 1 2 2 2 0 KIP1-like protein Acyl-CoA_dh_N PF02771.11 KEG05988.1 - 2.1e-23 83.0 0.5 2.8e-23 82.6 0.1 1.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_ox_N PF14749.1 KEG05988.1 - 0.02 15.1 0.0 0.041 14.1 0.0 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal Guanylate_cyc PF00211.15 KEG05990.1 - 0.0054 16.1 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain gpUL132 PF11359.3 KEG05990.1 - 0.07 12.4 0.0 0.097 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 Peripla_BP_6 PF13458.1 KEG05991.1 - 9.7e-10 38.3 0.3 1.3e-06 28.0 0.1 2.4 2 0 0 2 2 2 2 Periplasmic binding protein Ribonuc_L-PSP PF01042.16 KEG05991.1 - 0.0082 15.9 0.0 0.3 10.8 0.0 2.5 2 0 0 2 2 2 1 Endoribonuclease L-PSP DUF327 PF03885.8 KEG05991.1 - 0.21 11.3 0.0 3.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF327) Thymidylat_synt PF00303.14 KEG05994.1 - 6.7e-110 366.3 0.0 8.5e-110 365.9 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.14 KEG05994.1 - 2.9e-25 88.7 0.0 4.9e-24 84.7 0.0 2.6 1 1 0 1 1 1 1 Dihydrofolate reductase Nucleoside_tran PF01733.13 KEG05995.1 - 1.2e-30 106.7 0.6 1.2e-30 106.7 0.4 1.6 2 0 0 2 2 2 1 Nucleoside transporter MRAP PF15183.1 KEG05995.1 - 0.13 11.9 3.9 0.51 9.9 0.1 2.6 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family Claudin_2 PF13903.1 KEG05995.1 - 4.6 6.9 13.8 1.5 8.4 2.6 3.4 4 0 0 4 4 4 0 PMP-22/EMP/MP20/Claudin tight junction Rhodanese PF00581.15 KEG05996.1 - 1.4e-22 80.1 0.0 4.6e-11 43.0 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain DUF1930 PF09122.5 KEG05996.1 - 5e-10 39.0 0.2 9.8e-10 38.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1930) DUF1664 PF07889.7 KEG05998.1 - 0.082 12.7 3.2 0.47 10.2 0.5 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) AAA_13 PF13166.1 KEG05998.1 - 0.18 10.2 1.8 0.27 9.6 1.2 1.2 1 0 0 1 1 1 0 AAA domain LPP PF04728.8 KEG05998.1 - 0.27 11.0 7.3 3 7.7 0.0 3.3 4 0 0 4 4 4 0 Lipoprotein leucine-zipper Pox_A_type_inc PF04508.7 KEG05998.1 - 0.39 10.6 4.0 1.6 8.6 0.1 3.3 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Mnd1 PF03962.10 KEG05998.1 - 0.76 9.4 9.9 0.39 10.3 3.1 2.7 1 1 2 3 3 3 0 Mnd1 family GAS PF13851.1 KEG05998.1 - 1.3 8.2 8.9 0.9 8.7 3.9 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Snapin_Pallidin PF14712.1 KEG05998.1 - 1.9 8.8 7.2 2.8 8.2 0.6 3.2 2 2 1 3 3 3 0 Snapin/Pallidin ADK PF00406.17 KEG06002.1 - 2.4e-47 160.5 0.0 2.4e-44 150.8 0.0 2.3 2 0 0 2 2 2 2 Adenylate kinase AAA_18 PF13238.1 KEG06002.1 - 2.1e-13 50.7 0.1 3.2e-09 37.1 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 KEG06002.1 - 2.9e-13 50.6 8.2 7e-11 43.0 0.3 3.2 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KEG06002.1 - 8.6e-12 45.1 0.2 6.1e-08 32.6 0.2 3.2 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KEG06002.1 - 5.7e-07 28.8 0.0 0.0015 17.6 0.0 2.6 2 1 0 2 2 2 2 Zeta toxin ADK_lid PF05191.9 KEG06002.1 - 1.6e-06 27.6 0.2 3.8e-06 26.4 0.1 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid Thymidylate_kin PF02223.12 KEG06002.1 - 0.00019 20.8 0.3 0.59 9.4 0.0 3.0 3 0 0 3 3 3 2 Thymidylate kinase AAA_19 PF13245.1 KEG06002.1 - 0.00054 19.6 0.1 0.88 9.3 0.0 2.9 3 0 0 3 3 3 2 Part of AAA domain FtsK_SpoIIIE PF01580.13 KEG06002.1 - 0.00066 19.2 0.0 2.1 7.7 0.0 2.9 3 0 0 3 3 3 2 FtsK/SpoIIIE family T2SE PF00437.15 KEG06002.1 - 0.002 17.1 0.0 1.9 7.3 0.0 2.7 2 1 1 3 3 3 2 Type II/IV secretion system protein AAA PF00004.24 KEG06002.1 - 0.0022 18.2 0.0 0.16 12.1 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KEG06002.1 - 0.0073 15.3 0.0 0.22 10.5 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KEG06002.1 - 0.0095 15.9 0.0 3.9 7.4 0.0 2.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KEG06002.1 - 0.012 15.7 0.0 2.3 8.3 0.0 2.9 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.10 KEG06002.1 - 0.014 15.0 0.0 4.8 6.8 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA_28 PF13521.1 KEG06002.1 - 0.03 14.2 0.3 4.8 7.1 0.3 3.2 2 1 0 2 2 2 0 AAA domain KTI12 PF08433.5 KEG06002.1 - 0.03 13.5 0.0 1.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_29 PF13555.1 KEG06002.1 - 0.045 13.2 0.0 11 5.6 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain PB1-F2 PF11986.3 KEG06002.1 - 0.077 13.0 0.0 5.3 7.1 0.0 2.9 3 0 0 3 3 3 0 Influenza A Proapoptotic protein AAA_10 PF12846.2 KEG06002.1 - 0.085 12.2 0.0 20 4.4 0.0 2.8 3 0 0 3 3 3 0 AAA-like domain AAA_25 PF13481.1 KEG06002.1 - 0.089 12.1 0.0 13 5.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 KEG06002.1 - 0.14 11.3 0.0 12 4.9 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Mucin PF01456.12 KEG06003.1 - 0.012 15.4 1.2 0.014 15.1 0.8 1.4 1 1 0 1 1 1 0 Mucin-like glycoprotein HTH_Tnp_Mu_2 PF09039.6 KEG06004.1 - 0.035 13.8 0.0 0.088 12.5 0.0 1.6 1 0 0 1 1 1 0 Mu DNA binding, I gamma subdomain DUF3584 PF12128.3 KEG06005.1 - 0.0016 15.9 30.5 0.0018 15.7 21.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) PspB PF06667.7 KEG06005.1 - 0.036 14.0 1.7 0.036 14.0 1.2 2.8 2 1 0 2 2 2 0 Phage shock protein B Metallophos PF00149.23 KEG06008.1 - 0.012 14.9 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase ERM PF00769.14 KEG06010.1 - 0.0092 15.5 3.6 0.34 10.3 0.6 2.1 1 1 1 2 2 2 2 Ezrin/radixin/moesin family Sec23_trunk PF04811.10 KEG06012.1 - 4.2e-43 147.4 0.0 5.9e-43 146.9 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KEG06012.1 - 1.1e-19 69.7 1.6 2.3e-19 68.7 0.4 2.0 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KEG06012.1 - 2e-19 69.8 0.0 3.8e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KEG06012.1 - 0.00085 18.8 0.1 0.0021 17.6 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger VWA_2 PF13519.1 KEG06012.1 - 0.051 13.6 0.0 0.11 12.5 0.0 1.5 1 1 0 1 1 1 0 von Willebrand factor type A domain BNR_3 PF13859.1 KEG06015.1 - 1.1e-79 267.7 0.0 2e-79 266.8 0.0 1.4 1 0 0 1 1 1 1 BNR repeat-like domain BNR_2 PF13088.1 KEG06015.1 - 1.7e-19 70.1 0.3 8.7e-17 61.2 0.0 2.3 1 1 1 2 2 2 2 BNR repeat-like domain Laminin_G_3 PF13385.1 KEG06015.1 - 4.7e-11 43.1 0.2 1.8e-10 41.2 0.0 2.1 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily BNR PF02012.15 KEG06015.1 - 4.6e-06 25.6 9.7 0.059 13.2 0.2 4.9 4 0 0 4 4 4 3 BNR/Asp-box repeat Sialidase PF02973.11 KEG06015.1 - 0.035 13.0 0.0 0.071 12.0 0.0 1.4 1 0 0 1 1 1 0 Sialidase, N-terminal domain Mito_fiss_reg PF05308.6 KEG06017.1 - 0.14 11.5 3.6 0.15 11.4 2.5 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 KEG06017.1 - 1.6 7.9 3.8 1.6 7.9 2.7 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal AhpC-TSA PF00578.16 KEG06018.1 - 2.3e-37 127.4 0.0 3.3e-37 126.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KEG06018.1 - 1.6e-16 60.1 0.0 1.9e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 KEG06018.1 - 4.3e-13 48.6 0.0 7.9e-13 47.8 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin IMD PF08397.6 KEG06021.1 - 0.0008 18.7 6.6 0.0008 18.7 4.6 2.2 1 1 0 1 1 1 1 IRSp53/MIM homology domain Filament PF00038.16 KEG06021.1 - 0.0032 16.9 19.1 0.042 13.3 4.3 3.4 1 1 2 3 3 3 1 Intermediate filament protein Vps51 PF08700.6 KEG06021.1 - 0.0061 16.3 1.3 3.4 7.5 0.0 3.6 3 0 0 3 3 3 1 Vps51/Vps67 DUF1090 PF06476.7 KEG06021.1 - 0.0078 15.8 1.0 0.0078 15.8 0.7 3.0 2 1 2 4 4 4 1 Protein of unknown function (DUF1090) FlaC_arch PF05377.6 KEG06021.1 - 0.049 13.5 0.6 6.7 6.6 0.0 3.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Dna2 PF08696.6 KEG06021.1 - 0.053 12.8 2.0 0.15 11.3 0.0 2.4 2 1 1 4 4 4 0 DNA replication factor Dna2 Reo_sigmaC PF04582.7 KEG06021.1 - 0.053 12.6 0.4 8.3 5.4 0.0 2.5 1 1 2 3 3 3 0 Reovirus sigma C capsid protein MutS_III PF05192.13 KEG06021.1 - 0.12 12.0 8.4 0.11 12.2 4.6 1.8 1 1 0 1 1 1 0 MutS domain III BLOC1_2 PF10046.4 KEG06021.1 - 0.13 12.4 7.3 2.5 8.2 0.6 3.5 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DinB_2 PF12867.2 KEG06021.1 - 0.15 12.3 7.0 0.08 13.2 2.8 2.2 2 1 0 2 2 1 0 DinB superfamily DUF310 PF03750.8 KEG06021.1 - 0.22 11.7 1.9 1.3 9.2 0.2 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF310) Laminin_II PF06009.7 KEG06021.1 - 0.3 10.8 9.4 0.2 11.4 1.2 3.3 1 1 3 4 4 4 0 Laminin Domain II AAA_13 PF13166.1 KEG06021.1 - 0.34 9.3 10.4 0.32 9.3 5.6 1.7 1 1 1 2 2 2 0 AAA domain T2SF PF00482.18 KEG06021.1 - 0.5 10.2 6.0 3.8 7.4 0.6 3.1 3 1 1 4 4 4 0 Type II secretion system (T2SS), protein F MitMem_reg PF13012.1 KEG06021.1 - 0.76 9.8 5.4 0.73 9.9 0.4 3.0 1 1 3 4 4 4 0 Maintenance of mitochondrial structure and function ATP-synt_D PF01813.12 KEG06021.1 - 0.93 9.0 7.4 0.59 9.6 0.4 3.0 3 1 1 4 4 4 0 ATP synthase subunit D Hemerythrin PF01814.18 KEG06021.1 - 0.94 9.6 16.5 0.46 10.6 5.2 3.4 1 1 3 4 4 4 0 Hemerythrin HHE cation binding domain Spc7 PF08317.6 KEG06021.1 - 0.97 8.0 14.9 7.1 5.1 0.9 2.7 1 1 1 2 2 2 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.4 KEG06021.1 - 2.8 7.7 23.5 0.43 10.4 6.4 3.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prominin PF05478.6 KEG06021.1 - 3.2 5.1 4.3 5.7 4.3 2.5 1.8 1 1 1 2 2 2 0 Prominin PMC2NT PF08066.7 KEG06021.1 - 4.4 7.6 9.1 0.82 10.0 0.4 3.4 2 1 2 4 4 4 0 PMC2NT (NUC016) domain IncA PF04156.9 KEG06021.1 - 5.1 6.6 25.9 15 5.1 12.1 2.5 1 1 1 2 2 2 0 IncA protein TMPIT PF07851.8 KEG06021.1 - 7.9 5.4 12.8 8.7 5.3 2.0 2.9 1 1 2 3 3 3 0 TMPIT-like protein MutS_IV PF05190.13 KEG06021.1 - 9.9 6.4 8.5 4.2 7.6 0.3 3.9 4 2 0 4 4 4 0 MutS family domain IV RNase_H PF00075.19 KEG06024.1 - 1.7e-14 54.3 0.0 2.5e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 RNase H TFIIA PF03153.8 KEG06028.1 - 8.5 6.1 9.9 11 5.7 6.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mucin PF01456.12 KEG06029.1 - 0.014 15.1 2.7 0.014 15.1 1.9 2.3 2 1 0 2 2 2 0 Mucin-like glycoprotein DUF4246 PF14033.1 KEG06029.1 - 0.16 10.5 0.5 0.26 9.8 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) HTH_41 PF14502.1 KEG06029.1 - 0.33 10.5 2.1 4 7.1 0.2 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HDV_ag PF01517.13 KEG06029.1 - 0.41 10.3 4.7 0.07 12.8 0.5 1.8 2 0 0 2 2 2 0 Hepatitis delta virus delta antigen Gastrin PF00918.12 KEG06029.1 - 2.9 8.7 5.3 0.91 10.3 0.3 2.4 2 2 0 2 2 2 0 Gastrin/cholecystokinin family Flu_M1_C PF08289.6 KEG06029.1 - 2.9 7.9 6.4 11 6.0 0.4 2.7 1 1 1 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain RHSP PF07999.6 KEG06030.1 - 2.1e-85 286.9 0.3 3e-85 286.4 0.2 1.3 1 0 0 1 1 1 1 Retrotransposon hot spot protein AAA_10 PF12846.2 KEG06030.1 - 0.021 14.2 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Mucin PF01456.12 KEG06032.1 - 0.0014 18.4 0.2 0.0014 18.4 0.1 1.5 2 0 0 2 2 2 1 Mucin-like glycoprotein Mod_r PF07200.8 KEG06032.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Peptidase_M16_C PF05193.16 KEG06033.1 - 2.2e-23 82.8 0.0 3.2e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KEG06033.1 - 1.2e-07 31.6 0.0 2.6e-07 30.4 0.0 1.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Phytochelatin PF05023.9 KEG06034.1 - 0.039 12.9 0.0 0.072 12.0 0.0 1.4 1 0 0 1 1 1 0 Phytochelatin synthase Sugar_tr PF00083.19 KEG06037.1 - 9.8e-103 344.1 40.5 4.6e-101 338.6 28.1 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEG06037.1 - 1.3e-18 66.8 28.1 1.5e-15 56.7 19.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily NfeD PF01957.13 KEG06037.1 - 1 9.4 0.0 1 9.4 0.0 4.5 2 1 4 6 6 6 0 NfeD-like C-terminal, partner-binding DSPc PF00782.15 KEG06038.1 - 1e-22 80.1 0.5 2e-09 37.1 0.3 3.4 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KEG06038.1 - 0.0089 15.3 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KEG06038.1 - 0.082 12.9 1.0 0.15 12.1 0.1 1.9 2 1 0 2 2 2 0 Inositol hexakisphosphate Mucin PF01456.12 KEG06039.1 - 6.8e-06 25.9 14.0 6.8e-06 25.9 9.7 3.7 2 1 1 3 3 3 2 Mucin-like glycoprotein Mucin PF01456.12 KEG06040.1 - 5.2e-09 36.0 9.1 5.2e-09 36.0 6.3 3.2 2 1 1 3 3 3 1 Mucin-like glycoprotein CcdB PF01845.12 KEG06040.1 - 0.089 12.7 0.1 0.27 11.1 0.1 1.8 1 0 0 1 1 1 0 CcdB protein Ferritin PF00210.19 KEG06040.1 - 0.37 10.5 9.9 0.06 13.0 0.6 3.0 2 1 0 3 3 3 0 Ferritin-like domain Hamartin PF04388.7 KEG06040.1 - 1.5 7.3 5.7 2.3 6.7 3.9 1.3 1 1 0 1 1 1 0 Hamartin protein eIF3_N PF09440.5 KEG06040.1 - 2.2 8.4 11.1 4.9 7.3 0.5 3.4 2 1 1 3 3 3 0 eIF3 subunit 6 N terminal domain zf-MYND PF01753.13 KEG06042.1 - 4.7e-09 35.9 16.6 8.6e-09 35.1 11.5 1.5 1 0 0 1 1 1 1 MYND finger PAX PF00292.13 KEG06042.1 - 0.042 13.5 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 'Paired box' domain Mito_fiss_reg PF05308.6 KEG06043.1 - 0.02 14.2 0.3 0.043 13.1 0.2 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator V-SNARE_C PF12352.3 KEG06044.1 - 2.3e-05 24.3 5.7 7.5e-05 22.7 0.5 2.8 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KEG06044.1 - 6.6e-05 22.5 0.5 0.00085 18.9 0.0 2.1 2 0 0 2 2 2 1 Sec20 potato_inhibit PF00280.13 KEG06044.1 - 0.021 14.9 0.0 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 Potato inhibitor I family DUF869 PF05911.6 KEG06044.1 - 0.026 12.7 2.9 0.21 9.7 2.1 1.7 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) BRI3BP PF14965.1 KEG06044.1 - 0.044 13.1 0.1 0.069 12.5 0.1 1.4 1 0 0 1 1 1 0 Negative regulator of p53/TP53 Ribonuc_2-5A PF06479.7 KEG06044.1 - 0.077 12.8 0.6 0.19 11.5 0.2 1.7 1 1 1 2 2 2 0 Ribonuclease 2-5A DUF2203 PF09969.4 KEG06044.1 - 0.084 13.0 0.9 0.22 11.7 0.6 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) ThiS PF02597.15 KEG06044.1 - 0.2 12.1 1.4 39 4.7 0.4 3.0 1 1 1 2 2 2 0 ThiS family Seryl_tRNA_N PF02403.17 KEG06044.1 - 0.23 11.5 2.2 2.1 8.4 1.7 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.6 KEG06044.1 - 0.23 10.0 3.2 0.29 9.7 2.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DIRP PF06584.8 KEG06044.1 - 0.25 11.2 2.0 0.25 11.1 0.1 1.9 1 1 1 2 2 2 0 DIRP DUF1691 PF07950.6 KEG06045.1 - 0.25 11.2 2.9 0.16 11.9 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1691) TIP120 PF08623.5 KEG06046.1 - 6.8 6.2 11.2 0.23 11.0 2.7 2.0 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) DUF4055 PF13264.1 KEG06047.1 - 0.092 12.8 3.4 0.23 11.5 2.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4055) AMP-binding PF00501.23 KEG06049.1 - 6.2e-76 255.4 0.5 1.5e-75 254.2 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme Ank_2 PF12796.2 KEG06053.1 - 9.9e-05 22.6 0.0 0.00016 21.9 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KEG06053.1 - 0.00055 19.9 0.0 1.5 9.2 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat UTP15_C PF09384.5 KEG06053.1 - 0.0025 17.5 0.8 0.042 13.5 0.5 2.2 1 1 0 1 1 1 1 UTP15 C terminal DUF2389 PF09493.5 KEG06053.1 - 0.059 13.6 0.2 13 6.1 0.0 2.6 1 1 1 2 2 2 0 Tryptophan-rich protein (DUF2389) Pox_Ag35 PF03286.9 KEG06053.1 - 0.21 11.0 11.7 0.02 14.4 3.6 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein TLP-20 PF06088.6 KEG06053.1 - 0.38 10.4 3.5 0.62 9.7 0.5 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) PRP21_like_P PF12230.3 KEG06053.1 - 0.39 10.1 13.5 0.19 11.2 6.1 2.0 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein Sigma70_ner PF04546.8 KEG06053.1 - 0.51 9.9 17.6 1.6 8.3 8.7 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region Myc_N PF01056.13 KEG06053.1 - 0.52 9.4 12.9 0.19 10.8 4.9 2.1 2 0 0 2 2 2 0 Myc amino-terminal region BUD22 PF09073.5 KEG06053.1 - 0.84 8.6 14.9 0.42 9.6 6.2 2.1 2 0 0 2 2 2 0 BUD22 DUF688 PF05097.7 KEG06053.1 - 0.97 8.2 7.2 0.27 10.1 1.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF688) Afi1 PF07792.7 KEG06053.1 - 1.2 9.1 6.4 1 9.3 2.1 2.0 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking NOA36 PF06524.7 KEG06053.1 - 4.1 6.5 11.7 1 8.5 4.7 1.9 2 0 0 2 2 2 0 NOA36 protein PBP1_TM PF14812.1 KEG06053.1 - 6.7 7.0 26.5 0.45 10.8 7.2 3.3 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FYDLN_acid PF09538.5 KEG06053.1 - 8.3 7.0 17.6 3.3 8.3 7.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Tim54 PF11711.3 KEG06053.1 - 9.5 4.6 11.8 0.65 8.5 4.5 1.6 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 AAA_13 PF13166.1 KEG06054.1 - 0.15 10.4 4.9 0.2 10.0 3.4 1.2 1 0 0 1 1 1 0 AAA domain Nsp1 PF11501.3 KEG06054.1 - 0.17 11.7 0.7 8.7 6.2 0.0 2.9 2 1 1 3 3 3 0 Non structural protein Nsp1 DUF812 PF05667.6 KEG06054.1 - 0.48 8.8 15.7 0.71 8.3 10.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) SPX PF03105.14 KEG06054.1 - 2.2 8.0 7.3 3.7 7.2 5.1 1.4 1 0 0 1 1 1 0 SPX domain DUF1759 PF03564.10 KEG06054.1 - 3.2 7.5 5.6 2 8.2 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) Erp_C PF06780.6 KEG06054.1 - 6.3 6.6 7.4 10 5.9 0.1 2.3 1 1 1 2 2 2 0 Erp protein C-terminus Fmp27_WPPW PF10359.4 KEG06054.1 - 8.1 4.7 12.2 11 4.3 8.4 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain FAM176 PF14851.1 KEG06055.1 - 0.081 12.5 10.3 8.8 5.9 0.0 3.8 3 0 0 3 3 3 0 FAM176 family CDC27 PF09507.5 KEG06055.1 - 0.26 10.4 19.9 0.34 10.0 13.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Mitofilin PF09731.4 KEG06055.1 - 1.4 7.4 10.5 2 6.9 7.2 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PAT1 PF09770.4 KEG06055.1 - 3.6 5.7 75.1 1.7 6.8 50.0 1.6 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Hid1 PF12722.2 KEG06055.1 - 8.8 3.8 19.3 13 3.2 13.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Glyco_transf_10 PF00852.14 KEG06056.1 - 6.3e-14 51.2 1.4 8.9e-14 50.8 1.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) ATP-grasp_4 PF13535.1 KEG06057.1 - 3.6e-16 59.4 0.0 2.4e-15 56.7 0.0 2.2 1 1 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KEG06057.1 - 2.8e-15 56.2 0.0 4.8e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus SET PF00856.23 KEG06057.1 - 1.2e-06 28.9 0.0 1.3e-05 25.5 0.0 2.5 2 0 0 2 2 2 1 SET domain ATPgrasp_Ter PF15632.1 KEG06057.1 - 0.00028 19.7 0.0 0.44 9.2 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 KEG06057.1 - 0.00036 20.4 0.0 0.0013 18.5 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 KEG06057.1 - 0.00053 19.5 0.0 0.0089 15.5 0.0 2.2 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp PF02222.17 KEG06057.1 - 0.038 13.3 0.0 0.097 12.0 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain GARS_A PF01071.14 KEG06057.1 - 0.07 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CcmD PF04995.9 KEG06059.1 - 0.11 12.2 2.8 0.13 12.0 0.3 2.1 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) DUF3377 PF11857.3 KEG06059.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Yip1 PF04893.12 KEG06060.1 - 9.9e-17 60.9 19.6 1.3e-16 60.6 13.6 1.2 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.7 KEG06060.1 - 1.9e-05 24.3 10.7 2.8e-05 23.8 7.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) YIF1 PF03878.10 KEG06060.1 - 1.1 8.3 4.6 1.8 7.6 3.2 1.4 1 0 0 1 1 1 0 YIF1 DUF4175 PF13779.1 KEG06060.1 - 2.4 5.7 4.2 4.2 4.9 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Bax1-I PF01027.15 KEG06060.1 - 6.4 6.3 21.8 1.5e+02 1.8 15.8 2.1 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 RNase_PH PF01138.16 KEG06061.1 - 1.2e-09 38.6 0.0 1.5e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 DUF1012 PF06241.7 KEG06062.1 - 0.15 11.5 0.1 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1012) AT_hook PF02178.14 KEG06062.1 - 0.71 9.7 3.7 4.6 7.2 0.4 2.9 2 0 0 2 2 2 0 AT hook motif Muted PF14942.1 KEG06063.1 - 0.076 12.8 6.6 0.37 10.6 3.1 2.5 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein NAP PF00956.13 KEG06063.1 - 7.9 5.5 7.5 0.9 8.6 2.0 1.7 2 0 0 2 2 2 0 Nucleosome assembly protein (NAP) Ribosomal_60s PF00428.14 KEG06064.1 - 0.12 12.8 2.8 1.1 9.6 0.2 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein UvrD_C PF13361.1 KEG06065.1 - 1.1e-29 104.0 0.0 2.3e-14 53.6 0.0 2.3 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 KEG06065.1 - 7.2e-21 74.7 0.0 1.4e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 KEG06065.1 - 7e-11 42.1 0.0 3.3e-10 40.0 0.0 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 KEG06065.1 - 1.6e-08 34.3 0.0 0.00063 19.3 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.1 KEG06065.1 - 0.0021 17.4 0.0 0.084 12.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 KEG06065.1 - 0.028 13.6 0.0 0.07 12.3 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.1 KEG06065.1 - 0.044 13.9 0.0 0.22 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF3270 PF11674.3 KEG06066.1 - 1.8 8.5 5.8 0.53 10.3 1.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) DUF3634 PF12321.3 KEG06067.1 - 0.025 14.5 0.1 0.033 14.1 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3634) Epimerase PF01370.16 KEG06068.1 - 3.9e-17 62.4 0.0 4.9e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KEG06068.1 - 3.3e-10 39.3 0.0 4.5e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KEG06068.1 - 2.2e-05 23.5 0.0 0.00042 19.3 0.0 2.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KEG06068.1 - 0.00023 19.9 0.0 0.00032 19.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KEG06068.1 - 0.00045 20.1 0.0 0.0008 19.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KEG06068.1 - 0.0025 16.8 0.0 0.0044 15.9 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 KEG06068.1 - 0.02 14.5 0.0 0.035 13.7 0.0 1.5 1 1 0 1 1 1 0 KR domain LRR_4 PF12799.2 KEG06070.1 - 6e-14 51.2 3.5 0.018 14.6 0.0 5.7 2 2 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG06070.1 - 7.3e-09 35.2 7.6 0.011 15.5 0.4 4.3 2 2 3 5 5 5 4 Leucine rich repeat LRR_6 PF13516.1 KEG06070.1 - 3.1e-08 32.8 9.9 0.0014 18.4 0.0 6.8 10 0 0 10 10 10 2 Leucine Rich repeat LRR_1 PF00560.28 KEG06070.1 - 0.00029 20.4 9.1 34 5.0 0.0 7.5 6 2 1 7 7 7 0 Leucine Rich Repeat LRR_7 PF13504.1 KEG06070.1 - 1.4 9.4 10.6 63 4.4 0.0 6.7 8 1 1 9 9 9 0 Leucine rich repeat Kinesin PF00225.18 KEG06072.1 - 5.2e-44 150.3 0.7 9.6e-44 149.4 0.5 1.5 1 0 0 1 1 1 1 Kinesin motor domain Surfac_D-trimer PF09006.6 KEG06072.1 - 0.015 15.0 0.9 0.015 15.0 0.6 2.4 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation YlqD PF11068.3 KEG06072.1 - 0.064 13.2 0.2 0.064 13.2 0.1 2.8 3 0 0 3 3 3 0 YlqD protein DUF972 PF06156.8 KEG06072.1 - 7.2 7.0 11.1 0.23 11.8 0.9 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF972) Hemerythrin PF01814.18 KEG06073.1 - 0.22 11.6 3.6 2.5 8.2 0.3 2.4 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain His_Phos_2 PF00328.17 KEG06074.1 - 2.4e-07 30.4 0.0 3e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) 3HCDH_N PF02737.13 KEG06075.1 - 2e-49 167.6 0.2 2.7e-49 167.2 0.1 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KEG06075.1 - 4.1e-34 116.8 0.1 1e-33 115.5 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ADH_zinc_N PF00107.21 KEG06075.1 - 0.0025 17.3 0.1 0.011 15.2 0.0 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase SET PF00856.23 KEG06076.1 - 9.1e-11 42.3 0.0 2.6e-10 40.8 0.0 1.6 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 KEG06076.1 - 0.0013 18.5 3.5 0.0013 18.5 2.4 3.5 4 1 0 4 4 4 1 MYND finger zf-Mss51 PF13824.1 KEG06076.1 - 0.0021 17.8 1.9 0.0021 17.8 1.3 2.5 4 0 0 4 4 4 1 Zinc-finger of mitochondrial splicing suppressor 51 DUF676 PF05057.9 KEG06077.1 - 2.5e-10 40.0 0.0 2.3e-09 36.8 0.0 2.0 2 0 0 2 2 2 1 Putative serine esterase (DUF676) CRIC_ras_sig PF10534.4 KEG06080.1 - 0.015 15.2 4.8 1 9.4 0.3 2.7 2 0 0 2 2 2 0 Connector enhancer of kinase suppressor of ras AAA_19 PF13245.1 KEG06080.1 - 0.12 12.1 3.7 0.13 12.0 0.7 2.5 2 1 0 2 2 2 0 Part of AAA domain V-SNARE PF05008.10 KEG06080.1 - 0.85 9.8 12.3 0.14 12.3 2.5 3.1 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DNA_pol_delta_4 PF04081.8 KEG06080.1 - 1.6 9.0 8.7 0.13 12.5 1.2 2.7 2 1 1 3 3 3 0 DNA polymerase delta, subunit 4 Cep57_CLD_2 PF14197.1 KEG06080.1 - 3.7 7.5 19.2 0.43 10.5 7.2 3.1 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 DUF1664 PF07889.7 KEG06080.1 - 5 6.9 16.9 0.16 11.7 1.2 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Spc7 PF08317.6 KEG06080.1 - 7.1 5.1 25.3 0.033 12.8 5.2 2.9 2 1 1 3 3 3 0 Spc7 kinetochore protein FlaC_arch PF05377.6 KEG06080.1 - 7.9 6.4 6.7 9.1 6.2 0.4 3.6 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DeoC PF01791.4 KEG06081.1 - 1.4e-13 50.6 0.4 1.7e-13 50.4 0.3 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase UPF0137 PF03677.8 KEG06081.1 - 0.1 12.1 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) DeoC PF01791.4 KEG06082.1 - 6.3e-43 146.7 5.1 7.3e-43 146.5 3.5 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase HTH_30 PF13556.1 KEG06083.1 - 0.023 14.2 0.1 0.041 13.4 0.1 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Scs3p PF10261.4 KEG06084.1 - 0.022 13.8 0.5 0.025 13.6 0.3 1.1 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM BatD PF13584.1 KEG06084.1 - 0.022 13.3 0.0 0.027 13.0 0.0 1.2 1 0 0 1 1 1 0 Oxygen tolerance ASFV_J13L PF05568.6 KEG06084.1 - 0.041 13.4 0.1 0.056 12.9 0.1 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein WBP-1 PF11669.3 KEG06084.1 - 0.05 13.6 0.0 0.062 13.3 0.0 1.2 1 0 0 1 1 1 0 WW domain-binding protein 1 MFS_1 PF07690.11 KEG06084.1 - 0.061 12.0 0.1 0.073 11.7 0.0 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF1049 PF06305.6 KEG06084.1 - 0.063 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Hydrolase PF00702.21 KEG06087.1 - 1.5e-10 41.8 0.0 2.2e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KEG06087.1 - 1.9e-05 24.3 0.1 2.5e-05 23.9 0.1 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KEG06089.1 - 2e-15 56.0 0.0 3.8e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus E1-E2_ATPase PF00122.15 KEG06089.1 - 6.1e-07 28.7 0.0 9.1e-07 28.1 0.0 1.3 1 0 0 1 1 1 1 E1-E2 ATPase CactinC_cactus PF09732.4 KEG06091.1 - 6.6e-42 142.0 0.6 1.2e-41 141.2 0.4 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Peptidase_M8 PF01457.11 KEG06093.1 - 0.004 15.5 0.1 0.0053 15.1 0.1 1.1 1 0 0 1 1 1 1 Leishmanolysin RHSP PF07999.6 KEG06094.1 - 7.7e-87 291.6 0.4 1.2e-86 291.0 0.3 1.3 1 0 0 1 1 1 1 Retrotransposon hot spot protein Macro_2 PF14519.1 KEG06094.1 - 0.0096 15.0 0.0 0.053 12.6 0.0 1.9 2 0 0 2 2 2 1 Macro-like domain AAA_10 PF12846.2 KEG06094.1 - 0.19 11.1 0.0 1.2 8.5 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain Pap_E4 PF02711.9 KEG06094.1 - 2.8 8.8 7.3 1.2 9.9 2.8 2.1 2 0 0 2 2 2 0 E4 protein Alpha_kinase PF02816.13 KEG06095.1 - 6.2e-61 205.3 0.8 7.8e-61 205.0 0.5 1.1 1 0 0 1 1 1 1 Alpha-kinase family UIM PF02809.15 KEG06095.1 - 0.04 13.4 0.1 0.084 12.4 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin interaction motif Galactosyl_T PF01762.16 KEG06097.1 - 2.7e-06 27.1 0.0 0.26 10.8 0.0 3.6 3 1 0 3 3 3 2 Galactosyltransferase Pkinase PF00069.20 KEG06099.1 - 1.1e-25 90.2 0.2 1.4e-25 89.9 0.1 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG06099.1 - 1.5e-08 34.0 0.0 2.3e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEG06099.1 - 4.6e-05 23.2 0.0 0.00025 20.8 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KEG06099.1 - 0.0029 16.7 0.1 0.0052 15.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KEG06100.1 - 1.5e-26 93.1 0.0 1.8e-26 92.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG06100.1 - 3.2e-09 36.2 0.0 4.4e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KEG06100.1 - 0.005 15.9 0.1 0.015 14.4 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEG06100.1 - 0.092 12.4 0.0 3.9 7.1 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family adh_short PF00106.20 KEG06102.1 - 7e-35 120.4 5.1 8.5e-35 120.1 3.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEG06102.1 - 1.2e-18 67.3 2.9 1.6e-18 67.0 2.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEG06102.1 - 1.1e-15 58.0 0.0 1.4e-15 57.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KEG06102.1 - 1.2e-06 28.6 0.4 4.1e-06 26.9 0.3 1.8 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KEG06102.1 - 8.2e-06 24.9 0.2 1.2e-05 24.3 0.1 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KEG06102.1 - 0.002 17.5 0.7 0.0091 15.4 0.5 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KEG06102.1 - 0.0088 14.7 0.4 0.014 14.1 0.2 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PALP PF00291.20 KEG06102.1 - 0.011 14.9 0.2 0.017 14.3 0.1 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme YjeF_N PF03853.10 KEG06102.1 - 0.05 13.2 0.2 0.072 12.6 0.1 1.2 1 0 0 1 1 1 0 YjeF-related protein N-terminus GSDH PF07995.6 KEG06106.1 - 0.21 10.6 2.6 0.28 10.2 1.4 1.4 1 1 0 1 1 1 0 Glucose / Sorbosone dehydrogenase Optomotor-blind PF11078.3 KEG06107.1 - 0.067 13.5 1.0 0.17 12.2 0.7 1.7 1 0 0 1 1 1 0 Optomotor-blind protein N-terminal region SET PF00856.23 KEG06108.1 - 1.9e-10 41.3 0.1 2.3e-10 40.9 0.1 1.1 1 0 0 1 1 1 1 SET domain Phospholip_B PF04916.8 KEG06109.1 - 3.6e-42 144.2 0.0 4.3e-42 143.9 0.0 1.0 1 0 0 1 1 1 1 Phospholipase B Ion_trans_2 PF07885.11 KEG06109.1 - 0.049 13.3 0.1 0.078 12.7 0.1 1.3 1 0 0 1 1 1 0 Ion channel DUF1191 PF06697.7 KEG06109.1 - 0.075 11.8 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) SURF6 PF04935.7 KEG06116.1 - 2.7e-11 43.1 18.1 2.7e-11 43.1 12.5 2.0 1 1 1 2 2 2 1 Surfeit locus protein 6 PolC_DP2 PF03833.8 KEG06116.1 - 0.035 11.8 0.1 0.036 11.7 0.1 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DUF2785 PF10978.3 KEG06116.1 - 0.061 12.7 0.2 0.078 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2785) Synthase_beta PF11421.3 KEG06116.1 - 0.079 13.6 1.2 0.17 12.5 0.1 2.1 2 0 0 2 2 2 0 ATP synthase F1 beta subunit FUSC PF04632.7 KEG06116.1 - 0.55 8.6 2.4 0.62 8.4 1.7 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Bax1-I PF01027.15 KEG06117.1 - 7e-36 123.7 17.3 1.1e-35 123.1 12.0 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 TCP PF03634.8 KEG06118.1 - 7.7 6.8 24.4 2e+02 2.2 16.9 2.2 1 1 0 1 1 1 0 TCP family transcription factor TMCO5 PF14992.1 KEG06119.1 - 0.0015 17.7 15.4 0.034 13.2 2.3 2.3 1 1 1 2 2 2 2 TMCO5 family V_ATPase_I PF01496.14 KEG06119.1 - 8.9 4.0 7.5 13 3.5 5.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Exo_endo_phos_2 PF14529.1 KEG06120.1 - 1.7e-13 50.1 0.1 2.4e-13 49.7 0.1 1.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase 6PF2K PF01591.13 KEG06121.1 - 5.9e-35 120.3 0.0 9.3e-35 119.6 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase Ank_2 PF12796.2 KEG06121.1 - 3.1e-18 65.9 0.1 9.8e-18 64.2 0.1 1.8 2 0 0 2 2 1 1 Ankyrin repeats (3 copies) His_Phos_1 PF00300.17 KEG06121.1 - 8e-17 61.7 0.0 5.8e-16 58.9 0.0 2.2 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Ank PF00023.25 KEG06121.1 - 4.1e-15 54.7 0.6 8.5e-09 34.7 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KEG06121.1 - 2.7e-14 53.2 0.4 1.9e-07 31.4 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEG06121.1 - 2.8e-12 46.4 0.7 1.8e-11 43.8 0.3 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEG06121.1 - 2.8e-06 27.0 0.0 0.00038 20.4 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat AAA_33 PF13671.1 KEG06121.1 - 3.9e-06 26.7 0.0 8.5e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEG06121.1 - 0.026 15.3 0.0 0.063 14.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KEG06121.1 - 0.04 13.0 0.1 0.2 10.6 0.0 2.0 1 1 0 1 1 1 0 Zeta toxin APS_kinase PF01583.15 KEG06121.1 - 0.049 13.2 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase KTI12 PF08433.5 KEG06121.1 - 0.051 12.7 0.0 0.083 12.0 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_5 PF07728.9 KEG06121.1 - 0.082 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KEG06121.1 - 0.12 12.4 0.0 0.72 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain SchA_CurD PF04486.7 KEG06122.1 - 0.18 11.6 2.5 0.25 11.1 1.7 1.3 1 0 0 1 1 1 0 SchA/CurD like domain HrpE PF06188.7 KEG06122.1 - 0.31 10.7 9.7 1.4 8.6 6.4 1.9 1 1 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E ATP-synt_B PF00430.13 KEG06122.1 - 0.82 9.4 10.1 3.5 7.4 0.5 2.2 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) DUF2611 PF11022.3 KEG06122.1 - 2 8.5 5.7 2.2 8.4 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2611) CK_II_beta PF01214.13 KEG06127.1 - 7e-75 250.5 0.0 8.9e-75 250.2 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit PDEase_I PF00233.14 KEG06128.1 - 9.2e-63 212.1 0.0 1.1e-61 208.6 0.0 1.9 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase TGT PF01702.13 KEG06128.1 - 0.093 11.9 0.2 0.24 10.6 0.0 1.7 2 0 0 2 2 2 0 Queuine tRNA-ribosyltransferase Aminotran_1_2 PF00155.16 KEG06131.1 - 7.9e-34 117.1 0.0 1e-33 116.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II TFIIS_C PF01096.13 KEG06133.1 - 1e-16 60.2 6.7 1.8e-16 59.4 4.6 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.2 KEG06133.1 - 0.011 15.4 1.2 0.024 14.4 0.9 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Elf1 PF05129.8 KEG06133.1 - 0.12 12.0 1.8 0.23 11.1 1.3 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Sgf11 PF08209.6 KEG06133.1 - 0.2 10.9 2.3 0.94 8.8 0.1 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-ribbon_3 PF13248.1 KEG06133.1 - 1.9 7.8 5.2 0.84 8.9 1.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain PWWP PF00855.12 KEG06134.1 - 5.5e-09 36.0 0.7 1.3e-08 34.9 0.0 2.1 3 0 0 3 3 3 1 PWWP domain Med26 PF08711.6 KEG06134.1 - 0.014 14.8 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 TFIIS helical bundle-like domain Herpes_UL3 PF03369.8 KEG06134.1 - 0.055 13.4 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Herpesvirus UL3 protein CDC27 PF09507.5 KEG06134.1 - 0.95 8.6 17.9 1.2 8.2 12.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 START PF01852.14 KEG06135.1 - 1e-05 24.9 0.0 1.6e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 START domain WD40 PF00400.27 KEG06136.1 - 2.1e-11 43.2 1.5 1.6e-08 34.1 1.1 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat Pkinase PF00069.20 KEG06137.1 - 1.6e-75 253.6 0.0 1.8e-75 253.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG06137.1 - 3.8e-37 127.7 0.0 4.7e-37 127.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG06137.1 - 3.8e-08 32.6 0.0 2.6e-07 29.8 0.0 1.9 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.17 KEG06137.1 - 3e-05 23.4 0.0 5.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KEG06137.1 - 0.0019 17.3 0.2 0.0029 16.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEG06137.1 - 0.022 14.5 0.1 0.91 9.2 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family XRCC4 PF06632.7 KEG06140.1 - 0.032 13.1 0.0 0.037 12.8 0.0 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 zf-RING_5 PF14634.1 KEG06142.1 - 7.2e-06 25.6 14.9 1.1e-05 25.0 10.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KEG06142.1 - 0.038 14.0 17.8 0.059 13.4 12.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEG06142.1 - 0.09 12.6 15.0 0.16 11.7 10.4 1.5 1 0 0 1 1 1 0 Ring finger domain Chlamy_scaf PF09675.5 KEG06142.1 - 0.097 12.6 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) zf-C3HC4 PF00097.20 KEG06142.1 - 0.12 12.0 13.5 0.22 11.1 9.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PolC_DP2 PF03833.8 KEG06142.1 - 0.42 8.2 2.6 0.39 8.3 1.8 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-RING_6 PF14835.1 KEG06142.1 - 2.1 8.1 11.2 24 4.8 7.7 2.1 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Fer2_3 PF13085.1 KEG06142.1 - 2.7 7.8 5.2 2.5 7.9 1.9 1.9 1 1 1 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain DUF4200 PF13863.1 KEG06143.1 - 1.9e-26 92.4 19.5 1.9e-26 92.4 13.5 2.6 3 0 0 3 3 3 2 Domain of unknown function (DUF4200) DUF1043 PF06295.7 KEG06143.1 - 0.007 16.0 2.1 0.007 16.0 1.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1043) Tetrabrachion PF11401.3 KEG06143.1 - 0.13 12.1 0.1 0.33 10.7 0.0 1.7 2 0 0 2 2 2 0 Tetrabrachion Rootletin PF15035.1 KEG06143.1 - 0.41 10.5 37.4 2 8.3 10.7 2.7 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion M_domain PF12938.2 KEG06143.1 - 0.51 10.1 7.6 1.2 8.9 5.3 1.6 1 0 0 1 1 1 0 M domain of GW182 RNA_replicase_B PF03431.8 KEG06143.1 - 2.4 6.2 12.2 0.027 12.6 1.5 2.0 1 1 1 2 2 2 0 RNA replicase, beta-chain DUF948 PF06103.6 KEG06143.1 - 4.7 7.1 7.7 2.1 8.2 0.4 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DASH_Spc34 PF08657.5 KEG06143.1 - 5.7 6.5 36.2 0.24 11.0 7.0 3.5 3 1 1 4 4 4 0 DASH complex subunit Spc34 DUF342 PF03961.8 KEG06143.1 - 6.1 5.1 18.8 0.11 10.8 5.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Tryp_alpha_amyl PF00234.17 KEG06145.1 - 0.15 12.2 1.5 0.18 12.0 1.1 1.3 1 1 0 1 1 1 0 Protease inhibitor/seed storage/LTP family Pacs-1 PF10254.4 KEG06146.1 - 0.021 13.4 0.1 0.032 12.8 0.1 1.2 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein GTP_EFTU_D3 PF03143.12 KEG06147.1 - 7.3e-20 70.9 0.1 1.8e-19 69.7 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU PF00009.22 KEG06147.1 - 4.5e-14 52.3 0.0 1.5e-13 50.5 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 KEG06147.1 - 1.2e-05 25.2 0.9 3.3e-05 23.9 0.2 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 60KD_IMP PF02096.15 KEG06148.1 - 3e-29 102.0 0.1 4.3e-29 101.5 0.1 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein Leu_zip PF15294.1 KEG06149.1 - 0.023 13.8 0.1 0.029 13.4 0.0 1.1 1 0 0 1 1 1 0 Leucine zipper DUF4630 PF15443.1 KEG06149.1 - 0.06 13.1 2.2 0.079 12.7 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4630) SOG2 PF10428.4 KEG06150.1 - 1.5 7.4 4.8 1.5 7.3 3.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF647 PF04884.9 KEG06152.1 - 0.0077 15.4 0.1 0.0082 15.3 0.0 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis DUF3474 PF11960.3 KEG06152.1 - 0.032 14.2 0.0 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) Glycos_transf_1 PF00534.15 KEG06153.1 - 1.4e-13 50.6 0.0 8.2e-13 48.1 0.0 2.2 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KEG06153.1 - 2.7e-08 34.0 0.1 9.7e-08 32.2 0.1 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KEG06153.1 - 8e-07 29.2 0.1 1.1e-05 25.5 0.0 2.5 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glycogen_syn PF05693.8 KEG06153.1 - 0.0046 15.2 0.0 0.0064 14.7 0.0 1.2 1 0 0 1 1 1 1 Glycogen synthase Geminin PF07412.7 KEG06153.1 - 0.036 13.7 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 Geminin Glyco_trans_4_4 PF13579.1 KEG06153.1 - 0.12 12.4 3.3 0.57 10.3 0.0 3.0 3 2 0 3 3 3 0 Glycosyl transferase 4-like domain Cpn60_TCP1 PF00118.19 KEG06154.1 - 1.4e-149 498.8 5.8 1.6e-149 498.6 4.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Fumerase_C PF05683.7 KEG06154.1 - 0.0098 15.0 0.1 0.079 12.0 0.0 2.2 2 0 0 2 2 2 1 Fumarase C-terminus DUF3673 PF12425.3 KEG06155.1 - 2.5 8.0 7.1 1.1 9.1 1.7 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3673) VPS11_C PF12451.3 KEG06156.1 - 7.8e-08 32.0 0.4 2.3e-07 30.5 0.3 1.8 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal PYST-C1 PF09690.5 KEG06156.1 - 0.029 14.0 1.6 0.05 13.2 1.1 1.3 1 0 0 1 1 1 0 Plasmodium yoelii subtelomeric region (PYST-C1) zf-RING_6 PF14835.1 KEG06156.1 - 0.03 14.1 1.7 0.03 14.1 1.2 1.6 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.1 KEG06156.1 - 0.05 13.6 8.6 0.13 12.3 6.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEG06156.1 - 0.13 12.0 10.3 0.3 10.8 7.1 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.2 KEG06156.1 - 0.2 11.8 5.7 0.45 10.6 3.9 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger Prok-RING_1 PF14446.1 KEG06156.1 - 0.24 11.1 6.4 0.59 9.9 4.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-Apc11 PF12861.2 KEG06156.1 - 0.27 11.1 2.9 0.66 9.8 2.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 KEG06156.1 - 0.49 10.2 12.4 0.49 10.2 7.5 1.9 2 0 0 2 2 2 0 Ring finger domain Acyl-CoA_dh_1 PF00441.19 KEG06159.1 - 9.8e-26 90.6 2.2 1.4e-25 90.1 1.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KEG06159.1 - 8.5e-10 38.0 0.1 1.9e-09 36.9 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KEG06159.1 - 1.7e-09 38.0 1.3 2.8e-09 37.3 0.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Actin PF00022.14 KEG06160.1 - 1.1e-38 132.6 0.0 1.6e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Actin Fanconi_C PF02106.10 KEG06160.1 - 0.11 10.9 0.0 0.17 10.2 0.0 1.2 1 0 0 1 1 1 0 Fanconi anaemia group C protein SPRY PF00622.23 KEG06161.1 - 2e-06 27.9 0.0 3.3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 SPRY domain Myosin_tail_1 PF01576.14 KEG06161.1 - 0.12 10.0 26.1 0.19 9.4 18.1 1.2 1 0 0 1 1 1 0 Myosin tail Mnd1 PF03962.10 KEG06161.1 - 0.55 9.8 13.8 1.4 8.5 9.6 1.7 1 0 0 1 1 1 0 Mnd1 family ATP-gua_PtransN PF02807.10 KEG06163.1 - 7.2e-36 122.1 0.1 1e-35 121.6 0.1 1.3 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain DUF3420 PF11900.3 KEG06163.1 - 0.023 14.7 1.2 0.54 10.3 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3420) Ax_dynein_light PF10211.4 KEG06165.1 - 1.1e-54 185.1 4.2 1.5e-54 184.7 2.9 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain DUF4127 PF13552.1 KEG06165.1 - 0.013 13.9 1.0 0.018 13.4 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4127) DUF4635 PF15466.1 KEG06165.1 - 0.019 14.2 3.5 0.022 14.0 1.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4635) IncA PF04156.9 KEG06165.1 - 0.031 13.8 8.0 0.055 13.0 5.5 1.3 1 0 0 1 1 1 0 IncA protein DUF4472 PF14739.1 KEG06165.1 - 0.036 14.5 4.4 0.071 13.5 3.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) LcrG PF07216.7 KEG06165.1 - 0.042 13.8 4.1 0.68 9.9 0.2 2.6 1 1 1 2 2 2 0 LcrG protein bZIP_2 PF07716.10 KEG06165.1 - 0.046 13.5 11.5 0.79 9.5 0.8 2.6 2 0 0 2 2 2 0 Basic region leucine zipper Seryl_tRNA_N PF02403.17 KEG06165.1 - 0.075 13.0 7.3 0.15 12.1 5.1 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF2317 PF10079.4 KEG06165.1 - 0.077 11.5 4.8 0.096 11.2 3.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) PA26 PF04636.8 KEG06165.1 - 0.099 11.3 1.9 0.12 10.9 1.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF2935 PF11155.3 KEG06165.1 - 0.37 10.8 3.4 0.81 9.7 2.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) FlaC_arch PF05377.6 KEG06165.1 - 0.46 10.4 3.3 1.6 8.7 2.3 2.0 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) Lzipper-MIP1 PF14389.1 KEG06165.1 - 0.57 10.3 6.1 3 8.0 0.3 2.7 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Fib_alpha PF08702.5 KEG06165.1 - 1.8 8.6 5.4 5.6 7.0 3.0 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Cauli_AT PF03233.8 KEG06165.1 - 2.5 7.7 5.3 5.1 6.7 3.2 1.6 1 1 1 2 2 2 0 Aphid transmission protein DUF737 PF05300.6 KEG06165.1 - 3.6 7.5 12.2 1.2 9.0 4.6 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF737) WD40_alt PF14077.1 KEG06165.1 - 5.7 6.6 9.3 3.2 7.4 0.7 2.5 2 0 0 2 2 2 0 Alternative WD40 repeat motif RNase_H PF00075.19 KEG06166.1 - 2.6e-13 50.4 0.0 4.1e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 RNase H Peripla_BP_6 PF13458.1 KEG06170.1 - 3.2e-08 33.2 0.0 4.1e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein DDHD PF02862.12 KEG06171.1 - 0.22 11.2 2.3 0.24 11.1 1.6 1.1 1 0 0 1 1 1 0 DDHD domain TFIIF_alpha PF05793.7 KEG06171.1 - 0.86 7.8 0.0 0.86 7.8 0.0 2.0 1 1 1 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) HAUS6_N PF14661.1 KEG06171.1 - 3.8 6.8 6.7 3.8 6.8 4.7 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus S-antigen PF05756.6 KEG06171.1 - 9.5 6.2 15.2 1.9 8.4 3.7 2.1 2 0 0 2 2 2 0 S-antigen protein TerB PF05099.8 KEG06172.1 - 0.061 13.0 0.8 0.085 12.5 0.6 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TerB TAF1D PF15333.1 KEG06176.1 - 0.85 9.3 9.5 0.2 11.4 3.8 1.9 2 0 0 2 2 2 0 TATA box-binding protein-associated factor 1D Metallophos PF00149.23 KEG06177.1 - 1.4e-35 122.5 1.2 1.6e-35 122.2 0.1 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase zf-TRAF PF02176.13 KEG06177.1 - 0.0012 19.2 4.8 0.0012 19.2 3.3 1.8 1 1 0 1 1 1 1 TRAF-type zinc finger Metallophos_2 PF12850.2 KEG06177.1 - 0.0036 17.1 0.0 0.0061 16.4 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain EF-hand_6 PF13405.1 KEG06177.1 - 0.0045 16.7 0.0 0.76 9.8 0.0 3.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 KEG06177.1 - 0.022 14.0 0.3 1.3 8.4 0.0 3.5 4 0 0 4 4 4 0 EF hand DZR PF12773.2 KEG06177.1 - 3.5 7.5 9.2 7.7 6.4 6.4 1.6 1 0 0 1 1 1 0 Double zinc ribbon E1-E2_ATPase PF00122.15 KEG06179.1 - 1.2e-45 155.3 1.9 2.5e-45 154.3 1.4 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KEG06179.1 - 6.1e-41 141.1 4.7 1.3e-40 140.1 3.3 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KEG06179.1 - 6e-23 80.7 0.7 3e-10 40.0 0.2 2.7 2 0 0 2 2 2 2 Heavy-metal-associated domain HAD PF12710.2 KEG06179.1 - 9.4e-16 58.5 0.0 1.9e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KEG06179.1 - 1.7e-07 31.0 0.0 3.2e-06 26.9 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Mucin PF01456.12 KEG06180.1 - 1.3e-07 31.5 44.7 4.2e-05 23.3 6.3 3.4 1 1 1 3 3 3 2 Mucin-like glycoprotein DUF1223 PF06764.6 KEG06180.1 - 5.7 6.6 10.2 0.12 12.1 0.9 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1223) DUF3906 PF13046.1 KEG06181.1 - 0.2 11.2 3.4 0.18 11.4 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3906) Muted PF14942.1 KEG06182.1 - 3.8 7.3 8.7 1.5 8.6 0.0 2.7 3 0 0 3 3 3 0 Organelle biogenesis, Muted-like protein DUF972 PF06156.8 KEG06182.1 - 9 6.7 8.7 1.7 9.0 1.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF972) p25-alpha PF05517.7 KEG06183.1 - 3.9e-47 160.3 3.6 4.6e-47 160.1 2.5 1.0 1 0 0 1 1 1 1 p25-alpha FtsH_ext PF06480.10 KEG06183.1 - 0.01 16.0 0.1 0.034 14.3 0.1 1.9 1 1 1 2 2 2 0 FtsH Extracellular PQQ_2 PF13360.1 KEG06184.1 - 0.041 13.3 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 PQQ-like domain SKG6 PF08693.5 KEG06184.1 - 0.065 12.5 2.8 0.19 11.1 1.9 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain QueT PF06177.6 KEG06185.1 - 0.0084 16.0 4.4 0.0084 16.0 3.0 1.9 1 1 0 2 2 2 1 QueT transporter DUF1129 PF06570.6 KEG06185.1 - 0.22 10.8 1.5 0.33 10.2 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF2633 PF11119.3 KEG06185.1 - 0.29 10.8 1.6 0.4 10.4 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) DUF4149 PF13664.1 KEG06185.1 - 1.5 8.9 10.4 4.9 7.2 1.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) MFS_1 PF07690.11 KEG06186.1 - 2.4e-16 59.4 22.8 2.7e-16 59.2 15.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.8 KEG06186.1 - 9.4e-05 21.7 14.5 0.0013 18.0 10.0 2.2 1 1 0 1 1 1 1 Nodulin-like OppC_N PF12911.2 KEG06186.1 - 9.4 5.6 10.7 15 5.0 0.2 3.6 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C Herpes_UL52 PF03121.10 KEG06188.1 - 8.7e-14 51.0 0.1 1.8e-13 49.9 0.1 1.6 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase zf-ISL3 PF14690.1 KEG06190.1 - 0.56 10.2 5.0 0.17 11.9 1.1 2.0 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 ADK_lid PF05191.9 KEG06190.1 - 0.91 9.2 4.6 4.9 6.8 3.2 2.3 1 1 0 1 1 1 0 Adenylate kinase, active site lid RXT2_N PF08595.6 KEG06191.1 - 0.32 10.7 3.0 0.47 10.2 2.1 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal PBP1_TM PF14812.1 KEG06191.1 - 0.35 11.1 7.4 0.73 10.1 5.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Myc_N PF01056.13 KEG06191.1 - 0.88 8.6 3.1 1.2 8.2 2.1 1.2 1 0 0 1 1 1 0 Myc amino-terminal region FAM177 PF14774.1 KEG06191.1 - 5.6 6.8 7.0 2.4 8.0 0.0 2.2 1 1 1 2 2 2 0 FAM177 family Di19_C PF14571.1 KEG06192.1 - 0.019 15.2 9.9 0.49 10.7 0.1 2.6 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal PHD PF00628.24 KEG06192.1 - 0.35 10.5 9.5 0.93 9.2 6.6 1.8 1 1 0 1 1 1 0 PHD-finger SPT6_acidic PF14632.1 KEG06192.1 - 1.4 9.0 8.6 0.048 13.8 1.4 1.9 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Gly_kinase PF02595.10 KEG06194.1 - 6.3e-07 28.4 0.0 8.2e-07 28.0 0.0 1.1 1 0 0 1 1 1 1 Glycerate kinase family BAF1_ABF1 PF04684.8 KEG06195.1 - 2.1 7.0 8.6 0.24 10.1 1.7 2.2 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor ELO PF01151.13 KEG06196.1 - 1.1e-79 267.3 25.6 1.3e-79 267.0 17.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Vma12 PF11712.3 KEG06196.1 - 0.25 11.0 0.0 0.25 11.0 0.0 2.3 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF4592 PF15262.1 KEG06197.1 - 4.6 7.7 11.3 18 5.8 4.2 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4592) HECT PF00632.20 KEG06198.1 - 6.5e-92 308.0 0.0 9.6e-92 307.5 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RRN7 PF11781.3 KEG06198.1 - 0.26 10.7 2.4 0.35 10.3 0.3 2.2 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Nop PF01798.13 KEG06199.1 - 1.3e-55 186.8 0.1 1.3e-55 186.8 0.0 1.8 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 KEG06199.1 - 2.3e-21 75.3 0.0 4.8e-21 74.3 0.0 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KEG06199.1 - 1.1e-19 70.3 0.0 3.1e-19 68.9 0.0 1.8 1 0 0 1 1 1 1 NOP5NT (NUC127) domain zf-Tim10_DDP PF02953.10 KEG06202.1 - 4.8e-05 22.5 0.1 6e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Pkinase PF00069.20 KEG06203.1 - 2.8e-29 102.0 0.0 1.8e-28 99.4 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG06203.1 - 0.0079 15.2 0.0 1.5 7.8 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 KEG06203.1 - 0.032 13.2 0.0 0.053 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KEG06203.1 - 0.19 10.4 0.0 0.27 9.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase FlgD PF03963.9 KEG06204.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Flagellar hook capping protein - N-terminal region TadE PF07811.7 KEG06205.1 - 2.6 8.0 4.2 4.6 7.2 2.9 1.4 1 0 0 1 1 1 0 TadE-like protein SLX9 PF15341.1 KEG06208.1 - 0.00011 22.6 11.9 0.00011 22.6 8.3 2.5 2 1 0 2 2 2 1 Ribosome biogenesis protein SLX9 DUF3698 PF12479.3 KEG06208.1 - 0.17 11.9 1.6 0.29 11.2 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3698) Endomucin PF07010.7 KEG06208.1 - 0.19 11.0 1.3 0.27 10.5 0.9 1.3 1 0 0 1 1 1 0 Endomucin SLD3 PF08639.5 KEG06208.1 - 4.9 5.6 18.9 5.7 5.4 13.1 1.0 1 0 0 1 1 1 0 DNA replication regulator SLD3 Abhydrolase_6 PF12697.2 KEG06209.1 - 4e-29 102.1 4.0 6e-29 101.5 2.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEG06209.1 - 1.3e-21 77.2 0.1 7.2e-12 45.3 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEG06209.1 - 4.1e-13 49.3 1.0 3.3e-11 43.1 0.7 2.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 KEG06209.1 - 5.4e-06 26.2 0.0 1.2e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein DLH PF01738.13 KEG06209.1 - 1.8e-05 24.1 0.0 0.033 13.4 0.0 2.4 2 0 0 2 2 2 2 Dienelactone hydrolase family Esterase_phd PF10503.4 KEG06209.1 - 0.00043 19.6 0.7 0.0051 16.0 0.3 2.3 2 0 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.11 KEG06209.1 - 0.0032 16.9 0.0 0.021 14.2 0.0 2.0 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Ndr PF03096.9 KEG06209.1 - 0.0042 15.5 0.0 0.0068 14.9 0.0 1.2 1 0 0 1 1 1 1 Ndr family Esterase PF00756.15 KEG06209.1 - 0.0066 15.9 0.3 0.011 15.1 0.2 1.3 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.3 KEG06209.1 - 0.0079 16.0 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 KEG06209.1 - 0.011 16.0 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DUF2048 PF09752.4 KEG06209.1 - 0.012 14.5 0.5 0.028 13.2 0.4 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) LRR_8 PF13855.1 KEG06210.1 - 1e-07 31.5 4.4 0.015 15.0 2.3 3.5 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KEG06210.1 - 1.3e-07 31.1 6.8 0.012 15.2 5.6 3.8 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KEG06210.1 - 4.3e-07 29.3 4.3 0.026 14.5 0.1 3.6 3 0 0 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.28 KEG06210.1 - 0.00015 21.3 3.8 0.35 11.0 0.1 3.9 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_7 PF13504.1 KEG06210.1 - 0.0038 17.1 3.2 4.4 7.9 0.1 3.9 3 0 0 3 3 3 2 Leucine rich repeat LRR_9 PF14580.1 KEG06210.1 - 0.07 12.6 0.2 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Leucine-rich repeat RhoGEF PF00621.15 KEG06211.1 - 1.6e-06 28.0 0.0 6.5e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 RhoGEF domain PDEase_I PF00233.14 KEG06213.1 - 1.9e-16 60.5 0.2 1.9e-16 60.5 0.1 2.0 2 1 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase SRP-alpha_N PF04086.8 KEG06215.1 - 0.23 10.8 0.9 0.41 9.9 0.6 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DBI_PRT PF02277.12 KEG06216.1 - 0.044 12.8 2.5 0.32 10.0 0.0 2.6 3 0 0 3 3 3 0 Phosphoribosyltransferase TPR_11 PF13414.1 KEG06218.1 - 8.5e-07 28.5 7.7 1.2e-05 24.8 1.2 2.2 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 KEG06218.1 - 5e-05 22.9 5.1 0.99 9.4 0.0 3.9 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEG06218.1 - 0.00027 21.5 14.4 0.002 18.7 5.7 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEG06218.1 - 0.00071 19.9 12.1 0.097 13.3 0.8 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 KEG06218.1 - 0.00075 19.7 2.2 0.83 10.2 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KEG06218.1 - 0.0014 18.5 5.8 0.0032 17.3 2.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 KEG06218.1 - 0.0034 17.4 4.1 0.0093 16.1 0.0 3.3 3 1 0 3 3 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEG06218.1 - 0.0061 16.8 1.3 4.9 7.5 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 KEG06218.1 - 0.01 15.7 7.2 0.045 13.6 0.6 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 KEG06218.1 - 0.04 14.3 0.1 0.04 14.3 0.0 3.7 5 0 0 5 5 3 0 Tetratricopeptide repeat Rapsyn_N PF10579.4 KEG06218.1 - 0.063 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region DUF4398 PF14346.1 KEG06218.1 - 0.091 12.8 0.6 0.33 11.0 0.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4398) TPR_9 PF13371.1 KEG06218.1 - 1.8 8.4 9.5 0.24 11.2 2.5 2.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KEG06218.1 - 2.3 8.2 7.3 7 6.7 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DNA_pol_viral_N PF00242.12 KEG06219.1 - 0.1 11.6 3.1 0.11 11.4 2.2 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Mucin PF01456.12 KEG06220.1 - 1.7e-08 34.3 53.5 0.0016 18.1 19.9 3.5 1 1 1 2 2 2 2 Mucin-like glycoprotein UPF0556 PF10572.4 KEG06220.1 - 0.055 12.6 1.4 0.12 11.5 0.1 2.4 3 1 0 3 3 3 0 Uncharacterised protein family UPF0556 DUF4189 PF13827.1 KEG06220.1 - 3.1 8.1 7.8 9.1 6.5 0.2 3.2 2 1 0 3 3 3 0 Domain of unknown function (DUF4189) Mucin PF01456.12 KEG06221.1 - 2.2e-07 30.7 1.2 2.7e-07 30.4 0.8 1.1 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF1455 PF07306.6 KEG06221.1 - 0.17 11.9 1.4 0.19 11.7 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1455) UBN2 PF14223.1 KEG06222.1 - 0.0014 18.4 0.3 0.0025 17.6 0.2 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UPF0449 PF15136.1 KEG06222.1 - 0.029 14.5 1.2 0.082 13.1 0.8 1.8 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 DUF1942 PF09167.6 KEG06222.1 - 0.041 13.6 1.5 0.11 12.2 1.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1942) AAA_23 PF13476.1 KEG06222.1 - 0.079 13.2 1.0 0.13 12.5 0.7 1.3 1 0 0 1 1 1 0 AAA domain DUF947 PF06102.7 KEG06222.1 - 0.12 12.1 7.8 0.21 11.3 5.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF947) Arch_ATPase PF01637.13 KEG06222.1 - 0.18 11.4 2.2 0.3 10.7 1.5 1.3 1 0 0 1 1 1 0 Archaeal ATPase DUF2228 PF10228.4 KEG06222.1 - 0.31 10.5 2.7 0.55 9.7 1.9 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) Uds1 PF15456.1 KEG06222.1 - 0.48 10.4 8.2 0.19 11.7 3.5 1.9 1 1 1 2 2 2 0 Up-regulated During Septation V_ATPase_I PF01496.14 KEG06222.1 - 0.65 7.7 2.6 0.84 7.4 1.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2203 PF09969.4 KEG06222.1 - 4.2 7.6 7.8 2.4 8.4 3.4 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) PRP38 PF03371.10 KEG06223.1 - 0.00019 21.0 0.0 0.00034 20.2 0.0 1.3 1 0 0 1 1 1 1 PRP38 family Gly-zipper_OmpA PF13436.1 KEG06223.1 - 0.15 11.7 9.7 0.23 11.1 1.1 3.4 3 0 0 3 3 3 0 Glycine-zipper containing OmpA-like membrane domain DUF788 PF05620.6 KEG06223.1 - 0.82 9.5 3.7 27 4.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF788) PPP4R2 PF09184.6 KEG06224.1 - 0.0015 18.1 0.0 0.0026 17.3 0.0 1.4 2 0 0 2 2 2 1 PPP4R2 SSP160 PF06933.6 KEG06224.1 - 0.063 11.2 0.6 0.088 10.7 0.4 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Peripla_BP_6 PF13458.1 KEG06225.1 - 5.4e-09 35.8 0.0 1.1e-08 34.8 0.0 1.5 1 1 1 2 2 2 1 Periplasmic binding protein YopH_N PF09013.5 KEG06227.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 YopH, N-terminal DUF3560 PF12083.3 KEG06229.1 - 0.29 11.2 8.3 0.61 10.1 5.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) DUF3359 PF11839.3 KEG06229.1 - 2.8 8.3 14.1 0.075 13.3 4.9 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3359) DEAD_assoc PF08494.6 KEG06231.1 - 0.18 11.5 7.6 0.89 9.2 0.2 2.4 2 1 0 2 2 2 0 DEAD/H associated APC_CDC26 PF10471.4 KEG06231.1 - 0.93 10.2 9.7 0.44 11.3 4.4 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Syntaxin-6_N PF09177.6 KEG06231.1 - 1.6 9.1 10.0 1.6 9.1 1.8 3.3 2 1 1 3 3 3 0 Syntaxin 6, N-terminal RNase_H PF00075.19 KEG06232.1 - 4.1e-09 36.8 0.0 6.1e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 RNase H Drf_DAD PF06345.6 KEG06232.1 - 0.97 9.3 3.6 5.9 6.8 0.7 2.9 2 0 0 2 2 2 0 DRF Autoregulatory Domain DUF3584 PF12128.3 KEG06234.1 - 0.079 10.2 17.6 0.092 10.0 12.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3552 PF12072.3 KEG06234.1 - 0.18 11.0 27.5 0.25 10.5 11.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) V-SNARE_C PF12352.3 KEG06234.1 - 0.23 11.5 6.6 0.85 9.7 1.1 2.7 2 2 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus ScpA_ScpB PF02616.9 KEG06234.1 - 0.27 10.8 9.4 0.31 10.5 6.5 1.1 1 0 0 1 1 1 0 ScpA/B protein Jnk-SapK_ap_N PF09744.4 KEG06234.1 - 0.39 10.6 15.6 0.49 10.3 10.8 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 PLRV_ORF5 PF01690.12 KEG06234.1 - 0.8 8.7 5.8 0.92 8.5 4.0 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein LMBR1 PF04791.11 KEG06234.1 - 0.87 8.0 7.4 0.91 8.0 5.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2968 PF11180.3 KEG06234.1 - 2.7 7.3 17.5 3.4 7.0 12.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) V_ATPase_I PF01496.14 KEG06234.1 - 3.6 5.3 10.5 4.2 5.1 7.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.10 KEG06234.1 - 4.9 6.2 10.3 6.3 5.8 7.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit OEP PF02321.13 KEG06234.1 - 5.6 6.5 15.9 6.6 6.2 11.1 1.2 1 0 0 1 1 1 0 Outer membrane efflux protein Fib_alpha PF08702.5 KEG06234.1 - 6.4 6.9 8.0 8.1 6.5 5.5 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF3416 PF11896.3 KEG06234.1 - 7.6 6.4 11.4 7.6 6.4 7.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3416) HSP70 PF00012.15 KEG06234.1 - 8.5 4.1 11.2 10 3.8 7.8 1.1 1 0 0 1 1 1 0 Hsp70 protein Nbl1_Borealin_N PF10444.4 KEG06238.1 - 0.0069 15.7 1.2 1.1 8.6 0.1 3.3 3 0 0 3 3 3 1 Nbl1 / Borealin N terminal F-actin_cap_A PF01267.12 KEG06238.1 - 0.023 13.7 0.9 0.032 13.2 0.6 1.2 1 0 0 1 1 1 0 F-actin capping protein alpha subunit HalX PF08663.5 KEG06238.1 - 0.055 13.4 1.4 0.15 12.1 0.2 2.2 3 0 0 3 3 3 0 HalX domain DUF4407 PF14362.1 KEG06238.1 - 6.5 5.6 11.8 4.1 6.2 2.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Myotub-related PF06602.9 KEG06239.1 - 5.8e-81 271.9 0.0 7.6e-81 271.6 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain FYVE_2 PF02318.11 KEG06239.1 - 0.0029 17.4 2.4 0.0067 16.3 1.7 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger Y_phosphatase3 PF13350.1 KEG06239.1 - 0.0071 16.6 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family FYVE PF01363.16 KEG06239.1 - 0.01 15.7 13.1 0.11 12.4 9.1 2.6 1 1 0 1 1 1 0 FYVE zinc finger DSPc PF00782.15 KEG06239.1 - 0.016 14.8 0.1 0.029 13.9 0.1 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KEG06239.1 - 0.022 14.1 0.0 0.036 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase NIF PF03031.13 KEG06241.1 - 9.4e-30 103.3 0.0 1.7e-29 102.5 0.0 1.4 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Acid_phosphat_B PF03767.9 KEG06241.1 - 0.038 13.3 0.0 0.069 12.4 0.0 1.3 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) HAD_2 PF13419.1 KEG06241.1 - 0.07 13.3 0.4 8 6.6 0.0 3.0 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase Cmc1 PF08583.5 KEG06243.1 - 4.6e-06 26.2 5.6 0.00023 20.8 1.0 2.0 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 KEG06243.1 - 0.0019 18.0 0.8 1.2 9.1 0.0 2.2 2 0 0 2 2 2 2 CHCH domain GCK PF07802.6 KEG06243.1 - 0.021 14.9 1.0 0.029 14.4 0.7 1.2 1 0 0 1 1 1 0 GCK domain UCR_hinge PF02320.11 KEG06243.1 - 0.071 13.0 1.4 0.096 12.6 1.0 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein Pet191_N PF10203.4 KEG06243.1 - 0.24 11.4 2.3 1.2 9.2 0.1 2.2 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Gamma-thionin PF00304.15 KEG06243.1 - 0.81 9.7 5.2 2.9 7.9 0.5 2.2 1 1 1 2 2 2 0 Gamma-thionin family DAP10 PF07213.6 KEG06245.1 - 0.057 13.1 0.0 0.074 12.8 0.0 1.2 1 0 0 1 1 1 0 DAP10 membrane protein Vesiculo_matrix PF06326.7 KEG06246.1 - 0.15 11.4 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Vesiculovirus matrix protein Pkinase PF00069.20 KEG06247.1 - 2.9e-58 197.0 0.0 4e-58 196.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG06247.1 - 4.6e-32 111.1 0.0 6.5e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG06247.1 - 2.2e-05 23.6 0.0 8e-05 21.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 KEG06247.1 - 0.0028 17.0 0.2 0.044 13.1 0.1 2.3 1 1 0 1 1 1 1 RIO1 family Pox_ser-thr_kin PF05445.6 KEG06247.1 - 0.0055 15.5 0.0 0.0075 15.1 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase CBFD_NFYB_HMF PF00808.18 KEG06247.1 - 0.011 15.7 0.0 0.035 14.1 0.0 1.8 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone GAS PF13851.1 KEG06247.1 - 0.17 11.0 3.7 0.28 10.3 2.6 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding APH PF01636.18 KEG06247.1 - 2.4 7.8 8.6 4.7 6.8 3.5 3.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family Ribosomal_L12 PF00542.14 KEG06248.1 - 1.6e-18 66.4 1.2 7.4e-18 64.3 0.9 1.9 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Integrase_Zn PF02022.14 KEG06248.1 - 0.11 11.9 0.1 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Integrase Zinc binding domain Peripla_BP_6 PF13458.1 KEG06250.1 - 3.4e-09 36.5 3.7 1e-08 34.9 0.8 2.3 2 0 0 2 2 2 1 Periplasmic binding protein MtrF PF09472.5 KEG06250.1 - 0.0069 15.6 1.5 0.014 14.6 1.0 1.5 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) CobT PF06213.7 KEG06252.1 - 4.6 6.2 25.3 8.6 5.3 17.5 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Zip PF02535.17 KEG06253.1 - 4.8e-34 117.8 11.1 5.8e-34 117.5 7.7 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Malic_M PF03949.10 KEG06255.1 - 8.8e-77 258.1 0.2 1.1e-76 257.7 0.2 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KEG06255.1 - 7e-55 185.4 0.0 1.7e-54 184.1 0.0 1.7 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain zf-DHHC PF01529.15 KEG06258.1 - 2.6 7.4 6.9 0.11 11.8 0.5 2.0 2 0 0 2 2 2 0 DHHC palmitoyltransferase Cellulose_synt PF03552.9 KEG06258.1 - 9.5 4.3 7.5 13 3.9 5.2 1.1 1 0 0 1 1 1 0 Cellulose synthase Hexapep PF00132.19 KEG06259.1 - 1.3e-16 59.2 10.0 1.2e-06 27.6 0.1 3.5 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KEG06259.1 - 0.0029 17.1 10.7 0.038 13.5 1.8 2.8 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase DUF2205 PF10224.4 KEG06260.1 - 0.016 14.7 2.0 0.016 14.7 1.4 2.8 2 1 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF4228 PF14009.1 KEG06260.1 - 0.62 10.1 8.5 0.25 11.4 2.5 2.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4228) TEX13 PF15186.1 KEG06260.1 - 1.9 8.0 9.5 3.8 7.0 6.6 1.5 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family Nol1_Nop2_Fmu PF01189.12 KEG06262.1 - 2.6e-25 89.3 0.0 1e-24 87.4 0.0 1.9 2 0 0 2 2 2 1 NOL1/NOP2/sun family FtsJ PF01728.14 KEG06262.1 - 0.027 14.4 0.0 0.097 12.6 0.0 1.8 1 1 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 KEG06262.1 - 0.035 14.1 0.4 0.11 12.5 0.3 1.9 1 0 0 1 1 1 0 Methyltransferase domain NOD PF06816.8 KEG06262.1 - 2.2 7.4 5.2 0.57 9.3 0.4 2.2 2 0 0 2 2 2 0 NOTCH protein Mem_trans PF03547.13 KEG06263.1 - 4.1e-17 61.5 16.1 1.9e-15 56.1 11.1 2.7 1 1 0 1 1 1 1 Membrane transport protein Methyltransf_18 PF12847.2 KEG06264.1 - 8.8e-05 23.0 0.0 0.00016 22.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEG06264.1 - 0.001 18.7 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEG06264.1 - 0.0073 16.6 0.0 0.016 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEG06264.1 - 0.026 14.9 0.0 0.051 14.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 KEG06264.1 - 0.03 14.7 0.0 0.094 13.2 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 KEG06264.1 - 0.033 14.2 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.13 KEG06264.1 - 0.11 11.7 0.0 0.23 10.7 0.0 1.5 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain Spermine_synth PF01564.12 KEG06264.1 - 0.14 11.0 0.0 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 Spermine/spermidine synthase CoA_trans PF01144.18 KEG06265.1 - 6.4e-98 326.2 5.1 2.7e-61 206.4 0.2 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 KEG06265.1 - 0.00049 19.7 0.2 0.0009 18.9 0.1 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain DnaJ PF00226.26 KEG06268.1 - 3.9e-08 32.9 0.0 8.5e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain TFIIA PF03153.8 KEG06268.1 - 0.00034 20.6 9.4 0.0004 20.4 6.5 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.7 KEG06268.1 - 0.0025 17.5 15.3 0.0033 17.1 10.6 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein FLO_LFY PF01698.11 KEG06268.1 - 0.014 14.2 10.1 0.017 13.9 7.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Nucleoplasmin PF03066.10 KEG06268.1 - 0.035 13.6 10.4 0.052 13.0 7.2 1.3 1 0 0 1 1 1 0 Nucleoplasmin Astro_capsid PF03115.9 KEG06268.1 - 0.14 10.4 3.2 0.14 10.4 2.2 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor RXT2_N PF08595.6 KEG06268.1 - 0.15 11.8 7.7 0.23 11.2 5.4 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal SDA1 PF05285.7 KEG06268.1 - 0.15 11.2 18.4 0.21 10.8 12.7 1.1 1 0 0 1 1 1 0 SDA1 Na_trans_assoc PF06512.8 KEG06268.1 - 0.17 11.8 7.5 0.22 11.4 5.2 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated Daxx PF03344.10 KEG06268.1 - 2.2 6.6 17.0 2.8 6.3 11.8 1.2 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 KEG06268.1 - 2.4 6.1 9.2 2.9 5.8 6.4 1.3 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.10 KEG06268.1 - 6.2 5.3 8.1 7.3 5.0 5.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Pkinase PF00069.20 KEG06269.1 - 5.5e-49 166.6 0.0 7.8e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG06269.1 - 1.2e-28 99.9 0.0 1.8e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FYVE PF01363.16 KEG06269.1 - 5.5e-12 45.4 7.1 1.5e-11 44.0 5.0 1.7 1 0 0 1 1 1 1 FYVE zinc finger Kinase-like PF14531.1 KEG06269.1 - 0.00045 19.2 0.0 0.014 14.4 0.0 2.3 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 KEG06269.1 - 0.0023 17.7 0.0 0.0069 16.1 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KEG06269.1 - 0.0024 17.2 0.0 0.0036 16.6 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pox_ser-thr_kin PF05445.6 KEG06269.1 - 0.056 12.2 0.0 0.083 11.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TTL PF03133.10 KEG06270.1 - 9.1e-83 277.5 0.0 1.5e-82 276.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATP-grasp_4 PF13535.1 KEG06270.1 - 4.2e-05 23.3 0.0 9e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_YheCD PF14398.1 KEG06270.1 - 0.002 16.9 0.0 0.18 10.5 0.0 2.3 2 0 0 2 2 2 2 YheC/D like ATP-grasp RimK PF08443.6 KEG06270.1 - 0.0046 16.4 0.0 0.84 9.0 0.0 2.4 3 0 0 3 3 3 2 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.1 KEG06270.1 - 0.024 13.7 0.0 4.5 6.2 0.0 2.2 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp RHSP PF07999.6 KEG06272.1 - 1.3e-29 103.1 0.0 1.4e-29 103.0 0.0 1.0 1 0 0 1 1 1 1 Retrotransposon hot spot protein DNA_pack_C PF02499.10 KEG06272.1 - 0.052 12.2 0.2 0.06 12.0 0.1 1.1 1 0 0 1 1 1 0 Probable DNA packing protein, C-terminus HTH_17 PF12728.2 KEG06272.1 - 0.13 12.5 0.7 0.2 11.9 0.5 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF302 PF03625.9 KEG06272.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF302 AAA_10 PF12846.2 KEG06272.1 - 0.14 11.5 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain RHSP PF07999.6 KEG06273.1 - 9.2e-33 113.4 0.0 1.2e-32 113.0 0.0 1.2 1 0 0 1 1 1 1 Retrotransposon hot spot protein ERF PF04404.7 KEG06273.1 - 8.3 5.9 7.8 8.2 5.9 0.0 2.4 2 0 0 2 2 2 0 ERF superfamily CAF1 PF04857.15 KEG06276.1 - 6.9e-62 209.1 0.1 1e-61 208.5 0.0 1.3 1 1 0 1 1 1 1 CAF1 family ribonuclease FtsJ PF01728.14 KEG06279.1 - 1.9e-63 213.7 0.0 2.4e-63 213.3 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase UQ_con PF00179.21 KEG06280.1 - 2.7e-42 143.5 0.0 1.4e-40 137.9 0.0 2.5 2 1 1 3 3 3 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KEG06280.1 - 0.011 15.4 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B DLIC PF05783.6 KEG06280.1 - 4 5.9 9.1 5.6 5.5 6.3 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Menin PF05053.8 KEG06280.1 - 5.4 5.0 6.5 6.7 4.7 4.5 1.1 1 0 0 1 1 1 0 Menin MOZ_SAS PF01853.13 KEG06283.1 - 3.2e-39 134.1 0.0 4.1e-39 133.7 0.0 1.1 1 0 0 1 1 1 1 MOZ/SAS family PSP1 PF04468.7 KEG06285.1 - 2.8e-29 100.9 0.3 4.2e-29 100.3 0.2 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region dCMP_cyt_deam_2 PF08211.6 KEG06285.1 - 0.093 12.7 0.0 0.41 10.6 0.0 1.9 2 0 0 2 2 2 0 Cytidine and deoxycytidylate deaminase zinc-binding region adh_short PF00106.20 KEG06287.1 - 3.5e-21 75.8 1.4 8.9e-21 74.5 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEG06287.1 - 3.8e-11 43.2 0.2 5.2e-11 42.7 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEG06287.1 - 5e-07 29.5 1.4 5.6e-07 29.3 0.1 1.7 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 KEG06287.1 - 9.9e-05 22.4 0.4 0.0006 19.8 0.1 2.3 2 1 1 3 3 3 1 NADH(P)-binding HEM4 PF02602.10 KEG06287.1 - 0.0011 18.3 0.4 0.0061 15.8 0.0 2.2 2 1 0 2 2 2 1 Uroporphyrinogen-III synthase HemD NAD_binding_2 PF03446.10 KEG06287.1 - 0.0034 17.2 0.1 0.02 14.7 0.0 2.2 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase DEDD_Tnp_IS110 PF01548.12 KEG06287.1 - 0.039 13.6 0.0 14 5.3 0.0 2.9 3 0 0 3 3 3 0 Transposase DAO PF01266.19 KEG06287.1 - 0.065 12.1 0.1 4 6.2 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF4239 PF14023.1 KEG06289.1 - 2.6 7.3 7.0 3 7.1 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) DUF2313 PF10076.4 KEG06289.1 - 3.8 6.8 7.4 1.2 8.4 3.2 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2313) VSP PF03302.8 KEG06301.1 - 0.027 13.1 0.2 0.051 12.1 0.1 1.4 1 0 0 1 1 1 0 Giardia variant-specific surface protein Shisa PF13908.1 KEG06301.1 - 0.038 14.1 0.3 0.074 13.2 0.2 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Rifin_STEVOR PF02009.11 KEG06301.1 - 0.087 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family IncA PF04156.9 KEG06301.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 IncA protein Peripla_BP_6 PF13458.1 KEG06302.1 - 4.1e-13 49.4 0.8 1.1e-12 48.0 0.6 1.6 2 0 0 2 2 2 1 Periplasmic binding protein DHHA2 PF02833.9 KEG06302.1 - 0.1 12.8 0.6 0.97 9.6 0.0 2.3 2 0 0 2 2 2 0 DHHA2 domain Shisa PF13908.1 KEG06303.1 - 0.049 13.8 0.4 0.073 13.2 0.2 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator S1-P1_nuclease PF02265.11 KEG06304.1 - 3.3e-51 174.3 0.0 3.9e-51 174.1 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease GPI PF06560.6 KEG06304.1 - 0.059 12.3 0.6 0.097 11.6 0.4 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) NNMT_PNMT_TEMT PF01234.12 KEG06304.1 - 0.079 11.9 0.2 0.14 11.1 0.1 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family IF4E PF01652.13 KEG06305.1 - 5.4e-31 107.3 0.0 7e-31 106.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Spc42p PF11544.3 KEG06305.1 - 1.5 8.7 3.8 0.44 10.4 0.1 1.9 2 0 0 2 2 2 0 Spindle pole body component Spc42p PPR_3 PF13812.1 KEG06309.1 - 3.3e-08 33.1 0.7 0.0014 18.7 0.0 4.3 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 KEG06309.1 - 2.8e-07 30.3 0.0 0.031 14.2 0.0 3.9 2 2 3 5 5 5 3 PPR repeat family PPR PF01535.15 KEG06309.1 - 3.2e-05 23.6 0.1 13 5.9 0.0 4.9 5 0 0 5 5 5 2 PPR repeat TEX13 PF15186.1 KEG06312.1 - 0.021 14.4 1.2 0.024 14.2 0.8 1.1 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family TetR_C_2 PF08361.6 KEG06312.1 - 0.045 13.6 0.1 0.052 13.4 0.1 1.1 1 0 0 1 1 1 0 MAATS-type transcriptional repressor, C-terminal region DUF1409 PF07197.7 KEG06312.1 - 0.14 12.2 1.7 0.73 9.9 0.3 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1409) Peptidase_M8 PF01457.11 KEG06314.1 - 1e-53 182.4 5.2 1.2e-53 182.2 3.6 1.0 1 0 0 1 1 1 1 Leishmanolysin Prefoldin PF02996.12 KEG06317.1 - 7.3e-20 70.8 0.2 9.9e-20 70.3 0.1 1.3 1 0 0 1 1 1 1 Prefoldin subunit RIP PF00161.14 KEG06317.1 - 0.0042 16.3 0.7 0.081 12.0 0.0 2.0 2 0 0 2 2 2 1 Ribosome inactivating protein GAS PF13851.1 KEG06317.1 - 0.0065 15.6 1.8 0.21 10.7 0.3 2.0 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding Prefoldin_2 PF01920.15 KEG06317.1 - 0.011 15.5 0.3 0.05 13.3 0.2 2.0 2 1 0 2 2 2 0 Prefoldin subunit FUSC PF04632.7 KEG06317.1 - 0.2 10.0 5.8 0.34 9.2 4.0 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family Exo_endo_phos_2 PF14529.1 KEG06318.1 - 0.036 13.6 0.0 0.051 13.2 0.0 1.2 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase GST_N PF02798.15 KEG06319.1 - 5.4e-10 39.2 0.0 1.2e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KEG06319.1 - 3.4e-09 36.8 0.1 1.9e-08 34.4 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KEG06319.1 - 3.4e-05 23.7 0.0 8.6e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KEG06319.1 - 7.2e-05 22.6 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KEG06319.1 - 0.0073 16.7 0.0 0.056 13.9 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KEG06319.1 - 0.06 13.2 1.1 0.35 10.8 0.8 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain NOT2_3_5 PF04153.13 KEG06320.1 - 1.3e-22 80.1 0.4 1.3e-22 80.1 0.3 2.3 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family PAT1 PF09770.4 KEG06320.1 - 0.13 10.5 21.6 0.16 10.1 15.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 KEG06320.1 - 0.85 9.4 16.1 0.023 14.6 6.7 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 KEG06320.1 - 1.8 7.8 15.4 1.5 8.1 8.8 1.9 2 0 0 2 2 2 0 Vta1 like Pex14_N PF04695.8 KEG06320.1 - 9 6.3 12.9 0.55 10.2 4.5 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PRKCSH-like PF12999.2 KEG06321.1 - 1.2e-40 138.9 5.1 1.2e-40 138.9 3.5 2.7 2 1 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 KEG06321.1 - 2.4e-23 82.3 0.7 8e-23 80.6 0.5 2.0 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 KEG06321.1 - 1.6e-07 32.0 2.0 1.6e-07 32.0 1.4 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein AKNA PF12443.3 KEG06321.1 - 0.0062 16.5 0.1 0.019 14.9 0.0 1.8 1 0 0 1 1 1 1 AT-hook-containing transcription factor Ldl_recept_a PF00057.13 KEG06321.1 - 0.027 14.3 4.0 0.027 14.3 2.8 3.6 3 0 0 3 3 3 0 Low-density lipoprotein receptor domain class A Mnd1 PF03962.10 KEG06321.1 - 0.049 13.2 12.8 1.1 8.9 0.1 2.2 2 0 0 2 2 2 0 Mnd1 family ParB PF08775.5 KEG06321.1 - 0.064 13.5 4.2 3.2 8.0 1.2 2.3 2 0 0 2 2 2 0 ParB family Occludin_ELL PF07303.8 KEG06321.1 - 0.52 11.0 4.5 3.3 8.4 0.1 2.4 2 0 0 2 2 2 0 Occludin homology domain AAA_27 PF13514.1 KEG06321.1 - 1.5 6.3 13.1 1.7 6.2 5.4 2.0 2 0 0 2 2 2 0 AAA domain Nup88 PF10168.4 KEG06321.1 - 2 6.1 8.9 1.1 6.9 0.1 2.1 2 0 0 2 2 2 0 Nuclear pore component Phage_GP20 PF06810.6 KEG06321.1 - 2.2 7.6 11.0 6.8 6.1 4.1 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 Vinculin PF01044.14 KEG06322.1 - 0.083 10.8 0.0 0.1 10.5 0.0 1.1 1 0 0 1 1 1 0 Vinculin family DUF4506 PF14958.1 KEG06323.1 - 0.018 14.5 0.0 0.055 13.0 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4506) MRP-L46 PF11788.3 KEG06324.1 - 9.7e-11 42.3 0.1 2.2e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 Rotamase_3 PF13616.1 KEG06325.1 - 0.0012 19.0 0.1 11 6.3 0.0 3.5 2 1 2 4 4 4 2 PPIC-type PPIASE domain PA28_alpha PF02251.13 KEG06325.1 - 0.033 14.3 0.0 41 4.4 0.0 3.7 4 0 0 4 4 4 0 Proteasome activator pa28 alpha subunit Phage_DsbA PF11126.3 KEG06325.1 - 0.28 11.3 1.1 75 3.5 0.0 3.2 3 0 0 3 3 3 0 Transcriptional regulator DsbA Acyl-CoA_dh_C PF12806.2 KEG06326.1 - 3.1e-22 78.8 0.0 1e-21 77.1 0.0 1.8 2 0 0 2 2 2 1 Acetyl-CoA dehydrogenase C-terminal like Acyl-CoA_dh_1 PF00441.19 KEG06326.1 - 1.7e-19 70.4 1.7 1.1e-18 67.7 0.7 2.4 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KEG06326.1 - 8.8e-15 55.2 0.0 2.1e-14 54.0 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KEG06326.1 - 5.8e-14 51.3 0.0 1.2e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KEG06326.1 - 5.1e-06 26.7 0.0 1e-05 25.7 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AcylCoA_DH_N PF12418.3 KEG06326.1 - 0.0053 16.4 0.1 0.012 15.2 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase N terminal Mucin PF01456.12 KEG06328.1 - 0.032 13.9 31.1 0.063 13.0 4.1 3.8 1 1 1 2 2 2 0 Mucin-like glycoprotein PsaD PF02531.11 KEG06328.1 - 0.08 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 PsaD DM13 PF10517.4 KEG06329.1 - 0.088 13.2 0.1 0.4 11.0 0.0 2.1 2 0 0 2 2 2 0 Electron transfer DM13 LSM PF01423.17 KEG06330.1 - 2.7e-10 39.6 0.1 3.2e-10 39.4 0.1 1.2 1 0 0 1 1 1 1 LSM domain DUF413 PF04219.7 KEG06333.1 - 0.18 11.5 7.8 0.31 10.8 0.4 2.5 2 1 0 2 2 2 0 Protein of unknown function, DUF DUF3708 PF12501.3 KEG06333.1 - 0.51 10.1 5.9 0.051 13.4 1.1 1.5 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter RAMP4 PF06624.7 KEG06333.1 - 3 7.4 4.2 13 5.3 0.5 2.4 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 DinB PF05163.7 KEG06334.1 - 0.081 12.6 0.1 0.11 12.1 0.1 1.2 1 1 0 1 1 1 0 DinB family Ras PF00071.17 KEG06336.1 - 1.3e-63 213.2 0.3 1.5e-63 213.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEG06336.1 - 4.8e-21 75.4 0.0 6.6e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEG06336.1 - 8.1e-16 57.7 0.1 9e-16 57.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KEG06336.1 - 2.8e-06 26.6 0.1 3.4e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KEG06336.1 - 5.9e-05 22.3 0.1 7.4e-05 22.0 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KEG06336.1 - 0.00011 22.1 0.1 0.00018 21.4 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KEG06336.1 - 0.00018 20.9 0.2 0.0004 19.8 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KEG06336.1 - 0.0016 17.7 0.0 0.008 15.4 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA PF00004.24 KEG06336.1 - 0.0052 16.9 0.0 0.35 11.0 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEG06336.1 - 0.0058 16.7 0.0 0.01 15.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KEG06336.1 - 0.015 14.5 0.0 0.037 13.2 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 KEG06336.1 - 0.025 14.1 0.2 0.059 12.9 0.0 1.6 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.1 KEG06336.1 - 0.034 13.6 0.0 0.099 12.1 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 KEG06336.1 - 0.034 14.1 0.1 0.064 13.2 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 KEG06336.1 - 0.058 13.6 0.1 0.16 12.2 0.1 1.8 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.9 KEG06336.1 - 0.15 11.8 0.0 0.35 10.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) G-alpha PF00503.15 KEG06336.1 - 0.38 9.4 5.1 4.4 5.8 0.8 2.7 1 1 1 2 2 2 0 G-protein alpha subunit V-SNARE_C PF12352.3 KEG06337.1 - 5.7e-06 26.3 1.6 1e-05 25.4 1.1 1.4 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus DUF3609 PF12259.3 KEG06337.1 - 0.16 10.6 0.0 0.19 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) Ribosomal_S4 PF00163.14 KEG06338.1 - 1e-27 96.3 0.5 2e-27 95.3 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 KEG06338.1 - 1.6e-12 46.6 0.3 3.2e-12 45.6 0.2 1.6 1 0 0 1 1 1 1 S4 domain FAD-oxidase_C PF02913.14 KEG06340.1 - 1.6e-43 148.8 0.0 2.3e-43 148.3 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KEG06340.1 - 5.8e-34 116.5 0.5 1.1e-33 115.6 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain Peripla_BP_6 PF13458.1 KEG06344.1 - 6.9e-14 51.9 2.7 1e-13 51.4 1.9 1.2 1 0 0 1 1 1 1 Periplasmic binding protein Nup88 PF10168.4 KEG06346.1 - 0.032 12.1 2.2 0.053 11.3 1.5 1.3 1 0 0 1 1 1 0 Nuclear pore component Laminin_II PF06009.7 KEG06346.1 - 1.5 8.5 20.0 3.4 7.4 4.2 3.3 2 1 1 3 3 3 0 Laminin Domain II IncA PF04156.9 KEG06346.1 - 3.1 7.3 11.8 0.17 11.4 2.0 3.0 2 2 1 3 3 3 0 IncA protein LST1 PF05083.8 KEG06346.1 - 4.4 7.3 6.1 14 5.7 1.2 2.8 2 1 0 2 2 2 0 LST-1 protein Lipase_GDSL_3 PF14606.1 KEG06346.1 - 5 6.8 6.4 17 5.0 0.1 2.7 1 1 2 3 3 3 0 GDSL-like Lipase/Acylhydrolase family Myosin_tail_1 PF01576.14 KEG06346.1 - 6.4 4.3 21.7 0.76 7.4 5.8 2.2 2 0 0 2 2 2 0 Myosin tail MIF4G PF02854.14 KEG06347.1 - 3e-16 59.4 1.5 4.1e-15 55.7 0.4 2.3 2 0 0 2 2 2 1 MIF4G domain V-SNARE PF05008.10 KEG06347.1 - 0.019 15.1 0.5 0.062 13.4 0.3 1.9 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus Innate_immun PF12782.2 KEG06347.1 - 0.051 12.7 16.5 0.089 12.0 11.5 1.3 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Macoilin PF09726.4 KEG06347.1 - 0.91 7.7 3.6 1.6 6.9 2.5 1.3 1 0 0 1 1 1 0 Transmembrane protein Zip PF02535.17 KEG06347.1 - 1.2 8.0 11.2 2.2 7.2 7.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter CDK2AP PF09806.4 KEG06347.1 - 5.6 7.1 6.0 11 6.1 4.2 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DSPc PF00782.15 KEG06352.1 - 8.5e-32 109.5 0.0 1.3e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KEG06352.1 - 0.0013 18.1 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Thioredoxin PF00085.15 KEG06353.1 - 1.1e-08 34.7 0.0 1.9e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.11 KEG06353.1 - 2.3e-06 26.5 0.2 3.4e-06 26.0 0.2 1.2 1 0 0 1 1 1 1 Phosducin VKOR PF07884.9 KEG06354.1 - 1e-10 41.6 17.4 5.4e-10 39.2 12.1 1.8 1 1 0 1 1 1 1 Vitamin K epoxide reductase family Cyclin PF08613.6 KEG06355.1 - 3.7e-21 76.1 0.1 6.1e-21 75.3 0.1 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KEG06355.1 - 7.2e-06 25.5 0.1 1.6e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Mgr1 PF08602.5 KEG06357.1 - 0.17 10.8 3.4 0.32 9.9 2.3 1.5 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit YebO PF13974.1 KEG06357.1 - 0.43 10.4 3.1 2 8.2 2.1 2.2 1 0 0 1 1 1 0 YebO-like protein V_ATPase_I PF01496.14 KEG06357.1 - 1 7.1 14.3 0.034 12.0 5.7 1.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Mucin PF01456.12 KEG06358.1 - 0.0032 17.2 9.5 0.0032 17.2 6.6 3.0 3 1 0 3 3 3 2 Mucin-like glycoprotein Ferritin PF00210.19 KEG06358.1 - 0.024 14.3 0.3 0.024 14.3 0.2 3.2 1 1 1 3 3 3 0 Ferritin-like domain Sulphotransf PF09037.5 KEG06358.1 - 0.066 12.6 0.1 0.14 11.6 0.1 1.5 1 1 0 1 1 1 0 Stf0 sulphotransferase Costars PF14705.1 KEG06360.1 - 0.00029 20.7 0.0 0.00043 20.2 0.0 1.3 1 0 0 1 1 1 1 Costars AMP-binding PF00501.23 KEG06361.1 - 1.6e-82 277.1 0.0 2.2e-82 276.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme BT1 PF03092.11 KEG06362.1 - 1e-46 159.5 1.0 1.2e-46 159.3 0.7 1.0 1 0 0 1 1 1 1 BT1 family MFS_1 PF07690.11 KEG06362.1 - 0.034 12.8 0.6 0.063 11.9 0.5 1.3 1 1 0 1 1 1 0 Major Facilitator Superfamily 7TM_GPCR_Srh PF10318.4 KEG06362.1 - 0.081 11.7 0.2 0.14 10.9 0.1 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh MpPF26 PF07666.6 KEG06362.1 - 0.2 11.5 0.9 0.73 9.7 0.2 1.9 2 0 0 2 2 2 0 M penetrans paralogue family 26 ABC2_membrane_3 PF12698.2 KEG06363.1 - 5.8e-20 71.6 22.7 1.6e-19 70.1 13.5 2.1 2 0 0 2 2 2 2 ABC-2 family transporter protein K_channel_TID PF07941.6 KEG06365.1 - 0.045 13.9 1.5 0.053 13.7 0.2 1.7 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Aa_trans PF01490.13 KEG06370.1 - 2e-46 158.3 19.5 2.3e-46 158.1 13.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KEG06370.1 - 3.3e-11 42.6 7.1 3.3e-11 42.6 4.9 2.3 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family Chromo PF00385.19 KEG06372.1 - 9.5e-06 25.1 0.0 2.7e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.1 KEG06372.1 - 0.0064 16.3 0.2 0.014 15.2 0.2 1.6 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 UAA PF08449.6 KEG06374.1 - 5.6e-13 48.4 6.1 1.2e-12 47.4 4.2 1.4 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KEG06374.1 - 4.8e-07 29.8 17.6 6.5e-05 22.9 4.7 3.2 3 1 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 KEG06374.1 - 1e-06 28.0 1.9 1.9e-06 27.2 0.1 2.0 2 0 0 2 2 2 1 Nucleotide-sugar transporter DUF914 PF06027.7 KEG06374.1 - 1.5e-06 27.3 9.0 4.9e-06 25.6 1.4 2.3 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF914) UPF0546 PF10639.4 KEG06374.1 - 0.00034 20.4 0.8 0.00034 20.4 0.5 1.9 2 0 0 2 2 2 1 Uncharacterised protein family UPF0546 EmrE PF13536.1 KEG06374.1 - 0.001 19.2 7.1 0.001 19.2 4.9 3.3 3 1 1 4 4 4 2 Multidrug resistance efflux transporter TPT PF03151.11 KEG06374.1 - 0.0044 16.6 15.2 0.017 14.7 1.4 2.4 2 0 0 2 2 2 2 Triose-phosphate Transporter family HlyIII PF03006.15 KEG06374.1 - 0.31 10.4 14.9 0.02 14.3 1.7 2.8 3 0 0 3 3 3 0 Haemolysin-III related Pkinase PF00069.20 KEG06376.1 - 1.1e-62 211.5 0.0 1.6e-62 210.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG06376.1 - 6.9e-47 159.7 0.0 1.1e-46 159.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG06376.1 - 1.5e-07 30.7 0.2 2.1e-06 26.9 0.0 2.4 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 KEG06376.1 - 0.0022 17.7 1.3 2.4 7.8 0.0 2.8 3 0 0 3 3 3 2 Phosphotransferase enzyme family GFA PF04828.9 KEG06376.1 - 0.013 15.4 0.2 6.9 6.6 0.0 2.6 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-RING_2 PF13639.1 KEG06377.1 - 8.6e-10 38.2 10.5 1.6e-09 37.4 7.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KEG06377.1 - 5.4e-06 25.9 7.8 8.6e-06 25.3 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEG06377.1 - 3.1e-05 23.8 10.3 5.9e-05 23.0 7.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEG06377.1 - 0.0034 17.0 9.8 0.0059 16.3 6.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KEG06377.1 - 0.017 15.2 7.4 0.045 13.8 5.2 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger DUF1645 PF07816.6 KEG06378.1 - 0.015 15.7 1.5 0.018 15.4 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) Thioredoxin PF00085.15 KEG06380.1 - 3.2e-15 55.6 0.0 9.1e-15 54.2 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KEG06380.1 - 0.00014 22.0 0.7 0.011 15.9 0.0 3.3 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KEG06380.1 - 0.0012 18.9 0.3 0.22 11.6 0.0 3.4 3 1 1 4 4 4 1 Thioredoxin-like Thioredoxin_7 PF13899.1 KEG06380.1 - 0.027 14.5 0.0 0.084 12.9 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_6 PF13848.1 KEG06380.1 - 0.046 13.5 0.0 6.7 6.4 0.0 3.0 2 1 0 2 2 2 0 Thioredoxin-like domain Pkinase PF00069.20 KEG06383.1 - 4.4e-45 153.8 0.0 1.6e-44 152.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG06383.1 - 8.2e-25 87.3 0.0 6.1e-24 84.4 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 KEG06383.1 - 0.0027 16.7 0.0 0.0076 15.3 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Glutaredoxin PF00462.19 KEG06387.1 - 1.1e-16 60.5 0.1 1.6e-13 50.4 0.0 2.5 2 0 0 2 2 2 2 Glutaredoxin Thioredoxin PF00085.15 KEG06387.1 - 3.2e-13 49.2 0.0 8.8e-13 47.8 0.1 1.7 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 KEG06387.1 - 0.0018 18.3 0.1 0.0059 16.6 0.0 1.9 2 1 1 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.16 KEG06387.1 - 0.01 15.5 0.0 0.026 14.2 0.0 1.7 1 0 0 1 1 1 0 AhpC/TSA family DUF4319 PF14203.1 KEG06387.1 - 0.014 14.9 0.0 0.032 13.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4319) AAA PF00004.24 KEG06388.1 - 3e-37 127.7 0.0 5.3e-37 126.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KEG06388.1 - 4.6e-08 33.9 0.1 1.6e-07 32.1 0.0 2.1 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 KEG06388.1 - 2.4e-07 30.0 0.0 4.6e-07 29.1 0.0 1.4 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KEG06388.1 - 1.4e-06 28.4 0.1 4.9e-06 26.6 0.0 1.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 KEG06388.1 - 1.9e-06 27.6 0.0 1.1e-05 25.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KEG06388.1 - 3.3e-06 27.2 0.1 8.1e-05 22.7 0.1 2.5 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 KEG06388.1 - 5.3e-06 25.4 0.0 1.3e-05 24.0 0.0 1.6 1 1 1 2 2 2 1 TIP49 C-terminus AAA_14 PF13173.1 KEG06388.1 - 1.4e-05 24.9 0.0 2.6e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KEG06388.1 - 3e-05 23.9 0.0 7.3e-05 22.6 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.1 KEG06388.1 - 3.8e-05 23.9 0.0 8.1e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KEG06388.1 - 0.00011 21.6 0.0 0.00019 20.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 KEG06388.1 - 0.00012 21.2 0.0 0.00019 20.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_2 PF07724.9 KEG06388.1 - 0.00041 20.3 0.0 0.0022 17.9 0.0 2.1 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 KEG06388.1 - 0.00043 19.9 0.1 0.0014 18.2 0.0 2.0 2 0 0 2 2 1 1 Part of AAA domain RNA_helicase PF00910.17 KEG06388.1 - 0.00049 20.2 0.0 0.0018 18.4 0.0 2.0 1 0 0 1 1 1 1 RNA helicase SKI PF01202.17 KEG06388.1 - 0.0011 18.9 0.1 0.0024 17.7 0.0 1.6 2 0 0 2 2 1 1 Shikimate kinase AAA_28 PF13521.1 KEG06388.1 - 0.0018 18.2 0.0 0.0035 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KEG06388.1 - 0.0025 17.4 0.0 0.0049 16.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 KEG06388.1 - 0.0029 17.6 0.0 0.0057 16.7 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 KEG06388.1 - 0.003 16.7 0.0 0.0058 15.8 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 KEG06388.1 - 0.0045 16.6 0.0 0.0077 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KEG06388.1 - 0.0071 15.7 0.4 0.056 12.8 0.1 2.1 1 1 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.12 KEG06388.1 - 0.0078 15.1 0.0 0.045 12.6 0.0 1.9 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 NACHT PF05729.7 KEG06388.1 - 0.01 15.5 0.0 0.021 14.4 0.0 1.6 1 1 0 1 1 1 0 NACHT domain Bac_DnaA PF00308.13 KEG06388.1 - 0.019 14.6 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein UPF0079 PF02367.12 KEG06388.1 - 0.02 14.5 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Rad17 PF03215.10 KEG06388.1 - 0.021 13.5 0.0 0.037 12.7 0.0 1.4 2 0 0 2 2 1 0 Rad17 cell cycle checkpoint protein PhoH PF02562.11 KEG06388.1 - 0.024 13.8 0.0 0.039 13.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_29 PF13555.1 KEG06388.1 - 0.034 13.6 0.0 0.11 11.9 0.0 1.8 2 0 0 2 2 1 0 P-loop containing region of AAA domain DUF2075 PF09848.4 KEG06388.1 - 0.039 12.9 0.0 0.05 12.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.21 KEG06388.1 - 0.04 13.4 0.0 0.12 11.7 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.1 KEG06388.1 - 0.089 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain IPT PF01745.11 KEG06388.1 - 0.09 11.9 0.0 0.36 9.9 0.0 1.9 2 0 0 2 2 2 0 Isopentenyl transferase Arch_ATPase PF01637.13 KEG06388.1 - 0.11 12.1 0.0 1.1 8.8 0.0 1.9 1 1 1 2 2 2 0 Archaeal ATPase Cation_ATPase_C PF00689.16 KEG06389.1 - 2.4e-33 115.1 0.3 3e-33 114.8 0.2 1.1 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus PhrC_PhrF PF11131.3 KEG06389.1 - 0.01 15.3 0.3 0.024 14.1 0.2 1.6 1 0 0 1 1 1 0 Rap-phr extracellular signalling JAB PF01398.16 KEG06390.1 - 0.012 15.3 0.0 0.029 14.0 0.0 1.7 2 0 0 2 2 2 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF4250 PF14056.1 KEG06390.1 - 0.071 12.8 3.6 1.2 8.9 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) Pkinase PF00069.20 KEG06396.1 - 1.3e-59 201.4 0.0 1.8e-59 201.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG06396.1 - 7.7e-41 139.8 0.0 1e-40 139.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG06396.1 - 7.4e-09 34.9 0.0 1.6e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like PH PF00169.24 KEG06396.1 - 0.00028 21.0 0.0 0.00049 20.2 0.0 1.4 1 0 0 1 1 1 1 PH domain Pox_ser-thr_kin PF05445.6 KEG06396.1 - 0.038 12.7 0.1 0.058 12.1 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF1767 PF08585.7 KEG06396.1 - 0.13 12.5 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1767) PH_9 PF15410.1 KEG06396.1 - 0.15 12.2 0.6 0.99 9.5 0.4 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain Mucin PF01456.12 KEG06397.1 - 5.9 6.6 21.6 0.26 11.0 10.6 2.0 2 1 0 2 2 2 0 Mucin-like glycoprotein Mucin PF01456.12 KEG06399.1 - 0.00088 19.0 6.6 0.0012 18.6 4.6 1.4 1 1 0 1 1 1 1 Mucin-like glycoprotein M-factor PF03855.8 KEG06399.1 - 7.2 6.6 8.2 0.36 10.8 1.9 1.8 2 0 0 2 2 2 0 M-factor Arm PF00514.18 KEG06401.1 - 0.00037 20.2 0.1 0.46 10.3 0.0 3.1 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Glyco_hydro_98M PF08306.6 KEG06402.1 - 0.14 10.8 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 98 Peptidase_M8 PF01457.11 KEG06404.1 - 5.6e-09 34.8 0.8 5.6e-09 34.8 0.5 1.4 2 0 0 2 2 2 1 Leishmanolysin Peptidase_M8 PF01457.11 KEG06405.1 - 1.9e-18 66.1 1.3 2e-18 66.0 0.9 1.1 1 0 0 1 1 1 1 Leishmanolysin DUF641 PF04859.7 KEG06406.1 - 0.13 12.0 4.8 0.053 13.2 1.1 1.9 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) TrmB PF01978.14 KEG06407.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Sporozoite_P67 PF05642.6 KEG06410.1 - 0.58 7.9 10.7 0.077 10.8 0.9 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen BMFP PF04380.8 KEG06412.1 - 0.011 15.8 0.0 0.029 14.4 0.0 1.7 2 0 0 2 2 2 0 Membrane fusogenic activity CHCH PF06747.8 KEG06412.1 - 0.059 13.3 1.2 0.13 12.2 0.9 1.6 1 0 0 1 1 1 0 CHCH domain LRR_4 PF12799.2 KEG06413.1 - 1.4e-07 30.9 0.0 0.0002 20.8 0.0 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG06413.1 - 0.00017 21.2 0.4 0.00049 19.8 0.1 2.0 3 0 0 3 3 3 1 Leucine rich repeat LRR_9 PF14580.1 KEG06413.1 - 0.078 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.1 KEG06413.1 - 0.11 12.6 1.3 8.7 6.7 0.0 3.4 2 1 1 3 3 3 0 Leucine Rich repeat LRR_7 PF13504.1 KEG06413.1 - 0.26 11.6 1.1 63 4.4 0.0 4.1 4 0 0 4 4 4 0 Leucine rich repeat SpoIIE PF07228.7 KEG06416.1 - 4.6e-07 29.7 0.4 9.5e-06 25.4 0.3 2.6 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 KEG06416.1 - 9.9e-06 25.0 0.0 1.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 KEG06416.1 - 0.062 12.6 0.0 11 5.2 0.0 2.2 2 0 0 2 2 2 0 Protein phosphatase 2C Vhr1 PF04001.8 KEG06418.1 - 0.079 12.8 0.0 5.7 6.9 0.0 3.2 3 0 0 3 3 3 0 Transcription factor Vhr1 DnaB_2 PF07261.6 KEG06418.1 - 0.12 12.0 0.0 5.8 6.6 0.0 2.9 2 0 0 2 2 2 0 Replication initiation and membrane attachment Slu7 PF11708.3 KEG06419.1 - 0.0009 19.0 2.1 0.004 16.9 0.0 2.7 3 0 0 3 3 3 1 Pre-mRNA splicing Prp18-interacting factor Amidohydro_4 PF13147.1 KEG06420.1 - 4.5e-23 82.6 6.3 3.4e-22 79.7 4.4 2.3 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KEG06420.1 - 9.6e-17 61.6 0.1 3.7e-16 59.6 0.1 1.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KEG06420.1 - 3.3e-11 43.0 9.0 3.3e-08 33.1 1.0 3.3 1 1 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 KEG06420.1 - 3.8e-10 39.4 0.9 1.5e-09 37.4 0.1 2.3 2 1 0 2 2 2 1 Amidohydrolase ADK PF00406.17 KEG06422.1 - 9.3e-51 171.6 0.0 1.1e-50 171.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 KEG06422.1 - 2.7e-14 52.5 0.0 1.5e-13 50.1 0.0 2.1 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_17 PF13207.1 KEG06422.1 - 1.6e-08 35.3 0.0 3.2e-08 34.3 0.0 1.6 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 KEG06422.1 - 0.0021 17.9 0.0 0.0043 16.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KEG06422.1 - 0.068 13.1 0.0 0.11 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KEG06422.1 - 0.1 12.9 0.2 0.22 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain Herpes_UL52 PF03121.10 KEG06423.1 - 0.0036 16.9 2.4 0.0087 15.7 1.6 1.6 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase Mucin PF01456.12 KEG06424.1 - 5.5e-07 29.4 65.3 1.8e-05 24.5 12.6 4.2 1 1 3 4 4 4 3 Mucin-like glycoprotein Laminin_II PF06009.7 KEG06425.1 - 0.073 12.8 9.9 0.17 11.6 2.1 2.1 2 0 0 2 2 2 0 Laminin Domain II Syntaxin PF00804.20 KEG06425.1 - 0.087 12.9 3.7 0.25 11.5 2.6 1.9 1 1 0 1 1 1 0 Syntaxin AAA_13 PF13166.1 KEG06425.1 - 0.4 9.0 7.5 0.54 8.6 5.2 1.1 1 0 0 1 1 1 0 AAA domain SecD-TM1 PF13721.1 KEG06425.1 - 0.47 10.7 3.6 1.8 8.8 0.5 2.1 2 0 0 2 2 2 0 SecD export protein N-terminal TM region Mucin PF01456.12 KEG06425.1 - 0.65 9.7 9.5 1.4 8.6 6.6 1.8 1 1 0 1 1 1 0 Mucin-like glycoprotein CDC37_N PF03234.9 KEG06425.1 - 0.83 9.9 5.8 1.1 9.5 4.0 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding DUF4611 PF15387.1 KEG06425.1 - 1.8 8.7 4.9 3.6 7.8 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) DUF3450 PF11932.3 KEG06425.1 - 1.8 7.7 8.8 0.21 10.8 1.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF2277 PF10041.4 KEG06425.1 - 4.3 7.3 9.1 6.4 6.8 0.2 3.2 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2277) TPR_MLP1_2 PF07926.7 KEG06425.1 - 7 6.4 9.6 51 3.6 6.6 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein RP-C_C PF11800.3 KEG06426.1 - 0.0043 16.7 1.2 0.0084 15.8 0.8 1.4 1 0 0 1 1 1 1 Replication protein C C-terminal region Muted PF14942.1 KEG06426.1 - 0.025 14.4 1.5 0.049 13.5 1.1 1.5 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein M16C_assoc PF08367.6 KEG06426.1 - 0.05 12.4 3.4 0.089 11.6 2.4 1.4 1 0 0 1 1 1 0 Peptidase M16C associated IncA PF04156.9 KEG06426.1 - 0.096 12.2 6.1 0.15 11.6 4.2 1.2 1 0 0 1 1 1 0 IncA protein HisKA_3 PF07730.8 KEG06426.1 - 0.14 12.5 4.9 0.15 12.3 1.5 2.3 2 2 0 2 2 2 0 Histidine kinase TBPIP PF07106.8 KEG06426.1 - 0.26 10.8 5.9 0.081 12.4 2.3 1.5 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spc24 PF08286.6 KEG06426.1 - 0.3 10.7 3.2 0.57 9.9 2.2 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF1682 PF07946.9 KEG06426.1 - 0.43 9.3 4.8 0.52 9.1 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Mucin PF01456.12 KEG06426.1 - 2.3 8.0 10.2 0.48 10.1 2.2 2.7 2 1 0 2 2 2 0 Mucin-like glycoprotein PAT1 PF09770.4 KEG06429.1 - 6.5 4.8 23.7 7 4.7 16.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2935 PF11155.3 KEG06430.1 - 0.24 11.4 10.9 1.6 8.7 2.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) IncA PF04156.9 KEG06430.1 - 6.9 6.2 12.1 4.7 6.7 0.4 3.1 2 1 1 3 3 3 0 IncA protein MGC-24 PF05283.6 KEG06431.1 - 0.0018 18.1 1.8 0.0021 17.8 1.3 1.2 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24) Mucin PF01456.12 KEG06431.1 - 0.0038 17.0 3.0 0.0041 16.9 2.1 1.3 1 1 0 1 1 1 1 Mucin-like glycoprotein TerB PF05099.8 KEG06431.1 - 0.0063 16.2 5.4 0.0067 16.1 3.3 1.4 1 1 0 1 1 1 1 Tellurite resistance protein TerB DUF4094 PF13334.1 KEG06431.1 - 0.0063 16.8 0.3 0.0063 16.8 0.2 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4094) VTC PF09359.5 KEG06431.1 - 0.032 13.2 0.3 0.041 12.8 0.2 1.1 1 0 0 1 1 1 0 VTC domain Hydrolase_6 PF13344.1 KEG06432.1 - 0.19 11.6 1.7 0.49 10.3 0.0 2.5 2 2 0 2 2 2 0 Haloacid dehalogenase-like hydrolase LMBR1 PF04791.11 KEG06432.1 - 1.1 7.7 9.6 1.7 7.1 6.6 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein Kinesin PF00225.18 KEG06433.1 - 4.3e-34 117.7 0.0 5.3e-34 117.4 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Ribosomal_L22 PF00237.14 KEG06434.1 - 1.2e-30 105.5 0.1 1.4e-30 105.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF1279 PF06916.8 KEG06435.1 - 0.002 18.4 0.1 0.0032 17.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) WW PF00397.21 KEG06435.1 - 0.074 12.9 0.3 0.15 11.9 0.2 1.5 1 0 0 1 1 1 0 WW domain MVP_shoulder PF11978.3 KEG06436.1 - 2.3e-46 156.4 0.1 4.3e-46 155.6 0.0 1.5 1 0 0 1 1 1 1 Shoulder domain Vault PF01505.13 KEG06436.1 - 1.8e-44 149.4 1.6 1e-11 44.6 0.0 5.6 5 0 0 5 5 5 4 Major Vault Protein repeat WEMBL PF05701.6 KEG06438.1 - 1.1 7.5 42.2 0.22 9.9 8.5 2.1 2 0 0 2 2 2 0 Weak chloroplast movement under blue light Syntaxin-6_N PF09177.6 KEG06438.1 - 7.7 6.9 12.9 6.3 7.2 1.0 3.5 2 1 2 4 4 4 0 Syntaxin 6, N-terminal Mucin PF01456.12 KEG06440.1 - 0.00092 19.0 9.8 0.00092 19.0 6.8 2.8 2 1 0 2 2 2 1 Mucin-like glycoprotein Macoilin PF09726.4 KEG06441.1 - 3.8 5.6 8.1 5.3 5.1 5.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Pkinase PF00069.20 KEG06449.1 - 2.1e-25 89.3 0.0 2.2e-24 86.0 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG06449.1 - 9.5e-11 41.2 0.0 2.1e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase FAM86 PF14904.1 KEG06449.1 - 0.023 14.4 0.0 0.064 12.9 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function DUF2841 PF11001.3 KEG06449.1 - 0.096 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2841) ELH PF02323.10 KEG06451.1 - 0.47 9.5 6.4 0.053 12.6 1.2 1.7 2 0 0 2 2 2 0 Egg-laying hormone precursor SET PF00856.23 KEG06455.1 - 1.2e-10 41.9 0.9 1.3e-09 38.6 0.4 2.0 2 0 0 2 2 2 1 SET domain zf-CCCH PF00642.19 KEG06456.1 - 2.2e-05 24.0 0.6 3.5e-05 23.3 0.4 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KEG06456.1 - 0.19 11.7 0.9 0.32 11.0 0.6 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type RAM PF15320.1 KEG06460.1 - 0.092 13.0 13.4 0.7 10.1 0.7 2.2 2 0 0 2 2 2 0 mRNA cap methylation, RNMT-activating mini protein Corona_nucleoca PF00937.13 KEG06460.1 - 0.31 9.9 4.8 0.36 9.7 3.3 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein GRP PF07172.6 KEG06460.1 - 2.8 8.4 15.5 5.7 7.4 10.7 1.5 1 0 0 1 1 1 0 Glycine rich protein family DUF1509 PF07420.6 KEG06460.1 - 4.1 6.5 12.0 5.6 6.1 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) DAN PF03045.10 KEG06461.1 - 0.038 13.3 1.7 0.047 13.0 1.2 1.2 1 0 0 1 1 1 0 DAN domain DEAD PF00270.24 KEG06462.1 - 4e-45 153.3 0.0 2.2e-42 144.4 0.0 2.1 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KEG06462.1 - 2e-22 78.8 0.0 2.9e-21 75.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEG06462.1 - 0.0016 18.2 0.0 0.032 14.0 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 KEG06462.1 - 0.037 13.9 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain Metalloenzyme PF01676.13 KEG06462.1 - 0.063 12.6 0.0 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily CMS1 PF14617.1 KEG06462.1 - 0.079 12.0 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit PSRT PF07636.6 KEG06464.1 - 1.3 8.5 8.2 0.77 9.2 2.3 2.3 2 0 0 2 2 2 0 PSRT Sec1 PF00995.18 KEG06465.1 - 3.7e-89 299.8 0.0 4.3e-89 299.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family TPR_11 PF13414.1 KEG06472.1 - 1.2e-19 69.6 3.8 3.6e-13 48.9 0.1 2.5 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KEG06472.1 - 2e-14 52.4 8.1 2.7e-07 29.9 0.7 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEG06472.1 - 1.2e-11 43.5 7.5 4.2e-06 26.2 1.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEG06472.1 - 7.7e-07 28.9 2.9 0.0036 17.1 1.3 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEG06472.1 - 4.6e-05 23.6 0.7 0.07 13.8 0.6 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEG06472.1 - 0.00027 20.4 6.0 0.00083 18.9 0.4 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEG06472.1 - 0.00028 20.4 2.6 0.066 13.0 0.5 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEG06472.1 - 0.0017 19.0 5.4 0.0094 16.6 3.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEG06472.1 - 0.0049 17.1 2.0 0.12 12.7 1.9 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.13 KEG06472.1 - 0.0096 15.7 2.4 3.3 7.6 0.0 2.9 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 KEG06472.1 - 0.026 14.9 0.9 0.026 14.9 0.6 2.6 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 KEG06472.1 - 0.035 14.3 0.4 17 5.9 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Metallophos PF00149.23 KEG06475.1 - 6.3e-22 77.9 0.0 2.3e-21 76.1 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase FCP1_C PF09309.5 KEG06475.1 - 1.5 8.0 4.5 12 5.0 0.0 2.2 2 0 0 2 2 2 0 FCP1, C-terminal CHORD PF04968.7 KEG06478.1 - 1e-47 160.2 21.0 7.4e-24 83.7 3.1 2.2 2 0 0 2 2 2 2 CHORD Granulin PF00396.13 KEG06478.1 - 0.54 10.3 6.0 3.6 7.7 0.0 2.9 2 1 0 2 2 2 0 Granulin Ribosomal_S17 PF00366.15 KEG06479.1 - 4.9e-25 87.3 0.7 4.9e-25 87.3 0.5 1.7 2 0 0 2 2 2 1 Ribosomal protein S17 Shisa PF13908.1 KEG06480.1 - 0.011 15.8 2.2 0.022 14.9 1.5 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Tetraspannin PF00335.15 KEG06480.1 - 0.033 13.4 0.4 0.055 12.7 0.3 1.3 1 0 0 1 1 1 0 Tetraspanin family Corona_S2 PF01601.11 KEG06480.1 - 2.2 6.2 4.6 3.4 5.6 3.2 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein FAM163 PF15069.1 KEG06480.1 - 2.6 8.6 4.7 6.4 7.3 3.3 1.8 1 1 0 1 1 1 0 FAM163 family Mucin PF01456.12 KEG06480.1 - 2.7 7.7 9.0 0.12 12.1 2.0 2.0 2 1 0 2 2 2 0 Mucin-like glycoprotein Shisa PF13908.1 KEG06481.1 - 0.0022 18.1 0.0 0.0031 17.7 0.0 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF3311 PF11755.3 KEG06481.1 - 0.014 14.9 0.1 0.1 12.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3311) Rhabdo_glycop PF00974.13 KEG06481.1 - 0.075 11.2 0.7 0.11 10.7 0.5 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Prominin PF05478.6 KEG06481.1 - 0.17 9.4 3.4 0.21 9.0 2.3 1.1 1 0 0 1 1 1 0 Prominin Tetraspannin PF00335.15 KEG06481.1 - 0.19 10.9 7.3 0.28 10.4 5.0 1.2 1 0 0 1 1 1 0 Tetraspanin family UPF0370 PF13980.1 KEG06481.1 - 0.38 10.5 4.3 0.98 9.2 3.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) TMEM52 PF14979.1 KEG06481.1 - 0.77 9.6 3.5 1.3 8.9 2.5 1.3 1 0 0 1 1 1 0 Transmembrane 52 Corona_S2 PF01601.11 KEG06481.1 - 1.9 6.4 10.1 2.7 5.9 7.0 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein BDV_P10 PF06515.6 KEG06482.1 - 0.042 13.6 4.4 0.077 12.8 1.1 2.5 2 0 0 2 2 2 0 Borna disease virus P10 protein Sec2p PF06428.6 KEG06482.1 - 0.059 13.2 2.0 0.24 11.2 0.3 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Ribosomal_L22 PF00237.14 KEG06482.1 - 0.11 12.4 0.9 0.36 10.8 0.4 2.1 1 1 0 1 1 1 0 Ribosomal protein L22p/L17e PTSIIB_sorb PF03830.10 KEG06482.1 - 0.12 12.2 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 PTS system sorbose subfamily IIB component Mucin PF01456.12 KEG06482.1 - 0.3 10.8 18.6 1.5 8.6 12.6 2.5 1 1 0 1 1 1 0 Mucin-like glycoprotein Ead_Ea22 PF13935.1 KEG06482.1 - 3.1 8.1 8.3 0.52 10.6 2.9 1.9 2 1 0 2 2 2 0 Ead/Ea22-like protein SpaB_C PF14028.1 KEG06482.1 - 9.6 5.6 8.6 13 5.2 5.7 1.5 1 1 0 1 1 1 0 SpaB C-terminal domain Mucin PF01456.12 KEG06483.1 - 0.00068 19.4 3.4 0.00068 19.4 2.4 4.0 3 1 0 3 3 3 1 Mucin-like glycoprotein Gastrin PF00918.12 KEG06483.1 - 1.6 9.5 11.6 4.2 8.2 0.3 3.2 3 0 0 3 3 3 0 Gastrin/cholecystokinin family Tom5 PF10642.4 KEG06483.1 - 1.9 8.2 6.8 0.34 10.5 1.2 2.5 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase Spore_SspJ PF09575.5 KEG06485.1 - 0.098 12.8 0.2 0.16 12.1 0.1 1.4 1 1 0 1 1 1 0 Small spore protein J (Spore_SspJ) DUF848 PF05852.6 KEG06486.1 - 0.0033 17.2 5.4 0.0035 17.1 3.7 1.0 1 0 0 1 1 1 1 Gammaherpesvirus protein of unknown function (DUF848) Flu_NS2 PF00601.14 KEG06486.1 - 0.0093 16.1 0.5 0.011 15.9 0.4 1.3 1 0 0 1 1 1 1 Influenza non-structural protein (NS2) MAP65_ASE1 PF03999.7 KEG06486.1 - 0.013 14.1 3.9 0.015 13.9 2.7 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DivIC PF04977.10 KEG06486.1 - 0.021 14.2 4.3 0.021 14.2 3.0 2.0 1 1 1 2 2 2 0 Septum formation initiator DUF2031 PF09592.5 KEG06486.1 - 0.037 13.1 2.9 0.039 13.1 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) DUF948 PF06103.6 KEG06486.1 - 0.1 12.5 1.4 0.11 12.3 1.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF1465 PF07323.7 KEG06486.1 - 0.12 11.9 2.2 0.2 11.1 1.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1465) DUF3154 PF11351.3 KEG06486.1 - 0.15 11.8 3.5 0.088 12.5 1.3 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3154) ADIP PF11559.3 KEG06486.1 - 0.16 11.8 9.6 0.18 11.6 6.7 1.0 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Poty_PP PF08440.5 KEG06486.1 - 0.17 10.8 3.9 0.18 10.8 2.7 1.1 1 0 0 1 1 1 0 Potyviridae polyprotein AAT PF03417.11 KEG06486.1 - 0.21 10.9 2.8 0.2 11.0 2.0 1.1 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase DUF904 PF06005.7 KEG06486.1 - 0.21 11.8 10.5 0.81 10.0 3.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF904) PspB PF06667.7 KEG06486.1 - 0.26 11.2 1.9 9.5 6.2 0.2 2.2 1 1 1 2 2 2 0 Phage shock protein B bZIP_1 PF00170.16 KEG06486.1 - 0.29 11.1 5.4 0.28 11.1 1.2 2.0 1 1 1 2 2 2 0 bZIP transcription factor DUF972 PF06156.8 KEG06486.1 - 0.44 10.9 5.9 0.24 11.7 2.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Atg14 PF10186.4 KEG06486.1 - 0.75 8.6 6.1 0.77 8.6 4.3 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 YlqD PF11068.3 KEG06486.1 - 0.93 9.5 11.8 1.2 9.2 8.1 1.2 1 0 0 1 1 1 0 YlqD protein Uso1_p115_C PF04871.8 KEG06486.1 - 0.95 9.3 5.9 2.2 8.2 4.1 1.5 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region bZIP_2 PF07716.10 KEG06486.1 - 2.1 8.2 14.8 0.35 10.7 4.7 2.6 2 2 0 2 2 2 0 Basic region leucine zipper XhlA PF10779.4 KEG06486.1 - 2.5 8.0 4.9 1.5 8.8 2.0 1.6 1 1 1 2 2 2 0 Haemolysin XhlA IncA PF04156.9 KEG06486.1 - 3.2 7.3 7.3 3.5 7.1 5.0 1.2 1 0 0 1 1 1 0 IncA protein PGK PF00162.14 KEG06488.1 - 7.9e-55 185.9 0.0 4.1e-54 183.6 0.0 1.8 1 1 0 1 1 1 1 Phosphoglycerate kinase PEPcase PF00311.12 KEG06488.1 - 0.039 11.8 0.0 0.057 11.2 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase MgtE_N PF03448.12 KEG06488.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 MgtE intracellular N domain AAA_16 PF13191.1 KEG06489.1 - 4.5e-06 26.7 2.0 5.5e-05 23.2 0.0 3.2 3 1 1 4 4 4 1 AAA ATPase domain AAA_14 PF13173.1 KEG06489.1 - 0.00029 20.7 0.0 0.00051 19.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KEG06489.1 - 0.00081 18.3 0.0 0.0013 17.6 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.7 KEG06489.1 - 0.0028 17.3 0.0 0.13 11.8 0.0 2.6 1 1 1 2 2 2 1 NACHT domain Arch_ATPase PF01637.13 KEG06489.1 - 0.0047 16.6 0.0 0.06 13.0 0.0 2.1 1 1 1 2 2 2 1 Archaeal ATPase AAA_17 PF13207.1 KEG06489.1 - 0.017 15.9 0.0 0.051 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KEG06489.1 - 0.023 14.8 0.1 0.2 11.7 0.0 2.4 2 1 1 3 3 3 0 AAA domain AAA_25 PF13481.1 KEG06489.1 - 0.043 13.2 0.0 0.14 11.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KEG06489.1 - 0.056 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 NTPase DUF258 PF03193.11 KEG06489.1 - 0.1 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 KEG06489.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase LRR_4 PF12799.2 KEG06491.1 - 4.3e-28 96.4 4.0 2.9e-05 23.5 0.0 7.8 6 1 1 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG06491.1 - 3.2e-25 87.6 15.6 2.1e-06 27.3 0.6 5.5 4 1 0 5 5 5 4 Leucine rich repeat LRR_1 PF00560.28 KEG06491.1 - 1.5e-07 30.4 21.3 4.9 7.5 0.1 11.5 9 3 1 10 10 10 2 Leucine Rich Repeat LRR_7 PF13504.1 KEG06491.1 - 1.2e-06 27.7 25.1 7.9 7.1 0.1 11.8 13 0 0 13 13 13 2 Leucine rich repeat LRR_6 PF13516.1 KEG06491.1 - 3.3e-06 26.5 10.2 9.7 6.6 0.0 9.5 10 1 1 11 11 11 1 Leucine Rich repeat DUF1399 PF07173.7 KEG06491.1 - 0.034 14.4 3.5 1.9 8.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1399) Cyclin_N PF00134.18 KEG06492.1 - 0.00013 21.5 0.1 0.0002 20.8 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF4033 PF13225.1 KEG06493.1 - 0.052 13.1 0.0 48 3.6 0.0 3.1 2 1 0 3 3 3 0 Domain of unknown function (DUF4033) PrsW-protease PF13367.1 KEG06493.1 - 0.06 12.5 3.8 6.7 5.8 0.1 3.0 1 1 1 2 2 2 0 Protease prsW family K-box PF01486.12 KEG06495.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 K-box region M20_dimer PF07687.9 KEG06495.1 - 0.071 12.8 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase dimerisation domain zf-CCCH PF00642.19 KEG06498.1 - 5.2e-06 25.9 1.4 8.6e-06 25.3 1.0 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KEG06498.1 - 0.0023 17.8 0.9 0.0041 17.0 0.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type polyprenyl_synt PF00348.12 KEG06498.1 - 0.037 12.8 0.0 0.053 12.3 0.0 1.2 1 0 0 1 1 1 0 Polyprenyl synthetase RRM_5 PF13893.1 KEG06499.1 - 0.0068 16.2 0.6 0.019 14.7 0.4 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PBP1_TM PF14812.1 KEG06499.1 - 7.6 6.9 15.1 0.33 11.2 4.3 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_transf_22 PF03901.12 KEG06500.1 - 1.1e-67 228.8 0.1 2.2e-67 227.9 0.0 1.5 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family RHSP PF07999.6 KEG06502.1 - 7.8e-91 304.8 0.1 1.2e-90 304.1 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon hot spot protein AAA_10 PF12846.2 KEG06502.1 - 0.023 14.1 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain DUF3135 PF11333.3 KEG06503.1 - 0.017 15.2 0.0 0.053 13.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) DUF4416 PF14385.1 KEG06503.1 - 0.048 13.3 0.1 0.1 12.2 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4416) DUF717 PF05338.7 KEG06503.1 - 0.05 13.5 0.6 0.15 12.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF717) Pik1 PF11522.3 KEG06503.1 - 0.097 12.4 0.4 0.98 9.2 0.2 2.5 2 0 0 2 2 2 0 Yeast phosphatidylinositol-4-OH kinase Pik1 DUF2197 PF09963.4 KEG06503.1 - 0.2 11.6 0.0 0.2 11.6 0.0 3.3 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2197) SpoIIID PF12116.3 KEG06504.1 - 0.15 11.9 0.6 0.29 11.1 0.4 1.3 1 0 0 1 1 1 0 Stage III sporulation protein D Xpo1 PF08389.7 KEG06504.1 - 0.19 11.6 1.9 0.24 11.3 0.8 1.4 1 1 0 1 1 1 0 Exportin 1-like protein HAUS6_N PF14661.1 KEG06504.1 - 0.3 10.3 7.9 0.52 9.6 5.5 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF2894 PF11445.3 KEG06504.1 - 2.6 8.2 10.5 0.1 12.8 2.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) WD40 PF00400.27 KEG06505.1 - 6.1e-26 89.3 0.3 1.3e-05 24.8 0.0 6.1 7 0 0 7 7 7 4 WD domain, G-beta repeat Thioredoxin_8 PF13905.1 KEG06507.1 - 1e-15 57.6 0.1 1.6e-15 57.0 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 KEG06507.1 - 6.2e-06 25.9 0.0 8.1e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KEG06507.1 - 0.00094 18.7 0.1 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin BBIP10 PF14777.1 KEG06508.1 - 1.2e-14 53.4 0.4 1.5e-14 53.1 0.3 1.1 1 0 0 1 1 1 1 Cilia BBSome complex subunit 10 IncA PF04156.9 KEG06509.1 - 0.0063 16.1 11.6 0.0063 16.1 8.0 2.5 1 1 0 2 2 2 1 IncA protein Imm42 PF15601.1 KEG06509.1 - 0.014 14.8 0.4 0.72 9.2 0.0 2.3 2 0 0 2 2 2 0 Immunity protein 42 ADIP PF11559.3 KEG06509.1 - 0.016 15.1 7.6 0.016 15.1 5.3 3.2 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding Baculo_PEP_C PF04513.7 KEG06509.1 - 0.058 13.2 0.2 0.11 12.3 0.2 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 KEG06509.1 - 0.11 11.1 12.6 0.023 13.3 3.1 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein AAA_13 PF13166.1 KEG06509.1 - 0.82 8.0 6.2 1.3 7.3 4.0 1.4 1 1 0 1 1 1 0 AAA domain ATG16 PF08614.6 KEG06509.1 - 1.2 8.9 17.8 0.072 12.9 6.6 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) COG2 PF06148.6 KEG06509.1 - 2.4 8.0 9.8 6 6.7 1.8 3.0 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 TBPIP PF07106.8 KEG06509.1 - 5.7 6.4 12.2 1.4 8.3 3.0 3.1 1 1 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mucin PF01456.12 KEG06510.1 - 1.9e-05 24.4 6.5 1.9e-05 24.4 4.5 4.0 1 1 2 3 3 3 2 Mucin-like glycoprotein DUF573 PF04504.9 KEG06511.1 - 0.079 13.2 0.2 0.35 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF573 Transpep_BrtH PF14399.1 KEG06511.1 - 0.23 10.6 4.7 3.1 7.0 0.1 2.1 1 1 1 2 2 2 0 NlpC/p60-like transpeptidase BMFP PF04380.8 KEG06511.1 - 0.52 10.4 4.7 0.31 11.1 0.5 2.5 1 1 1 2 2 2 0 Membrane fusogenic activity Hemerythrin PF01814.18 KEG06511.1 - 0.55 10.3 4.0 2.2 8.4 0.2 2.6 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain DASH_Dad2 PF08654.5 KEG06511.1 - 1.2 9.1 5.9 0.75 9.8 0.3 2.5 1 1 0 2 2 2 0 DASH complex subunit Dad2 Sec23_trunk PF04811.10 KEG06512.1 - 1.3e-45 155.6 0.0 3.1e-45 154.4 0.0 1.6 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KEG06512.1 - 5.5e-28 96.4 0.1 1e-27 95.5 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KEG06512.1 - 9.2e-21 74.1 0.1 2e-20 73.0 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KEG06512.1 - 5.5e-06 25.8 7.9 1.4e-05 24.5 5.5 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KEG06512.1 - 1.2e-05 24.8 0.0 3e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat OrfB_Zn_ribbon PF07282.6 KEG06512.1 - 0.092 12.4 0.8 0.19 11.3 0.6 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Prok-RING_1 PF14446.1 KEG06512.1 - 1.4 8.7 4.6 3.4 7.4 3.2 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-CCHC PF00098.18 KEG06513.1 - 0.0008 19.2 2.3 0.0012 18.6 1.6 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 KEG06513.1 - 0.013 15.2 2.0 0.021 14.5 1.4 1.3 1 0 0 1 1 1 0 Zinc knuckle Adaptin_N PF01602.15 KEG06517.1 - 2.2e-71 240.7 6.8 3.1e-71 240.2 4.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 KEG06517.1 - 8.5e-46 154.8 0.3 5.3e-45 152.3 0.2 2.4 1 1 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 KEG06517.1 - 2.3e-38 131.0 0.0 5.1e-38 129.8 0.0 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 KEG06517.1 - 6e-09 36.0 12.1 0.00034 20.8 0.4 6.0 3 1 2 5 5 5 2 HEAT repeats HEAT PF02985.17 KEG06517.1 - 2.2e-05 24.1 2.7 0.47 10.6 0.0 4.8 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.2 KEG06517.1 - 0.0025 17.6 4.8 3.1 7.6 0.0 3.8 2 2 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Arm_2 PF04826.8 KEG06517.1 - 0.018 14.1 0.5 0.73 8.8 0.1 2.6 1 1 1 2 2 2 0 Armadillo-like U3snoRNP10 PF12397.3 KEG06517.1 - 0.044 13.7 2.4 11 5.9 0.5 3.7 3 0 0 3 3 3 0 U3 small nucleolar RNA-associated protein 10 DUF2019 PF09450.5 KEG06517.1 - 0.054 13.3 0.5 9.4 6.1 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF2019) HEAT_EZ PF13513.1 KEG06517.1 - 0.055 13.9 4.4 1.7 9.1 0.0 4.9 4 1 1 5 5 4 0 HEAT-like repeat Ipi1_N PF12333.3 KEG06517.1 - 0.089 12.7 0.9 15 5.6 0.0 3.2 2 1 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation ComC PF03047.9 KEG06517.1 - 0.77 9.2 2.4 1.6 8.2 1.7 1.5 1 0 0 1 1 1 0 COMC family RRM_5 PF13893.1 KEG06518.1 - 4.3e-11 42.4 0.0 1e-05 25.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEG06518.1 - 5.6e-09 35.5 0.0 0.0021 17.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG06518.1 - 2.3e-06 27.5 0.0 0.018 15.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Menin PF05053.8 KEG06518.1 - 0.018 13.2 0.9 0.024 12.8 0.7 1.1 1 0 0 1 1 1 0 Menin Ras PF00071.17 KEG06521.1 - 9.4e-55 184.4 2.7 3.9e-54 182.4 1.9 1.7 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KEG06521.1 - 1.4e-23 83.6 0.1 4.1e-23 82.1 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KEG06521.1 - 4.5e-13 48.8 0.0 5.4e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KEG06521.1 - 4.3e-08 32.5 0.0 5.6e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KEG06521.1 - 1.8e-06 27.8 0.0 3.2e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KEG06521.1 - 4.5e-05 22.9 0.1 0.0011 18.4 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain cobW PF02492.14 KEG06521.1 - 7.7e-05 22.2 0.2 0.11 11.9 0.0 2.3 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 KEG06521.1 - 0.0016 18.5 0.0 0.0025 17.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 KEG06521.1 - 0.0084 15.7 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KEG06521.1 - 0.0098 15.6 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase DUF258 PF03193.11 KEG06521.1 - 0.011 14.9 0.1 0.035 13.3 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 KEG06521.1 - 0.012 15.6 0.1 0.015 15.3 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain MobB PF03205.9 KEG06521.1 - 0.015 15.0 0.3 0.049 13.3 0.0 2.1 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 KEG06521.1 - 0.019 14.4 0.4 0.036 13.5 0.1 1.8 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 KEG06521.1 - 0.031 13.7 0.1 0.078 12.3 0.0 1.8 1 1 1 2 2 2 0 AAA-like domain NTPase_1 PF03266.10 KEG06521.1 - 0.036 13.7 0.0 0.071 12.8 0.0 1.5 1 0 0 1 1 1 0 NTPase SRPRB PF09439.5 KEG06521.1 - 0.036 13.2 0.0 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Thyroglobulin_1 PF00086.13 KEG06521.1 - 0.04 13.2 0.1 0.086 12.2 0.0 1.5 1 0 0 1 1 1 0 Thyroglobulin type-1 repeat NACHT PF05729.7 KEG06521.1 - 0.052 13.2 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA PF00004.24 KEG06521.1 - 0.064 13.4 0.1 0.16 12.1 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KEG06521.1 - 0.085 11.6 0.0 0.098 11.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 KEG06521.1 - 0.13 12.4 0.0 0.65 10.2 0.0 2.0 2 0 0 2 2 2 0 RNA helicase Herpes_US9 PF06072.6 KEG06522.1 - 0.54 10.1 2.3 0.43 10.4 0.1 1.8 1 1 1 2 2 2 0 Alphaherpesvirus tegument protein US9 NPBW PF15180.1 KEG06523.1 - 0.013 15.1 0.3 0.046 13.3 0.2 1.9 1 0 0 1 1 1 0 Neuropeptides B and W YdfZ PF14001.1 KEG06523.1 - 0.12 12.6 0.1 0.32 11.2 0.1 1.7 1 0 0 1 1 1 0 YdfZ protein Aa_trans PF01490.13 KEG06524.1 - 1.3e-50 172.1 35.1 1.5e-50 171.9 24.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KEG06524.1 - 8.7e-10 37.9 11.7 8.7e-10 37.9 8.1 2.7 1 1 2 3 3 3 1 Tryptophan/tyrosine permease family SdpI PF13630.1 KEG06524.1 - 0.16 11.7 0.1 0.16 11.7 0.1 5.2 5 1 0 5 5 5 0 SdpI/YhfL protein family Galactosyl_T PF01762.16 KEG06525.1 - 0.00048 19.7 0.0 0.0086 15.6 0.0 2.1 2 0 0 2 2 2 1 Galactosyltransferase OTCace PF00185.19 KEG06527.1 - 0.13 12.0 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Cupin_5 PF06172.6 KEG06529.1 - 5.5e-48 162.4 0.0 6.5e-48 162.1 0.0 1.0 1 0 0 1 1 1 1 Cupin superfamily (DUF985) RE_NgoBV PF09564.5 KEG06529.1 - 0.14 11.3 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 NgoBV restriction endonuclease Mod_r PF07200.8 KEG06530.1 - 1.5e-10 41.2 3.9 1.5e-10 41.2 2.7 1.5 2 0 0 2 2 1 1 Modifier of rudimentary (Mod(r)) protein Microtub_assoc PF07989.6 KEG06530.1 - 0.0003 20.5 1.0 0.00096 18.9 0.7 1.9 1 0 0 1 1 1 1 Microtubule associated FliD_C PF07195.7 KEG06530.1 - 0.0013 18.0 0.4 0.004 16.4 0.0 1.8 2 0 0 2 2 2 1 Flagellar hook-associated protein 2 C-terminus IncA PF04156.9 KEG06530.1 - 0.0017 17.9 4.5 0.0017 17.9 3.1 1.7 2 0 0 2 2 2 1 IncA protein COG7 PF10191.4 KEG06530.1 - 0.0022 16.0 0.5 0.0028 15.6 0.4 1.2 1 0 0 1 1 1 1 Golgi complex component 7 (COG7) DUF869 PF05911.6 KEG06530.1 - 0.0027 16.0 0.3 0.0032 15.7 0.2 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) DMPK_coil PF08826.5 KEG06530.1 - 0.0039 17.0 1.6 0.064 13.1 0.4 2.7 2 0 0 2 2 2 1 DMPK coiled coil domain like CP12 PF02672.10 KEG06530.1 - 0.01 16.2 0.1 0.023 15.1 0.1 1.6 1 0 0 1 1 1 0 CP12 domain Rho_Binding PF08912.6 KEG06530.1 - 0.032 14.5 0.4 0.085 13.1 0.3 1.8 1 0 0 1 1 1 0 Rho Binding PhoU_div PF01865.11 KEG06530.1 - 0.063 12.4 0.7 0.11 11.7 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF47 DivIVA PF05103.8 KEG06530.1 - 0.068 13.2 5.1 0.032 14.3 1.4 2.0 2 0 0 2 2 2 0 DivIVA protein Val_tRNA-synt_C PF10458.4 KEG06530.1 - 0.083 12.9 0.6 0.26 11.3 0.4 1.9 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm DivIC PF04977.10 KEG06530.1 - 0.14 11.7 2.4 0.25 10.8 0.8 2.1 2 0 0 2 2 2 0 Septum formation initiator FlaG PF03646.10 KEG06530.1 - 0.15 12.2 3.0 2.4 8.3 0.1 2.4 2 0 0 2 2 2 0 FlaG protein TSC22 PF01166.13 KEG06530.1 - 0.16 11.9 2.6 0.24 11.4 0.2 2.6 3 1 0 3 3 2 0 TSC-22/dip/bun family Med4 PF10018.4 KEG06530.1 - 0.17 11.2 3.7 1.2 8.5 1.0 2.3 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 TBPIP PF07106.8 KEG06530.1 - 0.19 11.2 3.4 0.41 10.1 1.5 2.0 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Prefoldin_2 PF01920.15 KEG06530.1 - 0.27 11.0 5.9 0.51 10.1 2.5 2.5 3 0 0 3 3 3 0 Prefoldin subunit Syntaxin PF00804.20 KEG06530.1 - 0.3 11.2 3.4 0.28 11.3 0.9 2.0 2 0 0 2 2 2 0 Syntaxin DASH_Dam1 PF08653.5 KEG06530.1 - 0.32 10.7 2.9 2.6 7.8 0.1 3.4 4 0 0 4 4 4 0 DASH complex subunit Dam1 ADIP PF11559.3 KEG06530.1 - 0.34 10.8 4.8 0.18 11.7 1.6 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF904 PF06005.7 KEG06530.1 - 0.36 11.1 5.4 0.37 11.0 2.5 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF904) TPR_MLP1_2 PF07926.7 KEG06530.1 - 0.4 10.4 6.0 0.59 9.8 3.1 2.2 2 1 0 2 2 1 0 TPR/MLP1/MLP2-like protein NPV_P10 PF05531.7 KEG06530.1 - 0.52 10.6 10.0 0.36 11.0 1.1 3.4 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Pox_A_type_inc PF04508.7 KEG06530.1 - 0.52 10.2 3.8 6.5 6.8 0.1 3.5 3 1 0 3 3 3 0 Viral A-type inclusion protein repeat GAS PF13851.1 KEG06530.1 - 0.53 9.4 7.3 0.27 10.3 3.2 2.0 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Seryl_tRNA_N PF02403.17 KEG06530.1 - 0.85 9.6 6.4 0.25 11.3 2.0 2.0 2 1 1 3 3 2 0 Seryl-tRNA synthetase N-terminal domain HALZ PF02183.13 KEG06530.1 - 0.88 9.3 9.6 0.33 10.6 1.5 2.8 3 0 0 3 3 2 0 Homeobox associated leucine zipper DUF4140 PF13600.1 KEG06530.1 - 0.94 9.9 4.2 0.35 11.3 0.7 1.9 2 0 0 2 2 1 0 N-terminal domain of unknown function (DUF4140) SlyX PF04102.7 KEG06530.1 - 1 9.7 5.4 1.4 9.3 2.0 2.5 2 0 0 2 2 2 0 SlyX Mucin PF01456.12 KEG06534.1 - 0.47 10.2 31.6 2.5 7.8 1.8 2.7 2 1 0 2 2 2 0 Mucin-like glycoprotein CC PF04942.9 KEG06535.1 - 1.7 8.5 13.6 0.23 11.3 0.9 3.6 3 0 0 3 3 3 0 CC domain CCDC144C PF14915.1 KEG06537.1 - 0.2 10.5 0.0 0.3 9.9 0.0 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Cpn10 PF00166.16 KEG06538.1 - 6.1e-20 70.9 0.0 6.8e-20 70.8 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Acyl-ACP_TE PF01643.12 KEG06539.1 - 0.00011 21.2 0.1 0.00052 19.0 0.0 2.0 1 1 2 3 3 3 1 Acyl-ACP thioesterase Vicilin_N PF04702.7 KEG06541.1 - 5.7e-06 26.0 1.0 8.6e-06 25.4 0.7 1.2 1 0 0 1 1 1 1 Vicilin N terminal region LST1 PF05083.8 KEG06541.1 - 0.77 9.7 3.5 2.6 8.1 2.5 1.9 1 0 0 1 1 1 0 LST-1 protein Sec2p PF06428.6 KEG06546.1 - 0.0054 16.5 2.5 0.0054 16.5 1.7 2.6 3 0 0 3 3 3 1 GDP/GTP exchange factor Sec2p Sec23_trunk PF04811.10 KEG06546.1 - 0.027 13.8 0.2 0.065 12.5 0.1 1.6 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain IFT57 PF10498.4 KEG06546.1 - 0.032 12.9 6.2 0.5 9.0 0.2 3.0 3 0 0 3 3 3 0 Intra-flagellar transport protein 57 NEP PF10167.4 KEG06546.1 - 0.086 12.5 1.2 0.98 9.1 0.2 2.9 3 0 0 3 3 3 0 Uncharacterised conserved protein FliJ PF02050.11 KEG06547.1 - 6.1 6.9 26.5 0.33 11.0 6.7 3.6 4 0 0 4 4 4 0 Flagellar FliJ protein Thioredoxin PF00085.15 KEG06549.1 - 1e-26 92.6 0.0 5.8e-25 86.9 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 KEG06549.1 - 2.3e-11 43.8 0.0 2e-08 34.4 0.0 2.8 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KEG06549.1 - 1.5e-09 37.7 0.0 2.6e-06 27.4 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin-like Redoxin PF08534.5 KEG06549.1 - 3e-05 23.5 0.0 0.00026 20.5 0.0 2.1 1 1 1 2 2 2 1 Redoxin Thioredoxin_6 PF13848.1 KEG06549.1 - 0.00019 21.3 0.0 0.58 9.9 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_9 PF14595.1 KEG06549.1 - 0.00022 20.7 0.0 0.00049 19.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 KEG06549.1 - 0.00066 19.6 0.0 0.0032 17.4 0.0 2.1 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_5 PF13743.1 KEG06549.1 - 0.038 13.5 0.0 6.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin HyaE PF07449.6 KEG06549.1 - 0.054 13.3 0.0 14 5.6 0.0 2.8 2 1 0 2 2 2 0 Hydrogenase-1 expression protein HyaE NUDIX PF00293.23 KEG06550.1 - 3.2e-07 30.0 0.0 7.3e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain Acyl-CoA_dh_N PF02771.11 KEG06550.1 - 0.4 11.2 2.5 7.6 7.1 0.0 2.8 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase, N-terminal domain ABA_GPCR PF12430.3 KEG06551.1 - 1.5e-16 60.1 2.7 2.9e-16 59.1 1.8 1.4 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 KEG06551.1 - 8.4e-11 41.7 0.0 1.7e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3735) Gln-synt_C PF00120.19 KEG06552.1 - 8.3e-47 159.5 0.0 1.1e-46 159.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 KEG06552.1 - 6.3e-14 51.3 0.0 1.3e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain LRR_8 PF13855.1 KEG06553.1 - 0.099 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Leucine rich repeat DUF2360 PF10152.4 KEG06556.1 - 2.8 8.2 12.8 4.9 7.4 8.9 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) PAT1 PF09770.4 KEG06556.1 - 5.4 5.1 20.4 7.2 4.7 14.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 vMSA PF00695.14 KEG06556.1 - 7.9 5.5 8.2 14 4.7 5.7 1.3 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus DMRL_synthase PF00885.14 KEG06558.1 - 0.053 13.1 0.0 0.061 12.9 0.0 1.1 1 0 0 1 1 1 0 6,7-dimethyl-8-ribityllumazine synthase Amastin PF07344.6 KEG06559.1 - 7.6e-08 32.1 5.7 7.6e-08 32.1 4.0 1.6 1 1 0 1 1 1 1 Amastin surface glycoprotein Peptidase_U4 PF03419.8 KEG06559.1 - 0.46 9.5 5.9 0.16 11.0 2.5 1.4 2 0 0 2 2 2 0 Sporulation factor SpoIIGA Claudin_2 PF13903.1 KEG06559.1 - 1.3 8.6 14.8 0.03 14.0 3.8 2.0 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction RNA_pol_Rpb6 PF01192.17 KEG06560.1 - 3.2e-20 71.6 0.1 4.5e-20 71.1 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 Amastin PF07344.6 KEG06561.1 - 1.2e-08 34.6 8.1 1.8e-08 34.1 5.6 1.3 1 0 0 1 1 1 1 Amastin surface glycoprotein Amastin PF07344.6 KEG06562.1 - 5.7e-08 32.5 2.7 5.7e-08 32.5 1.9 2.0 1 1 1 2 2 2 1 Amastin surface glycoprotein Peptidase_U4 PF03419.8 KEG06562.1 - 1.5 7.8 6.9 1.6 7.7 3.8 1.6 2 0 0 2 2 2 0 Sporulation factor SpoIIGA APP_Cu_bd PF12924.2 KEG06563.1 - 0.048 14.1 0.0 0.099 13.1 0.0 1.5 1 0 0 1 1 1 0 Copper-binding of amyloid precursor, CuBD Metallophos PF00149.23 KEG06564.1 - 2.2e-40 138.1 0.2 2.7e-40 137.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pyr_redox_dim PF02852.17 KEG06565.1 - 3.5e-16 59.1 0.0 4.6e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain zf-TRAF PF02176.13 KEG06566.1 - 0.00042 20.6 10.0 0.016 15.5 1.0 3.2 2 1 1 3 3 3 2 TRAF-type zinc finger zf-TFIIB PF13453.1 KEG06566.1 - 0.017 14.3 0.5 0.017 14.3 0.3 3.2 4 0 0 4 4 4 0 Transcription factor zinc-finger zf-C2H2 PF00096.21 KEG06566.1 - 0.16 12.3 5.2 11 6.6 0.1 4.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-Di19 PF05605.7 KEG06566.1 - 0.29 11.2 9.8 2.8 8.1 1.6 3.6 2 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_2 PF13240.1 KEG06566.1 - 0.36 10.3 7.0 8.8 5.9 0.0 4.0 4 1 0 4 4 4 0 zinc-ribbon domain zf-DNA_Pol PF08996.5 KEG06566.1 - 0.57 9.5 3.9 0.25 10.6 0.8 1.8 1 1 0 1 1 1 0 DNA Polymerase alpha zinc finger Mucin PF01456.12 KEG06567.1 - 1.4e-05 24.8 12.0 1.4e-05 24.8 8.3 4.6 1 1 2 4 4 4 1 Mucin-like glycoprotein Amidohydro_2 PF04909.9 KEG06567.1 - 3.3 7.2 7.4 1.2 8.6 2.1 2.1 2 0 0 2 2 2 0 Amidohydrolase Mucin PF01456.12 KEG06568.1 - 2.1e-07 30.8 44.4 3.7e-07 30.0 2.7 3.4 2 1 0 2 2 2 1 Mucin-like glycoprotein Mucin PF01456.12 KEG06569.1 - 7.8e-05 22.4 27.0 0.00067 19.4 18.7 2.0 1 1 0 1 1 1 1 Mucin-like glycoprotein Seryl_tRNA_N PF02403.17 KEG06569.1 - 0.84 9.6 5.1 0.42 10.6 2.0 1.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Dioxygenase_C PF00775.16 KEG06572.1 - 0.15 11.2 0.3 0.18 11.0 0.2 1.1 1 0 0 1 1 1 0 Dioxygenase Peptidase_M8 PF01457.11 KEG06574.1 - 2.5e-137 458.3 0.3 3.2e-137 458.0 0.2 1.0 1 0 0 1 1 1 1 Leishmanolysin DUF3573 PF12097.3 KEG06575.1 - 4.4 5.7 4.2 6.9 5.1 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3573) Penaeidin PF05927.6 KEG06577.1 - 0.52 10.8 5.0 1.3 9.6 3.5 1.7 1 0 0 1 1 1 0 Penaeidin LRR_4 PF12799.2 KEG06578.1 - 1.8e-15 56.1 2.2 1.2e-08 34.3 1.0 3.7 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG06578.1 - 6.7e-09 35.3 0.4 6.9e-08 32.1 0.1 2.6 3 0 0 3 3 3 1 Leucine rich repeat LRR_9 PF14580.1 KEG06578.1 - 9.4e-09 35.0 0.1 1.6e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_7 PF13504.1 KEG06578.1 - 9.1e-05 22.0 5.2 3.5 8.2 0.1 5.2 5 0 0 5 5 5 1 Leucine rich repeat LRR_1 PF00560.28 KEG06578.1 - 0.0014 18.4 0.6 1.1 9.5 0.0 3.8 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_6 PF13516.1 KEG06578.1 - 0.59 10.3 8.6 5.3 7.4 0.0 4.4 6 0 0 6 6 6 0 Leucine Rich repeat BBIP10 PF14777.1 KEG06578.1 - 0.7 9.3 3.8 0.33 10.3 0.6 2.0 2 0 0 2 2 2 0 Cilia BBSome complex subunit 10 SSB PF00436.20 KEG06579.1 - 8.6e-06 25.5 0.0 1.2e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Single-strand binding protein family tRNA_anti-codon PF01336.20 KEG06579.1 - 0.011 15.6 0.0 0.026 14.3 0.0 1.8 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain RVT_1 PF00078.22 KEG06582.1 - 1.7e-05 24.2 0.0 1.8e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Complex1_LYR_1 PF13232.1 KEG06587.1 - 6.4 7.0 5.5 3.1 8.0 0.0 2.6 3 0 0 3 3 3 0 Complex1_LYR-like Snf7 PF03357.16 KEG06588.1 - 1.2e-33 115.9 29.6 1.2e-33 115.9 20.5 1.8 1 1 1 2 2 2 1 Snf7 DUF2634 PF10934.3 KEG06588.1 - 0.032 13.9 0.4 0.063 13.0 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2634) DUF2072 PF09845.4 KEG06588.1 - 0.06 13.2 0.5 0.06 13.2 0.3 2.4 2 1 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) VanY PF02557.12 KEG06588.1 - 2 8.2 6.1 5.7 6.8 0.9 2.2 1 1 1 2 2 2 0 D-alanyl-D-alanine carboxypeptidase DUF948 PF06103.6 KEG06588.1 - 2.8 7.8 8.4 12 5.8 0.6 2.5 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Cytochrom_B562 PF07361.6 KEG06588.1 - 7.5 7.0 25.1 1 9.8 1.2 4.0 3 2 0 3 3 3 0 Cytochrome b562 Pigment_DH PF06324.6 KEG06590.1 - 0.17 11.1 0.0 0.4 9.9 0.0 1.6 1 0 0 1 1 1 0 Pigment-dispersing hormone (PDH) PhyH PF05721.8 KEG06591.1 - 4.1e-36 125.0 0.0 5.8e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF563 PF04577.9 KEG06592.1 - 7.2e-13 48.9 0.0 1.1e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Ferric_reduct PF01794.14 KEG06593.1 - 3.6e-13 49.6 7.8 3.6e-13 49.6 5.4 2.3 1 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KEG06593.1 - 1.5e-11 44.0 0.0 3e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KEG06593.1 - 1.9e-11 44.1 0.0 1.2e-08 35.0 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.19 KEG06593.1 - 0.00017 21.6 0.0 0.00029 20.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KEG06593.1 - 0.00025 21.6 0.0 0.17 12.4 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain FtsA PF14450.1 KEG06596.1 - 0.095 12.5 8.1 0.59 9.9 1.5 2.8 1 1 1 2 2 2 0 Cell division protein FtsA MGC-24 PF05283.6 KEG06596.1 - 6.3 6.5 11.3 10 5.8 7.2 1.8 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) MIP PF00230.15 KEG06599.1 - 5.5e-32 111.0 9.1 8.6e-32 110.4 6.3 1.3 1 0 0 1 1 1 1 Major intrinsic protein TPR_19 PF14559.1 KEG06600.1 - 0.0031 17.7 0.3 12 6.3 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEG06600.1 - 0.097 12.5 0.4 12 5.9 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.15 KEG06600.1 - 0.43 10.6 2.1 14 5.9 0.0 4.2 6 0 0 6 6 6 0 PPR repeat DUF2413 PF10310.4 KEG06602.1 - 0.1 11.3 11.0 0.17 10.6 7.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Retinal PF15449.1 KEG06603.1 - 1.9 6.0 20.6 2.7 5.5 14.3 1.2 1 0 0 1 1 1 0 Retinal protein WAK_assoc PF14380.1 KEG06604.1 - 0.65 10.5 5.5 1.1 9.7 3.8 1.4 1 1 0 1 1 1 0 Wall-associated receptor kinase C-terminal NID PF07292.8 KEG06605.1 - 0.16 12.0 0.5 4.4 7.4 0.5 2.0 1 1 1 2 2 2 0 Nmi/IFP 35 domain (NID) Mucin PF01456.12 KEG06606.1 - 0.0047 16.7 20.4 0.0047 16.7 14.1 5.5 1 1 2 3 3 3 1 Mucin-like glycoprotein Tropomyosin PF00261.15 KEG06607.1 - 0.0049 15.9 3.9 0.0049 15.9 2.7 2.8 2 1 0 2 2 2 1 Tropomyosin ATP-synt_B PF00430.13 KEG06607.1 - 0.021 14.6 8.9 0.021 14.6 6.1 4.1 2 1 2 4 4 4 0 ATP synthase B/B' CF(0) UBN_AB PF14075.1 KEG06607.1 - 1.4 8.5 5.3 0.41 10.2 1.4 1.8 2 0 0 2 2 2 0 Ubinuclein conserved middle domain Red1 PF07964.6 KEG06607.1 - 4.7 5.2 8.6 6.1 4.8 5.9 1.2 1 0 0 1 1 1 0 Rec10 / Red1 VSP PF03302.8 KEG06609.1 - 0.0064 15.1 0.1 0.012 14.3 0.0 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein CD34_antigen PF06365.7 KEG06609.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Pro_isomerase PF00160.16 KEG06610.1 - 7.9e-38 130.0 0.0 4.1e-37 127.7 0.0 1.9 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-CCCH PF00642.19 KEG06611.1 - 0.0044 16.6 38.5 0.039 13.6 1.1 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) UBA PF00627.26 KEG06611.1 - 0.059 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 UBA/TS-N domain Harakiri PF15196.1 KEG06612.1 - 0.31 11.3 3.9 0.29 11.3 1.8 1.7 1 1 0 1 1 1 0 Activator of apoptosis harakiri RRM_1 PF00076.17 KEG06613.1 - 3.6e-21 74.5 0.0 4.6e-15 55.0 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG06613.1 - 1.5e-14 53.7 0.0 3.3e-08 33.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG06613.1 - 2.8e-05 23.8 0.2 0.016 15.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 KEG06614.1 - 5.1e-08 32.4 4.4 8.4e-08 31.7 3.0 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KEG06614.1 - 0.0073 16.2 1.9 0.0085 16.0 0.3 1.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type Zn_Tnp_IS1 PF03811.8 KEG06614.1 - 0.48 9.9 5.1 4.1 6.9 1.5 2.4 2 0 0 2 2 2 0 InsA N-terminal domain DUF3276 PF11680.3 KEG06615.1 - 0.092 12.5 0.3 0.14 11.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3276) IncA PF04156.9 KEG06615.1 - 0.59 9.6 6.2 0.24 10.9 2.0 1.7 2 0 0 2 2 2 0 IncA protein Pkinase PF00069.20 KEG06616.1 - 1.6e-65 220.8 0.0 2.4e-65 220.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG06616.1 - 1.6e-45 155.2 0.0 2.2e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG06616.1 - 0.0062 15.5 0.0 0.018 14.0 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Met_10 PF02475.11 KEG06617.1 - 1.7e-46 158.3 0.1 3.7e-33 114.8 0.0 2.3 1 1 0 2 2 2 2 Met-10+ like-protein Methyltransf_26 PF13659.1 KEG06617.1 - 6.2e-05 22.9 0.2 0.00015 21.7 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KEG06617.1 - 0.0017 17.5 0.0 0.0031 16.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TRM PF02005.11 KEG06617.1 - 0.0025 16.8 0.0 0.0034 16.3 0.0 1.2 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase AFT PF08731.6 KEG06617.1 - 0.023 14.8 0.2 0.038 14.1 0.1 1.3 1 0 0 1 1 1 0 Transcription factor AFT zf-Di19 PF05605.7 KEG06618.1 - 1.6e-08 34.5 8.6 0.0034 17.4 0.0 4.1 4 0 0 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 KEG06618.1 - 0.00024 21.2 21.2 0.72 10.3 0.1 4.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KEG06618.1 - 0.038 14.0 7.1 3.3 7.8 0.1 4.1 2 2 0 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KEG06618.1 - 0.04 14.0 3.2 33 4.7 0.0 4.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 KEG06618.1 - 0.16 12.3 22.1 0.74 10.2 0.0 4.4 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-met2 PF12907.2 KEG06618.1 - 0.21 11.5 8.0 2.9 7.9 0.0 4.0 4 0 0 4 4 4 0 Zinc-binding zf-H2C2_5 PF13909.1 KEG06618.1 - 0.67 10.3 0.1 0.67 10.3 0.1 4.3 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-met PF12874.2 KEG06618.1 - 0.89 9.8 7.2 14 6.0 0.0 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Sgf11 PF08209.6 KEG06618.1 - 1.3 8.3 0.0 1.3 8.3 0.0 3.7 4 0 0 4 4 4 0 Sgf11 (transcriptional regulation protein) zf-H2C2_2 PF13465.1 KEG06618.1 - 4 7.9 22.4 6.8 7.1 0.1 6.5 7 0 0 7 7 6 0 Zinc-finger double domain C1_2 PF03107.11 KEG06618.1 - 8.2 6.6 7.2 17 5.6 0.1 3.1 3 0 0 3 3 3 0 C1 domain RNase_H PF00075.19 KEG06619.1 - 1.6e-13 51.1 0.0 2.4e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 RNase H Herpes_UL49_2 PF04823.7 KEG06619.1 - 0.044 13.7 0.5 5.6 7.0 0.0 2.5 1 1 1 2 2 2 0 Herpesvirus UL49 tegument protein SMN PF06003.7 KEG06619.1 - 1.1 8.3 3.6 1.8 7.5 2.5 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Ectatomin PF06457.6 KEG06624.1 - 0.082 12.6 0.3 0.21 11.2 0.2 1.7 1 0 0 1 1 1 0 Ectatomin RNA_pol_N PF01194.12 KEG06626.1 - 9e-26 89.6 0.2 1e-25 89.4 0.1 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 KEG06626.1 - 0.15 12.1 0.7 0.33 11.0 0.5 1.6 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) DUF155 PF02582.9 KEG06627.1 - 3.1e-38 131.4 0.0 4.4e-38 130.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Mid2 PF04478.7 KEG06629.1 - 1.7e-09 37.2 0.8 2.9e-09 36.5 0.5 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor SKG6 PF08693.5 KEG06629.1 - 0.00076 18.7 1.6 0.00076 18.7 1.1 1.7 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Protocadherin PF08374.6 KEG06629.1 - 0.064 12.8 0.0 0.09 12.4 0.0 1.2 1 0 0 1 1 1 0 Protocadherin NCU-G1 PF15065.1 KEG06629.1 - 0.14 10.8 0.4 0.21 10.2 0.3 1.2 1 0 0 1 1 1 0 Lysosomal transcription factor, NCU-G1 Adeno_E3_CR2 PF02439.10 KEG06629.1 - 3.2 7.3 8.7 5.7 6.5 6.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 zf-Di19 PF05605.7 KEG06631.1 - 1.2e-06 28.5 2.3 0.33 11.0 0.0 3.2 3 0 0 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 KEG06631.1 - 1.4e-06 28.2 8.0 0.11 12.9 1.3 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KEG06631.1 - 0.00036 20.6 8.5 0.51 10.7 0.0 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KEG06631.1 - 0.0061 16.7 13.4 0.56 10.6 1.5 4.6 4 1 0 4 4 4 2 Zinc-finger double domain zf-met2 PF12907.2 KEG06631.1 - 0.053 13.5 1.3 6.4 6.8 0.0 3.4 3 1 0 3 3 3 0 Zinc-binding zf-C2H2_jaz PF12171.3 KEG06631.1 - 0.058 13.5 0.0 21 5.4 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KEG06631.1 - 0.12 12.5 0.2 10 6.5 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 KEG06631.1 - 0.15 12.3 0.1 0.15 12.3 0.0 3.5 4 0 0 4 4 4 0 C2H2-type zinc-finger domain DUF3552 PF12072.3 KEG06634.1 - 0.00016 20.9 8.6 0.00023 20.4 6.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) Allexi_40kDa PF05549.6 KEG06634.1 - 0.008 15.5 0.1 0.0089 15.3 0.1 1.0 1 0 0 1 1 1 1 Allexivirus 40kDa protein Spc7 PF08317.6 KEG06634.1 - 0.11 11.1 5.6 0.13 10.9 3.9 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3584 PF12128.3 KEG06634.1 - 0.71 7.1 10.2 0.79 6.9 7.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Phage_Mu_F PF04233.9 KEG06634.1 - 1.3 9.5 9.3 0.35 11.4 2.1 2.0 1 1 1 2 2 2 0 Phage Mu protein F like protein DUF4200 PF13863.1 KEG06634.1 - 1.6 8.6 10.4 2.7 7.9 7.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) OmpH PF03938.9 KEG06634.1 - 1.7 8.5 7.4 2.7 7.8 5.2 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DivIVA PF05103.8 KEG06634.1 - 1.8 8.6 7.9 2.5 8.1 5.5 1.2 1 0 0 1 1 1 0 DivIVA protein FUSC PF04632.7 KEG06634.1 - 1.9 6.8 9.4 2 6.7 6.5 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family PV-1 PF06637.6 KEG06634.1 - 6.3 5.2 9.9 6.8 5.1 6.8 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Unstab_antitox PF09720.5 KEG06634.1 - 7.4 6.3 15.6 0.1 12.2 2.5 3.0 2 1 1 3 3 3 0 Putative addiction module component Plus-3 PF03126.13 KEG06636.1 - 1.3e-11 44.4 0.0 2.5e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Plus-3 domain zf-C3HC4_3 PF13920.1 KEG06636.1 - 4.1e-08 32.7 20.9 6.5e-08 32.1 14.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Vps39_2 PF10367.4 KEG06636.1 - 0.0072 16.4 5.2 0.016 15.3 3.6 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-C3HC4_2 PF13923.1 KEG06636.1 - 2.3 8.3 22.4 4.7 7.3 15.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.11 KEG06636.1 - 4.1 7.3 16.3 12 5.8 11.3 1.9 1 1 0 1 1 1 0 FYVE-type zinc finger Galactosyl_T PF01762.16 KEG06639.1 - 0.00042 19.9 0.0 0.78 9.3 0.0 3.6 2 1 1 3 3 3 2 Galactosyltransferase Galactosyl_T PF01762.16 KEG06640.1 - 2e-05 24.2 0.0 0.54 9.8 0.0 3.6 3 1 1 4 4 4 3 Galactosyltransferase PEX11 PF05648.9 KEG06640.1 - 0.16 11.1 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) V-SNARE_C PF12352.3 KEG06641.1 - 1.9e-09 37.4 4.5 2.7e-09 36.9 3.1 1.2 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KEG06641.1 - 1.5e-08 34.2 3.3 2e-08 33.8 2.3 1.2 1 0 0 1 1 1 1 Sec20 OAD_gamma PF04277.8 KEG06641.1 - 0.0017 18.7 0.2 0.0053 17.0 0.0 1.8 2 0 0 2 2 2 1 Oxaloacetate decarboxylase, gamma chain DUF3485 PF11984.3 KEG06641.1 - 0.0026 16.8 0.1 0.0039 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3485) DUF2142 PF09913.4 KEG06641.1 - 0.0043 15.7 0.4 0.0058 15.3 0.3 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2142) Choline_transpo PF04515.7 KEG06641.1 - 0.0049 15.6 0.0 0.0058 15.4 0.0 1.1 1 0 0 1 1 1 1 Plasma-membrane choline transporter OapA_N PF08525.6 KEG06641.1 - 0.013 15.1 1.5 0.026 14.2 1.1 1.5 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif MSC PF09402.5 KEG06641.1 - 0.015 13.9 1.7 0.017 13.8 1.2 1.1 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain TMP_2 PF06791.8 KEG06641.1 - 0.016 14.7 2.2 0.02 14.5 1.6 1.1 1 0 0 1 1 1 0 Prophage tail length tape measure protein DUF3753 PF12575.3 KEG06641.1 - 0.019 14.7 2.4 0.019 14.7 1.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) OppC_N PF12911.2 KEG06641.1 - 0.021 14.1 0.4 0.03 13.6 0.3 1.2 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF2116 PF09889.4 KEG06641.1 - 0.033 13.9 0.8 0.055 13.2 0.5 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF3763 PF12592.3 KEG06641.1 - 0.048 13.3 0.3 0.074 12.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3763) TMEM154 PF15102.1 KEG06641.1 - 0.085 12.5 4.4 0.11 12.2 3.1 1.2 1 0 0 1 1 1 0 TMEM154 protein family DUF1510 PF07423.6 KEG06641.1 - 0.087 12.1 0.5 0.087 12.1 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1510) APG17 PF04108.7 KEG06641.1 - 0.092 11.5 2.2 0.11 11.2 1.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 YukC PF10140.4 KEG06641.1 - 0.092 11.3 1.1 0.1 11.1 0.7 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Wzz PF02706.10 KEG06641.1 - 0.096 12.5 0.1 0.19 11.5 0.0 1.5 2 0 0 2 2 2 0 Chain length determinant protein HSCB_C PF07743.8 KEG06641.1 - 0.11 12.9 2.7 0.16 12.4 1.8 1.3 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain Synaptobrevin PF00957.16 KEG06641.1 - 0.11 12.1 10.2 0.09 12.3 4.9 2.1 1 1 1 2 2 2 0 Synaptobrevin DUF2207 PF09972.4 KEG06641.1 - 0.12 10.9 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF912 PF06024.7 KEG06641.1 - 0.14 12.2 2.7 0.25 11.4 1.9 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) SNARE PF05739.14 KEG06641.1 - 0.17 11.6 4.5 1.1 9.0 0.3 2.2 2 0 0 2 2 2 0 SNARE domain ATP-synt_8 PF00895.15 KEG06641.1 - 0.19 11.9 1.0 0.35 11.1 0.1 1.9 2 0 0 2 2 1 0 ATP synthase protein 8 gpUL132 PF11359.3 KEG06641.1 - 0.23 10.7 1.7 0.29 10.4 1.2 1.1 1 0 0 1 1 1 0 Glycoprotein UL132 tRNA_anti-like PF12869.2 KEG06641.1 - 0.24 10.8 1.4 0.57 9.6 0.0 2.0 2 0 0 2 2 2 0 tRNA_anti-like Rifin_STEVOR PF02009.11 KEG06641.1 - 0.24 11.0 3.8 0.33 10.5 2.7 1.2 1 0 0 1 1 1 0 Rifin/stevor family Laminin_II PF06009.7 KEG06641.1 - 0.34 10.6 4.1 0.47 10.2 2.8 1.2 1 0 0 1 1 1 0 Laminin Domain II SpoIIIAH PF12685.2 KEG06641.1 - 0.49 9.8 5.6 0.55 9.6 0.0 2.5 2 1 0 2 2 2 0 SpoIIIAH-like protein HisKA_3 PF07730.8 KEG06641.1 - 0.53 10.6 2.9 5.1 7.5 0.7 2.2 1 1 1 2 2 2 0 Histidine kinase GP41 PF00517.12 KEG06641.1 - 0.76 9.2 4.3 2 7.9 3.0 1.7 1 1 0 1 1 1 0 Retroviral envelope protein Baculo_11_kDa PF06143.6 KEG06641.1 - 0.8 9.1 3.8 1.3 8.4 2.7 1.6 1 1 0 1 1 1 0 Baculovirus 11 kDa family Spc7 PF08317.6 KEG06641.1 - 1.1 7.8 5.7 1.3 7.6 3.9 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 KEG06641.1 - 1.2 8.6 9.5 1.1 8.7 0.6 2.4 1 1 1 2 2 2 0 IncA protein Shisa PF13908.1 KEG06641.1 - 1.5 8.9 3.4 0.82 9.8 0.7 1.7 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator DUF3552 PF12072.3 KEG06641.1 - 2.6 7.2 10.0 2.8 7.0 4.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Corona_S2 PF01601.11 KEG06641.1 - 3.2 5.7 5.2 4.9 5.1 3.6 1.4 1 1 0 1 1 1 0 Coronavirus S2 glycoprotein BRCT PF00533.21 KEG06642.1 - 1.5e-06 28.2 0.0 2.8e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KEG06642.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 twin BRCT domain DUF2244 PF10003.4 KEG06643.1 - 0.12 11.7 1.2 0.14 11.5 0.9 1.1 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) DUF4131 PF13567.1 KEG06643.1 - 0.29 10.5 2.5 0.29 10.5 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) PAT1 PF09770.4 KEG06645.1 - 1.7 6.7 61.2 2.3 6.3 42.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TPR_11 PF13414.1 KEG06647.1 - 3.9e-08 32.8 10.5 3.8e-05 23.2 3.3 2.4 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KEG06647.1 - 4.9e-07 29.1 14.2 0.0083 15.9 0.1 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEG06647.1 - 7.5e-05 22.9 5.0 0.0088 16.3 0.6 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEG06647.1 - 8.5e-05 23.1 3.6 8.5e-05 23.1 2.5 3.5 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KEG06647.1 - 0.00022 21.1 19.8 0.051 13.5 0.3 4.1 3 2 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 KEG06647.1 - 0.0003 20.8 11.6 0.038 14.1 0.2 3.3 1 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KEG06647.1 - 0.00055 20.2 6.4 1.9 9.0 0.0 5.4 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KEG06647.1 - 0.0006 20.2 12.2 0.014 15.9 0.7 4.9 3 1 2 5 5 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 KEG06647.1 - 0.0074 16.4 8.0 0.69 10.2 0.0 4.8 5 1 0 5 5 5 2 Tetratricopeptide repeat His_binding PF02098.11 KEG06647.1 - 0.1 12.4 0.5 0.16 11.7 0.3 1.3 1 0 0 1 1 1 0 Tick histamine binding protein TPR_1 PF00515.23 KEG06647.1 - 0.12 12.0 15.2 0.19 11.3 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 KEG06647.1 - 0.2 11.5 7.0 1.1 9.2 0.0 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat Peptidase_M20 PF01546.23 KEG06648.1 - 6.1e-15 55.2 0.1 1.2e-14 54.3 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 KEG06648.1 - 1e-06 27.7 0.1 1.1e-05 24.3 0.1 2.4 3 0 0 3 3 3 1 M42 glutamyl aminopeptidase M20_dimer PF07687.9 KEG06648.1 - 3.2e-06 26.8 0.0 8.2e-06 25.5 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KEG06648.1 - 0.016 14.9 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 Ras PF00071.17 KEG06650.1 - 0.069 12.5 0.0 0.085 12.2 0.0 1.1 1 0 0 1 1 1 0 Ras family Pkinase PF00069.20 KEG06651.1 - 5.9e-52 176.3 0.0 7.7e-52 176.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG06651.1 - 9.4e-36 123.1 0.0 1.3e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG06651.1 - 2.9e-05 23.1 0.0 4.8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Ion_trans_N PF08412.5 KEG06652.1 - 0.057 12.7 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 Ion transport protein N-terminal EMP70 PF02990.11 KEG06653.1 - 6.8e-120 400.9 16.3 1.1e-119 400.2 10.3 1.9 1 1 0 1 1 1 1 Endomembrane protein 70 DUF4288 PF14119.1 KEG06655.1 - 0.43 10.7 2.7 1.1 9.4 1.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) APG6 PF04111.7 KEG06660.1 - 0.0012 17.9 0.0 0.0012 17.9 0.0 2.1 3 0 0 3 3 3 1 Autophagy protein Apg6 HOOK PF05622.7 KEG06661.1 - 0.027 12.3 10.5 0.037 11.8 7.3 1.1 1 0 0 1 1 1 0 HOOK protein MscS_porin PF12795.2 KEG06661.1 - 0.11 11.7 14.2 0.19 10.9 9.9 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DinB PF05163.7 KEG06661.1 - 0.34 10.6 4.0 0.2 11.3 0.4 2.1 1 1 1 2 2 2 0 DinB family MCC-bdg_PDZ PF10506.4 KEG06661.1 - 0.46 10.3 7.6 0.2 11.4 2.3 2.3 1 1 2 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Syntaxin PF00804.20 KEG06661.1 - 2.5 8.3 6.0 3.9 7.6 0.1 2.4 1 1 2 3 3 3 0 Syntaxin DUF4164 PF13747.1 KEG06661.1 - 2.5 8.2 17.4 0.48 10.5 1.6 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) GAS PF13851.1 KEG06661.1 - 3.8 6.6 10.7 20 4.2 7.5 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding NUDE_C PF04880.8 KEG06661.1 - 8.1 6.7 14.3 0.44 10.9 1.4 3.2 2 1 0 3 3 3 0 NUDE protein, C-terminal conserved region DHO_dh PF01180.16 KEG06662.1 - 9e-38 129.8 0.0 1e-37 129.7 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase F_bP_aldolase PF01116.15 KEG06662.1 - 0.16 11.0 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-II Mucin PF01456.12 KEG06663.1 - 0.0017 18.1 5.5 0.0017 18.1 3.8 3.8 2 1 0 2 2 2 1 Mucin-like glycoprotein IATP PF04568.7 KEG06663.1 - 0.0028 17.6 2.8 0.014 15.4 2.0 2.2 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Cep57_MT_bd PF06657.8 KEG06663.1 - 0.054 13.4 3.8 0.051 13.5 1.4 1.9 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 HR1 PF02185.11 KEG06663.1 - 1.8 8.3 9.3 1.2 8.9 3.2 3.2 2 1 1 3 3 3 0 Hr1 repeat RRF PF01765.14 KEG06663.1 - 2.2 7.7 15.3 1 8.8 3.2 3.4 2 1 1 3 3 3 0 Ribosome recycling factor Phospholip_B PF04916.8 KEG06665.1 - 3.2e-83 279.7 0.1 3.9e-83 279.4 0.1 1.0 1 0 0 1 1 1 1 Phospholipase B Toxin_31 PF08119.6 KEG06667.1 - 0.14 11.7 1.2 0.3 10.6 0.1 2.1 2 0 0 2 2 2 0 Scorpion acidic alpha-KTx toxin family TPR_10 PF13374.1 KEG06668.1 - 0.096 12.6 1.1 0.24 11.3 0.8 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3772 PF12607.3 KEG06668.1 - 0.13 11.9 1.2 3.1 7.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) NEMO PF11577.3 KEG06668.1 - 0.18 11.5 2.6 0.28 10.9 0.6 2.0 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO Kinesin PF00225.18 KEG06669.1 - 5.2e-91 304.8 0.1 7.9e-91 304.2 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain Cep57_CLD_2 PF14197.1 KEG06669.1 - 0.043 13.7 0.5 0.13 12.2 0.4 1.8 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 RFamide_26RFa PF11109.3 KEG06669.1 - 0.11 12.4 0.1 0.3 11.0 0.1 1.7 1 0 0 1 1 1 0 Orexigenic neuropeptide Qrfp/P518 Peptidase_M18 PF02127.10 KEG06670.1 - 4.7e-154 513.0 0.0 5.3e-154 512.8 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 KEG06670.1 - 2.5e-10 39.6 0.0 7.4e-08 31.4 0.0 2.1 1 1 0 1 1 1 1 M42 glutamyl aminopeptidase MIF PF01187.13 KEG06670.1 - 0.1 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Macrophage migration inhibitory factor (MIF) DUF423 PF04241.10 KEG06671.1 - 3.5e-25 87.7 1.4 4.6e-25 87.3 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF423) ATG22 PF11700.3 KEG06671.1 - 0.038 12.4 0.2 0.042 12.3 0.1 1.0 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like Peptidase_M8 PF01457.11 KEG06672.1 - 3.5e-139 464.5 0.0 4.4e-139 464.1 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin Reprolysin_5 PF13688.1 KEG06672.1 - 0.078 12.8 0.2 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Astacin PF01400.19 KEG06672.1 - 0.097 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) DUF3810 PF12725.2 KEG06672.1 - 2 7.2 3.6 0.58 8.9 0.1 1.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3810) DUF4655 PF15548.1 KEG06673.1 - 0.42 9.4 9.0 0.51 9.1 6.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4655) SelP_N PF04592.9 KEG06673.1 - 0.42 9.9 10.0 0.52 9.6 7.0 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CENP-R PF06729.7 KEG06673.1 - 0.58 9.8 3.3 1 9.0 2.0 1.5 2 0 0 2 2 2 0 Kinetochore component, CENP-R Zip PF02535.17 KEG06673.1 - 1.2 8.0 8.5 1.7 7.6 5.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter BAF1_ABF1 PF04684.8 KEG06673.1 - 4.6 5.9 22.4 5.9 5.6 15.5 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF563 PF04577.9 KEG06674.1 - 6.7e-07 29.4 0.0 1.2e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Peptidase_M8 PF01457.11 KEG06676.1 - 7.2e-106 354.5 5.6 4.6e-56 190.2 1.3 2.0 2 0 0 2 2 2 2 Leishmanolysin Reprolysin_5 PF13688.1 KEG06676.1 - 0.00059 19.8 0.1 0.0011 18.9 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M57 PF12388.3 KEG06676.1 - 0.0083 15.4 0.1 0.018 14.4 0.1 1.5 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Peptidase_M10 PF00413.19 KEG06676.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Matrixin Reprolysin_3 PF13582.1 KEG06676.1 - 0.12 12.8 0.1 0.26 11.8 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4463 PF14703.1 KEG06677.1 - 0.012 16.1 0.4 0.012 16.1 0.3 3.7 3 2 0 3 3 3 0 Domain of unknown function (DUF4463) bZIP_1 PF00170.16 KEG06677.1 - 0.025 14.5 0.4 0.025 14.5 0.3 12.4 11 3 1 12 12 12 0 bZIP transcription factor Pox_A_type_inc PF04508.7 KEG06677.1 - 0.054 13.2 0.2 0.054 13.2 0.1 6.2 7 0 0 7 7 7 0 Viral A-type inclusion protein repeat IncA PF04156.9 KEG06677.1 - 5.7 6.4 127.3 0.13 11.8 7.0 8.5 2 2 6 8 8 8 0 IncA protein A_deaminase_N PF08451.6 KEG06678.1 - 9.4 6.3 9.9 1.2 9.1 0.7 3.4 3 2 0 3 3 3 0 Adenosine/AMP deaminase N-terminal Pex14_N PF04695.8 KEG06679.1 - 0.48 10.4 2.9 0.58 10.1 2.0 1.0 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MORN PF02493.15 KEG06680.1 - 8e-18 63.0 18.3 3.4e-07 29.6 0.3 4.8 5 0 0 5 5 5 4 MORN repeat Pkinase PF00069.20 KEG06681.1 - 1.2e-58 198.2 0.0 1.6e-58 197.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG06681.1 - 1.1e-27 96.7 0.0 2e-27 95.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEG06681.1 - 0.0001 22.1 0.7 0.0001 22.1 0.5 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KEG06681.1 - 0.00075 18.6 0.7 0.00075 18.6 0.5 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KEG06681.1 - 0.05 12.9 0.6 0.13 11.6 0.4 1.7 1 0 0 1 1 1 0 RIO1 family CheR PF01739.13 KEG06681.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain MOZ_SAS PF01853.13 KEG06682.1 - 7e-27 93.8 0.0 1.2e-25 89.8 0.0 2.3 1 1 0 1 1 1 1 MOZ/SAS family cNMP_binding PF00027.24 KEG06683.1 - 3.1e-32 110.2 0.1 1e-17 63.6 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.1 KEG06683.1 - 0.017 15.0 0.3 0.43 10.8 0.0 2.9 3 0 0 3 3 3 0 Leucine Rich repeat LRR_4 PF12799.2 KEG06683.1 - 0.037 13.6 0.2 0.4 10.3 0.1 2.4 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) COX17 PF05051.8 KEG06683.1 - 0.084 12.8 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Gin PF10764.4 KEG06683.1 - 0.15 11.7 0.5 0.99 9.1 0.1 2.4 3 0 0 3 3 3 0 Inhibitor of sigma-G Gin DUF607 PF04678.8 KEG06684.1 - 8.6e-20 71.4 0.5 1.3e-19 70.8 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF607 F-actin_cap_A PF01267.12 KEG06685.1 - 1.3e-25 90.0 0.0 4.2e-23 81.7 0.0 3.1 1 1 0 1 1 1 1 F-actin capping protein alpha subunit Ribosomal_60s PF00428.14 KEG06685.1 - 0.21 11.9 4.6 0.13 12.7 0.5 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF3590 PF12148.3 KEG06686.1 - 0.029 13.9 0.0 0.14 11.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3590) RRM_1 PF00076.17 KEG06687.1 - 3.7e-18 64.9 0.0 5.2e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG06687.1 - 1.5e-12 47.2 0.0 2.5e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG06687.1 - 1.9e-09 37.2 0.0 3.1e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAT1 PF09770.4 KEG06687.1 - 6.1 4.9 27.1 6.8 4.8 18.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2477 PF10631.4 KEG06690.1 - 0.0079 16.4 0.0 0.37 11.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2477) KLRAQ PF10205.4 KEG06690.1 - 0.075 13.0 1.0 0.12 12.3 0.1 1.7 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein Mito_fiss_reg PF05308.6 KEG06690.1 - 0.084 12.2 0.8 0.25 10.6 0.5 1.7 1 1 0 1 1 1 0 Mitochondrial fission regulator SWM_repeat PF13753.1 KEG06691.1 - 0.063 12.3 0.0 0.07 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative flagellar system-associated repeat PhosphMutase PF10143.4 KEG06696.1 - 7.7e-60 201.4 0.0 1.1e-59 200.9 0.0 1.2 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.13 KEG06696.1 - 4.6e-21 75.3 0.0 1.5e-20 73.6 0.0 1.8 1 1 0 1 1 1 1 Metalloenzyme superfamily TMF_DNA_bd PF12329.3 KEG06699.1 - 0.0087 15.8 0.6 0.0087 15.8 0.4 5.8 5 2 2 7 7 7 1 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.7 KEG06699.1 - 0.01 15.5 3.9 0.01 15.5 2.7 5.2 5 0 0 5 5 5 0 TPR/MLP1/MLP2-like protein HALZ PF02183.13 KEG06699.1 - 0.4 10.4 0.0 0.4 10.4 0.0 5.9 5 1 1 6 6 6 0 Homeobox associated leucine zipper GAS PF13851.1 KEG06699.1 - 1.3 8.2 45.0 0.093 11.9 1.2 4.7 2 2 2 4 4 4 0 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 KEG06699.1 - 1.4 8.0 18.3 1.6 7.8 0.9 3.7 2 1 2 4 4 4 0 Reovirus sigma C capsid protein Flagellar_rod PF05149.7 KEG06702.1 - 3.7e-112 374.2 28.9 3.7e-112 374.2 20.0 1.9 3 0 0 3 3 3 1 Paraflagellar rod protein SpoIISA_toxin PF14171.1 KEG06702.1 - 0.68 9.1 5.1 0.16 11.1 0.8 1.9 2 0 0 2 2 2 0 Toxin SpoIISA, type II toxin-antitoxin system MutS_III PF05192.13 KEG06702.1 - 4.6 6.9 22.6 1.2e+04 -4.2 15.7 3.2 1 1 0 1 1 1 0 MutS domain III DUF2258 PF10015.4 KEG06705.1 - 0.22 11.3 2.1 8 6.3 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2258) Laminin_II PF06009.7 KEG06705.1 - 0.3 10.8 0.1 0.3 10.8 0.1 4.3 3 1 2 5 5 5 0 Laminin Domain II Syntaxin PF00804.20 KEG06705.1 - 0.84 9.8 12.8 0.9 9.7 2.1 3.3 3 0 0 3 3 3 0 Syntaxin DUF1664 PF07889.7 KEG06705.1 - 2.9 7.7 7.8 2.9 7.7 1.8 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Atg14 PF10186.4 KEG06705.1 - 4.5 6.1 10.6 0.47 9.3 4.2 1.7 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Laminin_I PF06008.9 KEG06706.1 - 0.00042 19.7 21.9 0.0009 18.6 11.7 2.5 1 1 1 2 2 2 2 Laminin Domain I Luteo_P1-P2 PF08467.5 KEG06706.1 - 0.69 8.6 14.1 1 8.1 9.8 1.2 1 0 0 1 1 1 0 Luteovirus RNA polymerase P1-P2/replicase GLE1 PF07817.8 KEG06706.1 - 0.94 8.3 7.9 0.084 11.7 1.0 2.3 2 1 0 2 2 2 0 GLE1-like protein ExbD PF02472.11 KEG06706.1 - 3.5 7.6 20.2 0.12 12.3 1.6 3.3 3 1 0 3 3 3 0 Biopolymer transport protein ExbD/TolR Pput2613-deam PF14427.1 KEG06707.1 - 0.085 12.5 0.1 0.68 9.6 0.0 2.0 2 0 0 2 2 2 0 Pput_2613-like deaminase EphA2_TM PF14575.1 KEG06708.1 - 0.00016 21.9 0.8 0.012 16.0 0.0 2.6 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain CD34_antigen PF06365.7 KEG06708.1 - 0.018 14.6 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family P12 PF12669.2 KEG06708.1 - 0.036 14.2 0.0 0.13 12.4 0.0 2.0 1 0 0 1 1 1 0 Virus attachment protein p12 family DAP10 PF07213.6 KEG06708.1 - 0.04 13.6 0.1 0.56 10.0 0.0 2.4 2 0 0 2 2 2 0 DAP10 membrane protein DUF912 PF06024.7 KEG06708.1 - 0.043 13.8 0.9 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Adeno_E3_CR2 PF02439.10 KEG06708.1 - 0.05 13.1 2.2 0.14 11.7 1.5 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 YajC PF02699.10 KEG06708.1 - 0.055 13.1 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Preprotein translocase subunit FAM163 PF15069.1 KEG06708.1 - 0.086 13.4 0.3 0.27 11.8 0.2 1.9 1 1 0 1 1 1 0 FAM163 family FixQ PF05545.6 KEG06708.1 - 1.4 8.5 3.2 0.97 9.1 0.3 2.1 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ SKG6 PF08693.5 KEG06708.1 - 2.7 7.3 8.1 1.3 8.3 2.1 2.5 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Symplekin_C PF12295.3 KEG06709.1 - 0.00027 20.9 0.0 0.0017 18.3 0.0 2.2 2 0 0 2 2 2 1 Symplekin tight junction protein C terminal Phage_sheath_1 PF04984.9 KEG06709.1 - 0.04 12.3 0.1 0.1 11.0 0.2 1.5 2 0 0 2 2 2 0 Phage tail sheath protein Vps23_core PF09454.5 KEG06710.1 - 2.2e-13 49.5 0.1 4.7e-13 48.5 0.1 1.5 1 0 0 1 1 1 1 Vps23 core domain Spc7 PF08317.6 KEG06710.1 - 9 4.8 9.2 1.7 7.2 1.2 2.4 2 1 0 3 3 3 0 Spc7 kinetochore protein Vps23_core PF09454.5 KEG06711.1 - 6.9e-20 70.4 0.1 2.5e-19 68.6 0.0 1.9 2 0 0 2 2 2 1 Vps23 core domain Methyltransf_18 PF12847.2 KEG06713.1 - 3.9e-14 53.1 0.0 8.3e-14 52.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEG06713.1 - 2.7e-12 46.5 0.0 9.1e-07 28.5 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 KEG06713.1 - 1.4e-11 44.6 0.0 2.5e-05 24.6 0.0 2.6 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.1 KEG06713.1 - 2.4e-10 40.3 0.0 3e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEG06713.1 - 8e-10 39.0 0.0 1.3e-08 35.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEG06713.1 - 1.6e-05 25.1 0.0 7.9e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 KEG06713.1 - 0.0035 16.2 0.0 0.23 10.3 0.0 2.1 2 0 0 2 2 2 1 DREV methyltransferase NodS PF05401.6 KEG06713.1 - 0.018 14.4 0.0 0.069 12.5 0.0 1.7 2 0 0 2 2 2 0 Nodulation protein S (NodS) PCMT PF01135.14 KEG06713.1 - 0.044 13.3 0.0 0.062 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 KEG06713.1 - 0.053 12.6 0.0 0.08 12.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_15 PF09445.5 KEG06713.1 - 0.059 12.9 0.0 0.083 12.4 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase MTS PF05175.9 KEG06713.1 - 0.17 11.2 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_3 PF01596.12 KEG06713.1 - 0.17 10.8 0.0 0.32 10.0 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase Herpes_LMP1 PF05297.6 KEG06714.1 - 0.037 12.9 1.6 0.042 12.7 1.1 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF4367 PF14285.1 KEG06717.1 - 0.2 10.9 2.7 0.49 9.6 1.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4367) LRR_4 PF12799.2 KEG06723.1 - 8.7e-09 34.8 5.2 0.015 14.9 0.1 5.0 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KEG06723.1 - 2.1e-06 27.2 4.3 0.029 14.4 0.0 5.3 5 0 0 5 5 5 1 Leucine Rich repeat LRR_1 PF00560.28 KEG06723.1 - 1.6e-05 24.3 5.8 17 5.9 0.1 5.3 3 2 1 4 4 4 4 Leucine Rich Repeat LRR_8 PF13855.1 KEG06723.1 - 3.5e-05 23.4 8.2 0.062 13.0 0.7 4.0 2 1 4 6 6 6 5 Leucine rich repeat LRR_7 PF13504.1 KEG06723.1 - 0.064 13.4 7.7 31 5.3 0.1 5.7 4 2 2 6 6 6 0 Leucine rich repeat Corona_NS3b PF03053.9 KEG06724.1 - 0.078 12.5 0.2 0.095 12.2 0.1 1.1 1 0 0 1 1 1 0 ORF3b coronavirus protein Cluap1 PF10234.4 KEG06725.1 - 0.022 13.9 0.9 0.022 13.9 0.6 3.0 2 1 0 3 3 3 0 Clusterin-associated protein-1 TPR_16 PF13432.1 KEG06725.1 - 0.2 12.3 0.2 0.2 12.3 0.1 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat Filament PF00038.16 KEG06725.1 - 2.8 7.3 16.3 13 5.1 0.2 2.9 2 1 0 2 2 2 0 Intermediate filament protein GAS PF13851.1 KEG06725.1 - 6.2 5.9 12.6 3.6 6.7 2.3 3.0 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding PP2C_2 PF13672.1 KEG06726.1 - 0.0012 18.2 0.6 0.0012 18.2 0.4 2.1 1 1 1 2 2 2 1 Protein phosphatase 2C Laminin_II PF06009.7 KEG06726.1 - 0.002 17.8 0.4 0.0038 16.9 0.3 1.4 1 0 0 1 1 1 1 Laminin Domain II Apc5 PF12862.2 KEG06726.1 - 1.5 8.7 6.3 6.2 6.7 0.5 2.6 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 5 PDZ_2 PF13180.1 KEG06727.1 - 1.6e-08 34.3 0.0 3.3e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 KEG06727.1 - 0.0046 17.1 0.0 0.01 16.0 0.0 1.6 1 1 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) UPF0564 PF10595.4 KEG06727.1 - 0.09 11.6 2.2 0.12 11.2 1.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 MAP65_ASE1 PF03999.7 KEG06727.1 - 1.6 7.2 7.2 2.1 6.8 5.0 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) TBD PF12845.2 KEG06727.1 - 3.4 7.2 4.9 13 5.4 0.2 2.4 2 0 0 2 2 2 0 TBD domain Prenyltrans_1 PF13243.1 KEG06728.1 - 0.07 13.1 0.0 0.09 12.7 0.0 1.2 1 0 0 1 1 1 0 Prenyltransferase-like DUF2867 PF11066.3 KEG06729.1 - 0.21 11.3 3.4 0.083 12.6 0.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2867) Aa_trans PF01490.13 KEG06732.1 - 1.8e-49 168.3 29.7 2e-49 168.1 20.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KEG06732.1 - 3.2e-06 26.2 10.2 3.2e-06 26.2 7.1 1.9 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family DUF2207 PF09972.4 KEG06732.1 - 2.3 6.6 0.0 2.3 6.6 0.0 3.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) MORN PF02493.15 KEG06735.1 - 3.8e-20 70.3 39.1 5.7e-06 25.7 0.4 7.0 7 0 0 7 7 7 6 MORN repeat SecG PF03840.9 KEG06738.1 - 0.077 12.7 0.3 0.089 12.5 0.2 1.2 1 0 0 1 1 1 0 Preprotein translocase SecG subunit Peripla_BP_6 PF13458.1 KEG06740.1 - 7.4e-09 35.4 0.2 1.6e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 Periplasmic binding protein Birna_RdRp PF04197.7 KEG06741.1 - 0.31 9.0 2.7 0.38 8.7 1.9 1.2 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) DUF342 PF03961.8 KEG06741.1 - 4.7 5.5 15.8 0.21 9.9 5.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF342) WD-3 PF09765.4 KEG06741.1 - 10 5.3 12.5 11 5.1 0.8 2.2 1 1 1 2 2 2 0 WD-repeat region Baculo_PEP_C PF04513.7 KEG06742.1 - 0.47 10.2 11.8 0.49 10.2 0.2 3.6 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DDE_Tnp_4 PF13359.1 KEG06742.1 - 3.4 7.2 6.4 8.4 5.9 0.1 3.0 3 0 0 3 3 3 0 DDE superfamily endonuclease RNase_H PF00075.19 KEG06744.1 - 4.6e-05 23.7 0.0 6e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 RNase H Peripla_BP_6 PF13458.1 KEG06747.1 - 0.00046 19.6 0.5 0.008 15.5 0.0 2.7 3 0 0 3 3 3 1 Periplasmic binding protein PA26 PF04636.8 KEG06748.1 - 7.2e-30 104.0 0.0 5.8e-20 71.4 0.0 2.1 1 1 1 2 2 2 2 PA26 p53-induced protein (sestrin) TraC_F_IV PF11130.3 KEG06749.1 - 1.1 8.6 9.5 0.35 10.2 4.4 1.7 1 1 1 2 2 2 0 F pilus assembly Type-IV secretion system for plasmid transfer WW PF00397.21 KEG06750.1 - 7.5e-30 102.4 37.3 2.7e-12 46.3 1.9 4.9 5 0 0 5 5 5 3 WW domain NDT80_PhoG PF05224.7 KEG06750.1 - 0.022 14.7 0.2 0.046 13.7 0.1 1.5 1 0 0 1 1 1 0 NDT80 / PhoG like DNA-binding family zf-ISL3 PF14690.1 KEG06750.1 - 0.16 12.0 1.7 36 4.4 0.0 3.5 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Pkinase PF00069.20 KEG06751.1 - 3.2e-55 187.0 0.0 4.4e-55 186.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG06751.1 - 2e-36 125.4 0.0 3.9e-36 124.4 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG06751.1 - 1.4e-07 30.7 0.0 3.6e-07 29.4 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.20 KEG06752.1 - 1.8e-55 187.8 0.0 2.5e-55 187.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG06752.1 - 1e-35 123.0 0.0 1.9e-35 122.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG06752.1 - 2.5e-06 26.6 0.0 4.1e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH PF00169.24 KEG06752.1 - 8.9e-06 25.8 0.0 3.4e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 PH domain PH_9 PF15410.1 KEG06752.1 - 0.0013 18.8 0.0 0.0081 16.3 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_4 PF15404.1 KEG06752.1 - 0.089 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain LRR_4 PF12799.2 KEG06753.1 - 2.9e-69 227.7 0.0 0.0016 18.0 0.0 21.1 5 5 18 25 25 25 22 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG06753.1 - 6e-56 186.0 0.0 0.0074 16.0 0.0 15.1 10 4 6 16 16 16 15 Leucine rich repeat LRR_6 PF13516.1 KEG06753.1 - 2e-33 110.6 17.2 0.47 10.6 0.0 22.5 26 0 0 26 26 24 6 Leucine Rich repeat LRR_1 PF00560.28 KEG06753.1 - 1.9e-27 91.0 17.8 13 6.2 0.1 25.7 25 9 2 27 27 26 0 Leucine Rich Repeat Glu-tRNAGln PF02686.10 KEG06753.1 - 4.6e-12 45.5 0.0 24 4.8 0.0 11.1 12 0 0 12 12 12 0 Glu-tRNAGln amidotransferase C subunit LRR_7 PF13504.1 KEG06753.1 - 6.5e-07 28.5 33.2 1.6e+02 3.2 0.1 21.2 24 4 2 26 26 25 0 Leucine rich repeat LRR_5 PF13306.1 KEG06753.1 - 1.5e-06 27.9 0.0 5.4 6.7 0.0 7.3 4 3 1 6 6 6 1 Leucine rich repeats (6 copies) NMU PF02070.10 KEG06753.1 - 4.8e-06 25.9 3.2 5.9 6.5 0.0 7.0 9 0 0 9 9 9 1 Neuromedin U GSCFA PF08885.6 KEG06753.1 - 0.00021 20.9 1.6 99 2.3 0.0 7.4 9 0 0 9 9 9 0 GSCFA family DUF1331 PF07048.6 KEG06753.1 - 0.011 15.2 4.4 1.9e+02 1.6 0.0 7.1 9 0 0 9 9 9 0 Protein of unknown function (DUF1331) GPS PF01825.16 KEG06753.1 - 0.22 11.6 19.6 7 6.8 0.1 8.7 11 0 0 11 11 11 0 Latrophilin/CL-1-like GPS domain TgMIC1 PF11476.3 KEG06753.1 - 0.84 9.1 10.2 24 4.4 0.0 7.6 10 0 0 10 10 10 0 Toxoplasma gondii micronemal protein 1 TgMIC1 Motile_Sperm PF00635.21 KEG06754.1 - 1.9e-08 33.8 0.0 7e-08 32.0 0.0 2.1 1 1 0 1 1 1 1 MSP (Major sperm protein) domain Lipase_3 PF01764.20 KEG06755.1 - 5.4e-16 58.4 0.0 1.1e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 KEG06755.1 - 0.0012 18.7 0.0 0.0023 17.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEG06755.1 - 0.021 14.5 0.0 0.046 13.4 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.9 KEG06755.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) C1_1 PF00130.17 KEG06755.1 - 3.5 7.4 9.5 1.5 8.5 2.9 2.7 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PTS_EIIC PF02378.13 KEG06758.1 - 0.14 10.9 0.0 0.15 10.8 0.0 1.0 1 0 0 1 1 1 0 Phosphotransferase system, EIIC DUF2451 PF10474.4 KEG06760.1 - 9.9e-08 32.0 0.0 1.8e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) DUF2450 PF10475.4 KEG06760.1 - 1.3e-06 27.4 1.0 2.4e-06 26.6 0.3 1.6 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) DAGK_cat PF00781.19 KEG06760.1 - 0.016 14.6 0.0 0.035 13.5 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain RINT1_TIP1 PF04437.8 KEG06760.1 - 0.043 12.3 0.0 0.068 11.7 0.0 1.2 1 0 0 1 1 1 0 RINT-1 / TIP-1 family DUF997 PF06196.7 KEG06760.1 - 0.057 12.9 0.4 0.14 11.6 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF997) NB PF04159.8 KEG06760.1 - 0.19 11.5 0.9 0.91 9.2 0.0 2.4 3 0 0 3 3 3 0 NB glycoprotein CTDII PF01556.13 KEG06766.1 - 3.5e-19 68.4 0.1 1.8e-10 40.5 0.0 3.9 4 0 0 4 4 4 3 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KEG06766.1 - 5.1e-08 32.8 11.6 5.1e-08 32.8 8.0 1.9 2 0 0 2 2 2 1 DnaJ central domain HypA PF01155.14 KEG06766.1 - 1.6 8.4 6.2 33 4.2 4.3 2.3 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family A2L_zn_ribbon PF08792.5 KEG06766.1 - 8 6.0 12.7 2.3 7.7 0.4 3.4 4 0 0 4 4 4 0 A2L zinc ribbon domain CTP_synth_N PF06418.9 KEG06767.1 - 2.4e-109 364.6 0.0 3.6e-109 364.1 0.0 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 KEG06767.1 - 1.1e-41 142.3 0.9 7.3e-35 120.1 0.1 2.4 1 1 1 2 2 2 2 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KEG06767.1 - 8e-13 48.3 0.2 1.4e-08 34.4 0.0 2.9 3 0 0 3 3 3 2 Peptidase C26 CbiA PF01656.18 KEG06767.1 - 0.0012 18.3 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Pkinase PF00069.20 KEG06768.1 - 2e-55 187.7 0.0 3.2e-55 187.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG06768.1 - 1.2e-36 126.1 0.0 2.3e-36 125.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase PX PF00787.19 KEG06768.1 - 0.00058 19.6 0.2 0.00058 19.6 0.1 2.4 3 0 0 3 3 3 1 PX domain Kinase-like PF14531.1 KEG06768.1 - 0.012 14.6 0.0 0.034 13.0 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Peptidase_C2 PF00648.16 KEG06769.1 - 2.7e-13 49.5 0.0 3.9e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 KEG06769.1 - 8.5e-09 35.2 0.0 1.9e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Calpain large subunit, domain III PPO1_DWL PF12142.3 KEG06769.1 - 0.11 12.0 0.3 0.29 10.6 0.2 1.7 1 0 0 1 1 1 0 Polyphenol oxidase middle domain HisKA_3 PF07730.8 KEG06769.1 - 0.39 11.0 4.1 3.1 8.1 0.4 3.4 3 0 0 3 3 3 0 Histidine kinase KfrA_N PF11740.3 KEG06769.1 - 2.9 8.3 8.8 1.4 9.4 0.7 3.2 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term SCAN PF02023.12 KEG06770.1 - 0.14 11.6 1.2 0.27 10.7 0.8 1.5 1 0 0 1 1 1 0 SCAN domain GATase PF00117.23 KEG06771.1 - 1.4e-29 102.9 0.0 3.2e-29 101.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 KEG06771.1 - 4.1e-28 96.9 0.1 1.7e-16 59.7 0.0 2.7 2 1 0 2 2 2 2 GMP synthase C terminal domain Peptidase_C26 PF07722.8 KEG06771.1 - 6.2e-14 51.9 0.0 2.6e-13 49.9 0.0 2.1 1 1 1 2 2 2 1 Peptidase C26 NAD_synthase PF02540.12 KEG06771.1 - 2e-09 36.7 0.0 4.5e-05 22.4 0.0 2.2 2 0 0 2 2 2 2 NAD synthase QueC PF06508.8 KEG06771.1 - 9.1e-06 25.1 0.0 0.00014 21.2 0.0 2.4 2 1 0 2 2 2 1 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.14 KEG06771.1 - 0.00036 19.6 0.0 0.00053 19.1 0.0 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase ThiI PF02568.9 KEG06771.1 - 0.00071 19.0 0.0 0.0033 16.8 0.0 2.1 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.16 KEG06771.1 - 0.0018 17.8 0.3 0.0051 16.3 0.2 1.9 1 1 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.15 KEG06771.1 - 0.0026 17.2 0.0 0.029 13.8 0.0 2.2 2 0 0 2 2 2 1 PP-loop family tRNA_Me_trans PF03054.11 KEG06771.1 - 0.0067 15.0 0.1 0.03 12.8 0.0 1.9 2 0 0 2 2 2 1 tRNA methyl transferase PAPS_reduct PF01507.14 KEG06771.1 - 0.027 14.3 0.0 0.053 13.3 0.0 1.6 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Dak2 PF02734.12 KEG06771.1 - 0.083 12.5 0.3 0.2 11.3 0.2 1.6 1 0 0 1 1 1 0 DAK2 domain GATase_3 PF07685.9 KEG06771.1 - 0.14 11.7 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Inhibitor_I68 PF10468.4 KEG06773.1 - 0.13 12.4 0.9 3.5 7.8 0.3 2.1 1 1 1 2 2 2 0 Carboxypeptidase inhibitor I68 Peptidase_M8 PF01457.11 KEG06775.1 - 9.8e-102 340.9 0.5 1.3e-101 340.5 0.3 1.0 1 0 0 1 1 1 1 Leishmanolysin DUF1935 PF09149.5 KEG06776.1 - 1.3e-24 86.1 0.0 1.5e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.16 KEG06777.1 - 2.5e-22 79.2 0.0 3.9e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 KEG06777.1 - 2.3e-20 72.5 0.0 5.6e-20 71.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) zf-HIT PF04438.11 KEG06778.1 - 8.2e-07 28.5 9.2 1.6e-06 27.6 6.4 1.5 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.13 KEG06778.1 - 0.055 13.3 8.8 0.12 12.2 6.1 1.6 1 0 0 1 1 1 0 MYND finger Adaptin_N PF01602.15 KEG06779.1 - 4.4e-96 322.2 0.3 5.8e-96 321.9 0.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 KEG06779.1 - 4.4e-10 39.6 10.8 0.0034 17.6 0.1 5.4 4 1 1 5 5 5 4 HEAT repeats Cnd1 PF12717.2 KEG06779.1 - 8.7e-07 28.9 0.0 6.7e-06 26.0 0.0 2.5 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KEG06779.1 - 1.2e-05 25.0 2.8 0.32 11.1 0.0 5.7 6 0 0 6 6 6 1 HEAT repeat B2-adapt-app_C PF09066.5 KEG06779.1 - 0.00045 20.0 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain CLASP_N PF12348.3 KEG06779.1 - 0.00048 19.5 0.1 0.17 11.2 0.0 2.5 2 0 0 2 2 2 2 CLASP N terminal HEAT_EZ PF13513.1 KEG06779.1 - 0.01 16.3 6.9 0.28 11.7 0.1 5.3 3 2 3 6 6 6 0 HEAT-like repeat RICTOR_V PF14668.1 KEG06779.1 - 0.054 13.4 0.0 0.33 10.8 0.0 2.3 1 1 1 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 WD40 PF00400.27 KEG06785.1 - 1e-64 212.2 36.0 3.3e-12 45.7 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KEG06785.1 - 4.5e-07 28.4 16.4 0.032 12.3 0.1 4.9 1 1 4 5 5 5 4 Nucleoporin Nup120/160 PH PF00169.24 KEG06786.1 - 2.3e-08 34.1 0.1 4.7e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KEG06786.1 - 0.0031 17.7 0.2 0.072 13.3 0.1 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.1 KEG06786.1 - 0.0034 17.5 1.6 0.0092 16.1 0.0 2.3 3 1 1 4 4 4 1 Pleckstrin homology domain DUF3525 PF12039.3 KEG06786.1 - 0.01 14.4 0.8 0.013 14.0 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) Mcp5_PH PF12814.2 KEG06786.1 - 0.027 14.3 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology DUF334 PF03904.8 KEG06786.1 - 0.1 11.9 3.0 0.14 11.4 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Atg14 PF10186.4 KEG06786.1 - 0.12 11.3 8.7 0.17 10.7 6.1 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Laminin_II PF06009.7 KEG06786.1 - 0.73 9.5 5.8 3.6 7.3 0.1 2.2 1 1 1 2 2 2 0 Laminin Domain II DUF1664 PF07889.7 KEG06786.1 - 1.1 9.0 6.8 0.26 11.1 0.3 2.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Filament PF00038.16 KEG06786.1 - 1.4 8.3 15.6 3.2 7.1 9.6 1.6 1 1 0 1 1 1 0 Intermediate filament protein Seryl_tRNA_N PF02403.17 KEG06786.1 - 1.7 8.7 11.2 1.4 8.9 6.6 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Cortex-I_coil PF09304.5 KEG06786.1 - 7.1 6.7 14.2 2.6 8.1 2.8 2.3 1 1 1 2 2 2 0 Cortexillin I, coiled coil NuA4 PF09340.5 KEG06788.1 - 2.1e-09 36.9 0.0 3.7e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 CP2 PF04516.10 KEG06789.1 - 0.018 14.1 0.1 0.025 13.6 0.1 1.1 1 0 0 1 1 1 0 CP2 transcription factor EF-hand_1 PF00036.27 KEG06795.1 - 4.3e-07 28.7 0.8 1.6e-06 27.0 0.3 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 KEG06795.1 - 3.8e-06 26.3 0.1 4.5e-05 22.9 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 KEG06795.1 - 9.4e-06 25.1 1.0 7.2e-05 22.3 0.1 2.5 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 KEG06795.1 - 1.2e-05 24.3 1.0 6.2e-05 22.1 0.3 2.4 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 KEG06795.1 - 3.7e-05 23.7 0.9 0.00017 21.6 0.1 2.3 2 1 0 2 2 2 1 EF-hand domain pair Mito_fiss_reg PF05308.6 KEG06796.1 - 0.15 11.3 2.3 0.17 11.2 1.6 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF3649 PF12365.3 KEG06797.1 - 0.023 14.1 4.8 0.57 9.7 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3649) Haemolytic PF01809.13 KEG06797.1 - 0.03 13.9 0.2 0.059 12.9 0.1 1.4 1 0 0 1 1 1 0 Haemolytic domain AAA_17 PF13207.1 KEG06800.1 - 4.5e-07 30.7 2.3 1e-06 29.5 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KEG06800.1 - 4.4e-05 23.7 0.2 0.00051 20.3 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 KEG06800.1 - 4.7e-05 23.4 0.0 0.00014 21.9 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 KEG06800.1 - 0.0055 16.8 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KTI12 PF08433.5 KEG06800.1 - 0.0088 15.2 0.0 0.027 13.6 0.0 1.8 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Thymidylate_kin PF02223.12 KEG06800.1 - 0.049 13.0 0.0 0.94 8.8 0.0 2.6 2 0 0 2 2 2 0 Thymidylate kinase DZR PF12773.2 KEG06800.1 - 0.83 9.5 10.2 8.6 6.2 7.1 2.4 1 1 1 2 2 2 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.6 KEG06800.1 - 3.9 7.2 10.6 3.8 7.2 2.1 2.7 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Urocanase PF01175.13 KEG06801.1 - 2.6e-220 732.1 0.2 3.5e-210 698.7 0.0 2.0 1 1 1 2 2 2 2 Urocanase Serglycin PF04360.7 KEG06802.1 - 0.11 12.2 0.5 0.16 11.7 0.3 1.2 1 0 0 1 1 1 0 Serglycin Complex1_LYR_1 PF13232.1 KEG06803.1 - 7.4e-08 32.4 4.5 2.8e-07 30.6 3.2 2.1 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KEG06803.1 - 1.8e-07 30.8 1.0 6.1e-07 29.1 0.1 2.3 1 1 1 2 2 2 1 Complex 1 protein (LYR family) HTH_8 PF02954.14 KEG06803.1 - 0.069 12.6 0.5 7.3 6.2 0.1 2.4 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family PCP_red PF08369.5 KEG06803.1 - 0.11 12.3 1.1 4.6 7.2 0.0 2.7 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit NEMO PF11577.3 KEG06803.1 - 0.18 11.6 4.8 0.39 10.5 3.3 1.6 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO DUF3560 PF12083.3 KEG06803.1 - 1.1 9.3 7.5 3.9 7.5 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3560) ATP_bind_1 PF03029.12 KEG06805.1 - 2.9e-69 233.2 0.0 3.4e-69 233.0 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 KEG06805.1 - 5e-06 26.6 0.0 1.4e-05 25.1 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain GTP_EFTU PF00009.22 KEG06805.1 - 5.4e-06 25.9 0.0 2.6e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.1 KEG06805.1 - 1.8e-05 24.3 0.0 3.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 KEG06805.1 - 2.7e-05 23.7 0.0 0.0005 19.5 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Miro PF08477.8 KEG06805.1 - 4.9e-05 23.8 0.1 0.01 16.3 0.1 2.3 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KEG06805.1 - 0.00014 21.7 0.2 0.00026 20.9 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 KEG06805.1 - 0.00025 20.9 1.1 0.00034 20.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain SRPRB PF09439.5 KEG06805.1 - 0.00028 20.1 0.0 0.56 9.3 0.0 2.2 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit CbiA PF01656.18 KEG06805.1 - 0.00038 19.9 0.0 0.00066 19.1 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 KEG06805.1 - 0.00051 18.9 0.0 0.1 11.3 0.0 2.3 2 0 0 2 2 2 1 ArgK protein AAA_19 PF13245.1 KEG06805.1 - 0.00067 19.3 0.0 0.0021 17.7 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain FeoB_N PF02421.13 KEG06805.1 - 0.00085 18.6 0.1 0.042 13.1 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B AAA_17 PF13207.1 KEG06805.1 - 0.002 18.9 0.1 0.004 17.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 KEG06805.1 - 0.0025 17.9 0.0 0.0049 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 KEG06805.1 - 0.0033 16.8 0.9 0.035 13.5 0.6 2.2 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.13 KEG06805.1 - 0.0033 16.4 0.0 0.011 14.7 0.0 1.8 1 1 0 1 1 1 1 Septin Zeta_toxin PF06414.7 KEG06805.1 - 0.0044 16.1 0.0 0.0077 15.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin PduV-EutP PF10662.4 KEG06805.1 - 0.0052 16.2 0.0 0.049 13.1 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 KEG06805.1 - 0.0054 16.6 0.0 0.0086 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Arf PF00025.16 KEG06805.1 - 0.0072 15.5 0.0 0.067 12.4 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family NACHT PF05729.7 KEG06805.1 - 0.0072 16.0 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain MobB PF03205.9 KEG06805.1 - 0.0082 15.8 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 KEG06805.1 - 0.0083 15.7 0.6 0.021 14.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 KEG06805.1 - 0.012 14.4 0.1 0.019 13.8 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.9 KEG06805.1 - 0.04 13.6 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 KEG06805.1 - 0.043 13.5 0.1 0.095 12.4 0.0 1.5 1 1 0 1 1 1 0 NTPase IstB_IS21 PF01695.12 KEG06805.1 - 0.051 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 KEG06805.1 - 0.075 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_25 PF13481.1 KEG06805.1 - 0.077 12.3 0.5 0.84 9.0 0.3 2.4 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 KEG06805.1 - 0.083 12.1 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA PF00004.24 KEG06805.1 - 0.095 12.8 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KEG06805.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain KaiC PF06745.8 KEG06805.1 - 0.16 11.0 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 KaiC DUF258 PF03193.11 KEG06805.1 - 0.17 11.0 0.1 1.1 8.3 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 KEG06805.1 - 0.25 11.6 0.1 0.25 11.6 0.1 1.9 2 1 0 2 2 1 0 AAA domain MA3 PF02847.12 KEG06806.1 - 2.1e-12 46.7 0.4 4.3e-12 45.7 0.2 1.5 1 0 0 1 1 1 1 MA3 domain DUF3144 PF11342.3 KEG06806.1 - 0.022 14.7 0.7 2.1 8.4 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3144) Ycf1 PF05758.7 KEG06806.1 - 2.4 5.7 7.3 2.9 5.4 5.0 1.1 1 0 0 1 1 1 0 Ycf1 BNIP2 PF12496.3 KEG06806.1 - 3.2 7.9 7.1 5.9 7.0 4.9 1.4 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 TRM13 PF05206.9 KEG06806.1 - 6.7 5.8 11.7 1.7 7.8 3.5 2.3 1 1 1 2 2 2 0 Methyltransferase TRM13 Kinesin PF00225.18 KEG06807.1 - 2.1e-26 92.4 6.6 5.3e-23 81.2 0.0 3.5 3 1 1 4 4 4 2 Kinesin motor domain Mucin PF01456.12 KEG06809.1 - 1e-10 41.5 12.0 1.3e-10 41.1 8.3 1.1 1 0 0 1 1 1 1 Mucin-like glycoprotein Pex14_N PF04695.8 KEG06809.1 - 0.7 9.9 4.5 0.87 9.6 3.1 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Mito_fiss_reg PF05308.6 KEG06809.1 - 2.4 7.4 11.4 3.3 6.9 7.9 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Totivirus_coat PF05518.6 KEG06809.1 - 5.5 4.6 9.2 5.7 4.6 6.4 1.1 1 0 0 1 1 1 0 Totivirus coat protein Peptidase_M8 PF01457.11 KEG06810.1 - 1.7e-42 145.4 0.5 1.9e-42 145.3 0.3 1.0 1 0 0 1 1 1 1 Leishmanolysin DUF1025 PF06262.6 KEG06810.1 - 0.14 12.0 0.1 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 Possibl zinc metallo-peptidase Choline_kinase PF01633.15 KEG06812.1 - 2.3e-22 79.6 0.2 4.9e-22 78.5 0.1 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 KEG06812.1 - 6e-11 42.5 0.1 3.1e-10 40.1 0.1 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KEG06812.1 - 0.00069 18.8 0.6 0.0011 18.1 0.4 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase PF00069.20 KEG06812.1 - 0.1 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain WD40 PF00400.27 KEG06815.1 - 2.4e-83 271.3 19.7 1.2e-10 40.7 0.0 8.1 8 0 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 KEG06815.1 - 6.7e-09 34.4 13.7 0.25 9.4 0.5 6.4 1 1 5 6 6 6 5 Nucleoporin Nup120/160 CEP19 PF14933.1 KEG06815.1 - 0.012 15.9 0.0 0.018 15.3 0.0 1.2 1 0 0 1 1 1 0 CEP19-like protein DUF4189 PF13827.1 KEG06815.1 - 0.64 10.2 6.5 0.12 12.6 0.8 2.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4189) Mito_carr PF00153.22 KEG06816.1 - 1.4e-68 226.6 5.5 1.1e-25 89.0 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF4257 PF14074.1 KEG06816.1 - 0.0014 18.2 0.0 0.4 10.3 0.1 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF4257) PPR PF01535.15 KEG06816.1 - 0.0025 17.6 0.1 4.9 7.3 0.0 3.0 2 0 0 2 2 2 2 PPR repeat polyprenyl_synt PF00348.12 KEG06817.1 - 1.1e-41 142.4 0.0 1.6e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase CrtC PF07143.6 KEG06817.1 - 2.7e-30 105.7 0.1 3.1e-29 102.2 0.1 2.1 1 1 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) zf-CCCH PF00642.19 KEG06818.1 - 8.4e-07 28.5 1.9 2.4e-06 27.0 1.3 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) His_Phos_1 PF00300.17 KEG06820.1 - 2.3e-30 105.7 0.0 5.2e-30 104.6 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) 6PF2K PF01591.13 KEG06820.1 - 2.1e-19 69.5 4.1 2.4e-12 46.3 0.0 3.5 2 1 1 3 3 3 3 6-phosphofructo-2-kinase AAA_33 PF13671.1 KEG06820.1 - 0.0011 18.9 0.0 0.0072 16.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KEG06820.1 - 0.01 16.6 0.0 0.049 14.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain UBN2_2 PF14227.1 KEG06820.1 - 0.13 11.8 0.1 13 5.3 0.0 2.8 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type TMEM154 PF15102.1 KEG06821.1 - 0.03 14.0 0.0 0.036 13.7 0.0 1.1 1 0 0 1 1 1 0 TMEM154 protein family DUF4636 PF15468.1 KEG06821.1 - 0.058 12.8 0.0 0.067 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) DUF4124 PF13511.1 KEG06821.1 - 0.64 10.1 7.0 6.5 6.8 4.8 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4124) Trp_oprn_chp PF09534.5 KEG06821.1 - 4.1 6.9 8.5 0.99 8.9 0.3 2.0 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Mucin PF01456.12 KEG06826.1 - 1.8e-09 37.5 48.5 0.00014 21.6 9.5 3.2 2 1 0 2 2 2 2 Mucin-like glycoprotein XRCC4 PF06632.7 KEG06826.1 - 0.37 9.5 4.5 0.59 8.9 3.1 1.3 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Mucin PF01456.12 KEG06827.1 - 0.068 12.9 54.3 0.098 12.4 26.7 3.3 1 1 1 2 2 2 0 Mucin-like glycoprotein ATG16 PF08614.6 KEG06828.1 - 0.0092 15.8 19.0 0.015 15.1 13.2 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) ERM PF00769.14 KEG06828.1 - 0.02 14.4 36.7 0.07 12.6 23.5 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family GAS PF13851.1 KEG06828.1 - 0.14 11.3 29.6 0.19 10.9 7.7 2.7 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding ApoLp-III PF07464.6 KEG06828.1 - 0.2 11.7 22.9 0.029 14.3 5.1 2.9 1 1 2 3 3 3 0 Apolipophorin-III precursor (apoLp-III) DUF342 PF03961.8 KEG06828.1 - 0.65 8.3 10.4 0.86 7.9 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Nnf1 PF03980.9 KEG06828.1 - 1.5 8.8 25.3 2.7 8.0 2.4 3.6 1 1 1 2 2 2 0 Nnf1 Peptidase_A3 PF02160.10 KEG06828.1 - 1.6 8.3 6.3 0.63 9.6 0.1 2.0 1 1 1 2 2 2 0 Cauliflower mosaic virus peptidase (A3) PorB PF11565.3 KEG06828.1 - 1.7 8.9 10.8 0.34 11.1 2.1 2.4 1 1 1 2 2 2 0 Alpha helical Porin B DUF641 PF04859.7 KEG06828.1 - 2.2 8.0 18.5 0.68 9.6 6.6 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) ADIP PF11559.3 KEG06828.1 - 3.9 7.3 24.8 19 5.1 17.2 2.0 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding TMCO5 PF14992.1 KEG06828.1 - 8.4 5.4 22.9 4.9 6.1 3.4 2.0 1 1 1 2 2 2 0 TMCO5 family IncA PF04156.9 KEG06829.1 - 0.00017 21.2 46.7 0.12 11.9 13.2 3.7 1 1 2 3 3 3 2 IncA protein AAA_13 PF13166.1 KEG06829.1 - 0.0012 17.4 11.9 0.0012 17.4 8.2 2.1 1 1 1 2 2 2 2 AAA domain Reo_sigmaC PF04582.7 KEG06829.1 - 0.0028 16.9 7.4 0.31 10.1 0.1 3.0 1 1 2 3 3 3 2 Reovirus sigma C capsid protein Filament PF00038.16 KEG06829.1 - 0.07 12.5 36.5 1.8 7.9 7.5 3.1 1 1 1 2 2 2 0 Intermediate filament protein HrpB7 PF09486.5 KEG06829.1 - 0.071 13.0 33.6 0.044 13.7 0.9 4.1 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) HrpA_pilin PF09589.5 KEG06829.1 - 0.083 13.3 3.4 0.078 13.4 0.4 2.2 1 1 1 2 2 2 0 HrpA pilus formation protein DUF4200 PF13863.1 KEG06829.1 - 0.24 11.3 46.1 0.47 10.3 6.5 4.2 1 1 2 4 4 4 0 Domain of unknown function (DUF4200) Tropomyosin PF00261.15 KEG06829.1 - 0.24 10.4 50.2 4.3 6.3 3.6 2.5 1 1 1 2 2 2 0 Tropomyosin Streptin-Immun PF11083.3 KEG06829.1 - 0.25 11.3 0.1 0.25 11.3 0.1 4.3 1 1 2 4 4 4 0 Lantibiotic streptin immunity protein AAA_27 PF13514.1 KEG06829.1 - 0.29 8.7 41.6 6.4 4.3 17.7 1.9 1 1 1 2 2 2 0 AAA domain V_ATPase_I PF01496.14 KEG06829.1 - 0.37 8.5 18.4 1.4 6.7 9.6 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Spc7 PF08317.6 KEG06829.1 - 0.48 9.0 31.6 1.2 7.7 9.4 2.9 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF3584 PF12128.3 KEG06829.1 - 0.64 7.2 39.0 2.1 5.5 27.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Fib_alpha PF08702.5 KEG06829.1 - 0.77 9.8 14.6 7.9 6.5 1.1 3.2 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family GAS PF13851.1 KEG06829.1 - 3 6.9 30.9 13 4.8 0.7 3.4 1 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding AbiH PF14253.1 KEG06829.1 - 3.7 7.0 11.3 6.4 6.3 0.2 2.7 1 1 1 2 2 2 0 Bacteriophage abortive infection AbiH Baculo_PEP_C PF04513.7 KEG06829.1 - 3.7 7.3 10.6 5 6.9 0.1 3.7 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Seryl_tRNA_N PF02403.17 KEG06829.1 - 3.9 7.5 34.0 1.2 9.1 6.0 4.3 1 1 3 4 4 4 0 Seryl-tRNA synthetase N-terminal domain ATG16 PF08614.6 KEG06829.1 - 4.3 7.1 34.5 0.27 11.0 7.7 3.5 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF948 PF06103.6 KEG06829.1 - 4.4 7.2 6.1 12 5.8 0.1 3.4 3 1 2 5 5 5 0 Bacterial protein of unknown function (DUF948) Rgp1 PF08737.5 KEG06829.1 - 6.5 5.7 12.1 0.89 8.5 4.5 1.9 1 1 1 2 2 2 0 Rgp1 COG2 PF06148.6 KEG06829.1 - 7.8 6.3 25.4 4.5 7.1 1.0 4.2 1 1 3 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Pkinase PF00069.20 KEG06830.1 - 6.7e-29 100.8 0.0 9.7e-29 100.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG06830.1 - 1.2e-10 40.9 0.0 1.9e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KEG06830.1 - 0.02 13.9 0.0 0.037 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEG06830.1 - 0.13 11.9 0.1 0.4 10.3 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family RRM_1 PF00076.17 KEG06831.1 - 5.5e-30 102.8 0.0 4.8e-17 61.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG06831.1 - 1.1e-26 92.5 0.0 3.2e-14 52.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG06831.1 - 2.1e-15 56.2 0.0 4.5e-12 45.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 KEG06832.1 - 8.2e-63 211.9 0.0 2.9e-62 210.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG06832.1 - 5.5e-37 127.2 0.0 2.9e-25 88.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KEG06832.1 - 1.8e-05 23.8 0.1 0.0082 15.1 0.0 2.7 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.9 KEG06832.1 - 0.0015 17.6 0.0 0.003 16.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEG06832.1 - 0.1 12.2 4.4 0.24 11.0 3.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_M8 PF01457.11 KEG06833.1 - 9.2e-107 357.5 7.0 2.2e-59 201.1 2.4 2.2 2 0 0 2 2 2 2 Leishmanolysin Reprolysin_5 PF13688.1 KEG06833.1 - 0.005 16.7 0.1 0.005 16.7 0.1 2.4 2 0 0 2 2 2 1 Metallo-peptidase family M12 DUF1388 PF07142.7 KEG06834.1 - 0.21 11.3 0.2 0.21 11.3 0.1 2.8 3 1 0 3 3 3 0 Repeat of unknown function (DUF1388) Metallothi_Euk2 PF12809.2 KEG06834.1 - 3.1 8.2 5.9 1.1 9.6 0.1 2.4 2 1 0 2 2 2 0 Eukaryotic metallothionein CMV_1a PF12467.3 KEG06836.1 - 0.36 11.1 8.7 0.53 10.6 1.1 2.3 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family HisKA_3 PF07730.8 KEG06836.1 - 1.3 9.4 15.0 5.8 7.3 1.2 4.3 2 1 2 4 4 4 0 Histidine kinase Mucin PF01456.12 KEG06837.1 - 1e-11 44.7 7.8 1e-11 44.7 5.4 4.2 1 1 2 3 3 3 1 Mucin-like glycoprotein Mit_KHE1 PF10173.4 KEG06837.1 - 1.1 9.1 13.5 0.86 9.4 1.0 2.5 2 1 0 2 2 2 0 Mitochondrial K+-H+ exchange-related Sec20 PF03908.8 KEG06837.1 - 2.5 7.8 5.4 1.3 8.7 0.3 2.7 2 1 1 3 3 3 0 Sec20 Mucin PF01456.12 KEG06838.1 - 1.5e-09 37.7 43.2 4e-06 26.6 9.9 2.9 2 1 0 2 2 2 2 Mucin-like glycoprotein JAB PF01398.16 KEG06839.1 - 1e-08 34.8 1.0 2.6e-08 33.5 0.0 2.2 2 1 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KEG06839.1 - 0.0006 19.8 0.0 0.0013 18.7 0.0 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function BT1 PF03092.11 KEG06840.1 - 1e-159 531.9 5.8 1.2e-159 531.6 4.0 1.0 1 0 0 1 1 1 1 BT1 family DUF2453 PF10507.4 KEG06841.1 - 9e-40 134.9 2.5 9e-40 134.9 1.7 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2453) Dpy-30 PF05186.8 KEG06842.1 - 4.5e-08 32.4 0.2 6.9e-08 31.8 0.1 1.3 1 0 0 1 1 1 1 Dpy-30 motif YqhG PF11079.3 KEG06842.1 - 0.015 14.0 1.7 0.022 13.5 1.1 1.2 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function FIVAR PF07554.8 KEG06842.1 - 0.045 13.9 1.9 0.48 10.7 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised Sugar-binding Domain Cpn60_TCP1 PF00118.19 KEG06843.1 - 5.3e-137 457.3 8.1 6e-137 457.1 5.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cation_efflux PF01545.16 KEG06844.1 - 1.3e-51 175.4 22.2 5.6e-51 173.3 9.2 2.3 2 1 0 2 2 2 2 Cation efflux family Androgen_recep PF02166.11 KEG06846.1 - 0.0045 15.9 3.1 0.017 14.0 0.0 2.2 2 0 0 2 2 2 1 Androgen receptor Phage_GP20 PF06810.6 KEG06846.1 - 0.012 15.0 1.8 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 Seryl_tRNA_N PF02403.17 KEG06846.1 - 0.012 15.5 9.4 0.11 12.4 1.9 2.8 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Med9 PF07544.8 KEG06846.1 - 0.038 13.7 5.5 1.3 8.8 0.3 3.6 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 CENP-F_leu_zip PF10473.4 KEG06846.1 - 0.04 13.7 16.2 0.08 12.8 0.4 3.4 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HTH_23 PF13384.1 KEG06846.1 - 0.052 13.2 1.6 0.15 11.7 0.2 2.4 2 0 0 2 2 2 0 Homeodomain-like domain TrmB PF01978.14 KEG06846.1 - 0.19 11.4 1.9 9.4 6.0 0.2 3.1 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB GAS PF13851.1 KEG06846.1 - 0.26 10.4 9.9 1.9 7.6 3.0 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.14 KEG06846.1 - 0.55 8.0 3.8 0.68 7.7 2.1 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DegT_DnrJ_EryC1 PF01041.12 KEG06846.1 - 0.97 8.3 8.4 1.1 8.2 1.3 2.1 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Atg14 PF10186.4 KEG06846.1 - 1 8.2 10.8 0.87 8.4 0.8 2.3 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1515 PF07439.6 KEG06846.1 - 1.3 8.8 4.3 0.7 9.7 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Spc7 PF08317.6 KEG06846.1 - 1.5 7.4 9.9 80 1.7 6.5 2.1 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF2605 PF10792.4 KEG06846.1 - 1.6 8.4 5.7 0.26 10.9 0.7 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2605) Mei5 PF10376.4 KEG06846.1 - 6.6 6.1 8.3 5.5 6.4 3.1 2.2 2 0 0 2 2 2 0 Double-strand recombination repair protein DivIVA PF05103.8 KEG06846.1 - 6.9 6.7 13.0 2.5 8.1 3.5 2.4 2 0 0 2 2 2 0 DivIVA protein Pkinase PF00069.20 KEG06847.1 - 6e-62 209.1 0.0 8.5e-62 208.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG06847.1 - 1.8e-25 89.5 0.0 2.5e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG06847.1 - 0.00012 21.1 0.0 0.00029 19.8 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KEG06847.1 - 0.087 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FAM60A PF15396.1 KEG06848.1 - 1.2 8.8 4.3 1.7 8.3 3.0 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF383 PF04063.9 KEG06851.1 - 6.1e-08 32.4 0.0 1.9e-05 24.3 0.0 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF383) HEAT_2 PF13646.1 KEG06851.1 - 0.0003 20.9 0.7 1.8 8.8 0.0 4.2 4 1 0 4 4 4 2 HEAT repeats Arm PF00514.18 KEG06851.1 - 0.023 14.4 2.4 41 4.1 0.0 4.9 5 1 0 5 5 5 0 Armadillo/beta-catenin-like repeat HEAT PF02985.17 KEG06851.1 - 0.19 11.8 2.3 10 6.4 0.0 4.0 5 0 0 5 5 5 0 HEAT repeat Toxin_25 PF08095.6 KEG06851.1 - 3.8 7.3 9.8 9 6.1 0.6 2.7 2 0 0 2 2 2 0 Hefutoxin family DUF1935 PF09149.5 KEG06853.1 - 8e-39 131.8 0.2 2.6e-27 94.8 0.0 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF1935) DUF3806 PF12713.2 KEG06853.1 - 0.052 12.9 0.1 4.1 6.9 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3806) DUF1767 PF08585.7 KEG06854.1 - 0.00035 20.7 0.0 0.001 19.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) Steroid_dh PF02544.11 KEG06855.1 - 5.5e-23 81.4 0.3 9.9e-23 80.5 0.2 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 KEG06855.1 - 0.0041 16.4 0.1 0.0061 15.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) E1-E2_ATPase PF00122.15 KEG06856.1 - 7.4e-52 175.6 0.4 7.4e-52 175.6 0.3 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KEG06856.1 - 6e-39 133.4 5.9 1.4e-38 132.2 4.1 1.7 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KEG06856.1 - 3.8e-22 79.7 0.0 5.3e-21 76.0 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KEG06856.1 - 2.5e-15 55.7 0.0 5.2e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KEG06856.1 - 2.4e-11 44.1 0.0 8.7e-11 42.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEG06856.1 - 4.7e-11 42.4 0.0 1.2e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KEG06856.1 - 4.3e-06 26.4 0.1 0.0004 20.0 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2757 PF10955.3 KEG06857.1 - 0.014 15.6 1.0 0.032 14.4 0.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2757) Jnk-SapK_ap_N PF09744.4 KEG06857.1 - 0.016 15.2 15.0 0.016 15.2 10.4 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 L27_N PF09060.5 KEG06857.1 - 0.038 13.8 0.3 0.13 12.0 0.2 1.9 1 0 0 1 1 1 0 L27_N Reo_sigmaC PF04582.7 KEG06857.1 - 0.14 11.3 5.1 0.08 12.1 1.6 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Pkip-1 PF06878.6 KEG06857.1 - 1.5 8.6 14.2 0.11 12.4 1.8 2.4 1 1 0 2 2 2 0 Pkip-1 protein NPV_P10 PF05531.7 KEG06857.1 - 1.6 9.0 12.9 1.5e+02 2.7 6.8 3.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Wzz PF02706.10 KEG06857.1 - 1.7 8.4 8.4 10 5.8 5.8 2.1 1 1 0 1 1 1 0 Chain length determinant protein DUF241 PF03087.9 KEG06857.1 - 2.4 7.5 19.2 5.1 6.5 13.3 1.5 1 1 0 1 1 1 0 Arabidopsis protein of unknown function LMBR1 PF04791.11 KEG06857.1 - 2.7 6.4 7.7 3.4 6.1 5.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Mucin PF01456.12 KEG06863.1 - 7.9e-05 22.4 0.4 7.9e-05 22.4 0.3 3.4 3 1 0 3 3 3 1 Mucin-like glycoprotein Trypan_PARP PF05887.6 KEG06863.1 - 0.015 15.0 6.2 0.015 15.0 4.3 3.1 3 1 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) Pkinase PF00069.20 KEG06865.1 - 1.1e-36 126.3 0.0 6.2e-31 107.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEG06865.1 - 3.8e-20 72.0 0.0 5.4e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEG06865.1 - 6.4e-07 29.3 0.0 1.2e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 KEG06866.1 - 6.4e-48 163.1 0.0 1.2e-47 162.2 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG06866.1 - 1.5e-27 96.3 0.0 8.6e-27 93.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.3 KEG06866.1 - 0.00051 19.3 0.2 0.0027 16.9 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3543) Kdo PF06293.9 KEG06866.1 - 0.0015 17.6 0.0 0.0027 16.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEG06866.1 - 0.0029 17.3 0.2 0.0091 15.7 0.1 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family FH2 PF02181.18 KEG06868.1 - 4.1 6.1 22.8 0.061 12.2 0.9 3.7 2 2 2 4 4 4 0 Formin Homology 2 Domain MCPsignal PF00015.16 KEG06868.1 - 4.1 6.8 37.0 0.066 12.7 8.0 3.1 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain ALMT PF11744.3 KEG06868.1 - 7.3 5.1 13.9 0.39 9.3 2.5 2.2 2 0 0 2 2 2 0 Aluminium activated malate transporter PP2C PF00481.16 KEG06871.1 - 6.9e-56 189.4 0.0 9.8e-56 188.9 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KEG06871.1 - 0.00016 21.1 0.1 0.00067 19.1 0.0 2.1 3 0 0 3 3 3 1 Protein phosphatase 2C FYVE PF01363.16 KEG06872.1 - 1.4e-13 50.4 13.6 3.8e-13 49.1 9.0 2.1 1 1 0 1 1 1 1 FYVE zinc finger zf-DHHC PF01529.15 KEG06872.1 - 1 8.7 9.2 0.32 10.3 0.0 2.5 3 0 0 3 3 3 0 DHHC palmitoyltransferase ACC_central PF08326.7 KEG06873.1 - 4.8e-64 216.7 0.0 3.3e-57 194.1 0.0 2.3 2 0 0 2 2 2 2 Acetyl-CoA carboxylase, central region CPSase_L_D2 PF02786.12 KEG06873.1 - 1.3e-48 165.0 0.1 2.8e-48 163.9 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 KEG06873.1 - 7e-25 87.2 0.0 1.5e-24 86.1 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KEG06873.1 - 7.5e-21 74.1 0.0 1.5e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 KEG06873.1 - 6.4e-14 52.1 0.0 1.3e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KEG06873.1 - 6.3e-13 48.1 0.0 9.7e-08 31.1 0.1 2.7 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 KEG06873.1 - 7.3e-10 38.3 0.1 2e-09 36.9 0.1 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 KEG06873.1 - 9.7e-08 31.6 0.0 1.8e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KEG06873.1 - 0.00023 20.5 0.3 0.00047 19.5 0.2 1.5 1 0 0 1 1 1 1 ATP-grasp domain Mpp10 PF04006.7 KEG06874.1 - 0.023 13.0 6.1 0.023 13.0 4.3 1.0 1 0 0 1 1 1 0 Mpp10 protein Myc_N PF01056.13 KEG06874.1 - 0.07 12.2 3.4 0.068 12.3 2.3 1.0 1 0 0 1 1 1 0 Myc amino-terminal region Cwf_Cwc_15 PF04889.7 KEG06874.1 - 0.14 11.8 4.9 0.14 11.8 3.4 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nucleoplasmin PF03066.10 KEG06874.1 - 0.2 11.1 5.7 0.26 10.8 4.0 1.2 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 KEG06874.1 - 0.27 10.8 4.7 0.28 10.7 3.2 1.0 1 0 0 1 1 1 0 Sigma-70, non-essential region PBP1_TM PF14812.1 KEG06874.1 - 0.97 9.7 5.3 1.3 9.3 3.7 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.9 KEG06874.1 - 1.4 6.8 4.3 1.4 6.8 3.0 1.0 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 KEG06874.1 - 1.6 7.9 6.3 1.7 7.8 4.4 1.0 1 0 0 1 1 1 0 NOA36 protein DUF2890 PF11081.3 KEG06874.1 - 1.7 8.6 5.1 1.7 8.6 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) CENP-B_dimeris PF09026.5 KEG06874.1 - 1.8 8.8 8.3 2.1 8.6 5.8 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain WD40 PF00400.27 KEG06875.1 - 1.2e-11 44.0 3.1 0.0025 17.6 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat HEAT_2 PF13646.1 KEG06875.1 - 0.017 15.3 1.2 0.027 14.7 0.2 1.9 2 0 0 2 2 2 0 HEAT repeats Mcm10 PF09332.6 KEG06879.1 - 0.13 11.5 0.9 0.17 11.2 0.6 1.1 1 0 0 1 1 1 0 Mcm10 replication factor DUF326 PF03860.11 KEG06880.1 - 0.11 12.3 4.6 0.23 11.3 3.2 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF326) APC_CDC26 PF10471.4 KEG06883.1 - 0.043 14.5 0.1 0.066 13.9 0.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 DUF1556 PF07590.6 KEG06883.1 - 1 9.6 6.3 0.8 9.9 2.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1556) PX PF00787.19 KEG06885.1 - 0.00033 20.4 0.0 0.00035 20.3 0.0 1.1 1 0 0 1 1 1 1 PX domain Pilus_PilP PF11356.3 KEG06886.1 - 1.2 9.4 3.8 2.2 8.5 2.6 1.6 1 1 0 1 1 1 0 Type IV pilus biogenesis Hist_deacetyl PF00850.14 KEG06888.1 - 0.03 13.6 0.9 0.053 12.8 0.6 1.3 1 0 0 1 1 1 0 Histone deacetylase domain tRNA-synt_2 PF00152.15 KEG06890.1 - 1.6e-89 299.9 0.1 2.1e-89 299.6 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KEG06890.1 - 3.4e-12 46.0 0.1 6.5e-12 45.1 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KEG06890.1 - 2e-07 30.4 0.0 0.0015 17.7 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) Seryl_tRNA_N PF02403.17 KEG06890.1 - 0.0076 16.2 1.3 0.0076 16.2 0.9 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain CP12 PF02672.10 KEG06890.1 - 0.13 12.7 0.6 0.24 11.8 0.4 1.4 1 0 0 1 1 1 0 CP12 domain M20_dimer PF07687.9 KEG06891.1 - 1.8e-18 66.3 0.0 2.7e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 KEG06891.1 - 4.2e-12 45.9 2.3 6.7e-12 45.2 1.6 1.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 zf-U1 PF06220.7 KEG06892.1 - 0.062 12.8 0.6 2.8 7.5 0.1 2.2 2 0 0 2 2 2 0 U1 zinc finger Mob_Pre PF01076.14 KEG06892.1 - 0.15 11.7 5.1 0.18 11.4 3.6 1.1 1 0 0 1 1 1 0 Plasmid recombination enzyme Mnd1 PF03962.10 KEG06892.1 - 1 9.0 4.2 1.5 8.4 2.9 1.4 1 1 0 1 1 1 0 Mnd1 family PA26 PF04636.8 KEG06892.1 - 1.7 7.2 4.5 2 7.0 3.1 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Seryl_tRNA_N PF02403.17 KEG06892.1 - 2.1 8.3 8.5 0.66 10.0 3.1 1.8 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DASH_Spc19 PF08287.6 KEG06892.1 - 4.7 6.8 7.3 2 7.9 0.8 1.5 1 1 1 2 2 2 0 Spc19 APC_CDC26 PF10471.4 KEG06892.1 - 6.1 7.6 13.1 0.36 11.5 2.2 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex APC subunit 1 AAA_27 PF13514.1 KEG06893.1 - 2.2 5.8 77.3 0.045 11.4 41.3 2.1 2 0 0 2 2 2 0 AAA domain LPP PF04728.8 KEG06893.1 - 4 7.2 9.5 0.58 9.9 2.6 2.6 3 0 0 3 3 3 0 Lipoprotein leucine-zipper Reo_sigmaC PF04582.7 KEG06893.1 - 4.5 6.3 6.8 54 2.8 0.7 3.9 2 1 2 4 4 4 0 Reovirus sigma C capsid protein DUF3275 PF11679.3 KEG06894.1 - 0.089 12.4 0.6 0.54 9.8 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3275) CTD_bind PF04818.8 KEG06894.1 - 0.11 12.8 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase II-binding domain. Glyco_hydro_31 PF01055.21 KEG06895.1 - 5.5e-15 55.1 0.1 2.9e-12 46.1 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 31 Phytochelatin PF05023.9 KEG06899.1 - 2.2e-10 39.8 0.1 0.00021 20.3 0.0 4.0 5 0 0 5 5 5 2 Phytochelatin synthase Nucleoside_tran PF01733.13 KEG06901.1 - 1.4e-30 106.5 4.4 1.4e-30 106.5 3.1 1.6 2 0 0 2 2 2 1 Nucleoside transporter TGT PF01702.13 KEG06901.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Queuine tRNA-ribosyltransferase DUF2881 PF11087.3 KEG06902.1 - 0.11 12.0 0.5 0.16 11.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2881) Claudin_2 PF13903.1 KEG06904.1 - 0.016 14.8 8.6 0.032 13.9 6.0 1.7 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 KEG06904.1 - 0.045 13.4 7.5 0.13 11.9 5.2 1.8 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family DUF4149 PF13664.1 KEG06904.1 - 2.6 8.1 7.0 0.51 10.4 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) DUF706 PF05153.10 KEG06912.1 - 4.4e-05 22.9 0.9 0.12 11.6 0.1 2.3 2 0 0 2 2 2 2 Family of unknown function (DUF706) Toprim PF01751.17 KEG06912.1 - 0.00013 21.9 0.4 0.05 13.5 0.0 2.7 2 0 0 2 2 2 2 Toprim domain B9-C2 PF07162.6 KEG06913.1 - 7.4e-24 84.4 0.0 1.2e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Guanylin PF02058.10 KEG06914.1 - 0.06 13.4 0.7 0.63 10.1 0.1 2.1 1 1 0 2 2 2 0 Guanylin precursor ARGLU PF15346.1 KEG06914.1 - 0.2 11.4 11.2 0.25 11.1 7.8 1.1 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 Adeno_VII PF03228.9 KEG06914.1 - 7.6 7.1 8.3 11 6.6 5.8 1.3 1 0 0 1 1 1 0 Adenoviral core protein VII DUF4512 PF14975.1 KEG06915.1 - 0.015 16.1 0.0 0.026 15.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) DUF4482 PF14818.1 KEG06915.1 - 0.077 13.6 0.2 0.14 12.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) zf-RING_2 PF13639.1 KEG06916.1 - 2.8e-14 52.6 4.6 4.4e-14 52.0 3.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KEG06916.1 - 2.2e-10 40.5 5.8 3.4e-10 39.8 4.0 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KEG06916.1 - 1.9e-07 31.0 4.6 3.9e-07 29.9 3.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEG06916.1 - 3e-07 29.9 5.0 5.3e-07 29.1 3.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEG06916.1 - 5e-06 26.0 5.2 5e-06 26.0 3.6 1.6 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEG06916.1 - 1.9e-05 24.3 6.8 3.2e-05 23.5 4.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KEG06916.1 - 3.5e-05 23.5 3.5 5.7e-05 22.8 2.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 KEG06916.1 - 0.0037 17.1 6.5 0.015 15.2 4.5 1.9 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_6 PF14835.1 KEG06916.1 - 0.03 14.0 0.6 0.079 12.7 0.1 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 KEG06916.1 - 0.089 12.5 3.3 0.13 11.9 0.5 2.4 1 1 1 2 2 2 0 RING-type zinc-finger Papo_T_antigen PF02380.10 KEG06916.1 - 0.1 12.5 2.7 0.16 11.9 1.9 1.2 1 0 0 1 1 1 0 T-antigen specific domain zf-Nse PF11789.3 KEG06916.1 - 0.17 11.4 2.0 0.32 10.5 1.4 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 KEG06916.1 - 0.52 9.9 6.8 0.7 9.5 3.8 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 KEG06916.1 - 0.88 9.6 7.1 1.7 8.7 5.0 1.5 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.24 KEG06916.1 - 1.2 8.9 9.2 2.6 7.7 6.3 1.6 1 1 0 1 1 1 0 PHD-finger Rad50_zn_hook PF04423.9 KEG06916.1 - 1.6 8.2 5.4 4 6.9 0.2 2.7 3 0 0 3 3 3 0 Rad50 zinc hook motif PilM PF07419.7 KEG06917.1 - 0.076 12.5 1.2 1 8.8 0.4 2.2 1 1 1 2 2 2 0 PilM Med22 PF06179.7 KEG06918.1 - 0.73 9.8 9.9 0.14 12.1 3.3 2.4 2 0 0 2 2 2 0 Surfeit locus protein 5 subunit 22 of Mediator complex DUF3153 PF11353.3 KEG06918.1 - 5 6.5 7.0 1.6 8.1 0.2 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3153) Cob_adeno_trans PF01923.13 KEG06919.1 - 0.1 12.3 2.0 0.17 11.7 1.4 1.3 1 0 0 1 1 1 0 Cobalamin adenosyltransferase DUF2247 PF10004.4 KEG06919.1 - 0.99 9.0 4.2 0.33 10.6 0.5 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2247) FliJ PF02050.11 KEG06919.1 - 1.3 9.0 18.7 0.86 9.6 4.5 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein DUF812 PF05667.6 KEG06919.1 - 3.7 5.9 17.6 5.1 5.4 12.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) TrbL PF04610.9 KEG06921.1 - 0.038 13.7 0.3 0.055 13.1 0.2 1.2 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein EphA2_TM PF14575.1 KEG06921.1 - 0.078 13.3 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain P12 PF12669.2 KEG06921.1 - 0.084 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Virus attachment protein p12 family DUF1191 PF06697.7 KEG06921.1 - 0.099 11.4 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) IncA PF04156.9 KEG06921.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 IncA protein ICA69 PF04629.9 KEG06924.1 - 0.1 12.5 0.0 18 5.1 0.0 2.2 1 1 1 2 2 2 0 Islet cell autoantigen ICA69, C-terminal domain LRR_8 PF13855.1 KEG06925.1 - 9.5e-06 25.2 0.5 0.001 18.7 0.0 3.3 1 1 2 3 3 3 1 Leucine rich repeat LRR_1 PF00560.28 KEG06925.1 - 5e-05 22.7 1.5 0.66 10.2 0.0 4.2 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.1 KEG06925.1 - 0.0056 16.6 6.3 0.11 12.6 0.2 4.6 5 1 0 5 5 5 1 Leucine Rich repeat LRR_4 PF12799.2 KEG06925.1 - 0.0087 15.6 3.0 0.13 11.8 0.1 4.2 3 2 2 5 5 5 2 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.7 KEG06925.1 - 0.019 14.9 2.5 0.022 14.7 0.1 2.4 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain Nucleoside_tran PF01733.13 KEG06925.1 - 0.044 12.9 0.1 0.063 12.4 0.0 1.2 1 0 0 1 1 1 0 Nucleoside transporter LRR_7 PF13504.1 KEG06925.1 - 0.15 12.3 1.3 10 6.8 0.0 3.4 3 0 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.28 KEG06927.1 - 2.9e-06 26.5 0.0 0.77 10.0 0.0 3.8 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_8 PF13855.1 KEG06927.1 - 1.7e-05 24.4 0.0 0.014 15.1 0.0 2.8 2 1 1 3 3 3 2 Leucine rich repeat LRR_6 PF13516.1 KEG06927.1 - 0.00021 21.0 0.2 1.3 9.3 0.0 4.0 3 1 1 4 4 4 1 Leucine Rich repeat LRR_4 PF12799.2 KEG06927.1 - 0.00057 19.4 0.0 0.051 13.2 0.0 3.1 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) zf-C2HC_2 PF13913.1 KEG06930.1 - 5.8e-08 32.2 0.2 9.3e-08 31.5 0.1 1.3 1 0 0 1 1 1 1 zinc-finger of a C2HC-type WD40 PF00400.27 KEG06931.1 - 0.0085 15.9 0.2 7 6.7 0.0 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat PQQ_3 PF13570.1 KEG06931.1 - 0.094 13.0 2.2 1.6 9.1 0.0 3.3 4 0 0 4 4 4 0 PQQ-like domain Methyltransf_23 PF13489.1 KEG06932.1 - 3.1e-07 30.2 0.0 5.6e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEG06932.1 - 3.2e-05 24.4 0.0 7.7e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEG06932.1 - 0.00054 20.2 0.0 0.0028 17.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEG06932.1 - 0.0012 19.2 0.0 0.03 14.7 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEG06932.1 - 0.0024 18.3 0.0 0.38 11.2 0.0 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEG06932.1 - 0.032 13.8 0.0 0.36 10.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain CMAS PF02353.15 KEG06932.1 - 0.15 11.0 0.0 0.35 9.8 0.0 1.5 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase TatD_DNase PF01026.16 KEG06934.1 - 1.1e-23 83.7 0.0 3.1e-23 82.2 0.0 1.7 1 1 0 1 1 1 1 TatD related DNase TPR_2 PF07719.12 KEG06935.1 - 3e-08 32.9 4.9 0.002 17.8 0.1 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEG06935.1 - 4e-08 32.4 0.1 0.0054 16.4 0.0 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEG06935.1 - 7e-08 32.3 5.2 5.5e-06 26.2 1.3 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 KEG06935.1 - 1e-06 28.2 5.1 2.6e-05 23.7 0.9 3.0 2 1 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 KEG06935.1 - 0.0003 20.2 2.4 0.22 11.2 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KEG06935.1 - 0.00062 19.3 0.2 0.091 12.5 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEG06935.1 - 0.001 19.3 1.0 0.0097 16.2 0.2 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEG06935.1 - 0.0044 17.6 2.7 0.0044 17.6 1.9 3.6 4 1 1 5 5 4 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 KEG06935.1 - 0.0056 15.8 0.6 0.019 14.1 0.4 2.0 1 0 0 1 1 1 1 SHNi-TPR TPR_14 PF13428.1 KEG06935.1 - 0.013 16.1 9.4 0.41 11.4 0.0 4.5 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEG06935.1 - 1.3 9.6 3.9 1.7 9.2 0.0 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat Spore_coat_CotO PF14153.1 KEG06935.1 - 1.6 8.1 10.1 0.12 11.8 3.3 1.9 2 0 0 2 2 2 0 Spore coat protein CotO Peripla_BP_6 PF13458.1 KEG06936.1 - 2e-11 43.8 0.0 1e-06 28.3 0.0 2.3 2 0 0 2 2 2 2 Periplasmic binding protein Guanylate_cyc PF00211.15 KEG06936.1 - 0.018 14.3 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain CABS1 PF15367.1 KEG06938.1 - 0.071 11.9 0.3 0.16 10.7 0.2 1.6 1 1 0 1 1 1 0 Calcium-binding and spermatid-specific protein 1 RHSP PF07999.6 KEG06939.1 - 5e-20 71.5 0.0 8.5e-20 70.7 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon hot spot protein RHSP PF07999.6 KEG06940.1 - 3.1e-31 108.4 0.2 3.5e-31 108.2 0.1 1.0 1 0 0 1 1 1 1 Retrotransposon hot spot protein AAA_10 PF12846.2 KEG06940.1 - 0.0031 17.0 0.0 0.0037 16.7 0.0 1.1 1 0 0 1 1 1 1 AAA-like domain NUMOD4 PF07463.6 KEG06940.1 - 0.033 14.0 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 NUMOD4 motif KaiC PF06745.8 KEG06940.1 - 0.066 12.3 0.0 0.087 11.9 0.0 1.3 1 1 0 1 1 1 0 KaiC DUF1214 PF06742.6 KEG06948.1 - 0.0049 17.3 0.2 0.1 13.1 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1214) Thioredoxin_2 PF13098.1 KEG06949.1 - 0.00029 20.9 0.0 0.00054 20.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 KEG06949.1 - 0.13 11.7 0.1 0.13 11.7 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin Methyltransf_11 PF08241.7 KEG06950.1 - 2.6e-10 40.6 0.0 2.5e-05 24.6 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 KEG06950.1 - 2.2e-08 33.9 0.0 3.9e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain WBS_methylT PF12589.3 KEG06950.1 - 9.3e-08 32.4 11.9 9.3e-08 32.4 8.3 2.6 2 2 1 3 3 2 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_25 PF13649.1 KEG06950.1 - 1.7e-06 28.2 0.0 6.8e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEG06950.1 - 2.5e-06 27.1 0.0 0.00014 21.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEG06950.1 - 3.9e-06 27.2 0.0 3.3e-05 24.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEG06950.1 - 4.9e-06 26.5 0.0 8.2e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEG06950.1 - 6.4e-06 26.7 0.0 1e-05 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KEG06950.1 - 0.011 14.8 0.0 0.027 13.5 0.0 1.5 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Nucleoplasmin PF03066.10 KEG06950.1 - 0.026 14.0 0.4 0.026 14.0 0.2 2.6 2 1 0 2 2 1 0 Nucleoplasmin Myc_N PF01056.13 KEG06950.1 - 0.033 13.3 5.5 0.13 11.4 0.0 2.2 2 0 0 2 2 2 0 Myc amino-terminal region PCMT PF01135.14 KEG06950.1 - 0.12 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NOA36 PF06524.7 KEG06950.1 - 0.32 10.2 4.2 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 NOA36 protein Sigma70_ner PF04546.8 KEG06950.1 - 0.63 9.6 10.1 1.4 8.5 0.4 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region SDA1 PF05285.7 KEG06950.1 - 1.4 8.0 12.3 0.6 9.3 1.0 2.1 2 0 0 2 2 2 0 SDA1 CENP-B_dimeris PF09026.5 KEG06950.1 - 1.6 9.0 24.0 0.55 10.5 1.5 3.0 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Retinal PF15449.1 KEG06950.1 - 7.2 4.1 7.9 0.24 9.0 0.4 1.8 2 0 0 2 2 2 0 Retinal protein Mucin PF01456.12 KEG06952.1 - 0.0016 18.2 24.5 0.023 14.4 5.6 3.0 2 2 0 2 2 2 2 Mucin-like glycoprotein ACC_epsilon PF13822.1 KEG06954.1 - 0.017 15.4 0.1 0.06 13.6 0.1 1.9 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit DUF4591 PF15261.1 KEG06955.1 - 3.1e-13 50.1 13.6 4.4e-07 30.2 1.4 2.7 1 1 1 2 2 2 2 Domain of unknown function (DUF4591) DUF2019 PF09450.5 KEG06956.1 - 0.054 13.3 0.1 0.07 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2019) HAMP PF00672.20 KEG06956.1 - 0.082 13.1 0.0 0.17 12.1 0.0 1.7 1 1 1 2 2 2 0 HAMP domain Ribosomal_60s PF00428.14 KEG06957.1 - 5.8e-05 23.4 2.3 5.8e-05 23.4 1.6 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein AIF_C PF14721.1 KEG06957.1 - 0.2 11.9 0.4 0.39 10.9 0.3 1.4 1 1 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term ACC_epsilon PF13822.1 KEG06957.1 - 5 7.5 9.1 3.6 8.0 0.1 2.7 2 1 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit FYVE PF01363.16 KEG06958.1 - 4.4e-20 71.3 4.1 4.4e-20 71.3 2.8 2.6 2 0 0 2 2 2 1 FYVE zinc finger Ank_2 PF12796.2 KEG06961.1 - 4.8e-30 103.7 4.8 1.8e-12 47.4 0.5 4.4 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KEG06961.1 - 2e-21 75.4 17.5 6.9e-10 38.8 0.6 7.0 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.25 KEG06961.1 - 1e-20 72.3 21.8 2.6e-07 30.0 0.2 8.1 7 1 0 7 7 7 4 Ankyrin repeat Ank_3 PF13606.1 KEG06961.1 - 2.8e-19 67.2 12.8 0.00051 20.0 0.0 7.7 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 KEG06961.1 - 2.5e-18 66.0 9.6 3.1e-09 37.0 0.1 5.5 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.25 KEG06962.1 - 2.2e-21 74.5 7.6 0.00013 21.6 0.0 7.3 7 0 0 7 7 7 5 Ankyrin repeat Ank_2 PF12796.2 KEG06962.1 - 1.9e-19 69.8 2.4 6e-08 32.9 0.1 4.9 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KEG06962.1 - 8e-17 59.6 4.2 0.017 15.3 0.0 7.1 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.1 KEG06962.1 - 3.1e-14 52.6 8.5 6.4e-06 26.2 0.2 6.1 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEG06962.1 - 2.8e-12 46.8 1.0 0.00096 19.6 0.0 5.3 5 0 0 5 5 5 2 Ankyrin repeats (many copies) DUF1700 PF08006.6 KEG06963.1 - 1.7 7.9 4.4 2.4 7.4 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) KASH PF10541.4 KEG06963.1 - 7.4 6.5 16.3 2.5e+02 1.5 11.3 2.5 1 1 0 1 1 1 0 Nuclear envelope localisation domain EF-hand_6 PF13405.1 KEG06965.1 - 0.0019 17.8 0.1 0.15 12.0 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 KEG06965.1 - 0.0044 16.2 0.2 0.15 11.4 0.1 3.1 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.1 KEG06965.1 - 0.011 15.8 0.0 0.078 13.1 0.0 2.3 3 0 0 3 3 3 0 EF-hand domain pair IPK PF03770.11 KEG06967.1 - 2.6e-17 63.1 0.0 3.4e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase zf-C2H2_4 PF13894.1 KEG06970.1 - 1.8e-06 27.8 32.2 0.075 13.4 0.2 6.0 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KEG06970.1 - 6.4e-05 23.0 30.8 0.19 12.1 0.2 5.5 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KEG06970.1 - 7.6e-05 22.8 23.1 0.18 12.1 1.0 7.6 7 1 0 7 7 7 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KEG06970.1 - 0.00062 19.8 4.9 3.2 7.9 0.0 4.9 5 0 0 5 5 5 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KEG06970.1 - 0.0051 16.9 10.1 5.5 7.3 0.0 5.2 5 0 0 5 5 5 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KEG06970.1 - 0.049 13.7 13.1 8.1 6.6 0.2 4.9 2 2 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.1 KEG06970.1 - 0.1 12.8 0.1 0.1 12.8 0.1 5.5 5 1 0 5 5 5 0 C2H2-type zinc-finger domain zf-C4pol PF14260.1 KEG06970.1 - 1.1 9.3 5.1 5.6 7.0 0.1 2.7 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta zf-BED PF02892.10 KEG06970.1 - 1.1 9.0 0.0 1.1 9.0 0.0 4.9 5 0 0 5 5 5 0 BED zinc finger zf-ISL3 PF14690.1 KEG06970.1 - 9.5 6.3 15.9 1.2 9.1 0.6 4.4 4 0 0 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Exo_endo_phos_2 PF14529.1 KEG06971.1 - 2.6e-11 43.1 0.0 4.8e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase ZZ PF00569.12 KEG06976.1 - 0.012 15.0 2.1 0.031 13.8 1.4 1.7 1 0 0 1 1 1 0 Zinc finger, ZZ type FYVE PF01363.16 KEG06976.1 - 0.022 14.6 0.4 0.044 13.6 0.3 1.5 1 0 0 1 1 1 0 FYVE zinc finger Prok-RING_2 PF14445.1 KEG06976.1 - 0.055 13.4 0.4 0.11 12.4 0.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 Aa_trans PF01490.13 KEG06977.1 - 7.2e-53 179.5 33.8 9.3e-53 179.1 23.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KEG06977.1 - 7.2e-12 44.8 13.0 7.2e-12 44.8 9.0 2.0 2 1 1 3 3 3 1 Tryptophan/tyrosine permease family AA_permease_2 PF13520.1 KEG06977.1 - 0.00011 20.8 24.3 0.00011 20.8 16.9 2.2 1 1 1 2 2 2 1 Amino acid permease DUF4231 PF14015.1 KEG06977.1 - 2.6 8.0 6.4 6.3 6.8 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) BRF1 PF07741.8 KEG06979.1 - 2.2 8.5 5.5 7.6 6.8 3.8 1.9 1 0 0 1 1 1 0 Brf1-like TBP-binding domain CTD PF12815.2 KEG06980.1 - 0.028 14.8 0.4 0.033 14.6 0.3 1.2 1 0 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 OGFr_N PF04664.8 KEG06984.1 - 4.9e-09 35.8 0.5 0.00014 21.2 0.0 2.4 2 0 0 2 2 2 2 Opioid growth factor receptor (OGFr) conserved region HSP70 PF00012.15 KEG06985.1 - 3.2e-78 263.1 0.1 8.8e-78 261.7 0.0 1.6 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 KEG06985.1 - 2.5e-05 23.0 0.1 0.002 16.8 0.1 2.8 2 1 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 KEG06985.1 - 0.0006 19.6 0.0 3 7.7 0.0 3.6 3 1 0 3 3 3 1 Cell division protein FtsA FGGY_C PF02782.11 KEG06985.1 - 0.01 15.4 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 KEG06985.1 - 0.031 13.0 0.0 3.9 6.1 0.0 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain TFIIA PF03153.8 KEG06986.1 - 1.1 9.0 31.2 2.9 7.7 21.6 1.6 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PriCT_2 PF08707.6 KEG06987.1 - 2e-16 59.5 0.3 4.3e-16 58.5 0.2 1.5 1 0 0 1 1 1 1 Primase C terminal 2 (PriCT-2) MADF_DNA_bdg PF10545.4 KEG06987.1 - 0.024 14.8 0.7 4.1 7.6 0.1 2.7 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF508 PF04370.7 KEG06987.1 - 0.073 12.7 0.5 0.17 11.5 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Shisa PF13908.1 KEG06988.1 - 0.032 14.4 2.9 0.033 14.3 0.4 2.0 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.1 KEG06988.1 - 0.069 13.5 1.3 0.27 11.6 0.2 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.1 KEG06989.1 - 0.0027 17.8 7.4 0.077 13.1 1.5 2.1 2 0 0 2 2 2 2 Wnt and FGF inhibitory regulator EphA2_TM PF14575.1 KEG06989.1 - 0.079 13.3 0.6 16 5.9 0.1 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain OAD_gamma PF04277.8 KEG06989.1 - 1.4 9.3 5.0 0.74 10.2 0.3 2.5 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain EphA2_TM PF14575.1 KEG06990.1 - 0.041 14.2 0.1 0.065 13.6 0.1 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Rab5ip PF07019.7 KEG06990.1 - 0.085 13.0 0.5 0.15 12.2 0.2 1.5 1 1 0 1 1 1 0 Rab5-interacting protein (Rab5ip) Shisa PF13908.1 KEG06990.1 - 0.22 11.6 5.1 0.25 11.5 3.3 1.3 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator CTD PF12815.2 KEG06991.1 - 1.3 9.4 6.8 1.7 9.0 4.7 1.2 1 0 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 Transket_pyr PF02779.19 KEG06995.1 - 1.8e-59 200.2 0.0 2.7e-59 199.6 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 KEG06995.1 - 6.4e-48 162.9 0.0 1.1e-47 162.2 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component NIPSNAP PF07978.8 KEG06996.1 - 9.5e-16 57.6 0.2 3e-15 56.0 0.1 1.7 2 0 0 2 2 2 1 NIPSNAP GAF_2 PF13185.1 KEG06997.1 - 0.0063 17.0 0.1 0.0076 16.7 0.0 1.1 1 0 0 1 1 1 1 GAF domain Peripla_BP_6 PF13458.1 KEG06998.1 - 3.6e-14 52.8 4.1 1e-11 44.8 1.3 2.9 3 0 0 3 3 3 2 Periplasmic binding protein Guanylate_cyc PF00211.15 KEG06998.1 - 3e-07 29.9 0.0 5.7e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Adeno_E3_CR2 PF02439.10 KEG06998.1 - 0.058 12.9 0.1 0.18 11.3 0.1 1.8 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Guanylate_cyc PF00211.15 KEG06999.1 - 8.4e-22 77.4 0.0 1.1e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LINES_N PF14694.1 KEG07000.1 - 0.023 14.0 0.0 0.058 12.6 0.0 1.5 1 1 0 1 1 1 0 Lines N-terminus IQ PF00612.22 KEG07001.1 - 0.91 9.3 6.7 8.1 6.3 0.5 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif ECH PF00378.15 KEG07004.1 - 2.6e-39 134.8 0.2 1.1e-31 109.8 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase family Carboxyl_trans PF01039.17 KEG07004.1 - 0.033 12.5 0.0 0.051 11.9 0.0 1.2 1 0 0 1 1 1 0 Carboxyl transferase domain ECH_C PF13766.1 KEG07004.1 - 0.052 13.6 0.1 2 8.5 0.0 2.3 2 0 0 2 2 2 0 2-enoyl-CoA Hydratase C-terminal region RRM_1 PF00076.17 KEG07005.1 - 7.8e-16 57.4 0.0 2.4e-15 55.8 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG07005.1 - 7.9e-13 48.1 0.0 2.2e-12 46.7 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG07005.1 - 1.1e-07 31.6 0.0 1.9e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peripla_BP_6 PF13458.1 KEG07006.1 - 2.3e-11 43.6 1.9 1.1e-05 25.0 0.0 2.5 2 1 0 2 2 2 2 Periplasmic binding protein Guanylate_cyc PF00211.15 KEG07006.1 - 0.075 12.3 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain COG4 PF08318.7 KEG07009.1 - 2.1e-25 89.2 0.0 2.5e-25 88.9 0.0 1.0 1 0 0 1 1 1 1 COG4 transport protein RINT1_TIP1 PF04437.8 KEG07010.1 - 0.0072 14.9 0.0 0.0087 14.6 0.0 1.1 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Surp PF01805.15 KEG07011.1 - 1.9e-13 49.8 2.2 1.9e-13 49.8 0.1 1.9 2 0 0 2 2 2 1 Surp module Peptidase_M8 PF01457.11 KEG07012.1 - 1.1e-131 439.8 0.0 1.3e-131 439.4 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin EphA2_TM PF14575.1 KEG07013.1 - 0.15 12.5 0.2 0.27 11.6 0.1 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain IncA PF04156.9 KEG07013.1 - 0.21 11.1 0.1 0.4 10.2 0.0 1.4 1 0 0 1 1 1 0 IncA protein PARP PF00644.15 KEG07014.1 - 5.9e-65 218.5 0.0 1.3e-64 217.4 0.0 1.6 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 KEG07014.1 - 6e-42 142.4 0.0 1.1e-41 141.6 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 KEG07014.1 - 6.8e-27 93.2 0.7 1.5e-26 92.1 0.5 1.6 1 0 0 1 1 1 1 WGR domain SSV1_ORF_D-335 PF07935.6 KEG07014.1 - 2.8 7.7 5.2 1.5 8.6 0.3 2.7 2 1 0 2 2 2 0 ORF D-335-like protein Myosin_TH1 PF06017.8 KEG07015.1 - 0.00088 18.6 0.0 0.0019 17.5 0.0 1.5 1 0 0 1 1 1 1 Myosin tail DivIC PF04977.10 KEG07015.1 - 3.2 7.2 8.5 0.38 10.2 0.6 2.7 2 1 1 3 3 3 0 Septum formation initiator FtsA PF14450.1 KEG07016.1 - 0.15 11.8 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Cell division protein FtsA LRR_4 PF12799.2 KEG07017.1 - 1.3e-30 104.5 13.1 0.0085 15.7 0.0 12.1 7 4 8 15 15 15 13 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG07017.1 - 4.8e-18 64.6 17.7 0.0016 18.1 0.1 9.0 6 2 4 10 10 10 6 Leucine rich repeat LRR_6 PF13516.1 KEG07017.1 - 2.7e-17 60.8 6.3 0.44 10.7 0.0 14.6 17 0 0 17 17 17 2 Leucine Rich repeat LRR_1 PF00560.28 KEG07017.1 - 0.0054 16.5 19.7 81 3.8 0.0 11.4 13 2 2 15 15 15 0 Leucine Rich Repeat LRR_7 PF13504.1 KEG07017.1 - 0.018 15.1 28.1 56 4.6 0.0 13.3 15 1 0 15 15 15 0 Leucine rich repeat LRR_9 PF14580.1 KEG07017.1 - 0.06 12.9 7.5 3.2 7.2 0.0 4.7 3 2 2 5 5 5 0 Leucine-rich repeat Galactosyl_T PF01762.16 KEG07023.1 - 0.01 15.4 0.0 1.6 8.2 0.0 3.1 3 1 0 3 3 3 0 Galactosyltransferase Galactosyl_T PF01762.16 KEG07024.1 - 0.00057 19.5 0.0 0.22 11.1 0.0 3.2 3 1 0 3 3 3 1 Galactosyltransferase DUF2417 PF10329.4 KEG07024.1 - 0.021 14.2 0.3 0.031 13.6 0.2 1.2 1 0 0 1 1 1 0 Region of unknown function (DUF2417) SDF PF00375.13 KEG07024.1 - 0.088 11.5 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Sodium:dicarboxylate symporter family Dpy-30 PF05186.8 KEG07026.1 - 8.1e-16 57.2 0.0 1.1e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif RIIa PF02197.12 KEG07026.1 - 0.0081 15.5 0.0 0.017 14.5 0.0 1.6 1 1 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit zf-CDGSH PF09360.5 KEG07028.1 - 8.4e-28 95.9 10.0 1.9e-15 56.4 2.0 2.2 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type GcrA PF07750.6 KEG07028.1 - 0.4 10.8 1.7 0.75 9.9 0.0 1.9 2 0 0 2 2 2 0 GcrA cell cycle regulator Bystin PF05291.6 KEG07030.1 - 2.1e-109 365.1 0.1 3e-109 364.6 0.1 1.1 1 0 0 1 1 1 1 Bystin ATP-synt_E_2 PF08112.6 KEG07031.1 - 0.032 14.2 3.8 0.82 9.7 0.5 3.0 3 0 0 3 3 3 0 ATP synthase epsilon subunit Jnk-SapK_ap_N PF09744.4 KEG07031.1 - 0.91 9.4 15.3 5.4 6.9 3.8 2.5 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF3552 PF12072.3 KEG07031.1 - 2.3 7.4 36.2 0.093 11.9 12.7 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF3552) CAP_N PF01213.14 KEG07031.1 - 3.9 6.6 9.8 0.74 9.0 0.8 2.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DUF2624 PF11116.3 KEG07032.1 - 0.01 16.3 0.0 0.016 15.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2624) PBP1_TM PF14812.1 KEG07032.1 - 2.3 8.6 7.3 3.7 7.9 4.8 1.6 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MRI PF15325.1 KEG07032.1 - 3.6 8.5 6.5 7.9 7.4 4.5 1.8 1 1 0 1 1 1 0 Modulator of retrovirus infection PUF PF00806.14 KEG07034.1 - 2.1e-24 83.5 0.4 3.6e-05 22.9 0.0 5.5 5 0 0 5 5 5 4 Pumilio-family RNA binding repeat DUF1199 PF06712.6 KEG07036.1 - 0.7 9.7 2.9 1.2 9.0 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1199) SIP1 PF04938.7 KEG07037.1 - 0.00076 18.8 0.0 0.0019 17.5 0.0 1.6 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Glycolytic PF00274.14 KEG07039.1 - 1.2e-145 484.3 0.0 1.3e-145 484.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Lipid_DES PF08557.5 KEG07041.1 - 0.013 14.7 0.0 0.033 13.4 0.0 1.7 1 0 0 1 1 1 0 Sphingolipid Delta4-desaturase (DES) MFS_1 PF07690.11 KEG07042.1 - 8.5e-13 47.7 25.7 1.1e-11 44.1 11.4 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 KEG07042.1 - 6.6e-10 38.6 12.6 6.6e-10 38.6 8.7 2.5 2 1 0 2 2 2 1 Nodulin-like DUF1722 PF08349.6 KEG07042.1 - 0.09 12.6 0.0 0.39 10.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DUF1129 PF06570.6 KEG07042.1 - 2.8 7.1 10.5 0.77 9.0 2.6 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1129) CoA_trans PF01144.18 KEG07043.1 - 1.9e-73 246.2 0.2 7.6e-52 175.6 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase Ebola_NP PF05505.7 KEG07044.1 - 0.48 8.4 2.8 0.77 7.7 2.0 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein SNase PF00565.12 KEG07046.1 - 3.6e-05 23.9 0.0 5.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Peptidase_M8 PF01457.11 KEG07047.1 - 2.9e-97 326.1 6.8 1.5e-56 191.8 2.2 2.1 2 0 0 2 2 2 2 Leishmanolysin Reprolysin_5 PF13688.1 KEG07047.1 - 0.0017 18.3 0.0 0.0034 17.3 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.19 KEG07047.1 - 0.096 12.4 0.0 0.37 10.5 0.0 1.8 1 1 1 2 2 2 0 Matrixin KAR PF15222.1 KEG07047.1 - 0.097 12.7 1.3 0.41 10.7 0.0 2.4 2 1 1 3 3 3 0 Kidney androgen-regulated zf-CCHC PF00098.18 KEG07049.1 - 0.00048 19.9 1.5 0.00083 19.1 1.1 1.4 1 0 0 1 1 1 1 Zinc knuckle XhlA PF10779.4 KEG07049.1 - 0.52 10.2 3.0 0.94 9.4 2.1 1.4 1 0 0 1 1 1 0 Haemolysin XhlA CCDC155 PF14662.1 KEG07049.1 - 8.1 5.9 10.2 0.76 9.3 3.8 1.6 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 CLPTM1 PF05602.7 KEG07052.1 - 0.56 8.8 3.4 0.85 8.2 2.4 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) BAF1_ABF1 PF04684.8 KEG07052.1 - 0.66 8.7 7.7 1.2 7.9 5.3 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Metallophos PF00149.23 KEG07053.1 - 2.2e-31 108.8 0.0 5.1e-31 107.6 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4312 PF14189.1 KEG07053.1 - 0.14 11.9 0.5 0.77 9.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4312) Endonuclease_NS PF01223.18 KEG07059.1 - 5.4e-24 84.9 0.0 9.6e-24 84.1 0.0 1.4 1 1 0 1 1 1 1 DNA/RNA non-specific endonuclease Peptidase_M1 PF01433.15 KEG07060.1 - 4.8e-128 427.5 0.0 7.1e-128 427.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 KEG07060.1 - 3.6e-46 157.9 2.0 1.4e-45 155.9 0.9 2.2 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KEG07060.1 - 3.6e-20 72.2 0.6 6.5e-20 71.4 0.4 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily ELMO_CED12 PF04727.8 KEG07061.1 - 3.4e-27 95.0 0.0 4.6e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 ELMO/CED-12 family ELMO_CED12 PF04727.8 KEG07062.1 - 0.00019 21.0 0.0 0.00022 20.8 0.0 1.1 1 0 0 1 1 1 1 ELMO/CED-12 family Pkinase PF00069.20 KEG07063.1 - 2.8e-46 157.7 0.0 9.3e-46 156.0 0.0 1.8 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG07063.1 - 2.8e-30 105.2 0.0 5.1e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG07063.1 - 1.8e-05 23.8 0.0 3.6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like PH PF00169.24 KEG07063.1 - 0.0012 18.9 0.2 0.0051 16.9 0.2 2.0 1 1 0 1 1 1 1 PH domain PH_9 PF15410.1 KEG07063.1 - 0.0097 16.0 0.3 0.023 14.8 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.1 KEG07063.1 - 0.087 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain YL1 PF05764.8 KEG07066.1 - 4.1e-09 36.4 10.4 6.4e-09 35.7 7.2 1.3 1 1 0 1 1 1 1 YL1 nuclear protein Mif2_N PF15624.1 KEG07066.1 - 0.014 16.0 1.5 0.021 15.4 0.7 1.5 1 1 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Kelch_1 PF01344.20 KEG07067.1 - 6.3e-11 41.6 0.3 0.0003 20.2 0.2 3.8 3 1 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 KEG07067.1 - 2.4e-09 36.9 0.2 0.00025 21.0 0.0 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 KEG07067.1 - 6.5e-09 35.5 0.9 0.00016 21.5 0.0 2.7 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 KEG07067.1 - 1.6e-08 34.2 10.7 0.00034 20.3 0.0 4.2 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.10 KEG07067.1 - 3.3e-07 29.8 0.3 0.11 12.3 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 KEG07067.1 - 0.0017 18.4 22.0 0.77 10.0 0.1 5.9 7 1 0 7 7 7 3 Galactose oxidase, central domain SQS_PSY PF00494.14 KEG07073.1 - 6e-40 137.2 1.8 9.4e-40 136.5 1.2 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase AA_synth PF06684.6 KEG07075.1 - 0.076 12.3 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Amino acid synthesis Sec8_exocyst PF04048.9 KEG07077.1 - 5.9e-10 38.9 0.0 1.4e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 KEG07077.1 - 7e-06 25.1 0.4 1.3e-05 24.2 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) SDA1 PF05285.7 KEG07077.1 - 1.3 8.1 28.2 0.31 10.2 15.9 2.1 2 0 0 2 2 2 0 SDA1 RNase_H2-Ydr279 PF09468.5 KEG07078.1 - 0.96 8.5 5.7 2.2 7.3 3.9 1.6 1 1 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Lipase_GDSL_2 PF13472.1 KEG07079.1 - 1.3e-05 25.4 0.5 0.0001 22.4 0.3 2.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KEG07079.1 - 0.00066 19.5 0.0 0.0025 17.6 0.0 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase RGM_N PF06535.7 KEG07080.1 - 0.021 14.8 0.2 0.024 14.6 0.1 1.3 1 1 0 1 1 1 0 Repulsive guidance molecule (RGM) N-terminus AKAP7_NLS PF10469.4 KEG07081.1 - 1.4e-23 83.6 0.0 2.2e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.1 KEG07081.1 - 1.1e-05 25.2 0.0 1.8e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily Myticin-prepro PF10690.4 KEG07084.1 - 0.097 12.7 1.6 0.17 11.9 1.1 1.4 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel EB1 PF03271.12 KEG07085.1 - 2.9e-11 43.2 0.0 4.1e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 EB1-like C-terminal motif DUF630 PF04783.7 KEG07086.1 - 0.48 10.3 5.1 0.39 10.6 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF630) Ribosomal_L37ae PF01780.14 KEG07087.1 - 4.2e-36 122.6 4.9 4.7e-36 122.5 3.4 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family C1_1 PF00130.17 KEG07087.1 - 0.00085 18.9 1.8 0.0012 18.4 1.2 1.2 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) A2L_zn_ribbon PF08792.5 KEG07087.1 - 0.025 14.0 0.9 2.5 7.6 0.0 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain UPF0547 PF10571.4 KEG07087.1 - 0.052 13.2 1.2 6.8 6.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Zn_Tnp_IS1595 PF12760.2 KEG07087.1 - 0.099 12.4 2.4 0.16 11.8 1.7 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Carla_C4 PF01623.12 KEG07087.1 - 0.12 12.1 1.6 0.14 11.9 1.1 1.4 1 1 0 1 1 1 0 Carlavirus putative nucleic acid binding protein NOB1_Zn_bind PF08772.6 KEG07087.1 - 0.12 12.2 3.6 1.2 8.9 2.5 2.2 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zf-HIT PF04438.11 KEG07087.1 - 0.21 11.2 2.6 0.24 11.0 0.3 1.9 2 0 0 2 2 2 0 HIT zinc finger GFA PF04828.9 KEG07087.1 - 0.34 10.8 2.8 1.1 9.2 0.3 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-C4_ClpX PF06689.8 KEG07087.1 - 7 6.2 6.7 1.3 8.5 1.9 1.8 2 0 0 2 2 2 0 ClpX C4-type zinc finger zf-C3HC4_2 PF13923.1 KEG07088.1 - 3e-11 43.1 7.7 4.8e-11 42.4 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEG07088.1 - 3.2e-11 42.8 8.2 5.4e-11 42.1 5.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KEG07088.1 - 5.7e-10 38.6 5.3 9.4e-10 37.9 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEG07088.1 - 1.1e-09 37.7 4.2 1.7e-09 37.2 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEG07088.1 - 2.6e-09 36.6 4.2 4.3e-09 35.9 2.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KEG07088.1 - 3.4e-09 36.4 6.9 6.2e-09 35.5 4.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KEG07088.1 - 8.6e-09 34.9 1.6 1.3e-08 34.3 0.4 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 KEG07088.1 - 8.8e-05 22.2 1.3 0.00018 21.2 0.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 KEG07088.1 - 0.0003 20.8 6.7 0.0003 20.8 4.6 2.4 2 1 0 2 2 2 1 RING-H2 zinc finger Rtf2 PF04641.7 KEG07088.1 - 0.00047 19.4 0.0 0.00068 18.9 0.0 1.3 1 1 0 1 1 1 1 Rtf2 RING-finger Prok-RING_4 PF14447.1 KEG07088.1 - 0.015 14.7 5.6 0.12 11.9 3.9 2.4 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 DUF912 PF06024.7 KEG07088.1 - 0.016 15.2 2.4 0.88 9.6 0.1 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Pex14_N PF04695.8 KEG07088.1 - 0.02 14.9 11.2 0.27 11.2 1.0 2.1 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-RING_6 PF14835.1 KEG07088.1 - 0.038 13.7 3.4 0.077 12.7 2.4 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 KEG07088.1 - 0.081 12.5 6.7 0.33 10.5 4.7 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Vma12 PF11712.3 KEG07088.1 - 0.091 12.4 0.5 0.17 11.5 0.3 1.7 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase IBR PF01485.16 KEG07088.1 - 1 9.2 8.2 1.1 9.1 4.4 2.1 1 1 0 1 1 1 0 IBR domain DUF4660 PF15559.1 KEG07088.1 - 3.2 7.8 6.4 1.3 9.1 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4660) FAD_binding_2 PF00890.19 KEG07090.1 - 1.3e-86 291.0 0.3 2e-86 290.4 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain ApbE PF02424.10 KEG07090.1 - 5.6e-59 199.4 0.0 9.9e-59 198.6 0.0 1.3 1 0 0 1 1 1 1 ApbE family DAO PF01266.19 KEG07090.1 - 2.7e-08 33.1 3.2 9.7e-06 24.7 0.9 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KEG07090.1 - 7.9e-08 32.4 1.0 7.8e-05 22.6 0.4 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KEG07090.1 - 8.8e-08 31.6 7.6 1.6e-07 30.7 4.4 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 KEG07090.1 - 2.1e-07 30.1 4.1 4.7e-06 25.7 1.2 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_1 PF00175.16 KEG07090.1 - 2.6e-06 27.9 0.0 9.2e-06 26.1 0.0 2.0 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_8 PF13450.1 KEG07090.1 - 3.9e-06 26.7 3.1 6.1e-05 22.9 0.9 3.7 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KEG07090.1 - 2.5e-05 22.9 5.8 0.00057 18.4 2.3 2.5 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.16 KEG07090.1 - 0.0044 16.6 0.7 0.011 15.3 0.5 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 KEG07090.1 - 0.012 14.6 0.7 0.021 13.8 0.5 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 KEG07090.1 - 0.012 15.6 2.7 1.5 8.8 0.7 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEG07090.1 - 0.023 15.1 3.4 0.023 15.1 0.6 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEG07090.1 - 0.059 12.4 1.2 0.23 10.5 0.9 2.0 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 KEG07090.1 - 0.14 11.0 2.1 0.39 9.5 0.7 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein SLA_LP_auto_ag PF05889.8 KEG07091.1 - 4.2e-44 150.5 0.0 8.5e-44 149.5 0.0 1.4 1 1 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Beta_elim_lyase PF01212.16 KEG07091.1 - 0.04 13.0 0.1 0.049 12.7 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase FbpA PF05833.6 KEG07092.1 - 5.2e-36 124.1 4.7 5.2e-36 124.1 3.2 2.8 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF3441 PF11923.3 KEG07092.1 - 4.2e-23 81.0 0.0 4.2e-23 81.0 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3441) DUF814 PF05670.8 KEG07092.1 - 4.1e-07 29.7 0.0 6e-05 22.8 0.0 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF814) PWWP PF00855.12 KEG07093.1 - 7.9e-10 38.8 0.0 1e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 PWWP domain Telomere_Sde2 PF13019.1 KEG07093.1 - 0.045 13.4 0.0 0.05 13.2 0.0 1.1 1 0 0 1 1 1 0 Telomere stability and silencing GTP_EFTU PF00009.22 KEG07095.1 - 2.1e-22 79.4 0.0 3.5e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KEG07095.1 - 8.5e-14 51.5 0.1 2.3e-13 50.1 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KEG07095.1 - 2.8e-06 27.3 1.8 6e-06 26.2 0.3 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KEG07095.1 - 0.0016 18.4 0.0 0.021 14.7 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase MobB PF03205.9 KEG07095.1 - 0.031 13.9 0.2 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DND1_DSRM PF14709.1 KEG07097.1 - 0.0028 17.8 0.0 0.012 15.8 0.0 2.1 2 0 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.20 KEG07097.1 - 0.046 14.2 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding motif CDC73 PF05179.9 KEG07097.1 - 0.069 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family Mucin PF01456.12 KEG07099.1 - 3e-07 30.3 4.6 3.9e-07 29.9 3.2 1.1 1 0 0 1 1 1 1 Mucin-like glycoprotein GCN5L1 PF06320.8 KEG07099.1 - 0.12 12.1 0.7 0.19 11.5 0.5 1.3 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) MCP_N PF05581.7 KEG07100.1 - 0.15 12.2 1.6 17 5.6 0.2 2.6 2 0 0 2 2 2 0 Vibrio chemotaxis protein N terminus DUF1704 PF08014.6 KEG07101.1 - 0.035 13.1 0.2 0.058 12.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1704) Mucin PF01456.12 KEG07101.1 - 0.059 13.1 0.4 0.059 13.1 0.2 3.6 3 1 0 3 3 3 0 Mucin-like glycoprotein TFIIA PF03153.8 KEG07103.1 - 4.8 6.9 7.4 5.9 6.6 5.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit COG5 PF10392.4 KEG07104.1 - 0.002 18.0 5.8 0.59 10.0 1.0 3.2 2 0 0 2 2 2 2 Golgi transport complex subunit 5 Phage_GP20 PF06810.6 KEG07104.1 - 0.054 12.9 5.7 2.5 7.5 0.5 4.2 3 1 1 4 4 4 0 Phage minor structural protein GP20 FH2 PF02181.18 KEG07104.1 - 0.055 12.3 8.7 0.012 14.5 1.6 2.7 3 0 0 3 3 3 0 Formin Homology 2 Domain DUF2935 PF11155.3 KEG07104.1 - 0.11 12.6 0.8 1 9.4 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) Bacillus_HBL PF05791.6 KEG07104.1 - 0.15 11.4 7.8 0.11 11.8 0.8 3.3 3 1 1 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) AAA_13 PF13166.1 KEG07104.1 - 0.38 9.1 6.1 1.1 7.5 4.3 1.9 1 1 0 1 1 1 0 AAA domain DUF641 PF04859.7 KEG07104.1 - 0.71 9.6 23.2 0.056 13.1 0.9 4.7 3 1 2 5 5 5 0 Plant protein of unknown function (DUF641) Fib_alpha PF08702.5 KEG07104.1 - 0.77 9.8 11.7 6 6.9 0.1 4.4 4 1 2 6 6 6 0 Fibrinogen alpha/beta chain family Med9 PF07544.8 KEG07104.1 - 2 8.2 17.0 0.32 10.7 0.4 4.5 3 1 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Prefoldin PF02996.12 KEG07104.1 - 2.5 7.7 15.9 1.2 8.8 0.2 4.8 4 1 1 5 5 5 0 Prefoldin subunit Prominin PF05478.6 KEG07104.1 - 3.9 4.8 9.9 3.8 4.9 1.0 3.1 3 1 0 3 3 3 0 Prominin Tup_N PF08581.5 KEG07105.1 - 0.19 11.9 0.1 0.19 11.9 0.0 3.5 3 0 0 3 3 3 0 Tup N-terminal Phage_Mu_Gam PF07352.7 KEG07105.1 - 0.69 9.4 4.6 6.2 6.3 0.2 2.6 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein DUF342 PF03961.8 KEG07105.1 - 1.1 7.5 9.5 0.53 8.6 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF342) Spc7 PF08317.6 KEG07105.1 - 5 5.6 10.0 1.6 7.2 0.2 2.6 2 0 0 2 2 2 0 Spc7 kinetochore protein Ftsk_gamma PF09397.5 KEG07106.1 - 0.016 14.9 0.1 0.03 14.0 0.0 1.5 2 0 0 2 2 2 0 Ftsk gamma domain RINGv PF12906.2 KEG07107.1 - 1.3e-12 47.5 10.6 2.5e-12 46.6 7.4 1.5 1 0 0 1 1 1 1 RING-variant domain Mem_trans PF03547.13 KEG07107.1 - 0.0013 17.1 0.0 0.031 12.6 0.0 2.4 1 1 0 1 1 1 1 Membrane transport protein zf-P11 PF03854.9 KEG07107.1 - 0.056 12.9 0.3 0.15 11.5 0.2 1.7 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_2 PF13639.1 KEG07107.1 - 0.081 12.7 6.4 0.17 11.7 4.4 1.6 1 0 0 1 1 1 0 Ring finger domain DUF389 PF04087.9 KEG07107.1 - 0.3 11.0 7.9 0.15 11.9 1.2 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF389) PHD PF00628.24 KEG07107.1 - 0.39 10.4 7.6 0.8 9.4 5.2 1.6 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.3 KEG07107.1 - 0.64 10.0 4.7 1.3 9.0 3.2 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.1 KEG07107.1 - 1.6 8.4 6.0 3.1 7.5 4.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Band_7 PF01145.20 KEG07108.1 - 2.5e-23 82.8 0.0 3.3e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Pkinase PF00069.20 KEG07109.1 - 4e-08 32.7 0.0 4.8e-08 32.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG07109.1 - 0.00033 19.7 0.0 0.00036 19.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Baculo_Y142 PF04913.7 KEG07109.1 - 0.0065 14.8 0.0 0.0075 14.6 0.0 1.0 1 0 0 1 1 1 1 Baculovirus Y142 protein Pkinase PF00069.20 KEG07110.1 - 1.2e-32 113.1 0.0 1.8e-32 112.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG07110.1 - 9.6e-08 31.4 0.0 1.8e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase AMP-binding PF00501.23 KEG07111.1 - 1.7e-83 280.3 0.0 2.3e-83 279.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme TcdB_toxin_midN PF12256.3 KEG07111.1 - 0.13 11.6 0.1 0.21 11.0 0.1 1.2 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region AMP-binding PF00501.23 KEG07112.1 - 6.1e-80 268.6 0.0 8.8e-80 268.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Sec7 PF01369.15 KEG07113.1 - 2.2e-58 197.0 0.0 5e-58 195.9 0.0 1.6 1 0 0 1 1 1 1 Sec7 domain DUF1981 PF09324.5 KEG07113.1 - 1.6e-20 72.4 1.4 3.4e-19 68.1 0.0 3.4 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) Sec7_N PF12783.2 KEG07113.1 - 3.5e-16 59.0 1.2 3.5e-16 59.0 0.9 3.0 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Clathrin_H_link PF13838.1 KEG07113.1 - 0.0016 18.2 0.1 3.3 7.6 0.0 2.7 2 0 0 2 2 2 2 Clathrin-H-link Nop14 PF04147.7 KEG07115.1 - 3.2 5.5 6.6 0.16 9.8 1.0 1.4 2 0 0 2 2 2 0 Nop14-like family DUF1876 PF08962.6 KEG07116.1 - 0.044 13.5 0.9 0.099 12.4 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1876) Protocadherin PF08374.6 KEG07116.1 - 0.077 12.6 0.9 0.091 12.3 0.6 1.2 1 0 0 1 1 1 0 Protocadherin SpoIIIAH PF12685.2 KEG07116.1 - 3.6 7.0 7.6 4.1 6.8 5.2 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein LSM PF01423.17 KEG07119.1 - 1.6e-13 49.9 1.0 2.3e-13 49.4 0.7 1.1 1 0 0 1 1 1 1 LSM domain Trypsin_2 PF13365.1 KEG07120.1 - 5.1e-06 26.4 0.0 1.1e-05 25.4 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF3759 PF12585.3 KEG07122.1 - 0.09 12.6 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3759) PEHE PF15275.1 KEG07122.1 - 3.8 7.9 7.9 23 5.4 5.4 2.1 1 1 1 2 2 2 0 PEHE domain Ras PF00071.17 KEG07123.1 - 1.3e-36 125.4 0.0 4.5e-36 123.6 0.0 1.7 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KEG07123.1 - 4e-15 56.3 0.0 5.2e-14 52.7 0.0 2.0 1 1 1 2 2 2 1 Miro-like protein Arf PF00025.16 KEG07123.1 - 1.8e-06 27.3 0.0 2.3e-05 23.7 0.0 2.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KEG07123.1 - 0.03 13.7 0.0 0.097 12.0 0.0 1.7 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KEG07123.1 - 0.043 13.7 0.0 0.074 13.0 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF258 PF03193.11 KEG07123.1 - 0.049 12.8 0.0 0.11 11.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 KEG07123.1 - 0.16 12.1 0.0 0.34 11.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain UPF0160 PF03690.8 KEG07124.1 - 7.5e-121 403.4 0.0 8.9e-121 403.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) PrmA PF06325.8 KEG07126.1 - 2.2e-12 46.7 0.0 3.1e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 KEG07126.1 - 2.3e-12 47.4 0.0 5.1e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEG07126.1 - 2.4e-08 34.0 0.7 2.1e-07 30.9 0.5 2.4 1 1 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 KEG07126.1 - 1e-07 31.7 0.0 1.1e-06 28.4 0.0 2.2 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_31 PF13847.1 KEG07126.1 - 1e-07 31.6 0.0 1.8e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 KEG07126.1 - 1.8e-07 30.4 0.0 2.4e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_16 PF10294.4 KEG07126.1 - 1.8e-06 27.4 0.0 3e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 KEG07126.1 - 2.5e-06 26.9 0.0 6.5e-06 25.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain PCMT PF01135.14 KEG07126.1 - 6e-06 25.9 0.0 1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.10 KEG07126.1 - 4.1e-05 23.0 0.0 6.5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 RrnaAD PF00398.15 KEG07126.1 - 7.8e-05 21.8 0.0 0.00015 20.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.7 KEG07126.1 - 0.00012 22.5 0.0 0.00059 20.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEG07126.1 - 0.0059 16.3 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KEG07126.1 - 0.013 14.6 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 KEG07126.1 - 0.021 15.1 0.0 0.077 13.3 0.0 2.1 1 1 1 2 2 1 0 Methyltransferase domain Methyltransf_24 PF13578.1 KEG07126.1 - 0.03 15.1 0.0 0.1 13.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 KEG07126.1 - 0.032 14.6 0.0 0.079 13.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 KEG07126.1 - 0.1 12.1 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 TLD PF07534.11 KEG07127.1 - 4.7e-11 42.8 0.0 6.8e-10 39.0 0.0 2.0 1 1 0 1 1 1 1 TLD Acyl-CoA_dh_1 PF00441.19 KEG07128.1 - 1.7e-53 180.7 1.2 2.7e-53 180.1 0.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KEG07128.1 - 2.7e-25 89.1 1.9 2.8e-25 89.0 0.2 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KEG07128.1 - 4.8e-25 88.3 1.1 7.9e-25 87.6 0.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KEG07128.1 - 4.5e-21 74.1 0.7 7.9e-21 73.3 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain HpaB_N PF11794.3 KEG07128.1 - 0.0046 16.3 0.2 0.015 14.7 0.1 1.8 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal E1-E2_ATPase PF00122.15 KEG07129.1 - 3.2e-53 180.1 3.4 3.2e-53 180.1 2.3 2.2 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KEG07129.1 - 7.5e-40 136.3 3.0 1.9e-39 135.0 0.5 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KEG07129.1 - 1.8e-26 93.8 0.0 4.4e-25 89.3 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEG07129.1 - 1.8e-13 50.2 0.0 4.1e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KEG07129.1 - 6.9e-12 44.6 0.0 1.5e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KEG07129.1 - 1.3e-09 38.5 0.0 3.6e-09 37.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KEG07129.1 - 5.8e-05 22.7 0.9 0.00012 21.7 0.3 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1897 PF09005.5 KEG07129.1 - 0.02 14.3 0.3 0.043 13.2 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1897) RuBisCO_small PF00101.15 KEG07134.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase, small chain UAA PF08449.6 KEG07136.1 - 2.4e-44 151.4 18.8 3.5e-30 104.9 6.4 2.0 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.15 KEG07136.1 - 2.5e-08 34.0 6.0 2.5e-08 34.0 4.1 2.6 3 0 0 3 3 3 1 EamA-like transporter family TPT PF03151.11 KEG07136.1 - 0.00019 21.1 11.8 0.00019 21.1 8.2 2.7 2 2 0 3 3 3 1 Triose-phosphate Transporter family DUF308 PF03729.8 KEG07136.1 - 0.013 15.4 0.3 4.2 7.4 0.1 3.0 2 1 0 2 2 2 0 Short repeat of unknown function (DUF308) UPF0546 PF10639.4 KEG07136.1 - 0.048 13.4 5.9 0.034 13.9 2.0 2.3 2 1 0 2 2 2 0 Uncharacterised protein family UPF0546 DUF606 PF04657.8 KEG07136.1 - 0.079 13.0 5.8 0.37 10.8 0.3 2.7 2 1 0 2 2 2 0 Protein of unknown function, DUF606 Mucin PF01456.12 KEG07137.1 - 0.00018 21.3 11.0 0.00018 21.3 7.6 5.1 1 1 2 3 3 3 1 Mucin-like glycoprotein Atg14 PF10186.4 KEG07137.1 - 9.4 5.0 9.9 18 4.1 6.9 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Tropomyosin_1 PF12718.2 KEG07138.1 - 0.076 12.8 42.2 0.41 10.4 14.1 3.6 1 1 2 3 3 3 0 Tropomyosin like IQ-like PF15157.1 KEG07138.1 - 0.12 12.5 0.5 0.5 10.5 0.0 2.3 2 1 0 2 2 2 0 IQ-like Laminin_I PF06008.9 KEG07138.1 - 0.15 11.3 35.0 1.1 8.4 5.3 3.3 1 1 1 3 3 3 0 Laminin Domain I Tweety PF04906.8 KEG07139.1 - 3.8 5.8 5.8 0.79 8.0 1.0 1.9 2 0 0 2 2 2 0 Tweety Maf1 PF09174.5 KEG07141.1 - 1.1e-33 116.6 0.0 2e-33 115.7 0.0 1.4 1 1 0 1 1 1 1 Maf1 regulator Prefoldin_2 PF01920.15 KEG07142.1 - 0.015 15.0 3.6 0.035 13.8 2.5 1.7 1 0 0 1 1 1 0 Prefoldin subunit Tht1 PF04163.7 KEG07142.1 - 0.042 12.2 0.9 0.041 12.2 0.6 1.0 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein DUF3710 PF12502.3 KEG07142.1 - 0.045 13.0 6.3 0.06 12.6 4.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3710) EMP24_GP25L PF01105.19 KEG07142.1 - 0.47 10.1 4.5 0.75 9.4 3.1 1.5 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Dor1 PF04124.7 KEG07142.1 - 1 7.7 9.4 1.3 7.4 6.5 1.1 1 0 0 1 1 1 0 Dor1-like family DUF3994 PF13159.1 KEG07142.1 - 1.5 9.0 0.0 1.5 9.0 0.0 3.0 1 1 0 2 2 2 0 Domain of unknown function (DUF3994) TAF8_C PF10406.4 KEG07142.1 - 3.1 7.9 4.8 0.84 9.7 0.6 2.1 2 0 0 2 2 2 0 Transcription factor TFIID complex subunit 8 C-term DUF1771 PF08590.5 KEG07143.1 - 1.7e-19 69.5 10.3 2.8e-19 68.8 7.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) KH_1 PF00013.24 KEG07143.1 - 3.9e-11 42.4 4.8 5.9e-11 41.8 3.3 1.3 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 KEG07143.1 - 6.2e-09 35.3 1.1 1.3e-08 34.2 0.8 1.5 1 0 0 1 1 1 1 KH domain KH_2 PF07650.12 KEG07143.1 - 1.1e-05 24.8 3.9 1.7e-05 24.2 1.8 2.0 2 0 0 2 2 2 1 KH domain Smr PF01713.16 KEG07143.1 - 0.02 15.1 0.0 0.02 15.1 0.0 2.4 3 2 1 4 4 4 0 Smr domain KH_5 PF13184.1 KEG07143.1 - 0.029 14.1 0.4 0.06 13.1 0.3 1.5 1 0 0 1 1 1 0 NusA-like KH domain DUF4407 PF14362.1 KEG07143.1 - 0.98 8.3 6.6 1.6 7.6 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pkinase PF00069.20 KEG07145.1 - 4.3e-67 225.9 0.0 6e-67 225.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG07145.1 - 2.3e-41 141.6 0.0 3.1e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG07145.1 - 9.6e-07 28.0 0.0 0.026 13.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KEG07145.1 - 0.007 16.1 0.0 0.05 13.3 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KEG07145.1 - 0.092 11.5 0.1 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 HIT PF01230.18 KEG07148.1 - 1.7e-24 86.2 0.3 2.1e-24 85.8 0.2 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KEG07148.1 - 4.7e-14 52.6 0.0 5.7e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 KEG07148.1 - 4.4e-05 23.1 0.3 7.4e-05 22.3 0.2 1.4 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 TRAP-gamma PF07074.7 KEG07149.1 - 2.2e-05 24.0 9.2 0.086 12.3 6.4 2.1 1 1 0 1 1 1 1 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF2976 PF11190.3 KEG07149.1 - 0.028 13.9 0.1 0.062 12.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) Abhydrolase_9_N PF15420.1 KEG07149.1 - 0.098 12.3 0.5 0.15 11.8 0.4 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus DUF2721 PF11026.3 KEG07149.1 - 1.7 8.2 5.2 0.28 10.8 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) VIT_2 PF13757.1 KEG07150.1 - 5e-05 22.6 0.0 7.6e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain DUF4424 PF14415.1 KEG07150.1 - 0.0083 15.6 0.0 0.009 15.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4424) Hamartin PF04388.7 KEG07152.1 - 0.11 11.2 6.5 0.047 12.3 1.3 2.1 2 0 0 2 2 2 0 Hamartin protein DUF3653 PF12375.3 KEG07152.1 - 0.31 11.2 4.9 9 6.6 0.1 3.7 3 0 0 3 3 3 0 Phage protein EBA-175_VI PF11556.3 KEG07154.1 - 0.051 13.6 1.9 0.078 13.0 1.3 1.2 1 0 0 1 1 1 0 Erythrocyte binding antigen 175 DUF4201 PF13870.1 KEG07155.1 - 2.1e-37 128.2 24.4 2.9e-37 127.8 16.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Tnp_P_element PF12017.3 KEG07155.1 - 0.77 8.9 7.8 0.74 9.0 0.3 2.5 1 1 1 2 2 2 0 Transposase protein SNAPc19 PF15497.1 KEG07155.1 - 0.95 9.7 10.6 0.096 12.9 2.1 2.7 1 1 1 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 YjcZ PF13990.1 KEG07155.1 - 1.1 8.2 8.8 0.13 11.3 3.1 1.7 2 1 0 2 2 2 0 YjcZ-like protein NPV_P10 PF05531.7 KEG07155.1 - 4.2 7.6 7.3 4.2 7.6 0.4 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein V_ATPase_I PF01496.14 KEG07155.1 - 6.6 4.4 14.9 1.4 6.6 7.3 1.6 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family PX PF00787.19 KEG07156.1 - 3.2e-09 36.5 0.0 1e-08 34.9 0.0 1.9 1 0 0 1 1 1 1 PX domain Aft1_OSA PF11785.3 KEG07156.1 - 1.8 9.1 11.6 3.1 8.3 2.0 2.6 2 0 0 2 2 2 0 Aft1 osmotic stress response (OSM) domain NDUF_B7 PF05676.8 KEG07157.1 - 0.28 10.6 2.1 0.25 10.7 0.5 1.6 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Extensin-like_C PF06904.7 KEG07158.1 - 0.045 13.5 0.3 0.049 13.4 0.2 1.1 1 0 0 1 1 1 0 Extensin-like protein C-terminus DUF812 PF05667.6 KEG07160.1 - 0.027 12.9 4.4 0.034 12.6 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF1465 PF07323.7 KEG07160.1 - 0.035 13.6 1.3 0.071 12.6 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) Prominin PF05478.6 KEG07160.1 - 0.062 10.8 1.4 0.072 10.6 1.0 1.1 1 0 0 1 1 1 0 Prominin DUF972 PF06156.8 KEG07160.1 - 0.12 12.6 5.6 0.12 12.7 2.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF342 PF03961.8 KEG07160.1 - 0.18 10.1 2.9 0.21 9.9 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 KEG07160.1 - 0.22 9.3 3.5 0.26 9.0 2.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF848 PF05852.6 KEG07160.1 - 0.24 11.2 6.0 0.54 10.1 3.6 1.8 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF3450 PF11932.3 KEG07160.1 - 1 8.5 10.0 1.7 7.8 6.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF904 PF06005.7 KEG07160.1 - 2.8 8.3 11.2 3.1 8.1 3.5 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF904) Pkinase PF00069.20 KEG07162.1 - 7.4e-29 100.6 2.6 1.1e-28 100.1 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG07162.1 - 7.2e-13 48.2 0.0 3.2e-07 29.6 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Activator_LAG-3 PF11498.3 KEG07162.1 - 8.2 5.0 18.3 15 4.2 12.7 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 PPR_2 PF13041.1 KEG07164.1 - 0.084 12.8 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 PPR repeat family Phage_holin_T PF11031.3 KEG07165.1 - 0.029 13.5 0.0 0.042 12.9 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage T holin Porin_OmpG PF09381.5 KEG07165.1 - 0.11 11.5 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Outer membrane protein G (OmpG) DIM PF08194.7 KEG07165.1 - 2.3 8.2 4.8 5.6 7.0 0.2 3.3 3 0 0 3 3 3 0 DIM protein GTP_EFTU PF00009.22 KEG07167.1 - 3.8e-37 127.5 0.5 1.8e-36 125.3 0.4 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KEG07167.1 - 1e-07 31.8 0.1 2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KEG07167.1 - 3.8e-07 30.6 0.1 1.6e-06 28.5 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 KEG07167.1 - 1.6e-05 24.2 0.1 4.7e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 KEG07167.1 - 0.00089 18.7 0.1 0.0024 17.3 0.1 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation IF-2 PF11987.3 KEG07167.1 - 0.0012 18.7 0.0 0.0051 16.6 0.0 2.1 2 0 0 2 2 2 1 Translation-initiation factor 2 Arf PF00025.16 KEG07167.1 - 0.0032 16.7 0.0 0.0059 15.8 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.13 KEG07167.1 - 0.006 15.8 0.1 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KEG07167.1 - 0.0065 16.3 1.4 1 9.1 0.0 3.0 2 1 1 3 3 3 2 Dynamin family Mito_fiss_reg PF05308.6 KEG07171.1 - 0.21 10.8 2.8 0.3 10.4 1.9 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Umbravirus_LDM PF04817.7 KEG07173.1 - 0.01 15.0 3.2 0.01 15.0 2.2 2.0 1 1 1 2 2 2 0 Umbravirus long distance movement (LDM) family HTH_17 PF12728.2 KEG07174.1 - 0.058 13.6 0.0 0.078 13.2 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_5 PF01022.15 KEG07174.1 - 0.33 10.6 1.4 0.99 9.1 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Abhydrolase_6 PF12697.2 KEG07175.1 - 1.1e-21 77.8 1.6 2e-20 73.6 1.1 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEG07175.1 - 1.3e-12 47.7 0.0 5.4e-12 45.6 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEG07175.1 - 5.1e-06 26.2 0.1 0.0022 17.5 0.1 2.7 2 1 0 2 2 2 2 alpha/beta hydrolase fold PGAP1 PF07819.8 KEG07175.1 - 0.0017 18.0 0.0 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Esterase PF00756.15 KEG07175.1 - 0.0019 17.6 0.3 0.0037 16.7 0.0 1.6 2 0 0 2 2 2 1 Putative esterase DUF676 PF05057.9 KEG07175.1 - 0.0049 16.1 0.0 0.0076 15.5 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.10 KEG07175.1 - 0.03 13.2 0.0 0.046 12.6 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_3 PF07859.8 KEG07175.1 - 0.081 12.4 0.1 0.26 10.8 0.1 1.8 2 1 0 2 2 2 0 alpha/beta hydrolase fold Abhydro_lipase PF04083.11 KEG07175.1 - 0.097 12.0 0.0 0.64 9.4 0.0 2.2 3 0 0 3 3 3 0 Partial alpha/beta-hydrolase lipase region EF-hand_8 PF13833.1 KEG07176.1 - 5.2e-18 64.4 2.0 4.2e-05 23.0 0.0 4.1 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_7 PF13499.1 KEG07176.1 - 1.1e-17 63.8 0.4 1.1e-09 38.3 0.5 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KEG07176.1 - 2.9e-16 57.4 4.4 1.4e-06 27.1 0.0 4.9 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 KEG07176.1 - 7.5e-13 47.1 0.8 7e-05 22.3 0.0 4.8 4 1 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.1 KEG07176.1 - 8.5e-07 28.0 2.8 0.012 14.9 0.0 4.9 5 2 1 6 6 6 2 EF hand EF-hand_9 PF14658.1 KEG07176.1 - 3.2e-05 23.7 0.1 0.0016 18.3 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.2 KEG07176.1 - 0.00032 20.3 0.1 0.0029 17.3 0.1 1.9 1 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.5 KEG07176.1 - 0.025 14.5 1.2 0.34 10.9 0.0 2.6 2 1 0 2 2 2 0 Ca2+ insensitive EF hand DUF1014 PF06244.7 KEG07176.1 - 0.04 14.1 0.1 0.051 13.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1014) SPARC_Ca_bdg PF10591.4 KEG07176.1 - 0.087 12.8 0.1 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region MAM33 PF02330.11 KEG07177.1 - 0.00037 20.3 0.0 0.0006 19.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial glycoprotein Tctex-1 PF03645.8 KEG07178.1 - 1.5e-24 85.7 0.0 1.8e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family Pkinase PF00069.20 KEG07179.1 - 2.4e-55 187.4 0.0 3.4e-55 186.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG07179.1 - 4e-18 65.4 0.0 5.1e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEG07179.1 - 0.00031 20.5 0.1 0.0039 16.9 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KEG07179.1 - 0.0026 16.8 0.0 0.0049 15.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KEG07179.1 - 0.067 12.7 0.1 0.16 11.5 0.0 1.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase Myb_DNA-bind_6 PF13921.1 KEG07181.1 - 8.2e-07 29.0 1.0 0.0025 17.8 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KEG07181.1 - 0.00014 21.8 1.1 0.65 10.0 0.1 2.8 2 1 0 2 2 2 2 Myb-like DNA-binding domain Secretin_N PF03958.12 KEG07181.1 - 0.091 12.9 2.3 0.85 9.8 0.5 2.5 2 1 0 2 2 2 0 Bacterial type II/III secretion system short domain Cgr1 PF03879.9 KEG07181.1 - 4.5 7.5 13.1 0.055 13.6 2.7 2.4 2 1 0 2 2 2 0 Cgr1 family YIF1 PF03878.10 KEG07182.1 - 4.1e-33 114.5 6.7 1.4e-32 112.7 4.7 1.7 1 1 0 1 1 1 1 YIF1 PRP38 PF03371.10 KEG07183.1 - 1.4e-20 73.6 0.0 1.9e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 PRP38 family PEX11 PF05648.9 KEG07188.1 - 1.6e-19 70.0 0.3 2.4e-19 69.4 0.2 1.2 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Peptidase_M8 PF01457.11 KEG07190.1 - 3e-104 349.2 5.8 2.6e-58 197.6 2.9 2.1 2 0 0 2 2 2 2 Leishmanolysin Reprolysin_5 PF13688.1 KEG07190.1 - 0.0062 16.4 0.1 0.0062 16.4 0.0 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KEG07190.1 - 0.24 11.9 0.0 0.24 11.9 0.0 2.1 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Herpes_capsid PF06112.6 KEG07190.1 - 7.8 6.5 11.9 17 5.4 8.2 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Monooxygenase_B PF04744.7 KEG07191.1 - 0.11 11.1 0.0 0.14 10.7 0.0 1.1 1 0 0 1 1 1 0 Monooxygenase subunit B protein TBPIP PF07106.8 KEG07193.1 - 0.02 14.4 0.4 0.02 14.4 0.3 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Snf7 PF03357.16 KEG07193.1 - 0.031 13.6 1.1 0.029 13.7 0.8 1.1 1 0 0 1 1 1 0 Snf7 GOLGA2L5 PF15070.1 KEG07193.1 - 0.043 12.3 1.9 0.046 12.2 1.3 1.0 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 Prefoldin_2 PF01920.15 KEG07193.1 - 0.046 13.4 1.0 0.066 12.9 0.7 1.2 1 0 0 1 1 1 0 Prefoldin subunit DUF1732 PF08340.6 KEG07193.1 - 0.062 13.1 0.0 0.076 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1732) TBCA PF02970.11 KEG07193.1 - 0.094 12.8 0.5 0.099 12.7 0.4 1.1 1 0 0 1 1 1 0 Tubulin binding cofactor A Spc24 PF08286.6 KEG07193.1 - 0.1 12.2 2.0 0.11 12.1 1.4 1.1 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 YlqD PF11068.3 KEG07193.1 - 0.12 12.4 3.1 0.12 12.3 2.2 1.1 1 0 0 1 1 1 0 YlqD protein Cast PF10174.4 KEG07193.1 - 0.25 9.3 4.3 0.27 9.2 3.0 1.0 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Prefoldin PF02996.12 KEG07193.1 - 0.61 9.7 2.8 0.71 9.5 1.9 1.1 1 0 0 1 1 1 0 Prefoldin subunit OmpH PF03938.9 KEG07193.1 - 0.68 9.8 6.2 0.72 9.7 4.3 1.0 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DivIC PF04977.10 KEG07193.1 - 1.4 8.4 3.8 1.8 8.1 2.7 1.2 1 0 0 1 1 1 0 Septum formation initiator FlxA PF14282.1 KEG07193.1 - 5.5 6.9 9.0 52 3.8 6.2 1.9 1 1 0 1 1 1 0 FlxA-like protein Tex_N PF09371.5 KEG07195.1 - 2.4e-42 144.4 0.8 3.6e-42 143.8 0.1 1.7 2 0 0 2 2 2 1 Tex-like protein N-terminal domain HHH_3 PF12836.2 KEG07195.1 - 4.1e-11 42.6 0.0 8.8e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 KEG07195.1 - 2.1e-06 27.3 0.1 6.5e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.1 KEG07195.1 - 0.00041 20.4 0.0 0.00085 19.4 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif S1 PF00575.18 KEG07195.1 - 0.00054 19.9 0.3 0.0011 18.9 0.2 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DUF655 PF04919.7 KEG07195.1 - 0.071 12.8 0.1 0.38 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF655) HHH PF00633.18 KEG07195.1 - 0.1 12.3 0.0 11 5.9 0.0 3.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif HHH_6 PF14579.1 KEG07195.1 - 0.11 12.5 0.5 1 9.4 0.0 2.8 4 0 0 4 4 4 0 Helix-hairpin-helix motif Latarcin PF10279.4 KEG07195.1 - 1.1 9.4 3.4 1.9 8.7 0.9 2.4 2 0 0 2 2 2 0 Latarcin precursor Tropomyosin PF00261.15 KEG07197.1 - 0.019 14.0 21.3 0.02 13.9 7.5 2.1 2 0 0 2 2 2 0 Tropomyosin Laminin_II PF06009.7 KEG07197.1 - 0.37 10.5 11.6 0.14 11.9 0.5 2.7 1 1 0 2 2 2 0 Laminin Domain II IncA PF04156.9 KEG07197.1 - 0.54 9.8 13.4 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 IncA protein MxiH PF09392.5 KEG07197.1 - 0.77 10.3 9.7 1.8e+02 2.7 6.7 3.1 1 1 0 1 1 1 0 Type III secretion needle MxiH like Flagellin_N PF00669.15 KEG07197.1 - 2.2 8.0 10.7 2.7 7.7 5.2 2.4 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region FlaC_arch PF05377.6 KEG07197.1 - 2.2 8.2 4.5 1.8 8.5 0.4 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) PEP-utilisers_N PF05524.8 KEG07197.1 - 2.7 7.8 17.3 0.34 10.6 0.6 2.5 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Atg14 PF10186.4 KEG07197.1 - 3.3 6.5 9.0 4.7 6.0 6.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Macoilin PF09726.4 KEG07197.1 - 4.8 5.3 11.5 6 5.0 8.0 1.2 1 0 0 1 1 1 0 Transmembrane protein Mucin PF01456.12 KEG07198.1 - 0.00023 20.9 6.8 0.013 15.2 4.7 2.3 1 1 0 1 1 1 1 Mucin-like glycoprotein Peptidase_C37 PF05416.7 KEG07198.1 - 0.028 12.7 0.2 0.048 11.9 0.1 1.4 1 0 0 1 1 1 0 Southampton virus-type processing peptidase DUF2514 PF10721.4 KEG07198.1 - 1.6 8.4 16.5 0.036 13.7 6.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) Acyl-CoA_dh_C PF12806.2 KEG07198.1 - 4 7.2 9.9 3.9 7.3 1.7 2.4 2 0 0 2 2 2 0 Acetyl-CoA dehydrogenase C-terminal like Mucin PF01456.12 KEG07200.1 - 0.00059 19.6 1.9 0.00079 19.2 1.3 1.3 1 1 0 1 1 1 1 Mucin-like glycoprotein DUF2514 PF10721.4 KEG07200.1 - 0.0082 15.8 3.5 0.016 14.9 2.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2514) Phage_GPL PF05926.6 KEG07200.1 - 0.024 14.4 0.7 0.044 13.6 0.5 1.4 1 0 0 1 1 1 0 Phage head completion protein (GPL) Mucin PF01456.12 KEG07202.1 - 0.32 10.7 13.2 0.42 10.3 9.1 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Neisseria_TspB PF05616.8 KEG07202.1 - 1.9 6.7 4.8 2.4 6.4 3.3 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein SOG2 PF10428.4 KEG07202.1 - 5.4 5.5 6.2 6.5 5.2 4.3 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Mucin PF01456.12 KEG07203.1 - 2.5e-05 24.0 61.1 0.034 13.9 16.7 3.7 2 2 0 2 2 2 2 Mucin-like glycoprotein Mucin PF01456.12 KEG07204.1 - 0.027 14.2 65.3 14 5.4 19.9 3.9 1 1 1 2 2 2 0 Mucin-like glycoprotein Mucin PF01456.12 KEG07205.1 - 0.022 14.5 45.5 0.014 15.2 23.0 3.4 2 1 0 2 2 2 0 Mucin-like glycoprotein DUF3568 PF12092.3 KEG07205.1 - 4.1 7.1 7.6 0.91 9.2 2.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3568) Oligomerisation PF02410.10 KEG07206.1 - 6.2e-15 55.0 0.6 1.4e-14 53.9 0.4 1.6 1 0 0 1 1 1 1 Oligomerisation domain Rho_Binding PF08912.6 KEG07207.1 - 0.0059 16.8 2.0 0.0059 16.8 1.4 2.8 3 0 0 3 3 2 1 Rho Binding Herpes_BLRF2 PF05812.7 KEG07207.1 - 0.026 14.3 3.1 0.026 14.3 2.2 2.9 3 0 0 3 3 3 0 Herpesvirus BLRF2 protein FlaC_arch PF05377.6 KEG07207.1 - 0.08 12.8 1.0 0.7 9.8 0.1 2.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) UPF0242 PF06785.6 KEG07207.1 - 0.26 9.9 5.6 0.92 8.1 0.5 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) DUF2730 PF10805.3 KEG07207.1 - 0.89 9.3 7.8 2 8.2 0.0 3.6 4 1 0 4 4 4 0 Protein of unknown function (DUF2730) HALZ PF02183.13 KEG07207.1 - 1.4 8.7 17.2 1.7 8.4 0.6 4.9 5 0 0 5 5 5 0 Homeobox associated leucine zipper DUF342 PF03961.8 KEG07207.1 - 2.3 6.5 6.6 0.84 7.9 2.5 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF342) CCDC-167 PF15188.1 KEG07207.1 - 5.3 7.0 9.7 3.4 7.6 2.5 3.3 3 1 0 3 3 3 0 Coiled-coil domain-containing protein 167 Mnd1 PF03962.10 KEG07207.1 - 6.3 6.4 12.3 0.16 11.5 1.3 2.7 2 1 1 3 3 3 0 Mnd1 family DUF2664 PF10867.3 KEG07207.1 - 6.6 7.4 11.1 8.3 7.1 1.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2664) DivIVA PF05103.8 KEG07207.1 - 6.9 6.7 12.2 3.7 7.6 1.0 3.7 3 1 0 3 3 3 0 DivIVA protein SlyX PF04102.7 KEG07207.1 - 9.7 6.6 13.0 32 4.9 0.0 4.2 4 0 0 4 4 4 0 SlyX zf-B_box PF00643.19 KEG07208.1 - 5.1e-05 23.0 1.0 0.00011 21.9 0.7 1.5 1 0 0 1 1 1 1 B-box zinc finger zf-Tim10_DDP PF02953.10 KEG07209.1 - 0.01 15.1 1.7 0.01 15.1 1.2 2.8 2 1 0 2 2 2 1 Tim10/DDP family zinc finger Git3_C PF11970.3 KEG07210.1 - 0.00076 19.1 2.0 0.003 17.3 1.4 2.0 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Ribosomal_S3_C PF00189.15 KEG07212.1 - 2.5e-16 59.6 1.1 4.2e-16 58.9 0.8 1.4 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 KEG07212.1 - 8.4e-10 38.0 0.0 2.3e-09 36.6 0.0 1.7 2 0 0 2 2 2 1 KH domain PP2C PF00481.16 KEG07213.1 - 0.0052 16.2 0.0 0.007 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Birna_VP5 PF03042.9 KEG07214.1 - 0.042 13.3 0.3 0.092 12.2 0.0 1.7 2 0 0 2 2 2 0 Birnavirus VP5 protein Galactosyl_T PF01762.16 KEG07215.1 - 4.8e-08 32.8 0.0 5.1e-05 22.9 0.0 3.5 3 1 0 3 3 3 1 Galactosyltransferase Galactosyl_T PF01762.16 KEG07217.1 - 0.0024 17.4 0.1 0.7 9.4 0.0 2.7 2 1 1 3 3 3 2 Galactosyltransferase DUF2360 PF10152.4 KEG07220.1 - 2.1 8.6 5.4 2.4 8.4 3.8 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF2076 PF09849.4 KEG07220.1 - 3.3 7.6 6.8 3.5 7.6 4.7 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Pkinase PF00069.20 KEG07221.1 - 2.6e-22 79.2 0.0 5.7e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG07221.1 - 4.9e-10 38.9 0.0 9.2e-10 38.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG07221.1 - 0.0014 17.6 0.0 0.0042 16.0 0.0 1.7 1 1 0 1 1 1 1 Kinase-like PUF PF00806.14 KEG07223.1 - 6.6e-37 122.9 1.8 4e-05 22.8 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat zf-C3HC4_3 PF13920.1 KEG07224.1 - 1.5e-11 43.7 10.9 2.7e-11 42.9 7.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Plus-3 PF03126.13 KEG07224.1 - 2.4e-07 30.7 0.0 4.7e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Plus-3 domain zf-C3HC4_2 PF13923.1 KEG07224.1 - 0.00099 19.0 12.9 0.0018 18.2 9.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEG07224.1 - 0.01 15.6 12.2 0.02 14.7 8.5 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 KEG07224.1 - 0.31 10.7 10.5 0.51 10.1 7.3 1.3 1 0 0 1 1 1 0 zinc-RING finger domain DSPn PF14671.1 KEG07225.1 - 5.9e-28 97.6 0.0 5.1e-18 65.4 0.0 3.2 4 0 0 4 4 4 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 KEG07225.1 - 5.9e-11 42.0 0.0 3.1e-10 39.7 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KEG07225.1 - 9.6e-05 21.8 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KEG07225.1 - 0.00099 19.1 0.0 0.0021 18.1 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Mucin PF01456.12 KEG07226.1 - 0.0098 15.6 11.0 0.011 15.4 7.7 1.1 1 0 0 1 1 1 1 Mucin-like glycoprotein Gastrin PF00918.12 KEG07226.1 - 0.31 11.8 1.5 0.37 11.6 1.1 1.1 1 0 0 1 1 1 0 Gastrin/cholecystokinin family RuBisCO_large_N PF02788.11 KEG07226.1 - 3.5 7.3 6.5 3 7.5 4.0 1.3 1 1 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain DUF3359 PF11839.3 KEG07226.1 - 5.1 7.4 19.1 6.1 7.2 13.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3359) Kelch_4 PF13418.1 KEG07227.1 - 0.0083 15.8 0.2 0.021 14.5 0.1 1.6 1 0 0 1 1 1 1 Galactose oxidase, central domain Mucin PF01456.12 KEG07228.1 - 0.00039 20.2 0.2 0.00039 20.2 0.1 3.0 2 1 0 2 2 2 1 Mucin-like glycoprotein Mucin PF01456.12 KEG07229.1 - 7.4e-05 22.5 29.1 0.026 14.2 8.8 3.2 2 2 0 2 2 2 2 Mucin-like glycoprotein Mit_KHE1 PF10173.4 KEG07229.1 - 0.018 14.8 1.0 0.033 14.0 0.7 1.4 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Clp_N PF02861.15 KEG07229.1 - 0.16 11.8 3.8 14 5.6 0.1 4.0 4 0 0 4 4 4 0 Clp amino terminal domain DUF4618 PF15397.1 KEG07229.1 - 0.25 10.6 6.9 1.7 7.8 4.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) Nucleoplasmin PF03066.10 KEG07230.1 - 0.044 13.3 0.4 0.054 12.9 0.3 1.1 1 0 0 1 1 1 0 Nucleoplasmin zf-CCCH PF00642.19 KEG07231.1 - 0.002 17.7 8.7 0.13 11.9 1.1 3.3 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LRV_FeS PF05484.6 KEG07231.1 - 4.4 6.9 5.8 10 5.7 0.0 2.9 3 0 0 3 3 3 0 LRV protein FeS4 cluster ALS_ss_C PF10369.4 KEG07232.1 - 0.035 13.8 0.1 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 Small subunit of acetolactate synthase DUF553 PF04473.7 KEG07232.1 - 0.089 12.0 0.3 0.11 11.7 0.2 1.2 1 0 0 1 1 1 0 Transglutaminase-like domain Daxx PF03344.10 KEG07233.1 - 0.00048 18.7 25.1 0.0006 18.4 17.4 1.2 1 0 0 1 1 1 1 Daxx Family CDC45 PF02724.9 KEG07233.1 - 0.081 10.9 29.0 0.12 10.3 20.1 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 KEG07233.1 - 0.13 11.4 30.1 0.18 11.0 20.9 1.1 1 0 0 1 1 1 0 SDA1 YL1 PF05764.8 KEG07233.1 - 0.25 10.9 34.2 0.29 10.6 23.7 1.0 1 0 0 1 1 1 0 YL1 nuclear protein Plasmodium_Vir PF05795.6 KEG07233.1 - 0.5 9.5 8.1 0.64 9.1 5.6 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Vfa1 PF08432.5 KEG07233.1 - 1.1 9.3 22.6 1.4 8.9 15.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TFIIF_alpha PF05793.7 KEG07233.1 - 1.6 7.0 30.7 2 6.6 21.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF572 PF04502.8 KEG07233.1 - 3.6 6.7 23.4 4.4 6.4 16.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4551 PF15087.1 KEG07233.1 - 6.7 4.9 8.7 7.8 4.7 6.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Tim54 PF11711.3 KEG07234.1 - 0.34 9.4 5.5 0.038 12.5 0.2 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Presenilin PF01080.12 KEG07234.1 - 1.3 7.7 3.1 8 5.1 1.7 2.1 2 0 0 2 2 2 0 Presenilin NYAP_C PF15452.1 KEG07235.1 - 0.032 13.2 1.0 0.032 13.2 0.7 1.1 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter Herpes_capsid PF06112.6 KEG07235.1 - 0.24 11.4 0.1 0.24 11.4 0.1 2.2 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Pkinase PF00069.20 KEG07236.1 - 5.7e-08 32.2 0.0 6.8e-08 31.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG07236.1 - 0.011 14.8 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 KEG07237.1 - 1.9e-13 50.1 0.0 3.3e-08 33.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.9 KEG07237.1 - 1.5e-05 24.1 0.0 2.6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 KEG07237.1 - 0.012 14.7 0.0 0.19 10.7 0.0 2.1 1 1 0 1 1 1 0 Protein tyrosine kinase A_deaminase PF00962.17 KEG07238.1 - 1.4e-06 27.4 0.0 0.00028 19.9 0.0 3.1 2 1 0 2 2 2 2 Adenosine/AMP deaminase FmrO PF07091.6 KEG07238.1 - 0.038 12.9 0.0 0.32 9.9 0.0 2.1 2 0 0 2 2 2 0 Ribosomal RNA methyltransferase (FmrO) CPSF_A PF03178.10 KEG07239.1 - 4.8e-15 55.4 0.0 1.1e-14 54.2 0.0 1.6 1 1 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.4 KEG07239.1 - 2.2e-07 29.4 0.0 0.0081 14.3 0.0 2.3 2 0 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term Ctf8 PF09696.5 KEG07240.1 - 5.5e-12 45.5 0.6 1.5e-10 40.8 0.6 2.5 2 1 0 2 2 2 1 Ctf8 Phostensin_N PF13916.1 KEG07240.1 - 2.8 7.9 8.7 2.1 8.3 0.7 2.3 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal APC_CDC26 PF10471.4 KEG07240.1 - 3.6 8.4 7.8 9.6 7.0 0.6 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Cmc1 PF08583.5 KEG07241.1 - 8.7e-05 22.2 5.3 8.7e-05 22.2 3.7 1.7 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.8 KEG07241.1 - 0.00035 19.9 3.7 0.0006 19.1 2.6 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cas_Cas1 PF01867.11 KEG07241.1 - 0.077 12.0 0.5 0.099 11.7 0.4 1.2 1 0 0 1 1 1 0 CRISPR associated protein Cas1 RNase_H PF00075.19 KEG07243.1 - 8e-07 29.4 0.0 1.1e-06 28.9 0.0 1.2 1 0 0 1 1 1 1 RNase H RVT_1 PF00078.22 KEG07245.1 - 0.025 13.9 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Amastin PF07344.6 KEG07248.1 - 1.5e-10 40.8 9.6 2.2e-10 40.3 6.6 1.3 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 KEG07248.1 - 0.00029 20.5 11.5 0.00029 20.5 8.0 2.0 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF998 PF06197.8 KEG07248.1 - 0.0084 15.4 11.6 0.037 13.3 5.7 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF998) DUF3278 PF11683.3 KEG07248.1 - 0.029 14.3 0.6 0.029 14.3 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) PalH PF08733.5 KEG07248.1 - 0.074 11.8 2.1 0.15 10.9 1.4 1.5 1 0 0 1 1 1 0 PalH/RIM21 PMP22_Claudin PF00822.15 KEG07248.1 - 0.087 12.4 14.3 0.21 11.2 9.9 1.8 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Ninjurin PF04923.7 KEG07248.1 - 0.17 11.5 19.7 3.3 7.4 4.4 3.2 2 1 0 3 3 3 0 Ninjurin KASH PF10541.4 KEG07248.1 - 0.32 10.8 0.1 0.32 10.8 0.1 3.1 4 0 0 4 4 4 0 Nuclear envelope localisation domain Cyto_ox_2 PF02322.10 KEG07248.1 - 0.5 9.4 12.7 0.92 8.6 8.8 1.5 1 1 0 1 1 1 0 Cytochrome oxidase subunit II PGM_PMM_I PF02878.11 KEG07249.1 - 3e-14 52.6 0.0 4.9e-08 32.5 0.0 2.4 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.15 KEG07249.1 - 7.7e-09 35.4 0.0 2.8e-08 33.6 0.0 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.11 KEG07249.1 - 9e-09 35.6 0.3 3.9e-08 33.5 0.1 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 KEG07249.1 - 0.0069 16.4 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III RRM_1 PF00076.17 KEG07250.1 - 1e-09 37.8 0.0 1.7e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG07250.1 - 1.9e-05 24.5 0.0 3.3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SR-25 PF10500.4 KEG07250.1 - 0.057 12.8 10.9 0.092 12.1 7.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Hepatitis_core PF00906.15 KEG07250.1 - 0.2 11.2 8.0 0.31 10.6 5.5 1.2 1 0 0 1 1 1 0 Hepatitis core antigen Ion_trans_2 PF07885.11 KEG07251.1 - 2.3e-10 40.0 2.5 2.3e-10 40.0 1.7 2.4 2 1 0 2 2 2 1 Ion channel zf-C2H2_jaz PF12171.3 KEG07252.1 - 0.0003 20.8 0.2 0.0012 18.8 0.0 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KEG07252.1 - 0.00035 20.3 1.2 0.002 17.9 0.4 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 KEG07252.1 - 0.0011 19.1 0.7 0.0011 19.1 0.5 2.9 3 0 0 3 3 3 1 Zinc finger, C2H2 type CpXC PF14353.1 KEG07252.1 - 0.0031 17.4 0.1 0.0067 16.3 0.1 1.5 1 0 0 1 1 1 1 CpXC protein zf-C2H2_4 PF13894.1 KEG07252.1 - 0.006 16.8 0.8 0.006 16.8 0.6 2.4 3 0 0 3 3 3 1 C2H2-type zinc finger Mto2_bdg PF12808.2 KEG07252.1 - 0.081 13.0 3.4 0.16 12.1 2.4 1.5 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region zf-H2C2_2 PF13465.1 KEG07252.1 - 0.09 13.1 0.8 0.09 13.1 0.6 2.7 3 0 0 3 3 3 0 Zinc-finger double domain SAE2 PF08573.5 KEG07252.1 - 0.33 11.6 3.5 0.7 10.6 2.4 1.5 1 0 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Trefoil PF00088.13 KEG07253.1 - 0.34 10.5 4.3 0.79 9.4 3.0 1.5 1 0 0 1 1 1 0 Trefoil (P-type) domain Involucrin_N PF10583.4 KEG07253.1 - 0.56 10.5 4.7 0.36 11.1 1.3 2.1 1 1 0 2 2 2 0 Involucrin of squamous epithelia N-terminus Pkinase PF00069.20 KEG07254.1 - 1e-60 205.1 0.0 1.3e-60 204.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG07254.1 - 5.7e-42 143.5 0.0 8.6e-42 142.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEG07254.1 - 0.0016 18.2 0.2 1.6 8.4 0.0 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 KEG07254.1 - 0.062 12.2 0.0 0.099 11.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 KEG07254.1 - 0.075 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Snf7 PF03357.16 KEG07255.1 - 8e-22 77.4 18.4 1.4e-21 76.6 12.7 1.5 1 1 0 1 1 1 1 Snf7 UME PF08064.8 KEG07255.1 - 0.36 10.8 2.6 0.19 11.6 0.2 1.8 2 1 0 2 2 2 0 UME (NUC010) domain Mer2 PF09074.5 KEG07255.1 - 3.6 7.4 12.2 4.4 7.1 7.4 1.8 1 1 1 2 2 2 0 Mer2 DUF59 PF01883.14 KEG07256.1 - 2.7e-05 24.0 0.0 0.0075 16.2 0.0 2.5 3 0 0 3 3 3 2 Domain of unknown function DUF59 TPR_12 PF13424.1 KEG07257.1 - 1.2e-06 28.3 6.8 0.13 12.1 0.2 3.9 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 KEG07257.1 - 0.00014 21.6 9.2 0.093 12.6 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 KEG07257.1 - 0.027 14.1 5.2 0.29 10.8 1.0 3.4 2 1 1 4 4 4 0 TPR repeat Kinesin PF00225.18 KEG07258.1 - 1.6e-14 53.3 1.1 1.6e-14 53.3 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain DUF4208 PF13907.1 KEG07258.1 - 0.075 13.2 2.9 0.17 12.1 2.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) Rgp1 PF08737.5 KEG07258.1 - 0.14 11.2 2.7 0.081 11.9 0.4 1.6 2 0 0 2 2 2 0 Rgp1 DivIVA PF05103.8 KEG07258.1 - 8.3 6.4 10.8 4.2 7.4 3.8 2.4 2 0 0 2 2 2 0 DivIVA protein Pkinase PF00069.20 KEG07260.1 - 6.3e-48 163.1 0.0 1.9e-47 161.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG07260.1 - 8.1e-18 64.4 0.0 3.9e-14 52.3 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 KEG07260.1 - 8.4e-07 28.2 0.0 1.3e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEG07260.1 - 0.00019 21.2 4.0 0.0011 18.8 0.0 2.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KEG07260.1 - 0.0068 15.4 0.0 0.022 13.8 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KEG07260.1 - 0.032 13.8 0.3 2.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pkinase PF00069.20 KEG07261.1 - 1.7e-57 194.5 0.0 3.6e-57 193.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG07261.1 - 1.9e-38 132.0 0.0 3.1e-38 131.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.24 KEG07261.1 - 1.2e-09 37.8 0.0 0.00017 21.3 0.0 3.0 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Kinase-like PF14531.1 KEG07261.1 - 1.3e-08 34.2 0.0 9.1e-08 31.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like PAS PF00989.19 KEG07261.1 - 4.3e-08 32.9 0.2 2.8e-07 30.3 0.0 2.5 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 KEG07261.1 - 6.4e-06 26.4 0.0 4.5e-05 23.7 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 KEG07261.1 - 0.0022 17.9 0.6 0.0064 16.5 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.1 KEG07261.1 - 0.034 14.0 0.1 0.36 10.7 0.0 2.6 2 0 0 2 2 2 0 PAS domain RHSP PF07999.6 KEG07263.1 - 1.7e-71 241.1 0.1 3.8e-60 203.7 0.0 2.3 2 0 0 2 2 2 2 Retrotransposon hot spot protein Macro_2 PF14519.1 KEG07263.1 - 0.0016 17.5 0.0 0.0028 16.8 0.0 1.3 1 0 0 1 1 1 1 Macro-like domain AAA_10 PF12846.2 KEG07263.1 - 0.012 15.0 0.1 0.16 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain Pap_E4 PF02711.9 KEG07263.1 - 2.3 9.0 8.0 0.58 11.0 2.9 2.0 2 0 0 2 2 2 0 E4 protein Nucleoplasmin PF03066.10 KEG07264.1 - 0.0033 16.9 4.3 0.0037 16.7 2.9 1.1 1 0 0 1 1 1 1 Nucleoplasmin DUF4611 PF15387.1 KEG07264.1 - 0.21 11.7 4.3 0.31 11.2 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) NOA36 PF06524.7 KEG07264.1 - 0.24 10.6 5.2 0.27 10.4 3.6 1.1 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.5 KEG07264.1 - 1.2 9.4 15.1 1.9 8.7 10.5 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RXT2_N PF08595.6 KEG07264.1 - 4.7 6.9 6.1 6.7 6.4 4.2 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Spt5_N PF11942.3 KEG07264.1 - 4.9 7.8 14.9 6.5 7.4 10.3 1.1 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal LRR_4 PF12799.2 KEG07265.1 - 1.4e-29 101.1 11.4 1.6e-05 24.4 0.1 11.6 10 2 6 16 16 16 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG07265.1 - 8.8e-16 57.4 25.1 0.011 15.4 0.1 8.8 6 3 5 11 11 11 8 Leucine rich repeat LRR_6 PF13516.1 KEG07265.1 - 2.2e-08 33.3 38.3 0.15 12.1 0.1 13.6 15 1 1 16 16 16 3 Leucine Rich repeat LRR_1 PF00560.28 KEG07265.1 - 3.1e-06 26.4 28.6 0.39 10.9 0.1 11.1 11 1 1 12 12 12 3 Leucine Rich Repeat LRR_7 PF13504.1 KEG07265.1 - 0.01 15.8 33.6 13 6.4 0.3 13.5 17 2 0 17 17 17 0 Leucine rich repeat LRR_9 PF14580.1 KEG07265.1 - 0.074 12.5 4.2 1.2 8.6 0.1 3.5 3 1 1 4 4 4 0 Leucine-rich repeat BT1 PF03092.11 KEG07266.1 - 4.7e-06 25.5 0.1 5.5e-06 25.3 0.0 1.0 1 0 0 1 1 1 1 BT1 family Fim-adh_lectin PF09222.5 KEG07266.1 - 0.075 12.3 0.0 0.096 11.9 0.0 1.1 1 0 0 1 1 1 0 Fimbrial adhesin F17-AG, lectin domain Sec63 PF02889.11 KEG07272.1 - 4.7e-42 144.3 0.0 2e-41 142.2 0.0 1.8 1 1 0 1 1 1 1 Sec63 Brl domain HHH_5 PF14520.1 KEG07272.1 - 4.2e-05 23.6 0.0 0.0001 22.3 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain Helicase_C PF00271.26 KEG07272.1 - 0.00012 21.8 0.0 0.00044 20.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DNA_pol_lambd_f PF10391.4 KEG07272.1 - 0.0043 16.5 0.0 0.011 15.2 0.0 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda Cdd1 PF11731.3 KEG07272.1 - 0.0051 16.7 0.0 0.015 15.2 0.0 1.8 1 0 0 1 1 1 1 Pathogenicity locus DUF4332 PF14229.1 KEG07272.1 - 0.02 14.8 0.0 0.35 10.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4332) Inhibitor_I29 PF08246.7 KEG07273.1 - 3.3e-11 43.2 0.0 4.5e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Glyco_transf_15 PF01793.11 KEG07274.1 - 1.7e-39 135.7 0.0 1.9e-39 135.5 0.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase WD40 PF00400.27 KEG07275.1 - 9.2e-05 22.1 0.4 0.0017 18.1 0.3 2.9 4 0 0 4 4 4 1 WD domain, G-beta repeat Keratin_matx PF04579.7 KEG07276.1 - 0.093 13.0 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Keratin, high-sulphur matrix protein c-SKI_SMAD_bind PF08782.5 KEG07276.1 - 0.11 12.6 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 c-SKI Smad4 binding domain UCH PF00443.24 KEG07277.1 - 7.6e-43 146.5 0.8 1.3e-42 145.7 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEG07277.1 - 9.5e-12 44.9 7.6 2.5e-10 40.3 1.9 3.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase PAT1 PF09770.4 KEG07277.1 - 9.5 4.3 17.3 16 3.5 12.0 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 WD40 PF00400.27 KEG07278.1 - 7.2e-06 25.6 1.9 0.21 11.5 0.0 4.4 3 1 0 3 3 3 2 WD domain, G-beta repeat Pkinase PF00069.20 KEG07279.1 - 9.4e-22 77.3 0.0 1.3e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG07279.1 - 2.6e-07 29.9 0.0 0.00059 18.9 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 KEG07279.1 - 0.0046 16.0 0.0 0.0066 15.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEG07279.1 - 0.036 13.7 0.1 0.12 12.1 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 KEG07279.1 - 0.078 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.1 KEG07279.1 - 0.17 10.8 0.0 0.32 9.9 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Phage_int_SAM_4 PF13495.1 KEG07280.1 - 0.048 13.9 0.1 0.067 13.5 0.1 1.1 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain BAF1_ABF1 PF04684.8 KEG07282.1 - 0.79 8.4 3.7 0.81 8.4 2.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Mucin PF01456.12 KEG07286.1 - 0.074 12.8 19.0 0.14 11.9 13.2 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein RNase_PH_C PF03725.10 KEG07287.1 - 0.003 17.4 0.0 0.0044 16.9 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF336 PF03928.9 KEG07287.1 - 0.14 11.9 4.3 0.21 11.4 2.7 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF336) HMG_box PF00505.14 KEG07290.1 - 1.2e-07 31.8 0.4 0.0052 17.0 0.3 3.9 3 1 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KEG07290.1 - 0.00023 21.4 1.2 0.0023 18.2 0.1 2.9 2 1 0 2 2 2 1 HMG-box domain Mucin PF01456.12 KEG07292.1 - 0.0022 17.7 13.1 0.0022 17.7 9.1 3.8 2 2 1 3 3 3 2 Mucin-like glycoprotein MCPsignal PF00015.16 KEG07293.1 - 2 7.8 37.0 0.015 14.8 10.2 3.2 1 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain ABC2_membrane_3 PF12698.2 KEG07295.1 - 1e-35 123.4 14.0 1e-35 123.4 9.7 1.4 2 0 0 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.2 KEG07295.1 - 0.0086 14.9 11.0 0.019 13.8 7.6 1.5 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF1049 PF06305.6 KEG07295.1 - 0.24 10.8 2.5 0.69 9.4 1.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) ABC_tran PF00005.22 KEG07296.1 - 2.9e-21 76.2 0.0 4.7e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KEG07296.1 - 3.2e-10 40.4 0.0 3.1e-07 30.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 KEG07296.1 - 0.0035 16.4 0.0 0.13 11.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain SRP54 PF00448.17 KEG07296.1 - 0.013 14.9 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_17 PF13207.1 KEG07296.1 - 0.11 13.3 0.0 0.27 12.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 KEG07296.1 - 0.14 12.3 0.2 0.34 11.0 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.14 KEG07296.1 - 0.17 11.0 0.0 1.9 7.6 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Dala_Dala_lig_N PF01820.16 KEG07297.1 - 0.08 13.2 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Defensin_beta PF00711.14 KEG07297.1 - 0.69 9.8 3.4 0.79 9.6 0.4 2.2 2 0 0 2 2 2 0 Beta defensin ABC2_membrane_3 PF12698.2 KEG07298.1 - 0.00014 21.0 0.1 0.0032 16.5 0.1 2.1 2 0 0 2 2 2 2 ABC-2 family transporter protein DUF3713 PF12506.3 KEG07299.1 - 0.016 15.3 0.7 0.016 15.3 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3713) PrgH PF09480.5 KEG07299.1 - 0.26 10.0 7.3 0.32 9.7 5.1 1.1 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) Pet20 PF08692.5 KEG07301.1 - 0.36 10.7 0.1 0.36 10.7 0.0 2.7 3 0 0 3 3 3 0 Mitochondrial protein Pet20 E1-N PF14463.1 KEG07303.1 - 0.025 14.2 0.1 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 E1 N-terminal domain KBP_C PF12309.3 KEG07306.1 - 0.11 11.4 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 KIF-1 binding protein C terminal N6-adenineMlase PF10237.4 KEG07307.1 - 1.3e-37 128.9 0.0 2.2e-37 128.1 0.0 1.4 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Methyltransf_26 PF13659.1 KEG07307.1 - 0.0042 17.1 1.6 0.0093 15.9 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Spectrin PF00435.16 KEG07307.1 - 0.025 14.8 0.4 0.025 14.8 0.3 3.4 3 0 0 3 3 3 0 Spectrin repeat Methyltransf_18 PF12847.2 KEG07307.1 - 0.13 12.8 1.0 1.7 9.2 0.0 3.1 3 1 0 4 4 4 0 Methyltransferase domain Mito_fiss_reg PF05308.6 KEG07310.1 - 0.27 10.5 7.4 4.3 6.6 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator HA2 PF04408.18 KEG07311.1 - 5.7e-16 58.3 0.6 2.5e-15 56.3 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KEG07311.1 - 1.2e-14 54.0 0.0 4.4e-14 52.2 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KEG07311.1 - 1e-09 38.1 0.0 4.4e-09 36.0 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEG07311.1 - 8.8e-07 28.5 0.0 2e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_23 PF13476.1 KEG07311.1 - 1.5e-05 25.3 2.5 0.051 13.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KEG07311.1 - 7.6e-05 22.8 0.2 0.00033 20.8 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEG07311.1 - 0.011 15.5 0.2 0.049 13.3 0.2 2.2 1 0 0 1 1 1 0 Part of AAA domain Zot PF05707.7 KEG07311.1 - 0.025 14.0 0.0 0.069 12.6 0.0 1.7 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) Flavi_DEAD PF07652.9 KEG07311.1 - 0.081 12.6 0.2 0.28 10.9 0.0 1.9 2 0 0 2 2 2 0 Flavivirus DEAD domain AAA_11 PF13086.1 KEG07311.1 - 0.94 8.9 8.0 4.7 6.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain V_ATPase_I PF01496.14 KEG07311.1 - 4.3 5.0 5.1 5.8 4.6 3.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF905 PF06006.7 KEG07314.1 - 0.054 12.8 0.7 6 6.3 0.1 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF905) SWI-SNF_Ssr4 PF08549.5 KEG07314.1 - 0.09 11.0 0.1 0.092 11.0 0.1 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) DUF3906 PF13046.1 KEG07318.1 - 0.14 11.7 1.8 0.36 10.4 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3906) DUF2228 PF10228.4 KEG07321.1 - 0.01 15.4 0.1 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) Limkain-b1 PF11608.3 KEG07321.1 - 0.14 11.9 0.4 0.43 10.3 0.2 1.8 2 0 0 2 2 2 0 Limkain b1 DBD_Tnp_Mut PF03108.10 KEG07322.1 - 0.045 13.3 0.0 0.16 11.5 0.0 2.0 1 0 0 1 1 1 0 MuDR family transposase DUF445 PF04286.7 KEG07322.1 - 0.056 12.9 0.5 0.084 12.3 0.1 1.6 2 1 0 2 2 2 0 Protein of unknown function (DUF445) DUF1469 PF07332.6 KEG07324.1 - 3.1 7.5 13.8 0.072 12.8 4.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1469) MRP-S28 PF10213.4 KEG07325.1 - 0.00083 19.4 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DUF3983 PF13137.1 KEG07326.1 - 0.16 11.7 1.1 0.33 10.6 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3983) NAC PF01849.13 KEG07327.1 - 3.9e-16 58.3 0.0 6.8e-16 57.5 0.0 1.4 1 0 0 1 1 1 1 NAC domain Tmemb_185A PF10269.4 KEG07329.1 - 5.7e-31 107.9 14.0 5.7e-31 107.9 9.7 1.6 2 0 0 2 2 2 1 Transmembrane Fragile-X-F protein DnaJ PF00226.26 KEG07329.1 - 3e-21 74.9 0.0 4.3e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Dapper PF15268.1 KEG07335.1 - 0.14 10.9 13.6 0.17 10.6 9.5 1.2 1 0 0 1 1 1 0 Dapper IncA PF04156.9 KEG07336.1 - 0.0021 17.6 4.2 0.0021 17.6 2.9 2.5 3 0 0 3 3 3 1 IncA protein ApoO PF09769.4 KEG07336.1 - 0.056 13.1 1.2 0.14 11.8 0.1 2.1 2 0 0 2 2 2 0 Apolipoprotein O Acyl-CoA_dh_1 PF00441.19 KEG07336.1 - 0.52 10.4 6.7 0.21 11.7 2.3 2.0 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain ATG_C PF09333.6 KEG07336.1 - 0.75 9.9 7.8 12 6.1 5.4 2.8 1 1 0 1 1 1 0 ATG C terminal domain Fib_alpha PF08702.5 KEG07336.1 - 1.3 9.1 5.1 5.2 7.1 0.1 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Tape_meas_lam_C PF09718.5 KEG07336.1 - 1.9 8.4 7.0 6.3 6.7 0.7 2.9 2 1 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Mucin PF01456.12 KEG07337.1 - 5.4e-06 26.2 0.8 0.00079 19.2 0.0 2.3 2 0 0 2 2 2 2 Mucin-like glycoprotein DUF2201_N PF13203.1 KEG07337.1 - 0.013 14.6 0.6 0.018 14.2 0.4 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF4398 PF14346.1 KEG07337.1 - 0.28 11.2 7.1 0.29 11.2 4.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4398) DUF3416 PF11896.3 KEG07337.1 - 0.53 10.2 3.7 1.8 8.4 1.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3416) LRR19-TM PF15176.1 KEG07339.1 - 4.9 6.9 5.2 9.7 5.9 0.1 2.8 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain DUF3665 PF12427.3 KEG07340.1 - 0.053 12.8 0.5 0.13 11.6 0.3 1.6 1 0 0 1 1 1 0 Branched-chain amino acid aminotransferase ABC_tran PF00005.22 KEG07341.1 - 2.2e-63 212.6 0.0 4.1e-25 88.6 0.0 3.3 2 1 1 3 3 3 3 ABC transporter ABC2_membrane_3 PF12698.2 KEG07341.1 - 7.6e-46 156.7 58.8 3.2e-38 131.6 14.8 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 KEG07341.1 - 4.6e-19 69.4 0.3 2.5e-05 24.3 0.0 5.2 4 1 0 4 4 4 3 AAA domain AAA_23 PF13476.1 KEG07341.1 - 3.2e-09 37.4 0.7 0.014 15.7 0.0 3.2 3 0 0 3 3 3 3 AAA domain AAA_29 PF13555.1 KEG07341.1 - 3.1e-08 33.0 0.7 0.017 14.6 0.0 3.6 3 0 0 3 3 3 2 P-loop containing region of AAA domain DUF258 PF03193.11 KEG07341.1 - 1.6e-06 27.4 0.3 0.0039 16.3 0.0 3.3 3 0 0 3 3 3 1 Protein of unknown function, DUF258 SRP54 PF00448.17 KEG07341.1 - 3.6e-06 26.5 3.1 0.0059 16.0 0.0 3.2 3 0 0 3 3 3 2 SRP54-type protein, GTPase domain SbcCD_C PF13558.1 KEG07341.1 - 5.2e-06 26.2 0.1 0.085 12.7 0.0 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 KEG07341.1 - 2.1e-05 23.7 0.2 1.3 8.0 0.1 3.8 4 0 0 4 4 4 1 Zeta toxin AAA_10 PF12846.2 KEG07341.1 - 2.4e-05 23.9 3.0 0.67 9.3 0.3 3.3 3 0 0 3 3 3 1 AAA-like domain SMC_N PF02463.14 KEG07341.1 - 3.3e-05 23.2 0.0 5.8 6.0 0.0 4.1 4 1 0 5 5 5 0 RecF/RecN/SMC N terminal domain MobB PF03205.9 KEG07341.1 - 0.00029 20.5 0.9 2 8.0 0.0 3.5 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 KEG07341.1 - 0.002 17.5 0.6 1.5 8.2 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.1 KEG07341.1 - 0.0037 16.3 0.0 2.6 6.9 0.0 3.7 4 0 0 4 4 4 1 AAA ATPase domain AAA_33 PF13671.1 KEG07341.1 - 0.005 16.7 0.4 8.5 6.2 0.1 3.4 3 0 0 3 3 3 0 AAA domain AAA_13 PF13166.1 KEG07341.1 - 0.0058 15.1 0.6 0.92 7.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain Miro PF08477.8 KEG07341.1 - 0.0073 16.7 0.1 13 6.2 0.0 3.3 3 0 0 3 3 3 0 Miro-like protein AAA_30 PF13604.1 KEG07341.1 - 0.0087 15.6 3.6 1 8.8 0.1 3.4 2 1 1 3 3 3 1 AAA domain UPF0079 PF02367.12 KEG07341.1 - 0.011 15.3 4.1 0.54 9.8 0.0 3.3 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 APS_kinase PF01583.15 KEG07341.1 - 0.015 14.9 0.1 7 6.2 0.0 3.3 2 1 1 3 3 3 0 Adenylylsulphate kinase MMR_HSR1 PF01926.18 KEG07341.1 - 0.018 15.0 0.0 8.6 6.3 0.0 3.3 3 0 0 3 3 3 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 KEG07341.1 - 0.026 14.6 2.9 13 5.9 0.1 3.6 3 0 0 3 3 3 0 RNA helicase AAA PF00004.24 KEG07341.1 - 0.032 14.4 3.2 2.9 8.1 0.0 3.7 3 1 1 4 4 3 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEG07341.1 - 0.051 13.5 0.1 8 6.3 0.0 3.2 3 1 0 3 3 3 0 AAA ATPase domain cobW PF02492.14 KEG07341.1 - 0.065 12.6 5.7 2.1 7.7 0.2 3.3 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 KEG07341.1 - 0.09 12.9 1.1 9.2 6.4 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 KEG07341.1 - 0.12 13.1 0.0 20 6.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain Thymidylate_kin PF02223.12 KEG07341.1 - 0.19 11.0 0.6 57 3.0 0.0 3.2 3 0 0 3 3 3 0 Thymidylate kinase TrwB_AAD_bind PF10412.4 KEG07341.1 - 0.3 9.6 1.8 16 4.0 0.0 2.9 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain AAA_28 PF13521.1 KEG07341.1 - 0.43 10.5 3.6 12 5.7 0.0 3.3 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.12 KEG07341.1 - 0.46 10.2 1.5 0.79 9.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 NACHT PF05729.7 KEG07341.1 - 0.69 9.5 7.0 1.6 8.3 0.0 3.9 4 0 0 4 4 3 0 NACHT domain FeoB_N PF02421.13 KEG07341.1 - 0.78 9.0 5.0 5.3 6.3 0.2 3.3 3 0 0 3 3 3 0 Ferrous iron transport protein B ATP_bind_1 PF03029.12 KEG07341.1 - 1 8.8 5.1 13 5.2 0.1 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein DLIC PF05783.6 KEG07341.1 - 1.6 7.3 2.5 4 5.9 0.1 2.2 2 1 1 3 3 3 0 Dynein light intermediate chain (DLIC) Fibrillarin PF01269.12 KEG07343.1 - 1e-101 338.6 0.0 1.1e-101 338.5 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 KEG07343.1 - 1.7e-07 31.0 0.0 2.2e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit DnaJ PF00226.26 KEG07344.1 - 0.0055 16.4 13.4 0.068 12.9 2.9 4.1 3 1 0 3 3 3 2 DnaJ domain EcsB PF05975.7 KEG07344.1 - 0.017 13.5 0.1 0.032 12.6 0.0 1.3 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB DnaJ PF00226.26 KEG07345.1 - 5.4e-19 67.6 1.7 8.7e-19 67.0 0.1 2.2 2 0 0 2 2 2 1 DnaJ domain SH3_9 PF14604.1 KEG07346.1 - 1.9e-07 30.5 0.1 3.2e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KEG07346.1 - 0.00025 20.3 0.0 0.00041 19.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain UPRTase PF14681.1 KEG07346.1 - 0.17 11.0 0.1 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Caldesmon PF02029.10 KEG07346.1 - 2 6.7 8.6 3.4 5.9 5.9 1.3 1 0 0 1 1 1 0 Caldesmon S-methyl_trans PF02574.11 KEG07347.1 - 3.3e-28 98.8 0.0 4.1e-21 75.5 0.0 4.0 3 1 0 3 3 3 3 Homocysteine S-methyltransferase DUF867 PF05908.6 KEG07347.1 - 0.14 11.1 0.0 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF867) Nsp1_C PF05064.8 KEG07348.1 - 0.068 12.8 2.0 0.14 11.8 1.4 1.4 1 0 0 1 1 1 0 Nsp1-like C-terminal region RRM_1 PF00076.17 KEG07349.1 - 8.5e-20 70.1 0.1 9.1e-15 54.0 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG07349.1 - 2.4e-14 53.0 0.0 1.4e-08 34.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG07349.1 - 4.5e-05 23.2 0.0 0.04 13.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CRAL_TRIO PF00650.15 KEG07350.1 - 1e-30 106.3 0.0 1.5e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain UCH PF00443.24 KEG07351.1 - 2e-29 102.5 0.0 3.6e-29 101.7 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEG07351.1 - 2.6e-18 66.4 0.0 4.4e-18 65.7 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PHTB1_N PF14727.1 KEG07352.1 - 2.2e-118 395.8 0.0 3.2e-118 395.3 0.0 1.1 1 0 0 1 1 1 1 PTHB1 N-terminus PHTB1_C PF14728.1 KEG07352.1 - 2.9e-60 204.0 0.0 4e-60 203.6 0.0 1.1 1 0 0 1 1 1 1 PTHB1 C-terminus Nodulin_late PF07127.6 KEG07353.1 - 0.035 14.2 2.3 0.041 14.0 0.0 2.1 2 0 0 2 2 2 0 Late nodulin protein Peptidase_M8 PF01457.11 KEG07354.1 - 1.2e-110 370.3 10.8 2e-62 211.2 3.2 2.1 2 0 0 2 2 2 2 Leishmanolysin Peptidase_M57 PF12388.3 KEG07354.1 - 0.032 13.5 2.9 0.047 13.0 0.1 2.3 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase zf-MIZ PF02891.15 KEG07354.1 - 0.034 13.6 0.1 0.28 10.7 0.0 2.4 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger PMAIP1 PF15150.1 KEG07355.1 - 2 8.2 4.2 0.61 9.8 0.4 1.9 2 0 0 2 2 2 0 Phorbol-12-myristate-13-acetate-induced MACPF PF01823.14 KEG07357.1 - 0.046 13.4 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 MAC/Perforin domain PI3K_C2 PF00792.19 KEG07359.1 - 0.032 14.0 0.0 0.069 12.9 0.0 1.5 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 ASCH PF04266.9 KEG07360.1 - 2.8e-14 53.3 0.0 6.9e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 ASCH domain zf-C2HC5 PF06221.8 KEG07360.1 - 8.8e-12 44.5 8.2 1.7e-11 43.7 5.7 1.5 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type His_Phos_1 PF00300.17 KEG07361.1 - 2.2e-32 112.3 0.0 2.5e-32 112.1 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Adaptin_binding PF10199.4 KEG07362.1 - 0.059 13.6 2.5 0.091 13.0 1.7 1.3 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DUF3827 PF12877.2 KEG07362.1 - 0.18 9.8 1.3 0.23 9.5 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF4407 PF14362.1 KEG07362.1 - 0.49 9.2 4.9 0.7 8.7 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Synaptobrevin PF00957.16 KEG07363.1 - 4.1e-31 106.4 4.0 6.7e-31 105.7 2.7 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 KEG07363.1 - 0.0004 19.8 0.0 0.00089 18.7 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain EMP24_GP25L PF01105.19 KEG07363.1 - 0.0031 17.2 0.0 0.0047 16.6 0.0 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Mucin PF01456.12 KEG07364.1 - 0.00062 19.5 2.5 0.00062 19.5 1.7 3.7 2 1 0 2 2 2 1 Mucin-like glycoprotein Mucin PF01456.12 KEG07365.1 - 0.0029 17.3 22.4 0.015 15.1 5.9 2.6 2 1 0 2 2 2 2 Mucin-like glycoprotein Hydrolase_6 PF13344.1 KEG07365.1 - 0.043 13.7 2.9 2.3 8.1 0.1 2.7 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Ferritin PF00210.19 KEG07365.1 - 0.88 9.3 4.8 0.76 9.5 0.2 2.3 2 1 1 3 3 3 0 Ferritin-like domain Spc7 PF08317.6 KEG07367.1 - 2.7e-05 23.0 9.1 2.7e-05 23.0 6.3 7.7 2 2 5 8 8 8 6 Spc7 kinetochore protein Baculo_PEP_C PF04513.7 KEG07367.1 - 3.8e-05 23.5 38.2 0.085 12.6 1.5 9.5 6 2 4 10 10 10 4 Baculovirus polyhedron envelope protein, PEP, C terminus LPP PF04728.8 KEG07367.1 - 0.00048 19.8 5.5 3.1 7.6 0.2 5.4 5 0 0 5 5 5 2 Lipoprotein leucine-zipper Reo_sigmaC PF04582.7 KEG07367.1 - 0.01 15.0 45.5 0.1 11.7 0.8 7.7 3 3 6 9 9 9 0 Reovirus sigma C capsid protein Laminin_II PF06009.7 KEG07367.1 - 0.013 15.2 0.4 0.013 15.2 0.3 9.8 5 3 5 11 11 11 0 Laminin Domain II NPV_P10 PF05531.7 KEG07367.1 - 0.87 9.8 35.1 0.51 10.6 0.6 9.8 6 4 2 10 10 10 0 Nucleopolyhedrovirus P10 protein Abhydrolase_6 PF12697.2 KEG07368.1 - 0.0053 16.6 0.0 0.0085 15.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEG07368.1 - 0.012 15.3 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.15 KEG07368.1 - 0.017 14.5 0.1 0.12 11.8 0.0 2.1 2 0 0 2 2 2 0 Putative esterase CN_hydrolase PF00795.17 KEG07369.1 - 1.7e-30 105.8 0.0 2.2e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Arf PF00025.16 KEG07371.1 - 1.6e-48 164.2 0.0 1.9e-48 164.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KEG07371.1 - 9.2e-13 47.8 0.0 1.1e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KEG07371.1 - 9.3e-10 38.4 0.0 1.3e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 KEG07371.1 - 4.3e-09 35.5 1.4 6.2e-06 25.1 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 KEG07371.1 - 2.6e-08 33.3 0.0 3.6e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEG07371.1 - 4e-07 30.5 0.0 1e-06 29.2 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KEG07371.1 - 4.7e-06 26.1 0.2 0.00029 20.3 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KEG07371.1 - 9.5e-05 21.6 0.0 0.00012 21.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 KEG07371.1 - 0.0022 17.2 0.3 0.0066 15.7 0.1 1.9 2 1 0 2 2 2 1 Ferrous iron transport protein B AAA_18 PF13238.1 KEG07371.1 - 0.068 13.4 0.0 0.091 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 KEG07371.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 KEG07371.1 - 0.14 11.5 0.2 2.9 7.3 0.0 2.2 1 1 1 2 2 2 0 FtsK/SpoIIIE family LSM PF01423.17 KEG07372.1 - 0.021 14.3 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 LSM domain DUF490 PF04357.8 KEG07372.1 - 0.089 11.8 0.0 0.1 11.6 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF490) Amidase PF01425.16 KEG07373.1 - 2.3e-62 211.2 0.0 1.4e-61 208.7 0.0 1.9 1 1 0 1 1 1 1 Amidase RCC1_2 PF13540.1 KEG07374.1 - 1.6e-11 43.4 5.5 0.00031 20.2 0.2 3.7 3 1 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 KEG07374.1 - 8.5e-08 32.2 16.2 0.046 13.9 0.2 6.2 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat EMP24_GP25L PF01105.19 KEG07375.1 - 1.8e-28 99.4 0.0 2.7e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD COPIIcoated_ERV PF07970.7 KEG07376.1 - 8e-67 225.0 0.0 1.8e-66 223.9 0.0 1.6 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KEG07376.1 - 8.1e-26 89.8 0.1 1.6e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Vac_Fusion PF02346.11 KEG07377.1 - 0.022 14.1 0.7 0.099 12.0 0.2 2.2 1 1 1 2 2 2 0 Chordopoxvirus fusion protein DUF972 PF06156.8 KEG07377.1 - 0.026 14.8 8.1 0.87 9.9 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) O-FucT PF10250.4 KEG07380.1 - 0.15 11.0 0.1 0.43 9.6 0.0 1.7 2 0 0 2 2 2 0 GDP-fucose protein O-fucosyltransferase TIMELESS_C PF05029.8 KEG07381.1 - 0.19 10.5 10.6 0.22 10.3 7.4 1.0 1 0 0 1 1 1 0 Timeless protein C terminal region BUD22 PF09073.5 KEG07381.1 - 0.4 9.7 10.5 0.45 9.5 7.3 1.1 1 0 0 1 1 1 0 BUD22 DUF3245 PF11595.3 KEG07381.1 - 0.79 9.9 8.8 0.85 9.8 1.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3245) SPT2 PF08243.6 KEG07381.1 - 7.2 6.9 13.6 6.8 7.0 8.1 1.9 1 1 0 1 1 1 0 SPT2 chromatin protein Exo_endo_phos_2 PF14529.1 KEG07382.1 - 7.1e-07 28.8 0.0 8.1e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.22 KEG07383.1 - 3.6e-28 98.3 0.0 5.1e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DCR PF14047.1 KEG07384.1 - 0.068 13.4 0.8 8.5 6.7 0.1 2.4 2 0 0 2 2 2 0 Dppa2/4 conserved region RhoGAP PF00620.22 KEG07385.1 - 0.015 14.9 0.2 0.042 13.4 0.1 1.8 2 0 0 2 2 2 0 RhoGAP domain Ribosomal_L10 PF00466.15 KEG07387.1 - 1.8e-24 85.5 0.1 3.1e-24 84.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 KEG07387.1 - 1e-15 57.9 8.3 2.3e-15 56.7 5.7 1.7 1 0 0 1 1 1 1 60s Acidic ribosomal protein Pkinase PF00069.20 KEG07388.1 - 2.6e-56 190.6 0.0 3.9e-56 190.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG07388.1 - 2.3e-37 128.4 0.0 5.3e-37 127.3 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KEG07388.1 - 9.5e-05 22.2 0.0 0.00069 19.4 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KEG07388.1 - 0.0003 20.2 0.0 0.00052 19.4 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 KEG07388.1 - 0.00061 18.8 0.0 0.0012 17.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KEG07388.1 - 0.0062 15.3 0.2 0.013 14.3 0.1 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.9 KEG07388.1 - 0.0097 14.9 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Nucleoplasmin PF03066.10 KEG07388.1 - 0.092 12.2 2.8 0.19 11.2 2.0 1.5 1 0 0 1 1 1 0 Nucleoplasmin LEAP-2 PF07359.6 KEG07388.1 - 0.13 11.9 0.1 0.33 10.6 0.1 1.6 1 0 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) DUF3245 PF11595.3 KEG07388.1 - 6.6 6.9 8.5 5.6 7.2 2.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) LicD PF04991.8 KEG07389.1 - 5.8e-07 29.8 0.2 0.00089 19.4 0.2 2.2 2 0 0 2 2 2 2 LicD family Ycf1 PF05758.7 KEG07390.1 - 0.6 7.7 10.7 0.68 7.5 7.4 1.1 1 0 0 1 1 1 0 Ycf1 PMSI1 PF15322.1 KEG07390.1 - 3 6.8 14.1 0.36 9.8 6.7 1.5 2 0 0 2 2 2 0 Protein missing in infertile sperm 1, putative WW PF00397.21 KEG07391.1 - 1.3e-06 28.1 0.3 2.6e-06 27.1 0.2 1.5 1 0 0 1 1 1 1 WW domain GAS PF13851.1 KEG07393.1 - 0.0048 16.1 4.3 0.0048 16.1 3.0 7.2 5 2 2 7 7 7 3 Growth-arrest specific micro-tubule binding DUF1561 PF07598.6 KEG07393.1 - 0.18 9.7 0.4 0.28 9.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1561) bZIP_1 PF00170.16 KEG07393.1 - 0.49 10.3 0.1 0.49 10.3 0.0 9.3 8 3 3 11 11 11 0 bZIP transcription factor zf-RING_UBOX PF13445.1 KEG07396.1 - 0.00062 19.4 0.8 0.0014 18.3 0.0 2.0 2 0 0 2 2 2 1 RING-type zinc-finger Nodulin-like PF06813.8 KEG07399.1 - 1.1e-16 60.9 16.1 1.3e-15 57.3 11.1 2.4 1 1 0 1 1 1 1 Nodulin-like MFS_1 PF07690.11 KEG07399.1 - 3.6e-16 58.8 23.6 3.6e-16 58.8 16.4 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3767 PF12597.3 KEG07399.1 - 0.14 11.8 0.6 0.47 10.1 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) DUF1129 PF06570.6 KEG07399.1 - 0.88 8.8 3.5 3.5 6.8 1.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) LRR_6 PF13516.1 KEG07400.1 - 0.00018 21.2 0.0 0.08 13.0 0.1 3.1 2 0 0 2 2 2 2 Leucine Rich repeat LRR_8 PF13855.1 KEG07400.1 - 0.024 14.3 0.2 3.2 7.5 0.1 3.2 3 0 0 3 3 3 0 Leucine rich repeat UPF0564 PF10595.4 KEG07401.1 - 0.00059 18.8 19.6 0.00059 18.8 13.6 3.4 2 2 1 3 3 3 1 Uncharacterised protein family UPF0564 Mrr_cat PF04471.7 KEG07403.1 - 0.15 11.8 0.3 0.18 11.5 0.2 1.1 1 0 0 1 1 1 0 Restriction endonuclease PPTA PF01239.17 KEG07405.1 - 1.2e-06 27.5 7.4 0.00028 20.0 0.5 3.1 3 0 0 3 3 3 2 Protein prenyltransferase alpha subunit repeat PSCyt2 PF07583.6 KEG07405.1 - 0.069 12.6 1.5 1.1 8.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1549) ORC6 PF05460.8 KEG07406.1 - 1.4 7.9 5.8 1.7 7.6 4.0 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) MobB PF03205.9 KEG07407.1 - 2e-06 27.5 0.0 4e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Clp1 PF06807.9 KEG07407.1 - 5.8e-05 22.9 0.2 0.00019 21.2 0.1 1.8 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 AAA_33 PF13671.1 KEG07407.1 - 0.0031 17.3 0.1 0.019 14.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEG07407.1 - 0.006 16.5 0.2 0.02 14.9 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.22 KEG07407.1 - 0.01 16.1 0.1 0.11 12.8 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_10 PF12846.2 KEG07407.1 - 0.018 14.5 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain NACHT PF05729.7 KEG07407.1 - 0.019 14.6 0.2 0.041 13.5 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.1 KEG07407.1 - 0.029 15.1 0.1 0.091 13.5 0.0 1.9 2 0 0 2 2 1 0 AAA domain DUF258 PF03193.11 KEG07407.1 - 0.078 12.1 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 KEG07407.1 - 0.079 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 KEG07407.1 - 0.09 12.9 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KEG07407.1 - 0.17 11.4 0.0 0.43 10.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF812 PF05667.6 KEG07410.1 - 0.00093 17.8 4.1 0.0013 17.3 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) ASD2 PF08687.6 KEG07410.1 - 0.0055 16.0 1.7 0.0073 15.6 1.2 1.1 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 V_ATPase_I PF01496.14 KEG07410.1 - 0.0077 14.1 1.3 0.0088 13.9 0.9 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Prefoldin_2 PF01920.15 KEG07410.1 - 0.011 15.5 4.1 0.011 15.5 2.9 1.8 1 1 0 1 1 1 0 Prefoldin subunit EMP24_GP25L PF01105.19 KEG07410.1 - 0.012 15.3 1.9 0.022 14.4 1.3 1.4 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD HOOK PF05622.7 KEG07410.1 - 0.013 13.3 6.4 0.02 12.7 4.4 1.2 1 0 0 1 1 1 0 HOOK protein Atg14 PF10186.4 KEG07410.1 - 0.02 13.8 7.4 0.03 13.2 5.1 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Herpes_UL6 PF01763.11 KEG07410.1 - 0.035 12.2 4.4 0.046 11.9 3.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF342 PF03961.8 KEG07410.1 - 0.066 11.6 5.0 0.09 11.1 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Prominin PF05478.6 KEG07410.1 - 0.13 9.7 1.7 0.15 9.5 1.2 1.0 1 0 0 1 1 1 0 Prominin CHD5 PF04420.9 KEG07410.1 - 0.13 11.8 5.5 0.21 11.2 3.8 1.3 1 0 0 1 1 1 0 CHD5-like protein DUF948 PF06103.6 KEG07410.1 - 0.13 12.0 1.7 0.24 11.3 1.2 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) AKNA PF12443.3 KEG07410.1 - 0.14 12.1 5.4 0.27 11.2 3.7 1.4 1 0 0 1 1 1 0 AT-hook-containing transcription factor Tho2 PF11262.3 KEG07410.1 - 0.15 11.0 8.1 0.22 10.5 5.6 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF3450 PF11932.3 KEG07410.1 - 0.31 10.2 9.7 0.52 9.5 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF848 PF05852.6 KEG07410.1 - 0.39 10.5 5.1 0.58 9.9 3.5 1.2 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DUF3154 PF11351.3 KEG07410.1 - 0.9 9.2 3.8 0.89 9.3 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3154) DUF972 PF06156.8 KEG07410.1 - 0.95 9.8 7.2 1.9 8.8 4.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF972) TMPIT PF07851.8 KEG07410.1 - 1.5 7.8 5.5 1.9 7.4 3.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein Spc7 PF08317.6 KEG07410.1 - 1.5 7.3 10.6 2.3 6.8 7.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF724 PF05266.9 KEG07410.1 - 1.7 8.1 8.1 2.9 7.4 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Cortex-I_coil PF09304.5 KEG07410.1 - 1.8 8.6 9.6 17 5.4 6.5 2.1 1 1 1 2 2 2 0 Cortexillin I, coiled coil bZIP_2 PF07716.10 KEG07410.1 - 5.8 6.8 9.9 1.1 9.1 2.2 2.5 2 0 0 2 2 2 0 Basic region leucine zipper YlqD PF11068.3 KEG07410.1 - 6.3 6.8 12.3 11 6.0 8.5 1.4 1 0 0 1 1 1 0 YlqD protein OmpH PF03938.9 KEG07410.1 - 7.9 6.4 13.5 13 5.6 9.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Exo_endo_phos_2 PF14529.1 KEG07412.1 - 2.3e-13 49.7 0.0 2.8e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.22 KEG07413.1 - 0.0051 16.1 0.0 0.0071 15.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 KEG07414.1 - 5.3e-15 55.3 0.0 7e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) VanW PF04294.8 KEG07414.1 - 0.043 13.0 0.0 0.088 12.0 0.0 1.4 2 0 0 2 2 2 0 VanW like protein RVT_1 PF00078.22 KEG07415.1 - 5.9e-06 25.7 0.0 1.3e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-Di19 PF05605.7 KEG07416.1 - 0.65 10.1 4.4 0.53 10.4 0.9 2.4 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Pex24p PF06398.6 KEG07418.1 - 2.2e-06 26.7 0.1 2.3e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin BAF1_ABF1 PF04684.8 KEG07418.1 - 2 7.1 9.5 2.5 6.8 6.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SH3BGR PF04908.10 KEG07419.1 - 2.2e-10 40.3 0.3 1.2e-09 37.9 0.0 2.2 2 1 0 2 2 2 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.19 KEG07419.1 - 0.00023 21.0 0.0 0.0012 18.7 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin Transaldolase PF00923.14 KEG07420.1 - 1.8e-10 40.4 0.0 2.1e-10 40.2 0.0 1.0 1 0 0 1 1 1 1 Transaldolase Peptidase_M8 PF01457.11 KEG07421.1 - 8.3e-117 390.6 5.7 1e-116 390.3 3.9 1.0 1 0 0 1 1 1 1 Leishmanolysin Flavodoxin_4 PF12682.2 KEG07421.1 - 0.032 13.5 0.1 3.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Flavodoxin Bunya_RdRp PF04196.7 KEG07422.1 - 0.023 12.7 2.6 0.03 12.3 1.8 1.1 1 0 0 1 1 1 0 Bunyavirus RNA dependent RNA polymerase Mucin PF01456.12 KEG07422.1 - 0.071 12.8 29.5 0.9 9.3 7.0 2.9 2 1 0 2 2 2 0 Mucin-like glycoprotein NigD PF12667.2 KEG07422.1 - 0.091 12.5 2.2 0.067 12.9 0.4 1.6 2 0 0 2 2 2 0 NigD-like protein PI-PLC-X PF00388.14 KEG07424.1 - 0.02 14.3 0.0 0.021 14.1 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Amastin PF07344.6 KEG07425.1 - 5.7e-09 35.7 9.2 7.9e-09 35.3 6.4 1.3 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 KEG07425.1 - 0.42 10.2 13.6 0.041 13.5 5.6 1.8 1 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction SUR7 PF06687.7 KEG07425.1 - 0.82 9.1 11.0 0.06 12.9 4.3 1.6 2 0 0 2 2 2 0 SUR7/PalI family Yip1 PF04893.12 KEG07425.1 - 0.97 8.9 12.4 14 5.1 8.6 2.2 1 1 0 1 1 1 0 Yip1 domain Colicin_V PF02674.11 KEG07425.1 - 3.3 7.5 12.8 0.27 11.0 4.5 2.2 2 1 0 2 2 2 0 Colicin V production protein V_ATPase_I PF01496.14 KEG07426.1 - 0.53 8.0 6.6 1.5 6.5 0.3 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family IncA PF04156.9 KEG07430.1 - 0.0016 18.0 0.0 0.002 17.7 0.0 1.1 1 0 0 1 1 1 1 IncA protein DUF1191 PF06697.7 KEG07430.1 - 0.0035 16.1 0.1 0.0046 15.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) P12 PF12669.2 KEG07430.1 - 0.01 16.0 0.1 0.017 15.3 0.1 1.3 1 0 0 1 1 1 0 Virus attachment protein p12 family EphA2_TM PF14575.1 KEG07430.1 - 0.011 16.0 0.0 0.019 15.3 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain S1FA PF04689.8 KEG07430.1 - 0.013 15.3 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 DNA binding protein S1FA Sensor PF13796.1 KEG07430.1 - 0.014 14.9 2.0 0.014 14.9 0.6 1.6 2 0 0 2 2 2 0 Putative sensor Rifin_STEVOR PF02009.11 KEG07430.1 - 0.035 13.7 0.0 0.045 13.3 0.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family VSP PF03302.8 KEG07430.1 - 0.057 12.0 0.9 0.092 11.3 0.1 1.7 2 0 0 2 2 2 0 Giardia variant-specific surface protein TrbL PF04610.9 KEG07430.1 - 0.063 12.9 0.2 0.083 12.5 0.1 1.1 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein DNA_pol_A_exo1 PF01612.15 KEG07432.1 - 1.6e-11 43.9 0.0 2.9e-10 39.9 0.0 2.2 2 0 0 2 2 2 1 3'-5' exonuclease MORN PF02493.15 KEG07433.1 - 1.1e-27 94.0 44.7 7.8e-06 25.3 0.9 7.6 7 0 0 7 7 7 7 MORN repeat Kinesin PF00225.18 KEG07433.1 - 9.8e-21 73.8 0.0 7.1e-20 70.9 0.0 2.4 1 1 0 1 1 1 1 Kinesin motor domain Lebercilin PF15619.1 KEG07433.1 - 0.0028 17.0 21.2 0.0028 17.0 14.7 3.6 2 1 0 3 3 3 1 Ciliary protein causing Leber congenital amaurosis disease Bap31 PF05529.7 KEG07434.1 - 0.0018 17.7 1.9 0.0031 17.0 1.3 1.5 1 1 0 1 1 1 1 B-cell receptor-associated protein 31-like DSBA PF01323.15 KEG07435.1 - 0.041 13.4 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Sep15_SelM PF08806.6 KEG07435.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Sep15/SelM redox domain FKS1_dom1 PF14288.1 KEG07435.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 1,3-beta-glucan synthase subunit FKS1, domain-1 Proteasome PF00227.21 KEG07436.1 - 1.8e-49 167.6 0.0 2.3e-49 167.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KEG07436.1 - 8.3e-13 47.3 0.5 1.4e-12 46.6 0.3 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature AA_permease_2 PF13520.1 KEG07437.1 - 2.5e-33 115.2 39.1 3.2e-33 114.9 27.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KEG07437.1 - 1.6e-11 43.2 33.2 3.1e-11 42.3 22.9 1.4 1 1 0 1 1 1 1 Amino acid permease Galactosyl_T PF01762.16 KEG07439.1 - 0.026 14.1 0.2 0.22 11.0 0.0 2.5 2 1 1 3 3 3 0 Galactosyltransferase SET PF00856.23 KEG07441.1 - 9.7e-13 48.7 0.0 6.8e-11 42.7 0.0 2.6 2 1 0 2 2 2 1 SET domain SAF PF08666.7 KEG07441.1 - 0.071 13.5 0.0 2 8.8 0.0 2.4 2 0 0 2 2 2 0 SAF domain Streptin-Immun PF11083.3 KEG07443.1 - 0.00072 19.4 13.3 0.054 13.4 0.2 4.2 3 1 1 4 4 4 3 Lantibiotic streptin immunity protein DASH_Dam1 PF08653.5 KEG07443.1 - 1.1 9.0 7.5 5.5 6.8 0.4 3.5 3 0 0 3 3 3 0 DASH complex subunit Dam1 DUF948 PF06103.6 KEG07443.1 - 3.6 7.4 6.6 4.5 7.2 0.2 3.6 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) AChE_tetra PF08674.5 KEG07444.1 - 0.19 11.2 1.0 0.36 10.3 0.7 1.5 1 0 0 1 1 1 0 Acetylcholinesterase tetramerisation domain AAA_23 PF13476.1 KEG07445.1 - 0.02 15.2 19.6 0.013 15.7 7.5 3.2 3 0 0 3 3 3 0 AAA domain AlkA_N PF06029.6 KEG07445.1 - 0.039 14.0 0.2 0.34 10.9 0.0 2.4 2 0 0 2 2 2 0 AlkA N-terminal domain USP8_interact PF08941.5 KEG07445.1 - 0.045 13.0 0.3 0.045 13.0 0.2 4.5 5 0 0 5 5 5 0 USP8 interacting Proteasome_A_N PF10584.4 KEG07445.1 - 0.063 12.6 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature Peptidase_S28 PF05577.7 KEG07445.1 - 0.087 11.3 6.0 0.16 10.5 4.2 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 ATG16 PF08614.6 KEG07445.1 - 0.16 11.7 49.5 1.7 8.3 0.1 5.3 4 1 1 5 5 5 0 Autophagy protein 16 (ATG16) CENP-Q PF13094.1 KEG07445.1 - 0.37 10.8 42.7 1.4 8.9 6.1 5.6 3 1 2 5 5 5 0 CENP-Q, a CENPA-CAD centromere complex subunit GAS PF13851.1 KEG07445.1 - 0.84 8.7 48.8 0.45 9.6 8.8 5.0 4 1 1 5 5 5 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 KEG07445.1 - 1.6 8.6 48.9 1.5 8.6 4.8 5.2 4 1 1 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 KEG07445.1 - 3.6 6.6 13.7 1.4 8.0 0.9 4.5 3 1 2 5 5 5 0 Reovirus sigma C capsid protein Mod_r PF07200.8 KEG07445.1 - 4.4 7.2 40.2 0.19 11.6 1.7 4.9 5 0 0 5 5 5 0 Modifier of rudimentary (Mod(r)) protein LOH1CR12 PF10158.4 KEG07445.1 - 4.4 7.0 16.0 2.7 7.7 4.7 3.3 3 0 0 3 3 3 0 Tumour suppressor protein DUF4326 PF14216.1 KEG07445.1 - 4.6 7.8 7.1 9.9 6.8 0.1 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4326) DUF4201 PF13870.1 KEG07445.1 - 6.3 6.2 45.0 0.56 9.6 10.0 4.8 4 1 1 5 5 5 0 Domain of unknown function (DUF4201) DUF812 PF05667.6 KEG07445.1 - 6.7 5.0 41.5 0.88 8.0 0.1 4.3 3 1 0 4 4 4 0 Protein of unknown function (DUF812) AAA_13 PF13166.1 KEG07445.1 - 7.5 4.8 37.7 0.013 14.0 12.8 3.4 4 0 0 4 4 4 0 AAA domain TMEM213 PF15192.1 KEG07446.1 - 0.017 15.0 1.9 0.04 13.9 1.3 1.6 1 0 0 1 1 1 0 TMEM213 family DUF1180 PF06679.7 KEG07447.1 - 0.047 13.5 3.2 0.065 13.1 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) GlcNAc PF11397.3 KEG07448.1 - 8.2e-110 367.1 0.0 1.2e-109 366.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) DUF3963 PF13124.1 KEG07448.1 - 0.0033 17.1 2.3 0.0078 15.9 1.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3963) DUF523 PF04463.7 KEG07451.1 - 3.5e-08 33.3 0.0 4.3e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF523) zf-Tim10_DDP PF02953.10 KEG07452.1 - 9.8e-06 24.7 2.4 1.2e-05 24.4 1.7 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger SRP54 PF00448.17 KEG07453.1 - 1.5e-73 246.4 1.1 2.8e-73 245.5 0.7 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 KEG07453.1 - 1.5e-25 89.4 0.2 1.5e-25 89.4 0.2 4.1 3 1 2 5 5 4 1 Signal peptide binding domain SRP54_N PF02881.14 KEG07453.1 - 3.7e-15 55.7 1.2 1e-14 54.3 0.8 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 KEG07453.1 - 1.2e-06 28.0 0.2 3.1e-06 26.7 0.1 1.7 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KEG07453.1 - 1.1e-05 25.3 0.0 2.5e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 KEG07453.1 - 1.8e-05 24.2 0.1 6.3e-05 22.4 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.1 KEG07453.1 - 0.00035 20.7 1.2 0.0042 17.2 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_31 PF13614.1 KEG07453.1 - 0.00036 20.4 0.1 1.1 9.2 0.0 3.1 3 0 0 3 3 3 2 AAA domain MobB PF03205.9 KEG07453.1 - 0.00039 20.1 0.3 0.0018 17.9 0.0 2.2 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 KEG07453.1 - 0.0027 16.5 2.6 0.022 13.5 0.3 3.0 2 1 0 2 2 2 1 ArgK protein AAA_16 PF13191.1 KEG07453.1 - 0.0091 16.0 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.15 KEG07453.1 - 0.013 15.1 0.0 0.04 13.5 0.0 1.8 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_17 PF13207.1 KEG07453.1 - 0.015 16.1 0.0 0.032 15.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KEG07453.1 - 0.016 14.2 0.1 0.04 12.9 0.0 1.7 1 1 0 1 1 1 0 Zeta toxin Methyltransf_24 PF13578.1 KEG07453.1 - 0.016 16.0 0.0 0.043 14.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain ATP_bind_1 PF03029.12 KEG07453.1 - 0.025 14.1 0.3 0.17 11.3 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.22 KEG07453.1 - 0.027 14.7 2.1 3 8.1 0.0 3.0 3 0 0 3 3 3 0 ABC transporter SRPRB PF09439.5 KEG07453.1 - 0.035 13.3 0.5 5.9 6.0 0.1 2.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_25 PF13481.1 KEG07453.1 - 0.05 13.0 0.1 0.19 11.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain SWIB PF02201.13 KEG07453.1 - 0.086 12.5 0.2 0.29 10.8 0.1 2.0 1 0 0 1 1 1 0 SWIB/MDM2 domain ATP-cone PF03477.11 KEG07453.1 - 0.089 13.2 1.3 0.16 12.3 0.2 1.9 2 0 0 2 2 1 0 ATP cone domain Response_reg PF00072.19 KEG07453.1 - 0.093 12.7 0.3 0.28 11.1 0.0 2.0 2 0 0 2 2 1 0 Response regulator receiver domain AAA PF00004.24 KEG07453.1 - 0.11 12.7 1.3 0.58 10.3 0.1 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 KEG07453.1 - 0.76 9.4 6.8 2.1 8.0 2.0 2.7 2 1 0 2 2 2 0 NTPase Pkinase PF00069.20 KEG07455.1 - 1.6e-45 155.3 0.0 1.1e-34 119.7 0.0 3.2 2 1 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 KEG07455.1 - 1.1e-21 77.1 0.0 4.9e-20 71.6 0.0 2.8 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG07455.1 - 7.8e-06 25.0 0.0 1.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KEG07455.1 - 0.075 12.0 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TT_ORF2 PF02957.10 KEG07456.1 - 1.1 10.0 5.1 2.5 8.8 3.5 1.6 1 0 0 1 1 1 0 TT viral ORF2 Prominin PF05478.6 KEG07457.1 - 0.00066 17.3 7.2 0.00066 17.3 5.0 3.4 2 1 1 3 3 3 2 Prominin DUF1451 PF07295.6 KEG07457.1 - 0.18 11.5 23.2 0.65 9.7 1.3 4.6 2 1 3 5 5 5 0 Protein of unknown function (DUF1451) Stathmin PF00836.14 KEG07457.1 - 0.61 9.7 8.3 1.5 8.4 2.6 2.9 2 1 0 2 2 2 0 Stathmin family Baculo_PEP_C PF04513.7 KEG07457.1 - 0.72 9.6 20.8 0.2 11.5 0.4 5.2 1 1 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.3 KEG07457.1 - 2.7 5.2 36.5 0.39 8.0 14.5 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) Fib_alpha PF08702.5 KEG07457.1 - 9.7 6.3 22.4 1.9 8.5 2.1 4.7 1 1 5 6 6 6 0 Fibrinogen alpha/beta chain family WD40 PF00400.27 KEG07458.1 - 8e-52 171.3 10.6 5.2e-11 41.9 0.1 10.3 11 0 0 11 11 11 7 WD domain, G-beta repeat Utp13 PF08625.6 KEG07458.1 - 7e-41 139.1 1.5 1.3e-40 138.3 1.0 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 KEG07458.1 - 0.00022 19.5 5.2 0.1 10.7 0.6 3.7 3 1 0 3 3 3 2 Nucleoporin Nup120/160 UTP15_C PF09384.5 KEG07458.1 - 0.00031 20.4 1.6 0.0006 19.5 1.1 1.4 1 0 0 1 1 1 1 UTP15 C terminal Utp12 PF04003.7 KEG07458.1 - 0.00036 20.4 1.2 0.0007 19.4 0.9 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Nucleoporin_N PF08801.6 KEG07458.1 - 0.00075 18.3 0.1 0.15 10.7 0.0 3.9 2 1 1 3 3 3 1 Nup133 N terminal like Cytochrom_D1 PF02239.11 KEG07458.1 - 0.016 13.5 0.3 1.1 7.4 0.0 3.0 3 1 1 4 4 4 0 Cytochrome D1 heme domain DUF3312 PF11768.3 KEG07458.1 - 0.071 11.3 0.1 1.1 7.3 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3312) tRNA-synt_1e PF01406.14 KEG07459.1 - 2.3e-109 365.1 0.0 3.2e-109 364.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1 PF00133.17 KEG07459.1 - 6.2e-05 21.1 0.0 0.0039 15.2 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KEG07459.1 - 7.4e-05 21.5 0.3 0.0046 15.6 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) Peptidase_C14 PF00656.17 KEG07460.1 - 1.9e-63 214.4 0.1 2.6e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 KEG07460.1 - 0.009 15.8 0.0 0.85 9.4 0.0 2.4 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain DUF3006 PF11213.3 KEG07460.1 - 0.089 12.5 0.0 9.2 6.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3006) Pro_isomerase PF00160.16 KEG07463.1 - 2.1e-39 135.2 0.0 2.5e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD EF-hand_8 PF13833.1 KEG07464.1 - 3.1e-07 29.9 0.1 1.5e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KEG07464.1 - 0.00024 20.7 0.0 0.014 15.1 0.0 3.0 2 1 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 KEG07464.1 - 0.002 18.2 0.1 0.07 13.2 0.0 2.6 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_like PF09279.6 KEG07464.1 - 0.0027 17.7 0.5 0.015 15.3 0.3 2.1 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_1 PF00036.27 KEG07464.1 - 0.076 12.3 0.1 0.92 8.9 0.0 2.4 2 0 0 2 2 2 0 EF hand TPR_12 PF13424.1 KEG07465.1 - 0.0039 17.1 0.6 0.27 11.1 0.1 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEG07465.1 - 0.0041 17.4 0.0 0.73 10.2 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 KEG07465.1 - 0.015 14.9 0.6 0.043 13.4 0.0 2.0 2 0 0 2 2 2 0 TPR repeat TPR_2 PF07719.12 KEG07465.1 - 0.03 14.2 0.7 0.65 10.0 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 KEG07465.1 - 0.081 13.3 0.1 2.5 8.7 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat MAM33 PF02330.11 KEG07466.1 - 1.8e-11 44.2 1.3 2.8e-11 43.5 0.9 1.6 1 1 0 1 1 1 1 Mitochondrial glycoprotein MYCBPAP PF14646.1 KEG07467.1 - 1.9e-08 33.4 0.0 8.7e-05 21.4 0.0 2.9 2 1 0 2 2 2 2 MYCBP-associated protein family Kinesin PF00225.18 KEG07468.1 - 6.2e-87 291.4 0.0 1e-86 290.6 0.0 1.4 1 1 0 1 1 1 1 Kinesin motor domain DUF87 PF01935.12 KEG07468.1 - 0.34 10.6 1.6 4.3 7.0 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF87 Snapin_Pallidin PF14712.1 KEG07469.1 - 2.1 8.6 17.9 4 7.7 1.6 3.5 2 2 0 3 3 3 0 Snapin/Pallidin Vps16_C PF04840.7 KEG07470.1 - 1.3e-26 93.2 0.0 2e-19 69.7 0.0 2.2 2 0 0 2 2 2 2 Vps16, C-terminal region Vps16_N PF04841.8 KEG07470.1 - 4.3e-26 91.3 0.0 4.5e-19 68.2 0.0 2.6 2 1 0 2 2 2 2 Vps16, N-terminal region Carbpep_Y_N PF05388.6 KEG07471.1 - 0.00069 19.7 0.3 1.6 8.9 0.1 2.6 1 1 0 2 2 2 2 Carboxypeptidase Y pro-peptide SQS_PSY PF00494.14 KEG07471.1 - 0.0029 16.9 0.3 0.043 13.1 0.0 2.2 1 1 1 2 2 2 1 Squalene/phytoene synthase FliJ PF02050.11 KEG07471.1 - 0.022 14.7 9.3 0.2 11.6 3.5 2.5 2 0 0 2 2 2 0 Flagellar FliJ protein Syntaxin_2 PF14523.1 KEG07471.1 - 0.076 13.0 5.3 5.8 7.0 1.5 2.5 2 0 0 2 2 2 0 Syntaxin-like protein IncA PF04156.9 KEG07471.1 - 0.21 11.1 5.5 5.4 6.5 3.8 2.2 1 1 0 1 1 1 0 IncA protein AATF-Che1 PF13339.1 KEG07471.1 - 0.28 11.3 10.3 3.6 7.7 2.8 2.8 1 1 2 3 3 3 0 Apoptosis antagonizing transcription factor Baculo_PEP_C PF04513.7 KEG07471.1 - 5.3 6.8 8.7 1.8 8.3 2.1 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2229 PF09989.4 KEG07471.1 - 7.8 5.8 7.4 2.1 7.7 1.1 2.1 1 1 1 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF948 PF06103.6 KEG07471.1 - 7.8 6.4 13.1 4.2 7.3 0.2 3.3 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Mucin PF01456.12 KEG07473.1 - 0.62 9.8 13.5 0.55 10.0 9.0 1.3 1 1 0 1 1 1 0 Mucin-like glycoprotein DUF4509 PF14970.1 KEG07474.1 - 0.25 10.9 2.7 10 5.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4509) PSCyt1 PF07635.6 KEG07474.1 - 2.2 8.6 4.2 23 5.3 0.1 3.3 2 1 1 3 3 3 0 Planctomycete cytochrome C Spore_II_R PF09551.5 KEG07474.1 - 4.1 7.4 8.0 11 6.0 0.7 3.3 3 0 0 3 3 3 0 Stage II sporulation protein R (spore_II_R) GTPase_Cys_C PF12631.2 KEG07474.1 - 10 6.6 8.6 9.5 6.7 0.3 3.5 3 0 0 3 3 3 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE DUF3121 PF11319.3 KEG07475.1 - 3.9 6.9 7.7 0.5 9.8 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3121) Pro_isomerase PF00160.16 KEG07477.1 - 2.7e-14 53.6 0.0 3.6e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Nuc_deoxyrib_tr PF05014.10 KEG07478.1 - 1.1e-27 96.1 0.0 1.3e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase DUF4406 PF14359.1 KEG07478.1 - 0.0017 18.3 0.0 0.003 17.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4406) VSP PF03302.8 KEG07484.1 - 0.036 12.7 3.5 0.066 11.8 2.4 1.5 1 0 0 1 1 1 0 Giardia variant-specific surface protein Peptidase_C58 PF03543.9 KEG07488.1 - 0.079 12.4 0.1 0.095 12.1 0.1 1.1 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen Dscam_C PF12355.3 KEG07490.1 - 0.075 13.2 0.0 0.091 13.0 0.0 1.3 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal Ribosomal_S7 PF00177.16 KEG07491.1 - 7e-38 129.5 0.3 8.2e-38 129.2 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e PDZ_2 PF13180.1 KEG07493.1 - 0.022 14.6 0.0 0.063 13.1 0.0 1.8 2 0 0 2 2 2 0 PDZ domain Ofd1_CTDD PF10637.4 KEG07493.1 - 0.032 13.3 0.4 0.09 11.8 0.3 1.7 1 1 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term FAD_binding_1 PF00667.15 KEG07493.1 - 0.09 12.2 1.6 0.13 11.6 0.4 1.7 2 0 0 2 2 2 0 FAD binding domain zf-CCHC_4 PF14392.1 KEG07493.1 - 0.17 11.5 1.2 0.35 10.5 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCCH PF00642.19 KEG07494.1 - 0.0016 18.0 16.2 0.057 13.1 2.0 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Gastrin PF00918.12 KEG07495.1 - 0.19 12.5 4.1 0.22 12.3 2.8 1.1 1 0 0 1 1 1 0 Gastrin/cholecystokinin family PsbW PF07123.7 KEG07495.1 - 2.9 7.9 5.3 3.5 7.6 3.7 1.1 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) RRM_1 PF00076.17 KEG07499.1 - 1.4e-82 271.2 7.9 6.9e-25 86.4 0.0 4.1 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG07499.1 - 7.6e-56 185.9 3.0 4.4e-16 58.6 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG07499.1 - 1.8e-36 123.7 4.8 3.6e-10 39.5 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KEG07499.1 - 2.7e-08 33.6 0.6 0.16 11.8 0.1 4.3 4 0 0 4 4 4 3 RNA binding motif DUF4523 PF15023.1 KEG07499.1 - 0.0032 16.9 0.0 0.15 11.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4523) OB_RNB PF08206.6 KEG07499.1 - 0.024 14.1 0.1 3 7.4 0.0 3.2 3 0 0 3 3 3 0 Ribonuclease B OB domain TC1 PF15063.1 KEG07499.1 - 0.048 13.1 0.0 0.61 9.6 0.0 2.7 3 0 0 3 3 3 0 Thyroid cancer protein 1 Peptidase_C48 PF02902.14 KEG07500.1 - 4e-05 23.3 0.0 5.6e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Tex_N PF09371.5 KEG07502.1 - 0.061 12.6 0.0 3.1 7.0 0.0 2.5 2 0 0 2 2 2 0 Tex-like protein N-terminal domain zf-Tim10_DDP PF02953.10 KEG07503.1 - 8.2e-11 41.0 3.5 9.3e-11 40.8 2.4 1.0 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 KEG07503.1 - 0.0072 15.7 1.3 0.0076 15.7 0.9 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) TRAP_alpha PF03896.11 KEG07504.1 - 4.3e-20 71.8 0.1 6.5e-20 71.2 0.1 1.3 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit GRP PF07172.6 KEG07504.1 - 0.073 13.5 0.7 0.13 12.7 0.0 1.7 2 0 0 2 2 2 0 Glycine rich protein family DDDD PF10161.4 KEG07504.1 - 0.097 12.3 0.1 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 Putative mitochondrial precursor protein HTH_AsnC-type PF13404.1 KEG07507.1 - 2.3 7.8 6.0 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain UVR PF02151.14 KEG07509.1 - 1.3e-05 24.4 13.4 7.8e-05 22.0 0.2 3.6 3 0 0 3 3 3 2 UvrB/uvrC motif HEAT PF02985.17 KEG07509.1 - 9.7e-05 22.1 2.7 0.11 12.6 0.3 4.0 3 0 0 3 3 3 2 HEAT repeat Exostosin PF03016.10 KEG07511.1 - 3.1e-37 128.2 0.4 4.7e-37 127.6 0.3 1.3 1 0 0 1 1 1 1 Exostosin family Ufm1 PF03671.9 KEG07514.1 - 1e-26 92.4 0.0 1.2e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein DUF3184 PF11380.3 KEG07515.1 - 8.2e-253 840.4 17.9 2.9e-156 521.3 5.7 3.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3184) ubiquitin PF00240.18 KEG07516.1 - 0.0017 17.6 0.0 0.0037 16.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family CysG_dimeriser PF10414.4 KEG07516.1 - 0.047 13.1 0.2 0.15 11.5 0.2 1.9 1 0 0 1 1 1 0 Sirohaem synthase dimerisation region PRP1_N PF06424.7 KEG07516.1 - 0.91 9.8 5.6 0.13 12.5 1.0 1.7 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal TPT PF03151.11 KEG07517.1 - 9.4e-09 35.0 8.1 9.4e-09 35.0 5.6 2.2 1 1 1 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KEG07517.1 - 1.7e-07 30.4 18.0 2.9e-07 29.7 12.5 1.3 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 KEG07517.1 - 3.1e-06 27.2 19.3 0.00026 21.0 1.6 2.4 2 0 0 2 2 2 2 EamA-like transporter family SecA_DEAD PF07517.9 KEG07517.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain Kinesin PF00225.18 KEG07518.1 - 2.2e-34 118.7 0.0 2.3e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain GIT_SHD PF08518.6 KEG07518.1 - 0.056 12.7 1.3 0.075 12.4 0.2 1.7 2 0 0 2 2 2 0 Spa2 homology domain (SHD) of GIT PhoH PF02562.11 KEG07518.1 - 0.16 11.2 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein TPR_11 PF13414.1 KEG07519.1 - 1.7e-17 62.7 6.9 2.9e-09 36.4 1.6 3.1 1 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KEG07519.1 - 3.9e-13 48.4 5.7 9.1e-08 31.4 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEG07519.1 - 3.9e-09 35.7 12.9 5.3e-06 25.9 0.1 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEG07519.1 - 4.3e-06 27.2 10.4 0.00042 20.9 0.7 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KEG07519.1 - 0.00014 21.3 4.1 0.0046 16.6 0.1 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat MIT PF04212.13 KEG07519.1 - 0.0002 21.1 2.7 0.0016 18.3 0.1 2.8 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_12 PF13424.1 KEG07519.1 - 0.0054 16.6 8.3 0.19 11.6 0.2 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEG07519.1 - 0.008 16.4 6.7 0.021 15.1 0.1 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_3 PF07720.7 KEG07519.1 - 0.026 14.2 3.6 0.054 13.3 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KEG07519.1 - 0.038 13.7 0.0 0.038 13.7 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KEG07519.1 - 0.065 13.1 0.2 0.065 13.1 0.2 2.3 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.1 KEG07519.1 - 0.083 13.5 7.2 0.18 12.5 0.1 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEG07519.1 - 0.11 13.0 0.4 0.11 13.0 0.3 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 KEG07519.1 - 0.29 11.0 6.6 0.097 12.5 0.6 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat ARPC4 PF05856.7 KEG07520.1 - 6.1e-70 234.0 0.3 6.8e-70 233.8 0.2 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Aldedh PF00171.17 KEG07522.1 - 0.0041 15.5 2.3 3.4 5.9 0.1 3.0 3 0 0 3 3 3 3 Aldehyde dehydrogenase family Flagellin_N PF00669.15 KEG07522.1 - 0.086 12.6 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region CCT PF06203.9 KEG07523.1 - 0.072 12.7 0.4 0.15 11.6 0.3 1.6 1 0 0 1 1 1 0 CCT motif Phage_glycop_gL PF11108.3 KEG07524.1 - 0.087 12.7 0.6 0.18 11.8 0.4 1.7 1 1 0 1 1 1 0 Viral glycoprotein L DUF2754 PF10953.3 KEG07527.1 - 0.022 14.8 0.7 0.038 14.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) ABC_tran PF00005.22 KEG07529.1 - 2.1e-17 63.6 0.0 4.9e-17 62.5 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KEG07529.1 - 0.00015 21.8 0.0 0.0056 16.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KEG07529.1 - 0.00019 20.9 0.1 0.00042 19.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 KEG07529.1 - 0.00097 18.4 0.0 1.4 8.1 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KEG07529.1 - 0.0017 18.7 0.0 0.0033 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KEG07529.1 - 0.0083 16.2 0.1 0.1 12.7 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 KEG07529.1 - 0.019 15.7 0.0 0.12 13.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KEG07529.1 - 0.049 13.9 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 KEG07529.1 - 0.055 13.2 0.1 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 FliG_C PF01706.11 KEG07529.1 - 0.11 12.4 0.1 0.31 11.0 0.1 1.7 1 0 0 1 1 1 0 FliG C-terminal domain HCV_capsid PF01543.12 KEG07529.1 - 0.16 11.9 0.4 0.4 10.6 0.3 1.6 1 0 0 1 1 1 0 Hepatitis C virus capsid protein G-alpha PF00503.15 KEG07529.1 - 0.4 9.3 0.0 0.69 8.5 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_15 PF13175.1 KEG07529.1 - 0.59 9.1 0.0 1 8.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Vasculin PF15337.1 KEG07530.1 - 0.14 12.6 0.1 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 Vascular protein family Vasculin-like 1 DUF3584 PF12128.3 KEG07531.1 - 0.019 12.3 4.5 0.024 12.0 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HAUS-augmin3 PF14932.1 KEG07531.1 - 0.029 13.5 3.9 0.042 13.0 2.7 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Tektin PF03148.9 KEG07531.1 - 0.047 12.2 8.2 0.065 11.7 5.7 1.1 1 0 0 1 1 1 0 Tektin family DUF106 PF01956.11 KEG07531.1 - 0.065 12.7 0.0 0.16 11.5 0.0 1.5 1 1 0 1 1 1 0 Integral membrane protein DUF106 DNA_Packaging PF11053.3 KEG07531.1 - 0.14 11.8 2.6 0.14 11.8 0.7 1.7 1 1 0 2 2 2 0 Terminase DNA packaging enzyme Atg14 PF10186.4 KEG07531.1 - 0.18 10.7 8.4 0.24 10.3 5.8 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Tho2 PF11262.3 KEG07531.1 - 0.18 10.7 2.0 0.25 10.3 1.4 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Sec8_exocyst PF04048.9 KEG07531.1 - 0.25 10.9 4.2 0.4 10.3 2.9 1.3 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain V_ATPase_I PF01496.14 KEG07531.1 - 0.32 8.7 2.2 0.38 8.5 1.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF904 PF06005.7 KEG07531.1 - 0.85 9.9 12.2 0.064 13.5 5.2 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF904) UPF0449 PF15136.1 KEG07531.1 - 1.1 9.5 4.2 0.69 10.1 0.8 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 OmpH PF03938.9 KEG07531.1 - 1.5 8.7 10.7 2.5 8.0 7.4 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DMPK_coil PF08826.5 KEG07531.1 - 2.4 8.1 12.0 0.95 9.4 3.9 2.3 1 1 0 2 2 2 0 DMPK coiled coil domain like SlyX PF04102.7 KEG07531.1 - 2.9 8.3 8.0 13 6.2 2.7 3.8 2 0 0 2 2 2 0 SlyX WD40 PF00400.27 KEG07532.1 - 4.9e-14 51.5 0.9 1.2e-05 24.9 0.1 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat PQQ_2 PF13360.1 KEG07532.1 - 0.0001 21.8 2.6 0.00014 21.4 0.5 2.1 2 0 0 2 2 2 1 PQQ-like domain Tocopherol_cycl PF14249.1 KEG07532.1 - 0.059 12.0 0.1 0.11 11.2 0.1 1.3 1 0 0 1 1 1 0 Tocopherol cyclase PQQ_3 PF13570.1 KEG07532.1 - 0.37 11.1 4.5 7.2 7.0 0.1 4.2 4 0 0 4 4 4 0 PQQ-like domain GAS2 PF02187.12 KEG07534.1 - 0.066 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Growth-Arrest-Specific Protein 2 Domain Galactosyl_T PF01762.16 KEG07536.1 - 3.5e-09 36.5 0.0 0.0004 20.0 0.0 3.6 3 1 0 3 3 3 2 Galactosyltransferase DUF3357 PF11837.3 KEG07536.1 - 0.085 12.7 0.2 0.63 9.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) Aa_trans PF01490.13 KEG07537.1 - 1.2e-52 178.8 32.4 1.5e-52 178.5 22.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KEG07537.1 - 8.7e-05 21.5 28.6 0.0003 19.7 19.3 2.3 1 1 1 2 2 2 1 Tryptophan/tyrosine permease family DUF4231 PF14015.1 KEG07537.1 - 2.5 8.1 9.9 0.2 11.6 1.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Pribosyltran_N PF13793.1 KEG07539.1 - 1.4e-41 140.8 0.4 1.7e-25 88.9 0.0 2.8 2 1 1 3 3 3 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KEG07539.1 - 3.4e-23 82.3 0.9 1.4e-22 80.3 0.2 2.2 2 1 1 3 3 3 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KEG07539.1 - 1e-11 44.6 0.2 2.4e-11 43.4 0.2 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KEG07539.1 - 0.04 13.1 0.1 0.07 12.3 0.1 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase RNase_Zc3h12a PF11977.3 KEG07541.1 - 0.00058 19.7 0.7 0.013 15.3 0.1 3.1 3 1 0 3 3 3 1 Zc3h12a-like Ribonuclease NYN domain Xpo1 PF08389.7 KEG07542.1 - 2.4e-20 72.9 0.0 2.7e-19 69.5 0.0 2.7 2 0 0 2 2 2 1 Exportin 1-like protein HEAT PF02985.17 KEG07542.1 - 0.005 16.8 0.3 2.8 8.2 0.0 3.9 3 0 0 3 3 3 2 HEAT repeat PI3_PI4_kinase PF00454.22 KEG07543.1 - 1e-46 159.3 0.0 1.3e-34 119.7 0.0 2.2 2 0 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 KEG07543.1 - 1.2e-08 34.2 0.1 2.7e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 FATC domain Fucokinase PF07959.7 KEG07545.1 - 1.6e-46 158.7 0.0 4.9e-46 157.1 0.0 1.7 1 1 0 1 1 1 1 L-fucokinase GHMP_kinases_C PF08544.8 KEG07545.1 - 4.4e-07 30.0 0.0 1.3e-06 28.4 0.0 1.9 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 KEG07545.1 - 4.6e-06 26.6 0.4 4.6e-06 26.6 0.3 2.4 3 0 0 3 3 3 1 GHMP kinases N terminal domain MMR_HSR1 PF01926.18 KEG07547.1 - 1.6e-11 44.1 0.0 3.1e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KEG07547.1 - 3.4e-06 26.9 0.2 8.7e-05 22.3 0.1 2.3 1 1 1 2 2 2 1 Dynamin family DUF258 PF03193.11 KEG07547.1 - 3.7e-05 22.9 0.0 7.6e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KEG07547.1 - 0.00097 18.6 0.0 0.0022 17.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain FeoB_N PF02421.13 KEG07547.1 - 0.0071 15.6 0.0 0.019 14.2 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B ABC_tran PF00005.22 KEG07547.1 - 0.012 15.8 0.1 0.24 11.6 0.0 2.2 2 0 0 2 2 2 0 ABC transporter GTP_EFTU PF00009.22 KEG07547.1 - 0.015 14.7 0.0 7.9 5.8 0.0 3.1 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Miro PF08477.8 KEG07547.1 - 0.021 15.3 0.0 0.078 13.4 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein Stimulus_sens_1 PF13756.1 KEG07547.1 - 0.036 14.4 0.2 0.086 13.2 0.1 1.6 1 0 0 1 1 1 0 Stimulus-sensing domain Gtr1_RagA PF04670.7 KEG07547.1 - 0.079 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MobB PF03205.9 KEG07547.1 - 0.085 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Parvo_NS1 PF01057.12 KEG07547.1 - 0.097 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 IIGP PF05049.8 KEG07547.1 - 0.12 11.1 0.0 0.54 9.0 0.0 1.8 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Alginate_lyase2 PF08787.6 KEG07547.1 - 0.14 11.7 0.2 0.34 10.5 0.1 1.6 1 0 0 1 1 1 0 Alginate lyase DUF1738 PF08401.6 KEG07548.1 - 0.00097 18.8 0.0 0.0059 16.3 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1738) DUF1738 PF08401.6 KEG07549.1 - 0.0035 17.0 0.5 0.22 11.2 0.1 3.0 2 1 1 3 3 3 1 Domain of unknown function (DUF1738) AAA PF00004.24 KEG07550.1 - 5.6e-52 175.4 0.0 3.8e-40 137.1 0.0 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEG07550.1 - 1.9e-08 34.4 0.6 0.039 13.9 0.0 4.2 2 2 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 KEG07550.1 - 1.4e-06 28.4 0.1 0.12 12.4 0.0 3.5 3 1 0 3 3 3 2 AAA domain AAA_5 PF07728.9 KEG07550.1 - 9.1e-06 25.4 0.0 0.026 14.2 0.0 3.4 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KEG07550.1 - 0.00021 20.4 0.0 0.00071 18.6 0.0 1.9 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 KEG07550.1 - 0.0005 19.5 0.0 0.16 11.3 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein NACHT PF05729.7 KEG07550.1 - 0.00062 19.4 0.0 1.2 8.7 0.0 2.8 2 0 0 2 2 2 2 NACHT domain TIP49 PF06068.8 KEG07550.1 - 0.0012 17.6 0.0 0.0029 16.4 0.0 1.6 2 0 0 2 2 2 1 TIP49 C-terminus RNA_helicase PF00910.17 KEG07550.1 - 0.0012 18.9 0.0 0.32 11.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.1 KEG07550.1 - 0.0014 18.0 0.1 0.77 9.1 0.0 3.1 3 1 0 3 3 3 1 AAA domain Mg_chelatase PF01078.16 KEG07550.1 - 0.0018 17.4 0.0 0.063 12.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Vps4_C PF09336.5 KEG07550.1 - 0.0025 17.6 0.0 0.0098 15.7 0.0 2.0 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_33 PF13671.1 KEG07550.1 - 0.003 17.4 0.0 1.2 8.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 KEG07550.1 - 0.0042 16.0 0.0 3 6.6 0.0 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF815) Molydop_binding PF01568.16 KEG07550.1 - 0.0046 16.7 0.0 0.013 15.3 0.0 1.7 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Sigma54_activ_2 PF14532.1 KEG07550.1 - 0.0048 16.9 0.0 0.47 10.5 0.0 3.0 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_2 PF07724.9 KEG07550.1 - 0.0054 16.6 0.0 0.09 12.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 KEG07550.1 - 0.0077 17.0 0.0 0.68 10.7 0.0 2.9 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.22 KEG07550.1 - 0.0093 16.2 0.0 1.4 9.2 0.0 2.9 3 0 0 3 3 2 1 ABC transporter Zeta_toxin PF06414.7 KEG07550.1 - 0.0094 15.0 0.0 0.14 11.2 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin Sigma54_activat PF00158.21 KEG07550.1 - 0.014 14.8 0.0 7.4 6.0 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.1 KEG07550.1 - 0.017 15.0 0.0 0.8 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain CDC48_N PF02359.13 KEG07550.1 - 0.017 15.0 0.0 0.06 13.3 0.0 1.9 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain FtsK_SpoIIIE PF01580.13 KEG07550.1 - 0.033 13.6 0.0 0.078 12.4 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_19 PF13245.1 KEG07550.1 - 0.042 13.6 0.1 17 5.2 0.0 3.2 3 0 0 3 3 2 0 Part of AAA domain Arch_ATPase PF01637.13 KEG07550.1 - 0.045 13.4 0.0 5.5 6.6 0.0 3.2 3 0 0 3 3 3 0 Archaeal ATPase MCM PF00493.18 KEG07550.1 - 0.05 12.3 0.0 1.4 7.6 0.0 2.6 3 0 0 3 3 3 0 MCM2/3/5 family AAA_24 PF13479.1 KEG07550.1 - 0.05 13.1 0.0 2.6 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 KEG07550.1 - 0.17 10.5 0.0 0.29 9.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein IBR PF01485.16 KEG07551.1 - 6.9e-15 54.6 25.2 3.1e-09 36.5 6.6 4.5 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 KEG07551.1 - 7.6e-05 22.4 11.1 7.6e-05 22.4 7.7 4.6 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.1 KEG07551.1 - 0.0013 18.7 12.7 0.0013 18.7 8.8 4.9 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.27 KEG07553.1 - 0.0069 16.2 5.0 3.1 7.8 0.4 4.4 5 0 0 5 5 5 2 WD domain, G-beta repeat PQQ_3 PF13570.1 KEG07553.1 - 0.012 15.9 3.7 0.31 11.3 0.1 2.8 2 0 0 2 2 2 0 PQQ-like domain LCE PF14672.1 KEG07553.1 - 0.75 10.3 3.8 0.87 10.1 0.1 2.3 2 0 0 2 2 2 0 Late cornified envelope V-ATPase_G PF03179.10 KEG07556.1 - 7.7e-19 67.9 14.5 8.3e-19 67.8 10.1 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit GPCR_chapero_1 PF11904.3 KEG07556.1 - 0.07 12.2 3.0 0.08 12.0 2.1 1.0 1 0 0 1 1 1 0 GPCR-chaperone K167R PF08065.7 KEG07556.1 - 0.078 13.0 3.5 0.22 11.6 2.4 1.7 1 1 0 1 1 1 0 K167R (NUC007) repeat Sep15_SelM PF08806.6 KEG07556.1 - 0.091 12.5 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Sep15/SelM redox domain ARD PF03079.9 KEG07556.1 - 0.17 11.8 2.7 0.18 11.7 1.8 1.1 1 0 0 1 1 1 0 ARD/ARD' family DUF3154 PF11351.3 KEG07556.1 - 0.39 10.4 6.6 0.19 11.5 2.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3154) DUF2072 PF09845.4 KEG07556.1 - 0.64 9.9 3.6 0.78 9.6 2.5 1.2 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) DUF3552 PF12072.3 KEG07556.1 - 0.68 9.1 18.7 1.6 7.9 12.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) COX16 PF14138.1 KEG07556.1 - 1.1 9.5 6.1 1.1 9.4 3.7 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 vATP-synt_E PF01991.13 KEG07556.1 - 4.3 6.5 14.7 5.5 6.2 10.2 1.3 1 1 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Toprim_C_rpt PF13368.1 KEG07556.1 - 4.3 7.8 5.8 26 5.3 1.1 2.3 2 1 0 2 2 2 0 Topoisomerase C-terminal repeat Glyco_transf_8 PF01501.15 KEG07558.1 - 1.4e-16 60.6 0.0 2.2e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 KEG07558.1 - 0.018 14.4 0.1 0.032 13.5 0.1 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative Exo_endo_phos PF03372.18 KEG07561.1 - 0.02 14.8 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family TPD52 PF04201.10 KEG07562.1 - 0.0058 16.3 5.0 0.064 12.9 1.1 2.5 2 0 0 2 2 2 2 Tumour protein D52 family SNF2_N PF00176.18 KEG07563.1 - 3.5e-71 239.4 0.0 5.7e-71 238.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEG07563.1 - 1.1e-15 57.2 0.1 2.9e-15 55.8 0.0 1.8 2 0 0 2 2 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEG07563.1 - 9.6e-07 28.8 0.4 3.2e-05 23.8 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KEG07563.1 - 1.2e-05 24.8 0.0 2.3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase CENP-T PF15511.1 KEG07563.1 - 0.012 14.9 13.6 0.021 14.1 9.4 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T AAA_22 PF13401.1 KEG07563.1 - 0.014 15.5 0.0 0.063 13.4 0.0 2.2 1 1 0 1 1 1 0 AAA domain CDC45 PF02724.9 KEG07563.1 - 0.11 10.4 13.4 0.17 9.8 9.3 1.2 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.6 KEG07563.1 - 0.26 9.3 3.7 0.42 8.6 2.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 IncA PF04156.9 KEG07563.1 - 0.62 9.6 8.1 1.6 8.2 5.6 1.7 1 0 0 1 1 1 0 IncA protein SPX PF03105.14 KEG07563.1 - 0.97 9.1 9.6 0.32 10.7 3.8 2.0 2 0 0 2 2 2 0 SPX domain PPP4R2 PF09184.6 KEG07563.1 - 2.8 7.4 16.7 5.2 6.5 11.6 1.4 1 0 0 1 1 1 0 PPP4R2 Aldedh PF00171.17 KEG07564.1 - 4.3e-129 430.8 1.0 4.9e-129 430.6 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family VPS28 PF03997.7 KEG07565.1 - 1.7e-41 141.9 0.0 2e-41 141.6 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein DUF445 PF04286.7 KEG07565.1 - 0.13 11.7 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Lipase_GDSL PF00657.17 KEG07566.1 - 0.41 10.4 2.8 1.1 8.9 0.1 2.9 2 1 0 3 3 3 0 GDSL-like Lipase/Acylhydrolase CENP-F_leu_zip PF10473.4 KEG07568.1 - 0.0045 16.8 5.0 0.0045 16.8 3.5 3.3 3 0 0 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 KEG07568.1 - 0.0066 16.0 4.0 0.0066 16.0 2.8 3.3 2 1 1 3 3 3 1 IncA protein DUF3584 PF12128.3 KEG07568.1 - 0.079 10.2 24.6 0.11 9.7 17.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_13 PF13166.1 KEG07568.1 - 0.39 9.1 6.7 0.55 8.6 4.1 1.6 1 1 0 1 1 1 0 AAA domain Spc7 PF08317.6 KEG07568.1 - 0.75 8.3 16.6 0.1 11.2 4.0 2.9 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF2852 PF11014.3 KEG07568.1 - 2.4 8.1 6.2 0.82 9.6 2.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) CASP_C PF08172.7 KEG07568.1 - 9.9 5.1 18.9 0.09 11.7 0.8 3.8 2 1 0 2 2 2 0 CASP C terminal SRP19 PF01922.12 KEG07569.1 - 0.08 13.5 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 SRP19 protein IQ PF00612.22 KEG07572.1 - 1.3e-13 49.2 63.4 0.00016 21.0 0.9 9.9 10 0 0 10 10 10 7 IQ calmodulin-binding motif Med27 PF11571.3 KEG07572.1 - 0.0085 16.1 0.1 0.023 14.7 0.1 1.7 1 0 0 1 1 1 1 Mediator complex subunit 27 Telomere_reg-2 PF10193.4 KEG07574.1 - 0.00052 20.2 0.1 0.0016 18.7 0.0 1.9 2 0 0 2 2 2 1 Telomere length regulation protein DUF1275 PF06912.6 KEG07577.1 - 0.047 12.8 0.1 0.07 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) PAP_assoc PF03828.14 KEG07578.1 - 1.1e-16 60.5 0.0 2.6e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase Ribosomal_L16 PF00252.13 KEG07579.1 - 3e-22 78.8 0.0 3.7e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DUF108 PF01958.13 KEG07581.1 - 0.062 13.5 0.2 0.085 13.0 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function DUF108 SRPRB PF09439.5 KEG07584.1 - 1.2e-24 86.5 0.0 6.8e-24 84.0 0.0 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 KEG07584.1 - 3.1e-09 36.3 0.0 2.8e-08 33.1 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KEG07584.1 - 3e-08 33.3 0.0 3.5e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KEG07584.1 - 5.6e-06 26.3 0.0 9.3e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 KEG07584.1 - 7.1e-05 21.6 0.0 0.12 10.9 0.2 2.1 1 1 0 2 2 2 2 G-protein alpha subunit Miro PF08477.8 KEG07584.1 - 0.00054 20.4 0.0 0.00099 19.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 KEG07584.1 - 0.0028 16.8 0.0 0.0047 16.0 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_33 PF13671.1 KEG07584.1 - 0.0098 15.7 0.1 0.019 14.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.17 KEG07584.1 - 0.011 15.2 0.5 0.24 10.8 0.2 2.2 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain AAA_16 PF13191.1 KEG07584.1 - 0.026 14.5 3.2 0.25 11.2 2.2 2.1 1 1 0 1 1 1 0 AAA ATPase domain cobW PF02492.14 KEG07584.1 - 0.03 13.7 0.4 0.099 12.0 0.1 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 KEG07584.1 - 0.043 13.9 0.0 0.094 12.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain NAD_binding_3 PF03447.11 KEG07584.1 - 0.055 13.8 0.7 0.37 11.2 0.1 2.1 1 1 1 2 2 2 0 Homoserine dehydrogenase, NAD binding domain NACHT PF05729.7 KEG07584.1 - 0.066 12.8 0.2 0.78 9.3 0.1 2.1 2 0 0 2 2 2 0 NACHT domain DUF2855 PF11017.3 KEG07584.1 - 0.074 12.1 0.0 0.084 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) AAA_29 PF13555.1 KEG07584.1 - 0.084 12.4 0.1 0.19 11.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mg_chelatase PF01078.16 KEG07584.1 - 0.092 11.8 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF463 PF04317.7 KEG07584.1 - 0.099 11.1 0.0 3.6 6.0 0.0 2.1 2 0 0 2 2 2 0 YcjX-like family, DUF463 PduV-EutP PF10662.4 KEG07584.1 - 0.1 12.0 0.1 0.8 9.1 0.0 2.2 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.17 KEG07584.1 - 0.15 10.8 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Septin PF00735.13 KEG07584.1 - 0.17 10.8 0.0 0.31 9.9 0.0 1.4 1 0 0 1 1 1 0 Septin Arch_ATPase PF01637.13 KEG07584.1 - 0.18 11.5 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase WD40 PF00400.27 KEG07585.1 - 1.5e-12 46.8 6.7 0.042 13.7 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF3312 PF11768.3 KEG07585.1 - 0.016 13.4 0.0 0.062 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) Ribosomal_S5 PF00333.15 KEG07585.1 - 0.067 12.9 0.8 4.5 7.0 0.2 3.3 3 0 0 3 3 3 0 Ribosomal protein S5, N-terminal domain LIM PF00412.17 KEG07586.1 - 3.6e-05 23.7 1.1 6.2e-05 22.9 0.8 1.4 1 0 0 1 1 1 1 LIM domain DUF2039 PF10217.4 KEG07586.1 - 0.04 13.9 0.3 0.073 13.0 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) DZR PF12773.2 KEG07586.1 - 0.59 10.0 4.0 2.7 7.9 2.8 2.0 1 1 0 1 1 1 0 Double zinc ribbon tRNA_lig_CPD PF08302.6 KEG07587.1 - 1.6e-08 34.0 0.2 1.3e-06 27.8 0.0 2.1 1 1 1 2 2 2 2 Fungal tRNA ligase phosphodiesterase domain WD40 PF00400.27 KEG07590.1 - 0.0084 15.9 1.3 4.7 7.2 0.0 5.0 6 0 0 6 6 6 1 WD domain, G-beta repeat AAA_13 PF13166.1 KEG07591.1 - 0.0021 16.6 10.6 0.0021 16.6 7.3 1.6 2 0 0 2 2 2 1 AAA domain Ctf8 PF09696.5 KEG07591.1 - 0.024 14.4 0.4 0.081 12.7 0.0 2.1 2 0 0 2 2 2 0 Ctf8 PerC PF06069.6 KEG07591.1 - 4 7.5 9.2 0.17 11.9 0.3 2.9 3 0 0 3 3 3 0 PerC transcriptional activator Lipase_GDSL_2 PF13472.1 KEG07593.1 - 0.00071 19.7 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family YycC PF14174.1 KEG07593.1 - 0.21 11.2 1.2 0.36 10.5 0.1 1.9 2 0 0 2 2 2 0 YycC-like protein RHS_repeat PF05593.9 KEG07594.1 - 0.15 12.2 0.3 14 6.0 0.0 2.3 2 0 0 2 2 2 0 RHS Repeat AdoHcyase PF05221.12 KEG07596.1 - 6.8e-141 467.8 0.0 7.8e-141 467.6 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 KEG07596.1 - 1.1e-87 291.9 1.3 1.6e-87 291.4 0.9 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 KEG07596.1 - 4.4e-10 38.9 0.0 8.3e-10 38.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 KEG07596.1 - 0.00011 22.1 0.2 0.0005 20.0 0.1 2.1 1 1 0 1 1 1 1 TrkA-N domain IlvN PF07991.7 KEG07596.1 - 0.00012 21.5 0.1 0.00017 20.9 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_7 PF13241.1 KEG07596.1 - 0.0066 16.6 0.1 0.016 15.4 0.1 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.14 KEG07596.1 - 0.019 14.0 0.4 0.09 11.8 0.3 1.9 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Oxidored_nitro PF00148.14 KEG07596.1 - 0.02 13.5 0.1 0.59 8.7 0.1 2.1 1 1 1 2 2 2 0 Nitrogenase component 1 type Oxidoreductase SSF PF00474.12 KEG07597.1 - 0.17 10.5 5.2 0.18 10.4 3.6 1.1 1 0 0 1 1 1 0 Sodium:solute symporter family DUF2881 PF11087.3 KEG07597.1 - 2 7.9 13.7 0.88 9.0 1.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2881) Med3 PF11593.3 KEG07599.1 - 4.2 6.5 12.8 2.5 7.2 5.1 2.0 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Tyr-DNA_phospho PF06087.7 KEG07601.1 - 2.6e-92 309.7 0.0 2.9e-92 309.6 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 KEG07601.1 - 0.013 15.2 0.0 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 PLD-like domain Ras PF00071.17 KEG07602.1 - 3.7e-48 162.9 0.0 4.8e-48 162.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEG07602.1 - 5e-21 75.3 0.1 7.9e-21 74.7 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEG07602.1 - 7.1e-15 54.6 0.2 1.1e-14 54.0 0.1 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KEG07602.1 - 0.00011 21.7 0.1 0.00062 19.2 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KEG07602.1 - 0.00019 20.6 0.0 0.00023 20.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KEG07602.1 - 0.00053 19.9 0.1 0.0011 18.9 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.5 KEG07602.1 - 0.0049 16.1 0.0 0.0074 15.5 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 KEG07602.1 - 0.03 14.0 0.0 0.066 12.8 0.0 1.5 2 0 0 2 2 2 0 Archaeal ATPase AAA_14 PF13173.1 KEG07602.1 - 0.09 12.6 0.0 0.24 11.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain FAD-oxidase_C PF02913.14 KEG07603.1 - 0.044 13.1 0.0 0.057 12.7 0.0 1.1 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain Hydrolase_3 PF08282.7 KEG07604.1 - 3.3e-45 154.6 0.0 8.8e-45 153.2 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 KEG07604.1 - 3.6e-12 46.1 0.2 8.1e-08 31.8 0.0 2.3 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.2 KEG07604.1 - 3.3e-05 24.1 0.1 0.00063 19.9 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KEG07604.1 - 3.7e-05 24.2 0.5 0.00029 21.3 0.3 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.11 KEG07604.1 - 0.0029 16.5 0.2 0.075 11.9 0.0 2.7 3 0 0 3 3 3 1 Trehalose-phosphatase zf-DHHC PF01529.15 KEG07605.1 - 5.3e-27 94.3 0.2 1.4e-26 92.9 0.1 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF2207 PF09972.4 KEG07605.1 - 0.23 10.0 0.0 1.8 7.0 0.0 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF1049 PF06305.6 KEG07605.1 - 0.97 8.9 6.0 0.19 11.2 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF4083 PF13314.1 KEG07605.1 - 2.4 8.0 4.3 23 4.9 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) ABC2_membrane_3 PF12698.2 KEG07605.1 - 3.5 6.5 8.8 4.1 6.3 2.9 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein Histone PF00125.19 KEG07606.1 - 2.1e-15 56.5 0.5 2.9e-15 56.1 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KEG07606.1 - 0.0068 16.4 0.2 0.011 15.7 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Aminotran_5 PF00266.14 KEG07607.1 - 3.9e-07 29.1 0.0 6e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DUF3042 PF11240.3 KEG07608.1 - 0.44 10.3 1.7 1.2 8.9 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) DUF4633 PF15464.1 KEG07608.1 - 1.2 8.9 7.6 0.22 11.3 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4633) BAF1_ABF1 PF04684.8 KEG07609.1 - 0.025 13.4 1.7 0.029 13.2 1.2 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor HNH_3 PF13392.1 KEG07610.1 - 0.18 11.2 0.6 0.38 10.1 0.5 1.5 1 0 0 1 1 1 0 HNH endonuclease M20_dimer PF07687.9 KEG07611.1 - 1.6e-17 63.2 0.0 2.9e-17 62.4 0.0 1.4 1 1 0 1 1 1 1 Peptidase dimerisation domain DUF1214 PF06742.6 KEG07611.1 - 0.14 12.6 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1214) EF1G PF00647.14 KEG07614.1 - 9.6e-47 157.1 0.1 2.7e-46 155.6 0.1 1.7 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 KEG07614.1 - 1e-15 57.4 0.4 2.2e-15 56.3 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KEG07614.1 - 4.5e-09 36.3 0.0 1.2e-08 35.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KEG07614.1 - 4.2e-06 26.8 0.0 1e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KEG07614.1 - 3.3e-05 24.2 0.6 0.0016 18.8 0.3 2.7 2 1 1 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KEG07614.1 - 0.0025 17.7 0.0 0.0089 16.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KEG07614.1 - 0.0025 17.6 3.2 0.0035 17.1 0.0 2.5 2 1 1 3 3 3 1 Glutathione S-transferase, C-terminal domain Ribosomal_60s PF00428.14 KEG07614.1 - 0.49 10.8 8.1 1 9.8 5.6 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Asparaginase PF00710.15 KEG07618.1 - 3.1e-70 236.5 0.0 4.2e-66 222.9 0.0 2.0 2 0 0 2 2 2 2 Asparaginase Ribosomal_60s PF00428.14 KEG07619.1 - 3.3e-18 65.8 10.1 4.1e-18 65.5 7.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein EndIII_4Fe-2S PF10576.4 KEG07619.1 - 0.041 14.0 2.1 0.1 12.8 1.4 1.7 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III GRP PF07172.6 KEG07619.1 - 4.6 7.7 8.4 0.36 11.3 2.2 1.8 1 1 1 2 2 2 0 Glycine rich protein family TBCC PF07986.7 KEG07620.1 - 1e-33 115.2 13.7 4.7e-14 51.8 0.4 3.7 3 0 0 3 3 3 3 Tubulin binding cofactor C Pkinase PF00069.20 KEG07620.1 - 0.0013 17.9 0.0 0.01 15.0 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain CAP_C PF08603.6 KEG07620.1 - 0.024 13.9 2.8 0.12 11.7 0.1 2.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) C terminal Kdo PF06293.9 KEG07620.1 - 0.2 10.7 0.0 0.43 9.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Metallophos PF00149.23 KEG07621.1 - 3.7e-20 72.1 0.0 2.6e-19 69.3 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase CDC45 PF02724.9 KEG07621.1 - 2.5 6.0 5.9 3.5 5.5 4.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Peptidase_C48 PF02902.14 KEG07623.1 - 4.7e-16 59.0 0.0 3.6e-15 56.1 0.0 2.2 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain TilS PF09179.6 KEG07623.1 - 3.6 7.6 5.8 2.6 8.1 0.1 3.1 3 0 0 3 3 3 0 TilS substrate binding domain NifW PF03206.9 KEG07625.1 - 0.13 12.3 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 Nitrogen fixation protein NifW Laminin_EGF PF00053.19 KEG07626.1 - 0.00038 20.3 16.3 0.00038 20.3 11.3 5.7 2 1 2 4 4 4 1 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 KEG07626.1 - 0.01 15.9 78.0 0.03 14.4 7.2 5.6 5 0 0 5 5 5 0 EGF-like domain hEGF PF12661.2 KEG07626.1 - 7.6 6.8 38.3 0.094 12.8 1.2 6.6 5 1 0 5 5 5 0 Human growth factor-like EGF PPR_2 PF13041.1 KEG07628.1 - 3.7e-12 46.0 4.5 1.9e-06 27.7 0.1 4.0 1 1 3 4 4 4 4 PPR repeat family PPR_3 PF13812.1 KEG07628.1 - 8.6e-10 38.1 1.0 0.00087 19.3 0.0 5.1 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR PF01535.15 KEG07628.1 - 8.9e-08 31.6 5.6 0.006 16.4 0.0 4.9 4 1 0 4 4 4 3 PPR repeat Cas_Csd1 PF09709.5 KEG07628.1 - 0.024 12.9 0.5 0.034 12.4 0.1 1.4 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csd1) Taxilin PF09728.4 KEG07629.1 - 6.1e-05 22.2 40.3 6.1e-05 22.2 27.9 2.2 1 1 1 2 2 2 1 Myosin-like coiled-coil protein DUF972 PF06156.8 KEG07629.1 - 0.018 15.4 6.3 0.018 15.4 4.3 4.6 1 1 4 5 5 5 0 Protein of unknown function (DUF972) DinI PF06183.8 KEG07629.1 - 0.026 14.5 5.7 0.04 13.9 2.4 2.6 1 1 1 2 2 2 0 DinI-like family Curto_V3 PF07436.6 KEG07629.1 - 0.045 13.8 1.6 7.4 6.7 0.2 2.6 2 0 0 2 2 2 0 Curtovirus V3 protein Reo_sigmaC PF04582.7 KEG07629.1 - 2.8 7.0 8.0 8.7 5.4 0.3 2.4 1 1 2 3 3 3 0 Reovirus sigma C capsid protein ZYG-11_interact PF05884.7 KEG07629.1 - 4.1 6.4 11.7 0.46 9.5 2.1 2.3 2 0 0 2 2 2 0 Interactor of ZYG-11 DUF948 PF06103.6 KEG07629.1 - 5.2 7.0 16.9 3.2 7.6 1.4 3.5 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) AMNp_N PF10423.4 KEG07631.1 - 0.0063 16.1 0.0 0.0092 15.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial AMP nucleoside phosphorylase N-terminus Cast PF10174.4 KEG07632.1 - 0.00034 18.8 7.7 0.00039 18.6 5.3 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone CALCOCO1 PF07888.6 KEG07632.1 - 0.0005 18.4 1.5 0.00056 18.3 1.0 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like DUF3287 PF11690.3 KEG07632.1 - 0.0041 17.1 1.2 0.0052 16.8 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3287) Prefoldin_2 PF01920.15 KEG07632.1 - 0.011 15.4 1.6 0.022 14.4 1.1 1.6 1 0 0 1 1 1 0 Prefoldin subunit Laminin_I PF06008.9 KEG07632.1 - 0.031 13.6 6.0 0.039 13.2 4.2 1.1 1 0 0 1 1 1 0 Laminin Domain I Atg14 PF10186.4 KEG07632.1 - 0.036 13.0 5.4 0.041 12.8 3.8 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Tho2 PF11262.3 KEG07632.1 - 0.036 13.1 3.8 0.046 12.7 2.7 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 RNF111_N PF15303.1 KEG07632.1 - 0.038 13.4 1.5 0.044 13.3 1.1 1.0 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus BamHI PF02923.10 KEG07632.1 - 0.057 13.3 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease BamHI Spc7 PF08317.6 KEG07632.1 - 0.072 11.7 3.6 0.081 11.5 2.5 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.14 KEG07632.1 - 0.081 10.7 1.1 0.084 10.7 0.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Phage_GPO PF05929.6 KEG07632.1 - 0.083 12.1 2.5 0.092 11.9 1.7 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF972 PF06156.8 KEG07632.1 - 0.09 13.1 0.9 0.13 12.6 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Sds3 PF08598.6 KEG07632.1 - 0.096 12.1 2.8 0.14 11.6 1.9 1.4 1 1 0 1 1 1 0 Sds3-like DUF3847 PF12958.2 KEG07632.1 - 0.17 11.6 3.6 0.31 10.8 2.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3847) Prefoldin PF02996.12 KEG07632.1 - 0.17 11.5 3.3 0.26 10.9 2.3 1.4 1 0 0 1 1 1 0 Prefoldin subunit Ax_dynein_light PF10211.4 KEG07632.1 - 0.19 11.5 5.4 0.23 11.2 3.8 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain OmpH PF03938.9 KEG07632.1 - 0.21 11.5 6.5 0.26 11.2 4.5 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF948 PF06103.6 KEG07632.1 - 0.25 11.2 1.4 0.35 10.7 1.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF904 PF06005.7 KEG07632.1 - 0.31 11.3 4.0 0.53 10.6 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) YlqD PF11068.3 KEG07632.1 - 0.4 10.7 8.3 0.52 10.3 5.8 1.2 1 0 0 1 1 1 0 YlqD protein DUF342 PF03961.8 KEG07632.1 - 0.43 8.9 2.1 0.47 8.8 1.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF812 PF05667.6 KEG07632.1 - 0.48 8.8 6.9 0.56 8.6 4.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) APG6 PF04111.7 KEG07632.1 - 1.5 7.7 7.3 1.9 7.4 5.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Mnd1 PF03962.10 KEG07632.1 - 2.2 7.9 7.2 2.7 7.5 5.0 1.2 1 0 0 1 1 1 0 Mnd1 family FlxA PF14282.1 KEG07632.1 - 5.6 6.9 15.5 14 5.6 10.6 1.7 1 1 1 2 2 2 0 FlxA-like protein RVT_1 PF00078.22 KEG07635.1 - 0.0045 16.3 0.0 0.0069 15.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NAC PF01849.13 KEG07637.1 - 1e-19 69.8 0.1 1.3e-19 69.4 0.1 1.2 1 0 0 1 1 1 1 NAC domain MORN PF02493.15 KEG07638.1 - 4.9e-20 69.9 70.1 0.00032 20.2 0.5 9.4 10 0 0 10 10 10 8 MORN repeat CH PF00307.26 KEG07639.1 - 0.0044 17.0 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain ATG16 PF08614.6 KEG07639.1 - 0.0078 16.0 4.5 0.0078 16.0 3.2 4.6 2 2 2 4 4 4 1 Autophagy protein 16 (ATG16) CAMSAP_CH PF11971.3 KEG07639.1 - 0.055 13.1 0.0 0.21 11.2 0.0 2.0 2 0 0 2 2 2 0 CAMSAP CH domain GCV_T PF01571.16 KEG07640.1 - 1.9e-56 190.7 0.0 2.4e-56 190.4 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KEG07640.1 - 1.4e-20 73.0 0.2 2.5e-20 72.3 0.2 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Aminotran_1_2 PF00155.16 KEG07641.1 - 9.9e-76 255.0 0.0 1.1e-75 254.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 KEG07641.1 - 0.00037 19.1 0.0 0.00048 18.8 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.12 KEG07641.1 - 0.0027 16.8 0.0 0.044 12.8 0.0 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 KEG07641.1 - 0.0034 16.5 0.0 0.0065 15.6 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KEG07641.1 - 0.011 14.5 0.0 0.019 13.6 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 KEG07641.1 - 0.038 12.2 0.0 0.058 11.6 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KEG07642.1 - 6.5e-65 219.4 0.0 7.3e-65 219.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KEG07642.1 - 1e-05 24.7 0.0 1.8e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 KEG07642.1 - 0.00012 21.3 0.0 0.00019 20.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 KEG07642.1 - 0.0056 15.0 0.0 0.0088 14.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Gp_dh_C PF02800.15 KEG07643.1 - 2.9e-67 225.0 0.2 4e-67 224.5 0.1 1.1 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 KEG07643.1 - 9e-60 201.0 0.1 1.6e-59 200.2 0.1 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 KEG07643.1 - 0.00093 19.1 0.6 0.0057 16.5 0.1 2.4 3 0 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus TgMIC1 PF11476.3 KEG07643.1 - 0.0058 16.1 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Toxoplasma gondii micronemal protein 1 TgMIC1 2-Hacid_dh_C PF02826.14 KEG07643.1 - 0.051 12.7 0.1 0.098 11.8 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aminotran_1_2 PF00155.16 KEG07644.1 - 1.6e-22 79.9 0.0 1.8e-22 79.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Oxysterol_BP PF01237.13 KEG07645.1 - 1.4e-35 122.4 0.0 5.5e-17 61.2 0.0 2.2 2 0 0 2 2 2 2 Oxysterol-binding protein Pentapeptide_4 PF13599.1 KEG07646.1 - 0.00015 21.4 13.4 0.0013 18.5 5.0 2.6 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 KEG07646.1 - 0.0005 19.9 21.6 0.39 10.6 1.7 3.7 3 1 0 4 4 4 3 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 KEG07646.1 - 0.0013 17.8 0.7 0.31 10.3 0.0 3.9 4 0 0 4 4 4 1 Pentapeptide repeats (8 copies) Adeno_E1B_55K PF01696.12 KEG07646.1 - 0.35 9.3 7.2 0.51 8.7 5.0 1.3 1 0 0 1 1 1 0 Adenovirus EB1 55K protein / large t-antigen DAGK_cat PF00781.19 KEG07647.1 - 6.1e-16 58.0 0.0 9.4e-13 47.7 0.0 2.4 2 0 0 2 2 2 2 Diacylglycerol kinase catalytic domain CDC45 PF02724.9 KEG07647.1 - 0.016 13.2 0.3 0.023 12.7 0.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Cep57_MT_bd PF06657.8 KEG07650.1 - 0.018 14.9 9.1 0.023 14.6 4.4 2.6 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Jnk-SapK_ap_N PF09744.4 KEG07650.1 - 0.039 13.9 15.7 0.033 14.1 9.5 1.7 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF445 PF04286.7 KEG07650.1 - 0.042 13.3 4.6 0.058 12.9 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) HET PF06985.6 KEG07650.1 - 0.044 13.9 2.6 0.034 14.3 0.9 1.5 2 0 0 2 2 2 0 Heterokaryon incompatibility protein (HET) Enkurin PF13864.1 KEG07650.1 - 0.066 13.4 12.8 0.61 10.3 7.5 2.5 1 1 1 2 2 2 0 Calmodulin-binding Herpes_UL87 PF03043.9 KEG07650.1 - 0.09 11.1 1.8 0.1 10.9 1.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family Herpes_BBRF1 PF04793.7 KEG07650.1 - 0.27 9.9 1.9 0.47 9.1 1.3 1.4 1 1 0 1 1 1 0 BRRF1-like protein TSC22 PF01166.13 KEG07650.1 - 1.2 9.1 10.8 3.1 7.8 0.0 3.9 3 1 0 4 4 4 0 TSC-22/dip/bun family DUF972 PF06156.8 KEG07650.1 - 2.4 8.5 11.0 13 6.1 4.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF4446 PF14584.1 KEG07650.1 - 2.9 7.6 9.3 2.1 8.1 4.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) GAS PF13851.1 KEG07650.1 - 5.6 6.1 19.1 9.9 5.3 0.1 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding EMP24_GP25L PF01105.19 KEG07650.1 - 6.6 6.4 8.3 7.8 6.1 5.1 1.7 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Sec1 PF00995.18 KEG07651.1 - 3e-117 392.6 0.0 3.6e-117 392.3 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Mucin PF01456.12 KEG07652.1 - 3 7.6 16.7 0.052 13.3 1.0 2.7 2 1 0 2 2 2 0 Mucin-like glycoprotein Collagen PF01391.13 KEG07652.1 - 8.2 6.0 16.6 0.1 12.1 4.7 2.4 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) GRASP55_65 PF04495.9 KEG07653.1 - 1e-47 161.6 0.0 3.7e-32 111.2 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ PF00595.19 KEG07653.1 - 0.00011 22.3 0.0 0.0013 18.8 0.0 2.4 3 0 0 3 3 3 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KEG07653.1 - 0.0096 15.8 0.0 0.027 14.3 0.0 1.7 2 0 0 2 2 2 1 PDZ domain NCA2 PF08637.5 KEG07656.1 - 1.8e-67 227.2 0.9 2.6e-67 226.7 0.6 1.2 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Pkinase PF00069.20 KEG07657.1 - 3e-47 160.9 0.0 3.3e-47 160.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG07657.1 - 1.1e-28 100.0 0.0 1.2e-28 99.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEG07657.1 - 0.028 14.1 0.2 4.7 6.8 0.2 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KEG07657.1 - 0.1 11.5 0.0 0.21 10.5 0.0 1.4 1 1 0 1 1 1 0 Kinase-like EutN_CcmL PF03319.8 KEG07657.1 - 0.14 12.5 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutN/carboxysome DUF2336 PF10098.4 KEG07659.1 - 0.055 12.7 5.7 0.066 12.4 3.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2336) 5_3_exonuc PF01367.15 KEG07659.1 - 0.16 12.2 0.4 0.23 11.6 0.3 1.3 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold PqiA PF04403.8 KEG07661.1 - 2.9e-15 56.2 8.2 2.9e-15 56.2 5.7 2.6 2 1 0 2 2 2 2 Paraquat-inducible protein A Epimerase PF01370.16 KEG07663.1 - 1.1e-40 139.6 0.0 1.5e-40 139.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 KEG07663.1 - 1.4e-13 50.5 0.0 3.7e-13 49.2 0.0 1.7 2 0 0 2 2 2 1 UDP-glucose 4-epimerase C-term subunit Polysacc_synt_2 PF02719.10 KEG07663.1 - 9.2e-13 47.7 0.0 8.1e-12 44.6 0.1 2.0 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 KEG07663.1 - 2.2e-12 46.4 0.0 3.4e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 KEG07663.1 - 3.2e-11 42.4 0.0 7.2e-10 38.0 0.0 2.2 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 KEG07663.1 - 6.2e-08 32.5 0.7 1.3e-07 31.4 0.5 1.5 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 KEG07663.1 - 2.2e-07 30.9 1.3 5.6e-07 29.6 0.9 1.6 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 KEG07663.1 - 4.7e-06 25.7 0.0 4.5e-05 22.4 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KEG07663.1 - 0.014 15.3 0.7 2.7 7.9 0.5 2.3 1 1 0 1 1 1 0 NADH(P)-binding MIase PF02426.11 KEG07663.1 - 0.038 13.8 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 Muconolactone delta-isomerase NmrA PF05368.8 KEG07663.1 - 0.051 12.8 0.1 0.079 12.2 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family PRP21_like_P PF12230.3 KEG07664.1 - 0.012 15.1 0.1 0.083 12.3 0.2 2.0 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein CDC45 PF02724.9 KEG07665.1 - 8e-129 430.4 0.1 9.6e-129 430.2 0.1 1.0 1 0 0 1 1 1 1 CDC45-like protein DUF1168 PF06658.7 KEG07665.1 - 0.0063 16.0 6.8 0.013 15.0 4.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) DUF3449 PF11931.3 KEG07665.1 - 0.061 12.8 2.2 0.11 11.9 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Pox_LP_H2 PF03356.10 KEG07665.1 - 0.16 11.6 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Viral late protein H2 PBP1_TM PF14812.1 KEG07665.1 - 1.9 8.8 11.5 5.3 7.4 8.0 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Herpes_BLLF1 PF05109.8 KEG07667.1 - 1.5 6.6 13.0 1.8 6.4 9.0 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) DUF3533 PF12051.3 KEG07668.1 - 1.4 7.6 4.0 2.1 6.9 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) CENP-K PF11802.3 KEG07668.1 - 1.4 8.0 5.1 0.17 11.0 0.5 1.6 2 0 0 2 2 2 0 Centromere-associated protein K Mucin PF01456.12 KEG07668.1 - 2.9 7.6 54.6 0.096 12.4 11.6 4.2 3 2 0 3 3 3 0 Mucin-like glycoprotein Sec8_exocyst PF04048.9 KEG07668.1 - 7 6.2 9.1 6.2 6.4 0.2 3.0 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain Mucin PF01456.12 KEG07670.1 - 0.0036 17.1 5.5 0.0036 17.1 3.8 3.2 1 1 0 2 2 2 2 Mucin-like glycoprotein DUF4073 PF13285.1 KEG07671.1 - 0.063 12.7 0.0 0.091 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4073) Reo_sigmaC PF04582.7 KEG07672.1 - 0.048 12.8 0.4 0.087 11.9 0.0 1.5 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF4364 PF14277.1 KEG07672.1 - 0.34 10.5 2.1 0.21 11.2 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4364) Bacillus_HBL PF05791.6 KEG07672.1 - 0.49 9.7 6.3 0.17 11.2 0.4 2.0 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) V_ATPase_I PF01496.14 KEG07672.1 - 0.57 7.9 13.7 3.4 5.4 9.5 1.8 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-R PF06729.7 KEG07672.1 - 0.57 9.8 5.8 0.55 9.8 3.4 1.4 1 1 0 1 1 1 0 Kinetochore component, CENP-R Exonuc_VII_L PF02601.10 KEG07672.1 - 0.71 9.0 9.9 0.86 8.7 6.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phage_GP20 PF06810.6 KEG07672.1 - 0.77 9.1 10.4 0.89 8.9 0.8 2.8 1 1 0 2 2 2 0 Phage minor structural protein GP20 DUF1978 PF09321.5 KEG07672.1 - 0.8 9.0 18.5 1.6 8.1 12.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1978) ADIP PF11559.3 KEG07672.1 - 0.87 9.4 24.6 0.058 13.3 5.5 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1675 PF07897.6 KEG07672.1 - 1.8 8.4 8.7 2.5 7.8 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) GAS PF13851.1 KEG07672.1 - 3.6 6.7 20.2 0.71 9.0 5.7 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 KEG07672.1 - 4.6 6.1 17.3 6.1 5.7 12.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 IFP_35_N PF07334.8 KEG07672.1 - 4.8 7.2 13.0 3.9 7.4 0.6 3.2 2 1 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Spc7 PF08317.6 KEG07672.1 - 6.8 5.2 18.0 4.5 5.8 3.9 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein TMCO5 PF14992.1 KEG07672.1 - 7.9 5.5 16.2 12 4.9 11.2 1.2 1 0 0 1 1 1 0 TMCO5 family Allexi_40kDa PF05549.6 KEG07674.1 - 0.074 12.3 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein Pkinase PF00069.20 KEG07675.1 - 5.7e-49 166.6 0.0 1.1e-48 165.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG07675.1 - 3.9e-29 101.5 0.0 6e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG07675.1 - 3.3e-07 29.5 0.0 5.8e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEG07675.1 - 0.028 14.1 1.5 0.095 12.4 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF2937 PF11157.3 KEG07675.1 - 1.6 8.0 4.3 0.34 10.2 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Mcp5_PH PF12814.2 KEG07676.1 - 2.8e-14 53.0 0.0 5.4e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology DUF3395 PF11875.3 KEG07677.1 - 8e-41 139.1 0.0 1.5e-40 138.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 KEG07677.1 - 1e-15 57.1 1.3 1.3e-15 56.8 0.2 1.8 2 0 0 2 2 2 1 DnaJ domain DZR PF12773.2 KEG07678.1 - 0.0031 17.3 2.7 0.052 13.3 0.4 2.9 2 0 0 2 2 2 1 Double zinc ribbon PIF1 PF05970.9 KEG07678.1 - 0.011 14.6 0.2 0.44 9.4 0.0 2.6 2 1 0 2 2 2 0 PIF1-like helicase AAA_30 PF13604.1 KEG07678.1 - 0.058 12.9 0.4 0.1 12.1 0.3 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 KEG07678.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF3505 PF12013.3 KEG07678.1 - 0.12 12.5 6.2 0.18 12.0 0.4 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3505) DUF164 PF02591.10 KEG07678.1 - 0.2 11.5 2.3 0.98 9.2 0.6 2.5 2 0 0 2 2 2 0 Putative zinc ribbon domain Bac_DnaA PF00308.13 KEG07678.1 - 0.22 11.1 0.1 0.96 9.0 0.0 1.9 2 0 0 2 2 2 0 Bacterial dnaA protein Senescence_reg PF04520.8 KEG07681.1 - 0.043 14.3 1.3 0.054 14.0 0.9 1.2 1 0 0 1 1 1 0 Senescence regulator Prp19_bind PF06991.6 KEG07681.1 - 0.076 12.2 0.7 0.091 12.0 0.1 1.4 1 1 0 1 1 1 0 Splicing factor, Prp19-binding domain DUF1193 PF06702.7 KEG07682.1 - 0.0019 17.6 7.9 0.0049 16.3 1.8 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF1193) TRADD_N PF09034.5 KEG07682.1 - 0.005 16.8 2.3 0.005 16.8 1.6 3.4 3 0 0 3 3 3 1 TRADD, N-terminal domain Reo_sigmaC PF04582.7 KEG07682.1 - 0.027 13.6 26.5 0.021 14.0 3.4 4.8 3 1 2 5 5 5 0 Reovirus sigma C capsid protein SNARE_assoc PF09335.6 KEG07685.1 - 6.6e-19 68.3 4.9 6.6e-19 68.3 3.4 2.3 2 0 0 2 2 2 1 SNARE associated Golgi protein Bacteriocin_IIc PF10439.4 KEG07685.1 - 8.8 6.5 6.9 1.7 8.8 1.7 2.1 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Acetyltransf_1 PF00583.19 KEG07686.1 - 8.3e-14 51.3 0.1 1.2e-13 50.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KEG07686.1 - 2.3e-08 34.1 0.3 3e-08 33.8 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KEG07686.1 - 9.1e-07 28.9 0.1 1.2e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEG07686.1 - 3.5e-05 23.4 0.0 5.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 KEG07686.1 - 0.0018 18.0 1.0 0.0031 17.3 0.7 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KEG07686.1 - 0.0021 17.9 0.7 0.0024 17.7 0.5 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KEG07686.1 - 0.0028 17.6 0.0 0.0032 17.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KEG07686.1 - 0.0068 16.5 0.2 0.0084 16.2 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4407 PF14362.1 KEG07687.1 - 0.051 12.5 8.2 0.092 11.6 5.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IncA PF04156.9 KEG07687.1 - 0.064 12.8 10.6 0.13 11.8 7.4 1.5 1 0 0 1 1 1 0 IncA protein NPV_P10 PF05531.7 KEG07687.1 - 0.11 12.7 0.2 0.3 11.3 0.1 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein ATG16 PF08614.6 KEG07687.1 - 0.99 9.1 14.4 0.15 11.8 5.1 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Spc7 PF08317.6 KEG07687.1 - 1.3 7.6 8.3 1.9 7.0 5.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Mucin PF01456.12 KEG07691.1 - 0.00045 20.0 1.2 0.00045 20.0 0.9 4.3 2 1 0 2 2 2 1 Mucin-like glycoprotein Med28 PF11594.3 KEG07691.1 - 0.14 12.4 0.8 0.42 10.8 0.5 1.9 1 1 0 1 1 1 0 Mediator complex subunit 28 DUF677 PF05055.7 KEG07694.1 - 0.15 10.7 0.1 0.19 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) TEX13 PF15186.1 KEG07697.1 - 0.089 12.3 2.7 0.27 10.7 0.2 2.0 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family COX15-CtaA PF02628.10 KEG07700.1 - 6.2e-86 287.9 12.6 7.2e-86 287.7 8.7 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF716 PF04819.7 KEG07700.1 - 0.28 10.6 3.4 0.12 11.7 0.3 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF716) Mak10 PF04112.8 KEG07704.1 - 0.22 10.7 0.0 0.41 9.8 0.0 1.4 1 0 0 1 1 1 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase PHD PF00628.24 KEG07705.1 - 0.01 15.5 6.0 0.025 14.2 4.2 1.7 1 1 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.1 KEG07705.1 - 0.056 13.2 6.3 0.12 12.2 4.4 1.6 1 1 0 1 1 1 0 Ring finger domain Prok-RING_1 PF14446.1 KEG07705.1 - 0.36 10.5 10.7 0.17 11.6 5.9 1.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF2116 PF09889.4 KEG07705.1 - 0.65 9.8 3.9 2.8 7.8 2.0 2.3 2 1 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) C1_1 PF00130.17 KEG07705.1 - 2.4 7.9 5.9 0.19 11.4 0.5 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_2 PF13923.1 KEG07705.1 - 4.9 7.2 8.6 4 7.5 4.9 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ecl1 PF12855.2 KEG07705.1 - 8.7 5.7 12.7 2.7 7.3 5.3 2.5 2 1 0 2 2 2 0 Life-span regulatory factor PI3Ka PF00613.15 KEG07706.1 - 4.5e-48 162.8 0.5 8.2e-48 162.0 0.3 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 KEG07706.1 - 3.2e-39 134.8 0.0 5.3e-39 134.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_rbd PF00794.13 KEG07706.1 - 8.5e-07 28.8 0.0 2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.19 KEG07706.1 - 0.00012 21.8 0.0 0.00029 20.6 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF218 PF02698.12 KEG07707.1 - 0.00075 19.0 0.0 0.0019 17.7 0.0 1.7 1 1 0 1 1 1 1 DUF218 domain FUSC_2 PF13515.1 KEG07710.1 - 1.6e-05 24.7 10.7 1.6e-05 24.7 7.4 2.7 2 1 0 2 2 2 1 Fusaric acid resistance protein-like TPR_12 PF13424.1 KEG07711.1 - 0.00025 20.8 0.3 0.00044 20.1 0.1 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEG07711.1 - 0.00035 20.0 0.3 0.043 13.4 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEG07711.1 - 0.00063 19.3 0.2 0.059 13.1 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEG07711.1 - 0.0035 17.1 3.1 0.13 12.2 0.3 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 KEG07711.1 - 0.0054 16.3 0.1 0.011 15.4 0.1 1.5 1 1 0 1 1 1 1 TPR repeat TPR_14 PF13428.1 KEG07711.1 - 0.0093 16.5 2.1 0.24 12.1 0.3 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat RIB43A PF05914.7 KEG07711.1 - 0.021 13.4 0.1 0.023 13.3 0.1 1.1 1 0 0 1 1 1 0 RIB43A CPG4 PF15481.1 KEG07711.1 - 0.057 13.7 0.4 0.1 12.9 0.3 1.3 1 0 0 1 1 1 0 Chondroitin proteoglycan 4 TPR_7 PF13176.1 KEG07711.1 - 0.1 12.4 1.2 1.3 8.9 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat UIM PF02809.15 KEG07711.1 - 0.32 10.6 2.4 0.34 10.6 0.3 2.1 2 0 0 2 2 2 0 Ubiquitin interaction motif TPR_6 PF13174.1 KEG07711.1 - 0.35 11.4 4.0 2.4 8.8 0.1 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat DNA_repr_REX1B PF14966.1 KEG07712.1 - 0.00058 20.1 0.2 0.0013 19.0 0.1 1.6 1 1 0 1 1 1 1 DNA repair REX1-B DUF2580 PF10824.3 KEG07712.1 - 3.1 8.2 12.5 0.64 10.3 2.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2580) DFP PF04127.10 KEG07713.1 - 7.5e-21 74.5 0.0 2e-10 40.6 0.0 2.1 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein DUF2372 PF10178.4 KEG07714.1 - 0.00033 20.7 0.0 0.00048 20.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2372) Peptidase_M32 PF02074.10 KEG07715.1 - 2.1e-123 412.5 0.0 2.3e-123 412.4 0.0 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase 2OG-FeII_Oxy_2 PF13532.1 KEG07715.1 - 0.034 13.9 0.1 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Vps55 PF04133.9 KEG07716.1 - 2.6e-24 85.2 4.6 3.1e-24 85.0 3.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF4173 PF13777.1 KEG07716.1 - 0.02 14.1 0.5 0.03 13.5 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4173) DUF1469 PF07332.6 KEG07716.1 - 4.6 6.9 10.9 9.6 5.9 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Ribosomal_L7Ae PF01248.21 KEG07717.1 - 6.9e-27 92.8 2.8 2e-22 78.5 0.7 2.1 1 1 1 2 2 2 2 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Lactamase_B_2 PF12706.2 KEG07720.1 - 4.5e-32 111.1 0.1 8e-32 110.3 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 KEG07720.1 - 0.00067 19.0 0.0 0.0018 17.6 0.0 1.7 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 KEG07720.1 - 0.0011 18.6 1.1 0.0042 16.7 0.6 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Pkinase PF00069.20 KEG07723.1 - 3.3e-53 180.4 0.0 4.8e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG07723.1 - 1.5e-35 122.5 0.0 2e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 KEG07723.1 - 4.7e-09 36.3 0.0 8.2e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 KEG07723.1 - 1.4e-08 34.0 0.0 2e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PH_9 PF15410.1 KEG07723.1 - 9e-07 29.0 0.1 3.3e-05 24.0 0.1 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 KEG07723.1 - 0.071 13.3 0.8 2.7 8.2 0.6 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain PH_4 PF15404.1 KEG07723.1 - 0.12 11.8 0.1 1.1 8.7 0.0 1.9 1 1 0 2 2 2 0 Pleckstrin homology domain PH_7 PF15408.1 KEG07723.1 - 0.13 12.1 0.0 0.36 10.7 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain DUF2786 PF10979.3 KEG07728.1 - 0.088 12.5 1.3 1.8 8.3 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) DUF4332 PF14229.1 KEG07728.1 - 0.12 12.3 0.3 0.17 11.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) XPG_I PF00867.13 KEG07731.1 - 1.1e-23 83.1 0.2 1.9e-23 82.2 0.1 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KEG07731.1 - 1.5e-16 60.5 0.0 7e-16 58.3 0.0 2.0 1 1 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 KEG07731.1 - 6.2e-05 22.6 0.1 0.00011 21.8 0.1 1.4 1 0 0 1 1 1 1 XPG domain containing CppA_N PF14506.1 KEG07731.1 - 0.012 15.2 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 CppA N-terminal TPR_11 PF13414.1 KEG07733.1 - 1.1e-06 28.2 0.9 2.2e-06 27.1 0.3 1.7 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 KEG07733.1 - 2.8e-05 23.6 0.7 0.073 13.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KEG07733.1 - 0.0014 18.1 0.1 0.033 13.8 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEG07733.1 - 0.0037 17.9 1.8 0.0051 17.4 0.8 1.6 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 KEG07733.1 - 0.0095 15.8 2.2 0.03 14.2 1.1 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 KEG07733.1 - 2 8.4 4.6 26 4.9 2.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DOT1 PF08123.8 KEG07735.1 - 1.8e-22 79.7 0.0 1.9e-22 79.5 0.0 1.0 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 KEG07735.1 - 2.1e-07 31.4 0.0 2.7e-07 31.1 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEG07735.1 - 1.3e-06 28.0 0.0 2.1e-06 27.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEG07735.1 - 1.3e-05 25.2 0.0 1.4e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEG07735.1 - 8.6e-05 22.9 0.0 0.00016 22.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEG07735.1 - 0.0001 22.5 0.0 0.00014 22.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KEG07735.1 - 0.0018 17.9 0.0 0.002 17.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KEG07735.1 - 0.0036 16.4 0.0 0.005 15.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 KEG07735.1 - 0.008 16.6 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEG07735.1 - 0.025 13.9 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.1 KEG07735.1 - 0.059 13.0 0.0 0.084 12.5 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain AdoMet_MTase PF07757.8 KEG07735.1 - 0.1 12.6 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase MetW PF07021.7 KEG07735.1 - 0.12 11.7 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Isy1 PF06246.7 KEG07736.1 - 1.3e-14 54.1 8.4 4e-13 49.3 5.8 2.5 1 1 0 1 1 1 1 Isy1-like splicing family PRTP PF01366.13 KEG07736.1 - 0.11 10.4 1.1 0.14 10.1 0.8 1.2 1 0 0 1 1 1 0 Herpesvirus processing and transport protein EMP70 PF02990.11 KEG07737.1 - 2.5e-152 508.0 6.0 3.1e-152 507.6 4.1 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 HAUS-augmin3 PF14932.1 KEG07739.1 - 0.3 10.2 5.8 0.063 12.4 0.6 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF3852 PF12963.2 KEG07739.1 - 0.34 10.9 3.6 3.5 7.7 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3852) TBCA PF02970.11 KEG07739.1 - 0.73 9.9 7.2 0.58 10.2 0.2 3.4 4 0 0 4 4 4 0 Tubulin binding cofactor A Mucin PF01456.12 KEG07740.1 - 7.5e-10 38.7 8.1 2.3e-06 27.4 1.8 2.7 2 0 0 2 2 2 2 Mucin-like glycoprotein MGC-24 PF05283.6 KEG07740.1 - 0.012 15.4 2.8 0.012 15.4 2.0 2.6 3 0 0 3 3 3 0 Multi-glycosylated core protein 24 (MGC-24) DUF1874 PF08960.5 KEG07740.1 - 0.095 12.4 0.2 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1874) LAG1-DNAbind PF09271.6 KEG07740.1 - 0.3 11.5 1.5 0.31 11.4 0.0 1.7 2 0 0 2 2 2 0 LAG1, DNA binding DUF2229 PF09989.4 KEG07740.1 - 0.81 9.1 7.5 1.7 8.0 0.5 2.2 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF3813 PF12758.2 KEG07740.1 - 7.1 6.8 7.2 2 8.5 1.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) DUF3359 PF11839.3 KEG07740.1 - 8.3 6.8 30.5 2 8.8 6.6 4.6 4 1 1 5 5 5 0 Protein of unknown function (DUF3359) BCDHK_Adom3 PF10436.4 KEG07741.1 - 0.097 12.1 0.1 8.4 5.8 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase CheZ PF04344.8 KEG07742.1 - 0.0015 18.2 8.9 0.0015 18.2 6.2 2.8 1 1 2 3 3 3 1 Chemotaxis phosphatase, CheZ MGC-24 PF05283.6 KEG07742.1 - 4.4 7.0 14.2 0.31 10.7 3.0 2.3 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) DUF2524 PF10732.4 KEG07742.1 - 4.9 7.3 15.2 2.9 8.0 0.9 3.9 3 2 2 5 5 5 0 Protein of unknown function (DUF2524) Amastin PF07344.6 KEG07743.1 - 9.2e-07 28.5 2.4 9.2e-07 28.5 1.6 1.9 2 0 0 2 2 2 1 Amastin surface glycoprotein Cornichon PF03311.9 KEG07744.1 - 2.2e-15 56.9 4.4 2.2e-15 56.9 3.1 1.5 1 1 0 1 1 1 1 Cornichon protein LRR_6 PF13516.1 KEG07747.1 - 0.028 14.4 0.4 1.3 9.2 0.0 2.9 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.28 KEG07747.1 - 0.037 14.0 0.4 5.6 7.4 0.0 3.6 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_7 PF13504.1 KEG07747.1 - 0.34 11.2 1.4 21 5.8 0.0 3.9 4 0 0 4 4 4 0 Leucine rich repeat Varsurf_PPLC PF03490.8 KEG07749.1 - 7.1e-27 92.8 0.2 1.6e-26 91.6 0.1 1.7 1 0 0 1 1 1 1 Variant-surface-glycoprotein phospholipase C PI-PLC-X PF00388.14 KEG07749.1 - 1.4e-05 24.5 0.0 2.1e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain AAA_2 PF07724.9 KEG07750.1 - 2.8e-57 193.3 0.1 1.8e-55 187.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 KEG07750.1 - 6.9e-27 94.2 0.0 3e-13 50.1 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KEG07750.1 - 2.8e-21 75.1 0.5 8.2e-20 70.5 0.0 3.4 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 KEG07750.1 - 2.4e-16 59.7 0.2 3.7e-11 42.9 0.0 3.7 2 2 1 3 3 3 2 AAA domain (dynein-related subfamily) Clp_N PF02861.15 KEG07750.1 - 2e-15 56.4 2.1 8.6e-08 32.0 0.0 3.4 3 0 0 3 3 2 2 Clp amino terminal domain AAA_16 PF13191.1 KEG07750.1 - 8.5e-11 42.1 5.2 0.0022 18.0 0.0 4.7 3 3 2 5 5 4 2 AAA ATPase domain Sigma54_activat PF00158.21 KEG07750.1 - 1.2e-09 37.8 0.1 1.8e-06 27.4 0.0 3.3 3 2 0 3 3 2 1 Sigma-54 interaction domain AAA_22 PF13401.1 KEG07750.1 - 7.3e-09 35.8 0.8 0.008 16.3 0.0 4.0 3 1 0 3 3 3 2 AAA domain IstB_IS21 PF01695.12 KEG07750.1 - 2.8e-08 33.3 0.0 0.0058 16.0 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 KEG07750.1 - 7.7e-08 32.2 0.0 0.0021 17.9 0.0 3.2 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.7 KEG07750.1 - 1.6e-06 27.4 0.0 0.00068 18.7 0.0 3.8 4 0 0 4 4 4 1 Zeta toxin AAA_17 PF13207.1 KEG07750.1 - 2.9e-06 28.1 5.7 0.0045 17.8 0.0 4.0 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KEG07750.1 - 5.8e-06 25.9 2.9 0.083 12.6 0.0 4.0 4 1 1 5 5 3 2 Part of AAA domain NACHT PF05729.7 KEG07750.1 - 9.2e-06 25.4 0.0 0.039 13.6 0.0 3.4 3 0 0 3 3 3 1 NACHT domain AAA_25 PF13481.1 KEG07750.1 - 3.3e-05 23.3 4.9 0.022 14.1 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.1 KEG07750.1 - 4.9e-05 23.6 0.1 0.22 11.8 0.0 3.4 2 1 1 3 3 2 1 AAA domain Arch_ATPase PF01637.13 KEG07750.1 - 6.9e-05 22.6 6.5 0.93 9.1 0.0 4.7 3 2 1 5 5 5 2 Archaeal ATPase Mg_chelatase PF01078.16 KEG07750.1 - 7.3e-05 22.0 0.0 0.77 8.8 0.0 3.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 KEG07750.1 - 0.00018 20.3 0.0 0.068 11.8 0.0 2.8 2 0 0 2 2 2 1 TIP49 C-terminus AAA_33 PF13671.1 KEG07750.1 - 0.00019 21.3 0.0 0.24 11.2 0.0 4.1 4 0 0 4 4 3 1 AAA domain Bac_DnaA PF00308.13 KEG07750.1 - 0.00025 20.7 0.3 2.8 7.5 0.0 4.3 4 0 0 4 4 4 1 Bacterial dnaA protein RNA_helicase PF00910.17 KEG07750.1 - 0.00026 21.1 0.4 0.78 9.9 0.0 3.5 4 0 0 4 4 2 1 RNA helicase AAA_3 PF07726.6 KEG07750.1 - 0.0003 20.4 0.2 0.18 11.4 0.0 3.6 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 KEG07750.1 - 0.00046 19.2 0.0 1.8 7.4 0.0 3.3 2 1 0 2 2 2 2 Protein of unknown function (DUF815) RuvB_N PF05496.7 KEG07750.1 - 0.00065 18.8 3.1 0.19 10.7 0.0 3.8 3 1 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus T2SE PF00437.15 KEG07750.1 - 0.0015 17.5 0.0 0.011 14.6 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_10 PF12846.2 KEG07750.1 - 0.0015 18.0 2.3 0.61 9.4 0.0 4.0 3 2 1 4 4 4 1 AAA-like domain ABC_tran PF00005.22 KEG07750.1 - 0.0025 18.0 3.3 1.2 9.3 0.0 4.4 5 1 0 5 5 3 1 ABC transporter ResIII PF04851.10 KEG07750.1 - 0.0026 17.6 1.3 0.32 10.7 0.0 3.7 4 1 0 4 4 3 1 Type III restriction enzyme, res subunit AAA_28 PF13521.1 KEG07750.1 - 0.0031 17.5 1.9 1.9 8.4 0.0 4.0 4 1 0 4 4 3 1 AAA domain AAA_29 PF13555.1 KEG07750.1 - 0.0034 16.8 0.0 4.1 7.0 0.0 2.9 3 0 0 3 3 2 0 P-loop containing region of AAA domain DnaB_C PF03796.10 KEG07750.1 - 0.0036 16.2 0.0 0.1 11.4 0.0 2.5 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain DUF258 PF03193.11 KEG07750.1 - 0.0039 16.4 0.0 3.2 6.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 IncA PF04156.9 KEG07750.1 - 0.004 16.7 13.8 0.004 16.7 9.6 2.0 2 0 0 2 2 2 1 IncA protein NTPase_1 PF03266.10 KEG07750.1 - 0.0069 16.1 0.5 5 6.7 0.0 3.4 4 0 0 4 4 2 0 NTPase MobB PF03205.9 KEG07750.1 - 0.01 15.5 0.0 1 9.0 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 KEG07750.1 - 0.012 15.2 0.1 8.8 5.9 0.0 3.0 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 DNA_pol3_delta2 PF13177.1 KEG07750.1 - 0.014 15.0 0.1 0.36 10.4 0.0 3.0 3 2 0 3 3 1 0 DNA polymerase III, delta subunit Apc5 PF12862.2 KEG07750.1 - 0.051 13.4 0.4 2.4 8.0 0.1 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 AAA_23 PF13476.1 KEG07750.1 - 0.063 13.6 18.9 1.3 9.3 0.0 4.2 3 1 0 3 3 2 0 AAA domain Miro PF08477.8 KEG07750.1 - 0.063 13.7 0.0 6.5 7.2 0.0 2.9 2 0 0 2 2 2 0 Miro-like protein MMR_HSR1 PF01926.18 KEG07750.1 - 0.076 12.9 0.0 3.3 7.6 0.0 2.9 3 0 0 3 3 2 0 50S ribosome-binding GTPase APG6 PF04111.7 KEG07750.1 - 0.12 11.3 7.7 0.67 8.9 5.7 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 AAA_13 PF13166.1 KEG07750.1 - 0.27 9.6 8.7 0.43 8.9 6.0 1.2 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 KEG07750.1 - 0.47 8.2 6.1 0.73 7.6 4.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HAUS-augmin3 PF14932.1 KEG07750.1 - 0.51 9.4 11.3 1.2 8.2 7.5 1.9 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF87 PF01935.12 KEG07750.1 - 0.63 9.8 6.7 1.1 9.0 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function DUF87 Macoilin PF09726.4 KEG07750.1 - 0.69 8.1 10.4 1.2 7.3 7.2 1.3 1 0 0 1 1 1 0 Transmembrane protein Prominin PF05478.6 KEG07750.1 - 0.78 7.1 2.3 1.2 6.5 1.6 1.2 1 0 0 1 1 1 0 Prominin NPV_P10 PF05531.7 KEG07750.1 - 7.2 6.9 9.7 3.3 8.0 2.3 3.3 3 1 0 3 3 1 0 Nucleopolyhedrovirus P10 protein DUF3149 PF11346.3 KEG07751.1 - 0.026 14.0 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) WD40 PF00400.27 KEG07752.1 - 2.6e-44 147.5 17.8 4.4e-12 45.3 0.1 7.4 7 1 1 8 8 8 6 WD domain, G-beta repeat eIF2A PF08662.6 KEG07752.1 - 9.3e-09 35.2 0.0 0.00011 21.9 0.0 3.4 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Tad_C PF09977.4 KEG07752.1 - 0.098 13.6 0.1 0.45 11.5 0.0 2.2 1 1 1 2 2 2 0 Putative Tad-like Flp pilus-assembly DUF3312 PF11768.3 KEG07752.1 - 0.19 9.9 0.0 0.34 9.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) PAP2 PF01569.16 KEG07753.1 - 2.9e-19 69.0 2.3 2.9e-19 69.0 1.6 1.5 2 0 0 2 2 2 1 PAP2 superfamily ATP_synt_I PF03899.10 KEG07753.1 - 2.1 8.5 9.3 5 7.3 1.8 2.5 2 0 0 2 2 2 0 ATP synthase I chain Abhydrolase_5 PF12695.2 KEG07754.1 - 1.5e-15 57.1 0.5 3e-15 56.2 0.4 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEG07754.1 - 1.8e-12 47.6 0.3 2.9e-12 46.9 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KEG07754.1 - 5.1e-11 42.5 0.0 6e-09 35.7 0.0 2.2 1 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 KEG07754.1 - 1.3e-06 27.8 0.0 9.2e-06 25.0 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.7 KEG07754.1 - 1.7e-06 26.7 0.0 0.00052 18.6 0.0 2.3 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.15 KEG07754.1 - 7.3e-06 25.7 0.5 0.00013 21.5 0.1 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KEG07754.1 - 5.1e-05 23.0 0.1 0.0001 22.0 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase BAAT_C PF08840.6 KEG07754.1 - 0.0055 16.4 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal PhoPQ_related PF10142.4 KEG07754.1 - 0.015 13.7 0.0 0.019 13.4 0.0 1.3 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Esterase PF00756.15 KEG07754.1 - 0.016 14.6 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Putative esterase FSH1 PF03959.8 KEG07754.1 - 0.024 14.0 0.1 0.024 14.0 0.0 1.9 2 1 0 2 2 2 0 Serine hydrolase (FSH1) DUF4637 PF15470.1 KEG07754.1 - 0.076 12.6 2.5 0.13 11.9 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DLH PF01738.13 KEG07754.1 - 0.11 11.7 0.2 5.5 6.2 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family RabGAP-TBC PF00566.13 KEG07755.1 - 3.4e-52 177.0 0.0 4.5e-52 176.6 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF330 PF03886.8 KEG07755.1 - 0.035 13.5 0.1 0.15 11.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF330) PP2C PF00481.16 KEG07756.1 - 3.8e-46 157.5 0.1 4.7e-46 157.2 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KEG07756.1 - 2e-06 27.6 0.0 1.9e-05 24.4 0.0 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 KEG07756.1 - 0.0053 16.1 0.0 0.016 14.6 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C BCS1_N PF08740.6 KEG07758.1 - 9.1e-42 142.7 3.6 1.4e-41 142.2 2.5 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 KEG07758.1 - 3.1e-18 66.2 0.0 9.5e-18 64.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KEG07758.1 - 0.0041 17.9 0.0 0.0094 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KEG07758.1 - 0.0061 16.7 0.0 0.054 13.6 0.0 2.3 2 0 0 2 2 2 1 RNA helicase DUF815 PF05673.8 KEG07758.1 - 0.0065 15.4 0.0 0.013 14.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 KEG07758.1 - 0.009 15.8 0.1 0.032 14.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEG07758.1 - 0.013 15.4 3.8 0.12 12.3 2.6 2.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.9 KEG07758.1 - 0.014 15.0 0.1 0.059 13.0 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KEG07758.1 - 0.022 13.7 0.0 0.084 11.9 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus ABC_tran PF00005.22 KEG07758.1 - 0.024 14.9 0.0 0.094 13.0 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.1 KEG07758.1 - 0.036 13.4 0.0 0.14 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KEG07758.1 - 0.039 13.6 0.0 0.36 10.4 0.0 2.3 1 1 1 2 2 2 0 NACHT domain Rad17 PF03215.10 KEG07758.1 - 0.042 12.5 0.0 0.15 10.7 0.0 1.7 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 KEG07758.1 - 0.044 13.5 0.1 0.38 10.5 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain AAA_22 PF13401.1 KEG07758.1 - 0.065 13.3 0.0 0.24 11.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.1 KEG07758.1 - 0.11 12.0 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain zf-C3HC4_3 PF13920.1 KEG07760.1 - 5.8e-12 45.0 14.0 8e-12 44.6 9.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEG07760.1 - 4.1e-05 23.5 17.1 6.1e-05 22.9 11.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEG07760.1 - 0.0012 18.4 15.1 0.0018 17.9 10.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.1 KEG07760.1 - 0.12 11.9 8.6 0.23 11.0 6.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-met2 PF12907.2 KEG07761.1 - 1.6e-06 28.0 0.8 2e-06 27.6 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding 4F5 PF04419.9 KEG07761.1 - 0.006 17.2 9.5 0.006 17.2 6.6 1.6 2 0 0 2 2 2 1 4F5 protein family zf-Di19 PF05605.7 KEG07761.1 - 0.033 14.2 0.4 0.05 13.7 0.3 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 KEG07761.1 - 0.056 13.7 2.5 0.17 12.3 0.2 2.3 2 1 0 2 2 2 0 C2H2-type zinc finger Isochorismatase PF00857.15 KEG07762.1 - 4.6e-13 49.4 0.7 2.1e-12 47.3 0.5 1.8 1 1 0 1 1 1 1 Isochorismatase family GPS PF01825.16 KEG07762.1 - 0.036 14.1 0.4 0.58 10.3 0.1 2.5 2 0 0 2 2 2 0 Latrophilin/CL-1-like GPS domain DUF1152 PF06626.7 KEG07763.1 - 0.12 11.5 0.0 0.12 11.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1152) Inositol_P PF00459.20 KEG07765.1 - 9.1e-24 84.1 0.0 1.8e-23 83.2 0.0 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family PPE PF00823.14 KEG07765.1 - 0.082 12.7 0.6 0.15 11.8 0.1 1.6 2 0 0 2 2 2 0 PPE family DUF4588 PF15251.1 KEG07766.1 - 0.0019 18.2 2.6 0.032 14.2 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4588) Hairy_orange PF07527.8 KEG07766.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Hairy Orange RIIa PF02197.12 KEG07767.1 - 0.066 12.6 0.2 0.13 11.6 0.1 1.5 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit DivIC PF04977.10 KEG07767.1 - 0.081 12.4 0.6 1.6 8.2 0.1 2.1 2 0 0 2 2 2 0 Septum formation initiator Nup54 PF13874.1 KEG07768.1 - 2.8e-32 111.3 1.6 2.8e-32 111.3 1.1 1.5 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 DUF1875 PF08961.5 KEG07768.1 - 0.0003 20.1 0.1 0.00043 19.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1875) DUF1235 PF06822.7 KEG07768.1 - 0.024 13.6 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1235) Mad3_BUB1_I PF08311.7 KEG07768.1 - 0.029 14.1 0.1 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 FliD_N PF02465.13 KEG07768.1 - 0.068 13.5 0.2 4.2 7.8 0.0 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus ABC_tran_2 PF12848.2 KEG07768.1 - 0.91 9.4 4.2 1.8 8.4 2.9 1.5 1 0 0 1 1 1 0 ABC transporter PQQ_3 PF13570.1 KEG07769.1 - 0.069 13.4 0.0 0.25 11.6 0.0 2.0 2 0 0 2 2 2 0 PQQ-like domain V-SNARE_C PF12352.3 KEG07771.1 - 7.2e-05 22.7 3.3 7.2e-05 22.7 2.3 2.6 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Latarcin PF10279.4 KEG07771.1 - 0.0073 16.4 0.9 0.024 14.8 0.3 2.0 2 1 0 2 2 2 1 Latarcin precursor Acyl-CoA_dh_C PF12806.2 KEG07771.1 - 0.069 13.0 4.2 0.24 11.2 0.8 2.5 1 1 0 2 2 2 0 Acetyl-CoA dehydrogenase C-terminal like Sec20 PF03908.8 KEG07771.1 - 0.071 12.8 0.3 0.24 11.1 0.0 2.0 2 0 0 2 2 2 0 Sec20 FlgN PF05130.7 KEG07771.1 - 0.13 12.4 12.4 0.032 14.4 4.4 2.5 1 1 0 2 2 2 0 FlgN protein Peptidase_M14 PF00246.19 KEG07772.1 - 4.2e-27 95.4 0.0 7.3e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.9 KEG07772.1 - 0.00011 21.1 0.1 0.00019 20.4 0.0 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Aa_trans PF01490.13 KEG07774.1 - 9e-66 222.0 23.8 1.1e-65 221.7 16.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KEG07774.1 - 2e-08 33.5 8.8 2e-08 33.5 6.1 2.5 1 1 2 3 3 3 1 Tryptophan/tyrosine permease family AA_permease_2 PF13520.1 KEG07774.1 - 0.0011 17.5 27.6 0.019 13.5 19.1 2.0 1 1 0 1 1 1 1 Amino acid permease FIBP PF05427.6 KEG07777.1 - 4e-08 32.9 0.2 0.00043 19.6 0.1 3.0 3 0 0 3 3 3 3 Acidic fibroblast growth factor binding (FIBP) Rpr2 PF04032.11 KEG07778.1 - 0.093 12.6 0.8 0.17 11.7 0.2 1.8 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain PCMT PF01135.14 KEG07780.1 - 7.5e-57 192.2 0.0 9e-57 191.9 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 KEG07780.1 - 3.6e-12 46.8 0.0 6e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEG07780.1 - 1.9e-10 40.5 0.0 2.5e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEG07780.1 - 2.8e-08 33.7 0.1 1.2e-07 31.8 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KEG07780.1 - 3.7e-08 33.1 0.0 6e-08 32.4 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEG07780.1 - 1.4e-06 28.1 0.0 2.7e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 KEG07780.1 - 5.2e-06 27.2 0.0 1.4e-05 25.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEG07780.1 - 6.3e-06 26.5 0.0 1.6e-05 25.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEG07780.1 - 3.3e-05 23.1 0.0 4.8e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 KEG07780.1 - 5.3e-05 22.3 0.0 7.9e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.9 KEG07780.1 - 0.00052 19.4 0.0 0.00099 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KEG07780.1 - 0.001 19.3 0.0 0.0019 18.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 KEG07780.1 - 0.0021 17.1 0.0 0.0028 16.7 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase N6_N4_Mtase PF01555.13 KEG07780.1 - 0.0052 16.2 0.0 0.23 10.8 0.0 2.1 2 0 0 2 2 2 1 DNA methylase Methyltransf_12 PF08242.7 KEG07780.1 - 0.0071 16.7 0.0 0.018 15.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Rsm22 PF09243.5 KEG07780.1 - 0.0097 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 FtsJ PF01728.14 KEG07780.1 - 0.015 15.2 0.0 0.042 13.8 0.0 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 KEG07780.1 - 0.016 14.2 0.0 0.031 13.3 0.0 1.4 2 0 0 2 2 1 0 Putative methyltransferase PrmA PF06325.8 KEG07780.1 - 0.021 13.9 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 KEG07780.1 - 0.093 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW GidB PF02527.10 KEG07780.1 - 0.14 11.2 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Fibrillarin PF01269.12 KEG07780.1 - 0.17 10.7 0.0 0.34 9.7 0.0 1.5 1 0 0 1 1 1 0 Fibrillarin Myb_DNA-binding PF00249.26 KEG07781.1 - 3.7e-07 30.0 0.3 8.7e-07 28.9 0.0 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KEG07781.1 - 0.0027 17.7 0.1 0.0027 17.7 0.1 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Gag_p17 PF00540.13 KEG07782.1 - 0.0024 17.6 2.7 0.42 10.3 0.3 2.7 2 0 0 2 2 2 2 gag gene protein p17 (matrix protein) DUF972 PF06156.8 KEG07782.1 - 0.23 11.8 1.7 13 6.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Taxilin PF09728.4 KEG07782.1 - 0.66 9.0 5.2 0.12 11.3 1.2 1.5 2 0 0 2 2 2 0 Myosin-like coiled-coil protein Intg_mem_TP0381 PF09529.5 KEG07783.1 - 0.012 14.8 5.6 0.016 14.4 3.9 1.1 1 0 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) Bax1-I PF01027.15 KEG07783.1 - 0.076 12.6 6.1 0.096 12.2 4.2 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 FA_desaturase PF00487.19 KEG07783.1 - 0.18 11.1 10.3 0.21 10.9 7.1 1.1 1 0 0 1 1 1 0 Fatty acid desaturase Cation_ATPase_C PF00689.16 KEG07783.1 - 7.4 6.0 9.8 49 3.3 6.2 2.3 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus RRM_5 PF13893.1 KEG07784.1 - 0.067 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4456 PF14644.1 KEG07788.1 - 1.6e-22 79.7 0.0 1.6e-22 79.7 0.0 3.5 4 1 0 4 4 4 1 Domain of unknown function (DUF4456) NAM-associated PF14303.1 KEG07790.1 - 3.6 7.8 9.7 0.14 12.4 2.3 1.9 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain DUF2215 PF10225.4 KEG07792.1 - 0.0084 15.5 1.5 0.012 15.0 0.9 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2215) Nodulin-like PF06813.8 KEG07793.1 - 5.5e-07 29.1 5.3 5.5e-07 29.1 3.7 2.6 3 0 0 3 3 3 1 Nodulin-like DUF2516 PF10724.4 KEG07793.1 - 0.25 11.3 5.6 7.2 6.6 0.0 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF2516) Nodulin-like PF06813.8 KEG07794.1 - 9.7e-12 44.6 6.2 9.7e-12 44.6 4.3 2.6 2 0 0 2 2 2 2 Nodulin-like zf-CW PF07496.10 KEG07795.1 - 0.00033 20.3 7.9 0.0007 19.2 5.4 1.6 1 0 0 1 1 1 1 CW-type Zinc Finger SSP160 PF06933.6 KEG07795.1 - 0.032 12.2 4.2 0.043 11.8 2.9 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Fer4_18 PF13746.1 KEG07795.1 - 0.21 12.0 0.2 0.21 12.0 0.1 3.3 2 1 0 2 2 2 0 4Fe-4S dicluster domain Macoilin PF09726.4 KEG07795.1 - 1.3 7.2 16.8 1.8 6.7 11.6 1.2 1 0 0 1 1 1 0 Transmembrane protein RAP1 PF07218.6 KEG07795.1 - 8.8 4.2 14.8 12 3.8 10.3 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) IL17 PF06083.6 KEG07797.1 - 0.086 12.9 0.6 0.7 9.9 0.2 2.0 2 0 0 2 2 2 0 Interleukin-17 GTP_EFTU PF00009.22 KEG07798.1 - 6.3e-55 185.5 0.1 1.2e-54 184.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KEG07798.1 - 1.9e-36 124.1 0.2 1.1e-35 121.7 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KEG07798.1 - 3.1e-18 65.6 0.8 3.1e-18 65.6 0.6 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 KEG07798.1 - 2e-05 24.1 0.7 6.6e-05 22.4 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 KEG07798.1 - 0.00044 20.1 0.1 0.0016 18.3 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase FlpD PF02662.11 KEG07798.1 - 0.0082 15.8 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 1 Methyl-viologen-reducing hydrogenase, delta subunit Semialdhyde_dhC PF02774.13 KEG07798.1 - 0.016 15.0 0.3 0.12 12.1 0.1 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain Miro PF08477.8 KEG07798.1 - 0.059 13.8 0.2 0.63 10.5 0.2 2.3 1 1 0 1 1 1 0 Miro-like protein RBD PF02196.10 KEG07801.1 - 0.04 13.6 0.1 0.095 12.4 0.1 1.6 1 0 0 1 1 1 0 Raf-like Ras-binding domain LRR_4 PF12799.2 KEG07801.1 - 0.25 10.9 0.7 14 5.4 0.1 2.4 1 1 0 2 2 2 0 Leucine Rich repeats (2 copies) LEA_1 PF03760.10 KEG07802.1 - 0.018 15.1 1.2 0.018 15.1 0.8 2.3 3 0 0 3 3 3 0 Late embryogenesis abundant (LEA) group 1 AP-5_subunit_s1 PF15001.1 KEG07802.1 - 0.34 10.8 0.0 0.34 10.8 0.0 2.1 2 1 0 2 2 2 0 AP-5 complex subunit sigma-1 SNase PF00565.12 KEG07803.1 - 1.3e-20 73.6 0.0 1.9e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue DUF1743 PF08489.6 KEG07803.1 - 0.083 12.6 0.0 0.26 11.0 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1743) SNase PF00565.12 KEG07804.1 - 1.5e-12 47.6 0.0 2.5e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue cNMP_binding PF00027.24 KEG07808.1 - 8.5e-16 57.5 0.0 6.2e-05 22.7 0.0 4.1 3 1 0 3 3 3 3 Cyclic nucleotide-binding domain Fer4_NifH PF00142.13 KEG07809.1 - 0.09 11.9 0.0 0.098 11.8 0.0 1.1 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Exo_endo_phos_2 PF14529.1 KEG07810.1 - 3.9e-13 49.0 0.0 7.2e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Guanylate_cyc PF00211.15 KEG07812.1 - 1.4e-21 76.7 0.0 1.9e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain GAS PF13851.1 KEG07814.1 - 0.06 12.5 5.4 0.1 11.8 3.7 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 KEG07814.1 - 0.098 12.2 8.7 0.17 11.4 6.0 1.3 1 0 0 1 1 1 0 IncA protein BRF1 PF07741.8 KEG07814.1 - 0.36 11.0 3.6 0.78 9.9 2.5 1.5 1 0 0 1 1 1 0 Brf1-like TBP-binding domain AAA_32 PF13654.1 KEG07814.1 - 0.61 8.6 8.2 0.9 8.1 5.7 1.1 1 0 0 1 1 1 0 AAA domain Phage_GPO PF05929.6 KEG07814.1 - 1.1 8.4 5.8 1.7 7.8 4.0 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase IncA PF04156.9 KEG07817.1 - 0.7 9.4 9.8 1.9 8.0 5.0 2.3 2 0 0 2 2 2 0 IncA protein DEAD PF00270.24 KEG07818.1 - 2.9e-45 153.8 0.0 1.3e-44 151.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEG07818.1 - 1e-24 86.1 0.0 2.3e-24 85.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEG07818.1 - 0.003 17.4 0.0 0.015 15.1 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KEG07818.1 - 0.0057 16.2 0.0 0.082 12.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain HAD_2 PF13419.1 KEG07819.1 - 3.3e-12 46.9 0.0 4.3e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KEG07819.1 - 0.048 13.3 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like DUF2608 PF11019.3 KEG07819.1 - 0.11 11.4 0.0 0.95 8.4 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2608) EMP24_GP25L PF01105.19 KEG07820.1 - 9.4e-26 90.6 0.0 1.2e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Cep57_MT_bd PF06657.8 KEG07820.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DUF3753 PF12575.3 KEG07820.1 - 0.22 11.3 0.1 0.22 11.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) HAMP PF00672.20 KEG07820.1 - 0.84 9.8 0.1 0.84 9.8 0.0 3.0 3 0 0 3 3 3 0 HAMP domain PsiA PF06952.6 KEG07822.1 - 0.032 13.2 0.1 0.051 12.6 0.0 1.2 1 0 0 1 1 1 0 PsiA protein UEV PF05743.8 KEG07823.1 - 1.1e-14 54.1 0.0 7.2e-14 51.5 0.0 1.9 2 0 0 2 2 2 1 UEV domain zf-C3HC4_3 PF13920.1 KEG07823.1 - 4e-11 42.4 7.8 1e-10 41.0 5.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UQ_con PF00179.21 KEG07823.1 - 0.025 13.9 0.3 0.13 11.6 0.0 2.0 1 1 1 2 2 2 0 Ubiquitin-conjugating enzyme zf-RING_2 PF13639.1 KEG07823.1 - 0.03 14.1 9.5 0.12 12.2 6.6 2.1 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.1 KEG07823.1 - 0.47 10.0 5.8 2 8.0 4.0 2.1 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RNase_H PF00075.19 KEG07827.1 - 6.9e-06 26.4 0.0 1.4e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 RNase H zf-C2H2_4 PF13894.1 KEG07827.1 - 6.6 7.3 11.1 2.8 8.4 1.3 3.3 2 1 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KEG07828.1 - 0.16 12.1 0.8 6 7.0 0.1 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 KEG07828.1 - 2.5 8.2 6.0 0.35 11.0 0.3 2.3 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding ELO PF01151.13 KEG07829.1 - 3.4e-68 229.6 20.2 3.9e-68 229.4 14.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Bestrophin PF01062.16 KEG07829.1 - 0.024 13.6 7.1 0.049 12.5 4.9 1.5 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel ELO PF01151.13 KEG07830.1 - 3.7e-79 265.5 14.8 4.4e-79 265.3 10.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.13 KEG07831.1 - 7.7e-67 225.2 9.6 9.1e-67 224.9 6.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family SET PF00856.23 KEG07832.1 - 3.4e-35 121.7 6.8 9.5e-05 22.7 0.1 11.3 10 2 2 12 12 12 5 SET domain SAF PF08666.7 KEG07832.1 - 1.3e-08 35.1 0.0 24 5.4 0.0 8.8 9 1 0 9 9 9 2 SAF domain PS_Dcarbxylase PF02666.10 KEG07833.1 - 5.5e-39 133.5 0.0 6.7e-39 133.2 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Peptidase_M23 PF01551.17 KEG07833.1 - 0.015 15.3 0.1 1.2 9.1 0.0 2.6 3 0 0 3 3 3 0 Peptidase family M23 Biotin_lipoyl_2 PF13533.1 KEG07833.1 - 0.18 11.5 0.6 0.55 9.9 0.0 2.0 2 0 0 2 2 2 0 Biotin-lipoyl like AAA_13 PF13166.1 KEG07834.1 - 0.016 13.7 19.2 0.8 8.0 11.4 2.3 2 1 0 2 2 2 0 AAA domain CotH PF08757.6 KEG07834.1 - 0.82 8.8 9.7 0.051 12.8 2.1 2.1 3 0 0 3 3 3 0 CotH protein Tropomyosin_1 PF12718.2 KEG07834.1 - 0.87 9.4 36.7 0.27 11.0 0.5 3.2 3 1 0 3 3 3 0 Tropomyosin like DUF4201 PF13870.1 KEG07834.1 - 1.4 8.3 34.3 2.7 7.3 0.8 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4201) Seryl_tRNA_N PF02403.17 KEG07834.1 - 3 7.8 37.0 0.78 9.7 10.9 4.1 2 1 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 KEG07834.1 - 6.6 6.2 43.4 4.5 6.8 20.2 3.3 1 1 2 3 3 3 0 IncA protein DUF2681 PF10883.3 KEG07834.1 - 7.3 6.8 17.5 0.19 11.9 6.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2681) TraF_2 PF13729.1 KEG07834.1 - 9.3 4.9 6.7 3.7 6.2 0.1 2.9 3 1 1 4 4 4 0 F plasmid transfer operon, TraF, protein tRNA_bind PF01588.15 KEG07836.1 - 8.6e-28 96.0 0.0 1.7e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain Dynamin_N PF00350.18 KEG07837.1 - 6.1e-18 65.1 0.0 3.8e-17 62.6 0.0 2.0 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 KEG07837.1 - 2.7e-08 33.7 0.0 7.3e-08 32.3 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KEG07837.1 - 3.3e-05 24.3 0.0 0.015 15.7 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein AAA_33 PF13671.1 KEG07837.1 - 6.6e-05 22.8 0.1 0.59 9.9 0.0 3.4 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 KEG07837.1 - 0.0024 17.1 0.0 0.043 13.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KEG07837.1 - 0.0026 17.2 0.0 0.21 10.9 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KEG07837.1 - 0.025 13.8 0.0 1.2 8.4 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B ABC_tran PF00005.22 KEG07837.1 - 0.028 14.7 0.0 0.22 11.8 0.0 2.4 3 0 0 3 3 3 0 ABC transporter Septin PF00735.13 KEG07837.1 - 0.16 10.9 0.0 0.3 10.0 0.0 1.4 1 0 0 1 1 1 0 Septin WD40 PF00400.27 KEG07838.1 - 6.3e-13 48.0 10.3 0.0045 16.8 0.1 7.1 8 0 0 8 8 8 4 WD domain, G-beta repeat PQQ_3 PF13570.1 KEG07838.1 - 0.0015 18.7 7.8 4.4 7.7 0.1 5.7 5 0 0 5 5 5 2 PQQ-like domain BBS2_Mid PF14783.1 KEG07838.1 - 0.0074 16.0 0.1 0.47 10.2 0.0 3.7 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.1 KEG07838.1 - 0.01 15.2 0.2 0.79 9.1 0.0 3.0 3 0 0 3 3 3 0 PQQ-like domain DUF3312 PF11768.3 KEG07838.1 - 0.042 12.0 0.0 19 3.2 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3312) Cullin PF00888.17 KEG07843.1 - 2.4e-55 188.2 0.0 4e-55 187.4 0.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KEG07843.1 - 2.1e-18 65.9 0.2 4.6e-18 64.8 0.1 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain Exotox-A_target PF09102.5 KEG07843.1 - 0.043 13.3 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 Exotoxin A, targeting PIG-H PF10181.4 KEG07844.1 - 5.7e-14 51.4 0.1 8.7e-14 50.9 0.0 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component ERCC4 PF02732.10 KEG07845.1 - 7.8e-17 61.3 0.0 7.8e-16 58.1 0.0 2.4 2 0 0 2 2 2 1 ERCC4 domain EF-hand_6 PF13405.1 KEG07846.1 - 0.094 12.6 0.0 0.61 10.1 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.1 KEG07846.1 - 0.12 12.5 0.0 0.56 10.3 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain pair O-FucT PF10250.4 KEG07848.1 - 0.00088 18.4 0.3 0.0019 17.4 0.2 1.7 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase JAB PF01398.16 KEG07848.1 - 0.083 12.6 0.0 2.3 7.9 0.1 2.3 2 0 0 2 2 2 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF2036 PF09724.4 KEG07852.1 - 2e-56 191.4 0.0 2.4e-56 191.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) BAG PF02179.11 KEG07853.1 - 0.021 14.9 1.1 0.021 14.9 0.7 1.8 2 0 0 2 2 2 0 BAG domain Med15 PF09606.5 KEG07853.1 - 0.24 9.5 59.4 0.32 9.1 41.2 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Nic96 PF04097.9 KEG07855.1 - 8.8e-104 347.8 0.0 1.1e-103 347.5 0.0 1.0 1 0 0 1 1 1 1 Nup93/Nic96 TPR_4 PF07721.9 KEG07855.1 - 0.5 10.9 6.3 11 6.7 2.9 3.6 2 0 0 2 2 2 0 Tetratricopeptide repeat SNAPc_SNAP43 PF09808.4 KEG07856.1 - 2.6e-05 23.9 0.0 4.1e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 DEAD PF00270.24 KEG07857.1 - 4.5e-27 94.6 0.0 8.4e-27 93.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEG07857.1 - 9.3e-17 60.6 0.0 2e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 KEG07857.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain AOX PF01786.12 KEG07858.1 - 8e-88 293.2 0.9 6.5e-63 211.8 0.2 2.2 1 1 1 2 2 2 2 Alternative oxidase HSP90 PF00183.13 KEG07859.1 - 3.9e-261 867.0 31.7 4.6e-261 866.8 21.9 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 KEG07859.1 - 7.1e-12 45.0 0.0 1.4e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KEG07859.1 - 2.2e-11 43.5 0.1 2.2e-11 43.5 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1510 PF07423.6 KEG07859.1 - 1.3 8.3 21.6 0.04 13.2 8.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) ABC_tran PF00005.22 KEG07860.1 - 4.4e-43 146.8 1.8 1.6e-20 73.8 0.0 3.8 4 0 0 4 4 4 2 ABC transporter AAA_21 PF13304.1 KEG07860.1 - 4.6e-18 66.1 0.2 0.00037 20.5 0.0 4.3 3 1 0 4 4 4 4 AAA domain SMC_N PF02463.14 KEG07860.1 - 8.1e-14 51.3 0.2 5.4e-05 22.5 0.0 4.1 3 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 KEG07860.1 - 1.7e-07 30.5 0.2 0.0046 16.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 KEG07860.1 - 6.1e-07 28.8 0.3 0.04 13.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.1 KEG07860.1 - 3.8e-05 23.5 0.5 0.028 14.3 0.0 4.0 3 2 0 3 3 3 1 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 KEG07860.1 - 5.1e-05 24.0 4.6 0.056 14.2 0.0 4.2 4 1 0 4 4 4 1 AAA domain MMR_HSR1 PF01926.18 KEG07860.1 - 0.00099 19.0 0.1 0.21 11.5 0.1 3.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KEG07860.1 - 0.0017 18.5 0.1 1.1 9.3 0.1 2.9 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KEG07860.1 - 0.0025 17.9 0.0 0.62 10.2 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.1 KEG07860.1 - 0.003 17.4 0.0 4.2 7.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 KEG07860.1 - 0.0051 15.9 4.3 4.6 6.1 0.0 4.7 5 0 0 5 5 5 1 AAA ATPase domain AAA_16 PF13191.1 KEG07860.1 - 0.0072 16.3 0.8 1.2 9.0 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain ABC_tran_2 PF12848.2 KEG07860.1 - 0.0075 16.0 0.4 0.0075 16.0 0.3 3.7 3 1 0 3 3 2 1 ABC transporter AAA PF00004.24 KEG07860.1 - 0.011 15.9 0.2 9.4 6.4 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 KEG07860.1 - 0.011 15.2 0.1 1.1 8.5 0.1 3.2 3 0 0 3 3 3 0 AAA-like domain AAA_28 PF13521.1 KEG07860.1 - 0.019 14.9 0.1 11 5.9 0.0 3.0 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 KEG07860.1 - 0.02 13.6 0.1 2.4 6.8 0.0 2.7 2 0 0 2 2 2 0 ArgK protein Miro PF08477.8 KEG07860.1 - 0.031 14.7 0.0 2.1 8.8 0.0 2.9 2 0 0 2 2 2 0 Miro-like protein AAA_33 PF13671.1 KEG07860.1 - 0.041 13.7 0.0 2.4 8.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain Hemerythrin PF01814.18 KEG07860.1 - 0.06 13.5 0.1 0.06 13.5 0.0 2.9 4 0 0 4 4 3 0 Hemerythrin HHE cation binding domain NACHT PF05729.7 KEG07860.1 - 0.06 13.0 0.4 4.2 7.0 0.0 3.0 3 0 0 3 3 3 0 NACHT domain AAA_23 PF13476.1 KEG07860.1 - 1.3 9.2 0.0 1.3 9.2 0.0 4.9 5 1 0 5 5 4 0 AAA domain AAA_18 PF13238.1 KEG07860.1 - 2 8.7 9.8 5.9 7.2 0.0 3.9 4 0 0 4 4 3 0 AAA domain Pkinase PF00069.20 KEG07861.1 - 1.1e-48 165.6 0.0 8.3e-38 130.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEG07861.1 - 1.5e-28 99.6 0.5 2.4e-20 72.6 0.5 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase DUF3293 PF11697.3 KEG07861.1 - 0.014 15.4 0.0 5.8 7.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3293) Galactosyl_T PF01762.16 KEG07863.1 - 2.4e-05 24.0 0.0 0.002 17.7 0.0 2.7 2 1 0 2 2 2 2 Galactosyltransferase Peptidase_C2 PF00648.16 KEG07864.1 - 2.3e-24 85.9 0.0 3.7e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 KEG07864.1 - 1.7e-11 44.0 0.4 5.7e-11 42.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1935) Ras PF00071.17 KEG07865.1 - 6.7e-17 61.3 0.0 7.9e-17 61.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.16 KEG07865.1 - 4.7e-05 22.6 0.0 6e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 KEG07865.1 - 0.011 16.2 0.0 0.016 15.6 0.0 1.3 1 0 0 1 1 1 0 Miro-like protein GTP_EFTU PF00009.22 KEG07865.1 - 0.02 14.3 0.0 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain zf-RanBP PF00641.13 KEG07866.1 - 7.8e-19 66.4 62.3 1e-06 27.7 1.3 7.4 8 0 0 8 8 8 5 Zn-finger in Ran binding protein and others FYVE PF01363.16 KEG07866.1 - 1.5e-18 66.4 12.5 1.5e-18 66.4 8.6 4.3 3 2 0 3 3 3 1 FYVE zinc finger DZR PF12773.2 KEG07866.1 - 0.016 15.0 57.9 0.19 11.5 7.2 5.7 1 1 5 6 6 6 0 Double zinc ribbon Ribosomal_S27e PF01667.12 KEG07867.1 - 4.2e-23 80.6 3.8 5.3e-23 80.3 2.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 KEG07867.1 - 0.0004 20.2 1.6 0.00048 19.9 1.1 1.2 1 0 0 1 1 1 1 IBR domain zinc_ribbon_4 PF13717.1 KEG07867.1 - 0.01 15.5 2.1 0.11 12.2 1.5 2.3 1 1 0 1 1 1 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 KEG07867.1 - 0.014 14.7 0.7 0.021 14.1 0.5 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding zinc_ribbon_5 PF13719.1 KEG07867.1 - 0.016 14.7 2.2 0.13 11.8 1.6 2.2 1 1 0 1 1 1 0 zinc-ribbon domain Elf1 PF05129.8 KEG07867.1 - 0.046 13.4 1.2 0.065 12.9 0.9 1.2 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.2 KEG07867.1 - 0.096 12.5 1.1 0.14 12.0 0.7 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain FYVE_2 PF02318.11 KEG07867.1 - 0.17 11.8 0.7 0.2 11.5 0.5 1.1 1 0 0 1 1 1 0 FYVE-type zinc finger Yippee-Mis18 PF03226.9 KEG07867.1 - 0.19 11.7 3.0 2.3 8.3 0.0 2.1 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Zn_Tnp_IS1 PF03811.8 KEG07867.1 - 0.48 9.9 6.4 1.6 8.3 4.4 1.9 1 1 0 1 1 1 0 InsA N-terminal domain zf-HIT PF04438.11 KEG07867.1 - 0.62 9.7 6.0 2.5 7.8 0.2 2.7 3 0 0 3 3 3 0 HIT zinc finger zf-LSD1 PF06943.7 KEG07867.1 - 0.8 9.3 6.7 6.6 6.4 0.1 3.1 3 0 0 3 3 3 0 LSD1 zinc finger OrfB_Zn_ribbon PF07282.6 KEG07867.1 - 1 9.0 4.2 0.83 9.3 2.1 1.5 1 1 0 1 1 1 0 Putative transposase DNA-binding domain zf-ISL3 PF14690.1 KEG07867.1 - 2.7 8.1 5.8 0.5 10.4 0.6 2.3 2 1 1 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Dpy-30 PF05186.8 KEG07868.1 - 1.3e-14 53.3 1.1 1.9e-14 52.8 0.8 1.3 1 0 0 1 1 1 1 Dpy-30 motif RIIa PF02197.12 KEG07868.1 - 0.011 15.1 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit Peptidase_M41 PF01434.13 KEG07869.1 - 2.3e-41 141.6 5.4 3.3e-41 141.1 3.7 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KEG07869.1 - 1.4e-39 135.2 0.0 3.2e-39 134.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEG07869.1 - 8.6e-05 22.5 0.6 0.00052 20.0 0.2 2.5 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KEG07869.1 - 0.00032 20.8 0.1 0.0037 17.3 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEG07869.1 - 0.00048 19.8 0.3 0.0019 17.9 0.2 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 KEG07869.1 - 0.00085 20.1 0.1 0.0029 18.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KEG07869.1 - 0.0011 18.7 0.1 0.0065 16.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KEG07869.1 - 0.0021 17.4 1.0 0.024 14.0 0.1 2.3 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.8 KEG07869.1 - 0.0024 16.6 0.0 0.0049 15.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_2 PF07724.9 KEG07869.1 - 0.0037 17.1 2.3 0.0067 16.3 0.2 2.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF2281 PF10047.4 KEG07869.1 - 0.0056 16.9 0.1 4.9 7.5 0.0 2.8 1 1 1 2 2 2 1 Protein of unknown function (DUF2281) AAA_14 PF13173.1 KEG07869.1 - 0.018 14.9 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Peptidase_M50B PF13398.1 KEG07869.1 - 0.019 14.3 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like RuvB_N PF05496.7 KEG07869.1 - 0.024 13.6 0.0 0.063 12.3 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 KEG07869.1 - 0.028 13.8 0.1 0.064 12.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.21 KEG07869.1 - 0.037 13.4 1.1 0.17 11.3 0.0 2.5 2 1 1 3 3 3 0 Sigma-54 interaction domain DUF2075 PF09848.4 KEG07869.1 - 0.049 12.6 0.0 0.082 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 KEG07869.1 - 0.058 12.4 0.7 0.2 10.7 0.0 2.1 2 0 0 2 2 2 0 KaiC NACHT PF05729.7 KEG07869.1 - 0.08 12.5 0.0 0.55 9.8 0.0 2.1 2 0 0 2 2 2 0 NACHT domain Cupin_8 PF13621.1 KEG07870.1 - 2.8e-12 46.7 0.0 3.1e-10 39.9 0.0 2.1 1 1 0 1 1 1 1 Cupin-like domain DUF2201_N PF13203.1 KEG07870.1 - 0.0073 15.5 0.0 0.0089 15.2 0.0 1.1 1 0 0 1 1 1 1 Putative metallopeptidase domain Cupin_8 PF13621.1 KEG07871.1 - 7.3e-50 169.7 0.0 8.2e-50 169.6 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KEG07871.1 - 0.12 11.5 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Cupin superfamily protein Utp12 PF04003.7 KEG07872.1 - 0.0013 18.6 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Aa_trans PF01490.13 KEG07874.1 - 3.1e-45 154.3 33.6 3.5e-45 154.2 23.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KEG07874.1 - 2.8e-11 42.8 11.2 2.8e-11 42.8 7.8 2.2 2 1 1 3 3 3 1 Tryptophan/tyrosine permease family AA_permease_2 PF13520.1 KEG07874.1 - 8.1e-06 24.6 24.1 8.1e-06 24.6 16.7 2.2 1 1 1 2 2 2 1 Amino acid permease Galactosyl_T PF01762.16 KEG07875.1 - 0.048 13.2 0.0 0.22 11.1 0.0 2.1 3 0 0 3 3 3 0 Galactosyltransferase DUF3173 PF11372.3 KEG07876.1 - 0.00026 20.5 0.1 0.47 10.0 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3173) DUF1751 PF08551.5 KEG07876.1 - 0.099 12.9 0.0 0.42 10.9 0.0 2.1 2 1 1 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) TisB_toxin PF13939.1 KEG07876.1 - 0.44 10.3 3.4 14 5.4 0.1 2.5 2 0 0 2 2 2 0 Toxin TisB, type I toxin-antitoxin system Galactosyl_T PF01762.16 KEG07877.1 - 1.7e-05 24.5 0.0 0.62 9.6 0.0 3.8 3 1 0 4 4 4 3 Galactosyltransferase DUF3333 PF11812.3 KEG07877.1 - 0.065 13.2 0.0 0.098 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3333) Ribosomal_L31e PF01198.14 KEG07879.1 - 9.3e-28 95.7 1.6 1.5e-27 95.0 1.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L31e Chordopox_G3 PF06129.7 KEG07879.1 - 0.047 13.8 0.0 0.062 13.4 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus G3 protein PBP_sp32 PF07222.7 KEG07880.1 - 0.21 10.7 3.6 0.098 11.8 1.2 1.3 1 1 0 1 1 1 0 Proacrosin binding protein sp32 Pex19 PF04614.7 KEG07881.1 - 1.6e-19 70.5 2.5 3.3e-18 66.2 0.0 2.6 1 1 1 2 2 2 2 Pex19 protein family AAA PF00004.24 KEG07882.1 - 2.7e-17 63.2 0.0 4.8e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KEG07882.1 - 2.9e-11 43.2 0.0 1.6e-10 40.9 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 KEG07882.1 - 5.6e-10 39.0 0.0 1.4e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 KEG07882.1 - 1.2e-09 37.4 0.0 2.6e-07 29.7 0.0 2.2 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KEG07882.1 - 4.3e-09 36.5 0.0 8.7e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KEG07882.1 - 5.4e-07 29.4 0.0 4.1e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KEG07882.1 - 6.2e-07 29.5 0.1 3.4e-06 27.1 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.1 KEG07882.1 - 8.3e-07 28.7 0.1 1.5e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KEG07882.1 - 1.6e-06 28.0 0.0 1.6e-05 24.7 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_11 PF13086.1 KEG07882.1 - 7.5e-06 25.6 1.5 0.0016 18.0 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 KEG07882.1 - 9.9e-06 25.2 2.7 6.6e-05 22.5 0.0 2.7 1 1 0 2 2 2 1 Part of AAA domain DUF815 PF05673.8 KEG07882.1 - 0.00018 20.5 0.0 0.0003 19.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 KEG07882.1 - 0.0006 19.7 0.1 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEG07882.1 - 0.0013 19.4 0.0 0.0053 17.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KEG07882.1 - 0.0014 18.1 0.5 0.53 9.6 0.0 2.2 1 1 1 2 2 2 2 AAA-like domain RuvB_N PF05496.7 KEG07882.1 - 0.0014 17.6 0.0 0.0027 16.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 KEG07882.1 - 0.0018 17.8 0.2 0.0038 16.8 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.1 KEG07882.1 - 0.0022 18.3 0.0 0.0032 17.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KEG07882.1 - 0.0047 16.1 0.0 0.013 14.6 0.0 1.7 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI DEAD PF00270.24 KEG07882.1 - 0.0048 16.3 0.3 0.024 14.1 0.0 2.0 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_3 PF07726.6 KEG07882.1 - 0.0057 16.2 0.0 0.03 13.9 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KEG07882.1 - 0.0068 15.8 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_29 PF13555.1 KEG07882.1 - 0.0087 15.5 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.1 KEG07882.1 - 0.0089 16.0 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 KEG07882.1 - 0.011 15.7 0.2 0.2 11.6 0.0 2.5 2 1 0 2 2 1 0 Sigma-54 interaction domain DUF2075 PF09848.4 KEG07882.1 - 0.014 14.3 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MobB PF03205.9 KEG07882.1 - 0.018 14.7 0.0 0.037 13.7 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 KEG07882.1 - 0.028 13.3 0.0 0.049 12.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.1 KEG07882.1 - 0.033 13.5 1.3 0.35 10.2 0.9 2.2 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 KEG07882.1 - 0.039 13.3 0.1 0.075 12.4 0.1 1.5 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain ArgK PF03308.11 KEG07882.1 - 0.042 12.6 0.1 7.6 5.2 0.0 2.2 1 1 1 2 2 2 0 ArgK protein Aminotran_5 PF00266.14 KEG07882.1 - 0.043 12.5 0.1 0.073 11.7 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V NB-ARC PF00931.17 KEG07882.1 - 0.054 12.3 0.0 2.6 6.8 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain ResIII PF04851.10 KEG07882.1 - 0.058 13.2 0.0 0.91 9.3 0.0 2.1 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 KEG07882.1 - 0.081 13.1 0.0 0.2 11.8 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 KEG07882.1 - 0.13 12.5 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 KEG07882.1 - 0.14 12.0 0.0 0.35 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_21 PF13304.1 KEG07882.1 - 0.21 11.5 0.0 0.31 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain SNAPc19 PF15497.1 KEG07883.1 - 0.0042 17.2 10.5 0.0042 17.2 7.3 3.5 4 1 0 4 4 4 1 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Baculo_PEP_C PF04513.7 KEG07883.1 - 1.6 8.5 7.3 2.9 7.7 0.3 3.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SNF2_N PF00176.18 KEG07885.1 - 1e-44 152.5 0.0 2.3e-44 151.4 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEG07885.1 - 2.4e-10 40.1 0.0 1.4e-09 37.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KEG07885.1 - 0.00015 20.6 0.0 0.00051 18.9 0.0 1.8 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 KEG07885.1 - 0.00051 19.9 0.1 0.005 16.7 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KEG07885.1 - 0.034 13.6 0.3 0.12 11.8 0.2 2.0 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_22 PF13401.1 KEG07885.1 - 0.051 13.7 0.0 0.25 11.4 0.0 2.2 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 KEG07885.1 - 0.087 11.7 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Orthopox_F8 PF05886.6 KEG07887.1 - 0.51 10.2 9.4 1.1 9.0 0.1 2.8 2 0 0 2 2 2 0 Orthopoxvirus F8 protein eIF-1a PF01176.14 KEG07888.1 - 9.8e-17 60.1 0.1 1.7e-16 59.3 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 UvrD_C_2 PF13538.1 KEG07889.1 - 0.052 13.6 0.0 0.091 12.9 0.0 1.4 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Ribosomal_L17 PF01196.14 KEG07891.1 - 2.9e-13 50.1 0.0 4.4e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L17 Peripla_BP_6 PF13458.1 KEG07896.1 - 1.5e-10 40.9 0.0 7.6e-05 22.2 0.0 2.3 2 0 0 2 2 2 2 Periplasmic binding protein Guanylate_cyc PF00211.15 KEG07896.1 - 2.2e-05 23.9 0.0 3.7e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF3481 PF11980.3 KEG07896.1 - 0.11 12.3 0.2 0.86 9.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3481) Ion_trans_2 PF07885.11 KEG07897.1 - 1.3e-11 44.0 2.3 1.3e-11 44.0 1.6 2.1 2 0 0 2 2 2 1 Ion channel Ldl_recept_a PF00057.13 KEG07898.1 - 0.092 12.6 1.3 0.22 11.4 0.9 1.7 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A DUF1930 PF09122.5 KEG07899.1 - 3.1e-25 87.7 0.1 5.6e-25 86.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1930) Rhodanese PF00581.15 KEG07899.1 - 1.1e-18 67.5 0.0 2.3e-10 40.8 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain DNA_ligase_OB_2 PF14743.1 KEG07904.1 - 1.5e-20 72.6 0.1 2.5e-20 71.9 0.1 1.4 1 0 0 1 1 1 1 DNA ligase OB-like domain DNA_ligase_A_M PF01068.16 KEG07904.1 - 1.3e-19 70.3 0.0 1.8e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DUF4379 PF14311.1 KEG07904.1 - 7e-13 48.1 2.5 1.4e-12 47.2 1.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4379) mRNA_cap_enzyme PF01331.14 KEG07904.1 - 0.089 12.4 0.0 1.2 8.7 0.0 2.1 1 1 0 1 1 1 0 mRNA capping enzyme, catalytic domain DNA_ligase_A_M PF01068.16 KEG07905.1 - 3.1e-20 72.3 0.0 8.6e-20 70.9 0.0 1.7 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_OB_2 PF14743.1 KEG07905.1 - 8e-20 70.2 0.0 1.4e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 DNA ligase OB-like domain DUF4379 PF14311.1 KEG07905.1 - 0.0034 17.1 4.1 0.01 15.5 2.8 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4379) FlhC PF05280.6 KEG07905.1 - 0.37 10.2 3.1 0.36 10.2 0.8 1.9 2 0 0 2 2 2 0 Flagellar transcriptional activator (FlhC) DivIC PF04977.10 KEG07907.1 - 0.0065 15.9 1.3 0.012 15.0 0.9 1.4 1 0 0 1 1 1 1 Septum formation initiator ADIP PF11559.3 KEG07907.1 - 0.013 15.4 3.0 0.018 14.9 2.1 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Myosin_tail_1 PF01576.14 KEG07907.1 - 0.023 12.4 1.0 0.028 12.1 0.7 1.0 1 0 0 1 1 1 0 Myosin tail Chibby PF14645.1 KEG07907.1 - 0.04 13.8 0.6 0.059 13.2 0.4 1.4 1 0 0 1 1 1 0 Chibby family V_ATPase_I PF01496.14 KEG07907.1 - 0.053 11.3 0.1 0.047 11.5 0.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 KEG07907.1 - 0.068 13.5 0.8 0.12 12.7 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) HOOK PF05622.7 KEG07907.1 - 0.11 10.2 2.4 0.15 9.8 1.7 1.1 1 0 0 1 1 1 0 HOOK protein Ax_dynein_light PF10211.4 KEG07907.1 - 0.15 11.9 3.0 0.19 11.5 1.8 1.4 1 1 0 1 1 1 0 Axonemal dynein light chain TFCD_C PF12612.3 KEG07910.1 - 6.5e-39 133.3 0.1 2.2e-38 131.6 0.1 1.9 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal PI3_PI4_kinase PF00454.22 KEG07911.1 - 1.3e-45 155.7 0.0 5.6e-43 147.0 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 KEG07911.1 - 1.9e-39 134.7 0.7 3.3e-39 133.9 0.5 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.19 KEG07911.1 - 6.6e-10 38.9 0.0 4.2e-09 36.3 0.0 2.1 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 APO_RNA-bind PF05634.6 KEG07911.1 - 0.035 13.3 0.0 0.11 11.6 0.0 1.7 2 0 0 2 2 2 0 APO RNA-binding DUF4135 PF13575.1 KEG07911.1 - 0.15 11.0 0.0 0.27 10.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) PCIF1_WW PF12237.3 KEG07912.1 - 5.9e-09 35.4 0.2 2.3e-08 33.5 0.1 1.9 1 1 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain Lysine_decarbox PF03641.9 KEG07914.1 - 6.2e-08 32.5 0.0 7.3e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase Thioredoxin_7 PF13899.1 KEG07915.1 - 3.9e-07 30.0 0.1 1e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.15 KEG07915.1 - 1.7e-06 27.9 0.0 3.2e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 UBX domain Atg14 PF10186.4 KEG07915.1 - 7.4 5.4 13.5 12 4.7 9.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Trypsin_2 PF13365.1 KEG07916.1 - 0.00038 20.4 0.0 0.00068 19.6 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S68 PF10461.4 KEG07918.1 - 0.32 10.7 1.9 1.7 8.4 0.4 2.3 2 0 0 2 2 2 0 Peptidase S68 Thioredoxin PF00085.15 KEG07921.1 - 2.9e-10 39.7 0.2 4e-10 39.3 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KEG07921.1 - 0.0002 21.3 0.5 0.00052 20.0 0.1 1.8 2 0 0 2 2 2 1 Thioredoxin-like M16C_assoc PF08367.6 KEG07921.1 - 0.0081 15.0 0.1 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16C associated AhpC-TSA PF00578.16 KEG07921.1 - 0.017 14.8 0.1 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family DIM1 PF02966.11 KEG07921.1 - 0.064 12.7 0.0 0.074 12.5 0.0 1.2 1 0 0 1 1 1 0 Mitosis protein DIM1 Thioredoxin_7 PF13899.1 KEG07921.1 - 0.083 12.9 0.1 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like MFS_1 PF07690.11 KEG07923.1 - 2.1e-18 66.1 49.0 5.6e-12 45.0 24.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.11 KEG07923.1 - 5.2e-11 41.9 24.0 7.1e-11 41.4 16.7 1.1 1 0 0 1 1 1 1 Nucleoside H+ symporter MFS_1_like PF12832.2 KEG07923.1 - 3e-05 23.7 3.3 3e-05 23.7 2.3 2.5 3 0 0 3 3 3 1 MFS_1 like family LacY_symp PF01306.14 KEG07923.1 - 0.00018 20.1 23.0 0.00035 19.2 16.0 1.3 1 1 0 1 1 1 1 LacY proton/sugar symporter MFS_2 PF13347.1 KEG07923.1 - 0.26 9.6 33.2 0.035 12.5 18.9 2.1 2 0 0 2 2 2 0 MFS/sugar transport protein Solute_trans_a PF03619.11 KEG07924.1 - 3.3e-89 298.8 12.5 4.2e-89 298.5 8.7 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Prok-RING_2 PF14445.1 KEG07924.1 - 0.013 15.4 0.2 0.026 14.4 0.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 Skp1 PF01466.14 KEG07925.1 - 2.2e-32 110.8 1.9 3.5e-32 110.2 1.3 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 KEG07925.1 - 8.4e-15 54.6 0.1 2.8e-14 52.9 0.0 1.9 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain PPR_2 PF13041.1 KEG07927.1 - 4e-14 52.3 0.1 8.1e-06 25.7 0.0 4.5 4 1 1 5 5 5 4 PPR repeat family PPR_3 PF13812.1 KEG07927.1 - 6.3e-08 32.3 15.2 2.2 8.7 0.1 8.6 9 0 0 9 9 9 4 Pentatricopeptide repeat domain PPR PF01535.15 KEG07927.1 - 2e-05 24.2 3.2 0.23 11.5 0.0 6.1 6 1 0 6 6 6 1 PPR repeat PPR_1 PF12854.2 KEG07927.1 - 0.00018 20.9 2.4 1 8.8 0.0 5.0 4 1 0 4 4 4 1 PPR repeat EH_Signature PF15611.1 KEG07927.1 - 0.017 14.1 0.2 0.24 10.3 0.0 2.4 1 1 1 2 2 2 0 EH_Signature domain Pkinase PF00069.20 KEG07928.1 - 3.6e-59 200.0 0.0 6.5e-59 199.1 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG07928.1 - 4.4e-42 143.9 0.0 2.6e-41 141.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_A32 PF04665.7 KEG07928.1 - 0.036 13.3 0.0 0.062 12.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein Kdo PF06293.9 KEG07928.1 - 0.079 12.0 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family C2 PF00168.25 KEG07930.1 - 0.07 12.9 0.1 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 C2 domain Filament PF00038.16 KEG07932.1 - 0.0049 16.3 17.8 0.0049 16.3 12.3 5.3 3 1 3 6 6 6 3 Intermediate filament protein TPR_MLP1_2 PF07926.7 KEG07932.1 - 0.0054 16.4 6.5 0.0054 16.4 4.5 6.0 3 1 3 6 6 6 2 TPR/MLP1/MLP2-like protein GAS PF13851.1 KEG07932.1 - 0.045 12.9 69.3 0.13 11.3 11.0 4.7 4 1 1 5 5 5 0 Growth-arrest specific micro-tubule binding Pro_isomerase PF00160.16 KEG07933.1 - 2.3e-27 96.1 0.0 2.7e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ATP-synt_C PF00137.16 KEG07934.1 - 1.3e-26 92.2 31.4 3.9e-17 61.9 7.2 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF2592 PF10766.4 KEG07934.1 - 0.86 8.9 12.8 0.073 12.4 4.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2592) GerA PF03323.8 KEG07934.1 - 3.1 5.8 7.9 2 6.4 0.9 2.1 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein DUF4064 PF13273.1 KEG07934.1 - 4 7.6 14.6 0.44 10.6 3.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Abi PF02517.11 KEG07934.1 - 4.2 7.5 5.8 19 5.4 3.5 2.3 1 1 0 1 1 1 0 CAAX protease self-immunity Abhydrolase_6 PF12697.2 KEG07935.1 - 2.1e-28 99.7 0.6 2.6e-28 99.4 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEG07935.1 - 5.2e-12 45.7 0.1 8.7e-12 45.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEG07935.1 - 1.6e-10 40.9 0.0 2.2e-09 37.2 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KEG07935.1 - 0.00036 20.3 0.1 0.0009 19.0 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 KEG07935.1 - 0.014 15.6 0.7 0.069 13.3 0.2 2.3 2 1 0 2 2 2 0 Thioesterase domain PGAP1 PF07819.8 KEG07935.1 - 0.014 14.9 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_3 PF07859.8 KEG07935.1 - 0.015 14.8 0.0 0.22 11.0 0.0 2.1 1 1 0 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 KEG07935.1 - 0.051 13.1 0.0 1.8 8.1 0.0 2.4 2 0 0 2 2 2 0 Lipase (class 3) DUF2305 PF10230.4 KEG07935.1 - 0.055 12.8 0.0 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Ser_hydrolase PF06821.8 KEG07935.1 - 0.062 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase ATPase_gene1 PF09527.5 KEG07935.1 - 0.11 12.3 0.8 0.25 11.1 0.6 1.6 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit (ATPase_gene1) LRR_6 PF13516.1 KEG07936.1 - 6e-14 50.5 20.4 0.015 15.3 0.0 9.7 9 1 0 9 9 9 4 Leucine Rich repeat LRR_8 PF13855.1 KEG07936.1 - 1.6e-08 34.1 2.0 0.049 13.3 0.0 5.3 3 2 2 5 5 5 2 Leucine rich repeat LRR_4 PF12799.2 KEG07936.1 - 8.5e-06 25.2 11.1 1.8 8.2 0.0 6.3 4 3 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEG07936.1 - 0.0012 18.6 4.8 19 5.7 0.0 6.9 9 0 0 9 9 9 1 Leucine Rich Repeat LRR_7 PF13504.1 KEG07936.1 - 0.032 14.3 12.6 17 6.1 0.0 7.1 8 0 0 8 8 8 0 Leucine rich repeat cNMP_binding PF00027.24 KEG07937.1 - 2.4e-08 33.6 0.5 6.2e-06 25.9 0.1 2.9 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain Atg14 PF10186.4 KEG07938.1 - 0.01 14.8 2.4 0.012 14.5 1.7 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 KEG07938.1 - 0.01 15.4 0.7 0.012 15.2 0.5 1.1 1 0 0 1 1 1 0 IncA protein RskA PF10099.4 KEG07938.1 - 0.017 14.9 2.8 0.02 14.6 2.0 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF2066 PF09839.4 KEG07938.1 - 0.022 13.8 0.6 0.032 13.3 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2066) Nup54 PF13874.1 KEG07938.1 - 2.7 7.6 8.2 4.2 7.0 5.7 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 WXG100 PF06013.7 KEG07938.1 - 7 6.7 7.7 5.2 7.1 0.9 3.3 2 1 1 3 3 3 0 Proteins of 100 residues with WXG FliJ PF02050.11 KEG07940.1 - 0.0049 16.9 10.3 0.0049 16.9 7.2 2.2 1 1 0 2 2 2 1 Flagellar FliJ protein Ribosomal_S20p PF01649.13 KEG07940.1 - 1 9.7 10.3 6.2 7.2 0.5 2.3 2 0 0 2 2 2 0 Ribosomal protein S20 Mucin PF01456.12 KEG07940.1 - 3 7.6 10.8 16 5.2 7.4 2.2 1 1 0 1 1 1 0 Mucin-like glycoprotein DUF3461 PF11944.3 KEG07940.1 - 5.6 6.8 8.6 14 5.5 0.9 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3461) DUF2203 PF09969.4 KEG07940.1 - 5.6 7.2 8.7 3.8 7.7 0.4 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF972 PF06156.8 KEG07940.1 - 7.2 7.0 11.8 1.3 9.3 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) RR_TM4-6 PF06459.7 KEG07940.1 - 7.8 6.2 13.4 11 5.8 9.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ada_Zn_binding PF02805.11 KEG07941.1 - 0.038 13.5 0.2 0.13 11.8 0.2 1.9 1 0 0 1 1 1 0 Metal binding domain of Ada TMPIT PF07851.8 KEG07941.1 - 0.86 8.6 9.4 4.7 6.1 0.4 2.2 1 1 1 2 2 2 0 TMPIT-like protein DUF2201_N PF13203.1 KEG07942.1 - 2.8 7.0 6.6 4 6.5 4.6 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Mucin PF01456.12 KEG07943.1 - 0.0063 16.2 11.6 0.0063 16.2 8.0 3.7 1 1 2 3 3 3 1 Mucin-like glycoprotein DUF922 PF06037.6 KEG07943.1 - 0.068 12.4 1.5 7.9 5.7 0.1 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF922) IncA PF04156.9 KEG07943.1 - 0.1 12.2 6.3 0.19 11.2 0.1 2.7 1 1 0 2 2 2 0 IncA protein HisKA_2 PF07568.7 KEG07943.1 - 0.3 10.9 1.5 13 5.7 0.0 2.7 1 1 0 2 2 2 0 Histidine kinase DUF1664 PF07889.7 KEG07943.1 - 0.81 9.4 13.2 1.4 8.7 0.9 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) ATP-synt_D PF01813.12 KEG07943.1 - 2.8 7.4 19.3 0.22 11.0 5.5 2.5 3 0 0 3 3 3 0 ATP synthase subunit D BLOC1_2 PF10046.4 KEG07943.1 - 4.3 7.5 11.0 0.28 11.3 0.7 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 COG2 PF06148.6 KEG07943.1 - 5.7 6.8 12.4 8 6.3 1.2 3.7 1 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 NPV_P10 PF05531.7 KEG07943.1 - 6.2 7.1 10.5 0.89 9.8 1.1 2.9 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.5 KEG07943.1 - 6.4 6.8 15.0 9.8 6.2 1.3 3.6 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family Peptidase_S9_N PF02897.10 KEG07945.1 - 5.9e-40 137.1 0.2 4.4e-31 107.8 0.2 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 KEG07946.1 - 2.1e-47 161.0 0.0 2.6e-47 160.7 0.0 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 KEG07946.1 - 0.00037 20.0 0.1 0.0011 18.4 0.0 1.7 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.8 KEG07946.1 - 0.0014 18.2 0.4 0.0029 17.2 0.3 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEG07946.1 - 0.0027 17.4 0.3 0.0049 16.6 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEG07946.1 - 0.043 13.6 2.7 0.053 13.3 1.9 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family zf-C3HC4_3 PF13920.1 KEG07948.1 - 3.4e-07 29.8 2.5 5.7e-07 29.1 1.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEG07948.1 - 2.6e-06 27.0 4.2 4.2e-06 26.3 2.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KEG07948.1 - 3e-06 27.1 7.9 4.8e-06 26.4 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KEG07948.1 - 5.3e-06 26.2 8.7 8.7e-06 25.5 6.1 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KEG07948.1 - 1e-05 25.0 3.6 1.8e-05 24.3 2.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEG07948.1 - 0.00036 20.2 7.8 0.00061 19.5 5.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 KEG07948.1 - 0.00093 18.8 2.6 0.0021 17.7 1.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 KEG07948.1 - 0.02 14.4 1.5 0.039 13.5 1.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 KEG07948.1 - 0.045 13.5 3.1 0.11 12.3 2.2 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein MIP-T3 PF10243.4 KEG07948.1 - 0.17 10.3 32.2 0.24 9.8 22.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 zf-rbx1 PF12678.2 KEG07948.1 - 0.18 11.8 1.8 0.35 11.0 1.2 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger PAT1 PF09770.4 KEG07948.1 - 2.2 6.4 45.6 3 5.9 31.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.11 KEG07948.1 - 2.8 7.7 9.4 4.6 7.0 6.5 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Period_C PF12114.3 KEG07950.1 - 1.4 8.5 7.9 2.5 7.6 5.5 1.4 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Metallophos PF00149.23 KEG07954.1 - 2.7e-11 43.2 0.8 7.5e-11 41.7 0.0 2.0 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KEG07954.1 - 2.4e-07 30.7 0.0 4.9e-07 29.7 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Cupin_8 PF13621.1 KEG07956.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Cupin-like domain Aldose_epim PF01263.15 KEG07957.1 - 6.1e-56 189.7 0.0 7.6e-56 189.4 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Ribosomal_L2 PF00181.18 KEG07960.1 - 5.8e-12 45.4 0.0 9.5e-12 44.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain TPR_11 PF13414.1 KEG07961.1 - 1.8e-21 75.5 16.0 3.7e-12 45.7 1.6 4.8 2 2 2 5 5 5 4 TPR repeat TPR_16 PF13432.1 KEG07961.1 - 1.9e-17 63.4 19.5 8.4e-07 29.5 0.3 5.3 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 KEG07961.1 - 4e-16 57.8 11.3 8.8e-07 28.2 0.2 5.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEG07961.1 - 6e-16 57.0 12.7 4.3e-05 23.1 0.2 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 KEG07961.1 - 1e-15 56.5 16.6 0.00017 21.4 0.8 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 KEG07961.1 - 8.6e-11 41.6 5.5 5.3e-06 26.2 0.7 3.5 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 KEG07961.1 - 8.3e-09 35.3 32.8 0.0033 17.9 0.0 8.8 6 2 4 10 10 9 5 Tetratricopeptide repeat TPR_8 PF13181.1 KEG07961.1 - 1.1e-06 27.9 2.1 0.045 13.5 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEG07961.1 - 2e-06 28.0 19.3 0.00043 20.5 0.5 5.4 3 2 3 6 6 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 KEG07961.1 - 7.9e-05 22.1 0.6 0.8 9.6 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 KEG07961.1 - 0.0064 16.8 9.9 0.44 11.1 0.9 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KEG07961.1 - 0.029 14.2 2.2 48 3.9 0.0 4.3 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat KNOX1 PF03790.8 KEG07961.1 - 0.051 12.9 0.1 1.6 8.1 0.0 2.7 2 0 0 2 2 2 0 KNOX1 domain TPR_9 PF13371.1 KEG07961.1 - 0.13 12.1 20.4 0.22 11.3 0.0 5.1 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_20 PF14561.1 KEG07961.1 - 0.61 10.2 21.1 2.1 8.5 0.5 5.1 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 KEG07961.1 - 1 9.4 12.4 5.9 6.9 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat tRNA-synt_2b PF00587.20 KEG07962.1 - 2.7e-42 144.2 0.2 7.8e-42 142.7 0.4 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KEG07962.1 - 1.4e-16 60.2 0.3 3.3e-16 59.0 0.1 1.8 2 0 0 2 2 2 1 Anticodon binding domain TGS PF02824.16 KEG07962.1 - 4.2e-14 52.1 0.0 8.8e-13 47.8 0.0 2.5 2 0 0 2 2 2 1 TGS domain tRNA_SAD PF07973.9 KEG07962.1 - 5.3e-10 39.0 0.0 8.8e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain GcrA PF07750.6 KEG07963.1 - 0.28 11.3 4.2 0.28 11.3 2.9 1.0 1 0 0 1 1 1 0 GcrA cell cycle regulator DUF4457 PF14652.1 KEG07964.1 - 6.3e-31 107.5 0.0 7.5e-10 38.2 0.0 5.3 4 2 0 4 4 4 4 Domain of unknown function (DUF4457) TRAM_LAG1_CLN8 PF03798.11 KEG07965.1 - 3.6e-22 78.8 15.4 3.6e-22 78.8 10.7 1.6 2 0 0 2 2 2 1 TLC domain HEAT_2 PF13646.1 KEG07966.1 - 6.6e-07 29.5 0.1 7.3e-07 29.3 0.1 1.2 1 1 0 1 1 1 1 HEAT repeats HEAT_PBS PF03130.11 KEG07966.1 - 0.00099 19.3 0.5 0.0034 17.7 0.0 2.0 2 1 0 2 2 2 1 PBS lyase HEAT-like repeat HEAT PF02985.17 KEG07966.1 - 0.0036 17.2 1.8 1.1 9.5 0.0 2.6 3 0 0 3 3 3 2 HEAT repeat Peptidase_M56 PF05569.6 KEG07967.1 - 0.0041 16.1 0.0 0.0048 15.9 0.0 1.0 1 0 0 1 1 1 1 BlaR1 peptidase M56 ERGIC_N PF13850.1 KEG07967.1 - 0.08 12.9 0.1 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) zf-LITAF-like PF10601.4 KEG07967.1 - 0.11 12.3 3.7 0.2 11.5 0.3 2.1 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain PUF PF00806.14 KEG07968.1 - 7.5e-53 173.1 3.8 9.2e-07 28.0 0.0 9.2 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat Ax_dynein_light PF10211.4 KEG07969.1 - 2.2e-54 184.1 8.7 2.6e-54 183.9 6.0 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain APC8 PF04049.8 KEG07969.1 - 0.04 13.6 0.2 0.059 13.1 0.2 1.3 1 0 0 1 1 1 0 Anaphase promoting complex subunit 8 / Cdc23 PPR_2 PF13041.1 KEG07971.1 - 1.2e-05 25.1 0.0 0.0023 17.8 0.0 2.8 2 0 0 2 2 2 2 PPR repeat family PPR PF01535.15 KEG07971.1 - 0.0012 18.6 0.0 27 5.0 0.0 3.8 4 0 0 4 4 4 3 PPR repeat PPR_3 PF13812.1 KEG07971.1 - 0.054 13.7 0.9 2.1 8.8 0.0 3.6 5 0 0 5 5 5 0 Pentatricopeptide repeat domain AAA PF00004.24 KEG07974.1 - 7.7e-43 145.8 0.0 1.6e-42 144.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEG07974.1 - 5.9e-07 29.6 0.1 0.00021 21.4 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KEG07974.1 - 1.1e-06 28.3 0.2 4e-05 23.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KEG07974.1 - 6.8e-06 26.1 0.0 1.4e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KEG07974.1 - 1.9e-05 24.7 0.0 3.2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KEG07974.1 - 7.8e-05 23.4 0.5 0.00018 22.3 0.1 2.0 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 KEG07974.1 - 0.00028 20.0 0.0 0.0005 19.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 KEG07974.1 - 0.00054 18.9 0.0 0.00097 18.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 KEG07974.1 - 0.0006 19.5 0.1 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 KEG07974.1 - 0.0011 18.9 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KEG07974.1 - 0.0014 18.4 0.0 0.003 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KEG07974.1 - 0.002 17.2 0.0 0.0035 16.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 KEG07974.1 - 0.0025 17.6 0.0 0.0051 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KEG07974.1 - 0.0027 17.1 0.0 0.0042 16.5 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Arch_ATPase PF01637.13 KEG07974.1 - 0.0034 17.1 0.2 0.23 11.1 0.0 2.6 2 1 1 3 3 3 1 Archaeal ATPase RNA_helicase PF00910.17 KEG07974.1 - 0.0051 16.9 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 KEG07974.1 - 0.0067 16.7 0.0 0.02 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KEG07974.1 - 0.0082 15.3 0.0 0.018 14.1 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 KEG07974.1 - 0.0083 15.7 0.1 0.017 14.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KEG07974.1 - 0.0085 14.8 0.0 0.017 13.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_3 PF07726.6 KEG07974.1 - 0.011 15.2 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 KEG07974.1 - 0.018 14.7 0.1 0.036 13.7 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_25 PF13481.1 KEG07974.1 - 0.026 13.9 1.2 0.14 11.5 0.1 2.2 1 1 0 2 2 2 0 AAA domain Histone PF00125.19 KEG07974.1 - 0.043 13.9 0.1 0.19 11.8 0.0 2.2 2 0 0 2 2 1 0 Core histone H2A/H2B/H3/H4 Sigma54_activat PF00158.21 KEG07974.1 - 0.044 13.2 0.0 0.16 11.4 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.1 KEG07974.1 - 0.047 13.2 0.0 0.22 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 KEG07974.1 - 0.067 12.4 0.3 0.16 11.1 0.1 1.7 1 1 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 KEG07974.1 - 0.071 11.9 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 KEG07974.1 - 0.093 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activ_2 PF14532.1 KEG07974.1 - 0.17 11.8 0.0 0.47 10.5 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Rer1 PF03248.8 KEG07975.1 - 1.5e-60 203.8 5.2 1.7e-60 203.5 3.6 1.0 1 0 0 1 1 1 1 Rer1 family DUF2628 PF10947.3 KEG07975.1 - 0.03 14.1 2.7 0.28 10.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) UPF0066 PF01980.11 KEG07976.1 - 2.7e-30 104.7 0.0 4.5e-30 104.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family UPF0066 PWWP PF00855.12 KEG07976.1 - 0.00079 19.5 0.6 0.002 18.2 0.4 1.8 1 1 0 1 1 1 1 PWWP domain Acetyltransf_3 PF13302.1 KEG07977.1 - 1.6e-20 73.7 0.6 1.6e-19 70.4 0.4 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KEG07977.1 - 6e-08 32.7 0.1 4.3e-05 23.4 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KEG07977.1 - 1.2e-06 28.4 0.0 1.9e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KEG07977.1 - 1.4e-05 25.0 0.0 2.5e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEG07977.1 - 0.0067 16.1 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein UQ_con PF00179.21 KEG07978.1 - 1.5e-43 147.6 0.0 2.8e-43 146.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KEG07978.1 - 0.0022 17.7 0.3 0.0068 16.1 0.0 1.8 2 0 0 2 2 2 1 Prokaryotic E2 family B UFC1 PF08694.6 KEG07978.1 - 0.083 12.3 0.0 0.14 11.6 0.0 1.3 1 1 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Pex14_N PF04695.8 KEG07978.1 - 0.094 12.7 4.0 0.15 12.1 2.8 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAM176 PF14851.1 KEG07978.1 - 0.39 10.3 2.2 0.65 9.6 1.5 1.3 1 0 0 1 1 1 0 FAM176 family Hid1 PF12722.2 KEG07978.1 - 6.3 4.3 6.2 10 3.6 4.3 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MT PF12777.2 KEG07979.1 - 3e-05 22.9 0.5 3e-05 22.9 0.4 1.5 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor SmpA_OmlA PF04355.8 KEG07979.1 - 0.04 13.5 0.1 22 4.7 0.0 4.2 4 1 0 4 4 4 0 SmpA / OmlA family Mnd1 PF03962.10 KEG07979.1 - 1.9 8.0 24.3 0.021 14.5 4.8 3.3 3 0 0 3 3 3 0 Mnd1 family MmlI PF09448.5 KEG07980.1 - 0.023 14.4 0.3 0.85 9.3 0.0 2.9 2 2 1 3 3 3 0 Methylmuconolactone methyl-isomerase SmpA_OmlA PF04355.8 KEG07980.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 SmpA / OmlA family DUF4379 PF14311.1 KEG07981.1 - 5.5e-21 74.1 5.1 2.3e-15 56.1 0.8 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4379) Zn-ribbon_8 PF09723.5 KEG07981.1 - 0.043 13.7 0.8 0.11 12.4 0.6 1.7 1 0 0 1 1 1 0 Zinc ribbon domain HypA PF01155.14 KEG07981.1 - 0.22 11.1 3.2 1.3 8.7 0.2 2.6 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Pkinase PF00069.20 KEG07982.1 - 1.4e-57 194.8 0.0 2.2e-57 194.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG07982.1 - 8.4e-30 103.6 0.0 1.3e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG07982.1 - 1e-10 41.0 0.0 1.6e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEG07982.1 - 9.3e-05 22.2 6.2 0.0017 18.1 0.6 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family MMR_HSR1 PF01926.18 KEG07984.1 - 2.2e-16 59.8 0.0 4.9e-14 52.2 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 KEG07984.1 - 1.5e-06 27.5 0.0 1.1e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.11 KEG07984.1 - 0.00012 21.2 0.0 0.00034 19.7 0.0 1.8 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 KEG07984.1 - 0.09 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Miro PF08477.8 KEG07984.1 - 0.12 12.9 0.0 0.37 11.3 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein Fip1 PF05182.8 KEG07985.1 - 1.3e-20 72.3 0.9 2.3e-20 71.5 0.6 1.5 1 0 0 1 1 1 1 Fip1 motif zf-CCCH PF00642.19 KEG07985.1 - 5e-05 22.8 3.1 0.00012 21.6 2.2 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Neur_chan_memb PF02932.11 KEG07985.1 - 0.05 13.4 2.7 0.078 12.8 1.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Med15 PF09606.5 KEG07985.1 - 6.4 4.8 27.6 3.4 5.7 5.5 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal 2-oxoacid_dh PF00198.18 KEG07986.1 - 1.1e-73 247.3 0.0 1.5e-73 246.9 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KEG07986.1 - 3.9e-17 61.6 0.4 9.7e-17 60.3 0.3 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KEG07986.1 - 3.4e-14 52.1 0.0 8.2e-14 50.9 0.0 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 KEG07986.1 - 0.065 12.9 1.0 0.79 9.4 0.3 2.4 1 1 1 2 2 2 0 Biotin-lipoyl like MRP-L20 PF12824.2 KEG07986.1 - 0.097 12.6 0.3 0.15 11.9 0.2 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 Mucin PF01456.12 KEG07987.1 - 0.0024 17.6 5.3 0.0024 17.6 3.7 2.3 2 0 0 2 2 2 1 Mucin-like glycoprotein MOZ_SAS PF01853.13 KEG07989.1 - 1.3e-39 135.3 0.2 2.1e-38 131.4 0.0 2.3 2 1 0 2 2 2 1 MOZ/SAS family HATPase_c PF02518.21 KEG07990.1 - 3.8e-11 42.6 0.0 5.6e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KEG07990.1 - 0.0012 18.4 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_gyraseB PF00204.20 KEG07991.1 - 7.8e-11 41.4 0.0 1.1e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 DNA gyrase B Phos_pyr_kin PF08543.7 KEG07991.1 - 0.089 11.9 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase DNA_topoisoIV PF00521.15 KEG07992.1 - 1.3e-127 426.2 0.0 1.9e-127 425.6 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A Toprim PF01751.17 KEG07992.1 - 0.00051 19.9 0.0 0.0016 18.3 0.0 1.9 1 0 0 1 1 1 1 Toprim domain Pyr_excise PF03013.9 KEG07992.1 - 2.8 7.7 8.1 4.5 7.0 0.0 3.6 4 0 0 4 4 4 0 Pyrimidine dimer DNA glycosylase zf-CCCH PF00642.19 KEG07993.1 - 0.0041 16.7 11.7 0.54 10.0 4.2 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH PF00642.19 KEG07994.1 - 0.00022 20.8 9.8 0.032 13.9 0.4 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KEG07994.1 - 0.2 11.6 0.1 0.2 11.6 0.1 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type HemX PF04375.9 KEG07996.1 - 0.11 11.0 0.1 0.21 10.1 0.0 1.4 1 0 0 1 1 1 0 HemX Exo_endo_phos_2 PF14529.1 KEG07997.1 - 9.1e-06 25.2 0.0 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 KEG07997.1 - 0.00074 19.5 0.1 0.0077 16.1 0.0 1.9 1 1 1 2 2 2 1 Endonuclease/Exonuclease/phosphatase family zf-DHHC PF01529.15 KEG08001.1 - 1.5e-15 57.0 2.2 1.5e-15 57.0 1.5 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase 2OG-FeII_Oxy_2 PF13532.1 KEG08002.1 - 1.9e-49 168.1 0.0 3.1e-49 167.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Coatomer_WDAD PF04053.9 KEG08003.1 - 1.9e-97 326.8 0.0 2.9e-97 326.2 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 KEG08003.1 - 2.3e-79 266.9 0.0 7.5e-79 265.2 0.0 1.7 2 0 0 2 2 2 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 KEG08003.1 - 2.5e-51 169.8 15.3 3.2e-10 39.4 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KEG08003.1 - 0.16 10.6 0.0 17 3.9 0.0 2.8 2 1 1 3 3 3 0 Nup133 N terminal like Nup160 PF11715.3 KEG08003.1 - 0.44 8.6 4.6 3.7 5.5 0.1 3.3 2 2 0 3 3 3 0 Nucleoporin Nup120/160 ESSS PF10183.4 KEG08004.1 - 2.5e-14 53.5 4.8 2.8e-14 53.3 3.3 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF1470 PF07336.6 KEG08006.1 - 0.032 14.5 3.0 0.032 14.5 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1470) DUF883 PF05957.8 KEG08006.1 - 0.73 10.2 6.4 0.13 12.7 0.8 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) CDK2AP PF09806.4 KEG08006.1 - 1.4 9.0 8.8 0.21 11.7 2.2 2.0 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein FAD_binding_2 PF00890.19 KEG08008.1 - 3.8e-81 273.0 1.1 3.8e-81 273.0 0.8 1.6 2 0 0 2 2 2 1 FAD binding domain Cyt-b5 PF00173.23 KEG08008.1 - 9.7e-22 76.5 0.0 3.9e-21 74.6 0.0 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FAD_oxidored PF12831.2 KEG08008.1 - 2.6e-11 43.2 2.0 1.6e-10 40.6 1.4 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 KEG08008.1 - 3.5e-11 42.6 3.7 5.9e-08 31.9 0.5 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KEG08008.1 - 6.2e-08 32.7 0.3 0.0003 20.7 0.2 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEG08008.1 - 7.3e-06 25.9 1.7 7.3e-06 25.9 1.1 2.6 3 1 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KEG08008.1 - 1.1e-05 25.6 0.0 9.5e-05 22.5 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEG08008.1 - 0.00043 18.8 7.3 0.00046 18.7 0.4 3.0 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.17 KEG08008.1 - 0.0013 17.6 5.3 0.0014 17.5 0.6 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 KEG08008.1 - 0.019 14.0 1.6 0.038 13.0 1.1 1.4 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 KEG08008.1 - 0.2 10.7 5.5 3.9 6.4 0.0 2.4 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.7 KEG08008.1 - 2.1 7.1 5.1 0.29 10.0 0.3 1.9 3 0 0 3 3 3 0 Lycopene cyclase protein NMD3 PF04981.8 KEG08009.1 - 4.4e-74 248.5 4.6 6.6e-74 247.9 3.2 1.3 1 0 0 1 1 1 1 NMD3 family FTR1 PF03239.9 KEG08010.1 - 0.019 13.9 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Iron permease FTR1 family GDH_N PF12466.3 KEG08010.1 - 0.09 12.7 1.8 0.26 11.2 0.1 2.8 3 0 0 3 3 3 0 Glutamate dehydrogenase N terminal TM140 PF14985.1 KEG08015.1 - 0.092 12.4 0.5 0.14 11.8 0.0 1.6 2 1 1 3 3 3 0 TM140 protein family Phage_holin_5 PF06946.6 KEG08018.1 - 0.014 15.4 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 Phage holin DUF4657 PF15552.1 KEG08020.1 - 0.027 13.7 1.5 0.035 13.4 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4657) Bromodomain PF00439.20 KEG08020.1 - 0.029 14.2 0.0 0.087 12.7 0.0 1.8 1 1 0 1 1 1 0 Bromodomain GHMP_kinases_C PF08544.8 KEG08020.1 - 3.9 7.7 6.5 7.2 6.8 3.7 2.0 2 0 0 2 2 2 0 GHMP kinases C terminal UCR_hinge PF02320.11 KEG08023.1 - 0.002 18.0 1.0 0.081 12.8 0.0 2.7 2 1 0 2 2 2 1 Ubiquinol-cytochrome C reductase hinge protein DNA_repr_REX1B PF14966.1 KEG08023.1 - 0.023 15.0 2.0 0.041 14.2 0.5 2.1 2 0 0 2 2 2 0 DNA repair REX1-B Apolipoprotein PF01442.13 KEG08023.1 - 0.038 13.5 12.9 1.2 8.6 8.2 2.9 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain ABA_WDS PF02496.11 KEG08023.1 - 0.52 10.5 6.9 0.58 10.3 0.3 3.0 3 0 0 3 3 3 0 ABA/WDS induced protein MTBP_C PF14920.1 KEG08024.1 - 1.6 8.1 9.2 4.3 6.7 0.1 2.3 2 0 0 2 2 2 0 MDM2-binding Phage_Mu_Gam PF07352.7 KEG08024.1 - 2.7 7.5 8.1 2.3 7.7 1.4 2.3 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein FH2 PF02181.18 KEG08025.1 - 8.1e-50 169.7 0.0 1.2e-49 169.1 0.0 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain Reo_sigmaC PF04582.7 KEG08027.1 - 0.00011 21.5 6.1 0.14 11.3 0.0 3.9 2 1 0 3 3 3 2 Reovirus sigma C capsid protein Tropomyosin PF00261.15 KEG08027.1 - 0.015 14.4 0.4 0.015 14.4 0.3 6.8 5 1 2 7 7 7 0 Tropomyosin DivIC PF04977.10 KEG08027.1 - 0.03 13.7 0.3 0.03 13.7 0.2 9.4 8 2 1 10 10 10 0 Septum formation initiator ATG16 PF08614.6 KEG08027.1 - 0.041 13.7 0.4 0.041 13.7 0.3 7.3 5 2 2 7 7 7 0 Autophagy protein 16 (ATG16) DUF641 PF04859.7 KEG08027.1 - 0.1 12.3 45.3 3.5 7.3 0.0 9.0 6 2 2 8 8 8 0 Plant protein of unknown function (DUF641) RPW8 PF05659.6 KEG08027.1 - 1.9 8.0 7.0 23 4.4 0.4 3.6 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF1664 PF07889.7 KEG08027.1 - 2.2 8.1 16.5 0.94 9.2 1.4 5.8 5 2 1 6 6 6 0 Protein of unknown function (DUF1664) GAS PF13851.1 KEG08027.1 - 2.9 7.0 0.0 2.9 7.0 0.0 6.6 6 1 1 7 7 7 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 KEG08027.1 - 4.2 7.2 69.6 0.68 9.7 0.6 8.5 5 2 2 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PH PF00169.24 KEG08028.1 - 0.079 13.1 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 PH domain Myc_N PF01056.13 KEG08028.1 - 3.1 6.8 13.6 0.18 10.9 2.8 2.5 3 0 0 3 3 3 0 Myc amino-terminal region PK_C PF02887.11 KEG08029.1 - 0.12 11.9 0.1 0.13 11.8 0.1 1.1 1 0 0 1 1 1 0 Pyruvate kinase, alpha/beta domain Cullin_Nedd8 PF10557.4 KEG08030.1 - 0.039 13.7 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 Cullin protein neddylation domain TPR_19 PF14559.1 KEG08030.1 - 0.043 14.1 1.5 9 6.7 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 KEG08030.1 - 0.075 12.6 0.7 0.31 10.6 0.2 2.2 2 0 0 2 2 2 0 TPR repeat TPR_2 PF07719.12 KEG08030.1 - 0.09 12.7 6.4 0.65 10.0 0.6 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 KEG08030.1 - 4.7 6.9 6.2 4.6 7.0 0.6 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat RNase_H2-Ydr279 PF09468.5 KEG08032.1 - 0.013 14.7 15.9 0.16 11.1 2.0 2.2 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) Neur_chan_memb PF02932.11 KEG08032.1 - 0.72 9.6 16.8 0.01 15.7 3.1 2.2 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SRP-alpha_N PF04086.8 KEG08032.1 - 3.6 6.8 26.1 0.85 8.9 2.0 2.5 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal RskA PF10099.4 KEG08033.1 - 0.012 15.3 1.7 0.013 15.2 1.1 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Phage_rep_O PF04492.8 KEG08033.1 - 0.14 12.4 0.0 0.16 12.2 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage replication protein O DUF3017 PF11222.3 KEG08033.1 - 0.16 11.7 3.6 0.23 11.2 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3017) SHS2_Rpb7-N PF03876.12 KEG08034.1 - 1.2e-15 57.3 0.0 2e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 CRAL_TRIO PF00650.15 KEG08035.1 - 1.2e-29 102.8 0.0 1.8e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KEG08035.1 - 1.3e-06 28.3 0.1 3.1e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain UBA_4 PF14555.1 KEG08035.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain CRAL_TRIO PF00650.15 KEG08036.1 - 1.7e-33 115.3 0.0 2.4e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 KEG08036.1 - 7.2e-05 22.7 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KEG08036.1 - 0.0004 20.4 0.0 0.001 19.1 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Ribosomal_L13 PF00572.13 KEG08036.1 - 0.016 15.2 0.0 8.5 6.4 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein L13 DUF342 PF03961.8 KEG08038.1 - 0.025 12.9 2.3 0.034 12.5 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 KEG08038.1 - 0.035 11.9 2.7 0.042 11.7 1.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CHASE3 PF05227.8 KEG08038.1 - 0.038 13.6 4.8 1.8 8.2 1.3 2.6 1 1 1 2 2 2 0 CHASE3 domain RNF111_N PF15303.1 KEG08038.1 - 0.25 10.8 2.9 0.33 10.4 2.0 1.1 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus DUF948 PF06103.6 KEG08038.1 - 0.27 11.1 0.9 0.54 10.1 0.7 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF904 PF06005.7 KEG08038.1 - 0.29 11.4 10.0 2.8 8.2 2.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF3154 PF11351.3 KEG08038.1 - 0.5 10.1 5.2 0.83 9.4 0.8 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3154) Ax_dynein_light PF10211.4 KEG08038.1 - 1 9.1 12.9 1.9 8.2 3.8 2.3 1 1 1 2 2 2 0 Axonemal dynein light chain Myc_N PF01056.13 KEG08040.1 - 0.065 12.4 0.3 0.073 12.2 0.2 1.0 1 0 0 1 1 1 0 Myc amino-terminal region Ribonuclease_3 PF00636.21 KEG08041.1 - 0.00044 20.6 0.1 0.0041 17.5 0.1 2.6 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KEG08041.1 - 0.022 14.7 0.1 0.33 10.9 0.0 2.4 1 1 0 1 1 1 0 Ribonuclease-III-like rve_3 PF13683.1 KEG08041.1 - 0.097 12.2 0.6 0.32 10.5 0.1 2.0 2 0 0 2 2 2 0 Integrase core domain Metallophos PF00149.23 KEG08042.1 - 3.2e-41 140.9 0.4 4.5e-41 140.4 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RNA_pol_N PF01194.12 KEG08043.1 - 5.7e-28 96.7 0.7 6.7e-28 96.4 0.5 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Yippee-Mis18 PF03226.9 KEG08043.1 - 0.1 12.6 0.9 0.14 12.2 0.6 1.3 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Hamartin PF04388.7 KEG08044.1 - 0.018 13.7 1.8 0.019 13.6 1.3 1.0 1 0 0 1 1 1 0 Hamartin protein DUF4483 PF14825.1 KEG08044.1 - 0.048 13.3 0.2 0.056 13.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4483) GCN5L1 PF06320.8 KEG08044.1 - 0.11 12.3 0.4 0.18 11.6 0.3 1.4 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) DUF1180 PF06679.7 KEG08044.1 - 0.16 11.8 2.7 0.19 11.6 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) BT1 PF03092.11 KEG08045.1 - 2.4e-141 471.3 11.2 3e-141 471.0 7.8 1.0 1 0 0 1 1 1 1 BT1 family Glyco_transf_28 PF03033.15 KEG08045.1 - 0.00051 19.8 0.0 0.0013 18.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UPF0172 PF03665.8 KEG08046.1 - 8.2e-56 188.5 0.2 1e-55 188.3 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.16 KEG08046.1 - 0.019 14.7 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease LRR_4 PF12799.2 KEG08047.1 - 8.4e-05 22.1 0.7 0.0022 17.5 0.8 2.4 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG08047.1 - 0.0005 19.7 0.5 0.0012 18.5 0.3 1.6 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 KEG08047.1 - 0.0051 16.6 6.7 0.0075 16.1 0.6 3.5 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.1 KEG08047.1 - 0.052 13.6 0.5 1.9 8.7 0.2 3.2 4 0 0 4 4 4 0 Leucine Rich repeat LRR_7 PF13504.1 KEG08047.1 - 0.16 12.2 2.3 1.3 9.5 0.1 3.4 3 0 0 3 3 3 0 Leucine rich repeat DUF1180 PF06679.7 KEG08047.1 - 6.2 6.6 7.1 3.9 7.3 3.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) WD40 PF00400.27 KEG08049.1 - 1.1e-19 69.4 17.1 1.6e-06 27.7 0.1 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat PQQ_3 PF13570.1 KEG08049.1 - 0.0099 16.1 1.3 1 9.6 0.0 4.1 3 1 1 4 4 4 1 PQQ-like domain DUF2205 PF10224.4 KEG08050.1 - 0.012 15.2 1.9 0.012 15.2 1.3 3.8 4 0 0 4 4 4 0 Predicted coiled-coil protein (DUF2205) NBP1 PF08537.5 KEG08050.1 - 0.46 9.6 10.7 0.46 9.6 1.6 2.3 2 0 0 2 2 2 0 Fungal Nap binding protein NBP1 Syntaxin-6_N PF09177.6 KEG08050.1 - 0.52 10.7 9.0 2.2 8.7 0.8 3.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Shugoshin_N PF07558.6 KEG08050.1 - 0.61 9.8 4.1 0.29 10.8 0.6 2.2 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region TACC PF05010.9 KEG08050.1 - 0.82 9.3 12.5 0.43 10.3 4.8 2.2 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) APG6 PF04111.7 KEG08050.1 - 1.7 7.5 27.7 0.43 9.5 6.2 3.1 3 0 0 3 3 3 0 Autophagy protein Apg6 ATG16 PF08614.6 KEG08050.1 - 2 8.2 29.5 3.3 7.4 0.8 4.0 1 1 1 3 3 3 0 Autophagy protein 16 (ATG16) MEF2_binding PF09047.5 KEG08051.1 - 0.056 13.0 8.0 0.071 12.7 0.4 3.1 2 0 0 2 2 2 0 MEF2 binding Mucin PF01456.12 KEG08052.1 - 6.2 6.5 25.3 1.5e+03 -1.2 17.5 2.8 1 1 0 1 1 1 0 Mucin-like glycoprotein DUF2207 PF09972.4 KEG08054.1 - 3.2 6.2 5.6 4.7 5.6 3.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Heme_oxygenase PF01126.15 KEG08057.1 - 0.054 13.0 0.1 0.056 13.0 0.0 1.1 1 0 0 1 1 1 0 Heme oxygenase zf-C3HC4_3 PF13920.1 KEG08061.1 - 1.1e-09 37.7 4.9 1.1e-09 37.7 3.4 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEG08061.1 - 1.2e-09 37.6 5.9 1.2e-09 37.6 4.1 2.7 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEG08061.1 - 7.9e-09 35.2 6.4 7.9e-09 35.2 4.5 2.7 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KEG08061.1 - 8.1e-09 35.3 6.6 8.1e-09 35.3 4.6 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEG08061.1 - 6.7e-07 28.9 7.0 6.7e-07 28.9 4.8 2.8 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KEG08061.1 - 2.3e-06 27.3 4.3 2.3e-06 27.3 3.0 3.3 3 1 1 4 4 3 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KEG08061.1 - 0.00034 20.6 7.9 0.0039 17.2 4.0 3.0 2 1 0 2 2 2 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KEG08061.1 - 0.00065 19.3 1.0 0.00065 19.3 0.7 2.7 2 1 0 2 2 2 1 RING-type zinc-finger zf-MIZ PF02891.15 KEG08061.1 - 0.0032 16.9 8.4 0.013 15.0 3.4 2.5 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Di19 PF05605.7 KEG08061.1 - 0.0053 16.8 6.6 0.017 15.2 0.2 2.8 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-Apc11 PF12861.2 KEG08061.1 - 0.018 14.8 3.4 0.026 14.3 0.7 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 KEG08061.1 - 0.05 13.1 5.2 0.05 13.1 1.3 2.3 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit FdhE PF04216.7 KEG08061.1 - 0.38 10.4 10.2 3.3 7.3 7.1 2.7 2 1 0 2 2 2 0 Protein involved in formate dehydrogenase formation Rad50_zn_hook PF04423.9 KEG08061.1 - 0.48 9.9 7.1 5.1 6.6 0.1 3.0 3 0 0 3 3 3 0 Rad50 zinc hook motif CitX PF03802.9 KEG08061.1 - 0.73 9.2 5.1 8.9 5.7 0.5 2.2 2 0 0 2 2 2 0 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase GAGA PF09237.6 KEG08061.1 - 0.83 9.2 6.5 8.6 6.0 0.2 3.5 3 0 0 3 3 3 0 GAGA factor DUF2256 PF10013.4 KEG08061.1 - 2.7 7.8 6.5 18 5.1 0.2 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) FYVE PF01363.16 KEG08061.1 - 4.5 7.2 13.9 47 3.9 7.7 3.2 2 1 0 2 2 2 0 FYVE zinc finger OTT_1508_deam PF14441.1 KEG08061.1 - 6 6.6 6.6 4.4e+02 0.6 4.6 2.5 1 1 0 1 1 1 0 OTT_1508-like deaminase Prok-RING_2 PF14445.1 KEG08061.1 - 9.3 6.2 12.9 4 7.4 0.2 3.9 3 1 1 4 4 4 0 Prokaryotic RING finger family 2 tRNA-synt_1g PF09334.6 KEG08065.1 - 4.9e-113 377.7 0.0 6.5e-113 377.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KEG08065.1 - 6.4e-20 70.7 0.4 1.5e-10 39.7 0.3 2.5 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 KEG08065.1 - 8.1e-08 31.7 0.0 0.002 17.3 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 KEG08065.1 - 0.057 12.2 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (R) MKT1_N PF12247.3 KEG08066.1 - 9e-19 67.5 0.1 1.7e-18 66.7 0.1 1.5 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_C PF12246.3 KEG08066.1 - 9.6e-13 47.6 0.0 1.8e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication LdpA_C PF12617.3 KEG08066.1 - 0.24 10.6 0.0 0.5 9.6 0.0 1.4 1 0 0 1 1 1 0 Iron-Sulfur binding protein C terminal BAF1_ABF1 PF04684.8 KEG08066.1 - 3 6.6 10.4 5.1 5.8 7.2 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Mito_fiss_reg PF05308.6 KEG08067.1 - 0.081 12.2 6.1 0.12 11.7 4.2 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF605 PF04652.11 KEG08067.1 - 1.2 8.4 12.0 1.5 8.1 8.3 1.1 1 0 0 1 1 1 0 Vta1 like DnaJ PF00226.26 KEG08072.1 - 5.6e-14 51.6 0.1 8.6e-14 51.0 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.8 KEG08072.1 - 3.8e-05 23.1 7.9 0.00013 21.3 5.5 1.9 1 1 0 1 1 1 1 CSL zinc finger NADH-G_4Fe-4S_3 PF10588.4 KEG08073.1 - 7.3e-17 60.3 0.3 7.3e-17 60.3 0.2 2.3 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.1 KEG08073.1 - 1.9e-11 43.5 0.1 4.6e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.22 KEG08073.1 - 2.1e-08 33.8 0.5 5.7e-08 32.4 0.1 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.1 KEG08073.1 - 0.013 15.8 3.4 0.037 14.4 2.4 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_2 PF12797.2 KEG08073.1 - 0.16 11.9 0.2 0.16 11.9 0.1 2.5 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_7 PF12838.2 KEG08073.1 - 0.22 11.9 8.0 0.087 13.2 1.8 2.8 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 KEG08073.1 - 2.3 8.5 8.0 0.43 10.8 2.1 2.4 3 0 0 3 3 3 0 4Fe-4S dicluster domain zf-C3HC4_3 PF13920.1 KEG08073.1 - 2.6 7.7 8.7 16 5.2 0.0 3.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF485 PF04341.7 KEG08075.1 - 0.096 12.4 0.1 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF485 ECH PF00378.15 KEG08078.1 - 3.4e-46 157.3 0.2 5.4e-46 156.6 0.1 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family 3HCDH_N PF02737.13 KEG08078.1 - 1.8e-43 148.2 0.0 3.4e-43 147.4 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KEG08078.1 - 1.4e-24 86.2 0.0 7.8e-16 58.2 0.0 2.8 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain TrkA_N PF02254.13 KEG08078.1 - 0.022 14.7 0.1 0.077 13.0 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain Apolipoprotein PF01442.13 KEG08079.1 - 0.11 11.9 4.3 0.22 11.0 3.0 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Podoplanin PF05808.6 KEG08080.1 - 4 6.9 9.1 11 5.5 6.3 1.7 1 0 0 1 1 1 0 Podoplanin zf-C3HC4 PF00097.20 KEG08081.1 - 0.0015 18.1 12.6 0.0015 18.1 8.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEG08081.1 - 0.014 15.1 14.4 0.014 15.1 10.0 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KEG08081.1 - 0.016 15.2 16.5 0.046 13.7 11.5 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEG08081.1 - 2 8.3 20.8 1.7 8.5 12.9 2.1 2 1 0 2 2 2 0 Ring finger domain DDRGK PF09756.4 KEG08081.1 - 4.2 6.7 7.5 0.24 10.7 1.1 1.9 2 0 0 2 2 2 0 DDRGK domain Meckelin PF09773.4 KEG08082.1 - 8.2e-278 923.7 0.0 9.3e-278 923.5 0.0 1.0 1 0 0 1 1 1 1 Meckelin (Transmembrane protein 67) TPR_20 PF14561.1 KEG08083.1 - 3.5e-05 23.8 0.1 0.00023 21.2 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEG08083.1 - 4.8e-05 22.9 0.1 0.72 9.9 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEG08083.1 - 0.00038 21.0 0.8 1.8 9.3 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 KEG08083.1 - 0.0016 18.7 0.8 0.84 10.2 0.0 4.0 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 KEG08083.1 - 0.0044 16.9 0.8 0.042 13.7 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF4192 PF13830.1 KEG08083.1 - 0.007 16.0 0.1 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4192) Thioredoxin PF00085.15 KEG08083.1 - 0.0078 15.8 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin TPR_19 PF14559.1 KEG08083.1 - 0.016 15.5 0.5 2.1 8.7 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 KEG08083.1 - 0.021 14.3 0.1 5.4 6.7 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 KEG08083.1 - 0.035 13.7 1.4 1.4 8.5 0.1 3.5 3 1 0 3 3 3 0 TPR repeat DLH PF01738.13 KEG08086.1 - 0.037 13.3 0.0 0.038 13.2 0.0 1.1 1 0 0 1 1 1 0 Dienelactone hydrolase family HCaRG PF07258.9 KEG08087.1 - 5e-06 26.1 0.0 6e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 HCaRG protein Exo_endo_phos PF03372.18 KEG08089.1 - 9.5e-20 71.5 0.0 1.3e-19 71.1 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KEG08089.1 - 0.0051 16.4 0.0 0.016 14.8 0.0 1.8 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase GspL_C PF12693.2 KEG08089.1 - 0.052 13.3 1.7 0.1 12.3 1.2 1.4 1 0 0 1 1 1 0 GspL periplasmic domain Syndecan PF01034.15 KEG08090.1 - 0.079 12.6 0.0 0.079 12.6 0.0 3.2 2 0 0 2 2 2 0 Syndecan domain DUF1418 PF07214.7 KEG08090.1 - 0.1 12.2 2.6 0.37 10.4 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1418) Vps52 PF04129.7 KEG08091.1 - 0.01 14.4 0.1 0.028 12.9 0.0 1.6 2 0 0 2 2 2 0 Vps52 / Sac2 family DUF2069 PF09842.4 KEG08091.1 - 1.1 9.2 8.1 6.7 6.7 0.7 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2069) SMP PF04927.7 KEG08095.1 - 0.022 14.7 3.2 1.9 8.4 0.1 2.3 2 0 0 2 2 2 0 Seed maturation protein SelB-wing_2 PF09106.6 KEG08095.1 - 0.044 13.7 0.5 3.4 7.6 0.0 2.8 2 0 0 2 2 2 0 Elongation factor SelB, winged helix R3H PF01424.17 KEG08095.1 - 0.96 9.1 5.2 30 4.3 0.0 3.7 4 0 0 4 4 4 0 R3H domain MdcG PF10620.4 KEG08095.1 - 0.98 8.9 4.1 9.5 5.6 0.2 2.1 2 0 0 2 2 2 0 Phosphoribosyl-dephospho-CoA transferase MdcG Ste5 PF11610.3 KEG08095.1 - 1.1 8.8 5.9 10 5.7 0.1 2.8 3 0 0 3 3 3 0 Scaffold protein Ste5-Fus5 binding region Pep_deformylase PF01327.16 KEG08097.1 - 5.4e-27 94.1 0.0 9e-27 93.3 0.0 1.4 1 0 0 1 1 1 1 Polypeptide deformylase Retinal PF15449.1 KEG08097.1 - 0.0053 14.4 3.4 0.0062 14.2 2.3 1.0 1 0 0 1 1 1 1 Retinal protein Vfa1 PF08432.5 KEG08097.1 - 1.3 8.9 9.0 1.8 8.5 6.2 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Daxx PF03344.10 KEG08097.1 - 6.3 5.1 17.1 8.1 4.7 11.9 1.0 1 0 0 1 1 1 0 Daxx Family Pescadillo_N PF06732.6 KEG08098.1 - 3.5e-95 318.4 4.4 3.5e-95 318.4 3.1 1.7 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 KEG08098.1 - 1.8e-08 34.3 0.0 5.3e-08 32.9 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain OTCace_N PF02729.16 KEG08103.1 - 1.3e-41 141.5 0.1 2.5e-41 140.6 0.1 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 KEG08103.1 - 5.6e-36 123.7 0.6 3e-35 121.4 0.2 1.9 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Pribosyltran PF00156.22 KEG08104.1 - 1.9e-17 63.1 4.4 7.3e-17 61.2 3.0 1.8 1 1 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.1 KEG08104.1 - 7e-05 22.2 0.0 9.6e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase UPRTase PF14681.1 KEG08104.1 - 0.00015 21.0 0.0 0.00018 20.7 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DXP_synthase_N PF13292.1 KEG08104.1 - 0.048 12.5 0.0 0.059 12.3 0.0 1.1 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase P5-ATPase PF12409.3 KEG08105.1 - 0.057 13.2 0.0 0.073 12.9 0.0 1.1 1 0 0 1 1 1 0 P5-type ATPase cation transporter Proteasome PF00227.21 KEG08106.1 - 1.3e-30 106.1 0.0 1.6e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF1768 PF08719.6 KEG08107.1 - 9.5e-37 126.1 0.0 1.1e-36 125.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) DnaG_DnaB_bind PF08278.6 KEG08107.1 - 0.066 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding Pro_isomerase PF00160.16 KEG08108.1 - 6.3e-52 175.8 3.1 7e-41 140.0 0.8 2.0 1 1 1 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ComC PF03047.9 KEG08108.1 - 0.5 9.8 3.6 18 4.8 0.2 3.2 3 0 0 3 3 3 0 COMC family CytochromB561_N PF09786.4 KEG08109.1 - 2.4e-08 32.9 0.2 1.1e-05 24.1 0.0 2.2 1 1 1 2 2 2 2 Cytochrome B561, N terminal DUF3138 PF11336.3 KEG08109.1 - 1.5 6.9 9.4 4.1 5.4 3.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) SlyX PF04102.7 KEG08111.1 - 4.7e-06 26.8 1.3 0.0097 16.2 0.1 2.1 2 0 0 2 2 2 2 SlyX DivIC PF04977.10 KEG08111.1 - 0.0046 16.4 2.0 1.3 8.5 0.3 2.1 2 0 0 2 2 2 2 Septum formation initiator Secretin_N PF03958.12 KEG08111.1 - 0.0064 16.6 0.6 0.009 16.1 0.4 1.3 1 0 0 1 1 1 1 Bacterial type II/III secretion system short domain ATG16 PF08614.6 KEG08111.1 - 0.011 15.5 1.1 0.013 15.3 0.8 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Paramyx_P_V_C PF03210.8 KEG08111.1 - 0.019 14.8 1.2 0.044 13.6 0.3 1.7 1 1 1 2 2 2 0 Paramyxovirus P/V phosphoprotein C-terminal TMF_TATA_bd PF12325.3 KEG08111.1 - 0.02 14.5 0.4 0.088 12.5 0.1 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding FliJ PF02050.11 KEG08111.1 - 0.034 14.1 0.1 0.65 10.0 0.0 2.0 2 0 0 2 2 2 0 Flagellar FliJ protein DUF4407 PF14362.1 KEG08111.1 - 0.035 13.0 2.9 0.046 12.6 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TSC22 PF01166.13 KEG08111.1 - 0.058 13.3 0.1 4.2 7.4 0.0 2.1 2 0 0 2 2 2 0 TSC-22/dip/bun family Spectrin PF00435.16 KEG08111.1 - 0.074 13.3 1.2 5.4 7.3 0.1 2.0 1 1 1 2 2 2 0 Spectrin repeat DUF4140 PF13600.1 KEG08111.1 - 0.11 13.0 6.1 0.55 10.7 0.8 2.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Reo_sigmaC PF04582.7 KEG08111.1 - 0.18 10.9 1.2 0.21 10.7 0.8 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF3138 PF11336.3 KEG08111.1 - 0.44 8.6 5.5 0.46 8.5 3.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) HrpB7 PF09486.5 KEG08111.1 - 0.69 9.8 9.1 26 4.7 6.3 2.1 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) BMFP PF04380.8 KEG08111.1 - 1.1 9.4 4.0 0.82 9.8 0.6 2.0 2 0 0 2 2 2 0 Membrane fusogenic activity ROS_MUCR PF05443.6 KEG08111.1 - 1.5 8.6 3.7 2.9 7.6 0.7 1.9 1 1 1 2 2 2 0 ROS/MUCR transcriptional regulator protein DUF1192 PF06698.6 KEG08111.1 - 1.9 8.3 6.2 9.2 6.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF4164 PF13747.1 KEG08111.1 - 2.4 8.3 6.0 25 5.1 4.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) TAF4 PF05236.9 KEG08112.1 - 0.012 14.9 0.2 0.018 14.3 0.2 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Cullin_Nedd8 PF10557.4 KEG08115.1 - 7.3e-16 57.7 0.5 1.7e-15 56.5 0.4 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain Cullin PF00888.17 KEG08115.1 - 1.1e-14 53.8 0.0 2.1e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Cullin family MarR_2 PF12802.2 KEG08115.1 - 0.003 17.1 0.7 0.21 11.2 0.0 3.5 3 0 0 3 3 3 1 MarR family HTH_24 PF13412.1 KEG08115.1 - 0.099 12.0 0.0 0.39 10.1 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Pkinase PF00069.20 KEG08117.1 - 1.2e-40 139.3 0.0 1.1e-39 136.1 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG08117.1 - 5.8e-26 91.1 0.0 1.6e-22 79.8 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KEG08117.1 - 5.4e-05 22.3 0.0 8.7e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Glyco_transf_15 PF01793.11 KEG08119.1 - 1.1e-39 136.3 0.0 1.4e-39 135.9 0.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF1456 PF07308.8 KEG08119.1 - 0.076 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1456) Glyco_transf_15 PF01793.11 KEG08120.1 - 2.8e-10 39.6 0.0 3e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Evr1_Alr PF04777.8 KEG08121.1 - 3.8e-22 77.9 0.6 6.9e-22 77.1 0.4 1.4 1 0 0 1 1 1 1 Erv1 / Alr family ThiF PF00899.16 KEG08122.1 - 5.6e-35 120.1 0.0 1e-34 119.2 0.0 1.5 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 KEG08122.1 - 1.9e-07 30.5 0.3 5.1e-07 29.2 0.2 1.8 1 0 0 1 1 1 1 MoeZ/MoeB domain ApbA PF02558.11 KEG08122.1 - 0.0015 17.9 0.4 0.0051 16.2 0.0 2.2 3 1 0 3 3 3 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 KEG08122.1 - 0.0017 18.4 0.4 0.0046 17.0 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 KEG08122.1 - 0.0019 17.3 0.0 0.0046 16.1 0.0 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 KEG08122.1 - 0.0074 15.9 0.4 0.032 13.8 0.0 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KEG08122.1 - 0.013 15.2 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 KEG08122.1 - 0.017 14.5 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Saccharop_dh PF03435.13 KEG08122.1 - 0.04 12.9 0.0 0.072 12.0 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase TrkA_N PF02254.13 KEG08122.1 - 0.058 13.3 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.1 KEG08122.1 - 0.11 12.7 0.1 0.4 10.9 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding Rad9 PF04139.8 KEG08123.1 - 2.2e-08 33.5 0.0 7.4e-08 31.8 0.0 1.8 1 1 0 1 1 1 1 Rad9 Fer4_8 PF13183.1 KEG08124.1 - 0.00018 21.4 0.3 0.00045 20.1 0.2 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.1 KEG08124.1 - 0.00026 21.2 0.3 0.00055 20.2 0.2 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 KEG08124.1 - 0.0023 18.1 0.1 0.0057 16.8 0.1 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 KEG08124.1 - 0.0048 16.6 0.3 0.011 15.5 0.2 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 KEG08124.1 - 0.0055 17.0 1.0 0.039 14.3 0.7 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.2 KEG08124.1 - 0.025 14.8 1.1 0.11 12.9 0.8 2.0 1 0 0 1 1 1 0 4Fe-4S binding domain Ribosomal_L6e PF01159.14 KEG08125.1 - 8.3e-32 109.6 0.3 8.3e-32 109.6 0.2 2.0 2 1 0 2 2 2 1 Ribosomal protein L6e KOW PF00467.24 KEG08125.1 - 0.0053 16.4 0.1 0.04 13.6 0.0 2.5 3 0 0 3 3 3 1 KOW motif DUF2823 PF11034.3 KEG08125.1 - 8.4 6.6 12.8 0.63 10.2 3.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2823) DUF4471 PF14740.1 KEG08128.1 - 1.8e-85 286.6 0.1 2.4e-85 286.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) DUF4470 PF14737.1 KEG08128.1 - 5.6e-20 70.9 0.0 1.8e-19 69.3 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) Metallophos PF00149.23 KEG08130.1 - 0.039 13.3 0.0 0.16 11.3 0.0 2.0 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase DUF3060 PF11259.3 KEG08131.1 - 0.014 15.0 5.5 0.99 9.0 1.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3060) DUF2217 PF10265.4 KEG08131.1 - 9.6 4.8 6.9 11 4.5 4.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Rad1 PF02144.11 KEG08132.1 - 5.3e-08 31.9 0.0 4.2e-07 29.0 0.0 1.9 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Flu_NS2 PF00601.14 KEG08136.1 - 0.035 14.3 0.2 0.045 13.9 0.1 1.2 1 0 0 1 1 1 0 Influenza non-structural protein (NS2) TPR_11 PF13414.1 KEG08138.1 - 3.7e-14 52.1 30.2 1.5e-08 34.1 1.1 6.6 5 1 1 6 6 6 4 TPR repeat TPR_2 PF07719.12 KEG08138.1 - 4.8e-07 29.2 36.3 0.037 13.9 0.4 9.0 10 0 0 10 10 8 4 Tetratricopeptide repeat TPR_12 PF13424.1 KEG08138.1 - 8e-06 25.7 40.3 0.26 11.2 2.0 7.7 4 2 5 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.1 KEG08138.1 - 3.6e-05 23.2 7.3 0.024 14.4 0.1 6.0 6 0 0 6 6 5 1 Tetratricopeptide repeat PspA_IM30 PF04012.7 KEG08138.1 - 0.002 17.5 8.5 0.002 17.5 5.9 2.4 2 0 0 2 2 2 1 PspA/IM30 family TPR_1 PF00515.23 KEG08138.1 - 0.0022 17.5 19.3 0.21 11.2 0.5 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat Zwint PF15556.1 KEG08138.1 - 0.0044 16.2 2.0 0.0044 16.2 1.4 1.8 2 0 0 2 2 2 1 ZW10 interactor TPR_9 PF13371.1 KEG08138.1 - 0.0049 16.6 20.3 0.0051 16.6 0.3 5.6 3 2 3 6 6 6 1 Tetratricopeptide repeat MbeB_N PF04837.7 KEG08138.1 - 0.005 16.9 0.3 0.023 14.7 0.0 2.3 2 0 0 2 2 1 1 MbeB-like, N-term conserved region DUF2225 PF09986.4 KEG08138.1 - 0.032 13.6 4.7 4.1 6.8 1.1 2.9 2 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) Chorion_2 PF03964.10 KEG08138.1 - 0.13 12.8 5.0 0.25 11.9 1.7 2.7 2 0 0 2 2 2 0 Chorion family 2 TPR_16 PF13432.1 KEG08138.1 - 0.14 12.8 48.5 1.8 9.3 0.8 7.3 5 2 4 9 9 8 0 Tetratricopeptide repeat TPR_7 PF13176.1 KEG08138.1 - 0.46 10.4 14.2 2 8.4 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat AKNA PF12443.3 KEG08138.1 - 0.69 9.9 5.5 0.32 11.0 0.1 3.3 3 1 1 4 4 4 0 AT-hook-containing transcription factor TPR_19 PF14559.1 KEG08138.1 - 6.2 7.2 23.4 0.65 10.3 0.4 5.6 5 1 0 5 5 5 0 Tetratricopeptide repeat mono-CXXC PF15626.1 KEG08139.1 - 0.021 14.7 0.7 0.073 13.0 0.5 1.9 1 0 0 1 1 1 0 single CXXC unit Sulfate_tra_GLY PF13792.1 KEG08140.1 - 0.03 13.9 3.1 0.047 13.3 2.2 1.4 1 0 0 1 1 1 0 Sulfate transporter N-terminal domain with GLY motif Rap1_C PF11626.3 KEG08140.1 - 0.25 11.2 1.0 0.3 10.9 0.0 1.7 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Foamy_virus_ENV PF03408.9 KEG08140.1 - 0.45 7.9 4.0 0.51 7.8 2.7 1.0 1 0 0 1 1 1 0 Foamy virus envelope protein Shisa PF13908.1 KEG08140.1 - 2.2 8.4 4.3 2.8 8.1 2.9 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF2450 PF10475.4 KEG08142.1 - 1.3e-20 73.5 7.0 2.6e-20 72.5 4.8 1.5 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) DUF2451 PF10474.4 KEG08142.1 - 0.00011 22.0 1.3 0.00048 19.9 0.1 2.5 3 0 0 3 3 3 1 Protein of unknown function C-terminus (DUF2451) Glyco_transf_8 PF01501.15 KEG08145.1 - 5.1e-09 35.8 0.2 1.8e-07 30.7 0.0 2.2 1 1 0 2 2 2 2 Glycosyl transferase family 8 Foamy_virus_ENV PF03408.9 KEG08145.1 - 0.17 9.4 0.1 0.29 8.6 0.1 1.3 1 0 0 1 1 1 0 Foamy virus envelope protein FtsX PF02687.16 KEG08147.1 - 1.4e-27 95.8 36.3 3.3e-17 62.3 8.1 4.8 4 2 0 4 4 4 2 FtsX-like permease family MacB_PCD PF12704.2 KEG08147.1 - 0.42 10.1 0.0 0.18 11.3 0.1 4.1 4 1 0 4 4 4 0 MacB-like periplasmic core domain LRR_4 PF12799.2 KEG08151.1 - 1e-57 190.9 17.5 0.00073 19.1 0.2 20.3 7 5 12 21 21 21 18 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG08151.1 - 3.5e-23 81.1 34.5 0.045 13.5 1.1 13.7 10 2 6 16 16 16 12 Leucine rich repeat LRR_6 PF13516.1 KEG08151.1 - 1.9e-18 64.4 40.6 0.061 13.4 0.0 19.9 23 2 3 26 26 26 5 Leucine Rich repeat LRR_1 PF00560.28 KEG08151.1 - 1.2e-11 42.9 35.1 9.7 6.6 0.3 20.9 22 5 1 23 23 23 1 Leucine Rich Repeat LRR_5 PF13306.1 KEG08151.1 - 0.0059 16.3 0.6 4.2 7.0 0.1 5.0 6 1 0 6 6 6 1 Leucine rich repeats (6 copies) BESS PF02944.15 KEG08151.1 - 0.24 10.9 3.8 2.9 7.5 0.1 2.9 2 0 0 2 2 2 0 BESS motif Fer2_BFD PF04324.10 KEG08152.1 - 0.33 11.0 2.2 13 5.8 0.3 2.9 2 1 0 2 2 2 0 BFD-like [2Fe-2S] binding domain Tymo_coat PF00983.13 KEG08152.1 - 3.9 7.1 8.5 9.2 5.9 1.7 2.1 1 1 1 2 2 2 0 Tymovirus coat protein WD40 PF00400.27 KEG08153.1 - 7.5e-20 70.0 12.3 2e-06 27.4 0.0 6.8 7 0 0 7 7 7 3 WD domain, G-beta repeat Sec16_C PF12931.2 KEG08153.1 - 0.00025 20.9 0.7 0.0019 17.9 0.0 2.4 2 1 0 2 2 2 1 Sec23-binding domain of Sec16 Spt20 PF12090.3 KEG08153.1 - 0.0039 16.5 5.2 0.0084 15.4 3.6 1.5 1 0 0 1 1 1 1 Spt20 family TPR_2 PF07719.12 KEG08153.1 - 0.03 14.2 0.1 0.31 11.0 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat FAM60A PF15396.1 KEG08153.1 - 1.4 8.6 4.5 2.3 7.9 3.1 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Gti1_Pac2 PF09729.4 KEG08153.1 - 2.5 7.9 6.2 4.7 7.0 4.3 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family Ycf1 PF05758.7 KEG08153.1 - 8.8 3.9 9.7 12 3.4 6.8 1.1 1 0 0 1 1 1 0 Ycf1 MORN PF02493.15 KEG08154.1 - 2e-21 74.3 23.3 1.2e-05 24.7 0.2 6.9 6 0 0 6 6 6 6 MORN repeat DEAD PF00270.24 KEG08155.1 - 8.5e-36 122.9 0.0 2e-35 121.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEG08155.1 - 4.6e-19 68.0 0.0 9.9e-19 66.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KEG08155.1 - 0.00036 19.4 0.0 0.00074 18.4 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SecA_DEAD PF07517.9 KEG08155.1 - 0.0019 17.5 0.0 0.026 13.8 0.0 2.4 2 0 0 2 2 2 1 SecA DEAD-like domain AAA_22 PF13401.1 KEG08155.1 - 0.0061 16.7 0.1 0.069 13.2 0.0 2.9 3 1 0 3 3 3 1 AAA domain ResIII PF04851.10 KEG08155.1 - 0.057 13.2 0.0 0.3 10.8 0.0 2.2 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Adaptin_N PF01602.15 KEG08156.1 - 2.7e-83 280.1 0.3 2e-75 254.1 0.0 2.1 1 1 1 2 2 2 2 Adaptin N terminal region HEAT_2 PF13646.1 KEG08156.1 - 1.2e-05 25.4 0.7 0.39 11.0 0.1 3.9 3 2 0 3 3 3 2 HEAT repeats Cnd1 PF12717.2 KEG08156.1 - 4.8e-05 23.2 1.0 0.45 10.3 0.2 3.0 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KEG08156.1 - 0.00017 21.3 3.6 13 6.1 0.0 5.9 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 KEG08156.1 - 0.012 16.1 8.2 1.8 9.1 0.0 4.8 6 0 0 6 6 6 0 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KEG08156.1 - 0.073 13.4 0.1 2 8.8 0.0 3.0 2 1 0 2 2 2 0 Vacuolar 14 Fab1-binding region Pex14_N PF04695.8 KEG08157.1 - 0.11 12.5 3.7 0.16 11.9 2.6 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.9 KEG08157.1 - 0.16 11.6 1.0 0.22 11.2 0.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) BAF1_ABF1 PF04684.8 KEG08157.1 - 0.16 10.7 8.6 0.2 10.4 6.0 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor gpUL132 PF11359.3 KEG08157.1 - 0.2 10.9 1.1 0.3 10.3 0.8 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 SAPS PF04499.10 KEG08158.1 - 0.042 12.5 7.8 0.052 12.1 5.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Daxx PF03344.10 KEG08158.1 - 0.21 10.0 24.5 0.29 9.5 17.0 1.3 1 0 0 1 1 1 0 Daxx Family MIP-T3 PF10243.4 KEG08158.1 - 0.22 9.9 39.3 0.3 9.5 27.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 LSM PF01423.17 KEG08159.1 - 2.1e-10 39.9 0.0 6.5e-10 38.4 0.0 1.7 1 1 0 1 1 1 1 LSM domain Pkinase PF00069.20 KEG08160.1 - 1.5e-73 247.1 0.0 1.7e-73 246.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG08160.1 - 8.4e-32 110.2 0.0 1.2e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEG08160.1 - 0.0012 18.6 0.1 0.18 11.4 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KEG08160.1 - 0.028 13.2 0.0 0.046 12.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 KEG08160.1 - 0.029 13.4 0.1 0.06 12.3 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Motile_Sperm PF00635.21 KEG08161.1 - 0.0047 16.5 0.0 0.017 14.7 0.0 1.8 2 0 0 2 2 2 1 MSP (Major sperm protein) domain Coiled-coil_56 PF09813.4 KEG08162.1 - 0.056 13.4 0.5 0.13 12.2 0.1 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 zf-CCHC_3 PF13917.1 KEG08163.1 - 1.6e-06 27.7 12.6 0.0041 16.8 0.0 3.5 3 0 0 3 3 3 2 Zinc knuckle zf-C4pol PF14260.1 KEG08163.1 - 1.1 9.3 19.4 4.5 7.3 0.8 3.3 3 0 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta TNFR_c6 PF00020.13 KEG08163.1 - 1.9 8.6 20.2 4.9 7.2 0.9 3.4 3 0 0 3 3 3 0 TNFR/NGFR cysteine-rich region RRF PF01765.14 KEG08164.1 - 0.13 11.6 0.9 0.17 11.3 0.6 1.0 1 0 0 1 1 1 0 Ribosome recycling factor DUF1075 PF06388.6 KEG08165.1 - 1.2 8.7 3.4 2 8.0 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1075) DUF2642 PF10842.3 KEG08167.1 - 0.081 12.4 0.1 0.79 9.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2642) TPR_11 PF13414.1 KEG08168.1 - 1.5e-98 322.4 33.7 1.4e-16 59.8 0.2 9.1 5 2 3 9 9 9 9 TPR repeat TPR_1 PF00515.23 KEG08168.1 - 7.6e-90 291.1 31.5 2.1e-08 33.3 0.0 14.1 14 1 0 14 14 14 13 Tetratricopeptide repeat TPR_2 PF07719.12 KEG08168.1 - 4.9e-80 257.1 27.3 1.7e-07 30.6 0.0 14.0 14 0 0 14 14 14 13 Tetratricopeptide repeat TPR_17 PF13431.1 KEG08168.1 - 3.3e-53 173.5 24.9 9.7e-05 22.2 0.0 13.7 15 0 0 15 15 13 8 Tetratricopeptide repeat TPR_16 PF13432.1 KEG08168.1 - 2.6e-43 145.7 31.3 5.1e-07 30.2 0.7 9.6 6 1 1 9 9 9 8 Tetratricopeptide repeat TPR_9 PF13371.1 KEG08168.1 - 3.6e-40 135.6 27.8 0.00021 21.0 0.3 12.4 4 3 9 13 13 13 11 Tetratricopeptide repeat TPR_12 PF13424.1 KEG08168.1 - 5e-39 132.0 34.0 2.9e-10 39.9 0.3 9.5 4 2 6 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.1 KEG08168.1 - 1.1e-37 124.9 17.6 0.0005 19.6 0.0 12.7 10 2 2 12 12 12 9 Tetratricopeptide repeat TPR_14 PF13428.1 KEG08168.1 - 4.6e-25 85.8 19.4 0.0019 18.6 0.0 11.5 5 3 8 13 13 13 5 Tetratricopeptide repeat TPR_6 PF13174.1 KEG08168.1 - 1e-22 78.9 12.3 0.096 13.1 0.0 12.7 13 0 0 13 13 12 4 Tetratricopeptide repeat TPR_7 PF13176.1 KEG08168.1 - 4.6e-20 69.7 24.2 0.06 13.1 0.1 12.7 12 1 1 13 13 12 3 Tetratricopeptide repeat TPR_19 PF14559.1 KEG08168.1 - 8.6e-19 67.6 20.3 0.0023 18.2 0.3 9.5 6 2 4 10 10 10 7 Tetratricopeptide repeat SHNi-TPR PF10516.4 KEG08168.1 - 3e-13 48.7 12.5 0.68 9.2 0.0 10.7 10 1 0 10 10 10 3 SHNi-TPR Apc3 PF12895.2 KEG08168.1 - 4.5e-13 49.1 21.5 0.0003 20.8 1.7 7.9 4 3 3 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.3 KEG08168.1 - 2.8e-09 36.2 14.0 0.0011 17.8 0.1 6.0 4 1 2 7 7 7 3 NMDA receptor-regulated protein 1 BTAD PF03704.12 KEG08168.1 - 7.3e-08 32.8 13.5 0.12 12.7 0.1 6.6 3 1 3 7 7 7 1 Bacterial transcriptional activator domain TPR_15 PF13429.1 KEG08168.1 - 8e-08 31.6 8.5 0.0021 17.2 0.1 7.2 3 2 2 8 8 8 2 Tetratricopeptide repeat FAT PF02259.18 KEG08168.1 - 2.1e-06 26.9 0.9 0.53 9.1 0.1 4.2 3 1 2 5 5 4 2 FAT domain DUF3856 PF12968.2 KEG08168.1 - 4e-05 23.4 6.9 5.1 6.9 0.0 7.5 3 3 5 8 8 8 0 Domain of Unknown Function (DUF3856) Fis1_TPR_C PF14853.1 KEG08168.1 - 5.9e-05 22.8 2.2 1.8 8.4 0.0 6.8 5 2 2 7 7 7 1 Fis1 C-terminal tetratricopeptide repeat TPR_5 PF12688.2 KEG08168.1 - 0.00027 20.9 14.4 0.0069 16.4 0.0 5.3 6 1 1 7 7 6 1 Tetratrico peptide repeat Apc5 PF12862.2 KEG08168.1 - 0.00083 19.1 1.3 6 6.7 0.0 5.1 5 2 0 5 5 5 0 Anaphase-promoting complex subunit 5 MIT PF04212.13 KEG08168.1 - 0.0057 16.4 30.9 9.9 6.1 0.2 9.4 9 1 2 11 11 9 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 KEG08168.1 - 0.014 15.2 22.6 4.1 7.4 0.0 8.8 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_4 PF07721.9 KEG08168.1 - 0.023 15.0 8.6 1.3e+02 3.4 0.0 7.4 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF4435 PF14491.1 KEG08168.1 - 0.054 13.3 0.1 9.3 5.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4435) TPR_20 PF14561.1 KEG08168.1 - 0.11 12.6 15.5 0.17 12.0 0.1 6.3 6 2 2 8 8 7 0 Tetratricopeptide repeat Paf67 PF10255.4 KEG08168.1 - 0.15 10.9 0.5 1.4 7.7 0.0 2.5 2 2 0 2 2 2 0 RNA polymerase I-associated factor PAF67 DUF357 PF04010.8 KEG08168.1 - 0.41 10.3 6.3 6.1 6.6 0.4 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF357) Sec5 PF15469.1 KEG08168.1 - 0.43 10.2 1.9 85 2.8 0.1 3.8 3 1 0 3 3 3 0 Exocyst complex component Sec5 LSM PF01423.17 KEG08169.1 - 4.5e-09 35.7 0.0 6.3e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KEG08169.1 - 0.0061 16.4 0.1 0.031 14.2 0.0 1.9 1 1 1 2 2 2 1 Ataxin 2 SM domain KH_1 PF00013.24 KEG08170.1 - 0.022 14.4 0.1 0.057 13.0 0.1 1.7 1 0 0 1 1 1 0 KH domain Sds3 PF08598.6 KEG08172.1 - 0.15 11.5 0.2 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 Sds3-like Otopetrin PF03189.8 KEG08174.1 - 0.039 12.9 1.1 0.062 12.3 0.8 1.3 1 0 0 1 1 1 0 Otopetrin Med15 PF09606.5 KEG08174.1 - 0.25 9.4 38.0 0.46 8.6 26.4 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Plasmodium_Vir PF05795.6 KEG08174.1 - 0.89 8.6 1.3 1.5 7.9 0.4 1.6 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Zip PF02535.17 KEG08174.1 - 1.6 7.6 17.0 2.8 6.8 11.3 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter Hid1 PF12722.2 KEG08174.1 - 2.5 5.6 11.4 4.5 4.8 7.9 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Raftlin PF15250.1 KEG08174.1 - 5.8 5.3 17.4 0.95 7.9 6.2 2.3 2 0 0 2 2 2 0 Raftlin DUF2870 PF11069.3 KEG08175.1 - 5.3e-27 93.7 0.0 1.3e-26 92.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) SMAP PF15477.1 KEG08176.1 - 2.1e-12 47.1 0.4 2.1e-12 47.1 0.3 1.8 2 0 0 2 2 2 1 Small acidic protein family zf-C3HC4_2 PF13923.1 KEG08180.1 - 1.7e-07 31.1 3.0 1.7e-07 31.1 2.1 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) EF-hand_6 PF13405.1 KEG08180.1 - 6.9e-07 28.6 0.2 0.0024 17.6 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain zf-RING_2 PF13639.1 KEG08180.1 - 1.6e-06 27.7 2.6 1.6e-06 27.7 1.8 2.9 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 KEG08180.1 - 5.3e-06 25.9 3.0 5.3e-06 25.9 2.1 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) EF-hand_1 PF00036.27 KEG08180.1 - 3.1e-05 22.9 0.0 0.022 14.0 0.0 2.5 2 0 0 2 2 2 2 EF hand zf-RING_5 PF14634.1 KEG08180.1 - 6.5e-05 22.5 4.9 6.5e-05 22.5 3.4 2.4 2 0 0 2 2 2 1 zinc-RING finger domain EF-hand_7 PF13499.1 KEG08180.1 - 7.6e-05 22.7 0.7 0.14 12.2 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair zf-C3HC4_4 PF15227.1 KEG08180.1 - 8.9e-05 22.2 2.5 8.9e-05 22.2 1.7 2.9 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 KEG08180.1 - 0.00029 20.5 0.5 0.00099 18.8 0.4 1.9 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 KEG08180.1 - 0.0066 16.1 0.3 0.018 14.7 0.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger DnaJ_CXXCXGXG PF00684.14 KEG08180.1 - 3.6 7.7 12.8 0.03 14.3 2.6 2.2 2 0 0 2 2 1 0 DnaJ central domain zinc-ribbons_6 PF07191.7 KEG08180.1 - 8.8 6.2 10.0 15 5.4 1.2 2.5 2 0 0 2 2 2 0 zinc-ribbons Ank_4 PF13637.1 KEG08183.1 - 3.4e-23 81.5 0.9 2.1e-07 31.2 0.1 5.8 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 KEG08183.1 - 1.1e-20 73.7 0.9 3.3e-10 40.1 0.6 4.0 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KEG08183.1 - 1.6e-20 71.8 7.3 6.6e-06 25.6 0.1 6.2 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 KEG08183.1 - 1.4e-17 63.3 5.5 3.9e-08 33.2 0.4 4.9 4 0 0 4 4 4 3 Ankyrin repeats (many copies) zf-DHHC PF01529.15 KEG08183.1 - 1.9e-13 50.2 0.0 4.3e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 DHHC palmitoyltransferase Ank_3 PF13606.1 KEG08183.1 - 2.4e-10 39.5 10.5 0.023 14.8 0.0 7.1 7 0 0 7 7 7 3 Ankyrin repeat LMBR1 PF04791.11 KEG08185.1 - 2.1 6.8 2.4 3.6 6.0 1.7 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DivIC PF04977.10 KEG08185.1 - 2.9 7.4 12.2 0.78 9.2 2.0 2.8 1 1 0 2 2 2 0 Septum formation initiator HrpA_pilin PF09589.5 KEG08185.1 - 6.7 7.1 13.1 22 5.5 6.0 3.6 2 1 0 2 2 2 0 HrpA pilus formation protein PP2C PF00481.16 KEG08188.1 - 5.1e-55 186.6 0.0 6.2e-55 186.3 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KEG08188.1 - 0.00014 21.3 0.0 0.00033 20.1 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KEG08188.1 - 0.00037 20.2 0.2 0.0021 17.7 0.0 1.9 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) Sec7 PF01369.15 KEG08189.1 - 5.2e-47 159.9 1.2 3e-46 157.5 0.1 2.2 2 0 0 2 2 2 1 Sec7 domain DUF1981 PF09324.5 KEG08189.1 - 2.6e-21 74.9 0.1 9.7e-21 73.0 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1981) Sec7_N PF12783.2 KEG08189.1 - 2.4e-19 69.3 2.2 3.8e-19 68.7 0.4 2.3 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Conotoxin PF02950.12 KEG08190.1 - 0.17 12.7 1.6 0.22 12.3 1.1 1.2 1 0 0 1 1 1 0 Conotoxin NIF PF03031.13 KEG08194.1 - 6.8e-30 103.8 0.0 3e-29 101.7 0.0 1.9 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 KEG08194.1 - 0.12 12.6 0.0 0.37 11.0 0.0 1.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Mito_carr PF00153.22 KEG08195.1 - 7.5e-41 137.7 5.8 6e-14 51.5 0.7 4.0 2 2 1 3 3 3 3 Mitochondrial carrier protein SYCE1 PF15233.1 KEG08196.1 - 0.049 13.5 0.4 0.059 13.3 0.2 1.1 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 Mlp PF03304.8 KEG08196.1 - 0.078 12.9 1.4 0.09 12.7 1.0 1.1 1 0 0 1 1 1 0 Mlp lipoprotein family Borrelia_REV PF03978.8 KEG08196.1 - 0.079 12.6 6.1 0.092 12.4 4.2 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein ubiquitin PF00240.18 KEG08196.1 - 0.22 10.9 2.1 0.23 10.8 0.6 1.7 2 1 0 2 2 2 0 Ubiquitin family Laminin_II PF06009.7 KEG08196.1 - 0.39 10.4 5.0 0.57 9.9 3.5 1.2 1 1 0 1 1 1 0 Laminin Domain II Mucin PF01456.12 KEG08197.1 - 0.01 15.5 1.3 0.013 15.2 0.9 1.4 1 1 0 1 1 1 0 Mucin-like glycoprotein FAM24 PF15193.1 KEG08197.1 - 0.015 15.4 0.2 0.029 14.5 0.1 1.5 1 0 0 1 1 1 0 FAM24 family DREPP PF05558.7 KEG08197.1 - 0.23 11.2 4.9 0.26 11.0 3.4 1.1 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide Mucin PF01456.12 KEG08198.1 - 0.076 12.7 25.9 0.083 12.6 4.9 2.9 3 1 0 3 3 3 0 Mucin-like glycoprotein Syntaxin-6_N PF09177.6 KEG08200.1 - 0.057 13.8 0.8 0.057 13.8 0.5 2.5 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Acetyltransf_1 PF00583.19 KEG08204.1 - 9.7e-14 51.1 0.0 1.7e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEG08204.1 - 4.5e-07 29.9 0.0 7.7e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEG08204.1 - 3.5e-05 23.4 0.0 6.1e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KEG08204.1 - 0.00017 21.6 0.0 0.00035 20.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KEG08204.1 - 0.0016 18.3 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KEG08204.1 - 0.032 14.0 0.0 0.063 13.1 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FlaC_arch PF05377.6 KEG08205.1 - 0.33 10.8 8.0 2.4 8.0 0.1 4.1 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Ribosomal_S19 PF00203.16 KEG08206.1 - 2e-28 97.7 0.2 3.6e-28 96.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S19 PmbA_TldD PF01523.11 KEG08206.1 - 0.0019 17.5 0.0 0.0021 17.3 0.0 1.1 1 0 0 1 1 1 1 Putative modulator of DNA gyrase ATP-gua_PtransN PF02807.10 KEG08206.1 - 0.067 13.3 0.6 0.23 11.6 0.1 2.1 2 1 0 2 2 2 0 ATP:guanido phosphotransferase, N-terminal domain DUF1663 PF07909.6 KEG08207.1 - 1.2e-45 155.9 22.4 2.6e-43 148.2 2.1 2.5 2 1 1 3 3 3 3 Protein of unknown function (DUF1663) Phospholamban PF04272.9 KEG08207.1 - 0.28 10.6 3.6 17 4.9 0.1 3.5 3 0 0 3 3 3 0 Phospholamban DUF912 PF06024.7 KEG08208.1 - 0.47 10.5 2.1 0.98 9.5 1.4 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) H_PPase PF03030.11 KEG08209.1 - 1e-252 840.3 31.5 1e-252 840.3 21.8 1.6 2 0 0 2 2 2 1 Inorganic H+ pyrophosphatase Mito_fiss_reg PF05308.6 KEG08215.1 - 7.1 5.9 8.7 5.9 6.1 0.2 2.7 3 0 0 3 3 3 0 Mitochondrial fission regulator CorA PF01544.13 KEG08216.1 - 3.4e-14 52.5 0.0 1.8e-12 46.9 0.0 2.1 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein CorA PF01544.13 KEG08217.1 - 4.1e-17 62.1 0.0 5.1e-16 58.5 0.0 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein CorA PF01544.13 KEG08218.1 - 4.2e-09 35.8 0.1 5.5e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein AAA PF00004.24 KEG08219.1 - 7.6e-37 126.4 0.0 1.3e-36 125.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KEG08219.1 - 5.7e-05 22.2 0.0 0.00012 21.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KEG08219.1 - 0.00089 18.9 0.0 0.0025 17.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KEG08219.1 - 0.00092 19.3 0.0 0.017 15.2 0.0 2.5 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 KEG08219.1 - 0.0015 17.3 0.0 0.0024 16.6 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 KEG08219.1 - 0.0037 18.0 0.0 0.0072 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEG08219.1 - 0.016 15.2 0.1 0.057 13.3 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.12 KEG08219.1 - 0.022 14.1 0.1 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.1 KEG08219.1 - 0.055 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KEG08219.1 - 0.076 12.1 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KEG08219.1 - 0.085 13.0 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase SOG2 PF10428.4 KEG08219.1 - 4.3 5.8 9.4 6.7 5.2 6.5 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein PQ-loop PF04193.9 KEG08221.1 - 7e-24 83.1 1.2 2.3e-17 62.3 0.0 2.5 2 0 0 2 2 2 2 PQ loop repeat MDMPI_N PF11716.3 KEG08221.1 - 0.093 13.1 0.1 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain SopA_C PF13979.1 KEG08222.1 - 0.11 12.1 0.1 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 SopA-like catalytic domain Pkinase PF00069.20 KEG08223.1 - 9.7e-22 77.3 0.0 2.6e-12 46.4 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEG08223.1 - 3.4e-19 68.9 0.8 7.5e-11 41.5 0.0 3.3 3 1 0 3 3 3 2 Protein tyrosine kinase Mito_carr PF00153.22 KEG08228.1 - 2.3e-24 84.9 0.2 9e-12 44.5 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein NYD-SP28_assoc PF14775.1 KEG08230.1 - 3.3e-25 87.5 2.1 3.3e-24 84.3 0.3 3.5 2 0 0 2 2 2 1 Sperm tail C-terminal domain NYD-SP28 PF14772.1 KEG08230.1 - 1e-21 76.9 10.7 1e-21 76.9 7.4 6.4 4 2 3 7 7 7 1 Sperm tail FTCD_C PF04961.7 KEG08230.1 - 3.5 7.0 8.1 0.59 9.5 0.2 3.4 3 1 1 4 4 4 0 Formiminotransferase-cyclodeaminase FliD_C PF07195.7 KEG08230.1 - 8.4 5.6 24.2 0.11 11.8 2.2 4.0 4 0 0 4 4 4 0 Flagellar hook-associated protein 2 C-terminus SRI PF08236.6 KEG08232.1 - 0.0027 17.5 0.1 0.0058 16.5 0.1 1.5 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain YukC PF10140.4 KEG08232.1 - 0.071 11.6 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC AWPM-19 PF05512.6 KEG08232.1 - 0.15 12.0 0.7 0.23 11.4 0.5 1.2 1 0 0 1 1 1 0 AWPM-19-like family SpoU_methylase PF00588.14 KEG08234.1 - 1.2e-10 41.4 0.1 1.9e-08 34.2 0.0 2.5 2 1 0 2 2 2 2 SpoU rRNA Methylase family TEX13 PF15186.1 KEG08234.1 - 0.033 13.7 1.1 0.49 9.9 0.0 2.3 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family FLgD_tudor PF13861.1 KEG08234.1 - 0.21 11.5 1.6 0.58 10.1 0.0 2.1 2 0 0 2 2 2 0 FlgD Tudor-like domain Cnd2 PF05786.9 KEG08238.1 - 6.6e-11 41.4 0.0 8.1e-11 41.1 0.0 1.2 1 0 0 1 1 1 1 Condensin complex subunit 2 MRC1 PF09444.5 KEG08238.1 - 0.038 14.2 0.8 0.038 14.2 0.6 2.2 2 0 0 2 2 2 0 MRC1-like domain AAA PF00004.24 KEG08239.1 - 1.1e-40 138.9 0.0 2e-40 138.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KEG08239.1 - 2.9e-06 26.4 0.0 1.1e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KEG08239.1 - 3.6e-06 27.1 0.4 8.6e-05 22.6 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KEG08239.1 - 8.4e-05 22.3 0.1 0.00085 19.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Vps4_C PF09336.5 KEG08239.1 - 0.00013 21.7 0.1 0.00029 20.6 0.1 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_17 PF13207.1 KEG08239.1 - 0.00029 21.6 0.6 0.0025 18.6 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEG08239.1 - 0.00068 19.6 0.1 0.0037 17.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 KEG08239.1 - 0.00072 19.2 0.0 0.0021 17.7 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 KEG08239.1 - 0.0013 18.1 0.3 0.049 13.0 0.1 2.8 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.1 KEG08239.1 - 0.0016 18.3 0.0 0.0039 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KEG08239.1 - 0.0017 18.2 0.0 0.0041 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KEG08239.1 - 0.0023 17.1 0.0 0.0043 16.2 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KEG08239.1 - 0.0023 17.3 0.1 0.0061 15.9 0.0 1.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.1 KEG08239.1 - 0.0046 16.5 0.0 0.0082 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KEG08239.1 - 0.0069 15.5 0.0 1.1 8.2 0.0 2.3 1 1 1 2 2 2 1 KaiC TIP49 PF06068.8 KEG08239.1 - 0.0081 14.9 0.0 0.014 14.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus Arch_ATPase PF01637.13 KEG08239.1 - 0.0086 15.8 0.0 0.67 9.5 0.0 2.5 2 0 0 2 2 2 1 Archaeal ATPase NACHT PF05729.7 KEG08239.1 - 0.0098 15.5 0.0 0.055 13.1 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_11 PF13086.1 KEG08239.1 - 0.012 15.2 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KEG08239.1 - 0.013 15.7 0.3 0.054 13.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KEG08239.1 - 0.016 15.3 0.0 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.7 KEG08239.1 - 0.016 14.3 0.0 0.035 13.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 KEG08239.1 - 0.022 14.7 0.0 0.053 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 KEG08239.1 - 0.027 14.3 0.0 0.062 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Parvo_NS1 PF01057.12 KEG08239.1 - 0.059 12.2 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF815 PF05673.8 KEG08239.1 - 0.087 11.7 0.0 0.26 10.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PhoH PF02562.11 KEG08239.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_3 PF07726.6 KEG08239.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KEG08239.1 - 0.15 11.5 0.0 0.53 9.7 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain Baculo_LEF-3 PF05847.6 KEG08240.1 - 0.12 11.2 0.4 0.22 10.4 0.3 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus late expression factor 3 (LEF-3) DUF812 PF05667.6 KEG08241.1 - 6.9e-17 61.1 21.5 9.3e-09 34.3 4.6 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF812) TetR_C_3 PF08362.6 KEG08241.1 - 0.002 17.8 0.1 0.0041 16.8 0.1 1.5 1 0 0 1 1 1 1 YcdC-like protein, C-terminal region AAA_13 PF13166.1 KEG08241.1 - 0.23 9.8 17.4 0.021 13.2 8.0 2.0 1 1 0 1 1 1 0 AAA domain Mnd1 PF03962.10 KEG08241.1 - 0.75 9.4 32.3 0.26 10.9 0.3 3.6 1 1 2 4 4 4 0 Mnd1 family DUF3584 PF12128.3 KEG08241.1 - 2.2 5.4 31.9 3.2 4.9 22.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) BTV_NS2 PF04514.7 KEG08241.1 - 2.3 7.0 13.0 3.7 6.3 9.0 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF1664 PF07889.7 KEG08241.1 - 2.9 7.7 11.1 1.5 8.5 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) APG6 PF04111.7 KEG08241.1 - 7.9 5.4 36.1 0.15 11.0 5.9 3.1 2 1 1 3 3 3 0 Autophagy protein Apg6 Saccharop_dh PF03435.13 KEG08242.1 - 2e-11 43.5 0.0 2.2e-11 43.3 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 KEG08242.1 - 2.3e-06 27.2 0.0 2.8e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEG08242.1 - 0.00022 21.2 0.1 0.00028 20.9 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 KEG08242.1 - 0.0005 20.1 0.0 0.00061 19.8 0.0 1.1 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase KR PF08659.5 KEG08242.1 - 0.0011 18.6 0.1 0.0016 18.1 0.1 1.1 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KEG08242.1 - 0.0018 18.2 0.1 0.0022 17.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 KEG08242.1 - 0.0032 16.7 0.0 0.0043 16.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 KEG08242.1 - 0.0043 15.7 0.0 0.0054 15.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KEG08242.1 - 0.016 15.5 0.0 0.019 15.2 0.0 1.2 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain PUA PF01472.15 KEG08243.1 - 9.1e-16 57.3 0.1 1.7e-15 56.4 0.1 1.5 1 0 0 1 1 1 1 PUA domain QCR10 PF09796.4 KEG08243.1 - 0.65 9.6 0.0 0.65 9.6 0.0 2.4 4 0 0 4 4 4 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) 3-PAP PF12578.3 KEG08244.1 - 3.7e-22 78.7 0.6 3.7e-22 78.7 0.4 3.8 3 1 1 4 4 4 1 Myotubularin-associated protein Dzip-like_N PF13815.1 KEG08244.1 - 3.3e-05 23.6 0.1 3.3e-05 23.6 0.1 4.4 3 2 1 4 4 4 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal VitK2_biosynth PF02621.9 KEG08244.1 - 0.0026 16.9 3.1 0.0031 16.7 0.2 2.2 2 1 0 2 2 2 1 Menaquinone biosynthesis DUF883 PF05957.8 KEG08244.1 - 0.0035 17.7 1.5 0.0035 17.7 1.0 3.5 4 0 0 4 4 4 1 Bacterial protein of unknown function (DUF883) Sina PF03145.11 KEG08244.1 - 0.0058 16.3 1.6 0.015 15.0 1.1 1.6 1 0 0 1 1 1 1 Seven in absentia protein family DM PF00751.13 KEG08244.1 - 0.04 13.4 4.2 0.13 11.8 2.9 2.0 1 0 0 1 1 1 0 DM DNA binding domain DUF2265 PF10023.4 KEG08244.1 - 0.18 10.9 10.7 0.018 14.1 4.0 1.8 2 0 0 2 2 2 0 Predicted aminopeptidase (DUF2265) C1_1 PF00130.17 KEG08244.1 - 0.34 10.6 3.5 0.91 9.3 2.4 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.2 KEG08244.1 - 0.41 10.5 4.4 1.5 8.6 3.0 2.0 1 1 0 1 1 1 0 Double zinc ribbon U1snRNP70_N PF12220.3 KEG08244.1 - 0.49 10.7 8.0 0.098 12.9 1.4 2.9 2 1 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Spectrin PF00435.16 KEG08245.1 - 0.14 12.4 6.9 4.5 7.6 0.0 4.0 4 0 0 4 4 4 0 Spectrin repeat CrtC PF07143.6 KEG08247.1 - 3.5e-09 36.3 0.0 2.4e-06 27.1 0.0 2.5 2 0 0 2 2 2 2 Hydroxyneurosporene synthase (CrtC) ThiF PF00899.16 KEG08248.1 - 6.4e-47 158.7 2.5 3.1e-32 111.2 0.2 2.6 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 KEG08248.1 - 5.5e-28 96.3 0.2 4e-24 83.9 0.1 2.6 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KEG08248.1 - 3e-16 58.5 0.0 5.9e-16 57.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Rhamno_transf PF11316.3 KEG08248.1 - 0.016 14.4 0.1 0.031 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative rhamnosyl transferase NAD_binding_7 PF13241.1 KEG08248.1 - 0.021 15.0 8.5 0.55 10.5 0.1 4.0 3 1 0 3 3 3 0 Putative NAD(P)-binding adh_short PF00106.20 KEG08248.1 - 0.024 14.5 0.2 0.067 13.0 0.2 1.7 1 0 0 1 1 1 0 short chain dehydrogenase TrkA_N PF02254.13 KEG08248.1 - 0.028 14.4 0.1 0.1 12.6 0.1 2.0 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_2 PF07992.9 KEG08248.1 - 0.059 13.2 0.1 0.4 10.5 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 KEG08248.1 - 0.12 11.5 1.7 0.57 9.3 0.0 2.6 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Amnionless PF14828.1 KEG08250.1 - 0.0061 15.1 0.1 0.0077 14.7 0.0 1.0 1 0 0 1 1 1 1 Amnionless Sarcoglycan_2 PF05510.8 KEG08250.1 - 0.0088 14.3 0.1 0.011 14.1 0.1 1.1 1 0 0 1 1 1 1 Sarcoglycan alpha/epsilon Myc_target_1 PF15179.1 KEG08250.1 - 0.01 15.4 0.2 0.015 14.8 0.2 1.3 1 0 0 1 1 1 0 Myc target protein 1 7tm_1 PF00001.16 KEG08250.1 - 0.015 14.4 0.2 0.019 14.1 0.1 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF1049 PF06305.6 KEG08250.1 - 0.046 13.1 0.0 0.079 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) EphA2_TM PF14575.1 KEG08250.1 - 0.047 14.0 0.1 0.075 13.4 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Bap31 PF05529.7 KEG08250.1 - 0.063 12.7 0.7 0.088 12.2 0.5 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Shisa PF13908.1 KEG08250.1 - 0.078 13.1 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Rax2 PF12768.2 KEG08250.1 - 0.086 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Ca_hom_mod PF14798.1 KEG08250.1 - 0.087 11.7 0.2 0.12 11.3 0.1 1.2 1 0 0 1 1 1 0 Calcium homeostasis modulator Tmemb_9 PF05434.6 KEG08250.1 - 0.089 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 TMEM9 Caveolin PF01146.12 KEG08250.1 - 0.092 12.3 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Caveolin SID-1_RNA_chan PF13965.1 KEG08250.1 - 0.098 10.7 0.1 0.11 10.6 0.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TMEM154 PF15102.1 KEG08250.1 - 0.12 12.0 0.7 0.23 11.1 0.4 1.5 1 1 0 1 1 1 0 TMEM154 protein family Chordopox_G3 PF06129.7 KEG08250.1 - 0.13 12.4 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Chordopoxvirus G3 protein Prominin PF05478.6 KEG08250.1 - 0.14 9.6 0.1 0.19 9.2 0.1 1.1 1 0 0 1 1 1 0 Prominin UPF0560 PF10577.4 KEG08250.1 - 0.41 8.8 3.9 0.67 8.1 2.7 1.3 1 1 0 1 1 1 0 Uncharacterised protein family UPF0560 HemY_N PF07219.8 KEG08250.1 - 0.51 9.9 8.1 5.1 6.6 5.6 2.1 1 1 0 1 1 1 0 HemY protein N-terminus LAT PF15234.1 KEG08252.1 - 0.013 14.9 0.0 0.016 14.6 0.0 1.0 1 0 0 1 1 1 0 Linker for activation of T-cells PspB PF06667.7 KEG08252.1 - 0.14 12.1 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Phage shock protein B CcmD PF04995.9 KEG08254.1 - 0.087 12.5 0.8 0.18 11.5 0.6 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) NIF PF03031.13 KEG08256.1 - 3.5e-30 104.7 0.0 5.2e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ClpB_D2-small PF10431.4 KEG08256.1 - 0.13 12.2 0.1 0.41 10.5 0.0 1.8 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein WD40 PF00400.27 KEG08257.1 - 2.1e-15 55.8 3.0 0.00045 19.9 0.0 7.9 9 0 0 9 9 9 3 WD domain, G-beta repeat CENP-F_leu_zip PF10473.4 KEG08257.1 - 0.00057 19.7 9.4 0.00057 19.7 6.5 5.8 3 1 3 6 6 6 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3573 PF12097.3 KEG08257.1 - 0.16 10.5 5.4 0.22 10.0 2.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) Reo_sigmaC PF04582.7 KEG08257.1 - 0.83 8.7 9.4 0.15 11.2 1.9 2.9 2 1 2 4 4 4 0 Reovirus sigma C capsid protein Syja_N PF02383.13 KEG08261.1 - 2.1e-38 131.9 0.0 3.3e-38 131.2 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain DUF2749 PF10907.3 KEG08262.1 - 0.14 12.0 0.1 0.41 10.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) PSP1 PF04468.7 KEG08263.1 - 0.046 13.7 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 PSP1 C-terminal conserved region Tubulin PF00091.20 KEG08264.1 - 1.3e-45 155.8 0.0 1.8e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.1 KEG08264.1 - 0.059 12.2 0.1 0.09 11.7 0.1 1.2 1 0 0 1 1 1 0 Tubulin like zf-CCHC_4 PF14392.1 KEG08270.1 - 0.00067 19.2 3.3 0.29 10.8 0.5 2.8 2 0 0 2 2 2 2 Zinc knuckle eIF3g PF12353.3 KEG08270.1 - 0.58 10.0 4.8 0.82 9.5 0.2 3.0 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G GRAB PF10375.4 KEG08271.1 - 0.00037 20.0 0.1 0.00068 19.2 0.1 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain TMF_TATA_bd PF12325.3 KEG08271.1 - 0.0051 16.5 12.0 0.0051 16.5 8.3 7.7 4 3 3 7 7 7 2 TATA element modulatory factor 1 TATA binding CCDC155 PF14662.1 KEG08271.1 - 0.0054 16.3 25.2 0.0054 16.3 17.4 5.4 3 2 2 5 5 5 1 Coiled-coil region of CCDC155 1-cysPrx_C PF10417.4 KEG08272.1 - 1.4e-14 53.4 0.1 2.4e-14 52.6 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA PF00578.16 KEG08272.1 - 6.2e-12 45.2 0.0 1e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KEG08272.1 - 3.9e-05 23.2 0.0 4.8e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin Rsm1 PF08600.5 KEG08272.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Rsm1-like SKIP_SNW PF02731.10 KEG08273.1 - 4.3e-11 42.5 6.2 4.3e-11 42.5 4.3 3.0 2 1 1 3 3 3 1 SKIP/SNW domain MRP-S31 PF15433.1 KEG08273.1 - 1.4 8.2 13.6 3.2 7.0 9.4 1.5 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Ycf1 PF05758.7 KEG08273.1 - 2.4 5.7 6.3 3.1 5.3 4.2 1.3 2 0 0 2 2 2 0 Ycf1 polyprenyl_synt PF00348.12 KEG08274.1 - 1e-51 175.3 0.2 1.5e-51 174.7 0.2 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase SQS_PSY PF00494.14 KEG08274.1 - 0.00061 19.1 3.4 0.001 18.4 2.3 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase ELFV_dehydrog PF00208.16 KEG08275.1 - 1.3e-48 165.7 0.0 2.2e-48 164.9 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 KEG08275.1 - 9.3e-18 63.1 0.2 5.5e-09 34.0 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 KEG08275.1 - 0.0051 16.3 0.0 0.053 13.1 0.0 2.6 3 0 0 3 3 3 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain SET PF00856.23 KEG08286.1 - 3.4e-14 53.4 0.1 3.3e-13 50.2 0.1 2.1 1 1 0 1 1 1 1 SET domain DUF4620 PF15399.1 KEG08286.1 - 0.046 13.8 0.5 0.12 12.5 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4620) Ank_2 PF12796.2 KEG08286.1 - 0.1 12.9 0.0 0.29 11.5 0.0 1.8 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) zf-C3HC4_3 PF13920.1 KEG08286.1 - 0.99 9.1 17.2 0.071 12.7 1.8 4.0 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) DNA_pol_B_palm PF14792.1 KEG08288.1 - 7.2e-20 71.1 0.0 1.6e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 KEG08288.1 - 9.1e-20 70.1 0.1 4.5e-11 42.2 0.0 2.5 2 0 0 2 2 2 2 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 KEG08288.1 - 9.6e-16 57.0 0.0 5.2e-15 54.7 0.0 2.2 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 KEG08288.1 - 4.4e-15 55.6 0.2 4e-13 49.3 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_5 PF14520.1 KEG08288.1 - 0.00022 21.3 0.1 0.13 12.4 0.0 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix domain RNA_pol_A_CTD PF03118.10 KEG08288.1 - 0.0076 15.6 0.1 5.9 6.3 0.0 2.9 1 1 2 3 3 3 2 Bacterial RNA polymerase, alpha chain C terminal domain IMS_HHH PF11798.3 KEG08288.1 - 0.0085 16.0 0.0 2 8.6 0.0 2.6 2 0 0 2 2 2 1 IMS family HHH motif HHH_3 PF12836.2 KEG08288.1 - 0.021 14.7 0.2 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif EMP70 PF02990.11 KEG08290.1 - 4.5e-147 490.6 13.2 5.8e-147 490.3 9.1 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Kinesin PF00225.18 KEG08291.1 - 6.8e-84 281.4 0.0 8.9e-84 281.0 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain AAA_16 PF13191.1 KEG08291.1 - 0.0082 16.1 0.1 0.035 14.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain bZIP_2 PF07716.10 KEG08291.1 - 0.023 14.4 3.8 0.065 13.0 0.3 2.8 2 0 0 2 2 2 0 Basic region leucine zipper AAA_22 PF13401.1 KEG08291.1 - 0.056 13.5 0.0 0.65 10.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain TSC22 PF01166.13 KEG08291.1 - 0.075 13.0 1.6 0.24 11.3 1.1 1.9 1 0 0 1 1 1 0 TSC-22/dip/bun family HALZ PF02183.13 KEG08291.1 - 0.69 9.6 5.8 1 9.1 0.3 3.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper bZIP_1 PF00170.16 KEG08291.1 - 2.2 8.2 8.0 0.11 12.4 0.2 2.8 3 0 0 3 3 3 0 bZIP transcription factor Shugoshin_N PF07558.6 KEG08291.1 - 2.7 7.7 6.9 0.15 11.8 0.2 2.3 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region DUF904 PF06005.7 KEG08291.1 - 3.3 8.0 12.8 11 6.3 2.4 3.5 2 1 0 2 2 2 0 Protein of unknown function (DUF904) AAA_23 PF13476.1 KEG08291.1 - 8 6.7 8.1 7.7 6.7 0.0 3.0 2 1 0 2 2 2 0 AAA domain Ku PF02735.11 KEG08292.1 - 1.9e-15 56.7 0.0 3.7e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 KEG08292.1 - 9.2e-06 25.2 0.0 1.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain MAGE_N PF12440.3 KEG08294.1 - 1.4 9.2 8.5 5.4 7.3 5.1 2.4 1 1 1 2 2 2 0 Melanoma associated antigen family N terminal ABC1 PF03109.11 KEG08297.1 - 1.4e-29 102.4 0.1 5.9e-18 64.9 0.0 2.4 2 0 0 2 2 2 2 ABC1 family PSP1 PF04468.7 KEG08298.1 - 1.3e-31 108.4 0.7 3.6e-31 106.9 0.5 1.8 1 0 0 1 1 1 1 PSP1 C-terminal conserved region CEP44 PF15007.1 KEG08301.1 - 6.7e-07 29.0 0.0 1.1e-06 28.3 0.0 1.3 1 1 0 1 1 1 1 Centrosomal spindle body, CEP44 YuzL PF14115.1 KEG08304.1 - 0.012 15.9 1.2 0.037 14.3 0.5 2.0 1 1 1 2 2 2 0 YuzL-like protein Pro_isomerase PF00160.16 KEG08305.1 - 1.5e-44 151.9 0.0 1.9e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GlutR_dimer PF00745.15 KEG08307.1 - 0.038 13.9 1.1 3.6 7.5 0.0 2.3 2 1 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF4206 PF13901.1 KEG08308.1 - 8.1e-20 71.2 15.9 9.5e-15 54.6 1.7 3.3 3 0 0 3 3 3 3 Domain of unknown function (DUF4206) zf-LSD1 PF06943.7 KEG08309.1 - 1.8e-08 33.8 8.6 1.8e-08 33.8 5.9 2.7 3 0 0 3 3 3 1 LSD1 zinc finger FLO_LFY PF01698.11 KEG08309.1 - 0.1 11.4 0.2 0.12 11.1 0.2 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein ELO PF01151.13 KEG08310.1 - 2.5e-21 76.1 12.7 3.2e-21 75.7 8.8 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF4661 PF15576.1 KEG08310.1 - 0.058 13.0 0.5 0.094 12.3 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) ELO PF01151.13 KEG08311.1 - 3.1e-74 249.4 9.7 3.6e-74 249.2 6.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Vma12 PF11712.3 KEG08311.1 - 0.097 12.3 0.8 2.5 7.7 0.3 2.4 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Kinesin PF00225.18 KEG08312.1 - 2.7e-91 305.7 0.1 1.2e-90 303.6 0.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain DUF4533 PF15047.1 KEG08312.1 - 0.018 14.4 0.4 0.044 13.1 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4533) DUF4201 PF13870.1 KEG08313.1 - 5e-41 140.0 15.4 5e-41 140.0 10.7 3.1 2 1 0 3 3 3 2 Domain of unknown function (DUF4201) DUF948 PF06103.6 KEG08313.1 - 0.029 14.2 2.5 1.2 9.0 0.2 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Snapin_Pallidin PF14712.1 KEG08313.1 - 0.12 12.7 0.3 0.12 12.7 0.2 4.0 4 1 1 5 5 5 0 Snapin/Pallidin TMF_DNA_bd PF12329.3 KEG08313.1 - 8.6 6.2 17.3 5.6 6.8 0.0 4.6 4 1 1 5 5 5 0 TATA element modulatory factor 1 DNA binding Pkinase PF00069.20 KEG08314.1 - 8.3e-34 116.9 0.0 1.4e-27 96.5 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEG08314.1 - 2.9e-06 26.5 0.0 4.6e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEG08314.1 - 0.0015 18.2 0.0 0.0034 17.1 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family UPF0444 PF15475.1 KEG08314.1 - 0.022 14.7 1.6 0.022 14.7 1.1 2.0 2 0 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 DEAD PF00270.24 KEG08316.1 - 1.5e-33 115.6 0.0 1.1e-32 112.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEG08316.1 - 4.3e-27 93.7 0.0 1.2e-26 92.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 KEG08316.1 - 0.0068 14.8 0.6 0.014 13.8 0.1 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF1253) Lipase_GDSL_2 PF13472.1 KEG08316.1 - 0.084 12.9 0.0 0.39 10.8 0.0 2.1 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family ResIII PF04851.10 KEG08316.1 - 0.092 12.5 0.0 0.75 9.5 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DnaJ PF00226.26 KEG08317.1 - 4.7e-12 45.4 0.0 1.1e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain U-box PF04564.10 KEG08318.1 - 7.3e-09 35.4 0.5 4.7e-08 32.8 0.0 2.5 3 0 0 3 3 3 1 U-box domain Rtf2 PF04641.7 KEG08318.1 - 5.9e-06 25.6 0.0 1.1e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 KEG08318.1 - 2.4e-05 23.7 0.1 0.0001 21.7 0.1 2.0 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit FGGY_N PF00370.16 KEG08319.1 - 2.6e-64 216.9 0.0 3.5e-64 216.4 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 KEG08319.1 - 3.1e-59 199.9 0.9 5e-59 199.2 0.6 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain zf-TFIIB PF13453.1 KEG08320.1 - 0.26 10.5 2.8 0.35 10.1 1.0 1.8 2 0 0 2 2 2 0 Transcription factor zinc-finger Endonuclease_7 PF02945.10 KEG08320.1 - 7.9 6.2 11.9 2.3 7.9 6.5 1.5 2 0 0 2 2 2 0 Recombination endonuclease VII EF-hand_7 PF13499.1 KEG08321.1 - 3.3e-11 43.1 2.0 8.9e-08 32.1 0.1 4.7 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_8 PF13833.1 KEG08321.1 - 9.6e-06 25.1 3.1 0.036 13.6 0.1 4.0 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.1 KEG08321.1 - 1e-05 24.9 0.8 0.071 13.0 0.1 5.5 5 1 1 6 6 6 1 EF-hand domain EF-hand_1 PF00036.27 KEG08321.1 - 1.3e-05 24.0 4.8 0.013 14.7 0.0 4.9 6 0 0 6 6 6 2 EF hand EF-hand_5 PF13202.1 KEG08321.1 - 0.00059 19.0 1.1 0.0038 16.5 0.0 2.9 3 0 0 3 3 3 1 EF hand Thioredoxin PF00085.15 KEG08322.1 - 5.6e-10 38.8 0.0 8.2e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 KEG08322.1 - 0.0065 16.0 0.1 0.01 15.3 0.1 1.4 1 1 0 1 1 1 1 Redoxin Cys_Met_Meta_PP PF01053.15 KEG08323.1 - 2.7e-125 417.6 0.2 3.1e-125 417.4 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KEG08323.1 - 2.2e-11 43.3 2.8 4.9e-11 42.2 1.9 1.6 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 KEG08323.1 - 3.9e-08 32.6 0.1 5.3e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KEG08323.1 - 2.2e-06 26.7 0.0 4e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KEG08323.1 - 3.5e-06 26.3 0.2 5.7e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Rab5-bind PF09311.6 KEG08324.1 - 0.011 15.6 16.5 0.02 14.8 11.4 1.3 1 0 0 1 1 1 0 Rabaptin-like protein Cast PF10174.4 KEG08324.1 - 0.03 12.3 14.0 0.064 11.2 9.5 1.5 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone HALZ PF02183.13 KEG08324.1 - 0.068 12.9 0.6 0.068 12.9 0.4 3.1 4 0 0 4 4 4 0 Homeobox associated leucine zipper GAS PF13851.1 KEG08324.1 - 0.1 11.7 10.7 0.067 12.3 5.1 1.9 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.6 KEG08324.1 - 0.11 11.0 3.8 0.18 10.4 2.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF972 PF06156.8 KEG08324.1 - 1.5 9.2 11.1 0.81 10.0 4.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Myc-LZ PF02344.10 KEG08324.1 - 1.7 8.3 6.9 0.47 10.1 1.6 2.4 2 0 0 2 2 2 0 Myc leucine zipper domain APG6 PF04111.7 KEG08324.1 - 1.9 7.4 8.7 3.5 6.6 6.0 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 YlqD PF11068.3 KEG08324.1 - 2.8 8.0 11.0 1.7 8.7 5.9 1.8 2 0 0 2 2 2 0 YlqD protein Fez1 PF06818.10 KEG08324.1 - 3.1 7.7 15.2 2.1 8.2 9.5 1.4 2 0 0 2 2 2 0 Fez1 DUF904 PF06005.7 KEG08324.1 - 4 7.7 10.0 1.3 9.3 4.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF904) FUSC PF04632.7 KEG08324.1 - 8.4 4.6 16.0 11 4.3 11.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Spc24 PF08286.6 KEG08324.1 - 8.7 6.0 9.1 49 3.6 4.4 2.8 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 ADIP PF11559.3 KEG08324.1 - 9 6.1 13.7 2.9 7.7 6.7 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Peptidase_M8 PF01457.11 KEG08325.1 - 9.9e-39 133.0 0.1 1.2e-38 132.8 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin Zip PF02535.17 KEG08327.1 - 0.0066 15.4 2.5 0.0073 15.3 1.7 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter PQ-loop PF04193.9 KEG08328.1 - 1.2e-32 111.2 17.8 7.3e-17 60.6 1.7 3.3 3 0 0 3 3 3 2 PQ loop repeat DUF2721 PF11026.3 KEG08328.1 - 0.5 9.9 5.4 5.8 6.5 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) Zip PF02535.17 KEG08330.1 - 3.1e-29 101.9 10.8 3.6e-29 101.7 7.5 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter PQ-loop PF04193.9 KEG08331.1 - 9.5e-31 105.1 13.5 1.7e-16 59.4 1.7 3.3 4 0 0 4 4 4 2 PQ loop repeat DUF2721 PF11026.3 KEG08331.1 - 3.8 7.1 8.9 6 6.5 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) NTP_transf_3 PF12804.2 KEG08333.1 - 1.2e-05 25.4 0.2 0.00053 20.0 0.1 2.7 2 0 0 2 2 2 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 KEG08333.1 - 0.00056 19.2 0.1 0.0011 18.3 0.1 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase Nucleoplasmin PF03066.10 KEG08333.1 - 0.0037 16.8 1.2 0.091 12.2 0.3 2.5 2 0 0 2 2 2 1 Nucleoplasmin Hexapep PF00132.19 KEG08333.1 - 0.0057 16.1 16.8 0.1 12.1 2.3 4.1 1 1 4 5 5 5 5 Bacterial transferase hexapeptide (six repeats) PBP1_TM PF14812.1 KEG08333.1 - 1.4 9.2 13.1 2.1 8.7 4.6 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Hom_end_hint PF05203.11 KEG08334.1 - 0.13 11.9 0.8 0.15 11.7 0.6 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint HALZ PF02183.13 KEG08334.1 - 1.8 8.3 12.4 0.29 10.8 1.4 3.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper Atg14 PF10186.4 KEG08334.1 - 2.9 6.7 25.7 4 6.2 17.8 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Cep57_MT_bd PF06657.8 KEG08335.1 - 0.0056 16.5 0.9 0.0092 15.9 0.3 1.7 1 1 0 1 1 1 1 Centrosome microtubule-binding domain of Cep57 Zwint PF15556.1 KEG08335.1 - 0.013 14.8 0.9 0.015 14.5 0.7 1.1 1 0 0 1 1 1 0 ZW10 interactor Sec8_exocyst PF04048.9 KEG08335.1 - 0.048 13.2 0.2 0.052 13.1 0.1 1.2 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain eIF3_N PF09440.5 KEG08336.1 - 7.1e-20 71.5 0.0 2.3e-19 69.8 0.0 1.9 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 KEG08336.1 - 4.6e-09 36.5 0.0 9.8e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 PCI domain Med15 PF09606.5 KEG08337.1 - 3.5e-06 25.5 31.2 4.1e-06 25.3 21.6 1.3 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Utp14 PF04615.8 KEG08337.1 - 0.0017 16.6 21.4 0.0023 16.2 14.8 1.2 1 0 0 1 1 1 1 Utp14 protein AAA_22 PF13401.1 KEG08337.1 - 0.033 14.3 3.0 0.078 13.1 2.0 1.6 1 1 0 1 1 1 0 AAA domain SAPS PF04499.10 KEG08337.1 - 0.13 10.8 11.8 0.0088 14.7 2.2 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Suf PF05843.9 KEG08337.1 - 0.3 10.7 23.4 0.62 9.7 16.2 1.6 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) Pex14_N PF04695.8 KEG08337.1 - 0.47 10.5 19.7 3.3 7.7 11.3 2.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region BAF1_ABF1 PF04684.8 KEG08337.1 - 0.58 8.9 25.8 0.018 13.8 13.3 1.8 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Peptidase_S64 PF08192.6 KEG08337.1 - 4 5.6 11.4 4.7 5.4 7.9 1.3 1 0 0 1 1 1 0 Peptidase family S64 IncA PF04156.9 KEG08337.1 - 5 6.6 24.9 1 8.9 10.9 2.4 2 0 0 2 2 2 0 IncA protein Ycf1 PF05758.7 KEG08337.1 - 6.3 4.3 14.7 0.11 10.2 4.5 1.8 2 0 0 2 2 2 0 Ycf1 Dicty_REP PF05086.7 KEG08337.1 - 8.4 4.0 6.8 14 3.2 4.7 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF2052 PF09747.4 KEG08337.1 - 9.5 6.1 30.7 0.97 9.3 9.8 2.6 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) Glyco_hydro_32N PF00251.15 KEG08339.1 - 2.6e-27 95.9 1.4 3.7e-27 95.5 0.5 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 KEG08339.1 - 0.0097 16.2 0.0 0.032 14.6 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal PAN_4 PF14295.1 KEG08339.1 - 0.019 14.6 0.2 0.048 13.3 0.2 1.6 1 0 0 1 1 1 0 PAN domain DUF2500 PF10694.4 KEG08341.1 - 0.0045 16.9 0.0 0.0092 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2500) Mic1 PF07035.7 KEG08342.1 - 0.00054 19.3 0.1 0.00091 18.6 0.0 1.3 1 0 0 1 1 1 1 Colon cancer-associated protein Mic1-like DnaJ PF00226.26 KEG08343.1 - 1.1e-10 41.1 0.0 2.1e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain FliD_N PF02465.13 KEG08344.1 - 0.23 11.8 1.8 0.5 10.7 1.2 1.5 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Skp1 PF01466.14 KEG08348.1 - 4.4e-05 23.4 0.8 0.00019 21.3 0.6 1.8 1 1 0 1 1 1 1 Skp1 family, dimerisation domain Skp1 PF01466.14 KEG08349.1 - 0.00015 21.7 0.2 0.00079 19.4 0.1 2.1 1 1 0 1 1 1 1 Skp1 family, dimerisation domain IRK PF01007.15 KEG08352.1 - 0.00018 20.4 5.4 0.084 11.6 0.0 3.2 3 1 0 3 3 3 2 Inward rectifier potassium channel DHHA1 PF02272.14 KEG08352.1 - 0.64 9.7 5.5 1.4 8.6 3.8 1.6 1 0 0 1 1 1 0 DHHA1 domain Metallophos PF00149.23 KEG08353.1 - 2.3e-28 98.9 0.1 3.3e-28 98.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KEG08353.1 - 0.014 15.2 0.0 0.053 13.3 0.0 1.9 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain PBP1_TM PF14812.1 KEG08354.1 - 4.7 7.5 6.0 11 6.4 4.2 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MSP1_C PF07462.6 KEG08355.1 - 0.092 11.1 0.9 0.14 10.4 0.6 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Mcm10 PF09332.6 KEG08355.1 - 0.58 9.4 6.1 2.2 7.5 2.6 2.2 2 0 0 2 2 2 0 Mcm10 replication factor TauE PF01925.14 KEG08356.1 - 0.1 11.9 4.0 0.15 11.5 2.8 1.1 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE RDD PF06271.7 KEG08356.1 - 0.71 9.7 4.2 1.2 9.0 2.9 1.4 1 1 0 1 1 1 0 RDD family TruD PF01142.13 KEG08357.1 - 0.055 12.1 0.0 1.1 7.8 0.0 2.9 2 1 0 2 2 2 0 tRNA pseudouridine synthase D (TruD) zf-HC5HC2H PF13771.1 KEG08358.1 - 6e-05 23.1 10.4 6e-05 23.1 7.2 2.3 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 KEG08358.1 - 0.092 12.7 14.4 0.024 14.6 5.5 2.4 2 0 0 2 2 2 0 PHD-zinc-finger like domain NIF PF03031.13 KEG08359.1 - 1.1e-29 103.0 0.2 1.7e-29 102.5 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase EF-hand_9 PF14658.1 KEG08360.1 - 2.8e-10 39.9 0.2 1.6e-06 27.9 0.0 2.9 2 1 1 3 3 3 2 EF-hand domain EF-hand_6 PF13405.1 KEG08360.1 - 3.9e-05 23.1 0.0 1.1 9.3 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 KEG08360.1 - 5.9e-05 23.1 0.2 0.27 11.4 0.0 2.8 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 KEG08360.1 - 0.019 14.2 0.0 9.7 5.7 0.0 3.4 3 0 0 3 3 3 0 EF hand EF-hand_8 PF13833.1 KEG08360.1 - 0.035 13.7 0.9 0.092 12.3 0.0 2.1 3 0 0 3 3 3 0 EF-hand domain pair IQ PF00612.22 KEG08361.1 - 9.1e-31 102.5 185.2 2.9e-05 23.3 1.1 25.8 26 1 1 27 27 27 18 IQ calmodulin-binding motif TPR_12 PF13424.1 KEG08361.1 - 8.2e-13 48.1 9.6 2.8e-09 36.7 0.2 4.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 KEG08361.1 - 1.4e-11 43.8 3.1 1.4e-06 27.8 0.1 4.8 4 0 0 4 4 4 2 TPR repeat TPR_10 PF13374.1 KEG08361.1 - 0.00011 22.0 0.2 0.00011 22.0 0.2 7.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEG08361.1 - 0.00017 21.0 6.8 0.022 14.3 0.0 5.3 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEG08361.1 - 0.00089 18.9 11.5 0.25 11.3 0.1 5.9 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEG08361.1 - 0.58 10.0 6.3 0.19 11.5 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Tau95 PF09734.4 KEG08362.1 - 1.3e-55 188.9 0.0 1.7e-55 188.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit zf-LSD1 PF06943.7 KEG08364.1 - 0.64 9.6 5.9 6 6.5 0.2 2.7 2 0 0 2 2 2 0 LSD1 zinc finger Glyco_hydro_85 PF03644.8 KEG08367.1 - 5.5e-89 298.3 0.0 7.6e-89 297.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Peptidase_C97 PF05903.9 KEG08367.1 - 4.1e-23 81.8 0.0 6.8e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUB PF09409.5 KEG08367.1 - 5.7e-15 54.8 0.0 1e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 PUB domain Hid1 PF12722.2 KEG08369.1 - 2.9 5.4 9.6 3.7 5.1 6.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Avl9 PF09794.4 KEG08370.1 - 6.6e-05 21.5 0.1 0.00044 18.8 0.0 2.0 2 0 0 2 2 2 1 Transport protein Avl9 SPA PF08616.5 KEG08370.1 - 0.0086 15.7 0.2 0.039 13.6 0.1 2.1 1 1 1 2 2 2 1 Stabilization of polarity axis DENN PF02141.16 KEG08370.1 - 0.029 14.1 6.9 15 5.2 4.8 3.0 1 1 0 1 1 1 0 DENN (AEX-3) domain Afi1 PF07792.7 KEG08370.1 - 0.035 14.1 0.0 0.075 13.0 0.0 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Acetyltransf_10 PF13673.1 KEG08371.1 - 0.00091 19.3 0.0 0.0021 18.1 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KEG08371.1 - 0.0033 17.4 0.0 0.0071 16.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KEG08371.1 - 0.018 15.0 0.3 0.044 13.7 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DnaJ PF00226.26 KEG08372.1 - 9.8e-21 73.2 0.3 1.8e-20 72.4 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 KEG08372.1 - 0.03 14.5 0.2 0.067 13.4 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1977) PAP1 PF08601.5 KEG08373.1 - 0.49 10.0 6.3 0.67 9.5 4.4 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 DUF1180 PF06679.7 KEG08373.1 - 5.2 6.9 7.0 1.7 8.4 2.4 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) PglZ PF08665.7 KEG08374.1 - 0.13 11.9 0.1 0.68 9.5 0.0 2.1 2 1 1 3 3 3 0 PglZ domain CTDII PF01556.13 KEG08376.1 - 1.8e-21 75.8 0.2 4e-20 71.4 0.0 2.8 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ PF00226.26 KEG08376.1 - 8.4e-18 63.8 0.5 1.8e-17 62.8 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KEG08376.1 - 2.8e-14 52.9 16.5 4.6e-14 52.1 11.4 1.4 1 0 0 1 1 1 1 DnaJ central domain DUF4248 PF14053.1 KEG08376.1 - 0.062 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) HypA PF01155.14 KEG08376.1 - 0.81 9.4 10.5 1.6 8.4 1.2 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 KEG08376.1 - 1.4 8.8 13.7 15 5.5 1.4 2.2 1 1 1 2 2 2 0 Double zinc ribbon A2L_zn_ribbon PF08792.5 KEG08376.1 - 1.7 8.1 9.7 20 4.7 0.1 3.4 2 1 1 3 3 3 0 A2L zinc ribbon domain Pyr_redox_2 PF07992.9 KEG08377.1 - 1.4e-43 149.1 2.0 1.4e-43 149.1 1.4 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KEG08377.1 - 1.1e-38 131.6 0.7 3.7e-38 129.9 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 KEG08377.1 - 1.6e-20 73.3 5.7 3.2e-17 62.7 0.3 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KEG08377.1 - 4.2e-11 42.5 0.7 4.2e-11 42.5 0.5 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEG08377.1 - 6.1e-11 42.7 0.2 2.1e-07 31.2 0.1 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KEG08377.1 - 1.1e-08 34.4 12.8 6.5e-07 28.5 5.1 3.0 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KEG08377.1 - 1.5e-08 33.9 11.3 8.4e-08 31.4 2.0 3.3 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.1 KEG08377.1 - 7.2e-07 29.1 6.2 0.00013 21.8 0.6 2.9 3 0 0 3 3 2 2 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KEG08377.1 - 7.6e-06 25.1 1.2 9e-05 21.6 0.1 2.5 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 KEG08377.1 - 0.00013 20.5 1.2 0.00013 20.5 0.8 4.1 4 1 1 5 5 5 1 HI0933-like protein FAD_binding_3 PF01494.14 KEG08377.1 - 0.00015 20.9 12.9 0.021 13.8 0.6 3.2 2 1 1 3 3 3 3 FAD binding domain AlaDh_PNT_C PF01262.16 KEG08377.1 - 0.00018 21.1 3.0 0.04 13.4 0.1 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.1 KEG08377.1 - 0.0002 20.3 0.2 0.11 11.3 0.0 2.6 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.13 KEG08377.1 - 0.0018 17.9 2.4 0.0091 15.6 0.1 2.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.19 KEG08377.1 - 0.0048 15.8 19.6 0.007 15.3 1.7 3.5 2 2 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 KEG08377.1 - 0.044 14.0 3.3 0.98 9.7 0.1 2.7 3 0 0 3 3 2 0 Putative NAD(P)-binding TrkA_N PF02254.13 KEG08377.1 - 0.071 13.1 0.5 0.25 11.3 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain Lycopene_cycl PF05834.7 KEG08377.1 - 0.56 9.0 6.9 0.48 9.2 0.4 2.5 2 1 1 3 3 3 0 Lycopene cyclase protein Cyclin_N PF00134.18 KEG08378.1 - 5e-38 129.5 0.4 1.7e-37 127.8 0.1 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KEG08378.1 - 3.3e-31 107.6 0.2 8.9e-31 106.2 0.1 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain EF-hand_1 PF00036.27 KEG08379.1 - 2.7e-15 54.4 3.8 2.4e-06 26.4 0.0 5.0 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.1 KEG08379.1 - 2.9e-15 54.6 7.5 5.5e-05 22.7 0.1 4.2 4 1 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 KEG08379.1 - 4e-15 55.6 0.8 1e-07 31.9 0.2 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 KEG08379.1 - 2.6e-10 39.1 0.8 5e-05 22.4 0.0 5.1 5 1 0 5 5 5 2 EF hand EF-hand_8 PF13833.1 KEG08379.1 - 3e-10 39.5 8.6 0.0001 21.8 0.6 4.0 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_10 PF14788.1 KEG08379.1 - 0.0026 17.3 0.9 2.7 7.7 0.1 3.3 3 0 0 3 3 3 1 EF hand SPARC_Ca_bdg PF10591.4 KEG08379.1 - 0.022 14.7 0.9 0.078 13.0 0.2 2.1 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Aa_trans PF01490.13 KEG08381.1 - 9.7e-46 156.0 36.7 1.8e-45 155.1 25.4 1.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Bacteriocin_IIc PF10439.4 KEG08381.1 - 1.9 8.6 5.2 1.5 9.0 0.5 2.4 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Lipase_3 PF01764.20 KEG08384.1 - 1.6e-25 89.3 0.0 2.3e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 KEG08384.1 - 0.0028 17.5 0.1 0.0037 17.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KEG08384.1 - 0.0029 17.8 0.2 0.0052 17.0 0.1 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.2 KEG08384.1 - 0.0032 17.2 0.0 0.004 16.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 KEG08384.1 - 0.012 14.9 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF2048 PF09752.4 KEG08384.1 - 0.012 14.4 0.2 0.019 13.8 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Esterase PF00756.15 KEG08384.1 - 0.33 10.3 3.4 0.56 9.5 2.3 1.6 1 1 0 1 1 1 0 Putative esterase Lipase_3 PF01764.20 KEG08385.1 - 2.2e-10 40.2 0.0 3.4e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Peptidase_M8 PF01457.11 KEG08386.1 - 1.3e-133 446.1 0.0 1.5e-133 445.8 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin Astacin PF01400.19 KEG08386.1 - 0.013 14.9 0.2 0.023 14.0 0.1 1.4 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.19 KEG08386.1 - 0.065 12.9 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 Matrixin Peptidase_M57 PF12388.3 KEG08386.1 - 0.1 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Inhibitor_Mig-6 PF11555.3 KEG08387.1 - 0.18 12.2 2.4 0.23 11.8 1.6 1.3 1 1 0 1 1 1 0 EGFR receptor inhibitor Mig-6 BatA PF07584.6 KEG08388.1 - 0.0071 16.5 0.1 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 Aerotolerance regulator N-terminal YqgF PF14639.1 KEG08389.1 - 6.3e-14 51.7 0.0 3e-13 49.5 0.0 2.2 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SH2_2 PF14633.1 KEG08389.1 - 2.5e-08 33.2 0.0 4.5e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 SH2 domain BAF1_ABF1 PF04684.8 KEG08389.1 - 0.13 11.0 7.6 0.12 11.2 1.5 2.3 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Cuticle_2 PF08184.6 KEG08389.1 - 0.82 9.5 4.3 32 4.3 0.0 3.7 4 0 0 4 4 4 0 Cuticle protein 7 isoform family FBPase PF00316.15 KEG08390.1 - 8.6e-36 123.3 0.0 9.8e-36 123.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase PqiA PF04403.8 KEG08391.1 - 1.5e-14 53.9 8.2 1.5e-14 53.9 5.7 3.7 2 1 1 3 3 3 1 Paraquat-inducible protein A LBP_BPI_CETP PF01273.20 KEG08391.1 - 0.00084 18.7 0.8 0.0028 17.0 0.5 1.9 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain RRM_1 PF00076.17 KEG08392.1 - 1.7e-59 197.3 0.0 1.1e-19 69.8 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG08392.1 - 1.9e-42 143.1 0.0 4e-12 45.9 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG08392.1 - 3.4e-31 106.8 0.0 9.9e-11 41.3 0.0 5.0 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 KEG08392.1 - 1.9e-22 78.7 0.8 6.8e-22 76.9 0.6 2.0 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 KEG08392.1 - 8.2e-07 28.6 0.0 5.5 6.8 0.0 4.6 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KEG08392.1 - 8.6e-07 28.7 0.4 0.48 10.3 0.0 4.3 3 1 1 4 4 4 2 RNA binding motif DUF382 PF04037.8 KEG08392.1 - 0.11 12.3 1.6 0.25 11.1 1.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF382) DUF605 PF04652.11 KEG08392.1 - 6.9 5.9 12.5 10 5.4 8.6 1.2 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 KEG08392.1 - 8.4 4.4 23.4 11 4.0 16.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Snf7 PF03357.16 KEG08394.1 - 0.068 12.5 0.5 0.09 12.1 0.3 1.1 1 0 0 1 1 1 0 Snf7 Peptidase_M8 PF01457.11 KEG08395.1 - 2.1e-137 458.6 3.7 2.5e-137 458.3 2.5 1.0 1 0 0 1 1 1 1 Leishmanolysin Astacin PF01400.19 KEG08395.1 - 0.032 13.6 0.0 0.065 12.6 0.0 1.4 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) AAA PF00004.24 KEG08398.1 - 1.2e-34 119.3 0.0 3.9e-31 107.9 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KEG08398.1 - 7.8e-11 41.6 0.0 0.00019 20.9 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_22 PF13401.1 KEG08398.1 - 9.2e-11 42.0 0.1 0.00019 21.5 0.1 3.8 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KEG08398.1 - 3.2e-10 40.0 0.2 4.9e-06 26.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KEG08398.1 - 1.2e-08 35.2 5.3 0.0042 17.0 0.0 3.9 3 1 1 4 4 3 2 AAA ATPase domain Zeta_toxin PF06414.7 KEG08398.1 - 5.5e-08 32.1 0.0 0.011 14.8 0.0 3.0 3 0 0 3 3 3 2 Zeta toxin AAA_5 PF07728.9 KEG08398.1 - 2.3e-07 30.6 0.1 0.00076 19.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KEG08398.1 - 3.9e-07 30.9 0.0 0.00012 22.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain DUF815 PF05673.8 KEG08398.1 - 1.2e-06 27.7 0.0 0.0035 16.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_14 PF13173.1 KEG08398.1 - 2.3e-06 27.5 0.0 8.2e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KEG08398.1 - 7.1e-05 22.6 0.0 0.27 10.8 0.0 3.2 2 1 0 3 3 3 1 Archaeal ATPase Mg_chelatase PF01078.16 KEG08398.1 - 0.00022 20.4 0.0 0.019 14.1 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KEG08398.1 - 0.00026 21.1 0.0 0.38 10.9 0.0 2.5 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.7 KEG08398.1 - 0.00044 19.9 0.0 0.17 11.5 0.0 2.7 2 0 0 2 2 2 1 NACHT domain ABC_tran PF00005.22 KEG08398.1 - 0.00056 20.2 0.0 0.72 10.1 0.0 2.9 3 0 0 3 3 3 1 ABC transporter RuvB_N PF05496.7 KEG08398.1 - 0.00082 18.4 0.0 0.0028 16.7 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Sigma54_activat PF00158.21 KEG08398.1 - 0.0014 18.1 0.0 0.37 10.2 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 KEG08398.1 - 0.0015 18.6 0.0 2 8.4 0.0 3.2 3 0 0 3 3 3 1 Sigma-54 interaction domain TIP49 PF06068.8 KEG08398.1 - 0.0016 17.2 0.0 0.011 14.4 0.0 2.0 2 0 0 2 2 2 1 TIP49 C-terminus AAA_19 PF13245.1 KEG08398.1 - 0.0019 17.9 2.2 0.59 9.9 0.0 3.3 4 0 0 4 4 2 1 Part of AAA domain AAA_2 PF07724.9 KEG08398.1 - 0.0026 17.6 0.0 0.059 13.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) KTI12 PF08433.5 KEG08398.1 - 0.0028 16.8 0.0 0.048 12.8 0.0 2.6 3 0 0 3 3 3 1 Chromatin associated protein KTI12 AAA_3 PF07726.6 KEG08398.1 - 0.0037 16.8 0.0 0.03 13.9 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KEG08398.1 - 0.0048 16.3 1.0 1.5 8.1 0.2 3.2 2 1 1 3 3 3 1 AAA domain AFG1_ATPase PF03969.11 KEG08398.1 - 0.0059 15.4 0.0 0.092 11.5 0.0 2.2 2 0 0 2 2 2 1 AFG1-like ATPase AAA_18 PF13238.1 KEG08398.1 - 0.0063 16.8 0.0 0.089 13.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 KEG08398.1 - 0.0064 15.5 0.0 1.6 7.5 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) SKI PF01202.17 KEG08398.1 - 0.0069 16.2 0.0 0.024 14.5 0.0 1.9 2 0 0 2 2 2 1 Shikimate kinase MCM PF00493.18 KEG08398.1 - 0.016 14.0 0.0 0.085 11.6 0.0 1.9 2 0 0 2 2 2 0 MCM2/3/5 family AAA_29 PF13555.1 KEG08398.1 - 0.019 14.4 0.0 12 5.5 0.0 3.2 3 0 0 3 3 2 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KEG08398.1 - 0.024 14.1 0.0 3.3 7.1 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family PhoH PF02562.11 KEG08398.1 - 0.054 12.7 0.0 0.49 9.5 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein UPF0079 PF02367.12 KEG08398.1 - 0.11 12.1 0.0 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 VGLL4 PF15245.1 KEG08399.1 - 0.017 14.9 0.4 0.017 14.9 0.3 1.1 1 0 0 1 1 1 0 Transcription cofactor vestigial-like protein 4 WD40 PF00400.27 KEG08400.1 - 2.3e-20 71.6 10.7 6.2e-08 32.2 0.2 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KEG08400.1 - 0.06 11.6 0.1 0.18 10.0 0.0 1.7 2 0 0 2 2 2 0 Cytochrome D1 heme domain DUF4429 PF14472.1 KEG08400.1 - 0.065 13.5 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4429) F-box-like PF12937.2 KEG08402.1 - 9.7e-07 28.4 0.9 2.2e-06 27.3 0.6 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KEG08402.1 - 6.2e-05 22.5 0.2 0.00013 21.5 0.1 1.5 1 0 0 1 1 1 1 F-box domain His_Phos_2 PF00328.17 KEG08404.1 - 1.7e-18 67.0 0.0 1.9e-13 50.5 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Pkinase PF00069.20 KEG08405.1 - 7.7e-45 153.0 0.0 4.1e-44 150.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG08405.1 - 8.8e-19 67.5 0.0 5e-18 65.1 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KEG08405.1 - 0.01 15.5 0.0 0.037 13.7 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KEG08405.1 - 0.021 13.9 0.1 0.054 12.5 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KEG08405.1 - 0.036 13.3 0.1 0.079 12.3 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Thioredoxin_7 PF13899.1 KEG08406.1 - 0.00019 21.3 0.1 0.0013 18.7 0.0 2.3 2 1 0 2 2 2 1 Thioredoxin-like DUF427 PF04248.7 KEG08406.1 - 0.0011 18.6 0.1 0.0055 16.3 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF427) Thioredoxin_2 PF13098.1 KEG08406.1 - 0.096 12.8 0.0 0.24 11.5 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin-like domain PQ-loop PF04193.9 KEG08407.1 - 2.2e-26 91.1 3.3 1.2e-14 53.5 0.1 2.5 2 0 0 2 2 2 2 PQ loop repeat HCV_NS1 PF01560.12 KEG08407.1 - 0.066 11.6 0.0 0.11 10.9 0.0 1.2 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein E2/NS1 OapA_N PF08525.6 KEG08410.1 - 0.00079 19.1 3.2 6.5 6.6 0.2 3.3 1 1 2 3 3 3 3 Opacity-associated protein A N-terminal motif Pilus_PilP PF11356.3 KEG08411.1 - 0.069 13.3 0.3 0.34 11.1 0.2 2.2 2 0 0 2 2 2 0 Type IV pilus biogenesis PknH_C PF14032.1 KEG08411.1 - 0.08 12.4 0.5 0.82 9.2 0.4 2.2 1 1 1 2 2 2 0 PknH-like extracellular domain MGC-24 PF05283.6 KEG08415.1 - 0.0062 16.3 2.2 0.0062 16.3 1.5 3.4 1 1 0 3 3 3 1 Multi-glycosylated core protein 24 (MGC-24) FliJ PF02050.11 KEG08415.1 - 0.98 9.4 28.9 0.71 9.9 5.6 4.0 3 1 1 4 4 4 0 Flagellar FliJ protein Pex14_N PF04695.8 KEG08418.1 - 8.4 6.4 7.1 16 5.5 4.9 1.5 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Blo-t-5 PF11642.3 KEG08419.1 - 0.0061 16.2 2.1 0.01 15.6 1.4 1.4 1 0 0 1 1 1 1 Mite allergen Blo t 5 T2SF PF00482.18 KEG08419.1 - 0.021 14.7 0.1 1 9.2 0.0 2.5 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F IFT57 PF10498.4 KEG08419.1 - 0.036 12.8 3.1 0.082 11.6 0.3 2.0 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 ERM PF00769.14 KEG08419.1 - 0.046 13.2 8.6 0.035 13.6 3.0 1.9 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF3450 PF11932.3 KEG08419.1 - 0.057 12.6 6.2 0.074 12.2 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) PEP-utilisers_N PF05524.8 KEG08419.1 - 0.058 13.1 7.8 0.11 12.3 5.4 1.5 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal TMCO5 PF14992.1 KEG08419.1 - 0.1 11.6 3.4 0.13 11.3 2.4 1.1 1 0 0 1 1 1 0 TMCO5 family DUF641 PF04859.7 KEG08419.1 - 0.33 10.7 5.0 0.47 10.2 3.5 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) CENP-Q PF13094.1 KEG08419.1 - 0.56 10.2 16.2 0.085 12.8 5.9 2.1 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF724 PF05266.9 KEG08419.1 - 0.76 9.3 5.5 1.5 8.4 3.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Fmp27_WPPW PF10359.4 KEG08419.1 - 1.3 7.3 4.7 1.5 7.1 3.3 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain TPR_7 PF13176.1 KEG08419.1 - 1.7 8.5 6.0 49 4.0 0.1 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat APG6 PF04111.7 KEG08419.1 - 2 7.4 6.5 2.5 7.0 4.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Rab5-bind PF09311.6 KEG08419.1 - 2.1 8.1 14.4 5.1 6.9 10.0 1.6 1 1 0 1 1 1 0 Rabaptin-like protein Lzipper-MIP1 PF14389.1 KEG08419.1 - 5.5 7.1 11.6 1.1 9.3 4.3 2.4 1 1 2 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 DUF1087 PF06465.8 KEG08420.1 - 0.055 13.3 0.3 53 3.8 0.0 3.1 2 1 1 3 3 3 0 Domain of Unknown Function (DUF1087) UPF0731 PF14982.1 KEG08420.1 - 3.3 7.6 5.7 3.4 7.6 0.2 2.3 2 0 0 2 2 2 0 UPF0731 family MT PF12777.2 KEG08421.1 - 1.3e-08 33.9 0.0 4.1e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor IFT57 PF10498.4 KEG08421.1 - 0.17 10.5 44.1 0.059 12.1 3.9 4.4 4 1 1 5 5 5 0 Intra-flagellar transport protein 57 TFIIS_C PF01096.13 KEG08421.1 - 0.18 11.4 1.1 24 4.6 0.1 2.7 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) TPR_7 PF13176.1 KEG08421.1 - 1.3 8.9 16.6 0.98 9.3 0.1 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TIR-like PF10137.4 KEG08421.1 - 2.5 7.7 5.8 2.5 7.7 0.2 3.2 3 0 0 3 3 3 0 Predicted nucleotide-binding protein containing TIR-like domain RDM PF11002.3 KEG08421.1 - 5.9 6.6 14.5 5.9 6.6 0.1 4.7 5 0 0 5 5 5 0 RFPL defining motif (RDM) Prefoldin PF02996.12 KEG08422.1 - 2.4e-09 36.8 0.0 4.6e-09 35.9 0.0 1.7 1 1 0 1 1 1 1 Prefoldin subunit Torsin PF06309.6 KEG08424.1 - 1.7e-05 24.7 0.0 3.5e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Torsin AAA PF00004.24 KEG08424.1 - 0.00054 20.1 0.0 0.0034 17.5 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEG08424.1 - 0.013 15.4 0.1 0.034 14.1 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain DUF1726 PF08351.6 KEG08424.1 - 0.02 14.5 0.1 8.7 6.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1726) AAA_19 PF13245.1 KEG08424.1 - 0.037 13.7 1.5 0.47 10.2 0.1 3.2 3 0 0 3 3 3 0 Part of AAA domain Methyltransf_24 PF13578.1 KEG08424.1 - 0.12 13.1 0.3 14 6.5 0.0 2.8 2 0 0 2 2 2 0 Methyltransferase domain CAP_N PF01213.14 KEG08424.1 - 2 7.6 3.6 3.1 6.9 2.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal FixO PF02433.10 KEG08426.1 - 0.048 13.0 0.2 0.092 12.0 0.1 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO NAD_binding_5 PF07994.7 KEG08427.1 - 6.7e-103 344.2 0.0 8.2e-103 343.9 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 KEG08427.1 - 5.3e-45 151.8 0.0 1.1e-44 150.8 0.0 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase FA_desaturase PF00487.19 KEG08428.1 - 8.5e-38 130.2 16.9 8.5e-38 130.2 11.7 1.6 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 KEG08428.1 - 2e-06 27.4 0.1 4e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain WD40 PF00400.27 KEG08429.1 - 2.4e-07 30.3 2.3 0.037 13.9 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat LisH PF08513.6 KEG08429.1 - 0.0029 17.3 2.9 0.055 13.2 0.4 2.4 2 0 0 2 2 2 1 LisH PQQ_3 PF13570.1 KEG08429.1 - 0.01 16.0 2.2 0.21 11.9 0.0 3.1 2 0 0 2 2 2 0 PQQ-like domain RAB3GAP2_N PF14655.1 KEG08429.1 - 0.099 11.6 0.0 1.5 7.7 0.0 2.3 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Spatacsin_C PF14649.1 KEG08429.1 - 0.17 10.7 0.1 12 4.7 0.0 2.3 2 0 0 2 2 2 0 Spatacsin C-terminus zf-RING_2 PF13639.1 KEG08430.1 - 4.2e-09 36.0 9.3 4.2e-09 36.0 6.4 2.9 2 0 0 2 2 2 1 Ring finger domain PHD PF00628.24 KEG08430.1 - 1.2e-07 31.2 6.9 1.2e-07 31.2 4.8 2.9 3 1 0 3 3 1 1 PHD-finger zf-RING_5 PF14634.1 KEG08430.1 - 6.8e-07 28.9 8.6 6.8e-07 28.9 6.0 2.7 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KEG08430.1 - 7e-06 25.6 8.7 7e-06 25.6 6.1 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KEG08430.1 - 3.9e-05 23.6 5.7 3.9e-05 23.6 3.9 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KEG08430.1 - 5.1e-05 22.8 6.1 5.1e-05 22.8 4.2 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.17 KEG08430.1 - 0.00093 18.8 1.9 0.00093 18.8 1.3 3.1 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-Apc11 PF12861.2 KEG08430.1 - 0.0028 17.4 3.8 0.0028 17.4 2.6 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 KEG08430.1 - 0.016 15.2 9.2 0.016 15.2 6.4 3.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KEG08430.1 - 0.027 14.0 22.9 0.47 10.0 5.9 3.1 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-HC5HC2H PF13771.1 KEG08430.1 - 0.065 13.3 5.7 0.073 13.2 0.3 2.7 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-H2C2_2 PF13465.1 KEG08430.1 - 0.14 12.4 7.9 0.8 10.1 0.3 3.3 3 0 0 3 3 3 0 Zinc-finger double domain zf-C3HC4_4 PF15227.1 KEG08430.1 - 0.15 11.9 14.0 0.24 11.3 3.1 3.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 KEG08430.1 - 1 9.2 5.4 5.5 6.8 3.8 2.2 1 1 1 2 2 2 0 zf-RING of BARD1-type protein DZR PF12773.2 KEG08430.1 - 1.3 8.9 20.7 0.48 10.2 4.4 3.5 2 2 0 2 2 2 0 Double zinc ribbon Rubredoxin PF00301.15 KEG08430.1 - 1.5 8.7 5.9 32 4.4 0.0 4.2 4 0 0 4 4 4 0 Rubredoxin zf-RING_UBOX PF13445.1 KEG08430.1 - 4.6 7.0 11.5 0.19 11.4 2.8 2.5 2 0 0 2 2 2 0 RING-type zinc-finger Pkinase PF00069.20 KEG08431.1 - 1.5e-62 211.0 0.0 1.8e-62 210.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG08431.1 - 1.7e-25 89.6 0.0 4e-25 88.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEG08431.1 - 0.036 13.7 0.6 0.15 11.7 0.1 1.8 1 1 0 2 2 2 0 Phosphotransferase enzyme family Plus-3 PF03126.13 KEG08432.1 - 0.0016 18.4 0.0 0.0056 16.7 0.0 2.0 1 1 0 1 1 1 1 Plus-3 domain Clathrin PF00637.15 KEG08433.1 - 2.6e-05 23.8 0.1 8e-05 22.2 0.1 1.8 1 1 0 1 1 1 1 Region in Clathrin and VPS Vps39_2 PF10367.4 KEG08433.1 - 0.0026 17.8 0.1 0.021 14.9 0.1 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-HC5HC2H_2 PF13832.1 KEG08433.1 - 0.03 14.3 0.7 0.085 12.8 0.1 2.0 2 0 0 2 2 2 0 PHD-zinc-finger like domain zf-RING_2 PF13639.1 KEG08433.1 - 0.068 13.0 4.0 0.41 10.5 2.8 2.4 1 1 1 2 2 2 0 Ring finger domain ASL_C PF08328.6 KEG08433.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal HSP70 PF00012.15 KEG08435.1 - 2.8e-255 847.9 2.7 3.2e-255 847.7 1.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KEG08435.1 - 8.1e-18 64.0 0.6 3.2e-16 58.8 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 KEG08435.1 - 0.00023 20.9 0.6 0.0061 16.3 0.0 3.3 2 1 0 2 2 2 1 Cell division protein FtsA BcrAD_BadFG PF01869.15 KEG08435.1 - 0.018 14.3 0.7 6.3 5.9 0.0 3.0 3 0 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family Ribonuc_L-PSP PF01042.16 KEG08435.1 - 0.046 13.4 0.1 0.19 11.4 0.0 2.1 2 0 0 2 2 2 0 Endoribonuclease L-PSP Nop53 PF07767.6 KEG08436.1 - 0.0062 15.5 12.4 0.0062 15.5 8.6 1.9 1 1 1 2 2 2 1 Nop53 (60S ribosomal biogenesis) NUC153 PF08159.7 KEG08436.1 - 0.091 12.3 0.8 0.49 10.0 0.1 2.5 2 1 0 2 2 2 0 NUC153 domain Ras PF00071.17 KEG08437.1 - 6.3e-10 38.6 0.0 0.00028 20.3 0.0 2.6 3 0 0 3 3 3 2 Ras family Miro PF08477.8 KEG08437.1 - 1.7e-06 28.5 0.0 0.044 14.2 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein Arf PF00025.16 KEG08437.1 - 0.00033 19.9 0.0 0.76 8.9 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family YABBY PF04690.8 KEG08438.1 - 3.1 8.0 5.1 1.6 8.9 1.9 1.7 1 1 0 1 1 1 0 YABBY protein WD40 PF00400.27 KEG08439.1 - 1.7e-22 78.4 3.5 3e-08 33.2 0.2 4.9 4 1 0 4 4 4 4 WD domain, G-beta repeat PQQ_3 PF13570.1 KEG08439.1 - 0.00037 20.6 0.8 6.8 7.1 0.0 4.8 6 0 0 6 6 6 1 PQQ-like domain CENP-T PF15511.1 KEG08439.1 - 0.048 12.9 30.2 0.021 14.0 12.9 2.2 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T Astro_capsid PF03115.9 KEG08439.1 - 0.22 9.7 5.2 0.27 9.4 3.6 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF2457 PF10446.4 KEG08439.1 - 0.66 8.6 29.2 0.095 11.4 15.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Rhabdo_ncap PF00945.13 KEG08439.1 - 1.5 7.3 9.9 3 6.3 6.9 1.4 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein SDA1 PF05285.7 KEG08439.1 - 2 7.6 33.3 0.034 13.4 17.1 2.0 2 0 0 2 2 2 0 SDA1 Sporozoite_P67 PF05642.6 KEG08439.1 - 2.3 5.9 10.1 0.04 11.7 1.7 1.9 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Daxx PF03344.10 KEG08439.1 - 3.1 6.1 36.5 0.026 13.0 18.3 1.9 2 0 0 2 2 2 0 Daxx Family DUF4614 PF15391.1 KEG08439.1 - 3.3 7.4 11.6 0.96 9.1 2.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) CobT PF06213.7 KEG08439.1 - 6.8 5.7 33.6 0.24 10.4 17.2 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Ribosomal_L29 PF00831.18 KEG08440.1 - 2.8e-16 58.9 5.1 2.8e-16 58.9 3.6 2.3 2 1 0 2 2 2 1 Ribosomal L29 protein MRP-L47 PF06984.8 KEG08440.1 - 0.044 13.6 1.0 0.044 13.6 0.7 2.0 2 1 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF1967 PF09269.6 KEG08440.1 - 0.069 12.8 0.5 0.4 10.3 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1967) Acetyltransf_5 PF13444.1 KEG08440.1 - 0.11 13.0 1.1 0.17 12.5 0.8 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_S9 PF00380.14 KEG08440.1 - 0.28 11.4 7.0 0.44 10.8 4.8 1.4 1 1 0 1 1 1 0 Ribosomal protein S9/S16 EcoEI_R_C PF08463.5 KEG08440.1 - 0.59 9.9 9.5 0.73 9.6 2.4 2.1 1 1 1 2 2 2 0 EcoEI R protein C-terminal Trypan_PARP PF05887.6 KEG08441.1 - 2.3e-05 24.2 23.6 4e-05 23.4 16.4 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) PAT1 PF09770.4 KEG08441.1 - 0.00018 19.9 32.5 0.0002 19.8 22.5 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 KEG08441.1 - 0.0096 15.8 14.3 0.011 15.6 9.9 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 KEG08441.1 - 0.019 14.3 34.5 0.024 14.0 23.9 1.2 1 0 0 1 1 1 0 Vta1 like Suf PF05843.9 KEG08441.1 - 0.52 9.9 9.8 0.74 9.4 6.8 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Sec1 PF00995.18 KEG08442.1 - 1.3e-84 284.8 0.0 1.5e-84 284.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family CutC PF03932.9 KEG08444.1 - 5.2e-61 205.4 0.8 6.1e-61 205.2 0.6 1.0 1 0 0 1 1 1 1 CutC family AP_endonuc_2 PF01261.19 KEG08444.1 - 1.4e-05 24.5 0.2 3e-05 23.4 0.1 1.7 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel Glyco_hydro_97 PF10566.4 KEG08444.1 - 0.066 12.3 0.0 0.085 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycoside hydrolase 97 ANTH PF07651.11 KEG08445.1 - 2.7e-32 111.6 0.0 3.5e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 KEG08445.1 - 3e-09 36.7 0.5 5.9e-09 35.8 0.4 1.5 1 0 0 1 1 1 1 ENTH domain RepA_N PF06970.6 KEG08445.1 - 0.11 12.3 0.0 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Replication initiator protein A (RepA) N-terminus HisKA PF00512.20 KEG08446.1 - 0.2 11.6 7.2 7.2 6.6 0.1 4.3 3 1 0 3 3 3 0 His Kinase A (phospho-acceptor) domain DUF2508 PF10704.4 KEG08446.1 - 0.35 11.0 14.1 1.6 8.9 0.4 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF2508) BCDHK_Adom3 PF10436.4 KEG08447.1 - 1.1e-34 119.3 0.0 1.6e-34 118.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KEG08447.1 - 6.1e-06 25.9 0.0 1.2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KEG08447.1 - 0.002 17.7 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CENP-Q PF13094.1 KEG08449.1 - 0.19 11.7 44.8 0.43 10.5 2.3 3.2 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF2046 PF09755.4 KEG08449.1 - 2.2 7.1 35.8 1 8.1 18.8 3.2 2 1 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) Reo_sigmaC PF04582.7 KEG08449.1 - 3.1 6.8 13.0 1.7 7.7 3.4 2.9 2 1 1 3 3 3 0 Reovirus sigma C capsid protein MscS_porin PF12795.2 KEG08449.1 - 6.5 5.9 42.0 0.18 11.1 0.3 3.2 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain GDA1_CD39 PF01150.12 KEG08450.1 - 6.1e-70 235.8 0.0 8.8e-70 235.3 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 KEG08450.1 - 0.00014 21.1 0.0 0.00032 19.9 0.0 1.6 1 0 0 1 1 1 1 Ppx/GppA phosphatase family LRR_4 PF12799.2 KEG08451.1 - 9.8e-18 63.3 10.2 1.3e-07 31.0 2.0 3.4 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG08451.1 - 4.2e-16 58.4 28.0 2.7e-07 30.2 3.3 2.7 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 KEG08451.1 - 2.6e-10 38.8 13.1 0.21 11.7 0.7 6.3 6 1 1 7 7 7 4 Leucine Rich Repeat LRR_6 PF13516.1 KEG08451.1 - 0.00011 21.9 10.1 3.8 7.8 0.0 5.4 4 1 1 5 5 5 2 Leucine Rich repeat LRR_7 PF13504.1 KEG08451.1 - 0.0017 18.2 22.3 1.9 9.0 0.4 6.1 6 0 0 6 6 6 2 Leucine rich repeat NPV_P10 PF05531.7 KEG08452.1 - 0.00061 19.9 0.1 0.00061 19.9 0.1 2.0 2 0 0 2 2 2 1 Nucleopolyhedrovirus P10 protein DUF445 PF04286.7 KEG08452.1 - 0.016 14.7 3.8 0.021 14.4 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF4613 PF15390.1 KEG08452.1 - 0.018 13.2 6.3 0.021 13.0 4.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Med8 PF10232.4 KEG08452.1 - 0.029 13.8 3.8 0.04 13.4 2.6 1.2 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 BamHI PF02923.10 KEG08452.1 - 0.055 13.4 0.0 0.077 12.9 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease BamHI IpaD PF06511.6 KEG08452.1 - 0.46 9.4 5.8 0.62 9.0 4.0 1.2 1 0 0 1 1 1 0 Invasion plasmid antigen IpaD DUF3847 PF12958.2 KEG08452.1 - 0.53 10.0 9.3 0.56 10.0 1.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3847) AAA_13 PF13166.1 KEG08452.1 - 0.55 8.6 5.5 0.68 8.3 3.8 1.0 1 0 0 1 1 1 0 AAA domain LacI PF00356.16 KEG08452.1 - 0.59 9.7 5.5 0.53 9.9 0.2 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family Vfa1 PF08432.5 KEG08452.1 - 0.88 9.5 5.9 1.1 9.1 4.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Fib_alpha PF08702.5 KEG08452.1 - 2.4 8.2 7.0 5.4 7.1 4.9 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Borrelia_P83 PF05262.6 KEG08452.1 - 2.5 6.2 10.6 3.2 5.8 7.3 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4557 PF15101.1 KEG08452.1 - 2.7 7.7 6.8 3.8 7.3 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) MFS_1 PF07690.11 KEG08453.1 - 1.1e-16 60.5 21.4 6.4e-15 54.7 10.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily EF-hand_6 PF13405.1 KEG08455.1 - 0.00028 20.5 0.3 0.00098 18.8 0.2 1.9 1 0 0 1 1 1 1 EF-hand domain WD40 PF00400.27 KEG08455.1 - 0.00054 19.7 10.9 0.019 14.8 0.1 4.7 6 0 0 6 6 6 2 WD domain, G-beta repeat EF-hand_1 PF00036.27 KEG08455.1 - 0.0015 17.7 0.3 0.0034 16.5 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 KEG08455.1 - 0.0034 16.6 0.6 0.0085 15.4 0.4 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 KEG08455.1 - 0.006 16.6 0.1 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 KEG08455.1 - 0.029 13.9 0.3 0.098 12.2 0.2 1.9 1 0 0 1 1 1 0 EF-hand domain pair Dynein_light PF01221.13 KEG08456.1 - 2.7e-17 62.5 0.1 7.2e-15 54.7 0.0 2.1 2 0 0 2 2 2 2 Dynein light chain type 1 Ground-like PF04155.13 KEG08456.1 - 1.5e-08 34.8 0.1 6.1e-08 32.8 0.1 1.8 1 1 0 1 1 1 1 Ground-like domain cIII PF08134.6 KEG08456.1 - 0.053 13.1 1.8 1.9 8.1 0.0 2.8 3 0 0 3 3 3 0 cIII protein family Tombus_movement PF05318.7 KEG08456.1 - 0.094 13.3 0.0 0.15 12.7 0.0 1.3 1 0 0 1 1 1 0 Tombusvirus movement protein MscL PF01741.13 KEG08456.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL Utp21 PF04192.7 KEG08457.1 - 2.1e-21 76.1 0.0 3.3e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 KEG08457.1 - 5e-19 67.3 4.4 9.6e-07 28.4 0.0 7.4 8 0 0 8 8 8 4 WD domain, G-beta repeat PQQ_2 PF13360.1 KEG08457.1 - 7.5e-08 32.1 0.1 1e-05 25.1 0.0 2.5 2 0 0 2 2 2 2 PQQ-like domain Nup160 PF11715.3 KEG08457.1 - 0.0018 16.4 0.2 0.085 10.9 0.0 2.7 3 0 0 3 3 3 1 Nucleoporin Nup120/160 SpoIIIAH PF12685.2 KEG08457.1 - 1.8 7.9 4.3 3 7.2 3.0 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Adaptin_binding PF10199.4 KEG08459.1 - 0.00054 20.2 0.0 0.0026 18.0 0.0 2.0 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 UDPGP PF01704.13 KEG08462.1 - 1.5e-08 33.5 0.0 2.1e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase XRN_N PF03159.13 KEG08463.1 - 3.4e-62 209.9 0.0 2.5e-61 207.1 0.0 2.1 1 1 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus FA_desaturase PF00487.19 KEG08463.1 - 0.002 17.5 0.0 0.0057 16.1 0.0 1.7 2 0 0 2 2 2 1 Fatty acid desaturase zf-RanBP PF00641.13 KEG08463.1 - 0.013 14.6 3.3 0.026 13.6 2.3 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Macoilin PF09726.4 KEG08465.1 - 0.059 11.6 1.6 0.12 10.6 0.1 1.8 2 0 0 2 2 2 0 Transmembrane protein DnaJ PF00226.26 KEG08466.1 - 7.9e-10 38.3 0.9 1.6e-09 37.3 0.6 1.5 1 0 0 1 1 1 1 DnaJ domain Big_3_4 PF13754.1 KEG08466.1 - 0.032 14.5 0.2 0.063 13.6 0.1 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) NARP1 PF12569.3 KEG08467.1 - 2.8e-86 290.3 19.0 8.3e-83 278.8 8.5 3.0 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 KEG08467.1 - 8.2e-16 57.4 13.4 0.00018 21.0 0.4 5.8 5 1 0 5 5 5 3 TPR repeat TPR_1 PF00515.23 KEG08467.1 - 7.7e-11 41.1 10.1 2.4e-05 23.7 0.0 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEG08467.1 - 9e-11 42.1 15.9 0.02 15.5 0.0 7.0 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEG08467.1 - 3.5e-08 32.7 21.3 0.0082 15.9 0.0 8.7 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEG08467.1 - 2.4e-07 30.5 21.4 0.00042 20.1 1.1 5.9 4 2 2 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEG08467.1 - 4.9e-06 26.7 15.6 2.2 8.6 1.0 6.0 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 KEG08467.1 - 8.3e-05 22.4 3.8 0.32 11.3 0.0 6.1 7 0 0 7 7 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KEG08467.1 - 0.00025 20.8 0.8 0.59 10.0 0.1 3.9 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.1 KEG08467.1 - 0.00033 20.2 6.0 0.31 10.9 0.0 5.6 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEG08467.1 - 0.00036 20.9 22.5 0.0061 17.0 0.0 8.3 5 3 4 9 9 8 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEG08467.1 - 0.00094 18.7 11.0 0.29 10.9 0.0 6.7 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 KEG08467.1 - 0.00096 18.9 5.2 0.024 14.4 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat Sec10 PF07393.6 KEG08467.1 - 0.0095 14.1 0.1 0.2 9.7 0.0 2.1 2 0 0 2 2 2 1 Exocyst complex component Sec10 DUF778 PF05608.7 KEG08468.1 - 3.8e-40 136.9 0.0 4.6e-40 136.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF778) Peptidase_C97 PF05903.9 KEG08468.1 - 0.022 14.5 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 PPPDE putative peptidase domain LRAT PF04970.8 KEG08468.1 - 0.029 14.3 0.1 0.04 13.8 0.1 1.2 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Arif-1 PF06770.6 KEG08468.1 - 0.21 10.9 1.1 0.23 10.7 0.0 1.6 2 1 0 2 2 2 0 Actin-rearrangement-inducing factor (Arif-1) ADK PF00406.17 KEG08469.1 - 1.7e-39 135.1 0.0 2.3e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.1 KEG08469.1 - 0.00016 22.4 0.1 0.00034 21.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain ADK_lid PF05191.9 KEG08469.1 - 0.00018 21.1 0.0 0.00036 20.1 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA PF00004.24 KEG08469.1 - 0.0013 18.9 0.0 0.004 17.3 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 KEG08469.1 - 0.0016 18.7 0.3 0.0057 16.9 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KEG08469.1 - 0.0097 15.7 0.0 0.037 13.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain DnaJ PF00226.26 KEG08470.1 - 1e-21 76.3 0.8 1.9e-21 75.5 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain MORN PF02493.15 KEG08471.1 - 1.4e-53 175.4 149.0 0.00022 20.7 2.5 27.6 27 0 0 27 27 27 22 MORN repeat FYVE PF01363.16 KEG08471.1 - 2.8e-24 84.7 24.3 4.5e-18 64.9 8.9 2.4 2 0 0 2 2 2 2 FYVE zinc finger FYVE_2 PF02318.11 KEG08471.1 - 0.0011 18.8 15.6 0.069 13.0 4.8 2.4 2 0 0 2 2 2 2 FYVE-type zinc finger IBR PF01485.16 KEG08471.1 - 4.8 7.1 14.6 1.3 8.9 1.4 2.5 2 0 0 2 2 2 0 IBR domain Cyt-b5 PF00173.23 KEG08472.1 - 2.4e-20 72.0 0.2 4.5e-20 71.2 0.0 1.6 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Zip PF02535.17 KEG08472.1 - 0.099 11.6 0.2 0.11 11.5 0.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CTP_transf_2 PF01467.21 KEG08473.1 - 3.8e-09 36.8 0.0 1.3e-08 35.0 0.0 1.7 1 1 0 1 1 1 1 Cytidylyltransferase FAD_syn PF06574.7 KEG08473.1 - 0.048 13.2 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 FAD synthetase EF-hand_1 PF00036.27 KEG08473.1 - 0.14 11.5 0.0 0.42 10.0 0.0 1.7 1 0 0 1 1 1 0 EF hand ABC_tran PF00005.22 KEG08474.1 - 1.6e-20 73.7 0.0 4.5e-20 72.3 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KEG08474.1 - 4.4e-07 30.1 0.1 0.0075 16.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KEG08474.1 - 7.8e-05 22.7 0.1 0.00017 21.6 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 KEG08474.1 - 8.1e-05 21.8 1.0 0.00038 19.6 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SMC_N PF02463.14 KEG08474.1 - 0.00035 19.8 0.1 0.0058 15.8 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KEG08474.1 - 0.00042 19.7 0.1 0.0019 17.6 0.1 2.1 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 KEG08474.1 - 0.0015 17.6 0.1 0.064 12.3 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.1 KEG08474.1 - 0.0028 17.5 0.0 0.011 15.5 0.0 2.1 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 KEG08474.1 - 0.0088 16.1 0.3 0.03 14.4 0.2 2.0 1 1 0 1 1 1 1 AAA domain ABC_membrane PF00664.18 KEG08474.1 - 0.014 14.8 8.3 0.043 13.2 5.8 1.7 1 1 0 1 1 1 0 ABC transporter transmembrane region AAA_23 PF13476.1 KEG08474.1 - 0.015 15.5 0.0 0.027 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.1 KEG08474.1 - 0.12 10.8 0.0 0.18 10.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Slu7 PF11708.3 KEG08475.1 - 0.16 11.7 2.7 0.26 11.0 1.9 1.3 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor Ras PF00071.17 KEG08477.1 - 2.2e-60 202.7 0.4 2.6e-60 202.4 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEG08477.1 - 1.4e-18 67.4 0.0 2.5e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEG08477.1 - 3e-14 52.6 0.1 3.6e-14 52.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KEG08477.1 - 1.5e-06 27.5 0.1 1.9e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KEG08477.1 - 9.1e-05 21.9 0.2 0.00028 20.3 0.2 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KEG08477.1 - 0.00022 21.1 0.0 0.00044 20.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KEG08477.1 - 0.02 15.0 0.0 0.045 13.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 KEG08477.1 - 0.026 13.6 0.0 0.054 12.6 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 KEG08477.1 - 0.03 13.8 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KEG08477.1 - 0.03 14.2 0.0 0.043 13.8 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain DUF89 PF01937.14 KEG08477.1 - 0.082 11.6 0.2 0.1 11.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF89 AAA_29 PF13555.1 KEG08477.1 - 0.092 12.2 0.0 0.32 10.5 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRPRB PF09439.5 KEG08477.1 - 0.1 11.7 0.1 0.27 10.4 0.1 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit DAP3 PF10236.4 KEG08477.1 - 0.12 11.2 0.1 0.27 10.1 0.0 1.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 A_deaminase PF00962.17 KEG08479.1 - 1.3e-80 270.8 0.0 1.3e-73 247.8 0.0 2.9 2 1 1 3 3 3 2 Adenosine/AMP deaminase DUF2605 PF10792.4 KEG08482.1 - 0.017 14.7 0.1 0.48 10.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2605) C2 PF00168.25 KEG08484.1 - 1.3e-14 53.7 0.1 3.9e-13 49.0 0.0 2.5 2 0 0 2 2 2 1 C2 domain DUF2404 PF10296.4 KEG08484.1 - 0.0079 16.3 0.0 0.026 14.6 0.0 1.9 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) RRM_1 PF00076.17 KEG08486.1 - 6.9e-14 51.2 0.0 1e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG08486.1 - 1.6e-12 47.2 0.0 2.6e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG08486.1 - 2e-06 27.5 0.0 4.1e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1183 PF06682.7 KEG08486.1 - 0.21 11.1 4.1 0.28 10.7 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF2763 PF10961.3 KEG08486.1 - 3.1 8.2 8.6 6.1 7.3 5.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) Hus1 PF04005.7 KEG08487.1 - 1.9e-63 214.1 0.0 2.4e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 Hus1-like protein TFIIF_alpha PF05793.7 KEG08487.1 - 0.5 8.6 6.6 0.7 8.1 4.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2967 PF11179.3 KEG08487.1 - 0.74 9.2 4.1 0.15 11.5 0.6 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2967) Spt5_N PF11942.3 KEG08487.1 - 1.7 9.3 14.0 2.7 8.6 9.7 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal zf-C3HC4 PF00097.20 KEG08488.1 - 6.4e-05 22.5 6.8 0.00012 21.6 4.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEG08488.1 - 6.8e-05 22.5 6.7 0.00016 21.3 4.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KEG08488.1 - 0.00041 20.1 8.3 0.00072 19.3 5.8 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 KEG08488.1 - 0.001 18.8 4.3 0.0065 16.2 3.0 2.1 1 1 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 KEG08488.1 - 0.0014 18.2 2.1 0.0034 17.0 1.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 KEG08488.1 - 0.015 15.3 9.6 0.029 14.4 6.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEG08488.1 - 0.069 12.9 9.3 0.15 11.9 6.5 1.5 1 0 0 1 1 1 0 Ring finger domain NPL4 PF05021.10 KEG08488.1 - 0.28 10.3 0.1 0.46 9.5 0.0 1.2 1 0 0 1 1 1 0 NPL4 family zf-C3HC4_3 PF13920.1 KEG08488.1 - 0.37 10.4 7.1 0.73 9.5 4.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) adh_short_C2 PF13561.1 KEG08489.1 - 1.2e-19 71.0 0.0 2.2e-19 70.2 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KEG08489.1 - 3.4e-17 62.8 2.5 5.6e-17 62.1 1.8 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KEG08489.1 - 0.0011 18.4 0.1 0.004 16.6 0.1 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KEG08489.1 - 0.0043 16.7 0.1 0.0088 15.7 0.1 1.6 2 0 0 2 2 2 1 KR domain ABC_tran PF00005.22 KEG08490.1 - 1.4e-27 96.6 0.0 2.5e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KEG08490.1 - 1.2e-25 90.5 18.1 1.2e-25 90.5 12.6 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 KEG08490.1 - 9.4e-05 21.7 0.1 0.019 14.1 0.0 2.5 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KEG08490.1 - 0.0009 19.2 0.0 0.11 12.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KEG08490.1 - 0.0015 18.0 0.0 0.0045 16.4 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KEG08490.1 - 0.017 14.6 0.0 0.038 13.4 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_10 PF12846.2 KEG08490.1 - 0.019 14.4 0.0 0.037 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_18 PF13238.1 KEG08490.1 - 0.023 14.9 0.0 2 8.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 KEG08490.1 - 0.031 12.9 0.1 0.055 12.0 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.12 KEG08490.1 - 0.059 13.1 0.1 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_17 PF13207.1 KEG08490.1 - 0.059 14.1 0.0 0.21 12.3 0.0 2.0 2 0 0 2 2 1 0 AAA domain MMR_HSR1 PF01926.18 KEG08490.1 - 0.088 12.7 0.2 0.26 11.2 0.1 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Miro PF08477.8 KEG08490.1 - 0.28 11.7 1.7 0.42 11.1 0.4 1.9 2 0 0 2 2 2 0 Miro-like protein WD40 PF00400.27 KEG08493.1 - 4.5e-19 67.5 23.5 0.00025 20.7 0.2 9.9 10 0 0 10 10 10 6 WD domain, G-beta repeat PQQ_3 PF13570.1 KEG08493.1 - 0.00052 20.2 1.2 1.6 9.1 0.0 4.5 4 0 0 4 4 4 2 PQQ-like domain DUF3097 PF11296.3 KEG08493.1 - 0.022 13.7 0.3 0.038 12.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3097) NMT_C PF02799.10 KEG08494.1 - 2.3e-71 239.1 2.8 5.2e-41 140.1 0.3 3.2 2 1 1 3 3 3 3 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 KEG08494.1 - 4.2e-59 198.7 0.1 3.7e-33 114.4 0.0 2.2 2 0 0 2 2 2 2 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Clat_adaptor_s PF01217.15 KEG08496.1 - 2.4e-34 118.0 4.3 4.3e-18 65.4 1.0 2.0 2 0 0 2 2 2 2 Clathrin adaptor complex small chain LMWPc PF01451.16 KEG08497.1 - 5.1e-11 43.0 0.2 9e-11 42.2 0.1 1.4 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase BTAD PF03704.12 KEG08498.1 - 0.0076 16.5 17.9 0.056 13.7 6.7 2.1 1 1 1 2 2 2 2 Bacterial transcriptional activator domain cwf21 PF08312.7 KEG08498.1 - 1.1 9.1 11.9 0.24 11.2 0.2 2.6 3 0 0 3 3 3 0 cwf21 domain Voltage_CLC PF00654.15 KEG08499.1 - 4.5e-89 298.9 32.9 2.4e-88 296.5 20.2 2.1 2 0 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.23 KEG08499.1 - 3.1e-07 30.0 0.0 0.0015 18.2 0.0 2.5 2 0 0 2 2 2 2 CBS domain DUF2407_C PF13373.1 KEG08499.1 - 0.99 9.3 0.0 0.99 9.3 0.0 2.7 4 0 0 4 4 4 0 DUF2407 C-terminal domain DUF2605 PF10792.4 KEG08500.1 - 2.2 8.0 6.6 3.2 7.4 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2605) LSM PF01423.17 KEG08501.1 - 2.5e-05 23.7 0.0 4.9e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 LSM domain DUF3534 PF12053.3 KEG08503.1 - 0.0011 18.8 0.1 0.0014 18.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3534) Fels1 PF05666.6 KEG08503.1 - 0.079 12.3 0.3 0.13 11.6 0.2 1.3 1 0 0 1 1 1 0 Fels-1 Prophage Protein-like DUF2838 PF10998.3 KEG08506.1 - 1.6e-21 76.2 6.2 1.8e-20 72.8 2.0 3.7 4 0 0 4 4 4 2 Protein of unknown function (DUF2838) DUF4515 PF14988.1 KEG08512.1 - 0.0014 18.3 7.3 0.0014 18.3 5.1 2.3 2 1 1 3 3 3 1 Domain of unknown function (DUF4515) bZIP_2 PF07716.10 KEG08512.1 - 0.017 14.9 1.1 0.017 14.9 0.8 4.8 2 1 1 4 4 4 0 Basic region leucine zipper CASP_C PF08172.7 KEG08512.1 - 0.021 13.8 4.4 0.034 13.1 3.0 1.4 1 0 0 1 1 1 0 CASP C terminal UPF0242 PF06785.6 KEG08512.1 - 0.32 9.6 6.1 0.47 9.0 4.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) DUF3972 PF13118.1 KEG08512.1 - 0.36 10.8 7.0 1.3 9.0 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3972) DUF342 PF03961.8 KEG08512.1 - 0.51 8.6 8.2 0.79 8.0 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Spc7 PF08317.6 KEG08512.1 - 0.72 8.4 11.0 1.3 7.6 7.6 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein CheY-binding PF09078.6 KEG08512.1 - 0.94 9.5 3.4 0.93 9.5 0.3 2.3 2 1 0 2 2 2 0 CheY binding FimP PF09766.4 KEG08512.1 - 1.3 8.0 8.9 2.1 7.3 6.1 1.3 1 0 0 1 1 1 0 Fms-interacting protein DUF310 PF03750.8 KEG08512.1 - 1.5 8.9 5.5 2.7 8.1 3.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF310) Tropomyosin_1 PF12718.2 KEG08512.1 - 1.6 8.6 24.8 0.03 14.1 11.8 1.9 2 1 0 2 2 2 0 Tropomyosin like Herpes_UL6 PF01763.11 KEG08512.1 - 8 4.4 8.3 11 4.0 5.7 1.3 1 1 0 1 1 1 0 Herpesvirus UL6 like Leu_zip PF15294.1 KEG08512.1 - 9.4 5.2 18.0 2.5 7.1 9.1 2.2 2 1 0 2 2 2 0 Leucine zipper Striatin PF08232.7 KEG08512.1 - 9.8 6.4 15.6 46 4.3 10.8 2.3 1 1 0 1 1 1 0 Striatin family zf-CW PF07496.10 KEG08514.1 - 2.7e-10 39.8 5.2 4.4e-10 39.0 3.6 1.4 1 0 0 1 1 1 1 CW-type Zinc Finger Calc_CGRP_IAPP PF00214.14 KEG08514.1 - 0.037 14.0 0.1 0.052 13.5 0.1 1.2 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family DUF2477 PF10631.4 KEG08514.1 - 0.038 14.2 0.6 0.059 13.5 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) zf-TFIIB PF13453.1 KEG08515.1 - 0.26 10.5 2.7 0.48 9.6 1.9 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger CTP_transf_1 PF01148.15 KEG08516.1 - 1.1e-35 123.5 14.6 8.5e-35 120.6 10.1 2.1 1 1 0 1 1 1 1 Cytidylyltransferase family DUF46 PF01864.12 KEG08516.1 - 0.0013 18.6 0.6 0.0037 17.1 0.4 1.7 1 0 0 1 1 1 1 Putative integral membrane protein DUF46 P12 PF12669.2 KEG08516.1 - 0.11 12.7 1.4 0.78 9.9 0.0 2.8 3 0 0 3 3 3 0 Virus attachment protein p12 family FYVE PF01363.16 KEG08517.1 - 5.4e-14 51.8 18.0 9.7e-14 51.0 12.5 1.4 1 0 0 1 1 1 1 FYVE zinc finger TPR_11 PF13414.1 KEG08518.1 - 1e-22 79.5 21.2 6.1e-11 41.7 0.4 4.7 4 1 1 5 5 5 3 TPR repeat TPR_2 PF07719.12 KEG08518.1 - 4.6e-13 48.0 18.0 0.1 12.5 0.0 6.7 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.23 KEG08518.1 - 4.4e-10 38.7 18.3 0.015 14.9 0.0 6.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 KEG08518.1 - 3.9e-08 33.7 1.5 3.9e-08 33.7 1.1 4.5 5 0 0 5 5 4 3 Tetratricopeptide repeat CS PF04969.11 KEG08518.1 - 1.7e-07 31.6 0.0 2.9e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 CS domain TPR_12 PF13424.1 KEG08518.1 - 5e-07 29.5 11.6 0.032 14.1 1.3 4.5 3 2 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 KEG08518.1 - 2.4e-06 27.7 4.9 6.8e-05 23.1 0.1 3.4 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEG08518.1 - 9.2e-05 21.9 9.7 0.24 11.2 0.1 6.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 KEG08518.1 - 0.0001 22.5 18.6 0.002 18.6 0.7 5.5 4 2 1 5 5 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 KEG08518.1 - 0.00039 20.2 9.6 0.51 10.3 0.2 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 KEG08518.1 - 0.00073 19.3 12.3 0.22 11.4 0.1 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEG08518.1 - 0.049 13.4 2.0 31 4.6 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 KEG08518.1 - 0.64 10.6 7.0 3.7 8.2 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEG08518.1 - 1.1 9.8 6.6 2.8 8.5 0.9 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Ycf1 PF05758.7 KEG08518.1 - 3.1 5.3 6.7 4 5.0 4.6 1.1 1 0 0 1 1 1 0 Ycf1 Prefoldin PF02996.12 KEG08519.1 - 8.8e-09 35.0 3.0 1.5e-07 31.0 0.0 2.4 2 1 0 2 2 2 1 Prefoldin subunit Prefoldin_3 PF13758.1 KEG08519.1 - 0.00013 21.6 5.1 0.0055 16.4 0.0 2.4 2 0 0 2 2 2 2 Prefoldin subunit DUF1819 PF08849.6 KEG08519.1 - 0.038 13.4 0.1 0.038 13.4 0.1 2.2 2 0 0 2 2 2 0 Putative inner membrane protein (DUF1819) ApoC-I PF04691.7 KEG08519.1 - 0.32 10.7 2.7 1.4 8.7 0.6 2.5 2 1 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) DUF3775 PF12616.3 KEG08520.1 - 0.025 14.3 2.0 0.035 13.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3775) Amastin PF07344.6 KEG08521.1 - 1.1e-38 132.3 6.0 1.5e-38 131.8 4.2 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein PMP22_Claudin PF00822.15 KEG08521.1 - 0.081 12.5 9.4 0.14 11.7 6.5 1.4 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family PIG-P PF08510.7 KEG08521.1 - 0.19 11.3 1.1 0.22 11.1 0.0 1.7 2 0 0 2 2 2 0 PIG-P Amastin PF07344.6 KEG08522.1 - 2.8e-30 105.0 8.7 3.7e-30 104.5 6.0 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Hydrolase_3 PF08282.7 KEG08523.1 - 1.7e-41 142.5 0.0 1.1e-40 139.9 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 KEG08523.1 - 6.1e-13 48.6 0.0 6.9e-06 25.5 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 KEG08523.1 - 0.00023 21.6 0.0 0.14 12.5 0.0 2.2 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.11 KEG08523.1 - 0.00045 19.1 0.0 0.098 11.5 0.0 2.2 2 0 0 2 2 2 2 Trehalose-phosphatase HAD PF12710.2 KEG08523.1 - 0.00057 20.1 0.1 0.0059 16.7 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Glyoxalase PF00903.20 KEG08523.1 - 0.0011 18.9 0.0 1.8 8.5 0.0 2.8 1 1 1 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Hydrolase_6 PF13344.1 KEG08523.1 - 0.12 12.2 0.0 0.47 10.3 0.0 2.0 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase DUF460 PF04312.8 KEG08523.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF460) zf-CCCH PF00642.19 KEG08524.1 - 3.8e-05 23.2 5.6 3.8e-05 23.2 3.9 2.1 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) IMS PF00817.15 KEG08525.1 - 0.0038 17.0 0.0 0.007 16.1 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IF-2B PF01008.12 KEG08526.1 - 5.9e-36 123.8 0.0 8.1e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family zf-rbx1 PF12678.2 KEG08527.1 - 2.5e-12 46.7 5.3 4.7e-12 45.8 3.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KEG08527.1 - 3e-10 39.7 10.2 5.3e-10 38.9 7.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KEG08527.1 - 2.3e-06 27.5 11.1 4.2e-06 26.6 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KEG08527.1 - 2.7e-06 27.1 8.2 3.8e-06 26.6 4.0 2.3 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 KEG08527.1 - 9.8e-06 25.1 11.5 1.8e-05 24.3 8.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEG08527.1 - 1e-05 25.0 6.7 1.8e-05 24.2 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEG08527.1 - 5.4e-05 22.8 8.8 0.00011 21.8 6.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-HC5HC2H PF13771.1 KEG08527.1 - 0.27 11.3 4.6 0.73 10.0 3.2 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD PF00628.24 KEG08527.1 - 0.31 10.7 9.1 0.74 9.5 6.3 1.7 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.2 KEG08527.1 - 1.4 9.0 10.0 3.1 7.9 6.9 1.6 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 KEG08527.1 - 4.2 7.3 8.0 17 5.4 5.7 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain HC2 PF07382.6 KEG08528.1 - 0.00013 21.9 78.6 0.00032 20.6 54.5 1.7 1 1 0 1 1 1 1 Histone H1-like nucleoprotein HC2 DUF2766 PF10964.3 KEG08528.1 - 1.6 8.6 13.3 0.042 13.7 2.5 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF2766) HC2 PF07382.6 KEG08529.1 - 5.1e-06 26.4 75.7 0.011 15.6 30.0 1.8 1 1 1 2 2 2 2 Histone H1-like nucleoprotein HC2 FLO_LFY PF01698.11 KEG08531.1 - 0.029 13.2 6.5 0.033 13.0 4.5 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein MAD PF05557.8 KEG08531.1 - 0.031 12.3 2.1 0.034 12.2 1.5 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein Osteopontin PF00865.13 KEG08531.1 - 0.036 13.2 2.6 0.044 13.0 1.8 1.0 1 0 0 1 1 1 0 Osteopontin BLOC1_2 PF10046.4 KEG08531.1 - 0.062 13.4 0.2 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GAS PF13851.1 KEG08531.1 - 0.082 12.1 4.4 0.1 11.8 2.9 1.3 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF812 PF05667.6 KEG08531.1 - 0.13 10.6 3.5 0.15 10.5 2.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF964 PF06133.6 KEG08531.1 - 0.27 11.2 3.2 0.52 10.3 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF964) Viral_P18 PF04521.8 KEG08531.1 - 0.38 10.2 4.6 0.33 10.3 2.1 1.7 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein SlyX PF04102.7 KEG08531.1 - 0.46 10.8 2.1 2.3 8.6 0.5 2.2 1 1 1 2 2 2 0 SlyX FliD_N PF02465.13 KEG08531.1 - 0.54 10.6 3.4 0.8 10.1 2.1 1.4 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Herpes_UL25 PF01499.11 KEG08531.1 - 0.55 8.4 7.6 0.64 8.2 5.3 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF1003 PF06210.6 KEG08531.1 - 0.6 10.0 3.4 1.8 8.5 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1003) HSP70 PF00012.15 KEG08531.1 - 0.68 7.7 4.9 0.78 7.5 3.4 1.0 1 0 0 1 1 1 0 Hsp70 protein Seryl_tRNA_N PF02403.17 KEG08531.1 - 1.2 9.1 7.5 0.43 10.6 2.9 1.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.10 KEG08531.1 - 4.2 6.9 6.0 22 4.6 2.7 2.4 1 1 1 2 2 2 0 Septum formation initiator DUF4042 PF13251.1 KEG08532.1 - 4e-11 42.7 0.3 2.8e-10 39.9 0.1 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4042) HEAT_2 PF13646.1 KEG08532.1 - 1.6e-06 28.2 3.8 0.004 17.4 0.2 4.3 4 2 1 5 5 5 3 HEAT repeats HEAT_EZ PF13513.1 KEG08532.1 - 0.21 12.1 9.0 1.6 9.2 0.1 4.2 3 1 1 4 4 4 0 HEAT-like repeat HEAT PF02985.17 KEG08533.1 - 0.00041 20.1 0.4 2.2 8.5 0.0 4.7 4 0 0 4 4 4 1 HEAT repeat Pkinase PF00069.20 KEG08533.1 - 0.002 17.3 0.0 0.0058 15.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Sec10 PF07393.6 KEG08533.1 - 0.28 9.3 0.0 0.42 8.7 0.0 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 PuR_N PF09182.5 KEG08534.1 - 0.0074 15.8 0.0 0.026 14.1 0.0 1.9 1 0 0 1 1 1 1 Bacterial purine repressor, N-terminal SH3_9 PF14604.1 KEG08534.1 - 0.034 13.7 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain Phage_T7_Capsid PF05396.6 KEG08534.1 - 0.06 13.5 0.9 1.1 9.3 0.0 2.7 3 0 0 3 3 3 0 Phage T7 capsid assembly protein V-SNARE_C PF12352.3 KEG08534.1 - 0.1 12.6 3.5 0.38 10.8 0.3 2.7 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus NPV_P10 PF05531.7 KEG08534.1 - 0.16 12.2 4.3 4.7 7.5 0.2 3.1 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.7 KEG08534.1 - 5.2 7.5 15.8 21 5.5 1.8 5.0 4 1 1 5 5 5 0 SlyX AAA_13 PF13166.1 KEG08534.1 - 9.9 4.4 15.1 0.09 11.2 0.4 2.8 2 1 0 3 3 3 0 AAA domain DUF983 PF06170.7 KEG08535.1 - 0.18 11.9 0.0 0.18 11.9 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF983) DZR PF12773.2 KEG08535.1 - 4.2 7.2 61.2 0.04 13.7 1.5 7.1 4 3 3 7 7 7 0 Double zinc ribbon PPR_3 PF13812.1 KEG08536.1 - 1.1e-08 34.7 4.8 0.68 10.3 0.0 6.4 7 0 0 7 7 7 3 Pentatricopeptide repeat domain PPR PF01535.15 KEG08536.1 - 3.4e-07 29.7 8.0 0.089 12.8 0.1 6.7 7 0 0 7 7 7 2 PPR repeat PPR_2 PF13041.1 KEG08536.1 - 1.6e-06 27.9 3.4 0.3 11.1 0.0 6.0 5 1 1 6 6 6 1 PPR repeat family TPR_19 PF14559.1 KEG08536.1 - 0.007 16.6 0.7 4.1 7.8 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat Pneumo_NS1 PF03438.8 KEG08536.1 - 0.16 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Pneumovirus NS1 protein BTAD PF03704.12 KEG08536.1 - 0.28 11.4 8.4 1.5 9.0 0.2 3.7 3 1 0 3 3 3 0 Bacterial transcriptional activator domain Ribosomal_S10 PF00338.17 KEG08537.1 - 1.5e-24 85.6 0.1 1.7e-24 85.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF4590 PF15257.1 KEG08538.1 - 0.1 12.4 0.1 0.25 11.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4590) Macoilin PF09726.4 KEG08538.1 - 2.1 6.5 21.2 6.9 4.8 14.7 1.7 1 1 0 1 1 1 0 Transmembrane protein DUF605 PF04652.11 KEG08538.1 - 5.1 6.3 13.4 7.9 5.7 9.3 1.4 1 0 0 1 1 1 0 Vta1 like Peptidase_M1 PF01433.15 KEG08541.1 - 7.8e-39 133.8 0.0 7.7e-21 74.6 0.0 2.1 2 0 0 2 2 2 2 Peptidase family M1 Peptidase_M1 PF01433.15 KEG08542.1 - 0.0032 16.6 0.0 0.0042 16.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 KEG08542.1 - 0.074 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Peptidase MA superfamily RXT2_N PF08595.6 KEG08543.1 - 3.5 7.4 14.2 24 4.7 0.6 3.5 3 0 0 3 3 3 0 RXT2-like, N-terminal Nucleoplasmin PF03066.10 KEG08543.1 - 8.2 5.9 16.3 1.3 8.4 3.1 2.6 2 0 0 2 2 2 0 Nucleoplasmin Dynamin_N PF00350.18 KEG08545.1 - 2.6e-17 63.1 0.0 1.5e-15 57.3 0.0 2.5 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 KEG08545.1 - 1.9e-08 34.2 0.0 4.5e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Glucodextran_N PF09137.6 KEG08545.1 - 0.067 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Glucodextranase, domain N PAT1 PF09770.4 KEG08545.1 - 8.9 4.4 16.5 12 3.9 11.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 U-box PF04564.10 KEG08547.1 - 0.00011 22.0 0.0 0.00021 21.1 0.0 1.4 1 0 0 1 1 1 1 U-box domain EzrA PF06160.7 KEG08547.1 - 0.0056 14.9 0.1 0.008 14.4 0.1 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Sec34 PF04136.10 KEG08547.1 - 0.0057 16.3 2.4 0.0069 16.1 0.1 2.1 2 1 1 3 3 3 1 Sec34-like family Val_tRNA-synt_C PF10458.4 KEG08547.1 - 0.017 15.1 0.0 0.039 14.0 0.0 1.6 2 0 0 2 2 1 0 Valyl tRNA synthetase tRNA binding arm UCR_hinge PF02320.11 KEG08547.1 - 0.021 14.7 1.3 0.042 13.7 0.4 1.8 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein Dor1 PF04124.7 KEG08547.1 - 0.062 11.7 0.1 0.095 11.1 0.0 1.2 1 0 0 1 1 1 0 Dor1-like family CENP-F_leu_zip PF10473.4 KEG08547.1 - 0.08 12.8 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2937 PF11157.3 KEG08547.1 - 0.088 12.1 0.6 3 7.1 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) DUF677 PF05055.7 KEG08547.1 - 0.11 11.1 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) GAS PF13851.1 KEG08547.1 - 0.11 11.6 0.3 0.21 10.7 0.2 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF972 PF06156.8 KEG08547.1 - 0.99 9.7 7.5 0.27 11.5 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) zf-CCCH PF00642.19 KEG08547.1 - 5.4 6.8 10.2 2.2 8.0 1.9 2.3 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Peptidase_C1 PF00112.18 KEG08551.1 - 4.2e-59 200.0 2.5 5.1e-59 199.7 1.7 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.8 KEG08551.1 - 0.0015 18.1 0.1 0.0031 17.0 0.1 1.5 1 0 0 1 1 1 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.10 KEG08551.1 - 0.13 10.7 2.6 0.097 11.1 0.5 1.6 2 0 0 2 2 2 0 Peptidase C1-like family Amidohydro_4 PF13147.1 KEG08552.1 - 7.8e-11 42.5 0.0 8.6e-10 39.0 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KEG08552.1 - 2.2e-07 30.8 0.3 2.1e-06 27.6 0.2 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KEG08552.1 - 5.8e-06 26.0 0.0 1.3e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KEG08552.1 - 3.7e-05 23.1 0.1 0.18 10.9 0.0 2.5 3 0 0 3 3 3 2 Amidohydrolase family Sulf_coat_C PF12193.3 KEG08552.1 - 0.077 12.8 0.3 0.41 10.4 0.0 2.2 2 0 0 2 2 2 0 Sulfolobus virus coat protein C terminal CTP_transf_2 PF01467.21 KEG08555.1 - 6.4e-10 39.2 0.0 1.1e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase CDP-OH_P_transf PF01066.16 KEG08555.1 - 1.2e-07 31.9 1.4 1.2e-07 31.9 1.0 2.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF1408 PF07193.6 KEG08555.1 - 0.076 12.5 0.1 0.26 10.8 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1408) zf-CCCH PF00642.19 KEG08556.1 - 0.0001 21.8 6.5 0.018 14.7 1.7 2.8 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH PF00642.19 KEG08557.1 - 0.018 14.7 11.8 0.77 9.5 3.2 2.9 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HMG-CoA_red PF00368.13 KEG08559.1 - 1.1e-155 517.9 0.8 1.2e-155 517.7 0.6 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Ribosomal_S26e PF01283.14 KEG08560.1 - 9.9e-40 135.3 2.9 1e-39 135.2 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Peptidase_M8 PF01457.11 KEG08565.1 - 1.9e-137 458.7 0.0 2.3e-137 458.5 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin Reprolysin_5 PF13688.1 KEG08565.1 - 0.04 13.8 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Glyco_transf_64 PF09258.5 KEG08566.1 - 5.4e-16 58.5 0.0 1.2e-14 54.1 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 64 domain tRNA_bind PF01588.15 KEG08567.1 - 5.7e-26 90.1 0.0 8.2e-26 89.6 0.0 1.2 1 0 0 1 1 1 1 Putative tRNA binding domain DUF4139 PF13598.1 KEG08567.1 - 0.039 13.2 0.2 0.053 12.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) Polyketide_cyc PF03364.15 KEG08569.1 - 4.3e-14 52.6 0.2 7.8e-14 51.7 0.2 1.4 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport SOG2 PF10428.4 KEG08569.1 - 0.05 12.2 2.8 0.069 11.7 1.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein E1-E2_ATPase PF00122.15 KEG08570.1 - 3.9e-63 212.5 3.8 8.7e-63 211.4 2.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KEG08570.1 - 2.4e-30 105.3 4.3 2.4e-30 105.3 3.0 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KEG08570.1 - 7.1e-24 85.4 0.0 2.8e-23 83.4 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEG08570.1 - 1.4e-16 60.1 0.0 3e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KEG08570.1 - 2.5e-09 37.6 0.0 2e-08 34.6 0.0 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KEG08570.1 - 8.1e-07 28.4 0.0 1.9e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KEG08570.1 - 4.3e-05 23.2 0.5 7.4e-05 22.4 0.3 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Kinesin PF00225.18 KEG08571.1 - 8.7e-72 241.6 0.0 4e-41 140.8 0.0 3.1 3 0 0 3 3 3 2 Kinesin motor domain AAA_23 PF13476.1 KEG08571.1 - 1.4 9.2 5.1 24 5.1 3.0 2.3 2 0 0 2 2 2 0 AAA domain ArfGap PF01412.13 KEG08573.1 - 4.1e-29 100.7 0.5 7.6e-29 99.8 0.4 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF2917 PF11142.3 KEG08575.1 - 0.017 14.2 0.1 0.54 9.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2917) DAGK_acc PF00609.14 KEG08577.1 - 2.8e-28 99.0 0.0 8.1e-27 94.3 0.0 2.7 2 1 0 2 2 2 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 KEG08577.1 - 2.1e-09 36.9 0.1 5.3e-08 32.3 0.0 2.5 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain Pyr_redox_2 PF07992.9 KEG08579.1 - 5.3e-05 23.1 0.0 0.00012 22.0 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEG08579.1 - 0.009 16.0 0.0 5.3 7.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thioredoxin PF00085.15 KEG08580.1 - 4e-53 177.4 0.0 1.1e-26 92.5 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 KEG08580.1 - 1.8e-17 63.5 0.1 1e-07 32.1 0.0 3.5 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KEG08580.1 - 1.1e-14 54.2 0.0 3.6e-06 26.8 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 KEG08580.1 - 1.1e-11 44.7 0.1 0.00021 21.3 0.0 4.0 3 2 2 5 5 4 3 Thioredoxin-like ERp29 PF07749.7 KEG08580.1 - 2.3e-11 44.1 0.0 4e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Redoxin PF08534.5 KEG08580.1 - 8.6e-08 31.8 0.0 0.0005 19.6 0.0 2.4 2 0 0 2 2 2 2 Redoxin Thioredoxin_9 PF14595.1 KEG08580.1 - 3.4e-07 29.8 0.0 0.0019 17.7 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin AhpC-TSA PF00578.16 KEG08580.1 - 7.9e-07 28.8 0.0 0.023 14.3 0.0 2.3 2 0 0 2 2 2 2 AhpC/TSA family ERp29_N PF07912.8 KEG08580.1 - 9.9e-06 25.4 0.0 0.016 15.1 0.0 2.4 2 1 0 2 2 2 2 ERp29, N-terminal domain Thioredoxin_6 PF13848.1 KEG08580.1 - 5.7e-05 23.0 0.0 0.00025 20.9 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Glutaredoxin PF00462.19 KEG08580.1 - 0.0017 18.3 0.0 0.33 10.9 0.0 2.5 2 0 0 2 2 2 1 Glutaredoxin HyaE PF07449.6 KEG08580.1 - 0.0026 17.6 0.0 2.8 7.8 0.0 2.8 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE Thioredoxin_4 PF13462.1 KEG08580.1 - 0.009 16.0 0.0 3.2 7.7 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin tRNA_synt_1c_R1 PF04558.10 KEG08580.1 - 0.046 13.2 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Thioredoxin_5 PF13743.1 KEG08580.1 - 0.11 12.0 0.0 22 4.5 0.0 3.4 3 1 1 4 4 4 0 Thioredoxin Tautomerase PF01361.16 KEG08580.1 - 0.12 12.0 0.3 0.28 10.8 0.2 1.6 1 0 0 1 1 1 0 Tautomerase enzyme Mu-like_Com PF10122.4 KEG08580.1 - 0.3 10.1 2.3 10 5.2 0.1 2.5 2 0 0 2 2 2 0 Mu-like prophage protein Com Thioredoxin PF00085.15 KEG08581.1 - 5.7e-23 80.5 0.0 6.8e-23 80.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 KEG08581.1 - 1.9e-06 27.8 0.0 3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KEG08581.1 - 1.8e-05 24.8 0.1 0.00015 21.9 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KEG08581.1 - 3.6e-05 23.8 0.1 0.0014 18.7 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like TraF PF13728.1 KEG08581.1 - 0.00046 19.7 0.0 0.00073 19.0 0.0 1.4 1 1 0 1 1 1 1 F plasmid transfer operon protein Redoxin PF08534.5 KEG08581.1 - 0.05 13.1 0.0 0.063 12.8 0.0 1.2 1 0 0 1 1 1 0 Redoxin AhpC-TSA PF00578.16 KEG08581.1 - 0.059 13.0 0.2 0.11 12.1 0.1 1.5 1 1 0 1 1 1 0 AhpC/TSA family ERp29_N PF07912.8 KEG08581.1 - 0.14 12.0 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 ERp29, N-terminal domain DUF2012 PF09430.5 KEG08582.1 - 9.7e-32 109.3 0.0 1.4e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.1 KEG08582.1 - 0.00014 21.8 0.4 0.00036 20.5 0.3 1.6 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain SNARE PF05739.14 KEG08583.1 - 2.1e-10 40.1 0.8 2.6e-10 39.8 0.5 1.1 1 0 0 1 1 1 1 SNARE domain Methyltransf_PK PF05891.7 KEG08583.1 - 0.09 12.0 0.1 0.099 11.9 0.0 1.1 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase SlyX PF04102.7 KEG08583.1 - 0.098 13.0 0.1 0.19 12.1 0.1 1.5 1 1 0 1 1 1 0 SlyX TBCA PF02970.11 KEG08583.1 - 0.13 12.3 0.1 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Tubulin binding cofactor A ODV-E18 PF10717.4 KEG08583.1 - 0.23 10.8 1.5 0.35 10.3 1.1 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 BLOC1_2 PF10046.4 KEG08584.1 - 0.00044 20.3 1.5 0.00061 19.8 1.0 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 VPS11_C PF12451.3 KEG08584.1 - 0.012 15.4 0.3 0.028 14.2 0.2 1.7 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal DUF935 PF06074.7 KEG08584.1 - 0.068 11.8 9.0 0.081 11.6 6.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF935) Uso1_p115_C PF04871.8 KEG08584.1 - 0.19 11.6 10.0 0.23 11.3 6.9 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Ribonuc_P_40 PF08584.6 KEG08584.1 - 0.2 10.6 1.7 0.22 10.4 1.2 1.0 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit DASH_Dad2 PF08654.5 KEG08584.1 - 0.29 11.1 4.7 0.15 12.0 0.3 2.1 1 1 1 2 2 2 0 DASH complex subunit Dad2 T2SF PF00482.18 KEG08584.1 - 0.44 10.4 2.7 0.56 10.1 1.8 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F Synaptobrevin PF00957.16 KEG08584.1 - 0.82 9.3 3.2 1.1 8.8 2.0 1.5 1 1 0 1 1 1 0 Synaptobrevin Hom_end_hint PF05203.11 KEG08584.1 - 0.83 9.3 4.2 0.91 9.2 2.9 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint TipAS PF07739.8 KEG08584.1 - 0.97 9.7 9.9 1.7 8.9 6.9 1.5 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain Fib_alpha PF08702.5 KEG08584.1 - 1.1 9.3 5.7 1.2 9.1 4.0 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family AAA_13 PF13166.1 KEG08584.1 - 1.3 7.4 5.8 1.3 7.4 4.0 1.0 1 0 0 1 1 1 0 AAA domain Mnd1 PF03962.10 KEG08584.1 - 1.4 8.5 14.1 1.8 8.2 9.8 1.2 1 0 0 1 1 1 0 Mnd1 family DUF2570 PF10828.3 KEG08584.1 - 2.2 7.9 8.6 3.3 7.3 5.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) DIRP PF06584.8 KEG08584.1 - 2.7 7.8 7.8 3 7.7 5.4 1.1 1 0 0 1 1 1 0 DIRP Filament PF00038.16 KEG08584.1 - 3.3 7.1 16.2 4 6.8 11.2 1.0 1 0 0 1 1 1 0 Intermediate filament protein ERM PF00769.14 KEG08584.1 - 3.3 7.1 22.1 3.6 7.0 15.3 1.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family V_ATPase_I PF01496.14 KEG08584.1 - 5.3 4.7 9.0 5.4 4.7 6.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3584 PF12128.3 KEG08584.1 - 6.4 3.9 17.7 7.2 3.7 12.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GBP_C PF02841.9 KEG08584.1 - 6.6 5.8 15.0 8.1 5.5 10.4 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain MerR-DNA-bind PF09278.6 KEG08584.1 - 6.6 7.2 17.3 7.2 7.0 2.6 3.0 1 1 2 3 3 3 0 MerR, DNA binding DUF4192 PF13830.1 KEG08584.1 - 7 6.2 12.3 8 6.0 8.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) CENP-H PF05837.7 KEG08584.1 - 7.4 6.8 10.3 6.2 7.0 6.5 1.4 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Ribosomal_60s PF00428.14 KEG08586.1 - 0.0059 16.9 1.0 0.01 16.2 0.7 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3682 PF12446.3 KEG08586.1 - 0.012 15.9 2.8 0.017 15.3 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) DUF4129 PF13559.1 KEG08586.1 - 0.14 12.1 1.9 0.18 11.7 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4129) Pkinase PF00069.20 KEG08588.1 - 4.1e-48 163.7 0.0 5.6e-48 163.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG08588.1 - 5.7e-16 58.3 0.0 7.7e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEG08588.1 - 0.0016 18.2 0.2 0.58 9.8 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family AAA PF00004.24 KEG08590.1 - 1.1e-31 109.7 0.0 1.7e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEG08590.1 - 6.3e-08 32.8 0.1 1.1e-05 25.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEG08590.1 - 1.1e-05 25.4 0.3 2.9e-05 24.1 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KEG08590.1 - 1.7e-05 25.6 0.3 4.6e-05 24.2 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.1 KEG08590.1 - 2.3e-05 24.6 0.0 3.8e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KEG08590.1 - 2.8e-05 23.6 1.1 0.0056 16.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 KEG08590.1 - 3.1e-05 23.6 0.1 0.00015 21.4 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 KEG08590.1 - 0.00023 21.0 0.1 0.00074 19.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KEG08590.1 - 0.00036 20.2 0.1 0.0011 18.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KEG08590.1 - 0.0015 18.0 0.1 0.0067 15.8 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein RNA_helicase PF00910.17 KEG08590.1 - 0.0023 18.0 0.0 0.0065 16.6 0.0 1.8 1 0 0 1 1 1 1 RNA helicase Rad17 PF03215.10 KEG08590.1 - 0.0029 16.3 0.0 0.0044 15.7 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_24 PF13479.1 KEG08590.1 - 0.0049 16.4 0.1 0.011 15.3 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_11 PF13086.1 KEG08590.1 - 0.0059 16.2 0.0 0.0084 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KEG08590.1 - 0.007 16.0 0.1 0.015 14.9 0.1 1.7 1 1 0 1 1 1 1 NACHT domain Sigma54_activ_2 PF14532.1 KEG08590.1 - 0.0072 16.3 0.0 0.021 14.8 0.0 1.8 1 1 1 2 2 2 1 Sigma-54 interaction domain UPF0079 PF02367.12 KEG08590.1 - 0.0084 15.7 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 RuvB_N PF05496.7 KEG08590.1 - 0.009 15.0 0.0 0.02 13.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 KEG08590.1 - 0.016 15.1 0.2 0.038 13.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.8 KEG08590.1 - 0.02 13.8 0.1 0.11 11.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 KEG08590.1 - 0.031 14.1 0.0 0.078 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KEG08590.1 - 0.037 14.3 0.0 0.063 13.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.16 KEG08590.1 - 0.052 12.6 0.0 0.091 11.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 KEG08590.1 - 0.072 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 KEG08590.1 - 0.09 12.3 0.1 0.27 10.8 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 KEG08590.1 - 0.094 11.4 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Arch_ATPase PF01637.13 KEG08590.1 - 0.11 12.1 0.1 5.2 6.6 0.0 2.2 1 1 1 2 2 2 0 Archaeal ATPase Viral_helicase1 PF01443.13 KEG08590.1 - 0.15 11.5 0.3 0.33 10.4 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Topoisom_bac PF01131.15 KEG08591.1 - 1.1e-95 320.8 0.0 1.4e-95 320.5 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 KEG08591.1 - 2.3e-14 53.1 0.0 4.4e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Toprim domain zf-BED PF02892.10 KEG08591.1 - 0.034 13.8 3.0 2.5 7.9 0.1 3.3 3 0 0 3 3 3 0 BED zinc finger Ssu72 PF04722.8 KEG08591.1 - 0.035 13.3 0.0 0.06 12.6 0.0 1.3 1 0 0 1 1 1 0 Ssu72-like protein Erv26 PF04148.8 KEG08593.1 - 2.5e-23 82.5 7.6 3.8e-23 81.9 5.3 1.2 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF3112 PF11309.3 KEG08593.1 - 2.2 8.0 8.1 3.3 7.4 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) Aminotran_4 PF01063.14 KEG08594.1 - 7.2e-28 97.6 0.0 9.5e-28 97.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Mito_carr PF00153.22 KEG08595.1 - 2.6e-31 107.1 1.0 2.2e-14 52.9 0.2 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S30 PF04758.9 KEG08595.1 - 0.36 10.6 2.5 0.79 9.5 0.2 2.6 3 0 0 3 3 3 0 Ribosomal protein S30 ubiquitin PF00240.18 KEG08596.1 - 0.0078 15.5 0.0 0.037 13.4 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 KEG08596.1 - 0.062 13.0 0.0 0.25 11.0 0.0 2.1 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like GMP_PDE_delta PF05351.6 KEG08597.1 - 6.3e-61 204.7 0.8 7.5e-61 204.5 0.5 1.1 1 0 0 1 1 1 1 GMP-PDE, delta subunit Pterin_4a PF01329.14 KEG08600.1 - 3.8e-09 36.1 0.0 9.3e-08 31.7 0.0 2.1 2 0 0 2 2 2 1 Pterin 4 alpha carbinolamine dehydratase HrpB_C PF08482.5 KEG08600.1 - 0.022 14.8 0.0 0.04 14.0 0.0 1.3 1 0 0 1 1 1 0 ATP-dependent helicase C-terminal COPI_assoc PF08507.5 KEG08601.1 - 4.1e-09 36.2 4.9 4.8e-09 36.0 3.4 1.2 1 0 0 1 1 1 1 COPI associated protein Cytochrom_B558a PF05038.8 KEG08601.1 - 2.6 7.6 4.3 2.4 7.7 0.7 2.1 1 1 1 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit TNV_CP PF03898.8 KEG08603.1 - 0.011 14.7 0.1 0.021 13.9 0.0 1.5 1 1 0 1 1 1 0 Satellite tobacco necrosis virus coat protein PAT1 PF09770.4 KEG08605.1 - 0.33 9.1 18.5 0.33 9.1 12.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Lin-8 PF03353.10 KEG08605.1 - 1.2 8.3 6.9 1.3 8.1 4.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist OAD_gamma PF04277.8 KEG08605.1 - 3.5 8.0 6.9 0.57 10.5 0.6 2.0 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain CDK5_activator PF03261.10 KEG08605.1 - 4 6.6 9.2 5.1 6.3 6.4 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Hid1 PF12722.2 KEG08605.1 - 4.2 4.9 7.0 4.8 4.7 4.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein dCMP_cyt_deam_1 PF00383.17 KEG08606.1 - 1.2e-12 47.3 1.8 2.4e-11 43.1 1.2 2.2 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 KEG08606.1 - 0.68 9.7 8.7 0.21 11.4 2.3 2.6 1 1 1 2 2 2 0 Bd3614-like deaminase YqjK PF13997.1 KEG08608.1 - 0.18 11.9 0.8 0.33 11.1 0.0 1.8 2 0 0 2 2 2 0 YqjK-like protein PC-Esterase PF13839.1 KEG08609.1 - 0.012 15.3 0.6 0.019 14.7 0.2 1.5 2 0 0 2 2 2 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p His_Phos_1 PF00300.17 KEG08610.1 - 8.5e-30 103.9 0.0 1.1e-29 103.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_1 PF00300.17 KEG08611.1 - 8.3e-17 61.7 0.0 1.2e-16 61.2 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) zf-HIT PF04438.11 KEG08612.1 - 3e-07 29.9 11.4 4.8e-07 29.3 7.9 1.4 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.13 KEG08612.1 - 0.019 14.7 13.7 0.037 13.9 9.5 1.5 1 0 0 1 1 1 0 MYND finger 5_3_exonuc_N PF02739.11 KEG08612.1 - 0.1 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain DUF1639 PF07797.9 KEG08614.1 - 0.4 10.1 0.0 0.4 10.1 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1639) DnaJ PF00226.26 KEG08615.1 - 3.4e-17 61.9 0.3 3.4e-17 61.9 0.2 1.9 2 0 0 2 2 2 1 DnaJ domain RNase_H2-Ydr279 PF09468.5 KEG08615.1 - 0.26 10.4 3.1 0.4 9.8 2.1 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Tom37_C PF11801.3 KEG08615.1 - 1.5 8.6 6.5 2.3 8.0 4.5 1.4 1 0 0 1 1 1 0 Tom37 C-terminal domain PLRV_ORF5 PF01690.12 KEG08615.1 - 2.1 7.3 6.6 2.5 7.1 4.6 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein UPF0561 PF10573.4 KEG08615.1 - 2.7 7.8 7.3 5.3 6.8 5.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 Spore_coat_CotO PF14153.1 KEG08615.1 - 3.2 7.1 11.2 5.4 6.4 7.7 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Ycf1 PF05758.7 KEG08615.1 - 3.4 5.2 6.4 4 5.0 4.4 1.0 1 0 0 1 1 1 0 Ycf1 FUSC PF04632.7 KEG08615.1 - 3.8 5.8 10.1 4.5 5.5 7.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family PV-1 PF06637.6 KEG08615.1 - 5.1 5.5 13.5 6.7 5.1 9.4 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) MCM PF00493.18 KEG08616.1 - 6.8e-108 360.3 0.0 1e-107 359.8 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KEG08616.1 - 2.1e-16 60.5 0.0 4.8e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KEG08616.1 - 6.3e-09 35.2 0.1 1.7e-07 30.6 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KEG08616.1 - 2.7e-05 23.7 0.0 0.00026 20.4 0.0 2.1 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.6 KEG08616.1 - 0.00012 21.6 0.0 0.00037 20.0 0.0 1.8 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KEG08616.1 - 0.0039 16.9 0.0 0.013 15.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Complex1_LYR PF05347.10 KEG08617.1 - 3.7e-09 36.2 0.6 6.6e-09 35.4 0.4 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KEG08617.1 - 1e-05 25.6 1.2 2e-05 24.7 0.8 1.5 1 0 0 1 1 1 1 Complex1_LYR-like ketoacyl-synt PF00109.21 KEG08618.1 - 8.3e-10 38.5 0.1 1.7e-09 37.5 0.1 1.5 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KEG08619.1 - 1.3e-27 96.0 0.1 1.7e-27 95.6 0.1 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.21 KEG08619.1 - 1.2e-05 24.9 0.0 2.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain RRM_6 PF14259.1 KEG08620.1 - 3.5e-21 74.9 0.1 2.4e-14 53.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEG08620.1 - 3.5e-19 68.1 0.0 1e-10 41.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG08620.1 - 4e-07 29.7 0.0 0.0022 17.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) APC_CDC26 PF10471.4 KEG08621.1 - 0.034 14.8 4.0 0.044 14.5 2.8 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 DUF1631 PF07793.6 KEG08621.1 - 0.079 11.0 1.6 0.081 11.0 1.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) TSA PF03249.8 KEG08621.1 - 0.87 8.0 7.4 1 7.8 5.1 1.2 1 0 0 1 1 1 0 Type specific antigen Pro_isomerase PF00160.16 KEG08622.1 - 3.1e-31 108.6 0.0 4.8e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF221 PF02714.10 KEG08623.1 - 1.4e-37 129.3 5.4 1.4e-37 129.3 3.7 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF221 Adap_comp_sub PF00928.16 KEG08624.1 - 5.2e-15 55.2 0.0 7.9e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KEG08624.1 - 2.5e-07 30.5 0.2 4.1e-07 29.8 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Reo_sigmaC PF04582.7 KEG08625.1 - 0.00094 18.4 22.3 0.16 11.0 0.4 5.3 5 0 0 5 5 5 4 Reovirus sigma C capsid protein NTP_transf_4 PF13562.1 KEG08626.1 - 0.0074 15.9 1.6 0.088 12.4 0.3 2.7 2 1 0 2 2 2 1 Sugar nucleotidyl transferase DivIC PF04977.10 KEG08626.1 - 0.16 11.5 20.4 0.58 9.6 0.7 4.8 4 1 1 5 5 5 0 Septum formation initiator bZIP_1 PF00170.16 KEG08626.1 - 0.32 10.9 18.4 0.66 9.9 0.1 4.3 5 0 0 5 5 5 0 bZIP transcription factor FliJ PF02050.11 KEG08626.1 - 1.2 9.2 23.4 2.6 8.1 1.4 4.6 3 1 2 5 5 5 0 Flagellar FliJ protein DUF904 PF06005.7 KEG08626.1 - 1.6 9.0 24.2 11 6.4 2.3 5.1 5 0 0 5 5 5 0 Protein of unknown function (DUF904) GAS PF13851.1 KEG08626.1 - 8.7 5.4 22.4 0.17 11.0 5.8 3.5 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding C2 PF00168.25 KEG08627.1 - 0.004 16.9 0.0 0.0091 15.8 0.0 1.7 1 0 0 1 1 1 1 C2 domain Cytochrom_C_2 PF01322.15 KEG08627.1 - 0.023 15.2 6.2 0.53 10.8 0.0 3.7 3 0 0 3 3 3 0 Cytochrome C' Reo_sigmaC PF04582.7 KEG08627.1 - 0.027 13.6 1.4 0.32 10.1 0.1 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DivIVA PF05103.8 KEG08627.1 - 1.8 8.6 34.9 1 9.4 0.6 5.4 3 1 2 5 5 5 0 DivIVA protein BAF1_ABF1 PF04684.8 KEG08628.1 - 0.47 9.2 14.9 1.1 8.0 10.3 1.5 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DnaJ PF00226.26 KEG08629.1 - 3e-17 62.0 0.0 7.3e-17 60.8 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain zf-C3HC4_3 PF13920.1 KEG08629.1 - 0.0012 18.5 6.6 0.002 17.7 4.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Peptidase_S64 PF08192.6 KEG08629.1 - 0.3 9.3 11.8 0.052 11.8 5.7 1.4 1 1 0 1 1 1 0 Peptidase family S64 Hamartin PF04388.7 KEG08629.1 - 1.2 7.7 9.8 1.5 7.3 6.8 1.1 1 0 0 1 1 1 0 Hamartin protein RNB PF00773.14 KEG08632.1 - 9.8e-92 307.6 0.5 1.6e-91 307.0 0.4 1.2 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 KEG08632.1 - 3e-06 27.3 0.2 7.6e-06 26.0 0.1 1.7 1 0 0 1 1 1 1 PIN domain Endonuclease_NS PF01223.18 KEG08634.1 - 2.1e-55 187.5 0.2 3.6e-55 186.8 0.0 1.4 2 0 0 2 2 2 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.1 KEG08634.1 - 0.005 16.8 1.7 0.018 15.0 1.2 1.8 1 1 0 1 1 1 1 DNA/RNA non-specific endonuclease ABC1 PF03109.11 KEG08635.1 - 7.3e-24 84.0 0.0 1.6e-23 82.9 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 KEG08635.1 - 0.054 13.2 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 KEG08635.1 - 0.077 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family CAF1A PF12253.3 KEG08637.1 - 0.0012 18.9 17.1 0.0012 18.9 11.9 5.1 4 1 0 4 4 4 1 Chromatin assembly factor 1 subunit A ADH_zinc_N PF00107.21 KEG08638.1 - 1.9e-17 63.0 0.7 3.7e-17 62.0 0.5 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEG08638.1 - 5.3e-14 53.1 0.1 1.3e-13 51.9 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEG08638.1 - 2.2e-06 27.3 0.0 1.1e-05 25.1 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF1664 PF07889.7 KEG08639.1 - 0.0036 17.0 3.5 0.0036 17.0 2.4 3.2 2 1 2 4 4 4 1 Protein of unknown function (DUF1664) Ribosomal_60s PF00428.14 KEG08639.1 - 0.74 10.2 20.2 0.073 13.4 7.1 3.2 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF342 PF03961.8 KEG08639.1 - 1.1 7.6 16.4 0.087 11.2 1.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF342) OmpH PF03938.9 KEG08639.1 - 9.1 6.1 23.3 1.5e+04 -4.8 16.2 2.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) PseudoU_synth_1 PF01416.15 KEG08640.1 - 5.8e-11 42.7 0.0 3.6e-08 33.7 0.0 3.5 3 1 0 3 3 3 2 tRNA pseudouridine synthase RNA_pol_L PF01193.19 KEG08640.1 - 0.067 12.3 0.0 0.42 9.7 0.0 2.3 3 0 0 3 3 3 0 RNA polymerase Rpb3/Rpb11 dimerisation domain WD40 PF00400.27 KEG08641.1 - 2.3e-24 84.2 8.0 3.1e-07 30.0 0.5 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 KEG08641.1 - 0.018 14.7 0.0 1.3 8.7 0.0 2.9 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Trypan_PARP PF05887.6 KEG08644.1 - 0.22 11.3 3.2 0.32 10.8 2.2 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SCO1-SenC PF02630.9 KEG08645.1 - 4.9e-46 156.5 0.0 6.8e-46 156.0 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 KEG08645.1 - 0.00072 19.2 0.0 0.0021 17.7 0.0 1.8 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_8 PF13905.1 KEG08645.1 - 0.0032 17.5 0.0 0.0063 16.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like TIR_2 PF13676.1 KEG08645.1 - 0.1 12.7 0.0 1.7 8.8 0.0 2.5 2 0 0 2 2 2 0 TIR domain Milton PF12448.3 KEG08646.1 - 2.3 8.3 5.5 0.65 10.1 0.1 2.5 2 0 0 2 2 2 0 Kinesin associated protein CPSase_L_D2 PF02786.12 KEG08647.1 - 4.6e-103 343.0 0.6 3.3e-78 261.8 0.1 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 KEG08647.1 - 8.9e-46 154.6 0.0 1.9e-45 153.5 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 KEG08647.1 - 2.7e-43 147.6 0.0 6.5e-43 146.4 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.14 KEG08647.1 - 6.2e-37 126.1 0.1 1.6e-36 124.7 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 KEG08647.1 - 1.5e-35 122.6 0.9 2e-22 79.8 0.1 2.6 2 0 0 2 2 2 2 ATP-grasp domain CPSase_L_chain PF00289.17 KEG08647.1 - 6.3e-35 119.6 0.0 8.4e-19 67.7 0.0 2.9 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 KEG08647.1 - 4.6e-22 78.2 0.1 1.3e-16 60.3 0.0 3.4 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KEG08647.1 - 2.2e-21 75.9 0.4 2.8e-11 43.0 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Arginosuc_synth PF00764.14 KEG08647.1 - 1.9e-15 56.8 0.0 1.5e-14 53.8 0.0 2.2 2 0 0 2 2 2 1 Arginosuccinate synthase MGS PF02142.17 KEG08647.1 - 2.7e-14 52.8 0.0 1.2e-13 50.8 0.0 2.3 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.8 KEG08647.1 - 2.8e-13 49.7 0.3 1.9e-05 24.1 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus Peptidase_C26 PF07722.8 KEG08647.1 - 1e-06 28.3 0.4 1.8e-05 24.3 0.3 2.5 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 KEG08647.1 - 0.00015 21.6 0.1 0.01 15.7 0.0 2.7 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.6 KEG08647.1 - 0.0012 18.3 0.0 0.086 12.3 0.0 3.0 2 1 0 2 2 2 1 RimK-like ATP-grasp domain DJ-1_PfpI PF01965.19 KEG08647.1 - 0.007 15.8 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family GSH-S_ATP PF02955.11 KEG08647.1 - 0.046 12.8 0.0 0.14 11.3 0.0 1.8 2 0 0 2 2 2 0 Prokaryotic glutathione synthetase, ATP-grasp domain HEM4 PF02602.10 KEG08647.1 - 0.1 11.8 0.0 0.46 9.6 0.0 2.2 2 0 0 2 2 2 0 Uroporphyrinogen-III synthase HemD Amidohydro_4 PF13147.1 KEG08648.1 - 2.7e-20 73.5 10.8 7.6e-20 72.0 7.5 1.7 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KEG08648.1 - 2.2e-06 27.5 1.6 4e-06 26.7 1.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.9 KEG08648.1 - 0.00016 21.3 9.3 0.0016 18.0 6.4 2.2 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KEG08648.1 - 0.0019 17.9 0.5 0.0071 16.1 0.1 2.1 2 0 0 2 2 2 1 Amidohydrolase DHOase PF12890.2 KEG08648.1 - 0.095 12.3 0.0 2.8 7.6 0.0 2.6 1 1 0 1 1 1 0 Dihydro-orotase-like AP_endonuc_2 PF01261.19 KEG08648.1 - 0.11 11.7 2.7 0.31 10.3 1.2 2.2 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel zf-NADH-PPase PF09297.6 KEG08648.1 - 5.8 6.5 6.8 27 4.4 0.6 3.5 4 0 0 4 4 4 0 NADH pyrophosphatase zinc ribbon domain OMPdecase PF00215.19 KEG08649.1 - 1.7e-32 112.6 0.0 1.9e-32 112.5 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Phage_Coat_Gp8 PF05371.7 KEG08649.1 - 0.023 14.2 0.6 0.058 12.9 0.4 1.7 1 0 0 1 1 1 0 Phage major coat protein, Gp8 Amastin PF07344.6 KEG08650.1 - 4.2e-34 117.4 15.9 5.2e-34 117.0 11.0 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein PMP22_Claudin PF00822.15 KEG08650.1 - 0.00054 19.6 13.8 0.00078 19.1 9.5 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Cation_ATPase_C PF00689.16 KEG08650.1 - 0.37 10.2 15.4 0.62 9.5 10.6 1.3 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus Claudin_2 PF13903.1 KEG08650.1 - 1.5 8.5 20.2 2.3 7.8 13.8 1.5 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 KEG08651.1 - 5.4e-26 91.0 7.9 6.9e-26 90.7 5.5 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Nucleoporin_C PF03177.9 KEG08652.1 - 0.0046 15.5 0.1 0.0067 15.0 0.1 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal PHD PF00628.24 KEG08653.1 - 5.6e-07 29.1 9.3 1.2e-06 28.0 6.4 1.6 1 0 0 1 1 1 1 PHD-finger Acetyltransf_1 PF00583.19 KEG08653.1 - 9.1e-05 22.4 0.2 0.0031 17.4 0.1 2.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KEG08653.1 - 0.0082 16.2 2.4 0.028 14.5 0.1 2.8 3 1 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KEG08653.1 - 0.018 15.2 0.0 0.045 13.9 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TPR_2 PF07719.12 KEG08654.1 - 0.00041 20.0 0.4 0.61 10.1 0.2 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat Glyco_transf_18 PF15024.1 KEG08654.1 - 0.00076 17.9 0.4 0.00099 17.5 0.3 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 18 PI3_PI4_kinase PF00454.22 KEG08654.1 - 0.00078 18.9 0.0 0.004 16.6 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase Glyco_transf_8 PF01501.15 KEG08654.1 - 0.0011 18.3 0.0 0.0019 17.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 TPR_1 PF00515.23 KEG08654.1 - 0.0016 17.9 0.4 1.8 8.2 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEG08654.1 - 0.028 14.3 0.6 5.1 7.1 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1193 PF06702.7 KEG08654.1 - 0.047 13.0 0.1 0.3 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1193) 3HCDH PF00725.17 KEG08655.1 - 1.5e-08 34.9 0.1 0.00014 22.2 0.0 3.0 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH PF00378.15 KEG08655.1 - 2.2e-05 23.6 0.0 5.6e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Mito_fiss_reg PF05308.6 KEG08655.1 - 0.017 14.5 6.9 0.04 13.2 4.8 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 KEG08655.1 - 0.85 8.8 9.1 1.4 8.1 6.3 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Drc1-Sld2 PF11719.3 KEG08656.1 - 2.1e-08 33.6 0.2 0.0045 16.1 0.0 2.1 2 0 0 2 2 2 2 DNA replication and checkpoint protein HrpB4 PF09502.5 KEG08656.1 - 0.03 13.5 0.2 0.059 12.5 0.1 1.4 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB4) DUF1451 PF07295.6 KEG08656.1 - 0.063 13.0 0.6 2.2 8.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1451) Ank_2 PF12796.2 KEG08657.1 - 7.9e-15 54.9 0.0 6.5e-06 26.4 0.0 2.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KEG08657.1 - 4.2e-09 35.7 0.0 0.0029 17.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KEG08657.1 - 2e-07 31.0 0.0 9.2e-05 22.5 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEG08657.1 - 1.2e-06 28.2 0.0 0.054 13.7 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KEG08657.1 - 3.8e-06 27.2 0.0 0.034 14.6 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Aminotran_1_2 PF00155.16 KEG08658.1 - 2.5e-50 171.4 0.0 3e-50 171.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KEG08658.1 - 2.4e-05 23.5 0.0 4.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 KEG08658.1 - 0.0039 16.3 0.0 0.0058 15.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KEG08658.1 - 0.014 14.1 0.0 0.027 13.2 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V Aminotran_3 PF00202.16 KEG08658.1 - 0.014 14.2 0.0 0.022 13.5 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-III DUF4608 PF15381.1 KEG08658.1 - 0.096 12.8 0.0 1.5 9.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4608) DUF605 PF04652.11 KEG08659.1 - 0.2 11.0 48.6 0.26 10.6 33.7 1.0 1 0 0 1 1 1 0 Vta1 like DUF59 PF01883.14 KEG08660.1 - 1.6e-08 34.4 0.0 3.7e-08 33.2 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function DUF59 RRM_1 PF00076.17 KEG08661.1 - 1e-09 37.8 0.3 0.0024 17.4 0.0 4.3 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG08661.1 - 1.4e-05 24.9 1.0 0.35 10.8 0.0 3.8 4 0 0 4 4 4 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PAM2 PF07145.10 KEG08661.1 - 0.0035 16.7 0.1 0.01 15.2 0.1 1.9 1 0 0 1 1 1 1 Ataxin-2 C-terminal region RRM_5 PF13893.1 KEG08661.1 - 0.032 14.0 1.1 5.4 6.9 0.1 3.7 4 1 0 4 4 4 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_M29 PF02073.10 KEG08661.1 - 0.19 10.4 0.5 0.32 9.7 0.4 1.2 1 0 0 1 1 1 0 Thermophilic metalloprotease (M29) HpaP PF09483.5 KEG08663.1 - 0.17 11.8 4.3 0.21 11.5 3.0 1.1 1 0 0 1 1 1 0 Type III secretion protein (HpaP) Prefoldin_2 PF01920.15 KEG08666.1 - 4.3e-17 61.8 3.8 4.3e-17 61.8 2.6 2.2 1 1 1 2 2 2 1 Prefoldin subunit DUF948 PF06103.6 KEG08666.1 - 0.3 10.9 4.9 5.6 6.8 0.9 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) GAS PF13851.1 KEG08666.1 - 2.1 7.5 16.9 0.073 12.2 1.1 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 KEG08666.1 - 9 5.8 16.9 15 5.1 11.7 1.4 1 1 0 1 1 1 0 IncA protein LRR_4 PF12799.2 KEG08667.1 - 4.7e-36 121.8 13.3 2.4e-08 33.4 0.1 6.5 4 1 3 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG08667.1 - 1.4e-19 69.5 15.8 1.9e-07 30.6 0.6 6.1 5 2 2 7 7 7 6 Leucine rich repeat LRR_1 PF00560.28 KEG08667.1 - 1.2e-15 55.1 16.1 0.18 11.9 0.1 10.2 10 0 0 10 10 10 4 Leucine Rich Repeat LRR_9 PF14580.1 KEG08667.1 - 1.8e-12 47.1 6.7 0.0027 17.2 0.0 4.9 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.1 KEG08667.1 - 5.1e-11 41.4 7.5 0.3 11.3 0.0 9.3 7 3 3 10 10 10 1 Leucine Rich repeat LRR_7 PF13504.1 KEG08667.1 - 6.1e-10 37.6 8.0 0.47 10.8 0.0 8.7 9 0 0 9 9 9 1 Leucine rich repeat DUF310 PF03750.8 KEG08667.1 - 0.07 13.3 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF310) PsiA PF06952.6 KEG08668.1 - 7 5.6 10.8 15 4.5 7.3 1.6 1 1 1 2 2 2 0 PsiA protein Peptidase_M17 PF00883.16 KEG08670.1 - 1.8e-98 329.2 0.0 2.4e-98 328.8 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 KEG08670.1 - 1.1e-09 38.0 0.4 6.7e-09 35.5 0.1 2.2 2 0 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain CHB_HEX_C PF03174.8 KEG08671.1 - 2.1e-10 40.2 0.0 2.1e-06 27.4 0.1 3.9 3 1 0 3 3 3 2 Chitobiase/beta-hexosaminidase C-terminal domain CHB_HEX_C_1 PF13290.1 KEG08671.1 - 1.2e-08 34.6 3.1 1.7e-05 24.4 0.1 3.5 2 1 0 2 2 2 2 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.1 KEG08671.1 - 3.8e-07 30.1 3.7 0.00024 21.1 0.0 3.2 2 1 0 2 2 2 2 Fn3 associated TerB PF05099.8 KEG08672.1 - 0.00015 21.4 0.1 0.0003 20.5 0.1 1.5 1 0 0 1 1 1 1 Tellurite resistance protein TerB WXG100 PF06013.7 KEG08673.1 - 2.3 8.2 5.7 24 5.0 0.0 3.0 3 0 0 3 3 3 0 Proteins of 100 residues with WXG EMI PF07546.8 KEG08675.1 - 2.8 8.4 6.0 0.3 11.5 1.4 1.5 2 0 0 2 2 2 0 EMI domain Fringe PF02434.11 KEG08677.1 - 7.7e-05 22.0 1.5 0.001 18.3 1.0 2.2 1 1 0 1 1 1 1 Fringe-like CENP-R PF06729.7 KEG08678.1 - 0.02 14.5 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Kinetochore component, CENP-R Prefoldin_2 PF01920.15 KEG08680.1 - 0.066 12.9 0.6 0.077 12.7 0.4 1.1 1 0 0 1 1 1 0 Prefoldin subunit DUF2802 PF10975.3 KEG08680.1 - 1.5 8.6 3.9 3.3 7.5 2.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2802) MAD PF05557.8 KEG08686.1 - 0.0017 16.5 4.1 0.0019 16.4 2.9 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein ASD2 PF08687.6 KEG08686.1 - 0.0043 16.4 4.9 0.0058 16.0 3.4 1.1 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 ATC_hydrolase PF14196.1 KEG08686.1 - 0.011 16.1 3.4 0.015 15.6 2.3 1.3 1 0 0 1 1 1 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase RNF111_N PF15303.1 KEG08686.1 - 0.012 15.2 2.7 0.016 14.7 1.9 1.1 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus Atg14 PF10186.4 KEG08686.1 - 0.045 12.6 8.4 0.063 12.2 5.8 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 EMP24_GP25L PF01105.19 KEG08686.1 - 0.056 13.1 3.5 0.11 12.1 2.5 1.5 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Tho2 PF11262.3 KEG08686.1 - 0.059 12.4 3.8 0.086 11.8 2.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Poty_PP PF08440.5 KEG08686.1 - 0.082 11.9 6.0 0.12 11.3 4.2 1.2 1 0 0 1 1 1 0 Potyviridae polyprotein DUF342 PF03961.8 KEG08686.1 - 0.17 10.2 4.6 0.21 9.9 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF3450 PF11932.3 KEG08686.1 - 0.19 10.9 11.6 0.3 10.3 8.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF972 PF06156.8 KEG08686.1 - 0.33 11.3 7.9 0.16 12.3 3.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF948 PF06103.6 KEG08686.1 - 0.35 10.7 2.4 0.57 10.0 1.6 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) HlyD PF00529.15 KEG08686.1 - 0.57 9.4 12.1 0.76 9.0 8.4 1.1 1 0 0 1 1 1 0 HlyD family secretion protein CHD5 PF04420.9 KEG08686.1 - 1.3 8.6 5.4 2.1 7.9 3.7 1.3 1 0 0 1 1 1 0 CHD5-like protein TMPIT PF07851.8 KEG08686.1 - 2 7.4 6.3 2.7 6.9 4.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein Ax_dynein_light PF10211.4 KEG08686.1 - 2.9 7.6 12.6 0.47 10.2 3.6 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain DUF904 PF06005.7 KEG08686.1 - 6.8 7.0 16.1 11 6.3 5.9 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF904) RRM_1 PF00076.17 KEG08687.1 - 3.9e-14 52.0 0.0 6.3e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG08687.1 - 5.5e-09 35.8 0.0 1.1e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG08687.1 - 0.00057 19.6 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kinesin PF00225.18 KEG08688.1 - 2.9e-83 279.3 1.5 1.9e-82 276.6 0.0 2.7 2 1 0 2 2 2 1 Kinesin motor domain Tubulin PF00091.20 KEG08696.1 - 2.8e-71 239.7 0.0 4.6e-71 239.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KEG08696.1 - 1.8e-47 160.4 0.0 2.8e-47 159.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KEG08696.1 - 2.5e-05 24.3 0.0 5.5e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KEG08696.1 - 0.0024 17.3 0.0 0.0043 16.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.20 KEG08697.1 - 2.2e-67 227.0 0.0 3.1e-67 226.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KEG08697.1 - 4.5e-50 168.9 0.1 7e-50 168.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain DUF1935 PF09149.5 KEG08698.1 - 3.8e-30 103.9 0.0 4.5e-30 103.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF1935 PF09149.5 KEG08700.1 - 9.2e-39 131.6 0.1 1e-38 131.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF1792 PF08759.6 KEG08701.1 - 0.0054 16.3 0.4 0.015 14.9 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1792) HisKA_3 PF07730.8 KEG08701.1 - 0.45 10.8 0.0 0.45 10.8 0.0 4.7 2 1 2 4 4 4 0 Histidine kinase Prominin PF05478.6 KEG08701.1 - 2.9 5.3 6.3 7.1 4.0 4.3 1.8 1 1 0 1 1 1 0 Prominin COG2 PF06148.6 KEG08701.1 - 8 6.3 15.8 2.5 7.9 0.9 3.9 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Mucin PF01456.12 KEG08704.1 - 0.016 14.9 18.1 0.016 14.9 12.5 3.8 3 2 0 3 3 3 0 Mucin-like glycoprotein Mucin PF01456.12 KEG08705.1 - 1.2 8.8 51.7 0.019 14.7 9.9 3.6 1 1 1 3 3 3 0 Mucin-like glycoprotein Apo-CIII PF05778.7 KEG08705.1 - 4.1 6.8 5.9 1.4 8.3 0.3 2.9 3 0 0 3 3 3 0 Apolipoprotein CIII (Apo-CIII) Sec5 PF15469.1 KEG08705.1 - 7.3 6.2 7.1 28 4.3 1.8 2.8 2 1 0 2 2 2 0 Exocyst complex component Sec5 DUF844 PF05815.6 KEG08706.1 - 0.034 12.9 1.6 0.058 12.2 1.1 1.3 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) DUF2009 PF09418.5 KEG08706.1 - 0.1 11.3 7.1 0.053 12.2 3.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2009) IncA PF04156.9 KEG08706.1 - 0.15 11.6 5.1 0.24 10.9 3.4 1.5 1 1 0 1 1 1 0 IncA protein DUF844 PF05815.6 KEG08707.1 - 0.013 14.3 1.3 0.08 11.7 1.1 1.9 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF844) DUF2009 PF09418.5 KEG08707.1 - 0.11 11.2 11.3 0.074 11.8 3.6 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF2009) IncA PF04156.9 KEG08707.1 - 1.6 8.2 10.2 0.55 9.8 3.8 2.1 1 1 1 2 2 2 0 IncA protein DUF3138 PF11336.3 KEG08708.1 - 1 7.4 6.1 0.078 11.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Apolipoprotein PF01442.13 KEG08709.1 - 0.0012 18.4 0.9 0.0012 18.4 0.6 4.0 4 0 0 4 4 4 2 Apolipoprotein A1/A4/E domain DUF1664 PF07889.7 KEG08709.1 - 0.18 11.5 1.0 63 3.3 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) 3HCDH PF00725.17 KEG08710.1 - 0.088 13.2 0.1 0.19 12.1 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain AAA PF00004.24 KEG08711.1 - 7.2e-09 35.9 0.0 4.1e-08 33.5 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KEG08711.1 - 8.7e-07 28.6 0.9 8.7e-07 28.6 0.6 2.4 2 1 0 2 2 1 1 Part of AAA domain AAA_33 PF13671.1 KEG08711.1 - 6.3e-05 22.8 0.4 0.0011 18.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 KEG08711.1 - 6.9e-05 23.6 0.0 0.00019 22.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KEG08711.1 - 8.7e-05 22.6 0.0 0.00031 20.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 KEG08711.1 - 9e-05 21.3 0.0 0.37 9.4 0.0 2.7 3 0 0 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_5 PF07728.9 KEG08711.1 - 0.00014 21.5 0.0 0.00034 20.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KEG08711.1 - 0.00024 20.2 0.0 0.0005 19.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KEG08711.1 - 0.00045 20.2 2.8 0.0023 17.9 0.1 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_25 PF13481.1 KEG08711.1 - 0.00065 19.1 0.0 0.0017 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KEG08711.1 - 0.00074 19.1 3.3 0.0013 18.3 0.3 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KEG08711.1 - 0.00094 19.1 0.1 0.012 15.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KEG08711.1 - 0.0014 18.0 0.0 0.011 15.1 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.1 KEG08711.1 - 0.0033 17.7 0.0 0.0096 16.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 KEG08711.1 - 0.0072 15.5 0.0 0.019 14.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 NACHT PF05729.7 KEG08711.1 - 0.022 14.4 0.0 0.087 12.4 0.0 2.0 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.22 KEG08711.1 - 0.047 13.9 0.0 0.18 12.0 0.0 2.0 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.1 KEG08711.1 - 0.13 11.8 0.2 0.47 10.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KEG08711.1 - 0.19 11.9 0.0 0.47 10.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Kelch_4 PF13418.1 KEG08712.1 - 3.1e-25 87.6 5.4 0.0012 18.5 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 KEG08712.1 - 1.2e-17 63.5 7.7 0.013 15.6 0.1 7.7 7 1 1 8 8 8 5 Galactose oxidase, central domain Kelch_5 PF13854.1 KEG08712.1 - 1.9e-14 53.2 4.9 0.00029 20.6 0.0 5.8 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.1 KEG08712.1 - 6.8e-11 41.8 2.6 0.0026 17.8 0.0 5.5 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 KEG08712.1 - 3.4e-05 23.2 8.0 0.21 11.1 0.1 5.3 6 0 0 6 6 6 2 Kelch motif DUF4113 PF13438.1 KEG08713.1 - 0.11 12.1 1.1 0.22 11.1 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4113) Pkinase PF00069.20 KEG08715.1 - 3.7e-51 173.7 0.0 5.5e-51 173.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG08715.1 - 1.1e-35 122.9 0.0 1.9e-35 122.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG08715.1 - 0.017 14.1 0.0 0.032 13.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KEG08715.1 - 0.086 12.5 0.2 2.4 7.8 0.0 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family SH3_5 PF08460.5 KEG08715.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain Herpes_US9 PF06072.6 KEG08715.1 - 7.4 6.4 7.8 2.7 7.8 0.2 2.8 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Metallophos PF00149.23 KEG08716.1 - 1.7e-10 40.6 0.1 2.5e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KEG08716.1 - 7e-05 22.7 0.0 0.00011 22.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PhoD PF09423.5 KEG08716.1 - 0.0019 16.8 0.0 0.0046 15.5 0.0 1.7 2 0 0 2 2 2 1 PhoD-like phosphatase AAA_4 PF04326.9 KEG08717.1 - 0.0012 18.9 0.0 0.0024 18.0 0.0 1.5 1 0 0 1 1 1 1 Divergent AAA domain ATP-grasp_4 PF13535.1 KEG08720.1 - 2.5e-13 50.1 0.1 6.7e-13 48.7 0.1 1.7 1 1 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KEG08720.1 - 4.4e-12 45.8 0.0 7.2e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus SET PF00856.23 KEG08720.1 - 5.1e-09 36.6 0.1 2.6e-07 31.1 0.1 2.3 1 1 0 1 1 1 1 SET domain ATP-grasp_3 PF02655.9 KEG08720.1 - 5.2e-05 23.1 0.0 0.0001 22.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 KEG08720.1 - 5.5e-05 22.5 0.0 9.2e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KEG08720.1 - 0.0023 16.7 0.1 0.088 11.5 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.14 KEG08720.1 - 0.018 14.6 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 3HCDH PF00725.17 KEG08723.1 - 0.005 17.2 0.1 0.029 14.7 0.0 2.3 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain TPR_7 PF13176.1 KEG08723.1 - 0.1 12.4 4.7 39 4.3 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Metallophos PF00149.23 KEG08724.1 - 1.3e-32 112.8 0.2 1e-31 109.9 0.0 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase ApoL PF05461.6 KEG08725.1 - 0.091 11.9 3.0 0.13 11.5 2.1 1.1 1 0 0 1 1 1 0 Apolipoprotein L FAM183 PF14886.1 KEG08726.1 - 0.0078 16.7 0.2 0.014 15.8 0.2 1.6 1 1 0 1 1 1 1 FAM183A and FAM183B related DUF1053 PF06327.9 KEG08726.1 - 0.038 14.3 0.2 0.054 13.8 0.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1053) DFF-C PF09033.5 KEG08726.1 - 0.085 12.6 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain SPC22 PF04573.7 KEG08727.1 - 3.7e-17 62.1 0.0 4.4e-17 61.8 0.0 1.3 1 1 0 1 1 1 1 Signal peptidase subunit Cytochrom_B562 PF07361.6 KEG08728.1 - 0.046 14.1 5.9 0.24 11.8 0.2 4.1 4 0 0 4 4 4 0 Cytochrome b562 DUF1043 PF06295.7 KEG08728.1 - 1.7 8.2 10.0 4.8 6.8 0.0 4.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1043) IFP_35_N PF07334.8 KEG08728.1 - 4.1 7.4 8.8 4 7.4 0.1 3.7 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF3972 PF13118.1 KEG08728.1 - 6.8 6.7 11.0 4 7.5 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3972) Na_Ca_ex PF01699.19 KEG08730.1 - 0.056 13.0 0.5 0.056 13.0 0.4 1.6 2 0 0 2 2 2 0 Sodium/calcium exchanger protein FlxA PF14282.1 KEG08731.1 - 0.0087 15.9 7.1 0.0097 15.8 4.9 1.2 1 0 0 1 1 1 1 FlxA-like protein DUF2336 PF10098.4 KEG08731.1 - 0.012 14.9 4.4 0.014 14.6 3.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2336) STAT_bind PF02864.10 KEG08731.1 - 0.12 11.9 0.4 0.11 12.0 0.3 1.1 1 0 0 1 1 1 0 STAT protein, DNA binding domain FERM_M PF00373.13 KEG08731.1 - 0.28 11.3 2.5 0.44 10.7 1.7 1.3 1 0 0 1 1 1 0 FERM central domain DUF2361 PF10153.4 KEG08731.1 - 0.77 9.9 8.9 0.4 10.8 5.1 1.4 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2361) Mto2_bdg PF12808.2 KEG08731.1 - 0.79 9.8 5.0 10 6.2 0.3 2.4 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region GNT-I PF03071.10 KEG08731.1 - 1.4 7.3 5.1 1.5 7.2 3.5 1.0 1 0 0 1 1 1 0 GNT-I family Ion_trans_2 PF07885.11 KEG08732.1 - 4.3e-11 42.3 6.2 4.3e-11 42.3 4.3 1.8 2 0 0 2 2 2 1 Ion channel Coatomer_b_Cpla PF14806.1 KEG08732.1 - 0.15 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform Fumarate_red_C PF02300.12 KEG08732.1 - 1.4 8.8 4.3 0.73 9.7 0.7 2.1 2 0 0 2 2 2 0 Fumarate reductase subunit C Ion_trans_2 PF07885.11 KEG08733.1 - 7e-12 44.9 6.4 2.1e-11 43.3 4.4 1.9 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.26 KEG08733.1 - 0.0045 16.2 1.0 0.0045 16.2 0.7 2.4 3 0 0 3 3 3 1 Ion transport protein Trigger_C PF05698.9 KEG08733.1 - 0.014 15.2 0.1 0.024 14.4 0.1 1.3 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus Lig_chan PF00060.21 KEG08733.1 - 0.073 12.7 1.2 0.18 11.4 0.8 1.7 1 0 0 1 1 1 0 Ligand-gated ion channel DUF2884 PF11101.3 KEG08734.1 - 0.088 12.1 2.3 0.15 11.3 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) SpecificRecomb PF10136.4 KEG08734.1 - 0.17 9.8 0.8 0.27 9.2 0.6 1.2 1 0 0 1 1 1 0 Site-specific recombinase Tetraspannin PF00335.15 KEG08735.1 - 2.7e-13 49.7 3.6 4.1e-13 49.1 2.5 1.3 1 1 0 1 1 1 1 Tetraspanin family Myc_target_1 PF15179.1 KEG08735.1 - 0.1 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Myc target protein 1 SKG6 PF08693.5 KEG08735.1 - 0.22 10.8 0.1 0.22 10.8 0.1 2.4 4 0 0 4 4 4 0 Transmembrane alpha-helix domain UCH PF00443.24 KEG08737.1 - 3.2e-47 160.8 0.0 5.6e-47 160.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEG08737.1 - 4.1e-20 72.4 0.0 1.9e-19 70.2 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-RanBP PF00641.13 KEG08737.1 - 0.0012 17.9 1.0 0.0012 17.9 0.7 2.9 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others ERM PF00769.14 KEG08737.1 - 0.016 14.7 2.0 0.031 13.8 1.4 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family ubiquitin PF00240.18 KEG08737.1 - 0.21 11.0 0.0 13 5.2 0.0 3.2 3 0 0 3 3 3 0 Ubiquitin family Transaldolase PF00923.14 KEG08739.1 - 4.2e-19 68.7 0.0 4.7e-19 68.6 0.0 1.0 1 0 0 1 1 1 1 Transaldolase Sec63 PF02889.11 KEG08741.1 - 1.5e-155 517.1 0.1 1.8e-88 296.7 0.1 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 KEG08741.1 - 2.2e-54 183.4 0.0 6e-29 100.6 0.2 2.8 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 KEG08741.1 - 9.3e-23 81.0 0.0 1.3e-14 54.4 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KEG08741.1 - 2.2e-18 65.8 0.0 1.7e-08 34.2 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain SNF2_N PF00176.18 KEG08741.1 - 1.8e-09 36.8 0.1 3.9e-06 25.8 0.1 2.5 2 0 0 2 2 2 2 SNF2 family N-terminal domain AAA_19 PF13245.1 KEG08741.1 - 2.5e-07 30.3 0.0 0.012 15.3 0.0 3.0 2 0 0 2 2 2 2 Part of AAA domain AAA_22 PF13401.1 KEG08741.1 - 2.7e-07 30.7 0.0 0.002 18.2 0.0 3.6 2 1 0 2 2 2 2 AAA domain AAA_10 PF12846.2 KEG08741.1 - 7.9e-05 22.2 2.2 0.68 9.3 0.0 4.6 4 1 0 5 5 5 1 AAA-like domain T2SE PF00437.15 KEG08741.1 - 9.9e-05 21.3 0.0 0.064 12.1 0.0 2.9 3 0 0 3 3 3 2 Type II/IV secretion system protein PhoH PF02562.11 KEG08741.1 - 0.00078 18.7 0.0 1.2 8.2 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein DUF2075 PF09848.4 KEG08741.1 - 0.0033 16.4 0.0 0.012 14.6 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 KEG08741.1 - 0.022 14.9 2.2 1.1 9.4 0.1 4.0 3 2 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.16 KEG08741.1 - 0.051 12.8 0.9 0.56 9.4 0.0 2.6 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain His_Phos_1 PF00300.17 KEG08742.1 - 0.0048 16.9 0.0 0.028 14.5 0.0 2.1 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Peptidase_M8 PF01457.11 KEG08744.1 - 2.3e-32 112.0 0.2 2.7e-32 111.8 0.1 1.0 1 0 0 1 1 1 1 Leishmanolysin RHSP PF07999.6 KEG08745.1 - 4.1e-26 91.5 0.0 5e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 Retrotransposon hot spot protein SSrecog PF03531.9 KEG08747.1 - 0.063 12.6 0.0 0.084 12.1 0.0 1.1 1 0 0 1 1 1 0 Structure-specific recognition protein (SSRP1) PLDc_2 PF13091.1 KEG08748.1 - 1.2e-07 31.5 0.0 0.00092 18.9 0.0 3.0 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KEG08748.1 - 0.17 11.7 3.0 0.21 11.4 0.1 2.6 3 0 0 3 3 3 0 Phospholipase D Active site motif PTPA PF03095.10 KEG08749.1 - 4.4e-102 341.3 0.0 5e-102 341.0 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Myosin_TH1 PF06017.8 KEG08750.1 - 0.05 12.9 0.0 0.076 12.3 0.0 1.2 1 0 0 1 1 1 0 Myosin tail TMEM171 PF15471.1 KEG08750.1 - 3 6.5 16.2 0.063 12.0 1.2 2.4 2 1 0 2 2 2 0 Transmembrane protein family 171 Cas_APE2256 PF09651.5 KEG08754.1 - 1.3 8.7 5.3 44 3.7 0.1 3.2 1 1 2 3 3 3 0 CRISPR-associated protein (Cas_APE2256) Peptidase_M15_2 PF05951.8 KEG08754.1 - 1.3 8.4 3.8 21 4.5 0.1 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF882) DUF2881 PF11087.3 KEG08754.1 - 2.7 7.5 23.6 1.6 8.2 0.3 4.7 4 1 1 5 5 5 0 Protein of unknown function (DUF2881) Galactosyl_T PF01762.16 KEG08755.1 - 1.9e-07 30.9 0.4 0.0071 15.9 0.1 3.0 3 1 0 3 3 3 2 Galactosyltransferase BUD22 PF09073.5 KEG08757.1 - 1.5 7.7 12.5 0.15 11.1 4.1 2.2 2 0 0 2 2 2 0 BUD22 DUF4351 PF14261.1 KEG08758.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) NDK PF00334.14 KEG08759.1 - 1.2e-54 183.7 0.0 1.4e-54 183.5 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase MCM PF00493.18 KEG08760.1 - 6.2e-125 416.3 0.0 8.6e-125 415.9 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KEG08760.1 - 1.9e-14 54.1 0.0 5.3e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.9 KEG08760.1 - 3.9e-07 29.8 0.0 1.2e-06 28.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KEG08760.1 - 3.3e-05 23.1 0.0 0.0012 18.0 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KEG08760.1 - 0.048 13.2 0.0 0.15 11.6 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEG08760.1 - 0.51 10.2 3.9 9.5 6.1 0.0 3.7 2 1 0 2 2 2 0 AAA ATPase domain Pox_F11 PF04943.7 KEG08761.1 - 0.029 13.2 1.7 0.057 12.2 1.2 1.5 1 0 0 1 1 1 0 Poxvirus F11 protein HWE_HK PF07536.9 KEG08761.1 - 0.43 11.0 8.3 1.3 9.5 0.0 4.0 4 0 0 4 4 4 0 HWE histidine kinase Peptidase_S49_N PF08496.5 KEG08761.1 - 5.6 6.7 15.1 0.17 11.6 3.6 2.7 2 1 0 3 3 3 0 Peptidase family S49 N-terminal PSI_PsaF PF02507.10 KEG08762.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III TBCA PF02970.11 KEG08763.1 - 1.5e-24 85.8 4.2 2e-24 85.4 2.9 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor A Muted PF14942.1 KEG08763.1 - 0.064 13.1 4.6 0.079 12.8 3.2 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein IncA PF04156.9 KEG08763.1 - 0.092 12.3 2.6 0.1 12.1 1.8 1.1 1 0 0 1 1 1 0 IncA protein Phosducin PF02114.11 KEG08764.1 - 6.7e-08 31.5 0.2 7.7e-08 31.3 0.1 1.0 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 KEG08764.1 - 1.2e-07 31.3 0.0 1.8e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.1 KEG08764.1 - 0.00085 19.1 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain DIM1 PF02966.11 KEG08764.1 - 0.026 14.0 0.8 0.043 13.3 0.1 1.6 2 0 0 2 2 2 0 Mitosis protein DIM1 KaiB PF07689.7 KEG08764.1 - 0.088 12.2 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 KaiB domain Methyltransf_25 PF13649.1 KEG08764.1 - 0.14 12.5 0.1 0.26 11.6 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain DUF3833 PF12915.2 KEG08765.1 - 0.026 13.7 0.1 0.039 13.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3833) KASH PF10541.4 KEG08765.1 - 0.12 12.2 2.4 0.47 10.3 0.4 2.5 2 0 0 2 2 2 0 Nuclear envelope localisation domain PfkB PF00294.19 KEG08766.1 - 5.5e-41 140.6 0.0 7.4e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Complex1_LYR PF05347.10 KEG08767.1 - 5.8e-11 42.0 0.3 8.1e-11 41.5 0.2 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KEG08767.1 - 4.4e-09 36.4 0.1 6.4e-09 35.8 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like RepC PF06504.6 KEG08767.1 - 0.047 12.6 0.0 0.058 12.3 0.0 1.1 1 0 0 1 1 1 0 Replication protein C (RepC) Herpes_UL14 PF03580.9 KEG08767.1 - 0.068 12.9 0.1 0.12 12.1 0.0 1.4 1 1 0 1 1 1 0 Herpesvirus UL14-like protein DUF3336 PF11815.3 KEG08768.1 - 1.1e-26 93.0 0.2 1.6e-26 92.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KEG08768.1 - 3.6e-12 46.6 0.2 5.7e-12 45.9 0.1 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase Reo_sigmaC PF04582.7 KEG08769.1 - 8.7 5.4 9.3 27 3.8 0.2 3.7 2 1 1 4 4 4 0 Reovirus sigma C capsid protein Mucin PF01456.12 KEG08771.1 - 2 8.1 13.2 0.13 12.0 4.9 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein Mucin PF01456.12 KEG08772.1 - 0.0039 16.9 0.2 0.0055 16.4 0.1 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein Citrate_synt PF00285.16 KEG08774.1 - 0.019 13.7 4.1 0.023 13.4 2.8 1.0 1 0 0 1 1 1 0 Citrate synthase Ribosomal_60s PF00428.14 KEG08774.1 - 0.22 11.9 24.4 0.053 13.9 14.5 1.8 1 1 1 2 2 2 0 60s Acidic ribosomal protein Peripla_BP_6 PF13458.1 KEG08774.1 - 0.27 10.5 6.4 0.35 10.1 4.4 1.1 1 0 0 1 1 1 0 Periplasmic binding protein Asp-B-Hydro_N PF05279.6 KEG08774.1 - 0.79 9.5 5.2 0.87 9.3 3.6 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region RskA PF10099.4 KEG08774.1 - 6.3 6.5 12.9 7.1 6.3 8.6 1.4 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Cir_N PF10197.4 KEG08774.1 - 7.8 6.6 12.3 0.61 10.1 2.9 2.5 1 1 1 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR NARP1 PF12569.3 KEG08775.1 - 0.00092 18.0 4.2 0.0011 17.8 2.9 1.2 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 IncA PF04156.9 KEG08775.1 - 0.0019 17.8 1.1 0.0022 17.6 0.8 1.2 1 0 0 1 1 1 1 IncA protein BRO1 PF03097.13 KEG08775.1 - 0.0059 15.3 2.8 0.0076 15.0 1.9 1.3 1 0 0 1 1 1 1 BRO1-like domain DegS PF05384.6 KEG08775.1 - 0.0069 15.6 1.9 0.015 14.5 1.3 1.6 1 0 0 1 1 1 1 Sensor protein DegS Macoilin PF09726.4 KEG08775.1 - 0.029 12.6 4.9 0.038 12.2 3.4 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF2797 PF10977.3 KEG08775.1 - 0.034 13.7 2.0 0.044 13.4 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) Thioredoxin_4 PF13462.1 KEG08775.1 - 0.035 14.1 4.8 0.057 13.4 3.3 1.4 1 0 0 1 1 1 0 Thioredoxin ISG65-75 PF11727.3 KEG08775.1 - 0.037 13.0 8.5 0.048 12.7 5.9 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF3450 PF11932.3 KEG08775.1 - 0.05 12.8 6.2 0.073 12.3 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) RNA_pol_Rpb1_5 PF04998.12 KEG08775.1 - 0.12 11.5 0.8 0.14 11.3 0.6 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DUF4446 PF14584.1 KEG08775.1 - 0.13 12.0 1.8 1.2 8.9 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) GAS PF13851.1 KEG08775.1 - 0.15 11.2 8.4 0.45 9.6 5.2 1.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding FadA PF09403.5 KEG08775.1 - 0.2 11.6 8.3 0.33 10.9 5.8 1.4 1 0 0 1 1 1 0 Adhesion protein FadA DUF948 PF06103.6 KEG08775.1 - 0.33 10.8 3.5 0.53 10.1 1.5 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Borrelia_P83 PF05262.6 KEG08775.1 - 0.39 8.9 7.8 0.44 8.7 5.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Cluap1 PF10234.4 KEG08775.1 - 0.42 9.7 6.8 0.26 10.4 3.4 1.5 2 0 0 2 2 2 0 Clusterin-associated protein-1 Syntaxin PF00804.20 KEG08775.1 - 1.3 9.2 7.6 0.12 12.4 0.8 2.1 2 1 1 3 3 2 0 Syntaxin DUF2203 PF09969.4 KEG08775.1 - 1.6 8.9 4.4 3.1 8.0 3.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Mucin PF01456.12 KEG08776.1 - 5.6 6.7 12.7 0.1 12.3 2.9 2.3 2 2 0 2 2 2 0 Mucin-like glycoprotein Hamartin PF04388.7 KEG08777.1 - 3 6.4 11.5 1.2 7.7 6.4 1.3 1 1 0 1 1 1 0 Hamartin protein AIP3 PF03915.8 KEG08778.1 - 0.094 11.6 1.1 0.11 11.4 0.7 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 DUF2613 PF11021.3 KEG08779.1 - 0.11 12.2 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) Ribosomal_L22 PF00237.14 KEG08780.1 - 1e-20 73.6 0.0 1.1e-20 73.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Copper-bind PF00127.15 KEG08780.1 - 0.028 14.6 0.0 0.035 14.3 0.0 1.1 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family WWE PF02825.15 KEG08783.1 - 0.00011 21.5 0.0 0.00022 20.5 0.0 1.5 1 0 0 1 1 1 1 WWE domain DnaJ PF00226.26 KEG08784.1 - 0.0054 16.4 0.1 0.034 13.8 0.0 2.4 2 0 0 2 2 2 1 DnaJ domain Plasmodium_Vir PF05795.6 KEG08784.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein zf-RING_2 PF13639.1 KEG08785.1 - 1.9e-07 30.7 3.8 1.9e-07 30.7 2.6 3.7 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 KEG08785.1 - 0.00023 21.1 3.4 0.00023 21.1 2.4 4.7 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEG08785.1 - 0.00038 20.0 0.5 0.00038 20.0 0.4 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF3592 PF12158.3 KEG08786.1 - 0.00013 21.8 0.2 0.00018 21.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3592) Enkurin PF13864.1 KEG08787.1 - 4.2e-22 78.1 1.3 6.9e-22 77.5 0.9 1.3 1 0 0 1 1 1 1 Calmodulin-binding DUF3552 PF12072.3 KEG08787.1 - 0.31 10.2 3.5 0.75 8.9 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) R_equi_Vir PF05526.6 KEG08789.1 - 2 7.9 4.2 23 4.5 0.7 2.3 2 0 0 2 2 2 0 Rhodococcus equi virulence-associated protein RPA_C PF08784.6 KEG08791.1 - 3.9e-19 68.9 0.9 1.5e-18 67.0 0.0 2.0 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 KEG08791.1 - 8.6e-07 28.7 0.0 1.6e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain GntR PF00392.16 KEG08791.1 - 0.0045 16.4 0.0 0.013 14.9 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_IclR PF09339.5 KEG08791.1 - 0.006 16.1 0.1 0.01 15.4 0.1 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain PaaX PF07848.7 KEG08791.1 - 0.037 14.0 0.0 0.08 12.9 0.0 1.5 1 0 0 1 1 1 0 PaaX-like protein Peptidase_C39 PF03412.10 KEG08791.1 - 0.068 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase C39 family DUF3606 PF12244.3 KEG08791.1 - 0.074 12.6 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) E1-E2_ATPase PF00122.15 KEG08792.1 - 2.5e-64 216.4 3.6 2.5e-64 216.4 2.5 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KEG08792.1 - 1.9e-43 148.1 6.2 1.9e-43 148.1 4.3 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KEG08792.1 - 4.6e-31 108.8 0.0 1.9e-30 106.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KEG08792.1 - 2.8e-20 71.5 1.3 4.8e-20 70.7 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KEG08792.1 - 1.6e-18 66.4 0.1 4.1e-18 65.1 0.1 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KEG08792.1 - 3.8e-16 59.8 0.0 1e-15 58.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KEG08792.1 - 1.7e-08 34.3 0.7 2.7e-06 27.1 0.5 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KEG08792.1 - 0.0076 16.4 0.0 0.018 15.2 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Ribosomal_L21p PF00829.16 KEG08792.1 - 0.2 11.7 1.5 0.46 10.6 1.0 1.6 1 0 0 1 1 1 0 Ribosomal prokaryotic L21 protein Ribosomal_L9_N PF01281.14 KEG08793.1 - 0.00013 21.0 0.0 0.00029 19.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain ABC1 PF03109.11 KEG08794.1 - 3.8e-30 104.3 0.0 9.6e-30 103.0 0.0 1.7 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 KEG08794.1 - 8.4e-06 25.6 0.4 1.6e-05 24.8 0.3 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KEG08794.1 - 0.049 12.7 0.1 0.35 9.9 0.0 2.2 3 0 0 3 3 3 0 Ecdysteroid kinase Pkinase PF00069.20 KEG08794.1 - 0.097 11.8 0.0 0.43 9.6 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain HTH_23 PF13384.1 KEG08794.1 - 0.097 12.3 0.1 0.79 9.4 0.1 2.4 2 0 0 2 2 2 0 Homeodomain-like domain HTH_28 PF13518.1 KEG08794.1 - 0.12 12.4 0.0 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain ThiF PF00899.16 KEG08795.1 - 7.8e-32 109.9 0.1 1.6e-31 108.9 0.0 1.5 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 KEG08795.1 - 1.2e-24 85.6 0.3 2.5e-24 84.6 0.2 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KEG08795.1 - 2.6e-15 55.5 0.7 4.7e-15 54.6 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 KEG08795.1 - 3.9e-15 55.6 0.0 7.7e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.1 KEG08795.1 - 0.00097 19.3 0.2 0.0063 16.7 0.0 2.4 3 0 0 3 3 3 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 KEG08795.1 - 0.0056 16.7 0.1 0.016 15.2 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KEG08795.1 - 0.076 13.4 0.3 0.27 11.6 0.2 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DnaJ PF00226.26 KEG08796.1 - 2.8e-28 97.4 1.8 5.3e-28 96.5 1.3 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KEG08796.1 - 4.9e-23 80.8 1.7 2.6e-18 65.6 0.0 3.7 4 0 0 4 4 4 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KEG08796.1 - 2.5e-14 53.0 13.9 5.4e-14 51.9 9.6 1.6 1 0 0 1 1 1 1 DnaJ central domain DUF2614 PF11023.3 KEG08796.1 - 0.1 12.3 0.8 0.19 11.5 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2614) HypA PF01155.14 KEG08796.1 - 0.61 9.7 8.7 22 4.7 6.2 2.6 2 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family 4HBT PF03061.17 KEG08797.1 - 1.7e-06 28.0 0.0 2.8e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Ovate PF04844.8 KEG08797.1 - 0.051 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Transcriptional repressor, ovate 4HBT PF03061.17 KEG08798.1 - 4.7e-06 26.6 0.0 1.3e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 Thioesterase superfamily Hid1 PF12722.2 KEG08799.1 - 1.3 6.5 2.6 1.7 6.2 1.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RAB3GAP2_N PF14655.1 KEG08799.1 - 4.8 6.0 5.9 0.76 8.7 1.2 1.6 1 1 1 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PAT1 PF09770.4 KEG08799.1 - 6.2 4.9 22.1 9 4.3 15.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GAGA_bind PF06217.7 KEG08799.1 - 9.1 6.1 9.0 15 5.4 6.2 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family PQQ_3 PF13570.1 KEG08800.1 - 0.0013 18.9 3.4 0.013 15.7 0.2 3.2 2 1 0 2 2 2 1 PQQ-like domain WD40 PF00400.27 KEG08800.1 - 0.11 12.4 1.0 2.6 8.0 0.1 2.9 2 0 0 2 2 2 0 WD domain, G-beta repeat RCR PF12273.3 KEG08801.1 - 0.48 10.9 5.0 0.73 10.4 3.5 1.3 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red SNARE PF05739.14 KEG08803.1 - 0.00025 20.6 3.1 0.0014 18.2 1.9 2.0 1 1 0 1 1 1 1 SNARE domain IncA PF04156.9 KEG08805.1 - 0.16 11.5 0.1 0.16 11.5 0.0 1.9 3 0 0 3 3 3 0 IncA protein Abhydrolase_3 PF07859.8 KEG08806.1 - 9.2e-14 51.5 0.0 1.7e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KEG08806.1 - 3.6e-10 39.1 0.1 6.8e-10 38.2 0.0 1.4 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KEG08806.1 - 1.2e-09 38.0 0.0 6.1e-09 35.7 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEG08806.1 - 4.7e-09 36.4 0.3 1e-08 35.3 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEG08806.1 - 1.4e-06 27.6 0.0 0.13 11.4 0.0 3.6 2 2 1 3 3 3 2 Prolyl oligopeptidase family PPI_Ypi1 PF07491.6 KEG08808.1 - 8.8e-18 63.6 4.8 1.6e-17 62.8 3.4 1.5 1 0 0 1 1 1 1 Protein phosphatase inhibitor DUF755 PF05501.6 KEG08808.1 - 0.0069 16.4 7.9 0.0069 16.4 5.5 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF755) TFIIF_alpha PF05793.7 KEG08808.1 - 0.04 12.2 0.4 0.048 12.0 0.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF1117 PF06547.7 KEG08808.1 - 0.044 13.8 0.1 0.061 13.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) TGF_beta PF00019.15 KEG08808.1 - 0.096 12.9 0.5 0.096 12.9 0.3 1.7 2 0 0 2 2 2 0 Transforming growth factor beta like domain Vasculin PF15337.1 KEG08808.1 - 0.29 11.6 3.4 0.42 11.1 2.3 1.3 1 0 0 1 1 1 0 Vascular protein family Vasculin-like 1 FDF PF09532.5 KEG08808.1 - 0.72 10.4 3.8 1.1 9.7 2.7 1.4 1 1 0 1 1 1 0 FDF domain SR-25 PF10500.4 KEG08808.1 - 1.5 8.1 9.8 2.1 7.7 6.7 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein TSC22 PF01166.13 KEG08809.1 - 0.0059 16.5 4.5 0.042 13.8 0.3 2.6 2 0 0 2 2 2 1 TSC-22/dip/bun family DUF2880 PF11082.3 KEG08809.1 - 0.026 14.4 1.0 6.9 6.6 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2880) DUF2450 PF10475.4 KEG08809.1 - 0.14 11.0 0.7 0.33 9.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) Pkinase PF00069.20 KEG08810.1 - 2.6e-49 167.7 0.0 9.1e-25 87.2 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 KEG08810.1 - 1.2e-20 73.7 0.0 3.4e-16 59.1 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.1 KEG08810.1 - 0.0021 17.0 0.0 0.82 8.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 KEG08810.1 - 0.038 13.0 0.0 0.07 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEG08810.1 - 0.061 13.0 0.1 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family DZR PF12773.2 KEG08810.1 - 0.094 12.5 2.7 0.91 9.3 2.0 2.2 1 1 0 1 1 1 0 Double zinc ribbon UPF0547 PF10571.4 KEG08810.1 - 0.25 11.0 3.7 8.6 6.1 0.4 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zinc_ribbon_2 PF13240.1 KEG08810.1 - 0.58 9.7 8.4 4.1 7.0 0.3 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 KEG08810.1 - 0.64 9.2 7.9 1.1 8.5 0.2 3.0 3 0 0 3 3 3 0 zinc-ribbon domain zf-Mss51 PF13824.1 KEG08810.1 - 8 6.4 5.9 6.2 6.7 0.4 2.8 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Spc7 PF08317.6 KEG08812.1 - 0.0039 15.9 1.0 0.006 15.2 0.7 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein DGF-1_C PF11040.3 KEG08812.1 - 0.018 14.9 1.4 0.034 14.0 0.6 1.7 1 1 1 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DUF2913 PF11140.3 KEG08812.1 - 0.026 13.8 0.7 0.039 13.2 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2913) Atg14 PF10186.4 KEG08812.1 - 0.052 12.4 3.6 0.066 12.1 2.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 LMBR1 PF04791.11 KEG08812.1 - 0.077 11.5 0.4 0.084 11.4 0.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Bacillus_HBL PF05791.6 KEG08812.1 - 0.088 12.1 0.6 0.15 11.4 0.4 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) CENP-Q PF13094.1 KEG08812.1 - 0.6 10.1 7.0 0.053 13.5 1.8 1.5 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Fib_alpha PF08702.5 KEG08812.1 - 2.1 8.4 5.6 0.36 10.9 1.5 1.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family IncA PF04156.9 KEG08812.1 - 7.8 6.0 11.5 0.23 11.0 3.5 1.7 2 0 0 2 2 2 0 IncA protein Peptidase_M28 PF04389.12 KEG08813.1 - 6.3e-24 84.6 0.2 3e-14 53.1 0.1 3.2 2 1 0 2 2 2 2 Peptidase family M28 AFG1_ATPase PF03969.11 KEG08814.1 - 1.4e-81 274.1 1.3 4.2e-76 256.1 0.0 2.9 1 1 2 3 3 3 2 AFG1-like ATPase Bac_DnaA PF00308.13 KEG08814.1 - 0.00062 19.4 0.2 0.014 15.0 0.2 2.2 1 1 0 1 1 1 1 Bacterial dnaA protein AAA_22 PF13401.1 KEG08814.1 - 0.0011 19.0 0.0 0.0024 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEG08814.1 - 0.0073 16.3 0.0 0.017 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 KEG08814.1 - 0.0083 16.3 0.0 0.018 15.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KEG08814.1 - 0.073 12.7 0.0 0.29 10.7 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 KEG08814.1 - 0.075 12.7 0.0 0.18 11.4 0.0 1.7 2 0 0 2 2 2 0 Archaeal ATPase ABC_tran PF00005.22 KEG08814.1 - 0.16 12.2 0.0 0.54 10.5 0.0 1.9 2 1 0 2 2 2 0 ABC transporter Lectin_leg-like PF03388.8 KEG08815.1 - 1.5e-12 47.1 0.0 3.9e-05 22.8 0.0 3.3 4 0 0 4 4 4 2 Legume-like lectin family Cortex-I_coil PF09304.5 KEG08816.1 - 0.01 15.8 6.7 0.01 15.8 4.7 3.3 2 1 1 3 3 3 0 Cortexillin I, coiled coil ERM PF00769.14 KEG08816.1 - 0.038 13.5 25.3 0.066 12.7 9.5 2.3 2 0 0 2 2 2 0 Ezrin/radixin/moesin family RabGAP-TBC PF00566.13 KEG08817.1 - 5.7e-33 114.2 0.0 7.6e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pex24p PF06398.6 KEG08817.1 - 2.3e-10 39.8 3.8 2.3e-10 39.8 2.6 1.6 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin PIF1 PF05970.9 KEG08818.1 - 5.2e-46 157.2 0.1 1.2e-38 133.0 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 KEG08818.1 - 3.5e-15 56.0 0.0 8.5e-15 54.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.9 KEG08818.1 - 3.2e-11 41.7 0.5 1.9e-07 29.2 0.0 2.3 2 0 0 2 2 2 2 Helicase AAA_22 PF13401.1 KEG08818.1 - 1.4e-06 28.4 0.0 3.4e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEG08818.1 - 3.1e-06 26.8 1.1 1.4e-05 24.7 0.8 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KEG08818.1 - 1.1e-05 25.4 0.2 2.8e-05 24.1 0.2 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 KEG08818.1 - 0.00011 21.9 0.1 0.00047 19.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) UvrD_C_2 PF13538.1 KEG08818.1 - 0.00011 22.2 0.0 0.00043 20.3 0.0 2.0 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain T2SE PF00437.15 KEG08818.1 - 0.0049 15.8 0.0 0.018 13.9 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein AFG1_ATPase PF03969.11 KEG08818.1 - 0.0059 15.4 0.0 0.011 14.5 0.0 1.4 1 0 0 1 1 1 1 AFG1-like ATPase Viral_helicase1 PF01443.13 KEG08818.1 - 0.0072 15.8 0.1 0.092 12.2 0.1 2.6 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.1 KEG08818.1 - 0.013 14.9 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KEG08818.1 - 0.02 15.1 0.0 0.046 14.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.7 KEG08818.1 - 0.032 13.8 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.10 KEG08818.1 - 0.036 13.7 0.1 0.52 10.0 0.1 2.3 2 0 0 2 2 2 0 NTPase IstB_IS21 PF01695.12 KEG08818.1 - 0.038 13.3 0.0 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein Helicase_RecD PF05127.9 KEG08818.1 - 0.043 13.4 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 Helicase AAA_7 PF12775.2 KEG08818.1 - 0.056 12.5 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region D3 AAA PF00004.24 KEG08818.1 - 0.1 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 KEG08818.1 - 0.11 11.4 0.0 0.23 10.4 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) TIP49 PF06068.8 KEG08818.1 - 0.13 10.9 0.0 1.1 7.9 0.0 2.2 2 0 0 2 2 2 0 TIP49 C-terminus AAA_14 PF13173.1 KEG08818.1 - 0.13 12.1 0.0 0.34 10.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.1 KEG08818.1 - 0.14 11.7 0.0 11 5.5 0.0 2.4 1 1 1 2 2 2 0 AAA domain Rotamase PF00639.16 KEG08819.1 - 3.1e-23 82.2 0.0 3.6e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 KEG08819.1 - 2.4e-16 60.0 0.0 2.7e-16 59.8 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 KEG08819.1 - 1.9e-05 25.2 0.0 2.4e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Exonuc_VII_S PF02609.11 KEG08819.1 - 0.00063 19.4 0.1 0.0059 16.3 0.0 2.1 2 0 0 2 2 2 1 Exonuclease VII small subunit UPF0150 PF03681.10 KEG08819.1 - 0.038 13.6 0.1 0.078 12.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0150) FUSC PF04632.7 KEG08820.1 - 5e-05 21.9 12.0 5e-05 21.9 8.3 2.9 2 1 1 3 3 3 1 Fusaric acid resistance protein family DUF971 PF06155.7 KEG08820.1 - 0.64 10.4 8.0 6.8 7.1 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF971) Reo_sigmaC PF04582.7 KEG08820.1 - 6.7 5.7 18.9 5.7 6.0 0.9 3.6 1 1 1 3 3 3 0 Reovirus sigma C capsid protein Methyltransf_31 PF13847.1 KEG08822.1 - 7e-06 25.6 0.0 9.5e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEG08822.1 - 2.1e-05 24.5 0.2 3.2e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEG08822.1 - 0.00079 19.8 0.0 0.0011 19.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEG08822.1 - 0.0008 19.9 0.1 0.0021 18.6 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEG08822.1 - 0.0012 19.1 0.0 0.0017 18.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEG08822.1 - 0.018 15.4 1.1 0.085 13.3 0.1 2.3 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.1 KEG08822.1 - 0.028 14.1 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PTPlike_phytase PF14566.1 KEG08823.1 - 1.7e-107 355.9 2.8 4.8e-42 143.5 0.0 3.8 3 0 0 3 3 3 3 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 KEG08823.1 - 0.046 13.9 1.9 5.1 7.3 0.0 3.7 5 0 0 5 5 5 0 Tyrosine phosphatase family zf-DHHC PF01529.15 KEG08824.1 - 3.8e-34 117.5 0.7 6.2e-34 116.8 0.5 1.3 1 1 0 1 1 1 1 DHHC palmitoyltransferase Fer4_8 PF13183.1 KEG08824.1 - 0.0039 17.1 0.3 0.0091 16.0 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S dicluster domain zf-ribbon_3 PF13248.1 KEG08824.1 - 0.024 13.8 1.3 0.047 12.9 0.9 1.5 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.2 KEG08824.1 - 0.062 13.1 9.3 0.094 12.5 6.5 1.2 1 0 0 1 1 1 0 Double zinc ribbon NfeD PF01957.13 KEG08824.1 - 0.3 11.2 3.5 0.5 10.4 2.4 1.3 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding zinc_ribbon_2 PF13240.1 KEG08824.1 - 1.7 8.2 7.7 3.5 7.2 5.3 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zf-DHHC PF01529.15 KEG08825.1 - 2.5e-36 124.6 8.8 2.5e-36 124.6 6.1 1.5 1 1 0 1 1 1 1 DHHC palmitoyltransferase Transglut_core3 PF13471.1 KEG08825.1 - 0.017 14.9 0.1 0.041 13.6 0.1 1.6 1 0 0 1 1 1 0 Transglutaminase-like superfamily PSI PF01437.20 KEG08825.1 - 0.029 14.5 7.8 0.69 10.1 2.1 2.6 2 0 0 2 2 2 0 Plexin repeat Carla_C4 PF01623.12 KEG08826.1 - 0.079 12.7 0.1 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Carlavirus putative nucleic acid binding protein DUF914 PF06027.7 KEG08828.1 - 1.4e-50 172.0 9.8 1.6e-45 155.3 1.3 2.0 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF914) TPT PF03151.11 KEG08828.1 - 2.1e-05 24.2 10.9 0.028 14.0 4.5 2.8 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 KEG08828.1 - 0.0011 19.0 5.4 0.0011 19.0 3.7 2.6 2 1 0 2 2 2 1 EamA-like transporter family UPF0139 PF03669.8 KEG08828.1 - 0.043 13.3 0.2 2.1 7.8 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) NfeD PF01957.13 KEG08828.1 - 0.47 10.5 0.0 0.47 10.5 0.0 2.4 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding RAMP PF04901.8 KEG08830.1 - 0.001 18.8 0.3 0.0037 17.0 0.2 2.0 1 1 0 1 1 1 1 Receptor activity modifying family RDD PF06271.7 KEG08830.1 - 0.0031 17.4 1.4 0.0044 16.9 1.0 1.2 1 0 0 1 1 1 1 RDD family DUF2705 PF10920.3 KEG08830.1 - 0.034 13.3 0.7 0.063 12.4 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2705) Tad PF13400.1 KEG08830.1 - 3.4 7.7 7.2 9.8 6.3 0.4 2.3 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like RNA_pol_Rpb1_5 PF04998.12 KEG08833.1 - 6.6e-07 28.8 0.0 8.1e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 Peptidase_M8 PF01457.11 KEG08835.1 - 6.4e-139 463.6 1.0 7.3e-139 463.4 0.7 1.0 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M10 PF00413.19 KEG08835.1 - 0.068 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Matrixin DUF2262 PF10020.4 KEG08836.1 - 0.15 12.2 0.2 0.34 11.1 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2262) DUF423 PF04241.10 KEG08837.1 - 5.6e-18 64.6 3.2 7.6e-18 64.2 2.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF423) DUF3488 PF11992.3 KEG08837.1 - 0.05 12.2 1.4 0.061 11.9 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) DUF805 PF05656.9 KEG08837.1 - 0.22 11.3 2.1 0.37 10.6 1.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF805) IncA PF04156.9 KEG08837.1 - 3.9 7.0 11.4 6 6.4 2.3 2.1 2 0 0 2 2 2 0 IncA protein HBS1_N PF08938.5 KEG08838.1 - 0.034 14.2 1.0 1.3 9.1 0.0 2.4 2 1 0 2 2 2 0 HBS1 N-terminus zf-HC2 PF13490.1 KEG08838.1 - 0.12 12.3 3.2 3.4 7.6 0.7 2.5 2 0 0 2 2 2 0 Putative zinc-finger Sec2p PF06428.6 KEG08840.1 - 0.022 14.5 1.2 0.022 14.5 0.9 4.0 3 1 0 3 3 3 0 GDP/GTP exchange factor Sec2p Herpes_UL87 PF03043.9 KEG08840.1 - 1.4 7.2 6.2 2.1 6.6 4.3 1.3 1 0 0 1 1 1 0 Herpesvirus UL87 family Kinesin PF00225.18 KEG08841.1 - 4.1e-96 321.6 0.1 9.9e-95 317.0 0.0 2.9 2 1 0 2 2 2 1 Kinesin motor domain PEGA PF08308.6 KEG08841.1 - 0.03 14.1 0.7 0.23 11.2 0.1 2.6 2 0 0 2 2 2 0 PEGA domain SUN PF03856.8 KEG08841.1 - 0.21 10.8 0.1 9.3 5.4 0.0 2.3 2 0 0 2 2 2 0 Beta-glucosidase (SUN family) Ldh_1_N PF00056.18 KEG08842.1 - 1.2e-36 125.5 0.1 2.5e-36 124.5 0.0 1.5 1 1 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KEG08842.1 - 2.4e-31 108.7 0.0 3.3e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Methyltransf_23 PF13489.1 KEG08843.1 - 9.6e-11 41.6 0.0 3.1e-10 40.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEG08843.1 - 7.7e-09 35.9 0.0 1.9e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEG08843.1 - 8.4e-09 35.8 0.0 2e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEG08843.1 - 0.00026 20.6 0.0 0.00046 19.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KEG08843.1 - 0.028 14.0 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_18 PF12847.2 KEG08843.1 - 0.031 14.8 0.0 0.065 13.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ank_2 PF12796.2 KEG08844.1 - 2.5e-19 69.4 6.2 4.6e-09 36.5 0.1 5.4 2 2 4 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 KEG08844.1 - 5.6e-14 51.1 9.1 0.014 15.1 0.0 8.5 8 1 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.1 KEG08844.1 - 1.6e-13 50.3 4.5 0.0014 18.8 0.1 7.5 7 1 1 8 8 8 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEG08844.1 - 1.9e-12 47.3 1.0 0.011 16.2 0.0 6.9 4 2 4 8 8 8 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEG08844.1 - 2.3e-09 36.5 4.9 0.061 13.5 0.0 7.5 8 0 0 8 8 8 2 Ankyrin repeat Sel1 PF08238.7 KEG08845.1 - 4.2e-22 78.0 31.8 7.2e-06 26.4 0.1 8.3 8 0 0 8 8 8 7 Sel1 repeat TPR_7 PF13176.1 KEG08845.1 - 0.019 14.7 5.1 1.2 9.1 0.0 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat ETF_QO PF05187.8 KEG08846.1 - 5.3e-39 132.6 0.0 9.3e-39 131.8 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 KEG08846.1 - 5.6e-10 38.6 0.1 8.6e-05 21.5 0.9 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEG08846.1 - 9.6e-07 28.7 0.2 2.7e-06 27.3 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KEG08846.1 - 8.4e-06 24.4 0.3 0.00016 20.3 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 KEG08846.1 - 1.9e-05 24.6 0.0 3.6e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KEG08846.1 - 2.9e-05 23.1 1.2 0.00022 20.2 1.4 1.9 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 KEG08846.1 - 7.8e-05 21.7 0.2 0.00011 21.2 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.2 KEG08846.1 - 0.00011 21.3 0.0 0.00018 20.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEG08846.1 - 0.00032 20.8 0.0 0.00063 19.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEG08846.1 - 0.00097 18.9 0.1 0.0019 18.0 0.1 1.6 1 1 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.12 KEG08846.1 - 0.0017 17.4 0.2 0.003 16.6 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 KEG08846.1 - 0.0047 16.0 0.1 0.023 13.7 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 KEG08846.1 - 0.012 14.5 0.5 0.019 13.8 0.4 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 KEG08846.1 - 0.018 13.7 0.2 0.029 12.9 0.2 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.22 KEG08846.1 - 0.04 14.3 0.1 0.61 10.5 0.2 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.2 KEG08846.1 - 0.08 13.3 1.0 0.21 12.0 0.7 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Nucleoplasmin PF03066.10 KEG08847.1 - 0.015 14.8 2.2 0.02 14.3 1.5 1.5 1 1 0 1 1 1 0 Nucleoplasmin RNA_polI_A34 PF08208.6 KEG08847.1 - 1.9 8.0 11.3 2.6 7.6 7.8 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Gasdermin PF04598.7 KEG08849.1 - 0.00091 18.0 1.6 0.00091 18.0 1.1 2.0 2 0 0 2 2 2 1 Gasdermin family TPD52 PF04201.10 KEG08849.1 - 0.016 14.9 9.4 0.31 10.7 1.1 3.2 2 1 0 2 2 2 0 Tumour protein D52 family UIM PF02809.15 KEG08849.1 - 0.078 12.5 0.4 0.078 12.5 0.3 2.8 2 1 1 3 3 3 0 Ubiquitin interaction motif HXXSHH PF07586.6 KEG08849.1 - 0.61 8.9 6.1 0.048 12.5 0.4 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1552) TMF_DNA_bd PF12329.3 KEG08849.1 - 1.1 9.0 34.4 4.9 7.0 0.1 6.5 5 1 0 6 6 6 0 TATA element modulatory factor 1 DNA binding DUF3037 PF11236.3 KEG08849.1 - 2.3 8.3 7.1 14 5.8 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3037) Flu_NS2 PF00601.14 KEG08849.1 - 2.3 8.4 10.4 6.3 7.0 0.1 3.9 4 0 0 4 4 4 0 Influenza non-structural protein (NS2) Fib_alpha PF08702.5 KEG08849.1 - 2.8 8.0 19.8 0.26 11.4 0.3 3.8 3 1 0 4 4 4 0 Fibrinogen alpha/beta chain family DUF2400 PF09674.5 KEG08849.1 - 5.2 6.6 6.0 0.8 9.3 0.4 2.3 3 1 1 4 4 4 0 Protein of unknown function (DUF2400) Metal_resist PF13801.1 KEG08850.1 - 0.0057 16.6 0.7 0.0084 16.0 0.3 1.5 1 1 0 1 1 1 1 Heavy-metal resistance APG6 PF04111.7 KEG08850.1 - 0.062 12.3 1.1 0.074 12.0 0.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Cep57_CLD_2 PF14197.1 KEG08850.1 - 0.19 11.7 2.6 3.3 7.6 0.9 2.5 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF919 PF06034.6 KEG08850.1 - 0.56 9.8 0.1 0.56 9.8 0.1 2.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF919) DUF4200 PF13863.1 KEG08850.1 - 1.9 8.4 6.3 18 5.3 3.6 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) HMG_box PF00505.14 KEG08851.1 - 0.0048 17.1 1.0 0.0048 17.1 0.7 5.0 5 1 1 6 6 6 1 HMG (high mobility group) box DUF948 PF06103.6 KEG08851.1 - 5.7 6.8 13.0 8.4 6.3 0.7 4.4 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Ribosomal_L1 PF00687.16 KEG08853.1 - 6.6e-12 45.2 0.0 8.8e-06 25.2 0.0 2.4 2 1 1 3 3 3 2 Ribosomal protein L1p/L10e family PIF1 PF05970.9 KEG08854.1 - 2.7e-40 138.4 0.0 2.5e-36 125.4 0.0 2.6 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 KEG08854.1 - 6.6e-13 48.6 0.1 2e-12 47.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KEG08854.1 - 2.2e-09 36.9 5.7 3.4e-09 36.3 2.5 2.4 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 KEG08854.1 - 3e-07 30.2 0.8 0.028 13.9 0.2 3.0 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 KEG08854.1 - 5.9e-06 26.3 0.0 1.5e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_11 PF13086.1 KEG08854.1 - 0.00038 20.1 1.3 0.44 10.0 0.3 2.8 2 1 1 3 3 3 2 AAA domain AAA_22 PF13401.1 KEG08854.1 - 0.0008 19.5 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.16 KEG08854.1 - 0.0014 18.0 0.3 0.0022 17.3 0.2 1.3 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain TrwB_AAD_bind PF10412.4 KEG08854.1 - 0.0022 16.7 0.3 0.0036 15.9 0.2 1.2 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain DUF2075 PF09848.4 KEG08854.1 - 0.0041 16.1 0.1 0.027 13.4 0.2 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 KEG08854.1 - 0.0094 15.9 0.7 0.065 13.2 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.10 KEG08854.1 - 0.019 14.6 0.2 4 7.1 0.1 2.5 1 1 1 2 2 2 0 NTPase PhoH PF02562.11 KEG08854.1 - 0.022 14.0 0.0 0.042 13.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DEAD PF00270.24 KEG08854.1 - 0.023 14.1 0.1 0.11 11.9 0.0 1.9 1 1 0 2 2 2 0 DEAD/DEAH box helicase Herpes_Helicase PF02689.9 KEG08854.1 - 0.045 11.5 1.0 0.92 7.1 0.0 2.1 2 0 0 2 2 2 0 Helicase NACHT PF05729.7 KEG08854.1 - 0.1 12.2 0.1 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 NACHT domain Arch_ATPase PF01637.13 KEG08854.1 - 0.15 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase IMPDH PF00478.20 KEG08857.1 - 8.2e-134 445.9 4.1 9.6e-134 445.7 2.8 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 KEG08857.1 - 5.8e-12 45.1 0.0 6.9e-05 22.5 0.0 2.6 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 KEG08857.1 - 1.4e-09 37.5 4.2 1.1e-05 24.8 0.6 2.6 3 0 0 3 3 3 2 Nitronate monooxygenase FMN_dh PF01070.13 KEG08857.1 - 3.3e-09 36.0 0.7 7e-09 34.9 0.5 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 KEG08857.1 - 0.00077 18.7 0.3 0.05 12.8 0.0 2.3 1 1 1 2 2 2 1 Histidine biosynthesis protein Aldolase PF01081.14 KEG08857.1 - 0.0096 15.1 0.4 0.063 12.4 0.1 2.2 2 0 0 2 2 2 1 KDPG and KHG aldolase Glu_synthase PF01645.12 KEG08857.1 - 0.014 14.2 1.1 0.026 13.4 0.8 1.4 1 0 0 1 1 1 0 Conserved region in glutamate synthase ELMO_CED12 PF04727.8 KEG08858.1 - 1.3e-27 96.4 0.0 1.7e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3092 PF11289.3 KEG08858.1 - 0.095 11.8 0.3 0.13 11.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3092) Peptidase_M41 PF01434.13 KEG08860.1 - 1.1e-41 142.7 0.1 1.6e-41 142.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KEG08860.1 - 3.3e-39 134.0 0.0 8.1e-39 132.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEG08860.1 - 9.9e-06 25.7 0.6 0.0011 19.1 0.1 3.8 3 2 0 3 3 3 1 AAA domain AAA_25 PF13481.1 KEG08860.1 - 0.00028 20.3 1.9 0.003 16.9 0.2 2.5 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 KEG08860.1 - 0.0004 21.1 0.0 0.0014 19.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEG08860.1 - 0.00042 20.0 0.1 0.002 17.8 0.1 2.3 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KEG08860.1 - 0.00072 19.5 4.7 0.0011 18.9 0.1 3.0 3 1 0 3 3 3 1 AAA ATPase domain Zeta_toxin PF06414.7 KEG08860.1 - 0.00093 18.3 0.2 0.038 13.0 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_5 PF07728.9 KEG08860.1 - 0.0014 18.3 0.0 0.0051 16.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KEG08860.1 - 0.0084 15.1 0.0 0.019 14.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 KEG08860.1 - 0.0098 14.6 0.0 0.017 13.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 KEG08860.1 - 0.011 15.1 0.1 0.032 13.6 0.1 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.4 KEG08860.1 - 0.033 13.1 0.0 0.051 12.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.1 KEG08860.1 - 0.033 14.0 0.0 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Peptidase_M50B PF13398.1 KEG08860.1 - 0.045 13.1 0.0 0.088 12.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase M50B-like AAA_3 PF07726.6 KEG08860.1 - 0.056 13.0 0.1 0.77 9.3 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 KEG08860.1 - 0.093 12.6 0.3 0.51 10.2 0.0 2.4 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 KEG08860.1 - 0.097 12.9 0.1 0.18 12.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KEG08860.1 - 0.19 11.4 0.4 0.9 9.2 0.1 2.0 1 1 1 2 2 2 0 NTPase Pkinase PF00069.20 KEG08861.1 - 4.1e-34 117.9 0.0 4.8e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG08861.1 - 4.2e-18 65.3 0.0 5.4e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG08861.1 - 4.6e-10 38.9 0.0 5.9e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KEG08861.1 - 0.00058 19.2 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.6 KEG08861.1 - 0.00083 18.2 0.0 0.0014 17.5 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 KEG08861.1 - 0.0089 15.7 0.5 0.16 11.6 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KEG08861.1 - 0.0099 14.9 0.1 0.02 13.9 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family BTB_2 PF02214.17 KEG08862.1 - 1.7e-11 44.1 0.0 3.3e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KEG08862.1 - 0.0092 15.9 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Nodulin-like PF06813.8 KEG08866.1 - 5.4e-17 61.8 21.5 1.8e-15 56.9 14.9 2.5 1 1 0 1 1 1 1 Nodulin-like Asn_synthase PF00733.16 KEG08867.1 - 5.7e-34 117.7 0.1 5.2e-20 72.0 0.0 2.6 3 0 0 3 3 3 2 Asparagine synthase GATase_7 PF13537.1 KEG08867.1 - 0.01 15.5 0.2 0.12 12.1 0.0 2.8 3 1 0 3 3 3 1 Glutamine amidotransferase domain TRH PF05438.7 KEG08868.1 - 0.035 13.5 0.1 0.045 13.1 0.1 1.2 1 0 0 1 1 1 0 Thyrotropin-releasing hormone (TRH) Ank_4 PF13637.1 KEG08869.1 - 4e-10 39.9 0.0 8.5e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KEG08869.1 - 4.4e-09 36.5 0.1 1.1e-08 35.3 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KEG08869.1 - 2.5e-06 27.1 0.1 0.0061 16.6 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.25 KEG08869.1 - 0.00016 21.3 0.3 0.24 11.2 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 KEG08869.1 - 0.00045 20.3 0.0 0.0015 18.6 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Acetyltransf_1 PF00583.19 KEG08869.1 - 0.00077 19.4 0.0 0.0026 17.7 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEG08869.1 - 0.0079 16.3 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KEG08869.1 - 0.11 12.3 0.1 0.54 10.1 0.0 2.1 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain MFS_1_like PF12832.2 KEG08871.1 - 0.0021 17.7 1.4 0.0022 17.7 0.2 1.7 2 0 0 2 2 2 1 MFS_1 like family Pardaxin PF07425.6 KEG08871.1 - 0.18 11.2 1.1 14 5.1 0.0 2.5 2 0 0 2 2 2 0 Pardaxin Cwf_Cwc_15 PF04889.7 KEG08872.1 - 5.3e-08 32.8 5.1 9.6e-08 32.0 2.1 1.9 1 1 1 2 2 2 1 Cwf15/Cwc15 cell cycle control protein U79_P34 PF03064.11 KEG08872.1 - 0.21 11.1 11.2 0.26 10.7 7.8 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 CDC45 PF02724.9 KEG08872.1 - 0.47 8.4 7.8 0.49 8.3 5.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Med21 PF11221.3 KEG08872.1 - 2.2 8.2 5.5 0.75 9.7 1.4 1.9 2 0 0 2 2 2 0 Subunit 21 of Mediator complex ABC1 PF03109.11 KEG08873.1 - 1.2e-28 99.4 0.0 4.9e-28 97.4 0.0 2.1 2 0 0 2 2 2 1 ABC1 family Pkinase PF00069.20 KEG08873.1 - 0.047 12.8 0.0 0.085 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain WaaY PF06176.6 KEG08873.1 - 0.12 11.6 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.18 KEG08873.1 - 0.24 11.0 7.3 0.43 10.2 0.1 3.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family MFS_1 PF07690.11 KEG08874.1 - 2.2e-19 69.4 44.5 2.7e-12 46.0 13.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.11 KEG08874.1 - 5.5e-11 41.8 20.5 9.5e-11 41.0 14.2 1.3 1 1 0 1 1 1 1 Nucleoside H+ symporter MFS_1_like PF12832.2 KEG08874.1 - 6.7e-07 29.0 1.9 1.5e-06 27.8 0.1 2.5 2 0 0 2 2 2 1 MFS_1 like family DGF-1_5 PF11038.3 KEG08875.1 - 3.1e-117 390.7 10.5 4.3e-117 390.2 7.3 1.2 1 0 0 1 1 1 1 Dispersed gene family protein 1 of Trypanosoma cruzi region 5 DGF-1_4 PF11024.3 KEG08875.1 - 0.0085 16.4 0.5 0.026 14.8 0.3 1.8 1 0 0 1 1 1 1 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 Snf7 PF03357.16 KEG08877.1 - 1.5e-28 99.3 25.8 1.5e-28 99.3 17.9 1.5 2 0 0 2 2 2 1 Snf7 DUF3502 PF12010.3 KEG08877.1 - 7.5e-05 22.7 4.4 0.00018 21.4 3.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3502) MutS_II PF05188.12 KEG08877.1 - 0.1 12.6 2.4 0.14 12.2 0.8 1.8 1 1 1 2 2 2 0 MutS domain II Fes1 PF08609.5 KEG08877.1 - 4.6 7.7 16.9 13 6.3 2.4 3.7 3 1 1 4 4 4 0 Nucleotide exchange factor Fes1 tRNA-synt_2b PF00587.20 KEG08878.1 - 3.1e-55 186.4 0.1 4.7e-55 185.8 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KEG08878.1 - 2.4e-16 59.4 0.1 7e-16 57.9 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain KfrA_N PF11740.3 KEG08880.1 - 0.01 16.2 0.6 0.018 15.5 0.4 1.2 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term DUF3053 PF11254.3 KEG08880.1 - 0.053 12.7 0.3 0.079 12.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) Atg14 PF10186.4 KEG08880.1 - 0.079 11.8 3.9 0.11 11.4 2.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CENP-F_leu_zip PF10473.4 KEG08880.1 - 0.25 11.2 7.7 0.24 11.2 1.3 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-C3HC4_3 PF13920.1 KEG08881.1 - 2.6e-17 62.2 26.8 3.8e-12 45.6 7.9 5.0 4 1 1 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEG08881.1 - 3.2e-06 27.0 27.4 5.3e-06 26.3 6.3 4.8 4 1 1 6 6 6 2 Zinc finger, C3HC4 type (RING finger) DUF1180 PF06679.7 KEG08881.1 - 0.12 12.2 0.9 1.6 8.6 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) VHS PF00790.14 KEG08883.1 - 1.2e-12 47.6 0.0 3e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 VHS domain zf-LYAR PF08790.6 KEG08883.1 - 0.022 14.4 0.0 0.05 13.3 0.0 1.6 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger Zip PF02535.17 KEG08883.1 - 1 8.2 4.0 5.7 5.8 0.1 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter DUF904 PF06005.7 KEG08885.1 - 0.26 11.6 9.6 9.3 6.6 6.6 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Toxin_39 PF15500.1 KEG08885.1 - 3 8.0 7.3 3.6 7.7 1.7 2.6 1 1 2 3 3 3 0 Putative RNase-like toxin Ribosomal_S2 PF00318.15 KEG08886.1 - 4.9e-43 146.8 0.2 4.6e-22 78.2 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 DUF4496 PF14908.1 KEG08887.1 - 1.2e-35 122.4 0.0 1.9e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4496) PUF PF00806.14 KEG08888.1 - 9.3e-11 40.5 0.6 0.0027 17.1 0.0 4.3 4 0 0 4 4 4 2 Pumilio-family RNA binding repeat Zip PF02535.17 KEG08888.1 - 0.92 8.4 20.4 0.66 8.9 0.0 2.4 2 0 0 2 2 2 0 ZIP Zinc transporter Pkinase PF00069.20 KEG08889.1 - 4.2e-57 193.2 0.0 5.2e-57 192.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG08889.1 - 5.7e-26 91.1 0.0 8e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG08889.1 - 2.5e-05 23.4 0.0 4.9e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KEG08889.1 - 4.1e-05 23.4 0.1 0.0014 18.3 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KEG08889.1 - 0.042 12.6 0.0 0.07 11.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 PSP1 PF04468.7 KEG08890.1 - 2e-13 50.1 1.7 2.9e-13 49.6 1.2 1.2 1 0 0 1 1 1 1 PSP1 C-terminal conserved region PAP2_C PF14360.1 KEG08891.1 - 8.6e-19 67.5 10.7 8.6e-19 67.5 7.4 2.3 3 0 0 3 3 3 1 PAP2 superfamily C-terminal Mucin PF01456.12 KEG08892.1 - 8.5e-05 22.3 7.0 0.0001 22.0 4.8 1.1 1 0 0 1 1 1 1 Mucin-like glycoprotein SSP160 PF06933.6 KEG08892.1 - 0.0081 14.1 6.7 0.0076 14.3 4.7 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 DUF1505 PF07403.6 KEG08892.1 - 0.011 15.6 0.8 0.013 15.4 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1505) Bap31 PF05529.7 KEG08892.1 - 0.016 14.7 0.0 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like UPF0239 PF06783.6 KEG08892.1 - 0.065 13.1 0.0 0.085 12.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) Dicty_REP PF05086.7 KEG08892.1 - 0.13 9.9 7.0 0.15 9.8 4.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein ETX_MTX2 PF03318.8 KEG08892.1 - 0.18 11.3 12.3 0.22 11.0 8.5 1.1 1 0 0 1 1 1 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 SoxE PF06525.6 KEG08892.1 - 0.2 10.8 3.8 0.27 10.4 2.7 1.1 1 0 0 1 1 1 0 Sulfocyanin (SoxE) Adeno_hexon_C PF03678.9 KEG08894.1 - 0.23 10.9 1.5 0.97 8.8 0.0 2.0 2 0 0 2 2 2 0 Hexon, adenovirus major coat protein, C-terminal domain ApoL PF05461.6 KEG08894.1 - 0.27 10.4 2.9 0.45 9.7 2.0 1.3 1 0 0 1 1 1 0 Apolipoprotein L Peroxin-13_N PF04088.8 KEG08894.1 - 0.32 10.9 4.0 0.37 10.7 1.7 1.9 1 1 1 2 2 2 0 Peroxin 13, N-terminal region DUF4263 PF14082.1 KEG08899.1 - 0.039 13.9 0.6 1.7 8.5 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4263) NTP_transf_2 PF01909.18 KEG08901.1 - 2.6e-05 24.4 0.0 9.9e-05 22.5 0.0 2.1 2 1 0 2 2 2 1 Nucleotidyltransferase domain FG-GAP PF01839.18 KEG08902.1 - 0.017 14.7 2.0 0.033 13.9 0.1 2.4 2 0 0 2 2 2 0 FG-GAP repeat CD99L2 PF12301.3 KEG08902.1 - 0.085 12.5 0.2 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 CD99 antigen like protein 2 Kinesin PF00225.18 KEG08904.1 - 2.5e-53 180.9 0.0 2.9e-53 180.7 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Bac_DnaA PF00308.13 KEG08904.1 - 0.029 14.0 0.1 0.22 11.1 0.0 2.0 2 0 0 2 2 2 0 Bacterial dnaA protein T2SE PF00437.15 KEG08904.1 - 0.029 13.2 0.0 0.062 12.1 0.0 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein DEAD PF00270.24 KEG08904.1 - 0.055 12.9 0.0 0.11 11.9 0.0 1.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_22 PF13401.1 KEG08904.1 - 0.084 13.0 0.2 0.42 10.7 0.2 2.0 2 0 0 2 2 2 0 AAA domain Kinesin PF00225.18 KEG08905.1 - 1.1e-19 70.4 0.2 2.8e-19 69.0 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain DUF1192 PF06698.6 KEG08905.1 - 0.016 14.9 0.9 0.84 9.4 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) WEMBL PF05701.6 KEG08905.1 - 0.15 10.4 15.1 0.011 14.2 4.7 2.1 2 0 0 2 2 2 0 Weak chloroplast movement under blue light zf-MYND PF01753.13 KEG08906.1 - 1e-11 44.4 7.3 1e-11 44.4 5.0 1.9 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.1 KEG08906.1 - 0.089 12.6 1.8 0.22 11.4 1.2 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Sld5 PF05916.6 KEG08907.1 - 5e-05 23.5 0.0 6.8e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein DEDD_Tnp_IS110 PF01548.12 KEG08907.1 - 0.049 13.2 0.0 0.1 12.2 0.0 1.5 1 1 0 1 1 1 0 Transposase CENP-C_mid PF15620.1 KEG08908.1 - 0.12 12.1 0.3 0.17 11.5 0.2 1.2 1 0 0 1 1 1 0 Centromere assembly component CENP-C middle DNMT3B-binding region Totivirus_coat PF05518.6 KEG08909.1 - 0.066 11.0 0.0 0.077 10.8 0.0 1.0 1 0 0 1 1 1 0 Totivirus coat protein PLAC8 PF04749.12 KEG08911.1 - 9.4e-12 45.4 23.6 9.4e-12 45.4 16.3 1.4 2 0 0 2 2 2 1 PLAC8 family PLAC8 PF04749.12 KEG08912.1 - 3.8e-10 40.2 26.4 3.8e-10 40.2 18.3 1.4 2 0 0 2 2 2 1 PLAC8 family Cpn60_TCP1 PF00118.19 KEG08913.1 - 2.2e-06 26.6 0.1 2.3e-06 26.5 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.19 KEG08914.1 - 3.5e-97 326.0 4.9 4.5e-97 325.6 3.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MutS_V PF00488.16 KEG08915.1 - 1.3e-60 204.7 0.0 2.4e-60 203.8 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.15 KEG08915.1 - 1.6e-34 118.3 0.0 3.1e-34 117.3 0.0 1.5 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.13 KEG08915.1 - 1.8e-22 80.1 1.0 2.4e-17 63.3 0.1 2.3 2 0 0 2 2 2 2 MutS domain III MutS_IV PF05190.13 KEG08915.1 - 4.4e-06 26.7 0.0 9.6e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.1 KEG08915.1 - 0.0066 15.9 0.0 0.018 14.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KEG08915.1 - 0.008 16.4 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_25 PF13481.1 KEG08915.1 - 0.049 13.0 0.0 0.18 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain KNOX2 PF03791.8 KEG08915.1 - 3.1 7.1 5.6 14 5.0 0.0 3.4 4 0 0 4 4 4 0 KNOX2 domain PLAC8 PF04749.12 KEG08916.1 - 3.2e-13 50.1 16.1 4e-13 49.8 11.2 1.1 1 0 0 1 1 1 1 PLAC8 family LicD PF04991.8 KEG08917.1 - 5.6e-11 42.9 1.4 1.9e-10 41.2 0.0 2.3 3 0 0 3 3 3 1 LicD family Exo_endo_phos PF03372.18 KEG08918.1 - 1.5e-15 57.8 0.0 7e-15 55.6 0.0 2.1 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Aldo_ket_red PF00248.16 KEG08919.1 - 0.0028 16.5 0.0 0.096 11.4 0.0 2.4 2 1 0 2 2 2 2 Aldo/keto reductase family HALZ PF02183.13 KEG08920.1 - 0.24 11.1 0.1 0.24 11.1 0.0 5.8 8 0 0 8 8 8 0 Homeobox associated leucine zipper Bd3614_N PF14442.1 KEG08921.1 - 0.2 11.6 4.5 0.12 12.3 1.3 1.9 2 0 0 2 2 2 0 Bd3614-like deaminase N-terminal Fer2 PF00111.22 KEG08922.1 - 1.7e-13 50.0 0.3 2.6e-13 49.5 0.2 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.1 KEG08922.1 - 0.91 9.3 4.0 0.66 9.8 0.6 2.4 3 1 0 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain RRM_1 PF00076.17 KEG08923.1 - 5.5e-08 32.3 0.0 8.7e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG08923.1 - 4e-07 29.9 0.0 5.9e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG08923.1 - 2.8e-05 23.8 0.0 4.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Btz PF09405.5 KEG08923.1 - 0.042 13.8 0.0 0.053 13.5 0.0 1.2 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding Kinesin PF00225.18 KEG08924.1 - 1.3e-09 37.2 0.1 3.3e-09 35.8 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain DUF1455 PF07306.6 KEG08924.1 - 0.05 13.6 0.1 0.074 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1455) TMF_DNA_bd PF12329.3 KEG08925.1 - 0.03 14.1 1.7 0.07 12.9 1.2 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF3445 PF11927.3 KEG08925.1 - 0.082 12.2 0.1 0.099 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3445) Vps39_2 PF10367.4 KEG08925.1 - 0.16 12.1 3.3 0.15 12.2 1.4 1.6 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Zn_ribbon_recom PF13408.1 KEG08926.1 - 0.078 13.2 0.2 0.14 12.4 0.1 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain DnaJ PF00226.26 KEG08927.1 - 2.4e-08 33.5 0.0 4.4e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain DEAD PF00270.24 KEG08928.1 - 3e-08 33.3 0.0 7.4e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEG08928.1 - 1.3e-07 31.4 0.3 4.5e-07 29.6 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HA2 PF04408.18 KEG08928.1 - 2.8e-05 24.0 0.4 0.00076 19.4 0.0 3.0 2 1 0 2 2 2 1 Helicase associated domain (HA2) AAA_22 PF13401.1 KEG08928.1 - 0.016 15.3 0.0 0.082 13.0 0.0 2.3 1 0 0 1 1 1 0 AAA domain Cupin_4 PF08007.7 KEG08929.1 - 5e-42 144.2 0.6 1.1e-41 143.1 0.4 1.6 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.1 KEG08929.1 - 3.2e-08 33.4 0.0 2.6e-07 30.3 0.0 2.0 1 1 0 1 1 1 1 Cupin-like domain 2OG-FeII_Oxy_2 PF13532.1 KEG08931.1 - 4.5e-07 29.8 0.0 5.5e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily APG12 PF04110.8 KEG08932.1 - 1.9e-05 24.7 0.0 2.2e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 DUF179 PF02622.10 KEG08933.1 - 2.1e-05 24.2 0.0 0.0021 17.7 0.0 2.5 3 0 0 3 3 3 2 Uncharacterized ACR, COG1678 WD40 PF00400.27 KEG08934.1 - 2.7e-57 188.7 24.2 1.1e-11 44.1 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat DUF1513 PF07433.6 KEG08934.1 - 1.2e-05 24.4 0.0 0.16 10.8 0.0 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF1513) Nup160 PF11715.3 KEG08934.1 - 1.4e-05 23.5 10.0 0.0029 15.8 0.1 4.4 2 2 2 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.6 KEG08934.1 - 7.4e-05 22.5 0.1 0.29 10.8 0.0 2.7 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 KEG08934.1 - 0.0068 16.0 0.3 6.5 6.5 0.0 4.0 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat MMS1_N PF10433.4 KEG08934.1 - 0.056 11.5 0.0 1.3 7.0 0.0 2.4 2 1 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Cytochrom_D1 PF02239.11 KEG08934.1 - 0.066 11.5 0.0 0.72 8.0 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain AAA PF00004.24 KEG08935.1 - 2.4e-10 40.7 0.0 2.9e-08 33.9 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEG08935.1 - 0.046 13.6 0.1 0.16 11.9 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 KEG08935.1 - 0.049 14.4 0.0 0.16 12.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain Spc97_Spc98 PF04130.8 KEG08936.1 - 1.2e-76 258.2 0.1 1.8e-76 257.5 0.1 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family SMC_Nse1 PF07574.8 KEG08937.1 - 1.1 8.8 7.6 0.16 11.5 0.2 2.6 1 1 1 3 3 3 0 Nse1 non-SMC component of SMC5-6 complex MRP-S26 PF14943.1 KEG08937.1 - 1.4 8.4 16.0 1.1 8.8 3.1 2.6 2 1 1 3 3 3 0 Mitochondrial ribosome subunit S26 PTPlike_phytase PF14566.1 KEG08937.1 - 3 7.9 8.3 6.2 6.8 0.9 3.2 1 1 2 3 3 3 0 Inositol hexakisphosphate SBDS_C PF09377.5 KEG08937.1 - 5.1 6.8 9.2 3.3 7.4 0.3 2.4 2 0 0 2 2 2 0 SBDS protein C-terminal domain AATF-Che1 PF13339.1 KEG08937.1 - 5.2 7.2 17.7 0.67 10.1 0.9 2.9 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Mucin PF01456.12 KEG08941.1 - 0.0022 17.7 0.1 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein Pkinase PF00069.20 KEG08944.1 - 3.5e-56 190.2 0.0 4.1e-56 190.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG08944.1 - 9.1e-31 106.8 0.0 1.2e-30 106.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG08944.1 - 9.1e-05 21.5 0.0 0.00018 20.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEG08944.1 - 0.045 13.4 0.0 0.21 11.3 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family HA2 PF04408.18 KEG08945.1 - 3.7e-18 65.4 0.1 1.3e-17 63.6 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KEG08945.1 - 3.8e-14 52.4 0.0 1.2e-13 50.9 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KEG08945.1 - 1.7e-13 50.2 0.0 4.6e-13 48.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEG08945.1 - 1.2e-09 37.8 0.0 2.5e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KEG08945.1 - 5.2e-05 23.3 0.2 0.00022 21.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain Miro PF08477.8 KEG08945.1 - 0.0026 18.2 0.7 0.066 13.7 0.0 2.8 3 0 0 3 3 2 1 Miro-like protein AAA_23 PF13476.1 KEG08945.1 - 0.0088 16.3 0.1 0.0088 16.3 0.1 2.6 1 1 2 3 3 2 1 AAA domain AAA_19 PF13245.1 KEG08945.1 - 0.011 15.4 0.0 0.043 13.5 0.0 2.0 1 1 0 1 1 1 0 Part of AAA domain T2SE PF00437.15 KEG08945.1 - 0.015 14.2 2.6 0.035 13.0 1.8 1.6 1 1 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.14 KEG08945.1 - 0.015 14.7 1.3 0.57 9.6 0.0 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 KEG08945.1 - 0.018 14.7 0.0 0.044 13.4 0.0 1.7 1 0 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 KEG08945.1 - 0.024 14.5 0.0 0.32 10.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KEG08945.1 - 0.025 14.0 0.1 0.061 12.7 0.0 1.7 1 1 0 1 1 1 0 FtsK/SpoIIIE family AAA_10 PF12846.2 KEG08945.1 - 0.025 14.0 0.0 2.2 7.6 0.0 2.7 3 0 0 3 3 3 0 AAA-like domain KaiC PF06745.8 KEG08945.1 - 0.04 13.0 0.1 0.12 11.5 0.0 1.8 1 1 0 1 1 1 0 KaiC ResIII PF04851.10 KEG08945.1 - 0.044 13.6 0.2 0.82 9.4 0.0 2.4 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit ABC_tran PF00005.22 KEG08945.1 - 0.051 13.8 0.1 0.27 11.5 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_25 PF13481.1 KEG08945.1 - 0.056 12.8 0.0 0.16 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.7 KEG08945.1 - 0.13 11.5 0.0 0.97 8.6 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_29 PF13555.1 KEG08945.1 - 0.17 11.4 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NifU PF01106.12 KEG08946.1 - 5.3e-19 67.7 0.0 1e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.6 KEG08946.1 - 3.2e-08 33.0 0.0 7.1e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal eIF-6 PF01912.13 KEG08947.1 - 1.4e-82 275.6 0.2 1.9e-82 275.1 0.1 1.2 1 0 0 1 1 1 1 eIF-6 family Pkinase PF00069.20 KEG08948.1 - 4.2e-73 245.6 0.0 6.1e-73 245.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG08948.1 - 5.5e-39 133.8 0.0 8.7e-39 133.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG08948.1 - 6.8e-05 21.9 0.2 0.00031 19.8 0.0 2.1 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.9 KEG08948.1 - 0.0015 17.6 0.3 0.0033 16.4 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Tmemb_9 PF05434.6 KEG08949.1 - 0.0097 15.6 5.2 0.0097 15.6 3.6 1.3 1 1 0 1 1 1 1 TMEM9 Glycophorin_A PF01102.13 KEG08949.1 - 0.092 12.5 0.0 0.095 12.4 0.0 1.1 1 0 0 1 1 1 0 Glycophorin A zf-RING_3 PF14369.1 KEG08949.1 - 0.14 12.1 3.3 0.3 11.1 2.3 1.6 1 0 0 1 1 1 0 zinc-finger ACC_epsilon PF13822.1 KEG08950.1 - 0.49 10.7 0.1 0.49 10.7 0.0 3.0 2 1 1 3 3 3 0 Acyl-CoA carboxylase epsilon subunit DUF566 PF04484.7 KEG08950.1 - 2.6 7.4 7.3 3.3 7.1 5.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Kinesin PF00225.18 KEG08955.1 - 2.8e-86 289.2 0.0 7e-83 278.1 0.0 2.2 1 1 0 1 1 1 1 Kinesin motor domain Wyosine_form PF08608.7 KEG08956.1 - 1.7e-21 76.0 0.4 5.6e-15 55.2 0.0 2.8 2 0 0 2 2 2 2 Wyosine base formation Radical_SAM PF04055.16 KEG08956.1 - 6.4e-14 52.4 0.0 1.1e-13 51.7 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily DUF2366 PF10171.4 KEG08956.1 - 0.078 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2366) DUF3588 PF12140.3 KEG08956.1 - 0.092 12.8 0.1 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3588) DUF4620 PF15399.1 KEG08957.1 - 0.42 10.7 4.3 0.15 12.2 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4620) Vma12 PF11712.3 KEG08959.1 - 0.00095 18.8 0.0 0.0025 17.5 0.0 1.7 2 0 0 2 2 2 1 Endoplasmic reticulum-based factor for assembly of V-ATPase SAC3_GANP PF03399.11 KEG08960.1 - 0.003 17.1 0.3 0.0046 16.5 0.2 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DUF4180 PF13788.1 KEG08961.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4180) DUF3638 PF12340.3 KEG08962.1 - 7.2e-28 97.1 0.2 1.2e-23 83.3 0.3 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3638) DUF3645 PF12359.3 KEG08962.1 - 5.1e-18 63.9 0.3 1.2e-17 62.6 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) zf-RanBP PF00641.13 KEG08962.1 - 0.00025 20.0 25.1 0.00084 18.3 2.6 4.0 3 1 0 3 3 3 2 Zn-finger in Ran binding protein and others DZR PF12773.2 KEG08962.1 - 1.8 8.4 18.9 0.34 10.7 8.6 2.8 2 0 0 2 2 2 0 Double zinc ribbon Actin PF00022.14 KEG08963.1 - 9.6e-101 337.0 0.0 1.1e-100 336.8 0.0 1.0 1 0 0 1 1 1 1 Actin CHCH PF06747.8 KEG08964.1 - 5.9e-07 29.2 1.4 1.1e-06 28.3 1.0 1.5 1 1 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 KEG08964.1 - 0.006 16.3 0.8 0.014 15.1 0.6 1.6 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.8 KEG08964.1 - 0.0076 16.2 2.4 0.1 12.6 0.3 2.4 1 1 1 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) COX6B PF02297.12 KEG08964.1 - 0.048 13.6 0.7 0.094 12.7 0.5 1.5 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 KEG08964.1 - 0.062 13.3 2.4 0.16 11.9 1.7 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 DUF1903 PF08991.5 KEG08964.1 - 0.09 12.9 2.3 0.17 12.0 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1903) Fez1 PF06818.10 KEG08967.1 - 0.024 14.6 0.5 0.024 14.6 0.4 3.1 3 0 0 3 3 3 0 Fez1 Cep57_CLD_2 PF14197.1 KEG08967.1 - 0.048 13.5 4.0 8.7 6.3 0.0 3.5 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 DUF2422 PF10337.4 KEG08967.1 - 0.15 10.8 0.6 0.6 8.8 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2422) TMF_TATA_bd PF12325.3 KEG08967.1 - 0.52 10.0 8.8 4.5 7.0 0.0 3.5 4 0 0 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF4463 PF14703.1 KEG08967.1 - 0.91 10.0 4.5 49 4.5 0.2 4.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4463) CENP-F_leu_zip PF10473.4 KEG08967.1 - 1.3 8.8 9.8 1.5 8.6 0.7 3.9 4 0 0 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GED PF02212.13 KEG08967.1 - 3.8 7.4 5.7 12 5.8 1.7 2.6 2 0 0 2 2 2 0 Dynamin GTPase effector domain IPK PF03770.11 KEG08971.1 - 9.7e-43 146.1 0.0 2e-42 145.0 0.0 1.5 1 0 0 1 1 1 1 Inositol polyphosphate kinase U79_P34 PF03064.11 KEG08971.1 - 2.5 7.5 12.0 0.18 11.2 4.8 1.6 2 0 0 2 2 2 0 HSV U79 / HCMV P34 Thr_synth_N PF14821.1 KEG08972.1 - 1.8e-11 43.9 0.0 4.8e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 KEG08972.1 - 2.6e-08 33.4 0.0 3.6e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DEAD PF00270.24 KEG08973.1 - 2.5e-07 30.3 0.1 3.3e-07 29.9 0.1 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase T4SS-DNA_transf PF02534.9 KEG08973.1 - 0.041 12.4 0.0 0.043 12.4 0.0 1.1 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer AAA_19 PF13245.1 KEG08973.1 - 0.049 13.3 0.6 0.23 11.2 0.3 1.9 2 0 0 2 2 2 0 Part of AAA domain ResIII PF04851.10 KEG08973.1 - 0.15 11.8 0.0 0.15 11.8 0.0 1.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit MFS_1 PF07690.11 KEG08974.1 - 6.7e-19 67.8 47.1 1.1e-09 37.5 18.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEG08974.1 - 8e-08 31.2 25.8 0.00025 19.7 4.2 3.2 2 1 1 3 3 3 3 Sugar (and other) transporter AAA PF00004.24 KEG08975.1 - 9.2e-44 148.8 0.0 2e-43 147.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KEG08975.1 - 1.1e-07 31.2 0.0 1.9e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KEG08975.1 - 1.7e-05 24.9 0.0 0.031 14.4 0.0 3.5 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 KEG08975.1 - 0.00019 21.4 0.1 0.013 15.5 0.0 3.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 KEG08975.1 - 0.00024 21.0 0.0 0.00063 19.6 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 KEG08975.1 - 0.0017 19.1 0.0 0.0041 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KEG08975.1 - 0.0023 18.0 0.0 0.0071 16.5 0.0 1.9 2 0 0 2 2 1 1 RNA helicase AAA_5 PF07728.9 KEG08975.1 - 0.0028 17.3 0.0 0.008 15.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KEG08975.1 - 0.0029 17.5 0.0 0.014 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KEG08975.1 - 0.0042 16.5 0.0 0.012 15.0 0.0 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 KEG08975.1 - 0.0064 15.6 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 KEG08975.1 - 0.0075 16.1 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KEG08975.1 - 0.0089 15.2 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 KEG08975.1 - 0.012 15.0 0.1 0.39 10.0 0.0 2.9 2 1 0 3 3 3 0 AAA domain TIP49 PF06068.8 KEG08975.1 - 0.013 14.2 0.0 0.02 13.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_28 PF13521.1 KEG08975.1 - 0.016 15.1 0.0 0.048 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Vps4_C PF09336.5 KEG08975.1 - 0.02 14.7 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain Parvo_NS1 PF01057.12 KEG08975.1 - 0.021 13.6 0.0 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 KEG08975.1 - 0.029 14.4 0.0 6.2 6.8 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.22 KEG08975.1 - 0.067 13.4 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.1 KEG08975.1 - 0.068 13.4 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 KEG08975.1 - 0.14 11.0 0.0 0.38 9.6 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein SKI PF01202.17 KEG08975.1 - 0.15 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase PhoH PF02562.11 KEG08975.1 - 0.18 11.0 0.0 0.36 10.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein KaiC PF06745.8 KEG08975.1 - 0.19 10.8 0.0 0.41 9.7 0.0 1.5 1 0 0 1 1 1 0 KaiC DUF815 PF05673.8 KEG08975.1 - 0.22 10.4 0.0 0.37 9.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 KEG08975.1 - 0.26 10.8 0.1 0.49 9.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Myb_DNA-binding PF00249.26 KEG08976.1 - 0.072 13.1 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Kelch_3 PF13415.1 KEG08977.1 - 4.6e-30 103.0 5.9 1.1e-06 28.6 0.0 7.0 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.1 KEG08977.1 - 3.4e-28 97.1 6.9 9.3e-06 25.3 0.0 6.8 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 KEG08977.1 - 7e-26 89.7 3.4 1.1e-05 25.2 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 KEG08977.1 - 4.4e-19 67.7 5.9 0.012 15.7 0.0 6.4 5 1 1 6 6 6 5 Kelch motif DUF4110 PF13422.1 KEG08977.1 - 5.7e-17 61.3 11.7 5.7e-17 61.3 8.1 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4110) Kelch_1 PF01344.20 KEG08977.1 - 5.7e-15 54.5 11.0 0.0015 18.0 0.0 6.8 6 1 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 KEG08977.1 - 1.7e-10 40.2 9.1 0.56 10.0 0.0 6.5 6 1 0 6 6 6 4 Kelch motif GLE1 PF07817.8 KEG08977.1 - 0.13 11.1 0.5 0.29 10.0 0.0 1.7 2 0 0 2 2 2 0 GLE1-like protein Tetraspannin PF00335.15 KEG08978.1 - 0.017 14.3 0.3 0.02 14.2 0.2 1.1 1 0 0 1 1 1 0 Tetraspanin family CD20 PF04103.10 KEG08978.1 - 0.023 14.6 0.2 0.049 13.5 0.0 1.5 2 0 0 2 2 2 0 CD20-like family Pkinase PF00069.20 KEG08979.1 - 4.1e-75 252.2 0.0 5.2e-75 251.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG08979.1 - 3.2e-39 134.5 0.0 4.2e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG08979.1 - 5.8e-09 35.3 0.0 8.2e-09 34.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEG08979.1 - 0.00021 21.0 0.0 0.035 13.8 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 KEG08979.1 - 0.0026 17.1 0.1 0.0051 16.1 0.0 1.4 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 KEG08979.1 - 0.0071 14.9 0.1 0.0096 14.5 0.0 1.1 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Choline_kinase PF01633.15 KEG08979.1 - 0.042 13.4 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 KEG08979.1 - 0.046 12.7 0.0 0.082 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KEG08980.1 - 1.1e-75 254.1 0.0 1.3e-75 253.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG08980.1 - 2.4e-40 138.2 0.0 2.9e-40 138.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG08980.1 - 4e-10 39.1 0.0 7.2e-10 38.2 0.0 1.4 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KEG08980.1 - 0.0074 15.3 0.1 0.013 14.5 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEG08980.1 - 0.013 15.2 0.1 1.4 8.6 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF421 PF04239.7 KEG08980.1 - 0.017 14.6 0.5 0.044 13.3 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF421) Pkinase PF00069.20 KEG08981.1 - 2e-75 253.2 0.0 2.3e-75 253.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG08981.1 - 3.7e-41 140.9 0.0 4.3e-41 140.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG08981.1 - 1.2e-12 47.4 0.0 2.1e-12 46.6 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KEG08981.1 - 2.5e-05 24.1 0.1 0.13 11.9 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KEG08981.1 - 0.00031 19.8 0.3 0.00053 19.1 0.2 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KEG08981.1 - 0.00047 19.5 0.1 0.00077 18.8 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.6 KEG08981.1 - 0.0044 15.8 0.1 0.008 15.0 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase PF00069.20 KEG08982.1 - 1.7e-76 256.7 0.0 1.9e-76 256.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG08982.1 - 2.9e-41 141.2 0.0 3.5e-41 141.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG08982.1 - 1.5e-09 37.2 0.0 2.1e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEG08982.1 - 0.001 18.8 0.1 1.4 8.6 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KEG08982.1 - 0.0068 15.5 0.1 0.013 14.6 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Phosducin PF02114.11 KEG08982.1 - 0.019 13.7 0.0 0.026 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosducin DUF421 PF04239.7 KEG08982.1 - 0.31 10.5 1.4 0.75 9.3 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF421) Ribosomal_L1 PF00687.16 KEG08984.1 - 8e-46 156.1 3.2 9.1e-46 155.9 2.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family U1snRNP70_N PF12220.3 KEG08984.1 - 0.28 11.5 2.8 0.91 9.8 0.1 2.3 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Ribosomal_S27e PF01667.12 KEG08985.1 - 4.6e-24 83.7 4.3 5.9e-24 83.3 3.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 KEG08985.1 - 0.00049 19.9 2.0 0.00059 19.6 1.4 1.2 1 0 0 1 1 1 1 IBR domain Elf1 PF05129.8 KEG08985.1 - 0.084 12.5 1.6 0.12 12.0 1.1 1.2 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.2 KEG08985.1 - 0.086 12.6 0.9 0.12 12.1 0.6 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain TF_Zn_Ribbon PF08271.7 KEG08985.1 - 0.088 12.1 1.2 0.14 11.4 0.9 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding FYVE_2 PF02318.11 KEG08985.1 - 0.14 12.0 0.8 0.17 11.8 0.6 1.1 1 0 0 1 1 1 0 FYVE-type zinc finger zinc_ribbon_4 PF13717.1 KEG08985.1 - 0.15 11.8 2.8 2.2 8.0 2.0 2.4 1 1 0 1 1 1 0 zinc-ribbon domain Yippee-Mis18 PF03226.9 KEG08985.1 - 0.27 11.3 2.9 3.4 7.7 0.0 2.1 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Zn_Tnp_IS1 PF03811.8 KEG08985.1 - 0.28 10.6 4.8 1.3 8.5 3.3 2.1 1 1 0 1 1 1 0 InsA N-terminal domain zinc_ribbon_5 PF13719.1 KEG08985.1 - 0.3 10.6 3.2 3.9 7.1 2.2 2.3 1 1 0 1 1 1 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 KEG08985.1 - 0.75 9.4 3.4 0.61 9.7 1.6 1.5 1 1 0 1 1 1 0 Putative transposase DNA-binding domain Mu-like_Com PF10122.4 KEG08985.1 - 1.1 8.4 4.6 1.4 8.0 0.1 2.3 1 1 1 2 2 2 0 Mu-like prophage protein Com zf-LSD1 PF06943.7 KEG08985.1 - 4.2 7.0 6.9 15 5.2 0.0 3.1 3 0 0 3 3 3 0 LSD1 zinc finger TFIIS_C PF01096.13 KEG08986.1 - 3.2e-12 45.8 8.0 3.2e-12 45.8 5.5 3.5 4 0 0 4 4 4 1 Transcription factor S-II (TFIIS) PI3K_1B_p101 PF10486.4 KEG08986.1 - 0.015 12.9 0.2 0.019 12.5 0.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit UreF PF01730.11 KEG08986.1 - 0.083 13.0 2.7 0.081 13.0 1.2 1.5 1 1 0 1 1 1 0 UreF Rpr2 PF04032.11 KEG08986.1 - 0.22 11.4 11.3 34 4.4 6.0 2.5 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-ribbon_3 PF13248.1 KEG08986.1 - 0.47 9.7 0.1 0.47 9.7 0.0 3.2 4 0 0 4 4 4 0 zinc-ribbon domain Stc1 PF12898.2 KEG08986.1 - 3.9 7.5 20.3 0.2 11.7 5.1 2.7 1 1 1 2 2 2 0 Stc1 domain zf-CHY PF05495.7 KEG08986.1 - 6.9 6.9 20.5 0.91 9.7 5.5 2.8 2 1 0 2 2 2 0 CHY zinc finger Zn_ribbon_recom PF13408.1 KEG08986.1 - 7.1 6.9 14.8 8.7 6.6 2.5 2.5 2 1 1 3 3 3 0 Recombinase zinc beta ribbon domain Lipase_GDSL_2 PF13472.1 KEG08987.1 - 0.049 13.7 1.8 0.13 12.3 0.0 2.5 4 0 0 4 4 4 0 GDSL-like Lipase/Acylhydrolase family IQ PF00612.22 KEG08987.1 - 0.067 12.8 2.2 0.084 12.5 0.1 2.3 2 0 0 2 2 2 0 IQ calmodulin-binding motif Nop14 PF04147.7 KEG08988.1 - 0.0031 15.5 6.4 0.0041 15.1 4.4 1.1 1 0 0 1 1 1 1 Nop14-like family NOA36 PF06524.7 KEG08988.1 - 0.0052 16.0 3.0 0.0073 15.6 2.1 1.2 1 0 0 1 1 1 1 NOA36 protein CDC45 PF02724.9 KEG08988.1 - 0.011 13.8 2.7 0.013 13.5 1.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 KEG08988.1 - 0.015 14.8 3.4 0.023 14.2 2.4 1.4 1 0 0 1 1 1 0 Nucleoplasmin eIF-3c_N PF05470.7 KEG08988.1 - 0.097 10.7 1.2 0.13 10.3 0.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Bd3614_N PF14442.1 KEG08988.1 - 0.51 10.3 7.1 1.5 8.8 4.9 1.8 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal EBV-NA3 PF05009.7 KEG08988.1 - 1.4 8.1 4.2 2.3 7.3 2.9 1.4 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Paf1 PF03985.8 KEG08988.1 - 1.4 7.5 8.6 2.1 6.9 5.9 1.1 1 0 0 1 1 1 0 Paf1 TRAP_alpha PF03896.11 KEG08988.1 - 2.5 7.0 5.1 4 6.3 3.6 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4611 PF15387.1 KEG08988.1 - 2.5 8.2 13.5 0.42 10.7 0.9 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) Sigma70_ner PF04546.8 KEG08988.1 - 2.6 7.6 10.1 4.3 6.8 7.0 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region FAM176 PF14851.1 KEG08988.1 - 4.6 6.9 5.8 1.6 8.4 2.2 1.7 2 0 0 2 2 2 0 FAM176 family Glycos_transf_4 PF00953.16 KEG08989.1 - 7.9e-40 136.2 5.6 7.9e-40 136.2 3.9 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 4 HSA PF07529.8 KEG08989.1 - 0.14 12.0 0.2 1.1 9.1 0.0 2.2 3 0 0 3 3 3 0 HSA Sld5 PF05916.6 KEG08990.1 - 1e-14 54.7 0.0 1.6e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Med3 PF11593.3 KEG08990.1 - 0.074 12.2 3.2 0.088 12.0 2.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Arrestin_N PF00339.24 KEG08991.1 - 1.1e-09 38.2 3.3 4.7e-09 36.2 0.0 2.7 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 KEG08991.1 - 0.091 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Arrestin_N terminal like U79_P34 PF03064.11 KEG08991.1 - 0.1 12.0 14.8 0.19 11.1 10.2 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Cas_Csy4 PF09618.5 KEG08991.1 - 0.16 11.8 2.8 0.24 11.1 2.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) Paf1 PF03985.8 KEG08991.1 - 0.54 8.9 10.4 0.85 8.2 7.2 1.2 1 0 0 1 1 1 0 Paf1 Rgp1 PF08737.5 KEG08991.1 - 6.7 5.6 8.6 0.99 8.4 0.3 2.5 3 0 0 3 3 3 0 Rgp1 Skp1 PF01466.14 KEG08993.1 - 0.017 15.1 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Skp1 family, dimerisation domain NGP1NT PF08153.7 KEG08994.1 - 3.3e-44 149.9 0.7 3.3e-44 149.9 0.5 1.8 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 KEG08994.1 - 1.3e-19 70.2 0.4 8.5e-16 57.9 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 KEG08994.1 - 6e-05 22.3 0.1 0.00015 21.0 0.1 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KEG08994.1 - 7.9e-05 22.5 6.4 0.3 10.8 0.0 4.2 3 2 1 4 4 4 2 Dynamin family GTP_EFTU PF00009.22 KEG08994.1 - 0.0011 18.4 0.2 1.3 8.4 0.0 3.6 4 0 0 4 4 4 1 Elongation factor Tu GTP binding domain Miro PF08477.8 KEG08994.1 - 0.0015 19.0 0.2 0.56 10.7 0.0 3.2 2 0 0 2 2 2 1 Miro-like protein DUF258 PF03193.11 KEG08994.1 - 0.0034 16.5 0.0 0.0078 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KEG08994.1 - 0.048 13.6 0.0 0.14 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain MobB PF03205.9 KEG08994.1 - 0.049 13.3 0.2 0.28 10.9 0.1 2.2 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MFS_1 PF07690.11 KEG08995.1 - 3.9e-31 108.0 48.6 1.5e-24 86.4 13.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP-synt_ab PF00006.20 KEG08997.1 - 6e-69 231.8 0.1 9.6e-69 231.1 0.1 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KEG08997.1 - 0.011 16.1 0.1 0.033 14.6 0.0 1.8 2 0 0 2 2 2 0 ATP synthase alpha/beta chain, C terminal domain ADH_N PF08240.7 KEG08998.1 - 6.7e-05 22.6 1.1 0.00035 20.2 0.1 2.3 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEG08999.1 - 1.4e-05 24.6 0.2 2e-05 24.1 0.1 1.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase DUF4407 PF14362.1 KEG09000.1 - 3 6.7 19.9 7.3 5.4 13.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RRM_1 PF00076.17 KEG09001.1 - 3.9e-14 52.0 0.0 5.4e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG09001.1 - 1.9e-10 40.5 0.0 2.5e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG09001.1 - 1.8e-07 30.8 0.0 3.2e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TSKS PF15358.1 KEG09001.1 - 0.019 13.1 0.2 0.02 13.0 0.1 1.0 1 0 0 1 1 1 0 Testis-specific serine kinase substrate RNA_bind PF08675.6 KEG09001.1 - 0.047 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 RNA binding domain Suf PF05843.9 KEG09001.1 - 0.36 10.5 3.5 0.41 10.3 2.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RIH_assoc PF08454.6 KEG09002.1 - 8.1e-31 105.9 0.5 2.4e-30 104.3 0.4 1.8 1 0 0 1 1 1 1 RyR and IP3R Homology associated Ion_trans PF00520.26 KEG09002.1 - 8.8e-09 34.9 12.8 8.8e-09 34.9 8.8 2.5 3 0 0 3 3 3 1 Ion transport protein Med3 PF11593.3 KEG09002.1 - 0.55 9.4 2.8 1 8.5 1.9 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ins145_P3_rec PF08709.6 KEG09003.1 - 7e-37 126.5 0.0 1.6e-36 125.3 0.0 1.6 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor RYDR_ITPR PF01365.16 KEG09003.1 - 1.2e-10 40.9 0.4 3.5e-09 36.1 0.3 2.7 1 1 0 1 1 1 1 RIH domain ATG16 PF08614.6 KEG09004.1 - 0.00016 21.5 8.3 0.00016 21.5 5.8 2.5 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) DUF4407 PF14362.1 KEG09004.1 - 0.003 16.5 1.9 0.003 16.5 1.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4407) APG6 PF04111.7 KEG09004.1 - 0.003 16.6 20.1 0.091 11.7 1.9 2.2 2 0 0 2 2 2 2 Autophagy protein Apg6 FemAB PF02388.11 KEG09004.1 - 0.12 11.0 4.3 0.21 10.2 3.0 1.3 1 0 0 1 1 1 0 FemAB family TBPIP PF07106.8 KEG09004.1 - 0.27 10.7 11.7 0.91 9.0 3.4 2.7 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CENP-K PF11802.3 KEG09004.1 - 0.51 9.5 9.9 0.24 10.5 1.6 2.5 2 0 0 2 2 2 0 Centromere-associated protein K Ras PF00071.17 KEG09005.1 - 1.4e-58 196.8 0.0 1.7e-58 196.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEG09005.1 - 8e-18 65.0 0.0 1.2e-17 64.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEG09005.1 - 2e-14 53.2 0.0 2.3e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KEG09005.1 - 4.1e-07 29.6 0.0 1.6e-05 24.4 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KEG09005.1 - 0.00035 20.5 0.0 0.00051 19.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KEG09005.1 - 0.004 16.3 0.0 0.0049 16.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 KEG09005.1 - 0.042 13.3 0.0 0.081 12.4 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Pkinase PF00069.20 KEG09006.1 - 3.7e-43 147.5 0.0 2.7e-41 141.4 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG09006.1 - 6.6e-24 84.3 0.0 4.3e-23 81.7 0.0 2.1 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG09006.1 - 0.16 10.8 0.0 0.71 8.7 0.0 2.0 2 0 0 2 2 2 0 Kinase-like CH PF00307.26 KEG09007.1 - 0.00071 19.5 0.0 0.00088 19.2 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain zf-C2H2_4 PF13894.1 KEG09008.1 - 3.9e-09 36.1 33.3 0.0004 20.5 1.4 5.8 5 1 1 6 6 6 4 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KEG09008.1 - 3.9e-06 26.8 2.1 3.9e-06 26.8 1.5 6.7 7 1 0 7 7 7 2 Zinc-finger double domain zf-BED PF02892.10 KEG09008.1 - 0.0004 20.0 16.1 0.054 13.2 0.0 4.8 5 1 1 6 6 6 2 BED zinc finger Sgf11 PF08209.6 KEG09008.1 - 0.0025 17.0 0.3 0.078 12.3 0.0 2.9 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-C2H2 PF00096.21 KEG09008.1 - 0.28 11.6 0.2 0.077 13.3 1.1 5.7 6 0 0 6 6 6 0 Zinc finger, C2H2 type MSP1_C PF07462.6 KEG09008.1 - 0.28 9.5 0.1 0.43 8.9 0.1 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF629 PF04780.7 KEG09008.1 - 0.38 9.2 1.4 14 4.0 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF629) zf-HYPF PF07503.7 KEG09008.1 - 0.54 9.7 7.0 0.51 9.7 0.1 3.1 3 0 0 3 3 3 0 HypF finger RNHCP PF12647.2 KEG09008.1 - 3.4 7.5 10.8 1.6 8.5 0.8 3.2 3 1 0 3 3 3 0 RNHCP domain DNA_binding_1 PF01035.15 KEG09009.1 - 1.2e-27 95.4 0.2 1.7e-27 94.9 0.1 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Cnd1 PF12717.2 KEG09010.1 - 0.0077 16.0 0.5 0.024 14.4 0.0 2.1 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Chromadorea_ALT PF05535.7 KEG09010.1 - 0.033 14.2 0.3 0.074 13.1 0.2 1.5 1 0 0 1 1 1 0 Chromadorea ALT protein HEAT PF02985.17 KEG09010.1 - 0.045 13.8 11.4 9.8 6.5 0.0 6.5 5 0 0 5 5 5 0 HEAT repeat FdhE PF04216.7 KEG09011.1 - 0.066 12.9 3.7 0.081 12.6 2.6 1.0 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Kinesin PF00225.18 KEG09012.1 - 2.5e-06 26.4 0.0 2e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 Kinesin motor domain COX17 PF05051.8 KEG09013.1 - 7.3e-06 25.9 0.4 1.1e-05 25.2 0.3 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Thiolase_C PF02803.13 KEG09014.1 - 1.5e-13 50.2 0.2 2.5e-12 46.3 0.1 2.5 1 1 1 2 2 2 1 Thiolase, C-terminal domain Thiolase_N PF00108.18 KEG09014.1 - 1e-08 34.4 0.1 3.1e-06 26.3 0.0 2.4 2 0 0 2 2 2 2 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 KEG09014.1 - 1.5e-06 27.9 4.9 3e-06 26.9 1.2 2.5 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 KEG09014.1 - 0.024 14.2 1.0 11 5.7 0.4 3.2 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.17 KEG09014.1 - 0.049 13.4 1.0 0.51 10.1 0.6 2.7 1 1 1 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain PriCT_2 PF08707.6 KEG09015.1 - 2e-14 53.1 5.2 4e-14 52.2 1.3 2.4 1 1 1 2 2 2 1 Primase C terminal 2 (PriCT-2) GFO_IDH_MocA PF01408.17 KEG09016.1 - 1.4e-06 28.8 0.0 2.8e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA PF01408.17 KEG09017.1 - 8.5e-13 48.8 0.0 1.6e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DIM1 PF02966.11 KEG09018.1 - 3.2e-34 117.3 0.0 9.2e-28 96.4 0.0 2.1 2 0 0 2 2 2 2 Mitosis protein DIM1 NeuB PF03102.9 KEG09019.1 - 0.15 11.1 0.0 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 NeuB family Tim17 PF02466.14 KEG09020.1 - 1.1e-16 61.0 8.1 1.3e-16 60.7 5.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family MRP PF09387.5 KEG09021.1 - 1.2e-67 227.3 1.4 1.5e-67 227.0 1.0 1.0 1 0 0 1 1 1 1 Mitochondrial RNA binding protein MRP DUF1737 PF08410.5 KEG09022.1 - 0.097 12.4 0.0 11 5.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1737) CALCOCO1 PF07888.6 KEG09023.1 - 0.0001 20.7 9.2 0.0021 16.4 3.4 2.0 2 0 0 2 2 2 2 Calcium binding and coiled-coil domain (CALCOCO1) like Tropomyosin PF00261.15 KEG09023.1 - 0.003 16.6 12.1 0.044 12.8 0.7 2.4 1 1 1 2 2 2 2 Tropomyosin Syntaxin-6_N PF09177.6 KEG09023.1 - 0.0045 17.3 3.3 0.016 15.5 0.6 2.5 2 1 0 2 2 2 1 Syntaxin 6, N-terminal EzrA PF06160.7 KEG09023.1 - 0.014 13.6 5.3 0.026 12.7 3.5 1.5 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA ADIP PF11559.3 KEG09023.1 - 0.017 15.0 1.9 0.017 15.0 1.3 2.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF3584 PF12128.3 KEG09023.1 - 0.023 12.0 7.4 0.032 11.6 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TBPIP PF07106.8 KEG09023.1 - 0.028 13.9 6.0 0.41 10.1 1.2 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF641 PF04859.7 KEG09023.1 - 0.028 14.1 6.6 0.038 13.7 0.1 2.6 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) Prefoldin_2 PF01920.15 KEG09023.1 - 0.038 13.7 6.5 3.6 7.4 0.0 3.5 3 1 0 3 3 3 0 Prefoldin subunit CENP-Q PF13094.1 KEG09023.1 - 0.045 13.7 11.8 0.15 12.0 1.4 2.3 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Filament PF00038.16 KEG09023.1 - 0.073 12.5 13.2 0.027 13.9 5.3 2.1 1 1 1 2 2 2 0 Intermediate filament protein Mnd1 PF03962.10 KEG09023.1 - 0.1 12.2 8.5 1.8 8.1 2.2 2.3 1 1 1 2 2 2 0 Mnd1 family Reo_sigmaC PF04582.7 KEG09023.1 - 0.11 11.6 3.3 4.7 6.2 0.1 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF3166 PF11365.3 KEG09023.1 - 0.13 12.7 4.1 3.5 8.1 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3166) Tropomyosin_1 PF12718.2 KEG09023.1 - 0.15 11.9 13.4 0.96 9.2 5.6 2.8 1 1 1 2 2 2 0 Tropomyosin like TPD52 PF04201.10 KEG09023.1 - 0.16 11.7 0.2 0.16 11.7 0.1 2.3 3 0 0 3 3 2 0 Tumour protein D52 family Rootletin PF15035.1 KEG09023.1 - 0.18 11.7 12.5 0.22 11.4 0.5 2.6 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF4071 PF13281.1 KEG09023.1 - 0.18 10.5 8.4 0.12 11.1 2.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4071) GAS PF13851.1 KEG09023.1 - 0.21 10.7 8.6 0.5 9.5 4.7 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding AAA_13 PF13166.1 KEG09023.1 - 0.26 9.7 4.2 0.6 8.5 2.9 1.5 1 1 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.7 KEG09023.1 - 0.27 11.0 3.6 1.4 8.7 1.3 2.5 2 1 0 2 2 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4456 PF14644.1 KEG09023.1 - 0.34 10.1 6.6 0.4 9.8 2.7 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4456) ALIX_LYPXL_bnd PF13949.1 KEG09023.1 - 0.4 9.5 8.9 0.14 11.1 3.9 1.8 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV DUF4407 PF14362.1 KEG09023.1 - 0.43 9.5 7.4 9.6 5.0 5.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF972 PF06156.8 KEG09023.1 - 0.49 10.7 8.5 10 6.5 2.2 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 KEG09023.1 - 0.68 9.5 12.8 0.78 9.2 6.1 2.4 1 1 1 2 2 2 0 IncA protein CENP-F_leu_zip PF10473.4 KEG09023.1 - 0.8 9.5 11.4 1.6 8.6 3.1 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4200 PF13863.1 KEG09023.1 - 1.1 9.2 9.5 0.37 10.7 3.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.7 KEG09023.1 - 2.7 7.7 10.9 56 3.4 7.5 2.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein COG2 PF06148.6 KEG09023.1 - 2.8 7.8 6.9 2.3 8.1 0.1 3.0 1 1 3 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Rab5-bind PF09311.6 KEG09023.1 - 3.1 7.6 12.5 0.21 11.4 0.4 3.1 2 1 0 3 3 3 0 Rabaptin-like protein ERM PF00769.14 KEG09023.1 - 3.4 7.1 15.0 5.9 6.3 6.9 2.6 2 1 0 2 2 2 0 Ezrin/radixin/moesin family Cluap1 PF10234.4 KEG09023.1 - 4.2 6.4 9.1 8.6 5.4 2.1 2.3 1 1 0 2 2 2 0 Clusterin-associated protein-1 Mod_r PF07200.8 KEG09023.1 - 5.5 6.9 11.9 0.56 10.1 0.4 2.8 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein APG6 PF04111.7 KEG09023.1 - 7.8 5.4 11.7 9.1 5.2 4.7 2.5 1 1 2 3 3 3 0 Autophagy protein Apg6 GTP_EFTU PF00009.22 KEG09024.1 - 1.6e-34 118.9 0.0 3e-34 118.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 KEG09024.1 - 6.5e-17 61.3 0.0 5.9e-16 58.2 0.0 2.4 1 1 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 KEG09024.1 - 0.00012 22.0 0.3 0.055 13.5 0.4 2.7 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Zn-ribbon_8 PF09723.5 KEG09024.1 - 0.00035 20.4 1.1 0.00085 19.2 0.7 1.7 1 0 0 1 1 1 1 Zinc ribbon domain MMR_HSR1 PF01926.18 KEG09024.1 - 0.0011 18.8 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EMA PF02488.10 KEG09024.1 - 0.2 11.0 0.3 0.38 10.2 0.0 1.5 2 0 0 2 2 2 0 Merozoite Antigen zf-C4_Topoisom PF01396.14 KEG09024.1 - 1.2 8.6 4.0 0.35 10.3 0.2 2.0 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger GTP_EFTU PF00009.22 KEG09026.1 - 1.3e-33 116.0 0.0 1.3e-33 116.0 0.0 2.3 2 1 0 2 2 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KEG09026.1 - 1.7e-14 53.6 0.1 5.2e-14 52.0 0.1 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 KEG09026.1 - 5.3e-12 45.6 0.0 1.1e-06 28.6 0.0 3.6 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KEG09026.1 - 8.4e-07 28.9 0.1 2.7e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KEG09026.1 - 0.00055 19.5 0.0 0.0016 17.9 0.0 1.8 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU_D4 PF14578.1 KEG09026.1 - 0.00072 19.1 0.0 0.0019 17.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 KEG09026.1 - 0.002 18.6 0.0 0.018 15.4 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 KEG09026.1 - 0.01 15.9 0.0 0.28 11.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KEG09026.1 - 0.018 15.0 0.0 0.018 15.0 0.0 2.7 3 1 0 3 3 3 0 AAA ATPase domain Ras PF00071.17 KEG09026.1 - 0.018 14.4 0.0 0.13 11.6 0.0 2.6 2 1 0 2 2 2 0 Ras family Reo_P9 PF06043.6 KEG09026.1 - 0.03 13.3 0.1 0.06 12.4 0.0 1.4 1 0 0 1 1 1 0 Reovirus P9-like family Nop14 PF04147.7 KEG09026.1 - 0.19 9.6 38.8 0.35 8.7 26.9 1.3 1 0 0 1 1 1 0 Nop14-like family AAA_23 PF13476.1 KEG09026.1 - 0.9 9.8 0.0 0.9 9.8 0.0 3.2 1 1 1 2 2 1 0 AAA domain DUF2694 PF10904.3 KEG09027.1 - 0.11 12.4 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2694) VIT1 PF01988.14 KEG09028.1 - 0.046 13.2 0.3 0.075 12.5 0.2 1.4 1 0 0 1 1 1 0 VIT family DUF4520 PF15016.1 KEG09029.1 - 3.5e-27 93.7 0.1 1.6e-26 91.7 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4520) COG5 PF10392.4 KEG09030.1 - 0.051 13.5 2.2 0.089 12.7 1.5 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 HECA PF15353.1 KEG09030.1 - 0.094 12.4 2.3 4 7.1 0.1 2.4 2 0 0 2 2 2 0 Headcase protein family homologue Peptidase_M8 PF01457.11 KEG09031.1 - 6.1e-147 490.0 0.3 8.5e-147 489.6 0.2 1.0 1 0 0 1 1 1 1 Leishmanolysin Astacin PF01400.19 KEG09031.1 - 0.096 12.0 0.1 0.21 10.9 0.0 1.6 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Peptidase_M57 PF12388.3 KEG09031.1 - 0.098 11.9 0.1 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M8 PF01457.11 KEG09032.1 - 1.4e-148 495.5 0.5 1.7e-148 495.2 0.4 1.0 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M57 PF12388.3 KEG09032.1 - 0.079 12.2 0.1 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase DUF1025 PF06262.6 KEG09032.1 - 0.2 11.4 0.1 0.37 10.6 0.1 1.4 1 0 0 1 1 1 0 Possibl zinc metallo-peptidase ATP-synt_DE PF00401.15 KEG09039.1 - 0.016 15.1 10.2 0.016 15.1 7.1 2.3 2 1 1 3 3 3 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain DUF4398 PF14346.1 KEG09039.1 - 0.032 14.2 3.2 0.045 13.7 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) MFS_1 PF07690.11 KEG09040.1 - 1.4e-10 40.4 15.8 1.4e-10 40.4 10.9 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily Glyco_transf_9 PF01075.12 KEG09041.1 - 0.0015 17.8 1.7 0.003 16.8 1.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) LysM PF01476.15 KEG09043.1 - 0.022 14.6 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 LysM domain Clat_adaptor_s PF01217.15 KEG09044.1 - 2.2e-50 170.0 1.8 2.6e-50 169.8 1.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Metal_resist PF13801.1 KEG09045.1 - 0.021 14.8 0.3 0.021 14.8 0.2 5.5 3 2 3 6 6 6 0 Heavy-metal resistance Peptidase_S66 PF02016.10 KEG09045.1 - 1.1 8.1 4.1 0.42 9.5 0.5 2.0 2 0 0 2 2 2 0 LD-carboxypeptidase Clathrin PF00637.15 KEG09046.1 - 2.1e-06 27.3 0.1 8.5e-06 25.4 0.0 2.0 2 0 0 2 2 2 1 Region in Clathrin and VPS zf-RING_2 PF13639.1 KEG09046.1 - 0.0087 15.8 2.7 0.036 13.8 1.9 2.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KEG09046.1 - 0.038 14.0 2.6 0.12 12.4 1.8 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KEG09046.1 - 0.42 10.7 2.0 1.1 9.4 1.4 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_5 PF14634.1 KEG09046.1 - 0.45 10.2 6.5 0.1 12.3 1.7 2.1 2 0 0 2 2 2 0 zinc-RING finger domain Dicty_REP PF05086.7 KEG09046.1 - 2.7 5.6 1.6 5.2 4.6 1.1 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RNase_PH PF01138.16 KEG09047.1 - 2.3e-16 60.3 1.1 4.9e-16 59.2 0.0 1.9 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Amastin PF07344.6 KEG09048.1 - 4.1e-17 62.2 9.9 5.7e-17 61.7 6.9 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein SUR7 PF06687.7 KEG09048.1 - 0.44 10.0 14.3 1.4 8.4 7.1 2.0 2 0 0 2 2 2 0 SUR7/PalI family LRR_4 PF12799.2 KEG09049.1 - 1.2e-13 50.3 9.6 1.9e-05 24.1 0.9 4.8 1 1 6 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG09049.1 - 6.7e-09 35.3 10.5 0.00068 19.3 2.1 3.9 2 2 3 5 5 5 4 Leucine rich repeat LRR_9 PF14580.1 KEG09049.1 - 1.3e-06 28.1 0.0 0.00029 20.4 0.0 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.1 KEG09049.1 - 0.00098 18.9 9.2 5.5 7.3 0.1 5.4 2 2 3 5 5 5 1 Leucine Rich repeat LRR_1 PF00560.28 KEG09049.1 - 0.0023 17.7 13.1 15 6.1 0.5 6.8 5 2 1 6 6 6 1 Leucine Rich Repeat LRR_7 PF13504.1 KEG09049.1 - 0.003 17.4 13.1 57 4.5 0.0 7.4 8 0 0 8 8 8 0 Leucine rich repeat ARGLU PF15346.1 KEG09050.1 - 0.0068 16.1 10.9 0.0074 16.0 7.6 1.0 1 0 0 1 1 1 1 Arginine and glutamate-rich 1 Nucleo_P87 PF07267.6 KEG09050.1 - 0.0073 15.0 0.2 0.0074 15.0 0.1 1.0 1 0 0 1 1 1 1 Nucleopolyhedrovirus capsid protein P87 Tektin PF03148.9 KEG09050.1 - 0.035 12.6 4.9 0.067 11.7 1.3 1.9 1 1 1 2 2 2 0 Tektin family UPF0449 PF15136.1 KEG09050.1 - 0.041 14.0 4.6 0.59 10.3 0.6 2.1 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 IFT57 PF10498.4 KEG09050.1 - 0.063 12.0 1.6 0.086 11.5 1.1 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Spc7 PF08317.6 KEG09050.1 - 0.087 11.4 3.5 0.13 10.9 2.4 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.4 KEG09050.1 - 0.14 11.0 5.9 0.17 10.7 4.1 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TarH PF02203.10 KEG09050.1 - 0.21 11.4 2.5 0.2 11.4 1.3 1.3 1 1 0 1 1 1 0 Tar ligand binding domain homologue APP_amyloid PF10515.4 KEG09050.1 - 0.21 11.8 1.0 0.27 11.5 0.1 1.6 2 0 0 2 2 1 0 beta-amyloid precursor protein C-terminus BTV_NS2 PF04514.7 KEG09050.1 - 0.47 9.2 2.6 0.55 9.0 1.8 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF1319 PF07028.6 KEG09050.1 - 0.47 10.6 2.8 0.87 9.7 1.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1319) DUF3584 PF12128.3 KEG09050.1 - 0.47 7.7 8.0 0.5 7.6 5.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) APG6 PF04111.7 KEG09050.1 - 0.58 9.1 6.6 0.7 8.8 4.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4200 PF13863.1 KEG09050.1 - 0.76 9.7 8.9 2.6 8.0 1.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) HlyD PF00529.15 KEG09050.1 - 0.77 9.0 8.0 0.88 8.8 5.5 1.1 1 0 0 1 1 1 0 HlyD family secretion protein IncA PF04156.9 KEG09050.1 - 1.2 8.6 5.7 1.9 8.0 4.0 1.3 1 0 0 1 1 1 0 IncA protein Occludin_ELL PF07303.8 KEG09050.1 - 1.5 9.6 4.0 5.5 7.7 2.7 1.8 1 1 0 1 1 1 0 Occludin homology domain ERM PF00769.14 KEG09050.1 - 1.7 8.1 11.5 2.3 7.6 3.7 1.9 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Cortex-I_coil PF09304.5 KEG09050.1 - 2.4 8.2 8.8 7 6.7 6.1 1.8 1 1 0 1 1 1 0 Cortexillin I, coiled coil DUF4164 PF13747.1 KEG09050.1 - 3.3 7.9 11.1 8.6 6.5 7.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) MerR-DNA-bind PF09278.6 KEG09050.1 - 3.3 8.1 9.9 7.5 7.0 0.2 2.6 2 1 0 2 2 2 0 MerR, DNA binding TMF_DNA_bd PF12329.3 KEG09050.1 - 4.5 7.1 7.8 1.4 8.7 2.6 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding vATP-synt_E PF01991.13 KEG09052.1 - 2.8e-42 144.2 8.8 3.2e-42 144.0 6.1 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit PduL PF06130.7 KEG09052.1 - 0.9 9.4 3.2 0.51 10.1 0.4 2.0 2 1 0 2 2 2 0 Propanediol utilisation protein PduL SPT16 PF08644.6 KEG09052.1 - 1.1 9.0 7.4 0.086 12.6 1.5 1.8 2 1 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) SseC PF04888.7 KEG09052.1 - 7 5.8 6.5 14 4.9 4.3 1.7 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family zf-ribbon_3 PF13248.1 KEG09053.1 - 4.5e-05 22.5 3.5 6.7e-05 21.9 2.4 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 KEG09053.1 - 0.00018 21.2 0.4 0.00027 20.6 0.3 1.3 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.1 KEG09053.1 - 0.04 13.4 4.1 0.12 11.8 2.8 1.8 1 1 1 2 2 2 0 zinc-ribbon domain NOB1_Zn_bind PF08772.6 KEG09053.1 - 0.27 11.0 1.9 0.52 10.1 0.9 1.8 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like A2L_zn_ribbon PF08792.5 KEG09053.1 - 0.27 10.7 1.3 10 5.7 0.2 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain Racemase_4 PF13615.1 KEG09054.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative alanine racemase BPL_LplA_LipB PF03099.14 KEG09055.1 - 4.1e-10 39.7 0.0 3.4e-09 36.7 0.0 2.1 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family RNase_H PF00075.19 KEG09057.1 - 4.7e-16 59.3 0.0 1.2e-15 58.0 0.0 1.7 2 0 0 2 2 2 1 RNase H RVT_1 PF00078.22 KEG09058.1 - 8.3e-30 103.7 0.2 3.2e-16 59.3 0.0 2.1 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Hydrolase_6 PF13344.1 KEG09062.1 - 2.1e-18 66.0 0.0 3.9e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KEG09062.1 - 4.9e-15 54.9 0.0 1.3e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KEG09062.1 - 2.5e-07 31.3 0.0 0.00043 20.7 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KEG09062.1 - 1.5e-06 28.5 0.0 0.00083 19.6 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 KEG09062.1 - 0.00012 21.4 0.0 0.00026 20.3 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase PEMT PF04191.8 KEG09063.1 - 3.5e-26 91.3 4.4 3.5e-26 91.3 3.0 1.6 2 0 0 2 2 2 1 Phospholipid methyltransferase Peptidase_M1 PF01433.15 KEG09064.1 - 3.9e-18 65.7 0.0 1.5e-10 40.7 0.0 2.7 2 1 0 2 2 2 2 Peptidase family M1 Peptidase_MA_2 PF13485.1 KEG09064.1 - 0.00055 19.9 0.0 0.001 19.1 0.0 1.6 1 1 0 1 1 1 1 Peptidase MA superfamily ECH PF00378.15 KEG09065.1 - 7.1e-55 185.7 0.0 9.5e-55 185.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 KEG09065.1 - 0.0098 15.6 0.2 3.2 7.5 0.0 2.4 2 0 0 2 2 2 2 Peptidase family S49 DUF3549 PF12069.3 KEG09065.1 - 0.049 12.4 0.1 0.071 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) Peripla_BP_6 PF13458.1 KEG09067.1 - 1.1e-14 54.5 0.0 7.4e-13 48.5 0.0 2.1 2 0 0 2 2 2 2 Periplasmic binding protein Fez1 PF06818.10 KEG09068.1 - 0.56 10.2 18.8 0.099 12.6 8.4 2.4 2 1 0 2 2 2 0 Fez1 WD40 PF00400.27 KEG09070.1 - 4e-32 108.9 11.1 1.9e-05 24.3 0.1 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat NLE PF08154.7 KEG09070.1 - 4.6e-15 55.3 0.2 7.5e-15 54.6 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 KEG09070.1 - 0.045 11.8 0.1 0.6 8.1 0.0 2.5 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Guanylate_cyc PF00211.15 KEG09072.1 - 8.4e-12 44.8 0.0 1.4e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PDH PF02153.12 KEG09074.1 - 0.13 11.0 0.1 0.3 9.9 0.0 1.5 2 0 0 2 2 2 0 Prephenate dehydrogenase TPR_11 PF13414.1 KEG09075.1 - 1.1e-31 108.2 11.8 3e-15 55.6 0.9 5.6 4 2 2 6 6 6 3 TPR repeat TPR_1 PF00515.23 KEG09075.1 - 5e-23 79.6 10.4 0.00068 19.1 0.1 6.8 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.12 KEG09075.1 - 2.6e-22 76.8 16.6 0.00016 21.2 0.0 7.8 7 0 0 7 7 7 5 Tetratricopeptide repeat DnaJ PF00226.26 KEG09075.1 - 2.3e-13 49.6 0.0 7.3e-13 48.0 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain TPR_8 PF13181.1 KEG09075.1 - 1.8e-09 36.6 1.7 0.14 12.0 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 KEG09075.1 - 5.3e-07 29.3 11.3 0.0042 17.1 0.2 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEG09075.1 - 5.3e-07 30.1 30.4 0.00047 20.7 0.4 6.9 4 2 3 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 KEG09075.1 - 6.6e-07 29.4 17.8 0.019 15.5 0.1 7.1 4 2 1 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEG09075.1 - 1.6e-06 28.3 12.1 0.0055 17.0 0.3 5.3 4 1 1 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 KEG09075.1 - 1.9e-06 27.8 13.5 0.0029 17.7 2.8 3.4 4 0 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KEG09075.1 - 0.00025 20.8 18.5 0.27 11.0 0.1 6.2 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.1 KEG09075.1 - 0.00079 19.0 1.6 13 5.8 0.0 4.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 KEG09075.1 - 0.0061 16.4 21.3 0.066 13.1 0.1 6.0 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 KEG09075.1 - 0.011 16.1 6.3 3 8.5 0.1 5.2 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF3808 PF10300.4 KEG09075.1 - 0.048 12.2 2.2 1.4 7.4 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3808) XPC-binding PF09280.6 KEG09076.1 - 2e-05 23.9 0.0 0.00013 21.3 0.0 2.2 2 0 0 2 2 2 1 XPC-binding domain Jag_N PF14804.1 KEG09077.1 - 0.2 11.7 0.3 0.44 10.5 0.2 1.5 1 0 0 1 1 1 0 Jag N-terminus DUF4131 PF13567.1 KEG09077.1 - 7.2 5.9 7.9 3.1 7.1 0.7 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) E1_dh PF00676.15 KEG09078.1 - 4.4e-102 340.8 0.0 5.1e-102 340.6 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 KEG09078.1 - 0.016 14.1 0.0 0.031 13.2 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase HSP70 PF00012.15 KEG09079.1 - 7.8e-114 380.7 0.4 1.6e-113 379.7 0.0 1.7 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 KEG09079.1 - 0.0067 15.0 0.0 0.034 12.7 0.0 2.3 2 1 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 KEG09079.1 - 0.017 14.7 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Herpes_UL69 PF05459.7 KEG09079.1 - 0.072 12.2 0.1 0.13 11.3 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus transcriptional regulator family FtsA PF14450.1 KEG09079.1 - 0.14 12.0 0.3 0.95 9.3 0.0 2.5 2 1 0 2 2 2 0 Cell division protein FtsA DUF2360 PF10152.4 KEG09079.1 - 0.31 11.3 13.1 0.12 12.6 5.1 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) AAA_13 PF13166.1 KEG09080.1 - 0.0019 16.7 67.1 0.0079 14.7 17.5 4.0 1 1 2 3 3 3 3 AAA domain Reo_sigmaC PF04582.7 KEG09080.1 - 0.012 14.8 22.2 4.5 6.3 0.5 6.1 4 2 3 7 7 7 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 KEG09080.1 - 0.75 9.6 122.6 0.018 14.9 11.3 8.4 2 2 7 9 9 9 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EzrA PF06160.7 KEG09080.1 - 2.4 6.2 83.3 0.0052 15.0 3.2 4.7 2 1 1 4 4 4 0 Septation ring formation regulator, EzrA APG6 PF04111.7 KEG09080.1 - 2.7 6.9 119.9 0.069 12.1 4.1 6.5 2 1 6 8 8 8 0 Autophagy protein Apg6 Matrilin_ccoil PF10393.4 KEG09080.1 - 3.2 7.1 23.8 0.76 9.1 0.2 6.4 6 0 0 6 6 6 0 Trimeric coiled-coil oligomerisation domain of matrilin Tropomyosin_1 PF12718.2 KEG09080.1 - 3.8 7.3 125.3 0.2 11.5 16.4 6.9 3 2 3 6 6 6 0 Tropomyosin like ADIP PF11559.3 KEG09080.1 - 4 7.3 128.5 0.044 13.6 15.8 9.1 4 3 6 10 10 10 0 Afadin- and alpha -actinin-Binding Laminin_II PF06009.7 KEG09080.1 - 6.1 6.6 65.2 0.3 10.8 1.3 7.9 3 1 4 8 8 8 0 Laminin Domain II Ribosomal_L9_N PF01281.14 KEG09081.1 - 0.12 11.6 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L9, N-terminal domain CorA PF01544.13 KEG09082.1 - 7e-27 94.2 1.8 4e-24 85.1 1.3 2.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein PX PF00787.19 KEG09084.1 - 1.8e-19 69.6 0.1 9.7e-10 38.2 0.0 2.5 2 0 0 2 2 2 2 PX domain AAA_16 PF13191.1 KEG09085.1 - 1.6e-06 28.2 1.0 6.4e-05 23.0 0.5 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 KEG09085.1 - 0.00096 18.6 0.2 0.0031 17.0 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain G-alpha PF00503.15 KEG09085.1 - 0.0012 17.5 0.0 0.0019 16.9 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit FtsK_SpoIIIE PF01580.13 KEG09085.1 - 0.0052 16.2 0.0 0.0093 15.4 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family MCM PF00493.18 KEG09085.1 - 0.023 13.5 0.0 0.037 12.8 0.0 1.2 1 0 0 1 1 1 0 MCM2/3/5 family AAA_22 PF13401.1 KEG09085.1 - 0.13 12.4 0.0 0.39 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC2_membrane PF01061.19 KEG09086.1 - 1.5e-31 109.1 13.6 2.4e-31 108.5 9.4 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 KEG09086.1 - 4.3e-25 88.5 0.1 6.5e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KEG09086.1 - 1.4e-08 35.0 0.0 2.3e-06 27.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEG09086.1 - 2.3e-05 24.4 0.3 0.00021 21.3 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KEG09086.1 - 0.0007 19.7 0.1 0.0044 17.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KEG09086.1 - 0.00075 18.9 0.1 0.0017 17.8 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 KEG09086.1 - 0.0009 18.5 0.2 0.42 9.7 0.0 2.7 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 KEG09086.1 - 0.0018 17.4 0.1 0.0033 16.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 KEG09086.1 - 0.012 15.0 0.1 0.036 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KEG09086.1 - 0.025 14.4 0.0 0.062 13.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KEG09086.1 - 0.03 13.9 0.0 0.058 13.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.1 KEG09086.1 - 0.039 13.7 1.6 0.061 13.0 0.1 2.1 2 0 0 2 2 1 0 Part of AAA domain AAA_10 PF12846.2 KEG09086.1 - 0.06 12.7 0.0 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain Arch_ATPase PF01637.13 KEG09086.1 - 0.062 12.9 0.0 0.098 12.3 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase T2SE PF00437.15 KEG09086.1 - 0.067 12.0 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ArgK PF03308.11 KEG09086.1 - 0.084 11.6 0.1 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 ArgK protein AAA_17 PF13207.1 KEG09086.1 - 0.088 13.6 0.0 0.18 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KEG09086.1 - 0.088 13.1 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 KEG09086.1 - 0.2 10.3 0.0 0.29 9.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein ABC2_membrane PF01061.19 KEG09087.1 - 4.9e-06 25.8 4.7 7.6e-06 25.2 3.3 1.3 1 0 0 1 1 1 1 ABC-2 type transporter SoxE PF06525.6 KEG09087.1 - 0.098 11.9 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Sulfocyanin (SoxE) Glyco_hydro_47 PF01532.15 KEG09089.1 - 1.4e-118 396.4 0.0 1.7e-118 396.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1680 PF07944.7 KEG09089.1 - 0.11 10.7 0.0 2.7 6.1 0.0 2.2 2 0 0 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) DUF229 PF02995.12 KEG09091.1 - 2.2e-19 69.2 0.0 5.4e-19 67.9 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.18 KEG09091.1 - 0.096 11.8 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Sulfatase CH PF00307.26 KEG09092.1 - 0.0011 18.9 0.1 0.0047 16.9 0.0 2.2 1 1 0 1 1 1 1 Calponin homology (CH) domain Ammonium_transp PF00909.16 KEG09094.1 - 2.1e-12 46.2 2.5 2.3e-12 46.1 1.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family TCTP PF00838.12 KEG09095.1 - 4.2e-32 111.4 0.6 4.7e-32 111.2 0.4 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein UPF0262 PF06793.7 KEG09095.1 - 0.0013 18.4 0.2 0.0017 18.1 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0262) Mus7 PF09462.5 KEG09095.1 - 0.0043 15.9 0.2 0.0049 15.7 0.1 1.0 1 0 0 1 1 1 1 Mus7/MMS22 family AAA_15 PF13175.1 KEG09095.1 - 0.0098 14.9 0.7 0.0098 14.9 0.5 1.0 1 0 0 1 1 1 1 AAA ATPase domain Ribosomal_S20p PF01649.13 KEG09095.1 - 0.014 15.7 0.7 0.021 15.2 0.5 1.3 1 0 0 1 1 1 0 Ribosomal protein S20 DUF3140 PF11338.3 KEG09095.1 - 0.041 14.0 0.3 0.062 13.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) DUF3384 PF11864.3 KEG09095.1 - 0.055 11.9 0.1 0.062 11.7 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) RICH PF05062.7 KEG09095.1 - 0.074 13.1 0.4 0.12 12.4 0.3 1.4 1 0 0 1 1 1 0 RICH domain Cauli_DNA-bind PF03310.8 KEG09095.1 - 0.12 12.1 0.1 0.21 11.4 0.0 1.5 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein ERCC4 PF02732.10 KEG09096.1 - 1.5e-20 73.4 0.0 3.4e-20 72.2 0.0 1.7 1 0 0 1 1 1 1 ERCC4 domain SAP PF02037.22 KEG09096.1 - 4.8e-08 32.3 3.4 3.7e-07 29.4 0.1 2.5 2 0 0 2 2 2 2 SAP domain Prominin PF05478.6 KEG09097.1 - 0.038 11.5 14.5 0.014 12.9 0.8 2.2 1 1 1 2 2 2 0 Prominin GP41 PF00517.12 KEG09097.1 - 0.27 10.7 0.8 11 5.5 0.0 2.7 2 0 0 2 2 2 0 Retroviral envelope protein Corona_S2 PF01601.11 KEG09097.1 - 2.7 5.9 11.6 1.3 6.9 2.9 2.4 2 0 0 2 2 2 0 Coronavirus S2 glycoprotein Helicase_C PF00271.26 KEG09098.1 - 4.6e-16 58.4 0.0 1.1e-14 54.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEG09098.1 - 9.3e-14 51.2 0.0 2.2e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase HRDC PF00570.18 KEG09098.1 - 4.6e-08 32.6 0.0 9.3e-08 31.6 0.0 1.6 1 0 0 1 1 1 1 HRDC domain Clat_adaptor_s PF01217.15 KEG09099.1 - 1.2e-42 145.0 0.5 1.3e-42 144.8 0.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Type_III_YscG PF09477.5 KEG09099.1 - 0.1 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial type II secretion system chaperone protein (type_III_yscG) p450 PF00067.17 KEG09100.1 - 9.1e-66 222.2 0.0 1.1e-65 221.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-DHHC PF01529.15 KEG09101.1 - 7.5e-26 90.5 10.6 7.5e-26 90.5 7.3 1.7 1 1 1 2 2 2 1 DHHC palmitoyltransferase Pkinase PF00069.20 KEG09103.1 - 7e-50 169.5 0.0 1.6e-49 168.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG09103.1 - 5.4e-31 107.6 0.0 9.4e-28 96.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.17 KEG09103.1 - 0.0022 17.3 0.0 0.0043 16.4 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 KEG09103.1 - 0.0032 16.4 0.0 0.012 14.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KEG09103.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family PAM2 PF07145.10 KEG09104.1 - 0.086 12.3 0.1 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Ataxin-2 C-terminal region His_Phos_1 PF00300.17 KEG09105.1 - 1.4e-12 47.9 0.0 2.9e-12 46.9 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RRM_1 PF00076.17 KEG09106.1 - 5.1e-07 29.2 0.3 1.3e-05 24.7 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG09106.1 - 9.3e-06 25.4 0.0 1.8e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG09106.1 - 0.00065 19.6 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PAM2 PF07145.10 KEG09106.1 - 0.0032 16.8 2.2 0.027 13.9 0.0 2.6 1 1 1 2 2 2 1 Ataxin-2 C-terminal region PQQ_2 PF13360.1 KEG09107.1 - 1.1e-22 80.7 27.7 1.1e-05 25.0 0.8 9.4 8 2 1 9 9 9 5 PQQ-like domain PQQ PF01011.16 KEG09107.1 - 1.4e-08 33.8 3.2 0.11 12.0 0.0 6.3 5 0 0 5 5 5 3 PQQ enzyme repeat DUF4366 PF14283.1 KEG09107.1 - 0.11 11.8 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) CD34_antigen PF06365.7 KEG09107.1 - 0.47 10.0 0.0 0.8 9.3 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF605 PF04652.11 KEG09107.1 - 2.9 7.2 5.4 5 6.4 3.7 1.2 1 0 0 1 1 1 0 Vta1 like GHMP_kinases_C PF08544.8 KEG09108.1 - 4.5e-18 65.2 0.1 1e-17 64.0 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 KEG09108.1 - 4.4e-16 58.7 0.6 8.8e-16 57.7 0.4 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain IKKbetaNEMObind PF12179.3 KEG09108.1 - 0.12 12.2 0.2 0.21 11.4 0.2 1.4 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain PDEase_I PF00233.14 KEG09109.1 - 1.1e-12 48.2 0.0 2.1e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Filament PF00038.16 KEG09109.1 - 0.00038 20.0 3.2 0.00038 20.0 2.3 3.2 3 0 0 3 3 3 2 Intermediate filament protein ERM PF00769.14 KEG09109.1 - 0.0012 18.3 4.1 0.0012 18.3 2.8 3.5 4 0 0 4 4 4 2 Ezrin/radixin/moesin family IncA PF04156.9 KEG09109.1 - 0.78 9.2 28.7 0.033 13.7 1.4 3.8 4 0 0 4 4 4 0 IncA protein APG6 PF04111.7 KEG09109.1 - 8.2 5.3 20.8 0.89 8.5 2.6 3.1 3 0 0 3 3 3 0 Autophagy protein Apg6 Atg14 PF10186.4 KEG09109.1 - 9.3 5.0 21.8 0.97 8.3 1.8 3.6 3 1 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 ABC_membrane_2 PF06472.10 KEG09110.1 - 5.7e-64 215.9 5.0 8.4e-64 215.4 3.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KEG09110.1 - 8.4e-17 61.7 0.0 1.7e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 KEG09110.1 - 4.7e-05 22.7 0.2 0.073 12.2 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KEG09110.1 - 0.0015 18.5 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEG09110.1 - 0.0057 16.6 0.0 0.021 14.7 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.1 KEG09110.1 - 0.016 15.5 0.0 0.025 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KEG09110.1 - 0.021 14.5 0.0 0.041 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 KEG09110.1 - 0.025 14.0 0.0 0.066 12.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.10 KEG09110.1 - 0.038 12.6 0.0 0.064 11.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DUF815 PF05673.8 KEG09110.1 - 0.051 12.4 0.0 0.096 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TraG-D_C PF12696.2 KEG09110.1 - 0.068 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG AAA_10 PF12846.2 KEG09110.1 - 0.11 11.8 0.1 1.3 8.3 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain AAA_22 PF13401.1 KEG09110.1 - 0.12 12.5 0.0 0.34 11.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 KEG09110.1 - 0.13 12.4 0.0 0.44 10.7 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TRM13 PF05206.9 KEG09112.1 - 3.5e-64 216.5 0.0 3.2e-62 210.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase TRM13 zf-U11-48K PF05253.7 KEG09112.1 - 3.7e-10 39.2 2.2 6.8e-10 38.4 1.6 1.5 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.1 KEG09112.1 - 4.8e-05 23.0 2.5 0.025 14.2 0.6 2.5 2 0 0 2 2 2 2 Methyltransferase domain Pkinase PF00069.20 KEG09113.1 - 9.8e-57 192.0 0.0 1.5e-56 191.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG09113.1 - 4.7e-34 117.6 0.0 8.1e-34 116.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG09113.1 - 2.2e-09 36.7 0.0 1.6e-08 33.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KEG09113.1 - 0.00022 21.0 1.0 0.16 11.6 0.1 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family DUF4423 PF14394.1 KEG09113.1 - 0.014 14.9 0.1 0.044 13.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) zf-C2H2_jaz PF12171.3 KEG09113.1 - 0.022 14.8 2.7 0.05 13.7 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Seadorna_VP7 PF07387.6 KEG09113.1 - 0.26 10.0 0.0 0.48 9.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 ZZ PF00569.12 KEG09113.1 - 0.29 10.7 10.6 0.031 13.8 4.0 2.0 2 0 0 2 2 2 0 Zinc finger, ZZ type C1_3 PF07649.7 KEG09113.1 - 0.45 10.6 12.0 0.058 13.4 5.0 2.1 2 0 0 2 2 2 0 C1-like domain FYVE_2 PF02318.11 KEG09113.1 - 1.1 9.2 5.5 3 7.7 3.8 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger C1_2 PF03107.11 KEG09113.1 - 5.9 7.1 13.2 0.15 12.2 4.3 2.1 2 0 0 2 2 1 0 C1 domain Elf1 PF05129.8 KEG09113.1 - 6.1 6.6 9.2 1.8 8.3 2.9 2.3 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Microtub_assoc PF07989.6 KEG09115.1 - 0.025 14.3 0.3 0.025 14.3 0.2 8.1 8 1 2 10 10 10 0 Microtubule associated zf-C2H2_jaz PF12171.3 KEG09121.1 - 0.00019 21.4 0.0 1.4 9.1 0.0 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 KEG09121.1 - 0.0016 18.6 7.0 0.12 12.7 0.2 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-met PF12874.2 KEG09121.1 - 0.0018 18.3 0.4 3.5 7.9 0.0 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KEG09121.1 - 0.011 15.7 1.0 0.64 10.1 0.0 2.5 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 KEG09121.1 - 0.016 15.4 10.2 0.047 14.0 0.2 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger zf-Di19 PF05605.7 KEG09121.1 - 0.025 14.6 7.9 0.49 10.5 0.4 3.5 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.10 KEG09121.1 - 0.03 14.0 1.4 0.64 9.8 0.0 3.3 3 0 0 3 3 3 0 BED zinc finger zf-H2C2_2 PF13465.1 KEG09121.1 - 8.1 6.9 15.9 13 6.3 0.3 4.3 3 1 0 3 3 3 0 Zinc-finger double domain Zn_Tnp_IS1595 PF12760.2 KEG09122.1 - 0.026 14.3 0.5 0.056 13.2 0.4 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain UPF0547 PF10571.4 KEG09122.1 - 0.059 13.0 0.2 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 Zn_Tnp_IS1595 PF12760.2 KEG09123.1 - 0.026 14.3 0.5 0.056 13.2 0.4 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain UPF0547 PF10571.4 KEG09123.1 - 0.059 13.0 0.2 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 Pro_isomerase PF00160.16 KEG09124.1 - 2.8e-47 160.8 0.1 3.2e-47 160.6 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TMF_DNA_bd PF12329.3 KEG09125.1 - 0.059 13.1 0.1 0.25 11.1 0.0 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding OapA PF04225.7 KEG09125.1 - 0.11 12.3 0.0 0.48 10.3 0.0 1.9 1 1 1 2 2 2 0 Opacity-associated protein A LysM-like domain RVT_1 PF00078.22 KEG09129.1 - 0.003 16.9 0.0 0.0037 16.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Adipokin_hormo PF06377.6 KEG09132.1 - 0.008 16.2 0.0 0.037 14.1 0.0 2.1 1 0 0 1 1 1 1 Adipokinetic hormone DUF4129 PF13559.1 KEG09133.1 - 0.065 13.2 0.4 0.065 13.2 0.2 3.3 4 1 0 4 4 4 0 Domain of unknown function (DUF4129) LRAT PF04970.8 KEG09133.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Lecithin retinol acyltransferase SNF2_N PF00176.18 KEG09134.1 - 1e-65 221.5 0.4 1.6e-65 220.8 0.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEG09134.1 - 1.5e-13 50.3 0.0 4.1e-13 48.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEG09134.1 - 2.8e-07 30.2 0.0 7.5e-07 28.7 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 KEG09134.1 - 0.0016 17.3 0.0 0.025 13.3 0.0 2.3 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AAA_11 PF13086.1 KEG09134.1 - 0.0065 16.0 1.0 0.14 11.6 0.7 3.2 2 1 0 2 2 2 1 AAA domain AChE_tetra PF08674.5 KEG09134.1 - 0.035 13.6 0.2 0.035 13.6 0.1 2.2 3 0 0 3 3 3 0 Acetylcholinesterase tetramerisation domain OGG_N PF07934.7 KEG09135.1 - 3.6e-24 84.9 0.0 6.7e-24 84.1 0.0 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 KEG09135.1 - 1.4e-10 41.3 0.0 4.3e-10 39.8 0.0 1.8 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KEG09135.1 - 0.00015 21.2 0.0 0.00049 19.6 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 KEG09135.1 - 0.14 12.3 0.1 3.5 7.8 0.1 2.4 1 1 0 1 1 1 0 Helix-hairpin-helix domain HEAT_2 PF13646.1 KEG09136.1 - 0.084 13.1 0.1 0.084 13.1 0.1 3.3 3 1 1 4 4 4 0 HEAT repeats Pkinase PF00069.20 KEG09137.1 - 1.1e-45 155.7 0.0 4e-33 114.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEG09137.1 - 2e-25 89.3 0.0 1.8e-20 73.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase DSPc PF00782.15 KEG09137.1 - 8.9e-25 86.8 0.0 1.6e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain LRR_8 PF13855.1 KEG09137.1 - 4.7e-14 51.8 17.1 9.5e-08 31.6 1.3 3.5 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 KEG09137.1 - 1.1e-10 40.8 9.4 4.8e-07 29.2 2.4 3.7 1 1 3 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEG09137.1 - 1.7e-07 30.3 7.4 1.9 8.8 0.2 5.8 5 0 0 5 5 5 3 Leucine Rich Repeat Kinase-like PF14531.1 KEG09137.1 - 9.5e-07 28.0 0.0 0.0019 17.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like LRR_7 PF13504.1 KEG09137.1 - 0.0048 16.8 2.5 32 5.3 0.1 4.6 4 0 0 4 4 4 0 Leucine rich repeat Y_phosphatase PF00102.22 KEG09137.1 - 0.017 14.5 0.1 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Kdo PF06293.9 KEG09137.1 - 0.18 10.8 0.2 5.5 6.0 0.1 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family ERM PF00769.14 KEG09138.1 - 0.0016 18.0 0.4 0.002 17.7 0.3 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Rab5-bind PF09311.6 KEG09138.1 - 0.01 15.7 2.5 0.015 15.1 1.7 1.2 1 0 0 1 1 1 1 Rabaptin-like protein Pol_alpha_B_N PF08418.5 KEG09138.1 - 0.063 12.7 0.0 0.1 12.1 0.0 1.4 1 1 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Myosin_tail_1 PF01576.14 KEG09138.1 - 0.22 9.1 6.3 0.27 8.8 4.4 1.1 1 0 0 1 1 1 0 Myosin tail DUF4647 PF15504.1 KEG09139.1 - 0.039 12.8 0.4 0.053 12.3 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) DUF2217 PF10265.4 KEG09139.1 - 1.3 7.7 7.7 0.054 12.2 0.5 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) F-protein PF00469.15 KEG09139.1 - 1.6 8.0 4.5 2.9 7.2 3.1 1.3 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef SR-25 PF10500.4 KEG09139.1 - 2.9 7.3 15.9 0.057 12.8 2.3 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein GDI PF00996.13 KEG09140.1 - 6.5e-31 107.0 0.0 9.1e-20 70.3 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor Methyltransf_16 PF10294.4 KEG09140.1 - 1.7e-13 50.3 0.0 2.6e-07 30.2 0.0 2.4 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 KEG09140.1 - 0.0018 18.8 0.2 0.011 16.2 0.1 2.5 2 0 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 KEG09140.1 - 0.0025 16.8 0.0 0.0049 15.8 0.0 1.4 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family MTS PF05175.9 KEG09140.1 - 0.079 12.3 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain DPM2 PF07297.7 KEG09141.1 - 7.6e-14 51.7 1.0 1e-13 51.3 0.7 1.2 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF2189 PF09955.4 KEG09141.1 - 0.024 14.5 1.6 0.032 14.1 1.1 1.1 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2189) 7tm_7 PF08395.7 KEG09141.1 - 0.051 12.5 0.1 0.059 12.3 0.1 1.0 1 0 0 1 1 1 0 7tm Chemosensory receptor Pex16 PF08610.5 KEG09142.1 - 2.9e-32 111.9 0.0 1e-28 100.3 0.0 2.1 2 0 0 2 2 2 2 Peroxisomal membrane protein (Pex16) WW PF00397.21 KEG09144.1 - 4.2e-13 48.8 2.6 8.9e-07 28.6 0.3 2.4 2 0 0 2 2 2 2 WW domain Coatomer_WDAD PF04053.9 KEG09147.1 - 1.1e-140 469.4 0.0 2.9e-140 467.9 0.0 1.7 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 KEG09147.1 - 8.7e-41 136.3 0.2 6.7e-10 38.4 0.0 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat zf-RanBP PF00641.13 KEG09148.1 - 2.8e-27 93.5 47.7 5.8e-08 31.7 0.6 6.4 6 0 0 6 6 6 6 Zn-finger in Ran binding protein and others DZR PF12773.2 KEG09148.1 - 0.00074 19.2 41.2 0.029 14.2 4.7 4.8 2 2 3 5 5 5 5 Double zinc ribbon PhnA_Zn_Ribbon PF08274.7 KEG09148.1 - 4.7 7.0 13.0 1.3 8.8 0.4 4.3 4 1 0 4 4 4 0 PhnA Zinc-Ribbon EF-hand_7 PF13499.1 KEG09149.1 - 9.7e-05 22.4 0.1 0.0052 16.9 0.1 3.1 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 KEG09149.1 - 0.00054 19.6 0.1 0.0075 16.0 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 KEG09149.1 - 0.00097 18.3 0.0 0.0031 16.7 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.27 KEG09149.1 - 0.0058 15.8 0.0 0.069 12.4 0.0 2.7 2 0 0 2 2 2 1 EF hand TT_ORF2 PF02957.10 KEG09150.1 - 6.3 7.5 10.2 3.3 8.4 6.0 1.3 1 1 0 1 1 1 0 TT viral ORF2 Herpes_UL6 PF01763.11 KEG09151.1 - 0.0023 16.1 0.7 0.0023 16.1 0.5 1.8 2 0 0 2 2 2 1 Herpesvirus UL6 like ApbA_C PF08546.6 KEG09151.1 - 0.27 11.2 2.2 0.19 11.6 0.3 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal Atg14 PF10186.4 KEG09151.1 - 7.9 5.3 21.7 1.9 7.3 3.4 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 A_deaminase PF00962.17 KEG09152.1 - 8e-84 281.3 0.0 5.3e-61 206.3 0.0 2.6 2 1 0 2 2 2 2 Adenosine/AMP deaminase PIG-S PF10510.4 KEG09153.1 - 0.0087 14.7 0.0 0.024 13.3 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein DUF462 PF04315.7 KEG09157.1 - 0.0094 15.3 0.2 0.012 15.0 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF462 NOB1_Zn_bind PF08772.6 KEG09159.1 - 8.8e-27 92.7 0.2 1.7e-26 91.8 0.1 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like AF1Q PF15017.1 KEG09159.1 - 0.36 10.7 24.3 0.54 10.1 12.9 2.9 2 1 0 2 2 2 0 Drug resistance and apoptosis regulator Hexapep PF00132.19 KEG09161.1 - 8e-09 34.6 14.2 0.0013 18.1 0.0 4.7 3 1 0 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Sipho_Gp157 PF05565.6 KEG09162.1 - 0.00043 19.9 12.6 0.091 12.3 1.3 3.7 1 1 2 3 3 3 2 Siphovirus Gp157 Reo_sigmaC PF04582.7 KEG09162.1 - 0.021 13.9 15.8 0.22 10.6 1.6 3.8 1 1 3 4 4 4 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 KEG09162.1 - 0.097 12.4 16.7 3.1 7.6 2.3 5.0 2 1 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus WXG100 PF06013.7 KEG09162.1 - 0.16 12.0 35.8 0.19 11.7 2.1 7.2 5 3 1 7 7 7 0 Proteins of 100 residues with WXG Tropomyosin_1 PF12718.2 KEG09162.1 - 0.21 11.4 41.9 0.049 13.4 4.6 4.3 2 1 2 4 4 4 0 Tropomyosin like DUF489 PF04356.7 KEG09162.1 - 0.24 10.9 14.7 0.38 10.3 0.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF489) MitMem_reg PF13012.1 KEG09162.1 - 0.26 11.3 13.9 0.67 10.0 2.0 3.6 1 1 2 3 3 3 0 Maintenance of mitochondrial structure and function HTH_20 PF12840.2 KEG09162.1 - 0.33 10.8 0.1 0.33 10.8 0.1 3.7 4 0 0 4 4 4 0 Helix-turn-helix domain Sec3_C_2 PF15278.1 KEG09162.1 - 0.36 10.9 4.0 2.7 8.1 0.0 3.7 2 1 1 3 3 3 0 Sec3 exocyst complex subunit NPV_P10 PF05531.7 KEG09162.1 - 1.2 9.3 21.4 6.4 7.1 0.2 6.1 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Baculo_p24 PF05073.7 KEG09162.1 - 1.4 8.4 16.7 0.96 8.9 2.9 3.4 2 1 1 3 3 3 0 Baculovirus P24 capsid protein DUF1664 PF07889.7 KEG09162.1 - 1.4 8.7 24.9 0.25 11.1 0.7 4.4 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) DUF948 PF06103.6 KEG09162.1 - 2.8 7.8 12.5 37 4.2 0.1 4.7 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF3939 PF13075.1 KEG09162.1 - 2.9 7.6 6.9 0.41 10.3 0.2 2.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3939) Apolipoprotein PF01442.13 KEG09162.1 - 3.3 7.1 51.2 1.6 8.1 23.9 3.6 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain MRP-L46 PF11788.3 KEG09162.1 - 4.8 7.8 18.4 0.8 10.3 9.0 2.4 2 1 0 2 2 2 0 39S mitochondrial ribosomal protein L46 MxiH PF09392.5 KEG09162.1 - 5.2 7.6 14.9 21 5.7 1.6 4.3 1 1 1 2 2 2 0 Type III secretion needle MxiH like DUF3708 PF12501.3 KEG09162.1 - 9 6.1 22.5 0.25 11.1 0.5 4.1 3 1 1 4 4 4 0 Phosphate ATP-binding cassette transporter Mucin PF01456.12 KEG09164.1 - 3.9e-07 29.9 16.0 5.1e-05 23.0 3.9 4.0 3 2 0 3 3 3 2 Mucin-like glycoprotein DUF2570 PF10828.3 KEG09164.1 - 0.063 12.8 0.2 0.063 12.8 0.1 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF2570) FtsA PF14450.1 KEG09164.1 - 0.19 11.5 8.6 9.3 6.1 5.9 2.6 1 1 0 1 1 1 0 Cell division protein FtsA PP2C_C PF07830.8 KEG09164.1 - 0.22 11.6 1.9 0.47 10.5 0.1 2.5 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain Myc_target_1 PF15179.1 KEG09166.1 - 0.1 12.1 0.5 0.12 11.9 0.3 1.1 1 0 0 1 1 1 0 Myc target protein 1 DUF3533 PF12051.3 KEG09167.1 - 1.5 7.5 3.5 2.6 6.6 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Hanta_G1 PF01567.11 KEG09167.1 - 2.4 6.3 4.1 3.9 5.6 2.8 1.2 1 0 0 1 1 1 0 Hantavirus glycoprotein G1 DUF3614 PF12267.3 KEG09167.1 - 2.6 8.3 6.8 1.4 9.1 2.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3614) DUF2422 PF10337.4 KEG09167.1 - 8.3 5.0 12.6 1.8 7.2 5.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2422) Mucin PF01456.12 KEG09168.1 - 0.00018 21.3 0.5 0.00018 21.3 0.3 4.5 4 1 0 4 4 4 2 Mucin-like glycoprotein Toxin_56 PF15534.1 KEG09168.1 - 0.1 13.0 0.1 0.1 13.0 0.0 2.7 3 0 0 3 3 3 0 Putative toxin 56 IGFBP PF00219.13 KEG09170.1 - 0.33 11.5 7.1 5 7.7 0.2 2.4 2 0 0 2 2 2 0 Insulin-like growth factor binding protein Mucin PF01456.12 KEG09171.1 - 1.1e-07 31.6 26.6 0.0049 16.6 0.2 3.3 2 1 0 2 2 2 2 Mucin-like glycoprotein GAS PF13851.1 KEG09171.1 - 0.0095 15.1 0.9 0.0095 15.1 0.6 3.3 3 1 1 4 4 4 1 Growth-arrest specific micro-tubule binding IFP_35_N PF07334.8 KEG09171.1 - 0.024 14.5 0.7 0.089 12.7 0.3 2.1 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Shisa PF13908.1 KEG09171.1 - 0.066 13.3 0.2 0.066 13.3 0.2 2.9 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator Kinesin PF00225.18 KEG09172.1 - 1.5e-105 352.6 0.2 1.5e-105 352.6 0.1 1.7 2 0 0 2 2 2 1 Kinesin motor domain VHS PF00790.14 KEG09172.1 - 2.2e-08 33.8 1.8 5.8e-08 32.4 0.1 2.7 3 0 0 3 3 3 1 VHS domain Tup_N PF08581.5 KEG09172.1 - 0.31 11.2 14.8 1.9 8.7 3.3 3.9 3 0 0 3 3 3 0 Tup N-terminal EAP30 PF04157.11 KEG09172.1 - 2.4 7.2 13.5 47 3.0 9.4 2.7 1 1 0 1 1 1 0 EAP30/Vps36 family DUF87 PF01935.12 KEG09172.1 - 6.2 6.5 17.7 6.3 6.5 0.1 3.8 3 1 1 4 4 4 0 Domain of unknown function DUF87 UVR PF02151.14 KEG09173.1 - 3.5e-06 26.3 13.3 0.00077 18.8 2.6 2.5 2 0 0 2 2 2 2 UvrB/uvrC motif zf-Di19 PF05605.7 KEG09173.1 - 2.7e-05 24.1 12.5 0.00082 19.4 2.2 3.4 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding CLASP_N PF12348.3 KEG09173.1 - 0.00029 20.2 0.0 0.00054 19.3 0.0 1.4 1 0 0 1 1 1 1 CLASP N terminal HEAT PF02985.17 KEG09173.1 - 0.013 15.4 4.6 3.1 8.1 0.0 4.6 5 0 0 5 5 5 0 HEAT repeat Tropomyosin_1 PF12718.2 KEG09173.1 - 0.019 14.8 3.0 0.037 13.8 2.1 1.4 1 0 0 1 1 1 0 Tropomyosin like zinc-ribbons_6 PF07191.7 KEG09173.1 - 5.1 6.9 14.2 0.021 14.6 1.8 2.6 2 1 1 3 3 3 0 zinc-ribbons GN3L_Grn1 PF08701.6 KEG09174.1 - 1.2e-05 25.1 13.2 1.2e-05 25.1 9.1 2.4 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase Complex1_LYR PF05347.10 KEG09175.1 - 3.4e-07 29.9 0.2 2.1e-06 27.4 0.0 2.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KEG09175.1 - 9e-05 22.5 1.5 0.00029 20.9 0.0 2.7 2 1 0 2 2 2 1 Complex1_LYR-like PapD_N PF00345.15 KEG09176.1 - 0.0046 16.7 0.0 0.073 12.8 0.0 3.1 3 0 0 3 3 3 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain Suf PF05843.9 KEG09176.1 - 0.072 12.8 0.0 0.072 12.8 0.0 2.7 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) EF-hand_6 PF13405.1 KEG09177.1 - 0.0002 20.9 0.0 0.00059 19.5 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 KEG09177.1 - 0.00062 19.8 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KEG09177.1 - 0.0019 17.3 0.0 0.0045 16.1 0.0 1.6 1 0 0 1 1 1 1 EF hand PBP1_TM PF14812.1 KEG09177.1 - 0.43 10.9 7.3 0.98 9.7 5.0 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SSI PF00720.12 KEG09178.1 - 0.016 15.1 0.6 2.9 7.8 0.1 2.8 2 0 0 2 2 2 0 Subtilisin inhibitor-like RHD3 PF05879.7 KEG09179.1 - 9.3e-103 344.5 0.6 4.1e-92 309.3 0.0 2.9 2 1 0 3 3 3 2 Root hair defective 3 GTP-binding protein (RHD3) AAA_28 PF13521.1 KEG09179.1 - 5.8e-05 23.1 0.8 0.00015 21.7 0.1 2.1 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 KEG09179.1 - 0.00015 21.6 0.0 0.00028 20.7 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 KEG09179.1 - 0.0053 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KEG09179.1 - 0.0077 16.7 0.0 0.023 15.2 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 KEG09179.1 - 0.076 13.3 0.0 0.34 11.2 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Septin PF00735.13 KEG09179.1 - 0.13 11.2 0.0 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 Septin Mago-bind PF09282.5 KEG09179.1 - 1.8 8.1 3.6 0.81 9.3 0.3 2.1 2 0 0 2 2 2 0 Mago binding Ninjurin PF04923.7 KEG09181.1 - 0.05 13.3 6.4 2.3 7.9 2.5 2.7 2 0 0 2 2 2 0 Ninjurin HILPDA PF15220.1 KEG09181.1 - 0.13 12.2 0.0 0.13 12.2 0.0 2.4 3 0 0 3 3 3 0 Hypoxia-inducible lipid droplet-associated MitMem_reg PF13012.1 KEG09182.1 - 2.3e-20 72.8 0.1 2.3e-20 72.8 0.1 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 KEG09182.1 - 1.6e-17 63.2 0.0 1.7e-16 59.9 0.0 2.1 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Mt_ATP-synt_B PF05405.9 KEG09182.1 - 0.029 13.8 0.5 0.094 12.1 0.1 1.8 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF1664 PF07889.7 KEG09182.1 - 0.075 12.8 3.3 0.38 10.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TAN PF11640.3 KEG09182.1 - 0.079 12.6 0.2 0.079 12.6 0.2 2.0 2 1 0 2 2 2 0 Telomere-length maintenance and DNA damage repair RNase_H2-Ydr279 PF09468.5 KEG09182.1 - 0.16 11.1 0.3 0.22 10.6 0.2 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) MscS_TM PF12794.2 KEG09182.1 - 0.2 10.2 1.1 0.28 9.7 0.7 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 SlyX PF04102.7 KEG09182.1 - 0.65 10.4 3.7 3.3 8.1 0.1 2.6 2 1 1 3 3 3 0 SlyX DUF3938 PF13074.1 KEG09183.1 - 0.38 10.6 6.2 0.072 12.9 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) Sec5 PF15469.1 KEG09184.1 - 0.031 13.9 4.4 0.048 13.4 2.5 1.6 1 1 0 1 1 1 0 Exocyst complex component Sec5 YkuI_C PF10388.4 KEG09184.1 - 5.3 6.6 7.5 22 4.6 0.1 2.4 2 0 0 2 2 2 0 EAL-domain associated signalling protein domain GBP_PSP PF02425.10 KEG09187.1 - 0.1 12.1 0.9 0.25 10.8 0.7 1.6 1 0 0 1 1 1 0 Paralytic/GBP/PSP peptide Aldo_ket_red PF00248.16 KEG09188.1 - 2.3e-64 216.9 0.0 2.6e-64 216.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HAD_2 PF13419.1 KEG09188.1 - 0.056 13.6 0.0 0.17 12.1 0.0 1.7 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF673 PF05054.7 KEG09188.1 - 0.1 11.1 0.0 0.14 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF673) DNA_pol_A PF00476.15 KEG09189.1 - 6.4e-29 100.7 0.0 1.6e-28 99.3 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase family A RNase_T PF00929.19 KEG09189.1 - 2.2e-18 67.0 0.0 1.3e-17 64.5 0.0 2.3 3 0 0 3 3 3 1 Exonuclease Motile_Sperm PF00635.21 KEG09190.1 - 5.8e-09 35.5 0.2 0.19 11.3 0.2 7.0 8 0 0 8 8 8 3 MSP (Major sperm protein) domain MYCBPAP PF14646.1 KEG09190.1 - 0.73 8.4 0.0 1.5 7.4 0.0 1.4 1 0 0 1 1 1 0 MYCBP-associated protein family DUF3122 PF11320.3 KEG09191.1 - 0.035 14.0 0.5 6.2 6.7 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3122) NYD-SP28_assoc PF14775.1 KEG09193.1 - 0.0055 16.3 0.8 0.0091 15.6 0.5 1.3 1 0 0 1 1 1 1 Sperm tail C-terminal domain HALZ PF02183.13 KEG09193.1 - 0.027 14.1 0.1 0.041 13.5 0.1 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_2 PF07716.10 KEG09193.1 - 0.055 13.3 1.5 0.095 12.5 1.1 1.3 1 0 0 1 1 1 0 Basic region leucine zipper Grp1_Fun34_YaaH PF01184.14 KEG09195.1 - 0.043 13.1 0.1 0.049 12.9 0.0 1.1 1 0 0 1 1 1 0 GPR1/FUN34/yaaH family TPR_11 PF13414.1 KEG09196.1 - 3.1e-23 81.1 10.0 2.3e-05 23.9 0.1 6.0 4 1 1 5 5 5 5 TPR repeat TPR_2 PF07719.12 KEG09196.1 - 1.5e-11 43.2 14.2 0.009 15.8 0.0 9.3 9 1 1 10 10 9 2 Tetratricopeptide repeat TPR_1 PF00515.23 KEG09196.1 - 3.3e-08 32.7 11.9 0.01 15.4 0.0 8.5 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEG09196.1 - 9.2e-08 32.3 3.5 0.033 14.5 0.2 5.9 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 KEG09196.1 - 1.8e-07 30.8 18.2 0.02 14.7 0.1 6.1 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 KEG09196.1 - 4e-07 29.3 2.7 0.042 13.6 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEG09196.1 - 7e-07 29.0 12.7 0.027 14.3 0.0 5.8 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 KEG09196.1 - 1.2e-05 25.7 8.7 0.89 10.3 0.0 6.0 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEG09196.1 - 2.2e-05 24.6 14.9 3 8.7 0.1 8.0 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.1 KEG09196.1 - 2.4e-05 23.7 0.2 0.017 14.9 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 KEG09196.1 - 3.2e-05 23.9 12.9 4.5 7.4 0.3 7.3 4 1 3 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.3 KEG09196.1 - 0.00044 19.1 0.1 0.037 12.7 0.1 2.3 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 TPR_17 PF13431.1 KEG09196.1 - 0.0011 18.9 1.3 4.8 7.6 0.0 4.5 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_20 PF14561.1 KEG09196.1 - 0.0031 17.5 0.6 1.3 9.2 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 KEG09196.1 - 0.048 13.5 1.2 0.91 9.5 0.1 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat XRN_N PF03159.13 KEG09197.1 - 2.7e-83 279.0 0.0 5.5e-83 277.9 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus CGGC PF08821.6 KEG09198.1 - 0.097 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 CGGC domain MORN PF02493.15 KEG09199.1 - 7e-61 198.4 111.1 9.9e-08 31.2 0.7 20.1 21 1 0 21 21 21 16 MORN repeat DUF3048 PF11258.3 KEG09199.1 - 7 5.6 7.5 8.8 5.3 0.1 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF3048) HTH_38 PF13936.1 KEG09200.1 - 0.00063 19.2 0.0 0.0024 17.3 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain KorB PF08535.5 KEG09200.1 - 0.0058 16.7 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 KorB domain HTH_23 PF13384.1 KEG09200.1 - 0.022 14.3 0.2 0.11 12.1 0.0 2.2 2 1 0 2 2 2 0 Homeodomain-like domain PAT1 PF09770.4 KEG09201.1 - 2.1 6.5 10.6 2.8 6.0 7.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 KEG09201.1 - 6.5 6.5 12.4 11 5.7 8.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sirohm_synth_C PF14823.1 KEG09201.1 - 6.5 6.1 6.1 1.7 7.9 0.4 2.4 2 0 0 2 2 2 0 Sirohaem biosynthesis protein C-terminal DUF2382 PF09557.5 KEG09202.1 - 0.0096 15.8 0.1 0.024 14.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2382) 2OG-FeII_Oxy_2 PF13532.1 KEG09203.1 - 8.1e-10 38.8 0.0 6e-09 36.0 0.0 2.2 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UPF0029 PF01205.14 KEG09204.1 - 1.3e-28 98.8 0.0 2.6e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 KEG09204.1 - 5.1e-07 29.5 0.0 1.3e-06 28.2 0.0 1.7 1 1 0 1 1 1 1 RWD domain Galactosyl_T PF01762.16 KEG09206.1 - 2.6e-05 23.9 0.0 0.0031 17.1 0.0 3.1 3 1 0 3 3 3 2 Galactosyltransferase Galactosyl_T PF01762.16 KEG09207.1 - 1.1e-08 34.8 0.3 0.0046 16.5 0.0 3.4 3 1 0 4 4 4 3 Galactosyltransferase Galactosyl_T PF01762.16 KEG09208.1 - 4e-05 23.3 0.0 0.012 15.2 0.0 3.3 3 1 0 3 3 3 1 Galactosyltransferase Peptidase_C2 PF00648.16 KEG09209.1 - 1.7e-32 112.6 0.0 2.4e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 KEG09209.1 - 7.2e-25 86.9 0.0 1.3e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Fe-ADH PF00465.14 KEG09212.1 - 8.7e-119 396.3 3.9 9.9e-119 396.2 2.7 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 KEG09212.1 - 6.8e-20 71.4 2.2 3.6e-09 36.2 0.0 2.1 1 1 1 2 2 2 2 Iron-containing alcohol dehydrogenase Lamprin PF06403.6 KEG09212.1 - 0.03 14.0 1.3 0.076 12.7 0.3 2.1 2 0 0 2 2 2 0 Lamprin GTP_EFTU PF00009.22 KEG09213.1 - 3.3e-57 192.9 0.1 5.7e-57 192.1 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KEG09213.1 - 1.1e-19 70.3 0.2 2.5e-18 66.0 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KEG09213.1 - 1.4e-07 31.4 0.4 3.5e-07 30.2 0.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KEG09213.1 - 0.00029 20.7 0.0 0.00067 19.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 KEG09213.1 - 0.0035 16.9 0.1 0.0095 15.5 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 KEG09213.1 - 0.036 14.5 0.0 0.09 13.2 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Tctex-1 PF03645.8 KEG09214.1 - 4.9e-25 87.3 0.1 6.5e-25 86.9 0.1 1.2 1 0 0 1 1 1 1 Tctex-1 family Thiol-ester_cl PF10569.4 KEG09215.1 - 4.8 6.4 6.8 1.9 7.8 0.3 2.5 2 0 0 2 2 2 0 Alpha-macro-globulin thiol-ester bond-forming region Methyltransf_11 PF08241.7 KEG09216.1 - 2.2e-19 69.7 0.0 6e-10 39.4 0.0 2.8 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.1 KEG09216.1 - 5.3e-15 55.3 0.0 8.1e-08 31.9 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 KEG09216.1 - 7.7e-13 48.4 0.0 1.6e-07 31.2 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 KEG09216.1 - 6.7e-12 45.6 0.3 3.5e-05 24.0 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 KEG09216.1 - 1.2e-09 38.6 0.0 0.00014 22.4 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 KEG09216.1 - 2.3e-09 37.6 0.0 0.0016 18.8 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain CMAS PF02353.15 KEG09216.1 - 3.1e-09 36.3 0.2 7.8e-06 25.1 0.0 2.2 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase DOT1 PF08123.8 KEG09216.1 - 6.3e-08 32.1 0.0 0.00054 19.3 0.0 2.2 2 0 0 2 2 2 2 Histone methylation protein DOT1 Ubie_methyltran PF01209.13 KEG09216.1 - 6.1e-06 25.5 0.0 0.013 14.6 0.0 2.2 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family PCMT PF01135.14 KEG09216.1 - 7.8e-06 25.5 0.0 0.00058 19.4 0.0 2.3 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 KEG09216.1 - 1e-05 24.9 0.0 0.046 13.1 0.0 2.2 2 0 0 2 2 2 2 Methionine biosynthesis protein MetW Methyltransf_26 PF13659.1 KEG09216.1 - 2e-05 24.5 0.0 0.12 12.4 0.0 3.2 2 2 0 2 2 2 2 Methyltransferase domain Methyltransf_32 PF13679.1 KEG09216.1 - 7.9e-05 22.3 0.1 0.25 11.0 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain SyrA PF11089.3 KEG09216.1 - 0.023 14.5 0.9 0.54 10.0 0.1 2.3 2 0 0 2 2 2 0 Exopolysaccharide production repressor DUF1496 PF07383.7 KEG09216.1 - 0.091 12.0 0.1 2.1 7.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1496) UQ_con PF00179.21 KEG09217.1 - 1.7e-40 137.6 0.0 1.9e-40 137.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TMEM154 PF15102.1 KEG09218.1 - 0.049 13.3 0.2 0.13 11.9 0.1 1.7 1 0 0 1 1 1 0 TMEM154 protein family SIT PF15330.1 KEG09218.1 - 0.33 11.1 0.6 0.71 10.0 0.4 1.5 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT S1FA PF04689.8 KEG09218.1 - 0.74 9.7 2.1 1.5 8.7 1.5 1.4 1 0 0 1 1 1 0 DNA binding protein S1FA DUF3021 PF11457.3 KEG09218.1 - 0.84 9.5 2.7 1.5 8.6 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) PspB PF06667.7 KEG09218.1 - 0.87 9.5 1.2 2.1 8.3 0.7 1.7 2 0 0 2 2 2 0 Phage shock protein B Adeno_E3_CR2 PF02439.10 KEG09218.1 - 7.3 6.2 9.8 0.24 10.9 2.4 1.8 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Amastin PF07344.6 KEG09219.1 - 7.7e-17 61.3 10.6 1.1e-16 60.8 7.3 1.2 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF3810 PF12725.2 KEG09219.1 - 0.054 12.3 2.9 0.083 11.7 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) PrgI PF12666.2 KEG09219.1 - 0.63 10.2 11.0 1 9.5 2.4 3.0 2 1 1 3 3 3 0 PrgI family protein Claudin_2 PF13903.1 KEG09219.1 - 1.8 8.2 14.7 0.54 9.9 8.1 1.6 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction RRM_1 PF00076.17 KEG09220.1 - 2.3e-19 68.8 0.1 3.3e-19 68.2 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG09220.1 - 5.6e-15 55.0 0.0 7.6e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG09220.1 - 4.9e-08 32.7 0.0 6.5e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEG09221.1 - 1.1e-17 63.3 0.0 2.8e-17 62.0 0.1 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG09221.1 - 3e-12 46.3 0.0 4.7e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG09221.1 - 5e-07 29.4 0.0 7.3e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEG09222.1 - 5.4e-17 61.1 0.0 1.2e-16 60.0 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG09222.1 - 2e-11 43.6 0.0 3.3e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG09222.1 - 0.00015 21.4 0.0 0.00022 20.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WW PF00397.21 KEG09223.1 - 0.056 13.3 0.1 0.056 13.3 0.1 1.9 2 0 0 2 2 2 0 WW domain Zn-ribbon_8 PF09723.5 KEG09226.1 - 1 9.3 4.5 1.8 8.5 0.1 2.7 3 0 0 3 3 3 0 Zinc ribbon domain NR_Repeat PF14046.1 KEG09227.1 - 0.54 10.0 2.8 0.27 11.0 0.6 1.5 2 0 0 2 2 2 0 Nuclear receptor repeat LRR_4 PF12799.2 KEG09228.1 - 8.9e-28 95.4 0.0 0.00021 20.8 0.0 8.5 2 2 8 10 10 10 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG09228.1 - 1.3e-22 79.3 2.4 0.00016 21.3 0.0 5.8 5 1 0 5 5 5 5 Leucine rich repeat LRR_6 PF13516.1 KEG09228.1 - 1.8e-15 55.1 7.7 0.069 13.2 0.0 9.7 9 3 1 10 10 10 4 Leucine Rich repeat LRR_1 PF00560.28 KEG09228.1 - 1.6e-13 48.6 14.4 14 6.1 0.0 12.6 13 1 1 14 14 14 3 Leucine Rich Repeat LRR_7 PF13504.1 KEG09228.1 - 2.3e-05 23.8 17.3 7.6 7.2 0.0 10.7 11 1 1 12 12 12 2 Leucine rich repeat LRR_4 PF12799.2 KEG09229.1 - 1.2e-13 50.3 6.8 0.0016 18.0 0.0 5.7 1 1 6 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG09229.1 - 3.7e-11 42.6 9.6 0.00022 20.9 0.0 4.2 1 1 4 5 5 5 5 Leucine rich repeat LRR_6 PF13516.1 KEG09229.1 - 6e-09 35.0 12.6 0.021 14.8 0.0 7.6 7 2 1 8 8 8 2 Leucine Rich repeat LRR_1 PF00560.28 KEG09229.1 - 0.00018 21.1 13.1 21 5.6 0.0 7.4 6 2 0 6 6 6 1 Leucine Rich Repeat LRR_7 PF13504.1 KEG09229.1 - 0.59 10.5 15.7 1.8e+02 3.0 0.0 7.7 5 3 3 8 8 8 0 Leucine rich repeat DUF740 PF05340.7 KEG09231.1 - 1.4 7.2 6.1 1.5 7.0 4.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Mucin PF01456.12 KEG09232.1 - 2.6e-08 33.7 22.9 0.00013 21.7 11.3 2.8 2 1 0 2 2 2 2 Mucin-like glycoprotein RNA_pol_Rpa2_4 PF06883.7 KEG09232.1 - 0.24 11.3 0.8 4.4 7.3 0.1 2.2 2 0 0 2 2 2 0 RNA polymerase I, Rpa2 specific domain Totivirus_coat PF05518.6 KEG09232.1 - 7.4 4.2 7.5 9.2 3.9 5.2 1.3 1 0 0 1 1 1 0 Totivirus coat protein Peptidase_M8 PF01457.11 KEG09233.1 - 2.6e-11 42.5 0.5 3.3e-11 42.2 0.4 1.1 1 0 0 1 1 1 1 Leishmanolysin Mucin PF01456.12 KEG09233.1 - 3.4e-06 26.8 1.1 4.3e-06 26.5 0.7 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein Peptidase_M8 PF01457.11 KEG09234.1 - 8.4e-24 83.7 0.1 1.1e-23 83.3 0.1 1.1 1 0 0 1 1 1 1 Leishmanolysin DUF4131 PF13567.1 KEG09234.1 - 0.029 13.7 5.2 0.42 9.9 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) HTH_29 PF13551.1 KEG09234.1 - 0.062 13.4 1.6 0.097 12.8 0.5 1.8 2 0 0 2 2 2 0 Winged helix-turn helix PPR PF01535.15 KEG09235.1 - 0.0034 17.2 0.0 0.53 10.3 0.0 2.2 2 0 0 2 2 2 2 PPR repeat PPR_3 PF13812.1 KEG09235.1 - 0.0083 16.3 0.1 4.2 7.8 0.1 2.3 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 KEG09235.1 - 0.012 15.5 0.0 0.21 11.5 0.0 2.0 1 1 1 2 2 2 0 PPR repeat family TPR_12 PF13424.1 KEG09235.1 - 0.09 12.7 0.3 0.35 10.8 0.1 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3250 PF11618.3 KEG09237.1 - 9.8e-25 86.8 3.0 1.9e-24 85.9 0.1 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3250) Phostensin_N PF13916.1 KEG09237.1 - 0.27 11.2 10.3 0.019 14.9 2.3 2.8 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal RICTOR_M PF14666.1 KEG09239.1 - 1.2e-51 174.8 0.3 3.9e-51 173.2 0.2 1.9 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_N PF14664.1 KEG09239.1 - 1.9e-14 53.0 4.9 1.6e-10 40.1 0.2 2.8 3 0 0 3 3 3 2 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.1 KEG09239.1 - 2.1e-10 40.5 1.1 3.6e-08 33.3 0.3 3.0 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 KEG09239.1 - 3.6e-09 36.4 5.5 1.8e-08 34.2 0.5 3.7 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT PF02985.17 KEG09239.1 - 0.059 13.4 0.6 0.71 10.1 0.0 3.1 2 0 0 2 2 2 0 HEAT repeat RasGEF PF00617.14 KEG09240.1 - 4.7e-27 94.9 0.0 6.6e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KEG09240.1 - 1.4e-15 57.2 0.1 3e-15 56.1 0.1 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif ABC_membrane PF00664.18 KEG09241.1 - 3.5e-46 157.8 2.5 5e-46 157.3 1.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KEG09241.1 - 8.6e-31 107.0 0.0 1.5e-30 106.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KEG09241.1 - 0.00011 22.2 0.0 0.36 10.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KEG09241.1 - 0.0003 20.1 0.0 0.29 10.3 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KEG09241.1 - 0.0012 18.9 0.7 0.045 13.9 0.5 2.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KEG09241.1 - 0.0018 18.4 0.1 0.019 15.1 0.1 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.4 KEG09241.1 - 0.0024 16.5 0.0 0.0046 15.6 0.0 1.3 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_16 PF13191.1 KEG09241.1 - 0.0064 16.4 0.6 0.059 13.3 0.2 2.3 3 0 0 3 3 2 1 AAA ATPase domain AAA_25 PF13481.1 KEG09241.1 - 0.0074 15.6 0.0 0.13 11.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KEG09241.1 - 0.019 15.7 0.0 0.038 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 KEG09241.1 - 0.033 14.0 0.0 0.075 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_29 PF13555.1 KEG09241.1 - 0.042 13.3 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 KEG09241.1 - 0.068 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 KEG09241.1 - 0.072 12.1 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_10 PF12846.2 KEG09241.1 - 0.084 12.2 0.6 0.46 9.8 0.2 2.1 2 0 0 2 2 2 0 AAA-like domain RRM_1 PF00076.17 KEG09242.1 - 6.5e-18 64.1 0.0 1e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG09242.1 - 7.3e-11 41.9 0.0 1.2e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG09242.1 - 9.1e-11 41.4 0.1 1.4e-10 40.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RR_TM4-6 PF06459.7 KEG09242.1 - 0.6 9.9 5.7 0.73 9.6 4.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tim54 PF11711.3 KEG09242.1 - 1.1 7.8 5.6 1.2 7.5 3.9 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4557 PF15101.1 KEG09242.1 - 8.4 6.1 9.0 13 5.5 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) RRM_1 PF00076.17 KEG09244.1 - 2.9e-21 74.8 0.0 4.5e-21 74.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG09244.1 - 1.7e-14 53.5 0.0 3e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG09244.1 - 2.8e-11 43.0 0.0 4.6e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAT1 PF09770.4 KEG09244.1 - 2.1 6.5 41.8 0.14 10.3 22.2 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 CorA PF01544.13 KEG09249.1 - 1.7e-15 56.8 2.7 1.9e-08 33.6 0.7 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Peptidase_M20 PF01546.23 KEG09250.1 - 3.1e-34 118.1 0.1 3.9e-34 117.8 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KEG09250.1 - 8.3e-21 73.8 0.0 1.4e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M42 PF05343.9 KEG09250.1 - 9.7e-05 21.2 0.1 0.018 13.8 0.0 2.6 3 0 0 3 3 3 2 M42 glutamyl aminopeptidase Tctex-1 PF03645.8 KEG09251.1 - 3.3e-24 84.6 0.1 3.8e-24 84.4 0.1 1.0 1 0 0 1 1 1 1 Tctex-1 family TALPID3 PF15324.1 KEG09251.1 - 0.056 10.7 0.0 0.067 10.5 0.0 1.0 1 0 0 1 1 1 0 Hedgehog signalling target TFIIE-A_C-term PF11521.3 KEG09251.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha PG_binding_2 PF08823.6 KEG09251.1 - 0.13 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative peptidoglycan binding domain Ribosomal_S11 PF00411.14 KEG09252.1 - 1.1e-41 141.3 0.3 1.4e-41 141.1 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 LSM PF01423.17 KEG09253.1 - 0.051 13.1 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 LSM domain Vps39_2 PF10367.4 KEG09255.1 - 1.6e-23 82.9 1.6 3e-23 82.0 1.1 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.15 KEG09255.1 - 0.0067 16.0 0.0 0.021 14.4 0.0 1.8 1 0 0 1 1 1 1 Region in Clathrin and VPS Cyclin_N PF00134.18 KEG09256.1 - 0.31 10.5 1.3 1 8.9 0.2 2.0 2 0 0 2 2 2 0 Cyclin, N-terminal domain DUF2360 PF10152.4 KEG09258.1 - 8.3 6.6 7.5 12 6.1 5.2 1.4 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Malic_M PF03949.10 KEG09260.1 - 1e-78 264.4 0.2 1.4e-78 264.0 0.1 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KEG09260.1 - 3.4e-63 212.4 0.0 5.1e-63 211.9 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain SNF2_N PF00176.18 KEG09261.1 - 4.1e-61 206.3 0.0 6.8e-61 205.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEG09261.1 - 1.9e-15 56.4 0.0 5.3e-15 55.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEG09261.1 - 1.2e-11 44.3 0.0 2.3e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KEG09261.1 - 8.7e-05 22.4 0.0 0.0002 21.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TFIIA PF03153.8 KEG09261.1 - 0.21 11.4 12.7 0.02 14.8 4.1 2.5 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit RRM_1 PF00076.17 KEG09262.1 - 6.9e-07 28.8 0.1 1.3e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG09262.1 - 3e-05 23.9 0.0 4.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2984 PF11203.3 KEG09262.1 - 0.0067 16.5 0.1 0.27 11.3 0.1 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2984) RRM_5 PF13893.1 KEG09262.1 - 0.012 15.4 0.0 0.051 13.4 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DDE_Tnp_ISAZ013 PF07592.6 KEG09262.1 - 0.11 11.2 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain TMF_DNA_bd PF12329.3 KEG09263.1 - 0.00089 19.0 2.3 0.00089 19.0 1.6 2.4 2 1 0 2 2 2 1 TATA element modulatory factor 1 DNA binding PLRV_ORF5 PF01690.12 KEG09263.1 - 0.041 13.0 1.6 0.054 12.6 1.1 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein CbbQ_C PF08406.5 KEG09263.1 - 0.091 12.7 0.9 0.21 11.5 0.1 2.0 2 0 0 2 2 2 0 CbbQ/NirQ/NorQ C-terminal CENP-F_leu_zip PF10473.4 KEG09263.1 - 0.81 9.5 12.9 0.11 12.2 2.1 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Macoilin PF09726.4 KEG09263.1 - 0.9 7.7 13.5 1.9 6.6 9.4 1.4 1 1 0 1 1 1 0 Transmembrane protein Not3 PF04065.10 KEG09263.1 - 2 7.6 10.3 3.7 6.7 1.0 2.2 1 1 1 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component IncA PF04156.9 KEG09263.1 - 2 7.9 9.7 3.4 7.2 6.7 1.3 1 0 0 1 1 1 0 IncA protein DUF904 PF06005.7 KEG09263.1 - 4.6 7.6 10.0 18 5.6 6.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF972 PF06156.8 KEG09263.1 - 6.5 7.1 7.5 86 3.5 5.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Apelin PF15360.1 KEG09263.1 - 7.8 6.7 7.8 16 5.8 0.5 3.7 3 1 1 4 4 4 0 APJ endogenous ligand APG6 PF04111.7 KEG09263.1 - 8.2 5.3 10.0 19 4.1 6.9 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 ATP-synt_10 PF05176.9 KEG09266.1 - 5.7e-06 25.7 0.0 1.4e-05 24.5 0.0 1.6 2 0 0 2 2 2 1 ATP10 protein AAA_12 PF13087.1 KEG09267.1 - 7.3e-61 205.0 0.0 1.4e-60 204.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain UPF1_Zn_bind PF09416.5 KEG09267.1 - 5.6e-60 201.3 4.5 1.1e-59 200.4 3.1 1.5 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) AAA_11 PF13086.1 KEG09267.1 - 2.7e-55 187.5 0.3 4.4e-55 186.8 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEG09267.1 - 8.7e-16 57.4 0.1 4.3e-15 55.2 0.1 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KEG09267.1 - 1.5e-12 47.5 0.0 2.8e-11 43.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.16 KEG09267.1 - 3.3e-06 26.6 0.0 0.02 14.1 0.0 2.3 1 1 1 2 2 2 2 UvrD/REP helicase N-terminal domain PhoH PF02562.11 KEG09267.1 - 0.00012 21.3 0.0 0.00026 20.2 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein Helicase_RecD PF05127.9 KEG09267.1 - 0.00028 20.5 0.0 0.00053 19.6 0.0 1.6 1 1 0 1 1 1 1 Helicase ResIII PF04851.10 KEG09267.1 - 0.00087 19.1 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 KEG09267.1 - 0.0095 14.9 1.5 0.024 13.6 0.0 2.3 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 KEG09267.1 - 0.018 14.5 0.2 0.037 13.5 0.2 1.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA PF00004.24 KEG09267.1 - 0.021 15.0 0.0 0.042 14.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 KEG09267.1 - 0.031 13.7 0.1 1.9 7.9 0.0 3.0 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 KEG09267.1 - 0.031 14.4 0.1 0.29 11.2 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KEG09267.1 - 0.055 13.7 0.1 0.22 11.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.9 KEG09267.1 - 0.057 12.3 0.0 3.4 6.5 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase AAA_16 PF13191.1 KEG09267.1 - 0.095 12.6 0.0 0.46 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain DBR1 PF05011.8 KEG09268.1 - 3.1e-08 33.6 0.0 6.8e-08 32.5 0.0 1.5 1 1 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos_2 PF12850.2 KEG09268.1 - 0.0045 16.8 0.0 0.0093 15.8 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KEG09268.1 - 0.012 15.0 0.9 2.5 7.4 0.0 2.2 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase PK PF00224.16 KEG09269.1 - 0.068 11.7 0.1 0.095 11.2 0.1 1.1 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain CD52 PF15116.1 KEG09269.1 - 0.087 12.6 2.1 0.15 11.8 0.1 2.5 2 0 0 2 2 2 0 CAMPATH-1 antigen ApoLp-III PF07464.6 KEG09271.1 - 0.093 12.7 0.0 0.5 10.3 0.0 1.9 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Glyco_trans_1_2 PF13524.1 KEG09271.1 - 0.44 10.8 0.0 0.44 10.8 0.0 2.6 2 1 0 2 2 2 0 Glycosyl transferases group 1 Frataxin_Cyay PF01491.11 KEG09272.1 - 1.9e-26 91.9 0.0 2.4e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain FIST PF08495.5 KEG09272.1 - 0.0047 16.1 0.1 0.0069 15.5 0.0 1.2 1 0 0 1 1 1 1 FIST N domain Pox_MCEL PF03291.11 KEG09276.1 - 1.5e-12 47.0 0.0 2.5e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.1 KEG09276.1 - 0.00034 20.9 0.0 0.0022 18.3 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEG09276.1 - 0.0013 19.1 0.0 0.0038 17.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEG09276.1 - 0.0025 17.5 0.0 0.022 14.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain mRNA_cap_enzyme PF01331.14 KEG09276.1 - 0.039 13.6 0.0 0.09 12.4 0.0 1.5 1 0 0 1 1 1 0 mRNA capping enzyme, catalytic domain OSCP PF00213.13 KEG09276.1 - 0.17 11.7 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit TPR_11 PF13414.1 KEG09277.1 - 1.3e-26 92.0 34.4 1e-11 44.2 0.5 4.8 2 1 4 6 6 6 6 TPR repeat TPR_1 PF00515.23 KEG09277.1 - 1.3e-20 72.0 19.5 2.1e-06 27.1 1.6 6.7 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 KEG09277.1 - 2.4e-16 58.2 21.9 0.00028 20.5 1.5 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 KEG09277.1 - 1.8e-11 44.4 18.2 4.8e-07 30.2 1.0 4.9 3 3 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 KEG09277.1 - 4.7e-11 42.4 14.4 9.7e-05 22.2 1.6 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 KEG09277.1 - 6.3e-11 41.5 9.6 0.001 19.1 0.9 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEG09277.1 - 2.4e-10 40.5 11.7 4.2e-05 23.8 0.5 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 KEG09277.1 - 8.1e-10 37.7 18.9 0.0015 18.1 0.1 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEG09277.1 - 8.3e-09 34.5 9.1 0.0024 17.5 0.1 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEG09277.1 - 1.2e-08 34.7 15.4 0.0024 18.3 1.1 5.6 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_6 PF13174.1 KEG09277.1 - 3.5e-08 33.3 6.7 0.0058 17.0 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 KEG09277.1 - 6e-05 23.0 6.9 0.0031 17.6 1.5 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 KEG09277.1 - 0.00066 19.7 3.0 0.74 9.9 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF1395 PF07160.7 KEG09277.1 - 0.0034 16.9 0.2 0.014 14.9 0.4 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1395) TPR_9 PF13371.1 KEG09277.1 - 0.048 13.5 10.5 1.2 9.0 0.3 3.7 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 KEG09277.1 - 0.065 13.1 7.0 3.2 7.8 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 KEG09277.1 - 3.2 8.4 5.2 3.2 8.4 0.1 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat Pkinase PF00069.20 KEG09279.1 - 1.2e-40 139.3 0.0 1.7e-40 138.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG09279.1 - 4.5e-21 75.0 0.0 2.8e-20 72.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 KEG09279.1 - 0.058 12.9 0.2 0.093 12.2 0.2 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 KEG09279.1 - 0.094 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AA_permease_2 PF13520.1 KEG09280.1 - 1.1e-23 83.4 36.0 1.5e-23 83.0 25.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KEG09280.1 - 2.1e-10 39.5 34.3 3.9e-10 38.6 23.8 1.4 1 1 0 1 1 1 1 Amino acid permease PepSY_TM_1 PF13172.1 KEG09280.1 - 2 8.2 8.6 0.78 9.5 0.4 4.0 3 1 0 3 3 3 0 PepSY-associated TM helix Ribonuclease_3 PF00636.21 KEG09281.1 - 0.031 14.7 0.0 0.15 12.5 0.0 2.1 1 1 0 1 1 1 0 Ribonuclease III domain SUV3_C PF12513.3 KEG09281.1 - 0.075 12.4 0.0 0.19 11.1 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal AATF-Che1 PF13339.1 KEG09283.1 - 3.1e-14 53.2 0.3 3.1e-14 53.2 0.2 4.5 4 3 1 5 5 5 1 Apoptosis antagonizing transcription factor EcKinase PF02958.15 KEG09283.1 - 0.028 13.5 0.7 0.046 12.8 0.5 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase V_ATPase_I PF01496.14 KEG09283.1 - 0.056 11.3 3.4 1.6 6.4 0.2 2.1 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family Nop53 PF07767.6 KEG09283.1 - 0.63 8.9 18.4 0.25 10.3 8.3 2.6 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Nop14 PF04147.7 KEG09283.1 - 9.3 4.0 28.0 2.1 6.1 16.8 1.8 2 0 0 2 2 2 0 Nop14-like family Tho2 PF11262.3 KEG09284.1 - 0.0063 15.6 0.0 0.037 13.0 0.0 1.9 2 0 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 DUF4047 PF13256.1 KEG09284.1 - 0.036 14.0 0.3 0.23 11.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) Proteasome PF00227.21 KEG09286.1 - 1.9e-58 196.8 0.0 2.5e-58 196.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KEG09286.1 - 8.7e-15 53.7 0.2 1.4e-14 53.0 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature AAA_25 PF13481.1 KEG09287.1 - 4.8e-17 62.0 0.5 9.3e-17 61.0 0.4 1.4 1 0 0 1 1 1 1 AAA domain Rad51 PF08423.6 KEG09287.1 - 8.1e-15 54.4 0.0 1.5e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Rad51 KaiC PF06745.8 KEG09287.1 - 3.2e-07 29.6 0.0 5.6e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.1 KEG09287.1 - 6e-05 23.2 0.2 0.00017 21.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KEG09287.1 - 0.0001 22.0 0.1 0.0002 21.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain RecA PF00154.16 KEG09287.1 - 0.0008 18.5 0.1 0.0047 16.0 0.0 2.0 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_19 PF13245.1 KEG09287.1 - 0.0019 17.8 0.6 0.0056 16.3 0.4 1.9 1 0 0 1 1 1 1 Part of AAA domain DnaB_C PF03796.10 KEG09287.1 - 0.0074 15.2 0.1 0.083 11.7 0.0 2.1 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_28 PF13521.1 KEG09287.1 - 0.029 14.3 0.4 0.064 13.2 0.3 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 KEG09287.1 - 0.16 10.9 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Pterin_4a PF01329.14 KEG09288.1 - 1.7e-28 98.2 0.9 1.9e-28 98.0 0.6 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase PA PF02225.17 KEG09289.1 - 3.4e-07 29.8 2.5 4.1e-06 26.4 1.7 2.0 1 1 0 1 1 1 1 PA domain Pyrophosphatase PF00719.14 KEG09290.1 - 5.9e-51 172.0 0.0 1e-50 171.2 0.0 1.4 1 0 0 1 1 1 1 Inorganic pyrophosphatase EF-hand_7 PF13499.1 KEG09290.1 - 0.0081 16.2 0.3 0.034 14.2 0.3 2.0 2 1 0 2 2 2 1 EF-hand domain pair LRR_6 PF13516.1 KEG09292.1 - 8e-07 28.4 0.1 0.001 18.9 0.0 4.2 4 0 0 4 4 4 1 Leucine Rich repeat LRR_4 PF12799.2 KEG09292.1 - 0.0051 16.4 0.0 0.021 14.4 0.0 2.1 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEG09292.1 - 0.0084 16.0 0.0 0.66 10.2 0.0 3.6 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_8 PF13855.1 KEG09292.1 - 0.064 13.0 0.3 0.53 10.0 0.0 2.5 1 1 1 2 2 2 0 Leucine rich repeat DEAD PF00270.24 KEG09293.1 - 3.7e-24 85.1 0.0 7.9e-24 84.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEG09293.1 - 1.4e-05 24.8 0.0 4.7e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEG09293.1 - 8.5e-05 22.4 0.0 0.00017 21.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.11 KEG09293.1 - 0.013 14.6 0.0 0.027 13.6 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein VIT1 PF01988.14 KEG09295.1 - 3.5e-61 206.3 4.8 4.3e-61 206.1 3.3 1.1 1 0 0 1 1 1 1 VIT family DUF1678 PF07913.6 KEG09296.1 - 0.0081 15.7 0.2 0.024 14.1 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1678) SET PF00856.23 KEG09296.1 - 0.02 15.2 0.0 0.045 14.0 0.0 1.6 2 0 0 2 2 2 0 SET domain Selenoprotein_S PF06936.6 KEG09297.1 - 0.085 12.3 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) Adeno_PV PF03910.8 KEG09297.1 - 0.83 8.6 3.6 0.94 8.4 0.8 1.8 1 1 1 2 2 2 0 Adenovirus minor core protein PV XPG_I PF00867.13 KEG09298.1 - 3.5e-30 103.9 0.0 6.4e-30 103.0 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KEG09298.1 - 1.7e-25 89.1 0.0 3.3e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.15 KEG09298.1 - 4.8e-06 26.7 0.1 2.9e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Sigma70_r1_1 PF03979.9 KEG09298.1 - 0.0054 16.6 0.5 0.012 15.4 0.3 1.6 1 0 0 1 1 1 1 Sigma-70 factor, region 1.1 5_3_exonuc_N PF02739.11 KEG09298.1 - 0.033 13.5 0.0 0.11 11.8 0.0 1.7 1 1 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain PDE6_gamma PF04868.7 KEG09300.1 - 9.4 6.1 7.7 4.5 7.1 0.2 3.4 3 0 0 3 3 3 0 Retinal cGMP phosphodiesterase, gamma subunit PP-binding PF00550.20 KEG09301.1 - 1.8e-10 40.9 0.3 2.6e-10 40.4 0.2 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site DIM1 PF02966.11 KEG09301.1 - 0.037 13.5 0.1 0.049 13.1 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 PP-binding_2 PF14573.1 KEG09301.1 - 0.13 12.3 0.3 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Acyl-carrier FAD-oxidase_C PF02913.14 KEG09302.1 - 2.2e-44 151.6 0.5 3.3e-44 151.0 0.3 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KEG09302.1 - 6.3e-37 126.1 1.5 2.4e-36 124.2 0.7 2.1 2 0 0 2 2 2 1 FAD binding domain Ish1 PF10281.4 KEG09303.1 - 0.035 14.1 0.3 0.11 12.6 0.2 1.9 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein SAP30_Sin3_bdg PF13867.1 KEG09303.1 - 0.037 13.9 0.1 0.082 12.7 0.1 1.6 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 TTL PF03133.10 KEG09304.1 - 4.4e-48 163.7 0.0 7.1e-22 77.6 0.0 3.1 3 0 0 3 3 3 3 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 KEG09304.1 - 0.024 13.4 0.0 0.91 8.2 0.0 2.4 2 1 0 2 2 2 0 YheC/D like ATP-grasp ATP-grasp_3 PF02655.9 KEG09304.1 - 0.057 13.2 0.0 2.2 8.1 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain DIOX_N PF14226.1 KEG09305.1 - 1.4e-27 96.4 0.0 1.7e-27 96.2 0.0 1.0 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KEG09306.1 - 7.4e-24 83.9 0.0 1.1e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RIO1 PF01163.17 KEG09307.1 - 4.2e-66 221.8 0.2 1.1e-65 220.4 0.0 1.9 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 KEG09307.1 - 0.021 14.5 0.1 0.15 11.7 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Sigma70_ner PF04546.8 KEG09307.1 - 1.2 8.6 10.7 0.47 10.0 5.4 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region PIP5K PF01504.13 KEG09308.1 - 1.3e-41 142.3 0.0 1.6e-41 142.1 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase PIP5K PF01504.13 KEG09309.1 - 4.2e-16 58.8 0.0 4.6e-16 58.6 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase WD40 PF00400.27 KEG09311.1 - 8.8e-19 66.6 10.4 6.1e-06 25.9 0.1 8.0 7 1 0 7 7 7 5 WD domain, G-beta repeat EF-hand_1 PF00036.27 KEG09311.1 - 0.0011 18.1 0.0 0.0024 17.0 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 KEG09311.1 - 0.0014 17.9 0.0 0.0032 16.7 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 KEG09311.1 - 0.0023 18.0 0.0 0.0061 16.6 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KEG09311.1 - 0.0043 16.8 0.0 0.026 14.3 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 KEG09311.1 - 0.03 13.9 0.0 0.092 12.3 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair Metallophos PF00149.23 KEG09313.1 - 7.3e-07 28.7 1.6 2.4e-06 27.0 1.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Shisa PF13908.1 KEG09314.1 - 0.00044 20.4 0.0 0.00044 20.4 0.0 1.9 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator TMEM51 PF15345.1 KEG09314.1 - 0.0024 17.6 0.2 0.0033 17.1 0.1 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 7tm_1 PF00001.16 KEG09314.1 - 0.0066 15.6 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Herpes_glycop PF01528.11 KEG09314.1 - 0.023 13.3 0.0 0.03 13.0 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus glycoprotein M OAD_gamma PF04277.8 KEG09314.1 - 0.032 14.6 0.0 0.078 13.3 0.0 1.7 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain IncA PF04156.9 KEG09314.1 - 0.038 13.6 3.0 0.068 12.7 0.0 2.1 2 0 0 2 2 2 0 IncA protein Gemini_mov PF01708.11 KEG09314.1 - 0.054 13.0 0.2 0.17 11.4 0.2 1.9 1 1 0 1 1 1 0 Geminivirus putative movement protein MtlR PF05068.7 KEG09314.1 - 0.09 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Mannitol repressor Prominin PF05478.6 KEG09314.1 - 0.22 9.0 1.7 0.29 8.6 1.2 1.1 1 0 0 1 1 1 0 Prominin RCR PF12273.3 KEG09314.1 - 0.24 11.9 5.4 2.3 8.7 3.7 2.1 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Prenyltrans PF00432.16 KEG09315.1 - 2.3e-24 84.6 20.4 7.3e-06 25.4 0.4 6.5 7 0 0 7 7 7 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KEG09315.1 - 5.2e-15 55.8 2.6 4e-10 40.0 0.0 4.2 3 1 1 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 KEG09315.1 - 0.0029 17.6 0.1 0.99 9.4 0.0 2.9 1 1 1 2 2 2 2 Prenyltransferase-like COG7 PF10191.4 KEG09316.1 - 1.5e-24 85.9 14.9 1.8e-19 69.1 8.7 2.2 2 0 0 2 2 2 2 Golgi complex component 7 (COG7) DUF2450 PF10475.4 KEG09316.1 - 0.00093 18.1 6.5 0.0019 17.1 4.5 1.5 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) PilJ PF13675.1 KEG09316.1 - 0.11 12.7 18.9 7.9 6.8 0.3 6.6 4 2 3 7 7 7 0 Type IV pili methyl-accepting chemotaxis transducer N-term Vps51 PF08700.6 KEG09316.1 - 0.72 9.7 5.6 13 5.7 0.2 3.6 1 1 2 3 3 3 0 Vps51/Vps67 Baculo_PEP_C PF04513.7 KEG09316.1 - 2.9 7.7 14.4 3.4 7.5 0.8 4.2 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus V_ATPase_I PF01496.14 KEG09316.1 - 3.4 5.4 7.3 5.4 4.7 5.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YlbD_coat PF14071.1 KEG09316.1 - 4 7.5 8.3 4.7 7.2 1.3 2.8 1 1 1 2 2 2 0 Putative coat protein Sad1_UNC PF07738.8 KEG09321.1 - 4.8e-20 71.7 0.0 7.3e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Snapin_Pallidin PF14712.1 KEG09321.1 - 0.015 15.5 3.1 0.027 14.7 2.2 1.3 1 0 0 1 1 1 0 Snapin/Pallidin WEMBL PF05701.6 KEG09321.1 - 0.015 13.7 0.7 0.021 13.3 0.5 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Macoilin PF09726.4 KEG09321.1 - 0.055 11.7 8.7 0.08 11.2 6.0 1.2 1 0 0 1 1 1 0 Transmembrane protein Laminin_II PF06009.7 KEG09321.1 - 0.079 12.7 0.3 0.14 11.8 0.2 1.3 1 0 0 1 1 1 0 Laminin Domain II ATG16 PF08614.6 KEG09321.1 - 3.2 7.5 9.0 0.067 13.0 0.4 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) RabGAP-TBC PF00566.13 KEG09322.1 - 1.1e-09 38.0 0.1 1.7e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Rhodanese PF00581.15 KEG09322.1 - 0.046 14.0 0.0 0.099 12.9 0.0 1.5 1 0 0 1 1 1 0 Rhodanese-like domain Ku_PK_bind PF08785.6 KEG09323.1 - 0.068 13.0 0.0 0.077 12.8 0.0 1.1 1 0 0 1 1 1 0 Ku C terminal domain like Brix PF04427.13 KEG09324.1 - 3e-44 150.9 0.2 3.8e-44 150.6 0.2 1.1 1 0 0 1 1 1 1 Brix domain Clathrin PF00637.15 KEG09325.1 - 1.5e-11 44.0 0.5 4.4e-11 42.5 0.3 1.8 1 0 0 1 1 1 1 Region in Clathrin and VPS zf-RING_2 PF13639.1 KEG09325.1 - 0.00081 19.1 1.9 0.0021 17.8 1.3 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KEG09325.1 - 0.0025 17.7 1.8 0.011 15.7 1.3 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) LysM PF01476.15 KEG09325.1 - 0.016 15.1 0.3 0.038 13.8 0.2 1.6 1 0 0 1 1 1 0 LysM domain Vps39_2 PF10367.4 KEG09325.1 - 0.021 15.0 0.0 0.063 13.4 0.0 1.9 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 Pox_A_type_inc PF04508.7 KEG09326.1 - 0.43 10.4 11.8 0.38 10.6 0.1 4.6 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Filament PF00038.16 KEG09326.1 - 0.6 9.5 36.9 2.8 7.3 15.3 2.7 1 1 1 2 2 2 0 Intermediate filament protein FlaC_arch PF05377.6 KEG09326.1 - 0.7 9.8 4.8 6.9 6.6 0.1 3.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) GAS PF13851.1 KEG09326.1 - 1.6 7.8 35.6 0.59 9.3 2.2 2.7 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.6 KEG09326.1 - 2.8 7.7 41.1 1.8 8.3 3.0 4.2 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) IncA PF04156.9 KEG09326.1 - 4.6 6.7 32.8 0.34 10.4 7.6 3.4 2 1 1 3 3 3 0 IncA protein RRM_1 PF00076.17 KEG09328.1 - 1.1e-35 121.0 0.0 1.9e-20 72.2 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG09328.1 - 5.4e-28 96.7 0.1 7.6e-15 54.6 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG09328.1 - 4.9e-16 58.3 0.0 7.1e-09 35.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KEG09328.1 - 0.00015 21.4 0.0 0.097 12.4 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KEG09328.1 - 0.13 12.1 0.0 0.7 9.7 0.0 2.1 2 0 0 2 2 2 0 RNA binding motif LRR_6 PF13516.1 KEG09329.1 - 0.042 13.9 0.0 1.8 8.8 0.0 3.1 3 0 0 3 3 3 0 Leucine Rich repeat Ras PF00071.17 KEG09331.1 - 1.2e-05 24.7 0.0 1.4e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEG09331.1 - 0.063 13.7 0.0 0.086 13.3 0.0 1.2 1 0 0 1 1 1 0 Miro-like protein SAM_1 PF00536.25 KEG09332.1 - 0.047 13.8 0.0 0.086 13.0 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Tn7_TnsC_Int PF11426.3 KEG09334.1 - 0.088 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Tn7 transposition regulator TnsC BK_channel_a PF03493.13 KEG09335.1 - 5.5e-15 55.1 0.0 1.1e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.11 KEG09335.1 - 9.9e-11 41.2 6.5 9.9e-11 41.2 4.5 2.2 2 1 0 2 2 2 1 Ion channel TrkA_C PF02080.16 KEG09335.1 - 0.00092 18.7 0.0 0.0022 17.5 0.0 1.6 1 0 0 1 1 1 1 TrkA-C domain ABC_tran PF00005.22 KEG09336.1 - 1.3e-16 61.1 0.0 3.5e-16 59.7 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 KEG09336.1 - 2.4e-06 27.6 2.0 5.2e-06 26.5 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 KEG09336.1 - 2.9e-06 26.9 3.0 1.5e-05 24.6 0.0 3.2 2 0 0 2 2 2 1 Part of AAA domain AAA_21 PF13304.1 KEG09336.1 - 9e-06 25.8 0.0 0.12 12.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KEG09336.1 - 0.001 19.2 0.0 0.0043 17.2 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KEG09336.1 - 0.002 17.8 0.3 0.016 14.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 KEG09336.1 - 0.0023 17.5 3.9 0.055 13.0 0.0 3.1 3 1 0 3 3 3 1 AAA domain AAA_17 PF13207.1 KEG09336.1 - 0.0031 18.3 0.0 0.011 16.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KEG09336.1 - 0.0036 16.9 0.0 0.0081 15.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_28 PF13521.1 KEG09336.1 - 0.0041 17.1 0.4 0.071 13.0 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.1 KEG09336.1 - 0.0075 16.1 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 KEG09336.1 - 0.0097 15.1 0.1 0.018 14.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA PF00004.24 KEG09336.1 - 0.012 15.8 0.1 0.18 11.9 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.14 KEG09336.1 - 0.015 14.5 0.0 1.5 8.0 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Arch_ATPase PF01637.13 KEG09336.1 - 0.016 14.9 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_18 PF13238.1 KEG09336.1 - 0.02 15.2 0.0 0.046 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KEG09336.1 - 0.035 13.9 1.1 0.37 10.6 0.0 3.1 4 0 0 4 4 3 0 AAA domain AAA_23 PF13476.1 KEG09336.1 - 0.041 14.2 0.0 0.07 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 KEG09336.1 - 0.05 12.5 0.1 0.15 10.9 0.1 1.8 1 1 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.1 KEG09336.1 - 0.055 12.8 3.5 0.2 11.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.10 KEG09336.1 - 0.063 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_29 PF13555.1 KEG09336.1 - 0.067 12.7 0.1 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.10 KEG09336.1 - 0.096 11.3 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein PRK PF00485.13 KEG09336.1 - 0.17 11.4 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_10 PF12846.2 KEG09336.1 - 0.27 10.6 0.0 0.69 9.2 0.0 1.7 1 0 0 1 1 1 0 AAA-like domain MRI PF15325.1 KEG09337.1 - 0.099 13.6 0.1 0.27 12.2 0.0 1.7 1 0 0 1 1 1 0 Modulator of retrovirus infection CRAL_TRIO PF00650.15 KEG09339.1 - 2.3e-28 98.7 0.0 3.1e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 KEG09339.1 - 8.2e-08 32.2 0.0 1.3e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KEG09339.1 - 1.8e-05 24.7 1.2 7.7e-05 22.7 0.1 2.5 3 0 0 3 3 3 1 CRAL/TRIO, N-terminal domain Noelin-1 PF12308.3 KEG09339.1 - 0.097 12.4 0.9 3 7.6 0.0 3.2 3 1 1 4 4 4 0 Neurogenesis glycoprotein Kelch_4 PF13418.1 KEG09340.1 - 3.8e-09 36.1 8.7 8.9e-05 22.1 0.0 5.5 5 0 0 5 5 5 2 Galactose oxidase, central domain PH PF00169.24 KEG09340.1 - 4.1e-07 30.1 4.3 0.0049 17.0 1.0 3.2 2 2 0 2 2 2 2 PH domain Kelch_6 PF13964.1 KEG09340.1 - 2.2e-06 27.6 1.2 1 9.6 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 KEG09340.1 - 1.8e-05 24.7 11.1 0.22 11.7 0.0 6.2 5 1 0 5 5 5 3 Galactose oxidase, central domain PH_8 PF15409.1 KEG09340.1 - 0.00011 22.1 3.0 0.11 12.6 0.0 2.7 2 1 0 2 2 2 2 Pleckstrin homology domain Kelch_5 PF13854.1 KEG09340.1 - 0.00033 20.5 13.7 0.24 11.3 0.0 5.5 6 1 0 6 6 6 1 Kelch motif PH_11 PF15413.1 KEG09340.1 - 0.0014 18.8 2.1 0.09 13.0 0.0 2.8 2 1 1 3 3 3 1 Pleckstrin homology domain Kelch_2 PF07646.10 KEG09340.1 - 0.11 12.3 6.5 9 6.2 0.9 4.1 4 0 0 4 4 4 0 Kelch motif Kelch_1 PF01344.20 KEG09340.1 - 0.14 11.7 14.2 2.3 7.8 3.5 4.5 5 0 0 5 5 5 0 Kelch motif DUF1796 PF08795.5 KEG09341.1 - 5.2e-42 143.3 0.0 7e-42 142.8 0.0 1.2 1 0 0 1 1 1 1 Putative papain-like cysteine peptidase (DUF1796) Pkinase PF00069.20 KEG09342.1 - 1.3e-29 103.1 0.0 1.1e-11 44.4 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 KEG09342.1 - 1.5e-12 47.1 0.0 3.1e-05 23.1 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase PseudoU_synth_1 PF01416.15 KEG09343.1 - 2.3e-25 89.0 0.0 2.9e-16 59.8 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase EmrE PF13536.1 KEG09344.1 - 0.048 13.8 0.2 0.068 13.3 0.1 1.2 1 0 0 1 1 1 0 Multidrug resistance efflux transporter Prefoldin_2 PF01920.15 KEG09345.1 - 1.1e-09 38.0 3.1 1.1e-09 38.0 2.1 1.8 2 1 0 2 2 2 1 Prefoldin subunit Tho2 PF11262.3 KEG09345.1 - 0.14 11.2 1.2 0.17 10.9 0.8 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF4164 PF13747.1 KEG09345.1 - 0.19 11.8 12.3 0.12 12.5 2.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Med30 PF11315.3 KEG09345.1 - 0.26 11.4 6.0 0.25 11.4 2.8 1.8 1 1 1 2 2 2 0 Mediator complex subunit 30 KxDL PF10241.4 KEG09345.1 - 0.3 11.0 7.3 0.13 12.1 2.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein TMCO5 PF14992.1 KEG09345.1 - 6.2 5.8 11.0 5.6 6.0 4.7 2.0 2 0 0 2 2 2 0 TMCO5 family Phage_Gp23 PF10669.4 KEG09345.1 - 7.9 6.6 6.7 42 4.2 2.2 2.2 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) MMR_HSR1 PF01926.18 KEG09346.1 - 3.5e-09 36.6 0.0 8.5e-08 32.1 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KEG09346.1 - 1.7e-05 24.7 0.0 0.00033 20.5 0.0 2.4 2 0 0 2 2 2 1 Dynamin family GTP_EFTU PF00009.22 KEG09346.1 - 3e-05 23.5 0.0 6.9e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KEG09346.1 - 0.00014 21.1 0.3 1.2 8.4 0.0 3.5 4 0 0 4 4 4 2 Ferrous iron transport protein B ATP_bind_1 PF03029.12 KEG09346.1 - 0.00042 19.9 0.0 0.005 16.4 0.0 2.5 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein DUF258 PF03193.11 KEG09346.1 - 0.0031 16.7 0.0 0.01 15.0 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Amastin PF07344.6 KEG09347.1 - 7.5e-40 136.0 9.9 9e-40 135.8 6.9 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF2781 PF10914.3 KEG09347.1 - 0.036 13.8 0.7 0.06 13.1 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) DUF962 PF06127.6 KEG09347.1 - 0.52 10.2 4.8 2.4 8.0 3.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF962) DUF1345 PF07077.6 KEG09347.1 - 1 8.8 5.9 0.074 12.5 0.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) E1-E2_ATPase PF00122.15 KEG09347.1 - 4.2 6.3 5.9 5.6 5.9 4.1 1.4 1 1 0 1 1 1 0 E1-E2 ATPase Keratin_assoc PF09775.4 KEG09347.1 - 4.4 6.8 11.0 0.082 12.4 2.8 1.6 2 0 0 2 2 2 0 Keratinocyte-associated protein 2 Amastin PF07344.6 KEG09349.1 - 5.6e-35 120.2 5.8 7.1e-35 119.9 4.0 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein TMEM37 PF15108.1 KEG09349.1 - 0.013 15.1 1.4 0.019 14.6 0.2 1.7 2 0 0 2 2 2 0 Voltage-dependent calcium channel gamma-like subunit protein family Tmemb_185A PF10269.4 KEG09349.1 - 0.028 14.0 1.4 0.044 13.3 0.5 1.5 2 0 0 2 2 2 0 Transmembrane Fragile-X-F protein Kinase-like PF14531.1 KEG09349.1 - 0.071 12.0 0.2 0.1 11.5 0.1 1.1 1 0 0 1 1 1 0 Kinase-like DUF456 PF04306.8 KEG09349.1 - 0.078 13.0 6.7 2 8.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF456) SNARE_assoc PF09335.6 KEG09349.1 - 0.14 12.3 0.0 0.14 12.3 0.0 2.4 3 1 0 3 3 3 0 SNARE associated Golgi protein DUF3040 PF11239.3 KEG09349.1 - 8 6.5 6.3 16 5.6 0.7 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3040) Epimerase PF01370.16 KEG09350.1 - 2e-35 122.3 0.0 2.4e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KEG09350.1 - 5.7e-08 31.9 0.0 1.6e-06 27.2 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 KEG09350.1 - 3.2e-07 29.3 0.0 4.2e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KEG09350.1 - 9.5e-05 22.3 0.0 0.00041 20.2 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KEG09350.1 - 0.0039 17.2 0.0 0.0059 16.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KEG09350.1 - 0.013 14.3 0.0 0.9 8.3 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KEG09350.1 - 0.032 13.1 0.0 0.8 8.5 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DUF43 PF01861.11 KEG09350.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF43 PfkB PF00294.19 KEG09351.1 - 8.8e-57 192.5 0.3 1.1e-56 192.2 0.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase 2OG-FeII_Oxy_2 PF13532.1 KEG09352.1 - 2.6e-14 53.4 0.0 3.9e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KEG09352.1 - 6.5e-07 29.5 0.0 2.2e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KEG09352.1 - 0.087 13.3 0.0 0.41 11.1 0.0 2.1 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily ATG16 PF08614.6 KEG09354.1 - 0.0044 16.8 35.3 0.0089 15.8 5.2 3.7 3 1 0 3 3 3 1 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 KEG09354.1 - 0.02 14.1 4.0 0.49 9.5 0.1 3.0 3 0 0 3 3 3 0 Reovirus sigma C capsid protein CCDC155 PF14662.1 KEG09354.1 - 0.26 10.8 45.9 0.017 14.7 7.6 3.9 4 1 0 4 4 4 0 Coiled-coil region of CCDC155 FlaC_arch PF05377.6 KEG09354.1 - 0.47 10.3 16.7 3.8 7.4 0.1 5.1 5 1 0 5 5 4 0 Flagella accessory protein C (FlaC) IFP_35_N PF07334.8 KEG09354.1 - 0.49 10.4 7.2 0.57 10.1 0.0 3.6 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus LPP PF04728.8 KEG09354.1 - 1.1 9.1 0.0 1.1 9.1 0.0 3.3 4 0 0 4 4 3 0 Lipoprotein leucine-zipper Filament PF00038.16 KEG09354.1 - 1.1 8.6 44.1 0.25 10.7 10.3 4.2 3 1 1 4 4 4 0 Intermediate filament protein NPV_P10 PF05531.7 KEG09354.1 - 1.3 9.3 11.1 27 5.1 0.0 4.4 5 0 0 5 5 4 0 Nucleopolyhedrovirus P10 protein DASH_Dad2 PF08654.5 KEG09354.1 - 2.3 8.2 9.6 1.7 8.6 0.0 3.6 3 1 0 4 4 4 0 DASH complex subunit Dad2 BLOC1_2 PF10046.4 KEG09354.1 - 2.5 8.2 17.6 2.5 8.3 0.1 5.2 4 2 2 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TLE_N PF03920.10 KEG09354.1 - 3.1 7.6 10.1 3.7 7.3 0.1 3.9 4 0 0 4 4 4 0 Groucho/TLE N-terminal Q-rich domain DivIVA PF05103.8 KEG09354.1 - 4.4 7.3 35.5 0.1 12.6 5.4 4.1 3 1 1 4 4 4 0 DivIVA protein Baculo_PEP_C PF04513.7 KEG09354.1 - 4.7 7.0 14.5 7.8 6.3 1.0 4.4 3 2 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DivIC PF04977.10 KEG09354.1 - 5.2 6.6 38.3 0.66 9.5 1.3 6.0 3 2 2 6 6 6 0 Septum formation initiator DUF4047 PF13256.1 KEG09354.1 - 6.1 6.8 16.6 13 5.8 0.2 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4047) DUF4200 PF13863.1 KEG09354.1 - 6.9 6.6 48.9 0.037 13.9 9.5 4.7 4 1 1 5 5 5 0 Domain of unknown function (DUF4200) HALZ PF02183.13 KEG09354.1 - 8.4 6.1 27.4 1.7 8.4 0.3 6.8 5 2 1 6 6 6 0 Homeobox associated leucine zipper bZIP_1 PF00170.16 KEG09354.1 - 8.9 6.3 36.1 0.44 10.5 0.3 6.5 4 2 2 6 6 6 0 bZIP transcription factor Ala_racemase_N PF01168.15 KEG09355.1 - 1.8e-33 115.9 0.0 2.7e-33 115.3 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Ala_racemase_C PF00842.16 KEG09355.1 - 4.9e-22 77.7 0.2 8.5e-22 76.9 0.1 1.4 1 0 0 1 1 1 1 Alanine racemase, C-terminal domain tRNA-synt_2d PF01409.15 KEG09355.1 - 0.052 12.7 0.1 0.092 11.9 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) UQ_con PF00179.21 KEG09356.1 - 2e-53 179.5 0.0 2.3e-53 179.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KEG09356.1 - 0.0013 18.5 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 KEG09356.1 - 0.016 14.9 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.8 KEG09356.1 - 0.083 12.5 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 UEV domain TFIIA PF03153.8 KEG09359.1 - 8.6 6.1 12.6 10 5.9 8.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ADP_PFK_GK PF04587.10 KEG09360.1 - 0.033 12.4 0.1 0.062 11.5 0.0 1.4 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region Mito_carr PF00153.22 KEG09362.1 - 1.1e-33 114.7 8.3 1.2e-19 69.7 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein AA_permease_2 PF13520.1 KEG09363.1 - 4.3e-36 124.3 47.1 6.3e-36 123.8 32.6 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KEG09363.1 - 2.6e-15 55.7 39.3 3.8e-15 55.2 27.2 1.3 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_3 PF00933.16 KEG09366.1 - 3.9e-92 308.4 0.0 7.9e-92 307.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEG09366.1 - 4.5e-58 196.4 0.0 1e-57 195.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KEG09366.1 - 1.9e-23 82.1 0.1 3.9e-23 81.1 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Gamma-thionin PF00304.15 KEG09367.1 - 0.17 11.9 0.4 0.17 11.9 0.3 2.0 3 0 0 3 3 3 0 Gamma-thionin family Sugar_tr PF00083.19 KEG09368.1 - 3.6e-91 306.0 29.4 1.3e-90 304.1 20.4 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEG09368.1 - 2.9e-12 45.9 34.3 5.6e-09 35.1 22.8 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily Arena_glycoprot PF00798.13 KEG09368.1 - 0.032 12.6 0.2 0.046 12.1 0.1 1.1 1 0 0 1 1 1 0 Arenavirus glycoprotein Paramecium_SA PF01508.11 KEG09368.1 - 2.1 8.6 11.7 0.43 10.8 3.4 2.4 1 1 1 2 2 2 0 Paramecium surface antigen domain PSI PF01437.20 KEG09368.1 - 6.3 7.0 11.7 21 5.3 8.1 1.9 1 1 0 1 1 1 0 Plexin repeat Steroid_dh PF02544.11 KEG09371.1 - 4e-05 23.4 0.8 0.001 18.8 0.2 2.6 1 1 1 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase cNMP_binding PF00027.24 KEG09374.1 - 6.9e-14 51.4 0.0 7.4e-08 32.0 0.0 3.1 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain DHC_N2 PF08393.8 KEG09374.1 - 0.36 9.2 0.0 0.59 8.5 0.0 1.2 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 PCI PF01399.22 KEG09375.1 - 1.6e-19 70.1 0.1 3e-19 69.2 0.1 1.5 1 0 0 1 1 1 1 PCI domain Rpn3_C PF08375.6 KEG09375.1 - 5.7e-19 68.2 2.2 1.3e-18 67.1 1.5 1.6 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal tRNA-synt_His PF13393.1 KEG09376.1 - 3.8e-40 137.8 0.0 7e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 KEG09376.1 - 5.5e-15 55.3 0.0 8.3e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KEG09376.1 - 1.8e-05 24.5 0.1 7.1e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain RRS1 PF04939.7 KEG09377.1 - 1.6e-48 164.3 6.5 2.1e-48 163.9 4.5 1.2 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Cyt-b5 PF00173.23 KEG09378.1 - 1e-13 50.8 0.0 2.1e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.19 KEG09378.1 - 6.6e-12 45.4 0.0 1.2e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KEG09378.1 - 6.6e-07 29.8 0.1 4.1e-06 27.3 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KEG09378.1 - 0.022 14.6 0.1 0.066 13.1 0.0 1.9 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Pkinase PF00069.20 KEG09379.1 - 8.2e-67 225.0 0.0 1.1e-66 224.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG09379.1 - 1.4e-42 145.5 0.0 1.9e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG09379.1 - 3.6e-07 29.4 0.0 0.00027 19.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.17 KEG09379.1 - 0.0029 17.0 0.0 0.0053 16.1 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KEG09379.1 - 0.014 15.1 0.6 0.094 12.4 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family BBS2_C PF14782.1 KEG09380.1 - 2.1e-51 174.8 0.0 3.7e-51 174.0 0.0 1.3 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal BBS2_N PF14781.1 KEG09380.1 - 2.8e-37 127.3 0.0 5.9e-37 126.3 0.0 1.6 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, N-terminal BBS2_Mid PF14783.1 KEG09380.1 - 6.5e-33 112.8 0.0 4e-32 110.2 0.0 2.3 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region FG-GAP PF01839.18 KEG09380.1 - 0.00087 18.9 0.0 0.0031 17.1 0.0 1.9 1 0 0 1 1 1 1 FG-GAP repeat VCBS PF13517.1 KEG09380.1 - 0.036 14.4 0.0 0.14 12.4 0.0 2.1 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella CHAP PF05257.11 KEG09381.1 - 1.8e-05 24.3 1.1 0.0012 18.4 0.3 2.4 2 1 0 2 2 2 2 CHAP domain CHAP PF05257.11 KEG09382.1 - 8.9e-05 22.1 2.2 0.0073 15.9 0.4 2.5 2 1 0 2 2 2 2 CHAP domain GYF PF02213.11 KEG09382.1 - 0.064 12.8 0.3 0.14 11.7 0.2 1.5 1 0 0 1 1 1 0 GYF domain Thioredoxin PF00085.15 KEG09384.1 - 0.001 18.7 0.0 0.0021 17.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin DnaJ PF00226.26 KEG09386.1 - 1.1e-09 37.9 0.2 1.9e-09 37.1 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ-X PF14308.1 KEG09386.1 - 7.6e-08 31.8 0.0 1.2e-06 27.9 0.0 2.1 1 1 1 2 2 2 1 X-domain of DnaJ-containing T4SS-DNA_transf PF02534.9 KEG09386.1 - 0.092 11.3 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Ribosomal_S21 PF01165.15 KEG09386.1 - 0.13 11.6 0.3 0.81 9.1 0.0 2.4 3 0 0 3 3 3 0 Ribosomal protein S21 Peptidase_C2 PF00648.16 KEG09388.1 - 3.6e-48 164.1 0.4 4.9e-48 163.6 0.3 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 KEG09388.1 - 3.9e-26 91.0 0.0 7.1e-26 90.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) AAA_14 PF13173.1 KEG09389.1 - 0.061 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Peptidase_C2 PF00648.16 KEG09390.1 - 1.4e-60 204.8 0.1 2.6e-60 203.9 0.0 1.5 2 0 0 2 2 2 1 Calpain family cysteine protease DUF1935 PF09149.5 KEG09390.1 - 8.9e-17 60.9 0.0 2e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF1935 PF09149.5 KEG09391.1 - 6.3e-23 80.7 1.9 7.4e-23 80.5 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.16 KEG09392.1 - 5.8e-26 91.1 0.0 6.7e-26 90.9 0.0 1.0 1 0 0 1 1 1 1 Calpain family cysteine protease C2 PF00168.25 KEG09394.1 - 0.044 13.6 0.0 0.28 11.0 0.0 2.3 1 1 0 1 1 1 0 C2 domain PTEN_C2 PF10409.4 KEG09395.1 - 1.9e-11 43.8 0.0 6.2e-11 42.1 0.0 1.8 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.15 KEG09395.1 - 2.6e-09 36.7 0.0 6.7e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KEG09395.1 - 2.1e-06 27.2 0.0 4.1e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KEG09395.1 - 0.00092 19.2 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 KEG09395.1 - 0.0019 18.4 0.0 0.0036 17.5 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family 2-Hacid_dh_C PF02826.14 KEG09396.1 - 7e-47 158.8 0.0 9.8e-47 158.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 KEG09396.1 - 0.0015 18.3 0.2 0.0035 17.2 0.1 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 KEG09396.1 - 0.0033 16.8 0.0 0.0089 15.4 0.0 1.7 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 KEG09396.1 - 0.0067 16.8 0.1 0.084 13.3 0.0 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 KEG09396.1 - 0.0082 16.1 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 KEG09396.1 - 0.011 15.7 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.14 KEG09397.1 - 6.5e-47 158.9 0.0 9.3e-47 158.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 KEG09397.1 - 0.001 18.9 0.1 0.0015 18.4 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.13 KEG09397.1 - 0.0026 17.7 0.0 0.0055 16.7 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain IlvN PF07991.7 KEG09397.1 - 0.0027 17.0 0.0 0.0038 16.5 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_10 PF13460.1 KEG09397.1 - 0.0051 16.8 0.0 0.0082 16.1 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding F420_oxidored PF03807.12 KEG09397.1 - 0.0097 16.3 0.0 0.022 15.1 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 KEG09397.1 - 0.11 11.9 0.0 0.76 9.2 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 KEG09397.1 - 0.15 12.5 0.2 0.44 10.9 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CcmH PF03918.9 KEG09398.1 - 0.27 10.2 3.6 0.34 9.8 0.0 3.1 4 1 1 5 5 5 0 Cytochrome C biogenesis protein Herpes_gE PF02480.11 KEG09398.1 - 0.68 8.1 6.8 0.72 8.0 0.0 2.9 3 0 0 3 3 3 0 Alphaherpesvirus glycoprotein E PBP1_TM PF14812.1 KEG09399.1 - 0.58 10.5 13.7 0.24 11.7 5.3 3.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Daxx PF03344.10 KEG09399.1 - 0.92 7.9 10.4 1.7 7.0 7.2 1.3 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 KEG09399.1 - 3.3 5.6 8.8 5.3 4.9 6.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.2 KEG09399.1 - 3.6 5.1 4.4 5.2 4.6 3.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PEX11 PF05648.9 KEG09400.1 - 0.009 15.2 0.5 0.076 12.2 0.0 2.1 2 0 0 2 2 2 1 Peroxisomal biogenesis factor 11 (PEX11) DNA_methylase PF00145.12 KEG09401.1 - 3.8e-08 32.8 0.2 0.00017 20.8 0.0 2.1 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase Ribosomal_S25 PF03297.10 KEG09402.1 - 6.7e-41 138.5 4.8 7.5e-41 138.4 3.3 1.0 1 0 0 1 1 1 1 S25 ribosomal protein ATP-synt_ab PF00006.20 KEG09403.1 - 1.4e-64 217.5 0.1 5.6e-64 215.5 0.0 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KEG09403.1 - 6e-23 81.4 0.6 1e-22 80.7 0.4 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KEG09403.1 - 5e-13 49.0 0.2 1.2e-12 47.8 0.2 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_25 PF13481.1 KEG09403.1 - 0.0019 17.6 0.3 0.0072 15.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KEG09403.1 - 0.0088 16.2 0.1 0.056 13.6 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 KEG09403.1 - 0.02 14.0 0.1 0.036 13.1 0.0 1.4 1 0 0 1 1 1 0 KaiC DUF258 PF03193.11 KEG09403.1 - 0.06 12.5 0.1 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF2075 PF09848.4 KEG09403.1 - 0.34 9.8 1.4 3.2 6.6 0.2 2.4 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2075) LMBR1 PF04791.11 KEG09404.1 - 8.1e-36 123.6 25.5 2.1e-21 76.0 3.9 2.0 2 0 0 2 2 2 2 LMBR1-like membrane protein eIF-1a PF01176.14 KEG09404.1 - 0.077 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 Mec-17 PF05301.6 KEG09405.1 - 3.4e-33 114.1 0.0 5.3e-33 113.5 0.0 1.2 1 0 0 1 1 1 1 Touch receptor neuron protein Mec-17 SBP_bac_3 PF00497.15 KEG09406.1 - 0.04 13.1 0.0 0.62 9.2 0.0 2.0 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 GHL15 PF14885.1 KEG09406.1 - 0.29 11.3 2.2 0.25 11.5 0.2 1.8 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase family 15 Aldedh PF00171.17 KEG09407.1 - 3.2e-181 602.7 0.0 3.6e-181 602.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KEG09407.1 - 0.0005 18.9 0.0 0.0014 17.4 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) BNR_3 PF13859.1 KEG09408.1 - 4.4e-80 269.0 0.0 6.8e-80 268.4 0.0 1.3 1 0 0 1 1 1 1 BNR repeat-like domain BNR_2 PF13088.1 KEG09408.1 - 1.7e-18 66.9 0.8 1.1e-17 64.3 0.2 2.3 2 1 0 2 2 2 1 BNR repeat-like domain Laminin_G_3 PF13385.1 KEG09408.1 - 9.5e-13 48.6 2.2 1.7e-12 47.8 0.0 2.4 2 1 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily BNR PF02012.15 KEG09408.1 - 3.1e-05 23.1 14.9 0.15 12.0 0.1 5.2 4 0 0 4 4 4 3 BNR/Asp-box repeat Kelch_6 PF13964.1 KEG09408.1 - 3 8.1 6.3 2.4 8.4 0.2 3.3 4 0 0 4 4 4 0 Kelch motif Methyltransf_5 PF01795.14 KEG09409.1 - 2.1e-28 99.5 0.0 3.1e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 MraW methylase family Methyltransf_26 PF13659.1 KEG09409.1 - 1.3e-05 25.1 0.1 8.7e-05 22.5 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEG09409.1 - 0.00013 21.6 0.0 0.0091 15.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 KEG09409.1 - 0.0045 17.8 0.0 0.034 14.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEG09409.1 - 0.045 14.3 0.0 0.95 10.0 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain UPF0546 PF10639.4 KEG09410.1 - 2.5e-35 120.7 1.6 2.9e-35 120.4 1.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 EamA PF00892.15 KEG09410.1 - 3.2e-06 27.2 5.6 7e-06 26.1 2.2 2.0 2 0 0 2 2 2 1 EamA-like transporter family DUF2955 PF11168.3 KEG09410.1 - 0.11 12.1 5.6 0.18 11.4 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2955) EmrE PF13536.1 KEG09410.1 - 3.1 8.0 7.4 7 6.8 5.1 1.8 1 1 0 1 1 1 0 Multidrug resistance efflux transporter Ribosomal_S9 PF00380.14 KEG09411.1 - 9.2e-07 29.1 0.0 1.9e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DUF1900 PF08954.6 KEG09412.1 - 1.1e-42 144.8 0.0 2.3e-42 143.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) WD40 PF00400.27 KEG09412.1 - 4.3e-19 67.5 3.7 3.1e-05 23.6 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF1899 PF08953.6 KEG09412.1 - 0.00029 20.4 0.0 0.00073 19.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) Cu-oxidase_2 PF07731.9 KEG09412.1 - 0.037 13.5 0.0 0.093 12.2 0.0 1.6 1 0 0 1 1 1 0 Multicopper oxidase Daxx PF03344.10 KEG09414.1 - 1.5 7.2 11.6 1.5 7.2 8.1 1.1 1 0 0 1 1 1 0 Daxx Family TEX19 PF15553.1 KEG09414.1 - 1.7 8.4 7.5 2 8.2 5.2 1.1 1 0 0 1 1 1 0 Testis-expressed protein 19 Cyclin_N PF00134.18 KEG09415.1 - 1.1e-25 89.5 1.7 6.4e-25 87.1 0.2 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain DUF445 PF04286.7 KEG09418.1 - 0.017 14.6 18.9 0.029 13.9 13.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) UPF0220 PF05255.6 KEG09419.1 - 7.9e-15 54.4 2.3 2.3e-14 52.9 1.6 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF4499 PF14934.1 KEG09419.1 - 0.037 13.9 0.2 0.063 13.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4499) Bax1-I PF01027.15 KEG09419.1 - 0.038 13.5 3.6 0.051 13.1 2.5 1.4 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Na_Ca_ex PF01699.19 KEG09419.1 - 0.075 12.6 4.3 0.11 12.0 3.0 1.4 1 0 0 1 1 1 0 Sodium/calcium exchanger protein DUF165 PF02592.10 KEG09419.1 - 0.075 13.1 0.9 0.12 12.5 0.6 1.3 1 0 0 1 1 1 0 Uncharacterized ACR, YhhQ family COG1738 Nucleos_tra2_C PF07662.8 KEG09419.1 - 0.11 11.9 2.1 0.19 11.1 1.5 1.4 1 1 0 1 1 1 0 Na+ dependent nucleoside transporter C-terminus Pro_isomerase PF00160.16 KEG09421.1 - 4.3e-22 78.9 0.0 5.3e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CmcI PF04989.7 KEG09422.1 - 9.4e-41 139.3 0.1 4.8e-40 137.0 0.0 1.8 1 1 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_24 PF13578.1 KEG09422.1 - 0.002 18.9 0.0 0.0042 17.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain TylF PF05711.6 KEG09422.1 - 0.025 13.6 0.1 1.5 7.8 0.0 2.1 2 0 0 2 2 2 0 Macrocin-O-methyltransferase (TylF) LIM PF00412.17 KEG09424.1 - 0.00012 22.0 13.5 0.0015 18.5 8.5 2.5 2 1 0 2 2 2 1 LIM domain ACC_epsilon PF13822.1 KEG09424.1 - 2.9 8.2 6.1 6.1 7.2 4.2 1.6 1 1 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit Peptidase_C54 PF03416.14 KEG09425.1 - 7.1e-41 140.1 0.0 2.1e-39 135.3 0.0 2.0 1 1 0 1 1 1 1 Peptidase family C54 DUF70 PF01901.11 KEG09425.1 - 0.12 11.4 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF70 zf-C2H2_jaz PF12171.3 KEG09426.1 - 9.2e-13 47.9 27.4 0.00013 21.9 0.1 6.3 7 0 0 7 7 6 4 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 KEG09426.1 - 1.2e-11 44.5 41.2 5.1e-05 23.3 3.3 7.3 7 0 0 7 7 7 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 KEG09426.1 - 2.6e-11 43.1 55.0 0.022 15.0 0.0 8.7 9 0 0 9 9 8 6 Zinc finger, C2H2 type zf-met PF12874.2 KEG09426.1 - 1.2e-09 38.0 25.5 0.0034 17.5 0.1 7.0 7 1 0 7 7 7 4 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 KEG09426.1 - 4e-09 36.1 49.9 0.049 13.9 0.1 8.4 8 0 0 8 8 8 6 C2H2-type zinc finger zf-met2 PF12907.2 KEG09426.1 - 9.5e-06 25.4 28.0 0.0085 16.0 0.3 6.9 6 1 1 7 7 7 3 Zinc-binding zf-C2H2_2 PF12756.2 KEG09426.1 - 3e-05 24.0 28.5 1.1 9.3 0.1 7.0 3 2 3 6 6 6 3 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 KEG09426.1 - 0.00025 20.8 1.8 0.11 12.4 0.0 6.5 7 0 0 7 7 7 3 C2H2-type zinc finger DUF629 PF04780.7 KEG09426.1 - 0.012 14.2 21.0 0.33 9.4 3.5 5.2 4 1 2 6 6 6 0 Protein of unknown function (DUF629) zf-H2C2_2 PF13465.1 KEG09426.1 - 0.034 14.4 0.3 0.034 14.4 0.2 8.3 9 2 0 9 9 9 0 Zinc-finger double domain zf-C2HC_2 PF13913.1 KEG09426.1 - 0.12 12.0 0.0 0.12 12.0 0.0 5.1 6 0 0 6 6 5 0 zinc-finger of a C2HC-type UCH_1 PF13423.1 KEG09428.1 - 3.9e-27 95.4 0.0 7.9e-27 94.4 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 KEG09428.1 - 8.2e-23 81.4 0.0 2.1e-22 80.1 0.0 1.8 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 KEG09428.1 - 0.17 11.3 0.0 0.4 10.1 0.0 1.5 1 0 0 1 1 1 0 3'-5' exonuclease DUF1679 PF07914.6 KEG09429.1 - 0.19 10.3 0.0 0.26 9.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) MatE PF01554.13 KEG09431.1 - 1.8e-29 102.4 26.2 2.7e-17 62.8 7.0 2.3 2 0 0 2 2 2 2 MatE 3Beta_HSD PF01073.14 KEG09433.1 - 7e-39 133.2 0.0 9.1e-39 132.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KEG09433.1 - 5.8e-27 94.6 0.0 7.7e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEG09433.1 - 9.2e-14 51.8 0.0 1.3e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KEG09433.1 - 1.7e-13 50.1 0.1 4e-11 42.3 0.1 2.2 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 KEG09433.1 - 1.6e-11 43.6 0.0 3.2e-11 42.6 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KEG09433.1 - 9.6e-09 34.5 0.0 1.7e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 KEG09433.1 - 8.2e-07 28.5 0.0 1.3e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 KEG09433.1 - 1.9e-06 27.8 0.2 6.5e-06 26.1 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEG09433.1 - 0.00015 21.5 0.1 0.00055 19.6 0.1 1.9 2 1 0 2 2 2 1 KR domain Saccharop_dh PF03435.13 KEG09433.1 - 0.0071 15.3 0.0 0.012 14.5 0.0 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 KEG09433.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 KEG09433.1 - 0.17 11.2 0.9 0.31 10.3 0.6 1.5 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Peptidase_S9 PF00326.16 KEG09434.1 - 4.6e-35 120.7 0.0 8e-35 119.9 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.10 KEG09434.1 - 8.5e-23 80.5 0.0 1.5e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Glyco_hydro_31 PF01055.21 KEG09436.1 - 1.9e-93 313.6 0.0 2.3e-93 313.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 IQ PF00612.22 KEG09439.1 - 9e-10 37.3 20.4 0.00048 19.5 0.4 4.3 4 0 0 4 4 4 3 IQ calmodulin-binding motif His_Phos_1 PF00300.17 KEG09440.1 - 3.1e-16 59.8 0.7 1.2e-15 57.9 0.5 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Peptidase_C58 PF03543.9 KEG09440.1 - 0.063 12.7 0.3 0.11 11.9 0.2 1.4 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen RCC1 PF00415.13 KEG09441.1 - 2.3e-30 104.5 15.2 1.5e-08 34.6 0.0 7.8 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KEG09441.1 - 1.1e-18 66.2 27.8 1.8e-06 27.4 0.7 7.5 6 1 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.1 KEG09441.1 - 0.011 15.5 0.9 16 5.2 0.1 3.4 2 1 1 3 3 3 0 SUKH-3 immunity protein TMF_DNA_bd PF12329.3 KEG09442.1 - 0.00016 21.4 25.9 1 9.2 0.5 5.9 3 2 2 5 5 5 4 TATA element modulatory factor 1 DNA binding Atg14 PF10186.4 KEG09442.1 - 0.00042 19.3 11.4 0.0021 17.0 4.4 2.4 1 1 1 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 Reo_sigmaC PF04582.7 KEG09442.1 - 0.00098 18.3 1.1 0.39 9.8 0.2 3.0 2 1 0 3 3 3 1 Reovirus sigma C capsid protein IncA PF04156.9 KEG09442.1 - 0.0068 16.0 24.5 0.39 10.2 10.2 3.6 2 1 0 3 3 3 2 IncA protein DUF869 PF05911.6 KEG09442.1 - 0.19 9.9 23.4 0.15 10.2 0.9 3.0 2 1 1 3 3 3 0 Plant protein of unknown function (DUF869) DUF4618 PF15397.1 KEG09442.1 - 0.32 10.3 6.8 10 5.3 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4618) DUF3552 PF12072.3 KEG09442.1 - 0.33 10.1 22.8 0.6 9.2 8.7 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) SDH_alpha PF03313.10 KEG09442.1 - 0.65 8.9 6.5 0.92 8.4 0.3 2.4 2 0 0 2 2 2 0 Serine dehydratase alpha chain SlyX PF04102.7 KEG09442.1 - 2.7 8.4 13.1 31 5.0 0.0 4.9 3 2 2 5 5 5 0 SlyX Phage_GP20 PF06810.6 KEG09442.1 - 3.9 6.8 22.3 1.4 8.3 0.4 3.1 3 1 0 3 3 3 0 Phage minor structural protein GP20 KLRAQ PF10205.4 KEG09442.1 - 7.3 6.6 13.7 2.2 8.3 3.5 3.0 2 1 1 3 3 3 0 Predicted coiled-coil domain-containing protein APG6 PF04111.7 KEG09442.1 - 7.5 5.5 22.7 3.2 6.7 7.0 3.1 3 0 0 3 3 3 0 Autophagy protein Apg6 Mnd1 PF03962.10 KEG09442.1 - 8 6.0 22.9 0.74 9.4 2.8 3.5 3 1 1 4 4 4 0 Mnd1 family Vfa1 PF08432.5 KEG09443.1 - 0.0011 18.9 8.2 0.0014 18.6 5.7 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 DUF3140 PF11338.3 KEG09443.1 - 0.011 15.8 3.0 0.017 15.2 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) Herpes_UL6 PF01763.11 KEG09443.1 - 0.06 11.5 5.5 0.066 11.3 3.8 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF4200 PF13863.1 KEG09443.1 - 0.15 12.0 21.3 0.2 11.6 14.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) SpecificRecomb PF10136.4 KEG09443.1 - 0.22 9.5 2.3 0.26 9.2 1.6 1.0 1 0 0 1 1 1 0 Site-specific recombinase Atg14 PF10186.4 KEG09443.1 - 0.53 9.1 13.8 0.79 8.6 9.6 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 KEG09443.1 - 0.59 9.1 17.0 0.73 8.8 11.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 MCC-bdg_PDZ PF10506.4 KEG09443.1 - 1.1 9.1 7.3 0.19 11.5 1.0 2.3 2 1 1 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome ADIP PF11559.3 KEG09443.1 - 2 8.3 21.9 8.2 6.3 15.2 1.8 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Baculo_p24 PF05073.7 KEG09443.1 - 2.8 7.4 7.3 3.8 7.0 5.0 1.1 1 0 0 1 1 1 0 Baculovirus P24 capsid protein V_ATPase_I PF01496.14 KEG09443.1 - 3.5 5.3 7.9 4.1 5.1 5.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Jnk-SapK_ap_N PF09744.4 KEG09443.1 - 5.3 7.0 14.3 7.2 6.5 9.9 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF2868 PF11067.3 KEG09443.1 - 5.7 5.9 8.5 7.1 5.6 5.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Metal_resist PF13801.1 KEG09443.1 - 6.1 6.8 17.9 0.24 11.3 5.8 2.1 1 1 1 2 2 2 0 Heavy-metal resistance DUF342 PF03961.8 KEG09443.1 - 7 4.9 8.7 8.7 4.6 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2347 PF09804.4 KEG09443.1 - 7.1 5.8 6.9 9.6 5.3 4.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) LTXXQ PF07813.7 KEG09443.1 - 9.1 6.8 18.4 21 5.6 12.7 1.7 1 1 0 1 1 1 0 LTXXQ motif family protein PKD PF00801.15 KEG09444.1 - 0.091 12.5 0.2 0.4 10.4 0.0 2.1 2 0 0 2 2 2 0 PKD domain OmpH PF03938.9 KEG09444.1 - 0.65 9.9 5.1 0.84 9.5 1.7 2.3 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) DMPK_coil PF08826.5 KEG09444.1 - 0.66 9.9 7.4 3.1 7.7 0.0 4.2 4 0 0 4 4 4 0 DMPK coiled coil domain like TPR_11 PF13414.1 KEG09445.1 - 6.8e-18 64.0 10.2 0.00018 21.1 0.0 5.8 4 1 1 5 5 5 5 TPR repeat TPR_16 PF13432.1 KEG09445.1 - 6.2e-16 58.6 12.3 3.1e-07 30.8 3.2 5.7 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 KEG09445.1 - 1.3e-11 44.6 0.0 9.1e-05 22.7 0.0 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEG09445.1 - 2e-10 40.4 17.5 0.014 15.2 0.8 6.2 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 KEG09445.1 - 2.4e-10 40.1 20.6 0.0002 21.6 0.1 9.0 5 3 5 10 10 9 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEG09445.1 - 6.4e-10 38.1 10.2 0.025 14.4 0.0 8.0 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_1 PF00515.23 KEG09445.1 - 1.3e-08 34.0 4.1 0.12 12.0 0.0 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 KEG09445.1 - 3.2e-07 29.6 0.2 1.7 8.6 0.0 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 KEG09445.1 - 5.8e-06 26.0 0.4 0.087 13.0 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 KEG09445.1 - 6.2e-05 23.0 7.7 0.046 13.8 0.6 3.9 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KEG09445.1 - 0.00041 19.9 6.8 1.3 9.0 0.0 5.9 7 0 0 7 7 4 1 Tetratricopeptide repeat TPR_21 PF09976.4 KEG09445.1 - 0.00086 19.2 0.1 0.00086 19.2 0.1 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 KEG09445.1 - 0.0012 18.0 3.3 0.31 10.0 0.0 3.4 3 2 0 3 3 3 2 Tetratricopeptide repeat NARP1 PF12569.3 KEG09445.1 - 0.0046 15.7 0.1 0.076 11.7 0.1 2.2 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 Coatomer_E PF04733.9 KEG09445.1 - 0.0056 15.9 0.0 0.012 14.8 0.0 1.5 1 0 0 1 1 1 1 Coatomer epsilon subunit DUF2065 PF09838.4 KEG09445.1 - 0.14 11.8 0.1 3.7 7.3 0.1 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2065) TPR_6 PF13174.1 KEG09445.1 - 0.15 12.6 5.7 43 4.8 0.0 5.2 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 KEG09445.1 - 0.36 10.7 6.6 29 4.6 0.4 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat La PF05383.12 KEG09446.1 - 6.2e-22 77.1 0.1 1.3e-21 76.1 0.1 1.6 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 KEG09446.1 - 8.7e-09 34.8 0.0 4.7e-08 32.5 0.0 2.3 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG09446.1 - 2.9e-08 33.5 0.0 2.8e-07 30.3 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KEG09446.1 - 9.9e-05 22.1 7.4 0.0039 17.0 0.3 3.1 2 1 0 2 2 2 2 RNA binding motif RRM_5 PF13893.1 KEG09446.1 - 0.00049 19.8 0.0 0.034 14.0 0.0 2.8 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SseB_C PF14581.1 KEG09446.1 - 0.019 14.7 0.1 0.29 11.0 0.0 2.5 2 1 0 2 2 2 0 SseB protein C-terminal domain API5 PF05918.6 KEG09446.1 - 0.052 12.0 6.9 0.011 14.3 2.4 1.5 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) Enkurin PF13864.1 KEG09446.1 - 0.33 11.1 8.8 1.6 8.9 1.1 2.6 2 0 0 2 2 2 0 Calmodulin-binding Biotin_lipoyl PF00364.17 KEG09447.1 - 1.7e-19 69.2 0.2 6.4e-15 54.5 0.1 2.5 1 1 1 2 2 2 2 Biotin-requiring enzyme HlyD_3 PF13437.1 KEG09447.1 - 0.05 13.9 0.3 0.11 12.8 0.2 1.5 1 0 0 1 1 1 0 HlyD family secretion protein E3_binding PF02817.12 KEG09447.1 - 0.056 13.0 0.1 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 e3 binding domain NAD_binding_2 PF03446.10 KEG09447.1 - 0.19 11.5 1.4 1.7 8.4 0.2 2.2 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase TSC22 PF01166.13 KEG09448.1 - 0.00058 19.7 2.6 0.0031 17.4 1.8 2.2 1 0 0 1 1 1 1 TSC-22/dip/bun family IncA PF04156.9 KEG09448.1 - 0.0037 16.8 8.3 0.0037 16.8 5.7 2.4 2 0 0 2 2 2 1 IncA protein bZIP_1 PF00170.16 KEG09448.1 - 0.012 15.5 4.3 0.012 15.5 3.0 2.4 2 0 0 2 2 2 0 bZIP transcription factor TPR_MLP1_2 PF07926.7 KEG09448.1 - 0.012 15.3 2.0 0.012 15.3 1.4 2.7 2 2 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF972 PF06156.8 KEG09448.1 - 0.054 13.8 0.4 0.054 13.8 0.3 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF972) APG6 PF04111.7 KEG09448.1 - 0.054 12.5 17.1 0.028 13.4 2.1 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 WAC_Acf1_DNA_bd PF10537.4 KEG09448.1 - 0.17 12.0 1.4 0.41 10.8 1.0 1.6 1 0 0 1 1 1 0 ATP-utilising chromatin assembly and remodelling N-terminal TBPIP PF07106.8 KEG09448.1 - 2.8 7.4 14.5 0.065 12.7 2.6 2.4 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4172 PF13776.1 KEG09448.1 - 3.2 7.9 5.9 1.3 9.2 1.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4172) Ins134_P3_kin PF05770.6 KEG09449.1 - 1e-06 28.0 0.0 0.11 11.5 0.0 3.2 3 0 0 3 3 3 3 Inositol 1, 3, 4-trisphosphate 5/6-kinase Pro_isomerase PF00160.16 KEG09450.1 - 0.02 15.1 0.0 0.024 14.8 0.0 1.2 1 0 0 1 1 1 0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CENP-K PF11802.3 KEG09452.1 - 0.00021 20.6 0.4 0.00021 20.6 0.3 3.1 2 2 1 3 3 3 1 Centromere-associated protein K HrpA_pilin PF09589.5 KEG09452.1 - 0.014 15.8 0.0 0.98 9.8 0.0 3.2 2 1 0 2 2 2 0 HrpA pilus formation protein Reo_sigmaC PF04582.7 KEG09452.1 - 4.3 6.4 9.8 1.2 8.2 2.9 2.4 2 0 0 2 2 2 0 Reovirus sigma C capsid protein OmpH PF03938.9 KEG09453.1 - 0.00043 20.2 4.2 0.00088 19.2 2.9 1.5 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) Phage_GPO PF05929.6 KEG09453.1 - 0.0061 15.8 1.7 0.011 14.9 1.2 1.3 1 0 0 1 1 1 1 Phage capsid scaffolding protein (GPO) serine peptidase DUF3552 PF12072.3 KEG09453.1 - 0.013 14.7 9.3 0.034 13.3 6.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Ax_dynein_light PF10211.4 KEG09453.1 - 0.033 14.0 7.0 0.056 13.2 4.9 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain DUF4618 PF15397.1 KEG09453.1 - 0.052 12.8 5.0 0.089 12.1 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DUF2762 PF10960.3 KEG09453.1 - 0.19 11.4 2.8 24 4.7 0.7 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2762) Nup88 PF10168.4 KEG09453.1 - 0.46 8.2 4.9 0.71 7.6 2.2 1.8 2 0 0 2 2 2 0 Nuclear pore component Mnd1 PF03962.10 KEG09453.1 - 0.5 9.9 7.7 0.94 9.1 5.3 1.4 1 0 0 1 1 1 0 Mnd1 family Nup54 PF13874.1 KEG09453.1 - 5.7 6.6 13.3 14 5.2 9.2 1.7 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Ank_2 PF12796.2 KEG09454.1 - 5.8e-09 36.1 0.0 7.6e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEG09454.1 - 1.7e-06 28.4 0.0 5.3e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 KEG09454.1 - 3e-05 23.5 0.0 0.027 14.2 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 KEG09454.1 - 0.00033 20.6 0.0 0.022 14.9 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 KEG09454.1 - 0.0016 18.6 0.1 0.15 12.3 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Rossmann-like PF10727.4 KEG09454.1 - 0.15 11.7 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Rossmann-like domain FAD_binding_7 PF03441.9 KEG09455.1 - 5.1e-43 147.2 0.1 7.6e-43 146.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 KEG09455.1 - 1.1e-19 70.7 0.1 3.8e-19 69.0 0.0 1.9 2 0 0 2 2 2 1 DNA photolyase zf-rbx1 PF12678.2 KEG09456.1 - 1.8e-13 50.4 1.2 1.8e-13 50.4 0.8 1.7 2 0 0 2 2 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KEG09456.1 - 5.7e-12 45.2 4.4 1.2e-10 41.0 1.1 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KEG09456.1 - 9.1e-06 25.2 1.5 3.2e-05 23.4 1.0 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KEG09456.1 - 1.1e-05 25.2 0.9 2.5e-05 24.0 0.1 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 KEG09456.1 - 1.4e-05 25.0 0.9 1.4e-05 25.0 0.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEG09456.1 - 2.1e-05 24.1 3.2 5e-05 22.8 0.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEG09456.1 - 0.00049 19.7 1.4 0.001 18.7 0.3 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KEG09456.1 - 0.0028 17.3 0.5 0.0028 17.3 0.3 1.9 2 0 0 2 2 1 1 RING-type zinc-finger YjbE PF11106.3 KEG09456.1 - 0.016 15.1 2.3 0.016 15.1 1.6 3.0 4 1 0 4 4 3 0 Exopolysaccharide production protein YjbE zf-RING_4 PF14570.1 KEG09456.1 - 0.029 13.9 2.3 0.031 13.8 0.4 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 KEG09456.1 - 0.094 12.6 2.0 0.26 11.1 0.5 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.6 KEG09456.1 - 0.13 12.3 2.7 0.11 12.5 0.7 1.7 2 0 0 2 2 1 0 RING-like domain FANCL_C PF11793.3 KEG09456.1 - 0.14 12.1 4.5 0.65 9.9 3.1 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 KEG09456.1 - 0.64 10.1 5.4 1.5 8.9 1.5 2.4 2 0 0 2 2 2 0 RING-variant domain K_channel_TID PF07941.6 KEG09457.1 - 0.71 10.1 4.1 0.35 11.1 1.3 1.6 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain CHASE PF03924.8 KEG09458.1 - 0.003 16.8 0.0 0.0059 15.8 0.0 1.4 1 0 0 1 1 1 1 CHASE domain Pkinase PF00069.20 KEG09459.1 - 1.3e-34 119.5 0.2 1.9e-14 53.4 0.0 4.0 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 KEG09459.1 - 9e-11 41.3 0.1 4.2e-06 26.0 0.0 4.0 4 0 0 4 4 4 2 Protein tyrosine kinase Kinase-like PF14531.1 KEG09459.1 - 0.0062 15.5 0.4 0.11 11.4 0.0 2.4 3 0 0 3 3 3 1 Kinase-like Pkinase PF00069.20 KEG09460.1 - 1.6e-09 37.2 0.1 9.1e-05 21.7 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain CHRD PF07452.7 KEG09461.1 - 0.033 14.7 0.3 1.5 9.4 0.0 2.6 2 1 1 3 3 3 0 CHRD domain RRM_5 PF13893.1 KEG09461.1 - 0.062 13.1 0.0 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pet191_N PF10203.4 KEG09462.1 - 0.00041 20.3 4.6 0.038 14.0 0.4 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase assembly protein PET191 DUF2018 PF09442.5 KEG09462.1 - 0.078 13.5 0.1 0.12 12.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2018) Toxin_13 PF07822.6 KEG09462.1 - 0.3 11.0 3.6 0.41 10.5 2.2 1.6 1 1 0 1 1 1 0 Neurotoxin B-IV-like protein CHCH PF06747.8 KEG09462.1 - 1.3 9.0 8.6 0.24 11.3 1.8 2.5 3 0 0 3 3 3 0 CHCH domain Cmc1 PF08583.5 KEG09462.1 - 3.3 7.5 6.6 2 8.2 1.2 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like FtsJ PF01728.14 KEG09463.1 - 0.00054 19.9 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 KEG09463.1 - 0.045 13.4 0.0 0.086 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_S28 PF05577.7 KEG09464.1 - 6.5e-56 189.7 4.5 1.5e-55 188.5 3.1 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.6 KEG09464.1 - 9.6e-08 30.8 0.6 1.8e-07 30.0 0.0 1.6 2 0 0 2 2 2 1 PS-10 peptidase S37 Peptidase_S9 PF00326.16 KEG09464.1 - 6.2e-05 22.3 0.1 0.00011 21.4 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KEG09464.1 - 7.2e-05 22.7 4.6 0.00015 21.6 1.8 2.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEG09464.1 - 0.00016 21.3 2.0 0.00025 20.6 1.4 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF4355 PF14265.1 KEG09465.1 - 0.0022 17.9 3.9 0.0026 17.6 2.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4355) F-112 PF09645.5 KEG09465.1 - 0.0085 15.9 0.3 0.0095 15.8 0.2 1.2 1 0 0 1 1 1 1 F-112 protein Sec8_exocyst PF04048.9 KEG09465.1 - 0.012 15.2 0.2 0.015 14.9 0.1 1.1 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain BRF1 PF07741.8 KEG09465.1 - 0.012 15.7 0.3 0.013 15.7 0.2 1.1 1 0 0 1 1 1 0 Brf1-like TBP-binding domain BLOC1_2 PF10046.4 KEG09465.1 - 0.013 15.5 1.3 0.018 15.1 0.9 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Drf_FH3 PF06367.11 KEG09465.1 - 0.018 14.4 0.4 0.018 14.4 0.2 1.2 1 0 0 1 1 1 0 Diaphanous FH3 Domain MIF4G_like_2 PF09090.6 KEG09465.1 - 0.032 13.4 0.7 0.034 13.3 0.5 1.0 1 0 0 1 1 1 0 MIF4G like Mst1_SARAH PF11629.3 KEG09465.1 - 0.072 12.9 4.8 3.2 7.6 0.0 2.2 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 V_ATPase_I PF01496.14 KEG09465.1 - 0.1 10.4 0.8 0.093 10.5 0.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4337 PF14235.1 KEG09465.1 - 0.13 12.1 1.0 0.15 11.9 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Ima1_N PF09779.4 KEG09465.1 - 0.13 12.7 0.4 0.16 12.4 0.3 1.1 1 0 0 1 1 1 0 Ima1 N-terminal domain FliD_N PF02465.13 KEG09465.1 - 0.14 12.5 0.2 0.26 11.6 0.1 1.4 2 0 0 2 2 1 0 Flagellar hook-associated protein 2 N-terminus CDI PF02234.14 KEG09465.1 - 0.14 11.9 6.8 0.33 10.7 0.3 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor DUF972 PF06156.8 KEG09465.1 - 0.16 12.3 3.5 0.21 11.9 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) HDAC4_Gln PF12203.3 KEG09465.1 - 0.19 11.6 13.6 0.25 11.3 9.4 1.1 1 0 0 1 1 1 0 Glutamine rich N terminal domain of histone deacetylase 4 OmpH PF03938.9 KEG09465.1 - 0.24 11.3 4.8 0.32 10.9 3.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SAE2 PF08573.5 KEG09465.1 - 0.25 12.0 3.0 0.31 11.7 2.1 1.1 1 0 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus CR6_interact PF10147.4 KEG09465.1 - 0.35 10.1 5.7 0.43 9.8 3.9 1.1 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 HAUS6_N PF14661.1 KEG09465.1 - 0.41 9.9 3.7 0.49 9.6 2.6 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Iron_permease PF04120.7 KEG09465.1 - 0.53 9.8 3.9 0.67 9.5 2.7 1.1 1 0 0 1 1 1 0 Low affinity iron permease IncA PF04156.9 KEG09465.1 - 1.7 8.2 5.3 2.4 7.7 3.7 1.3 1 0 0 1 1 1 0 IncA protein PAP_assoc PF03828.14 KEG09466.1 - 2.4e-10 40.1 0.0 4.9e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase SPRY PF00622.23 KEG09467.1 - 0.025 14.6 0.0 0.04 14.0 0.0 1.3 1 0 0 1 1 1 0 SPRY domain Brucella_OMP2 PF05244.6 KEG09467.1 - 0.11 11.6 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 Brucella outer membrane protein 2 Ribosomal_S24e PF01282.14 KEG09468.1 - 1.9e-28 98.1 0.0 3.4e-28 97.2 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S24e Motile_Sperm PF00635.21 KEG09469.1 - 0.00038 20.0 0.0 0.038 13.6 0.0 3.9 5 0 0 5 5 5 1 MSP (Major sperm protein) domain DUF1034 PF06280.7 KEG09469.1 - 0.083 13.2 0.0 28 5.1 0.0 3.7 5 0 0 5 5 5 0 Fn3-like domain (DUF1034) Pox_RNA_pol PF03293.9 KEG09469.1 - 0.31 10.5 0.1 0.61 9.5 0.0 1.4 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit EPV_E5 PF08135.6 KEG09470.1 - 0.055 13.4 3.3 0.11 12.5 2.3 1.5 1 0 0 1 1 1 0 Major transforming protein E5 family KASH PF10541.4 KEG09470.1 - 0.11 12.3 2.7 0.23 11.3 1.9 1.5 1 0 0 1 1 1 0 Nuclear envelope localisation domain ThiC PF01964.13 KEG09471.1 - 0.17 10.3 1.2 0.25 9.7 0.9 1.2 1 0 0 1 1 1 0 ThiC family zf-met PF12874.2 KEG09474.1 - 1.5e-06 28.1 1.7 2.8e-06 27.3 1.2 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KEG09474.1 - 0.01 15.9 1.2 0.019 15.0 0.9 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding AKAP95 PF04988.7 KEG09474.1 - 0.044 13.5 0.6 0.06 13.1 0.4 1.2 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) DUF2090 PF09863.4 KEG09474.1 - 0.06 12.1 0.1 0.062 12.1 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2090) DUF2058 PF09831.4 KEG09474.1 - 1.5 8.6 6.3 2 8.2 4.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) AMP-binding PF00501.23 KEG09475.1 - 2.1e-29 102.1 0.0 8.7e-28 96.8 0.0 2.8 1 1 0 1 1 1 1 AMP-binding enzyme Inhibitor_I42 PF09394.5 KEG09477.1 - 1.2e-15 57.6 0.0 1.5e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Chagasin family peptidase inhibitor I42 Fucose_iso_C PF02952.12 KEG09477.1 - 0.11 11.9 0.1 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 L-fucose isomerase, C-terminal domain CGI-121 PF08617.5 KEG09478.1 - 9.9e-15 54.5 0.0 1.1e-14 54.4 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 SET PF00856.23 KEG09479.1 - 7.3e-08 32.8 0.0 4.7e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 SET domain SAF PF08666.7 KEG09479.1 - 0.027 14.8 0.0 1.1 9.7 0.0 2.3 2 0 0 2 2 2 0 SAF domain GFA PF04828.9 KEG09479.1 - 0.05 13.5 3.7 0.53 10.2 0.0 3.4 3 1 0 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme GCV_T PF01571.16 KEG09480.1 - 7.2e-17 61.4 0.0 1.3e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KEG09480.1 - 3.5e-07 30.1 0.0 7.3e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Serglycin PF04360.7 KEG09480.1 - 0.0028 17.4 0.1 0.0041 16.8 0.1 1.2 1 0 0 1 1 1 1 Serglycin DUF3740 PF12548.3 KEG09480.1 - 0.25 11.6 2.2 1.5 9.1 0.0 2.1 1 1 1 2 2 2 0 Sulfatase protein Herpes_capsid PF06112.6 KEG09480.1 - 0.81 9.7 7.3 1.2 9.1 5.1 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Porin_3 PF01459.17 KEG09481.1 - 0.018 14.3 0.7 0.37 10.0 0.5 2.6 1 1 0 1 1 1 0 Eukaryotic porin Pollen_Ole_e_I PF01190.12 KEG09481.1 - 0.041 13.7 2.0 1.3 8.9 0.2 2.5 1 1 1 2 2 2 0 Pollen proteins Ole e I like eIF2_C PF09173.6 KEG09485.1 - 1.7e-29 101.7 0.2 3.1e-29 100.8 0.1 1.5 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.22 KEG09485.1 - 7.9e-17 61.3 0.0 1.2e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 KEG09485.1 - 6.1e-06 26.2 3.2 2.8e-05 24.1 0.4 2.6 3 0 0 3 3 3 1 Elongation factor Tu domain 2 RNA_pol_Rbc25 PF08292.7 KEG09486.1 - 2.7e-26 92.1 0.0 5.7e-26 91.1 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 KEG09486.1 - 6.7e-25 87.0 0.0 1e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Motile_Sperm PF00635.21 KEG09487.1 - 2.7e-14 52.7 1.7 5.1e-14 51.8 1.0 1.6 1 1 0 1 1 1 1 MSP (Major sperm protein) domain DUF2116 PF09889.4 KEG09487.1 - 0.014 15.2 0.1 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Glycophorin_A PF01102.13 KEG09487.1 - 0.083 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A LCAT PF02450.10 KEG09488.1 - 3.1e-51 174.5 0.0 5.4e-49 167.1 0.0 2.1 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.2 KEG09488.1 - 0.0018 18.2 0.2 0.0036 17.2 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEG09488.1 - 0.026 14.2 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family TMF_DNA_bd PF12329.3 KEG09489.1 - 0.0041 16.8 5.2 0.006 16.3 1.5 2.3 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding EzrA PF06160.7 KEG09489.1 - 0.0043 15.3 2.2 0.0074 14.5 1.5 1.3 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA IFT57 PF10498.4 KEG09489.1 - 0.0045 15.7 4.5 0.0065 15.2 3.1 1.2 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 bZIP_1 PF00170.16 KEG09489.1 - 0.0061 16.4 1.4 0.0061 16.4 1.0 2.4 2 1 0 2 2 2 1 bZIP transcription factor Cast PF10174.4 KEG09489.1 - 0.0068 14.5 10.3 0.011 13.8 7.1 1.3 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone HALZ PF02183.13 KEG09489.1 - 0.028 14.1 1.6 0.094 12.4 1.1 1.9 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF342 PF03961.8 KEG09489.1 - 0.077 11.3 1.1 0.11 10.9 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) HAUS6_N PF14661.1 KEG09489.1 - 0.085 12.2 7.4 0.18 11.0 5.1 1.6 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus GAS PF13851.1 KEG09489.1 - 0.11 11.7 8.0 0.45 9.6 5.5 1.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ATP-synt_D PF01813.12 KEG09489.1 - 0.13 11.8 3.9 0.23 10.9 2.0 1.7 1 1 1 2 2 2 0 ATP synthase subunit D DivIC PF04977.10 KEG09489.1 - 0.13 11.7 6.4 0.071 12.6 2.3 2.0 1 1 0 1 1 1 0 Septum formation initiator OmpH PF03938.9 KEG09489.1 - 0.26 11.2 10.9 0.52 10.2 7.6 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) V_ATPase_I PF01496.14 KEG09489.1 - 0.3 8.8 0.6 0.4 8.4 0.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 KEG09489.1 - 0.43 9.5 5.7 0.77 8.7 4.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4407 PF14362.1 KEG09489.1 - 0.49 9.3 15.4 0.6 9.0 9.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) TMF_TATA_bd PF12325.3 KEG09489.1 - 1.3 8.7 9.4 0.12 12.1 1.5 2.6 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding IncA PF04156.9 KEG09489.1 - 2.2 7.8 11.6 1.5 8.4 5.8 1.9 2 0 0 2 2 2 0 IncA protein GrpE PF01025.14 KEG09489.1 - 6.2 6.3 8.8 7.2 6.1 4.6 2.2 2 1 0 2 2 2 0 GrpE DMPK_coil PF08826.5 KEG09489.1 - 6.3 6.7 11.3 17 5.4 0.1 2.9 2 1 1 3 3 3 0 DMPK coiled coil domain like ADIP PF11559.3 KEG09489.1 - 8.4 6.2 18.7 1.2 9.0 9.3 2.0 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding CDC50 PF03381.10 KEG09490.1 - 3.3e-72 242.9 0.0 6.2e-72 242.0 0.0 1.4 1 1 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family IncA PF04156.9 KEG09490.1 - 0.014 14.9 0.0 0.78 9.3 0.0 2.1 2 0 0 2 2 2 0 IncA protein Gag_spuma PF03276.9 KEG09491.1 - 0.1 10.9 1.6 0.12 10.6 1.1 1.2 1 0 0 1 1 1 0 Spumavirus gag protein DUF2839 PF10999.3 KEG09492.1 - 0.13 12.2 2.1 2.5 8.1 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2839) zf-B_box PF00643.19 KEG09494.1 - 2.2e-08 33.8 1.1 4.6e-08 32.8 0.8 1.6 1 0 0 1 1 1 1 B-box zinc finger Myosin_tail_1 PF01576.14 KEG09494.1 - 0.0013 16.6 2.6 0.0018 16.1 1.8 1.1 1 0 0 1 1 1 1 Myosin tail TPR_MLP1_2 PF07926.7 KEG09494.1 - 0.041 13.6 5.1 0.073 12.8 3.5 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein AAA_13 PF13166.1 KEG09494.1 - 0.054 11.9 0.4 0.076 11.4 0.3 1.1 1 0 0 1 1 1 0 AAA domain PH_11 PF15413.1 KEG09494.1 - 0.13 12.5 0.9 0.34 11.1 0.6 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Laminin_II PF06009.7 KEG09494.1 - 0.15 11.8 5.4 1.5 8.5 3.8 2.1 1 1 1 2 2 2 0 Laminin Domain II DUF3584 PF12128.3 KEG09494.1 - 0.2 8.9 6.9 0.28 8.4 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DASH_Duo1 PF08651.5 KEG09494.1 - 1 8.9 6.3 3.1 7.4 0.7 2.5 1 1 1 2 2 2 0 DASH complex subunit Duo1 Lipase_3 PF01764.20 KEG09495.1 - 7.9e-16 57.9 0.0 1.3e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KEG09495.1 - 0.026 14.2 0.8 0.05 13.3 0.1 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family MBOAT PF03062.14 KEG09498.1 - 2.1e-05 23.8 5.0 2.2e-05 23.7 2.2 1.8 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family DUF2306 PF10067.4 KEG09498.1 - 0.013 15.6 0.5 0.034 14.2 0.3 1.8 1 0 0 1 1 1 0 Predicted membrane protein (DUF2306) PTS_EIIC_2 PF13303.1 KEG09498.1 - 2.4 6.9 11.6 0.26 10.0 3.3 2.0 2 0 0 2 2 2 0 Phosphotransferase system, EIIC PAP2 PF01569.16 KEG09499.1 - 5.6e-24 84.2 0.3 5.6e-24 84.2 0.2 2.1 1 1 0 2 2 2 1 PAP2 superfamily Lebercilin PF15619.1 KEG09501.1 - 0.017 14.5 1.6 0.017 14.5 1.1 2.3 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Jnk-SapK_ap_N PF09744.4 KEG09501.1 - 0.025 14.5 0.9 0.044 13.7 0.6 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Mnd1 PF03962.10 KEG09501.1 - 0.15 11.7 5.0 0.075 12.6 1.8 1.7 2 0 0 2 2 2 0 Mnd1 family Filament PF00038.16 KEG09501.1 - 0.35 10.3 7.5 0.34 10.3 4.6 1.6 1 1 0 1 1 1 0 Intermediate filament protein Atg14 PF10186.4 KEG09501.1 - 0.73 8.7 6.7 1.1 8.0 4.7 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Fez1 PF06818.10 KEG09501.1 - 1.1 9.3 10.9 0.28 11.1 5.1 1.7 2 0 0 2 2 2 0 Fez1 DUF4140 PF13600.1 KEG09501.1 - 2 8.9 9.9 2.1 8.8 5.0 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Cation_efflux PF01545.16 KEG09503.1 - 3.1e-34 118.3 8.0 1.2e-33 116.4 5.6 1.8 1 1 0 1 1 1 1 Cation efflux family Zip PF02535.17 KEG09503.1 - 0.34 9.8 18.5 0.24 10.3 7.0 2.4 1 1 0 2 2 2 0 ZIP Zinc transporter DUF2946 PF11162.3 KEG09503.1 - 9.1 6.5 10.6 0.35 11.0 2.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) TBP PF00352.16 KEG09504.1 - 1.7e-37 126.6 0.0 1.1e-17 63.1 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) TPR_8 PF13181.1 KEG09505.1 - 1.1e-05 24.8 2.0 0.00085 18.9 0.0 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 KEG09505.1 - 6.4e-05 22.8 0.7 0.5 10.6 0.0 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 KEG09505.1 - 6.9e-05 22.2 6.1 0.0069 15.9 0.1 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 KEG09505.1 - 9.7e-05 22.2 1.6 0.017 15.0 0.1 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEG09505.1 - 0.00022 21.7 3.9 0.29 11.8 0.2 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEG09505.1 - 0.00037 20.1 13.3 0.0044 16.8 0.1 4.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 KEG09505.1 - 0.0013 18.3 3.3 0.56 9.8 0.1 3.9 3 1 1 4 4 4 1 TPR repeat TPR_14 PF13428.1 KEG09505.1 - 0.005 17.3 3.0 3.1 8.6 0.1 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEG09505.1 - 0.019 15.2 3.4 4.3 7.7 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 KEG09505.1 - 0.035 14.2 3.5 2.1 8.5 0.0 3.1 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 OSCP PF00213.13 KEG09505.1 - 0.045 13.6 0.2 0.066 13.0 0.1 1.3 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit MIT PF04212.13 KEG09505.1 - 0.081 12.8 3.1 1.9 8.4 0.0 3.5 2 2 1 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 KEG09505.1 - 0.31 11.5 1.6 2.7 8.6 0.1 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat Sel1 PF08238.7 KEG09505.1 - 0.36 11.5 2.9 8.2 7.2 0.1 3.3 3 1 0 3 3 2 0 Sel1 repeat Lipase_3 PF01764.20 KEG09506.1 - 1.7e-23 82.7 0.1 4.2e-23 81.5 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KEG09506.1 - 0.0069 16.1 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KEG09506.1 - 0.0081 15.7 0.0 0.031 13.8 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KEG09506.1 - 0.046 13.6 0.1 0.096 12.5 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF676 PF05057.9 KEG09506.1 - 0.065 12.5 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) GCC2_GCC3 PF07699.8 KEG09507.1 - 0.19 11.3 2.5 0.36 10.4 1.8 1.4 1 0 0 1 1 1 0 GCC2 and GCC3 CECR6_TMEM121 PF14997.1 KEG09514.1 - 1.3e-07 31.4 5.8 1.1e-05 25.1 0.3 2.6 3 0 0 3 3 3 2 CECR6/TMEM121 family SicP-binding PF09119.5 KEG09515.1 - 0.088 12.5 0.0 14 5.4 0.0 2.6 2 0 0 2 2 2 0 SicP binding FGase PF05013.7 KEG09516.1 - 0.0084 16.0 1.4 0.63 9.8 0.1 2.5 2 0 0 2 2 2 2 N-formylglutamate amidohydrolase Choline_kinase PF01633.15 KEG09518.1 - 4.3e-31 108.1 0.0 1.4e-30 106.5 0.0 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 KEG09518.1 - 5.1e-12 46.0 1.7 4.7e-09 36.3 0.1 3.1 3 1 0 3 3 3 2 Phosphotransferase enzyme family HA2 PF04408.18 KEG09519.1 - 1.5e-25 89.1 0.3 1e-24 86.4 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KEG09519.1 - 4.9e-18 65.0 0.0 9.8e-18 64.0 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KEG09519.1 - 7e-15 54.6 0.0 1.7e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEG09519.1 - 3e-08 33.3 0.3 3.2e-07 29.9 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KEG09519.1 - 1.1e-05 25.5 0.0 3.5e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KEG09519.1 - 0.00068 18.6 0.0 0.0015 17.4 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 KEG09519.1 - 0.011 15.6 0.1 5.9 6.6 0.0 2.9 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit ABC_tran PF00005.22 KEG09519.1 - 0.024 14.9 0.1 0.51 10.6 0.0 2.4 1 1 0 1 1 1 0 ABC transporter SRP54 PF00448.17 KEG09519.1 - 0.03 13.7 0.0 0.078 12.4 0.0 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Sigma54_activ_2 PF14532.1 KEG09519.1 - 0.035 14.1 0.0 0.56 10.2 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_29 PF13555.1 KEG09519.1 - 0.055 12.9 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.1 KEG09519.1 - 0.11 12.2 0.1 0.71 9.6 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain AAA_30 PF13604.1 KEG09519.1 - 0.13 11.7 0.0 0.31 10.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain INCENP_ARK-bind PF03941.10 KEG09519.1 - 0.48 10.2 0.0 0.48 10.2 0.0 2.0 2 0 0 2 2 1 0 Inner centromere protein, ARK binding region Armet PF10208.4 KEG09520.1 - 2e-07 30.7 0.1 5.2e-07 29.4 0.0 1.7 2 0 0 2 2 2 1 Degradation arginine-rich protein for mis-folding SAP PF02037.22 KEG09520.1 - 0.0018 17.7 0.0 0.006 16.0 0.0 1.9 2 0 0 2 2 2 1 SAP domain Gemini_C4 PF01492.12 KEG09521.1 - 0.58 9.9 6.6 4.1 7.2 1.1 3.0 1 1 1 2 2 2 0 Geminivirus C4 protein MBOAT PF03062.14 KEG09522.1 - 1.5e-19 70.3 8.8 1.5e-19 70.3 6.1 2.3 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT PF03062.14 KEG09524.1 - 8.1e-35 120.4 22.8 1.8e-34 119.3 15.5 1.9 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family UPF0154 PF03672.8 KEG09524.1 - 3 7.5 4.0 4.9 6.8 0.0 2.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) MBOAT PF03062.14 KEG09525.1 - 1.7e-35 122.6 20.4 1.7e-35 122.6 14.1 2.1 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Pkinase PF00069.20 KEG09527.1 - 8.2e-23 80.8 0.0 4.3e-08 32.6 0.0 4.3 4 1 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 KEG09527.1 - 4.3e-11 42.3 0.0 0.035 13.1 0.0 4.2 4 0 0 4 4 4 3 Protein tyrosine kinase Tom37_C PF11801.3 KEG09528.1 - 0.0016 18.3 0.6 0.0019 18.0 0.4 1.1 1 0 0 1 1 1 1 Tom37 C-terminal domain Na_H_Exchanger PF00999.16 KEG09529.1 - 4.3e-16 58.4 26.2 4.3e-16 58.4 18.2 1.8 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family DUF1129 PF06570.6 KEG09529.1 - 6.7 5.9 12.6 2.2 7.5 0.2 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1129) QRPTase_C PF01729.14 KEG09530.1 - 0.17 11.3 0.2 0.22 11.0 0.1 1.1 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Metal_resist PF13801.1 KEG09533.1 - 0.0027 17.7 10.7 0.0027 17.7 7.4 3.6 3 1 0 3 3 3 1 Heavy-metal resistance Takusan PF04822.8 KEG09533.1 - 0.024 14.3 0.0 0.024 14.3 0.0 2.9 3 1 0 3 3 3 0 Takusan Kinesin-relat_1 PF12711.2 KEG09533.1 - 0.043 14.2 1.7 0.043 14.2 1.2 3.4 2 1 0 2 2 2 0 Kinesin motor Seryl_tRNA_N PF02403.17 KEG09533.1 - 0.046 13.7 19.8 0.087 12.8 2.4 2.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4509 PF14970.1 KEG09533.1 - 1.6 8.3 9.1 0.32 10.6 2.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4509) DUF2959 PF11172.3 KEG09533.1 - 3.9 7.1 12.2 0.93 9.2 1.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2959) MCR_gamma PF02240.11 KEG09534.1 - 0.076 12.1 0.3 0.5 9.4 0.0 2.0 2 0 0 2 2 2 0 Methyl-coenzyme M reductase gamma subunit Methyltransf_16 PF10294.4 KEG09535.1 - 1.8e-09 37.2 0.0 1.3e-07 31.2 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 KEG09535.1 - 3.9e-06 26.3 0.0 5.8e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 KEG09535.1 - 0.00055 20.4 0.0 0.0013 19.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEG09535.1 - 0.0071 16.7 0.0 0.034 14.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEG09535.1 - 0.039 14.3 0.0 0.13 12.6 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KEG09535.1 - 0.042 13.4 0.0 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Abhydrolase_6 PF12697.2 KEG09537.1 - 6.8e-25 88.2 0.3 9.5e-25 87.8 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEG09537.1 - 1.7e-10 40.8 0.0 4e-10 39.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 KEG09537.1 - 2.1e-05 23.7 0.0 0.00042 19.5 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.15 KEG09537.1 - 0.00057 19.5 0.0 0.0087 15.6 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.8 KEG09537.1 - 0.0012 18.5 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.3 KEG09537.1 - 0.01 15.6 0.0 0.2 11.5 0.0 2.7 2 1 0 2 2 2 0 Putative lysophospholipase Ser_hydrolase PF06821.8 KEG09537.1 - 0.013 15.0 0.3 0.021 14.4 0.2 1.3 1 0 0 1 1 1 0 Serine hydrolase FSH1 PF03959.8 KEG09537.1 - 0.03 13.7 0.0 5 6.4 0.0 2.7 2 1 1 3 3 3 0 Serine hydrolase (FSH1) DUF676 PF05057.9 KEG09537.1 - 0.054 12.7 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) 4HBT_3 PF13622.1 KEG09538.1 - 3.7e-06 26.8 0.7 4.7e-06 26.5 0.1 1.6 2 0 0 2 2 2 1 Thioesterase-like superfamily 4HBT PF03061.17 KEG09538.1 - 2.9e-05 24.0 0.0 6.7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily VacA2 PF03077.9 KEG09538.1 - 0.0038 16.7 2.3 0.0075 15.8 1.6 1.5 1 0 0 1 1 1 1 Putative vacuolating cytotoxin RRM_1 PF00076.17 KEG09539.1 - 7.3e-17 60.7 0.0 9.9e-17 60.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG09539.1 - 2.9e-13 49.5 0.0 4e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG09539.1 - 3.1e-11 42.9 0.0 4.7e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pex14_N PF04695.8 KEG09539.1 - 0.35 10.8 2.7 0.56 10.2 1.9 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region GST_N_3 PF13417.1 KEG09540.1 - 8.1e-05 22.7 0.1 0.00028 21.0 0.1 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 KEG09540.1 - 0.00011 22.0 0.1 0.00044 20.1 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin GST_C_3 PF14497.1 KEG09540.1 - 0.022 15.2 0.0 0.044 14.2 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KEG09540.1 - 0.047 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain RRM_1 PF00076.17 KEG09542.1 - 1.3e-15 56.7 0.1 4.2e-15 55.1 0.1 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG09542.1 - 4.2e-12 45.8 0.0 7.4e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG09542.1 - 3.7e-06 26.7 0.1 5.3e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med15 PF09606.5 KEG09542.1 - 0.028 12.6 35.0 0.034 12.3 24.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2076 PF09849.4 KEG09542.1 - 0.11 12.5 23.2 0.15 12.0 16.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) CPSF100_C PF13299.1 KEG09542.1 - 0.22 11.6 4.1 0.53 10.4 2.8 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal PAT1 PF09770.4 KEG09542.1 - 0.67 8.1 28.2 0.77 7.9 19.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.11 KEG09542.1 - 0.88 9.4 3.1 0.88 9.4 2.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CMV_1a PF12467.3 KEG09542.1 - 0.89 9.8 8.1 2.3 8.5 5.6 1.7 1 1 0 1 1 1 0 Cucumber mosaic virus 1a protein family DUF4407 PF14362.1 KEG09542.1 - 6.2 5.6 7.9 9.6 5.0 5.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) adh_short PF00106.20 KEG09544.1 - 1.8e-18 67.0 1.6 1.8e-18 67.0 1.1 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KEG09544.1 - 2.7e-09 36.9 0.7 4.9e-09 36.0 0.5 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KEG09544.1 - 4.5e-06 26.8 0.2 7.9e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KEG09544.1 - 8.5e-05 22.0 0.1 0.00013 21.4 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 KEG09544.1 - 0.018 14.1 0.1 0.037 13.1 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short_C2 PF13561.1 KEG09544.1 - 0.03 14.0 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 KEG09544.1 - 0.034 13.7 0.4 0.053 13.1 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 KEG09544.1 - 0.035 14.3 0.2 0.086 13.0 0.1 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox PF00070.22 KEG09544.1 - 0.09 13.2 0.2 0.19 12.1 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase THF_DHG_CYH_C PF02882.14 KEG09544.1 - 0.091 11.8 0.0 0.19 10.7 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Dmrt1 PF12374.3 KEG09544.1 - 0.42 11.0 2.6 0.73 10.2 0.7 2.1 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 adh_short PF00106.20 KEG09545.1 - 3.1e-17 62.9 0.0 6.2e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEG09545.1 - 7e-08 32.3 0.0 1.4e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEG09545.1 - 9.4e-07 28.8 0.0 1.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KEG09545.1 - 1.9e-05 24.2 0.0 3.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEG09545.1 - 0.0082 16.1 0.0 0.26 11.2 0.0 2.4 1 1 0 1 1 1 1 NADH(P)-binding Abhydrolase_2 PF02230.11 KEG09547.1 - 1.6e-42 145.3 0.0 2.1e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KEG09547.1 - 7.4e-13 48.4 0.1 1.1e-12 47.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEG09547.1 - 1.2e-09 38.3 0.7 0.00015 21.7 0.7 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEG09547.1 - 4.4e-05 22.8 0.0 0.025 13.7 0.0 2.8 2 1 1 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_4 PF08386.5 KEG09547.1 - 0.0088 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein DLH PF01738.13 KEG09547.1 - 0.013 14.8 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Cutinase PF01083.17 KEG09547.1 - 0.13 11.9 0.3 0.25 11.0 0.2 1.5 1 1 0 1 1 1 0 Cutinase Abhydro_lipase PF04083.11 KEG09547.1 - 0.16 11.3 0.3 1.1 8.6 0.2 2.3 2 1 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region ThiF PF00899.16 KEG09550.1 - 1.8e-49 167.0 3.3 6.9e-31 106.8 0.1 2.4 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 KEG09550.1 - 3.8e-30 103.2 0.0 1e-21 76.2 0.0 2.9 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 KEG09550.1 - 9.6e-25 87.1 0.0 2e-24 86.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 KEG09550.1 - 1.5e-20 72.3 2.6 2.6e-20 71.5 0.8 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 KEG09550.1 - 0.019 15.0 2.8 3.2 7.8 0.7 3.1 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Lactamase_B PF00753.22 KEG09551.1 - 1.3e-14 54.3 0.8 1.2e-08 34.7 0.1 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KEG09551.1 - 0.01 15.4 0.2 0.018 14.6 0.1 1.6 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Beta-Casp PF10996.3 KEG09551.1 - 0.12 12.2 0.0 17 5.3 0.0 2.4 2 0 0 2 2 2 0 Beta-Casp domain Kelch_5 PF13854.1 KEG09552.1 - 9e-12 44.6 1.7 0.0054 16.6 0.0 4.1 3 0 0 3 3 3 3 Kelch motif Kelch_4 PF13418.1 KEG09552.1 - 7.3e-09 35.2 10.1 0.00015 21.4 0.0 5.1 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.10 KEG09552.1 - 6.8e-05 22.4 0.4 0.066 13.0 0.0 4.6 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 KEG09552.1 - 0.0003 20.8 15.8 0.0013 18.8 0.0 6.5 7 0 0 7 7 7 1 Galactose oxidase, central domain Kelch_6 PF13964.1 KEG09552.1 - 0.00086 19.3 4.1 8.3 6.7 0.0 4.8 5 0 0 5 5 5 2 Kelch motif Mito_carr PF00153.22 KEG09554.1 - 1.1e-08 34.6 0.1 9.5e-08 31.6 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial carrier protein Carn_acyltransf PF00755.15 KEG09557.1 - 9.2e-137 456.6 0.0 1.1e-136 456.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase SEP PF08059.8 KEG09558.1 - 3.1e-11 43.4 0.0 5.7e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 SEP domain DUF667 PF05018.8 KEG09561.1 - 6.3e-99 328.8 0.1 7.7e-99 328.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) DUF4140 PF13600.1 KEG09561.1 - 0.019 15.4 0.0 0.031 14.7 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) RPAP2_Rtr1 PF04181.8 KEG09562.1 - 2.7e-13 49.8 0.0 4.5e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family CCDC92 PF14916.1 KEG09563.1 - 0.0063 16.0 2.6 0.0063 16.0 1.8 3.1 2 1 1 3 3 3 1 Coiled-coil domain of unknown function DUF2623 PF11115.3 KEG09563.1 - 0.029 14.2 0.0 0.34 10.8 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2623) RNA_pol_Rpc34 PF05158.7 KEG09563.1 - 0.098 11.8 1.6 0.13 11.3 1.0 1.4 1 1 0 1 1 1 0 RNA polymerase Rpc34 subunit APC_CDC26 PF10471.4 KEG09563.1 - 0.12 13.1 0.6 0.12 13.1 0.4 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 Phage_int_SAM_4 PF13495.1 KEG09563.1 - 0.77 10.1 6.2 1.6 9.0 1.4 2.6 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain Suf PF05843.9 KEG09563.1 - 1.7 8.2 6.8 2.4 7.7 4.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF1280 PF06918.9 KEG09563.1 - 5.4 6.1 7.9 2.8 7.0 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1280) DUF607 PF04678.8 KEG09564.1 - 1.3e-24 87.1 0.6 1.8e-24 86.6 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF607 Peptidase_M16 PF00675.15 KEG09565.1 - 2e-12 47.1 0.0 4.8e-12 45.8 0.0 1.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KEG09565.1 - 0.00058 19.5 0.0 0.0025 17.5 0.0 2.1 1 1 0 1 1 1 1 Peptidase M16 inactive domain DUF4618 PF15397.1 KEG09565.1 - 0.17 11.2 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Vps51 PF08700.6 KEG09566.1 - 7.4e-26 89.8 3.9 2.4e-24 84.9 1.1 3.1 3 0 0 3 3 3 1 Vps51/Vps67 Sec5 PF15469.1 KEG09566.1 - 4.8e-11 42.7 0.2 1.5e-10 41.1 0.1 1.8 1 0 0 1 1 1 1 Exocyst complex component Sec5 COG2 PF06148.6 KEG09566.1 - 1.6e-07 31.2 2.4 1.6e-07 31.2 1.7 2.1 2 0 0 2 2 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Dor1 PF04124.7 KEG09566.1 - 1.7e-07 30.0 1.2 3.4e-07 29.0 0.9 1.5 1 0 0 1 1 1 1 Dor1-like family Vps53_N PF04100.7 KEG09566.1 - 8.5e-07 28.0 1.5 1.7e-06 27.1 1.1 1.4 1 0 0 1 1 1 1 Vps53-like, N-terminal COG5 PF10392.4 KEG09566.1 - 1.3e-06 28.3 2.3 1.3e-06 28.3 1.6 2.2 3 0 0 3 3 2 1 Golgi transport complex subunit 5 DUF2450 PF10475.4 KEG09566.1 - 9.8e-06 24.6 3.6 1.9e-05 23.7 2.5 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Zw10 PF06248.8 KEG09566.1 - 0.0013 17.0 1.3 0.0022 16.2 0.9 1.3 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 DUF1664 PF07889.7 KEG09566.1 - 0.0044 16.8 0.5 0.015 15.1 0.3 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.1 KEG09566.1 - 0.0084 16.3 1.2 0.52 10.6 0.6 2.8 2 1 0 2 2 2 1 Snapin/Pallidin BLOC1_2 PF10046.4 KEG09566.1 - 0.0093 16.0 0.6 0.038 14.1 0.4 2.1 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.7 KEG09566.1 - 0.011 15.4 6.3 0.025 14.3 1.2 3.0 3 0 0 3 3 3 0 Laminin Domain II NPV_P10 PF05531.7 KEG09566.1 - 0.012 15.8 1.0 0.07 13.3 0.3 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.4 KEG09566.1 - 0.12 12.2 2.2 0.32 10.8 1.5 1.7 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlgN PF05130.7 KEG09566.1 - 0.18 12.0 4.1 0.14 12.3 1.1 2.2 2 0 0 2 2 1 0 FlgN protein Baculo_PEP_C PF04513.7 KEG09566.1 - 1.4 8.7 6.0 0.87 9.4 0.3 3.4 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-U1 PF06220.7 KEG09567.1 - 1.4e-06 27.7 1.3 3.5e-06 26.4 0.3 2.1 2 0 0 2 2 2 1 U1 zinc finger Mito_carr PF00153.22 KEG09569.1 - 1.8e-50 168.6 7.2 1.2e-22 79.4 0.3 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein UAA PF08449.6 KEG09571.1 - 3.7e-07 29.3 26.7 8.1e-07 28.2 18.5 1.4 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 KEG09571.1 - 8.5e-06 25.4 10.7 8.5e-06 25.4 7.4 3.1 2 2 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 KEG09571.1 - 2.3e-05 24.4 29.5 0.001 19.1 10.2 2.8 2 2 0 2 2 2 2 EamA-like transporter family DNA_pol_A_exo1 PF01612.15 KEG09572.1 - 1.4e-39 135.3 0.2 2.4e-39 134.6 0.1 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 KEG09572.1 - 3.4e-22 78.5 0.0 1.1e-21 76.9 0.0 1.9 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.18 KEG09572.1 - 6.6e-09 35.3 0.0 2.8e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 HRDC domain PSI PF01437.20 KEG09573.1 - 0.017 15.2 3.1 0.017 15.2 2.1 2.4 2 0 0 2 2 2 0 Plexin repeat PIP5K PF01504.13 KEG09574.1 - 2.1e-68 230.1 0.0 2.9e-68 229.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cyt-b5 PF00173.23 KEG09576.1 - 5.4e-07 29.3 0.0 8.2e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BRE1 PF08647.6 KEG09577.1 - 0.72 9.8 17.3 0.025 14.5 3.9 3.3 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase ACR_tran PF00873.14 KEG09577.1 - 2.6 5.3 3.4 4 4.7 2.4 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Pkinase PF00069.20 KEG09578.1 - 3.7e-49 167.2 0.0 8.8e-49 165.9 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG09578.1 - 2e-18 66.3 0.1 1.4e-17 63.6 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KEG09578.1 - 4.5e-05 23.2 0.9 0.019 14.6 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family PIP49_C PF12260.3 KEG09578.1 - 0.0077 15.6 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Choline_kinase PF01633.15 KEG09578.1 - 0.018 14.6 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase PP2C PF00481.16 KEG09579.1 - 4.2e-64 216.3 0.0 4.2e-64 216.3 0.0 2.0 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.7 KEG09579.1 - 1e-05 25.3 0.2 0.064 12.9 0.0 2.6 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 KEG09579.1 - 3.5e-05 23.3 0.0 8.5e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C VIT1 PF01988.14 KEG09579.1 - 0.19 11.1 1.5 0.33 10.3 1.0 1.4 1 0 0 1 1 1 0 VIT family Adeno_E4_34 PF04528.8 KEG09579.1 - 0.57 9.7 2.4 18 4.9 0.9 2.7 2 0 0 2 2 2 0 Adenovirus early E4 34 kDa protein conserved region DUF4220 PF13968.1 KEG09579.1 - 2.5 7.1 4.3 4.4 6.2 3.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) WD40 PF00400.27 KEG09580.1 - 5.6e-09 35.5 8.3 0.0014 18.4 0.0 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF2415 PF10313.4 KEG09580.1 - 0.025 14.2 0.2 1.3 8.7 0.0 2.9 3 0 0 3 3 3 0 Uncharacterised protein domain (DUF2415) DEAD PF00270.24 KEG09581.1 - 2.1e-36 124.9 0.4 4.3e-35 120.6 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEG09581.1 - 1.2e-20 73.0 0.6 4.3e-20 71.3 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEG09581.1 - 1e-06 28.6 0.0 2.6e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 KEG09581.1 - 0.0002 20.5 2.5 0.00042 19.4 0.0 2.6 4 0 0 4 4 4 1 U3-containing 90S pre-ribosomal complex subunit PEP_mutase PF13714.1 KEG09581.1 - 0.046 12.9 0.3 0.24 10.6 0.0 2.2 3 0 0 3 3 3 0 Phosphoenolpyruvate phosphomutase Choline_transpo PF04515.7 KEG09583.1 - 4e-79 265.7 43.9 4e-79 265.7 30.4 2.4 3 0 0 3 3 3 1 Plasma-membrane choline transporter LETM1 PF07766.8 KEG09584.1 - 7.4e-07 28.4 0.0 2.6e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 LETM1-like protein PAS_11 PF14598.1 KEG09584.1 - 0.0072 16.2 2.3 0.063 13.2 0.0 2.9 3 0 0 3 3 3 1 PAS domain GST_C_2 PF13410.1 KEG09585.1 - 0.00012 21.9 0.0 0.00031 20.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pkinase PF00069.20 KEG09589.1 - 8.6e-42 143.0 0.0 3.5e-41 141.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG09589.1 - 2e-19 69.6 0.0 3.3e-13 49.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KEG09589.1 - 0.0019 17.2 0.0 0.0041 16.1 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KEG09589.1 - 0.053 13.2 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family SR-25 PF10500.4 KEG09590.1 - 0.47 9.8 3.5 0.76 9.1 2.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CRCB PF02537.10 KEG09593.1 - 2.8e-34 117.4 22.0 7e-19 67.8 2.7 2.5 3 0 0 3 3 3 2 CrcB-like protein Phage_holin_3 PF05106.7 KEG09593.1 - 0.27 11.2 2.2 1.3 9.0 0.0 2.8 2 1 1 3 3 3 0 Phage holin family (Lysis protein S) RNA_pol_Rpb1_1 PF04997.7 KEG09594.1 - 5.1e-100 335.0 0.3 9.4e-100 334.1 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 KEG09594.1 - 6.9e-100 333.8 0.1 1.3e-99 332.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KEG09594.1 - 4.5e-65 218.6 0.5 1.6e-64 216.8 0.1 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 KEG09594.1 - 2.5e-43 147.9 0.8 5.3e-43 146.9 0.6 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 KEG09594.1 - 1.3e-41 141.9 0.0 3.4e-41 140.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 KEG09594.1 - 4.8e-27 94.3 1.0 4.8e-27 94.3 0.7 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 KEG09594.1 - 5.2e-26 90.4 0.1 1.3e-25 89.2 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 PspA_IM30 PF04012.7 KEG09594.1 - 0.11 11.8 3.2 0.23 10.7 2.2 1.4 1 0 0 1 1 1 0 PspA/IM30 family DUF294_C PF10335.4 KEG09595.1 - 0.067 12.8 8.9 0.65 9.6 1.6 2.7 2 0 0 2 2 2 0 Putative nucleotidyltransferase substrate binding domain Phage_GP20 PF06810.6 KEG09595.1 - 0.31 10.4 1.8 0.55 9.6 0.3 2.0 2 0 0 2 2 2 0 Phage minor structural protein GP20 Phage_Mu_Gam PF07352.7 KEG09595.1 - 0.44 10.0 3.6 1.3 8.5 2.1 2.1 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein Calreticulin PF00262.13 KEG09596.1 - 3.2e-121 404.4 23.4 1.2e-102 343.2 10.9 2.1 1 1 1 2 2 2 2 Calreticulin family TerD PF02342.13 KEG09597.1 - 5.1e-22 78.0 0.0 6.2e-22 77.8 0.0 1.0 1 0 0 1 1 1 1 TerD domain DUF3949 PF13133.1 KEG09597.1 - 0.11 12.7 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3949) Adenylsucc_synt PF00709.16 KEG09598.1 - 3e-108 362.2 0.0 3.7e-108 361.9 0.0 1.1 1 0 0 1 1 1 1 Adenylosuccinate synthetase EphA2_TM PF14575.1 KEG09599.1 - 0.037 14.4 1.2 0.07 13.5 0.8 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 KEG09599.1 - 0.14 11.8 0.1 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family Neur_chan_memb PF02932.11 KEG09599.1 - 0.51 10.1 5.8 2.3 8.0 4.0 2.1 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Laminin_G_1 PF00054.18 KEG09599.1 - 1 9.4 7.5 4.4 7.3 0.2 3.2 1 1 2 3 3 3 0 Laminin G domain Ribosomal_L27 PF01016.14 KEG09600.1 - 0.16 11.8 0.1 0.37 10.6 0.0 1.7 2 0 0 2 2 2 0 Ribosomal L27 protein Nucleoside_tran PF01733.13 KEG09601.1 - 3.3e-27 95.4 6.5 3.3e-27 95.4 4.5 1.6 2 0 0 2 2 2 1 Nucleoside transporter Ribosomal_S4e PF00900.15 KEG09602.1 - 5.2e-26 90.1 0.5 9.1e-26 89.3 0.4 1.4 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 KEG09602.1 - 4.8e-18 64.7 2.4 1.2e-17 63.4 1.7 1.8 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 KEG09602.1 - 1.1e-08 34.3 0.0 2.6e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 KEG09602.1 - 3.4e-06 26.5 0.4 2e-05 24.0 0.1 2.5 2 0 0 2 2 2 1 KOW motif TPK_B1_binding PF04265.9 KEG09603.1 - 4.2e-14 52.0 0.9 1e-13 50.7 0.0 2.1 3 0 0 3 3 3 1 Thiamin pyrophosphokinase, vitamin B1 binding domain TPK_catalytic PF04263.11 KEG09603.1 - 4.2e-08 32.7 0.0 0.0039 16.7 0.0 3.1 3 0 0 3 3 3 2 Thiamin pyrophosphokinase, catalytic domain Claudin_3 PF06653.6 KEG09604.1 - 0.007 16.1 0.4 0.022 14.5 0.0 1.7 2 0 0 2 2 2 1 Tight junction protein, Claudin-like DUF3357 PF11837.3 KEG09604.1 - 0.024 14.4 0.1 0.077 12.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) P12 PF12669.2 KEG09604.1 - 0.054 13.6 0.2 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 Virus attachment protein p12 family EphA2_TM PF14575.1 KEG09604.1 - 0.063 13.6 0.4 0.21 12.0 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TrbL PF04610.9 KEG09604.1 - 0.15 11.7 3.6 0.24 11.0 2.5 1.3 1 1 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein DUF2749 PF10907.3 KEG09604.1 - 0.46 10.3 2.4 0.63 9.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) Apolipoprotein PF01442.13 KEG09605.1 - 0.0014 18.1 8.6 0.0014 18.1 6.0 4.3 2 1 1 3 3 3 2 Apolipoprotein A1/A4/E domain MtrG PF04210.8 KEG09605.1 - 0.26 10.9 5.1 19 5.0 0.3 4.2 3 1 1 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, subunit G Baculo_PEP_C PF04513.7 KEG09605.1 - 2 8.2 18.8 0.12 12.1 0.1 4.9 4 1 2 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus AMPKBI PF04739.10 KEG09607.1 - 3.3e-18 65.4 0.0 5.8e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interation domain Steroid_dh PF02544.11 KEG09610.1 - 8.2e-37 126.2 0.7 1.7e-36 125.2 0.5 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 KEG09610.1 - 2.1e-06 27.2 0.4 4.4e-06 26.1 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 KEG09610.1 - 0.067 13.2 0.5 0.067 13.2 0.4 2.8 2 1 1 3 3 3 0 Phospholipid methyltransferase SET PF00856.23 KEG09612.1 - 4.4e-14 53.1 0.0 1e-12 48.6 0.0 2.1 1 1 0 1 1 1 1 SET domain FtsJ PF01728.14 KEG09613.1 - 2.9e-47 161.0 0.2 3.4e-47 160.7 0.2 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 KEG09613.1 - 1e-05 25.2 0.0 2.2e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain NSP13 PF06460.7 KEG09613.1 - 0.0019 17.1 0.0 0.0034 16.3 0.0 1.5 1 1 0 1 1 1 1 Coronavirus NSP13 Methyltransf_31 PF13847.1 KEG09613.1 - 0.0051 16.4 0.0 0.0072 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEG09613.1 - 0.023 14.6 0.2 0.052 13.5 0.1 1.5 1 1 0 1 1 1 0 Methyltransferase domain cNMP_binding PF00027.24 KEG09615.1 - 0.00022 20.9 0.0 0.0017 18.1 0.0 2.2 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain Secretin_N PF03958.12 KEG09616.1 - 0.039 14.1 0.3 20 5.4 0.0 3.7 3 0 0 3 3 3 0 Bacterial type II/III secretion system short domain TF_Zn_Ribbon PF08271.7 KEG09617.1 - 0.00043 19.5 0.6 0.00043 19.5 0.4 2.0 2 0 0 2 2 2 1 TFIIB zinc-binding Lar_restr_allev PF14354.1 KEG09617.1 - 0.016 15.5 0.2 0.039 14.2 0.1 1.7 1 0 0 1 1 1 0 Restriction alleviation protein Lar TFIIB PF00382.14 KEG09617.1 - 0.045 13.5 0.1 0.15 11.8 0.1 1.8 1 0 0 1 1 1 0 Transcription factor TFIIB repeat DUF2387 PF09526.5 KEG09617.1 - 0.058 13.3 0.2 0.15 11.9 0.2 1.7 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) Ribosomal_60s PF00428.14 KEG09617.1 - 3.3 8.1 13.7 8.2 6.9 4.2 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein ubiquitin PF00240.18 KEG09619.1 - 0.0016 17.8 0.0 0.018 14.3 0.0 2.5 3 0 0 3 3 3 1 Ubiquitin family Pox_A_type_inc PF04508.7 KEG09619.1 - 0.054 13.3 1.2 0.12 12.2 0.1 2.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat CENP-F_leu_zip PF10473.4 KEG09619.1 - 0.097 12.5 0.2 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lipase_3 PF01764.20 KEG09621.1 - 1.1e-18 67.2 0.0 3e-18 65.8 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 KEG09621.1 - 0.00044 19.9 0.0 0.00074 19.1 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KEG09621.1 - 0.0025 17.7 1.9 0.0033 17.3 0.1 2.1 2 2 0 2 2 2 1 Alpha/beta hydrolase family Lipase PF00151.14 KEG09621.1 - 0.0031 16.7 0.0 0.0048 16.1 0.0 1.2 1 0 0 1 1 1 1 Lipase Abhydrolase_5 PF12695.2 KEG09621.1 - 0.0041 16.8 0.0 0.0081 15.9 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 KEG09621.1 - 0.015 14.6 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.15 KEG09621.1 - 0.036 13.6 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold SET PF00856.23 KEG09622.1 - 5.3e-06 26.8 0.0 6.7e-05 23.2 0.0 2.1 1 1 0 1 1 1 1 SET domain Inhibitor_I69 PF13734.1 KEG09623.1 - 0.05 13.7 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Spi protease inhibitor DUF948 PF06103.6 KEG09625.1 - 0.73 9.7 5.7 0.4 10.5 0.6 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) UPF0020 PF01170.13 KEG09626.1 - 2.1e-21 76.3 0.0 1.8e-09 37.4 0.0 2.4 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 KEG09626.1 - 3.2e-10 40.0 0.0 1.3e-09 38.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEG09626.1 - 0.0061 17.0 0.0 0.027 14.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain THUMP PF02926.12 KEG09626.1 - 0.02 14.8 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 THUMP domain N6_N4_Mtase PF01555.13 KEG09626.1 - 0.24 10.8 0.0 0.46 9.9 0.0 1.3 1 0 0 1 1 1 0 DNA methylase Hydrolase_6 PF13344.1 KEG09627.1 - 0.024 14.5 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase R3H-assoc PF13902.1 KEG09630.1 - 5.1e-23 81.4 0.2 1.1e-22 80.3 0.2 1.6 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.17 KEG09630.1 - 0.00035 20.1 0.4 0.0078 15.8 0.0 2.8 2 1 1 3 3 3 1 R3H domain LRR_8 PF13855.1 KEG09631.1 - 8.1e-05 22.2 0.1 0.35 10.6 0.0 3.7 2 1 2 4 4 4 3 Leucine rich repeat LRR_7 PF13504.1 KEG09631.1 - 0.00092 19.0 3.2 23 5.7 0.0 5.9 6 0 0 6 6 6 1 Leucine rich repeat HSCB_C PF07743.8 KEG09631.1 - 0.017 15.5 1.8 0.065 13.6 1.2 2.0 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain LRR_6 PF13516.1 KEG09631.1 - 0.035 14.1 0.8 36 4.8 0.0 4.6 4 0 0 4 4 4 0 Leucine Rich repeat Spore_YhcN_YlaJ PF09580.5 KEG09632.1 - 0.042 13.9 0.1 0.042 13.9 0.1 2.9 2 1 1 3 3 3 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DSPc PF00782.15 KEG09633.1 - 5.4e-13 48.6 0.2 5.8e-12 45.3 0.1 2.1 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KEG09633.1 - 0.0019 17.5 0.2 0.0029 16.9 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Phage_ASH PF10554.4 KEG09634.1 - 0.11 12.8 0.1 0.15 12.3 0.1 1.5 1 1 0 1 1 1 0 Ash protein family DER1 PF04511.10 KEG09635.1 - 2.5e-31 108.7 1.7 3e-31 108.4 1.2 1.0 1 0 0 1 1 1 1 Der1-like family DUF485 PF04341.7 KEG09635.1 - 0.031 13.9 0.7 0.11 12.2 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function, DUF485 Pkinase PF00069.20 KEG09636.1 - 2.4e-56 190.7 0.0 3.7e-56 190.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG09636.1 - 8e-38 129.9 0.0 1.8e-35 122.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KEG09636.1 - 0.00049 19.1 0.0 0.0012 17.8 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEG09636.1 - 0.09 12.4 0.0 0.31 10.7 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Cache_1 PF02743.13 KEG09636.1 - 0.099 12.2 0.0 0.36 10.4 0.0 1.9 1 0 0 1 1 1 0 Cache domain zf-MYND PF01753.13 KEG09637.1 - 3.3e-07 30.0 12.4 7.7e-07 28.8 8.6 1.7 1 0 0 1 1 1 1 MYND finger CRA_rpt PF07046.6 KEG09638.1 - 1.1e-30 105.3 699.6 7.8e-05 22.5 24.1 28.5 2 1 27 29 29 29 16 Cytoplasmic repetitive antigen (CRA) like repeat Piwi PF02171.12 KEG09639.1 - 1.4e-14 53.7 0.0 3.1e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 KEG09639.1 - 8.6e-08 31.5 0.1 1.9e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 PAZ domain PSI PF01437.20 KEG09640.1 - 0.012 15.7 15.0 0.012 15.7 10.4 4.3 3 2 0 3 3 3 0 Plexin repeat zf-RING_5 PF14634.1 KEG09641.1 - 8.1e-05 22.2 2.6 0.0046 16.6 0.0 3.2 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KEG09641.1 - 0.00059 19.4 5.9 0.11 12.1 0.2 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEG09641.1 - 0.0018 18.2 6.2 0.0046 16.9 0.2 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEG09641.1 - 0.0081 15.8 7.0 0.012 15.2 1.1 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEG09641.1 - 0.015 15.1 5.1 0.043 13.6 0.4 3.0 3 0 0 3 3 3 0 Ring finger domain Osmo_MPGsynth PF09488.5 KEG09641.1 - 0.066 11.8 0.0 0.098 11.3 0.0 1.2 1 0 0 1 1 1 0 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) DiS_P_DiS PF06750.8 KEG09641.1 - 0.26 11.0 2.1 5.9 6.7 0.2 2.3 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain Elf1 PF05129.8 KEG09641.1 - 0.92 9.2 4.6 0.78 9.4 0.2 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Mpv17_PMP22 PF04117.7 KEG09642.1 - 2e-15 56.1 0.9 2e-15 56.1 0.6 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family ABC2_membrane_3 PF12698.2 KEG09643.1 - 8.8e-57 192.6 44.0 1e-37 129.9 9.8 2.8 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.22 KEG09643.1 - 4.6e-54 182.4 0.0 1.6e-26 93.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KEG09643.1 - 2.5e-15 57.2 0.0 0.00011 22.3 0.0 4.3 3 1 0 4 4 4 2 AAA domain AAA_23 PF13476.1 KEG09643.1 - 5.7e-05 23.5 0.5 0.077 13.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KEG09643.1 - 5.9e-05 22.4 0.0 0.3 10.2 0.0 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KEG09643.1 - 0.00011 21.4 0.0 1.4 7.8 0.0 3.5 4 0 0 4 4 4 1 AAA ATPase domain SbcCD_C PF13558.1 KEG09643.1 - 0.00022 21.0 1.8 0.23 11.3 0.0 3.6 3 2 0 3 3 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 KEG09643.1 - 0.00039 19.8 0.5 0.29 10.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 KEG09643.1 - 0.0014 17.8 0.0 0.11 11.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SRP54 PF00448.17 KEG09643.1 - 0.0029 17.0 1.7 1.4 8.3 0.1 2.2 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_25 PF13481.1 KEG09643.1 - 0.017 14.5 0.0 1.8 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KEG09643.1 - 0.022 14.1 0.0 2.7 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain UPF0079 PF02367.12 KEG09643.1 - 0.061 12.9 0.1 8.8 5.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 KEG09643.1 - 0.066 12.7 0.1 6.1 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KEG09643.1 - 0.088 12.5 0.1 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain Miro PF08477.8 KEG09643.1 - 0.099 13.1 0.0 16 6.0 0.0 2.9 3 0 0 3 3 2 0 Miro-like protein AAA PF00004.24 KEG09643.1 - 0.15 12.2 0.1 21 5.3 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 KEG09643.1 - 0.16 11.4 0.5 3.8 6.9 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_13 PF13166.1 KEG09643.1 - 0.16 10.3 0.2 2.5 6.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 KEG09643.1 - 0.58 9.9 2.8 1.7 8.4 0.1 2.6 3 0 0 3 3 2 0 Domain of unknown function DUF87 DUF1489 PF07370.6 KEG09644.1 - 0.069 12.6 0.0 0.081 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1489) APC_CDC26 PF10471.4 KEG09645.1 - 0.0028 18.3 0.2 1.1 10.0 0.0 2.1 2 0 0 2 2 2 2 Anaphase-promoting complex APC subunit 1 Pap_E4 PF02711.9 KEG09649.1 - 0.4 11.5 0.0 0.4 11.5 0.0 3.0 4 0 0 4 4 4 0 E4 protein Ada3 PF10198.4 KEG09650.1 - 0.0094 15.7 0.6 0.027 14.2 0.4 1.7 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 Pol_alpha_B_N PF08418.5 KEG09650.1 - 1.3 8.5 5.4 0.51 9.8 0.6 2.2 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal AAA PF00004.24 KEG09651.1 - 4.3e-39 133.7 0.8 1.1e-38 132.3 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KEG09651.1 - 4.9e-06 26.3 0.6 6.7e-05 22.6 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KEG09651.1 - 5.9e-05 23.1 3.7 0.017 15.1 0.0 3.2 2 2 1 3 3 3 2 AAA ATPase domain AAA_2 PF07724.9 KEG09651.1 - 0.00023 21.1 0.0 0.0015 18.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KEG09651.1 - 0.00062 18.8 0.1 0.0025 16.9 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Bacillus_HBL PF05791.6 KEG09651.1 - 0.00082 18.7 2.0 0.0023 17.3 1.4 1.7 2 0 0 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) DUF815 PF05673.8 KEG09651.1 - 0.0027 16.6 0.0 0.0066 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.1 KEG09651.1 - 0.0046 17.1 3.7 0.033 14.3 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KEG09651.1 - 0.0072 16.0 0.1 0.019 14.6 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 KEG09651.1 - 0.0073 15.4 0.0 0.018 14.1 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 KEG09651.1 - 0.0086 15.9 2.7 0.032 14.0 0.0 2.8 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 KEG09651.1 - 0.014 14.4 0.8 0.029 13.4 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin IstB_IS21 PF01695.12 KEG09651.1 - 0.015 14.7 0.1 0.049 13.0 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein CPT PF07931.7 KEG09651.1 - 0.018 14.6 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein KaiC PF06745.8 KEG09651.1 - 0.02 14.0 1.4 0.16 11.0 0.0 2.7 4 0 0 4 4 4 0 KaiC AAA_25 PF13481.1 KEG09651.1 - 0.025 14.0 0.2 0.025 14.0 0.2 2.3 2 1 1 3 3 3 0 AAA domain NACHT PF05729.7 KEG09651.1 - 0.032 13.9 0.1 0.65 9.6 0.0 2.4 1 1 1 2 2 2 0 NACHT domain AAA_3 PF07726.6 KEG09651.1 - 0.033 13.8 0.0 0.099 12.2 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 KEG09651.1 - 0.041 13.1 0.5 0.22 10.7 0.0 2.3 3 0 0 3 3 3 0 PhoH-like protein AAA_17 PF13207.1 KEG09651.1 - 0.047 14.5 3.3 0.059 14.2 0.1 2.6 2 2 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KEG09651.1 - 0.054 13.6 0.0 0.24 11.6 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Sigma54_activat PF00158.21 KEG09651.1 - 0.075 12.4 0.0 0.46 9.9 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.1 KEG09651.1 - 0.086 12.8 0.5 0.2 11.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain IncA PF04156.9 KEG09651.1 - 0.11 12.1 3.9 0.19 11.3 2.7 1.4 1 0 0 1 1 1 0 IncA protein MRG PF05712.8 KEG09651.1 - 0.18 10.6 2.6 0.19 10.5 1.0 1.6 2 0 0 2 2 2 0 MRG Atg14 PF10186.4 KEG09651.1 - 0.25 10.2 6.6 0.39 9.5 4.6 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 AAA_18 PF13238.1 KEG09651.1 - 0.46 10.7 4.2 1.7 8.9 0.1 2.8 2 2 0 2 2 2 0 AAA domain APG6 PF04111.7 KEG09651.1 - 0.71 8.8 5.2 1.1 8.2 3.6 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.8 KEG09651.1 - 4.2 7.7 7.2 18 5.7 3.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 KEG09652.1 - 0.00053 19.6 7.3 0.00053 19.6 5.1 4.9 1 1 2 3 3 3 1 IncA protein DUF2321 PF10083.4 KEG09652.1 - 0.011 15.2 1.2 0.033 13.6 0.8 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) Reo_sigmaC PF04582.7 KEG09652.1 - 0.12 11.4 8.3 0.3 10.2 0.1 2.8 1 1 1 3 3 3 0 Reovirus sigma C capsid protein DZR PF12773.2 KEG09652.1 - 0.18 11.6 6.1 0.36 10.6 4.2 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-RanBP PF00641.13 KEG09652.1 - 0.79 8.8 7.4 1.6 7.8 5.1 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others HA2 PF04408.18 KEG09655.1 - 1e-14 54.3 1.5 2.9e-14 52.9 0.0 2.5 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KEG09655.1 - 7e-12 45.0 0.0 1.9e-11 43.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEG09655.1 - 7.2e-09 35.3 0.1 8.6e-08 31.8 0.1 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase dsrm PF00035.20 KEG09655.1 - 1.2e-05 25.8 3.6 0.0032 18.0 0.0 4.0 4 0 0 4 4 4 1 Double-stranded RNA binding motif OB_NTP_bind PF07717.11 KEG09655.1 - 6e-05 22.8 0.0 0.00023 20.9 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 KEG09655.1 - 0.00051 20.1 0.0 0.0017 18.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KEG09655.1 - 0.0067 15.3 0.0 0.012 14.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.11 KEG09655.1 - 0.019 14.1 0.3 0.37 9.9 0.0 2.8 3 0 0 3 3 3 0 PhoH-like protein NB-ARC PF00931.17 KEG09655.1 - 0.028 13.2 0.0 0.049 12.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain KaiC PF06745.8 KEG09655.1 - 0.04 13.0 0.0 0.076 12.1 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.1 KEG09655.1 - 0.11 12.4 0.0 3.3 7.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain DUF2448 PF10476.4 KEG09656.1 - 0.00092 18.7 0.1 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2448) DUF1461 PF07314.6 KEG09656.1 - 0.015 15.0 0.2 0.018 14.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) Tropomyosin PF00261.15 KEG09657.1 - 0.0067 15.5 0.0 0.0085 15.2 0.0 1.2 1 0 0 1 1 1 1 Tropomyosin Kelch_3 PF13415.1 KEG09658.1 - 6.8e-15 54.7 0.2 1.1e-06 28.6 0.0 5.0 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.1 KEG09658.1 - 9.6e-15 54.1 8.7 8.4e-06 25.6 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 KEG09658.1 - 3.8e-14 52.1 1.1 2.3e-06 27.2 0.0 5.2 4 1 1 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.10 KEG09658.1 - 1.8e-13 49.6 2.0 8.6e-08 31.6 0.0 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 KEG09658.1 - 4.6e-10 38.8 0.6 2.3e-05 23.8 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 KEG09658.1 - 3.5e-09 36.4 2.3 0.00064 19.7 0.0 4.1 5 0 0 5 5 5 2 Kelch motif DUF3438 PF11920.3 KEG09660.1 - 0.012 14.4 0.5 0.024 13.4 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) XRN_N PF03159.13 KEG09662.1 - 0.0029 17.0 0.0 0.0067 15.8 0.0 1.6 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus DUF4061 PF13270.1 KEG09663.1 - 0.035 14.1 1.2 0.051 13.6 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) Hrs_helical PF12210.3 KEG09663.1 - 0.076 13.2 3.3 0.26 11.5 1.4 1.9 1 1 1 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Death PF00531.17 KEG09663.1 - 0.086 12.6 1.8 0.15 11.8 1.2 1.7 1 1 0 1 1 1 0 Death domain Peptidase_M19 PF01244.16 KEG09663.1 - 0.13 11.1 0.1 0.15 11.0 0.1 1.2 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) DUF4363 PF14276.1 KEG09663.1 - 0.14 11.8 0.3 0.22 11.2 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4363) HSCB_C PF07743.8 KEG09663.1 - 1.2 9.6 8.1 12 6.3 1.7 2.6 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain Chorein_N PF12624.2 KEG09664.1 - 0.0028 17.1 0.1 0.011 15.2 0.0 2.1 1 1 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter PMSR PF01625.16 KEG09665.1 - 1.7e-56 190.4 0.6 2.3e-56 190.0 0.4 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Nuc_deoxyrib_tr PF05014.10 KEG09665.1 - 0.013 15.3 0.2 0.022 14.6 0.0 1.4 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase TPR_19 PF14559.1 KEG09665.1 - 0.029 14.6 0.1 0.21 11.9 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEG09665.1 - 0.044 14.4 0.1 6.6 7.6 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat CCP_MauG PF03150.9 KEG09665.1 - 0.055 13.7 0.1 0.064 13.5 0.1 1.2 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase TPR_1 PF00515.23 KEG09665.1 - 0.065 12.8 2.0 0.31 10.7 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 KEG09665.1 - 0.092 13.4 0.1 1.9 9.2 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 KEG09665.1 - 0.26 11.2 2.0 3 7.9 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat EF-hand_7 PF13499.1 KEG09666.1 - 1.1e-05 25.4 0.0 4e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KEG09666.1 - 4e-05 22.6 0.0 0.00012 21.1 0.0 1.8 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 KEG09666.1 - 0.0093 15.7 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 KEG09666.1 - 0.011 15.0 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.1 KEG09666.1 - 0.038 13.6 0.0 0.087 12.4 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair Miro PF08477.8 KEG09666.1 - 0.048 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein UIM PF02809.15 KEG09667.1 - 2.4e-07 29.7 11.6 0.00034 19.9 3.4 3.1 2 0 0 2 2 2 2 Ubiquitin interaction motif DUF1537 PF07005.6 KEG09667.1 - 0.0057 16.3 0.0 0.0057 16.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF1537 CbiX PF01903.12 KEG09667.1 - 0.099 12.7 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 CbiX SynMuv_product PF06047.6 KEG09668.1 - 0.047 13.4 0.4 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Ras-induced vulval development antagonist Peptidase_C47 PF05543.8 KEG09668.1 - 0.096 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Staphopain peptidase C47 APG6 PF04111.7 KEG09668.1 - 0.3 10.0 5.7 0.13 11.2 1.3 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF848 PF05852.6 KEG09668.1 - 0.47 10.2 7.9 0.2 11.5 1.3 2.5 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) ADIP PF11559.3 KEG09668.1 - 0.5 10.2 7.8 4.3 7.2 0.5 2.6 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Carn_acyltransf PF00755.15 KEG09669.1 - 1.8e-55 188.1 0.0 5.3e-55 186.6 0.0 1.6 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase CHB_HEX_C PF03174.8 KEG09670.1 - 3.1e-21 74.9 0.7 2.3e-11 43.3 0.2 3.5 3 0 0 3 3 3 2 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.1 KEG09670.1 - 1.4e-19 69.9 0.6 7.6e-10 38.7 0.0 3.5 3 0 0 3 3 3 2 Fn3 associated CHB_HEX_C_1 PF13290.1 KEG09670.1 - 1.4e-18 66.4 1.2 1.4e-09 37.5 0.3 3.2 3 0 0 3 3 3 2 Chitobiase/beta-hexosaminidase C-terminal domain Ctr PF04145.10 KEG09671.1 - 0.19 11.7 1.7 0.23 11.4 0.2 1.8 2 0 0 2 2 2 0 Ctr copper transporter family APG6 PF04111.7 KEG09671.1 - 1.3 7.9 4.2 0.61 9.0 1.0 1.8 1 1 1 2 2 2 0 Autophagy protein Apg6 TPM PF04536.9 KEG09672.1 - 2.2e-14 53.3 0.0 3.5e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase Elf1 PF05129.8 KEG09672.1 - 6.7 6.4 8.0 3 7.5 3.0 2.2 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like DUF2387 PF09526.5 KEG09672.1 - 8.6 6.3 7.2 7.9 6.4 2.8 2.3 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) WD40 PF00400.27 KEG09673.1 - 5.9e-25 86.2 1.7 1.9e-05 24.3 0.0 6.1 5 1 0 5 5 5 5 WD domain, G-beta repeat Not3 PF04065.10 KEG09674.1 - 3.5e-59 199.9 13.8 5.3e-59 199.3 9.5 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component Dicty_REP PF05086.7 KEG09674.1 - 0.014 13.1 8.5 0.24 9.1 1.2 2.1 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein HrcA PF01628.16 KEG09674.1 - 0.095 12.2 1.2 0.23 11.0 0.8 1.6 1 0 0 1 1 1 0 HrcA protein C terminal domain Mucin PF01456.12 KEG09674.1 - 0.57 9.9 31.1 2 8.2 12.9 2.6 2 0 0 2 2 2 0 Mucin-like glycoprotein HoxA13_N PF12284.3 KEG09674.1 - 8 6.6 15.7 0.11 12.6 3.4 2.4 2 0 0 2 2 2 0 Hox protein A13 N terminal SLBP_RNA_bind PF15247.1 KEG09675.1 - 4e-23 80.9 3.3 4e-23 80.9 2.3 2.0 2 0 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain CDC45 PF02724.9 KEG09676.1 - 0.018 13.1 6.1 0.017 13.2 4.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.2 KEG09676.1 - 2.2 5.8 9.7 2.2 5.8 6.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nucleo_P87 PF07267.6 KEG09676.1 - 9.2 4.8 10.8 10 4.6 7.5 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RecA PF00154.16 KEG09677.1 - 1.1e-06 27.9 0.0 1.9e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.1 KEG09677.1 - 2.4e-06 27.1 1.6 4e-05 23.0 1.1 2.3 1 1 0 1 1 1 1 AAA domain Rad51 PF08423.6 KEG09677.1 - 0.00012 21.0 0.0 0.00046 19.1 0.0 1.8 2 0 0 2 2 2 1 Rad51 AAA_33 PF13671.1 KEG09677.1 - 0.0045 16.8 0.0 0.01 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KEG09677.1 - 0.018 14.1 0.0 0.032 13.3 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.1 KEG09677.1 - 0.46 10.2 0.1 0.46 10.2 0.0 3.3 4 0 0 4 4 4 0 Part of AAA domain UPF0104 PF03706.8 KEG09678.1 - 0.00036 19.9 4.2 0.00046 19.5 2.9 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0104) PIG-F PF06699.6 KEG09678.1 - 0.026 14.4 2.0 0.032 14.1 1.4 1.1 1 0 0 1 1 1 0 GPI biosynthesis protein family Pig-F RseC_MucC PF04246.7 KEG09678.1 - 0.18 11.3 1.6 3.7 7.1 0.0 2.0 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF3624 PF12292.3 KEG09678.1 - 4.5 7.7 5.4 1.4 9.3 1.1 2.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3624) Complex1_LYR_1 PF13232.1 KEG09679.1 - 9e-07 29.0 1.5 1.8e-06 28.0 1.0 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KEG09679.1 - 1.5e-06 27.8 1.1 2.7e-06 27.0 0.8 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) UPF0113 PF03657.8 KEG09680.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0113) SNARE PF05739.14 KEG09681.1 - 7.3e-19 67.2 2.8 7.3e-19 67.2 1.9 2.5 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 KEG09681.1 - 0.92 9.7 16.3 0.34 11.1 4.3 2.8 2 1 1 3 3 3 0 Syntaxin MalF_P2 PF14785.1 KEG09681.1 - 0.95 9.3 5.5 2.1 8.2 3.4 2.0 1 1 0 1 1 1 0 Maltose transport system permease protein MalF P2 domain Syntaxin-6_N PF09177.6 KEG09681.1 - 4.1 7.8 12.4 2.2 8.7 1.9 3.4 1 1 0 2 2 2 0 Syntaxin 6, N-terminal DZR PF12773.2 KEG09685.1 - 0.77 9.6 6.8 0.078 12.8 0.9 2.2 2 0 0 2 2 2 0 Double zinc ribbon Guanylate_cyc PF00211.15 KEG09687.1 - 3.6e-11 42.7 0.0 6.6e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Oxidored_q6 PF01058.17 KEG09688.1 - 4.5e-19 68.3 0.1 6.1e-19 67.9 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit NAD_binding_1 PF00175.16 KEG09689.1 - 2.9e-21 76.0 0.0 5.1e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KEG09689.1 - 2.7e-14 53.0 0.0 4.4e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KEG09689.1 - 9.5e-07 28.8 0.0 4.1e-05 23.5 0.0 2.2 1 1 1 2 2 2 1 Ferric reductase NAD binding domain UBA PF00627.26 KEG09690.1 - 9.4e-10 38.0 0.1 9.4e-10 38.0 0.1 2.6 3 0 0 3 3 3 1 UBA/TS-N domain ubiquitin PF00240.18 KEG09690.1 - 0.001 18.3 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family YadA_anchor PF03895.10 KEG09691.1 - 0.8 9.7 7.8 0.3 11.1 2.8 2.0 2 0 0 2 2 2 0 YadA-like C-terminal region Phg_2220_C PF09524.5 KEG09695.1 - 0.03 14.2 0.1 0.14 12.1 0.1 2.0 2 0 0 2 2 2 0 Conserved phage C-terminus (Phg_2220_C) Atg8 PF02991.11 KEG09696.1 - 1.8e-15 56.7 0.0 2.4e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like WND PF07861.6 KEG09696.1 - 0.036 13.0 0.2 0.046 12.7 0.1 1.1 1 0 0 1 1 1 0 WisP family N-Terminal Region APG12 PF04110.8 KEG09696.1 - 0.13 12.4 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-like autophagy protein Apg12 Hexapep PF00132.19 KEG09697.1 - 3.3e-05 23.1 1.0 0.014 14.8 0.0 4.0 3 1 1 5 5 5 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KEG09697.1 - 0.00096 18.6 0.1 0.075 12.6 0.0 2.9 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase PDZ_2 PF13180.1 KEG09700.1 - 5e-10 39.1 0.0 1.4e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 KEG09700.1 - 5.1e-06 26.5 0.0 1.9e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) EF-hand_like PF09279.6 KEG09700.1 - 0.0024 17.8 0.0 0.0053 16.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like PI-PLC-X PF00388.14 KEG09700.1 - 0.005 16.2 0.0 0.017 14.5 0.0 1.9 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Ribosomal_S30 PF04758.9 KEG09701.1 - 4.8e-28 96.6 8.8 5.5e-28 96.4 6.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 IP_trans PF02121.13 KEG09702.1 - 0.063 12.4 0.0 0.092 11.9 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol transfer protein CS PF04969.11 KEG09703.1 - 7.7e-19 68.0 0.4 1.1e-18 67.5 0.3 1.2 1 0 0 1 1 1 1 CS domain FTZ PF03867.9 KEG09704.1 - 0.2 10.8 3.7 0.3 10.2 2.6 1.2 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region TPR_11 PF13414.1 KEG09707.1 - 5.5e-26 90.0 18.8 1.8e-08 33.9 0.2 5.9 4 2 3 7 7 7 6 TPR repeat TPR_2 PF07719.12 KEG09707.1 - 3e-23 79.8 20.2 5.8e-06 25.8 0.1 8.7 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_16 PF13432.1 KEG09707.1 - 9.9e-20 70.6 9.9 0.00077 20.0 0.1 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 KEG09707.1 - 9.2e-19 66.1 13.4 1.1e-05 24.8 0.1 6.7 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.1 KEG09707.1 - 6.1e-17 61.3 18.5 0.00063 19.6 0.0 6.2 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 KEG09707.1 - 1.1e-14 53.0 10.6 0.00042 19.9 0.1 7.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 KEG09707.1 - 1.1e-14 52.9 5.3 0.015 15.0 0.0 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 KEG09707.1 - 3.2e-13 49.8 11.4 0.00093 19.4 0.0 6.5 4 2 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 KEG09707.1 - 1.1e-10 41.1 9.4 0.62 10.8 0.0 8.0 6 2 2 8 8 8 2 Tetratricopeptide repeat Apc3 PF12895.2 KEG09707.1 - 6.8e-09 35.7 23.8 0.0019 18.2 0.1 5.3 3 3 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 KEG09707.1 - 2.9e-08 33.2 6.8 0.55 10.5 0.0 7.1 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_15 PF13429.1 KEG09707.1 - 2.5e-06 26.7 5.1 0.26 10.3 0.1 4.6 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 KEG09707.1 - 3.9e-06 26.9 11.2 0.66 10.5 0.0 7.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 KEG09707.1 - 0.019 14.7 12.7 2.1 8.2 0.0 5.8 5 1 2 7 7 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KEG09707.1 - 0.022 14.6 4.1 8.7 6.3 0.0 5.1 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat DUF3856 PF12968.2 KEG09707.1 - 0.048 13.4 3.0 0.064 13.0 0.5 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_10 PF13374.1 KEG09707.1 - 0.053 13.4 15.1 21 5.2 0.0 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat IKI3 PF04762.7 KEG09707.1 - 0.31 8.8 0.8 0.45 8.2 0.5 1.1 1 0 0 1 1 1 0 IKI3 family Ribosomal_S6 PF01250.12 KEG09708.1 - 0.0024 17.7 0.5 0.0051 16.6 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S6 ASF1_hist_chap PF04729.8 KEG09709.1 - 2.2e-52 176.7 0.0 2.7e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone Tymo_coat PF00983.13 KEG09709.1 - 0.022 14.4 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 Tymovirus coat protein BRCA-2_OB1 PF09103.5 KEG09710.1 - 6.8e-34 116.0 0.0 1.2e-33 115.3 0.0 1.4 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA2 PF00634.13 KEG09710.1 - 0.011 14.9 0.0 0.024 13.8 0.0 1.6 1 0 0 1 1 1 0 BRCA2 repeat Nup54 PF13874.1 KEG09712.1 - 0.0064 16.1 9.5 0.0064 16.1 6.6 2.8 1 1 2 3 3 3 1 Nucleoporin complex subunit 54 Occludin_ELL PF07303.8 KEG09712.1 - 0.036 14.8 2.2 3.2 8.5 0.5 2.4 1 1 1 2 2 2 0 Occludin homology domain AAA_13 PF13166.1 KEG09712.1 - 0.04 12.3 3.2 0.042 12.3 2.2 1.1 1 0 0 1 1 1 0 AAA domain zf-C4H2 PF10146.4 KEG09712.1 - 0.046 13.7 6.5 0.02 14.9 2.7 1.6 1 1 0 1 1 1 0 Zinc finger-containing protein SecD-TM1 PF13721.1 KEG09712.1 - 0.11 12.7 1.3 0.18 12.0 0.1 1.9 1 1 1 2 2 2 0 SecD export protein N-terminal TM region DUF342 PF03961.8 KEG09712.1 - 0.12 10.7 1.1 0.16 10.3 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) MerB PF03243.10 KEG09712.1 - 0.16 11.8 1.9 0.2 11.4 0.6 1.6 2 0 0 2 2 2 0 Alkylmercury lyase V_ATPase_I PF01496.14 KEG09712.1 - 0.44 8.3 3.9 0.52 8.1 2.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tox-ODYAM1 PF15642.1 KEG09712.1 - 0.45 9.1 5.8 0.33 9.5 2.6 1.6 1 1 1 2 2 2 0 Toxin in Odyssella and Amoebophilus IFT57 PF10498.4 KEG09712.1 - 0.46 9.1 9.7 0.53 8.9 6.2 1.6 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 PhaP_Bmeg PF09602.5 KEG09712.1 - 0.56 10.0 8.9 2.4 7.9 2.2 2.7 1 1 1 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) APG6 PF04111.7 KEG09712.1 - 1.3 7.9 9.8 1.6 7.7 6.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3552 PF12072.3 KEG09712.1 - 1.7 7.8 22.1 0.3 10.2 11.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) HAUS6_N PF14661.1 KEG09712.1 - 2.2 7.5 17.0 2 7.7 10.8 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Atg14 PF10186.4 KEG09712.1 - 3.9 6.3 12.6 6 5.7 8.4 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ING PF12998.2 KEG09712.1 - 4.6 7.5 6.5 1.1e+02 3.1 4.5 2.4 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding DUF972 PF06156.8 KEG09712.1 - 8.9 6.7 7.3 31 4.9 5.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF972) ketoacyl-synt PF00109.21 KEG09715.1 - 0.078 12.4 0.5 0.088 12.2 0.3 1.0 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain PGK PF00162.14 KEG09716.1 - 2.2e-159 530.1 0.1 1.2e-152 507.9 0.0 2.0 2 0 0 2 2 2 2 Phosphoglycerate kinase PPR_3 PF13812.1 KEG09721.1 - 0.45 10.9 2.3 71 4.0 0.0 4.7 5 0 0 5 5 5 0 Pentatricopeptide repeat domain WD40 PF00400.27 KEG09722.1 - 5.1e-17 61.0 11.1 0.04 13.8 0.0 8.5 9 0 0 9 9 9 6 WD domain, G-beta repeat Reo_sigmaC PF04582.7 KEG09722.1 - 0.22 10.6 0.5 2.6 7.1 0.1 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DNA_pol_B PF00136.16 KEG09723.1 - 2.7e-123 412.2 0.0 5.1e-123 411.2 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KEG09723.1 - 1.4e-43 149.0 0.0 2.5e-43 148.2 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.5 KEG09723.1 - 9e-05 21.9 0.5 0.00083 18.7 0.6 2.2 2 0 0 2 2 2 1 DNA Polymerase alpha zinc finger ERO1 PF04137.10 KEG09724.1 - 5.5e-97 324.9 0.0 6.7e-97 324.6 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) CDP-OH_P_transf PF01066.16 KEG09725.1 - 1.8e-15 57.0 6.1 1.8e-15 57.0 4.2 3.2 2 2 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Gtr1_RagA PF04670.7 KEG09727.1 - 7.5e-65 218.3 0.0 9.5e-65 217.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KEG09727.1 - 1.8e-05 24.7 0.0 3.8e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KEG09727.1 - 7.8e-05 23.1 0.0 0.0029 18.0 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KEG09727.1 - 0.0002 20.6 0.0 0.0006 19.0 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.13 KEG09727.1 - 0.06 12.6 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B YliH PF10799.3 KEG09727.1 - 0.088 12.5 0.2 0.19 11.3 0.1 1.6 1 0 0 1 1 1 0 Biofilm formation protein (YliH/bssR) APH PF01636.18 KEG09731.1 - 6e-14 52.3 0.1 1.2e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family HAD_2 PF13419.1 KEG09731.1 - 0.0098 16.1 0.1 0.6 10.2 0.0 3.2 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase MORN PF02493.15 KEG09732.1 - 2.2e-05 23.8 4.9 0.012 15.3 0.0 4.8 6 0 0 6 6 6 2 MORN repeat NHL PF01436.16 KEG09732.1 - 0.081 12.9 0.1 0.33 11.0 0.0 2.1 2 0 0 2 2 2 0 NHL repeat DUF1738 PF08401.6 KEG09733.1 - 0.013 15.1 0.0 0.069 12.8 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1738) MFS_1 PF07690.11 KEG09735.1 - 4.3e-20 71.7 26.6 1.9e-14 53.1 13.5 3.2 1 1 1 3 3 3 3 Major Facilitator Superfamily Nodulin-like PF06813.8 KEG09735.1 - 2.7e-07 30.0 19.6 2.7e-07 30.0 13.6 2.6 2 1 0 2 2 2 1 Nodulin-like DUF3040 PF11239.3 KEG09735.1 - 0.17 11.9 4.8 1.8 8.7 0.0 4.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3040) Ribosomal_L11_N PF03946.9 KEG09736.1 - 0.092 12.2 0.4 0.22 10.9 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein L11, N-terminal domain SAGA-Tad1 PF12767.2 KEG09736.1 - 7.7 6.1 13.5 0.053 13.1 1.3 2.5 2 1 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit PP2C PF00481.16 KEG09737.1 - 1.3e-29 103.4 0.1 3.6e-26 92.0 0.0 2.5 2 0 0 2 2 2 2 Protein phosphatase 2C Pkinase PF00069.20 KEG09738.1 - 4.8e-70 235.6 0.0 6.2e-70 235.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG09738.1 - 1.9e-35 122.2 0.0 2.7e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FYVE PF01363.16 KEG09738.1 - 3.4e-11 42.8 11.6 3.4e-11 42.8 8.1 2.4 2 0 0 2 2 2 1 FYVE zinc finger PH PF00169.24 KEG09738.1 - 1.9e-07 31.2 0.0 4e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 PH domain Kinase-like PF14531.1 KEG09738.1 - 0.00012 21.1 0.0 0.0002 20.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KEG09738.1 - 0.0011 18.0 0.0 0.0017 17.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zinc_ribbon_4 PF13717.1 KEG09738.1 - 0.069 12.8 0.2 0.069 12.8 0.1 2.8 3 1 1 4 4 4 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 KEG09738.1 - 0.085 12.4 0.2 0.085 12.4 0.1 2.7 3 1 2 5 5 4 0 zinc-ribbon domain Cript PF10235.4 KEG09738.1 - 0.24 11.7 5.0 0.59 10.5 2.2 2.5 3 0 0 3 3 3 0 Microtubule-associated protein CRIPT DZR PF12773.2 KEG09738.1 - 2 8.3 18.9 1.8e+02 2.0 13.2 3.1 1 1 1 2 2 2 0 Double zinc ribbon Ly-6_related PF06579.7 KEG09745.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Caenorhabditis elegans ly-6-related protein CLAMP PF14769.1 KEG09749.1 - 0.0018 18.3 0.0 0.21 11.7 0.0 2.3 2 0 0 2 2 2 2 Flagellar C1a complex subunit C1a-32 Mistic PF11458.3 KEG09749.1 - 0.12 12.7 1.4 0.34 11.3 0.3 2.1 2 0 0 2 2 2 0 Membrane-integrating protein Mistic DUF3110 PF11360.3 KEG09750.1 - 0.083 12.7 0.0 2.6 7.9 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3110) FHA PF00498.21 KEG09751.1 - 7.3e-15 54.8 0.0 1.6e-14 53.7 0.0 1.6 1 1 0 1 1 1 1 FHA domain ADK PF00406.17 KEG09755.1 - 7.1e-25 87.6 0.0 8.2e-25 87.4 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 KEG09755.1 - 7e-14 51.1 0.0 1.3e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 KEG09755.1 - 3.1e-07 31.2 0.0 5.1e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KEG09755.1 - 6.8e-05 22.7 0.0 0.00015 21.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KEG09755.1 - 9.6e-05 22.6 0.0 0.00029 21.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KEG09755.1 - 0.0002 21.1 0.0 0.00061 19.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KEG09755.1 - 0.0037 16.9 0.4 0.015 15.0 0.1 2.2 2 1 0 2 2 2 1 Part of AAA domain RuvB_N PF05496.7 KEG09755.1 - 0.0041 16.2 0.0 0.0078 15.2 0.0 1.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 KEG09755.1 - 0.0092 15.9 0.0 0.019 14.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KEG09755.1 - 0.015 14.3 0.0 0.039 13.0 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.24 KEG09755.1 - 0.019 15.1 0.0 0.029 14.5 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP-sulfurylase PF01747.12 KEG09755.1 - 0.038 13.3 0.0 0.095 12.0 0.0 1.6 2 0 0 2 2 2 0 ATP-sulfurylase AAA_16 PF13191.1 KEG09755.1 - 0.044 13.7 0.1 0.085 12.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 KEG09755.1 - 0.044 13.9 0.0 0.088 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Cytidylate_kin2 PF13189.1 KEG09755.1 - 0.048 13.5 0.0 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase-like family Sigma54_activ_2 PF14532.1 KEG09755.1 - 0.052 13.5 0.0 0.18 11.8 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain Thymidylate_kin PF02223.12 KEG09755.1 - 0.072 12.4 0.0 1 8.6 0.0 2.3 3 0 0 3 3 3 0 Thymidylate kinase Ldh_1_C PF02866.13 KEG09756.1 - 5.7e-17 61.9 0.0 2.1e-08 34.1 0.0 2.2 2 0 0 2 2 2 2 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 KEG09756.1 - 1.8e-14 53.7 0.0 2.8e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_N PF00056.18 KEG09757.1 - 6.1e-45 152.5 0.0 8.6e-45 152.0 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KEG09757.1 - 2.6e-42 144.4 0.0 3.7e-42 144.0 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain DapB_N PF01113.15 KEG09757.1 - 0.0062 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.14 KEG09757.1 - 0.012 14.3 0.0 0.017 13.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Lycopene_cycl PF05834.7 KEG09758.1 - 0.15 10.9 0.2 0.17 10.7 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Glyco_hydro_38 PF01074.17 KEG09759.1 - 2.1e-64 217.4 3.8 3e-64 216.9 2.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 KEG09759.1 - 1.8e-44 152.2 0.0 2.5e-44 151.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 KEG09759.1 - 9.6e-21 73.7 0.0 2.2e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Nop25 PF09805.4 KEG09760.1 - 9.6e-13 48.3 11.9 9.6e-13 48.3 8.2 3.0 2 1 1 3 3 3 1 Nucleolar protein 12 (25kDa) Methyltransf_26 PF13659.1 KEG09761.1 - 6.8e-08 32.5 0.0 2.6e-07 30.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEG09761.1 - 2.2e-05 24.1 0.0 0.0012 18.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEG09761.1 - 2.9e-05 24.6 0.1 9.1e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEG09761.1 - 0.0032 16.8 0.0 0.013 14.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KEG09761.1 - 0.0033 17.7 0.0 0.011 16.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEG09761.1 - 0.0062 16.9 0.0 0.041 14.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEG09761.1 - 0.0062 16.2 0.0 0.074 12.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEG09761.1 - 0.0067 16.8 0.0 0.019 15.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KEG09761.1 - 0.013 14.1 0.0 0.022 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.1 KEG09761.1 - 0.078 12.6 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 KEG09761.1 - 0.13 11.3 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) AviRa PF11599.3 KEG09761.1 - 0.16 10.9 0.0 0.31 10.0 0.0 1.4 1 0 0 1 1 1 0 RRNA methyltransferase AviRa DUF72 PF01904.13 KEG09763.1 - 2.7e-46 158.2 0.0 5.4e-43 147.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function DUF72 AP_endonuc_2 PF01261.19 KEG09763.1 - 0.054 12.7 0.0 0.088 12.0 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel EDR1 PF14381.1 KEG09764.1 - 4.7e-28 98.1 0.0 1.1e-27 97.0 0.0 1.6 1 1 0 1 1 1 1 Ethylene-responsive protein kinase Le-CTR1 Pkinase PF00069.20 KEG09764.1 - 2.9e-26 92.1 0.0 4.7e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG09764.1 - 1.7e-18 66.6 0.0 2.7e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase zf-PARP PF00645.13 KEG09765.1 - 3.8e-22 78.3 0.1 7e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-CCHH PF10283.4 KEG09765.1 - 7.3e-12 44.8 0.9 1.2e-11 44.1 0.6 1.4 1 0 0 1 1 1 1 Zinc-finger (CX5CX6HX5H) motif Metallophos PF00149.23 KEG09766.1 - 2.2e-27 95.7 0.0 5.9e-27 94.3 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Methyltransf_28 PF02636.12 KEG09766.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase ALG3 PF05208.8 KEG09767.1 - 4.1e-113 378.3 16.1 4.8e-113 378.1 11.2 1.0 1 0 0 1 1 1 1 ALG3 protein DUF4381 PF14316.1 KEG09767.1 - 0.013 15.5 0.1 0.013 15.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) WD40 PF00400.27 KEG09768.1 - 0.00016 21.4 11.7 1.4 8.9 0.0 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat dsrm PF00035.20 KEG09770.1 - 0.16 12.5 0.7 5.4 7.6 0.2 2.5 2 0 0 2 2 2 0 Double-stranded RNA binding motif PI3_PI4_kinase PF00454.22 KEG09771.1 - 1.9e-30 106.0 0.3 3.4e-29 101.9 0.2 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 KEG09771.1 - 1.9e-10 40.2 0.0 4.4e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) FWWh PF14922.1 KEG09772.1 - 4.3e-23 81.5 0.1 3.1e-20 72.2 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function Glyco_hydro_101 PF12905.2 KEG09773.1 - 0.04 12.5 1.4 0.055 12.0 1.0 1.1 1 0 0 1 1 1 0 Endo-alpha-N-acetylgalactosaminidase Ras PF00071.17 KEG09774.1 - 1e-27 96.5 0.0 4.8e-22 78.0 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KEG09774.1 - 5e-13 49.5 0.0 1.2e-11 45.0 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KEG09774.1 - 5.4e-07 29.0 0.0 9.6e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KEG09774.1 - 0.00054 19.9 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KEG09774.1 - 0.04 13.9 0.0 0.07 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.4 KEG09774.1 - 0.077 12.4 0.0 1.4 8.3 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 KEG09774.1 - 0.11 11.9 0.0 8.5 5.7 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KEG09774.1 - 0.11 11.6 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KEG09774.1 - 0.13 11.4 0.0 0.96 8.6 0.0 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KEG09774.1 - 0.29 9.7 0.0 0.29 9.7 0.0 3.2 3 2 1 4 4 4 0 G-protein alpha subunit BAT2_N PF07001.6 KEG09775.1 - 0.13 12.5 3.3 0.25 11.6 2.3 1.4 1 0 0 1 1 1 0 BAT2 N-terminus TROVE PF05731.6 KEG09779.1 - 2.2e-51 174.8 0.0 9.4e-29 100.3 0.0 2.2 1 1 1 2 2 2 2 TROVE domain WD40 PF00400.27 KEG09779.1 - 1.5e-32 110.2 22.4 6e-05 22.7 0.0 11.1 11 0 0 11 11 11 7 WD domain, G-beta repeat NACHT PF05729.7 KEG09779.1 - 4.5e-06 26.4 0.0 1.1e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 NACHT domain DUF4062 PF13271.1 KEG09779.1 - 0.0002 21.2 0.0 0.0019 18.2 0.0 2.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4062) AUX_IAA PF02309.11 KEG09779.1 - 0.083 12.6 0.4 0.16 11.6 0.0 1.6 2 0 0 2 2 2 0 AUX/IAA family Mito_fiss_reg PF05308.6 KEG09779.1 - 0.8 9.0 6.1 0.26 10.6 2.0 1.8 2 0 0 2 2 2 0 Mitochondrial fission regulator Adap_comp_sub PF00928.16 KEG09780.1 - 1.3e-60 204.7 0.0 1.6e-60 204.4 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KEG09780.1 - 0.013 15.2 0.3 0.025 14.2 0.2 1.5 1 0 0 1 1 1 0 Clathrin adaptor complex small chain ACBP PF00887.14 KEG09781.1 - 9.5e-20 70.0 0.8 1.1e-19 69.9 0.5 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein DUF4129 PF13559.1 KEG09781.1 - 0.077 12.9 0.1 0.33 10.9 0.0 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4129) TIP49 PF06068.8 KEG09782.1 - 2.2e-179 596.2 3.6 2.2e-179 596.2 2.5 1.7 2 0 0 2 2 2 1 TIP49 C-terminus AAA PF00004.24 KEG09782.1 - 6.3e-08 32.8 3.2 5e-05 23.5 0.1 3.3 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEG09782.1 - 1.4e-06 28.4 0.6 0.11 12.6 0.0 3.4 2 1 0 3 3 3 2 AAA domain RuvB_N PF05496.7 KEG09782.1 - 2.7e-06 26.6 1.5 0.0017 17.4 0.0 3.1 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KEG09782.1 - 8.5e-06 25.8 0.4 0.00051 20.0 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain DnaB_C PF03796.10 KEG09782.1 - 1e-05 24.5 0.1 1.9e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_5 PF07728.9 KEG09782.1 - 1.8e-05 24.4 0.3 0.0032 17.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KEG09782.1 - 0.00014 21.0 1.2 0.0021 17.2 0.3 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KEG09782.1 - 0.00035 20.2 0.4 0.0012 18.5 0.0 2.1 2 0 0 2 2 1 1 Part of AAA domain FtsK_SpoIIIE PF01580.13 KEG09782.1 - 0.00042 19.8 0.5 0.18 11.2 0.1 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_25 PF13481.1 KEG09782.1 - 0.0033 16.8 0.1 0.0079 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KEG09782.1 - 0.0036 16.4 0.4 0.01 14.9 0.3 1.7 1 0 0 1 1 1 1 Zeta toxin UPF0079 PF02367.12 KEG09782.1 - 0.0072 15.9 0.1 0.018 14.6 0.1 1.7 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 KaiC PF06745.8 KEG09782.1 - 0.0093 15.1 0.2 0.021 13.9 0.1 1.7 1 0 0 1 1 1 1 KaiC NACHT PF05729.7 KEG09782.1 - 0.02 14.5 0.0 0.042 13.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.21 KEG09782.1 - 0.025 14.0 0.0 6.9 6.1 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Zot PF05707.7 KEG09782.1 - 0.028 13.8 0.1 3.1 7.2 0.0 2.5 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_28 PF13521.1 KEG09782.1 - 0.059 13.3 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 KEG09782.1 - 0.073 13.1 0.0 3.8 7.5 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF2075 PF09848.4 KEG09782.1 - 0.076 11.9 0.1 0.16 10.8 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_29 PF13555.1 KEG09782.1 - 0.077 12.5 0.4 0.33 10.5 0.1 2.2 3 0 0 3 3 3 0 P-loop containing region of AAA domain IstB_IS21 PF01695.12 KEG09782.1 - 0.077 12.4 0.3 0.17 11.3 0.2 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein CPT PF07931.7 KEG09782.1 - 0.081 12.5 0.3 0.43 10.1 0.0 2.3 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.1 KEG09782.1 - 0.1 12.4 0.0 0.31 10.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KEG09782.1 - 0.12 12.6 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain SUV3_C PF12513.3 KEG09783.1 - 3.5e-13 48.7 0.6 8.3e-13 47.5 0.4 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 KEG09783.1 - 6.5e-08 32.3 0.0 1.2e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEG09783.1 - 0.0065 15.9 0.0 0.02 14.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Kinesin PF00225.18 KEG09783.1 - 0.18 10.4 0.0 0.28 9.8 0.0 1.2 1 0 0 1 1 1 0 Kinesin motor domain Hydrolase PF00702.21 KEG09784.1 - 1.6e-14 54.8 0.2 1.7e-09 38.4 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEG09784.1 - 1.4e-11 44.9 1.2 2.5e-10 40.8 0.8 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEG09784.1 - 1.1e-07 31.7 0.0 2.9e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit E1-E2_ATPase PF00122.15 KEG09784.1 - 1.2e-07 30.9 0.1 4.3e-07 29.2 0.1 2.0 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.7 KEG09784.1 - 0.0081 15.7 0.2 0.02 14.4 0.0 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DNA_topoisoIV PF00521.15 KEG09786.1 - 8e-100 334.6 0.0 1.5e-99 333.7 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A Toprim PF01751.17 KEG09786.1 - 7.9e-12 45.0 0.0 2.1e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Toprim domain DNA_gyraseB PF00204.20 KEG09786.1 - 1.2e-09 37.5 0.0 2.6e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.21 KEG09786.1 - 1.1e-05 25.1 0.0 2.4e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KEG09786.1 - 1.7e-05 24.5 0.0 3.6e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UCH PF00443.24 KEG09787.1 - 1.6e-35 122.4 0.0 2.3e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEG09787.1 - 2.6e-22 79.6 0.0 3.8e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.3 KEG09787.1 - 6.9e-06 25.4 0.0 0.066 12.4 0.0 3.5 3 1 1 4 4 4 2 ICP0-binding domain of Ubiquitin-specific protease 7 CorA PF01544.13 KEG09788.1 - 3.1e-28 98.6 0.9 5.8e-24 84.6 0.2 2.1 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein SHOCT PF09851.4 KEG09789.1 - 9.6e-06 24.8 0.4 1.5e-05 24.2 0.3 1.3 1 0 0 1 1 1 1 Short C-terminal domain Actin PF00022.14 KEG09790.1 - 4.2e-91 305.2 0.0 4.9e-91 305.0 0.0 1.0 1 0 0 1 1 1 1 Actin TMEM154 PF15102.1 KEG09791.1 - 0.071 12.8 0.0 0.088 12.5 0.0 1.1 1 0 0 1 1 1 0 TMEM154 protein family DUF3595 PF12166.3 KEG09793.1 - 1.8e-102 343.3 0.0 2.9e-102 342.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3595) CAP_N PF01213.14 KEG09793.1 - 0.19 10.9 3.2 0.55 9.4 2.2 1.7 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal IMS PF00817.15 KEG09797.1 - 8.7e-36 122.9 0.7 3.3e-35 121.0 0.0 2.2 2 1 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 KEG09797.1 - 1.3e-10 41.2 0.9 2.7e-10 40.2 0.6 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KEG09797.1 - 6.4e-06 25.9 0.0 1.5e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif ANTH PF07651.11 KEG09797.1 - 0.031 12.9 0.5 0.058 12.0 0.3 1.3 1 0 0 1 1 1 0 ANTH domain IMS PF00817.15 KEG09798.1 - 1.3e-05 25.0 0.0 4.2e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 impB/mucB/samB family IMS_HHH PF11798.3 KEG09798.1 - 0.011 15.7 0.0 0.028 14.4 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif Peptidase_M8 PF01457.11 KEG09800.1 - 6.1e-137 457.0 0.0 8.3e-137 456.6 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin Reprolysin_3 PF13582.1 KEG09800.1 - 0.034 14.6 0.1 0.1 13.1 0.1 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Erythrovirus_X PF06795.6 KEG09801.1 - 0.0091 15.9 0.0 0.1 12.6 0.0 2.2 2 0 0 2 2 2 1 Erythrovirus X protein Ribosomal_60s PF00428.14 KEG09801.1 - 3.1 8.2 12.5 0.46 10.9 3.2 2.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein CDC45 PF02724.9 KEG09802.1 - 0.91 7.4 5.8 1.2 7.1 0.1 2.1 2 0 0 2 2 2 0 CDC45-like protein Ank_5 PF13857.1 KEG09803.1 - 4.9e-13 48.8 0.1 6.2e-05 23.1 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KEG09803.1 - 2.7e-12 46.8 0.0 8.3e-12 45.2 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) C2 PF00168.25 KEG09803.1 - 1.4e-11 44.0 0.0 2.5e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain Ank PF00023.25 KEG09803.1 - 1.8e-11 43.2 0.0 2.3e-05 23.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 KEG09803.1 - 3.9e-11 43.1 0.1 0.00015 22.2 0.0 2.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEG09803.1 - 1.1e-09 37.6 0.0 0.00078 19.4 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat RAP1 PF07218.6 KEG09803.1 - 5.3 5.0 5.0 7.2 4.5 3.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) YEATS PF03366.11 KEG09804.1 - 1.6e-19 69.4 0.1 2.9e-19 68.5 0.1 1.4 1 0 0 1 1 1 1 YEATS family PALP PF00291.20 KEG09805.1 - 4e-46 157.6 0.6 4.6e-46 157.4 0.4 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF3863 PF12979.2 KEG09806.1 - 0.14 10.7 0.0 0.23 9.9 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) Mito_carr PF00153.22 KEG09808.1 - 7.9e-38 128.0 1.6 3.2e-16 58.7 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3176 PF11374.3 KEG09808.1 - 0.0044 16.8 0.1 0.037 13.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Sec20 PF03908.8 KEG09809.1 - 5.8e-05 22.7 2.4 0.00028 20.5 0.2 2.1 1 1 1 2 2 2 1 Sec20 V-SNARE_C PF12352.3 KEG09809.1 - 0.027 14.5 1.8 0.038 14.0 1.0 1.4 1 1 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus Rnk_N PF14760.1 KEG09809.1 - 0.079 13.0 1.4 0.52 10.4 1.0 2.1 1 1 0 1 1 1 0 Rnk N-terminus Troponin PF00992.15 KEG09810.1 - 0.074 13.1 1.4 0.091 12.8 1.0 1.1 1 0 0 1 1 1 0 Troponin DUF308 PF03729.8 KEG09811.1 - 0.12 12.3 0.0 0.12 12.3 0.0 2.0 2 1 0 2 2 2 0 Short repeat of unknown function (DUF308) HSP33 PF01430.14 KEG09812.1 - 3.5e-12 46.0 4.3 9.5e-06 24.9 0.0 3.0 2 1 1 3 3 3 2 Hsp33 protein Arm PF00514.18 KEG09813.1 - 1.5e-62 205.4 17.8 4.1e-09 35.9 0.0 9.1 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 KEG09813.1 - 2.4e-17 62.8 9.9 4.9e-05 23.6 0.0 6.2 6 1 2 8 8 8 4 HEAT-like repeat HEAT_2 PF13646.1 KEG09813.1 - 7.9e-16 58.1 0.7 0.00017 21.8 0.1 4.9 2 1 3 5 5 5 5 HEAT repeats HEAT PF02985.17 KEG09813.1 - 4.4e-11 41.8 0.5 2 8.7 0.0 7.6 7 1 0 7 7 7 2 HEAT repeat RICTOR_V PF14668.1 KEG09813.1 - 0.00019 21.3 1.9 3.5 7.6 0.0 5.3 5 1 1 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 Proteasom_PSMB PF10508.4 KEG09813.1 - 0.0053 15.0 0.0 0.0087 14.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit Arm_2 PF04826.8 KEG09813.1 - 0.035 13.2 0.0 21 4.0 0.0 3.3 3 1 0 3 3 3 0 Armadillo-like YadA_stalk PF05662.9 KEG09813.1 - 2.5 8.0 5.6 12 5.8 0.3 3.6 3 0 0 3 3 3 0 Coiled stalk of trimeric autotransporter adhesin MA3 PF02847.12 KEG09814.1 - 6e-08 32.3 0.1 2.3e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 MA3 domain Med25_NR-box PF11244.3 KEG09814.1 - 0.21 12.0 1.5 0.47 10.9 1.1 1.5 1 0 0 1 1 1 0 Mediator complex subunit 25 C-terminal NR box-containing zf-DHHC PF01529.15 KEG09816.1 - 2.9e-35 121.1 3.0 2.9e-35 121.1 2.1 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF4118 PF13493.1 KEG09816.1 - 5 7.3 15.2 5.7 7.1 4.6 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4118) NUDIX PF00293.23 KEG09817.1 - 8.2e-14 51.4 0.1 1.2e-13 50.8 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain CitG PF01874.11 KEG09819.1 - 0.042 13.0 0.0 0.052 12.7 0.0 1.3 1 0 0 1 1 1 0 ATP:dephospho-CoA triphosphoribosyl transferase DUF676 PF05057.9 KEG09819.1 - 0.053 12.7 0.0 0.17 11.1 0.0 1.7 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Pyridox_ox_2 PF12900.2 KEG09819.1 - 0.1 12.3 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase SET PF00856.23 KEG09820.1 - 1.1e-10 42.1 0.0 5e-09 36.6 0.0 2.2 2 1 0 2 2 2 1 SET domain CpXC PF14353.1 KEG09820.1 - 0.0035 17.2 1.8 0.056 13.4 0.1 2.3 2 0 0 2 2 2 1 CpXC protein RLAN PF14401.1 KEG09820.1 - 0.039 13.4 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 RimK-like ATPgrasp N-terminal domain Na_H_Exchanger PF00999.16 KEG09821.1 - 2.3e-41 141.6 45.9 3.8e-41 140.8 31.8 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TPR_19 PF14559.1 KEG09822.1 - 9.1e-06 25.9 2.9 0.043 14.1 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 KEG09822.1 - 5e-05 23.1 0.8 1 9.7 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KEG09822.1 - 0.00016 21.1 0.2 0.037 13.7 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEG09822.1 - 0.0051 16.3 2.0 1.4 8.6 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KEG09822.1 - 0.016 15.7 1.7 39 5.2 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KEG09822.1 - 0.034 14.0 0.0 0.11 12.3 0.0 1.9 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.1 KEG09822.1 - 0.1 12.2 3.1 4 7.1 0.0 3.4 4 0 0 4 4 4 0 TPR repeat TPR_10 PF13374.1 KEG09822.1 - 0.13 12.2 0.8 5.5 7.0 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 KEG09822.1 - 0.21 11.6 4.8 16 5.7 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Methyltransf_28 PF02636.12 KEG09823.1 - 2.5e-58 197.4 0.1 3.4e-58 197.0 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DnaI_N PF07319.6 KEG09823.1 - 0.07 13.3 0.3 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 Primosomal protein DnaI N-terminus DUF360 PF04020.8 KEG09824.1 - 0.032 14.5 0.2 0.032 14.5 0.2 2.7 4 0 0 4 4 4 0 Membrane protein of unknown function ARL6IP6 PF15062.1 KEG09824.1 - 0.07 13.0 0.2 0.52 10.2 0.0 2.3 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix tRNA_edit PF04073.10 KEG09826.1 - 9.5e-09 35.1 0.0 4.1e-08 33.1 0.0 2.0 2 1 0 2 2 2 1 Aminoacyl-tRNA editing domain tRNA-synt_2 PF00152.15 KEG09827.1 - 1.3e-70 237.7 0.0 1.8e-70 237.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KEG09827.1 - 3.7e-09 36.3 0.0 7e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KEG09827.1 - 4.6e-05 22.7 0.1 0.015 14.4 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) PMT_C PF11647.3 KEG09827.1 - 0.059 12.9 0.0 0.73 9.4 0.0 2.3 2 0 0 2 2 2 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 Erythro_esteras PF05139.9 KEG09827.1 - 0.088 11.9 0.0 2.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Erythromycin esterase MutS_V PF00488.16 KEG09828.1 - 2.1e-43 148.4 0.0 4.8e-43 147.2 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KEG09828.1 - 2e-20 73.4 0.1 3.8e-20 72.5 0.1 1.4 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 KEG09828.1 - 1.3e-07 31.7 0.0 4.8e-07 29.9 0.0 2.0 2 0 0 2 2 1 1 MutS domain II AAA_22 PF13401.1 KEG09828.1 - 9.8e-05 22.5 0.1 0.0022 18.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain MutS_IV PF05190.13 KEG09828.1 - 0.0015 18.7 0.0 0.0048 17.0 0.0 1.8 1 0 0 1 1 1 1 MutS family domain IV AAA_16 PF13191.1 KEG09828.1 - 0.0021 18.0 0.2 0.024 14.6 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 KEG09828.1 - 0.0046 16.8 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KEG09828.1 - 0.0046 16.4 0.0 0.014 14.8 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF2638 PF10937.3 KEG09828.1 - 0.011 16.7 0.6 0.057 14.4 0.1 2.5 2 0 0 2 2 1 0 Protein of unknown function (DUF2638) AAA_23 PF13476.1 KEG09828.1 - 0.013 15.8 1.3 0.016 15.5 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_17 PF13207.1 KEG09828.1 - 0.018 15.8 0.0 0.1 13.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 KEG09828.1 - 0.072 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KEG09828.1 - 0.15 12.2 0.0 0.36 11.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KEG09828.1 - 0.32 10.6 0.0 0.8 9.3 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase CDC45 PF02724.9 KEG09828.1 - 4.9 5.0 10.0 7.9 4.3 6.9 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4499 PF14934.1 KEG09829.1 - 0.00031 20.6 0.3 0.00031 20.6 0.2 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4499) DUF3995 PF13160.1 KEG09830.1 - 0.078 13.0 0.1 0.083 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3995) ABC2_membrane PF01061.19 KEG09831.1 - 1.9e-08 33.7 24.7 2.7e-08 33.2 17.1 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 KEG09831.1 - 4.7e-07 30.1 0.0 7.9e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SbcCD_C PF13558.1 KEG09831.1 - 0.12 12.2 0.1 20 5.1 0.0 2.5 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PDR_CDR PF06422.7 KEG09831.1 - 0.15 11.7 3.1 4.6 6.9 0.0 3.8 4 0 0 4 4 4 0 CDR ABC transporter zf-C2HC_2 PF13913.1 KEG09832.1 - 9.5e-12 44.2 26.9 1.9e-08 33.7 1.7 3.6 3 0 0 3 3 3 2 zinc-finger of a C2HC-type DUF329 PF03884.9 KEG09832.1 - 0.017 14.6 7.9 0.029 13.9 2.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF329) zf-C2H2 PF00096.21 KEG09832.1 - 0.069 13.5 11.7 6.2 7.3 0.3 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-RING_3 PF14369.1 KEG09832.1 - 0.086 12.8 4.8 3.4 7.7 0.1 2.8 2 0 0 2 2 2 0 zinc-finger Zn-ribbon_8 PF09723.5 KEG09832.1 - 0.41 10.6 9.0 2.9 7.9 0.0 3.4 3 0 0 3 3 3 0 Zinc ribbon domain zf-H2C2_2 PF13465.1 KEG09832.1 - 0.56 10.6 5.8 6.9 7.1 0.5 2.7 2 0 0 2 2 2 0 Zinc-finger double domain Rad50_zn_hook PF04423.9 KEG09832.1 - 0.9 9.0 4.3 0.85 9.1 0.2 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif Lar_restr_allev PF14354.1 KEG09832.1 - 5.3 7.4 10.5 0.35 11.2 0.3 3.2 3 0 0 3 3 3 0 Restriction alleviation protein Lar MatE PF01554.13 KEG09833.1 - 2.8e-32 111.5 27.0 3.6e-19 68.9 6.2 2.6 2 0 0 2 2 2 2 MatE FAM176 PF14851.1 KEG09833.1 - 6.7e-06 25.8 1.2 3.1e-05 23.6 0.1 2.3 2 0 0 2 2 2 1 FAM176 family Myc_N PF01056.13 KEG09833.1 - 0.11 11.6 12.0 0.052 12.7 3.5 2.3 2 0 0 2 2 2 0 Myc amino-terminal region Nucleoplasmin PF03066.10 KEG09833.1 - 0.4 10.1 14.9 2.8 7.4 5.5 2.3 2 0 0 2 2 2 0 Nucleoplasmin Mak16 PF04874.9 KEG09833.1 - 3.7 7.7 20.3 4.1 7.5 7.5 2.2 2 0 0 2 2 2 0 Mak16 protein C-terminal region CENP-B_dimeris PF09026.5 KEG09833.1 - 4.9 7.4 17.6 4.3 7.6 6.3 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain MENTAL PF10457.4 KEG09834.1 - 0.11 12.0 0.1 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Cholesterol-capturing domain DUF607 PF04678.8 KEG09835.1 - 2e-43 148.4 0.0 2.9e-43 147.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF607 Pkinase PF00069.20 KEG09836.1 - 0.00021 20.5 0.0 0.00034 19.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KEG09836.1 - 0.1 11.5 0.0 0.21 10.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Dabb PF07876.7 KEG09837.1 - 4.4e-12 46.2 0.1 5.5e-12 45.9 0.1 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain nsp8 PF08717.5 KEG09837.1 - 0.01 15.4 0.0 0.013 15.1 0.0 1.3 1 1 0 1 1 1 0 nsp8 replicase YtpI PF14007.1 KEG09837.1 - 0.034 14.0 0.0 0.048 13.5 0.0 1.2 1 0 0 1 1 1 0 YtpI-like protein Cecropin PF00272.14 KEG09837.1 - 0.063 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Cecropin family Dabb PF07876.7 KEG09838.1 - 7e-15 55.2 0.0 8.3e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain HTH_5 PF01022.15 KEG09838.1 - 0.12 12.0 0.0 1.4 8.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family UCH PF00443.24 KEG09839.1 - 8.6e-49 166.0 0.0 1.4e-48 165.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEG09839.1 - 9.4e-15 54.8 0.0 1.8e-14 53.9 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Pkinase PF00069.20 KEG09840.1 - 0.00047 19.3 0.1 0.7 8.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain SNF2_N PF00176.18 KEG09841.1 - 2.7e-32 111.7 0.0 4e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEG09841.1 - 2.2e-09 37.0 0.0 5.3e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEG09841.1 - 5.3e-08 32.5 0.0 6.8e-07 28.9 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 KEG09841.1 - 0.00018 21.3 0.0 0.0037 17.1 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CytochromB561_N PF09786.4 KEG09841.1 - 2.1 6.6 4.3 4 5.7 3.0 1.3 1 0 0 1 1 1 0 Cytochrome B561, N terminal Npa1 PF11707.3 KEG09842.1 - 8.8e-08 31.5 0.0 2.1e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal Pkinase PF00069.20 KEG09843.1 - 1.3e-60 204.7 0.0 1.9e-60 204.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG09843.1 - 1.3e-27 96.5 0.0 1.8e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_6 PF13405.1 KEG09843.1 - 1.3e-07 30.8 3.2 0.029 14.2 0.0 4.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 KEG09843.1 - 4.4e-06 26.7 5.3 0.034 14.2 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain pair Kinase-like PF14531.1 KEG09843.1 - 1.8e-05 23.8 0.0 5.6e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like EF-hand_1 PF00036.27 KEG09843.1 - 8.6e-05 21.5 0.8 2.1 7.8 0.0 4.6 4 0 0 4 4 4 1 EF hand Kdo PF06293.9 KEG09843.1 - 0.0045 16.0 0.0 0.014 14.5 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_8 PF13833.1 KEG09843.1 - 0.036 13.7 3.0 0.87 9.2 0.3 3.6 2 2 1 3 3 3 0 EF-hand domain pair DUF1456 PF07308.8 KEG09843.1 - 0.24 11.4 1.0 1.9 8.5 0.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1456) Noelin-1 PF12308.3 KEG09845.1 - 0.016 15.0 0.1 0.047 13.4 0.1 1.8 1 0 0 1 1 1 0 Neurogenesis glycoprotein SHIPPO-rpt PF07004.7 KEG09846.1 - 0.00016 22.3 46.9 1.6 9.8 0.8 10.8 10 2 0 10 10 10 6 Sperm-tail PG-rich repeat Ribosomal_S3Ae PF01015.13 KEG09847.1 - 8e-63 211.2 6.4 9.9e-63 210.9 4.4 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Salp15 PF12115.3 KEG09847.1 - 0.12 12.5 0.5 12 6.1 0.1 2.3 1 1 1 2 2 2 0 Salivary protein of 15kDa inhibits CD4+ T cell activation Integrase_AP2 PF14657.1 KEG09847.1 - 0.44 10.3 5.8 1 9.1 4.0 1.7 1 0 0 1 1 1 0 AP2-like DNA-binding integrase domain zf-C3HC4_3 PF13920.1 KEG09850.1 - 0.31 10.7 13.4 0.58 9.8 9.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEG09850.1 - 2.3 8.3 15.7 3.9 7.5 10.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.20 KEG09853.1 - 1.7e-06 27.3 0.0 2.5e-05 23.5 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain PaaSYMP PF14738.1 KEG09855.1 - 5.3e-44 149.6 8.5 5.3e-44 149.6 5.9 2.2 2 0 0 2 2 2 1 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 DUF3773 PF12608.3 KEG09857.1 - 7e-11 42.0 1.3 1.5e-10 40.9 0.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3773) DUF3439 PF11921.3 KEG09857.1 - 0.24 11.1 6.1 0.12 12.1 1.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) PPP4R2 PF09184.6 KEG09857.1 - 0.95 8.9 5.9 1.5 8.3 4.1 1.2 1 0 0 1 1 1 0 PPP4R2 Mucin PF01456.12 KEG09857.1 - 3.1 7.5 17.8 6.2 6.5 0.5 2.6 3 0 0 3 3 3 0 Mucin-like glycoprotein Mucin PF01456.12 KEG09859.1 - 1e-05 25.3 15.7 6.1e-05 22.8 4.4 2.7 2 1 0 2 2 2 2 Mucin-like glycoprotein SSP160 PF06933.6 KEG09859.1 - 0.45 8.4 7.7 0.57 8.0 5.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 P12 PF12669.2 KEG09859.1 - 1.6 9.0 5.0 0.22 11.7 0.3 2.0 2 0 0 2 2 2 0 Virus attachment protein p12 family Enterotoxin_HS1 PF08090.6 KEG09860.1 - 1.4 8.7 9.5 5.3 6.8 4.5 2.6 2 0 0 2 2 2 0 Heat stable E.coli enterotoxin 1 Ribosomal_L28e PF01778.12 KEG09860.1 - 9.8 6.6 9.3 0.19 12.1 1.0 2.1 2 1 1 3 3 3 0 Ribosomal L28e protein family BicD PF09730.4 KEG09862.1 - 0.053 11.8 0.1 0.054 11.8 0.0 1.0 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D Aminotran_5 PF00266.14 KEG09863.1 - 1e-11 44.2 0.0 1.4e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KEG09863.1 - 0.0081 15.2 0.1 0.011 14.8 0.1 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 KEG09863.1 - 0.057 11.6 0.0 0.074 11.3 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Epimerase PF01370.16 KEG09865.1 - 3.1e-57 193.7 0.1 3.8e-57 193.4 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KEG09865.1 - 5.9e-21 74.5 0.0 8.4e-21 74.0 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KEG09865.1 - 5.7e-19 68.1 0.0 1.3e-18 66.9 0.0 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 KEG09865.1 - 8.8e-18 64.1 0.1 1.7e-16 59.9 0.0 2.4 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 KEG09865.1 - 4.6e-16 58.3 0.1 6.4e-16 57.8 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 KEG09865.1 - 0.00035 19.9 0.1 0.001 18.3 0.1 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEG09865.1 - 0.002 18.1 0.0 0.0045 17.0 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KEG09865.1 - 0.069 13.0 0.0 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 short chain dehydrogenase NAD_binding_2 PF03446.10 KEG09865.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Ribosomal_L38e PF01781.13 KEG09867.1 - 1.5e-30 104.7 5.6 1.8e-30 104.5 3.9 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family DUF2359 PF10151.4 KEG09867.1 - 0.063 11.8 0.1 0.063 11.8 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2359) PNRC PF15365.1 KEG09868.1 - 0.011 15.7 3.3 0.014 15.4 0.7 2.4 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator Utp12 PF04003.7 KEG09868.1 - 1.3 9.0 6.8 1.6 8.6 0.3 2.8 2 1 0 2 2 2 0 Dip2/Utp12 Family HlyIII PF03006.15 KEG09869.1 - 3.8e-22 78.7 13.6 4.8e-22 78.4 9.4 1.1 1 0 0 1 1 1 1 Haemolysin-III related Mito_fiss_Elm1 PF06258.6 KEG09869.1 - 0.031 13.2 0.0 0.044 12.7 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial fission ELM1 Glycos_transf_1 PF00534.15 KEG09871.1 - 1.7e-11 43.8 0.0 2.8e-09 36.6 0.0 2.4 3 0 0 3 3 3 2 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KEG09871.1 - 2.9e-06 27.4 0.4 7.7e-05 22.8 0.0 3.2 3 1 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KEG09871.1 - 7e-05 22.9 0.0 0.00027 21.1 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 Myc_target_1 PF15179.1 KEG09872.1 - 0.0011 18.6 0.1 0.0011 18.5 0.0 1.1 1 0 0 1 1 1 1 Myc target protein 1 DUF805 PF05656.9 KEG09872.1 - 0.055 13.2 0.8 0.51 10.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF805) RRM_1 PF00076.17 KEG09873.1 - 1.9e-19 69.0 0.0 3.9e-13 48.8 0.0 2.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG09873.1 - 1.1e-12 47.7 0.0 4.6e-09 36.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG09873.1 - 3.5e-08 33.1 0.0 2.1e-07 30.6 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 KEG09873.1 - 0.0076 16.2 0.0 2.9 7.9 0.0 2.3 2 0 0 2 2 2 2 RNA binding domain TPR_12 PF13424.1 KEG09874.1 - 3.3e-65 216.0 49.4 5e-14 51.9 0.1 8.2 7 1 1 8 8 8 7 Tetratricopeptide repeat TPR_10 PF13374.1 KEG09874.1 - 4.3e-35 118.6 36.2 3.5e-05 23.5 0.0 11.8 12 0 0 12 12 12 10 Tetratricopeptide repeat TPR_11 PF13414.1 KEG09874.1 - 2.6e-25 87.8 50.6 3.6e-06 26.5 1.1 8.1 7 1 1 8 8 8 7 TPR repeat TPR_2 PF07719.12 KEG09874.1 - 8.9e-19 65.8 55.3 0.027 14.3 0.1 12.6 12 1 0 12 12 12 8 Tetratricopeptide repeat TPR_1 PF00515.23 KEG09874.1 - 1.6e-17 62.2 49.3 0.055 13.0 0.1 13.1 14 0 0 14 14 14 7 Tetratricopeptide repeat TPR_14 PF13428.1 KEG09874.1 - 1.9e-15 55.9 39.1 0.019 15.5 0.4 11.8 6 2 5 11 11 11 5 Tetratricopeptide repeat TPR_16 PF13432.1 KEG09874.1 - 4.4e-15 55.8 42.9 0.00063 20.3 0.0 9.2 5 3 4 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.1 KEG09874.1 - 2.1e-11 42.7 37.7 0.064 13.0 0.8 11.2 12 0 0 12 12 12 5 Tetratricopeptide repeat TPR_7 PF13176.1 KEG09874.1 - 4.5e-10 38.5 34.5 0.24 11.2 0.0 11.0 12 1 1 13 13 13 3 Tetratricopeptide repeat TPR_19 PF14559.1 KEG09874.1 - 4.1e-05 23.8 40.0 0.11 12.8 0.7 8.9 5 3 7 12 12 12 3 Tetratricopeptide repeat Apc5 PF12862.2 KEG09874.1 - 0.087 12.6 20.0 0.4 10.5 0.4 6.5 4 2 1 5 5 5 0 Anaphase-promoting complex subunit 5 Exo_endo_phos PF03372.18 KEG09875.1 - 2.8e-08 34.0 0.3 6.7e-08 32.7 0.2 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3319 PF11782.3 KEG09875.1 - 0.005 16.6 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3319) SET PF00856.23 KEG09877.1 - 5.9e-12 46.1 1.3 0.0022 18.3 0.0 3.6 4 0 0 4 4 4 3 SET domain FHA PF00498.21 KEG09878.1 - 0.013 15.5 0.0 0.084 12.9 0.0 2.4 2 1 0 2 2 2 0 FHA domain Inhibitor_Mig-6 PF11555.3 KEG09878.1 - 1.2 9.6 7.6 5.5 7.4 1.0 2.9 3 0 0 3 3 3 0 EGFR receptor inhibitor Mig-6 PA28_beta PF02252.13 KEG09879.1 - 2.9e-08 33.3 0.2 1.7e-06 27.5 0.1 2.6 3 0 0 3 3 3 1 Proteasome activator pa28 beta subunit Paramyxo_C PF01692.13 KEG09879.1 - 0.014 15.0 0.4 0.02 14.5 0.3 1.2 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c CBS PF00571.23 KEG09881.1 - 0.0044 16.7 0.0 0.0063 16.2 0.0 1.3 1 0 0 1 1 1 1 CBS domain F-box-like PF12937.2 KEG09882.1 - 0.0024 17.5 0.2 0.0043 16.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KEG09882.1 - 0.04 13.5 0.0 0.073 12.7 0.0 1.4 1 0 0 1 1 1 0 F-box domain Spt5_N PF11942.3 KEG09883.1 - 2.4 8.8 20.6 3.8 8.2 5.5 3.3 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal RNase_H2_suC PF08615.6 KEG09883.1 - 5.8 6.7 7.6 53 3.6 4.1 2.8 2 1 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) AvrPto PF11592.3 KEG09885.1 - 0.078 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Central core of the bacterial effector protein AvrPto DUF488 PF04343.8 KEG09886.1 - 0.013 15.9 0.8 0.021 15.1 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF488 ORC6 PF05460.8 KEG09886.1 - 0.03 13.4 0.1 0.037 13.1 0.1 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) HTH_28 PF13518.1 KEG09886.1 - 0.054 13.5 2.1 0.12 12.4 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_29 PF13551.1 KEG09886.1 - 0.061 13.4 1.6 4.6 7.4 0.1 2.4 1 1 1 2 2 2 0 Winged helix-turn helix Synaptobrevin PF00957.16 KEG09886.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Synaptobrevin PYC_OADA PF02436.13 KEG09886.1 - 0.17 11.2 0.2 0.23 10.8 0.2 1.1 1 0 0 1 1 1 0 Conserved carboxylase domain HTH_23 PF13384.1 KEG09886.1 - 0.18 11.4 1.0 0.64 9.7 0.1 2.4 3 1 0 3 3 3 0 Homeodomain-like domain DUF3592 PF12158.3 KEG09886.1 - 1.2 8.8 6.9 3 7.6 4.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3592) Pex14_N PF04695.8 KEG09886.1 - 1.5 8.8 8.6 2.2 8.3 0.2 2.3 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1682 PF07946.9 KEG09886.1 - 4.9 5.8 6.5 1.3 7.8 0.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1682) MotA_ExbB PF01618.11 KEG09887.1 - 0.12 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family PSP1 PF04468.7 KEG09888.1 - 1.7e-25 88.7 0.3 2.9e-25 88.0 0.2 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Epimerase PF01370.16 KEG09891.1 - 1.7e-13 50.5 0.0 2.2e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KEG09891.1 - 9.4e-09 34.5 0.0 1.6e-08 33.7 0.0 1.3 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KEG09891.1 - 8.9e-05 22.5 0.0 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KEG09891.1 - 0.071 12.0 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein EF_TS PF00889.14 KEG09892.1 - 2.6e-16 59.6 0.8 3.7e-16 59.1 0.6 1.3 1 0 0 1 1 1 1 Elongation factor TS UBA PF00627.26 KEG09892.1 - 0.0074 16.1 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain BBS2_Mid PF14783.1 KEG09894.1 - 8.3e-06 25.5 0.0 0.00021 21.0 0.0 3.0 2 1 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region FG-GAP PF01839.18 KEG09894.1 - 0.0005 19.6 0.0 0.0085 15.7 0.0 2.4 2 0 0 2 2 2 1 FG-GAP repeat BBS2_C PF14782.1 KEG09894.1 - 0.0034 16.0 0.1 0.3 9.6 0.0 2.4 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, C-terminal CLAMP PF14769.1 KEG09895.1 - 8.8e-05 22.5 0.0 0.00057 19.9 0.0 2.2 2 0 0 2 2 2 1 Flagellar C1a complex subunit C1a-32 TyeA PF09059.5 KEG09895.1 - 0.29 11.0 0.0 0.29 11.0 0.0 2.7 3 0 0 3 3 3 0 TyeA Apo-CII PF05355.6 KEG09896.1 - 0.082 12.7 0.3 0.54 10.1 0.1 2.2 2 1 0 2 2 2 0 Apolipoprotein C-II RRM_1 PF00076.17 KEG09897.1 - 1e-21 76.3 0.0 2.2e-11 43.2 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG09897.1 - 8.3e-18 63.9 0.0 1.1e-06 28.3 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG09897.1 - 2.6e-15 56.1 0.0 3.9e-08 33.1 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Dynein_heavy PF03028.10 KEG09899.1 - 4.7e-198 659.6 0.0 1.2e-196 654.9 0.0 2.5 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 KEG09899.1 - 6.4e-116 387.2 8.6 6.4e-116 387.2 6.0 3.4 4 1 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 KEG09899.1 - 1.3e-95 319.3 0.0 3e-95 318.1 0.0 1.7 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 KEG09899.1 - 8e-67 225.0 0.1 2.5e-66 223.4 0.0 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 KEG09899.1 - 8.4e-56 188.3 0.2 8.4e-56 188.3 0.1 2.8 4 0 0 4 4 4 1 ATP-binding dynein motor region D5 MT PF12777.2 KEG09899.1 - 2.9e-55 187.4 7.2 6.1e-55 186.3 4.8 1.7 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.2 KEG09899.1 - 3.7e-31 108.2 0.0 9.3e-31 106.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 AAA_5 PF07728.9 KEG09899.1 - 7.6e-22 77.5 0.1 7.9e-07 28.8 0.0 5.5 4 2 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA PF00004.24 KEG09899.1 - 1.9e-07 31.3 0.0 0.26 11.4 0.0 5.3 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEG09899.1 - 8.4e-06 25.9 0.7 2.1 8.4 0.0 6.0 5 0 0 5 5 5 1 AAA domain AAA_16 PF13191.1 KEG09899.1 - 1.5e-05 25.0 0.2 0.48 10.3 0.0 5.6 4 1 1 5 5 5 1 AAA ATPase domain AAA_30 PF13604.1 KEG09899.1 - 0.0016 18.0 2.2 0.91 9.0 0.1 4.0 4 0 0 4 4 4 1 AAA domain Reo_sigmaC PF04582.7 KEG09899.1 - 0.0044 16.2 1.1 0.026 13.6 0.0 2.7 2 0 0 2 2 2 1 Reovirus sigma C capsid protein RNA_helicase PF00910.17 KEG09899.1 - 0.017 15.3 0.2 6.6 6.9 0.0 4.1 4 0 0 4 4 3 0 RNA helicase FtsK_SpoIIIE PF01580.13 KEG09899.1 - 0.031 13.7 0.7 10 5.5 0.1 3.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.1 KEG09899.1 - 0.036 14.8 0.0 17 6.2 0.0 4.5 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.1 KEG09899.1 - 0.086 12.3 1.0 10 5.7 0.1 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_19 PF13245.1 KEG09899.1 - 0.3 10.8 5.5 4.9 6.9 0.0 4.0 4 0 0 4 4 4 0 Part of AAA domain DcpS_C PF11969.3 KEG09900.1 - 7.7e-07 29.3 0.0 1.8e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Evr1_Alr PF04777.8 KEG09901.1 - 1.5e-13 50.4 0.1 4.6e-13 48.8 0.1 1.9 1 0 0 1 1 1 1 Erv1 / Alr family Thioredoxin PF00085.15 KEG09901.1 - 2.4e-10 40.0 0.1 3.9e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KEG09901.1 - 0.11 12.6 0.0 0.5 10.5 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin-like Peptidase_M8 PF01457.11 KEG09903.1 - 2.7e-111 372.4 4.2 3.1e-60 204.0 2.5 2.1 2 0 0 2 2 2 2 Leishmanolysin Reprolysin_5 PF13688.1 KEG09903.1 - 0.061 13.2 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12 RRF PF01765.14 KEG09904.1 - 1.3e-16 60.5 0.8 2.1e-16 59.8 0.6 1.3 1 0 0 1 1 1 1 Ribosome recycling factor FAM92 PF06730.6 KEG09904.1 - 0.071 12.4 0.3 0.071 12.4 0.2 1.7 2 0 0 2 2 2 0 FAM92 protein ComGG PF14173.1 KEG09904.1 - 0.1 12.8 0.1 0.29 11.3 0.1 1.7 1 0 0 1 1 1 0 ComG operon protein 7 IF4E PF01652.13 KEG09905.1 - 7.6e-29 100.3 0.0 1.1e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF3678 PF12435.3 KEG09906.1 - 0.006 16.1 2.2 0.0083 15.6 1.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3678) tRNA-synt_2 PF00152.15 KEG09907.1 - 1.3e-72 244.4 0.0 1.8e-72 243.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KEG09907.1 - 1.9e-06 27.6 0.1 3.5e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KEG09907.1 - 0.0012 18.1 0.1 0.14 11.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) SMC_N PF02463.14 KEG09909.1 - 6.7e-32 110.5 0.0 8.5e-32 110.1 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KEG09909.1 - 0.0015 18.5 0.0 0.0019 18.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain DUF4544 PF15077.1 KEG09909.1 - 0.0052 16.3 0.6 0.032 13.7 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4544) SbcCD_C PF13558.1 KEG09909.1 - 0.023 14.5 0.0 0.058 13.3 0.0 1.6 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 KEG09909.1 - 0.089 11.8 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain PhyH PF05721.8 KEG09911.1 - 0.00025 21.1 0.0 0.00033 20.7 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) RF-1 PF00472.15 KEG09912.1 - 3.6e-12 46.1 2.5 3.6e-12 46.1 1.7 3.8 3 1 0 3 3 3 1 RF-1 domain DUF2277 PF10041.4 KEG09912.1 - 0.003 17.4 1.3 0.094 12.6 0.0 2.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2277) Fez1 PF06818.10 KEG09912.1 - 0.011 15.8 28.3 0.61 10.0 14.5 2.8 2 1 0 2 2 2 0 Fez1 Spore_YtfJ PF09579.5 KEG09912.1 - 9.6 6.1 14.8 1.5 8.7 0.5 2.7 2 0 0 2 2 2 0 Sporulation protein YtfJ (Spore_YtfJ) zf-RING_2 PF13639.1 KEG09913.1 - 3.8e-14 52.2 8.9 6e-14 51.6 6.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KEG09913.1 - 1.4e-08 34.6 8.8 2.5e-08 33.7 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEG09913.1 - 1.8e-08 33.9 6.2 2.6e-08 33.3 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KEG09913.1 - 2.1e-08 34.1 4.8 3.9e-08 33.3 3.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KEG09913.1 - 3e-06 26.7 7.3 5.1e-06 26.0 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEG09913.1 - 3.7e-06 26.5 5.4 6.1e-06 25.8 3.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KEG09913.1 - 5.1e-06 26.2 1.6 7.1e-06 25.7 1.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KEG09913.1 - 0.00073 19.1 4.2 0.0015 18.2 2.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_1 PF14446.1 KEG09913.1 - 0.012 15.2 4.9 0.035 13.8 1.4 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 RINGv PF12906.2 KEG09913.1 - 0.05 13.6 5.5 0.12 12.4 3.8 1.6 1 1 0 1 1 1 0 RING-variant domain Baculo_RING PF05883.6 KEG09913.1 - 0.1 12.4 0.4 0.17 11.7 0.3 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-C3HC4_4 PF15227.1 KEG09913.1 - 0.12 12.2 7.9 0.22 11.4 5.5 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 KEG09913.1 - 0.25 10.8 3.8 0.44 10.1 2.6 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 KEG09913.1 - 0.38 10.7 5.6 2.7 8.0 3.9 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 KEG09913.1 - 0.54 9.9 5.6 1.1 9.0 3.9 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.1 KEG09913.1 - 1.7 8.3 7.8 4.3 6.9 5.4 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Synaptobrevin PF00957.16 KEG09914.1 - 1.2e-27 95.3 0.6 1.9e-27 94.7 0.4 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 KEG09914.1 - 0.00011 21.6 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 Regulated-SNARE-like domain SNARE PF05739.14 KEG09914.1 - 0.29 10.8 2.9 0.49 10.1 2.0 1.4 1 0 0 1 1 1 0 SNARE domain PPR_2 PF13041.1 KEG09916.1 - 6.4e-10 38.8 0.0 0.35 10.8 0.0 4.4 4 0 0 4 4 4 3 PPR repeat family PPR PF01535.15 KEG09916.1 - 2.4e-05 23.9 0.2 1.8 8.7 0.2 4.3 4 0 0 4 4 4 2 PPR repeat PPR_3 PF13812.1 KEG09916.1 - 8.2e-05 22.5 3.8 1.5 9.3 0.0 5.6 7 0 0 7 7 7 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 KEG09916.1 - 0.16 11.4 2.6 47 3.5 0.0 4.3 5 0 0 5 5 5 0 PPR repeat LRR_6 PF13516.1 KEG09917.1 - 2.7e-08 33.0 0.1 0.00078 19.2 0.1 3.4 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.2 KEG09917.1 - 6.2e-06 25.6 0.0 1.1e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEG09917.1 - 0.002 17.9 0.1 0.69 10.1 0.0 2.7 2 0 0 2 2 2 2 Leucine Rich Repeat LRR_7 PF13504.1 KEG09917.1 - 0.0026 17.6 0.1 0.3 11.4 0.0 2.7 2 0 0 2 2 2 1 Leucine rich repeat Ycf1 PF05758.7 KEG09918.1 - 0.046 11.4 0.4 0.054 11.2 0.3 1.1 1 0 0 1 1 1 0 Ycf1 TFIIA PF03153.8 KEG09918.1 - 0.054 13.3 16.8 0.068 13.0 11.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4557 PF15101.1 KEG09918.1 - 1.8 8.3 7.9 0.11 12.3 1.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Complex1_LYR_2 PF13233.1 KEG09920.1 - 6.1e-10 39.5 2.0 9.1e-10 38.9 1.4 1.2 1 0 0 1 1 1 1 Complex1_LYR-like DUF922 PF06037.6 KEG09920.1 - 0.074 12.3 0.2 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF922) XH PF03469.9 KEG09920.1 - 0.097 12.3 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 XH domain Las1 PF04031.8 KEG09923.1 - 7.8e-36 123.0 0.0 1.1e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 Las1-like Radial_spoke PF04712.7 KEG09923.1 - 1.5 7.4 6.7 2.2 6.9 4.7 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein DUF4632 PF15451.1 KEG09923.1 - 9.4 6.2 9.8 2.9 7.8 0.9 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4632) DSPc PF00782.15 KEG09926.1 - 2.5e-09 36.7 0.0 5.3e-09 35.7 0.0 1.6 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KEG09926.1 - 5.9e-06 25.8 0.0 1.2e-05 24.7 0.0 1.5 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Mid2 PF04478.7 KEG09926.1 - 0.044 13.2 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor CDKN3 PF05706.7 KEG09926.1 - 0.06 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Radical_SAM PF04055.16 KEG09927.1 - 4.4e-14 52.9 0.0 1.1e-13 51.6 0.0 1.7 1 1 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 KEG09927.1 - 1.3e-08 34.7 0.4 1.1e-06 28.6 0.1 2.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KEG09927.1 - 0.016 15.3 0.2 0.05 13.7 0.1 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CNRIP1 PF15043.1 KEG09927.1 - 0.03 13.6 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 CB1 cannabinoid receptor-interacting protein 1 Abhydrolase_5 PF12695.2 KEG09930.1 - 2.6e-26 92.1 0.0 4.1e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEG09930.1 - 4e-18 66.1 0.1 1.6e-17 64.1 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ank_4 PF13637.1 KEG09930.1 - 1.6e-09 37.9 0.2 3.2e-08 33.8 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Peptidase_S9 PF00326.16 KEG09930.1 - 6.3e-09 35.3 0.3 0.00039 19.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Ank_5 PF13857.1 KEG09930.1 - 1.4e-08 34.7 0.1 1.4e-07 31.5 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KEG09930.1 - 3.5e-08 33.6 0.4 1.5e-07 31.6 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KEG09930.1 - 1.3e-07 31.1 0.1 1.1e-05 25.2 0.0 3.2 3 0 0 3 3 2 1 Ankyrin repeat Peptidase_S15 PF02129.13 KEG09930.1 - 2.1e-06 27.3 0.0 0.033 13.6 0.0 2.3 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Ank PF00023.25 KEG09930.1 - 8.7e-06 25.2 1.9 6.6e-05 22.5 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat AXE1 PF05448.7 KEG09930.1 - 0.00018 20.1 1.0 0.018 13.5 0.5 2.6 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.3 KEG09930.1 - 0.0039 17.0 0.8 0.0097 15.7 0.1 2.1 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 KEG09930.1 - 0.045 13.3 0.2 1.1 8.7 0.1 2.4 1 1 0 2 2 2 0 alpha/beta hydrolase fold Spexin PF15171.1 KEG09930.1 - 0.14 12.2 1.2 0.3 11.0 0.8 1.5 1 0 0 1 1 1 0 Neuropeptide secretory protein family, NPQ, spexin Aminotran_1_2 PF00155.16 KEG09932.1 - 6.9e-78 262.1 0.0 7.8e-78 261.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Actin PF00022.14 KEG09935.1 - 3.7e-81 272.5 0.0 4.7e-81 272.2 0.0 1.1 1 0 0 1 1 1 1 Actin DUF3138 PF11336.3 KEG09936.1 - 0.52 8.4 4.1 1 7.4 2.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) SlyX PF04102.7 KEG09936.1 - 0.52 10.7 11.3 0.93 9.9 1.7 3.7 2 1 1 3 3 3 0 SlyX RrnaAD PF00398.15 KEG09937.1 - 1.8e-28 99.2 0.0 1.3e-27 96.5 0.0 1.9 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.7 KEG09937.1 - 0.0015 18.9 0.1 0.0069 16.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 KEG09937.1 - 0.067 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain CBS PF00571.23 KEG09938.1 - 4.7e-08 32.6 3.2 1.7e-06 27.6 0.8 2.2 2 0 0 2 2 2 2 CBS domain FAD-oxidase_C PF02913.14 KEG09939.1 - 7.8e-32 110.5 0.1 8.4e-32 110.4 0.0 1.0 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KEG09940.1 - 1e-36 125.4 0.8 1.4e-36 124.9 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain FHA PF00498.21 KEG09941.1 - 2.7e-10 40.1 0.0 8.1e-09 35.4 0.0 2.6 1 1 0 1 1 1 1 FHA domain TPR_11 PF13414.1 KEG09942.1 - 4.7e-14 51.7 4.5 2e-08 33.7 1.0 2.3 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.12 KEG09942.1 - 2.8e-07 29.9 1.3 0.04 13.8 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEG09942.1 - 3.6e-06 27.4 0.8 0.016 15.8 0.1 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 KEG09942.1 - 3.1e-05 23.3 0.1 0.049 13.2 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 KEG09942.1 - 7.4e-05 22.5 0.1 0.00027 20.7 0.1 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_15 PF13429.1 KEG09942.1 - 0.0004 19.5 2.6 0.017 14.2 0.1 3.0 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 KEG09942.1 - 0.0028 17.7 0.1 0.033 14.3 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KEG09942.1 - 0.013 16.0 10.6 0.74 10.6 0.1 4.4 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 KEG09942.1 - 0.016 15.1 1.8 0.17 11.8 0.1 2.5 1 1 0 2 2 2 0 Tetratricopeptide repeat ChAPs PF09295.5 KEG09942.1 - 0.024 13.3 0.0 0.033 12.9 0.0 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_8 PF13181.1 KEG09942.1 - 0.033 13.9 0.0 0.33 10.8 0.0 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2999 PF11212.3 KEG09942.1 - 0.055 13.5 0.7 0.11 12.5 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2999) U79_P34 PF03064.11 KEG09942.1 - 0.2 11.1 6.6 0.31 10.5 4.6 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 NARP1 PF12569.3 KEG09942.1 - 0.35 9.5 0.0 0.35 9.5 0.0 2.3 1 1 1 2 2 1 0 NMDA receptor-regulated protein 1 CAF-1_p150 PF11600.3 KEG09942.1 - 1.1 8.5 24.2 1.9 7.7 16.7 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF3523 PF12037.3 KEG09942.1 - 8.1 5.3 22.0 14 4.5 15.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) RR_TM4-6 PF06459.7 KEG09942.1 - 9 6.0 12.4 15 5.3 0.2 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 ArfGap PF01412.13 KEG09943.1 - 1.5e-37 127.9 1.1 1.5e-37 127.9 0.8 2.3 1 1 1 2 2 2 1 Putative GTPase activating protein for Arf Ada3 PF10198.4 KEG09943.1 - 2.9 7.6 7.4 0.61 9.8 1.4 2.2 2 0 0 2 2 2 0 Histone acetyltransferases subunit 3 UBA_4 PF14555.1 KEG09944.1 - 7.6e-07 28.5 0.5 2e-06 27.2 0.4 1.7 1 0 0 1 1 1 1 UBA-like domain zf-met PF12874.2 KEG09946.1 - 0.0074 16.4 0.4 0.013 15.6 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AKAP95 PF04988.7 KEG09946.1 - 0.089 12.5 0.2 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) C2 PF00168.25 KEG09947.1 - 0.0024 17.6 0.0 0.0037 17.0 0.0 1.3 1 0 0 1 1 1 1 C2 domain Radial_spoke_3 PF06098.6 KEG09948.1 - 7.4e-114 379.6 26.7 8.4e-114 379.4 18.5 1.0 1 0 0 1 1 1 1 Radial spoke protein 3 Peptidase_C2 PF00648.16 KEG09949.1 - 8.4e-11 41.4 0.0 1.3e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 KEG09949.1 - 7.8e-09 35.3 0.0 3.1e-08 33.3 0.0 1.9 2 0 0 2 2 2 1 Calpain large subunit, domain III DUF4497 PF14924.1 KEG09949.1 - 0.16 12.2 0.0 33 4.8 0.0 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF4497) DUF787 PF05619.6 KEG09949.1 - 3.9 6.0 0.0 2.9e+02 -0.2 0.0 3.3 4 1 1 5 5 5 0 Borrelia burgdorferi protein of unknown function (DUF787) DUF1253 PF06862.7 KEG09950.1 - 1.3e-51 175.3 1.2 1.5e-51 175.2 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) CST-I PF06002.7 KEG09950.1 - 0.04 13.1 1.0 0.044 13.0 0.1 1.5 2 0 0 2 2 2 0 Alpha-2,3-sialyltransferase (CST-I) Dzip-like_N PF13815.1 KEG09951.1 - 5.4e-39 132.6 1.7 5.4e-39 132.6 1.2 2.5 2 0 0 2 2 2 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf-C2H2 PF00096.21 KEG09951.1 - 0.0001 22.4 1.0 0.00022 21.3 0.7 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type FYDLN_acid PF09538.5 KEG09951.1 - 0.0039 17.7 0.7 0.015 15.8 0.5 2.0 1 0 0 1 1 1 1 Protein of unknown function (FYDLN_acid) zf-Di19 PF05605.7 KEG09951.1 - 0.0045 17.0 0.8 0.0099 15.9 0.6 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 KEG09951.1 - 0.005 17.0 0.8 0.015 15.5 0.6 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger FliD_N PF02465.13 KEG09951.1 - 0.014 15.7 10.1 0.029 14.7 0.9 3.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus zf-C2H2_2 PF12756.2 KEG09951.1 - 0.11 12.5 2.6 0.34 11.0 0.1 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 KEG09951.1 - 0.24 11.7 2.6 3.4 8.1 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double domain Striatin PF08232.7 KEG09951.1 - 0.76 10.0 0.0 0.76 10.0 0.0 3.2 2 1 1 3 3 3 0 Striatin family DUF3138 PF11336.3 KEG09951.1 - 2.3 6.3 7.9 0.76 7.8 2.2 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3138) IncA PF04156.9 KEG09951.1 - 5.8 6.4 18.1 1.2 8.6 4.7 3.4 3 0 0 3 3 3 0 IncA protein mRNA_triPase PF02940.10 KEG09952.1 - 2.8e-12 46.8 0.0 6.1e-12 45.7 0.0 1.5 1 1 0 1 1 1 1 mRNA capping enzyme, beta chain Pyr_redox PF00070.22 KEG09953.1 - 3.1e-10 40.3 0.0 1.7e-05 25.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEG09953.1 - 1e-07 32.0 0.0 0.019 14.8 0.0 3.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEG09953.1 - 1.6e-05 23.9 0.0 0.32 9.8 0.0 3.1 3 0 0 3 3 3 2 Lycopene cyclase protein DAO PF01266.19 KEG09953.1 - 0.00074 18.5 0.0 0.37 9.6 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 KEG09953.1 - 0.0013 18.4 0.0 0.005 16.5 0.0 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 KEG09953.1 - 0.0059 16.0 0.0 0.065 12.6 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_8 PF13450.1 KEG09953.1 - 0.0068 16.4 0.0 2.1 8.4 0.0 3.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 KEG09953.1 - 0.0074 16.5 0.0 1.1 9.5 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding 3HCDH_N PF02737.13 KEG09953.1 - 0.015 14.9 0.0 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 KEG09953.1 - 0.047 13.4 0.0 1.6 8.4 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding F-box PF00646.28 KEG09954.1 - 0.00093 18.7 0.0 0.0023 17.5 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KEG09954.1 - 0.03 14.0 0.1 0.091 12.4 0.1 1.8 1 0 0 1 1 1 0 F-box-like Nudc_N PF14050.1 KEG09955.1 - 2.6e-18 65.7 0.2 5.3e-18 64.7 0.1 1.6 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. CS PF04969.11 KEG09955.1 - 7.8e-16 58.4 0.0 1.4e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 CS domain MerR-DNA-bind PF09278.6 KEG09955.1 - 0.82 10.1 9.7 5.3 7.5 2.0 2.9 3 0 0 3 3 3 0 MerR, DNA binding DUF3987 PF13148.1 KEG09955.1 - 4.5 5.7 11.6 6.9 5.1 8.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF3138 PF11336.3 KEG09955.1 - 6.5 4.8 6.0 9.1 4.3 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Cys_Met_Meta_PP PF01053.15 KEG09956.1 - 3.4e-116 387.6 0.0 4.4e-116 387.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KEG09956.1 - 1.4e-06 27.2 0.1 2.4e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KEG09956.1 - 3.5e-06 26.2 0.0 5.3e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Leu_zip PF15294.1 KEG09956.1 - 0.0021 17.2 0.0 0.0032 16.6 0.0 1.2 1 0 0 1 1 1 1 Leucine zipper DegT_DnrJ_EryC1 PF01041.12 KEG09956.1 - 0.013 14.5 0.2 0.028 13.4 0.1 1.5 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.11 KEG09956.1 - 0.085 11.5 0.1 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein UDPGT PF00201.13 KEG09957.1 - 4e-25 88.3 0.0 8.3e-25 87.3 0.0 1.4 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.15 KEG09957.1 - 0.003 17.3 0.1 0.0076 16.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.11 KEG09957.1 - 0.0058 16.3 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 KEG09957.1 - 0.0083 15.3 0.0 0.017 14.3 0.0 1.4 2 0 0 2 2 2 1 Glycosyl transferase family 1 SPRY PF00622.23 KEG09958.1 - 8.1e-09 35.6 0.0 3.2e-08 33.7 0.0 2.0 1 1 0 1 1 1 1 SPRY domain Hrs_helical PF12210.3 KEG09958.1 - 0.013 15.7 1.0 0.013 15.7 0.7 1.9 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate RFX1_trans_act PF04589.8 KEG09958.1 - 0.019 14.6 1.8 0.041 13.6 1.2 1.5 1 0 0 1 1 1 0 RFX1 transcription activation region DUF563 PF04577.9 KEG09962.1 - 4.8e-20 72.3 0.5 9.9e-20 71.3 0.1 1.7 1 1 0 2 2 2 1 Protein of unknown function (DUF563) IncA PF04156.9 KEG09964.1 - 0.01 15.4 7.2 0.014 15.0 5.0 1.4 1 0 0 1 1 1 0 IncA protein Lipoprotein_7 PF01540.11 KEG09964.1 - 0.015 14.4 0.2 0.017 14.2 0.1 1.1 1 0 0 1 1 1 0 Adhesin lipoprotein HAUS6_N PF14661.1 KEG09964.1 - 0.018 14.4 4.5 0.02 14.2 3.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus HBS1_N PF08938.5 KEG09964.1 - 0.046 13.8 3.4 0.088 12.9 2.1 1.8 1 1 0 1 1 1 0 HBS1 N-terminus KaiC PF06745.8 KEG09964.1 - 0.047 12.8 0.7 0.053 12.6 0.5 1.1 1 0 0 1 1 1 0 KaiC Gene66 PF02053.10 KEG09964.1 - 0.079 12.3 0.2 0.095 12.0 0.1 1.1 1 0 0 1 1 1 0 Gene 66 (IR5) protein Z1 PF10593.4 KEG09964.1 - 0.1 11.7 3.2 0.14 11.3 2.2 1.3 1 1 0 1 1 1 0 Z1 domain TMF_TATA_bd PF12325.3 KEG09964.1 - 0.16 11.6 9.2 0.26 11.0 6.4 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Dec-1 PF04624.9 KEG09964.1 - 0.17 11.5 2.4 0.41 10.3 0.1 2.6 3 0 0 3 3 3 0 Dec-1 repeat APG6 PF04111.7 KEG09964.1 - 0.34 9.9 6.2 0.38 9.7 4.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF948 PF06103.6 KEG09964.1 - 0.43 10.4 2.0 2.5 8.0 0.9 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF972 PF06156.8 KEG09964.1 - 0.44 10.9 7.0 0.96 9.8 2.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) YlqD PF11068.3 KEG09964.1 - 0.78 9.7 9.9 7.6 6.5 6.5 2.0 1 1 1 2 2 2 0 YlqD protein DUF1664 PF07889.7 KEG09964.1 - 1.9 8.2 5.1 3 7.6 3.2 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) L31 PF09784.4 KEG09964.1 - 8.8 6.4 6.8 13 5.9 2.6 2.0 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L31 Glyco_hydro_65m PF03632.10 KEG09965.1 - 5.9e-66 222.6 0.0 9.4e-66 221.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 KEG09965.1 - 4.8e-26 91.6 0.0 1.3e-25 90.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain HAD_2 PF13419.1 KEG09965.1 - 3.8e-05 23.9 0.0 0.0001 22.5 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Glyco_hydro_65C PF03633.10 KEG09965.1 - 0.0013 18.7 0.0 0.0031 17.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain LEM PF03020.10 KEG09965.1 - 0.036 13.5 0.0 0.8 9.2 0.0 2.4 2 0 0 2 2 2 0 LEM domain PRKCSH PF07915.8 KEG09967.1 - 5.4e-11 43.1 0.0 6.3e-10 39.7 0.0 2.5 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 KEG09967.1 - 0.011 15.1 0.1 0.019 14.4 0.1 1.3 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein RVP PF00077.15 KEG09968.1 - 0.15 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Adaptin_N PF01602.15 KEG09970.1 - 6.3e-73 245.8 0.4 8.3e-73 245.4 0.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region AP4E_app_platf PF14807.1 KEG09970.1 - 2.3e-13 50.2 0.2 7e-13 48.7 0.2 1.8 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform HEAT_2 PF13646.1 KEG09970.1 - 3.6e-07 30.3 4.5 0.0082 16.4 0.3 4.4 3 2 1 4 4 4 3 HEAT repeats Cnd1 PF12717.2 KEG09970.1 - 8.5e-06 25.7 0.4 0.0022 17.8 0.2 3.1 1 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KEG09970.1 - 0.013 15.4 4.1 51 4.3 0.1 4.9 4 0 0 4 4 4 0 HEAT repeat CLASP_N PF12348.3 KEG09970.1 - 0.027 13.8 1.0 0.052 12.9 0.1 1.9 2 0 0 2 2 2 0 CLASP N terminal HEAT_EZ PF13513.1 KEG09970.1 - 0.13 12.7 5.4 0.17 12.3 0.0 4.0 4 0 0 4 4 4 0 HEAT-like repeat Flavoprotein PF02441.14 KEG09972.1 - 9.2e-43 144.9 0.1 1.2e-42 144.5 0.1 1.2 1 0 0 1 1 1 1 Flavoprotein AAA PF00004.24 KEG09973.1 - 3.8e-13 49.7 0.0 1.2e-12 48.2 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEG09973.1 - 3.6e-06 27.0 0.0 7.6e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 KEG09973.1 - 4.2e-05 23.2 0.0 7.1e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KEG09973.1 - 0.00013 21.6 0.0 0.00041 20.0 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 KEG09973.1 - 0.00039 21.2 0.0 0.0013 19.5 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 KEG09973.1 - 0.00047 20.3 0.0 0.0013 18.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KEG09973.1 - 0.0029 16.6 0.0 0.0078 15.2 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 KEG09973.1 - 0.0075 15.3 0.0 0.02 14.0 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin DUF815 PF05673.8 KEG09973.1 - 0.0084 15.0 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 KEG09973.1 - 0.0092 15.8 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KEG09973.1 - 0.0098 15.4 0.2 0.036 13.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KEG09973.1 - 0.0099 15.7 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KEG09973.1 - 0.012 15.8 0.2 0.056 13.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KEG09973.1 - 0.015 14.9 0.0 0.04 13.5 0.0 1.8 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.12 KEG09973.1 - 0.017 14.5 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.1 KEG09973.1 - 0.021 14.8 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KEG09973.1 - 0.027 14.6 0.0 0.081 13.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 KEG09973.1 - 0.038 13.3 0.0 0.076 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KEG09973.1 - 0.042 13.4 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 KEG09973.1 - 0.05 13.2 0.0 0.095 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 PPV_E1_C PF00519.12 KEG09973.1 - 0.052 12.1 0.0 0.087 11.4 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase cobW PF02492.14 KEG09973.1 - 0.07 12.5 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Parvo_NS1 PF01057.12 KEG09973.1 - 0.072 11.9 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_24 PF13479.1 KEG09973.1 - 0.085 12.4 0.1 0.17 11.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KEG09973.1 - 0.1 11.6 0.0 0.23 10.5 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_3 PF07726.6 KEG09973.1 - 0.13 11.9 0.0 0.42 10.2 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 KEG09974.1 - 1.1e-05 24.4 0.0 0.00017 20.4 0.0 2.0 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 KEG09974.1 - 0.052 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 KEG09974.1 - 0.058 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain PseudoU_synth_2 PF00849.17 KEG09975.1 - 6.3e-39 133.4 0.0 1e-38 132.7 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase Abhydrolase_6 PF12697.2 KEG09977.1 - 0.00047 20.1 1.4 0.00066 19.6 0.6 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEG09977.1 - 0.0038 16.8 0.0 0.0052 16.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold EF-hand_7 PF13499.1 KEG09978.1 - 1.4e-15 57.1 1.0 3.4e-12 46.3 0.1 3.3 2 2 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KEG09978.1 - 2.5e-07 29.9 0.5 0.0022 17.7 0.0 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 KEG09978.1 - 5.9e-06 25.2 0.2 0.0092 15.2 0.0 3.6 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.1 KEG09978.1 - 0.00026 20.1 0.0 0.001 18.3 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 KEG09978.1 - 0.0053 16.3 0.3 15 5.3 0.0 3.9 5 0 0 5 5 5 2 EF-hand domain pair GRAM PF02893.15 KEG09979.1 - 1e-16 60.2 0.3 2e-07 30.4 0.0 2.6 2 0 0 2 2 2 2 GRAM domain SRP1_TIP1 PF00660.12 KEG09979.1 - 0.042 13.6 0.0 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Seripauperin and TIP1 family adh_short PF00106.20 KEG09982.1 - 4.7e-39 133.9 2.6 4.7e-39 133.9 1.8 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEG09982.1 - 9.7e-18 64.8 0.0 1.3e-17 64.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEG09982.1 - 1.8e-17 63.5 0.9 3.4e-17 62.7 0.6 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEG09982.1 - 4.5e-05 23.0 0.3 5.5e-05 22.7 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KEG09982.1 - 0.0073 16.0 0.4 0.02 14.6 0.3 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ApbA PF02558.11 KEG09982.1 - 0.024 14.0 0.1 0.055 12.9 0.1 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.1 KEG09982.1 - 0.05 13.6 1.6 0.068 13.1 1.1 1.6 1 1 0 1 1 1 0 NADH(P)-binding DAO PF01266.19 KEG09982.1 - 0.051 12.4 1.4 0.13 11.1 0.4 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase DGF-1_5 PF11038.3 KEG09984.1 - 2.3e-132 440.3 12.4 2.3e-132 440.3 8.6 2.7 2 0 0 2 2 2 1 Dispersed gene family protein 1 of Trypanosoma cruzi region 5 DGF-1_C PF11040.3 KEG09984.1 - 9.5e-16 57.4 0.7 2.7e-15 56.0 0.5 1.8 1 0 0 1 1 1 1 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DGF-1_4 PF11024.3 KEG09984.1 - 3.2e-15 56.2 21.6 3.2e-15 56.2 15.0 3.4 2 1 1 3 3 3 1 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 Snapin_Pallidin PF14712.1 KEG09986.1 - 0.00015 21.9 0.1 0.00015 21.9 0.1 1.9 2 0 0 2 2 2 1 Snapin/Pallidin HOOK PF05622.7 KEG09986.1 - 0.011 13.5 0.1 0.011 13.5 0.1 1.4 2 0 0 2 2 2 0 HOOK protein Peptidase_C14 PF00656.17 KEG09986.1 - 0.074 12.7 0.6 1.8 8.2 0.0 2.1 2 0 0 2 2 2 0 Caspase domain Herpes_capsid PF06112.6 KEG09989.1 - 7.9 6.5 9.2 5.1 7.1 3.2 2.1 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Cyt-b5 PF00173.23 KEG09991.1 - 6.5e-42 141.1 0.5 3.4e-22 78.0 0.1 2.1 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Synaptobrevin PF00957.16 KEG09991.1 - 0.25 10.9 1.1 0.26 10.8 0.1 1.6 2 0 0 2 2 2 0 Synaptobrevin Hist_deacetyl PF00850.14 KEG09992.1 - 7.4e-25 87.8 0.2 1.2e-24 87.1 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Hist_deacetyl PF00850.14 KEG09993.1 - 5.4e-29 101.4 0.0 7.4e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 KEG09993.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Arb2 domain RNase_PH PF01138.16 KEG09994.1 - 2.1e-19 70.1 0.0 7e-19 68.4 0.0 1.9 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 SNAP PF14938.1 KEG09995.1 - 5.6e-29 101.1 9.2 8.9e-29 100.5 6.4 1.3 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 KEG09995.1 - 0.049 13.5 11.6 0.055 13.4 0.7 4.2 1 1 4 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.1 KEG09995.1 - 0.077 12.6 8.5 0.078 12.6 0.3 3.7 3 2 0 3 3 3 0 TPR repeat PPR PF01535.15 KEG09995.1 - 0.078 12.9 0.5 1.2 9.2 0.0 3.2 3 0 0 3 3 3 0 PPR repeat GreA_GreB_N PF03449.10 KEG09995.1 - 0.1 12.6 1.9 0.16 12.0 0.1 2.1 3 0 0 3 3 3 0 Transcription elongation factor, N-terminal PPR_3 PF13812.1 KEG09995.1 - 0.17 12.2 0.7 5.8 7.4 0.0 3.8 4 0 0 4 4 4 0 Pentatricopeptide repeat domain TPR_14 PF13428.1 KEG09995.1 - 1.7 9.5 7.9 2.7 8.8 0.5 4.4 3 2 3 6 6 6 0 Tetratricopeptide repeat DUF3617 PF12276.3 KEG09997.1 - 1.4 8.4 4.1 3 7.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3617) PTS_2-RNA PF01885.11 KEG09998.1 - 2.1e-55 186.9 0.0 3.3e-55 186.2 0.0 1.3 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family RNase_T PF00929.19 KEG09998.1 - 6e-19 68.9 0.0 9.5e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Syja_N PF02383.13 KEG09999.1 - 1.5e-68 230.9 0.0 2.1e-68 230.4 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain DUF547 PF04784.9 KEG09999.1 - 9.2e-13 48.1 0.0 2.3e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF547 Sec62 PF03839.11 KEG10001.1 - 0.01 15.2 0.0 0.01 15.2 0.0 2.5 2 1 1 3 3 3 0 Translocation protein Sec62 Myosin_tail_1 PF01576.14 KEG10001.1 - 4.7 4.8 30.9 0.048 11.3 5.7 3.2 3 0 0 3 3 3 0 Myosin tail Aida_C2 PF14186.1 KEG10002.1 - 0.052 12.7 0.9 0.095 11.9 0.1 1.9 2 0 0 2 2 2 0 Cytoskeletal adhesion zf-CCHC PF00098.18 KEG10003.1 - 1.6e-49 163.5 70.5 3e-08 33.2 1.3 8.1 8 0 0 8 8 8 8 Zinc knuckle zf-CCHC_4 PF14392.1 KEG10003.1 - 5.7e-14 51.5 54.2 0.0082 15.7 0.5 8.1 8 0 0 8 8 8 8 Zinc knuckle zf-CCHC_3 PF13917.1 KEG10003.1 - 7e-07 28.8 49.5 0.26 11.0 0.2 8.0 1 1 7 8 8 8 7 Zinc knuckle zf-CCHC_2 PF13696.1 KEG10003.1 - 8.7e-06 25.1 59.1 0.0092 15.4 2.5 8.1 2 2 6 8 8 8 7 Zinc knuckle zf-CCHC_5 PF14787.1 KEG10003.1 - 0.0026 17.2 4.3 0.014 14.8 0.5 7.6 7 1 1 8 8 8 5 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.1 KEG10003.1 - 0.0033 17.0 4.6 0.0033 17.0 3.2 7.5 7 1 1 8 8 8 3 Zinc knuckle zf-CCHC PF00098.18 KEG10004.1 - 1.4e-36 122.6 27.7 1.5e-09 37.3 1.0 4.1 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_3 PF13917.1 KEG10004.1 - 1.7e-10 40.4 20.1 0.0019 17.8 0.5 4.1 2 2 2 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.1 KEG10004.1 - 6.3e-08 32.1 19.7 0.05 13.2 0.4 4.1 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.1 KEG10004.1 - 2.4e-07 30.1 18.1 0.0014 18.1 1.0 4.2 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_6 PF15288.1 KEG10004.1 - 0.018 14.6 28.8 0.33 10.6 0.7 4.2 4 0 0 4 4 4 0 Zinc knuckle IBR PF01485.16 KEG10004.1 - 0.18 11.6 17.3 7.1 6.5 0.2 4.1 4 0 0 4 4 4 0 IBR domain DZR PF12773.2 KEG10004.1 - 0.3 10.9 21.9 1.3e+04 -4.0 15.2 3.6 1 1 0 1 1 1 0 Double zinc ribbon eIF3g PF12353.3 KEG10004.1 - 3.2 7.6 19.4 8.7 6.2 0.4 4.0 3 1 1 4 4 4 0 Eukaryotic translation initiation factor 3 subunit G Proteasome PF00227.21 KEG10005.1 - 5.5e-51 172.5 0.3 6.7e-51 172.2 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit S4 PF01479.20 KEG10006.1 - 3.9e-06 26.1 0.1 2e-05 23.9 0.1 2.1 2 0 0 2 2 2 1 S4 domain PseudoU_synth_2 PF00849.17 KEG10006.1 - 5.2e-05 23.1 0.0 9.5e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase DUF2419 PF10343.4 KEG10007.1 - 6.2e-13 48.6 0.0 1.5e-12 47.4 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2419) Peptidase_M76 PF09768.4 KEG10009.1 - 4.6e-56 188.9 0.3 5.4e-56 188.7 0.2 1.0 1 0 0 1 1 1 1 Peptidase M76 family Peptidase_M91 PF14891.1 KEG10009.1 - 0.027 14.5 0.1 0.043 13.8 0.0 1.3 1 1 0 1 1 1 0 Effector protein Tox-MPTase2 PF15638.1 KEG10009.1 - 0.057 12.9 0.0 0.087 12.3 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase toxin 2 Ribosomal_S27 PF01599.14 KEG10013.1 - 6.9e-20 70.6 3.0 1.6e-19 69.4 2.1 1.7 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.18 KEG10013.1 - 3.1e-05 23.2 2.1 0.0014 17.9 0.0 3.0 2 1 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 KEG10013.1 - 0.00011 21.7 0.0 0.0044 16.6 0.0 2.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.16 KEG10013.1 - 0.0023 17.7 0.3 0.0047 16.7 0.2 1.5 1 0 0 1 1 1 1 IBR domain DnaJ PF00226.26 KEG10014.1 - 4.6e-20 71.1 0.7 8.1e-20 70.3 0.2 1.6 2 0 0 2 2 2 1 DnaJ domain ATP-synt_Eps PF04627.8 KEG10015.1 - 2.1e-08 33.5 0.1 2.6e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain DUF3592 PF12158.3 KEG10016.1 - 4.1e-12 46.1 0.5 4.8e-12 45.8 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3592) RNase_HII PF01351.13 KEG10017.1 - 6.9e-41 140.0 0.0 1e-40 139.5 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII PIG-U PF06728.8 KEG10018.1 - 3.4e-08 32.7 5.2 4.2e-06 25.8 3.6 2.2 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U Cmc1 PF08583.5 KEG10019.1 - 0.38 10.5 3.7 2.5 7.9 0.3 2.9 2 1 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like GlcNAc PF11397.3 KEG10020.1 - 3.2e-24 85.7 0.0 1.6e-14 53.8 0.0 3.7 3 1 0 3 3 3 3 Glycosyltransferase (GlcNAc) Vps51 PF08700.6 KEG10021.1 - 7.5e-12 44.9 0.6 7.5e-12 44.9 0.4 2.4 3 0 0 3 3 3 1 Vps51/Vps67 zf-RING_6 PF14835.1 KEG10021.1 - 0.14 11.9 0.1 0.43 10.3 0.1 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein LUC7 PF03194.10 KEG10021.1 - 0.14 11.6 7.2 0.31 10.5 1.5 2.8 2 1 0 2 2 2 0 LUC7 N_terminus CAF1A PF12253.3 KEG10021.1 - 0.15 12.1 0.9 11 6.1 0.0 2.6 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A zf-C3HC4_3 PF13920.1 KEG10022.1 - 1.6e-14 53.2 4.3 3.7e-14 52.1 3.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.2 KEG10022.1 - 2.1e-10 40.7 0.0 1.5e-08 34.8 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KEG10022.1 - 9.8e-10 37.7 0.2 8.3e-05 22.2 0.2 3.5 3 0 0 3 3 3 2 Ankyrin repeat zf-C3HC4_2 PF13923.1 KEG10022.1 - 3.3e-08 33.4 7.2 7.4e-08 32.2 5.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank_5 PF13857.1 KEG10022.1 - 8.2e-08 32.2 0.2 0.0066 16.6 0.1 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEG10022.1 - 3.3e-07 30.6 0.0 1.8e-05 25.1 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEG10022.1 - 1.3e-06 28.0 0.1 0.0014 18.6 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat zf-RING_2 PF13639.1 KEG10022.1 - 3e-05 23.7 6.4 8.8e-05 22.2 4.5 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KEG10022.1 - 0.0013 18.4 5.1 0.0039 16.8 3.6 1.8 1 0 0 1 1 1 1 zinc-RING finger domain UEV PF05743.8 KEG10022.1 - 0.062 12.9 0.1 0.98 9.1 0.0 2.4 2 1 0 2 2 2 0 UEV domain GDPD PF03009.12 KEG10023.1 - 1.1e-33 116.8 0.0 4.6e-22 78.7 0.0 3.3 1 1 1 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family DDE_Tnp_1_6 PF13751.1 KEG10024.1 - 0.046 13.7 0.0 0.074 13.0 0.0 1.2 1 0 0 1 1 1 0 Transposase DDE domain Drf_FH1 PF06346.7 KEG10024.1 - 7.6 6.0 45.6 2.6 7.5 9.8 3.1 2 1 1 3 3 3 0 Formin Homology Region 1 Transposase_22 PF02994.9 KEG10025.1 - 0.14 10.6 0.0 0.14 10.6 0.0 3.4 4 0 0 4 4 4 0 L1 transposable element DUF3584 PF12128.3 KEG10025.1 - 4.2 4.5 56.9 0.47 7.7 2.6 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) Ribosomal_L21p PF00829.16 KEG10026.1 - 1.9e-20 72.8 0.1 2.9e-20 72.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Solute_trans_a PF03619.11 KEG10027.1 - 1e-70 238.1 20.9 1.1e-42 146.2 6.3 2.1 2 0 0 2 2 2 2 Organic solute transporter Ostalpha DUF1388 PF07142.7 KEG10027.1 - 0.79 9.4 2.7 1.3 8.8 1.9 1.3 1 0 0 1 1 1 0 Repeat of unknown function (DUF1388) Ras PF00071.17 KEG10028.1 - 4.1e-41 140.0 0.0 5.3e-41 139.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEG10028.1 - 1.6e-16 60.9 0.0 2.4e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEG10028.1 - 6e-09 35.3 0.0 8.8e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KEG10028.1 - 0.022 14.7 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF258 PF03193.11 KEG10028.1 - 0.088 11.9 0.0 0.23 10.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 MCM PF00493.18 KEG10028.1 - 0.12 11.1 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 MCM2/3/5 family Gtr1_RagA PF04670.7 KEG10028.1 - 0.17 10.9 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region IncA PF04156.9 KEG10032.1 - 0.87 9.1 5.5 0.31 10.6 1.3 1.9 2 0 0 2 2 2 0 IncA protein DUF2404 PF10296.4 KEG10035.1 - 6.8e-23 80.6 0.1 1.2e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) DUF2404 PF10296.4 KEG10036.1 - 1.7e-24 85.7 0.0 2.9e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) COQ9 PF08511.6 KEG10037.1 - 2.2e-06 27.0 0.0 8.2e-05 22.0 0.0 2.5 3 0 0 3 3 3 1 COQ9 DUF1496 PF07383.7 KEG10037.1 - 0.046 12.9 0.0 0.098 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1496) DUF202 PF02656.10 KEG10038.1 - 3.3e-17 62.4 1.2 1.1e-15 57.6 0.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) MscS_TM PF12794.2 KEG10038.1 - 0.053 12.1 1.2 0.066 11.8 0.8 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Abhydrolase_9_N PF15420.1 KEG10038.1 - 0.054 13.2 0.1 0.074 12.7 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus Clc-like PF07062.7 KEG10038.1 - 0.17 11.1 0.8 0.24 10.6 0.5 1.3 1 1 0 1 1 1 0 Clc-like Mito_carr PF00153.22 KEG10042.1 - 9.6e-14 50.8 2.0 2e-05 24.2 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.22 KEG10043.1 - 3.1e-31 106.9 1.3 8e-14 51.1 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein FANCI_S3 PF14677.1 KEG10046.1 - 0.025 13.9 0.1 0.081 12.2 0.0 1.7 2 0 0 2 2 2 0 FANCI solenoid 3 Pro_isomerase PF00160.16 KEG10047.1 - 1.2e-18 67.8 0.0 1.6e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TRAPP PF04051.11 KEG10048.1 - 7.8e-27 93.6 0.0 1.3e-26 92.9 0.0 1.4 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component MipZ PF09140.6 KEG10048.1 - 0.093 11.7 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 ATPase MipZ GTP_EFTU PF00009.22 KEG10049.1 - 2.6e-18 66.1 0.0 4.6e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KEG10049.1 - 0.0098 15.8 0.1 0.023 14.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KEG10049.1 - 0.051 13.1 0.3 0.14 11.6 0.2 1.8 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein IQ PF00612.22 KEG10050.1 - 5.6e-21 72.1 36.6 0.00025 20.3 0.5 7.9 7 0 0 7 7 7 6 IQ calmodulin-binding motif TPR_2 PF07719.12 KEG10050.1 - 0.064 13.2 2.9 1.6 8.8 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.20 KEG10051.1 - 1.7e-11 43.7 0.1 1.1e-09 37.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain F-box PF00646.28 KEG10051.1 - 0.0048 16.5 0.3 0.014 15.0 0.2 1.8 1 0 0 1 1 1 1 F-box domain FYVE_2 PF02318.11 KEG10051.1 - 1.3 8.9 6.0 3.9 7.3 4.2 1.9 1 0 0 1 1 1 0 FYVE-type zinc finger Hid1 PF12722.2 KEG10052.1 - 3.5e-38 130.9 0.0 2.8e-36 124.6 0.0 2.8 2 1 0 2 2 2 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 KEG10052.1 - 1.1e-23 83.3 0.1 2.7e-22 78.6 0.1 2.6 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein MotB_plug PF13677.1 KEG10052.1 - 0.0047 16.2 0.4 0.011 15.0 0.3 1.6 1 0 0 1 1 1 1 Membrane MotB of proton-channel complex MotA/MotB zf-C3HC4_3 PF13920.1 KEG10053.1 - 1.1e-08 34.5 6.4 1.1e-08 34.5 4.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEG10053.1 - 4.5e-07 29.4 9.4 4.5e-07 29.4 6.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KEG10053.1 - 6.5e-07 29.2 10.8 6.5e-07 29.2 7.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEG10053.1 - 2.9e-06 26.9 9.4 2.9e-06 26.9 6.5 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 KEG10053.1 - 3.2e-05 23.6 8.6 3.2e-05 23.6 6.0 2.9 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KEG10053.1 - 0.00018 21.0 8.6 0.00018 21.0 6.0 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KEG10053.1 - 0.0013 18.4 4.4 0.0026 17.4 3.1 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 KEG10053.1 - 0.0049 16.5 6.1 0.0049 16.5 4.3 2.5 1 1 1 2 2 2 1 RING-type zinc-finger DUF1272 PF06906.6 KEG10053.1 - 0.49 10.2 15.1 0.092 12.6 7.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DZR PF12773.2 KEG10053.1 - 0.6 9.9 18.6 9e+02 -0.2 12.8 3.1 1 1 0 1 1 1 0 Double zinc ribbon Prok-RING_4 PF14447.1 KEG10053.1 - 1.4 8.4 10.1 0.36 10.3 4.6 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-MIZ PF02891.15 KEG10053.1 - 6 6.4 9.6 31 4.1 6.7 2.1 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger SURF1 PF02104.10 KEG10055.1 - 1.4e-26 93.6 2.0 5.2e-26 91.8 0.0 2.2 2 1 0 2 2 2 1 SURF1 family IpaC_SipC PF09599.5 KEG10055.1 - 4.8 6.1 16.3 6.4 5.7 11.3 1.1 1 0 0 1 1 1 0 Salmonella-Shigella invasin protein C (IpaC_SipC) Herpes_BLRF2 PF05812.7 KEG10056.1 - 0.0034 17.1 0.3 0.0053 16.5 0.2 1.3 1 0 0 1 1 1 1 Herpesvirus BLRF2 protein Rootletin PF15035.1 KEG10056.1 - 0.013 15.5 3.0 0.02 14.8 1.9 1.5 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion F_actin_bind PF08919.5 KEG10056.1 - 0.014 15.0 0.1 0.023 14.3 0.1 1.6 1 1 0 1 1 1 0 F-actin binding Atg14 PF10186.4 KEG10056.1 - 0.024 13.5 2.5 0.028 13.3 1.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF724 PF05266.9 KEG10056.1 - 0.025 14.1 1.0 0.039 13.5 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) CCDC92 PF14916.1 KEG10056.1 - 0.037 13.6 4.5 0.74 9.4 0.0 3.0 2 1 0 2 2 2 0 Coiled-coil domain of unknown function DUF4201 PF13870.1 KEG10056.1 - 0.042 13.2 3.0 0.31 10.4 0.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF61 PF01886.11 KEG10056.1 - 0.057 13.2 0.3 0.11 12.3 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF61 bZIP_1 PF00170.16 KEG10056.1 - 0.061 13.2 2.8 0.061 13.2 1.9 2.4 2 1 0 2 2 2 0 bZIP transcription factor Mod_r PF07200.8 KEG10056.1 - 0.088 12.7 4.5 0.55 10.1 1.0 2.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Seadorna_VP6 PF07407.6 KEG10056.1 - 0.091 11.5 0.1 0.11 11.2 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein DUF972 PF06156.8 KEG10056.1 - 0.1 12.9 4.8 0.82 10.0 2.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Zein-binding PF04576.10 KEG10056.1 - 0.22 11.6 4.6 7.6 6.7 0.5 2.6 2 1 1 3 3 3 0 Zein-binding TSC22 PF01166.13 KEG10056.1 - 0.31 11.0 6.2 0.12 12.3 1.1 2.4 2 1 0 2 2 2 0 TSC-22/dip/bun family TMF_DNA_bd PF12329.3 KEG10056.1 - 0.31 10.8 4.9 0.89 9.4 2.0 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Kinetocho_Slk19 PF12709.2 KEG10056.1 - 0.44 10.6 4.4 0.32 11.0 0.9 2.1 2 1 0 2 2 2 0 Central kinetochore-associated Cep57_CLD_2 PF14197.1 KEG10056.1 - 0.44 10.5 7.3 3.3 7.7 2.2 2.9 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 ADIP PF11559.3 KEG10056.1 - 0.82 9.5 4.5 3.6 7.4 0.8 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DivIC PF04977.10 KEG10056.1 - 1 8.9 5.0 0.49 9.9 1.4 1.9 2 1 0 2 2 2 0 Septum formation initiator DUF904 PF06005.7 KEG10056.1 - 1.2 9.5 9.3 15 5.9 6.5 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF904) bZIP_2 PF07716.10 KEG10056.1 - 1.3 8.8 9.8 0.63 9.9 2.7 2.7 3 0 0 3 3 3 0 Basic region leucine zipper DivIVA PF05103.8 KEG10056.1 - 1.3 9.0 6.3 11 6.1 4.4 2.1 1 1 0 1 1 1 0 DivIVA protein IncA PF04156.9 KEG10056.1 - 3.6 7.1 7.4 13 5.3 5.1 1.8 1 1 0 1 1 1 0 IncA protein HALZ PF02183.13 KEG10056.1 - 6.7 6.5 9.2 0.34 10.6 1.4 2.4 4 0 0 4 4 3 0 Homeobox associated leucine zipper Kinesin PF00225.18 KEG10057.1 - 7.1e-86 287.9 0.0 8.9e-86 287.6 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain zf-TRAF PF02176.13 KEG10057.1 - 3.4e-16 59.3 47.8 5.6e-08 33.0 4.5 5.2 3 1 2 5 5 5 4 TRAF-type zinc finger zf-Di19 PF05605.7 KEG10057.1 - 0.00078 19.5 29.5 0.016 15.3 4.7 4.9 4 1 0 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding AAA_25 PF13481.1 KEG10057.1 - 0.015 14.7 0.0 0.032 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KEG10057.1 - 0.017 14.3 0.3 0.056 12.6 0.1 1.9 2 0 0 2 2 2 0 PhoH-like protein Peptidase_C2 PF00648.16 KEG10060.1 - 1.4e-24 86.6 0.0 2.6e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 KEG10060.1 - 7.5e-13 48.3 0.2 2.9e-08 33.4 0.0 3.4 3 0 0 3 3 3 2 Calpain large subunit, domain III MIT PF04212.13 KEG10060.1 - 0.0037 17.1 0.0 0.017 14.9 0.0 2.0 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_2 PF07719.12 KEG10060.1 - 0.022 14.6 0.1 0.79 9.7 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 KEG10060.1 - 0.031 14.0 0.1 10 6.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 KEG10060.1 - 0.036 14.7 0.1 19 6.0 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 KEG10060.1 - 0.045 13.6 0.0 9.8 6.2 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 KEG10060.1 - 0.17 11.5 0.1 0.58 9.8 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat PhyH PF05721.8 KEG10061.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) UAA PF08449.6 KEG10063.1 - 4.6e-46 157.1 9.3 8e-41 139.9 4.7 3.3 2 1 0 2 2 2 2 UAA transporter family EamA PF00892.15 KEG10063.1 - 0.05 13.6 11.9 0.18 11.8 2.7 2.9 2 0 0 2 2 2 0 EamA-like transporter family Nuc_sug_transp PF04142.10 KEG10063.1 - 0.29 10.2 3.0 0.39 9.7 0.0 2.5 3 0 0 3 3 3 0 Nucleotide-sugar transporter TPT PF03151.11 KEG10063.1 - 5.9 6.5 16.7 1.1 8.8 5.5 3.6 3 1 0 3 3 3 0 Triose-phosphate Transporter family RRM_5 PF13893.1 KEG10064.1 - 3.1e-05 23.7 0.0 0.091 12.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-U11-48K PF05253.7 KEG10064.1 - 0.00032 20.3 0.2 0.00059 19.4 0.2 1.5 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger Kelch_4 PF13418.1 KEG10065.1 - 1.4e-29 101.6 18.4 2e-08 33.8 0.3 6.7 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 KEG10065.1 - 1.6e-20 72.5 5.0 0.00011 22.0 0.0 6.2 6 1 0 6 6 6 4 Kelch motif Kelch_1 PF01344.20 KEG10065.1 - 6.7e-20 70.3 11.4 6.6e-06 25.5 0.1 7.0 7 0 0 7 7 7 3 Kelch motif Kelch_6 PF13964.1 KEG10065.1 - 3.4e-16 58.6 10.7 0.0022 18.0 0.0 6.8 7 1 0 7 7 7 4 Kelch motif Kelch_3 PF13415.1 KEG10065.1 - 3.7e-16 58.7 20.0 1.9e-07 31.0 0.0 7.6 8 0 0 8 8 8 4 Galactose oxidase, central domain Kelch_2 PF07646.10 KEG10065.1 - 4.4e-16 57.9 11.4 0.00012 21.6 0.2 5.8 5 0 0 5 5 5 4 Kelch motif BTB PF00651.26 KEG10065.1 - 1.9e-08 34.2 0.0 4.1e-05 23.5 0.0 3.3 2 2 0 2 2 2 2 BTB/POZ domain Birna_RdRp PF04197.7 KEG10066.1 - 0.21 9.5 10.1 0.34 8.9 7.0 1.3 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) MFS_1 PF07690.11 KEG10067.1 - 5.3e-32 110.9 57.1 1.7e-28 99.3 22.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEG10067.1 - 1.9e-20 72.8 28.0 2.6e-20 72.4 19.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 KEG10067.1 - 1.5e-09 36.4 16.9 2.4e-05 22.5 0.7 3.7 2 2 2 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.1 KEG10067.1 - 0.023 13.0 20.6 0.09 11.1 3.9 2.3 2 0 0 2 2 2 0 MFS/sugar transport protein CybS PF05328.7 KEG10067.1 - 0.079 12.5 0.8 0.34 10.5 0.0 2.4 3 0 0 3 3 3 0 CybS FtsJ PF01728.14 KEG10071.1 - 5.7e-42 143.7 0.4 6.9e-42 143.4 0.3 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Pkinase PF00069.20 KEG10072.1 - 3e-07 29.8 0.0 5.1e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain C2 PF00168.25 KEG10074.1 - 7.9e-22 76.9 0.1 1.4e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 C2 domain CEP76-C2 PF15627.1 KEG10074.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 CEP76 C2 domain PAT1 PF09770.4 KEG10074.1 - 3 5.9 54.5 3.6 5.7 37.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Herpes_U5 PF05999.6 KEG10076.1 - 0.079 11.5 0.1 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus U5-like family PQQ_2 PF13360.1 KEG10077.1 - 0.029 13.8 0.7 0.15 11.4 0.0 2.2 2 0 0 2 2 2 0 PQQ-like domain OMS28_porin PF03532.8 KEG10077.1 - 0.39 9.7 1.6 0.71 8.9 1.1 1.3 1 0 0 1 1 1 0 OMS28 porin Myc_N PF01056.13 KEG10077.1 - 0.69 9.0 6.2 1.2 8.2 4.3 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Pribosyltran_N PF13793.1 KEG10078.1 - 1.2e-36 124.9 0.1 7e-34 116.0 0.0 2.3 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KEG10078.1 - 7.3e-22 78.0 0.2 8.1e-21 74.5 0.0 2.2 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KEG10078.1 - 4.8e-10 39.2 0.9 2.5e-09 36.8 0.4 2.3 2 1 0 2 2 2 1 Phosphoribosyl transferase domain DUF1126 PF06565.7 KEG10079.1 - 2.5e-30 103.6 0.4 7.9e-12 44.4 0.0 3.5 3 0 0 3 3 3 3 Repeat of unknown function (DUF1126) EF-hand_6 PF13405.1 KEG10079.1 - 9e-07 28.2 0.1 0.00042 19.9 0.2 3.6 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 KEG10079.1 - 3.7e-06 25.8 1.0 5.5e-05 22.1 0.3 2.7 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 KEG10079.1 - 4.2e-05 23.6 0.2 0.0021 18.1 0.1 3.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.1 KEG10079.1 - 0.0002 20.9 0.2 0.036 13.6 0.2 3.2 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.1 KEG10079.1 - 0.0038 16.4 0.3 0.01 15.1 0.2 1.8 1 0 0 1 1 1 1 EF hand TPR_11 PF13414.1 KEG10080.1 - 4.8e-64 211.9 43.0 7.1e-18 64.0 2.6 6.2 6 0 0 6 6 6 6 TPR repeat TPR_1 PF00515.23 KEG10080.1 - 1.2e-44 148.1 43.1 3.5e-08 32.7 0.3 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 KEG10080.1 - 7.2e-40 131.7 47.3 3.4e-05 23.4 0.3 9.5 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_16 PF13432.1 KEG10080.1 - 7.7e-22 77.4 28.1 4.3e-07 30.4 0.4 6.6 5 1 2 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.1 KEG10080.1 - 1.8e-18 66.2 36.7 1.1e-06 28.5 1.3 6.6 3 3 3 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 KEG10080.1 - 2e-17 62.0 24.8 0.029 15.0 0.0 9.9 3 3 7 10 10 10 6 Tetratricopeptide repeat TPR_19 PF14559.1 KEG10080.1 - 2.4e-17 63.0 17.1 0.00042 20.6 0.2 6.6 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 KEG10080.1 - 6.1e-16 56.9 32.5 0.003 17.2 0.5 8.7 7 2 2 9 9 9 5 Tetratricopeptide repeat Apc3 PF12895.2 KEG10080.1 - 5.2e-14 52.1 31.8 1.9e-07 31.1 5.2 4.8 3 1 1 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KEG10080.1 - 8.8e-12 44.7 13.2 2.8e-05 23.8 0.1 6.4 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 KEG10080.1 - 6.4e-11 41.5 23.7 0.013 15.6 0.1 8.9 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.1 KEG10080.1 - 2e-09 36.5 24.2 0.36 10.7 0.1 8.7 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_6 PF13174.1 KEG10080.1 - 0.00011 22.4 22.5 2.5 8.7 0.0 7.8 7 0 0 7 7 7 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KEG10080.1 - 0.00015 21.5 18.0 0.042 13.7 0.1 7.5 8 0 0 8 8 8 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 KEG10080.1 - 0.0016 18.2 29.5 1.4 8.9 0.3 7.6 9 0 0 9 9 9 2 Tetratricopeptide repeat DUF3856 PF12968.2 KEG10080.1 - 0.0038 17.0 14.9 0.5 10.1 0.4 5.2 3 3 1 4 4 4 2 Domain of Unknown Function (DUF3856) FadA PF09403.5 KEG10080.1 - 0.085 12.8 19.1 0.3 11.1 1.6 3.7 2 1 1 3 3 3 0 Adhesion protein FadA TPR_20 PF14561.1 KEG10080.1 - 0.2 11.7 12.8 1.1 9.4 0.2 4.6 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_21 PF09976.4 KEG10080.1 - 3.3 7.6 21.5 3.7 7.4 1.4 5.0 3 2 1 4 4 4 0 Tetratricopeptide repeat DUF2666 PF10869.3 KEG10081.1 - 0.3 11.1 3.5 0.56 10.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2666) DUF1993 PF09351.5 KEG10081.1 - 0.34 10.8 3.0 0.5 10.2 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1993) SnAC PF14619.1 KEG10081.1 - 3 8.0 7.1 0.31 11.2 0.8 2.5 3 0 0 3 3 3 0 Snf2-ATP coupling, chromatin remodelling complex tRNA-synt_2d PF01409.15 KEG10083.1 - 1.3e-81 273.4 0.2 2e-81 272.8 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 KEG10083.1 - 3.9e-06 25.8 0.8 4.7e-05 22.3 0.2 2.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 KEG10083.1 - 0.003 17.1 0.5 0.003 17.1 0.3 1.9 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) MarR_2 PF12802.2 KEG10083.1 - 0.021 14.5 0.0 0.22 11.2 0.0 2.6 3 0 0 3 3 3 0 MarR family MarR PF01047.17 KEG10083.1 - 0.044 13.5 0.0 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 MarR family TrmB PF01978.14 KEG10083.1 - 0.13 11.9 0.0 9.4 6.0 0.0 2.8 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB RasGAP PF00616.14 KEG10084.1 - 8.4e-10 38.6 0.0 9.2e-09 35.2 0.0 2.1 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RRM_6 PF14259.1 KEG10086.1 - 1.5e-18 66.5 0.0 5.6e-06 26.2 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEG10086.1 - 7e-16 57.6 0.0 0.0011 18.5 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG10086.1 - 5e-15 55.0 0.0 8.6e-07 28.7 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAT1 PF09770.4 KEG10086.1 - 4.2 5.4 6.3 6 4.9 4.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RRM_5 PF13893.1 KEG10087.1 - 1.6e-12 47.1 0.4 6.9e-06 25.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG10087.1 - 5.9e-07 29.3 0.7 0.15 12.0 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEG10087.1 - 4.5e-06 26.2 0.0 0.11 12.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cyclin PF08613.6 KEG10088.1 - 2.7e-28 99.2 0.2 3.8e-28 98.7 0.1 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KEG10088.1 - 2e-11 43.5 0.8 3.8e-11 42.6 0.1 1.8 2 1 0 2 2 2 1 Cyclin, N-terminal domain HSP70 PF00012.15 KEG10091.1 - 3.6e-40 137.4 14.4 4.3e-38 130.6 0.0 3.9 3 1 1 4 4 4 3 Hsp70 protein CDC45 PF02724.9 KEG10091.1 - 2.2 6.1 13.0 4 5.3 9.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Ycf1 PF05758.7 KEG10091.1 - 5 4.7 7.3 6.7 4.2 5.0 1.1 1 0 0 1 1 1 0 Ycf1 Peptidase_M16 PF00675.15 KEG10092.1 - 1.4e-44 151.4 0.2 9.2e-44 148.8 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KEG10092.1 - 1.4e-22 80.2 0.0 3.8e-19 69.0 0.0 2.2 2 0 0 2 2 2 2 Peptidase M16 inactive domain ORC2 PF04084.9 KEG10093.1 - 0.34 9.6 0.0 5.9 5.6 0.0 2.1 2 0 0 2 2 2 0 Origin recognition complex subunit 2 ADH_zinc_N PF00107.21 KEG10095.1 - 1.5e-20 73.0 0.0 2.5e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEG10095.1 - 8.7e-13 47.9 0.0 3.7e-12 45.9 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KEG10095.1 - 6.6e-11 43.2 0.0 1.4e-10 42.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase LRR_6 PF13516.1 KEG10096.1 - 2.1e-38 126.0 50.6 0.012 15.6 0.3 21.9 22 0 0 22 22 22 13 Leucine Rich repeat LRR_4 PF12799.2 KEG10096.1 - 1e-17 63.2 43.2 0.0009 18.8 0.3 13.5 10 4 6 16 16 16 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG10096.1 - 2.8e-10 39.7 33.5 0.14 11.9 1.7 12.6 9 4 4 13 13 13 7 Leucine rich repeat LRR_1 PF00560.28 KEG10096.1 - 1.7e-09 36.4 33.4 9.1 6.7 0.2 16.6 21 0 0 21 21 21 2 Leucine Rich Repeat XPC-binding PF09280.6 KEG10096.1 - 0.00084 18.7 0.4 12 5.4 0.0 4.1 4 0 0 4 4 4 2 XPC-binding domain LRR_7 PF13504.1 KEG10096.1 - 1.9 9.0 25.4 81 4.1 0.3 11.9 14 0 0 14 14 14 0 Leucine rich repeat T2SI PF02501.12 KEG10097.1 - 0.0014 18.5 1.1 0.59 10.1 0.0 3.4 2 0 0 2 2 2 2 Type II secretion system (T2SS), protein I DUF2730 PF10805.3 KEG10097.1 - 0.0074 16.0 2.9 0.0074 16.0 2.0 4.3 4 0 0 4 4 4 2 Protein of unknown function (DUF2730) FlaC_arch PF05377.6 KEG10097.1 - 0.15 11.9 7.4 6.5 6.7 0.2 3.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) WD40 PF00400.27 KEG10098.1 - 8.9e-12 44.4 5.6 0.00035 20.3 0.0 5.5 5 1 0 5 5 5 3 WD domain, G-beta repeat PQQ_3 PF13570.1 KEG10098.1 - 0.046 14.0 0.2 2.4 8.5 0.1 3.1 2 0 0 2 2 2 0 PQQ-like domain Pkinase PF00069.20 KEG10099.1 - 1e-46 159.2 0.0 1.4e-46 158.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG10099.1 - 8.3e-16 57.8 0.0 1.2e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEG10099.1 - 0.00011 21.9 0.1 0.099 12.3 0.0 2.2 1 1 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KEG10099.1 - 0.069 12.2 0.1 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HECT PF00632.20 KEG10101.1 - 1e-43 149.6 0.0 1.8e-43 148.8 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) PAT1 PF09770.4 KEG10101.1 - 3.7 5.6 0.0 6.3 4.9 0.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 His_Phos_2 PF00328.17 KEG10103.1 - 0.00015 21.2 0.1 0.00038 19.8 0.0 1.7 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 2) ParA PF10609.4 KEG10104.1 - 3.4e-36 122.9 0.1 6.1e-36 122.1 0.1 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KEG10104.1 - 2.2e-17 63.1 0.1 2.9e-17 62.7 0.1 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 KEG10104.1 - 3.3e-08 32.9 1.5 2.1e-07 30.3 1.0 1.9 1 1 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.1 KEG10104.1 - 1.8e-05 24.7 0.0 7e-05 22.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 KEG10104.1 - 8.2e-05 21.7 2.2 0.00033 19.7 0.4 2.3 2 1 1 3 3 3 1 Anion-transporting ATPase Fer4_NifH PF00142.13 KEG10104.1 - 0.00013 21.2 0.0 0.0028 16.9 0.1 2.1 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.6 KEG10104.1 - 0.00052 19.1 0.1 0.00095 18.3 0.1 1.4 1 0 0 1 1 1 1 VirC1 protein YhjQ PF06564.7 KEG10104.1 - 0.045 13.1 0.2 0.069 12.5 0.1 1.5 1 1 0 1 1 1 0 YhjQ protein VCBS PF13517.1 KEG10105.1 - 9.3e-14 51.5 4.1 0.058 13.7 0.1 5.4 5 0 0 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 KEG10105.1 - 2.8e-07 30.0 16.9 0.071 12.8 0.2 6.2 6 0 0 6 6 6 3 FG-GAP repeat TcdB_toxin_midN PF12256.3 KEG10105.1 - 0.00075 18.9 3.9 0.52 9.7 0.2 3.6 3 1 1 4 4 4 2 Insecticide toxin TcdB middle/N-terminal region EF-hand_5 PF13202.1 KEG10105.1 - 0.00097 18.3 2.1 2.8 7.4 0.1 3.7 3 0 0 3 3 3 2 EF hand EF-hand_1 PF00036.27 KEG10105.1 - 0.16 11.3 3.8 23 4.5 0.0 3.6 3 0 0 3 3 3 0 EF hand DUF676 PF05057.9 KEG10106.1 - 6.6e-13 48.4 0.0 1.4e-12 47.3 0.0 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.10 KEG10106.1 - 0.0029 16.6 0.0 0.0049 15.8 0.0 1.6 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF900 PF05990.7 KEG10106.1 - 0.0084 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.8 KEG10106.1 - 0.057 12.9 0.1 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein Hexapep PF00132.19 KEG10107.1 - 4.5e-07 29.0 19.5 1.3e-05 24.4 2.3 3.2 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 KEG10107.1 - 7.3e-05 22.1 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 KEG10107.1 - 0.0041 17.2 0.0 0.01 15.9 0.0 1.7 1 1 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 KEG10107.1 - 0.021 14.3 7.1 0.031 13.8 2.4 2.9 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase DUF1093 PF06486.6 KEG10107.1 - 0.12 12.7 0.2 0.21 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1093) ATP-synt_ab PF00006.20 KEG10108.1 - 1.8e-62 210.6 0.0 2.4e-62 210.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KEG10108.1 - 2.4e-14 53.7 0.0 5.4e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KEG10108.1 - 1.7e-12 47.3 0.5 3.4e-12 46.3 0.4 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Glyco_transf_25 PF01755.12 KEG10109.1 - 1.6e-10 41.0 0.0 8.1e-07 28.8 0.0 2.1 1 1 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Snf7 PF03357.16 KEG10110.1 - 3.6e-27 94.8 27.0 3.6e-27 94.8 18.7 1.2 1 1 0 1 1 1 1 Snf7 DUF768 PF05589.6 KEG10110.1 - 0.0079 16.1 0.3 0.022 14.7 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF768) KTI12 PF08433.5 KEG10110.1 - 7.4 5.6 12.1 0.24 10.5 0.4 2.2 1 1 0 2 2 2 0 Chromatin associated protein KTI12 Metal_resist PF13801.1 KEG10110.1 - 8 6.4 17.7 0.27 11.2 5.0 2.8 3 0 0 3 3 3 0 Heavy-metal resistance CRAL_TRIO PF00650.15 KEG10111.1 - 4.7e-26 91.1 0.0 8.3e-26 90.3 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KEG10111.1 - 0.0021 18.1 0.0 0.005 16.9 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KEG10111.1 - 0.11 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Vps26 PF03643.10 KEG10112.1 - 1e-59 201.6 0.1 1.2e-59 201.3 0.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 KEG10112.1 - 5.9e-07 29.4 0.6 0.0067 16.2 0.1 3.3 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain adh_short PF00106.20 KEG10113.1 - 5.8e-29 101.1 0.3 8.5e-29 100.6 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEG10113.1 - 9.6e-14 51.4 0.6 3.6e-13 49.5 0.4 1.9 1 1 0 1 1 1 1 KR domain Pyr_redox PF00070.22 KEG10113.1 - 1.5e-05 25.2 0.5 3e-05 24.3 0.3 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.1 KEG10113.1 - 0.00027 20.9 0.0 0.00071 19.6 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 KEG10113.1 - 0.00034 20.4 0.0 0.00048 19.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 KEG10113.1 - 0.0012 18.5 0.2 0.0019 17.8 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 KEG10113.1 - 0.0027 17.6 0.0 1.1 9.0 0.3 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Polysacc_synt_2 PF02719.10 KEG10113.1 - 0.0044 15.9 0.0 0.0054 15.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KEG10113.1 - 0.015 14.7 0.1 0.037 13.4 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ApbA PF02558.11 KEG10113.1 - 0.022 14.2 0.1 0.039 13.3 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 KEG10113.1 - 0.047 12.8 0.0 0.075 12.1 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 KEG10113.1 - 0.052 12.5 0.6 0.083 11.9 0.4 1.2 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 KEG10113.1 - 0.17 10.7 0.9 0.24 10.1 0.7 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Ribosomal_L29e PF01779.12 KEG10114.1 - 1.6e-17 63.0 5.3 1.6e-17 63.0 3.7 1.7 2 1 0 2 2 2 1 Ribosomal L29e protein family HTH_Tnp_Mu_2 PF09039.6 KEG10114.1 - 0.039 13.6 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 Mu DNA binding, I gamma subdomain IGF2_C PF08365.6 KEG10114.1 - 8.9 6.1 7.5 2.7 7.8 0.3 2.4 2 1 1 3 3 3 0 Insulin-like growth factor II E-peptide Ribosomal_L29e PF01779.12 KEG10115.1 - 8e-18 64.0 5.3 1.6e-17 63.0 3.7 1.5 1 0 0 1 1 1 1 Ribosomal L29e protein family HTH_Tnp_Mu_2 PF09039.6 KEG10115.1 - 0.051 13.3 0.0 0.073 12.8 0.0 1.2 1 0 0 1 1 1 0 Mu DNA binding, I gamma subdomain DUF904 PF06005.7 KEG10118.1 - 0.014 15.6 0.5 0.034 14.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF904) BASP1 PF05466.7 KEG10118.1 - 0.039 13.7 1.6 0.061 13.1 1.1 1.2 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) Rab5-bind PF09311.6 KEG10118.1 - 0.093 12.6 5.5 0.8 9.5 0.4 2.7 2 1 0 2 2 2 0 Rabaptin-like protein HALZ PF02183.13 KEG10118.1 - 0.12 12.1 1.3 4 7.2 0.2 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper BPL_LplA_LipB PF03099.14 KEG10119.1 - 2.5e-16 59.7 0.0 3.1e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family HTH_32 PF13565.1 KEG10120.1 - 0.084 13.6 0.0 0.22 12.3 0.0 1.7 1 1 0 1 1 1 0 Homeodomain-like domain Bromodomain PF00439.20 KEG10121.1 - 2e-15 56.4 0.0 4.2e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Bromodomain DUF3708 PF12501.3 KEG10121.1 - 0.11 12.2 0.1 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter DUF1657 PF07870.6 KEG10121.1 - 0.16 11.6 1.0 1.8 8.3 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1657) RRM_1 PF00076.17 KEG10123.1 - 9.3e-15 54.0 0.1 2.1e-07 30.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG10123.1 - 1.1e-12 47.6 0.0 1.6e-07 31.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF4651 PF15513.1 KEG10123.1 - 0.0048 16.3 0.0 3.3 7.2 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4651) DUF853 PF05872.7 KEG10123.1 - 0.01 14.2 0.3 0.012 13.9 0.2 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) RRM_5 PF13893.1 KEG10123.1 - 0.017 14.9 0.0 0.09 12.6 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KEG10123.1 - 0.026 14.2 0.1 0.06 13.1 0.1 1.6 1 0 0 1 1 1 0 Limkain b1 DUF4448 PF14610.1 KEG10123.1 - 0.065 12.7 0.2 0.093 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DNA_ligase_IV PF11411.3 KEG10123.1 - 0.15 11.8 3.4 1.5 8.6 0.0 3.0 3 0 0 3 3 3 0 DNA ligase IV Paramyxo_ncap PF00973.14 KEG10123.1 - 0.47 9.0 2.0 0.52 8.9 1.4 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein XAP5 PF04921.9 KEG10123.1 - 1.3 8.5 6.9 1.8 8.0 4.8 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator Glyco_transf_22 PF03901.12 KEG10124.1 - 3e-26 92.3 19.1 4.7e-26 91.7 13.2 1.3 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Mid2 PF04478.7 KEG10124.1 - 0.054 12.9 3.6 0.064 12.6 1.4 1.8 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Ribosomal_L11_N PF03946.9 KEG10125.1 - 1.6e-13 49.8 0.0 2.7e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 KEG10125.1 - 2.8e-05 24.1 0.0 6.3e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Lipase_GDSL_2 PF13472.1 KEG10127.1 - 6.5e-24 85.0 0.0 8.2e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KEG10127.1 - 4.1e-17 62.7 0.0 5.8e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DZR PF12773.2 KEG10128.1 - 1.3e-07 31.2 70.9 0.001 18.8 6.2 7.8 5 1 4 9 9 9 7 Double zinc ribbon TrmB PF01978.14 KEG10128.1 - 0.066 12.9 0.0 0.57 9.9 0.0 2.3 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Speriolin_N PF15058.1 KEG10129.1 - 0.012 15.5 1.5 0.012 15.5 1.0 1.2 1 0 0 1 1 1 0 Speriolin N terminus Atg14 PF10186.4 KEG10130.1 - 7e-09 35.0 0.0 1.3e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 OstA PF03968.9 KEG10130.1 - 0.017 15.0 1.1 0.034 14.0 0.8 1.4 1 0 0 1 1 1 0 OstA-like protein APG6 PF04111.7 KEG10130.1 - 0.02 13.9 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Spc7 PF08317.6 KEG10130.1 - 0.49 9.0 6.1 0.66 8.5 4.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein MalF_P2 PF14785.1 KEG10130.1 - 0.66 9.8 3.2 1.5 8.6 2.2 1.6 1 0 0 1 1 1 0 Maltose transport system permease protein MalF P2 domain HlyD PF00529.15 KEG10130.1 - 4.1 6.6 18.2 6.1 6.0 12.6 1.2 1 0 0 1 1 1 0 HlyD family secretion protein EMG1 PF03587.9 KEG10131.1 - 6.9e-05 22.2 0.0 7.5e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Peptidase_M22 PF00814.20 KEG10133.1 - 5.8e-85 285.0 0.0 7e-85 284.7 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family CmcH_NodU PF02543.10 KEG10133.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase VCBS PF13517.1 KEG10136.1 - 3.8e-14 52.7 14.4 0.00029 21.1 4.1 6.2 4 2 2 6 6 6 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 KEG10136.1 - 1.7e-10 40.2 23.4 0.01 15.4 2.0 6.3 6 0 0 6 6 6 4 FG-GAP repeat PQQ_2 PF13360.1 KEG10136.1 - 3.4e-06 26.6 0.2 0.0029 17.0 0.0 2.9 2 1 1 3 3 3 2 PQQ-like domain TcdB_toxin_midN PF12256.3 KEG10136.1 - 0.0021 17.5 4.6 1.1 8.6 0.1 4.9 4 1 1 5 5 5 1 Insecticide toxin TcdB middle/N-terminal region PQQ PF01011.16 KEG10136.1 - 0.008 15.6 0.1 16 5.2 0.0 4.2 4 0 0 4 4 4 1 PQQ enzyme repeat BBS2_C PF14782.1 KEG10136.1 - 0.19 10.2 0.0 0.99 7.8 0.0 2.0 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal Dus PF01207.12 KEG10137.1 - 5.6e-49 166.6 0.0 8e-49 166.1 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) BT1 PF03092.11 KEG10138.1 - 1.5e-141 472.0 9.8 1.8e-141 471.8 6.8 1.0 1 0 0 1 1 1 1 BT1 family dCMP_cyt_deam_1 PF00383.17 KEG10139.1 - 2.4e-12 46.3 2.6 3.5e-12 45.8 1.8 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 KEG10139.1 - 7.8e-07 29.1 0.3 6.8e-06 26.1 0.1 2.1 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region DUF406 PF04175.7 KEG10139.1 - 0.019 15.4 0.4 6.2 7.3 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF406) LmjF365940-deam PF14421.1 KEG10139.1 - 0.12 11.6 0.4 0.24 10.7 0.3 1.6 1 1 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases Acetyltransf_9 PF13527.1 KEG10141.1 - 0.033 14.0 0.0 0.04 13.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Spc7 PF08317.6 KEG10141.1 - 0.079 11.6 1.5 0.095 11.3 1.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Pinin_SDK_memA PF04696.8 KEG10141.1 - 0.37 10.3 4.2 0.46 10.0 2.9 1.1 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region IncA PF04156.9 KEG10141.1 - 0.47 10.0 4.2 0.6 9.6 2.9 1.1 1 0 0 1 1 1 0 IncA protein DUF3595 PF12166.3 KEG10142.1 - 1.3e-36 126.3 0.1 1.6e-36 126.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3595) BTB PF00651.26 KEG10142.1 - 0.057 13.4 0.2 0.12 12.3 0.1 1.6 1 1 0 1 1 1 0 BTB/POZ domain HCV_NS2 PF01538.13 KEG10142.1 - 0.093 12.1 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS2 DNA_pol_A PF00476.15 KEG10143.1 - 1.3e-68 231.4 0.0 2.7e-65 220.4 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family A Macoilin PF09726.4 KEG10143.1 - 8.1 4.5 11.5 12 4.0 8.0 1.1 1 0 0 1 1 1 0 Transmembrane protein DnaJ PF00226.26 KEG10146.1 - 4.7e-12 45.4 0.1 1.1e-11 44.2 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain Orexin PF02072.10 KEG10146.1 - 0.66 9.7 3.2 0.44 10.3 0.3 1.9 1 1 1 2 2 2 0 Prepro-orexin ADIP PF11559.3 KEG10147.1 - 2.2e-05 24.3 6.1 0.0016 18.3 1.2 2.1 2 0 0 2 2 2 2 Afadin- and alpha -actinin-Binding DUF2360 PF10152.4 KEG10147.1 - 0.0075 16.5 2.5 0.039 14.2 1.7 2.0 1 1 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) CENP-F_leu_zip PF10473.4 KEG10147.1 - 0.017 15.0 10.7 0.13 12.1 1.4 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 KEG10147.1 - 0.035 13.7 8.2 0.85 9.1 0.6 2.1 2 0 0 2 2 2 0 IncA protein Zwint PF15556.1 KEG10147.1 - 0.038 13.2 4.9 0.11 11.6 3.4 1.7 1 1 0 1 1 1 0 ZW10 interactor DUF4279 PF14106.1 KEG10147.1 - 0.074 12.9 1.0 0.25 11.2 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) ATG16 PF08614.6 KEG10147.1 - 0.075 12.8 11.3 0.5 10.1 1.3 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DASH_Spc19 PF08287.6 KEG10147.1 - 0.086 12.4 3.7 0.16 11.6 2.5 1.5 1 0 0 1 1 1 0 Spc19 Med9 PF07544.8 KEG10147.1 - 0.09 12.5 0.2 0.09 12.5 0.1 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 CASP_C PF08172.7 KEG10147.1 - 0.11 11.5 4.5 0.15 11.0 3.1 1.2 1 0 0 1 1 1 0 CASP C terminal FliJ PF02050.11 KEG10147.1 - 0.11 12.5 4.5 0.34 10.9 1.1 2.2 1 1 1 2 2 2 0 Flagellar FliJ protein Prefoldin PF02996.12 KEG10147.1 - 0.12 11.9 7.0 2 8.0 0.3 2.5 2 1 0 2 2 2 0 Prefoldin subunit FlgN PF05130.7 KEG10147.1 - 0.13 12.4 8.1 0.2 11.8 5.6 1.3 1 0 0 1 1 1 0 FlgN protein K-box PF01486.12 KEG10147.1 - 0.21 11.3 8.6 0.37 10.6 1.8 2.3 2 0 0 2 2 2 0 K-box region Prefoldin_2 PF01920.15 KEG10147.1 - 0.27 10.9 9.0 0.44 10.3 0.5 2.4 2 0 0 2 2 2 0 Prefoldin subunit DUF4201 PF13870.1 KEG10147.1 - 0.66 9.3 10.2 0.83 9.0 2.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) EzrA PF06160.7 KEG10147.1 - 0.72 7.9 6.0 0.09 10.9 0.5 1.8 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Uds1 PF15456.1 KEG10147.1 - 0.77 9.7 7.9 2.3 8.2 1.6 2.2 1 1 1 2 2 2 0 Up-regulated During Septation TPR_MLP1_2 PF07926.7 KEG10147.1 - 0.91 9.2 11.3 1.8 8.3 1.8 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein UPF0184 PF03670.8 KEG10147.1 - 0.96 9.6 4.1 3 8.0 0.1 2.7 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0184) DUF4200 PF13863.1 KEG10147.1 - 0.96 9.4 10.6 0.75 9.7 0.7 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) DUF972 PF06156.8 KEG10147.1 - 0.98 9.7 7.2 5.3 7.4 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Sec8_exocyst PF04048.9 KEG10147.1 - 1.1 8.9 5.1 0.31 10.6 0.9 1.8 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain ERM PF00769.14 KEG10147.1 - 3.6 7.0 10.4 3.7 7.0 1.3 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF4140 PF13600.1 KEG10147.1 - 6.6 7.2 6.7 12 6.4 0.5 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Snapin_Pallidin PF14712.1 KEG10147.1 - 8.6 6.7 7.6 13 6.1 1.1 2.7 2 1 0 2 2 2 0 Snapin/Pallidin TSC22 PF01166.13 KEG10148.1 - 0.64 10.0 8.2 0.8 9.7 0.1 3.6 3 0 0 3 3 3 0 TSC-22/dip/bun family Exo_endo_phos PF03372.18 KEG10149.1 - 9.3e-19 68.3 0.1 1.7e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DnaJ PF00226.26 KEG10150.1 - 5.5e-09 35.6 0.0 1.2e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain WASH-7_mid PF14744.1 KEG10151.1 - 5.3e-152 505.7 0.3 8.8e-152 504.9 0.2 1.4 1 0 0 1 1 1 1 WASH complex subunit 7 WASH-7_N PF14745.1 KEG10151.1 - 2.8e-149 497.9 0.6 4.8e-149 497.1 0.4 1.4 1 0 0 1 1 1 1 WASH complex subunit 7, N-terminal WASH-7_C PF14746.1 KEG10151.1 - 4.2e-60 202.1 0.5 1.2e-59 200.6 0.3 1.9 1 0 0 1 1 1 1 WASH complex subunit 7, C-terminal GKAP PF03359.8 KEG10151.1 - 0.0083 15.7 0.1 0.0083 15.7 0.1 2.4 3 0 0 3 3 3 1 Guanylate-kinase-associated protein (GKAP) protein Serine_rich PF08824.5 KEG10151.1 - 0.016 14.9 0.2 0.11 12.1 0.0 2.4 2 0 0 2 2 2 0 Serine rich protein interaction domain TPR_12 PF13424.1 KEG10152.1 - 3e-22 78.3 10.6 5.3e-10 39.0 1.0 4.1 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 KEG10152.1 - 3.1e-09 36.3 3.9 0.00012 21.6 0.4 4.3 3 1 1 4 4 4 2 TPR repeat TPR_2 PF07719.12 KEG10152.1 - 3.7e-09 35.8 8.0 0.18 11.7 0.0 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 KEG10152.1 - 7.3e-06 25.4 2.3 3.8 7.5 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEG10152.1 - 3.3e-05 24.1 9.0 0.3 11.8 0.0 6.1 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.1 KEG10152.1 - 4.1e-05 23.3 17.6 0.31 11.0 0.1 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_21 PF09976.4 KEG10152.1 - 9.5e-05 22.3 0.2 0.37 10.7 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 KEG10152.1 - 0.00011 21.6 1.9 1.5 8.5 0.0 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 KEG10152.1 - 0.001 19.1 1.4 0.055 13.6 0.0 3.4 2 2 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 KEG10152.1 - 0.024 15.2 13.3 4.5 8.0 0.2 5.0 4 1 0 4 4 4 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 KEG10152.1 - 0.028 13.6 1.4 2.6 7.3 0.0 3.6 3 0 0 3 3 3 0 SHNi-TPR RPN7 PF10602.4 KEG10152.1 - 0.074 12.4 4.0 20 4.4 0.0 4.3 3 1 1 5 5 5 0 26S proteasome subunit RPN7 TPR_19 PF14559.1 KEG10152.1 - 0.37 11.1 8.2 1.4 9.3 0.1 4.6 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 KEG10153.1 - 3.5e-05 23.6 7.7 0.00077 19.3 1.3 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEG10153.1 - 0.00022 20.9 3.3 0.39 10.7 0.0 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEG10153.1 - 0.0023 18.2 4.0 0.0029 17.9 1.2 2.2 2 1 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 KEG10153.1 - 0.0043 17.1 3.7 0.034 14.2 0.7 2.2 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 KEG10153.1 - 0.009 16.6 3.1 0.07 13.8 0.5 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 KEG10153.1 - 0.037 14.4 0.8 0.16 12.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KEG10153.1 - 0.089 12.6 0.1 12 5.8 0.0 2.5 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.1 KEG10153.1 - 0.11 13.2 5.8 0.68 10.7 0.2 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 KEG10153.1 - 0.69 10.5 0.2 0.69 10.5 0.1 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat Opiods_neuropep PF01160.13 KEG10153.1 - 2 8.2 4.5 6.2 6.6 0.1 3.2 3 0 0 3 3 3 0 Vertebrate endogenous opioids neuropeptide DUF2312 PF10073.4 KEG10154.1 - 0.14 11.5 0.1 0.27 10.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) DUF3505 PF12013.3 KEG10154.1 - 0.26 11.5 5.7 3.1 8.0 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3505) DUF4505 PF14956.1 KEG10155.1 - 3.9e-17 62.4 0.0 3.8e-11 42.9 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4505) Amastin PF07344.6 KEG10156.1 - 4e-34 117.4 9.4 5.5e-34 117.0 6.5 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein PMP22_Claudin PF00822.15 KEG10156.1 - 0.0002 21.0 10.1 0.00024 20.7 7.0 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KEG10156.1 - 0.017 14.7 11.9 0.023 14.4 7.9 1.6 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF2721 PF11026.3 KEG10156.1 - 0.58 9.7 14.3 0.071 12.7 6.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) Kinesin PF00225.18 KEG10157.1 - 2.8e-94 315.5 0.6 5.4e-94 314.6 0.1 1.7 2 0 0 2 2 2 1 Kinesin motor domain K_channel_TID PF07941.6 KEG10158.1 - 0.55 10.5 8.0 1.4 9.2 5.6 1.7 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain OmpH PF03938.9 KEG10158.1 - 0.98 9.3 9.0 1.5 8.7 6.2 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Mnd1 PF03962.10 KEG10158.1 - 3 7.4 11.0 1.9 8.1 6.4 1.5 1 1 1 2 2 2 0 Mnd1 family RNF111_N PF15303.1 KEG10158.1 - 9.1 5.7 12.7 1e+02 2.3 2.7 2.1 1 1 1 2 2 2 0 E3 ubiquitin-protein ligase Arkadia N-terminus BSD PF03909.12 KEG10159.1 - 8.8e-10 38.1 0.0 2e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 BSD domain PepSY_2 PF13670.1 KEG10159.1 - 0.028 14.3 3.8 0.071 13.0 2.6 1.6 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain PHD_2 PF13831.1 KEG10160.1 - 0.023 13.9 1.9 0.044 13.1 1.3 1.4 1 0 0 1 1 1 0 PHD-finger Thymidylate_kin PF02223.12 KEG10161.1 - 1.1e-16 60.7 0.0 1.3e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_16 PF13191.1 KEG10161.1 - 0.00058 19.8 0.5 0.021 14.7 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 KEG10161.1 - 0.00093 19.0 0.3 0.0022 17.8 0.2 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KEG10161.1 - 0.0069 16.6 0.3 0.038 14.2 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEG10161.1 - 0.0097 16.7 0.0 0.017 15.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KEG10161.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KEG10161.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 RNA helicase Glyco_transf_11 PF01531.11 KEG10162.1 - 2.4e-13 49.7 0.4 3.6e-07 29.4 0.0 2.9 3 0 0 3 3 3 2 Glycosyl transferase family 11 Glutaredoxin PF00462.19 KEG10163.1 - 1.4e-18 66.6 0.1 4.9e-18 64.8 0.1 1.9 2 0 0 2 2 2 1 Glutaredoxin TarH PF02203.10 KEG10164.1 - 0.046 13.5 0.9 0.083 12.7 0.6 1.3 1 0 0 1 1 1 0 Tar ligand binding domain homologue UBA PF00627.26 KEG10166.1 - 1.3e-07 31.2 0.3 1.3e-07 31.2 0.2 2.4 3 0 0 3 3 3 1 UBA/TS-N domain ubiquitin PF00240.18 KEG10166.1 - 2.8e-05 23.4 0.0 4.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family CUE PF02845.11 KEG10166.1 - 0.021 14.3 0.8 1.7 8.2 0.1 2.8 2 0 0 2 2 2 0 CUE domain Rad60-SLD_2 PF13881.1 KEG10166.1 - 0.096 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Pkinase PF00069.20 KEG10167.1 - 1.1e-78 263.9 0.0 1.3e-78 263.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG10167.1 - 4.7e-36 124.1 0.0 1.1e-35 123.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KEG10167.1 - 0.0013 18.5 0.4 0.006 16.3 0.1 2.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KEG10167.1 - 0.036 13.0 0.0 3 6.7 0.0 2.2 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.17 KEG10167.1 - 0.052 12.9 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family DUF1192 PF06698.6 KEG10168.1 - 0.037 13.8 14.2 0.18 11.6 0.0 4.4 3 1 1 4 4 4 0 Protein of unknown function (DUF1192) YABBY PF04690.8 KEG10168.1 - 0.51 10.5 4.3 0.42 10.8 2.0 1.6 1 1 0 1 1 1 0 YABBY protein Orbi_VP5 PF00901.12 KEG10168.1 - 0.66 8.1 12.1 0.6 8.2 7.6 1.4 1 1 0 1 1 1 0 Orbivirus outer capsid protein VP5 M_domain PF12938.2 KEG10168.1 - 1.8 8.2 10.0 18 5.0 0.0 2.6 1 1 1 2 2 2 0 M domain of GW182 DUF1640 PF07798.6 KEG10168.1 - 2.1 8.3 14.4 0.81 9.7 7.6 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) HalX PF08663.5 KEG10168.1 - 3 7.8 8.9 16 5.5 0.0 4.1 3 2 2 5 5 5 0 HalX domain ACCA PF03255.9 KEG10168.1 - 4.8 6.7 12.4 1.7 8.1 2.4 3.1 2 1 1 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit CALCOCO1 PF07888.6 KEG10168.1 - 5.4 5.1 20.6 0.99 7.6 10.8 1.8 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like PBP_sp32 PF07222.7 KEG10168.1 - 5.6 6.0 8.5 1.8 7.7 3.8 1.8 1 1 1 2 2 2 0 Proacrosin binding protein sp32 GTP_EFTU PF00009.22 KEG10169.1 - 6.9e-59 198.4 0.0 1.2e-58 197.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 KEG10169.1 - 9e-26 89.5 0.0 2.8e-25 87.9 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 KEG10169.1 - 1.4e-20 72.9 0.0 3e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.13 KEG10169.1 - 2e-14 53.1 0.0 4.8e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.20 KEG10169.1 - 7.2e-07 29.2 0.2 3.3e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KEG10169.1 - 0.0052 16.7 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 KEG10169.1 - 0.068 12.2 0.0 0.17 11.0 0.0 1.6 1 0 0 1 1 1 0 AIG1 family CRAL_TRIO PF00650.15 KEG10170.1 - 1.9e-21 76.2 0.0 2.7e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CAP_GLY PF01302.20 KEG10170.1 - 2.8e-11 42.9 0.1 4.7e-11 42.2 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain CRAL_TRIO_2 PF13716.1 KEG10170.1 - 0.013 15.4 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain IF4E PF01652.13 KEG10171.1 - 7.7e-09 35.2 0.0 9.3e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Ribosomal_S27 PF01599.14 KEG10172.1 - 7e-20 70.5 3.0 1.6e-19 69.4 2.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.18 KEG10172.1 - 2.2e-05 23.7 2.0 0.0012 18.2 0.0 3.1 2 1 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 KEG10172.1 - 4e-05 23.2 0.0 0.0016 18.0 0.0 2.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.16 KEG10172.1 - 0.0023 17.7 0.3 0.0047 16.7 0.2 1.5 1 0 0 1 1 1 1 IBR domain TrkA_N PF02254.13 KEG10173.1 - 7.6e-05 22.6 0.1 0.00022 21.2 0.0 1.9 2 0 0 2 2 2 1 TrkA-N domain F420_oxidored PF03807.12 KEG10173.1 - 0.00026 21.3 0.0 0.00065 20.0 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ATG27 PF09451.5 KEG10173.1 - 0.032 13.4 0.0 0.059 12.5 0.0 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 NAD_binding_7 PF13241.1 KEG10173.1 - 0.043 14.0 0.0 0.15 12.3 0.0 1.9 1 0 0 1 1 1 0 Putative NAD(P)-binding Saccharop_dh PF03435.13 KEG10173.1 - 0.059 12.3 0.3 0.11 11.5 0.2 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KEG10173.1 - 0.13 12.4 0.1 0.32 11.0 0.0 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase CENP-B_dimeris PF09026.5 KEG10173.1 - 0.14 12.4 5.6 0.4 10.9 3.9 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4484 PF14831.1 KEG10173.1 - 1.6 8.8 4.8 32 4.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) DUF2457 PF10446.4 KEG10173.1 - 1.6 7.3 16.2 1.6 7.3 7.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Nucleoplasmin PF03066.10 KEG10173.1 - 10 5.6 8.0 33 3.9 5.4 2.0 2 0 0 2 2 2 0 Nucleoplasmin SYCE1 PF15233.1 KEG10174.1 - 0.022 14.6 0.2 0.022 14.6 0.1 2.8 2 2 1 3 3 3 0 Synaptonemal complex central element protein 1 Reo_sigmaC PF04582.7 KEG10174.1 - 0.041 13.0 0.8 0.58 9.2 0.0 2.5 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Syntaxin PF00804.20 KEG10174.1 - 0.16 12.1 8.7 0.98 9.6 0.3 3.5 3 0 0 3 3 3 0 Syntaxin DUF2203 PF09969.4 KEG10174.1 - 0.16 12.1 9.7 0.3 11.3 0.1 3.6 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2203) Sec8_exocyst PF04048.9 KEG10174.1 - 0.34 10.5 6.3 20 4.8 0.1 4.4 3 2 1 5 5 5 0 Sec8 exocyst complex component specific domain Nup35_RRM_2 PF14605.1 KEG10176.1 - 7.2e-17 60.9 0.0 1.4e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-RING_UBOX PF13445.1 KEG10177.1 - 0.00045 19.8 1.2 0.00045 19.8 0.8 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KEG10177.1 - 0.0005 19.8 2.4 0.0005 19.8 1.7 2.7 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KEG10177.1 - 0.00071 19.1 3.0 0.00071 19.1 2.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEG10177.1 - 0.0016 18.4 5.4 0.0016 18.4 3.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEG10177.1 - 0.0051 16.6 10.6 0.033 14.0 5.0 2.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KEG10177.1 - 0.011 15.5 5.9 0.011 15.5 4.1 2.5 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_6 PF14835.1 KEG10177.1 - 0.042 13.6 8.6 0.076 12.8 3.6 2.5 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Hox9_act PF04617.8 KEG10178.1 - 0.093 12.8 1.4 0.1 12.7 0.9 1.1 1 0 0 1 1 1 0 Hox9 activation region Ribosomal_S13_N PF08069.7 KEG10181.1 - 6.9e-26 89.8 1.3 9.5e-26 89.4 0.2 1.8 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 KEG10181.1 - 1.1e-23 82.7 0.3 1.4e-23 82.4 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S15 Synaptobrevin PF00957.16 KEG10182.1 - 1.3e-12 47.1 0.0 3.4e-12 45.7 0.0 1.7 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.1 KEG10182.1 - 0.0018 17.7 0.0 0.014 14.9 0.0 2.3 2 0 0 2 2 2 1 Regulated-SNARE-like domain DUF2570 PF10828.3 KEG10182.1 - 0.072 12.7 0.5 0.19 11.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) UMP1 PF05348.6 KEG10183.1 - 0.069 13.1 0.0 0.091 12.7 0.0 1.1 1 0 0 1 1 1 0 Proteasome maturation factor UMP1 TFIIS_C PF01096.13 KEG10184.1 - 4.8e-16 58.1 3.1 4.8e-16 58.1 2.1 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KEG10184.1 - 1.6e-05 24.4 3.5 1.7e-05 24.3 0.4 2.4 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit TF_Zn_Ribbon PF08271.7 KEG10184.1 - 8.4e-05 21.8 2.9 0.0071 15.6 1.1 2.9 3 1 0 3 3 3 1 TFIIB zinc-binding DNA_ligase_ZBD PF03119.11 KEG10184.1 - 0.11 12.2 3.9 11 5.8 0.0 3.0 2 1 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain DZR PF12773.2 KEG10184.1 - 0.17 11.7 0.3 0.17 11.7 0.2 2.5 2 1 0 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.1 KEG10184.1 - 0.19 10.9 0.4 0.19 10.9 0.3 3.4 3 0 0 3 3 3 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 KEG10184.1 - 0.6 9.8 5.8 4.5 7.0 0.2 2.6 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.2 KEG10184.1 - 0.67 9.8 7.5 1.4 8.7 1.0 2.7 2 2 0 2 2 2 0 Transposase zinc-ribbon domain Baculo_LEF5_C PF11792.3 KEG10184.1 - 0.95 8.9 4.9 0.19 11.1 0.6 2.1 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain zf-Mss51 PF13824.1 KEG10184.1 - 1.6 8.6 5.9 12 5.8 0.2 2.6 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Nudix_N_2 PF14803.1 KEG10184.1 - 3.3 7.4 8.8 1.8 8.3 2.7 2.8 2 1 0 2 2 2 0 Nudix N-terminal IBR PF01485.16 KEG10184.1 - 4.8 7.1 7.7 3.4 7.6 0.2 2.7 2 1 0 2 2 2 0 IBR domain DUF2296 PF10058.4 KEG10184.1 - 4.9 6.9 7.5 26 4.6 0.0 3.2 2 1 1 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) Zn-ribbon_8 PF09723.5 KEG10184.1 - 6.3 6.8 7.1 78 3.3 0.1 3.8 3 1 1 4 4 4 0 Zinc ribbon domain CNH PF00780.17 KEG10185.1 - 0.00011 21.7 0.0 0.00023 20.6 0.0 1.5 1 0 0 1 1 1 1 CNH domain Ank_5 PF13857.1 KEG10185.1 - 0.06 13.6 0.7 5.1 7.4 0.1 2.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) DUF4217 PF13959.1 KEG10186.1 - 0.048 13.1 0.2 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4217) NAP PF00956.13 KEG10187.1 - 2.2e-61 207.0 0.0 2.2e-61 207.0 0.0 1.8 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Nucleoplasmin PF03066.10 KEG10187.1 - 0.002 17.6 16.9 0.026 14.0 2.0 2.5 2 0 0 2 2 2 2 Nucleoplasmin Daxx PF03344.10 KEG10187.1 - 0.045 12.2 12.0 0.096 11.1 8.3 1.5 1 0 0 1 1 1 0 Daxx Family DUF4576 PF15144.1 KEG10187.1 - 0.17 11.5 1.6 0.5 10.0 1.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) PBP1_TM PF14812.1 KEG10187.1 - 0.4 11.0 26.3 0.11 12.8 2.5 3.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.1 KEG10187.1 - 0.72 10.0 18.1 0.7 10.0 3.7 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) BUD22 PF09073.5 KEG10187.1 - 0.78 8.7 13.1 1.5 7.7 9.1 1.4 1 0 0 1 1 1 0 BUD22 Senescence_reg PF04520.8 KEG10187.1 - 2.3 8.7 8.6 0.27 11.7 0.1 2.8 3 0 0 3 3 3 0 Senescence regulator DUF2457 PF10446.4 KEG10187.1 - 2.4 6.7 21.0 0.016 13.9 2.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) CENP-B_dimeris PF09026.5 KEG10187.1 - 4.4 7.6 32.0 0.58 10.4 6.4 3.0 3 0 0 3 3 3 0 Centromere protein B dimerisation domain YL1 PF05764.8 KEG10187.1 - 7.3 6.1 17.1 0.58 9.7 8.0 1.9 2 0 0 2 2 2 0 YL1 nuclear protein TT_ORF2 PF02957.10 KEG10188.1 - 0.16 12.6 3.2 0.32 11.6 0.0 2.9 3 0 0 3 3 3 0 TT viral ORF2 DUF2360 PF10152.4 KEG10189.1 - 2.9e-25 89.2 0.2 3.8e-25 88.9 0.1 1.2 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) Dict-STAT-coil PF09267.5 KEG10189.1 - 0.13 12.4 0.1 0.19 11.9 0.1 1.2 1 0 0 1 1 1 0 Dictyostelium STAT, coiled coil SlyX PF04102.7 KEG10189.1 - 0.43 10.9 0.0 0.43 10.9 0.0 2.3 4 0 0 4 4 4 0 SlyX Synaptobrevin PF00957.16 KEG10190.1 - 6e-30 102.7 0.5 2.3e-29 100.8 0.1 2.0 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.1 KEG10190.1 - 1.5e-17 62.8 0.3 2.5e-17 62.2 0.2 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain RPW8 PF05659.6 KEG10190.1 - 0.055 13.0 0.3 0.15 11.6 0.1 1.8 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Fzo_mitofusin PF04799.8 KEG10190.1 - 0.15 11.3 0.9 0.37 10.1 0.6 1.8 1 1 0 1 1 1 0 fzo-like conserved region DUF1301 PF06979.7 KEG10192.1 - 0.067 13.3 0.0 0.09 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1301) YesK PF14150.1 KEG10193.1 - 0.11 12.6 1.8 0.21 11.7 1.3 1.5 1 0 0 1 1 1 0 YesK-like protein TPR_11 PF13414.1 KEG10194.1 - 2.3e-18 65.6 4.6 5.6e-13 48.3 0.1 3.3 2 1 1 3 3 3 2 TPR repeat RPAP3_C PF13877.1 KEG10194.1 - 7.6e-18 64.2 0.3 1.6e-17 63.2 0.0 1.7 2 0 0 2 2 1 1 Potential Monad-binding region of RPAP3 TPR_1 PF00515.23 KEG10194.1 - 2.6e-12 45.7 5.3 0.0089 15.6 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEG10194.1 - 4.6e-11 41.7 8.5 0.00024 20.7 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 KEG10194.1 - 1.2e-06 28.9 11.4 0.0024 18.4 0.1 3.7 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 KEG10194.1 - 2.4e-05 24.1 11.9 8.8e-05 22.2 0.3 4.9 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 KEG10194.1 - 0.0001 22.6 6.2 0.022 15.3 0.1 4.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEG10194.1 - 0.0018 17.9 2.5 5.2 7.0 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 KEG10194.1 - 0.0036 17.3 0.0 0.014 15.5 0.0 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF3808 PF10300.4 KEG10194.1 - 0.0057 15.2 0.1 0.0057 15.2 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_12 PF13424.1 KEG10194.1 - 0.0067 16.3 0.4 0.0067 16.3 0.3 3.2 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_3 PF07720.7 KEG10194.1 - 0.023 14.4 0.2 0.089 12.6 0.0 2.1 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_19 PF14559.1 KEG10194.1 - 0.053 13.8 6.1 0.82 10.0 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEG10194.1 - 0.055 13.9 4.7 0.47 11.0 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 KEG10194.1 - 0.055 13.6 2.2 19 5.7 0.0 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KEG10194.1 - 0.068 12.9 1.6 19 5.3 0.1 3.4 3 0 0 3 3 2 0 Tetratricopeptide repeat Sen15 PF09631.5 KEG10194.1 - 0.16 12.2 1.1 1.3 9.3 0.0 2.7 2 1 0 2 2 2 0 Sen15 protein Cwf_Cwc_15 PF04889.7 KEG10194.1 - 0.2 11.3 24.4 0.016 14.9 10.1 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF4654 PF15547.1 KEG10194.1 - 0.38 11.0 0.1 0.38 11.0 0.0 2.2 3 1 0 3 3 2 0 Domain of unknown function (DUF4654) LIX1 PF14954.1 KEG10194.1 - 0.6 9.0 6.6 0.94 8.3 4.2 1.6 1 1 0 1 1 1 0 Limb expression 1 Spt5_N PF11942.3 KEG10194.1 - 1 9.9 18.7 0.15 12.7 8.7 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Pex19 PF04614.7 KEG10194.1 - 4.3 6.8 20.2 4.8 6.7 0.6 2.3 2 0 0 2 2 2 0 Pex19 protein family DnaJ PF00226.26 KEG10195.1 - 1.3e-27 95.2 0.8 2e-27 94.6 0.6 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KEG10195.1 - 2.9e-21 75.1 0.9 3e-17 62.3 0.0 2.9 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KEG10195.1 - 7.6e-14 51.5 14.8 1.3e-13 50.8 10.3 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 KEG10195.1 - 0.0075 15.9 5.2 0.1 12.3 0.6 2.4 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family Thyroglobulin_1 PF00086.13 KEG10195.1 - 0.2 11.0 4.6 0.59 9.5 0.0 2.6 2 0 0 2 2 2 0 Thyroglobulin type-1 repeat DZR PF12773.2 KEG10195.1 - 6.7 6.6 11.0 74 3.2 7.6 2.3 1 1 0 1 1 1 0 Double zinc ribbon Aldo_ket_red PF00248.16 KEG10196.1 - 1.4e-44 152.0 0.0 1.7e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family TBPIP PF07106.8 KEG10197.1 - 4.1e-21 75.2 0.6 4.9e-21 75.0 0.4 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Penicillinase_R PF03965.11 KEG10197.1 - 0.0021 18.1 0.7 0.017 15.1 0.1 2.4 2 1 1 3 3 3 1 Penicillinase repressor Golgin_A5 PF09787.4 KEG10197.1 - 0.0058 15.2 3.2 0.007 14.9 2.2 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 TMF_TATA_bd PF12325.3 KEG10197.1 - 0.018 14.7 2.7 0.03 14.0 0.7 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF2529 PF10740.4 KEG10197.1 - 0.04 13.3 0.8 0.27 10.6 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2529) Mnd1 PF03962.10 KEG10197.1 - 0.046 13.3 3.6 0.083 12.5 2.5 1.6 1 1 0 1 1 1 0 Mnd1 family SR-25 PF10500.4 KEG10197.1 - 0.16 11.3 3.7 0.23 10.9 2.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TPR_MLP1_2 PF07926.7 KEG10197.1 - 0.24 11.1 7.0 0.09 12.5 2.8 1.8 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein HAUS6_N PF14661.1 KEG10197.1 - 0.62 9.3 5.9 1.2 8.4 4.1 1.4 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Seryl_tRNA_N PF02403.17 KEG10197.1 - 0.67 9.9 7.1 0.15 12.0 2.2 1.9 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain adh_short PF00106.20 KEG10199.1 - 3.3e-27 95.4 2.9 5e-27 94.8 2.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEG10199.1 - 3.3e-18 66.3 0.0 8.2e-18 65.0 0.0 1.4 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEG10199.1 - 7.4e-16 58.3 2.5 1.9e-15 56.9 1.7 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KEG10199.1 - 5.5e-07 29.2 0.5 3.8e-06 26.4 0.4 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEG10199.1 - 0.0038 17.2 0.1 0.0072 16.3 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KEG10199.1 - 0.012 14.4 0.1 4.4 6.1 0.0 2.6 1 1 1 2 2 2 0 Male sterility protein RmlD_sub_bind PF04321.12 KEG10199.1 - 0.016 14.0 0.2 0.025 13.4 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain CM2 PF03021.9 KEG10200.1 - 0.013 15.0 0.1 0.46 10.0 0.1 2.2 2 0 0 2 2 2 0 Influenza C virus M2 protein Utp12 PF04003.7 KEG10200.1 - 0.02 14.7 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 Dip2/Utp12 Family Kinesin PF00225.18 KEG10203.1 - 2.5e-95 319.0 0.0 4.1e-95 318.3 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Seryl_tRNA_N PF02403.17 KEG10203.1 - 0.14 12.2 6.1 0.64 10.0 0.4 3.0 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TK PF00265.13 KEG10204.1 - 1.9e-07 30.8 0.5 3e-07 30.1 0.3 1.4 1 0 0 1 1 1 1 Thymidine kinase EF_TS PF00889.14 KEG10204.1 - 0.081 12.2 2.1 0.22 10.8 0.1 1.9 2 0 0 2 2 2 0 Elongation factor TS TK PF00265.13 KEG10205.1 - 5.2e-17 61.9 0.0 6.3e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Thymidine kinase HTH_1 PF00126.22 KEG10207.1 - 0.0092 15.7 2.7 0.52 10.0 0.3 3.4 3 0 0 3 3 3 1 Bacterial regulatory helix-turn-helix protein, lysR family LRR_6 PF13516.1 KEG10208.1 - 3e-14 51.4 30.2 0.054 13.5 0.0 11.1 11 0 0 11 11 11 5 Leucine Rich repeat LRR_4 PF12799.2 KEG10208.1 - 3.6e-05 23.2 29.6 0.31 10.7 0.5 8.6 7 2 1 9 9 9 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEG10208.1 - 0.00027 20.5 22.0 33 5.0 0.0 10.6 12 0 0 12 12 12 0 Leucine Rich Repeat CARD PF00619.16 KEG10208.1 - 0.057 13.2 1.6 1.7 8.5 0.0 3.0 2 0 0 2 2 2 0 Caspase recruitment domain LRR_8 PF13855.1 KEG10208.1 - 0.42 10.3 28.6 1.3 8.8 0.5 7.2 6 2 1 7 7 7 0 Leucine rich repeat Vfa1 PF08432.5 KEG10208.1 - 2 8.4 14.7 3.9 7.4 10.2 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Hid1 PF12722.2 KEG10208.1 - 2.4 5.7 3.9 3.4 5.2 2.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Aldo_ket_red PF00248.16 KEG10209.1 - 7.8e-61 205.3 0.0 9.2e-61 205.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_transf_15 PF01793.11 KEG10210.1 - 5.7e-12 45.2 0.8 7.6e-12 44.8 0.5 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ribosomal_S5_C PF03719.10 KEG10211.1 - 1.4e-23 81.9 0.0 2.3e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 KEG10211.1 - 2.5e-21 75.1 0.7 3.9e-21 74.5 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain FoP_duplication PF13865.1 KEG10211.1 - 0.84 10.1 6.2 1.8 9.0 4.3 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Gly-rich_Ago1 PF12764.2 KEG10211.1 - 3 8.5 8.3 6.5 7.4 5.8 1.6 1 0 0 1 1 1 0 Glycine-rich region of argonaut SNARE PF05739.14 KEG10213.1 - 2.5e-07 30.2 4.0 2.5e-07 30.2 2.8 2.4 2 0 0 2 2 2 1 SNARE domain Baculo_PEP_C PF04513.7 KEG10213.1 - 0.005 16.6 0.8 0.005 16.6 0.6 1.7 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin PF00804.20 KEG10213.1 - 0.011 15.8 5.2 0.37 10.9 0.4 2.6 2 0 0 2 2 2 0 Syntaxin EMP24_GP25L PF01105.19 KEG10213.1 - 0.027 14.1 0.5 0.027 14.1 0.3 2.1 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD AAA_13 PF13166.1 KEG10213.1 - 0.17 10.3 6.4 0.37 9.1 0.2 2.0 2 0 0 2 2 2 0 AAA domain WXG100 PF06013.7 KEG10213.1 - 1.3 9.0 8.3 1.5 8.8 2.5 2.5 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Brix PF04427.13 KEG10214.1 - 2.6e-35 121.8 0.0 3.6e-35 121.3 0.0 1.2 1 0 0 1 1 1 1 Brix domain Rtf2 PF04641.7 KEG10217.1 - 1.4e-21 76.9 0.0 2.2e-21 76.2 0.0 1.3 1 1 0 1 1 1 1 Rtf2 RING-finger zf-RING_5 PF14634.1 KEG10217.1 - 0.036 13.7 0.2 0.099 12.3 0.2 1.8 1 1 0 1 1 1 0 zinc-RING finger domain zf-Nse PF11789.3 KEG10217.1 - 0.046 13.2 0.4 1.6 8.3 0.0 2.8 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.1 KEG10217.1 - 0.064 12.9 0.5 0.29 10.8 0.4 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 KEG10217.1 - 0.084 12.4 1.7 2.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 EF-hand_1 PF00036.27 KEG10218.1 - 0.0022 17.1 0.0 0.98 8.8 0.0 2.9 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 KEG10218.1 - 0.018 15.1 0.4 0.094 12.8 0.1 2.3 2 0 0 2 2 2 0 EF-hand domain pair Asp_protease PF09668.5 KEG10219.1 - 4.2e-52 174.9 0.8 6.1e-52 174.3 0.6 1.2 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 KEG10219.1 - 1.2e-08 35.3 0.0 2.7e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease UBA_4 PF14555.1 KEG10219.1 - 1.1e-07 31.2 0.1 2.3e-07 30.2 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain gag-asp_proteas PF13975.1 KEG10219.1 - 1.9e-06 27.5 0.0 5.2e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 KEG10219.1 - 0.0001 22.2 0.0 0.00022 21.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 KEG10219.1 - 0.0004 20.2 0.0 0.00094 19.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease UBA PF00627.26 KEG10219.1 - 0.00078 19.2 0.2 0.002 17.8 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain ubiquitin PF00240.18 KEG10219.1 - 0.0028 17.0 0.0 0.0067 15.8 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family DUF1631 PF07793.6 KEG10219.1 - 0.015 13.4 5.3 0.025 12.7 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) DUF3391 PF11871.3 KEG10219.1 - 0.058 13.6 1.7 0.13 12.5 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) PAT1 PF09770.4 KEG10219.1 - 0.069 11.3 17.9 0.085 11.0 12.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4175 PF13779.1 KEG10219.1 - 4.3 4.9 17.8 5.3 4.6 12.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Suf PF05843.9 KEG10219.1 - 4.9 6.8 6.6 6.9 6.3 4.6 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pex14_N PF04695.8 KEG10219.1 - 5 7.1 12.0 0.59 10.1 5.0 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region BAF1_ABF1 PF04684.8 KEG10219.1 - 9.9 4.8 11.7 14 4.3 8.1 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RabGAP-TBC PF00566.13 KEG10220.1 - 1.4e-33 116.1 0.0 2.2e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RNA_ligase PF09414.5 KEG10221.1 - 1.6e-52 178.0 0.0 2.4e-52 177.4 0.0 1.3 1 0 0 1 1 1 1 RNA ligase DNA_ligase_A_M PF01068.16 KEG10221.1 - 0.039 13.3 0.0 0.082 12.2 0.0 1.5 1 0 0 1 1 1 0 ATP dependent DNA ligase domain PHBC_N PF12551.3 KEG10222.1 - 0.019 14.4 0.1 0.05 13.1 0.0 1.7 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase N terminal Cas_Cmr3 PF09700.5 KEG10222.1 - 0.051 12.9 0.0 3.2 7.0 0.0 2.2 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cmr3) Mtc PF03820.12 KEG10223.1 - 2.3e-92 308.9 0.0 2.6e-92 308.7 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier PRP3 PF08572.5 KEG10224.1 - 4.3e-45 153.8 2.4 4.6e-45 153.7 0.6 1.7 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 KEG10224.1 - 3.6e-24 84.8 0.0 7.4e-24 83.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) PEARLI-4 PF05278.7 KEG10224.1 - 0.18 11.1 1.4 0.24 10.7 0.1 1.7 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) Y_phosphatase3C PF13348.1 KEG10226.1 - 0.066 13.3 0.0 0.36 10.9 0.0 2.1 2 0 0 2 2 2 0 Tyrosine phosphatase family C-terminal region cNMP_binding PF00027.24 KEG10228.1 - 5.4e-13 48.5 0.0 2e-07 30.7 0.0 3.6 3 1 0 3 3 3 3 Cyclic nucleotide-binding domain DNA_primase_S PF01896.14 KEG10229.1 - 6.7e-38 129.7 0.0 1.1e-37 129.0 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit DUF342 PF03961.8 KEG10233.1 - 0.2 10.0 1.6 0.31 9.4 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) MTBP_C PF14920.1 KEG10233.1 - 0.21 11.0 4.2 0.1 12.0 0.2 1.9 1 1 1 2 2 2 0 MDM2-binding DASH_Dad3 PF08656.5 KEG10233.1 - 0.53 10.0 0.1 0.53 10.0 0.1 3.0 3 1 1 4 4 4 0 DASH complex subunit Dad3 DUF1515 PF07439.6 KEG10233.1 - 0.79 9.5 4.6 1.6 8.5 3.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) APG6 PF04111.7 KEG10233.1 - 1.2 8.0 12.2 1.9 7.4 8.4 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF940 PF06082.6 KEG10233.1 - 1.4 7.4 5.5 1.6 7.1 3.8 1.0 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) V_ATPase_I PF01496.14 KEG10233.1 - 2 6.1 4.5 2.3 5.9 3.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HlyD PF00529.15 KEG10233.1 - 2.8 7.1 16.6 3.4 6.8 11.5 1.2 1 0 0 1 1 1 0 HlyD family secretion protein Spc24 PF08286.6 KEG10233.1 - 8.9 6.0 11.8 8.4 6.1 2.7 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF3653 PF12375.3 KEG10233.1 - 9.6 6.4 7.1 1.2 9.3 0.4 2.4 1 1 1 2 2 2 0 Phage protein THF_DHG_CYH_C PF02882.14 KEG10234.1 - 2.3e-38 130.8 2.1 1.2e-37 128.4 1.4 2.1 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 KEG10234.1 - 5.7e-27 94.0 0.0 8.7e-27 93.4 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain DUF793 PF05633.6 KEG10234.1 - 0.028 13.1 0.2 0.045 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF793) Peptidase_M8 PF01457.11 KEG10236.1 - 8.9e-99 331.1 2.8 2.9e-50 171.0 0.5 2.0 2 0 0 2 2 2 2 Leishmanolysin Reprolysin_5 PF13688.1 KEG10236.1 - 0.0003 20.7 0.0 0.00065 19.6 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M57 PF12388.3 KEG10236.1 - 0.0028 17.0 0.0 0.019 14.3 0.0 2.0 2 0 0 2 2 2 1 Dual-action HEIGH metallo-peptidase Reprolysin_3 PF13582.1 KEG10236.1 - 0.015 15.7 0.1 0.029 14.8 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KEG10236.1 - 0.028 14.1 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 Matrixin Peptidase_M8 PF01457.11 KEG10237.1 - 2.7e-27 95.3 0.0 3.2e-27 95.0 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin DPPIV_N PF00930.16 KEG10237.1 - 0.15 10.6 0.0 0.2 10.2 0.0 1.2 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_M8 PF01457.11 KEG10238.1 - 1.5e-63 214.9 4.9 6.2e-58 196.4 2.4 2.1 1 1 1 2 2 2 2 Leishmanolysin HAD_2 PF13419.1 KEG10240.1 - 0.83 9.8 5.5 1.2 9.3 0.0 3.0 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Kinesin PF00225.18 KEG10245.1 - 0.019 13.7 5.2 0.022 13.4 0.1 3.3 4 0 0 4 4 4 0 Kinesin motor domain rve PF00665.21 KEG10247.1 - 0.069 13.2 0.0 4.4 7.4 0.0 2.3 2 0 0 2 2 2 0 Integrase core domain DUF1190 PF06693.6 KEG10249.1 - 0.98 9.4 4.1 2.3 8.2 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1190) FYVE PF01363.16 KEG10250.1 - 0.0091 15.8 15.1 0.077 12.8 10.5 2.2 1 1 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 KEG10250.1 - 0.069 13.0 8.7 0.14 12.0 6.0 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger zf-C2HC_2 PF13913.1 KEG10250.1 - 0.27 10.9 0.3 0.27 10.9 0.2 3.4 3 1 1 4 4 4 0 zinc-finger of a C2HC-type vMSA PF00695.14 KEG10250.1 - 5.7 6.0 5.5 8.6 5.4 3.8 1.3 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus EF-hand_6 PF13405.1 KEG10251.1 - 2.2e-09 36.3 0.1 1.4e-05 24.6 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 KEG10251.1 - 1.2e-08 34.9 1.2 0.00026 21.0 0.1 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KEG10251.1 - 1.4e-07 31.0 4.5 0.00026 20.5 0.2 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 KEG10251.1 - 6.4e-07 28.2 0.3 1.1e-05 24.4 0.0 2.7 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.1 KEG10251.1 - 1.9e-06 26.9 0.1 5.2e-06 25.5 0.0 1.9 2 0 0 2 2 2 1 EF hand DUF3008 PF11450.3 KEG10251.1 - 0.051 13.7 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknwon function (DUF3008) DUF3349 PF11829.3 KEG10251.1 - 0.12 12.7 0.4 1.8 9.0 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3349) Ribosomal_L6e PF01159.14 KEG10251.1 - 0.12 12.5 0.5 0.45 10.7 0.1 1.9 1 1 1 2 2 2 0 Ribosomal protein L6e Peptidase_S9 PF00326.16 KEG10252.1 - 2.4e-33 115.1 0.1 6.8e-33 113.6 0.1 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family DPPIV_N PF00930.16 KEG10252.1 - 1.1e-30 106.4 0.0 1.8e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Abhydrolase_5 PF12695.2 KEG10252.1 - 7.1e-07 29.0 0.1 2e-06 27.6 0.1 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KEG10252.1 - 0.018 14.2 0.7 0.043 13.0 0.5 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_6 PF12697.2 KEG10252.1 - 0.028 14.2 0.2 0.092 12.6 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF2007 PF09413.5 KEG10252.1 - 0.054 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2007) LIP PF03583.9 KEG10252.1 - 0.093 11.9 0.3 0.59 9.2 0.1 2.0 1 1 0 2 2 2 0 Secretory lipase Cullin_Nedd8 PF10557.4 KEG10253.1 - 1.1e-19 70.0 0.2 2.1e-19 69.0 0.1 1.5 1 0 0 1 1 1 1 Cullin protein neddylation domain Cullin PF00888.17 KEG10253.1 - 1.9e-05 23.4 0.0 3.3e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Cullin family TrbL PF04610.9 KEG10253.1 - 0.34 10.5 0.0 0.96 9.1 0.0 1.7 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein EF-hand_8 PF13833.1 KEG10254.1 - 0.016 14.7 0.1 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_7 PF13499.1 KEG10254.1 - 0.031 14.4 0.0 0.19 11.8 0.0 1.8 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.27 KEG10254.1 - 0.13 11.6 0.8 0.24 10.8 0.1 1.8 2 0 0 2 2 2 0 EF hand Radial_spoke PF04712.7 KEG10255.1 - 2.4e-128 428.9 0.0 3.2e-128 428.5 0.0 1.0 1 0 0 1 1 1 1 Radial spokehead-like protein PHO4 PF01384.15 KEG10256.1 - 2.6e-97 325.3 15.7 3.2e-97 325.1 10.9 1.1 1 0 0 1 1 1 1 Phosphate transporter family DcpS_C PF11969.3 KEG10257.1 - 1.6e-23 83.1 0.0 3.1e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 KEG10257.1 - 1.2e-14 54.5 0.1 3.4e-14 53.1 0.0 1.8 2 0 0 2 2 2 1 HIT domain SNARE PF05739.14 KEG10258.1 - 1.3e-06 28.0 0.2 1.8e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 SNARE domain ABC_tran PF00005.22 KEG10259.1 - 8.3e-53 178.3 0.0 6.4e-28 97.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 KEG10259.1 - 6.8e-51 173.3 44.7 2e-29 102.7 15.1 3.6 2 2 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 KEG10259.1 - 1.9e-12 47.7 0.2 0.015 15.2 0.0 4.2 4 0 0 4 4 4 3 AAA domain SMC_N PF02463.14 KEG10259.1 - 2.1e-07 30.4 0.0 0.037 13.2 0.1 3.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KEG10259.1 - 4.2e-05 22.9 2.6 0.0047 16.4 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.1 KEG10259.1 - 0.00033 20.4 0.0 1.2 9.0 0.0 3.5 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 KEG10259.1 - 0.00077 19.8 1.0 0.045 14.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 KEG10259.1 - 0.0099 15.3 1.2 0.71 9.2 0.2 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_15 PF13175.1 KEG10259.1 - 0.016 14.2 0.0 6 5.7 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain AAA_30 PF13604.1 KEG10259.1 - 0.02 14.5 0.4 0.81 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 KEG10259.1 - 0.075 11.4 0.7 0.26 9.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KEG10259.1 - 0.12 11.7 1.6 5.3 6.3 0.0 3.3 3 1 0 4 4 4 0 AAA domain DUF258 PF03193.11 KEG10259.1 - 0.17 11.0 0.3 5.1 6.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 KEG10259.1 - 0.29 11.0 2.0 2.9 7.7 0.0 2.7 3 0 0 3 3 2 0 AAA domain zf-CCHC_2 PF13696.1 KEG10260.1 - 3.2e-05 23.3 0.2 7.7e-05 22.1 0.1 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_jaz PF12171.3 KEG10260.1 - 0.00012 22.0 2.0 0.00029 20.8 1.4 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-CCHC_5 PF14787.1 KEG10260.1 - 0.0067 15.8 1.7 0.0067 15.8 1.2 2.6 4 0 0 4 4 4 1 GAG-polyprotein viral zinc-finger zf-C2H2_4 PF13894.1 KEG10260.1 - 0.02 15.2 0.6 0.02 15.2 0.4 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger ATP-synt_Eps PF04627.8 KEG10260.1 - 0.051 13.1 1.7 0.13 11.8 1.2 1.7 1 0 0 1 1 1 0 Mitochondrial ATP synthase epsilon chain NUFIP1 PF10453.4 KEG10260.1 - 0.12 11.8 0.0 0.12 11.8 0.0 2.7 2 0 0 2 2 2 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-C2H2 PF00096.21 KEG10260.1 - 0.19 12.1 8.7 3.9 7.9 2.6 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type Zip PF02535.17 KEG10261.1 - 5.2e-29 101.2 2.3 6.2e-29 101.0 1.6 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Nit_Regul_Hom PF10126.4 KEG10262.1 - 0.071 12.8 3.7 0.18 11.5 2.5 1.6 1 1 0 1 1 1 0 Uncharacterized protein, homolog of nitrogen regulatory protein PII S-AdoMet_synt_N PF00438.15 KEG10262.1 - 0.21 11.8 2.5 0.27 11.4 1.8 1.1 1 0 0 1 1 1 0 S-adenosylmethionine synthetase, N-terminal domain Peptidase_S15 PF02129.13 KEG10263.1 - 9.4e-61 205.6 1.8 1.8e-60 204.6 1.3 1.5 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 KEG10263.1 - 4e-34 118.4 0.0 5.7e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 KEG10263.1 - 3.6e-13 49.9 0.1 7.5e-13 48.8 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEG10263.1 - 4.4e-10 39.4 0.0 2.4e-09 37.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEG10263.1 - 5.1e-09 35.6 1.4 1.1e-07 31.3 0.5 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.7 KEG10263.1 - 4.7e-05 22.0 0.0 0.0018 16.8 0.0 2.2 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.3 KEG10263.1 - 0.00034 20.4 0.4 0.00087 19.0 0.3 1.8 1 1 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 KEG10263.1 - 0.00055 19.5 0.0 0.00081 19.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1100 PF06500.6 KEG10263.1 - 0.079 11.5 0.0 0.14 10.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) DLH PF01738.13 KEG10263.1 - 0.084 12.1 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family GTP_EFTU PF00009.22 KEG10264.1 - 1.2e-54 184.5 0.0 2e-54 183.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 KEG10264.1 - 6.1e-21 74.0 0.0 1.3e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 KEG10264.1 - 6.3e-15 54.8 0.1 1.3e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KEG10264.1 - 0.0001 22.3 0.0 0.00024 21.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KEG10264.1 - 0.00012 21.9 0.0 0.00026 20.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KEG10264.1 - 0.0025 18.2 0.0 0.0047 17.4 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 KEG10264.1 - 0.0087 15.1 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 AIG1 family FeoB_N PF02421.13 KEG10264.1 - 0.028 13.6 0.0 0.11 11.7 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B LacAB_rpiB PF02502.13 KEG10265.1 - 2.9e-48 163.0 0.1 3.3e-48 162.8 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Gly_rich_SFCGS PF14272.1 KEG10265.1 - 0.019 14.8 0.1 0.036 13.9 0.1 1.5 1 0 0 1 1 1 0 Glycine-rich SFCGS DUF4256 PF14066.1 KEG10265.1 - 0.07 12.6 0.0 0.084 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4256) DUF3689 PF12463.3 KEG10266.1 - 0.002 16.9 0.0 0.16 10.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3689) LRR_6 PF13516.1 KEG10267.1 - 1.8e-17 61.3 0.6 0.19 11.8 0.0 7.9 7 0 0 7 7 7 4 Leucine Rich repeat LRR_4 PF12799.2 KEG10267.1 - 4.6e-08 32.5 2.2 0.11 12.1 0.2 5.1 3 1 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEG10267.1 - 3e-07 29.5 0.2 3 8.2 0.0 6.7 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_8 PF13855.1 KEG10267.1 - 7.4e-07 28.8 0.4 0.033 13.9 0.0 3.9 3 1 1 4 4 4 3 Leucine rich repeat LRR_7 PF13504.1 KEG10267.1 - 0.01 15.8 5.4 4.3 7.9 0.0 5.9 7 0 0 7 7 7 0 Leucine rich repeat CAP_N PF01213.14 KEG10267.1 - 0.021 14.1 0.8 0.04 13.1 0.6 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DivIC PF04977.10 KEG10267.1 - 0.19 11.2 1.8 0.55 9.7 1.3 1.8 1 0 0 1 1 1 0 Septum formation initiator SMN PF06003.7 KEG10267.1 - 7.3 5.6 12.8 1.3 8.0 5.0 2.5 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) Lin-8 PF03353.10 KEG10267.1 - 8.6 5.5 7.8 16 4.6 5.4 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist EF-hand_1 PF00036.27 KEG10270.1 - 9.2e-13 46.5 6.5 9.7e-07 27.6 0.0 5.4 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.1 KEG10270.1 - 2.4e-10 39.3 4.1 3.3e-05 23.3 0.0 4.8 5 0 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.1 KEG10270.1 - 4.2e-09 35.3 4.6 0.00024 20.2 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 KEG10270.1 - 2.7e-08 33.8 2.5 0.00012 22.1 0.0 4.3 5 1 0 5 5 5 2 EF-hand domain pair EF-hand_8 PF13833.1 KEG10270.1 - 2.9e-08 33.2 3.1 0.018 14.6 0.0 5.5 6 0 0 6 6 6 3 EF-hand domain pair RmlD_sub_bind PF04321.12 KEG10271.1 - 9.9e-06 24.6 0.0 0.066 12.0 0.0 2.3 2 0 0 2 2 2 2 RmlD substrate binding domain NAD_binding_10 PF13460.1 KEG10271.1 - 0.00013 21.9 0.0 0.00023 21.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KEG10271.1 - 0.041 13.1 0.0 0.055 12.7 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Ribosomal_S6e PF01092.14 KEG10272.1 - 3.6e-41 139.7 1.7 4.1e-41 139.5 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein S6e HTH_20 PF12840.2 KEG10273.1 - 0.038 13.7 0.7 0.038 13.7 0.5 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Guanylate_kin PF00625.16 KEG10274.1 - 1.4e-52 177.8 0.0 1.7e-52 177.5 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.1 KEG10274.1 - 3.7e-07 30.1 0.0 5.8e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KEG10274.1 - 4.6e-07 30.2 0.1 1.1e-06 29.0 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEG10274.1 - 4.9e-05 24.1 0.1 0.00016 22.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 KEG10274.1 - 0.00033 20.6 0.0 0.00053 19.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KEG10274.1 - 0.0018 18.4 0.1 0.0087 16.1 0.0 2.1 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 KEG10274.1 - 0.0022 17.2 0.1 0.0085 15.2 0.0 2.0 2 1 0 2 2 2 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 KEG10274.1 - 0.0038 17.5 0.2 0.18 12.0 0.1 2.3 1 1 0 1 1 1 1 ABC transporter 2_5_RNA_ligase2 PF13563.1 KEG10274.1 - 0.018 14.7 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily ADK PF00406.17 KEG10274.1 - 0.021 14.6 0.4 0.97 9.3 0.1 2.2 2 0 0 2 2 2 0 Adenylate kinase AAA_16 PF13191.1 KEG10274.1 - 0.057 13.3 0.0 0.12 12.3 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.9 KEG10274.1 - 0.065 12.9 0.1 0.39 10.4 0.0 2.1 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) Miro PF08477.8 KEG10274.1 - 0.1 13.0 0.0 0.15 12.5 0.0 1.5 1 1 0 1 1 1 0 Miro-like protein YEATS PF03366.11 KEG10275.1 - 5.5e-11 42.0 0.0 9.8e-11 41.2 0.0 1.3 1 0 0 1 1 1 1 YEATS family Cut8_N PF14482.1 KEG10275.1 - 0.25 11.3 7.6 1 9.4 0.7 2.6 2 0 0 2 2 2 0 Cut8 proteasome-binding domain Voltage_CLC PF00654.15 KEG10276.1 - 1.4e-87 294.0 27.3 4.5e-87 292.3 17.1 2.5 2 1 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 KEG10276.1 - 1.7e-10 40.5 1.2 1.1e-05 25.1 0.1 2.5 2 0 0 2 2 2 2 CBS domain Abhydrolase_5 PF12695.2 KEG10277.1 - 0.0017 18.1 0.0 0.0049 16.6 0.0 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEG10277.1 - 0.0021 17.9 0.0 0.036 13.9 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KEG10277.1 - 0.0054 16.1 0.0 0.057 12.8 0.0 2.0 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 KEG10277.1 - 0.014 14.5 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KEG10277.1 - 0.035 13.6 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Fez1 PF06818.10 KEG10278.1 - 0.24 11.3 9.9 0.12 12.3 4.9 1.9 2 0 0 2 2 2 0 Fez1 PPTA PF01239.17 KEG10281.1 - 1.1e-24 84.6 8.5 1.4e-06 27.4 0.4 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Peptidase_M3 PF01432.15 KEG10282.1 - 5.2e-112 375.1 0.0 7.6e-112 374.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 KEG10282.1 - 0.032 13.5 0.6 0.072 12.4 0.1 1.7 2 0 0 2 2 2 0 Peptidase M50B-like PQQ_3 PF13570.1 KEG10283.1 - 0.008 16.4 0.0 0.072 13.3 0.0 2.6 3 0 0 3 3 3 1 PQQ-like domain WD40 PF00400.27 KEG10283.1 - 0.016 15.1 2.3 0.11 12.3 0.2 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat WD40 PF00400.27 KEG10284.1 - 2.7e-23 80.9 1.3 2.8e-09 36.5 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat EF-hand_7 PF13499.1 KEG10284.1 - 2e-11 43.8 0.3 4.9e-11 42.5 0.2 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 KEG10284.1 - 2.9e-08 33.2 0.3 4.7e-07 29.3 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KEG10284.1 - 1.5e-07 30.7 0.2 0.00055 19.5 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 KEG10284.1 - 5.8e-07 28.3 0.1 7.1e-05 21.8 0.1 2.7 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 KEG10284.1 - 6.1e-05 22.1 0.2 0.0002 20.5 0.1 1.9 1 0 0 1 1 1 1 EF hand Cytochrom_D1 PF02239.11 KEG10284.1 - 0.00018 19.9 0.1 0.00032 19.1 0.1 1.5 1 1 0 1 1 1 1 Cytochrome D1 heme domain SPARC_Ca_bdg PF10591.4 KEG10284.1 - 0.0047 16.9 0.0 0.0092 16.0 0.0 1.5 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 KEG10284.1 - 0.053 13.1 0.1 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 EF hand Pro_dh PF01619.13 KEG10285.1 - 1.2e-54 185.3 0.0 1.8e-54 184.8 0.0 1.2 1 0 0 1 1 1 1 Proline dehydrogenase EF-hand_8 PF13833.1 KEG10285.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair CTP_transf_1 PF01148.15 KEG10286.1 - 1e-61 208.8 23.0 1.5e-61 208.3 16.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family Ribosomal_S28e PF01200.13 KEG10287.1 - 2.1e-30 104.2 3.3 2.6e-30 103.9 2.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S28e DUF2135 PF09906.4 KEG10287.1 - 0.017 15.0 0.1 0.029 14.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2135) MIT PF04212.13 KEG10288.1 - 0.089 12.6 6.2 0.23 11.3 0.2 2.8 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain LRR_6 PF13516.1 KEG10289.1 - 1.1e-08 34.2 9.9 0.0014 18.4 0.1 8.3 11 0 0 11 11 11 1 Leucine Rich repeat LRR_4 PF12799.2 KEG10289.1 - 6.6e-08 32.0 0.4 0.099 12.2 0.0 5.8 4 2 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEG10289.1 - 2.2e-05 23.8 8.1 12 6.3 0.0 8.7 10 1 0 10 10 10 1 Leucine Rich Repeat LRR_8 PF13855.1 KEG10289.1 - 0.01 15.5 4.1 1.4 8.7 0.0 4.8 4 1 0 4 4 4 0 Leucine rich repeat LRR_7 PF13504.1 KEG10289.1 - 0.027 14.6 18.9 72 4.2 0.0 9.5 9 1 1 10 10 10 0 Leucine rich repeat PCI PF01399.22 KEG10290.1 - 7e-12 45.6 0.0 3.6e-11 43.3 0.0 2.2 2 1 0 2 2 2 1 PCI domain HyaE PF07449.6 KEG10290.1 - 0.014 15.2 0.1 0.056 13.3 0.1 2.0 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE UFD1 PF03152.9 KEG10292.1 - 7.6e-49 165.2 0.0 9.3e-49 164.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Pkinase PF00069.20 KEG10293.1 - 5.4e-68 228.9 0.0 6.3e-68 228.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG10293.1 - 6e-33 114.0 0.0 7.3e-33 113.7 0.0 1.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG10293.1 - 7.1e-13 48.1 0.0 2.4e-12 46.4 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 KEG10293.1 - 5.1e-07 28.9 0.4 1.3e-06 27.6 0.2 1.7 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEG10293.1 - 0.0038 16.9 0.5 0.18 11.4 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family MAT1 PF06391.8 KEG10294.1 - 0.15 11.5 25.5 0.16 11.5 6.1 2.6 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 MIP-T3 PF10243.4 KEG10294.1 - 0.38 9.1 39.4 0.13 10.7 15.1 2.2 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 DUF4355 PF14265.1 KEG10294.1 - 3.7 7.5 38.5 0.099 12.5 8.9 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4355) BPD_transp_2 PF02653.11 KEG10295.1 - 0.27 10.1 10.9 0.35 9.7 7.5 1.1 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component DUF2976 PF11190.3 KEG10295.1 - 0.36 10.3 5.9 8.1 6.0 2.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Tmemb_161AB PF10268.4 KEG10295.1 - 1.9 6.9 8.2 0.31 9.5 1.0 2.0 1 1 1 2 2 2 0 Predicted transmembrane protein 161AB FdhD-NarQ PF02634.10 KEG10296.1 - 0.11 11.9 0.2 0.14 11.6 0.1 1.2 1 0 0 1 1 1 0 FdhD/NarQ family Sec23_trunk PF04811.10 KEG10298.1 - 2.8e-50 170.9 0.0 4.2e-50 170.3 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KEG10298.1 - 2.5e-28 97.5 0.2 4.3e-28 96.7 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KEG10298.1 - 3.8e-19 68.9 0.5 1e-18 67.6 0.3 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KEG10298.1 - 1e-13 50.5 4.4 2.1e-13 49.5 3.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KEG10298.1 - 1.8e-05 24.3 0.0 6.4e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 Gelsolin repeat TB2_DP1_HVA22 PF03134.14 KEG10299.1 - 2.7e-05 23.8 0.8 4.9e-05 22.9 0.6 1.5 1 0 0 1 1 1 1 TB2/DP1, HVA22 family APG6 PF04111.7 KEG10301.1 - 4e-14 52.3 0.0 5.7e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 PBP_GOBP PF01395.17 KEG10301.1 - 0.061 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 PBP/GOBP family WD40 PF00400.27 KEG10302.1 - 1.6e-39 132.3 26.1 2.4e-08 33.5 0.3 10.3 10 1 0 10 10 10 7 WD domain, G-beta repeat BBS2_Mid PF14783.1 KEG10302.1 - 4.9e-06 26.2 4.1 0.0047 16.6 0.1 4.7 4 1 1 6 6 6 2 Ciliary BBSome complex subunit 2, middle region Apc4_WD40 PF12894.2 KEG10302.1 - 0.00092 18.6 0.0 4 7.0 0.0 4.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Stimulus_sens_1 PF13756.1 KEG10303.1 - 0.04 14.3 0.3 0.04 14.3 0.2 2.8 2 0 0 2 2 2 0 Stimulus-sensing domain PWWP PF00855.12 KEG10304.1 - 0.082 13.1 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 PWWP domain Zip PF02535.17 KEG10305.1 - 0.00036 19.6 8.9 0.00047 19.2 6.1 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter DUF4175 PF13779.1 KEG10305.1 - 1.5 6.4 10.8 2.3 5.8 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Mito_carr PF00153.22 KEG10308.1 - 1.6e-53 178.3 4.3 1.4e-20 72.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein NHL PF01436.16 KEG10309.1 - 0.00021 21.0 4.6 0.025 14.5 0.1 3.7 4 0 0 4 4 4 2 NHL repeat DUF4392 PF14336.1 KEG10309.1 - 0.016 13.9 0.0 0.025 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) Rax2 PF12768.2 KEG10310.1 - 0.061 12.5 0.0 0.17 11.0 0.0 1.6 2 0 0 2 2 2 0 Cortical protein marker for cell polarity SecA_DEAD PF07517.9 KEG10311.1 - 1e-37 129.8 0.0 2.2e-37 128.8 0.0 1.5 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_PP_bind PF01043.15 KEG10311.1 - 4.3e-06 27.0 0.5 1.7e-05 25.1 0.1 2.3 2 0 0 2 2 2 1 SecA preprotein cross-linking domain TPR_11 PF13414.1 KEG10311.1 - 3e-05 23.5 5.7 0.00011 21.7 3.9 2.1 1 0 0 1 1 1 1 TPR repeat DEAD PF00270.24 KEG10311.1 - 0.00025 20.6 0.0 0.00062 19.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase TPR_2 PF07719.12 KEG10311.1 - 0.017 14.9 0.4 0.017 14.9 0.3 3.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 KEG10311.1 - 0.51 11.0 9.0 0.15 12.8 2.8 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Spc24 PF08286.6 KEG10312.1 - 0.12 12.0 5.0 0.2 11.3 3.2 1.5 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 IncA PF04156.9 KEG10312.1 - 0.23 11.0 7.2 0.29 10.7 5.0 1.2 1 0 0 1 1 1 0 IncA protein Troponin PF00992.15 KEG10312.1 - 0.34 10.9 11.7 0.64 10.0 8.1 1.4 1 0 0 1 1 1 0 Troponin APG6 PF04111.7 KEG10312.1 - 2.4 7.1 9.9 3.6 6.5 6.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 KEG10312.1 - 4.8 6.0 7.5 6.3 5.6 5.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 AAA_27 PF13514.1 KEG10313.1 - 0.00078 17.2 5.9 0.00081 17.2 4.1 1.0 1 0 0 1 1 1 1 AAA domain ADIP PF11559.3 KEG10313.1 - 0.0018 18.2 9.4 0.002 18.0 6.5 1.0 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding TraC PF07820.7 KEG10313.1 - 0.0037 17.4 1.8 0.0059 16.7 1.3 1.3 1 0 0 1 1 1 1 TraC-like protein HrpB7 PF09486.5 KEG10313.1 - 0.0095 15.8 3.3 0.011 15.7 2.3 1.1 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) DUF3847 PF12958.2 KEG10313.1 - 0.011 15.4 6.5 0.014 15.1 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) BLOC1_2 PF10046.4 KEG10313.1 - 0.013 15.6 2.1 0.015 15.3 1.4 1.0 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Atg14 PF10186.4 KEG10313.1 - 0.019 13.9 8.6 0.02 13.8 5.9 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Spc7 PF08317.6 KEG10313.1 - 0.021 13.5 7.6 0.023 13.3 5.3 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Filament PF00038.16 KEG10313.1 - 0.021 14.3 8.2 0.023 14.1 5.7 1.0 1 0 0 1 1 1 0 Intermediate filament protein DUF812 PF05667.6 KEG10313.1 - 0.023 13.2 6.2 0.026 13.0 4.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) APG6 PF04111.7 KEG10313.1 - 0.023 13.7 8.4 0.024 13.7 5.8 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Myosin_tail_1 PF01576.14 KEG10313.1 - 0.027 12.2 8.8 0.031 12.0 6.1 1.0 1 0 0 1 1 1 0 Myosin tail TPR_MLP1_2 PF07926.7 KEG10313.1 - 0.031 14.0 9.8 0.042 13.5 6.8 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DASH_Spc34 PF08657.5 KEG10313.1 - 0.033 13.8 3.5 0.034 13.8 2.4 1.2 1 0 0 1 1 1 0 DASH complex subunit Spc34 FliD_N PF02465.13 KEG10313.1 - 0.034 14.5 2.3 0.048 14.0 1.6 1.2 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Lipoprotein_20 PF13942.1 KEG10313.1 - 0.039 13.4 5.5 0.043 13.3 3.8 1.1 1 0 0 1 1 1 0 YfhG lipoprotein MT PF12777.2 KEG10313.1 - 0.049 12.3 0.8 0.057 12.1 0.6 1.1 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor Macoilin PF09726.4 KEG10313.1 - 0.064 11.5 5.2 0.073 11.3 3.6 1.0 1 0 0 1 1 1 0 Transmembrane protein CENP-F_leu_zip PF10473.4 KEG10313.1 - 0.075 12.8 10.4 0.092 12.5 7.2 1.0 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF948 PF06103.6 KEG10313.1 - 0.11 12.4 0.8 0.13 12.1 0.6 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) WEMBL PF05701.6 KEG10313.1 - 0.11 10.9 10.0 0.11 10.9 7.0 1.0 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Tropomyosin_1 PF12718.2 KEG10313.1 - 0.12 12.2 12.1 0.15 11.9 8.4 1.0 1 0 0 1 1 1 0 Tropomyosin like Lge1 PF11488.3 KEG10313.1 - 0.19 11.9 5.4 0.22 11.7 3.7 1.1 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 DUF4200 PF13863.1 KEG10313.1 - 0.19 11.6 11.5 0.27 11.1 8.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Pox_H7 PF04787.7 KEG10313.1 - 0.2 11.4 0.6 0.23 11.2 0.4 1.1 1 0 0 1 1 1 0 Late protein H7 TMF_DNA_bd PF12329.3 KEG10313.1 - 0.21 11.4 11.5 1.5 8.6 2.0 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding ATG16 PF08614.6 KEG10313.1 - 0.21 11.3 8.9 0.26 11.0 6.2 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) IncA PF04156.9 KEG10313.1 - 0.22 11.1 9.2 0.24 10.9 6.4 1.0 1 0 0 1 1 1 0 IncA protein TBPIP PF07106.8 KEG10313.1 - 0.22 11.0 7.4 0.24 10.9 5.2 1.0 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TMCO5 PF14992.1 KEG10313.1 - 0.24 10.4 4.9 0.25 10.4 3.4 1.0 1 0 0 1 1 1 0 TMCO5 family DivIC PF04977.10 KEG10313.1 - 0.24 10.8 13.0 0.15 11.5 7.3 1.7 1 1 1 2 2 2 0 Septum formation initiator Mod_r PF07200.8 KEG10313.1 - 0.26 11.1 7.7 0.3 10.9 5.3 1.0 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF4094 PF13334.1 KEG10313.1 - 0.31 11.4 3.3 0.34 11.3 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) CCDC155 PF14662.1 KEG10313.1 - 0.33 10.5 10.3 0.38 10.3 7.2 1.0 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 Cluap1 PF10234.4 KEG10313.1 - 0.34 10.0 7.3 0.4 9.8 5.0 1.0 1 0 0 1 1 1 0 Clusterin-associated protein-1 AAA_13 PF13166.1 KEG10313.1 - 0.36 9.2 6.3 0.4 9.0 4.4 1.0 1 0 0 1 1 1 0 AAA domain DUF607 PF04678.8 KEG10313.1 - 0.41 10.5 2.4 0.45 10.4 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF607 IFT20 PF14931.1 KEG10313.1 - 0.42 10.5 10.2 0.49 10.2 7.1 1.2 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 Nup54 PF13874.1 KEG10313.1 - 0.42 10.2 6.7 0.35 10.5 4.2 1.2 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 FimP PF09766.4 KEG10313.1 - 0.46 9.5 7.3 0.48 9.4 5.0 1.0 1 0 0 1 1 1 0 Fms-interacting protein DUF641 PF04859.7 KEG10313.1 - 0.49 10.1 4.7 0.56 9.9 3.3 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Viral_P18 PF04521.8 KEG10313.1 - 0.49 9.8 3.6 0.63 9.4 2.4 1.3 1 1 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein V-SNARE PF05008.10 KEG10313.1 - 0.5 10.5 8.0 1.2 9.3 5.2 1.8 1 1 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus DUF2968 PF11180.3 KEG10313.1 - 0.55 9.5 9.4 0.52 9.6 5.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) Phage_Mu_Gam PF07352.7 KEG10313.1 - 0.62 9.5 6.5 0.45 10.0 3.6 1.4 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein DUF4407 PF14362.1 KEG10313.1 - 0.75 8.6 5.3 0.9 8.4 3.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc24 PF08286.6 KEG10313.1 - 0.76 9.4 8.4 0.91 9.2 5.8 1.1 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF342 PF03961.8 KEG10313.1 - 0.76 8.1 4.8 0.82 8.0 3.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) PEP-utilisers_N PF05524.8 KEG10313.1 - 0.77 9.5 5.9 0.85 9.4 4.1 1.1 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Mnd1 PF03962.10 KEG10313.1 - 0.85 9.2 8.5 1.9 8.0 5.9 1.6 1 1 0 1 1 1 0 Mnd1 family DUF3450 PF11932.3 KEG10313.1 - 0.89 8.7 7.1 1.1 8.5 4.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Prefoldin_2 PF01920.15 KEG10313.1 - 0.9 9.3 10.2 1.4 8.6 6.7 1.6 1 1 0 1 1 1 0 Prefoldin subunit Prefoldin PF02996.12 KEG10313.1 - 1.2 8.7 8.2 1 8.9 3.1 1.9 1 1 1 2 2 2 0 Prefoldin subunit CENP-H PF05837.7 KEG10313.1 - 1.3 9.2 7.4 1.5 9.0 5.1 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF3340 PF11818.3 KEG10313.1 - 1.5 8.7 6.4 1.6 8.6 4.5 1.1 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) DUF4337 PF14235.1 KEG10313.1 - 1.5 8.6 6.9 1.7 8.4 4.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) FemAB PF02388.11 KEG10313.1 - 1.5 7.4 6.2 1.5 7.4 4.3 1.0 1 0 0 1 1 1 0 FemAB family V_ATPase_I PF01496.14 KEG10313.1 - 2.2 6.0 4.7 2.2 6.0 3.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF837 PF05769.6 KEG10313.1 - 2.3 7.7 9.6 1.4 8.3 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF837) FKBP_N PF01346.13 KEG10313.1 - 2.5 8.1 7.0 3 7.8 4.9 1.2 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF2346 PF09803.4 KEG10313.1 - 2.6 7.9 4.6 3 7.7 3.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2346) 4HB_MCP_1 PF12729.2 KEG10313.1 - 2.9 7.2 6.5 8.5 5.6 2.9 1.9 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction DUF4140 PF13600.1 KEG10313.1 - 3.1 8.3 8.5 4.6 7.7 5.9 1.4 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Clusterin PF01093.12 KEG10313.1 - 3.9 6.1 8.7 4.2 6.0 6.1 1.0 1 0 0 1 1 1 0 Clusterin Borrelia_P83 PF05262.6 KEG10313.1 - 4 5.5 9.1 4.3 5.5 6.3 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Ras PF00071.17 KEG10315.1 - 3.5e-47 159.7 0.0 4.2e-47 159.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEG10315.1 - 3.7e-13 50.0 0.0 6.2e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEG10315.1 - 4.5e-08 32.5 0.0 5.3e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KEG10315.1 - 0.00012 21.3 0.0 0.00013 21.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KEG10315.1 - 0.001 18.5 0.0 0.017 14.5 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain YTH PF04146.10 KEG10315.1 - 0.053 13.1 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 YT521-B-like domain MMR_HSR1 PF01926.18 KEG10315.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase RIB43A PF05914.7 KEG10317.1 - 3.7e-103 345.1 60.4 4.4e-103 344.8 41.9 1.0 1 0 0 1 1 1 1 RIB43A zf-RanBP PF00641.13 KEG10318.1 - 6.7e-11 41.0 23.6 3.1e-05 22.9 3.1 3.4 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others DZR PF12773.2 KEG10318.1 - 1.6e-06 27.8 18.8 0.0022 17.7 5.7 2.4 1 1 1 2 2 2 2 Double zinc ribbon DUF3279 PF11682.3 KEG10318.1 - 0.061 12.8 10.8 1.2 8.7 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3279) zf-RING_3 PF14369.1 KEG10318.1 - 0.14 12.1 0.6 0.14 12.1 0.4 3.0 4 0 0 4 4 4 0 zinc-finger zf-ribbon_3 PF13248.1 KEG10318.1 - 0.36 10.0 22.8 0.07 12.3 1.8 3.4 3 0 0 3 3 3 0 zinc-ribbon domain Peptidase_S46 PF10459.4 KEG10320.1 - 0.68 8.2 38.1 1.4 7.2 1.2 3.1 2 1 0 3 3 3 0 Peptidase S46 Atx10homo_assoc PF09759.4 KEG10321.1 - 6.4e-30 102.8 0.0 1.6e-29 101.6 0.0 1.7 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain WAPL PF07814.8 KEG10321.1 - 0.0078 14.9 0.5 0.02 13.6 0.1 1.7 1 1 1 2 2 2 1 Wings apart-like protein regulation of heterochromatin LRR_6 PF13516.1 KEG10326.1 - 4.9e-28 94.0 11.1 0.0028 17.5 0.0 9.4 9 1 0 9 9 9 7 Leucine Rich repeat LRR_4 PF12799.2 KEG10326.1 - 2.8e-18 65.0 12.7 2.3e-06 27.0 0.1 6.7 4 2 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG10326.1 - 7.9e-10 38.3 20.0 0.00069 19.3 1.2 6.4 1 1 8 9 9 9 7 Leucine rich repeat LRR_1 PF00560.28 KEG10326.1 - 1.7e-07 30.3 21.7 0.67 10.2 0.2 9.3 8 3 1 9 9 9 2 Leucine Rich Repeat LRR_7 PF13504.1 KEG10326.1 - 0.00043 20.0 22.4 6.2 7.4 0.0 8.9 8 2 0 8 8 8 2 Leucine rich repeat Yip1 PF04893.12 KEG10327.1 - 8.3e-08 31.9 17.4 1.1e-07 31.4 11.4 1.6 1 1 1 2 2 2 1 Yip1 domain GATase PF00117.23 KEG10328.1 - 8.3e-10 38.4 0.1 1.2e-09 37.9 0.1 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KEG10328.1 - 4.5e-07 29.5 0.9 2.7e-06 27.0 0.1 2.4 2 1 0 2 2 2 1 Peptidase C26 tRNA-synt_2 PF00152.15 KEG10329.1 - 6e-89 298.1 0.0 7.6e-89 297.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KEG10329.1 - 9e-11 41.4 0.2 2e-10 40.3 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KEG10329.1 - 1.2e-08 34.4 0.1 0.00019 20.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 KEG10329.1 - 0.0053 16.3 0.1 2.7 7.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) FAD-oxidase_C PF02913.14 KEG10330.1 - 5.7e-54 183.0 0.0 9.6e-54 182.3 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KEG10330.1 - 1.7e-36 124.7 0.2 2.9e-36 123.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain LRR_4 PF12799.2 KEG10331.1 - 2.1e-09 36.7 0.0 0.011 15.3 0.0 4.1 2 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG10331.1 - 4.6e-07 29.5 0.2 0.016 14.9 0.0 3.8 4 0 0 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 KEG10331.1 - 0.012 15.4 1.5 57 4.3 0.0 5.3 5 1 1 6 6 6 0 Leucine Rich Repeat LRR_7 PF13504.1 KEG10331.1 - 0.051 13.7 2.6 71 4.3 0.0 4.9 5 0 0 5 5 5 0 Leucine rich repeat NACHT PF05729.7 KEG10332.1 - 8e-05 22.3 0.0 0.00015 21.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain WD40 PF00400.27 KEG10332.1 - 0.0001 21.9 14.1 0.00047 19.9 0.4 4.8 5 1 0 5 5 5 2 WD domain, G-beta repeat DUF2415 PF10313.4 KEG10332.1 - 0.0036 16.9 0.4 0.041 13.5 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) Beach PF02138.13 KEG10334.1 - 1e-87 294.0 0.0 2.4e-87 292.8 0.0 1.7 2 0 0 2 2 2 1 Beige/BEACH domain Pox_RNA_Pol_19 PF05320.7 KEG10334.1 - 0.018 14.8 0.6 0.037 13.7 0.4 1.4 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit eIF3_subunit PF08597.5 KEG10334.1 - 2.5 7.6 4.3 4.2 6.8 3.0 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Spt5_N PF11942.3 KEG10334.1 - 3.6 8.2 9.6 11 6.6 6.7 1.9 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal UQ_con PF00179.21 KEG10336.1 - 8.8e-34 115.9 0.0 1.4e-33 115.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KEG10336.1 - 0.081 12.6 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B Aminotran_5 PF00266.14 KEG10338.1 - 6.2e-26 91.0 0.0 8.3e-26 90.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Methyltransf_24 PF13578.1 KEG10338.1 - 0.048 14.5 0.0 19 6.1 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Pkinase PF00069.20 KEG10339.1 - 5.8e-55 186.2 0.0 1.4e-38 132.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEG10339.1 - 1.5e-33 116.0 0.0 3.1e-33 114.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG10339.1 - 3.5e-10 39.3 0.0 6.1e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KEG10339.1 - 0.041 12.7 0.0 0.066 12.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pribosyltran PF00156.22 KEG10340.1 - 1.2e-15 57.3 0.1 1.4e-13 50.6 0.0 2.1 2 0 0 2 2 2 2 Phosphoribosyl transferase domain Pribosyltran PF00156.22 KEG10341.1 - 1.9e-14 53.4 0.0 3.1e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain YABBY PF04690.8 KEG10341.1 - 0.1 12.8 0.1 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 YABBY protein DUF2730 PF10805.3 KEG10342.1 - 0.0037 16.9 0.1 0.013 15.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2730) Peptidase_M24 PF00557.19 KEG10343.1 - 1.7e-42 145.3 0.1 2.4e-42 144.8 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF3499 PF12005.3 KEG10343.1 - 2.9 8.0 7.0 0.53 10.4 1.6 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3499) DUF2009 PF09418.5 KEG10344.1 - 0.15 10.8 0.0 0.2 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) Gypsy PF07253.6 KEG10345.1 - 0.065 11.5 0.1 0.081 11.2 0.0 1.1 1 0 0 1 1 1 0 Gypsy protein GSH_synth_ATP PF03917.12 KEG10346.1 - 2.6e-56 190.7 0.0 3.2e-56 190.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 KEG10346.1 - 5.2e-37 126.1 0.0 4.4e-36 123.1 0.0 2.4 2 0 0 2 2 2 1 Eukaryotic glutathione synthase PXA PF02194.10 KEG10346.1 - 0.093 12.2 1.8 0.31 10.5 1.3 1.9 1 1 0 1 1 1 0 PXA domain Pam16 PF03656.8 KEG10346.1 - 0.11 12.2 0.4 0.9 9.3 0.0 2.3 2 0 0 2 2 2 0 Pam16 DNA_pol_A PF00476.15 KEG10347.1 - 2.2e-27 95.6 0.0 5.7e-27 94.3 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family A DUF2675 PF11247.3 KEG10348.1 - 0.012 15.7 0.1 3.4 7.8 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2675) CDK5_activator PF03261.10 KEG10348.1 - 1.9 7.7 10.2 0.072 12.4 2.1 2.0 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein Mannitol_dh_C PF08125.8 KEG10349.1 - 7.3e-55 185.8 0.0 1.1e-54 185.2 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 KEG10349.1 - 1.4e-33 115.9 0.0 2.2e-33 115.3 0.0 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain Cnd2 PF05786.9 KEG10350.1 - 4.1e-11 42.1 0.5 7.8e-11 41.2 0.4 1.4 1 0 0 1 1 1 1 Condensin complex subunit 2 NAD_kinase PF01513.16 KEG10351.1 - 1.6e-16 59.9 0.0 2.5e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 KEG10351.1 - 0.068 12.6 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain CLN3 PF02487.12 KEG10352.1 - 1.1e-11 44.1 14.0 9.5e-10 37.8 5.3 2.0 1 1 1 2 2 2 2 CLN3 protein TPR_12 PF13424.1 KEG10354.1 - 2.5e-09 36.9 1.5 7.1e-09 35.4 0.3 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 KEG10354.1 - 2.8e-05 23.6 1.0 8.6e-05 22.1 0.2 2.1 2 0 0 2 2 2 1 TPR repeat TPR_10 PF13374.1 KEG10354.1 - 0.00032 20.5 6.6 0.00049 19.9 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEG10354.1 - 0.00046 19.6 2.4 0.061 12.9 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEG10354.1 - 0.0029 17.3 0.7 0.065 13.1 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEG10354.1 - 0.031 14.0 0.3 0.23 11.3 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat SERTA PF06031.8 KEG10354.1 - 0.091 12.0 0.1 0.29 10.4 0.1 1.9 1 0 0 1 1 1 0 SERTA motif Mnd1 PF03962.10 KEG10355.1 - 0.045 13.4 22.2 0.62 9.6 7.6 3.0 1 1 2 3 3 3 0 Mnd1 family Effector_1 PF04518.7 KEG10355.1 - 0.054 12.4 6.9 0.048 12.6 3.8 1.6 1 1 0 1 1 1 0 Effector from type III secretion system Tweety PF04906.8 KEG10355.1 - 0.23 9.8 2.2 0.3 9.4 1.1 1.4 1 1 0 1 1 1 0 Tweety NPV_P10 PF05531.7 KEG10355.1 - 0.5 10.6 4.4 19 5.5 0.1 3.6 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein TMPIT PF07851.8 KEG10355.1 - 0.55 9.2 9.4 0.18 10.8 1.3 2.1 2 0 0 2 2 2 0 TMPIT-like protein Spc7 PF08317.6 KEG10355.1 - 3.5 6.1 17.0 0.18 10.4 7.0 1.9 1 1 0 2 2 2 0 Spc7 kinetochore protein Kinesin PF00225.18 KEG10356.1 - 8.7e-06 24.6 0.0 1.1e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain DUF2392 PF10288.4 KEG10359.1 - 1.9e-09 37.8 0.0 3.8e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) ATP_bind_3 PF01171.15 KEG10359.1 - 0.0084 15.6 0.0 0.07 12.6 0.0 2.2 2 0 0 2 2 2 1 PP-loop family Pkinase PF00069.20 KEG10360.1 - 1.2e-39 136.0 0.1 1.3e-33 116.2 0.0 3.3 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEG10360.1 - 2.1e-17 63.0 0.0 6.8e-17 61.4 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG10360.1 - 0.011 14.6 0.0 0.035 13.0 0.0 1.8 2 0 0 2 2 2 0 Kinase-like CtIP_N PF10482.4 KEG10360.1 - 0.046 13.5 0.5 0.11 12.3 0.4 1.6 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain HBS1_N PF08938.5 KEG10360.1 - 0.087 12.9 0.4 8 6.6 0.1 2.7 2 0 0 2 2 2 0 HBS1 N-terminus TRI5 PF06330.6 KEG10360.1 - 0.089 11.4 0.2 3 6.3 0.0 2.1 2 0 0 2 2 2 0 Trichodiene synthase (TRI5) DSPc PF00782.15 KEG10361.1 - 2.2e-07 30.5 0.6 8e-07 28.7 0.1 2.1 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KEG10361.1 - 0.0043 16.4 0.1 0.58 9.4 0.0 2.2 1 1 1 2 2 2 2 Protein-tyrosine phosphatase C2 PF00168.25 KEG10362.1 - 1.7e-16 59.8 0.1 3.6e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 C2 domain SpecificRecomb PF10136.4 KEG10362.1 - 0.035 12.1 0.0 0.057 11.4 0.0 1.2 1 0 0 1 1 1 0 Site-specific recombinase ubiquitin PF00240.18 KEG10365.1 - 2.4e-06 26.8 0.0 5e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 KEG10365.1 - 0.0055 16.8 0.6 0.017 15.3 0.4 1.8 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 KEG10365.1 - 0.051 13.4 0.1 0.47 10.3 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like PseudoU_synth_2 PF00849.17 KEG10366.1 - 2.3e-20 73.0 0.0 3.6e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase TPR_11 PF13414.1 KEG10367.1 - 6e-13 48.2 2.1 3e-08 33.1 0.3 2.5 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KEG10367.1 - 5.2e-10 38.4 4.5 0.011 15.2 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEG10367.1 - 4.5e-09 35.5 4.9 0.028 14.3 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KEG10367.1 - 1.2e-08 35.3 0.9 1.3e-06 28.8 0.2 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KEG10367.1 - 8.7e-07 28.7 3.1 6.1e-06 26.0 0.2 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 KEG10367.1 - 5.5e-05 23.0 0.5 0.84 9.9 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 KEG10367.1 - 0.00036 20.7 0.1 0.086 13.3 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEG10367.1 - 0.00038 20.0 0.5 0.63 9.9 0.0 3.2 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 KEG10367.1 - 0.00066 19.4 0.1 0.0022 17.7 0.1 1.9 1 1 1 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 KEG10367.1 - 0.0011 19.0 2.2 0.0051 16.9 0.1 2.6 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 KEG10367.1 - 0.0012 19.2 1.3 1.3 9.8 0.1 3.2 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 KEG10367.1 - 0.0035 17.2 5.1 0.019 14.9 0.1 3.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEG10367.1 - 0.0068 16.1 1.1 5.8 6.9 0.1 3.2 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_4 PF07721.9 KEG10367.1 - 0.017 15.4 2.1 4.2 8.0 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3166 PF11365.3 KEG10367.1 - 0.038 14.4 0.1 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF3166) TPR_19 PF14559.1 KEG10367.1 - 0.097 13.0 6.3 3.5 8.0 0.1 3.2 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.4 KEG10367.1 - 5.6 6.8 7.4 17 5.3 0.1 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat MRP-L47 PF06984.8 KEG10368.1 - 7.8e-26 89.8 0.1 1.6e-25 88.8 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) FRQ PF09421.5 KEG10368.1 - 0.0043 14.9 1.6 0.0055 14.5 1.1 1.1 1 0 0 1 1 1 1 Frequency clock protein GRIM-19 PF06212.7 KEG10368.1 - 0.05 13.3 0.1 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 GRIM-19 protein A_deaminase PF00962.17 KEG10369.1 - 1.7e-106 355.9 0.0 3.4e-64 216.8 0.0 2.4 2 0 0 2 2 2 2 Adenosine/AMP deaminase Chordopox_A33R PF05966.7 KEG10369.1 - 0.14 10.9 0.0 0.25 10.0 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus A33R protein IncA PF04156.9 KEG10369.1 - 1.3 8.6 7.7 3.8 7.0 5.4 1.8 1 0 0 1 1 1 0 IncA protein ADH_N PF08240.7 KEG10370.1 - 2.1e-06 27.4 0.3 3.9e-06 26.5 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEG10370.1 - 0.00011 21.7 0.0 0.00023 20.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2917 PF11142.3 KEG10370.1 - 0.032 13.4 0.0 3.2 6.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2917) TBPIP PF07106.8 KEG10371.1 - 0.019 14.5 0.0 0.04 13.4 0.0 1.5 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) RNB PF00773.14 KEG10372.1 - 9.9e-61 205.7 0.0 1.4e-60 205.2 0.0 1.2 1 0 0 1 1 1 1 RNB domain DUF1413 PF07205.6 KEG10373.1 - 4.5 6.8 6.0 1.8 8.1 0.4 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF1413) DHC_N2 PF08393.8 KEG10374.1 - 7.7e-41 139.9 0.4 2.3e-40 138.3 0.2 1.9 1 1 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_7 PF12775.2 KEG10374.1 - 0.026 13.6 0.0 0.064 12.3 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region D3 ABC_tran PF00005.22 KEG10374.1 - 0.29 11.4 0.0 1.1 9.5 0.0 2.0 1 0 0 1 1 1 0 ABC transporter ATP-synt_ab PF00006.20 KEG10374.1 - 0.35 10.3 0.0 1.6 8.1 0.0 2.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain EXS PF03124.9 KEG10375.1 - 0.045 12.7 0.1 0.048 12.6 0.1 1.1 1 0 0 1 1 1 0 EXS family Kinesin PF00225.18 KEG10377.1 - 0.0082 14.8 0.0 1.8 7.1 0.0 2.9 2 1 0 2 2 2 2 Kinesin motor domain tRNA_lig_kinase PF08303.6 KEG10378.1 - 0.11 12.4 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 tRNA ligase kinase domain Zip PF02535.17 KEG10380.1 - 0.89 8.5 3.3 1.4 7.8 2.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Chorein_N PF12624.2 KEG10382.1 - 2.4e-15 56.1 0.0 8.6e-15 54.3 0.0 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter CENP-B_dimeris PF09026.5 KEG10382.1 - 0.00087 19.4 5.5 0.0019 18.4 3.8 1.4 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Bd3614_N PF14442.1 KEG10382.1 - 0.087 12.8 0.2 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal Nucleoplasmin PF03066.10 KEG10382.1 - 0.089 12.3 9.2 0.34 10.4 4.7 2.2 2 0 0 2 2 2 0 Nucleoplasmin ANAPC15 PF15243.1 KEG10382.1 - 0.12 12.4 5.7 0.25 11.4 3.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 RXT2_N PF08595.6 KEG10382.1 - 0.13 12.0 0.4 0.25 11.1 0.2 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal PUB PF09409.5 KEG10383.1 - 9.8e-11 41.2 0.0 1.8e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 PUB domain DUF572 PF04502.8 KEG10383.1 - 0.15 11.2 2.9 0.19 10.9 2.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Myosin_head PF00063.16 KEG10384.1 - 5.1e-98 328.9 0.0 2.2e-89 300.3 0.0 2.2 2 0 0 2 2 2 2 Myosin head (motor domain) AAA_19 PF13245.1 KEG10384.1 - 0.0014 18.2 3.1 0.0015 18.2 0.2 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 KEG10384.1 - 0.0082 16.1 0.0 0.0082 16.1 0.0 3.2 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.1 KEG10384.1 - 0.037 14.1 0.0 0.15 12.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain Kringle PF00051.13 KEG10385.1 - 1.9e-18 66.3 1.4 4.1e-18 65.2 1.0 1.6 1 0 0 1 1 1 1 Kringle domain CHB_HEX_C PF03174.8 KEG10385.1 - 4.5e-15 55.2 0.4 3.5e-13 49.1 0.1 3.1 2 0 0 2 2 2 1 Chitobiase/beta-hexosaminidase C-terminal domain CHB_HEX_C_1 PF13290.1 KEG10385.1 - 8.1e-13 47.9 0.1 1.9e-11 43.5 0.1 2.9 2 0 0 2 2 2 1 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.1 KEG10385.1 - 4.5e-12 45.8 0.8 8.6e-10 38.5 0.1 3.2 3 0 0 3 3 3 1 Fn3 associated Exostosin PF03016.10 KEG10386.1 - 8.1e-06 25.0 0.0 1.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Exostosin family SEC-C PF02810.10 KEG10387.1 - 0.015 14.7 8.1 0.029 13.9 5.6 1.3 1 0 0 1 1 1 0 SEC-C motif FA_desaturase PF00487.19 KEG10387.1 - 0.023 14.1 0.1 0.031 13.7 0.0 1.1 1 0 0 1 1 1 0 Fatty acid desaturase SAYSvFN PF10260.4 KEG10387.1 - 0.08 12.7 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) DUF2910 PF11139.3 KEG10387.1 - 5.8 5.9 8.0 1.6 7.8 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2910) Glyco_transf_25 PF01755.12 KEG10388.1 - 0.001 18.7 0.0 0.0074 15.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) MMR_HSR1 PF01926.18 KEG10389.1 - 4.1e-14 52.5 0.0 6.7e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KEG10389.1 - 8.3e-10 38.1 0.0 3.7e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KEG10389.1 - 3.2e-05 23.8 0.2 0.016 15.0 0.1 2.3 1 1 1 2 2 2 2 Dynamin family DUF258 PF03193.11 KEG10389.1 - 0.00025 20.2 0.1 0.00044 19.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KEG10389.1 - 0.00068 19.1 0.1 0.041 13.3 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KEG10389.1 - 0.0038 16.4 0.0 0.007 15.6 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_28 PF13521.1 KEG10389.1 - 0.0053 16.7 4.5 0.2 11.5 0.0 3.5 3 2 0 3 3 3 1 AAA domain AAA_21 PF13304.1 KEG10389.1 - 0.024 14.6 0.1 0.036 14.0 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KEG10389.1 - 0.057 13.7 0.0 0.087 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 KEG10389.1 - 0.067 13.6 0.0 0.18 12.3 0.0 1.8 2 0 0 2 2 1 0 Miro-like protein G-alpha PF00503.15 KEG10389.1 - 0.11 11.2 0.0 0.21 10.2 0.0 1.3 1 1 0 1 1 1 0 G-protein alpha subunit AAA_29 PF13555.1 KEG10389.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TFIIB PF00382.14 KEG10390.1 - 1.2e-22 79.4 0.0 3.4e-11 42.7 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 KEG10390.1 - 0.04 13.2 0.0 0.083 12.2 0.0 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding DUF1935 PF09149.5 KEG10391.1 - 2.5e-27 94.8 0.0 2.9e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Raptor_N PF14538.1 KEG10392.1 - 7.1e-16 58.4 0.0 1.9e-15 57.0 0.0 1.7 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain eIF-3_zeta PF05091.7 KEG10392.1 - 0.59 8.6 2.1 0.96 7.9 1.4 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF1935 PF09149.5 KEG10393.1 - 6.9e-12 45.2 0.0 1e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF2413 PF10310.4 KEG10393.1 - 0.0051 15.6 3.4 0.0072 15.1 2.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Daxx PF03344.10 KEG10393.1 - 0.016 13.7 3.9 0.017 13.6 2.7 1.1 1 0 0 1 1 1 0 Daxx Family RR_TM4-6 PF06459.7 KEG10393.1 - 0.75 9.6 4.5 0.92 9.3 3.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1935 PF09149.5 KEG10394.1 - 1.3e-30 105.4 0.1 1.7e-30 105.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) NAP PF00956.13 KEG10395.1 - 3.4e-18 65.6 0.0 5.9e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Ebola_NP PF05505.7 KEG10395.1 - 1.1 7.2 9.0 1.3 7.0 6.3 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Mcp5_PH PF12814.2 KEG10398.1 - 1.2e-13 51.0 0.7 2e-13 50.3 0.5 1.3 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.24 KEG10398.1 - 0.0043 17.2 0.1 0.0079 16.3 0.1 1.4 1 0 0 1 1 1 1 PH domain ACOX PF01756.14 KEG10399.1 - 4.2e-07 29.5 0.0 8.7e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Spt5-NGN PF03439.8 KEG10400.1 - 1.1e-19 69.9 0.2 3.8e-19 68.2 0.0 2.0 2 0 0 2 2 2 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 KEG10400.1 - 1.9e-06 27.3 8.8 0.016 14.9 0.2 4.1 4 0 0 4 4 4 2 KOW motif Spt5_N PF11942.3 KEG10400.1 - 2.3e-05 24.9 1.4 2.3e-05 24.9 0.9 2.8 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal GntR PF00392.16 KEG10400.1 - 0.03 13.7 0.0 0.069 12.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family BUD22 PF09073.5 KEG10400.1 - 1.4 7.9 19.9 2.1 7.3 13.8 1.2 1 0 0 1 1 1 0 BUD22 FLO_LFY PF01698.11 KEG10400.1 - 1.6 7.5 5.0 2.7 6.7 3.5 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Nucleo_P87 PF07267.6 KEG10400.1 - 2.6 6.6 6.2 4.8 5.7 4.3 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 TFIIF_alpha PF05793.7 KEG10400.1 - 3.6 5.8 25.0 5.3 5.2 17.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MORN PF02493.15 KEG10401.1 - 1.3e-14 52.9 20.3 2.1e-06 27.1 0.4 5.2 6 0 0 6 6 6 4 MORN repeat PP2C PF00481.16 KEG10403.1 - 1.8e-75 253.6 0.1 2.2e-75 253.3 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KEG10403.1 - 8.1e-08 31.9 0.0 1.5e-07 31.0 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C YchF-GTPase_C PF06071.8 KEG10404.1 - 5.9e-38 128.5 0.6 1.1e-37 127.6 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 KEG10404.1 - 1.3e-16 60.6 0.0 3.1e-16 59.3 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KEG10404.1 - 0.00024 20.3 0.0 0.00049 19.4 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B ArgK PF03308.11 KEG10404.1 - 0.0034 16.1 0.1 0.0051 15.6 0.1 1.5 1 1 0 1 1 1 1 ArgK protein AAA_17 PF13207.1 KEG10404.1 - 0.0052 17.5 0.1 0.018 15.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain TGS PF02824.16 KEG10404.1 - 0.011 15.5 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 TGS domain AAA_18 PF13238.1 KEG10404.1 - 0.016 15.5 0.0 0.16 12.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain BLOC1_2 PF10046.4 KEG10405.1 - 0.0024 17.9 0.5 0.0046 17.0 0.1 1.6 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 NYD-SP28_assoc PF14775.1 KEG10405.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Sperm tail C-terminal domain Cpn60_TCP1 PF00118.19 KEG10406.1 - 3.7e-07 29.1 0.0 5.2e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ribosomal_L13e PF01294.13 KEG10407.1 - 2.9e-53 179.9 5.3 2.9e-53 179.9 3.7 1.6 1 1 1 2 2 2 1 Ribosomal protein L13e PTPS PF01242.14 KEG10407.1 - 0.046 13.3 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase HSP20 PF00011.16 KEG10408.1 - 1.1e-21 76.6 0.2 1.2e-21 76.4 0.1 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family PDEase_I PF00233.14 KEG10409.1 - 2.1e-60 204.4 1.0 2.1e-60 204.4 0.7 1.4 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Se-cys_synth_N PF12390.3 KEG10409.1 - 0.11 12.5 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 Selenocysteine synthase N terminal Acyltransferase PF01553.16 KEG10413.1 - 1.5e-08 34.1 0.0 3.1e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase EF-hand_7 PF13499.1 KEG10413.1 - 0.00063 19.8 0.1 0.0012 18.9 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KEG10413.1 - 0.0012 17.9 0.0 0.0025 16.9 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 KEG10413.1 - 0.017 14.4 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.1 KEG10413.1 - 0.039 13.5 0.2 0.081 12.5 0.1 1.4 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.1 KEG10413.1 - 0.073 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain SET PF00856.23 KEG10414.1 - 6.6e-07 29.7 0.1 0.0035 17.6 0.0 2.7 2 0 0 2 2 2 2 SET domain NIF PF03031.13 KEG10415.1 - 6.9e-30 103.8 0.0 1.1e-29 103.1 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF705 PF05152.7 KEG10415.1 - 9.4e-05 21.5 0.0 0.00013 21.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF705) PARP PF00644.15 KEG10416.1 - 7.7e-08 32.0 0.0 1.1e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PTS_2-RNA PF01885.11 KEG10416.1 - 0.04 13.2 0.0 0.041 13.1 0.0 1.2 1 0 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family C2 PF00168.25 KEG10417.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 C2 domain Pkinase PF00069.20 KEG10420.1 - 9.3e-48 162.6 0.0 1.3e-47 162.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG10420.1 - 1.1e-31 109.8 0.0 1.5e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG10420.1 - 6.2e-08 31.9 0.0 8.8e-08 31.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEG10420.1 - 0.00082 19.1 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KEG10420.1 - 0.064 12.5 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL IstB_IS21_ATP PF08483.6 KEG10421.1 - 0.93 9.2 3.5 0.93 9.2 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding N-terminal Nol1_Nop2_Fmu PF01189.12 KEG10423.1 - 7.3e-15 55.0 0.0 3.9e-08 33.0 0.0 2.1 2 0 0 2 2 2 2 NOL1/NOP2/sun family PUA PF01472.15 KEG10423.1 - 0.00023 20.7 1.4 0.00067 19.3 1.0 1.8 1 1 0 1 1 1 1 PUA domain Rab3-GTPase_cat PF13890.1 KEG10424.1 - 6.6e-46 155.7 0.0 1.2e-45 154.8 0.0 1.4 1 0 0 1 1 1 1 Rab3 GTPase-activating protein catalytic subunit Abi PF02517.11 KEG10425.1 - 1.7e-16 60.1 0.4 1.2e-15 57.4 0.1 2.4 1 1 0 1 1 1 1 CAAX protease self-immunity MFS_2 PF13347.1 KEG10425.1 - 0.086 11.2 1.7 0.86 7.9 0.5 2.2 2 0 0 2 2 2 0 MFS/sugar transport protein PBP1_TM PF14812.1 KEG10427.1 - 0.17 12.2 4.3 0.59 10.4 3.0 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1292 PF06949.6 KEG10428.1 - 0.027 14.8 0.8 0.13 12.6 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1292) LPAM_2 PF13627.1 KEG10429.1 - 4.6 7.0 7.7 6.9 6.5 0.1 2.7 2 0 0 2 2 2 0 Prokaryotic lipoprotein-attachment site SepQ PF06622.6 KEG10430.1 - 0.08 11.8 0.0 0.091 11.6 0.0 1.0 1 0 0 1 1 1 0 SepQ protein Cys_Met_Meta_PP PF01053.15 KEG10430.1 - 0.1 10.8 0.0 0.11 10.7 0.0 1.0 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme RNase_H2-Ydr279 PF09468.5 KEG10431.1 - 7.3e-19 68.0 0.0 5.3e-18 65.2 0.0 2.0 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) DUF962 PF06127.6 KEG10432.1 - 6.9e-24 83.5 0.3 7.8e-24 83.4 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF962) PMT PF02366.13 KEG10432.1 - 0.012 15.0 1.4 0.014 14.7 1.0 1.0 1 0 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase ATP-synt_C PF00137.16 KEG10432.1 - 0.02 14.7 1.6 0.02 14.7 1.1 1.6 1 1 0 1 1 1 0 ATP synthase subunit C DUF2198 PF09964.4 KEG10432.1 - 0.056 13.2 0.8 0.12 12.1 0.5 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2198) DUF457 PF04307.9 KEG10432.1 - 0.11 11.8 0.5 0.12 11.6 0.4 1.1 1 0 0 1 1 1 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) LRR_6 PF13516.1 KEG10433.1 - 2.4e-13 48.6 18.3 0.57 10.4 0.1 10.8 11 0 0 11 11 11 5 Leucine Rich repeat LRR_4 PF12799.2 KEG10433.1 - 7.8e-08 31.7 4.5 1.6 8.4 0.0 6.7 3 3 3 7 7 7 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEG10433.1 - 8.9e-05 22.0 9.6 26 5.3 0.2 7.8 7 1 0 7 7 7 0 Leucine Rich Repeat LRR_8 PF13855.1 KEG10433.1 - 0.26 11.0 16.4 0.53 10.0 0.1 6.1 5 2 2 7 7 7 0 Leucine rich repeat LRR_7 PF13504.1 KEG10433.1 - 0.59 10.5 12.0 77 4.1 0.0 7.1 9 0 0 9 9 9 0 Leucine rich repeat V_ATPase_I PF01496.14 KEG10433.1 - 1.3 6.7 16.3 2 6.2 11.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Y_phosphatase3C PF13348.1 KEG10434.1 - 0.00023 21.2 0.0 0.00059 19.9 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Terminase_4 PF05119.7 KEG10434.1 - 0.043 13.9 0.1 0.075 13.1 0.0 1.4 1 0 0 1 1 1 0 Phage terminase, small subunit DUF1448 PF07289.6 KEG10436.1 - 1e-130 435.6 0.0 1.2e-130 435.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1448) Pkinase PF00069.20 KEG10437.1 - 2.7e-64 216.8 0.0 3e-64 216.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG10437.1 - 1.5e-44 152.0 0.0 1.8e-44 151.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG10437.1 - 5e-11 42.0 0.0 8.7e-08 31.4 0.0 2.1 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 KEG10437.1 - 1.1e-05 25.2 2.7 0.00024 20.8 0.1 2.5 1 1 2 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 KEG10437.1 - 0.0031 16.6 0.1 0.0048 16.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KEG10437.1 - 0.019 13.8 0.0 0.027 13.2 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 KEG10437.1 - 0.043 13.1 0.0 0.086 12.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Galactosyl_T PF01762.16 KEG10438.1 - 1.9e-05 24.3 0.2 0.054 13.0 0.1 3.4 2 1 1 3 3 3 1 Galactosyltransferase CHORD PF04968.7 KEG10438.1 - 0.14 12.4 0.6 0.8 9.9 0.2 2.1 2 0 0 2 2 2 0 CHORD Aa_trans PF01490.13 KEG10439.1 - 1e-49 169.1 37.7 1.3e-49 168.8 26.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KEG10439.1 - 3.6e-07 29.3 16.0 3.6e-07 29.3 11.1 1.8 1 1 1 2 2 2 1 Tryptophan/tyrosine permease family COX7a PF02238.10 KEG10439.1 - 0.14 11.9 0.5 0.65 9.7 0.3 2.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIa FA_hydroxylase PF04116.8 KEG10440.1 - 2.7e-08 34.2 17.8 2.7e-08 34.2 12.4 2.3 2 2 0 2 2 2 1 Fatty acid hydroxylase superfamily PhaG_MnhG_YufB PF03334.9 KEG10440.1 - 0.087 12.8 4.4 0.32 11.0 0.2 2.4 2 0 0 2 2 2 0 Na+/H+ antiporter subunit Hydrophobin_2 PF06766.6 KEG10441.1 - 0.023 14.3 2.3 2.6 7.8 0.1 2.4 2 0 0 2 2 2 0 Fungal hydrophobin DUF3631 PF12307.3 KEG10441.1 - 0.072 13.0 0.0 3.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3631) Ribosomal_L7Ae PF01248.21 KEG10442.1 - 0.093 12.2 0.0 6.4 6.3 0.0 2.6 2 0 0 2 2 2 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF3658 PF12395.3 KEG10442.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF4381 PF14316.1 KEG10443.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) LRR_4 PF12799.2 KEG10444.1 - 5e-12 45.1 4.0 0.0014 18.2 0.3 4.9 4 1 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEG10444.1 - 1.2e-10 39.9 5.2 0.47 10.6 0.0 7.4 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_8 PF13855.1 KEG10444.1 - 1.6e-08 34.1 3.3 4.7e-05 23.0 1.1 3.6 2 2 1 3 3 3 2 Leucine rich repeat LRR_6 PF13516.1 KEG10444.1 - 0.018 15.0 5.8 1.1e+02 3.3 0.0 6.2 6 2 2 8 8 8 0 Leucine Rich repeat LRR_7 PF13504.1 KEG10444.1 - 0.052 13.7 6.7 18 6.0 0.0 5.9 6 0 0 6 6 6 0 Leucine rich repeat LSM PF01423.17 KEG10445.1 - 1.4e-18 66.1 0.0 1.5e-18 66.0 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KEG10445.1 - 2e-05 24.4 0.0 2.2e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.2 KEG10445.1 - 0.072 12.8 0.0 0.094 12.5 0.0 1.4 1 1 0 1 1 1 0 Scd6-like Sm domain CS PF04969.11 KEG10446.1 - 4.5e-07 30.3 0.6 7.3e-07 29.6 0.4 1.2 1 0 0 1 1 1 1 CS domain ARL2_Bind_BART PF11527.3 KEG10447.1 - 0.011 15.5 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 The ARF-like 2 binding protein BART VLPT PF07122.6 KEG10448.1 - 5.4 6.7 6.7 8.5 6.1 1.0 2.5 2 0 0 2 2 2 0 Variable length PCR target protein (VLPT) CD20 PF04103.10 KEG10448.1 - 6.6 6.6 12.9 3.4 7.6 4.9 2.7 2 1 1 3 3 3 0 CD20-like family zf-Apc11 PF12861.2 KEG10449.1 - 2.4e-33 113.8 11.8 2.7e-33 113.6 8.2 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 KEG10449.1 - 6.6e-28 96.6 13.1 7.3e-28 96.4 9.1 1.0 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KEG10449.1 - 3.6e-06 26.6 22.0 7.4e-06 25.6 14.0 2.5 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KEG10449.1 - 0.00091 18.8 16.6 0.003 17.1 11.2 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEG10449.1 - 0.0022 18.0 10.4 0.0022 18.0 7.2 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEG10449.1 - 0.0037 16.9 19.9 0.25 11.0 13.6 2.3 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KEG10449.1 - 0.0045 16.6 17.8 0.12 12.0 8.2 2.8 1 1 2 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KEG10449.1 - 0.0066 16.2 3.3 0.0066 16.2 2.3 2.6 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 KEG10449.1 - 4.6 6.8 11.1 15 5.2 7.7 2.0 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 KEG10449.1 - 6.8 6.3 23.4 0.041 13.4 2.8 2.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF962 PF06127.6 KEG10451.1 - 5.9e-22 77.3 2.8 2e-21 75.6 1.9 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF962) DUF563 PF04577.9 KEG10453.1 - 5.8e-18 65.5 0.3 6.8e-18 65.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF563) FPL PF09758.4 KEG10454.1 - 3.8e-55 185.7 0.7 6e-55 185.1 0.5 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein Tubulin_C PF03953.12 KEG10457.1 - 0.09 12.8 0.0 0.11 12.4 0.0 1.0 1 0 0 1 1 1 0 Tubulin C-terminal domain LRR_4 PF12799.2 KEG10458.1 - 3.1e-14 52.1 6.3 0.0054 16.3 0.0 5.8 2 1 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG10458.1 - 6.1e-09 35.5 5.4 0.013 15.2 1.0 3.6 1 1 2 4 4 4 4 Leucine rich repeat LRR_6 PF13516.1 KEG10458.1 - 2.7e-05 23.7 9.5 0.2 11.8 0.1 6.4 6 1 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.28 KEG10458.1 - 6.7e-05 22.3 8.6 27 5.3 0.0 7.2 4 2 2 6 6 6 1 Leucine Rich Repeat LRR_7 PF13504.1 KEG10458.1 - 3.2 8.3 14.1 1.4e+02 3.4 0.0 6.9 6 2 2 8 8 8 0 Leucine rich repeat PH PF00169.24 KEG10461.1 - 0.014 15.6 0.7 0.25 11.5 0.0 3.0 3 1 0 3 3 3 0 PH domain DUF4287 PF14117.1 KEG10461.1 - 0.074 12.7 0.1 0.28 10.9 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4287) DOG1 PF14144.1 KEG10461.1 - 4.1 7.5 6.1 42 4.2 0.1 3.7 3 0 0 3 3 3 0 Seed dormancy control Arv1 PF04161.8 KEG10462.1 - 3.3e-22 79.4 4.4 6.6e-22 78.4 3.0 1.5 1 1 0 1 1 1 1 Arv1-like family FAM70 PF14967.1 KEG10462.1 - 0.011 14.9 0.4 0.015 14.4 0.3 1.4 1 0 0 1 1 1 0 FAM70 protein zf-ISL3 PF14690.1 KEG10462.1 - 1.6 8.8 6.2 0.15 12.1 0.5 2.1 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 GSP_synth PF03738.9 KEG10463.1 - 3.4e-23 81.7 0.1 6.2e-23 80.8 0.1 1.4 1 0 0 1 1 1 1 Glutathionylspermidine synthase preATP-grasp CHAP PF05257.11 KEG10463.1 - 1.7e-12 47.0 0.0 3.4e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 CHAP domain CP_ATPgrasp_2 PF14403.1 KEG10463.1 - 0.0045 15.6 0.0 0.0073 15.0 0.0 1.2 1 0 0 1 1 1 1 Circularly permuted ATP-grasp type 2 Ceramidase PF05875.7 KEG10464.1 - 0.0071 15.5 0.0 0.008 15.3 0.0 1.0 1 0 0 1 1 1 1 Ceramidase PsaX PF08078.7 KEG10464.1 - 0.021 14.7 3.5 0.031 14.1 2.4 1.3 1 0 0 1 1 1 0 PsaX family F-box-like PF12937.2 KEG10464.1 - 0.061 13.0 0.5 0.34 10.6 0.2 2.1 2 0 0 2 2 2 0 F-box-like Pkinase PF00069.20 KEG10465.1 - 7.3e-56 189.1 0.0 1.4e-49 168.6 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEG10465.1 - 3.8e-24 85.1 0.0 2.8e-20 72.4 0.0 2.4 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 KEG10465.1 - 9.4e-06 25.5 0.0 1.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KEG10465.1 - 0.00052 19.0 0.0 0.001 18.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KEG10465.1 - 0.0068 15.4 0.1 0.016 14.3 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KEG10465.1 - 0.14 11.6 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase P5CR_dimer PF14748.1 KEG10466.1 - 1.5e-40 137.5 3.3 2.6e-40 136.7 2.3 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 KEG10466.1 - 9.2e-21 74.0 0.0 2.6e-20 72.6 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 KEG10466.1 - 4.7e-08 33.0 1.5 5.6e-08 32.7 0.1 1.9 2 2 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 KEG10466.1 - 5.6e-05 23.2 0.0 0.00012 22.1 0.0 1.8 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.17 KEG10466.1 - 0.0013 19.2 0.4 0.0041 17.6 0.0 2.0 2 1 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_Gly3P_dh_N PF01210.18 KEG10466.1 - 0.0087 15.7 2.0 0.017 14.8 1.4 1.7 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 KEG10466.1 - 0.011 15.2 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AA_permease_2 PF13520.1 KEG10466.1 - 0.059 11.8 0.6 0.074 11.5 0.4 1.2 1 0 0 1 1 1 0 Amino acid permease Med26 PF08711.6 KEG10467.1 - 0.0058 16.1 1.6 0.078 12.4 0.0 2.4 2 0 0 2 2 2 1 TFIIS helical bundle-like domain FLO_LFY PF01698.11 KEG10467.1 - 0.93 8.2 12.7 2 7.1 8.8 1.6 1 0 0 1 1 1 0 Floricaula / Leafy protein AAA_19 PF13245.1 KEG10468.1 - 2.5e-05 23.9 2.5 2.9e-05 23.7 0.1 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 KEG10468.1 - 0.0022 17.8 0.2 0.0067 16.3 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEG10468.1 - 0.0029 18.4 0.1 0.005 17.6 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KEG10468.1 - 0.0048 16.3 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KEG10468.1 - 0.011 14.9 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 KaiC DnaB_C PF03796.10 KEG10468.1 - 0.022 13.6 0.0 0.033 13.0 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Zeta_toxin PF06414.7 KEG10468.1 - 0.044 12.8 0.1 0.093 11.8 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.1 KEG10468.1 - 0.064 13.4 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KEG10468.1 - 0.089 12.9 0.0 0.37 10.9 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KEG10468.1 - 0.096 12.3 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 KEG10468.1 - 0.18 12.1 0.0 0.41 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain RabGAP-TBC PF00566.13 KEG10469.1 - 3.2e-41 141.1 5.3 4.6e-41 140.6 3.6 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 KEG10469.1 - 1.2e-07 31.2 0.0 2.3e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3548) Rotamase PF00639.16 KEG10470.1 - 2.2e-19 69.9 0.0 2.2e-19 69.9 0.0 2.4 2 1 0 2 2 2 1 PPIC-type PPIASE domain FHA PF00498.21 KEG10470.1 - 1.5e-17 63.4 0.0 2.5e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 FHA domain Rotamase_3 PF13616.1 KEG10470.1 - 2.4e-10 40.6 0.0 6.6e-10 39.2 0.0 1.8 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 KEG10470.1 - 0.0056 17.2 10.5 0.069 13.7 5.8 2.8 2 1 0 2 2 2 1 PPIC-type PPIASE domain PPR PF01535.15 KEG10471.1 - 2.9e-05 23.7 0.2 3 8.0 0.2 4.7 4 0 0 4 4 4 2 PPR repeat Apc3 PF12895.2 KEG10471.1 - 0.026 14.6 3.7 0.051 13.7 0.0 3.3 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR_2 PF13041.1 KEG10471.1 - 0.11 12.4 0.6 15 5.6 0.3 2.9 3 0 0 3 3 3 0 PPR repeat family PPR_3 PF13812.1 KEG10471.1 - 0.49 10.8 9.1 30 5.2 0.1 6.1 6 0 0 6 6 6 0 Pentatricopeptide repeat domain TPR_14 PF13428.1 KEG10471.1 - 2.3 9.1 20.2 5.8 7.8 0.0 7.1 7 1 1 8 8 8 0 Tetratricopeptide repeat Kinesin PF00225.18 KEG10472.1 - 5.3e-86 288.3 2.2 5.3e-86 288.3 1.5 1.8 2 0 0 2 2 2 1 Kinesin motor domain Uds1 PF15456.1 KEG10472.1 - 0.37 10.7 30.6 0.015 15.3 6.4 4.7 3 1 0 4 4 4 0 Up-regulated During Septation YojJ PF10372.4 KEG10472.1 - 0.65 9.9 5.0 0.58 10.0 0.4 3.0 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus LRR_4 PF12799.2 KEG10473.1 - 4.7e-19 67.5 12.8 1e-10 41.0 2.0 3.4 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 KEG10473.1 - 1e-09 38.2 0.5 2e-05 24.2 0.2 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.1 KEG10473.1 - 2.7e-08 33.4 9.2 0.00042 20.0 2.3 2.9 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 KEG10473.1 - 2.1e-06 26.9 3.8 1.8 8.8 0.2 4.8 3 2 1 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 KEG10473.1 - 9.8e-05 21.9 4.6 11 6.7 0.0 5.1 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 KEG10473.1 - 0.0014 18.5 13.7 1.6 9.0 0.1 4.9 5 1 1 6 6 6 2 Leucine Rich repeat DUF1193 PF06702.7 KEG10474.1 - 0.046 13.1 0.2 0.081 12.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1193) SNF2_N PF00176.18 KEG10475.1 - 9.7e-41 139.4 0.0 1.5e-40 138.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEG10475.1 - 4.9e-11 42.3 0.0 1.8e-10 40.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEG10475.1 - 3.4e-06 26.9 0.0 8.6e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KEG10475.1 - 0.072 12.5 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase Spt20 PF12090.3 KEG10476.1 - 0.22 10.8 4.2 1.3 8.3 1.8 2.2 2 0 0 2 2 2 0 Spt20 family DnaJ PF00226.26 KEG10477.1 - 9.3e-16 57.3 0.0 5e-15 54.9 0.0 2.2 2 0 0 2 2 2 1 DnaJ domain DUF4231 PF14015.1 KEG10478.1 - 1.3 9.0 4.4 1.3 9.0 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Clathrin_lg_ch PF01086.12 KEG10479.1 - 9.9e-08 32.1 8.3 1.7e-07 31.4 5.8 1.4 1 1 0 1 1 1 1 Clathrin light chain Birna_VP4 PF01768.11 KEG10479.1 - 0.037 13.0 0.6 0.049 12.6 0.4 1.2 1 0 0 1 1 1 0 Birnavirus VP4 protein DUF2526 PF10735.4 KEG10479.1 - 9.1 6.3 8.4 0.33 10.9 0.8 2.4 3 1 0 3 3 3 0 Protein of unknown function (DUF2526) SNARE PF05739.14 KEG10480.1 - 1e-08 34.7 1.9 1e-08 34.7 1.3 2.3 3 0 0 3 3 3 1 SNARE domain Synaptobrevin PF00957.16 KEG10480.1 - 0.0064 16.0 0.2 0.013 15.1 0.1 1.6 1 0 0 1 1 1 1 Synaptobrevin TMEM154 PF15102.1 KEG10480.1 - 0.015 14.9 0.2 0.028 14.1 0.2 1.5 1 0 0 1 1 1 0 TMEM154 protein family Use1 PF09753.4 KEG10480.1 - 0.018 14.4 4.9 0.039 13.3 3.4 1.5 1 1 0 1 1 1 0 Membrane fusion protein Use1 DUF2116 PF09889.4 KEG10480.1 - 0.034 13.9 1.0 0.096 12.4 0.7 1.8 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF912 PF06024.7 KEG10480.1 - 0.18 11.8 1.5 0.19 11.8 0.2 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Shisa PF13908.1 KEG10480.1 - 0.27 11.4 1.5 0.49 10.5 0.7 1.7 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF4398 PF14346.1 KEG10480.1 - 0.67 10.0 7.2 0.085 12.9 1.3 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4398) Rifin_STEVOR PF02009.11 KEG10480.1 - 0.75 9.3 8.2 1.7 8.1 5.7 1.8 1 1 0 1 1 1 0 Rifin/stevor family MscS_porin PF12795.2 KEG10480.1 - 5.7 6.1 6.7 7.6 5.7 0.3 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Pkinase PF00069.20 KEG10481.1 - 8.8e-54 182.3 0.0 1.6e-53 181.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG10481.1 - 1.6e-25 89.7 0.0 1.6e-20 73.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase CAP_GLY PF01302.20 KEG10481.1 - 1.6e-16 59.7 1.1 2.9e-16 58.9 0.8 1.5 1 0 0 1 1 1 1 CAP-Gly domain Kinase-like PF14531.1 KEG10481.1 - 1.7e-06 27.2 0.0 0.0033 16.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase PF00069.20 KEG10482.1 - 3.6e-55 186.9 0.0 4.1e-55 186.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG10482.1 - 1e-32 113.2 0.0 1.3e-32 112.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase TruB_C PF09142.6 KEG10482.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal Peptidase_M24 PF00557.19 KEG10483.1 - 1.5e-34 119.4 0.8 2e-34 119.0 0.5 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 nsp8 PF08717.5 KEG10483.1 - 0.018 14.6 0.1 0.034 13.7 0.1 1.4 1 0 0 1 1 1 0 nsp8 replicase Pkinase PF00069.20 KEG10485.1 - 1.6e-73 247.0 0.0 1.9e-73 246.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG10485.1 - 1.5e-31 109.4 0.0 1.1e-30 106.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEG10485.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family HTH_3 PF01381.17 KEG10486.1 - 1e-11 44.4 0.0 1.5e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 KEG10486.1 - 3.5e-07 30.3 0.7 5.7e-07 29.6 0.5 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain MBF1 PF08523.5 KEG10486.1 - 2.3e-06 27.5 1.0 2.3e-06 27.5 0.7 2.0 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_19 PF12844.2 KEG10486.1 - 0.00011 22.1 0.0 0.00019 21.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.1 KEG10486.1 - 0.027 14.1 0.1 0.038 13.6 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_37 PF13744.1 KEG10486.1 - 0.065 13.0 0.3 0.13 12.1 0.2 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain SecY PF00344.15 KEG10487.1 - 1.8e-72 244.2 6.5 2.2e-72 243.8 4.5 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 KEG10487.1 - 7.6e-17 60.5 0.1 1.6e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 Plug domain of Sec61p RRM_6 PF14259.1 KEG10488.1 - 0.0067 16.3 0.0 5.9 6.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEG10488.1 - 0.012 15.2 0.0 4.2 7.0 0.0 2.7 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Imm35 PF15581.1 KEG10489.1 - 0.052 13.5 0.1 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 Immunity protein 35 DUF4071 PF13281.1 KEG10489.1 - 0.1 11.4 0.1 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) Exo_endo_phos PF03372.18 KEG10491.1 - 1.4e-08 35.0 0.0 2.7e-08 34.0 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PEP-utilizers_C PF02896.13 KEG10492.1 - 2e-100 335.4 0.0 3.2e-100 334.8 0.0 1.3 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.14 KEG10492.1 - 2.7e-62 210.7 0.0 5.7e-62 209.6 0.0 1.5 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.18 KEG10492.1 - 1.7e-22 78.7 0.1 4.1e-22 77.5 0.1 1.7 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain HTH_24 PF13412.1 KEG10492.1 - 0.13 11.6 0.1 0.34 10.3 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding IQ PF00612.22 KEG10493.1 - 0.00011 21.5 0.7 0.00033 20.0 0.5 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif AdoHcyase_NAD PF00670.16 KEG10493.1 - 0.089 12.6 0.1 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain FOP_dimer PF09398.5 KEG10496.1 - 7.4e-09 35.4 0.0 1.5e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 FOP N terminal dimerisation domain LisH PF08513.6 KEG10496.1 - 0.0086 15.8 0.4 0.022 14.4 0.3 1.7 1 0 0 1 1 1 1 LisH Snf7 PF03357.16 KEG10497.1 - 8.5e-18 64.3 14.2 8.5e-18 64.3 9.8 1.3 1 1 0 1 1 1 1 Snf7 Ist1 PF03398.9 KEG10497.1 - 0.0088 15.4 4.0 0.062 12.6 2.7 2.0 1 1 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DUF3365 PF11845.3 KEG10497.1 - 0.28 11.0 4.2 0.24 11.2 1.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3365) CAF1C_H4-bd PF12265.3 KEG10498.1 - 8.9e-18 63.9 0.1 1.9e-17 62.8 0.1 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.27 KEG10498.1 - 0.0012 18.6 15.0 0.0029 17.4 0.1 4.2 5 0 0 5 5 5 2 WD domain, G-beta repeat Pho88 PF10032.4 KEG10499.1 - 1.2e-46 158.3 0.0 1.5e-46 158.0 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) She9_MDM33 PF05546.6 KEG10501.1 - 0.093 12.2 0.2 0.1 12.1 0.1 1.0 1 0 0 1 1 1 0 She9 / Mdm33 family Pkinase PF00069.20 KEG10504.1 - 1.6e-59 201.1 0.0 2.2e-59 200.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG10504.1 - 1.8e-27 96.0 0.0 2.3e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEG10504.1 - 1.1e-06 28.5 0.0 2.2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KEG10504.1 - 5.7e-06 25.4 0.0 9.7e-06 24.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 KEG10504.1 - 0.0032 17.0 0.0 0.0049 16.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 KEG10504.1 - 0.0043 16.1 0.0 0.0068 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KEG10504.1 - 0.053 12.3 0.0 0.077 11.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase D123 PF07065.9 KEG10505.1 - 1.7e-09 37.1 0.0 3.3e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 D123 DUF3584 PF12128.3 KEG10506.1 - 0.0003 18.3 36.4 0.0003 18.3 25.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3584) GRIM-19 PF06212.7 KEG10507.1 - 4.9e-09 35.9 0.1 5.9e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 GRIM-19 protein DPCD PF14913.1 KEG10508.1 - 4.8e-48 162.8 0.8 6e-48 162.5 0.5 1.0 1 0 0 1 1 1 1 DPCD protein family RNA_pol_L_2 PF13656.1 KEG10509.1 - 2.9e-26 90.6 0.0 4.3e-26 90.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KEG10509.1 - 1.6e-05 23.8 0.0 2.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Sua5_yciO_yrdC PF01300.13 KEG10510.1 - 6.1e-50 168.9 0.0 9e-50 168.3 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 KEG10510.1 - 7e-08 32.5 0.0 1e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding DEAD PF00270.24 KEG10511.1 - 2.8e-44 150.5 0.0 2.8e-43 147.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEG10511.1 - 3.6e-26 90.8 0.6 1.4e-25 88.9 0.4 2.0 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEG10511.1 - 3.2e-07 30.3 0.0 8e-07 29.0 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.9 KEG10511.1 - 0.0023 16.5 0.0 0.0039 15.8 0.0 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer AAA_19 PF13245.1 KEG10511.1 - 0.087 12.5 0.2 0.25 11.1 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain CEP76-C2 PF15627.1 KEG10512.1 - 5.6e-38 129.9 0.0 8.3e-38 129.3 0.0 1.3 1 0 0 1 1 1 1 CEP76 C2 domain UPF0220 PF05255.6 KEG10513.1 - 4e-14 52.2 1.4 4.3e-14 52.1 1.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF4131 PF13567.1 KEG10513.1 - 0.00082 18.8 0.3 0.00082 18.8 0.2 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4131) FxsA PF04186.8 KEG10513.1 - 0.042 13.4 3.0 0.063 12.8 0.2 2.3 2 1 1 3 3 3 0 FxsA cytoplasmic membrane protein DctQ PF04290.7 KEG10513.1 - 0.56 9.9 12.4 0.41 10.4 1.2 2.0 1 1 1 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF202 PF02656.10 KEG10513.1 - 1.3 9.3 5.9 6.9 6.9 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF202) PrgI PF12666.2 KEG10513.1 - 4.2 7.5 9.4 2.3 8.4 0.2 2.1 2 0 0 2 2 2 0 PrgI family protein GDPD PF03009.12 KEG10514.1 - 1.8e-19 70.2 0.0 5.5e-16 58.8 0.0 2.1 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family Ax_dynein_light PF10211.4 KEG10516.1 - 4e-81 271.3 13.3 5.1e-81 271.0 9.2 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain ERM PF00769.14 KEG10516.1 - 0.00077 19.0 14.1 0.0015 18.1 9.8 1.5 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Syntaxin-6_N PF09177.6 KEG10516.1 - 0.0016 18.8 3.8 0.0044 17.3 2.6 1.9 1 0 0 1 1 1 1 Syntaxin 6, N-terminal Spc24 PF08286.6 KEG10516.1 - 0.0031 17.2 5.7 0.0064 16.1 4.0 1.5 1 0 0 1 1 1 1 Spc24 subunit of Ndc80 CENP-F_leu_zip PF10473.4 KEG10516.1 - 0.011 15.5 12.5 0.011 15.5 8.7 1.9 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3373 PF11853.3 KEG10516.1 - 0.023 13.2 2.3 0.033 12.7 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) IncA PF04156.9 KEG10516.1 - 0.054 13.1 21.2 0.3 10.6 14.6 2.0 1 1 0 1 1 1 0 IncA protein Prefoldin PF02996.12 KEG10516.1 - 0.15 11.6 8.5 3.6 7.2 2.0 2.7 2 1 1 3 3 2 0 Prefoldin subunit DUF342 PF03961.8 KEG10516.1 - 0.19 10.0 2.7 0.28 9.5 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Siah-Interact_N PF09032.6 KEG10516.1 - 0.22 11.5 10.9 5.6 7.0 0.0 3.0 2 1 1 3 3 3 0 Siah interacting protein, N terminal APG6 PF04111.7 KEG10516.1 - 0.3 10.1 17.2 0.15 11.0 10.5 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 KEG10516.1 - 0.63 8.9 8.1 0.88 8.4 5.6 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF947 PF06102.7 KEG10516.1 - 0.64 9.8 11.8 0.1 12.3 5.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF947) UreF PF01730.11 KEG10516.1 - 0.75 9.8 4.6 2.5 8.1 1.8 2.1 2 0 0 2 2 2 0 UreF L_lactis_ph-MCP PF06673.6 KEG10516.1 - 1 8.0 5.0 1.8 7.2 3.4 1.3 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein Mnd1 PF03962.10 KEG10516.1 - 1.1 8.9 12.0 0.25 10.9 6.2 1.5 2 0 0 2 2 2 0 Mnd1 family CENP-Q PF13094.1 KEG10516.1 - 1.2 9.1 13.4 1 9.3 8.0 1.8 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit V_ATPase_I PF01496.14 KEG10516.1 - 1.2 6.9 4.2 1.4 6.6 2.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4164 PF13747.1 KEG10516.1 - 1.9 8.6 16.2 0.49 10.5 7.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) DUF4337 PF14235.1 KEG10516.1 - 1.9 8.3 6.5 3.6 7.4 4.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Nsp1_C PF05064.8 KEG10516.1 - 2 8.1 9.2 1.4 8.6 4.8 1.9 2 1 0 2 2 2 0 Nsp1-like C-terminal region DivIC PF04977.10 KEG10516.1 - 2 7.9 10.5 3.9 7.0 5.6 2.4 2 0 0 2 2 2 0 Septum formation initiator DUF3782 PF12644.2 KEG10516.1 - 6.2 6.6 7.7 4.5 7.1 1.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3782) CAF-1_p150 PF11600.3 KEG10516.1 - 6.2 6.1 20.9 0.4 10.0 10.8 1.6 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal OmpH PF03938.9 KEG10516.1 - 7.1 6.5 15.4 15 5.5 10.7 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) RGS-like PF09128.6 KEG10516.1 - 9.5 5.6 9.6 15 5.0 6.0 2.0 1 1 0 1 1 1 0 Regulator of G protein signalling-like domain TIM PF00121.13 KEG10517.1 - 1.9e-87 292.4 0.1 2.1e-87 292.2 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Glycos_transf_N PF04413.11 KEG10518.1 - 0.089 11.9 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) EMP24_GP25L PF01105.19 KEG10519.1 - 1.6e-14 54.0 0.0 2.3e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2339 PF10101.4 KEG10520.1 - 0.066 11.4 0.0 0.079 11.2 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) P12 PF12669.2 KEG10520.1 - 0.28 11.4 1.4 0.3 11.2 0.3 1.6 2 0 0 2 2 2 0 Virus attachment protein p12 family DNA_pol_A PF00476.15 KEG10521.1 - 2.3e-35 121.9 0.0 4.7e-35 120.9 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family A DUF4612 PF15389.1 KEG10521.1 - 1.1 9.8 8.1 0.7 10.5 3.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4612) MCM PF00493.18 KEG10523.1 - 8e-121 402.8 0.1 1.3e-120 402.1 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KEG10523.1 - 1.8e-15 57.5 0.0 6.2e-15 55.7 0.0 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KEG10523.1 - 6.1e-07 28.8 0.0 6e-06 25.5 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KEG10523.1 - 0.00053 19.7 0.0 0.0032 17.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KEG10523.1 - 0.00064 19.3 0.0 0.0015 18.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PUA PF01472.15 KEG10523.1 - 0.023 14.3 2.1 4.6 7.0 0.1 2.5 2 0 0 2 2 2 0 PUA domain Sigma54_activat PF00158.21 KEG10523.1 - 0.043 13.2 0.0 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain tRNA_anti_2 PF13742.1 KEG10523.1 - 0.097 12.5 0.2 2.1 8.2 0.0 2.8 3 0 0 3 3 3 0 OB-fold nucleic acid binding domain MTS PF05175.9 KEG10524.1 - 0.00063 19.1 0.1 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 KEG10524.1 - 0.0011 19.4 0.0 0.0022 18.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KEG10524.1 - 0.012 15.2 0.1 0.017 14.7 0.1 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase PQQ_3 PF13570.1 KEG10524.1 - 0.018 15.3 0.7 0.55 10.5 0.2 2.5 2 0 0 2 2 2 0 PQQ-like domain Methyltransf_12 PF08242.7 KEG10524.1 - 0.02 15.3 2.1 0.073 13.5 0.0 2.6 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_25 PF13649.1 KEG10524.1 - 0.041 14.2 0.1 0.075 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KEG10524.1 - 0.043 14.4 0.2 0.1 13.1 0.1 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 KEG10524.1 - 0.072 12.6 0.0 0.19 11.3 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Mito_carr PF00153.22 KEG10525.1 - 1e-19 70.0 0.1 1.2e-19 69.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial carrier protein Mito_carr PF00153.22 KEG10526.1 - 1.9e-34 117.2 0.4 1.2e-21 76.1 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein DSPc PF00782.15 KEG10528.1 - 1.8e-09 37.2 0.0 3e-09 36.5 0.0 1.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KEG10528.1 - 3.4e-06 26.5 0.0 6.7e-06 25.6 0.0 1.4 1 1 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 KEG10528.1 - 0.095 12.1 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Mid2 PF04478.7 KEG10528.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DSPc PF00782.15 KEG10529.1 - 1.2e-08 34.6 0.0 2.2e-08 33.7 0.0 1.5 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KEG10529.1 - 1e-06 28.2 0.0 5.2e-06 25.9 0.0 1.9 1 1 1 2 2 2 1 Protein-tyrosine phosphatase Abhydrolase_5 PF12695.2 KEG10530.1 - 0.00052 19.7 0.0 0.00064 19.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family FHA PF00498.21 KEG10531.1 - 1.1e-13 51.0 0.0 2.6e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 FHA domain Mucin PF01456.12 KEG10532.1 - 0.00091 19.0 11.9 0.03 14.1 4.3 2.5 2 0 0 2 2 2 2 Mucin-like glycoprotein DUF2009 PF09418.5 KEG10532.1 - 0.0073 15.1 3.8 0.012 14.4 2.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) DUF1664 PF07889.7 KEG10532.1 - 0.057 13.2 8.1 0.81 9.4 2.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CesA PF11439.3 KEG10532.1 - 0.4 10.6 9.4 0.037 13.9 2.1 2.4 2 1 2 4 4 4 0 Type III secretion system filament chaperone CesA DUF948 PF06103.6 KEG10532.1 - 1.8 8.4 6.9 0.38 10.6 0.8 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Flu_M1_C PF08289.6 KEG10532.1 - 2.4 8.2 8.1 0.19 11.8 0.3 3.0 3 0 0 3 3 3 0 Influenza Matrix protein (M1) C-terminal domain AAA_13 PF13166.1 KEG10532.1 - 3.7 5.9 21.7 0.37 9.2 5.2 2.1 2 0 0 2 2 2 0 AAA domain DUF2201_N PF13203.1 KEG10533.1 - 3.8 6.5 8.7 5.2 6.1 6.1 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain UCH PF00443.24 KEG10535.1 - 9e-60 202.0 0.1 1.8e-59 201.1 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEG10535.1 - 2e-25 89.8 0.1 2.8e-25 89.3 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Sgf11 PF08209.6 KEG10535.1 - 0.1 11.9 2.2 0.25 10.6 0.2 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) NACHT PF05729.7 KEG10535.1 - 0.13 11.9 0.1 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain zf-C2HC_2 PF13913.1 KEG10535.1 - 4.2 7.1 6.1 1.4 8.6 0.1 2.9 3 1 0 3 3 3 0 zinc-finger of a C2HC-type SNAPc19 PF15497.1 KEG10536.1 - 0.061 13.5 4.7 0.088 13.0 0.3 2.5 2 0 0 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Ribonucleas_3_3 PF14622.1 KEG10537.1 - 5.7e-09 36.0 0.1 7.1e-08 32.4 0.1 2.1 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 KEG10537.1 - 0.0055 17.1 0.0 0.013 15.9 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease III domain LRR_6 PF13516.1 KEG10538.1 - 7e-18 62.6 11.0 0.038 14.0 0.1 9.9 10 0 0 10 10 10 4 Leucine Rich repeat LRR_4 PF12799.2 KEG10538.1 - 1.1e-11 44.0 0.4 0.046 13.3 0.0 5.5 4 1 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEG10538.1 - 6.8e-09 34.5 0.5 25 5.4 0.0 8.1 8 1 0 8 8 8 1 Leucine Rich Repeat LRR_8 PF13855.1 KEG10538.1 - 4.7e-05 23.0 3.1 2.5 7.8 0.8 5.1 4 1 0 4 4 4 2 Leucine rich repeat LRR_7 PF13504.1 KEG10538.1 - 0.00017 21.2 10.3 61 4.4 0.0 7.3 7 0 0 7 7 7 0 Leucine rich repeat KAP PF05804.7 KEG10539.1 - 0.062 11.2 0.0 0.093 10.6 0.0 1.2 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) zf-CCCH PF00642.19 KEG10540.1 - 0.00026 20.5 5.6 0.00046 19.7 3.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Helicase_C PF00271.26 KEG10540.1 - 0.00053 19.8 0.0 0.0081 15.9 0.0 2.6 1 1 0 1 1 1 1 Helicase conserved C-terminal domain zf-CCCH_2 PF14608.1 KEG10540.1 - 0.068 13.1 5.7 0.15 12.0 3.9 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type KH_1 PF00013.24 KEG10540.1 - 0.095 12.3 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 KH domain tRNA-synt_1d PF00750.14 KEG10541.1 - 1.1e-90 304.0 0.0 1.6e-52 178.4 0.0 2.4 1 1 1 3 3 3 2 tRNA synthetases class I (R) DALR_1 PF05746.10 KEG10541.1 - 4.1e-24 84.8 0.4 1.6e-22 79.7 0.0 2.7 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 KEG10541.1 - 1.2e-13 51.4 0.0 5.3e-13 49.3 0.0 2.2 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.14 KEG10541.1 - 0.035 13.2 0.0 0.066 12.3 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Cupin_8 PF13621.1 KEG10542.1 - 8.3e-17 61.5 0.0 4.8e-16 59.0 0.0 2.2 2 1 0 2 2 2 1 Cupin-like domain JmjC PF02373.17 KEG10542.1 - 4.2e-09 36.6 0.1 8.7e-09 35.6 0.1 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase F-box PF00646.28 KEG10542.1 - 2.4e-05 23.8 0.3 5.7e-05 22.6 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KEG10542.1 - 0.00018 21.1 1.4 0.00042 19.9 1.0 1.6 1 0 0 1 1 1 1 F-box-like Cupin_4 PF08007.7 KEG10542.1 - 0.00066 19.0 0.0 0.0016 17.7 0.0 1.6 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.6 KEG10542.1 - 0.051 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Mo25 PF08569.6 KEG10543.1 - 0.02 13.9 0.3 0.033 13.2 0.2 1.2 1 0 0 1 1 1 0 Mo25-like DUF2802 PF10975.3 KEG10543.1 - 0.099 12.4 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) zf-C4H2 PF10146.4 KEG10544.1 - 0.077 12.9 3.5 0.19 11.7 0.6 2.0 2 0 0 2 2 2 0 Zinc finger-containing protein Ecotin PF03974.8 KEG10546.1 - 8.8e-41 138.6 0.0 1.1e-40 138.3 0.0 1.0 1 0 0 1 1 1 1 Ecotin AAA PF00004.24 KEG10547.1 - 5e-38 130.2 0.0 9.6e-38 129.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 KEG10547.1 - 2.2e-07 30.6 0.0 7.1e-07 29.0 0.0 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.7 KEG10547.1 - 5.9e-07 28.7 0.0 3.1e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KEG10547.1 - 6.6e-06 26.2 0.1 0.00017 21.7 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KEG10547.1 - 8e-06 25.6 0.1 3.8e-05 23.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KEG10547.1 - 0.0001 23.0 0.0 0.00022 22.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEG10547.1 - 0.00051 19.7 1.7 0.0021 17.7 0.0 2.9 3 1 0 3 3 2 1 Part of AAA domain TIP49 PF06068.8 KEG10547.1 - 0.00061 18.6 0.0 0.0012 17.6 0.0 1.4 1 1 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 KEG10547.1 - 0.00063 19.1 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 KEG10547.1 - 0.00097 19.0 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KEG10547.1 - 0.0017 18.3 1.3 0.0085 16.0 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.16 KEG10547.1 - 0.0038 16.4 0.0 0.01 15.0 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 KEG10547.1 - 0.0047 16.8 0.1 0.021 14.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KEG10547.1 - 0.005 15.9 0.0 0.014 14.4 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 KEG10547.1 - 0.0052 16.2 0.2 0.24 10.7 0.0 2.5 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.8 KEG10547.1 - 0.017 14.0 0.0 0.029 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 KEG10547.1 - 0.02 14.8 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 KEG10547.1 - 0.041 13.4 0.0 0.078 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 KEG10547.1 - 0.057 12.2 0.0 0.087 11.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_18 PF13238.1 KEG10547.1 - 0.074 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KEG10547.1 - 0.13 12.3 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Mito_fiss_reg PF05308.6 KEG10548.1 - 0.0019 17.5 3.6 0.0044 16.4 2.5 1.5 1 0 0 1 1 1 1 Mitochondrial fission regulator zf-ISL3 PF14690.1 KEG10550.1 - 5.3 7.1 9.1 1.7 8.7 0.5 3.3 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 RRM_1 PF00076.17 KEG10551.1 - 1e-21 76.3 0.0 3e-14 52.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG10551.1 - 6.5e-17 61.2 0.0 1.1e-11 44.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG10551.1 - 6.7e-08 32.2 0.0 1e-06 28.4 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KEG10551.1 - 0.00082 19.0 0.9 0.015 15.0 0.2 2.7 2 1 0 2 2 2 1 Limkain b1 Ribosomal_L44 PF00935.14 KEG10552.1 - 7.4e-32 109.1 7.7 1.1e-31 108.6 5.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 RNHCP PF12647.2 KEG10552.1 - 0.4 10.5 2.4 2.1 8.2 1.7 2.0 1 1 0 1 1 1 0 RNHCP domain DUF1018 PF06252.7 KEG10553.1 - 1 9.8 5.4 1.6 9.2 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) ABC_tran PF00005.22 KEG10555.1 - 2.6e-23 82.8 0.0 6e-23 81.6 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 KEG10555.1 - 0.00024 20.4 0.0 0.0003 20.0 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KEG10555.1 - 0.0054 17.5 0.0 0.038 14.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEG10555.1 - 0.012 15.6 0.0 0.033 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.1 KEG10555.1 - 0.014 15.3 0.8 0.29 11.0 0.5 2.2 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KEG10555.1 - 0.059 13.6 0.0 0.18 12.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KEG10555.1 - 0.081 12.1 0.0 0.45 9.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Adaptin_binding PF10199.4 KEG10557.1 - 4.9e-09 36.5 4.0 0.014 15.6 3.3 4.0 3 1 0 3 3 3 3 Alpha and gamma adaptin binding protein p34 HTH_Tnp_Tc5 PF03221.11 KEG10557.1 - 0.045 13.5 0.3 0.1 12.4 0.2 1.6 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain Med3 PF11593.3 KEG10558.1 - 0.4 9.8 4.0 0.69 9.0 2.8 1.4 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal RNA_pol PF00940.14 KEG10559.1 - 5.5e-126 420.3 0.0 8e-126 419.7 0.0 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase Phage_int_SAM_2 PF12834.2 KEG10559.1 - 0.027 14.8 1.7 4.9 7.6 0.2 3.1 3 0 0 3 3 3 0 Phage integrase, N-terminal fn3 PF00041.16 KEG10560.1 - 1.4e-17 63.5 0.3 2.5e-06 27.5 0.0 5.4 5 0 0 5 5 5 4 Fibronectin type III domain EF-hand_8 PF13833.1 KEG10561.1 - 8.8e-05 22.0 0.0 0.02 14.5 0.0 1.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KEG10561.1 - 9.3e-05 21.4 0.0 0.04 13.2 0.0 2.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KEG10561.1 - 0.00036 20.1 0.0 0.065 13.1 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 KEG10561.1 - 0.0076 16.3 0.1 0.045 13.8 0.0 1.9 1 1 0 1 1 1 1 EF-hand domain pair Peptidase_S9 PF00326.16 KEG10562.1 - 0.00013 21.2 0.2 0.0093 15.1 0.0 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KEG10562.1 - 0.0014 18.0 0.1 0.0046 16.4 0.0 1.8 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.8 KEG10562.1 - 0.0044 16.4 0.2 0.016 14.6 0.0 1.9 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Esterase PF00756.15 KEG10562.1 - 0.0054 16.1 0.0 0.0058 16.0 0.0 1.4 1 1 0 1 1 1 1 Putative esterase Esterase_phd PF10503.4 KEG10562.1 - 0.015 14.5 0.2 0.03 13.5 0.1 1.5 1 1 0 1 1 1 0 Esterase PHB depolymerase Ribosomal_L10 PF00466.15 KEG10563.1 - 6.7e-19 67.6 0.0 9.2e-19 67.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 VPS9 PF02204.13 KEG10564.1 - 4.7e-33 113.3 0.0 8.2e-33 112.5 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain HALZ PF02183.13 KEG10565.1 - 6.1e-05 22.6 1.7 0.00037 20.1 0.7 2.3 2 0 0 2 2 2 1 Homeobox associated leucine zipper DUF904 PF06005.7 KEG10565.1 - 0.00083 19.6 10.8 0.069 13.4 7.5 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF904) TMF_DNA_bd PF12329.3 KEG10565.1 - 0.013 15.2 9.5 0.071 12.9 2.6 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding FlaC_arch PF05377.6 KEG10565.1 - 0.04 13.8 2.2 3.8 7.4 0.2 2.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Desmo_N PF06771.6 KEG10565.1 - 0.046 13.6 0.3 5.2 7.0 0.0 2.3 1 1 0 2 2 2 0 Viral Desmoplakin N-terminus DUF3627 PF12299.3 KEG10565.1 - 0.055 13.5 0.2 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3627) BRE1 PF08647.6 KEG10565.1 - 0.066 13.1 6.9 0.15 12.0 4.8 1.7 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase Transposase_22 PF02994.9 KEG10565.1 - 0.12 10.7 5.1 0.13 10.7 0.1 2.0 1 1 0 2 2 2 0 L1 transposable element DUF3851 PF12962.2 KEG10565.1 - 0.14 12.1 0.5 0.16 11.9 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3851) DUF2675 PF11247.3 KEG10565.1 - 0.14 12.2 0.2 0.18 11.8 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2675) bZIP_1 PF00170.16 KEG10565.1 - 0.15 12.0 12.7 0.2 11.6 5.4 2.9 1 1 2 3 3 3 0 bZIP transcription factor Snf7 PF03357.16 KEG10565.1 - 0.16 11.3 8.6 0.43 9.9 0.5 2.1 1 1 1 2 2 2 0 Snf7 APG6 PF04111.7 KEG10565.1 - 0.22 10.5 11.1 0.23 10.4 7.7 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DDE_Tnp_1_6 PF13751.1 KEG10565.1 - 0.29 11.1 0.1 0.29 11.1 0.1 2.0 1 1 1 2 2 2 0 Transposase DDE domain SlyX PF04102.7 KEG10565.1 - 0.3 11.4 11.6 60 4.1 8.0 2.6 1 1 0 1 1 1 0 SlyX DUF972 PF06156.8 KEG10565.1 - 0.36 11.2 8.7 0.61 10.4 2.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Seryl_tRNA_N PF02403.17 KEG10565.1 - 0.52 10.3 6.3 9.8 6.2 4.4 2.2 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4140 PF13600.1 KEG10565.1 - 0.55 10.7 11.4 0.37 11.2 2.0 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) GAS PF13851.1 KEG10565.1 - 0.6 9.2 10.8 0.71 9.0 7.5 1.0 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Phage_GP20 PF06810.6 KEG10565.1 - 0.6 9.5 7.4 0.74 9.2 1.4 2.0 1 1 1 2 2 2 0 Phage minor structural protein GP20 Metal_resist PF13801.1 KEG10565.1 - 0.71 9.8 11.3 1.3 8.9 7.8 1.6 1 1 0 1 1 1 0 Heavy-metal resistance DUF3450 PF11932.3 KEG10565.1 - 0.87 8.7 10.1 0.97 8.6 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Mod_r PF07200.8 KEG10565.1 - 1 9.3 9.2 4.3 7.2 2.9 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DivIC PF04977.10 KEG10565.1 - 1 8.8 11.9 0.45 10.0 3.3 2.8 1 1 1 2 2 2 0 Septum formation initiator CENP-Q PF13094.1 KEG10565.1 - 1 9.3 15.1 1.9 8.4 7.8 2.0 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit XhlA PF10779.4 KEG10565.1 - 1.2 9.1 11.0 1.9 8.4 0.4 2.2 2 0 0 2 2 2 0 Haemolysin XhlA TBPIP PF07106.8 KEG10565.1 - 1.2 8.6 8.0 2.5 7.6 3.8 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) LTXXQ PF07813.7 KEG10565.1 - 1.2 9.6 12.7 31 5.0 8.8 2.0 1 1 0 1 1 1 0 LTXXQ motif family protein TPR_MLP1_2 PF07926.7 KEG10565.1 - 1.3 8.7 11.1 2.6 7.7 7.7 1.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Kinetocho_Slk19 PF12709.2 KEG10565.1 - 1.3 9.1 6.7 5.1 7.2 0.9 2.7 1 1 2 3 3 3 0 Central kinetochore-associated Spc7 PF08317.6 KEG10565.1 - 1.5 7.3 10.0 2 7.0 7.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein CASP_C PF08172.7 KEG10565.1 - 1.5 7.7 9.4 4.5 6.2 2.8 2.0 1 1 1 2 2 2 0 CASP C terminal ADIP PF11559.3 KEG10565.1 - 1.6 8.6 12.9 3 7.7 9.0 1.4 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF2968 PF11180.3 KEG10565.1 - 2.1 7.6 15.9 2.8 7.2 11.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF1843 PF08898.5 KEG10565.1 - 3.7 7.6 8.9 1.9 8.6 3.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1843) FUSC PF04632.7 KEG10565.1 - 3.9 5.7 5.9 4.1 5.7 4.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF342 PF03961.8 KEG10565.1 - 4.5 5.5 6.0 5.1 5.3 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4407 PF14362.1 KEG10565.1 - 5.6 5.8 7.9 6.8 5.5 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Bap31 PF05529.7 KEG10565.1 - 5.8 6.3 6.8 33 3.8 4.7 1.9 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like Atg14 PF10186.4 KEG10565.1 - 6.3 5.6 12.0 8.2 5.2 8.3 1.3 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Abhydrolase_6 PF12697.2 KEG10567.1 - 5.4e-17 62.4 3.1 5e-16 59.2 2.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family WD40 PF00400.27 KEG10568.1 - 8.2e-16 57.2 0.3 0.0055 16.5 0.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat Nop14 PF04147.7 KEG10568.1 - 6.3 4.5 39.6 9.2 4.0 27.4 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4551 PF15087.1 KEG10568.1 - 9.9 4.3 9.4 15 3.7 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Mito_carr PF00153.22 KEG10570.1 - 5.2e-09 35.7 2.7 8.8e-05 22.1 0.0 3.2 3 0 0 3 3 3 2 Mitochondrial carrier protein Arf PF00025.16 KEG10572.1 - 6.2e-64 214.4 0.0 7e-64 214.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KEG10572.1 - 3.8e-14 52.1 0.7 1.5e-08 33.7 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KEG10572.1 - 4.7e-10 39.0 0.0 5.6e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 KEG10572.1 - 9.1e-10 38.1 0.0 1.1e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KEG10572.1 - 2.9e-08 33.1 0.0 3.9e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KEG10572.1 - 9.9e-08 32.5 0.0 1.3e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KEG10572.1 - 5e-06 26.4 0.0 7.1e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KEG10572.1 - 6.9e-06 25.6 0.0 5.3e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain cobW PF02492.14 KEG10572.1 - 0.1 12.0 0.0 0.58 9.5 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain LMBR1 PF04791.11 KEG10573.1 - 1.1e-28 100.0 36.7 5.8e-15 54.8 8.9 2.1 1 1 1 2 2 2 2 LMBR1-like membrane protein Bap31 PF05529.7 KEG10573.1 - 9.8 5.5 9.7 3.6 7.0 3.7 2.5 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Clat_adaptor_s PF01217.15 KEG10574.1 - 2.2e-10 40.4 0.0 3.4e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AP-5_subunit_s1 PF15001.1 KEG10574.1 - 0.0036 17.2 0.1 0.0045 16.9 0.1 1.2 1 0 0 1 1 1 1 AP-5 complex subunit sigma-1 DUF4510 PF14971.1 KEG10574.1 - 0.13 12.4 0.1 0.45 10.6 0.1 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4510) UCR_14kD PF02271.11 KEG10575.1 - 3.6e-09 36.3 0.0 7.5e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit TrkH PF02386.11 KEG10577.1 - 2.8e-17 62.3 30.7 3.5e-10 39.0 15.2 4.1 2 1 0 2 2 2 2 Cation transport protein Band_7 PF01145.20 KEG10578.1 - 2.5e-25 89.3 1.1 3.8e-25 88.8 0.7 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Transket_pyr PF02779.19 KEG10581.1 - 8.3e-44 149.1 0.0 1.1e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KEG10581.1 - 7.9e-36 122.7 0.0 3.2e-35 120.7 0.0 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain Shal-type PF11601.3 KEG10581.1 - 0.1 12.1 0.6 0.21 11.1 0.4 1.5 1 0 0 1 1 1 0 Shal-type voltage-gated potassium channels Pkinase PF00069.20 KEG10583.1 - 7.9e-65 218.5 0.0 1.1e-64 218.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG10583.1 - 2.2e-31 108.9 0.1 3.5e-31 108.2 0.1 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KEG10583.1 - 2.8e-06 26.5 0.4 4.8e-06 25.7 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KEG10583.1 - 1.8e-05 23.8 0.1 4.9e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 KEG10583.1 - 0.021 14.1 0.3 0.041 13.2 0.2 1.4 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 KEG10583.1 - 0.029 14.1 0.5 1.2 8.8 0.2 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.20 KEG10585.1 - 1.1e-53 182.0 0.0 8.2e-53 179.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG10585.1 - 2.3e-30 105.5 0.0 8e-30 103.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KEG10585.1 - 1.2e-13 51.0 0.3 2.5e-12 46.7 0.2 2.5 1 1 0 1 1 1 1 FHA domain Kinase-like PF14531.1 KEG10585.1 - 1.5e-10 40.5 0.0 1.4e-07 30.7 0.0 2.6 2 1 0 2 2 2 2 Kinase-like RIO1 PF01163.17 KEG10585.1 - 0.072 12.4 0.0 0.17 11.2 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Aa_trans PF01490.13 KEG10586.1 - 2e-41 141.8 12.2 2.5e-41 141.4 8.4 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KEG10586.1 - 4.7e-07 28.9 14.2 9e-07 28.0 9.8 1.4 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family F-box-like PF12937.2 KEG10587.1 - 0.00014 21.4 0.1 0.00041 20.0 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KEG10587.1 - 0.0083 15.7 0.0 0.024 14.3 0.0 1.8 1 0 0 1 1 1 1 F-box domain DUF1738 PF08401.6 KEG10589.1 - 0.00022 20.9 0.0 0.0017 18.1 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1738) TTL PF03133.10 KEG10590.1 - 9.3e-46 156.0 0.0 1.4e-44 152.2 0.0 2.0 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 KEG10590.1 - 0.015 14.0 0.0 0.029 13.1 0.0 1.4 1 0 0 1 1 1 0 YheC/D like ATP-grasp PQQ_2 PF13360.1 KEG10592.1 - 0.00046 19.7 0.4 0.095 12.1 0.1 3.4 3 1 1 4 4 4 1 PQQ-like domain FG-GAP PF01839.18 KEG10592.1 - 0.0028 17.3 1.8 0.008 15.8 0.2 2.5 2 0 0 2 2 2 1 FG-GAP repeat VCBS PF13517.1 KEG10592.1 - 0.009 16.3 0.1 0.17 12.2 0.0 2.9 2 0 0 2 2 2 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella BBS2_C PF14782.1 KEG10592.1 - 0.065 11.7 0.0 0.099 11.1 0.0 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal UCH PF00443.24 KEG10593.1 - 3.9e-56 190.1 1.5 8.6e-56 188.9 0.3 2.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEG10593.1 - 1.6e-15 57.2 1.3 2.8e-08 33.5 0.0 2.6 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase CDC45 PF02724.9 KEG10593.1 - 0.0025 15.9 5.4 0.0048 15.0 3.7 1.3 1 0 0 1 1 1 1 CDC45-like protein Med4 PF10018.4 KEG10593.1 - 0.0035 16.7 8.1 0.0064 15.9 5.1 1.9 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 Daxx PF03344.10 KEG10593.1 - 0.42 9.0 14.1 0.71 8.2 9.8 1.2 1 0 0 1 1 1 0 Daxx Family Spore_coat_CotO PF14153.1 KEG10593.1 - 1.2 8.5 16.4 2.4 7.5 11.4 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Ycf1 PF05758.7 KEG10593.1 - 2 6.0 9.3 0.11 10.1 2.8 1.5 2 0 0 2 2 2 0 Ycf1 TRAP_alpha PF03896.11 KEG10593.1 - 3.5 6.5 9.2 7.4 5.4 6.4 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DDHD PF02862.12 KEG10593.1 - 5.2 6.8 8.5 11 5.7 5.9 1.4 1 0 0 1 1 1 0 DDHD domain Reo_sigmaC PF04582.7 KEG10594.1 - 0.02 14.0 0.7 0.02 14.0 0.5 2.0 2 1 0 2 2 2 0 Reovirus sigma C capsid protein Sec20 PF03908.8 KEG10594.1 - 3 7.5 13.6 1.7 8.4 1.9 4.0 3 1 0 3 3 3 0 Sec20 DUF1664 PF07889.7 KEG10594.1 - 9.3 6.0 17.6 2.2 8.1 4.5 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) SNAP PF14938.1 KEG10595.1 - 1.6e-55 188.2 17.2 1.8e-55 188.0 11.9 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 KEG10595.1 - 9.2e-09 35.1 7.0 2.1e-05 24.3 0.8 3.1 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEG10595.1 - 2.2e-07 30.8 5.8 0.027 15.0 0.2 4.7 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEG10595.1 - 4.3e-07 29.2 11.1 0.066 13.0 1.0 5.8 4 2 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEG10595.1 - 3e-06 27.4 5.9 0.032 14.5 0.5 2.9 1 1 0 2 2 2 2 Tetratricopeptide repeat Foie-gras_1 PF11817.3 KEG10595.1 - 0.0002 20.9 5.2 0.00054 19.5 3.6 1.7 1 1 0 1 1 1 1 Foie gras liver health family 1 TPR_6 PF13174.1 KEG10595.1 - 0.00066 19.9 12.6 0.2 12.1 0.0 5.8 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 KEG10595.1 - 0.005 16.4 12.2 0.094 12.3 1.1 4.1 4 1 0 4 4 4 1 TPR repeat PPR PF01535.15 KEG10595.1 - 0.0059 16.4 0.1 8.6 6.5 0.0 3.4 2 0 0 2 2 2 0 PPR repeat RPN7 PF10602.4 KEG10595.1 - 0.02 14.3 9.2 0.12 11.7 0.2 3.6 2 1 2 4 4 4 0 26S proteasome subunit RPN7 DUF2937 PF11157.3 KEG10595.1 - 0.045 13.0 1.5 0.21 10.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) TPR_2 PF07719.12 KEG10595.1 - 0.054 13.4 18.7 2.4 8.3 0.1 6.4 5 2 2 7 7 7 0 Tetratricopeptide repeat Apc3 PF12895.2 KEG10595.1 - 0.072 13.2 5.6 2.8 8.1 2.6 3.1 1 1 3 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.4 KEG10595.1 - 0.087 12.0 2.3 9.7 5.5 0.2 3.7 3 0 0 3 3 3 0 SHNi-TPR Phage_Gp14 PF10666.4 KEG10595.1 - 0.22 11.3 3.1 0.92 9.3 0.4 2.6 2 1 0 2 2 2 0 Phage protein Gp14 Sel1 PF08238.7 KEG10595.1 - 1.7 9.3 6.1 2.9 8.6 0.1 3.5 3 0 0 3 3 3 0 Sel1 repeat TPR_1 PF00515.23 KEG10595.1 - 3.2 7.5 10.7 19 5.0 0.6 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat Occludin_ELL PF07303.8 KEG10595.1 - 4.5 8.0 6.5 8.3 7.2 0.1 2.9 2 1 1 3 3 3 0 Occludin homology domain Ins145_P3_rec PF08709.6 KEG10597.1 - 0.00018 20.5 0.0 0.01 14.9 0.0 2.5 2 1 0 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor EF-hand_1 PF00036.27 KEG10597.1 - 0.005 16.0 1.1 0.029 13.6 0.4 2.3 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KEG10597.1 - 0.0071 15.9 0.0 0.033 13.7 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 KEG10597.1 - 0.02 15.0 0.1 0.21 11.7 0.1 2.4 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.1 KEG10597.1 - 0.022 14.6 0.4 0.27 11.2 0.1 2.6 3 0 0 3 3 3 0 EF-hand domain Pro_isomerase PF00160.16 KEG10598.1 - 9e-35 120.1 0.0 1e-34 120.0 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ArfGap PF01412.13 KEG10601.1 - 3e-24 85.0 0.0 5e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf CDC27 PF09507.5 KEG10601.1 - 5.5 6.0 12.7 9.3 5.3 8.8 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 His_Phos_2 PF00328.17 KEG10602.1 - 3.7e-06 26.5 0.0 7e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) TBCC PF07986.7 KEG10603.1 - 3.7e-27 94.1 1.9 5.9e-27 93.4 1.3 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.6 KEG10603.1 - 0.00073 18.9 0.2 0.0012 18.1 0.1 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal cobW PF02492.14 KEG10604.1 - 7e-44 149.3 0.1 9e-44 149.0 0.1 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 KEG10604.1 - 0.003 17.2 0.1 0.0098 15.6 0.1 1.9 1 1 0 1 1 1 1 Part of AAA domain CobW_C PF07683.9 KEG10604.1 - 0.0072 16.0 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain ATP_bind_1 PF03029.12 KEG10604.1 - 0.009 15.5 0.1 0.019 14.5 0.1 1.4 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.1 KEG10604.1 - 0.013 15.3 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KEG10604.1 - 0.038 14.2 0.2 0.12 12.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KEG10604.1 - 0.038 13.5 0.0 0.082 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 KEG10604.1 - 0.041 14.0 0.0 0.084 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KEG10604.1 - 0.086 12.7 0.0 0.62 9.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 KEG10604.1 - 0.11 12.2 0.1 0.22 11.2 0.1 1.6 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 KEG10604.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 NTPase zf-CCHC PF00098.18 KEG10606.1 - 2.6e-27 93.4 55.7 0.00071 19.3 1.0 9.9 9 0 0 9 9 9 9 Zinc knuckle NYN PF01936.13 KEG10606.1 - 6e-05 23.3 0.0 0.0003 21.1 0.0 1.9 1 1 0 1 1 1 1 NYN domain zf-CCHC_2 PF13696.1 KEG10606.1 - 0.00038 19.8 0.7 0.00038 19.8 0.5 8.4 4 2 4 8 8 8 5 Zinc knuckle zf-CCHC_4 PF14392.1 KEG10606.1 - 0.0038 16.8 63.0 0.034 13.8 2.2 9.3 9 0 0 9 9 9 6 Zinc knuckle Topoisom_bac PF01131.15 KEG10607.1 - 2.8e-98 329.4 0.0 3.6e-98 329.0 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 KEG10607.1 - 5.3e-10 39.1 0.0 1.1e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Toprim domain zf-GRF PF06839.7 KEG10607.1 - 7.9e-08 32.1 0.8 7.9e-08 32.1 0.6 2.3 2 0 0 2 2 2 1 GRF zinc finger zf-C4_Topoisom PF01396.14 KEG10607.1 - 6.2e-05 22.4 0.1 6.2e-05 22.4 0.1 3.3 3 0 0 3 3 3 1 Topoisomerase DNA binding C4 zinc finger Cullin_Nedd8 PF10557.4 KEG10607.1 - 0.078 12.8 0.0 15 5.5 0.0 2.6 2 0 0 2 2 2 0 Cullin protein neddylation domain RecR PF02132.10 KEG10607.1 - 4.3 6.8 9.3 0.16 11.4 1.0 2.9 3 0 0 3 3 3 0 RecR protein TMF_TATA_bd PF12325.3 KEG10609.1 - 0.0089 15.7 2.8 0.0089 15.7 2.0 6.2 4 1 2 6 6 6 4 TATA element modulatory factor 1 TATA binding Coleoptericin PF06286.6 KEG10610.1 - 0.0065 16.3 0.0 2.6 7.9 0.0 2.7 2 0 0 2 2 2 2 Coleoptericin KIAA1430 PF13879.1 KEG10610.1 - 0.012 16.0 2.8 0.015 15.7 0.4 2.2 1 1 1 2 2 2 0 KIAA1430 homologue 5-FTHF_cyc-lig PF01812.15 KEG10611.1 - 5.1e-20 72.0 0.0 2.6e-17 63.1 0.0 2.2 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Met_gamma_lyase PF06838.6 KEG10611.1 - 0.15 10.3 0.0 0.21 9.8 0.0 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase HIT PF01230.18 KEG10612.1 - 1e-11 45.1 0.3 1.9e-11 44.3 0.2 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KEG10612.1 - 0.0014 18.8 0.4 0.0053 16.9 0.3 1.9 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HAD_2 PF13419.1 KEG10613.1 - 0.11 12.6 0.0 0.81 9.8 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Methyltransf_23 PF13489.1 KEG10614.1 - 0.0058 16.3 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain LRR_4 PF12799.2 KEG10615.1 - 8.8e-18 63.5 3.0 0.0044 16.6 0.0 8.3 6 3 1 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG10615.1 - 2e-06 27.4 11.7 0.19 11.5 0.0 5.9 4 2 1 6 6 6 3 Leucine rich repeat LRR_7 PF13504.1 KEG10615.1 - 0.00021 20.9 18.7 15 6.3 0.0 9.9 11 0 0 11 11 11 1 Leucine rich repeat LRR_1 PF00560.28 KEG10615.1 - 1 9.6 13.9 1.1e+02 3.4 0.1 7.9 9 2 1 10 10 10 0 Leucine Rich Repeat LRR_6 PF13516.1 KEG10615.1 - 2.1 8.6 13.4 83 3.7 0.0 7.9 10 1 0 10 10 10 0 Leucine Rich repeat RRM_5 PF13893.1 KEG10616.1 - 0.0098 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEG10616.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cpn60_TCP1 PF00118.19 KEG10617.1 - 4.2e-137 457.6 5.8 4.8e-137 457.5 4.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Tetraspannin PF00335.15 KEG10618.1 - 5.1e-21 74.9 10.6 7e-21 74.5 7.4 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF1625 PF07787.7 KEG10618.1 - 0.013 14.7 0.7 0.013 14.7 0.5 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1625) TMEM169 PF15052.1 KEG10618.1 - 4.1 7.3 12.0 0.041 13.8 1.9 2.2 2 1 1 3 3 3 0 TMEM169 protein family Vma12 PF11712.3 KEG10618.1 - 6 6.5 8.2 17 5.0 5.7 1.7 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Glucosamine_iso PF01182.15 KEG10619.1 - 6.2e-22 78.2 0.0 8.2e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase FAD_binding_8 PF08022.7 KEG10619.1 - 0.03 14.1 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 FAD-binding domain FabA PF07977.8 KEG10619.1 - 0.034 13.6 0.0 0.072 12.5 0.0 1.5 1 0 0 1 1 1 0 FabA-like domain Pkinase PF00069.20 KEG10620.1 - 1.6e-75 253.5 0.0 2.2e-75 253.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG10620.1 - 6.4e-40 136.8 0.0 2.2e-39 135.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG10620.1 - 8.5e-05 21.6 0.0 0.00026 20.0 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KEG10620.1 - 0.0098 15.6 1.0 0.38 10.4 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KEG10620.1 - 0.071 11.9 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF3633 PF12315.3 KEG10621.1 - 0.24 10.6 0.6 0.49 9.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3633) Miro PF08477.8 KEG10622.1 - 3.1e-06 27.6 0.0 4.4e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein FtsK_SpoIIIE PF01580.13 KEG10622.1 - 0.00017 21.1 0.1 0.00058 19.3 0.0 1.9 2 0 0 2 2 2 1 FtsK/SpoIIIE family GTP_EFTU PF00009.22 KEG10622.1 - 0.00036 20.0 0.0 0.71 9.2 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KEG10622.1 - 0.0034 17.5 0.0 0.0094 16.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEG10622.1 - 0.0039 16.9 0.2 0.011 15.5 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain Arf PF00025.16 KEG10622.1 - 0.0039 16.4 0.1 0.14 11.4 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_16 PF13191.1 KEG10622.1 - 0.0074 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain MCM PF00493.18 KEG10622.1 - 0.0087 14.9 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MMR_HSR1 PF01926.18 KEG10622.1 - 0.0089 15.9 0.2 0.017 15.0 0.2 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_5 PF07728.9 KEG10622.1 - 0.011 15.4 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KEG10622.1 - 0.015 15.2 0.6 0.24 11.2 0.1 2.4 1 1 1 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 KEG10622.1 - 0.015 13.9 0.0 0.027 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.7 KEG10622.1 - 0.024 14.2 0.1 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 KEG10622.1 - 0.025 14.7 0.0 0.13 12.4 0.0 2.1 2 0 0 2 2 2 0 RNA helicase UvrD-helicase PF00580.16 KEG10622.1 - 0.028 13.7 0.2 0.045 13.0 0.1 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_25 PF13481.1 KEG10622.1 - 0.031 13.7 0.4 0.11 11.9 0.2 1.9 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 KEG10622.1 - 0.033 13.1 0.0 0.05 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.1 KEG10622.1 - 0.038 13.9 0.0 0.083 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KEG10622.1 - 0.045 13.1 0.3 0.14 11.6 0.1 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.7 KEG10622.1 - 0.047 12.7 0.1 0.089 11.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin FeoB_N PF02421.13 KEG10622.1 - 0.07 12.4 0.1 0.17 11.1 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_24 PF13479.1 KEG10622.1 - 0.073 12.6 0.0 0.37 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 KEG10622.1 - 0.085 11.7 0.3 0.24 10.2 0.1 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein Mg_chelatase PF01078.16 KEG10622.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 KEG10622.1 - 0.11 12.0 1.0 0.41 10.1 0.0 2.2 3 0 0 3 3 3 0 AAA domain DUF2970 PF11174.3 KEG10624.1 - 0.035 13.6 0.0 0.035 13.6 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2970) Baculo_11_kDa PF06143.6 KEG10624.1 - 0.13 11.6 0.5 0.63 9.4 0.0 2.4 2 0 0 2 2 2 0 Baculovirus 11 kDa family Dopey_N PF04118.9 KEG10626.1 - 2.4e-30 105.3 0.0 1.4e-29 102.8 0.0 2.1 1 1 0 1 1 1 1 Dopey, N-terminal Abhydrolase_6 PF12697.2 KEG10627.1 - 4.8e-06 26.6 0.0 2.1e-05 24.5 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEG10627.1 - 0.0002 20.9 0.0 0.00036 20.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold zf-MYND PF01753.13 KEG10628.1 - 1.5e-05 24.7 7.5 4.5e-05 23.2 5.2 1.9 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KEG10628.1 - 0.02 14.7 3.6 0.053 13.3 2.5 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 RhoGAP PF00620.22 KEG10628.1 - 0.022 14.3 0.1 0.05 13.2 0.0 1.5 1 0 0 1 1 1 0 RhoGAP domain TruD PF01142.13 KEG10629.1 - 4.7e-40 137.4 0.0 2.6e-32 111.9 0.0 3.2 2 1 1 3 3 3 3 tRNA pseudouridine synthase D (TruD) EMP70 PF02990.11 KEG10630.1 - 1.3e-130 436.2 0.3 1.6e-130 436.0 0.2 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 ATP-synt_ab PF00006.20 KEG10631.1 - 3.2e-109 363.4 0.0 5.1e-109 362.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KEG10631.1 - 5e-24 84.9 0.2 8.1e-24 84.2 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KEG10631.1 - 2.3e-20 72.5 8.6 2.4e-15 56.4 0.9 3.0 3 0 0 3 3 3 2 ATP synthase alpha/beta family, beta-barrel domain AAA_16 PF13191.1 KEG10631.1 - 0.082 12.8 0.0 0.4 10.6 0.0 1.9 1 1 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 KEG10631.1 - 0.093 12.6 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ribosomal_L13 PF00572.13 KEG10632.1 - 1.6e-28 99.2 0.0 2.2e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 Ins_P5_2-kin PF06090.7 KEG10634.1 - 2.7e-16 59.5 0.0 1e-15 57.5 0.0 1.8 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DUF501 PF04417.7 KEG10636.1 - 6.8e-33 113.4 0.2 1.1e-32 112.7 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF501) Aminotran_1_2 PF00155.16 KEG10638.1 - 1e-42 146.4 0.0 1.3e-42 146.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II WD40 PF00400.27 KEG10642.1 - 2.2e-27 93.8 2.7 8.5e-07 28.6 0.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Methyltransf_18 PF12847.2 KEG10642.1 - 0.061 13.9 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CotH PF08757.6 KEG10643.1 - 1.7e-07 30.7 0.0 2.5e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 CotH protein Macoilin PF09726.4 KEG10644.1 - 1.1 7.4 5.4 1.9 6.6 3.8 1.3 1 0 0 1 1 1 0 Transmembrane protein MerE PF05052.7 KEG10645.1 - 1.4 8.9 7.5 0.26 11.2 0.1 2.6 3 0 0 3 3 3 0 MerE protein MORN PF02493.15 KEG10647.1 - 3.6e-08 32.6 8.0 0.0026 17.3 0.4 4.0 4 0 0 4 4 4 2 MORN repeat Atg8 PF02991.11 KEG10648.1 - 8.3e-28 96.4 0.0 9.4e-27 93.0 0.0 2.0 1 1 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 KEG10648.1 - 1.8e-06 28.0 0.0 2.5e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 CHAP PF05257.11 KEG10649.1 - 3.2e-20 72.0 0.1 5e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 CHAP domain Amidase_6 PF12671.2 KEG10649.1 - 0.045 13.8 0.0 0.11 12.5 0.0 1.7 1 1 0 1 1 1 0 Putative amidase domain CHAP PF05257.11 KEG10650.1 - 8.9e-06 25.3 1.2 0.00019 21.1 0.8 2.6 1 1 0 1 1 1 1 CHAP domain Amidase_6 PF12671.2 KEG10650.1 - 0.056 13.4 0.6 0.29 11.1 0.0 2.0 1 1 1 2 2 2 0 Putative amidase domain Glyco_transf_10 PF00852.14 KEG10654.1 - 2e-26 92.4 0.7 8.1e-22 77.2 0.1 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 10 (fucosyltransferase) Plasmodium_Vir PF05795.6 KEG10655.1 - 1 8.4 8.3 12 5.0 5.8 2.1 1 1 0 1 1 1 0 Plasmodium vivax Vir protein ADIP PF11559.3 KEG10658.1 - 0.053 13.4 1.8 0.12 12.3 1.3 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Ras PF00071.17 KEG10659.1 - 1.9e-25 89.1 0.0 4e-21 75.0 0.0 2.2 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KEG10659.1 - 6.7e-12 45.9 0.1 2.3e-11 44.1 0.1 1.9 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEG10659.1 - 1.2e-07 31.1 0.0 1.4e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KEG10659.1 - 7.1e-07 28.8 0.0 2.8e-06 26.8 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KEG10659.1 - 6.3e-05 22.2 0.0 0.00011 21.4 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KEG10659.1 - 0.00012 22.0 0.0 0.00023 21.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF3456 PF11938.3 KEG10661.1 - 4.4e-06 26.7 0.0 0.0022 17.9 0.0 2.1 1 1 1 2 2 2 2 TLR4 regulator and MIR-interacting MSAP RRM_1 PF00076.17 KEG10662.1 - 5e-06 26.0 0.0 1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG10662.1 - 0.0045 16.9 0.0 0.0099 15.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) IBR PF01485.16 KEG10663.1 - 0.028 14.2 0.7 0.028 14.2 0.5 1.7 2 0 0 2 2 2 0 IBR domain 7tm_2 PF00002.19 KEG10663.1 - 0.076 12.0 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) GHMP_kinases_N PF00288.21 KEG10664.1 - 8.4e-07 28.9 3.6 2.3e-06 27.5 2.5 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain X PF00739.14 KEG10664.1 - 0.11 12.4 0.5 0.22 11.4 0.3 1.5 1 0 0 1 1 1 0 Trans-activation protein X RRM_5 PF13893.1 KEG10665.1 - 1.9e-06 27.5 0.0 0.00043 20.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG10665.1 - 5.1e-06 26.3 0.0 0.013 15.4 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEG10665.1 - 6.6e-06 25.6 0.0 0.0028 17.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.11 KEG10666.1 - 1e-26 93.5 42.5 1e-26 93.5 29.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 KEG10666.1 - 1.6e-10 39.7 31.3 6.5e-06 24.4 0.7 4.6 2 2 3 5 5 5 3 Organic Anion Transporter Polypeptide (OATP) family Cytochrom_C552 PF02335.10 KEG10667.1 - 0.011 14.5 0.8 0.15 10.7 0.2 2.1 2 0 0 2 2 2 0 Cytochrome c552 Antimicrobial14 PF08109.6 KEG10667.1 - 0.1 12.4 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Lactocin 705 family Spo0M PF07070.6 KEG10667.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 SpoOM protein SurA_N PF09312.6 KEG10668.1 - 0.061 13.1 0.1 0.084 12.7 0.1 1.2 1 0 0 1 1 1 0 SurA N-terminal domain zf-C2HC_2 PF13913.1 KEG10669.1 - 9.5e-41 136.6 56.3 3.6e-10 39.2 0.6 8.0 9 0 0 9 9 9 6 zinc-finger of a C2HC-type DZR PF12773.2 KEG10669.1 - 3.8e-20 71.4 54.2 3.3e-09 36.4 10.1 7.9 5 3 2 7 7 7 4 Double zinc ribbon zinc_ribbon_2 PF13240.1 KEG10669.1 - 1.9e-14 52.6 55.1 0.0008 18.8 3.9 8.9 8 0 0 8 8 8 6 zinc-ribbon domain zf-ribbon_3 PF13248.1 KEG10669.1 - 7.1e-14 50.5 59.5 2e-05 23.6 0.9 8.9 9 0 0 9 9 9 6 zinc-ribbon domain NOB1_Zn_bind PF08772.6 KEG10669.1 - 0.0025 17.6 1.2 0.0025 17.6 0.9 7.5 7 1 1 8 8 8 3 Nin one binding (NOB1) Zn-ribbon like Rad50_zn_hook PF04423.9 KEG10669.1 - 0.06 12.8 7.2 20 4.7 0.0 5.0 5 0 0 5 5 5 0 Rad50 zinc hook motif Sgf11 PF08209.6 KEG10669.1 - 0.062 12.6 0.3 0.062 12.6 0.2 7.3 10 0 0 10 10 10 0 Sgf11 (transcriptional regulation protein) Evr1_Alr PF04777.8 KEG10669.1 - 0.41 10.5 10.3 6.5 6.7 0.0 5.5 5 0 0 5 5 5 0 Erv1 / Alr family zf-C2H2 PF00096.21 KEG10669.1 - 4.5 7.8 47.8 0.23 11.8 0.2 8.7 10 0 0 10 10 10 0 Zinc finger, C2H2 type zf-DHHC PF01529.15 KEG10669.1 - 9.5 5.5 15.8 1.1 8.5 0.6 4.3 3 1 1 4 4 4 0 DHHC palmitoyltransferase DGF-1_5 PF11038.3 KEG10670.1 - 9e-115 382.6 2.5 9e-115 382.6 1.7 2.3 2 0 0 2 2 2 1 Dispersed gene family protein 1 of Trypanosoma cruzi region 5 SHR3_chaperone PF08229.6 KEG10670.1 - 0.0015 17.5 0.0 0.0033 16.4 0.0 1.5 1 0 0 1 1 1 1 ER membrane protein SH3 Pkinase PF00069.20 KEG10672.1 - 3.7e-35 121.3 0.0 6.6e-35 120.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG10672.1 - 4.5e-28 98.0 0.0 6.8e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG10672.1 - 0.0038 16.2 0.0 0.0072 15.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEG10672.1 - 0.016 14.9 0.2 0.54 9.9 0.0 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KEG10672.1 - 0.24 10.1 0.0 0.33 9.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase ORC6 PF05460.8 KEG10673.1 - 0.036 13.1 5.4 0.045 12.8 3.8 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF3246 PF11596.3 KEG10673.1 - 0.047 12.9 0.9 0.051 12.8 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) DUF4611 PF15387.1 KEG10673.1 - 0.05 13.7 3.1 0.059 13.5 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF3451 PF11933.3 KEG10673.1 - 0.12 12.0 8.1 0.15 11.8 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3451) CKAP2_C PF15297.1 KEG10673.1 - 0.15 10.8 6.3 0.16 10.7 4.4 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Inhibitor_I71 PF12628.2 KEG10673.1 - 0.59 9.7 3.0 0.69 9.5 2.1 1.1 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor Rtf2 PF04641.7 KEG10673.1 - 0.62 9.2 12.3 0.71 9.0 8.5 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger U79_P34 PF03064.11 KEG10673.1 - 0.83 9.1 13.5 0.92 8.9 9.4 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Vfa1 PF08432.5 KEG10673.1 - 1.1 9.2 11.1 1.3 9.0 7.7 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 GTSE1_N PF15259.1 KEG10673.1 - 1.5 8.7 6.1 2.6 7.9 4.2 1.4 1 1 0 1 1 1 0 G-2 and S-phase expressed 1 NAM-associated PF14303.1 KEG10673.1 - 1.9 8.8 12.8 2.3 8.5 8.9 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain CDC45 PF02724.9 KEG10673.1 - 5.8 4.8 10.8 6.5 4.6 7.5 1.0 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.1 KEG10673.1 - 6.1 6.5 9.0 8.2 6.0 6.2 1.3 1 1 0 1 1 1 0 FAM176 family Cut8_N PF14482.1 KEG10673.1 - 6.2 6.9 15.9 0.73 9.8 6.5 2.3 1 1 1 2 2 2 0 Cut8 proteasome-binding domain Selenoprotein_S PF06936.6 KEG10673.1 - 6.6 6.2 9.7 7.4 6.0 6.7 1.0 1 0 0 1 1 1 0 Selenoprotein S (SelS) NnrU PF07298.6 KEG10675.1 - 0.0095 15.3 1.9 0.014 14.7 1.3 1.2 1 0 0 1 1 1 1 NnrU protein YjbE PF11106.3 KEG10675.1 - 1.2 9.1 7.3 2 8.4 5.1 1.3 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE Mucin PF01456.12 KEG10676.1 - 0.72 9.6 23.8 19 5.0 16.5 2.6 1 1 0 1 1 1 0 Mucin-like glycoprotein Spore_YhcN_YlaJ PF09580.5 KEG10676.1 - 2.6 8.1 5.9 1.1 9.3 2.3 1.6 1 1 1 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Glycophorin_A PF01102.13 KEG10676.1 - 3.4 7.4 6.4 15 5.3 0.2 2.1 1 1 1 2 2 2 0 Glycophorin A SNF2_N PF00176.18 KEG10677.1 - 1.2e-52 178.5 0.1 1.7e-52 178.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEG10677.1 - 7.9e-16 57.6 0.0 1.8e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEG10677.1 - 5e-07 29.3 0.0 8.3e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KEG10677.1 - 3.1e-05 23.8 0.0 0.00018 21.4 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Beta_helix PF13229.1 KEG10678.1 - 2.7e-06 27.2 0.0 5e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Right handed beta helix region NosD PF05048.8 KEG10678.1 - 0.00097 18.3 0.0 0.0016 17.6 0.0 1.2 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Enkurin PF13864.1 KEG10679.1 - 1e-23 83.3 6.5 1e-23 83.3 4.5 2.2 2 0 0 2 2 2 1 Calmodulin-binding Thioredoxin PF00085.15 KEG10680.1 - 1.6e-21 75.9 0.1 1.8e-21 75.7 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KEG10680.1 - 5.5e-05 23.3 0.1 0.00046 20.3 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KEG10680.1 - 0.0085 16.1 0.2 0.041 14.0 0.1 1.9 1 1 1 2 2 2 1 Thioredoxin-like VP9 PF09625.5 KEG10680.1 - 0.015 15.0 0.0 0.85 9.4 0.0 2.1 2 0 0 2 2 2 0 VP9 protein AhpC-TSA PF00578.16 KEG10680.1 - 0.028 14.1 0.1 0.046 13.4 0.1 1.4 1 1 0 1 1 1 0 AhpC/TSA family Phosducin PF02114.11 KEG10680.1 - 0.049 12.3 0.0 0.052 12.2 0.0 1.1 1 0 0 1 1 1 0 Phosducin Acetyltransf_1 PF00583.19 KEG10681.1 - 2e-16 59.7 0.0 6.4e-08 32.5 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEG10681.1 - 4.5e-14 52.3 0.0 1.2e-06 28.5 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KEG10681.1 - 3.5e-11 43.2 0.0 1.1e-06 28.7 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KEG10681.1 - 0.00015 21.5 0.0 0.0024 17.7 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KEG10681.1 - 0.0018 18.1 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 2 GCN5-related N-acetyl-transferase FR47 PF08445.5 KEG10681.1 - 0.0075 15.9 0.0 0.025 14.3 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_4 PF13420.1 KEG10681.1 - 0.018 14.9 0.0 0.5 10.2 0.0 2.5 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 KEG10681.1 - 0.048 13.6 0.0 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain PseudoU_synth_2 PF00849.17 KEG10682.1 - 1.4e-22 80.2 0.0 3.9e-22 78.8 0.0 1.7 2 0 0 2 2 2 1 RNA pseudouridylate synthase DUF412 PF04217.8 KEG10682.1 - 0.027 14.2 0.1 0.049 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF412 Cmc1 PF08583.5 KEG10683.1 - 4.4e-06 26.3 1.9 9.2e-06 25.3 1.3 1.6 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like HTH_27 PF13463.1 KEG10683.1 - 0.042 14.1 0.1 0.071 13.4 0.1 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain Bcr-Abl_Oligo PF09036.5 KEG10683.1 - 0.11 12.4 1.4 0.49 10.3 0.2 2.3 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain CHCH PF06747.8 KEG10683.1 - 0.16 11.9 1.2 15 5.6 0.0 2.4 2 0 0 2 2 2 0 CHCH domain UCR_hinge PF02320.11 KEG10683.1 - 0.35 10.8 4.8 1.9 8.5 1.7 2.3 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein PX PF00787.19 KEG10684.1 - 3.3e-14 52.6 0.0 1e-13 51.0 0.0 1.8 1 0 0 1 1 1 1 PX domain DHHA2 PF02833.9 KEG10685.1 - 7.2e-20 71.4 0.0 1.1e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 KEG10685.1 - 2.5e-10 40.1 0.0 3.6e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 DHH family WD40 PF00400.27 KEG10686.1 - 4e-30 102.5 12.9 0.00021 21.0 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat WWE PF02825.15 KEG10686.1 - 1.1e-07 31.1 0.1 2.6e-07 29.9 0.0 1.7 2 0 0 2 2 2 1 WWE domain Nup160 PF11715.3 KEG10686.1 - 0.096 10.8 0.4 0.18 9.9 0.0 1.5 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Prefoldin PF02996.12 KEG10689.1 - 2e-21 75.8 0.4 2.4e-21 75.6 0.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit Sec2p PF06428.6 KEG10689.1 - 0.0035 17.1 2.2 0.075 12.8 0.6 2.3 2 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p MscS_porin PF12795.2 KEG10689.1 - 0.013 14.7 1.1 0.018 14.3 0.2 1.5 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Prefoldin_2 PF01920.15 KEG10689.1 - 0.015 15.0 0.4 0.16 11.7 0.0 2.1 2 0 0 2 2 2 0 Prefoldin subunit End3 PF12761.2 KEG10689.1 - 0.065 12.8 0.7 0.14 11.7 0.5 1.8 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 KxDL PF10241.4 KEG10689.1 - 0.078 12.8 0.2 0.64 9.9 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein MMR_HSR1 PF01926.18 KEG10690.1 - 9e-16 57.8 0.0 1.1e-12 47.9 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 KEG10690.1 - 3.5e-07 29.6 0.1 0.00026 20.3 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF258 PF03193.11 KEG10690.1 - 0.00038 19.6 0.0 0.00092 18.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KEG10690.1 - 0.0005 19.5 0.1 0.91 8.9 0.0 2.7 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KEG10690.1 - 0.0015 18.3 1.0 0.015 15.1 0.1 2.7 1 1 1 2 2 2 1 Dynamin family FUSC_2 PF13515.1 KEG10691.1 - 1e-09 38.4 11.4 1e-09 38.4 7.9 3.2 3 1 0 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.3 KEG10691.1 - 0.0028 16.3 3.9 0.0028 16.3 2.7 2.3 2 0 0 2 2 2 1 Aluminium activated malate transporter Plasmodium_Vir PF05795.6 KEG10691.1 - 2.4 7.2 2.0 4.7 6.3 1.4 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Thioredoxin PF00085.15 KEG10692.1 - 0.00069 19.2 0.2 0.026 14.2 0.0 2.7 2 1 0 2 2 2 1 Thioredoxin DUF4278 PF14105.1 KEG10692.1 - 0.042 13.7 0.1 0.097 12.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4278) Metallophos PF00149.23 KEG10693.1 - 9.5e-34 116.5 0.9 1.3e-33 116.0 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase GF_recep_IV PF14843.1 KEG10694.1 - 0.0054 16.3 3.9 0.012 15.1 0.8 2.5 2 0 0 2 2 2 1 Growth factor receptor domain IV NARG2_C PF10505.4 KEG10694.1 - 0.042 13.0 0.1 0.15 11.1 0.0 1.8 1 1 1 2 2 2 0 NMDA receptor-regulated gene protein 2 C-terminus ScdA_N PF04405.9 KEG10694.1 - 0.043 13.1 0.8 5.9 6.3 0.0 2.7 1 1 1 2 2 2 0 Domain of Unknown function (DUF542) adh_short PF00106.20 KEG10695.1 - 1.2e-17 64.3 1.6 2.1e-17 63.5 1.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEG10695.1 - 3.6e-08 33.2 0.9 5.9e-08 32.5 0.6 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEG10695.1 - 8.7e-05 22.3 0.0 0.00014 21.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KEG10695.1 - 0.0038 16.7 0.0 0.012 15.0 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Lipase_3 PF01764.20 KEG10696.1 - 1.1e-08 34.8 0.1 5.8e-08 32.4 0.0 2.0 2 0 0 2 2 2 1 Lipase (class 3) Thioesterase PF00975.15 KEG10696.1 - 4.4e-05 23.8 2.5 0.00011 22.4 0.0 2.4 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.2 KEG10696.1 - 0.00079 19.3 1.4 0.00085 19.2 0.2 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KEG10696.1 - 0.00084 18.9 0.0 0.0021 17.7 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein YjeF_N PF03853.10 KEG10696.1 - 0.01 15.4 0.1 0.031 13.8 0.1 1.8 1 0 0 1 1 1 0 YjeF-related protein N-terminus Abhydrolase_1 PF00561.15 KEG10696.1 - 0.075 12.5 0.0 0.76 9.2 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold adh_short PF00106.20 KEG10697.1 - 3.8e-15 56.2 2.8 2.4e-09 37.3 0.0 2.5 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.5 KEG10697.1 - 0.00066 19.3 0.6 0.43 10.2 0.4 2.3 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 KEG10697.1 - 0.0032 17.2 0.0 0.009 15.8 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Pkinase PF00069.20 KEG10698.1 - 1.8e-60 204.2 0.0 2.4e-60 203.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG10698.1 - 4.5e-31 107.8 0.0 1.4e-30 106.2 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG10698.1 - 1e-11 44.3 0.0 7.7e-11 41.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KEG10698.1 - 3.2e-05 23.7 1.9 0.011 15.5 0.3 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 KEG10698.1 - 0.0038 16.5 0.0 0.01 15.1 0.0 1.6 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.9 KEG10698.1 - 0.0064 15.5 0.0 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KEG10698.1 - 0.23 10.2 0.0 0.34 9.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.15 KEG10698.1 - 0.27 10.7 0.0 0.49 9.9 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Cytochrom_C_2 PF01322.15 KEG10699.1 - 0.0017 18.9 3.4 0.0018 18.8 0.3 2.4 3 0 0 3 3 3 1 Cytochrome C' Haem_bd PF14376.1 KEG10699.1 - 0.0058 16.3 1.0 0.01 15.5 0.1 1.8 2 0 0 2 2 2 1 Haem-binding domain Reo_sigmaC PF04582.7 KEG10699.1 - 0.12 11.4 1.3 2.8 7.0 0.3 2.3 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Spc7 PF08317.6 KEG10699.1 - 0.21 10.2 14.5 0.098 11.2 7.4 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein IncA PF04156.9 KEG10699.1 - 7.6 6.0 36.8 1.9 8.0 13.3 3.3 1 1 2 3 3 3 0 IncA protein TMF_TATA_bd PF12325.3 KEG10699.1 - 9.9 5.9 26.1 0.51 10.0 3.8 3.3 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding PC-Esterase PF13839.1 KEG10700.1 - 2.4e-13 50.5 0.1 3.9e-13 49.8 0.1 1.3 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p PMR5N PF14416.1 KEG10700.1 - 0.015 15.3 3.2 0.066 13.2 1.3 2.8 2 1 0 2 2 2 0 PMR5 N terminal Domain Synaptobrevin PF00957.16 KEG10701.1 - 8.4e-15 54.1 0.3 1.5e-14 53.3 0.2 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 KEG10701.1 - 4.1e-11 42.2 0.0 6.5e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Vps5 PF09325.5 KEG10702.1 - 5.5e-25 87.9 9.9 7.7e-25 87.5 6.9 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 KEG10702.1 - 3.3e-18 65.5 0.0 7e-18 64.4 0.0 1.6 1 0 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.4 KEG10702.1 - 2.3e-07 30.3 5.6 2e-05 24.0 0.6 2.3 1 1 1 2 2 2 2 WASP-binding domain of Sorting nexin protein BAR PF03114.13 KEG10702.1 - 3.2e-07 30.1 8.8 5e-07 29.4 6.1 1.3 1 0 0 1 1 1 1 BAR domain Laminin_II PF06009.7 KEG10702.1 - 0.38 10.5 5.0 2.4 7.9 0.3 2.5 1 1 1 2 2 2 0 Laminin Domain II Syntaxin_2 PF14523.1 KEG10702.1 - 3.5 7.7 10.0 2.5 8.1 2.4 3.1 2 1 1 3 3 3 0 Syntaxin-like protein Peptidase_M8 PF01457.11 KEG10703.1 - 2.1e-97 326.6 0.0 2.7e-97 326.2 0.0 1.1 1 0 0 1 1 1 1 Leishmanolysin CATSPERD PF15020.1 KEG10703.1 - 0.41 8.6 1.0 0.6 8.0 0.7 1.1 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit delta FAM163 PF15069.1 KEG10704.1 - 0.018 15.6 0.2 0.092 13.3 0.2 2.2 1 1 0 1 1 1 0 FAM163 family DUF1628 PF07790.6 KEG10704.1 - 0.23 12.2 1.1 11 6.8 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1628) FAA_hydrolase PF01557.13 KEG10705.1 - 1e-41 142.7 0.1 1.3e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family HECT PF00632.20 KEG10706.1 - 4.1e-68 229.8 0.0 7.8e-68 228.9 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WWE PF02825.15 KEG10706.1 - 0.077 12.4 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 WWE domain RRP7 PF12923.2 KEG10707.1 - 0.0065 16.4 10.8 0.0065 16.4 7.5 3.3 2 2 1 3 3 3 1 Ribosomal RNA-processing protein 7 (RRP7) DUF3492 PF11997.3 KEG10707.1 - 0.06 12.8 0.2 0.06 12.8 0.2 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3492) RRM_1 PF00076.17 KEG10708.1 - 3.2e-18 65.1 0.0 4.1e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG10708.1 - 5e-14 52.0 0.0 6.5e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG10708.1 - 1e-10 41.2 0.0 1.8e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HA2 PF04408.18 KEG10709.1 - 3.5e-18 65.5 0.0 1.3e-17 63.6 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KEG10709.1 - 6.2e-14 51.7 0.0 1.5e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KEG10709.1 - 3.7e-11 42.7 0.1 8.9e-11 41.4 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEG10709.1 - 9.3e-09 34.9 0.2 3.2e-08 33.2 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KEG10709.1 - 8.9e-06 25.8 0.1 0.00039 20.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 KEG10709.1 - 0.00039 19.4 0.0 0.00098 18.0 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein RWD PF05773.17 KEG10709.1 - 0.0017 18.2 0.0 0.0057 16.5 0.0 1.9 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KEG10709.1 - 0.028 14.1 0.0 0.074 12.7 0.0 1.6 1 0 0 1 1 1 0 UEV domain Zeta_toxin PF06414.7 KEG10709.1 - 0.03 13.4 0.1 0.097 11.7 0.0 1.8 1 1 0 1 1 1 0 Zeta toxin AAA_11 PF13086.1 KEG10709.1 - 0.034 13.7 0.0 0.14 11.6 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_19 PF13245.1 KEG10709.1 - 0.045 13.5 0.1 0.14 11.9 0.1 1.9 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 KEG10709.1 - 0.069 12.8 0.3 12 5.4 0.0 3.0 3 0 0 3 3 2 0 NACHT domain KaiC PF06745.8 KEG10709.1 - 0.095 11.7 0.5 0.21 10.6 0.0 1.7 2 0 0 2 2 2 0 KaiC AAA_23 PF13476.1 KEG10709.1 - 0.11 12.8 0.0 0.35 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 KEG10709.1 - 0.11 12.3 0.0 8.2 6.2 0.0 2.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit zf-CCHC PF00098.18 KEG10709.1 - 0.29 11.1 8.3 0.13 12.2 2.5 2.5 2 0 0 2 2 2 0 Zinc knuckle RRM_1 PF00076.17 KEG10710.1 - 8.7e-19 66.9 0.0 1.2e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG10710.1 - 1.4e-14 53.7 0.0 1.9e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG10710.1 - 6.1e-08 32.3 0.1 1.1e-07 31.5 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HhH-GPD PF00730.20 KEG10711.1 - 4.6e-18 65.4 0.0 8.5e-18 64.6 0.0 1.4 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KEG10711.1 - 5.6e-07 28.9 0.0 1.2e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 KEG10711.1 - 0.00096 19.2 0.0 0.15 12.2 0.0 2.0 1 1 1 2 2 2 2 Helix-hairpin-helix domain DUF763 PF05559.6 KEG10711.1 - 0.084 11.8 0.0 0.3 9.9 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF763) PIG-L PF02585.12 KEG10712.1 - 2.1e-25 89.6 0.0 3.1e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF1656 PF07869.7 KEG10712.1 - 1 9.1 4.4 12 5.7 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) DUF3253 PF11625.3 KEG10713.1 - 0.011 15.6 0.1 0.011 15.6 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3253) Syntaxin-6_N PF09177.6 KEG10713.1 - 0.019 15.3 4.3 0.019 15.3 3.0 3.1 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Seadorna_VP6 PF07407.6 KEG10713.1 - 0.13 11.0 4.2 0.077 11.7 1.7 1.4 1 1 0 1 1 1 0 Seadornavirus VP6 protein PAP_central PF04928.12 KEG10713.1 - 0.13 11.0 2.8 0.063 12.0 0.3 1.6 2 0 0 2 2 2 0 Poly(A) polymerase central domain WXG100 PF06013.7 KEG10713.1 - 3 7.9 10.0 0.73 9.8 1.6 2.9 2 1 1 3 3 3 0 Proteins of 100 residues with WXG XPG_I_2 PF12813.2 KEG10713.1 - 8.4 5.7 11.6 0.036 13.5 1.0 2.0 2 1 0 2 2 2 0 XPG domain containing PEX11 PF05648.9 KEG10714.1 - 2.2e-13 50.0 2.3 2.2e-11 43.4 1.6 2.6 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Suf PF05843.9 KEG10715.1 - 0.0092 15.7 0.0 0.03 14.0 0.0 1.8 1 1 0 1 1 1 1 Suppressor of forked protein (Suf) NIP_1 PF08995.5 KEG10715.1 - 0.14 12.3 0.2 0.39 10.9 0.2 1.7 1 0 0 1 1 1 0 Necrosis inducing protein-1 DUF2415 PF10313.4 KEG10717.1 - 0.14 11.8 0.0 0.53 10.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) DUF2887 PF11103.3 KEG10718.1 - 0.19 11.3 5.0 0.27 10.7 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2887) AJAP1_PANP_C PF15298.1 KEG10720.1 - 6.2 6.6 11.1 6.6 6.5 4.2 2.7 2 1 0 2 2 2 0 AJAP1/PANP C-terminus DUF3675 PF12428.3 KEG10721.1 - 0.13 12.5 0.3 0.13 12.5 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3675) Glycos_transf_4 PF00953.16 KEG10721.1 - 0.63 9.8 8.2 0.12 12.1 2.7 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 4 CAP59_mtransfer PF11735.3 KEG10722.1 - 1.1e-55 188.5 0.0 2.1e-54 184.2 0.0 2.6 2 1 0 2 2 2 1 Cryptococcal mannosyltransferase 1 Peptidase_S8 PF00082.17 KEG10724.1 - 1e-24 87.1 0.6 4.5e-23 81.8 0.1 2.7 2 1 0 2 2 2 1 Subtilase family HrpB1_HrpK PF09613.5 KEG10724.1 - 0.015 14.7 0.0 0.044 13.2 0.0 1.8 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) Dpy-30 PF05186.8 KEG10726.1 - 1.6e-07 30.6 0.0 2.6e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Dpy-30 motif Pox_MCEL PF03291.11 KEG10728.1 - 9.5e-44 149.6 0.0 1.2e-43 149.3 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme mRNA_cap_enzyme PF01331.14 KEG10728.1 - 3.8e-11 43.0 0.3 4.7e-05 23.1 0.1 3.4 2 1 0 2 2 2 2 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 KEG10728.1 - 1.1e-09 38.5 0.0 2.6e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain CTDII PF01556.13 KEG10729.1 - 1e-26 92.6 1.1 2.2e-21 75.5 0.0 4.0 3 1 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KEG10729.1 - 4.2e-14 52.3 13.1 8.7e-14 51.3 9.1 1.6 1 0 0 1 1 1 1 DnaJ central domain zf-C3HC4_3 PF13920.1 KEG10729.1 - 0.00033 20.2 8.3 0.012 15.2 0.7 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) HypA PF01155.14 KEG10729.1 - 0.00081 19.0 7.5 0.022 14.4 0.4 2.4 1 1 1 2 2 2 2 Hydrogenase expression/synthesis hypA family zf-RING_2 PF13639.1 KEG10729.1 - 0.32 10.8 6.1 2.2 8.1 0.6 2.6 2 0 0 2 2 2 0 Ring finger domain NRDD PF13597.1 KEG10729.1 - 0.43 8.5 2.4 0.27 9.2 0.4 1.4 1 1 1 2 2 2 0 Anaerobic ribonucleoside-triphosphate reductase Lar_restr_allev PF14354.1 KEG10729.1 - 1.3 9.3 8.3 22 5.4 0.0 3.6 1 1 1 2 2 2 0 Restriction alleviation protein Lar zf-RING_5 PF14634.1 KEG10729.1 - 1.7 8.4 7.8 3.6 7.3 1.1 2.6 2 0 0 2 2 2 0 zinc-RING finger domain HHH_5 PF14520.1 KEG10730.1 - 0.00014 21.9 0.0 0.0003 20.8 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.2 KEG10730.1 - 0.0087 15.9 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.18 KEG10730.1 - 0.028 14.0 0.0 0.073 12.7 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif R3H PF01424.17 KEG10731.1 - 6.7e-08 32.1 0.0 1.4e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 R3H domain ADK PF00406.17 KEG10732.1 - 3.1 7.6 7.7 1.2 9.0 1.2 2.5 2 0 0 2 2 2 0 Adenylate kinase Colicin-DNase PF12639.2 KEG10732.1 - 9.1 6.5 10.5 2.7 8.2 0.2 3.2 3 1 0 3 3 3 0 DNase/tRNase domain of colicin-like bacteriocin SET PF00856.23 KEG10733.1 - 0.00011 22.5 0.1 0.00017 21.9 0.1 1.7 1 1 0 1 1 1 1 SET domain Paramyxo_PCT PF14320.1 KEG10736.1 - 0.071 11.9 0.1 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoprotein P region PCT disordered Ribosomal_60s PF00428.14 KEG10737.1 - 8.3e-25 87.0 21.4 1.2e-22 80.1 12.0 2.1 2 0 0 2 2 2 2 60s Acidic ribosomal protein Homeobox_KN PF05920.6 KEG10737.1 - 0.015 14.9 0.0 7.4 6.3 0.0 2.2 2 0 0 2 2 2 0 Homeobox KN domain HTH_26 PF13443.1 KEG10737.1 - 0.043 14.0 0.0 13 6.0 0.0 2.2 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain HTH_19 PF12844.2 KEG10737.1 - 0.066 13.2 0.0 14 5.8 0.0 2.2 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_31 PF13560.1 KEG10737.1 - 0.094 12.9 3.2 9.4 6.5 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain DUF3933 PF13069.1 KEG10737.1 - 0.23 11.1 2.4 13 5.6 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3933) Exo_endo_phos PF03372.18 KEG10738.1 - 1.3e-16 61.2 0.0 4.6e-16 59.5 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.22 KEG10738.1 - 4.3e-11 42.6 0.0 9.4e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain DUF1835 PF08874.5 KEG10738.1 - 0.11 12.4 0.1 6.6 6.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1835) Nucleoside_tran PF01733.13 KEG10739.1 - 3.9e-33 114.9 1.1 9.7e-33 113.6 0.8 1.6 1 1 0 1 1 1 1 Nucleoside transporter UFC1 PF08694.6 KEG10740.1 - 1.3e-66 222.9 0.1 1.5e-66 222.8 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.21 KEG10740.1 - 0.0024 17.3 0.2 0.0029 17.0 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KEG10740.1 - 0.13 12.1 0.1 0.16 11.8 0.1 1.3 1 1 0 1 1 1 0 RWD domain CorA PF01544.13 KEG10741.1 - 1.8e-41 142.1 0.1 2.2e-41 141.7 0.1 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Dynamin_M PF01031.15 KEG10741.1 - 0.099 11.4 0.0 0.34 9.6 0.0 1.7 2 0 0 2 2 2 0 Dynamin central region IQ PF00612.22 KEG10745.1 - 1.5e-08 33.5 20.3 0.00081 18.8 0.1 5.7 5 0 0 5 5 5 4 IQ calmodulin-binding motif Helicase_C PF00271.26 KEG10746.1 - 8.7e-16 57.5 0.3 1.1e-14 53.9 0.0 2.8 2 2 0 2 2 2 1 Helicase conserved C-terminal domain 2OG-FeII_Oxy_3 PF13640.1 KEG10747.1 - 1.6e-13 51.0 0.0 2.9e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KEG10747.1 - 1.5e-07 30.9 0.0 2.7e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.8 KEG10747.1 - 0.00011 22.3 0.0 0.00028 20.9 0.0 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Pox_C4_C10 PF03336.8 KEG10747.1 - 0.0025 16.6 0.0 0.0036 16.1 0.0 1.2 1 0 0 1 1 1 1 Poxvirus C4/C10 protein Methyltransf_18 PF12847.2 KEG10748.1 - 1.1e-05 25.9 0.0 0.00013 22.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEG10748.1 - 0.00019 21.4 1.3 0.00028 20.8 0.9 1.6 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KEG10748.1 - 0.00064 18.9 0.1 0.00093 18.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 KEG10748.1 - 0.0042 16.4 0.0 0.0078 15.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.6 KEG10748.1 - 0.018 13.7 0.0 0.026 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_11 PF08241.7 KEG10748.1 - 0.074 13.5 0.0 0.7 10.4 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain ADK PF00406.17 KEG10749.1 - 2.4e-26 92.4 0.0 4.3e-26 91.6 0.0 1.4 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.1 KEG10749.1 - 9.1e-10 39.4 0.0 3.3e-09 37.5 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 KEG10749.1 - 2.4e-09 37.1 0.0 4.2e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KEG10749.1 - 7.3e-08 32.7 0.0 1.5e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain SKI PF01202.17 KEG10749.1 - 0.0033 17.2 0.1 0.085 12.7 0.0 2.7 1 1 0 1 1 1 1 Shikimate kinase RIIa PF02197.12 KEG10749.1 - 0.0049 16.2 0.2 0.011 15.0 0.1 1.7 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit AAA_28 PF13521.1 KEG10749.1 - 0.0051 16.7 0.0 0.011 15.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEG10749.1 - 0.017 14.8 0.0 0.074 12.8 0.0 1.9 2 1 0 2 2 2 0 Part of AAA domain Zeta_toxin PF06414.7 KEG10749.1 - 0.02 13.9 0.0 0.096 11.7 0.0 2.0 1 1 0 1 1 1 0 Zeta toxin Thymidylate_kin PF02223.12 KEG10749.1 - 0.052 12.9 0.0 3 7.1 0.0 2.7 3 0 0 3 3 3 0 Thymidylate kinase CoaE PF01121.15 KEG10749.1 - 0.082 12.2 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_5 PF07728.9 KEG10749.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) EFhand_Ca_insen PF08726.5 KEG10750.1 - 0.086 12.8 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Ca2+ insensitive EF hand Myosin_head PF00063.16 KEG10751.1 - 2.9e-156 521.4 0.0 6.7e-156 520.2 0.0 1.6 1 1 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.1 KEG10751.1 - 0.01 15.9 0.3 0.079 13.1 0.1 2.6 2 0 0 2 2 2 0 AAA domain HAS-barrel PF09378.5 KEG10751.1 - 0.12 12.2 0.0 0.42 10.5 0.0 1.9 1 0 0 1 1 1 0 HAS barrel domain ASF1_hist_chap PF04729.8 KEG10752.1 - 3.4e-17 62.4 0.0 4.1e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone Sedlin_N PF04628.8 KEG10753.1 - 6.4e-22 77.8 0.0 7.1e-22 77.6 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 KEG10753.1 - 0.017 14.8 0.0 0.021 14.5 0.0 1.1 1 0 0 1 1 1 0 Sybindin-like family Glucosamine_iso PF01182.15 KEG10754.1 - 2.6e-48 164.4 0.0 3.1e-48 164.1 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Penicil_amidase PF01804.13 KEG10755.1 - 1.9e-100 338.0 0.0 2.5e-100 337.6 0.0 1.1 1 0 0 1 1 1 1 Penicillin amidase Tetraspannin PF00335.15 KEG10755.1 - 0.33 10.1 10.2 0.54 9.5 7.1 1.3 1 0 0 1 1 1 0 Tetraspanin family LRR_6 PF13516.1 KEG10757.1 - 0.00011 21.9 12.6 0.013 15.4 0.1 7.0 8 0 0 8 8 8 1 Leucine Rich repeat LRR_4 PF12799.2 KEG10757.1 - 0.0054 16.3 2.3 0.12 12.0 0.2 3.6 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEG10757.1 - 5.1 7.5 9.1 44 4.6 0.0 5.1 7 0 0 7 7 7 0 Leucine Rich Repeat OsmC PF02566.14 KEG10758.1 - 2e-08 34.3 0.2 3.4e-08 33.6 0.1 1.4 1 0 0 1 1 1 1 OsmC-like protein Focal_AT PF03623.8 KEG10759.1 - 0.011 15.1 8.7 0.12 11.8 1.6 2.5 2 0 0 2 2 2 0 Focal adhesion targeting region PPR PF01535.15 KEG10762.1 - 0.0026 17.6 0.5 0.38 10.8 0.0 3.9 4 0 0 4 4 4 1 PPR repeat PPR_2 PF13041.1 KEG10762.1 - 0.0038 17.1 0.0 0.13 12.2 0.0 3.1 3 0 0 3 3 3 1 PPR repeat family COX5A PF02284.11 KEG10762.1 - 0.21 11.5 0.0 0.46 10.4 0.0 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va PPR_3 PF13812.1 KEG10762.1 - 0.33 11.3 2.7 8.8 6.8 0.1 4.5 4 0 0 4 4 4 0 Pentatricopeptide repeat domain zf-CCCH PF00642.19 KEG10763.1 - 0.12 12.0 0.6 0.24 11.1 0.4 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Hamartin PF04388.7 KEG10764.1 - 0.011 14.3 0.6 0.016 13.9 0.4 1.2 1 0 0 1 1 1 0 Hamartin protein WD40 PF00400.27 KEG10764.1 - 0.041 13.7 3.9 1.3 9.0 0.0 4.8 5 1 0 5 5 5 0 WD domain, G-beta repeat DUF3648 PF12364.3 KEG10766.1 - 2.9e-13 50.0 0.2 2.9e-13 50.0 0.1 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3648) NTP_transf_2 PF01909.18 KEG10766.1 - 0.043 14.1 0.1 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain EF-hand_7 PF13499.1 KEG10767.1 - 5.2e-16 58.5 3.9 6.9e-08 32.5 0.4 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KEG10767.1 - 9.6e-13 46.4 2.1 0.00066 18.8 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 KEG10767.1 - 2e-12 45.8 0.8 0.002 17.8 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 KEG10767.1 - 4.6e-11 42.1 2.4 0.0038 16.7 0.0 4.5 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 KEG10767.1 - 1.8e-06 27.0 1.4 0.028 13.7 0.0 3.0 3 0 0 3 3 3 2 EF hand Ras PF00071.17 KEG10768.1 - 1e-52 177.7 0.1 6.9e-52 175.0 0.0 1.9 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KEG10768.1 - 3.3e-14 53.3 0.0 8.5e-14 52.0 0.0 1.6 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEG10768.1 - 1.1e-13 50.7 0.0 3.7e-12 45.8 0.0 2.0 1 1 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KEG10768.1 - 1e-06 28.3 0.0 1.5e-06 27.7 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KEG10768.1 - 0.00026 20.2 0.0 0.00055 19.1 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KEG10768.1 - 0.003 17.5 0.1 0.005 16.7 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KEG10768.1 - 0.013 15.6 0.0 0.031 14.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 KEG10768.1 - 0.015 14.5 0.3 0.028 13.6 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 KEG10768.1 - 0.048 13.1 0.0 0.43 10.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain DAP3 PF10236.4 KEG10768.1 - 0.13 11.2 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DnaJ PF00226.26 KEG10769.1 - 9.5e-16 57.2 1.0 2.8e-15 55.7 0.7 1.9 1 0 0 1 1 1 1 DnaJ domain PUF PF00806.14 KEG10770.1 - 3.9e-50 164.6 9.5 1.5e-06 27.3 0.0 8.7 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.6 KEG10770.1 - 0.049 13.4 1.2 2.4 8.0 0.0 3.3 2 1 0 3 3 3 0 CPL (NUC119) domain HisG PF01634.13 KEG10772.1 - 0.11 12.0 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 ATP phosphoribosyltransferase DUF3082 PF11282.3 KEG10772.1 - 0.21 11.6 5.1 0.072 13.1 1.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3082) Chloroplast_duf PF14476.1 KEG10772.1 - 0.98 8.1 4.2 0.88 8.3 2.3 1.4 1 1 0 1 1 1 0 Petal formation-expressed Tetraspannin PF00335.15 KEG10772.1 - 2.8 7.1 10.7 3.2 6.9 6.9 1.5 1 1 0 1 1 1 0 Tetraspanin family Nucleoplasmin PF03066.10 KEG10774.1 - 0.074 12.5 3.3 0.094 12.2 2.3 1.2 1 0 0 1 1 1 0 Nucleoplasmin LsmAD PF06741.8 KEG10775.1 - 5.2e-25 87.3 1.7 1.1e-24 86.2 1.2 1.6 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.1 KEG10775.1 - 1.2e-15 57.1 0.0 2.1e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain Phage_HK97_TLTM PF06120.6 KEG10775.1 - 0.061 12.6 0.1 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Mito_fiss_reg PF05308.6 KEG10775.1 - 6 6.1 15.5 0.12 11.7 2.9 2.4 2 0 0 2 2 2 0 Mitochondrial fission regulator Paf67 PF10255.4 KEG10777.1 - 0.0096 14.8 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 KEG10777.1 - 0.035 14.0 0.2 0.16 11.9 0.2 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 KEG10777.1 - 0.07 12.7 0.1 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-C3HC4_3 PF13920.1 KEG10778.1 - 5.1e-16 58.0 10.1 1e-15 57.1 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEG10778.1 - 2e-08 34.1 13.1 4.3e-08 33.0 9.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEG10778.1 - 4.2e-05 23.2 12.2 4.2e-05 23.2 8.4 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KEG10778.1 - 9.7e-05 21.9 12.9 0.00017 21.1 8.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 KEG10778.1 - 0.00035 20.0 4.3 0.00092 18.7 3.0 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.1 KEG10778.1 - 0.004 16.8 11.4 0.0089 15.7 7.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-P11 PF03854.9 KEG10778.1 - 0.0073 15.7 8.2 0.015 14.7 5.7 1.5 1 0 0 1 1 1 1 P-11 zinc finger zf-RING_4 PF14570.1 KEG10778.1 - 0.22 11.1 7.8 0.47 10.0 5.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Trichoplein PF13868.1 KEG10779.1 - 1.1e-67 227.8 154.3 1.1e-67 227.8 106.9 2.1 2 0 0 2 2 2 1 Tumour suppressor, Mitostatin DUF2360 PF10152.4 KEG10780.1 - 0.083 13.1 7.9 0.13 12.4 5.5 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) CAF-1_p150 PF11600.3 KEG10780.1 - 0.17 11.2 18.1 0.22 10.8 12.5 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal FLO_LFY PF01698.11 KEG10780.1 - 0.18 10.6 13.6 0.25 10.1 9.4 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein TFIIA PF03153.8 KEG10780.1 - 0.5 10.2 13.4 0.58 9.9 9.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Parvo_coat PF00740.13 KEG10780.1 - 0.98 8.2 7.1 1.2 8.0 4.9 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Suf PF05843.9 KEG10780.1 - 0.98 9.0 8.4 1.6 8.4 5.9 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) NPR3 PF03666.8 KEG10780.1 - 1.3 7.5 6.0 1.6 7.2 4.2 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 U79_P34 PF03064.11 KEG10780.1 - 1.4 8.4 13.5 1.7 8.1 9.4 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 eIF-3_zeta PF05091.7 KEG10780.1 - 1.4 7.4 11.3 1.6 7.2 7.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) BTV_NS2 PF04514.7 KEG10780.1 - 1.7 7.4 10.9 2.2 7.1 7.6 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Peptidase_S64 PF08192.6 KEG10780.1 - 1.7 6.8 5.5 2.1 6.5 3.8 1.0 1 0 0 1 1 1 0 Peptidase family S64 DDHD PF02862.12 KEG10780.1 - 2.3 7.9 9.8 3.1 7.5 6.8 1.2 1 0 0 1 1 1 0 DDHD domain Band_3_cyto PF07565.8 KEG10780.1 - 3.8 6.9 12.9 7.4 5.9 8.9 1.4 1 1 0 1 1 1 0 Band 3 cytoplasmic domain DDRGK PF09756.4 KEG10780.1 - 3.9 6.8 18.1 6.4 6.1 12.5 1.4 1 0 0 1 1 1 0 DDRGK domain Med19 PF10278.4 KEG10780.1 - 4.6 6.8 11.6 7.1 6.2 7.5 1.7 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 DUF4355 PF14265.1 KEG10780.1 - 4.7 7.1 14.2 1.2 9.1 5.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) Zip PF02535.17 KEG10780.1 - 5.9 5.7 6.1 7.2 5.5 4.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.11 KEG10780.1 - 7.6 6.3 7.2 9.7 5.9 5.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region zf-C3HC4_3 PF13920.1 KEG10781.1 - 4e-11 42.3 11.5 4e-11 42.3 8.0 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Ras PF00071.17 KEG10782.1 - 5.3e-21 74.6 0.0 6.3e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEG10782.1 - 0.0058 17.1 0.0 0.023 15.1 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein zf-RING_2 PF13639.1 KEG10785.1 - 3.5e-14 52.3 4.6 4.3e-13 48.8 3.4 2.6 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 KEG10785.1 - 4.4e-08 33.1 6.3 4.4e-08 33.1 4.4 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KEG10785.1 - 1.2e-07 31.3 1.4 1.2e-07 31.3 1.0 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KEG10785.1 - 8.5e-07 28.5 2.6 8.5e-07 28.5 1.8 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEG10785.1 - 2.4e-06 27.0 2.4 6.7e-06 25.6 1.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEG10785.1 - 2.1e-05 24.4 4.0 2.1e-05 24.4 2.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KEG10785.1 - 0.016 15.0 4.6 0.061 13.1 3.2 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 KEG10785.1 - 0.034 14.1 2.0 0.09 12.7 1.4 1.8 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 KEG10785.1 - 0.063 13.0 3.1 0.14 11.8 0.7 2.7 2 1 0 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.1 KEG10785.1 - 0.17 11.4 7.4 0.78 9.3 3.5 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain PHD PF00628.24 KEG10785.1 - 0.53 10.0 2.8 1.3 8.8 2.0 1.7 1 0 0 1 1 1 0 PHD-finger Mito_carr PF00153.22 KEG10786.1 - 2.5e-10 39.9 2.3 3.9e-06 26.4 0.5 2.3 2 0 0 2 2 2 2 Mitochondrial carrier protein COX7C PF02935.11 KEG10786.1 - 0.17 11.6 0.9 0.39 10.5 0.6 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc zf-RanBP PF00641.13 KEG10788.1 - 1.9e-07 30.0 2.7 3.5e-07 29.1 1.9 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others VHS PF00790.14 KEG10788.1 - 5.4e-06 26.0 0.0 7.7e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 VHS domain RrnaAD PF00398.15 KEG10790.1 - 4.7e-60 202.8 0.0 5.8e-60 202.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 KEG10790.1 - 2.6e-10 40.3 0.0 3.8e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEG10790.1 - 2.7e-06 27.9 0.0 4.4e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEG10790.1 - 2e-05 24.2 0.0 3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEG10790.1 - 4.7e-05 23.1 0.0 0.0001 22.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEG10790.1 - 0.00015 22.2 0.0 0.0003 21.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEG10790.1 - 0.00022 20.6 0.0 0.00039 19.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 KEG10790.1 - 0.0012 18.3 0.0 0.002 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.1 KEG10790.1 - 0.0024 18.1 0.0 0.0049 17.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEG10790.1 - 0.0038 17.6 0.0 0.0079 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 KEG10790.1 - 0.012 14.5 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_4 PF02390.12 KEG10790.1 - 0.017 14.1 0.0 0.034 13.1 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Pox_D5 PF03288.11 KEG10790.1 - 0.023 14.9 0.4 0.051 13.8 0.2 1.6 1 0 0 1 1 1 0 Poxvirus D5 protein-like Ubie_methyltran PF01209.13 KEG10790.1 - 0.058 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NodS PF05401.6 KEG10790.1 - 0.072 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) LELP1 PF15042.1 KEG10790.1 - 0.097 12.8 0.4 4.2 7.6 0.2 2.3 2 0 0 2 2 2 0 Late cornified envelope-like proline-rich protein 1 Methyltransf_28 PF02636.12 KEG10790.1 - 0.099 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MFS_1 PF07690.11 KEG10791.1 - 0.002 16.8 3.3 0.002 16.8 2.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Gly-zipper_OmpA PF13436.1 KEG10791.1 - 0.0054 16.3 2.6 0.0085 15.7 1.8 1.2 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain Bacteriocin_IIc PF10439.4 KEG10791.1 - 2.1 8.5 7.8 3.6 7.7 5.4 1.4 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide PNK3P PF08645.6 KEG10793.1 - 2.9e-48 163.3 0.0 5.5e-48 162.4 0.0 1.5 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 KEG10793.1 - 1.1e-16 60.9 0.1 1e-15 57.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KEG10793.1 - 1.6e-07 30.6 0.0 0.00058 19.0 0.0 2.2 2 0 0 2 2 2 2 Zeta toxin AAA_22 PF13401.1 KEG10793.1 - 0.0012 18.9 0.0 0.0024 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEG10793.1 - 0.0059 17.4 0.0 0.015 16.0 0.0 1.8 2 0 0 2 2 1 1 AAA domain MMR_HSR1 PF01926.18 KEG10793.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.1 KEG10793.1 - 0.014 15.3 0.0 0.043 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KEG10793.1 - 0.02 14.7 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KEG10793.1 - 0.042 14.1 0.0 0.075 13.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Viral_helicase1 PF01443.13 KEG10793.1 - 0.051 13.0 0.0 0.08 12.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase tRNA_lig_kinase PF08303.6 KEG10793.1 - 0.056 13.3 0.0 0.082 12.7 0.0 1.2 1 0 0 1 1 1 0 tRNA ligase kinase domain AAA_16 PF13191.1 KEG10793.1 - 0.09 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain NAD_binding_2 PF03446.10 KEG10794.1 - 8.6e-54 181.7 2.7 1.7e-53 180.8 1.9 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KEG10794.1 - 1.2e-36 125.5 0.6 2.2e-36 124.5 0.4 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.14 KEG10794.1 - 5.3e-06 25.7 0.1 2.5e-05 23.5 0.1 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KEG10794.1 - 1.9e-05 25.0 1.5 3.3e-05 24.2 0.1 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 KEG10794.1 - 2.1e-05 24.6 0.1 3.8e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.9 KEG10794.1 - 0.00017 21.0 0.2 0.15 11.4 0.0 2.4 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 KEG10794.1 - 0.00025 20.7 2.5 0.0003 20.4 0.2 2.2 2 2 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.7 KEG10794.1 - 0.0091 15.3 0.9 0.011 15.0 0.1 1.5 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain ApbA PF02558.11 KEG10794.1 - 0.036 13.5 0.0 0.092 12.1 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA START PF01852.14 KEG10795.1 - 8.6e-05 21.9 0.1 0.0002 20.7 0.0 1.6 1 1 0 1 1 1 1 START domain Rubis-subs-bind PF09273.6 KEG10796.1 - 7.4e-07 29.1 0.0 3.3e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding SET PF00856.23 KEG10796.1 - 0.0043 17.3 0.0 0.026 14.8 0.0 2.1 2 1 0 2 2 2 1 SET domain WW PF00397.21 KEG10798.1 - 4.4e-10 39.2 4.5 4.4e-10 39.2 3.1 2.0 3 0 0 3 3 3 1 WW domain zf-CCCH PF00642.19 KEG10798.1 - 1.5e-08 34.0 0.8 2.4e-08 33.4 0.6 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) VWA_CoxE PF05762.9 KEG10800.1 - 0.05 12.7 0.3 0.075 12.1 0.2 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein RINGv PF12906.2 KEG10801.1 - 1.6e-10 40.8 11.3 3.6e-10 39.7 7.8 1.6 1 0 0 1 1 1 1 RING-variant domain Pkinase PF00069.20 KEG10802.1 - 3.2e-71 239.5 0.0 4.2e-71 239.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG10802.1 - 8.6e-35 120.0 0.0 8.2e-34 116.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase DUF2656 PF10847.3 KEG10802.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2656) p450 PF00067.17 KEG10803.1 - 2e-62 211.2 0.1 2.8e-62 210.7 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1289 PF06945.8 KEG10805.1 - 0.14 11.6 0.7 0.4 10.1 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) DEAD PF00270.24 KEG10807.1 - 5.9e-34 116.9 0.0 9.8e-34 116.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KEG10807.1 - 0.00024 21.0 0.0 0.00064 19.5 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KEG10807.1 - 0.049 13.7 0.0 2 8.5 0.0 2.7 3 0 0 3 3 3 0 AAA domain SNF2_N PF00176.18 KEG10807.1 - 0.053 12.2 0.0 0.086 11.6 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain Snf7 PF03357.16 KEG10808.1 - 1.9e-25 89.2 7.3 2.4e-25 88.8 5.1 1.1 1 0 0 1 1 1 1 Snf7 TBPIP PF07106.8 KEG10808.1 - 0.0019 17.7 1.4 0.0019 17.7 1.0 1.6 1 1 1 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) V-SNARE_C PF12352.3 KEG10808.1 - 0.13 12.3 2.1 7.3 6.7 0.1 3.1 2 1 1 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus UPF0184 PF03670.8 KEG10808.1 - 0.83 9.8 5.3 1.3 9.2 0.1 2.9 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0184) Methyltransf_23 PF13489.1 KEG10809.1 - 7.6e-15 54.9 0.0 5.9e-14 52.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEG10809.1 - 7.4e-14 52.0 0.2 7.1e-12 45.6 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEG10809.1 - 1.1e-11 44.3 0.0 7.1e-11 41.6 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KEG10809.1 - 4e-09 36.8 0.0 0.00052 20.4 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 KEG10809.1 - 8.8e-07 28.6 0.0 0.00017 21.1 0.0 3.0 2 2 1 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEG10809.1 - 2.9e-05 24.3 0.1 0.015 15.6 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 KEG10809.1 - 0.0021 18.6 1.4 0.99 10.0 0.0 3.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEG10809.1 - 0.12 12.4 0.0 0.6 10.1 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain TPR_16 PF13432.1 KEG10811.1 - 2.7e-06 27.9 0.7 0.0071 16.9 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 KEG10811.1 - 0.021 15.0 0.5 6.5 7.2 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEG10811.1 - 0.037 14.6 5.0 49 4.9 0.0 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat Ax_dynein_light PF10211.4 KEG10812.1 - 0.0066 16.3 15.6 0.0066 16.3 10.8 9.9 1 1 8 10 10 10 2 Axonemal dynein light chain Reo_sigmaC PF04582.7 KEG10812.1 - 0.28 10.2 41.8 0.23 10.5 0.6 6.3 1 1 4 7 7 7 0 Reovirus sigma C capsid protein Pkinase PF00069.20 KEG10813.1 - 1.5e-65 220.9 0.0 2e-37 128.7 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEG10813.1 - 2.8e-27 95.4 0.1 2.7e-20 72.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KEG10813.1 - 0.069 12.8 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 KEG10813.1 - 0.076 12.0 0.1 0.34 9.9 0.1 1.9 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Carn_acyltransf PF00755.15 KEG10815.1 - 3.9e-152 507.3 0.0 4.6e-152 507.1 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Peptidase_M24 PF00557.19 KEG10815.1 - 0.061 12.8 0.0 0.37 10.3 0.0 2.2 1 1 0 1 1 1 0 Metallopeptidase family M24 DAGAT PF03982.8 KEG10817.1 - 2.8e-23 82.0 0.0 5.3e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol acyltransferase SPC25 PF06703.6 KEG10817.1 - 0.22 11.0 3.1 0.16 11.5 0.4 2.0 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DAGAT PF03982.8 KEG10818.1 - 1.7e-23 82.8 0.3 6.1e-23 80.9 0.0 2.0 2 0 0 2 2 2 1 Diacylglycerol acyltransferase RNA_pol_L_2 PF13656.1 KEG10819.1 - 1.5e-20 72.3 0.0 2.4e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KEG10819.1 - 1.5e-09 36.8 0.0 2.3e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain CD24 PF14984.1 KEG10820.1 - 0.035 13.9 3.1 0.077 12.8 2.1 1.6 1 0 0 1 1 1 0 CD24 protein DUF543 PF04418.7 KEG10821.1 - 1.5e-22 79.3 0.0 1.9e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) TctA PF01970.11 KEG10821.1 - 0.093 11.1 0.0 3.6 5.8 0.0 2.0 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctA family TBCA PF02970.11 KEG10822.1 - 0.17 11.9 1.0 0.26 11.3 0.7 1.2 1 0 0 1 1 1 0 Tubulin binding cofactor A zf-HC5HC2H PF13771.1 KEG10823.1 - 1.5e-16 60.2 7.7 1.5e-16 60.2 5.3 2.4 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 KEG10823.1 - 3.5e-12 46.2 12.3 7.4e-12 45.2 8.5 1.6 1 0 0 1 1 1 1 PHD-zinc-finger like domain Myc_N PF01056.13 KEG10823.1 - 0.057 12.5 6.2 0.021 14.0 2.2 1.6 1 1 0 1 1 1 0 Myc amino-terminal region zf-Apc11 PF12861.2 KEG10823.1 - 5.6 6.8 13.6 0.033 14.0 2.0 2.5 2 1 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger Robl_LC7 PF03259.12 KEG10824.1 - 0.0063 16.0 0.2 0.26 10.8 0.1 2.2 1 1 0 1 1 1 1 Roadblock/LC7 domain LT-IIB PF06453.6 KEG10824.1 - 0.038 13.6 0.1 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) 60KD_IMP PF02096.15 KEG10825.1 - 2e-15 56.9 0.0 2.9e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein DUF2484 PF10658.4 KEG10825.1 - 0.07 13.2 1.7 0.17 12.0 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2484) DUF4632 PF15451.1 KEG10825.1 - 0.089 12.7 0.4 0.24 11.3 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) Pkinase PF00069.20 KEG10826.1 - 1e-11 44.4 0.1 5.5e-06 25.7 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEG10826.1 - 0.00032 19.8 0.0 0.00051 19.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG10826.1 - 0.12 11.3 0.0 0.19 10.6 0.0 1.3 1 1 0 1 1 1 0 Kinase-like DUF599 PF04654.7 KEG10827.1 - 0.086 11.9 0.0 0.088 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF599 DnaJ PF00226.26 KEG10828.1 - 1.6e-15 56.5 1.8 3.6e-15 55.4 0.3 2.1 2 0 0 2 2 2 1 DnaJ domain PIN_4 PF13638.1 KEG10829.1 - 0.24 11.5 4.1 0.29 11.2 2.8 1.1 1 0 0 1 1 1 0 PIN domain DUF501 PF04417.7 KEG10829.1 - 0.24 11.2 5.2 0.32 10.8 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF501) Pox_A_type_inc PF04508.7 KEG10829.1 - 0.42 10.5 7.6 4.1 7.4 0.5 3.1 2 1 0 2 2 2 0 Viral A-type inclusion protein repeat DUF4610 PF15384.1 KEG10829.1 - 0.7 9.3 4.7 0.77 9.2 3.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4610) Atg14 PF10186.4 KEG10829.1 - 9.8 5.0 12.1 9.5 5.0 8.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DSPc PF00782.15 KEG10830.1 - 2e-21 75.9 0.2 2.7e-21 75.5 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KEG10830.1 - 4e-05 23.0 0.2 5.7e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 KEG10830.1 - 0.041 13.2 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Init_tRNA_PT PF04179.7 KEG10830.1 - 0.12 11.1 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase zf-SNAP50_C PF12251.3 KEG10831.1 - 5.5e-58 195.5 0.2 7.3e-58 195.1 0.1 1.2 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal Phage_tail_X PF05489.7 KEG10831.1 - 0.056 12.9 0.2 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 Phage Tail Protein X WD40 PF00400.27 KEG10832.1 - 1.6e-35 119.6 0.1 3.4e-10 39.4 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat Katanin_con80 PF13925.1 KEG10832.1 - 8.9e-33 113.3 0.7 1.2e-32 112.8 0.5 1.2 1 0 0 1 1 1 1 con80 domain of Katanin Nup160 PF11715.3 KEG10832.1 - 0.00071 17.8 0.2 0.0047 15.1 0.1 2.2 1 1 2 3 3 3 1 Nucleoporin Nup120/160 DUF3312 PF11768.3 KEG10832.1 - 0.059 11.5 0.0 4.1 5.4 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3312) ALIX_LYPXL_bnd PF13949.1 KEG10833.1 - 0.0025 16.8 11.6 0.0038 16.2 2.7 2.6 2 1 0 2 2 2 2 ALIX V-shaped domain binding to HIV V-SNARE PF05008.10 KEG10833.1 - 0.014 15.5 0.9 0.014 15.5 0.6 3.6 4 1 0 4 4 4 0 Vesicle transport v-SNARE protein N-terminus DUF1181 PF06680.6 KEG10833.1 - 0.016 14.8 0.1 0.033 13.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1181) CENP-F_leu_zip PF10473.4 KEG10833.1 - 0.022 14.6 3.0 0.022 14.6 2.1 4.1 4 1 0 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sec34 PF04136.10 KEG10833.1 - 0.032 13.9 0.7 0.15 11.7 0.3 2.2 2 0 0 2 2 2 0 Sec34-like family Med4 PF10018.4 KEG10833.1 - 0.18 11.2 0.1 0.18 11.2 0.1 2.6 3 1 0 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF2408 PF10303.4 KEG10833.1 - 0.2 11.7 8.5 6.3 6.9 2.4 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF148 PF02520.12 KEG10833.1 - 0.46 10.2 4.1 0.46 10.2 0.0 2.9 3 1 0 3 3 3 0 Domain of unknown function DUF148 DUF812 PF05667.6 KEG10833.1 - 7.5 4.9 13.4 0.58 8.6 0.5 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF812) ParcG PF10274.4 KEG10834.1 - 1.2e-76 256.6 0.1 1.5e-76 256.4 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein RNase_H PF00075.19 KEG10835.1 - 0.00063 20.0 0.0 0.00079 19.7 0.0 1.2 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 KEG10835.1 - 0.0069 16.1 0.3 0.014 15.1 0.1 1.6 2 0 0 2 2 2 1 Reverse transcriptase-like Peptidase_C2 PF00648.16 KEG10836.1 - 1.1e-46 159.1 0.0 1.7e-46 158.6 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 KEG10836.1 - 7.1e-33 112.6 0.3 3.1e-32 110.6 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1935) Citrus_P18 PF05520.6 KEG10836.1 - 0.24 10.9 0.0 0.4 10.1 0.0 1.3 1 0 0 1 1 1 0 Citrus tristeza virus P18 protein Peptidase_C2 PF00648.16 KEG10837.1 - 1.6e-41 142.3 0.0 2e-41 141.9 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 KEG10837.1 - 4.5e-29 100.4 0.0 7.9e-29 99.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.16 KEG10838.1 - 7.7e-38 130.1 0.0 1.1e-37 129.7 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 KEG10838.1 - 8.1e-32 109.2 0.2 1.5e-31 108.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.16 KEG10839.1 - 1.3e-50 172.1 0.0 1.8e-50 171.6 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 KEG10839.1 - 4.5e-31 106.9 0.0 8.6e-31 106.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Calpain_III PF01067.17 KEG10839.1 - 0.00035 20.2 0.0 0.00073 19.2 0.0 1.6 1 1 0 1 1 1 1 Calpain large subunit, domain III CTDII PF01556.13 KEG10840.1 - 1.3e-27 95.5 2.8 1.2e-20 73.2 0.1 3.3 3 0 0 3 3 3 3 DnaJ C terminal domain DnaJ PF00226.26 KEG10840.1 - 6.3e-24 83.4 0.7 1.2e-23 82.5 0.5 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KEG10840.1 - 1.5e-08 34.5 23.7 3.1e-08 33.5 16.4 1.5 1 0 0 1 1 1 1 DnaJ central domain GCC2_GCC3 PF07699.8 KEG10840.1 - 0.015 14.8 2.1 0.015 14.8 1.4 2.9 1 1 1 2 2 2 0 GCC2 and GCC3 zf-RING_2 PF13639.1 KEG10841.1 - 9.4e-14 50.9 8.9 1.8e-13 50.0 6.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KEG10841.1 - 7.8e-07 28.6 4.3 1.2e-06 28.0 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEG10841.1 - 1.2e-06 28.4 8.0 2e-06 27.7 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KEG10841.1 - 2.4e-06 27.5 2.7 4.7e-06 26.6 1.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KEG10841.1 - 0.00016 21.3 2.8 0.00036 20.2 1.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 KEG10841.1 - 0.00046 19.7 7.0 0.00077 19.0 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEG10841.1 - 0.009 15.7 7.2 0.014 15.1 5.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.3 KEG10841.1 - 0.39 10.7 3.7 0.8 9.7 2.6 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 KEG10841.1 - 0.92 9.1 6.8 2.5 7.7 5.0 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 KEG10841.1 - 1.7 8.5 5.3 5.5 6.9 3.6 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Cmc1 PF08583.5 KEG10842.1 - 4.4e-05 23.1 2.8 6.2e-05 22.6 2.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like SEN1_N PF12726.2 KEG10842.1 - 0.031 12.3 0.1 0.038 12.0 0.1 1.2 1 1 0 1 1 1 0 SEN1 N terminal OHCU_decarbox PF09349.5 KEG10842.1 - 0.12 12.6 0.2 17 5.6 0.0 2.1 1 1 1 2 2 2 0 OHCU decarboxylase Skp1_POZ PF03931.10 KEG10843.1 - 6.9e-05 22.8 0.0 0.0071 16.4 0.0 2.2 2 0 0 2 2 2 2 Skp1 family, tetramerisation domain TPR_12 PF13424.1 KEG10845.1 - 7.5e-07 29.0 0.9 0.012 15.5 0.1 2.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 KEG10845.1 - 9.5e-05 21.9 0.1 0.067 12.9 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEG10845.1 - 0.00039 20.1 0.1 0.014 15.2 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 KEG10845.1 - 0.0079 15.8 0.2 0.022 14.3 0.0 1.8 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 KEG10845.1 - 0.0098 15.4 0.1 0.22 11.2 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_21 PF09976.4 KEG10845.1 - 0.012 15.5 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat IQ PF00612.22 KEG10845.1 - 0.055 13.1 0.0 0.18 11.4 0.0 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif TPR_10 PF13374.1 KEG10845.1 - 0.14 12.1 0.6 3.4 7.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat SRP-alpha_N PF04086.8 KEG10845.1 - 6.6 6.0 10.8 0.46 9.8 2.3 2.2 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Nop14 PF04147.7 KEG10846.1 - 1.2 7.0 6.8 1.7 6.4 4.7 1.1 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 KEG10846.1 - 1.9 7.9 9.1 3.9 6.9 6.3 1.4 1 0 0 1 1 1 0 Nucleoplasmin Ribosomal_L30 PF00327.15 KEG10847.1 - 0.0054 16.2 0.0 0.014 15.0 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e ICAP-1_inte_bdg PF10480.4 KEG10847.1 - 0.21 11.3 2.4 1.9 8.2 0.0 2.2 2 0 0 2 2 2 0 Beta-1 integrin binding protein Rhomboid PF01694.17 KEG10848.1 - 0.00046 20.2 4.1 0.00046 20.2 2.8 1.8 2 1 0 2 2 2 1 Rhomboid family WD40 PF00400.27 KEG10850.1 - 2e-14 52.8 8.6 5.8e-06 25.9 0.2 7.9 10 0 0 10 10 10 4 WD domain, G-beta repeat EF-hand_8 PF13833.1 KEG10850.1 - 0.099 12.2 0.1 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair NAPRTase PF04095.11 KEG10851.1 - 1.5e-63 214.3 0.0 2e-63 213.9 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family WW PF00397.21 KEG10852.1 - 0.012 15.4 0.5 0.012 15.4 0.3 2.2 2 0 0 2 2 2 0 WW domain Sporozoite_P67 PF05642.6 KEG10852.1 - 0.39 8.5 3.2 0.81 7.4 2.2 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF1777 PF08648.7 KEG10852.1 - 1 9.0 45.5 0.32 10.7 24.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 KEG10852.1 - 1.1 7.6 25.7 0.95 7.8 12.0 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 TFIIA PF03153.8 KEG10852.1 - 1.1 9.0 18.4 1.2 8.9 3.2 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Skp1 PF01466.14 KEG10853.1 - 3.6e-19 68.5 0.3 5.2e-19 68.0 0.2 1.2 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 KEG10853.1 - 0.011 15.7 0.0 1.6 8.9 0.0 2.3 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain E1-E2_ATPase PF00122.15 KEG10854.1 - 1.1e-48 165.3 0.3 1.1e-48 165.3 0.2 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KEG10854.1 - 1e-34 119.6 3.7 1e-34 119.6 2.6 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KEG10854.1 - 1.2e-15 58.5 0.0 1.2e-14 55.2 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEG10854.1 - 2.1e-14 54.1 0.0 6.4e-13 49.2 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KEG10854.1 - 8.9e-05 22.1 0.2 0.00016 21.3 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KEG10854.1 - 0.00011 21.5 0.0 0.00028 20.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KEG10854.1 - 0.00018 21.3 0.0 0.00039 20.3 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit EF-hand_10 PF14788.1 KEG10854.1 - 0.078 12.6 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 EF hand PSP1 PF04468.7 KEG10855.1 - 6.8e-11 42.0 1.7 1.1e-10 41.3 0.1 2.1 2 0 0 2 2 2 1 PSP1 C-terminal conserved region Pkinase PF00069.20 KEG10856.1 - 7.3e-48 162.9 0.0 1.1e-47 162.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG10856.1 - 1e-26 93.5 0.0 1.7e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.1 KEG10856.1 - 1.9e-14 53.1 15.8 3.2e-06 26.7 0.7 3.4 1 1 4 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 KEG10856.1 - 2.7e-14 52.3 0.5 1.2e-06 27.9 0.0 3.9 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEG10856.1 - 1.7e-09 36.3 3.5 0.0052 16.6 0.0 5.9 4 1 1 5 5 5 2 Leucine Rich Repeat zf-B_box PF00643.19 KEG10856.1 - 3.5e-06 26.7 18.0 0.0022 17.8 2.0 2.5 2 0 0 2 2 2 2 B-box zinc finger LRR_7 PF13504.1 KEG10856.1 - 1.3e-05 24.6 3.9 0.0078 16.2 0.0 4.4 4 0 0 4 4 3 1 Leucine rich repeat LRR_6 PF13516.1 KEG10856.1 - 0.00057 19.6 0.2 0.63 10.2 0.0 4.6 4 0 0 4 4 4 1 Leucine Rich repeat zf-UBR PF02207.15 KEG10856.1 - 0.00059 19.5 0.6 0.00059 19.5 0.4 2.7 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) Kinase-like PF14531.1 KEG10856.1 - 0.0015 17.5 0.0 0.0027 16.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like C1_2 PF03107.11 KEG10856.1 - 0.012 15.6 6.9 0.012 15.6 4.8 2.7 2 0 0 2 2 2 0 C1 domain APH PF01636.18 KEG10856.1 - 0.1 12.3 0.7 0.51 10.0 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family YokU PF14122.1 KEG10857.1 - 0.18 11.5 0.0 0.18 11.5 0.0 2.3 3 0 0 3 3 3 0 YokU-like protein Zn_Tnp_IS1595 PF12760.2 KEG10857.1 - 8.4 6.2 14.3 6.8 6.5 2.0 3.4 3 0 0 3 3 3 0 Transposase zinc-ribbon domain WD40 PF00400.27 KEG10858.1 - 1.3e-32 110.4 14.8 1.9e-07 30.6 0.1 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 KEG10858.1 - 2.8e-05 23.9 0.0 0.0046 16.6 0.0 2.9 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Kelch_6 PF13964.1 KEG10858.1 - 0.063 13.4 2.5 17 5.7 0.0 4.1 5 0 0 5 5 5 0 Kelch motif Nbas_N PF15492.1 KEG10858.1 - 0.077 12.0 0.2 17 4.4 0.0 3.0 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Gp37_Gp68 PF07505.6 KEG10858.1 - 0.081 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Phage protein Gp37/Gp68 IKI3 PF04762.7 KEG10858.1 - 0.57 7.9 1.5 2.9 5.5 0.1 2.2 1 1 1 3 3 3 0 IKI3 family UQ_con PF00179.21 KEG10859.1 - 3.2e-23 81.7 0.1 1.7e-22 79.3 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme SET PF00856.23 KEG10862.1 - 3.6e-08 33.8 0.1 3.2e-05 24.2 0.1 2.3 2 0 0 2 2 2 2 SET domain TPR_1 PF00515.23 KEG10862.1 - 0.00055 19.4 0.2 0.0015 18.0 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEG10862.1 - 0.031 14.1 0.2 0.11 12.4 0.2 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat PGC7_Stella PF15549.1 KEG10862.1 - 0.12 12.3 2.6 0.11 12.4 0.4 1.9 2 0 0 2 2 2 0 PGC7/Stella/Dppa3 domain DUF581 PF04570.9 KEG10862.1 - 9.2 5.6 13.1 16 4.9 3.8 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF581) Ssl1 PF04056.9 KEG10863.1 - 4.2e-24 85.2 0.0 5.7e-11 42.3 0.0 2.1 1 1 1 2 2 2 2 Ssl1-like BRF1 PF07741.8 KEG10864.1 - 0.63 10.3 4.0 10 6.3 1.4 2.3 1 1 1 2 2 2 0 Brf1-like TBP-binding domain Vpu PF00558.14 KEG10864.1 - 1.2 8.7 3.5 2.8 7.5 1.1 2.3 2 0 0 2 2 2 0 Vpu protein SpoU_methylase PF00588.14 KEG10865.1 - 2.6e-14 53.3 0.0 4.1e-13 49.4 0.0 2.1 1 1 0 1 1 1 1 SpoU rRNA Methylase family FixQ PF05545.6 KEG10865.1 - 0.09 12.4 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Peptidase_M8 PF01457.11 KEG10866.1 - 1.9e-102 343.2 1.3 2.3e-102 343.0 0.9 1.0 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M10 PF00413.19 KEG10866.1 - 0.054 13.2 0.0 0.093 12.4 0.0 1.3 1 0 0 1 1 1 0 Matrixin Peptidase_M8 PF01457.11 KEG10867.1 - 1.6e-121 406.2 0.0 2e-121 405.9 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin G10 PF01125.12 KEG10868.1 - 1.1e-53 180.6 1.7 2.2e-53 179.7 1.2 1.5 1 1 0 1 1 1 1 G10 protein DUF4632 PF15451.1 KEG10868.1 - 0.024 14.5 0.1 0.024 14.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) DUF3177 PF11375.3 KEG10869.1 - 0.12 11.8 0.8 0.14 11.5 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3177) Dynein_light PF01221.13 KEG10870.1 - 2.4e-23 81.8 0.0 3.6e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 DUF2332 PF10094.4 KEG10870.1 - 0.0012 17.9 0.0 0.0016 17.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2332) Nol1_Nop2_Fmu PF01189.12 KEG10871.1 - 5.9e-23 81.6 0.0 5e-19 68.7 0.0 3.3 1 1 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 KEG10871.1 - 0.025 14.5 0.0 0.061 13.3 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase Y_phosphatase PF00102.22 KEG10872.1 - 2e-50 171.3 0.0 2.4e-50 171.0 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KEG10872.1 - 2e-06 27.4 0.0 4.3e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 KEG10872.1 - 2.8e-05 24.1 0.0 6.1e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 KEG10872.1 - 8.3e-05 22.8 0.0 0.00017 21.9 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PDZ PF00595.19 KEG10873.1 - 0.091 12.9 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) Choline_transpo PF04515.7 KEG10875.1 - 1.2e-83 280.6 31.2 1.2e-83 280.6 21.6 2.6 1 1 1 2 2 2 1 Plasma-membrane choline transporter EF-hand_7 PF13499.1 KEG10876.1 - 3.3e-19 68.7 2.3 1e-10 41.5 0.8 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KEG10876.1 - 3.1e-18 63.6 8.2 5.8e-06 25.2 0.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 KEG10876.1 - 4.1e-15 54.2 5.3 0.0018 17.9 0.2 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KEG10876.1 - 6.7e-13 47.3 8.3 2.8e-06 26.3 0.3 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 KEG10876.1 - 1.6e-10 40.4 7.7 0.00018 21.0 0.5 3.8 2 2 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KEG10876.1 - 4.2e-05 23.5 0.0 0.27 11.2 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KEG10876.1 - 0.00024 20.7 0.4 2.3 7.9 0.0 3.1 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KEG10876.1 - 0.034 14.0 0.0 9.4 6.2 0.0 2.5 2 1 0 2 2 2 0 EF-hand domain EF-hand_2 PF09068.6 KEG10876.1 - 0.09 12.8 0.0 4.4 7.3 0.0 2.3 2 0 0 2 2 2 0 EF hand Dockerin_1 PF00404.13 KEG10876.1 - 0.32 10.7 8.8 4.4 7.1 0.1 3.3 3 0 0 3 3 3 0 Dockerin type I repeat EF-hand_1 PF00036.27 KEG10877.1 - 0.01 15.0 0.0 0.61 9.5 0.0 3.1 3 0 0 3 3 3 0 EF hand EF-hand_6 PF13405.1 KEG10877.1 - 0.03 14.2 0.0 0.15 12.0 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain Pkinase PF00069.20 KEG10878.1 - 1.6e-48 165.1 0.0 2.3e-48 164.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG10878.1 - 1.6e-18 66.7 0.0 3.5e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEG10878.1 - 0.005 16.6 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KEG10878.1 - 0.024 13.7 0.0 0.047 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KEG10878.1 - 0.068 12.5 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 RIO1 family 5_3_exonuc PF01367.15 KEG10879.1 - 2e-18 66.5 0.0 3.5e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold 5_3_exonuc_N PF02739.11 KEG10879.1 - 9.6e-16 57.6 1.0 2.5e-13 49.7 0.7 3.0 1 1 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain HHH_2 PF12826.2 KEG10879.1 - 0.039 13.8 0.0 0.093 12.6 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif zf-MYND PF01753.13 KEG10881.1 - 5.9e-05 22.8 14.4 0.00012 21.9 10.0 1.5 1 0 0 1 1 1 1 MYND finger T5orf172 PF10544.4 KEG10881.1 - 0.045 14.1 0.2 0.065 13.6 0.1 1.3 1 0 0 1 1 1 0 T5orf172 domain DUF2777 PF10949.3 KEG10882.1 - 0.036 13.7 0.0 0.077 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2777) YlqD PF11068.3 KEG10882.1 - 0.15 12.0 5.9 0.47 10.4 4.1 1.8 1 0 0 1 1 1 0 YlqD protein TMF_TATA_bd PF12325.3 KEG10882.1 - 0.25 11.1 14.4 1 9.1 3.2 3.8 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding GAS PF13851.1 KEG10882.1 - 0.84 8.7 17.1 0.13 11.4 7.1 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding PUF PF00806.14 KEG10883.1 - 1.1e-50 166.2 5.0 3.3e-07 29.4 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CoA_trans PF01144.18 KEG10883.1 - 0.073 12.2 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Coenzyme A transferase DUF607 PF04678.8 KEG10884.1 - 1.5e-31 109.7 2.3 5.1e-31 107.9 1.6 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF607 DUF2157 PF09925.4 KEG10884.1 - 0.047 13.2 0.0 0.068 12.7 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Proteasome PF00227.21 KEG10885.1 - 3.6e-65 218.8 0.0 5.2e-65 218.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KEG10885.1 - 7.1e-10 38.0 0.1 1.6e-09 36.8 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RecA PF00154.16 KEG10885.1 - 0.0054 15.8 0.2 0.077 12.0 0.0 2.0 2 0 0 2 2 2 1 recA bacterial DNA recombination protein IQ PF00612.22 KEG10887.1 - 4.9e-14 50.5 83.0 0.006 16.1 2.4 14.7 14 0 0 14 14 14 10 IQ calmodulin-binding motif ECIST_Cterm PF14784.1 KEG10887.1 - 0.0057 16.6 1.3 0.13 12.2 0.4 3.4 2 0 0 2 2 2 1 C-terminal domain of the ECSIT protein LRR_6 PF13516.1 KEG10888.1 - 7e-11 41.0 3.3 0.014 15.3 0.0 4.4 4 0 0 4 4 4 3 Leucine Rich repeat LRR_4 PF12799.2 KEG10888.1 - 1.6e-06 27.6 0.2 0.0023 17.4 0.0 3.4 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEG10888.1 - 3.1e-05 23.4 1.1 13 6.3 0.0 4.9 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 KEG10888.1 - 0.044 13.9 2.1 1e+02 3.8 0.0 4.6 4 0 0 4 4 4 0 Leucine rich repeat LRR_8 PF13855.1 KEG10888.1 - 0.071 12.8 0.5 2.4 8.0 0.1 2.7 1 1 0 1 1 1 0 Leucine rich repeat L51_S25_CI-B8 PF05047.11 KEG10889.1 - 0.0059 16.3 0.1 0.0094 15.6 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain COG5 PF10392.4 KEG10891.1 - 4.6e-10 39.5 1.6 4.6e-10 39.5 1.1 4.1 5 0 0 5 5 5 1 Golgi transport complex subunit 5 COG2 PF06148.6 KEG10891.1 - 6.9e-05 22.7 3.2 0.00032 20.5 0.5 3.2 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 UME PF08064.8 KEG10891.1 - 0.1 12.5 0.2 9.5 6.2 0.0 3.3 3 0 0 3 3 3 0 UME (NUC010) domain HGTP_anticodon2 PF12745.2 KEG10893.1 - 0.026 13.6 2.9 0.054 12.6 2.0 1.6 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs MMR_HSR1 PF01926.18 KEG10894.1 - 1.6e-06 28.0 0.0 2.4e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 KEG10894.1 - 2.3e-06 26.9 0.1 8.6e-06 25.1 0.0 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KEG10894.1 - 4.1e-06 25.7 0.1 0.011 14.4 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 KEG10894.1 - 1.7e-05 25.3 0.0 3.4e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 KEG10894.1 - 0.0007 19.4 0.0 0.0017 18.1 0.0 2.0 1 1 0 1 1 1 1 Dynamin family AAA_17 PF13207.1 KEG10894.1 - 0.008 16.9 0.6 0.028 15.2 0.4 2.2 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 KEG10894.1 - 0.0081 15.3 0.1 0.089 11.9 0.0 2.2 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region Ras PF00071.17 KEG10894.1 - 0.0086 15.4 0.0 0.022 14.1 0.0 1.7 1 1 0 1 1 1 1 Ras family T2SE PF00437.15 KEG10894.1 - 0.031 13.1 0.1 0.062 12.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.22 KEG10894.1 - 0.059 13.6 0.1 0.36 11.1 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_18 PF13238.1 KEG10894.1 - 0.077 13.2 1.0 0.3 11.4 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KEG10894.1 - 0.1 12.1 0.1 0.19 11.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 KEG10894.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain CobU PF02283.11 KEG10894.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase FtsK_SpoIIIE PF01580.13 KEG10894.1 - 0.14 11.6 0.1 0.25 10.8 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.1 KEG10894.1 - 0.26 11.6 1.9 0.75 10.0 1.3 1.8 1 1 0 1 1 1 0 AAA domain APC2 PF08672.6 KEG10896.1 - 0.012 15.8 0.1 0.041 14.1 0.0 2.0 2 0 0 2 2 2 0 Anaphase promoting complex (APC) subunit 2 FlxA PF14282.1 KEG10897.1 - 0.011 15.7 0.4 0.033 14.1 0.3 1.9 1 1 0 1 1 1 0 FlxA-like protein IncA PF04156.9 KEG10897.1 - 0.024 14.2 0.6 0.041 13.4 0.4 1.3 1 0 0 1 1 1 0 IncA protein SGT1 PF07093.6 KEG10898.1 - 0.007 14.7 6.6 0.014 13.8 0.0 2.1 1 1 1 2 2 2 1 SGT1 protein WD40 PF00400.27 KEG10899.1 - 4.3e-09 35.8 20.1 0.017 15.0 0.0 9.1 10 0 0 10 10 10 4 WD domain, G-beta repeat DUF3312 PF11768.3 KEG10899.1 - 0.0052 15.0 0.0 0.011 13.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) BBS2_Mid PF14783.1 KEG10899.1 - 0.078 12.7 0.0 4.6 7.0 0.0 3.1 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region BSP_II PF05432.6 KEG10899.1 - 0.28 10.4 2.4 1.1 8.4 2.2 1.5 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Patatin PF01734.17 KEG10900.1 - 2.3e-22 79.9 0.0 6.4e-22 78.4 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase DUF3336 PF11815.3 KEG10900.1 - 1.7e-20 73.0 0.3 1.2e-19 70.2 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) NUDIX PF00293.23 KEG10901.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 NUDIX domain LRR_8 PF13855.1 KEG10902.1 - 9.2e-08 31.7 3.7 1.4e-06 27.9 0.2 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 KEG10902.1 - 1.2e-05 24.7 4.7 0.00057 19.4 0.9 3.0 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEG10902.1 - 0.0016 18.2 4.1 0.56 10.4 0.4 3.6 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_6 PF13516.1 KEG10902.1 - 0.0087 16.0 2.5 1.1 9.5 0.0 3.2 2 2 0 2 2 2 1 Leucine Rich repeat ATP-gua_Ptrans PF00217.14 KEG10902.1 - 0.04 13.2 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 ATP:guanido phosphotransferase, C-terminal catalytic domain DUF2526 PF10735.4 KEG10902.1 - 0.082 12.9 0.1 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2526) LRR_7 PF13504.1 KEG10902.1 - 0.16 12.2 6.4 3.1 8.3 0.4 3.9 3 1 0 3 3 3 0 Leucine rich repeat Pkinase PF00069.20 KEG10903.1 - 1.2e-46 158.9 0.0 9.4e-36 123.2 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Beta_helix PF13229.1 KEG10903.1 - 1.4e-45 154.8 25.3 2e-20 73.1 2.9 3.9 1 1 3 4 4 4 4 Right handed beta helix region Pkinase_Tyr PF07714.12 KEG10903.1 - 3.8e-33 114.6 0.0 1.6e-27 96.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase NosD PF05048.8 KEG10903.1 - 1.5e-23 83.1 0.3 5.6e-11 42.0 0.0 2.4 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) zf-B_box PF00643.19 KEG10903.1 - 8.8e-06 25.5 7.4 4e-05 23.4 5.2 2.2 1 0 0 1 1 1 1 B-box zinc finger DUF1565 PF07602.6 KEG10903.1 - 2.4e-05 23.6 1.7 0.0001 21.5 1.2 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1565) Kinase-like PF14531.1 KEG10903.1 - 4.9e-05 22.4 0.0 0.00024 20.1 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KEG10903.1 - 0.0065 16.2 0.0 0.035 13.8 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pectate_lyase_3 PF12708.2 KEG10903.1 - 0.12 12.5 3.6 0.22 11.6 1.6 2.3 1 1 0 1 1 1 0 Pectate lyase superfamily protein BolA PF01722.13 KEG10906.1 - 9.5e-14 51.1 0.0 1.3e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein KOW PF00467.24 KEG10907.1 - 1.1e-06 28.1 1.6 1.9e-06 27.3 0.4 2.1 2 1 0 2 2 2 1 KOW motif LRR_4 PF12799.2 KEG10909.1 - 1.6e-13 49.9 11.8 4.5e-05 22.9 0.1 4.7 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEG10909.1 - 4e-10 38.2 11.0 0.094 12.8 0.4 6.4 6 0 0 6 6 6 4 Leucine Rich Repeat LRR_7 PF13504.1 KEG10909.1 - 3e-09 35.5 8.1 0.29 11.4 0.5 6.7 6 0 0 6 6 6 3 Leucine rich repeat LRR_8 PF13855.1 KEG10909.1 - 6.6e-09 35.4 9.5 0.00074 19.2 0.4 3.7 2 1 1 3 3 3 3 Leucine rich repeat LRR_6 PF13516.1 KEG10909.1 - 1.4e-08 33.8 7.8 0.051 13.6 0.3 5.5 6 0 0 6 6 6 2 Leucine Rich repeat LRR_9 PF14580.1 KEG10909.1 - 2.2e-07 30.5 0.2 8.4e-06 25.4 0.0 2.3 1 1 1 2 2 2 2 Leucine-rich repeat RTC PF01137.16 KEG10910.1 - 5.9e-52 175.7 0.1 6.8e-52 175.5 0.1 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 KEG10910.1 - 6.1e-27 93.6 0.1 9.8e-27 92.9 0.1 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Pro_isomerase PF00160.16 KEG10911.1 - 2.5e-12 47.2 0.0 4.2e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ost4 PF10215.4 KEG10911.1 - 0.024 14.0 0.7 0.05 13.1 0.5 1.4 1 0 0 1 1 1 0 Oligosaccaryltransferase Pkinase PF00069.20 KEG10912.1 - 5.7e-57 192.8 0.0 6.6e-57 192.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG10912.1 - 1.4e-19 70.1 0.0 2.2e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEG10912.1 - 6.7e-08 32.5 0.0 7.1e-05 22.6 0.0 2.5 1 1 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 KEG10912.1 - 0.0038 16.8 0.0 0.006 16.1 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 KEG10912.1 - 0.029 13.4 0.0 0.062 12.3 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KEG10912.1 - 0.037 13.3 0.1 0.3 10.3 0.0 2.1 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL UCH PF00443.24 KEG10913.1 - 2.8e-49 167.6 0.3 4.8e-49 166.8 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEG10913.1 - 1.1e-20 74.3 0.0 1.6e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.1 KEG10913.1 - 1.7e-17 63.5 0.0 5e-14 52.2 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-specific protease C-terminal USP7_ICP0_bdg PF12436.3 KEG10913.1 - 6.7e-11 41.8 0.3 1.8e-10 40.4 0.0 1.8 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 UDPGT PF00201.13 KEG10914.1 - 5e-15 55.0 0.0 2.2e-13 49.6 0.0 2.7 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 KEG10914.1 - 0.027 14.1 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain DUF3232 PF11554.3 KEG10914.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3232) NUC202 PF08166.7 KEG10916.1 - 0.029 14.2 0.0 0.17 11.7 0.0 2.1 2 0 0 2 2 2 0 NUC202 domain DUF1491 PF07372.7 KEG10916.1 - 0.061 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1491) Yos1 PF08571.5 KEG10917.1 - 4.2e-28 97.2 0.0 5e-28 97.0 0.0 1.1 1 0 0 1 1 1 1 Yos1-like zf-RING_2 PF13639.1 KEG10918.1 - 3e-17 62.1 20.8 1.1e-09 37.8 5.1 3.5 3 0 0 3 3 3 3 Ring finger domain zf-rbx1 PF12678.2 KEG10918.1 - 4.1e-08 33.2 13.9 5.8e-05 23.1 2.8 3.5 3 0 0 3 3 3 2 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KEG10918.1 - 8.5e-08 31.7 17.2 0.00024 20.6 3.8 3.4 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEG10918.1 - 1.3e-06 28.0 22.5 2.2e-05 24.0 5.0 3.6 3 1 0 3 3 3 2 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KEG10918.1 - 2.8e-06 27.2 19.5 0.0013 18.7 4.4 3.6 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) IQ PF00612.22 KEG10918.1 - 0.00013 21.2 3.1 0.00013 21.2 2.1 2.4 2 0 0 2 2 2 1 IQ calmodulin-binding motif zf-RING_UBOX PF13445.1 KEG10918.1 - 0.0063 16.2 1.1 0.0063 16.2 0.8 3.6 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.20 KEG10918.1 - 0.008 15.8 21.8 0.015 14.9 4.5 4.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF4048 PF13257.1 KEG10918.1 - 0.12 11.9 5.5 0.2 11.2 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4048) Sporozoite_P67 PF05642.6 KEG10918.1 - 0.53 8.0 3.5 0.72 7.6 2.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Rtf2 PF04641.7 KEG10918.1 - 0.87 8.7 11.5 1.4 8.0 0.5 3.1 2 1 1 3 3 3 0 Rtf2 RING-finger BphX PF06139.7 KEG10919.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 BphX-like CDC37_N PF03234.9 KEG10919.1 - 6.6 7.0 6.5 0.75 10.0 1.0 2.0 3 0 0 3 3 3 0 Cdc37 N terminal kinase binding CENP-F_leu_zip PF10473.4 KEG10920.1 - 0.031 14.1 1.8 1.1 9.1 0.6 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Claudin_2 PF13903.1 KEG10921.1 - 0.0081 15.8 5.9 0.0062 16.2 3.5 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 KEG10921.1 - 0.028 14.0 15.8 0.043 13.4 10.9 1.3 1 0 0 1 1 1 0 Amastin surface glycoprotein RRM_1 PF00076.17 KEG10923.1 - 9.9e-24 82.7 0.5 6.8e-14 51.2 0.0 3.4 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG10923.1 - 8.7e-17 60.8 0.2 2.4e-08 33.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PLRV_ORF5 PF01690.12 KEG10923.1 - 0.43 9.6 0.0 0.43 9.6 0.0 2.9 3 0 0 3 3 3 0 Potato leaf roll virus readthrough protein FAD_binding_1 PF00667.15 KEG10924.1 - 1.7e-34 119.2 0.0 3e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KEG10924.1 - 1.5e-18 67.1 0.1 8.5e-18 64.7 0.1 2.2 1 1 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KEG10924.1 - 5.4e-09 36.5 0.0 3.4e-08 34.0 0.0 2.3 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KEG10924.1 - 6.3e-05 23.0 0.0 0.00024 21.1 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Cortex-I_coil PF09304.5 KEG10925.1 - 0.0077 16.2 1.1 0.013 15.5 0.8 1.3 1 0 0 1 1 1 1 Cortexillin I, coiled coil SDP_N PF12278.3 KEG10925.1 - 0.077 12.6 0.2 0.18 11.3 0.1 1.7 1 0 0 1 1 1 0 Sex determination protein N terminal Dermcidin PF15291.1 KEG10925.1 - 2.5 8.3 5.9 0.77 9.9 1.7 1.9 2 0 0 2 2 2 0 Dermcidin, antibiotic peptide UBN2 PF14223.1 KEG10926.1 - 0.02 14.6 0.2 0.035 13.8 0.2 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF3824 PF12868.2 KEG10926.1 - 0.058 14.3 0.0 0.072 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) DUF1876 PF08962.6 KEG10926.1 - 0.11 12.2 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1876) zf-DHHC PF01529.15 KEG10927.1 - 4.8e-23 81.4 9.7 4.8e-23 81.4 6.7 2.2 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF2181 PF10223.4 KEG10928.1 - 1.7e-09 37.3 0.0 2.1e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2181) P34-Arc PF04045.9 KEG10929.1 - 4.3e-27 94.9 0.1 5.3e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc PNP_UDP_1 PF01048.15 KEG10931.1 - 1.9e-47 161.2 0.3 2.2e-47 160.9 0.2 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily PP-binding_2 PF14573.1 KEG10931.1 - 0.0087 16.0 0.0 0.023 14.7 0.0 1.7 1 1 0 1 1 1 1 Acyl-carrier Mito_carr PF00153.22 KEG10932.1 - 4.6e-24 83.9 4.0 4.7e-09 35.8 0.2 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF3131 PF11329.3 KEG10932.1 - 0.0092 14.6 0.0 0.12 10.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3131) DUF3624 PF12292.3 KEG10932.1 - 0.77 10.1 4.8 0.35 11.2 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3624) RRM_1 PF00076.17 KEG10933.1 - 3.6e-09 36.1 0.0 9.9e-09 34.7 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG10933.1 - 2.8e-08 33.5 0.0 9.6e-08 31.8 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG10933.1 - 1.5e-05 24.7 0.0 4.4e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1042 PF06294.6 KEG10934.1 - 8.5e-13 48.1 0.0 2.5e-12 46.6 0.0 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1042) CAMSAP_CH PF11971.3 KEG10934.1 - 2.1e-05 24.0 0.0 4.1e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain Med3 PF11593.3 KEG10934.1 - 0.035 13.3 3.5 1.4 8.0 1.0 2.4 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Ribosomal_60s PF00428.14 KEG10934.1 - 0.09 13.1 5.6 0.41 11.0 3.9 2.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein DnaJ PF00226.26 KEG10935.1 - 1.3e-08 34.4 0.3 2.8e-08 33.3 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain Lipoprotein_6 PF01441.14 KEG10938.1 - 3.3 7.5 8.9 3 7.6 0.7 2.8 3 0 0 3 3 3 0 Lipoprotein DUF2617 PF10936.3 KEG10941.1 - 0.082 12.4 0.8 1.6 8.2 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF2617 AMP-binding PF00501.23 KEG10943.1 - 5.6e-56 189.7 0.3 8.8e-56 189.0 0.2 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEG10943.1 - 0.02 15.8 0.3 0.072 14.0 0.0 2.1 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain FeoA PF04023.9 KEG10943.1 - 0.054 13.4 0.1 0.32 10.9 0.0 2.2 2 0 0 2 2 2 0 FeoA domain Radial_spoke PF04712.7 KEG10944.1 - 1.5e-145 485.7 15.5 7e-144 480.2 9.8 2.2 1 1 0 1 1 1 1 Radial spokehead-like protein DUF2553 PF10830.3 KEG10944.1 - 0.12 12.8 0.3 1.9 9.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2553) Pkinase PF00069.20 KEG10945.1 - 9.4e-79 264.2 0.0 1.6e-78 263.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG10945.1 - 2.6e-44 151.2 0.0 5.7e-44 150.1 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Arm PF00514.18 KEG10945.1 - 2.5e-11 42.9 0.0 0.00018 21.2 0.0 5.3 6 0 0 6 6 6 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KEG10945.1 - 1.3e-10 41.4 0.1 0.0016 18.6 0.0 4.2 4 1 1 5 5 5 2 HEAT repeats HEAT_EZ PF13513.1 KEG10945.1 - 5.2e-07 29.9 0.2 0.27 11.8 0.0 5.2 4 1 1 5 5 5 1 HEAT-like repeat HEAT PF02985.17 KEG10945.1 - 2.1e-06 27.3 0.1 2.1 8.6 0.0 5.8 7 0 0 7 7 6 2 HEAT repeat Kinase-like PF14531.1 KEG10945.1 - 9.8e-06 24.7 0.0 1.8e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 KEG10945.1 - 0.00051 19.1 0.1 0.0011 18.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEG10945.1 - 0.00096 18.9 0.0 0.015 15.0 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KEG10945.1 - 0.0016 17.7 0.1 0.0035 16.7 0.1 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.17 KEG10945.1 - 0.0055 16.0 4.9 0.014 14.7 1.2 2.6 2 1 0 2 2 2 1 RIO1 family Seadorna_VP7 PF07387.6 KEG10945.1 - 0.074 11.8 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Alba PF01918.16 KEG10946.1 - 6.4e-11 41.6 0.4 1.1e-10 40.9 0.3 1.4 1 0 0 1 1 1 1 Alba Rpp20 PF12328.3 KEG10946.1 - 0.0074 15.9 6.0 0.021 14.4 3.5 2.0 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 KEG10947.1 - 5.1e-14 51.6 1.2 2.4e-13 49.4 0.1 2.0 2 0 0 2 2 2 1 Alba Rpp20 PF12328.3 KEG10947.1 - 0.0017 18.0 2.4 0.02 14.5 1.7 2.1 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P CYTH PF01928.16 KEG10947.1 - 0.037 13.6 0.1 0.037 13.6 0.1 1.1 1 0 0 1 1 1 0 CYTH domain NAD_binding_1 PF00175.16 KEG10949.1 - 8e-28 97.1 0.0 1.5e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KEG10949.1 - 8.7e-25 86.7 0.0 1.4e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KEG10949.1 - 7.8e-06 25.8 0.0 0.00038 20.4 0.0 2.2 1 1 0 2 2 2 1 Ferric reductase NAD binding domain Flavi_NS4B PF01349.12 KEG10950.1 - 0.034 13.0 0.0 0.044 12.7 0.0 1.1 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4B HECT PF00632.20 KEG10951.1 - 0.0089 15.2 0.0 0.66 9.0 0.0 2.2 2 0 0 2 2 2 2 HECT-domain (ubiquitin-transferase) MKT1_C PF12246.3 KEG10951.1 - 0.12 11.3 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication AAA PF00004.24 KEG10952.1 - 9.7e-42 142.2 0.0 2.1e-41 141.2 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 KEG10952.1 - 7.6e-07 29.1 0.0 1.5e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KEG10952.1 - 5.3e-06 26.6 0.2 0.00059 19.9 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KEG10952.1 - 4.9e-05 23.0 0.2 0.00019 21.1 0.0 2.1 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KEG10952.1 - 5.4e-05 23.2 0.0 0.00034 20.6 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 KEG10952.1 - 0.00025 20.0 0.0 0.00043 19.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 KEG10952.1 - 0.0003 19.9 0.0 0.00055 19.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KEG10952.1 - 0.0022 17.9 0.0 0.0042 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEG10952.1 - 0.003 18.3 0.1 0.009 16.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KEG10952.1 - 0.0052 16.6 0.0 0.0095 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KEG10952.1 - 0.0069 15.9 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KEG10952.1 - 0.0074 15.9 0.2 0.41 10.2 0.1 2.5 1 1 1 2 2 2 1 NACHT domain AAA_19 PF13245.1 KEG10952.1 - 0.0089 15.7 0.6 0.018 14.7 0.4 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 KEG10952.1 - 0.0093 15.9 0.3 0.068 13.1 0.1 2.2 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KEG10952.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 KEG10952.1 - 0.013 15.8 0.0 0.033 14.4 0.0 1.8 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.17 KEG10952.1 - 0.015 15.4 0.0 0.038 14.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase KaiC PF06745.8 KEG10952.1 - 0.023 13.8 0.2 0.52 9.3 0.1 2.3 1 1 1 2 2 2 0 KaiC NB-ARC PF00931.17 KEG10952.1 - 0.035 12.9 0.0 0.062 12.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.1 KEG10952.1 - 0.037 13.4 0.7 1.8 7.8 0.2 2.4 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KEG10952.1 - 0.042 12.9 0.0 0.072 12.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.4 KEG10952.1 - 0.058 12.3 0.2 0.11 11.4 0.2 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TIP49 PF06068.8 KEG10952.1 - 0.065 11.9 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.16 KEG10952.1 - 0.088 11.9 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.13 KEG10952.1 - 0.1 12.0 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase tRNA-synt_1 PF00133.17 KEG10954.1 - 1.4e-30 105.9 0.0 2.8e-19 68.5 0.0 3.1 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KEG10954.1 - 1.3e-19 70.1 0.0 7.1e-10 38.0 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KEG10954.1 - 1.4e-14 54.1 0.0 3.3e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 KEG10954.1 - 2.1e-06 27.0 0.0 4.4e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain GST_C_2 PF13410.1 KEG10955.1 - 0.032 14.1 0.0 0.11 12.3 0.0 2.0 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SpoU_methylase PF00588.14 KEG10956.1 - 6.1e-23 81.2 0.0 1.4e-22 80.1 0.0 1.6 1 0 0 1 1 1 1 SpoU rRNA Methylase family WW PF00397.21 KEG10957.1 - 8.1e-09 35.1 0.2 1.3e-08 34.4 0.1 1.3 1 0 0 1 1 1 1 WW domain Transferase PF02458.10 KEG10957.1 - 0.16 10.3 6.6 0.22 9.9 0.2 2.3 2 0 0 2 2 2 0 Transferase family Reo_sigmaC PF04582.7 KEG10957.1 - 1.4 8.0 8.3 1.6 7.8 0.5 3.1 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Sod_Fe_C PF02777.13 KEG10958.1 - 9.1e-31 105.8 0.6 2.3e-30 104.5 0.4 1.7 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KEG10958.1 - 2.9e-16 59.5 0.1 7.4e-16 58.1 0.1 1.8 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Complex1_LYR_2 PF13233.1 KEG10959.1 - 2.4e-15 56.9 0.4 9.5e-15 54.9 0.3 1.9 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KEG10959.1 - 0.068 12.9 0.6 0.2 11.4 0.4 1.8 1 1 0 1 1 1 0 Complex 1 protein (LYR family) CHCH PF06747.8 KEG10962.1 - 0.99 9.4 3.5 1.5 8.8 2.4 1.4 1 0 0 1 1 1 0 CHCH domain Inhibitor_Mig-6 PF11555.3 KEG10963.1 - 0.059 13.7 1.6 0.066 13.6 1.1 1.2 1 0 0 1 1 1 0 EGFR receptor inhibitor Mig-6 LCE PF14672.1 KEG10963.1 - 0.24 11.8 4.3 0.31 11.5 2.9 1.3 1 0 0 1 1 1 0 Late cornified envelope DAO PF01266.19 KEG10965.1 - 3.4e-45 154.5 0.0 4.6e-45 154.0 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEG10965.1 - 8.1e-05 22.5 0.0 0.00023 21.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KEG10965.1 - 0.004 17.0 0.0 0.045 13.6 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEG10965.1 - 0.013 14.4 0.1 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 KEG10965.1 - 0.034 13.2 0.2 0.073 12.1 0.2 1.7 1 1 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 KEG10965.1 - 0.037 12.6 0.2 0.053 12.1 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_2 PF00890.19 KEG10965.1 - 0.042 12.6 0.3 0.076 11.8 0.2 1.6 1 1 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 KEG10965.1 - 0.044 12.8 0.0 0.11 11.6 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Mqo PF06039.10 KEG10965.1 - 0.071 11.2 0.0 0.1 10.7 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) TrkA_N PF02254.13 KEG10965.1 - 0.09 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Reprolysin_5 PF13688.1 KEG10965.1 - 0.099 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 SEP PF08059.8 KEG10967.1 - 4.4e-07 30.1 0.0 2.3e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 SEP domain TPR_MLP1_2 PF07926.7 KEG10967.1 - 0.034 13.8 4.3 0.057 13.1 3.0 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Tho2 PF11262.3 KEG10967.1 - 0.49 9.3 2.6 0.89 8.5 1.8 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 TylF PF05711.6 KEG10968.1 - 2.7e-27 95.4 0.2 3.9e-27 94.9 0.1 1.1 1 0 0 1 1 1 1 Macrocin-O-methyltransferase (TylF) Methyltransf_24 PF13578.1 KEG10968.1 - 7.1e-13 49.3 0.3 3.9e-12 46.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain CmcI PF04989.7 KEG10968.1 - 0.13 11.5 0.0 0.26 10.5 0.0 1.5 1 0 0 1 1 1 0 Cephalosporin hydroxylase KH_1 PF00013.24 KEG10969.1 - 0.01 15.4 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 0 KH domain KH_3 PF13014.1 KEG10969.1 - 0.037 13.6 0.0 0.082 12.5 0.0 1.6 1 0 0 1 1 1 0 KH domain L27_1 PF09058.5 KEG10969.1 - 0.099 12.5 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 L27_1 TMF_TATA_bd PF12325.3 KEG10969.1 - 5.2 6.8 6.1 3.9 7.2 1.1 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding AIRS_C PF02769.17 KEG10970.1 - 3.9e-18 65.8 0.0 8e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.19 KEG10970.1 - 2e-06 27.9 0.3 6.2e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain BCS1_N PF08740.6 KEG10971.1 - 2.7e-35 121.6 0.4 4e-35 121.1 0.3 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 KEG10971.1 - 9.3e-09 35.5 0.0 0.00039 20.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KEG10971.1 - 0.0094 15.6 0.0 0.031 14.0 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 KEG10971.1 - 0.012 16.4 0.1 0.047 14.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 KEG10971.1 - 0.025 14.1 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 KEG10971.1 - 0.086 11.7 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.1 KEG10971.1 - 0.09 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KEG10971.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 KEG10971.1 - 0.13 11.2 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 KEG10971.1 - 0.17 10.5 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Pribosyltran_N PF13793.1 KEG10972.1 - 5.2e-39 132.5 0.1 4.8e-38 129.4 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KEG10972.1 - 3.7e-29 101.7 3.5 6.2e-29 101.0 1.1 2.0 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KEG10972.1 - 4.5e-11 42.5 0.1 1.3e-10 41.0 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KEG10972.1 - 0.0002 20.6 0.2 0.00043 19.5 0.1 1.6 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase Pyr_redox_2 PF07992.9 KEG10973.1 - 3.2e-27 95.7 0.0 1.1e-26 93.9 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEG10973.1 - 6.3e-09 36.1 2.5 3.2e-08 33.8 0.5 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEG10973.1 - 2.4e-05 24.4 0.4 0.24 11.4 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEG10973.1 - 0.00058 18.8 3.4 0.36 9.6 0.1 3.4 3 1 0 3 3 3 3 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEG10973.1 - 0.0082 16.1 0.0 0.41 10.6 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain mRNA_cap_enzyme PF01331.14 KEG10974.1 - 3.9e-09 36.4 0.7 2e-08 34.1 0.5 2.0 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain AAA_17 PF13207.1 KEG10974.1 - 1.1e-05 26.1 0.0 3.5e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KEG10974.1 - 4e-05 23.9 0.0 0.0001 22.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KEG10974.1 - 0.00014 20.9 0.0 0.0021 17.1 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin ADK PF00406.17 KEG10974.1 - 0.00032 20.6 0.0 0.001 18.9 0.0 1.7 1 1 1 2 2 2 1 Adenylate kinase mRNA_cap_C PF03919.10 KEG10974.1 - 0.002 18.3 0.4 0.0078 16.5 0.0 2.3 2 1 0 2 2 2 1 mRNA capping enzyme, C-terminal domain Thymidylate_kin PF02223.12 KEG10974.1 - 0.0069 15.7 0.1 0.55 9.5 0.0 2.4 1 1 1 2 2 2 1 Thymidylate kinase AAA_33 PF13671.1 KEG10974.1 - 0.014 15.2 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain DNA_ligase_A_M PF01068.16 KEG10974.1 - 0.04 13.2 0.1 7.2 5.9 0.0 2.5 1 1 1 2 2 2 0 ATP dependent DNA ligase domain SRP54 PF00448.17 KEG10974.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Asr PF06392.6 KEG10974.1 - 0.15 12.4 2.1 0.39 11.1 1.5 1.7 1 0 0 1 1 1 0 Acid shock protein repeat PAM2 PF07145.10 KEG10974.1 - 0.35 10.4 3.9 0.85 9.2 2.7 1.6 1 0 0 1 1 1 0 Ataxin-2 C-terminal region LicD PF04991.8 KEG10975.1 - 3.2e-12 47.0 0.0 5.3e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 LicD family CPSF_A PF03178.10 KEG10976.1 - 9.5e-58 195.7 0.0 1.5e-57 195.0 0.0 1.3 1 0 0 1 1 1 1 CPSF A subunit region Peptidase_C97 PF05903.9 KEG10977.1 - 1.2e-17 64.1 0.2 1.9e-17 63.4 0.2 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF3872 PF12988.2 KEG10977.1 - 0.052 13.0 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3872) WLM PF08325.5 KEG10979.1 - 4.9e-57 192.8 0.2 3e-36 125.0 0.2 2.5 2 1 0 2 2 2 2 WLM domain zf-RanBP PF00641.13 KEG10979.1 - 4.9e-06 25.5 21.6 0.0063 15.6 0.1 5.0 5 0 0 5 5 5 3 Zn-finger in Ran binding protein and others DUF45 PF01863.12 KEG10979.1 - 9.2e-06 25.5 3.8 0.003 17.3 0.8 2.4 2 0 0 2 2 2 2 Protein of unknown function DUF45 zf-ribbon_3 PF13248.1 KEG10979.1 - 0.0037 16.4 0.5 0.0037 16.4 0.4 3.7 3 0 0 3 3 3 1 zinc-ribbon domain PHD_2 PF13831.1 KEG10979.1 - 0.82 9.0 14.1 2.6 7.4 0.4 4.3 4 0 0 4 4 4 0 PHD-finger Cript PF10235.4 KEG10979.1 - 6.2 7.2 10.0 19 5.7 0.3 2.5 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT Pep_deformylase PF01327.16 KEG10982.1 - 1.5e-21 76.4 0.0 2e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase Fer4_2 PF12797.2 KEG10982.1 - 0.053 13.4 0.5 0.14 12.1 0.3 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4 PF00037.22 KEG10982.1 - 0.067 12.8 1.2 0.13 11.9 0.9 1.4 1 0 0 1 1 1 0 4Fe-4S binding domain DnaJ PF00226.26 KEG10984.1 - 1.4e-22 79.1 0.8 2.8e-22 78.2 0.5 1.5 1 0 0 1 1 1 1 DnaJ domain Tmemb_185A PF10269.4 KEG10984.1 - 1.3e-08 34.7 14.1 1.3e-08 34.7 9.8 2.5 2 1 1 3 3 3 2 Transmembrane Fragile-X-F protein TRAP_alpha PF03896.11 KEG10984.1 - 0.11 11.5 0.1 0.21 10.5 0.1 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Aminotran_1_2 PF00155.16 KEG10986.1 - 0.012 14.5 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II DDRGK PF09756.4 KEG10987.1 - 8.7e-22 77.4 36.9 6.2e-19 68.1 0.4 3.4 1 1 3 4 4 4 2 DDRGK domain VirE PF05272.6 KEG10987.1 - 0.0074 15.7 0.3 0.011 15.1 0.2 1.2 1 0 0 1 1 1 1 Virulence-associated protein E Macoilin PF09726.4 KEG10987.1 - 5.1 5.2 21.5 6.9 4.8 14.9 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF2362 PF10154.4 KEG10987.1 - 9.7 4.7 10.8 14 4.2 7.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) Pkinase PF00069.20 KEG10988.1 - 6.7e-38 130.3 0.0 1.5e-30 106.2 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEG10988.1 - 9.7e-17 60.8 0.0 2.7e-15 56.1 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG10988.1 - 0.0092 14.9 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Polysacc_synt_3 PF13440.1 KEG10989.1 - 0.12 11.7 0.3 0.16 11.4 0.0 1.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Doppel PF11466.3 KEG10991.1 - 0.064 12.8 1.0 0.13 11.8 0.7 1.5 1 0 0 1 1 1 0 Prion-like protein Doppel DUF3995 PF13160.1 KEG10991.1 - 0.11 12.5 2.0 0.11 12.5 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3995) Grp1_Fun34_YaaH PF01184.14 KEG10992.1 - 1.9e-43 148.2 16.4 2.3e-43 147.9 11.4 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Grp1_Fun34_YaaH PF01184.14 KEG10993.1 - 2.6e-46 157.5 9.4 3.5e-46 157.1 6.5 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DFF-C PF09033.5 KEG10993.1 - 0.15 11.8 0.9 0.23 11.2 0.6 1.2 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain zf-CCCH PF00642.19 KEG10994.1 - 1.3e-05 24.7 9.6 3.3e-05 23.4 1.9 2.9 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KEG10994.1 - 6.4 6.9 8.0 20 5.4 2.6 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type SET PF00856.23 KEG10995.1 - 0.0063 16.8 0.0 0.031 14.5 0.0 2.1 2 1 1 3 3 3 2 SET domain Chordopox_G3 PF06129.7 KEG10996.1 - 0.052 13.6 0.0 0.14 12.3 0.0 1.7 2 0 0 2 2 2 0 Chordopoxvirus G3 protein OAD_gamma PF04277.8 KEG10996.1 - 7 7.1 9.2 0.44 10.9 0.1 2.8 2 1 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain TTL PF03133.10 KEG10997.1 - 3.6e-69 232.9 0.0 5.1e-69 232.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 KEG10997.1 - 0.00079 18.3 0.0 0.004 15.9 0.0 1.9 2 0 0 2 2 2 1 YheC/D like ATP-grasp Pkinase PF00069.20 KEG10998.1 - 6.2e-53 179.6 0.0 8.8e-53 179.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG10998.1 - 1.4e-36 125.8 0.0 2.4e-36 125.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 KEG10998.1 - 2.9e-08 33.8 0.0 5.7e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 KEG10998.1 - 4.5e-08 32.3 0.0 1.6e-07 30.5 0.0 1.7 1 1 1 2 2 2 1 Kinase-like PH_4 PF15404.1 KEG10998.1 - 0.088 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.1 KEG10998.1 - 0.33 11.2 3.1 0.7 10.1 0.7 2.5 2 1 0 2 2 2 0 Pleckstrin homology domain MCM PF00493.18 KEG10999.1 - 1.3e-83 280.6 0.0 1.8e-83 280.0 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 KEG10999.1 - 3e-07 29.8 0.1 3.5e-05 23.0 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KEG10999.1 - 4.3e-06 26.5 0.0 7e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KEG10999.1 - 0.12 12.0 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KEG10999.1 - 0.12 11.8 0.0 0.71 9.3 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain rRNA_processing PF08524.6 KEG11000.1 - 0.013 15.3 0.1 0.018 14.7 0.1 1.2 1 0 0 1 1 1 0 rRNA processing IU_nuc_hydro PF01156.14 KEG11000.1 - 0.12 11.5 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Inosine-uridine preferring nucleoside hydrolase HrpF PF06266.7 KEG11000.1 - 0.19 11.8 0.8 0.81 9.8 0.1 2.0 1 1 0 2 2 2 0 HrpF protein Rad51 PF08423.6 KEG11002.1 - 4.5e-135 448.4 0.1 6.4e-135 447.9 0.1 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.16 KEG11002.1 - 7.2e-13 48.2 0.2 9.1e-13 47.9 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.1 KEG11002.1 - 1.4e-09 37.6 0.0 2.1e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KEG11002.1 - 1.2e-07 31.1 0.0 2e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 KaiC HHH_5 PF14520.1 KEG11002.1 - 1.2e-06 28.5 0.5 3e-06 27.2 0.3 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain DnaB_C PF03796.10 KEG11002.1 - 0.038 12.8 0.2 0.085 11.7 0.1 1.6 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain TPR_11 PF13414.1 KEG11003.1 - 9.5e-20 70.0 9.1 5.9e-15 54.6 3.6 2.3 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 KEG11003.1 - 3.5e-14 51.4 10.8 2e-05 24.1 0.2 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KEG11003.1 - 2.4e-13 49.0 5.8 6.9e-05 22.2 0.1 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KEG11003.1 - 9.2e-10 38.9 15.7 3e-06 27.7 4.5 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEG11003.1 - 2.9e-09 36.7 23.8 3.7e-05 23.5 3.4 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 KEG11003.1 - 3.1e-07 29.6 0.5 0.29 11.0 0.0 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 KEG11003.1 - 1.2e-06 28.2 3.4 0.00012 21.9 1.3 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KEG11003.1 - 2.5e-06 27.6 12.0 0.01 16.3 1.4 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEG11003.1 - 4.2e-06 27.0 7.9 6.1e-05 23.2 2.3 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEG11003.1 - 5.4e-05 22.6 3.8 0.079 12.7 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 KEG11003.1 - 0.00019 21.1 8.4 0.0029 17.4 2.3 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 KEG11003.1 - 0.002 17.9 13.7 0.95 9.4 1.1 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat UPF0121 PF03661.8 KEG11003.1 - 0.055 12.6 8.7 0.093 11.9 6.0 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0121) Apc3 PF12895.2 KEG11003.1 - 0.069 13.2 3.7 0.085 12.9 1.3 2.0 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 KEG11003.1 - 0.89 9.7 4.1 2 8.5 2.6 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat GTPase_Cys_C PF12631.2 KEG11004.1 - 0.032 14.6 4.0 0.032 14.6 2.7 2.8 2 0 0 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE DUF4460 PF14687.1 KEG11004.1 - 0.033 13.9 2.3 0.068 12.9 1.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4460) DUF4253 PF14062.1 KEG11004.1 - 0.11 12.1 4.5 0.28 10.8 1.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4253) IL6 PF00489.12 KEG11004.1 - 0.21 11.1 8.4 0.068 12.7 0.4 2.5 2 1 0 2 2 2 0 Interleukin-6/G-CSF/MGF family MIF4G PF02854.14 KEG11005.1 - 5.5e-12 45.5 4.1 8.2e-12 44.9 0.4 2.5 2 0 0 2 2 2 1 MIF4G domain CaMKII_AD PF08332.5 KEG11005.1 - 0.0064 16.3 0.1 0.02 14.7 0.0 1.8 2 0 0 2 2 2 1 Calcium/calmodulin dependent protein kinase II Association Spt20 PF12090.3 KEG11005.1 - 0.09 12.1 6.7 0.69 9.2 0.8 2.3 2 0 0 2 2 2 0 Spt20 family BAF1_ABF1 PF04684.8 KEG11005.1 - 1.6 7.5 20.7 0.02 13.7 5.2 2.3 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Suf PF05843.9 KEG11005.1 - 5.1 6.7 11.5 9.7 5.8 3.6 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Actin PF00022.14 KEG11006.1 - 1.2e-86 290.6 0.0 1.9e-86 289.9 0.0 1.3 1 1 0 1 1 1 1 Actin EF-hand_7 PF13499.1 KEG11007.1 - 0.023 14.8 0.0 0.12 12.5 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.27 KEG11007.1 - 0.11 11.8 0.0 2.5 7.6 0.0 2.9 3 0 0 3 3 3 0 EF hand DUF4444 PF14563.1 KEG11007.1 - 0.35 10.2 1.7 0.41 10.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4444) NIF PF03031.13 KEG11008.1 - 1.4e-06 28.0 0.0 2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase WH2 PF02205.15 KEG11009.1 - 0.0017 17.8 2.3 0.57 9.8 0.1 3.6 4 0 0 4 4 4 1 WH2 motif Phospho_p8 PF10195.4 KEG11009.1 - 0.0078 16.0 3.1 0.027 14.3 2.1 2.1 1 1 0 1 1 1 1 DNA-binding nuclear phosphoprotein p8 Med9 PF07544.8 KEG11009.1 - 0.026 14.2 1.4 0.026 14.2 1.0 1.8 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 XhlA PF10779.4 KEG11009.1 - 0.35 10.8 5.7 3.7 7.5 0.3 2.5 2 0 0 2 2 2 0 Haemolysin XhlA DUF2058 PF09831.4 KEG11009.1 - 0.64 9.8 5.7 7.5 6.3 0.2 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) Atg14 PF10186.4 KEG11009.1 - 0.64 8.9 4.7 0.32 9.8 0.2 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Mito_fiss_reg PF05308.6 KEG11009.1 - 3.5 6.9 9.5 0.084 12.2 1.8 1.9 1 1 1 2 2 2 0 Mitochondrial fission regulator DivIC PF04977.10 KEG11009.1 - 7.2 6.1 8.4 0.32 10.5 0.6 2.3 2 0 0 2 2 2 0 Septum formation initiator RabGAP-TBC PF00566.13 KEG11010.1 - 7.6e-06 25.5 0.5 7.6e-06 25.5 0.3 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain HCaRG PF07258.9 KEG11011.1 - 0.0028 17.2 0.0 0.0034 16.9 0.0 1.1 1 0 0 1 1 1 1 HCaRG protein Excalibur PF05901.6 KEG11011.1 - 3 8.2 4.8 7.4 7.0 3.3 1.7 1 0 0 1 1 1 0 Excalibur calcium-binding domain 2OG-FeII_Oxy PF03171.15 KEG11012.1 - 9.1e-09 35.5 0.0 2.6e-08 34.0 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Actin PF00022.14 KEG11013.1 - 1.7e-89 300.0 0.0 2.7e-89 299.3 0.0 1.2 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KEG11013.1 - 0.0084 14.7 0.0 0.024 13.2 0.0 1.8 2 1 0 2 2 2 1 MreB/Mbl protein DUF1796 PF08795.5 KEG11014.1 - 1.7e-47 161.1 0.0 3.6e-47 160.1 0.0 1.6 1 0 0 1 1 1 1 Putative papain-like cysteine peptidase (DUF1796) Nop PF01798.13 KEG11015.1 - 8.1e-54 180.9 3.0 4.2e-53 178.6 0.5 2.3 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 KEG11015.1 - 8.2e-27 92.7 0.1 1.6e-26 91.8 0.1 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KEG11015.1 - 1.8e-05 24.7 0.9 0.15 12.2 0.1 2.8 1 1 1 2 2 2 2 NOP5NT (NUC127) domain DUF3306 PF11748.3 KEG11015.1 - 0.085 13.5 0.2 0.085 13.5 0.1 2.4 2 2 0 2 2 2 0 Protein of unknown function (DUF3306) HIRA_B PF09453.5 KEG11016.1 - 0.03 13.8 0.1 0.07 12.7 0.1 1.6 1 0 0 1 1 1 0 HIRA B motif Ribosomal_L27e PF01777.13 KEG11017.1 - 4.9e-26 90.6 2.7 7.3e-26 90.1 1.9 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 KEG11017.1 - 5.6e-08 32.1 0.5 1.3e-07 31.0 0.4 1.6 1 0 0 1 1 1 1 KOW motif Pardaxin PF07425.6 KEG11020.1 - 0.12 11.7 0.2 0.25 10.7 0.1 1.5 1 0 0 1 1 1 0 Pardaxin Ribosomal_L27e PF01777.13 KEG11021.1 - 4.9e-26 90.6 2.7 7.3e-26 90.1 1.9 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 KEG11021.1 - 5.6e-08 32.1 0.5 1.3e-07 31.0 0.4 1.6 1 0 0 1 1 1 1 KOW motif Sod_Fe_C PF02777.13 KEG11023.1 - 1.3e-45 153.5 0.8 1.5e-45 153.3 0.6 1.0 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain GSHPx PF00255.14 KEG11024.1 - 1.2e-26 92.1 0.0 1.4e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 KEG11024.1 - 0.0015 18.1 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KEG11024.1 - 0.0061 16.1 0.0 0.0073 15.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin Sybindin PF04099.7 KEG11025.1 - 1.3e-22 80.0 0.0 1.5e-22 79.8 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 KEG11025.1 - 2.6e-10 40.2 0.0 3e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region ACOX PF01756.14 KEG11025.1 - 0.018 14.4 0.0 0.064 12.6 0.0 1.8 1 1 1 2 2 2 0 Acyl-CoA oxidase Aa_trans PF01490.13 KEG11027.1 - 3.3e-56 190.5 37.9 4e-56 190.2 26.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KEG11027.1 - 4.7e-09 35.5 18.1 4.7e-09 35.5 12.6 2.5 1 1 2 3 3 3 1 Tryptophan/tyrosine permease family OapA_N PF08525.6 KEG11027.1 - 0.052 13.3 0.2 0.25 11.1 0.1 2.2 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif DUF2254 PF10011.4 KEG11027.1 - 0.22 9.9 3.9 0.46 8.8 2.3 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2254) Rhodanese PF00581.15 KEG11028.1 - 1.8e-10 41.1 0.0 2e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain FA_desaturase PF00487.19 KEG11029.1 - 1.8e-25 89.8 23.1 2.4e-25 89.4 16.0 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 KEG11029.1 - 0.0005 19.2 0.0 0.00089 18.4 0.0 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Ferritin PF00210.19 KEG11031.1 - 0.027 14.2 1.1 0.054 13.2 0.8 1.5 1 1 0 1 1 1 0 Ferritin-like domain Snapin_Pallidin PF14712.1 KEG11031.1 - 0.038 14.3 0.8 0.038 14.3 0.6 2.2 2 0 0 2 2 2 0 Snapin/Pallidin DUF461 PF04314.8 KEG11031.1 - 0.049 13.2 0.1 0.14 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF461) FlxA PF14282.1 KEG11031.1 - 0.18 11.7 2.6 0.56 10.1 1.6 2.0 1 1 1 2 2 2 0 FlxA-like protein Med9 PF07544.8 KEG11031.1 - 0.54 10.0 5.3 0.22 11.2 0.6 2.3 1 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Ax_dynein_light PF10211.4 KEG11031.1 - 1.3 8.7 7.0 0.64 9.8 0.2 2.6 3 0 0 3 3 3 0 Axonemal dynein light chain Viral_P18 PF04521.8 KEG11031.1 - 1.7 8.0 4.7 1.7 8.0 0.2 2.9 1 1 2 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein YlqD PF11068.3 KEG11031.1 - 6.8 6.7 8.1 0.23 11.4 0.2 2.3 3 0 0 3 3 3 0 YlqD protein HCaRG PF07258.9 KEG11032.1 - 7.3e-05 22.3 0.0 8.9e-05 22.1 0.0 1.0 1 0 0 1 1 1 1 HCaRG protein LemA PF04011.7 KEG11032.1 - 0.061 12.4 0.0 0.071 12.2 0.0 1.1 1 0 0 1 1 1 0 LemA family DUF1777 PF08648.7 KEG11033.1 - 0.0025 17.5 24.0 0.0025 17.5 16.6 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1777) Sigma70_ner PF04546.8 KEG11033.1 - 0.063 12.8 1.6 0.11 12.0 1.1 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 KEG11033.1 - 0.44 10.0 2.7 0.76 9.2 1.9 1.4 1 0 0 1 1 1 0 Nucleoplasmin Pkinase PF00069.20 KEG11034.1 - 7.6e-59 198.9 0.0 1.2e-58 198.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG11034.1 - 3.1e-39 134.6 0.0 4.8e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PAS PF00989.19 KEG11034.1 - 3.5e-07 30.0 0.0 1.6e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 PAS fold Kinase-like PF14531.1 KEG11034.1 - 0.00021 20.3 0.0 0.1 11.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like 7TM_GPCR_Srh PF10318.4 KEG11034.1 - 0.00031 19.6 0.6 0.00065 18.6 0.4 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh APH PF01636.18 KEG11034.1 - 0.026 14.2 0.0 0.075 12.7 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family PAS_9 PF13426.1 KEG11034.1 - 0.045 14.1 0.0 1.2 9.5 0.0 2.5 2 0 0 2 2 2 0 PAS domain PAS_4 PF08448.5 KEG11034.1 - 0.046 13.7 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 PAS fold Kdo PF06293.9 KEG11034.1 - 0.13 11.3 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIH_assoc PF08454.6 KEG11034.1 - 0.88 9.2 4.4 0.46 10.1 0.3 2.3 2 0 0 2 2 2 0 RyR and IP3R Homology associated Ank_2 PF12796.2 KEG11035.1 - 3.8e-10 39.9 0.0 0.00029 21.1 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KEG11035.1 - 1e-09 38.3 1.8 0.099 12.9 0.0 6.5 6 1 1 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEG11035.1 - 4.5e-09 35.6 0.2 0.084 13.1 0.0 5.1 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 KEG11035.1 - 8.5e-07 29.3 0.4 0.00078 19.8 0.0 4.1 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.25 KEG11035.1 - 1.1e-06 28.1 0.3 1.4 8.8 0.1 4.7 4 0 0 4 4 4 2 Ankyrin repeat Fis1_TPR_C PF14853.1 KEG11036.1 - 0.022 14.6 0.4 4.4 7.2 0.0 3.2 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat BLOC1_2 PF10046.4 KEG11037.1 - 4.7e-20 71.5 0.7 5.7e-20 71.3 0.5 1.1 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Transcrip_act PF04949.8 KEG11037.1 - 0.0092 15.6 0.3 0.012 15.2 0.2 1.2 1 0 0 1 1 1 1 Transcriptional activator Antirestrict PF03230.8 KEG11037.1 - 0.019 14.9 0.2 0.042 13.8 0.0 1.6 2 0 0 2 2 2 0 Antirestriction protein Baculo_PEP_C PF04513.7 KEG11037.1 - 0.092 12.5 0.9 0.33 10.7 0.1 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.6 KEG11037.1 - 0.18 11.7 1.2 0.61 10.0 0.1 2.3 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.7 KEG11037.1 - 0.21 11.8 1.2 0.29 11.4 0.3 1.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Spectrin PF00435.16 KEG11037.1 - 0.23 11.7 4.6 4.3 7.6 0.4 2.3 1 1 1 2 2 2 0 Spectrin repeat DUF4200 PF13863.1 KEG11037.1 - 0.45 10.4 3.6 1 9.3 2.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF4164 PF13747.1 KEG11037.1 - 0.97 9.6 4.5 38 4.5 2.9 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Dpy-30 PF05186.8 KEG11039.1 - 0.012 15.0 0.0 0.017 14.5 0.0 1.3 1 1 0 1 1 1 0 Dpy-30 motif RIIa PF02197.12 KEG11039.1 - 0.13 11.7 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit IQ PF00612.22 KEG11041.1 - 0.0065 16.0 0.8 0.0065 16.0 0.6 1.9 2 0 0 2 2 2 1 IQ calmodulin-binding motif DUF4206 PF13901.1 KEG11044.1 - 1.3e-29 103.2 33.9 6.3e-25 87.9 0.7 5.1 5 1 1 6 6 6 4 Domain of unknown function (DUF4206) FYVE PF01363.16 KEG11046.1 - 9.5e-09 35.0 9.7 1.7e-08 34.2 6.7 1.4 1 0 0 1 1 1 1 FYVE zinc finger CALCOCO1 PF07888.6 KEG11046.1 - 9.2e-06 24.2 35.6 0.00028 19.3 2.9 2.9 1 1 2 3 3 3 3 Calcium binding and coiled-coil domain (CALCOCO1) like GAS PF13851.1 KEG11046.1 - 0.00023 20.4 34.2 0.0021 17.2 5.9 3.5 1 1 2 3 3 3 2 Growth-arrest specific micro-tubule binding Apolipoprotein PF01442.13 KEG11046.1 - 0.00023 20.7 12.2 0.00023 20.7 8.5 3.3 2 1 1 3 3 3 2 Apolipoprotein A1/A4/E domain Fez1 PF06818.10 KEG11046.1 - 0.0011 19.0 39.9 0.076 13.0 10.8 3.8 2 1 1 3 3 3 3 Fez1 CENP-F_leu_zip PF10473.4 KEG11046.1 - 0.0012 18.6 45.4 0.018 14.9 9.2 4.8 1 1 3 4 4 4 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 KEG11046.1 - 0.0017 17.6 11.8 0.24 10.5 0.2 3.3 1 1 3 4 4 4 3 Reovirus sigma C capsid protein PEARLI-4 PF05278.7 KEG11046.1 - 0.0021 17.5 16.4 0.0044 16.4 1.4 3.2 2 1 1 3 3 3 2 Arabidopsis phospholipase-like protein (PEARLI 4) DUF4200 PF13863.1 KEG11046.1 - 0.0044 16.9 5.8 0.0044 16.9 4.1 4.7 1 1 2 4 4 4 1 Domain of unknown function (DUF4200) APG6 PF04111.7 KEG11046.1 - 0.0063 15.5 4.9 0.0063 15.5 3.4 3.3 1 1 2 3 3 3 2 Autophagy protein Apg6 Baculo_PEP_C PF04513.7 KEG11046.1 - 0.012 15.4 2.5 0.012 15.4 1.8 3.8 1 1 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus bZIP_1 PF00170.16 KEG11046.1 - 0.013 15.3 33.7 0.43 10.5 0.4 7.4 4 2 5 9 9 9 0 bZIP transcription factor DUF972 PF06156.8 KEG11046.1 - 0.015 15.5 28.6 0.44 10.9 0.2 5.2 1 1 1 3 3 3 0 Protein of unknown function (DUF972) Myosin_tail_1 PF01576.14 KEG11046.1 - 0.021 12.6 45.8 0.028 12.1 20.0 2.9 1 1 1 2 2 2 0 Myosin tail ATG16 PF08614.6 KEG11046.1 - 0.042 13.6 46.9 0.3 10.8 2.0 4.0 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Bacillus_HBL PF05791.6 KEG11046.1 - 0.12 11.6 9.8 0.16 11.3 0.5 3.3 1 1 2 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) AIP3 PF03915.8 KEG11046.1 - 0.2 10.4 22.0 0.27 10.0 4.4 2.7 1 1 2 3 3 3 0 Actin interacting protein 3 IncA PF04156.9 KEG11046.1 - 0.21 11.1 51.7 0.067 12.7 2.4 3.9 1 1 1 2 2 1 0 IncA protein IBR PF01485.16 KEG11046.1 - 0.23 11.3 13.3 0.19 11.6 6.0 2.3 1 1 1 2 2 2 0 IBR domain TPR_MLP1_2 PF07926.7 KEG11046.1 - 0.44 10.2 38.5 0.62 9.8 9.3 4.3 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Bcr-Abl_Oligo PF09036.5 KEG11046.1 - 0.79 9.7 5.9 0.2 11.6 0.7 2.4 2 1 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain CCDC155 PF14662.1 KEG11046.1 - 1.8 8.1 43.0 0.59 9.6 12.2 4.1 1 1 2 4 4 4 0 Coiled-coil region of CCDC155 zf-B_box PF00643.19 KEG11046.1 - 2.5 8.0 7.2 3.7 7.5 2.0 2.4 2 0 0 2 2 2 0 B-box zinc finger Mnd1 PF03962.10 KEG11046.1 - 2.5 7.7 41.6 0.33 10.5 1.9 4.4 1 1 3 5 5 5 0 Mnd1 family Spc7 PF08317.6 KEG11046.1 - 2.8 6.5 33.0 1.4 7.5 7.5 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein Tweety PF04906.8 KEG11046.1 - 2.9 6.2 8.4 3.2 6.0 0.3 2.6 3 0 0 3 3 3 0 Tweety Spectrin PF00435.16 KEG11046.1 - 3.3 8.0 31.8 2.1 8.6 4.3 4.7 3 2 1 4 4 4 0 Spectrin repeat Atg14 PF10186.4 KEG11046.1 - 4.4 6.1 38.3 2.2 7.1 5.6 3.3 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 COG5 PF10392.4 KEG11046.1 - 5.1 7.0 16.5 0.21 11.5 3.6 3.5 2 1 1 4 4 4 0 Golgi transport complex subunit 5 Nup54 PF13874.1 KEG11046.1 - 6.4 6.4 34.2 0.064 12.9 3.5 3.8 1 1 2 3 3 2 0 Nucleoporin complex subunit 54 DUF342 PF03961.8 KEG11046.1 - 7.7 4.8 30.4 0.39 9.0 0.6 4.0 1 1 3 4 4 4 0 Protein of unknown function (DUF342) Ribosomal_L38e PF01781.13 KEG11048.1 - 1.5e-30 104.7 5.6 1.8e-30 104.5 3.9 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family DUF2359 PF10151.4 KEG11048.1 - 0.063 11.8 0.1 0.063 11.8 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2359) AMP-binding PF00501.23 KEG11050.1 - 5.6e-84 281.9 0.0 7.1e-84 281.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Pkinase PF00069.20 KEG11052.1 - 1.7e-56 191.2 0.0 2.2e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG11052.1 - 3.5e-30 104.9 0.0 4.8e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KEG11052.1 - 2e-05 23.9 0.2 5.7e-05 22.5 0.1 1.5 1 1 0 1 1 1 1 RIO1 family APH PF01636.18 KEG11052.1 - 0.00039 20.2 0.0 0.19 11.4 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KEG11052.1 - 0.001 18.1 0.0 0.0019 17.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family BAF1_ABF1 PF04684.8 KEG11053.1 - 0.0098 14.7 4.9 0.016 14.1 3.4 1.3 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor PsbY PF06298.6 KEG11054.1 - 0.049 13.1 2.6 0.15 11.6 1.8 1.8 1 0 0 1 1 1 0 Photosystem II protein Y (PsbY) DSPc PF00782.15 KEG11055.1 - 1.6e-30 105.4 0.0 2.8e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain LRR_8 PF13855.1 KEG11055.1 - 3.9e-11 42.5 3.5 3.3e-05 23.5 3.0 3.2 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KEG11055.1 - 1.6e-10 40.3 5.0 7.9e-05 22.1 0.3 3.8 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEG11055.1 - 2.3e-07 29.8 3.7 0.31 11.2 0.1 5.1 4 0 0 4 4 4 2 Leucine Rich Repeat Y_phosphatase PF00102.22 KEG11055.1 - 0.00066 19.0 0.0 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase LRR_7 PF13504.1 KEG11055.1 - 0.0017 18.2 1.6 2.5 8.6 0.1 4.6 4 0 0 4 4 4 1 Leucine rich repeat APS_kinase PF01583.15 KEG11055.1 - 0.039 13.5 0.0 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase LRR_5 PF13306.1 KEG11055.1 - 0.062 13.0 0.0 0.51 10.0 0.0 1.9 1 1 0 1 1 1 0 Leucine rich repeats (6 copies) LRR_6 PF13516.1 KEG11055.1 - 6.5 7.1 5.5 11 6.5 0.1 3.7 5 0 0 5 5 5 0 Leucine Rich repeat XRN_N PF03159.13 KEG11057.1 - 0.072 12.4 0.2 0.072 12.4 0.1 1.0 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus RRM_6 PF14259.1 KEG11058.1 - 0.079 12.9 0.1 0.25 11.3 0.0 1.9 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) TATR PF03430.8 KEG11058.1 - 2.8 6.4 4.8 3.3 6.2 3.3 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator MFS_1 PF07690.11 KEG11059.1 - 1.2e-22 80.1 46.0 2.8e-21 75.6 29.7 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily Adeno_E3B PF03376.9 KEG11059.1 - 0.21 11.5 0.1 0.21 11.5 0.1 3.0 4 0 0 4 4 4 0 Adenovirus E3B protein DivIVA PF05103.8 KEG11060.1 - 0.14 12.2 0.4 0.19 11.7 0.3 1.1 1 0 0 1 1 1 0 DivIVA protein Fumble PF03630.9 KEG11061.1 - 1.9e-73 247.2 0.0 3.1e-73 246.5 0.0 1.3 1 0 0 1 1 1 1 Fumble AMP-binding PF00501.23 KEG11061.1 - 4.9e-19 68.0 0.2 8e-19 67.3 0.2 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Exo_endo_phos PF03372.18 KEG11061.1 - 5.9e-13 49.3 0.0 1.1e-12 48.4 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KEG11061.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase PMP22_Claudin PF00822.15 KEG11062.1 - 0.0022 17.6 1.8 0.0055 16.3 0.1 2.0 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family ABC2_membrane PF01061.19 KEG11062.1 - 0.01 15.0 4.7 0.033 13.3 2.3 1.9 1 1 1 2 2 2 0 ABC-2 type transporter EmrE PF13536.1 KEG11062.1 - 0.2 11.8 6.3 0.57 10.3 4.3 1.8 1 1 0 1 1 1 0 Multidrug resistance efflux transporter DUF973 PF06157.6 KEG11062.1 - 0.47 9.3 2.7 9.9 5.0 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF973) BPD_transp_1 PF00528.17 KEG11062.1 - 0.76 9.2 4.7 0.39 10.2 1.6 1.8 1 1 1 2 2 2 0 Binding-protein-dependent transport system inner membrane component MARVEL PF01284.18 KEG11062.1 - 0.83 9.4 8.3 0.35 10.7 2.6 2.2 1 1 1 2 2 2 0 Membrane-associating domain Yip1 PF04893.12 KEG11062.1 - 1.1 8.6 9.5 1.9 7.9 6.6 1.4 1 1 0 1 1 1 0 Yip1 domain RNA_POL_M_15KD PF02150.11 KEG11063.1 - 7.3e-06 25.5 8.2 3.6e-05 23.3 1.9 2.6 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.13 KEG11063.1 - 0.00091 18.8 3.4 0.00091 18.8 2.3 3.2 3 1 0 3 3 3 1 Transcription factor S-II (TFIIS) zf-Sec23_Sec24 PF04810.10 KEG11063.1 - 0.013 15.0 1.9 0.013 15.0 1.3 2.6 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger DUF3133 PF11331.3 KEG11063.1 - 0.11 12.0 1.3 0.18 11.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3133) Zn_Tnp_IS1595 PF12760.2 KEG11063.1 - 0.11 12.2 0.2 0.11 12.2 0.2 2.4 2 1 0 2 2 2 0 Transposase zinc-ribbon domain YhfH PF14149.1 KEG11063.1 - 0.13 12.0 0.6 0.13 12.0 0.4 2.1 2 0 0 2 2 2 0 YhfH-like protein Zn_ribbon_recom PF13408.1 KEG11063.1 - 0.31 11.3 0.2 0.31 11.3 0.1 2.2 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain RRN7 PF11781.3 KEG11063.1 - 0.4 10.2 5.6 13 5.3 0.0 3.7 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 Zn-ribbon_8 PF09723.5 KEG11063.1 - 0.47 10.4 8.8 2.4 8.2 0.5 3.6 4 0 0 4 4 4 0 Zinc ribbon domain HypA PF01155.14 KEG11063.1 - 0.59 9.8 4.7 12 5.6 3.3 2.3 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-C4_Topoisom PF01396.14 KEG11063.1 - 2 7.9 0.0 2 7.9 0.0 3.4 4 0 0 4 4 4 0 Topoisomerase DNA binding C4 zinc finger PyrI_C PF02748.10 KEG11063.1 - 2.3 7.7 6.8 5.6 6.4 0.1 3.1 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-3CxxC PF13695.1 KEG11063.1 - 8.9 6.6 11.2 7.1 6.9 0.1 3.0 2 1 0 2 2 2 0 Zinc-binding domain Proteasome PF00227.21 KEG11064.1 - 3.3e-34 117.8 0.0 3.7e-34 117.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TAA-Trp-ring PF15401.1 KEG11065.1 - 0.065 13.4 0.2 0.36 11.0 0.1 1.9 1 1 1 2 2 2 0 Tryptophan-ring motif of head of Trimeric autotransporter adhesin DUF1700 PF08006.6 KEG11067.1 - 6.8 5.9 7.5 7.8 5.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) Sec10 PF07393.6 KEG11068.1 - 3e-25 88.5 0.2 3.7e-23 81.6 0.0 2.2 2 0 0 2 2 2 2 Exocyst complex component Sec10 BING4CT PF08149.6 KEG11070.1 - 1.4e-31 107.7 0.0 4.9e-31 106.0 0.0 2.0 2 0 0 2 2 2 1 BING4CT (NUC141) domain WD40 PF00400.27 KEG11070.1 - 9.8e-10 37.9 3.0 1.9e-06 27.5 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat Prothymosin PF03247.9 KEG11070.1 - 9.9 6.3 19.1 0.59 10.3 9.5 1.9 2 0 0 2 2 2 0 Prothymosin/parathymosin family Totivirus_coat PF05518.6 KEG11071.1 - 5.4 4.7 8.9 9.3 3.9 6.2 1.3 1 0 0 1 1 1 0 Totivirus coat protein PAT1 PF09770.4 KEG11071.1 - 9.2 4.3 14.2 12 3.9 9.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Meth_synt_2 PF01717.13 KEG11073.1 - 1.4e-151 504.0 0.0 2.1e-143 477.1 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KEG11073.1 - 7.7e-129 429.4 0.0 5e-113 377.4 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain FAM165 PF14981.1 KEG11075.1 - 6.9 6.2 6.3 27 4.3 2.8 2.3 2 0 0 2 2 2 0 FAM165 family DUF3646 PF12362.3 KEG11076.1 - 0.024 14.5 0.6 0.051 13.5 0.0 1.8 2 0 0 2 2 2 0 DNA polymerase III gamma and tau subunits C terminal GreA_GreB_N PF03449.10 KEG11076.1 - 0.056 13.5 0.6 9.3 6.3 0.0 2.5 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal PseudoU_synth_2 PF00849.17 KEG11078.1 - 6.3e-18 65.1 0.0 1.1e-15 57.7 0.0 2.8 1 1 0 1 1 1 1 RNA pseudouridylate synthase zf-C3HC4_3 PF13920.1 KEG11079.1 - 1e-07 31.4 0.1 2e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEG11079.1 - 2.1e-06 27.4 0.2 4.6e-06 26.3 0.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KEG11079.1 - 3.9e-06 26.7 0.4 8.9e-06 25.6 0.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEG11079.1 - 3.1e-05 23.5 0.1 6.6e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEG11079.1 - 5e-05 22.9 0.2 0.00014 21.4 0.1 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KEG11079.1 - 0.0038 17.2 0.1 0.0089 16.1 0.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KEG11079.1 - 0.015 15.0 0.8 1.9 8.2 0.0 2.9 2 0 0 2 2 2 0 RING-type zinc-finger zf-Apc11 PF12861.2 KEG11079.1 - 0.027 14.3 0.1 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 KEG11079.1 - 0.061 12.8 2.0 0.18 11.3 1.4 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.6 KEG11079.1 - 0.16 11.7 0.3 0.42 10.3 0.2 1.6 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4_4 PF15227.1 KEG11079.1 - 0.48 10.3 2.5 0.4 10.6 0.4 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF4200 PF13863.1 KEG11079.1 - 1.7 8.6 7.4 4.6 7.1 2.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) HAUS6_N PF14661.1 KEG11079.1 - 6.3 6.0 7.8 6.4 6.0 2.8 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus BSP_II PF05432.6 KEG11080.1 - 0.0061 15.8 0.9 0.0061 15.8 0.7 3.4 3 0 0 3 3 3 1 Bone sialoprotein II (BSP-II) eIF-3c_N PF05470.7 KEG11080.1 - 0.04 12.0 0.0 0.15 10.1 0.0 1.8 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Spore_coat_CotO PF14153.1 KEG11080.1 - 2 7.8 15.4 0.28 10.6 2.5 2.7 3 0 0 3 3 3 0 Spore coat protein CotO FAM176 PF14851.1 KEG11080.1 - 6.2 6.4 20.1 3.4 7.3 5.0 3.5 4 0 0 4 4 4 0 FAM176 family KaiB PF07689.7 KEG11081.1 - 0.67 9.4 3.5 0.83 9.1 0.6 2.5 3 0 0 3 3 3 0 KaiB domain DnaJ PF00226.26 KEG11082.1 - 5.4e-22 77.3 0.2 9.3e-22 76.5 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ-X PF14308.1 KEG11082.1 - 1.9e-07 30.5 0.2 4.6e-07 29.3 0.1 1.6 2 0 0 2 2 2 1 X-domain of DnaJ-containing NUP50 PF08911.6 KEG11082.1 - 0.027 14.8 1.9 4.1 7.8 1.1 2.8 2 0 0 2 2 2 0 NUP50 (Nucleoporin 50 kDa) Pex19 PF04614.7 KEG11082.1 - 0.063 12.8 0.1 0.15 11.6 0.0 1.6 2 0 0 2 2 2 0 Pex19 protein family LRR_4 PF12799.2 KEG11083.1 - 3.4e-07 29.7 0.0 3.1e-05 23.4 0.0 2.5 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG11083.1 - 1.6e-06 27.7 0.0 0.0028 17.3 0.0 2.3 2 0 0 2 2 2 2 Leucine rich repeat FimP PF09766.4 KEG11083.1 - 0.0032 16.5 3.1 0.0032 16.5 2.1 1.6 2 0 0 2 2 2 1 Fms-interacting protein LRR_1 PF00560.28 KEG11083.1 - 0.0037 17.0 0.2 5 7.5 0.0 3.9 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_7 PF13504.1 KEG11083.1 - 0.11 12.7 0.1 4.7 7.8 0.0 3.1 3 0 0 3 3 3 0 Leucine rich repeat Sporozoite_P67 PF05642.6 KEG11083.1 - 1.9 6.2 10.2 0.039 11.8 2.4 1.5 2 0 0 2 2 2 0 Sporozoite P67 surface antigen zf-HC5HC2H_2 PF13832.1 KEG11085.1 - 1.4e-07 31.4 24.6 1e-06 28.6 10.2 3.1 2 1 0 2 2 2 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KEG11085.1 - 2.3e-05 24.4 12.5 2.3e-05 24.4 8.6 3.2 2 1 1 3 3 3 1 PHD-like zinc-binding domain Rubredoxin PF00301.15 KEG11085.1 - 0.075 12.9 3.5 0.091 12.6 0.4 2.8 3 0 0 3 3 3 0 Rubredoxin Transmemb_17 PF09799.4 KEG11086.1 - 9.6e-22 77.3 4.6 1.3e-21 76.9 3.2 1.2 1 0 0 1 1 1 1 Predicted membrane protein YesK PF14150.1 KEG11086.1 - 0.093 12.8 1.6 0.4 10.8 1.0 2.0 1 1 1 2 2 2 0 YesK-like protein SNARE PF05739.14 KEG11087.1 - 9.3e-05 22.0 0.9 9.3e-05 22.0 0.6 2.4 2 0 0 2 2 2 1 SNARE domain Hypoth_Ymh PF09509.5 KEG11087.1 - 0.014 15.0 2.4 0.16 11.5 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (Hypoth_ymh) Myosin_head PF00063.16 KEG11089.1 - 3.2e-183 610.4 0.0 1.6e-182 608.1 0.0 1.8 1 1 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.1 KEG11089.1 - 0.018 15.1 0.0 0.07 13.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KEG11089.1 - 0.43 11.3 0.0 0.43 11.3 0.0 3.6 3 1 0 3 3 3 0 AAA domain CAF-1_p150 PF11600.3 KEG11089.1 - 1.7 7.9 19.9 3.6 6.9 13.8 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ham1p_like PF01725.11 KEG11092.1 - 8.2e-57 191.6 0.0 9.3e-57 191.4 0.0 1.0 1 0 0 1 1 1 1 Ham1 family DUF2158 PF09926.4 KEG11095.1 - 0.062 12.7 2.6 7.4 6.0 0.1 2.7 1 1 1 2 2 2 0 Uncharacterized small protein (DUF2158) Pyridoxal_deC PF00282.14 KEG11096.1 - 8.3e-29 100.1 0.3 4.2e-27 94.5 0.0 2.7 3 0 0 3 3 3 2 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KEG11096.1 - 0.02 13.6 0.0 0.032 12.9 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V AOX PF01786.12 KEG11098.1 - 0.018 14.4 0.7 0.024 14.0 0.5 1.2 1 0 0 1 1 1 0 Alternative oxidase PRA1 PF03208.14 KEG11098.1 - 0.063 12.6 2.7 0.14 11.4 1.4 1.9 2 1 0 2 2 2 0 PRA1 family protein Tmemb_18A PF09771.4 KEG11098.1 - 0.3 11.0 2.0 0.48 10.3 0.2 2.0 1 1 1 2 2 2 0 Transmembrane protein 188 MIP-T3 PF10243.4 KEG11099.1 - 0.38 9.1 26.9 0.57 8.5 18.6 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DHO_dh PF01180.16 KEG11101.1 - 9.9e-27 93.6 0.0 1.1e-26 93.4 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase PcrB PF01884.12 KEG11101.1 - 0.0049 16.1 0.0 0.0073 15.5 0.0 1.3 1 0 0 1 1 1 1 PcrB family FMN_dh PF01070.13 KEG11101.1 - 0.12 11.1 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase DHO_dh PF01180.16 KEG11102.1 - 1.1e-17 63.9 0.0 1.3e-17 63.7 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase PriCT_1 PF08708.6 KEG11103.1 - 0.34 10.7 1.8 2.2 8.1 0.1 2.6 2 0 0 2 2 2 0 Primase C terminal 1 (PriCT-1) GAS PF13851.1 KEG11105.1 - 0.6 9.2 13.0 0.039 13.1 4.0 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding ATC_hydrolase PF14196.1 KEG11105.1 - 2.2 8.6 14.7 0.14 12.5 3.1 2.5 2 0 0 2 2 2 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase PIN_4 PF13638.1 KEG11106.1 - 3.4e-15 56.2 0.1 7.9e-15 55.1 0.0 1.6 2 0 0 2 2 2 1 PIN domain PIN_4 PF13638.1 KEG11107.1 - 1.7e-19 70.2 0.2 2.2e-19 69.8 0.2 1.2 1 0 0 1 1 1 1 PIN domain Elongin_A PF06881.6 KEG11107.1 - 0.04 14.2 1.3 0.055 13.8 0.1 1.7 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Glutaredoxin PF00462.19 KEG11108.1 - 1.8e-11 43.8 0.1 2.5e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.1 KEG11108.1 - 0.0089 15.8 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain DUF836 PF05768.9 KEG11108.1 - 0.013 15.7 0.0 0.016 15.4 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin PF00085.15 KEG11108.1 - 0.028 14.0 0.0 0.03 13.9 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin ARD PF03079.9 KEG11111.1 - 7.7e-37 126.6 0.0 1.1e-36 126.2 0.0 1.2 1 0 0 1 1 1 1 ARD/ARD' family DUF953 PF06110.6 KEG11111.1 - 3.5e-10 39.3 0.1 6e-10 38.6 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Cupin_2 PF07883.6 KEG11111.1 - 2.8e-05 23.5 0.0 4.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 KEG11111.1 - 0.0022 17.6 0.0 0.0036 16.9 0.0 1.5 1 0 0 1 1 1 1 AraC-like ligand binding domain Pkinase PF00069.20 KEG11112.1 - 1.7e-52 178.1 0.0 1.2e-35 122.9 0.0 3.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEG11112.1 - 5e-33 114.2 0.0 1.5e-32 112.7 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG11112.1 - 0.041 12.8 0.0 0.073 12.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RCC1 PF00415.13 KEG11113.1 - 9e-72 237.1 44.3 3.9e-13 49.3 0.4 12.9 11 2 0 11 11 11 9 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KEG11113.1 - 3.1e-42 141.3 73.5 1.3e-07 31.0 0.4 13.5 14 0 0 14 14 14 10 Regulator of chromosome condensation (RCC1) repeat PapC_C PF13953.1 KEG11113.1 - 0.045 13.3 3.5 11 5.7 0.0 4.6 5 0 0 5 5 5 0 PapC C-terminal domain GAD-like PF08887.6 KEG11113.1 - 0.22 11.6 0.6 39 4.3 0.0 4.1 5 0 0 5 5 5 0 GAD-like domain DUF525 PF04379.9 KEG11114.1 - 7e-23 80.4 0.0 1.3e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF525) RCC1 PF00415.13 KEG11115.1 - 5.2e-60 199.4 33.1 4.8e-12 45.9 0.6 11.3 12 0 0 12 12 12 9 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KEG11115.1 - 3e-48 160.4 63.2 2.3e-07 30.2 0.7 12.2 12 0 0 12 12 12 11 Regulator of chromosome condensation (RCC1) repeat Gp37_Gp68 PF07505.6 KEG11115.1 - 0.059 12.5 0.1 0.098 11.8 0.0 1.2 1 0 0 1 1 1 0 Phage protein Gp37/Gp68 Hira PF07569.6 KEG11115.1 - 0.22 10.7 0.3 10 5.2 0.0 3.5 3 1 0 4 4 4 0 TUP1-like enhancer of split RRM_1 PF00076.17 KEG11116.1 - 3e-11 42.7 0.1 4.5e-11 42.2 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG11116.1 - 7.4e-11 41.8 0.1 1e-10 41.4 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG11116.1 - 1.4e-05 24.8 0.0 2.2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.6 KEG11116.1 - 0.11 12.0 0.0 0.23 10.9 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1866) RRM_6 PF14259.1 KEG11119.1 - 6.5e-10 38.8 0.0 1.1e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEG11119.1 - 9e-10 38.0 0.0 5e-09 35.6 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG11119.1 - 0.0036 17.1 0.0 0.006 16.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mucin PF01456.12 KEG11122.1 - 0.0035 17.1 1.3 0.0035 17.1 0.9 3.7 1 1 1 3 3 3 2 Mucin-like glycoprotein DIOX_N PF14226.1 KEG11122.1 - 0.044 14.3 0.3 0.15 12.6 0.2 2.0 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal LST1 PF05083.8 KEG11122.1 - 3.7 7.6 5.3 12 5.9 0.3 2.8 2 0 0 2 2 2 0 LST-1 protein DUF930 PF06059.7 KEG11123.1 - 0.71 10.1 4.5 0.58 10.4 0.5 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF930) APG6 PF04111.7 KEG11123.1 - 9.4 5.1 12.2 13 4.7 8.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Mucin PF01456.12 KEG11124.1 - 0.0004 20.1 1.3 0.00048 19.9 0.9 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein TROVE PF05731.6 KEG11124.1 - 0.067 11.9 4.6 0.074 11.7 3.2 1.0 1 0 0 1 1 1 0 TROVE domain DUF2124 PF09897.4 KEG11124.1 - 0.075 12.7 0.4 0.097 12.3 0.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2124) DUF2149 PF09919.4 KEG11124.1 - 0.25 11.4 3.0 0.55 10.3 1.5 1.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2149) TraW_N PF12477.3 KEG11124.1 - 1.3 9.0 4.0 0.54 10.2 0.8 1.9 2 0 0 2 2 2 0 Sex factor F TraW protein N terminal Zea_mays_MuDR PF05928.6 KEG11124.1 - 3.9 6.8 10.0 4.9 6.5 6.9 1.2 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) DUF2681 PF10883.3 KEG11124.1 - 8 6.7 7.0 16 5.8 4.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) BtpA PF03437.10 KEG11125.1 - 0.0068 15.6 0.4 0.0083 15.4 0.3 1.0 1 0 0 1 1 1 1 BtpA family XH PF03469.9 KEG11125.1 - 0.012 15.3 0.1 0.015 14.9 0.1 1.2 1 0 0 1 1 1 0 XH domain Mcm10 PF09332.6 KEG11125.1 - 0.018 14.4 1.0 0.021 14.1 0.7 1.0 1 0 0 1 1 1 0 Mcm10 replication factor HR1 PF02185.11 KEG11125.1 - 0.024 14.3 0.1 0.033 13.9 0.1 1.3 1 0 0 1 1 1 0 Hr1 repeat Sec2p PF06428.6 KEG11125.1 - 0.034 14.0 2.2 0.039 13.7 1.0 1.4 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p DMPK_coil PF08826.5 KEG11125.1 - 0.038 13.8 2.7 0.055 13.3 1.9 1.2 1 0 0 1 1 1 0 DMPK coiled coil domain like IFT20 PF14931.1 KEG11125.1 - 0.043 13.7 0.1 0.053 13.4 0.1 1.3 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 Mucin PF01456.12 KEG11126.1 - 1.6 8.4 19.9 12 5.6 13.8 2.1 1 1 0 1 1 1 0 Mucin-like glycoprotein MGC-24 PF05283.6 KEG11126.1 - 6.7 6.4 17.8 4.8 6.9 4.0 2.1 1 1 1 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) Tetraspannin PF00335.15 KEG11128.1 - 9.2e-27 93.7 4.9 5e-26 91.3 4.0 1.7 1 1 0 1 1 1 1 Tetraspanin family SieB PF14163.1 KEG11128.1 - 0.0091 15.5 0.7 0.62 9.6 0.0 2.3 2 0 0 2 2 2 2 Superinfection exclusion protein B Zip PF02535.17 KEG11128.1 - 0.21 10.5 3.3 4.1 6.3 0.0 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter PRRSV_Env PF02340.10 KEG11129.1 - 0.2 10.7 1.8 0.28 10.3 0.7 1.6 1 1 1 2 2 2 0 PRRSV putative envelope protein PRK PF00485.13 KEG11131.1 - 5.3e-07 29.3 0.0 0.0044 16.5 0.0 2.3 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 KEG11131.1 - 7.5e-07 30.0 0.4 4.2e-05 24.3 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KEG11131.1 - 1.1e-05 25.6 0.0 0.0016 18.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KEG11131.1 - 0.02 14.7 0.2 0.091 12.6 0.0 2.3 3 0 0 3 3 3 0 AAA domain CPT PF07931.7 KEG11131.1 - 0.035 13.7 0.0 0.094 12.3 0.0 1.7 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_22 PF13401.1 KEG11131.1 - 0.15 12.2 0.0 0.38 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain TP6A_N PF04406.9 KEG11133.1 - 2.7e-10 39.7 0.1 5.1e-10 38.8 0.1 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase RRM_1 PF00076.17 KEG11134.1 - 3.5e-14 52.1 0.0 6.6e-14 51.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.16 KEG11134.1 - 1.1e-12 48.4 0.0 4e-12 46.6 0.0 1.9 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_6 PF14259.1 KEG11134.1 - 1.8e-08 34.2 0.1 7.6e-08 32.2 0.0 2.2 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG11134.1 - 1.9e-08 33.9 0.1 5.2e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KEG11134.1 - 0.07 12.8 0.1 0.47 10.2 0.0 2.3 2 0 0 2 2 2 0 Limkain b1 zf-rbx1 PF12678.2 KEG11135.1 - 4.6e-17 61.8 13.0 5.7e-17 61.5 9.0 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KEG11135.1 - 2.9e-11 43.0 8.8 3.4e-11 42.8 6.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 KEG11135.1 - 0.00011 21.9 19.2 0.00047 19.9 13.3 2.1 1 1 0 1 1 1 1 Ring finger domain UPF0547 PF10571.4 KEG11135.1 - 0.051 13.2 1.6 0.094 12.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-C3HC4_2 PF13923.1 KEG11135.1 - 0.11 12.5 19.2 6.5 6.8 13.4 2.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEG11135.1 - 0.14 11.8 18.3 1.8 8.2 12.7 2.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEG11135.1 - 0.18 11.5 16.5 1.3 8.7 10.7 2.4 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KEG11135.1 - 0.58 9.8 18.6 15 5.3 12.3 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Defensin_2 PF01097.13 KEG11135.1 - 5.7 6.7 10.0 1.1 9.0 4.0 2.0 2 0 0 2 2 2 0 Arthropod defensin zf-rbx1 PF12678.2 KEG11136.1 - 1.1e-23 83.1 11.4 2.5e-13 49.9 2.3 2.2 2 0 0 2 2 2 2 RING-H2 zinc finger zf-Apc11 PF12861.2 KEG11136.1 - 2.2e-13 49.8 12.9 3.7e-09 36.2 1.8 2.2 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 KEG11136.1 - 1.2e-08 34.6 5.1 1.2e-08 34.6 3.5 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KEG11136.1 - 9.8e-05 21.9 10.2 0.00039 20.0 1.9 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEG11136.1 - 0.00027 20.8 5.4 0.00027 20.8 3.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEG11136.1 - 0.001 18.7 3.4 0.001 18.7 2.4 2.5 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KEG11136.1 - 0.0043 16.6 4.4 0.0043 16.6 3.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF4206 PF13901.1 KEG11136.1 - 0.027 14.0 5.6 1.3 8.5 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4206) DiS_P_DiS PF06750.8 KEG11136.1 - 0.39 10.5 4.0 1.1 9.1 0.2 2.2 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain Baculo_RING PF05883.6 KEG11136.1 - 3.2 7.5 5.5 2.1 8.2 0.1 2.4 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain Cas_CXXC_CXXC PF09706.5 KEG11136.1 - 6.7 6.9 7.8 1.1e+02 3.0 0.0 3.1 2 1 1 3 3 3 0 CRISPR-associated protein (Cas_CXXC_CXXC) zf-RING_UBOX PF13445.1 KEG11136.1 - 9 6.1 11.1 3.6 7.3 2.5 2.8 2 1 0 2 2 2 0 RING-type zinc-finger Mito_carr PF00153.22 KEG11137.1 - 4.3e-49 164.1 6.0 6e-19 67.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Kinesin PF00225.18 KEG11138.1 - 4.4e-88 295.1 0.1 6.5e-88 294.6 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain Bac_DnaA PF00308.13 KEG11138.1 - 0.2 11.2 2.7 0.42 10.2 0.1 2.1 2 0 0 2 2 2 0 Bacterial dnaA protein Peptidase_C97 PF05903.9 KEG11140.1 - 2.7e-26 92.1 0.2 4.8e-26 91.3 0.1 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 KEG11140.1 - 0.0013 18.6 0.0 0.0038 17.1 0.0 1.7 1 0 0 1 1 1 1 Lecithin retinol acyltransferase Vasohibin PF14822.1 KEG11140.1 - 0.21 10.6 0.1 0.53 9.3 0.0 1.6 2 0 0 2 2 2 0 Vasohibin Pkinase PF00069.20 KEG11142.1 - 4.3e-46 157.1 0.0 3.8e-40 137.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEG11142.1 - 1.2e-17 63.9 0.0 6.7e-16 58.1 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG11142.1 - 1.6e-05 23.9 0.0 0.0014 17.6 0.0 2.7 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 KEG11142.1 - 0.00022 20.3 0.0 0.0004 19.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Daxx PF03344.10 KEG11142.1 - 0.0035 15.9 2.5 0.0035 15.9 1.8 1.5 2 0 0 2 2 2 1 Daxx Family YrbL-PhoP_reg PF10707.4 KEG11142.1 - 0.024 13.9 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 KEG11142.1 - 0.038 13.7 0.0 5.6 6.6 0.0 2.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Tim54 PF11711.3 KEG11142.1 - 0.054 12.0 0.0 0.082 11.4 0.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Nop14 PF04147.7 KEG11142.1 - 0.083 10.8 7.1 0.12 10.3 4.9 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KEG11142.1 - 0.36 8.7 1.7 0.54 8.2 1.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2890 PF11081.3 KEG11142.1 - 1.3 8.9 11.2 2.9 7.9 7.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) TRAP_alpha PF03896.11 KEG11142.1 - 2.8 6.8 5.4 4.5 6.1 3.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sugar_tr PF00083.19 KEG11143.1 - 5.5e-115 384.4 29.5 6.3e-115 384.3 20.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEG11143.1 - 1.2e-33 116.3 31.3 1.2e-33 116.3 21.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Kelch_5 PF13854.1 KEG11144.1 - 1.3e-18 66.4 0.4 3.1e-05 23.8 0.0 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_4 PF13418.1 KEG11144.1 - 9.7e-18 63.6 11.1 1.7e-06 27.6 0.0 4.9 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.1 KEG11144.1 - 1.3e-17 63.3 22.0 6.1e-06 26.2 0.0 6.3 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.1 KEG11144.1 - 3.4e-09 36.4 0.1 0.017 15.2 0.0 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 KEG11144.1 - 7e-09 35.1 3.4 0.033 13.9 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 KEG11144.1 - 1.4e-07 30.9 4.5 0.14 11.7 0.0 4.7 5 0 0 5 5 5 3 Kelch motif RAG2 PF03089.9 KEG11144.1 - 0.038 12.7 2.7 3.9 6.1 0.1 3.2 2 2 1 4 4 4 0 Recombination activating protein 2 ComC PF03047.9 KEG11145.1 - 0.024 14.0 1.4 0.024 14.0 1.0 1.6 2 0 0 2 2 2 0 COMC family L_biotic_typeA PF04604.8 KEG11145.1 - 0.045 13.4 0.7 0.098 12.3 0.1 1.8 2 0 0 2 2 2 0 Type-A lantibiotic DUF1935 PF09149.5 KEG11146.1 - 7.2e-33 112.6 0.0 1.3e-32 111.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) META PF03724.11 KEG11146.1 - 4.5e-23 81.0 4.9 3.7e-08 33.1 0.0 3.3 3 0 0 3 3 3 3 META domain Asp23 PF03780.8 KEG11146.1 - 0.027 14.7 0.0 0.094 13.0 0.0 1.9 1 0 0 1 1 1 0 Asp23 family Pab87_oct PF13969.1 KEG11146.1 - 0.081 13.0 0.2 5 7.2 0.0 3.3 3 0 0 3 3 3 0 Pab87 octamerisation domain META PF03724.11 KEG11147.1 - 3.3e-12 46.1 0.0 4.1e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 META domain LRR_6 PF13516.1 KEG11148.1 - 6.8e-18 62.6 7.3 0.00088 19.0 0.0 7.4 7 0 0 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.2 KEG11148.1 - 3.6e-11 42.4 14.5 0.00044 19.8 0.0 4.9 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG11148.1 - 8e-08 31.9 13.0 0.0055 16.4 0.3 5.0 3 1 1 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 KEG11148.1 - 7e-07 28.4 12.1 2.1 8.7 0.1 7.2 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_7 PF13504.1 KEG11148.1 - 9.7e-06 24.9 12.6 2.4 8.7 0.0 7.5 8 0 0 8 8 8 2 Leucine rich repeat Acyltransferase PF01553.16 KEG11149.1 - 1.4e-15 56.8 0.0 2.6e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Sec63 PF02889.11 KEG11150.1 - 3.5e-78 262.9 0.0 1.5e-70 237.9 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 KEG11150.1 - 4e-35 120.7 0.1 1e-27 96.6 0.2 2.8 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KEG11150.1 - 4.4e-08 32.8 0.0 1.1e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEG11150.1 - 8.4e-07 29.0 0.0 2.1e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KEG11150.1 - 0.0032 17.5 0.1 0.061 13.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain Mpp10 PF04006.7 KEG11150.1 - 0.092 11.0 2.6 0.34 9.2 1.3 1.9 2 0 0 2 2 2 0 Mpp10 protein UBA PF00627.26 KEG11151.1 - 0.42 10.5 2.7 8 6.4 0.0 3.0 3 0 0 3 3 3 0 UBA/TS-N domain FH2 PF02181.18 KEG11152.1 - 5.1e-49 167.1 0.0 6.8e-49 166.6 0.0 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain Med9 PF07544.8 KEG11152.1 - 0.054 13.2 0.6 0.28 10.9 0.0 2.6 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF4507 PF14964.1 KEG11152.1 - 0.11 11.2 0.0 0.19 10.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4507) Pox_A_type_inc PF04508.7 KEG11152.1 - 0.2 11.5 1.9 6.7 6.7 0.1 2.7 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF1712 PF08217.6 KEG11153.1 - 8.8e-07 27.5 0.0 1.1e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) Telomerase_RBD PF12009.3 KEG11154.1 - 4.2e-29 101.1 3.4 9.1e-29 100.1 2.3 1.5 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 KEG11154.1 - 0.015 14.6 0.0 0.037 13.3 0.0 1.6 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_13 PF13166.1 KEG11155.1 - 0.019 13.4 4.4 0.042 12.3 3.0 1.5 1 1 0 1 1 1 0 AAA domain OmpH PF03938.9 KEG11155.1 - 0.029 14.3 10.9 0.81 9.6 0.0 2.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Fez1 PF06818.10 KEG11155.1 - 0.13 12.2 13.8 0.12 12.3 8.1 2.0 1 1 0 2 2 2 0 Fez1 Mnd1 PF03962.10 KEG11155.1 - 0.15 11.6 9.9 0.2 11.2 4.6 2.5 1 1 1 2 2 2 0 Mnd1 family Cob_adeno_trans PF01923.13 KEG11155.1 - 0.37 10.5 5.1 0.32 10.7 0.8 2.4 1 1 1 2 2 2 0 Cobalamin adenosyltransferase HrpB7 PF09486.5 KEG11155.1 - 0.38 10.6 9.5 0.28 11.1 2.8 2.8 1 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Spc7 PF08317.6 KEG11155.1 - 0.43 9.1 11.8 0.39 9.3 4.4 2.2 1 1 2 3 3 3 0 Spc7 kinetochore protein Bacillus_HBL PF05791.6 KEG11155.1 - 0.68 9.2 5.7 0.61 9.4 2.4 2.0 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) APG6 PF04111.7 KEG11155.1 - 0.68 8.9 9.0 0.59 9.1 4.4 1.9 2 0 0 2 2 2 0 Autophagy protein Apg6 COG2 PF06148.6 KEG11155.1 - 0.84 9.5 8.4 5.4 6.8 1.8 2.6 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Macoilin PF09726.4 KEG11155.1 - 1.2 7.2 31.3 1.7 6.8 20.9 1.7 1 1 0 1 1 1 0 Transmembrane protein TPR_MLP1_2 PF07926.7 KEG11155.1 - 2.5 7.8 12.7 1.8 8.3 4.7 2.8 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.4 KEG11155.1 - 5.8 5.7 20.4 0.0075 15.2 5.7 2.2 2 1 1 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 CDC37_N PF03234.9 KEG11155.1 - 6.1 7.1 9.7 4.6 7.5 5.4 1.8 2 0 0 2 2 1 0 Cdc37 N terminal kinase binding Glyco_trans_1_4 PF13692.1 KEG11157.1 - 4.7e-13 49.4 0.0 1.7e-12 47.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KEG11157.1 - 2.2e-12 47.3 0.2 1.4e-11 44.8 0.0 2.4 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.15 KEG11157.1 - 4.5e-11 42.4 0.0 7.6e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KEG11157.1 - 6.2e-09 35.8 2.6 1e-07 31.8 1.8 2.6 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.1 KEG11157.1 - 0.00077 19.6 0.0 0.0017 18.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 KEG11157.1 - 0.085 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Starch synthase catalytic domain CDC45 PF02724.9 KEG11158.1 - 1.3 6.9 11.0 2.5 6.0 7.7 1.4 1 0 0 1 1 1 0 CDC45-like protein TPPK_C PF12555.3 KEG11159.1 - 4e-05 23.2 0.5 5.9e-05 22.7 0.4 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphokinase C terminal SdpI PF13630.1 KEG11159.1 - 0.0038 16.8 0.0 0.005 16.5 0.0 1.1 1 0 0 1 1 1 1 SdpI/YhfL protein family DUF3999 PF13163.1 KEG11159.1 - 0.016 14.2 0.1 0.017 14.0 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3999) DUF4337 PF14235.1 KEG11159.1 - 0.022 14.6 0.0 0.028 14.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF3899 PF13038.1 KEG11159.1 - 0.031 14.4 0.0 0.041 14.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) DUF3649 PF12365.3 KEG11159.1 - 5.9 6.5 7.9 1.2 8.7 2.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3649) CDC73 PF05179.9 KEG11160.1 - 3.4e-29 102.0 0.0 4.6e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family DUF3253 PF11625.3 KEG11161.1 - 0.67 9.8 3.0 0.43 10.5 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3253) Kinesin PF00225.18 KEG11166.1 - 2.9e-81 272.7 0.0 6.8e-49 166.3 0.0 2.5 2 1 0 2 2 2 2 Kinesin motor domain LRR_4 PF12799.2 KEG11167.1 - 0.00027 20.4 1.3 0.0008 18.9 0.9 1.8 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KEG11167.1 - 0.00097 18.9 3.6 0.71 10.1 0.0 3.0 2 0 0 2 2 2 2 Leucine Rich repeat LRR_1 PF00560.28 KEG11167.1 - 0.0028 17.4 3.2 1.4 9.2 0.5 3.0 2 0 0 2 2 2 2 Leucine Rich Repeat LRR_7 PF13504.1 KEG11167.1 - 0.028 14.5 1.6 4.1 8.0 0.0 3.2 2 0 0 2 2 2 0 Leucine rich repeat LRR_8 PF13855.1 KEG11167.1 - 1.7 8.4 4.8 4.2 7.1 2.2 2.3 1 1 1 2 2 2 0 Leucine rich repeat Guanylate_cyc PF00211.15 KEG11168.1 - 3.4e-05 23.2 0.0 6.4e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.15 KEG11169.1 - 2.1e-33 115.2 0.0 3.5e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Peripla_BP_6 PF13458.1 KEG11169.1 - 2.9e-07 30.1 2.7 3.6e-07 29.8 0.9 1.8 2 0 0 2 2 2 1 Periplasmic binding protein Shisa PF13908.1 KEG11169.1 - 0.028 14.5 0.2 0.052 13.7 0.2 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator LRR_4 PF12799.2 KEG11170.1 - 3.5e-26 90.3 22.6 0.00012 21.5 0.2 10.8 9 2 3 12 12 12 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG11170.1 - 2.1e-12 46.5 23.9 0.01 15.5 0.2 8.3 7 3 2 10 10 10 6 Leucine rich repeat LRR_1 PF00560.28 KEG11170.1 - 2.6e-06 26.6 22.6 0.43 10.8 0.2 10.5 12 3 1 13 13 13 3 Leucine Rich Repeat LRR_6 PF13516.1 KEG11170.1 - 7.2e-06 25.5 20.1 6.6 7.1 0.5 11.9 11 3 1 13 13 13 1 Leucine Rich repeat LRR_7 PF13504.1 KEG11170.1 - 0.049 13.8 33.7 0.29 11.5 0.8 12.5 14 1 0 14 14 14 0 Leucine rich repeat LRR_2 PF07723.8 KEG11170.1 - 0.19 12.2 13.3 4.3 7.9 0.0 8.1 10 0 0 10 10 10 0 Leucine Rich Repeat SHIPPO-rpt PF07004.7 KEG11172.1 - 5.6e-59 194.2 211.0 0.027 15.3 0.1 42.1 42 0 0 42 42 42 35 Sperm-tail PG-rich repeat ABC-3 PF00950.12 KEG11173.1 - 0.043 13.0 0.1 0.043 13.0 0.0 1.7 2 0 0 2 2 2 0 ABC 3 transport family Mg_trans_NIPA PF05653.9 KEG11173.1 - 0.33 9.8 2.6 0.2 10.5 0.2 1.6 2 0 0 2 2 2 0 Magnesium transporter NIPA DUF4139 PF13598.1 KEG11174.1 - 1.5e-69 234.7 2.8 1.8e-69 234.4 1.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4384 PF14326.1 KEG11174.1 - 0.13 12.0 0.1 0.47 10.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4384) DUF3437 PF11919.3 KEG11175.1 - 5.3e-21 74.1 0.0 1.7e-20 72.5 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) PRD_Mga PF08270.6 KEG11175.1 - 0.077 12.2 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) PRD domain FtsK_SpoIIIE PF01580.13 KEG11176.1 - 0.0096 15.4 0.1 0.015 14.7 0.1 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 KEG11176.1 - 0.011 15.7 0.1 0.017 15.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.5 KEG11176.1 - 0.026 13.7 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NTPase_1 PF03266.10 KEG11176.1 - 0.086 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_14 PF13173.1 KEG11176.1 - 0.14 12.0 0.0 0.41 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Nucleoplasmin PF03066.10 KEG11180.1 - 2.1e-08 33.7 0.3 2.1e-08 33.7 0.2 4.1 1 1 3 4 4 4 1 Nucleoplasmin CENP-T PF15511.1 KEG11180.1 - 0.14 11.3 32.5 0.19 10.9 22.5 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T 2-oxoacid_dh PF00198.18 KEG11181.1 - 4e-81 271.6 0.0 5e-81 271.3 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KEG11181.1 - 4.3e-21 74.3 1.7 7.4e-21 73.5 1.2 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 KEG11181.1 - 6.2e-07 28.9 0.9 0.023 14.3 0.1 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like GCV_H PF01597.14 KEG11181.1 - 0.00016 21.3 0.2 0.00029 20.4 0.2 1.4 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD PF00529.15 KEG11181.1 - 0.0041 16.4 0.6 0.086 12.1 0.2 2.1 1 1 1 2 2 2 1 HlyD family secretion protein HlyD_3 PF13437.1 KEG11181.1 - 0.01 16.1 0.8 0.043 14.1 0.2 2.1 1 1 1 2 2 2 0 HlyD family secretion protein HlyD_2 PF12700.2 KEG11181.1 - 0.023 13.8 0.6 2.6 7.1 0.0 2.5 2 1 1 3 3 3 0 HlyD family secretion protein PAT1 PF09770.4 KEG11181.1 - 0.34 9.1 3.1 0.37 8.9 2.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Rft-1 PF04506.8 KEG11182.1 - 3.1e-32 111.6 3.4 2.2e-30 105.5 2.3 2.1 1 1 0 1 1 1 1 Rft protein GCD14 PF08704.5 KEG11183.1 - 8.7e-68 228.4 0.2 8.2e-42 143.4 0.0 3.0 2 1 1 3 3 3 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 KEG11183.1 - 9.4e-10 38.2 0.0 4.2e-09 36.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEG11183.1 - 4.6e-05 23.4 0.1 0.00012 22.0 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KEG11183.1 - 9.3e-05 22.0 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.7 KEG11183.1 - 0.00059 20.2 0.0 0.018 15.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEG11183.1 - 0.0014 19.1 0.0 0.0031 18.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEG11183.1 - 0.0042 17.5 0.0 0.088 13.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEG11183.1 - 0.0078 15.6 0.0 0.019 14.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Fibrillarin PF01269.12 KEG11183.1 - 0.013 14.3 0.0 2.9 6.7 0.0 2.2 2 0 0 2 2 2 0 Fibrillarin Methyltransf_24 PF13578.1 KEG11183.1 - 0.03 15.1 0.0 0.076 13.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 KEG11183.1 - 0.084 11.9 0.0 0.93 8.5 0.0 2.0 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family WW PF00397.21 KEG11184.1 - 1.5e-06 27.9 1.4 3.7e-06 26.6 1.0 1.7 1 0 0 1 1 1 1 WW domain MCM PF00493.18 KEG11185.1 - 1.8e-120 401.7 1.0 2.9e-120 401.0 0.7 1.4 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KEG11185.1 - 1.4e-08 35.2 0.0 5.9e-08 33.2 0.0 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KEG11185.1 - 1.1e-07 31.2 0.0 4.7e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KEG11185.1 - 0.0073 16.0 0.0 0.028 14.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KEG11185.1 - 0.015 14.8 0.0 0.035 13.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PIH1 PF08190.7 KEG11185.1 - 0.016 14.7 2.0 0.027 13.9 1.4 1.3 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Sigma54_activat PF00158.21 KEG11185.1 - 0.018 14.4 0.0 0.043 13.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF3441 PF11923.3 KEG11189.1 - 0.068 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3441) Beach PF02138.13 KEG11190.1 - 1.2e-94 316.7 0.0 2.5e-94 315.7 0.0 1.6 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 KEG11190.1 - 0.016 15.0 0.1 0.044 13.6 0.1 1.7 1 0 0 1 1 1 0 PH domain associated with Beige/BEACH NTP_transferase PF00483.18 KEG11191.1 - 6.5e-46 156.6 0.0 7.8e-46 156.3 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 KEG11191.1 - 1.2e-13 51.4 0.0 1.7e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.19 KEG11191.1 - 6e-11 41.3 14.1 1.8e-08 33.4 1.9 3.8 2 1 2 4 4 4 2 Bacterial transferase hexapeptide (six repeats) CTP_transf_3 PF02348.14 KEG11191.1 - 0.00022 20.9 0.0 0.00032 20.4 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase Hexapep_2 PF14602.1 KEG11191.1 - 0.02 14.4 3.9 0.02 14.4 2.7 2.9 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase Methyltransf_16 PF10294.4 KEG11192.1 - 1.4e-15 57.1 0.0 2e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KEG11192.1 - 0.0011 19.4 0.0 0.0023 18.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEG11192.1 - 0.0015 18.1 0.0 0.0023 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEG11192.1 - 0.0033 17.4 0.0 0.0057 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEG11192.1 - 0.0038 16.6 0.1 0.0064 15.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 KEG11192.1 - 0.017 15.5 0.0 0.031 14.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MethyltransfD12 PF02086.10 KEG11192.1 - 0.049 13.0 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase PCMT PF01135.14 KEG11192.1 - 0.06 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 KEG11192.1 - 0.15 11.7 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Tropomyosin_1 PF12718.2 KEG11194.1 - 0.00019 21.2 8.8 0.00019 21.2 6.1 4.7 3 2 1 4 4 4 2 Tropomyosin like Alkyl_sulf_C PF14864.1 KEG11194.1 - 0.16 11.9 0.1 0.16 11.9 0.0 2.9 3 0 0 3 3 3 0 Alkyl sulfatase C-terminal Arginase PF00491.16 KEG11195.1 - 2.6e-35 122.0 0.0 3.1e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Arginase family Bys1 PF04681.7 KEG11196.1 - 0.062 13.0 0.0 0.092 12.4 0.0 1.2 1 0 0 1 1 1 0 Blastomyces yeast-phase-specific protein Snf7 PF03357.16 KEG11196.1 - 0.3 10.4 2.2 0.45 9.8 1.5 1.3 1 0 0 1 1 1 0 Snf7 Pro_isomerase PF00160.16 KEG11197.1 - 4.1e-46 157.0 0.1 5.9e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD AhpC-TSA PF00578.16 KEG11198.1 - 1.8e-38 131.0 0.0 2.4e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KEG11198.1 - 1.4e-14 53.9 0.0 2e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 KEG11198.1 - 1.5e-10 40.5 0.9 2.1e-10 40.0 0.1 1.7 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin OKR_DC_1_C PF03711.10 KEG11198.1 - 0.048 13.7 0.0 0.081 12.9 0.0 1.4 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, C-terminal domain UTP15_C PF09384.5 KEG11199.1 - 4.3e-35 120.5 1.3 4.3e-35 120.5 0.9 1.7 2 0 0 2 2 2 1 UTP15 C terminal WD40 PF00400.27 KEG11199.1 - 4.6e-21 73.8 1.3 6.4e-05 22.6 0.1 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat CPSF_A PF03178.10 KEG11199.1 - 2.9e-07 29.8 0.0 4.2e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 CPSF A subunit region Lgl_C PF08596.5 KEG11199.1 - 0.031 12.7 0.1 0.062 11.7 0.0 1.5 2 0 0 2 2 2 0 Lethal giant larvae(Lgl) like, C-terminal RRM_6 PF14259.1 KEG11201.1 - 8.9e-05 22.4 0.1 0.00067 19.5 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEG11201.1 - 0.0027 17.3 0.0 0.088 12.4 0.0 3.0 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 KEG11202.1 - 0.001 18.8 19.7 0.047 13.6 2.2 3.6 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_4 PF14392.1 KEG11202.1 - 2 8.1 17.4 0.28 10.8 0.2 3.3 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_3 PF13917.1 KEG11202.1 - 4.4 7.1 26.5 0.2 11.4 0.6 4.9 4 0 0 4 4 4 0 Zinc knuckle Cyt-b5 PF00173.23 KEG11203.1 - 6.2e-20 70.7 0.1 8.7e-20 70.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Nucleoside_tran PF01733.13 KEG11204.1 - 2.7e-30 105.5 4.4 4.8e-30 104.7 3.1 1.3 1 0 0 1 1 1 1 Nucleoside transporter NdhL PF10716.4 KEG11204.1 - 0.32 10.7 4.5 2.7 7.8 1.2 2.9 2 0 0 2 2 2 0 NADH dehydrogenase transmembrane subunit TruB_N PF01509.13 KEG11206.1 - 0.039 14.1 0.0 0.39 10.8 0.0 2.5 3 0 0 3 3 3 0 TruB family pseudouridylate synthase (N terminal domain) Flagellar_rod PF05149.7 KEG11209.1 - 5.2e-109 363.8 26.2 9.9e-109 362.9 18.2 1.5 1 0 0 1 1 1 1 Paraflagellar rod protein SH3_9 PF14604.1 KEG11209.1 - 2e-12 46.5 0.0 4.5e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KEG11209.1 - 1.3e-11 43.6 0.0 2.5e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KEG11209.1 - 1.3e-07 30.9 0.0 2.9e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DSPc PF00782.15 KEG11211.1 - 2.4e-26 91.8 0.0 3.9e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KEG11211.1 - 0.0012 18.2 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase MMR_HSR1 PF01926.18 KEG11212.1 - 3.5e-19 68.8 0.0 4.1e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KEG11212.1 - 3.2e-08 32.9 0.0 4.2e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_17 PF13207.1 KEG11212.1 - 0.0061 17.3 0.0 0.0072 17.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 KEG11212.1 - 0.018 14.2 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ArgK PF03308.11 KEG11212.1 - 0.037 12.8 0.0 0.045 12.5 0.0 1.2 1 0 0 1 1 1 0 ArgK protein AAA_10 PF12846.2 KEG11212.1 - 0.04 13.3 0.0 0.048 13.0 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain ABC_tran PF00005.22 KEG11212.1 - 0.1 12.8 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 ABC transporter YchF-GTPase_C PF06071.8 KEG11213.1 - 4.5e-17 61.6 0.0 7.3e-17 60.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF933) TGS PF02824.16 KEG11213.1 - 0.0017 18.1 0.0 0.0044 16.8 0.0 1.6 1 1 0 1 1 1 1 TGS domain SecA_PP_bind PF01043.15 KEG11213.1 - 0.031 14.6 0.0 0.063 13.6 0.0 1.6 1 0 0 1 1 1 0 SecA preprotein cross-linking domain Secretin PF00263.16 KEG11213.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial type II and III secretion system protein CENP-F_leu_zip PF10473.4 KEG11214.1 - 0.00029 20.7 8.2 0.00029 20.7 5.7 5.5 2 1 2 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4250 PF14056.1 KEG11214.1 - 0.003 17.2 0.4 0.003 17.2 0.3 4.2 5 0 0 5 5 5 1 Domain of unknown function (DUF4250) IKKbetaNEMObind PF12179.3 KEG11214.1 - 0.13 12.1 3.8 0.25 11.1 0.6 3.3 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain zf-C4pol PF14260.1 KEG11214.1 - 9.5 6.3 6.4 8.3 6.4 0.6 3.7 3 0 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta Tropomyosin_1 PF12718.2 KEG11215.1 - 1.6e-05 24.7 9.3 1.6e-05 24.7 6.5 3.8 3 1 0 4 4 4 1 Tropomyosin like TMF_TATA_bd PF12325.3 KEG11215.1 - 0.0005 19.8 8.5 0.0005 19.8 5.9 3.5 2 1 1 3 3 3 1 TATA element modulatory factor 1 TATA binding Tropomyosin PF00261.15 KEG11215.1 - 0.00088 18.4 10.5 0.00088 18.4 7.3 2.8 3 0 0 3 3 3 1 Tropomyosin DUF641 PF04859.7 KEG11215.1 - 0.0054 16.4 2.6 0.0054 16.4 1.8 3.7 1 1 1 3 3 3 1 Plant protein of unknown function (DUF641) ATG16 PF08614.6 KEG11215.1 - 0.0056 16.5 17.0 0.0056 16.5 11.8 4.1 1 1 3 4 4 4 1 Autophagy protein 16 (ATG16) Mnd1 PF03962.10 KEG11215.1 - 0.0066 16.1 10.0 0.0066 16.1 7.0 3.5 2 2 1 4 4 4 1 Mnd1 family Med9 PF07544.8 KEG11215.1 - 0.0085 15.8 2.2 0.0085 15.8 1.6 4.6 4 1 0 4 4 4 1 RNA polymerase II transcription mediator complex subunit 9 Reo_sigmaC PF04582.7 KEG11215.1 - 0.0098 15.0 7.7 0.14 11.3 1.5 2.2 2 0 0 2 2 2 2 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 KEG11215.1 - 0.013 15.4 41.2 0.15 11.9 6.5 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.7 KEG11215.1 - 0.017 14.8 4.9 0.017 14.8 3.4 3.3 2 1 1 3 3 3 0 Laminin Domain II DUF869 PF05911.6 KEG11215.1 - 0.053 11.7 32.4 0.059 11.5 5.2 2.5 1 1 0 2 2 2 0 Plant protein of unknown function (DUF869) Filament PF00038.16 KEG11215.1 - 0.079 12.4 37.9 0.37 10.2 10.9 3.3 2 1 1 3 3 3 0 Intermediate filament protein Bap31 PF05529.7 KEG11215.1 - 0.27 10.6 14.4 0.13 11.6 0.6 2.7 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Spc7 PF08317.6 KEG11215.1 - 0.3 9.7 33.3 0.43 9.1 10.2 2.8 1 1 2 3 3 3 0 Spc7 kinetochore protein FlgN PF05130.7 KEG11215.1 - 0.53 10.5 39.7 0.032 14.4 11.3 3.0 2 1 1 3 3 3 0 FlgN protein IncA PF04156.9 KEG11215.1 - 0.54 9.8 49.1 1.1 8.8 13.4 2.7 2 1 0 2 2 2 0 IncA protein Baculo_PEP_C PF04513.7 KEG11215.1 - 0.65 9.8 15.7 0.58 9.9 2.0 2.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.1 KEG11215.1 - 1.1 7.6 22.4 0.35 9.2 5.0 1.9 1 1 1 2 2 2 0 AAA domain Phage_GP20 PF06810.6 KEG11215.1 - 1.4 8.3 20.4 0.21 11.0 2.6 3.3 2 1 1 3 3 3 0 Phage minor structural protein GP20 TPR_MLP1_2 PF07926.7 KEG11215.1 - 1.7 8.4 40.6 3.5 7.3 7.8 3.9 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein DUF948 PF06103.6 KEG11215.1 - 1.7 8.5 8.6 7.6 6.4 0.3 3.8 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) TBPIP PF07106.8 KEG11215.1 - 2.3 7.7 28.1 2.8 7.4 3.6 3.4 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF148 PF02520.12 KEG11215.1 - 3 7.6 13.2 0.15 11.8 1.5 3.0 3 1 0 3 3 3 0 Domain of unknown function DUF148 DUF3573 PF12097.3 KEG11215.1 - 3 6.3 5.2 0.99 7.9 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) DUF2120 PF09893.4 KEG11215.1 - 3.1 7.7 5.7 0.99 9.3 0.4 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) HemX PF04375.9 KEG11215.1 - 3.7 6.0 33.5 0.021 13.4 7.0 3.3 1 1 2 3 3 3 0 HemX DUF677 PF05055.7 KEG11215.1 - 4 6.0 10.3 6.9 5.2 0.5 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF677) CorA PF01544.13 KEG11215.1 - 4.4 6.2 20.7 0.1 11.6 1.5 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein IFT57 PF10498.4 KEG11215.1 - 4.5 5.9 27.2 0.57 8.8 4.4 2.5 2 1 0 2 2 2 0 Intra-flagellar transport protein 57 NAP PF00956.13 KEG11215.1 - 5.7 5.9 15.5 0.028 13.5 2.7 2.3 2 1 0 2 2 2 0 Nucleosome assembly protein (NAP) NPV_P10 PF05531.7 KEG11215.1 - 6.1 7.1 10.5 7.1 6.9 1.5 3.5 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Sec34 PF04136.10 KEG11215.1 - 6.1 6.5 10.9 3.3 7.3 1.8 2.3 2 0 0 2 2 2 0 Sec34-like family DUF724 PF05266.9 KEG11215.1 - 7.1 6.2 28.9 1.3 8.6 2.9 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF724) YPEB PF14620.1 KEG11215.1 - 7.8 5.4 19.8 5 6.0 5.1 2.8 1 1 1 3 3 3 0 YpeB sporulation PEPCK_ATP PF01293.15 KEG11216.1 - 1.1e-194 647.3 0.0 1.2e-194 647.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.1 KEG11216.1 - 0.036 13.9 0.0 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KEG11216.1 - 0.15 12.0 0.0 0.38 10.6 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_13 PF13166.1 KEG11216.1 - 0.22 9.9 0.0 0.32 9.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain PEPCK_ATP PF01293.15 KEG11217.1 - 2.4e-47 161.5 0.0 2.6e-47 161.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase NUDIX_2 PF13869.1 KEG11218.1 - 1.3e-19 70.3 0.3 1.4e-19 70.1 0.2 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase DUF249 PF03158.8 KEG11219.1 - 0.014 14.9 0.4 0.71 9.3 0.1 2.1 1 1 1 2 2 2 0 Multigene family 530 protein RC-P840_PscD PF10657.4 KEG11219.1 - 0.026 14.3 0.0 0.52 10.1 0.0 2.1 2 0 0 2 2 2 0 Photosystem P840 reaction centre protein PscD Vps8 PF12816.2 KEG11219.1 - 0.039 13.2 0.1 0.063 12.5 0.1 1.4 1 1 0 1 1 1 0 Golgi CORVET complex core vacuolar protein 8 MMR_HSR1 PF01926.18 KEG11220.1 - 3.3e-39 133.4 0.0 1.1e-18 67.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KEG11220.1 - 2.2e-22 79.3 0.1 2.4e-11 43.4 0.0 3.8 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KEG11220.1 - 6.5e-18 64.4 0.0 1.2e-09 37.6 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B KH_dom-like PF14714.1 KEG11220.1 - 7.6e-17 61.0 0.3 1.5e-16 60.0 0.2 1.5 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal Miro PF08477.8 KEG11220.1 - 5.5e-16 59.1 0.0 4.5e-07 30.3 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein Dynamin_N PF00350.18 KEG11220.1 - 1.1e-15 57.8 0.1 7.9e-05 22.5 0.0 4.1 3 1 1 4 4 4 3 Dynamin family AIG1 PF04548.11 KEG11220.1 - 3e-12 46.1 0.0 4.4e-06 25.9 0.0 2.4 2 0 0 2 2 2 2 AIG1 family SRPRB PF09439.5 KEG11220.1 - 5.9e-10 38.6 0.0 7.3e-05 22.0 0.0 2.6 2 1 0 2 2 2 2 Signal recognition particle receptor beta subunit DUF258 PF03193.11 KEG11220.1 - 1.8e-07 30.4 0.0 0.013 14.6 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Ras PF00071.17 KEG11220.1 - 3.2e-07 29.8 0.0 0.00025 20.4 0.0 2.9 2 1 0 2 2 2 2 Ras family ABC_tran PF00005.22 KEG11220.1 - 1.6e-06 28.4 0.0 0.072 13.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PduV-EutP PF10662.4 KEG11220.1 - 1.2e-05 24.7 0.0 0.011 15.1 0.0 3.2 3 1 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 KEG11220.1 - 1.3e-05 24.9 0.0 0.014 15.0 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B GBP PF02263.14 KEG11220.1 - 6.9e-05 22.0 0.0 0.065 12.2 0.0 2.3 2 0 0 2 2 2 2 Guanylate-binding protein, N-terminal domain AAA_18 PF13238.1 KEG11220.1 - 0.00038 20.7 0.0 1.6 9.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain Arch_ATPase PF01637.13 KEG11220.1 - 0.00095 18.9 0.0 1.4 8.5 0.0 2.5 2 0 0 2 2 2 2 Archaeal ATPase Septin PF00735.13 KEG11220.1 - 0.0013 17.8 0.0 0.26 10.2 0.0 2.4 2 0 0 2 2 2 1 Septin IIGP PF05049.8 KEG11220.1 - 0.0025 16.6 0.1 0.11 11.2 0.1 2.7 2 1 0 2 2 2 1 Interferon-inducible GTPase (IIGP) AAA_17 PF13207.1 KEG11220.1 - 0.0031 18.3 0.6 4.5 8.1 0.0 3.3 3 2 1 4 4 2 1 AAA domain AAA_10 PF12846.2 KEG11220.1 - 0.0039 16.6 0.0 2.4 7.5 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain AAA_29 PF13555.1 KEG11220.1 - 0.026 14.0 0.0 1.9 8.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_30 PF13604.1 KEG11220.1 - 0.057 12.9 0.0 0.84 9.1 0.1 2.7 2 1 1 3 3 3 0 AAA domain RNA_helicase PF00910.17 KEG11220.1 - 0.077 13.1 0.0 8.2 6.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase IF4E PF01652.13 KEG11224.1 - 1.2e-06 28.1 0.0 1.4e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E PUA PF01472.15 KEG11224.1 - 0.13 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 PUA domain Nnf1 PF03980.9 KEG11225.1 - 2.4 8.1 6.4 3.9 7.5 0.4 3.1 3 0 0 3 3 3 0 Nnf1 DUF2305 PF10230.4 KEG11226.1 - 8.7e-62 208.9 0.1 1e-61 208.7 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 KEG11226.1 - 1.1e-12 48.3 0.0 1.3e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEG11226.1 - 7.3e-09 35.5 0.0 2e-08 34.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KEG11226.1 - 0.047 13.2 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.3 KEG11226.1 - 0.094 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative lysophospholipase SIR2 PF02146.12 KEG11227.1 - 7.8e-59 198.3 0.0 1.1e-58 197.9 0.0 1.2 1 0 0 1 1 1 1 Sir2 family Sporozoite_P67 PF05642.6 KEG11227.1 - 0.0068 14.3 2.3 0.0084 14.0 1.6 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen PI3_PI4_kinase PF00454.22 KEG11228.1 - 0.032 13.6 0.2 0.06 12.8 0.1 1.4 1 0 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase eRF1_1 PF03463.10 KEG11229.1 - 2.1e-32 111.4 0.1 3.7e-32 110.6 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.10 KEG11229.1 - 4e-16 59.2 0.0 2.6e-15 56.6 0.0 2.3 3 0 0 3 3 3 1 eRF1 domain 3 eRF1_2 PF03464.10 KEG11229.1 - 7.3e-16 58.7 0.1 1.1e-15 58.0 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 2 NifU PF01106.12 KEG11230.1 - 1.4e-23 82.4 0.1 2.9e-23 81.4 0.1 1.6 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.6 KEG11230.1 - 3.2e-23 81.1 0.0 5.5e-23 80.3 0.0 1.4 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal Zn_ribbon_2 PF12674.2 KEG11230.1 - 0.12 12.7 0.1 0.26 11.6 0.1 1.5 1 0 0 1 1 1 0 Putative zinc ribbon domain Abhydrolase_6 PF12697.2 KEG11231.1 - 1.5e-24 87.1 0.0 1.9e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEG11231.1 - 2e-21 76.6 0.0 3.1e-21 75.9 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEG11231.1 - 1.5e-14 53.9 0.0 1.2e-13 51.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KEG11231.1 - 9.4e-06 25.2 0.0 0.00053 19.4 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 KEG11231.1 - 0.00015 21.0 0.1 0.011 14.9 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Ndr PF03096.9 KEG11231.1 - 0.00024 19.6 0.0 0.00033 19.2 0.0 1.1 1 0 0 1 1 1 1 Ndr family Peptidase_S15 PF02129.13 KEG11231.1 - 0.0019 17.6 0.0 0.0073 15.7 0.0 1.8 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.13 KEG11231.1 - 0.011 15.0 0.1 0.74 9.0 0.0 2.6 2 1 0 2 2 2 0 Dienelactone hydrolase family DUF2048 PF09752.4 KEG11231.1 - 0.018 13.9 0.1 0.027 13.3 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Esterase_phd PF10503.4 KEG11231.1 - 0.019 14.2 0.1 2.5 7.3 0.0 2.1 2 0 0 2 2 2 0 Esterase PHB depolymerase Esterase PF00756.15 KEG11231.1 - 0.025 13.9 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Abhydrolase_4 PF08386.5 KEG11231.1 - 0.063 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Hydrolase_4 PF12146.3 KEG11231.1 - 0.11 12.3 0.0 0.57 10.0 0.0 2.0 2 0 0 2 2 2 0 Putative lysophospholipase Thioesterase PF00975.15 KEG11231.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_6 PF12697.2 KEG11232.1 - 2.8e-25 89.5 0.1 4.3e-25 88.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEG11232.1 - 8.9e-18 64.6 0.0 8.5e-17 61.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEG11232.1 - 2.3e-12 46.8 0.0 4e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 KEG11232.1 - 0.0043 16.9 0.0 0.0087 15.9 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Thioesterase PF00975.15 KEG11232.1 - 0.0089 16.2 0.0 0.028 14.6 0.0 1.7 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_3 PF07859.8 KEG11232.1 - 0.055 13.0 0.1 0.25 10.8 0.0 2.1 2 1 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KEG11232.1 - 0.058 13.2 0.0 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Putative lysophospholipase DUF2048 PF09752.4 KEG11232.1 - 0.16 10.8 0.2 0.29 9.9 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Kinesin PF00225.18 KEG11235.1 - 5.9e-17 61.3 0.0 9.4e-16 57.4 0.0 2.8 1 1 0 1 1 1 1 Kinesin motor domain UCH PF00443.24 KEG11236.1 - 1.3e-28 99.9 0.0 2.4e-28 99.0 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEG11236.1 - 8.3e-09 35.2 0.0 2.5e-08 33.7 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Kinesin PF00225.18 KEG11237.1 - 3.6e-86 288.9 0.0 5.7e-86 288.2 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Calpain_III PF01067.17 KEG11237.1 - 7.4e-26 90.5 0.0 3.9e-21 75.2 0.0 2.7 2 0 0 2 2 2 2 Calpain large subunit, domain III Arm PF00514.18 KEG11237.1 - 5.9e-10 38.5 0.1 0.0051 16.5 0.0 5.6 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat V-ATPase_H_C PF11698.3 KEG11237.1 - 0.1 12.5 0.0 0.76 9.7 0.0 2.3 2 0 0 2 2 2 0 V-ATPase subunit H HEAT PF02985.17 KEG11237.1 - 4 7.7 4.9 27 5.1 0.0 3.8 4 0 0 4 4 4 0 HEAT repeat Gly-zipper_OmpA PF13436.1 KEG11238.1 - 0.011 15.3 9.3 0.011 15.3 6.4 2.1 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain L27 PF02828.11 KEG11239.1 - 0.081 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 L27 domain DUF4611 PF15387.1 KEG11240.1 - 0.036 14.2 4.2 0.15 12.2 1.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) PGA2 PF07543.7 KEG11240.1 - 2.2 8.0 6.6 0.69 9.7 1.0 2.5 2 0 0 2 2 2 0 Protein trafficking PGA2 dUTPase_2 PF08761.6 KEG11241.1 - 2.2e-41 141.7 0.0 2.9e-41 141.3 0.0 1.2 1 0 0 1 1 1 1 dUTPase Ribosomal_L23 PF00276.15 KEG11242.1 - 1.7e-20 72.7 3.1 1.7e-20 72.7 2.1 1.9 2 1 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.8 KEG11242.1 - 7.2e-10 38.7 16.3 7.2e-10 38.7 11.3 2.3 2 1 0 2 2 2 1 Ribosomal protein L23, N-terminal domain P2 PF07194.6 KEG11242.1 - 0.037 13.8 0.5 0.064 13.1 0.4 1.3 1 0 0 1 1 1 0 P2 response regulator binding domain TusA PF01206.12 KEG11242.1 - 0.077 12.6 0.7 0.11 12.0 0.1 1.6 2 0 0 2 2 2 0 Sulfurtransferase TusA Dapper PF15268.1 KEG11242.1 - 0.44 9.2 5.0 0.52 9.0 3.5 1.0 1 0 0 1 1 1 0 Dapper Ribosomal_L23 PF00276.15 KEG11243.1 - 1.7e-20 72.7 3.1 1.7e-20 72.7 2.1 1.9 2 1 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.8 KEG11243.1 - 9e-11 41.6 15.5 9e-11 41.6 10.7 2.3 2 1 0 2 2 2 1 Ribosomal protein L23, N-terminal domain P2 PF07194.6 KEG11243.1 - 0.037 13.8 0.5 0.064 13.1 0.4 1.3 1 0 0 1 1 1 0 P2 response regulator binding domain TusA PF01206.12 KEG11243.1 - 0.077 12.6 0.7 0.11 12.0 0.1 1.6 2 0 0 2 2 2 0 Sulfurtransferase TusA Dapper PF15268.1 KEG11243.1 - 0.42 9.3 5.0 0.5 9.0 3.4 1.0 1 0 0 1 1 1 0 Dapper PHD PF00628.24 KEG11245.1 - 0.00095 18.8 3.2 0.00095 18.8 2.2 2.1 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 KEG11245.1 - 0.028 13.7 2.8 0.057 12.7 2.0 1.6 1 0 0 1 1 1 0 PHD-finger Peptidase_M23 PF01551.17 KEG11246.1 - 0.09 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M23 FKBP_C PF00254.23 KEG11247.1 - 2.3e-28 98.0 0.0 2.6e-28 97.8 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase MIP PF00230.15 KEG11248.1 - 1.1e-25 90.4 19.4 9.9e-25 87.3 11.7 2.7 1 1 1 2 2 2 2 Major intrinsic protein EF-hand_1 PF00036.27 KEG11249.1 - 6.9e-30 100.0 8.3 1.7e-08 33.1 0.5 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KEG11249.1 - 5.1e-27 93.8 0.8 1e-12 48.0 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KEG11249.1 - 1.6e-24 85.2 8.2 3.6e-12 45.6 0.3 3.9 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 KEG11249.1 - 9.7e-23 77.9 4.5 8.1e-08 31.5 0.1 4.4 3 1 2 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 KEG11249.1 - 2.9e-20 70.5 7.2 6e-06 25.3 0.1 4.1 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 KEG11249.1 - 3.8e-08 33.1 0.1 3.9e-07 29.8 0.0 2.1 2 1 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.2 KEG11249.1 - 6.2e-07 29.1 2.7 0.041 13.6 0.7 3.1 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.5 KEG11249.1 - 0.013 15.4 1.1 3 7.8 0.0 2.8 2 2 0 2 2 2 0 Ca2+ insensitive EF hand DUF3911 PF13050.1 KEG11249.1 - 0.032 14.3 0.1 0.084 12.9 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3911) GlutR_dimer PF00745.15 KEG11249.1 - 0.082 12.8 0.0 2.8 7.9 0.0 2.5 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain EH_Signature PF15611.1 KEG11249.1 - 0.094 11.7 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 EH_Signature domain SPARC_Ca_bdg PF10591.4 KEG11249.1 - 0.11 12.5 0.0 0.29 11.1 0.0 1.7 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region MORN PF02493.15 KEG11250.1 - 1.4e-48 159.8 81.8 6.3e-06 25.6 1.6 12.4 12 0 0 12 12 12 12 MORN repeat Ribosomal_L28e PF01778.12 KEG11252.1 - 4.3e-28 98.0 0.0 8.1e-28 97.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.9 KEG11252.1 - 9e-15 54.6 18.6 9e-15 54.6 12.9 1.9 2 0 0 2 2 2 1 Mak16 protein C-terminal region Exonuc_VII_L PF02601.10 KEG11252.1 - 1.5 7.9 5.7 1.8 7.6 4.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-B_dimeris PF09026.5 KEG11252.1 - 7.4 6.8 12.5 18 5.6 8.6 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pack_C PF02499.10 KEG11253.1 - 0.0064 15.2 0.6 0.4 9.3 0.1 2.3 2 0 0 2 2 2 2 Probable DNA packing protein, C-terminus polyprenyl_synt PF00348.12 KEG11254.1 - 2.8e-57 193.5 0.0 3.6e-49 166.9 0.0 3.0 1 1 1 2 2 2 2 Polyprenyl synthetase zf-DHHC PF01529.15 KEG11255.1 - 2.9e-29 101.6 6.3 2.9e-29 101.6 4.4 1.9 1 1 1 2 2 2 1 DHHC palmitoyltransferase FA PF08736.6 KEG11255.1 - 0.17 11.6 3.1 1 9.1 1.0 2.4 2 0 0 2 2 2 0 FERM adjacent (FA) IncA PF04156.9 KEG11255.1 - 0.88 9.1 5.4 17 4.9 0.0 2.3 2 0 0 2 2 2 0 IncA protein Methyltransf_28 PF02636.12 KEG11256.1 - 2.1e-24 86.3 0.0 2.9e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.15 KEG11256.1 - 5.8e-06 25.5 0.0 1e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.2 KEG11256.1 - 0.00062 20.3 0.0 0.0014 19.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 KEG11256.1 - 0.0029 16.6 0.0 0.0044 16.0 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_26 PF13659.1 KEG11256.1 - 0.004 17.1 0.0 0.0076 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEG11256.1 - 0.0041 16.7 0.0 0.0072 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KEG11256.1 - 0.005 16.5 0.1 0.013 15.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEG11256.1 - 0.042 14.3 0.0 0.085 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain N6_Mtase PF02384.11 KEG11256.1 - 0.22 10.5 0.0 0.33 9.9 0.0 1.1 1 0 0 1 1 1 0 N-6 DNA Methylase Methyltransf_28 PF02636.12 KEG11257.1 - 1e-12 48.0 0.0 1.3e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Mad3_BUB1_I PF08311.7 KEG11257.1 - 0.028 14.1 0.0 4.7 7.0 0.0 2.2 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 Peptidase_M8 PF01457.11 KEG11258.1 - 4.6e-11 41.7 0.0 5e-11 41.6 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin FAM91_C PF14648.1 KEG11259.1 - 1.9e-137 458.8 0.0 8e-137 456.7 0.0 1.9 1 1 0 1 1 1 1 FAM91 C-terminus FAM91_N PF14647.1 KEG11259.1 - 8.9e-107 356.6 0.1 1.2e-106 356.2 0.1 1.1 1 0 0 1 1 1 1 FAM91 N-terminus Vps39_2 PF10367.4 KEG11260.1 - 1.4e-20 73.4 1.8 2.5e-20 72.6 0.1 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 KEG11260.1 - 8.9e-18 64.2 0.0 9.3e-16 57.7 0.0 2.8 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.17 KEG11260.1 - 3.8e-12 46.1 0.0 1.5e-11 44.2 0.0 1.9 2 0 0 2 2 2 1 CNH domain Clathrin PF00637.15 KEG11260.1 - 2.5e-08 33.6 0.1 0.0058 16.2 0.1 2.6 2 0 0 2 2 2 2 Region in Clathrin and VPS PQQ_3 PF13570.1 KEG11260.1 - 0.05 13.8 0.0 0.17 12.1 0.0 2.0 1 0 0 1 1 1 0 PQQ-like domain Abhydrolase_5 PF12695.2 KEG11261.1 - 2.8e-13 49.8 0.0 4.6e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEG11261.1 - 3.7e-07 30.2 0.0 0.045 13.6 0.0 2.7 2 1 1 3 3 3 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEG11261.1 - 3.6e-05 23.0 0.0 9.2e-05 21.7 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 KEG11261.1 - 0.0026 17.3 0.0 0.0049 16.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF818 PF05677.7 KEG11261.1 - 0.011 14.5 0.0 0.016 13.9 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Abhydrolase_2 PF02230.11 KEG11261.1 - 0.039 13.3 0.0 0.58 9.5 0.0 2.5 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase PEX-2N PF09263.5 KEG11261.1 - 0.045 14.0 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Peroxisome biogenesis factor 1, N-terminal DLH PF01738.13 KEG11261.1 - 0.049 12.8 0.0 0.094 11.9 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family SpoU_methylase PF00588.14 KEG11263.1 - 5.8e-12 45.6 0.0 2.6e-06 27.3 0.0 2.3 2 0 0 2 2 2 2 SpoU rRNA Methylase family BBS2_C PF14782.1 KEG11265.1 - 2.9e-61 207.3 3.6 3.2e-61 207.2 2.5 1.0 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal AMP-binding PF00501.23 KEG11266.1 - 2.2e-19 69.1 0.0 1e-10 40.6 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme GAT PF03127.9 KEG11267.1 - 0.06 13.3 3.0 0.34 10.8 2.1 2.2 2 0 0 2 2 2 0 GAT domain DUF2383 PF09537.5 KEG11267.1 - 0.068 13.4 2.6 0.069 13.3 0.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) Striatin PF08232.7 KEG11267.1 - 0.14 12.4 4.3 0.26 11.6 3.0 1.4 1 0 0 1 1 1 0 Striatin family ERM PF00769.14 KEG11267.1 - 0.28 10.6 10.4 0.4 10.1 7.2 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family APG6 PF04111.7 KEG11267.1 - 0.93 8.4 5.3 1.6 7.7 3.7 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 PSP PF04046.11 KEG11268.1 - 1.2e-19 69.4 5.6 2.4e-19 68.4 3.9 1.6 1 0 0 1 1 1 1 PSP DUF382 PF04037.8 KEG11268.1 - 7.2e-14 51.7 1.4 8e-13 48.3 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF382) eIF3_subunit PF08597.5 KEG11269.1 - 0.059 12.9 0.1 0.059 12.9 0.1 2.6 1 1 1 2 2 2 0 Translation initiation factor eIF3 subunit LMBR1 PF04791.11 KEG11270.1 - 1.9e-32 112.5 18.7 3.1e-32 111.8 12.7 1.4 1 1 0 1 1 1 1 LMBR1-like membrane protein SUKH-4 PF14435.1 KEG11270.1 - 0.059 13.0 0.3 0.13 11.9 0.2 1.6 1 0 0 1 1 1 0 SUKH-4 immunity protein RRM_1 PF00076.17 KEG11271.1 - 4.7e-15 54.9 0.0 7e-15 54.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG11271.1 - 4.8e-12 45.6 0.0 7.2e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG11271.1 - 4.7e-08 32.7 0.0 7e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Alg14 PF08660.6 KEG11272.1 - 2.4e-53 180.6 0.2 1.3e-52 178.2 0.0 2.0 2 0 0 2 2 2 1 Oligosaccharide biosynthesis protein Alg14 like Glyco_tran_28_C PF04101.11 KEG11272.1 - 5.4e-29 100.9 0.1 1e-28 100.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 KEG11272.1 - 8.9e-05 21.8 0.3 0.00013 21.3 0.2 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 1 CobA_CobO_BtuR PF02572.10 KEG11272.1 - 0.053 13.1 0.1 0.086 12.4 0.1 1.2 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP DUF4131 PF13567.1 KEG11272.1 - 1.2 8.4 5.5 1.1 8.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) NatB_MDM20 PF09797.4 KEG11273.1 - 6.3e-66 222.5 0.0 9.7e-66 221.9 0.0 1.3 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.1 KEG11273.1 - 1.5e-08 34.7 9.1 0.00061 20.0 0.7 4.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 KEG11273.1 - 0.0048 17.4 9.2 33 5.4 0.0 7.3 5 3 2 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.1 KEG11273.1 - 0.02 15.5 8.2 0.19 12.4 0.1 5.4 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 KEG11273.1 - 0.11 12.4 2.9 18 5.5 0.2 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 KEG11273.1 - 0.11 12.7 1.5 6 7.3 0.0 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat PLAC8 PF04749.12 KEG11274.1 - 5.5e-16 59.0 14.1 7.9e-16 58.5 9.8 1.2 1 0 0 1 1 1 1 PLAC8 family LRR_4 PF12799.2 KEG11275.1 - 2.2e-09 36.7 0.8 0.0011 18.5 0.0 2.9 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG11275.1 - 1.6e-06 27.7 0.2 0.0012 18.5 0.0 3.0 3 0 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 KEG11275.1 - 0.001 18.7 1.0 0.63 10.2 0.4 3.5 2 1 0 2 2 2 1 Leucine Rich Repeat LRR_7 PF13504.1 KEG11275.1 - 0.028 14.5 3.2 0.59 10.5 0.2 3.9 3 0 0 3 3 3 0 Leucine rich repeat LRR_6 PF13516.1 KEG11275.1 - 0.24 11.6 1.4 9.2 6.6 0.2 3.6 3 0 0 3 3 3 0 Leucine Rich repeat SAM_1 PF00536.25 KEG11276.1 - 7e-05 22.9 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 KEG11276.1 - 0.064 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain PGBA_C PF15437.1 KEG11277.1 - 0.12 12.5 1.4 0.17 12.0 1.0 1.3 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal Proteasom_Rpn13 PF04683.8 KEG11279.1 - 6.7e-16 58.1 0.1 1.1e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor DUF192 PF02643.10 KEG11279.1 - 0.11 12.1 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized ACR, COG1430 Pkinase PF00069.20 KEG11280.1 - 9e-18 64.3 0.0 1.2e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG11280.1 - 3.1e-08 32.9 0.0 4.2e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Arf PF00025.16 KEG11281.1 - 2e-78 261.6 0.2 2.2e-78 261.4 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KEG11281.1 - 4.1e-14 52.2 0.0 4.8e-14 52.0 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KEG11281.1 - 1.2e-12 47.4 0.0 1.5e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KEG11281.1 - 6.6e-11 41.5 0.7 1.7e-07 30.3 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KEG11281.1 - 6.3e-10 38.5 0.0 7.4e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KEG11281.1 - 4.1e-07 30.4 0.0 5.8e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KEG11281.1 - 1.7e-05 24.7 0.1 2.2e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 KEG11281.1 - 0.0045 16.0 0.1 0.0061 15.6 0.1 1.4 1 1 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 KEG11281.1 - 0.014 14.8 0.1 0.11 11.8 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 KEG11281.1 - 0.074 12.9 0.1 0.13 12.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain ATP-grasp_4 PF13535.1 KEG11284.1 - 4.6e-29 101.4 0.3 1.2e-28 100.0 0.1 1.8 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KEG11284.1 - 5.8e-12 44.9 0.0 1.9e-07 30.1 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 KEG11284.1 - 2.1e-08 34.2 0.0 5e-08 32.9 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 KEG11284.1 - 0.00097 18.7 0.2 0.0048 16.4 0.1 1.9 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.12 KEG11284.1 - 0.0022 17.3 0.0 0.023 14.0 0.0 2.1 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dynamin_N PF00350.18 KEG11286.1 - 1.5e-20 73.7 0.0 1e-19 71.0 0.0 2.2 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 KEG11286.1 - 3.7e-10 39.7 0.0 8.4e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KEG11286.1 - 0.089 13.2 0.0 17 5.9 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein DUF258 PF03193.11 KEG11286.1 - 0.089 11.9 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 HA2 PF04408.18 KEG11287.1 - 1e-20 73.6 0.1 7.8e-20 70.8 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KEG11287.1 - 3.4e-17 62.3 0.0 8.1e-17 61.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KEG11287.1 - 9.2e-11 41.4 0.0 2.5e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEG11287.1 - 9.8e-10 38.1 0.2 4.7e-09 35.9 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KEG11287.1 - 5.5e-06 26.5 0.0 1.5e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 KEG11287.1 - 2.6e-05 24.1 0.1 0.24 11.2 0.0 2.7 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit T2SE PF00437.15 KEG11287.1 - 7.2e-05 21.8 0.0 0.00014 20.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 KEG11287.1 - 0.0046 16.6 0.0 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 KEG11287.1 - 0.0051 17.0 0.3 0.036 14.2 0.2 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.17 KEG11287.1 - 0.0088 15.5 0.1 0.031 13.7 0.0 1.9 2 1 0 2 2 1 1 SRP54-type protein, GTPase domain UPF0079 PF02367.12 KEG11287.1 - 0.022 14.4 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 KEG11287.1 - 0.025 14.0 0.0 0.061 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.12 KEG11287.1 - 0.029 13.7 0.0 3 7.2 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.1 KEG11287.1 - 0.042 13.2 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KEG11287.1 - 0.048 13.1 0.1 3.5 7.0 0.0 3.1 3 1 1 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain KaiC PF06745.8 KEG11287.1 - 0.054 12.6 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.22 KEG11287.1 - 0.071 13.4 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 KEG11287.1 - 0.087 11.9 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.7 KEG11287.1 - 0.09 12.4 0.0 0.23 11.0 0.0 1.9 1 0 0 1 1 1 0 NACHT domain Flavi_DEAD PF07652.9 KEG11287.1 - 0.12 12.1 0.2 0.26 11.0 0.2 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_16 PF13191.1 KEG11287.1 - 0.12 12.2 0.2 0.69 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Kelch_4 PF13418.1 KEG11288.1 - 3.4e-18 65.1 9.1 3.8e-06 26.5 0.0 6.7 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 KEG11288.1 - 3.6e-16 58.7 3.5 4e-05 23.4 0.1 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.1 KEG11288.1 - 1.7e-15 56.6 3.3 0.0016 18.5 0.0 7.4 8 0 0 8 8 8 3 Galactose oxidase, central domain Kelch_6 PF13964.1 KEG11288.1 - 1.8e-15 56.3 6.7 3.8e-05 23.6 0.0 6.0 4 2 2 6 6 6 3 Kelch motif Kelch_1 PF01344.20 KEG11288.1 - 1.2e-13 50.3 5.7 2.9e-06 26.7 0.0 6.2 7 0 0 7 7 7 3 Kelch motif Kelch_2 PF07646.10 KEG11288.1 - 2.1e-13 49.4 2.0 0.021 14.5 0.0 6.8 6 0 0 6 6 6 4 Kelch motif Glyco_hydro_65m PF03632.10 KEG11289.1 - 2.3e-41 141.7 0.0 3.4e-41 141.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain HAD_2 PF13419.1 KEG11289.1 - 0.00028 21.1 0.1 0.00062 20.0 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Glyco_hydro_65C PF03633.10 KEG11289.1 - 0.0062 16.5 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain Exo_endo_phos PF03372.18 KEG11291.1 - 1e-15 58.3 0.0 1.9e-15 57.5 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KEG11291.1 - 0.065 12.8 0.0 0.6 9.7 0.0 2.5 3 0 0 3 3 3 0 Endonuclease-reverse transcriptase HTH_Tnp_Tc3_2 PF01498.13 KEG11291.1 - 0.089 12.8 0.3 11 6.2 0.0 2.5 2 0 0 2 2 2 0 Transposase SET PF00856.23 KEG11292.1 - 2.5e-06 27.9 0.0 5e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 SET domain Bac_GDH PF05088.7 KEG11292.1 - 0.0074 13.7 0.0 0.01 13.2 0.0 1.1 1 0 0 1 1 1 1 Bacterial NAD-glutamate dehydrogenase dUTPase PF00692.14 KEG11292.1 - 0.13 11.6 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 dUTPase CorA PF01544.13 KEG11293.1 - 0.0073 15.3 2.2 0.017 14.1 1.5 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Peptidase_M24 PF00557.19 KEG11294.1 - 5.9e-44 150.1 0.0 9.7e-44 149.4 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 KEG11294.1 - 8.1e-06 26.3 0.0 0.0078 16.6 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain HAD_2 PF13419.1 KEG11294.1 - 0.093 12.9 0.0 1.5 8.9 0.0 2.3 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase HpcH_HpaI PF03328.9 KEG11295.1 - 2.7e-57 193.1 0.0 3.2e-57 192.9 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Response_reg PF00072.19 KEG11295.1 - 0.029 14.3 0.0 0.074 13.0 0.0 1.7 2 0 0 2 2 2 0 Response regulator receiver domain Pkinase PF00069.20 KEG11297.1 - 4.5e-59 199.7 0.0 1.7e-54 184.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEG11297.1 - 1.1e-35 122.9 0.0 4.6e-24 84.8 0.0 3.0 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.1 KEG11297.1 - 0.00014 20.9 0.0 0.14 11.0 0.0 2.5 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 KEG11297.1 - 0.0023 17.7 0.0 0.0049 16.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KEG11297.1 - 0.0031 16.6 0.0 0.0056 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KEG11297.1 - 0.22 10.8 0.0 0.35 10.1 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Adaptin_N PF01602.15 KEG11298.1 - 0.23 9.7 0.0 0.35 9.1 0.0 1.1 1 0 0 1 1 1 0 Adaptin N terminal region Kinesin PF00225.18 KEG11299.1 - 1e-39 136.2 0.0 1.2e-39 135.9 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain PhoH PF02562.11 KEG11299.1 - 0.031 13.5 0.0 0.05 12.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.1 KEG11299.1 - 0.041 14.0 0.0 0.071 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Kinesin PF00225.18 KEG11300.1 - 1.2e-46 158.9 2.5 2.2e-46 158.1 0.1 2.4 2 0 0 2 2 2 1 Kinesin motor domain tRNA-synt_1c PF00749.16 KEG11300.1 - 0.13 10.9 8.4 0.0082 14.8 1.2 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain Fib_alpha PF08702.5 KEG11300.1 - 0.8 9.8 32.6 0.32 11.1 5.2 4.4 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family Phage_GP20 PF06810.6 KEG11300.1 - 8.9 5.7 26.1 0.53 9.7 4.2 4.4 4 0 0 4 4 4 0 Phage minor structural protein GP20 Acylphosphatase PF00708.13 KEG11301.1 - 1.3e-26 92.5 0.1 1.6e-26 92.2 0.1 1.1 1 0 0 1 1 1 1 Acylphosphatase Reo_sigmaC PF04582.7 KEG11302.1 - 1.8e-05 24.0 16.8 0.00017 20.8 2.9 2.8 1 1 3 4 4 4 3 Reovirus sigma C capsid protein GPAT_N PF14829.1 KEG11302.1 - 0.038 13.6 0.2 0.15 11.7 0.1 2.1 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal LXG PF04740.7 KEG11302.1 - 0.15 11.8 11.4 0.21 11.3 0.1 3.4 1 1 2 3 3 3 0 LXG domain of WXG superfamily Colicin-DNase PF12639.2 KEG11302.1 - 0.2 11.9 1.2 0.62 10.3 0.3 2.1 1 1 1 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin DUF3584 PF12128.3 KEG11302.1 - 0.62 7.3 35.6 0.067 10.5 7.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Prominin PF05478.6 KEG11302.1 - 0.67 7.4 22.3 1.6 6.1 10.8 2.3 1 1 1 2 2 2 0 Prominin Baculo_PEP_C PF04513.7 KEG11302.1 - 0.93 9.3 16.7 0.42 10.4 2.5 3.4 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ADIP PF11559.3 KEG11302.1 - 1.1 9.1 36.4 0.4 10.5 6.5 3.7 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF2115 PF09888.4 KEG11302.1 - 2.1 8.4 6.4 1.7 8.7 2.1 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) Matrilin_ccoil PF10393.4 KEG11302.1 - 2.2 7.7 7.3 1.9 7.9 0.0 4.3 5 0 0 5 5 5 0 Trimeric coiled-coil oligomerisation domain of matrilin PfUIS3 PF11567.3 KEG11302.1 - 2.5 8.3 6.0 3.5 7.8 0.5 3.0 2 1 1 3 3 3 0 Plasmodium falciparum UIS3 membrane protein Vac_Fusion PF02346.11 KEG11302.1 - 3 7.3 12.6 15 5.1 0.7 5.1 4 1 1 5 5 5 0 Chordopoxvirus fusion protein DUF1664 PF07889.7 KEG11302.1 - 4.5 7.0 25.7 7.4 6.3 3.5 4.6 1 1 6 7 7 7 0 Protein of unknown function (DUF1664) DUF2580 PF10824.3 KEG11302.1 - 4.7 7.6 11.0 4.5 7.6 0.0 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF2580) DASH_Dam1 PF08653.5 KEG11302.1 - 5 6.9 6.8 13 5.6 0.1 4.3 4 1 0 4 4 4 0 DASH complex subunit Dam1 Spc7 PF08317.6 KEG11302.1 - 6.6 5.2 29.5 3.8 6.0 8.5 2.6 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF2458 PF10454.4 KEG11302.1 - 8.4 6.2 19.6 0.35 10.7 7.8 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF2458) PIH1 PF08190.7 KEG11303.1 - 1.6e-09 37.6 0.4 1.8e-09 37.5 0.3 1.1 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 Lipase_3 PF01764.20 KEG11304.1 - 0.0087 15.6 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) SPT6_acidic PF14632.1 KEG11306.1 - 1.3 9.2 5.5 0.15 12.2 0.6 1.8 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Pap_E4 PF02711.9 KEG11307.1 - 0.13 13.1 0.6 0.29 11.9 0.4 1.7 1 1 0 1 1 1 0 E4 protein EF-hand_7 PF13499.1 KEG11309.1 - 2.1e-09 37.4 0.0 0.3 11.2 0.0 4.6 5 0 0 5 5 5 4 EF-hand domain pair EF-hand_6 PF13405.1 KEG11309.1 - 1.3e-05 24.6 0.2 0.55 10.2 0.0 4.3 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 KEG11309.1 - 0.0012 17.9 0.5 0.13 11.6 0.1 4.1 4 0 0 4 4 4 1 EF hand EF-hand_5 PF13202.1 KEG11309.1 - 0.1 11.9 0.8 0.87 9.0 0.1 2.6 2 0 0 2 2 2 0 EF hand DAGK_acc PF00609.14 KEG11311.1 - 7.7e-43 146.4 0.0 1.2e-42 145.8 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 KEG11311.1 - 4.4e-17 61.7 0.0 8.3e-17 60.8 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.16 KEG11311.1 - 0.11 11.2 0.1 0.16 10.7 0.1 1.2 1 0 0 1 1 1 0 ATP-NAD kinase PPTA PF01239.17 KEG11312.1 - 2.2e-21 74.2 30.2 4.5e-08 32.1 0.5 5.8 6 0 0 6 6 6 4 Protein prenyltransferase alpha subunit repeat Fumerase PF05681.9 KEG11313.1 - 2.4e-86 289.2 0.0 3.2e-86 288.7 0.0 1.2 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Fumerase_C PF05683.7 KEG11313.1 - 5.4e-80 267.3 0.0 9.2e-80 266.6 0.0 1.4 1 0 0 1 1 1 1 Fumarase C-terminus RRM_1 PF00076.17 KEG11315.1 - 3e-34 116.4 0.0 9.7e-17 60.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG11315.1 - 2.4e-28 97.8 0.1 1.6e-14 53.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG11315.1 - 3.9e-12 45.8 0.0 5.8e-05 22.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KEG11315.1 - 9.4e-06 25.3 0.5 0.15 11.8 0.0 3.7 2 2 0 2 2 2 2 Limkain b1 Spt20 PF12090.3 KEG11315.1 - 0.042 13.2 0.3 0.055 12.8 0.2 1.2 1 0 0 1 1 1 0 Spt20 family GRP PF07172.6 KEG11315.1 - 0.54 10.7 8.1 1.2 9.6 5.6 1.5 1 0 0 1 1 1 0 Glycine rich protein family Ribosomal_L11_N PF03946.9 KEG11316.1 - 3.1e-15 55.3 0.1 6.6e-15 54.3 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 KEG11316.1 - 4.6e-10 39.4 0.3 8.8e-10 38.5 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Torsin PF06309.6 KEG11317.1 - 7e-05 22.7 0.0 0.00016 21.5 0.0 1.5 1 0 0 1 1 1 1 Torsin APS_kinase PF01583.15 KEG11317.1 - 0.0027 17.3 0.0 0.0066 16.1 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_5 PF07728.9 KEG11317.1 - 0.0058 16.3 0.0 0.037 13.7 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.24 KEG11317.1 - 0.04 14.1 0.0 0.09 12.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KEG11317.1 - 0.045 12.8 0.0 0.07 12.1 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KEG11317.1 - 0.055 13.4 0.1 0.25 11.2 0.0 2.1 2 1 1 3 3 3 0 AAA ATPase domain AAA_2 PF07724.9 KEG11317.1 - 0.065 13.1 0.0 0.12 12.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) NB-ARC PF00931.17 KEG11317.1 - 0.092 11.5 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.7 KEG11317.1 - 0.13 11.9 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.1 KEG11317.1 - 0.21 11.9 0.0 0.36 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain RseC_MucC PF04246.7 KEG11318.1 - 7.5 6.1 6.0 2.9 7.4 2.5 1.6 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC FA_desaturase PF00487.19 KEG11320.1 - 4.4e-14 52.5 21.4 6e-14 52.1 14.8 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KEG11320.1 - 1.5e-07 31.1 0.3 0.00017 21.3 0.0 3.1 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain WD40 PF00400.27 KEG11321.1 - 5.4e-76 247.9 30.0 4.3e-11 42.2 0.4 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat NLE PF08154.7 KEG11321.1 - 5.3e-16 58.3 0.0 8.5e-16 57.7 0.0 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain PD40 PF07676.7 KEG11321.1 - 0.00043 19.8 3.9 9.2 6.0 0.0 5.3 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 KEG11321.1 - 0.00088 18.4 0.5 0.47 9.4 0.0 3.5 2 2 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal DUF1227 PF06777.6 KEG11322.1 - 1.6e-44 151.1 0.3 2.9e-44 150.3 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 KEG11322.1 - 1.7e-40 138.2 0.0 4.2e-40 136.9 0.0 1.7 2 0 0 2 2 2 1 DEAD_2 Helicase_C_2 PF13307.1 KEG11322.1 - 3.1e-40 137.8 0.0 6.6e-40 136.7 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD PF00270.24 KEG11322.1 - 0.0002 20.8 0.5 0.091 12.2 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase AAA_19 PF13245.1 KEG11322.1 - 0.00049 19.7 0.0 0.0019 17.9 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 KEG11322.1 - 0.013 15.1 0.2 0.046 13.2 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KEG11322.1 - 0.029 14.5 2.2 0.089 12.9 0.0 2.8 3 1 0 3 3 3 0 AAA domain ResIII PF04851.10 KEG11322.1 - 0.038 13.8 1.4 0.16 11.7 0.1 2.3 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 KEG11322.1 - 0.063 13.0 0.2 2.7 7.7 0.0 2.5 2 0 0 2 2 2 0 Flavivirus DEAD domain Cullin PF00888.17 KEG11323.1 - 2.7e-82 277.2 8.8 3.5e-82 276.8 6.1 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KEG11323.1 - 3.8e-25 87.4 0.5 1.5e-24 85.5 0.3 2.2 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF2096 PF09869.4 KEG11325.1 - 0.011 15.6 1.5 0.015 15.1 0.8 1.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2096) DUF972 PF06156.8 KEG11325.1 - 0.027 14.8 5.6 0.18 12.1 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) FemAB PF02388.11 KEG11325.1 - 0.03 12.9 2.9 0.25 10.0 2.0 1.9 1 1 0 1 1 1 0 FemAB family Rootletin PF15035.1 KEG11325.1 - 0.034 14.1 7.1 0.013 15.4 2.2 1.9 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion TMF_TATA_bd PF12325.3 KEG11325.1 - 0.051 13.3 7.1 0.43 10.3 1.1 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding GAS PF13851.1 KEG11325.1 - 0.057 12.6 5.5 0.12 11.5 1.0 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.7 KEG11325.1 - 0.057 13.1 6.6 0.038 13.7 1.1 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein RSS_P20 PF11757.3 KEG11325.1 - 0.066 13.3 0.4 0.15 12.2 0.2 1.6 1 1 0 1 1 1 0 Suppressor of RNA silencing P21-like RICH PF05062.7 KEG11325.1 - 0.14 12.3 5.5 0.77 9.9 1.6 2.2 2 0 0 2 2 2 0 RICH domain MAD PF05557.8 KEG11325.1 - 0.15 10.1 10.1 0.2 9.7 7.0 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF4194 PF13835.1 KEG11325.1 - 0.35 10.2 3.8 14 5.0 2.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4194) TMCO5 PF14992.1 KEG11325.1 - 0.59 9.2 7.8 1.3 8.1 3.4 2.0 1 1 1 2 2 2 0 TMCO5 family APG6 PF04111.7 KEG11325.1 - 1.3 8.0 10.3 0.6 9.0 4.6 1.8 1 1 1 2 2 2 0 Autophagy protein Apg6 IFP_35_N PF07334.8 KEG11325.1 - 1.3 9.0 3.9 3.4 7.7 0.6 2.8 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF724 PF05266.9 KEG11325.1 - 2.9 7.4 7.0 2.1 7.9 1.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) IncA PF04156.9 KEG11325.1 - 7 6.1 8.4 39 3.7 5.8 2.0 1 1 0 1 1 1 0 IncA protein Pkinase PF00069.20 KEG11326.1 - 2.9e-62 210.1 0.0 3.4e-62 209.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG11326.1 - 1.2e-40 139.2 0.0 1.6e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG11326.1 - 0.00011 21.3 0.0 0.00029 19.9 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 KEG11326.1 - 0.099 12.2 0.1 1.9 8.0 0.0 2.0 1 1 1 2 2 2 0 Choline/ethanolamine kinase APH PF01636.18 KEG11326.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family MAP7 PF05672.6 KEG11327.1 - 1.4 8.2 40.2 0.038 13.3 21.0 2.2 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family A_deaminase_N PF08451.6 KEG11330.1 - 0.0021 18.0 0.3 0.0045 16.9 0.2 1.5 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal Abhydrolase_6 PF12697.2 KEG11331.1 - 4e-23 82.4 0.1 6e-23 81.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KEG11331.1 - 2e-20 72.4 0.4 4e-20 71.4 0.1 1.7 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 KEG11331.1 - 4.3e-19 68.7 0.0 7.8e-19 67.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEG11331.1 - 7.4e-09 35.4 0.0 6.1e-08 32.5 0.0 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KEG11331.1 - 6.7e-06 25.4 0.0 0.002 17.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.13 KEG11331.1 - 0.00029 20.2 0.0 0.00092 18.5 0.0 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family Esterase PF00756.15 KEG11331.1 - 0.00029 20.3 0.0 0.0004 19.9 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.8 KEG11331.1 - 0.0012 18.4 0.1 0.0047 16.5 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KEG11331.1 - 0.0018 17.7 0.0 1.8 7.9 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.13 KEG11331.1 - 0.0047 16.4 0.0 0.032 13.6 0.0 2.1 2 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S10 PF00450.17 KEG11331.1 - 0.013 14.6 0.0 0.43 9.6 0.0 2.0 2 0 0 2 2 2 0 Serine carboxypeptidase PGAP1 PF07819.8 KEG11331.1 - 0.024 14.2 0.0 0.051 13.1 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Thioesterase PF00975.15 KEG11331.1 - 0.03 14.5 0.0 0.045 13.9 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain BAAT_C PF08840.6 KEG11331.1 - 0.039 13.6 0.0 0.12 12.0 0.0 1.7 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Lipase_3 PF01764.20 KEG11331.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) LRR_8 PF13855.1 KEG11332.1 - 2.3e-09 36.8 0.3 0.016 14.9 0.0 4.7 3 2 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.2 KEG11332.1 - 6.9e-08 31.9 0.0 0.012 15.2 0.0 5.1 2 2 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEG11332.1 - 0.00016 21.2 0.8 10 6.5 0.0 5.3 4 2 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.1 KEG11332.1 - 0.00058 19.6 7.6 1.6 9.0 0.1 5.3 6 0 0 6 6 6 2 Leucine Rich repeat LRR_7 PF13504.1 KEG11332.1 - 0.42 11.0 9.8 27 5.5 0.1 5.8 5 1 0 5 5 5 0 Leucine rich repeat EMP24_GP25L PF01105.19 KEG11333.1 - 3.5e-33 114.8 0.1 5e-33 114.3 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4498 PF14926.1 KEG11334.1 - 2e-21 76.2 0.0 3e-11 42.9 0.0 4.6 4 1 0 4 4 4 3 Domain of unknown function (DUF4498) Bd3614_N PF14442.1 KEG11334.1 - 1 9.3 8.2 0.13 12.2 0.4 2.8 3 0 0 3 3 3 0 Bd3614-like deaminase N-terminal Metallophos PF00149.23 KEG11335.1 - 4.8e-16 58.7 0.1 1.1e-15 57.5 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KEG11335.1 - 1e-10 41.6 0.0 1.4e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CutA1 PF03091.10 KEG11336.1 - 2.4e-19 68.8 0.5 2.9e-19 68.6 0.3 1.1 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein Reo_sigmaC PF04582.7 KEG11337.1 - 0.0025 17.0 1.0 0.0042 16.3 0.7 1.3 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Kinesin-relat_1 PF12711.2 KEG11337.1 - 0.097 13.0 5.2 0.24 11.7 3.6 1.7 1 0 0 1 1 1 0 Kinesin motor DivIC PF04977.10 KEG11337.1 - 0.13 11.7 0.7 0.87 9.1 0.0 2.4 1 1 2 3 3 3 0 Septum formation initiator Laminin_II PF06009.7 KEG11337.1 - 0.13 11.9 3.4 0.21 11.3 1.9 1.5 1 1 0 1 1 1 0 Laminin Domain II TPR_MLP1_2 PF07926.7 KEG11337.1 - 0.15 11.8 9.1 0.76 9.5 4.9 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein AAA_13 PF13166.1 KEG11337.1 - 0.2 10.0 1.3 0.27 9.6 0.9 1.0 1 0 0 1 1 1 0 AAA domain BLOC1_2 PF10046.4 KEG11337.1 - 0.42 10.7 2.3 0.95 9.6 1.2 1.8 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc24 PF08286.6 KEG11337.1 - 0.76 9.4 4.2 1.8 8.3 2.9 1.6 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Spc7 PF08317.6 KEG11337.1 - 0.76 8.3 6.7 3.4 6.2 4.7 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein APG6 PF04111.7 KEG11337.1 - 0.92 8.4 4.6 1.4 7.9 3.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 KEG11337.1 - 1.3 6.7 2.8 2.1 6.1 2.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.3 KEG11337.1 - 1.7 8.5 10.6 3.9 7.3 0.4 3.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Atg14 PF10186.4 KEG11337.1 - 1.7 7.4 7.4 3.9 6.3 5.3 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 KEG11337.1 - 2.8 7.4 12.4 4.6 6.8 0.3 2.3 1 1 1 2 2 2 0 IncA protein COG2 PF06148.6 KEG11337.1 - 3.2 7.6 7.1 7.7 6.3 0.3 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 SET PF00856.23 KEG11338.1 - 0.00046 20.5 0.0 0.22 11.8 0.0 2.3 2 0 0 2 2 2 2 SET domain Galactosyl_T PF01762.16 KEG11339.1 - 3.2e-09 36.6 0.0 3.1e-05 23.6 0.0 3.5 2 1 0 2 2 2 2 Galactosyltransferase Galactosyl_T PF01762.16 KEG11340.1 - 0.038 13.6 0.0 0.049 13.2 0.0 1.2 1 0 0 1 1 1 0 Galactosyltransferase IFT57 PF10498.4 KEG11341.1 - 0.0019 16.9 10.8 0.0026 16.5 7.5 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Fb_signal PF08341.6 KEG11341.1 - 0.058 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Fibronectin-binding protein signal sequence Seryl_tRNA_N PF02403.17 KEG11341.1 - 0.2 11.7 6.5 0.092 12.7 1.1 2.4 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF948 PF06103.6 KEG11341.1 - 0.23 11.3 0.6 22 4.9 0.0 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) HALZ PF02183.13 KEG11341.1 - 0.5 10.1 11.9 1.1 9.0 1.6 3.8 5 0 0 5 5 5 0 Homeobox associated leucine zipper GAS PF13851.1 KEG11341.1 - 1.5 7.9 13.8 0.96 8.6 6.8 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF342 PF03961.8 KEG11341.1 - 2.4 6.4 6.8 0.64 8.3 1.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DivIC PF04977.10 KEG11341.1 - 2.5 7.6 9.8 4.1 6.9 0.1 3.6 2 1 2 4 4 4 0 Septum formation initiator Mac PF12464.3 KEG11341.1 - 4.1 7.5 6.4 1.7 8.6 1.6 2.6 2 1 0 2 2 2 0 Maltose acetyltransferase DUF4271 PF14093.1 KEG11342.1 - 0.16 11.6 9.4 0.21 11.2 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) GalKase_gal_bdg PF10509.4 KEG11343.1 - 3e-18 64.8 0.2 1.1e-17 63.0 0.0 2.1 2 0 0 2 2 2 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 KEG11343.1 - 6e-08 32.7 0.0 1.3e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 KEG11343.1 - 0.0021 18.0 0.0 0.0056 16.7 0.0 1.7 1 1 0 1 1 1 1 GHMP kinases N terminal domain MFS_1 PF07690.11 KEG11344.1 - 6.7e-09 34.9 38.7 6.7e-09 34.9 26.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Acyl-CoA_dh_1 PF00441.19 KEG11345.1 - 8.6e-40 136.2 6.5 1.2e-39 135.7 4.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KEG11345.1 - 1.1e-25 90.4 0.0 3.5e-25 88.7 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KEG11345.1 - 1.3e-19 69.4 0.1 2.5e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KEG11345.1 - 1.7e-19 70.3 0.3 2.7e-19 69.7 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SNARE PF05739.14 KEG11346.1 - 3.5e-19 68.2 0.9 3.5e-19 68.2 0.6 2.6 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 KEG11346.1 - 0.0081 16.3 7.5 0.0083 16.2 0.8 2.4 2 0 0 2 2 2 1 Syntaxin Epsilon_antitox PF08998.6 KEG11346.1 - 0.03 14.2 3.0 0.05 13.5 0.5 2.3 2 0 0 2 2 2 0 Bacterial epsilon antitoxin DUF1638 PF07796.6 KEG11346.1 - 0.058 13.0 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1638) YqeY PF09424.5 KEG11346.1 - 0.096 12.5 8.7 0.1 12.4 0.7 2.3 1 1 1 2 2 2 0 Yqey-like protein Syntaxin_2 PF14523.1 KEG11346.1 - 1.5 8.8 6.9 0.68 10.0 1.8 2.3 2 0 0 2 2 2 0 Syntaxin-like protein BTB_2 PF02214.17 KEG11348.1 - 1.3e-16 60.5 0.0 2.2e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF3322 PF11795.3 KEG11348.1 - 0.13 11.8 0.2 0.23 11.0 0.0 1.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) TRAPPC9-Trs120 PF08626.6 KEG11349.1 - 1.2e-07 29.6 0.3 0.0037 14.6 0.0 4.3 2 2 0 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit ART PF01129.13 KEG11349.1 - 0.022 13.8 0.0 0.62 9.1 0.0 2.3 2 0 0 2 2 2 0 NAD:arginine ADP-ribosyltransferase BTB_2 PF02214.17 KEG11350.1 - 1.1e-08 35.1 0.1 4.9e-08 33.0 0.0 2.2 2 1 0 2 2 2 1 BTB/POZ domain HSBP1 PF06825.7 KEG11351.1 - 4.1e-27 93.5 5.5 5.2e-27 93.1 3.8 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 FtsK_SpoIIIE PF01580.13 KEG11351.1 - 0.0012 18.3 0.1 0.0014 18.1 0.1 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family DUF2130 PF09903.4 KEG11351.1 - 0.0021 16.8 0.1 0.0023 16.7 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2130) Helicase_IV_N PF12462.3 KEG11351.1 - 0.0053 16.4 0.0 0.0073 15.9 0.0 1.1 1 0 0 1 1 1 1 DNA helicase IV / RNA helicase N terminal DUF241 PF03087.9 KEG11351.1 - 0.0059 16.1 0.0 0.0068 15.9 0.0 1.1 1 0 0 1 1 1 1 Arabidopsis protein of unknown function BLOC1_2 PF10046.4 KEG11351.1 - 0.0061 16.6 0.3 0.013 15.6 0.2 1.5 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF935 PF06074.7 KEG11351.1 - 0.0075 15.0 1.0 0.008 14.9 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF935) CorA PF01544.13 KEG11351.1 - 0.011 14.7 0.0 0.013 14.5 0.0 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein SF-assemblin PF06705.6 KEG11351.1 - 0.024 13.8 0.1 0.027 13.6 0.1 1.1 1 0 0 1 1 1 0 SF-assemblin/beta giardin Hormone_1 PF00103.15 KEG11351.1 - 0.035 13.4 0.1 0.037 13.3 0.1 1.2 1 0 0 1 1 1 0 Somatotropin hormone family CheZ PF04344.8 KEG11351.1 - 0.039 13.5 0.1 0.042 13.5 0.1 1.1 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ DUF4094 PF13334.1 KEG11351.1 - 0.044 14.1 0.2 0.058 13.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) DUF2884 PF11101.3 KEG11351.1 - 0.047 13.0 1.2 0.056 12.8 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) DHC_N1 PF08385.7 KEG11351.1 - 0.061 11.7 0.3 0.068 11.5 0.2 1.0 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 FliD_C PF07195.7 KEG11351.1 - 0.068 12.4 0.2 0.076 12.3 0.1 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus UPF0449 PF15136.1 KEG11351.1 - 0.084 13.0 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 UPF0184 PF03670.8 KEG11351.1 - 0.09 12.9 0.5 0.14 12.3 0.3 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) Allexi_40kDa PF05549.6 KEG11351.1 - 0.1 11.8 0.3 0.1 11.8 0.2 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein Fzo_mitofusin PF04799.8 KEG11351.1 - 0.11 11.8 0.3 0.12 11.7 0.2 1.1 1 0 0 1 1 1 0 fzo-like conserved region Osmo_CC PF08946.5 KEG11351.1 - 0.12 12.4 0.2 0.18 11.8 0.1 1.3 1 0 0 1 1 1 0 Osmosensory transporter coiled coil Erythro-docking PF09277.6 KEG11351.1 - 0.12 12.1 0.0 0.4 10.4 0.0 1.8 1 1 1 2 2 2 0 Erythronolide synthase, docking GvpK PF05121.7 KEG11351.1 - 0.12 12.2 0.7 0.19 11.5 0.5 1.4 1 1 0 1 1 1 0 Gas vesicle protein K Laminin_I PF06008.9 KEG11351.1 - 0.12 11.6 1.5 0.27 10.5 0.4 1.7 1 1 1 2 2 2 0 Laminin Domain I Hemagglutinin PF00509.13 KEG11351.1 - 0.14 10.3 0.1 0.16 10.0 0.1 1.0 1 0 0 1 1 1 0 Haemagglutinin YvrJ PF12841.2 KEG11351.1 - 0.18 11.1 1.0 0.74 9.1 0.1 2.1 1 1 1 2 2 2 0 YvrJ protein family FlxA PF14282.1 KEG11351.1 - 0.18 11.7 2.1 1.2 9.0 0.1 2.0 1 1 1 2 2 2 0 FlxA-like protein Ank PF00023.25 KEG11352.1 - 2.4e-24 83.8 0.9 6.4e-10 38.3 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 KEG11352.1 - 1.9e-23 82.6 0.3 6.7e-14 52.0 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KEG11352.1 - 6.9e-19 66.0 0.3 5.9e-06 26.0 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 KEG11352.1 - 2.9e-18 65.4 2.6 2.7e-08 33.7 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEG11352.1 - 6.6e-18 64.7 0.1 2.5e-08 34.2 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) AAA PF00004.24 KEG11353.1 - 1.4e-28 99.7 0.0 2.2e-16 60.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEG11353.1 - 2.1e-08 34.3 0.0 0.00022 21.3 0.0 3.6 2 1 1 3 3 3 1 AAA domain Zot PF05707.7 KEG11353.1 - 3.5e-08 33.1 1.1 0.00036 20.0 0.1 4.1 2 2 0 2 2 2 2 Zonular occludens toxin (Zot) AAA_19 PF13245.1 KEG11353.1 - 2.4e-07 30.4 0.5 0.013 15.2 0.0 3.7 3 0 0 3 3 3 2 Part of AAA domain AAA_14 PF13173.1 KEG11353.1 - 1e-06 28.6 0.0 5e-05 23.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEG11353.1 - 5.3e-06 26.5 0.0 0.0027 17.7 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 KEG11353.1 - 7.5e-06 25.4 0.1 0.026 13.9 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_33 PF13671.1 KEG11353.1 - 1.3e-05 25.1 0.0 0.22 11.3 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 KEG11353.1 - 2.8e-05 24.8 0.0 0.091 13.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 KEG11353.1 - 7.1e-05 22.9 0.0 0.064 13.4 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.1 KEG11353.1 - 0.00012 21.5 0.1 0.31 10.4 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KEG11353.1 - 0.00013 22.2 0.0 0.019 15.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 KEG11353.1 - 0.00017 20.4 0.1 0.041 12.5 0.0 2.3 2 0 0 2 2 2 1 TIP49 C-terminus PhoH PF02562.11 KEG11353.1 - 0.00027 20.2 0.0 0.011 15.0 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein AAA_10 PF12846.2 KEG11353.1 - 0.00041 19.8 2.2 0.54 9.6 0.1 3.5 3 1 0 4 4 3 2 AAA-like domain AAA_5 PF07728.9 KEG11353.1 - 0.00063 19.4 0.0 0.19 11.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 KEG11353.1 - 0.0008 18.4 0.2 1.3 7.9 0.0 3.2 2 1 1 3 3 3 1 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.21 KEG11353.1 - 0.0019 17.6 0.0 1.7 8.1 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain RuvB_N PF05496.7 KEG11353.1 - 0.002 17.1 0.0 0.14 11.1 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_23 PF13476.1 KEG11353.1 - 0.002 18.4 0.0 0.063 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 KEG11353.1 - 0.0021 18.3 0.0 1.9 8.8 0.0 3.9 3 1 0 3 3 3 1 ABC transporter Arch_ATPase PF01637.13 KEG11353.1 - 0.0022 17.7 0.0 0.37 10.4 0.0 2.5 2 0 0 2 2 2 1 Archaeal ATPase Mg_chelatase PF01078.16 KEG11353.1 - 0.003 16.7 0.1 0.2 10.8 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 KEG11353.1 - 0.0031 17.0 0.6 3.2 7.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.7 KEG11353.1 - 0.0049 16.5 0.0 0.4 10.3 0.0 2.7 2 0 0 2 2 2 1 NACHT domain ResIII PF04851.10 KEG11353.1 - 0.02 14.7 0.0 0.48 10.2 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_2 PF07724.9 KEG11353.1 - 0.036 13.9 0.0 0.46 10.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) DUF258 PF03193.11 KEG11353.1 - 0.057 12.6 0.1 1.2 8.2 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function, DUF258 APS_kinase PF01583.15 KEG11353.1 - 0.11 12.1 0.1 0.51 9.9 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase Torsin PF06309.6 KEG11353.1 - 0.16 11.8 0.0 3.8 7.4 0.0 2.7 2 0 0 2 2 2 0 Torsin AAA_24 PF13479.1 KEG11353.1 - 0.3 10.6 0.9 0.57 9.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain zf-CCHC_4 PF14392.1 KEG11354.1 - 0.0054 16.3 0.3 0.0091 15.6 0.2 1.4 1 0 0 1 1 1 1 Zinc knuckle Rhodanese PF00581.15 KEG11355.1 - 1.1e-13 51.4 0.0 1.4e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain AAA_12 PF13087.1 KEG11356.1 - 4e-52 176.5 0.0 8e-52 175.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KEG11356.1 - 6.8e-47 160.0 1.0 8.4e-45 153.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 KEG11356.1 - 1.7e-10 40.4 0.0 9.9e-10 38.0 0.0 2.4 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KEG11356.1 - 7.5e-10 38.7 0.0 0.00067 19.2 0.1 2.8 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.16 KEG11356.1 - 4.9e-05 22.7 0.1 0.0036 16.6 0.0 3.1 4 0 0 4 4 4 1 UvrD/REP helicase N-terminal domain ResIII PF04851.10 KEG11356.1 - 0.02 14.7 0.0 0.41 10.4 0.0 2.9 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KEG11356.1 - 0.03 14.4 0.1 0.32 11.1 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.1 KEG11356.1 - 0.11 12.4 2.3 0.35 10.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.1 KEG11356.1 - 0.13 12.5 2.8 1.4 9.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain DUF240 PF03086.9 KEG11356.1 - 0.22 11.1 0.4 0.45 10.1 0.3 1.4 1 0 0 1 1 1 0 MG032/MG096/MG288 family 2 Terminase_1 PF03354.10 KEG11356.1 - 0.8 8.0 0.0 1.4 7.2 0.0 1.3 1 0 0 1 1 1 0 Phage Terminase Bromodomain PF00439.20 KEG11358.1 - 2.7e-15 56.0 0.0 4.2e-09 36.2 0.0 3.3 3 0 0 3 3 3 2 Bromodomain DUF3909 PF13077.1 KEG11358.1 - 0.0022 17.8 0.2 0.0072 16.1 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3909) Apc15p PF05841.6 KEG11358.1 - 3.9 8.2 13.8 5.3 7.7 3.3 2.5 2 0 0 2 2 2 0 Apc15p protein Caudal_act PF04731.7 KEG11360.1 - 0.46 10.7 4.5 0.91 9.8 3.1 1.5 1 1 0 1 1 1 0 Caudal like protein activation region Adaptin_N PF01602.15 KEG11361.1 - 5.1e-97 325.3 7.0 6.1e-97 325.1 4.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 KEG11361.1 - 1.1e-15 57.9 0.2 2.1e-15 57.0 0.1 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain HECT PF00632.20 KEG11362.1 - 2.2e-51 174.9 0.0 3.7e-51 174.1 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WWE PF02825.15 KEG11362.1 - 0.028 13.8 0.1 0.07 12.5 0.0 1.7 1 0 0 1 1 1 0 WWE domain Xpo1 PF08389.7 KEG11362.1 - 0.061 13.2 0.1 10 5.9 0.0 2.8 2 0 0 2 2 2 0 Exportin 1-like protein eRF1_1 PF03463.10 KEG11362.1 - 0.079 12.5 0.0 0.23 11.0 0.0 1.7 1 0 0 1 1 1 0 eRF1 domain 1 DivIC PF04977.10 KEG11363.1 - 0.043 13.3 0.3 0.078 12.4 0.2 1.4 1 0 0 1 1 1 0 Septum formation initiator PI3_PI4_kinase PF00454.22 KEG11364.1 - 1e-46 159.3 1.0 2.1e-46 158.3 0.1 2.0 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 KEG11364.1 - 4.6e-30 104.7 0.3 1.8e-29 102.8 0.2 2.1 1 1 0 1 1 1 1 FAT domain Rapamycin_bind PF08771.6 KEG11364.1 - 4.3e-21 74.8 0.1 2e-20 72.7 0.1 2.3 1 0 0 1 1 1 1 Rapamycin binding domain DUF3385 PF11865.3 KEG11364.1 - 9.2e-20 71.1 0.3 9.2e-20 71.1 0.2 4.0 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) FATC PF02260.15 KEG11364.1 - 3.8e-15 55.0 0.1 8.9e-15 53.8 0.1 1.7 1 0 0 1 1 1 1 FATC domain PDZ PF00595.19 KEG11364.1 - 1.2e-06 28.6 0.7 3e-06 27.3 0.5 1.7 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KEG11364.1 - 7.4e-05 22.5 0.2 0.0002 21.2 0.1 1.7 1 0 0 1 1 1 1 PDZ domain HEAT_2 PF13646.1 KEG11364.1 - 7.7e-05 22.9 3.1 0.086 13.1 0.1 4.6 2 1 0 2 2 2 2 HEAT repeats HEAT PF02985.17 KEG11364.1 - 0.002 18.0 4.5 0.039 14.0 0.1 4.8 5 0 0 5 5 4 1 HEAT repeat Tricorn_PDZ PF14685.1 KEG11364.1 - 0.0044 16.7 0.1 0.012 15.3 0.1 1.7 1 0 0 1 1 1 1 Tricorn protease PDZ domain TPR_11 PF13414.1 KEG11364.1 - 0.014 14.9 0.0 0.099 12.3 0.0 2.5 2 0 0 2 2 2 0 TPR repeat TPR_17 PF13431.1 KEG11364.1 - 0.044 13.9 0.0 2.7 8.3 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat LBP_BPI_CETP PF01273.20 KEG11365.1 - 0.0003 20.1 0.8 0.00099 18.4 0.1 2.1 3 1 0 3 3 3 1 LBP / BPI / CETP family, N-terminal domain NIF PF03031.13 KEG11366.1 - 2.9e-25 88.7 0.0 3.8e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF705 PF05152.7 KEG11366.1 - 2.3e-09 36.6 0.0 3e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF705) Hydrolase PF00702.21 KEG11366.1 - 0.0017 18.8 0.0 0.075 13.4 0.0 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KEG11366.1 - 0.0034 17.6 0.1 0.024 14.8 0.1 2.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KEG11366.1 - 0.096 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase PABP PF00658.13 KEG11367.1 - 3.3e-29 100.3 0.2 3.8e-29 100.1 0.2 1.0 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain LON PF02190.11 KEG11367.1 - 0.014 15.1 0.1 0.015 15.0 0.1 1.1 1 0 0 1 1 1 0 ATP-dependent protease La (LON) domain AIG1 PF04548.11 KEG11367.1 - 0.1 11.7 0.0 0.14 11.2 0.0 1.3 1 1 0 1 1 1 0 AIG1 family MMR_HSR1 PF01926.18 KEG11367.1 - 0.12 12.3 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KEG11369.1 - 2.5e-41 141.1 0.1 2.6e-39 134.6 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KEG11369.1 - 3.9e-06 26.9 0.1 1.1e-05 25.4 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 KEG11369.1 - 0.00019 21.3 0.0 0.00061 19.7 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 KEG11369.1 - 0.00035 20.6 0.8 0.0033 17.5 0.2 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 FeoB_N PF02421.13 KEG11369.1 - 0.0012 18.1 0.1 0.0074 15.5 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B G-alpha PF00503.15 KEG11369.1 - 0.0092 14.7 0.0 0.016 13.8 0.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit UBA PF00627.26 KEG11369.1 - 0.063 13.1 0.1 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain DUF2009 PF09418.5 KEG11370.1 - 3.3e-205 682.1 0.0 3.8e-205 682.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) RNA_pol_Rpc4 PF05132.9 KEG11371.1 - 4.6e-12 46.0 0.1 8.7e-11 41.9 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase III RPC4 BBS1 PF14779.1 KEG11372.1 - 2.3e-60 203.7 0.0 3.8e-60 203.0 0.0 1.3 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 1 BBS2_Mid PF14783.1 KEG11372.1 - 3.5e-07 29.9 0.0 0.21 11.3 0.0 3.7 2 1 2 4 4 4 3 Ciliary BBSome complex subunit 2, middle region PHTB1_N PF14727.1 KEG11372.1 - 0.0039 16.1 0.0 0.044 12.7 0.0 2.2 2 1 1 3 3 3 1 PTHB1 N-terminus Syntaxin-18_N PF10496.4 KEG11373.1 - 0.05 13.4 0.2 0.072 12.9 0.1 1.2 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus Herpes_UL45 PF05473.7 KEG11373.1 - 0.075 12.4 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 UL45 protein Nucleotid_trans PF03407.11 KEG11374.1 - 6.1e-47 160.1 0.3 9.1e-47 159.5 0.2 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF2769 PF10967.3 KEG11374.1 - 0.09 13.0 1.0 20 5.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2769) Oxidored_FMN PF00724.15 KEG11375.1 - 1.3e-68 231.5 0.0 1.6e-68 231.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1903 PF08991.5 KEG11377.1 - 1.5e-05 25.0 7.2 0.00069 19.7 0.9 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1903) CHCH PF06747.8 KEG11377.1 - 8.5e-05 22.3 9.0 0.0061 16.4 3.0 2.4 2 0 0 2 2 2 2 CHCH domain CHORD PF04968.7 KEG11377.1 - 0.023 14.9 0.9 0.045 14.0 0.6 1.5 1 0 0 1 1 1 0 CHORD Pet191_N PF10203.4 KEG11377.1 - 0.57 10.2 10.1 3.2 7.8 0.1 3.1 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 KEG11377.1 - 3.6 7.4 11.7 2.1 8.1 3.6 2.8 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like MORN PF02493.15 KEG11378.1 - 3.2e-32 108.3 51.1 0.00014 21.3 2.0 10.2 10 1 0 10 10 10 9 MORN repeat PH PF00169.24 KEG11378.1 - 7.5e-05 22.8 0.0 0.00014 22.0 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KEG11378.1 - 0.09 13.0 0.1 1 9.6 0.1 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain Tropomyosin PF00261.15 KEG11379.1 - 5.3e-06 25.6 25.0 0.0011 18.0 1.7 3.5 2 1 1 3 3 3 2 Tropomyosin Tropomyosin_1 PF12718.2 KEG11379.1 - 7.6e-05 22.5 26.8 0.057 13.2 1.7 3.8 2 1 1 3 3 3 3 Tropomyosin like GAS PF13851.1 KEG11379.1 - 0.00048 19.3 11.8 0.00048 19.3 8.2 2.2 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding ADIP PF11559.3 KEG11379.1 - 0.014 15.3 24.8 0.7 9.7 1.5 3.3 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding Microtub_assoc PF07989.6 KEG11379.1 - 0.016 15.0 16.1 0.41 10.5 0.8 3.9 2 1 1 3 3 3 0 Microtubule associated Mto2_bdg PF12808.2 KEG11379.1 - 0.017 15.2 2.4 0.017 15.2 1.6 4.0 4 1 0 4 4 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region HALZ PF02183.13 KEG11379.1 - 0.058 13.1 0.5 0.058 13.1 0.4 4.5 4 1 1 5 5 5 0 Homeobox associated leucine zipper Cep57_CLD_2 PF14197.1 KEG11379.1 - 0.07 13.0 26.9 0.82 9.6 1.0 4.4 4 0 0 4 4 4 0 Centrosome localisation domain of PPC89 DUF972 PF06156.8 KEG11379.1 - 0.092 13.1 20.7 0.062 13.6 1.4 3.8 2 1 2 4 4 4 0 Protein of unknown function (DUF972) Rootletin PF15035.1 KEG11379.1 - 0.097 12.6 26.7 0.87 9.5 1.5 3.2 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion Lectin_N PF03954.9 KEG11379.1 - 0.21 10.9 7.8 0.26 10.6 1.7 2.9 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain IncA PF04156.9 KEG11379.1 - 0.23 11.0 30.8 0.39 10.2 12.6 2.9 1 1 0 2 2 2 0 IncA protein WD40_alt PF14077.1 KEG11379.1 - 0.37 10.4 5.9 39 3.9 0.0 4.5 4 1 1 5 5 5 0 Alternative WD40 repeat motif Mnd1 PF03962.10 KEG11379.1 - 0.49 10.0 19.3 2 8.0 7.0 3.1 2 1 0 2 2 2 0 Mnd1 family IFP_35_N PF07334.8 KEG11379.1 - 0.75 9.8 18.6 2.8 7.9 0.5 4.9 3 2 2 5 5 4 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus bZIP_1 PF00170.16 KEG11379.1 - 0.76 9.7 16.5 1.4 8.9 0.8 4.6 3 1 0 3 3 3 0 bZIP transcription factor Snapin_Pallidin PF14712.1 KEG11379.1 - 1.2 9.4 17.1 5.2 7.4 2.0 3.6 3 1 0 3 3 3 0 Snapin/Pallidin Reo_sigmaC PF04582.7 KEG11379.1 - 1.3 8.0 5.3 1.5 7.9 1.4 2.2 2 1 0 2 2 2 0 Reovirus sigma C capsid protein DUF641 PF04859.7 KEG11379.1 - 1.7 8.4 16.1 0.39 10.4 0.4 3.4 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) Kinetocho_Slk19 PF12709.2 KEG11379.1 - 2.1 8.4 14.8 5.6 7.1 0.1 3.9 3 1 0 3 3 3 0 Central kinetochore-associated Seryl_tRNA_N PF02403.17 KEG11379.1 - 2.5 8.1 21.5 7.5 6.6 1.4 4.3 2 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Spectrin PF00435.16 KEG11379.1 - 2.6 8.3 21.7 2.7 8.3 1.2 3.8 2 1 2 4 4 4 0 Spectrin repeat CCDC-167 PF15188.1 KEG11379.1 - 2.7 7.9 17.8 7.6 6.5 0.3 4.3 2 1 2 4 4 4 0 Coiled-coil domain-containing protein 167 Fez1 PF06818.10 KEG11379.1 - 3.9 7.4 25.2 2 8.4 2.7 3.0 1 1 2 3 3 3 0 Fez1 DUF4446 PF14584.1 KEG11379.1 - 3.9 7.2 8.3 17 5.2 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) MT PF12777.2 KEG11379.1 - 3.9 6.1 8.8 0.053 12.2 0.6 1.9 3 0 0 3 3 3 0 Microtubule-binding stalk of dynein motor Filament PF00038.16 KEG11379.1 - 4.3 6.7 23.0 5.4 6.3 3.3 3.1 2 1 1 3 3 3 0 Intermediate filament protein KLRAQ PF10205.4 KEG11379.1 - 4.5 7.3 19.1 0.58 10.2 2.1 3.6 2 1 1 3 3 3 0 Predicted coiled-coil domain-containing protein ATG16 PF08614.6 KEG11379.1 - 5.1 6.8 25.9 3.6 7.3 2.6 3.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Jnk-SapK_ap_N PF09744.4 KEG11379.1 - 5.6 6.9 17.1 3.8 7.4 4.3 3.0 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 MAD PF05557.8 KEG11379.1 - 5.8 4.8 23.8 0.65 8.0 2.1 2.9 2 1 0 2 2 2 0 Mitotic checkpoint protein Cep57_MT_bd PF06657.8 KEG11379.1 - 6 6.8 14.1 4.2 7.3 0.9 3.4 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DUF2935 PF11155.3 KEG11379.1 - 6.1 6.9 6.4 1.2e+02 2.7 4.5 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) CENP-H PF05837.7 KEG11379.1 - 6.2 7.0 22.6 1.2 9.3 3.9 3.4 2 1 1 3 3 3 0 Centromere protein H (CENP-H) Spc24 PF08286.6 KEG11379.1 - 6.9 6.4 21.6 1.3 8.7 1.4 3.9 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 UPF0242 PF06785.6 KEG11379.1 - 8.4 4.9 13.5 16 4.0 5.7 2.4 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) ERM PF00769.14 KEG11379.1 - 9.2 5.7 26.5 0.62 9.5 7.0 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Rab5-bind PF09311.6 KEG11380.1 - 0.0047 16.8 17.9 0.0047 16.8 12.4 7.5 5 2 1 7 7 7 4 Rabaptin-like protein Reo_sigmaC PF04582.7 KEG11380.1 - 0.012 14.8 38.3 0.29 10.2 3.2 6.4 5 1 1 6 6 6 0 Reovirus sigma C capsid protein CDP-OH_P_transf PF01066.16 KEG11381.1 - 1.2e-17 64.0 6.2 1.2e-17 64.0 4.3 1.6 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase zf-CHY PF05495.7 KEG11382.1 - 0.058 13.5 3.1 1.8 8.8 2.1 2.3 1 1 0 1 1 1 0 CHY zinc finger DUF3133 PF11331.3 KEG11382.1 - 0.066 12.7 0.1 0.066 12.7 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3133) Stc1 PF12898.2 KEG11382.1 - 0.18 11.8 0.4 0.18 11.8 0.3 2.3 1 1 1 2 2 2 0 Stc1 domain Spt4 PF06093.8 KEG11382.1 - 0.24 11.3 2.5 5.2 7.0 0.2 2.4 1 1 1 2 2 2 0 Spt4/RpoE2 zinc finger RNHCP PF12647.2 KEG11382.1 - 0.91 9.3 6.9 0.61 9.9 2.3 2.2 1 1 1 2 2 2 0 RNHCP domain DUF1254 PF06863.7 KEG11383.1 - 0.11 12.2 0.1 0.28 11.0 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1254) RRM_6 PF14259.1 KEG11384.1 - 0.00084 19.2 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2681 PF10883.3 KEG11384.1 - 2.3 8.4 7.6 0.2 11.8 1.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF4407 PF14362.1 KEG11384.1 - 2.7 6.8 15.4 53 2.6 10.5 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Pkinase PF00069.20 KEG11385.1 - 6.5e-58 195.9 0.0 2e-57 194.3 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG11385.1 - 3.2e-35 121.4 0.0 4.4e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG11385.1 - 8.7e-08 31.4 0.0 1.6e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KEG11385.1 - 0.0044 16.3 0.0 0.0098 15.2 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KEG11385.1 - 0.012 15.3 2.7 0.029 14.1 1.9 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 KEG11385.1 - 0.018 14.1 0.1 0.035 13.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family JAB PF01398.16 KEG11386.1 - 3.6e-22 78.2 0.1 6.6e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 KEG11386.1 - 3.4e-09 36.1 1.7 3e-08 33.1 1.1 2.2 1 1 0 1 1 1 1 Prokaryotic homologs of the JAB domain DGF-1_5 PF11038.3 KEG11386.1 - 0.034 13.3 0.4 0.054 12.6 0.3 1.2 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 5 BTB PF00651.26 KEG11387.1 - 1.1e-09 38.2 0.1 0.00038 20.4 0.0 3.1 2 1 0 2 2 2 2 BTB/POZ domain ZZ PF00569.12 KEG11387.1 - 0.81 9.2 3.2 7.7 6.1 0.7 2.4 2 0 0 2 2 2 0 Zinc finger, ZZ type EAP30 PF04157.11 KEG11388.1 - 0.15 11.2 3.7 0.71 8.9 0.0 2.5 3 0 0 3 3 3 0 EAP30/Vps36 family Cep57_MT_bd PF06657.8 KEG11389.1 - 0.00014 21.6 2.3 0.00014 21.6 1.6 4.4 2 1 1 4 4 4 1 Centrosome microtubule-binding domain of Cep57 Metal_resist PF13801.1 KEG11389.1 - 0.028 14.3 0.9 0.028 14.3 0.6 4.2 2 1 2 4 4 4 0 Heavy-metal resistance AAA_27 PF13514.1 KEG11389.1 - 0.42 8.2 35.5 0.29 8.7 17.3 2.1 2 0 0 2 2 2 0 AAA domain Mit_KHE1 PF10173.4 KEG11389.1 - 0.57 10.0 5.8 2.6 7.8 3.1 2.2 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related CENP-F_leu_zip PF10473.4 KEG11389.1 - 2.6 7.8 45.5 0.027 14.3 17.9 3.2 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Parvo_coat PF00740.13 KEG11389.1 - 3.6 6.4 6.2 6.8 5.5 4.3 1.4 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Baculo_PEP_C PF04513.7 KEG11389.1 - 4.3 7.1 12.6 1.9 8.3 0.6 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.1 KEG11389.1 - 4.8 6.3 36.4 2.2 7.3 14.1 3.2 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF3584 PF12128.3 KEG11389.1 - 6.5 3.9 38.5 0.31 8.3 18.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Toxin_39 PF15500.1 KEG11389.1 - 7.5 6.7 16.8 7.1 6.8 3.9 3.4 2 1 1 3 3 3 0 Putative RNase-like toxin SPX PF03105.14 KEG11389.1 - 9.1 5.9 26.5 19 4.9 0.2 2.2 1 1 0 2 2 2 0 SPX domain Galanin PF01296.13 KEG11390.1 - 2.7 7.8 5.0 0.56 10.0 0.5 2.1 2 0 0 2 2 2 0 Galanin STAG PF08514.6 KEG11391.1 - 1.1e-15 57.3 0.0 3.6e-15 55.6 0.0 1.9 1 0 0 1 1 1 1 STAG domain PS-DH PF14765.1 KEG11392.1 - 0.052 12.6 0.6 0.072 12.2 0.4 1.2 1 0 0 1 1 1 0 Polyketide synthase dehydratase Menin PF05053.8 KEG11392.1 - 2.2 6.3 5.7 2.5 6.1 4.0 1.0 1 0 0 1 1 1 0 Menin Proteasome PF00227.21 KEG11393.1 - 3.8e-54 182.8 0.0 4.7e-54 182.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KEG11393.1 - 5.7e-14 51.1 0.1 1.5e-13 49.8 0.1 1.8 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Clathrin PF00637.15 KEG11394.1 - 9.7e-166 543.9 33.6 4.5e-29 100.8 0.3 8.3 8 0 0 8 8 8 8 Region in Clathrin and VPS Clathrin_H_link PF13838.1 KEG11394.1 - 4.7e-19 68.0 0.0 5.6e-18 64.5 0.0 2.8 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.15 KEG11394.1 - 1.2e-18 66.0 0.0 0.0055 16.9 0.0 6.8 7 0 0 7 7 7 5 Clathrin propeller repeat Clathrin-link PF09268.5 KEG11394.1 - 1.8e-13 49.1 0.1 1.1e-12 46.7 0.0 2.4 2 0 0 2 2 2 1 Clathrin, heavy-chain linker TPR_7 PF13176.1 KEG11394.1 - 8.2e-05 22.1 0.2 4.8 7.2 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat ATP13 PF12921.2 KEG11394.1 - 0.018 14.3 0.0 0.053 12.8 0.0 1.8 1 0 0 1 1 1 0 Mitochondrial ATPase expression Coatomer_WDAD PF04053.9 KEG11394.1 - 0.091 11.5 8.4 0.024 13.4 0.4 3.5 5 0 0 5 5 5 0 Coatomer WD associated region TPR_1 PF00515.23 KEG11394.1 - 0.13 11.9 9.4 4.5 7.0 0.1 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEG11394.1 - 0.24 12.1 23.3 1.3 9.8 0.2 9.1 10 1 1 11 11 11 0 Tetratricopeptide repeat TMF_DNA_bd PF12329.3 KEG11395.1 - 0.0059 16.3 3.6 0.0059 16.3 2.5 2.3 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding DUF728 PF05304.7 KEG11395.1 - 0.024 14.8 0.9 0.052 13.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF728) Striatin PF08232.7 KEG11396.1 - 0.00072 19.8 8.6 0.0016 18.7 6.0 1.6 1 0 0 1 1 1 1 Striatin family DUF3552 PF12072.3 KEG11396.1 - 0.0011 18.1 20.4 0.0017 17.6 14.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) NHase_beta PF02211.10 KEG11396.1 - 0.0012 18.5 1.2 0.0022 17.7 0.9 1.3 1 0 0 1 1 1 1 Nitrile hydratase beta subunit OmpH PF03938.9 KEG11396.1 - 0.029 14.3 29.0 0.059 13.3 20.1 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) V_ATPase_I PF01496.14 KEG11396.1 - 0.12 10.2 10.4 0.16 9.7 7.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Borrelia_P83 PF05262.6 KEG11396.1 - 0.25 9.5 13.3 0.37 8.9 9.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Macoilin PF09726.4 KEG11396.1 - 0.49 8.6 13.6 0.69 8.1 9.4 1.1 1 0 0 1 1 1 0 Transmembrane protein AAA_23 PF13476.1 KEG11396.1 - 0.58 10.4 15.5 0.83 9.9 10.7 1.2 1 0 0 1 1 1 0 AAA domain DUF775 PF05603.7 KEG11396.1 - 0.95 8.9 9.1 0.91 8.9 4.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF775) APG6 PF04111.7 KEG11396.1 - 1.5 7.7 18.8 2.2 7.2 13.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4557 PF15101.1 KEG11396.1 - 8 6.2 16.2 15 5.3 11.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Serinc PF03348.10 KEG11397.1 - 1.2e-55 188.9 27.9 3.6e-42 144.5 11.9 2.0 1 1 1 2 2 2 2 Serine incorporator (Serinc) EF-hand_6 PF13405.1 KEG11398.1 - 2.7e-09 36.1 12.8 0.021 14.6 0.1 7.2 7 0 0 7 7 7 3 EF-hand domain EF-hand_7 PF13499.1 KEG11398.1 - 1.2e-06 28.5 3.3 8.5 6.6 0.0 6.3 7 0 0 7 7 7 1 EF-hand domain pair EF-hand_8 PF13833.1 KEG11398.1 - 2e-05 24.1 0.3 0.054 13.1 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.27 KEG11398.1 - 0.0013 17.8 0.5 5.9 6.4 0.0 5.2 4 0 0 4 4 4 1 EF hand DUF1999 PF09390.5 KEG11398.1 - 0.003 16.9 0.1 0.02 14.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1999) Coat_F PF07875.7 KEG11398.1 - 0.16 12.1 0.1 1.9 8.6 0.0 2.5 2 0 0 2 2 2 0 Coat F domain DUF3037 PF11236.3 KEG11398.1 - 0.18 11.8 1.3 33 4.5 0.0 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF3037) SNF2_N PF00176.18 KEG11400.1 - 9.3e-15 54.1 0.0 8.2e-14 51.0 0.0 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain FHA PF00498.21 KEG11400.1 - 8.2e-08 32.2 0.0 1.9e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 FHA domain Helicase_C PF00271.26 KEG11400.1 - 2.1e-05 24.2 0.0 7.2e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEG11400.1 - 0.012 15.4 0.0 0.34 10.7 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit COX6B PF02297.12 KEG11401.1 - 0.013 15.5 1.6 0.013 15.5 1.1 2.8 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb G6PD_bact PF10786.4 KEG11401.1 - 0.025 13.9 1.5 3.1 7.1 0.0 2.1 2 0 0 2 2 2 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) Pet191_N PF10203.4 KEG11401.1 - 0.052 13.5 5.5 0.48 10.5 0.6 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.8 KEG11401.1 - 0.66 9.9 3.3 19 5.3 0.2 3.1 2 1 0 2 2 2 0 CHCH domain UPF0203 PF05254.7 KEG11401.1 - 0.77 9.6 9.9 23 4.9 0.2 3.7 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0203) TLD PF07534.11 KEG11402.1 - 2.9e-23 82.4 0.0 9.3e-22 77.5 0.1 2.5 2 1 0 2 2 2 1 TLD Apolipoprotein PF01442.13 KEG11403.1 - 4.6e-05 23.0 7.5 4.6e-05 23.0 5.2 2.0 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.7 KEG11403.1 - 0.012 15.4 2.7 1.1 9.0 0.0 3.3 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2730 PF10805.3 KEG11403.1 - 0.21 11.3 10.3 0.68 9.6 0.1 4.1 2 1 2 4 4 4 0 Protein of unknown function (DUF2730) Sipho_Gp157 PF05565.6 KEG11403.1 - 0.29 10.7 4.5 1.4 8.5 0.1 2.7 2 1 1 3 3 3 0 Siphovirus Gp157 Allexi_40kDa PF05549.6 KEG11403.1 - 0.6 9.3 5.6 6.4 5.9 1.0 2.5 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF3552 PF12072.3 KEG11403.1 - 1.4 8.0 8.8 0.47 9.6 3.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Clathrin PF00637.15 KEG11404.1 - 1.1e-10 41.2 0.0 5.9e-10 38.9 0.0 2.0 2 0 0 2 2 2 1 Region in Clathrin and VPS F-box PF00646.28 KEG11404.1 - 1.5e-06 27.7 0.1 2.5e-05 23.8 0.0 2.9 2 0 0 2 2 2 1 F-box domain LIM PF00412.17 KEG11404.1 - 0.011 15.7 2.8 0.011 15.7 2.0 3.8 4 1 0 4 4 4 0 LIM domain NPV_P10 PF05531.7 KEG11405.1 - 0.00023 21.3 2.2 0.4 10.9 0.0 2.4 1 1 1 2 2 2 2 Nucleopolyhedrovirus P10 protein Apolipoprotein PF01442.13 KEG11405.1 - 0.0014 18.2 0.4 0.002 17.7 0.3 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain EzrA PF06160.7 KEG11405.1 - 0.0016 16.7 0.4 0.0019 16.5 0.3 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA priB_priC PF07445.7 KEG11405.1 - 0.0098 15.3 0.4 0.014 14.8 0.3 1.3 1 0 0 1 1 1 1 Primosomal replication protein priB and priC Baculo_PEP_C PF04513.7 KEG11405.1 - 0.011 15.6 1.3 0.052 13.3 0.1 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Bacillus_HBL PF05791.6 KEG11405.1 - 0.011 15.1 1.7 0.05 12.9 0.2 2.1 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Utp12 PF04003.7 KEG11405.1 - 0.023 14.5 3.9 2.5 8.0 0.2 2.6 1 1 1 2 2 2 0 Dip2/Utp12 Family DUF1664 PF07889.7 KEG11405.1 - 0.044 13.5 1.2 0.61 9.8 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF2968 PF11180.3 KEG11405.1 - 0.045 13.1 0.5 0.071 12.4 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) WXG100 PF06013.7 KEG11405.1 - 0.045 13.7 0.1 0.092 12.7 0.1 1.6 1 0 0 1 1 1 0 Proteins of 100 residues with WXG COG2 PF06148.6 KEG11405.1 - 0.048 13.5 1.6 0.11 12.3 1.1 1.7 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Cortex-I_coil PF09304.5 KEG11405.1 - 0.12 12.4 0.5 0.23 11.5 0.3 1.5 1 0 0 1 1 1 0 Cortexillin I, coiled coil Cor1 PF04803.7 KEG11405.1 - 0.73 9.6 4.5 0.81 9.4 0.2 2.3 2 1 1 3 3 3 0 Cor1/Xlr/Xmr conserved region PMM PF03332.8 KEG11406.1 - 8.1e-101 336.1 1.3 9.2e-101 336.0 0.9 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 KEG11406.1 - 1.3e-08 34.7 0.0 6e-08 32.5 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 KEG11406.1 - 0.00082 18.7 0.0 0.16 11.2 0.0 2.0 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase_6 PF13344.1 KEG11406.1 - 0.044 13.6 0.0 0.13 12.2 0.0 1.8 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase 2OG-FeII_Oxy_2 PF13532.1 KEG11407.1 - 2.4e-07 30.8 0.0 3.3e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KEG11407.1 - 2.9e-05 24.2 0.0 5.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Metallophos PF00149.23 KEG11408.1 - 1.9e-29 102.5 0.0 2.4e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Nucleoplasmin PF03066.10 KEG11409.1 - 0.11 12.0 10.9 0.017 14.6 4.8 1.7 2 0 0 2 2 2 0 Nucleoplasmin RIX1 PF08167.7 KEG11409.1 - 0.15 11.7 9.5 3.4 7.3 0.2 3.7 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis HEAT PF02985.17 KEG11409.1 - 1.3 9.2 10.4 17 5.8 0.0 5.2 4 0 0 4 4 4 0 HEAT repeat Spc7 PF08317.6 KEG11410.1 - 0.95 8.0 22.8 0.01 14.5 5.7 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein UPF0449 PF15136.1 KEG11410.1 - 5.3 7.3 14.8 5.2 7.3 0.3 3.7 2 1 1 3 3 3 0 Uncharacterised protein family UPF0449 KIAA1430 PF13879.1 KEG11411.1 - 3.6e-20 72.2 4.3 5.9e-20 71.5 3.0 1.4 1 0 0 1 1 1 1 KIAA1430 homologue Aa_trans PF01490.13 KEG11412.1 - 3.7e-49 167.3 35.7 4.7e-49 166.9 24.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PHO4 PF01384.15 KEG11413.1 - 2.2e-110 368.3 12.4 3.1e-110 367.8 8.6 1.2 1 0 0 1 1 1 1 Phosphate transporter family Nop14 PF04147.7 KEG11413.1 - 0.73 7.6 3.7 0.9 7.3 2.6 1.0 1 0 0 1 1 1 0 Nop14-like family IncA PF04156.9 KEG11413.1 - 2.1 7.9 0.0 2.1 7.9 0.0 3.0 5 0 0 5 5 5 0 IncA protein HAMP PF00672.20 KEG11413.1 - 2.9 8.1 0.0 2.9 8.1 0.0 4.2 4 0 0 4 4 4 0 HAMP domain DOT1 PF08123.8 KEG11415.1 - 2.3e-22 79.3 0.0 2.9e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 KEG11415.1 - 9.9e-07 29.3 0.0 1.3e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEG11415.1 - 1.2e-06 28.4 0.0 1.7e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEG11415.1 - 1.3e-05 24.8 0.0 1.8e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEG11415.1 - 0.0002 21.8 0.1 0.00082 19.8 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEG11415.1 - 0.00035 20.8 0.0 0.00067 19.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KEG11415.1 - 0.00083 19.0 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.8 KEG11415.1 - 0.012 15.7 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase CMAS PF02353.15 KEG11415.1 - 0.017 14.2 0.0 0.023 13.7 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.9 KEG11415.1 - 0.026 13.8 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.12 KEG11415.1 - 0.06 12.3 0.0 0.087 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_12 PF08242.7 KEG11415.1 - 0.061 13.7 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 KEG11415.1 - 0.065 12.6 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_23 PF13489.1 KEG11415.1 - 0.085 12.5 0.0 0.13 12.0 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 KEG11415.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 WD40 PF00400.27 KEG11416.1 - 1.9e-17 62.3 12.9 1.1e-08 34.5 0.0 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat CPSF_A PF03178.10 KEG11416.1 - 0.064 12.3 0.0 0.13 11.2 0.0 1.5 1 0 0 1 1 1 0 CPSF A subunit region PQQ_3 PF13570.1 KEG11416.1 - 1 9.7 3.3 2 8.8 0.0 3.0 4 0 0 4 4 4 0 PQQ-like domain VPS9 PF02204.13 KEG11417.1 - 1.9e-05 24.6 0.1 3.4e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain RNA_pol_Rpb2_6 PF00562.23 KEG11418.1 - 1.6e-113 379.3 0.0 2.3e-113 378.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KEG11418.1 - 8.4e-45 152.1 0.2 1.3e-44 151.5 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 KEG11418.1 - 7.9e-28 96.5 0.0 1.9e-27 95.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 KEG11418.1 - 7.1e-20 71.2 0.8 2.7e-19 69.3 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 KEG11418.1 - 7.8e-20 70.4 1.3 2.7e-19 68.7 0.9 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 KEG11418.1 - 2.2e-19 68.9 0.0 4.2e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 KEG11418.1 - 5.6e-10 39.0 0.7 1.4e-09 37.7 0.5 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Glyco_tranf_2_3 PF13641.1 KEG11420.1 - 9e-08 32.1 0.0 2.4e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KEG11420.1 - 1.3e-07 31.5 0.0 2.9e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.1 KEG11420.1 - 0.0091 15.7 0.3 0.019 14.7 0.2 1.6 1 0 0 1 1 1 1 Glycosyl transferase family group 2 eIF-5a PF01287.15 KEG11425.1 - 4.7e-25 87.3 0.1 7.2e-25 86.7 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.7 KEG11425.1 - 7e-05 22.6 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain SNF2_N PF00176.18 KEG11426.1 - 2.5e-61 207.1 0.0 8.6e-36 123.2 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 KEG11426.1 - 3.2e-13 49.3 0.0 7.7e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 KEG11426.1 - 8.8e-08 31.8 4.8 8.8e-08 31.8 3.4 3.3 4 0 0 4 4 3 1 Ring finger domain zf-C3HC4 PF00097.20 KEG11426.1 - 1.7e-05 24.3 4.5 1.7e-05 24.3 3.1 2.7 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KEG11426.1 - 0.00014 21.5 2.0 0.00061 19.4 1.4 2.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 KEG11426.1 - 0.00019 21.3 5.2 0.00019 21.3 3.6 3.4 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KEG11426.1 - 0.00032 20.7 1.5 0.00032 20.7 1.1 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KEG11426.1 - 0.00086 18.9 2.4 0.00086 18.9 1.7 3.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KEG11426.1 - 0.0011 18.7 5.1 0.0015 18.3 1.2 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger ResIII PF04851.10 KEG11426.1 - 0.0017 18.2 0.0 0.42 10.4 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.1 KEG11426.1 - 0.0022 17.6 4.9 0.0022 17.6 3.4 3.2 4 0 0 4 4 3 1 zinc-RING finger domain PHD PF00628.24 KEG11426.1 - 0.0045 16.6 2.7 0.0045 16.6 1.9 2.9 3 0 0 3 3 2 1 PHD-finger Helicase_C_4 PF13871.1 KEG11426.1 - 0.047 13.1 0.0 0.088 12.2 0.0 1.4 1 0 0 1 1 1 0 Helicase_C-like FYDLN_acid PF09538.5 KEG11426.1 - 0.05 14.1 0.1 0.05 14.1 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (FYDLN_acid) RINGv PF12906.2 KEG11426.1 - 0.099 12.7 2.4 0.3 11.1 1.7 1.9 1 0 0 1 1 1 0 RING-variant domain CpXC PF14353.1 KEG11426.1 - 0.37 10.7 2.9 7.5 6.5 0.0 3.5 4 0 0 4 4 4 0 CpXC protein zf-RING_4 PF14570.1 KEG11426.1 - 0.38 10.3 10.7 3 7.4 2.0 3.5 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain Eapp_C PF10238.4 KEG11426.1 - 0.38 10.6 3.9 0.55 10.1 0.0 2.5 2 1 0 2 2 2 0 E2F-associated phosphoprotein zf-C3HC4_4 PF15227.1 KEG11426.1 - 0.43 10.4 13.3 0.059 13.2 4.0 3.1 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 KEG11426.1 - 2.1 8.3 6.4 3.1 7.8 0.5 3.2 3 0 0 3 3 3 0 FANCL C-terminal domain zinc_ribbon_4 PF13717.1 KEG11426.1 - 9.1 6.0 7.8 24 4.6 0.2 3.9 4 0 0 4 4 4 0 zinc-ribbon domain PP2C PF00481.16 KEG11427.1 - 2.9e-54 184.1 0.4 4.3e-54 183.5 0.3 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Skp1 PF01466.14 KEG11428.1 - 5.3e-08 32.7 0.4 1.1e-07 31.7 0.3 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain PABP PF00658.13 KEG11428.1 - 0.12 12.0 1.4 0.54 9.9 1.0 2.2 1 1 0 1 1 1 0 Poly-adenylate binding protein, unique domain Cyclin_N PF00134.18 KEG11429.1 - 3.1e-10 39.6 0.0 5.3e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pkinase PF00069.20 KEG11430.1 - 1e-46 159.2 0.4 2.4e-39 135.0 0.0 3.4 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEG11430.1 - 6.4e-17 61.4 0.1 8.2e-09 34.8 0.1 3.6 4 0 0 4 4 4 2 Protein tyrosine kinase Kinase-like PF14531.1 KEG11430.1 - 0.0011 18.0 0.0 0.58 9.0 0.0 2.8 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.9 KEG11430.1 - 0.011 14.7 0.2 0.02 13.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MecA PF05389.7 KEG11430.1 - 0.057 12.9 1.6 0.49 9.9 1.1 2.0 1 1 0 1 1 1 0 Negative regulator of genetic competence (MecA) RseA_C PF03873.8 KEG11430.1 - 0.32 10.9 12.9 2.7 7.9 2.4 3.5 3 0 0 3 3 3 0 Anti sigma-E protein RseA, C-terminal domain Prefoldin_2 PF01920.15 KEG11431.1 - 1.4e-11 44.0 2.7 1.7e-11 43.7 1.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit PHY PF00360.15 KEG11431.1 - 0.01 14.9 0.0 0.012 14.8 0.0 1.1 1 0 0 1 1 1 0 Phytochrome region R3H-assoc PF13902.1 KEG11431.1 - 0.024 14.6 0.2 0.029 14.3 0.1 1.2 1 0 0 1 1 1 0 R3H-associated N-terminal domain Prefoldin PF02996.12 KEG11431.1 - 0.17 11.5 8.5 0.46 10.1 2.1 2.3 1 1 1 2 2 2 0 Prefoldin subunit DUF904 PF06005.7 KEG11431.1 - 0.3 11.3 4.8 0.42 10.9 3.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF2890 PF11081.3 KEG11431.1 - 0.31 11.0 3.2 0.4 10.7 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF2681 PF10883.3 KEG11431.1 - 0.42 10.8 3.8 0.54 10.4 2.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) TPR_8 PF13181.1 KEG11432.1 - 0.00024 20.6 0.4 0.0088 15.7 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEG11432.1 - 0.00043 19.9 3.2 0.049 13.5 0.7 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KEG11432.1 - 0.0015 18.1 1.2 0.21 11.2 0.5 2.5 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KEG11432.1 - 0.024 14.2 0.7 0.058 13.0 0.5 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat PIP5K PF01504.13 KEG11433.1 - 5.8e-63 212.3 0.0 8.2e-63 211.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Pkinase PF00069.20 KEG11434.1 - 2.4e-28 98.9 0.0 1.5e-27 96.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG11434.1 - 4.5e-11 42.3 0.0 8.4e-10 38.1 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase UDPG_MGDP_dh_N PF03721.9 KEG11435.1 - 6.3e-48 162.5 0.1 1e-47 161.8 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 KEG11435.1 - 1.4e-34 118.4 0.0 1.7e-33 114.9 0.0 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 KEG11435.1 - 1e-30 105.7 0.0 2.4e-30 104.5 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain Saccharop_dh PF03435.13 KEG11435.1 - 0.057 12.3 0.0 0.088 11.7 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase VRR_NUC PF08774.6 KEG11436.1 - 2.4e-16 59.5 0.0 6.6e-16 58.1 0.0 1.8 1 0 0 1 1 1 1 VRR-NUC domain DUF1729 PF08354.5 KEG11436.1 - 0.039 13.7 0.1 0.086 12.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) Mur_ligase_M PF08245.7 KEG11437.1 - 6.2e-10 39.4 0.1 1.9e-09 37.8 0.1 1.7 1 1 0 1 1 1 1 Mur ligase middle domain RCC1_2 PF13540.1 KEG11438.1 - 4.3e-21 73.9 10.3 1.9e-08 33.6 0.0 4.4 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 KEG11438.1 - 8.3e-20 70.7 16.0 1.8e-06 28.0 3.2 5.2 4 1 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat Ax_dynein_light PF10211.4 KEG11439.1 - 1.1 9.0 8.5 0.92 9.3 2.6 2.5 1 1 1 2 2 2 0 Axonemal dynein light chain DUF904 PF06005.7 KEG11439.1 - 3.6 7.9 10.6 3.6 7.9 2.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Proteasome PF00227.21 KEG11441.1 - 1.3e-31 109.3 0.0 1.6e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit PI3_PI4_kinase PF00454.22 KEG11442.1 - 1.6e-48 165.2 0.2 6.1e-48 163.3 0.0 2.1 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 KEG11442.1 - 1.4e-42 145.9 2.1 4.2e-42 144.3 1.4 1.9 1 1 0 1 1 1 1 FAT domain Rapamycin_bind PF08771.6 KEG11442.1 - 1.2e-32 111.9 0.4 9.3e-32 109.0 0.3 2.7 1 0 0 1 1 1 1 Rapamycin binding domain DUF3385 PF11865.3 KEG11442.1 - 1.8e-22 80.0 1.7 1.8e-20 73.4 0.0 4.4 6 0 0 6 6 6 1 Domain of unknown function (DUF3385) FATC PF02260.15 KEG11442.1 - 1.1e-09 37.5 0.3 3.3e-09 36.0 0.2 1.9 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 KEG11442.1 - 7.1e-06 25.6 11.3 2.2 8.5 0.0 7.1 8 1 0 8 8 8 3 HEAT repeat Vac14_Fab1_bd PF12755.2 KEG11442.1 - 0.044 14.1 0.0 0.66 10.4 0.0 3.0 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region TPR_14 PF13428.1 KEG11442.1 - 0.24 12.1 3.0 2.7 8.8 0.1 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 KEG11442.1 - 0.34 10.5 3.2 0.42 10.3 0.4 2.7 3 0 0 3 3 3 0 TPR repeat Rcd1 PF04078.8 KEG11444.1 - 4.2e-108 360.1 0.1 4.8e-108 359.9 0.1 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like SPO22 PF08631.5 KEG11444.1 - 0.083 11.9 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like V-ATPase_H_N PF03224.9 KEG11444.1 - 0.09 11.8 0.1 0.85 8.6 0.0 2.0 1 1 0 2 2 2 0 V-ATPase subunit H RRM_1 PF00076.17 KEG11445.1 - 2e-30 104.1 0.0 5.3e-14 51.6 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG11445.1 - 7.7e-27 93.0 0.0 3e-11 43.1 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG11445.1 - 2.1e-12 46.6 0.1 4.1e-05 23.3 0.0 3.5 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 KEG11445.1 - 4.5e-07 29.7 0.0 0.0016 18.4 0.0 2.7 3 0 0 3 3 3 2 RNA binding domain Nup35_RRM_2 PF14605.1 KEG11445.1 - 1.2e-05 25.0 0.0 0.00098 18.8 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 KEG11445.1 - 0.0018 17.9 0.0 1.1 9.0 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KEG11445.1 - 0.0021 17.9 0.3 2 8.3 0.2 2.8 2 1 0 2 2 2 2 RNA binding motif YqhR PF11085.3 KEG11446.1 - 1.4 8.4 15.5 0.18 11.3 6.0 1.9 1 1 1 2 2 2 0 Conserved membrane protein YqhR Oxidored_q3 PF00499.15 KEG11446.1 - 1.5 8.5 20.9 0.074 12.8 9.2 2.0 1 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Pox_P21 PF05313.7 KEG11446.1 - 3.8 6.7 8.9 4.9 6.3 6.2 1.1 1 0 0 1 1 1 0 Poxvirus P21 membrane protein WD40 PF00400.27 KEG11447.1 - 1.1e-10 40.9 3.8 0.0007 19.3 0.0 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat Myb_DNA-bind_3 PF12776.2 KEG11448.1 - 0.0016 19.0 0.2 0.0055 17.3 0.0 1.9 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 KEG11448.1 - 0.021 14.6 0.1 0.11 12.3 0.0 2.3 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain ARD PF03079.9 KEG11449.1 - 1.7e-27 96.3 0.5 1.7e-27 96.3 0.4 2.2 2 0 0 2 2 2 1 ARD/ARD' family Cupin_2 PF07883.6 KEG11449.1 - 3.5e-05 23.2 0.0 6.3e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 KEG11449.1 - 0.00025 20.7 0.0 0.00043 19.9 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain PhyH PF05721.8 KEG11449.1 - 0.11 12.5 0.9 1.7 8.6 0.0 2.3 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) YqfQ PF14181.1 KEG11449.1 - 0.96 9.4 4.1 1.5 8.8 2.8 1.4 1 0 0 1 1 1 0 YqfQ-like protein CDC45 PF02724.9 KEG11449.1 - 1.8 6.5 9.5 2.2 6.2 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.7 KEG11449.1 - 8.3 6.2 9.8 15 5.3 6.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3105 PF11303.3 KEG11450.1 - 0.15 11.8 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3105) cNMP_binding PF00027.24 KEG11452.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain DUF3735 PF12537.3 KEG11453.1 - 0.032 14.2 0.0 0.065 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3735) Macoilin PF09726.4 KEG11454.1 - 0.61 8.2 7.9 0.79 7.9 5.5 1.1 1 0 0 1 1 1 0 Transmembrane protein IF4E PF01652.13 KEG11456.1 - 1.5e-54 183.9 0.2 3.4e-54 182.7 0.1 1.5 1 1 0 1 1 1 1 Eukaryotic initiation factor 4E DUF3682 PF12446.3 KEG11456.1 - 0.00095 19.4 9.5 0.00095 19.4 6.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3682) WD40 PF00400.27 KEG11457.1 - 4e-12 45.5 6.6 0.00021 21.0 0.3 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat eIF2A PF08662.6 KEG11457.1 - 0.17 11.5 0.0 18 4.9 0.0 3.0 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A BRO1 PF03097.13 KEG11458.1 - 1.2e-66 224.9 0.1 5.7e-66 222.7 0.0 2.1 2 1 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 KEG11458.1 - 1.4e-46 158.8 3.5 1.4e-46 158.8 2.4 2.7 3 0 0 3 3 3 1 ALIX V-shaped domain binding to HIV WWbp PF10349.4 KEG11458.1 - 0.41 11.5 10.5 0.97 10.3 7.3 1.7 1 0 0 1 1 1 0 WW-domain ligand protein Helicase_IV_N PF12462.3 KEG11459.1 - 0.0013 18.4 0.0 0.0027 17.3 0.0 1.4 1 0 0 1 1 1 1 DNA helicase IV / RNA helicase N terminal HABP4_PAI-RBP1 PF04774.10 KEG11459.1 - 0.13 12.8 5.3 0.68 10.4 0.1 2.5 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family FlxA PF14282.1 KEG11460.1 - 2.6 8.0 5.0 2.9 7.8 2.2 2.0 2 0 0 2 2 2 0 FlxA-like protein ABC_tran PF00005.22 KEG11461.1 - 1.5e-05 25.3 0.1 2.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 KEG11461.1 - 0.00085 18.5 20.6 0.00085 18.5 14.3 1.6 2 0 0 2 2 2 1 ABC-2 type transporter MRAP PF15183.1 KEG11461.1 - 0.061 12.9 0.7 0.17 11.5 0.5 1.7 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family G6PD_C PF02781.11 KEG11462.1 - 3.4e-113 377.3 0.0 4.4e-113 377.0 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 KEG11462.1 - 1.8e-60 204.3 0.0 2.8e-60 203.6 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain peroxidase PF00141.18 KEG11463.1 - 3.9e-45 154.1 0.0 8e-45 153.0 0.0 1.5 1 1 0 1 1 1 1 Peroxidase CLPTM1 PF05602.7 KEG11466.1 - 1.3e-110 370.1 0.3 2e-110 369.5 0.2 1.2 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) DnaJ PF00226.26 KEG11467.1 - 1.7e-14 53.2 0.0 3.6e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Pkinase PF00069.20 KEG11468.1 - 5.9e-41 140.3 0.0 7.5e-41 139.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG11468.1 - 5.6e-24 84.6 0.0 6.7e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG11468.1 - 3.7e-05 22.8 0.0 0.00031 19.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like CCAP PF11105.3 KEG11469.1 - 0.11 12.2 0.2 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a Rsm22 PF09243.5 KEG11472.1 - 1.6e-28 99.5 2.4 5.2e-17 61.7 0.2 3.3 3 0 0 3 3 3 2 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_18 PF12847.2 KEG11472.1 - 0.0015 19.0 0.8 0.6 10.7 0.0 3.1 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 KEG11472.1 - 0.075 13.5 0.0 4.4 7.8 0.0 2.8 2 0 0 2 2 2 0 Methyltransferase domain Phosphodiest PF01663.17 KEG11473.1 - 1.6e-06 27.6 0.2 3.3e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF917 PF06032.7 KEG11473.1 - 0.031 12.8 0.0 0.052 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF917) DUF98 PF01947.11 KEG11474.1 - 0.15 11.7 0.0 20 4.9 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF98) Aminotran_1_2 PF00155.16 KEG11475.1 - 2.3e-72 243.9 0.0 2.7e-72 243.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II TPR_11 PF13414.1 KEG11479.1 - 2.4e-09 36.7 0.5 1.2e-07 31.2 0.0 2.2 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 KEG11479.1 - 3.4e-05 23.4 0.0 0.27 11.2 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat SET PF00856.23 KEG11479.1 - 8.8e-05 22.8 0.4 0.001 19.4 0.3 2.3 1 1 0 1 1 1 1 SET domain TPR_1 PF00515.23 KEG11479.1 - 0.0031 17.0 0.0 0.53 9.9 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KEG11479.1 - 0.0032 17.9 0.1 0.22 12.2 0.0 3.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KEG11479.1 - 0.0043 16.9 0.1 0.027 14.3 0.1 2.3 1 1 0 1 1 1 1 Tetratricopeptide repeat Actin PF00022.14 KEG11480.1 - 2.4e-89 299.4 0.0 2.8e-89 299.2 0.0 1.0 1 0 0 1 1 1 1 Actin AAA_16 PF13191.1 KEG11482.1 - 3.6e-06 27.0 0.2 4e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain SR-25 PF10500.4 KEG11482.1 - 0.0033 16.9 0.9 0.0036 16.7 0.6 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein AAA_22 PF13401.1 KEG11482.1 - 0.012 15.7 0.2 0.14 12.3 0.1 2.1 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 KEG11482.1 - 0.026 14.0 0.3 0.042 13.3 0.2 1.4 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Arch_ATPase PF01637.13 KEG11482.1 - 0.037 13.7 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Med3 PF11593.3 KEG11482.1 - 0.068 12.3 1.6 0.07 12.3 1.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Miro PF08477.8 KEG11482.1 - 0.089 13.2 0.0 0.12 12.9 0.0 1.3 1 0 0 1 1 1 0 Miro-like protein SUZ PF12752.2 KEG11482.1 - 1.2 9.7 7.2 0.24 11.9 0.6 2.6 2 1 1 3 3 3 0 SUZ domain TraV PF09676.5 KEG11482.1 - 7.1 7.3 8.7 3.2 8.4 4.5 1.4 1 1 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) DUF3288 PF11691.3 KEG11485.1 - 0.027 14.1 0.0 3.1 7.5 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3288) DUF3557 PF12078.3 KEG11485.1 - 0.12 12.0 0.0 6.2 6.5 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3557) PetM PF08041.6 KEG11485.1 - 4.5 6.8 5.9 52 3.4 0.0 3.5 3 1 1 4 4 4 0 PetM family of cytochrome b6f complex subunit 7 Arf PF00025.16 KEG11486.1 - 1.2e-21 76.7 0.8 6.7e-07 28.7 0.0 4.7 5 0 0 5 5 5 4 ADP-ribosylation factor family G-alpha PF00503.15 KEG11486.1 - 4.5e-08 32.1 0.0 0.0031 16.2 0.0 3.1 3 0 0 3 3 3 2 G-protein alpha subunit SRPRB PF09439.5 KEG11486.1 - 0.0012 18.0 0.1 0.05 12.8 0.0 2.3 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 KEG11486.1 - 0.0046 16.4 0.1 2 7.8 0.0 2.4 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain Miro PF08477.8 KEG11486.1 - 0.0097 16.3 0.0 0.47 10.9 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein AAA_28 PF13521.1 KEG11486.1 - 0.021 14.8 0.3 0.021 14.8 0.2 1.5 2 0 0 2 2 2 0 AAA domain MAP65_ASE1 PF03999.7 KEG11489.1 - 2 6.8 4.2 3.1 6.2 2.9 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Acetyltransf_1 PF00583.19 KEG11493.1 - 0.0035 17.3 0.1 0.01 15.8 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEG11493.1 - 0.011 15.8 0.0 0.072 13.2 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KEG11493.1 - 0.094 12.5 0.1 0.41 10.5 0.1 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Phos_pyr_kin PF08543.7 KEG11494.1 - 1.4e-14 53.9 0.0 1.8e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 KEG11494.1 - 1.1e-09 37.8 1.2 3.3e-08 33.0 0.8 2.7 1 1 0 1 1 1 1 pfkB family carbohydrate kinase FYVE_2 PF02318.11 KEG11495.1 - 0.0019 18.1 8.0 0.004 17.0 5.5 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger FYVE PF01363.16 KEG11495.1 - 0.035 13.9 13.8 0.071 13.0 9.6 1.5 1 0 0 1 1 1 0 FYVE zinc finger EF-hand_7 PF13499.1 KEG11497.1 - 0.00038 20.5 0.2 0.0058 16.7 0.1 2.6 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KEG11497.1 - 0.0026 16.9 0.2 0.044 13.1 0.0 2.7 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 KEG11497.1 - 0.0033 17.1 0.0 0.019 14.7 0.0 2.4 1 0 0 1 1 1 1 EF-hand domain zf-C3HC4_3 PF13920.1 KEG11498.1 - 7.3e-06 25.5 8.8 7.3e-06 25.5 6.1 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEG11498.1 - 0.0018 18.2 12.3 0.0018 18.2 8.5 3.6 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEG11498.1 - 0.0074 16.0 12.0 0.0074 16.0 8.3 3.5 2 1 0 2 2 2 1 Ring finger domain zf-RING_4 PF14570.1 KEG11498.1 - 5.5 6.6 13.6 1.7 8.2 6.3 2.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain AAA_28 PF13521.1 KEG11499.1 - 8.5e-24 84.3 0.0 1.4e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEG11499.1 - 0.00016 22.5 0.0 0.00037 21.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KEG11499.1 - 0.0017 17.6 0.0 0.0029 16.8 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 ArgK PF03308.11 KEG11499.1 - 0.0033 16.2 0.0 0.0057 15.4 0.0 1.3 1 0 0 1 1 1 1 ArgK protein AAA_18 PF13238.1 KEG11499.1 - 0.021 15.1 0.0 0.043 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.4 KEG11499.1 - 0.076 11.9 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 LSM PF01423.17 KEG11500.1 - 1.9e-14 52.9 0.0 2.4e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain UCH PF00443.24 KEG11501.1 - 4.2e-42 144.1 0.0 5.6e-42 143.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEG11501.1 - 1.1e-16 61.1 0.0 7.2e-16 58.4 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TMEM107 PF14995.1 KEG11502.1 - 1.2e-30 106.1 8.0 1.4e-30 105.9 5.5 1.1 1 0 0 1 1 1 1 Transmembrane protein DUF3359 PF11839.3 KEG11504.1 - 7 7.0 10.2 14 6.0 7.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3359) Tautomerase PF01361.16 KEG11505.1 - 0.0018 17.8 0.3 0.033 13.7 0.0 2.8 2 0 0 2 2 2 1 Tautomerase enzyme Tropomyosin PF00261.15 KEG11505.1 - 0.71 8.9 35.6 0.98 8.4 24.6 1.1 1 0 0 1 1 1 0 Tropomyosin Herpes_UL87 PF03043.9 KEG11505.1 - 2.6 6.3 8.3 3.3 5.9 5.8 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family PIN_4 PF13638.1 KEG11505.1 - 3.9 7.5 11.6 12 5.9 0.3 2.2 2 0 0 2 2 2 0 PIN domain GAS PF13851.1 KEG11505.1 - 7.1 5.7 22.8 0.84 8.7 6.4 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding LSM PF01423.17 KEG11507.1 - 7.7e-06 25.3 0.0 1.2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 LSM domain DNA_ligase_ZBD PF03119.11 KEG11507.1 - 0.15 11.8 1.1 0.87 9.3 0.0 2.5 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain Cullin PF00888.17 KEG11509.1 - 4.4e-41 141.1 0.0 2.3e-35 122.2 0.0 3.0 3 0 0 3 3 3 2 Cullin family Cullin_Nedd8 PF10557.4 KEG11509.1 - 6e-20 70.8 0.0 1.2e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Cullin protein neddylation domain GMC_oxred_N PF00732.14 KEG11513.1 - 5.6e-17 61.8 0.0 7.5e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEG11513.1 - 6e-07 29.8 0.0 0.00011 22.4 0.0 2.4 1 1 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KEG11513.1 - 1.9e-06 27.0 2.5 1.2e-05 24.4 1.7 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEG11513.1 - 0.00012 21.1 0.6 0.14 10.9 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KEG11513.1 - 0.0013 17.6 0.1 0.018 13.9 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.9 KEG11513.1 - 0.0017 16.9 0.3 0.2 10.0 0.1 2.3 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_3 PF01494.14 KEG11513.1 - 0.0036 16.4 0.9 0.041 12.9 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KEG11513.1 - 0.0062 16.5 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KEG11513.1 - 0.02 14.7 0.1 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEG11513.1 - 0.043 13.6 0.3 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KEG11513.1 - 0.075 13.0 0.0 13 5.7 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.20 KEG11514.1 - 2.7e-66 223.4 0.0 2.7e-66 223.4 0.0 2.2 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG11514.1 - 1.2e-42 145.8 1.1 1.4e-42 145.5 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG11514.1 - 3.7e-06 26.1 0.0 8.6e-06 24.9 0.0 1.6 1 0 0 1 1 1 1 Kinase-like MIP-T3 PF10243.4 KEG11515.1 - 1.7e-100 337.0 74.7 1.7e-99 333.7 51.8 1.9 1 1 0 1 1 1 1 Microtubule-binding protein MIP-T3 DUF4551 PF15087.1 KEG11515.1 - 6.5 4.9 22.7 13 4.0 15.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) peroxidase PF00141.18 KEG11517.1 - 5.4e-07 29.3 0.0 1e-06 28.3 0.0 1.5 1 1 0 1 1 1 1 Peroxidase QRPTase_N PF02749.11 KEG11517.1 - 0.096 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain WD40 PF00400.27 KEG11518.1 - 5.1e-06 26.1 4.5 0.0037 17.0 0.1 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat HBS1_N PF08938.5 KEG11519.1 - 0.21 11.7 3.3 0.48 10.5 0.2 2.7 3 0 0 3 3 3 0 HBS1 N-terminus F-box-like PF12937.2 KEG11520.1 - 7.4e-06 25.6 0.1 1.6e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 F-box-like DUF3500 PF12006.3 KEG11520.1 - 0.082 11.8 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3500) zf-ribbon_3 PF13248.1 KEG11521.1 - 0.028 13.6 1.4 0.39 9.9 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DUF4109 PF13397.1 KEG11521.1 - 0.083 13.2 0.5 8.7 6.7 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4109) DZR PF12773.2 KEG11521.1 - 0.19 11.5 2.0 0.46 10.3 1.4 1.7 1 1 0 1 1 1 0 Double zinc ribbon Terminase_GpA PF05876.7 KEG11521.1 - 0.22 9.8 2.1 0.33 9.2 0.5 1.7 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) zinc_ribbon_5 PF13719.1 KEG11521.1 - 0.22 11.1 2.3 0.72 9.4 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Rubredoxin PF00301.15 KEG11521.1 - 0.22 11.4 0.7 0.22 11.4 0.5 2.8 3 0 0 3 3 3 0 Rubredoxin Lar_restr_allev PF14354.1 KEG11521.1 - 0.32 11.3 2.2 0.86 9.9 1.5 1.8 1 1 0 1 1 1 0 Restriction alleviation protein Lar zf-ISL3 PF14690.1 KEG11521.1 - 0.33 11.0 1.9 0.67 10.0 0.1 2.2 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn-ribbon_8 PF09723.5 KEG11521.1 - 1.5 8.8 5.2 6.3 6.8 0.3 2.6 1 1 2 3 3 3 0 Zinc ribbon domain zf-RanBP PF00641.13 KEG11521.1 - 1.7 7.8 5.6 0.23 10.6 0.5 2.0 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Rad60-SLD_2 PF13881.1 KEG11522.1 - 4.3e-05 23.3 0.1 0.0002 21.2 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KEG11522.1 - 0.00016 21.8 0.0 0.00021 21.4 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain PPR_2 PF13041.1 KEG11523.1 - 2.5e-06 27.3 0.0 4.8e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 PPR repeat family PPR PF01535.15 KEG11523.1 - 0.0085 16.0 0.0 0.03 14.2 0.0 2.0 1 0 0 1 1 1 1 PPR repeat PPR_3 PF13812.1 KEG11523.1 - 0.013 15.6 0.4 0.08 13.2 0.0 2.7 4 0 0 4 4 4 0 Pentatricopeptide repeat domain ApbE PF02424.10 KEG11524.1 - 4.5e-59 199.8 0.0 8.5e-59 198.8 0.0 1.4 2 0 0 2 2 2 1 ApbE family FAD_binding_2 PF00890.19 KEG11524.1 - 3e-07 29.6 4.0 5.7e-07 28.7 2.8 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KEG11524.1 - 8.9e-06 25.0 3.3 1.5e-05 24.2 2.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KEG11524.1 - 1.4e-05 24.1 2.5 1.4e-05 24.1 1.7 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 KEG11524.1 - 5.3e-05 23.1 1.0 0.00011 22.1 0.7 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEG11524.1 - 0.00037 19.5 1.5 0.00066 18.6 1.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KEG11524.1 - 0.0012 17.3 2.1 0.0018 16.8 1.5 1.2 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.16 KEG11524.1 - 0.0015 18.1 0.3 0.0025 17.4 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 KEG11524.1 - 0.006 15.6 0.5 0.0088 15.1 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KEG11524.1 - 0.034 14.5 1.3 0.075 13.4 0.9 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEG11524.1 - 0.044 13.7 1.1 0.17 11.9 0.8 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KEG11524.1 - 0.12 11.5 0.1 0.18 10.8 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Rhodanese PF00581.15 KEG11525.1 - 4.1e-11 43.2 0.0 1.1e-10 41.8 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain STT3 PF02516.9 KEG11526.1 - 2.1e-53 181.9 30.2 1.4e-51 176.0 20.9 2.2 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit ATP-synt_J PF04911.7 KEG11526.1 - 0.15 11.4 1.0 0.89 9.0 0.0 2.7 3 0 0 3 3 3 0 ATP synthase j chain Rdx PF10262.4 KEG11527.1 - 2.4e-08 33.8 0.0 2.4e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Rdx family SAP PF02037.22 KEG11528.1 - 0.074 12.5 3.1 0.34 10.4 0.1 2.7 3 0 0 3 3 3 0 SAP domain Njmu-R1 PF15053.1 KEG11528.1 - 0.077 11.7 0.1 0.081 11.6 0.0 1.1 1 0 0 1 1 1 0 Mjmu-R1-like protein family TMEM125 PF15109.1 KEG11528.1 - 0.11 12.5 0.9 0.14 12.3 0.3 1.4 2 0 0 2 2 2 0 TMEM125 protein family HeH PF12949.2 KEG11528.1 - 0.22 11.0 1.3 1.6 8.3 0.1 2.5 3 0 0 3 3 3 0 HeH/LEM domain VASP_tetra PF08776.6 KEG11528.1 - 0.36 10.1 2.2 8.8 5.7 0.5 2.5 1 1 1 2 2 2 0 VASP tetramerisation domain Kri1_C PF12936.2 KEG11530.1 - 1e-23 83.0 0.1 1e-23 83.0 0.0 3.5 3 0 0 3 3 3 1 KRI1-like family C-terminal Kri1 PF05178.7 KEG11530.1 - 1.5e-20 73.3 21.5 1.5e-20 73.3 14.9 5.2 4 2 0 4 4 4 1 KRI1-like family DUF3537 PF12056.3 KEG11530.1 - 0.76 8.4 1.1 1.6 7.3 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) ASD2 PF08687.6 KEG11532.1 - 0.00041 19.7 2.7 0.00058 19.2 1.8 1.2 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 RR_TM4-6 PF06459.7 KEG11532.1 - 0.37 10.6 5.4 0.57 10.0 3.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDE_Tnp_1_7 PF13843.1 KEG11532.1 - 0.55 9.2 6.1 0.78 8.7 4.2 1.1 1 0 0 1 1 1 0 Transposase IS4 SR-25 PF10500.4 KEG11532.1 - 7.8 5.9 33.6 13 5.1 22.9 1.6 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.20 KEG11533.1 - 2.6e-64 216.8 0.1 4.9e-64 215.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG11533.1 - 6.7e-22 77.7 0.6 2e-13 50.0 0.3 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KEG11533.1 - 5.3e-05 22.3 0.1 0.039 12.8 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 KEG11533.1 - 0.066 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RPN7 PF10602.4 KEG11534.1 - 2.4e-50 170.3 1.0 3.9e-50 169.6 0.1 1.7 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 KEG11534.1 - 1.5e-11 44.4 0.0 3.2e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 PCI domain SAC3_GANP PF03399.11 KEG11534.1 - 0.00019 21.0 0.1 0.00035 20.1 0.1 1.5 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KEG11534.1 - 0.003 17.3 0.0 0.006 16.3 0.0 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 FeoC PF09012.5 KEG11534.1 - 0.1 12.3 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 FeoC like transcriptional regulator DUF2786 PF10979.3 KEG11534.1 - 2.3 8.0 7.6 4.4 7.1 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2786) RRM_1 PF00076.17 KEG11535.1 - 8e-22 76.6 1.0 3.3e-09 36.2 0.0 3.8 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG11535.1 - 1.9e-18 66.2 0.6 1.4e-07 31.3 0.0 3.3 3 1 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG11535.1 - 1.8e-11 43.7 0.0 2.7e-07 30.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fic PF02661.13 KEG11539.1 - 0.07 13.8 0.4 0.28 11.9 0.2 2.0 1 0 0 1 1 1 0 Fic/DOC family Sec7 PF01369.15 KEG11540.1 - 3.4e-28 98.6 0.0 6.2e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 KEG11540.1 - 1.1e-16 60.6 0.3 2.7e-16 59.4 0.2 1.7 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Urb2 PF10441.4 KEG11540.1 - 0.35 10.4 3.2 1.6 8.2 0.1 2.5 2 0 0 2 2 2 0 Urb2/Npa2 family Apc4_WD40 PF12894.2 KEG11542.1 - 0.043 13.3 0.1 3.8 7.0 0.0 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain SelB-wing_1 PF09105.5 KEG11543.1 - 0.11 12.1 0.1 0.23 11.1 0.1 1.5 1 0 0 1 1 1 0 Elongation factor SelB, winged helix RabGAP-TBC PF00566.13 KEG11544.1 - 3.6e-08 33.1 0.2 4.2e-08 32.9 0.1 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RFC1 PF08519.7 KEG11548.1 - 1.1e-48 164.9 0.2 2.7e-48 163.6 0.0 1.8 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain Rad17 PF03215.10 KEG11548.1 - 2.6e-13 49.5 0.1 6.2e-10 38.3 0.0 2.5 2 1 1 3 3 3 2 Rad17 cell cycle checkpoint protein AAA PF00004.24 KEG11548.1 - 3.7e-12 46.5 0.0 1.4e-11 44.7 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEG11548.1 - 2.6e-05 24.3 0.0 0.00012 22.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEG11548.1 - 5e-05 23.3 0.0 0.00014 21.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 KEG11548.1 - 0.00011 22.1 0.0 0.00026 20.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KEG11548.1 - 0.0018 17.8 2.4 0.099 12.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KEG11548.1 - 0.0019 19.0 0.0 0.005 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KEG11548.1 - 0.0019 17.2 0.0 0.004 16.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 KEG11548.1 - 0.0027 17.8 0.0 0.018 15.2 0.0 2.5 2 1 0 2 2 2 1 RNA helicase AAA_5 PF07728.9 KEG11548.1 - 0.0031 17.2 0.0 0.0084 15.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KEG11548.1 - 0.0042 16.9 0.0 0.012 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEG11548.1 - 0.0059 16.3 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 KEG11548.1 - 0.016 15.5 0.0 0.044 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KEG11548.1 - 0.02 14.8 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KEG11548.1 - 0.037 13.7 0.0 0.094 12.4 0.0 1.6 1 0 0 1 1 1 0 NTPase Viral_helicase1 PF01443.13 KEG11548.1 - 0.038 13.4 0.0 0.1 12.0 0.0 1.8 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PSD4 PF07631.6 KEG11549.1 - 0.082 13.2 0.1 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1592) DUF1192 PF06698.6 KEG11550.1 - 0.29 10.9 2.5 3.1 7.6 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Mnd1 PF03962.10 KEG11551.1 - 2.4e-56 190.3 0.4 4.5e-56 189.4 0.3 1.5 1 0 0 1 1 1 1 Mnd1 family TBPIP PF07106.8 KEG11551.1 - 2.7e-07 30.3 0.1 4.4e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ATG16 PF08614.6 KEG11551.1 - 0.011 15.6 1.0 0.011 15.6 0.7 1.6 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) CHD5 PF04420.9 KEG11551.1 - 0.056 13.0 1.2 0.55 9.8 0.3 2.2 2 0 0 2 2 2 0 CHD5-like protein FlxA PF14282.1 KEG11551.1 - 0.36 10.7 8.8 0.19 11.7 2.8 2.4 2 0 0 2 2 2 0 FlxA-like protein Adeno_PIX PF03955.9 KEG11551.1 - 1.2 9.6 5.8 0.31 11.5 1.1 2.2 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) CRAL_TRIO PF00650.15 KEG11552.1 - 2.4e-13 49.8 0.1 7.3e-13 48.3 0.0 1.8 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO PF00650.15 KEG11553.1 - 2.3e-12 46.6 0.0 4.2e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain Aa_trans PF01490.13 KEG11554.1 - 1.2e-47 162.2 33.0 1.5e-47 161.9 22.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 KEG11554.1 - 2.8e-08 32.7 20.0 2.8e-08 32.7 13.9 2.1 1 1 0 2 2 2 1 Amino acid permease Trp_Tyr_perm PF03222.8 KEG11554.1 - 1.6e-07 30.4 19.4 3.4e-07 29.4 13.4 1.4 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Aa_trans PF01490.13 KEG11555.1 - 3.8e-53 180.4 31.3 4.6e-53 180.1 21.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KEG11555.1 - 1.3e-09 37.3 13.7 1.3e-09 37.3 9.5 2.0 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family DUF21 PF01595.15 KEG11555.1 - 0.036 13.3 0.1 0.036 13.3 0.1 2.4 3 1 0 3 3 3 0 Domain of unknown function DUF21 Peptidase_C2 PF00648.16 KEG11557.1 - 3.9e-40 137.7 0.0 5.4e-40 137.2 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 KEG11557.1 - 9.5e-21 73.7 0.0 1.7e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) LRR_4 PF12799.2 KEG11559.1 - 5.9e-41 137.4 2.6 0.00017 21.0 0.0 12.3 8 2 4 12 12 12 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG11559.1 - 7.8e-24 83.2 8.3 0.0028 17.3 0.0 8.7 5 3 4 10 10 10 9 Leucine rich repeat LRR_6 PF13516.1 KEG11559.1 - 8.3e-22 74.7 10.6 0.0034 17.2 0.0 12.5 14 1 0 14 14 14 5 Leucine Rich repeat LRR_1 PF00560.28 KEG11559.1 - 6.8e-11 40.6 19.8 4 7.8 0.0 15.0 17 2 0 17 17 17 1 Leucine Rich Repeat LRR_7 PF13504.1 KEG11559.1 - 0.00045 19.9 28.0 13 6.5 0.1 12.0 10 1 1 11 11 11 1 Leucine rich repeat Dynein_heavy PF03028.10 KEG11561.1 - 6e-216 718.7 0.0 1.3e-215 717.5 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 KEG11561.1 - 7.7e-110 367.1 8.5 7.7e-110 367.1 5.9 3.1 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 KEG11561.1 - 6.7e-98 326.8 0.1 2e-97 325.2 0.0 1.9 2 0 0 2 2 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 KEG11561.1 - 1.9e-65 220.5 0.0 4.3e-65 219.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 KEG11561.1 - 1.6e-50 171.1 2.2 6.2e-50 169.1 0.1 2.5 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_7 PF12775.2 KEG11561.1 - 2e-48 164.8 0.0 3.3e-48 164.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 MT PF12777.2 KEG11561.1 - 1.6e-28 99.4 13.1 1.6e-28 99.4 9.1 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 KEG11561.1 - 1.3e-19 70.3 0.0 1.2e-05 25.0 0.0 5.8 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KEG11561.1 - 5e-07 29.9 1.2 0.09 12.9 0.0 5.5 4 1 1 5 5 5 2 AAA domain AAA PF00004.24 KEG11561.1 - 3.3e-06 27.3 5.6 0.028 14.6 0.0 3.6 4 0 0 4 4 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEG11561.1 - 7.4e-05 22.8 8.7 0.021 14.8 0.0 5.8 5 1 1 6 6 6 1 AAA ATPase domain AAA_17 PF13207.1 KEG11561.1 - 0.0001 23.0 0.0 0.012 16.3 0.0 3.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KEG11561.1 - 0.00044 20.5 0.8 0.28 11.5 0.0 4.3 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.17 KEG11561.1 - 0.00051 20.1 0.2 2.5 8.3 0.0 3.7 3 0 0 3 3 3 2 RNA helicase T2SE PF00437.15 KEG11561.1 - 0.0012 17.8 1.4 0.0055 15.6 0.0 2.8 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_33 PF13671.1 KEG11561.1 - 0.0015 18.3 0.0 1.3 8.9 0.0 3.8 3 0 0 3 3 3 1 AAA domain UPF0079 PF02367.12 KEG11561.1 - 0.0021 17.7 0.2 0.52 9.9 0.0 2.9 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 KEG11561.1 - 0.057 13.1 0.8 4.3 7.1 0.0 3.2 3 0 0 3 3 2 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 KEG11561.1 - 4.3 6.7 8.1 6.9 6.0 0.0 3.3 3 0 0 3 3 3 0 FtsK/SpoIIIE family Kri1 PF05178.7 KEG11562.1 - 0.19 12.0 3.2 0.43 10.8 2.2 1.6 1 0 0 1 1 1 0 KRI1-like family eIF3_subunit PF08597.5 KEG11562.1 - 1.4 8.4 9.8 1.5 8.3 6.8 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit TTL PF03133.10 KEG11563.1 - 1.1e-56 191.9 0.0 1.5e-56 191.4 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 KEG11563.1 - 0.00019 20.3 0.0 0.31 9.8 0.0 2.4 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 KEG11563.1 - 0.00052 19.8 0.0 0.0047 16.6 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KEG11563.1 - 0.0011 18.8 0.0 0.065 13.0 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain CP_ATPgrasp_1 PF04174.8 KEG11563.1 - 0.0036 15.9 0.0 0.099 11.2 0.0 2.1 2 0 0 2 2 2 1 A circularly permuted ATPgrasp RimK PF08443.6 KEG11563.1 - 0.017 14.5 0.0 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.1 KEG11563.1 - 0.054 12.5 0.0 3.3 6.6 0.0 2.1 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Dala_Dala_lig_C PF07478.8 KEG11563.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus WD40 PF00400.27 KEG11564.1 - 7.9e-13 47.7 0.9 2.1e-06 27.4 0.1 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Spectrin PF00435.16 KEG11565.1 - 0.42 10.9 17.7 0.74 10.1 0.1 3.4 1 1 1 3 3 3 0 Spectrin repeat IncA PF04156.9 KEG11565.1 - 2.1 7.8 24.3 0.64 9.5 1.4 2.9 1 1 1 2 2 2 0 IncA protein GAS PF13851.1 KEG11565.1 - 3.2 6.8 21.3 0.3 10.2 9.6 2.2 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Phage_GP20 PF06810.6 KEG11565.1 - 4.8 6.6 16.2 4 6.8 6.1 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 IFT57 PF10498.4 KEG11565.1 - 7 5.2 19.7 1.4 7.5 9.0 2.0 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 ATP_bind_1 PF03029.12 KEG11567.1 - 7e-51 173.0 0.0 7.4e-50 169.7 0.0 2.0 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.1 KEG11567.1 - 0.005 16.7 0.1 0.015 15.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KEG11567.1 - 0.016 16.0 1.7 0.034 14.9 0.3 2.0 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 KEG11567.1 - 0.039 14.1 0.0 0.37 11.0 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEG11567.1 - 0.081 13.0 0.1 0.15 12.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KEG11567.1 - 0.32 11.2 2.2 0.34 11.2 0.2 2.0 2 0 0 2 2 2 0 AAA domain PAP_assoc PF03828.14 KEG11568.1 - 0.00068 19.5 0.0 0.002 18.0 0.0 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase LRR_6 PF13516.1 KEG11569.1 - 6e-26 87.5 32.2 0.16 12.1 0.1 13.1 13 0 0 13 13 13 10 Leucine Rich repeat LRR_4 PF12799.2 KEG11569.1 - 7.9e-08 31.7 26.1 0.0061 16.1 0.1 7.2 3 1 6 9 9 9 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEG11569.1 - 0.00016 21.2 25.3 20 5.7 0.0 10.7 10 3 3 13 13 13 2 Leucine Rich Repeat LRR_7 PF13504.1 KEG11569.1 - 0.0024 17.7 23.1 9.1 6.9 0.0 10.1 12 0 0 12 12 12 1 Leucine rich repeat LRR_8 PF13855.1 KEG11569.1 - 0.41 10.4 23.6 5.1 6.9 1.8 6.6 3 2 2 5 5 5 0 Leucine rich repeat Ank_2 PF12796.2 KEG11570.1 - 0.00011 22.4 0.0 0.0005 20.3 0.0 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KEG11570.1 - 0.00077 19.6 0.0 0.005 17.0 0.0 2.5 2 1 0 2 2 2 1 Ankyrin repeats (many copies) DNA_pol_phi PF04931.8 KEG11570.1 - 4.7 4.8 7.1 7.7 4.1 4.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF2842 PF11003.3 KEG11572.1 - 0.16 11.8 0.2 0.41 10.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2842) Complex1_LYR_1 PF13232.1 KEG11573.1 - 1.6e-05 25.0 2.0 3.9e-05 23.7 1.4 1.6 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KEG11573.1 - 0.00032 20.4 2.1 0.00032 20.4 1.4 1.9 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Clr5 PF14420.1 KEG11573.1 - 0.094 12.6 1.4 2.5 8.0 0.1 2.7 2 0 0 2 2 2 0 Clr5 domain eIF-5_eIF-2B PF01873.12 KEG11575.1 - 1.6e-23 82.7 0.6 2.7e-23 81.9 0.4 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Cytochrom_c3_2 PF14537.1 KEG11575.1 - 0.15 12.3 2.0 0.4 11.0 0.2 2.4 3 0 0 3 3 3 0 Cytochrome c3 Img2 PF05046.9 KEG11576.1 - 0.0065 16.6 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Mito_fiss_reg PF05308.6 KEG11576.1 - 7.6 5.8 6.9 11 5.2 4.8 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator TMEM52 PF14979.1 KEG11577.1 - 0.05 13.5 0.0 0.062 13.1 0.0 1.1 1 0 0 1 1 1 0 Transmembrane 52 DUF1049 PF06305.6 KEG11577.1 - 0.078 12.4 0.7 0.13 11.7 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) UPF0139 PF03669.8 KEG11578.1 - 0.087 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0139) OAD_gamma PF04277.8 KEG11578.1 - 4.5 7.7 6.6 3.8 7.9 3.3 1.7 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain SSDP PF04503.8 KEG11579.1 - 0.083 12.6 1.0 0.095 12.4 0.7 1.0 1 0 0 1 1 1 0 Single-stranded DNA binding protein, SSDP FLO_LFY PF01698.11 KEG11580.1 - 0.0046 15.8 9.0 0.0046 15.8 6.3 2.1 2 0 0 2 2 2 1 Floricaula / Leafy protein SID-1_RNA_chan PF13965.1 KEG11580.1 - 2.2 6.3 4.8 4.2 5.4 3.3 1.4 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Zip PF02535.17 KEG11580.1 - 2.8 6.8 4.0 0.81 8.6 0.6 1.6 2 0 0 2 2 2 0 ZIP Zinc transporter Amdo_NSP PF12475.3 KEG11580.1 - 6.7 6.7 5.4 33 4.4 0.2 2.7 2 0 0 2 2 2 0 Amdovirus non-structural protein Peptidase_M8 PF01457.11 KEG11581.1 - 1.7e-106 356.6 0.4 2.2e-106 356.2 0.3 1.0 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M10 PF00413.19 KEG11581.1 - 0.091 12.4 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Matrixin Nop53 PF07767.6 KEG11582.1 - 0.027 13.4 11.8 0.029 13.3 8.2 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Tom37_C PF11801.3 KEG11582.1 - 0.086 12.7 1.4 0.12 12.2 1.0 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain CENP-T PF15511.1 KEG11582.1 - 0.51 9.5 7.4 0.65 9.1 5.1 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Herpes_LMP1 PF05297.6 KEG11582.1 - 0.56 9.0 5.8 0.62 8.9 4.0 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) CDC45 PF02724.9 KEG11582.1 - 1.1 7.2 12.9 1.2 7.0 9.0 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2201_N PF13203.1 KEG11582.1 - 1.4 8.0 9.5 1.6 7.8 6.6 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Daxx PF03344.10 KEG11582.1 - 2.6 6.4 19.6 3 6.2 13.6 1.0 1 0 0 1 1 1 0 Daxx Family eIF3_subunit PF08597.5 KEG11582.1 - 5.5 6.4 20.4 7.2 6.0 14.1 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit RRN3 PF05327.6 KEG11582.1 - 9.4 4.2 10.9 11 4.0 7.5 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Mucin PF01456.12 KEG11584.1 - 0.00096 18.9 4.3 0.00096 18.9 3.0 4.1 4 1 0 4 4 4 2 Mucin-like glycoprotein NAD_binding_4 PF07993.7 KEG11585.1 - 3.3e-05 22.9 0.0 0.0024 16.8 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 KEG11585.1 - 0.00011 22.2 0.7 0.002 18.1 0.2 2.2 2 0 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 KEG11585.1 - 0.0084 16.0 1.9 0.0099 15.8 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.16 KEG11585.1 - 0.011 15.2 0.1 0.24 10.8 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 KEG11585.1 - 0.018 14.9 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 KEG11585.1 - 0.019 14.6 0.0 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 KR domain NmrA PF05368.8 KEG11585.1 - 0.021 14.0 0.1 0.032 13.4 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family Saccharop_dh PF03435.13 KEG11585.1 - 0.21 10.5 1.8 0.38 9.6 0.2 2.1 1 1 1 2 2 2 0 Saccharopine dehydrogenase DUF4231 PF14015.1 KEG11586.1 - 0.75 9.8 10.7 0.32 11.0 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Sel1 PF08238.7 KEG11587.1 - 3.9e-19 68.6 6.1 4.5e-07 30.2 0.1 4.0 3 1 0 3 3 3 3 Sel1 repeat E1-E2_ATPase PF00122.15 KEG11588.1 - 2.4e-25 88.9 0.2 6.1e-25 87.6 0.1 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 KEG11588.1 - 9.8e-22 78.0 0.1 1.8e-21 77.2 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KEG11588.1 - 8.5e-18 65.5 0.0 4e-17 63.3 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEG11588.1 - 2e-05 24.4 0.0 4.8e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KEG11588.1 - 0.037 13.6 0.8 0.067 12.7 0.1 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Dpy-30 PF05186.8 KEG11589.1 - 2.1e-13 49.5 0.0 3.1e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif BPL_LplA_LipB PF03099.14 KEG11590.1 - 1.9e-17 63.4 0.0 3.9e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family zf-C2H2 PF00096.21 KEG11591.1 - 3.6e-08 33.2 7.6 0.00025 21.1 0.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type SSB PF00436.20 KEG11591.1 - 0.00044 20.0 0.0 0.00073 19.3 0.0 1.4 1 0 0 1 1 1 1 Single-strand binding protein family zf-C2H2_4 PF13894.1 KEG11591.1 - 0.00045 20.3 13.3 0.048 14.0 1.2 3.1 3 0 0 3 3 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KEG11591.1 - 0.00067 19.7 2.6 0.38 10.8 0.1 2.6 3 0 0 3 3 2 2 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 KEG11591.1 - 0.0025 17.9 3.4 0.43 10.7 0.3 2.5 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding DUF3505 PF12013.3 KEG11591.1 - 0.0025 18.0 0.1 0.25 11.5 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) zf-H2C2_2 PF13465.1 KEG11591.1 - 0.0058 16.8 3.3 1.6 9.1 0.1 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-met2 PF12907.2 KEG11591.1 - 0.0062 16.4 1.6 0.0062 16.4 1.1 2.5 2 0 0 2 2 2 1 Zinc-binding zf-C2H2_6 PF13912.1 KEG11591.1 - 0.011 15.5 10.3 0.067 13.1 0.1 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger DUF629 PF04780.7 KEG11591.1 - 0.022 13.3 0.6 1.8 7.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF629) C1_4 PF07975.7 KEG11591.1 - 0.023 14.7 0.5 3.7 7.6 0.0 2.6 2 0 0 2 2 2 0 TFIIH C1-like domain CpXC PF14353.1 KEG11591.1 - 0.024 14.6 0.2 9.5 6.2 0.0 2.7 3 0 0 3 3 3 0 CpXC protein zf-met PF12874.2 KEG11591.1 - 0.026 14.7 4.0 0.026 14.7 0.7 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KEG11591.1 - 0.11 12.7 3.3 0.28 11.3 0.5 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Herpes_UL3 PF03369.8 KEG11591.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL3 protein TFIIS_C PF01096.13 KEG11591.1 - 0.22 11.1 1.5 10 5.8 0.1 2.6 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) DNA_RNApol_7kD PF03604.8 KEG11591.1 - 0.42 10.1 2.7 0.77 9.2 0.1 2.5 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Med3 PF11593.3 KEG11591.1 - 9.5 5.3 14.7 13 4.9 10.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PQQ_2 PF13360.1 KEG11592.1 - 9.2e-06 25.2 4.7 0.00088 18.7 2.8 2.8 1 1 1 2 2 2 2 PQQ-like domain WD40 PF00400.27 KEG11592.1 - 0.019 14.8 4.7 0.12 12.3 0.0 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat ATG16 PF08614.6 KEG11592.1 - 0.37 10.5 29.4 0.14 11.9 4.5 3.4 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) FA_desaturase PF00487.19 KEG11593.1 - 1.8e-36 125.9 26.0 2.6e-36 125.4 18.0 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KEG11593.1 - 4.5e-05 23.1 0.0 0.0001 22.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAM110_N PF14161.1 KEG11595.1 - 0.051 13.8 4.3 0.052 13.8 3.0 1.1 1 0 0 1 1 1 0 Centrosome-associated N terminus ATP-synt_C PF00137.16 KEG11596.1 - 3e-17 62.2 12.0 3e-17 62.2 8.3 1.6 2 0 0 2 2 2 1 ATP synthase subunit C Aminotran_5 PF00266.14 KEG11598.1 - 2.2e-67 227.4 0.0 2.4e-67 227.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KEG11598.1 - 4.6e-10 39.1 0.0 5.8e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KEG11598.1 - 4.8e-05 22.5 0.1 6.2e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 KEG11598.1 - 0.00011 20.7 0.0 0.00016 20.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain AAA PF00004.24 KEG11599.1 - 6.6e-34 116.9 0.2 8.9e-28 97.1 0.1 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEG11599.1 - 4.8e-13 49.4 1.6 1.7e-05 24.8 0.0 3.3 3 1 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.1 KEG11599.1 - 1.5e-11 44.5 0.2 5.7e-05 23.2 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KEG11599.1 - 2.4e-10 39.9 1.1 0.00077 19.1 0.1 3.9 3 0 0 3 3 3 2 Part of AAA domain AAA_17 PF13207.1 KEG11599.1 - 3.3e-09 37.5 0.0 0.004 17.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KEG11599.1 - 8.3e-09 35.8 0.0 0.0016 18.7 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.9 KEG11599.1 - 3.2e-08 33.4 1.5 0.0012 18.6 0.2 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KEG11599.1 - 7.6e-08 32.3 0.0 0.0036 17.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 KEG11599.1 - 1.1e-07 31.9 0.2 0.00034 20.5 0.1 3.3 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) DUF2075 PF09848.4 KEG11599.1 - 1.2e-07 31.0 0.2 0.005 15.8 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.16 KEG11599.1 - 1.8e-07 30.5 0.1 0.006 15.7 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 KEG11599.1 - 2.8e-07 30.2 0.4 0.0085 15.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain NACHT PF05729.7 KEG11599.1 - 7.6e-07 28.9 0.5 0.014 15.0 0.0 2.9 2 1 0 2 2 2 2 NACHT domain TIP49 PF06068.8 KEG11599.1 - 1.3e-06 27.4 0.0 0.0039 15.9 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 KEG11599.1 - 6.8e-06 25.6 2.7 0.01 15.2 0.0 3.2 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 KEG11599.1 - 7.6e-06 26.0 0.1 0.086 13.0 0.0 2.7 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.22 KEG11599.1 - 1e-05 25.8 0.0 0.044 14.0 0.0 3.1 3 0 0 3 3 2 1 ABC transporter KTI12 PF08433.5 KEG11599.1 - 1.3e-05 24.5 0.1 0.0031 16.7 0.0 2.3 2 0 0 2 2 2 1 Chromatin associated protein KTI12 NB-ARC PF00931.17 KEG11599.1 - 1.8e-05 23.7 0.1 0.05 12.4 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain Zeta_toxin PF06414.7 KEG11599.1 - 1.9e-05 23.8 0.0 0.0069 15.5 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin Sigma54_activat PF00158.21 KEG11599.1 - 2.3e-05 23.9 0.0 0.26 10.7 0.0 2.6 3 0 0 3 3 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.12 KEG11599.1 - 2.4e-05 23.8 0.1 0.14 11.5 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 KEG11599.1 - 2.6e-05 24.1 0.0 0.3 10.9 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_24 PF13479.1 KEG11599.1 - 2.8e-05 23.8 0.7 0.0059 16.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KEG11599.1 - 3.5e-05 23.8 0.1 0.036 14.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KEG11599.1 - 8e-05 21.7 0.3 0.37 9.7 0.1 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus UPF0079 PF02367.12 KEG11599.1 - 9.4e-05 22.0 0.1 0.6 9.7 0.0 2.5 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 KaiC PF06745.8 KEG11599.1 - 0.0002 20.5 0.0 0.26 10.3 0.0 2.7 2 0 0 2 2 2 2 KaiC AAA_11 PF13086.1 KEG11599.1 - 0.00035 20.2 0.0 0.3 10.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KEG11599.1 - 0.0004 19.9 0.5 0.44 9.9 0.1 2.9 3 1 0 3 3 2 1 AAA-like domain ResIII PF04851.10 KEG11599.1 - 0.00059 19.7 0.0 0.11 12.2 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.12 KEG11599.1 - 0.001 18.0 0.0 1.2 7.9 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 KEG11599.1 - 0.0012 18.5 0.0 0.26 10.9 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase Zot PF05707.7 KEG11599.1 - 0.0014 18.0 0.0 0.061 12.7 0.0 2.3 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) ArgK PF03308.11 KEG11599.1 - 0.0016 17.2 0.7 0.64 8.7 0.0 2.3 2 0 0 2 2 2 1 ArgK protein Sigma54_activ_2 PF14532.1 KEG11599.1 - 0.0021 18.1 0.0 3.4 7.7 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.11 KEG11599.1 - 0.0021 17.3 0.8 0.46 9.6 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein PPV_E1_C PF00519.12 KEG11599.1 - 0.0049 15.5 0.0 0.56 8.7 0.0 2.1 2 0 0 2 2 2 1 Papillomavirus helicase cobW PF02492.14 KEG11599.1 - 0.0077 15.6 0.8 2.7 7.4 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain 6PF2K PF01591.13 KEG11599.1 - 0.013 14.6 0.0 4.6 6.2 0.0 2.3 2 0 0 2 2 2 0 6-phosphofructo-2-kinase SIMPL PF04402.9 KEG11599.1 - 0.013 15.3 0.8 0.081 12.7 0.2 2.5 4 0 0 4 4 2 0 Protein of unknown function (DUF541) DAP3 PF10236.4 KEG11599.1 - 0.018 13.9 0.4 0.35 9.7 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 NTPase_1 PF03266.10 KEG11599.1 - 0.026 14.2 0.0 5.6 6.6 0.0 2.6 2 0 0 2 2 2 0 NTPase AAA_23 PF13476.1 KEG11599.1 - 0.027 14.8 0.0 5.5 7.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Torsin PF06309.6 KEG11599.1 - 0.034 14.0 0.0 3.3 7.6 0.0 2.4 2 0 0 2 2 2 0 Torsin PIF1 PF05970.9 KEG11599.1 - 0.036 13.0 0.0 3 6.6 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase T2SE PF00437.15 KEG11599.1 - 0.039 12.8 0.2 2.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_3 PF07726.6 KEG11599.1 - 0.066 12.8 0.0 3.1 7.4 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 KEG11599.1 - 0.076 12.7 0.4 11 5.6 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 KEG11599.1 - 0.098 12.2 0.1 3.9 7.0 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KEG11599.1 - 0.099 12.1 0.1 17 4.7 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.4 KEG11599.1 - 0.1 11.2 0.1 9 4.7 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Viral_helicase1 PF01443.13 KEG11599.1 - 0.1 12.0 0.0 7.5 5.9 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ATP_bind_1 PF03029.12 KEG11599.1 - 0.15 11.5 0.0 6.7 6.1 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SecA_DEAD PF07517.9 KEG11599.1 - 0.32 10.2 1.8 1.4 8.1 0.1 2.4 2 1 0 3 3 2 0 SecA DEAD-like domain EBP PF05241.7 KEG11600.1 - 5.7e-29 100.5 0.5 7.1e-29 100.2 0.4 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF2157 PF09925.4 KEG11600.1 - 0.0046 16.5 2.3 0.11 12.1 0.7 2.2 2 0 0 2 2 2 2 Predicted membrane protein (DUF2157) DUF2781 PF10914.3 KEG11600.1 - 1 9.1 7.1 3.4 7.4 4.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2781) TFIIF_alpha PF05793.7 KEG11601.1 - 1.1 7.4 63.0 1.7 6.9 43.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TraT PF05818.7 KEG11601.1 - 4.5 6.6 7.4 7.9 5.8 5.1 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein MRP PF09387.5 KEG11602.1 - 3.2e-57 193.3 0.0 4.1e-57 193.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial RNA binding protein MRP WGG PF10273.4 KEG11603.1 - 0.0001 22.2 3.2 0.00067 19.6 2.2 2.0 1 1 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Alliinase_C PF04864.8 KEG11603.1 - 0.03 12.9 0.1 0.041 12.5 0.0 1.1 1 0 0 1 1 1 0 Allinase TPR_11 PF13414.1 KEG11605.1 - 9.7e-33 111.6 29.6 1.2e-11 44.0 2.5 7.0 5 1 0 6 6 6 5 TPR repeat TPR_12 PF13424.1 KEG11605.1 - 8.1e-32 108.9 31.4 5.3e-09 35.9 1.3 8.5 4 3 4 8 8 8 8 Tetratricopeptide repeat TPR_16 PF13432.1 KEG11605.1 - 8.2e-25 86.8 13.7 4.3e-06 27.2 0.0 7.0 5 1 3 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.23 KEG11605.1 - 1.2e-21 75.3 39.4 0.00025 20.5 1.0 10.7 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_2 PF07719.12 KEG11605.1 - 3.2e-20 70.3 39.3 0.002 17.9 0.6 11.8 12 0 0 12 12 12 6 Tetratricopeptide repeat TPR_19 PF14559.1 KEG11605.1 - 2.9e-19 69.1 13.3 3.8e-05 23.9 0.0 7.6 5 3 4 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 KEG11605.1 - 9.9e-18 63.0 8.7 0.0063 17.0 0.0 10.3 4 3 7 11 11 11 2 Tetratricopeptide repeat TPR_6 PF13174.1 KEG11605.1 - 6.8e-15 54.4 25.7 0.003 17.8 0.0 10.9 13 0 0 13 13 11 3 Tetratricopeptide repeat TPR_7 PF13176.1 KEG11605.1 - 1.1e-14 52.9 18.6 0.034 13.9 0.0 9.5 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_8 PF13181.1 KEG11605.1 - 1.2e-12 46.6 38.1 0.0067 16.1 0.7 10.7 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_10 PF13374.1 KEG11605.1 - 3.3e-12 45.9 11.5 0.48 10.4 0.0 8.0 7 0 0 7 7 7 3 Tetratricopeptide repeat Apc3 PF12895.2 KEG11605.1 - 1.6e-11 44.1 30.8 8.3e-06 25.8 0.2 6.4 5 1 2 7 7 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 KEG11605.1 - 3.3e-11 42.4 20.9 0.042 14.0 0.8 9.3 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 KEG11605.1 - 5.7e-05 22.8 3.5 2 8.2 0.0 4.7 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_21 PF09976.4 KEG11605.1 - 0.00048 20.0 10.8 0.0013 18.7 0.2 3.2 3 1 0 3 3 2 1 Tetratricopeptide repeat TPR_4 PF07721.9 KEG11605.1 - 0.0013 18.9 0.7 16 6.2 0.1 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.15 KEG11605.1 - 0.0017 18.2 12.5 3.1 7.9 0.0 7.0 8 0 0 8 8 7 2 PPR repeat Fis1_TPR_C PF14853.1 KEG11605.1 - 0.15 11.9 20.4 1.5 8.7 0.3 6.6 6 1 1 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat CW_binding_1 PF01473.15 KEG11606.1 - 0.17 12.0 1.3 0.37 11.0 0.9 1.6 1 0 0 1 1 1 0 Putative cell wall binding repeat MFS_1 PF07690.11 KEG11607.1 - 2.4e-35 121.8 43.3 1.6e-19 69.8 13.5 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEG11607.1 - 1.9e-05 23.4 13.9 1.9e-05 23.4 9.6 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter ATG22 PF11700.3 KEG11607.1 - 0.42 9.0 26.2 1.5 7.2 7.3 3.1 2 1 1 3 3 3 0 Vacuole effluxer Atg22 like JmjC PF02373.17 KEG11608.1 - 4.5e-13 49.4 0.3 2.1e-11 44.0 0.2 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 KEG11608.1 - 0.0018 17.8 0.0 0.017 14.6 0.0 2.2 1 1 0 1 1 1 1 Cupin-like domain 2OG-FeII_Oxy_5 PF13759.1 KEG11608.1 - 0.042 14.1 0.0 1 9.6 0.0 2.5 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase RAI16-like PF10257.4 KEG11609.1 - 2.5e-10 39.8 0.0 1.1e-09 37.7 0.0 1.9 1 1 0 1 1 1 1 Retinoic acid induced 16-like protein TetR_C_7 PF14246.1 KEG11609.1 - 0.066 13.4 1.4 0.21 11.8 0.1 2.5 2 0 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal region eIF-1a PF01176.14 KEG11610.1 - 0.013 14.8 0.4 0.029 13.7 0.2 1.5 2 0 0 2 2 2 0 Translation initiation factor 1A / IF-1 Ipi1_N PF12333.3 KEG11611.1 - 4.2e-05 23.4 4.8 0.0061 16.5 0.2 3.9 5 1 1 6 6 6 2 Rix1 complex component involved in 60S ribosome maturation HEAT PF02985.17 KEG11611.1 - 1.2 9.3 4.2 0.86 9.8 0.2 3.0 3 0 0 3 3 3 0 HEAT repeat Cmc1 PF08583.5 KEG11612.1 - 0.0021 17.8 4.9 0.0021 17.8 3.4 1.8 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like Med15_fungi PF05397.7 KEG11612.1 - 0.023 14.6 0.1 0.041 13.8 0.1 1.4 1 0 0 1 1 1 0 Mediator complex subunit 15 TfoX_N PF04993.8 KEG11612.1 - 0.064 13.1 1.2 0.095 12.5 0.1 1.8 2 0 0 2 2 2 0 TfoX N-terminal domain Papo_T_antigen PF02380.10 KEG11612.1 - 0.3 11.0 3.7 0.13 12.1 0.9 1.7 2 0 0 2 2 2 0 T-antigen specific domain Snurportin1 PF11538.3 KEG11612.1 - 0.6 9.9 4.7 18 5.1 0.1 3.4 3 0 0 3 3 3 0 Snurportin1 UPF0203 PF05254.7 KEG11612.1 - 0.64 9.9 5.9 0.24 11.2 1.8 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) tRNA_SAD PF07973.9 KEG11613.1 - 4.5e-06 26.4 0.3 1.1e-05 25.1 0.2 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.14 KEG11613.1 - 0.0032 15.8 0.0 0.0041 15.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) F-box PF00646.28 KEG11614.1 - 0.00081 18.9 1.0 0.002 17.7 0.7 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KEG11614.1 - 0.0013 18.3 1.9 0.0035 17.0 1.3 1.7 1 0 0 1 1 1 1 F-box-like FAD_binding_3 PF01494.14 KEG11616.1 - 2.3e-08 33.4 1.8 0.1 11.6 0.1 3.1 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.19 KEG11616.1 - 7e-05 21.8 2.2 0.00016 20.7 0.6 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KEG11616.1 - 0.00063 20.0 0.1 0.0016 18.8 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KEG11616.1 - 0.01 15.4 0.1 0.025 14.1 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 KEG11616.1 - 0.029 14.3 0.0 0.058 13.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_8 PF13450.1 KEG11616.1 - 0.032 14.2 0.0 0.12 12.3 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 KEG11616.1 - 0.034 13.7 0.1 0.064 12.9 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_16 PF10294.4 KEG11617.1 - 1.7e-08 34.1 0.0 8.6e-05 22.0 0.0 2.2 1 1 1 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 KEG11617.1 - 0.0002 21.9 0.0 0.00035 21.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KEG11617.1 - 0.00048 19.3 0.0 0.00072 18.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 KEG11617.1 - 0.0056 17.0 0.1 0.011 16.0 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF2186 PF09952.4 KEG11617.1 - 0.06 13.6 0.1 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2186) Amastin PF07344.6 KEG11618.1 - 9.1e-32 109.8 27.0 2.6e-20 72.5 8.4 2.1 2 0 0 2 2 2 2 Amastin surface glycoprotein PMP22_Claudin PF00822.15 KEG11618.1 - 1.1e-08 34.9 22.3 4.3e-07 29.7 1.5 2.2 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family DUF1366 PF07104.6 KEG11620.1 - 0.043 13.4 2.8 0.12 12.0 2.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) Kinesin PF00225.18 KEG11623.1 - 2.6e-05 23.0 0.0 3.7e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain DOT1 PF08123.8 KEG11625.1 - 3.7e-16 59.0 0.1 5.8e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 KEG11625.1 - 9.1e-05 22.4 0.0 0.00016 21.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEG11625.1 - 0.00028 21.4 0.0 0.00048 20.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEG11625.1 - 0.00034 20.2 0.0 0.0009 18.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 KEG11625.1 - 0.00042 19.4 0.1 0.001 18.1 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase DUF3594 PF12165.3 KEG11625.1 - 0.03 13.9 0.1 0.059 13.0 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3594) HMG_CoA_synt_N PF01154.12 KEG11625.1 - 0.096 12.2 0.1 1.7 8.1 0.0 2.1 1 1 1 2 2 2 0 Hydroxymethylglutaryl-coenzyme A synthase N terminal Antimicrobial17 PF08129.6 KEG11625.1 - 0.13 12.1 0.3 10 5.9 0.0 2.8 2 1 1 3 3 3 0 Alpha/beta enterocin family V-ATPase_H_N PF03224.9 KEG11626.1 - 0.00038 19.6 3.0 0.0037 16.4 0.0 3.1 3 1 0 3 3 3 1 V-ATPase subunit H LisH PF08513.6 KEG11626.1 - 0.0068 16.1 0.0 0.0068 16.1 0.0 2.0 2 0 0 2 2 2 1 LisH WD40 PF00400.27 KEG11626.1 - 0.14 12.0 0.9 19 5.2 0.0 3.7 3 0 0 3 3 3 0 WD domain, G-beta repeat DUF2721 PF11026.3 KEG11627.1 - 0.043 13.4 8.3 1.1 8.9 2.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) DUF4231 PF14015.1 KEG11627.1 - 0.052 13.5 1.3 0.072 13.0 0.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) H_PPase PF03030.11 KEG11627.1 - 0.075 11.2 0.2 0.085 11.0 0.2 1.1 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase DUF3357 PF11837.3 KEG11627.1 - 0.39 10.5 2.3 2.6 7.9 0.6 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) DUF4234 PF14018.1 KEG11627.1 - 0.68 9.7 2.9 3.4 7.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) Syndecan PF01034.15 KEG11627.1 - 2.9 7.5 6.7 0.58 9.8 0.1 2.8 1 1 2 3 3 3 0 Syndecan domain DUF4131 PF13567.1 KEG11627.1 - 5.6 6.3 15.4 0.25 10.7 3.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DER1 PF04511.10 KEG11628.1 - 4.1e-31 108.0 12.3 4.9e-31 107.7 8.5 1.0 1 0 0 1 1 1 1 Der1-like family SAM_2 PF07647.12 KEG11629.1 - 4.1e-11 42.5 0.0 7.1e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KEG11629.1 - 1.1e-05 25.5 0.0 2.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.1 KEG11629.1 - 0.17 12.1 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain Pkinase PF00069.20 KEG11632.1 - 2.2e-51 174.5 0.0 2.6e-51 174.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG11632.1 - 6e-21 74.6 0.0 8.1e-21 74.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEG11632.1 - 0.00044 20.0 0.0 0.009 15.7 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family ABC1 PF03109.11 KEG11632.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 ABC1 family Kdo PF06293.9 KEG11632.1 - 0.043 12.8 0.0 0.069 12.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC_membrane_2 PF06472.10 KEG11633.1 - 1.2e-77 260.8 2.1 1.8e-77 260.2 1.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KEG11633.1 - 2.3e-13 50.5 0.0 5.1e-13 49.4 0.0 1.6 1 1 0 1 1 1 1 ABC transporter NACHT PF05729.7 KEG11633.1 - 0.04 13.5 0.0 0.093 12.3 0.0 1.7 1 0 0 1 1 1 0 NACHT domain SMC_N PF02463.14 KEG11633.1 - 0.051 12.7 0.0 1.3 8.2 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KEG11633.1 - 0.21 11.5 0.0 0.41 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NOG1 PF06858.9 KEG11634.1 - 1.5e-27 95.2 0.0 3.3e-27 94.1 0.0 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.6 KEG11634.1 - 2.4e-24 84.7 5.6 5.9e-24 83.5 3.9 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.18 KEG11634.1 - 1.1e-16 60.7 0.0 2.5e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KEG11634.1 - 1.7e-09 37.1 0.0 3.7e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 KEG11634.1 - 0.00013 22.4 0.0 0.00033 21.1 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 KEG11634.1 - 0.017 14.3 0.0 0.031 13.5 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AIG1 PF04548.11 KEG11634.1 - 0.021 13.9 0.0 0.043 12.9 0.0 1.5 1 0 0 1 1 1 0 AIG1 family ArgK PF03308.11 KEG11634.1 - 0.059 12.1 0.0 0.23 10.1 0.0 1.9 2 0 0 2 2 2 0 ArgK protein Dynamin_N PF00350.18 KEG11634.1 - 0.061 13.1 0.3 19 5.0 0.0 3.3 2 1 1 3 3 3 0 Dynamin family Pcc1 PF09341.5 KEG11636.1 - 8.7e-19 67.3 0.4 1e-18 67.0 0.2 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 EF1_GNE PF00736.14 KEG11637.1 - 1.4e-29 101.5 0.8 3.2e-29 100.4 0.6 1.6 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain Ribosomal_60s PF00428.14 KEG11637.1 - 0.0015 18.8 7.4 0.0015 18.8 5.1 2.7 1 1 1 2 2 2 1 60s Acidic ribosomal protein zf-RanBP PF00641.13 KEG11638.1 - 1.4e-13 49.6 97.2 1.7e-05 23.8 0.8 10.1 10 0 0 10 10 10 9 Zn-finger in Ran binding protein and others DZR PF12773.2 KEG11638.1 - 2.5e-12 46.4 79.5 0.0032 17.2 7.6 7.1 4 2 3 7 7 7 7 Double zinc ribbon DZR PF12773.2 KEG11639.1 - 5.6e-08 32.4 168.1 0.036 13.8 9.3 12.5 6 2 8 14 14 14 10 Double zinc ribbon zf-RanBP PF00641.13 KEG11639.1 - 6.6e-06 25.1 18.9 0.00021 20.3 3.5 18.1 17 1 2 19 19 19 10 Zn-finger in Ran binding protein and others DUF4109 PF13397.1 KEG11639.1 - 9.2 6.7 31.1 1.3 9.4 1.0 7.0 6 2 1 7 7 7 0 Domain of unknown function (DUF4109) ARL2_Bind_BART PF11527.3 KEG11640.1 - 4.3e-35 120.1 0.3 9.7e-35 118.9 0.2 1.6 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART Tom5 PF10642.4 KEG11640.1 - 0.27 10.8 3.3 0.37 10.4 0.5 2.5 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase UIM PF02809.15 KEG11640.1 - 1.6 8.5 13.0 1.1 9.0 0.8 3.2 3 0 0 3 3 3 0 Ubiquitin interaction motif TATR PF03430.8 KEG11640.1 - 4 5.9 11.9 0.08 11.5 3.5 1.6 2 0 0 2 2 2 0 Trans-activating transcriptional regulator ECM1 PF05782.6 KEG11640.1 - 9.3 4.8 9.3 14 4.2 6.4 1.2 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) MscS_porin PF12795.2 KEG11642.1 - 0.0029 16.9 19.2 0.0051 16.1 13.3 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain MAD PF05557.8 KEG11642.1 - 0.0094 14.0 13.0 0.014 13.5 9.0 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein DUF2968 PF11180.3 KEG11642.1 - 0.014 14.7 16.3 0.023 14.0 11.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) IncA PF04156.9 KEG11642.1 - 0.13 11.8 13.2 0.23 11.0 9.2 1.3 1 0 0 1 1 1 0 IncA protein Strep_SA_rep PF06696.6 KEG11642.1 - 0.18 11.5 3.5 0.42 10.4 2.4 1.6 1 0 0 1 1 1 0 Streptococcal surface antigen repeat TPR_MLP1_2 PF07926.7 KEG11642.1 - 0.31 10.8 13.7 0.67 9.7 9.5 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF3584 PF12128.3 KEG11642.1 - 0.53 7.5 13.8 0.74 7.0 9.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Erp_C PF06780.6 KEG11642.1 - 0.59 9.9 4.5 12 5.6 0.1 2.4 1 1 1 2 2 2 0 Erp protein C-terminus DUF4407 PF14362.1 KEG11642.1 - 0.84 8.5 10.3 1.4 7.7 7.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_13 PF13166.1 KEG11642.1 - 1.8 6.9 7.7 0.13 10.6 0.2 1.9 1 1 1 2 2 2 0 AAA domain ATG16 PF08614.6 KEG11642.1 - 1.9 8.2 14.6 4.6 7.0 5.7 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF3847 PF12958.2 KEG11642.1 - 3.4 7.4 13.0 1.7 8.4 2.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) TBPIP PF07106.8 KEG11642.1 - 3.8 7.0 12.1 2.7 7.4 0.7 2.4 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HR1 PF02185.11 KEG11642.1 - 4.3 7.1 12.2 13 5.6 2.8 2.8 2 0 0 2 2 2 0 Hr1 repeat Mnd1 PF03962.10 KEG11642.1 - 9.1 5.8 11.0 19 4.8 7.6 1.4 1 0 0 1 1 1 0 Mnd1 family Trypsin_2 PF13365.1 KEG11643.1 - 6.6e-06 26.1 0.0 1.2e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Atx10homo_assoc PF09759.4 KEG11643.1 - 0.078 12.7 0.0 0.61 9.8 0.0 2.2 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain Aa_trans PF01490.13 KEG11644.1 - 6.1e-47 160.0 23.0 8.9e-47 159.4 15.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AAA PF00004.24 KEG11645.1 - 4.1e-96 318.2 0.0 3.2e-47 160.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 KEG11645.1 - 1.8e-20 72.6 0.1 5.7e-20 71.0 0.1 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_17 PF13207.1 KEG11645.1 - 1.4e-13 51.7 0.1 4.6e-05 24.2 0.0 3.8 3 1 0 3 3 3 2 AAA domain RuvB_N PF05496.7 KEG11645.1 - 1.7e-13 50.1 0.0 7.2e-06 25.2 0.0 2.6 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KEG11645.1 - 7.3e-13 48.9 0.6 4.3e-05 23.5 0.0 3.8 3 2 1 4 4 3 2 AAA ATPase domain AAA_33 PF13671.1 KEG11645.1 - 4.9e-12 45.9 0.0 5.3e-06 26.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KEG11645.1 - 2.5e-11 43.8 0.2 0.00065 19.8 0.0 4.1 2 2 0 2 2 2 2 AAA domain AAA_2 PF07724.9 KEG11645.1 - 3.9e-11 43.1 0.0 5.1e-06 26.4 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KEG11645.1 - 7.5e-11 41.9 0.5 6.2e-05 22.7 0.0 4.0 4 2 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KEG11645.1 - 2.6e-09 37.0 0.0 0.00082 19.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KEG11645.1 - 4.3e-09 35.7 0.0 0.0018 17.4 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin TIP49 PF06068.8 KEG11645.1 - 1.9e-08 33.4 0.0 0.00049 18.9 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus CDC48_2 PF02933.12 KEG11645.1 - 2.8e-08 33.2 0.0 5.9e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_18 PF13238.1 KEG11645.1 - 6.8e-08 32.8 0.0 0.0042 17.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KEG11645.1 - 9.3e-08 31.6 4.4 0.05 12.9 0.0 4.3 2 2 2 4 4 4 1 AAA domain IstB_IS21 PF01695.12 KEG11645.1 - 1.2e-07 31.3 0.1 0.012 15.0 0.0 2.8 3 0 0 3 3 2 2 IstB-like ATP binding protein RNA_helicase PF00910.17 KEG11645.1 - 3.1e-07 30.5 0.0 0.0056 16.8 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.16 KEG11645.1 - 4.4e-07 29.2 0.2 0.027 13.6 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KEG11645.1 - 1.9e-06 27.5 1.4 0.035 13.8 0.2 2.6 2 0 0 2 2 2 2 Part of AAA domain AAA_28 PF13521.1 KEG11645.1 - 2.5e-06 27.5 0.0 0.16 11.9 0.0 3.2 3 0 0 3 3 3 2 AAA domain Arch_ATPase PF01637.13 KEG11645.1 - 4.5e-06 26.5 0.1 1.2 8.7 0.0 3.3 2 1 1 3 3 3 2 Archaeal ATPase ABC_tran PF00005.22 KEG11645.1 - 1.2e-05 25.6 0.0 0.038 14.2 0.0 3.2 2 1 0 2 2 2 1 ABC transporter NACHT PF05729.7 KEG11645.1 - 1.3e-05 24.9 0.1 0.15 11.6 0.0 3.5 3 1 1 4 4 4 2 NACHT domain Vps4_C PF09336.5 KEG11645.1 - 1.4e-05 24.8 0.0 0.00052 19.8 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain ResIII PF04851.10 KEG11645.1 - 1.7e-05 24.7 0.0 0.0046 16.8 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Sigma54_activat PF00158.21 KEG11645.1 - 3e-05 23.5 0.0 0.068 12.6 0.0 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 KEG11645.1 - 3.1e-05 24.0 0.0 0.073 13.1 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Parvo_NS1 PF01057.12 KEG11645.1 - 3.3e-05 22.9 0.0 0.047 12.5 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_24 PF13479.1 KEG11645.1 - 5.9e-05 22.7 0.0 0.33 10.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 KEG11645.1 - 0.00011 21.7 0.0 0.011 15.2 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Bac_DnaA PF00308.13 KEG11645.1 - 0.00012 21.8 0.0 0.17 11.4 0.0 2.5 2 0 0 2 2 2 2 Bacterial dnaA protein KaiC PF06745.8 KEG11645.1 - 0.00017 20.8 2.0 1.3 8.0 0.0 3.8 3 1 1 4 4 4 1 KaiC NB-ARC PF00931.17 KEG11645.1 - 0.00027 19.8 0.0 0.6 8.9 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain NTPase_1 PF03266.10 KEG11645.1 - 0.00034 20.3 1.6 2.6 7.7 0.0 4.3 3 1 1 4 4 4 1 NTPase AAA_3 PF07726.6 KEG11645.1 - 0.00058 19.4 0.0 1.3 8.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 KEG11645.1 - 0.00091 18.5 0.2 0.75 8.9 0.0 2.7 2 0 0 2 2 2 1 PhoH-like protein DUF2075 PF09848.4 KEG11645.1 - 0.0037 16.2 0.0 0.99 8.3 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Cytidylate_kin2 PF13189.1 KEG11645.1 - 0.0043 16.9 0.0 0.41 10.5 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family SKI PF01202.17 KEG11645.1 - 0.0051 16.6 0.0 3.3 7.5 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase AAA_23 PF13476.1 KEG11645.1 - 0.0058 16.9 0.0 4.7 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KEG11645.1 - 0.0089 15.4 0.2 4.2 6.7 0.0 3.5 3 1 1 4 4 4 0 AAA-like domain T2SE PF00437.15 KEG11645.1 - 0.012 14.5 0.0 8.4 5.2 0.0 3.1 3 0 0 3 3 3 0 Type II/IV secretion system protein UPF0079 PF02367.12 KEG11645.1 - 0.013 15.0 0.0 6.4 6.4 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Molydop_binding PF01568.16 KEG11645.1 - 0.015 15.1 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain UFD1 PF03152.9 KEG11645.1 - 0.017 14.2 0.0 0.036 13.2 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 AAA_21 PF13304.1 KEG11645.1 - 0.017 15.0 0.5 10 6.0 0.3 3.4 2 1 0 2 2 2 0 AAA domain DEAD PF00270.24 KEG11645.1 - 0.019 14.4 0.1 9.6 5.6 0.0 3.4 3 1 0 4 4 3 0 DEAD/DEAH box helicase DUF815 PF05673.8 KEG11645.1 - 0.025 13.4 0.0 4.4 6.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) KTI12 PF08433.5 KEG11645.1 - 0.048 12.8 0.1 8.1 5.5 0.0 2.5 2 1 0 2 2 2 0 Chromatin associated protein KTI12 AAA_29 PF13555.1 KEG11645.1 - 0.055 13.0 0.0 9 5.9 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_11 PF13086.1 KEG11645.1 - 0.093 12.2 0.0 7.8 5.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zot PF05707.7 KEG11645.1 - 0.1 12.0 0.2 8.8 5.7 0.1 3.2 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) AFG1_ATPase PF03969.11 KEG11645.1 - 0.15 10.8 0.0 8.7 5.0 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase cNMP_binding PF00027.24 KEG11647.1 - 1.4e-21 76.1 0.0 5.6e-15 54.9 0.0 3.4 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain C2 PF00168.25 KEG11647.1 - 1.5e-11 43.9 0.0 0.0086 15.8 0.0 4.5 4 0 0 4 4 4 4 C2 domain Arf PF00025.16 KEG11648.1 - 1e-28 99.7 0.0 1.6e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KEG11648.1 - 3.1e-10 39.3 0.0 6.6e-10 38.2 0.0 1.5 1 1 0 1 1 1 1 G-protein alpha subunit MMR_HSR1 PF01926.18 KEG11648.1 - 2e-07 30.9 0.0 3.5e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KEG11648.1 - 2e-07 30.4 0.0 2.8e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 KEG11648.1 - 3.3e-07 29.8 0.0 5.1e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.22 KEG11648.1 - 0.00014 21.3 0.5 0.0093 15.4 0.3 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 KEG11648.1 - 0.00018 21.9 0.0 0.00039 20.8 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 KEG11648.1 - 0.018 14.1 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 KEG11648.1 - 0.098 11.9 0.1 0.23 10.7 0.1 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B Tfb2 PF03849.9 KEG11650.1 - 9.6e-24 83.6 0.0 1.3e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 KEG11650.1 - 7.7e-05 22.4 0.0 0.00022 20.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Cation_efflux PF01545.16 KEG11652.1 - 3.4e-39 134.6 1.7 4.1e-39 134.3 1.2 1.0 1 0 0 1 1 1 1 Cation efflux family DUF2946 PF11162.3 KEG11652.1 - 0.51 10.5 8.1 1.6 8.9 5.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2946) TPR_2 PF07719.12 KEG11654.1 - 0.00012 21.6 0.1 0.0003 20.4 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEG11654.1 - 0.0061 16.1 0.5 0.014 15.0 0.4 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 KEG11654.1 - 0.017 14.7 0.1 0.034 13.7 0.1 1.4 1 0 0 1 1 1 0 TPR repeat Vps39_1 PF10366.4 KEG11655.1 - 0.08 12.9 0.1 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 Pkinase PF00069.20 KEG11656.1 - 5.4e-53 179.7 0.0 8.3e-53 179.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG11656.1 - 1.6e-36 125.6 0.0 3.6e-36 124.5 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_2 PF07719.12 KEG11656.1 - 0.00022 20.9 0.1 0.00062 19.4 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat Kinase-like PF14531.1 KEG11656.1 - 0.00058 18.9 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KEG11656.1 - 0.0046 16.3 0.0 0.0088 15.4 0.0 1.4 1 0 0 1 1 1 1 RIO1 family TPR_1 PF00515.23 KEG11656.1 - 0.0088 15.6 0.4 0.022 14.3 0.3 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat MGS PF02142.17 KEG11656.1 - 0.013 15.4 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 MGS-like domain TPR_11 PF13414.1 KEG11656.1 - 0.08 12.6 0.1 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 TPR repeat HAMP PF00672.20 KEG11656.1 - 0.3 11.3 0.0 0.3 11.3 0.0 2.2 2 0 0 2 2 2 0 HAMP domain Fascin PF06268.8 KEG11658.1 - 2.7e-07 30.6 0.2 9.9e-07 28.8 0.0 2.0 2 1 0 2 2 2 1 Fascin domain RIC1 PF07064.8 KEG11659.1 - 1.8e-57 194.7 0.0 3.2e-57 193.9 0.0 1.3 1 0 0 1 1 1 1 RIC1 Cyclin_N PF00134.18 KEG11660.1 - 4.7e-08 32.6 1.0 9.1e-08 31.7 0.7 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain RRM_6 PF14259.1 KEG11661.1 - 2.9e-14 52.7 0.1 3.8e-07 30.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEG11661.1 - 1.5e-13 50.1 1.3 4.6e-06 26.1 0.3 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG11661.1 - 6.7e-08 32.2 0.4 0.00058 19.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Herpes_IE2_3 PF03361.9 KEG11661.1 - 0.049 12.9 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Herpes virus intermediate/early protein 2/3 HpaP PF09483.5 KEG11661.1 - 1.7 8.5 8.1 3.2 7.6 5.6 1.5 1 0 0 1 1 1 0 Type III secretion protein (HpaP) Epimerase PF01370.16 KEG11662.1 - 4.8e-56 189.8 0.0 6.2e-56 189.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KEG11662.1 - 1.7e-09 37.0 0.0 9.7e-07 27.9 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain 3Beta_HSD PF01073.14 KEG11662.1 - 2.2e-07 29.9 0.6 3.3e-06 26.0 0.4 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KEG11662.1 - 2.1e-06 26.8 3.2 1.7e-05 23.8 0.1 2.9 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 KEG11662.1 - 0.00015 20.8 0.0 0.0012 17.7 0.0 2.0 1 1 1 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 KEG11662.1 - 0.01 15.8 0.1 0.12 12.4 0.0 2.5 2 1 0 2 2 2 0 NADH(P)-binding LRR_4 PF12799.2 KEG11663.1 - 1.5e-21 75.5 1.8 1.2e-07 31.2 1.6 3.9 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG11663.1 - 1.3e-17 63.2 28.8 7.4e-07 28.8 2.3 3.7 1 1 5 6 6 6 6 Leucine rich repeat LRR_6 PF13516.1 KEG11663.1 - 1.5e-08 33.7 8.4 0.13 12.4 0.2 5.7 5 1 1 6 6 6 3 Leucine Rich repeat LRR_9 PF14580.1 KEG11663.1 - 8.8e-06 25.3 0.0 0.0035 16.9 0.0 2.6 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.28 KEG11663.1 - 1.7e-05 24.2 7.1 0.063 13.3 0.3 5.3 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_7 PF13504.1 KEG11663.1 - 0.014 15.4 11.5 0.059 13.5 1.1 4.4 5 0 0 5 5 5 0 Leucine rich repeat Acetyltransf_11 PF13720.1 KEG11663.1 - 3.5 7.8 5.5 14 6.0 0.3 2.5 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Pkinase PF00069.20 KEG11664.1 - 0.0029 16.8 0.0 0.032 13.3 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain DUF4131 PF13567.1 KEG11665.1 - 3 7.2 6.0 3.4 7.0 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) NUDIX PF00293.23 KEG11666.1 - 4.2e-13 49.1 0.0 7e-13 48.3 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain EF-hand_7 PF13499.1 KEG11668.1 - 5.4e-30 103.3 0.3 6.4e-16 58.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KEG11668.1 - 7.7e-29 96.7 6.0 8.5e-08 30.9 0.3 4.1 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 KEG11668.1 - 2.6e-23 81.3 3.8 2.2e-11 43.1 0.0 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 KEG11668.1 - 7.4e-21 72.1 1.7 6.3e-06 25.6 0.1 4.3 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KEG11668.1 - 6.6e-17 60.0 6.0 3.8e-06 25.9 0.3 4.0 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.2 KEG11668.1 - 3.4e-07 29.9 0.2 0.023 14.4 0.0 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KEG11668.1 - 1.1e-06 28.4 0.1 0.011 15.5 0.0 2.6 2 2 1 3 3 3 2 EF-hand domain UPF0154 PF03672.8 KEG11668.1 - 0.04 13.5 0.0 7.5 6.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) SPARC_Ca_bdg PF10591.4 KEG11668.1 - 0.081 12.9 0.0 8.5 6.4 0.0 2.2 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Pkinase PF00069.20 KEG11669.1 - 1.3e-55 188.3 0.0 2.9e-55 187.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG11669.1 - 1.4e-34 119.3 0.0 5.4e-34 117.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase PAS PF00989.19 KEG11669.1 - 8e-05 22.3 0.0 0.00034 20.3 0.0 2.1 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 KEG11669.1 - 0.00027 21.2 0.0 0.0016 18.7 0.0 2.3 2 0 0 2 2 2 1 PAS domain Kinase-like PF14531.1 KEG11669.1 - 0.0093 14.9 0.0 0.019 13.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEG11669.1 - 0.023 14.4 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 KEG11669.1 - 0.051 12.9 0.0 0.26 10.5 0.0 2.0 2 0 0 2 2 2 0 RIO1 family PAS_4 PF08448.5 KEG11669.1 - 0.066 13.2 0.1 0.3 11.1 0.0 2.1 2 0 0 2 2 2 0 PAS fold FtsK_SpoIIIE PF01580.13 KEG11672.1 - 0.013 14.9 0.1 0.018 14.4 0.1 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_19 PF13245.1 KEG11672.1 - 0.045 13.5 0.3 0.085 12.6 0.2 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 KEG11672.1 - 0.068 13.3 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KEG11672.1 - 0.097 12.6 0.1 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.21 KEG11672.1 - 0.11 11.9 0.1 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain G-alpha PF00503.15 KEG11672.1 - 0.15 10.7 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit DUF498 PF04430.9 KEG11674.1 - 1.2e-22 79.5 0.0 2.1e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) tRNA_int_endo PF01974.12 KEG11675.1 - 2e-13 49.9 0.0 3.4e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Ribosomal_L34e PF01199.13 KEG11676.1 - 5.4e-14 52.1 2.7 6.9e-14 51.8 1.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e ChlamPMP_M PF07548.6 KEG11677.1 - 5.8e-05 22.8 2.2 0.0001 22.0 1.5 1.4 1 0 0 1 1 1 1 Chlamydia polymorphic membrane protein middle domain DUF4164 PF13747.1 KEG11677.1 - 0.017 15.2 9.3 0.072 13.2 0.2 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) ECM11 PF15463.1 KEG11677.1 - 0.049 13.9 0.5 0.049 13.9 0.3 2.8 2 1 1 3 3 3 0 Extracellular mutant protein 11 Mod_r PF07200.8 KEG11677.1 - 0.1 12.5 17.4 0.46 10.4 1.7 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Reo_sigmaC PF04582.7 KEG11677.1 - 0.47 9.5 8.3 0.21 10.7 0.3 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Syntaxin PF00804.20 KEG11677.1 - 0.51 10.5 7.9 20 5.3 5.5 2.3 1 1 0 1 1 1 0 Syntaxin H-kinase_dim PF02895.9 KEG11677.1 - 0.78 10.1 9.7 1.3 9.3 1.5 3.3 2 1 1 3 3 3 0 Signal transducing histidine kinase, homodimeric domain AAA_13 PF13166.1 KEG11677.1 - 1.1 7.6 13.1 0.029 12.8 2.0 2.0 1 1 1 2 2 2 0 AAA domain COG2 PF06148.6 KEG11677.1 - 1.2 9.0 11.8 7.2 6.4 1.6 3.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 IncA PF04156.9 KEG11677.1 - 1.3 8.5 16.0 0.47 10.0 0.4 2.2 1 1 1 2 2 2 0 IncA protein Fzo_mitofusin PF04799.8 KEG11677.1 - 1.5 8.2 12.4 0.082 12.2 0.7 2.8 1 1 2 3 3 3 0 fzo-like conserved region Tweety PF04906.8 KEG11677.1 - 1.5 7.1 11.5 0.021 13.2 0.7 2.0 1 1 1 2 2 2 0 Tweety Laminin_II PF06009.7 KEG11677.1 - 1.8 8.3 12.6 0.09 12.5 1.1 2.7 1 1 2 3 3 3 0 Laminin Domain II KLRAQ PF10205.4 KEG11677.1 - 2 8.4 11.2 0.74 9.8 2.2 2.9 1 1 3 4 4 4 0 Predicted coiled-coil domain-containing protein DUF342 PF03961.8 KEG11677.1 - 3.2 6.0 14.6 2.1 6.6 6.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF2968 PF11180.3 KEG11677.1 - 3.2 7.0 17.3 0.41 9.9 2.2 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF2968) DUF948 PF06103.6 KEG11677.1 - 3.7 7.4 14.1 0.73 9.7 0.8 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Striatin PF08232.7 KEG11677.1 - 4.9 7.4 15.4 4.8 7.4 0.7 2.1 1 1 1 2 2 2 0 Striatin family MerR-DNA-bind PF09278.6 KEG11677.1 - 5 7.5 9.5 43 4.5 0.7 3.7 2 1 0 3 3 3 0 MerR, DNA binding ADIP PF11559.3 KEG11677.1 - 8.8 6.2 19.9 7.5 6.4 0.3 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.5 KEG11677.1 - 9.9 6.2 14.0 0.8 9.8 1.2 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family PI3_PI4_kinase PF00454.22 KEG11678.1 - 5.1e-37 127.5 0.0 1.4e-35 122.8 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase HTH_16 PF12645.2 KEG11679.1 - 0.19 11.6 0.0 0.44 10.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain CENP-F_C_Rb_bdg PF10490.4 KEG11681.1 - 0.035 13.4 0.2 0.062 12.6 0.1 1.4 1 0 0 1 1 1 0 Rb-binding domain of kinetochore protein Cenp-F/LEK1 HrpA_pilin PF09589.5 KEG11682.1 - 0.012 15.9 10.5 0.062 13.7 0.0 3.2 1 1 1 2 2 2 0 HrpA pilus formation protein Ank PF00023.25 KEG11683.1 - 5.3e-32 108.0 1.2 2.3e-07 30.2 0.3 5.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.2 KEG11683.1 - 2.3e-29 101.5 0.8 4.2e-17 62.2 0.2 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEG11683.1 - 7.2e-23 80.5 1.8 2.6e-06 27.8 0.2 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEG11683.1 - 3.9e-22 76.1 1.0 6.8e-06 25.8 0.2 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 KEG11683.1 - 5.9e-21 74.0 2.2 1.5e-07 31.4 0.1 4.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) PDCD2_C PF04194.8 KEG11684.1 - 7.7e-20 71.1 0.2 7.7e-20 71.1 0.1 2.1 2 1 1 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain Zn_Tnp_IS1595 PF12760.2 KEG11684.1 - 0.36 10.6 11.6 0.7 9.7 1.2 3.2 2 2 1 3 3 3 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 KEG11684.1 - 1.4 8.9 9.5 5.1 7.1 0.1 3.5 3 0 0 3 3 3 0 Zinc ribbon domain PhnA_Zn_Ribbon PF08274.7 KEG11684.1 - 1.7 8.5 7.8 4.1 7.2 0.0 3.2 2 1 0 2 2 2 0 PhnA Zinc-Ribbon CpXC PF14353.1 KEG11684.1 - 3.3 7.6 8.9 6.3 6.7 0.1 3.1 3 1 0 3 3 3 0 CpXC protein LicD PF04991.8 KEG11685.1 - 1.2e-14 54.8 0.2 3e-08 34.0 0.1 2.1 1 1 1 2 2 2 2 LicD family 3-alpha PF03475.9 KEG11685.1 - 0.08 12.6 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 3-alpha domain Aminoglyc_resit PF10706.4 KEG11685.1 - 0.14 11.7 0.1 0.37 10.3 0.0 1.7 2 0 0 2 2 2 0 Aminoglycoside-2''-adenylyltransferase HA PF03457.9 KEG11687.1 - 0.12 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Helicase associated domain DUF791 PF05631.9 KEG11688.1 - 6.5e-108 360.5 6.6 1.1e-107 359.8 4.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 KEG11688.1 - 1.2e-20 73.5 28.4 2.3e-20 72.6 19.7 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily Mpv17_PMP22 PF04117.7 KEG11688.1 - 0.058 13.0 6.9 0.095 12.3 1.0 2.8 2 0 0 2 2 2 0 Mpv17 / PMP22 family DUF3306 PF11748.3 KEG11689.1 - 6.7 7.4 11.7 0.15 12.7 1.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3306) zf-RING_2 PF13639.1 KEG11690.1 - 6.5e-10 38.6 9.3 6.5e-10 38.6 6.5 2.6 2 1 0 2 2 2 1 Ring finger domain zf-UBP PF02148.14 KEG11690.1 - 1.5e-09 37.7 15.9 4.4e-09 36.3 11.0 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-rbx1 PF12678.2 KEG11690.1 - 5.9e-06 26.3 3.9 5.9e-06 26.3 2.7 2.4 1 1 1 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KEG11690.1 - 9.9e-06 25.1 7.9 9.9e-06 25.1 5.5 2.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KEG11690.1 - 0.0006 19.7 10.2 0.0006 19.7 7.1 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Use1 PF09753.4 KEG11690.1 - 0.0049 16.3 3.3 0.007 15.8 2.3 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 zf-C3HC4 PF00097.20 KEG11690.1 - 0.0079 15.8 9.4 0.0079 15.8 6.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Ribosomal_S7e PF01251.13 KEG11691.1 - 2.6e-68 229.2 2.0 3e-68 229.0 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e DNA_pol_B_thumb PF14791.1 KEG11692.1 - 1.2e-07 31.2 0.0 2.6e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb KIP1 PF07765.7 KEG11693.1 - 0.023 14.5 1.3 0.71 9.7 0.1 3.1 2 0 0 2 2 2 0 KIP1-like protein V_ATPase_I PF01496.14 KEG11693.1 - 0.31 8.8 5.2 0.43 8.3 3.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Dymeclin PF09742.4 KEG11694.1 - 7.3e-101 338.3 0.0 1.1e-100 337.7 0.0 1.2 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.2 KEG11694.1 - 0.041 11.5 2.1 0.34 8.5 0.0 2.3 2 1 0 2 2 2 0 High-temperature-induced dauer-formation protein DUF788 PF05620.6 KEG11695.1 - 4.6e-29 101.4 0.0 5.4e-29 101.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) SNARE PF05739.14 KEG11697.1 - 1.3e-07 31.1 1.2 3.5e-07 29.7 0.9 1.8 1 0 0 1 1 1 1 SNARE domain RmuC PF02646.11 KEG11698.1 - 0.0075 15.1 1.4 0.014 14.2 1.0 1.4 1 0 0 1 1 1 1 RmuC family DUF1664 PF07889.7 KEG11698.1 - 0.098 12.4 2.8 0.14 11.9 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) bPH_5 PF10882.3 KEG11698.1 - 0.19 11.5 0.0 0.48 10.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial PH domain KxDL PF10241.4 KEG11698.1 - 1.1 9.1 5.1 3 7.8 0.9 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF4404 PF14357.1 KEG11698.1 - 6.1 7.3 11.8 0.21 12.0 0.8 3.3 2 1 2 4 4 4 0 Domain of unknown function (DUF4404) MPC PF03650.8 KEG11700.1 - 7.4e-13 48.4 0.2 8.4e-13 48.3 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) YqbF PF14553.1 KEG11701.1 - 0.016 14.8 0.1 0.053 13.1 0.0 1.9 2 0 0 2 2 2 0 YqbF, hypothetical protein domain DUF378 PF04070.7 KEG11701.1 - 2.1 8.0 5.6 9.3 5.9 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF378) WD40 PF00400.27 KEG11702.1 - 8.4e-17 60.3 12.0 1.8e-06 27.6 0.2 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat Fucokinase PF07959.7 KEG11703.1 - 0.18 10.3 0.4 8.7 4.7 0.0 2.1 1 1 1 2 2 2 0 L-fucokinase Elf1 PF05129.8 KEG11704.1 - 4.8e-08 32.5 3.3 2.3e-07 30.4 2.3 2.0 1 1 0 1 1 1 1 Transcription elongation factor Elf1 like Tmemb_55A PF09788.4 KEG11704.1 - 0.017 14.2 1.0 0.026 13.6 0.7 1.2 1 0 0 1 1 1 0 Transmembrane protein 55A Fer4_17 PF13534.1 KEG11704.1 - 0.022 15.1 0.5 0.075 13.3 0.1 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain Lar_restr_allev PF14354.1 KEG11704.1 - 0.069 13.4 0.4 0.2 11.9 0.3 1.8 1 0 0 1 1 1 0 Restriction alleviation protein Lar Fer4_8 PF13183.1 KEG11704.1 - 0.16 12.0 5.8 0.1 12.6 0.8 2.5 1 1 2 3 3 3 0 4Fe-4S dicluster domain Ribosomal_60s PF00428.14 KEG11704.1 - 0.23 11.8 8.6 0.45 10.9 6.0 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Fer4_4 PF12800.2 KEG11704.1 - 4.8 7.7 6.8 2.4 8.7 0.6 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Elf1 PF05129.8 KEG11705.1 - 3e-21 74.8 0.0 4e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zinc_ribbon_4 PF13717.1 KEG11705.1 - 0.013 15.2 0.9 0.034 13.8 0.6 1.7 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 KEG11705.1 - 0.021 14.3 0.8 0.057 13.0 0.6 1.7 1 0 0 1 1 1 0 zinc-ribbon domain FdhE PF04216.7 KEG11705.1 - 0.044 13.5 0.8 0.13 11.9 0.3 1.8 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation Zn_Tnp_IS1 PF03811.8 KEG11705.1 - 0.12 11.9 1.7 0.22 11.0 1.2 1.4 1 0 0 1 1 1 0 InsA N-terminal domain zf-Sec23_Sec24 PF04810.10 KEG11705.1 - 0.79 9.3 3.1 3.3 7.3 0.0 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger DEAD PF00270.24 KEG11706.1 - 1.7e-31 109.0 0.2 1e-15 57.6 0.0 3.2 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KEG11706.1 - 2.4e-13 49.7 0.0 5.5e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEG11706.1 - 3.3e-09 36.8 0.0 7.3e-08 32.4 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KEG11706.1 - 0.004 17.3 0.2 3.9 7.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain CDC45 PF02724.9 KEG11706.1 - 0.086 10.8 3.1 0.23 9.4 2.2 1.7 1 0 0 1 1 1 0 CDC45-like protein TruD PF01142.13 KEG11708.1 - 1.2e-22 80.1 0.0 1.6e-19 69.8 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) SCO1-SenC PF02630.9 KEG11710.1 - 1.1e-29 103.2 0.0 3e-28 98.5 0.0 2.1 1 1 0 1 1 1 1 SCO1/SenC GRAM PF02893.15 KEG11711.1 - 0.049 13.1 0.0 0.091 12.2 0.0 1.3 1 0 0 1 1 1 0 GRAM domain PH_BEACH PF14844.1 KEG11711.1 - 0.12 12.1 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 PH domain associated with Beige/BEACH AAA PF00004.24 KEG11712.1 - 1.8e-51 173.8 0.0 8.6e-36 123.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KEG11712.1 - 1e-12 48.9 0.3 4.4e-06 27.5 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KEG11712.1 - 4.9e-09 36.4 1.6 0.015 15.4 0.5 4.3 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KEG11712.1 - 6.4e-09 36.2 0.0 0.0014 18.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KEG11712.1 - 1.1e-08 34.9 0.0 0.00045 19.9 0.0 2.8 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KEG11712.1 - 1.2e-07 31.3 0.1 0.0033 17.1 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain TIP49 PF06068.8 KEG11712.1 - 1.9e-07 30.1 0.1 0.0076 15.0 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_33 PF13671.1 KEG11712.1 - 7.6e-07 29.0 0.0 0.019 14.8 0.0 3.1 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.1 KEG11712.1 - 3.3e-06 27.1 0.1 0.081 12.9 0.0 3.3 2 1 0 2 2 2 2 AAA ATPase domain Mg_chelatase PF01078.16 KEG11712.1 - 5.3e-05 22.4 0.1 0.005 16.0 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 KEG11712.1 - 0.00012 21.9 0.0 0.06 13.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 KEG11712.1 - 0.00013 21.5 0.0 0.53 9.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KEG11712.1 - 0.00017 21.0 0.1 0.049 13.0 0.0 3.3 4 0 0 4 4 4 1 IstB-like ATP binding protein KTI12 PF08433.5 KEG11712.1 - 0.00021 20.6 0.0 0.071 12.3 0.0 2.4 2 0 0 2 2 2 1 Chromatin associated protein KTI12 RNA_helicase PF00910.17 KEG11712.1 - 0.00051 20.1 0.0 0.97 9.6 0.0 2.5 2 0 0 2 2 2 2 RNA helicase Zeta_toxin PF06414.7 KEG11712.1 - 0.00057 19.0 0.1 0.4 9.7 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin DUF2075 PF09848.4 KEG11712.1 - 0.00092 18.2 0.2 0.25 10.2 0.0 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.21 KEG11712.1 - 0.001 18.5 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_2 PF07724.9 KEG11712.1 - 0.0012 18.8 0.0 0.0077 16.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) CDC48_N PF02359.13 KEG11712.1 - 0.0012 18.7 0.0 0.0028 17.5 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain NACHT PF05729.7 KEG11712.1 - 0.0016 18.1 0.1 4.6 6.8 0.1 3.4 2 1 0 2 2 2 0 NACHT domain RuvB_N PF05496.7 KEG11712.1 - 0.0021 17.1 0.0 0.16 11.0 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Sigma54_activ_2 PF14532.1 KEG11712.1 - 0.0029 17.6 0.0 1.8 8.5 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_25 PF13481.1 KEG11712.1 - 0.009 15.4 3.6 6.7 6.0 0.0 3.8 3 1 1 4 4 4 0 AAA domain PhoH PF02562.11 KEG11712.1 - 0.01 15.0 0.1 0.76 8.9 0.1 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_28 PF13521.1 KEG11712.1 - 0.015 15.3 0.0 2.6 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KEG11712.1 - 0.019 14.5 0.1 9.1 5.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.1 KEG11712.1 - 0.022 14.3 0.1 1.2 8.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 KEG11712.1 - 0.027 13.5 0.0 1 8.4 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_11 PF13086.1 KEG11712.1 - 0.036 13.6 0.0 2.8 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KEG11712.1 - 0.046 14.0 0.1 5.4 7.3 0.0 2.9 2 1 1 3 3 3 0 ABC transporter Thymidylate_kin PF02223.12 KEG11712.1 - 0.063 12.6 0.0 2.7 7.3 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase CDC48_2 PF02933.12 KEG11712.1 - 0.11 12.1 0.4 0.34 10.5 0.0 2.0 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 SKI PF01202.17 KEG11712.1 - 0.11 12.3 0.0 9 6.1 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase Cytidylate_kin2 PF13189.1 KEG11712.1 - 0.17 11.7 0.0 0.51 10.2 0.0 1.9 2 0 0 2 2 1 0 Cytidylate kinase-like family NB-ARC PF00931.17 KEG11712.1 - 0.22 10.3 0.3 12 4.6 0.2 2.5 3 0 0 3 3 3 0 NB-ARC domain TTL PF03133.10 KEG11713.1 - 8e-56 189.1 0.0 1.2e-55 188.5 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 KEG11713.1 - 5.6e-05 22.0 0.0 9.9e-05 21.2 0.0 1.3 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 KEG11713.1 - 0.0028 17.4 0.1 0.019 14.6 0.0 2.5 3 1 0 4 4 4 1 ATP-grasp domain Tubulin_3 PF14881.1 KEG11714.1 - 0.0027 17.1 0.0 0.0063 15.9 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 KEG11714.1 - 0.0034 17.4 0.1 0.0081 16.1 0.1 1.8 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Prefoldin_2 PF01920.15 KEG11717.1 - 1.5e-19 69.7 3.1 1.8e-19 69.4 2.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit SlyX PF04102.7 KEG11717.1 - 0.00076 19.8 1.0 0.00076 19.8 0.7 2.0 2 0 0 2 2 2 1 SlyX DivIVA PF05103.8 KEG11717.1 - 0.011 15.8 7.3 0.84 9.6 0.2 2.1 2 0 0 2 2 2 0 DivIVA protein AKNA PF12443.3 KEG11717.1 - 0.02 14.9 1.7 1.6 8.7 0.0 2.2 2 0 0 2 2 2 0 AT-hook-containing transcription factor TPD52 PF04201.10 KEG11717.1 - 0.039 13.6 0.4 0.078 12.7 0.3 1.5 1 0 0 1 1 1 0 Tumour protein D52 family Prefoldin PF02996.12 KEG11717.1 - 0.052 13.2 1.4 0.072 12.7 0.1 1.8 2 0 0 2 2 2 0 Prefoldin subunit CotJB PF12652.2 KEG11717.1 - 0.054 13.5 0.6 0.13 12.3 0.1 1.8 2 0 0 2 2 2 0 CotJB protein Zwint PF15556.1 KEG11717.1 - 0.071 12.3 6.0 0.027 13.7 1.2 1.9 2 0 0 2 2 2 0 ZW10 interactor Spectrin PF00435.16 KEG11717.1 - 0.08 13.2 3.6 0.095 12.9 0.9 1.9 1 1 1 2 2 2 0 Spectrin repeat NBP1 PF08537.5 KEG11717.1 - 0.1 11.7 0.3 0.12 11.5 0.2 1.1 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 DUF3418 PF11898.3 KEG11717.1 - 0.11 10.9 2.0 0.12 10.7 1.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) ALIX_LYPXL_bnd PF13949.1 KEG11717.1 - 0.11 11.4 5.8 0.17 10.8 0.2 2.0 1 1 0 2 2 2 0 ALIX V-shaped domain binding to HIV Nup54 PF13874.1 KEG11717.1 - 0.13 11.9 4.9 1.1 8.9 0.4 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 DUF972 PF06156.8 KEG11717.1 - 0.15 12.3 4.7 5.6 7.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) CK2S PF15011.1 KEG11717.1 - 0.16 11.7 2.4 0.24 11.1 1.7 1.2 1 0 0 1 1 1 0 Casein Kinase 2 substrate DUF1875 PF08961.5 KEG11717.1 - 0.18 11.1 1.9 0.17 11.2 0.3 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1875) NTR2 PF15458.1 KEG11717.1 - 0.19 10.9 4.0 0.68 9.1 0.1 2.1 2 0 0 2 2 2 0 Nineteen complex-related protein 2 ATG16 PF08614.6 KEG11717.1 - 0.2 11.4 5.9 3.4 7.4 0.4 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Tropomyosin_1 PF12718.2 KEG11717.1 - 0.21 11.4 7.2 1.4 8.7 0.5 2.2 2 0 0 2 2 2 0 Tropomyosin like IncA PF04156.9 KEG11717.1 - 0.21 11.1 10.2 2.3 7.7 7.1 2.0 1 1 0 1 1 1 0 IncA protein TPR_20 PF14561.1 KEG11717.1 - 0.22 11.6 1.6 0.24 11.5 0.1 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DASH_Dad3 PF08656.5 KEG11717.1 - 0.31 10.7 5.1 1.3 8.7 0.6 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad3 NYD-SP28_assoc PF14775.1 KEG11717.1 - 0.36 10.5 3.1 6.8 6.4 0.4 2.3 2 0 0 2 2 2 0 Sperm tail C-terminal domain BLOC1_2 PF10046.4 KEG11717.1 - 0.4 10.8 3.2 5.3 7.2 0.1 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_1 PF00170.16 KEG11717.1 - 0.46 10.4 6.6 0.94 9.4 0.8 2.5 2 0 0 2 2 2 0 bZIP transcription factor Cep57_CLD_2 PF14197.1 KEG11717.1 - 1.5 8.8 10.4 0.78 9.7 2.8 2.2 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 FTA4 PF13093.1 KEG11717.1 - 1.5 8.2 7.1 1.9 7.8 0.9 2.0 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 FliJ PF02050.11 KEG11717.1 - 1.6 8.8 9.9 1.5 8.8 0.7 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein YlqD PF11068.3 KEG11717.1 - 5.9 6.9 8.3 0.96 9.4 2.0 1.9 1 1 1 2 2 2 0 YlqD protein Spc24 PF08286.6 KEG11717.1 - 7.1 6.3 6.8 2.3 7.9 0.6 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 TYW3 PF02676.9 KEG11718.1 - 3.6e-39 134.0 0.0 6.8e-39 133.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase TYW3 AAA_33 PF13671.1 KEG11719.1 - 4e-05 23.5 0.0 0.00015 21.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEG11719.1 - 0.0011 19.7 0.0 0.0021 18.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KEG11719.1 - 0.0015 17.7 0.0 0.0056 15.7 0.0 1.8 1 1 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 KEG11719.1 - 0.014 15.3 0.1 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain APS_kinase PF01583.15 KEG11719.1 - 0.05 13.2 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.1 KEG11719.1 - 0.24 11.7 0.2 0.67 10.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain KOG2701 PF09762.4 KEG11720.1 - 7.6e-38 130.3 0.0 7.6e-38 130.3 0.0 3.3 2 2 1 3 3 3 1 Coiled-coil domain-containing protein (DUF2037) DUF3492 PF11997.3 KEG11720.1 - 0.093 12.2 4.4 0.25 10.8 3.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) zf-DHHC PF01529.15 KEG11721.1 - 1.7e-31 108.9 0.6 1.7e-31 108.9 0.4 2.2 2 1 0 2 2 2 1 DHHC palmitoyltransferase Voltage_CLC PF00654.15 KEG11721.1 - 0.0044 16.0 1.9 0.0044 16.0 1.3 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel PH PF00169.24 KEG11722.1 - 2.8e-10 40.3 0.1 9.2e-10 38.6 0.0 2.0 2 0 0 2 2 2 1 PH domain PRKCSH-like PF12999.2 KEG11727.1 - 8.4e-12 45.0 1.2 3.8e-06 26.6 0.0 2.8 3 0 0 3 3 3 2 Glucosidase II beta subunit-like Ldl_recept_a PF00057.13 KEG11727.1 - 0.038 13.9 0.3 0.038 13.9 0.2 2.5 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A Pro_CA PF00484.14 KEG11729.1 - 1.2e-39 135.7 0.0 1.6e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase DUF89 PF01937.14 KEG11730.1 - 3.2e-46 157.7 0.0 5.5e-30 104.3 0.0 4.4 4 0 0 4 4 4 4 Protein of unknown function DUF89 Put_Phosphatase PF06888.7 KEG11730.1 - 6e-37 127.0 0.1 3.1e-36 124.7 0.0 2.1 2 0 0 2 2 2 1 Putative Phosphatase HAD PF12710.2 KEG11730.1 - 1.3e-06 28.7 0.0 5e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4355 PF14265.1 KEG11731.1 - 9.4 6.2 12.7 23 4.9 8.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) RRM_3 PF08777.6 KEG11732.1 - 0.26 11.1 0.1 0.26 11.1 0.1 2.6 3 0 0 3 3 3 0 RNA binding motif Pkinase PF00069.20 KEG11733.1 - 1.5e-54 184.9 0.0 2.7e-54 184.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG11733.1 - 4.4e-35 121.0 0.0 8.7e-35 120.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KEG11733.1 - 1.9e-09 37.4 0.1 6e-09 35.9 0.1 1.9 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 KEG11733.1 - 1.4e-05 24.2 0.0 3.5e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Kinase-like PAS PF00989.19 KEG11733.1 - 0.023 14.4 0.0 0.098 12.4 0.0 2.0 2 0 0 2 2 2 0 PAS fold Prenyltrans_2 PF13249.1 KEG11734.1 - 2.2e-21 76.3 0.1 2.7e-09 37.4 0.0 5.4 4 1 1 5 5 5 5 Prenyltransferase-like Prenyltrans PF00432.16 KEG11734.1 - 4e-20 71.0 8.8 2.9e-05 23.5 0.0 6.0 5 1 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 KEG11734.1 - 2.7e-18 65.9 0.2 2.9e-06 27.2 0.2 5.6 3 1 1 5 5 5 3 Prenyltransferase-like Pec_lyase PF09492.5 KEG11734.1 - 1.5e-08 34.1 0.0 0.0077 15.4 0.0 3.7 2 1 1 3 3 3 3 Pectic acid lyase DUF823 PF05689.6 KEG11735.1 - 0.015 14.6 0.0 1.8 7.8 0.0 2.4 2 0 0 2 2 2 0 Salmonella repeat of unknown function (DUF823) DUF601 PF04642.7 KEG11735.1 - 1.3 8.3 5.5 1.7 7.9 3.1 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF601 PSP1 PF04468.7 KEG11736.1 - 8e-07 28.9 0.0 1.5e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Mito_fiss_reg PF05308.6 KEG11736.1 - 0.18 11.1 3.5 0.57 9.5 2.4 1.8 1 0 0 1 1 1 0 Mitochondrial fission regulator Tropomyosin PF00261.15 KEG11737.1 - 0.0039 16.3 0.2 0.01 14.9 0.1 1.6 1 0 0 1 1 1 1 Tropomyosin Spore-coat_CotZ PF10612.4 KEG11737.1 - 0.49 10.2 2.5 11 5.8 0.1 2.5 2 1 0 2 2 2 0 Spore coat protein Z HlyIII PF03006.15 KEG11738.1 - 9.7e-51 172.3 29.0 1.2e-50 172.0 20.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related NfeD PF01957.13 KEG11738.1 - 7.7 6.6 12.1 0.24 11.5 0.3 3.1 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding HlyIII PF03006.15 KEG11739.1 - 6.1e-57 192.5 29.9 7.2e-57 192.3 20.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF3817 PF12823.2 KEG11739.1 - 2.8 8.4 14.6 0.32 11.4 2.5 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3817) DUF4389 PF14333.1 KEG11739.1 - 3 7.5 7.1 1.6 8.5 0.2 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4389) DUF962 PF06127.6 KEG11739.1 - 4.1 7.3 8.5 16 5.4 5.9 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF962) PCIF1_WW PF12237.3 KEG11740.1 - 1.2e-48 164.7 0.0 2.2e-48 163.8 0.0 1.4 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain KTI12 PF08433.5 KEG11741.1 - 2.5e-05 23.6 0.4 0.054 12.7 0.0 3.4 2 1 1 3 3 3 2 Chromatin associated protein KTI12 AAA_18 PF13238.1 KEG11741.1 - 4.1e-05 23.8 1.4 0.00013 22.3 0.2 2.3 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KEG11741.1 - 0.00012 22.0 5.0 0.00017 21.5 1.2 2.8 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KEG11741.1 - 0.006 17.4 0.4 0.017 15.9 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEG11741.1 - 0.01 15.8 5.1 0.056 13.4 0.4 3.0 2 1 0 3 3 3 0 AAA ATPase domain Zeta_toxin PF06414.7 KEG11741.1 - 0.02 13.9 0.1 0.064 12.3 0.1 1.8 2 0 0 2 2 2 0 Zeta toxin APS_kinase PF01583.15 KEG11741.1 - 0.024 14.3 0.3 0.4 10.3 0.0 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_19 PF13245.1 KEG11741.1 - 0.05 13.3 0.3 0.18 11.5 0.1 2.0 2 0 0 2 2 2 0 Part of AAA domain AAA_22 PF13401.1 KEG11741.1 - 0.074 13.2 2.6 0.92 9.6 0.1 2.6 3 0 0 3 3 3 0 AAA domain AAA PF00004.24 KEG11741.1 - 0.15 12.3 0.0 0.37 11.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF621 PF04789.10 KEG11742.1 - 0.037 13.0 0.1 0.062 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF621) EMP24_GP25L PF01105.19 KEG11743.1 - 3.5e-15 56.1 0.0 4.2e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD HEAT_2 PF13646.1 KEG11744.1 - 0.0023 18.1 0.3 0.036 14.3 0.0 2.7 2 1 0 2 2 2 1 HEAT repeats Arm PF00514.18 KEG11744.1 - 0.025 14.3 0.0 0.099 12.5 0.0 2.1 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat DUF2094 PF09867.4 KEG11744.1 - 0.055 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2094) Peptidase_M55 PF04951.8 KEG11744.1 - 0.087 12.0 0.0 13 4.9 0.0 2.1 2 0 0 2 2 2 0 D-aminopeptidase HEAT_EZ PF13513.1 KEG11744.1 - 0.57 10.7 3.1 26 5.4 0.1 3.1 3 0 0 3 3 3 0 HEAT-like repeat CAP_C PF08603.6 KEG11745.1 - 2.2e-47 160.3 9.4 3.2e-47 159.8 6.5 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal CAP_N PF01213.14 KEG11745.1 - 1.6e-13 50.6 7.9 3e-13 49.7 5.4 1.5 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal TBCC PF07986.7 KEG11745.1 - 0.04 13.3 3.2 0.07 12.5 2.2 1.4 1 0 0 1 1 1 0 Tubulin binding cofactor C Mito_fiss_reg PF05308.6 KEG11745.1 - 2.1 7.6 18.6 0.24 10.7 9.6 1.8 2 1 0 2 2 2 0 Mitochondrial fission regulator CesT PF05932.8 KEG11746.1 - 6.9e-17 61.3 0.0 1.5e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Tir chaperone protein (CesT) family Adaptin_N PF01602.15 KEG11747.1 - 4.9e-75 252.8 1.6 6.3e-75 252.4 1.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region B2-adapt-app_C PF09066.5 KEG11747.1 - 6.9e-18 64.5 0.0 1.6e-17 63.3 0.0 1.7 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain Cnd1 PF12717.2 KEG11747.1 - 7e-10 39.0 1.9 1.1e-09 38.4 0.1 2.3 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KEG11747.1 - 3.3e-07 30.4 0.2 0.00054 20.1 0.0 4.3 3 1 1 4 4 4 1 HEAT repeats HEAT PF02985.17 KEG11747.1 - 1.8e-05 24.4 1.8 0.0096 15.9 0.0 4.9 4 0 0 4 4 4 1 HEAT repeat CLASP_N PF12348.3 KEG11747.1 - 0.0064 15.8 0.0 0.039 13.2 0.0 2.3 2 0 0 2 2 2 1 CLASP N terminal HEAT_EZ PF13513.1 KEG11747.1 - 0.0086 16.5 0.8 0.83 10.2 0.0 4.0 3 1 1 4 4 4 1 HEAT-like repeat DUF3554 PF12074.3 KEG11747.1 - 0.013 14.9 0.0 0.96 8.8 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3554) FRQ PF09421.5 KEG11747.1 - 2.9 5.5 4.7 4.1 5.0 3.3 1.1 1 0 0 1 1 1 0 Frequency clock protein LPP PF04728.8 KEG11748.1 - 0.028 14.2 0.3 0.34 10.7 0.1 2.9 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Baculo_PEP_C PF04513.7 KEG11748.1 - 0.11 12.3 0.1 0.11 12.3 0.1 4.0 4 2 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus NBP1 PF08537.5 KEG11748.1 - 1 8.5 10.0 2.6 7.1 2.8 2.7 2 0 0 2 2 2 0 Fungal Nap binding protein NBP1 DUF1664 PF07889.7 KEG11748.1 - 1.1 9.0 3.8 8.7 6.1 0.1 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF2730 PF10805.3 KEG11748.1 - 2.2 8.0 11.0 0.63 9.8 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2730) EF-hand_7 PF13499.1 KEG11749.1 - 0.01 15.9 0.0 0.014 15.5 0.0 1.1 1 0 0 1 1 1 0 EF-hand domain pair Gpi1 PF05024.10 KEG11750.1 - 6e-36 123.9 6.8 6e-36 123.9 4.7 2.1 3 0 0 3 3 3 1 N-acetylglucosaminyl transferase component (Gpi1) Pkinase PF00069.20 KEG11751.1 - 2.6e-74 249.6 0.0 3.4e-74 249.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG11751.1 - 1.1e-40 139.4 0.0 1.5e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG11751.1 - 2.4e-06 26.7 0.0 5.4e-06 25.5 0.0 1.5 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 KEG11751.1 - 0.00058 19.2 0.4 0.004 16.5 0.3 2.0 1 1 1 2 2 2 1 RIO1 family Kdo PF06293.9 KEG11751.1 - 0.0086 15.1 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEG11751.1 - 0.0095 15.6 0.0 0.025 14.3 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF1684 PF07920.6 KEG11751.1 - 0.039 13.8 0.0 0.083 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1684) YukC PF10140.4 KEG11751.1 - 0.21 10.1 0.0 0.29 9.6 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC PPR_2 PF13041.1 KEG11752.1 - 5.2e-06 26.3 0.4 0.15 12.0 0.0 4.4 4 1 1 5 5 5 2 PPR repeat family BTAD PF03704.12 KEG11752.1 - 0.00013 22.3 8.3 0.00041 20.6 5.8 1.9 1 0 0 1 1 1 1 Bacterial transcriptional activator domain TPR_11 PF13414.1 KEG11752.1 - 0.0024 17.4 3.9 0.005 16.4 1.2 2.7 3 0 0 3 3 3 1 TPR repeat PPR PF01535.15 KEG11752.1 - 0.0035 17.2 0.2 2.9 8.0 0.0 4.0 4 0 0 4 4 4 1 PPR repeat TPR_2 PF07719.12 KEG11752.1 - 0.015 15.1 0.8 5.8 7.0 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2893 PF11459.3 KEG11752.1 - 0.016 14.9 0.4 0.14 11.9 0.1 2.7 3 0 0 3 3 3 0 Protein of unknwon function (DUF2893) TPR_14 PF13428.1 KEG11752.1 - 0.02 15.5 6.0 0.19 12.4 0.1 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat PPR_3 PF13812.1 KEG11752.1 - 0.83 10.0 5.6 16 6.1 0.1 4.9 4 1 1 5 5 5 0 Pentatricopeptide repeat domain TPR_19 PF14559.1 KEG11752.1 - 7.6 6.9 7.2 4.7 7.6 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Nol1_Nop2_Fmu PF01189.12 KEG11753.1 - 3.8e-19 69.1 0.0 1.6e-06 27.6 0.0 4.0 4 0 0 4 4 4 3 NOL1/NOP2/sun family PCMT PF01135.14 KEG11753.1 - 0.043 13.3 0.0 0.35 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) dCMP_cyt_deam_1 PF00383.17 KEG11754.1 - 3.4 7.3 10.7 1.9e+02 1.7 7.4 3.0 1 1 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region Radial_spoke PF04712.7 KEG11761.1 - 5.9e-08 31.8 27.4 2.9e-07 29.6 0.0 3.1 2 1 0 2 2 1 1 Radial spokehead-like protein TRAP_alpha PF03896.11 KEG11761.1 - 0.001 18.1 0.3 0.0014 17.7 0.2 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit CobT PF06213.7 KEG11761.1 - 0.008 15.3 8.2 0.021 13.9 6.0 1.4 2 0 0 2 2 2 1 Cobalamin biosynthesis protein CobT HNOBA PF07701.9 KEG11761.1 - 0.018 14.2 0.0 0.025 13.7 0.0 1.1 1 0 0 1 1 1 0 Heme NO binding associated Spore_coat_CotO PF14153.1 KEG11761.1 - 0.019 14.4 9.0 0.027 13.9 6.2 1.1 1 0 0 1 1 1 0 Spore coat protein CotO BNR PF02012.15 KEG11761.1 - 0.086 12.7 0.7 0.21 11.5 0.5 1.7 1 0 0 1 1 1 0 BNR/Asp-box repeat Prog_receptor PF02161.10 KEG11761.1 - 0.12 11.2 7.5 0.16 10.7 5.2 1.1 1 0 0 1 1 1 0 Progesterone receptor TLP-20 PF06088.6 KEG11761.1 - 0.23 11.1 7.8 6.8 6.3 5.3 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DDHD PF02862.12 KEG11761.1 - 0.28 10.9 2.7 0.4 10.4 1.9 1.1 1 0 0 1 1 1 0 DDHD domain Nop14 PF04147.7 KEG11761.1 - 0.42 8.4 13.3 0.55 8.0 9.2 1.0 1 0 0 1 1 1 0 Nop14-like family Tim54 PF11711.3 KEG11761.1 - 0.68 8.4 8.7 0.94 7.9 6.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 MCPVI PF02993.9 KEG11761.1 - 0.83 9.7 2.6 1.3 9.1 1.8 1.3 1 0 0 1 1 1 0 Minor capsid protein VI CDC45 PF02724.9 KEG11761.1 - 0.87 7.5 9.4 1.2 7.0 6.5 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.6 KEG11761.1 - 1.2 7.1 3.9 1.5 6.8 2.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sigma70_ner PF04546.8 KEG11761.1 - 1.8 8.1 13.4 2.6 7.5 9.3 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region PBP1_TM PF14812.1 KEG11761.1 - 1.8 8.8 9.5 3.2 8.1 6.6 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal YqfQ PF14181.1 KEG11761.1 - 3.5 7.6 10.4 5.2 7.0 7.2 1.2 1 0 0 1 1 1 0 YqfQ-like protein HSP90 PF00183.13 KEG11761.1 - 5.3 5.3 15.5 7.3 4.8 10.8 1.1 1 0 0 1 1 1 0 Hsp90 protein RR_TM4-6 PF06459.7 KEG11761.1 - 7.8 6.3 13.7 11 5.8 9.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM176 PF14851.1 KEG11761.1 - 9 5.9 9.0 14 5.3 6.3 1.2 1 0 0 1 1 1 0 FAM176 family DUF3608 PF12257.3 KEG11762.1 - 7.2e-18 64.4 0.2 5.3e-10 38.6 0.0 3.3 3 0 0 3 3 3 3 Protein of unknown function (DUF3608) WD40 PF00400.27 KEG11763.1 - 2.4e-07 30.3 2.2 0.0003 20.5 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF3040 PF11239.3 KEG11764.1 - 0.46 10.5 4.4 0.9 9.6 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) APG6 PF04111.7 KEG11764.1 - 1.6 7.6 10.0 2.2 7.2 6.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 PKD_channel PF08016.7 KEG11765.1 - 0.0011 17.4 14.1 0.0011 17.4 9.8 1.7 1 1 1 2 2 2 1 Polycystin cation channel DUF1212 PF06738.7 KEG11765.1 - 1.1 8.7 7.8 3.1 7.2 4.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1212) Activator_LAG-3 PF11498.3 KEG11766.1 - 0.58 8.8 13.8 1.1 7.9 9.6 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 PSK PF06404.7 KEG11767.1 - 0.28 11.9 1.5 9.6 7.0 0.4 2.7 3 0 0 3 3 3 0 Phytosulfokine precursor protein (PSK) DUF4577 PF15145.1 KEG11768.1 - 0.052 13.4 0.0 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) Internalin_N PF12354.3 KEG11768.1 - 0.19 11.3 0.7 0.41 10.3 0.5 1.5 1 0 0 1 1 1 0 Bacterial adhesion/invasion protein N terminal DUF2408 PF10303.4 KEG11770.1 - 0.00032 20.8 0.5 0.00036 20.6 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2408) BicD PF09730.4 KEG11770.1 - 0.00038 18.9 0.4 0.00043 18.7 0.2 1.0 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D Mnd1 PF03962.10 KEG11770.1 - 0.00061 19.5 0.7 0.00071 19.2 0.5 1.1 1 0 0 1 1 1 1 Mnd1 family DUF342 PF03961.8 KEG11770.1 - 0.0043 15.5 0.5 0.0055 15.1 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF342) ERM PF00769.14 KEG11770.1 - 0.006 16.1 1.0 0.0063 16.0 0.7 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family CorA PF01544.13 KEG11770.1 - 0.011 14.8 1.4 0.012 14.6 0.9 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Tropomyosin PF00261.15 KEG11770.1 - 0.011 14.8 4.4 0.013 14.6 3.1 1.1 1 0 0 1 1 1 0 Tropomyosin CCDC155 PF14662.1 KEG11770.1 - 0.013 15.1 1.9 0.014 15.0 1.3 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 APG6 PF04111.7 KEG11770.1 - 0.013 14.5 0.8 0.016 14.3 0.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3422 PF11902.3 KEG11770.1 - 0.013 14.3 1.1 0.016 14.1 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3422) DUF4140 PF13600.1 KEG11770.1 - 0.015 15.7 1.3 0.025 15.0 0.9 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Troponin PF00992.15 KEG11770.1 - 0.022 14.8 1.2 0.028 14.4 0.9 1.1 1 0 0 1 1 1 0 Troponin IncA PF04156.9 KEG11770.1 - 0.033 13.7 2.1 0.038 13.5 1.4 1.1 1 0 0 1 1 1 0 IncA protein Med4 PF10018.4 KEG11770.1 - 0.038 13.3 1.4 0.04 13.3 1.0 1.1 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 TPR_MLP1_2 PF07926.7 KEG11770.1 - 0.04 13.6 2.0 0.054 13.2 1.4 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF972 PF06156.8 KEG11770.1 - 0.044 14.1 0.9 0.053 13.8 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF4530 PF15039.1 KEG11770.1 - 0.056 13.3 2.3 0.11 12.4 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) TBCA PF02970.11 KEG11770.1 - 0.058 13.4 1.6 0.071 13.1 1.1 1.1 1 0 0 1 1 1 0 Tubulin binding cofactor A ADIP PF11559.3 KEG11770.1 - 0.069 13.0 2.4 0.089 12.6 1.6 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Baculo_PEP_C PF04513.7 KEG11770.1 - 0.07 12.9 1.0 0.14 12.0 0.6 1.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1515 PF07439.6 KEG11770.1 - 0.073 12.8 1.3 0.09 12.6 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) V_ATPase_I PF01496.14 KEG11770.1 - 0.089 10.6 0.9 0.099 10.4 0.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Seryl_tRNA_N PF02403.17 KEG11770.1 - 0.13 12.2 4.5 0.5 10.4 2.1 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FimP PF09766.4 KEG11770.1 - 0.13 11.2 0.8 0.17 10.9 0.6 1.0 1 0 0 1 1 1 0 Fms-interacting protein TEX12 PF15219.1 KEG11770.1 - 0.17 11.8 0.8 0.24 11.3 0.6 1.2 1 0 0 1 1 1 0 Testis-expressed 12 DUF2205 PF10224.4 KEG11770.1 - 0.21 11.1 2.6 0.32 10.5 0.9 1.9 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) Mitofilin PF09731.4 KEG11770.1 - 0.22 10.1 2.9 0.26 9.9 2.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF1664 PF07889.7 KEG11770.1 - 0.27 11.0 1.9 0.47 10.2 1.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DivIC PF04977.10 KEG11770.1 - 0.29 10.6 2.3 0.38 10.2 1.6 1.3 1 0 0 1 1 1 0 Septum formation initiator Cortex-I_coil PF09304.5 KEG11770.1 - 0.3 11.1 5.0 0.48 10.4 3.4 1.4 1 1 0 1 1 1 0 Cortexillin I, coiled coil Cauli_AT PF03233.8 KEG11770.1 - 0.47 10.1 2.3 0.64 9.7 1.5 1.3 1 1 0 1 1 1 0 Aphid transmission protein Spc24 PF08286.6 KEG11770.1 - 0.71 9.5 3.8 1.2 8.8 2.6 1.4 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DUF3618 PF12277.3 KEG11770.1 - 3.2 7.8 7.2 19 5.3 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3618) SRP19 PF01922.12 KEG11771.1 - 9.9e-21 74.1 0.0 1.5e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein PK PF00224.16 KEG11772.1 - 5e-162 538.3 0.8 6.3e-162 538.0 0.6 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 KEG11772.1 - 4.2e-25 87.5 2.1 7.8e-25 86.7 0.1 2.5 4 0 0 4 4 4 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 KEG11772.1 - 1.2e-05 24.3 0.8 6.4e-05 21.9 0.7 2.1 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family EMP70 PF02990.11 KEG11774.1 - 5.5e-99 331.9 18.1 3e-87 293.2 10.4 2.4 2 1 1 3 3 3 2 Endomembrane protein 70 MIP PF00230.15 KEG11775.1 - 6.2e-58 195.9 7.0 9.4e-58 195.3 4.8 1.2 1 0 0 1 1 1 1 Major intrinsic protein DUF1275 PF06912.6 KEG11775.1 - 0.28 10.3 0.0 0.28 10.3 0.0 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1275) ThiW PF09512.5 KEG11775.1 - 0.48 10.2 7.0 1.1 9.0 0.2 2.4 2 0 0 2 2 2 0 Thiamine-precursor transporter protein (ThiW) WD40 PF00400.27 KEG11776.1 - 9.9e-36 120.3 10.0 2.1e-08 33.7 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KEG11776.1 - 0.0017 17.8 0.0 0.65 9.5 0.0 3.6 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain BAF1_ABF1 PF04684.8 KEG11776.1 - 1.1 7.9 7.9 1.8 7.3 5.5 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4596 PF15363.1 KEG11777.1 - 0.043 13.7 0.3 0.043 13.7 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) SNARE PF05739.14 KEG11778.1 - 1.1e-14 53.8 0.5 1.1e-14 53.8 0.3 3.2 4 0 0 4 4 4 1 SNARE domain HsbA PF12296.3 KEG11778.1 - 0.031 14.1 0.2 0.11 12.4 0.2 1.9 1 0 0 1 1 1 0 Hydrophobic surface binding protein A Syntaxin PF00804.20 KEG11778.1 - 0.24 11.5 11.7 0.063 13.4 4.2 2.7 2 2 0 2 2 2 0 Syntaxin TMF_TATA_bd PF12325.3 KEG11778.1 - 0.27 10.9 11.2 1.6 8.4 1.0 3.2 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF1178 PF06676.6 KEG11778.1 - 0.33 11.1 3.2 0.32 11.1 0.6 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1178) Baculo_PEP_C PF04513.7 KEG11778.1 - 0.45 10.3 8.8 1.4 8.7 0.5 3.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF883 PF05957.8 KEG11778.1 - 0.82 10.1 12.2 0.057 13.8 1.4 3.1 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) FliD_N PF02465.13 KEG11778.1 - 0.9 9.9 7.1 0.57 10.5 1.4 3.1 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Allexi_40kDa PF05549.6 KEG11778.1 - 2.7 7.2 8.2 0.35 10.1 0.4 2.6 2 1 0 3 3 3 0 Allexivirus 40kDa protein Vac_Fusion PF02346.11 KEG11778.1 - 5.9 6.3 6.6 11 5.5 0.3 2.9 3 0 0 3 3 3 0 Chordopoxvirus fusion protein XG_FTase PF03254.8 KEG11781.1 - 2.4e-15 56.0 3.0 8.9e-07 27.7 0.0 3.1 2 1 0 2 2 2 2 Xyloglucan fucosyltransferase WD40 PF00400.27 KEG11783.1 - 0.0033 17.2 1.4 34 4.5 0.0 4.8 4 1 0 4 4 4 2 WD domain, G-beta repeat PEN-2 PF10251.4 KEG11784.1 - 6.7e-05 23.0 3.9 0.00018 21.6 2.7 1.7 1 1 1 2 2 2 1 Presenilin enhancer-2 subunit of gamma secretase Ndc1_Nup PF09531.5 KEG11784.1 - 1.5 7.1 3.7 1.7 6.9 2.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Acid_PPase PF12689.2 KEG11786.1 - 4.3e-24 85.0 0.1 4.9e-24 84.8 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase DUF2608 PF11019.3 KEG11786.1 - 0.062 12.2 0.2 0.083 11.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) HAP1_N PF04849.8 KEG11787.1 - 0.084 11.8 33.4 0.067 12.1 15.4 2.3 1 1 1 2 2 2 0 HAP1 N-terminal conserved region Reo_sigmaC PF04582.7 KEG11787.1 - 0.17 11.0 7.3 2.2 7.3 1.4 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein GldM_N PF12081.3 KEG11787.1 - 0.21 11.0 5.7 0.45 10.0 0.0 3.3 2 1 1 3 3 3 0 GldM N-terminal domain DUF3394 PF11874.3 KEG11787.1 - 1.5 8.3 6.1 0.31 10.5 1.5 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3394) DUF948 PF06103.6 KEG11787.1 - 4 7.3 9.3 1.6 8.6 0.6 3.1 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Tet_JBP PF12851.2 KEG11787.1 - 4.8 6.4 6.8 5.7 6.2 2.5 2.6 1 1 1 2 2 2 0 Oxygenase domain of the 2OGFeDO superfamily Hpt PF01627.18 KEG11787.1 - 8.2 6.5 18.6 77 3.3 9.7 3.8 2 1 0 2 2 2 0 Hpt domain WD40 PF00400.27 KEG11788.1 - 1.2e-10 40.8 11.0 0.0045 16.8 0.1 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat Dynein_heavy PF03028.10 KEG11788.1 - 0.021 12.8 0.0 0.03 12.3 0.0 1.1 1 0 0 1 1 1 0 Dynein heavy chain and region D6 of dynein motor PDZ_2 PF13180.1 KEG11788.1 - 0.024 14.5 0.3 0.056 13.3 0.2 1.6 1 0 0 1 1 1 0 PDZ domain PQQ PF01011.16 KEG11788.1 - 0.091 12.3 0.0 0.77 9.4 0.0 2.5 2 0 0 2 2 2 0 PQQ enzyme repeat Tricorn_PDZ PF14685.1 KEG11788.1 - 0.11 12.2 0.1 0.27 11.0 0.1 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain PQQ_3 PF13570.1 KEG11788.1 - 0.59 10.4 3.9 7 7.0 0.0 3.8 4 0 0 4 4 4 0 PQQ-like domain Kinesin PF00225.18 KEG11789.1 - 2.4e-79 266.4 0.0 3.7e-79 265.8 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain ATG16 PF08614.6 KEG11789.1 - 0.13 12.0 14.9 0.024 14.4 1.8 2.9 2 1 0 3 3 3 0 Autophagy protein 16 (ATG16) Spc7 PF08317.6 KEG11789.1 - 0.26 9.9 5.1 4 6.0 0.1 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein FlxA PF14282.1 KEG11789.1 - 0.32 10.9 7.6 1.9 8.4 0.6 2.5 2 0 0 2 2 2 0 FlxA-like protein Kinesin PF00225.18 KEG11790.1 - 3.5e-79 265.9 0.0 3.5e-79 265.9 0.0 2.2 3 0 0 3 3 3 1 Kinesin motor domain DUF1192 PF06698.6 KEG11790.1 - 0.00084 19.1 0.9 0.00084 19.1 0.6 5.8 5 2 3 8 8 8 1 Protein of unknown function (DUF1192) TBPIP PF07106.8 KEG11790.1 - 0.45 10.0 66.6 0.027 14.0 8.8 5.1 1 1 6 7 7 7 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Reo_sigmaC PF04582.7 KEG11790.1 - 1.7 7.7 24.9 5.5 6.0 6.5 4.0 1 1 3 4 4 4 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 KEG11790.1 - 1.8 6.9 58.7 0.11 10.9 20.9 2.4 1 1 1 2 2 2 0 AAA domain DUF3584 PF12128.3 KEG11790.1 - 2.1 5.5 79.3 0.016 12.5 35.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Fib_alpha PF08702.5 KEG11790.1 - 3.1 7.9 55.1 0.46 10.6 6.4 4.4 1 1 2 4 4 4 0 Fibrinogen alpha/beta chain family IncA PF04156.9 KEG11790.1 - 3.2 7.3 88.4 15 5.1 15.7 4.5 1 1 1 2 2 1 0 IncA protein Tropomyosin_1 PF12718.2 KEG11790.1 - 4.1 7.2 91.7 0.028 14.2 22.3 4.3 1 1 3 4 4 4 0 Tropomyosin like Apolipoprotein PF01442.13 KEG11790.1 - 6.6 6.1 82.8 0.5 9.8 31.9 3.4 1 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Filament PF00038.16 KEG11790.1 - 7.9 5.8 81.3 3.1 7.1 30.7 2.6 1 1 1 2 2 2 0 Intermediate filament protein DUF4417 PF14386.1 KEG11792.1 - 0.058 12.7 0.0 0.088 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4417) UvdE PF03851.9 KEG11792.1 - 0.13 11.2 0.5 0.2 10.6 0.3 1.1 1 0 0 1 1 1 0 UV-endonuclease UvdE DUF4370 PF14290.1 KEG11793.1 - 0.012 15.1 0.0 0.026 14.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4370) Myosin_TH1 PF06017.8 KEG11797.1 - 7.4e-15 54.7 0.3 2.8e-06 26.7 0.0 3.4 2 1 1 3 3 3 3 Myosin tail RUN PF02759.14 KEG11797.1 - 0.00019 21.2 0.0 0.087 12.5 0.0 2.6 2 0 0 2 2 2 2 RUN domain PH PF00169.24 KEG11797.1 - 0.00083 19.5 0.0 0.0068 16.5 0.0 2.4 2 0 0 2 2 2 1 PH domain Thymidylate_kin PF02223.12 KEG11799.1 - 0.011 15.1 0.4 0.33 10.3 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase Host_attach PF10116.4 KEG11802.1 - 0.021 15.0 0.5 0.021 15.0 0.4 1.7 2 0 0 2 2 2 0 Protein required for attachment to host cells DUF1764 PF08576.5 KEG11803.1 - 0.32 11.7 6.8 1.3 9.8 3.0 3.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) SUV3_C PF12513.3 KEG11804.1 - 0.2 11.1 0.3 0.35 10.3 0.2 1.4 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal PC_rep PF01851.17 KEG11805.1 - 3.3e-20 71.0 16.2 0.00033 20.7 0.1 7.9 7 0 0 7 7 7 4 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KEG11805.1 - 9.1e-13 48.3 1.5 7e-08 32.6 0.0 5.0 2 1 3 5 5 5 3 HEAT repeats HEAT PF02985.17 KEG11805.1 - 0.0027 17.6 0.4 10 6.4 0.0 4.9 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 KEG11805.1 - 0.04 14.4 0.9 17 6.0 0.0 4.8 5 0 0 5 5 5 0 HEAT-like repeat Nol1_Nop2_Fmu PF01189.12 KEG11806.1 - 6.8e-06 25.6 0.2 1.6e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 NOL1/NOP2/sun family Ribosomal_60s PF00428.14 KEG11807.1 - 6.5e-05 23.2 7.9 0.006 16.9 1.9 3.2 3 0 0 3 3 3 2 60s Acidic ribosomal protein Pkinase PF00069.20 KEG11808.1 - 1.6e-16 60.2 0.0 2.6e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG11808.1 - 6.4e-05 22.1 0.0 0.00011 21.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.27 KEG11808.1 - 0.00029 20.5 4.9 0.0006 19.6 0.1 3.6 4 0 0 4 4 4 1 WD domain, G-beta repeat Seadorna_VP7 PF07387.6 KEG11808.1 - 0.2 10.4 0.0 0.34 9.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 ArfGap PF01412.13 KEG11809.1 - 2e-38 130.7 0.8 3.6e-38 129.9 0.6 1.4 1 1 0 1 1 1 1 Putative GTPase activating protein for Arf DUF21 PF01595.15 KEG11810.1 - 4.6e-33 114.0 0.7 8.8e-33 113.1 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 KEG11810.1 - 1.2e-08 34.6 0.3 0.00011 21.8 0.1 2.5 2 0 0 2 2 2 2 CBS domain cNMP_binding PF00027.24 KEG11810.1 - 0.03 14.1 0.0 0.064 13.0 0.0 1.5 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain DUF1035 PF06281.7 KEG11810.1 - 0.1 12.4 0.8 0.33 10.7 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1035) FliX PF10768.4 KEG11811.1 - 0.81 9.9 7.9 0.46 10.7 1.7 2.4 2 1 1 3 3 3 0 Class II flagellar assembly regulator Vps52 PF04129.7 KEG11812.1 - 8.2e-21 74.1 1.4 2e-19 69.5 1.0 2.7 1 1 0 1 1 1 1 Vps52 / Sac2 family MutS_III PF05192.13 KEG11812.1 - 0.00096 18.9 0.1 0.58 9.8 0.0 3.4 2 1 0 2 2 2 2 MutS domain III FAD_binding_1 PF00667.15 KEG11813.1 - 3e-43 147.8 0.0 4.8e-43 147.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KEG11813.1 - 7.4e-23 81.1 0.0 1.6e-22 80.0 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KEG11813.1 - 1.3e-16 61.1 0.0 2.8e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain WD40 PF00400.27 KEG11814.1 - 1.5e-29 100.7 0.4 6e-08 32.2 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KEG11814.1 - 0.0022 16.8 0.1 0.04 12.6 0.0 2.1 1 1 1 2 2 2 2 Nup133 N terminal like RRM_1 PF00076.17 KEG11816.1 - 1.2e-11 44.0 0.1 2.3e-11 43.1 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG11816.1 - 2.5e-10 40.1 0.0 5e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) eIF3g PF12353.3 KEG11816.1 - 1.5e-05 24.9 1.1 1.5e-05 24.9 0.8 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G RRM_5 PF13893.1 KEG11816.1 - 0.00016 21.4 0.0 0.00035 20.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.3 KEG11816.1 - 0.0074 15.5 0.1 0.025 13.9 0.0 1.9 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated NID PF07292.8 KEG11816.1 - 0.07 13.1 0.2 6.2 6.9 0.0 3.1 3 0 0 3 3 3 0 Nmi/IFP 35 domain (NID) MFS_1 PF07690.11 KEG11818.1 - 1.2e-24 86.7 29.9 8.2e-23 80.6 15.4 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.27 KEG11822.1 - 0.00019 21.2 8.2 0.05 13.5 0.0 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat EMP70 PF02990.11 KEG11824.1 - 3.3e-100 336.0 5.2 9e-99 331.2 3.6 2.0 1 1 0 1 1 1 1 Endomembrane protein 70 GP41 PF00517.12 KEG11824.1 - 0.56 9.7 2.7 34 3.8 0.0 2.5 2 0 0 2 2 2 0 Retroviral envelope protein Sin_N PF04801.8 KEG11825.1 - 7.9e-95 318.1 0.0 1.6e-94 317.1 0.0 1.5 2 0 0 2 2 2 1 Sin-like protein conserved region Dpy-30 PF05186.8 KEG11827.1 - 4.9e-16 57.9 0.1 8.5e-16 57.1 0.1 1.4 1 0 0 1 1 1 1 Dpy-30 motif AAA_28 PF13521.1 KEG11827.1 - 3.4e-06 27.0 1.0 0.00015 21.7 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 KEG11827.1 - 6.5e-05 23.7 0.0 0.00043 21.0 0.0 2.5 1 0 0 1 1 1 1 AAA domain RIIa PF02197.12 KEG11827.1 - 0.00029 20.1 0.0 0.00075 18.8 0.0 1.8 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit ADK PF00406.17 KEG11827.1 - 0.0019 18.0 0.0 0.23 11.3 0.0 3.5 3 0 0 3 3 3 1 Adenylate kinase 3Beta_HSD PF01073.14 KEG11827.1 - 0.007 15.0 0.0 0.02 13.6 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KEG11827.1 - 0.0071 15.7 0.0 0.051 13.0 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family AAA_18 PF13238.1 KEG11827.1 - 0.0089 16.3 4.2 0.043 14.1 0.0 4.1 4 1 0 4 4 4 1 AAA domain GP41 PF00517.12 KEG11828.1 - 9.3 5.7 7.7 25 4.3 0.1 2.5 2 0 0 2 2 2 0 Retroviral envelope protein ACBP PF00887.14 KEG11830.1 - 5.9e-17 61.1 0.0 1.1e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein S10_plectin PF03501.10 KEG11831.1 - 5.7e-34 115.8 0.0 6.6e-34 115.6 0.0 1.0 1 0 0 1 1 1 1 Plectin/S10 domain API5 PF05918.6 KEG11831.1 - 7.6 4.9 11.8 10 4.5 8.2 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Myosin_TH1 PF06017.8 KEG11832.1 - 0.0047 16.2 0.0 0.007 15.6 0.0 1.3 1 0 0 1 1 1 1 Myosin tail Sld5 PF05916.6 KEG11832.1 - 0.014 15.6 0.9 0.17 12.2 0.8 2.0 1 1 1 2 2 2 0 GINS complex protein Spc24 PF08286.6 KEG11832.1 - 0.072 12.7 2.2 0.13 12.0 1.5 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 INCENP_ARK-bind PF03941.10 KEG11833.1 - 0.11 12.3 0.0 4.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region Dynein_heavy PF03028.10 KEG11834.1 - 2.5e-223 743.1 6.3 3.3e-223 742.7 0.0 3.5 4 0 0 4 4 3 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 KEG11834.1 - 2.5e-129 431.3 14.2 2.5e-129 431.3 9.8 3.4 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 KEG11834.1 - 3.4e-92 308.1 0.0 8.7e-92 306.8 0.0 1.7 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 KEG11834.1 - 7.1e-69 231.7 0.1 1.4e-68 230.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 KEG11834.1 - 2.8e-58 196.4 0.2 7.5e-58 195.0 0.2 1.7 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 KEG11834.1 - 7.1e-43 146.6 6.9 1.2e-42 145.9 4.8 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.2 KEG11834.1 - 1.1e-38 132.9 0.0 2e-38 132.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 AAA_5 PF07728.9 KEG11834.1 - 6.7e-15 55.0 0.0 0.0007 19.3 0.0 6.6 5 2 0 5 5 5 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KEG11834.1 - 1.5e-09 38.0 0.0 0.00018 21.6 0.0 5.5 5 0 0 5 5 5 1 AAA domain RNA_helicase PF00910.17 KEG11834.1 - 6.2e-06 26.3 0.0 0.11 12.6 0.0 4.5 4 0 0 4 4 4 2 RNA helicase AAA PF00004.24 KEG11834.1 - 7.5e-06 26.1 0.0 0.47 10.6 0.0 3.9 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KEG11834.1 - 4e-05 23.3 0.3 0.0071 16.0 0.0 3.4 3 0 0 3 3 3 1 NACHT domain AAA_17 PF13207.1 KEG11834.1 - 0.00018 22.3 0.0 1.3 9.8 0.0 4.5 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 KEG11834.1 - 0.0017 18.0 0.3 0.66 9.7 0.1 4.0 4 0 0 4 4 4 1 Part of AAA domain AAA_25 PF13481.1 KEG11834.1 - 0.0041 16.5 0.8 1.6 8.1 0.0 3.5 3 0 0 3 3 3 1 AAA domain ATP-synt_ab PF00006.20 KEG11834.1 - 0.0086 15.5 0.0 0.51 9.7 0.0 2.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.1 KEG11834.1 - 0.0098 15.7 0.1 2.4 8.0 0.0 4.1 4 0 0 4 4 3 1 AAA domain AAA_18 PF13238.1 KEG11834.1 - 0.01 16.1 0.5 8 6.7 0.0 5.0 5 0 0 5 5 4 0 AAA domain AAA_16 PF13191.1 KEG11834.1 - 0.032 14.2 12.7 0.69 9.8 0.0 5.2 5 2 0 5 5 3 0 AAA ATPase domain Ribosomal_S13 PF00416.17 KEG11835.1 - 8.4e-33 113.0 1.4 3.8e-31 107.7 1.0 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 Tox-URI2 PF15653.1 KEG11835.1 - 0.029 14.5 0.6 8 6.7 0.1 2.4 2 0 0 2 2 2 0 URI fold toxin 2 PGM_PMM_II PF02879.11 KEG11835.1 - 0.055 13.7 0.0 0.82 10.0 0.0 2.2 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DUF4004 PF13171.1 KEG11835.1 - 0.072 13.2 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4004) FbpA PF05833.6 KEG11835.1 - 0.1 11.1 0.0 0.18 10.3 0.0 1.6 1 1 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) PP28 PF10252.4 KEG11835.1 - 8.4 6.4 7.3 39 4.3 5.0 2.0 1 1 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 Ribonuclease_3 PF00636.21 KEG11837.1 - 0.0059 17.0 0.0 0.047 14.1 0.0 2.4 2 1 0 2 2 2 1 Ribonuclease III domain Metallophos PF00149.23 KEG11838.1 - 1.9e-25 89.4 0.2 2.4e-25 89.1 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4407 PF14362.1 KEG11839.1 - 0.04 12.8 0.1 0.048 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlxA PF14282.1 KEG11839.1 - 0.094 12.6 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 FlxA-like protein DUF1311 PF07007.7 KEG11839.1 - 0.2 11.7 4.6 0.34 11.0 3.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1311) DUF1515 PF07439.6 KEG11839.1 - 0.34 10.7 1.7 0.57 10.0 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) NAD_binding_10 PF13460.1 KEG11840.1 - 9.1e-11 42.0 0.3 1.7e-05 24.9 0.0 2.3 2 0 0 2 2 2 2 NADH(P)-binding 3Beta_HSD PF01073.14 KEG11840.1 - 8.3e-06 24.7 0.1 4.6e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KEG11840.1 - 0.00037 19.9 0.0 0.022 14.1 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KEG11840.1 - 0.0023 17.2 0.5 0.01 15.1 0.4 1.9 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 KEG11840.1 - 0.0039 16.1 0.0 0.0073 15.2 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein F420_oxidored PF03807.12 KEG11840.1 - 0.011 16.1 0.0 0.6 10.5 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 KEG11840.1 - 0.063 13.2 0.3 8.4 6.4 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain adh_short PF00106.20 KEG11840.1 - 0.31 10.9 4.8 49 3.7 3.3 3.0 2 1 0 2 2 2 0 short chain dehydrogenase Rz1 PF06085.6 KEG11841.1 - 0.016 14.6 0.1 0.04 13.3 0.1 1.6 1 0 0 1 1 1 0 Lipoprotein Rz1 precursor CBF PF03914.12 KEG11842.1 - 1.3e-37 128.7 0.4 2.7e-37 127.7 0.0 1.7 2 0 0 2 2 2 1 CBF/Mak21 family DUF3721 PF12518.3 KEG11842.1 - 3 7.5 5.2 0.35 10.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function SpoIIE PF07228.7 KEG11843.1 - 3.8e-09 36.5 0.1 5.2e-09 36.0 0.1 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 KEG11843.1 - 1.5e-06 27.7 0.0 2.1e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C Tcp10_C PF07202.8 KEG11844.1 - 0.00094 18.7 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 T-complex protein 10 C-terminus UL40 PF10682.4 KEG11844.1 - 0.021 14.3 0.1 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein of human cytomegalovirus HHV-5 Sod_Fe_C PF02777.13 KEG11845.1 - 0.066 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, C-terminal domain Dynein_light PF01221.13 KEG11845.1 - 0.081 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Dynein light chain type 1 SIP1 PF04938.7 KEG11846.1 - 0.00068 19.0 0.8 0.0016 17.8 0.6 1.5 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Transmemb_17 PF09799.4 KEG11847.1 - 5.6e-27 94.2 10.7 7.3e-27 93.8 7.4 1.1 1 0 0 1 1 1 1 Predicted membrane protein Cytochrom_B558a PF05038.8 KEG11847.1 - 0.0021 17.7 1.6 0.0027 17.3 1.1 1.3 1 0 0 1 1 1 1 Cytochrome Cytochrome b558 alpha-subunit MFS_1 PF07690.11 KEG11847.1 - 0.049 12.3 10.2 0.075 11.7 7.0 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF872 PF05915.7 KEG11847.1 - 0.26 11.1 2.6 0.26 11.1 1.0 1.6 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) Yip1 PF04893.12 KEG11847.1 - 1.4 8.4 17.1 4.2 6.8 11.9 1.7 1 1 0 1 1 1 0 Yip1 domain CoA_binding_3 PF13727.1 KEG11847.1 - 4.5 7.0 9.6 1.9 8.3 0.7 2.1 2 0 0 2 2 2 0 CoA-binding domain DUF2039 PF10217.4 KEG11848.1 - 6.3e-27 93.4 17.1 1.2e-26 92.4 11.8 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) DUF3584 PF12128.3 KEG11850.1 - 0.00012 19.6 67.4 0.00012 19.6 46.7 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF3584) FliJ PF02050.11 KEG11850.1 - 0.00028 20.9 19.0 0.00028 20.9 13.2 8.6 5 2 3 9 9 9 1 Flagellar FliJ protein Rootletin PF15035.1 KEG11850.1 - 0.0056 16.6 18.0 0.0056 16.6 12.5 9.3 4 2 4 8 8 8 1 Ciliary rootlet component, centrosome cohesion Fe_dep_repress PF01325.14 KEG11850.1 - 0.31 10.9 13.7 27 4.7 0.6 5.3 2 2 3 6 6 6 0 Iron dependent repressor, N-terminal DNA binding domain CRISPR_Cas2 PF09827.4 KEG11850.1 - 1.5 8.9 6.8 1.7 8.8 0.3 4.4 3 0 0 3 3 3 0 CRISPR associated protein Cas2 Cast PF10174.4 KEG11850.1 - 2.8 5.8 147.2 20 3.0 9.0 4.4 1 1 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone PSP1 PF04468.7 KEG11851.1 - 3.6e-25 87.7 1.0 3.6e-25 87.7 0.7 1.9 2 0 0 2 2 2 1 PSP1 C-terminal conserved region Peptidase_M24 PF00557.19 KEG11852.1 - 2.5e-19 69.6 0.2 5.1e-19 68.6 0.1 1.5 1 1 0 1 1 1 1 Metallopeptidase family M24 MSP1_C PF07462.6 KEG11852.1 - 0.26 9.6 2.5 0.41 8.9 1.7 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus LZ_Tnp_IS66 PF13007.2 KEG11853.1 - 0.33 11.6 10.9 0.49 11.0 7.6 1.3 1 1 0 1 1 1 0 Transposase C of IS166 homeodomain Nop53 PF07767.6 KEG11853.1 - 0.85 8.5 20.4 0.96 8.3 14.2 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) NOA36 PF06524.7 KEG11853.1 - 1.5 8.0 10.3 1.5 8.0 7.1 1.2 1 0 0 1 1 1 0 NOA36 protein Vfa1 PF08432.5 KEG11853.1 - 3.1 7.8 11.0 3.2 7.7 7.6 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TRAP_alpha PF03896.11 KEG11853.1 - 6 5.7 8.2 6.4 5.6 5.7 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4407 PF14362.1 KEG11853.1 - 6 5.7 6.3 7.1 5.4 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CDC45 PF02724.9 KEG11853.1 - 6.3 4.6 26.5 6.5 4.6 18.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Lectin_leg-like PF03388.8 KEG11854.1 - 1.2e-46 158.7 0.5 1.7e-46 158.1 0.0 1.5 2 0 0 2 2 2 1 Legume-like lectin family U-box PF04564.10 KEG11855.1 - 1e-07 31.7 0.0 2.6e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.3 KEG11855.1 - 0.0099 15.3 0.0 0.023 14.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 KEG11855.1 - 0.13 11.9 0.0 1.6 8.4 0.0 2.8 3 0 0 3 3 3 0 RING-type zinc-finger zf-DHHC PF01529.15 KEG11856.1 - 3e-33 114.6 1.4 3e-33 114.6 1.0 1.9 1 1 0 1 1 1 1 DHHC palmitoyltransferase LRV_FeS PF05484.6 KEG11856.1 - 0.043 13.4 5.0 0.091 12.3 3.5 1.5 1 0 0 1 1 1 0 LRV protein FeS4 cluster HemY_N PF07219.8 KEG11856.1 - 0.45 10.0 5.9 2 7.9 0.1 3.1 3 0 0 3 3 3 0 HemY protein N-terminus TGF_beta_GS PF08515.7 KEG11856.1 - 1.2 8.4 4.9 2.1 7.7 0.7 2.4 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif Cse1 PF08506.5 KEG11857.1 - 0.0033 16.0 0.7 0.0096 14.5 0.0 2.2 3 0 0 3 3 3 1 Cse1 SDA1 PF05285.7 KEG11857.1 - 0.07 12.4 18.4 0.13 11.5 12.8 1.3 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 KEG11857.1 - 0.38 8.7 13.4 0.63 8.0 9.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 KEG11857.1 - 1.2 7.5 16.6 2 6.8 11.5 1.2 1 0 0 1 1 1 0 Daxx Family DUF1510 PF07423.6 KEG11857.1 - 1.4 8.2 9.1 9.4 5.5 5.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF948 PF06103.6 KEG11858.1 - 0.012 15.4 2.1 2.2 8.2 0.3 3.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) SnoaL_2 PF12680.2 KEG11858.1 - 0.043 14.2 2.2 1.9 8.9 0.0 3.7 3 1 1 4 4 4 0 SnoaL-like domain DUF1188 PF06690.6 KEG11858.1 - 0.16 11.0 0.2 0.28 10.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) DUF2570 PF10828.3 KEG11858.1 - 0.79 9.3 7.2 0.63 9.6 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) TFIIA PF03153.8 KEG11858.1 - 2.3 8.0 11.1 4.1 7.2 0.9 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Fib_alpha PF08702.5 KEG11858.1 - 3.8 7.6 8.4 0.21 11.7 0.3 3.0 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family Amidinotransf PF02274.12 KEG11859.1 - 0.024 13.7 0.0 0.5 9.4 0.0 2.1 2 0 0 2 2 2 0 Amidinotransferase COX17 PF05051.8 KEG11861.1 - 3.4e-20 71.7 21.7 6.9e-19 67.6 5.4 2.1 2 0 0 2 2 2 2 Cytochrome C oxidase copper chaperone (COX17) C1_2 PF03107.11 KEG11861.1 - 0.62 10.2 0.1 0.62 10.2 0.1 3.1 3 0 0 3 3 3 0 C1 domain BMC PF00936.14 KEG11862.1 - 0.085 12.5 0.9 2.3 7.9 0.0 2.7 2 1 0 2 2 2 0 BMC domain SUZ PF12752.2 KEG11862.1 - 0.093 13.2 1.6 0.62 10.6 1.7 1.9 2 0 0 2 2 2 0 SUZ domain tRNA_edit PF04073.10 KEG11864.1 - 3.9e-23 81.6 0.0 4.8e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain NosD PF05048.8 KEG11865.1 - 0.46 9.5 6.6 9.2 5.3 0.1 3.6 4 0 0 4 4 4 0 Periplasmic copper-binding protein (NosD) PGAP1 PF07819.8 KEG11866.1 - 8.3e-35 120.4 0.3 1.2e-34 119.8 0.2 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KEG11866.1 - 3.8e-07 29.9 0.1 9.7e-07 28.6 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEG11866.1 - 1.1e-06 28.6 0.0 1.1e-06 28.6 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 KEG11866.1 - 0.0014 18.2 0.0 0.0028 17.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.15 KEG11866.1 - 0.0038 16.8 0.1 0.0064 16.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 KEG11866.1 - 0.08 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain DUF3357 PF11837.3 KEG11866.1 - 0.2 11.5 1.7 1 9.2 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) DUF915 PF06028.6 KEG11866.1 - 0.31 10.0 0.0 0.54 9.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DEAD PF00270.24 KEG11867.1 - 8.3e-19 67.6 0.0 2.6e-18 66.0 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEG11867.1 - 2.7e-06 27.1 0.2 9.6e-06 25.3 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEG11867.1 - 3.5e-05 23.7 0.0 0.00048 19.9 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit ATP_synt_H PF05493.8 KEG11868.1 - 1.5e-22 79.4 2.9 1.6e-22 79.2 2.0 1.0 1 0 0 1 1 1 1 ATP synthase subunit H Claudin_2 PF13903.1 KEG11868.1 - 0.078 12.6 2.8 0.079 12.6 2.0 1.0 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF4131 PF13567.1 KEG11868.1 - 0.94 8.8 3.8 1.1 8.6 2.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) WD40 PF00400.27 KEG11869.1 - 4.1e-32 108.8 12.2 2e-07 30.6 0.1 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 KEG11869.1 - 0.092 12.5 0.0 5.3 6.8 0.0 2.9 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region DUF1937 PF09152.5 KEG11870.1 - 0.043 14.3 0.4 0.45 11.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1937) VMA21 PF09446.5 KEG11870.1 - 0.39 10.6 3.6 0.82 9.6 2.5 1.5 1 0 0 1 1 1 0 VMA21-like domain DUF1469 PF07332.6 KEG11870.1 - 3.4 7.4 5.2 5.9 6.6 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) RHH_1 PF01402.16 KEG11871.1 - 0.00097 18.9 0.0 0.003 17.3 0.0 1.9 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family Ank_2 PF12796.2 KEG11872.1 - 2.9e-15 56.3 0.5 9e-07 29.1 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEG11872.1 - 1.1e-14 54.4 4.7 1.3e-05 25.5 0.0 3.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEG11872.1 - 1.4e-14 53.7 0.3 3.7e-07 30.1 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KEG11872.1 - 6.2e-14 51.0 0.5 1.1e-05 24.9 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 KEG11872.1 - 5.9e-12 44.6 0.1 0.00013 21.8 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat DUF2803 PF10972.3 KEG11872.1 - 0.02 14.4 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2803) Rubella_Capsid PF05750.6 KEG11872.1 - 0.084 12.2 1.1 0.12 11.7 0.7 1.2 1 0 0 1 1 1 0 Rubella capsid protein Metallophos PF00149.23 KEG11873.1 - 8.1e-43 146.1 0.2 9.9e-43 145.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase BTB_2 PF02214.17 KEG11874.1 - 1.8e-11 44.0 0.0 3.2e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF4539 PF15072.1 KEG11875.1 - 5.3e-23 80.5 0.8 8e-23 79.9 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) CTC1 PF15489.1 KEG11875.1 - 0.057 10.7 1.2 0.067 10.5 0.8 1.1 1 0 0 1 1 1 0 CST, telomere maintenance, complex subunit CTC1 SNARE_assoc PF09335.6 KEG11876.1 - 3.4e-09 36.9 1.5 3.4e-09 36.9 1.0 2.7 3 0 0 3 3 3 1 SNARE associated Golgi protein EF-hand_7 PF13499.1 KEG11876.1 - 0.0029 17.7 0.1 0.013 15.6 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 KEG11876.1 - 0.0032 16.7 0.0 0.0073 15.6 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.27 KEG11876.1 - 0.0036 16.5 0.0 0.0076 15.4 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 KEG11876.1 - 0.012 15.4 0.0 0.034 14.0 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain Sas10 PF09368.5 KEG11877.1 - 4.8e-20 71.5 4.6 4.8e-20 71.5 3.2 2.4 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 KEG11877.1 - 5.1e-19 68.2 1.1 1.9e-18 66.4 0.8 2.0 1 0 0 1 1 1 1 Sas10/Utp3/C1D family YqcI_YcgG PF08892.6 KEG11878.1 - 0.046 13.2 1.2 0.056 13.0 0.2 1.5 2 0 0 2 2 2 0 YqcI/YcgG family V_ATPase_I PF01496.14 KEG11881.1 - 0.057 11.2 1.0 0.063 11.1 0.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AMP-binding_C_2 PF14535.1 KEG11881.1 - 0.071 13.1 0.2 0.1 12.6 0.2 1.2 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain FliD_N PF02465.13 KEG11881.1 - 0.14 12.5 1.0 0.28 11.5 0.7 1.5 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus SNF2_N PF00176.18 KEG11882.1 - 2.7e-61 206.9 0.4 4.5e-61 206.2 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEG11882.1 - 3.7e-11 42.7 0.0 1.1e-10 41.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 KEG11882.1 - 1.2e-07 31.6 3.6 4.5e-07 29.7 2.6 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 KEG11882.1 - 4.7e-07 29.4 0.0 8.1e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.20 KEG11882.1 - 7.5e-07 28.7 4.6 2.2e-06 27.2 3.2 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEG11882.1 - 3.8e-06 26.4 5.0 7.5e-06 25.5 3.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEG11882.1 - 5.9e-06 25.8 5.5 1.4e-05 24.7 3.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KEG11882.1 - 7.8e-05 22.4 5.8 0.00027 20.6 4.0 2.0 1 0 0 1 1 1 1 Ring finger domain ResIII PF04851.10 KEG11882.1 - 0.00016 21.5 0.1 0.0011 18.8 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-4CXXC_R1 PF10497.4 KEG11882.1 - 0.0046 17.0 4.3 0.0046 17.0 3.0 2.0 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-C3HC4_4 PF15227.1 KEG11882.1 - 0.0078 16.0 5.7 0.012 15.4 3.4 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KEG11882.1 - 0.2 11.4 4.8 0.19 11.4 1.9 2.2 1 1 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.1 KEG11882.1 - 8.9 5.9 9.4 71 3.0 6.5 2.3 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 PGK PF00162.14 KEG11884.1 - 9.5e-108 360.1 0.0 1.3e-107 359.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoglycerate kinase cNMP_binding PF00027.24 KEG11884.1 - 4.6e-06 26.3 0.0 1.5e-05 24.6 0.0 2.0 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain LRR_4 PF12799.2 KEG11885.1 - 0.0002 20.9 6.2 0.00065 19.2 0.3 3.0 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG11885.1 - 0.0092 15.7 3.6 0.02 14.6 1.7 2.3 2 1 0 2 2 2 1 Leucine rich repeat zf-CCCH_2 PF14608.1 KEG11885.1 - 0.43 10.6 3.8 0.87 9.6 2.7 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type B3_4 PF03483.12 KEG11886.1 - 4e-18 65.4 0.0 6.7e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 KEG11886.1 - 1.6e-16 59.8 0.0 3.2e-15 55.7 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetase B5 domain DnaB_bind PF10410.4 KEG11886.1 - 0.079 12.9 0.0 18 5.3 0.0 2.5 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase Cir_N PF10197.4 KEG11887.1 - 0.017 15.1 1.0 0.017 15.1 0.7 3.8 4 1 1 5 5 5 0 N-terminal domain of CBF1 interacting co-repressor CIR YliH PF10799.3 KEG11887.1 - 0.19 11.3 1.6 0.2 11.3 0.0 1.9 2 0 0 2 2 2 0 Biofilm formation protein (YliH/bssR) TMA7 PF09072.5 KEG11887.1 - 1.7 9.1 9.5 1.2 9.6 2.6 2.8 2 0 0 2 2 2 0 Translation machinery associated TMA7 LRR_4 PF12799.2 KEG11888.1 - 1.2e-05 24.7 0.6 0.29 10.7 0.7 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 KEG11888.1 - 0.00025 20.6 0.1 0.00043 19.8 0.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeat RasGEF PF00617.14 KEG11889.1 - 1.3e-21 77.1 0.0 2.2e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KEG11889.1 - 4.4e-05 23.5 0.5 9.3e-05 22.4 0.3 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif ThiF PF00899.16 KEG11890.1 - 2.5e-42 143.9 0.2 4.6e-42 143.0 0.2 1.4 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 KEG11890.1 - 2.7e-26 90.9 0.4 5.6e-26 89.9 0.2 1.6 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 KEG11890.1 - 4.3e-06 27.0 0.0 1.2e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 KEG11890.1 - 0.03 14.4 0.2 0.082 13.0 0.1 1.8 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 KEG11890.1 - 0.031 13.2 0.2 0.047 12.6 0.2 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Ldh_1_N PF00056.18 KEG11890.1 - 0.049 13.4 0.6 0.11 12.2 0.2 1.8 1 1 1 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Strumpellin PF10266.4 KEG11891.1 - 0 1547.8 2.4 0 1547.7 1.6 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin NPV_P10 PF05531.7 KEG11891.1 - 0.063 13.5 0.3 1.8 8.8 0.0 3.3 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein COG5 PF10392.4 KEG11891.1 - 1.2 9.0 5.1 13 5.7 0.2 3.7 4 0 0 4 4 4 0 Golgi transport complex subunit 5 DUF2730 PF10805.3 KEG11893.1 - 8.3 6.2 7.9 0.53 10.0 0.9 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) DUF3482 PF11981.3 KEG11894.1 - 0.018 14.3 3.0 0.021 14.0 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) ISG65-75 PF11727.3 KEG11894.1 - 0.019 14.0 0.9 0.022 13.8 0.6 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein GAS PF13851.1 KEG11894.1 - 0.11 11.6 5.7 0.13 11.4 4.0 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding T5orf172 PF10544.4 KEG11894.1 - 0.14 12.5 1.4 0.16 12.3 1.0 1.2 1 0 0 1 1 1 0 T5orf172 domain GBP_C PF02841.9 KEG11894.1 - 0.32 10.1 5.1 0.3 10.2 3.5 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain V_ATPase_I PF01496.14 KEG11894.1 - 0.37 8.5 4.2 0.4 8.4 2.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TPR_MLP1_2 PF07926.7 KEG11894.1 - 0.42 10.3 8.0 0.45 10.2 4.9 1.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 KEG11894.1 - 1.2 8.6 8.6 1.3 8.5 6.0 1.1 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 KEG11894.1 - 3.1 6.7 6.4 3.2 6.6 4.5 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 M PF02370.11 KEG11894.1 - 9.9 6.9 8.5 4.3 8.0 0.8 2.8 2 0 0 2 2 2 0 M protein repeat MMR_HSR1 PF01926.18 KEG11895.1 - 7.2e-15 54.9 0.0 1.8e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KEG11895.1 - 5.8e-09 35.9 0.0 2.2e-06 27.6 0.0 2.7 2 0 0 2 2 2 2 Dynamin family Miro PF08477.8 KEG11895.1 - 1.1e-05 25.8 0.0 0.00021 21.7 0.0 2.7 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KEG11895.1 - 2.7e-05 23.6 0.0 0.00055 19.4 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 KEG11895.1 - 0.00095 18.3 0.0 0.0031 16.6 0.0 1.9 1 1 0 1 1 1 1 AIG1 family DUF258 PF03193.11 KEG11895.1 - 0.0035 16.5 0.1 0.0089 15.2 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 KEG11895.1 - 0.0052 15.8 0.0 0.01 14.8 0.0 1.5 1 0 0 1 1 1 1 Septin ABC_tran PF00005.22 KEG11895.1 - 0.052 13.8 0.0 0.28 11.4 0.0 2.2 1 0 0 1 1 1 0 ABC transporter Gtr1_RagA PF04670.7 KEG11895.1 - 0.08 12.0 0.0 0.31 10.1 0.0 1.9 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KEG11897.1 - 0.15 12.0 0.0 1.2 9.0 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase YbaB_DNA_bd PF02575.11 KEG11900.1 - 0.00012 21.8 0.0 0.00021 21.1 0.0 1.3 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family Myc_N PF01056.13 KEG11902.1 - 0.00058 19.1 6.4 0.0012 18.1 4.4 1.5 1 0 0 1 1 1 1 Myc amino-terminal region Nucleoplasmin PF03066.10 KEG11902.1 - 0.097 12.1 9.0 0.16 11.5 6.3 1.4 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 KEG11902.1 - 0.34 8.7 9.8 0.43 8.4 6.8 1.1 1 0 0 1 1 1 0 Nop14-like family Ribosomal_L39 PF00832.15 KEG11902.1 - 1.6 8.2 5.4 0.28 10.6 0.4 2.1 2 0 0 2 2 2 0 Ribosomal L39 protein Ribosomal_60s PF00428.14 KEG11902.1 - 2 8.8 16.4 2.4 8.6 10.0 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Peptidase_M8 PF01457.11 KEG11903.1 - 2.8e-140 468.1 1.8 4.3e-89 299.2 0.0 2.0 1 1 1 2 2 2 2 Leishmanolysin MIG-14_Wnt-bd PF06664.7 KEG11908.1 - 9.9 4.8 0.2 16 4.1 0.1 1.2 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion NAD_Gly3P_dh_C PF07479.9 KEG11909.1 - 5.8e-46 155.8 1.9 8.9e-46 155.3 1.3 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 KEG11909.1 - 1.9e-45 154.4 0.1 3.2e-45 153.6 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 KEG11909.1 - 5.1e-05 23.1 0.2 0.0021 17.8 0.0 2.4 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KEG11909.1 - 0.00016 22.0 0.3 0.0011 19.3 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent DUF1495 PF07381.6 KEG11909.1 - 0.0039 16.8 0.0 0.011 15.3 0.0 1.7 1 0 0 1 1 1 1 Winged helix DNA-binding domain (DUF1495) ApbA PF02558.11 KEG11909.1 - 0.0073 15.7 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 KEG11909.1 - 0.018 14.3 0.0 0.046 13.0 0.0 1.7 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DegS PF05384.6 KEG11909.1 - 0.025 13.8 0.1 0.047 12.9 0.0 1.4 1 0 0 1 1 1 0 Sensor protein DegS 3HCDH_N PF02737.13 KEG11909.1 - 0.062 12.9 1.1 0.18 11.4 0.1 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 KEG11909.1 - 0.19 12.1 1.0 2.3 8.6 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_60s PF00428.14 KEG11911.1 - 0.45 10.9 7.6 0.55 10.6 4.0 2.2 2 1 0 2 2 2 0 60s Acidic ribosomal protein UCH PF00443.24 KEG11912.1 - 3.8e-48 163.9 0.0 5.7e-48 163.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEG11912.1 - 1.2e-21 77.3 0.0 1.9e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Piwi PF02171.12 KEG11913.1 - 4.6e-12 45.5 0.0 7.6e-12 44.7 0.0 1.3 1 0 0 1 1 1 1 Piwi domain Pyr_redox_2 PF07992.9 KEG11914.1 - 8.2e-07 29.0 0.0 2.2e-05 24.4 0.0 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEG11914.1 - 1.2e-06 28.4 0.0 5.8e-06 26.2 0.0 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KEG11914.1 - 9.5e-06 25.8 0.0 0.032 14.3 0.0 2.8 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEG11914.1 - 8.5e-05 22.8 0.0 0.17 12.2 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEG11914.1 - 0.00035 20.3 0.0 0.0013 18.5 0.0 1.9 1 1 1 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 KEG11914.1 - 0.0021 17.0 0.1 0.0053 15.7 0.0 1.6 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KEG11914.1 - 0.0039 16.1 0.1 0.034 13.0 0.0 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KEG11914.1 - 0.0057 15.6 0.0 0.061 12.2 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 KEG11914.1 - 0.0078 15.3 0.0 0.068 12.2 0.0 2.3 2 0 0 2 2 2 1 Thi4 family NTF2 PF02136.15 KEG11915.1 - 2.1e-09 37.7 0.1 3.9e-09 36.8 0.1 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF501 PF04417.7 KEG11915.1 - 0.0079 16.0 1.8 0.0079 16.0 1.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF501) IncA PF04156.9 KEG11915.1 - 0.21 11.1 8.7 0.019 14.5 2.6 1.8 2 0 0 2 2 2 0 IncA protein V_ATPase_I PF01496.14 KEG11915.1 - 1.1 7.0 5.5 1.5 6.5 3.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Utp14 PF04615.8 KEG11915.1 - 1.9 6.5 47.7 2.5 6.1 33.1 1.0 1 0 0 1 1 1 0 Utp14 protein Kua-UEV1_localn PF10520.4 KEG11916.1 - 1.6e-66 223.3 3.5 2.1e-66 222.9 2.4 1.1 1 0 0 1 1 1 1 Kua-ubiquitin conjugating enzyme hybrid localisation domain Keratin_assoc PF09775.4 KEG11916.1 - 0.13 11.7 0.4 1.9 8.0 0.0 2.2 2 0 0 2 2 2 0 Keratinocyte-associated protein 2 ubiquitin PF00240.18 KEG11917.1 - 0.00074 18.8 0.0 0.0015 17.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family zf-B_box PF00643.19 KEG11917.1 - 0.0063 16.3 5.8 0.0063 16.3 4.0 6.7 5 2 1 6 6 6 2 B-box zinc finger Vps35 PF03635.12 KEG11920.1 - 6.9e-251 834.6 0.0 8e-251 834.4 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 F-box PF00646.28 KEG11922.1 - 0.066 12.8 0.0 2.8 7.6 0.0 2.4 1 1 1 2 2 2 0 F-box domain Arf PF00025.16 KEG11923.1 - 2.2e-68 228.9 0.1 2.4e-68 228.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KEG11923.1 - 4.7e-12 45.5 0.0 5.7e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 KEG11923.1 - 1e-10 41.2 0.0 1.2e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KEG11923.1 - 7.2e-10 38.0 0.6 2e-07 30.0 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KEG11923.1 - 5.9e-09 35.4 0.0 7.5e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KEG11923.1 - 2.2e-07 31.3 0.0 3.2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KEG11923.1 - 5.6e-06 26.2 0.0 7.1e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KEG11923.1 - 0.0033 16.8 0.2 0.015 14.6 0.2 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KEG11923.1 - 0.054 12.7 0.8 0.36 10.1 0.6 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B DRIM PF07539.7 KEG11923.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Down-regulated in metastasis Pkinase PF00069.20 KEG11924.1 - 1.8e-73 246.8 0.0 2.3e-73 246.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG11924.1 - 1.3e-41 142.4 0.0 1.6e-41 142.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG11924.1 - 1.1e-07 31.0 0.0 1.6e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like LRR_4 PF12799.2 KEG11924.1 - 9.3e-05 21.9 1.6 0.00032 20.2 0.4 2.2 1 1 1 2 2 2 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KEG11924.1 - 0.0002 21.0 0.8 1.6 9.0 0.1 3.6 3 0 0 3 3 3 2 Leucine Rich repeat APH PF01636.18 KEG11924.1 - 0.013 15.2 0.1 2 8.0 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family LRR_1 PF00560.28 KEG11924.1 - 0.018 14.9 1.3 9.2 6.7 0.1 3.1 2 0 0 2 2 2 0 Leucine Rich Repeat Kdo PF06293.9 KEG11924.1 - 0.019 14.0 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KEG11924.1 - 0.057 12.7 0.0 0.09 12.1 0.0 1.2 1 0 0 1 1 1 0 RIO1 family GCR1_C PF12550.3 KEG11925.1 - 0.022 14.6 0.0 0.069 13.0 0.0 1.9 2 0 0 2 2 2 0 Transcriptional activator of glycolytic enzymes RRM_1 PF00076.17 KEG11925.1 - 0.13 11.9 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DnaJ PF00226.26 KEG11926.1 - 1.5e-08 34.2 0.0 2.6e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain zf-RING_2 PF13639.1 KEG11927.1 - 1.4e-11 43.9 5.6 1.4e-11 43.9 3.9 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KEG11927.1 - 6.1e-10 38.9 5.0 1.6e-09 37.6 3.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KEG11927.1 - 1.6e-08 34.5 1.5 1.6e-08 34.5 1.1 2.0 2 1 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KEG11927.1 - 3e-08 33.2 3.1 6.6e-08 32.1 2.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEG11927.1 - 8.8e-08 31.6 3.3 2e-07 30.5 2.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KEG11927.1 - 3.6e-07 29.7 1.6 1e-06 28.3 0.3 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 KEG11927.1 - 4.3e-07 29.5 2.8 4.3e-07 29.5 1.9 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KEG11927.1 - 2.2e-06 27.4 2.2 9.5e-06 25.3 1.6 2.1 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 KEG11927.1 - 0.00079 19.2 1.0 0.00079 19.2 0.7 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.1 KEG11927.1 - 0.0044 16.7 1.0 0.2 11.3 0.1 2.6 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 Prok-RING_4 PF14447.1 KEG11927.1 - 0.0066 15.9 2.2 0.31 10.6 0.0 2.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 CpXC PF14353.1 KEG11927.1 - 0.015 15.2 0.4 0.031 14.2 0.3 1.4 1 1 0 1 1 1 0 CpXC protein Rtf2 PF04641.7 KEG11927.1 - 0.017 14.3 0.1 0.025 13.7 0.1 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger FANCL_C PF11793.3 KEG11927.1 - 0.033 14.1 5.7 0.9 9.5 4.1 2.6 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_4 PF14570.1 KEG11927.1 - 0.039 13.5 1.5 0.1 12.1 1.1 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 KEG11927.1 - 0.094 12.7 2.9 0.32 11.0 2.0 2.0 1 1 0 1 1 1 0 RING-variant domain zf-Nse PF11789.3 KEG11927.1 - 0.12 11.9 3.5 0.089 12.3 0.6 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-P11 PF03854.9 KEG11927.1 - 0.39 10.2 4.9 1.9 7.9 3.4 2.1 1 1 1 2 2 2 0 P-11 zinc finger zf-MIZ PF02891.15 KEG11927.1 - 4.5 6.8 7.2 33 4.0 5.0 2.4 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger FdhD-NarQ PF02634.10 KEG11928.1 - 0.043 13.2 1.9 0.087 12.2 1.3 1.4 1 0 0 1 1 1 0 FdhD/NarQ family DUF4123 PF13503.1 KEG11928.1 - 0.18 11.7 3.0 0.25 11.3 1.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4123) Suf PF05843.9 KEG11928.1 - 0.36 10.5 4.6 0.58 9.8 3.2 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Prok-RING_4 PF14447.1 KEG11928.1 - 0.46 10.0 4.6 1.4 8.5 3.2 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PAT1 PF09770.4 KEG11928.1 - 1.3 7.1 11.1 1.9 6.6 7.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3522 PF12036.3 KEG11930.1 - 7.6e-28 97.5 3.1 8.7e-28 97.3 2.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) TctB PF07331.6 KEG11930.1 - 0.0014 18.2 1.3 0.0019 17.8 0.4 1.7 2 1 0 2 2 2 1 Tripartite tricarboxylate transporter TctB family HlyIII PF03006.15 KEG11930.1 - 0.0094 15.3 5.5 0.018 14.4 3.8 1.4 1 1 0 1 1 1 1 Haemolysin-III related DUF1538 PF07556.6 KEG11930.1 - 0.051 12.6 1.6 0.084 11.9 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1538) DUF3488 PF11992.3 KEG11930.1 - 0.08 11.5 0.7 0.1 11.2 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) Ceramidase PF05875.7 KEG11930.1 - 0.11 11.6 7.9 2.7 7.0 5.5 2.1 1 1 0 1 1 1 0 Ceramidase MFS_1 PF07690.11 KEG11930.1 - 0.11 11.1 3.9 0.14 10.8 2.7 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF3040 PF11239.3 KEG11930.1 - 0.14 12.2 0.1 0.35 10.9 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) 7TMR-DISM_7TM PF07695.6 KEG11930.1 - 0.29 10.7 6.4 0.89 9.1 4.5 1.7 1 1 0 1 1 1 0 7TM diverse intracellular signalling DUF3522 PF12036.3 KEG11931.1 - 8.4e-55 185.4 7.8 1e-54 185.1 5.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) Mito_morph_reg PF14972.1 KEG11931.1 - 0.048 13.0 0.2 0.074 12.4 0.2 1.3 1 0 0 1 1 1 0 Mitochondrial morphogenesis regulator Ceramidase PF05875.7 KEG11931.1 - 5.9 5.9 11.9 0.4 9.7 0.3 2.6 2 1 0 2 2 2 0 Ceramidase Armet PF10208.4 KEG11932.1 - 0.00069 19.2 0.0 0.00097 18.8 0.0 1.2 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding SAP PF02037.22 KEG11932.1 - 0.14 11.7 0.1 0.36 10.3 0.1 1.8 1 1 0 1 1 1 0 SAP domain HhH-GPD PF00730.20 KEG11934.1 - 0.0037 17.5 1.9 0.01 16.1 0.3 2.5 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein zf-C3HC4_3 PF13920.1 KEG11934.1 - 0.38 10.4 1.9 0.47 10.1 0.3 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KEG11934.1 - 3.6 7.7 5.8 8.6 6.5 3.4 2.2 1 1 1 2 2 2 0 RING-H2 zinc finger RHSP PF07999.6 KEG11935.1 - 6.8e-95 318.2 0.1 1.3e-94 317.3 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon hot spot protein DEAD PF00270.24 KEG11936.1 - 1.9e-34 118.5 0.0 4e-34 117.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEG11936.1 - 1.5e-21 76.0 0.0 7.1e-21 73.8 0.0 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 KEG11936.1 - 3.5e-18 64.8 0.0 9.9e-18 63.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 KEG11936.1 - 0.052 13.3 0.0 0.052 13.3 0.0 2.2 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit DnaJ PF00226.26 KEG11937.1 - 1.8e-18 66.0 0.3 3.6e-18 65.0 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain Pkinase PF00069.20 KEG11939.1 - 1.1e-39 136.1 0.0 2e-39 135.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG11939.1 - 9.6e-22 77.2 0.0 1.8e-21 76.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG11939.1 - 1.2e-06 27.7 0.0 2.9e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Kinase-like TGS PF02824.16 KEG11939.1 - 0.0016 18.2 0.4 0.39 10.5 0.1 2.5 2 0 0 2 2 2 2 TGS domain IL4 PF00727.13 KEG11939.1 - 0.0078 16.0 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 Interleukin 4 APH PF01636.18 KEG11939.1 - 0.026 14.2 0.9 0.082 12.6 0.1 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KEG11939.1 - 0.11 11.2 0.0 0.23 10.2 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 zf-RING_4 PF14570.1 KEG11939.1 - 0.17 11.5 14.2 0.33 10.5 9.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RIIa PF02197.12 KEG11940.1 - 2.3e-10 39.6 4.6 3.7e-10 39.0 0.1 2.8 3 0 0 3 3 3 1 Regulatory subunit of type II PKA R-subunit EF-hand_7 PF13499.1 KEG11940.1 - 0.0013 18.8 0.3 0.035 14.2 0.0 2.7 2 1 0 2 2 2 1 EF-hand domain pair TPR_11 PF13414.1 KEG11941.1 - 2.7e-14 52.5 6.7 0.0027 17.3 0.0 4.5 2 1 1 4 4 4 4 TPR repeat TPR_16 PF13432.1 KEG11941.1 - 3.1e-12 46.7 11.1 2.7e-05 24.6 0.6 4.3 3 2 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEG11941.1 - 1.2e-11 43.5 2.7 0.047 13.6 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 KEG11941.1 - 3.3e-09 36.9 9.9 0.00025 21.2 0.1 4.4 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 KEG11941.1 - 1.4e-07 30.8 0.9 0.58 9.8 0.1 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 KEG11941.1 - 7.4e-06 25.8 13.5 0.95 9.4 0.1 5.0 2 2 2 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.1 KEG11941.1 - 4.6e-05 23.6 14.6 0.015 15.8 0.1 6.3 3 3 5 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.1 KEG11941.1 - 0.00022 21.1 4.0 10 6.6 0.0 5.7 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEG11941.1 - 0.0018 17.9 6.1 0.67 9.8 0.0 5.0 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 KEG11941.1 - 0.011 14.7 3.0 0.79 8.7 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEG11941.1 - 0.016 15.6 4.8 29 5.3 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 KEG11941.1 - 0.078 13.4 0.9 55 4.6 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 KEG11941.1 - 0.15 11.9 1.0 0.6 10.0 0.1 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_21 PF09976.4 KEG11941.1 - 7.7 6.4 7.6 12 5.7 0.1 3.4 2 1 1 4 4 4 0 Tetratricopeptide repeat SF3b10 PF07189.6 KEG11943.1 - 2.2e-11 43.4 0.0 2.4e-11 43.3 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) SseB PF07179.7 KEG11944.1 - 0.0039 16.9 0.0 3.2 7.5 0.0 2.4 2 0 0 2 2 2 2 SseB protein N-terminal domain HD_3 PF13023.1 KEG11945.1 - 2.6e-38 131.3 0.0 3e-38 131.1 0.0 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 KEG11945.1 - 5.1e-06 26.4 0.0 1.1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 HD domain PAP1 PF08601.5 KEG11947.1 - 0.39 10.3 15.1 0.43 10.2 9.9 1.4 1 1 0 1 1 1 0 Transcription factor PAP1 RRM_1 PF00076.17 KEG11948.1 - 7.8e-74 243.2 0.0 1.4e-17 63.0 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG11948.1 - 1.1e-50 169.5 0.0 8.3e-12 44.9 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG11948.1 - 7.2e-29 99.4 0.0 5e-08 32.6 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KEG11948.1 - 2.6e-10 40.0 5.8 0.03 14.1 0.6 4.3 2 1 2 4 4 4 4 RNA binding motif Nup35_RRM_2 PF14605.1 KEG11948.1 - 2.5e-07 30.3 0.1 0.51 10.1 0.0 4.5 5 0 0 5 5 5 2 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 KEG11948.1 - 1.7e-06 27.6 0.0 0.52 10.0 0.0 4.3 3 1 1 4 4 4 3 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 KEG11948.1 - 2.7e-06 27.0 1.2 0.2 11.3 0.0 4.5 3 2 1 4 4 4 2 Limkain b1 Guanylate_cyc PF00211.15 KEG11949.1 - 4.4e-46 156.5 0.0 8e-46 155.7 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Peripla_BP_6 PF13458.1 KEG11949.1 - 2.5e-13 50.0 5.7 6.1e-09 35.6 1.2 3.0 2 1 0 2 2 2 2 Periplasmic binding protein PIGA PF08288.7 KEG11950.1 - 2.7e-35 120.6 0.1 4.9e-35 119.7 0.0 1.4 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 KEG11950.1 - 4.9e-28 97.6 0.0 1.6e-27 96.0 0.0 1.7 1 1 1 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KEG11950.1 - 1.2e-17 64.1 0.4 3.1e-17 62.8 0.3 1.7 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 KEG11950.1 - 1.5e-17 64.1 0.8 2.8e-17 63.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 KEG11950.1 - 1e-11 45.1 0.0 3e-11 43.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 KEG11950.1 - 1.8e-05 24.6 0.0 4.7e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 KEG11950.1 - 0.0015 18.7 0.0 0.004 17.4 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 mRNA_stabil PF13929.1 KEG11951.1 - 0.03 13.2 0.0 0.037 12.9 0.0 1.1 1 0 0 1 1 1 0 mRNA stabilisation HEAT_2 PF13646.1 KEG11951.1 - 0.075 13.3 4.4 0.15 12.3 3.1 1.6 1 1 0 1 1 1 0 HEAT repeats PSK_trans_fac PF07704.6 KEG11951.1 - 0.33 11.6 3.9 0.33 11.6 0.7 2.0 2 0 0 2 2 2 0 Rv0623-like transcription factor DNA_pol_B PF00136.16 KEG11952.1 - 6.4e-138 460.4 0.0 8.9e-138 459.9 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KEG11952.1 - 3.2e-73 246.4 0.0 5.2e-73 245.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KEG11952.1 - 1.5e-20 72.9 7.9 1.5e-20 72.9 5.5 2.0 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta SNF2_N PF00176.18 KEG11953.1 - 2.3e-77 259.7 0.1 4.7e-77 258.7 0.1 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 KEG11953.1 - 2.5e-22 78.8 0.4 6.7e-22 77.4 0.3 1.8 1 0 0 1 1 1 1 SLIDE Helicase_C PF00271.26 KEG11953.1 - 3.8e-16 58.6 0.0 1e-15 57.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEG11953.1 - 8.4e-07 28.6 0.0 1.6e-05 24.4 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.10 KEG11953.1 - 0.00017 21.4 1.5 0.0017 18.1 0.0 3.2 2 2 1 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 KEG11953.1 - 0.00098 18.0 0.0 0.0042 15.9 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 RRM_1 PF00076.17 KEG11953.1 - 0.081 12.5 0.1 1.9 8.2 0.0 2.9 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mu-like_Pro PF10123.4 KEG11953.1 - 0.15 11.5 4.3 0.25 10.7 2.0 2.0 2 0 0 2 2 2 0 Mu-like prophage I protein HAND PF09110.6 KEG11953.1 - 2.3 8.6 17.0 0.093 13.1 7.0 2.4 3 0 0 3 3 3 0 HAND Pkinase PF00069.20 KEG11954.1 - 8.1e-66 221.8 0.0 1.3e-65 221.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG11954.1 - 6.7e-37 126.9 0.0 1e-36 126.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.1 KEG11954.1 - 5.6e-15 55.2 0.1 1.1e-07 31.9 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KEG11954.1 - 2.8e-13 48.1 0.3 0.0062 15.7 0.0 5.1 4 1 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 KEG11954.1 - 3e-12 45.3 2.2 0.05 13.5 0.0 5.8 5 1 1 6 6 6 4 EF-hand domain EF-hand_8 PF13833.1 KEG11954.1 - 7.5e-12 44.6 0.2 8e-06 25.3 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair Kinase-like PF14531.1 KEG11954.1 - 9.4e-05 21.5 0.0 0.00017 20.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like EF-hand_5 PF13202.1 KEG11954.1 - 0.0005 19.2 0.9 3.1 7.2 0.0 4.1 4 0 0 4 4 4 1 EF hand Kdo PF06293.9 KEG11954.1 - 0.00064 18.8 0.1 0.0013 17.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family F-actin_cap_A PF01267.12 KEG11954.1 - 0.0012 17.9 0.4 0.0019 17.2 0.2 1.3 1 0 0 1 1 1 1 F-actin capping protein alpha subunit RIO1 PF01163.17 KEG11954.1 - 0.0039 16.5 0.2 0.0092 15.3 0.1 1.5 1 0 0 1 1 1 1 RIO1 family PMBR PF09373.5 KEG11954.1 - 0.08 12.9 0.0 0.33 10.9 0.0 2.1 2 0 0 2 2 2 0 Pseudomurein-binding repeat APH PF01636.18 KEG11954.1 - 0.087 12.5 0.1 0.34 10.6 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family SPARC_Ca_bdg PF10591.4 KEG11954.1 - 0.12 12.3 1.0 2 8.5 0.1 2.8 1 1 2 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region TPR_12 PF13424.1 KEG11955.1 - 1.3e-19 69.8 10.7 2.8e-09 36.7 0.9 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEG11955.1 - 3e-11 42.3 13.5 0.078 12.9 0.2 6.2 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 KEG11955.1 - 6.1e-11 41.4 10.4 0.067 12.8 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 KEG11955.1 - 9.1e-08 31.6 14.9 0.0011 18.5 0.4 4.1 1 1 5 6 6 6 5 TPR repeat TPR_8 PF13181.1 KEG11955.1 - 4.6e-07 29.1 4.8 0.0017 17.9 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEG11955.1 - 4.5e-05 22.9 10.0 1.3 9.0 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEG11955.1 - 0.00043 20.8 9.9 0.18 12.4 0.1 4.4 2 2 2 4 4 4 2 Tetratricopeptide repeat RPN7 PF10602.4 KEG11955.1 - 0.0015 17.9 1.1 2.2 7.6 0.0 3.1 2 1 1 3 3 3 2 26S proteasome subunit RPN7 TPR_9 PF13371.1 KEG11955.1 - 0.016 15.0 0.0 0.016 15.0 0.0 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF2225 PF09986.4 KEG11955.1 - 0.021 14.3 0.0 0.62 9.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_10 PF13374.1 KEG11955.1 - 0.053 13.4 8.8 2.6 8.0 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEG11955.1 - 0.12 13.1 9.8 14 6.6 0.1 4.9 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_21 PF09976.4 KEG11955.1 - 1 9.2 5.8 1.3 8.9 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 KEG11955.1 - 1.7 9.3 6.2 17 6.1 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEG11955.1 - 4.3 8.0 8.2 2.2 8.9 0.0 4.3 6 0 0 6 6 4 0 Tetratricopeptide repeat AAA_assoc PF14363.1 KEG11956.1 - 0.0059 16.6 0.0 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 Domain associated at C-terminal with AAA Autophagy_N PF03986.8 KEG11957.1 - 2.9e-35 121.1 2.0 4.4e-35 120.5 1.4 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 KEG11957.1 - 1e-22 80.0 0.8 2e-22 79.1 0.6 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 KEG11957.1 - 4.2e-12 44.9 1.3 8.4e-12 43.9 0.9 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal SDA1 PF05285.7 KEG11957.1 - 0.07 12.4 1.6 0.088 12.0 1.1 1.2 1 0 0 1 1 1 0 SDA1 CHAT PF12770.2 KEG11959.1 - 1.9e-37 128.9 0.6 3.6e-37 128.0 0.4 1.5 1 0 0 1 1 1 1 CHAT domain LRR_6 PF13516.1 KEG11959.1 - 0.0039 17.1 1.5 34 4.9 0.0 4.3 4 0 0 4 4 4 2 Leucine Rich repeat AAA_13 PF13166.1 KEG11960.1 - 1.2 7.5 9.0 1.5 7.2 6.2 1.0 1 0 0 1 1 1 0 AAA domain Phage_int_SAM_5 PF13102.1 KEG11960.1 - 5.6 6.9 6.2 17 5.3 4.3 2.0 1 1 0 1 1 1 0 Phage integrase SAM-like domain DUF3138 PF11336.3 KEG11960.1 - 6.6 4.7 14.1 1.2 7.1 2.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) Lebercilin PF15619.1 KEG11960.1 - 6.8 6.0 24.2 0.17 11.3 10.0 2.0 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease LRR_4 PF12799.2 KEG11962.1 - 1.7e-23 81.7 2.9 0.0082 15.7 0.0 9.5 8 3 3 11 11 11 7 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KEG11962.1 - 2e-20 70.5 26.2 0.0024 17.7 0.1 11.6 14 0 0 14 14 14 5 Leucine Rich repeat LRR_1 PF00560.28 KEG11962.1 - 2e-13 48.3 18.0 2.1 8.6 0.0 11.7 12 0 0 12 12 12 4 Leucine Rich Repeat LRR_8 PF13855.1 KEG11962.1 - 1.3e-12 47.2 22.0 0.04 13.6 0.2 10.3 7 3 3 10 10 10 5 Leucine rich repeat LRR_7 PF13504.1 KEG11962.1 - 2e-07 30.0 27.1 11 6.7 0.1 12.2 12 1 0 12 12 12 2 Leucine rich repeat DAP10 PF07213.6 KEG11962.1 - 0.069 12.9 3.6 7.3 6.4 1.7 3.0 2 0 0 2 2 2 0 DAP10 membrane protein Glycolipid_bind PF06475.6 KEG11962.1 - 0.074 12.1 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative glycolipid-binding Pkinase PF00069.20 KEG11963.1 - 3.9e-37 127.8 0.0 5.3e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG11963.1 - 2.6e-13 49.6 0.0 3e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG11963.1 - 0.0026 16.7 0.0 0.0062 15.5 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.20 KEG11965.1 - 3.3e-52 177.2 0.0 5.1e-52 176.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG11965.1 - 3.1e-34 118.2 0.0 5.1e-34 117.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Guanylate_cyc PF00211.15 KEG11965.1 - 0.00016 21.0 0.0 0.00034 20.0 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Kinase-like PF14531.1 KEG11965.1 - 0.0025 16.8 0.0 0.0045 15.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KEG11965.1 - 0.013 14.5 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SpoIISA_toxin PF14171.1 KEG11966.1 - 0.066 12.4 0.1 0.07 12.3 0.0 1.0 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system TrbL PF04610.9 KEG11967.1 - 0.014 15.0 0.2 0.022 14.4 0.1 1.2 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein Aa_trans PF01490.13 KEG11970.1 - 8.4e-45 152.9 30.3 2.5e-44 151.3 21.0 1.6 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Halogen_Hydrol PF10112.4 KEG11970.1 - 6.5 6.1 4.9 4.9 6.5 0.6 2.5 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Herpes_U44 PF04533.8 KEG11971.1 - 0.048 12.9 0.2 0.075 12.2 0.1 1.2 1 0 0 1 1 1 0 Herpes virus U44 protein EVC2_like PF12297.3 KEG11971.1 - 4.3 5.8 9.4 8 4.9 6.5 1.4 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein PAP_assoc PF03828.14 KEG11972.1 - 2.1e-07 30.7 0.2 4.9e-07 29.5 0.2 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KEG11972.1 - 0.022 15.0 0.0 0.067 13.5 0.0 1.8 1 0 0 1 1 1 0 Nucleotidyltransferase domain DKCLD PF08068.7 KEG11973.1 - 1.8e-27 94.9 0.1 6.6e-26 90.0 0.0 2.6 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 KEG11973.1 - 6.2e-23 81.6 1.5 1.7e-19 70.4 1.0 3.1 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 KEG11973.1 - 3.9e-19 68.1 0.8 7.7e-19 67.1 0.3 1.7 2 0 0 2 2 2 1 PUA domain ATP-synt PF00231.14 KEG11974.1 - 6.7e-32 111.0 3.9 7.6e-32 110.8 2.7 1.0 1 0 0 1 1 1 1 ATP synthase Adaptin_binding PF10199.4 KEG11974.1 - 0.042 14.1 0.0 0.053 13.8 0.0 1.3 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Ribosomal_S6e PF01092.14 KEG11975.1 - 3.4e-40 136.5 0.3 3.4e-40 136.5 0.2 2.3 3 0 0 3 3 3 1 Ribosomal protein S6e ATP-synt_C PF00137.16 KEG11976.1 - 1.6e-25 88.7 37.5 3e-18 65.4 7.8 3.0 3 0 0 3 3 3 2 ATP synthase subunit C TF_Otx PF03529.8 KEG11976.1 - 0.047 13.9 0.4 0.047 13.9 0.3 1.6 2 0 0 2 2 2 0 Otx1 transcription factor GerA PF03323.8 KEG11976.1 - 0.2 9.7 4.1 1.7 6.6 0.5 2.2 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein DUF4064 PF13273.1 KEG11976.1 - 5.6 7.1 10.4 2.5 8.2 1.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Flavi_NS4A PF01350.12 KEG11976.1 - 8.2 5.9 8.1 17 4.9 0.1 2.5 2 1 0 2 2 2 0 Flavivirus non-structural protein NS4A Gaa1 PF04114.9 KEG11977.1 - 2.6e-06 26.4 1.0 3.2e-06 26.1 0.2 1.4 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component Ribosomal_L37ae PF01780.14 KEG11978.1 - 4.2e-36 122.6 4.9 4.7e-36 122.5 3.4 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family C1_1 PF00130.17 KEG11978.1 - 0.00085 18.9 1.8 0.0012 18.4 1.2 1.2 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) A2L_zn_ribbon PF08792.5 KEG11978.1 - 0.025 14.0 0.9 2.5 7.6 0.0 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain UPF0547 PF10571.4 KEG11978.1 - 0.052 13.2 1.2 6.8 6.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Zn_Tnp_IS1595 PF12760.2 KEG11978.1 - 0.099 12.4 2.4 0.16 11.8 1.7 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Carla_C4 PF01623.12 KEG11978.1 - 0.12 12.1 1.6 0.14 11.9 1.1 1.4 1 1 0 1 1 1 0 Carlavirus putative nucleic acid binding protein NOB1_Zn_bind PF08772.6 KEG11978.1 - 0.12 12.2 3.6 1.2 8.9 2.5 2.2 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zf-HIT PF04438.11 KEG11978.1 - 0.21 11.2 2.6 0.24 11.0 0.3 1.9 2 0 0 2 2 2 0 HIT zinc finger GFA PF04828.9 KEG11978.1 - 0.34 10.8 2.8 1.1 9.2 0.3 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-C4_ClpX PF06689.8 KEG11978.1 - 7 6.2 6.7 1.3 8.5 1.9 1.8 2 0 0 2 2 2 0 ClpX C4-type zinc finger Proteasome PF00227.21 KEG11979.1 - 1.4e-56 190.8 0.0 1.7e-56 190.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KEG11979.1 - 6.5e-14 50.9 0.0 2.2e-13 49.2 0.0 2.0 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature NblA PF04485.7 KEG11979.1 - 0.074 12.9 0.2 0.13 12.1 0.2 1.3 1 0 0 1 1 1 0 Phycobilisome degradation protein nblA Glyco_hydro_67C PF07477.7 KEG11979.1 - 0.098 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 C-terminus DUF2866 PF11065.3 KEG11979.1 - 0.1 12.5 0.1 0.24 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2866) Pex14_N PF04695.8 KEG11980.1 - 3.1e-25 88.7 0.0 3.1e-25 88.7 0.0 2.6 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region IncA PF04156.9 KEG11980.1 - 0.0031 17.1 1.0 0.0047 16.5 0.7 1.4 1 0 0 1 1 1 1 IncA protein E2R135 PF11570.3 KEG11980.1 - 0.033 14.2 1.9 0.067 13.2 1.3 1.5 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 TMCO5 PF14992.1 KEG11980.1 - 0.035 13.2 1.9 0.059 12.5 1.3 1.2 1 0 0 1 1 1 0 TMCO5 family Lipoprotein_16 PF03923.8 KEG11980.1 - 0.059 12.7 1.1 0.15 11.4 0.8 1.6 1 0 0 1 1 1 0 Uncharacterized lipoprotein DUF3584 PF12128.3 KEG11980.1 - 0.18 9.0 5.2 0.26 8.5 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Mnd1 PF03962.10 KEG11980.1 - 0.24 11.0 5.8 0.46 10.1 4.0 1.4 1 0 0 1 1 1 0 Mnd1 family DUF4404 PF14357.1 KEG11980.1 - 1.5 9.2 8.5 0.28 11.6 1.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) DUF4164 PF13747.1 KEG11980.1 - 2.4 8.3 11.8 0.1 12.7 3.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) ADIP PF11559.3 KEG11980.1 - 3.4 7.5 10.6 7.3 6.4 7.3 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4424 PF14415.1 KEG11981.1 - 0.0085 15.6 0.1 0.015 14.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4424) BolA PF01722.13 KEG11982.1 - 5.7e-18 64.6 0.0 6.4e-18 64.4 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein Ribosomal_L32e PF01655.13 KEG11984.1 - 4.6e-42 142.5 0.7 5.5e-42 142.2 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 DUF1436 PF07262.6 KEG11984.1 - 0.079 12.4 0.0 0.095 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1436) SH3_9 PF14604.1 KEG11985.1 - 1e-34 117.8 1.3 7.5e-14 51.0 0.0 3.8 4 0 0 4 4 4 3 Variant SH3 domain SH3_1 PF00018.23 KEG11985.1 - 5.8e-32 108.8 0.0 1.2e-11 43.7 0.0 3.5 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.12 KEG11985.1 - 1.4e-30 104.5 0.3 4.3e-11 42.1 0.1 3.2 3 0 0 3 3 3 3 Variant SH3 domain DUF4205 PF13898.1 KEG11986.1 - 5.7e-20 71.3 0.0 1.1e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) DUF4636 PF15468.1 KEG11986.1 - 0.13 11.7 2.4 0.22 10.9 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) NIF PF03031.13 KEG11987.1 - 3.9e-33 114.3 0.0 7.1e-33 113.5 0.0 1.4 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 KEG11987.1 - 0.12 12.5 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Spc7 PF08317.6 KEG11988.1 - 0.0012 17.5 4.9 0.0012 17.5 3.4 14.2 11 2 2 13 13 13 4 Spc7 kinetochore protein ADIP PF11559.3 KEG11988.1 - 0.0027 17.6 2.2 0.0027 17.6 1.6 23.3 14 7 12 26 26 26 9 Afadin- and alpha -actinin-Binding zf-RING_2 PF13639.1 KEG11989.1 - 4.8e-13 48.6 9.9 7.7e-13 48.0 6.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KEG11989.1 - 4.8e-10 39.4 3.8 9.9e-10 38.3 2.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KEG11989.1 - 2.5e-07 30.2 8.8 3.7e-07 29.7 6.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEG11989.1 - 4.7e-07 29.3 10.9 7.5e-07 28.7 7.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEG11989.1 - 9.4e-07 28.7 10.9 1.4e-06 28.1 7.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KEG11989.1 - 1.5e-05 24.7 2.0 2.9e-05 23.8 1.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 KEG11989.1 - 3.8e-05 23.3 8.8 5.9e-05 22.7 6.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KEG11989.1 - 0.0016 18.0 7.3 0.013 15.2 5.3 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.1 KEG11989.1 - 0.0023 17.4 7.3 0.0038 16.7 5.0 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RINGv PF12906.2 KEG11989.1 - 0.096 12.7 10.7 0.16 12.0 7.4 1.3 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.1 KEG11989.1 - 0.1 12.3 7.5 0.46 10.2 5.3 1.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.24 KEG11989.1 - 0.1 12.2 8.0 0.21 11.3 5.5 1.5 1 1 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.1 KEG11989.1 - 0.18 11.7 6.4 0.43 10.4 4.4 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Baculo_RING PF05883.6 KEG11989.1 - 0.24 11.2 1.8 0.51 10.1 1.3 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain FANCL_C PF11793.3 KEG11989.1 - 1.5 8.8 6.1 4.1 7.4 4.2 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.6 KEG11989.1 - 4.2 7.4 9.0 7.2 6.6 6.3 1.4 1 0 0 1 1 1 0 RING-like domain DUF1242 PF06842.7 KEG11990.1 - 4.1e-14 51.7 0.3 6e-14 51.2 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) DnaJ PF00226.26 KEG11992.1 - 3.3e-09 36.3 0.1 6.1e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain zf-CCCH PF00642.19 KEG11992.1 - 3.4 7.4 8.0 0.24 11.1 2.1 1.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ribosomal_L7Ae PF01248.21 KEG11993.1 - 6.2e-25 86.5 0.0 7e-25 86.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RRM_6 PF14259.1 KEG11994.1 - 0.0058 16.5 0.5 0.056 13.4 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG11994.1 - 0.0092 15.8 0.1 0.02 14.6 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ArfGap PF01412.13 KEG11995.1 - 2.1e-22 79.0 0.3 6e-22 77.6 0.0 1.9 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PMG PF05287.7 KEG11996.1 - 0.052 13.3 0.0 0.072 12.8 0.0 1.2 1 0 0 1 1 1 0 PMG protein Lamprin PF06403.6 KEG11996.1 - 0.08 12.6 58.2 0.016 14.9 12.5 3.1 1 1 2 3 3 3 0 Lamprin EBP50_C-term PF09007.6 KEG11997.1 - 0.062 13.1 0.5 0.16 11.8 0.4 1.7 1 0 0 1 1 1 0 EBP50, C-terminal SinI PF08671.5 KEG11997.1 - 0.078 12.4 0.2 0.17 11.3 0.1 1.5 1 0 0 1 1 1 0 Anti-repressor SinI Vfa1 PF08432.5 KEG11997.1 - 0.34 10.9 2.8 0.49 10.3 2.0 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Coq4 PF05019.8 KEG11998.1 - 7.9e-75 250.5 0.0 9.8e-75 250.2 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 TF_Zn_Ribbon PF08271.7 KEG11998.1 - 0.0091 15.3 0.0 0.023 13.9 0.0 1.7 2 0 0 2 2 2 1 TFIIB zinc-binding DUF1289 PF06945.8 KEG11998.1 - 0.042 13.3 0.9 0.086 12.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) DnaJ PF00226.26 KEG12000.1 - 3.4e-12 45.9 0.0 7.1e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Rhodanese PF00581.15 KEG12001.1 - 1.2e-11 44.9 0.0 1.4e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain NA37 PF04245.8 KEG12001.1 - 0.016 14.5 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 37-kD nucleoid-associated bacterial protein Rhodanese PF00581.15 KEG12002.1 - 6e-12 45.9 0.0 7.6e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese PF00581.15 KEG12003.1 - 3.3e-14 53.1 0.0 4.2e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Tet_JBP PF12851.2 KEG12004.1 - 2.4e-28 98.5 0.0 4.4e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Rsm22 PF09243.5 KEG12004.1 - 0.048 12.6 0.0 0.079 11.9 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Cyt-b5 PF00173.23 KEG12005.1 - 5.6e-22 77.3 0.1 7.3e-22 76.9 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ribosomal_L34e PF01199.13 KEG12006.1 - 0.035 14.3 2.4 0.054 13.7 1.7 1.3 1 0 0 1 1 1 0 Ribosomal protein L34e GEMIN8 PF15348.1 KEG12007.1 - 0.0018 18.3 1.1 0.0046 17.0 0.8 1.6 1 0 0 1 1 1 1 Gemini of Cajal bodies-associated protein 8 Laminin_G_2 PF02210.19 KEG12007.1 - 0.0055 16.7 0.0 0.094 12.7 0.0 2.5 2 0 0 2 2 2 1 Laminin G domain IQ PF00612.22 KEG12007.1 - 0.0081 15.7 1.6 0.028 14.0 1.1 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif LRR_6 PF13516.1 KEG12008.1 - 1.6e-14 52.2 0.0 0.19 11.9 0.0 6.8 7 0 0 7 7 7 4 Leucine Rich repeat DDDD PF10161.4 KEG12008.1 - 0.014 14.9 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 Putative mitochondrial precursor protein EF-hand_7 PF13499.1 KEG12009.1 - 2.5e-11 43.5 2.4 4.5e-07 29.9 0.4 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KEG12009.1 - 7.1e-08 31.2 4.5 0.0023 17.0 0.1 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 KEG12009.1 - 6.2e-07 28.7 5.8 0.0072 16.1 0.1 3.8 2 1 2 4 4 4 2 EF-hand domain EF-hand_5 PF13202.1 KEG12009.1 - 2.2e-06 26.7 6.2 0.0065 15.7 0.1 3.2 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 KEG12009.1 - 6.8e-06 25.6 2.3 0.004 16.7 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair RIIa PF02197.12 KEG12009.1 - 1.9e-05 23.9 1.7 0.00055 19.3 0.0 2.7 3 0 0 3 3 3 1 Regulatory subunit of type II PKA R-subunit TPT PF03151.11 KEG12010.1 - 2.6e-10 40.1 13.4 2.6e-10 40.1 9.3 2.8 1 1 1 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 KEG12010.1 - 2.7e-07 30.6 28.9 0.00026 21.0 7.2 2.4 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 KEG12010.1 - 0.0047 15.9 23.3 0.0081 15.1 16.2 1.4 1 1 0 1 1 1 1 UAA transporter family HOOK PF05622.7 KEG12011.1 - 0.0035 15.2 2.3 0.0035 15.2 1.6 4.9 1 1 4 5 5 5 2 HOOK protein Seryl_tRNA_N PF02403.17 KEG12011.1 - 0.0093 15.9 8.4 0.0093 15.9 5.8 8.6 3 2 3 7 7 7 3 Seryl-tRNA synthetase N-terminal domain DUF1192 PF06698.6 KEG12011.1 - 0.19 11.5 0.1 0.19 11.5 0.1 6.9 8 0 0 8 8 8 0 Protein of unknown function (DUF1192) FAM176 PF14851.1 KEG12012.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 FAM176 family TPT PF03151.11 KEG12013.1 - 3.4e-08 33.2 8.7 3.4e-08 33.2 6.1 3.1 1 1 2 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 KEG12013.1 - 0.0057 16.6 24.7 0.027 14.5 3.9 3.4 2 1 0 3 3 3 2 EamA-like transporter family NIF PF03031.13 KEG12015.1 - 5.5e-28 97.6 0.0 9.4e-19 67.6 0.0 2.2 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase VP40 PF07447.7 KEG12015.1 - 0.058 12.4 0.0 0.13 11.3 0.0 1.6 1 0 0 1 1 1 0 Matrix protein VP40 Brix PF04427.13 KEG12016.1 - 3.6e-44 150.7 0.1 5.2e-44 150.1 0.0 1.2 1 0 0 1 1 1 1 Brix domain DUF1682 PF07946.9 KEG12016.1 - 1.4 7.6 7.8 2.1 7.1 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Pyrophosphatase PF00719.14 KEG12017.1 - 4.4e-35 120.4 0.0 4.9e-35 120.2 0.0 1.0 1 0 0 1 1 1 1 Inorganic pyrophosphatase Got1 PF04178.7 KEG12018.1 - 2.1e-30 105.2 16.9 2.8e-30 104.8 11.7 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family zf-LYAR PF08790.6 KEG12019.1 - 9.5e-15 53.9 4.1 9.5e-15 53.9 2.8 2.1 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger DUF2067 PF09840.4 KEG12019.1 - 0.059 12.8 0.1 0.078 12.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2067) DM PF00751.13 KEG12019.1 - 0.077 12.5 0.7 0.17 11.3 0.5 1.6 1 0 0 1 1 1 0 DM DNA binding domain RRM_1 PF00076.17 KEG12020.1 - 1.2e-35 120.9 0.0 6.2e-12 44.9 0.0 3.3 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG12020.1 - 6.3e-29 99.7 0.1 2.4e-09 37.0 0.0 3.4 2 1 1 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG12020.1 - 5.2e-17 61.4 0.0 4.9e-11 42.3 0.0 3.4 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEG12022.1 - 7.8e-31 105.5 0.0 1.5e-19 69.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG12022.1 - 7.4e-26 89.9 0.0 2.7e-14 52.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG12022.1 - 4.3e-14 52.1 0.0 1.6e-08 34.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KEG12022.1 - 0.0027 17.4 0.0 0.52 10.1 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.6 KEG12022.1 - 0.0077 16.1 0.0 0.34 10.9 0.0 2.5 2 0 0 2 2 2 1 RNA binding domain Limkain-b1 PF11608.3 KEG12022.1 - 0.034 13.8 0.0 0.08 12.7 0.0 1.7 1 0 0 1 1 1 0 Limkain b1 tRNA-synt_2c PF01411.14 KEG12024.1 - 2.3e-193 643.4 0.0 2.9e-193 643.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 KEG12024.1 - 3.2e-10 39.7 0.0 8.4e-10 38.3 0.0 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 KEG12024.1 - 0.00014 21.5 3.0 0.00049 19.7 2.1 2.0 1 0 0 1 1 1 1 DHHA1 domain CoaE PF01121.15 KEG12025.1 - 1.3e-43 148.4 0.0 3.4e-43 147.1 0.0 1.6 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 KEG12025.1 - 1.4e-06 29.1 0.0 1.9e-06 28.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KEG12025.1 - 0.00031 20.6 0.4 0.0016 18.3 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KEG12025.1 - 0.0039 17.5 0.2 0.043 14.1 0.2 2.1 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 KEG12025.1 - 0.014 15.2 0.1 0.029 14.2 0.0 1.8 1 1 1 2 2 2 0 Shikimate kinase PRK PF00485.13 KEG12025.1 - 0.03 13.8 0.4 0.4 10.1 0.0 2.4 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family Cytidylate_kin2 PF13189.1 KEG12025.1 - 0.11 12.3 0.2 5.6 6.8 0.2 2.2 2 0 0 2 2 2 0 Cytidylate kinase-like family Ribosomal_L14e PF01929.12 KEG12026.1 - 6.6e-23 80.8 4.5 6.6e-23 80.8 3.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L14 KOW PF00467.24 KEG12026.1 - 1.9e-06 27.3 0.6 3.2e-06 26.6 0.4 1.4 1 0 0 1 1 1 1 KOW motif HA2 PF04408.18 KEG12029.1 - 1.7e-15 56.8 0.1 1.7e-15 56.8 0.0 1.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KEG12029.1 - 3.6e-10 39.5 0.0 9.8e-10 38.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain R3H PF01424.17 KEG12029.1 - 4.3e-10 39.1 0.0 1.4e-09 37.4 0.0 1.9 1 0 0 1 1 1 1 R3H domain DEAD PF00270.24 KEG12029.1 - 8.9e-08 31.8 0.1 2.1e-07 30.5 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KEG12029.1 - 0.0014 18.7 0.0 0.0043 17.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KEG12029.1 - 0.0034 16.3 0.0 0.0061 15.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF3295 PF11702.3 KEG12029.1 - 0.02 13.9 2.3 37 3.1 5.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3295) AAA_19 PF13245.1 KEG12029.1 - 0.04 13.6 0.0 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain Miro PF08477.8 KEG12029.1 - 0.12 12.8 0.0 0.4 11.1 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein Metallophos PF00149.23 KEG12030.1 - 1.2e-08 34.5 1.2 2.1e-08 33.7 0.8 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KEG12030.1 - 0.1 12.4 0.3 0.54 10.0 0.2 2.1 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Myosin_tail_1 PF01576.14 KEG12033.1 - 0.024 12.4 4.0 0.03 12.0 2.8 1.0 1 0 0 1 1 1 0 Myosin tail Mod_r PF07200.8 KEG12033.1 - 0.038 13.9 4.8 0.044 13.7 3.0 1.4 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Poty_PP PF08440.5 KEG12033.1 - 0.043 12.8 2.2 0.054 12.5 1.5 1.1 1 0 0 1 1 1 0 Potyviridae polyprotein Apt1 PF10351.4 KEG12033.1 - 0.053 12.3 0.4 0.05 12.4 0.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF3501 PF12007.3 KEG12033.1 - 0.073 12.7 1.0 0.081 12.5 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3501) Pyr_excise PF03013.9 KEG12033.1 - 0.085 12.6 2.3 0.12 12.1 1.6 1.2 1 0 0 1 1 1 0 Pyrimidine dimer DNA glycosylase V_ATPase_I PF01496.14 KEG12033.1 - 0.09 10.6 1.6 0.093 10.5 1.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cast PF10174.4 KEG12033.1 - 0.23 9.4 6.6 0.28 9.1 4.6 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone bZIP_2 PF07716.10 KEG12033.1 - 0.31 10.8 6.2 0.7 9.7 2.2 2.4 2 0 0 2 2 2 0 Basic region leucine zipper Prefoldin_2 PF01920.15 KEG12033.1 - 0.7 9.6 9.1 0.088 12.5 1.8 2.0 1 1 1 2 2 2 0 Prefoldin subunit DUF3450 PF11932.3 KEG12033.1 - 0.9 8.7 7.0 1.2 8.3 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF724 PF05266.9 KEG12033.1 - 1.4 8.4 6.6 1.9 8.0 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Sds3 PF08598.6 KEG12033.1 - 1.9 7.9 7.1 1.6 8.2 0.6 2.0 1 1 1 2 2 2 0 Sds3-like DUF904 PF06005.7 KEG12033.1 - 8.3 6.7 11.1 54 4.1 7.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Hist_deacetyl PF00850.14 KEG12035.1 - 1.1e-67 228.4 0.0 1.5e-67 228.1 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain EF-hand_1 PF00036.27 KEG12036.1 - 2.2e-20 70.3 4.7 4e-07 28.8 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 KEG12036.1 - 8.8e-19 65.6 2.1 0.00071 19.2 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 KEG12036.1 - 8.2e-17 61.1 8.6 4.1e-08 33.2 1.6 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KEG12036.1 - 9.7e-16 56.3 4.2 0.0016 17.7 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 KEG12036.1 - 1.4e-14 53.4 5.6 0.00071 19.1 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain pair zf-C3HC4_3 PF13920.1 KEG12036.1 - 5e-09 35.6 6.9 5e-09 35.6 4.8 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEG12036.1 - 2.7e-08 33.6 9.6 2.7e-08 33.6 6.6 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEG12036.1 - 4.2e-07 29.5 5.2 4.2e-07 29.5 3.6 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEG12036.1 - 4.4e-07 29.6 9.1 1.1e-06 28.2 6.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KEG12036.1 - 5.6e-06 25.9 9.4 5.6e-06 25.9 6.5 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.1 KEG12036.1 - 8.5e-06 25.4 4.8 1.5e-05 24.6 3.3 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein SPARC_Ca_bdg PF10591.4 KEG12036.1 - 2.9e-05 24.0 0.0 0.4 10.7 0.0 2.5 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_like PF09279.6 KEG12036.1 - 3.8e-05 23.6 0.0 7.6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like zf-C3HC4_4 PF15227.1 KEG12036.1 - 0.00034 20.4 6.2 0.00034 20.4 4.3 2.2 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KEG12036.1 - 0.00088 18.9 1.7 0.00088 18.9 1.2 2.5 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.1 KEG12036.1 - 0.0066 15.9 6.5 0.012 15.1 4.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-MIZ PF02891.15 KEG12036.1 - 2.5 7.6 10.2 6.6 6.3 5.5 2.6 2 1 0 2 2 2 0 MIZ/SP-RING zinc finger DNA_mis_repair PF01119.14 KEG12037.1 - 2.4e-25 88.2 0.0 4.6e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KEG12037.1 - 2.2e-10 40.3 0.0 4.4e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KEG12037.1 - 4.1e-07 29.6 0.0 1.4e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 KEG12037.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 MutL C terminal dimerisation domain TFIIF_alpha PF05793.7 KEG12037.1 - 0.31 9.3 2.0 0.43 8.8 1.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Kinesin PF00225.18 KEG12038.1 - 1.9e-58 197.7 0.0 1.2e-40 139.2 0.0 2.8 2 1 0 2 2 2 2 Kinesin motor domain UPF0184 PF03670.8 KEG12038.1 - 0.016 15.3 0.2 0.37 11.0 0.0 2.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) T2SE PF00437.15 KEG12038.1 - 0.032 13.1 0.0 0.069 12.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.1 KEG12038.1 - 0.48 10.5 3.6 0.23 11.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain PH PF00169.24 KEG12039.1 - 2.3e-14 53.4 0.1 4.8e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KEG12039.1 - 0.00094 19.4 0.1 0.002 18.3 0.0 1.5 1 1 0 1 1 1 1 Pleckstrin homology domain HpcH_HpaI PF03328.9 KEG12041.1 - 3.9e-07 29.1 0.0 0.00099 18.0 0.0 2.8 2 1 0 2 2 2 2 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 KEG12041.1 - 0.0018 17.1 0.0 0.0067 15.2 0.0 1.8 2 0 0 2 2 2 1 C-C_Bond_Lyase of the TIM-Barrel fold SDH_sah PF01972.11 KEG12041.1 - 0.082 11.6 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Serine dehydrogenase proteinase Pkinase PF00069.20 KEG12042.1 - 2e-62 210.7 0.0 2.5e-62 210.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG12042.1 - 1.2e-38 132.6 0.0 1.7e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase zf-ribbon_3 PF13248.1 KEG12042.1 - 4e-06 25.8 5.0 7.4e-06 24.9 3.5 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 KEG12042.1 - 9.3e-05 21.7 6.5 0.00017 20.9 4.5 1.5 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 KEG12042.1 - 0.00012 21.8 1.6 0.00024 20.8 1.1 1.4 1 0 0 1 1 1 1 Double zinc ribbon APH PF01636.18 KEG12042.1 - 0.0046 16.7 0.0 0.058 13.1 0.0 2.4 1 1 2 3 3 3 1 Phosphotransferase enzyme family zf-NADH-PPase PF09297.6 KEG12042.1 - 0.0087 15.5 3.1 0.45 10.0 0.2 2.4 2 0 0 2 2 2 2 NADH pyrophosphatase zinc ribbon domain NOB1_Zn_bind PF08772.6 KEG12042.1 - 0.07 12.9 3.4 0.16 11.7 2.3 1.5 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like UPF0547 PF10571.4 KEG12042.1 - 0.1 12.2 2.7 7.9 6.2 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-RanBP PF00641.13 KEG12042.1 - 1.1 8.4 5.5 2.2 7.4 3.8 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others A2L_zn_ribbon PF08792.5 KEG12042.1 - 1.8 8.0 4.7 0.89 9.0 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain Nudix_N_2 PF14803.1 KEG12042.1 - 2.1 8.1 5.2 4.4 7.0 0.4 2.5 2 0 0 2 2 2 0 Nudix N-terminal AMP-binding PF00501.23 KEG12048.1 - 2e-84 283.4 0.7 5.2e-68 229.3 0.0 2.0 1 1 1 2 2 2 2 AMP-binding enzyme OrfB_Zn_ribbon PF07282.6 KEG12049.1 - 0.076 12.6 2.1 0.19 11.4 1.5 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain XRN_N PF03159.13 KEG12050.1 - 9.8e-43 146.2 0.0 6.4e-23 81.3 0.0 2.2 1 1 1 2 2 2 2 XRN 5'-3' exonuclease N-terminus DUF1192 PF06698.6 KEG12051.1 - 0.14 11.9 3.5 0.48 10.2 2.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) GFO_IDH_MocA PF01408.17 KEG12052.1 - 2.2e-15 57.2 0.0 5.7e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Rossmann-like PF10727.4 KEG12052.1 - 0.00019 21.1 0.1 0.00051 19.7 0.1 1.8 1 0 0 1 1 1 1 Rossmann-like domain GFO_IDH_MocA PF01408.17 KEG12053.1 - 1.3e-10 41.7 0.0 2.5e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold efb-c PF12199.3 KEG12055.1 - 0.14 12.0 0.1 0.28 11.0 0.1 1.4 1 0 0 1 1 1 0 Extracellular fibrinogen binding protein C terminal PBP1_TM PF14812.1 KEG12055.1 - 0.92 9.8 5.6 1.9 8.8 3.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WW PF00397.21 KEG12056.1 - 6.8e-25 86.5 21.3 5.8e-09 35.6 0.8 3.5 3 0 0 3 3 3 3 WW domain DUF4585 PF15232.1 KEG12056.1 - 0.024 14.4 0.0 3.7 7.4 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4585) TAP42 PF04177.7 KEG12058.1 - 5.3e-32 111.1 3.3 7.5e-32 110.6 2.3 1.1 1 0 0 1 1 1 1 TAP42-like family ATP_bind_1 PF03029.12 KEG12060.1 - 3.6e-61 206.7 0.0 4.1e-61 206.5 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 KEG12060.1 - 2e-06 28.6 0.0 4.5e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 KEG12060.1 - 0.00016 21.5 0.0 0.00051 19.9 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_19 PF13245.1 KEG12060.1 - 0.00018 21.1 0.0 0.00037 20.1 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KEG12060.1 - 0.00024 21.2 0.0 0.00044 20.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEG12060.1 - 0.00025 21.0 0.0 0.0011 18.9 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 KEG12060.1 - 0.00093 18.7 0.0 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain AAA_18 PF13238.1 KEG12060.1 - 0.0016 18.7 0.0 0.0039 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 KEG12060.1 - 0.0018 18.0 0.1 0.0034 17.0 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 KEG12060.1 - 0.0024 17.4 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KEG12060.1 - 0.0043 17.3 0.0 0.0093 16.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SRP54 PF00448.17 KEG12060.1 - 0.0055 16.1 0.0 0.013 15.0 0.0 1.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain CbiA PF01656.18 KEG12060.1 - 0.0063 15.9 0.0 0.018 14.4 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_14 PF13173.1 KEG12060.1 - 0.0066 16.3 0.0 0.015 15.1 0.0 1.6 2 0 0 2 2 1 1 AAA domain PhoH PF02562.11 KEG12060.1 - 0.0072 15.5 0.0 0.016 14.4 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein KAP_NTPase PF07693.9 KEG12060.1 - 0.0075 15.3 0.0 0.0082 15.1 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain AAA_33 PF13671.1 KEG12060.1 - 0.0094 15.8 0.0 0.027 14.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KEG12060.1 - 0.012 15.0 0.1 0.028 13.8 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.1 KEG12060.1 - 0.012 15.1 0.1 0.078 12.5 0.0 2.1 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 KEG12060.1 - 0.017 14.5 0.0 0.5 9.8 0.0 2.3 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 KEG12060.1 - 0.022 14.9 0.0 0.11 12.7 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_29 PF13555.1 KEG12060.1 - 0.029 13.8 0.1 0.057 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.7 KEG12060.1 - 0.038 13.6 0.1 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA PF00004.24 KEG12060.1 - 0.041 14.0 0.0 0.092 12.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ArgK PF03308.11 KEG12060.1 - 0.054 12.2 0.0 0.11 11.2 0.0 1.5 1 0 0 1 1 1 0 ArgK protein AAA_28 PF13521.1 KEG12060.1 - 0.057 13.3 0.1 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 KEG12060.1 - 0.058 12.2 0.0 0.086 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.9 KEG12060.1 - 0.072 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Thymidylate_kin PF02223.12 KEG12060.1 - 0.083 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Thymidylate kinase Viral_helicase1 PF01443.13 KEG12060.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.12 KEG12060.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Surp PF01805.15 KEG12061.1 - 1.2e-10 40.8 7.0 1.2e-07 31.3 0.4 2.3 2 0 0 2 2 2 2 Surp module Dicty_REP PF05086.7 KEG12061.1 - 6.5 4.3 11.3 0.42 8.3 0.1 2.1 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein DNA_pol_E_B PF04042.11 KEG12062.1 - 1.1e-30 106.4 0.1 5e-30 104.3 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Ras PF00071.17 KEG12063.1 - 4.7e-50 169.1 0.0 5.7e-50 168.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEG12063.1 - 1.6e-16 60.8 0.0 3e-16 59.9 0.0 1.5 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 KEG12063.1 - 2.2e-10 40.0 0.0 3.2e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KEG12063.1 - 0.00036 19.7 0.0 0.00046 19.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RNA_helicase PF00910.17 KEG12063.1 - 0.0011 19.1 0.2 0.007 16.5 0.1 2.1 1 1 0 1 1 1 1 RNA helicase G-alpha PF00503.15 KEG12063.1 - 0.017 13.8 1.0 0.66 8.6 0.1 2.8 2 1 1 3 3 3 0 G-protein alpha subunit AAA_33 PF13671.1 KEG12063.1 - 0.042 13.7 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 KEG12063.1 - 0.044 13.2 0.4 0.43 9.9 0.3 2.1 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KEG12063.1 - 0.044 13.9 0.2 0.35 11.0 0.0 2.3 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 KEG12063.1 - 0.076 12.4 0.1 3.3 7.1 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.7 KEG12063.1 - 0.086 12.1 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein ATP_bind_1 PF03029.12 KEG12063.1 - 0.14 11.7 0.2 13 5.1 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.13 KEG12063.1 - 0.14 11.1 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 Septin Cluap1 PF10234.4 KEG12064.1 - 1.1e-100 336.2 8.0 1.7e-100 335.6 5.5 1.3 1 0 0 1 1 1 1 Clusterin-associated protein-1 SseC PF04888.7 KEG12064.1 - 0.0034 16.7 5.6 0.005 16.2 3.9 1.2 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family Prominin PF05478.6 KEG12064.1 - 0.022 12.3 2.2 0.029 11.9 1.5 1.1 1 0 0 1 1 1 0 Prominin MutS_II PF05188.12 KEG12064.1 - 0.091 12.8 1.8 0.2 11.7 1.2 1.6 1 0 0 1 1 1 0 MutS domain II SPT16 PF08644.6 KEG12064.1 - 0.35 10.6 3.5 0.41 10.4 1.5 1.7 1 1 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) COG2 PF06148.6 KEG12064.1 - 0.94 9.3 8.8 0.25 11.2 2.8 2.3 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DivIC PF04977.10 KEG12064.1 - 2.8 7.5 7.2 1.1 8.8 0.9 2.6 2 0 0 2 2 2 0 Septum formation initiator RNase_T PF00929.19 KEG12065.1 - 3e-09 37.3 0.0 5.1e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DUF3317 PF11779.3 KEG12067.1 - 0.0086 15.4 4.3 0.021 14.2 3.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3317) DUF1295 PF06966.7 KEG12068.1 - 3.3e-10 39.6 0.8 4.7e-10 39.1 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 KEG12068.1 - 2.7e-07 30.4 2.5 4.2e-07 29.8 1.7 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 KEG12068.1 - 3.6e-05 23.7 0.8 7.6e-05 22.7 0.4 1.7 1 1 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.9 KEG12068.1 - 0.00019 21.5 0.0 0.0004 20.5 0.0 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.12 KEG12068.1 - 0.0034 16.0 0.8 0.0053 15.3 0.1 1.4 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Na_Ca_ex PF01699.19 KEG12068.1 - 0.059 12.9 2.2 0.094 12.3 0.4 2.0 2 0 0 2 2 2 0 Sodium/calcium exchanger protein RF-1 PF00472.15 KEG12069.1 - 3.1e-30 104.3 0.0 6.3e-30 103.3 0.0 1.6 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 KEG12069.1 - 1.8e-13 50.1 0.1 3.7e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 PCRF domain DUF1126 PF06565.7 KEG12070.1 - 1.2e-32 111.0 1.7 2.5e-10 39.6 0.1 3.6 3 0 0 3 3 3 3 Repeat of unknown function (DUF1126) Cyclin_N PF00134.18 KEG12071.1 - 9.4e-36 122.1 0.0 1.5e-35 121.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KEG12071.1 - 2.3e-16 59.7 0.0 4.6e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain NfI_DNAbd_pre-N PF10524.4 KEG12071.1 - 0.0081 15.7 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Nuclear factor I protein pre-N-terminus CoA_binding_2 PF13380.1 KEG12073.1 - 0.09 12.9 0.2 0.17 12.0 0.1 1.5 1 1 0 1 1 1 0 CoA binding domain Fer2_2 PF01799.15 KEG12075.1 - 0.018 14.9 0.1 0.026 14.4 0.1 1.3 1 0 0 1 1 1 0 [2Fe-2S] binding domain RINGv PF12906.2 KEG12075.1 - 0.018 15.0 0.4 0.039 14.0 0.3 1.5 1 0 0 1 1 1 0 RING-variant domain IMS PF00817.15 KEG12076.1 - 2e-39 134.7 0.0 3.3e-39 134.0 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KEG12076.1 - 6.6e-07 29.3 0.0 1.4e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain PGM_PMM_I PF02878.11 KEG12077.1 - 6.1e-33 113.2 0.1 9.8e-33 112.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 KEG12077.1 - 1.6e-24 86.1 0.0 4.3e-24 84.7 0.0 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 KEG12077.1 - 2.5e-10 40.2 0.0 6.7e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.11 KEG12077.1 - 6.3e-10 39.3 0.0 2e-09 37.6 0.0 1.9 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II RPA PF10134.4 KEG12078.1 - 0.094 11.9 0.0 2.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Replication initiator protein A ParA PF10609.4 KEG12079.1 - 1.6e-31 107.9 0.1 3.6e-31 106.8 0.0 1.6 2 0 0 2 2 1 1 ParA/MinD ATPase like CbiA PF01656.18 KEG12079.1 - 2e-17 63.2 0.0 2.7e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KEG12079.1 - 9.3e-07 28.9 0.0 3e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain MipZ PF09140.6 KEG12079.1 - 1.5e-05 24.2 0.0 2.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ ArgK PF03308.11 KEG12079.1 - 0.00014 20.7 0.3 0.00022 20.1 0.2 1.2 1 0 0 1 1 1 1 ArgK protein MobB PF03205.9 KEG12079.1 - 0.00043 19.9 0.0 0.00074 19.2 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 KEG12079.1 - 0.00087 20.0 0.0 0.0015 19.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 KEG12079.1 - 0.00088 18.3 0.8 0.0015 17.6 0.5 1.3 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_16 PF13191.1 KEG12079.1 - 0.0015 18.5 0.1 0.0025 17.8 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 KEG12079.1 - 0.002 17.0 0.2 0.0031 16.4 0.2 1.2 1 0 0 1 1 1 1 NB-ARC domain DUF258 PF03193.11 KEG12079.1 - 0.0021 17.2 0.1 0.0041 16.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 KEG12079.1 - 0.0076 15.7 0.4 0.011 15.1 0.3 1.2 1 0 0 1 1 1 1 AAA-like domain AAA_25 PF13481.1 KEG12079.1 - 0.012 15.0 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 KEG12079.1 - 0.013 15.0 0.1 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 KEG12079.1 - 0.019 15.2 0.1 0.032 14.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain DUF1610 PF07754.6 KEG12079.1 - 0.032 14.3 0.8 0.17 12.0 0.6 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) NACHT PF05729.7 KEG12079.1 - 0.046 13.3 0.2 0.073 12.7 0.2 1.3 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.1 KEG12079.1 - 0.056 12.9 0.3 0.12 11.9 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.10 KEG12079.1 - 0.059 13.0 0.4 0.097 12.3 0.3 1.3 1 0 0 1 1 1 0 NTPase TF_Zn_Ribbon PF08271.7 KEG12079.1 - 0.065 12.5 0.1 0.16 11.2 0.1 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding SMC_N PF02463.14 KEG12079.1 - 0.065 12.4 0.4 0.12 11.6 0.3 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Zn_Tnp_IS1595 PF12760.2 KEG12079.1 - 0.081 12.7 0.1 0.34 10.7 0.0 2.0 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Fer4_NifH PF00142.13 KEG12079.1 - 0.084 12.0 0.1 0.21 10.7 0.1 1.6 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 KEG12079.1 - 0.098 12.0 0.6 0.14 11.5 0.1 1.4 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.1 KEG12079.1 - 0.1 12.7 0.3 0.25 11.4 0.2 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 KEG12079.1 - 0.22 10.1 0.1 0.33 9.5 0.1 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Hist_deacetyl PF00850.14 KEG12080.1 - 2.8e-72 243.6 0.1 3.5e-72 243.3 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain PB1 PF00564.19 KEG12081.1 - 0.028 14.0 0.0 0.064 12.9 0.0 1.5 2 0 0 2 2 2 0 PB1 domain EF-hand_7 PF13499.1 KEG12082.1 - 1.1e-08 35.1 0.1 8.8e-06 25.7 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KEG12082.1 - 2.2e-08 33.2 0.1 0.00034 20.2 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 KEG12082.1 - 1.6e-07 30.1 0.0 7.3e-05 21.8 0.0 2.8 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 KEG12082.1 - 2.4e-06 27.0 0.1 0.00023 20.7 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_9 PF14658.1 KEG12082.1 - 0.0046 16.8 0.0 1.6 8.7 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain Herpes_LMP1 PF05297.6 KEG12083.1 - 0.98 8.2 3.7 1.1 8.1 2.6 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) YGGT PF02325.12 KEG12083.1 - 3 7.8 7.3 0.69 9.8 1.6 2.0 2 0 0 2 2 2 0 YGGT family Tetraspannin PF00335.15 KEG12083.1 - 4.7 6.4 9.8 7.1 5.8 1.3 2.1 1 1 0 2 2 2 0 Tetraspanin family zf-DHHC PF01529.15 KEG12083.1 - 7 6.0 6.5 9.3 5.6 4.5 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase Abi PF02517.11 KEG12083.1 - 9.6 6.4 7.3 83 3.4 5.1 2.1 1 1 0 1 1 1 0 CAAX protease self-immunity ABC_tran PF00005.22 KEG12084.1 - 6.4e-37 126.9 0.0 1.4e-17 64.2 0.0 2.6 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KEG12084.1 - 3.7e-15 56.6 1.0 2.4e-05 24.4 0.3 4.4 2 2 0 3 3 3 2 AAA domain SMC_N PF02463.14 KEG12084.1 - 7.7e-12 44.9 1.4 0.0097 15.1 0.0 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain RLI PF04068.10 KEG12084.1 - 7.9e-10 38.1 3.3 2e-09 36.8 2.3 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Fer4 PF00037.22 KEG12084.1 - 2.2e-09 36.5 2.0 2.2e-09 36.5 1.4 2.3 3 0 0 3 3 1 1 4Fe-4S binding domain AAA_15 PF13175.1 KEG12084.1 - 9.5e-08 31.4 0.0 0.1 11.6 0.0 4.0 4 0 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 KEG12084.1 - 1.9e-06 28.0 0.7 0.00034 20.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain Fer4_6 PF12837.2 KEG12084.1 - 2.3e-06 27.2 0.9 2.3e-06 27.2 0.7 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_29 PF13555.1 KEG12084.1 - 4.1e-06 26.2 0.1 0.011 15.2 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain Fer4_7 PF12838.2 KEG12084.1 - 9.7e-06 25.8 7.8 7.9e-05 22.9 0.1 2.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_23 PF13476.1 KEG12084.1 - 1.6e-05 25.2 0.1 0.0087 16.3 0.1 2.4 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KEG12084.1 - 4.3e-05 23.9 0.0 0.0068 16.9 0.0 2.8 3 0 0 3 3 2 1 Miro-like protein DUF258 PF03193.11 KEG12084.1 - 7.7e-05 21.9 0.0 0.046 12.9 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KEG12084.1 - 9.9e-05 22.3 1.4 0.014 15.4 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 KEG12084.1 - 0.00032 20.9 0.0 0.038 14.1 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KEG12084.1 - 0.00034 20.3 1.0 0.0069 16.0 0.0 2.4 2 0 0 2 2 2 1 NACHT domain Fer4_21 PF14697.1 KEG12084.1 - 0.00035 20.3 15.8 0.00086 19.1 11.0 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 KEG12084.1 - 0.00044 19.9 2.1 0.00044 19.9 1.5 2.7 2 0 0 2 2 1 1 4Fe-4S binding domain VirE PF05272.6 KEG12084.1 - 0.00044 19.7 0.1 0.14 11.5 0.0 2.6 2 0 0 2 2 2 1 Virulence-associated protein E AAA_28 PF13521.1 KEG12084.1 - 0.0005 20.0 0.0 0.34 10.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain Fer4_10 PF13237.1 KEG12084.1 - 0.00063 19.4 1.4 0.00063 19.4 0.9 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain AAA_33 PF13671.1 KEG12084.1 - 0.00065 19.5 0.0 0.31 10.9 0.0 3.1 3 0 0 3 3 3 1 AAA domain Fer4_9 PF13187.1 KEG12084.1 - 0.0012 19.0 12.6 0.004 17.3 8.8 2.0 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_13 PF13166.1 KEG12084.1 - 0.0013 17.3 0.1 0.029 12.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KEG12084.1 - 0.0018 18.1 0.1 0.27 11.1 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.1 KEG12084.1 - 0.0021 17.4 0.0 0.9 8.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain Fer4_3 PF12798.2 KEG12084.1 - 0.0033 17.8 5.2 0.0033 17.8 3.6 2.8 2 0 0 2 2 1 1 4Fe-4S binding domain UPF0079 PF02367.12 KEG12084.1 - 0.0046 16.5 0.1 0.045 13.3 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 KEG12084.1 - 0.0049 17.0 0.0 0.96 9.6 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Fer4_16 PF13484.1 KEG12084.1 - 0.0059 17.3 7.4 0.006 17.2 0.1 2.5 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain AAA_17 PF13207.1 KEG12084.1 - 0.0061 17.3 0.9 4.9 8.0 0.1 3.3 2 2 0 2 2 2 0 AAA domain Fer4_4 PF12800.2 KEG12084.1 - 0.008 16.4 2.0 0.008 16.4 1.4 2.6 2 0 0 2 2 1 1 4Fe-4S binding domain SRP54 PF00448.17 KEG12084.1 - 0.012 15.0 1.3 0.66 9.3 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Rad17 PF03215.10 KEG12084.1 - 0.02 13.6 0.0 2 6.9 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein MobB PF03205.9 KEG12084.1 - 0.021 14.5 0.5 2.1 8.0 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 KEG12084.1 - 0.036 14.3 0.0 15 5.9 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.9 KEG12084.1 - 0.037 13.7 0.3 2.2 7.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 KEG12084.1 - 0.047 13.2 0.0 3.7 7.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 KEG12084.1 - 0.054 13.4 0.3 5.4 7.0 0.0 2.7 2 2 0 2 2 2 0 50S ribosome-binding GTPase Arch_ATPase PF01637.13 KEG12084.1 - 0.085 12.5 0.0 0.27 10.8 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase PduV-EutP PF10662.4 KEG12084.1 - 0.091 12.2 2.9 0.23 10.9 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation SbcCD_C PF13558.1 KEG12084.1 - 0.095 12.6 0.1 20 5.1 0.0 3.0 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Sigma54_activ_2 PF14532.1 KEG12084.1 - 0.099 12.6 0.0 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.1 KEG12084.1 - 0.16 11.7 1.1 38 4.1 0.0 3.2 3 0 0 3 3 3 0 Part of AAA domain NB-ARC PF00931.17 KEG12084.1 - 0.21 10.4 0.5 6 5.6 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Fer4_8 PF13183.1 KEG12084.1 - 4.3 7.4 13.8 16 5.6 9.7 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_17 PF13534.1 KEG12084.1 - 4.5 7.6 15.3 64 4.0 10.7 2.5 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_15 PF13459.1 KEG12084.1 - 6.4 7.4 9.3 0.1 13.2 0.6 2.4 2 0 0 2 2 1 0 4Fe-4S single cluster domain DSPc PF00782.15 KEG12085.1 - 3.8e-21 75.0 0.0 5.7e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Leu_Phe_trans PF03588.9 KEG12087.1 - 2.4e-07 30.0 0.1 1.3e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 Leucyl/phenylalanyl-tRNA protein transferase Alveol-reg_P311 PF11092.3 KEG12087.1 - 0.1 12.5 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Neuronal protein 3.1 (p311) Ribosomal_L36e PF01158.13 KEG12088.1 - 7.1e-34 115.7 6.1 8.9e-34 115.3 4.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Pkinase PF00069.20 KEG12090.1 - 7.2e-58 195.7 0.0 9.1e-58 195.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG12090.1 - 2e-26 92.6 0.0 4e-26 91.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEG12090.1 - 0.00013 21.8 0.3 0.089 12.5 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family HAP1_N PF04849.8 KEG12091.1 - 0.0044 16.0 15.9 0.038 12.9 0.4 3.7 2 1 0 3 3 3 2 HAP1 N-terminal conserved region CCDC155 PF14662.1 KEG12091.1 - 0.01 15.4 15.0 0.13 11.8 6.2 3.1 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 Leu_zip PF15294.1 KEG12091.1 - 0.026 13.6 13.7 0.079 12.0 3.3 2.9 3 0 0 3 3 3 0 Leucine zipper TMF_DNA_bd PF12329.3 KEG12091.1 - 0.15 11.8 0.1 0.15 11.8 0.1 4.3 4 1 0 4 4 4 0 TATA element modulatory factor 1 DNA binding WD40_alt PF14077.1 KEG12091.1 - 0.24 11.0 0.1 0.24 11.0 0.0 3.4 4 0 0 4 4 4 0 Alternative WD40 repeat motif DASH_Dad2 PF08654.5 KEG12091.1 - 0.28 11.1 3.3 1.2 9.2 0.0 3.4 3 0 0 3 3 3 0 DASH complex subunit Dad2 DUF972 PF06156.8 KEG12091.1 - 0.29 11.4 17.1 3.3 8.0 0.5 4.7 3 2 1 4 4 4 0 Protein of unknown function (DUF972) TSC22 PF01166.13 KEG12091.1 - 0.37 10.7 4.5 8.9 6.3 0.8 3.4 2 1 0 2 2 2 0 TSC-22/dip/bun family DivIC PF04977.10 KEG12091.1 - 5.3 6.6 14.5 9.6 5.7 0.2 4.7 4 1 0 5 5 5 0 Septum formation initiator GrpE PF01025.14 KEG12091.1 - 6.4 6.2 15.9 0.55 9.7 4.3 2.9 3 0 0 3 3 3 0 GrpE Spc7 PF08317.6 KEG12091.1 - 8.1 4.9 15.3 1.2 7.6 3.1 2.7 3 0 0 3 3 3 0 Spc7 kinetochore protein DUF2462 PF09495.5 KEG12092.1 - 8.2 7.2 21.0 0.093 13.4 6.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2462) Dynein_heavy PF03028.10 KEG12093.1 - 2.1e-18 65.7 0.0 2.3e-18 65.6 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor Dynein_heavy PF03028.10 KEG12094.1 - 1.5e-185 618.3 0.2 8.1e-185 615.8 0.0 2.2 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 KEG12094.1 - 1.7e-128 428.6 1.3 1.7e-128 428.6 0.9 3.5 4 0 0 4 4 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 KEG12094.1 - 1.1e-86 290.1 0.8 7.4e-86 287.4 0.1 2.5 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 KEG12094.1 - 1.4e-59 201.3 0.1 4.9e-59 199.4 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 KEG12094.1 - 5.5e-55 185.6 0.6 2.3e-54 183.6 0.1 2.2 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 MT PF12777.2 KEG12094.1 - 9.3e-52 175.8 0.8 2.2e-51 174.6 0.6 1.7 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.2 KEG12094.1 - 7.3e-34 117.0 0.0 2.4e-33 115.4 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_5 PF07728.9 KEG12094.1 - 1.4e-12 47.5 0.8 0.00063 19.4 0.0 7.0 6 1 0 6 6 6 2 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 KEG12094.1 - 7.6e-07 28.9 1.2 0.48 9.9 0.0 3.6 3 0 0 3 3 3 3 AAA domain AAA_22 PF13401.1 KEG12094.1 - 1e-06 28.9 9.2 0.065 13.3 0.0 7.0 9 0 0 9 9 6 1 AAA domain AAA PF00004.24 KEG12094.1 - 3.4e-06 27.2 0.7 1.2 9.3 0.0 4.5 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KEG12094.1 - 3.6e-06 27.1 0.2 0.046 13.9 0.0 3.8 3 0 0 3 3 3 2 RNA helicase T2SE PF00437.15 KEG12094.1 - 4.1e-06 25.8 0.1 0.0024 16.8 0.0 3.8 4 0 0 4 4 4 1 Type II/IV secretion system protein AAA_19 PF13245.1 KEG12094.1 - 9.3e-06 25.3 2.8 0.92 9.3 0.1 4.2 4 0 0 4 4 4 2 Part of AAA domain AAA_17 PF13207.1 KEG12094.1 - 3.9e-05 24.4 0.4 0.057 14.2 0.0 4.9 4 0 0 4 4 2 1 AAA domain Mg_chelatase PF01078.16 KEG12094.1 - 0.00011 21.4 0.6 0.057 12.5 0.0 4.6 5 0 0 5 5 5 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KEG12094.1 - 0.0009 18.7 2.7 1.6 8.0 0.0 4.5 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_25 PF13481.1 KEG12094.1 - 0.0024 17.2 4.2 0.31 10.4 0.0 3.9 3 0 0 3 3 3 1 AAA domain DEAD PF00270.24 KEG12094.1 - 0.005 16.3 0.2 1.5 8.3 0.0 3.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.10 KEG12094.1 - 0.0051 16.6 0.6 10 5.8 0.0 3.8 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit NACHT PF05729.7 KEG12094.1 - 0.025 14.2 1.5 6.8 6.3 0.0 3.7 3 0 0 3 3 3 0 NACHT domain AAA_33 PF13671.1 KEG12094.1 - 0.025 14.4 4.4 3.6 7.4 0.0 4.7 4 0 0 4 4 4 0 AAA domain PhoH PF02562.11 KEG12094.1 - 0.026 13.7 6.6 0.43 9.7 0.0 4.0 4 0 0 4 4 4 0 PhoH-like protein AAA_18 PF13238.1 KEG12094.1 - 0.034 14.4 0.0 0.034 14.4 0.0 4.7 6 0 0 6 6 3 0 AAA domain DUF853 PF05872.7 KEG12094.1 - 0.09 11.1 2.8 17 3.6 0.1 3.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) DUF390 PF04094.9 KEG12094.1 - 0.22 9.5 6.1 0.4 8.6 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF390) AAA_16 PF13191.1 KEG12094.1 - 0.23 11.4 10.8 6.7 6.6 0.0 5.8 6 1 0 7 7 6 0 AAA ATPase domain SRP54 PF00448.17 KEG12094.1 - 1.9 7.8 5.1 26 4.1 0.1 3.4 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain DUF948 PF06103.6 KEG12094.1 - 8.9 6.2 10.8 1.8 8.4 0.1 4.7 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Pkinase PF00069.20 KEG12095.1 - 3e-54 183.9 0.0 9.2e-54 182.3 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG12095.1 - 2.5e-37 128.3 0.0 7.8e-35 120.1 0.0 3.2 3 0 0 3 3 3 1 Protein tyrosine kinase DUF1902 PF08972.6 KEG12095.1 - 0.0048 16.4 0.1 0.011 15.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1902) RIO1 PF01163.17 KEG12095.1 - 0.11 11.8 0.1 0.87 8.9 0.0 2.2 2 0 0 2 2 2 0 RIO1 family ER_lumen_recept PF00810.13 KEG12096.1 - 5.2e-54 182.7 8.9 8.7e-54 182.0 6.1 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor Peptidase_M20 PF01546.23 KEG12097.1 - 2.2e-21 76.2 0.0 3.2e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KEG12097.1 - 1.1e-09 38.0 0.0 1.8e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain adh_short PF00106.20 KEG12099.1 - 2.1e-19 70.0 0.0 3e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEG12099.1 - 6e-10 39.2 0.0 8.8e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEG12099.1 - 4.8e-06 26.3 0.0 7.7e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KEG12099.1 - 0.011 15.8 0.0 0.078 12.9 0.0 2.1 2 0 0 2 2 2 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KEG12099.1 - 0.021 14.6 0.1 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KEG12099.1 - 0.044 13.2 0.0 0.2 11.0 0.0 1.9 1 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family WD40 PF00400.27 KEG12100.1 - 0.00051 19.8 0.0 17 5.4 0.0 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat Ribul_P_3_epim PF00834.14 KEG12102.1 - 1.1e-66 223.8 0.1 1.3e-66 223.5 0.1 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family Radical_SAM PF04055.16 KEG12102.1 - 0.003 17.7 0.0 0.036 14.2 0.0 2.0 1 1 1 2 2 2 1 Radical SAM superfamily OMPdecase PF00215.19 KEG12102.1 - 0.018 14.4 0.2 0.041 13.2 0.1 1.7 2 1 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family QRPTase_C PF01729.14 KEG12102.1 - 0.019 14.5 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain PcrB PF01884.12 KEG12102.1 - 0.023 13.9 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 PcrB family DUF1932 PF09130.6 KEG12102.1 - 0.063 13.0 0.1 0.19 11.4 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1932) PRA1 PF03208.14 KEG12104.1 - 2.5e-38 130.8 9.8 3e-38 130.5 6.8 1.0 1 0 0 1 1 1 1 PRA1 family protein DUF2269 PF10027.4 KEG12104.1 - 0.031 14.0 4.9 0.1 12.3 4.0 1.5 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) PRA1 PF03208.14 KEG12106.1 - 3.1e-19 68.8 0.6 4.9e-19 68.1 0.4 1.3 1 0 0 1 1 1 1 PRA1 family protein DUF3112 PF11309.3 KEG12106.1 - 0.02 14.6 1.1 0.056 13.2 0.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3112) DUF3166 PF11365.3 KEG12108.1 - 0.11 12.9 0.0 1.3 9.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) ubiquitin PF00240.18 KEG12110.1 - 2.6e-10 39.5 0.0 4.1e-05 22.9 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin family SAPS PF04499.10 KEG12112.1 - 2.5 6.6 10.5 2.7 6.5 3.7 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Mitoc_L55 PF09776.4 KEG12116.1 - 0.15 11.6 0.0 0.46 10.0 0.0 1.8 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L55 NIF PF03031.13 KEG12117.1 - 2.6e-26 92.1 0.0 1.7e-21 76.5 0.0 2.3 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase Cyclin PF08613.6 KEG12118.1 - 1.7e-34 119.3 0.0 4e-34 118.1 0.0 1.7 1 0 0 1 1 1 1 Cyclin zf-MIZ PF02891.15 KEG12120.1 - 1.1e-18 66.5 10.2 2.3e-18 65.4 7.1 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-C3HC4_2 PF13923.1 KEG12120.1 - 9 6.4 13.1 16 5.5 8.3 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 KEG12120.1 - 9.8 5.7 7.8 15 5.2 4.5 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Pkinase PF00069.20 KEG12121.1 - 1.5e-69 234.0 0.0 1.8e-69 233.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG12121.1 - 9.9e-34 116.5 0.0 1.2e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG12121.1 - 3.4e-06 26.2 0.0 4.3e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEG12121.1 - 0.083 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family PROCN PF08083.6 KEG12122.1 - 8.9e-179 594.2 7.7 8.9e-179 594.2 5.3 1.5 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 KEG12122.1 - 6.4e-91 303.7 0.0 9.9e-91 303.1 0.0 1.3 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 KEG12122.1 - 2.3e-68 228.5 0.0 5.6e-68 227.3 0.0 1.7 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 KEG12122.1 - 4.9e-62 208.0 0.0 1.1e-61 206.9 0.0 1.6 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 KEG12122.1 - 7.3e-54 181.0 2.1 1.1e-53 180.5 0.0 2.3 2 0 0 2 2 2 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 KEG12122.1 - 1.1e-35 121.4 0.0 2.4e-35 120.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 KEG12122.1 - 2.1e-34 117.9 0.0 4.2e-34 116.9 0.0 1.6 1 0 0 1 1 1 1 PROCT (NUC072) domain YqgB PF11036.3 KEG12123.1 - 0.47 10.0 2.8 0.34 10.4 0.4 1.9 2 0 0 2 2 2 0 Virulence promoting factor INCENP_N PF12178.3 KEG12124.1 - 2.8e-17 61.9 0.1 5e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 Chromosome passenger complex (CPC) protein INCENP N terminal UNC-50 PF05216.8 KEG12125.1 - 2.8e-78 262.3 14.0 3.3e-78 262.0 9.7 1.0 1 0 0 1 1 1 1 UNC-50 family DUF4191 PF13829.1 KEG12125.1 - 5.9 5.9 7.0 0.3 10.1 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DUF1003 PF06210.6 KEG12125.1 - 6.9 6.6 6.1 30 4.5 0.1 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1003) SHIPPO-rpt PF07004.7 KEG12126.1 - 1.1e-13 51.2 38.3 0.019 15.8 0.1 9.9 10 0 0 10 10 10 8 Sperm-tail PG-rich repeat KNOX1 PF03790.8 KEG12127.1 - 0.48 9.7 1.7 0.87 8.9 0.2 2.2 2 0 0 2 2 2 0 KNOX1 domain HCNGP PF07818.8 KEG12128.1 - 0.025 14.5 0.0 0.038 14.0 0.0 1.3 1 0 0 1 1 1 0 HCNGP-like protein TFIID-18kDa PF02269.11 KEG12128.1 - 0.039 13.7 0.2 0.084 12.7 0.2 1.6 1 1 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Y1_Tnp PF01797.11 KEG12128.1 - 0.047 13.5 0.1 0.98 9.2 0.0 2.1 2 0 0 2 2 2 0 Transposase IS200 like DUF334 PF03904.8 KEG12128.1 - 0.31 10.3 3.4 4.3 6.5 2.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF334) Mito_carr PF00153.22 KEG12129.1 - 2.4e-19 68.8 4.9 7.6e-11 41.5 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2938 PF11158.3 KEG12129.1 - 0.052 12.8 0.1 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2938) BTV_NS2 PF04514.7 KEG12131.1 - 0.016 14.1 11.2 0.019 13.9 7.8 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Seryl_tRNA_N PF02403.17 KEG12131.1 - 0.11 12.4 9.7 0.19 11.7 6.7 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF1168 PF06658.7 KEG12131.1 - 0.17 11.3 19.4 0.2 11.1 13.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) GAGA_bind PF06217.7 KEG12131.1 - 1.3 8.9 6.5 1.4 8.8 4.5 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family TT_ORF2 PF02957.10 KEG12131.1 - 5.1 7.8 9.9 4.2 8.0 4.6 2.0 1 1 1 2 2 2 0 TT viral ORF2 EVC2_like PF12297.3 KEG12132.1 - 0.14 10.7 4.7 0.2 10.2 0.5 2.5 3 0 0 3 3 3 0 Ellis van Creveld protein 2 like protein Spermine_synth PF01564.12 KEG12133.1 - 2e-71 239.7 0.0 2.6e-71 239.4 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 KEG12133.1 - 2.9e-05 24.0 0.0 5.8e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEG12133.1 - 0.0036 17.7 0.0 0.012 16.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEG12133.1 - 0.011 16.2 0.0 0.04 14.3 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KEG12133.1 - 0.042 14.4 0.0 0.073 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_30 PF05430.6 KEG12133.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase DENN PF02141.16 KEG12134.1 - 7e-11 42.1 0.3 1.2e-10 41.3 0.2 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain Avl9 PF09794.4 KEG12134.1 - 0.21 10.0 0.1 3 6.2 0.1 2.2 1 1 1 2 2 2 0 Transport protein Avl9 Y_phosphatase2 PF03162.8 KEG12136.1 - 4.8e-53 178.9 0.0 6.5e-53 178.4 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 KEG12136.1 - 1.6e-09 38.1 0.2 1.2e-08 35.3 0.0 2.2 2 1 1 3 3 3 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 KEG12136.1 - 0.00023 20.5 0.0 0.00034 20.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KEG12136.1 - 0.0051 16.4 0.0 0.0078 15.7 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 KEG12136.1 - 0.021 14.8 0.5 0.035 14.1 0.0 1.6 2 0 0 2 2 2 0 Inositol hexakisphosphate Myotub-related PF06602.9 KEG12136.1 - 0.025 13.3 0.0 0.043 12.5 0.0 1.3 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain YadA_anchor PF03895.10 KEG12136.1 - 0.53 10.3 6.8 0.6 10.1 4.1 1.5 1 1 0 1 1 1 0 YadA-like C-terminal region SSP160 PF06933.6 KEG12136.1 - 0.72 7.7 13.4 0.95 7.3 9.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TPR_19 PF14559.1 KEG12138.1 - 2.2e-39 133.6 55.8 1.8e-06 28.1 0.0 16.1 11 5 3 15 15 15 10 Tetratricopeptide repeat TPR_11 PF13414.1 KEG12138.1 - 2.5e-38 129.5 57.9 1.2e-09 37.7 0.9 14.1 12 3 6 18 18 18 11 TPR repeat TPR_16 PF13432.1 KEG12138.1 - 1.9e-34 117.6 67.8 1.1e-05 25.9 2.1 16.6 13 5 6 20 20 20 10 Tetratricopeptide repeat TPR_2 PF07719.12 KEG12138.1 - 4.3e-30 101.1 59.2 0.00025 20.7 0.1 19.5 21 0 0 21 21 18 9 Tetratricopeptide repeat TPR_14 PF13428.1 KEG12138.1 - 8.5e-29 97.4 76.2 0.0014 19.0 0.1 22.1 15 8 11 26 26 23 9 Tetratricopeptide repeat TPR_1 PF00515.23 KEG12138.1 - 4.2e-21 73.6 44.2 8.1e-06 25.2 0.3 15.5 18 0 0 18 18 17 6 Tetratricopeptide repeat TPR_12 PF13424.1 KEG12138.1 - 1.1e-20 73.2 57.4 8.2e-06 25.6 0.6 13.2 10 3 3 14 14 13 7 Tetratricopeptide repeat TPR_8 PF13181.1 KEG12138.1 - 6.9e-18 63.0 28.4 0.00094 18.7 0.1 14.1 15 1 1 16 16 16 3 Tetratricopeptide repeat Apc3 PF12895.2 KEG12138.1 - 5.5e-14 52.0 43.5 0.0026 17.8 0.1 11.3 8 3 4 13 13 12 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 KEG12138.1 - 2.1e-11 43.0 26.6 1.6 9.1 0.0 13.6 15 0 0 15 15 15 3 Tetratricopeptide repeat TPR_7 PF13176.1 KEG12138.1 - 4.5e-11 41.6 45.7 0.0035 17.0 0.0 12.4 15 0 0 15 15 12 4 Tetratricopeptide repeat RPN7 PF10602.4 KEG12138.1 - 2.2e-07 30.4 11.8 0.0012 18.2 0.1 7.0 7 1 0 7 7 7 1 26S proteasome subunit RPN7 NARP1 PF12569.3 KEG12138.1 - 3.5e-07 29.3 15.0 6.3e-06 25.2 0.1 5.5 5 3 1 6 6 6 2 NMDA receptor-regulated protein 1 TPR_6 PF13174.1 KEG12138.1 - 2.3e-05 24.5 45.6 0.36 11.3 0.2 16.9 19 0 0 19 19 18 2 Tetratricopeptide repeat HemY_N PF07219.8 KEG12138.1 - 0.035 13.6 2.0 7.4 6.1 0.1 4.7 4 0 0 4 4 4 0 HemY protein N-terminus Apc5 PF12862.2 KEG12138.1 - 0.44 10.4 18.6 1.9 8.3 1.8 6.4 6 1 1 7 7 6 0 Anaphase-promoting complex subunit 5 MIT PF04212.13 KEG12138.1 - 1.2 9.0 21.8 7.9 6.4 0.1 7.3 6 1 1 7 7 6 0 MIT (microtubule interacting and transport) domain GPI2 PF06432.6 KEG12140.1 - 9.5e-80 267.9 11.4 1.1e-79 267.7 7.9 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF1440 PF07274.7 KEG12140.1 - 0.01 15.7 0.1 0.01 15.7 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1440) Flp_Fap PF04964.9 KEG12140.1 - 0.068 12.7 0.0 0.27 10.8 0.0 2.1 1 0 0 1 1 1 0 Flp/Fap pilin component Beach PF02138.13 KEG12141.1 - 1.3e-99 333.0 0.0 2.2e-99 332.3 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.27 KEG12141.1 - 8.3e-12 44.5 1.2 0.00076 19.2 0.0 3.9 3 0 0 3 3 3 3 WD domain, G-beta repeat Laminin_G_3 PF13385.1 KEG12141.1 - 5.6e-11 42.9 0.0 1.2e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.1 KEG12141.1 - 1e-10 41.4 0.0 2.2e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Herpes_UL87 PF03043.9 KEG12141.1 - 1.8 6.8 5.0 1.4 7.2 0.1 2.6 3 0 0 3 3 3 0 Herpesvirus UL87 family Sec34 PF04136.10 KEG12142.1 - 6.4e-13 48.6 0.2 6.4e-13 48.6 0.1 2.9 3 0 0 3 3 3 1 Sec34-like family Lactonase PF10282.4 KEG12144.1 - 0.0065 15.5 0.2 0.13 11.3 0.0 2.6 2 1 0 2 2 2 1 Lactonase, 7-bladed beta-propeller FAD_binding_8 PF08022.7 KEG12144.1 - 0.077 12.8 0.0 3.5 7.5 0.0 2.3 2 0 0 2 2 2 0 FAD-binding domain NHL PF01436.16 KEG12144.1 - 1.2 9.1 3.9 7.5 6.7 0.0 3.6 5 0 0 5 5 5 0 NHL repeat Amastin PF07344.6 KEG12145.1 - 2.7e-33 114.7 3.9 3.5e-33 114.4 2.7 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein PMP22_Claudin PF00822.15 KEG12145.1 - 0.0021 17.7 3.3 0.003 17.2 2.3 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family DUF1056 PF06341.6 KEG12145.1 - 0.14 12.2 0.3 0.14 12.2 0.2 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1056) Claudin_2 PF13903.1 KEG12145.1 - 0.39 10.3 9.6 0.03 14.0 1.8 2.0 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF4094 PF13334.1 KEG12145.1 - 3.9 7.9 5.1 7.5 7.0 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) GlcNAc PF11397.3 KEG12146.1 - 5.9e-114 380.7 0.0 6.9e-114 380.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) Amidase PF01425.16 KEG12147.1 - 8.2e-06 24.9 0.0 0.0081 15.0 0.0 2.5 2 0 0 2 2 2 2 Amidase BAF1_ABF1 PF04684.8 KEG12149.1 - 0.0021 17.0 12.0 0.0021 17.0 8.4 2.0 2 0 0 2 2 2 1 BAF1 / ABF1 chromatin reorganising factor DUF3437 PF11919.3 KEG12149.1 - 0.023 14.4 4.8 0.026 14.2 0.3 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) Suf PF05843.9 KEG12149.1 - 1 9.0 5.2 2.2 7.9 3.6 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Cyto_ox_2 PF02322.10 KEG12150.1 - 0.037 13.2 0.1 0.04 13.0 0.1 1.0 1 0 0 1 1 1 0 Cytochrome oxidase subunit II SSFA2_C PF14723.1 KEG12150.1 - 0.12 12.0 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus PerC PF06069.6 KEG12151.1 - 0.0065 16.4 0.8 0.45 10.5 0.1 2.3 2 0 0 2 2 2 2 PerC transcriptional activator PMEI PF04043.10 KEG12151.1 - 0.028 14.3 0.4 0.043 13.7 0.3 1.3 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor Mak10 PF04112.8 KEG12152.1 - 4.9e-07 29.1 0.0 1.6e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Aha1_N PF09229.6 KEG12153.1 - 8.4e-30 103.3 0.0 1.2e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 KEG12153.1 - 1.1e-13 51.3 0.0 1.9e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein TMEM171 PF15471.1 KEG12153.1 - 0.15 10.7 0.5 0.22 10.2 0.4 1.1 1 0 0 1 1 1 0 Transmembrane protein family 171 Amino_oxidase PF01593.19 KEG12154.1 - 3.5e-09 36.2 0.0 0.0002 20.5 0.0 2.2 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KEG12154.1 - 3.9e-09 36.3 0.1 1.2e-08 34.8 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEG12154.1 - 0.00074 18.5 0.0 0.0021 16.9 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEG12154.1 - 0.0015 18.6 0.0 0.0097 15.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEG12154.1 - 0.0033 17.3 0.0 0.012 15.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEG12154.1 - 0.0036 17.0 0.0 0.059 13.1 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.9 KEG12154.1 - 0.1 11.0 0.0 0.16 10.4 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Lipase_3 PF01764.20 KEG12155.1 - 8.6e-13 48.0 0.0 1.5e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 KEG12155.1 - 0.0011 18.8 0.0 0.0023 17.8 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KEG12155.1 - 0.026 14.1 0.3 0.043 13.3 0.2 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.2 KEG12155.1 - 0.037 13.7 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Metallophos PF00149.23 KEG12156.1 - 3e-37 127.9 0.1 3e-37 127.9 0.1 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 KEG12156.1 - 4e-23 81.2 0.0 9.7e-23 80.0 0.0 1.7 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_11 PF13414.1 KEG12156.1 - 2.5e-22 78.3 5.4 9.6e-15 53.9 2.0 2.3 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 KEG12156.1 - 6.6e-16 57.1 1.5 1.1e-05 24.8 0.0 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEG12156.1 - 1.9e-14 52.3 3.2 6.5e-05 22.5 0.0 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KEG12156.1 - 1.3e-08 35.2 7.0 0.00047 20.7 0.1 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat BTAD PF03704.12 KEG12156.1 - 3.6e-07 30.6 0.6 6.2e-07 29.8 0.4 1.3 1 0 0 1 1 1 1 Bacterial transcriptional activator domain TPR_12 PF13424.1 KEG12156.1 - 7.1e-05 22.6 1.3 0.014 15.3 0.1 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KEG12156.1 - 0.00037 20.8 0.5 0.47 11.2 0.0 3.3 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEG12156.1 - 0.00072 19.1 0.2 0.046 13.5 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 KEG12156.1 - 0.0022 17.0 0.1 0.84 8.6 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 KEG12156.1 - 0.0023 18.2 0.5 0.59 10.7 0.0 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEG12156.1 - 0.0058 16.3 0.0 1.2 9.1 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEG12156.1 - 0.0076 16.5 0.5 6.2 7.2 0.4 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 KEG12156.1 - 0.017 14.9 0.1 0.16 11.8 0.0 2.2 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 KEG12156.1 - 0.038 14.1 0.9 0.74 10.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 KEG12156.1 - 0.16 12.0 1.4 45 4.2 0.2 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 YfiO PF13525.1 KEG12156.1 - 0.2 11.0 0.6 5.7 6.3 0.0 2.2 1 1 1 2 2 2 0 Outer membrane lipoprotein DUF21 PF01595.15 KEG12157.1 - 1.7e-22 79.5 0.3 4.2e-22 78.3 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF21 CBS PF00571.23 KEG12157.1 - 8.8e-05 22.2 0.5 0.62 9.8 0.0 3.5 3 0 0 3 3 3 2 CBS domain cNMP_binding PF00027.24 KEG12157.1 - 0.14 11.9 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain DUF21 PF01595.15 KEG12158.1 - 3e-29 101.6 4.0 5.4e-29 100.7 2.8 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 KEG12158.1 - 0.0037 17.0 0.8 2.9 7.7 0.1 3.4 3 0 0 3 3 3 1 CBS domain cNMP_binding PF00027.24 KEG12158.1 - 0.0067 16.2 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain TF_Zn_Ribbon PF08271.7 KEG12159.1 - 0.08 12.2 0.8 0.18 11.1 0.5 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding DUF726 PF05277.7 KEG12160.1 - 1.2e-53 182.2 17.0 3e-50 171.0 0.0 3.1 2 1 1 3 3 3 3 Protein of unknown function (DUF726) PNK3P PF08645.6 KEG12161.1 - 1.7e-07 30.8 0.0 2.6e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase Glyco_hydro_31 PF01055.21 KEG12162.1 - 1.3e-142 475.7 2.9 1.6e-142 475.4 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KEG12162.1 - 1.6e-15 56.6 0.1 4.4e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 Galactose mutarotase-like 3Beta_HSD PF01073.14 KEG12163.1 - 5.6e-09 35.0 0.0 8e-09 34.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KEG12163.1 - 2.4e-07 30.9 0.0 4e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 KEG12163.1 - 2.4e-05 24.6 0.0 4.6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 KEG12163.1 - 0.00037 20.4 0.0 0.00073 19.4 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 KEG12163.1 - 0.0041 16.0 0.0 1.7 7.4 0.0 2.8 2 1 0 2 2 2 2 RmlD substrate binding domain DapB_N PF01113.15 KEG12163.1 - 0.01 15.7 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 KEG12163.1 - 0.033 13.8 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 KR domain NmrA PF05368.8 KEG12163.1 - 0.058 12.6 0.0 0.093 11.9 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Epimerase PF01370.16 KEG12163.1 - 0.067 12.6 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family zf-CCCH PF00642.19 KEG12164.1 - 0.0057 16.3 8.4 0.46 10.2 1.3 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KEG12164.1 - 1.2 9.2 6.8 2.1 8.4 0.7 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type zf-CCCH PF00642.19 KEG12165.1 - 0.12 12.1 10.1 0.23 11.1 0.6 3.4 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) NAD_binding_1 PF00175.16 KEG12167.1 - 1.4e-24 86.7 0.0 2.3e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KEG12167.1 - 3.5e-18 65.5 0.0 9e-18 64.2 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain FAD_binding_9 PF08021.6 KEG12167.1 - 0.06 13.3 0.0 0.092 12.7 0.0 1.3 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain NAD_binding_6 PF08030.7 KEG12167.1 - 0.074 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 KEG12168.1 - 4.7e-22 78.6 0.0 6.8e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KEG12168.1 - 1.1e-18 67.2 0.0 1.6e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KEG12168.1 - 0.00052 19.9 0.0 0.0015 18.4 0.0 1.7 2 0 0 2 2 2 1 Ferric reductase NAD binding domain SUI1 PF01253.17 KEG12169.1 - 5.5e-15 54.9 0.1 3.2e-14 52.4 0.0 2.2 2 0 0 2 2 2 1 Translation initiation factor SUI1 PUA PF01472.15 KEG12169.1 - 0.12 12.1 0.1 0.45 10.2 0.0 2.1 2 0 0 2 2 2 0 PUA domain LRR_6 PF13516.1 KEG12170.1 - 0.00085 19.1 1.0 4 7.8 0.0 3.5 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.2 KEG12170.1 - 0.063 12.9 0.1 8.6 6.0 0.0 2.6 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEG12170.1 - 0.12 12.4 0.1 13 6.2 0.0 2.9 3 0 0 3 3 3 0 Leucine Rich Repeat Cytochrom_c3_2 PF14537.1 KEG12171.1 - 0.0014 18.8 11.9 0.029 14.7 3.1 2.6 1 1 2 3 3 3 3 Cytochrome c3 zf-CHY PF05495.7 KEG12171.1 - 0.0034 17.5 13.7 0.74 10.0 0.3 3.4 1 1 3 4 4 4 4 CHY zinc finger Cytochrome_C7 PF14522.1 KEG12171.1 - 0.0035 16.9 19.3 0.013 15.0 4.5 3.2 1 1 3 4 4 4 3 Cytochrome c7 DUF3133 PF11331.3 KEG12171.1 - 0.0037 16.7 21.7 0.66 9.5 0.4 4.4 3 1 2 5 5 5 3 Protein of unknown function (DUF3133) Mu-like_Com PF10122.4 KEG12171.1 - 0.012 14.6 0.2 0.012 14.6 0.1 3.5 3 2 1 4 4 4 0 Mu-like prophage protein Com DUF2296 PF10058.4 KEG12171.1 - 0.051 13.3 8.7 0.33 10.7 0.1 3.4 3 0 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) zf-Sec23_Sec24 PF04810.10 KEG12171.1 - 0.55 9.8 15.0 0.66 9.5 0.1 3.7 4 0 0 4 4 4 0 Sec23/Sec24 zinc finger Cytochrom_C PF00034.16 KEG12171.1 - 4.1 8.3 10.2 0.71 10.7 0.2 3.1 3 1 0 3 3 3 0 Cytochrome c Pkinase PF00069.20 KEG12172.1 - 5e-63 212.6 0.0 6.2e-63 212.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG12172.1 - 2e-34 118.8 0.0 2.7e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG12172.1 - 2.1e-05 23.6 0.0 2.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEG12172.1 - 0.016 14.9 0.1 0.37 10.4 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 KEG12172.1 - 0.13 11.2 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Herpes_pp85 PF04637.7 KEG12172.1 - 0.17 10.1 1.6 0.22 9.7 1.1 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Ribosomal_L22 PF00237.14 KEG12173.1 - 1.4e-12 47.4 0.0 2.1e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e CAP_N PF01213.14 KEG12175.1 - 0.14 11.4 3.4 0.16 11.2 2.4 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 KEG12175.1 - 1.2 8.4 5.9 1.4 8.1 4.1 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF663 PF04950.7 KEG12177.1 - 1.5e-79 267.0 0.0 2.1e-79 266.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KEG12177.1 - 5.2e-20 70.7 0.0 8.9e-20 70.0 0.0 1.4 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Acyl-CoA_dh_N PF02771.11 KEG12178.1 - 4.5e-08 33.6 0.1 1.2e-07 32.2 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KEG12178.1 - 1.2e-07 31.1 0.0 2.8e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain MaoC_dehydratas PF01575.14 KEG12180.1 - 3.2e-21 74.9 0.0 4.5e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 KEG12180.1 - 4.3e-10 39.4 0.0 8.2e-10 38.5 0.0 1.5 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase 4HBT PF03061.17 KEG12180.1 - 0.0062 16.6 0.2 0.018 15.1 0.0 2.0 2 1 0 2 2 2 1 Thioesterase superfamily 4HBT_2 PF13279.1 KEG12180.1 - 0.089 13.2 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 Thioesterase-like superfamily Pax2_C PF12403.3 KEG12180.1 - 0.14 11.8 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Paired-box protein 2 C terminal SIN1 PF05422.7 KEG12181.1 - 0.02 13.4 0.0 0.03 12.8 0.0 1.2 1 0 0 1 1 1 0 Stress-activated map kinase interacting protein 1 (SIN1) DUF1651 PF07864.6 KEG12181.1 - 0.08 13.0 0.1 0.38 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1651) LicD PF04991.8 KEG12182.1 - 1.7e-06 28.2 0.3 2.5e-05 24.4 0.1 2.1 2 0 0 2 2 2 1 LicD family EamA PF00892.15 KEG12183.1 - 2.7e-12 46.8 26.8 4.2e-08 33.2 3.1 2.7 3 0 0 3 3 3 2 EamA-like transporter family DUF914 PF06027.7 KEG12183.1 - 1.9e-09 36.8 10.0 1.4e-08 34.0 6.9 2.0 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 KEG12183.1 - 3.1e-06 26.3 9.6 5.4e-06 25.5 6.7 1.3 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.1 KEG12183.1 - 3.9e-06 27.0 24.3 2.7e-05 24.3 2.4 2.9 3 1 0 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 KEG12183.1 - 0.00022 20.8 19.0 0.00063 19.4 0.9 2.7 3 0 0 3 3 3 2 Triose-phosphate Transporter family DUF2919 PF11143.3 KEG12183.1 - 0.49 10.2 5.9 0.56 10.0 0.0 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF2919) Rav1p_C PF12234.3 KEG12185.1 - 6.1e-36 123.7 0.1 1.1e-35 122.9 0.1 1.3 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 KEG12185.1 - 6.4e-05 22.6 2.0 0.019 14.8 0.1 3.9 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF1674 PF07896.7 KEG12186.1 - 6.9e-13 48.5 0.0 1.2e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) UPF0506 PF11703.3 KEG12187.1 - 0.064 13.2 3.6 0.13 12.1 2.5 1.4 1 0 0 1 1 1 0 UPF0506 WD40 PF00400.27 KEG12188.1 - 0.026 14.4 16.1 1.8 8.5 0.1 6.7 6 1 0 6 6 6 0 WD domain, G-beta repeat MCD PF05292.6 KEG12189.1 - 1.2e-62 211.6 0.1 1.2e-61 208.3 0.0 2.2 1 1 0 1 1 1 1 Malonyl-CoA decarboxylase (MCD) zf-RING_2 PF13639.1 KEG12190.1 - 0.0024 17.6 3.6 0.0037 17.0 0.5 3.0 2 0 0 2 2 2 1 Ring finger domain RNA_pol_Rpb1_7 PF04990.7 KEG12190.1 - 0.23 11.1 0.0 0.51 10.0 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 7 Flu_NP PF00506.13 KEG12191.1 - 0.051 12.0 0.1 0.084 11.3 0.0 1.2 1 0 0 1 1 1 0 Influenza virus nucleoprotein EF-hand_1 PF00036.27 KEG12192.1 - 9.1e-27 90.2 12.2 1.2e-09 36.7 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 KEG12192.1 - 7.9e-23 78.2 8.0 5.2e-09 35.2 0.1 4.5 5 0 0 5 5 5 3 EF-hand domain EF-hand_7 PF13499.1 KEG12192.1 - 1e-20 73.5 8.0 2.5e-11 43.5 2.1 2.6 2 1 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.1 KEG12192.1 - 1.7e-20 72.3 11.0 2.2e-13 49.5 0.7 3.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 KEG12192.1 - 9.7e-19 65.7 8.8 1.3e-06 27.4 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.1 KEG12192.1 - 2.8e-12 46.3 0.1 7.2e-08 32.2 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KEG12192.1 - 1.2e-05 24.9 0.5 0.087 12.5 0.0 2.4 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand MgtE_N PF03448.12 KEG12192.1 - 0.021 15.1 2.4 0.39 11.0 0.6 2.3 2 0 0 2 2 2 0 MgtE intracellular N domain Toprim_2 PF13155.1 KEG12192.1 - 0.027 14.7 0.2 10 6.5 0.1 2.2 2 0 0 2 2 2 0 Toprim-like DUF853 PF05872.7 KEG12192.1 - 0.058 11.7 0.2 3 6.0 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) DUF3008 PF11450.3 KEG12192.1 - 0.7 10.0 2.9 0.72 10.0 0.1 2.4 3 0 0 3 3 2 0 Protein of unknwon function (DUF3008) PAP_assoc PF03828.14 KEG12193.1 - 3.5e-10 39.6 0.0 7.3e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KEG12193.1 - 0.00051 20.3 0.0 0.001 19.3 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF1840 PF08895.6 KEG12193.1 - 0.064 13.2 1.5 0.46 10.5 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1840) DUF755 PF05501.6 KEG12193.1 - 0.83 9.7 19.2 0.031 14.3 8.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF755) SR-25 PF10500.4 KEG12193.1 - 2.7 7.4 23.7 0.2 11.1 12.5 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF1675 PF07897.6 KEG12193.1 - 8.9 6.0 16.1 7.1 6.4 3.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) Methyltransf_31 PF13847.1 KEG12194.1 - 0.076 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_S24 PF00717.18 KEG12195.1 - 1.1e-09 37.8 0.0 1.5e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase S24-like SET PF00856.23 KEG12196.1 - 1.8e-10 41.3 0.3 3.9e-09 37.0 0.2 2.3 1 1 0 1 1 1 1 SET domain Glycos_transf_2 PF00535.21 KEG12197.1 - 2.4e-30 105.4 0.0 3e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KEG12197.1 - 1.9e-10 40.9 0.0 2.3e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KEG12197.1 - 0.00053 19.3 0.0 0.00089 18.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.4 KEG12197.1 - 0.0025 16.9 0.0 0.0031 16.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KEG12197.1 - 0.44 10.2 0.0 0.44 10.2 0.0 2.2 1 1 0 2 2 2 0 Glycosyl transferase family group 2 FKBP_C PF00254.23 KEG12198.1 - 3.5e-26 91.0 0.0 4.2e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase LZ_Tnp_IS66 PF13007.2 KEG12199.1 - 0.0044 17.6 1.2 0.0044 17.6 0.8 3.1 3 0 0 3 3 3 1 Transposase C of IS166 homeodomain ADIP PF11559.3 KEG12199.1 - 0.011 15.6 14.7 0.011 15.6 10.2 1.6 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DivIC PF04977.10 KEG12199.1 - 0.11 11.9 13.2 1.1 8.7 2.5 2.6 1 1 1 2 2 2 0 Septum formation initiator APG6 PF04111.7 KEG12199.1 - 0.27 10.2 7.0 0.37 9.8 4.8 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1515 PF07439.6 KEG12199.1 - 0.36 10.6 4.1 0.69 9.7 2.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DUF641 PF04859.7 KEG12199.1 - 0.57 9.9 7.8 0.39 10.4 4.1 1.7 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) TSC22 PF01166.13 KEG12199.1 - 0.69 9.9 7.5 0.45 10.5 0.1 3.1 2 1 1 3 3 3 0 TSC-22/dip/bun family TPR_MLP1_2 PF07926.7 KEG12199.1 - 0.81 9.4 13.5 2 8.1 9.4 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Kinetocho_Slk19 PF12709.2 KEG12199.1 - 2.4 8.2 9.4 4.6 7.3 1.2 2.8 3 0 0 3 3 3 0 Central kinetochore-associated DUF1640 PF07798.6 KEG12199.1 - 3 7.8 11.8 5.4 7.0 7.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) Atg14 PF10186.4 KEG12199.1 - 3 6.7 15.6 2.7 6.8 10.1 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Ead_Ea22 PF13935.1 KEG12199.1 - 4.3 7.6 10.5 3.5 7.9 6.1 1.9 1 1 1 2 2 2 0 Ead/Ea22-like protein Troponin PF00992.15 KEG12199.1 - 8 6.5 18.5 0.046 13.7 4.0 2.9 2 1 1 3 3 3 0 Troponin Paf67 PF10255.4 KEG12200.1 - 2.1e-91 306.8 0.0 3.1e-91 306.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 KEG12200.1 - 0.0065 16.3 0.0 0.17 11.8 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF569 PF04601.8 KEG12200.1 - 0.016 14.6 0.0 0.034 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF569) TPR_6 PF13174.1 KEG12200.1 - 0.086 13.3 0.3 12 6.6 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat FGGY_N PF00370.16 KEG12201.1 - 8.1e-79 264.3 0.0 1e-78 264.0 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 KEG12201.1 - 6.1e-33 114.1 1.1 1.1e-32 113.2 0.8 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.15 KEG12201.1 - 0.0031 16.8 0.1 1.6 7.9 0.0 2.2 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family HSP70 PF00012.15 KEG12201.1 - 0.18 9.6 1.6 6.3 4.5 0.5 2.1 2 0 0 2 2 2 0 Hsp70 protein CH PF00307.26 KEG12202.1 - 1e-07 31.9 0.0 0.012 15.5 0.0 2.4 2 0 0 2 2 2 2 Calponin homology (CH) domain TFIIS_M PF07500.9 KEG12203.1 - 0.074 13.1 0.1 0.58 10.2 0.1 2.1 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS), central domain DUF2939 PF11159.3 KEG12204.1 - 0.0097 16.0 0.0 0.024 14.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2939) Ank_2 PF12796.2 KEG12204.1 - 0.032 14.5 0.0 0.089 13.1 0.0 1.7 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) NUDIX PF00293.23 KEG12205.1 - 1.2e-16 60.6 0.0 2.1e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Dynein_light PF01221.13 KEG12206.1 - 1.2e-26 92.4 1.0 1.5e-26 92.2 0.7 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Transglut_prok PF09017.5 KEG12206.1 - 0.051 12.6 0.0 0.051 12.6 0.0 1.0 1 0 0 1 1 1 0 Microbial transglutaminase ESCRT-II PF05871.7 KEG12207.1 - 3.6e-13 49.6 0.0 8.7e-13 48.3 0.0 1.6 1 1 0 1 1 1 1 ESCRT-II complex subunit Proteasome PF00227.21 KEG12208.1 - 6.7e-28 97.2 0.2 8.6e-28 96.9 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit RNase_HII PF01351.13 KEG12210.1 - 1.1e-25 90.3 0.0 7.3e-15 55.1 0.0 3.2 1 1 0 2 2 2 2 Ribonuclease HII DUF3292 PF11696.3 KEG12210.1 - 0.031 12.1 0.0 0.039 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) PI3_PI4_kinase PF00454.22 KEG12211.1 - 1.8e-43 148.7 0.1 4.1e-43 147.5 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 KEG12211.1 - 6.6e-28 97.7 1.6 6.6e-28 97.7 1.1 3.2 3 1 0 3 3 3 1 FAT domain FATC PF02260.15 KEG12211.1 - 2.2e-10 39.7 0.1 5.2e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 KEG12211.1 - 0.0011 18.8 3.7 24 5.3 0.0 6.0 5 0 0 5 5 5 1 HEAT repeat Arm PF00514.18 KEG12211.1 - 0.04 13.7 1.1 3.6 7.5 0.0 4.5 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat MORN PF02493.15 KEG12213.1 - 0.0001 21.8 22.9 0.015 14.9 0.8 5.8 6 0 0 6 6 6 3 MORN repeat AAA PF00004.24 KEG12214.1 - 4e-05 23.8 0.0 0.00012 22.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KEG12214.1 - 0.00013 22.7 0.0 0.00049 20.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEG12214.1 - 0.0006 19.8 0.6 0.0042 17.0 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KEG12214.1 - 0.00094 19.3 0.1 1.1 9.3 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.9 KEG12214.1 - 0.0021 17.7 0.1 0.56 9.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KEG12214.1 - 0.037 13.4 0.3 0.19 11.1 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein Arch_ATPase PF01637.13 KEG12214.1 - 0.13 11.9 0.0 0.49 10.0 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase zf-rbx1 PF12678.2 KEG12215.1 - 4.6e-05 23.4 1.4 0.00011 22.2 1.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KEG12215.1 - 0.00054 19.7 3.0 0.0016 18.2 2.1 1.9 1 0 0 1 1 1 1 Ring finger domain zf-Apc11 PF12861.2 KEG12215.1 - 0.0058 16.4 2.7 0.016 15.0 1.9 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 KEG12215.1 - 0.045 13.7 2.2 0.15 12.0 1.5 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEG12215.1 - 0.2 11.4 6.8 2.1 8.1 4.7 2.6 1 1 0 1 1 1 0 zinc-RING finger domain RHSP PF07999.6 KEG12216.1 - 1.4e-98 330.3 0.0 2.1e-98 329.8 0.0 1.2 1 0 0 1 1 1 1 Retrotransposon hot spot protein Macro_2 PF14519.1 KEG12216.1 - 0.0029 16.7 0.0 0.0049 16.0 0.0 1.3 1 0 0 1 1 1 1 Macro-like domain DUF3115 PF11312.3 KEG12216.1 - 0.2 10.4 0.1 0.32 9.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3115) GDC-P PF02347.11 KEG12217.1 - 1.6e-176 587.2 0.0 1.5e-165 551.0 0.0 3.1 3 0 0 3 3 3 3 Glycine cleavage system P-protein Pkinase PF00069.20 KEG12218.1 - 1.1e-61 208.3 0.0 1.2e-61 208.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG12218.1 - 3.7e-24 85.2 0.0 4.9e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG12218.1 - 0.00046 19.2 0.0 0.00061 18.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KEG12218.1 - 0.16 11.0 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FYVE PF01363.16 KEG12220.1 - 4.9e-18 64.7 11.3 8.3e-18 64.0 7.9 1.4 1 0 0 1 1 1 1 FYVE zinc finger HypA PF01155.14 KEG12220.1 - 4 7.1 6.5 1.2 8.8 2.5 1.6 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Actin PF00022.14 KEG12222.1 - 0.0021 16.5 0.1 0.014 13.8 0.0 2.1 3 0 0 3 3 3 1 Actin Rhomboid PF01694.17 KEG12225.1 - 0.024 14.6 4.9 0.028 14.4 2.2 2.0 2 1 0 2 2 2 0 Rhomboid family Pribosyltran PF00156.22 KEG12226.1 - 1.9e-17 63.1 0.0 2.6e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KEG12226.1 - 0.014 14.6 0.1 0.019 14.2 0.1 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 KEG12226.1 - 0.032 13.5 0.1 0.077 12.2 0.1 1.5 1 1 0 1 1 1 0 Phosphoribosyl transferase Pribosyltran PF00156.22 KEG12227.1 - 2.4e-14 53.1 0.0 3.8e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KEG12227.1 - 0.00053 19.2 0.0 0.00067 18.9 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 KEG12227.1 - 0.026 13.8 0.0 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase Racemase_4 PF13615.1 KEG12228.1 - 1.6e-20 73.2 0.0 3e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 Putative alanine racemase MCM_bind PF09739.4 KEG12228.1 - 2.2e-12 46.6 0.0 1.7e-11 43.7 0.0 2.3 1 1 0 1 1 1 1 Mini-chromosome maintenance replisome factor Baculo_p24 PF05073.7 KEG12229.1 - 0.25 10.8 2.1 0.67 9.5 1.0 2.0 1 1 0 1 1 1 0 Baculovirus P24 capsid protein NIF PF03031.13 KEG12230.1 - 5.3e-46 156.1 0.0 7.4e-46 155.7 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Ribosomal_L30 PF00327.15 KEG12231.1 - 1.6e-18 65.9 1.0 3.9e-18 64.7 0.7 1.7 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.7 KEG12231.1 - 1.8e-17 63.1 11.0 3.1e-17 62.3 7.6 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain DARPP-32 PF05395.7 KEG12232.1 - 0.019 15.1 2.8 0.026 14.7 2.0 1.1 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 LNS2 PF08235.8 KEG12233.1 - 2e-56 189.8 0.0 3.3e-56 189.2 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 KEG12233.1 - 3.4e-20 71.7 0.0 7.8e-20 70.5 0.0 1.6 1 0 0 1 1 1 1 lipin, N-terminal conserved region AF1Q PF15017.1 KEG12233.1 - 0.075 12.9 6.2 0.031 14.1 0.7 2.8 3 0 0 3 3 3 0 Drug resistance and apoptosis regulator SNARE PF05739.14 KEG12234.1 - 6.7e-05 22.4 3.0 0.00039 20.0 0.2 2.6 2 0 0 2 2 2 1 SNARE domain Guanylin PF02058.10 KEG12234.1 - 0.02 14.9 0.5 0.13 12.3 0.3 2.4 1 1 0 1 1 1 0 Guanylin precursor ACOX PF01756.14 KEG12234.1 - 0.2 10.9 1.4 0.34 10.2 0.2 1.9 1 1 1 2 2 2 0 Acyl-CoA oxidase FTA4 PF13093.1 KEG12234.1 - 0.33 10.3 2.7 0.87 8.9 1.9 1.8 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 GrpE PF01025.14 KEG12234.1 - 1.1 8.7 5.3 5.6 6.4 3.7 2.1 1 1 0 1 1 1 0 GrpE Pentapeptide_2 PF01469.13 KEG12237.1 - 0.00015 21.2 13.9 0.016 14.8 9.6 2.9 1 1 0 1 1 1 1 Pentapeptide repeats (8 copies) GpcrRhopsn4 PF10192.4 KEG12239.1 - 0.039 13.1 1.5 0.085 12.0 1.1 1.4 1 0 0 1 1 1 0 Rhodopsin-like GPCR transmembrane domain RWD PF05773.17 KEG12241.1 - 7.4e-09 35.5 0.2 1.3e-08 34.6 0.1 1.4 1 0 0 1 1 1 1 RWD domain NAAA-beta PF15508.1 KEG12241.1 - 0.00064 20.0 0.0 0.0017 18.6 0.0 1.7 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF2924 PF11149.3 KEG12241.1 - 0.071 13.1 0.4 0.14 12.2 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) MORN PF02493.15 KEG12243.1 - 1.6e-21 74.6 30.0 2.2e-05 23.9 0.4 10.0 10 0 0 10 10 10 7 MORN repeat WW PF00397.21 KEG12243.1 - 0.12 12.2 0.0 0.12 12.2 0.0 2.5 3 0 0 3 3 3 0 WW domain DUF4404 PF14357.1 KEG12244.1 - 0.029 14.7 0.8 2.6 8.5 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) CTP_transf_2 PF01467.21 KEG12245.1 - 0.0011 19.0 0.1 0.0084 16.1 0.0 2.3 2 1 1 3 3 3 1 Cytidylyltransferase DNA_RNApol_7kD PF03604.8 KEG12246.1 - 2e-05 23.9 0.6 3.2e-05 23.2 0.4 1.4 1 1 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit zf-UBR PF02207.15 KEG12246.1 - 0.045 13.4 0.5 0.061 13.0 0.3 1.2 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) NinF PF05810.7 KEG12246.1 - 0.16 11.8 0.6 0.23 11.3 0.4 1.2 1 0 0 1 1 1 0 NinF protein UPF0547 PF10571.4 KEG12246.1 - 0.3 10.8 2.4 0.47 10.1 1.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 zf-RING_3 PF14369.1 KEG12246.1 - 0.59 10.1 2.9 1.1 9.3 2.0 1.5 1 0 0 1 1 1 0 zinc-finger PPR_2 PF13041.1 KEG12247.1 - 3.4e-10 39.7 0.0 0.00017 21.5 0.0 4.3 3 1 2 5 5 5 4 PPR repeat family PPR PF01535.15 KEG12247.1 - 9.7e-09 34.6 0.1 0.029 14.3 0.0 3.4 3 0 0 3 3 3 2 PPR repeat PPR_3 PF13812.1 KEG12247.1 - 1.1e-05 25.2 7.2 0.0014 18.7 0.0 4.7 5 0 0 5 5 5 1 Pentatricopeptide repeat domain PPR_1 PF12854.2 KEG12247.1 - 0.052 13.0 0.0 0.63 9.5 0.0 2.5 2 0 0 2 2 2 0 PPR repeat Tubulin PF00091.20 KEG12248.1 - 1e-53 182.3 0.0 1.4e-53 181.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.1 KEG12248.1 - 0.0022 17.0 0.0 0.0034 16.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin like TM231 PF10149.4 KEG12249.1 - 4.9e-10 38.9 0.3 3.2e-05 23.0 0.4 2.1 2 0 0 2 2 2 2 Transmembrane protein 231 DAO PF01266.19 KEG12250.1 - 3.7e-25 88.6 5.1 5.6e-25 88.0 3.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KEG12250.1 - 1.3e-05 23.8 0.7 1.9e-05 23.3 0.5 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 KEG12250.1 - 5.8e-05 23.0 0.1 0.00011 22.1 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KEG12250.1 - 9.2e-05 21.4 5.4 9.2e-05 21.4 3.7 2.1 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KEG12250.1 - 0.00022 21.1 0.2 0.0006 19.7 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KEG12250.1 - 0.00034 19.8 2.4 0.00054 19.1 1.7 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEG12250.1 - 0.00086 19.4 0.4 0.034 14.2 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEG12250.1 - 0.0081 16.5 0.2 0.039 14.3 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KEG12250.1 - 0.01 14.9 0.2 0.016 14.2 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 KEG12250.1 - 0.041 12.9 0.3 0.1 11.6 0.2 1.6 1 0 0 1 1 1 0 Thi4 family NAD_binding_7 PF13241.1 KEG12250.1 - 0.042 14.0 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding Lycopene_cycl PF05834.7 KEG12250.1 - 0.046 12.6 0.9 0.088 11.7 0.6 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.9 KEG12250.1 - 0.067 12.5 0.9 0.17 11.2 0.7 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.17 KEG12250.1 - 0.11 11.2 1.2 0.18 10.6 0.9 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 KEG12250.1 - 1 8.9 4.3 0.37 10.4 1.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_8 PF05148.10 KEG12251.1 - 1.6e-52 178.2 0.0 2.1e-52 177.9 0.0 1.1 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 KEG12251.1 - 6.9e-09 36.0 0.0 1.8e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEG12251.1 - 0.00026 20.7 0.0 0.0016 18.1 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEG12251.1 - 0.00073 18.7 0.0 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 KEG12251.1 - 0.0038 16.8 0.2 0.37 10.3 0.2 2.3 1 1 0 1 1 1 1 Methyltransferase domain B12-binding PF02310.14 KEG12251.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 B12 binding domain DUF948 PF06103.6 KEG12252.1 - 4.4 7.2 14.7 2.1 8.2 0.1 4.8 3 3 0 3 3 3 0 Bacterial protein of unknown function (DUF948) PSP1 PF04468.7 KEG12255.1 - 8.4e-32 109.0 0.1 1.5e-31 108.2 0.1 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region NIF3 PF01784.13 KEG12256.1 - 2.4e-60 204.0 0.0 2.9e-60 203.8 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) DUF2090 PF09863.4 KEG12256.1 - 0.055 12.2 0.0 0.086 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2090) Trp_leader1 PF08055.6 KEG12257.1 - 0.66 9.5 4.8 1.2 8.6 3.3 1.4 1 0 0 1 1 1 0 Tryptophan leader peptide Pkinase PF00069.20 KEG12258.1 - 1.2e-51 175.4 0.0 1.4e-51 175.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG12258.1 - 3.1e-25 88.7 0.0 4e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG12258.1 - 7.2e-07 28.4 0.0 1.2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEG12258.1 - 1.2e-06 28.5 0.0 3.6e-06 26.9 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KEG12258.1 - 0.003 16.4 0.0 0.0045 15.8 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Choline_kinase PF01633.15 KEG12258.1 - 0.021 14.3 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 KEG12258.1 - 0.079 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 KEG12258.1 - 0.099 11.6 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family tRNA-synt_2b PF00587.20 KEG12259.1 - 2.3e-29 102.2 0.0 3.5e-29 101.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 KEG12259.1 - 5.3e-19 68.2 1.6 1.2e-14 54.2 0.1 2.5 1 1 1 2 2 2 2 Seryl-tRNA synthetase N-terminal domain MORN PF02493.15 KEG12260.1 - 2.8e-51 168.2 61.9 3.9e-09 35.7 0.1 10.6 10 0 0 10 10 10 10 MORN repeat RRM_1 PF00076.17 KEG12261.1 - 0.00017 21.1 0.0 0.00035 20.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BORG_CEP PF14957.1 KEG12261.1 - 0.3 12.0 1.7 2.5 9.0 0.0 2.3 2 1 0 2 2 2 0 Cdc42 effector GRIP PF01465.15 KEG12262.1 - 1.2e-15 56.6 0.1 3.3e-15 55.3 0.1 1.8 1 0 0 1 1 1 1 GRIP domain Filament PF00038.16 KEG12262.1 - 0.00045 19.7 5.3 0.00045 19.7 3.6 7.7 3 1 5 8 8 8 4 Intermediate filament protein IncA PF04156.9 KEG12262.1 - 0.00098 18.7 4.7 0.00098 18.7 3.3 6.3 4 1 2 6 6 6 3 IncA protein Seryl_tRNA_N PF02403.17 KEG12262.1 - 0.0022 18.0 2.5 0.0022 18.0 1.7 8.4 6 3 2 8 8 8 3 Seryl-tRNA synthetase N-terminal domain CENP-F_leu_zip PF10473.4 KEG12262.1 - 0.0087 15.9 15.1 0.0087 15.9 10.4 7.5 5 1 2 7 7 7 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RmuC PF02646.11 KEG12262.1 - 0.029 13.2 0.1 0.029 13.2 0.1 6.6 6 1 0 7 7 7 0 RmuC family Prp19 PF08606.6 KEG12262.1 - 0.48 10.1 16.7 0.73 9.6 0.1 5.1 5 0 0 5 5 5 0 Prp19/Pso4-like Pkinase PF00069.20 KEG12263.1 - 6.9e-42 143.3 0.0 8.5e-29 100.4 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEG12263.1 - 3.7e-16 58.9 0.0 5.6e-10 38.7 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase RWD PF05773.17 KEG12263.1 - 1.5e-07 31.3 0.0 3.9e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 RWD domain APH PF01636.18 KEG12263.1 - 0.0022 17.7 0.1 0.0077 15.9 0.1 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KEG12263.1 - 0.038 12.9 0.0 0.13 11.1 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.9 KEG12263.1 - 0.051 12.6 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NCD1 PF04904.8 KEG12263.1 - 0.061 13.0 0.1 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) TFIIF_alpha PF05793.7 KEG12263.1 - 0.31 9.3 4.9 0.46 8.7 3.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SNF2_N PF00176.18 KEG12264.1 - 1.5e-27 96.1 0.1 3.5e-27 94.9 0.1 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain HNH PF01844.18 KEG12264.1 - 2.9e-09 36.6 0.5 1.3e-08 34.5 0.0 2.4 2 0 0 2 2 2 1 HNH endonuclease Helicase_C PF00271.26 KEG12264.1 - 3.2e-05 23.7 0.0 6.3e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEG12264.1 - 0.23 11.2 0.0 1.1 9.0 0.0 2.1 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit ABC_tran PF00005.22 KEG12265.1 - 1.2e-28 100.1 0.0 1.9e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KEG12265.1 - 7.3e-09 35.9 0.5 7.3e-05 22.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KEG12265.1 - 0.00012 21.3 0.8 0.0045 16.2 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 KEG12265.1 - 0.00092 19.0 0.9 0.0035 17.2 0.1 2.3 2 1 0 2 2 1 1 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 KEG12265.1 - 0.0014 17.8 0.0 0.0019 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KEG12265.1 - 0.0046 16.4 0.5 0.012 15.0 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_10 PF12846.2 KEG12265.1 - 0.013 14.9 0.3 0.18 11.1 0.1 2.1 2 0 0 2 2 2 0 AAA-like domain AAA_16 PF13191.1 KEG12265.1 - 0.029 14.3 0.2 0.057 13.4 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 KEG12265.1 - 0.033 14.3 3.3 0.71 10.0 2.3 2.3 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KEG12265.1 - 0.034 13.6 0.2 0.15 11.5 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_25 PF13481.1 KEG12265.1 - 0.043 13.2 1.1 0.36 10.1 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KEG12265.1 - 0.059 14.1 0.0 0.14 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain Patatin PF01734.17 KEG12265.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.4 1 1 0 1 1 1 0 Patatin-like phospholipase RNA_helicase PF00910.17 KEG12265.1 - 0.15 12.2 0.0 0.38 10.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 KEG12265.1 - 0.15 11.6 0.0 0.34 10.5 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase AAA_15 PF13175.1 KEG12265.1 - 0.18 10.8 0.0 2.4 7.0 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain ABC_ATPase PF09818.4 KEG12265.1 - 0.6 8.6 3.6 13 4.2 0.2 2.8 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA_18 PF13238.1 KEG12265.1 - 0.67 10.2 2.3 2 8.7 1.6 2.1 1 1 0 1 1 1 0 AAA domain Hexapep PF00132.19 KEG12266.1 - 8.1e-13 47.2 0.7 1.1e-05 24.6 0.0 3.4 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) D5_N PF08706.6 KEG12266.1 - 0.067 13.2 0.2 0.1 12.6 0.1 1.2 1 0 0 1 1 1 0 D5 N terminal like COPIIcoated_ERV PF07970.7 KEG12267.1 - 1.1e-52 178.8 0.6 2.2e-52 177.8 0.1 1.6 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KEG12267.1 - 1.6e-26 92.0 0.0 4.6e-26 90.6 0.0 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) HALZ PF02183.13 KEG12268.1 - 0.0028 17.3 1.9 0.0028 17.3 1.3 3.0 3 1 1 4 4 4 1 Homeobox associated leucine zipper THF_DHG_CYH_C PF02882.14 KEG12269.1 - 3.7e-62 208.1 0.3 4.9e-62 207.7 0.2 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 KEG12269.1 - 1e-37 128.7 0.1 1.5e-37 128.2 0.1 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.10 KEG12269.1 - 0.075 11.7 0.4 0.11 11.2 0.3 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Cyclin_N PF00134.18 KEG12270.1 - 5.7e-28 97.0 0.3 1e-27 96.1 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain IU_nuc_hydro PF01156.14 KEG12271.1 - 4.3e-13 49.1 0.1 1.1e-12 47.7 0.1 1.6 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Vps52 PF04129.7 KEG12272.1 - 2.1e-57 194.8 0.0 1.6e-20 73.1 0.0 3.1 3 0 0 3 3 3 3 Vps52 / Sac2 family Sec3_C PF09763.4 KEG12272.1 - 0.00037 18.7 0.0 0.58 8.2 0.0 2.3 2 0 0 2 2 2 2 Exocyst complex component Sec3 TPR_11 PF13414.1 KEG12274.1 - 1.2e-66 220.2 36.4 1.8e-11 43.4 0.1 11.2 5 4 8 13 13 13 11 TPR repeat TPR_2 PF07719.12 KEG12274.1 - 4.7e-52 169.7 41.7 0.0011 18.6 0.0 16.9 16 1 1 17 17 17 14 Tetratricopeptide repeat TPR_1 PF00515.23 KEG12274.1 - 3.4e-41 137.2 30.7 0.00014 21.2 0.0 16.2 15 1 0 15 15 15 12 Tetratricopeptide repeat TPR_16 PF13432.1 KEG12274.1 - 4.3e-33 113.2 39.8 3.4e-06 27.5 3.2 10.8 4 3 9 13 13 13 11 Tetratricopeptide repeat TPR_8 PF13181.1 KEG12274.1 - 6e-29 97.6 17.1 0.17 11.7 0.0 14.2 13 3 2 15 15 14 8 Tetratricopeptide repeat TPR_12 PF13424.1 KEG12274.1 - 1.1e-28 98.9 45.5 2.6e-07 30.4 0.4 10.6 4 2 9 13 13 13 10 Tetratricopeptide repeat TPR_9 PF13371.1 KEG12274.1 - 1.7e-23 82.2 35.2 0.00012 21.7 0.1 10.2 5 4 6 11 11 11 9 Tetratricopeptide repeat TPR_17 PF13431.1 KEG12274.1 - 5.5e-18 63.6 27.2 0.07 13.3 0.3 13.9 15 0 0 15 15 14 5 Tetratricopeptide repeat TPR_14 PF13428.1 KEG12274.1 - 5.5e-17 60.7 31.5 0.053 14.1 0.2 13.1 9 3 6 15 15 13 3 Tetratricopeptide repeat TPR_19 PF14559.1 KEG12274.1 - 1.4e-14 54.1 23.6 0.022 15.0 0.3 8.7 5 2 5 10 10 9 5 Tetratricopeptide repeat Apc3 PF12895.2 KEG12274.1 - 3.9e-14 52.5 28.9 3e-05 24.0 0.3 7.3 4 2 3 8 8 8 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KEG12274.1 - 3.6e-09 36.4 21.5 1.1 9.9 0.1 11.1 13 0 0 13 13 10 2 Tetratricopeptide repeat TPR_20 PF14561.1 KEG12274.1 - 5.4e-07 29.6 11.7 0.74 9.9 0.2 6.0 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 KEG12274.1 - 0.0094 15.6 20.4 0.97 9.3 0.1 8.2 8 0 0 8 8 7 1 Tetratricopeptide repeat BTAD PF03704.12 KEG12274.1 - 0.045 14.0 26.3 0.061 13.6 0.4 6.9 4 1 3 9 9 9 0 Bacterial transcriptional activator domain TPR_10 PF13374.1 KEG12274.1 - 0.046 13.6 32.6 0.095 12.6 0.0 9.8 10 1 1 11 11 11 0 Tetratricopeptide repeat Clathrin PF00637.15 KEG12274.1 - 0.085 12.4 0.9 1.4 8.5 0.0 3.2 3 0 0 3 3 3 0 Region in Clathrin and VPS DUF3808 PF10300.4 KEG12274.1 - 2.4 6.6 5.7 1.8 7.0 0.1 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3808) TPR_4 PF07721.9 KEG12274.1 - 4.3 8.0 30.0 0.57 10.7 0.4 8.8 10 0 0 10 10 9 0 Tetratricopeptide repeat PAP_assoc PF03828.14 KEG12275.1 - 4.9e-17 61.6 0.4 1e-16 60.5 0.3 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KEG12275.1 - 0.00014 22.1 0.0 0.00032 20.9 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain SNase PF00565.12 KEG12276.1 - 0.0029 17.8 0.0 0.0047 17.1 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue 2OG-FeII_Oxy_2 PF13532.1 KEG12277.1 - 2.8e-12 46.8 0.0 3.8e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KEG12277.1 - 9.9e-07 28.9 0.1 4.1e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Mac PF12464.3 KEG12277.1 - 0.19 11.7 1.3 0.34 10.9 0.0 2.0 2 0 0 2 2 2 0 Maltose acetyltransferase Zn_Tnp_IS1595 PF12760.2 KEG12278.1 - 0.0014 18.3 3.5 0.0014 18.3 2.4 2.8 2 1 1 3 3 3 1 Transposase zinc-ribbon domain zf-H2C2_2 PF13465.1 KEG12278.1 - 0.023 14.9 0.4 0.023 14.9 0.3 3.0 2 1 1 3 3 3 0 Zinc-finger double domain DUF3268 PF11672.3 KEG12278.1 - 0.026 14.5 0.2 0.026 14.5 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3268) OrfB_Zn_ribbon PF07282.6 KEG12278.1 - 0.52 10.0 9.5 0.16 11.6 2.6 2.4 1 1 0 2 2 2 0 Putative transposase DNA-binding domain IBR PF01485.16 KEG12278.1 - 7.7 6.4 12.3 1.3e+02 2.5 8.5 2.2 1 1 0 1 1 1 0 IBR domain PseudoU_synth_1 PF01416.15 KEG12279.1 - 8.1e-17 61.5 0.0 1.3e-07 31.9 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase ParA PF10609.4 KEG12280.1 - 1.3e-36 124.3 0.1 2.3e-36 123.5 0.1 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KEG12280.1 - 3.2e-17 62.5 0.0 4.6e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 KEG12280.1 - 2.1e-07 30.3 0.3 8.7e-05 21.7 0.2 2.2 2 0 0 2 2 2 2 ATPase MipZ ArsA_ATPase PF02374.10 KEG12280.1 - 2.2e-06 26.9 0.9 1.5e-05 24.1 0.3 2.2 3 0 0 3 3 3 1 Anion-transporting ATPase AAA_31 PF13614.1 KEG12280.1 - 1.9e-05 24.6 0.1 0.00012 22.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KEG12280.1 - 0.0004 19.8 0.3 0.0013 18.1 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KEG12280.1 - 0.0026 17.4 0.4 0.3 10.8 0.3 2.6 2 0 0 2 2 2 1 Part of AAA domain Fer4_NifH PF00142.13 KEG12280.1 - 0.0064 15.7 0.2 0.013 14.6 0.1 1.5 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MobB PF03205.9 KEG12280.1 - 0.011 15.4 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 KEG12280.1 - 0.018 15.8 0.3 0.036 14.8 0.2 1.5 1 1 0 1 1 1 0 AAA domain AAA_26 PF13500.1 KEG12280.1 - 0.032 13.8 0.1 6.2 6.3 0.3 2.2 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 KEG12280.1 - 0.04 12.6 0.6 0.068 11.9 0.4 1.3 1 0 0 1 1 1 0 ArgK protein NACHT PF05729.7 KEG12280.1 - 0.045 13.4 0.7 0.098 12.3 0.5 1.5 1 0 0 1 1 1 0 NACHT domain APS_kinase PF01583.15 KEG12280.1 - 0.09 12.4 0.1 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Zn_Tnp_IS1595 PF12760.2 KEG12280.1 - 0.097 12.4 0.4 0.25 11.2 0.3 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain AAA_22 PF13401.1 KEG12280.1 - 0.1 12.7 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KEG12280.1 - 0.2 10.5 0.3 0.31 9.8 0.2 1.2 1 0 0 1 1 1 0 NB-ARC domain DUF1358 PF07096.6 KEG12281.1 - 0.00016 21.3 0.5 0.00028 20.5 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1358) Porin_3 PF01459.17 KEG12282.1 - 2.1e-05 23.9 0.0 5e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic porin AAA_33 PF13671.1 KEG12283.1 - 3.4e-11 43.1 0.0 5e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KEG12283.1 - 1.9e-07 30.3 0.0 7.1e-07 28.5 0.0 2.0 1 1 0 1 1 1 1 Zeta toxin KTI12 PF08433.5 KEG12283.1 - 7.7e-07 28.5 0.0 9.6e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 KEG12283.1 - 6.1e-06 27.0 0.1 1.5e-05 25.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KEG12283.1 - 8.5e-05 22.8 0.1 0.00014 22.1 0.1 1.6 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 KEG12283.1 - 0.00032 19.8 0.0 0.00056 19.0 0.0 1.4 1 1 0 1 1 1 1 KaiC AAA_16 PF13191.1 KEG12283.1 - 0.00047 20.1 0.0 0.00059 19.8 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 KEG12283.1 - 0.00048 19.8 0.0 0.00086 19.0 0.0 1.4 1 1 0 1 1 1 1 Archaeal ATPase AAA_5 PF07728.9 KEG12283.1 - 0.00065 19.4 0.0 0.0012 18.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KEG12283.1 - 0.00076 19.6 0.0 0.0015 18.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KEG12283.1 - 0.001 19.2 0.1 0.0048 17.0 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 KEG12283.1 - 0.003 17.1 0.0 0.0044 16.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KEG12283.1 - 0.0044 16.9 0.0 0.0069 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 KEG12283.1 - 0.0056 16.1 0.0 0.012 15.0 0.0 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain cobW PF02492.14 KEG12283.1 - 0.0091 15.4 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.13 KEG12283.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase G-alpha PF00503.15 KEG12283.1 - 0.012 14.3 0.2 0.024 13.3 0.1 1.6 1 1 0 1 1 1 0 G-protein alpha subunit DUF1201 PF06716.6 KEG12283.1 - 0.014 15.1 0.1 0.025 14.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1201) ADK PF00406.17 KEG12283.1 - 0.032 14.1 0.1 6.2 6.6 0.0 2.1 2 0 0 2 2 2 0 Adenylate kinase CPT PF07931.7 KEG12283.1 - 0.034 13.7 0.2 0.18 11.4 0.1 1.9 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein IMS PF00817.15 KEG12283.1 - 0.083 12.6 0.2 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 impB/mucB/samB family AAA_19 PF13245.1 KEG12283.1 - 0.13 11.9 0.0 0.4 10.4 0.0 1.8 2 0 0 2 2 1 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 KEG12283.1 - 0.19 11.1 1.5 9.7 5.6 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family WW PF00397.21 KEG12285.1 - 1.6e-05 24.6 5.9 3.3e-05 23.6 4.1 1.5 1 0 0 1 1 1 1 WW domain eIF3g PF12353.3 KEG12285.1 - 2.9e-05 23.9 14.6 0.0014 18.5 0.5 3.2 1 1 2 3 3 3 2 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_2 PF13696.1 KEG12285.1 - 8.4e-05 21.9 11.0 0.00037 19.9 1.1 3.1 2 1 0 2 2 2 2 Zinc knuckle zf-CCHC PF00098.18 KEG12285.1 - 0.00021 21.0 1.6 0.00021 21.0 1.1 3.1 4 0 0 4 4 4 1 Zinc knuckle zf-CCHC_3 PF13917.1 KEG12285.1 - 0.024 14.3 11.0 0.085 12.5 3.6 2.7 2 0 0 2 2 2 0 Zinc knuckle DUF1059 PF06348.6 KEG12285.1 - 0.11 12.3 0.8 0.23 11.3 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1059) Actino_peptide PF14408.1 KEG12285.1 - 0.17 11.8 6.0 19 5.2 0.0 2.3 2 0 0 2 2 2 0 Ribosomally synthesized peptide in actinomycetes Pap_E4 PF02711.9 KEG12285.1 - 0.91 10.3 8.3 2.2 9.1 0.6 2.8 2 1 1 3 3 3 0 E4 protein DUF35_N PF12172.3 KEG12285.1 - 8.3 6.4 10.9 3.8 7.5 0.4 2.9 2 1 1 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Drf_FH3 PF06367.11 KEG12287.1 - 0.024 14.0 0.3 0.22 10.8 0.0 2.4 2 0 0 2 2 2 0 Diaphanous FH3 Domain CesT PF05932.8 KEG12288.1 - 9.4e-17 60.9 0.0 2.5e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Tir chaperone protein (CesT) family ubiquitin PF00240.18 KEG12288.1 - 1.4e-07 30.7 0.4 4.2e-07 29.2 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 KEG12288.1 - 0.0012 18.5 0.0 0.0032 17.0 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like MMR1 PF08505.5 KEG12288.1 - 0.27 11.2 5.8 0.12 12.4 2.3 1.3 1 1 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein TMPIT PF07851.8 KEG12288.1 - 3.1 6.7 5.6 4.6 6.2 3.9 1.4 1 0 0 1 1 1 0 TMPIT-like protein Epimerase PF01370.16 KEG12290.1 - 7.5e-18 64.8 0.0 1.2e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEG12290.1 - 6.6e-15 55.5 0.2 2.3e-14 53.8 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 KEG12290.1 - 1.2e-08 33.9 0.2 6.6e-08 31.5 0.1 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 KEG12290.1 - 1.5e-07 30.9 0.0 1.3e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family AP_endonuc_2 PF01261.19 KEG12290.1 - 0.012 14.9 0.0 0.024 13.9 0.0 1.5 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel KR PF08659.5 KEG12290.1 - 0.012 15.2 0.0 0.034 13.8 0.0 1.8 1 0 0 1 1 1 0 KR domain adh_short PF00106.20 KEG12290.1 - 0.063 13.1 0.0 0.063 13.1 0.0 2.2 3 1 0 3 3 3 0 short chain dehydrogenase TEX12 PF15219.1 KEG12291.1 - 0.078 12.9 0.3 0.21 11.5 0.2 1.7 1 0 0 1 1 1 0 Testis-expressed 12 GCV_H PF01597.14 KEG12292.1 - 3.6e-05 23.4 0.0 5.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Glycine cleavage H-protein Peptidase_C53 PF05550.6 KEG12292.1 - 0.03 13.7 0.0 0.059 12.8 0.0 1.4 1 0 0 1 1 1 0 Pestivirus Npro endopeptidase C53 UPF0506 PF11703.3 KEG12292.1 - 0.27 11.2 2.6 0.17 11.8 0.3 1.7 2 0 0 2 2 2 0 UPF0506 E1-E2_ATPase PF00122.15 KEG12294.1 - 1.5e-21 76.5 0.0 5e-21 74.7 0.0 2.0 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KEG12294.1 - 5.3e-12 46.6 0.0 1.6e-10 41.7 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEG12294.1 - 2.1e-09 37.8 0.0 8.4e-09 35.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEG12294.1 - 4.2e-08 33.0 0.0 1.1e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KEG12294.1 - 0.0016 18.0 0.1 0.004 16.7 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase NPR2 PF06218.6 KEG12295.1 - 6.1e-06 25.2 0.0 0.0039 15.9 0.0 2.1 2 0 0 2 2 2 2 Nitrogen permease regulator 2 PqqD PF05402.7 KEG12295.1 - 0.046 13.7 0.3 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) Kinesin PF00225.18 KEG12296.1 - 1.8e-94 316.1 1.0 2.8e-92 308.9 0.1 3.1 3 0 0 3 3 3 2 Kinesin motor domain Pkinase PF00069.20 KEG12297.1 - 1.9e-52 177.9 0.0 5e-52 176.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG12297.1 - 1.1e-36 126.2 0.0 1.7e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG12297.1 - 5.5e-06 25.5 0.0 6.7e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Helicase_C PF00271.26 KEG12298.1 - 5.7e-15 54.9 0.0 1.4e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEG12298.1 - 1.9e-10 40.4 0.1 7.2e-10 38.6 0.0 2.0 2 1 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 KEG12298.1 - 3e-09 36.9 0.0 8.3e-08 32.2 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.11 KEG12298.1 - 0.0077 15.4 0.1 0.057 12.6 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein IstB_IS21 PF01695.12 KEG12298.1 - 0.033 13.6 0.0 0.11 11.8 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_22 PF13401.1 KEG12298.1 - 0.035 14.2 0.1 0.55 10.3 0.0 2.8 2 1 0 2 2 2 0 AAA domain EF-hand_7 PF13499.1 KEG12299.1 - 9.2e-18 64.1 0.8 0.00035 20.6 0.0 4.4 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.27 KEG12299.1 - 2.6e-17 60.7 0.2 3.5e-05 22.8 0.0 5.5 6 0 0 6 6 6 4 EF hand EF-hand_8 PF13833.1 KEG12299.1 - 1.3e-16 59.8 4.1 4.4e-07 29.4 0.0 5.3 5 0 0 5 5 5 3 EF-hand domain pair EF-hand_6 PF13405.1 KEG12299.1 - 2.8e-16 57.8 2.4 0.023 14.5 0.0 6.3 7 0 0 7 7 7 4 EF-hand domain EF-hand_5 PF13202.1 KEG12299.1 - 7e-10 37.7 0.0 0.00044 19.4 0.0 5.3 5 0 0 5 5 5 1 EF hand EF-hand_9 PF14658.1 KEG12299.1 - 0.09 12.7 0.0 18 5.3 0.0 3.8 4 0 0 4 4 4 0 EF-hand domain EF-hand_4 PF12763.2 KEG12299.1 - 0.094 12.4 0.0 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand DUF2953 PF11167.3 KEG12299.1 - 0.41 10.5 1.8 44 4.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2953) AAA PF00004.24 KEG12300.1 - 3.5e-14 53.1 0.0 1.5e-07 31.7 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEG12300.1 - 0.00011 22.2 0.4 0.00063 19.7 0.0 2.3 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KEG12300.1 - 0.00034 20.7 0.0 0.00082 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KEG12300.1 - 0.0016 18.1 0.0 0.0038 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KEG12300.1 - 0.0038 16.9 0.0 0.014 15.1 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 KEG12300.1 - 0.0082 16.9 2.8 0.011 16.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KEG12300.1 - 0.02 15.0 0.0 0.04 14.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 KEG12300.1 - 0.024 14.3 0.0 0.061 12.9 0.0 1.6 2 0 0 2 2 1 0 NACHT domain AAA_28 PF13521.1 KEG12300.1 - 0.032 14.1 0.0 0.092 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Nitr_red_assoc PF09655.5 KEG12300.1 - 0.062 13.6 0.1 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) Arch_ATPase PF01637.13 KEG12300.1 - 0.063 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_24 PF13479.1 KEG12300.1 - 0.072 12.6 0.1 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KEG12300.1 - 0.097 12.5 0.0 0.32 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KEG12300.1 - 0.13 12.2 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KEG12300.1 - 0.15 11.1 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 KaiC Bac_DnaA PF00308.13 KEG12300.1 - 0.16 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein Nop14 PF04147.7 KEG12300.1 - 0.23 9.3 10.6 0.31 8.9 7.3 1.1 1 0 0 1 1 1 0 Nop14-like family PPV_E1_C PF00519.12 KEG12300.1 - 0.28 9.7 0.0 0.45 9.0 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase Rad17 PF03215.10 KEG12300.1 - 0.32 9.6 0.0 0.47 9.0 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Sigma70_ner PF04546.8 KEG12300.1 - 1.6 8.3 6.9 2.6 7.6 4.8 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region CobT PF06213.7 KEG12300.1 - 3.8 6.5 13.5 6.5 5.8 9.4 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Daxx PF03344.10 KEG12300.1 - 3.9 5.8 10.5 5.9 5.2 7.3 1.2 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 KEG12300.1 - 4.2 5.2 8.0 6.8 4.5 5.6 1.3 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 KEG12300.1 - 7.4 6.0 11.5 14 5.1 8.0 1.4 1 0 0 1 1 1 0 Nucleoplasmin Histone PF00125.19 KEG12301.1 - 1.6e-19 69.7 0.1 2.2e-19 69.3 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KEG12301.1 - 0.01 15.8 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ribosomal_L29 PF00831.18 KEG12301.1 - 0.085 12.5 0.1 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal L29 protein Prp18 PF02840.10 KEG12303.1 - 4.3e-12 46.0 0.0 8.4e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Prp18 domain IQ PF00612.22 KEG12304.1 - 0.00063 19.1 1.2 0.0023 17.4 0.8 2.1 1 0 0 1 1 1 1 IQ calmodulin-binding motif S1-P1_nuclease PF02265.11 KEG12305.1 - 2.4e-62 210.8 0.0 2.8e-62 210.6 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease GPI PF06560.6 KEG12305.1 - 0.12 11.3 0.2 0.18 10.8 0.1 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) DUF2498 PF10692.4 KEG12306.1 - 0.0095 15.5 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2498) 7kD_DNA_binding PF02294.13 KEG12306.1 - 0.057 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 7kD DNA-binding domain Kinesin PF00225.18 KEG12307.1 - 2.2e-84 283.0 0.0 4.7e-84 281.9 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain DEAD PF00270.24 KEG12307.1 - 0.04 13.4 0.7 0.13 11.7 0.0 2.1 2 0 0 2 2 2 0 DEAD/DEAH box helicase Sec8_exocyst PF04048.9 KEG12307.1 - 0.13 11.9 6.9 0.36 10.4 2.8 2.6 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain PSP1 PF04468.7 KEG12309.1 - 3.3e-14 52.6 0.1 4.7e-14 52.1 0.1 1.2 1 0 0 1 1 1 1 PSP1 C-terminal conserved region RIO1 PF01163.17 KEG12310.1 - 3.9e-45 153.5 0.0 7.3e-45 152.6 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 KEG12310.1 - 8.9e-31 105.8 0.1 2e-30 104.7 0.1 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 KEG12310.1 - 1e-12 48.3 0.1 2.1e-06 27.6 0.1 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KEG12310.1 - 7.5e-05 21.8 3.4 0.00017 20.6 0.0 3.0 3 1 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family PSK_trans_fac PF07704.6 KEG12310.1 - 0.08 13.6 2.0 5.9 7.6 1.0 2.8 2 0 0 2 2 2 0 Rv0623-like transcription factor Ribosomal_60s PF00428.14 KEG12310.1 - 0.18 12.2 7.3 0.44 10.9 5.1 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Prothymosin PF03247.9 KEG12310.1 - 6.6 6.9 21.2 9.3 6.4 8.7 2.3 2 0 0 2 2 2 0 Prothymosin/parathymosin family DUF755 PF05501.6 KEG12310.1 - 7.6 6.6 7.4 15 5.6 5.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) RabGAP-TBC PF00566.13 KEG12311.1 - 5.2e-38 130.6 1.4 1.1e-37 129.6 0.3 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Tom5 PF10642.4 KEG12312.1 - 0.17 11.5 0.3 0.34 10.6 0.2 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase ABC_tran PF00005.22 KEG12313.1 - 8.9e-34 116.7 0.5 3.7e-18 66.1 0.0 3.3 3 0 0 3 3 3 3 ABC transporter AAA_29 PF13555.1 KEG12313.1 - 5.2e-12 45.1 0.4 3.5e-05 23.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 KEG12313.1 - 2.4e-11 44.1 3.4 0.0011 19.0 0.2 4.2 4 0 0 4 4 4 3 AAA domain SMC_N PF02463.14 KEG12313.1 - 7.6e-09 35.1 1.0 0.17 11.0 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 KEG12313.1 - 1.6e-07 30.6 0.0 0.0026 16.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_33 PF13671.1 KEG12313.1 - 6.7e-07 29.2 0.1 0.011 15.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KEG12313.1 - 3.2e-06 27.6 0.0 0.064 13.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KEG12313.1 - 3.3e-06 27.2 2.1 0.13 12.4 0.0 3.3 3 1 0 3 3 3 2 AAA domain Miro PF08477.8 KEG12313.1 - 3.6e-06 27.4 0.1 0.023 15.1 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein FtsK_SpoIIIE PF01580.13 KEG12313.1 - 5.5e-05 22.7 0.1 0.23 10.8 0.1 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_17 PF13207.1 KEG12313.1 - 5.9e-05 23.8 1.3 0.22 12.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 KEG12313.1 - 6.6e-05 22.9 3.6 0.0072 16.3 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain MobB PF03205.9 KEG12313.1 - 6.8e-05 22.6 0.4 0.043 13.5 0.1 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 KEG12313.1 - 9e-05 22.3 0.4 0.44 10.3 0.0 2.3 2 0 0 2 2 2 2 Dynamin family AAA_15 PF13175.1 KEG12313.1 - 0.00011 21.4 0.1 3 6.7 0.0 4.0 4 0 0 4 4 4 0 AAA ATPase domain SRP54 PF00448.17 KEG12313.1 - 0.00011 21.7 0.8 0.02 14.3 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 KEG12313.1 - 0.00015 21.2 0.0 0.17 11.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KEG12313.1 - 0.00043 19.8 0.8 0.34 10.2 0.1 2.6 3 0 0 3 3 3 1 AAA-like domain Zeta_toxin PF06414.7 KEG12313.1 - 0.00054 19.1 0.1 0.39 9.7 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin MMR_HSR1 PF01926.18 KEG12313.1 - 0.00057 19.8 1.2 0.93 9.4 0.0 2.7 2 1 0 2 2 2 2 50S ribosome-binding GTPase Arf PF00025.16 KEG12313.1 - 0.00076 18.7 0.1 0.23 10.7 0.0 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family ATP-synt_ab PF00006.20 KEG12313.1 - 0.0011 18.5 0.0 0.17 11.3 0.0 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.14 KEG12313.1 - 0.0018 17.7 0.5 0.83 9.0 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.15 KEG12313.1 - 0.0029 16.3 0.1 1 7.9 0.0 2.5 2 1 1 3 3 3 1 G-protein alpha subunit AAA_30 PF13604.1 KEG12313.1 - 0.0049 16.4 0.1 0.34 10.4 0.0 2.5 3 0 0 3 3 2 1 AAA domain MutS_V PF00488.16 KEG12313.1 - 0.005 16.2 0.1 3.3 7.0 0.0 3.2 3 0 0 3 3 3 0 MutS domain V AAA_28 PF13521.1 KEG12313.1 - 0.0059 16.5 0.0 2.3 8.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 KEG12313.1 - 0.0076 15.1 0.3 1.1 8.1 0.1 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein NACHT PF05729.7 KEG12313.1 - 0.0085 15.7 7.5 0.11 12.1 0.1 3.6 4 0 0 4 4 4 1 NACHT domain PduV-EutP PF10662.4 KEG12313.1 - 0.0088 15.5 0.1 4.3 6.8 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ArgK PF03308.11 KEG12313.1 - 0.009 14.8 0.2 1.2 7.8 0.0 2.2 2 0 0 2 2 2 1 ArgK protein AAA_19 PF13245.1 KEG12313.1 - 0.0091 15.7 0.7 0.27 11.0 0.2 2.6 2 0 0 2 2 2 1 Part of AAA domain AIG1 PF04548.11 KEG12313.1 - 0.0099 14.9 0.4 0.61 9.1 0.0 2.3 2 0 0 2 2 2 1 AIG1 family AAA_14 PF13173.1 KEG12313.1 - 0.01 15.7 0.9 3.2 7.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain DAP3 PF10236.4 KEG12313.1 - 0.014 14.3 0.5 1.9 7.3 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 DUF815 PF05673.8 KEG12313.1 - 0.015 14.1 0.5 3.1 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA PF00004.24 KEG12313.1 - 0.02 15.0 0.3 8.5 6.5 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KEG12313.1 - 0.02 14.5 0.3 1.8 8.2 0.0 3.0 3 0 0 3 3 3 0 Archaeal ATPase Septin PF00735.13 KEG12313.1 - 0.028 13.4 0.1 4.2 6.3 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_5 PF07728.9 KEG12313.1 - 0.034 13.8 0.1 1.5 8.5 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) VirE PF05272.6 KEG12313.1 - 0.036 13.5 0.0 0.6 9.5 0.0 2.1 2 0 0 2 2 2 0 Virulence-associated protein E DLIC PF05783.6 KEG12313.1 - 0.065 11.9 0.1 0.23 10.0 0.0 1.8 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) IstB_IS21 PF01695.12 KEG12313.1 - 0.065 12.6 0.7 16 4.8 0.0 3.0 4 0 0 4 4 2 0 IstB-like ATP binding protein Sigma54_activat PF00158.21 KEG12313.1 - 0.065 12.7 0.3 18 4.7 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF3584 PF12128.3 KEG12313.1 - 0.09 10.1 3.0 1.4 6.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) ATP_bind_1 PF03029.12 KEG12313.1 - 0.095 12.2 0.9 2.1 7.8 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein APS_kinase PF01583.15 KEG12313.1 - 0.1 12.2 0.3 11 5.6 0.0 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase RNA_helicase PF00910.17 KEG12313.1 - 0.15 12.2 0.1 26 5.0 0.0 2.5 2 0 0 2 2 2 0 RNA helicase SbcCD_C PF13558.1 KEG12313.1 - 0.16 11.9 1.7 2.4 8.1 0.1 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 KEG12313.1 - 0.44 8.9 0.8 6.3 5.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Ribosomal_60s PF00428.14 KEG12314.1 - 0.0033 17.7 5.2 0.16 12.4 0.3 3.2 3 0 0 3 3 3 2 60s Acidic ribosomal protein NRDE-2 PF08424.5 KEG12316.1 - 4.3e-05 22.5 0.5 0.052 12.4 0.1 3.9 3 1 1 4 4 4 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 KEG12316.1 - 0.0086 16.6 0.0 35 5.4 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEG12316.1 - 0.018 15.3 0.0 4.6 7.6 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat MlrC_C PF07171.7 KEG12318.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 MlrC C-terminus AAA_21 PF13304.1 KEG12318.1 - 0.31 10.9 0.1 0.53 10.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain UbiA PF01040.13 KEG12319.1 - 3.8e-27 95.1 18.6 5.2e-27 94.6 12.9 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family V_ATPase_I PF01496.14 KEG12320.1 - 2.3e-214 713.6 13.6 2.7e-213 710.0 9.4 1.9 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family She9_MDM33 PF05546.6 KEG12320.1 - 0.029 13.9 0.4 0.029 13.9 0.3 1.7 2 0 0 2 2 2 0 She9 / Mdm33 family DegS PF05384.6 KEG12320.1 - 5.3 6.2 10.5 18 4.5 0.0 3.4 3 0 0 3 3 3 0 Sensor protein DegS LRR_8 PF13855.1 KEG12322.1 - 7.1e-13 48.1 1.5 0.00031 20.4 1.2 4.4 4 0 0 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 KEG12322.1 - 8.9e-12 44.3 8.9 0.00016 21.2 2.7 4.9 3 2 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEG12322.1 - 3.6e-09 35.3 13.2 0.13 12.3 1.3 6.8 8 0 0 8 8 8 3 Leucine Rich Repeat LRR_6 PF13516.1 KEG12322.1 - 1.7e-06 27.4 5.8 0.12 12.5 0.0 5.2 7 0 0 7 7 7 3 Leucine Rich repeat LRR_7 PF13504.1 KEG12322.1 - 6.4e-05 22.5 17.4 0.24 11.7 0.4 6.1 8 0 0 8 8 8 2 Leucine rich repeat Ala_racemase_N PF01168.15 KEG12323.1 - 2.2e-43 148.3 0.0 2.6e-43 148.0 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain LRR_4 PF12799.2 KEG12324.1 - 5.1e-07 29.1 0.0 0.0032 17.0 0.0 3.1 1 1 4 5 5 5 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 KEG12324.1 - 0.00029 20.4 0.0 0.0006 19.4 0.0 1.4 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 KEG12324.1 - 0.00082 19.0 0.0 0.16 11.7 0.0 2.7 2 1 0 2 2 2 1 Leucine rich repeat HSP90 PF00183.13 KEG12324.1 - 0.075 11.4 4.6 0.099 11.0 3.2 1.1 1 0 0 1 1 1 0 Hsp90 protein DUF2890 PF11081.3 KEG12324.1 - 4 7.4 12.2 5.7 6.9 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) CDC45 PF02724.9 KEG12324.1 - 5.8 4.8 8.3 6.4 4.6 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Sulfate_transp PF00916.15 KEG12325.1 - 6.4e-31 107.4 10.7 6.4e-31 107.4 7.4 2.1 2 1 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KEG12325.1 - 5.2e-16 58.0 3.3 5.2e-16 58.0 2.3 3.3 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KEG12325.1 - 1.7e-06 27.4 0.0 3.6e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 STAS domain TIP41 PF04176.8 KEG12326.1 - 3.3e-21 75.3 0.1 6.8e-21 74.3 0.1 1.5 1 0 0 1 1 1 1 TIP41-like family GAF_2 PF13185.1 KEG12326.1 - 5.4e-06 26.9 0.0 1.2e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 KEG12326.1 - 3.6e-05 23.8 0.0 8e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 KEG12326.1 - 0.00086 19.4 0.0 0.0017 18.5 0.0 1.5 1 0 0 1 1 1 1 GAF domain LicD PF04991.8 KEG12327.1 - 2.7e-18 66.8 0.0 7.7e-17 62.0 0.0 2.2 1 1 0 1 1 1 1 LicD family Kinesin PF00225.18 KEG12328.1 - 7.9e-88 294.3 5.7 1.3e-87 293.6 0.3 3.7 3 1 0 3 3 3 1 Kinesin motor domain DUF948 PF06103.6 KEG12328.1 - 4.2 7.3 13.5 0.19 11.6 0.1 4.1 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Utp11 PF03998.8 KEG12329.1 - 1.2e-49 169.3 16.5 1.2e-49 169.3 11.5 2.0 1 1 1 2 2 2 1 Utp11 protein ABA_WDS PF02496.11 KEG12329.1 - 0.015 15.4 1.7 0.055 13.6 1.2 2.0 1 0 0 1 1 1 0 ABA/WDS induced protein PAS_10 PF13596.1 KEG12329.1 - 0.022 15.0 1.1 0.92 9.8 0.0 3.0 3 0 0 3 3 3 0 PAS domain Chorion_2 PF03964.10 KEG12329.1 - 0.096 13.2 0.7 0.21 12.1 0.2 1.8 2 0 0 2 2 2 0 Chorion family 2 RNA_pol_A_bac PF01000.21 KEG12330.1 - 1.3e-21 76.7 0.0 2.5e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KEG12330.1 - 1.8e-10 39.7 0.0 2.6e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_7 PF12838.2 KEG12330.1 - 0.052 13.9 2.0 0.11 12.9 1.4 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 KEG12330.1 - 0.1 12.8 2.0 0.19 11.9 1.4 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain AAA_19 PF13245.1 KEG12331.1 - 0.00026 20.6 0.3 0.0012 18.5 0.2 2.2 1 0 0 1 1 1 1 Part of AAA domain HA2 PF04408.18 KEG12331.1 - 0.001 19.0 0.0 0.003 17.5 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Surp PF01805.15 KEG12331.1 - 0.062 12.9 0.1 0.17 11.5 0.1 1.8 1 0 0 1 1 1 0 Surp module ANF_receptor PF01094.23 KEG12332.1 - 4.6e-28 98.0 0.9 4.3e-12 45.4 0.0 4.0 3 1 0 3 3 3 3 Receptor family ligand binding region Histone PF00125.19 KEG12333.1 - 1.2e-23 82.9 0.1 2.4e-23 82.0 0.1 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KEG12333.1 - 3.5e-05 23.7 0.0 6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 KEG12333.1 - 0.0022 18.1 0.0 0.0036 17.4 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 KEG12333.1 - 0.0077 15.9 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 KEG12333.1 - 0.015 15.0 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit UPF0179 PF03684.8 KEG12333.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0179) CYTH PF01928.16 KEG12334.1 - 3.3e-12 46.4 3.0 1.9e-08 34.2 0.0 2.8 3 0 0 3 3 3 2 CYTH domain Sensor PF13796.1 KEG12335.1 - 0.055 13.0 2.4 0.071 12.7 1.7 1.1 1 0 0 1 1 1 0 Putative sensor DUF1072 PF06380.6 KEG12335.1 - 0.067 12.8 1.4 0.13 11.9 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1072) Yip1 PF04893.12 KEG12335.1 - 0.081 12.4 0.5 0.094 12.2 0.3 1.1 1 0 0 1 1 1 0 Yip1 domain DUF2909 PF11137.3 KEG12335.1 - 0.09 12.5 3.6 0.1 12.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2909) MHC2-interact PF09307.5 KEG12335.1 - 0.18 11.5 0.5 0.29 10.9 0.3 1.3 1 0 0 1 1 1 0 CLIP, MHC2 interacting Aminotran_4 PF01063.14 KEG12336.1 - 1.4e-21 77.0 0.0 2.1e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class IV Fer4_13 PF13370.1 KEG12336.1 - 0.086 13.2 0.2 0.19 12.1 0.1 1.6 1 0 0 1 1 1 0 4Fe-4S single cluster domain EF-hand_7 PF13499.1 KEG12338.1 - 9.8e-22 76.8 6.9 3.2e-14 52.8 1.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KEG12338.1 - 4.5e-21 72.4 11.4 1.1e-07 30.5 1.2 3.8 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 KEG12338.1 - 5e-20 69.5 5.4 2.5e-06 26.8 0.0 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 KEG12338.1 - 2.4e-16 59.0 11.1 3.8e-13 48.8 1.0 3.8 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 KEG12338.1 - 5.2e-14 50.8 5.5 0.00057 19.0 0.8 3.4 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.1 KEG12338.1 - 5.1e-12 45.5 0.7 8.4e-07 28.8 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KEG12338.1 - 2.1e-05 24.2 0.7 0.062 13.0 0.1 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_like PF09279.6 KEG12338.1 - 0.0025 17.8 5.4 0.49 10.4 0.7 2.5 2 1 0 2 2 2 2 Phosphoinositide-specific phospholipase C, efhand-like DUF3164 PF11363.3 KEG12338.1 - 0.0085 15.5 0.9 0.47 9.8 0.0 2.6 1 1 2 3 3 3 1 Protein of unknown function (DUF3164) MgtE_N PF03448.12 KEG12338.1 - 0.02 15.2 0.8 0.02 15.2 0.5 2.2 3 0 0 3 3 2 0 MgtE intracellular N domain Caleosin PF05042.8 KEG12338.1 - 0.029 13.9 0.1 0.32 10.5 0.0 2.2 2 1 1 3 3 3 0 Caleosin related protein CI-B14_5a PF07347.7 KEG12338.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) TRCF PF03461.10 KEG12338.1 - 0.17 11.8 1.0 2.7 8.0 0.0 2.1 2 0 0 2 2 2 0 TRCF domain LTXXQ PF07813.7 KEG12338.1 - 0.25 11.8 5.9 0.19 12.2 0.6 2.2 1 1 1 2 2 2 0 LTXXQ motif family protein SPARC_Ca_bdg PF10591.4 KEG12338.1 - 0.37 10.8 2.7 2.7 8.0 0.4 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region CBFD_NFYB_HMF PF00808.18 KEG12340.1 - 2.4e-08 33.9 0.1 4.2e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KEG12340.1 - 0.00085 19.3 0.4 0.0015 18.6 0.3 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CDC45 PF02724.9 KEG12340.1 - 0.045 11.8 3.3 0.058 11.4 2.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 KEG12340.1 - 0.066 11.9 12.6 0.1 11.3 8.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.7 KEG12340.1 - 0.53 9.5 8.8 0.76 8.9 6.1 1.3 1 0 0 1 1 1 0 SDA1 FYDLN_acid PF09538.5 KEG12340.1 - 2.7 8.6 15.9 0.54 10.8 8.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF2046 PF09755.4 KEG12341.1 - 1.1e-06 27.7 15.9 1.1e-06 27.7 11.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) Borrelia_REV PF03978.8 KEG12341.1 - 0.014 15.1 1.0 0.049 13.3 0.7 1.9 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein V_ATPase_I PF01496.14 KEG12341.1 - 2.9 5.6 7.8 3.8 5.2 5.4 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sugar_tr PF00083.19 KEG12342.1 - 5.1e-79 265.9 24.3 5.9e-79 265.7 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEG12342.1 - 3.8e-16 58.7 22.4 3.8e-16 58.7 15.6 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 KEG12342.1 - 0.0062 16.5 2.5 0.0062 16.5 1.8 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1228) Paramecium_SA PF01508.11 KEG12342.1 - 0.13 12.4 6.3 1 9.6 1.5 2.4 1 1 1 2 2 2 0 Paramecium surface antigen domain PSI PF01437.20 KEG12342.1 - 0.26 11.4 9.4 1.7 8.8 2.4 2.5 1 1 1 2 2 2 0 Plexin repeat tRNA-synt_2 PF00152.15 KEG12344.1 - 5.1e-72 242.4 0.0 8.2e-72 241.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_synt_1c_R1 PF04558.10 KEG12344.1 - 3.7e-40 137.1 0.1 6.6e-40 136.3 0.1 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_anti-codon PF01336.20 KEG12344.1 - 6.3e-10 38.7 0.0 1.2e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Clat_adaptor_s PF01217.15 KEG12345.1 - 6.7e-49 165.2 4.2 7.4e-49 165.1 2.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain MMgT PF10270.4 KEG12346.1 - 0.13 12.7 5.2 1.2 9.5 3.6 2.4 1 1 0 1 1 1 0 Membrane magnesium transporter Cofilin_ADF PF00241.15 KEG12349.1 - 8.5e-14 51.5 0.0 1.7e-09 37.6 0.0 2.3 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein TPR_12 PF13424.1 KEG12350.1 - 2.1e-05 24.3 2.3 0.07 13.0 1.8 3.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEG12350.1 - 0.0082 15.9 7.1 0.97 9.5 0.0 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 KEG12350.1 - 0.016 15.6 2.7 64 4.3 0.4 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3161 PF11362.3 KEG12350.1 - 0.13 12.1 0.1 1.2 9.0 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3161) TPR_14 PF13428.1 KEG12350.1 - 1.4 9.7 10.8 21 6.1 1.8 4.3 4 2 1 5 5 5 0 Tetratricopeptide repeat Glyco_transf_18 PF15024.1 KEG12351.1 - 0.05 11.9 0.0 0.054 11.8 0.0 1.0 1 0 0 1 1 1 0 Glycosyltransferase family 18 Rhabdo_M2 PF04785.7 KEG12352.1 - 0.051 12.6 0.2 0.083 11.9 0.1 1.3 1 0 0 1 1 1 0 Rhabdovirus matrix protein M2 Dak1 PF02733.12 KEG12353.1 - 2.1e-82 276.2 1.0 3.3e-82 275.6 0.7 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 KEG12353.1 - 1.2e-40 139.0 4.0 2.2e-40 138.1 2.8 1.5 1 0 0 1 1 1 1 DAK2 domain PARP_regulatory PF01358.13 KEG12354.1 - 5e-19 68.0 0.0 2.4e-12 46.0 0.0 2.5 2 1 0 2 2 2 2 Poly A polymerase regulatory subunit DUF2428 PF10350.4 KEG12357.1 - 4e-57 193.1 0.0 1e-56 191.8 0.0 1.8 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) TP_methylase PF00590.15 KEG12358.1 - 9.2e-20 71.2 0.4 3.2e-19 69.4 0.3 1.9 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases 6PGD PF00393.14 KEG12359.1 - 3.8e-88 295.4 0.0 5.2e-88 295.0 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KEG12359.1 - 1.9e-45 154.6 0.9 3.5e-45 153.7 0.6 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 KEG12359.1 - 5.4e-05 23.3 0.4 0.00013 22.0 0.3 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 KEG12359.1 - 9.6e-05 22.1 2.0 0.0001 21.9 0.1 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KEG12359.1 - 0.00028 21.2 0.6 0.00058 20.2 0.4 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.19 KEG12359.1 - 0.0045 15.9 0.0 0.0073 15.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_11 PF14833.1 KEG12359.1 - 0.0054 16.7 0.1 0.016 15.2 0.0 2.0 1 1 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.14 KEG12359.1 - 0.0071 15.5 0.2 0.013 14.6 0.2 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 KEG12359.1 - 0.012 15.1 0.1 0.022 14.2 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 KEG12359.1 - 0.016 14.9 0.1 0.034 13.8 0.1 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GFO_IDH_MocA PF01408.17 KEG12359.1 - 0.062 13.8 0.1 0.15 12.5 0.1 1.7 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DUF2235 PF09994.4 KEG12359.1 - 0.13 11.6 0.0 0.29 10.4 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Pyr_redox_2 PF07992.9 KEG12359.1 - 0.13 12.0 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 KEG12359.1 - 0.14 11.5 0.1 0.29 10.4 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Mito_carr PF00153.22 KEG12360.1 - 2.4e-57 190.6 1.6 2.3e-22 78.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein TRAPP PF04051.11 KEG12361.1 - 8.7e-25 87.0 0.0 1e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Dynamitin PF04912.9 KEG12361.1 - 0.056 12.2 0.0 0.069 11.9 0.0 1.1 1 0 0 1 1 1 0 Dynamitin LRR_4 PF12799.2 KEG12364.1 - 6.3e-09 35.2 9.1 1.2e-05 24.7 1.6 3.2 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG12364.1 - 8.8e-08 31.7 12.2 7.6e-05 22.3 0.6 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_9 PF14580.1 KEG12364.1 - 7.5e-07 28.8 0.7 1.6e-06 27.8 0.5 1.5 1 1 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.1 KEG12364.1 - 0.00026 20.7 1.2 1 9.6 0.3 4.4 3 1 1 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.28 KEG12364.1 - 0.089 12.8 7.2 14 6.2 0.6 4.1 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_7 PF13504.1 KEG12364.1 - 0.092 12.9 6.7 8.8 7.0 0.4 4.7 5 1 0 5 5 5 0 Leucine rich repeat LRR_4 PF12799.2 KEG12365.1 - 3.5e-33 112.6 0.0 0.0028 17.2 0.0 9.2 3 1 4 9 9 9 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG12365.1 - 8e-25 86.3 0.0 0.0015 18.2 0.0 6.7 5 1 2 7 7 7 7 Leucine rich repeat LRR_6 PF13516.1 KEG12365.1 - 1.7e-20 70.7 0.2 0.018 15.0 0.0 9.9 10 1 0 10 10 10 4 Leucine Rich repeat LRR_1 PF00560.28 KEG12365.1 - 1.4e-11 42.7 6.2 18 5.8 0.0 11.8 12 2 1 13 13 13 2 Leucine Rich Repeat LRR_7 PF13504.1 KEG12365.1 - 0.00076 19.2 14.8 1.1e+02 3.7 0.0 10.5 8 3 1 9 9 9 0 Leucine rich repeat NMU PF02070.10 KEG12365.1 - 0.034 13.6 0.2 29 4.3 0.0 4.0 5 0 0 5 5 5 0 Neuromedin U TetR_C_2 PF08361.6 KEG12365.1 - 0.041 13.7 0.0 44 4.0 0.0 3.7 4 0 0 4 4 4 0 MAATS-type transcriptional repressor, C-terminal region LRR_4 PF12799.2 KEG12366.1 - 1e-27 95.2 0.0 0.00055 19.4 0.2 9.4 2 2 6 9 9 9 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG12366.1 - 8.5e-19 67.0 3.2 0.0032 17.1 0.0 6.5 3 2 6 9 9 9 6 Leucine rich repeat LRR_1 PF00560.28 KEG12366.1 - 2.7e-11 41.8 3.6 2.2 8.6 0.2 10.6 9 3 1 10 10 10 2 Leucine Rich Repeat LRR_6 PF13516.1 KEG12366.1 - 8.6e-09 34.5 2.6 6.6 7.1 0.0 8.3 8 1 0 8 8 8 2 Leucine Rich repeat LRR_7 PF13504.1 KEG12366.1 - 0.0033 17.3 13.8 5.6 7.6 0.4 9.4 6 3 2 8 8 8 1 Leucine rich repeat HEAT_2 PF13646.1 KEG12368.1 - 2.2e-07 31.0 1.5 0.85 9.9 0.0 5.8 4 1 1 5 5 5 3 HEAT repeats HEAT PF02985.17 KEG12368.1 - 0.0078 16.2 18.6 27 5.2 0.1 8.6 10 0 0 10 10 10 1 HEAT repeat Adaptin_N PF01602.15 KEG12368.1 - 0.047 12.0 2.9 0.059 11.6 0.4 2.3 2 0 0 2 2 2 0 Adaptin N terminal region Cnd1 PF12717.2 KEG12368.1 - 0.13 12.0 2.0 4.1 7.2 0.1 3.9 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 IF-2B PF01008.12 KEG12369.1 - 1.1e-21 77.0 1.4 5.2e-19 68.3 1.0 3.2 1 1 0 1 1 1 1 Initiation factor 2 subunit family HAUS4 PF14735.1 KEG12369.1 - 0.032 13.5 0.1 0.045 13.0 0.1 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 DUF465 PF04325.8 KEG12369.1 - 0.19 11.4 1.8 9.4 6.0 0.0 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF465) PITH PF06201.8 KEG12370.1 - 1.2e-34 119.3 0.0 1.4e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 PITH domain Proteasome PF00227.21 KEG12371.1 - 1.2e-43 148.5 0.9 1.6e-43 148.2 0.6 1.1 1 0 0 1 1 1 1 Proteasome subunit DAP3 PF10236.4 KEG12372.1 - 4.1e-27 94.9 0.0 6e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.7 KEG12372.1 - 0.0081 15.8 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 KEG12372.1 - 0.018 14.7 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 KEG12372.1 - 0.053 13.6 0.0 0.19 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KEG12372.1 - 0.059 13.0 0.0 0.13 11.9 0.0 1.5 2 0 0 2 2 2 0 Archaeal ATPase AAA_10 PF12846.2 KEG12372.1 - 0.073 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain RNA_helicase PF00910.17 KEG12372.1 - 0.099 12.8 0.0 2.1 8.5 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.1 KEG12372.1 - 0.14 12.0 0.0 3.9 7.3 0.0 2.4 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.1 KEG12372.1 - 0.15 12.0 0.0 0.32 10.9 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.12 KEG12372.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Metallophos PF00149.23 KEG12374.1 - 0.00015 21.2 0.0 0.00061 19.2 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3024 PF11225.3 KEG12376.1 - 0.036 13.9 1.7 15 5.5 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3024) TPR_4 PF07721.9 KEG12377.1 - 0.023 15.0 0.8 0.26 11.8 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEG12377.1 - 0.21 12.3 7.0 0.36 11.6 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 KEG12377.1 - 1.1 9.9 6.6 1.4 9.7 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DNA_ligase_A_M PF01068.16 KEG12378.1 - 1.6e-06 27.6 0.0 2e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_M PF01068.16 KEG12379.1 - 1.4e-07 31.1 0.0 1.6e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.10 KEG12380.1 - 4.1e-09 36.7 0.0 6.1e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 KEG12381.1 - 0.054 13.6 0.4 3 8.0 0.0 2.8 2 1 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain RelB_N PF12910.2 KEG12381.1 - 0.067 12.5 0.1 0.13 11.6 0.1 1.5 1 0 0 1 1 1 0 Antitoxin of toxin-antitoxin stability system N-terminal Reo_sigmaC PF04582.7 KEG12383.1 - 0.00027 20.2 40.5 0.017 14.2 3.7 6.2 2 1 6 8 8 8 6 Reovirus sigma C capsid protein Bacillus_HBL PF05791.6 KEG12383.1 - 0.0017 17.7 0.6 0.0017 17.7 0.4 8.5 5 3 4 10 10 10 3 Bacillus haemolytic enterotoxin (HBL) Arf PF00025.16 KEG12385.1 - 5.1e-58 195.1 0.0 5.8e-58 194.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 KEG12385.1 - 3.1e-09 37.3 0.0 4e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 KEG12385.1 - 1.8e-08 33.4 0.5 7.8e-06 24.8 0.0 2.5 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 KEG12385.1 - 1.9e-08 33.7 0.0 2.5e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 KEG12385.1 - 2.8e-08 33.3 0.0 3.2e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 KEG12385.1 - 3.5e-07 30.1 0.0 5.3e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KEG12385.1 - 1.8e-06 27.5 0.2 0.00067 19.1 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KEG12385.1 - 6.1e-05 22.2 0.0 6.8e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 KEG12385.1 - 0.00089 18.5 0.0 0.0078 15.5 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B cobW PF02492.14 KEG12385.1 - 0.0031 17.0 0.0 0.21 11.0 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 KEG12385.1 - 0.027 13.9 0.0 0.058 12.8 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.17 KEG12385.1 - 0.03 13.7 0.1 0.054 12.9 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_28 PF13521.1 KEG12385.1 - 0.04 13.8 0.1 0.44 10.4 0.0 2.0 1 1 0 2 2 2 0 AAA domain Tubulin_C PF03953.12 KEG12388.1 - 0.052 13.5 0.3 0.17 11.8 0.2 1.9 1 0 0 1 1 1 0 Tubulin C-terminal domain Baculo_PEP_C PF04513.7 KEG12388.1 - 0.13 12.0 6.1 0.26 11.0 0.3 3.9 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus CCDC92 PF14916.1 KEG12388.1 - 0.25 10.9 11.7 0.22 11.1 1.6 3.6 3 0 0 3 3 3 0 Coiled-coil domain of unknown function WD40_alt PF14077.1 KEG12388.1 - 0.44 10.2 8.0 2.2 7.9 0.1 3.8 3 0 0 3 3 3 0 Alternative WD40 repeat motif Vault PF01505.13 KEG12389.1 - 2.9e-53 177.6 7.5 6.9e-12 45.2 0.1 6.0 5 0 0 5 5 5 5 Major Vault Protein repeat MVP_shoulder PF11978.3 KEG12389.1 - 3.4e-51 172.0 0.1 7.7e-51 170.9 0.1 1.7 1 0 0 1 1 1 1 Shoulder domain DUF3601 PF12208.3 KEG12389.1 - 0.033 14.1 0.0 5.3 7.0 0.0 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF3601) Lipocalin_2 PF08212.7 KEG12389.1 - 0.047 13.4 0.1 0.089 12.5 0.1 1.4 1 0 0 1 1 1 0 Lipocalin-like domain DUF4642 PF15484.1 KEG12390.1 - 0.02 14.8 1.1 0.028 14.3 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4642) DUF2457 PF10446.4 KEG12390.1 - 0.028 13.1 16.1 0.034 12.9 11.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop53 PF07767.6 KEG12390.1 - 0.071 12.0 2.0 0.08 11.9 1.4 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Pox_RNA_Pol_19 PF05320.7 KEG12390.1 - 0.081 12.6 1.3 0.1 12.3 0.9 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit CDC45 PF02724.9 KEG12390.1 - 0.14 10.1 7.1 0.16 9.9 5.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Voldacs PF03517.8 KEG12390.1 - 0.18 11.6 7.1 1.2 9.0 4.9 1.9 1 1 1 2 2 2 0 Regulator of volume decrease after cellular swelling Myc_N PF01056.13 KEG12390.1 - 0.39 9.8 4.9 0.46 9.6 3.4 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Nucleoplasmin PF03066.10 KEG12390.1 - 0.41 10.1 13.9 0.65 9.5 9.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin TFIIF_alpha PF05793.7 KEG12390.1 - 0.5 8.6 11.5 0.56 8.5 8.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Spt5_N PF11942.3 KEG12390.1 - 1.5 9.4 17.9 3.7 8.2 12.4 1.8 1 1 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal SDA1 PF05285.7 KEG12390.1 - 2.4 7.3 13.3 2.8 7.1 9.2 1.1 1 0 0 1 1 1 0 SDA1 RXT2_N PF08595.6 KEG12390.1 - 4 7.2 9.1 8 6.2 6.3 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal ATG27 PF09451.5 KEG12390.1 - 5.5 6.1 6.4 7.4 5.7 4.4 1.1 1 0 0 1 1 1 0 Autophagy-related protein 27 Dynein_light PF01221.13 KEG12391.1 - 1e-32 111.9 1.5 1e-32 111.9 1.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Vasohibin PF14822.1 KEG12391.1 - 0.0034 16.5 0.1 0.0037 16.3 0.1 1.2 1 0 0 1 1 1 1 Vasohibin Pkinase PF00069.20 KEG12392.1 - 9.5e-54 182.2 0.0 1.4e-53 181.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG12392.1 - 2.1e-24 85.9 0.0 2.2e-20 72.8 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KEG12392.1 - 9.6e-05 22.2 1.0 0.00023 21.0 0.1 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KEG12392.1 - 0.01 14.8 0.0 1.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.17 KEG12392.1 - 0.012 14.9 0.1 0.035 13.4 0.1 1.7 1 1 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.4 KEG12392.1 - 0.071 12.4 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 KEG12392.1 - 0.09 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DEAD PF00270.24 KEG12393.1 - 7.3e-43 145.9 0.0 1.4e-41 141.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase GUCT PF08152.7 KEG12393.1 - 7.9e-26 89.8 0.0 1.9e-25 88.6 0.0 1.7 1 0 0 1 1 1 1 GUCT (NUC152) domain Helicase_C PF00271.26 KEG12393.1 - 4.3e-24 84.1 0.0 1.2e-23 82.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEG12393.1 - 0.0049 16.7 0.2 0.097 12.4 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Rrp15p PF07890.7 KEG12394.1 - 1.7e-05 24.8 18.7 6.6e-05 22.9 13.0 1.9 1 1 0 1 1 1 1 Rrp15p LRR_6 PF13516.1 KEG12395.1 - 1.1e-26 89.8 11.6 0.012 15.5 0.0 9.8 10 0 0 10 10 10 7 Leucine Rich repeat LRR_4 PF12799.2 KEG12395.1 - 3e-09 36.2 1.5 0.065 12.8 0.0 5.6 5 1 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEG12395.1 - 7.4e-06 25.3 6.4 12 6.3 0.0 6.9 7 1 0 7 7 7 2 Leucine Rich Repeat LRR_8 PF13855.1 KEG12395.1 - 8e-05 22.3 4.7 5.6 6.7 0.0 5.8 5 1 1 6 6 6 2 Leucine rich repeat LRR_7 PF13504.1 KEG12395.1 - 0.0084 16.1 7.5 21 5.9 0.0 6.7 7 0 0 7 7 7 1 Leucine rich repeat Metallophos PF00149.23 KEG12397.1 - 1.6e-29 102.7 0.2 2.5e-29 102.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KEG12397.1 - 0.00024 20.9 0.0 0.00041 20.2 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Big_4 PF07532.6 KEG12399.1 - 0.03 13.8 0.0 0.063 12.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 4) Macro PF01661.16 KEG12400.1 - 1.2e-06 28.3 0.0 2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Macro domain DUF202 PF02656.10 KEG12400.1 - 0.011 15.9 0.1 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF202) ECH_C PF13766.1 KEG12401.1 - 3.3e-09 36.8 0.0 1.7e-05 24.9 0.0 3.7 3 0 0 3 3 3 2 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 KEG12401.1 - 1e-06 28.0 0.0 3.5e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family Peptidase_S8 PF00082.17 KEG12401.1 - 0.017 14.2 0.8 0.029 13.5 0.5 1.3 1 0 0 1 1 1 0 Subtilase family Ribosomal_L22e PF01776.12 KEG12402.1 - 1.2e-40 137.9 2.6 1.5e-40 137.6 1.8 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF2972 PF11186.3 KEG12402.1 - 0.019 14.8 0.9 0.024 14.5 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) Asparaginase PF00710.15 KEG12403.1 - 9.8e-73 244.7 0.0 1.2e-72 244.5 0.0 1.0 1 0 0 1 1 1 1 Asparaginase zf-B_box PF00643.19 KEG12404.1 - 0.0061 16.4 3.6 0.049 13.5 0.2 2.5 2 0 0 2 2 2 1 B-box zinc finger Stanniocalcin PF03298.8 KEG12404.1 - 0.032 13.2 0.0 0.062 12.3 0.0 1.4 1 0 0 1 1 1 0 Stanniocalcin family NOB1_Zn_bind PF08772.6 KEG12404.1 - 0.25 11.1 6.8 0.081 12.7 0.5 2.7 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like Lar_restr_allev PF14354.1 KEG12404.1 - 0.41 10.9 1.9 1.3 9.3 0.1 2.4 2 0 0 2 2 2 0 Restriction alleviation protein Lar IFT57 PF10498.4 KEG12404.1 - 2.7 6.6 7.2 0.27 9.9 0.2 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 IncA PF04156.9 KEG12404.1 - 3.5 7.1 8.3 1.4 8.5 0.4 2.2 2 0 0 2 2 2 0 IncA protein TPR_17 PF13431.1 KEG12405.1 - 1.7e-09 37.1 2.9 0.0012 18.8 0.1 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEG12405.1 - 1.5e-07 31.6 0.1 0.0011 19.2 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KEG12405.1 - 4.4e-07 29.4 2.5 9.7e-05 21.9 0.0 3.9 4 0 0 4 4 4 1 TPR repeat TPR_14 PF13428.1 KEG12405.1 - 8e-07 29.1 0.2 0.068 13.8 0.1 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEG12405.1 - 1.3e-05 24.7 0.6 0.00072 19.2 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEG12405.1 - 3.3e-05 23.3 0.0 0.007 16.0 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEG12405.1 - 0.00014 22.4 0.1 0.019 15.6 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 KEG12405.1 - 0.00041 20.4 0.9 0.0059 16.7 0.0 2.6 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KEG12405.1 - 0.0011 18.8 0.2 0.095 12.6 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_20 PF14561.1 KEG12405.1 - 0.0012 18.8 0.1 0.048 13.7 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEG12405.1 - 0.0017 17.9 0.4 0.037 13.6 0.2 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 KEG12405.1 - 0.024 15.0 1.5 0.18 12.3 0.0 3.2 4 0 0 4 4 3 0 Tetratricopeptide repeat BTAD PF03704.12 KEG12405.1 - 0.04 14.2 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Bacterial transcriptional activator domain TPR_8 PF13181.1 KEG12405.1 - 0.078 12.7 0.1 0.27 11.0 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Peptidase_M3 PF01432.15 KEG12406.1 - 2.6e-75 254.2 0.2 3.2e-74 250.6 0.1 2.0 1 1 0 1 1 1 1 Peptidase family M3 UCR_Fe-S_N PF10399.4 KEG12407.1 - 0.00048 19.2 6.1 0.00074 18.6 4.2 1.3 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal CytB6-F_Fe-S PF08802.5 KEG12407.1 - 0.19 11.7 1.7 0.31 11.0 1.1 1.4 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit TAT_signal PF10518.4 KEG12407.1 - 4 7.6 11.8 6.7 6.9 8.1 1.4 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence DnaJ PF00226.26 KEG12408.1 - 3.5e-23 81.1 0.1 7.7e-23 80.0 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Fib_alpha PF08702.5 KEG12408.1 - 0.029 14.4 0.1 0.08 13.0 0.1 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Terminase_6 PF03237.10 KEG12408.1 - 0.03 13.0 0.0 0.045 12.5 0.0 1.2 1 0 0 1 1 1 0 Terminase-like family E2F_TDP PF02319.15 KEG12408.1 - 0.079 12.5 0.1 0.77 9.3 0.0 2.4 2 0 0 2 2 2 0 E2F/DP family winged-helix DNA-binding domain Aa_trans PF01490.13 KEG12409.1 - 1.3e-37 129.2 18.4 3.5e-33 114.6 5.1 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Methyltransf_26 PF13659.1 KEG12410.1 - 2.9e-14 53.0 0.0 5.6e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEG12410.1 - 2e-13 50.1 0.0 1.8e-11 43.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.1 KEG12410.1 - 1.3e-12 47.6 0.0 1.3e-11 44.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEG12410.1 - 3.2e-10 40.5 0.0 8.2e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KEG12410.1 - 3.8e-08 32.8 0.2 1.4e-07 30.9 0.1 1.9 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 KEG12410.1 - 1.5e-06 28.5 0.0 3.7e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KEG12410.1 - 3.5e-06 26.5 0.2 9.2e-06 25.2 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_15 PF09445.5 KEG12410.1 - 8.2e-06 25.4 0.0 2.9e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.11 KEG12410.1 - 1.2e-05 25.0 0.0 1.8e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.13 KEG12410.1 - 6.5e-05 22.5 0.2 0.0012 18.4 0.2 2.4 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.7 KEG12410.1 - 6.8e-05 23.2 0.0 0.00018 21.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 KEG12410.1 - 0.00022 20.6 0.1 0.014 14.7 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Ubie_methyltran PF01209.13 KEG12410.1 - 0.0004 19.5 0.0 0.001 18.2 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 KEG12410.1 - 0.00041 20.7 0.0 0.0018 18.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 KEG12410.1 - 0.00087 18.3 0.0 0.0016 17.5 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 KEG12410.1 - 0.0077 15.9 0.0 0.022 14.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 KEG12410.1 - 0.011 14.4 0.0 0.023 13.3 0.0 1.4 2 0 0 2 2 2 0 tRNA (Uracil-5-)-methyltransferase TRM PF02005.11 KEG12410.1 - 0.013 14.4 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase N6_Mtase PF02384.11 KEG12410.1 - 0.016 14.2 0.0 0.031 13.3 0.0 1.4 1 1 0 1 1 1 0 N-6 DNA Methylase Methyltransf_32 PF13679.1 KEG12410.1 - 0.027 14.1 0.1 0.074 12.7 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Eco57I PF07669.6 KEG12410.1 - 0.085 13.2 0.0 0.24 11.7 0.0 1.8 1 0 0 1 1 1 0 Eco57I restriction-modification methylase DUF2870 PF11069.3 KEG12411.1 - 2.8e-39 133.0 0.0 6.4e-39 131.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) Enterotoxin_b PF01376.13 KEG12411.1 - 0.092 12.6 0.0 0.28 11.0 0.0 1.8 1 0 0 1 1 1 0 Heat-labile enterotoxin beta chain PgaD PF13994.1 KEG12412.1 - 0.028 13.8 0.1 0.032 13.6 0.1 1.1 1 0 0 1 1 1 0 PgaD-like protein DUF1077 PF06417.7 KEG12413.1 - 6e-43 145.1 1.4 7.2e-43 144.9 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) ELO PF01151.13 KEG12414.1 - 0.055 12.7 0.1 0.065 12.5 0.1 1.0 1 0 0 1 1 1 0 GNS1/SUR4 family Actin PF00022.14 KEG12416.1 - 0.0016 16.9 0.1 0.0028 16.1 0.0 1.3 1 0 0 1 1 1 1 Actin MSC PF09402.5 KEG12417.1 - 0.051 12.2 0.0 0.069 11.8 0.0 1.1 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain RRM_1 PF00076.17 KEG12418.1 - 8.1e-33 111.8 0.0 2.7e-10 39.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG12418.1 - 1.8e-24 85.4 0.1 4.8e-09 36.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG12418.1 - 1.9e-19 69.2 0.1 1.5e-06 27.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KEG12418.1 - 0.007 16.1 0.1 2 8.2 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif DREV PF05219.7 KEG12419.1 - 3.2e-59 199.9 0.0 3.8e-59 199.7 0.0 1.0 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_23 PF13489.1 KEG12419.1 - 1.1e-09 38.2 0.0 1.6e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEG12419.1 - 3.5e-07 30.6 0.0 2.5e-06 27.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEG12419.1 - 2.3e-05 24.9 0.0 0.00052 20.5 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEG12419.1 - 0.0007 20.0 0.0 0.002 18.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 KEG12419.1 - 0.0052 15.8 0.0 0.0082 15.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_31 PF13847.1 KEG12419.1 - 0.021 14.4 0.0 0.88 9.1 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain IQ PF00612.22 KEG12421.1 - 3.4e-06 26.2 20.4 0.0013 18.1 0.7 5.6 5 0 0 5 5 5 4 IQ calmodulin-binding motif Sdh5 PF03937.11 KEG12422.1 - 2.5e-23 81.5 0.2 3.9e-23 80.9 0.1 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase RF-1 PF00472.15 KEG12423.1 - 2.9e-14 52.8 0.1 5e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.4 KEG12423.1 - 0.0042 17.1 0.0 0.0066 16.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Corona_S2 PF01601.11 KEG12425.1 - 0.069 11.2 6.5 0.14 10.2 4.5 1.4 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein DUF1042 PF06294.6 KEG12426.1 - 8.6e-14 51.4 0.0 2e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1042) CAMSAP_CH PF11971.3 KEG12426.1 - 0.0031 17.1 0.0 0.0077 15.8 0.0 1.7 1 0 0 1 1 1 1 CAMSAP CH domain Peptidase_M24 PF00557.19 KEG12427.1 - 2.5e-43 148.0 0.1 3.2e-43 147.7 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 KEG12427.1 - 3.3e-05 23.6 4.6 7.3e-05 22.5 3.2 1.6 1 0 0 1 1 1 1 MYND finger IR1-M PF12185.3 KEG12427.1 - 0.3 10.8 2.4 0.8 9.4 1.7 1.6 1 0 0 1 1 1 0 Nup358/RanBP2 E3 ligase domain LRR_4 PF12799.2 KEG12428.1 - 7.9e-08 31.7 4.3 0.0024 17.4 0.0 3.6 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) Arrestin_N PF00339.24 KEG12428.1 - 0.11 12.2 0.1 0.27 11.0 0.0 1.6 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain IQ PF00612.22 KEG12429.1 - 2.7 7.8 31.8 0.37 10.5 1.4 5.8 5 0 0 5 5 5 0 IQ calmodulin-binding motif Arginase PF00491.16 KEG12430.1 - 1.4e-53 181.9 0.0 1.6e-53 181.7 0.0 1.0 1 0 0 1 1 1 1 Arginase family WAP PF00095.16 KEG12431.1 - 0.024 14.6 0.5 0.036 14.0 0.4 1.3 1 0 0 1 1 1 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' LLC1 PF14945.1 KEG12431.1 - 0.1 12.8 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein DUF904 PF06005.7 KEG12433.1 - 0.054 13.7 3.1 0.47 10.7 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF4140 PF13600.1 KEG12433.1 - 0.18 12.2 1.5 2.1 8.8 0.1 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) bZIP_1 PF00170.16 KEG12433.1 - 1.4 8.9 7.6 0.084 12.8 1.3 1.9 2 0 0 2 2 2 0 bZIP transcription factor HALZ PF02183.13 KEG12433.1 - 2.3 7.9 9.1 0.3 10.8 2.7 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper FadA PF09403.5 KEG12433.1 - 4.2 7.3 6.3 5.9 6.9 0.9 2.8 3 0 0 3 3 3 0 Adhesion protein FadA Cons_hypoth698 PF03601.9 KEG12434.1 - 0.045 12.4 0.0 0.063 11.9 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 698 FtsX PF02687.16 KEG12434.1 - 0.071 12.8 1.5 1.1 9.0 2.1 1.8 1 1 1 2 2 2 0 FtsX-like permease family Rap1-DNA-bind PF09197.5 KEG12435.1 - 0.0017 18.8 0.1 0.007 16.9 0.0 1.9 2 0 0 2 2 2 1 Rap1, DNA-binding DUF2360 PF10152.4 KEG12436.1 - 3.8e-16 59.6 0.0 4.4e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) Adaptin_N PF01602.15 KEG12437.1 - 5.8e-73 245.9 14.1 7.8e-73 245.5 9.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 KEG12437.1 - 1.7e-35 122.0 0.1 4.4e-35 120.7 0.1 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Cnd1 PF12717.2 KEG12437.1 - 0.029 14.2 7.7 0.73 9.6 0.1 4.3 3 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KEG12437.1 - 0.28 11.3 7.5 6.8 7.0 0.0 4.9 5 0 0 5 5 5 0 HEAT repeat IQ PF00612.22 KEG12438.1 - 1.6e-21 73.8 106.4 0.0059 16.1 3.3 17.5 16 1 1 17 17 17 15 IQ calmodulin-binding motif ADP_ribosyl_GH PF03747.9 KEG12441.1 - 5e-12 46.1 0.4 7.3e-08 32.5 0.0 2.9 2 1 0 3 3 3 2 ADP-ribosylglycohydrolase LRR_4 PF12799.2 KEG12442.1 - 2.8e-18 65.1 3.6 5.6e-07 29.0 0.1 4.5 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) IQ PF00612.22 KEG12442.1 - 6e-12 44.0 14.3 7e-05 22.1 0.5 4.0 3 0 0 3 3 3 3 IQ calmodulin-binding motif LRR_8 PF13855.1 KEG12442.1 - 1.9e-09 37.1 7.7 0.00072 19.2 0.0 4.1 3 1 1 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 KEG12442.1 - 6.5e-06 25.4 12.5 4.3 7.7 0.0 7.4 6 1 1 7 7 7 2 Leucine Rich Repeat LRR_9 PF14580.1 KEG12442.1 - 1.4e-05 24.7 0.1 0.0029 17.1 0.0 2.6 2 0 0 2 2 2 1 Leucine-rich repeat LRR_7 PF13504.1 KEG12442.1 - 0.00025 20.7 11.7 18 6.0 0.0 7.4 6 1 0 6 6 6 0 Leucine rich repeat LRR_6 PF13516.1 KEG12442.1 - 0.0058 16.5 9.7 32 5.0 0.0 6.5 5 2 2 7 7 7 0 Leucine Rich repeat DUF1515 PF07439.6 KEG12442.1 - 0.064 13.0 0.2 1 9.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Asp_decarbox PF02261.11 KEG12442.1 - 0.12 11.9 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Aspartate decarboxylase HEAT_2 PF13646.1 KEG12443.1 - 1e-10 41.7 12.0 0.25 11.6 0.1 7.0 3 1 3 7 7 7 4 HEAT repeats HEAT_EZ PF13513.1 KEG12443.1 - 8.7e-10 38.7 5.0 0.02 15.3 0.3 7.5 6 1 2 8 8 8 2 HEAT-like repeat SF3b1 PF08920.5 KEG12443.1 - 7.2e-09 35.8 8.4 4.2e-06 26.8 5.8 2.9 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 CTD PF12815.2 KEG12443.1 - 3.6e-08 33.8 14.9 3.6e-08 33.8 10.3 2.5 1 1 1 2 2 2 1 Spt5 C-terminal nonapeptide repeat binding Spt4 HEAT PF02985.17 KEG12443.1 - 0.00016 21.5 10.8 2.6 8.3 0.1 7.9 8 1 0 8 8 8 1 HEAT repeat MMS19_C PF12460.3 KEG12443.1 - 0.00097 17.9 0.5 0.67 8.6 0.0 3.9 3 1 0 3 3 3 1 RNAPII transcription regulator C-terminal Arm PF00514.18 KEG12443.1 - 0.019 14.7 0.4 6.5 6.7 0.0 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat M11L PF11099.3 KEG12443.1 - 0.11 12.2 0.3 0.84 9.3 0.0 2.5 3 0 0 3 3 3 0 Apoptosis regulator M11L like Ribosomal_S17e PF00833.13 KEG12445.1 - 2.4e-52 175.8 2.7 2.7e-52 175.6 1.9 1.0 1 0 0 1 1 1 1 Ribosomal S17 HEAT_2 PF13646.1 KEG12446.1 - 3.1e-15 56.2 17.1 0.00011 22.4 0.0 5.2 4 0 0 4 4 4 3 HEAT repeats HEAT PF02985.17 KEG12446.1 - 1.8e-05 24.3 15.1 0.013 15.5 0.0 6.5 8 0 0 8 8 8 2 HEAT repeat DUF2668 PF10873.3 KEG12446.1 - 0.00039 20.6 0.1 0.0016 18.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2668) HEAT_EZ PF13513.1 KEG12446.1 - 1.7 9.2 27.6 2.3 8.8 0.8 7.6 5 2 2 7 7 7 0 HEAT-like repeat Secretin_N_2 PF07655.8 KEG12446.1 - 3.8 7.9 10.3 2 8.8 3.3 2.9 2 0 0 2 2 2 0 Secretin N-terminal domain PIF1 PF05970.9 KEG12447.1 - 1.1e-30 106.8 0.2 1.2e-26 93.5 0.0 3.0 2 1 1 3 3 3 2 PIF1-like helicase AAA_30 PF13604.1 KEG12447.1 - 5.5e-13 48.9 0.0 1e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEG12447.1 - 8.7e-05 22.1 1.1 0.00034 20.3 0.7 2.0 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 KEG12447.1 - 0.00044 19.8 0.0 0.21 11.0 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 KEG12447.1 - 0.0008 19.5 0.0 0.0027 17.8 0.0 2.0 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 KEG12447.1 - 0.003 17.6 0.1 0.011 15.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 KEG12447.1 - 0.0088 15.7 0.1 0.017 14.7 0.1 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 KEG12447.1 - 0.011 14.6 0.0 0.022 13.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein UvrD-helicase PF00580.16 KEG12447.1 - 0.018 14.3 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA PF00004.24 KEG12447.1 - 0.023 14.8 0.1 0.067 13.4 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 KEG12447.1 - 0.025 13.5 0.5 0.069 12.1 0.3 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 KEG12447.1 - 0.044 13.7 0.1 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_11 PF13086.1 KEG12447.1 - 0.051 13.1 0.0 4.5 6.7 0.0 2.4 1 1 0 2 2 2 0 AAA domain PhoH PF02562.11 KEG12447.1 - 0.057 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_10 PF12846.2 KEG12447.1 - 0.071 12.5 0.1 0.27 10.6 0.1 1.9 2 0 0 2 2 2 0 AAA-like domain Mg_chelatase PF01078.16 KEG12447.1 - 0.074 12.1 0.1 0.15 11.2 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF853 PF05872.7 KEG12447.1 - 0.077 11.3 0.3 0.14 10.4 0.2 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DEAD PF00270.24 KEG12447.1 - 0.08 12.4 0.1 2.2 7.7 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase NTPase_1 PF03266.10 KEG12447.1 - 0.088 12.5 0.8 0.64 9.7 0.3 2.3 2 0 0 2 2 2 0 NTPase NACHT PF05729.7 KEG12447.1 - 0.094 12.3 0.1 0.23 11.0 0.1 1.7 1 0 0 1 1 1 0 NACHT domain Herpes_Helicase PF02689.9 KEG12447.1 - 0.32 8.6 0.1 9.1 3.8 0.0 2.1 2 0 0 2 2 2 0 Helicase IstB_IS21 PF01695.12 KEG12447.1 - 0.35 10.2 1.7 4.2 6.7 0.2 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein R3H PF01424.17 KEG12448.1 - 1.4e-09 37.4 0.0 4.1e-09 36.0 0.0 1.9 1 0 0 1 1 1 1 R3H domain DUF975 PF06161.6 KEG12449.1 - 0.044 13.5 0.3 0.056 13.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF975) CAML PF14963.1 KEG12449.1 - 0.22 10.8 1.0 0.31 10.3 0.7 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Nol1_Nop2_Fmu PF01189.12 KEG12450.1 - 0.032 13.6 0.2 0.14 11.5 0.0 1.9 2 0 0 2 2 2 0 NOL1/NOP2/sun family Robl_LC7 PF03259.12 KEG12451.1 - 3e-11 42.7 0.2 3.9e-11 42.3 0.1 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain Toxin_36 PF10550.4 KEG12451.1 - 0.091 13.9 0.2 0.34 12.1 0.1 2.0 1 0 0 1 1 1 0 Conantokin-G mollusc-toxin zf-CCCH PF00642.19 KEG12452.1 - 1.2e-06 28.0 9.2 0.00036 20.1 1.2 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nuc_sug_transp PF04142.10 KEG12453.1 - 1.1e-53 181.8 13.2 1.1e-53 181.8 9.2 1.5 2 0 0 2 2 2 1 Nucleotide-sugar transporter EmrE PF13536.1 KEG12453.1 - 7.8e-10 38.9 6.9 7.8e-10 38.9 4.8 3.4 4 0 0 4 4 4 1 Multidrug resistance efflux transporter TPT PF03151.11 KEG12453.1 - 0.00022 20.9 2.9 0.00022 20.9 2.0 3.4 3 1 0 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 KEG12453.1 - 0.00061 19.8 6.4 0.00061 19.8 4.4 3.2 3 1 1 4 4 4 1 EamA-like transporter family DEAD PF00270.24 KEG12454.1 - 6.1e-14 51.8 0.0 1.8e-13 50.3 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEG12454.1 - 8.7e-08 31.9 0.0 2.1e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEG12454.1 - 3.1e-05 23.8 0.0 0.00011 22.1 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.12 KEG12454.1 - 0.0053 16.1 0.0 0.017 14.5 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.1 KEG12454.1 - 0.0059 16.0 0.0 0.59 9.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KEG12454.1 - 0.0076 16.3 0.0 0.23 11.5 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEG12454.1 - 0.039 13.7 0.0 0.12 12.1 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain SecA_DEAD PF07517.9 KEG12454.1 - 0.08 12.2 0.0 7.1 5.8 0.0 2.2 2 0 0 2 2 2 0 SecA DEAD-like domain PhoH PF02562.11 KEG12454.1 - 0.15 11.3 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein TPR_17 PF13431.1 KEG12455.1 - 1.7e-08 33.9 0.3 0.25 11.6 0.0 5.2 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEG12455.1 - 2.5e-06 28.0 4.2 0.027 15.1 0.1 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 KEG12455.1 - 0.00039 20.0 0.4 5.1 6.8 0.0 3.7 3 0 0 3 3 3 2 TPR repeat TPR_14 PF13428.1 KEG12455.1 - 0.0095 16.4 13.6 2 9.2 0.3 6.5 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEG12455.1 - 0.027 14.3 0.1 21 5.3 0.0 4.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.1 KEG12455.1 - 0.029 13.4 0.0 0.059 12.4 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEG12455.1 - 0.033 14.6 1.5 6.1 7.5 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 KEG12455.1 - 0.24 11.7 4.5 7.6 6.9 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat RRM_1 PF00076.17 KEG12456.1 - 8.7e-13 47.7 0.0 1.7e-10 40.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG12456.1 - 8.3e-12 44.9 0.0 2.6e-10 40.1 0.0 2.6 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG12456.1 - 2.7e-05 23.9 0.0 0.00017 21.3 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATP-synt_D PF01813.12 KEG12456.1 - 0.029 13.9 0.1 0.048 13.2 0.1 1.2 1 0 0 1 1 1 0 ATP synthase subunit D RNase_PH PF01138.16 KEG12457.1 - 2.7e-07 30.9 0.0 4.5e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KEG12457.1 - 0.0068 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 zf-C2HC_2 PF13913.1 KEG12458.1 - 2.2e-23 81.3 13.9 8.5e-10 38.0 0.3 3.4 3 0 0 3 3 3 3 zinc-finger of a C2HC-type zf-ribbon_3 PF13248.1 KEG12458.1 - 6.1e-06 25.2 10.0 6e-05 22.1 0.9 4.0 4 0 0 4 4 4 2 zinc-ribbon domain DZR PF12773.2 KEG12458.1 - 0.00019 21.1 13.5 0.00027 20.6 0.5 4.4 3 1 0 3 3 3 1 Double zinc ribbon zinc_ribbon_2 PF13240.1 KEG12458.1 - 0.0003 20.1 4.1 0.0003 20.1 2.8 3.6 4 0 0 4 4 4 1 zinc-ribbon domain zf-C2H2 PF00096.21 KEG12458.1 - 0.048 14.0 0.6 0.048 14.0 0.4 4.2 5 0 0 5 5 3 0 Zinc finger, C2H2 type Sgf11 PF08209.6 KEG12458.1 - 0.083 12.2 7.2 1 8.7 0.2 2.7 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-H2C2_2 PF13465.1 KEG12458.1 - 0.12 12.6 2.6 12 6.4 0.0 3.6 3 0 0 3 3 3 0 Zinc-finger double domain DUF4187 PF13821.1 KEG12458.1 - 0.18 11.4 2.0 1.8 8.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) HypA PF01155.14 KEG12458.1 - 0.18 11.4 7.6 14 5.4 0.3 3.9 4 0 0 4 4 4 0 Hydrogenase expression/synthesis hypA family DUF164 PF02591.10 KEG12458.1 - 0.47 10.3 3.7 9.2 6.1 0.1 3.3 3 0 0 3 3 3 0 Putative zinc ribbon domain zinc_ribbon_5 PF13719.1 KEG12458.1 - 1.5 8.4 6.1 9.9 5.8 0.0 3.1 3 0 0 3 3 3 0 zinc-ribbon domain RRN7 PF11781.3 KEG12458.1 - 5.3 6.6 6.7 24 4.5 0.1 3.7 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C2H2_jaz PF12171.3 KEG12458.1 - 8.8 6.6 7.9 52 4.1 0.0 4.1 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding DUF2638 PF10937.3 KEG12459.1 - 7e-05 23.8 0.1 0.00012 23.1 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2638) Sedlin_N PF04628.8 KEG12463.1 - 3.9e-06 26.7 0.0 5.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region DUF4460 PF14687.1 KEG12464.1 - 6.4e-09 35.5 0.4 6.4e-09 35.5 0.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4460) DUF4461 PF14688.1 KEG12464.1 - 4.8e-05 22.8 2.8 0.036 13.4 0.0 3.2 2 1 0 2 2 2 2 Domain of unknown function (DUF4461) vATP-synt_E PF01991.13 KEG12464.1 - 8.8 5.5 12.6 0.27 10.4 0.0 2.6 3 0 0 3 3 3 0 ATP synthase (E/31 kDa) subunit LRR_6 PF13516.1 KEG12465.1 - 0.00018 21.2 1.5 8.5 6.7 0.0 4.9 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.2 KEG12465.1 - 0.00079 18.9 0.1 0.46 10.1 0.0 3.4 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEG12465.1 - 0.0077 16.1 1.1 0.55 10.4 0.0 4.2 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_7 PF13504.1 KEG12465.1 - 0.041 14.0 1.9 2.4 8.7 0.1 4.1 4 0 0 4 4 4 0 Leucine rich repeat DUF2096 PF09869.4 KEG12465.1 - 0.062 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) ELMO_CED12 PF04727.8 KEG12467.1 - 2.1e-43 147.8 0.1 3.9e-43 146.9 0.1 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family Methyltransf_26 PF13659.1 KEG12468.1 - 0.67 9.9 4.8 0.18 11.8 0.4 2.1 2 2 1 3 3 3 0 Methyltransferase domain Peptidase_C12 PF01088.16 KEG12470.1 - 9.1e-56 188.4 0.0 1.2e-55 188.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 BBP1_C PF15272.1 KEG12470.1 - 0.061 12.8 0.6 0.098 12.1 0.4 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal RRM_6 PF14259.1 KEG12471.1 - 0.073 13.0 0.0 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ThiF PF00899.16 KEG12473.1 - 2e-32 111.8 0.2 3.4e-32 111.1 0.2 1.3 1 0 0 1 1 1 1 ThiF family KR PF08659.5 KEG12473.1 - 0.01 15.5 0.1 0.039 13.6 0.0 1.9 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 KEG12473.1 - 0.03 14.2 0.2 0.069 13.0 0.1 1.7 2 0 0 2 2 2 0 short chain dehydrogenase DUF3456 PF11938.3 KEG12475.1 - 8.8e-07 29.0 2.8 8.7e-06 25.7 1.9 2.1 1 1 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP LRR_4 PF12799.2 KEG12476.1 - 4.9e-57 188.7 54.4 9.5e-08 31.4 0.0 15.1 12 5 5 17 17 17 14 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG12476.1 - 2.3e-33 113.7 73.3 7.1e-07 28.8 2.9 12.2 10 3 3 13 13 13 9 Leucine rich repeat LRR_9 PF14580.1 KEG12476.1 - 3e-29 101.8 13.2 5.5e-06 26.0 0.0 8.8 4 4 5 9 9 9 7 Leucine-rich repeat LRR_1 PF00560.28 KEG12476.1 - 2.2e-05 23.8 62.8 8.9 6.7 0.1 18.0 17 2 0 17 17 17 4 Leucine Rich Repeat LRR_7 PF13504.1 KEG12476.1 - 0.00092 19.0 52.0 19 6.0 0.2 17.1 19 0 0 19 19 19 0 Leucine rich repeat LRR_5 PF13306.1 KEG12476.1 - 0.024 14.3 0.1 2.5 7.8 0.0 2.5 2 0 0 2 2 2 0 Leucine rich repeats (6 copies) LRR_6 PF13516.1 KEG12476.1 - 0.025 14.6 52.1 13 6.1 0.1 15.5 15 4 4 19 19 19 0 Leucine Rich repeat TctC PF03401.9 KEG12476.1 - 0.087 11.7 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter family receptor Utp14 PF04615.8 KEG12477.1 - 1.2 7.2 8.2 0.56 8.3 0.9 2.0 2 0 0 2 2 2 0 Utp14 protein UPF0147 PF03685.8 KEG12478.1 - 0.047 13.5 1.0 0.24 11.2 0.0 2.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0147) TBPIP PF07106.8 KEG12478.1 - 0.64 9.5 9.9 0.16 11.5 3.5 2.5 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FliD_C PF07195.7 KEG12478.1 - 1.4 8.1 9.6 2.1 7.5 3.0 3.1 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 C-terminus V_ATPase_I PF01496.14 KEG12478.1 - 3.8 5.2 10.1 8.1 4.1 7.0 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DAZAP2 PF11029.3 KEG12478.1 - 5.8 7.3 7.0 0.38 11.2 0.6 2.1 2 0 0 2 2 2 0 DAZ associated protein 2 (DAZAP2) DnaJ PF00226.26 KEG12479.1 - 1e-16 60.4 2.4 1.8e-16 59.5 1.7 1.4 1 0 0 1 1 1 1 DnaJ domain Herpes_capsid PF06112.6 KEG12479.1 - 0.025 14.6 1.8 0.056 13.4 0.2 2.1 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Thioredoxin PF00085.15 KEG12479.1 - 0.12 12.0 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin ENT PF03735.9 KEG12480.1 - 0.00011 21.8 0.1 0.00011 21.8 0.1 1.9 2 0 0 2 2 2 1 ENT domain CHAD PF05235.9 KEG12480.1 - 0.0085 15.6 1.3 0.013 15.1 0.9 1.3 1 0 0 1 1 1 1 CHAD domain T2SK PF03934.8 KEG12480.1 - 0.056 12.6 0.1 0.056 12.6 0.1 1.5 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein K TRM13 PF05206.9 KEG12481.1 - 9.7e-14 51.2 0.0 1.5e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase TRM13 Methyltransf_32 PF13679.1 KEG12481.1 - 1.6e-09 37.6 0.2 1.5e-08 34.3 0.3 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.13 KEG12481.1 - 0.0043 16.2 0.0 0.009 15.2 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KEG12481.1 - 0.011 16.3 0.0 0.45 11.1 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Glyco_tranf_2_3 PF13641.1 KEG12482.1 - 0.0006 19.6 0.4 0.00097 19.0 0.3 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KEG12482.1 - 0.0028 17.3 0.0 0.014 15.1 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 2 GP41 PF00517.12 KEG12482.1 - 0.16 11.5 0.1 0.55 9.7 0.0 1.9 3 0 0 3 3 3 0 Retroviral envelope protein Myosin_head PF00063.16 KEG12483.1 - 5.3e-174 580.0 0.0 1.8e-173 578.2 0.0 1.7 1 1 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.1 KEG12483.1 - 0.042 13.8 0.0 0.042 13.8 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain Hpr_kinase_C PF07475.7 KEG12483.1 - 0.08 12.2 0.0 16 4.7 0.0 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_22 PF13401.1 KEG12483.1 - 0.26 11.4 2.9 0.41 10.7 0.0 2.9 3 1 1 4 4 4 0 AAA domain AAA_17 PF13207.1 KEG12483.1 - 0.53 11.1 3.5 1 10.1 0.0 3.1 2 0 0 2 2 2 0 AAA domain DAO PF01266.19 KEG12484.1 - 3.8e-41 141.1 0.2 2.1e-40 138.7 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KEG12484.1 - 1.2e-05 24.5 0.6 2e-05 23.8 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KEG12484.1 - 0.0017 17.4 3.1 0.02 13.9 2.1 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KEG12484.1 - 0.0024 17.7 0.3 0.0074 16.1 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KEG12484.1 - 0.0044 15.9 3.2 0.0077 15.1 0.8 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KEG12484.1 - 0.019 14.9 1.4 0.044 13.8 0.7 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KEG12484.1 - 0.03 13.1 2.7 0.21 10.4 0.3 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 KEG12484.1 - 0.053 13.1 0.2 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 KEG12484.1 - 0.5 10.8 3.1 0.4 11.1 0.3 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NADH-u_ox-rdase PF10785.4 KEG12485.1 - 2.4e-20 72.5 4.4 6.6e-20 71.1 3.1 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit DUF4137 PF13593.1 KEG12487.1 - 3.7e-58 197.0 16.3 4.4e-58 196.8 11.3 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Peptidase_M8 PF01457.11 KEG12488.1 - 7.5e-88 295.1 0.1 1e-87 294.6 0.1 1.1 1 0 0 1 1 1 1 Leishmanolysin Reprolysin_3 PF13582.1 KEG12488.1 - 0.13 12.8 0.1 0.25 11.8 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like PAPS_reduct PF01507.14 KEG12489.1 - 4.8e-21 75.3 0.1 4.2e-18 65.7 0.0 2.4 2 1 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family Skp1_POZ PF03931.10 KEG12490.1 - 0.00036 20.5 0.0 0.011 15.8 0.0 2.1 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain Skp1_POZ PF03931.10 KEG12491.1 - 0.00021 21.2 0.0 0.0019 18.2 0.0 2.2 1 1 1 2 2 2 1 Skp1 family, tetramerisation domain DUF3439 PF11921.3 KEG12491.1 - 0.0052 16.5 3.2 0.0072 16.0 2.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) SSP160 PF06933.6 KEG12491.1 - 0.11 10.4 1.6 0.11 10.3 1.1 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 zf-HIT PF04438.11 KEG12492.1 - 2.4e-07 30.2 10.3 7.1e-07 28.7 7.1 1.8 1 0 0 1 1 1 1 HIT zinc finger zf-CCCH PF00642.19 KEG12492.1 - 0.0033 17.0 0.9 0.0033 17.0 0.7 2.6 2 1 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KEG12492.1 - 6.5 6.9 13.0 0.68 10.0 0.4 3.6 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type HEAT_2 PF13646.1 KEG12493.1 - 8.2e-07 29.2 1.9 0.0017 18.6 0.1 3.6 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.17 KEG12493.1 - 0.00038 20.3 8.5 7.3 6.9 0.1 5.4 5 0 0 5 5 5 3 HEAT repeat IBV_3A PF03617.8 KEG12494.1 - 0.25 11.1 3.0 0.36 10.6 0.2 2.5 2 0 0 2 2 2 0 IBV 3A protein DUF3418 PF11898.3 KEG12495.1 - 0.12 10.7 0.0 0.14 10.4 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) OsmC PF02566.14 KEG12497.1 - 0.00025 21.1 0.0 0.00037 20.6 0.0 1.3 1 1 0 1 1 1 1 OsmC-like protein ATP-synt_F PF01990.12 KEG12499.1 - 5.8e-32 109.9 0.1 7e-32 109.6 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit PGI PF00342.14 KEG12500.1 - 9.8e-230 763.0 0.3 1.1e-229 762.7 0.2 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF3268 PF11672.3 KEG12502.1 - 0.033 14.2 0.0 0.079 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3268) Mu-like_Pro PF10123.4 KEG12502.1 - 0.43 9.9 3.0 2.9 7.2 0.1 2.1 2 0 0 2 2 2 0 Mu-like prophage I protein GAS PF13851.1 KEG12502.1 - 3.5 6.7 9.4 0.072 12.2 2.0 1.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TPR_11 PF13414.1 KEG12504.1 - 5.5e-12 45.1 13.0 0.00093 18.7 0.0 6.6 6 0 0 6 6 6 3 TPR repeat TPR_2 PF07719.12 KEG12504.1 - 3.6e-08 32.7 17.5 0.067 13.1 0.0 8.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 KEG12504.1 - 8.5e-06 26.0 5.2 0.95 9.8 0.1 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 KEG12504.1 - 0.00021 20.8 1.2 0.062 13.1 0.0 5.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEG12504.1 - 0.0023 17.4 6.9 9.7 5.9 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat BSP_II PF05432.6 KEG12504.1 - 0.0051 16.1 11.4 0.0051 16.1 7.9 3.0 3 1 0 3 3 2 1 Bone sialoprotein II (BSP-II) TPR_17 PF13431.1 KEG12504.1 - 0.012 15.7 0.1 25 5.4 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 KEG12504.1 - 0.025 15.2 26.7 0.096 13.3 0.0 7.0 6 1 0 6 6 6 0 Tetratricopeptide repeat Mso1_Sec1_bdg PF14475.1 KEG12504.1 - 0.054 12.8 0.0 11 5.5 0.0 2.6 2 0 0 2 2 2 0 Sec1-binding region of Mso1 TPR_14 PF13428.1 KEG12504.1 - 0.089 13.4 30.8 2.4 9.0 0.2 8.9 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_7 PF13176.1 KEG12504.1 - 1.9 8.4 12.3 5.4 7.0 0.1 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat FUSC_2 PF13515.1 KEG12505.1 - 1.8e-13 50.4 29.5 5e-13 49.0 7.9 2.7 3 0 0 3 3 3 2 Fusaric acid resistance protein-like ALMT PF11744.3 KEG12505.1 - 0.57 8.7 11.1 0.026 13.1 2.0 2.3 2 0 0 2 2 2 0 Aluminium activated malate transporter Packaging_FI PF14000.1 KEG12505.1 - 1.1 9.4 10.2 0.061 13.5 1.5 2.5 2 0 0 2 2 2 0 DNA packaging protein FI Sulfatase PF00884.18 KEG12506.1 - 2e-06 27.2 0.0 4.1e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KEG12506.1 - 0.00045 19.6 0.1 0.02 14.1 0.1 2.7 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase TPR_11 PF13414.1 KEG12507.1 - 8.2e-17 60.6 11.5 1.6e-07 30.8 0.1 6.4 5 1 2 7 7 7 4 TPR repeat TPR_8 PF13181.1 KEG12507.1 - 2.6e-14 51.8 1.8 0.00021 20.8 0.0 6.6 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEG12507.1 - 3.2e-13 48.4 24.6 0.0034 17.1 0.1 8.8 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.23 KEG12507.1 - 1.1e-11 43.7 11.0 0.00037 19.9 0.0 7.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 KEG12507.1 - 1.6e-09 37.1 3.7 0.08 13.1 0.0 5.7 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 KEG12507.1 - 3.2e-09 36.5 24.1 0.059 13.3 0.7 7.9 4 1 6 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.1 KEG12507.1 - 8.2e-09 35.3 22.5 0.00047 20.5 0.6 8.0 7 2 1 8 8 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEG12507.1 - 3.8e-08 33.5 6.0 0.0054 17.0 0.0 5.6 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEG12507.1 - 2.5e-07 31.1 29.6 0.00015 22.3 0.6 7.7 5 2 3 8 8 7 2 Tetratricopeptide repeat Apc3 PF12895.2 KEG12507.1 - 3.8e-05 23.7 9.5 0.28 11.3 0.0 5.3 3 1 5 8 8 8 3 Anaphase-promoting complex, cyclosome, subunit 3 APC8 PF04049.8 KEG12507.1 - 0.00018 21.2 0.0 0.0005 19.8 0.0 1.7 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_15 PF13429.1 KEG12507.1 - 0.00022 20.4 2.0 0.00071 18.7 1.4 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEG12507.1 - 0.063 13.1 14.8 0.52 10.2 0.3 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat Gly-zipper_OmpA PF13436.1 KEG12507.1 - 0.19 11.3 11.1 0.03 13.9 3.5 2.8 3 0 0 3 3 3 0 Glycine-zipper containing OmpA-like membrane domain TPR_9 PF13371.1 KEG12507.1 - 0.43 10.4 7.9 0.33 10.8 0.4 3.9 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEG12507.1 - 1.4 9.5 15.2 6.6 7.4 0.1 7.1 9 1 0 9 9 6 0 Tetratricopeptide repeat GAS PF13851.1 KEG12508.1 - 0.064 12.4 15.3 0.44 9.7 4.0 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding EURL PF06937.6 KEG12508.1 - 0.11 11.8 7.9 0.14 11.5 5.5 1.2 1 0 0 1 1 1 0 EURL protein TPR_MLP1_2 PF07926.7 KEG12508.1 - 0.14 11.9 21.2 0.014 15.1 10.9 1.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3450 PF11932.3 KEG12508.1 - 0.72 9.0 21.6 1.4 8.1 5.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) CDC37_N PF03234.9 KEG12508.1 - 2.2 8.6 9.9 5.8 7.1 7.0 1.6 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding Bap31 PF05529.7 KEG12508.1 - 4.8 6.5 6.4 10 5.4 0.0 2.3 2 1 0 2 2 2 0 B-cell receptor-associated protein 31-like APG6 PF04111.7 KEG12508.1 - 4.9 6.0 20.5 79 2.1 14.4 2.0 1 1 0 1 1 1 0 Autophagy protein Apg6 GSHPx PF00255.14 KEG12509.1 - 8.8e-39 131.2 0.1 1.1e-38 130.8 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase Redoxin PF08534.5 KEG12509.1 - 4.1e-05 23.1 0.0 0.00011 21.7 0.0 1.9 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KEG12509.1 - 4.4e-05 23.1 0.1 9.3e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family GSHPx PF00255.14 KEG12510.1 - 0.001 18.4 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione peroxidase GSHPx PF00255.14 KEG12511.1 - 5.7e-40 135.0 0.3 6.9e-40 134.7 0.2 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 KEG12511.1 - 2.1e-06 27.4 0.1 4.9e-06 26.2 0.1 1.7 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KEG12511.1 - 0.00021 20.8 0.0 0.00036 20.0 0.0 1.6 1 1 0 1 1 1 1 Redoxin Myosin_TH1 PF06017.8 KEG12512.1 - 0.069 12.4 0.0 0.36 10.1 0.0 2.1 2 0 0 2 2 2 0 Myosin tail AsnA PF03590.10 KEG12513.1 - 1.7e-102 342.0 0.1 2.4e-101 338.2 0.1 2.0 1 1 0 1 1 1 1 Aspartate-ammonia ligase tRNA-synt_2 PF00152.15 KEG12513.1 - 8.8e-05 21.4 0.0 0.0092 14.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) WW PF00397.21 KEG12515.1 - 5.9e-08 32.4 2.3 1.3e-07 31.3 1.6 1.7 1 0 0 1 1 1 1 WW domain NDUF_B5 PF09781.4 KEG12515.1 - 0.039 13.2 1.9 0.12 11.6 1.3 1.8 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit HALZ PF02183.13 KEG12515.1 - 0.25 11.0 4.8 3.6 7.3 0.1 3.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper Nuc-transf PF10127.4 KEG12517.1 - 0.0023 17.3 0.1 0.0036 16.6 0.0 1.2 1 0 0 1 1 1 1 Predicted nucleotidyltransferase IF3_N PF05198.11 KEG12517.1 - 0.0051 16.7 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain Transpep_BrtH PF14399.1 KEG12517.1 - 0.054 12.7 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 NlpC/p60-like transpeptidase Exo_endo_phos PF03372.18 KEG12518.1 - 6.5e-14 52.4 0.0 1e-13 51.8 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family XRN_N PF03159.13 KEG12518.1 - 0.00048 19.5 0.0 0.0026 17.2 0.0 2.0 1 1 1 2 2 2 1 XRN 5'-3' exonuclease N-terminus FYRC PF05965.9 KEG12519.1 - 2e-06 27.5 0.0 4.1e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.9 KEG12519.1 - 0.084 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 F/Y-rich N-terminus Mito_fiss_reg PF05308.6 KEG12519.1 - 0.34 10.2 19.3 0.17 11.1 2.9 3.0 3 1 0 3 3 3 0 Mitochondrial fission regulator Ribosomal_S9 PF00380.14 KEG12520.1 - 3.7e-29 101.4 1.9 4.4e-29 101.1 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S9/S16 2-Hacid_dh_C PF02826.14 KEG12520.1 - 0.078 12.1 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Kinesin PF00225.18 KEG12521.1 - 6.4e-32 110.5 0.0 7.1e-32 110.4 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain PIF1 PF05970.9 KEG12521.1 - 0.059 12.3 0.0 0.086 11.7 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_23 PF13476.1 KEG12521.1 - 0.1 12.8 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain Kinesin PF00225.18 KEG12522.1 - 1.2e-93 313.5 0.0 1.4e-93 313.2 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain AAA_23 PF13476.1 KEG12522.1 - 0.16 12.2 0.2 0.24 11.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain Helicase_C PF00271.26 KEG12524.1 - 2.5e-06 27.2 0.0 6.5e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEG12524.1 - 2.5e-05 23.8 0.0 5.2e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase DAP3 PF10236.4 KEG12524.1 - 0.023 13.6 0.0 0.048 12.5 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DUF2388 PF09498.5 KEG12524.1 - 0.093 12.3 0.1 0.45 10.1 0.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2388) T2SE PF00437.15 KEG12524.1 - 0.11 11.3 0.0 0.2 10.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein UQ_con PF00179.21 KEG12525.1 - 7.1e-19 67.6 0.0 8.9e-19 67.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KEG12525.1 - 0.0002 21.1 0.1 0.00026 20.8 0.1 1.3 1 1 0 1 1 1 1 RWD domain HMGL-like PF00682.14 KEG12526.1 - 4.2e-27 95.3 0.0 5.9e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 HMGL-like EF-hand_1 PF00036.27 KEG12526.1 - 5e-05 22.3 0.0 0.00046 19.2 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 KEG12526.1 - 0.0001 22.3 0.0 0.00022 21.2 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KEG12526.1 - 0.00077 19.1 0.0 0.0067 16.2 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 KEG12526.1 - 0.12 11.8 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 EF hand Zeta_toxin PF06414.7 KEG12527.1 - 3.8e-13 48.9 0.0 2e-12 46.6 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 KEG12527.1 - 7.3e-05 22.6 0.1 0.00016 21.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KEG12527.1 - 0.0023 17.1 0.0 0.0044 16.2 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 KEG12527.1 - 0.017 15.9 0.0 0.04 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KEG12527.1 - 0.026 14.8 0.0 0.053 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Thioredoxin PF00085.15 KEG12527.1 - 0.047 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin Peptidase_C15 PF01470.12 KEG12528.1 - 4.6e-08 33.1 0.0 0.001 18.9 0.0 2.3 2 0 0 2 2 2 2 Pyroglutamyl peptidase S-AdoMet_synt_N PF00438.15 KEG12530.1 - 0.11 12.7 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 S-adenosylmethionine synthetase, N-terminal domain ArfGap PF01412.13 KEG12530.1 - 0.15 11.8 0.2 0.23 11.2 0.1 1.2 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf RCC1 PF00415.13 KEG12531.1 - 3.5e-31 107.1 0.8 3.9e-11 42.9 0.0 4.5 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KEG12531.1 - 5.6e-18 64.0 9.4 3.9e-09 35.8 0.6 4.5 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat TPR_12 PF13424.1 KEG12532.1 - 1.5e-08 34.4 1.8 7.4e-06 25.8 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 KEG12532.1 - 6.3e-07 29.1 1.7 0.0099 15.7 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat IQ PF00612.22 KEG12532.1 - 9.9e-07 27.8 48.0 0.026 14.1 0.6 8.1 8 0 0 8 8 8 6 IQ calmodulin-binding motif DUF4484 PF14831.1 KEG12532.1 - 0.18 11.9 4.6 0.46 10.5 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) DBP10CT PF08147.7 KEG12533.1 - 3.3e-09 36.4 2.8 7e-09 35.3 2.0 1.6 1 0 0 1 1 1 1 DBP10CT (NUC160) domain dsrm PF00035.20 KEG12534.1 - 6.7e-08 33.0 0.2 0.043 14.3 0.0 5.0 5 0 0 5 5 5 2 Double-stranded RNA binding motif SYS1 PF09801.4 KEG12535.1 - 1e-34 119.6 5.6 1.3e-34 119.2 3.9 1.1 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network PIG-H PF10181.4 KEG12535.1 - 0.078 12.6 0.7 2.6 7.7 0.2 2.4 2 0 0 2 2 2 0 GPI-GlcNAc transferase complex, PIG-H component EMP70 PF02990.11 KEG12536.1 - 1.1e-148 496.0 6.0 1.3e-148 495.7 4.2 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 Ycf4 PF02392.11 KEG12536.1 - 1.1 8.5 11.2 0.17 11.1 4.6 1.9 1 1 1 2 2 2 0 Ycf4 DUF2152 PF10222.4 KEG12536.1 - 3.9 5.5 4.3 6.9 4.7 3.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2152) UBA PF00627.26 KEG12540.1 - 4.6e-09 35.8 0.2 1.5e-08 34.1 0.0 2.1 2 0 0 2 2 2 1 UBA/TS-N domain XPC-binding PF09280.6 KEG12540.1 - 9.1e-07 28.2 5.0 9.1e-07 28.2 3.4 2.2 1 1 1 2 2 2 1 XPC-binding domain CLTH PF10607.4 KEG12540.1 - 0.16 11.6 2.7 0.27 10.9 1.9 1.6 1 1 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain WD40 PF00400.27 KEG12541.1 - 0.0029 17.4 0.1 0.047 13.5 0.0 2.6 2 0 0 2 2 2 1 WD domain, G-beta repeat RabGAP-TBC PF00566.13 KEG12542.1 - 2.6e-44 151.2 0.0 4.3e-44 150.5 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Nodulin-like PF06813.8 KEG12546.1 - 1.3e-09 37.6 12.8 1.6e-09 37.4 8.9 1.0 1 0 0 1 1 1 1 Nodulin-like DUF2427 PF10348.4 KEG12546.1 - 0.011 15.3 0.7 0.024 14.2 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) DUF485 PF04341.7 KEG12546.1 - 8.8 6.1 10.3 0.27 10.9 0.7 2.5 1 1 2 3 3 3 0 Protein of unknown function, DUF485 Peptidase_C1 PF00112.18 KEG12550.1 - 2.2e-59 200.9 3.8 2.9e-59 200.6 2.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 KEG12550.1 - 4.2e-11 42.9 0.1 6.5e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 KEG12550.1 - 0.034 12.6 0.5 0.053 12.0 0.1 1.4 2 0 0 2 2 2 0 Peptidase C1-like family Acetyltransf_9 PF13527.1 KEG12551.1 - 0.083 12.7 0.1 0.26 11.1 0.1 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2443 PF10398.4 KEG12551.1 - 0.3 10.9 2.8 0.97 9.2 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2443) Reo_sigmaC PF04582.7 KEG12551.1 - 0.49 9.5 12.9 1.5 7.9 0.6 3.9 4 0 0 4 4 4 0 Reovirus sigma C capsid protein Mnd1 PF03962.10 KEG12551.1 - 5.1 6.7 36.2 0.33 10.5 0.5 4.6 4 0 0 4 4 4 0 Mnd1 family DFP PF04127.10 KEG12552.1 - 0.066 12.8 0.2 0.093 12.3 0.1 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein DUF1517 PF07466.6 KEG12555.1 - 0.22 10.4 0.4 0.27 10.1 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Pkinase PF00069.20 KEG12558.1 - 4.4e-25 88.3 0.0 1e-24 87.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG12558.1 - 1.8e-12 46.9 0.0 3.3e-11 42.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 KEG12558.1 - 0.0022 16.8 0.1 0.0028 16.5 0.1 1.1 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.1 KEG12558.1 - 0.079 11.9 0.0 0.099 11.5 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Got1 PF04178.7 KEG12559.1 - 1.7e-26 92.6 11.1 2.4e-26 92.1 7.7 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF4227 PF14004.1 KEG12559.1 - 0.11 12.3 1.9 4.1 7.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4227) DUF1625 PF07787.7 KEG12559.1 - 0.44 9.7 2.5 1.9 7.6 1.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1625) Flavi_NS4B PF01349.12 KEG12559.1 - 3.7 6.4 6.2 0.54 9.1 0.2 1.9 1 1 1 2 2 2 0 Flavivirus non-structural protein NS4B ABC_membrane PF00664.18 KEG12560.1 - 5.4e-81 272.0 31.3 1.2e-45 156.1 7.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KEG12560.1 - 2.5e-69 231.8 0.0 1.6e-33 115.9 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KEG12560.1 - 3.2e-11 43.7 0.3 0.03 14.2 0.0 4.7 4 1 1 5 5 4 3 AAA domain SMC_N PF02463.14 KEG12560.1 - 3.7e-11 42.6 0.0 0.00028 20.1 0.0 3.8 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KEG12560.1 - 2.3e-07 31.6 0.0 0.0041 17.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KEG12560.1 - 1.8e-06 28.1 5.6 0.072 13.2 0.6 3.9 2 2 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KEG12560.1 - 3.7e-06 26.1 0.0 0.014 14.5 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_29 PF13555.1 KEG12560.1 - 1.1e-05 24.8 0.3 0.049 13.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.1 KEG12560.1 - 3.6e-05 23.5 3.3 0.26 11.2 0.2 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 KEG12560.1 - 7.1e-05 22.8 2.9 0.087 12.8 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 KEG12560.1 - 7.5e-05 21.9 0.1 0.2 10.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_14 PF13173.1 KEG12560.1 - 0.0001 22.2 0.0 0.065 13.1 0.0 3.6 3 1 0 3 3 2 1 AAA domain AAA_18 PF13238.1 KEG12560.1 - 0.00012 22.3 0.0 0.5 10.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 KEG12560.1 - 0.00012 20.8 0.1 0.11 11.0 0.0 2.3 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA PF00004.24 KEG12560.1 - 0.00018 21.7 1.3 1.4 9.1 0.4 3.9 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KEG12560.1 - 0.00031 20.1 0.1 6.1 6.1 0.1 4.1 3 1 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.20 KEG12560.1 - 0.00043 19.8 0.0 1 8.8 0.0 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain Viral_helicase1 PF01443.13 KEG12560.1 - 0.00071 19.1 0.1 1.1 8.6 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.9 KEG12560.1 - 0.0012 18.5 0.2 0.73 9.5 0.0 3.6 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) G-alpha PF00503.15 KEG12560.1 - 0.0013 17.5 0.0 0.16 10.6 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit ArgK PF03308.11 KEG12560.1 - 0.0021 16.8 0.1 0.57 8.8 0.0 2.4 2 0 0 2 2 2 1 ArgK protein AAA_23 PF13476.1 KEG12560.1 - 0.0023 18.3 0.6 0.7 10.1 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 KEG12560.1 - 0.0044 16.6 0.2 5 6.6 0.0 3.5 4 0 0 4 4 4 0 AAA domain T2SE PF00437.15 KEG12560.1 - 0.011 14.6 0.0 0.93 8.3 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF87 PF01935.12 KEG12560.1 - 0.015 15.0 0.7 2.4 7.9 0.1 2.7 3 0 0 3 3 2 0 Domain of unknown function DUF87 Rad17 PF03215.10 KEG12560.1 - 0.018 13.7 0.0 0.21 10.2 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein APS_kinase PF01583.15 KEG12560.1 - 0.02 14.5 0.1 0.37 10.4 0.0 2.8 3 0 0 3 3 3 0 Adenylylsulphate kinase RNA_helicase PF00910.17 KEG12560.1 - 0.04 14.1 0.0 5.9 7.1 0.0 2.8 2 0 0 2 2 2 0 RNA helicase SRP54 PF00448.17 KEG12560.1 - 0.079 12.3 0.1 5.5 6.3 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.18 KEG12560.1 - 0.094 12.6 0.0 28 4.7 0.0 3.1 3 0 0 3 3 2 0 50S ribosome-binding GTPase DUF815 PF05673.8 KEG12560.1 - 0.13 11.1 0.0 2.8 6.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MobB PF03205.9 KEG12560.1 - 0.14 11.8 0.2 3.7 7.2 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.1 KEG12560.1 - 0.15 11.0 0.0 5.9 5.8 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 KEG12560.1 - 0.19 11.6 1.7 8.5 6.3 0.1 2.7 3 0 0 3 3 2 0 AAA domain Cauli_DNA-bind PF03310.8 KEG12561.1 - 0.00018 21.3 2.2 0.00018 21.3 1.5 3.5 2 1 2 4 4 4 1 Caulimovirus DNA-binding protein TPD52 PF04201.10 KEG12561.1 - 0.00074 19.2 6.4 0.00074 19.2 4.5 6.1 4 2 2 6 6 6 1 Tumour protein D52 family DUF4578 PF15147.1 KEG12561.1 - 0.56 10.5 0.0 0.56 10.5 0.0 4.2 4 2 1 5 5 5 0 Domain of unknown function (DUF4578) HECT PF00632.20 KEG12562.1 - 2.8e-10 39.8 0.1 8.3e-05 21.8 0.0 3.2 3 0 0 3 3 3 3 HECT-domain (ubiquitin-transferase) Rio2_N PF09202.6 KEG12563.1 - 0.079 13.0 0.2 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Rio2, N-terminal CECR6_TMEM121 PF14997.1 KEG12565.1 - 2e-07 30.8 6.5 4.3e-07 29.7 0.3 3.0 3 0 0 3 3 3 2 CECR6/TMEM121 family RRF PF01765.14 KEG12566.1 - 0.0092 15.4 0.2 0.022 14.2 0.0 1.7 2 0 0 2 2 2 1 Ribosome recycling factor PPO1_DWL PF12142.3 KEG12566.1 - 0.026 14.0 0.3 0.83 9.2 0.0 2.4 2 0 0 2 2 2 0 Polyphenol oxidase middle domain ubiquitin PF00240.18 KEG12566.1 - 0.027 13.8 0.0 0.08 12.3 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin family Flg_hook PF02120.11 KEG12566.1 - 0.1 12.3 0.1 0.1 12.3 0.0 2.5 4 1 0 4 4 4 0 Flagellar hook-length control protein FliK Dor1 PF04124.7 KEG12566.1 - 0.2 10.1 2.1 0.33 9.3 1.5 1.2 1 0 0 1 1 1 0 Dor1-like family CENP-F_leu_zip PF10473.4 KEG12566.1 - 1.2 9.0 8.8 0.12 12.2 1.3 2.6 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HAUS6_N PF14661.1 KEG12566.1 - 2.8 7.2 6.0 0.3 10.4 0.9 1.7 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Lebercilin PF15619.1 KEG12566.1 - 4.2 6.7 7.6 0.37 10.1 1.7 1.9 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease zf-CSL PF05207.8 KEG12567.1 - 8.7e-16 57.1 0.2 1.2e-15 56.7 0.2 1.2 1 0 0 1 1 1 1 CSL zinc finger Synaptobrevin PF00957.16 KEG12568.1 - 2.8e-21 74.8 2.7 4.2e-21 74.3 1.9 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 KEG12568.1 - 1.2e-07 31.1 0.0 2e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain FAD_binding_3 PF01494.14 KEG12569.1 - 6.5e-10 38.5 0.2 4.5e-05 22.6 0.0 2.9 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 KEG12569.1 - 4.1e-07 29.2 0.1 0.00019 20.4 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEG12569.1 - 8.6e-07 28.8 0.1 2.8e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KEG12569.1 - 3.5e-05 22.8 0.1 0.00014 20.8 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 KEG12569.1 - 3.9e-05 23.9 0.0 9.9e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEG12569.1 - 0.011 14.6 0.0 0.042 12.7 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KEG12569.1 - 0.017 14.9 0.0 0.043 13.6 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEG12569.1 - 0.02 14.0 0.0 0.036 13.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 KEG12569.1 - 0.029 14.4 0.0 0.7 9.9 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KEG12569.1 - 0.061 12.2 0.0 0.52 9.1 0.0 2.3 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KEG12569.1 - 0.087 12.6 0.1 1.8 8.2 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding HTH_Tnp_Mu_2 PF09039.6 KEG12571.1 - 0.017 14.8 0.2 0.63 9.8 0.0 2.6 2 0 0 2 2 2 0 Mu DNA binding, I gamma subdomain bZIP_Maf PF03131.12 KEG12571.1 - 5.7 7.3 10.5 2.5 8.4 1.0 3.6 3 1 1 4 4 4 0 bZIP Maf transcription factor DUF2569 PF10754.4 KEG12572.1 - 0.046 13.9 0.2 0.046 13.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) HAMP PF00672.20 KEG12572.1 - 0.11 12.7 0.7 0.32 11.2 0.0 2.0 2 0 0 2 2 2 0 HAMP domain PCI PF01399.22 KEG12575.1 - 9.9e-06 25.8 0.0 1.5e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 PCI domain bZIP_1 PF00170.16 KEG12576.1 - 0.042 13.8 0.5 0.042 13.8 0.3 6.2 6 1 0 6 6 6 0 bZIP transcription factor CENP-F_leu_zip PF10473.4 KEG12576.1 - 0.095 12.5 48.3 0.13 12.0 6.4 6.2 6 1 0 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 KEG12576.1 - 2.5 7.1 17.4 2.6 7.1 0.7 3.6 3 2 1 4 4 4 0 Reovirus sigma C capsid protein V_ATPase_I PF01496.14 KEG12576.1 - 7.2 4.3 24.6 32 2.1 0.0 3.8 2 1 2 4 4 4 0 V-type ATPase 116kDa subunit family ATG16 PF08614.6 KEG12576.1 - 7.5 6.3 47.9 6.5 6.5 5.6 5.6 3 2 1 4 4 4 0 Autophagy protein 16 (ATG16) Fcf2 PF08698.6 KEG12577.1 - 2e-19 69.3 0.3 2e-19 69.3 0.2 2.6 1 1 2 3 3 3 2 Fcf2 pre-rRNA processing NEP PF10167.4 KEG12578.1 - 1.1e-05 25.0 0.0 1.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein RapA_C PF12137.3 KEG12578.1 - 0.043 12.6 0.0 0.053 12.3 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal DUF1308 PF07000.6 KEG12580.1 - 9e-79 264.7 0.1 1.2e-78 264.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) zf-RING_2 PF13639.1 KEG12581.1 - 6.9e-12 45.0 8.7 6.9e-12 45.0 6.0 2.1 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 KEG12581.1 - 2.1e-05 24.5 3.5 2.1e-05 24.5 2.4 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KEG12581.1 - 7.2e-05 22.4 6.4 7.2e-05 22.4 4.4 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KEG12581.1 - 7.3e-05 22.7 8.0 7.3e-05 22.7 5.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEG12581.1 - 0.00016 21.2 6.2 0.00016 21.2 4.3 2.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KEG12581.1 - 0.00035 20.3 3.7 0.00079 19.2 2.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 KEG12581.1 - 0.0012 18.4 8.5 0.0046 16.5 5.9 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 KEG12581.1 - 0.0042 16.7 9.4 0.048 13.3 5.8 2.6 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H_2 PF13832.1 KEG12581.1 - 0.0046 16.9 0.8 0.012 15.6 0.5 1.6 1 0 0 1 1 1 1 PHD-zinc-finger like domain SPRY PF00622.23 KEG12582.1 - 3.1e-09 36.9 0.0 6.1e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 SPRY domain B9-C2 PF07162.6 KEG12583.1 - 2.8e-48 163.8 0.0 3.4e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein DUF2217 PF10265.4 KEG12584.1 - 0.053 12.2 0.2 0.11 11.2 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) ATP_bind_4 PF01902.12 KEG12586.1 - 6.1e-29 100.9 0.0 1.6e-27 96.2 0.0 2.4 1 1 0 1 1 1 1 ATP-binding region YTH PF04146.10 KEG12587.1 - 6.3e-05 22.5 0.0 0.0002 20.9 0.0 1.7 1 1 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.17 KEG12587.1 - 0.001 18.6 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG12587.1 - 0.0016 18.3 0.0 0.0028 17.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Phage_GP20 PF06810.6 KEG12588.1 - 1.8 7.9 9.9 0.18 11.2 2.4 2.4 2 0 0 2 2 2 0 Phage minor structural protein GP20 DUF4200 PF13863.1 KEG12588.1 - 6.2 6.7 18.2 0.23 11.4 3.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) MADF_DNA_bdg PF10545.4 KEG12589.1 - 0.12 12.6 4.0 9.3 6.5 0.1 3.8 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Dynein_light PF01221.13 KEG12590.1 - 1.9e-37 127.0 0.8 2.1e-37 126.9 0.5 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 DUF950 PF06106.6 KEG12590.1 - 0.11 12.6 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Staphylococcus protein of unknown function (DUF950) Ectatomin PF06457.6 KEG12590.1 - 0.11 12.1 0.3 0.19 11.4 0.2 1.5 1 0 0 1 1 1 0 Ectatomin U-box PF04564.10 KEG12591.1 - 0.031 14.2 0.0 0.077 12.9 0.0 1.7 1 0 0 1 1 1 0 U-box domain FliJ PF02050.11 KEG12591.1 - 0.049 13.6 0.6 0.049 13.6 0.4 2.4 3 0 0 3 3 3 0 Flagellar FliJ protein TCR PF03638.10 KEG12591.1 - 3.4 7.5 7.0 0.39 10.6 1.9 1.6 2 0 0 2 2 2 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain SOG2 PF10428.4 KEG12592.1 - 1.9 7.0 8.8 2.1 6.9 6.1 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein UPF0016 PF01169.14 KEG12594.1 - 4.1e-43 145.3 21.6 3.1e-23 81.6 4.4 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TerC PF03741.11 KEG12594.1 - 0.0028 17.1 2.7 0.094 12.1 0.2 2.4 2 0 0 2 2 2 2 Integral membrane protein TerC family DUF3995 PF13160.1 KEG12594.1 - 0.027 14.5 3.3 1.7 8.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) ABC_transp_aux PF09822.4 KEG12595.1 - 3e-06 26.8 0.0 5e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 ABC-type uncharacterized transport system DUF1355 PF07090.6 KEG12595.1 - 0.00075 18.9 0.0 0.0018 17.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1355) ThuA PF06283.6 KEG12595.1 - 0.0066 16.1 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Trehalose utilisation DUF4159 PF13709.1 KEG12595.1 - 0.0076 15.3 0.0 0.02 13.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4159) WD40 PF00400.27 KEG12596.1 - 9.2e-18 63.3 14.8 1.3e-06 28.0 0.1 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat EF-hand_7 PF13499.1 KEG12597.1 - 0.00029 20.9 0.2 0.019 15.0 0.0 3.5 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_8 PF13833.1 KEG12597.1 - 0.0013 18.3 0.8 2.5 7.7 0.0 4.1 4 0 0 4 4 4 1 EF-hand domain pair DUF1143 PF06608.6 KEG12597.1 - 0.0019 18.2 0.2 0.005 16.8 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1143) EF-hand_1 PF00036.27 KEG12597.1 - 0.0025 17.0 0.6 26 4.4 0.0 4.4 4 0 0 4 4 4 0 EF hand EF-hand_6 PF13405.1 KEG12597.1 - 0.0064 16.2 0.1 25 5.1 0.0 4.0 4 0 0 4 4 4 1 EF-hand domain Sigma70_r1_1 PF03979.9 KEG12597.1 - 0.068 13.1 0.6 0.28 11.1 0.1 2.1 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 Radical_SAM PF04055.16 KEG12598.1 - 2.2e-10 40.9 0.1 3.2e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Pkinase PF00069.20 KEG12599.1 - 1.5e-32 112.8 0.1 7.6e-18 64.5 0.0 4.4 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 KEG12599.1 - 0.00069 18.7 3.5 0.54 9.2 0.2 4.4 4 0 0 4 4 4 2 Protein tyrosine kinase DUF3709 PF12493.3 KEG12599.1 - 0.0079 15.8 0.3 0.017 14.7 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3709) RIO1 PF01163.17 KEG12599.1 - 0.032 13.5 0.1 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Pox_ser-thr_kin PF05445.6 KEG12599.1 - 0.4 9.4 0.0 0.59 8.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase WD40 PF00400.27 KEG12603.1 - 2e-06 27.4 0.1 1.4e-05 24.7 0.0 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat PrgI PF12666.2 KEG12604.1 - 0.041 14.0 0.7 0.21 11.7 0.0 2.0 2 0 0 2 2 2 0 PrgI family protein DUF2189 PF09955.4 KEG12604.1 - 0.044 13.7 0.2 0.044 13.7 0.1 2.0 1 1 2 3 3 3 0 Predicted integral membrane protein (DUF2189) Peptidase_M8 PF01457.11 KEG12605.1 - 2.7e-106 356.0 8.1 1.3e-59 201.9 4.6 2.1 2 0 0 2 2 2 2 Leishmanolysin Reprolysin_5 PF13688.1 KEG12605.1 - 0.00017 21.5 0.0 0.00038 20.4 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M57 PF12388.3 KEG12605.1 - 0.0058 15.9 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Reprolysin_3 PF13582.1 KEG12605.1 - 0.017 15.6 0.1 0.037 14.5 0.1 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Sipho_Gp157 PF05565.6 KEG12605.1 - 0.075 12.6 0.1 0.95 9.0 0.0 2.1 2 0 0 2 2 2 0 Siphovirus Gp157 PP2C PF00481.16 KEG12610.1 - 9.5e-32 110.3 0.0 1.3e-30 106.6 0.0 2.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KEG12610.1 - 0.031 13.9 0.1 0.15 11.7 0.0 2.2 3 0 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) PTH2 PF01981.11 KEG12611.1 - 5e-49 164.8 0.1 6.5e-49 164.4 0.1 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Oxidored_FMN PF00724.15 KEG12613.1 - 9.6e-46 156.3 0.0 1.2e-45 155.9 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.9 KEG12613.1 - 3.8e-11 43.2 0.0 1.3e-10 41.5 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEG12613.1 - 3.4e-09 36.5 0.0 1.6e-08 34.4 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEG12613.1 - 9.9e-09 34.5 0.7 6.5e-07 28.5 0.6 2.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEG12613.1 - 5.3e-08 33.1 0.2 0.0023 18.0 0.1 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEG12613.1 - 4.7e-07 30.1 0.3 0.00087 19.6 0.2 3.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KEG12613.1 - 8.9e-07 28.3 0.1 1.4e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KEG12613.1 - 2.7e-06 26.1 0.3 1.5e-05 23.6 0.1 2.1 1 1 1 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 KEG12613.1 - 6.6e-06 25.2 1.2 1.7e-05 23.8 0.9 1.7 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KEG12613.1 - 0.00037 19.6 0.1 0.00069 18.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.19 KEG12613.1 - 0.00057 19.0 0.1 0.00094 18.3 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FMO-like PF00743.14 KEG12613.1 - 0.0023 16.2 0.1 0.6 8.2 0.1 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like GIDA PF01134.17 KEG12613.1 - 0.0027 16.6 0.9 0.0041 16.0 0.6 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A ApbA PF02558.11 KEG12613.1 - 0.0033 16.8 0.4 0.014 14.8 0.1 2.1 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 KEG12613.1 - 0.014 15.0 0.5 0.087 12.4 0.2 2.3 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KEG12613.1 - 0.029 14.3 1.2 0.16 11.9 0.2 2.6 3 0 0 3 3 3 0 NADH(P)-binding NAD_Gly3P_dh_N PF01210.18 KEG12613.1 - 0.032 13.9 0.2 0.089 12.5 0.0 1.9 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 KEG12613.1 - 0.066 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.14 KEG12613.1 - 0.07 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.15 KEG12613.1 - 0.074 13.1 0.0 6.9 6.7 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 KEG12613.1 - 0.076 12.8 0.4 2.1 8.1 0.1 2.8 3 0 0 3 3 2 0 ThiF family NAD_binding_9 PF13454.1 KEG12613.1 - 0.081 12.6 0.2 0.27 10.9 0.1 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding TLD PF07534.11 KEG12614.1 - 1e-11 45.0 0.0 2.2e-06 27.7 0.0 3.0 2 1 0 2 2 2 2 TLD SIS PF01380.17 KEG12615.1 - 7.7e-53 177.5 0.0 3.9e-28 97.6 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 KEG12615.1 - 3.2e-21 75.4 0.0 3.6e-15 55.5 0.0 2.4 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KEG12615.1 - 2.8e-17 62.9 0.0 9.9e-17 61.1 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KEG12615.1 - 4.7e-11 42.5 0.0 1.3e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 KEG12615.1 - 9e-08 31.1 0.0 1.7e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 KEG12615.1 - 0.00016 21.3 0.1 0.055 13.1 0.0 3.1 3 0 0 3 3 3 1 SIS domain Mob1_phocein PF03637.12 KEG12616.1 - 1.9e-62 210.0 0.1 2.2e-62 209.8 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family Thiolase_N PF00108.18 KEG12617.1 - 3.3e-64 216.4 0.1 4.4e-64 215.9 0.1 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KEG12617.1 - 2.3e-35 120.7 0.0 6.2e-35 119.3 0.0 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KEG12617.1 - 3.9e-07 29.8 1.5 5e-07 29.4 0.2 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.6 KEG12617.1 - 0.0021 16.5 0.1 0.0038 15.7 0.0 1.3 1 0 0 1 1 1 1 Stage V sporulation protein AD (SpoVAD) ACP_syn_III PF08545.5 KEG12617.1 - 0.017 14.7 2.6 0.042 13.5 0.2 2.5 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III NTPase_I-T PF01931.13 KEG12618.1 - 1.6e-63 213.3 0.0 1.8e-63 213.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF84 TSCPD PF12637.2 KEG12618.1 - 0.025 14.4 0.1 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 TSCPD domain TP_methylase PF00590.15 KEG12619.1 - 3.9e-19 69.1 0.0 6.8e-19 68.4 0.0 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Ribosomal_L36 PF00444.13 KEG12620.1 - 0.00011 22.0 0.3 0.00011 22.0 0.2 2.1 2 0 0 2 2 2 1 Ribosomal protein L36 PyrI_C PF02748.10 KEG12620.1 - 0.081 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Cmc1 PF08583.5 KEG12621.1 - 0.0068 16.1 2.9 0.014 15.1 2.0 1.5 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like zf-RING-like PF08746.6 KEG12621.1 - 0.1 12.6 0.5 0.18 11.8 0.3 1.4 1 0 0 1 1 1 0 RING-like domain DUF588 PF04535.7 KEG12623.1 - 0.056 13.0 0.0 0.068 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF588) Spectrin PF00435.16 KEG12624.1 - 0.02 15.1 0.6 0.045 14.0 0.4 1.5 1 0 0 1 1 1 0 Spectrin repeat DUF3647 PF12363.3 KEG12624.1 - 0.15 12.1 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Phage protein L51_S25_CI-B8 PF05047.11 KEG12625.1 - 1.2e-06 28.1 0.0 4.6e-06 26.2 0.0 2.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Glyco_tranf_2_5 PF13712.1 KEG12625.1 - 0.054 12.7 0.5 2.3 7.3 0.0 2.8 2 1 1 3 3 3 0 Glycosyltransferase like family SCP1201-deam PF14428.1 KEG12625.1 - 1 9.0 3.9 0.48 10.1 0.9 1.8 2 0 0 2 2 2 0 SCP1.201-like deaminase Pkinase PF00069.20 KEG12627.1 - 2.5e-46 157.9 0.0 4.5e-45 153.8 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG12627.1 - 1.3e-33 116.1 0.0 1.2e-30 106.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase PH_3 PF14593.1 KEG12627.1 - 1.2e-18 66.8 0.0 2e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 KEG12627.1 - 0.0047 15.9 0.0 0.007 15.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pex14_N PF04695.8 KEG12629.1 - 4.7 7.2 8.7 1.2 9.1 3.2 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region HEAT PF02985.17 KEG12633.1 - 4.3e-20 69.9 18.2 0.051 13.6 0.1 9.6 10 0 0 10 10 10 7 HEAT repeat HEAT_2 PF13646.1 KEG12633.1 - 1.3e-18 67.0 2.4 0.0022 18.2 0.0 5.7 2 2 4 6 6 6 4 HEAT repeats HEAT_EZ PF13513.1 KEG12633.1 - 0.00013 22.3 6.7 4.3 7.9 0.2 6.3 4 3 2 6 6 6 2 HEAT-like repeat Adaptin_N PF01602.15 KEG12633.1 - 0.0052 15.1 3.2 0.077 11.2 0.3 2.8 3 0 0 3 3 3 2 Adaptin N terminal region CLASP_N PF12348.3 KEG12633.1 - 0.0099 15.2 0.4 3.2 7.0 0.0 3.5 4 0 0 4 4 4 1 CLASP N terminal Cnd1 PF12717.2 KEG12633.1 - 0.014 15.2 2.1 2.2 8.0 0.2 3.7 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 KEG12633.1 - 0.023 15.0 7.9 0.07 13.5 0.2 4.8 5 1 2 7 7 7 0 Vacuolar 14 Fab1-binding region ATP-gua_Ptrans PF00217.14 KEG12635.1 - 1.3e-107 358.6 0.1 3.8e-107 357.1 0.0 1.7 2 0 0 2 2 2 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 KEG12635.1 - 5.7e-35 119.3 0.9 1.1e-34 118.3 0.1 1.9 2 0 0 2 2 2 1 ATP:guanido phosphotransferase, N-terminal domain DUF1342 PF07072.6 KEG12635.1 - 0.026 14.1 0.9 0.17 11.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1342) ABC2_membrane PF01061.19 KEG12636.1 - 1.5e-36 125.5 20.0 2.6e-36 124.7 13.9 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 KEG12636.1 - 1.6e-19 70.6 0.0 2.4e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KEG12636.1 - 8e-07 29.2 0.0 0.0019 18.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KEG12636.1 - 0.0018 18.6 0.0 0.0032 17.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KEG12636.1 - 0.0024 17.3 0.0 0.057 12.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KEG12636.1 - 0.0038 16.7 1.2 0.008 15.6 0.8 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 KEG12636.1 - 0.0055 15.9 0.1 0.11 11.7 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 KEG12636.1 - 0.011 14.9 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 KEG12636.1 - 0.022 14.8 0.0 0.064 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 KEG12636.1 - 0.027 13.5 0.0 0.66 8.9 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain PRK PF00485.13 KEG12636.1 - 0.028 13.9 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.17 KEG12636.1 - 0.033 13.0 0.1 0.076 11.8 0.0 1.5 1 1 0 1 1 1 0 NB-ARC domain AAA_17 PF13207.1 KEG12636.1 - 0.034 14.9 0.0 0.075 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 KEG12636.1 - 0.037 13.6 0.2 0.16 11.6 0.1 2.0 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 KEG12636.1 - 0.044 13.3 0.5 0.081 12.4 0.1 1.6 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 KEG12636.1 - 0.049 13.3 0.1 0.94 9.1 0.0 2.2 2 0 0 2 2 2 0 NTPase AAA_19 PF13245.1 KEG12636.1 - 0.074 12.8 0.1 0.21 11.3 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 KEG12636.1 - 0.14 12.3 0.0 0.8 9.9 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.1 KEG12636.1 - 0.14 12.0 0.1 0.34 10.8 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain TIP49 PF06068.8 KEG12636.1 - 0.19 10.4 0.1 0.27 9.8 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus DUF87 PF01935.12 KEG12636.1 - 0.36 10.6 0.8 0.67 9.7 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 SAP18 PF06487.7 KEG12637.1 - 0.053 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Sin3 associated polypeptide p18 (SAP18) Inositol_P PF00459.20 KEG12638.1 - 5.6e-29 101.2 0.2 1.8e-28 99.6 0.1 1.9 1 1 0 1 1 1 1 Inositol monophosphatase family MFS_1 PF07690.11 KEG12639.1 - 1.8e-17 63.0 29.7 1.6e-14 53.4 17.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily HTH_CodY PF08222.6 KEG12639.1 - 0.17 11.2 0.8 0.32 10.3 0.0 1.8 2 0 0 2 2 2 0 CodY helix-turn-helix domain MFS_1 PF07690.11 KEG12640.1 - 1.9e-10 40.0 32.9 1.1e-06 27.5 9.2 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF3331 PF11811.3 KEG12640.1 - 0.12 11.9 0.4 0.29 10.7 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3331) Pox_Ag35 PF03286.9 KEG12641.1 - 1.7 8.0 12.3 0.6 9.6 6.1 2.0 1 1 1 2 2 2 0 Pox virus Ag35 surface protein GET2 PF08690.5 KEG12641.1 - 9.5 5.3 11.8 1.8 7.7 5.4 1.7 1 1 1 2 2 2 0 GET complex subunit GET2 Nuc_sug_transp PF04142.10 KEG12643.1 - 5.5e-32 110.8 21.2 1.1e-31 109.7 11.1 2.8 1 1 1 2 2 2 1 Nucleotide-sugar transporter EamA PF00892.15 KEG12643.1 - 2.4e-10 40.5 25.5 2.4e-06 27.5 2.8 2.7 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 KEG12643.1 - 9.1e-05 21.5 20.1 0.0085 15.0 3.0 2.3 1 1 1 2 2 2 2 UAA transporter family EmrE PF13536.1 KEG12643.1 - 0.00068 19.8 4.3 0.00068 19.8 3.0 3.2 2 2 1 3 3 3 1 Multidrug resistance efflux transporter TPT PF03151.11 KEG12643.1 - 0.004 16.8 23.3 0.0046 16.6 4.6 2.7 2 1 0 2 2 2 2 Triose-phosphate Transporter family Herpes_UL87 PF03043.9 KEG12644.1 - 0.19 10.0 8.4 0.25 9.6 5.8 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family DUF1664 PF07889.7 KEG12644.1 - 3.6 7.3 8.8 5.8 6.7 2.8 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.14 KEG12644.1 - 7.8 4.2 17.0 1.9 6.2 8.8 1.6 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Mem_trans PF03547.13 KEG12645.1 - 3.9e-27 94.5 16.3 1.1e-26 93.0 11.3 1.6 1 1 0 1 1 1 1 Membrane transport protein Kinesin PF00225.18 KEG12646.1 - 0.00089 18.0 0.0 0.0012 17.6 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Epimerase PF01370.16 KEG12647.1 - 4.3e-68 229.2 0.0 5.5e-68 228.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KEG12647.1 - 3.5e-08 32.6 0.0 5e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KEG12647.1 - 1.6e-05 23.9 0.0 2.4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase_Csub PF13950.1 KEG12647.1 - 6e-05 22.9 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit NAD_binding_10 PF13460.1 KEG12647.1 - 0.00086 19.3 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KEG12647.1 - 0.0048 16.1 0.0 0.0095 15.2 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 KEG12647.1 - 0.0079 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Apc3 PF12895.2 KEG12648.1 - 2.6e-09 37.0 24.0 3.4e-07 30.3 3.5 5.1 3 1 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 KEG12648.1 - 1.6e-08 34.9 28.1 0.012 16.2 2.0 6.4 7 0 0 7 7 6 3 Tetratricopeptide repeat SRP72 PF08492.7 KEG12648.1 - 5.5e-07 29.8 0.4 5.5e-07 29.8 0.3 2.2 3 0 0 3 3 1 1 SRP72 RNA-binding domain TPR_19 PF14559.1 KEG12648.1 - 3.9e-06 27.1 29.6 0.45 10.8 0.8 7.6 6 1 2 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.1 KEG12648.1 - 0.00012 22.2 18.3 0.49 10.9 1.9 7.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_12 PF13424.1 KEG12648.1 - 0.0002 21.2 30.5 0.0023 17.8 2.7 5.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEG12648.1 - 0.00033 21.0 33.4 1.1 10.0 0.3 9.2 8 2 2 10 10 9 2 Tetratricopeptide repeat TPR_9 PF13371.1 KEG12648.1 - 0.014 15.2 1.4 0.014 15.2 0.9 5.4 3 1 2 6 6 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 KEG12648.1 - 0.06 13.1 10.7 0.1 12.4 0.8 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 KEG12648.1 - 0.3 11.0 13.9 1.6 8.7 1.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 KEG12648.1 - 0.35 10.5 25.8 3.2 7.4 8.4 5.2 5 1 0 5 5 5 0 TPR repeat TPR_1 PF00515.23 KEG12648.1 - 0.42 10.3 11.5 0.27 10.8 1.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KEG12648.1 - 0.58 10.0 8.8 4.7 7.1 0.1 3.5 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.12 KEG12648.1 - 1.4 9.0 25.6 0.65 10.0 1.6 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat ABC_tran PF00005.22 KEG12649.1 - 8.7e-44 149.1 0.0 1.3e-21 77.3 0.0 2.8 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KEG12649.1 - 2.2e-22 80.3 1.5 1.5e-08 35.0 0.3 4.1 2 2 0 3 3 3 3 AAA domain ABC_tran_2 PF12848.2 KEG12649.1 - 1.8e-19 69.3 2.7 1.8e-19 69.3 1.9 3.3 3 0 0 3 3 2 1 ABC transporter SMC_N PF02463.14 KEG12649.1 - 1.4e-10 40.7 1.1 0.0024 17.1 0.1 3.9 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KEG12649.1 - 1.5e-09 38.6 0.2 0.0022 18.8 0.0 3.5 3 1 1 4 4 3 2 AAA domain AAA_18 PF13238.1 KEG12649.1 - 1.9e-07 31.4 0.1 0.033 14.5 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA PF00004.24 KEG12649.1 - 3.4e-07 30.5 0.0 0.0052 16.9 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KEG12649.1 - 1e-06 28.7 0.0 0.025 14.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KEG12649.1 - 1.1e-06 28.0 0.0 0.061 12.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KEG12649.1 - 2.1e-06 28.2 4.3 0.081 13.2 0.0 3.4 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KEG12649.1 - 3.3e-06 27.1 0.9 0.01 15.8 0.0 3.1 2 2 0 2 2 2 2 AAA ATPase domain RNA_helicase PF00910.17 KEG12649.1 - 6.2e-06 26.3 0.0 0.024 14.8 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.1 KEG12649.1 - 7.5e-06 25.8 0.6 0.08 12.8 0.0 3.4 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.1 KEG12649.1 - 8.2e-06 25.3 0.0 0.072 12.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_14 PF13173.1 KEG12649.1 - 1.4e-05 24.9 0.0 1 9.2 0.0 3.6 3 0 0 3 3 3 2 AAA domain NACHT PF05729.7 KEG12649.1 - 3.2e-05 23.6 0.2 0.12 12.0 0.0 3.0 3 0 0 3 3 3 2 NACHT domain AAA_5 PF07728.9 KEG12649.1 - 3.6e-05 23.5 0.4 0.039 13.6 0.0 2.9 2 1 1 3 3 3 1 AAA domain (dynein-related subfamily) DUF258 PF03193.11 KEG12649.1 - 0.00015 20.9 0.0 0.6 9.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 KEG12649.1 - 0.00018 21.0 0.1 0.29 10.5 0.0 3.1 4 0 0 4 4 4 1 AAA-like domain AAA_13 PF13166.1 KEG12649.1 - 0.0002 19.9 0.6 0.61 8.4 0.0 3.7 3 1 0 3 3 3 1 AAA domain MobB PF03205.9 KEG12649.1 - 0.00021 21.0 0.2 0.073 12.7 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 KEG12649.1 - 0.00023 21.2 2.0 0.13 12.4 0.1 3.2 2 2 0 3 3 2 1 AAA domain AAA_15 PF13175.1 KEG12649.1 - 0.0003 19.9 0.0 0.87 8.5 0.0 3.7 4 0 0 4 4 4 1 AAA ATPase domain PduV-EutP PF10662.4 KEG12649.1 - 0.00059 19.3 0.0 0.26 10.7 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation UPF0079 PF02367.12 KEG12649.1 - 0.0008 19.0 0.1 0.011 15.4 0.0 2.6 3 0 0 3 3 2 1 Uncharacterised P-loop hydrolase UPF0079 Miro PF08477.8 KEG12649.1 - 0.00082 19.8 0.0 1.3 9.5 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein Arch_ATPase PF01637.13 KEG12649.1 - 0.0012 18.6 0.0 0.7 9.5 0.0 2.8 3 0 0 3 3 3 1 Archaeal ATPase AAA_19 PF13245.1 KEG12649.1 - 0.0013 18.3 0.0 0.067 12.9 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain SbcCD_C PF13558.1 KEG12649.1 - 0.0025 17.7 1.0 0.37 10.7 0.0 3.5 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 KEG12649.1 - 0.0029 17.5 0.3 2.4 8.1 0.0 3.0 2 2 0 2 2 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 KEG12649.1 - 0.0033 16.5 0.1 0.089 11.8 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin Mg_chelatase PF01078.16 KEG12649.1 - 0.006 15.7 0.0 4.1 6.5 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATP-synt_ab PF00006.20 KEG12649.1 - 0.006 16.0 0.0 0.92 8.9 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.1 KEG12649.1 - 0.01 15.4 0.5 1.2 8.6 0.0 3.0 3 0 0 3 3 2 0 AAA domain Rad17 PF03215.10 KEG12649.1 - 0.011 14.4 0.0 0.42 9.2 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein NTPase_1 PF03266.10 KEG12649.1 - 0.016 14.8 0.1 0.8 9.3 0.0 2.6 2 0 0 2 2 2 0 NTPase SRP54 PF00448.17 KEG12649.1 - 0.02 14.3 0.1 0.61 9.4 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ArgK PF03308.11 KEG12649.1 - 0.03 13.1 0.7 1.8 7.2 0.0 2.9 3 0 0 3 3 3 0 ArgK protein NB-ARC PF00931.17 KEG12649.1 - 0.03 13.1 0.0 4.7 5.9 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain G-alpha PF00503.15 KEG12649.1 - 0.034 12.8 0.1 3.9 6.0 0.0 2.4 2 1 0 2 2 2 0 G-protein alpha subunit IstB_IS21 PF01695.12 KEG12649.1 - 0.034 13.5 0.0 2 7.7 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein RuvB_N PF05496.7 KEG12649.1 - 0.061 12.3 0.1 0.47 9.4 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus Sigma54_activ_2 PF14532.1 KEG12649.1 - 0.13 12.3 0.0 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain cobW PF02492.14 KEG12649.1 - 0.25 10.7 3.6 1.9 7.8 0.0 2.7 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Cyclin_N PF00134.18 KEG12650.1 - 0.058 12.9 0.1 0.065 12.8 0.1 1.2 1 0 0 1 1 1 0 Cyclin, N-terminal domain PVL_ORF50 PF07768.6 KEG12651.1 - 0.79 9.7 4.8 0.25 11.3 1.4 1.6 2 0 0 2 2 2 0 PVL ORF-50-like family Vps53_N PF04100.7 KEG12652.1 - 1.4e-64 218.2 3.3 2e-64 217.8 2.3 1.2 1 0 0 1 1 1 1 Vps53-like, N-terminal COG7 PF10191.4 KEG12652.1 - 1.7e-05 22.9 1.7 3.1e-05 22.1 1.2 1.3 1 0 0 1 1 1 1 Golgi complex component 7 (COG7) Spc7 PF08317.6 KEG12652.1 - 0.036 12.7 1.9 0.064 11.9 1.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3626 PF12294.3 KEG12652.1 - 0.053 12.5 0.0 0.092 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3626) COG2 PF06148.6 KEG12652.1 - 0.053 13.3 2.9 0.13 12.1 0.8 2.5 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4043 PF13252.1 KEG12653.1 - 0.0039 16.2 0.1 0.0074 15.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4043) Arf PF00025.16 KEG12654.1 - 1.8e-41 141.3 0.0 2e-41 141.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KEG12654.1 - 1.3e-17 63.6 0.0 1.6e-17 63.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEG12654.1 - 9e-12 45.5 0.0 1.8e-11 44.5 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 KEG12654.1 - 1.5e-08 34.0 0.0 1.7e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KEG12654.1 - 1.8e-06 26.8 0.0 1.7e-05 23.6 0.0 2.1 2 1 0 2 2 2 1 G-protein alpha subunit SRPRB PF09439.5 KEG12654.1 - 4.3e-06 26.0 0.0 5.6e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KEG12654.1 - 7e-06 25.9 0.0 1.1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.7 KEG12654.1 - 3.7e-05 23.4 0.3 0.0023 17.6 0.2 2.2 1 1 0 1 1 1 1 NACHT domain GTP_EFTU PF00009.22 KEG12654.1 - 0.0011 18.3 0.0 0.016 14.6 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain cobW PF02492.14 KEG12654.1 - 0.0052 16.2 0.0 0.11 11.9 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 KEG12654.1 - 0.0066 16.7 0.0 0.0081 16.4 0.0 1.4 1 1 0 1 1 1 1 ABC transporter AAA_33 PF13671.1 KEG12654.1 - 0.012 15.4 0.1 0.016 15.0 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KEG12654.1 - 0.018 15.4 0.1 0.031 14.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KEG12654.1 - 0.03 13.8 0.0 0.052 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRP54 PF00448.17 KEG12654.1 - 0.034 13.5 0.5 0.065 12.6 0.1 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_17 PF13207.1 KEG12654.1 - 0.081 13.7 0.1 0.15 12.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 KEG12654.1 - 0.098 11.9 0.3 0.3 10.3 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B CAP_GLY PF01302.20 KEG12655.1 - 9e-20 70.1 0.0 1.4e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain TPR_12 PF13424.1 KEG12655.1 - 0.072 13.0 10.5 0.17 11.8 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Tox-GHH2 PF15635.1 KEG12655.1 - 9.1 6.7 13.3 3.7 7.9 0.4 2.8 2 1 1 3 3 3 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin 2 GAS PF13851.1 KEG12655.1 - 9.4 5.3 50.1 5.5 6.1 10.7 3.9 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding Dynein_light PF01221.13 KEG12657.1 - 1.1e-28 99.0 0.1 1.7e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.13 KEG12657.1 - 0.091 13.0 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Ground-like domain FKBP_C PF00254.23 KEG12658.1 - 1e-22 79.9 0.0 1.5e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_C PF00254.23 KEG12659.1 - 1.2e-06 28.4 0.0 2.4e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Clathrin PF00637.15 KEG12663.1 - 3.1e-11 43.0 1.9 0.0012 18.4 0.0 5.8 5 1 0 5 5 5 3 Region in Clathrin and VPS WD40 PF00400.27 KEG12663.1 - 2.6e-06 27.0 1.5 0.079 12.8 0.1 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KEG12663.1 - 6.2e-06 25.2 1.3 0.001 17.9 0.0 3.5 3 0 0 3 3 3 2 Coatomer WD associated region TPR_7 PF13176.1 KEG12663.1 - 2.2 8.3 9.3 8.8 6.4 0.0 5.4 7 0 0 7 7 7 0 Tetratricopeptide repeat LRR_4 PF12799.2 KEG12664.1 - 1.6e-16 59.5 13.8 2.8e-07 29.9 0.2 5.3 3 2 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG12664.1 - 6.6e-10 38.6 20.5 5.7e-06 25.9 2.9 5.1 3 3 3 6 6 6 6 Leucine rich repeat LRR_1 PF00560.28 KEG12664.1 - 1.5e-07 30.4 14.3 0.0081 16.0 0.1 7.0 8 0 0 8 8 8 1 Leucine Rich Repeat LRR_6 PF13516.1 KEG12664.1 - 4.2e-05 23.1 13.8 3.7 7.9 0.2 6.4 7 0 0 7 7 7 3 Leucine Rich repeat LRR_7 PF13504.1 KEG12664.1 - 0.0044 16.9 19.1 0.6 10.5 0.1 6.4 7 0 0 7 7 7 3 Leucine rich repeat B9-C2 PF07162.6 KEG12666.1 - 8.5e-41 139.5 0.0 1e-40 139.2 0.0 1.1 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Cpn60_TCP1 PF00118.19 KEG12668.1 - 3e-142 474.6 3.5 3.4e-142 474.4 2.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1338 PF07063.8 KEG12668.1 - 0.068 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1338) Dynein_heavy PF03028.10 KEG12669.1 - 8.3e-230 764.5 0.0 4.1e-171 570.5 0.0 2.4 2 0 0 2 2 2 2 Dynein heavy chain and region D6 of dynein motor DHC_N1 PF08385.7 KEG12669.1 - 2.9e-121 405.6 0.1 2.9e-121 405.6 0.1 4.5 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.2 KEG12669.1 - 2.2e-116 387.3 0.1 1.7e-115 384.3 0.1 2.5 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 DHC_N2 PF08393.8 KEG12669.1 - 8.5e-110 367.0 9.5 8.5e-110 367.0 6.6 3.5 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.2 KEG12669.1 - 2.6e-92 308.5 0.0 6.3e-92 307.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 KEG12669.1 - 8.5e-81 270.1 0.4 1.6e-80 269.1 0.3 1.5 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_7 PF12775.2 KEG12669.1 - 1.5e-80 270.1 1.3 4.7e-80 268.5 0.9 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 MT PF12777.2 KEG12669.1 - 2.2e-79 266.7 12.3 4.6e-79 265.6 8.5 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 KEG12669.1 - 2.6e-21 75.7 0.0 4.4e-07 29.6 0.0 4.9 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KEG12669.1 - 1.2e-07 31.8 6.6 0.028 14.4 0.0 6.3 5 1 1 6 6 5 2 AAA ATPase domain AAA PF00004.24 KEG12669.1 - 6.6e-07 29.5 0.3 0.068 13.3 0.0 4.3 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KEG12669.1 - 0.00026 20.6 0.7 13 5.5 0.0 3.8 3 0 0 3 3 3 0 Part of AAA domain AAA_18 PF13238.1 KEG12669.1 - 0.00032 21.0 1.7 6.3 7.1 0.0 6.3 5 0 0 5 5 5 1 AAA domain Mg_chelatase PF01078.16 KEG12669.1 - 0.0017 17.5 0.1 0.42 9.7 0.0 3.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KEG12669.1 - 0.0031 17.6 0.5 33 4.6 0.0 4.8 5 0 0 5 5 4 0 RNA helicase AAA_33 PF13671.1 KEG12669.1 - 0.0031 17.3 3.6 8.6 6.2 0.0 5.5 6 0 0 6 6 6 0 AAA domain AAA_17 PF13207.1 KEG12669.1 - 0.0051 17.6 1.7 0.61 10.9 0.0 5.2 4 0 0 4 4 3 1 AAA domain AAA_22 PF13401.1 KEG12669.1 - 0.0052 16.9 9.4 1.8 8.6 0.0 6.3 6 0 0 6 6 4 1 AAA domain ABC_tran PF00005.22 KEG12669.1 - 0.012 15.8 0.3 16 5.7 0.0 4.0 3 0 0 3 3 3 0 ABC transporter Reo_sigmaC PF04582.7 KEG12669.1 - 0.21 10.7 1.9 1 8.4 0.0 2.9 3 0 0 3 3 3 0 Reovirus sigma C capsid protein Viral_helicase1 PF01443.13 KEG12669.1 - 0.34 10.3 2.9 9.2 5.7 0.1 3.4 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase DNA_pol_A PF00476.15 KEG12670.1 - 6.6e-30 103.9 0.0 1.7e-29 102.6 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 KEG12670.1 - 0.0006 19.3 0.0 0.0038 16.7 0.0 2.2 2 0 0 2 2 2 1 3'-5' exonuclease TcpA PF05946.7 KEG12670.1 - 0.088 12.6 0.4 3.2 7.6 0.0 3.1 3 0 0 3 3 3 0 Toxin-coregulated pilus subunit TcpA SE PF08491.5 KEG12672.1 - 1e-61 208.1 0.0 1.6e-61 207.5 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 KEG12672.1 - 4e-06 26.1 0.1 0.022 13.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KEG12672.1 - 0.0043 17.0 0.2 0.017 15.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KEG12672.1 - 0.0077 15.1 0.4 0.88 8.4 0.0 2.9 3 0 0 3 3 3 1 Lycopene cyclase protein DAO PF01266.19 KEG12672.1 - 0.077 11.8 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KEG12672.1 - 0.11 12.3 0.1 0.49 10.2 0.0 1.8 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.13 KEG12672.1 - 0.19 9.9 0.0 0.3 9.3 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor CAF1 PF04857.15 KEG12673.1 - 9.3e-43 146.4 0.4 1.4e-42 145.8 0.3 1.3 1 0 0 1 1 1 1 CAF1 family ribonuclease HECT PF00632.20 KEG12676.1 - 4.5e-58 196.9 0.0 1.7e-57 195.0 0.0 1.9 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.23 KEG12676.1 - 1e-42 145.1 3.3 4.4e-20 72.0 0.0 4.0 3 0 0 3 3 3 3 SPRY domain Laminin_G_3 PF13385.1 KEG12676.1 - 7.1e-21 75.0 0.2 4.5e-09 36.7 0.0 3.4 3 1 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily UBA PF00627.26 KEG12676.1 - 0.058 13.2 0.2 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 UBA/TS-N domain Lectin_leg-like PF03388.8 KEG12677.1 - 1.6e-24 86.3 0.0 2.1e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family PEX11 PF05648.9 KEG12678.1 - 3.1e-07 29.9 0.7 6.1e-07 28.9 0.5 1.4 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) PI3_PI4_kinase PF00454.22 KEG12679.1 - 2.7e-58 197.2 0.1 5.7e-58 196.1 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 KEG12679.1 - 9.6e-58 195.8 4.2 2.1e-57 194.7 2.9 1.6 1 0 0 1 1 1 1 FAT domain DUF3385 PF11865.3 KEG12679.1 - 7.6e-37 126.7 0.8 7.5e-32 110.4 0.0 4.9 5 0 0 5 5 5 2 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 KEG12679.1 - 2.2e-26 91.8 2.9 1.7e-25 89.0 1.1 3.3 3 0 0 3 3 3 1 Rapamycin binding domain FATC PF02260.15 KEG12679.1 - 2.3e-16 58.9 0.7 5.5e-16 57.7 0.0 2.1 2 0 0 2 2 2 1 FATC domain HEAT_EZ PF13513.1 KEG12679.1 - 0.018 15.5 7.8 1.3e+02 3.2 0.0 7.5 6 1 1 7 7 7 0 HEAT-like repeat ParcG PF10274.4 KEG12679.1 - 0.052 13.4 3.9 9 6.1 0.1 4.6 4 1 1 5 5 5 0 Parkin co-regulated protein Ribosomal_L7Ae PF01248.21 KEG12680.1 - 2.7e-25 87.7 0.3 3.5e-25 87.3 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.1 KEG12680.1 - 0.025 14.3 0.1 0.084 12.6 0.1 2.0 1 1 0 1 1 1 0 PELOTA RNA binding domain DUF1512 PF07431.7 KEG12680.1 - 0.032 12.9 0.3 0.036 12.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) RRM_DME PF15628.1 KEG12680.1 - 0.099 12.3 0.0 0.56 9.9 0.0 1.8 2 0 0 2 2 2 0 RRM in Demeter SseB_C PF14581.1 KEG12680.1 - 0.1 12.4 0.3 0.24 11.2 0.2 1.6 1 1 0 1 1 1 0 SseB protein C-terminal domain FAM176 PF14851.1 KEG12682.1 - 0.54 9.9 7.7 0.78 9.4 0.1 3.5 3 0 0 3 3 3 0 FAM176 family Peptidase_S24 PF00717.18 KEG12683.1 - 7.8e-12 44.6 0.0 1.5e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase S24-like TctB PF07331.6 KEG12683.1 - 0.003 17.2 1.1 0.094 12.3 0.0 2.1 2 0 0 2 2 2 1 Tripartite tricarboxylate transporter TctB family Flavi_capsid PF01003.14 KEG12683.1 - 0.12 11.9 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 Flavivirus capsid protein C Clathrin PF00637.15 KEG12683.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Region in Clathrin and VPS Rad60-SLD PF11976.3 KEG12684.1 - 1.5e-25 88.6 0.1 2e-25 88.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KEG12684.1 - 2e-09 36.7 0.0 2.4e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family RHH_1 PF01402.16 KEG12684.1 - 0.022 14.6 0.0 0.073 12.9 0.0 1.8 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family TUG-UBL1 PF11470.3 KEG12684.1 - 0.05 13.5 0.0 0.067 13.1 0.0 1.2 1 0 0 1 1 1 0 GLUT4 regulating protein TUG DUF964 PF06133.6 KEG12685.1 - 0.03 14.3 1.8 0.079 12.9 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF964) MxiH PF09392.5 KEG12685.1 - 6.2 7.4 6.6 15 6.2 2.0 2.7 2 1 0 2 2 2 0 Type III secretion needle MxiH like PAT1 PF09770.4 KEG12685.1 - 7.1 4.7 13.1 8.5 4.4 9.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Myc_N PF01056.13 KEG12686.1 - 0.013 14.6 7.7 0.02 14.0 5.3 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Nop14 PF04147.7 KEG12686.1 - 0.03 12.2 4.5 0.033 12.1 3.2 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 KEG12686.1 - 0.041 12.3 6.3 0.047 12.1 4.4 1.2 1 0 0 1 1 1 0 Daxx Family BSP_II PF05432.6 KEG12686.1 - 0.042 13.1 17.5 0.1 11.8 12.1 1.7 1 1 0 1 1 1 0 Bone sialoprotein II (BSP-II) Paf1 PF03985.8 KEG12686.1 - 0.29 9.8 6.7 0.38 9.4 4.6 1.2 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.9 KEG12686.1 - 0.44 8.5 2.8 0.53 8.2 1.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 KEG12686.1 - 1.2 8.6 12.9 2 7.9 8.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin FAM176 PF14851.1 KEG12686.1 - 1.2 8.8 6.3 0.59 9.7 2.7 1.7 2 0 0 2 2 2 0 FAM176 family PBP1_TM PF14812.1 KEG12686.1 - 2.2 8.6 11.8 0.26 11.5 4.4 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pox_Ag35 PF03286.9 KEG12686.1 - 8.7 5.8 10.7 11 5.5 6.9 1.5 1 1 1 2 2 2 0 Pox virus Ag35 surface protein Pribosyltran_N PF13793.1 KEG12688.1 - 1.7e-23 82.5 0.1 1.4e-21 76.4 0.0 2.7 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KEG12688.1 - 1.4e-22 80.3 1.4 4.3e-20 72.2 0.1 2.9 3 0 0 3 3 3 2 Phosphoribosyl synthetase-associated domain SPX PF03105.14 KEG12688.1 - 8.7e-10 38.8 8.3 5.4e-05 23.1 0.1 3.1 2 1 1 3 3 3 2 SPX domain Pkinase PF00069.20 KEG12689.1 - 2.8e-46 157.8 0.0 1.5e-45 155.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG12689.1 - 6.5e-20 71.2 0.0 4e-16 58.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kelch_4 PF13418.1 KEG12689.1 - 7.4e-05 22.4 1.1 0.00053 19.6 0.0 2.9 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 KEG12689.1 - 9.4e-05 21.8 0.5 0.017 14.6 0.1 3.0 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 KEG12689.1 - 0.0018 18.3 1.0 0.15 12.2 0.0 3.5 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.1 KEG12689.1 - 0.0064 16.4 1.8 0.035 14.0 0.1 2.8 3 0 0 3 3 3 1 Kelch motif IncA PF04156.9 KEG12689.1 - 0.007 15.9 0.7 0.68 9.4 0.0 2.3 2 0 0 2 2 2 1 IncA protein DUF2173 PF09941.4 KEG12689.1 - 0.17 11.7 0.0 0.48 10.3 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2173) Adeno_E3_CR2 PF02439.10 KEG12689.1 - 0.38 10.3 6.1 0.06 12.8 0.7 2.4 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Pkinase PF00069.20 KEG12690.1 - 1.7e-39 135.5 0.0 3.2e-26 92.0 0.0 3.6 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEG12690.1 - 8.3e-19 67.6 0.0 1.4e-05 24.2 0.0 3.4 3 0 0 3 3 3 3 Protein tyrosine kinase Kelch_1 PF01344.20 KEG12690.1 - 8.8e-05 21.9 1.2 0.0031 17.0 0.1 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 KEG12690.1 - 0.00053 19.7 0.9 0.51 10.1 0.0 3.4 3 0 0 3 3 3 2 Galactose oxidase, central domain HECT PF00632.20 KEG12691.1 - 4.3e-39 134.5 0.0 9.5e-39 133.3 0.0 1.5 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.23 KEG12691.1 - 3.6e-13 49.6 0.1 1.2e-09 38.2 0.0 2.6 2 0 0 2 2 2 2 SPRY domain zf-RanBP PF00641.13 KEG12691.1 - 5.3e-05 22.2 1.6 5.3e-05 22.2 1.1 2.9 1 1 1 2 2 2 1 Zn-finger in Ran binding protein and others fn3 PF00041.16 KEG12692.1 - 4.7e-111 363.1 53.4 1.7e-05 24.8 0.1 39.8 38 7 0 38 38 38 27 Fibronectin type III domain Interfer-bind PF09294.5 KEG12692.1 - 1e-19 70.5 7.1 0.38 10.7 0.0 14.9 16 0 0 16 16 16 7 Interferon-alpha/beta receptor, fibronectin type III DUF2369 PF10179.4 KEG12692.1 - 0.5 9.4 5.3 5.6 5.9 0.0 5.1 7 0 0 7 7 7 0 Uncharacterised conserved protein (DUF2369) zf-primase PF09329.6 KEG12693.1 - 3.4e-12 45.7 0.3 8.4e-12 44.4 0.2 1.7 1 0 0 1 1 1 1 Primase zinc finger Mcm10 PF09332.6 KEG12693.1 - 0.00016 21.1 12.0 0.00016 21.1 8.3 2.4 2 1 0 2 2 2 1 Mcm10 replication factor DUF3882 PF07066.6 KEG12693.1 - 0.065 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Lactococcus phage M3 protein tRNA-synt_1g PF09334.6 KEG12693.1 - 0.21 10.1 0.5 0.33 9.5 0.4 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (M) Glyco_trans_4_4 PF13579.1 KEG12694.1 - 0.038 14.1 0.3 0.038 14.1 0.2 1.5 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain BTB_2 PF02214.17 KEG12694.1 - 0.039 14.1 0.0 0.069 13.3 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain Tim17 PF02466.14 KEG12695.1 - 9.2e-18 64.5 0.6 1.4e-17 63.8 0.4 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF3815 PF12821.2 KEG12695.1 - 0.025 14.5 0.9 0.048 13.6 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3815) NADHdh PF00146.16 KEG12696.1 - 4.2e-05 22.7 5.8 5.3e-05 22.4 4.0 1.1 1 0 0 1 1 1 1 NADH dehydrogenase Exo_endo_phos PF03372.18 KEG12697.1 - 1.9e-24 86.9 0.1 2.5e-24 86.5 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KEG12697.1 - 0.00073 19.1 0.0 0.0032 17.0 0.0 2.0 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase DUF998 PF06197.8 KEG12698.1 - 0.032 13.5 0.1 0.044 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF998) JAB PF01398.16 KEG12699.1 - 7.7e-22 77.1 0.0 1.5e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 KEG12699.1 - 2.2e-05 23.9 0.0 5.5e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Phage_tail_S PF05069.8 KEG12699.1 - 0.064 13.0 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 Phage virion morphogenesis family Fe-S_biosyn PF01521.15 KEG12700.1 - 1.2e-10 41.3 0.1 5.4e-07 29.5 0.1 2.2 2 0 0 2 2 2 2 Iron-sulphur cluster biosynthesis EF-hand_7 PF13499.1 KEG12701.1 - 1.8e-06 27.9 0.1 4.1e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 KEG12701.1 - 0.0083 15.7 0.1 0.28 10.8 0.1 2.4 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KEG12701.1 - 0.02 14.1 0.0 0.96 8.9 0.0 2.3 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.1 KEG12701.1 - 0.066 13.1 0.1 6.1 7.0 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain Methyltransf_18 PF12847.2 KEG12702.1 - 0.056 14.0 0.0 0.11 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Mem_trans PF03547.13 KEG12703.1 - 2.3e-18 65.7 18.5 6e-11 41.2 0.0 3.3 3 0 0 3 3 3 3 Membrane transport protein IL13 PF03487.8 KEG12703.1 - 0.025 14.3 1.0 1.8 8.3 0.0 2.8 2 0 0 2 2 2 0 Interleukin-13 Mito_fiss_reg PF05308.6 KEG12707.1 - 2.1 7.6 6.4 3.8 6.8 4.4 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 KEG12707.1 - 2.2 7.5 4.6 3.6 6.8 3.2 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal HEAT_EZ PF13513.1 KEG12715.1 - 2.5e-05 24.5 8.5 0.00049 20.5 0.0 6.1 7 1 0 7 7 7 1 HEAT-like repeat IBN_N PF03810.14 KEG12715.1 - 0.02 14.7 4.9 0.034 14.0 0.2 3.6 3 1 0 3 3 3 0 Importin-beta N-terminal domain Peptidase_M41 PF01434.13 KEG12716.1 - 2.3e-67 226.6 0.6 3.3e-67 226.0 0.4 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KEG12716.1 - 4e-42 143.5 0.0 1.2e-41 142.0 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KEG12716.1 - 1e-06 28.2 0.3 0.00052 19.4 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.9 KEG12716.1 - 2.1e-06 27.4 0.0 1.7e-05 24.5 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KEG12716.1 - 1.7e-05 24.9 1.0 0.0012 18.9 0.1 3.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEG12716.1 - 2.2e-05 24.5 0.3 0.0017 18.3 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 KEG12716.1 - 2.4e-05 23.5 0.0 0.00011 21.3 0.0 2.1 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 KEG12716.1 - 0.00021 21.0 0.4 0.007 16.0 0.0 2.7 3 0 0 3 3 3 1 NACHT domain AAA_17 PF13207.1 KEG12716.1 - 0.00021 22.0 0.0 0.00072 20.3 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 KEG12716.1 - 0.00037 20.3 0.0 0.0011 18.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KEG12716.1 - 0.00076 18.6 0.5 0.0039 16.2 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin IstB_IS21 PF01695.12 KEG12716.1 - 0.00081 18.8 0.0 0.0019 17.6 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 KEG12716.1 - 0.001 18.9 0.0 0.0029 17.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KEG12716.1 - 0.0012 17.6 0.0 0.0024 16.6 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_28 PF13521.1 KEG12716.1 - 0.0023 17.8 0.1 0.02 14.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KEG12716.1 - 0.0028 16.8 0.2 0.0056 15.8 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KEG12716.1 - 0.0045 16.7 0.0 0.016 14.9 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 KEG12716.1 - 0.0072 16.6 0.0 0.023 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KEG12716.1 - 0.0081 16.0 0.0 0.03 14.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_10 PF12846.2 KEG12716.1 - 0.0091 15.4 0.4 0.37 10.1 0.0 2.8 3 0 0 3 3 3 1 AAA-like domain Rad17 PF03215.10 KEG12716.1 - 0.012 14.3 0.0 0.021 13.5 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein ABC_tran PF00005.22 KEG12716.1 - 0.012 15.9 0.4 0.073 13.3 0.0 2.3 3 0 0 3 3 2 0 ABC transporter RNA_helicase PF00910.17 KEG12716.1 - 0.012 15.7 0.0 0.044 13.9 0.0 2.1 1 1 0 1 1 1 0 RNA helicase Dsl1_N PF11988.3 KEG12716.1 - 0.015 14.2 0.1 0.024 13.5 0.1 1.2 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 N terminal BAG PF02179.11 KEG12716.1 - 0.033 14.3 0.7 2.6 8.1 0.5 2.9 2 0 0 2 2 2 0 BAG domain NB-ARC PF00931.17 KEG12716.1 - 0.039 12.8 0.2 0.11 11.3 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain KaiC PF06745.8 KEG12716.1 - 0.065 12.3 0.7 1.1 8.3 0.0 3.0 4 0 0 4 4 4 0 KaiC Arch_ATPase PF01637.13 KEG12716.1 - 0.077 12.6 0.0 0.25 11.0 0.0 2.0 2 1 0 2 2 1 0 Archaeal ATPase ATP-synt_ab PF00006.20 KEG12716.1 - 0.089 12.2 0.0 0.28 10.6 0.0 1.5 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain FKBP_C PF00254.23 KEG12718.1 - 0.021 14.8 0.0 0.041 13.9 0.0 1.5 1 1 1 2 2 2 0 FKBP-type peptidyl-prolyl cis-trans isomerase Sex_peptide PF08138.6 KEG12718.1 - 0.092 12.6 0.9 0.15 11.9 0.6 1.3 1 0 0 1 1 1 0 Sex peptide (SP) family Thioredoxin PF00085.15 KEG12719.1 - 1.1e-19 70.0 0.0 1.3e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KEG12719.1 - 8.7e-06 25.9 0.3 5.8e-05 23.2 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KEG12719.1 - 3.6e-05 23.7 0.1 4.9e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.1 KEG12719.1 - 4.6e-05 23.4 0.1 0.025 14.7 0.1 2.2 1 1 1 2 2 2 2 Thioredoxin-like HyaE PF07449.6 KEG12719.1 - 0.01 15.6 0.0 0.017 15.0 0.0 1.5 1 1 0 1 1 1 0 Hydrogenase-1 expression protein HyaE TraF PF13728.1 KEG12719.1 - 0.013 14.9 0.0 0.016 14.6 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_9 PF14595.1 KEG12719.1 - 0.023 14.2 0.0 0.028 13.9 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Calsequestrin PF01216.12 KEG12719.1 - 0.092 11.4 0.0 0.096 11.4 0.0 1.1 1 0 0 1 1 1 0 Calsequestrin Pentapeptide PF00805.17 KEG12721.1 - 1.4e-09 36.9 4.3 0.0073 15.5 2.4 4.1 2 1 2 4 4 4 3 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 KEG12721.1 - 7.2e-08 32.1 9.2 2.6e-07 30.3 1.8 2.7 2 1 1 3 3 3 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 KEG12721.1 - 3.7e-05 23.5 11.0 0.0081 16.0 1.0 3.3 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) Rossmann-like PF10727.4 KEG12722.1 - 0.037 13.7 0.4 0.09 12.4 0.3 1.6 1 0 0 1 1 1 0 Rossmann-like domain 2-oxoacid_dh PF00198.18 KEG12724.1 - 3.1e-75 252.4 0.1 4.7e-75 251.8 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KEG12724.1 - 6.7e-16 57.6 0.1 1.4e-15 56.6 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KEG12724.1 - 1.8e-12 46.6 0.6 4.3e-12 45.4 0.4 1.7 1 0 0 1 1 1 1 e3 binding domain Gag_spuma PF03276.9 KEG12724.1 - 0.21 9.8 5.7 0.32 9.2 3.9 1.2 1 0 0 1 1 1 0 Spumavirus gag protein TFIIA PF03153.8 KEG12724.1 - 0.48 10.2 2.4 0.59 9.9 1.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Semialdhyde_dh PF01118.19 KEG12725.1 - 4.5e-05 23.7 0.0 0.00011 22.4 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KEG12725.1 - 0.0011 18.9 0.1 0.0068 16.4 0.0 2.4 3 0 0 3 3 3 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KEG12725.1 - 0.051 12.4 0.0 0.19 10.6 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein adh_short PF00106.20 KEG12725.1 - 0.098 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Methyltransf_11 PF08241.7 KEG12726.1 - 5.7e-14 52.3 0.1 8.7e-12 45.3 0.0 2.4 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEG12726.1 - 1.1e-13 51.2 0.0 1.5e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEG12726.1 - 1.1e-08 35.3 0.1 1e-07 32.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEG12726.1 - 1.5e-07 32.0 0.4 0.00035 21.1 0.0 3.0 3 1 1 4 4 4 2 Methyltransferase domain Methyltransf_12 PF08242.7 KEG12726.1 - 5.2e-07 30.0 0.2 2.7e-06 27.7 0.1 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEG12726.1 - 3.6e-06 26.6 0.1 3.9e-05 23.2 0.1 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEG12726.1 - 9.2e-05 22.4 0.2 0.00023 21.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 KEG12726.1 - 0.0037 16.3 0.0 0.099 11.7 0.0 2.2 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.6 KEG12726.1 - 0.013 14.2 0.0 0.16 10.6 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.13 KEG12726.1 - 0.015 14.4 0.0 0.033 13.3 0.0 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family TPR_2 PF07719.12 KEG12727.1 - 0.025 14.4 0.2 0.025 14.4 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat RRM_1 PF00076.17 KEG12729.1 - 1.4e-20 72.6 0.1 3.3e-20 71.4 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG12729.1 - 1.2e-10 41.1 0.0 2.1e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG12729.1 - 3.2e-10 39.6 0.0 5e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Reo_sigmaC PF04582.7 KEG12730.1 - 0.0038 16.4 7.5 0.36 9.9 0.2 4.3 2 1 0 3 3 3 1 Reovirus sigma C capsid protein TLV_coat PF00429.14 KEG12730.1 - 0.09 11.2 0.2 0.25 9.7 0.1 1.7 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) SpecificRecomb PF10136.4 KEG12730.1 - 0.27 9.2 3.1 0.75 7.7 2.2 1.7 1 0 0 1 1 1 0 Site-specific recombinase Androgen_recep PF02166.11 KEG12730.1 - 7.7 5.2 17.2 0.018 13.9 2.3 2.5 3 0 0 3 3 3 0 Androgen receptor NIF PF03031.13 KEG12731.1 - 1.8e-13 50.4 0.0 2.1e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 KEG12731.1 - 0.03 14.5 0.1 0.61 10.2 0.0 2.3 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase PSS PF03034.10 KEG12732.1 - 3.7e-104 348.0 6.8 6.1e-104 347.3 4.7 1.3 1 0 0 1 1 1 1 Phosphatidyl serine synthase Pex14_N PF04695.8 KEG12732.1 - 0.11 12.5 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Tmemb_18A PF09771.4 KEG12732.1 - 1.2 9.1 8.0 2.3 8.2 0.1 3.3 3 0 0 3 3 3 0 Transmembrane protein 188 Carb_kinase PF01256.12 KEG12733.1 - 1.4e-53 181.6 12.0 8.1e-53 179.1 3.7 3.0 2 1 0 2 2 2 1 Carbohydrate kinase YjeF_N PF03853.10 KEG12733.1 - 3.4e-48 163.4 0.3 8.5e-48 162.1 0.2 1.7 1 0 0 1 1 1 1 YjeF-related protein N-terminus Phos_pyr_kin PF08543.7 KEG12733.1 - 0.032 13.4 2.0 0.068 12.3 0.1 2.5 2 1 1 3 3 3 0 Phosphomethylpyrimidine kinase PAP_central PF04928.12 KEG12734.1 - 5.9e-83 277.5 0.0 8.2e-83 277.0 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 KEG12734.1 - 3e-24 85.3 0.0 4.7e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 KEG12734.1 - 0.00042 20.5 0.0 0.0009 19.5 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain DNA_pol_B_palm PF14792.1 KEG12734.1 - 0.0054 16.7 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm FYVE PF01363.16 KEG12735.1 - 3.4e-14 52.4 25.8 4e-14 52.2 15.0 2.9 2 1 0 2 2 2 1 FYVE zinc finger Ras PF00071.17 KEG12735.1 - 3.8e-13 49.1 0.0 6.2e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEG12735.1 - 7.4e-08 32.9 0.0 1.4e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 KEG12735.1 - 0.00019 21.5 0.0 0.00047 20.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEG12735.1 - 0.00066 19.7 0.1 0.0016 18.4 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain F-box-like PF12937.2 KEG12735.1 - 0.00079 19.1 0.1 0.0031 17.2 0.1 2.1 1 0 0 1 1 1 1 F-box-like NACHT PF05729.7 KEG12735.1 - 0.0012 18.5 0.1 0.0039 16.8 0.0 1.9 2 0 0 2 2 2 1 NACHT domain Arf PF00025.16 KEG12735.1 - 0.0046 16.2 0.0 0.0091 15.2 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF3760 PF12586.3 KEG12735.1 - 0.029 14.1 0.5 0.32 10.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3760) Arch_ATPase PF01637.13 KEG12735.1 - 0.072 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 KEG12735.1 - 0.072 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KEG12735.1 - 0.091 13.5 0.0 0.19 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KEG12735.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Pro_racemase PF05544.6 KEG12737.1 - 5.2e-124 413.2 0.1 5.9e-124 413.1 0.1 1.0 1 0 0 1 1 1 1 Proline racemase PhzC-PhzF PF02567.11 KEG12737.1 - 0.002 17.4 0.0 0.003 16.8 0.0 1.2 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein HTH_20 PF12840.2 KEG12737.1 - 0.079 12.7 0.7 0.8 9.5 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain CSD PF00313.17 KEG12738.1 - 8.2e-12 44.7 0.5 2e-05 24.2 0.1 4.1 4 0 0 4 4 4 3 'Cold-shock' DNA-binding domain OB_RNB PF08206.6 KEG12738.1 - 0.0093 15.4 0.7 1.9 8.0 0.1 2.8 2 0 0 2 2 2 2 Ribonuclease B OB domain WD40 PF00400.27 KEG12739.1 - 2.7e-08 33.3 13.3 0.033 14.0 0.3 5.4 6 0 0 6 6 6 4 WD domain, G-beta repeat Kinesin PF00225.18 KEG12740.1 - 3.3e-104 348.1 0.0 9e-104 346.7 0.0 1.8 1 0 0 1 1 1 1 Kinesin motor domain CENP-F_leu_zip PF10473.4 KEG12740.1 - 0.0017 18.1 10.5 0.0017 18.1 7.3 6.9 3 3 4 7 7 7 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 KEG12740.1 - 0.02 14.0 92.5 0.88 8.7 7.8 5.5 3 1 2 5 5 5 0 Growth-arrest specific micro-tubule binding HSP9_HSP12 PF04119.7 KEG12740.1 - 0.047 13.7 5.6 21 5.2 0.2 4.0 1 1 2 3 3 3 0 Heat shock protein 9/12 Reo_sigmaC PF04582.7 KEG12740.1 - 2.9 6.9 32.9 0.02 14.1 4.7 3.7 3 1 1 4 4 4 0 Reovirus sigma C capsid protein Ras PF00071.17 KEG12741.1 - 9.4e-24 83.6 0.0 1.7e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEG12741.1 - 2.6e-16 60.2 0.0 6e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEG12741.1 - 0.00013 21.2 0.0 0.00023 20.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.1 KEG12741.1 - 0.00036 20.5 0.8 0.00089 19.2 0.0 2.1 3 0 0 3 3 3 1 AAA ATPase domain MMR_HSR1 PF01926.18 KEG12741.1 - 0.005 16.7 0.0 0.017 15.1 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KEG12741.1 - 0.0058 16.0 0.1 0.14 11.5 0.1 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain NACHT PF05729.7 KEG12741.1 - 0.013 15.1 0.1 0.036 13.7 0.1 1.7 1 0 0 1 1 1 0 NACHT domain DUF258 PF03193.11 KEG12741.1 - 0.029 13.5 0.1 0.66 9.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 KEG12741.1 - 0.037 13.4 0.0 0.074 12.4 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain FtsK_SpoIIIE PF01580.13 KEG12741.1 - 0.049 13.1 0.0 0.14 11.5 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family Arch_ATPase PF01637.13 KEG12741.1 - 0.066 12.9 0.1 0.25 10.9 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase G-alpha PF00503.15 KEG12741.1 - 0.078 11.6 0.0 0.078 11.6 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Pox_A32 PF04665.7 KEG12741.1 - 0.1 11.8 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein ABC_tran PF00005.22 KEG12741.1 - 0.13 12.5 1.6 0.57 10.4 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.1 KEG12741.1 - 0.14 11.7 1.4 0.29 10.6 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KEG12741.1 - 0.57 10.4 5.5 19 5.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KEG12741.1 - 1.6 8.6 5.5 0.71 9.8 0.1 2.4 2 0 0 2 2 2 0 AAA domain DEAD PF00270.24 KEG12743.1 - 1.7e-37 128.5 0.0 2.8e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEG12743.1 - 7.8e-20 70.5 0.0 1.6e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 KEG12743.1 - 4e-16 58.2 0.2 8.2e-16 57.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Nt_Gln_amidase PF09764.4 KEG12744.1 - 4e-57 192.4 0.0 4.6e-57 192.2 0.0 1.0 1 0 0 1 1 1 1 N-terminal glutamine amidase Tautomerase_2 PF14552.1 KEG12744.1 - 0.035 14.1 0.0 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 Tautomerase enzyme DEAD PF00270.24 KEG12745.1 - 3.5e-45 153.5 0.1 1.3e-44 151.7 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEG12745.1 - 1.9e-23 82.1 0.1 3.9e-23 81.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain VHP PF02209.14 KEG12745.1 - 1 9.1 3.7 2.2 8.0 2.6 1.6 1 0 0 1 1 1 0 Villin headpiece domain DUF3675 PF12428.3 KEG12745.1 - 3.7 7.8 5.3 16 5.7 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) Ribosomal_S5_C PF03719.10 KEG12746.1 - 3.9e-16 58.0 0.2 6.2e-16 57.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 KEG12746.1 - 0.023 14.4 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S5, N-terminal domain MVP_shoulder PF11978.3 KEG12747.1 - 6.8e-45 151.7 0.0 1.2e-44 150.9 0.0 1.4 1 0 0 1 1 1 1 Shoulder domain Vault PF01505.13 KEG12747.1 - 2.5e-39 133.0 3.9 2.3e-13 49.9 0.1 4.8 4 0 0 4 4 4 4 Major Vault Protein repeat CBF PF03914.12 KEG12748.1 - 3e-34 117.8 0.8 1e-33 116.1 0.0 2.2 3 0 0 3 3 3 1 CBF/Mak21 family NOC3p PF07540.6 KEG12748.1 - 0.0022 18.2 0.1 0.0022 18.2 0.1 2.9 3 1 0 3 3 3 1 Nucleolar complex-associated protein DUF4187 PF13821.1 KEG12750.1 - 0.073 12.6 0.0 0.21 11.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) Ycf1 PF05758.7 KEG12750.1 - 3.8 5.1 8.2 5.9 4.4 5.7 1.2 1 0 0 1 1 1 0 Ycf1 GAS PF13851.1 KEG12752.1 - 1.1e-65 220.5 26.9 1.1e-65 220.5 18.7 3.1 2 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding z-alpha PF02295.12 KEG12752.1 - 0.16 11.7 1.4 11 5.8 0.1 2.6 2 0 0 2 2 2 0 Adenosine deaminase z-alpha domain CENP-F_leu_zip PF10473.4 KEG12752.1 - 4.4 7.1 56.5 0.24 11.2 9.5 3.8 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SET PF00856.23 KEG12753.1 - 0.00028 21.2 0.0 0.011 16.0 0.0 2.9 1 1 0 1 1 1 1 SET domain SNF2_N PF00176.18 KEG12757.1 - 9.7e-31 106.6 0.0 1.9e-30 105.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Tet_JBP PF12851.2 KEG12757.1 - 8.7e-27 93.4 0.1 1.7e-26 92.5 0.1 1.5 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Helicase_C PF00271.26 KEG12757.1 - 1.9e-13 50.0 0.1 4.1e-13 48.9 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEG12757.1 - 1.7e-07 30.8 0.0 3.2e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KEG12757.1 - 2.9e-05 23.9 0.0 0.00016 21.5 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KEG12757.1 - 0.14 12.3 0.0 0.43 10.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain SF-assemblin PF06705.6 KEG12758.1 - 5.8e-14 51.8 13.0 7.2e-14 51.5 9.0 1.1 1 0 0 1 1 1 1 SF-assemblin/beta giardin Phage_connect_1 PF05135.8 KEG12758.1 - 0.078 13.1 0.3 0.25 11.5 0.1 1.9 1 1 1 2 2 2 0 Phage gp6-like head-tail connector protein DUF1515 PF07439.6 KEG12758.1 - 0.23 11.3 5.2 1.7 8.4 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) DUF4611 PF15387.1 KEG12758.1 - 1.9 8.6 7.5 2.3 8.4 0.7 2.9 1 1 1 3 3 3 0 Domain of unknown function (DUF4611) Exonuc_VII_L PF02601.10 KEG12758.1 - 5.8 6.0 9.9 7.7 5.5 6.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit cNMP_binding PF00027.24 KEG12759.1 - 2e-08 33.8 0.2 0.019 14.7 0.0 4.0 3 1 0 3 3 3 2 Cyclic nucleotide-binding domain Arf PF00025.16 KEG12760.1 - 3.5e-06 26.3 0.0 9.2e-06 25.0 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 KEG12760.1 - 0.0037 17.7 0.0 0.0055 17.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Herpes_IE2_3 PF03361.9 KEG12760.1 - 0.01 15.1 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 0 Herpes virus intermediate/early protein 2/3 ATP_bind_1 PF03029.12 KEG12760.1 - 0.056 12.9 0.0 5.7 6.4 0.0 2.6 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 KEG12760.1 - 0.069 13.1 0.0 0.14 12.1 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain G-alpha PF00503.15 KEG12760.1 - 0.11 11.1 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_PrkA PF08298.6 KEG12760.1 - 0.12 11.0 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 PrkA AAA domain LRR_4 PF12799.2 KEG12762.1 - 1.5e-21 75.5 0.8 0.0023 17.5 0.0 6.7 4 3 4 8 8 8 7 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KEG12762.1 - 1.3e-16 58.7 11.5 0.001 18.9 0.1 8.7 8 1 1 9 9 9 4 Leucine Rich repeat LRR_8 PF13855.1 KEG12762.1 - 2.6e-16 59.0 9.5 8.8e-06 25.3 0.0 5.0 4 2 1 5 5 5 4 Leucine rich repeat LRR_1 PF00560.28 KEG12762.1 - 9e-13 46.3 11.1 0.63 10.2 0.0 9.1 7 2 0 7 7 7 5 Leucine Rich Repeat LRR_7 PF13504.1 KEG12762.1 - 0.00039 20.1 16.0 8 7.1 0.1 8.5 7 2 1 8 8 8 1 Leucine rich repeat DnaJ PF00226.26 KEG12764.1 - 5.9e-06 25.9 0.0 1.4e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain CH PF00307.26 KEG12765.1 - 6.7e-07 29.3 0.1 2.3e-06 27.5 0.0 2.0 1 0 0 1 1 1 1 Calponin homology (CH) domain ABG_transport PF03806.8 KEG12765.1 - 0.12 10.3 0.1 0.23 9.4 0.0 1.3 1 0 0 1 1 1 0 AbgT putative transporter family VGCC_beta4Aa_N PF12052.3 KEG12765.1 - 3.3 7.6 6.7 1.5 8.7 0.2 2.8 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal DUF972 PF06156.8 KEG12765.1 - 9.2 6.6 9.4 15 6.0 1.9 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF972) DnaJ PF00226.26 KEG12766.1 - 1.1e-14 53.9 0.4 2e-14 53.0 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain RNA_pol_Rbc25 PF08292.7 KEG12766.1 - 0.15 12.2 0.6 0.51 10.5 0.1 2.0 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 Nuc_deoxyrib_tr PF05014.10 KEG12766.1 - 0.3 10.9 2.2 0.5 10.2 0.0 2.3 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase DUF3731 PF12531.3 KEG12767.1 - 0.0077 15.7 0.1 0.017 14.6 0.0 1.6 2 0 0 2 2 2 1 DNA-K related protein IU_nuc_hydro PF01156.14 KEG12769.1 - 2.4e-74 250.4 0.1 2.9e-74 250.1 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase CAP59_mtransfer PF11735.3 KEG12769.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 MOZ_SAS PF01853.13 KEG12770.1 - 3.1e-62 209.1 0.0 4.8e-62 208.5 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 KEG12770.1 - 3.4e-10 39.4 0.1 7.7e-10 38.3 0.1 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-C2H2_4 PF13894.1 KEG12770.1 - 0.0044 17.2 0.9 0.013 15.8 0.6 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger Acetyltransf_1 PF00583.19 KEG12770.1 - 0.076 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family zf-C2H2 PF00096.21 KEG12770.1 - 0.099 13.0 2.9 0.25 11.7 2.0 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type SDA1 PF05285.7 KEG12771.1 - 1.3e-25 90.3 23.6 1.5e-25 90.2 16.3 1.0 1 0 0 1 1 1 1 SDA1 IQ PF00612.22 KEG12773.1 - 4e-06 25.9 53.7 0.031 13.8 0.2 9.2 10 0 0 10 10 10 7 IQ calmodulin-binding motif Inositol_P PF00459.20 KEG12774.1 - 1.9e-63 214.3 0.1 2.2e-63 214.1 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Peptidase_C65 PF10275.4 KEG12775.1 - 1.8e-60 204.3 0.0 2e-60 204.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.14 KEG12775.1 - 1.7e-08 35.0 0.1 0.00097 19.7 0.0 2.2 2 0 0 2 2 2 2 OTU-like cysteine protease HCV_NS5a_1b PF08301.8 KEG12775.1 - 0.15 12.4 0.1 0.31 11.4 0.1 1.5 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a domain 1b Cyclase_polyket PF04673.7 KEG12776.1 - 0.21 11.6 1.2 0.79 9.7 0.1 2.4 2 0 0 2 2 2 0 Polyketide synthesis cyclase DUF1664 PF07889.7 KEG12776.1 - 6 6.6 20.7 0.21 11.3 2.2 5.3 3 2 3 6 6 6 0 Protein of unknown function (DUF1664) Lipase_3 PF01764.20 KEG12777.1 - 0.00041 19.9 0.6 0.00093 18.8 0.4 1.6 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KEG12777.1 - 0.00069 19.3 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEG12777.1 - 0.00081 19.3 1.3 0.002 18.0 0.1 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KEG12777.1 - 0.013 15.7 0.1 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain DUF2974 PF11187.3 KEG12777.1 - 0.034 13.5 0.3 0.38 10.0 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2974) PGAP1 PF07819.8 KEG12777.1 - 0.039 13.5 0.3 0.068 12.7 0.2 1.3 1 0 0 1 1 1 0 PGAP1-like protein zf-ZPR1 PF03367.8 KEG12778.1 - 6.9e-108 356.9 0.5 3.9e-55 185.4 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain Zn-ribbon_8 PF09723.5 KEG12778.1 - 0.00012 21.9 6.7 3.7 7.5 0.0 4.5 4 0 0 4 4 4 1 Zinc ribbon domain HypA PF01155.14 KEG12778.1 - 0.0013 18.3 2.8 0.27 10.9 0.2 2.7 2 1 0 2 2 2 2 Hydrogenase expression/synthesis hypA family Zn_Tnp_IS1595 PF12760.2 KEG12778.1 - 0.0044 16.7 4.6 3 7.7 0.1 3.5 3 1 0 3 3 3 1 Transposase zinc-ribbon domain zf-DNA_Pol PF08996.5 KEG12778.1 - 0.0069 15.7 2.0 1.8 7.8 0.2 2.6 2 0 0 2 2 2 2 DNA Polymerase alpha zinc finger zf-ISL3 PF14690.1 KEG12778.1 - 0.0079 16.2 7.5 11 6.1 0.1 4.3 4 0 0 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DUF2387 PF09526.5 KEG12778.1 - 0.016 15.0 2.5 4.6 7.2 0.4 2.9 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) zf-ribbon_3 PF13248.1 KEG12778.1 - 0.026 13.7 12.5 0.85 8.9 0.2 4.3 4 0 0 4 4 4 0 zinc-ribbon domain DnaJ_CXXCXGXG PF00684.14 KEG12778.1 - 0.13 12.3 6.6 1.2 9.2 0.3 2.7 2 1 0 2 2 2 0 DnaJ central domain UPF0547 PF10571.4 KEG12778.1 - 0.2 11.3 0.2 0.2 11.3 0.1 4.2 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 zinc_ribbon_2 PF13240.1 KEG12778.1 - 0.22 11.0 11.4 1.2 8.6 0.5 4.1 4 0 0 4 4 4 0 zinc-ribbon domain Cys_rich_KTR PF14205.1 KEG12778.1 - 0.27 10.7 7.4 0.28 10.6 0.1 3.4 2 1 0 2 2 2 0 Cysteine-rich KTR zf-Di19 PF05605.7 KEG12778.1 - 0.36 10.9 6.5 1.5 8.9 0.1 3.8 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding Elf1 PF05129.8 KEG12778.1 - 0.43 10.3 8.7 7.8 6.2 0.1 3.5 2 2 2 4 4 4 0 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.1 KEG12778.1 - 0.45 10.8 8.9 7.6 6.9 0.4 3.2 2 1 1 3 3 3 0 Restriction alleviation protein Lar zf-RING_4 PF14570.1 KEG12778.1 - 0.49 10.0 4.7 7.7 6.1 0.1 3.5 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zinc-ribbons_6 PF07191.7 KEG12778.1 - 0.92 9.3 3.5 3.7 7.4 0.1 2.6 2 1 0 2 2 2 0 zinc-ribbons zf-C2H2_4 PF13894.1 KEG12778.1 - 0.95 9.9 7.2 41 4.8 0.0 4.1 5 0 0 5 5 3 0 C2H2-type zinc finger zf-AN1 PF01428.11 KEG12778.1 - 1 9.2 6.0 53 3.8 0.0 4.0 4 0 0 4 4 4 0 AN1-like Zinc finger Cys_rich_CPXG PF14255.1 KEG12778.1 - 1.5 8.7 8.8 2 8.2 0.2 3.9 4 0 0 4 4 4 0 Cysteine-rich CPXCG DUF329 PF03884.9 KEG12778.1 - 2.1 7.9 6.2 22 4.6 0.1 3.6 4 0 0 4 4 3 0 Domain of unknown function (DUF329) zf-LITAF-like PF10601.4 KEG12778.1 - 2.5 8.0 7.7 8.3 6.3 0.0 3.5 4 0 0 4 4 4 0 LITAF-like zinc ribbon domain DZR PF12773.2 KEG12778.1 - 4.9 7.0 11.9 24 4.8 2.2 3.4 2 2 1 3 3 3 0 Double zinc ribbon zf-Mss51 PF13824.1 KEG12778.1 - 5.1 7.0 11.6 15 5.5 0.3 3.8 3 1 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-H2C2_2 PF13465.1 KEG12778.1 - 8.5 6.8 11.3 12 6.3 0.1 3.8 4 0 0 4 4 4 0 Zinc-finger double domain zf-TFIIB PF13453.1 KEG12778.1 - 9.4 5.5 6.8 8.2 5.7 0.9 2.9 2 1 0 2 2 2 0 Transcription factor zinc-finger DUF3275 PF11679.3 KEG12779.1 - 0.086 12.4 0.6 0.1 12.2 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Cytochrom_C552 PF02335.10 KEG12779.1 - 0.14 10.8 0.0 0.14 10.8 0.0 1.0 1 0 0 1 1 1 0 Cytochrome c552 Phage_GPO PF05929.6 KEG12780.1 - 0.073 12.3 7.6 0.11 11.7 5.3 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Spc7 PF08317.6 KEG12780.1 - 0.18 10.4 19.4 0.035 12.7 10.6 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein Ly49 PF08391.5 KEG12780.1 - 0.72 10.0 7.3 0.11 12.6 1.2 2.3 1 1 2 3 3 3 0 Ly49-like protein, N-terminal region DUF342 PF03961.8 KEG12780.1 - 1 7.7 9.6 1.7 6.9 6.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) ERM PF00769.14 KEG12780.1 - 2.4 7.6 27.7 0.052 13.0 14.4 1.6 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Mgr1 PF08602.5 KEG12780.1 - 3.2 6.6 5.8 1.4 7.8 2.0 1.6 1 1 0 2 2 2 0 Mgr1-like, i-AAA protease complex subunit DUF2018 PF09442.5 KEG12780.1 - 4.5 7.9 7.0 8.5 7.0 0.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF2018) Syntaxin-6_N PF09177.6 KEG12780.1 - 5.5 7.4 15.4 7.4 7.0 1.9 3.2 2 1 1 3 3 3 0 Syntaxin 6, N-terminal fn1 PF00039.13 KEG12781.1 - 0.034 13.9 0.4 0.081 12.7 0.3 1.7 1 0 0 1 1 1 0 Fibronectin type I domain Ion_trans PF00520.26 KEG12782.1 - 8.1e-97 322.2 72.0 4.9e-29 101.0 5.7 5.0 6 0 0 6 6 6 4 Ion transport protein RabGAP-TBC PF00566.13 KEG12783.1 - 2.4e-20 72.9 1.6 4.3e-20 72.0 1.1 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Utp14 PF04615.8 KEG12783.1 - 0.064 11.4 0.2 0.086 10.9 0.1 1.1 1 0 0 1 1 1 0 Utp14 protein Abhydrolase_6 PF12697.2 KEG12784.1 - 3.3e-13 50.0 0.0 5e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEG12784.1 - 3.7e-06 26.7 0.0 8.1e-06 25.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEG12784.1 - 0.00014 21.5 0.0 0.00035 20.2 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ribosomal_L36e PF01158.13 KEG12786.1 - 6e-34 115.9 6.1 7.3e-34 115.6 4.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e DUF543 PF04418.7 KEG12787.1 - 2.4e-20 72.2 0.6 3e-20 71.9 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) ATP-synt_C PF00137.16 KEG12788.1 - 1.9e-17 62.9 12.0 2.8e-17 62.3 8.3 1.3 1 0 0 1 1 1 1 ATP synthase subunit C PCI PF01399.22 KEG12790.1 - 5.6e-12 45.8 0.4 1.7e-11 44.3 0.1 2.0 2 0 0 2 2 2 1 PCI domain Vps39_1 PF10366.4 KEG12790.1 - 0.0025 17.8 0.3 0.085 12.8 0.0 2.6 1 1 1 2 2 2 1 Vacuolar sorting protein 39 domain 1 Cpn60_TCP1 PF00118.19 KEG12790.1 - 0.018 13.7 0.6 1.4 7.4 0.1 2.3 2 0 0 2 2 2 0 TCP-1/cpn60 chaperonin family TMEM171 PF15471.1 KEG12792.1 - 0.023 13.4 2.5 0.029 13.1 1.7 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 CDK2AP PF09806.4 KEG12792.1 - 0.12 12.6 1.1 0.12 12.5 0.7 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Mito_fiss_reg PF05308.6 KEG12792.1 - 0.25 10.6 5.2 0.33 10.2 3.6 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 KEG12792.1 - 1.1 8.4 6.8 1.3 8.2 4.7 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Ras PF00071.17 KEG12794.1 - 6.8e-51 171.8 0.0 8.3e-51 171.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEG12794.1 - 1.5e-19 70.6 0.0 2.3e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEG12794.1 - 4.9e-10 38.9 0.0 6.8e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KEG12794.1 - 5.2e-08 32.5 0.1 1.9e-07 30.7 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KEG12794.1 - 2.8e-06 26.6 0.0 3.4e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KEG12794.1 - 0.00045 20.1 0.0 0.0007 19.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KEG12794.1 - 0.055 13.4 0.2 0.18 11.7 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.5 KEG12794.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Pex24p PF06398.6 KEG12795.1 - 0.074 11.8 1.1 0.12 11.1 0.8 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF3819 PF12842.2 KEG12796.1 - 1.7e-26 92.6 4.2 1.7e-26 92.6 2.9 2.7 2 0 0 2 2 1 1 Domain of unknown function (DUF3819) Med15 PF09606.5 KEG12796.1 - 0.0022 16.3 23.1 0.0022 16.3 16.0 3.3 3 0 0 3 3 3 2 ARC105 or Med15 subunit of Mediator complex non-fungal Hid1 PF12722.2 KEG12796.1 - 0.015 12.9 22.4 0.0017 16.1 2.2 2.4 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein PAT1 PF09770.4 KEG12796.1 - 0.021 13.0 72.7 0.019 13.2 13.0 3.1 3 0 0 3 3 3 0 Topoisomerase II-associated protein PAT1 OmpH PF03938.9 KEG12796.1 - 0.038 13.9 63.3 0.067 13.1 13.5 3.8 4 0 0 4 4 4 0 Outer membrane protein (OmpH-like) Suf PF05843.9 KEG12796.1 - 0.25 11.0 40.5 0.67 9.6 6.9 3.4 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) TFIIA PF03153.8 KEG12796.1 - 0.57 10.0 61.8 0.4 10.5 15.5 3.3 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit ABC2_membrane_2 PF12679.2 KEG12796.1 - 1.4 7.7 4.3 1.5 7.5 0.3 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein SET PF00856.23 KEG12796.1 - 1.6 8.9 6.0 7.3 6.8 1.0 3.0 3 0 0 3 3 3 0 SET domain eIF3_subunit PF08597.5 KEG12796.1 - 2.2 7.7 29.2 2.8 7.4 6.9 2.7 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit GAGA_bind PF06217.7 KEG12796.1 - 2.2 8.1 36.3 1.1 9.1 5.7 3.3 3 0 0 3 3 3 0 GAGA binding protein-like family NARP1 PF12569.3 KEG12796.1 - 3.1 6.4 31.7 3.6 6.2 7.4 2.7 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 SAGA-Tad1 PF12767.2 KEG12796.1 - 5.6 6.5 35.0 0.12 12.0 4.4 2.9 3 0 0 3 3 3 0 Transcriptional regulator of RNA polII, SAGA, subunit SPX PF03105.14 KEG12796.1 - 6.9 6.3 24.8 0.9 9.2 3.7 2.8 3 0 0 3 3 3 0 SPX domain DUF4175 PF13779.1 KEG12796.1 - 9.5 3.7 82.1 0.051 11.2 18.5 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4175) Not1 PF04054.10 KEG12797.1 - 1.9e-115 385.7 3.3 3.1e-115 385.0 2.3 1.3 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 Spt20 PF12090.3 KEG12797.1 - 0.045 13.0 2.0 0.12 11.7 1.4 1.7 1 0 0 1 1 1 0 Spt20 family MarR PF01047.17 KEG12797.1 - 0.053 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 MarR family RAB3GAP2_N PF14655.1 KEG12797.1 - 5.4 5.8 9.1 33 3.3 0.0 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PHF5 PF03660.9 KEG12798.1 - 2.3e-32 111.2 11.4 2.4e-32 111.1 7.9 1.0 1 0 0 1 1 1 1 PHF5-like protein Tnp_zf-ribbon_2 PF13842.1 KEG12798.1 - 0.028 14.8 1.3 0.028 14.8 0.9 3.3 4 1 0 4 4 4 0 DDE_Tnp_1-like zinc-ribbon zf-RING_2 PF13639.1 KEG12799.1 - 1.7e-13 50.1 10.7 4e-13 48.9 7.5 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KEG12799.1 - 1.3e-08 34.8 5.5 2.9e-08 33.7 3.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KEG12799.1 - 3.9e-06 26.7 10.6 8.2e-06 25.7 7.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KEG12799.1 - 8.6e-06 25.5 2.9 1.9e-05 24.4 2.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 KEG12799.1 - 3.2e-05 23.5 10.7 5.4e-05 22.7 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEG12799.1 - 4.6e-05 23.0 9.5 7.7e-05 22.3 6.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KEG12799.1 - 6.8e-05 22.4 8.8 0.00012 21.6 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KEG12799.1 - 0.016 14.9 7.1 0.03 14.0 4.9 1.5 1 0 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.3 KEG12799.1 - 0.089 12.7 6.0 0.37 10.7 4.2 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain Rtf2 PF04641.7 KEG12799.1 - 0.14 11.2 0.3 0.24 10.5 0.2 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger zf-C3HC4_4 PF15227.1 KEG12799.1 - 1.4 8.8 6.5 1.3 8.9 3.1 2.1 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KEG12799.1 - 2.4 7.8 8.4 4.2 7.0 5.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 KEG12799.1 - 7.3 6.7 10.9 18 5.5 7.6 1.6 1 0 0 1 1 1 0 RING-variant domain ENTH PF01417.15 KEG12801.1 - 2.2e-07 30.7 0.0 0.028 14.3 0.0 2.4 2 0 0 2 2 2 2 ENTH domain ANTH PF07651.11 KEG12801.1 - 0.00023 19.9 0.1 0.074 11.7 0.0 2.6 3 0 0 3 3 3 2 ANTH domain PRTase_2 PF15609.1 KEG12801.1 - 0.0041 16.4 0.1 0.0094 15.2 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase ATP-grasp_2 PF08442.5 KEG12802.1 - 9.6e-63 211.2 0.7 1.6e-62 210.4 0.5 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 KEG12802.1 - 2.3e-24 85.7 0.5 1.3e-23 83.3 0.1 2.2 2 0 0 2 2 2 1 CoA-ligase GARS_A PF01071.14 KEG12802.1 - 0.0049 16.4 0.8 0.02 14.4 0.6 2.1 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF4131 PF13567.1 KEG12803.1 - 0.31 10.4 2.0 0.73 9.2 1.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Bromodomain PF00439.20 KEG12806.1 - 2.5e-18 65.7 0.0 4.3e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 Bromodomain TFIIA PF03153.8 KEG12806.1 - 0.055 13.3 26.4 0.06 13.2 18.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Astro_capsid PF03115.9 KEG12806.1 - 0.27 9.4 10.0 0.35 9.0 6.9 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor CDC45 PF02724.9 KEG12806.1 - 4.8 5.0 25.6 6.4 4.6 17.7 1.3 1 0 0 1 1 1 0 CDC45-like protein GTP1_OBG PF01018.17 KEG12807.1 - 8e-36 123.0 5.0 1.1e-35 122.5 3.5 1.2 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.18 KEG12807.1 - 2.5e-16 59.6 0.0 4.3e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KEG12807.1 - 1.6e-06 27.4 0.0 1.2e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.16 KEG12807.1 - 0.033 13.4 0.0 0.3 10.3 0.0 2.3 2 1 0 2 2 2 0 ADP-ribosylation factor family GTP_EFTU PF00009.22 KEG12807.1 - 0.049 13.0 0.0 12 5.2 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DSHCT PF08148.7 KEG12808.1 - 5.9e-53 178.7 0.3 5.9e-53 178.7 0.2 2.1 3 0 0 3 3 3 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.1 KEG12808.1 - 6.2e-51 173.1 0.0 1.2e-50 172.2 0.0 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.24 KEG12808.1 - 1.1e-24 86.8 0.7 4.9e-24 84.7 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEG12808.1 - 7.2e-07 28.9 0.0 2.1e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEG12808.1 - 0.00029 20.7 0.0 0.00092 19.0 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KEG12808.1 - 0.00084 19.0 0.0 0.0025 17.5 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain PhoH PF02562.11 KEG12808.1 - 0.0025 17.0 0.0 0.0069 15.6 0.0 1.7 1 0 0 1 1 1 1 PhoH-like protein Zot PF05707.7 KEG12808.1 - 0.0029 17.0 0.0 0.014 14.8 0.0 2.0 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) Arch_ATPase PF01637.13 KEG12808.1 - 0.0072 16.0 1.0 0.013 15.1 0.0 1.8 2 0 0 2 2 2 1 Archaeal ATPase DUF4122 PF13498.1 KEG12808.1 - 0.025 13.9 1.4 0.046 13.0 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4122) T2SE PF00437.15 KEG12808.1 - 0.029 13.2 0.0 0.072 11.9 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein CobA_CobO_BtuR PF02572.10 KEG12808.1 - 0.032 13.8 0.0 0.084 12.4 0.0 1.7 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP DUF1664 PF07889.7 KEG12808.1 - 0.073 12.8 0.7 0.61 9.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) RMMBL PF07521.7 KEG12808.1 - 0.08 12.7 0.0 2.3 8.1 0.0 2.7 2 0 0 2 2 2 0 RNA-metabolising metallo-beta-lactamase FlxA PF14282.1 KEG12808.1 - 0.63 10.0 1.8 0.87 9.5 0.3 1.9 2 0 0 2 2 1 0 FlxA-like protein RNase_PH PF01138.16 KEG12809.1 - 3.5e-27 95.3 1.1 5.3e-27 94.7 0.8 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KEG12809.1 - 0.018 14.9 0.1 0.033 14.1 0.1 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Adap_comp_sub PF00928.16 KEG12810.1 - 1.6e-53 181.4 0.0 2e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KEG12810.1 - 0.00023 20.9 0.9 0.00051 19.7 0.6 1.6 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RRM_1 PF00076.17 KEG12811.1 - 2e-09 36.9 0.0 2.6e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG12811.1 - 5e-07 29.6 0.0 6.6e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG12811.1 - 7e-06 25.8 0.0 9.6e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF619 PF04768.8 KEG12811.1 - 0.12 11.7 0.2 0.96 8.8 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF619) Peroxin-22 PF12827.2 KEG12812.1 - 0.03 14.0 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family Cullin PF00888.17 KEG12813.1 - 5.2e-71 239.9 2.6 5.2e-71 239.9 1.8 1.3 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 KEG12813.1 - 3.1e-15 55.7 0.0 8.7e-15 54.3 0.0 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain TrmB PF01978.14 KEG12813.1 - 0.0033 17.1 0.0 1 9.1 0.0 2.8 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB Tau95 PF09734.4 KEG12813.1 - 0.015 14.6 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit LexA_DNA_bind PF01726.11 KEG12813.1 - 0.045 13.3 0.0 9.4 5.8 0.0 3.3 2 1 0 2 2 2 0 LexA DNA binding domain Fibrillarin PF01269.12 KEG12814.1 - 2.9e-106 353.5 0.0 3.3e-106 353.3 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 KEG12814.1 - 4.1e-05 23.2 0.0 6.5e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 KEG12814.1 - 0.0068 15.9 0.0 0.012 15.1 0.0 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Gp37_Gp68 PF07505.6 KEG12816.1 - 0.36 9.9 2.6 0.45 9.6 1.8 1.1 1 0 0 1 1 1 0 Phage protein Gp37/Gp68 RabGAP-TBC PF00566.13 KEG12817.1 - 5.7e-09 35.7 1.1 1.4e-08 34.4 0.8 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain WD40 PF00400.27 KEG12817.1 - 0.098 12.5 0.5 6 6.9 0.0 3.7 3 0 0 3 3 3 0 WD domain, G-beta repeat CH PF00307.26 KEG12818.1 - 1e-06 28.7 0.0 2e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KEG12818.1 - 0.0002 20.9 0.0 0.0009 18.8 0.0 2.0 2 0 0 2 2 2 1 CAMSAP CH domain PIG-P PF08510.7 KEG12819.1 - 6e-32 109.9 2.4 6.8e-32 109.7 1.6 1.0 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.7 KEG12819.1 - 0.12 12.7 7.7 0.18 12.0 5.3 1.3 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) RE_SacI PF09566.5 KEG12820.1 - 0.00043 19.3 0.8 0.001 18.1 0.4 1.7 1 1 0 1 1 1 1 SacI restriction endonuclease FAST_1 PF06743.10 KEG12820.1 - 0.024 14.3 0.2 2.3 8.0 0.0 2.8 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 Cep57_CLD PF14073.1 KEG12820.1 - 0.064 13.0 1.8 0.13 12.0 1.3 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 FAST_1 PF06743.10 KEG12821.1 - 5.9e-06 25.8 0.1 0.15 11.8 0.0 4.5 2 1 3 5 5 5 4 FAST kinase-like protein, subdomain 1 DUF1749 PF08538.5 KEG12822.1 - 9.5e-13 47.7 0.0 1.3e-12 47.2 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 KEG12822.1 - 3.7e-09 36.7 0.0 5.4e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEG12822.1 - 0.15 11.8 0.0 0.31 10.7 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family PPR_2 PF13041.1 KEG12824.1 - 7.8e-46 153.8 9.1 7.8e-15 54.5 0.1 5.7 1 1 5 6 6 6 6 PPR repeat family PPR_3 PF13812.1 KEG12824.1 - 3e-38 126.8 6.1 3e-08 33.3 0.0 6.3 6 0 0 6 6 6 6 Pentatricopeptide repeat domain PPR PF01535.15 KEG12824.1 - 9.9e-31 103.5 0.2 5.4e-06 26.0 0.0 6.2 6 0 0 6 6 6 6 PPR repeat PPR_1 PF12854.2 KEG12824.1 - 7.5e-25 86.1 1.1 5.1e-05 22.6 0.0 5.5 5 0 0 5 5 5 5 PPR repeat TPR_14 PF13428.1 KEG12824.1 - 8.5e-07 29.0 1.2 0.36 11.5 0.0 5.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEG12824.1 - 2.7e-05 23.6 0.0 0.88 9.5 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEG12824.1 - 0.019 15.2 0.0 4.8 7.5 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 KEG12824.1 - 0.055 13.4 0.5 2.2 8.2 0.0 3.4 4 2 0 4 4 4 0 Tetratricopeptide repeat XdhC_CoxI PF02625.11 KEG12824.1 - 0.074 12.6 0.0 0.24 11.0 0.0 1.8 1 1 0 1 1 1 0 XdhC and CoxI family Clathrin PF00637.15 KEG12824.1 - 0.086 12.4 0.0 6.6 6.3 0.0 3.2 1 1 0 1 1 1 0 Region in Clathrin and VPS TPR_16 PF13432.1 KEG12824.1 - 0.088 13.5 0.2 7.7 7.3 0.0 3.5 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEG12824.1 - 0.67 10.5 3.9 46 4.7 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat WD40 PF00400.27 KEG12825.1 - 1.5e-49 164.1 26.5 2.9e-10 39.6 0.7 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KEG12825.1 - 0.00043 18.5 3.0 0.035 12.2 0.1 3.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KEG12825.1 - 0.093 11.4 0.0 3.6 6.2 0.0 2.9 2 1 1 3 3 3 0 Nup133 N terminal like LRR_4 PF12799.2 KEG12828.1 - 5.2e-46 153.6 32.1 8.1e-06 25.3 0.3 13.8 5 4 8 16 16 16 15 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KEG12828.1 - 4.4e-30 100.3 53.4 0.026 14.5 0.0 20.3 18 2 2 20 20 20 11 Leucine Rich repeat LRR_8 PF13855.1 KEG12828.1 - 6e-30 102.7 49.5 0.0011 18.6 0.0 11.9 4 4 10 14 14 14 13 Leucine rich repeat LRR_1 PF00560.28 KEG12828.1 - 2.2e-09 36.0 59.7 1.1 9.5 0.6 18.3 17 5 0 17 17 17 3 Leucine Rich Repeat LRR_7 PF13504.1 KEG12828.1 - 8.5e-05 22.1 62.4 5.2 7.7 0.2 18.4 20 1 0 20 20 20 3 Leucine rich repeat LRR_5 PF13306.1 KEG12828.1 - 0.0012 18.5 2.1 0.29 10.8 0.0 4.1 3 2 1 4 4 4 1 Leucine rich repeats (6 copies) 2_5_RNA_ligase2 PF13563.1 KEG12830.1 - 1.4e-05 24.8 0.1 0.00015 21.4 0.0 2.1 1 1 1 2 2 2 2 2'-5' RNA ligase superfamily Phage_lambd_GpG PF06894.6 KEG12830.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage lambda minor tail protein (GpG) NDUF_B6 PF09782.4 KEG12830.1 - 0.19 11.5 1.9 2.6 7.8 0.0 2.6 2 1 1 3 3 3 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit MtN3_slv PF03083.11 KEG12831.1 - 3.1e-32 110.2 8.1 4.5e-17 61.6 1.0 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.9 KEG12831.1 - 0.022 14.2 0.1 0.022 14.2 0.0 4.1 5 1 1 6 6 6 0 PQ loop repeat DUF2919 PF11143.3 KEG12831.1 - 2.3 8.0 7.4 20 5.0 1.2 3.3 1 1 3 4 4 4 0 Protein of unknown function (DUF2919) NPV_P10 PF05531.7 KEG12832.1 - 0.05 13.8 0.1 0.079 13.2 0.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein CHAP PF05257.11 KEG12833.1 - 3.4e-16 59.0 0.1 4.1e-16 58.7 0.1 1.2 1 0 0 1 1 1 1 CHAP domain FtsX PF02687.16 KEG12834.1 - 3.9e-27 94.4 34.2 2.4e-15 56.3 6.0 5.0 5 0 0 5 5 5 2 FtsX-like permease family P4Ha_N PF08336.6 KEG12835.1 - 0.11 12.3 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Aldose_epim PF01263.15 KEG12836.1 - 1.7e-51 175.1 0.0 2e-51 174.9 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase ABC_tran PF00005.22 KEG12839.1 - 2.6e-30 105.4 0.0 4.5e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 KEG12839.1 - 4.2e-26 91.4 17.1 4.2e-26 91.4 11.8 3.8 5 0 0 5 5 5 1 ABC-2 type transporter AAA_21 PF13304.1 KEG12839.1 - 4.9e-07 30.0 0.0 0.014 15.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KEG12839.1 - 2.1e-05 24.5 0.1 4.6e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ABC2_membrane_3 PF12698.2 KEG12839.1 - 7.1e-05 22.0 12.6 7.1e-05 22.0 8.8 2.6 3 1 1 4 4 4 1 ABC-2 family transporter protein DUF258 PF03193.11 KEG12839.1 - 0.00064 18.9 0.2 0.0022 17.2 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SbcCD_C PF13558.1 KEG12839.1 - 0.00075 19.3 0.6 0.041 13.8 0.0 3.2 3 1 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 KEG12839.1 - 0.001 18.5 0.0 0.0024 17.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KEG12839.1 - 0.0059 16.7 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 KEG12839.1 - 0.018 13.7 0.0 0.028 13.1 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_23 PF13476.1 KEG12839.1 - 0.021 15.1 0.1 0.042 14.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KEG12839.1 - 0.024 15.4 0.0 0.05 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KEG12839.1 - 0.028 13.8 0.0 0.057 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KEG12839.1 - 0.038 13.7 0.1 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain cobW PF02492.14 KEG12839.1 - 0.079 12.3 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 KEG12839.1 - 0.086 12.7 0.7 0.17 11.8 0.5 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KEG12839.1 - 0.096 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 KEG12839.1 - 0.11 12.0 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SMC_N PF02463.14 KEG12839.1 - 0.11 11.6 0.0 0.27 10.4 0.0 1.6 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 KEG12839.1 - 0.15 12.3 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ADH_N PF08240.7 KEG12840.1 - 2.6e-29 101.1 5.1 2.6e-29 101.1 3.6 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEG12840.1 - 1.3e-26 92.7 0.1 2e-26 92.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KEG12840.1 - 8e-05 21.8 0.2 0.00013 21.2 0.2 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 KEG12840.1 - 0.0033 17.2 0.4 0.0056 16.5 0.3 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.16 KEG12840.1 - 0.028 13.9 0.5 0.063 12.8 0.3 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Ribonucleas_3_3 PF14622.1 KEG12841.1 - 0.0046 16.9 0.0 0.34 10.8 0.0 2.8 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 KEG12841.1 - 0.016 15.6 0.1 0.31 11.5 0.1 2.7 1 1 0 1 1 1 0 Ribonuclease III domain DP PF08781.5 KEG12841.1 - 0.25 11.0 0.0 0.54 9.9 0.0 1.5 1 0 0 1 1 1 0 Transcription factor DP DUF4515 PF14988.1 KEG12842.1 - 0.054 13.1 0.1 0.09 12.4 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4515) DUF2379 PF09543.5 KEG12842.1 - 0.096 12.6 0.4 0.18 11.7 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2379) Adeno_terminal PF02459.10 KEG12845.1 - 0.086 11.0 1.1 0.14 10.3 0.8 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein PBP PF01161.15 KEG12846.1 - 5e-09 36.1 0.2 1.6e-08 34.4 0.0 1.9 2 0 0 2 2 2 1 Phosphatidylethanolamine-binding protein PUF PF00806.14 KEG12848.1 - 1e-21 75.0 0.0 0.021 14.3 0.0 8.8 8 1 1 9 9 9 4 Pumilio-family RNA binding repeat Striatin PF08232.7 KEG12848.1 - 0.0025 18.1 6.7 0.0025 18.1 4.6 2.0 2 0 0 2 2 2 1 Striatin family DUF1414 PF07208.6 KEG12848.1 - 0.0029 17.2 0.0 0.015 15.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1414) Vfa1 PF08432.5 KEG12848.1 - 0.012 15.6 7.0 0.012 15.6 4.8 1.7 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.9 KEG12848.1 - 0.045 11.8 9.4 0.076 11.0 6.5 1.3 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.6 KEG12848.1 - 0.085 10.9 2.2 0.13 10.3 1.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sporozoite_P67 PF05642.6 KEG12848.1 - 0.42 8.4 7.0 0.62 7.8 4.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Fmp27_WPPW PF10359.4 KEG12848.1 - 2 6.7 9.7 0.44 8.9 4.2 1.6 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain HSP90 PF00183.13 KEG12848.1 - 2.3 6.5 13.1 3.6 5.8 9.1 1.2 1 0 0 1 1 1 0 Hsp90 protein TRAP_alpha PF03896.11 KEG12848.1 - 2.5 7.0 9.8 4.3 6.2 6.8 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DDHD PF02862.12 KEG12848.1 - 3.2 7.4 5.6 0.6 9.8 0.8 1.9 2 0 0 2 2 2 0 DDHD domain NOA36 PF06524.7 KEG12848.1 - 6 6.0 8.6 12 5.0 6.0 1.4 1 0 0 1 1 1 0 NOA36 protein WW PF00397.21 KEG12849.1 - 8.1e-10 38.3 0.8 1.5e-09 37.5 0.6 1.5 1 0 0 1 1 1 1 WW domain zf-CCCH PF00642.19 KEG12849.1 - 0.0064 16.1 0.3 0.011 15.4 0.2 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SpoU_methylase PF00588.14 KEG12850.1 - 2.3e-08 34.0 0.2 0.0014 18.5 0.0 4.0 3 1 0 3 3 3 2 SpoU rRNA Methylase family Sigma70_ner PF04546.8 KEG12851.1 - 0.013 15.1 1.1 0.024 14.2 0.5 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region FBPase_3 PF01950.11 KEG12851.1 - 0.027 13.4 0.0 0.042 12.8 0.0 1.1 1 0 0 1 1 1 0 Fructose-1,6-bisphosphatase DUF1619 PF07773.6 KEG12853.1 - 2.7e-60 204.6 0.7 8.1e-59 199.8 1.1 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1619) WD40 PF00400.27 KEG12855.1 - 3.1e-17 61.7 6.8 0.00026 20.7 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat NurA PF09376.5 KEG12856.1 - 0.099 12.1 0.5 0.12 11.8 0.3 1.1 1 0 0 1 1 1 0 NurA domain EF-hand_7 PF13499.1 KEG12857.1 - 6.6e-10 38.9 3.3 1.6e-09 37.7 0.7 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KEG12857.1 - 4.8e-09 34.8 1.9 8.4e-05 21.6 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 KEG12857.1 - 3.1e-08 32.8 0.9 8.3e-05 22.1 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 KEG12857.1 - 4.7e-06 26.1 1.8 4e-05 23.1 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_10 PF14788.1 KEG12857.1 - 0.019 14.6 0.4 0.05 13.2 0.0 1.8 2 0 0 2 2 2 0 EF hand F-box-like PF12937.2 KEG12858.1 - 0.01 15.5 0.2 0.028 14.1 0.1 1.7 1 0 0 1 1 1 0 F-box-like PALP PF00291.20 KEG12860.1 - 9e-59 199.1 2.8 1e-58 198.9 1.9 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF2009 PF09418.5 KEG12861.1 - 4.3e-116 388.4 0.0 1.2e-115 386.9 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2009) LOH1CR12 PF10158.4 KEG12861.1 - 0.027 14.2 0.0 0.063 13.0 0.0 1.6 1 0 0 1 1 1 0 Tumour suppressor protein PSD1 PF07587.6 KEG12862.1 - 0.015 14.7 1.9 0.018 14.4 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1553) DUF3287 PF11690.3 KEG12862.1 - 0.13 12.3 0.1 0.25 11.4 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3287) SRP54 PF00448.17 KEG12863.1 - 2.8e-55 186.8 0.2 6e-55 185.7 0.1 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 KEG12863.1 - 5.4e-14 52.2 6.2 7.2e-14 51.8 0.3 2.1 1 1 1 2 2 2 1 Signal recognition particle, alpha subunit, N-terminal Zeta_toxin PF06414.7 KEG12863.1 - 5.9e-07 28.7 0.0 1.6e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 KEG12863.1 - 6.1e-07 29.6 0.0 2.1e-06 27.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain CbiA PF01656.18 KEG12863.1 - 0.00027 20.4 0.0 0.0026 17.1 0.0 2.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.10 KEG12863.1 - 0.00044 19.9 0.2 0.66 9.6 0.0 2.9 2 1 0 3 3 3 2 NTPase cobW PF02492.14 KEG12863.1 - 0.00052 19.5 0.1 0.0014 18.1 0.1 1.7 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 KEG12863.1 - 0.00054 19.5 0.1 0.0013 18.2 0.0 1.8 1 1 0 1 1 1 1 AAA-like domain AAA_30 PF13604.1 KEG12863.1 - 0.00062 19.3 0.1 0.0015 18.1 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEG12863.1 - 0.00087 19.0 0.3 0.063 13.0 0.0 2.6 1 1 0 2 2 2 1 Part of AAA domain ETF PF01012.16 KEG12863.1 - 0.00092 18.9 0.5 0.061 13.0 0.1 2.6 2 0 0 2 2 2 1 Electron transfer flavoprotein domain SRP54_N PF02881.14 KEG12863.1 - 0.00096 19.2 0.0 0.0021 18.1 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain DAP3 PF10236.4 KEG12863.1 - 0.0013 17.7 0.0 0.0023 16.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 ArsA_ATPase PF02374.10 KEG12863.1 - 0.003 16.6 0.1 0.069 12.1 0.0 2.4 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_33 PF13671.1 KEG12863.1 - 0.0032 17.3 0.0 0.01 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 KEG12863.1 - 0.0071 16.0 0.1 0.1 12.2 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KEG12863.1 - 0.0071 16.2 0.0 0.018 15.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.7 KEG12863.1 - 0.0082 15.8 0.0 0.48 10.0 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KEG12863.1 - 0.0094 15.9 2.4 0.012 15.6 0.0 2.4 3 1 1 4 4 2 1 AAA ATPase domain Metallophos_3 PF14582.1 KEG12863.1 - 0.011 14.8 0.0 0.48 9.5 0.0 2.4 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily ABC_tran PF00005.22 KEG12863.1 - 0.012 15.8 0.0 0.056 13.7 0.0 2.1 2 0 0 2 2 2 0 ABC transporter ArgK PF03308.11 KEG12863.1 - 0.017 13.9 0.1 0.06 12.1 0.0 1.9 1 1 0 1 1 1 0 ArgK protein AAA_24 PF13479.1 KEG12863.1 - 0.022 14.3 0.2 0.2 11.1 0.2 2.4 2 1 0 2 2 2 0 AAA domain APS_kinase PF01583.15 KEG12863.1 - 0.022 14.4 0.0 0.046 13.3 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF2075 PF09848.4 KEG12863.1 - 0.035 13.0 0.0 0.075 11.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF258 PF03193.11 KEG12863.1 - 0.047 12.8 0.0 0.34 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 KEG12863.1 - 0.049 13.5 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 KEG12863.1 - 0.059 12.2 0.0 0.095 11.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 KEG12863.1 - 0.11 12.0 0.0 0.33 10.5 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.15 KEG12863.1 - 0.22 10.1 0.0 0.38 9.3 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit AAA_21 PF13304.1 KEG12863.1 - 0.22 11.4 0.0 0.37 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.16 KEG12863.1 - 0.23 10.7 0.9 1.1 8.4 0.5 2.3 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain SQS_PSY PF00494.14 KEG12865.1 - 1.2e-11 44.3 0.1 2.1e-11 43.6 0.1 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase TPR_11 PF13414.1 KEG12867.1 - 4.5e-11 42.2 6.5 6.9e-10 38.4 1.6 2.8 2 1 1 3 3 3 2 TPR repeat DUF3846 PF12957.2 KEG12867.1 - 1.9e-07 30.7 0.0 1.1e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3846) TPR_1 PF00515.23 KEG12867.1 - 0.00021 20.7 2.4 0.57 9.8 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEG12867.1 - 0.00072 19.2 8.5 0.036 13.9 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 KEG12867.1 - 0.0011 19.0 1.1 0.13 12.4 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEG12867.1 - 0.048 13.9 0.5 0.048 13.9 0.3 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2500 PF10694.4 KEG12867.1 - 0.058 13.4 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) TPR_16 PF13432.1 KEG12867.1 - 0.14 12.8 10.9 0.43 11.3 2.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEG12867.1 - 0.48 11.1 7.4 0.51 11.1 0.4 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat ubiquitin PF00240.18 KEG12868.1 - 3.3e-33 112.8 0.2 4.3e-33 112.5 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 KEG12868.1 - 6.1e-33 112.1 10.5 1e-32 111.5 7.3 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 KEG12868.1 - 3.7e-20 71.4 0.3 5.8e-20 70.7 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KEG12868.1 - 3.8e-05 23.8 0.1 0.00015 21.9 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KEG12868.1 - 0.0014 18.3 0.0 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 KEG12868.1 - 0.0078 16.0 0.1 0.015 15.1 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KEG12868.1 - 0.061 13.5 0.0 0.069 13.3 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Plexin_cytopl PF08337.7 KEG12868.1 - 0.086 11.1 0.3 4.9 5.3 0.1 2.0 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain DUF2870 PF11069.3 KEG12868.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) Hydrolase PF00702.21 KEG12869.1 - 2.6e-13 50.8 0.0 2.3e-08 34.7 0.0 3.3 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEG12869.1 - 2e-10 41.1 0.0 2.3e-09 37.6 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KEG12869.1 - 1.5e-09 37.2 7.2 1.3e-08 34.1 0.0 2.7 3 0 0 3 3 3 2 E1-E2 ATPase Hydrolase_3 PF08282.7 KEG12869.1 - 0.022 14.3 0.1 0.041 13.4 0.1 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEG12869.1 - 0.025 14.5 0.1 0.14 12.0 0.1 2.2 1 1 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Ribosomal_L2_C PF03947.13 KEG12870.1 - 1.4e-17 63.7 0.2 2.3e-17 62.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Sod_Fe_C PF02777.13 KEG12871.1 - 6.4e-39 132.0 0.0 1.2e-38 131.1 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KEG12871.1 - 1.3e-18 67.0 0.1 2.2e-18 66.2 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain zf-Tim10_DDP PF02953.10 KEG12872.1 - 1e-13 50.3 2.7 1.5e-13 49.8 1.8 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 KEG12872.1 - 0.0046 16.4 1.5 0.0054 16.1 1.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) DUF2630 PF10944.3 KEG12872.1 - 0.61 10.2 4.6 1.8 8.7 0.3 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2630) SspB PF04386.8 KEG12873.1 - 0.031 13.8 0.0 1.4 8.4 0.1 2.6 2 0 0 2 2 2 0 Stringent starvation protein B BAR_2 PF10455.4 KEG12873.1 - 0.43 9.4 0.6 1 8.2 0.0 1.9 2 0 0 2 2 2 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Pkinase PF00069.20 KEG12875.1 - 3.9e-29 101.6 0.0 6.8e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG12875.1 - 6.8e-18 64.6 0.0 7.1e-17 61.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG12875.1 - 6.1e-05 22.1 0.0 0.00011 21.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 KEG12876.1 - 4e-20 72.0 0.0 1e-19 70.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG12876.1 - 3.3e-12 46.0 0.0 7.5e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG12876.1 - 0.12 11.2 0.0 0.23 10.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Reticulon PF02453.12 KEG12877.1 - 4.7e-30 104.4 3.0 7.1e-30 103.8 2.1 1.3 1 1 0 1 1 1 1 Reticulon PrgI PF12666.2 KEG12877.1 - 0.0031 17.6 2.4 1.2 9.3 0.1 2.3 2 0 0 2 2 2 2 PrgI family protein DUF2809 PF10990.3 KEG12877.1 - 2 8.8 6.4 2.1 8.7 0.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2809) DUF3927 PF13064.1 KEG12877.1 - 8.6 5.9 8.6 0.72 9.3 1.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3927) DnaJ PF00226.26 KEG12878.1 - 4.5e-08 32.7 0.0 9.1e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Toxin_13 PF07822.6 KEG12878.1 - 0.11 12.4 2.8 0.27 11.1 2.0 1.6 1 0 0 1 1 1 0 Neurotoxin B-IV-like protein Leu_Phe_trans PF03588.9 KEG12879.1 - 4.5e-06 25.9 0.0 6.8e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Leucyl/phenylalanyl-tRNA protein transferase FTHFS PF01268.14 KEG12880.1 - 1.3e-255 848.7 0.0 1.4e-255 848.5 0.0 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase RRM_1 PF00076.17 KEG12882.1 - 3e-11 42.7 0.1 7e-11 41.6 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG12882.1 - 4.1e-10 39.5 0.0 7.2e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG12882.1 - 0.00087 19.0 0.1 0.0014 18.4 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Syntaxin PF00804.20 KEG12882.1 - 0.085 13.0 0.5 0.13 12.4 0.3 1.3 1 0 0 1 1 1 0 Syntaxin Pox_A_type_inc PF04508.7 KEG12882.1 - 0.51 10.2 2.7 1.1 9.2 1.9 1.5 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat AAA PF00004.24 KEG12884.1 - 5.8e-14 52.4 0.0 1e-13 51.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 KEG12884.1 - 2.1e-13 50.0 0.0 4.6e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KEG12884.1 - 4.1e-11 42.8 0.0 7.5e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.1 KEG12884.1 - 7.4e-10 39.1 2.0 6.6e-06 26.2 0.0 3.1 1 1 2 3 3 3 2 AAA ATPase domain Rad17 PF03215.10 KEG12884.1 - 4.6e-09 35.5 0.0 1.7e-05 23.7 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 KEG12884.1 - 7.1e-08 31.7 0.4 2e-07 30.3 0.0 1.9 3 0 0 3 3 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KEG12884.1 - 8.8e-07 29.1 0.0 2.4e-06 27.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEG12884.1 - 5.1e-06 26.1 0.1 1.3e-05 24.7 0.0 1.8 2 0 0 2 2 1 1 Part of AAA domain AAA_11 PF13086.1 KEG12884.1 - 1.2e-05 25.0 0.0 2.7e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 KEG12884.1 - 7.8e-05 22.5 0.0 0.00017 21.4 0.0 1.6 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 KEG12884.1 - 0.00069 18.6 0.0 0.001 18.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.1 KEG12884.1 - 0.00071 19.4 0.0 0.007 16.2 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 KEG12884.1 - 0.00084 19.2 0.0 0.0019 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEG12884.1 - 0.0023 18.7 0.0 0.0067 17.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain DEAD PF00270.24 KEG12884.1 - 0.0027 17.2 0.1 0.47 9.9 0.0 2.3 1 1 0 2 2 2 1 DEAD/DEAH box helicase Mg_chelatase PF01078.16 KEG12884.1 - 0.0028 16.8 0.1 0.0079 15.3 0.1 1.9 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_32 PF13654.1 KEG12884.1 - 0.0044 15.7 0.0 0.042 12.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KEG12884.1 - 0.0068 16.3 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KEG12884.1 - 0.0074 15.8 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KEG12884.1 - 0.016 14.9 0.0 0.052 13.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KEG12884.1 - 0.02 14.3 1.6 0.16 11.3 0.3 2.7 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.8 KEG12884.1 - 0.022 13.6 0.0 0.037 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.13 KEG12884.1 - 0.028 13.8 0.1 0.056 12.9 0.0 1.5 1 1 0 1 1 1 0 FtsK/SpoIIIE family Arch_ATPase PF01637.13 KEG12884.1 - 0.035 13.8 0.0 0.081 12.6 0.0 1.8 1 1 0 1 1 1 0 Archaeal ATPase TrwB_AAD_bind PF10412.4 KEG12884.1 - 0.043 12.4 0.0 0.074 11.6 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.1 KEG12884.1 - 0.055 13.7 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 KEG12884.1 - 0.064 12.7 0.0 0.13 11.8 0.0 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.6 KEG12884.1 - 0.074 12.6 0.1 0.48 10.0 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 KEG12884.1 - 0.13 11.1 0.0 0.24 10.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein NTPase_1 PF03266.10 KEG12884.1 - 0.14 11.8 0.0 0.37 10.4 0.0 1.7 1 0 0 1 1 1 0 NTPase AAA_23 PF13476.1 KEG12884.1 - 0.17 12.1 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain CLASP_N PF12348.3 KEG12885.1 - 0.008 15.5 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 CLASP N terminal LRR_4 PF12799.2 KEG12887.1 - 0.031 13.8 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) ubiquitin PF00240.18 KEG12889.1 - 0.0014 17.9 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family TPR_12 PF13424.1 KEG12890.1 - 1.6e-05 24.7 10.5 0.001 18.9 1.0 3.5 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 KEG12890.1 - 0.013 15.0 6.3 0.024 14.2 0.6 2.8 1 1 2 3 3 3 0 TPR repeat TPR_2 PF07719.12 KEG12890.1 - 0.26 11.2 10.5 2 8.5 0.3 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 KEG12890.1 - 0.6 10.0 3.6 13 5.8 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 KEG12890.1 - 1.3 8.7 4.4 17 5.2 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEG12890.1 - 1.4 9.5 6.7 4.5 7.9 0.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat ATG27 PF09451.5 KEG12891.1 - 1.1e-05 24.8 0.0 1.8e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 27 DUF4307 PF14155.1 KEG12891.1 - 0.02 14.6 3.2 0.34 10.7 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4307) DUF2828 PF11443.3 KEG12892.1 - 0.062 11.5 0.1 0.072 11.2 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) TPT PF03151.11 KEG12894.1 - 5.7e-18 65.0 14.7 5.7e-18 65.0 10.2 2.9 2 1 0 2 2 2 1 Triose-phosphate Transporter family SH3_9 PF14604.1 KEG12895.1 - 2e-09 36.8 0.1 3.5e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KEG12895.1 - 7.1e-09 35.0 0.5 1.4e-08 34.0 0.1 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 KEG12895.1 - 1.4e-07 30.8 0.0 2.5e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_3 PF08239.6 KEG12895.1 - 0.0013 18.8 0.3 0.0027 17.8 0.2 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain Tmemb_cc2 PF10267.4 KEG12895.1 - 0.0053 15.4 0.4 0.0066 15.0 0.3 1.1 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Filament PF00038.16 KEG12895.1 - 0.0079 15.6 2.6 0.0079 15.6 1.8 1.3 1 1 0 1 1 1 1 Intermediate filament protein PEHE PF15275.1 KEG12895.1 - 1.6 9.2 6.4 0.63 10.5 0.4 2.4 2 0 0 2 2 2 0 PEHE domain FliJ PF02050.11 KEG12895.1 - 4.8 7.2 11.2 13 5.8 7.8 1.7 1 1 0 1 1 1 0 Flagellar FliJ protein Nnf1 PF03980.9 KEG12895.1 - 7.1 6.6 8.7 1.6 8.7 0.3 2.5 2 1 1 3 3 3 0 Nnf1 LRR_6 PF13516.1 KEG12896.1 - 4.3e-05 23.1 2.7 3 8.1 0.0 5.0 4 1 1 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.2 KEG12896.1 - 0.00014 21.4 0.1 0.035 13.7 0.0 3.7 2 2 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEG12896.1 - 0.00086 19.0 2.1 1.9 8.8 0.0 4.7 4 1 1 5 5 5 1 Leucine Rich Repeat LRR_9 PF14580.1 KEG12896.1 - 0.13 11.8 1.0 0.36 10.3 0.6 1.9 1 1 0 1 1 1 0 Leucine-rich repeat LRR_8 PF13855.1 KEG12896.1 - 0.59 9.9 4.1 6.7 6.5 0.4 3.7 1 1 2 4 4 4 0 Leucine rich repeat LRR_7 PF13504.1 KEG12896.1 - 1 9.8 3.9 18 6.0 0.0 4.4 4 1 0 4 4 4 0 Leucine rich repeat Phage_lysis PF03245.8 KEG12897.1 - 0.059 13.3 0.3 0.059 13.3 0.2 2.6 3 0 0 3 3 3 0 Bacteriophage Rz lysis protein DUF641 PF04859.7 KEG12897.1 - 3.9 7.2 12.8 0.2 11.4 2.8 2.6 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) CUT PF02376.10 KEG12899.1 - 0.099 12.4 0.1 0.34 10.7 0.0 1.8 2 0 0 2 2 2 0 CUT domain MFS_1 PF07690.11 KEG12900.1 - 2.6e-11 42.8 28.0 2.6e-11 42.8 19.4 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily Nodulin-like PF06813.8 KEG12900.1 - 1.9e-05 24.0 8.0 1.9e-05 24.0 5.5 2.5 3 0 0 3 3 3 1 Nodulin-like GlcNAc_2-epim PF07221.6 KEG12901.1 - 2e-54 184.8 0.3 2.8e-54 184.4 0.2 1.1 1 0 0 1 1 1 1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) PPR PF01535.15 KEG12901.1 - 0.15 12.1 1.1 0.3 11.1 0.0 2.2 2 0 0 2 2 2 0 PPR repeat TPR_11 PF13414.1 KEG12902.1 - 3e-10 39.6 4.1 3e-06 26.7 0.2 3.4 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 KEG12902.1 - 3.1e-05 23.5 0.7 0.27 11.2 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 KEG12902.1 - 0.0019 17.6 0.1 6.3 6.5 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEG12902.1 - 0.062 14.0 0.3 0.062 14.0 0.2 3.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEG12902.1 - 7.2 7.5 15.3 0.18 12.5 0.4 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TP6A_N PF04406.9 KEG12906.1 - 2.5e-08 33.4 0.0 5.5e-08 32.3 0.0 1.5 2 0 0 2 2 2 1 Type IIB DNA topoisomerase DUF2399 PF09664.5 KEG12906.1 - 0.0004 20.2 0.0 0.00064 19.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2399) NDK PF00334.14 KEG12907.1 - 0.065 13.0 0.0 7.8 6.3 0.0 3.5 4 0 0 4 4 4 0 Nucleoside diphosphate kinase NDK PF00334.14 KEG12908.1 - 4.1e-11 42.7 0.0 0.068 12.9 0.0 7.4 7 0 0 7 7 7 5 Nucleoside diphosphate kinase Mito_fiss_reg PF05308.6 KEG12911.1 - 0.13 11.6 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator OB_NTP_bind PF07717.11 KEG12912.1 - 4e-25 87.8 0.0 7.1e-25 87.0 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KEG12912.1 - 1.1e-20 73.5 0.0 2.1e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KEG12912.1 - 1.3e-11 44.2 0.0 2.6e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Gryzun PF07919.7 KEG12913.1 - 1.2e-31 109.7 0.0 1.7e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Trs65 PF12735.2 KEG12913.1 - 0.0046 16.3 0.1 0.2 10.9 0.0 2.4 2 0 0 2 2 2 1 TRAPP trafficking subunit Trs65 Gryzun-like PF12742.2 KEG12913.1 - 0.0079 15.9 0.0 0.02 14.6 0.0 1.7 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking TRAPPC10 PF12584.3 KEG12913.1 - 0.027 13.9 0.0 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 Trafficking protein particle complex subunit 10, TRAPPC10 MMS19_N PF14500.1 KEG12914.1 - 6.9e-24 84.5 0.3 6.9e-24 84.5 0.2 1.9 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II Thymidylate_kin PF02223.12 KEG12915.1 - 5.7e-18 64.9 0.0 9.7e-18 64.1 0.0 1.3 1 0 0 1 1 1 1 Thymidylate kinase PPK2 PF03976.9 KEG12915.1 - 0.013 14.8 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) ArgK PF03308.11 KEG12915.1 - 0.023 13.4 0.0 0.05 12.3 0.0 1.5 2 0 0 2 2 2 0 ArgK protein AfsA PF03756.8 KEG12915.1 - 0.047 13.4 0.0 0.099 12.3 0.0 1.5 1 0 0 1 1 1 0 A-factor biosynthesis hotdog domain Ribosomal_L35Ae PF01247.13 KEG12916.1 - 1.3e-37 127.4 0.9 1.9e-37 126.9 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 KEG12916.1 - 0.0036 17.1 0.2 0.89 9.5 0.0 2.3 2 1 0 2 2 2 2 RimM N-terminal domain DUF4028 PF13220.1 KEG12917.1 - 0.12 12.0 0.0 4.8 6.8 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF4028) Myosin_head PF00063.16 KEG12919.1 - 3.2e-162 541.0 0.0 4.4e-162 540.6 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.1 KEG12919.1 - 0.0056 16.8 0.1 0.033 14.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 KEG12919.1 - 0.037 12.9 0.0 0.11 11.4 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein CDC37_N PF03234.9 KEG12919.1 - 0.09 13.0 1.4 0.22 11.8 0.6 1.9 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding adh_short PF00106.20 KEG12920.1 - 1.9e-15 57.1 0.1 4e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEG12920.1 - 1.9e-05 24.4 0.0 2.7e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 KR domain SRP40_C PF05022.7 KEG12922.1 - 4.3e-06 27.1 1.4 6.7e-06 26.5 1.0 1.3 1 0 0 1 1 1 1 SRP40, C-terminal domain HMG14_17 PF01101.13 KEG12922.1 - 3.2 8.5 9.0 0.14 12.8 0.8 2.5 1 1 2 3 3 2 0 HMG14 and HMG17 WD40 PF00400.27 KEG12923.1 - 5.5e-62 203.5 25.6 7.9e-14 50.9 1.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KEG12923.1 - 0.0074 15.7 0.0 0.97 8.9 0.0 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PSP1 PF04468.7 KEG12924.1 - 3.1e-24 84.7 0.6 6.7e-24 83.6 0.4 1.6 1 0 0 1 1 1 1 PSP1 C-terminal conserved region PAM2 PF07145.10 KEG12924.1 - 0.41 10.2 4.6 0.87 9.2 3.2 1.5 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Dynamitin PF04912.9 KEG12925.1 - 0.054 12.3 2.1 0.054 12.2 0.4 1.7 2 0 0 2 2 2 0 Dynamitin Allatostatin PF05953.7 KEG12925.1 - 0.11 13.0 0.9 29 5.5 0.0 3.9 3 0 0 3 3 3 0 Allatostatin WASH_WAHD PF11945.3 KEG12925.1 - 0.15 11.3 1.6 0.33 10.2 0.1 2.1 2 0 0 2 2 2 0 WAHD domain of WASH complex bZIP_1 PF00170.16 KEG12925.1 - 2.2 8.3 9.0 12 5.9 0.3 3.3 3 0 0 3 3 3 0 bZIP transcription factor Allexi_40kDa PF05549.6 KEG12925.1 - 3 7.0 5.3 18 4.5 0.7 2.3 1 1 1 2 2 2 0 Allexivirus 40kDa protein EMP24_GP25L PF01105.19 KEG12925.1 - 3.2 7.4 6.0 1.8 8.2 0.6 2.5 2 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD GAS PF13851.1 KEG12925.1 - 3.9 6.6 9.9 0.19 10.8 0.5 2.8 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Fmp27_WPPW PF10359.4 KEG12925.1 - 5.7 5.2 6.5 1.9 6.8 1.3 2.0 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain DEAD PF00270.24 KEG12926.1 - 3.4e-43 147.0 0.0 4.6e-39 133.6 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KEG12926.1 - 1.2e-26 92.3 0.1 7.6e-26 89.7 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEG12926.1 - 4.8e-06 26.5 0.0 2.6e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Limkain-b1 PF11608.3 KEG12927.1 - 2.9 7.6 5.6 2.2 8.0 0.2 3.1 3 0 0 3 3 3 0 Limkain b1 Kinesin PF00225.18 KEG12928.1 - 1.1e-81 274.1 9.8 2.5e-50 171.0 0.0 3.4 4 1 0 5 5 5 2 Kinesin motor domain FHA PF00498.21 KEG12929.1 - 1.6e-14 53.7 0.1 3.1e-14 52.8 0.1 1.4 1 0 0 1 1 1 1 FHA domain zf-C3HC4 PF00097.20 KEG12929.1 - 5.2e-07 29.2 11.0 5.2e-07 29.2 7.6 4.3 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEG12929.1 - 4e-06 26.7 12.4 4e-06 26.7 8.6 4.4 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEG12929.1 - 8.7e-06 25.3 9.0 8.7e-06 25.3 6.2 4.2 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEG12929.1 - 2.4e-05 23.9 10.0 2.4e-05 23.9 6.9 4.4 4 1 1 5 5 5 1 zinc-RING finger domain zf-RING_2 PF13639.1 KEG12929.1 - 6.3e-05 22.7 11.4 6.3e-05 22.7 7.9 4.3 3 2 2 5 5 5 1 Ring finger domain zf-RING_6 PF14835.1 KEG12929.1 - 0.00047 19.8 6.6 0.00047 19.8 4.6 2.8 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 KEG12929.1 - 0.001 18.7 8.2 0.0041 16.8 5.7 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 KEG12929.1 - 0.0028 17.7 4.9 0.0028 17.7 3.4 3.4 3 0 0 3 3 3 1 RING-H2 zinc finger NRDE PF05742.7 KEG12930.1 - 6.1e-24 84.7 0.0 1.4e-13 50.7 0.0 3.1 3 0 0 3 3 3 3 NRDE protein DUF4586 PF15239.1 KEG12931.1 - 4.9e-35 121.5 3.0 6.9e-35 121.0 2.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) VTC PF09359.5 KEG12932.1 - 4.1e-77 258.9 0.0 6e-77 258.4 0.0 1.3 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.10 KEG12932.1 - 0.018 15.2 1.1 0.018 15.2 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF202) AAA_2 PF07724.9 KEG12933.1 - 2.4e-42 144.7 0.3 5.6e-34 117.5 0.1 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 KEG12933.1 - 2e-12 47.4 1.4 6.2e-05 23.2 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KEG12933.1 - 1e-06 28.5 0.3 1e-06 28.5 0.2 3.0 3 0 0 3 3 3 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 KEG12933.1 - 1.7e-06 27.8 0.2 1.5e-05 24.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KEG12933.1 - 8.3e-06 25.9 0.0 0.002 18.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KEG12933.1 - 1.8e-05 25.5 0.3 6.8e-05 23.6 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 KEG12933.1 - 5.1e-05 23.5 0.9 0.0002 21.6 0.1 2.5 3 1 0 3 3 2 1 AAA domain AAA_16 PF13191.1 KEG12933.1 - 5.4e-05 23.2 0.0 0.041 13.8 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain MCM PF00493.18 KEG12933.1 - 0.00026 19.8 0.0 0.0071 15.1 0.0 2.3 2 0 0 2 2 2 1 MCM2/3/5 family Zeta_toxin PF06414.7 KEG12933.1 - 0.00047 19.3 0.1 0.0016 17.5 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin Sigma54_activat PF00158.21 KEG12933.1 - 0.0035 16.8 0.0 0.055 12.9 0.0 2.7 2 1 1 3 3 3 1 Sigma-54 interaction domain AAA_33 PF13671.1 KEG12933.1 - 0.0059 16.4 0.0 0.024 14.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KEG12933.1 - 0.0083 16.0 0.1 2.6 7.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KEG12933.1 - 0.014 14.4 0.3 0.61 9.0 0.0 2.7 2 1 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus NTPase_1 PF03266.10 KEG12933.1 - 0.021 14.5 0.4 0.57 9.8 0.0 2.4 2 0 0 2 2 2 0 NTPase Mg_chelatase PF01078.16 KEG12933.1 - 0.021 13.9 0.1 0.11 11.6 0.0 2.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI ATP-synt_ab PF00006.20 KEG12933.1 - 0.026 14.0 0.0 0.054 12.9 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain ResIII PF04851.10 KEG12933.1 - 0.03 14.1 0.2 0.12 12.1 0.0 2.1 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.12 KEG12933.1 - 0.041 13.2 0.0 0.1 11.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.22 KEG12933.1 - 0.047 13.9 0.0 0.79 10.0 0.0 2.4 2 0 0 2 2 2 0 ABC transporter IPT PF01745.11 KEG12933.1 - 0.051 12.7 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Isopentenyl transferase AAA_28 PF13521.1 KEG12933.1 - 0.057 13.3 0.2 0.27 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain CPT PF07931.7 KEG12933.1 - 0.064 12.8 0.0 0.23 11.0 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein MobB PF03205.9 KEG12933.1 - 0.073 12.7 0.1 0.56 9.9 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B UCH PF00443.24 KEG12934.1 - 3e-41 141.3 0.0 6.8e-41 140.1 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEG12934.1 - 2.1e-10 40.5 0.0 1.4e-09 37.8 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MCM PF00493.18 KEG12935.1 - 1.4e-125 418.4 0.0 1.9e-125 418.0 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KEG12935.1 - 8.7e-16 58.5 0.0 1e-14 55.0 0.0 2.4 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.9 KEG12935.1 - 8.9e-11 41.6 0.0 2.1e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KEG12935.1 - 5.9e-08 32.1 0.1 6.2e-06 25.5 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KEG12935.1 - 0.00058 19.4 0.0 0.0014 18.2 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KEG12935.1 - 0.0099 15.3 0.3 0.45 9.9 0.0 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain NTPase_1 PF03266.10 KEG12935.1 - 0.016 14.9 0.2 3.2 7.4 0.1 2.5 1 1 1 2 2 2 0 NTPase Ribosomal_L37e PF01907.14 KEG12935.1 - 0.2 11.4 1.4 1.8 8.4 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein L37e zf-BED PF02892.10 KEG12935.1 - 0.35 10.6 2.3 0.53 10.0 0.4 2.0 2 0 0 2 2 2 0 BED zinc finger DLIC PF05783.6 KEG12936.1 - 5.2e-05 22.1 1.5 6.7e-05 21.7 0.1 1.9 1 1 1 2 2 2 1 Dynein light intermediate chain (DLIC) MFS_1 PF07690.11 KEG12937.1 - 2.5e-33 115.2 34.7 1.2e-16 60.3 11.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 KEG12937.1 - 1.7e-07 30.1 20.4 2.9e-05 22.7 1.9 3.8 2 2 2 4 4 4 3 Vacuole effluxer Atg22 like Sugar_tr PF00083.19 KEG12937.1 - 3.5e-05 22.5 24.5 0.01 14.4 7.1 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 KEG12937.1 - 0.06 11.7 27.1 0.096 11.0 1.6 2.4 2 1 0 2 2 2 0 MFS/sugar transport protein TPR_11 PF13414.1 KEG12938.1 - 0.01 15.4 0.2 0.35 10.5 0.1 2.8 3 0 0 3 3 3 0 TPR repeat TPR_20 PF14561.1 KEG12938.1 - 0.12 12.5 0.1 6.7 6.9 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF937 PF06078.6 KEG12939.1 - 0.026 14.7 5.1 0.044 14.0 0.1 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF937) Kinesin PF00225.18 KEG12940.1 - 4.7e-17 61.7 0.0 6.9e-17 61.1 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain TGT PF01702.13 KEG12941.1 - 2.2e-36 125.3 0.2 3.6e-36 124.6 0.1 1.3 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Myosin_head PF00063.16 KEG12942.1 - 2.1e-163 544.9 0.0 3.8e-163 544.1 0.0 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.22 KEG12942.1 - 0.0028 17.1 0.3 0.0028 17.1 0.2 3.2 3 0 0 3 3 3 1 IQ calmodulin-binding motif AAA_22 PF13401.1 KEG12942.1 - 0.027 14.6 0.0 0.12 12.5 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KEG12942.1 - 0.19 11.6 0.0 0.19 11.6 0.0 2.9 2 1 1 3 3 3 0 AAA ATPase domain SMC_N PF02463.14 KEG12943.1 - 3.1e-59 199.8 16.4 5.7e-59 198.9 11.4 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KEG12943.1 - 3.6e-27 94.7 0.2 2e-26 92.2 0.0 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KEG12943.1 - 2.1e-14 54.1 7.3 3.9e-07 30.3 0.0 3.4 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.1 KEG12943.1 - 1.7e-06 27.4 0.0 3.6e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 KEG12943.1 - 0.0013 19.0 53.8 0.0013 19.0 37.3 5.9 2 2 0 2 2 2 1 AAA domain AAA_13 PF13166.1 KEG12943.1 - 0.093 11.1 0.0 0.093 11.1 0.0 5.5 3 2 2 5 5 5 0 AAA domain ABC_tran PF00005.22 KEG12943.1 - 0.1 12.9 0.0 0.1 12.9 0.0 6.5 3 2 0 3 3 3 0 ABC transporter DUF2721 PF11026.3 KEG12943.1 - 1.3 8.6 6.5 0.83 9.3 0.9 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) Tox-URI2 PF15653.1 KEG12943.1 - 5.7 7.2 13.4 1.5 9.0 0.8 4.2 2 1 0 2 2 2 0 URI fold toxin 2 SET PF00856.23 KEG12945.1 - 9.5e-10 39.0 0.0 2.6e-09 37.5 0.0 1.7 1 1 0 1 1 1 1 SET domain LRR_6 PF13516.1 KEG12946.1 - 3.9e-07 29.4 0.1 0.46 10.6 0.0 5.1 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.28 KEG12946.1 - 0.00013 21.5 0.0 3.8 7.8 0.0 5.3 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_8 PF13855.1 KEG12946.1 - 0.0035 17.0 0.0 0.065 13.0 0.0 3.0 4 0 0 4 4 4 1 Leucine rich repeat LRR_4 PF12799.2 KEG12946.1 - 0.0037 16.8 0.0 1 9.0 0.0 3.7 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 KEG12946.1 - 0.035 14.2 0.5 18 6.1 0.1 4.6 6 0 0 6 6 6 0 Leucine rich repeat CRIC_ras_sig PF10534.4 KEG12946.1 - 0.14 12.2 0.5 0.35 10.9 0.1 1.8 2 0 0 2 2 2 0 Connector enhancer of kinase suppressor of ras DUF694 PF05107.7 KEG12948.1 - 0.047 12.9 0.6 0.074 12.2 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF694) LysM PF01476.15 KEG12949.1 - 1.1e-09 37.9 0.0 0.00045 20.0 0.0 2.6 2 0 0 2 2 2 2 LysM domain eIF2A PF08662.6 KEG12950.1 - 9.7e-43 146.1 0.0 5.1e-33 114.4 0.0 3.2 3 0 0 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 KEG12950.1 - 0.2 11.5 0.7 39 4.3 0.0 4.1 5 0 0 5 5 5 0 WD domain, G-beta repeat DUF1738 PF08401.6 KEG12952.1 - 3.3e-07 30.0 0.0 0.003 17.2 0.0 2.6 2 1 0 3 3 3 2 Domain of unknown function (DUF1738) Macoilin PF09726.4 KEG12955.1 - 1.9 6.6 10.2 2.5 6.2 7.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Peptidase_S28 PF05577.7 KEG12956.1 - 9.4e-49 166.1 0.0 1.3e-48 165.6 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Dpy-30 PF05186.8 KEG12957.1 - 0.00022 20.6 1.0 0.49 9.9 0.0 2.2 2 0 0 2 2 2 2 Dpy-30 motif HEAT PF02985.17 KEG12959.1 - 1.9e-09 36.8 10.6 0.0029 17.5 0.1 7.2 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.1 KEG12959.1 - 4.6e-09 36.4 2.6 0.0015 18.7 0.0 5.9 3 2 2 5 5 5 2 HEAT repeats HEAT_EZ PF13513.1 KEG12959.1 - 9e-08 32.3 8.0 0.0022 18.4 0.1 7.6 7 0 0 7 7 7 1 HEAT-like repeat Adaptin_N PF01602.15 KEG12959.1 - 6.7e-05 21.4 1.0 0.01 14.1 0.0 3.5 3 3 0 3 3 3 1 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 KEG12959.1 - 6.8e-05 23.1 0.8 5.4 7.4 0.0 4.6 3 1 0 3 3 3 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 KEG12959.1 - 0.00013 21.9 0.7 0.11 12.3 0.0 3.4 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 KEG12959.1 - 0.00072 18.9 0.3 4 6.7 0.0 4.7 4 1 0 4 4 4 1 CLASP N terminal MMS19_C PF12460.3 KEG12959.1 - 0.2 10.3 2.4 24 3.5 0.0 3.7 4 0 0 4 4 4 0 RNAPII transcription regulator C-terminal MMS19_C PF12460.3 KEG12960.1 - 0.11 11.1 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal RRM_1 PF00076.17 KEG12961.1 - 4.5e-09 35.8 0.0 8.8e-09 34.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG12961.1 - 3.1e-08 33.4 0.0 1e-07 31.8 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG12961.1 - 2.6e-05 23.9 0.0 7.9e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.1 KEG12961.1 - 0.0001 22.2 0.0 0.00054 19.9 0.0 2.0 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 Nup35_RRM_2 PF14605.1 KEG12961.1 - 0.096 12.4 0.1 0.89 9.3 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DinB_2 PF12867.2 KEG12961.1 - 0.31 11.3 1.7 11 6.4 0.1 2.6 1 1 1 2 2 2 0 DinB superfamily Pheromone PF08015.6 KEG12961.1 - 0.61 10.9 3.0 1.6 9.6 1.1 2.3 2 0 0 2 2 2 0 Fungal mating-type pheromone FYVE PF01363.16 KEG12963.1 - 0.082 12.8 1.4 0.25 11.2 1.0 1.9 1 1 0 1 1 1 0 FYVE zinc finger PI3_PI4_kinase PF00454.22 KEG12964.1 - 7e-16 58.4 0.1 1.8e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase BAF1_ABF1 PF04684.8 KEG12964.1 - 2.2e-05 23.5 16.9 2.2e-05 23.5 11.7 2.0 2 0 0 2 2 2 1 BAF1 / ABF1 chromatin reorganising factor Zip PF02535.17 KEG12964.1 - 0.003 16.6 2.9 0.0041 16.1 2.0 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Neur_chan_memb PF02932.11 KEG12964.1 - 0.3 10.9 2.1 0.54 10.1 1.4 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Innate_immun PF12782.2 KEG12964.1 - 0.49 9.5 13.0 0.81 8.8 9.0 1.2 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family BRF1 PF07741.8 KEG12964.1 - 7 6.9 9.9 2.4 8.4 4.1 2.0 2 0 0 2 2 2 0 Brf1-like TBP-binding domain ATG16 PF08614.6 KEG12966.1 - 0.033 14.0 28.8 0.36 10.6 15.9 2.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DivIC PF04977.10 KEG12966.1 - 0.07 12.6 0.1 0.07 12.6 0.1 3.9 2 1 2 4 4 4 0 Septum formation initiator NPV_P10 PF05531.7 KEG12966.1 - 0.12 12.6 9.4 0.99 9.6 2.3 3.0 3 0 0 3 3 2 0 Nucleopolyhedrovirus P10 protein AAA_33 PF13671.1 KEG12966.1 - 0.32 10.8 8.8 1.2 8.9 4.4 2.5 2 0 0 2 2 2 0 AAA domain CDC37_N PF03234.9 KEG12966.1 - 0.45 10.8 13.7 0.44 10.8 8.4 1.8 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding AAA_23 PF13476.1 KEG12966.1 - 0.52 10.6 8.8 1 9.6 6.1 1.4 1 0 0 1 1 1 0 AAA domain Syntaxin-6_N PF09177.6 KEG12966.1 - 0.64 10.4 16.2 17 5.8 8.2 3.8 3 1 1 4 4 4 0 Syntaxin 6, N-terminal GAS PF13851.1 KEG12966.1 - 0.78 8.9 24.1 0.011 14.9 7.5 3.1 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF87 PF01935.12 KEG12966.1 - 0.99 9.1 5.4 1.7 8.4 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF87 EMP24_GP25L PF01105.19 KEG12966.1 - 1.1 8.9 4.3 3 7.5 3.0 1.7 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Macoilin PF09726.4 KEG12966.1 - 1.1 7.4 11.8 0.14 10.3 5.1 1.8 2 0 0 2 2 2 0 Transmembrane protein Reo_sigmaC PF04582.7 KEG12966.1 - 1.3 8.1 4.7 4 6.5 2.4 2.4 2 1 0 2 2 2 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 KEG12966.1 - 1.4 7.3 11.3 2.3 6.5 7.9 1.2 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 KEG12966.1 - 3.9 5.2 10.8 6.8 4.4 7.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Phage_GP20 PF06810.6 KEG12966.1 - 5.3 6.4 24.8 0.072 12.5 8.2 2.5 2 1 1 3 3 3 0 Phage minor structural protein GP20 Tropomyosin_1 PF12718.2 KEG12966.1 - 6.6 6.5 30.3 12 5.7 16.9 2.8 2 1 0 2 2 2 0 Tropomyosin like DivIVA PF05103.8 KEG12966.1 - 8.8 6.3 25.1 59 3.7 0.0 4.0 3 1 1 4 4 4 0 DivIVA protein DUF2353 PF09789.4 KEG12966.1 - 9.6 5.3 29.1 2.6 7.2 2.7 2.9 2 1 1 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) Prominin PF05478.6 KEG12966.1 - 9.6 3.5 9.2 20 2.5 6.4 1.5 1 0 0 1 1 1 0 Prominin SRR1 PF07985.7 KEG12967.1 - 0.00033 20.5 0.0 0.039 13.9 0.0 2.4 2 0 0 2 2 2 2 SRR1 Methyltransf_26 PF13659.1 KEG12968.1 - 1.6e-13 50.6 0.0 2.6e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEG12968.1 - 0.00039 19.8 0.0 0.21 10.9 0.0 2.9 1 1 1 2 2 2 2 Methyltransferase small domain Methyltransf_23 PF13489.1 KEG12968.1 - 0.0016 18.2 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEG12968.1 - 0.0042 17.4 0.0 0.0095 16.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEG12968.1 - 0.011 16.2 0.1 0.19 12.3 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 KEG12968.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 dCMP_cyt_deam_1 PF00383.17 KEG12969.1 - 8.1e-06 25.4 1.1 2e-05 24.1 0.8 1.8 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region NIF3 PF01784.13 KEG12969.1 - 0.17 11.4 0.1 16 4.9 0.0 2.2 1 1 1 2 2 2 0 NIF3 (NGG1p interacting factor 3) DUF3624 PF12292.3 KEG12970.1 - 0.1 13.0 0.1 0.22 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3624) DSPc PF00782.15 KEG12971.1 - 3e-06 26.8 0.1 5.7e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF3079 PF11278.3 KEG12972.1 - 0.052 13.0 1.6 0.33 10.5 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3079) Pkinase PF00069.20 KEG12975.1 - 4e-49 167.1 0.0 7.4e-49 166.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG12975.1 - 2.2e-30 105.6 0.0 4.2e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG12975.1 - 2.4e-07 30.0 0.0 4.6e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like HEAT_EZ PF13513.1 KEG12976.1 - 2.4e-05 24.6 8.7 0.02 15.3 0.0 7.0 7 1 0 7 7 7 1 HEAT-like repeat HEAT PF02985.17 KEG12976.1 - 9.8e-05 22.1 4.9 2.4 8.4 0.0 7.1 7 0 0 7 7 7 1 HEAT repeat IBN_N PF03810.14 KEG12976.1 - 0.00021 21.1 0.2 0.013 15.3 0.1 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain DUF1546 PF07571.8 KEG12976.1 - 0.0013 18.7 0.0 7 6.8 0.0 4.2 4 1 0 4 4 4 1 Protein of unknown function (DUF1546) Cnd1 PF12717.2 KEG12976.1 - 0.0045 16.8 0.2 13 5.6 0.0 4.2 3 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 UME PF08064.8 KEG12976.1 - 0.054 13.4 0.2 0.65 9.9 0.0 2.9 3 0 0 3 3 3 0 UME (NUC010) domain Vac14_Fab1_bd PF12755.2 KEG12976.1 - 0.1 12.9 0.1 8.6 6.8 0.0 4.0 3 1 0 4 4 4 0 Vacuolar 14 Fab1-binding region SNARE PF05739.14 KEG12977.1 - 2.5e-06 27.0 0.3 7.2e-06 25.6 0.2 1.8 1 0 0 1 1 1 1 SNARE domain Vps51 PF08700.6 KEG12977.1 - 0.066 13.0 0.1 0.18 11.6 0.1 1.8 1 0 0 1 1 1 0 Vps51/Vps67 CAF1 PF04857.15 KEG12978.1 - 9.9e-37 126.6 0.0 4e-24 85.3 0.0 2.0 2 0 0 2 2 2 2 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.15 KEG12978.1 - 0.098 12.1 0.0 11 5.4 0.0 2.7 2 0 0 2 2 2 0 3'-5' exonuclease Peptidase_M24 PF00557.19 KEG12979.1 - 9.1e-50 169.1 0.0 1.7e-49 168.2 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KEG12979.1 - 2.8e-31 107.6 0.0 5.2e-31 106.7 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF1764 PF08576.5 KEG12980.1 - 4.3e-15 56.3 10.5 1.1e-13 51.7 2.5 2.1 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF1764) TSP9 PF11493.3 KEG12980.1 - 0.0012 19.3 0.9 0.0029 18.1 0.6 1.6 1 0 0 1 1 1 1 Thylakoid soluble phosphoprotein TSP9 Gar1 PF04410.9 KEG12980.1 - 0.61 9.5 5.4 1.2 8.5 0.1 2.2 1 1 1 2 2 2 0 Gar1/Naf1 RNA binding region Secretin_N_2 PF07655.8 KEG12980.1 - 4.6 7.7 11.9 8.4 6.8 8.2 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain SET PF00856.23 KEG12981.1 - 2.5e-08 34.4 0.0 1.4e-05 25.4 0.0 3.4 3 1 0 3 3 3 1 SET domain zf-RanBP PF00641.13 KEG12981.1 - 0.099 11.7 2.4 0.83 8.8 0.1 2.4 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Spt4 PF06093.8 KEG12983.1 - 3.2e-12 46.1 0.0 5e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Sigma70_ner PF04546.8 KEG12983.1 - 0.34 10.4 6.6 0.42 10.1 4.6 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Upf2 PF04050.9 KEG12983.1 - 0.52 10.0 9.0 0.7 9.6 6.3 1.1 1 0 0 1 1 1 0 Up-frameshift suppressor 2 HSP90 PF00183.13 KEG12983.1 - 1.5 7.1 4.8 1.8 6.8 3.3 1.0 1 0 0 1 1 1 0 Hsp90 protein Daxx PF03344.10 KEG12983.1 - 1.8 6.9 7.8 2.1 6.7 5.4 1.0 1 0 0 1 1 1 0 Daxx Family TRAP_alpha PF03896.11 KEG12983.1 - 6.3 5.6 7.2 7.8 5.3 5.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2457 PF10446.4 KEG12983.1 - 6.4 5.3 16.6 8.1 5.0 11.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 KEG12983.1 - 9.8 4.0 7.1 12 3.7 5.0 1.0 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.27 KEG12985.1 - 1.2e-12 47.1 9.3 2.3e-06 27.2 0.3 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat IKI3 PF04762.7 KEG12985.1 - 0.38 8.4 0.0 0.62 7.7 0.0 1.2 1 0 0 1 1 1 0 IKI3 family Cpn60_TCP1 PF00118.19 KEG12986.1 - 2.2e-143 478.4 0.8 2.5e-143 478.2 0.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AP_endonuc_2 PF01261.19 KEG12986.1 - 0.039 13.2 0.0 0.21 10.8 0.0 2.0 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Resolvase PF00239.16 KEG12986.1 - 0.08 12.8 1.5 0.18 11.6 0.1 2.3 2 0 0 2 2 2 0 Resolvase, N terminal domain Y_phosphatase2 PF03162.8 KEG12987.1 - 2e-22 79.3 0.0 9.8e-22 77.0 0.0 1.9 1 1 0 1 1 1 1 Tyrosine phosphatase family AUX_IAA PF02309.11 KEG12987.1 - 0.075 12.7 0.2 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 AUX/IAA family Pkinase PF00069.20 KEG12988.1 - 4.7e-35 120.9 0.2 9.4e-30 103.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEG12988.1 - 3.7e-18 65.5 0.2 6.9e-18 64.6 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEG12988.1 - 0.0024 17.6 0.0 0.0048 16.6 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Maf PF02545.9 KEG12989.1 - 2.2e-19 69.3 0.0 2.4e-19 69.2 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein LigB PF02900.13 KEG12989.1 - 0.1 11.5 0.0 0.2 10.6 0.0 1.4 2 0 0 2 2 2 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase Reo_sigmaC PF04582.7 KEG12990.1 - 0.2 10.8 5.9 1.3 8.1 0.2 3.0 3 0 0 3 3 3 0 Reovirus sigma C capsid protein DUF1539 PF07560.6 KEG12990.1 - 0.3 10.9 4.6 0.34 10.7 1.3 2.5 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1539) ERM PF00769.14 KEG12990.1 - 5.5 6.4 45.5 0.064 12.7 9.5 3.3 1 1 2 3 3 3 0 Ezrin/radixin/moesin family Phage_lysozyme PF00959.14 KEG12990.1 - 8.4 6.7 7.2 1.7 8.9 0.1 3.4 3 2 2 5 5 5 0 Phage lysozyme Metallophos_2 PF12850.2 KEG12991.1 - 2.7e-19 69.5 0.1 3.2e-19 69.3 0.1 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain WD40 PF00400.27 KEG12992.1 - 5.8e-12 45.0 8.6 0.00017 21.3 0.0 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KEG12992.1 - 0.044 12.5 0.0 4.4 5.9 0.0 2.2 2 0 0 2 2 2 0 Nup133 N terminal like PAPA-1 PF04795.7 KEG12992.1 - 0.056 14.1 1.1 10 6.8 0.0 2.5 2 0 0 2 2 2 0 PAPA-1-like conserved region LSM PF01423.17 KEG12993.1 - 7.7e-16 57.3 0.0 8.9e-16 57.1 0.0 1.0 1 0 0 1 1 1 1 LSM domain HECT PF00632.20 KEG12995.1 - 1.2e-74 251.3 0.0 2.5e-74 250.2 0.0 1.6 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) ZZ PF00569.12 KEG12995.1 - 0.043 13.3 9.7 0.093 12.2 6.7 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type CIAPIN1 PF05093.8 KEG12995.1 - 0.57 10.2 6.8 0.17 12.0 2.2 2.0 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis CRM1_C PF08767.6 KEG12996.1 - 8.8e-60 202.2 4.7 4.6e-59 199.9 0.0 3.3 4 0 0 4 4 4 1 CRM1 C terminal Xpo1 PF08389.7 KEG12996.1 - 5.3e-28 97.7 6.6 1.3e-27 96.5 0.7 4.0 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 KEG12996.1 - 1.7e-08 34.2 0.1 8.5e-08 32.0 0.0 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain TetR_C_8 PF14278.1 KEG12996.1 - 0.11 12.9 2.3 1.6 9.1 0.0 3.9 4 0 0 4 4 4 0 Transcriptional regulator C-terminal region Mito_carr PF00153.22 KEG12997.1 - 5.5e-46 154.2 0.5 9.7e-16 57.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.22 KEG12998.1 - 5e-54 179.9 1.8 2.8e-18 65.4 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Yip1 PF04893.12 KEG12998.1 - 0.023 14.2 0.5 0.032 13.7 0.3 1.3 1 0 0 1 1 1 0 Yip1 domain zf-BED PF02892.10 KEG12999.1 - 0.14 11.9 5.6 0.21 11.3 3.9 1.4 1 0 0 1 1 1 0 BED zinc finger Kinesin PF00225.18 KEG13000.1 - 4.6e-61 206.3 0.0 7.3e-61 205.7 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain AAA_16 PF13191.1 KEG13000.1 - 0.00065 19.7 0.0 0.0017 18.3 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KEG13000.1 - 0.011 15.8 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KEG13000.1 - 0.074 12.6 0.1 0.97 8.9 0.1 2.2 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 KEG13000.1 - 0.08 11.8 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF87 PF01935.12 KEG13000.1 - 0.13 12.0 0.1 0.35 10.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF87 HSP70 PF00012.15 KEG13001.1 - 1.3e-69 234.7 0.2 1.8e-69 234.2 0.1 1.2 1 0 0 1 1 1 1 Hsp70 protein DUF4582 PF15189.1 KEG13001.1 - 0.0056 15.9 0.7 0.066 12.4 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4582) MreB_Mbl PF06723.8 KEG13001.1 - 0.02 13.4 0.0 0.048 12.2 0.0 1.6 1 0 0 1 1 1 0 MreB/Mbl protein IMS_C PF11799.3 KEG13001.1 - 0.04 13.8 0.2 0.56 10.1 0.0 2.7 3 0 0 3 3 3 0 impB/mucB/samB family C-terminal domain FGGY_C PF02782.11 KEG13001.1 - 0.047 13.3 0.0 0.099 12.2 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain GCV_H PF01597.14 KEG13002.1 - 3.2e-38 130.1 0.5 3.7e-38 129.9 0.4 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 KEG13002.1 - 1.2e-06 27.9 2.5 2.4e-06 27.0 1.2 1.8 1 1 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.1 KEG13002.1 - 0.00054 19.6 0.8 0.00092 18.8 0.4 1.4 1 1 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Fe-ADH PF00465.14 KEG13003.1 - 0.012 14.2 1.9 0.018 13.7 1.3 1.2 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase Lipocalin_2 PF08212.7 KEG13003.1 - 0.1 12.3 0.8 0.4 10.4 0.1 2.1 1 1 1 2 2 2 0 Lipocalin-like domain ArdA PF07275.6 KEG13003.1 - 0.15 12.2 5.1 0.16 12.1 3.0 1.4 1 1 0 1 1 1 0 Antirestriction protein (ArdA) FBP PF07299.6 KEG13003.1 - 0.16 11.2 5.1 0.088 12.1 1.9 1.6 1 1 0 1 1 1 0 Fibronectin-binding protein (FBP) DASH_Dam1 PF08653.5 KEG13003.1 - 0.65 9.8 3.0 3.2 7.5 0.4 2.4 2 0 0 2 2 2 0 DASH complex subunit Dam1 DUF948 PF06103.6 KEG13003.1 - 0.73 9.7 4.1 2 8.3 2.1 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF3552 PF12072.3 KEG13003.1 - 0.94 8.6 34.8 2.6 7.2 4.1 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF3552) Spc7 PF08317.6 KEG13003.1 - 1.2 7.7 25.5 0.029 13.0 8.5 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein APG6 PF04111.7 KEG13003.1 - 1.2 8.0 28.4 0.066 12.2 12.6 2.1 1 1 2 3 3 3 0 Autophagy protein Apg6 AAA_23 PF13476.1 KEG13003.1 - 1.7 8.9 14.4 2.5 8.3 10.0 1.3 1 0 0 1 1 1 0 AAA domain FemAB PF02388.11 KEG13003.1 - 7.7 5.0 12.9 0.37 9.4 4.1 1.9 1 1 0 2 2 2 0 FemAB family DUF4226 PF10774.4 KEG13003.1 - 8 6.5 11.1 4.3 7.4 1.4 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4226) RCC1 PF00415.13 KEG13004.1 - 0.053 13.7 0.2 0.12 12.5 0.1 1.7 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KEG13004.1 - 0.14 11.7 0.5 0.31 10.7 0.3 1.6 1 0 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat Gp_dh_N PF00044.19 KEG13005.1 - 1.3e-27 96.6 0.1 1.9e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Gp_dh_C PF02800.15 KEG13005.1 - 2e-24 85.8 0.0 2.7e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain TrbC PF04956.8 KEG13006.1 - 0.24 11.4 5.2 0.49 10.4 3.6 1.6 1 0 0 1 1 1 0 TrbC/VIRB2 family DUF1761 PF08570.5 KEG13006.1 - 0.38 10.7 5.7 0.8 9.7 4.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1761) Pro_isomerase PF00160.16 KEG13007.1 - 2e-44 151.5 0.1 3.2e-44 150.8 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 KEG13007.1 - 5e-13 48.5 10.9 9.5e-09 34.7 3.0 2.6 2 1 1 3 3 2 2 TPR repeat TPR_2 PF07719.12 KEG13007.1 - 1e-11 43.8 3.1 0.001 18.8 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KEG13007.1 - 5.1e-09 35.3 2.4 0.0021 17.6 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEG13007.1 - 0.00048 20.7 2.6 0.00048 20.7 1.8 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KEG13007.1 - 0.00059 19.7 3.7 0.00075 19.3 1.1 2.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEG13007.1 - 0.014 15.9 7.0 0.025 15.2 1.1 3.3 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 KEG13007.1 - 0.015 15.4 1.2 0.57 10.5 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 KEG13007.1 - 0.049 13.5 1.4 0.71 9.8 0.6 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 KEG13007.1 - 0.091 12.9 3.6 0.27 11.3 1.2 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 KEG13007.1 - 0.096 12.5 0.7 15 5.6 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 KEG13007.1 - 0.11 12.3 2.0 0.4 10.5 1.4 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat Beta_protein PF14350.1 KEG13007.1 - 0.11 11.6 0.1 0.19 10.8 0.1 1.3 2 0 0 2 2 2 0 Beta protein Fis1_TPR_C PF14853.1 KEG13007.1 - 0.16 11.8 0.8 1.1 9.1 0.1 2.4 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 KEG13007.1 - 0.33 11.5 8.6 11 6.7 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat SCAMP PF04144.8 KEG13009.1 - 3.7e-50 170.2 6.8 4.4e-50 170.0 4.7 1.0 1 0 0 1 1 1 1 SCAMP family DUF1129 PF06570.6 KEG13009.1 - 0.00091 18.5 0.1 0.00091 18.5 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1129) A_deaminase PF00962.17 KEG13010.1 - 5.8e-109 363.9 0.0 1.8e-79 267.0 0.0 2.8 3 0 0 3 3 3 2 Adenosine/AMP deaminase PSP PF04046.11 KEG13011.1 - 0.11 11.8 1.6 0.19 11.1 0.3 1.9 2 0 0 2 2 2 0 PSP PRKCSH PF07915.8 KEG13012.1 - 2.1e-09 38.0 0.3 3.6e-09 37.3 0.2 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 KEG13012.1 - 1e-06 28.2 0.0 1.7e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein His_Phos_1 PF00300.17 KEG13013.1 - 3.7e-12 46.6 0.0 6.7e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF2267 PF10025.4 KEG13014.1 - 0.036 14.1 0.1 0.15 12.1 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) Proteasome PF00227.21 KEG13016.1 - 4e-36 124.0 0.0 5.3e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KEG13016.1 - 6.1e-12 44.6 0.2 1.3e-11 43.5 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Porin_3 PF01459.17 KEG13017.1 - 0.087 12.1 0.5 0.11 11.7 0.3 1.3 1 0 0 1 1 1 0 Eukaryotic porin FliJ PF02050.11 KEG13018.1 - 6.2e-05 23.0 20.2 6.2e-05 23.0 14.0 6.2 1 1 5 6 6 6 2 Flagellar FliJ protein Reo_sigmaC PF04582.7 KEG13018.1 - 0.0048 16.1 2.7 0.0048 16.1 1.9 4.0 1 1 4 5 5 5 2 Reovirus sigma C capsid protein PKK PF12474.3 KEG13018.1 - 0.013 15.2 13.5 0.013 15.2 9.3 5.8 1 1 4 5 5 5 0 Polo kinase kinase Filament PF00038.16 KEG13018.1 - 0.013 14.9 84.6 0.12 11.7 32.6 3.0 1 1 1 2 2 2 0 Intermediate filament protein Tup_N PF08581.5 KEG13018.1 - 0.014 15.5 8.0 0.014 15.5 5.5 7.0 2 2 4 7 7 7 0 Tup N-terminal DUF3584 PF12128.3 KEG13018.1 - 2 5.6 93.2 0.14 9.4 33.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF812 PF05667.6 KEG13018.1 - 3.4 6.0 80.5 0.0097 14.4 20.9 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF812) Macoilin PF09726.4 KEG13022.1 - 2.4 6.3 18.4 3.5 5.7 12.8 1.3 1 0 0 1 1 1 0 Transmembrane protein zf-C4pol PF14260.1 KEG13022.1 - 2.8 7.9 8.2 2.4 8.2 3.0 2.6 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta DUF1664 PF07889.7 KEG13022.1 - 7.8 6.3 7.0 1.3 8.8 1.6 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Chorein_N PF12624.2 KEG13024.1 - 6.5e-31 106.3 2.1 3e-30 104.1 0.1 3.0 3 0 0 3 3 3 1 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF1162 PF06650.7 KEG13024.1 - 3.5e-26 92.0 0.0 1e-25 90.4 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1162) DUF3040 PF11239.3 KEG13024.1 - 0.028 14.4 0.7 0.26 11.3 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) EAP30 PF04157.11 KEG13025.1 - 4.2e-75 251.7 0.0 5e-75 251.4 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family 2-Hacid_dh_C PF02826.14 KEG13026.1 - 5.8e-47 159.1 0.0 7.7e-47 158.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 KEG13026.1 - 0.00019 21.3 0.0 0.00031 20.6 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 KEG13026.1 - 0.0013 18.0 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_10 PF13460.1 KEG13026.1 - 0.0018 18.2 0.0 0.0027 17.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 KEG13026.1 - 0.0022 17.9 0.0 0.0043 17.0 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.12 KEG13026.1 - 0.0062 16.9 0.0 0.016 15.6 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.16 KEG13026.1 - 0.16 11.7 0.1 0.36 10.6 0.0 1.5 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF4315 PF14193.1 KEG13027.1 - 0.12 12.3 13.0 0.48 10.3 3.0 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4315) Methyltransf_PK PF05891.7 KEG13028.1 - 1e-62 211.3 0.0 1.2e-62 211.0 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_11 PF08241.7 KEG13028.1 - 2.3e-10 40.8 0.0 4.4e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEG13028.1 - 1.4e-07 32.0 0.0 2.4e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEG13028.1 - 2.1e-06 27.3 0.0 4.5e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEG13028.1 - 2.8e-06 27.7 0.0 4.8e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEG13028.1 - 8.4e-06 25.5 0.0 1.3e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 KEG13028.1 - 1.2e-05 24.6 0.0 1.4e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_25 PF13649.1 KEG13028.1 - 0.0013 19.1 0.0 0.0026 18.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 KEG13028.1 - 0.0027 17.1 0.0 0.0038 16.6 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.9 KEG13028.1 - 0.0029 17.0 0.0 0.0058 16.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KEG13028.1 - 0.029 14.3 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Tetraspannin PF00335.15 KEG13029.1 - 0.00012 21.4 4.8 0.00014 21.1 3.3 1.1 1 0 0 1 1 1 1 Tetraspanin family Pox_I5 PF04713.7 KEG13029.1 - 0.026 14.2 1.8 0.026 14.2 1.2 2.1 1 1 1 2 2 2 0 Poxvirus protein I5 DUF2207 PF09972.4 KEG13029.1 - 0.32 9.5 1.6 0.35 9.3 1.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2269 PF10027.4 KEG13029.1 - 8.4 6.1 11.8 11 5.7 8.2 1.3 1 1 0 1 1 1 0 Predicted integral membrane protein (DUF2269) PilX_N PF14341.1 KEG13030.1 - 1.3 8.7 7.3 0.15 11.7 1.1 2.1 2 0 0 2 2 2 0 PilX N-terminal Pkinase PF00069.20 KEG13031.1 - 1.7e-69 233.8 0.0 3.2e-69 232.9 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG13031.1 - 4.3e-29 101.3 0.0 5.9e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 KEG13031.1 - 1.6e-08 34.6 0.0 4.1e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 KEG13031.1 - 0.00027 19.9 0.0 0.002 17.1 0.0 2.3 2 1 0 2 2 2 1 Kinase-like Pkinase_C PF00433.19 KEG13031.1 - 0.018 15.5 1.2 0.018 15.5 0.8 1.8 2 0 0 2 2 2 0 Protein kinase C terminal domain PH_11 PF15413.1 KEG13031.1 - 0.13 12.5 3.8 2 8.6 2.7 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain DUF1754 PF08555.5 KEG13032.1 - 0.0042 17.6 2.8 0.15 12.7 2.6 2.2 1 1 1 2 2 2 2 Eukaryotic family of unknown function (DUF1754) DUF1796 PF08795.5 KEG13032.1 - 0.15 11.6 11.9 1.7 8.2 1.7 2.4 2 0 0 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) CPSF73-100_C PF11718.3 KEG13032.1 - 0.17 11.1 16.5 0.55 9.5 1.9 2.2 2 0 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term DUF912 PF06024.7 KEG13032.1 - 0.39 10.7 9.0 3 7.9 1.0 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Hid1 PF12722.2 KEG13032.1 - 1.1 6.8 3.4 1.4 6.5 2.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ERF PF04404.7 KEG13032.1 - 3.9 6.9 9.8 8.5 5.8 1.1 2.2 2 0 0 2 2 2 0 ERF superfamily PDGF_N PF04692.8 KEG13032.1 - 7.4 7.1 25.3 16 6.0 6.7 2.8 1 1 1 2 2 2 0 Platelet-derived growth factor, N terminal region MgtE_N PF03448.12 KEG13033.1 - 0.019 15.2 0.5 0.87 9.9 0.0 3.0 2 0 0 2 2 2 0 MgtE intracellular N domain Stork_head PF10264.4 KEG13033.1 - 0.2 11.8 1.9 0.57 10.3 1.3 1.8 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain AAA_4 PF04326.9 KEG13035.1 - 0.05 13.7 0.0 0.11 12.7 0.0 1.5 1 1 0 1 1 1 0 Divergent AAA domain Arm PF00514.18 KEG13036.1 - 3e-23 80.7 18.5 0.02 14.6 0.0 12.9 13 0 0 13 13 13 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KEG13036.1 - 4.7e-12 46.0 8.1 0.013 15.7 0.2 7.3 2 2 3 6 6 6 3 HEAT repeats Atx10homo_assoc PF09759.4 KEG13036.1 - 4.5e-09 35.9 16.4 0.39 10.4 0.1 8.0 3 3 6 9 9 9 6 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.1 KEG13036.1 - 8.4e-05 22.9 8.6 0.14 12.7 0.1 6.7 7 2 1 8 8 8 1 HEAT-like repeat Lactamase_B PF00753.22 KEG13037.1 - 1.7e-09 37.6 0.3 1.5e-08 34.4 0.2 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KEG13037.1 - 0.016 14.7 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain DJ-1_PfpI PF01965.19 KEG13038.1 - 2.4e-26 91.9 0.4 3e-26 91.6 0.3 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 KEG13038.1 - 2e-08 33.6 0.2 2.5e-08 33.3 0.1 1.1 1 0 0 1 1 1 1 Putative amidotransferase Toxin_28 PF08115.6 KEG13038.1 - 0.14 11.7 0.2 0.46 10.1 0.1 1.9 1 0 0 1 1 1 0 SFI toxin family Phage_GP20 PF06810.6 KEG13040.1 - 0.0042 16.5 4.7 0.0042 16.5 3.2 3.9 4 0 0 4 4 4 2 Phage minor structural protein GP20 MscS_porin PF12795.2 KEG13040.1 - 0.05 12.9 9.2 0.014 14.7 3.7 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain GAS PF13851.1 KEG13040.1 - 0.068 12.3 39.5 0.075 12.2 4.5 4.6 2 2 1 4 4 4 0 Growth-arrest specific micro-tubule binding PilJ PF13675.1 KEG13040.1 - 0.55 10.5 11.8 16 5.8 0.4 4.4 2 2 2 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term Reo_sigmaC PF04582.7 KEG13040.1 - 0.97 8.5 6.6 0.33 10.0 1.2 2.5 2 1 1 3 3 3 0 Reovirus sigma C capsid protein APG6 PF04111.7 KEG13040.1 - 1.3 7.9 34.9 0.021 13.8 9.7 2.7 2 1 1 3 3 3 0 Autophagy protein Apg6 Med9 PF07544.8 KEG13040.1 - 1.6 8.4 10.5 4.3 7.1 1.6 4.0 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Fib_alpha PF08702.5 KEG13040.1 - 3.9 7.6 23.8 2.2 8.4 0.2 4.1 2 2 2 4 4 4 0 Fibrinogen alpha/beta chain family FlxA PF14282.1 KEG13040.1 - 9.8 6.1 12.8 1.6 8.6 2.4 3.3 2 1 2 4 4 4 0 FlxA-like protein Kinesin PF00225.18 KEG13042.1 - 2e-81 273.3 0.0 2e-81 273.3 0.0 2.1 3 0 0 3 3 3 1 Kinesin motor domain MMR_HSR1 PF01926.18 KEG13042.1 - 0.007 16.3 0.0 0.16 11.8 0.0 3.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KEG13042.1 - 0.026 15.0 0.0 9.4 6.7 0.0 4.0 3 0 0 3 3 3 0 Miro-like protein AAA_17 PF13207.1 KEG13042.1 - 0.036 14.8 0.8 4.1 8.2 0.0 4.0 4 0 0 4 4 4 0 AAA domain AAA_22 PF13401.1 KEG13042.1 - 0.07 13.2 0.7 1.6 8.8 0.0 3.3 4 0 0 4 4 4 0 AAA domain GrpE PF01025.14 KEG13043.1 - 1.6e-38 131.8 1.8 2e-38 131.5 1.2 1.2 1 0 0 1 1 1 1 GrpE Met_gamma_lyase PF06838.6 KEG13043.1 - 0.018 13.3 0.1 0.024 12.9 0.1 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase SPX PF03105.14 KEG13043.1 - 0.038 13.7 0.5 0.049 13.4 0.4 1.2 1 0 0 1 1 1 0 SPX domain ATP-synt_B PF00430.13 KEG13043.1 - 0.064 13.0 3.9 0.099 12.4 2.7 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Laminin_II PF06009.7 KEG13043.1 - 0.065 12.9 0.6 0.13 11.9 0.4 1.5 1 0 0 1 1 1 0 Laminin Domain II Pox_A_type_inc PF04508.7 KEG13043.1 - 5.8 6.9 7.9 1.4 8.8 2.5 2.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Sugar_tr PF00083.19 KEG13045.1 - 1.2e-20 73.5 7.5 1.5e-20 73.2 5.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Sugar_tr PF00083.19 KEG13046.1 - 3.9e-44 150.9 13.8 4.4e-44 150.8 9.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEG13046.1 - 0.00011 21.0 10.7 0.00015 20.6 7.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily NfeD PF01957.13 KEG13046.1 - 0.039 14.1 4.6 0.34 11.0 0.0 2.2 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding MFS_2 PF13347.1 KEG13046.1 - 0.17 10.2 5.8 0.44 8.8 0.0 2.0 2 0 0 2 2 2 0 MFS/sugar transport protein DnaJ PF00226.26 KEG13047.1 - 4.1e-28 96.9 1.7 7.1e-28 96.1 1.2 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KEG13047.1 - 5.4e-20 71.0 0.2 1.1e-17 63.6 0.0 2.3 2 0 0 2 2 2 2 DnaJ C terminal domain Ras PF00071.17 KEG13048.1 - 6.1e-48 162.2 0.2 7.3e-48 162.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEG13048.1 - 2.8e-16 60.0 0.0 4.3e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEG13048.1 - 4.7e-08 32.4 0.0 5.7e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KEG13048.1 - 8e-05 22.5 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KEG13048.1 - 0.0032 16.6 0.0 0.0048 16.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 KEG13048.1 - 0.0061 15.8 0.0 1.7 7.8 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B PduV-EutP PF10662.4 KEG13048.1 - 0.0068 15.8 0.0 0.4 10.1 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 KEG13048.1 - 0.017 14.3 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 KEG13048.1 - 0.11 12.1 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Miro PF08477.8 KEG13049.1 - 0.00096 19.6 0.0 0.0025 18.3 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AAA_14 PF13173.1 KEG13049.1 - 0.081 12.8 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arf PF00025.16 KEG13050.1 - 7.5e-66 220.6 0.2 9e-66 220.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KEG13050.1 - 1.3e-12 47.3 0.0 1.6e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KEG13050.1 - 1.3e-12 47.3 0.0 1.6e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KEG13050.1 - 1e-11 45.3 0.0 1.4e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 KEG13050.1 - 3.9e-11 42.4 0.0 5.2e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KEG13050.1 - 2.5e-10 39.5 0.4 1.8e-07 30.2 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 KEG13050.1 - 2.8e-08 33.7 0.0 3.9e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KEG13050.1 - 2e-05 24.0 0.4 0.0032 16.9 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Thioredoxin_2 PF13098.1 KEG13050.1 - 0.095 12.9 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain Fe-ADH PF00465.14 KEG13052.1 - 3e-57 193.9 0.5 3.8e-57 193.5 0.3 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 KEG13052.1 - 5.1e-27 94.7 0.0 6.9e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 KEG13052.1 - 0.00037 19.5 0.3 0.0091 14.9 0.2 2.4 1 1 0 1 1 1 1 3-dehydroquinate synthase DUF3672 PF12421.3 KEG13052.1 - 0.032 14.3 0.0 0.05 13.7 0.0 1.2 1 0 0 1 1 1 0 Fibronectin type III protein Vps54 PF07928.7 KEG13053.1 - 9.6e-32 109.9 0.1 2.4e-31 108.6 0.1 1.7 1 0 0 1 1 1 1 Vps54-like protein COG2 PF06148.6 KEG13053.1 - 0.006 16.4 0.5 0.018 14.9 0.1 2.0 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF2450 PF10475.4 KEG13053.1 - 0.048 12.5 0.0 0.11 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) 3HCDH PF00725.17 KEG13054.1 - 6.7e-09 36.0 0.0 1.1e-05 25.7 0.0 2.6 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH PF00378.15 KEG13054.1 - 2.9e-05 23.3 0.0 5.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Suc_Fer-like PF06999.7 KEG13056.1 - 7.2e-25 88.3 0.3 1.6e-24 87.2 0.2 1.6 2 0 0 2 2 2 1 Sucrase/ferredoxin-like Kelch_3 PF13415.1 KEG13057.1 - 3.4e-26 90.7 0.1 1.2e-08 34.8 0.0 5.5 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.20 KEG13057.1 - 4e-21 74.3 0.0 0.00037 19.9 0.0 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.1 KEG13057.1 - 2.7e-20 71.8 0.4 1.8e-05 24.5 0.0 6.1 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 KEG13057.1 - 3.2e-18 64.6 3.3 4.6e-05 23.0 0.0 6.5 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 KEG13057.1 - 6.8e-17 60.8 0.6 0.012 15.7 0.0 6.3 4 2 2 6 6 6 3 Kelch motif Kelch_4 PF13418.1 KEG13057.1 - 5.8e-14 51.5 5.2 0.0079 15.9 0.3 6.1 4 1 1 5 5 5 4 Galactose oxidase, central domain NUP50 PF08911.6 KEG13058.1 - 6.7e-05 23.1 0.2 6.7e-05 23.1 0.1 3.0 4 0 0 4 4 4 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.13 KEG13058.1 - 0.0007 19.6 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 RanBP1 domain CDV3 PF15359.1 KEG13058.1 - 0.017 15.1 1.4 0.043 13.9 0.9 1.6 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 Inhibitor_I71 PF12628.2 KEG13058.1 - 0.04 13.5 0.4 0.083 12.5 0.2 1.5 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor Fis1_TPR_C PF14853.1 KEG13059.1 - 1.4e-12 47.3 1.9 1.7e-11 43.8 0.4 2.3 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.12 KEG13059.1 - 0.00036 20.2 2.6 0.001 18.7 0.1 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEG13059.1 - 0.0031 17.8 0.0 12 6.2 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat HhH-GPD PF00730.20 KEG13059.1 - 0.0031 17.7 0.0 0.0072 16.5 0.0 1.6 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein TPR_11 PF13414.1 KEG13059.1 - 0.0067 16.0 0.4 0.044 13.4 0.1 2.2 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 KEG13059.1 - 0.03 13.9 0.2 0.068 12.7 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEG13059.1 - 0.035 14.7 0.3 6.1 7.7 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 KEG13059.1 - 0.11 12.6 0.0 14 6.2 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-Di19 PF05605.7 KEG13062.1 - 0.02 14.9 0.3 0.04 14.0 0.2 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding ATP_bind_3 PF01171.15 KEG13063.1 - 3.4e-17 62.5 0.0 5.1e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 PP-loop family tRNA_Me_trans PF03054.11 KEG13063.1 - 0.026 13.1 0.0 0.042 12.3 0.0 1.3 1 1 0 1 1 1 0 tRNA methyl transferase PAPS_reduct PF01507.14 KEG13063.1 - 0.054 13.3 0.0 0.15 11.8 0.0 1.8 2 1 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family DUF2392 PF10288.4 KEG13063.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2392) Cullin PF00888.17 KEG13068.1 - 1.1e-48 166.2 0.0 2.2e-48 165.1 0.0 1.4 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 KEG13068.1 - 7.5e-15 54.5 0.1 2.2e-14 53.0 0.0 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain Dynein_light PF01221.13 KEG13069.1 - 4.1e-36 122.8 0.1 4.6e-36 122.6 0.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.13 KEG13069.1 - 0.076 13.3 0.0 0.12 12.7 0.0 1.3 1 1 0 1 1 1 0 Ground-like domain HhH-GPD PF00730.20 KEG13071.1 - 1.7e-16 60.4 0.0 3.2e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.1 KEG13071.1 - 2e-08 33.6 0.0 1.4e-07 30.9 0.0 2.3 1 1 0 1 1 1 1 NUDIX domain HHH PF00633.18 KEG13071.1 - 2.7e-06 26.7 0.0 1.1e-05 24.7 0.0 2.2 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 KEG13071.1 - 0.056 13.6 0.0 0.49 10.6 0.0 2.4 1 1 1 2 2 2 0 Helix-hairpin-helix domain Transposase_20 PF02371.11 KEG13071.1 - 0.11 12.6 0.0 0.41 10.7 0.0 1.9 2 0 0 2 2 2 0 Transposase IS116/IS110/IS902 family Whib PF02467.11 KEG13071.1 - 0.16 12.2 1.4 0.37 11.1 0.1 2.2 2 0 0 2 2 2 0 Transcription factor WhiB EndIII_4Fe-2S PF10576.4 KEG13071.1 - 1.3 9.3 9.7 0.17 12.1 3.3 2.1 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III Kelch_3 PF13415.1 KEG13072.1 - 1.5e-14 53.6 7.8 1.1e-06 28.6 0.0 6.2 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_4 PF13418.1 KEG13072.1 - 5.3e-12 45.3 3.2 6.4e-09 35.4 0.0 4.6 4 1 1 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.1 KEG13072.1 - 2.5e-11 43.2 0.5 1.2e-06 28.4 0.0 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 KEG13072.1 - 9.5e-11 41.4 0.3 3.8e-07 29.8 0.0 4.0 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 KEG13072.1 - 6.3e-06 25.7 0.4 0.00031 20.3 0.0 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.20 KEG13072.1 - 5.5e-05 22.6 1.1 0.15 11.6 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Methyltransf_31 PF13847.1 KEG13073.1 - 1.1e-08 34.7 0.0 1.4e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEG13073.1 - 1.6e-07 31.6 0.0 3.3e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEG13073.1 - 7.4e-07 29.4 0.0 1.4e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEG13073.1 - 9.7e-07 29.3 0.0 1.4e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEG13073.1 - 2.5e-05 24.2 0.0 2.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEG13073.1 - 3.9e-05 23.0 0.0 5.3e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 KEG13073.1 - 0.00011 21.3 0.0 0.00018 20.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.7 KEG13073.1 - 0.00025 21.4 0.0 0.0004 20.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 KEG13073.1 - 0.0043 16.6 0.1 0.0067 16.0 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.14 KEG13073.1 - 0.006 16.1 0.0 0.0086 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.13 KEG13073.1 - 0.012 15.2 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_23 PF13489.1 KEG13073.1 - 0.014 15.1 0.0 0.031 14.0 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Sel1 PF08238.7 KEG13074.1 - 0.012 16.2 7.5 5.7 7.7 0.3 4.3 5 0 0 5 5 5 0 Sel1 repeat DUF1672 PF07901.6 KEG13074.1 - 0.041 12.8 1.7 0.069 12.1 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1672) HSL_N PF06350.7 KEG13075.1 - 0.0032 16.6 0.3 0.45 9.5 0.0 2.1 2 0 0 2 2 2 2 Hormone-sensitive lipase (HSL) N-terminus Transpep_BrtH PF14399.1 KEG13075.1 - 0.025 13.8 0.2 0.044 13.0 0.1 1.4 1 0 0 1 1 1 0 NlpC/p60-like transpeptidase ADH_zinc_N_2 PF13602.1 KEG13075.1 - 0.14 13.0 0.4 0.39 11.6 0.2 1.9 1 1 1 2 2 2 0 Zinc-binding dehydrogenase DUF515 PF04415.7 KEG13075.1 - 8 4.5 6.1 12 4.0 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) 4HBT_2 PF13279.1 KEG13076.1 - 1.6e-10 41.4 0.0 1.1e-08 35.4 0.0 2.3 2 0 0 2 2 2 2 Thioesterase-like superfamily 4HBT PF03061.17 KEG13076.1 - 5.1e-06 26.5 0.4 1.4e-05 25.1 0.1 1.9 2 0 0 2 2 2 1 Thioesterase superfamily Glycos_transf_1 PF00534.15 KEG13077.1 - 3e-12 46.3 0.0 5.9e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KEG13077.1 - 5.9e-09 36.1 0.0 1.5e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KEG13077.1 - 0.00051 20.2 0.0 0.0084 16.3 0.0 2.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 ATG16 PF08614.6 KEG13078.1 - 0.012 15.4 3.2 0.02 14.7 0.3 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Barttin PF15462.1 KEG13078.1 - 1.1 8.9 4.4 3.2 7.3 0.7 2.3 2 0 0 2 2 2 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Glyco_hydro_63 PF03200.11 KEG13080.1 - 2.1e-69 234.2 0.2 1.5e-53 181.8 0.5 3.3 1 1 1 2 2 2 2 Mannosyl oligosaccharide glucosidase eIF2A PF08662.6 KEG13083.1 - 0.054 13.2 0.0 0.074 12.7 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Pkinase PF00069.20 KEG13084.1 - 4.3e-58 196.4 0.0 5.3e-58 196.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG13084.1 - 1.1e-33 116.4 0.0 1.4e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG13084.1 - 5.3e-08 32.1 0.0 1.7e-07 30.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.6 KEG13084.1 - 0.0052 15.6 0.1 0.0073 15.1 0.1 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.18 KEG13084.1 - 0.018 14.7 0.0 1.3 8.6 0.0 2.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 KEG13084.1 - 0.024 13.9 0.0 0.037 13.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Carn_acyltransf PF00755.15 KEG13085.1 - 1.6e-159 531.7 0.0 1.9e-159 531.5 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase FKBP_C PF00254.23 KEG13086.1 - 1.7e-33 114.4 0.0 1.3e-31 108.4 0.0 2.4 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_11 PF13414.1 KEG13086.1 - 5.4e-17 61.2 1.7 3.3e-11 42.6 0.2 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KEG13086.1 - 6.2e-14 50.7 3.2 0.00084 19.0 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KEG13086.1 - 1.8e-10 39.9 1.3 0.0002 20.8 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEG13086.1 - 2.1e-08 34.5 8.6 1.4e-05 25.6 0.4 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 KEG13086.1 - 2.9e-08 33.6 5.6 0.012 16.1 0.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEG13086.1 - 9.6e-08 32.2 7.1 0.00014 22.1 2.1 2.5 1 1 2 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KEG13086.1 - 1.7e-07 31.0 2.7 0.0082 16.0 0.1 2.8 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.1 KEG13086.1 - 8.8e-06 25.5 1.4 0.00098 19.1 0.1 3.1 4 0 0 4 4 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KEG13086.1 - 2.8e-05 23.9 2.8 0.0018 18.1 0.5 3.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEG13086.1 - 6.9e-05 22.3 2.3 0.055 13.2 0.0 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEG13086.1 - 0.0002 20.9 3.5 4.7 7.2 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 KEG13086.1 - 0.00052 19.8 1.8 0.0012 18.6 1.3 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 KEG13086.1 - 0.002 18.1 2.0 0.0055 16.8 0.6 1.8 1 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KEG13086.1 - 0.0078 16.6 6.0 0.023 15.1 0.3 3.6 3 1 1 4 4 4 1 Tetratricopeptide repeat IF3_N PF05198.11 KEG13087.1 - 0.0041 17.0 0.2 0.033 14.1 0.1 2.5 2 1 0 2 2 2 1 Translation initiation factor IF-3, N-terminal domain TPT PF03151.11 KEG13088.1 - 8.9e-26 90.3 8.3 8.9e-26 90.3 5.7 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 KEG13088.1 - 8.2e-09 35.5 24.8 6e-08 32.7 4.2 2.4 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 KEG13088.1 - 6.3e-05 22.0 22.4 0.0001 21.3 15.5 1.3 1 1 0 1 1 1 1 UAA transporter family EmrE PF13536.1 KEG13088.1 - 1.5 9.0 22.1 1.1 9.5 5.3 2.8 2 1 0 2 2 2 0 Multidrug resistance efflux transporter IF4E PF01652.13 KEG13090.1 - 4.7e-38 130.3 0.0 5.9e-38 129.9 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Pkinase PF00069.20 KEG13091.1 - 5e-45 153.6 0.0 2e-43 148.4 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG13091.1 - 5.6e-24 84.6 0.0 1.5e-20 73.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 KEG13091.1 - 0.062 12.3 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEG13091.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sdh5 PF03937.11 KEG13091.1 - 0.16 11.6 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Flavinator of succinate dehydrogenase Keratin_assoc PF09775.4 KEG13093.1 - 0.087 12.3 0.6 0.12 11.9 0.4 1.2 1 0 0 1 1 1 0 Keratinocyte-associated protein 2 NAD_binding_1 PF00175.16 KEG13094.1 - 1.3e-12 48.2 0.0 4.4e-12 46.5 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.15 KEG13094.1 - 0.0022 17.4 0.0 0.095 12.1 0.0 2.3 1 1 0 1 1 1 1 FAD binding domain NAD_binding_6 PF08030.7 KEG13094.1 - 0.01 15.7 0.0 0.11 12.4 0.0 2.3 1 1 0 2 2 2 0 Ferric reductase NAD binding domain Pkinase PF00069.20 KEG13095.1 - 2.4e-66 223.5 0.0 2.9e-66 223.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG13095.1 - 5.8e-32 110.7 0.0 7.8e-32 110.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG13095.1 - 2.4e-07 30.0 0.0 6.9e-07 28.5 0.0 1.7 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 KEG13095.1 - 0.004 16.9 0.6 0.0073 16.0 0.1 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KEG13095.1 - 0.025 13.6 0.3 0.046 12.7 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PIH1 PF08190.7 KEG13096.1 - 8.8e-22 77.9 0.4 3.7e-21 75.9 0.3 1.8 1 1 0 1 1 1 1 pre-RNA processing PIH1/Nop17 MbeB_N PF04837.7 KEG13096.1 - 0.061 13.4 2.8 0.13 12.3 2.0 1.6 1 0 0 1 1 1 0 MbeB-like, N-term conserved region RNase_H PF00075.19 KEG13099.1 - 0.00047 20.5 0.0 0.00087 19.6 0.0 1.4 1 0 0 1 1 1 1 RNase H ArfGap PF01412.13 KEG13101.1 - 8.8e-31 106.1 0.1 2.3e-30 104.7 0.0 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TF_Zn_Ribbon PF08271.7 KEG13101.1 - 0.062 12.6 2.7 0.11 11.8 1.8 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding CAP_N PF01213.14 KEG13102.1 - 0.11 11.7 5.5 0.91 8.7 0.9 3.2 2 1 1 3 3 3 0 Adenylate cyclase associated (CAP) N terminal PPR_2 PF13041.1 KEG13103.1 - 2.3e-59 197.1 15.1 7.5e-10 38.6 0.0 13.6 8 3 6 14 14 14 11 PPR repeat family PPR_3 PF13812.1 KEG13103.1 - 1.1e-36 122.0 30.3 1.8e-05 24.6 0.0 15.8 17 0 0 17 17 17 9 Pentatricopeptide repeat domain PPR PF01535.15 KEG13103.1 - 3e-26 89.5 25.2 0.00047 19.9 0.0 13.3 14 1 0 14 14 14 6 PPR repeat PPR_1 PF12854.2 KEG13103.1 - 2.4e-24 84.4 21.1 0.00041 19.7 0.0 12.5 12 1 0 12 12 12 5 PPR repeat RPM2 PF08579.6 KEG13103.1 - 5.3e-07 29.7 0.0 1.4 9.1 0.0 6.1 3 2 2 5 5 5 2 Mitochondrial ribonuclease P subunit (RPM2) TPR_14 PF13428.1 KEG13103.1 - 1.4e-05 25.2 0.5 22 6.0 0.0 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat ECSIT PF06239.6 KEG13103.1 - 0.0038 16.1 2.0 13 4.5 0.0 5.6 4 2 2 6 6 6 0 Evolutionarily conserved signalling intermediate in Toll pathway TPR_16 PF13432.1 KEG13103.1 - 0.0088 16.6 2.6 42 4.9 0.0 5.0 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 KEG13103.1 - 0.029 14.2 5.7 8.3 6.4 0.0 5.1 6 1 0 6 6 6 0 Tetratricopeptide repeat TAP_C PF03943.8 KEG13103.1 - 0.085 12.2 0.0 0.88 9.0 0.0 2.6 2 0 0 2 2 2 0 TAP C-terminal domain DASH_Ask1 PF08655.5 KEG13103.1 - 0.089 12.6 0.0 0.3 10.9 0.0 1.9 1 0 0 1 1 1 0 DASH complex subunit Ask1 TPR_7 PF13176.1 KEG13103.1 - 0.11 12.2 2.0 24 5.0 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat PCI_Csn8 PF10075.4 KEG13104.1 - 4.3e-32 110.8 0.0 6.9e-32 110.1 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 KEG13104.1 - 1.1e-26 93.6 1.3 1.7e-26 93.0 0.5 1.5 1 1 1 2 2 2 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DUF2383 PF09537.5 KEG13104.1 - 0.15 12.3 0.3 5.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) DUF641 PF04859.7 KEG13105.1 - 0.0084 15.8 0.4 0.017 14.8 0.3 1.5 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) Phostensin_N PF13916.1 KEG13105.1 - 0.041 13.8 3.6 0.096 12.6 0.1 3.0 3 0 0 3 3 3 0 PP1-regulatory protein, Phostensin N-terminal Ank_2 PF12796.2 KEG13106.1 - 6.2e-17 61.7 0.2 1.2e-16 60.7 0.2 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KEG13106.1 - 8.5e-14 50.5 13.5 5.5e-08 32.2 0.6 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KEG13106.1 - 1.4e-13 50.6 3.7 5.2e-08 32.8 0.3 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEG13106.1 - 2e-11 42.9 0.8 3.6e-05 23.5 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 KEG13106.1 - 7.1e-11 42.3 0.1 1.9e-10 40.9 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) ABC2_membrane_3 PF12698.2 KEG13107.1 - 1.6e-30 106.3 43.9 1.6e-21 76.7 12.1 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.22 KEG13107.1 - 1.8e-29 102.7 0.0 1.2e-13 51.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KEG13107.1 - 6e-09 36.2 0.0 0.071 13.0 0.0 3.3 2 1 0 3 3 3 3 AAA domain AAA_16 PF13191.1 KEG13107.1 - 1.8e-05 24.8 0.1 6.7e-05 22.9 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 KEG13107.1 - 0.0066 15.9 0.0 0.017 14.6 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_19 PF13245.1 KEG13107.1 - 0.0087 15.7 0.1 0.028 14.1 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 KEG13107.1 - 0.012 15.2 0.0 0.07 12.7 0.0 2.3 2 0 0 2 2 2 0 NACHT domain SMC_N PF02463.14 KEG13107.1 - 0.017 14.3 0.0 0.24 10.5 0.0 2.5 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain DUF3584 PF12128.3 KEG13107.1 - 0.037 11.3 0.3 0.048 10.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF258 PF03193.11 KEG13107.1 - 0.062 12.4 0.1 0.15 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA PF00004.24 KEG13107.1 - 0.094 12.9 0.0 0.34 11.0 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KEG13107.1 - 0.11 12.3 0.3 0.63 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KEG13107.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KEG13107.1 - 0.13 11.6 0.2 1 8.8 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 KEG13107.1 - 0.19 11.3 0.0 0.4 10.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 KEG13107.1 - 0.27 10.9 0.1 0.53 9.9 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 KEG13107.1 - 0.4 10.3 0.0 0.82 9.3 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_15 PF13175.1 KEG13107.1 - 4.2 6.3 0.0 7.4 5.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain DUF1434 PF07254.7 KEG13108.1 - 0.0066 16.2 0.4 0.064 13.0 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1434) Colicin_V PF02674.11 KEG13108.1 - 0.015 15.1 1.1 0.8 9.5 1.4 2.2 2 0 0 2 2 2 0 Colicin V production protein Rod-binding PF10135.4 KEG13108.1 - 0.044 13.7 0.2 1.7 8.6 0.0 2.3 2 0 0 2 2 2 0 Rod binding protein MORN PF02493.15 KEG13109.1 - 1.2e-19 68.7 23.4 1.4e-07 30.8 1.6 6.6 7 0 0 7 7 7 5 MORN repeat ELO PF01151.13 KEG13110.1 - 1.4e-45 155.6 20.0 1.7e-45 155.2 13.9 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Phage_portal PF04860.7 KEG13110.1 - 0.13 10.8 0.1 2.9 6.4 0.0 2.5 3 0 0 3 3 3 0 Phage portal protein PPR_2 PF13041.1 KEG13112.1 - 3.1e-06 27.0 4.2 0.76 9.7 0.0 5.7 6 0 0 6 6 6 2 PPR repeat family PPR_3 PF13812.1 KEG13112.1 - 2.4e-05 24.2 4.2 1.5 9.2 0.0 5.6 6 0 0 6 6 6 3 Pentatricopeptide repeat domain PPR PF01535.15 KEG13112.1 - 0.011 15.6 6.7 8.6 6.5 0.0 5.2 6 0 0 6 6 6 0 PPR repeat Trp_dioxygenase PF03301.8 KEG13114.1 - 7.8e-10 38.3 0.0 0.0005 19.2 0.0 2.0 2 0 0 2 2 2 2 Tryptophan 2,3-dioxygenase Med3 PF11593.3 KEG13115.1 - 9.5 5.3 8.4 13 4.8 5.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DnaJ PF00226.26 KEG13116.1 - 7.6e-18 64.0 0.1 1.1e-17 63.4 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Galactosyl_T PF01762.16 KEG13117.1 - 1.2e-06 28.2 0.2 4.7e-05 23.0 0.0 2.9 2 1 0 3 3 3 1 Galactosyltransferase Ribonuclease_3 PF00636.21 KEG13120.1 - 0.00015 22.2 0.0 0.00037 20.9 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease III domain EF-hand_7 PF13499.1 KEG13121.1 - 0.037 14.1 0.1 0.37 10.9 0.0 2.3 2 1 1 3 3 3 0 EF-hand domain pair ADIP PF11559.3 KEG13121.1 - 0.87 9.4 13.1 0.13 12.1 5.8 1.8 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.14 KEG13121.1 - 1.6 6.5 4.1 2.5 5.8 2.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 KEG13121.1 - 4.1 6.9 16.6 0.6 9.6 8.4 1.8 2 0 0 2 2 2 0 IncA protein DUF972 PF06156.8 KEG13121.1 - 7.5 6.9 7.7 3.6 7.9 3.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF972) FAD_binding_1 PF00667.15 KEG13122.1 - 5.2e-45 153.5 0.0 9e-45 152.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KEG13122.1 - 1.5e-22 80.1 1.4 2.1e-22 79.6 0.0 1.9 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 KEG13122.1 - 3.4e-17 62.9 0.0 1.1e-16 61.3 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KEG13122.1 - 0.03 14.4 0.0 0.067 13.3 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Smg4_UPF3 PF03467.10 KEG13124.1 - 0.00019 21.5 0.0 0.19 11.6 0.0 2.4 2 1 0 2 2 2 2 Smg-4/UPF3 family TAF1D PF15333.1 KEG13124.1 - 0.0071 16.1 0.4 0.012 15.3 0.3 1.4 1 0 0 1 1 1 1 TATA box-binding protein-associated factor 1D HSP70 PF00012.15 KEG13127.1 - 4.1e-258 857.2 14.1 4.6e-258 857.0 9.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KEG13127.1 - 1.7e-19 69.5 0.6 2.1e-16 59.4 0.1 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 KEG13127.1 - 0.00019 21.1 0.0 0.00064 19.3 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 KEG13127.1 - 0.0018 17.4 0.1 0.0018 17.4 0.0 2.9 3 1 1 4 4 4 1 Hydantoinase/oxoprolinase RE_HindIII PF09518.5 KEG13127.1 - 0.068 12.0 4.3 0.076 11.9 1.3 2.2 2 0 0 2 2 2 0 HindIII restriction endonuclease zf-AN1 PF01428.11 KEG13129.1 - 3.7e-07 29.9 0.6 5.8e-07 29.2 0.4 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger DUF4407 PF14362.1 KEG13129.1 - 0.07 12.0 2.8 0.073 12.0 1.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-C2HC5 PF06221.8 KEG13129.1 - 0.081 12.6 0.3 0.11 12.2 0.2 1.2 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type ATP-synt_C PF00137.16 KEG13130.1 - 3.5e-28 97.2 34.4 1.3e-17 63.4 6.2 2.6 3 0 0 3 3 3 2 ATP synthase subunit C DUF4064 PF13273.1 KEG13130.1 - 1.1 9.3 14.0 2.1 8.5 2.5 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) Peptidase_M8 PF01457.11 KEG13131.1 - 2.1e-27 95.6 0.0 2.6e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Leishmanolysin MerT PF02411.10 KEG13131.1 - 0.16 11.8 0.6 0.28 10.9 0.4 1.4 1 0 0 1 1 1 0 MerT mercuric transport protein DUF3613 PF12266.3 KEG13132.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3613) DUF167 PF02594.11 KEG13133.1 - 1.3e-14 53.9 0.0 5.5e-11 42.2 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised ACR, YggU family COG1872 LRR_4 PF12799.2 KEG13135.1 - 5.6e-15 54.5 0.0 0.14 11.8 0.0 5.9 3 1 2 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG13135.1 - 6.5e-07 29.0 2.2 0.54 10.0 0.1 5.0 4 2 1 5 5 5 3 Leucine rich repeat LRR_1 PF00560.28 KEG13135.1 - 0.00057 19.5 1.6 54 4.4 0.0 6.5 7 2 0 7 7 7 0 Leucine Rich Repeat LRR_6 PF13516.1 KEG13135.1 - 0.013 15.5 1.2 13 6.1 0.0 5.6 8 0 0 8 8 8 0 Leucine Rich repeat Dus PF01207.12 KEG13136.1 - 2.6e-56 190.7 0.0 3.4e-56 190.3 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 KEG13136.1 - 0.0033 16.7 0.0 0.0097 15.1 0.0 1.7 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.9 KEG13136.1 - 0.0037 16.3 0.1 0.0063 15.6 0.0 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG NMO PF03060.10 KEG13136.1 - 0.01 15.0 0.2 0.016 14.3 0.1 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase TMP-TENI PF02581.12 KEG13136.1 - 0.035 13.2 0.0 0.084 11.9 0.0 1.7 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI F_bP_aldolase PF01116.15 KEG13136.1 - 0.1 11.6 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-II DHO_dh PF01180.16 KEG13136.1 - 0.12 11.3 0.0 1.5 7.6 0.0 2.1 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase DUF1042 PF06294.6 KEG13138.1 - 4.4e-31 107.5 0.0 6.3e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1042) CAMSAP_CH PF11971.3 KEG13138.1 - 1.3e-26 92.0 0.0 2.1e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 CAMSAP CH domain CH PF00307.26 KEG13138.1 - 1.5e-06 28.2 0.0 2.7e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Phage_lysis PF03245.8 KEG13138.1 - 0.0097 15.8 0.2 0.22 11.5 0.0 2.3 2 0 0 2 2 2 1 Bacteriophage Rz lysis protein TMF_DNA_bd PF12329.3 KEG13138.1 - 0.051 13.3 4.6 2.9 7.7 1.5 2.8 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SBDS_C PF09377.5 KEG13139.1 - 5.9e-30 103.5 0.1 1.3e-29 102.3 0.1 1.6 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 KEG13139.1 - 3.9e-25 87.4 0.5 7.6e-25 86.5 0.4 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein DUF3446 PF11928.3 KEG13140.1 - 0.41 10.8 4.2 0.78 9.9 2.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) Nab1 PF04902.7 KEG13141.1 - 0.033 13.6 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 Conserved region in Nab1 Acyltransferase PF01553.16 KEG13142.1 - 3.7e-17 62.0 0.0 8.8e-17 60.7 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase Lipase_3 PF01764.20 KEG13143.1 - 4.3e-05 23.1 0.0 0.00015 21.3 0.0 1.9 2 0 0 2 2 2 1 Lipase (class 3) DUF21 PF01595.15 KEG13143.1 - 0.011 15.0 0.1 0.011 15.0 0.0 2.5 4 0 0 4 4 4 0 Domain of unknown function DUF21 Abhydrolase_5 PF12695.2 KEG13143.1 - 0.012 15.3 0.0 0.029 14.1 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEG13143.1 - 0.013 15.3 0.0 0.039 13.8 0.0 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 KEG13143.1 - 0.022 14.3 0.1 0.073 12.6 0.0 1.9 2 0 0 2 2 2 0 PGAP1-like protein UPF0227 PF05728.7 KEG13143.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF2974 PF11187.3 KEG13143.1 - 0.24 10.7 0.6 1.5 8.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) FHA PF00498.21 KEG13144.1 - 0.00029 20.8 0.0 0.0017 18.4 0.0 2.3 3 0 0 3 3 3 1 FHA domain WWE PF02825.15 KEG13144.1 - 0.00047 19.5 0.4 0.0037 16.6 0.0 2.2 2 0 0 2 2 2 1 WWE domain Nucleoplasmin PF03066.10 KEG13144.1 - 0.77 9.2 19.6 0.048 13.1 5.2 3.0 2 1 0 2 2 2 0 Nucleoplasmin UQ_con PF00179.21 KEG13145.1 - 4.8e-23 81.1 0.0 6.3e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KEG13145.1 - 0.026 14.4 0.0 0.084 12.7 0.0 1.7 1 1 0 1 1 1 0 RWD domain Prok-E2_B PF14461.1 KEG13145.1 - 0.049 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family B RRM_1 PF00076.17 KEG13146.1 - 1.1e-05 24.9 0.0 0.00072 19.1 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG13146.1 - 0.002 18.0 0.0 0.0047 16.8 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KEG13146.1 - 0.015 14.9 0.0 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 Limkain b1 RRM_5 PF13893.1 KEG13146.1 - 0.14 12.0 0.0 0.34 10.7 0.0 1.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF-3c_N PF05470.7 KEG13147.1 - 2.2e-21 75.5 18.5 1.2e-17 63.2 0.6 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 KEG13147.1 - 0.0093 16.2 0.0 0.045 14.0 0.0 2.3 1 0 0 1 1 1 1 PCI domain Methyltransf_23 PF13489.1 KEG13149.1 - 0.0098 15.6 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain FlaC_arch PF05377.6 KEG13150.1 - 7.3 6.5 8.7 14 5.6 0.1 3.9 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) FA_desaturase PF00487.19 KEG13151.1 - 3.9e-34 118.2 14.4 6.8e-34 117.4 10.0 1.4 1 0 0 1 1 1 1 Fatty acid desaturase PET PF06297.9 KEG13151.1 - 0.024 14.3 0.0 2.9 7.6 0.0 2.3 2 0 0 2 2 2 0 PET Domain Thioredoxin PF00085.15 KEG13152.1 - 2.6e-63 210.2 1.1 1.9e-32 111.0 0.0 4.2 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.1 KEG13152.1 - 1.8e-34 119.1 0.3 5.1e-23 81.8 0.0 4.1 3 2 2 5 5 5 4 Thioredoxin-like domain Thioredoxin_2 PF13098.1 KEG13152.1 - 7.8e-15 55.0 3.3 8.5e-08 32.3 0.1 4.7 4 2 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KEG13152.1 - 2.8e-13 49.6 0.0 8.5e-06 25.7 0.0 3.6 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.1 KEG13152.1 - 8.2e-11 41.8 1.2 0.0043 17.1 0.1 4.6 4 2 1 5 5 5 2 Thioredoxin-like AhpC-TSA PF00578.16 KEG13152.1 - 2.9e-07 30.2 0.6 0.0021 17.7 0.0 3.1 2 1 1 3 3 3 2 AhpC/TSA family ERp29_N PF07912.8 KEG13152.1 - 1.3e-06 28.3 0.2 0.0042 17.0 0.0 3.7 4 0 0 4 4 4 1 ERp29, N-terminal domain Redoxin PF08534.5 KEG13152.1 - 1.4e-05 24.7 0.4 0.017 14.6 0.0 3.2 3 0 0 3 3 3 2 Redoxin Thioredoxin_4 PF13462.1 KEG13152.1 - 0.00022 21.2 0.4 0.071 13.1 0.0 3.4 2 1 1 3 3 3 1 Thioredoxin Thioredoxin_3 PF13192.1 KEG13152.1 - 0.00032 20.4 0.0 0.14 11.9 0.0 2.7 2 0 0 2 2 2 1 Thioredoxin domain TraF PF13728.1 KEG13152.1 - 0.0025 17.3 0.0 0.12 11.8 0.0 2.7 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.1 KEG13152.1 - 0.0078 15.7 0.1 3.8 7.0 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin HyaE PF07449.6 KEG13152.1 - 0.061 13.2 0.0 1.4 8.8 0.0 3.0 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE NuA4 PF09340.5 KEG13153.1 - 0.2 11.3 2.4 0.5 10.0 1.6 1.7 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 zf-H2C2_2 PF13465.1 KEG13155.1 - 0.04 14.2 1.4 0.088 13.1 0.9 1.6 1 0 0 1 1 1 0 Zinc-finger double domain SSB PF00436.20 KEG13155.1 - 0.049 13.5 0.0 0.13 12.1 0.0 1.6 2 0 0 2 2 2 0 Single-strand binding protein family Ribosomal_L1 PF00687.16 KEG13156.1 - 3.2e-16 59.3 0.0 4.4e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Cpn60_TCP1 PF00118.19 KEG13157.1 - 3e-135 451.5 9.4 3.4e-135 451.4 6.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family LRR_4 PF12799.2 KEG13158.1 - 1.3e-07 31.0 0.3 0.00028 20.4 0.0 2.7 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG13158.1 - 0.016 14.9 0.1 0.04 13.6 0.1 1.7 1 0 0 1 1 1 0 Leucine rich repeat LRR_1 PF00560.28 KEG13158.1 - 0.04 13.9 0.2 71 4.0 0.0 4.1 3 0 0 3 3 3 0 Leucine Rich Repeat Nucleoporin_N PF08801.6 KEG13159.1 - 2e-61 208.0 0.0 2.9e-61 207.4 0.0 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.9 KEG13159.1 - 8.8e-14 50.9 3.7 2.4e-13 49.4 2.6 1.7 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Bromodomain PF00439.20 KEG13161.1 - 1.9e-13 50.1 0.0 3.5e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Bromodomain EVE PF01878.13 KEG13163.1 - 2.4e-52 176.7 0.0 2.7e-52 176.5 0.0 1.0 1 0 0 1 1 1 1 EVE domain Ank PF00023.25 KEG13164.1 - 0.23 11.3 0.7 0.92 9.4 0.4 2.0 2 0 0 2 2 2 0 Ankyrin repeat AAA_33 PF13671.1 KEG13165.1 - 5.3e-13 49.0 0.0 1.7e-12 47.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain RNA_lig_T4_1 PF09511.5 KEG13165.1 - 2.4e-12 46.8 0.0 5.9e-12 45.5 0.0 1.7 2 0 0 2 2 1 1 RNA ligase AAA_18 PF13238.1 KEG13165.1 - 1.7e-09 38.0 0.0 3.5e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEG13165.1 - 8.4e-05 23.3 0.1 0.002 18.9 0.0 2.9 3 0 0 3 3 2 1 AAA domain NACHT PF05729.7 KEG13165.1 - 0.0015 18.2 0.0 0.0035 17.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA PF00004.24 KEG13165.1 - 0.0015 18.7 0.0 0.0041 17.3 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEG13165.1 - 0.0024 18.0 0.0 0.031 14.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KEG13165.1 - 0.016 14.2 0.0 0.036 13.0 0.0 1.5 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KEG13165.1 - 0.018 15.0 0.1 0.1 12.6 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.9 KEG13165.1 - 0.036 13.7 0.0 0.095 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 KEG13165.1 - 0.044 12.8 0.0 0.078 12.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.18 KEG13165.1 - 0.047 13.6 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase NB-ARC PF00931.17 KEG13165.1 - 0.077 11.8 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain IstB_IS21 PF01695.12 KEG13165.1 - 0.078 12.3 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 KEG13165.1 - 0.094 11.8 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 KEG13165.1 - 0.094 12.2 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 KEG13165.1 - 0.11 11.6 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF258 PF03193.11 KEG13165.1 - 0.11 11.6 0.0 0.26 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Sigma54_activat PF00158.21 KEG13165.1 - 0.13 11.7 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain NTPase_1 PF03266.10 KEG13165.1 - 0.14 11.8 0.0 0.38 10.4 0.0 1.8 1 1 0 1 1 1 0 NTPase Transposase_20 PF02371.11 KEG13165.1 - 0.22 11.6 1.0 1.5 8.9 0.7 2.3 1 1 0 1 1 1 0 Transposase IS116/IS110/IS902 family Rsa3 PF14615.1 KEG13166.1 - 0.11 11.8 0.0 0.18 11.0 0.0 1.5 1 1 0 1 1 1 0 Ribosome-assembly protein 3 Ribosomal_S21e PF01249.13 KEG13167.1 - 8.4e-31 105.7 0.1 1.2e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S21e DUF1147 PF06615.6 KEG13167.1 - 0.03 14.1 0.3 6.2 6.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1147) MIT PF04212.13 KEG13168.1 - 0.0073 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Peptidase_C11 PF03415.9 KEG13171.1 - 5.3e-09 35.5 0.2 7.2e-09 35.1 0.2 1.2 1 0 0 1 1 1 1 Clostripain family CarD_CdnL_TRCF PF02559.11 KEG13171.1 - 0.14 12.2 0.4 4.5 7.3 0.0 2.4 2 0 0 2 2 2 0 CarD-like/TRCF domain ERM PF00769.14 KEG13172.1 - 0.0028 17.2 3.0 0.0028 17.2 2.1 3.2 2 1 1 3 3 3 1 Ezrin/radixin/moesin family UXS1_N PF11803.3 KEG13172.1 - 0.12 12.1 0.3 0.77 9.5 0.1 2.4 3 0 0 3 3 3 0 UDP-glucuronate decarboxylase N-terminal AAA_13 PF13166.1 KEG13172.1 - 1.7 7.0 20.6 1.2 7.5 7.1 2.0 2 0 0 2 2 2 0 AAA domain ArsA_ATPase PF02374.10 KEG13173.1 - 1.2e-92 310.1 0.0 1.7e-92 309.7 0.0 1.2 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 KEG13173.1 - 3.8e-12 46.0 3.2 4.6e-11 42.4 2.2 2.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.1 KEG13173.1 - 8.6e-06 25.2 0.2 6.7e-05 22.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_31 PF13614.1 KEG13173.1 - 0.0028 17.6 0.0 0.054 13.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 KEG13173.1 - 0.016 14.6 0.2 0.78 9.1 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Fer4_NifH PF00142.13 KEG13173.1 - 0.023 13.8 0.0 0.27 10.3 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Tape_meas_lam_C PF09718.5 KEG13173.1 - 0.033 14.0 0.2 0.081 12.8 0.1 1.6 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) NB-ARC PF00931.17 KEG13173.1 - 0.06 12.1 0.6 0.098 11.4 0.1 1.4 2 0 0 2 2 2 0 NB-ARC domain MFS_1 PF07690.11 KEG13174.1 - 3.8e-16 58.7 34.0 9.1e-13 47.6 12.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 KEG13174.1 - 1.2e-09 37.7 16.6 1.2e-09 37.7 11.5 2.8 2 1 0 2 2 2 1 Nodulin-like YajC PF02699.10 KEG13174.1 - 0.27 10.9 2.0 0.32 10.6 0.0 2.2 2 0 0 2 2 2 0 Preprotein translocase subunit DASH_Spc19 PF08287.6 KEG13175.1 - 0.0076 15.8 0.2 0.012 15.1 0.2 1.3 1 0 0 1 1 1 1 Spc19 EphA2_TM PF14575.1 KEG13175.1 - 0.11 12.9 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Tweety PF04906.8 KEG13175.1 - 0.14 10.4 0.0 0.2 10.0 0.0 1.1 1 0 0 1 1 1 0 Tweety Ank_2 PF12796.2 KEG13176.1 - 1e-26 93.0 0.1 4.3e-10 39.7 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KEG13176.1 - 2.1e-21 74.5 0.8 3.6e-05 23.3 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 KEG13176.1 - 5.1e-21 74.6 0.6 4.6e-07 30.1 0.0 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEG13176.1 - 3.6e-18 65.1 2.9 5.3e-06 26.5 0.0 3.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEG13176.1 - 3.5e-12 45.2 0.0 0.0021 18.1 0.0 5.4 5 0 0 5 5 5 2 Ankyrin repeat TilS_C PF11734.3 KEG13176.1 - 0.085 12.0 0.0 1.7 7.9 0.0 2.2 2 0 0 2 2 2 0 TilS substrate C-terminal domain MFS_1 PF07690.11 KEG13177.1 - 8e-22 77.4 31.5 3.1e-16 59.0 13.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 KEG13177.1 - 5.4e-06 25.8 20.6 5.4e-06 25.8 14.2 2.8 2 1 0 2 2 2 1 Nodulin-like Ribosomal_S4 PF00163.14 KEG13177.1 - 0.13 12.6 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S4/S9 N-terminal domain Oleosin PF01277.12 KEG13177.1 - 1 8.9 0.0 1 8.9 0.0 3.9 4 0 0 4 4 4 0 Oleosin WD40 PF00400.27 KEG13178.1 - 2.1e-17 62.2 7.3 6e-06 25.9 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat BTB_2 PF02214.17 KEG13178.1 - 6.2e-15 55.1 0.0 2.1e-13 50.2 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain MMS1_N PF10433.4 KEG13178.1 - 0.021 12.9 0.0 0.032 12.3 0.0 1.2 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term AAA_16 PF13191.1 KEG13178.1 - 0.022 14.7 2.3 0.05 13.5 0.4 2.1 1 1 1 2 2 2 0 AAA ATPase domain PQQ_3 PF13570.1 KEG13178.1 - 0.096 12.9 4.9 1.4 9.2 0.0 4.3 5 0 0 5 5 5 0 PQQ-like domain Peptidase_M16 PF00675.15 KEG13178.1 - 0.14 11.9 0.7 0.48 10.1 0.0 2.0 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) MFS_1 PF07690.11 KEG13179.1 - 1.2e-15 57.0 30.5 1.5e-14 53.5 13.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 KEG13179.1 - 3.8e-07 29.6 13.6 3.8e-07 29.6 9.4 2.8 2 2 0 2 2 2 1 Nodulin-like DUF1129 PF06570.6 KEG13179.1 - 0.26 10.5 7.8 0.43 9.8 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) 60KD_IMP PF02096.15 KEG13179.1 - 0.58 9.7 5.0 2 8.0 0.7 3.2 1 1 1 2 2 2 0 60Kd inner membrane protein MFS_1 PF07690.11 KEG13180.1 - 2.2e-11 43.0 35.1 1.5e-09 37.1 17.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 KEG13180.1 - 1.6e-10 40.6 16.3 1.6e-10 40.6 11.3 2.3 2 1 0 2 2 2 1 Nodulin-like SP_C-Propep PF08999.5 KEG13180.1 - 0.5 9.8 4.0 0.4 10.2 0.3 2.8 3 0 0 3 3 3 0 Surfactant protein C, N terminal propeptide Ribosomal_L24e PF01246.15 KEG13182.1 - 1.5e-29 101.5 1.4 1.5e-29 101.5 1.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L24e Toxin_2 PF00451.14 KEG13182.1 - 0.1 12.7 1.0 0.16 12.0 0.7 1.4 1 0 0 1 1 1 0 Scorpion short toxin, BmKK2 zf-FCS PF06467.9 KEG13182.1 - 0.18 11.4 5.1 0.3 10.7 3.6 1.3 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif zf-ribbon_3 PF13248.1 KEG13182.1 - 0.53 9.5 2.9 0.99 8.7 2.0 1.5 1 0 0 1 1 1 0 zinc-ribbon domain YqzE PF14038.1 KEG13182.1 - 4.1 7.2 7.5 6.4 6.6 0.3 2.5 2 0 0 2 2 2 0 YqzE-like protein LRR_4 PF12799.2 KEG13183.1 - 1.6e-20 72.2 17.0 0.00028 20.4 0.0 10.4 7 3 5 12 12 12 7 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KEG13183.1 - 8e-20 68.6 22.9 0.82 9.9 0.0 14.7 15 1 1 16 16 16 6 Leucine Rich repeat LRR_1 PF00560.28 KEG13183.1 - 3.3e-15 53.7 23.9 1.1 9.5 0.0 14.1 15 0 0 15 15 15 4 Leucine Rich Repeat LRR_8 PF13855.1 KEG13183.1 - 1.2e-10 40.9 19.7 0.04 13.6 0.0 10.0 9 2 2 11 11 11 5 Leucine rich repeat LRR_7 PF13504.1 KEG13183.1 - 4.8e-10 37.9 23.5 7.2 7.2 0.0 13.7 15 0 0 15 15 15 2 Leucine rich repeat START PF01852.14 KEG13185.1 - 7.5e-17 61.3 0.0 1.1e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 START domain Kinesin PF00225.18 KEG13186.1 - 4.6e-92 308.2 0.0 7e-92 307.6 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain MIF4G PF02854.14 KEG13187.1 - 5.2e-05 22.7 0.0 0.011 15.1 0.0 3.0 3 0 0 3 3 3 2 MIF4G domain HEAT PF02985.17 KEG13188.1 - 4.9e-08 32.4 0.5 0.002 18.0 0.0 5.2 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 KEG13188.1 - 0.002 18.5 0.7 0.002 18.5 0.5 5.7 5 0 0 5 5 5 1 HEAT-like repeat HEAT_2 PF13646.1 KEG13188.1 - 0.0021 18.3 3.5 0.0021 18.3 2.4 5.3 5 1 1 6 6 6 1 HEAT repeats Adaptin_N PF01602.15 KEG13188.1 - 0.0039 15.5 0.1 0.022 13.1 0.0 2.3 2 0 0 2 2 2 1 Adaptin N terminal region T2SM PF04612.7 KEG13189.1 - 1.4 8.6 6.3 0.43 10.3 2.0 1.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M DUF4359 PF14271.1 KEG13190.1 - 0.26 11.6 6.1 0.23 11.8 0.8 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4359) PAXNEB PF05625.6 KEG13190.1 - 8 5.1 10.3 5.7 5.6 5.9 1.5 1 1 0 1 1 1 0 PAXNEB protein Abhydrolase_6 PF12697.2 KEG13191.1 - 8e-06 25.8 0.0 1.4e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEG13191.1 - 0.0017 17.9 0.0 0.0021 17.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KEG13191.1 - 0.15 11.2 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 KEG13192.1 - 1.2e-06 28.2 0.0 1.7e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_6 PF12697.2 KEG13192.1 - 6.6e-06 26.1 0.0 9.5e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEG13192.1 - 0.0059 16.3 0.0 0.0083 15.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Herpes_UL7 PF01677.11 KEG13192.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.5 2 0 0 2 2 2 0 Herpesvirus UL7 like zf-C2H2_jaz PF12171.3 KEG13193.1 - 5.4e-08 32.7 3.5 8.5e-08 32.1 2.5 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KEG13193.1 - 2.4e-06 27.5 1.4 3.6e-06 26.9 0.9 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KEG13193.1 - 0.0014 18.7 0.1 0.0029 17.6 0.1 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 KEG13193.1 - 0.11 12.9 0.7 0.17 12.3 0.5 1.3 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-DNL PF05180.7 KEG13194.1 - 5.7e-29 99.6 0.7 8.6e-29 99.0 0.5 1.3 1 0 0 1 1 1 1 DNL zinc finger CGGC PF08821.6 KEG13194.1 - 0.0022 18.0 0.1 0.0035 17.4 0.1 1.3 1 0 0 1 1 1 1 CGGC domain DUF2325 PF10087.4 KEG13194.1 - 0.0085 15.9 0.4 0.024 14.4 0.3 1.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2325) DUF1364 PF07102.7 KEG13194.1 - 0.015 15.1 1.8 0.017 14.9 0.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1364) HET-s_218-289 PF11558.3 KEG13194.1 - 0.042 13.8 0.0 0.086 12.8 0.0 1.5 1 0 0 1 1 1 0 Het-s 218-289 Zn_ribbon_recom PF13408.1 KEG13194.1 - 0.075 13.3 0.2 0.17 12.1 0.1 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Elf1 PF05129.8 KEG13194.1 - 0.078 12.6 0.6 0.14 11.9 0.4 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-CSL PF05207.8 KEG13194.1 - 0.089 12.3 0.5 0.18 11.3 0.3 1.4 1 0 0 1 1 1 0 CSL zinc finger zinc_ribbon_4 PF13717.1 KEG13194.1 - 0.11 12.2 0.3 6.1 6.6 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Gin PF10764.4 KEG13194.1 - 0.51 10.0 2.5 2.2 8.0 0.0 2.4 1 1 1 2 2 2 0 Inhibitor of sigma-G Gin ParcG PF10274.4 KEG13195.1 - 2e-77 259.2 0.0 2.4e-77 258.9 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein PCI PF01399.22 KEG13196.1 - 2.2e-14 53.6 0.0 5.1e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 KEG13196.1 - 0.037 13.7 0.0 0.092 12.5 0.0 1.7 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 His_Phos_2 PF00328.17 KEG13197.1 - 1.5e-15 57.3 0.0 6.2e-14 52.0 0.0 2.4 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 KEG13197.1 - 0.0066 16.5 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Apolipoprotein PF01442.13 KEG13198.1 - 0.0046 16.4 9.7 0.011 15.2 6.7 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Chalcone PF02431.10 KEG13198.1 - 0.098 12.0 2.3 0.18 11.1 1.6 1.3 1 0 0 1 1 1 0 Chalcone-flavanone isomerase Rnk_N PF14760.1 KEG13198.1 - 0.11 12.5 1.2 0.87 9.7 0.1 2.9 3 0 0 3 3 3 0 Rnk N-terminus Phasin PF05597.6 KEG13198.1 - 0.13 12.0 8.8 0.13 12.0 0.9 3.1 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Fib_alpha PF08702.5 KEG13198.1 - 0.15 12.2 11.4 0.12 12.5 1.3 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4404 PF14357.1 KEG13198.1 - 0.18 12.2 10.8 2.1 8.8 0.9 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Baculo_PEP_C PF04513.7 KEG13198.1 - 0.91 9.3 8.9 7.3 6.4 1.1 3.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF883 PF05957.8 KEG13198.1 - 3.9 7.9 6.9 0.61 10.5 0.5 2.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) HR1 PF02185.11 KEG13198.1 - 6.4 6.6 9.9 11 5.8 1.7 3.2 2 1 0 2 2 2 0 Hr1 repeat Pex2_Pex12 PF04757.9 KEG13199.1 - 2.7e-34 118.5 7.2 3.4e-34 118.2 5.0 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.20 KEG13199.1 - 0.00025 20.6 9.6 0.00044 19.8 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TF_Zn_Ribbon PF08271.7 KEG13199.1 - 0.0058 15.9 0.3 0.014 14.7 0.2 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding zf-C3HC4_2 PF13923.1 KEG13199.1 - 0.011 15.7 10.8 0.02 14.9 7.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEG13199.1 - 0.013 15.2 7.9 0.03 14.0 5.5 1.6 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KEG13199.1 - 0.013 15.1 8.7 0.021 14.5 6.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEG13199.1 - 0.039 13.7 8.6 0.081 12.7 5.9 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.1 KEG13199.1 - 0.039 13.8 9.7 0.043 13.7 5.7 1.9 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Siva PF05458.7 KEG13199.1 - 0.074 12.6 2.4 0.13 11.8 1.7 1.3 1 0 0 1 1 1 0 Cd27 binding protein (Siva) DUF3538 PF12057.3 KEG13199.1 - 0.12 11.9 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3538) zf-RING_UBOX PF13445.1 KEG13199.1 - 0.3 10.8 3.2 0.55 10.0 2.2 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.1 KEG13199.1 - 0.3 10.6 5.7 0.19 11.2 1.1 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 PHD PF00628.24 KEG13200.1 - 0.0011 18.6 10.6 0.0011 18.6 7.4 2.4 2 1 0 2 2 2 1 PHD-finger zf-DHHC PF01529.15 KEG13205.1 - 1.1e-34 119.2 1.0 1.4e-34 118.9 0.1 1.6 1 1 0 1 1 1 1 DHHC palmitoyltransferase Pex2_Pex12 PF04757.9 KEG13206.1 - 1.2e-17 64.0 3.4 2.1e-10 40.4 0.0 2.1 1 1 1 2 2 2 2 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 KEG13206.1 - 4e-09 36.1 6.8 6.5e-09 35.4 4.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KEG13206.1 - 1.1e-08 34.9 8.3 1.8e-08 34.2 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEG13206.1 - 2.1e-08 33.7 5.0 3.3e-08 33.0 3.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEG13206.1 - 9.1e-08 31.6 6.8 1.4e-07 31.0 4.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEG13206.1 - 9.8e-08 31.6 5.8 1.6e-07 30.9 4.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KEG13206.1 - 1.4e-06 28.0 6.9 2.3e-06 27.3 4.8 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KEG13206.1 - 0.0001 22.3 3.8 0.00017 21.6 2.7 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KEG13206.1 - 0.00012 21.7 2.2 0.00021 21.0 1.5 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KEG13206.1 - 0.0017 18.0 3.7 0.0036 17.0 2.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger TerY-C PF15616.1 KEG13206.1 - 0.006 16.5 0.4 0.009 15.9 0.3 1.2 1 0 0 1 1 1 1 TerY-C metal binding domain zf-RING_6 PF14835.1 KEG13206.1 - 0.056 13.2 2.8 0.14 11.9 2.0 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 KEG13206.1 - 0.11 12.0 5.6 0.36 10.3 3.9 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 KEG13206.1 - 0.12 11.9 6.2 0.24 11.0 4.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 KEG13206.1 - 0.14 11.7 0.4 0.23 11.0 0.3 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 KEG13206.1 - 0.16 11.9 6.0 0.99 9.4 4.2 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain IBR PF01485.16 KEG13206.1 - 0.72 9.7 7.3 0.56 10.1 3.8 1.8 1 1 0 1 1 1 0 IBR domain LRR_8 PF13855.1 KEG13207.1 - 1.3e-10 40.8 1.6 4.9e-06 26.2 0.1 2.2 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 KEG13207.1 - 2.2e-07 30.3 4.2 2.5e-06 26.9 0.1 2.3 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) EF-hand_6 PF13405.1 KEG13207.1 - 0.0002 21.0 0.0 0.025 14.4 0.0 3.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 KEG13207.1 - 0.00021 20.3 0.0 0.0022 17.1 0.0 2.7 3 0 0 3 3 3 1 EF hand LRR_7 PF13504.1 KEG13207.1 - 0.00045 19.9 0.1 1.2 9.6 0.0 3.7 2 0 0 2 2 2 1 Leucine rich repeat EF-hand_7 PF13499.1 KEG13207.1 - 0.0005 20.1 0.0 0.0018 18.3 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain pair LRR_1 PF00560.28 KEG13207.1 - 0.014 15.3 0.2 13 6.2 0.0 3.2 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_6 PF13516.1 KEG13207.1 - 0.025 14.6 0.0 2.8 8.2 0.0 3.0 1 1 1 2 2 2 0 Leucine Rich repeat ATG16 PF08614.6 KEG13207.1 - 0.042 13.6 0.4 0.094 12.5 0.2 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) EF-hand_8 PF13833.1 KEG13207.1 - 0.071 12.7 0.0 0.31 10.6 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain pair Cep57_CLD_2 PF14197.1 KEG13207.1 - 0.16 11.8 3.9 0.83 9.6 0.2 3.0 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 VPS9 PF02204.13 KEG13210.1 - 4.8e-12 45.8 0.0 9.2e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain MORN PF02493.15 KEG13210.1 - 2.2e-05 23.8 6.9 0.0013 18.3 0.0 5.3 6 0 0 6 6 6 1 MORN repeat Pkinase PF00069.20 KEG13211.1 - 2.3e-65 220.3 0.0 3e-65 219.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG13211.1 - 7e-37 126.8 0.0 9.1e-37 126.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG13211.1 - 1.7e-06 27.2 0.0 4.5e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KEG13211.1 - 0.1 12.3 0.0 0.73 9.5 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family SUZ PF12752.2 KEG13213.1 - 3.7 8.1 6.2 38 4.9 0.0 3.5 3 1 0 3 3 3 0 SUZ domain Ead_Ea22 PF13935.1 KEG13214.1 - 0.31 11.3 5.2 0.63 10.3 2.4 2.2 2 0 0 2 2 2 0 Ead/Ea22-like protein FUSC PF04632.7 KEG13215.1 - 5.7 5.2 5.4 0.83 8.0 0.2 1.8 2 0 0 2 2 2 0 Fusaric acid resistance protein family PRMT5 PF05185.11 KEG13216.1 - 1.8e-73 248.0 0.0 2.4e-73 247.6 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Cyt-b5 PF00173.23 KEG13217.1 - 4.5e-09 35.9 0.0 6.8e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain E1_dh PF00676.15 KEG13218.1 - 4.6e-84 281.6 1.6 5.8e-50 169.7 0.0 2.1 1 1 1 2 2 2 2 Dehydrogenase E1 component DXP_synthase_N PF13292.1 KEG13218.1 - 0.00058 18.8 1.4 1.8 7.4 0.1 3.4 2 1 1 3 3 3 3 1-deoxy-D-xylulose-5-phosphate synthase DUF393 PF04134.7 KEG13219.1 - 2.1e-05 25.5 4.9 0.0039 18.2 3.4 2.3 1 1 0 1 1 1 1 Protein of unknown function, DUF393 DUF971 PF06155.7 KEG13220.1 - 3.2e-17 62.7 0.0 6.7e-17 61.6 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF971) DUF2442 PF10387.4 KEG13220.1 - 0.011 15.7 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2442) zf-DHHC PF01529.15 KEG13221.1 - 1.8e-30 105.5 8.6 1.8e-30 105.5 6.0 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase PB1 PF00564.19 KEG13225.1 - 6.8e-06 25.6 0.1 2.5e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 PB1 domain DNA_pol_viral_N PF00242.12 KEG13225.1 - 0.61 9.0 5.7 1.4 7.8 3.9 1.6 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain V-ATPase_H_N PF03224.9 KEG13226.1 - 2.4e-68 230.5 0.0 3.9e-68 229.8 0.0 1.3 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 KEG13226.1 - 2.4e-46 156.5 0.4 1.5e-44 150.7 0.0 2.6 3 0 0 3 3 3 1 V-ATPase subunit H zf-HC2 PF13490.1 KEG13226.1 - 0.16 11.9 0.4 3.6 7.6 0.0 2.8 3 0 0 3 3 3 0 Putative zinc-finger Peptidase_M8 PF01457.11 KEG13227.1 - 7.4e-115 384.2 9.2 5e-59 200.0 2.9 2.1 2 0 0 2 2 2 2 Leishmanolysin Glycos_transf_1 PF00534.15 KEG13231.1 - 1.2e-33 115.9 0.0 2e-33 115.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KEG13231.1 - 8e-07 29.2 0.0 1.7e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KEG13231.1 - 2.7e-06 27.5 0.0 6.6e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 TPR_11 PF13414.1 KEG13232.1 - 2.1e-34 116.9 18.7 2.5e-16 59.0 0.8 6.1 3 3 3 6 6 6 4 TPR repeat TPR_1 PF00515.23 KEG13232.1 - 2.8e-25 86.8 23.5 2.8e-07 29.8 0.0 7.8 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.12 KEG13232.1 - 4.2e-21 73.0 26.5 0.00059 19.5 0.0 9.2 9 1 0 9 9 9 5 Tetratricopeptide repeat DnaJ PF00226.26 KEG13232.1 - 5.8e-20 70.7 0.1 1.5e-19 69.4 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_19 PF14559.1 KEG13232.1 - 1.6e-12 47.6 8.2 0.058 13.7 0.0 6.1 4 2 2 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 KEG13232.1 - 1.5e-10 41.4 28.1 0.00013 22.4 0.2 7.5 5 2 1 7 7 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 KEG13232.1 - 4.3e-10 39.3 14.8 0.0004 20.2 0.1 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 KEG13232.1 - 2.3e-09 36.6 9.3 0.072 13.3 0.0 6.2 6 2 1 7 7 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 KEG13232.1 - 1.1e-06 27.9 12.0 0.0082 15.8 0.0 5.9 7 0 0 7 7 7 2 Tetratricopeptide repeat Rapsyn_N PF10579.4 KEG13232.1 - 1.4e-06 27.9 0.7 0.00019 21.1 0.0 3.3 3 0 0 3 3 3 1 Rapsyn N-terminal myristoylation and linker region Apc3 PF12895.2 KEG13232.1 - 2.3e-06 27.6 15.4 0.08 13.0 0.8 4.7 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 KEG13232.1 - 1.7e-05 25.0 25.5 0.25 12.0 0.1 8.9 4 3 6 10 10 10 3 Tetratricopeptide repeat TPR_7 PF13176.1 KEG13232.1 - 0.00012 21.6 9.4 0.37 10.6 0.0 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 KEG13232.1 - 0.0034 17.7 14.3 0.75 10.3 0.2 6.3 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 KEG13232.1 - 0.006 16.4 13.7 0.0068 16.2 0.1 5.1 4 2 2 6 6 5 2 Tetratricopeptide repeat MIT PF04212.13 KEG13232.1 - 0.025 14.4 8.9 12 5.8 0.0 5.2 5 1 0 5 5 5 0 MIT (microtubule interacting and transport) domain Zn_Tnp_IS1595 PF12760.2 KEG13233.1 - 0.075 12.8 0.9 0.15 11.8 0.6 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Sec7 PF01369.15 KEG13234.1 - 1e-45 155.7 0.0 1.8e-45 154.9 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 KEG13234.1 - 4.3e-06 26.2 1.4 7.8e-05 22.1 0.2 3.0 2 1 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Tetraspannin PF00335.15 KEG13235.1 - 3.4e-07 29.7 10.6 3.4e-07 29.7 7.3 1.8 2 0 0 2 2 2 1 Tetraspanin family Peptidase_M64 PF09471.5 KEG13235.1 - 3.5e-06 26.8 0.0 7.5e-06 25.7 0.0 1.5 1 1 0 1 1 1 1 IgA Peptidase M64 YWFCY PF14293.1 KEG13235.1 - 2.7 7.8 5.6 3.2 7.6 2.6 2.1 1 1 1 2 2 2 0 YWFCY protein GTP_EFTU PF00009.22 KEG13236.1 - 2.1e-09 37.1 0.0 3.3e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF87 PF01935.12 KEG13236.1 - 0.0015 18.3 0.1 0.0026 17.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF87 ABC_tran PF00005.22 KEG13236.1 - 0.0037 17.5 0.0 0.0082 16.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter MobB PF03205.9 KEG13236.1 - 0.0091 15.7 0.2 0.024 14.3 0.1 1.7 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 KEG13236.1 - 0.012 15.1 0.1 0.028 13.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 KEG13236.1 - 0.021 13.9 0.1 0.048 12.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 KEG13236.1 - 0.036 13.4 0.2 9 5.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.1 KEG13236.1 - 0.045 13.3 0.0 0.26 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KEG13236.1 - 0.046 13.8 0.0 0.079 13.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.1 KEG13236.1 - 0.069 13.1 0.4 0.22 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.7 KEG13236.1 - 0.075 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.1 KEG13236.1 - 0.087 12.7 0.6 0.21 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KEG13236.1 - 0.087 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain MMR_HSR1 PF01926.18 KEG13236.1 - 0.14 12.0 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KEG13236.1 - 0.17 11.4 0.3 2.3 7.7 0.1 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 KEG13236.1 - 0.17 12.7 0.0 0.43 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain V-SNARE PF05008.10 KEG13237.1 - 0.0018 18.3 4.0 0.0018 18.3 2.7 2.2 1 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus WD40 PF00400.27 KEG13237.1 - 0.036 13.9 4.3 9 6.3 0.0 4.3 4 0 0 4 4 4 0 WD domain, G-beta repeat GAS PF13851.1 KEG13237.1 - 1.6 7.8 9.3 0.76 8.9 4.7 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Ribosomal_L35Ae PF01247.13 KEG13238.1 - 9.2e-36 121.5 2.2 1.4e-35 120.9 1.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 KEG13238.1 - 3.9e-05 23.5 1.0 0.1 12.5 0.0 2.3 2 1 0 2 2 2 2 RimM N-terminal domain DUF4364 PF14277.1 KEG13238.1 - 0.0059 16.2 0.1 0.0082 15.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) DUF2910 PF11139.3 KEG13239.1 - 0.036 13.1 0.0 0.04 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2910) Tropomyosin_1 PF12718.2 KEG13242.1 - 0.0092 15.8 2.2 0.0092 15.8 1.5 8.4 4 2 4 8 8 8 2 Tropomyosin like MtrG PF04210.8 KEG13242.1 - 0.24 11.0 7.4 2 8.1 0.5 3.5 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G Reo_sigmaC PF04582.7 KEG13242.1 - 2.5 7.1 34.9 5.1 6.1 2.6 6.2 3 2 2 6 6 6 0 Reovirus sigma C capsid protein LRR_6 PF13516.1 KEG13243.1 - 3.4e-07 29.6 4.9 0.14 12.3 0.1 4.2 3 1 0 3 3 3 3 Leucine Rich repeat LRR_7 PF13504.1 KEG13243.1 - 0.21 11.9 7.3 11 6.7 0.1 4.2 3 2 1 4 4 4 0 Leucine rich repeat LRR_4 PF12799.2 KEG13243.1 - 0.3 10.7 5.2 12 5.6 2.4 3.4 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEG13243.1 - 0.56 10.4 11.8 1.5 9.1 0.1 4.2 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.1 KEG13243.1 - 1.6 8.5 4.2 10 5.9 1.8 2.8 2 1 0 2 2 2 0 Leucine rich repeat WD40 PF00400.27 KEG13244.1 - 4.4e-07 29.5 3.7 0.19 11.6 0.0 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat BBS2_N PF14781.1 KEG13244.1 - 0.059 13.0 0.1 4.4 6.9 0.0 3.6 5 0 0 5 5 5 0 Ciliary BBSome complex subunit 2, N-terminal Phostensin_N PF13916.1 KEG13244.1 - 0.15 12.1 0.0 1.6 8.7 0.0 2.2 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal Rad60-SLD PF11976.3 KEG13245.1 - 0.0019 17.8 0.1 0.0032 17.1 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KEG13245.1 - 0.027 13.8 0.2 0.049 13.0 0.1 1.5 1 1 0 1 1 1 0 Ubiquitin family BRO1 PF03097.13 KEG13247.1 - 1.2e-20 73.6 0.1 1.6e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 BRO1-like domain TFIID_90kDa PF04494.10 KEG13247.1 - 0.012 15.6 0.1 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit CoA_binding PF02629.14 KEG13248.1 - 2e-26 92.2 3.1 2.7e-26 91.9 1.1 2.0 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 KEG13248.1 - 8.1e-22 77.4 2.4 9.5e-22 77.2 0.2 1.9 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.1 KEG13248.1 - 2.2e-06 27.3 0.0 4.9e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 KEG13248.1 - 8.2e-05 22.7 0.1 0.00029 20.9 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain eIF3_subunit PF08597.5 KEG13249.1 - 2.4e-10 40.4 21.1 3.1e-10 40.0 14.6 1.2 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF3474 PF11960.3 KEG13249.1 - 0.63 10.0 3.9 4.1 7.4 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3474) KBP_C PF12309.3 KEG13250.1 - 9.7e-99 330.8 0.5 3.3e-98 329.0 0.1 1.9 2 0 0 2 2 2 1 KIF-1 binding protein C terminal DUF626 PF04776.7 KEG13250.1 - 0.06 13.6 0.7 16 5.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF626) TPR_12 PF13424.1 KEG13250.1 - 0.37 10.7 8.3 0.85 9.6 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat SNARE PF05739.14 KEG13251.1 - 3e-05 23.6 1.1 3e-05 23.6 0.8 2.8 5 0 0 5 5 5 1 SNARE domain Snapin_Pallidin PF14712.1 KEG13251.1 - 0.00017 21.8 0.5 0.00017 21.8 0.3 2.4 3 1 0 3 3 3 1 Snapin/Pallidin Allexi_40kDa PF05549.6 KEG13251.1 - 0.005 16.1 0.4 1.1 8.4 0.1 2.1 2 0 0 2 2 2 2 Allexivirus 40kDa protein Syntaxin-6_N PF09177.6 KEG13251.1 - 0.019 15.3 1.3 0.22 11.9 0.1 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal V-SNARE_C PF12352.3 KEG13251.1 - 0.019 15.0 1.2 0.03 14.3 0.2 1.9 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus TrbL PF04610.9 KEG13251.1 - 0.066 12.8 0.1 5.2 6.6 0.0 2.1 2 0 0 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein Erf4 PF10256.4 KEG13251.1 - 0.12 12.2 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family MtrG PF04210.8 KEG13251.1 - 0.17 11.5 1.2 0.57 9.8 0.7 2.0 1 1 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G CCDC-167 PF15188.1 KEG13251.1 - 0.35 10.8 2.5 0.39 10.6 0.0 2.3 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 Laminin_II PF06009.7 KEG13251.1 - 1.3 8.7 5.2 1.5 8.5 0.2 2.4 2 1 0 2 2 2 0 Laminin Domain II Spc7 PF08317.6 KEG13251.1 - 1.8 7.1 6.3 0.84 8.2 0.9 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein TPR_11 PF13414.1 KEG13252.1 - 3.7e-25 87.3 29.7 1.2e-10 40.8 2.9 4.4 2 2 2 4 4 4 4 TPR repeat TPR_2 PF07719.12 KEG13252.1 - 4e-21 73.1 17.8 2.8e-06 26.8 0.0 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.23 KEG13252.1 - 1.3e-20 72.0 13.6 1.5e-05 24.3 0.0 6.7 6 1 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 KEG13252.1 - 1.1e-14 54.1 16.9 5.5e-05 23.0 0.5 4.6 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 KEG13252.1 - 3.6e-13 48.2 1.5 0.022 14.4 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 KEG13252.1 - 6.2e-12 45.0 14.8 0.033 14.8 0.0 6.2 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.1 KEG13252.1 - 1.4e-09 38.1 8.1 3.1e-05 24.2 0.8 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEG13252.1 - 1.4e-08 35.1 17.7 0.00054 20.5 4.5 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 KEG13252.1 - 1.1e-05 25.2 7.4 0.35 11.1 0.1 5.4 8 0 0 8 8 6 2 Tetratricopeptide repeat Apc3 PF12895.2 KEG13252.1 - 0.0014 18.6 13.4 0.014 15.5 1.6 3.0 3 0 0 3 3 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KEG13252.1 - 0.0029 17.4 15.2 0.037 13.8 2.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEG13252.1 - 0.011 15.4 15.6 0.37 10.6 0.2 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.1 KEG13252.1 - 0.013 15.6 8.4 0.17 11.9 0.5 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat Adeno_VII PF03228.9 KEG13252.1 - 0.032 14.8 1.0 0.032 14.8 0.7 2.5 2 1 0 2 2 2 0 Adenoviral core protein VII TPR_10 PF13374.1 KEG13252.1 - 0.11 12.5 18.3 0.6 10.1 0.5 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEG13252.1 - 0.12 12.8 9.0 6.7 7.4 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat mRNA_triPase PF02940.10 KEG13253.1 - 1.1e-23 84.1 0.0 1.4e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain GTP_EFTU PF00009.22 KEG13255.1 - 3.9e-46 156.8 0.0 6.1e-46 156.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 KEG13255.1 - 5.7e-17 61.3 0.0 1.3e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.13 KEG13255.1 - 6.8e-08 32.0 0.0 2.1e-07 30.5 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.20 KEG13255.1 - 3.7e-05 23.7 0.0 8.4e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KEG13255.1 - 0.002 17.9 0.0 0.0045 16.7 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.5 KEG13255.1 - 0.069 12.3 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Rieske_2 PF13806.1 KEG13256.1 - 8.1e-09 35.1 0.0 1.5e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.21 KEG13256.1 - 2.5e-08 33.3 0.5 5.3e-08 32.3 0.2 1.6 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain NAD_binding_6 PF08030.7 KEG13256.1 - 0.0064 16.4 0.0 0.58 10.0 0.0 2.2 1 1 1 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.19 KEG13256.1 - 0.022 14.8 0.0 0.052 13.6 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain SpoIIE PF07228.7 KEG13257.1 - 2.6e-12 46.8 0.1 2.4e-11 43.7 0.1 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 KEG13257.1 - 3e-06 26.7 0.1 6.3e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 KEG13257.1 - 2.3e-05 23.9 0.0 0.00019 20.9 0.0 2.3 3 0 0 3 3 3 1 Protein phosphatase 2C SNF2_N PF00176.18 KEG13258.1 - 1.2e-45 155.6 0.0 1.8e-45 155.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEG13258.1 - 2.6e-13 49.6 0.0 6.8e-13 48.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PHD PF00628.24 KEG13258.1 - 4.9e-06 26.1 14.4 0.00013 21.5 1.6 3.2 3 0 0 3 3 3 2 PHD-finger C1_1 PF00130.17 KEG13258.1 - 0.0034 17.0 1.2 0.0034 17.0 0.8 3.0 3 0 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 KEG13258.1 - 0.019 14.2 0.7 0.019 14.2 0.5 3.0 2 0 0 2 2 2 0 PHD-finger zf-PHD-like PF15446.1 KEG13258.1 - 0.17 11.1 7.9 0.34 10.1 0.8 2.6 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PseudoU_synth_2 PF00849.17 KEG13259.1 - 3.8e-24 85.3 0.7 1.2e-23 83.7 0.5 1.9 1 1 0 1 1 1 1 RNA pseudouridylate synthase NIF PF03031.13 KEG13261.1 - 4.7e-46 156.3 0.1 7e-46 155.7 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase AAA_16 PF13191.1 KEG13262.1 - 6e-06 26.3 0.3 1e-05 25.5 0.2 1.4 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.10 KEG13262.1 - 0.00062 18.5 0.0 0.0013 17.5 0.0 1.4 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_30 PF13604.1 KEG13262.1 - 0.0018 17.8 3.0 0.0069 15.9 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 KEG13262.1 - 0.0074 17.0 0.1 0.041 14.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KEG13262.1 - 0.011 16.0 0.1 0.038 14.2 0.1 2.1 1 1 0 1 1 1 0 AAA domain CPT PF07931.7 KEG13262.1 - 0.02 14.5 0.5 5.7 6.5 0.2 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_26 PF13500.1 KEG13262.1 - 0.036 13.6 0.7 8.1 5.9 0.0 2.7 2 1 1 3 3 3 0 AAA domain AAA_22 PF13401.1 KEG13262.1 - 0.038 14.1 0.1 0.093 12.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 KEG13262.1 - 0.053 12.9 4.2 0.073 12.5 0.5 2.4 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.7 KEG13262.1 - 0.077 12.0 0.0 0.32 10.0 0.0 1.9 1 1 0 1 1 1 0 Zeta toxin Ras_bdg_2 PF14847.1 KEG13262.1 - 0.08 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Ras-binding domain of Byr2 PORR PF11955.3 KEG13263.1 - 0.0062 15.3 0.2 0.63 8.7 0.0 2.1 2 0 0 2 2 2 2 Plant organelle RNA recognition domain Transket_pyr PF02779.19 KEG13265.1 - 9.5e-49 165.2 0.0 1.2e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KEG13265.1 - 4.1e-38 130.1 0.0 1.1e-37 128.7 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain DUF460 PF04312.8 KEG13265.1 - 0.09 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF460) LSM PF01423.17 KEG13266.1 - 5e-13 48.3 0.1 6.6e-13 47.9 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KEG13266.1 - 0.0016 18.3 0.3 0.0036 17.1 0.2 1.6 1 1 0 1 1 1 1 Ataxin 2 SM domain LRR_4 PF12799.2 KEG13267.1 - 5.3e-12 45.0 8.6 1.6e-06 27.5 0.3 3.6 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 KEG13267.1 - 4.5e-11 42.6 0.6 2.5e-10 40.1 0.0 2.2 2 0 0 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.1 KEG13267.1 - 6.1e-08 32.3 10.5 9e-07 28.5 2.7 2.5 2 0 0 2 2 2 2 Leucine rich repeat DUF4570 PF15134.1 KEG13267.1 - 0.0037 17.0 7.0 0.0037 17.0 4.9 4.1 5 0 0 5 5 5 1 Domain of unknown function (DUF4570) LRR_1 PF00560.28 KEG13267.1 - 0.0048 16.7 14.7 0.29 11.2 0.1 5.0 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 KEG13267.1 - 0.019 15.0 10.5 7.1 7.3 0.0 4.9 4 0 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.1 KEG13267.1 - 0.46 10.6 5.0 6.2 7.2 0.0 3.9 3 1 0 3 3 3 0 Leucine Rich repeat Flg_hook PF02120.11 KEG13268.1 - 0.066 12.8 0.1 0.081 12.6 0.1 1.2 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK DnaJ PF00226.26 KEG13269.1 - 3.4e-07 29.9 0.2 3.5e-06 26.6 0.1 2.1 1 1 0 1 1 1 1 DnaJ domain HSCB_C PF07743.8 KEG13269.1 - 6.7e-07 29.6 0.8 1.6e-06 28.4 0.0 2.1 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain TmoB PF06234.7 KEG13269.1 - 0.069 13.0 0.2 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Toluene-4-monooxygenase system protein B (TmoB) HORMA PF02301.13 KEG13270.1 - 3.2e-38 131.2 0.0 3.7e-38 131.0 0.0 1.0 1 0 0 1 1 1 1 HORMA domain ATG13 PF10033.4 KEG13270.1 - 0.017 14.5 0.1 0.28 10.5 0.0 2.0 2 0 0 2 2 2 0 Autophagy-related protein 13 SBP_bac_3 PF00497.15 KEG13270.1 - 0.075 12.2 0.1 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 DUF1649 PF07855.7 KEG13270.1 - 0.092 12.4 0.2 1.1 8.9 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1649) EFP_N PF08207.7 KEG13272.1 - 8e-05 22.4 0.2 0.00012 21.8 0.2 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain DUF3290 PF11694.3 KEG13272.1 - 0.082 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) COX6B PF02297.12 KEG13273.1 - 0.0092 15.9 0.7 0.015 15.2 0.5 1.4 1 1 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.8 KEG13273.1 - 0.027 14.4 2.1 0.42 10.5 0.1 2.2 2 0 0 2 2 2 0 CHCH domain DAGAT PF03982.8 KEG13274.1 - 1.5e-81 273.3 0.0 2e-81 272.9 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase RSV_NS2 PF03113.9 KEG13274.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Respiratory synctial virus non-structural protein NS2 JAB PF01398.16 KEG13276.1 - 2.9e-06 27.0 0.0 9.5e-06 25.3 0.0 1.9 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UPF0172 PF03665.8 KEG13276.1 - 0.0077 15.7 0.7 0.025 14.0 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0172) WD40 PF00400.27 KEG13277.1 - 6.4e-17 60.7 8.1 0.0088 15.9 0.1 9.4 11 0 0 11 11 11 5 WD domain, G-beta repeat BRCT PF00533.21 KEG13278.1 - 2e-13 50.2 0.0 0.0002 21.4 0.0 4.4 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KEG13278.1 - 8.8e-05 22.2 0.3 0.0042 16.9 0.0 3.5 4 0 0 4 4 4 1 twin BRCT domain NIF PF03031.13 KEG13281.1 - 1.1e-16 60.9 0.0 2e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase RNase_H2-Ydr279 PF09468.5 KEG13281.1 - 0.46 9.6 6.2 0.79 8.8 0.1 2.2 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) Ctr PF04145.10 KEG13281.1 - 1.2 9.1 5.1 31 4.5 0.0 3.0 3 0 0 3 3 3 0 Ctr copper transporter family U79_P34 PF03064.11 KEG13281.1 - 3.6 7.0 19.3 1.8 8.0 8.0 2.3 2 0 0 2 2 2 0 HSV U79 / HCMV P34 Sporozoite_P67 PF05642.6 KEG13282.1 - 0.027 12.3 0.1 0.035 11.9 0.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Herpes_capsid PF06112.6 KEG13282.1 - 0.11 12.5 2.5 0.4 10.7 1.7 1.9 1 1 0 1 1 1 0 Gammaherpesvirus capsid protein DUF3439 PF11921.3 KEG13282.1 - 3.6 7.3 10.0 8.5 6.1 6.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Rieske PF00355.21 KEG13284.1 - 7e-16 57.5 0.0 1.2e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain SK_channel PF03530.9 KEG13284.1 - 0.11 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Calcium-activated SK potassium channel PIN_4 PF13638.1 KEG13285.1 - 0.11 12.5 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 PIN domain DnaJ PF00226.26 KEG13286.1 - 8.4e-21 73.4 0.5 1.4e-20 72.7 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain Methyltransf_23 PF13489.1 KEG13288.1 - 2.5e-14 53.3 0.0 4e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEG13288.1 - 1.4e-11 44.6 0.0 3.1e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEG13288.1 - 6.3e-09 35.2 0.0 9.9e-09 34.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KEG13288.1 - 7.2e-07 29.6 0.0 2e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEG13288.1 - 1.4e-06 27.9 0.0 2.7e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEG13288.1 - 0.00016 21.6 0.0 0.0013 18.7 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEG13288.1 - 0.00069 19.9 0.0 0.0016 18.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEG13288.1 - 0.027 15.0 0.0 0.061 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KEG13288.1 - 0.078 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain AsnC_trans_reg PF01037.16 KEG13288.1 - 0.12 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 AsnC family Peptidase_C14 PF00656.17 KEG13289.1 - 3.2e-58 197.3 0.0 4.1e-58 196.9 0.0 1.1 1 0 0 1 1 1 1 Caspase domain TMF_TATA_bd PF12325.3 KEG13290.1 - 0.0002 21.0 1.6 0.0028 17.3 1.6 2.5 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding IncA PF04156.9 KEG13290.1 - 0.016 14.8 0.5 0.038 13.5 0.0 1.9 2 0 0 2 2 2 0 IncA protein DUF3085 PF11284.3 KEG13290.1 - 0.039 14.1 0.0 1.1 9.4 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3085) DnaJ PF00226.26 KEG13293.1 - 0.03 14.0 0.0 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 DnaJ domain PhoD PF09423.5 KEG13294.1 - 1.1e-15 57.1 0.0 1.7e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase DUF4633 PF15464.1 KEG13295.1 - 0.027 14.2 0.1 0.086 12.6 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4633) AF-4 PF05110.8 KEG13296.1 - 1.4 6.7 10.9 1.8 6.2 7.5 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein UBN2 PF14223.1 KEG13297.1 - 0.00018 21.2 9.9 0.009 15.7 3.6 3.9 3 1 0 3 3 3 1 gag-polypeptide of LTR copia-type NAD_binding_5 PF07994.7 KEG13297.1 - 0.04 13.4 0.2 0.094 12.1 0.2 1.6 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase DUF2959 PF11172.3 KEG13297.1 - 0.37 10.5 11.9 0.044 13.5 3.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2959) V_ATPase_I PF01496.14 KEG13297.1 - 1.1 7.0 7.9 0.25 9.1 1.2 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Robl_LC7 PF03259.12 KEG13298.1 - 3.8e-21 74.4 0.0 4.3e-21 74.2 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain Mito_carr PF00153.22 KEG13299.1 - 5.3e-27 93.3 6.0 2.3e-13 49.6 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein UDPGP PF01704.13 KEG13300.1 - 2.1e-93 313.1 0.0 2.7e-93 312.7 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase TcdB_N PF12918.2 KEG13301.1 - 0.0037 17.2 0.1 0.013 15.6 0.1 1.9 1 0 0 1 1 1 1 TcdB toxin N-terminal helical domain DUF1042 PF06294.6 KEG13301.1 - 0.072 12.6 2.6 0.038 13.5 0.5 1.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1042) Seryl_tRNA_N PF02403.17 KEG13301.1 - 6 6.9 13.2 29 4.7 7.3 2.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain IQ PF00612.22 KEG13302.1 - 0.0035 16.8 9.9 2.1 8.2 6.0 3.0 2 0 0 2 2 2 2 IQ calmodulin-binding motif DUF1033 PF06279.6 KEG13302.1 - 0.44 10.3 2.4 1.3 8.8 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1033) Mannosyl_trans2 PF04188.8 KEG13303.1 - 2.9e-35 122.0 20.0 1.6e-26 93.2 11.1 2.4 2 0 0 2 2 2 2 Mannosyltransferase (PIG-V)) DUF563 PF04577.9 KEG13304.1 - 2.3e-21 76.6 0.0 3.7e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) CpXC PF14353.1 KEG13305.1 - 0.18 11.7 1.5 0.28 11.1 0.1 2.0 1 1 0 1 1 1 0 CpXC protein Nrap PF03813.9 KEG13306.1 - 9.2e-62 208.8 0.0 9.6e-61 205.5 0.0 1.9 1 1 0 1 1 1 1 Nrap protein Mem_trans PF03547.13 KEG13306.1 - 0.15 10.2 0.0 0.29 9.3 0.0 1.4 1 0 0 1 1 1 0 Membrane transport protein DUF327 PF03885.8 KEG13308.1 - 0.17 11.6 0.4 0.35 10.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF327) EF-hand_8 PF13833.1 KEG13309.1 - 0.059 12.9 0.1 2.1 8.0 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair Chorein_N PF12624.2 KEG13310.1 - 1.2e-23 82.8 0.3 2.3e-10 40.0 0.2 2.7 2 0 0 2 2 2 2 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF563 PF04577.9 KEG13312.1 - 1.1e-14 54.9 0.6 2.6e-14 53.6 0.1 1.8 1 1 0 2 2 2 1 Protein of unknown function (DUF563) EF1_GNE PF00736.14 KEG13313.1 - 7.8e-28 96.0 0.3 1.4e-27 95.1 0.2 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain Sorting_nexin PF03700.8 KEG13313.1 - 0.028 14.5 9.7 0.88 9.6 1.3 2.5 1 1 1 2 2 2 0 Sorting nexin, N-terminal domain DUF3140 PF11338.3 KEG13313.1 - 0.2 11.8 1.9 0.38 10.9 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) Pilt PF15453.1 KEG13313.1 - 0.24 11.0 2.1 0.32 10.6 1.4 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions ACC_epsilon PF13822.1 KEG13313.1 - 0.67 10.3 7.4 10 6.5 0.6 2.7 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit Metallophos PF00149.23 KEG13314.1 - 2e-32 112.2 0.1 2.5e-32 111.9 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_L13 PF00572.13 KEG13315.1 - 6.2e-20 71.5 1.2 8.3e-20 71.1 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L13 alpha-hel2 PF14456.1 KEG13315.1 - 0.17 10.5 1.3 0.26 10.0 0.9 1.2 1 0 0 1 1 1 0 Alpha-helical domain 2 Amastin PF07344.6 KEG13318.1 - 1.1e-07 31.5 3.4 1.6e-07 31.1 2.4 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein SUR7 PF06687.7 KEG13318.1 - 0.12 11.9 0.2 0.12 11.9 0.1 2.2 3 0 0 3 3 3 0 SUR7/PalI family HIG_1_N PF04588.8 KEG13318.1 - 1.2 8.8 7.5 4.6 7.0 0.2 2.9 3 1 0 3 3 3 0 Hypoxia induced protein conserved region Methyltransf_15 PF09445.5 KEG13319.1 - 8.1e-31 106.7 0.1 1e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 KEG13319.1 - 7.4e-12 45.3 0.0 1.1e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEG13319.1 - 8.7e-11 41.6 0.0 1.1e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEG13319.1 - 9.7e-11 41.9 0.1 1.6e-10 41.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 KEG13319.1 - 3.4e-10 39.7 0.0 4.9e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.2 KEG13319.1 - 2.4e-09 37.7 0.1 3.3e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEG13319.1 - 7.9e-09 35.1 0.0 1.1e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain tRNA_U5-meth_tr PF05958.6 KEG13319.1 - 4.2e-06 25.6 0.0 5.8e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Met_10 PF02475.11 KEG13319.1 - 2.2e-05 24.1 0.0 2.5e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.10 KEG13319.1 - 4.5e-05 22.9 0.0 6.1e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.7 KEG13319.1 - 0.00017 22.0 0.2 0.00036 20.9 0.1 1.5 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.8 KEG13319.1 - 0.0013 17.9 0.1 0.0018 17.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 KEG13319.1 - 0.0022 17.5 0.0 0.0032 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.4 KEG13319.1 - 0.003 17.0 0.0 0.0058 16.1 0.0 1.4 2 0 0 2 2 1 1 Putative methyltransferase DNA_methylase PF00145.12 KEG13319.1 - 0.004 16.3 0.0 0.006 15.7 0.0 1.2 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase RrnaAD PF00398.15 KEG13319.1 - 0.0054 15.7 0.0 0.0072 15.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase TehB PF03848.9 KEG13319.1 - 0.0089 15.2 0.2 0.013 14.7 0.1 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Ubie_methyltran PF01209.13 KEG13319.1 - 0.0099 15.0 0.3 0.018 14.1 0.2 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 KEG13319.1 - 0.015 14.3 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_3 PF01596.12 KEG13319.1 - 0.029 13.4 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_5 PF01795.14 KEG13319.1 - 0.035 13.3 0.0 0.049 12.9 0.0 1.1 1 0 0 1 1 1 0 MraW methylase family NodS PF05401.6 KEG13319.1 - 0.049 13.0 0.1 0.069 12.5 0.1 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) TPMT PF05724.6 KEG13319.1 - 0.056 12.8 0.1 0.095 12.1 0.1 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Pox_MCEL PF03291.11 KEG13319.1 - 0.094 11.5 0.1 0.12 11.1 0.1 1.1 1 0 0 1 1 1 0 mRNA capping enzyme Methyltransf_26 PF13659.1 KEG13320.1 - 6.1e-05 23.0 0.0 0.00022 21.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEG13320.1 - 0.025 14.1 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KEG13320.1 - 0.036 14.6 0.3 0.2 12.2 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain Topo_C_assoc PF14370.1 KEG13321.1 - 0.058 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 C-terminal topoisomerase domain AAA_22 PF13401.1 KEG13322.1 - 1.9e-07 31.2 0.0 4.3e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KEG13322.1 - 1.1e-06 28.9 0.0 4.8e-06 26.8 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KEG13322.1 - 0.0061 16.2 0.0 0.019 14.6 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 KEG13322.1 - 0.011 15.3 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 KEG13322.1 - 0.011 15.6 0.0 0.033 14.1 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain DUF2075 PF09848.4 KEG13322.1 - 0.13 11.1 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PPR PF01535.15 KEG13323.1 - 5.2e-12 44.8 1.1 0.00087 19.1 0.0 5.9 6 0 0 6 6 6 3 PPR repeat PPR_2 PF13041.1 KEG13323.1 - 8.4e-09 35.2 0.2 0.031 14.2 0.0 4.9 3 1 2 5 5 5 3 PPR repeat family PPR_1 PF12854.2 KEG13323.1 - 2.6e-06 26.7 0.0 0.035 13.5 0.0 3.4 3 0 0 3 3 3 2 PPR repeat PPR_3 PF13812.1 KEG13323.1 - 9.8e-05 22.3 0.3 20 5.7 0.0 5.9 6 0 0 6 6 6 1 Pentatricopeptide repeat domain Beach PF02138.13 KEG13324.1 - 4.6e-93 311.5 0.0 6.3e-93 311.1 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 KEG13324.1 - 3.7e-10 39.5 0.0 1.4e-09 37.7 0.0 2.0 1 1 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 KEG13324.1 - 3.1e-06 26.8 3.4 0.0015 18.3 0.1 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat zf-DHHC PF01529.15 KEG13325.1 - 6.6e-33 113.5 9.0 6.6e-33 113.5 6.2 1.3 1 1 0 1 1 1 1 DHHC palmitoyltransferase DUF3040 PF11239.3 KEG13325.1 - 2.8 8.0 4.6 0.69 10.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) NYD-SP28 PF14772.1 KEG13326.1 - 1.9e-08 34.3 10.3 1.9e-08 34.3 7.1 5.0 2 1 3 5 5 5 1 Sperm tail NYD-SP28_assoc PF14775.1 KEG13326.1 - 6.8e-07 28.8 3.1 6.8e-07 28.8 2.1 2.9 3 0 0 3 3 3 1 Sperm tail C-terminal domain NFRKB_winged PF14465.1 KEG13326.1 - 0.22 11.3 7.5 5.8 6.8 0.1 3.3 2 1 1 3 3 3 0 NFRKB Winged Helix-like UPF0164 PF03687.8 KEG13328.1 - 0.14 10.6 0.0 3 6.2 0.0 2.2 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0164) Ank_2 PF12796.2 KEG13329.1 - 6e-08 32.9 1.1 0.00015 22.0 1.2 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) IQ PF00612.22 KEG13329.1 - 4.2e-07 29.0 14.1 0.00011 21.5 1.4 3.1 2 0 0 2 2 2 2 IQ calmodulin-binding motif Ank_4 PF13637.1 KEG13329.1 - 1.3e-06 28.7 0.6 0.0037 17.7 0.2 3.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEG13329.1 - 0.0001 22.2 1.2 4.8 7.7 0.0 5.3 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.1 KEG13329.1 - 0.012 15.8 6.8 3.9 7.8 0.1 4.3 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Ank PF00023.25 KEG13329.1 - 0.65 9.9 9.4 3.2 7.7 0.0 4.9 6 0 0 6 6 6 0 Ankyrin repeat IQ PF00612.22 KEG13330.1 - 0.0044 16.5 0.1 0.02 14.5 0.0 2.3 2 0 0 2 2 2 1 IQ calmodulin-binding motif Guanylate_cyc PF00211.15 KEG13331.1 - 8.6e-14 51.3 0.0 2.6e-13 49.7 0.0 1.7 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Globin PF00042.17 KEG13331.1 - 1.7e-12 47.6 0.1 2.8e-06 27.6 0.0 3.0 2 1 0 2 2 2 2 Globin DUF3500 PF12006.3 KEG13331.1 - 0.061 12.2 0.0 0.099 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3500) PLAC8 PF04749.12 KEG13332.1 - 0.00028 21.3 32.8 0.0048 17.4 22.8 2.6 1 1 0 1 1 1 1 PLAC8 family DUF747 PF05346.6 KEG13333.1 - 5.4e-74 249.2 4.4 7.3e-74 248.7 3.1 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family FH2 PF02181.18 KEG13334.1 - 4e-61 206.9 2.2 3.6e-60 203.8 0.1 2.1 2 0 0 2 2 2 1 Formin Homology 2 Domain V-SNARE PF05008.10 KEG13334.1 - 0.039 14.1 0.7 0.039 14.1 0.5 3.6 5 0 0 5 5 5 0 Vesicle transport v-SNARE protein N-terminus THOC7 PF05615.8 KEG13334.1 - 1 9.6 5.8 5.7 7.2 0.7 3.2 3 0 0 3 3 3 0 Tho complex subunit 7 IATP PF04568.7 KEG13334.1 - 4.1 7.4 8.1 0.46 10.5 2.2 1.9 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP DUF1751 PF08551.5 KEG13335.1 - 0.00015 22.0 5.8 0.00039 20.6 4.0 1.7 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) DUF1129 PF06570.6 KEG13335.1 - 0.25 10.6 2.8 0.83 8.9 2.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) Rhomboid PF01694.17 KEG13335.1 - 1.1 9.2 12.3 0.15 12.1 4.9 2.2 2 1 0 2 2 2 0 Rhomboid family tRNA_Me_trans PF03054.11 KEG13337.1 - 1.5e-47 161.8 0.0 2.3e-37 128.3 0.0 3.3 2 2 1 3 3 3 3 tRNA methyl transferase Asn_synthase PF00733.16 KEG13337.1 - 0.0019 17.7 0.0 0.0035 16.8 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase Sec7 PF01369.15 KEG13338.1 - 9.1e-38 129.8 0.0 1.7e-37 128.9 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain EF-hand_8 PF13833.1 KEG13339.1 - 1.2e-23 82.4 4.2 2.3e-08 33.5 0.0 4.6 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_7 PF13499.1 KEG13339.1 - 7.2e-22 77.3 0.4 3.2e-06 27.1 0.0 4.2 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.27 KEG13339.1 - 1.5e-21 73.9 7.2 3.1e-06 26.1 0.3 5.4 6 0 0 6 6 6 4 EF hand EF-hand_6 PF13405.1 KEG13339.1 - 2.7e-20 70.3 5.0 0.00022 20.8 0.0 5.3 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 KEG13339.1 - 5.4e-11 41.3 5.3 0.0035 16.6 0.2 4.4 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 KEG13339.1 - 0.0049 16.7 0.8 7.3 6.5 0.0 4.7 6 0 0 6 6 6 1 EF-hand domain SPARC_Ca_bdg PF10591.4 KEG13339.1 - 0.0075 16.2 0.0 0.061 13.3 0.0 2.5 3 0 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KEG13339.1 - 0.054 13.2 0.0 1.2 8.9 0.0 2.5 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_like PF09279.6 KEG13339.1 - 0.24 11.4 0.9 4.5 7.3 0.0 3.3 5 0 0 5 5 5 0 Phosphoinositide-specific phospholipase C, efhand-like Peptidase_M16_C PF05193.16 KEG13340.1 - 1.7e-29 102.8 0.1 1.5e-18 67.1 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain M16C_assoc PF08367.6 KEG13340.1 - 6.2e-24 84.1 0.0 1.3e-23 83.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16 PF00675.15 KEG13340.1 - 1.2e-11 44.5 0.2 2.8e-10 40.1 0.0 3.0 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) FAP PF07174.6 KEG13341.1 - 0.26 10.5 6.6 0.48 9.6 4.6 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Herpes_BTRF1 PF04682.7 KEG13342.1 - 0.0008 18.8 0.0 0.0012 18.1 0.0 1.3 1 0 0 1 1 1 1 Herpesvirus BTRF1 protein conserved region Cytochrom_C1 PF02167.10 KEG13343.1 - 4.5e-62 209.5 0.0 5.5e-62 209.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Adaptin_N PF01602.15 KEG13344.1 - 2.1e-78 263.9 1.7 2.7e-78 263.5 1.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Peptidase_M20 PF01546.23 KEG13346.1 - 2.3e-26 92.4 0.0 3e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KEG13346.1 - 5.9e-19 67.8 0.0 8.7e-19 67.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M42 PF05343.9 KEG13346.1 - 0.019 13.7 0.0 0.071 11.8 0.0 1.8 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase GalKase_gal_bdg PF10509.4 KEG13347.1 - 5.7e-18 63.9 0.0 1.1e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 KEG13347.1 - 1.5e-08 34.6 0.0 3.5e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 KEG13347.1 - 1.1e-05 25.4 0.0 3.7e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 GHMP kinases N terminal domain Ribul_P_3_epim PF00834.14 KEG13348.1 - 4.2e-58 195.7 0.3 5e-58 195.5 0.2 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family PEX11 PF05648.9 KEG13349.1 - 0.027 13.7 0.1 0.068 12.4 0.1 1.7 1 1 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) PEX11 PF05648.9 KEG13350.1 - 3.3e-13 49.4 0.0 1.7e-12 47.1 0.0 1.8 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DSPn PF14671.1 KEG13350.1 - 0.024 14.6 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half zf-C3HC4_3 PF13920.1 KEG13351.1 - 3e-13 49.1 7.4 3e-13 49.1 5.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEG13351.1 - 8.3e-09 35.3 8.1 8.3e-09 35.3 5.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEG13351.1 - 5.1e-05 22.8 7.6 5.1e-05 22.8 5.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEG13351.1 - 7.3e-05 22.4 7.7 7.3e-05 22.4 5.3 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 KEG13351.1 - 0.00017 21.3 7.5 0.00017 21.3 5.2 1.9 2 0 0 2 2 2 1 Ring finger domain Cytochrome_C7 PF14522.1 KEG13351.1 - 0.54 9.9 4.6 0.95 9.1 3.2 1.4 1 0 0 1 1 1 0 Cytochrome c7 zf-RING_4 PF14570.1 KEG13351.1 - 0.74 9.4 12.1 3.8 7.1 5.0 2.8 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain DZR PF12773.2 KEG13351.1 - 1.3 8.9 14.5 0.91 9.3 2.0 2.6 1 1 1 2 2 2 0 Double zinc ribbon zf-C2H2_6 PF13912.1 KEG13351.1 - 1.4 8.9 0.0 1.4 8.9 0.0 3.0 4 0 0 4 4 4 0 C2H2-type zinc finger PEX11 PF05648.9 KEG13352.1 - 6.5e-12 45.1 0.1 9.4e-12 44.6 0.1 1.2 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) NADHdh-2_N PF12155.3 KEG13352.1 - 0.18 12.0 1.2 0.31 11.2 0.1 1.9 2 0 0 2 2 2 0 NADH dehydrogenase subunit 2 N-terminal IKKbetaNEMObind PF12179.3 KEG13354.1 - 0.81 9.5 4.3 1.6 8.6 0.5 3.3 3 0 0 3 3 3 0 I-kappa-kinase-beta NEMO binding domain Cullin PF00888.17 KEG13357.1 - 1.5e-17 63.4 0.0 3e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Cullin family Ribosomal_L18e PF00828.14 KEG13358.1 - 2e-34 118.7 0.6 2.4e-34 118.4 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Ribosomal_L14 PF00238.14 KEG13359.1 - 4.9e-36 123.1 0.0 5.6e-36 122.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Phage_Gp23 PF10669.4 KEG13361.1 - 0.24 11.4 0.1 0.24 11.4 0.1 2.6 3 0 0 3 3 3 0 Protein gp23 (Bacteriophage A118) Spc42p PF11544.3 KEG13361.1 - 4.8 7.1 10.3 0.17 11.8 0.5 3.4 3 2 0 3 3 3 0 Spindle pole body component Spc42p Takusan PF04822.8 KEG13361.1 - 5.7 6.7 14.8 1.1 9.1 0.8 3.5 3 1 0 3 3 3 0 Takusan SET PF00856.23 KEG13362.1 - 0.0039 17.5 0.0 0.11 12.8 0.0 2.2 1 1 0 1 1 1 1 SET domain Proteasome PF00227.21 KEG13363.1 - 9.2e-48 162.0 0.1 1.1e-47 161.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 KEG13363.1 - 8.4e-05 21.7 0.0 8.4e-05 21.7 0.0 1.8 2 0 0 2 2 2 1 Proteasome beta subunits C terminal DUF1375 PF07119.7 KEG13363.1 - 0.087 12.6 0.0 0.21 11.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1375) Ribosomal_S17 PF00366.15 KEG13364.1 - 5.8e-15 55.0 0.5 5.8e-15 55.0 0.4 1.8 2 0 0 2 2 2 1 Ribosomal protein S17 Rubella_E1 PF05748.6 KEG13364.1 - 0.14 10.6 0.0 0.31 9.5 0.0 1.5 2 0 0 2 2 2 0 Rubella membrane glycoprotein E1 Cpn60_TCP1 PF00118.19 KEG13365.1 - 2.6e-150 501.2 0.9 3e-150 501.0 0.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family NDK PF00334.14 KEG13366.1 - 4e-33 114.0 0.0 2.2e-29 101.9 0.0 2.4 2 0 0 2 2 2 2 Nucleoside diphosphate kinase WD40 PF00400.27 KEG13367.1 - 4.9e-39 130.8 20.3 1e-11 44.2 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Sof1 PF04158.9 KEG13367.1 - 3.5e-10 39.7 6.6 6.2e-10 38.9 4.5 1.4 1 0 0 1 1 1 1 Sof1-like domain Nup160 PF11715.3 KEG13367.1 - 0.012 13.7 1.4 1.7 6.7 0.0 3.0 3 1 0 3 3 3 0 Nucleoporin Nup120/160 DUF2191 PF09957.4 KEG13367.1 - 0.024 14.4 0.8 0.047 13.5 0.6 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2191) EF-hand_7 PF13499.1 KEG13368.1 - 8.4e-13 48.2 0.2 1.6e-10 40.9 0.3 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KEG13368.1 - 2.2e-10 39.0 2.5 3.1e-08 32.3 0.0 3.9 3 1 1 4 4 4 1 EF hand EF-hand_8 PF13833.1 KEG13368.1 - 7.9e-10 38.2 1.5 3.5e-05 23.3 0.1 3.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 KEG13368.1 - 1.1e-09 37.3 0.3 9.8e-06 25.0 0.0 3.5 3 1 0 3 3 3 2 EF-hand domain EF-hand_9 PF14658.1 KEG13368.1 - 3.3e-05 23.7 0.1 0.013 15.4 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 KEG13368.1 - 4.2e-05 22.6 0.0 4.2e-05 22.6 0.0 2.8 3 1 1 4 4 4 1 EF hand UPF0154 PF03672.8 KEG13368.1 - 0.0034 16.9 0.0 0.23 11.0 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) Sterol_MT_C PF08498.5 KEG13370.1 - 2.4e-23 81.8 0.7 4.4e-23 80.9 0.2 1.7 2 0 0 2 2 2 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 KEG13370.1 - 4e-15 56.0 0.0 1.6e-14 54.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEG13370.1 - 1.9e-11 43.7 0.0 3.9e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEG13370.1 - 1.7e-09 37.5 0.0 2.9e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KEG13370.1 - 1.6e-07 30.6 0.0 2.6e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 KEG13370.1 - 9.9e-07 28.0 0.0 1.7e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KEG13370.1 - 1.5e-06 28.5 0.1 2.3e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEG13370.1 - 5.1e-06 26.7 0.1 1.9e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEG13370.1 - 6.3e-05 23.5 0.0 0.002 18.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.5 KEG13370.1 - 0.0078 15.7 0.3 0.012 15.2 0.2 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 KEG13370.1 - 0.058 13.4 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KEG13370.1 - 0.063 12.6 0.0 0.63 9.3 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Med3 PF11593.3 KEG13371.1 - 0.097 11.8 0.9 0.17 11.0 0.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF938 PF06080.7 KEG13373.1 - 3.8e-45 153.9 0.0 4.9e-45 153.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_25 PF13649.1 KEG13373.1 - 0.004 17.4 0.0 0.013 15.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEG13373.1 - 0.0043 17.6 0.0 0.013 16.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEG13373.1 - 0.03 14.8 0.0 0.78 10.2 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain DUF4251 PF14059.1 KEG13373.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4251) Aminotran_1_2 PF00155.16 KEG13374.1 - 3.3e-65 220.4 0.0 3.7e-65 220.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KEG13374.1 - 0.00086 18.5 0.0 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 KEG13374.1 - 0.016 13.5 0.0 0.024 12.9 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KEG13374.1 - 0.016 14.2 0.0 0.051 12.6 0.0 1.8 2 1 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_3 PF00202.16 KEG13374.1 - 0.11 11.2 0.0 0.24 10.2 0.0 1.5 1 0 0 1 1 1 0 Aminotransferase class-III adh_short PF00106.20 KEG13375.1 - 3.2e-15 56.4 0.3 5e-14 52.5 0.2 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEG13375.1 - 3.4e-05 23.5 0.1 6.5e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 KEG13375.1 - 0.015 14.4 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.14 KEG13375.1 - 0.063 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 KEG13375.1 - 0.081 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KEG13375.1 - 0.12 11.8 0.1 0.67 9.3 0.1 2.1 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Endonuclease_5 PF04493.9 KEG13376.1 - 3.7e-52 176.6 0.0 5.3e-52 176.1 0.0 1.2 1 0 0 1 1 1 1 Endonuclease V DUF99 PF01949.11 KEG13376.1 - 0.036 13.1 0.0 0.057 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF99 Glucokinase PF02685.11 KEG13377.1 - 4.8e-18 65.0 0.0 1.8e-17 63.1 0.0 1.7 1 1 0 1 1 1 1 Glucokinase Ribosomal_S18 PF01084.15 KEG13378.1 - 0.0026 17.6 0.0 0.005 16.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S18 Herpes_LMP1 PF05297.6 KEG13379.1 - 0.0093 14.9 0.0 0.017 14.0 0.0 1.4 1 0 0 1 1 1 1 Herpesvirus latent membrane protein 1 (LMP1) KAR PF15222.1 KEG13379.1 - 0.039 14.0 0.3 0.098 12.7 0.2 1.7 1 0 0 1 1 1 0 Kidney androgen-regulated DUF1510 PF07423.6 KEG13379.1 - 2.3 7.5 18.0 16 4.7 11.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) TPR_11 PF13414.1 KEG13380.1 - 1.2e-41 140.1 3.8 1.3e-10 40.8 0.0 6.3 4 2 2 6 6 6 6 TPR repeat TPR_2 PF07719.12 KEG13380.1 - 4.2e-35 116.8 1.5 0.00051 19.7 0.0 9.7 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_1 PF00515.23 KEG13380.1 - 3.5e-34 114.9 2.7 2.9e-05 23.4 0.0 8.3 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.1 KEG13380.1 - 1e-23 83.3 0.0 0.00016 22.2 0.0 6.9 3 2 2 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 KEG13380.1 - 1.1e-23 82.9 10.4 1.1e-05 25.2 0.2 5.9 5 1 2 7 7 6 5 Tetratricopeptide repeat TPR_19 PF14559.1 KEG13380.1 - 2.2e-20 72.7 2.9 1.3e-05 25.4 0.0 6.0 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 KEG13380.1 - 2.3e-20 70.7 0.1 0.001 18.6 0.0 8.1 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.1 KEG13380.1 - 3.3e-17 62.0 2.9 0.0001 22.1 0.0 5.6 3 1 3 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 KEG13380.1 - 3.3e-17 61.4 5.3 9.1e-05 22.7 0.0 7.8 4 2 5 9 9 9 3 Tetratricopeptide repeat Apc3 PF12895.2 KEG13380.1 - 5.3e-17 61.7 10.9 8.3e-06 25.8 0.0 4.3 4 1 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KEG13380.1 - 1.9e-15 55.3 0.3 0.0019 17.8 0.0 6.3 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 KEG13380.1 - 2e-13 49.3 7.0 0.0033 17.5 0.0 7.8 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_6 PF13174.1 KEG13380.1 - 1.5e-12 47.0 5.6 0.29 11.6 0.0 8.0 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_15 PF13429.1 KEG13380.1 - 6.4e-06 25.4 0.4 0.045 12.7 0.0 3.9 1 1 4 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 KEG13380.1 - 1.5e-05 24.7 7.0 2.2 8.3 0.0 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_20 PF14561.1 KEG13380.1 - 0.0054 16.8 2.6 25 5.0 0.0 4.7 4 1 0 4 4 4 0 Tetratricopeptide repeat Coatomer_E PF04733.9 KEG13380.1 - 0.0095 15.1 0.2 1.2 8.2 0.0 3.4 2 1 2 4 4 4 1 Coatomer epsilon subunit NARP1 PF12569.3 KEG13380.1 - 0.027 13.2 0.1 3.8 6.1 0.0 3.1 3 1 1 4 4 4 0 NMDA receptor-regulated protein 1 Guanylate_kin PF00625.16 KEG13382.1 - 4.3e-37 127.3 0.0 2.6e-23 82.4 0.0 2.6 2 1 0 2 2 2 2 Guanylate kinase AAA_33 PF13671.1 KEG13382.1 - 2.2e-08 34.0 0.3 6e-07 29.4 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEG13382.1 - 3.6e-07 30.3 0.0 8e-07 29.2 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 KEG13382.1 - 3.2e-06 26.4 0.0 6.2e-06 25.4 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KEG13382.1 - 1.4e-05 25.0 0.0 0.00012 22.0 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KEG13382.1 - 0.00013 22.0 0.0 0.00022 21.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KEG13382.1 - 0.00019 21.7 0.0 0.0015 18.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KEG13382.1 - 0.00021 21.6 0.0 0.00034 20.9 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_17 PF13207.1 KEG13382.1 - 0.00059 20.6 0.1 0.0012 19.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 KEG13382.1 - 0.00064 19.4 0.0 0.0014 18.3 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 KEG13382.1 - 0.00069 19.1 0.0 0.0014 18.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Dynamin_N PF00350.18 KEG13382.1 - 0.0008 19.2 0.0 0.00089 19.1 0.0 1.4 1 1 0 1 1 1 1 Dynamin family RNA_helicase PF00910.17 KEG13382.1 - 0.0012 18.9 0.1 0.005 16.9 0.0 2.0 2 0 0 2 2 2 1 RNA helicase cobW PF02492.14 KEG13382.1 - 0.0014 18.1 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 KEG13382.1 - 0.0019 17.6 0.0 0.0027 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.7 KEG13382.1 - 0.0026 17.4 0.0 0.0053 16.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_28 PF13521.1 KEG13382.1 - 0.0035 17.3 0.1 0.0092 15.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KEG13382.1 - 0.015 14.9 0.0 0.055 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 KEG13382.1 - 0.016 14.9 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_25 PF13481.1 KEG13382.1 - 0.027 13.8 0.0 0.19 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KEG13382.1 - 0.032 14.5 0.7 0.082 13.2 0.5 1.8 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 KEG13382.1 - 0.04 12.9 0.0 0.06 12.3 0.0 1.3 1 0 0 1 1 1 0 Septin NB-ARC PF00931.17 KEG13382.1 - 0.067 12.0 0.1 0.32 9.8 0.0 2.0 1 1 0 1 1 1 0 NB-ARC domain T2SE PF00437.15 KEG13382.1 - 0.083 11.7 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_21 PF13304.1 KEG13382.1 - 0.091 12.7 0.4 0.17 11.8 0.1 1.5 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KEG13382.1 - 0.094 12.6 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KEG13382.1 - 0.14 11.7 0.0 0.27 10.7 0.0 1.5 2 0 0 2 2 1 0 AAA domain TGS PF02824.16 KEG13383.1 - 1.8e-18 66.0 0.0 3.7e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 KEG13383.1 - 5.8e-17 61.7 0.0 1e-16 60.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KEG13383.1 - 7.2e-10 38.3 0.0 3.2e-09 36.2 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KEG13383.1 - 0.00096 18.6 0.1 2 7.8 0.0 3.4 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain ArgK PF03308.11 KEG13383.1 - 0.0027 16.5 0.1 0.0093 14.7 0.0 1.8 2 0 0 2 2 2 1 ArgK protein Dynamin_N PF00350.18 KEG13383.1 - 0.0055 16.5 0.2 0.9 9.3 0.0 2.4 1 1 1 2 2 2 1 Dynamin family Miro PF08477.8 KEG13383.1 - 0.029 14.8 0.1 0.092 13.2 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein AAA_28 PF13521.1 KEG13383.1 - 0.047 13.6 0.1 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arf PF00025.16 KEG13383.1 - 0.069 12.3 0.0 0.16 11.1 0.0 1.6 1 0 0 1 1 1 0 ADP-ribosylation factor family DUF1192 PF06698.6 KEG13383.1 - 1.4 8.7 3.4 13 5.6 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Spc97_Spc98 PF04130.8 KEG13384.1 - 1.9e-15 56.2 0.0 4.1e-15 55.1 0.0 1.6 1 1 0 1 1 1 1 Spc97 / Spc98 family Sec1 PF00995.18 KEG13385.1 - 5.4e-111 371.9 0.0 6.1e-111 371.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family PTCB-BRCT PF12738.2 KEG13386.1 - 3e-05 23.7 0.2 0.00013 21.7 0.0 2.2 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 KEG13386.1 - 0.00021 21.3 0.0 0.00057 19.9 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF1067 PF06362.6 KEG13387.1 - 0.02 15.4 0.2 0.049 14.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1067) DUF4653 PF15546.1 KEG13387.1 - 0.024 13.9 2.3 0.059 12.6 1.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) PAP_assoc PF03828.14 KEG13388.1 - 1.6e-05 24.7 0.2 4.1e-05 23.4 0.1 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase Spore_coat_CotO PF14153.1 KEG13388.1 - 5.1 6.4 31.2 0.4 10.0 0.5 3.7 3 0 0 3 3 3 0 Spore coat protein CotO SurA_N_3 PF13624.1 KEG13389.1 - 0.018 14.9 0.4 0.034 14.1 0.3 1.4 1 0 0 1 1 1 0 SurA N-terminal domain DUF2423 PF10338.4 KEG13389.1 - 0.024 14.6 4.9 0.024 14.6 3.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2423) Arf PF00025.16 KEG13390.1 - 2.8e-65 218.8 0.0 3.2e-65 218.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KEG13390.1 - 4.8e-14 51.9 0.0 5.9e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KEG13390.1 - 2.6e-13 49.4 0.1 4.1e-11 42.2 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 KEG13390.1 - 3.8e-12 45.8 0.0 4.8e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KEG13390.1 - 3.1e-11 42.8 0.0 3.9e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KEG13390.1 - 4.9e-09 36.7 0.0 6.2e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KEG13390.1 - 1.3e-06 28.3 0.0 1.7e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 KEG13390.1 - 0.0046 16.0 0.0 0.0057 15.7 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase NACHT PF05729.7 KEG13390.1 - 0.0077 15.9 0.5 0.031 13.9 0.3 1.9 1 1 0 1 1 1 1 NACHT domain AAA_33 PF13671.1 KEG13390.1 - 0.013 15.3 0.1 0.022 14.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KEG13390.1 - 0.044 13.6 0.1 6.4 6.6 0.0 2.0 1 1 1 2 2 2 0 AAA domain GTP_EFTU PF00009.22 KEG13390.1 - 0.05 13.0 0.0 0.25 10.7 0.0 1.7 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain CENP-M PF11111.3 KEG13390.1 - 0.065 12.4 0.0 6.4 5.9 0.0 2.1 2 0 0 2 2 2 0 Centromere protein M (CENP-M) APS_kinase PF01583.15 KEG13390.1 - 0.15 11.7 0.1 0.26 10.9 0.1 1.6 1 1 0 1 1 1 0 Adenylylsulphate kinase Ribosomal_L5_C PF00673.16 KEG13391.1 - 3e-22 78.1 0.0 6e-22 77.1 0.0 1.5 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 KEG13391.1 - 4.9e-16 58.2 0.3 2e-15 56.3 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L5 N_Asn_amidohyd PF14736.1 KEG13393.1 - 0.018 13.9 0.1 0.057 12.2 0.0 1.8 2 0 0 2 2 2 0 Protein N-terminal asparagine amidohydrolase Lyase_1 PF00206.15 KEG13394.1 - 2.1e-49 168.3 0.0 3e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 Lyase ASL_C PF08328.6 KEG13394.1 - 8.1e-45 151.3 0.0 1.6e-44 150.3 0.0 1.5 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal Peptidase_C2 PF00648.16 KEG13395.1 - 1.4e-47 162.1 0.0 2.3e-47 161.4 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 KEG13395.1 - 5.9e-35 119.3 0.7 2.5e-34 117.3 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1935) Lectin_C PF00059.16 KEG13396.1 - 3.8e-10 40.3 0.0 0.0002 21.9 0.0 3.0 2 0 0 2 2 2 2 Lectin C-type domain Toxin_64 PF15542.1 KEG13396.1 - 2.2 8.8 0.0 4.3 7.9 0.0 1.4 1 0 0 1 1 1 0 Putative toxin 64 TPR_2 PF07719.12 KEG13397.1 - 4.5e-10 38.6 3.4 0.00021 20.9 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 KEG13397.1 - 2.8e-07 30.0 5.0 0.0045 16.6 0.1 3.8 3 0 0 3 3 3 3 TPR repeat TPR_16 PF13432.1 KEG13397.1 - 7.4e-06 26.4 29.0 0.011 16.3 0.6 5.2 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 KEG13397.1 - 8.8e-05 22.0 0.3 0.019 14.7 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEG13397.1 - 0.00016 21.2 3.3 1.1 9.2 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEG13397.1 - 0.00029 20.7 2.3 2.6 8.0 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KEG13397.1 - 0.00071 19.9 20.1 0.14 12.8 0.6 5.3 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 KEG13397.1 - 0.0039 17.0 15.4 4.3 7.2 0.1 4.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 KEG13397.1 - 0.035 13.7 7.7 0.24 11.0 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEG13397.1 - 0.3 11.6 7.6 0.98 10.0 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat UBA PF00627.26 KEG13397.1 - 0.54 10.1 5.0 1.2 9.0 0.2 3.6 3 0 0 3 3 3 0 UBA/TS-N domain SNAP PF14938.1 KEG13397.1 - 0.87 8.6 9.5 29 3.6 6.6 2.3 1 1 0 1 1 1 0 Soluble NSF attachment protein, SNAP MIT PF04212.13 KEG13397.1 - 3 7.7 17.4 6.7 6.6 0.4 5.2 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain Alkyl_sulf_dimr PF14863.1 KEG13397.1 - 6.8 6.9 7.0 3.6 7.8 0.2 2.8 3 1 0 3 3 3 0 Alkyl sulfatase dimerisation Toxin_54 PF15533.1 KEG13401.1 - 0.074 13.3 0.1 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative toxin 54 ETF PF01012.16 KEG13402.1 - 5.6e-36 123.7 0.6 7.6e-36 123.3 0.4 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain GTP_EFTU PF00009.22 KEG13403.1 - 2.4e-49 167.3 0.0 4.3e-49 166.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 KEG13403.1 - 8.1e-14 51.2 0.0 2.1e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.18 KEG13403.1 - 0.00025 21.0 0.1 0.00048 20.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.13 KEG13403.1 - 0.0026 16.8 0.0 0.0039 16.2 0.0 1.2 1 0 0 1 1 1 1 Septin Miro PF08477.8 KEG13403.1 - 0.003 18.0 0.0 0.0058 17.1 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU_D2 PF03144.20 KEG13403.1 - 0.0035 17.4 0.6 0.012 15.6 0.4 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 DUF2293 PF10056.4 KEG13403.1 - 0.011 15.6 1.1 0.025 14.5 0.8 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2293) EFG_II PF14492.1 KEG13403.1 - 0.093 12.5 0.1 0.23 11.3 0.1 1.7 1 0 0 1 1 1 0 Elongation Factor G, domain II RNA_pol_Rpb6 PF01192.17 KEG13404.1 - 3.7e-12 45.7 0.2 2e-11 43.4 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb6 Tropomyosin_1 PF12718.2 KEG13406.1 - 0.0031 17.3 8.0 0.0031 17.3 5.6 2.1 2 1 0 2 2 2 1 Tropomyosin like Filament PF00038.16 KEG13406.1 - 0.0046 16.4 13.5 0.023 14.1 4.1 2.1 2 0 0 2 2 2 2 Intermediate filament protein DUF4200 PF13863.1 KEG13406.1 - 0.0049 16.8 4.3 0.0049 16.8 3.0 2.6 2 1 1 3 3 3 1 Domain of unknown function (DUF4200) Jnk-SapK_ap_N PF09744.4 KEG13406.1 - 0.0049 16.8 1.7 0.0049 16.8 1.2 2.7 2 1 1 3 3 3 1 JNK_SAPK-associated protein-1 DUF745 PF05335.8 KEG13406.1 - 0.0069 15.9 3.0 0.0099 15.4 0.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF745) Myosin_tail_1 PF01576.14 KEG13406.1 - 0.012 13.4 11.5 0.0045 14.7 5.0 2.0 2 1 0 2 2 2 0 Myosin tail TMF_DNA_bd PF12329.3 KEG13406.1 - 0.012 15.4 10.1 0.4 10.5 0.0 4.2 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding MbeD_MobD PF04899.7 KEG13406.1 - 0.012 15.4 11.3 4.8 7.1 0.5 4.3 3 1 1 4 4 4 0 MbeD/MobD like DUF1664 PF07889.7 KEG13406.1 - 0.048 13.4 2.7 0.83 9.4 0.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3584 PF12128.3 KEG13406.1 - 0.058 10.7 7.0 0.076 10.3 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc7 PF08317.6 KEG13406.1 - 0.072 11.7 4.2 0.14 10.7 2.3 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein Laminin_II PF06009.7 KEG13406.1 - 0.079 12.7 2.2 0.11 12.2 0.4 1.9 2 0 0 2 2 2 0 Laminin Domain II CENP-F_leu_zip PF10473.4 KEG13406.1 - 0.081 12.7 11.2 0.028 14.2 3.9 2.3 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_I PF06008.9 KEG13406.1 - 0.18 11.0 7.8 31 3.7 0.0 2.3 2 1 0 2 2 2 0 Laminin Domain I WXG100 PF06013.7 KEG13406.1 - 0.19 11.7 2.8 1.6 8.7 0.0 2.7 3 0 0 3 3 2 0 Proteins of 100 residues with WXG DUF948 PF06103.6 KEG13406.1 - 0.19 11.6 1.1 1.5 8.7 0.0 2.5 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) COG2 PF06148.6 KEG13406.1 - 0.23 11.3 2.6 0.79 9.5 0.9 2.3 2 1 0 2 2 1 0 COG (conserved oligomeric Golgi) complex component, COG2 V_ATPase_I PF01496.14 KEG13406.1 - 0.25 9.1 0.8 0.36 8.6 0.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 KEG13406.1 - 0.32 9.9 8.7 0.088 11.8 4.1 1.4 2 0 0 2 2 2 0 Autophagy protein Apg6 KLRAQ PF10205.4 KEG13406.1 - 0.32 11.0 9.4 3 7.9 0.0 3.4 3 1 1 4 4 4 0 Predicted coiled-coil domain-containing protein TMCO5 PF14992.1 KEG13406.1 - 0.53 9.3 8.9 0.47 9.5 4.6 1.8 1 1 0 2 2 2 0 TMCO5 family DivIC PF04977.10 KEG13406.1 - 0.58 9.6 11.6 1.7 8.1 0.4 3.7 4 0 0 4 4 4 0 Septum formation initiator ATG16 PF08614.6 KEG13406.1 - 0.58 9.9 12.1 9.2 6.0 5.5 3.0 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) MscS_porin PF12795.2 KEG13406.1 - 0.59 9.3 8.0 0.18 11.1 2.6 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Mnd1 PF03962.10 KEG13406.1 - 0.62 9.7 7.1 1.4 8.5 3.0 2.5 2 1 0 2 2 2 0 Mnd1 family DUF972 PF06156.8 KEG13406.1 - 0.63 10.4 7.5 1.6 9.0 0.5 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF972) ADIP PF11559.3 KEG13406.1 - 0.71 9.7 11.8 0.23 11.3 4.5 2.4 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding FadA PF09403.5 KEG13406.1 - 0.97 9.4 4.9 20 5.1 1.5 3.0 1 1 2 3 3 3 0 Adhesion protein FadA ERM PF00769.14 KEG13406.1 - 1.6 8.2 10.3 4.6 6.7 5.1 2.3 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF4140 PF13600.1 KEG13406.1 - 2.2 8.7 10.0 10 6.6 0.6 3.7 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DivIVA PF05103.8 KEG13406.1 - 2.8 8.0 6.5 46 4.0 2.4 3.3 2 1 1 3 3 3 0 DivIVA protein IncA PF04156.9 KEG13406.1 - 2.8 7.4 18.2 2.5 7.6 8.5 2.4 1 1 1 2 2 2 0 IncA protein TMF_TATA_bd PF12325.3 KEG13406.1 - 5.6 6.7 10.9 0.49 10.1 2.9 2.4 3 0 0 3 3 2 0 TATA element modulatory factor 1 TATA binding Spc24 PF08286.6 KEG13406.1 - 7.8 6.2 8.2 11 5.8 2.8 3.0 2 1 2 4 4 4 0 Spc24 subunit of Ndc80 CPSF100_C PF13299.1 KEG13407.1 - 4.2e-24 85.5 0.0 9.6e-24 84.3 0.0 1.6 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 KEG13407.1 - 1.8e-09 37.6 0.0 6.3e-09 35.8 0.0 1.9 2 0 0 2 2 2 1 Beta-Casp domain dsrm PF00035.20 KEG13408.1 - 0.02 15.4 0.0 1.3 9.6 0.0 3.1 2 0 0 2 2 2 0 Double-stranded RNA binding motif Peptidase_C12 PF01088.16 KEG13409.1 - 1.6e-56 190.8 0.0 5e-56 189.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 RepB-RCR_reg PF10723.4 KEG13409.1 - 0.022 14.5 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Replication regulatory protein RepB Clathrin PF00637.15 KEG13410.1 - 1.6e-07 30.9 4.2 0.035 13.6 0.2 5.1 3 2 3 6 6 6 2 Region in Clathrin and VPS TPR_7 PF13176.1 KEG13410.1 - 0.012 15.3 6.1 7.2 6.6 0.2 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat Apc3 PF12895.2 KEG13410.1 - 0.037 14.1 3.4 0.098 12.8 0.1 3.5 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 DZR PF12773.2 KEG13410.1 - 0.052 13.3 8.2 0.35 10.7 5.7 2.2 1 1 0 1 1 1 0 Double zinc ribbon PRP21_like_P PF12230.3 KEG13410.1 - 0.068 12.6 0.5 0.13 11.7 0.4 1.4 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein Mad3_BUB1_I PF08311.7 KEG13410.1 - 0.21 11.4 2.3 1.1 9.0 0.1 2.7 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 TPR_14 PF13428.1 KEG13410.1 - 0.34 11.6 7.7 6.7 7.6 0.1 5.8 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_11 PF13414.1 KEG13410.1 - 1.9 8.2 18.2 11 5.7 2.9 5.6 4 2 1 5 5 5 0 TPR repeat TPR_12 PF13424.1 KEG13410.1 - 3.5 7.6 12.3 3.4 7.6 0.3 5.2 5 1 1 6 6 6 0 Tetratricopeptide repeat WD40 PF00400.27 KEG13410.1 - 6.5 6.7 8.3 38 4.3 0.5 4.4 4 0 0 4 4 4 0 WD domain, G-beta repeat zf-RING_4 PF14570.1 KEG13410.1 - 6.6 6.3 11.2 4.1 7.0 5.8 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain TPR_2 PF07719.12 KEG13410.1 - 8.9 6.5 21.0 7.2 6.8 0.7 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat Mito_carr PF00153.22 KEG13411.1 - 4.5e-60 199.3 0.2 2.3e-20 72.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein NLBH PF05211.7 KEG13412.1 - 0.17 11.1 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Neuraminyllactose-binding hemagglutinin precursor (NLBH) GAGA PF09237.6 KEG13412.1 - 0.2 11.2 1.2 0.47 10.0 0.8 1.5 1 0 0 1 1 1 0 GAGA factor Spt5_N PF11942.3 KEG13412.1 - 0.32 11.6 6.2 0.82 10.3 0.3 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DSPc PF00782.15 KEG13413.1 - 9.8e-14 51.0 0.1 1.6e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KEG13413.1 - 0.013 14.8 0.1 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KEG13413.1 - 0.015 15.5 0.3 0.033 14.4 0.1 1.6 2 0 0 2 2 2 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KEG13413.1 - 0.026 14.5 0.3 0.051 13.6 0.0 1.7 2 0 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase2 PF03162.8 KEG13413.1 - 0.14 11.5 0.3 0.33 10.2 0.1 1.6 2 0 0 2 2 2 0 Tyrosine phosphatase family Bud13 PF09736.4 KEG13414.1 - 1.6e-05 25.1 0.0 2.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor of RES complex CCDC92 PF14916.1 KEG13415.1 - 0.00034 20.1 0.7 0.00034 20.1 0.5 3.0 3 1 1 4 4 4 1 Coiled-coil domain of unknown function MLANA PF14991.1 KEG13415.1 - 0.17 11.9 1.6 0.21 11.6 0.1 1.9 2 0 0 2 2 2 0 Protein melan-A HALZ PF02183.13 KEG13415.1 - 0.22 11.2 7.4 0.33 10.6 2.1 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper PDEase_I PF00233.14 KEG13418.1 - 4.1e-12 46.3 0.0 5.7e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Rhodanese PF00581.15 KEG13420.1 - 0.00065 20.0 0.0 0.0012 19.1 0.0 1.4 1 1 0 1 1 1 1 Rhodanese-like domain Topo_C_assoc PF14370.1 KEG13422.1 - 2.2e-28 97.7 0.1 3.6e-28 97.0 0.0 1.4 1 0 0 1 1 1 1 C-terminal topoisomerase domain CD99L2 PF12301.3 KEG13422.1 - 0.0052 16.4 5.7 0.0073 16.0 4.0 1.3 1 0 0 1 1 1 1 CD99 antigen like protein 2 DUF566 PF04484.7 KEG13422.1 - 0.086 12.3 9.1 0.1 12.0 6.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Macoilin PF09726.4 KEG13422.1 - 0.32 9.2 12.8 0.39 8.9 8.8 1.1 1 0 0 1 1 1 0 Transmembrane protein NPR3 PF03666.8 KEG13422.1 - 0.47 8.9 7.5 0.68 8.4 5.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.9 KEG13422.1 - 2 6.3 8.7 2.2 6.1 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 KEG13422.1 - 2.9 5.7 11.1 3.7 5.3 7.7 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1675 PF07897.6 KEG13422.1 - 6.7 6.4 12.1 10 5.9 8.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF3827 PF12877.2 KEG13422.1 - 9.6 4.1 10.6 12 3.8 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Nodulin-like PF06813.8 KEG13423.1 - 2.5e-08 33.4 29.5 2.8e-07 30.0 20.4 2.3 1 1 0 1 1 1 1 Nodulin-like Methyltransf_18 PF12847.2 KEG13425.1 - 1.6e-08 35.0 0.0 2.4e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEG13425.1 - 2.7e-05 23.8 0.0 3.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEG13425.1 - 0.00033 21.0 0.0 0.00052 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEG13425.1 - 0.018 15.4 0.0 0.028 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain A_thal_3526 PF09713.5 KEG13426.1 - 0.11 12.6 0.1 0.21 11.7 0.1 1.5 1 0 0 1 1 1 0 Plant protein 1589 of unknown function (A_thal_3526) FlxA PF14282.1 KEG13430.1 - 0.046 13.6 0.5 0.046 13.6 0.4 3.0 3 0 0 3 3 3 0 FlxA-like protein DivIVA PF05103.8 KEG13430.1 - 0.05 13.6 21.6 1.4 8.9 10.3 2.8 2 1 0 2 2 2 0 DivIVA protein FadA PF09403.5 KEG13430.1 - 8.8 6.3 27.6 0.17 11.9 5.5 3.0 2 1 1 3 3 3 0 Adhesion protein FadA IncA PF04156.9 KEG13433.1 - 0.039 13.5 18.3 0.073 12.6 12.7 1.3 1 0 0 1 1 1 0 IncA protein HALZ PF02183.13 KEG13433.1 - 0.11 12.2 8.3 0.12 12.1 1.8 2.5 1 1 1 2 2 2 0 Homeobox associated leucine zipper CAP_N PF01213.14 KEG13434.1 - 0.15 11.3 6.1 0.16 11.2 4.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 KEG13434.1 - 0.58 9.4 8.1 0.67 9.2 5.6 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator GRAM PF02893.15 KEG13435.1 - 1.5e-07 30.7 0.0 4.7e-07 29.2 0.0 1.8 1 1 0 1 1 1 1 GRAM domain LRR19-TM PF15176.1 KEG13435.1 - 0.13 11.9 0.2 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain PH_BEACH PF14844.1 KEG13435.1 - 0.22 11.3 1.1 0.31 10.8 0.0 1.8 2 0 0 2 2 2 0 PH domain associated with Beige/BEACH GTP_EFTU PF00009.22 KEG13437.1 - 8.3e-61 204.7 0.2 9.9e-61 204.4 0.2 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KEG13437.1 - 0.00029 20.7 0.0 0.00059 19.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Asp_protease PF09668.5 KEG13437.1 - 0.0038 16.8 0.2 1 8.9 0.0 2.4 2 0 0 2 2 2 2 Aspartyl protease SRPRB PF09439.5 KEG13437.1 - 0.07 12.3 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit EFG_IV PF03764.13 KEG13438.1 - 5.2e-35 119.6 0.0 1.2e-34 118.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 KEG13438.1 - 2.2e-21 75.5 0.0 4.4e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 KEG13438.1 - 8e-14 51.2 0.0 1.9e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 KEG13438.1 - 6.9e-13 48.5 0.1 1.7e-12 47.2 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 P21-Arc PF04062.9 KEG13440.1 - 1.2e-37 129.4 0.0 1.4e-37 129.1 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit DUF2225 PF09986.4 KEG13440.1 - 0.14 11.5 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) His_Phos_1 PF00300.17 KEG13442.1 - 1.1e-27 97.0 0.0 2e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 KEG13442.1 - 0.18 11.0 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Pkinase PF00069.20 KEG13443.1 - 9.9e-06 24.8 0.0 1.5e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG13443.1 - 0.089 11.8 0.0 12 4.9 0.0 2.5 3 0 0 3 3 3 0 Protein tyrosine kinase PUB PF09409.5 KEG13444.1 - 2e-13 49.9 0.0 4.5e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 PUB domain PLRV_ORF5 PF01690.12 KEG13444.1 - 0.55 9.3 3.8 0.7 8.9 2.7 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Pox_MCEL PF03291.11 KEG13445.1 - 3.7e-33 114.8 0.0 1.6e-22 79.8 0.0 2.0 2 0 0 2 2 2 2 mRNA capping enzyme Methyltransf_12 PF08242.7 KEG13445.1 - 0.001 19.4 0.0 0.0017 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEG13445.1 - 0.0089 16.3 0.1 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEG13445.1 - 0.01 15.4 0.0 0.026 14.1 0.0 1.7 2 1 0 2 2 2 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 KEG13445.1 - 0.013 14.4 0.1 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_18 PF12847.2 KEG13445.1 - 0.02 15.4 0.0 0.04 14.5 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain CFC PF09443.5 KEG13445.1 - 0.077 12.6 0.2 0.19 11.3 0.2 1.7 1 0 0 1 1 1 0 Cripto_Frl-1_Cryptic (CFC) MH2 PF03166.9 KEG13446.1 - 0.01 15.6 0.0 0.052 13.3 0.0 2.1 1 1 0 1 1 1 0 MH2 domain IMS PF00817.15 KEG13447.1 - 1e-37 129.2 0.3 2e-37 128.2 0.2 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KEG13447.1 - 0.00012 22.0 0.0 0.00032 20.6 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KEG13447.1 - 0.00074 19.4 0.0 0.06 13.4 0.0 2.7 2 0 0 2 2 2 1 IMS family HHH motif DUF844 PF05815.6 KEG13447.1 - 0.12 11.2 0.1 0.24 10.2 0.1 1.4 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) LCM PF04072.9 KEG13449.1 - 3.7e-27 95.0 0.0 5.5e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase TPR_11 PF13414.1 KEG13450.1 - 7.5e-46 153.6 12.7 4.8e-17 61.3 0.7 4.2 2 2 1 4 4 4 4 TPR repeat TPR_1 PF00515.23 KEG13450.1 - 1.9e-41 138.0 11.6 1.5e-08 33.8 0.0 6.9 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 KEG13450.1 - 4e-34 113.7 6.8 9.5e-07 28.2 0.0 6.4 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.1 KEG13450.1 - 7.3e-18 64.2 6.0 0.00043 20.1 2.1 5.0 3 1 1 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.1 KEG13450.1 - 2.9e-17 61.0 9.6 0.00086 18.9 0.0 6.2 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 KEG13450.1 - 1.1e-14 53.6 0.1 0.0007 20.0 0.0 5.1 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 KEG13450.1 - 1.8e-14 53.9 6.4 0.00017 22.1 0.1 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 KEG13450.1 - 6.8e-13 48.2 0.0 8e-05 22.4 0.0 3.9 2 2 2 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 KEG13450.1 - 9.5e-13 48.1 6.1 3.7e-06 26.9 2.3 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KEG13450.1 - 1.2e-12 46.6 1.7 0.047 13.5 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 KEG13450.1 - 1.2e-11 43.8 2.1 0.022 14.9 0.2 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 KEG13450.1 - 2.2e-10 40.2 0.6 0.015 15.7 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEG13450.1 - 7.7e-09 35.7 9.9 0.015 15.5 0.1 4.4 3 1 2 5 5 5 2 Tetratricopeptide repeat DUF3856 PF12968.2 KEG13450.1 - 6.7e-06 25.9 2.2 0.085 12.6 0.0 4.1 3 2 0 4 4 4 1 Domain of Unknown Function (DUF3856) MIT PF04212.13 KEG13450.1 - 9e-06 25.4 12.2 0.027 14.3 0.2 4.8 4 1 0 4 4 4 2 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 KEG13450.1 - 0.00014 21.5 1.2 1.4 8.8 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 KEG13450.1 - 0.00015 20.8 0.0 1.2 8.4 0.0 4.9 6 0 0 6 6 6 1 SHNi-TPR SPO22 PF08631.5 KEG13450.1 - 0.00025 20.2 3.4 1.8 7.5 0.0 3.2 3 0 0 3 3 3 2 Meiosis protein SPO22/ZIP4 like Fis1_TPR_C PF14853.1 KEG13450.1 - 0.00026 20.8 2.2 0.032 14.1 0.1 4.1 5 1 0 5 5 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.1 KEG13450.1 - 0.00033 19.8 1.7 0.72 8.8 0.0 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat RPN7 PF10602.4 KEG13450.1 - 0.0038 16.6 3.3 0.0038 16.6 2.3 2.5 2 1 1 3 3 3 1 26S proteasome subunit RPN7 Sel1 PF08238.7 KEG13450.1 - 0.036 14.6 4.2 4.5 8.0 0.1 3.9 4 0 0 4 4 4 0 Sel1 repeat TPR_10 PF13374.1 KEG13450.1 - 0.055 13.4 5.2 44 4.1 0.0 5.0 6 0 0 6 6 5 0 Tetratricopeptide repeat TOM20_plant PF06552.7 KEG13450.1 - 0.099 12.2 2.4 0.49 9.9 0.1 2.7 2 1 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 SAP PF02037.22 KEG13451.1 - 9.5e-10 37.7 0.2 1.5e-09 37.0 0.2 1.3 1 0 0 1 1 1 1 SAP domain FGGY_C PF02782.11 KEG13452.1 - 7.8e-40 136.6 0.1 1.2e-39 135.9 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KEG13452.1 - 4.1e-10 39.3 0.0 2.8e-09 36.6 0.0 2.4 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain PUF PF00806.14 KEG13453.1 - 5.9e-38 126.2 7.8 1.6e-07 30.4 0.1 7.5 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat NatB_MDM20 PF09797.4 KEG13453.1 - 0.00052 18.8 0.2 0.0011 17.7 0.1 1.5 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit YhzD PF14120.1 KEG13454.1 - 0.13 12.1 0.1 0.33 10.8 0.0 1.7 2 0 0 2 2 2 0 YhzD-like protein RHSP PF07999.6 KEG13455.1 - 3e-66 223.8 0.3 3.8e-66 223.5 0.2 1.1 1 0 0 1 1 1 1 Retrotransposon hot spot protein AAA_10 PF12846.2 KEG13455.1 - 0.029 13.8 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.1 KEG13455.1 - 0.13 12.4 0.0 1.6 8.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain Snf7 PF03357.16 KEG13456.1 - 4.3e-35 120.6 16.0 5e-35 120.4 11.1 1.0 1 0 0 1 1 1 1 Snf7 WEMBL PF05701.6 KEG13456.1 - 6.7e-06 24.8 10.9 8.5e-06 24.4 7.6 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light DUF848 PF05852.6 KEG13456.1 - 0.0047 16.7 7.7 0.0056 16.5 4.7 1.6 1 1 0 1 1 1 1 Gammaherpesvirus protein of unknown function (DUF848) NPV_P10 PF05531.7 KEG13456.1 - 0.031 14.5 3.3 0.12 12.6 0.9 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Dak2 PF02734.12 KEG13456.1 - 0.042 13.5 0.8 0.069 12.8 0.5 1.3 1 0 0 1 1 1 0 DAK2 domain DUF1664 PF07889.7 KEG13456.1 - 6 6.6 11.1 3.5 7.4 1.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Ribosomal_L18ae PF01775.12 KEG13458.1 - 6.9e-40 135.7 0.8 1e-39 135.2 0.6 1.3 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain CTP_transf_2 PF01467.21 KEG13459.1 - 3.5e-31 108.3 0.0 1.1e-14 54.7 0.0 2.6 2 1 0 2 2 2 2 Cytidylyltransferase FAD_syn PF06574.7 KEG13459.1 - 0.00025 20.6 0.9 0.34 10.5 0.0 3.1 3 0 0 3 3 3 2 FAD synthetase Neuroparsin PF07327.6 KEG13459.1 - 0.087 13.0 0.7 0.41 10.8 0.1 2.3 2 1 1 3 3 3 0 Neuroparsin Abhydrolase_6 PF12697.2 KEG13461.1 - 8.8e-28 97.7 1.5 1.1e-27 97.3 1.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEG13461.1 - 4.2e-09 36.3 0.8 1.7e-08 34.3 0.5 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEG13461.1 - 2.9e-06 26.9 0.1 2e-05 24.2 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KEG13461.1 - 0.00017 21.2 0.1 0.00032 20.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KEG13461.1 - 0.0011 18.2 0.1 0.003 16.8 0.0 1.7 1 1 1 2 2 2 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 KEG13461.1 - 0.0073 15.2 0.2 0.024 13.5 0.1 1.8 1 1 0 1 1 1 1 Chlorophyllase enzyme PGAP1 PF07819.8 KEG13461.1 - 0.012 15.1 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 KEG13461.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Ser_hydrolase PF06821.8 KEG13461.1 - 0.026 14.1 0.0 0.066 12.8 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase Hydrolase_4 PF12146.3 KEG13461.1 - 0.034 14.0 0.5 5.8 6.8 0.0 2.5 2 0 0 2 2 2 0 Putative lysophospholipase PAF-AH_p_II PF03403.8 KEG13461.1 - 0.14 10.3 0.0 0.22 9.7 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II TP53IP5 PF15331.1 KEG13461.1 - 0.18 11.7 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 V_ATPase_I PF01496.14 KEG13462.1 - 1.1e-144 483.2 0.0 1.2e-144 483.0 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family UPF0184 PF03670.8 KEG13462.1 - 0.082 13.0 2.3 1.1 9.5 0.2 3.0 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0184) MtrG PF04210.8 KEG13462.1 - 2.5 7.8 4.8 10 5.8 0.0 3.3 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G DAO PF01266.19 KEG13464.1 - 1.1e-05 24.5 0.2 0.0029 16.5 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEG13464.1 - 4.5e-05 23.6 0.0 0.0001 22.4 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 KEG13464.1 - 0.00012 21.3 0.1 1.1 8.3 0.0 3.2 2 1 0 3 3 3 2 GMC oxidoreductase NAD_binding_8 PF13450.1 KEG13464.1 - 0.00012 21.9 0.4 0.00012 21.9 0.3 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KEG13464.1 - 0.0015 18.4 0.1 0.0031 17.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEG13464.1 - 0.0024 16.8 0.2 0.0037 16.2 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 KEG13464.1 - 0.0031 16.6 0.0 0.0055 15.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 KEG13464.1 - 0.0036 17.0 0.1 0.0074 16.0 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding HI0933_like PF03486.9 KEG13464.1 - 0.0048 15.4 0.0 0.0077 14.7 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 KEG13464.1 - 0.0076 15.1 1.4 0.068 12.0 0.4 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.14 KEG13464.1 - 0.012 14.7 0.1 0.021 13.9 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 KEG13464.1 - 0.079 11.5 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GMC_oxred_C PF05199.8 KEG13464.1 - 0.087 13.1 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 GMC oxidoreductase CLASP_N PF12348.3 KEG13465.1 - 7.1e-22 77.8 0.1 3.2e-19 69.1 0.0 3.0 2 1 1 3 3 3 2 CLASP N terminal HEAT_2 PF13646.1 KEG13465.1 - 0.0014 18.9 19.2 0.14 12.4 0.0 7.0 4 2 2 6 6 6 2 HEAT repeats HEAT PF02985.17 KEG13465.1 - 1.5 9.0 12.6 31 5.0 0.0 6.2 6 0 0 6 6 6 0 HEAT repeat SNase PF00565.12 KEG13466.1 - 4.5e-41 139.4 0.0 1.1e-09 38.4 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 KEG13466.1 - 2.7e-16 59.5 0.0 6.2e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Tudor domain NA37 PF04245.8 KEG13466.1 - 0.16 11.2 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 37-kD nucleoid-associated bacterial protein UQ_con PF00179.21 KEG13467.1 - 1.2e-37 128.4 0.0 1.6e-37 128.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Peptidase_C2 PF00648.16 KEG13468.1 - 0.00025 20.1 0.0 0.0023 17.0 0.0 2.2 2 1 1 3 3 3 1 Calpain family cysteine protease DUF1295 PF06966.7 KEG13470.1 - 1.7e-29 102.7 9.3 2.5e-29 102.2 6.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) HemY_N PF07219.8 KEG13470.1 - 0.93 9.0 3.9 1.3 8.5 0.1 2.8 2 1 0 2 2 2 0 HemY protein N-terminus Acyl-CoA_dh_1 PF00441.19 KEG13471.1 - 2.7e-06 27.5 0.1 3.5e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 KEG13471.1 - 0.0039 17.4 0.0 0.0052 17.0 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Spore_III_AE PF09546.5 KEG13471.1 - 0.042 12.8 0.0 0.049 12.5 0.0 1.0 1 0 0 1 1 1 0 Stage III sporulation protein AE (spore_III_AE) XRN_N PF03159.13 KEG13472.1 - 2.9e-16 59.5 0.0 3e-15 56.2 0.0 2.0 1 1 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XPG_N PF00752.12 KEG13472.1 - 0.097 12.9 0.0 0.64 10.3 0.0 2.0 2 0 0 2 2 2 0 XPG N-terminal domain ARD PF03079.9 KEG13474.1 - 5.6e-16 58.8 0.0 8.3e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 ARD/ARD' family DUF953 PF06110.6 KEG13474.1 - 4.9e-13 48.5 0.0 8.2e-13 47.8 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Cupin_2 PF07883.6 KEG13474.1 - 2.2e-06 27.0 0.0 7.9e-06 25.2 0.0 1.9 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 KEG13474.1 - 0.0013 18.3 0.2 0.0037 16.9 0.1 1.6 1 1 0 1 1 1 1 Cupin Cupin_3 PF05899.7 KEG13474.1 - 0.013 14.9 0.0 0.031 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) AraC_binding PF02311.14 KEG13474.1 - 0.032 13.9 0.0 0.072 12.7 0.0 1.6 1 0 0 1 1 1 0 AraC-like ligand binding domain DUF4350 PF14258.1 KEG13474.1 - 0.089 13.0 0.1 0.36 11.0 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) DUF4200 PF13863.1 KEG13478.1 - 1.1 9.1 8.3 4.3 7.2 5.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Unstab_antitox PF09720.5 KEG13478.1 - 2.2 8.0 10.9 24 4.7 3.0 3.1 2 1 1 3 3 3 0 Putative addiction module component TatD_DNase PF01026.16 KEG13480.1 - 8.2e-45 152.9 0.0 9.6e-45 152.7 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.9 KEG13480.1 - 0.0051 16.4 0.0 0.21 11.1 0.0 2.4 1 1 0 2 2 2 1 Amidohydrolase Pinin_SDK_memA PF04696.8 KEG13481.1 - 0.0036 16.8 1.6 0.0085 15.6 1.1 1.5 1 0 0 1 1 1 1 pinin/SDK/memA/ protein conserved region Fusion_gly PF00523.13 KEG13481.1 - 0.021 12.9 0.0 0.064 11.3 0.0 1.7 2 0 0 2 2 2 0 Fusion glycoprotein F0 Bact_transglu_N PF08379.5 KEG13483.1 - 0.13 12.5 0.2 0.57 10.5 0.2 1.9 2 0 0 2 2 2 0 Bacterial transglutaminase-like N-terminal region CRPV_capsid PF08762.5 KEG13483.1 - 0.19 11.1 1.1 1.1 8.6 0.8 2.0 1 1 0 1 1 1 0 CRPV capsid protein like DUF4589 PF15252.1 KEG13485.1 - 0.026 14.3 1.0 0.028 14.2 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) CAML PF14963.1 KEG13485.1 - 0.07 12.4 0.0 0.085 12.2 0.0 1.1 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Asp-B-Hydro_N PF05279.6 KEG13487.1 - 9.5 5.9 19.5 16 5.2 13.5 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region AAA PF00004.24 KEG13489.1 - 3.4e-87 289.3 0.0 5.3e-48 162.5 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KEG13489.1 - 3.5e-15 55.7 0.0 5.7e-08 32.0 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KEG13489.1 - 3.5e-13 49.9 2.6 5.6e-05 23.2 0.0 4.7 4 2 2 6 6 4 2 AAA ATPase domain AAA_5 PF07728.9 KEG13489.1 - 5.3e-11 42.3 0.1 0.00027 20.6 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KEG13489.1 - 2.8e-10 40.3 0.0 2.8e-05 24.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KEG13489.1 - 3.4e-10 40.1 0.3 0.0024 18.0 0.0 4.4 2 2 1 3 3 3 2 AAA domain AAA_14 PF13173.1 KEG13489.1 - 1.4e-09 37.9 0.0 0.0013 18.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KEG13489.1 - 1.6e-09 37.1 0.0 3.9e-05 22.8 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin AAA_33 PF13671.1 KEG13489.1 - 2.3e-09 37.2 0.0 0.00089 19.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KEG13489.1 - 4.2e-08 34.0 0.0 0.0012 19.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KEG13489.1 - 1.1e-07 31.4 1.0 0.016 14.9 0.1 2.8 2 0 0 2 2 2 2 Part of AAA domain RNA_helicase PF00910.17 KEG13489.1 - 3.9e-07 30.2 0.0 0.027 14.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.7 KEG13489.1 - 3.9e-06 26.6 0.7 0.093 12.3 0.0 3.8 5 0 0 5 5 4 2 NACHT domain IstB_IS21 PF01695.12 KEG13489.1 - 4.1e-06 26.3 0.0 0.027 13.8 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.1 KEG13489.1 - 5.8e-06 26.3 0.0 0.11 12.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 KEG13489.1 - 9.4e-06 24.9 0.1 0.043 12.9 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 KEG13489.1 - 1.4e-05 25.4 0.0 0.3 11.3 0.0 2.8 2 1 0 2 2 2 2 ABC transporter TIP49 PF06068.8 KEG13489.1 - 1.5e-05 23.9 0.0 0.12 11.0 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus Viral_helicase1 PF01443.13 KEG13489.1 - 3.4e-05 23.4 0.0 0.2 11.1 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.1 KEG13489.1 - 3.9e-05 23.9 0.0 0.12 12.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.6 KEG13489.1 - 9.2e-05 22.0 0.0 0.35 10.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 KEG13489.1 - 0.00014 21.5 0.4 0.093 12.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain Sigma54_activ_2 PF14532.1 KEG13489.1 - 0.00015 21.8 0.0 0.026 14.5 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_11 PF13086.1 KEG13489.1 - 0.00029 20.4 0.0 0.2 11.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KEG13489.1 - 0.00038 19.9 4.2 1.5 8.1 0.1 3.9 2 2 1 4 4 4 2 AAA domain Rad17 PF03215.10 KEG13489.1 - 0.00043 19.1 0.3 0.19 10.3 0.0 2.8 2 1 1 3 3 3 1 Rad17 cell cycle checkpoint protein Sigma54_activat PF00158.21 KEG13489.1 - 0.00043 19.8 0.0 0.073 12.5 0.0 2.9 3 0 0 3 3 2 1 Sigma-54 interaction domain NB-ARC PF00931.17 KEG13489.1 - 0.0005 19.0 0.0 0.22 10.3 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain Arch_ATPase PF01637.13 KEG13489.1 - 0.00071 19.3 0.0 0.99 9.0 0.0 2.8 2 2 1 3 3 2 1 Archaeal ATPase Vps4_C PF09336.5 KEG13489.1 - 0.0012 18.7 0.0 0.007 16.2 0.0 2.2 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Parvo_NS1 PF01057.12 KEG13489.1 - 0.0012 17.7 0.0 0.33 9.7 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 UPF0079 PF02367.12 KEG13489.1 - 0.0016 18.0 0.0 2.4 7.7 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 NTPase_1 PF03266.10 KEG13489.1 - 0.0036 17.0 0.7 1 9.0 0.0 3.2 3 0 0 3 3 3 1 NTPase DUF815 PF05673.8 KEG13489.1 - 0.0046 15.9 0.0 2.6 6.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Bac_DnaA PF00308.13 KEG13489.1 - 0.0051 16.4 0.1 2.7 7.5 0.0 2.6 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_30 PF13604.1 KEG13489.1 - 0.0062 16.1 0.6 14 5.1 0.0 4.0 4 0 0 4 4 4 0 AAA domain SKI PF01202.17 KEG13489.1 - 0.024 14.5 0.0 0.41 10.4 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase ATP-synt_ab PF00006.20 KEG13489.1 - 0.028 13.9 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain KaiC PF06745.8 KEG13489.1 - 0.031 13.4 0.2 2 7.5 0.0 2.6 2 1 0 2 2 2 0 KaiC PhoH PF02562.11 KEG13489.1 - 0.065 12.4 0.5 4.1 6.5 0.0 2.9 3 0 0 3 3 3 0 PhoH-like protein CPT PF07931.7 KEG13489.1 - 0.072 12.7 0.0 8.5 5.9 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_23 PF13476.1 KEG13489.1 - 0.12 12.6 0.0 20 5.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 KEG13489.1 - 0.13 12.1 0.0 22 4.8 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DAP3 PF10236.4 KEG13489.1 - 0.13 11.1 0.0 7 5.4 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 PduV-EutP PF10662.4 KEG13489.1 - 0.19 11.1 0.1 18 4.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 KEG13489.1 - 0.2 11.1 0.5 11 5.4 0.0 2.5 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.13 KEG13489.1 - 0.21 10.8 0.3 4.9 6.4 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Ufd2P_core PF10408.4 KEG13491.1 - 1.1e-114 384.0 0.0 1.4e-114 383.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core Thioredoxin PF00085.15 KEG13491.1 - 1.4e-21 76.0 0.0 3.6e-21 74.7 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.11 KEG13491.1 - 0.00019 20.2 0.0 0.00035 19.3 0.0 1.4 1 0 0 1 1 1 1 Phosducin Thioredoxin_8 PF13905.1 KEG13491.1 - 0.00038 20.5 0.1 0.021 14.9 0.1 2.9 2 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KEG13491.1 - 0.052 13.7 0.9 0.45 10.7 0.6 2.5 1 1 0 1 1 1 0 Thioredoxin-like domain U-box PF04564.10 KEG13491.1 - 0.067 13.1 0.4 0.3 11.0 0.3 2.1 1 1 0 1 1 1 0 U-box domain Thioredoxin_7 PF13899.1 KEG13491.1 - 0.089 12.8 0.2 0.45 10.5 0.1 2.3 1 0 0 1 1 1 0 Thioredoxin-like AhpC-TSA PF00578.16 KEG13491.1 - 0.13 11.9 0.1 0.29 10.8 0.1 1.6 1 0 0 1 1 1 0 AhpC/TSA family Pkinase PF00069.20 KEG13492.1 - 6.4e-42 143.4 0.0 8.3e-41 139.8 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG13492.1 - 8.4e-25 87.3 0.0 6.7e-17 61.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KEG13492.1 - 0.00045 20.0 0.1 0.0068 16.1 0.1 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KEG13492.1 - 0.0089 15.0 0.5 0.15 11.0 0.0 2.2 1 1 0 2 2 2 1 Kinase-like PIP49_C PF12260.3 KEG13492.1 - 0.012 14.9 0.0 0.045 13.1 0.0 1.8 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 Mo25 PF08569.6 KEG13493.1 - 5.3e-70 236.0 0.0 6.3e-70 235.8 0.0 1.0 1 0 0 1 1 1 1 Mo25-like HEAT PF02985.17 KEG13493.1 - 0.11 12.6 0.4 34 4.8 0.0 3.4 4 0 0 4 4 4 0 HEAT repeat APG5 PF04106.7 KEG13494.1 - 0.0033 16.9 0.0 2.2 7.7 0.0 2.3 2 0 0 2 2 2 2 Autophagy protein Apg5 MAM33 PF02330.11 KEG13495.1 - 2e-20 73.4 1.1 2e-18 66.9 0.4 2.0 2 0 0 2 2 2 2 Mitochondrial glycoprotein WD40 PF00400.27 KEG13497.1 - 2e-24 84.5 7.0 2.6e-06 27.0 0.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KEG13497.1 - 5.8e-18 64.5 0.2 1.2e-17 63.5 0.2 1.5 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Glyco_hydro_101 PF12905.2 KEG13497.1 - 0.099 11.2 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Endo-alpha-N-acetylgalactosaminidase Spc97_Spc98 PF04130.8 KEG13498.1 - 1.3e-36 126.0 0.0 8.4e-36 123.3 0.0 1.9 1 1 0 1 1 1 1 Spc97 / Spc98 family DUF4604 PF15377.1 KEG13501.1 - 0.015 15.4 0.1 6.6 6.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) DUF4139 PF13598.1 KEG13503.1 - 5.7e-89 298.5 0.7 9e-89 297.9 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.1 KEG13503.1 - 5.6e-10 39.5 1.3 5.6e-10 39.5 0.9 2.8 3 0 0 3 3 3 1 N-terminal domain of unknown function (DUF4140) TPR_MLP1_2 PF07926.7 KEG13503.1 - 0.0017 18.0 0.0 0.0046 16.7 0.0 1.7 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein MitMem_reg PF13012.1 KEG13503.1 - 0.035 14.1 0.0 0.15 12.1 0.0 2.0 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function NPV_P10 PF05531.7 KEG13503.1 - 0.13 12.5 1.3 0.35 11.1 0.9 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Pox_A_type_inc PF04508.7 KEG13503.1 - 0.44 10.4 6.7 0.92 9.4 0.9 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Phage_GP20 PF06810.6 KEG13503.1 - 0.5 9.7 7.2 0.44 9.9 1.2 2.3 2 0 0 2 2 2 0 Phage minor structural protein GP20 IFRD PF05004.8 KEG13504.1 - 0.019 14.0 0.6 0.04 13.0 0.3 1.5 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) DUF1910 PF08928.5 KEG13504.1 - 0.043 13.8 0.0 0.09 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) PPR_3 PF13812.1 KEG13504.1 - 3 8.3 7.3 25 5.4 0.0 4.4 5 1 0 5 5 5 0 Pentatricopeptide repeat domain HECT PF00632.20 KEG13505.1 - 2.7e-76 256.7 0.0 3.6e-76 256.3 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Guanylate_cyc PF00211.15 KEG13507.1 - 3.5e-46 156.8 0.0 5.8e-46 156.1 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Fez1 PF06818.10 KEG13509.1 - 0.0043 17.0 13.2 0.0096 15.9 9.2 1.6 1 1 0 1 1 1 1 Fez1 CALCOCO1 PF07888.6 KEG13509.1 - 0.042 12.1 8.9 0.049 11.9 6.2 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like PRE_C2HC PF07530.6 KEG13509.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Associated with zinc fingers Nol1_Nop2_Fmu PF01189.12 KEG13510.1 - 3.6e-83 279.1 0.0 5e-83 278.7 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 KEG13510.1 - 0.00069 19.6 0.1 0.0022 18.0 0.0 1.9 2 1 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 KEG13510.1 - 0.00088 19.8 1.1 0.019 15.5 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEG13510.1 - 0.0031 17.1 0.0 0.0054 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Med3 PF11593.3 KEG13510.1 - 0.045 12.9 0.1 0.087 12.0 0.1 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PCEMA1 PF07418.6 KEG13510.1 - 0.89 8.8 5.1 1.5 8.1 3.5 1.2 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 V_ATPase_I PF01496.14 KEG13513.1 - 4.4 5.0 18.1 0.17 9.6 6.3 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family RNA_pol_Rpb2_6 PF00562.23 KEG13514.1 - 9.7e-121 403.1 0.0 1.3e-120 402.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KEG13514.1 - 2.1e-40 137.8 0.0 3.5e-40 137.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 KEG13514.1 - 5.3e-28 97.1 0.0 1.2e-27 95.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 KEG13514.1 - 8.5e-24 83.1 2.3 1.7e-23 82.1 1.6 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_2 PF04561.9 KEG13514.1 - 9e-24 83.9 0.0 1.7e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 KEG13514.1 - 6.9e-21 73.7 1.7 7.1e-21 73.7 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 KEG13514.1 - 4.6e-08 32.9 0.2 9.5e-08 31.8 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 OrfB_Zn_ribbon PF07282.6 KEG13514.1 - 0.13 11.8 4.1 0.13 11.9 1.6 1.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain UCH PF00443.24 KEG13517.1 - 3.1e-44 151.1 0.0 4.9e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEG13517.1 - 1.1e-11 44.6 0.0 3.6e-11 43.0 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 KEG13517.1 - 1.2e-06 27.8 0.5 3.4e-06 26.3 0.1 2.0 2 1 0 2 2 2 1 Ubiquitin family YukD PF08817.5 KEG13517.1 - 2.3e-06 28.0 0.1 6.3e-06 26.6 0.1 1.8 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD Ubiquitin_2 PF14560.1 KEG13517.1 - 0.016 15.4 0.0 0.042 14.1 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain DUF3450 PF11932.3 KEG13518.1 - 0.00054 19.3 11.0 0.00054 19.3 7.6 5.4 1 1 5 7 7 7 2 Protein of unknown function (DUF3450) GAS PF13851.1 KEG13518.1 - 0.00066 18.9 11.5 0.00066 18.9 8.0 4.9 1 1 3 4 4 4 2 Growth-arrest specific micro-tubule binding DUF3175 PF11373.3 KEG13519.1 - 0.0035 17.3 0.1 0.0055 16.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3175) Pkinase PF00069.20 KEG13520.1 - 2.3e-67 226.9 0.0 3.9e-67 226.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG13520.1 - 4.6e-31 107.8 0.0 6.6e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG13520.1 - 3.4e-07 29.5 0.0 3.9e-05 22.7 0.0 2.5 2 1 0 2 2 2 2 Kinase-like APH PF01636.18 KEG13520.1 - 0.00012 21.8 0.0 0.36 10.5 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family RHSP PF07999.6 KEG13523.1 - 5.5e-83 278.9 0.1 9.8e-83 278.1 0.1 1.3 1 0 0 1 1 1 1 Retrotransposon hot spot protein AAA_10 PF12846.2 KEG13523.1 - 0.0035 16.8 0.0 0.0056 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain Macro_2 PF14519.1 KEG13523.1 - 0.061 12.4 0.0 0.096 11.7 0.0 1.2 1 0 0 1 1 1 0 Macro-like domain Kinesin PF00225.18 KEG13525.1 - 2.1e-77 260.0 3.5 4.8e-77 258.9 0.1 2.7 2 1 0 2 2 2 1 Kinesin motor domain DUF3391 PF11871.3 KEG13525.1 - 1.8 8.7 5.7 0.65 10.2 1.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) GAS PF13851.1 KEG13525.1 - 6.7 5.8 9.2 0.15 11.2 0.5 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding RRM_1 PF00076.17 KEG13526.1 - 1.6e-14 53.2 0.0 2.8e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG13526.1 - 2.8e-13 49.6 0.0 5.6e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG13526.1 - 2.8e-06 27.0 0.0 4.3e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.3 KEG13526.1 - 0.013 15.8 1.2 0.014 15.7 0.1 1.6 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF1662 PF07878.6 KEG13526.1 - 0.056 13.1 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1662) MIF4G PF02854.14 KEG13527.1 - 4.4e-33 114.4 0.7 6.8e-33 113.8 0.5 1.2 1 0 0 1 1 1 1 MIF4G domain Band_7 PF01145.20 KEG13528.1 - 4.4e-22 78.8 3.6 5.8e-22 78.4 2.5 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family DUF4200 PF13863.1 KEG13528.1 - 0.021 14.7 5.7 0.025 14.5 1.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) WD40 PF00400.27 KEG13529.1 - 7.6e-07 28.7 4.1 0.021 14.6 0.0 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat DUF4164 PF13747.1 KEG13529.1 - 0.079 13.1 2.0 0.19 11.8 1.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) EKR PF10371.4 KEG13529.1 - 0.12 11.9 0.0 0.33 10.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function SlyX PF04102.7 KEG13529.1 - 0.26 11.6 0.1 0.26 11.6 0.1 2.1 2 0 0 2 2 2 0 SlyX Nop PF01798.13 KEG13530.1 - 2.9e-13 49.3 0.5 5e-13 48.6 0.4 1.3 1 0 0 1 1 1 1 Putative snoRNA binding domain Prp31_C PF09785.4 KEG13530.1 - 0.00025 21.4 2.7 0.00043 20.7 1.9 1.5 1 0 0 1 1 1 1 Prp31 C terminal domain TPR_12 PF13424.1 KEG13531.1 - 1.2e-06 28.3 17.9 0.0018 18.1 0.4 6.1 5 1 2 7 7 7 4 Tetratricopeptide repeat eIF3_p135 PF12807.2 KEG13531.1 - 7.8e-05 22.6 0.0 0.00026 20.9 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_11 PF13414.1 KEG13531.1 - 0.00035 20.1 9.1 0.059 13.0 0.2 4.7 4 0 0 4 4 4 2 TPR repeat IQ PF00612.22 KEG13531.1 - 0.0025 17.2 16.2 0.11 12.2 2.6 4.8 4 0 0 4 4 4 2 IQ calmodulin-binding motif TPR_14 PF13428.1 KEG13531.1 - 0.035 14.7 15.5 24 5.9 0.1 7.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 KEG13531.1 - 0.053 14.2 21.3 1.6 9.5 0.1 7.0 4 2 4 8 8 8 0 Tetratricopeptide repeat TPR_2 PF07719.12 KEG13531.1 - 0.16 11.9 13.4 3.6 7.7 0.3 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 KEG13531.1 - 0.3 10.9 6.2 27 4.8 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 KEG13531.1 - 8.8 6.4 23.3 3.3 7.7 0.4 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat CLU PF13236.1 KEG13532.1 - 3.2e-10 39.8 0.1 1.2e-08 34.6 0.0 2.3 1 1 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 KEG13532.1 - 0.0007 19.5 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 KEG13532.1 - 0.0013 18.6 0.6 0.009 15.9 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEG13532.1 - 0.0046 16.7 3.7 0.13 12.2 0.3 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 KEG13532.1 - 0.0081 15.7 0.2 0.36 10.5 0.0 2.6 2 0 0 2 2 2 1 TPR repeat CLU PF13236.1 KEG13533.1 - 2.5e-09 36.9 0.0 2.9e-08 33.3 0.0 2.4 1 1 0 1 1 1 1 Clustered mitochondria Ras PF00071.17 KEG13534.1 - 2.4e-46 157.0 0.0 2.8e-46 156.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Arf PF00025.16 KEG13534.1 - 3e-17 62.4 0.0 3.7e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 KEG13534.1 - 4.9e-17 62.5 0.0 8.7e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 KEG13534.1 - 1.6e-06 27.4 0.0 1.8e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KEG13534.1 - 4.8e-05 22.8 0.0 9.3e-05 21.9 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KEG13534.1 - 0.00014 21.7 0.0 0.0002 21.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KEG13534.1 - 0.003 16.7 0.1 0.0076 15.4 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 KEG13534.1 - 0.0031 16.9 0.0 0.0043 16.5 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain AAA_24 PF13479.1 KEG13534.1 - 0.0032 17.0 0.0 0.0048 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KEG13534.1 - 0.0086 15.5 0.0 0.023 14.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 KEG13534.1 - 0.022 14.2 0.1 0.11 11.9 0.0 1.9 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.1 KEG13534.1 - 0.027 13.8 0.0 0.053 12.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KEG13534.1 - 0.045 13.7 1.3 0.13 12.2 1.0 2.0 1 1 1 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 KEG13534.1 - 0.049 13.9 0.1 0.065 13.5 0.1 1.6 1 1 0 1 1 1 0 ABC transporter DUF815 PF05673.8 KEG13534.1 - 0.058 12.3 0.0 0.092 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.1 KEG13534.1 - 0.066 13.3 0.0 0.13 12.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain YTH PF04146.10 KEG13534.1 - 0.07 12.7 0.0 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 YT521-B-like domain MCM PF00493.18 KEG13534.1 - 0.07 11.9 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family G-alpha PF00503.15 KEG13534.1 - 0.086 11.5 0.3 3.6 6.1 0.1 2.3 1 1 0 2 2 2 0 G-protein alpha subunit AAA_23 PF13476.1 KEG13534.1 - 0.097 12.9 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KEG13534.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Hpr_kinase_C PF07475.7 KEG13534.1 - 0.19 11.0 0.3 0.32 10.2 0.2 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain DUF2517 PF10725.4 KEG13535.1 - 0.0084 15.7 0.0 5.5 6.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2517) Imp-YgjV PF10688.4 KEG13535.1 - 0.028 13.8 1.2 0.38 10.1 0.1 2.2 2 0 0 2 2 2 0 Bacterial inner membrane protein DUF2508 PF10704.4 KEG13535.1 - 0.074 13.2 0.2 5.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) Lectin_N PF03954.9 KEG13536.1 - 0.093 12.1 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF722 PF05263.6 KEG13537.1 - 0.029 14.5 0.6 0.074 13.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF722) TPR_14 PF13428.1 KEG13540.1 - 1.6e-08 34.4 13.6 0.26 12.0 0.1 8.1 5 2 3 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.1 KEG13540.1 - 3.6e-05 23.3 2.4 1.8 8.2 0.0 4.7 3 1 1 4 4 4 2 TPR repeat TPR_12 PF13424.1 KEG13540.1 - 0.0061 16.4 0.1 0.11 12.4 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEG13540.1 - 0.0075 16.1 0.6 0.48 10.4 0.1 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat PRP1_N PF06424.7 KEG13540.1 - 0.011 16.0 0.1 0.03 14.6 0.0 1.8 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal TPR_20 PF14561.1 KEG13540.1 - 0.036 14.1 1.5 0.15 12.1 0.1 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 KEG13540.1 - 0.049 13.8 0.0 18 5.8 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 KEG13540.1 - 0.12 12.2 0.0 0.88 9.4 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat ubiquitin PF00240.18 KEG13541.1 - 0.0017 17.6 0.0 0.0024 17.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family PAP_assoc PF03828.14 KEG13543.1 - 1.9e-12 46.9 0.0 3.5e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KEG13543.1 - 0.0053 17.0 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain NUDIX PF00293.23 KEG13544.1 - 1.7e-07 30.9 0.1 4e-07 29.7 0.1 1.7 1 1 0 1 1 1 1 NUDIX domain Nol1_Nop2_Fmu PF01189.12 KEG13545.1 - 1.4e-20 73.8 0.0 1.9e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 KEG13545.1 - 6.8e-05 22.8 0.1 0.00016 21.6 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEG13545.1 - 0.00072 20.1 0.0 0.0012 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KEG13545.1 - 0.12 12.4 0.0 0.23 11.4 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase TPR_12 PF13424.1 KEG13547.1 - 1.1e-06 28.5 0.9 1.1e-06 28.5 0.6 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 KEG13547.1 - 1.3e-06 27.9 0.4 1.3e-06 27.9 0.3 2.9 3 0 0 3 3 3 1 TPR repeat IQ PF00612.22 KEG13547.1 - 0.0028 17.1 2.5 0.0087 15.6 1.7 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif TPR_2 PF07719.12 KEG13547.1 - 0.0052 16.6 4.4 0.32 11.0 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEG13547.1 - 0.015 14.9 0.4 4.3 7.0 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 KEG13547.1 - 0.019 15.1 1.7 7 6.8 0.1 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 KEG13547.1 - 0.036 14.0 0.3 0.38 10.7 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Hist_deacetyl PF00850.14 KEG13548.1 - 2e-56 191.5 0.0 2.8e-56 191.1 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DUF2457 PF10446.4 KEG13548.1 - 0.83 8.3 13.9 1.2 7.7 9.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CobT PF06213.7 KEG13548.1 - 8.2 5.4 13.8 13 4.7 9.6 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT HAD_2 PF13419.1 KEG13549.1 - 1.8e-05 25.0 0.0 4.8e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KEG13549.1 - 3.3e-05 23.5 0.0 5.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KEG13549.1 - 0.077 13.3 0.0 0.12 12.8 0.0 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase MIP PF00230.15 KEG13551.1 - 8.9e-35 120.1 14.9 1.2e-34 119.8 10.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein vMSA PF00695.14 KEG13551.1 - 2.7 7.1 5.7 4.5 6.3 3.9 1.3 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus ABC_tran PF00005.22 KEG13553.1 - 3.6e-50 169.8 0.0 4.8e-30 104.6 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KEG13553.1 - 6.5e-41 140.5 16.8 1.6e-21 76.9 4.0 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_29 PF13555.1 KEG13553.1 - 7.5e-09 34.9 0.2 0.00088 18.7 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KEG13553.1 - 6.9e-08 32.4 0.0 0.014 15.3 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.14 KEG13553.1 - 7.6e-08 31.8 0.2 0.073 12.2 0.1 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 KEG13553.1 - 7.9e-07 28.3 0.0 0.019 14.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 KEG13553.1 - 2.4e-06 28.0 0.2 0.045 14.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 KEG13553.1 - 1.1e-05 25.0 0.0 0.15 11.5 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_17 PF13207.1 KEG13553.1 - 3.8e-05 24.4 0.0 0.099 13.4 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 KEG13553.1 - 4.5e-05 23.1 1.1 0.0084 15.7 0.1 2.8 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.1 KEG13553.1 - 4.6e-05 23.5 0.0 2.1 8.2 0.0 4.0 4 0 0 4 4 4 2 AAA domain Miro PF08477.8 KEG13553.1 - 5.9e-05 23.5 0.0 0.62 10.5 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein AAA_16 PF13191.1 KEG13553.1 - 8.2e-05 22.6 0.1 0.11 12.5 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.18 KEG13553.1 - 0.00013 21.8 1.0 0.027 14.2 0.2 2.6 2 0 0 2 2 2 1 Dynamin family AAA_18 PF13238.1 KEG13553.1 - 0.00014 22.2 0.0 0.17 12.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KEG13553.1 - 0.0004 20.2 0.1 0.019 14.8 0.0 2.9 3 0 0 3 3 2 1 AAA domain MobB PF03205.9 KEG13553.1 - 0.00084 19.0 0.1 0.42 10.3 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 KEG13553.1 - 0.0012 18.2 6.1 0.1 12.0 0.0 3.7 4 0 0 4 4 4 1 AAA domain AAA_22 PF13401.1 KEG13553.1 - 0.0017 18.4 0.2 0.61 10.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.12 KEG13553.1 - 0.0019 18.0 2.2 0.064 13.0 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 T2SE PF00437.15 KEG13553.1 - 0.0019 17.1 0.1 0.74 8.6 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein IstB_IS21 PF01695.12 KEG13553.1 - 0.0036 16.7 0.6 1.3 8.3 0.0 3.2 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_24 PF13479.1 KEG13553.1 - 0.0043 16.6 0.0 0.33 10.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KEG13553.1 - 0.0073 15.9 0.2 0.12 12.0 0.0 2.5 2 0 0 2 2 2 1 NACHT domain ArgK PF03308.11 KEG13553.1 - 0.01 14.6 0.1 1.7 7.3 0.0 2.2 2 0 0 2 2 2 0 ArgK protein Zeta_toxin PF06414.7 KEG13553.1 - 0.013 14.5 0.1 5.3 6.0 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.17 KEG13553.1 - 0.016 15.3 0.0 6.5 6.9 0.0 3.3 3 0 0 3 3 3 0 RNA helicase AAA_10 PF12846.2 KEG13553.1 - 0.018 14.4 0.1 1.2 8.5 0.1 2.4 2 0 0 2 2 2 0 AAA-like domain UPF0079 PF02367.12 KEG13553.1 - 0.03 13.9 0.4 0.81 9.3 0.0 2.8 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 IIGP PF05049.8 KEG13553.1 - 0.034 12.9 0.7 3.2 6.4 0.0 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Septin PF00735.13 KEG13553.1 - 0.034 13.1 0.0 0.3 10.0 0.0 2.0 2 0 0 2 2 2 0 Septin TrwB_AAD_bind PF10412.4 KEG13553.1 - 0.071 11.7 0.1 6.7 5.2 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain MutS_V PF00488.16 KEG13553.1 - 0.11 11.8 0.2 2.4 7.4 0.1 2.3 2 0 0 2 2 2 0 MutS domain V AAA_28 PF13521.1 KEG13553.1 - 0.15 12.0 0.1 13 5.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain DUF815 PF05673.8 KEG13553.1 - 0.22 10.3 0.0 1.4 7.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AIG1 PF04548.11 KEG13553.1 - 0.49 9.4 0.9 23 3.9 0.1 2.3 2 0 0 2 2 2 0 AIG1 family AAA_19 PF13245.1 KEG13553.1 - 0.87 9.3 5.3 2.1 8.1 0.1 3.6 3 0 0 3 3 3 0 Part of AAA domain CcmD PF04995.9 KEG13553.1 - 5.8 6.7 13.1 0.13 12.0 0.7 4.2 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) SIR2 PF02146.12 KEG13554.1 - 5.9e-48 162.9 0.0 7e-48 162.6 0.0 1.1 1 0 0 1 1 1 1 Sir2 family SIS PF01380.17 KEG13554.1 - 0.0011 18.6 0.0 0.0026 17.3 0.0 1.6 2 0 0 2 2 2 1 SIS domain Glyco_trans_1_4 PF13692.1 KEG13554.1 - 0.019 15.1 0.0 0.043 13.9 0.0 1.6 1 1 0 1 1 1 0 Glycosyl transferases group 1 TPP_enzyme_M PF00205.17 KEG13554.1 - 0.033 13.9 0.0 0.072 12.8 0.0 1.6 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain DoxX PF07681.7 KEG13555.1 - 0.00012 22.3 9.1 0.00014 22.1 5.4 1.6 2 0 0 2 2 2 1 DoxX SURF4 PF02077.10 KEG13555.1 - 0.073 12.4 1.9 0.089 12.1 1.3 1.3 1 0 0 1 1 1 0 SURF4 family PRA1 PF03208.14 KEG13555.1 - 0.71 9.1 7.0 0.88 8.8 4.9 1.2 1 0 0 1 1 1 0 PRA1 family protein ubiquitin PF00240.18 KEG13556.1 - 1.1e-18 66.3 0.0 1.2e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KEG13556.1 - 2e-11 43.3 0.1 2.3e-11 43.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KEG13556.1 - 8.6e-05 22.7 0.1 0.00026 21.1 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 KEG13556.1 - 0.00018 21.3 0.1 0.00079 19.2 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KEG13556.1 - 0.022 14.9 0.0 0.025 14.7 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain SNARE_assoc PF09335.6 KEG13557.1 - 0.036 14.2 2.8 4.5 7.5 0.1 2.3 2 0 0 2 2 2 0 SNARE associated Golgi protein PLDc_2 PF13091.1 KEG13558.1 - 4.5e-25 87.8 0.0 1.4e-17 63.5 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KEG13558.1 - 5.1e-10 38.8 3.5 6.2e-05 22.6 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif DUF2577 PF10844.3 KEG13561.1 - 0.04 13.9 0.0 0.091 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2577) DUF3596 PF12167.3 KEG13561.1 - 0.13 11.7 0.7 0.55 9.8 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3596) EST1_DNA_bind PF10373.4 KEG13562.1 - 0.009 15.2 0.6 0.017 14.3 0.4 1.5 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain Pkinase PF00069.20 KEG13563.1 - 3.5e-58 196.8 0.0 4.1e-58 196.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG13563.1 - 1.6e-29 102.8 0.0 4.2e-29 101.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG13563.1 - 0.0014 17.6 0.0 0.0025 16.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEG13563.1 - 0.062 13.0 0.0 1.2 8.7 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Reo_sigmaC PF04582.7 KEG13564.1 - 0.039 13.1 0.2 0.074 12.2 0.1 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DivIC PF04977.10 KEG13564.1 - 0.32 10.5 6.3 0.31 10.5 2.4 2.5 2 0 0 2 2 2 0 Septum formation initiator Mito_fiss_reg PF05308.6 KEG13565.1 - 0.096 12.0 10.3 0.4 9.9 2.1 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator DUF2203 PF09969.4 KEG13565.1 - 0.14 12.3 1.0 0.41 10.8 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) CAP_N PF01213.14 KEG13565.1 - 7.4 5.7 6.8 9 5.4 1.1 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DUF1935 PF09149.5 KEG13568.1 - 0.084 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1935) Propep_M14 PF02244.11 KEG13568.1 - 0.12 12.0 0.1 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Carboxypeptidase activation peptide Pkinase PF00069.20 KEG13570.1 - 8.1e-19 67.7 0.0 8.5e-19 67.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG13570.1 - 3.5e-14 52.4 0.0 3.7e-14 52.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG13570.1 - 0.024 13.6 0.0 0.024 13.5 0.0 1.1 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.17 KEG13570.1 - 0.033 13.5 0.0 0.04 13.2 0.0 1.0 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 KEG13570.1 - 0.039 13.0 0.0 0.044 12.8 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEG13570.1 - 0.088 12.5 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family HEAT_2 PF13646.1 KEG13571.1 - 0.0088 16.3 0.8 0.073 13.3 0.1 2.5 2 1 0 2 2 2 1 HEAT repeats Pkr1 PF08636.5 KEG13572.1 - 1.8e-08 34.3 4.3 2.3e-08 33.9 3.0 1.1 1 0 0 1 1 1 1 ER protein Pkr1 2TM PF13239.1 KEG13572.1 - 0.096 12.7 0.3 0.12 12.4 0.2 1.3 1 0 0 1 1 1 0 2TM domain DUF4175 PF13779.1 KEG13572.1 - 1.1 6.8 4.2 1.3 6.5 2.9 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4175) DUF2244 PF10003.4 KEG13572.1 - 2.6 7.3 4.9 3.4 7.0 3.4 1.2 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) PPR_3 PF13812.1 KEG13573.1 - 5.2e-21 73.1 3.6 2.8e-05 24.0 0.0 7.5 7 0 0 7 7 7 3 Pentatricopeptide repeat domain PPR_2 PF13041.1 KEG13573.1 - 1.1e-18 66.8 7.3 4.2e-06 26.6 0.0 6.9 7 1 1 8 8 8 3 PPR repeat family PPR PF01535.15 KEG13573.1 - 6.1e-10 38.3 8.8 0.0039 17.0 0.2 6.4 7 0 0 7 7 7 3 PPR repeat PPR_1 PF12854.2 KEG13573.1 - 7.5e-07 28.5 0.2 0.24 10.9 0.0 4.2 3 1 0 3 3 3 2 PPR repeat RPN7 PF10602.4 KEG13573.1 - 0.011 15.1 4.2 0.29 10.4 0.0 3.2 3 0 0 3 3 3 0 26S proteasome subunit RPN7 IF-2 PF11987.3 KEG13573.1 - 0.019 14.8 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 Translation-initiation factor 2 TPR_14 PF13428.1 KEG13573.1 - 0.79 10.5 3.3 15 6.5 0.1 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat F_actin_cap_B PF01115.12 KEG13574.1 - 2.4e-27 95.7 0.0 3.2e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Peptidase_M20 PF01546.23 KEG13575.1 - 5.3e-26 91.2 0.3 6.5e-26 90.9 0.2 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KEG13575.1 - 1.8e-09 37.3 0.0 5.6e-09 35.7 0.0 1.9 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KEG13575.1 - 0.023 14.4 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 Peptidase_M20 PF01546.23 KEG13576.1 - 3e-17 62.7 0.0 3.4e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.12 KEG13576.1 - 0.0084 15.8 0.0 0.011 15.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 Thi4 PF01946.12 KEG13576.1 - 0.068 12.2 0.0 0.07 12.2 0.0 1.1 1 0 0 1 1 1 0 Thi4 family M20_dimer PF07687.9 KEG13579.1 - 7.4e-10 38.5 0.0 1.2e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 KEG13579.1 - 1.4e-07 31.1 0.0 1.6e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 OST-HTH PF12872.2 KEG13580.1 - 0.0068 16.2 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 OST-HTH/LOTUS domain DCX PF03607.12 KEG13580.1 - 0.13 11.8 0.0 0.66 9.6 0.0 2.3 2 1 0 2 2 2 0 Doublecortin RNA_ligase PF09414.5 KEG13581.1 - 1.7e-52 177.9 0.0 1.2e-39 136.0 0.0 2.3 1 1 1 2 2 2 2 RNA ligase DNA_ligase_A_M PF01068.16 KEG13581.1 - 0.004 16.5 0.0 0.0084 15.4 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain FLILHELTA PF10306.4 KEG13581.1 - 0.056 13.4 0.0 0.34 10.9 0.0 2.2 2 0 0 2 2 2 0 Hypothetical protein FLILHELTA tRNA_U5-meth_tr PF05958.6 KEG13583.1 - 1.3e-16 60.2 0.0 1.2e-15 57.0 0.0 2.2 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 KEG13583.1 - 1.3e-13 50.8 0.0 2.3e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEG13583.1 - 2.7e-10 40.3 0.1 5.2e-10 39.3 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEG13583.1 - 1.1e-08 35.6 0.0 4.1e-08 33.8 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 KEG13583.1 - 3.2e-08 33.1 0.0 7.1e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KEG13583.1 - 1.2e-07 31.9 0.0 2.6e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 KEG13583.1 - 4.2e-06 26.2 0.0 7.6e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.7 KEG13583.1 - 5.4e-05 23.6 0.0 0.00012 22.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 KEG13583.1 - 0.00034 20.1 0.0 0.00055 19.5 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.8 KEG13583.1 - 0.00095 18.3 0.3 0.0019 17.3 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 KEG13583.1 - 0.0012 18.3 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 KEG13583.1 - 0.0028 16.7 0.0 0.0055 15.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family UPF0020 PF01170.13 KEG13583.1 - 0.0031 17.0 0.1 0.0055 16.2 0.1 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.12 KEG13583.1 - 0.0032 16.5 0.0 0.0066 15.5 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.1 KEG13583.1 - 0.0081 15.8 0.8 0.027 14.1 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEG13583.1 - 0.022 14.4 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KEG13583.1 - 0.074 13.5 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.6 KEG13583.1 - 0.097 12.0 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) TPMT PF05724.6 KEG13583.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) PAT1 PF09770.4 KEG13584.1 - 5.6 5.0 25.3 7.6 4.6 17.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SNAP PF14938.1 KEG13585.1 - 1.7e-58 198.0 19.1 2.2e-58 197.6 13.2 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 KEG13585.1 - 5.7e-07 29.3 14.3 6.8e-05 22.7 0.8 3.7 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEG13585.1 - 2.5e-06 26.8 10.4 0.022 14.5 0.0 6.6 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.1 KEG13585.1 - 4.7e-05 22.9 2.0 4.7e-05 22.9 1.4 4.8 5 2 1 6 6 6 2 TPR repeat TPR_14 PF13428.1 KEG13585.1 - 0.00015 22.1 11.4 3.2 8.6 0.0 5.9 2 1 5 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEG13585.1 - 0.00044 20.8 17.6 0.07 13.8 3.5 5.2 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEG13585.1 - 0.0012 19.1 15.3 0.071 13.4 0.3 4.2 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 KEG13585.1 - 0.0015 18.8 20.5 1.3 9.6 0.2 6.6 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 KEG13585.1 - 0.0068 15.9 16.1 0.37 10.4 0.1 5.6 5 1 1 6 6 6 2 Tetratricopeptide repeat Foie-gras_1 PF11817.3 KEG13585.1 - 0.0098 15.3 8.8 0.05 13.0 0.2 3.3 2 1 0 3 3 3 1 Foie gras liver health family 1 TPR_2 PF07719.12 KEG13585.1 - 0.0099 15.7 24.3 2.3 8.3 0.2 7.1 7 1 2 9 9 9 3 Tetratricopeptide repeat DUF627 PF04781.7 KEG13585.1 - 0.011 15.2 0.7 0.066 12.8 0.5 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF627) TPR_8 PF13181.1 KEG13585.1 - 0.021 14.5 15.5 8 6.5 0.1 6.4 6 1 1 7 7 7 0 Tetratricopeptide repeat PPR PF01535.15 KEG13585.1 - 0.035 14.0 3.3 5.8 7.1 0.0 4.3 4 0 0 4 4 4 0 PPR repeat TRAPPC-Trs85 PF12739.2 KEG13585.1 - 0.27 9.8 10.5 0.52 8.8 7.2 1.7 1 1 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit RPN7 PF10602.4 KEG13585.1 - 0.34 10.2 7.6 0.37 10.1 2.4 2.7 1 1 1 2 2 2 0 26S proteasome subunit RPN7 Apc3 PF12895.2 KEG13585.1 - 0.42 10.7 12.1 0.33 11.1 0.5 3.7 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 KEG13585.1 - 2.1 8.3 9.8 39 4.3 0.1 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat Peptidase_C50 PF03568.12 KEG13586.1 - 3.6e-37 127.9 0.0 6.9e-37 127.0 0.0 1.4 1 1 0 1 1 1 1 Peptidase family C50 CHAT PF12770.2 KEG13586.1 - 0.0013 17.9 0.0 0.0043 16.2 0.0 1.8 2 0 0 2 2 2 1 CHAT domain DUF2127 PF09900.4 KEG13587.1 - 0.097 12.6 0.1 0.12 12.3 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2127) PIP5K PF01504.13 KEG13588.1 - 1.5e-55 188.0 0.0 2.6e-55 187.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase FYVE PF01363.16 KEG13588.1 - 1.7e-14 53.4 6.7 4.6e-14 52.0 4.6 1.8 1 0 0 1 1 1 1 FYVE zinc finger Cpn60_TCP1 PF00118.19 KEG13588.1 - 1.3e-11 43.8 0.0 2e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family IBR PF01485.16 KEG13588.1 - 0.4 10.5 5.3 0.3 10.9 1.9 2.1 2 0 0 2 2 2 0 IBR domain E1_dh PF00676.15 KEG13589.1 - 8.2e-57 192.2 0.0 1.4e-56 191.4 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.19 KEG13589.1 - 1.1e-51 174.7 0.0 1.9e-51 174.1 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DUF1126 PF06565.7 KEG13591.1 - 3.5e-42 141.5 0.2 2.5e-14 52.4 0.0 3.7 3 0 0 3 3 3 3 Repeat of unknown function (DUF1126) EF-hand_7 PF13499.1 KEG13591.1 - 3.8e-07 30.1 0.1 5.3e-06 26.4 0.0 2.6 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 KEG13591.1 - 3.2e-05 23.4 0.2 0.0016 17.9 0.0 3.2 2 1 1 3 3 3 1 EF-hand domain pair DUF4319 PF14203.1 KEG13591.1 - 0.037 13.5 1.1 0.53 9.8 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4319) WD40 PF00400.27 KEG13592.1 - 2.2e-12 46.3 10.7 0.00066 19.4 0.1 7.0 6 1 0 6 6 6 5 WD domain, G-beta repeat TniQ PF06527.6 KEG13594.1 - 0.04 14.1 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 TniQ SOCS_box PF07525.11 KEG13594.1 - 0.43 10.4 6.4 17 5.3 0.1 4.3 4 0 0 4 4 4 0 SOCS box Beta_helix PF13229.1 KEG13596.1 - 8.5e-85 282.3 126.1 3.3e-15 56.1 13.6 17.3 10 5 4 15 15 15 12 Right handed beta helix region NosD PF05048.8 KEG13596.1 - 5.6e-64 215.5 61.8 2.3e-11 43.2 5.6 14.6 9 5 6 15 15 15 12 Periplasmic copper-binding protein (NosD) RNA12 PF10443.4 KEG13596.1 - 1.2 7.5 0.1 2.2 6.7 0.1 1.3 1 0 0 1 1 1 0 RNA12 protein Glutaredoxin PF00462.19 KEG13597.1 - 1.1e-15 57.2 0.0 1.5e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.1 KEG13597.1 - 1.2e-05 25.0 0.0 1.5e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_4 PF13462.1 KEG13597.1 - 0.00062 19.8 0.1 0.64 9.9 0.1 2.1 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 KEG13597.1 - 0.00085 19.5 0.1 0.002 18.2 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain GST_N_3 PF13417.1 KEG13597.1 - 0.00092 19.3 0.0 0.0011 19.1 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain AhpC-TSA PF00578.16 KEG13597.1 - 0.0079 15.8 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family DSBA PF01323.15 KEG13597.1 - 0.012 15.2 0.1 1.8 8.0 0.1 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain DUF836 PF05768.9 KEG13597.1 - 0.027 14.7 0.0 0.034 14.3 0.0 1.2 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) GST_N_2 PF13409.1 KEG13597.1 - 0.14 12.1 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Redoxin PF08534.5 KEG13597.1 - 0.15 11.5 0.1 0.31 10.5 0.0 1.7 2 1 0 2 2 2 0 Redoxin SET PF00856.23 KEG13598.1 - 7.9e-09 36.0 0.3 5.9e-08 33.1 0.0 2.5 2 0 0 2 2 2 1 SET domain F-box-like PF12937.2 KEG13599.1 - 0.002 17.8 1.9 0.0078 15.9 1.3 2.1 1 0 0 1 1 1 1 F-box-like DUF2975 PF11188.3 KEG13599.1 - 0.0044 16.7 0.8 0.0044 16.7 0.5 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF2975) MgtE_N PF03448.12 KEG13600.1 - 0.16 12.3 0.5 0.42 10.9 0.4 1.6 1 0 0 1 1 1 0 MgtE intracellular N domain Flagellar_rod PF05149.7 KEG13605.1 - 1.4e-87 293.5 18.7 1.4e-87 293.5 12.9 1.9 3 0 0 3 3 3 1 Paraflagellar rod protein Baculo_PEP_C PF04513.7 KEG13605.1 - 0.0016 18.2 4.3 9.8 5.9 0.0 4.4 3 2 1 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus Erp_C PF06780.6 KEG13605.1 - 0.0066 16.3 2.9 0.0066 16.3 2.0 3.3 3 1 0 3 3 3 1 Erp protein C-terminus TPR_1 PF00515.23 KEG13605.1 - 0.36 10.5 1.9 0.51 10.0 0.4 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat NYAP_C PF15452.1 KEG13605.1 - 0.4 9.6 2.5 0.65 8.9 1.7 1.3 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter PAS_10 PF13596.1 KEG13605.1 - 0.46 10.7 4.1 7 6.9 0.3 4.0 5 0 0 5 5 5 0 PAS domain Peptidase_C97 PF05903.9 KEG13608.1 - 7.7e-24 84.1 0.1 2.1e-23 82.7 0.0 1.6 2 0 0 2 2 2 1 PPPDE putative peptidase domain Kelch_4 PF13418.1 KEG13609.1 - 3.7e-30 103.4 0.1 2.8e-07 30.1 0.0 6.2 5 1 0 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.1 KEG13609.1 - 2.8e-23 81.4 1.7 3.3e-06 27.0 0.0 7.0 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_1 PF01344.20 KEG13609.1 - 7e-19 67.1 0.9 1.7e-05 24.2 0.1 6.0 6 1 0 6 6 6 4 Kelch motif Kelch_5 PF13854.1 KEG13609.1 - 1.4e-17 63.2 0.7 0.0069 16.3 0.0 7.0 7 0 0 7 7 7 4 Kelch motif Kelch_6 PF13964.1 KEG13609.1 - 6.6e-13 48.2 8.5 0.00019 21.4 0.0 5.8 4 2 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 KEG13609.1 - 1.4e-09 37.3 12.5 0.0059 16.3 0.0 6.3 6 1 0 6 6 6 3 Kelch motif Lycopene_cycl PF05834.7 KEG13610.1 - 0.012 14.5 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein DZR PF12773.2 KEG13610.1 - 0.11 12.3 4.8 0.76 9.6 0.1 3.2 2 2 0 2 2 2 0 Double zinc ribbon RNHCP PF12647.2 KEG13610.1 - 0.15 11.8 3.0 6.2 6.7 0.0 3.3 2 1 1 3 3 3 0 RNHCP domain DUF3716 PF12511.3 KEG13610.1 - 0.18 11.4 3.1 2 8.0 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3716) DUF2296 PF10058.4 KEG13610.1 - 0.42 10.3 7.0 15 5.4 0.2 3.6 4 0 0 4 4 4 0 Predicted integral membrane metal-binding protein (DUF2296) Zn_Tnp_IS1595 PF12760.2 KEG13610.1 - 7.6 6.4 10.2 28 4.6 0.0 3.9 4 0 0 4 4 4 0 Transposase zinc-ribbon domain Mito_carr PF00153.22 KEG13611.1 - 1.3e-47 159.4 1.0 6.1e-16 57.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_C97 PF05903.9 KEG13613.1 - 2.2e-21 76.2 0.0 3.4e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain Armet PF10208.4 KEG13613.1 - 0.0023 17.5 0.0 0.0041 16.7 0.0 1.3 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding Peptidase_C97 PF05903.9 KEG13615.1 - 1.9e-13 50.4 0.0 3e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain AAA PF00004.24 KEG13617.1 - 3.4e-36 124.3 0.0 5.2e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KEG13617.1 - 1e-05 24.7 0.0 1.8e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KEG13617.1 - 1.2e-05 25.5 0.1 0.00023 21.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain Vps4_C PF09336.5 KEG13617.1 - 3.4e-05 23.6 0.0 0.00011 21.9 0.0 1.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain TIP49 PF06068.8 KEG13617.1 - 0.00078 18.2 0.0 0.0012 17.5 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 KEG13617.1 - 0.001 18.4 0.1 0.0024 17.3 0.1 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 KEG13617.1 - 0.002 17.8 0.1 0.0062 16.2 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 KEG13617.1 - 0.0028 18.4 0.0 0.0072 17.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KEG13617.1 - 0.0044 17.3 0.0 0.0089 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEG13617.1 - 0.0058 16.6 0.0 0.016 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 KEG13617.1 - 0.0061 16.4 0.0 0.019 14.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 KEG13617.1 - 0.0066 15.8 0.3 0.28 10.5 0.2 2.3 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 KEG13617.1 - 0.0076 15.9 0.1 0.018 14.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KEG13617.1 - 0.012 14.7 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 KEG13617.1 - 0.017 14.7 0.1 0.044 13.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KEG13617.1 - 0.028 14.6 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_2 PF07724.9 KEG13617.1 - 0.042 13.7 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 KEG13617.1 - 0.046 13.6 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain LisH PF08513.6 KEG13617.1 - 0.048 13.4 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 LisH PhoH PF02562.11 KEG13617.1 - 0.056 12.6 0.1 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.1 KEG13617.1 - 0.057 13.3 0.1 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KEG13617.1 - 0.063 12.3 0.1 1.2 8.1 0.0 2.2 1 1 1 2 2 2 0 KaiC Actin PF00022.14 KEG13618.1 - 1.3e-118 395.9 0.0 1.4e-118 395.7 0.0 1.0 1 0 0 1 1 1 1 Actin TRM PF02005.11 KEG13619.1 - 1e-100 337.3 0.4 2.2e-73 247.3 0.2 3.0 1 1 1 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Glyco_transf_25 PF01755.12 KEG13620.1 - 7.2e-17 61.6 0.0 5e-14 52.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Myb_DNA-bind_6 PF13921.1 KEG13621.1 - 0.011 15.8 0.4 0.27 11.3 0.0 2.7 2 0 0 2 2 2 0 Myb-like DNA-binding domain Ax_dynein_light PF10211.4 KEG13621.1 - 0.027 14.3 0.0 0.027 14.3 0.0 3.8 3 0 0 3 3 3 0 Axonemal dynein light chain LRR_6 PF13516.1 KEG13622.1 - 1.3e-07 30.9 0.1 0.0044 16.9 0.0 3.4 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.2 KEG13622.1 - 4.4e-07 29.3 0.2 8.5e-05 22.0 0.0 2.5 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEG13622.1 - 0.0037 17.0 0.2 2 8.7 0.1 3.2 2 0 0 2 2 2 1 Leucine Rich Repeat LRR_8 PF13855.1 KEG13622.1 - 0.0041 16.8 0.3 0.078 12.7 0.1 2.4 1 1 1 2 2 2 1 Leucine rich repeat LRR_7 PF13504.1 KEG13622.1 - 0.029 14.5 0.8 26 5.6 0.0 3.7 3 0 0 3 3 3 0 Leucine rich repeat Patatin PF01734.17 KEG13624.1 - 0.013 15.4 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Patatin-like phospholipase Plasmodium_Vir PF05795.6 KEG13625.1 - 0.43 9.7 0.8 0.68 9.0 0.5 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF966 PF06136.8 KEG13625.1 - 2.2 7.5 6.7 0.93 8.8 3.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF966) Kelch_4 PF13418.1 KEG13626.1 - 4.8e-22 77.4 2.2 7.7e-06 25.5 0.0 6.5 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_3 PF13415.1 KEG13626.1 - 1.3e-13 50.7 14.9 5.4e-05 23.2 0.1 8.1 9 1 0 9 9 9 4 Galactose oxidase, central domain Kelch_6 PF13964.1 KEG13626.1 - 5.4e-13 48.4 4.1 0.00042 20.3 0.1 7.0 7 0 0 7 7 7 2 Kelch motif Kelch_1 PF01344.20 KEG13626.1 - 1.4e-12 46.9 8.6 0.012 15.1 0.0 6.2 6 1 0 6 6 6 4 Kelch motif Kelch_5 PF13854.1 KEG13626.1 - 1.1e-11 44.4 16.5 0.012 15.5 0.2 6.1 6 0 0 6 6 6 4 Kelch motif BTB_2 PF02214.17 KEG13626.1 - 1e-08 35.2 0.5 3.4e-06 27.1 0.1 2.6 2 0 0 2 2 2 2 BTB/POZ domain Kelch_2 PF07646.10 KEG13626.1 - 5.9e-08 32.1 5.6 0.22 11.3 0.0 6.2 6 0 0 6 6 6 2 Kelch motif Peptidase_M16_C PF05193.16 KEG13628.1 - 1.4e-09 37.9 0.0 3e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KEG13628.1 - 2.2e-08 33.9 0.1 3.6e-07 30.0 0.0 2.4 1 1 0 1 1 1 1 Insulinase (Peptidase family M16) PDZ PF00595.19 KEG13631.1 - 0.00069 19.7 0.0 0.0059 16.7 0.0 2.3 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KEG13631.1 - 0.00074 19.3 0.0 0.002 17.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain DUF4051 PF13260.1 KEG13631.1 - 0.095 12.0 0.6 1 8.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) PIF1 PF05970.9 KEG13632.1 - 2.9e-36 125.1 0.8 8.2e-29 100.6 0.3 3.5 2 1 1 3 3 3 3 PIF1-like helicase AAA_30 PF13604.1 KEG13632.1 - 6.5e-18 65.0 0.0 1.3e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KEG13632.1 - 1.3e-05 25.3 0.0 9.3e-05 22.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEG13632.1 - 0.00025 20.7 1.6 0.00098 18.8 1.1 2.0 1 0 0 1 1 1 1 Part of AAA domain Herpes_Helicase PF02689.9 KEG13632.1 - 0.00078 17.3 0.4 0.19 9.4 0.0 3.0 4 0 0 4 4 4 2 Helicase AAA_5 PF07728.9 KEG13632.1 - 0.0026 17.4 0.1 0.019 14.6 0.1 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) UvrD_C_2 PF13538.1 KEG13632.1 - 0.016 15.3 0.0 0.16 12.1 0.0 2.6 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain PhoH PF02562.11 KEG13632.1 - 0.022 13.9 0.0 0.055 12.6 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA PF00004.24 KEG13632.1 - 0.037 14.2 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 KEG13632.1 - 0.044 13.3 0.1 0.15 11.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KEG13632.1 - 0.059 13.6 0.2 0.2 11.9 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_17 PF13207.1 KEG13632.1 - 0.081 13.7 0.2 4.9 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.9 KEG13633.1 - 3.5e-36 124.9 2.5 3.3e-29 101.9 0.2 3.3 2 1 1 3 3 3 3 PIF1-like helicase AAA_30 PF13604.1 KEG13633.1 - 2.6e-16 59.7 0.0 4.9e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KEG13633.1 - 0.00011 22.4 0.6 0.0012 19.0 0.2 2.8 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KEG13633.1 - 0.0007 19.2 0.5 0.43 10.0 0.0 3.1 2 1 1 3 3 3 2 AAA domain Viral_helicase1 PF01443.13 KEG13633.1 - 0.00093 18.7 0.6 0.75 9.2 0.0 3.3 2 2 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Herpes_Helicase PF02689.9 KEG13633.1 - 0.0015 16.4 1.0 0.22 9.2 0.0 2.9 2 1 0 3 3 3 2 Helicase AAA_19 PF13245.1 KEG13633.1 - 0.0026 17.4 2.1 0.0056 16.3 0.5 2.3 2 0 0 2 2 2 1 Part of AAA domain IstB_IS21 PF01695.12 KEG13633.1 - 0.0063 15.9 0.3 0.019 14.4 0.2 1.7 1 1 0 1 1 1 1 IstB-like ATP binding protein UvrD_C_2 PF13538.1 KEG13633.1 - 0.029 14.5 0.0 0.12 12.5 0.0 2.1 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_5 PF07728.9 KEG13633.1 - 0.064 12.9 0.4 0.31 10.7 0.2 2.3 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF3074 PF11274.3 KEG13634.1 - 0.021 14.4 0.2 0.056 13.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3074) Sec20 PF03908.8 KEG13636.1 - 2.6e-07 30.2 1.4 2.6e-07 30.2 0.9 1.7 2 1 0 2 2 2 1 Sec20 WD40 PF00400.27 KEG13639.1 - 4.1e-23 80.3 17.5 6.3e-05 22.6 0.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 KEG13639.1 - 0.0037 15.4 2.9 0.43 8.6 0.1 2.5 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Atg14 PF10186.4 KEG13639.1 - 0.79 8.6 26.1 82 1.9 18.1 2.2 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 KEG13639.1 - 5.3 6.5 27.6 2.2 7.8 7.1 2.2 1 1 1 2 2 2 0 IncA protein TMF_TATA_bd PF12325.3 KEG13639.1 - 7.4 6.3 30.3 7.9 6.2 1.4 3.4 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding FAD_binding_6 PF00970.19 KEG13640.1 - 3.4e-07 30.2 0.0 5.6e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KEG13640.1 - 6.4e-05 23.4 0.0 0.00022 21.7 0.0 1.9 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain PEPCK_ATP PF01293.15 KEG13641.1 - 0.2 10.1 0.0 0.33 9.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase Pkinase PF00069.20 KEG13642.1 - 5.1e-52 176.6 0.0 1.1e-51 175.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG13642.1 - 4.6e-28 97.9 0.0 6.9e-27 94.1 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG13642.1 - 0.00013 21.0 0.2 0.0029 16.6 0.2 2.2 1 1 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 KEG13642.1 - 0.02 14.2 0.0 0.066 12.5 0.0 1.9 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL YukC PF10140.4 KEG13642.1 - 0.056 12.0 0.1 0.11 11.0 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC APH PF01636.18 KEG13642.1 - 0.057 13.1 0.1 0.47 10.1 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family NAD_binding_2 PF03446.10 KEG13646.1 - 1.3e-31 109.5 0.1 1.3e-31 109.5 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KEG13646.1 - 8.3e-14 51.7 0.9 1.4e-12 47.7 0.6 2.3 1 1 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 3HCDH_N PF02737.13 KEG13646.1 - 0.064 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Minor_capsid_1 PF10665.4 KEG13646.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Minor capsid protein SecE PF00584.15 KEG13647.1 - 6.3e-12 44.8 0.2 7.4e-12 44.6 0.1 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex 2OG-FeII_Oxy PF03171.15 KEG13648.1 - 1e-12 48.2 0.0 2e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KEG13648.1 - 0.013 15.9 0.0 1.2 9.7 0.0 2.6 3 0 0 3 3 3 0 non-haem dioxygenase in morphine synthesis N-terminal AMPKBI PF04739.10 KEG13649.1 - 0.052 13.4 0.9 0.4 10.5 0.0 2.3 2 0 0 2 2 2 0 5'-AMP-activated protein kinase beta subunit, interation domain Complex1_LYR PF05347.10 KEG13650.1 - 7.8e-07 28.8 0.1 2e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KEG13650.1 - 6.2e-06 26.3 0.1 3.3e-05 24.0 0.0 2.1 2 1 0 2 2 2 1 Complex1_LYR-like Dynein_heavy PF03028.10 KEG13651.1 - 9.4e-170 566.0 1.0 5.1e-104 348.7 0.0 3.0 3 0 0 3 3 3 2 Dynein heavy chain and region D6 of dynein motor DHC_N1 PF08385.7 KEG13651.1 - 7.1e-146 486.9 2.1 7.1e-146 486.9 1.4 5.2 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 KEG13651.1 - 1.1e-119 399.6 5.1 1.1e-119 399.6 3.6 3.7 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 KEG13651.1 - 1.3e-91 306.1 0.0 2.7e-91 305.1 0.0 1.5 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 KEG13651.1 - 3.5e-71 239.3 0.1 7.9e-71 238.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 KEG13651.1 - 1.3e-54 184.5 0.7 3.1e-54 183.2 0.5 1.7 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_7 PF12775.2 KEG13651.1 - 2.5e-42 144.8 0.1 1.6e-41 142.2 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 MT PF12777.2 KEG13651.1 - 3.7e-40 137.7 5.0 8.9e-40 136.4 3.5 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 KEG13651.1 - 1.2e-15 57.4 0.1 0.00037 20.2 0.0 6.0 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA PF00004.24 KEG13651.1 - 1.1e-06 28.9 0.1 0.026 14.7 0.0 5.1 5 0 0 5 5 5 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEG13651.1 - 1.7e-06 28.1 1.6 1.2 9.1 0.0 5.7 6 0 0 6 6 6 2 AAA ATPase domain AAA_22 PF13401.1 KEG13651.1 - 2.8e-05 24.2 0.0 3.7 7.7 0.0 4.7 4 0 0 4 4 3 2 AAA domain AAA_17 PF13207.1 KEG13651.1 - 0.0055 17.5 0.5 0.16 12.8 0.0 4.0 3 0 0 3 3 2 1 AAA domain LPP PF04728.8 KEG13651.1 - 0.22 11.3 4.0 2.3 8.0 0.8 3.0 2 0 0 2 2 2 0 Lipoprotein leucine-zipper EF-hand_6 PF13405.1 KEG13652.1 - 1.4e-09 37.0 0.1 0.012 15.3 0.0 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 KEG13652.1 - 9.9e-07 28.8 0.1 1.4 9.0 0.0 4.3 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.27 KEG13652.1 - 1.5e-06 27.1 0.0 0.17 11.2 0.0 3.7 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 KEG13652.1 - 0.00067 19.2 0.0 1.4 8.5 0.0 3.8 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.1 KEG13652.1 - 0.0012 18.1 0.0 0.55 9.6 0.0 3.3 3 0 0 3 3 3 1 EF hand HTH_11 PF08279.7 KEG13652.1 - 0.014 15.0 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 HTH domain Adeno_E3 PF06040.6 KEG13652.1 - 0.3 11.0 1.0 4.6 7.2 0.0 2.6 2 0 0 2 2 2 0 Adenovirus E3 protein Tubulin PF00091.20 KEG13653.1 - 2.1e-71 240.1 0.0 3e-71 239.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KEG13653.1 - 5.1e-45 152.5 0.2 5.1e-45 152.5 0.1 1.9 3 0 0 3 3 3 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KEG13653.1 - 1.3e-05 25.2 0.0 5.2e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain PUB PF09409.5 KEG13654.1 - 2.3e-11 43.2 0.0 3.9e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 PUB domain Mac PF12464.3 KEG13654.1 - 0.00051 20.0 0.0 0.55 10.3 0.1 2.6 2 0 0 2 2 2 2 Maltose acetyltransferase Ank_2 PF12796.2 KEG13656.1 - 1.9e-25 89.0 0.1 3.4e-12 46.5 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KEG13656.1 - 5.4e-24 82.7 2.5 4.1e-06 26.3 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 KEG13656.1 - 3.4e-20 71.6 5.7 2.8e-11 43.2 0.0 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEG13656.1 - 1.7e-19 67.9 1.6 0.00025 20.9 0.0 5.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 KEG13656.1 - 4.1e-18 65.3 2.5 2.2e-11 43.9 0.0 3.4 2 1 0 3 3 3 2 Ankyrin repeats (many copies) SLBP_RNA_bind PF15247.1 KEG13657.1 - 2.3e-15 56.1 0.0 5.7e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain Methyltransf_23 PF13489.1 KEG13659.1 - 2.2e-22 79.5 0.0 3.3e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEG13659.1 - 5.1e-18 65.0 0.0 1.3e-17 63.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEG13659.1 - 2.5e-16 59.9 0.1 5.5e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEG13659.1 - 2.4e-13 50.3 0.1 7.5e-13 48.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEG13659.1 - 2.7e-12 47.2 0.1 4.6e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KEG13659.1 - 3.5e-10 39.4 0.0 6.7e-10 38.4 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 KEG13659.1 - 1.9e-08 34.3 0.0 4.3e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KEG13659.1 - 4.9e-08 32.4 0.0 7.2e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.6 KEG13659.1 - 9.5e-07 28.4 0.1 1.1e-05 24.9 0.1 2.0 1 1 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_25 PF13649.1 KEG13659.1 - 1.9e-06 28.1 0.2 5.1e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 KEG13659.1 - 6.5e-06 25.8 0.1 1.1e-05 25.0 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain TehB PF03848.9 KEG13659.1 - 1.4e-05 24.3 0.0 5.4e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 Tellurite resistance protein TehB Ubie_methyltran PF01209.13 KEG13659.1 - 5.1e-05 22.4 0.0 8.5e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Pox_MCEL PF03291.11 KEG13659.1 - 0.0001 21.2 0.0 0.00016 20.6 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme MTS PF05175.9 KEG13659.1 - 0.00021 20.7 0.1 0.00048 19.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain DREV PF05219.7 KEG13659.1 - 0.00047 19.1 0.0 0.0013 17.6 0.0 1.6 1 1 0 1 1 1 1 DREV methyltransferase PCMT PF01135.14 KEG13659.1 - 0.0005 19.6 0.1 0.00086 18.8 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 KEG13659.1 - 0.0039 16.5 0.4 0.0084 15.5 0.3 1.6 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW TPMT PF05724.6 KEG13659.1 - 0.0072 15.7 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) RrnaAD PF00398.15 KEG13659.1 - 0.072 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FYVE PF01363.16 KEG13660.1 - 5.6e-17 61.4 13.4 2.7e-15 56.0 5.6 2.7 2 0 0 2 2 2 2 FYVE zinc finger SOBP PF15279.1 KEG13660.1 - 0.32 11.3 12.9 0.45 10.8 8.9 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein PhnA_Zn_Ribbon PF08274.7 KEG13660.1 - 0.59 9.9 0.1 0.59 9.9 0.1 3.9 4 0 0 4 4 4 0 PhnA Zinc-Ribbon Asp-B-Hydro_N PF05279.6 KEG13660.1 - 6.7 6.4 36.8 8.7 6.1 25.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SKG6 PF08693.5 KEG13661.1 - 0.032 13.5 2.8 0.032 13.5 2.0 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain GAS PF13851.1 KEG13662.1 - 0.003 16.7 10.0 0.003 16.7 7.0 4.1 2 1 2 4 4 4 2 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.7 KEG13662.1 - 0.0031 17.3 2.2 0.0031 17.3 1.5 3.9 1 1 2 4 4 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4201 PF13870.1 KEG13662.1 - 0.065 12.6 48.2 0.25 10.7 19.5 3.3 2 2 1 3 3 3 0 Domain of unknown function (DUF4201) Reo_sigmaC PF04582.7 KEG13662.1 - 0.66 9.0 21.2 0.29 10.2 1.9 4.0 1 1 3 4 4 4 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 KEG13662.1 - 1.1 9.1 55.1 0.36 10.6 10.5 3.8 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.6 KEG13662.1 - 6.7 6.4 57.9 0.94 9.2 15.4 3.9 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) TctB PF07331.6 KEG13665.1 - 0.22 11.1 6.9 0.56 9.8 4.8 1.6 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DUF4328 PF14219.1 KEG13665.1 - 2.8 7.1 6.8 0.59 9.4 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4328) Sugarporin_N PF11471.3 KEG13665.1 - 2.9 7.5 4.5 27 4.4 0.8 2.3 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Hydrolase_6 PF13344.1 KEG13666.1 - 2.6e-20 72.1 0.0 5e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KEG13666.1 - 3e-12 46.0 0.0 6.5e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Metallophos PF00149.23 KEG13666.1 - 0.15 11.4 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase DUF4121 PF13497.1 KEG13666.1 - 0.22 10.5 0.0 0.36 9.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) PIH1 PF08190.7 KEG13667.1 - 4.3e-103 345.2 0.2 4.3e-103 345.2 0.1 1.8 3 0 0 3 3 3 1 pre-RNA processing PIH1/Nop17 DUF2229 PF09989.4 KEG13667.1 - 8.6 5.7 6.5 6.4 6.1 2.1 2.2 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) PGAP1 PF07819.8 KEG13669.1 - 1.6e-11 44.2 0.0 1e-05 25.2 0.0 2.4 2 0 0 2 2 2 2 PGAP1-like protein Abhydrolase_6 PF12697.2 KEG13669.1 - 2.2e-05 24.4 1.2 0.00011 22.1 0.1 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEG13669.1 - 0.0057 16.4 0.0 0.53 10.0 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family UPF0154 PF03672.8 KEG13669.1 - 0.11 12.1 0.0 0.31 10.6 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) DUF1744 PF08490.7 KEG13670.1 - 1.7e-47 161.8 0.1 3.2e-46 157.6 0.0 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 KEG13670.1 - 5e-46 157.0 0.2 8.6e-46 156.2 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 KEG13670.1 - 2.4e-18 66.2 0.4 1e-14 54.2 0.0 4.2 3 1 0 3 3 3 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 KEG13670.1 - 1.8e-10 40.6 0.2 1.2e-06 28.2 0.0 3.4 3 0 0 3 3 3 2 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 KEG13670.1 - 1.6e-07 31.2 0.1 8.2e-07 28.9 0.0 2.2 2 1 0 2 2 2 1 RNase_H superfamily zf-3CxxC PF13695.1 KEG13671.1 - 1.1e-08 35.1 1.1 1.4e-08 34.8 0.8 1.2 1 0 0 1 1 1 1 Zinc-binding domain zf-DNA_Pol PF08996.5 KEG13671.1 - 0.073 12.4 0.3 0.093 12.0 0.2 1.1 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger FdhE PF04216.7 KEG13671.1 - 0.14 11.8 0.2 0.18 11.4 0.1 1.1 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation RRN7 PF11781.3 KEG13671.1 - 0.25 10.8 3.2 6.4 6.3 0.3 2.2 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zinc_ribbon_5 PF13719.1 KEG13671.1 - 0.44 10.1 4.9 0.86 9.2 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KEG13671.1 - 0.47 10.1 4.9 0.61 9.8 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-C3HC4_3 PF13920.1 KEG13672.1 - 9.8e-09 34.7 4.2 1.7e-08 34.0 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEG13672.1 - 6.9e-08 32.2 8.1 1.3e-07 31.3 5.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KEG13672.1 - 7.4e-07 29.0 7.3 1.4e-06 28.2 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEG13672.1 - 4.2e-06 26.3 3.2 7.6e-06 25.4 2.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEG13672.1 - 1.4e-05 24.6 3.3 2.7e-05 23.8 2.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 KEG13672.1 - 0.00084 18.8 2.2 0.0016 17.9 1.5 1.5 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 KEG13672.1 - 0.0098 15.7 4.0 0.022 14.6 2.8 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING NfeD PF01957.13 KEG13672.1 - 0.1 12.7 0.9 0.17 12.0 0.7 1.3 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding zf-RING_UBOX PF13445.1 KEG13672.1 - 0.11 12.2 2.1 0.26 11.0 1.4 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Rtf2 PF04641.7 KEG13672.1 - 0.21 10.7 0.1 0.37 9.9 0.1 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger zf-rbx1 PF12678.2 KEG13672.1 - 3.5 7.8 8.7 0.73 9.9 3.1 2.0 2 1 0 2 2 2 0 RING-H2 zinc finger LisH PF08513.6 KEG13673.1 - 0.00025 20.6 0.2 0.00041 20.0 0.1 1.3 1 0 0 1 1 1 1 LisH 14-3-3 PF00244.15 KEG13675.1 - 8.3e-97 322.8 4.2 9.6e-97 322.6 2.9 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 KEG13675.1 - 0.00077 19.3 2.0 0.036 13.9 0.5 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEG13675.1 - 0.0017 17.9 2.2 3.4 7.6 0.6 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEG13675.1 - 0.0065 16.3 2.6 0.68 9.9 0.2 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 KEG13675.1 - 0.0083 15.7 0.7 0.037 13.6 0.1 2.3 2 1 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 KEG13675.1 - 0.059 13.0 2.2 0.34 10.6 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat CofC PF01983.11 KEG13675.1 - 0.098 11.6 0.3 0.17 10.7 0.2 1.4 1 0 0 1 1 1 0 Guanylyl transferase CofC like OPA3 PF07047.7 KEG13676.1 - 0.0032 17.2 0.0 0.0039 16.9 0.0 1.1 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) DUF2567 PF10821.3 KEG13676.1 - 0.016 14.7 2.1 0.02 14.4 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2567) OPA3 PF07047.7 KEG13677.1 - 1.6e-08 34.4 0.1 1.8e-08 34.1 0.1 1.1 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) T2SM PF04612.7 KEG13677.1 - 0.028 14.2 0.2 0.035 13.8 0.1 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Baculo_PEP_C PF04513.7 KEG13677.1 - 0.032 14.0 0.1 0.04 13.7 0.1 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3373 PF11853.3 KEG13677.1 - 0.15 10.5 0.1 0.17 10.4 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF2779 PF11074.3 KEG13680.1 - 1.7e-44 150.9 0.0 2.9e-44 150.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function(DUF2779) Peptidase_M17_N PF02789.12 KEG13681.1 - 0.15 11.7 3.3 0.14 11.8 0.7 2.1 2 1 1 3 3 3 0 Cytosol aminopeptidase family, N-terminal domain TTL PF03133.10 KEG13682.1 - 1.5e-68 230.8 0.1 2.4e-68 230.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 KEG13682.1 - 1.2e-06 27.5 0.8 0.00016 20.5 0.0 3.7 3 1 1 4 4 4 1 YheC/D like ATP-grasp ATP-grasp_3 PF02655.9 KEG13682.1 - 0.094 12.5 0.0 0.45 10.3 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp domain ATP-grasp_4 PF13535.1 KEG13682.1 - 0.11 12.1 0.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp domain BOP1NT PF08145.7 KEG13684.1 - 4.2e-85 285.6 7.0 6.1e-85 285.0 4.8 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 KEG13684.1 - 3e-24 83.9 0.5 1.7e-10 40.3 0.0 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat BpuJI_N PF11564.3 KEG13684.1 - 0.0075 15.2 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease BpuJI - N terminal RCC1 PF00415.13 KEG13686.1 - 4.5e-32 110.0 17.9 7.3e-15 54.9 0.0 7.5 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KEG13686.1 - 2.6e-14 52.3 11.0 0.00016 21.1 0.2 5.6 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat LRR_4 PF12799.2 KEG13688.1 - 2.2e-14 52.6 6.2 0.0009 18.8 0.1 4.8 2 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG13688.1 - 9.9e-10 38.0 8.3 0.0015 18.2 0.0 4.1 4 0 0 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 KEG13688.1 - 4.2e-07 29.1 6.4 9 6.7 0.1 8.0 8 1 0 8 8 8 2 Leucine Rich Repeat LRR_7 PF13504.1 KEG13688.1 - 3e-06 26.5 1.8 10 6.8 0.0 6.5 7 0 0 7 7 7 1 Leucine rich repeat LRR_6 PF13516.1 KEG13688.1 - 1e-05 25.1 4.7 4.3 7.7 0.1 6.5 4 2 2 6 6 6 2 Leucine Rich repeat LRR_9 PF14580.1 KEG13688.1 - 2.3e-05 24.0 0.1 0.0018 17.8 0.0 2.4 1 1 1 2 2 2 1 Leucine-rich repeat DUF904 PF06005.7 KEG13688.1 - 0.038 14.2 0.7 0.095 13.0 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF904) WD40 PF00400.27 KEG13689.1 - 0.00012 21.7 10.7 0.0023 17.7 0.1 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat tRNA-synt_1f PF01921.13 KEG13689.1 - 0.012 14.3 0.2 0.021 13.4 0.1 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (K) DNA_ligase_A_M PF01068.16 KEG13690.1 - 1.4e-07 31.0 0.0 0.0051 16.2 0.0 2.4 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_OB_2 PF14743.1 KEG13690.1 - 0.03 13.9 0.1 0.071 12.8 0.0 1.6 1 0 0 1 1 1 0 DNA ligase OB-like domain PUF PF00806.14 KEG13691.1 - 4.1e-14 51.1 0.4 2.3 7.8 0.0 8.9 9 0 0 9 9 9 6 Pumilio-family RNA binding repeat DUF2087 PF09860.4 KEG13691.1 - 0.077 12.7 0.0 0.24 11.1 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2087) Snapin_Pallidin PF14712.1 KEG13692.1 - 0.012 15.8 0.0 0.015 15.5 0.0 1.2 1 0 0 1 1 1 0 Snapin/Pallidin Cortex-I_coil PF09304.5 KEG13692.1 - 0.019 14.9 0.4 0.023 14.7 0.3 1.2 1 0 0 1 1 1 0 Cortexillin I, coiled coil DUF2559 PF10832.3 KEG13692.1 - 0.019 14.7 2.3 0.29 10.9 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2559) APH PF01636.18 KEG13692.1 - 0.043 13.5 1.1 0.044 13.5 0.8 1.0 1 0 0 1 1 1 0 Phosphotransferase enzyme family HTH_AsnC-type PF13404.1 KEG13692.1 - 0.088 12.3 3.0 0.27 10.7 0.0 2.4 2 1 0 2 2 2 0 AsnC-type helix-turn-helix domain Peptidase_M32 PF02074.10 KEG13693.1 - 4.1e-28 98.2 0.0 4.5e-28 98.1 0.0 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase Peptidase_M32 PF02074.10 KEG13694.1 - 1.7e-135 452.4 0.1 2e-135 452.2 0.1 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase Kinesin PF00225.18 KEG13695.1 - 2.3e-101 338.8 0.0 3e-101 338.4 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain FHA PF00498.21 KEG13695.1 - 2.4e-05 24.3 0.0 7.5e-05 22.7 0.0 1.9 1 0 0 1 1 1 1 FHA domain Ras PF00071.17 KEG13695.1 - 5.1e-05 22.7 0.0 0.0006 19.2 0.0 2.6 3 0 0 3 3 3 1 Ras family Miro PF08477.8 KEG13695.1 - 0.015 15.7 0.0 0.087 13.3 0.0 2.3 2 0 0 2 2 2 0 Miro-like protein AAA_29 PF13555.1 KEG13695.1 - 0.032 13.7 0.1 1.4 8.5 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain Rnk_N PF14760.1 KEG13695.1 - 0.051 13.6 0.1 0.16 12.0 0.1 1.9 1 0 0 1 1 1 0 Rnk N-terminus AAA_22 PF13401.1 KEG13695.1 - 0.055 13.6 0.1 14 5.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 KEG13695.1 - 0.075 13.0 0.0 8.2 6.4 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Peptidase_M17 PF00883.16 KEG13696.1 - 3.3e-85 285.6 0.0 4.4e-85 285.2 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Frag1 PF10277.4 KEG13698.1 - 7.4e-34 117.0 12.3 7.4e-34 117.0 8.6 3.7 3 1 1 4 4 4 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.18 KEG13698.1 - 0.023 14.6 0.0 0.066 13.1 0.0 1.8 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DUF1673 PF07895.6 KEG13698.1 - 0.9 9.0 12.3 1.3 8.5 0.2 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1673) TMEM52 PF14979.1 KEG13699.1 - 9.9e-05 22.2 0.2 0.00017 21.4 0.1 1.3 1 0 0 1 1 1 1 Transmembrane 52 IncA PF04156.9 KEG13699.1 - 0.016 14.7 1.0 0.024 14.2 0.7 1.1 1 0 0 1 1 1 0 IncA protein Shisa PF13908.1 KEG13699.1 - 0.019 15.1 4.4 0.051 13.7 2.4 1.8 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator MLANA PF14991.1 KEG13699.1 - 0.089 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein melan-A Prominin PF05478.6 KEG13699.1 - 0.093 10.2 2.5 0.13 9.8 1.7 1.1 1 0 0 1 1 1 0 Prominin TBCC PF07986.7 KEG13700.1 - 7.3e-30 102.8 0.3 1.3e-29 102.0 0.2 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C DHC_N2 PF08393.8 KEG13701.1 - 2.7e-111 372.0 4.0 2.7e-111 372.0 2.8 5.2 5 1 0 5 5 4 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 KEG13701.1 - 5.2e-109 365.2 0.0 5.2e-109 365.2 0.0 2.7 5 0 0 5 5 3 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 KEG13701.1 - 5.2e-78 261.7 1.0 1.2e-77 260.5 0.0 2.2 3 0 0 3 3 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 KEG13701.1 - 8.3e-40 136.0 0.3 1.9e-39 134.8 0.2 1.7 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 KEG13701.1 - 7.4e-31 107.1 0.7 4.4e-30 104.5 0.0 2.6 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_5 PF07728.9 KEG13701.1 - 1.3e-30 105.9 0.8 2.8e-18 65.9 0.0 6.2 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) MT PF12777.2 KEG13701.1 - 5.6e-30 104.2 9.9 1.1e-29 103.3 6.9 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.2 KEG13701.1 - 3e-23 82.2 0.1 2.4e-22 79.2 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_16 PF13191.1 KEG13701.1 - 3.3e-10 40.2 13.6 0.0051 16.8 0.0 6.8 6 1 0 6 6 5 2 AAA ATPase domain AAA PF00004.24 KEG13701.1 - 5.4e-10 39.5 6.7 0.028 14.6 0.0 6.6 7 0 0 7 7 6 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEG13701.1 - 1.4e-09 38.1 9.8 0.025 14.7 0.0 6.6 6 1 0 6 6 4 2 AAA domain AAA_17 PF13207.1 KEG13701.1 - 2.2e-08 34.9 0.2 3e-05 24.8 0.0 4.2 4 0 0 4 4 2 1 AAA domain AAA_33 PF13671.1 KEG13701.1 - 5.7e-05 23.0 3.8 0.0056 16.5 0.0 4.5 5 0 0 5 5 4 1 AAA domain AAA_19 PF13245.1 KEG13701.1 - 6.1e-05 22.6 0.1 1 9.1 0.0 4.5 4 0 0 4 4 3 1 Part of AAA domain ERM PF00769.14 KEG13701.1 - 6.5e-05 22.5 8.8 6.5e-05 22.5 6.1 4.9 5 0 0 5 5 3 1 Ezrin/radixin/moesin family AAA_14 PF13173.1 KEG13701.1 - 8.3e-05 22.4 0.0 6.6 6.6 0.0 5.1 4 0 0 4 4 4 0 AAA domain DUF258 PF03193.11 KEG13701.1 - 0.0002 20.5 0.0 0.00098 18.3 0.0 2.2 2 0 0 2 2 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KEG13701.1 - 0.0003 20.2 0.1 0.017 14.6 0.0 3.1 3 0 0 3 3 2 1 P-loop containing region of AAA domain RNA_helicase PF00910.17 KEG13701.1 - 0.00036 20.6 0.8 3.2 7.9 0.0 4.7 4 0 0 4 4 4 1 RNA helicase AAA_18 PF13238.1 KEG13701.1 - 0.00063 20.0 0.0 0.00063 20.0 0.0 4.7 6 0 0 6 6 3 1 AAA domain Tropomyosin_1 PF12718.2 KEG13701.1 - 0.0015 18.3 13.7 0.0015 18.3 9.5 4.8 6 0 0 6 6 3 1 Tropomyosin like ABC_tran PF00005.22 KEG13701.1 - 0.0019 18.4 0.0 0.0019 18.4 0.0 4.8 6 0 0 6 6 2 1 ABC transporter AAA_28 PF13521.1 KEG13701.1 - 0.0027 17.6 6.4 0.032 14.1 0.0 5.1 5 0 0 5 5 4 1 AAA domain AAA_21 PF13304.1 KEG13701.1 - 0.0064 16.4 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KEG13701.1 - 0.008 15.6 0.1 1.4 8.2 0.0 4.7 4 0 0 4 4 4 1 AAA-like domain Reo_sigmaC PF04582.7 KEG13701.1 - 0.015 14.5 1.8 4 6.5 0.0 3.1 2 0 0 2 2 2 0 Reovirus sigma C capsid protein MobB PF03205.9 KEG13701.1 - 0.025 14.2 0.0 0.12 12.1 0.0 2.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SMC_N PF02463.14 KEG13701.1 - 2.5 7.2 1.0 52 2.9 0.0 3.4 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain TTL PF03133.10 KEG13702.1 - 1.5e-39 135.6 0.0 2.4e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SPW PF03779.9 KEG13703.1 - 0.15 11.4 1.9 13 5.2 0.0 2.4 2 0 0 2 2 2 0 SPW repeat UQ_con PF00179.21 KEG13705.1 - 1.8e-05 24.2 0.1 3.3e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UQ_con PF00179.21 KEG13706.1 - 1.1e-42 144.7 0.0 1.3e-42 144.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 KEG13706.1 - 0.0033 17.0 0.1 0.0061 16.2 0.0 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 KEG13706.1 - 0.012 15.5 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 0 RWD domain HMG_CoA_synt_N PF01154.12 KEG13708.1 - 1.8e-11 43.8 0.0 3e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.5 KEG13708.1 - 2.9e-07 30.2 0.1 0.0026 17.2 0.0 2.6 3 0 0 3 3 3 2 Hydroxymethylglutaryl-coenzyme A synthase C terminal ACP_syn_III PF08545.5 KEG13708.1 - 0.0012 18.4 0.3 0.0029 17.2 0.2 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF1726 PF08351.6 KEG13708.1 - 0.057 13.1 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1726) Ribosomal_60s PF00428.14 KEG13710.1 - 0.031 14.6 3.9 0.056 13.8 2.7 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Kelch_4 PF13418.1 KEG13711.1 - 2.5e-52 174.4 4.2 1.2e-08 34.5 0.0 6.8 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 KEG13711.1 - 8.2e-51 169.1 7.5 1.5e-09 37.7 0.0 7.3 7 0 0 7 7 7 7 Galactose oxidase, central domain Kelch_1 PF01344.20 KEG13711.1 - 7.2e-39 131.0 11.5 9.6e-08 31.4 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 KEG13711.1 - 4.4e-35 118.3 7.4 3.7e-06 26.8 0.0 6.2 4 2 2 6 6 6 5 Kelch motif Kelch_5 PF13854.1 KEG13711.1 - 1.2e-32 111.2 9.0 8.1e-06 25.6 0.0 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.10 KEG13711.1 - 8.6e-24 82.3 12.8 2.8e-06 26.8 0.0 6.8 6 2 0 6 6 6 5 Kelch motif Rax2 PF12768.2 KEG13711.1 - 0.00053 19.2 0.1 0.13 11.4 0.0 3.0 2 1 1 3 3 3 1 Cortical protein marker for cell polarity RAG2 PF03089.9 KEG13711.1 - 0.043 12.5 1.3 0.31 9.7 0.1 2.8 2 1 0 3 3 3 0 Recombination activating protein 2 Med10 PF09748.4 KEG13711.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex Ribosomal_S8e PF01201.17 KEG13712.1 - 1.2e-42 145.2 3.9 1.4e-42 144.9 2.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e Transketolase_N PF00456.16 KEG13713.1 - 5.6e-136 452.7 0.0 7.5e-136 452.3 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KEG13713.1 - 5.8e-45 152.9 0.0 1e-44 152.1 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KEG13713.1 - 1e-06 28.7 0.0 1.9e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 KEG13713.1 - 0.00018 20.5 0.0 0.018 14.0 0.0 2.3 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 KEG13713.1 - 0.0017 17.1 0.0 0.0026 16.5 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF3584 PF12128.3 KEG13713.1 - 0.33 8.2 0.0 0.44 7.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) KOW PF00467.24 KEG13714.1 - 9.4e-06 25.1 1.1 2e-05 24.1 0.2 2.1 2 1 0 2 2 2 1 KOW motif MutL_C PF08676.6 KEG13715.1 - 2e-27 95.5 0.0 4.1e-27 94.5 0.0 1.5 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 KEG13715.1 - 3.6e-15 55.4 0.0 2.5e-14 52.7 0.0 2.3 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KEG13715.1 - 7.8e-09 35.2 0.8 3.2e-08 33.3 0.6 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KEG13715.1 - 2.5e-06 27.1 0.1 5.7e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DivIC PF04977.10 KEG13716.1 - 0.0014 18.0 0.3 0.0014 18.0 0.2 7.8 6 3 1 7 7 7 1 Septum formation initiator TPMT PF05724.6 KEG13718.1 - 2.1e-21 76.3 0.2 3e-19 69.3 0.0 2.2 2 0 0 2 2 2 2 Thiopurine S-methyltransferase (TPMT) Methyltransf_26 PF13659.1 KEG13718.1 - 0.0064 16.5 0.5 0.012 15.5 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase domain Abi PF02517.11 KEG13719.1 - 0.065 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 CAAX protease self-immunity EF-hand_9 PF14658.1 KEG13720.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain Laminin_G_3 PF13385.1 KEG13721.1 - 1.3e-11 44.9 0.1 2.3e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Aldedh PF00171.17 KEG13723.1 - 8.4e-100 334.2 0.0 1e-99 334.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family zf-CCCH PF00642.19 KEG13724.1 - 7.6e-08 31.8 7.2 0.00029 20.4 1.7 2.8 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCHC PF00098.18 KEG13724.1 - 5.7e-07 29.1 0.5 5.7e-07 29.1 0.3 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.1 KEG13724.1 - 6.2e-06 25.5 1.7 1.1e-05 24.7 1.2 1.4 1 0 0 1 1 1 1 Zinc knuckle RRM_1 PF00076.17 KEG13724.1 - 0.016 14.8 0.0 0.049 13.2 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_4 PF14392.1 KEG13724.1 - 0.1 12.2 1.9 0.3 10.7 1.3 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_3 PF13878.1 KEG13725.1 - 3e-10 39.4 0.6 7.8e-10 38.1 0.4 1.8 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO ABC_tran PF00005.22 KEG13726.1 - 7.1e-47 159.1 1.0 9.4e-22 77.7 0.0 3.7 3 0 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 KEG13726.1 - 2.4e-25 88.1 7.7 2.4e-25 88.1 5.3 3.1 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.1 KEG13726.1 - 1.1e-18 68.2 6.8 1e-05 25.6 0.4 4.5 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 KEG13726.1 - 7.1e-08 31.9 2.9 0.055 12.6 0.0 4.2 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KEG13726.1 - 1.1e-06 28.0 0.1 0.075 12.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KEG13726.1 - 4e-06 27.6 1.9 0.00046 20.9 0.0 3.9 4 1 0 4 4 2 1 AAA domain AAA_33 PF13671.1 KEG13726.1 - 2.9e-05 23.9 1.9 0.23 11.3 0.0 3.8 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 KEG13726.1 - 3.3e-05 23.7 0.2 0.18 11.7 0.0 3.4 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_16 PF13191.1 KEG13726.1 - 3.8e-05 23.7 8.7 0.0048 16.8 0.7 3.0 2 2 1 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 KEG13726.1 - 8.4e-05 21.8 0.0 0.39 9.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_15 PF13175.1 KEG13726.1 - 9.3e-05 21.6 1.5 0.81 8.6 0.0 4.1 3 1 1 4 4 4 1 AAA ATPase domain Miro PF08477.8 KEG13726.1 - 0.00074 20.0 0.0 0.21 12.0 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein SbcCD_C PF13558.1 KEG13726.1 - 0.0023 17.8 0.4 0.27 11.1 0.1 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NACHT PF05729.7 KEG13726.1 - 0.0023 17.6 0.0 0.77 9.3 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA PF00004.24 KEG13726.1 - 0.0032 17.6 0.0 0.42 10.7 0.0 3.6 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 KEG13726.1 - 0.0041 17.4 12.1 0.099 12.9 0.0 4.4 5 0 0 5 5 5 2 AAA domain AAA_30 PF13604.1 KEG13726.1 - 0.0057 16.2 0.0 0.94 9.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KEG13726.1 - 0.0059 16.7 4.1 0.4 10.8 0.1 3.7 3 3 0 3 3 3 1 AAA domain Dynamin_N PF00350.18 KEG13726.1 - 0.006 16.4 1.9 6.9 6.4 0.0 3.9 4 0 0 4 4 4 0 Dynamin family ArgK PF03308.11 KEG13726.1 - 0.0087 14.8 0.6 0.88 8.2 0.0 3.0 3 0 0 3 3 3 1 ArgK protein AAA_28 PF13521.1 KEG13726.1 - 0.0097 15.8 5.3 0.025 14.5 0.0 3.4 4 0 0 4 4 3 1 AAA domain MobB PF03205.9 KEG13726.1 - 0.011 15.3 0.1 1.8 8.2 0.0 3.2 4 0 0 4 4 2 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 KEG13726.1 - 0.017 14.6 0.3 0.065 12.7 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 KEG13726.1 - 0.017 14.5 0.3 2.5 7.5 0.0 2.7 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 KEG13726.1 - 0.023 15.0 0.0 0.023 15.0 0.0 3.6 5 0 0 5 5 4 0 AAA domain AAA_25 PF13481.1 KEG13726.1 - 0.027 13.8 0.0 7.4 5.9 0.0 3.0 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KEG13726.1 - 0.03 13.7 0.0 10 5.5 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATP-synt_ab PF00006.20 KEG13726.1 - 0.038 13.4 0.0 0.13 11.7 0.0 2.0 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain CUE PF02845.11 KEG13726.1 - 0.067 12.7 0.2 1.4 8.5 0.0 3.1 4 0 0 4 4 4 0 CUE domain RNA_helicase PF00910.17 KEG13726.1 - 0.069 13.3 1.9 15 5.8 0.0 3.4 4 0 0 4 4 3 0 RNA helicase AAA_24 PF13479.1 KEG13726.1 - 0.098 12.2 3.0 7.6 6.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.9 KEG13726.1 - 0.11 12.2 0.9 1.9 8.1 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 KEG13726.1 - 0.47 9.8 5.3 2.8 7.2 0.0 3.6 3 1 0 4 4 4 0 AAA-like domain VIT1 PF01988.14 KEG13726.1 - 0.48 9.8 1.3 5.9 6.3 0.1 2.4 2 0 0 2 2 2 0 VIT family PIN PF01850.16 KEG13726.1 - 2.9 8.2 5.5 3.9 7.8 0.0 3.0 3 0 0 3 3 3 0 PIN domain DUF4558 PF15104.1 KEG13727.1 - 2e-05 24.4 2.4 2.4e-05 24.1 1.4 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4558) PaaX_C PF08223.6 KEG13727.1 - 0.1 12.3 0.1 0.13 11.9 0.1 1.1 1 0 0 1 1 1 0 PaaX-like protein C-terminal domain Acetyltransf_1 PF00583.19 KEG13728.1 - 1.6e-11 44.0 0.0 2.6e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEG13728.1 - 3.8e-09 36.5 0.1 7.3e-09 35.6 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KEG13728.1 - 6.8e-05 22.7 0.1 0.00012 21.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KEG13728.1 - 0.017 15.2 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEG13728.1 - 0.026 14.2 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 FR47-like protein GNAT_acetyltr_2 PF13718.1 KEG13728.1 - 0.14 11.4 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 LRR_4 PF12799.2 KEG13729.1 - 3.8e-17 61.5 7.9 3.1e-07 29.8 0.0 4.0 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG13729.1 - 1.8e-10 40.4 9.5 4e-06 26.4 0.2 3.6 3 0 0 3 3 3 3 Leucine rich repeat LRR_9 PF14580.1 KEG13729.1 - 1.4e-06 27.9 0.9 9.9e-05 21.9 0.1 2.7 1 1 1 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.28 KEG13729.1 - 1.8e-05 24.1 7.5 2.1 8.7 0.0 6.8 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_6 PF13516.1 KEG13729.1 - 0.0001 22.0 3.8 2.7 8.3 0.0 5.7 5 2 1 6 6 6 1 Leucine Rich repeat LRR_7 PF13504.1 KEG13729.1 - 0.00038 20.2 10.0 0.31 11.4 0.1 6.6 7 0 0 7 7 7 1 Leucine rich repeat FNIP PF05725.7 KEG13729.1 - 0.11 12.4 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 FNIP Repeat Neur_chan_memb PF02932.11 KEG13729.1 - 0.12 12.2 7.5 0.15 11.8 0.5 2.3 1 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SPX PF03105.14 KEG13729.1 - 9.7 5.8 23.1 65 3.1 16.0 2.2 1 1 0 1 1 1 0 SPX domain CH PF00307.26 KEG13730.1 - 0.00013 21.9 0.0 0.00056 19.9 0.0 2.1 2 0 0 2 2 2 1 Calponin homology (CH) domain DUF720 PF05302.6 KEG13730.1 - 0.00092 18.9 0.1 0.0028 17.4 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF720) CAMSAP_CH PF11971.3 KEG13730.1 - 0.066 12.8 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 CAMSAP CH domain HALZ PF02183.13 KEG13730.1 - 0.11 12.1 9.2 0.14 11.9 0.2 4.0 3 0 0 3 3 3 0 Homeobox associated leucine zipper CtaG_Cox11 PF04442.9 KEG13731.1 - 2.1e-45 154.2 0.1 3.1e-45 153.6 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 DNA_primase_lrg PF04104.9 KEG13732.1 - 6.6e-79 264.8 0.0 8.9e-79 264.4 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Acyltransferase PF01553.16 KEG13733.1 - 1.9e-14 53.2 0.0 6.9e-14 51.4 0.0 2.0 1 1 0 1 1 1 1 Acyltransferase DUF3270 PF11674.3 KEG13733.1 - 6.1 6.9 8.2 2.6 8.1 2.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) Met_10 PF02475.11 KEG13735.1 - 1.7e-40 138.7 0.0 1e-35 123.1 0.0 2.2 2 0 0 2 2 2 2 Met-10+ like-protein Methyltransf_26 PF13659.1 KEG13735.1 - 3.3e-06 27.1 0.3 1e-05 25.5 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KEG13735.1 - 8.4e-06 25.2 0.2 2.8e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_18 PF12847.2 KEG13735.1 - 2.8e-05 24.6 0.0 6.5e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 KEG13735.1 - 0.0021 17.6 0.0 0.0039 16.7 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.1 KEG13735.1 - 0.0067 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 KEG13735.1 - 0.011 15.1 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 tRNA_U5-meth_tr PF05958.6 KEG13735.1 - 0.036 12.7 0.0 0.065 11.9 0.0 1.3 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase DNA_methylase PF00145.12 KEG13735.1 - 0.043 12.9 0.0 0.13 11.3 0.0 1.7 2 0 0 2 2 2 0 C-5 cytosine-specific DNA methylase DUF1656 PF07869.7 KEG13735.1 - 0.31 10.8 2.6 0.56 10.0 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) DSPc PF00782.15 KEG13736.1 - 1e-05 25.1 0.0 1.6e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KEG13736.1 - 5.6e-05 23.4 0.0 9.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 KEG13736.1 - 0.0046 16.3 0.0 0.0062 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTEN_C2 PF10409.4 KEG13736.1 - 0.014 15.1 0.1 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein PTPlike_phytase PF14566.1 KEG13736.1 - 0.028 14.4 0.1 0.046 13.7 0.1 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Myosin_head PF00063.16 KEG13737.1 - 6.8e-184 612.7 0.3 3e-183 610.6 0.2 1.9 1 1 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.22 KEG13737.1 - 5.2e-05 22.5 1.8 0.0028 17.1 0.6 2.8 2 0 0 2 2 2 1 IQ calmodulin-binding motif AAA_22 PF13401.1 KEG13737.1 - 0.033 14.3 0.0 0.48 10.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KEG13737.1 - 0.076 12.5 0.1 0.19 11.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 KEG13737.1 - 8.2 7.2 6.8 8.9 7.1 0.0 3.8 3 1 0 3 3 3 0 AAA domain 2-Hacid_dh_C PF02826.14 KEG13738.1 - 3.4e-10 39.3 0.0 3.8e-10 39.1 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain LRR_6 PF13516.1 KEG13741.1 - 7.9e-25 84.1 29.0 0.0026 17.6 0.1 11.3 12 0 0 12 12 12 7 Leucine Rich repeat LRR_4 PF12799.2 KEG13741.1 - 3.3e-09 36.1 17.3 0.001 18.6 0.4 6.8 3 2 5 8 8 8 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEG13741.1 - 4.5e-09 35.0 17.3 0.9 9.8 0.0 10.3 10 2 0 10 10 10 2 Leucine Rich Repeat LRR_8 PF13855.1 KEG13741.1 - 6.5e-07 29.0 20.2 9.4e-06 25.2 0.1 6.5 5 3 2 7 7 7 2 Leucine rich repeat LRR_7 PF13504.1 KEG13741.1 - 0.0048 16.8 18.5 2.4 8.7 0.1 9.1 9 0 0 9 9 9 1 Leucine rich repeat DUF1664 PF07889.7 KEG13741.1 - 9.7 6.0 10.4 12 5.6 1.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) IU_nuc_hydro PF01156.14 KEG13742.1 - 1.6e-50 172.0 0.0 1.8e-50 171.9 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF4131 PF13567.1 KEG13743.1 - 3.7 6.9 7.9 3.5 7.0 1.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Mito_carr PF00153.22 KEG13744.1 - 1.3e-58 194.6 3.3 1.1e-19 69.9 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Trypsin_2 PF13365.1 KEG13745.1 - 0.00024 21.0 1.2 0.00042 20.3 0.8 1.4 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S32 PF05579.8 KEG13745.1 - 0.0016 17.4 0.1 0.0024 16.8 0.1 1.3 1 0 0 1 1 1 1 Equine arteritis virus serine endopeptidase S32 Peptidase_S29 PF02907.10 KEG13745.1 - 0.017 14.6 0.1 0.032 13.7 0.1 1.5 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease TPR_19 PF14559.1 KEG13746.1 - 9.9e-15 54.6 0.0 0.00079 19.7 0.0 5.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 KEG13746.1 - 1.5e-11 44.5 0.6 0.00041 20.9 0.1 5.5 5 1 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 KEG13746.1 - 2.3e-10 40.4 17.0 0.0012 18.9 2.0 5.6 3 2 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 KEG13746.1 - 6.8e-10 38.6 1.3 0.1 13.3 0.0 5.9 7 0 0 7 7 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEG13746.1 - 6.8e-09 34.9 23.6 0.021 14.6 0.1 7.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.1 KEG13746.1 - 1e-07 31.4 13.9 9.4e-05 21.9 0.0 5.0 5 1 1 6 6 5 2 TPR repeat TPR_1 PF00515.23 KEG13746.1 - 8.1e-05 22.0 11.1 0.31 10.7 0.1 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 KEG13746.1 - 0.00016 21.8 4.6 13 6.5 0.0 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat Coatomer_E PF04733.9 KEG13746.1 - 0.00053 19.2 4.3 0.23 10.6 0.9 3.4 3 0 0 3 3 3 2 Coatomer epsilon subunit TPR_9 PF13371.1 KEG13746.1 - 0.00089 19.0 1.3 0.13 12.1 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 KEG13746.1 - 0.001 18.9 12.4 0.57 10.1 0.1 6.2 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEG13746.1 - 0.0045 16.6 2.7 0.4 10.6 0.2 4.2 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_4 PF07721.9 KEG13746.1 - 0.0057 16.9 0.0 3.2 8.4 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 KEG13746.1 - 0.021 14.7 4.2 5.4 7.1 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KEG13746.1 - 0.13 12.1 6.4 2 8.3 0.2 4.3 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.7 KEG13746.1 - 1.6 8.5 7.9 11 5.9 0.3 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Actin PF00022.14 KEG13747.1 - 2.1e-16 59.3 0.0 4.6e-14 51.6 0.0 2.9 1 1 1 2 2 2 1 Actin START PF01852.14 KEG13748.1 - 1.2e-27 96.6 0.0 2.1e-27 95.8 0.0 1.4 1 1 0 1 1 1 1 START domain DUF3074 PF11274.3 KEG13748.1 - 0.00048 19.7 0.1 0.0053 16.4 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3074) Pkinase PF00069.20 KEG13749.1 - 2.2e-32 112.2 0.0 7e-32 110.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG13749.1 - 1.8e-21 76.3 0.0 3.1e-21 75.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 KEG13749.1 - 0.008 15.5 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 KEG13749.1 - 0.019 14.0 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HalX PF08663.5 KEG13749.1 - 0.1 12.5 2.8 0.1 12.5 0.3 2.1 2 0 0 2 2 2 0 HalX domain Beta_helix PF13229.1 KEG13750.1 - 2.7e-22 79.2 15.6 5.2e-17 62.0 4.7 2.1 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.8 KEG13750.1 - 1.4e-12 47.3 0.1 1.7e-12 46.9 0.1 1.1 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Pectate_lyase_3 PF12708.2 KEG13750.1 - 0.0052 16.9 1.6 0.015 15.4 0.9 1.8 1 1 0 1 1 1 1 Pectate lyase superfamily protein DUF1565 PF07602.6 KEG13750.1 - 0.0068 15.5 0.6 0.23 10.5 0.3 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1565) Hexapep PF00132.19 KEG13750.1 - 0.023 14.1 2.0 0.35 10.4 0.1 3.1 3 1 0 3 3 3 0 Bacterial transferase hexapeptide (six repeats) zf-met PF12874.2 KEG13752.1 - 0.002 18.2 0.1 0.005 17.0 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-met2 PF12907.2 KEG13752.1 - 0.022 14.7 0.0 0.022 14.7 0.0 1.8 2 0 0 2 2 1 0 Zinc-binding zf-C2H2_4 PF13894.1 KEG13752.1 - 0.028 14.7 0.2 0.028 14.7 0.1 1.9 2 0 0 2 2 1 0 C2H2-type zinc finger Band_3_cyto PF07565.8 KEG13752.1 - 0.033 13.7 2.8 0.04 13.4 2.0 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain FimP PF09766.4 KEG13752.1 - 0.042 12.9 13.3 0.059 12.4 9.2 1.1 1 0 0 1 1 1 0 Fms-interacting protein Zip PF02535.17 KEG13752.1 - 0.15 11.0 0.4 0.21 10.5 0.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter OATP PF03137.15 KEG13752.1 - 0.35 8.8 3.8 0.49 8.3 2.6 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family AIF_C PF14721.1 KEG13752.1 - 0.36 11.0 5.1 0.7 10.1 3.5 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Hid1 PF12722.2 KEG13752.1 - 0.57 7.8 5.3 0.74 7.4 3.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FYDLN_acid PF09538.5 KEG13752.1 - 0.77 10.3 4.9 14 6.3 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Peptidase_S49_N PF08496.5 KEG13752.1 - 5 6.9 7.3 7.7 6.2 5.0 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF2254 PF10011.4 KEG13752.1 - 7.3 4.9 5.4 11 4.3 3.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) PDEase_I PF00233.14 KEG13753.1 - 1.5e-41 142.7 0.0 3e-41 141.7 0.0 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase FYVE PF01363.16 KEG13753.1 - 1.2e-07 31.4 17.6 3.3e-07 30.0 12.2 1.8 1 0 0 1 1 1 1 FYVE zinc finger Reo_sigmaC PF04582.7 KEG13753.1 - 0.17 11.0 2.1 5.9 5.9 0.2 2.4 2 0 0 2 2 2 0 Reovirus sigma C capsid protein PilJ PF13675.1 KEG13753.1 - 0.44 10.8 14.2 0.8 10.0 0.1 4.9 3 2 1 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term Pkinase PF00069.20 KEG13754.1 - 2.4e-61 207.1 0.0 2.4e-61 207.1 0.0 1.6 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG13754.1 - 2.2e-40 138.3 0.2 3.8e-40 137.6 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG13754.1 - 1.1e-11 44.3 0.0 3.1e-09 36.2 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KEG13754.1 - 0.016 14.9 0.0 0.043 13.5 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family PHD_3 PF13922.1 KEG13754.1 - 4.9 7.4 6.0 31 4.8 2.6 2.4 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx Helicase_C_2 PF13307.1 KEG13755.1 - 2.3e-48 164.2 0.0 5.2e-48 163.1 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 KEG13755.1 - 6.7e-43 146.0 0.0 1.2e-42 145.2 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.10 KEG13755.1 - 5.4e-05 23.1 0.0 0.00041 20.2 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KEG13755.1 - 6.7e-05 22.4 0.0 0.00086 18.8 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_19 PF13245.1 KEG13755.1 - 0.0031 17.2 4.2 0.0031 17.2 0.0 3.1 2 0 0 2 2 2 1 Part of AAA domain AAA_11 PF13086.1 KEG13755.1 - 0.0039 16.7 0.0 0.0079 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain SNF2_N PF00176.18 KEG13755.1 - 0.22 10.3 0.0 2 7.1 0.0 2.2 1 1 0 1 1 1 0 SNF2 family N-terminal domain Rotamase_3 PF13616.1 KEG13756.1 - 1.7e-22 79.9 0.0 3e-22 79.0 0.0 1.4 1 1 1 2 2 2 1 PPIC-type PPIASE domain Rotamase PF00639.16 KEG13756.1 - 1.7e-22 79.9 0.3 2.7e-22 79.3 0.0 1.4 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 KEG13756.1 - 1.1e-09 38.9 0.0 1.5e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Cnd3 PF12719.2 KEG13757.1 - 3.4e-26 91.9 0.2 6.4e-25 87.7 0.0 2.6 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 KEG13757.1 - 1.4e-05 25.2 5.9 0.003 17.8 0.0 5.1 5 1 0 6 6 6 1 HEAT repeats HEAT PF02985.17 KEG13757.1 - 0.016 15.2 8.9 4.7 7.5 0.5 5.4 5 0 0 5 5 5 0 HEAT repeat CLASP_N PF12348.3 KEG13757.1 - 0.052 12.9 0.7 1.1 8.6 0.0 2.7 2 0 0 2 2 2 0 CLASP N terminal Laminin_G_3 PF13385.1 KEG13759.1 - 1.8e-27 96.5 15.6 7.9e-22 78.1 0.0 5.9 5 0 0 5 5 5 2 Concanavalin A-like lectin/glucanases superfamily Lectin_C PF00059.16 KEG13759.1 - 5.1e-13 49.5 0.3 2.5e-12 47.3 0.0 2.5 2 0 0 2 2 2 1 Lectin C-type domain CHB_HEX_C PF03174.8 KEG13759.1 - 0.0065 16.2 0.2 0.026 14.3 0.1 2.1 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain Chordopox_A33R PF05966.7 KEG13759.1 - 0.0073 15.1 0.6 0.19 10.4 0.0 2.3 2 0 0 2 2 2 1 Chordopoxvirus A33R protein Tweety PF04906.8 KEG13759.1 - 0.084 11.2 0.0 0.15 10.4 0.0 1.3 1 0 0 1 1 1 0 Tweety IncA PF04156.9 KEG13759.1 - 0.37 10.3 0.1 0.64 9.5 0.1 1.2 1 0 0 1 1 1 0 IncA protein DUF1410 PF07198.6 KEG13759.1 - 1.1 9.6 3.4 1.7 9.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1410) Hist_deacetyl PF00850.14 KEG13764.1 - 2.7e-61 207.5 0.0 4e-61 207.0 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Mito_fiss_reg PF05308.6 KEG13765.1 - 0.028 13.8 0.6 0.057 12.7 0.4 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 KEG13765.1 - 4.6 6.4 7.3 7 5.8 5.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal AAA_5 PF07728.9 KEG13766.1 - 3.8e-85 282.6 0.1 4.6e-30 104.1 0.0 3.6 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KEG13766.1 - 1.3e-08 35.1 0.2 0.0025 17.8 0.0 3.6 3 1 0 3 3 2 2 AAA ATPase domain AAA_2 PF07724.9 KEG13766.1 - 2.4e-08 34.0 0.0 0.012 15.5 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) VWA_2 PF13519.1 KEG13766.1 - 9.7e-07 29.0 0.0 6.8e-06 26.2 0.0 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain AAA_14 PF13173.1 KEG13766.1 - 1.1e-06 28.6 0.0 0.00045 20.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KEG13766.1 - 4.1e-06 26.2 0.0 0.079 12.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.24 KEG13766.1 - 8.9e-06 25.9 0.0 0.035 14.3 0.0 3.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KEG13766.1 - 6.1e-05 22.5 0.2 0.74 9.2 0.0 3.5 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_22 PF13401.1 KEG13766.1 - 6.3e-05 23.1 0.8 0.0021 18.2 0.1 3.4 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 KEG13766.1 - 0.00018 21.1 0.6 0.28 10.8 0.0 3.2 3 0 0 3 3 2 1 NACHT domain Mg_chelatase PF01078.16 KEG13766.1 - 0.00024 20.3 3.8 0.0077 15.4 0.1 3.8 3 1 0 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KEG13766.1 - 0.00056 19.5 0.0 0.6 9.7 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 KEG13766.1 - 0.00074 19.8 0.0 0.0091 16.2 0.0 2.6 2 0 0 2 2 2 1 ABC transporter MCM PF00493.18 KEG13766.1 - 0.0014 17.5 0.1 0.84 8.3 0.0 2.4 2 0 0 2 2 2 2 MCM2/3/5 family AAA_18 PF13238.1 KEG13766.1 - 0.0016 18.7 0.0 0.02 15.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 KEG13766.1 - 0.0017 17.8 0.0 0.02 14.4 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.1 KEG13766.1 - 0.0018 19.1 0.0 0.038 14.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 KEG13766.1 - 0.0023 16.8 0.0 0.72 8.7 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF815) T2SE PF00437.15 KEG13766.1 - 0.0051 15.7 0.0 0.065 12.1 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Rad17 PF03215.10 KEG13766.1 - 0.0056 15.4 0.0 0.0098 14.6 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein DUF258 PF03193.11 KEG13766.1 - 0.0065 15.6 0.0 0.8 8.8 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function, DUF258 VWA PF00092.23 KEG13766.1 - 0.014 15.1 0.0 0.052 13.2 0.0 1.9 2 0 0 2 2 1 0 von Willebrand factor type A domain Arch_ATPase PF01637.13 KEG13766.1 - 0.015 15.0 0.0 0.04 13.5 0.0 1.6 2 0 0 2 2 1 0 Archaeal ATPase RuvB_N PF05496.7 KEG13766.1 - 0.024 13.6 0.2 0.76 8.7 0.1 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus ATP-synt_ab PF00006.20 KEG13766.1 - 0.026 14.0 0.0 0.33 10.4 0.0 2.6 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain Arf PF00025.16 KEG13766.1 - 0.035 13.3 0.1 4.1 6.6 0.0 2.6 2 0 0 2 2 2 0 ADP-ribosylation factor family TrwB_AAD_bind PF10412.4 KEG13766.1 - 0.048 12.2 0.0 0.41 9.2 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain IstB_IS21 PF01695.12 KEG13766.1 - 0.06 12.7 0.1 3.4 7.0 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_23 PF13476.1 KEG13766.1 - 0.066 13.5 0.0 0.21 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 KEG13766.1 - 0.076 12.6 0.1 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SRP54 PF00448.17 KEG13766.1 - 0.095 12.1 0.3 0.64 9.4 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.17 KEG13766.1 - 0.11 12.7 0.0 1 9.5 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Miro PF08477.8 KEG13766.1 - 0.27 11.7 0.0 5.4 7.5 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein G-alpha PF00503.15 KEG13766.1 - 0.35 9.4 2.1 0.32 9.6 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit PduV-EutP PF10662.4 KEG13766.1 - 0.4 10.1 0.1 1.7 8.1 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TIP49 PF06068.8 KEG13766.1 - 0.56 8.8 0.0 1.6 7.3 0.0 1.6 2 0 0 2 2 2 0 TIP49 C-terminus DnaJ PF00226.26 KEG13767.1 - 1.4e-09 37.4 0.1 3.5e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain SR-25 PF10500.4 KEG13767.1 - 0.12 11.8 12.5 0.17 11.3 8.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MMPL PF03176.10 KEG13767.1 - 0.12 11.0 0.7 0.16 10.6 0.5 1.2 1 0 0 1 1 1 0 MMPL family DUF4407 PF14362.1 KEG13767.1 - 0.25 10.2 10.9 0.31 9.9 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SprA-related PF12118.3 KEG13768.1 - 0.0018 17.6 69.2 0.0018 17.6 47.9 3.2 3 0 0 3 3 3 2 SprA-related family FLO_LFY PF01698.11 KEG13768.1 - 6.9 5.4 34.8 1.9 7.2 20.8 2.4 2 0 0 2 2 2 0 Floricaula / Leafy protein DctQ PF04290.7 KEG13772.1 - 0.19 11.4 3.1 0.22 11.2 2.2 1.1 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component Pkinase PF00069.20 KEG13773.1 - 2.3e-45 154.7 0.0 7.7e-43 146.5 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEG13773.1 - 1.8e-15 56.7 0.0 2.8e-09 36.4 0.2 3.3 3 0 0 3 3 3 2 Protein tyrosine kinase FHA PF00498.21 KEG13773.1 - 2.1e-11 43.7 0.2 3.6e-10 39.8 0.1 2.7 3 0 0 3 3 3 1 FHA domain CHCH PF06747.8 KEG13774.1 - 4e-07 29.7 4.9 5.4e-07 29.3 3.4 1.2 1 0 0 1 1 1 1 CHCH domain DUF2076 PF09849.4 KEG13774.1 - 0.0048 16.9 2.5 0.0053 16.8 1.8 1.3 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Pet191_N PF10203.4 KEG13774.1 - 0.014 15.4 1.4 0.018 15.1 1.0 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 UQ_con PF00179.21 KEG13775.1 - 5.5e-45 152.2 0.0 6.3e-45 152.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KEG13775.1 - 9.7e-05 22.1 0.0 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 KEG13775.1 - 0.012 15.3 0.3 0.024 14.3 0.2 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 KEG13775.1 - 0.028 14.3 0.1 0.036 13.9 0.1 1.3 1 0 0 1 1 1 0 RWD domain Cyclin_N PF00134.18 KEG13776.1 - 0.1 12.1 0.0 0.33 10.5 0.0 1.9 2 0 0 2 2 2 0 Cyclin, N-terminal domain MgtE PF01769.11 KEG13777.1 - 0.014 15.6 8.1 0.085 13.1 0.8 2.8 3 0 0 3 3 3 0 Divalent cation transporter TauE PF01925.14 KEG13777.1 - 3.4 7.0 15.0 0.95 8.8 5.6 2.5 1 1 1 2 2 2 0 Sulfite exporter TauE/SafE CesT PF05932.8 KEG13778.1 - 8.6e-11 41.7 0.0 6.1e-10 38.9 0.0 2.3 2 0 0 2 2 2 1 Tir chaperone protein (CesT) family PDZ_2 PF13180.1 KEG13778.1 - 5.4e-10 39.0 0.4 1.8e-08 34.1 0.4 2.5 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.19 KEG13778.1 - 0.025 14.7 0.0 0.11 12.7 0.0 2.0 2 0 0 2 2 2 0 PDZ domain (Also known as DHR or GLGF) PDZ_1 PF12812.2 KEG13778.1 - 0.045 13.6 0.1 0.28 11.1 0.0 2.1 2 0 0 2 2 2 0 PDZ-like domain Tox-ART-HYE1 PF15634.1 KEG13778.1 - 0.079 11.9 2.5 0.15 11.0 1.7 1.4 1 0 0 1 1 1 0 HYE1 signature containing ADP-ribosyltransferase DUF974 PF06159.8 KEG13780.1 - 4.3e-13 49.3 0.0 2.2e-12 47.0 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF974) WASH_WAHD PF11945.3 KEG13781.1 - 9.8e-30 103.8 0.0 1.5e-16 60.5 0.0 2.1 2 0 0 2 2 2 2 WAHD domain of WASH complex PGP_phosphatase PF09419.5 KEG13782.1 - 0.089 12.1 0.0 0.089 12.1 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase ADK PF00406.17 KEG13783.1 - 2.2e-39 134.7 0.0 2.6e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.1 KEG13783.1 - 2.9e-08 34.5 0.1 5.7e-08 33.6 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KEG13783.1 - 7.9e-07 29.0 0.0 4.3e-06 26.6 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 KEG13783.1 - 3.5e-06 27.3 0.0 8.3e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KEG13783.1 - 0.002 17.2 0.1 0.0029 16.7 0.0 1.6 1 1 0 1 1 1 1 Zeta toxin Thymidylate_kin PF02223.12 KEG13783.1 - 0.0061 15.9 0.1 3.1 7.1 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase AAA_19 PF13245.1 KEG13783.1 - 0.026 14.2 0.1 0.072 12.8 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain AAA PF00004.24 KEG13783.1 - 0.066 13.4 0.3 0.12 12.5 0.2 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEG13783.1 - 0.076 13.1 0.0 0.13 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain VCX_VCY PF15231.1 KEG13784.1 - 0.015 15.6 1.3 4.2 7.7 0.0 2.2 2 0 0 2 2 2 0 Variable charge X/Y family RE_XcyI PF09571.5 KEG13784.1 - 0.028 13.2 0.0 0.039 12.8 0.0 1.1 1 0 0 1 1 1 0 XcyI restriction endonuclease DZR PF12773.2 KEG13785.1 - 0.0021 17.8 0.8 0.0069 16.1 0.5 1.9 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 KEG13785.1 - 0.004 16.3 0.1 0.013 14.7 0.1 1.8 1 0 0 1 1 1 1 zinc-ribbon domain Nudix_N_2 PF14803.1 KEG13785.1 - 0.0081 15.8 1.6 0.11 12.1 0.1 2.8 2 0 0 2 2 2 1 Nudix N-terminal zinc_ribbon_2 PF13240.1 KEG13785.1 - 0.099 12.1 1.8 0.17 11.4 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain SDA1 PF05285.7 KEG13787.1 - 0.00044 19.6 21.0 0.00051 19.4 14.5 1.2 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.7 KEG13787.1 - 0.00077 17.5 22.6 0.00095 17.2 15.7 1.2 1 0 0 1 1 1 1 Nop14-like family Mpp10 PF04006.7 KEG13787.1 - 0.0017 16.8 17.9 0.002 16.5 12.4 1.1 1 0 0 1 1 1 1 Mpp10 protein BUD22 PF09073.5 KEG13787.1 - 0.0056 15.8 16.7 0.0076 15.3 11.5 1.2 1 0 0 1 1 1 1 BUD22 CobT PF06213.7 KEG13787.1 - 0.0065 15.6 21.6 0.01 14.9 15.0 1.4 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT TFIIA PF03153.8 KEG13787.1 - 0.012 15.5 18.1 0.012 15.5 12.6 1.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Daxx PF03344.10 KEG13787.1 - 0.013 14.0 22.7 0.016 13.6 15.7 1.1 1 0 0 1 1 1 0 Daxx Family Merozoite_SPAM PF07133.6 KEG13787.1 - 0.016 15.1 21.9 0.021 14.7 14.5 1.6 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) DUF2201_N PF13203.1 KEG13787.1 - 0.098 11.8 5.4 0.15 11.2 3.8 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain SAPS PF04499.10 KEG13787.1 - 0.13 10.8 5.6 0.15 10.6 3.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2151 PF10221.4 KEG13787.1 - 0.16 10.1 7.9 0.18 9.9 5.5 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Ycf1 PF05758.7 KEG13787.1 - 0.16 9.6 2.1 0.18 9.5 1.5 1.1 1 0 0 1 1 1 0 Ycf1 Vfa1 PF08432.5 KEG13787.1 - 0.25 11.3 7.5 0.54 10.2 5.2 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 VID27 PF08553.5 KEG13787.1 - 0.62 8.2 14.8 0.74 7.9 10.3 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein SpoIIIAH PF12685.2 KEG13787.1 - 1.4 8.4 10.4 2.6 7.4 7.2 1.5 1 0 0 1 1 1 0 SpoIIIAH-like protein Trypan_PARP PF05887.6 KEG13787.1 - 1.5 8.6 21.7 2.3 8.0 15.0 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RRN3 PF05327.6 KEG13787.1 - 1.6 6.7 13.1 0.99 7.4 8.0 1.5 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 DUF1510 PF07423.6 KEG13787.1 - 2.6 7.3 20.1 3.8 6.8 13.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) eIF-3c_N PF05470.7 KEG13787.1 - 5.1 5.0 11.6 7.2 4.5 8.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Astro_capsid PF03115.9 KEG13787.1 - 5.2 5.1 8.9 6.9 4.7 6.2 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Prog_receptor PF02161.10 KEG13787.1 - 6.1 5.5 9.3 7.8 5.1 6.5 1.1 1 0 0 1 1 1 0 Progesterone receptor TRAP_alpha PF03896.11 KEG13787.1 - 6.1 5.7 17.0 9 5.1 11.8 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Voltage_CLC PF00654.15 KEG13788.1 - 1.2e-89 300.8 29.0 1.2e-89 300.8 20.1 1.9 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 KEG13788.1 - 1.2e-11 44.1 3.7 9.8e-05 22.0 0.0 3.6 3 0 0 3 3 3 2 CBS domain TAT_signal PF10518.4 KEG13788.1 - 0.0096 15.8 0.1 0.0096 15.8 0.1 4.2 4 0 0 4 4 4 1 TAT (twin-arginine translocation) pathway signal sequence Afi1 PF07792.7 KEG13788.1 - 0.15 12.0 5.5 0.035 14.1 1.3 1.7 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Secretin_N_2 PF07655.8 KEG13788.1 - 6.4 7.2 15.3 15 6.0 10.6 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain Taeniidae_ag PF05596.6 KEG13789.1 - 0.0065 16.2 0.1 0.01 15.6 0.1 1.3 1 0 0 1 1 1 1 Taeniidae antigen PT-VENN PF04829.8 KEG13790.1 - 0.054 13.0 0.7 0.2 11.2 0.5 2.0 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif TFIIA PF03153.8 KEG13790.1 - 2.7 7.7 7.9 3.5 7.4 5.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-CCCH PF00642.19 KEG13791.1 - 1e-13 50.5 39.7 0.00068 19.2 0.2 5.8 6 0 0 6 6 6 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCHC PF00098.18 KEG13791.1 - 5.2e-07 29.2 14.3 0.0056 16.5 0.8 3.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 KEG13791.1 - 0.067 12.9 0.0 0.067 12.9 0.0 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-C3H1 PF10650.4 KEG13791.1 - 0.067 12.6 0.1 0.067 12.6 0.1 3.7 4 0 0 4 4 4 0 Putative zinc-finger domain zf-CCHC_4 PF14392.1 KEG13791.1 - 0.47 10.1 10.6 0.3 10.7 3.1 2.8 2 0 0 2 2 2 0 Zinc knuckle zf-CCCH_2 PF14608.1 KEG13791.1 - 0.56 10.2 0.1 0.56 10.3 0.5 6.0 7 0 0 7 7 7 0 Zinc finger C-x8-C-x5-C-x3-H type zf-CCHC_2 PF13696.1 KEG13791.1 - 1.3 8.5 17.9 0.72 9.4 2.5 3.3 3 0 0 3 3 3 0 Zinc knuckle zf-UBR PF02207.15 KEG13793.1 - 3.9e-15 55.3 12.1 3.9e-15 55.3 8.4 2.5 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) Atrophin-1 PF03154.10 KEG13793.1 - 0.4 8.7 1.4 0.59 8.1 1.0 1.1 1 0 0 1 1 1 0 Atrophin-1 family Ribonuc_red_sm PF00268.16 KEG13794.1 - 2.1e-116 387.8 0.7 2.5e-116 387.5 0.5 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain ACBP PF00887.14 KEG13795.1 - 1.7e-25 88.4 0.3 3.2e-25 87.5 0.2 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein DUF4486 PF14858.1 KEG13796.1 - 2.3e-09 36.0 0.1 4.1e-09 35.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4486) Cohesin_load PF10345.4 KEG13796.1 - 3.3e-07 28.9 0.3 7.3e-06 24.4 0.0 2.3 2 0 0 2 2 2 1 Cohesin loading factor TPR_12 PF13424.1 KEG13796.1 - 0.003 17.4 31.7 0.073 13.0 0.6 8.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.12 KEG13796.1 - 0.45 10.5 27.0 1.7 8.7 0.4 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 KEG13796.1 - 3.3 7.4 11.2 2 8.1 0.2 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 KEG13796.1 - 9.7 6.2 9.7 5.5 7.0 0.2 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TK PF00265.13 KEG13797.1 - 7.2e-06 25.6 0.0 9.8e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Thymidine kinase Peptidase_S9 PF00326.16 KEG13798.1 - 6.6e-67 224.8 0.0 7.8e-67 224.5 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.10 KEG13798.1 - 2.5e-06 26.3 0.1 3.3e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9_N PF02897.10 KEG13799.1 - 6e-41 140.3 0.0 6.6e-41 140.2 0.0 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF4464 PF14713.1 KEG13800.1 - 3.7e-85 285.0 0.3 4.2e-85 284.8 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) Pyr_redox_2 PF07992.9 KEG13802.1 - 2.8e-28 99.1 0.0 1.1e-27 97.2 0.0 1.8 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEG13802.1 - 3.4e-21 75.4 1.8 2.2e-18 66.4 0.0 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KEG13802.1 - 3.8e-18 65.5 0.6 9.7e-18 64.2 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_3 PF13738.1 KEG13802.1 - 2.4e-12 47.3 2.2 1.3e-09 38.4 0.6 3.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KEG13802.1 - 1.5e-07 30.8 0.6 2.9e-07 29.9 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.19 KEG13802.1 - 3.7e-07 29.3 5.5 0.0013 17.6 0.6 3.9 3 1 1 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 KEG13802.1 - 3.1e-05 23.0 0.4 0.00022 20.2 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 KEG13802.1 - 3.2e-05 22.9 1.6 0.015 14.2 0.6 2.6 2 1 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.1 KEG13802.1 - 4.1e-05 23.5 2.4 0.021 14.8 0.5 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KEG13802.1 - 9.2e-05 21.6 0.3 0.0059 15.7 0.1 2.3 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 KEG13802.1 - 0.00014 20.5 8.0 0.0017 16.9 0.8 3.5 3 1 1 4 4 4 1 HI0933-like protein 3HCDH_N PF02737.13 KEG13802.1 - 0.00051 19.7 0.4 0.001 18.7 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 KEG13802.1 - 0.00067 18.8 1.4 0.09 11.8 0.1 3.3 3 1 0 3 3 3 1 FAD binding domain 2-Hacid_dh_C PF02826.14 KEG13802.1 - 0.00089 18.4 0.0 0.0033 16.6 0.0 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 KEG13802.1 - 0.0018 18.5 0.4 2.8 8.2 0.0 2.9 3 0 0 3 3 3 2 Putative NAD(P)-binding FAD_binding_2 PF00890.19 KEG13802.1 - 0.0032 16.3 6.4 0.0034 16.3 1.1 2.9 3 0 0 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.7 KEG13802.1 - 0.0074 15.2 1.8 0.14 11.0 0.6 2.5 2 1 0 2 2 2 1 Lycopene cyclase protein ThiF PF00899.16 KEG13802.1 - 0.02 14.7 0.8 0.048 13.4 0.0 2.1 2 0 0 2 2 1 0 ThiF family AlaDh_PNT_C PF01262.16 KEG13802.1 - 0.021 14.3 0.3 0.49 9.9 0.0 2.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 KEG13802.1 - 0.11 12.6 1.8 0.97 9.5 0.1 2.8 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.9 KEG13802.1 - 1.9 6.9 4.7 5.3 5.5 0.4 3.3 3 1 1 4 4 4 0 Tryptophan halogenase NAD_binding_9 PF13454.1 KEG13802.1 - 9.1 6.0 7.0 3 7.6 0.3 3.3 3 1 0 3 3 3 0 FAD-NAD(P)-binding Bac_surface_Ag PF01103.18 KEG13803.1 - 5.5e-19 68.7 1.4 9.9e-19 67.9 1.0 1.5 1 1 0 1 1 1 1 Surface antigen Folliculin PF11704.3 KEG13804.1 - 3.2e-12 46.3 0.0 5.8e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport TAT_ubiq PF07706.7 KEG13805.1 - 1.9e-06 27.6 4.8 5.2 7.0 0.1 6.9 1 1 5 6 6 6 1 Aminotransferase ubiquitination site DUF3728 PF12528.3 KEG13805.1 - 0.12 12.7 0.1 0.5 10.7 0.0 1.9 2 0 0 2 2 2 0 Prepilin peptidase dependent protein C (DUF3728) TPR_11 PF13414.1 KEG13806.1 - 7.2e-16 57.6 7.0 1.8e-13 49.9 0.3 2.6 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KEG13806.1 - 4.7e-10 38.6 0.5 0.00081 18.8 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEG13806.1 - 5.5e-10 38.3 5.1 0.00031 20.4 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 KEG13806.1 - 7e-08 32.0 0.7 0.0022 18.0 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEG13806.1 - 1.6e-05 25.4 1.9 1.6e-05 25.4 1.3 3.2 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEG13806.1 - 0.00019 21.7 8.0 0.0083 16.6 0.9 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 KEG13806.1 - 0.00031 19.9 0.5 0.056 12.4 0.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KEG13806.1 - 0.0012 18.4 0.4 0.99 9.3 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 KEG13806.1 - 0.0013 18.5 2.0 0.0039 16.9 1.3 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEG13806.1 - 0.0092 16.3 6.1 0.14 12.5 0.5 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat BTAD PF03704.12 KEG13806.1 - 0.013 15.8 6.3 0.018 15.3 2.6 2.4 2 1 1 3 3 3 0 Bacterial transcriptional activator domain TPR_7 PF13176.1 KEG13806.1 - 0.74 9.7 0.0 0.74 9.7 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 KEG13806.1 - 2.6 8.0 7.8 1.6 8.7 0.5 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat Ribosomal_S8 PF00410.14 KEG13807.1 - 3.4e-24 85.1 0.0 4.6e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 DUF1995 PF09353.5 KEG13807.1 - 0.12 11.9 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1995) PTCB-BRCT PF12738.2 KEG13808.1 - 9.2e-19 67.0 0.1 3.5e-12 45.9 0.0 4.7 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.21 KEG13808.1 - 4.5e-14 52.3 0.0 4.5e-05 23.5 0.0 5.3 6 0 0 6 6 6 3 BRCA1 C Terminus (BRCT) domain Diphthamide_syn PF01866.12 KEG13809.1 - 3.9e-112 374.4 0.0 4.6e-112 374.2 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Flagellar_rod PF05149.7 KEG13810.1 - 6.6e-109 363.5 33.2 6.6e-109 363.5 23.0 3.1 2 1 1 3 3 3 2 Paraflagellar rod protein MutS_V PF00488.16 KEG13811.1 - 2.8e-29 102.2 0.2 4.7e-29 101.4 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KEG13811.1 - 3.7e-23 82.3 0.0 6.4e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 MutS domain III AAA_22 PF13401.1 KEG13811.1 - 0.00084 19.4 0.1 0.0032 17.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain MutS_IV PF05190.13 KEG13811.1 - 0.00094 19.3 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV AAA_30 PF13604.1 KEG13811.1 - 0.0042 16.6 0.1 0.011 15.3 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KEG13811.1 - 0.0055 16.2 0.0 0.022 14.2 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.14 KEG13811.1 - 0.011 15.0 0.0 0.023 13.9 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Viral_helicase1 PF01443.13 KEG13811.1 - 0.011 15.2 0.1 2.7 7.4 0.1 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 KEG13811.1 - 0.016 15.2 0.2 0.057 13.4 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 KEG13811.1 - 0.09 12.5 1.7 0.18 11.5 0.1 2.4 3 0 0 3 3 3 0 Part of AAA domain AAA_10 PF12846.2 KEG13811.1 - 0.13 11.7 0.1 1.4 8.3 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain AAA_21 PF13304.1 KEG13811.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KEG13811.1 - 0.34 11.1 0.0 0.57 10.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain MORN PF02493.15 KEG13812.1 - 1e-67 220.0 113.9 5.3e-05 22.7 0.2 23.6 24 1 0 24 24 24 20 MORN repeat 4HBT PF03061.17 KEG13813.1 - 2.3e-15 56.4 2.9 2.2e-08 34.0 1.2 2.4 2 0 0 2 2 2 2 Thioesterase superfamily 4HBT_2 PF13279.1 KEG13813.1 - 1e-05 25.9 0.2 0.0007 20.0 0.1 2.3 2 0 0 2 2 2 1 Thioesterase-like superfamily MaoC_dehydratas PF01575.14 KEG13813.1 - 0.00019 20.7 0.4 0.65 9.3 0.0 2.4 2 0 0 2 2 2 2 MaoC like domain 4HBT PF03061.17 KEG13814.1 - 3.2e-14 52.8 3.8 9.7e-07 28.8 0.3 2.5 2 0 0 2 2 2 2 Thioesterase superfamily 4HBT_2 PF13279.1 KEG13814.1 - 0.11 13.0 0.0 8.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Thioesterase-like superfamily DASH_Dad2 PF08654.5 KEG13815.1 - 0.012 15.5 1.2 0.073 13.0 0.3 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad2 DUF1192 PF06698.6 KEG13815.1 - 0.14 12.0 3.3 2.1 8.2 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TBPIP PF07106.8 KEG13815.1 - 0.15 11.6 2.1 0.72 9.3 1.1 1.9 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DMPK_coil PF08826.5 KEG13815.1 - 0.22 11.4 8.2 0.062 13.2 2.2 2.4 3 0 0 3 3 3 0 DMPK coiled coil domain like IncA PF04156.9 KEG13815.1 - 0.49 9.9 4.7 0.54 9.8 2.6 1.5 2 0 0 2 2 2 0 IncA protein Thioredoxin PF00085.15 KEG13816.1 - 1e-12 47.6 0.0 2.2e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 KEG13816.1 - 1.7e-07 31.4 0.0 4.2e-07 30.1 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KEG13816.1 - 6.8e-06 26.1 0.0 0.00019 21.4 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin-like Redoxin PF08534.5 KEG13816.1 - 0.026 14.0 0.0 0.086 12.3 0.0 1.8 2 0 0 2 2 2 0 Redoxin Thioredoxin_7 PF13899.1 KEG13816.1 - 0.032 14.2 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like AhpC-TSA PF00578.16 KEG13816.1 - 0.035 13.7 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family Glutaredoxin PF00462.19 KEG13816.1 - 0.081 12.9 0.0 0.37 10.8 0.0 1.9 2 0 0 2 2 2 0 Glutaredoxin Peptidase_S8 PF00082.17 KEG13817.1 - 1.4e-30 106.3 0.0 2.4e-30 105.6 0.0 1.3 1 0 0 1 1 1 1 Subtilase family CUB PF00431.15 KEG13817.1 - 1.1e-09 38.2 0.0 3.6e-09 36.6 0.0 1.9 1 0 0 1 1 1 1 CUB domain EGF_2 PF07974.8 KEG13817.1 - 5.4 7.2 89.0 0.32 11.1 9.6 6.2 4 1 1 5 5 5 0 EGF-like domain ABC_tran PF00005.22 KEG13818.1 - 6.3e-28 97.7 0.0 9.5e-28 97.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KEG13818.1 - 1.3e-10 41.7 0.6 1e-07 32.1 0.1 2.3 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KEG13818.1 - 0.00095 18.4 0.0 0.041 13.1 0.0 2.3 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_19 PF13245.1 KEG13818.1 - 0.024 14.3 0.5 0.11 12.2 0.2 2.1 2 0 0 2 2 2 0 Part of AAA domain AAA_30 PF13604.1 KEG13818.1 - 0.027 14.0 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KEG13818.1 - 0.036 13.2 0.0 0.059 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 KEG13818.1 - 0.036 13.5 0.1 0.067 12.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.7 KEG13818.1 - 0.053 13.1 1.2 0.22 11.1 0.1 2.1 2 0 0 2 2 2 0 NACHT domain SbcCD_C PF13558.1 KEG13818.1 - 0.063 13.2 0.9 1 9.3 0.2 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 KEG13818.1 - 0.15 12.0 0.4 0.25 11.2 0.3 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 KEG13818.1 - 0.15 11.4 0.7 0.7 9.2 0.4 1.9 1 1 1 2 2 2 0 AAA-like domain RINGv PF12906.2 KEG13819.1 - 6.7e-11 42.0 9.4 1.7e-10 40.7 6.5 1.7 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 KEG13819.1 - 4.3e-06 26.4 6.3 1.4e-05 24.8 4.4 2.0 1 0 0 1 1 1 1 Ring finger domain zf-RING-like PF08746.6 KEG13819.1 - 0.046 13.7 3.0 0.13 12.2 2.1 1.8 1 0 0 1 1 1 0 RING-like domain zf-C3HC4 PF00097.20 KEG13819.1 - 4 7.1 6.2 12 5.6 4.3 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ABC2_membrane_3 PF12698.2 KEG13820.1 - 4.5e-35 121.3 25.8 3.2e-34 118.4 17.9 1.9 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.22 KEG13820.1 - 6.1e-24 84.8 0.0 1.2e-23 83.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KEG13820.1 - 4e-09 36.8 0.0 1.2e-06 28.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain DUF70 PF01901.11 KEG13820.1 - 0.0022 17.1 5.5 0.0045 16.0 3.8 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF70 AAA_15 PF13175.1 KEG13820.1 - 0.02 13.9 0.0 0.3 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain SRP54 PF00448.17 KEG13820.1 - 0.066 12.6 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.1 KEG13820.1 - 0.51 10.6 0.3 0.87 9.8 0.2 1.2 1 0 0 1 1 1 0 AAA domain TatD_DNase PF01026.16 KEG13821.1 - 4.6e-42 143.9 0.0 5.7e-42 143.6 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase GCOM2 PF15328.1 KEG13822.1 - 0.0036 17.0 1.3 0.0052 16.5 0.9 1.5 1 1 0 1 1 1 1 Putative GRINL1B complex locus protein 2 4HBT_3 PF13622.1 KEG13823.1 - 2.3e-27 96.3 2.2 1.2e-26 94.0 1.5 1.8 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 KEG13823.1 - 1.4e-21 76.4 0.0 2.6e-17 62.7 0.0 2.9 2 1 1 3 3 3 2 Acyl-CoA thioesterase Arm PF00514.18 KEG13825.1 - 7.2e-08 31.9 3.6 0.024 14.4 0.0 4.9 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KEG13825.1 - 3.4e-05 24.0 17.8 0.098 12.9 2.4 4.4 1 1 3 4 4 4 3 HEAT repeats Proteasom_PSMB PF10508.4 KEG13825.1 - 0.00046 18.5 0.5 0.0012 17.1 0.2 1.6 1 1 1 2 2 2 1 Proteasome non-ATPase 26S subunit HEAT PF02985.17 KEG13825.1 - 0.0016 18.3 15.7 0.96 9.7 0.2 5.9 7 0 0 7 7 7 3 HEAT repeat NblA PF04485.7 KEG13825.1 - 0.11 12.3 0.5 0.91 9.4 0.0 2.4 2 0 0 2 2 2 0 Phycobilisome degradation protein nblA Zea_mays_MuDR PF05928.6 KEG13825.1 - 0.26 10.6 2.8 0.35 10.2 1.0 1.9 1 1 1 2 2 2 0 Zea mays MURB-like protein (MuDR) PapD-like PF14874.1 KEG13827.1 - 6.2e-34 116.0 0.2 1.2e-33 115.0 0.1 1.5 1 0 0 1 1 1 1 Flagellar-associated PapD-like CDC45 PF02724.9 KEG13827.1 - 0.043 11.8 1.3 1.9 6.4 1.4 2.6 2 0 0 2 2 2 0 CDC45-like protein UPF0175 PF03683.8 KEG13827.1 - 0.064 12.7 3.2 0.16 11.4 2.2 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) XAP5 PF04921.9 KEG13827.1 - 4.8 6.6 6.2 10 5.5 4.3 1.5 1 0 0 1 1 1 0 XAP5, circadian clock regulator Nodulin-like PF06813.8 KEG13828.1 - 3.2e-14 52.7 15.0 3.2e-14 52.7 10.4 2.6 2 1 0 2 2 2 2 Nodulin-like MFS_1 PF07690.11 KEG13828.1 - 5.2e-11 41.8 40.0 3.3e-06 26.0 6.6 3.2 2 2 1 3 3 3 3 Major Facilitator Superfamily Ras PF00071.17 KEG13829.1 - 5.7e-50 168.8 0.0 6.8e-50 168.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEG13829.1 - 4e-18 66.0 0.0 5.4e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEG13829.1 - 6e-06 25.6 0.0 7.9e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KEG13829.1 - 7e-06 25.5 0.1 1.1e-05 24.9 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KEG13829.1 - 0.00027 20.8 0.0 0.00041 20.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF972 PF06156.8 KEG13833.1 - 0.04 14.2 1.7 0.062 13.6 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) BLOC1_2 PF10046.4 KEG13833.1 - 0.097 12.8 1.2 0.15 12.2 0.9 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ribosomal_L4 PF00573.17 KEG13834.1 - 4.8e-11 42.3 0.0 1.8e-10 40.4 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein L4/L1 family TruD PF01142.13 KEG13835.1 - 2.8e-09 36.1 0.0 5.4e-08 31.9 0.0 2.8 3 1 1 4 4 4 1 tRNA pseudouridine synthase D (TruD) SH3_9 PF14604.1 KEG13837.1 - 2.4e-10 39.8 0.0 5.5e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KEG13837.1 - 2.9e-09 36.2 0.0 7.7e-09 34.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KEG13837.1 - 6.1e-08 31.9 0.0 1.1e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain DUF2746 PF10874.3 KEG13837.1 - 1.8 8.8 11.3 0.12 12.6 0.7 3.6 2 2 0 2 2 2 0 Protein of unknown function (DUF2746) FHIPEP PF00771.15 KEG13837.1 - 2.2 6.4 7.3 3.1 6.0 5.1 1.1 1 0 0 1 1 1 0 FHIPEP family PI-PLC-X PF00388.14 KEG13838.1 - 1.4e-61 206.1 0.0 2.3e-61 205.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KEG13838.1 - 6e-37 126.2 0.0 1.2e-36 125.2 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 KEG13838.1 - 3.2e-10 39.7 0.0 7.1e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.1 KEG13838.1 - 0.0005 20.1 1.2 0.00086 19.3 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KEG13838.1 - 0.0011 18.0 0.1 0.02 14.1 0.0 2.8 2 0 0 2 2 2 1 EF hand EF-hand_like PF09279.6 KEG13838.1 - 0.0032 17.4 0.0 0.0093 15.9 0.0 1.8 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_6 PF13405.1 KEG13838.1 - 0.006 16.3 0.3 0.74 9.8 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain DUF2029 PF09594.5 KEG13839.1 - 0.063 12.7 0.3 0.082 12.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) DUF2910 PF11139.3 KEG13839.1 - 0.065 12.3 0.0 0.066 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2910) DctQ PF04290.7 KEG13839.1 - 0.081 12.6 0.1 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component WD40 PF00400.27 KEG13841.1 - 8e-12 44.5 11.4 0.0013 18.5 0.2 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat Methyltransf_26 PF13659.1 KEG13843.1 - 0.043 13.8 1.1 4.4 7.3 0.1 3.5 3 0 0 3 3 3 0 Methyltransferase domain PIP5K PF01504.13 KEG13843.1 - 0.36 9.8 0.0 0.62 9.1 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase LSM PF01423.17 KEG13846.1 - 0.00019 20.9 0.0 0.00036 20.0 0.0 1.4 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KEG13846.1 - 0.033 14.1 0.0 0.087 12.7 0.0 1.8 2 0 0 2 2 2 0 Ataxin 2 SM domain zf-C3HC4_2 PF13923.1 KEG13847.1 - 6.7e-10 38.8 13.2 6.7e-10 38.8 9.1 4.5 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEG13847.1 - 4.8e-09 35.7 10.9 4.8e-09 35.7 7.6 4.4 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEG13847.1 - 5.1e-07 29.4 13.5 5.1e-07 29.4 9.4 3.7 4 1 0 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.20 KEG13847.1 - 1.7e-06 27.5 11.0 1.7e-06 27.5 7.6 3.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEG13847.1 - 1e-05 25.1 13.5 1e-05 25.1 9.4 3.7 5 0 0 5 5 5 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KEG13847.1 - 3.3e-05 23.6 12.7 3.3e-05 23.6 8.8 3.2 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KEG13847.1 - 3.7e-05 23.3 8.9 0.00011 21.8 6.2 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 KEG13847.1 - 0.00047 19.8 7.6 0.0019 17.9 5.3 2.0 1 0 0 1 1 1 1 zf-RING of BARD1-type protein U-box PF04564.10 KEG13847.1 - 0.011 15.6 0.0 0.14 12.1 0.0 2.3 2 0 0 2 2 2 0 U-box domain PolC_DP2 PF03833.8 KEG13847.1 - 0.31 8.6 2.4 0.55 7.8 1.7 1.3 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Histone PF00125.19 KEG13848.1 - 2.3e-14 53.2 0.1 3.4e-14 52.7 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 FoP_duplication PF13865.1 KEG13848.1 - 8.4 6.9 10.0 19 5.7 6.9 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 2Fe-2S_thioredx PF01257.14 KEG13849.1 - 9.2e-48 161.5 0.0 1.2e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin RCC1 PF00415.13 KEG13851.1 - 4.3e-69 228.5 24.5 2.2e-15 56.5 0.3 7.6 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KEG13851.1 - 2e-39 132.3 38.5 4.6e-11 42.0 2.6 7.6 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat BTB_2 PF02214.17 KEG13851.1 - 9e-09 35.4 0.0 1.4e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF4213 PF13938.1 KEG13851.1 - 0.028 14.5 1.3 70 3.6 0.1 4.4 4 1 0 4 4 4 0 Domain of unknown function (DUF4213) Pkinase PF00069.20 KEG13852.1 - 7.7e-65 218.6 0.0 7.7e-65 218.6 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain POLO_box PF00659.13 KEG13852.1 - 4.2e-44 148.3 0.2 2.9e-25 88.0 0.1 2.9 2 0 0 2 2 2 2 POLO box duplicated region Pkinase_Tyr PF07714.12 KEG13852.1 - 8.7e-35 120.0 0.0 1.3e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG13852.1 - 5.7e-08 32.0 0.0 1.4e-07 30.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KEG13852.1 - 0.03 14.0 1.9 0.031 14.0 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family WD40 PF00400.27 KEG13853.1 - 1.8e-32 110.0 25.1 1e-08 34.6 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 KEG13853.1 - 1.5e-05 23.3 1.7 0.00015 20.0 0.2 2.8 1 1 2 3 3 3 1 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KEG13853.1 - 0.0098 15.3 0.1 0.88 8.9 0.0 3.0 2 1 0 2 2 2 1 PQQ-like domain DUF3312 PF11768.3 KEG13853.1 - 0.024 12.9 0.2 0.13 10.4 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3312) eIF2A PF08662.6 KEG13853.1 - 0.08 12.6 0.0 0.56 9.8 0.0 2.1 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A Kinesin PF00225.18 KEG13854.1 - 2.9e-80 269.5 0.0 4.4e-80 268.9 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain DUF3508 PF12018.3 KEG13855.1 - 6.4e-08 31.9 0.0 1.1e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3508) Pyr_redox_2 PF07992.9 KEG13856.1 - 6.3e-18 65.3 0.0 7.3e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KEG13856.1 - 1.8e-09 37.2 0.6 2e-09 37.0 0.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEG13856.1 - 5e-09 36.5 0.1 5.8e-09 36.3 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEG13856.1 - 2.1e-06 26.9 1.2 3.6e-06 26.1 0.7 1.4 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEG13856.1 - 2.5e-06 26.6 0.2 2.9e-06 26.4 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KEG13856.1 - 2.5e-06 26.2 0.1 1.9e-05 23.3 0.1 2.0 2 1 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 KEG13856.1 - 1.1e-05 24.4 0.1 2.1e-05 23.6 0.1 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 KEG13856.1 - 1.3e-05 25.1 0.6 0.00013 21.8 0.3 2.2 1 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KEG13856.1 - 0.002 17.1 1.3 0.0034 16.3 0.9 1.6 1 1 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 KEG13856.1 - 0.0038 16.3 0.1 0.0059 15.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 KEG13856.1 - 0.0066 16.2 0.4 0.026 14.2 0.0 2.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KEG13856.1 - 0.012 14.2 0.0 0.017 13.7 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.22 KEG13856.1 - 0.024 15.0 0.4 0.23 11.8 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KEG13856.1 - 0.041 12.9 1.3 0.21 10.6 0.2 2.2 2 1 1 3 3 3 0 FAD binding domain K_oxygenase PF13434.1 KEG13856.1 - 0.12 11.2 0.1 2.9 6.7 0.0 2.0 1 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KEG13857.1 - 6.3e-25 88.2 0.0 1.2e-24 87.3 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KEG13857.1 - 9.8e-17 60.9 0.0 2.9e-16 59.4 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 KEG13857.1 - 2.8e-13 50.0 1.7 2.1e-11 44.0 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KEG13857.1 - 2.4e-08 33.4 0.2 2.4e-08 33.4 0.1 2.2 3 0 0 3 3 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEG13857.1 - 2.4e-08 34.2 0.7 5.4e-07 29.8 0.5 2.6 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEG13857.1 - 3.7e-07 28.9 1.2 0.00033 19.2 0.1 3.1 3 0 0 3 3 3 2 HI0933-like protein NAD_binding_8 PF13450.1 KEG13857.1 - 1.6e-06 28.0 2.2 0.0045 16.9 0.1 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEG13857.1 - 4.9e-06 25.6 1.3 0.0055 15.6 0.3 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 KEG13857.1 - 0.00013 21.0 0.1 0.0018 17.2 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 KEG13857.1 - 0.00023 20.1 3.9 0.034 12.9 0.7 2.8 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KEG13857.1 - 0.00055 18.9 4.0 0.002 17.0 0.3 2.9 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.12 KEG13857.1 - 0.0009 18.4 0.2 0.005 15.9 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 KEG13857.1 - 0.0012 17.8 0.1 0.041 12.7 0.1 2.4 2 0 0 2 2 2 1 Lycopene cyclase protein 3HCDH_N PF02737.13 KEG13857.1 - 0.0039 16.8 0.9 0.018 14.6 0.1 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 KEG13857.1 - 0.0085 15.1 1.0 0.64 9.0 0.0 3.2 3 0 0 3 3 3 1 FAD binding domain ThiF PF00899.16 KEG13857.1 - 0.09 12.6 0.5 0.3 10.8 0.0 2.0 2 0 0 2 2 2 0 ThiF family SR-25 PF10500.4 KEG13857.1 - 3.3 7.1 10.0 5.4 6.4 6.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1191 PF06697.7 KEG13860.1 - 0.0024 16.7 0.1 0.0028 16.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) SieB PF14163.1 KEG13860.1 - 0.003 17.1 0.1 0.004 16.7 0.0 1.1 1 0 0 1 1 1 1 Superinfection exclusion protein B HAMP PF00672.20 KEG13860.1 - 0.0034 17.5 0.0 0.0047 17.0 0.0 1.3 1 0 0 1 1 1 1 HAMP domain DUF2244 PF10003.4 KEG13860.1 - 0.0059 15.9 0.1 0.0069 15.7 0.1 1.1 1 0 0 1 1 1 1 Integral membrane protein (DUF2244) PepSY_TM_2 PF13703.1 KEG13860.1 - 0.01 15.9 0.2 0.013 15.6 0.2 1.2 1 0 0 1 1 1 0 PepSY-associated TM helix RskA PF10099.4 KEG13860.1 - 0.011 15.4 0.0 0.013 15.2 0.0 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA SIT PF15330.1 KEG13860.1 - 0.011 15.8 0.1 0.015 15.4 0.0 1.2 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Herpes_gE PF02480.11 KEG13860.1 - 0.012 13.8 0.0 0.013 13.8 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TMEM52 PF14979.1 KEG13860.1 - 0.013 15.3 0.6 0.021 14.7 0.4 1.3 1 0 0 1 1 1 0 Transmembrane 52 CcmD PF04995.9 KEG13860.1 - 0.016 14.9 2.3 0.029 14.0 1.6 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) UPF0104 PF03706.8 KEG13860.1 - 0.043 13.0 0.3 0.053 12.7 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) EphA2_TM PF14575.1 KEG13860.1 - 0.043 14.2 0.0 0.055 13.8 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain stn_TNFRSF12A PF12191.3 KEG13860.1 - 0.052 13.5 0.3 0.085 12.8 0.2 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF948 PF06103.6 KEG13860.1 - 0.076 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Protocadherin PF08374.6 KEG13860.1 - 0.15 11.7 0.4 0.15 11.6 0.3 1.3 1 1 0 1 1 1 0 Protocadherin WBP-1 PF11669.3 KEG13860.1 - 0.61 10.1 2.5 1.2 9.2 1.8 1.4 1 1 0 1 1 1 0 WW domain-binding protein 1 LST1 PF05083.8 KEG13860.1 - 1.1 9.3 3.6 1.2 9.1 1.8 1.7 1 1 1 2 2 2 0 LST-1 protein DUF2763 PF10961.3 KEG13862.1 - 0.12 12.8 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) DUF2962 PF11176.3 KEG13868.1 - 1.2e-28 99.6 0.1 1.2e-28 99.6 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2962) PVL_ORF50 PF07768.6 KEG13868.1 - 8.2 6.4 11.0 5.9 6.9 2.3 2.7 3 0 0 3 3 3 0 PVL ORF-50-like family Cas1_AcylT PF07779.7 KEG13869.1 - 4.9e-69 233.0 25.3 2.2e-68 230.9 17.5 1.8 1 1 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p DUF3397 PF11877.3 KEG13869.1 - 0.011 15.7 4.2 0.011 15.7 2.9 4.4 4 2 0 4 4 4 0 Protein of unknown function (DUF3397) MTHFR PF02219.12 KEG13870.1 - 4.1e-97 324.7 0.0 4.8e-97 324.5 0.0 1.0 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase RabGAP-TBC PF00566.13 KEG13871.1 - 6.7e-21 74.7 0.4 1.1e-20 74.0 0.3 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RabGAP-TBC PF00566.13 KEG13872.1 - 1.7e-05 24.3 0.0 3.7e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF1126 PF06565.7 KEG13873.1 - 8.3e-30 101.9 0.0 8.5e-12 44.3 0.0 3.5 3 0 0 3 3 3 3 Repeat of unknown function (DUF1126) EF-hand_7 PF13499.1 KEG13873.1 - 0.0022 18.0 0.4 0.37 10.9 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.1 KEG13873.1 - 0.012 15.2 0.6 2.7 7.6 0.0 2.8 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.27 KEG13873.1 - 0.039 13.2 0.0 3.1 7.3 0.0 2.8 2 0 0 2 2 2 0 EF hand Pkinase PF00069.20 KEG13874.1 - 1.8e-57 194.4 0.0 2.2e-57 194.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG13874.1 - 3.2e-33 114.8 0.0 4.3e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG13874.1 - 1e-14 54.1 0.0 7.4e-12 44.8 0.0 2.1 2 0 0 2 2 2 2 Kinase-like DZR PF12773.2 KEG13874.1 - 5.8e-05 22.8 1.4 0.00012 21.8 1.0 1.4 1 0 0 1 1 1 1 Double zinc ribbon Kdo PF06293.9 KEG13874.1 - 7e-05 21.9 0.0 0.00011 21.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-ribbon_3 PF13248.1 KEG13874.1 - 7.3e-05 21.8 1.0 0.00018 20.5 0.7 1.6 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 KEG13874.1 - 0.0012 18.2 1.0 0.003 17.0 0.7 1.6 1 0 0 1 1 1 1 zinc-ribbon domain DUF2116 PF09889.4 KEG13874.1 - 0.034 13.9 1.5 0.17 11.7 0.6 2.1 1 1 1 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) UPF0547 PF10571.4 KEG13874.1 - 0.13 11.9 2.4 0.26 11.0 1.7 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 zf-DHHC PF01529.15 KEG13874.1 - 0.14 11.5 0.1 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase Nudix_N_2 PF14803.1 KEG13874.1 - 0.15 11.7 1.9 1.4 8.6 0.0 2.6 2 0 0 2 2 2 0 Nudix N-terminal zf-dskA_traR PF01258.12 KEG13874.1 - 0.2 11.3 2.8 1.5 8.6 0.3 2.4 1 1 1 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger DUF35_N PF12172.3 KEG13874.1 - 1 9.3 4.3 2.8 7.9 3.0 1.7 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) ABC2_membrane PF01061.19 KEG13875.1 - 2.2e-34 118.4 15.8 2.2e-34 118.4 10.9 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 KEG13875.1 - 6.1e-20 71.9 0.0 1.1e-19 71.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KEG13875.1 - 6e-07 29.7 0.3 0.011 15.7 0.0 2.4 1 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 KEG13875.1 - 0.00069 18.9 0.0 0.014 14.5 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KEG13875.1 - 0.0019 18.2 0.1 0.0032 17.4 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KEG13875.1 - 0.0029 18.4 0.0 0.0057 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 KEG13875.1 - 0.0033 16.6 0.1 0.0088 15.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KEG13875.1 - 0.0047 16.8 0.0 0.014 15.3 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.7 KEG13875.1 - 0.0085 15.7 0.0 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_29 PF13555.1 KEG13875.1 - 0.0088 15.5 0.1 0.019 14.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KEG13875.1 - 0.013 14.9 0.1 0.023 14.1 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_19 PF13245.1 KEG13875.1 - 0.021 14.5 0.2 0.06 13.1 0.1 1.8 2 0 0 2 2 1 0 Part of AAA domain NTPase_1 PF03266.10 KEG13875.1 - 0.022 14.4 0.1 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 NTPase AAA_22 PF13401.1 KEG13875.1 - 0.023 14.8 0.1 0.071 13.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KEG13875.1 - 0.032 14.5 0.0 0.069 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 KEG13875.1 - 0.066 13.0 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_10 PF12846.2 KEG13875.1 - 0.084 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Gtr1_RagA PF04670.7 KEG13875.1 - 0.085 11.9 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PRK PF00485.13 KEG13875.1 - 0.087 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 KEG13875.1 - 0.11 12.8 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KEG13875.1 - 0.12 11.9 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KEG13875.1 - 0.14 12.1 0.1 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KEG13875.1 - 0.15 11.4 0.1 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.1 KEG13875.1 - 0.16 10.9 0.0 13 4.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Ribosomal_S8e PF01201.17 KEG13876.1 - 9.5e-35 119.6 14.0 1.5e-33 115.7 9.7 2.2 1 1 0 1 1 1 1 Ribosomal protein S8e DUF3746 PF12562.3 KEG13876.1 - 0.029 14.2 0.6 0.2 11.5 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3746) Mpp10 PF04006.7 KEG13878.1 - 0.00095 17.6 48.4 0.046 12.1 33.6 3.1 1 1 0 1 1 1 1 Mpp10 protein HSP90 PF00183.13 KEG13879.1 - 1.5e-144 482.3 7.6 1.3e-142 475.9 2.5 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.1 KEG13879.1 - 5.2e-09 35.8 0.0 1e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KEG13879.1 - 3.7e-05 23.4 0.0 7e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1497 PF07384.6 KEG13880.1 - 0.14 12.3 1.3 0.35 11.0 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1497) U-box PF04564.10 KEG13881.1 - 7.2e-13 48.3 0.0 2.8e-12 46.4 0.0 2.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.3 KEG13881.1 - 1.2e-06 27.9 0.0 4.6e-06 26.0 0.0 2.0 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.1 KEG13881.1 - 0.018 14.8 0.0 0.068 13.0 0.0 2.0 1 0 0 1 1 1 0 Ring finger domain DUF2684 PF10885.3 KEG13881.1 - 0.11 12.3 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2684) Band_7 PF01145.20 KEG13882.1 - 4e-21 75.7 0.0 5.7e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 KEG13882.1 - 0.11 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family Baculo_PEP_C PF04513.7 KEG13886.1 - 0.0034 17.2 0.0 0.0043 16.8 0.0 1.1 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus RE_AccI PF09545.5 KEG13887.1 - 0.15 10.5 0.0 0.22 9.9 0.0 1.1 1 0 0 1 1 1 0 AccI restriction endonuclease Nop14 PF04147.7 KEG13888.1 - 0.0037 15.2 40.9 0.0054 14.7 28.4 1.2 1 0 0 1 1 1 1 Nop14-like family CENP-T PF15511.1 KEG13888.1 - 3 7.0 36.7 5 6.2 25.4 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CDC27 PF09507.5 KEG13888.1 - 3.6 6.7 35.6 5 6.2 24.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SDA1 PF05285.7 KEG13888.1 - 6.9 5.8 45.5 11 5.2 31.5 1.2 1 0 0 1 1 1 0 SDA1 HMG_box PF00505.14 KEG13890.1 - 1.3e-40 137.4 12.1 8.8e-22 77.1 1.9 2.6 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 KEG13890.1 - 1.4e-26 92.6 13.7 9.1e-14 51.5 2.4 2.6 2 0 0 2 2 2 2 HMG-box domain DEK_C PF08766.6 KEG13890.1 - 4.5e-06 26.3 1.7 6.7e-06 25.7 0.1 2.1 2 0 0 2 2 2 1 DEK C terminal domain YABBY PF04690.8 KEG13890.1 - 0.0019 18.4 1.3 0.0039 17.4 0.9 1.5 1 0 0 1 1 1 1 YABBY protein DUF1074 PF06382.6 KEG13890.1 - 0.0051 16.8 9.8 0.18 11.7 0.2 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF1074) DUF4019 PF13211.1 KEG13890.1 - 0.035 14.3 1.2 0.1 12.8 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4019) ApoC-I PF04691.7 KEG13890.1 - 0.36 10.5 6.1 2 8.1 0.2 2.9 3 0 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) HMG_box_5 PF14887.1 KEG13890.1 - 0.48 10.2 15.4 0.44 10.3 1.1 3.3 3 1 1 4 4 4 0 HMG (high mobility group) box 5 KfrA_N PF11740.3 KEG13890.1 - 0.9 10.0 6.3 6.8 7.1 0.0 3.0 4 0 0 4 4 4 0 Plasmid replication region DNA-binding N-term RRM_5 PF13893.1 KEG13892.1 - 3e-08 33.3 0.1 4.4e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEG13892.1 - 1.2e-07 31.2 0.0 2.6e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG13892.1 - 1.5e-06 28.1 0.0 2.2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 KEG13892.1 - 0.0038 16.8 0.0 0.0044 16.6 0.0 1.1 1 0 0 1 1 1 1 Calcipressin Choline_transpo PF04515.7 KEG13893.1 - 1.5e-54 184.9 23.3 1.5e-54 184.9 16.1 2.1 3 0 0 3 3 3 1 Plasma-membrane choline transporter Herpes_UL45 PF05473.7 KEG13893.1 - 0.067 12.6 3.5 0.18 11.1 2.4 1.8 1 1 0 1 1 1 0 UL45 protein Cyt-b5 PF00173.23 KEG13894.1 - 8.5e-14 51.1 0.1 1.2e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TPR_14 PF13428.1 KEG13895.1 - 0.00016 22.0 2.1 3.1 8.6 0.2 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEG13895.1 - 0.00019 21.6 3.3 3 8.2 0.5 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat DUF4319 PF14203.1 KEG13895.1 - 0.081 12.4 0.0 0.33 10.5 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4319) TPR_8 PF13181.1 KEG13895.1 - 0.11 12.2 1.9 30 4.7 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Arf PF00025.16 KEG13896.1 - 5.7e-66 221.0 0.0 6.3e-66 220.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KEG13896.1 - 7.1e-16 57.9 0.0 8.4e-16 57.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KEG13896.1 - 1.1e-14 53.9 0.2 7.3e-11 41.3 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 KEG13896.1 - 8e-14 51.3 0.0 9.1e-14 51.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KEG13896.1 - 9.2e-13 47.8 0.0 1.1e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KEG13896.1 - 4.7e-11 43.2 0.0 6.1e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KEG13896.1 - 7.6e-10 38.7 0.0 1e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KEG13896.1 - 8.9e-06 25.2 0.0 5.5e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain cobW PF02492.14 KEG13896.1 - 0.01 15.3 0.0 0.22 10.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 KEG13896.1 - 0.026 14.7 0.0 0.06 13.5 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ArgK PF03308.11 KEG13896.1 - 0.03 13.1 0.0 0.38 9.4 0.0 2.2 2 1 0 2 2 2 0 ArgK protein PduV-EutP PF10662.4 KEG13896.1 - 0.036 13.5 0.0 0.071 12.5 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 KEG13896.1 - 0.069 13.1 0.0 0.11 12.5 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 KEG13896.1 - 0.11 13.3 0.0 0.17 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KEG13896.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KEG13896.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Vmethyltransf PF01660.12 KEG13896.1 - 0.15 10.6 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 Viral methyltransferase PhyH PF05721.8 KEG13897.1 - 1.9e-06 28.0 0.0 3.2e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Oxidored_FMN PF00724.15 KEG13898.1 - 1.3e-57 195.3 0.0 1.6e-57 195.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.9 KEG13898.1 - 4e-15 56.2 0.7 6.7e-11 42.4 0.4 3.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEG13898.1 - 4e-11 43.3 0.0 0.00022 21.3 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEG13898.1 - 3.7e-10 39.2 3.8 6.8e-08 31.8 0.0 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KEG13898.1 - 7.7e-10 39.0 1.8 4.1e-05 23.9 0.0 3.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEG13898.1 - 1.1e-09 38.1 0.3 1.6e-08 34.4 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KEG13898.1 - 3.2e-07 29.5 0.0 0.0012 17.8 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.2 KEG13898.1 - 3.7e-06 26.2 0.2 5.6e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KEG13898.1 - 4.2e-06 25.5 1.1 1.1e-05 24.1 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 KEG13898.1 - 3.1e-05 23.1 0.6 0.00073 18.7 0.0 2.3 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 KEG13898.1 - 3.6e-05 23.5 0.8 0.0082 15.9 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KEG13898.1 - 4.6e-05 22.4 0.3 0.00012 21.0 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_Gly3P_dh_N PF01210.18 KEG13898.1 - 0.00026 20.7 0.0 0.027 14.1 0.0 2.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 KEG13898.1 - 0.0004 20.7 0.8 1.6 9.1 0.1 3.0 3 0 0 3 3 2 2 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 KEG13898.1 - 0.00058 20.0 0.1 0.027 14.7 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.14 KEG13898.1 - 0.00062 18.9 0.2 0.0034 16.5 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain ApbA PF02558.11 KEG13898.1 - 0.0014 18.0 0.1 0.092 12.1 0.0 2.5 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 KEG13898.1 - 0.0034 16.3 0.1 0.0034 16.3 0.0 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 KEG13898.1 - 0.0068 16.0 1.2 0.091 12.4 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KEG13898.1 - 0.01 15.8 0.6 0.24 11.3 0.1 2.9 3 0 0 3 3 3 0 NADH(P)-binding FMO-like PF00743.14 KEG13898.1 - 0.019 13.2 0.0 0.22 9.7 0.0 2.2 1 1 1 2 2 2 0 Flavin-binding monooxygenase-like UDPG_MGDP_dh_N PF03721.9 KEG13898.1 - 0.024 14.0 0.3 0.12 11.7 0.0 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.15 KEG13898.1 - 0.025 14.6 0.9 2.3 8.3 0.1 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 KEG13898.1 - 0.052 13.3 2.1 6.2 6.6 0.2 3.3 4 0 0 4 4 3 0 ThiF family Amino_oxidase PF01593.19 KEG13898.1 - 0.065 12.2 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 KEG13898.1 - 0.075 11.6 1.0 0.22 10.1 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase TrkA_N PF02254.13 KEG13898.1 - 0.11 12.4 0.0 10 6.1 0.0 2.9 3 0 0 3 3 3 0 TrkA-N domain Saccharop_dh PF03435.13 KEG13898.1 - 0.15 10.9 0.4 0.63 8.9 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase Lycopene_cycl PF05834.7 KEG13898.1 - 0.18 10.6 0.1 0.64 8.8 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Cnd1 PF12717.2 KEG13899.1 - 2.3e-41 141.6 7.4 2.8e-36 125.0 0.0 4.8 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KEG13899.1 - 3.8e-09 35.8 8.8 0.55 10.4 0.0 7.8 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.1 KEG13899.1 - 2.1e-08 34.3 0.1 0.44 10.8 0.0 5.5 2 2 2 4 4 4 3 HEAT repeats Cnd1_N PF12922.2 KEG13899.1 - 1.7e-05 24.4 1.3 2.8e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_EZ PF13513.1 KEG13899.1 - 3e-05 24.3 0.0 0.046 14.2 0.0 4.9 5 0 0 5 5 5 1 HEAT-like repeat V-ATPase_H_C PF11698.3 KEG13899.1 - 0.023 14.6 0.6 26 4.7 0.0 3.7 3 0 0 3 3 3 0 V-ATPase subunit H Pkinase PF00069.20 KEG13900.1 - 9e-64 215.1 0.0 1.1e-63 214.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG13900.1 - 2.4e-28 98.9 0.0 2e-27 95.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase FYVE PF01363.16 KEG13900.1 - 1.2e-21 76.3 10.1 2.2e-21 75.5 7.0 1.5 1 0 0 1 1 1 1 FYVE zinc finger APH PF01636.18 KEG13900.1 - 0.0021 17.8 0.0 0.0047 16.7 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KEG13900.1 - 0.0026 16.7 0.0 0.004 16.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like IBR PF01485.16 KEG13900.1 - 0.017 14.9 3.9 0.059 13.2 2.7 1.9 1 0 0 1 1 1 0 IBR domain FYVE_2 PF02318.11 KEG13900.1 - 0.37 10.6 7.1 0.11 12.3 2.8 1.7 2 0 0 2 2 2 0 FYVE-type zinc finger HypA PF01155.14 KEG13900.1 - 6.9 6.4 8.2 4.4 7.0 2.8 2.5 2 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family CorA PF01544.13 KEG13902.1 - 4.5e-19 68.5 0.0 6.2e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Presenilin PF01080.12 KEG13903.1 - 1.1e-60 205.6 27.5 9.3e-46 156.4 8.0 2.0 1 1 0 2 2 2 2 Presenilin Wyosine_form PF08608.7 KEG13904.1 - 2.2e-17 62.9 0.0 7.1e-17 61.2 0.0 1.9 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.16 KEG13904.1 - 1.6e-15 57.6 0.0 4.5e-15 56.1 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Sld5 PF05916.6 KEG13905.1 - 0.031 14.5 0.0 0.045 14.0 0.0 1.3 1 0 0 1 1 1 0 GINS complex protein HMG_box_2 PF09011.5 KEG13907.1 - 1.6e-05 25.1 0.2 0.00063 20.0 0.0 2.5 2 0 0 2 2 2 1 HMG-box domain PDEase_I PF00233.14 KEG13908.1 - 3.4e-61 207.0 0.5 9.5e-61 205.5 0.0 1.9 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.21 KEG13908.1 - 3.5e-45 153.8 0.5 3.1e-22 79.3 0.0 3.4 3 0 0 3 3 3 2 GAF domain GAF_2 PF13185.1 KEG13908.1 - 2.8e-21 76.5 0.2 1.2e-07 32.2 0.0 3.5 3 0 0 3 3 3 3 GAF domain GAF_3 PF13492.1 KEG13908.1 - 8.2e-17 61.5 0.1 2e-08 34.3 0.0 3.5 3 0 0 3 3 3 2 GAF domain Ribosomal_L7Ae PF01248.21 KEG13909.1 - 4e-25 87.1 0.0 4.7e-25 86.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.1 KEG13909.1 - 0.00039 20.1 0.0 0.00051 19.7 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.6 KEG13909.1 - 0.00059 19.7 0.1 0.00065 19.5 0.1 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 ICE2 PF08426.5 KEG13910.1 - 0.01 14.4 0.0 0.014 14.0 0.0 1.1 1 0 0 1 1 1 0 ICE2 DUF679 PF05078.7 KEG13910.1 - 0.065 12.8 0.0 0.079 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF679) DUF4131 PF13567.1 KEG13910.1 - 0.078 12.3 0.0 0.096 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) OAD_gamma PF04277.8 KEG13910.1 - 0.77 10.1 2.5 1.1 9.6 1.8 1.3 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain GHMP_kinases_N PF00288.21 KEG13911.1 - 3.6e-10 39.7 1.8 3.6e-10 39.7 1.2 2.7 3 0 0 3 3 3 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KEG13911.1 - 0.00026 21.1 0.2 0.00026 21.1 0.2 2.2 3 0 0 3 3 3 1 GHMP kinases C terminal PCNA_N PF00705.13 KEG13912.1 - 1.1e-42 144.5 2.4 8e-42 141.7 1.3 2.2 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 KEG13912.1 - 4.6e-39 133.2 0.1 2.9e-19 69.2 0.1 2.4 2 0 0 2 2 2 2 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 KEG13912.1 - 2.5e-07 30.0 0.0 3.2e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 KEG13912.1 - 1.8e-05 23.6 0.3 0.00037 19.3 0.2 2.2 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.7 KEG13912.1 - 0.00048 19.1 0.4 0.0041 16.1 0.2 2.1 2 0 0 2 2 2 1 Hus1-like protein tRNA-synt_1c PF00749.16 KEG13913.1 - 3.9e-99 331.2 0.0 5e-99 330.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KEG13913.1 - 1.4e-39 135.5 0.0 2.2e-39 134.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain MutS_V PF00488.16 KEG13915.1 - 2.4e-68 230.0 0.0 3.8e-68 229.3 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KEG13915.1 - 3.4e-27 95.5 0.8 6.6e-27 94.6 0.5 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KEG13915.1 - 1.4e-21 76.6 0.0 4.1e-21 75.1 0.0 1.8 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.13 KEG13915.1 - 1.9e-08 34.3 0.0 4.3e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV zf-RING_2 PF13639.1 KEG13916.1 - 1.8e-09 37.2 7.1 4.4e-09 36.0 4.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KEG13916.1 - 2.7e-05 24.2 3.2 5.6e-05 23.1 2.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KEG13916.1 - 0.00012 22.0 7.2 0.00026 20.9 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KEG13916.1 - 0.0012 18.7 5.7 0.0024 17.7 3.9 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_UBOX PF13445.1 KEG13916.1 - 0.0018 17.9 4.3 0.0018 17.9 2.9 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 KEG13916.1 - 0.0032 17.1 6.3 0.0077 15.9 4.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-HC5HC2H_2 PF13832.1 KEG13916.1 - 0.0054 16.7 2.4 0.0097 15.8 1.6 1.3 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-C3HC4 PF00097.20 KEG13916.1 - 0.022 14.3 7.4 0.04 13.5 5.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H PF13771.1 KEG13916.1 - 0.029 14.4 2.6 0.052 13.7 1.8 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain Latarcin PF10279.4 KEG13917.1 - 0.076 13.2 2.1 3.5 7.8 0.1 2.4 2 0 0 2 2 2 0 Latarcin precursor LUC7 PF03194.10 KEG13917.1 - 0.44 10.0 5.3 0.49 9.8 2.9 1.6 1 1 0 1 1 1 0 LUC7 N_terminus Rotamase_2 PF13145.1 KEG13917.1 - 0.51 10.9 7.6 0.58 10.7 1.3 2.4 2 0 0 2 2 2 0 PPIC-type PPIASE domain Mis14 PF08641.7 KEG13917.1 - 5.3 7.0 10.5 0.47 10.5 3.8 1.8 2 1 0 2 2 2 0 Kinetochore protein Mis14 like TMEM164 PF14808.1 KEG13919.1 - 4e-12 45.8 9.1 5.3e-12 45.4 6.3 1.1 1 0 0 1 1 1 1 TMEM164 family PH_11 PF15413.1 KEG13920.1 - 3.3e-05 24.1 0.2 6.3e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KEG13920.1 - 0.0054 16.9 0.1 0.0083 16.3 0.1 1.2 1 0 0 1 1 1 1 PH domain zf-CCCH PF00642.19 KEG13922.1 - 1.7e-06 27.5 1.3 1.7e-06 27.5 0.9 2.6 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KEG13922.1 - 0.16 11.9 4.9 0.057 13.4 0.7 2.3 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type zf-CCCH PF00642.19 KEG13924.1 - 6e-08 32.1 4.1 6e-08 32.1 2.8 2.1 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KEG13924.1 - 0.054 13.5 0.5 0.15 12.1 0.4 1.8 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type DEAD PF00270.24 KEG13925.1 - 9.9e-42 142.3 0.1 2.1e-41 141.2 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEG13925.1 - 7.3e-23 80.2 0.0 2.2e-22 78.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Mito_carr PF00153.22 KEG13926.1 - 7.7e-45 150.5 0.5 6.1e-15 54.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein FMO-like PF00743.14 KEG13928.1 - 6.8e-29 100.4 0.0 1.3e-23 82.9 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KEG13928.1 - 2.9e-21 76.4 0.0 5.6e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEG13928.1 - 2.1e-12 47.3 0.0 6.2e-10 39.2 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KEG13928.1 - 3.3e-10 39.3 0.2 2.1e-08 33.4 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 KEG13928.1 - 1.1e-07 32.0 0.0 0.018 15.4 0.0 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEG13928.1 - 3.3e-06 27.0 0.3 1.4e-05 25.0 0.0 2.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KEG13928.1 - 5.3e-05 23.0 0.0 0.00019 21.2 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KEG13928.1 - 0.0051 15.7 0.0 0.014 14.2 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain IlvN PF07991.7 KEG13928.1 - 0.017 14.5 0.0 1 8.6 0.0 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain HI0933_like PF03486.9 KEG13928.1 - 0.018 13.5 0.5 0.051 12.0 0.2 1.8 2 0 0 2 2 2 0 HI0933-like protein DAO PF01266.19 KEG13928.1 - 0.032 13.1 0.7 3.8 6.3 0.0 3.0 4 0 0 4 4 4 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 KEG13928.1 - 0.042 14.1 0.2 0.53 10.5 0.0 2.6 3 0 0 3 3 3 0 Putative NAD(P)-binding Lycopene_cycl PF05834.7 KEG13928.1 - 0.056 12.3 0.0 0.089 11.6 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 KEG13928.1 - 0.14 11.1 0.2 3.6 6.5 0.1 2.3 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 KEG13928.1 - 0.42 9.4 1.5 0.72 8.6 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A ThiF PF00899.16 KEG13928.1 - 0.46 10.2 3.1 1 9.2 0.6 2.4 2 0 0 2 2 2 0 ThiF family AAA_2 PF07724.9 KEG13929.1 - 1.4e-39 135.7 1.1 3.3e-31 108.4 0.2 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 KEG13929.1 - 1.9e-13 50.7 0.3 4.4e-06 26.9 0.1 3.3 1 1 1 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KEG13929.1 - 1.9e-08 34.1 0.5 2.3e-05 24.1 0.0 2.8 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KEG13929.1 - 2.7e-06 27.5 0.0 0.00027 21.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KEG13929.1 - 5.1e-06 27.3 0.1 4.2e-05 24.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KEG13929.1 - 3.1e-05 24.2 0.2 8.8e-05 22.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain ClpB_D2-small PF10431.4 KEG13929.1 - 4.1e-05 23.4 0.1 0.00017 21.4 0.0 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 KEG13929.1 - 5.3e-05 23.2 0.2 0.00013 22.0 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain MCM PF00493.18 KEG13929.1 - 0.00032 19.6 0.3 0.011 14.5 0.0 2.4 2 0 0 2 2 2 1 MCM2/3/5 family Mg_chelatase PF01078.16 KEG13929.1 - 0.00039 19.6 1.1 0.002 17.3 0.1 2.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 KEG13929.1 - 0.00057 18.7 0.0 0.0011 17.7 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus Zeta_toxin PF06414.7 KEG13929.1 - 0.00067 18.8 0.1 0.0014 17.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_14 PF13173.1 KEG13929.1 - 0.00071 19.4 0.0 1.4 8.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KEG13929.1 - 0.0015 18.4 0.0 0.0081 16.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain DEAD PF00270.24 KEG13929.1 - 0.0016 17.9 0.8 0.15 11.5 0.6 2.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase RuvB_N PF05496.7 KEG13929.1 - 0.0019 17.2 0.2 0.013 14.5 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus NTPase_1 PF03266.10 KEG13929.1 - 0.0021 17.7 0.4 0.57 9.8 0.0 2.5 2 0 0 2 2 2 1 NTPase T2SE PF00437.15 KEG13929.1 - 0.01 14.7 0.0 0.02 13.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.1 KEG13929.1 - 0.015 15.2 0.5 0.11 12.4 0.2 2.6 2 2 2 4 4 4 0 AAA domain IstB_IS21 PF01695.12 KEG13929.1 - 0.016 14.6 0.0 0.037 13.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.21 KEG13929.1 - 0.026 14.0 0.1 0.071 12.5 0.0 1.7 2 0 0 2 2 1 0 Sigma-54 interaction domain ATP-synt_ab PF00006.20 KEG13929.1 - 0.026 14.0 0.0 0.058 12.8 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_tran PF00005.22 KEG13929.1 - 0.027 14.7 0.0 0.063 13.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter CPT PF07931.7 KEG13929.1 - 0.027 14.0 0.0 0.19 11.3 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein RNA_helicase PF00910.17 KEG13929.1 - 0.036 14.2 0.0 0.7 10.0 0.0 2.9 3 0 0 3 3 3 0 RNA helicase SKI PF01202.17 KEG13929.1 - 0.043 13.6 1.1 0.38 10.6 0.2 2.6 2 1 0 2 2 2 0 Shikimate kinase UPF0079 PF02367.12 KEG13929.1 - 0.051 13.2 0.0 0.22 11.1 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 OS-D PF03392.8 KEG13933.1 - 0.0035 17.2 0.1 0.0054 16.6 0.0 1.4 1 1 0 1 1 1 1 Insect pheromone-binding family, A10/OS-D Myb_DNA-binding PF00249.26 KEG13933.1 - 0.055 13.5 0.0 0.087 12.9 0.0 1.3 1 0 0 1 1 1 0 Myb-like DNA-binding domain DAN PF03045.10 KEG13933.1 - 0.063 12.6 0.4 0.08 12.3 0.2 1.2 1 0 0 1 1 1 0 DAN domain FSIP1 PF15554.1 KEG13936.1 - 0.013 14.3 0.3 0.013 14.3 0.2 2.3 2 0 0 2 2 2 0 FSIP1 family MerR-DNA-bind PF09278.6 KEG13936.1 - 0.049 14.0 2.6 1.9 8.9 0.0 2.8 2 0 0 2 2 2 0 MerR, DNA binding MIF4G PF02854.14 KEG13937.1 - 4.4e-24 85.0 0.0 6.7e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain CRM1_C PF08767.6 KEG13937.1 - 0.0022 16.9 0.0 0.005 15.7 0.0 1.5 1 0 0 1 1 1 1 CRM1 C terminal ISAV_HA PF06215.6 KEG13937.1 - 0.026 12.8 0.0 0.041 12.1 0.0 1.2 1 0 0 1 1 1 0 Infectious salmon anaemia virus haemagglutinin NAD_binding_1 PF00175.16 KEG13939.1 - 1.4e-22 80.3 0.0 2.7e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KEG13939.1 - 1.3e-15 57.2 0.0 2.1e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KEG13939.1 - 9e-05 22.4 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Lysine_decarbox PF03641.9 KEG13940.1 - 9.5e-25 86.9 0.0 1.8e-24 86.0 0.0 1.5 1 0 0 1 1 1 1 Possible lysine decarboxylase GDA1_CD39 PF01150.12 KEG13941.1 - 1.2e-52 178.9 0.0 6.8e-51 173.1 0.0 2.0 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family WD40 PF00400.27 KEG13942.1 - 3.9e-52 172.3 17.5 2.9e-10 39.6 0.0 10.0 10 0 0 10 10 10 7 WD domain, G-beta repeat eIF2A PF08662.6 KEG13942.1 - 4.6e-06 26.4 0.0 0.088 12.5 0.0 3.7 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A CPSF_A PF03178.10 KEG13942.1 - 0.0013 17.8 0.1 3.7 6.5 0.0 4.1 4 2 1 5 5 5 2 CPSF A subunit region IKI3 PF04762.7 KEG13942.1 - 0.014 13.2 0.1 0.38 8.5 0.0 2.3 1 1 0 2 2 2 0 IKI3 family ERG2_Sigma1R PF04622.7 KEG13943.1 - 1.4e-69 233.7 0.3 1.6e-69 233.4 0.2 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein LRR_4 PF12799.2 KEG13944.1 - 9.7e-18 63.3 3.1 0.0097 15.5 0.0 7.2 5 2 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEG13944.1 - 4.3e-15 53.4 8.8 0.33 11.1 0.0 9.8 8 4 1 9 9 9 5 Leucine Rich Repeat LRR_8 PF13855.1 KEG13944.1 - 1.2e-13 50.6 1.6 0.008 15.9 0.0 5.8 3 2 3 6 6 6 5 Leucine rich repeat LRR_7 PF13504.1 KEG13944.1 - 6.7e-11 40.5 13.2 0.86 10.0 0.0 9.4 10 0 0 10 10 10 4 Leucine rich repeat LRR_6 PF13516.1 KEG13944.1 - 7.7e-10 37.8 11.5 0.36 11.0 0.0 8.6 9 0 0 9 9 9 2 Leucine Rich repeat FNIP PF05725.7 KEG13944.1 - 1.2e-07 31.5 0.0 0.57 10.1 0.0 5.9 6 0 0 6 6 6 1 FNIP Repeat PH PF00169.24 KEG13945.1 - 0.00063 19.9 0.0 0.072 13.2 0.0 3.0 3 0 0 3 3 3 1 PH domain PH_8 PF15409.1 KEG13945.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain VIT1 PF01988.14 KEG13946.1 - 1.7e-27 96.2 20.4 7.2e-27 94.2 2.6 2.1 2 0 0 2 2 2 2 VIT family UDP-g_GGTase PF06427.6 KEG13947.1 - 5.6e-58 195.7 0.0 9.4e-57 191.7 0.0 2.5 2 0 0 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 KEG13947.1 - 6.5e-06 25.6 0.0 1.4e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 AAA_12 PF13087.1 KEG13948.1 - 8.2e-36 123.2 0.0 1.3e-35 122.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KEG13948.1 - 2.3e-21 76.4 0.0 1.9e-20 73.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KEG13948.1 - 8.9e-09 35.2 0.0 0.00069 19.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KEG13948.1 - 6.8e-05 22.5 2.5 0.00035 20.2 0.0 3.2 3 0 0 3 3 3 1 Part of AAA domain Viral_helicase1 PF01443.13 KEG13948.1 - 0.002 17.6 0.2 1.4 8.3 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase TrbC PF04956.8 KEG13948.1 - 0.0026 17.7 0.2 0.0094 15.9 0.1 2.0 1 0 0 1 1 1 1 TrbC/VIRB2 family PhoH PF02562.11 KEG13948.1 - 0.0056 15.9 0.0 0.035 13.3 0.0 2.2 3 0 0 3 3 3 1 PhoH-like protein AAA_22 PF13401.1 KEG13948.1 - 0.016 15.3 0.3 0.93 9.6 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA PF00004.24 KEG13948.1 - 0.058 13.5 0.3 5.5 7.2 0.0 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KEG13948.1 - 0.087 13.6 0.7 0.4 11.5 0.1 2.5 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.4 KEG13948.1 - 0.097 11.6 0.0 0.27 10.1 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) zf-CCHC PF00098.18 KEG13948.1 - 1.6 8.8 5.6 4.2 7.4 3.9 1.7 1 0 0 1 1 1 0 Zinc knuckle DUF3042 PF11240.3 KEG13948.1 - 5.6 6.8 7.0 13 5.6 4.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) adh_short PF00106.20 KEG13949.1 - 7.3e-07 29.2 0.0 1.2e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Dishevelled PF02377.10 KEG13949.1 - 0.037 14.2 1.1 7.9 6.7 0.0 3.2 3 0 0 3 3 3 0 Dishevelled specific domain Nuc_sug_transp PF04142.10 KEG13950.1 - 1.1e-24 86.9 13.7 2.7e-24 85.6 9.5 1.5 1 1 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 KEG13950.1 - 0.013 14.4 11.2 0.029 13.2 7.8 1.7 1 1 0 1 1 1 0 UAA transporter family Beta_helix PF13229.1 KEG13951.1 - 3.2e-93 309.6 84.6 1.8e-17 63.5 3.5 13.2 2 2 12 14 14 14 14 Right handed beta helix region NosD PF05048.8 KEG13951.1 - 3.1e-74 249.0 37.9 5.8e-12 45.2 3.0 13.2 4 3 9 14 14 14 14 Periplasmic copper-binding protein (NosD) HEAT PF02985.17 KEG13952.1 - 0.00096 19.0 0.1 0.13 12.3 0.1 3.4 2 0 0 2 2 2 1 HEAT repeat HEAT_EZ PF13513.1 KEG13952.1 - 0.026 15.0 1.7 30 5.2 0.0 4.5 3 1 0 3 3 3 0 HEAT-like repeat HEAT_2 PF13646.1 KEG13952.1 - 0.043 14.0 2.7 0.46 10.8 0.0 3.8 4 1 0 4 4 4 0 HEAT repeats BUD22 PF09073.5 KEG13952.1 - 0.15 11.0 0.5 0.25 10.3 0.3 1.2 1 0 0 1 1 1 0 BUD22 RRN3 PF05327.6 KEG13952.1 - 0.18 9.8 4.4 0.25 9.3 2.5 1.6 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 WD40 PF00400.27 KEG13954.1 - 0.00011 21.9 0.4 0.00038 20.2 0.1 1.9 2 0 0 2 2 2 1 WD domain, G-beta repeat PQQ_2 PF13360.1 KEG13954.1 - 0.012 15.0 0.0 0.017 14.5 0.0 1.3 1 1 0 1 1 1 0 PQQ-like domain Mig-14 PF07395.6 KEG13954.1 - 0.1 11.6 0.0 0.11 11.4 0.0 1.0 1 0 0 1 1 1 0 Mig-14 FHA PF00498.21 KEG13955.1 - 0.00038 20.5 0.0 0.00089 19.3 0.0 1.5 1 0 0 1 1 1 1 FHA domain DUF4379 PF14311.1 KEG13956.1 - 7.2e-30 102.5 33.9 1.1e-11 44.4 0.5 5.2 4 2 1 5 5 5 4 Domain of unknown function (DUF4379) NTF2 PF02136.15 KEG13958.1 - 2.1e-15 57.1 0.0 2.4e-15 56.9 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain ParBc PF02195.13 KEG13958.1 - 0.14 12.2 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 ParB-like nuclease domain Pkinase PF00069.20 KEG13959.1 - 3.3e-58 196.8 0.0 3.5e-57 193.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG13959.1 - 5.4e-33 114.1 0.1 3.8e-24 85.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KEG13959.1 - 1.7e-05 24.6 0.6 0.071 12.8 0.5 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 KEG13959.1 - 0.0014 17.7 0.5 0.0029 16.6 0.0 1.8 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 KEG13959.1 - 0.01 14.9 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KEG13959.1 - 0.053 12.3 0.0 0.08 11.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 KEG13959.1 - 0.053 12.3 0.0 0.083 11.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Thioredoxin PF00085.15 KEG13960.1 - 6.8e-13 48.2 0.0 8.1e-13 47.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin PF00085.15 KEG13961.1 - 2.5e-21 75.3 0.0 3.3e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin ERp29_N PF07912.8 KEG13961.1 - 0.00012 21.9 0.2 0.00019 21.3 0.1 1.2 1 0 0 1 1 1 1 ERp29, N-terminal domain Thioredoxin_2 PF13098.1 KEG13961.1 - 0.00076 19.6 0.3 0.0056 16.8 0.2 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KEG13961.1 - 0.00081 19.4 0.1 0.03 14.4 0.1 2.2 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_6 PF13848.1 KEG13961.1 - 0.0011 18.7 0.0 0.0032 17.2 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain ADH_N_assoc PF13823.1 KEG13961.1 - 0.029 14.0 1.1 0.22 11.2 0.1 2.4 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-associated Thioredoxin_7 PF13899.1 KEG13961.1 - 0.052 13.5 0.0 0.08 12.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like NB-ARC PF00931.17 KEG13963.1 - 0.00097 18.0 0.0 0.0016 17.3 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain RAP1 PF07218.6 KEG13963.1 - 0.054 11.5 0.4 0.08 11.0 0.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF1637 PF07847.7 KEG13965.1 - 1.4e-35 122.4 0.0 1.6e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) Cupin_2 PF07883.6 KEG13965.1 - 0.00058 19.3 0.0 0.068 12.6 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Peptidase_C1 PF00112.18 KEG13966.1 - 7.4e-59 199.2 5.4 1.1e-58 198.7 3.8 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 KEG13966.1 - 1.9e-13 50.4 1.1 3.6e-13 49.5 0.7 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 KEG13966.1 - 0.0029 16.1 0.5 0.0076 14.8 0.1 1.7 2 0 0 2 2 2 1 Peptidase C1-like family FAD_binding_3 PF01494.14 KEG13967.1 - 1.2e-11 44.3 0.1 4.4e-11 42.4 0.0 2.1 2 1 0 2 2 2 1 FAD binding domain SE PF08491.5 KEG13967.1 - 0.0034 16.2 0.0 0.006 15.4 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase EnY2 PF10163.4 KEG13968.1 - 0.0024 17.7 0.0 0.0029 17.5 0.0 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 DUF2956 PF11169.3 KEG13969.1 - 0.17 11.8 1.3 2.3 8.2 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2956) MAS20 PF02064.10 KEG13969.1 - 0.31 10.9 0.1 0.31 10.9 0.1 1.9 2 0 0 2 2 2 0 MAS20 protein import receptor Cir_N PF10197.4 KEG13969.1 - 5.3 7.1 9.0 10 6.2 6.2 1.5 1 0 0 1 1 1 0 N-terminal domain of CBF1 interacting co-repressor CIR Myc_N PF01056.13 KEG13970.1 - 3.7e-06 26.3 4.3 7.3e-06 25.3 3.0 1.5 1 0 0 1 1 1 1 Myc amino-terminal region SR-25 PF10500.4 KEG13970.1 - 0.00093 18.7 7.3 0.0022 17.5 5.0 1.6 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Na_trans_assoc PF06512.8 KEG13970.1 - 0.014 15.3 3.9 0.023 14.6 2.7 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated TLP-20 PF06088.6 KEG13970.1 - 0.12 12.0 0.8 0.23 11.1 0.5 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) PBP1_TM PF14812.1 KEG13970.1 - 0.47 10.7 8.8 2.3 8.5 6.1 2.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.9 KEG13970.1 - 1.1 7.1 6.0 1.6 6.6 4.2 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 KEG13970.1 - 2.4 7.3 10.2 3.8 6.6 7.1 1.2 1 0 0 1 1 1 0 NOA36 protein zf-C2H2_4 PF13894.1 KEG13970.1 - 4 8.0 5.9 2.4 8.7 1.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger FAM176 PF14851.1 KEG13970.1 - 4.5 6.9 6.7 12 5.5 4.6 1.7 1 0 0 1 1 1 0 FAM176 family Nucleoplasmin PF03066.10 KEG13970.1 - 6.6 6.2 11.5 14 5.1 7.9 1.5 1 0 0 1 1 1 0 Nucleoplasmin AbiH PF14253.1 KEG13971.1 - 0.12 11.9 0.1 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH CENP-F_leu_zip PF10473.4 KEG13971.1 - 0.37 10.6 3.5 1.3 8.9 2.0 1.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prenyltransf PF01255.14 KEG13972.1 - 2.4e-53 180.5 0.2 5.7e-51 172.7 0.0 2.1 2 0 0 2 2 2 2 Putative undecaprenyl diphosphate synthase WD40 PF00400.27 KEG13973.1 - 4.2e-13 48.6 17.8 0.0016 18.2 0.1 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat PQQ_2 PF13360.1 KEG13973.1 - 0.00097 18.6 0.0 0.0018 17.8 0.0 1.5 1 0 0 1 1 1 1 PQQ-like domain CLTH PF10607.4 KEG13973.1 - 0.034 13.8 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Hira PF07569.6 KEG13973.1 - 0.04 13.1 0.2 12 4.9 0.0 3.2 2 1 1 3 3 3 0 TUP1-like enhancer of split Atg8 PF02991.11 KEG13974.1 - 3.4e-31 107.2 0.0 4.1e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 KEG13974.1 - 1.1e-05 25.4 0.0 1.4e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 APG5 PF04106.7 KEG13974.1 - 0.014 14.9 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg5 Atg8 PF02991.11 KEG13975.1 - 4.2e-42 142.3 0.0 4.8e-42 142.1 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 KEG13975.1 - 2.2e-09 37.3 0.0 3e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 APG5 PF04106.7 KEG13975.1 - 0.0065 15.9 0.0 0.0078 15.7 0.0 1.3 1 1 0 1 1 1 1 Autophagy protein Apg5 MLANA PF14991.1 KEG13976.1 - 0.0035 17.3 0.0 0.0073 16.3 0.0 1.4 1 0 0 1 1 1 1 Protein melan-A SKG6 PF08693.5 KEG13976.1 - 0.014 14.7 0.2 0.026 13.8 0.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain L_HGMIC_fpl PF10242.4 KEG13976.1 - 0.021 14.8 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein TIG PF01833.19 KEG13976.1 - 0.046 13.7 0.2 0.11 12.5 0.2 1.6 1 0 0 1 1 1 0 IPT/TIG domain DUF3827 PF12877.2 KEG13976.1 - 0.054 11.6 0.0 0.069 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF1191 PF06697.7 KEG13976.1 - 0.13 11.0 0.0 0.21 10.3 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1191) EphA2_TM PF14575.1 KEG13976.1 - 0.15 12.4 0.2 0.24 11.8 0.1 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ADH_N PF08240.7 KEG13977.1 - 2.6e-25 88.2 0.1 7.8e-25 86.7 0.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEG13977.1 - 2.3e-21 75.6 0.2 3.9e-21 74.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEG13977.1 - 0.00025 21.9 0.0 0.00045 21.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 KEG13977.1 - 0.00068 19.6 0.4 0.0016 18.4 0.1 1.7 2 0 0 2 2 2 1 TrkA-N domain Gp_dh_N PF00044.19 KEG13977.1 - 0.0066 16.4 0.3 0.045 13.7 0.1 2.3 2 1 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Ubie_methyltran PF01209.13 KEG13977.1 - 0.1 11.7 0.1 0.18 10.8 0.1 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family SET PF00856.23 KEG13978.1 - 1.4e-13 51.4 0.0 9.7e-12 45.4 0.0 3.1 2 1 0 2 2 2 1 SET domain PGC7_Stella PF15549.1 KEG13978.1 - 0.069 13.1 0.8 0.15 12.0 0.6 1.5 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain FAD_binding_7 PF03441.9 KEG13981.1 - 6.9e-100 333.8 3.3 1.1e-99 333.2 2.3 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 KEG13981.1 - 7.9e-32 110.2 1.1 3.8e-31 108.0 0.0 2.4 2 1 0 2 2 2 1 DNA photolyase SUZ-C PF12901.2 KEG13983.1 - 0.48 10.1 0.2 0.48 10.1 0.1 1.9 2 0 0 2 2 2 0 SUZ-C motif DUF2209 PF09974.4 KEG13986.1 - 0.12 12.4 0.1 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) CbtA PF09490.5 KEG13989.1 - 0.1 11.9 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) DUF2537 PF10801.3 KEG13990.1 - 0.43 10.7 7.8 0.081 13.0 2.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2537) MutS_V PF00488.16 KEG13991.1 - 3.3e-85 285.2 0.0 5.7e-85 284.4 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KEG13991.1 - 7e-32 110.8 2.0 7e-32 110.8 1.4 1.9 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 KEG13991.1 - 3.6e-19 68.7 3.1 7.5e-19 67.6 2.2 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.1 KEG13991.1 - 0.066 12.7 0.1 0.27 10.8 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.1 KEG13991.1 - 0.21 11.8 1.8 2.9 8.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Abhydrolase_5 PF12695.2 KEG13992.1 - 4.6e-23 81.5 0.0 6.1e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEG13992.1 - 2.2e-17 63.7 0.0 1e-11 45.1 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEG13992.1 - 3.6e-13 49.6 0.0 2.8e-10 40.1 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KEG13992.1 - 1.4e-08 34.2 0.0 4.4e-08 32.5 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KEG13992.1 - 7.2e-07 28.8 0.0 0.0069 15.8 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 KEG13992.1 - 1.3e-06 28.1 0.0 2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KEG13992.1 - 2.2e-05 24.2 0.0 4.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Esterase PF00756.15 KEG13992.1 - 0.004 16.6 0.0 0.12 11.7 0.0 2.3 1 1 1 2 2 2 1 Putative esterase AXE1 PF05448.7 KEG13992.1 - 0.01 14.3 0.1 1.2 7.5 0.0 2.7 2 1 0 2 2 2 0 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 KEG13992.1 - 0.011 15.5 0.0 2.9 7.5 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 KEG13992.1 - 0.011 14.9 0.0 2.9 7.1 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family FSH1 PF03959.8 KEG13992.1 - 0.039 13.4 0.0 0.14 11.5 0.0 1.9 1 1 1 2 2 2 0 Serine hydrolase (FSH1) LIP PF03583.9 KEG13992.1 - 0.13 11.4 0.2 1.3 8.1 0.0 2.4 2 1 0 2 2 2 0 Secretory lipase DUF4586 PF15239.1 KEG13993.1 - 0.04 13.4 0.0 0.065 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4586) WD40 PF00400.27 KEG13995.1 - 2.9e-15 55.4 1.4 7.5e-07 28.7 0.0 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat Fe_hyd_lg_C PF02906.9 KEG13997.1 - 1.7e-67 227.6 0.0 2.4e-67 227.2 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain PDZ_2 PF13180.1 KEG13998.1 - 4.6e-06 26.4 0.0 1.1e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Polysacc_lyase PF14099.1 KEG13998.1 - 0.0038 16.9 0.0 0.0074 15.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide lyase PDZ PF00595.19 KEG13998.1 - 0.004 17.3 0.0 0.0099 16.0 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KEG13999.1 - 1.3e-06 28.1 0.0 4.5e-06 26.4 0.0 1.9 1 1 0 2 2 2 1 PDZ domain PDZ PF00595.19 KEG13999.1 - 9.2e-05 22.5 0.0 0.00016 21.7 0.0 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Ank PF00023.25 KEG14001.1 - 0.0011 18.6 0.1 0.0086 15.8 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 KEG14001.1 - 0.0033 17.7 0.0 0.0058 16.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TT_ORF2 PF02957.10 KEG14001.1 - 0.012 16.3 8.3 0.012 16.3 5.8 2.0 2 0 0 2 2 2 0 TT viral ORF2 ANAPC15 PF15243.1 KEG14001.1 - 0.3 11.1 26.5 0.041 13.9 8.5 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 FYDLN_acid PF09538.5 KEG14001.1 - 3.6 8.2 25.1 5.7 7.5 11.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) YscO PF07321.7 KEG14001.1 - 5.6 6.7 26.2 0.042 13.6 8.1 2.2 2 0 0 2 2 2 0 Type III secretion protein YscO Nop25 PF09805.4 KEG14001.1 - 6.8 6.7 22.1 10 6.1 9.3 2.2 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Plasmid_stab_B PF10784.4 KEG14002.1 - 0.11 12.1 0.6 0.45 10.1 0.0 2.3 2 0 0 2 2 2 0 Plasmid stability protein PTPLA PF04387.9 KEG14003.1 - 1.9e-59 199.7 6.8 2.4e-59 199.4 4.7 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA P16-Arc PF04699.9 KEG14004.1 - 1.1e-12 48.1 0.0 1.3e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Histone PF00125.19 KEG14005.1 - 9.3e-18 64.1 0.6 1.2e-17 63.7 0.4 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KEG14005.1 - 0.0049 16.8 0.3 0.011 15.8 0.2 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone GMP_synt_C PF00958.17 KEG14005.1 - 0.16 11.7 0.8 0.24 11.1 0.5 1.4 1 1 0 1 1 1 0 GMP synthase C terminal domain Mito_carr PF00153.22 KEG14006.1 - 2.3e-48 161.8 8.3 5.5e-16 58.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Glutaredoxin PF00462.19 KEG14008.1 - 8.7e-14 51.2 0.1 1.4e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin MCM PF00493.18 KEG14009.1 - 1.4e-99 333.0 0.0 1.9e-99 332.6 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family AAA_5 PF07728.9 KEG14009.1 - 2.9e-09 36.7 0.0 5e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KEG14009.1 - 1.5e-05 24.2 1.0 0.12 11.4 0.2 2.7 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KEG14009.1 - 0.00096 18.7 0.0 0.0029 17.2 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 KEG14009.1 - 0.025 14.7 0.0 0.088 13.0 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KEG14009.1 - 0.085 11.8 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus DUF4012 PF13196.1 KEG14009.1 - 0.1 12.7 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4012) Ribosomal_S11 PF00411.14 KEG14010.1 - 0.047 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S11 SAP25 PF15476.1 KEG14010.1 - 0.059 12.8 1.9 0.11 11.9 1.3 1.3 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP25 DUF2170 PF09938.4 KEG14010.1 - 0.15 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2170) Pyr_redox_2 PF07992.9 KEG14011.1 - 7.6e-35 120.6 0.0 1.4e-34 119.7 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KEG14011.1 - 1.4e-26 92.7 0.0 2.4e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 KEG14011.1 - 4e-21 75.1 0.2 4.2e-17 62.3 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KEG14011.1 - 2.2e-06 26.7 0.8 0.014 14.2 0.3 3.0 3 0 0 3 3 3 2 FAD binding domain HI0933_like PF03486.9 KEG14011.1 - 0.00019 20.0 1.0 0.077 11.4 0.2 3.1 4 0 0 4 4 4 2 HI0933-like protein Pyr_redox_3 PF13738.1 KEG14011.1 - 0.00083 19.4 0.4 0.96 9.4 0.2 3.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEG14011.1 - 0.0083 15.0 0.1 0.12 11.2 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.17 KEG14011.1 - 0.027 13.3 2.1 0.029 13.2 0.4 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A PALP PF00291.20 KEG14011.1 - 0.077 12.2 0.1 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme FAD_oxidored PF12831.2 KEG14011.1 - 0.092 11.7 0.1 0.56 9.2 0.1 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase DEAD PF00270.24 KEG14012.1 - 1.2e-40 138.8 0.0 2.6e-40 137.6 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEG14012.1 - 5.8e-21 74.1 0.0 1.4e-20 72.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEG14012.1 - 0.00016 21.5 0.0 0.0016 18.3 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Tim44 PF04280.10 KEG14014.1 - 0.062 13.2 0.0 70 3.3 0.0 3.7 4 0 0 4 4 4 0 Tim44-like domain Pkinase PF00069.20 KEG14015.1 - 2.4e-68 230.1 0.0 4.9e-68 229.0 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG14015.1 - 3e-49 167.4 0.0 5e-49 166.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase MORN PF02493.15 KEG14015.1 - 3.2e-41 136.6 42.6 7.8e-08 31.6 0.3 8.5 8 0 0 8 8 8 8 MORN repeat Kinase-like PF14531.1 KEG14015.1 - 0.00035 19.6 0.0 0.0015 17.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 KEG14015.1 - 0.03 13.6 0.0 2.1 7.6 0.0 2.2 1 1 1 2 2 2 0 RIO1 family ICEA PF05315.6 KEG14015.1 - 0.11 11.8 0.5 0.39 9.9 0.1 2.0 2 0 0 2 2 2 0 ICEA Protein SMC_N PF02463.14 KEG14016.1 - 3.5e-60 202.9 2.6 3.7e-59 199.6 1.8 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KEG14016.1 - 1.9e-16 60.1 1.3 5.2e-16 58.6 0.2 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KEG14016.1 - 5.1e-15 56.1 0.2 1e-06 28.9 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 KEG14016.1 - 9.5e-13 48.9 10.8 9.5e-13 48.9 7.5 5.1 2 2 1 3 3 3 1 AAA domain AAA_15 PF13175.1 KEG14016.1 - 4e-05 22.8 0.2 0.0018 17.4 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.1 KEG14016.1 - 7.7e-05 22.1 0.0 0.00018 20.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KEG14016.1 - 0.074 13.3 0.0 0.074 13.3 0.0 5.2 2 2 2 4 4 4 0 ABC transporter Reo_sigmaC PF04582.7 KEG14016.1 - 0.86 8.7 13.3 10 5.1 0.1 4.3 2 2 3 5 5 5 0 Reovirus sigma C capsid protein TPR_11 PF13414.1 KEG14017.1 - 6.7e-24 83.3 14.6 7.7e-10 38.2 1.6 6.5 5 1 2 7 7 7 4 TPR repeat TPR_2 PF07719.12 KEG14017.1 - 3.2e-19 67.2 24.0 3.6e-06 26.4 0.2 9.5 10 1 0 10 10 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 KEG14017.1 - 2.7e-18 66.0 1.1 3.2e-06 27.3 0.0 6.0 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEG14017.1 - 2e-16 58.9 15.6 0.00096 19.5 0.1 8.4 6 2 3 9 9 9 4 Tetratricopeptide repeat TPR_1 PF00515.23 KEG14017.1 - 6.7e-15 53.9 14.3 5.9e-06 25.6 0.5 7.7 9 1 0 9 9 9 3 Tetratricopeptide repeat Apc3 PF12895.2 KEG14017.1 - 8.4e-15 54.6 12.6 4.4e-11 42.7 0.1 6.2 4 2 4 8 8 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 KEG14017.1 - 3.1e-14 53.1 19.7 2.4e-05 24.8 0.1 7.1 4 2 4 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.1 KEG14017.1 - 2.1e-13 49.3 5.2 0.001 19.0 0.0 7.9 7 2 1 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.1 KEG14017.1 - 3.8e-10 38.7 0.4 0.00048 19.7 0.3 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 KEG14017.1 - 7.2e-10 38.6 25.0 0.0045 16.8 2.2 7.2 4 1 3 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 KEG14017.1 - 9.6e-08 31.2 4.2 0.026 14.3 0.1 6.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 KEG14017.1 - 1.2e-07 31.7 14.2 0.19 12.2 0.1 8.0 10 0 0 10 10 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 KEG14017.1 - 5.2e-06 26.2 12.1 0.00069 19.4 0.5 5.4 3 1 3 6 6 6 1 Tetratricopeptide repeat TPR_20 PF14561.1 KEG14017.1 - 0.0014 18.6 0.6 0.0092 16.0 0.0 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_3 PF07720.7 KEG14017.1 - 0.045 13.5 2.0 1 9.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat NARP1 PF12569.3 KEG14017.1 - 0.058 12.1 1.6 0.54 8.9 0.1 2.2 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 TPR_4 PF07721.9 KEG14017.1 - 0.81 10.2 20.5 4.1 8.1 0.3 6.4 7 0 0 7 7 5 0 Tetratricopeptide repeat BTAD PF03704.12 KEG14017.1 - 4.7 7.4 22.2 0.14 12.4 2.6 4.5 5 1 0 5 5 5 0 Bacterial transcriptional activator domain TPR_10 PF13374.1 KEG14017.1 - 10 6.2 20.4 0.37 10.8 0.4 5.7 6 1 1 7 7 6 0 Tetratricopeptide repeat Tctex-1 PF03645.8 KEG14018.1 - 8.1e-25 86.6 0.1 9e-25 86.4 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family Metallophos PF00149.23 KEG14019.1 - 0.00058 19.3 0.2 0.0095 15.3 0.0 2.4 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Polysacc_syn_2C PF08485.5 KEG14019.1 - 0.098 12.1 0.1 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein C-terminal Abhydrolase_9_N PF15420.1 KEG14020.1 - 0.28 10.9 3.7 5.5 6.6 0.2 2.5 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Pkinase PF00069.20 KEG14023.1 - 3.6e-63 213.1 0.0 4.6e-63 212.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG14023.1 - 3.6e-43 147.4 0.0 4.9e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG14023.1 - 1.2e-09 37.5 0.0 1.9e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH PF00169.24 KEG14023.1 - 4.5e-08 33.2 0.0 7.7e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 KEG14023.1 - 1e-07 32.1 0.1 2.1e-06 27.8 0.0 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.1 KEG14023.1 - 0.017 15.3 0.9 3.7 7.8 0.0 2.8 2 1 1 3 3 3 0 Pleckstrin homology domain DUF4407 PF14362.1 KEG14024.1 - 0.13 11.2 5.5 0.12 11.3 1.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Robl_LC7 PF03259.12 KEG14025.1 - 3.2e-09 36.2 0.1 4.1e-09 35.8 0.1 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain GAS PF13851.1 KEG14028.1 - 0.0028 16.8 21.8 0.0028 16.8 15.1 6.5 4 1 3 7 7 7 2 Growth-arrest specific micro-tubule binding DUF1981 PF09324.5 KEG14033.1 - 0.0035 16.8 0.1 0.065 12.7 0.0 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF1981) HEAT PF02985.17 KEG14033.1 - 0.031 14.3 3.1 9.7 6.5 0.2 3.5 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.1 KEG14034.1 - 0.034 14.6 0.5 0.64 10.5 0.0 3.6 3 0 0 3 3 3 0 HEAT-like repeat Exonuc_V_gamma PF04257.9 KEG14034.1 - 0.23 9.4 0.1 0.35 8.8 0.1 1.1 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit HEAT PF02985.17 KEG14035.1 - 0.053 13.6 0.1 0.46 10.6 0.0 2.3 3 0 0 3 3 3 0 HEAT repeat DUF3978 PF13123.1 KEG14035.1 - 0.1 11.9 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3978) HEAT_EZ PF13513.1 KEG14036.1 - 0.0013 19.1 0.5 0.0029 18.0 0.3 1.6 1 0 0 1 1 1 1 HEAT-like repeat HEAT_2 PF13646.1 KEG14036.1 - 0.0034 17.6 0.0 0.0082 16.4 0.0 1.6 1 0 0 1 1 1 1 HEAT repeats HEAT PF02985.17 KEG14036.1 - 0.011 15.7 0.1 3.7 7.8 0.0 2.9 3 0 0 3 3 3 0 HEAT repeat DnaJ PF00226.26 KEG14038.1 - 2.4e-20 72.0 0.1 3.8e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain DUF4173 PF13777.1 KEG14038.1 - 0.15 11.3 0.3 0.21 10.8 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4173) Peptidase_M16 PF00675.15 KEG14039.1 - 2e-31 108.7 0.0 4.5e-31 107.6 0.0 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KEG14039.1 - 1.4e-09 37.9 0.0 5.7e-05 22.8 0.0 2.8 2 0 0 2 2 2 2 Peptidase M16 inactive domain CENP-B_dimeris PF09026.5 KEG14039.1 - 9 6.6 9.1 32 4.8 3.8 3.0 3 0 0 3 3 3 0 Centromere protein B dimerisation domain BTB_2 PF02214.17 KEG14040.1 - 0.001 19.2 0.0 0.0025 17.9 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain SPRY PF00622.23 KEG14040.1 - 0.0036 17.3 0.0 0.0064 16.5 0.0 1.3 1 0 0 1 1 1 1 SPRY domain Snapin_Pallidin PF14712.1 KEG14041.1 - 0.022 15.0 0.0 0.039 14.2 0.0 1.3 1 0 0 1 1 1 0 Snapin/Pallidin DUF948 PF06103.6 KEG14041.1 - 0.035 13.9 1.9 0.36 10.7 1.3 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) PgaD PF13994.1 KEG14041.1 - 0.11 11.9 0.7 0.19 11.2 0.1 1.6 2 0 0 2 2 2 0 PgaD-like protein P16-Arc PF04699.9 KEG14041.1 - 0.25 11.3 3.0 0.7 9.8 0.1 2.4 2 1 0 2 2 2 0 ARP2/3 complex 16 kDa subunit (p16-Arc) Adap_comp_sub PF00928.16 KEG14042.1 - 3.6e-53 180.3 0.0 4.7e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KEG14042.1 - 7.9e-05 22.4 0.3 0.00016 21.3 0.0 1.7 2 0 0 2 2 2 1 Clathrin adaptor complex small chain NUDIX_2 PF13869.1 KEG14047.1 - 0.035 13.4 0.0 0.048 12.9 0.0 1.1 1 0 0 1 1 1 0 Nucleotide hydrolase WD40 PF00400.27 KEG14048.1 - 1.9e-09 37.0 0.3 0.00017 21.3 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat Ank_2 PF12796.2 KEG14049.1 - 9.4e-40 134.8 3.3 1e-09 38.5 0.0 10.5 7 3 4 11 11 11 5 Ankyrin repeats (3 copies) Ank PF00023.25 KEG14049.1 - 1e-25 88.1 29.4 2.7e-05 23.7 0.0 14.2 14 0 0 14 14 14 6 Ankyrin repeat Ank_4 PF13637.1 KEG14049.1 - 1.1e-19 70.4 15.4 1.1e-06 29.0 0.1 9.4 9 2 2 12 12 12 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEG14049.1 - 6.2e-16 58.0 20.5 0.0003 20.9 0.0 10.3 10 1 1 11 11 11 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEG14049.1 - 1.8e-13 49.2 29.8 0.017 15.2 0.0 13.3 15 0 0 15 15 15 4 Ankyrin repeat SPRY PF00622.23 KEG14049.1 - 2.2e-06 27.7 0.0 6e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 SPRY domain vATP-synt_E PF01991.13 KEG14049.1 - 0.017 14.3 3.2 0.68 9.1 3.8 2.3 2 0 0 2 2 2 0 ATP synthase (E/31 kDa) subunit NQRA PF05896.6 KEG14049.1 - 0.46 9.6 0.1 1.1 8.4 0.1 1.5 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) Topoisom_I_N PF02919.10 KEG14049.1 - 1.2 8.3 0.0 4 6.6 0.0 1.8 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment PCI PF01399.22 KEG14050.1 - 1.4e-08 34.9 0.0 4.6e-08 33.3 0.0 1.9 2 0 0 2 2 2 1 PCI domain ABC_sub_bind PF04392.7 KEG14050.1 - 0.089 11.7 0.0 11 4.8 0.0 2.2 2 0 0 2 2 2 0 ABC transporter substrate binding protein Mito_carr PF00153.22 KEG14051.1 - 4.4e-55 183.3 3.4 1.5e-17 63.0 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 KEG14051.1 - 0.016 15.2 1.2 8.8 6.3 0.0 4.1 4 1 0 4 4 4 0 Tim17/Tim22/Tim23/Pmp24 family DUF1664 PF07889.7 KEG14052.1 - 0.0017 18.1 9.5 0.37 10.6 0.7 4.2 4 0 0 4 4 4 2 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 KEG14052.1 - 0.012 15.8 10.4 0.018 15.2 1.4 3.9 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Cep57_MT_bd PF06657.8 KEG14052.1 - 0.012 15.5 9.7 0.099 12.6 0.0 4.2 4 0 0 4 4 3 0 Centrosome microtubule-binding domain of Cep57 DivIC PF04977.10 KEG14052.1 - 0.02 14.3 10.1 4.5 6.8 0.0 4.3 3 1 1 4 4 4 0 Septum formation initiator DUF2205 PF10224.4 KEG14052.1 - 0.049 13.2 4.7 4.5 6.9 0.3 3.2 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) V_ATPase_I PF01496.14 KEG14052.1 - 0.14 10.0 10.2 0.47 8.2 0.2 2.5 2 1 0 2 2 2 0 V-type ATPase 116kDa subunit family DivIVA PF05103.8 KEG14052.1 - 0.28 11.2 22.3 0.058 13.4 0.6 5.3 4 1 1 5 5 5 0 DivIVA protein DUF342 PF03961.8 KEG14052.1 - 0.6 8.4 12.9 4.9 5.4 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF342) Snapin_Pallidin PF14712.1 KEG14052.1 - 0.84 9.9 16.1 0.4 11.0 0.2 4.2 5 0 0 5 5 5 0 Snapin/Pallidin DUF948 PF06103.6 KEG14052.1 - 2.6 7.9 8.4 2.2 8.2 1.1 3.9 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF4404 PF14357.1 KEG14052.1 - 5.1 7.5 14.2 9.4 6.7 1.0 4.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4404) COG2 PF06148.6 KEG14052.1 - 5.2 6.9 14.0 1.3 8.8 0.2 4.2 5 0 0 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 CorA PF01544.13 KEG14052.1 - 7.3 5.5 9.3 3.5 6.5 0.2 2.7 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Prefoldin_2 PF01920.15 KEG14052.1 - 8.8 6.1 21.2 6.8 6.5 0.2 5.1 5 0 0 5 5 5 0 Prefoldin subunit Prefoldin PF02996.12 KEG14052.1 - 9.4 5.9 15.2 11 5.6 0.4 4.8 5 0 0 5 5 5 0 Prefoldin subunit APC10 PF03256.11 KEG14053.1 - 3.3e-50 170.3 0.0 5.8e-50 169.5 0.0 1.3 1 1 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Spt5_N PF11942.3 KEG14053.1 - 0.42 11.2 4.4 0.71 10.5 3.1 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DAGK_cat PF00781.19 KEG14055.1 - 3.5e-12 45.8 0.1 1.3e-05 24.6 0.1 3.9 2 1 0 2 2 2 2 Diacylglycerol kinase catalytic domain Pkinase PF00069.20 KEG14057.1 - 7e-42 143.3 0.0 8.5e-42 143.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG14057.1 - 2.5e-30 105.4 0.0 3.2e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEG14057.1 - 0.00049 19.8 0.1 0.00081 19.1 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KEG14057.1 - 0.0044 16.0 0.0 0.0079 15.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 KEG14057.1 - 0.017 13.9 0.8 0.024 13.4 0.5 1.4 1 1 0 1 1 1 0 Poxvirus serine/threonine protein kinase AAA PF00004.24 KEG14058.1 - 6.4e-40 136.4 0.0 1.5e-39 135.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 KEG14058.1 - 6.2e-23 80.4 0.0 2.6e-22 78.4 0.0 2.1 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 KEG14058.1 - 4.8e-21 74.4 2.7 1.4e-20 72.9 1.9 1.9 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_2 PF07724.9 KEG14058.1 - 1.2e-06 28.5 0.0 3.5e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 KEG14058.1 - 3.9e-05 24.4 0.1 0.00024 21.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KEG14058.1 - 4.4e-05 22.9 0.2 0.097 12.0 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.9 KEG14058.1 - 8.9e-05 22.2 0.1 0.0014 18.3 0.1 2.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KEG14058.1 - 0.00014 21.7 0.0 0.0003 20.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KEG14058.1 - 0.00025 21.2 0.5 0.0091 16.1 0.1 2.6 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 KEG14058.1 - 0.00082 19.2 0.0 0.0022 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KEG14058.1 - 0.00082 18.8 0.0 0.0017 17.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 KEG14058.1 - 0.0033 16.4 0.0 0.0082 15.2 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 KEG14058.1 - 0.004 16.7 0.0 0.01 15.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEG14058.1 - 0.0051 16.8 0.1 0.11 12.5 0.0 2.4 2 1 1 3 3 2 1 AAA ATPase domain TIP49 PF06068.8 KEG14058.1 - 0.0066 15.2 0.2 0.015 14.0 0.0 1.7 2 0 0 2 2 2 1 TIP49 C-terminus USP8_dimer PF08969.6 KEG14058.1 - 0.007 16.3 4.4 0.007 16.3 3.1 1.8 2 0 0 2 2 2 1 USP8 dimerisation domain DUF815 PF05673.8 KEG14058.1 - 0.0098 14.8 0.0 0.018 14.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 KEG14058.1 - 0.014 14.5 0.0 0.034 13.3 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.13 KEG14058.1 - 0.015 14.8 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.7 KEG14058.1 - 0.018 14.1 0.0 0.078 12.0 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.17 KEG14058.1 - 0.025 14.7 0.0 0.056 13.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.21 KEG14058.1 - 0.026 13.9 0.0 0.067 12.6 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 KEG14058.1 - 0.032 13.9 2.1 3.7 7.1 0.0 2.9 2 1 1 3 3 3 0 Archaeal ATPase AAA_18 PF13238.1 KEG14058.1 - 0.036 14.3 0.2 0.095 13.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain TPR_1 PF00515.23 KEG14058.1 - 0.076 12.6 2.3 0.1 12.2 0.2 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat AAA_28 PF13521.1 KEG14058.1 - 0.082 12.8 0.1 0.38 10.6 0.1 2.0 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 KEG14058.1 - 0.087 12.0 0.0 0.21 10.8 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein TPR_2 PF07719.12 KEG14058.1 - 1.6 8.8 5.2 0.6 10.1 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat PFK PF00365.15 KEG14059.1 - 2.2e-38 131.8 1.2 3.4e-38 131.2 0.9 1.2 1 0 0 1 1 1 1 Phosphofructokinase NAD_kinase PF01513.16 KEG14059.1 - 0.00048 18.9 0.0 0.00086 18.1 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase DUF3813 PF12758.2 KEG14059.1 - 0.18 11.9 0.1 0.18 11.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) Spore_coat_CotO PF14153.1 KEG14060.1 - 0.00048 19.6 11.5 0.00051 19.5 8.0 1.2 1 0 0 1 1 1 1 Spore coat protein CotO TFIIF_alpha PF05793.7 KEG14060.1 - 0.0021 16.5 22.6 0.0025 16.2 15.7 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ycf1 PF05758.7 KEG14060.1 - 0.0049 14.6 5.1 0.004 14.9 3.6 1.0 1 0 0 1 1 1 1 Ycf1 DUF605 PF04652.11 KEG14060.1 - 0.28 10.5 9.0 0.34 10.2 6.2 1.1 1 0 0 1 1 1 0 Vta1 like CDC45 PF02724.9 KEG14060.1 - 0.31 9.0 16.8 0.35 8.8 11.7 1.1 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.10 KEG14060.1 - 0.53 8.8 11.3 0.57 8.7 7.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SDA1 PF05285.7 KEG14060.1 - 0.65 9.2 28.3 0.84 8.8 19.6 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 KEG14060.1 - 0.7 7.7 36.1 0.9 7.3 25.0 1.1 1 0 0 1 1 1 0 Nop14-like family Lin-8 PF03353.10 KEG14060.1 - 0.79 8.9 15.0 1 8.5 10.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF1510 PF07423.6 KEG14060.1 - 1.1 8.5 24.5 1.9 7.7 17.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF4045 PF13254.1 KEG14060.1 - 1.5 8.0 11.8 2.2 7.4 8.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Menin PF05053.8 KEG14060.1 - 7.8 4.5 12.6 9.7 4.2 8.7 1.1 1 0 0 1 1 1 0 Menin zf-MIZ PF02891.15 KEG14061.1 - 9.8e-06 24.9 0.4 8.6e-05 21.9 0.0 2.3 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 KEG14061.1 - 0.014 14.9 0.0 0.042 13.3 0.0 1.8 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Nol1_Nop2_Fmu PF01189.12 KEG14063.1 - 1.4e-30 106.6 0.1 8.7e-29 100.7 0.0 2.3 2 0 0 2 2 2 1 NOL1/NOP2/sun family FtsJ PF01728.14 KEG14063.1 - 3.3e-06 27.2 0.1 6.3e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 KEG14063.1 - 2.3e-05 24.4 0.0 6.3e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEG14063.1 - 0.055 14.0 0.0 0.16 12.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KEG14063.1 - 0.15 11.6 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TPR_19 PF14559.1 KEG14065.1 - 6.7e-19 67.9 23.2 4.3e-08 33.3 1.2 7.3 6 1 2 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.1 KEG14065.1 - 4.2e-16 58.3 11.4 2.1e-05 24.0 0.3 6.9 7 1 1 8 8 8 4 TPR repeat TPR_12 PF13424.1 KEG14065.1 - 1.7e-11 43.9 23.5 0.0011 18.8 0.0 7.5 5 2 1 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 KEG14065.1 - 5.3e-11 42.1 24.0 0.013 16.0 0.1 9.0 5 2 3 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.12 KEG14065.1 - 2.2e-09 36.4 15.7 0.0014 18.3 0.1 8.1 9 0 0 9 9 9 2 Tetratricopeptide repeat Apc3 PF12895.2 KEG14065.1 - 4.4e-09 36.3 8.5 0.37 10.9 0.1 7.3 4 3 5 9 9 9 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 KEG14065.1 - 1e-08 34.4 5.4 0.022 14.3 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEG14065.1 - 7.1e-05 23.3 48.0 0.036 14.7 0.3 9.6 6 3 4 11 11 11 5 Tetratricopeptide repeat TPR_6 PF13174.1 KEG14065.1 - 0.00057 20.1 9.7 18 6.0 0.0 8.8 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_17 PF13431.1 KEG14065.1 - 0.011 15.9 10.9 0.034 14.3 0.2 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF4586 PF15239.1 KEG14066.1 - 3e-74 250.2 9.9 3.6e-74 250.0 6.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) Pkinase PF00069.20 KEG14067.1 - 3.2e-68 229.7 0.0 5.6e-68 228.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG14067.1 - 2e-48 164.7 0.0 3.2e-48 164.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG14067.1 - 4.1e-08 32.5 0.1 7.5e-08 31.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KEG14067.1 - 0.011 15.5 0.0 1.9 8.1 0.0 2.3 1 1 0 2 2 2 0 Phosphotransferase enzyme family Glyco_transf_8C PF08437.5 KEG14068.1 - 1.2 9.2 3.8 0.95 9.5 1.1 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 8 C-terminal DUF605 PF04652.11 KEG14069.1 - 8.3 5.6 11.9 9.6 5.4 8.3 1.1 1 0 0 1 1 1 0 Vta1 like DCX PF03607.12 KEG14070.1 - 2e-11 43.2 0.1 3.1e-05 23.4 0.1 2.4 2 0 0 2 2 2 2 Doublecortin Mucin PF01456.12 KEG14070.1 - 1.6 8.4 58.7 1 9.1 11.0 3.5 3 0 0 3 3 3 0 Mucin-like glycoprotein Hamartin PF04388.7 KEG14070.1 - 4 5.9 12.1 0.11 11.0 0.7 2.4 2 0 0 2 2 2 0 Hamartin protein PAP_central PF04928.12 KEG14072.1 - 9.7e-34 116.3 0.1 1.3e-33 115.9 0.1 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 KEG14072.1 - 0.00041 19.9 0.0 0.00084 18.8 0.0 1.5 1 1 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain ADIP PF11559.3 KEG14073.1 - 0.29 11.0 16.8 0.2 11.5 1.5 4.2 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding DUF1192 PF06698.6 KEG14073.1 - 0.39 10.5 5.9 0.31 10.8 1.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DivIC PF04977.10 KEG14073.1 - 4 6.9 18.3 0.6 9.6 1.2 4.4 4 0 0 4 4 4 0 Septum formation initiator DUF3317 PF11779.3 KEG14074.1 - 0.29 10.5 2.1 0.48 9.9 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3317) SAM_2 PF07647.12 KEG14075.1 - 2.4e-06 27.3 0.1 6.5e-06 25.9 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KEG14075.1 - 4.4e-05 23.5 0.4 0.00021 21.3 0.1 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Trp_dioxygenase PF03301.8 KEG14075.1 - 0.025 13.6 0.4 0.066 12.3 0.2 1.6 1 0 0 1 1 1 0 Tryptophan 2,3-dioxygenase Med3 PF11593.3 KEG14076.1 - 0.033 13.4 0.6 0.039 13.1 0.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CAF-1_p150 PF11600.3 KEG14076.1 - 1.5 8.1 5.6 2.3 7.5 3.9 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ras PF00071.17 KEG14077.1 - 8.6e-38 129.2 0.0 1.1e-37 128.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEG14077.1 - 6.6e-19 68.5 0.0 1.3e-18 67.6 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEG14077.1 - 1.6e-15 56.7 0.0 2.4e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KEG14077.1 - 3.3e-05 23.1 0.0 4.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KEG14077.1 - 0.00069 19.5 0.0 0.0019 18.1 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase G-alpha PF00503.15 KEG14077.1 - 0.00074 18.3 0.1 0.029 13.0 0.0 2.1 1 1 1 2 2 2 1 G-protein alpha subunit PduV-EutP PF10662.4 KEG14077.1 - 0.0074 15.7 0.1 0.028 13.9 0.0 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 KEG14077.1 - 0.12 11.5 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Aldedh PF00171.17 KEG14078.1 - 3.2e-88 296.0 0.0 3.7e-88 295.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pox_TAA1 PF03295.9 KEG14078.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Poxvirus trans-activator protein A1 C-terminal Noelin-1 PF12308.3 KEG14079.1 - 0.095 12.5 0.1 0.26 11.1 0.1 1.7 1 0 0 1 1 1 0 Neurogenesis glycoprotein CENP-F_leu_zip PF10473.4 KEG14080.1 - 0.018 14.9 16.5 0.12 12.2 2.0 3.6 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Occludin_ELL PF07303.8 KEG14080.1 - 0.23 12.2 6.2 1.6 9.4 0.2 3.2 2 1 1 3 3 3 0 Occludin homology domain IFP_35_N PF07334.8 KEG14080.1 - 2.9 7.9 13.2 0.92 9.5 0.2 3.6 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Herpes_UL6 PF01763.11 KEG14080.1 - 5.8 4.9 10.4 0.092 10.9 1.6 1.9 2 1 0 2 2 2 0 Herpesvirus UL6 like PepSY_TM_3 PF13706.1 KEG14081.1 - 0.037 13.4 1.3 0.07 12.5 0.9 1.5 1 0 0 1 1 1 0 PepSY-associated TM helix Kelch_6 PF13964.1 KEG14082.1 - 3.9e-17 61.5 4.6 7.8e-05 22.6 0.1 6.9 7 1 0 7 7 7 4 Kelch motif Kelch_3 PF13415.1 KEG14082.1 - 7.2e-13 48.3 12.1 0.00021 21.3 0.2 6.9 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.1 KEG14082.1 - 4.2e-11 42.4 16.1 0.035 13.8 0.5 6.8 5 3 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 KEG14082.1 - 5.8e-11 42.0 11.8 0.11 12.4 0.1 6.1 5 1 0 5 5 5 5 Kelch motif Kelch_1 PF01344.20 KEG14082.1 - 8.6e-10 38.0 9.2 0.0034 16.9 0.1 6.0 5 3 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 KEG14082.1 - 4.4e-06 26.2 9.0 0.00041 19.9 0.3 5.0 6 0 0 6 6 6 1 Kelch motif Pup PF05639.6 KEG14082.1 - 0.089 13.3 0.1 0.089 13.3 0.1 2.2 3 0 0 3 3 3 0 Pup-like protein CLASP_N PF12348.3 KEG14083.1 - 1.1e-12 47.7 8.1 8.6e-09 35.0 0.4 6.1 5 2 0 5 5 5 2 CLASP N terminal HEAT PF02985.17 KEG14083.1 - 1e-08 34.4 3.2 5.4 7.3 0.0 9.3 11 0 0 11 11 11 3 HEAT repeat NUC173 PF08161.7 KEG14083.1 - 0.00038 19.8 0.5 0.14 11.5 0.0 3.3 3 1 1 4 4 4 2 NUC173 domain HEAT_EZ PF13513.1 KEG14083.1 - 0.55 10.7 8.6 29 5.2 0.0 7.2 8 1 1 9 9 9 0 HEAT-like repeat IFT46_B_C PF12317.3 KEG14085.1 - 7.2e-91 303.3 0.5 1.1e-90 302.7 0.4 1.3 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal Pkinase PF00069.20 KEG14086.1 - 2e-38 132.0 0.0 3e-38 131.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG14086.1 - 3.2e-14 52.6 0.0 5.4e-14 51.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEG14086.1 - 7.3e-05 22.6 0.1 0.00071 19.3 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KEG14086.1 - 0.0089 15.0 0.0 0.035 13.0 0.0 1.7 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 KEG14086.1 - 0.017 14.5 0.0 0.56 9.5 0.0 2.1 2 0 0 2 2 2 0 RIO1 family ART PF01129.13 KEG14086.1 - 0.087 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase DnaJ PF00226.26 KEG14087.1 - 0.06 13.0 0.7 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 DnaJ domain TGT PF01702.13 KEG14088.1 - 3.1e-90 301.6 0.0 3.8e-90 301.3 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase ubiquitin PF00240.18 KEG14089.1 - 0.0011 18.3 0.0 0.0016 17.7 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin family PapD-like PF14874.1 KEG14090.1 - 1.2e-18 66.8 21.6 0.011 15.7 0.0 14.2 17 0 0 17 17 17 5 Flagellar-associated PapD-like MYCBPAP PF14646.1 KEG14090.1 - 9.8e-17 60.7 1.5 0.0065 15.2 0.0 8.6 10 0 0 10 10 10 4 MYCBP-associated protein family Motile_Sperm PF00635.21 KEG14090.1 - 4.9e-10 39.0 16.4 0.16 11.6 0.0 13.5 18 0 0 18 18 18 1 MSP (Major sperm protein) domain ADK PF00406.17 KEG14090.1 - 0.0035 17.2 0.0 0.012 15.5 0.0 1.9 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.1 KEG14090.1 - 0.012 16.4 0.0 0.033 15.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain MATH PF00917.21 KEG14090.1 - 0.35 11.1 0.0 0.85 9.8 0.0 1.6 1 0 0 1 1 1 0 MATH domain adh_short PF00106.20 KEG14091.1 - 5.6e-07 29.6 0.0 0.0001 22.2 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 KEG14091.1 - 0.00047 19.9 0.0 0.12 12.1 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEG14091.1 - 0.094 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 KR domain Arm PF00514.18 KEG14092.1 - 0.0018 18.0 0.0 0.0081 15.9 0.0 2.2 1 0 0 1 1 1 1 Armadillo/beta-catenin-like repeat MAS20 PF02064.10 KEG14092.1 - 0.015 15.1 2.7 0.045 13.6 1.5 2.1 2 0 0 2 2 2 0 MAS20 protein import receptor DUF3829 PF12889.2 KEG14092.1 - 1.1 8.4 6.1 1.2 8.2 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) EF-hand_5 PF13202.1 KEG14094.1 - 8.4e-08 31.2 2.2 0.0031 16.7 0.2 3.3 3 1 0 3 3 3 2 EF hand EF-hand_1 PF00036.27 KEG14094.1 - 4.9e-07 28.5 0.6 0.079 12.3 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 KEG14094.1 - 5.9e-05 22.6 2.5 0.12 12.3 0.0 3.3 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 KEG14094.1 - 0.00034 20.6 1.0 0.0079 16.3 0.3 2.6 1 1 1 2 2 2 2 EF-hand domain pair Dockerin_1 PF00404.13 KEG14094.1 - 0.008 15.8 7.3 0.16 11.7 0.0 3.5 4 0 0 4 4 4 2 Dockerin type I repeat VCBS PF13517.1 KEG14094.1 - 0.063 13.6 0.0 15 6.0 0.0 2.6 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 KEG14094.1 - 0.096 12.4 2.2 1.9 8.2 0.0 2.5 2 0 0 2 2 2 0 FG-GAP repeat Exo_endo_phos PF03372.18 KEG14095.1 - 7.8e-13 48.9 0.1 1.4e-12 48.0 0.1 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Myf5 PF12232.3 KEG14095.1 - 2.2 8.9 5.4 12 6.5 0.2 3.2 3 0 0 3 3 3 0 Myogenic determination factor 5 TBPIP PF07106.8 KEG14096.1 - 0.0016 18.0 26.0 0.063 12.8 4.5 3.2 1 1 2 3 3 3 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mnd1 PF03962.10 KEG14096.1 - 0.0073 15.9 29.7 0.06 13.0 4.5 3.1 1 1 2 3 3 3 2 Mnd1 family DivIC PF04977.10 KEG14096.1 - 0.012 15.1 3.5 0.012 15.1 2.4 5.0 2 1 3 5 5 5 0 Septum formation initiator DUF2848 PF11010.3 KEG14096.1 - 0.016 14.7 1.7 0.96 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2848) RILP PF11461.3 KEG14096.1 - 0.065 13.4 0.2 0.065 13.4 0.2 4.1 4 1 0 4 4 4 0 Rab interacting lysosomal protein PPDK_N PF01326.14 KEG14096.1 - 0.085 11.8 8.0 0.029 13.4 3.8 1.6 1 1 0 1 1 1 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain Syntaxin_2 PF14523.1 KEG14096.1 - 0.087 12.8 16.0 0.9 9.6 0.8 3.8 2 2 2 4 4 4 0 Syntaxin-like protein Surfac_D-trimer PF09006.6 KEG14096.1 - 0.96 9.2 10.9 3.7 7.3 0.1 4.2 4 0 0 4 4 4 0 Lung surfactant protein D coiled-coil trimerisation KaiC PF06745.8 KEG14096.1 - 0.99 8.4 6.6 1.6 7.7 4.6 1.3 1 0 0 1 1 1 0 KaiC NPV_P10 PF05531.7 KEG14096.1 - 1.2 9.4 11.7 3 8.1 0.4 3.7 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein HAMP PF00672.20 KEG14096.1 - 1.4 9.1 6.2 25 5.1 0.1 3.4 3 1 0 3 3 3 0 HAMP domain IFT57 PF10498.4 KEG14096.1 - 2.3 6.8 17.7 1.6 7.3 1.0 2.0 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF972 PF06156.8 KEG14096.1 - 3.3 8.0 25.4 8.8 6.7 1.5 4.5 1 1 3 4 4 4 0 Protein of unknown function (DUF972) CorA PF01544.13 KEG14096.1 - 3.8 6.4 10.5 5.3 5.9 6.5 1.9 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein CDC37_N PF03234.9 KEG14096.1 - 5.8 7.1 20.9 0.49 10.6 4.7 2.6 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding Ribonuc_red_lgC PF02867.10 KEG14097.1 - 9.6e-213 707.6 0.0 1.2e-212 707.2 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 KEG14097.1 - 1.8e-22 78.8 0.0 4.9e-22 77.5 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 KEG14097.1 - 3.1e-11 43.5 0.0 2.4e-10 40.7 0.0 2.4 2 0 0 2 2 2 1 ATP cone domain zf-ribbon_3 PF13248.1 KEG14100.1 - 0.067 12.4 1.1 0.12 11.5 0.7 1.5 1 0 0 1 1 1 0 zinc-ribbon domain MCM PF00493.18 KEG14101.1 - 1.6e-131 438.0 0.0 3.6e-131 436.8 0.0 1.6 1 1 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KEG14101.1 - 9.9e-12 45.4 0.2 9.9e-12 45.4 0.2 2.6 3 0 0 3 3 3 1 MCM N-terminal domain MCM2_N PF12619.3 KEG14101.1 - 1.7e-10 41.0 26.0 1.7e-10 41.0 18.0 2.8 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 Mg_chelatase PF01078.16 KEG14101.1 - 1.8e-06 27.2 0.0 9.8e-05 21.5 0.0 2.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KEG14101.1 - 1.6e-05 24.6 0.0 3.4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KEG14101.1 - 0.00079 19.0 0.0 0.011 15.2 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KEG14101.1 - 0.046 13.1 0.1 0.13 11.7 0.1 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain DUF1738 PF08401.6 KEG14102.1 - 2.9e-06 27.0 0.0 0.0075 16.0 0.0 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF1738) DUF3421 PF11901.3 KEG14102.1 - 0.027 14.2 0.0 0.062 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3421) HTH_29 PF13551.1 KEG14103.1 - 0.0043 17.1 0.7 0.0074 16.4 0.5 1.3 1 0 0 1 1 1 1 Winged helix-turn helix CSD PF00313.17 KEG14105.1 - 2.9e-17 62.2 0.9 3.8e-17 61.8 0.6 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain DUF3273 PF11677.3 KEG14106.1 - 0.042 13.1 0.1 0.056 12.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3273) RNA_pol_Rpb8 PF03870.10 KEG14108.1 - 2.1e-26 92.7 0.0 2.3e-26 92.6 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 EF-hand_9 PF14658.1 KEG14109.1 - 2.3e-16 59.4 0.1 6.9e-16 57.9 0.0 1.8 2 1 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 KEG14109.1 - 1.2e-09 36.7 0.1 0.013 14.7 0.0 4.0 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 KEG14109.1 - 1.9e-08 34.2 0.0 0.0037 17.3 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KEG14109.1 - 4.6e-08 32.2 0.0 0.0043 16.8 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 KEG14109.1 - 0.00018 21.0 2.5 1.8 8.2 0.0 3.7 2 2 1 3 3 3 3 EF-hand domain pair Nsp1 PF11501.3 KEG14109.1 - 0.023 14.5 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 Non structural protein Nsp1 EF-hand_like PF09279.6 KEG14109.1 - 0.099 12.6 0.4 10 6.2 0.0 2.5 1 1 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like DSPc PF00782.15 KEG14110.1 - 8.2e-19 67.5 0.0 1.8e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PI3K_p85B PF02192.11 KEG14110.1 - 0.02 14.2 0.1 0.28 10.6 0.0 2.3 2 0 0 2 2 2 0 PI3-kinase family, p85-binding domain Y_phosphatase PF00102.22 KEG14110.1 - 0.062 12.6 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PAP_assoc PF03828.14 KEG14111.1 - 2e-13 50.0 0.0 4.4e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase Peptidase_M32 PF02074.10 KEG14113.1 - 5.7e-25 87.9 0.4 6.6e-25 87.7 0.3 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase Soyouz_module PF14313.1 KEG14113.1 - 0.062 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 N-terminal region of Paramyxovirinae phosphoprotein (P) NUC173 PF08161.7 KEG14114.1 - 1e-12 47.8 0.1 4.9e-12 45.6 0.0 2.2 2 0 0 2 2 2 1 NUC173 domain DHH PF01368.15 KEG14114.1 - 0.047 13.3 0.1 0.88 9.2 0.0 2.4 2 0 0 2 2 2 0 DHH family YidC_periplas PF14849.1 KEG14114.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 YidC periplasmic domain UDPGP PF01704.13 KEG14115.1 - 1.2e-27 96.5 0.0 1.5e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase MTS PF05175.9 KEG14117.1 - 0.1 11.9 0.0 5.4 6.3 0.0 2.7 3 0 0 3 3 3 0 Methyltransferase small domain Radial_spoke PF04712.7 KEG14119.1 - 0.001 17.8 0.0 0.006 15.3 0.0 2.0 3 0 0 3 3 3 1 Radial spokehead-like protein Rad51 PF08423.6 KEG14121.1 - 2.4e-27 95.4 0.4 1.5e-18 66.6 0.0 4.3 3 1 0 4 4 4 4 Rad51 AAA_25 PF13481.1 KEG14121.1 - 2.9e-13 49.6 0.1 8e-12 44.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 KEG14121.1 - 1e-05 24.8 0.1 0.00016 20.8 0.0 2.4 2 0 0 2 2 2 1 KaiC RecA PF00154.16 KEG14121.1 - 1.4e-05 24.2 0.1 8.5e-05 21.7 0.1 2.0 2 0 0 2 2 2 1 recA bacterial DNA recombination protein Eno-Rase_NADH_b PF12242.3 KEG14121.1 - 0.002 17.8 0.0 0.0055 16.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AAA_33 PF13671.1 KEG14121.1 - 0.0056 16.5 0.1 0.079 12.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KEG14121.1 - 0.01 15.5 0.2 0.054 13.2 0.1 2.3 2 0 0 2 2 2 0 Part of AAA domain AAA_22 PF13401.1 KEG14121.1 - 0.012 15.7 0.0 0.19 11.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA PF00004.24 KEG14121.1 - 0.016 15.4 0.0 0.063 13.4 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 KEG14121.1 - 0.042 13.2 0.0 0.084 12.2 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain NACHT PF05729.7 KEG14121.1 - 0.13 11.9 0.5 0.84 9.2 0.0 2.4 3 0 0 3 3 3 0 NACHT domain DUF3293 PF11697.3 KEG14122.1 - 0.11 12.6 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3293) DUF1640 PF07798.6 KEG14122.1 - 0.13 12.3 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) EF-hand_8 PF13833.1 KEG14123.1 - 0.0002 20.8 0.0 0.065 12.8 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.1 KEG14123.1 - 0.0051 16.9 0.0 3.8 7.7 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KEG14123.1 - 0.0086 15.3 0.0 1.1 8.7 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 KEG14123.1 - 0.086 12.7 0.1 0.37 10.8 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain Ribosomal_60s PF00428.14 KEG14123.1 - 0.23 11.8 14.0 0.24 11.8 6.6 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein BRCT PF00533.21 KEG14126.1 - 0.061 13.4 0.3 0.13 12.4 0.0 1.7 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain DUF3420 PF11900.3 KEG14127.1 - 0.046 13.8 3.7 15 5.7 0.6 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3420) DUF1816 PF08846.5 KEG14127.1 - 0.11 12.2 0.3 0.31 10.7 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1816) zf-MYND PF01753.13 KEG14129.1 - 2.3e-11 43.3 35.3 1.2e-05 25.0 8.6 2.6 2 0 0 2 2 2 2 MYND finger Diphthamide_syn PF01866.12 KEG14130.1 - 1.6e-31 109.6 0.3 1.8e-16 60.3 0.0 3.4 4 0 0 4 4 4 2 Putative diphthamide synthesis protein MMR_HSR1 PF01926.18 KEG14131.1 - 1.2e-18 67.1 0.2 1.7e-13 50.5 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 KEG14131.1 - 1.2e-11 44.1 0.5 1.9e-08 33.7 0.3 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B Dynamin_N PF00350.18 KEG14131.1 - 2.4e-05 24.2 2.9 0.015 15.0 0.1 3.2 2 2 1 3 3 3 1 Dynamin family GTP_EFTU PF00009.22 KEG14131.1 - 0.00037 19.9 0.3 0.0085 15.5 0.0 2.5 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KEG14131.1 - 0.0073 15.5 0.0 0.016 14.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ArgK PF03308.11 KEG14131.1 - 0.026 13.2 0.0 0.046 12.4 0.0 1.3 1 0 0 1 1 1 0 ArgK protein Miro PF08477.8 KEG14131.1 - 0.037 14.5 0.2 2.1 8.8 0.0 2.3 2 0 0 2 2 2 0 Miro-like protein AAA_17 PF13207.1 KEG14131.1 - 0.05 14.4 0.8 0.27 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KEG14131.1 - 0.06 13.4 0.1 11 6.1 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KEG14131.1 - 0.13 12.5 0.1 0.5 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain HSP90 PF00183.13 KEG14132.1 - 1.7e-75 254.4 2.1 7.6e-75 252.3 0.3 2.0 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.1 KEG14132.1 - 1.4e-13 50.6 0.1 3.3e-13 49.4 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KEG14132.1 - 9e-06 25.3 0.0 2.6e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_S19e PF01090.14 KEG14134.1 - 5.3e-46 155.5 0.0 6.3e-46 155.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19e Mrr_N PF14338.1 KEG14134.1 - 0.0085 16.1 0.1 0.037 14.1 0.0 1.9 2 0 0 2 2 2 1 Mrr N-terminal domain Peptidase_M14 PF00246.19 KEG14136.1 - 7.8e-27 94.5 0.1 1.8e-26 93.3 0.0 1.5 2 0 0 2 2 2 1 Zinc carboxypeptidase AstE_AspA PF04952.9 KEG14136.1 - 0.0011 17.9 0.0 0.0019 17.1 0.0 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family cNMP_binding PF00027.24 KEG14137.1 - 1.1e-26 92.4 0.4 2.2e-13 49.8 0.1 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Urm1 PF09138.6 KEG14138.1 - 1.7e-28 98.5 0.0 1.9e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 KEG14138.1 - 1.2e-06 28.7 0.0 1.5e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 ThiS family GTP_EFTU PF00009.22 KEG14139.1 - 1.5e-30 106.0 0.0 2.4e-30 105.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KEG14139.1 - 7.4e-08 32.3 0.0 4.3e-07 29.9 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 KEG14139.1 - 1.5e-07 31.4 0.4 3.9e-07 30.0 0.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 KEG14139.1 - 0.00028 20.4 0.1 0.00072 19.1 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 PduV-EutP PF10662.4 KEG14139.1 - 0.00039 19.9 0.3 0.22 11.0 0.1 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 KEG14139.1 - 0.0022 17.2 0.0 0.013 14.7 0.0 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 KEG14139.1 - 0.029 13.6 0.0 0.068 12.3 0.0 1.5 2 0 0 2 2 2 0 ADP-ribosylation factor family cobW PF02492.14 KEG14139.1 - 0.06 12.7 0.9 0.22 10.9 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Hexapep PF00132.19 KEG14140.1 - 3.9e-12 45.1 11.6 9.2e-08 31.2 1.1 3.3 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KEG14140.1 - 0.00058 19.3 8.3 0.01 15.3 1.5 2.7 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Ribosomal_L33 PF00471.15 KEG14141.1 - 0.12 12.6 0.2 0.22 11.8 0.1 1.6 1 1 0 1 1 1 0 Ribosomal protein L33 Ribosomal_L3 PF00297.17 KEG14143.1 - 3.1e-101 338.1 8.2 3.8e-101 337.8 5.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 Patatin PF01734.17 KEG14144.1 - 3e-07 30.5 0.7 2.3e-06 27.6 0.5 2.1 1 1 0 1 1 1 1 Patatin-like phospholipase PPR PF01535.15 KEG14144.1 - 0.18 11.8 0.8 5.2 7.2 0.1 2.8 2 0 0 2 2 2 0 PPR repeat COX6C PF02937.10 KEG14145.1 - 0.056 13.3 0.1 0.099 12.5 0.0 1.4 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIc SBDS_C PF09377.5 KEG14145.1 - 0.082 12.6 0.0 0.09 12.4 0.0 1.0 1 0 0 1 1 1 0 SBDS protein C-terminal domain Thioredoxin PF00085.15 KEG14146.1 - 0.00099 18.7 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KEG14146.1 - 0.13 12.4 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain PTEN_C2 PF10409.4 KEG14147.1 - 1.6e-13 50.5 0.0 2.7e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein PTPlike_phytase PF14566.1 KEG14147.1 - 1.2e-05 25.4 0.0 2.1e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 KEG14147.1 - 1.5e-05 25.3 0.0 2.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 KEG14147.1 - 0.0002 20.7 0.0 0.00032 20.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KEG14147.1 - 0.00086 18.9 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.8 KEG14147.1 - 0.0024 17.2 0.0 0.0042 16.4 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Cys_rich_FGFR PF00839.12 KEG14147.1 - 0.098 12.5 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Cysteine rich repeat IpgD PF05925.7 KEG14147.1 - 0.2 9.8 0.0 0.31 9.2 0.0 1.2 1 0 0 1 1 1 0 Enterobacterial virulence protein IpgD PDZ_2 PF13180.1 KEG14149.1 - 1.7e-07 31.0 0.1 7.9e-07 28.8 0.0 2.1 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.19 KEG14149.1 - 3.1e-07 30.4 0.0 9.2e-07 28.9 0.0 1.8 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Thioredoxin_2 PF13098.1 KEG14149.1 - 0.09 12.9 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain PspA_IM30 PF04012.7 KEG14149.1 - 0.71 9.1 11.4 0.15 11.3 3.9 2.5 2 1 1 3 3 3 0 PspA/IM30 family EF-hand_7 PF13499.1 KEG14150.1 - 3.2e-16 59.2 1.0 0.00011 22.2 0.0 5.0 3 2 2 5 5 5 5 EF-hand domain pair EF-hand_1 PF00036.27 KEG14150.1 - 1e-11 43.2 1.1 0.0059 15.8 0.0 6.7 6 0 0 6 6 6 3 EF hand EF-hand_8 PF13833.1 KEG14150.1 - 4.3e-11 42.2 0.4 5.9e-07 28.9 0.0 4.5 5 0 0 5 5 5 2 EF-hand domain pair EF-hand_6 PF13405.1 KEG14150.1 - 2.4e-09 36.2 2.5 0.0056 16.4 0.0 5.9 7 0 0 7 7 7 2 EF-hand domain EF-hand_5 PF13202.1 KEG14150.1 - 3.2e-06 26.2 5.4 0.085 12.2 0.0 5.6 7 0 0 7 7 7 2 EF hand HyaE PF07449.6 KEG14150.1 - 0.042 13.7 0.0 0.099 12.5 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DUF2962 PF11176.3 KEG14151.1 - 0.0092 15.5 2.9 0.0092 15.5 2.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF2962) Atg14 PF10186.4 KEG14151.1 - 0.018 14.0 6.3 0.022 13.6 4.4 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 AAA_assoc_C PF09821.4 KEG14151.1 - 0.92 9.7 7.3 0.16 12.2 0.9 2.1 1 1 2 3 3 3 0 C-terminal AAA-associated domain DUF4337 PF14235.1 KEG14151.1 - 3.1 7.6 7.1 5.1 6.9 5.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) APG6 PF04111.7 KEG14151.1 - 7.5 5.4 14.4 8.9 5.2 10.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 HSDR_N_2 PF13588.1 KEG14152.1 - 0.022 14.5 0.1 0.054 13.3 0.0 1.7 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) HSDR_N PF04313.9 KEG14152.1 - 0.065 12.9 0.7 0.13 11.9 0.2 1.8 2 1 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) NDK PF00334.14 KEG14153.1 - 1.5e-21 76.6 0.0 4.2e-21 75.1 0.0 1.8 2 0 0 2 2 2 1 Nucleoside diphosphate kinase Rhodanese PF00581.15 KEG14154.1 - 2.6e-13 50.3 0.0 4.4e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Pkinase PF00069.20 KEG14155.1 - 2.5e-22 79.2 0.0 4.5e-22 78.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 KEG14155.1 - 0.00097 18.9 0.0 0.0058 16.3 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KEG14155.1 - 0.034 13.2 0.0 0.054 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RMP PF14996.1 KEG14156.1 - 1.4e-10 41.2 2.0 1.9e-09 37.5 0.2 2.9 2 1 0 2 2 2 1 Retinal Maintenance Beta_helix PF13229.1 KEG14157.1 - 1.1e-05 25.2 0.0 5.7e-05 22.9 0.0 2.1 2 1 0 2 2 2 1 Right handed beta helix region NosD PF05048.8 KEG14157.1 - 1.9e-05 23.9 0.0 2.9e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Adeno_E1B_55K PF01696.12 KEG14157.1 - 0.06 11.8 8.8 0.079 11.4 2.6 2.1 2 0 0 2 2 2 0 Adenovirus EB1 55K protein / large t-antigen VGLL4 PF15245.1 KEG14157.1 - 0.39 10.5 3.1 0.64 9.8 2.1 1.4 1 1 0 1 1 1 0 Transcription cofactor vestigial-like protein 4 Cyt-b5 PF00173.23 KEG14158.1 - 5.5e-07 29.2 0.0 7.7e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ResIII PF04851.10 KEG14159.1 - 3.3e-13 49.8 0.0 5.6e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T5orf172 PF10544.4 KEG14159.1 - 5.3e-09 36.3 0.0 1.4e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 T5orf172 domain DEAD PF00270.24 KEG14159.1 - 3.6e-06 26.5 0.0 6.1e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEG14159.1 - 5.2e-05 23.0 0.0 0.00013 21.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain MUG113 PF13455.1 KEG14159.1 - 0.00015 22.1 0.0 0.0006 20.2 0.0 2.1 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 DUF3505 PF12013.3 KEG14159.1 - 0.031 14.5 0.7 0.11 12.7 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) TPR_19 PF14559.1 KEG14160.1 - 0.017 15.4 1.2 0.031 14.6 0.0 2.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEG14160.1 - 0.11 13.2 1.1 0.63 10.8 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 KEG14160.1 - 0.42 11.3 3.0 0.9 10.2 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-CCCH PF00642.19 KEG14161.1 - 4e-05 23.1 3.2 4e-05 23.1 2.2 2.6 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KEG14161.1 - 0.033 14.1 9.9 1.7 8.7 3.8 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type GCS PF03074.11 KEG14165.1 - 3.1e-168 559.5 0.8 5.5e-168 558.7 0.6 1.4 1 0 0 1 1 1 1 Glutamate-cysteine ligase DnaJ PF00226.26 KEG14166.1 - 5.4e-12 45.2 0.0 1.5e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain TPR_11 PF13414.1 KEG14166.1 - 1.6e-07 30.8 12.3 1.8e-07 30.7 0.3 4.8 3 2 1 4 4 4 1 TPR repeat TPR_1 PF00515.23 KEG14166.1 - 0.00027 20.4 0.9 2.6 7.8 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEG14166.1 - 0.0025 17.5 7.4 3.2 7.8 0.2 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 KEG14166.1 - 0.013 15.6 1.1 0.013 15.6 0.8 4.0 3 3 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 KEG14166.1 - 0.038 13.7 1.7 6.4 6.8 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 KEG14166.1 - 0.24 12.1 9.1 2.1 9.1 0.0 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEG14166.1 - 0.34 11.6 6.8 7.7 7.4 0.1 5.3 5 1 1 6 6 6 0 Tetratricopeptide repeat DP PF08781.5 KEG14168.1 - 0.18 11.4 1.8 0.44 10.2 1.2 1.6 1 0 0 1 1 1 0 Transcription factor DP MatE PF01554.13 KEG14169.1 - 4e-40 137.0 32.2 2.5e-30 105.2 7.4 2.7 3 0 0 3 3 3 2 MatE DUF2678 PF10856.3 KEG14169.1 - 0.57 9.9 4.1 0.72 9.5 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2678) Got1 PF04178.7 KEG14171.1 - 1e-16 61.0 15.2 1.2e-16 60.9 10.6 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family COPI_assoc PF08507.5 KEG14171.1 - 2.8 7.6 11.3 2 8.1 3.1 2.2 2 0 0 2 2 2 0 COPI associated protein DUF872 PF05915.7 KEG14171.1 - 9.8 6.0 9.1 4.4 7.1 3.5 2.3 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Noc2 PF03715.8 KEG14172.1 - 9.2e-100 333.3 0.1 9.2e-100 333.3 0.1 1.7 2 0 0 2 2 2 1 Noc2p family DUF4441 PF14536.1 KEG14172.1 - 0.093 12.7 1.6 0.21 11.5 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4441) Potyvirid-P3 PF13608.1 KEG14172.1 - 0.34 9.9 4.6 0.98 8.4 3.2 1.8 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein Kinesin PF00225.18 KEG14173.1 - 1.4e-63 214.6 0.1 2.8e-63 213.6 0.1 1.5 1 0 0 1 1 1 1 Kinesin motor domain Longin PF13774.1 KEG14174.1 - 2.2e-22 78.4 0.1 3.3e-22 77.8 0.1 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain SRP-alpha_N PF04086.8 KEG14174.1 - 0.14 11.5 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PsbX PF06596.6 KEG14174.1 - 0.36 10.5 3.3 0.67 9.6 2.3 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) zf-C3HC4_3 PF13920.1 KEG14175.1 - 2.4e-12 46.3 17.2 4.1e-12 45.5 11.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEG14175.1 - 0.0024 17.8 14.9 0.0027 17.7 9.5 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SlyX PF04102.7 KEG14175.1 - 0.093 13.1 0.1 0.15 12.4 0.1 1.3 1 0 0 1 1 1 0 SlyX Prok-RING_4 PF14447.1 KEG14175.1 - 0.47 10.0 11.4 0.78 9.3 7.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 AAA_13 PF13166.1 KEG14177.1 - 0.027 12.9 3.0 0.051 12.0 2.1 1.4 1 0 0 1 1 1 0 AAA domain Cauli_AT PF03233.8 KEG14177.1 - 0.15 11.7 0.1 14 5.3 0.0 2.6 2 1 0 2 2 2 0 Aphid transmission protein DUF4200 PF13863.1 KEG14177.1 - 5 7.1 12.8 3.5 7.5 2.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Mod_r PF07200.8 KEG14177.1 - 8.6 6.2 9.8 3.9 7.3 0.9 2.7 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein UAA PF08449.6 KEG14178.1 - 1.2e-45 155.7 9.7 3.6e-44 150.9 6.7 2.0 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 KEG14178.1 - 5.8e-05 22.7 4.1 5.8e-05 22.7 2.8 2.8 1 1 2 3 3 3 1 Triose-phosphate Transporter family Kinesin PF00225.18 KEG14179.1 - 3.5e-59 200.2 0.1 1e-58 198.6 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain AAA_24 PF13479.1 KEG14179.1 - 0.0045 16.6 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KEG14179.1 - 0.022 14.8 0.0 0.24 11.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain Laminin_II PF06009.7 KEG14179.1 - 7.4 6.3 16.8 0.13 11.9 2.6 4.1 2 2 2 4 4 4 0 Laminin Domain II LSM14 PF12701.2 KEG14182.1 - 3.3e-29 100.5 0.8 4.5e-29 100.1 0.0 1.6 2 0 0 2 2 2 1 Scd6-like Sm domain SM-ATX PF14438.1 KEG14182.1 - 2.8e-05 23.9 0.0 4.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM PF01423.17 KEG14182.1 - 0.063 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 LSM domain GRP PF07172.6 KEG14182.1 - 0.083 13.3 10.4 0.15 12.5 7.2 1.4 1 0 0 1 1 1 0 Glycine rich protein family API5 PF05918.6 KEG14182.1 - 0.77 8.1 7.8 0.88 7.9 5.4 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) BAF1_ABF1 PF04684.8 KEG14182.1 - 1.1 7.9 6.2 1.3 7.7 4.3 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DnaJ PF00226.26 KEG14184.1 - 1.6e-05 24.5 0.0 2.8e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Y_phosphatase2 PF03162.8 KEG14185.1 - 4.2e-39 133.5 0.0 5.3e-39 133.2 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 KEG14185.1 - 9.9e-06 25.9 0.0 2e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 Tyrosine phosphatase family Flu_M2 PF00599.12 KEG14185.1 - 0.069 12.9 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Influenza Matrix protein (M2) AKAP2_C PF15304.1 KEG14186.1 - 0.098 12.2 0.4 0.13 11.9 0.3 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus Cyclin PF08613.6 KEG14187.1 - 0.00048 20.5 0.0 0.0007 20.0 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KEG14187.1 - 0.14 11.7 0.3 0.35 10.4 0.2 1.7 1 1 0 1 1 1 0 Cyclin, N-terminal domain DUF2475 PF10629.4 KEG14190.1 - 0.00081 19.5 1.0 0.0018 18.4 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2475) Raptor_N PF14538.1 KEG14191.1 - 8.8e-51 171.7 0.1 2.9e-50 170.1 0.0 1.9 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain HEAT PF02985.17 KEG14191.1 - 7.3e-06 25.6 4.1 0.05 13.6 0.0 3.7 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.1 KEG14191.1 - 9.6e-05 22.5 0.0 0.02 15.1 0.0 3.0 2 1 1 3 3 3 2 HEAT repeats Cnd1 PF12717.2 KEG14191.1 - 0.0024 17.7 0.2 1.4 8.7 0.0 2.3 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 KEG14191.1 - 0.45 11.0 3.4 1.1e+02 3.4 0.1 4.5 4 0 0 4 4 4 0 HEAT-like repeat RNA_pol_Rpb2_6 PF00562.23 KEG14192.1 - 7.4e-90 301.4 0.0 1e-89 301.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_3 PF04565.11 KEG14192.1 - 1.1e-15 57.1 0.0 2.6e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 KEG14192.1 - 1.3e-13 50.6 0.0 4.5e-13 48.9 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 KEG14192.1 - 7.7e-13 48.5 0.2 3.8e-12 46.2 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_1 PF04563.10 KEG14192.1 - 2.6e-08 33.0 0.0 5.5e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit PPR_2 PF13041.1 KEG14193.1 - 8.8e-05 22.4 0.4 0.00048 20.0 0.1 2.2 2 0 0 2 2 2 1 PPR repeat family PPR PF01535.15 KEG14193.1 - 0.0003 20.5 0.5 0.0098 15.8 0.0 2.6 2 0 0 2 2 2 1 PPR repeat DUF4164 PF13747.1 KEG14194.1 - 0.016 15.2 1.7 0.033 14.3 0.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) OprB PF04966.7 KEG14194.1 - 0.054 12.6 0.1 0.087 11.9 0.1 1.3 1 1 0 1 1 1 0 Carbohydrate-selective porin, OprB family zf-AN1 PF01428.11 KEG14195.1 - 0.0002 21.1 26.5 0.00032 20.5 5.8 2.5 2 0 0 2 2 2 2 AN1-like Zinc finger zf-LYAR PF08790.6 KEG14195.1 - 0.041 13.5 0.4 0.11 12.2 0.3 1.7 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger Nfu_N PF08712.6 KEG14195.1 - 0.08 12.5 0.0 8.3 6.1 0.0 2.6 1 1 1 2 2 2 0 Scaffold protein Nfu/NifU N terminal ENTH PF01417.15 KEG14196.1 - 8.5e-26 90.2 0.0 1.3e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 ENTH domain FAM176 PF14851.1 KEG14196.1 - 9.3 5.9 6.5 1.5 8.4 1.7 1.6 2 0 0 2 2 2 0 FAM176 family Ribosomal_L21e PF01157.13 KEG14197.1 - 1.4e-36 124.2 2.7 2.1e-36 123.6 1.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e Alpha_kinase PF02816.13 KEG14198.1 - 2e-51 174.3 0.0 2.7e-51 173.9 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family MAGE PF01454.14 KEG14199.1 - 0.14 11.4 0.0 0.45 9.8 0.0 1.8 2 0 0 2 2 2 0 MAGE family SF-assemblin PF06705.6 KEG14201.1 - 9.7e-05 21.6 10.4 0.0011 18.2 3.7 2.1 1 1 1 2 2 2 2 SF-assemblin/beta giardin SCAMP PF04144.8 KEG14202.1 - 2.4e-29 102.4 7.3 3.5e-29 101.9 5.1 1.1 1 0 0 1 1 1 1 SCAMP family DUF1516 PF07457.6 KEG14202.1 - 0.069 13.2 2.3 0.35 10.9 1.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1516) Tetraspannin PF00335.15 KEG14202.1 - 3.5 6.8 11.3 9 5.4 7.8 1.6 1 1 0 1 1 1 0 Tetraspanin family Dynein_light PF01221.13 KEG14203.1 - 2.7e-44 149.0 0.5 3.2e-44 148.8 0.3 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Peptidase_C3 PF00548.15 KEG14203.1 - 0.0072 16.1 0.0 0.0086 15.8 0.0 1.1 1 0 0 1 1 1 1 3C cysteine protease (picornain 3C) Imm28 PF15574.1 KEG14203.1 - 0.0093 15.5 0.1 0.012 15.1 0.1 1.2 1 0 0 1 1 1 1 Immunity protein 28 ECSIT PF06239.6 KEG14203.1 - 0.011 14.6 0.1 0.014 14.2 0.1 1.2 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway HTH_33 PF13592.1 KEG14203.1 - 0.052 13.1 0.0 0.091 12.3 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix Vasohibin PF14822.1 KEG14203.1 - 0.072 12.1 0.0 0.08 12.0 0.0 1.1 1 0 0 1 1 1 0 Vasohibin Ground-like PF04155.13 KEG14203.1 - 0.087 13.1 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 Ground-like domain Imm6 PF14434.1 KEG14203.1 - 0.097 12.3 0.0 0.15 11.7 0.0 1.3 1 1 0 1 1 1 0 Immunity protein Imm6 Ectatomin PF06457.6 KEG14203.1 - 0.11 12.2 0.1 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Ectatomin Herpes_BLRF2 PF05812.7 KEG14204.1 - 0.34 10.7 3.2 3 7.6 0.0 2.7 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein SM-ATX PF14438.1 KEG14205.1 - 0.01 15.7 1.9 0.015 15.2 0.1 2.0 2 1 0 2 2 2 0 Ataxin 2 SM domain Cytotoxic PF09000.5 KEG14205.1 - 0.073 13.1 0.2 0.35 10.9 0.0 2.0 2 0 0 2 2 2 0 Cytotoxic Pkinase PF00069.20 KEG14206.1 - 5.7e-59 199.3 0.0 9.5e-59 198.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG14206.1 - 7e-28 97.4 0.0 3.7e-26 91.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG14206.1 - 3.2e-08 32.9 0.0 0.0013 17.7 0.0 2.8 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.9 KEG14206.1 - 0.0033 16.5 0.2 0.005 15.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEG14206.1 - 0.0046 16.7 0.2 0.0069 16.1 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KEG14206.1 - 0.0069 15.2 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 KEG14206.1 - 0.078 11.7 0.2 0.14 10.9 0.0 1.4 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase PP2C PF00481.16 KEG14207.1 - 6.5e-69 232.1 0.0 7.9e-69 231.8 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KEG14207.1 - 2.7e-05 23.6 0.0 4.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KEG14207.1 - 0.00092 18.9 0.0 0.012 15.3 0.0 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) DUF327 PF03885.8 KEG14208.1 - 0.011 15.5 0.7 1.1 9.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF327) Mito_carr PF00153.22 KEG14209.1 - 4.7e-91 298.6 17.2 8.7e-22 76.6 0.0 6.4 5 2 1 6 6 6 6 Mitochondrial carrier protein TPR_11 PF13414.1 KEG14210.1 - 1.6e-37 126.9 18.9 1.4e-16 59.9 0.4 6.3 3 3 2 6 6 6 4 TPR repeat TPR_1 PF00515.23 KEG14210.1 - 1.4e-22 78.2 13.1 4.9e-06 25.9 0.0 6.8 6 0 0 6 6 6 3 Tetratricopeptide repeat DnaJ PF00226.26 KEG14210.1 - 3.5e-20 71.5 2.4 9.1e-20 70.1 0.5 2.3 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.12 KEG14210.1 - 1.2e-18 65.4 24.9 2e-05 24.1 0.0 8.4 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 KEG14210.1 - 2.7e-14 53.3 11.2 0.0004 20.9 0.1 5.8 3 2 2 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.1 KEG14210.1 - 8.4e-12 43.9 3.2 0.2 11.5 0.2 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 KEG14210.1 - 9.5e-10 38.2 14.6 0.19 12.4 0.0 7.8 5 2 2 8 8 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEG14210.1 - 2.7e-09 37.2 15.3 0.084 13.2 0.1 6.3 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 KEG14210.1 - 4.7e-09 36.0 13.6 0.0045 16.9 0.2 5.2 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_9 PF13371.1 KEG14210.1 - 3.7e-08 33.0 3.2 0.012 15.4 0.4 4.6 4 1 2 6 6 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 KEG14210.1 - 3.1e-07 29.6 9.0 0.11 12.3 0.1 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_15 PF13429.1 KEG14210.1 - 0.00042 19.4 9.9 0.011 14.8 1.9 3.8 3 2 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 KEG14210.1 - 0.0025 17.6 6.7 5.3 6.9 0.0 5.4 3 2 2 5 5 5 1 MIT (microtubule interacting and transport) domain TPR_17 PF13431.1 KEG14210.1 - 0.0074 16.3 8.9 11 6.5 0.0 6.2 7 1 0 7 7 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KEG14210.1 - 0.0077 16.0 1.4 0.88 9.4 0.0 4.3 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 KEG14210.1 - 0.016 15.6 4.2 9.6 6.9 0.0 5.3 5 0 0 5 5 4 0 Tetratricopeptide repeat Orthopox_F7 PF05813.7 KEG14210.1 - 0.078 12.8 0.2 0.92 9.4 0.0 2.6 3 0 0 3 3 2 0 Orthopoxvirus F7 protein PPR PF01535.15 KEG14210.1 - 0.093 12.7 0.3 47 4.2 0.0 3.8 3 0 0 3 3 3 0 PPR repeat Tox-REase-2 PF15646.1 KEG14210.1 - 0.11 12.3 0.6 0.81 9.5 0.1 2.6 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 2 HemY_N PF07219.8 KEG14210.1 - 1.1 8.7 10.2 0.15 11.5 0.2 3.7 4 0 0 4 4 4 0 HemY protein N-terminus zf-C2HC_2 PF13913.1 KEG14211.1 - 5.6e-12 44.9 10.4 1.1e-08 34.5 1.6 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.1 KEG14211.1 - 0.1 12.9 1.4 1.3 9.4 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double domain Lar_restr_allev PF14354.1 KEG14211.1 - 0.2 12.0 1.0 1.2 9.5 0.0 2.4 2 0 0 2 2 2 0 Restriction alleviation protein Lar zf-C2H2_6 PF13912.1 KEG14211.1 - 0.28 11.1 2.7 7.9 6.5 0.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Apc11 PF12861.2 KEG14212.1 - 0.043 13.6 0.8 0.073 12.9 0.6 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Dus PF01207.12 KEG14213.1 - 3.5e-31 108.1 0.7 4.5e-30 104.5 0.5 2.1 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Sec1 PF00995.18 KEG14214.1 - 2.3e-129 432.5 1.4 2.7e-129 432.3 1.0 1.0 1 0 0 1 1 1 1 Sec1 family UPF0167 PF03691.9 KEG14214.1 - 0.098 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) YadA_head PF05658.9 KEG14215.1 - 7.7 6.9 12.1 0.25 11.6 0.3 2.7 2 0 0 2 2 2 0 Head domain of trimeric autotransporter adhesin FAST_1 PF06743.10 KEG14216.1 - 0.00075 19.1 0.2 0.046 13.4 0.0 3.2 3 0 0 3 3 3 1 FAST kinase-like protein, subdomain 1 TFIIA_gamma_N PF02268.11 KEG14217.1 - 0.018 14.5 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit, helical domain Aa_trans PF01490.13 KEG14218.1 - 2.5e-50 171.1 36.7 2.9e-50 170.9 25.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KEG14218.1 - 0.004 16.0 36.3 0.026 13.3 25.2 2.0 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family Effector_1 PF04518.7 KEG14219.1 - 0.082 11.8 0.2 0.1 11.5 0.2 1.1 1 0 0 1 1 1 0 Effector from type III secretion system Mnd1 PF03962.10 KEG14219.1 - 0.13 11.9 0.2 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 Mnd1 family KaiC PF06745.8 KEG14219.1 - 0.18 10.8 0.4 0.71 8.9 0.3 1.7 2 0 0 2 2 2 0 KaiC Spore_III_AB PF09548.5 KEG14219.1 - 0.3 10.8 2.8 0.68 9.6 1.8 1.6 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) PDZ PF00595.19 KEG14220.1 - 2.2e-05 24.5 0.0 8.1e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KEG14220.1 - 3.9e-05 23.4 1.7 5.6e-05 22.9 0.2 2.0 2 0 0 2 2 2 1 PDZ domain GRASP55_65 PF04495.9 KEG14220.1 - 0.0052 16.7 0.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 2 GRASP55/65 PDZ-like domain Apolipoprotein PF01442.13 KEG14220.1 - 0.044 13.2 1.4 0.11 11.9 1.0 1.7 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Lipase_GDSL_2 PF13472.1 KEG14225.1 - 1.2e-08 35.3 0.0 2.6e-08 34.1 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Cu-binding_MopE PF11617.3 KEG14225.1 - 7.8e-05 22.3 2.8 0.00018 21.1 1.9 1.6 1 0 0 1 1 1 1 Protein metal binding site Lipase_GDSL PF00657.17 KEG14225.1 - 0.00076 19.3 0.0 0.0039 17.0 0.0 2.2 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase Pantoate_ligase PF02569.10 KEG14226.1 - 7e-96 320.2 0.0 7.8e-96 320.0 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase PIP5K PF01504.13 KEG14227.1 - 3.9e-58 196.5 0.0 4.9e-58 196.1 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF106 PF01956.11 KEG14228.1 - 2.5e-47 160.5 6.4 1.3e-46 158.1 4.4 1.8 1 1 0 1 1 1 1 Integral membrane protein DUF106 Hom_end_hint PF05203.11 KEG14229.1 - 0.11 12.2 0.1 0.18 11.5 0.1 1.3 1 1 0 1 1 1 0 Hom_end-associated Hint IQ PF00612.22 KEG14229.1 - 0.11 12.1 3.2 0.3 10.8 0.3 2.9 2 0 0 2 2 2 0 IQ calmodulin-binding motif DUF212 PF02681.9 KEG14230.1 - 0.085 12.5 0.2 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 Divergent PAP2 family NESP55 PF06390.7 KEG14230.1 - 0.11 11.8 0.1 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) zf-DNL PF05180.7 KEG14230.1 - 0.13 11.9 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 DNL zinc finger Cortex-I_coil PF09304.5 KEG14231.1 - 0.00011 22.1 2.8 0.0012 18.8 0.3 2.3 2 0 0 2 2 2 1 Cortexillin I, coiled coil DUF2968 PF11180.3 KEG14231.1 - 0.0023 17.3 3.5 0.0023 17.3 2.4 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2968) HrcA PF01628.16 KEG14231.1 - 0.0054 16.3 0.8 0.011 15.2 0.1 1.8 2 0 0 2 2 2 1 HrcA protein C terminal domain CENP-F_leu_zip PF10473.4 KEG14231.1 - 0.041 13.7 1.2 2.6 7.8 0.1 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4105 PF13387.1 KEG14231.1 - 0.14 11.3 0.3 0.27 10.3 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) Filament PF00038.16 KEG14231.1 - 0.15 11.4 3.4 0.29 10.5 0.4 2.1 2 0 0 2 2 2 0 Intermediate filament protein DivIVA PF05103.8 KEG14231.1 - 0.19 11.7 4.4 2.3 8.2 0.0 2.9 3 0 0 3 3 3 0 DivIVA protein HR1 PF02185.11 KEG14231.1 - 0.35 10.6 4.4 0.21 11.3 1.0 2.1 2 0 0 2 2 2 0 Hr1 repeat IncA PF04156.9 KEG14231.1 - 0.52 9.8 4.0 0.7 9.4 0.6 2.3 2 0 0 2 2 2 0 IncA protein Tropomyosin_1 PF12718.2 KEG14231.1 - 0.67 9.8 6.5 4.5 7.1 1.0 2.4 2 0 0 2 2 2 0 Tropomyosin like EzrA PF06160.7 KEG14231.1 - 0.67 8.0 3.2 0.35 9.0 0.2 1.9 3 0 0 3 3 3 0 Septation ring formation regulator, EzrA KfrA_N PF11740.3 KEG14231.1 - 1.4 9.4 15.9 0.38 11.1 4.8 2.9 3 0 0 3 3 2 0 Plasmid replication region DNA-binding N-term DUF904 PF06005.7 KEG14231.1 - 2 8.7 7.1 2.3 8.6 2.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF904) SlyX PF04102.7 KEG14231.1 - 3.7 8.0 6.3 0.76 10.1 0.4 2.7 2 1 1 3 3 3 0 SlyX BMFP PF04380.8 KEG14231.1 - 4 7.6 9.5 12 6.0 0.2 2.5 2 0 0 2 2 2 0 Membrane fusogenic activity GSP_synth PF03738.9 KEG14232.1 - 2.9e-28 97.9 0.2 5.1e-28 97.1 0.1 1.4 1 0 0 1 1 1 1 Glutathionylspermidine synthase preATP-grasp CHAP PF05257.11 KEG14232.1 - 2.7e-19 69.0 0.0 5.2e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 CHAP domain Mre11_DNA_bind PF04152.9 KEG14234.1 - 1e-34 119.9 0.0 3e-34 118.4 0.0 1.8 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 KEG14234.1 - 3.7e-17 62.4 2.1 4.8e-09 35.8 0.3 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase DUF846 PF05832.7 KEG14236.1 - 1.8e-43 147.6 9.8 2.2e-43 147.3 6.8 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) CAP_N PF01213.14 KEG14236.1 - 4 6.6 7.2 5.9 6.0 5.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal zf-MIZ PF02891.15 KEG14237.1 - 8.2e-20 70.0 0.4 1.7e-19 69.0 0.3 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-C3HC4_2 PF13923.1 KEG14237.1 - 0.013 15.5 2.4 0.46 10.5 0.3 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEG14237.1 - 0.021 14.6 0.8 0.021 14.6 0.6 2.1 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_3 PF13920.1 KEG14237.1 - 0.085 12.5 2.9 0.14 11.8 0.2 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Glypican PF01153.14 KEG14237.1 - 2.9 6.3 4.8 4.4 5.7 3.3 1.2 1 0 0 1 1 1 0 Glypican CDC45 PF02724.9 KEG14237.1 - 4 5.3 6.3 6.4 4.6 4.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 KEG14237.1 - 5.5 6.5 8.9 2.1 7.8 3.0 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region CHCH PF06747.8 KEG14238.1 - 5.2 7.1 13.7 0.55 10.2 0.2 3.9 4 0 0 4 4 4 0 CHCH domain PPR PF01535.15 KEG14239.1 - 0.023 14.6 0.0 9.2 6.4 0.0 3.7 4 0 0 4 4 4 0 PPR repeat HPIH PF13323.1 KEG14239.1 - 0.041 13.5 0.0 0.084 12.5 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain with HPIH motif PPR_3 PF13812.1 KEG14239.1 - 0.13 12.5 3.8 11 6.5 0.0 4.3 4 0 0 4 4 4 0 Pentatricopeptide repeat domain Cyto_heme_lyase PF01265.12 KEG14240.1 - 0.023 14.2 0.0 0.041 13.4 0.0 1.5 1 1 0 1 1 1 0 Cytochrome c/c1 heme lyase MLANA PF14991.1 KEG14240.1 - 7.3 6.6 14.3 0.14 12.2 0.4 3.8 3 1 0 4 4 4 0 Protein melan-A POP1 PF06978.6 KEG14241.1 - 0.084 12.5 6.5 0.11 12.1 4.5 1.1 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 Pkinase PF00069.20 KEG14242.1 - 1.4e-53 181.7 0.0 4.1e-46 157.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEG14242.1 - 7.4e-26 90.7 0.0 2.9e-22 79.0 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KEG14242.1 - 7.2e-05 21.8 0.0 0.00011 21.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DUF3449 PF11931.3 KEG14242.1 - 0.077 12.4 2.2 10 5.5 1.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) Seadorna_VP7 PF07387.6 KEG14242.1 - 0.15 10.8 0.0 0.26 10.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Dpy-30 PF05186.8 KEG14243.1 - 1.3e-06 27.7 0.2 2.4e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 Dpy-30 motif ADK PF00406.17 KEG14243.1 - 0.0065 16.3 0.0 0.029 14.2 0.0 2.1 1 0 0 1 1 1 1 Adenylate kinase SDA1 PF05285.7 KEG14243.1 - 0.82 8.8 51.0 0.95 8.6 19.1 3.5 3 0 0 3 3 3 0 SDA1 IFT43 PF15305.1 KEG14244.1 - 1.5e-08 34.7 0.7 5.9e-08 32.8 0.5 2.1 1 0 0 1 1 1 1 Intraflagellar transport protein 43 LSM PF01423.17 KEG14245.1 - 2.8e-15 55.5 0.3 3.5e-15 55.3 0.2 1.1 1 0 0 1 1 1 1 LSM domain FtsJ PF01728.14 KEG14246.1 - 2.8e-55 187.1 0.0 4.7e-55 186.3 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Spb1_C PF07780.7 KEG14246.1 - 5.9e-29 101.0 26.3 5.9e-29 101.0 18.2 4.5 3 2 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.3 KEG14246.1 - 2.1e-28 98.8 7.5 2.1e-28 98.8 5.2 3.7 4 1 0 4 4 4 1 Domain of unknown function (DUF3381) RabGAP-TBC PF00566.13 KEG14247.1 - 8.1e-26 90.8 0.0 1.2e-24 86.9 0.0 2.3 1 1 0 1 1 1 1 Rab-GTPase-TBC domain TRAM1 PF08390.6 KEG14247.1 - 0.14 11.7 0.3 0.39 10.2 0.1 1.9 2 0 0 2 2 2 0 TRAM1-like protein Pet191_N PF10203.4 KEG14248.1 - 2.6e-16 59.4 2.3 3.4e-16 59.0 1.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 HATPase_c PF02518.21 KEG14249.1 - 9.7e-06 25.2 0.0 2.8e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Dynein_heavy PF03028.10 KEG14252.1 - 3.6e-219 729.4 0.0 6.9e-219 728.4 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N1 PF08385.7 KEG14252.1 - 1.2e-142 476.2 4.3 1.2e-142 476.2 3.0 3.2 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 KEG14252.1 - 5e-120 400.7 4.7 5e-120 400.7 3.2 3.1 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 KEG14252.1 - 3.2e-102 340.9 0.0 8.5e-102 339.5 0.0 1.8 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 KEG14252.1 - 2.1e-76 256.4 0.0 4e-76 255.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.2 KEG14252.1 - 4.3e-55 186.7 0.1 1.4e-54 185.0 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_9 PF12781.2 KEG14252.1 - 4.7e-48 163.0 0.0 1e-47 161.9 0.0 1.6 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 KEG14252.1 - 9.9e-41 139.6 12.2 1.2e-40 139.2 7.6 1.8 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 KEG14252.1 - 3.2e-28 98.1 0.9 2.9e-07 30.2 0.0 7.3 6 1 0 6 6 6 4 AAA domain (dynein-related subfamily) AAA PF00004.24 KEG14252.1 - 1.3e-09 38.3 4.3 0.56 10.4 0.0 6.6 6 0 0 6 6 5 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEG14252.1 - 8.7e-08 32.3 11.8 0.029 14.3 0.0 7.3 7 1 0 7 7 6 2 AAA ATPase domain AAA_22 PF13401.1 KEG14252.1 - 1e-06 28.9 5.3 0.25 11.5 0.0 5.8 6 0 0 6 6 4 2 AAA domain ABC_tran PF00005.22 KEG14252.1 - 0.00024 21.3 1.2 1.1 9.6 0.0 4.3 4 0 0 4 4 3 1 ABC transporter AAA_17 PF13207.1 KEG14252.1 - 0.00027 21.7 1.0 4.2 8.2 0.0 5.0 4 0 0 4 4 4 1 AAA domain AAA_29 PF13555.1 KEG14252.1 - 0.00045 19.6 0.5 0.067 12.7 0.0 3.4 3 0 0 3 3 3 1 P-loop containing region of AAA domain Sigma54_activat PF00158.21 KEG14252.1 - 0.0029 17.0 0.1 1.5 8.2 0.0 3.2 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_33 PF13671.1 KEG14252.1 - 0.003 17.4 0.9 4.5 7.1 0.0 5.2 5 0 0 5 5 5 1 AAA domain DUF258 PF03193.11 KEG14252.1 - 0.0031 16.7 5.5 0.033 13.3 0.0 3.6 4 0 0 4 4 4 1 Protein of unknown function, DUF258 RNA_helicase PF00910.17 KEG14252.1 - 0.011 15.9 0.2 11 6.1 0.0 3.9 3 0 0 3 3 3 0 RNA helicase MobB PF03205.9 KEG14252.1 - 0.012 15.2 0.1 2.9 7.6 0.1 3.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 KEG14252.1 - 0.17 11.6 2.2 13 5.5 0.1 4.0 4 0 0 4 4 4 0 Part of AAA domain SMC_N PF02463.14 KEG14252.1 - 1 8.5 0.0 3.7 6.7 0.0 1.9 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain TPR_11 PF13414.1 KEG14253.1 - 2.3e-23 81.6 12.4 3.5e-11 42.5 0.2 5.0 4 1 1 5 5 5 4 TPR repeat DnaJ PF00226.26 KEG14253.1 - 1.3e-16 60.0 0.2 2.6e-16 59.1 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.23 KEG14253.1 - 6.3e-16 57.2 3.1 0.00011 21.6 0.2 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEG14253.1 - 1.3e-12 46.6 14.2 0.0026 17.5 0.1 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 KEG14253.1 - 3.2e-06 27.6 11.1 0.84 10.3 0.0 5.8 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 KEG14253.1 - 3.6e-05 23.6 0.9 0.091 13.0 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 KEG14253.1 - 0.0004 20.2 13.5 0.079 12.9 0.6 5.5 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 KEG14253.1 - 0.00061 20.1 12.1 1.1 10.0 0.1 6.2 5 1 2 7 7 6 1 Tetratricopeptide repeat TPR_15 PF13429.1 KEG14253.1 - 0.0011 18.0 0.1 0.0025 16.9 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat MIT PF04212.13 KEG14253.1 - 0.0048 16.7 0.1 0.24 11.2 0.0 3.5 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_19 PF14559.1 KEG14253.1 - 0.032 14.5 3.6 13 6.1 0.0 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 KEG14253.1 - 0.1 12.4 3.3 3.3 7.6 0.0 4.4 6 0 0 6 6 5 0 Tetratricopeptide repeat LSM PF01423.17 KEG14254.1 - 1e-11 44.1 0.3 1.3e-11 43.8 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KEG14254.1 - 3.6e-06 26.8 0.3 5.1e-06 26.3 0.2 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Tail_tube PF10618.4 KEG14254.1 - 0.052 13.2 0.0 0.073 12.8 0.0 1.2 1 0 0 1 1 1 0 Phage tail tube protein MIP PF00230.15 KEG14255.1 - 6.6e-30 104.2 17.7 6.6e-29 100.9 12.3 2.0 1 1 0 1 1 1 1 Major intrinsic protein F-box-like PF12937.2 KEG14256.1 - 0.0017 18.0 1.9 0.015 14.9 0.3 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KEG14256.1 - 0.016 14.8 0.0 0.041 13.5 0.0 1.7 1 0 0 1 1 1 0 F-box domain DUF2666 PF10869.3 KEG14257.1 - 0.062 13.3 3.7 0.12 12.4 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2666) Phage_min_cap2 PF06152.6 KEG14257.1 - 0.07 12.0 7.1 0.13 11.2 5.0 1.4 1 0 0 1 1 1 0 Phage minor capsid protein 2 DUF812 PF05667.6 KEG14257.1 - 0.79 8.1 18.6 1.2 7.5 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) YjcZ PF13990.1 KEG14257.1 - 1.1 8.3 11.3 0.82 8.7 5.9 2.0 2 0 0 2 2 2 0 YjcZ-like protein GAS PF13851.1 KEG14257.1 - 1.3 8.1 19.5 5.4 6.1 0.2 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4168 PF13767.1 KEG14257.1 - 2.7 8.6 7.9 1.7 9.2 3.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4168) TPR_MLP1_2 PF07926.7 KEG14257.1 - 2.8 7.6 22.7 7.2 6.3 11.8 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF2536 PF10750.4 KEG14257.1 - 3.4 7.3 11.0 0.44 10.1 0.9 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2536) TPR_11 PF13414.1 KEG14258.1 - 4.4e-16 58.2 4.1 8.8e-10 38.0 0.5 2.8 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 KEG14258.1 - 5.6e-14 51.0 5.0 0.00011 21.6 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEG14258.1 - 1.3e-11 43.4 3.1 0.0083 15.9 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 KEG14258.1 - 1.8e-07 30.9 2.4 0.00015 21.6 1.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEG14258.1 - 2.6e-06 27.9 0.8 0.027 15.1 0.0 2.4 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KEG14258.1 - 8.5e-06 25.1 2.0 0.86 9.5 0.6 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat BTAD PF03704.12 KEG14258.1 - 0.00021 21.6 0.9 0.39 11.0 0.1 2.2 2 0 0 2 2 2 2 Bacterial transcriptional activator domain Apc3 PF12895.2 KEG14258.1 - 0.00041 20.4 1.4 0.009 16.1 0.3 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 KEG14258.1 - 0.00084 19.7 0.2 0.72 10.6 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 KEG14258.1 - 0.0011 18.9 0.1 0.29 11.4 0.0 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEG14258.1 - 0.0024 18.1 0.0 1.1 9.6 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Arfaptin PF06456.8 KEG14258.1 - 0.0032 16.8 0.0 0.0046 16.3 0.0 1.2 1 0 0 1 1 1 1 Arfaptin-like domain DUF2365 PF10157.4 KEG14258.1 - 0.0081 16.0 0.1 0.042 13.7 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2365) TPR_6 PF13174.1 KEG14258.1 - 0.0083 16.5 0.3 1.8 9.1 0.2 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF2464 PF10240.4 KEG14258.1 - 0.0092 15.3 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2464) TPR_9 PF13371.1 KEG14258.1 - 0.023 14.5 0.2 4.6 7.1 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KEG14258.1 - 0.048 13.4 1.2 4.1 7.4 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_L14 PF00238.14 KEG14259.1 - 2.6e-13 49.8 0.0 8.3e-13 48.1 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L14p/L23e Apolipoprotein PF01442.13 KEG14260.1 - 0.066 12.7 0.7 0.084 12.3 0.5 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Complex1_LYR PF05347.10 KEG14260.1 - 0.095 12.5 0.1 0.22 11.3 0.1 1.6 1 0 0 1 1 1 0 Complex 1 protein (LYR family) DUF486 PF04342.7 KEG14260.1 - 0.14 12.2 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF486 WD40 PF00400.27 KEG14262.1 - 1.5e-08 34.2 0.4 3.1e-05 23.6 0.0 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat Apc3 PF12895.2 KEG14262.1 - 0.016 15.3 1.8 0.42 10.7 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 PGM_PMM_IV PF00408.15 KEG14263.1 - 6.8e-06 26.0 0.0 1.3e-05 25.0 0.0 1.6 1 1 1 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_I PF02878.11 KEG14264.1 - 5.7e-40 136.0 0.0 1.3e-39 134.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 KEG14264.1 - 1.5e-19 70.1 0.1 5.3e-19 68.4 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 KEG14264.1 - 1.7e-12 47.3 0.1 3.6e-12 46.3 0.1 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Actin PF00022.14 KEG14266.1 - 1.6e-45 155.1 0.0 1.9e-45 154.9 0.0 1.1 1 0 0 1 1 1 1 Actin Chordopox_RPO7 PF05864.7 KEG14266.1 - 0.015 15.3 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) zinc_ribbon_2 PF13240.1 KEG14267.1 - 0.024 14.1 1.7 0.024 14.1 1.2 2.9 4 0 0 4 4 4 0 zinc-ribbon domain C1_2 PF03107.11 KEG14267.1 - 0.025 14.6 4.0 0.025 14.6 2.7 2.2 3 0 0 3 3 3 0 C1 domain Elf1 PF05129.8 KEG14267.1 - 0.38 10.4 5.2 1.3 8.7 2.7 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like DUF2453 PF10507.4 KEG14268.1 - 2.9e-33 113.9 0.6 3.8e-33 113.6 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2453) SGT1 PF07093.6 KEG14268.1 - 0.11 10.8 0.0 0.13 10.6 0.0 1.0 1 0 0 1 1 1 0 SGT1 protein Aa_trans PF01490.13 KEG14269.1 - 3.3e-35 121.3 30.5 4e-35 121.1 21.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CcmE PF03100.10 KEG14269.1 - 0.14 11.7 0.0 0.42 10.1 0.0 1.8 1 0 0 1 1 1 0 CcmE SET PF00856.23 KEG14270.1 - 1.4e-06 28.7 0.1 0.0015 18.8 0.0 2.3 1 1 0 1 1 1 1 SET domain 4HBT PF03061.17 KEG14271.1 - 0.011 15.7 0.1 0.022 14.8 0.1 1.5 1 0 0 1 1 1 0 Thioesterase superfamily DUF4442 PF14539.1 KEG14271.1 - 0.021 14.8 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) DUF2042 PF09743.4 KEG14272.1 - 6.6e-87 291.2 0.1 1.1e-86 290.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2042) AFG1_ATPase PF03969.11 KEG14273.1 - 7e-57 192.8 0.0 2e-55 188.0 0.0 2.0 2 0 0 2 2 2 2 AFG1-like ATPase WBS28 PF15164.1 KEG14273.1 - 0.014 14.4 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Williams-Beuren syndrome chromosomal region 28 protein homologue NIF PF03031.13 KEG14274.1 - 6.9e-34 116.8 0.0 9e-34 116.4 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Adaptin_N PF01602.15 KEG14275.1 - 6.2e-109 364.7 0.3 8.5e-109 364.2 0.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KEG14275.1 - 2.5e-15 56.7 0.3 8.1e-15 55.1 0.0 2.0 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KEG14275.1 - 1.1e-10 41.6 0.2 4.4e-07 30.0 0.0 4.1 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.17 KEG14275.1 - 0.0048 16.8 7.5 0.64 10.2 0.0 5.3 6 0 0 6 6 6 1 HEAT repeat DRIM PF07539.7 KEG14275.1 - 0.054 12.9 0.1 0.52 9.7 0.0 2.8 2 0 0 2 2 2 0 Down-regulated in metastasis VHS PF00790.14 KEG14275.1 - 0.055 13.1 0.0 0.16 11.5 0.0 1.8 1 0 0 1 1 1 0 VHS domain OSCP PF00213.13 KEG14276.1 - 1e-08 35.2 2.5 2.1e-07 30.9 1.5 2.5 2 1 0 2 2 2 1 ATP synthase delta (OSCP) subunit Lyase_aromatic PF00221.14 KEG14277.1 - 3.1e-184 612.8 0.1 3.6e-184 612.6 0.0 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase Peptidase_S9_N PF02897.10 KEG14278.1 - 5.4e-99 331.5 0.0 6.9e-99 331.2 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 KEG14278.1 - 8.6e-65 217.9 0.0 1.3e-64 217.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 KEG14278.1 - 1.6e-05 24.4 0.0 3.9e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 Putative esterase Abhydrolase_5 PF12695.2 KEG14278.1 - 0.00031 20.5 0.0 0.00067 19.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 KEG14278.1 - 0.0041 16.8 0.0 0.0069 16.1 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.15 KEG14278.1 - 0.02 14.4 0.0 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KEG14278.1 - 0.035 13.6 0.0 0.073 12.6 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 KEG14278.1 - 0.1 11.9 0.8 0.21 10.9 0.0 1.9 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 KEG14278.1 - 0.11 10.9 0.0 0.18 10.2 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) AAA_17 PF13207.1 KEG14280.1 - 0.0075 17.0 1.4 0.036 14.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain EF-hand_6 PF13405.1 KEG14280.1 - 0.035 13.9 0.0 0.37 10.7 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain Mito_carr PF00153.22 KEG14281.1 - 4.9e-53 176.8 0.7 1.7e-16 59.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SpoV PF08183.6 KEG14281.1 - 0.079 12.6 0.3 1.3 8.8 0.1 2.4 2 0 0 2 2 2 0 Stage V sporulation protein family Rep_fac_C PF08542.6 KEG14282.1 - 2.3e-18 65.9 0.0 5.3e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KEG14282.1 - 1.2e-15 57.5 0.0 1.7e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 KEG14282.1 - 1.6e-09 38.0 0.0 5.2e-09 36.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 KEG14282.1 - 1.5e-05 23.9 0.0 2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein Sigma54_activ_2 PF14532.1 KEG14282.1 - 2.9e-05 24.1 0.0 0.041 13.9 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.1 KEG14282.1 - 0.00057 19.9 0.0 0.022 14.7 0.0 2.8 2 2 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 KEG14282.1 - 0.00068 19.3 0.1 0.0041 16.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 KEG14282.1 - 0.0078 15.8 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KEG14282.1 - 0.012 14.7 1.1 0.46 9.5 0.0 2.6 2 1 1 3 3 3 0 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KEG14282.1 - 0.013 15.5 0.2 0.13 12.3 0.1 2.5 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.21 KEG14282.1 - 0.021 14.3 0.0 0.51 9.7 0.0 2.5 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_10 PF12846.2 KEG14282.1 - 0.052 12.9 0.0 0.093 12.1 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain DUF815 PF05673.8 KEG14282.1 - 0.1 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_16 PF13191.1 KEG14284.1 - 0.00046 20.2 0.5 0.0058 16.6 0.3 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KEG14284.1 - 0.0043 17.1 0.0 0.013 15.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KEG14284.1 - 0.011 15.7 0.0 0.029 14.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KEG14284.1 - 0.058 12.7 0.0 0.19 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KEG14284.1 - 0.073 13.8 0.0 0.29 11.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KEG14284.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KEG14284.1 - 0.13 11.9 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase SRPRB PF09439.5 KEG14284.1 - 0.17 11.0 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Solute_trans_a PF03619.11 KEG14285.1 - 1.6e-86 290.0 18.4 2e-86 289.7 12.7 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Lipoprotein_6 PF01441.14 KEG14286.1 - 0.0046 16.8 6.6 0.0046 16.8 4.6 1.4 1 1 0 1 1 1 1 Lipoprotein TMF_DNA_bd PF12329.3 KEG14286.1 - 0.012 15.3 19.3 0.032 14.0 4.4 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding GldM_N PF12081.3 KEG14286.1 - 0.025 14.1 2.1 0.032 13.7 1.5 1.3 1 0 0 1 1 1 0 GldM N-terminal domain DUF3829 PF12889.2 KEG14286.1 - 0.046 12.9 2.2 0.053 12.7 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) Mnd1 PF03962.10 KEG14286.1 - 0.055 13.1 18.2 0.13 11.9 12.3 1.7 1 1 0 1 1 1 0 Mnd1 family Mer2 PF09074.5 KEG14286.1 - 0.068 13.0 11.1 0.048 13.5 6.8 1.4 1 1 0 1 1 1 0 Mer2 IMD PF08397.6 KEG14286.1 - 0.091 12.0 17.2 0.09 12.0 1.9 2.1 1 1 1 2 2 2 0 IRSp53/MIM homology domain CALCOCO1 PF07888.6 KEG14286.1 - 0.24 9.6 19.4 0.28 9.4 13.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Seryl_tRNA_N PF02403.17 KEG14286.1 - 0.34 10.9 19.1 0.57 10.2 3.9 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 KEG14286.1 - 0.43 10.1 25.4 0.45 10.0 14.7 2.0 1 1 1 2 2 2 0 IncA protein CENP-K PF11802.3 KEG14286.1 - 0.64 9.2 14.8 0.81 8.8 10.3 1.1 1 0 0 1 1 1 0 Centromere-associated protein K DUF148 PF02520.12 KEG14286.1 - 0.77 9.5 8.5 0.64 9.8 4.6 1.8 1 1 1 2 2 2 0 Domain of unknown function DUF148 GrpE PF01025.14 KEG14286.1 - 0.78 9.2 12.2 1.2 8.6 8.4 1.4 1 1 0 1 1 1 0 GrpE End3 PF12761.2 KEG14286.1 - 0.9 9.1 17.5 0.24 11.0 9.2 2.0 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Mu-like_Pro PF10123.4 KEG14286.1 - 0.92 8.8 12.1 1.2 8.4 6.8 1.8 1 1 1 2 2 2 0 Mu-like prophage I protein Phage_GPO PF05929.6 KEG14286.1 - 1 8.5 9.3 1.2 8.2 6.5 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase TBPIP PF07106.8 KEG14286.1 - 1.1 8.7 16.6 2.4 7.6 8.1 2.2 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) GBP_C PF02841.9 KEG14286.1 - 1.2 8.3 17.6 1.4 8.0 12.2 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain NPV_P10 PF05531.7 KEG14286.1 - 1.2 9.3 6.5 1.7 8.9 2.4 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein TMPIT PF07851.8 KEG14286.1 - 1.5 7.7 7.6 1.7 7.6 5.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein Bestrophin PF01062.16 KEG14286.1 - 1.8 7.4 4.4 2.1 7.1 3.0 1.1 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel DUF342 PF03961.8 KEG14286.1 - 2.2 6.5 12.0 1.7 6.9 7.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) DivIVA PF05103.8 KEG14286.1 - 2.5 8.1 14.9 2.7 8.0 9.8 1.4 1 1 0 1 1 1 0 DivIVA protein GAS PF13851.1 KEG14286.1 - 4 6.5 22.4 5.9 6.0 9.4 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.6 KEG14286.1 - 4.1 5.9 17.7 5.5 5.5 12.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ALMT PF11744.3 KEG14286.1 - 5.7 5.4 6.4 6.8 5.2 4.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Ly49 PF08391.5 KEG14286.1 - 5.8 7.0 11.6 5 7.2 6.8 1.9 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region Prefoldin PF02996.12 KEG14286.1 - 8.1 6.1 17.5 0.33 10.6 2.4 3.0 2 1 0 3 3 3 0 Prefoldin subunit HAUS-augmin3 PF14932.1 KEG14286.1 - 8.6 5.4 20.0 3.7 6.6 11.4 1.7 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 CENP-H PF05837.7 KEG14286.1 - 9.7 6.4 19.8 6.6 6.9 8.7 2.5 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Cyt-b5 PF00173.23 KEG14287.1 - 4.1e-12 45.7 0.0 4.9e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FtsJ PF01728.14 KEG14288.1 - 2.1e-26 93.0 0.0 2.8e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Metalloenzyme PF01676.13 KEG14290.1 - 1.3e-70 237.6 0.0 1.5e-70 237.4 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 KEG14290.1 - 6.5e-62 208.7 0.0 9e-62 208.3 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.17 KEG14290.1 - 5.2e-05 22.7 0.0 0.0001 21.7 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4448 PF14610.1 KEG14291.1 - 0.12 11.8 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) CcoS PF03597.10 KEG14291.1 - 0.14 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type DUF947 PF06102.7 KEG14295.1 - 2.5e-17 63.2 11.1 7.2e-17 61.7 7.7 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF947) COPI_assoc PF08507.5 KEG14296.1 - 7.5e-18 64.5 10.0 9.9e-18 64.1 6.9 1.1 1 0 0 1 1 1 1 COPI associated protein CDV3 PF15359.1 KEG14296.1 - 0.068 13.2 0.1 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 EF-hand_8 PF13833.1 KEG14297.1 - 0.068 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair Tcf25 PF04910.9 KEG14298.1 - 2e-64 217.8 0.0 3.3e-64 217.1 0.0 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Reo_sigmaC PF04582.7 KEG14299.1 - 4.3 6.4 25.6 0.32 10.1 0.5 5.2 2 2 4 6 6 6 0 Reovirus sigma C capsid protein DUF3713 PF12506.3 KEG14299.1 - 7.7 6.6 8.2 1.8 8.6 1.1 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3713) DUF137 PF02006.11 KEG14300.1 - 0.024 14.0 0.1 0.032 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF137 Cgr1 PF03879.9 KEG14300.1 - 1.1 9.4 6.6 0.65 10.2 3.3 1.5 1 1 0 1 1 1 0 Cgr1 family Ank_2 PF12796.2 KEG14301.1 - 4.4e-37 126.3 0.2 5.9e-23 81.0 0.0 3.3 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KEG14301.1 - 1.1e-33 113.3 2.5 3.4e-07 29.7 0.0 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 KEG14301.1 - 9.2e-32 108.8 0.7 2.7e-10 40.4 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEG14301.1 - 6.9e-31 103.2 0.0 4.8e-05 23.2 0.0 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 KEG14301.1 - 5.5e-22 77.2 3.4 1.3e-05 25.2 0.0 5.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) E1-E2_ATPase PF00122.15 KEG14302.1 - 1.7e-54 184.3 3.7 2.6e-53 180.4 2.0 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 KEG14302.1 - 3.1e-24 86.5 0.0 1.8e-23 84.0 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEG14302.1 - 9.6e-15 55.2 0.0 1.7e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KEG14302.1 - 1.5e-10 40.3 0.0 3.6e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KEG14302.1 - 0.00026 20.6 0.1 0.00091 18.8 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cwf_Cwc_15 PF04889.7 KEG14303.1 - 0.04 13.6 0.6 0.04 13.6 0.4 3.6 2 2 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein Ras PF00071.17 KEG14304.1 - 7.5e-24 83.9 0.0 1.2e-13 50.7 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KEG14304.1 - 4.5e-09 36.8 0.0 0.0001 22.7 0.0 3.1 2 1 0 2 2 2 2 Miro-like protein SCO1-SenC PF02630.9 KEG14305.1 - 7e-42 142.9 0.0 9.3e-42 142.5 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 KEG14305.1 - 0.001 18.7 0.0 0.0025 17.4 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 KEG14305.1 - 0.0019 18.2 0.0 0.0037 17.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like GRP PF07172.6 KEG14306.1 - 0.045 14.2 9.6 1 9.8 0.1 3.0 3 0 0 3 3 3 0 Glycine rich protein family YebO PF13974.1 KEG14307.1 - 0.14 11.9 0.1 0.25 11.1 0.1 1.4 1 0 0 1 1 1 0 YebO-like protein FBPase PF00316.15 KEG14308.1 - 6.7e-114 380.0 0.0 7.7e-114 379.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase DUF3733 PF12534.3 KEG14308.1 - 0.1 11.9 0.3 1 8.6 0.2 2.2 2 0 0 2 2 2 0 Leucine-rich repeat containing protein 8 Flg_bb_rod PF00460.15 KEG14308.1 - 0.48 10.2 2.6 0.62 9.8 0.2 2.3 2 0 0 2 2 2 0 Flagella basal body rod protein RRM_5 PF13893.1 KEG14309.1 - 3e-20 71.8 0.8 2.2e-10 40.2 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG14309.1 - 6e-13 48.5 0.1 4.9e-08 32.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEG14309.1 - 7e-11 41.6 0.0 6.5e-05 22.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC48_2 PF02933.12 KEG14309.1 - 0.0027 17.3 0.0 0.0051 16.4 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Calcipressin PF04847.7 KEG14309.1 - 0.014 15.0 0.6 0.042 13.4 0.2 1.9 2 0 0 2 2 2 0 Calcipressin DUF3588 PF12140.3 KEG14309.1 - 0.046 13.8 0.4 0.16 12.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3588) AsiA PF09010.5 KEG14309.1 - 0.12 12.2 0.5 0.4 10.5 0.1 2.1 2 1 0 2 2 2 0 Anti-Sigma Factor A RRM_3 PF08777.6 KEG14309.1 - 0.16 11.8 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif DUF1411 PF07199.6 KEG14309.1 - 0.25 10.7 2.4 2.9 7.2 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1411) DUF1269 PF06897.7 KEG14310.1 - 0.13 12.3 0.3 0.92 9.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) PolyA_pol PF01743.15 KEG14311.1 - 2.1e-25 89.3 0.0 4e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 KEG14311.1 - 3.5e-08 32.8 0.0 1e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A LRR_6 PF13516.1 KEG14312.1 - 1.6e-07 30.6 2.0 0.16 12.0 0.4 3.6 3 0 0 3 3 3 3 Leucine Rich repeat LRR_1 PF00560.28 KEG14312.1 - 0.0015 18.2 0.6 11 6.4 0.0 3.4 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_4 PF12799.2 KEG14312.1 - 0.0024 17.4 1.4 0.17 11.5 0.9 2.7 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG14312.1 - 0.004 16.8 0.3 0.21 11.3 0.2 2.5 1 1 1 2 2 2 2 Leucine rich repeat Tet_JBP PF12851.2 KEG14313.1 - 0.073 12.3 0.1 1.2 8.4 0.0 2.8 3 0 0 3 3 3 0 Oxygenase domain of the 2OGFeDO superfamily Actin PF00022.14 KEG14314.1 - 1.6e-147 491.0 0.0 1.8e-147 490.8 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 KEG14314.1 - 0.013 15.9 0.0 0.16 12.4 0.0 2.2 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF1504 PF07399.6 KEG14315.1 - 0.014 14.1 0.0 0.022 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1504) FlaC_arch PF05377.6 KEG14316.1 - 4.7 7.1 11.8 41 4.1 0.1 5.2 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) PCI_Csn8 PF10075.4 KEG14318.1 - 6.9e-10 38.8 0.0 9.8e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 KEG14318.1 - 5e-09 36.0 0.0 1.2e-08 34.7 0.0 1.6 1 1 1 2 2 2 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family GTP_EFTU PF00009.22 KEG14319.1 - 1.5e-27 96.2 0.0 2.5e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 KEG14319.1 - 1.5e-15 56.8 0.0 3.6e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 KEG14319.1 - 4.9e-09 35.8 0.0 9.8e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 KEG14319.1 - 4.3e-08 32.7 0.0 1e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV Miro PF08477.8 KEG14319.1 - 1.4e-06 28.8 0.0 2.4e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KEG14319.1 - 2.4e-05 24.2 0.0 5.3e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KEG14319.1 - 0.0024 17.7 0.1 1.4 8.7 0.0 2.3 1 1 1 2 2 2 2 Dynamin family GTP_EFTU_D2 PF03144.20 KEG14319.1 - 0.0038 17.3 0.0 0.012 15.6 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SRPRB PF09439.5 KEG14319.1 - 0.013 14.6 0.0 0.023 13.8 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Ras PF00071.17 KEG14319.1 - 0.044 13.1 0.0 0.08 12.3 0.0 1.4 1 0 0 1 1 1 0 Ras family Complex1_LYR PF05347.10 KEG14320.1 - 2.5e-12 46.4 2.0 2.8e-12 46.2 0.2 1.9 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KEG14320.1 - 2.4e-11 43.6 0.1 5.2e-11 42.5 0.1 1.6 1 0 0 1 1 1 1 Complex1_LYR-like IncA PF04156.9 KEG14322.1 - 0.0017 17.9 13.4 0.0017 17.9 9.3 3.4 1 1 1 2 2 2 1 IncA protein Myc-LZ PF02344.10 KEG14322.1 - 0.0039 16.7 3.4 0.0039 16.7 2.4 2.6 2 0 0 2 2 2 1 Myc leucine zipper domain DUF970 PF06153.6 KEG14322.1 - 0.037 13.9 1.3 0.52 10.2 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF970) Filament PF00038.16 KEG14322.1 - 2 7.8 45.6 0.16 11.4 14.4 2.4 1 1 1 2 2 2 0 Intermediate filament protein HrpF PF06266.7 KEG14322.1 - 2.6 8.2 8.3 0.81 9.8 0.7 3.1 2 0 0 2 2 2 0 HrpF protein FlgM PF04316.8 KEG14322.1 - 3.4 7.6 12.2 0.096 12.6 1.5 3.0 2 1 0 2 2 2 0 Anti-sigma-28 factor, FlgM V_ATPase_I PF01496.14 KEG14322.1 - 3.4 5.3 20.6 5.2 4.7 14.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 KEG14322.1 - 4.4 6.1 44.4 1.2 7.9 13.7 2.4 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DNA_pack_N PF02500.10 KEG14322.1 - 7.9 5.9 13.2 0.5 9.8 4.7 2.0 1 1 1 2 2 2 0 Probable DNA packing protein, N-terminus DEAD PF00270.24 KEG14324.1 - 7.7e-44 149.1 0.1 1.4e-43 148.3 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEG14324.1 - 2.7e-21 75.2 0.0 6.3e-21 74.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 KEG14324.1 - 5e-15 54.8 0.2 1.4e-14 53.3 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.10 KEG14324.1 - 0.0031 17.3 0.0 0.0081 16.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RNase_H2_suC PF08615.6 KEG14324.1 - 0.11 12.3 0.2 0.3 10.9 0.0 1.8 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Nucleoplasmin PF03066.10 KEG14324.1 - 1.8 8.0 13.2 0.1 12.1 2.4 2.5 2 0 0 2 2 2 0 Nucleoplasmin Sigma70_ner PF04546.8 KEG14324.1 - 3.7 7.1 17.7 3.1 7.3 3.9 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region Formyl_trans_N PF00551.14 KEG14325.1 - 3.4e-17 62.5 0.0 6.3e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase CS PF04969.11 KEG14326.1 - 1.6e-09 38.1 1.3 2.7e-09 37.4 0.9 1.4 1 0 0 1 1 1 1 CS domain Amino_oxidase PF01593.19 KEG14327.1 - 0.33 9.9 12.7 11 4.9 8.8 2.4 1 1 0 1 1 1 0 Flavin containing amine oxidoreductase TFIIA PF03153.8 KEG14327.1 - 1.8 8.3 24.7 2.9 7.6 17.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3248 PF11609.3 KEG14328.1 - 0.11 12.2 0.0 0.67 9.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3248) PAP2 PF01569.16 KEG14329.1 - 8.6e-19 67.4 1.4 8.6e-19 67.4 1.0 2.8 3 2 1 4 4 4 1 PAP2 superfamily DUF2534 PF10749.4 KEG14329.1 - 0.12 12.2 3.7 0.11 12.3 0.4 2.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2534) MCPsignal PF00015.16 KEG14330.1 - 0.0018 17.8 1.7 0.0034 16.9 1.2 1.4 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF2730 PF10805.3 KEG14330.1 - 0.033 13.9 0.0 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Herpes_capsid PF06112.6 KEG14330.1 - 0.17 11.9 2.7 0.21 11.6 0.9 1.8 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein MGC-24 PF05283.6 KEG14330.1 - 1.4 8.6 6.8 1.6 8.5 0.6 2.3 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) Actin PF00022.14 KEG14331.1 - 7.4e-121 403.2 0.0 8.5e-121 403.0 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KEG14331.1 - 0.00056 18.5 0.0 0.031 12.8 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein ERG4_ERG24 PF01222.12 KEG14333.1 - 5e-126 420.7 5.0 5.9e-126 420.4 3.5 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 KEG14333.1 - 5.3e-11 42.2 0.1 1.2e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 KEG14333.1 - 2.3e-07 30.8 1.8 3.8e-07 30.1 0.0 2.4 3 0 0 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.9 KEG14333.1 - 0.00011 22.3 0.5 0.00034 20.7 0.0 2.1 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Na_Ala_symp PF01235.12 KEG14333.1 - 0.015 13.8 4.2 0.031 12.8 2.9 1.5 1 0 0 1 1 1 0 Sodium:alanine symporter family EamA PF00892.15 KEG14334.1 - 5.4e-05 23.2 13.6 7.2e-05 22.8 9.4 1.2 1 0 0 1 1 1 1 EamA-like transporter family Chlorosome_CsmC PF11098.3 KEG14334.1 - 0.044 13.4 0.4 0.087 12.5 0.3 1.5 1 0 0 1 1 1 0 Chlorosome envelope protein C UPF0546 PF10639.4 KEG14334.1 - 0.13 12.1 1.7 0.21 11.3 1.2 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0546 Acyl-CoA_dh_C PF12806.2 KEG14334.1 - 0.22 11.3 2.1 0.61 9.9 1.3 1.8 1 1 1 2 2 2 0 Acetyl-CoA dehydrogenase C-terminal like TPT PF03151.11 KEG14334.1 - 0.66 9.6 7.3 0.5 9.9 3.5 1.7 1 1 0 1 1 1 0 Triose-phosphate Transporter family EmrE PF13536.1 KEG14334.1 - 1.5 9.0 15.7 0.13 12.4 3.9 2.1 1 1 1 2 2 2 0 Multidrug resistance efflux transporter NAD_binding_1 PF00175.16 KEG14335.1 - 3.6e-20 72.5 0.0 5.6e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KEG14335.1 - 1.3e-11 44.4 0.0 2.3e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Nsp1_C PF05064.8 KEG14336.1 - 3.4e-05 23.4 0.1 3.4e-05 23.4 0.1 1.8 2 0 0 2 2 2 1 Nsp1-like C-terminal region Imm29 PF15575.1 KEG14336.1 - 0.0069 16.0 1.9 0.045 13.3 0.9 2.0 1 1 1 2 2 2 1 Immunity protein 29 Prefoldin PF02996.12 KEG14336.1 - 0.019 14.6 1.0 0.076 12.6 0.1 2.0 2 0 0 2 2 2 0 Prefoldin subunit 7tm_6 PF02949.15 KEG14336.1 - 0.032 13.1 0.4 0.044 12.6 0.3 1.3 1 1 0 1 1 1 0 7tm Odorant receptor Snf7 PF03357.16 KEG14336.1 - 0.072 12.4 5.8 0.047 13.0 1.2 2.0 1 1 1 2 2 2 0 Snf7 UPF0564 PF10595.4 KEG14336.1 - 0.097 11.5 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 Fib_alpha PF08702.5 KEG14336.1 - 0.13 12.3 2.0 0.25 11.4 1.2 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family AATF-Che1 PF13339.1 KEG14336.1 - 0.29 11.2 2.6 2.6 8.2 0.3 2.1 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor ATG16 PF08614.6 KEG14336.1 - 0.77 9.5 6.3 0.98 9.2 1.2 2.5 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) HAUS-augmin3 PF14932.1 KEG14336.1 - 0.89 8.6 5.7 0.7 9.0 0.6 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Syntaxin PF00804.20 KEG14336.1 - 0.96 9.6 4.2 9.9 6.3 2.9 2.1 1 1 0 1 1 1 0 Syntaxin CENP-F_leu_zip PF10473.4 KEG14336.1 - 3.4 7.5 6.7 1.2 8.9 0.3 2.2 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fumerase PF05681.9 KEG14337.1 - 7.4e-86 287.5 0.0 9.3e-86 287.2 0.0 1.1 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Fumerase_C PF05683.7 KEG14337.1 - 7.7e-80 266.8 0.0 1.3e-79 266.0 0.0 1.4 1 0 0 1 1 1 1 Fumarase C-terminus LRR_6 PF13516.1 KEG14338.1 - 1.8e-17 61.3 0.0 0.78 10.0 0.1 8.0 8 0 0 8 8 8 5 Leucine Rich repeat LRR_4 PF12799.2 KEG14338.1 - 1.3e-14 53.4 0.0 0.0034 16.9 0.0 5.6 4 2 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 KEG14338.1 - 2.7e-12 44.7 0.7 0.31 11.4 0.0 8.2 9 0 0 9 9 9 2 Leucine rich repeat LRR_1 PF00560.28 KEG14338.1 - 3.1e-12 44.7 0.3 0.56 10.4 0.0 7.4 8 0 0 8 8 8 3 Leucine Rich Repeat LRR_8 PF13855.1 KEG14338.1 - 2.4e-08 33.5 0.7 0.32 10.7 0.2 5.3 4 3 0 4 4 4 2 Leucine rich repeat DUF4124 PF13511.1 KEG14339.1 - 0.065 13.2 0.0 0.073 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4124) Nop14 PF04147.7 KEG14341.1 - 0.046 11.6 3.0 0.078 10.8 2.0 1.3 1 0 0 1 1 1 0 Nop14-like family FANCL_C PF11793.3 KEG14341.1 - 0.048 13.6 2.9 0.17 11.8 2.0 2.0 1 0 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 KEG14341.1 - 0.3 11.1 5.9 1.1 9.4 4.1 2.1 1 0 0 1 1 1 0 RING-variant domain Ebola_NP PF05505.7 KEG14341.1 - 6.2 4.7 9.0 9.5 4.1 6.2 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein NIF PF03031.13 KEG14342.1 - 6.4e-30 103.9 0.0 8.3e-30 103.5 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase PF00702.21 KEG14342.1 - 0.018 15.4 0.0 0.29 11.4 0.0 2.3 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase DUF705 PF05152.7 KEG14342.1 - 0.051 12.5 0.0 0.074 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) HAD_2 PF13419.1 KEG14342.1 - 0.061 13.5 0.0 0.16 12.1 0.0 1.7 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase WD40 PF00400.27 KEG14343.1 - 2.3e-15 55.8 14.2 2e-09 36.9 0.2 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat CPSF_A PF03178.10 KEG14343.1 - 0.002 17.2 0.0 0.048 12.7 0.0 2.5 3 0 0 3 3 3 1 CPSF A subunit region DUF3312 PF11768.3 KEG14343.1 - 0.056 11.6 0.0 1.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) Metallophos PF00149.23 KEG14344.1 - 8e-19 67.8 0.1 1.7e-18 66.7 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Nucleoplasmin PF03066.10 KEG14344.1 - 0.38 10.2 2.4 1.2 8.6 0.1 2.3 2 1 0 2 2 2 0 Nucleoplasmin DEAD PF00270.24 KEG14345.1 - 9.3e-31 106.5 0.1 1.9e-30 105.5 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEG14345.1 - 4e-14 52.2 0.1 2e-08 33.9 0.1 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 KEG14345.1 - 0.0012 18.7 0.0 0.065 13.0 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KEG14345.1 - 0.0094 14.7 0.0 0.021 13.6 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain CAF1C_H4-bd PF12265.3 KEG14346.1 - 2.7e-12 46.4 0.2 5.8e-12 45.3 0.1 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.27 KEG14346.1 - 8.1e-12 44.5 15.4 0.0036 17.1 0.7 5.4 6 0 0 6 6 6 4 WD domain, G-beta repeat Pkinase PF00069.20 KEG14347.1 - 4e-42 144.1 0.0 9.1e-41 139.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain FHA PF00498.21 KEG14347.1 - 3.1e-16 59.2 0.1 5.6e-16 58.4 0.1 1.5 1 0 0 1 1 1 1 FHA domain Pkinase_Tyr PF07714.12 KEG14347.1 - 6.2e-16 58.2 0.0 8.8e-16 57.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 KEG14347.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL GOLGA2L5 PF15070.1 KEG14349.1 - 0.0096 14.4 2.9 0.0087 14.6 1.7 1.2 1 1 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 ADIP PF11559.3 KEG14349.1 - 0.01 15.7 3.5 0.086 12.7 0.2 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Kinesin-relat_1 PF12711.2 KEG14349.1 - 0.023 15.0 1.7 1.4 9.3 0.1 2.8 2 1 0 2 2 2 0 Kinesin motor DUF812 PF05667.6 KEG14349.1 - 0.043 12.3 2.3 0.053 12.0 1.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF972 PF06156.8 KEG14349.1 - 0.048 14.0 1.6 0.13 12.6 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Herpes_BLRF2 PF05812.7 KEG14349.1 - 0.058 13.2 0.2 0.075 12.8 0.1 1.4 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein TSC22 PF01166.13 KEG14349.1 - 0.061 13.3 2.0 1.4 8.9 0.1 2.3 2 1 0 2 2 2 0 TSC-22/dip/bun family Rnk_N PF14760.1 KEG14349.1 - 0.078 13.0 0.1 3.1 7.9 0.0 2.7 2 0 0 2 2 2 0 Rnk N-terminus Rootletin PF15035.1 KEG14349.1 - 0.092 12.7 9.8 2.7 7.9 4.4 2.3 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion NYD-SP28_assoc PF14775.1 KEG14349.1 - 0.11 12.1 3.3 1.3 8.7 0.2 2.7 2 1 1 3 3 3 0 Sperm tail C-terminal domain DIT1_PvcA PF05141.7 KEG14349.1 - 0.12 11.6 0.3 0.14 11.4 0.2 1.1 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein MAD PF05557.8 KEG14349.1 - 0.17 9.9 5.8 2.3 6.1 3.8 1.9 1 1 0 1 1 1 0 Mitotic checkpoint protein DUF724 PF05266.9 KEG14349.1 - 0.18 11.4 0.8 0.37 10.3 0.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF1192 PF06698.6 KEG14349.1 - 0.22 11.3 4.2 8.4 6.2 1.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Hemerythrin PF01814.18 KEG14349.1 - 0.23 11.6 4.2 0.14 12.3 1.0 1.8 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain NUDE_C PF04880.8 KEG14349.1 - 1.3 9.3 4.4 2.5 8.4 0.3 2.1 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region Cep57_CLD_2 PF14197.1 KEG14349.1 - 6.2 6.8 11.2 4.1 7.4 1.5 2.2 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 FUSC PF04632.7 KEG14349.1 - 8.5 4.6 8.1 11 4.3 5.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family TFIIS_C PF01096.13 KEG14350.1 - 9e-17 60.4 12.4 2e-16 59.3 8.6 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) TFIIS_M PF07500.9 KEG14350.1 - 2.5e-11 43.6 0.0 4.1e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain Baculo_LEF5_C PF11792.3 KEG14350.1 - 0.11 11.9 2.1 0.18 11.1 1.4 1.4 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain TFIIS_M PF07500.9 KEG14351.1 - 5.6e-08 32.8 0.0 9.5e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain DUF2752 PF10825.3 KEG14351.1 - 0.038 14.0 1.1 0.12 12.4 0.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) TFIIS_C PF01096.13 KEG14351.1 - 0.043 13.4 7.3 0.23 11.1 5.0 2.0 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS) HEAT_2 PF13646.1 KEG14352.1 - 2.9e-11 43.4 1.6 0.00014 22.0 0.0 4.1 4 0 0 4 4 4 3 HEAT repeats HEAT PF02985.17 KEG14352.1 - 9.3e-06 25.3 15.8 0.014 15.4 0.1 6.5 7 0 0 7 7 7 3 HEAT repeat Vac14_Fab1_bd PF12755.2 KEG14352.1 - 0.067 13.5 0.5 0.52 10.7 0.0 2.8 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region RNA_pol_Rpb1_5 PF04998.12 KEG14352.1 - 0.21 10.7 0.0 0.43 9.8 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Cnd1 PF12717.2 KEG14352.1 - 2.4 7.9 9.8 0.26 11.1 0.1 3.7 4 2 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 AAA PF00004.24 KEG14353.1 - 8.9e-32 110.0 0.0 6.3e-29 100.8 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KEG14353.1 - 7.2e-11 42.0 1.0 0.0029 17.2 0.0 4.4 3 1 0 3 3 3 2 NACHT domain AAA_16 PF13191.1 KEG14353.1 - 1.5e-10 41.3 6.7 0.00016 21.7 0.0 4.6 3 2 2 5 5 4 2 AAA ATPase domain AAA_22 PF13401.1 KEG14353.1 - 1.3e-08 34.9 0.2 0.00025 21.1 0.0 3.6 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KEG14353.1 - 8.3e-08 32.0 0.1 0.00022 20.9 0.0 3.4 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KEG14353.1 - 1.4e-07 31.5 0.1 0.0026 17.6 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KEG14353.1 - 2.1e-07 30.8 0.0 1.2e-05 25.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KEG14353.1 - 1.8e-06 28.7 0.0 0.0079 17.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 KEG14353.1 - 2e-06 27.5 0.0 0.00056 19.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KEG14353.1 - 2.1e-06 27.1 0.0 0.026 14.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain IstB_IS21 PF01695.12 KEG14353.1 - 2.3e-06 27.1 0.1 0.00012 21.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_19 PF13245.1 KEG14353.1 - 6.9e-06 25.7 0.1 0.04 13.6 0.0 3.4 2 0 0 2 2 2 2 Part of AAA domain AAA_25 PF13481.1 KEG14353.1 - 2.4e-05 23.8 0.3 0.03 13.7 0.1 2.8 2 1 1 3 3 3 1 AAA domain Arch_ATPase PF01637.13 KEG14353.1 - 9.5e-05 22.1 0.0 0.68 9.5 0.0 3.5 3 1 1 4 4 4 1 Archaeal ATPase AAA_28 PF13521.1 KEG14353.1 - 0.00021 21.3 0.3 1.2 9.1 0.0 3.5 4 0 0 4 4 4 2 AAA domain T2SE PF00437.15 KEG14353.1 - 0.00022 20.2 0.0 0.5 9.2 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein ABC_tran PF00005.22 KEG14353.1 - 0.00031 21.0 0.3 1.9 8.7 0.0 3.0 3 0 0 3 3 3 2 ABC transporter AAA_10 PF12846.2 KEG14353.1 - 0.00048 19.6 0.0 0.15 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA-like domain AAA_18 PF13238.1 KEG14353.1 - 0.00072 19.8 0.0 0.42 10.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 KEG14353.1 - 0.00081 18.2 0.0 0.0013 17.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus NB-ARC PF00931.17 KEG14353.1 - 0.0017 17.3 1.9 3.3 6.4 0.0 4.0 4 1 1 5 5 5 0 NB-ARC domain RNA_helicase PF00910.17 KEG14353.1 - 0.0021 18.1 0.0 0.25 11.5 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Sigma54_activat PF00158.21 KEG14353.1 - 0.0022 17.5 0.0 0.13 11.7 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 KEG14353.1 - 0.0022 17.2 1.1 0.11 11.6 0.2 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ATP_bind_1 PF03029.12 KEG14353.1 - 0.0029 17.1 0.3 0.21 11.1 0.0 3.0 4 0 0 4 4 3 1 Conserved hypothetical ATP binding protein PhoH PF02562.11 KEG14353.1 - 0.0031 16.7 0.2 0.05 12.8 0.1 2.2 2 0 0 2 2 2 1 PhoH-like protein CobU PF02283.11 KEG14353.1 - 0.0041 16.5 0.0 0.095 12.1 0.0 2.6 3 0 0 3 3 2 1 Cobinamide kinase / cobinamide phosphate guanyltransferase Zeta_toxin PF06414.7 KEG14353.1 - 0.0073 15.4 0.1 1.8 7.5 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin AAA_23 PF13476.1 KEG14353.1 - 0.013 15.7 0.0 2.5 8.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.15 KEG14353.1 - 0.021 13.5 0.0 2 7.0 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit Sigma54_activ_2 PF14532.1 KEG14353.1 - 0.027 14.5 0.4 1.4 8.9 0.0 2.8 3 0 0 3 3 2 0 Sigma-54 interaction domain DUF815 PF05673.8 KEG14353.1 - 0.027 13.3 0.0 1.7 7.4 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.13 KEG14353.1 - 0.028 13.8 0.1 5.2 6.4 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF258 PF03193.11 KEG14353.1 - 0.038 13.1 0.0 2.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Guanylate_kin PF00625.16 KEG14353.1 - 0.042 13.2 0.0 0.25 10.7 0.0 2.1 2 0 0 2 2 2 0 Guanylate kinase RNA12 PF10443.4 KEG14353.1 - 0.048 12.1 0.0 0.17 10.3 0.0 1.7 2 0 0 2 2 2 0 RNA12 protein AAA_24 PF13479.1 KEG14353.1 - 0.062 12.8 0.0 2.5 7.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 KEG14353.1 - 0.065 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SRP54 PF00448.17 KEG14353.1 - 0.088 12.2 0.0 2.9 7.2 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain KaiC PF06745.8 KEG14353.1 - 0.088 11.9 0.0 5.5 6.0 0.0 2.3 2 0 0 2 2 2 0 KaiC Viral_helicase1 PF01443.13 KEG14353.1 - 0.089 12.2 0.0 5.5 6.4 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_PrkA PF08298.6 KEG14353.1 - 0.09 11.4 0.0 2 6.9 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain NTPase_1 PF03266.10 KEG14353.1 - 0.099 12.3 0.0 2.9 7.5 0.0 2.5 2 0 0 2 2 2 0 NTPase MobB PF03205.9 KEG14353.1 - 0.14 11.8 0.0 14 5.3 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 KEG14353.1 - 0.17 11.5 0.1 1.8 8.1 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 KEG14353.1 - 0.18 11.3 0.1 9.9 5.6 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Phosducin PF02114.11 KEG14354.1 - 7.2e-07 28.1 0.1 1.4e-06 27.2 0.0 1.3 1 1 0 1 1 1 1 Phosducin DUF4196 PF13846.1 KEG14354.1 - 0.18 12.0 1.2 0.22 11.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4196) ATAD4 PF15321.1 KEG14355.1 - 0.022 15.7 0.1 0.053 14.5 0.1 1.6 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 PEX11 PF05648.9 KEG14356.1 - 1e-06 28.2 1.5 0.012 14.8 0.1 2.1 1 1 1 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) Ank_2 PF12796.2 KEG14357.1 - 3.2e-54 181.2 13.8 2.1e-16 60.0 0.2 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KEG14357.1 - 4.6e-45 149.2 5.8 9.5e-10 37.7 0.1 7.3 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 KEG14357.1 - 6e-37 125.3 7.2 4.6e-09 36.5 0.1 5.2 2 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEG14357.1 - 1.5e-34 114.5 5.4 0.00014 21.7 0.0 8.0 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.1 KEG14357.1 - 2.5e-34 116.5 4.1 4.7e-10 39.3 0.0 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) TPR_11 PF13414.1 KEG14357.1 - 1.2e-16 60.0 4.3 9.6e-11 41.1 1.9 2.6 1 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KEG14357.1 - 5.3e-07 29.0 5.1 0.0014 18.3 0.0 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KEG14357.1 - 6e-07 28.8 3.3 4.2e-05 22.9 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 KEG14357.1 - 2.1e-05 24.3 0.9 0.098 12.9 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 KEG14357.1 - 0.0013 18.5 0.1 0.0039 17.0 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 KEG14357.1 - 0.0016 18.9 0.5 0.098 13.3 0.0 3.3 1 1 1 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 KEG14357.1 - 0.0048 16.9 1.2 0.017 15.2 0.9 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 KEG14357.1 - 0.054 14.1 2.5 0.74 10.5 0.6 3.0 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 KEG14357.1 - 0.14 12.0 1.4 0.88 9.5 0.0 3.0 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 KEG14357.1 - 0.48 10.7 2.8 1.2 9.4 0.0 2.8 3 1 0 3 3 3 0 Tetratricopeptide repeat WD40 PF00400.27 KEG14358.1 - 5.2e-10 38.8 14.3 5.9e-05 22.7 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat PARP_regulatory PF01358.13 KEG14359.1 - 9.3e-18 63.8 0.0 1.4e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Poly A polymerase regulatory subunit Lig_chan-Glu_bd PF10613.4 KEG14359.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Ligated ion channel L-glutamate- and glycine-binding site Cytadhesin_P30 PF07271.6 KEG14360.1 - 2 7.6 4.5 4.5 6.4 0.9 2.3 2 0 0 2 2 2 0 Cytadhesin P30/P32 Phage_GPO PF05929.6 KEG14362.1 - 0.028 13.6 0.8 0.04 13.1 0.6 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase gag_pre-integrs PF13976.1 KEG14362.1 - 0.2 11.3 1.0 0.47 10.1 0.1 2.1 2 0 0 2 2 2 0 GAG-pre-integrase domain Spectrin PF00435.16 KEG14362.1 - 0.21 11.8 10.3 1.3 9.2 5.1 2.5 2 1 0 2 2 2 0 Spectrin repeat DUF3232 PF11554.3 KEG14362.1 - 0.25 11.2 1.4 0.41 10.5 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3232) zf-Tim10_DDP PF02953.10 KEG14363.1 - 0.092 12.0 1.1 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 Tim10/DDP family zinc finger Pkinase PF00069.20 KEG14364.1 - 4.5e-38 130.9 0.0 1.4e-37 129.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG14364.1 - 1.9e-27 95.9 0.0 1.2e-19 70.3 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KEG14364.1 - 0.00028 20.7 3.5 0.00099 18.9 0.3 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KEG14364.1 - 0.029 13.3 0.0 0.055 12.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 KEG14364.1 - 0.049 12.6 0.0 0.094 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Rhodanese PF00581.15 KEG14365.1 - 6.3e-14 52.2 0.0 1.6e-05 25.2 0.0 3.3 2 1 0 2 2 2 2 Rhodanese-like domain AAA_16 PF13191.1 KEG14367.1 - 4.3e-07 30.1 0.2 1.6e-06 28.2 0.1 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KEG14367.1 - 0.00069 19.7 0.0 0.0018 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KEG14367.1 - 0.004 16.0 0.2 0.016 14.0 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain Zeta_toxin PF06414.7 KEG14367.1 - 0.013 14.6 0.0 0.027 13.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin cobW PF02492.14 KEG14367.1 - 0.037 13.4 0.0 0.097 12.1 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 KEG14367.1 - 0.043 13.5 0.0 0.13 11.9 0.0 1.8 1 0 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 KEG14367.1 - 0.044 14.0 0.0 0.2 11.9 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Amastin PF07344.6 KEG14368.1 - 1.5e-51 174.0 15.9 1.7e-51 173.8 11.0 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 KEG14368.1 - 6.7e-05 22.6 16.5 8.1e-05 22.3 11.1 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF3278 PF11683.3 KEG14368.1 - 0.23 11.4 3.3 0.7 9.8 0.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3278) DUF2456 PF10445.4 KEG14368.1 - 0.25 11.2 6.9 1.1 9.1 4.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2456) ABC_membrane PF00664.18 KEG14369.1 - 2.9e-104 348.3 27.2 4.5e-57 193.5 8.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KEG14369.1 - 6.9e-67 223.9 0.0 1.5e-33 115.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KEG14369.1 - 9.5e-15 54.4 0.1 2.1e-06 27.1 0.0 3.7 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 KEG14369.1 - 4e-07 29.3 0.0 0.028 13.6 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_21 PF13304.1 KEG14369.1 - 4.8e-07 30.0 0.0 0.18 11.7 0.0 3.9 3 1 1 4 4 4 2 AAA domain AAA_17 PF13207.1 KEG14369.1 - 4.4e-06 27.5 0.0 0.045 14.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 KEG14369.1 - 6.1e-06 25.0 0.0 0.019 13.5 0.0 2.2 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 KEG14369.1 - 8.8e-06 25.1 0.4 0.12 11.9 0.0 3.0 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 KEG14369.1 - 3.5e-05 23.9 2.5 0.26 11.4 0.1 4.0 2 2 0 2 2 2 2 AAA domain AAA PF00004.24 KEG14369.1 - 4.7e-05 23.5 0.1 0.42 10.8 0.0 3.6 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KEG14369.1 - 5.9e-05 22.5 0.5 1.6 8.0 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.1 KEG14369.1 - 0.00011 22.2 2.1 0.74 9.7 0.7 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 KEG14369.1 - 0.0002 21.1 0.1 0.05 13.3 0.0 3.5 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.20 KEG14369.1 - 0.00044 19.8 0.5 0.73 9.2 0.0 2.7 2 1 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.1 KEG14369.1 - 0.00052 20.3 0.1 0.054 13.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KEG14369.1 - 0.0027 16.8 0.0 0.17 10.9 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_28 PF13521.1 KEG14369.1 - 0.0044 16.9 0.0 1.3 8.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 KEG14369.1 - 0.0079 15.7 0.0 0.67 9.4 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.8 KEG14369.1 - 0.0095 14.8 0.0 1.9 7.3 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 KEG14369.1 - 0.012 15.5 0.0 0.62 9.9 0.0 3.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KEG14369.1 - 0.016 15.5 0.0 7 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KEG14369.1 - 0.017 15.3 0.0 3.7 7.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase SbcCD_C PF13558.1 KEG14369.1 - 0.019 14.8 7.7 1.3 8.9 0.2 4.3 3 2 0 3 3 3 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.10 KEG14369.1 - 0.02 13.5 0.0 2.1 6.9 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Miro PF08477.8 KEG14369.1 - 0.032 14.7 0.0 9.1 6.8 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein MMR_HSR1 PF01926.18 KEG14369.1 - 0.038 13.9 0.0 3.2 7.7 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase G-alpha PF00503.15 KEG14369.1 - 0.047 12.3 0.0 2.9 6.4 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit LHC PF00556.15 KEG14369.1 - 2.4 8.0 5.3 17 5.3 0.7 3.4 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit Myosin_head PF00063.16 KEG14370.1 - 1.1e-220 734.2 0.0 1.5e-220 733.8 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 KEG14370.1 - 4.7e-18 65.2 0.0 6.7e-10 38.6 0.0 3.2 2 1 0 2 2 2 2 Myosin tail WW PF00397.21 KEG14370.1 - 1.9e-07 30.8 1.1 4.5e-07 29.5 0.8 1.6 1 0 0 1 1 1 1 WW domain FYVE PF01363.16 KEG14370.1 - 0.00017 21.3 12.6 0.00037 20.3 8.7 1.5 1 0 0 1 1 1 1 FYVE zinc finger AAA_22 PF13401.1 KEG14370.1 - 0.0087 16.2 0.0 0.042 14.0 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEG14370.1 - 0.037 14.0 1.9 0.19 11.7 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 KEG14370.1 - 0.048 14.4 1.3 0.25 12.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.22 KEG14370.1 - 0.067 13.4 0.0 0.25 11.6 0.0 1.9 1 0 0 1 1 1 0 ABC transporter Asp-B-Hydro_N PF05279.6 KEG14370.1 - 9.5 5.9 13.6 17 5.1 9.4 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DASH_Dad2 PF08654.5 KEG14371.1 - 0.0069 16.3 0.4 0.027 14.4 0.1 2.2 2 0 0 2 2 2 1 DASH complex subunit Dad2 Microtub_assoc PF07989.6 KEG14371.1 - 0.013 15.3 2.0 0.029 14.1 0.1 2.6 2 2 0 2 2 2 0 Microtubule associated MbeD_MobD PF04899.7 KEG14371.1 - 0.034 14.0 8.1 4.3 7.3 5.6 3.2 1 1 0 1 1 1 0 MbeD/MobD like DUF4515 PF14988.1 KEG14371.1 - 0.065 12.8 13.1 0.52 9.9 0.2 3.8 3 1 0 4 4 4 0 Domain of unknown function (DUF4515) DUF4201 PF13870.1 KEG14371.1 - 0.31 10.4 9.1 2 7.8 1.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) OmpH PF03938.9 KEG14371.1 - 0.34 10.8 5.7 1.3 8.9 2.0 2.7 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Mod_r PF07200.8 KEG14371.1 - 0.42 10.5 11.0 2.2 8.2 0.7 3.3 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein SlyX PF04102.7 KEG14371.1 - 0.65 10.4 14.2 0.7 10.2 1.1 3.7 3 1 1 4 4 4 0 SlyX DUF3972 PF13118.1 KEG14371.1 - 1.2 9.2 7.6 1.2 9.1 0.2 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF3972) ERM PF00769.14 KEG14371.1 - 1.7 8.0 13.5 2.5 7.5 7.0 2.6 2 1 0 2 2 2 0 Ezrin/radixin/moesin family DUF641 PF04859.7 KEG14371.1 - 4.5 7.0 10.6 1 9.1 0.8 3.0 2 1 0 3 3 3 0 Plant protein of unknown function (DUF641) GAS PF13851.1 KEG14371.1 - 4.7 6.3 13.0 0.56 9.3 0.5 2.9 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DivIC PF04977.10 KEG14371.1 - 4.9 6.7 11.0 13 5.3 0.0 4.1 4 0 0 4 4 4 0 Septum formation initiator ADIP PF11559.3 KEG14371.1 - 5.9 6.7 11.1 6.6 6.6 0.2 2.6 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding HEAT_2 PF13646.1 KEG14372.1 - 3.7e-05 23.9 4.8 0.58 10.4 0.4 3.8 2 2 1 3 3 3 2 HEAT repeats CDC14 PF08045.6 KEG14372.1 - 0.00012 21.2 0.0 0.00016 20.9 0.0 1.1 1 0 0 1 1 1 1 Cell division control protein 14, SIN component HEAT PF02985.17 KEG14372.1 - 0.00029 20.6 0.6 0.072 13.2 0.0 3.5 3 0 0 3 3 3 1 HEAT repeat Dynactin PF12455.3 KEG14372.1 - 0.0088 14.9 0.9 0.013 14.4 0.6 1.2 1 0 0 1 1 1 1 Dynein associated protein tRNA-synt_His PF13393.1 KEG14372.1 - 0.0093 15.0 0.1 3.6 6.5 0.0 2.3 2 0 0 2 2 2 2 Histidyl-tRNA synthetase Fes1 PF08609.5 KEG14372.1 - 0.02 15.3 1.4 0.027 14.9 0.2 1.8 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 KIP1 PF07765.7 KEG14372.1 - 0.071 12.9 1.1 0.73 9.7 0.0 2.8 3 0 0 3 3 3 0 KIP1-like protein Arm PF00514.18 KEG14372.1 - 1.1 9.2 3.6 11 5.9 0.0 3.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 KEG14372.1 - 2.7 8.6 5.2 49 4.5 0.0 3.5 3 1 0 3 3 3 0 HEAT-like repeat PBP1_TM PF14812.1 KEG14373.1 - 0.0042 17.3 4.2 0.0082 16.4 2.9 1.4 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Sporozoite_P67 PF05642.6 KEG14373.1 - 0.25 9.1 0.7 0.36 8.6 0.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen N2227 PF07942.7 KEG14374.1 - 4.5e-93 311.1 0.0 6.2e-93 310.6 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 KEG14374.1 - 0.074 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Mito_fiss_reg PF05308.6 KEG14374.1 - 8.2 5.7 12.1 15 4.8 8.4 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator EF-hand_7 PF13499.1 KEG14376.1 - 4.5e-14 52.3 0.2 9.2e-12 44.9 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KEG14376.1 - 6.2e-10 37.6 0.3 0.00049 19.2 0.1 3.5 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 KEG14376.1 - 7.5e-10 38.2 0.1 1.4e-08 34.1 0.1 2.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 KEG14376.1 - 1.2e-07 30.9 5.1 0.058 13.3 0.3 4.2 3 1 2 5 5 5 2 EF-hand domain EF-hand_9 PF14658.1 KEG14376.1 - 7.4e-05 22.5 0.0 0.00021 21.1 0.0 1.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 KEG14376.1 - 0.016 14.5 1.1 0.016 14.5 0.8 2.7 3 1 1 4 4 4 0 EF hand UPRTase PF14681.1 KEG14377.1 - 9.5e-72 240.5 0.0 1.2e-71 240.1 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KEG14377.1 - 3.9e-06 26.5 0.0 6.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain TPR_11 PF13414.1 KEG14378.1 - 1.7e-15 56.4 0.3 1.7e-09 37.1 0.1 3.7 2 1 1 3 3 3 3 TPR repeat SET PF00856.23 KEG14378.1 - 3e-09 37.3 0.0 4.7e-07 30.2 0.0 2.5 2 0 0 2 2 2 1 SET domain TPR_12 PF13424.1 KEG14378.1 - 0.00097 19.0 0.4 0.37 10.7 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEG14378.1 - 0.0044 16.5 1.6 0.31 10.7 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEG14378.1 - 0.037 13.9 0.9 1.4 8.9 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_M41 PF01434.13 KEG14379.1 - 1.1e-43 149.1 0.1 1.6e-43 148.6 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KEG14379.1 - 5.3e-39 133.4 0.0 9.5e-39 132.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KEG14379.1 - 0.00051 19.1 0.0 0.0015 17.6 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KEG14379.1 - 0.00051 19.7 0.0 0.0023 17.6 0.0 2.2 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 KEG14379.1 - 0.00062 19.2 0.1 1 8.7 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_22 PF13401.1 KEG14379.1 - 0.001 19.2 0.0 0.057 13.5 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEG14379.1 - 0.0014 19.3 0.0 0.0038 18.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KEG14379.1 - 0.0019 18.1 0.0 0.014 15.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KEG14379.1 - 0.0056 16.6 0.1 0.056 13.4 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.12 KEG14379.1 - 0.0073 15.7 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 KEG14379.1 - 0.0078 14.9 0.0 0.013 14.2 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_14 PF13173.1 KEG14379.1 - 0.013 15.3 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KEG14379.1 - 0.027 13.6 0.0 0.12 11.5 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KEG14379.1 - 0.028 14.1 0.2 0.15 11.7 0.1 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) CPSF_A PF03178.10 KEG14382.1 - 1.4e-46 159.0 0.0 2.4e-46 158.2 0.0 1.4 1 0 0 1 1 1 1 CPSF A subunit region Pkinase PF00069.20 KEG14383.1 - 2.2e-69 233.5 0.0 3.3e-69 232.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG14383.1 - 2.3e-35 121.9 0.0 3.4e-35 121.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG14383.1 - 3.3e-08 32.8 0.0 5.7e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEG14383.1 - 0.037 13.7 0.0 0.08 12.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KEG14383.1 - 0.068 11.9 1.8 0.16 10.7 1.2 1.5 1 1 0 1 1 1 0 Seadornavirus VP7 POLO_box PF00659.13 KEG14383.1 - 0.12 12.3 0.0 1.6 8.7 0.0 2.9 2 0 0 2 2 2 0 POLO box duplicated region Kdo PF06293.9 KEG14383.1 - 0.15 11.1 0.0 0.28 10.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family OAD_beta PF03977.8 KEG14384.1 - 0.16 10.6 0.6 0.17 10.5 0.4 1.0 1 0 0 1 1 1 0 Na+-transporting oxaloacetate decarboxylase beta subunit DUF3742 PF12553.3 KEG14384.1 - 0.21 12.0 1.4 2.1 8.8 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) DUF3808 PF10300.4 KEG14386.1 - 1e-25 90.2 1.9 2e-25 89.3 1.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_12 PF13424.1 KEG14386.1 - 7.7e-11 41.7 9.1 5.1e-05 23.1 0.0 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 KEG14386.1 - 1.2e-05 25.3 4.9 0.017 15.2 0.0 3.9 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 KEG14386.1 - 5.5e-05 22.7 14.6 0.17 11.9 0.0 6.4 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_15 PF13429.1 KEG14386.1 - 0.0002 20.5 0.8 0.00067 18.8 0.5 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEG14386.1 - 0.00056 20.5 8.1 4.5 8.0 0.1 4.7 6 1 0 6 6 4 2 Tetratricopeptide repeat DUF2225 PF09986.4 KEG14386.1 - 0.00063 19.2 3.3 0.035 13.5 0.2 3.0 3 0 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_11 PF13414.1 KEG14386.1 - 0.0031 17.1 14.5 0.12 12.0 0.2 5.0 6 0 0 6 6 6 2 TPR repeat Egg_lysin PF01303.12 KEG14386.1 - 0.008 16.1 0.0 0.025 14.5 0.0 1.9 1 0 0 1 1 1 1 Egg lysin (Sperm-lysin) TPR_19 PF14559.1 KEG14386.1 - 0.012 15.9 5.8 0.27 11.6 0.1 5.0 4 2 1 6 6 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEG14386.1 - 0.025 15.0 9.5 3.3 8.3 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 KEG14386.1 - 0.026 14.3 2.9 27 4.8 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 KEG14386.1 - 0.046 13.3 6.4 7.7 6.3 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Striatin PF08232.7 KEG14387.1 - 0.014 15.7 2.5 0.014 15.7 1.7 4.5 3 1 2 5 5 5 0 Striatin family DUF1515 PF07439.6 KEG14387.1 - 0.017 14.9 5.5 5.5 6.8 0.0 3.8 3 1 2 5 5 5 0 Protein of unknown function (DUF1515) CesA PF11439.3 KEG14387.1 - 0.048 13.5 9.9 0.45 10.4 1.0 3.9 3 1 0 3 3 3 0 Type III secretion system filament chaperone CesA Birna_VP5 PF03042.9 KEG14387.1 - 0.059 12.8 2.1 0.08 12.4 0.0 2.1 2 0 0 2 2 2 0 Birnavirus VP5 protein WD40_alt PF14077.1 KEG14387.1 - 4.3 7.0 6.6 18 5.0 0.7 3.5 3 0 0 3 3 3 0 Alternative WD40 repeat motif DUF1664 PF07889.7 KEG14387.1 - 7.1 6.4 19.5 2.2 8.1 2.6 4.3 4 1 0 4 4 4 0 Protein of unknown function (DUF1664) SnoaL_2 PF12680.2 KEG14388.1 - 0.0047 17.3 0.4 0.016 15.5 0.2 2.0 1 1 0 1 1 1 1 SnoaL-like domain ATP-synt_C PF00137.16 KEG14389.1 - 2e-26 91.6 40.5 4.1e-15 55.4 8.5 2.6 3 0 0 3 3 3 2 ATP synthase subunit C Ribosomal_L15e PF00827.12 KEG14390.1 - 1.7e-87 291.8 10.7 2e-87 291.7 7.4 1.0 1 0 0 1 1 1 1 Ribosomal L15 Ribosomal_L18p PF00861.17 KEG14391.1 - 4e-45 152.8 10.2 5.7e-37 126.5 0.3 3.0 3 0 0 3 3 3 2 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 KEG14391.1 - 8.2e-24 84.0 4.2 1.9e-23 82.8 2.9 1.6 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region DivIC PF04977.10 KEG14392.1 - 0.014 14.9 0.2 0.024 14.0 0.1 1.3 1 0 0 1 1 1 0 Septum formation initiator EMP24_GP25L PF01105.19 KEG14393.1 - 2.4e-43 148.0 0.0 2.8e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD 7TM_GPCR_Srsx PF10320.4 KEG14394.1 - 0.039 13.1 0.3 0.045 12.9 0.2 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Acyl_transf_3 PF01757.17 KEG14394.1 - 0.092 11.5 2.5 0.11 11.2 1.7 1.1 1 0 0 1 1 1 0 Acyltransferase family DUF4234 PF14018.1 KEG14394.1 - 0.98 9.2 3.6 1.2 8.9 1.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4234) Lysine_decarbox PF03641.9 KEG14395.1 - 0.031 14.0 0.0 0.09 12.5 0.0 1.8 1 0 0 1 1 1 0 Possible lysine decarboxylase Ebp2 PF05890.7 KEG14396.1 - 5.3e-47 160.3 17.6 8.2e-47 159.7 12.0 1.5 1 1 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 DUF3840 PF12944.2 KEG14396.1 - 0.016 15.0 0.5 0.033 14.0 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3840) GAS PF13851.1 KEG14397.1 - 1.2e-62 210.6 22.4 1.2e-62 210.6 15.5 2.5 2 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding DTW PF03942.10 KEG14398.1 - 1.4e-26 93.0 0.0 2e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 DTW domain zf-B_box PF00643.19 KEG14398.1 - 0.069 13.0 0.7 0.12 12.2 0.5 1.4 1 0 0 1 1 1 0 B-box zinc finger zf-RING_3 PF14369.1 KEG14398.1 - 0.13 12.2 4.8 0.2 11.6 0.2 2.5 2 0 0 2 2 2 0 zinc-finger DNA_pol_E_B PF04042.11 KEG14399.1 - 7.1e-28 97.2 0.1 1.2e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B EF-hand_like PF09279.6 KEG14402.1 - 0.047 13.7 1.5 0.089 12.8 1.1 1.5 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like DUF4094 PF13334.1 KEG14402.1 - 0.097 13.0 0.3 0.097 13.0 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) CorA PF01544.13 KEG14402.1 - 0.13 11.2 2.5 0.16 10.9 1.7 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein APG6 PF04111.7 KEG14402.1 - 0.15 11.0 10.1 0.21 10.5 7.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Peptidase_C6 PF00851.13 KEG14402.1 - 0.42 9.1 6.5 0.5 8.9 4.5 1.1 1 0 0 1 1 1 0 Helper component proteinase CENP-H PF05837.7 KEG14402.1 - 0.9 9.7 17.2 0.66 10.1 4.1 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Proteasom_Rpn13 PF04683.8 KEG14403.1 - 7.6e-19 67.5 0.1 1.1e-18 67.0 0.1 1.2 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor FlgD_ig PF13860.1 KEG14403.1 - 0.048 13.4 0.0 0.48 10.1 0.0 2.1 2 0 0 2 2 2 0 FlgD Ig-like domain cNMP_binding PF00027.24 KEG14406.1 - 1.8e-17 62.9 0.0 3.5e-09 36.3 0.0 3.6 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain YpjP PF14005.1 KEG14407.1 - 0.0069 16.1 5.8 0.014 15.1 1.1 2.1 1 1 1 2 2 2 1 YpjP-like protein DUF3091 PF11291.3 KEG14407.1 - 0.028 14.3 0.8 0.15 12.0 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3091) 3-alpha PF03475.9 KEG14407.1 - 0.066 12.9 0.9 0.45 10.2 0.0 2.5 2 0 0 2 2 2 0 3-alpha domain BCAS3 PF12490.3 KEG14407.1 - 0.11 11.7 2.4 0.14 11.4 1.7 1.3 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 DUF3818 PF12825.2 KEG14407.1 - 1.6 7.3 5.9 1.8 7.1 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) SseB PF07179.7 KEG14408.1 - 1.7e-06 27.8 0.0 0.002 17.9 0.0 2.4 2 0 0 2 2 2 2 SseB protein N-terminal domain SR-25 PF10500.4 KEG14408.1 - 6.2 6.2 14.8 0.33 10.3 3.1 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein ADH_N PF08240.7 KEG14409.1 - 3.8e-14 52.3 1.3 2.2e-13 49.9 0.2 2.4 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KEG14409.1 - 1.2e-12 48.7 0.2 4e-12 47.1 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KEG14409.1 - 3e-12 46.2 0.2 5.4e-12 45.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF4147 PF13660.1 KEG14409.1 - 0.084 11.9 0.8 0.24 10.4 0.0 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4147) HALZ PF02183.13 KEG14411.1 - 0.003 17.2 8.2 0.0069 16.0 0.1 3.3 2 1 1 3 3 3 1 Homeobox associated leucine zipper DUF4200 PF13863.1 KEG14411.1 - 0.0081 16.1 8.2 0.0081 16.1 5.7 4.1 3 1 1 4 4 4 1 Domain of unknown function (DUF4200) Atg14 PF10186.4 KEG14411.1 - 0.017 14.0 16.6 0.17 10.8 3.4 2.4 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 bZIP_1 PF00170.16 KEG14411.1 - 0.052 13.5 12.2 0.14 12.1 0.1 4.4 2 1 1 3 3 3 0 bZIP transcription factor BioW PF03744.8 KEG14411.1 - 0.12 11.7 5.0 0.025 13.9 0.7 1.8 2 0 0 2 2 2 0 6-carboxyhexanoate--CoA ligase IncA PF04156.9 KEG14411.1 - 0.14 11.7 29.3 0.2 11.2 3.7 3.4 3 0 0 3 3 3 0 IncA protein DUF948 PF06103.6 KEG14411.1 - 0.73 9.7 7.9 0.51 10.2 0.2 3.5 2 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Reo_sigmaC PF04582.7 KEG14411.1 - 0.91 8.6 10.6 2.8 7.0 1.2 2.5 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Phage_GPO PF05929.6 KEG14411.1 - 1.6 7.9 17.1 0.38 9.9 1.4 3.3 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase TerB-C PF15615.1 KEG14411.1 - 1.8 8.8 14.7 6.3 7.0 1.3 2.7 2 0 0 2 2 2 0 TerB-C domain DUF2730 PF10805.3 KEG14411.1 - 2.2 8.0 10.2 2.2 8.0 0.5 4.3 2 2 1 3 3 3 0 Protein of unknown function (DUF2730) TINF2_N PF14973.1 KEG14411.1 - 2.7 8.1 9.2 1.2 9.2 2.3 2.5 2 1 0 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus APG6 PF04111.7 KEG14411.1 - 9.7 5.1 25.8 0.04 12.9 5.8 2.7 3 0 0 3 3 3 0 Autophagy protein Apg6 UvsW PF11637.3 KEG14412.1 - 0.018 14.7 0.3 4 7.2 0.1 2.8 2 0 0 2 2 2 0 ATP-dependant DNA helicase UvsW Baculo_p24 PF05073.7 KEG14412.1 - 0.28 10.7 0.6 0.61 9.6 0.4 1.5 1 0 0 1 1 1 0 Baculovirus P24 capsid protein Kinesin PF00225.18 KEG14414.1 - 9.3e-87 290.8 1.2 2.9e-86 289.2 0.0 2.6 2 0 0 2 2 2 1 Kinesin motor domain Peptidase_U57 PF05582.7 KEG14414.1 - 0.022 13.7 0.2 0.022 13.7 0.1 5.9 3 3 3 6 6 6 0 YabG peptidase U57 FGE-sulfatase PF03781.11 KEG14416.1 - 2.5e-19 69.6 1.3 5e-19 68.6 0.9 1.5 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Methyltransf_25 PF13649.1 KEG14416.1 - 2.3e-13 50.3 0.0 9.9e-13 48.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain DinB_2 PF12867.2 KEG14416.1 - 1.8e-09 38.0 0.0 4.3e-09 36.7 0.0 1.7 1 1 0 1 1 1 1 DinB superfamily Methyltransf_23 PF13489.1 KEG14416.1 - 1.3e-05 24.9 0.0 4.1e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEG14416.1 - 7.3e-05 23.3 0.0 0.0014 19.2 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEG14416.1 - 0.00047 19.7 0.0 0.054 13.0 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEG14416.1 - 0.00087 19.7 0.0 0.052 14.0 0.0 3.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEG14416.1 - 0.0023 18.3 0.0 0.21 12.1 0.0 2.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEG14416.1 - 0.22 10.8 0.0 0.53 9.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Peptidase_M28 PF04389.12 KEG14417.1 - 0.055 13.2 0.1 0.057 13.1 0.0 1.3 1 1 0 1 1 1 0 Peptidase family M28 ABC2_membrane PF01061.19 KEG14418.1 - 2.6e-10 39.8 13.9 4.6e-10 39.0 9.7 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 KEG14418.1 - 0.00053 20.3 0.0 0.00097 19.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter LETM1 PF07766.8 KEG14419.1 - 1.1e-39 136.1 2.2 5.6e-39 133.7 0.6 2.4 2 1 0 2 2 2 1 LETM1-like protein Peptidase_A22B PF04258.8 KEG14420.1 - 3.5e-55 187.5 16.1 5.5e-54 183.6 7.8 2.1 1 1 1 2 2 2 2 Signal peptide peptidase DUF1119 PF06550.6 KEG14420.1 - 0.00063 18.9 21.3 0.0045 16.1 14.8 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1119) IPPT PF01715.12 KEG14421.1 - 1.1e-41 142.5 0.0 6.4e-35 120.3 0.0 2.2 2 0 0 2 2 2 2 IPP transferase IPT PF01745.11 KEG14421.1 - 6.6e-06 25.4 0.0 0.015 14.4 0.0 3.1 3 0 0 3 3 3 2 Isopentenyl transferase PhoH PF02562.11 KEG14421.1 - 0.0016 17.7 0.0 0.0038 16.5 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein DUF2075 PF09848.4 KEG14421.1 - 0.0043 16.0 0.0 0.0069 15.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 KEG14421.1 - 0.0064 16.6 0.0 0.055 13.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KEG14421.1 - 0.0071 16.0 0.0 0.023 14.4 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain Zot PF05707.7 KEG14421.1 - 0.012 15.1 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_10 PF12846.2 KEG14421.1 - 0.027 13.9 0.0 0.11 11.9 0.0 2.0 1 1 0 1 1 1 0 AAA-like domain AAA_16 PF13191.1 KEG14421.1 - 0.036 14.0 0.0 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.1 KEG14421.1 - 0.041 13.7 0.2 1.5 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 KEG14421.1 - 0.087 12.5 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 KEG14421.1 - 0.14 12.9 0.0 0.57 11.0 0.0 2.2 1 1 0 1 1 1 0 AAA domain P12 PF12669.2 KEG14422.1 - 0.0059 16.7 0.6 0.0059 16.7 0.4 2.5 2 1 1 3 3 3 1 Virus attachment protein p12 family TctB PF07331.6 KEG14422.1 - 0.081 12.5 1.8 0.32 10.6 0.2 1.9 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family RVT_1 PF00078.22 KEG14423.1 - 2.3e-12 46.7 0.0 2.7e-12 46.5 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RRM_1 PF00076.17 KEG14426.1 - 4.1e-11 42.3 0.0 5.9e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG14426.1 - 2.7e-07 30.3 0.0 4.1e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG14426.1 - 9.4e-07 28.7 0.0 1.4e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Peptidase_M49 PF03571.10 KEG14427.1 - 0.15 10.0 0.0 0.16 9.9 0.0 1.0 1 0 0 1 1 1 0 Peptidase family M49 Tn7_Tnp_TnsA_C PF08721.6 KEG14428.1 - 0.021 14.8 0.0 0.053 13.5 0.0 1.8 1 0 0 1 1 1 0 TnsA endonuclease C terminal CtIP_N PF10482.4 KEG14428.1 - 0.066 12.9 3.2 0.04 13.6 0.6 1.9 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Flavi_DEAD PF07652.9 KEG14428.1 - 0.088 12.5 0.6 0.94 9.2 0.1 2.1 1 1 1 2 2 2 0 Flavivirus DEAD domain DUF342 PF03961.8 KEG14428.1 - 0.11 10.8 2.2 0.15 10.4 0.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF342) NPV_P10 PF05531.7 KEG14428.1 - 0.22 11.8 1.5 1.7 8.9 0.0 2.9 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.17 KEG14428.1 - 0.33 10.9 4.6 0.17 11.9 0.6 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Uso1_p115_C PF04871.8 KEG14428.1 - 0.85 9.5 6.0 8.1 6.3 0.5 2.4 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Peptidase_S46 PF10459.4 KEG14428.1 - 0.92 7.8 7.3 1.4 7.2 5.1 1.2 1 0 0 1 1 1 0 Peptidase S46 Mnd1 PF03962.10 KEG14428.1 - 2.1 7.9 6.7 1.1 8.8 1.0 2.0 1 1 1 2 2 2 0 Mnd1 family TPR_MLP1_2 PF07926.7 KEG14428.1 - 2.8 7.6 8.7 2.7 7.7 4.6 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Trichoplein PF13868.1 KEG14429.1 - 6e-57 192.6 129.4 6e-57 192.6 89.7 2.0 1 1 1 2 2 2 1 Tumour suppressor, Mitostatin TRAP_beta PF05753.9 KEG14431.1 - 2.2e-30 105.1 1.0 4.4e-30 104.1 0.7 1.4 1 1 0 1 1 1 1 Translocon-associated protein beta (TRAPB) DUF11 PF01345.13 KEG14431.1 - 3.7e-09 36.5 3.4 3.7e-09 36.5 2.3 2.1 2 0 0 2 2 2 1 Domain of unknown function DUF11 CARDB PF07705.6 KEG14431.1 - 7e-08 32.4 0.3 1e-07 31.8 0.2 1.3 1 0 0 1 1 1 1 CARDB NPCBM_assoc PF10633.4 KEG14431.1 - 0.016 15.2 0.4 0.036 14.1 0.3 1.6 1 1 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Gemini_AL1_M PF08283.6 KEG14432.1 - 0.076 12.8 0.1 0.38 10.6 0.0 2.0 2 0 0 2 2 2 0 Geminivirus rep protein central domain ELMO_CED12 PF04727.8 KEG14432.1 - 0.11 12.0 0.4 0.17 11.3 0.3 1.3 1 0 0 1 1 1 0 ELMO/CED-12 family tRNA-synt_1 PF00133.17 KEG14433.1 - 3e-184 613.4 0.0 1.3e-183 611.2 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KEG14433.1 - 1.6e-36 125.3 0.0 2.8e-36 124.5 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KEG14433.1 - 1.8e-15 56.5 0.1 3.4e-07 29.2 0.0 3.7 4 0 0 4 4 4 3 tRNA synthetases class I (M) Val_tRNA-synt_C PF10458.4 KEG14433.1 - 4.8e-14 52.1 2.8 4.8e-14 52.1 1.9 1.9 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1_2 PF13603.1 KEG14433.1 - 6e-06 25.6 0.1 0.036 13.3 0.0 2.4 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1d PF00750.14 KEG14433.1 - 0.019 13.7 0.0 1.7 7.3 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (R) tRNA-synt_1b PF00579.20 KEG14433.1 - 0.066 12.3 0.2 0.18 10.9 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Jag_N PF14804.1 KEG14433.1 - 0.11 12.5 0.2 0.34 10.9 0.1 1.8 1 0 0 1 1 1 0 Jag N-terminus MerR-DNA-bind PF09278.6 KEG14433.1 - 0.38 11.1 2.3 41 4.6 0.0 3.2 2 1 1 3 3 3 0 MerR, DNA binding SAM_decarbox PF01536.11 KEG14434.1 - 6.7e-20 71.0 0.0 4.5e-13 48.5 0.0 2.1 2 0 0 2 2 2 2 Adenosylmethionine decarboxylase SAM_decarbox PF01536.11 KEG14435.1 - 9.4e-112 372.9 0.0 1.1e-111 372.7 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase TPR_19 PF14559.1 KEG14436.1 - 0.29 11.5 1.9 1.1 9.6 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat RRM_1 PF00076.17 KEG14437.1 - 0.013 15.1 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG14437.1 - 0.068 13.1 0.0 0.21 11.6 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) GHMP_kinases_N PF00288.21 KEG14438.1 - 3.4e-13 49.4 0.1 8.8e-13 48.1 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KEG14438.1 - 3.4e-10 39.9 0.2 6.8e-10 39.0 0.1 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal M_domain PF12938.2 KEG14439.1 - 0.0025 17.6 1.3 0.0025 17.6 0.9 2.6 3 0 0 3 3 3 1 M domain of GW182 tRNA_m1G_MT PF01746.16 KEG14440.1 - 6.1e-25 87.8 0.0 1e-24 87.1 0.0 1.4 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Kinesin PF00225.18 KEG14441.1 - 7.2e-80 268.2 3.8 9.5e-80 267.7 0.0 2.3 2 0 0 2 2 2 1 Kinesin motor domain Pkinase PF00069.20 KEG14442.1 - 8.5e-67 225.0 0.0 1.3e-66 224.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG14442.1 - 2.5e-47 161.1 0.0 4e-47 160.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FUSC-like PF12805.2 KEG14442.1 - 0.016 14.1 0.0 0.032 13.1 0.0 1.4 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS Kinase-like PF14531.1 KEG14442.1 - 0.087 11.7 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF544 PF04424.8 KEG14443.1 - 8.7e-10 38.4 0.0 9.2e-09 35.1 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF544) eIF-3_zeta PF05091.7 KEG14444.1 - 2.4e-118 396.0 1.8 1.1e-116 390.4 1.2 2.0 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Nucleoplasmin PF03066.10 KEG14444.1 - 0.91 9.0 13.1 1.8 8.0 9.1 1.5 1 0 0 1 1 1 0 Nucleoplasmin DUF2457 PF10446.4 KEG14444.1 - 1.8 7.2 16.4 4 6.0 11.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Fer2_3 PF13085.1 KEG14446.1 - 5.7e-31 106.5 0.1 1e-30 105.7 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.22 KEG14446.1 - 0.021 14.5 1.1 0.021 14.5 0.7 2.0 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Mog1 PF04603.7 KEG14447.1 - 8.9e-24 84.0 0.0 9.7e-23 80.6 0.0 2.0 1 1 0 1 1 1 1 Ran-interacting Mog1 protein DUF2636 PF11120.3 KEG14448.1 - 0.1 12.1 11.3 0.16 11.4 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2636) DUF1275 PF06912.6 KEG14448.1 - 3.3 6.8 9.8 4.7 6.3 5.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1275) DEAD PF00270.24 KEG14449.1 - 4.1e-16 58.9 0.0 8.5e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEG14449.1 - 5.8e-10 38.8 0.0 1.3e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HHH_5 PF14520.1 KEG14449.1 - 0.00023 21.2 0.0 0.00067 19.7 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HxlR PF01638.12 KEG14449.1 - 0.0088 15.6 0.0 0.024 14.2 0.0 1.7 1 0 0 1 1 1 1 HxlR-like helix-turn-helix DUF4332 PF14229.1 KEG14449.1 - 0.063 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) Mito_carr PF00153.22 KEG14451.1 - 5.4e-39 131.8 10.3 3.3e-18 65.1 0.1 3.6 4 0 0 4 4 4 3 Mitochondrial carrier protein DUF2765 PF10963.3 KEG14451.1 - 0.041 13.8 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2765) Radical_SAM PF04055.16 KEG14453.1 - 2.5e-13 50.5 0.1 9.3e-13 48.6 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 KEG14453.1 - 2.9e-09 36.8 0.6 9.4e-09 35.1 0.3 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KEG14453.1 - 0.0014 18.6 0.3 0.0055 16.8 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Mito_fiss_reg PF05308.6 KEG14453.1 - 0.38 10.0 6.8 0.6 9.4 4.7 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 KEG14453.1 - 0.77 8.9 7.6 1.3 8.2 5.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Tail_P2_I PF09684.5 KEG14454.1 - 0.037 13.5 0.0 0.098 12.2 0.0 1.6 1 0 0 1 1 1 0 Phage tail protein (Tail_P2_I) US2 PF02476.10 KEG14454.1 - 0.13 12.7 0.0 2.9 8.4 0.0 2.5 2 0 0 2 2 2 0 US2 family DNA_pol_B PF00136.16 KEG14455.1 - 3.3e-80 270.1 0.0 4.9e-80 269.5 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KEG14455.1 - 4e-14 52.2 0.0 1.3e-07 30.8 0.0 3.2 3 0 0 3 3 3 3 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KEG14455.1 - 1.4e-06 28.2 1.2 4.3e-06 26.6 0.8 1.9 1 1 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta Lactamase_B_2 PF12706.2 KEG14456.1 - 3.2e-12 46.4 0.1 4.6e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KEG14456.1 - 2.7e-06 27.1 0.0 4.5e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily 4HBT_3 PF13622.1 KEG14457.1 - 0.00018 21.3 0.8 0.00028 20.6 0.6 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 KEG14457.1 - 0.001 19.1 0.5 0.0022 18.0 0.3 1.6 1 0 0 1 1 1 1 Thioesterase superfamily CART PF06373.6 KEG14457.1 - 0.1 12.5 0.2 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Cocaine and amphetamine regulated transcript protein (CART) YceI PF04264.8 KEG14458.1 - 3.3e-08 33.6 0.0 4.1e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 YceI-like domain Peptidase_C32 PF05411.7 KEG14458.1 - 0.065 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Equine arteritis virus putative proteinase Dynein_heavy PF03028.10 KEG14459.1 - 5.2e-201 669.3 0.0 5.2e-201 669.3 0.0 2.3 3 0 0 3 3 2 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 KEG14459.1 - 1.8e-119 398.8 5.4 1.8e-119 398.8 3.7 4.1 4 0 0 4 4 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 KEG14459.1 - 6.6e-96 320.3 0.0 1.9e-95 318.7 0.0 1.8 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 DHC_N1 PF08385.7 KEG14459.1 - 1.5e-83 281.1 0.0 1.5e-83 281.1 0.0 4.2 3 2 1 4 4 3 1 Dynein heavy chain, N-terminal region 1 AAA_8 PF12780.2 KEG14459.1 - 2.3e-73 246.4 0.0 1.3e-72 243.9 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 KEG14459.1 - 1.9e-53 180.6 1.9 4e-53 179.5 1.0 1.9 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_7 PF12775.2 KEG14459.1 - 1.6e-52 178.2 0.1 8.7e-52 175.8 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 MT PF12777.2 KEG14459.1 - 3.8e-41 140.9 13.8 3.8e-41 140.9 9.6 1.8 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 KEG14459.1 - 1.9e-26 92.4 0.4 2.8e-10 40.0 0.0 6.2 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA PF00004.24 KEG14459.1 - 7.5e-08 32.6 0.2 0.18 11.9 0.0 5.3 6 0 0 6 6 5 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEG14459.1 - 1.3e-05 25.2 4.8 0.91 9.4 0.0 6.1 5 0 0 5 5 4 1 AAA ATPase domain Sigma54_activat PF00158.21 KEG14459.1 - 3.1e-05 23.4 0.0 0.019 14.4 0.0 3.0 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_17 PF13207.1 KEG14459.1 - 0.0001 23.1 0.0 7.6 7.3 0.0 5.5 4 0 0 4 4 3 0 AAA domain RNA_helicase PF00910.17 KEG14459.1 - 0.0005 20.2 0.1 2 8.6 0.0 4.0 3 0 0 3 3 3 1 RNA helicase AAA_22 PF13401.1 KEG14459.1 - 0.00097 19.2 12.7 0.15 12.1 0.0 6.0 7 0 0 7 7 4 2 AAA domain AAA_19 PF13245.1 KEG14459.1 - 0.0012 18.5 4.3 2.1 8.1 0.5 3.8 3 0 0 3 3 3 1 Part of AAA domain AAA_18 PF13238.1 KEG14459.1 - 0.0022 18.2 6.3 7.2 6.9 0.0 5.8 5 0 0 5 5 4 0 AAA domain Mg_chelatase PF01078.16 KEG14459.1 - 0.0052 15.9 0.0 2.9 6.9 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.13 KEG14459.1 - 0.0083 15.6 0.1 1.3 8.5 0.0 2.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family MobB PF03205.9 KEG14459.1 - 0.041 13.6 0.8 7.7 6.2 0.0 3.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 KEG14459.1 - 0.06 12.9 4.4 17 5.0 0.0 3.9 4 0 0 4 4 3 0 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 KEG14459.1 - 0.37 10.3 0.3 31 4.2 0.0 3.0 3 0 0 3 3 3 0 P-loop containing region of AAA domain FA_hydroxylase PF04116.8 KEG14460.1 - 8.1e-13 48.7 24.2 8.1e-13 48.7 16.8 2.5 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Pkinase PF00069.20 KEG14462.1 - 9.8e-35 119.9 0.0 1.4e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG14462.1 - 5.8e-17 61.6 0.0 9e-17 60.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG14462.1 - 0.00025 20.0 0.0 0.0004 19.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 KEG14464.1 - 2.2e-09 36.8 0.0 3.7e-09 36.1 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG14464.1 - 3.8e-05 22.8 0.0 6.8e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG14464.1 - 0.0048 15.8 0.0 0.009 15.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like WBP-1 PF11669.3 KEG14464.1 - 0.34 11.0 4.6 0.18 11.8 1.2 2.0 1 1 1 2 2 2 0 WW domain-binding protein 1 Adap_comp_sub PF00928.16 KEG14465.1 - 1.5e-81 273.4 0.0 1.6e-81 273.2 0.0 1.0 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Dynein_heavy PF03028.10 KEG14468.1 - 1.4e-97 327.4 1.5 6e-97 325.3 0.0 2.5 2 1 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 KEG14468.1 - 4.8e-88 295.4 0.0 3.3e-87 292.6 0.0 2.5 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 KEG14468.1 - 2.2e-84 282.5 0.0 1.1e-82 277.0 0.0 2.5 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 KEG14468.1 - 5.9e-34 117.2 0.5 1e-25 90.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region D4 AAA_9 PF12781.2 KEG14468.1 - 4.4e-32 110.7 0.0 8.9e-32 109.7 0.0 1.4 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 KEG14468.1 - 4.6e-32 111.1 2.0 4.6e-32 111.1 1.4 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 KEG14468.1 - 7e-26 90.6 0.1 8.5e-11 41.7 0.0 7.1 4 2 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA PF00004.24 KEG14468.1 - 3.4e-18 66.1 0.0 0.00034 20.8 0.0 5.4 5 0 0 5 5 4 4 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.2 KEG14468.1 - 1.1e-14 54.2 0.0 3.2e-14 52.6 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 KEG14468.1 - 9.5e-12 45.1 5.9 0.0039 17.3 0.0 7.5 7 0 0 7 7 6 3 AAA domain AAA_33 PF13671.1 KEG14468.1 - 3.6e-09 36.6 0.0 0.95 9.3 0.0 5.8 4 0 0 4 4 4 3 AAA domain AAA_25 PF13481.1 KEG14468.1 - 8.4e-09 35.1 0.1 0.014 14.8 0.0 5.3 4 0 0 4 4 4 1 AAA domain AAA_17 PF13207.1 KEG14468.1 - 5.1e-08 33.7 0.2 0.47 11.2 0.0 5.7 5 0 0 5 5 4 2 AAA domain Sigma54_activat PF00158.21 KEG14468.1 - 6.8e-07 28.9 0.0 0.11 11.9 0.0 3.5 3 0 0 3 3 3 2 Sigma-54 interaction domain Zeta_toxin PF06414.7 KEG14468.1 - 1.7e-06 27.2 0.4 0.78 8.7 0.0 4.9 4 0 0 4 4 4 1 Zeta toxin AAA_18 PF13238.1 KEG14468.1 - 1.8e-05 25.0 0.0 3.2 8.0 0.0 4.9 4 0 0 4 4 4 1 AAA domain Mg_chelatase PF01078.16 KEG14468.1 - 3.2e-05 23.1 5.9 0.3 10.2 0.0 4.4 4 0 0 4 4 4 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KEG14468.1 - 4.7e-05 23.0 9.1 0.46 10.2 0.0 5.9 6 0 0 6 6 5 1 Part of AAA domain AAA_14 PF13173.1 KEG14468.1 - 0.00011 22.1 0.0 0.97 9.3 0.0 4.3 5 0 0 5 5 4 1 AAA domain RNA_helicase PF00910.17 KEG14468.1 - 0.00068 19.7 0.0 9.4 6.4 0.0 4.6 4 0 0 4 4 4 0 RNA helicase AAA_29 PF13555.1 KEG14468.1 - 0.003 17.0 1.1 25 4.4 0.0 4.2 4 0 0 4 4 4 0 P-loop containing region of AAA domain AAA_16 PF13191.1 KEG14468.1 - 0.0054 16.7 0.0 0.0054 16.7 0.0 10.1 10 1 0 10 10 8 3 AAA ATPase domain ABC_tran PF00005.22 KEG14468.1 - 0.028 14.7 7.3 23 5.2 0.0 5.1 5 0 0 5 5 4 0 ABC transporter MobB PF03205.9 KEG14468.1 - 0.089 12.5 0.2 26 4.5 0.0 4.1 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 KEG14468.1 - 0.09 12.4 0.0 2.8 7.5 0.0 3.4 3 0 0 3 3 3 0 Archaeal ATPase AAA_10 PF12846.2 KEG14468.1 - 0.14 11.5 7.2 2 7.7 0.0 5.3 6 0 0 6 6 4 0 AAA-like domain AAA_24 PF13479.1 KEG14468.1 - 0.27 10.7 0.2 57 3.2 0.0 3.7 4 0 0 4 4 4 0 AAA domain cobW PF02492.14 KEG14468.1 - 0.36 10.2 3.1 0.67 9.3 0.0 3.0 4 0 0 4 4 2 0 CobW/HypB/UreG, nucleotide-binding domain Peptidase_M8 PF01457.11 KEG14470.1 - 1.2e-129 433.0 0.0 1.4e-129 432.7 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin Reprolysin_5 PF13688.1 KEG14470.1 - 0.0076 16.1 0.1 0.014 15.3 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 CRAL_TRIO PF00650.15 KEG14471.1 - 2.1e-14 53.2 0.0 3.5e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 KEG14471.1 - 0.00039 20.3 0.0 0.0013 18.5 0.0 1.8 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain DUF382 PF04037.8 KEG14471.1 - 0.17 11.7 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF382) MBOAT_2 PF13813.1 KEG14472.1 - 0.00062 19.7 0.6 0.0011 18.9 0.4 1.4 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family V_ATPase_I PF01496.14 KEG14473.1 - 4.7 4.9 7.7 0.41 8.4 2.0 1.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family LSM PF01423.17 KEG14474.1 - 2.7e-13 49.2 0.2 3.3e-13 48.9 0.2 1.1 1 0 0 1 1 1 1 LSM domain Lpp-LpqN PF10738.4 KEG14474.1 - 0.044 13.0 0.0 0.046 12.9 0.0 1.1 1 0 0 1 1 1 0 Probable lipoprotein LpqN Arrestin_N PF00339.24 KEG14474.1 - 0.088 12.6 0.1 0.099 12.4 0.0 1.1 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain zf-C2H2_2 PF12756.2 KEG14475.1 - 1.4e-05 25.1 13.1 0.044 13.8 1.0 4.6 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 KEG14475.1 - 6.8e-05 22.9 21.2 0.0044 17.2 0.0 5.6 5 0 0 5 5 5 3 C2H2-type zinc finger DUF3421 PF11901.3 KEG14475.1 - 0.01 15.5 0.0 2.2 8.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3421) zf-C2H2 PF00096.21 KEG14475.1 - 0.012 15.9 2.5 0.11 12.9 0.3 6.5 7 0 0 7 7 7 0 Zinc finger, C2H2 type DUF1059 PF06348.6 KEG14475.1 - 0.042 13.6 0.1 0.14 11.9 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1059) zf-met PF12874.2 KEG14475.1 - 0.16 12.2 0.2 0.16 12.2 0.1 3.3 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 KEG14475.1 - 0.26 11.5 0.1 0.26 11.5 0.1 5.1 6 0 0 6 6 6 0 C2H2-type zinc-finger domain HypA PF01155.14 KEG14475.1 - 1.5 8.5 4.3 6.3 6.5 0.0 3.1 3 0 0 3 3 3 0 Hydrogenase expression/synthesis hypA family zf-H2C2_2 PF13465.1 KEG14475.1 - 1.6 9.1 19.8 2 8.8 0.0 6.4 7 0 0 7 7 7 0 Zinc-finger double domain Carn_acyltransf PF00755.15 KEG14478.1 - 2.9e-05 22.3 0.0 0.00019 19.6 0.0 1.9 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase RNB PF00773.14 KEG14479.1 - 3.8e-93 312.3 0.0 6e-93 311.6 0.0 1.3 1 0 0 1 1 1 1 RNB domain FAM176 PF14851.1 KEG14479.1 - 0.21 11.2 1.3 0.42 10.2 0.9 1.5 1 0 0 1 1 1 0 FAM176 family DUF4140 PF13600.1 KEG14481.1 - 0.046 14.1 0.4 0.046 14.1 0.3 6.3 3 2 4 7 7 7 0 N-terminal domain of unknown function (DUF4140) DASH_Dad3 PF08656.5 KEG14481.1 - 7.5 6.3 8.0 35 4.2 1.0 3.9 4 0 0 4 4 4 0 DASH complex subunit Dad3 Mucin PF01456.12 KEG14483.1 - 0.06 13.1 24.8 0.16 11.7 3.3 3.2 2 2 0 2 2 2 0 Mucin-like glycoprotein APG6 PF04111.7 KEG14483.1 - 1.7 7.5 34.1 0.28 10.1 0.4 2.3 2 0 0 2 2 2 0 Autophagy protein Apg6 CRT10 PF08728.5 KEG14483.1 - 3 5.7 9.4 4.2 5.2 6.5 1.2 1 0 0 1 1 1 0 CRT10 Asp-B-Hydro_N PF05279.6 KEG14483.1 - 7 6.4 43.9 1.2 8.9 24.2 2.1 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region Mucin PF01456.12 KEG14484.1 - 0.00014 21.6 3.4 0.00014 21.6 2.4 3.0 2 1 0 2 2 2 1 Mucin-like glycoprotein SPX PF03105.14 KEG14484.1 - 0.0025 17.6 5.3 0.0025 17.6 3.7 2.1 1 1 1 2 2 2 1 SPX domain ADIP PF11559.3 KEG14484.1 - 0.025 14.4 0.5 0.025 14.4 0.4 3.5 2 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 KEG14484.1 - 0.039 13.5 0.0 0.039 13.5 0.0 2.6 1 1 0 2 2 2 0 IncA protein Enkurin PF13864.1 KEG14484.1 - 0.2 11.8 0.2 0.2 11.8 0.1 4.4 2 2 1 4 4 4 0 Calmodulin-binding Baculo_PEP_C PF04513.7 KEG14484.1 - 0.47 10.2 7.5 0.35 10.6 0.7 3.1 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 KEG14484.1 - 4.1 6.5 8.4 0.61 9.2 1.1 2.4 2 1 0 2 2 2 0 Reovirus sigma C capsid protein V_ATPase_I PF01496.14 KEG14484.1 - 4.4 5.0 30.2 0.84 7.4 1.9 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Prenyltrans PF00432.16 KEG14485.1 - 6.6e-15 54.3 10.5 2.1e-09 36.7 0.1 5.5 5 1 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KEG14485.1 - 7.2e-06 26.3 0.0 0.037 14.4 0.0 2.9 1 1 2 3 3 3 3 Prenyltransferase-like Carb_anhydrase PF00194.16 KEG14487.1 - 1.7e-19 69.8 0.0 3.5e-19 68.7 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase RRXRR PF14239.1 KEG14488.1 - 0.07 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 RRXRR protein DUF4381 PF14316.1 KEG14488.1 - 0.098 12.7 0.1 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF4131 PF13567.1 KEG14488.1 - 0.38 10.1 1.6 0.6 9.5 0.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) TPR_11 PF13414.1 KEG14489.1 - 6.7e-17 60.8 3.2 1.6e-09 37.2 0.5 2.6 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KEG14489.1 - 1.3e-11 43.5 2.4 9.5e-06 25.1 0.1 3.9 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 KEG14489.1 - 3.3e-09 35.9 0.2 3.1e-05 23.3 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEG14489.1 - 5.8e-06 26.8 6.6 0.045 14.4 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEG14489.1 - 9.3e-06 25.0 1.0 0.014 15.1 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KEG14489.1 - 6.7e-05 22.3 1.4 0.015 15.0 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KEG14489.1 - 0.00075 19.9 0.1 0.12 13.1 0.0 3.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 KEG14489.1 - 0.0035 17.2 2.2 0.096 12.6 0.4 2.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 KEG14489.1 - 0.011 15.8 0.5 59 4.2 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 KEG14489.1 - 0.013 15.8 0.6 0.12 12.7 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.7 KEG14489.1 - 0.1 12.4 0.2 0.1 12.4 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEG14489.1 - 0.15 12.5 1.3 8.6 7.0 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-MYND PF01753.13 KEG14489.1 - 0.26 11.2 9.7 0.68 9.8 6.7 1.8 1 0 0 1 1 1 0 MYND finger Sel1 PF08238.7 KEG14489.1 - 1 10.1 4.0 22 5.8 0.6 2.7 2 0 0 2 2 2 0 Sel1 repeat Pkinase PF00069.20 KEG14492.1 - 8.1e-62 208.7 0.0 9.3e-62 208.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG14492.1 - 2.4e-39 134.9 0.0 2.9e-39 134.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG14492.1 - 1.3e-07 30.9 0.0 1.8e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KEG14492.1 - 0.0071 15.4 0.1 0.014 14.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KEG14492.1 - 0.01 15.2 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 KEG14492.1 - 0.016 14.9 0.1 0.03 14.0 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KEG14492.1 - 0.047 12.5 0.0 0.062 12.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 KEG14492.1 - 0.14 11.4 0.0 0.36 10.1 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Glyco_hydro_6 PF01341.12 KEG14492.1 - 0.17 11.3 0.0 0.25 10.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 6 AAA_23 PF13476.1 KEG14493.1 - 4.7e-21 76.0 0.0 4.7e-21 76.0 0.0 6.3 1 1 1 3 3 2 1 AAA domain SMC_N PF02463.14 KEG14493.1 - 1.9e-15 56.7 0.0 5.8e-15 55.1 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 KEG14493.1 - 1e-11 44.5 0.1 5.5e-11 42.2 0.0 2.3 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 KEG14493.1 - 4.9e-09 36.5 0.0 0.00085 19.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 KEG14493.1 - 7.3e-09 35.1 0.0 6.4e-05 22.1 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain Rad50_zn_hook PF04423.9 KEG14493.1 - 6.1e-05 22.4 3.0 0.0003 20.1 0.0 4.1 4 0 0 4 4 4 1 Rad50 zinc hook motif AAA_29 PF13555.1 KEG14493.1 - 0.00071 19.0 0.0 0.0016 17.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KEG14493.1 - 0.0013 19.0 0.0 0.0013 19.0 0.0 6.0 5 2 1 6 6 6 2 ABC transporter Reo_sigmaC PF04582.7 KEG14493.1 - 0.0026 17.0 20.2 0.046 12.8 0.2 5.5 4 2 0 5 5 5 2 Reovirus sigma C capsid protein Filo_VP35 PF02097.10 KEG14493.1 - 0.006 15.8 1.8 0.006 15.8 1.2 4.7 5 1 1 6 6 6 2 Filoviridae VP35 DUF948 PF06103.6 KEG14493.1 - 0.031 14.1 0.3 0.031 14.1 0.2 7.8 8 1 1 9 9 9 0 Bacterial protein of unknown function (DUF948) Baculo_IE-1 PF05290.6 KEG14493.1 - 0.042 13.5 0.1 0.22 11.2 0.0 2.3 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) NPV_P10 PF05531.7 KEG14493.1 - 0.048 13.9 39.7 1.5 9.1 1.3 9.6 7 3 3 10 10 10 0 Nucleopolyhedrovirus P10 protein zf-C2H2_jaz PF12171.3 KEG14493.1 - 0.06 13.4 0.3 0.18 11.9 0.0 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KEG14493.1 - 0.073 13.3 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type MMR_HSR1 PF01926.18 KEG14493.1 - 0.12 12.3 4.4 1.8 8.5 0.0 4.1 4 0 0 4 4 4 0 50S ribosome-binding GTPase AAA_22 PF13401.1 KEG14493.1 - 1.5 8.9 7.0 0.46 10.6 0.0 3.8 4 1 0 4 4 3 0 AAA domain Ribosomal_S26e PF01283.14 KEG14494.1 - 7.2e-40 135.7 3.3 7.6e-40 135.7 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Rad51 PF08423.6 KEG14495.1 - 1.2e-135 450.4 0.5 1.4e-135 450.1 0.3 1.0 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KEG14495.1 - 1.8e-14 53.5 0.0 2.6e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 KEG14495.1 - 7.7e-09 35.0 0.2 1.2e-08 34.4 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 KEG14495.1 - 1.1e-05 25.5 0.0 2.5e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain KaiC PF06745.8 KEG14495.1 - 1.7e-05 24.0 0.2 3.2e-05 23.1 0.1 1.5 1 1 0 1 1 1 1 KaiC AAA_22 PF13401.1 KEG14495.1 - 0.0067 16.5 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.10 KEG14495.1 - 0.031 13.1 0.1 0.066 12.0 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain PAXNEB PF05625.6 KEG14495.1 - 0.066 12.0 0.1 0.15 10.8 0.0 1.5 2 0 0 2 2 2 0 PAXNEB protein Proteasome PF00227.21 KEG14498.1 - 4e-45 153.4 0.1 4.8e-45 153.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KEG14498.1 - 5.7e-11 41.5 1.3 6.1e-11 41.4 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF2059 PF09832.4 KEG14499.1 - 0.044 13.8 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2059) zf-CCCH PF00642.19 KEG14499.1 - 0.086 12.5 0.2 0.18 11.5 0.2 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Exo_endo_phos PF03372.18 KEG14499.1 - 0.095 12.6 0.0 0.11 12.3 0.0 1.5 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Topoisom_bac PF01131.15 KEG14501.1 - 2.4e-22 79.3 0.0 6.2e-22 77.9 0.0 1.6 2 0 0 2 2 2 1 DNA topoisomerase Topoisom_bac PF01131.15 KEG14502.1 - 4.1e-55 187.2 0.1 6.6e-55 186.5 0.1 1.3 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 KEG14502.1 - 9.2e-15 54.4 0.0 2.9e-14 52.8 0.0 1.9 1 1 0 1 1 1 1 Toprim domain Toprim_4 PF13662.1 KEG14502.1 - 8.5e-05 22.4 0.0 0.00062 19.7 0.0 2.2 2 0 0 2 2 2 1 Toprim domain Toprim_2 PF13155.1 KEG14502.1 - 0.0084 16.4 0.0 0.03 14.6 0.0 1.9 1 0 0 1 1 1 1 Toprim-like Calpain_III PF01067.17 KEG14503.1 - 2.3e-45 153.8 0.0 1.3e-09 37.8 0.0 8.4 7 2 0 7 7 7 6 Calpain large subunit, domain III Peptidase_C2 PF00648.16 KEG14503.1 - 3.6e-33 114.8 0.2 6.1e-33 114.0 0.1 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease LRR_6 PF13516.1 KEG14503.1 - 0.056 13.5 0.1 63 4.1 0.0 3.6 3 0 0 3 3 3 0 Leucine Rich repeat MFS_1 PF07690.11 KEG14508.1 - 1.6e-14 53.3 28.9 9.4e-14 50.8 19.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily WD40 PF00400.27 KEG14510.1 - 1.1e-24 85.3 10.5 1.2e-09 37.6 0.0 7.7 7 1 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 KEG14510.1 - 0.00074 17.7 0.7 0.017 13.3 0.4 2.8 1 1 0 1 1 1 1 Nucleoporin Nup120/160 PQQ_3 PF13570.1 KEG14510.1 - 0.036 14.3 2.1 1.2 9.5 0.0 3.1 3 0 0 3 3 3 0 PQQ-like domain BNR PF02012.15 KEG14511.1 - 4.8e-06 25.6 0.2 2.3 8.4 0.1 5.0 4 0 0 4 4 4 2 BNR/Asp-box repeat PSII_BNR PF14870.1 KEG14511.1 - 0.1 11.5 0.0 0.8 8.6 0.0 2.2 2 0 0 2 2 2 0 Photosynthesis system II assembly factor YCF48 SNARE PF05739.14 KEG14512.1 - 0.0029 17.2 5.8 0.0029 17.2 4.0 2.2 3 0 0 3 3 3 1 SNARE domain PspA_IM30 PF04012.7 KEG14512.1 - 0.011 15.0 3.1 0.011 15.0 2.1 3.0 2 1 1 3 3 3 0 PspA/IM30 family V-SNARE_C PF12352.3 KEG14512.1 - 0.022 14.8 1.7 2.1 8.4 1.0 2.6 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus TrmB PF01978.14 KEG14512.1 - 0.046 13.4 1.4 0.18 11.5 0.0 2.5 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB DUF2203 PF09969.4 KEG14512.1 - 0.072 13.3 4.8 0.062 13.5 0.6 2.6 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) KxDL PF10241.4 KEG14512.1 - 0.082 12.8 2.0 0.36 10.7 0.5 2.5 1 1 0 2 2 2 0 Uncharacterized conserved protein Laminin_II PF06009.7 KEG14512.1 - 0.1 12.3 10.9 3.3 7.4 1.3 3.3 1 1 3 4 4 4 0 Laminin Domain II XhlA PF10779.4 KEG14512.1 - 0.21 11.4 0.1 0.21 11.4 0.1 2.7 2 1 1 3 3 3 0 Haemolysin XhlA V_ATPase_I PF01496.14 KEG14512.1 - 0.95 7.2 6.8 4.8 4.8 3.9 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DMPK_coil PF08826.5 KEG14512.1 - 1.9 8.4 10.8 0.6 10.0 0.1 3.1 3 1 0 3 3 3 0 DMPK coiled coil domain like DUF745 PF05335.8 KEG14512.1 - 2.2 7.7 8.9 5.3 6.5 3.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF745) DUF1664 PF07889.7 KEG14512.1 - 3.1 7.6 10.2 2 8.2 1.1 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) Sec2p PF06428.6 KEG14512.1 - 8.2 6.3 11.3 0.57 10.0 1.3 2.9 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p AAT PF03417.11 KEG14513.1 - 0.00076 18.9 0.7 0.073 12.5 0.0 2.3 2 0 0 2 2 2 2 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase E2R135 PF11570.3 KEG14513.1 - 0.0048 17.0 4.5 0.0048 17.0 3.1 2.1 2 0 0 2 2 2 1 Coiled-coil receptor-binding R-domain of colicin E2 WXG100 PF06013.7 KEG14513.1 - 0.02 14.8 0.4 0.1 12.6 0.3 2.2 1 0 0 1 1 1 0 Proteins of 100 residues with WXG DUF4279 PF14106.1 KEG14513.1 - 0.024 14.5 0.1 9.1 6.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) GTPase_Cys_C PF12631.2 KEG14513.1 - 0.1 12.9 0.2 0.3 11.5 0.0 1.9 2 0 0 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Cytochrome-c551 PF10643.4 KEG14513.1 - 3.6 6.8 7.0 26 4.0 4.4 2.2 1 1 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Sec8_exocyst PF04048.9 KEG14513.1 - 4.9 6.7 9.0 0.46 10.0 0.3 2.8 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain WXG100 PF06013.7 KEG14514.1 - 0.088 12.8 0.6 0.75 9.8 0.0 2.5 2 0 0 2 2 2 0 Proteins of 100 residues with WXG zf-rbx1 PF12678.2 KEG14516.1 - 4.8e-34 116.2 12.4 5.9e-34 116.0 8.6 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KEG14516.1 - 1.8e-17 62.9 9.7 2.2e-17 62.6 6.7 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 KEG14516.1 - 6.1e-07 29.1 12.8 3.4e-06 26.7 8.9 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KEG14516.1 - 0.00013 21.5 9.0 0.021 14.4 6.7 2.2 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEG14516.1 - 0.0004 19.9 11.7 0.0025 17.4 8.1 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KEG14516.1 - 0.044 13.7 8.2 0.13 12.2 5.8 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_2 PF13923.1 KEG14516.1 - 0.069 13.1 13.0 0.062 13.3 5.6 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H_2 PF13832.1 KEG14516.1 - 0.075 13.0 9.7 0.12 12.4 6.7 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_5 PF14634.1 KEG14516.1 - 0.18 11.5 12.6 2.8 7.7 8.8 2.6 1 1 1 2 2 2 0 zinc-RING finger domain zf-Nse PF11789.3 KEG14516.1 - 0.19 11.2 2.5 0.32 10.5 1.8 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-HC5HC2H PF13771.1 KEG14516.1 - 0.19 11.8 10.9 3.8 7.7 7.6 2.1 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_UBOX PF13445.1 KEG14516.1 - 3.1 7.5 7.0 30 4.4 4.9 2.2 1 1 0 1 1 1 0 RING-type zinc-finger Baculo_RING PF05883.6 KEG14516.1 - 9.4 6.0 6.7 25 4.6 4.6 1.7 1 1 0 1 1 1 0 Baculovirus U-box/Ring-like domain Methyltransf_23 PF13489.1 KEG14517.1 - 4.5e-10 39.4 0.0 6.5e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEG14517.1 - 8.1e-10 39.0 0.0 2e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEG14517.1 - 1.2e-08 35.4 0.0 8.2e-08 32.8 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEG14517.1 - 3.4e-06 26.7 0.1 5.6e-05 22.7 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEG14517.1 - 6.8e-05 23.2 0.1 0.0013 19.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEG14517.1 - 0.00022 21.5 0.1 0.00082 19.6 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEG14517.1 - 0.0014 18.6 0.0 0.014 15.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain TPMT PF05724.6 KEG14517.1 - 0.0086 15.5 0.0 0.097 12.0 0.0 2.2 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.1 KEG14517.1 - 0.073 12.7 0.0 0.42 10.2 0.0 2.2 1 1 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 KEG14517.1 - 0.1 11.9 0.0 0.39 10.0 0.0 1.9 3 0 0 3 3 3 0 Methyltransferase small domain Helicase_C PF00271.26 KEG14518.1 - 4.3e-20 71.3 0.0 8.4e-20 70.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 KEG14518.1 - 8.7e-13 47.6 1.5 5.4e-12 45.0 0.2 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4217) Acetyltransf_1 PF00583.19 KEG14519.1 - 1.8e-13 50.2 0.1 2.8e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KEG14519.1 - 8.7e-10 38.2 0.0 1.4e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KEG14519.1 - 6.3e-06 26.2 0.0 1.2e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KEG14519.1 - 2.3e-05 24.4 0.0 3.7e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KEG14519.1 - 0.025 14.4 0.0 0.056 13.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KEG14519.1 - 0.038 13.8 0.0 0.051 13.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 KEG14519.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RHSP PF07999.6 KEG14520.1 - 7.3e-93 311.5 0.0 1.2e-92 310.7 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon hot spot protein Ank_2 PF12796.2 KEG14521.1 - 1.6e-05 25.1 0.0 0.00053 20.2 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KEG14521.1 - 0.00042 20.4 0.6 1.4 9.2 0.1 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 KEG14521.1 - 0.0069 16.1 0.0 29 4.7 0.0 4.1 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.1 KEG14521.1 - 0.058 13.6 0.0 75 4.0 0.0 4.4 4 0 0 4 4 4 0 Ankyrin repeat RRM_6 PF14259.1 KEG14522.1 - 0.0003 20.7 0.0 0.00059 19.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEG14522.1 - 0.0048 16.4 0.0 0.0097 15.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG14522.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4611 PF15387.1 KEG14522.1 - 0.29 11.2 2.7 3 8.0 1.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) ThiF PF00899.16 KEG14524.1 - 9.8e-35 119.3 0.2 1.5e-34 118.7 0.1 1.3 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 KEG14524.1 - 3.6e-15 55.2 0.0 6e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KEG14524.1 - 2.2e-09 36.5 0.6 4.6e-09 35.5 0.4 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 KEG14524.1 - 0.0037 17.3 0.0 0.0088 16.1 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 KEG14524.1 - 0.055 12.3 0.0 0.14 11.0 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 KEG14524.1 - 0.065 13.6 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Saccharop_dh PF03435.13 KEG14524.1 - 0.12 11.3 0.1 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase DUF3439 PF11921.3 KEG14525.1 - 7.5 6.3 11.3 3.3 7.4 4.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) CC2D2AN-C2 PF15625.1 KEG14526.1 - 3.8e-10 39.5 0.1 8.5e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 CC2D2A N-terminal C2 domain C2 PF00168.25 KEG14526.1 - 0.0036 17.1 0.0 0.0098 15.7 0.0 1.7 1 0 0 1 1 1 1 C2 domain DUF4336 PF14234.1 KEG14527.1 - 0.022 13.9 0.1 0.095 11.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4336) Pkinase PF00069.20 KEG14528.1 - 4.5e-24 84.9 0.0 1.8e-12 46.9 0.0 4.2 4 1 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEG14528.1 - 0.0003 19.9 0.0 0.24 10.4 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase Ribosomal_60s PF00428.14 KEG14528.1 - 8.2 6.9 11.5 37 4.8 8.0 2.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein Hexapep PF00132.19 KEG14529.1 - 0.007 15.8 8.6 0.58 9.7 0.0 4.3 4 0 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) DEAD PF00270.24 KEG14530.1 - 3.3e-37 127.5 0.0 8.3e-37 126.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEG14530.1 - 6.1e-27 93.2 0.2 4.2e-26 90.6 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1460 PF07313.7 KEG14530.1 - 0.0017 17.6 0.1 1.3 8.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1460) CMS1 PF14617.1 KEG14530.1 - 0.0034 16.4 0.0 0.01 14.9 0.0 1.8 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit B2 PF11473.3 KEG14530.1 - 0.0039 16.7 0.6 1.4 8.5 0.1 2.5 1 1 1 2 2 2 2 RNA binding protein B2 AAA_22 PF13401.1 KEG14530.1 - 0.024 14.7 0.8 0.18 11.9 0.0 2.7 3 1 0 3 3 3 0 AAA domain TIR_2 PF13676.1 KEG14530.1 - 0.077 13.1 0.1 1.6 8.9 0.0 2.3 1 1 1 2 2 2 0 TIR domain DUF3128 PF11326.3 KEG14531.1 - 6e-13 48.7 0.0 1e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) HYLS1_C PF15311.1 KEG14531.1 - 9.9e-05 22.4 1.0 0.00021 21.4 0.7 1.5 1 0 0 1 1 1 1 Hydrolethalus syndrome protein 1 C-terminus BK_channel_a PF03493.13 KEG14532.1 - 1.1e-22 79.8 0.0 2.2e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit CP_ATPgrasp_1 PF04174.8 KEG14532.1 - 0.07 11.7 0.0 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 A circularly permuted ATPgrasp RVT_1 PF00078.22 KEG14533.1 - 1.9e-38 132.0 0.0 3.8e-38 131.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 KEG14533.1 - 3.6e-16 59.7 0.0 7.8e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 KEG14533.1 - 5.9e-05 22.6 0.0 0.00015 21.3 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-C2H2_4 PF13894.1 KEG14533.1 - 0.035 14.4 35.7 0.38 11.2 0.2 7.4 7 0 0 7 7 7 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KEG14533.1 - 0.78 10.2 37.0 0.95 9.9 0.2 6.4 6 0 0 6 6 6 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 KEG14533.1 - 0.99 9.5 14.8 26 4.9 0.1 5.5 3 2 2 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KEG14533.1 - 2.1 8.5 10.6 16 5.8 0.0 5.5 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding Cytomega_gL PF01801.11 KEG14535.1 - 0.12 11.8 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein L CagA PF03507.8 KEG14536.1 - 0.0054 16.6 0.5 0.19 11.5 0.0 2.1 2 0 0 2 2 2 1 CagA exotoxin PspB PF06667.7 KEG14536.1 - 0.053 13.4 6.1 0.46 10.4 1.8 2.5 2 1 0 2 2 2 0 Phage shock protein B Fib_alpha PF08702.5 KEG14536.1 - 0.063 13.4 5.1 0.27 11.3 3.4 2.1 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF3323 PF11796.3 KEG14536.1 - 0.75 9.0 11.7 0.031 13.5 2.9 1.9 1 1 1 2 2 2 0 Protein of unknown function N-terminus (DUF3323) Striatin PF08232.7 KEG14536.1 - 1.4 9.2 13.2 1.3 9.3 0.9 2.2 1 1 1 2 2 2 0 Striatin family Toxin_39 PF15500.1 KEG14536.1 - 1.5 8.9 8.0 5.4 7.2 1.2 2.2 1 1 1 2 2 2 0 Putative RNase-like toxin IncA PF04156.9 KEG14536.1 - 1.9 8.0 16.8 35 3.9 11.6 2.0 1 1 0 1 1 1 0 IncA protein Lge1 PF11488.3 KEG14536.1 - 2 8.6 6.3 0.9 9.7 2.2 2.0 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 DUF4250 PF14056.1 KEG14536.1 - 2.4 7.9 4.7 6.9 6.4 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) Med9 PF07544.8 KEG14536.1 - 3.1 7.5 8.1 3.2 7.5 0.7 2.4 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 TBPIP PF07106.8 KEG14536.1 - 4 6.9 7.7 1.3 8.5 2.6 1.8 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Prefoldin_2 PF01920.15 KEG14536.1 - 4.1 7.2 11.6 41 3.9 7.9 2.3 1 1 0 1 1 1 0 Prefoldin subunit DivIVA PF05103.8 KEG14536.1 - 7.2 6.6 10.7 1.1 9.3 1.0 2.4 1 1 1 2 2 2 0 DivIVA protein Atg14 PF10186.4 KEG14536.1 - 9.7 5.0 14.7 5.5 5.8 8.0 1.8 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DEAD PF00270.24 KEG14537.1 - 1.4e-40 138.5 0.1 4.1e-38 130.5 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KEG14537.1 - 1.3e-27 95.4 0.0 2.7e-27 94.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 KEG14537.1 - 0.0027 16.8 0.0 0.0057 15.7 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Helicase_C_2 PF13307.1 KEG14537.1 - 0.0061 16.5 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain RraB PF06877.6 KEG14537.1 - 0.12 13.0 0.0 0.28 11.8 0.0 1.7 1 0 0 1 1 1 0 Regulator of ribonuclease activity B FUSC PF04632.7 KEG14538.1 - 3.4 5.9 8.7 0.8 8.0 2.8 1.8 2 0 0 2 2 2 0 Fusaric acid resistance protein family TPR_1 PF00515.23 KEG14539.1 - 0.18 11.4 2.8 6.1 6.6 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 KEG14539.1 - 0.39 10.7 4.6 4.2 7.5 0.5 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat SNARE PF05739.14 KEG14540.1 - 5.7e-16 57.9 0.7 5.7e-16 57.9 0.5 3.1 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 KEG14540.1 - 6.8e-10 39.0 1.5 6.8e-10 39.0 1.0 2.7 3 1 0 3 3 2 1 Syntaxin Syntaxin_2 PF14523.1 KEG14540.1 - 0.0035 17.3 12.3 0.054 13.5 2.3 3.0 2 1 1 3 3 3 2 Syntaxin-like protein Herpes_US9 PF06072.6 KEG14540.1 - 0.022 14.5 1.4 0.022 14.5 1.0 2.1 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 CCP_MauG PF03150.9 KEG14540.1 - 0.065 13.5 5.2 0.036 14.3 1.8 1.8 1 1 1 2 2 2 0 Di-haem cytochrome c peroxidase DUF4226 PF10774.4 KEG14540.1 - 0.28 11.2 6.5 0.17 11.9 0.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4226) Laminin_II PF06009.7 KEG14540.1 - 0.31 10.7 8.4 0.75 9.5 0.3 2.9 2 1 1 3 3 3 0 Laminin Domain II DASH_Duo1 PF08651.5 KEG14540.1 - 0.36 10.4 4.5 2.2 7.9 0.2 3.4 3 1 0 3 3 3 0 DASH complex subunit Duo1 DUF2951 PF11166.3 KEG14540.1 - 1.1 9.1 10.5 0.25 11.2 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2951) DUF1664 PF07889.7 KEG14540.1 - 1.1 9.0 8.3 3.8 7.3 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.6 KEG14540.1 - 1.3 8.9 6.1 8.8 6.3 0.5 3.5 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) G10 PF01125.12 KEG14540.1 - 3.2 7.2 6.7 0.45 10.0 0.6 2.3 1 1 0 2 2 2 0 G10 protein Cor1 PF04803.7 KEG14540.1 - 5.9 6.6 14.8 0.54 10.0 4.3 2.4 2 1 0 2 2 2 0 Cor1/Xlr/Xmr conserved region CoA_binding_3 PF13727.1 KEG14541.1 - 0.091 12.5 1.1 0.14 11.9 0.7 1.3 1 0 0 1 1 1 0 CoA-binding domain Coa1 PF08695.5 KEG14541.1 - 0.098 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 DUF1212 PF06738.7 KEG14541.1 - 0.2 11.1 5.9 0.29 10.5 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) Gluconate_2-dh3 PF13618.1 KEG14548.1 - 0.026 14.6 0.0 0.06 13.5 0.0 1.6 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 ATP-grasp_4 PF13535.1 KEG14550.1 - 2.9e-29 102.1 0.1 1.3e-19 70.6 0.0 2.4 1 1 1 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 KEG14550.1 - 1.3e-08 33.9 0.1 5.6e-07 28.6 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 KEG14550.1 - 7.7e-07 29.1 0.0 2.3e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.6 KEG14550.1 - 0.034 13.6 0.0 0.072 12.5 0.0 1.5 1 0 0 1 1 1 0 RimK-like ATP-grasp domain CPSase_L_D2 PF02786.12 KEG14550.1 - 0.035 13.3 0.0 0.11 11.7 0.0 1.7 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain SKI PF01202.17 KEG14551.1 - 5.1e-09 36.1 0.0 6.2e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.1 KEG14551.1 - 3.4e-07 30.2 0.0 4.4e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEG14551.1 - 9.5e-07 29.6 0.0 1.1e-06 29.3 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KEG14551.1 - 0.0014 18.9 0.0 0.0019 18.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KEG14551.1 - 0.0019 18.3 0.1 0.0081 16.3 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.1 KEG14551.1 - 0.0036 17.2 0.0 0.0063 16.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KEG14551.1 - 0.013 15.0 0.1 0.023 14.2 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 KEG14551.1 - 0.019 14.6 0.1 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KEG14551.1 - 0.021 14.8 0.4 0.046 13.6 0.2 1.6 1 1 0 1 1 1 0 AAA ATPase domain ETF PF01012.16 KEG14551.1 - 0.023 14.4 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Electron transfer flavoprotein domain DUF258 PF03193.11 KEG14551.1 - 0.033 13.3 0.0 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 KEG14551.1 - 0.041 13.4 0.0 0.054 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KEG14551.1 - 0.046 13.9 0.0 0.086 13.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 KEG14551.1 - 0.058 13.6 0.0 0.086 13.1 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Cytidylate_kin2 PF13189.1 KEG14551.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase-like family AAA_25 PF13481.1 KEG14551.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KEG14551.1 - 0.14 12.3 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 KEG14551.1 - 0.15 11.7 0.6 0.32 10.7 0.4 1.7 1 1 0 1 1 1 0 Part of AAA domain WD40 PF00400.27 KEG14552.1 - 3.9e-47 156.5 28.0 7.7e-07 28.7 0.7 11.2 11 0 0 11 11 11 9 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KEG14552.1 - 0.0002 20.2 0.8 0.0037 16.0 0.0 3.0 2 1 2 4 4 4 1 Nup133 N terminal like Gmad1 PF10647.4 KEG14552.1 - 0.0086 15.4 0.9 0.097 12.0 0.1 2.7 3 0 0 3 3 3 1 Lipoprotein LpqB beta-propeller domain Amastin PF07344.6 KEG14553.1 - 0.12 11.9 11.2 0.091 12.3 6.3 1.7 1 1 1 2 2 2 0 Amastin surface glycoprotein AA_permease PF00324.16 KEG14554.1 - 3.1e-46 157.6 39.3 4.6e-46 157.1 27.2 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KEG14554.1 - 1.4e-17 63.4 47.7 2.1e-17 62.7 33.1 1.3 1 0 0 1 1 1 1 Amino acid permease ETF_alpha PF00766.14 KEG14555.1 - 1.5e-33 114.2 1.3 4.7e-33 112.6 0.0 2.2 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.16 KEG14555.1 - 1e-29 103.3 5.5 2e-29 102.3 3.8 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Spore_YtfJ PF09579.5 KEG14555.1 - 0.47 10.3 3.3 1.9 8.4 0.2 2.8 2 1 0 2 2 2 0 Sporulation protein YtfJ (Spore_YtfJ) AMP-binding PF00501.23 KEG14556.1 - 9.1e-58 195.6 0.3 2.1e-56 191.1 0.2 2.6 2 1 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEG14556.1 - 7.8e-10 39.5 0.1 2.6e-09 37.8 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain RasGEF_N PF00618.15 KEG14558.1 - 1.4e-12 47.6 0.2 3.2e-12 46.4 0.1 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif RasGEF PF00617.14 KEG14558.1 - 0.005 16.5 0.0 0.0085 15.8 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain DUF1133 PF06576.6 KEG14560.1 - 0.19 10.8 0.0 0.47 9.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1133) DUF3733 PF12534.3 KEG14561.1 - 0.012 14.8 1.0 0.15 11.3 0.1 2.3 1 1 1 2 2 2 0 Leucine-rich repeat containing protein 8 COX6B PF02297.12 KEG14562.1 - 2e-14 53.3 2.2 2.2e-14 53.2 1.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb DUF753 PF05444.7 KEG14562.1 - 0.034 14.0 0.4 0.041 13.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF753) Rab5ip PF07019.7 KEG14563.1 - 2.8e-18 65.8 4.1 3.4e-18 65.5 2.9 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Aph-1 PF06105.7 KEG14563.1 - 0.064 12.4 0.5 0.096 11.9 0.4 1.2 1 0 0 1 1 1 0 Aph-1 protein BTP PF05232.7 KEG14563.1 - 0.27 11.0 0.2 0.27 11.0 0.1 2.1 2 0 0 2 2 2 0 Bacterial Transmembrane Pair family Med9 PF07544.8 KEG14564.1 - 5.3 6.8 11.4 7 6.4 1.4 4.3 4 0 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 LRR_4 PF12799.2 KEG14565.1 - 4.7e-22 77.1 7.1 1e-09 37.8 0.8 3.6 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG14565.1 - 3e-11 42.8 27.9 3.2e-05 23.5 2.4 3.5 1 1 3 4 4 4 4 Leucine rich repeat LRR_6 PF13516.1 KEG14565.1 - 8.4e-08 31.5 10.4 1.1 9.5 0.2 6.0 5 1 1 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.28 KEG14565.1 - 2.8e-07 29.6 12.4 4.5 7.6 0.0 6.8 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 KEG14565.1 - 1.9e-05 24.1 7.6 11 6.7 0.1 6.4 6 0 0 6 6 6 2 Leucine rich repeat LRR_9 PF14580.1 KEG14565.1 - 2e-05 24.2 0.0 3.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Leucine-rich repeat TMEM190 PF15431.1 KEG14565.1 - 0.011 15.6 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 190 MMR_HSR1 PF01926.18 KEG14566.1 - 9.4e-14 51.3 0.0 1.8e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KEG14566.1 - 2.9e-07 30.1 0.0 0.00038 19.9 0.0 2.6 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KEG14566.1 - 5.5e-06 25.6 0.0 1.7e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 KEG14566.1 - 0.0062 15.8 0.0 0.038 13.2 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B NPBW PF15180.1 KEG14566.1 - 0.037 13.6 0.2 0.11 12.1 0.2 1.8 1 0 0 1 1 1 0 Neuropeptides B and W DnaJ PF00226.26 KEG14567.1 - 4e-23 80.9 0.2 8.6e-23 79.8 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain SPATIAL PF15256.1 KEG14567.1 - 0.36 10.8 3.1 0.55 10.2 2.2 1.3 1 0 0 1 1 1 0 SPATIAL MAP7 PF05672.6 KEG14567.1 - 1.3 8.3 27.5 2.1 7.7 19.0 1.3 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Metallophos PF00149.23 KEG14568.1 - 4e-37 127.5 0.1 5e-37 127.2 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Herpes_UL55 PF04537.7 KEG14568.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL55 protein Ras PF00071.17 KEG14569.1 - 5.8e-11 42.0 0.1 1.1e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEG14569.1 - 1.7e-05 25.3 0.0 4.1e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 KEG14569.1 - 0.00046 19.3 0.0 0.00076 18.6 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region IBR PF01485.16 KEG14569.1 - 0.047 13.5 0.1 0.095 12.5 0.1 1.4 1 0 0 1 1 1 0 IBR domain Hen1_L PF12623.2 KEG14570.1 - 0.11 11.2 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 RNA repair, ligase-Pnkp-associating, region of Hen1 zf-MIZ PF02891.15 KEG14571.1 - 8.8e-09 34.7 6.5 8.8e-09 34.7 4.5 2.2 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 KEG14571.1 - 0.0012 18.3 2.2 0.003 17.0 1.5 1.8 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF3115 PF11312.3 KEG14571.1 - 0.18 10.6 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3115) Auto_anti-p27 PF06677.7 KEG14571.1 - 1.2 8.9 6.7 0.11 12.3 0.6 2.2 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-TFIIB PF13453.1 KEG14571.1 - 1.7 7.9 8.4 1.2 8.4 3.1 2.5 2 0 0 2 2 2 0 Transcription factor zinc-finger RRN7 PF11781.3 KEG14571.1 - 2.1 7.9 8.8 4.7 6.8 0.1 3.1 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 ABC_tran PF00005.22 KEG14572.1 - 1.2e-35 122.8 0.1 6e-35 120.5 0.0 2.2 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 KEG14572.1 - 1.4e-15 57.4 6.5 1.9e-15 57.0 4.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 KEG14572.1 - 5e-07 29.9 0.0 3.6e-05 23.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 KEG14572.1 - 3.5e-06 26.4 0.8 0.00076 18.7 0.0 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KEG14572.1 - 0.0002 21.3 0.0 0.00051 20.0 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 KEG14572.1 - 0.0015 18.0 1.2 0.0035 16.8 0.1 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 KEG14572.1 - 0.0028 18.4 0.1 0.0065 17.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KEG14572.1 - 0.0058 16.7 0.1 0.06 13.4 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KEG14572.1 - 0.011 15.5 0.0 0.029 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KEG14572.1 - 0.014 14.6 0.0 0.047 12.8 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 KEG14572.1 - 0.034 14.4 0.1 0.14 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 KEG14572.1 - 0.057 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 KEG14572.1 - 0.091 13.0 2.6 0.11 12.7 0.1 2.4 3 0 0 3 3 2 0 AAA domain MMR_HSR1 PF01926.18 KEG14572.1 - 0.098 12.6 0.3 0.46 10.4 0.0 2.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase G-alpha PF00503.15 KEG14572.1 - 0.23 10.0 0.0 0.23 10.0 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit IncA PF04156.9 KEG14574.1 - 0.03 13.9 14.1 0.067 12.7 2.3 2.5 2 0 0 2 2 2 0 IncA protein Phage_GP20 PF06810.6 KEG14574.1 - 0.038 13.4 2.8 2.5 7.5 0.0 2.3 2 0 0 2 2 2 0 Phage minor structural protein GP20 Spc7 PF08317.6 KEG14574.1 - 0.78 8.3 7.4 0.46 9.0 0.4 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein V_ATPase_I PF01496.14 KEG14574.1 - 2.7 5.7 6.3 0.66 7.7 1.0 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Seryl_tRNA_N PF02403.17 KEG14574.1 - 3 7.9 10.7 2 8.4 0.2 3.6 2 2 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Spc24 PF08286.6 KEG14574.1 - 3.1 7.5 6.5 2 8.1 0.4 2.6 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Siah-Interact_N PF09032.6 KEG14574.1 - 3.4 7.8 15.0 0.18 11.8 3.0 3.1 2 2 1 3 3 3 0 Siah interacting protein, N terminal DUF1192 PF06698.6 KEG14574.1 - 10 6.0 12.9 2.7 7.8 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) FSH1 PF03959.8 KEG14575.1 - 1.4e-22 80.1 0.1 3e-21 75.8 0.0 2.2 2 0 0 2 2 2 1 Serine hydrolase (FSH1) MMR_HSR1_C PF08438.5 KEG14575.1 - 1.9e-22 79.5 0.0 4.7e-22 78.2 0.0 1.7 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 KEG14575.1 - 1.6e-14 53.8 0.0 3.8e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RWD PF05773.17 KEG14575.1 - 5.1e-07 29.5 0.0 1.5e-06 28.0 0.0 1.8 1 1 1 2 2 2 1 RWD domain Abhydrolase_5 PF12695.2 KEG14575.1 - 0.00012 21.8 0.4 0.00047 19.9 0.1 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family FeoB_N PF02421.13 KEG14575.1 - 0.00034 19.9 0.1 0.0041 16.3 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Abhydrolase_6 PF12697.2 KEG14575.1 - 0.029 14.2 2.3 0.22 11.3 1.6 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family PE-PPE PF08237.6 KEG14575.1 - 0.089 12.2 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain GTP_EFTU PF00009.22 KEG14575.1 - 0.1 12.0 0.0 5.9 6.2 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 KEG14575.1 - 0.23 10.9 0.0 14 5.1 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AA_kinase PF00696.23 KEG14576.1 - 1.3e-34 119.7 0.2 4.5e-34 118.0 0.0 1.9 2 0 0 2 2 2 1 Amino acid kinase family Aldedh PF00171.17 KEG14576.1 - 4.3e-14 51.6 5.5 5.8e-12 44.6 2.0 2.5 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Chal_sti_synt_N PF00195.14 KEG14580.1 - 0.02 14.1 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain Pkinase_Tyr PF07714.12 KEG14582.1 - 5.8e-12 45.2 0.1 3.3e-11 42.7 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KEG14582.1 - 3.4e-08 32.9 0.0 4e-07 29.4 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KEG14582.1 - 0.098 11.5 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like zf-MYND PF01753.13 KEG14584.1 - 0.005 16.6 3.3 0.0089 15.8 2.3 1.4 1 0 0 1 1 1 1 MYND finger PHF5 PF03660.9 KEG14584.1 - 0.17 11.9 1.1 0.39 10.7 0.8 1.5 1 0 0 1 1 1 0 PHF5-like protein CDP-OH_P_transf PF01066.16 KEG14586.1 - 5.7e-18 65.0 2.4 5.7e-18 65.0 1.7 2.7 4 0 0 4 4 4 1 CDP-alcohol phosphatidyltransferase ABC2_membrane_3 PF12698.2 KEG14588.1 - 0.064 12.2 3.1 1.5 7.7 0.0 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein YwiC PF14256.1 KEG14588.1 - 0.24 11.5 9.6 0.71 9.9 1.4 2.7 3 0 0 3 3 3 0 YwiC-like protein 6PF2K PF01591.13 KEG14589.1 - 2.6e-62 209.7 0.0 4.4e-62 209.0 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase Ank PF00023.25 KEG14589.1 - 5.7e-15 54.2 1.2 1.2e-09 37.4 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 KEG14589.1 - 6e-15 55.3 0.2 1.9e-14 53.7 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEG14589.1 - 7.5e-14 51.8 1.7 5.2e-09 36.3 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEG14589.1 - 1.2e-13 50.8 0.7 8.2e-10 38.6 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) AAA_33 PF13671.1 KEG14589.1 - 1e-09 38.3 0.4 2.2e-09 37.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain Ank_3 PF13606.1 KEG14589.1 - 2.3e-09 36.5 0.3 0.0002 21.2 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat AAA_17 PF13207.1 KEG14589.1 - 0.00011 23.0 0.0 0.00023 21.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KEG14589.1 - 0.0094 15.1 0.0 0.022 13.9 0.0 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 APS_kinase PF01583.15 KEG14589.1 - 0.012 15.2 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_5 PF07728.9 KEG14589.1 - 0.021 14.5 0.0 0.057 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) His_Phos_1 PF00300.17 KEG14589.1 - 0.088 12.8 0.0 3.2 7.8 0.0 2.4 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Pkinase PF00069.20 KEG14591.1 - 1.2e-58 198.3 0.0 2.8e-38 131.5 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEG14591.1 - 5e-30 104.4 0.0 7.5e-30 103.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG14591.1 - 8.3e-05 21.6 0.0 0.00018 20.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEG14591.1 - 0.033 13.9 0.0 0.079 12.6 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ubiquitin_2 PF14560.1 KEG14592.1 - 3e-11 43.3 0.0 5.4e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain LRR_4 PF12799.2 KEG14592.1 - 3.1e-09 36.2 0.5 0.042 13.4 0.1 4.0 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG14592.1 - 6.2e-06 25.8 5.0 0.16 11.7 0.2 4.1 3 1 0 3 3 3 2 Leucine rich repeat ubiquitin PF00240.18 KEG14592.1 - 0.0018 17.6 0.0 0.0046 16.3 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family LRR_7 PF13504.1 KEG14592.1 - 0.0031 17.4 2.6 2e+02 2.9 0.0 6.3 6 0 0 6 6 6 0 Leucine rich repeat LRR_9 PF14580.1 KEG14592.1 - 0.0054 16.3 0.3 2.2 7.8 0.0 3.7 2 2 1 4 4 4 1 Leucine-rich repeat LRR_1 PF00560.28 KEG14592.1 - 1.1 9.5 7.7 13 6.3 0.0 4.6 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.1 KEG14592.1 - 2.1 8.6 7.9 42 4.6 0.1 5.1 6 0 0 6 6 6 0 Leucine Rich repeat TPR_14 PF13428.1 KEG14595.1 - 2.3e-09 37.0 34.4 0.0014 19.0 0.0 10.6 6 3 3 10 10 9 2 Tetratricopeptide repeat HAT PF02184.11 KEG14595.1 - 2e-06 27.4 15.5 1.6 8.5 0.1 7.2 7 0 0 7 7 7 2 HAT (Half-A-TPR) repeat TPR_16 PF13432.1 KEG14595.1 - 4.5e-06 27.1 29.2 0.078 13.6 0.1 7.5 6 2 1 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.1 KEG14595.1 - 0.00086 19.1 7.8 0.074 12.9 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 KEG14595.1 - 0.0014 18.9 12.5 35 5.1 0.0 7.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.12 KEG14595.1 - 0.012 15.5 3.7 3.3 7.8 0.7 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat SecA_SW PF07516.8 KEG14595.1 - 0.013 15.2 1.0 0.036 13.8 0.7 1.7 1 1 0 1 1 1 0 SecA Wing and Scaffold domain TPR_17 PF13431.1 KEG14595.1 - 0.016 15.4 0.4 19 5.7 0.0 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 KEG14595.1 - 0.027 14.8 7.9 0.89 9.9 0.1 5.2 4 1 0 4 4 4 0 Tetratricopeptide repeat DUF2063 PF09836.4 KEG14595.1 - 0.043 13.7 0.2 0.27 11.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2063) CCP_MauG PF03150.9 KEG14595.1 - 0.044 14.0 2.8 0.91 9.8 0.1 2.9 3 0 0 3 3 3 0 Di-haem cytochrome c peroxidase NRDE-2 PF08424.5 KEG14595.1 - 0.072 11.9 8.6 0.57 8.9 0.2 2.6 3 0 0 3 3 3 0 NRDE-2, necessary for RNA interference Arf PF00025.16 KEG14596.1 - 5e-16 58.4 0.0 1.8e-15 56.6 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family PH PF00169.24 KEG14596.1 - 0.00022 21.3 0.0 0.00095 19.3 0.0 2.1 2 0 0 2 2 2 1 PH domain SRPRB PF09439.5 KEG14596.1 - 0.0013 18.0 0.0 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KEG14596.1 - 0.0027 18.2 0.0 0.0074 16.7 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KEG14596.1 - 0.016 15.1 0.0 0.061 13.2 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase CHAP PF05257.11 KEG14597.1 - 8.4e-11 41.6 0.0 1.5e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 CHAP domain SET PF00856.23 KEG14598.1 - 4.9e-12 46.4 0.0 3.3e-11 43.7 0.0 2.0 1 1 0 1 1 1 1 SET domain C2 PF00168.25 KEG14599.1 - 2.3e-38 129.8 1.2 4.9e-11 42.3 0.0 7.8 8 0 0 8 8 8 7 C2 domain C2 PF00168.25 KEG14600.1 - 2.1e-16 59.5 0.1 1.4e-06 28.0 0.0 4.4 4 0 0 4 4 4 3 C2 domain NT-C2 PF10358.4 KEG14600.1 - 0.002 17.6 0.0 0.081 12.4 0.0 3.1 4 0 0 4 4 4 1 N-terminal C2 in EEIG1 and EHBP1 proteins CEP76-C2 PF15627.1 KEG14600.1 - 0.0068 15.9 0.0 0.75 9.2 0.0 2.5 2 0 0 2 2 2 2 CEP76 C2 domain AAA PF00004.24 KEG14603.1 - 1.2e-43 148.5 0.0 2.6e-43 147.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KEG14603.1 - 3.8e-07 29.9 0.1 1.9e-06 27.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KEG14603.1 - 6.2e-07 29.5 0.4 3.1e-06 27.3 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 KEG14603.1 - 1.8e-06 28.0 0.0 4.2e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KEG14603.1 - 1.7e-05 24.9 0.2 0.00058 19.9 0.2 2.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KEG14603.1 - 2.5e-05 24.1 0.0 0.0037 17.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KEG14603.1 - 2.8e-05 23.2 0.0 7.8e-05 21.8 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KEG14603.1 - 4.2e-05 23.2 0.1 0.00015 21.4 0.1 2.0 2 0 0 2 2 1 1 Part of AAA domain AAA_17 PF13207.1 KEG14603.1 - 0.0002 22.1 0.2 0.00067 20.4 0.0 2.0 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 KEG14603.1 - 0.00034 20.0 0.0 0.00076 18.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 KEG14603.1 - 0.00073 19.4 0.5 0.0035 17.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain KaiC PF06745.8 KEG14603.1 - 0.00085 18.5 0.1 0.067 12.3 0.0 2.6 3 0 0 3 3 3 1 KaiC Zeta_toxin PF06414.7 KEG14603.1 - 0.0032 16.5 0.0 0.01 14.9 0.0 1.8 1 0 0 1 1 1 1 Zeta toxin TIP49 PF06068.8 KEG14603.1 - 0.0034 16.1 0.0 0.01 14.6 0.0 1.8 2 0 0 2 2 2 1 TIP49 C-terminus AAA_28 PF13521.1 KEG14603.1 - 0.0044 17.0 0.8 0.0069 16.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 KEG14603.1 - 0.0047 16.1 0.0 0.013 14.6 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KEG14603.1 - 0.0051 16.4 0.0 0.019 14.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KEG14603.1 - 0.01 15.2 0.5 0.12 11.7 0.1 2.4 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 KEG14603.1 - 0.011 15.1 0.1 0.06 12.8 0.0 2.2 2 1 1 3 3 3 0 Sigma-54 interaction domain RNA_helicase PF00910.17 KEG14603.1 - 0.012 15.7 0.0 0.029 14.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 KEG14603.1 - 0.013 15.8 0.9 0.032 14.5 0.0 2.2 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.8 KEG14603.1 - 0.014 14.2 0.2 0.06 12.2 0.0 2.1 3 0 0 3 3 2 0 Protein of unknown function (DUF815) PhoH PF02562.11 KEG14603.1 - 0.017 14.3 0.0 0.064 12.4 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.1 KEG14603.1 - 0.017 14.6 0.0 0.041 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 KEG14603.1 - 0.025 14.6 0.0 0.11 12.5 0.0 2.2 2 0 0 2 2 1 0 Sigma-54 interaction domain AAA_11 PF13086.1 KEG14603.1 - 0.03 13.8 0.3 0.2 11.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain APG6 PF04111.7 KEG14603.1 - 0.037 13.0 0.1 0.071 12.1 0.1 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Parvo_NS1 PF01057.12 KEG14603.1 - 0.041 12.7 0.0 0.086 11.6 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.7 KEG14603.1 - 0.042 13.5 0.0 0.56 9.8 0.0 2.6 2 1 1 3 3 2 0 NACHT domain DivIC PF04977.10 KEG14603.1 - 0.18 11.3 3.6 0.49 9.9 2.5 1.7 1 0 0 1 1 1 0 Septum formation initiator NTPase_1 PF03266.10 KEG14603.1 - 1.3 8.7 5.4 3.1 7.5 0.0 3.4 3 1 1 4 4 4 0 NTPase HECT PF00632.20 KEG14604.1 - 7.7e-70 235.5 0.0 1.6e-69 234.5 0.0 1.5 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) WWE PF02825.15 KEG14604.1 - 0.12 11.7 0.5 0.28 10.6 0.3 1.5 1 0 0 1 1 1 0 WWE domain AOX PF01786.12 KEG14605.1 - 5e-73 244.9 1.0 7e-73 244.4 0.7 1.2 1 0 0 1 1 1 1 Alternative oxidase Spc97_Spc98 PF04130.8 KEG14606.1 - 3.3e-86 289.7 0.0 4.3e-86 289.3 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family 2HCT PF03390.10 KEG14606.1 - 0.083 11.2 0.0 0.16 10.3 0.0 1.3 1 0 0 1 1 1 0 2-hydroxycarboxylate transporter family Arf PF00025.16 KEG14607.1 - 4.1e-49 166.1 0.1 4.7e-49 165.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KEG14607.1 - 1.4e-13 50.5 0.0 1.7e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.22 KEG14607.1 - 3.6e-10 39.6 0.0 3.6e-08 33.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KEG14607.1 - 4.8e-09 36.1 0.0 7.5e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KEG14607.1 - 4.5e-08 32.5 0.0 6e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KEG14607.1 - 4.6e-08 32.1 1.0 5.6e-06 25.2 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 KEG14607.1 - 5.6e-08 33.3 0.0 8.6e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 KEG14607.1 - 8.3e-07 28.4 1.0 1.9e-05 23.9 0.7 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.7 KEG14607.1 - 1.1e-06 27.9 0.0 1.5e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 KEG14607.1 - 0.00032 20.3 0.0 0.0056 16.2 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein cobW PF02492.14 KEG14607.1 - 0.018 14.5 0.0 2.3 7.6 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 KEG14607.1 - 0.029 14.0 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase PduV-EutP PF10662.4 KEG14607.1 - 0.15 11.5 0.0 3.7 7.0 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF3520 PF12034.3 KEG14608.1 - 0.0016 18.5 1.0 0.0026 17.9 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3520) Dynamitin PF04912.9 KEG14608.1 - 0.02 13.7 0.3 0.022 13.6 0.2 1.1 1 0 0 1 1 1 0 Dynamitin 3Beta_HSD PF01073.14 KEG14608.1 - 0.081 11.6 0.1 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family BBP1_C PF15272.1 KEG14608.1 - 0.55 9.7 3.6 0.94 8.9 1.7 1.9 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal DEAD PF00270.24 KEG14609.1 - 9.6e-34 116.2 0.0 4e-33 114.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEG14609.1 - 1.9e-25 88.5 0.2 6.3e-25 86.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KEG14609.1 - 0.0052 16.9 0.3 36 4.4 0.0 4.0 3 0 0 3 3 3 0 AAA domain Helicase_C_2 PF13307.1 KEG14609.1 - 0.027 14.4 0.0 0.09 12.7 0.0 1.9 1 0 0 1 1 1 0 Helicase C-terminal domain ResIII PF04851.10 KEG14609.1 - 0.97 9.2 7.8 0.3 10.9 0.9 3.2 2 1 0 3 3 3 0 Type III restriction enzyme, res subunit Neuregulin PF02158.10 KEG14611.1 - 0.33 9.6 2.4 0.4 9.4 1.7 1.0 1 0 0 1 1 1 0 Neuregulin family DUF4604 PF15377.1 KEG14611.1 - 0.36 11.0 13.5 0.46 10.6 9.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Ribosomal_L22e PF01776.12 KEG14612.1 - 1.2e-40 137.9 2.6 1.5e-40 137.6 1.8 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF2972 PF11186.3 KEG14612.1 - 0.019 14.8 0.9 0.024 14.5 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) Pkinase PF00069.20 KEG14614.1 - 5.4e-53 179.7 0.0 1e-52 178.8 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG14614.1 - 1.7e-24 86.3 0.1 5.6e-23 81.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEG14614.1 - 0.0011 18.8 0.1 0.0022 17.7 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KEG14614.1 - 0.082 11.6 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase GDI PF00996.13 KEG14615.1 - 3.2e-174 579.3 0.3 3.9e-174 579.1 0.2 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor CALCOCO1 PF07888.6 KEG14616.1 - 0.0058 14.9 12.7 0.011 14.0 8.8 1.5 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4230 PF14014.1 KEG14616.1 - 0.029 14.2 1.1 0.05 13.4 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4230) BLOC1_2 PF10046.4 KEG14616.1 - 0.044 13.9 5.5 0.078 13.1 3.8 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MalF_P2 PF14785.1 KEG14616.1 - 0.16 11.8 2.7 19 5.0 1.8 2.4 1 1 1 2 2 2 0 Maltose transport system permease protein MalF P2 domain AAA_13 PF13166.1 KEG14616.1 - 0.27 9.6 9.6 0.38 9.1 6.7 1.1 1 0 0 1 1 1 0 AAA domain Med9 PF07544.8 KEG14616.1 - 0.35 10.6 6.5 0.065 12.9 0.9 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 TMF_TATA_bd PF12325.3 KEG14616.1 - 0.4 10.4 18.9 0.17 11.5 8.9 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Phlebovirus_NSM PF07246.6 KEG14616.1 - 0.47 9.5 7.7 0.77 8.8 5.3 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M SbcD_C PF12320.3 KEG14616.1 - 1.3 9.1 12.0 0.6 10.1 0.9 2.9 1 1 1 2 2 2 0 Type 5 capsule protein repressor C-terminal domain V_ATPase_I PF01496.14 KEG14616.1 - 1.4 6.7 7.9 1.9 6.2 5.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tropomyosin_1 PF12718.2 KEG14616.1 - 2.7 7.8 24.8 6.8 6.5 17.0 1.7 1 1 0 1 1 1 0 Tropomyosin like Bap31 PF05529.7 KEG14616.1 - 2.9 7.2 6.3 5.7 6.3 4.4 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like GAS PF13851.1 KEG14616.1 - 3.6 6.7 18.3 6.1 5.9 11.7 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Rootletin PF15035.1 KEG14616.1 - 5.5 6.9 25.9 9.6 6.1 15.8 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion UPF0242 PF06785.6 KEG14616.1 - 7.1 5.2 10.9 10 4.6 7.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) PEP-utilisers_N PF05524.8 KEG14616.1 - 9.7 6.0 20.2 1.5 8.6 6.1 3.4 1 1 2 3 3 3 0 PEP-utilising enzyme, N-terminal DTW PF03942.10 KEG14617.1 - 3.8e-14 52.3 0.8 5.8e-14 51.7 0.0 1.6 2 0 0 2 2 2 1 DTW domain DUF4379 PF14311.1 KEG14618.1 - 4.7e-45 151.1 22.1 5e-18 64.6 2.3 3.3 3 0 0 3 3 3 3 Domain of unknown function (DUF4379) zf-MIZ PF02891.15 KEG14618.1 - 0.007 15.8 0.8 0.007 15.8 0.6 4.9 5 1 1 6 6 6 1 MIZ/SP-RING zinc finger SprT-like PF10263.4 KEG14618.1 - 0.048 13.3 9.5 4.5 6.9 0.3 3.4 3 0 0 3 3 3 0 SprT-like family HypA PF01155.14 KEG14618.1 - 0.7 9.5 17.7 1.6 8.4 0.4 3.2 1 1 2 3 3 3 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 KEG14618.1 - 0.82 9.6 21.8 2.1 8.3 1.7 4.1 3 2 1 4 4 4 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.6 KEG14618.1 - 0.9 9.2 16.8 3.8 7.2 0.4 4.7 3 2 0 4 4 4 0 Putative transposase DNA-binding domain zf-TRAF PF02176.13 KEG14619.1 - 0.0012 19.2 11.4 0.0029 17.9 0.5 3.0 2 1 1 3 3 3 2 TRAF-type zinc finger PyrI_C PF02748.10 KEG14619.1 - 0.014 14.8 0.6 0.51 9.8 0.0 2.9 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2 PF00096.21 KEG14619.1 - 0.015 15.6 0.3 0.015 15.6 0.2 4.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type zinc_ribbon_5 PF13719.1 KEG14619.1 - 0.086 12.4 1.0 15 5.3 0.0 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KEG14619.1 - 0.26 11.0 2.7 15 5.4 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_4 PF13894.1 KEG14619.1 - 5.5 7.5 11.4 11 6.5 0.1 4.4 4 1 0 4 4 4 0 C2H2-type zinc finger Dynamin_M PF01031.15 KEG14621.1 - 1.4e-89 299.7 1.4 1.5e-89 299.7 0.1 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 KEG14621.1 - 1e-49 168.5 0.1 4.3e-49 166.5 0.0 2.1 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 KEG14621.1 - 5.4e-23 80.7 1.5 2.5e-22 78.5 1.0 2.2 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KEG14621.1 - 8.7e-06 25.6 0.1 3.9e-05 23.5 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KEG14621.1 - 0.015 15.7 0.0 0.037 14.5 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 KEG14621.1 - 0.039 13.4 0.1 0.12 11.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Med14 PF08638.6 KEG14621.1 - 0.049 12.8 0.3 0.25 10.5 0.0 2.2 2 0 0 2 2 2 0 Mediator complex subunit MED14 LRR_9 PF14580.1 KEG14622.1 - 2.9e-14 53.0 0.3 4.5e-14 52.3 0.2 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 KEG14622.1 - 8.4e-12 44.4 0.4 1.5e-07 30.8 0.3 2.8 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG14622.1 - 1.7e-07 30.8 1.6 1e-06 28.3 1.1 2.2 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.28 KEG14622.1 - 0.007 16.2 4.8 7.6 6.9 0.1 4.3 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.1 KEG14622.1 - 0.15 12.2 4.9 1.4 9.2 0.2 3.7 2 1 1 3 3 3 0 Leucine Rich repeat NAD_Gly3P_dh_N PF01210.18 KEG14623.1 - 1.5e-06 28.0 0.0 1.3e-05 25.0 0.0 2.3 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 KEG14623.1 - 0.0034 16.8 0.0 0.0058 16.0 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_C PF07479.9 KEG14623.1 - 0.016 14.9 0.0 0.04 13.6 0.0 1.7 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Peptidase_M1 PF01433.15 KEG14624.1 - 1.2e-85 287.9 0.0 1.6e-85 287.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 KEG14624.1 - 7.7e-12 45.3 0.0 2.1e-11 43.9 0.0 1.8 1 1 0 1 1 1 1 Peptidase MA superfamily ERAP1_C PF11838.3 KEG14624.1 - 9.8e-11 41.4 0.0 1.6e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.15 KEG14625.1 - 5e-05 22.5 0.1 5.5e-05 22.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M1 Troponin PF00992.15 KEG14626.1 - 0.0062 16.5 2.1 0.0062 16.5 1.4 3.1 3 0 0 3 3 3 1 Troponin DUF972 PF06156.8 KEG14626.1 - 0.25 11.6 20.5 0.057 13.7 1.3 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF972) IncA PF04156.9 KEG14626.1 - 0.69 9.4 24.6 0.18 11.4 1.3 3.5 3 0 0 3 3 3 0 IncA protein Sld5 PF05916.6 KEG14627.1 - 5.9e-06 26.5 0.0 1.1e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein DUF2924 PF11149.3 KEG14628.1 - 0.019 15.0 0.0 4.7 7.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2924) Acyltransferase PF01553.16 KEG14629.1 - 2.2e-13 49.7 0.0 3.3e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase SARA PF11409.3 KEG14630.1 - 0.06 13.2 3.7 0.31 10.9 2.6 2.3 1 0 0 1 1 1 0 Smad anchor for receptor activation (SARA) UCH PF00443.24 KEG14631.1 - 1e-51 175.6 0.0 1.5e-51 175.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEG14631.1 - 3.7e-25 88.9 0.0 6.8e-25 88.1 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KEG14631.1 - 1.2e-15 57.3 3.7 1.2e-15 57.3 2.6 3.5 4 0 0 4 4 4 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 KEG14631.1 - 2.9e-07 30.1 1.1 6e-07 29.1 0.3 2.0 2 0 0 2 2 2 1 UBA/TS-N domain ECH PF00378.15 KEG14632.1 - 3.5e-74 249.0 2.9 3.9e-74 248.8 2.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 KEG14632.1 - 8.1e-05 22.4 0.3 0.032 13.9 0.0 2.3 2 0 0 2 2 2 2 Peptidase family S49 Chordopox_G2 PF05796.7 KEG14632.1 - 0.046 12.8 0.0 0.11 11.5 0.0 1.6 2 0 0 2 2 2 0 Chordopoxvirus protein G2 SDH_sah PF01972.11 KEG14632.1 - 0.049 12.4 0.0 0.078 11.7 0.0 1.3 1 0 0 1 1 1 0 Serine dehydrogenase proteinase ECH_C PF13766.1 KEG14632.1 - 0.055 13.6 0.2 0.09 12.9 0.1 1.4 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region Pkinase PF00069.20 KEG14633.1 - 2e-52 177.9 0.0 2.6e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG14633.1 - 8.8e-33 113.4 0.0 1.3e-32 112.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG14633.1 - 8.5e-05 21.6 0.0 0.00017 20.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEG14633.1 - 0.00042 20.1 0.0 0.13 12.0 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KEG14633.1 - 0.11 11.2 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 KEG14633.1 - 0.16 10.6 0.0 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase NAP PF00956.13 KEG14636.1 - 4.5e-12 45.6 0.1 2.8e-10 39.7 0.0 2.0 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) COQ7 PF03232.8 KEG14637.1 - 1.5e-62 210.1 1.9 1.7e-62 209.8 1.3 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 PTH2 PF01981.11 KEG14637.1 - 0.045 13.4 0.2 0.092 12.4 0.2 1.5 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 DUF2285 PF10074.4 KEG14639.1 - 0.061 13.6 0.8 0.92 9.8 0.4 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2285) AAA_22 PF13401.1 KEG14640.1 - 8.4e-05 22.7 0.1 0.00036 20.6 0.0 2.1 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KEG14640.1 - 0.00021 21.3 0.5 0.0006 19.8 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 KEG14640.1 - 0.0022 17.7 0.1 0.048 13.3 0.1 2.7 1 1 0 1 1 1 1 NACHT domain DUF87 PF01935.12 KEG14640.1 - 0.0045 16.8 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function DUF87 T2SE PF00437.15 KEG14640.1 - 0.0049 15.8 0.0 0.0076 15.1 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.1 KEG14640.1 - 0.012 15.5 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KEG14640.1 - 0.016 15.5 0.0 0.044 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KEG14640.1 - 0.017 14.5 0.4 0.66 9.3 0.1 2.6 1 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KEG14640.1 - 0.037 13.7 0.1 0.095 12.4 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA PF00004.24 KEG14640.1 - 0.045 13.9 0.0 0.091 12.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 KEG14640.1 - 0.048 13.0 0.0 0.087 12.2 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain cobW PF02492.14 KEG14640.1 - 0.051 13.0 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.17 KEG14640.1 - 0.056 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATP-synt_ab PF00006.20 KEG14640.1 - 0.066 12.7 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Bac_DnaA PF00308.13 KEG14640.1 - 0.081 12.5 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_24 PF13479.1 KEG14640.1 - 0.084 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 KEG14640.1 - 0.09 11.5 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 ArgK protein FtsK_SpoIIIE PF01580.13 KEG14640.1 - 0.099 12.1 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family UPF0079 PF02367.12 KEG14640.1 - 0.12 12.0 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 KEG14640.1 - 0.13 11.8 2.8 20 4.6 0.0 3.4 4 0 0 4 4 4 0 AAA domain DUF814 PF05670.8 KEG14641.1 - 2.5e-23 81.7 1.4 1.1e-22 79.7 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF814) DUF2215 PF10225.4 KEG14641.1 - 0.56 9.6 2.1 0.73 9.2 1.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Mgr1 PF08602.5 KEG14641.1 - 0.69 8.8 0.0 0.69 8.8 0.0 2.0 1 1 1 2 2 2 0 Mgr1-like, i-AAA protease complex subunit Prog_receptor PF02161.10 KEG14641.1 - 2.7 6.7 4.5 3.3 6.4 3.2 1.0 1 0 0 1 1 1 0 Progesterone receptor GKAP PF03359.8 KEG14642.1 - 3 7.3 6.0 0.6 9.6 0.4 2.1 1 1 1 2 2 2 0 Guanylate-kinase-associated protein (GKAP) protein Cytochrom_B561 PF03188.11 KEG14643.1 - 9.7e-06 25.4 9.8 9.7e-06 25.4 6.8 2.1 2 1 0 2 2 2 1 Eukaryotic cytochrome b561 Peptidase_C2 PF00648.16 KEG14644.1 - 1.3e-31 109.6 1.2 2.9e-15 56.0 0.0 2.2 2 0 0 2 2 2 2 Calpain family cysteine protease Calpain_III PF01067.17 KEG14644.1 - 1e-13 51.1 0.0 2.3e-12 46.7 0.0 2.7 3 0 0 3 3 3 1 Calpain large subunit, domain III LRR_6 PF13516.1 KEG14644.1 - 0.24 11.5 1.7 24 5.4 0.1 3.1 2 0 0 2 2 2 0 Leucine Rich repeat Mannosyl_trans PF05007.8 KEG14646.1 - 1.4e-88 296.9 16.2 1.9e-88 296.4 11.2 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 KEG14646.1 - 3.1e-09 36.2 22.1 3.1e-09 36.2 15.3 1.5 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U IFT20 PF14931.1 KEG14647.1 - 1.1e-38 131.8 10.8 1.2e-38 131.7 7.5 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 DUF1246 PF06849.7 KEG14647.1 - 0.029 14.1 0.2 0.05 13.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1246) DUF3552 PF12072.3 KEG14647.1 - 0.07 12.3 9.3 0.086 12.0 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) 4HB_MCP_1 PF12729.2 KEG14647.1 - 0.68 9.2 6.7 1.1 8.6 4.0 1.7 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction AAA_23 PF13476.1 KEG14647.1 - 1.9 8.7 5.6 2.2 8.5 3.9 1.1 1 0 0 1 1 1 0 AAA domain Fib_alpha PF08702.5 KEG14647.1 - 3.2 7.8 6.5 4.1 7.5 4.5 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family PC_rep PF01851.17 KEG14648.1 - 0.0065 16.6 14.1 4 7.8 0.2 6.0 6 0 0 6 6 6 2 Proteasome/cyclosome repeat Dapper PF15268.1 KEG14648.1 - 0.11 11.2 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Dapper zf-C2H2_2 PF12756.2 KEG14651.1 - 6.5e-15 55.0 3.6 1.4e-10 41.1 0.2 2.3 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 KEG14651.1 - 1.7 9.1 6.0 1.8 9.0 0.2 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type Syntaxin-6_N PF09177.6 KEG14653.1 - 0.0055 17.0 3.6 0.0055 17.0 2.5 3.0 3 0 0 3 3 3 1 Syntaxin 6, N-terminal DUF3349 PF11829.3 KEG14653.1 - 0.04 14.3 3.8 0.041 14.3 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) DUF4140 PF13600.1 KEG14653.1 - 6.4 7.2 23.6 0.37 11.2 2.1 4.9 4 1 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) Mod_r PF07200.8 KEG14653.1 - 9.5 6.1 18.8 0.12 12.2 3.0 3.6 3 1 1 4 4 4 0 Modifier of rudimentary (Mod(r)) protein PseudoU_synth_2 PF00849.17 KEG14654.1 - 4.4e-19 68.9 0.0 1.5e-09 37.8 0.0 2.5 2 1 0 2 2 2 2 RNA pseudouridylate synthase Med3 PF11593.3 KEG14654.1 - 0.24 10.5 2.8 0.33 10.1 1.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2740 PF10872.3 KEG14655.1 - 0.0087 15.6 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2740) AAA_18 PF13238.1 KEG14657.1 - 7.5e-27 94.1 0.4 9.5e-27 93.8 0.3 1.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEG14657.1 - 1e-13 52.1 0.2 1.4e-13 51.7 0.2 1.3 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KEG14657.1 - 3.4e-05 24.0 0.0 6.5e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KEG14657.1 - 5.2e-05 23.1 0.3 0.0034 17.2 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KEG14657.1 - 0.00018 21.4 1.8 0.00049 20.0 0.2 2.1 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 KEG14657.1 - 0.00028 20.9 0.0 0.00042 20.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.17 KEG14657.1 - 0.0014 18.7 0.0 0.0023 18.0 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.1 KEG14657.1 - 0.0015 18.6 0.0 0.0031 17.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KEG14657.1 - 0.0021 17.2 0.0 0.0035 16.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin DUF2075 PF09848.4 KEG14657.1 - 0.0023 16.9 0.0 0.0032 16.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.9 KEG14657.1 - 0.0032 17.2 0.6 0.03 14.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KEG14657.1 - 0.0044 16.0 0.0 0.0065 15.5 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 KEG14657.1 - 0.0046 16.5 0.1 0.0082 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEG14657.1 - 0.0051 16.5 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain NTPase_1 PF03266.10 KEG14657.1 - 0.006 16.3 0.0 0.0095 15.6 0.0 1.5 1 0 0 1 1 1 1 NTPase KTI12 PF08433.5 KEG14657.1 - 0.0061 15.7 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 ABC_tran PF00005.22 KEG14657.1 - 0.0071 16.6 0.1 0.013 15.8 0.1 1.7 1 1 0 1 1 1 1 ABC transporter Arch_ATPase PF01637.13 KEG14657.1 - 0.0092 15.7 0.2 0.028 14.1 0.1 1.7 1 1 1 2 2 2 1 Archaeal ATPase KAP_NTPase PF07693.9 KEG14657.1 - 0.014 14.4 0.0 0.014 14.4 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain KaiC PF06745.8 KEG14657.1 - 0.019 14.0 0.1 0.034 13.2 0.1 1.3 1 0 0 1 1 1 0 KaiC ADK PF00406.17 KEG14657.1 - 0.022 14.6 0.0 0.37 10.6 0.0 2.1 2 0 0 2 2 2 0 Adenylate kinase IstB_IS21 PF01695.12 KEG14657.1 - 0.022 14.2 0.1 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein T2SE PF00437.15 KEG14657.1 - 0.022 13.6 0.1 0.035 13.0 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Mg_chelatase PF01078.16 KEG14657.1 - 0.029 13.5 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MobB PF03205.9 KEG14657.1 - 0.03 14.0 0.1 0.064 12.9 0.1 1.6 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Sigma54_activat PF00158.21 KEG14657.1 - 0.034 13.6 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain TIP49 PF06068.8 KEG14657.1 - 0.037 12.7 0.0 0.078 11.6 0.0 1.5 2 0 0 2 2 2 0 TIP49 C-terminus SKI PF01202.17 KEG14657.1 - 0.039 13.8 0.7 0.22 11.4 0.5 2.0 1 1 0 1 1 1 0 Shikimate kinase AAA_14 PF13173.1 KEG14657.1 - 0.04 13.8 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 KEG14657.1 - 0.05 12.4 0.0 0.081 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 cobW PF02492.14 KEG14657.1 - 0.06 12.7 0.0 0.089 12.2 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 KEG14657.1 - 0.082 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain TrwB_AAD_bind PF10412.4 KEG14657.1 - 0.085 11.4 0.0 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Thymidylate_kin PF02223.12 KEG14657.1 - 0.089 12.1 0.8 1.5 8.1 0.1 2.3 2 1 1 3 3 3 0 Thymidylate kinase DUF815 PF05673.8 KEG14657.1 - 0.091 11.6 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_10 PF12846.2 KEG14657.1 - 0.099 12.0 0.0 0.099 12.0 0.0 1.4 1 1 0 1 1 1 0 AAA-like domain APS_kinase PF01583.15 KEG14657.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase CPT PF07931.7 KEG14657.1 - 0.11 12.0 0.3 0.35 10.4 0.2 2.1 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Torsin PF06309.6 KEG14657.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Torsin Miro PF08477.8 KEG14657.1 - 0.13 12.7 0.0 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein DUF3505 PF12013.3 KEG14658.1 - 0.034 14.3 0.9 0.04 14.1 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) Fer2 PF00111.22 KEG14658.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain RolB_RolC PF02027.12 KEG14660.1 - 0.0043 16.2 3.5 0.46 9.6 0.8 2.3 2 0 0 2 2 2 2 RolB/RolC glucosidase family FAM178 PF14816.1 KEG14660.1 - 5.5 5.5 12.1 6.5 5.3 3.0 2.2 2 0 0 2 2 2 0 Family of unknown function, FAM178 Macoilin PF09726.4 KEG14661.1 - 0.15 10.2 5.7 0.23 9.7 3.9 1.2 1 0 0 1 1 1 0 Transmembrane protein CDC45 PF02724.9 KEG14661.1 - 8.3 4.3 9.5 12 3.7 6.6 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF3449 PF11931.3 KEG14662.1 - 6.7e-43 146.5 0.5 1.1e-42 145.7 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) HMG_box PF00505.14 KEG14663.1 - 0.055 13.7 3.6 0.072 13.3 0.0 2.9 2 1 1 3 3 3 0 HMG (high mobility group) box Glyco_hydro_42 PF02449.10 KEG14663.1 - 0.095 11.8 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Beta-galactosidase DUF3106 PF11304.3 KEG14663.1 - 1.2 9.5 11.3 2.1 8.7 5.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3106) Maelstrom PF13017.1 KEG14664.1 - 0.0019 17.7 0.3 0.0041 16.6 0.2 1.5 1 1 0 1 1 1 1 piRNA pathway germ-plasm component PRKCSH_1 PF13015.1 KEG14664.1 - 0.13 11.7 2.8 0.22 11.0 0.1 2.2 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein Taxilin PF09728.4 KEG14665.1 - 5.8e-12 45.3 39.0 7.6e-12 44.9 27.1 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein DUF1948 PF09185.5 KEG14665.1 - 0.012 15.3 3.3 0.014 15.0 1.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1948) Reo_sigmaC PF04582.7 KEG14665.1 - 0.36 9.9 6.7 0.81 8.8 0.3 2.3 1 1 0 2 2 2 0 Reovirus sigma C capsid protein Mnd1 PF03962.10 KEG14665.1 - 2.3 7.8 41.1 0.25 10.9 7.7 3.1 1 1 2 3 3 3 0 Mnd1 family NPV_P10 PF05531.7 KEG14665.1 - 4 7.7 8.0 14 6.0 0.1 3.8 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF4064 PF13273.1 KEG14666.1 - 0.59 10.2 7.6 0.2 11.7 1.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) LmjF365940-deam PF14421.1 KEG14667.1 - 1.2e-41 142.2 0.0 5.1e-20 71.6 0.0 2.3 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases zf-CCCH_2 PF14608.1 KEG14667.1 - 0.018 14.9 0.1 0.076 13.0 0.1 2.2 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type MMPL PF03176.10 KEG14668.1 - 3.6e-57 193.5 16.6 2.9e-33 114.9 1.7 2.4 2 0 0 2 2 2 2 MMPL family Tmemb_185A PF10269.4 KEG14670.1 - 4.3e-05 23.2 22.6 0.024 14.2 1.3 3.1 1 1 1 3 3 3 3 Transmembrane Fragile-X-F protein SpoV PF08183.6 KEG14671.1 - 8.9e-06 25.2 0.0 2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Stage V sporulation protein family Baculo_PEP_C PF04513.7 KEG14672.1 - 0.0011 18.7 4.8 0.064 13.0 0.0 4.7 5 1 1 6 6 6 1 Baculovirus polyhedron envelope protein, PEP, C terminus OTU PF02338.14 KEG14674.1 - 5.3e-13 49.6 0.0 8e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease YrpD PF15493.1 KEG14675.1 - 0.12 12.0 0.1 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function, YrpD YHS PF04945.8 KEG14677.1 - 3.2e-13 49.2 1.1 0.00065 19.4 0.0 4.5 4 0 0 4 4 4 3 YHS domain AAA_17 PF13207.1 KEG14677.1 - 4.7e-09 37.1 15.3 6.1e-08 33.5 0.1 4.5 4 2 0 4 4 2 2 AAA domain ADK PF00406.17 KEG14677.1 - 5.2e-07 29.6 0.7 0.00022 21.1 0.6 3.6 2 1 0 2 2 2 1 Adenylate kinase AAA_33 PF13671.1 KEG14677.1 - 0.00035 20.4 0.0 0.75 9.6 0.0 3.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KEG14677.1 - 0.004 17.4 0.0 0.004 17.4 0.0 5.5 5 2 0 5 5 4 1 AAA domain AAA PF00004.24 KEG14677.1 - 0.019 15.1 0.0 0.21 11.8 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEG14677.1 - 0.022 14.7 14.1 0.14 12.1 0.0 5.4 5 0 0 5 5 5 0 AAA ATPase domain AAA_14 PF13173.1 KEG14677.1 - 0.087 12.7 0.0 1.8 8.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KEG14677.1 - 0.097 12.8 0.0 0.45 10.6 0.0 2.2 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 KEG14677.1 - 0.12 12.0 0.0 14 5.4 0.0 3.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KEG14677.1 - 0.2 11.8 0.1 2 8.6 0.0 2.7 3 0 0 3 3 3 0 RNA helicase DUF3508 PF12018.3 KEG14677.1 - 0.21 10.5 13.1 0.41 9.5 0.1 4.6 5 0 0 5 5 5 0 Domain of unknown function (DUF3508) RabGAP-TBC PF00566.13 KEG14678.1 - 8.6e-58 195.3 0.0 1.1e-57 194.9 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RabGAP-TBC PF00566.13 KEG14680.1 - 8.1e-54 182.3 0.1 1e-53 181.9 0.1 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain TPR_16 PF13432.1 KEG14681.1 - 0.0011 19.6 0.1 0.0053 17.4 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 KEG14681.1 - 0.0076 15.8 0.1 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 TPR repeat ABC1 PF03109.11 KEG14682.1 - 4.7e-27 94.3 0.0 7.8e-27 93.6 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.20 KEG14682.1 - 6.3e-07 28.8 0.8 1.3e-05 24.4 0.5 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG14682.1 - 1.5e-06 27.4 0.1 0.0064 15.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KEG14682.1 - 3.3e-06 26.9 1.2 7.4e-06 25.8 0.3 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KEG14682.1 - 0.0017 17.7 0.0 0.0034 16.7 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KEG14682.1 - 0.013 14.5 0.1 0.025 13.6 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4500 PF14937.1 KEG14682.1 - 0.096 12.5 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) TPR_19 PF14559.1 KEG14683.1 - 5e-06 26.7 5.9 1.1 9.6 0.0 5.9 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEG14683.1 - 1.8e-05 24.9 9.3 0.16 12.7 0.0 6.6 6 2 1 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.1 KEG14683.1 - 4.9e-05 22.8 7.5 0.0075 15.8 0.0 4.8 5 1 0 5 5 5 2 TPR repeat Apc3 PF12895.2 KEG14683.1 - 7.5e-05 22.7 0.4 4.9 7.3 0.0 4.6 4 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KEG14683.1 - 8.1e-05 22.4 8.1 6.9 6.6 0.0 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEG14683.1 - 0.00014 21.5 4.0 0.11 12.4 0.0 5.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEG14683.1 - 0.003 17.0 0.3 0.17 11.5 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEG14683.1 - 0.053 14.2 8.9 6.4 7.5 0.1 5.3 6 1 0 6 6 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEG14683.1 - 0.19 12.2 6.3 29 5.4 0.0 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 KEG14683.1 - 0.21 12.1 13.5 3.4 8.3 1.8 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat PPR_3 PF13812.1 KEG14683.1 - 0.68 10.3 5.1 1.6 9.2 0.0 4.1 6 0 0 6 6 3 0 Pentatricopeptide repeat domain EF-hand_7 PF13499.1 KEG14684.1 - 2.1e-14 53.3 0.1 2.6e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KEG14684.1 - 2.9e-10 39.1 0.0 0.0014 18.3 0.0 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.27 KEG14684.1 - 3e-09 35.4 0.7 0.0028 16.8 0.0 4.7 5 1 0 5 5 5 2 EF hand EF-hand_8 PF13833.1 KEG14684.1 - 4.6e-09 35.7 0.9 7.6e-07 28.6 0.2 2.7 2 1 1 3 3 3 1 EF-hand domain pair EFhand_Ca_insen PF08726.5 KEG14684.1 - 0.00079 19.3 0.1 0.71 9.8 0.0 2.4 2 0 0 2 2 2 2 Ca2+ insensitive EF hand EF-hand_5 PF13202.1 KEG14684.1 - 0.0022 17.2 0.1 0.36 10.2 0.0 3.4 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.1 KEG14684.1 - 0.11 12.4 0.1 4.2 7.3 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain RNA_pol_Rpc34 PF05158.7 KEG14685.1 - 2e-58 198.1 0.0 2.4e-58 197.9 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit HTH_27 PF13463.1 KEG14685.1 - 2.2e-05 24.7 0.2 0.011 15.9 0.1 2.4 2 0 0 2 2 2 2 Winged helix DNA-binding domain MarR_2 PF12802.2 KEG14685.1 - 0.00021 20.8 6.1 0.024 14.2 0.5 2.8 3 0 0 3 3 3 2 MarR family HTH_20 PF12840.2 KEG14685.1 - 0.00058 19.6 1.8 0.29 10.9 0.4 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain RPA_C PF08784.6 KEG14685.1 - 0.0011 19.3 0.1 3.7 8.0 0.0 3.0 3 0 0 3 3 3 2 Replication protein A C terminal TrmB PF01978.14 KEG14685.1 - 0.0025 17.5 0.1 0.082 12.6 0.0 2.5 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB HTH_32 PF13565.1 KEG14685.1 - 0.024 15.4 0.1 0.065 14.0 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_36 PF13730.1 KEG14685.1 - 0.035 14.2 0.0 2.3 8.4 0.0 2.7 2 1 0 2 2 2 0 Helix-turn-helix domain FeoC PF09012.5 KEG14685.1 - 0.083 12.6 0.3 0.97 9.1 0.1 2.2 2 0 0 2 2 2 0 FeoC like transcriptional regulator z-alpha PF02295.12 KEG14685.1 - 0.12 12.1 0.0 4.6 7.0 0.0 2.4 2 1 0 2 2 2 0 Adenosine deaminase z-alpha domain Rrf2 PF02082.15 KEG14685.1 - 0.99 9.5 3.1 3.2 7.9 0.1 2.6 3 0 0 3 3 3 0 Transcriptional regulator Carn_acyltransf PF00755.15 KEG14686.1 - 2e-119 399.3 0.0 2.2e-119 399.2 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DSS1_SEM1 PF05160.8 KEG14688.1 - 0.0016 18.2 3.3 0.0016 18.2 2.3 2.1 2 0 0 2 2 2 1 DSS1/SEM1 family Lipase_3 PF01764.20 KEG14689.1 - 1.2e-29 102.7 0.0 3e-29 101.4 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 3) DUF2974 PF11187.3 KEG14689.1 - 0.0027 17.1 0.0 0.032 13.6 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Lipase_3 PF01764.20 KEG14691.1 - 8.3e-26 90.2 0.0 2e-25 89.0 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 KEG14691.1 - 0.017 14.5 0.0 0.076 12.3 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Sec16_C PF12931.2 KEG14692.1 - 1.2e-15 58.0 0.0 2.1e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 DUF572 PF04502.8 KEG14693.1 - 2.6e-21 76.1 13.0 3.4e-21 75.8 9.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-BED PF02892.10 KEG14693.1 - 0.73 9.6 5.0 1.6 8.5 0.1 3.0 3 0 0 3 3 3 0 BED zinc finger Zn_Tnp_IS1595 PF12760.2 KEG14693.1 - 4.4 7.1 10.7 0.56 10.0 0.8 3.1 3 0 0 3 3 3 0 Transposase zinc-ribbon domain Metallophos PF00149.23 KEG14696.1 - 2.3e-10 40.2 0.1 0.00061 19.2 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KEG14696.1 - 4.5e-09 36.3 0.0 8.1e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PhoD PF09423.5 KEG14696.1 - 0.081 11.4 0.0 2.1 6.8 0.0 2.1 2 0 0 2 2 2 0 PhoD-like phosphatase LST1 PF05083.8 KEG14696.1 - 0.089 12.7 0.2 0.27 11.2 0.2 1.8 1 0 0 1 1 1 0 LST-1 protein SKG6 PF08693.5 KEG14696.1 - 0.094 12.0 1.9 0.23 10.8 1.3 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EI24 PF07264.6 KEG14697.1 - 5.7e-31 107.6 17.8 1.1e-30 106.7 12.3 1.5 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) VirB3 PF05101.8 KEG14697.1 - 0.13 12.2 0.3 0.13 12.2 0.2 3.5 3 1 1 4 4 4 0 Type IV secretory pathway, VirB3-like protein Thioredoxin_8 PF13905.1 KEG14698.1 - 9.3e-06 25.6 0.0 0.044 13.9 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like Cwf_Cwc_15 PF04889.7 KEG14698.1 - 2.1 8.0 10.5 0.82 9.3 1.6 2.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Thioredoxin_8 PF13905.1 KEG14700.1 - 2e-27 95.1 0.0 2.8e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KEG14700.1 - 3.3e-11 43.3 0.0 4.2e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 KEG14700.1 - 2.1e-10 40.2 0.0 2.6e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KEG14700.1 - 2.4e-09 36.9 0.0 2.9e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.15 KEG14700.1 - 4.2e-09 36.0 0.0 4.5e-06 26.2 0.0 2.1 1 1 0 2 2 2 2 Thioredoxin TraF PF13728.1 KEG14700.1 - 4.9e-07 29.4 0.0 2.4e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.1 KEG14700.1 - 0.00033 20.2 0.0 0.017 14.6 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 KEG14700.1 - 0.00053 19.9 0.0 0.00068 19.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like DUF953 PF06110.6 KEG14700.1 - 0.023 14.1 0.1 0.44 9.9 0.0 2.1 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_8 PF13905.1 KEG14701.1 - 5.9e-20 71.1 0.0 9e-20 70.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 KEG14701.1 - 4.6e-09 35.9 0.0 6e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KEG14701.1 - 1.1e-08 34.7 0.0 1.4e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.1 KEG14701.1 - 1.3e-08 35.0 0.0 2.2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.15 KEG14701.1 - 2e-08 33.8 0.0 1.4e-07 31.1 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_9 PF14595.1 KEG14701.1 - 3.9e-06 26.4 0.0 1.3e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_7 PF13899.1 KEG14701.1 - 1.8e-05 24.6 0.0 0.0001 22.2 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like TraF PF13728.1 KEG14701.1 - 0.048 13.1 0.0 0.07 12.6 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein PSP1 PF04468.7 KEG14702.1 - 8.5e-16 57.7 0.7 1.4e-15 56.9 0.5 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region P12 PF12669.2 KEG14702.1 - 2.1 8.5 28.3 7.3 6.8 2.2 2.5 2 0 0 2 2 2 0 Virus attachment protein p12 family Ank_2 PF12796.2 KEG14704.1 - 9e-32 109.2 1.4 3.8e-10 39.9 0.0 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEG14704.1 - 9.9e-28 96.0 0.4 2.3e-10 40.7 0.0 5.1 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.25 KEG14704.1 - 6.5e-25 85.6 0.2 9e-05 22.0 0.0 7.2 7 1 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.1 KEG14704.1 - 2.4e-21 73.6 2.0 0.0026 17.8 0.0 7.3 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 KEG14704.1 - 1e-17 63.7 1.7 0.00013 22.0 0.0 5.7 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ribosomal_L4 PF00573.17 KEG14705.1 - 1.1e-38 132.5 0.0 1.1e-38 132.5 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 KEG14705.1 - 3e-14 52.6 3.9 3e-14 52.6 2.7 2.0 2 1 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain DSPc PF00782.15 KEG14707.1 - 2e-30 105.0 0.1 2.8e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KEG14707.1 - 0.0001 21.7 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KEG14707.1 - 0.016 15.2 0.4 0.044 13.8 0.0 1.8 2 1 0 2 2 2 0 Inositol hexakisphosphate Init_tRNA_PT PF04179.7 KEG14707.1 - 0.086 11.6 0.0 0.096 11.5 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Nitr_red_assoc PF09655.5 KEG14710.1 - 0.13 12.5 0.4 0.14 12.4 0.3 1.1 1 0 0 1 1 1 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) CEP19 PF14933.1 KEG14711.1 - 3e-28 99.1 0.4 3.3e-28 98.9 0.3 1.0 1 0 0 1 1 1 1 CEP19-like protein CEP19 PF14933.1 KEG14712.1 - 2.2e-07 31.2 0.0 3.2e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 CEP19-like protein Nop PF01798.13 KEG14713.1 - 1.5e-20 73.0 0.1 3.1e-20 72.0 0.0 1.5 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 KEG14713.1 - 9.8e-13 47.7 0.1 2e-12 46.6 0.1 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain Aminotran_1_2 PF00155.16 KEG14713.1 - 0.13 11.2 0.0 0.26 10.2 0.0 1.4 2 0 0 2 2 2 0 Aminotransferase class I and II Tetraspannin PF00335.15 KEG14715.1 - 4e-20 72.0 5.8 5.4e-20 71.6 4.0 1.1 1 0 0 1 1 1 1 Tetraspanin family UPF0182 PF03699.8 KEG14715.1 - 0.0096 13.9 0.7 0.013 13.4 0.5 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0182) Peptidase_C62 PF12380.3 KEG14715.1 - 0.16 10.7 0.1 0.24 10.2 0.1 1.2 1 0 0 1 1 1 0 Gill-associated viral 3C-like peptidase DUF4134 PF13572.1 KEG14715.1 - 0.37 10.9 0.0 0.37 10.9 0.0 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4134) NfeD PF01957.13 KEG14715.1 - 0.4 10.8 10.9 4.6 7.3 3.4 2.4 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding COPI_assoc PF08507.5 KEG14715.1 - 2.5 7.7 6.1 0.6 9.7 1.1 2.0 2 1 1 3 3 3 0 COPI associated protein USP8_interact PF08941.5 KEG14716.1 - 0.021 14.1 0.0 0.043 13.1 0.0 1.5 1 0 0 1 1 1 0 USP8 interacting Lung_7-TM_R PF06814.8 KEG14717.1 - 4.3e-31 107.9 10.6 6.3e-31 107.4 7.4 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor Peptidase_M14 PF00246.19 KEG14719.1 - 1.8e-25 90.1 0.0 3.5e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.9 KEG14719.1 - 0.054 12.3 0.0 0.094 11.5 0.0 1.3 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Metallophos PF00149.23 KEG14721.1 - 6e-18 64.9 1.2 9.1e-18 64.3 0.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KEG14721.1 - 0.00093 19.0 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PhoD PF09423.5 KEG14721.1 - 0.0041 15.7 0.0 0.0064 15.1 0.0 1.3 1 0 0 1 1 1 1 PhoD-like phosphatase DUF1180 PF06679.7 KEG14721.1 - 5.6 6.8 5.8 9.7 6.0 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) HAP2-GCS1 PF10699.4 KEG14722.1 - 3.6e-21 74.8 0.4 8.1e-21 73.7 0.2 1.7 1 0 0 1 1 1 1 Male gamete fusion factor zf-DHHC PF01529.15 KEG14724.1 - 1.1e-38 132.4 3.2 1.1e-38 132.4 2.2 1.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase A_deamin PF02137.13 KEG14727.1 - 1e-37 130.2 0.0 2.5e-37 128.9 0.0 1.6 2 0 0 2 2 2 1 Adenosine-deaminase (editase) domain GST_N_3 PF13417.1 KEG14728.1 - 2e-34 117.6 0.2 5.5e-18 64.9 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KEG14728.1 - 3.4e-25 87.8 0.2 7.1e-15 54.7 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KEG14728.1 - 6.4e-19 67.6 1.0 3.6e-09 36.3 0.0 2.7 3 0 0 3 3 3 2 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KEG14728.1 - 3.2e-12 46.4 0.1 9.2e-09 35.3 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KEG14728.1 - 5.6e-10 39.0 0.2 0.00027 20.8 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KEG14728.1 - 1.2e-09 38.5 0.0 0.00014 22.2 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 KEG14728.1 - 1.3e-07 31.4 0.5 1e-06 28.6 0.1 2.3 2 0 0 2 2 2 1 Glutaredoxin RRM_1 PF00076.17 KEG14730.1 - 6.5e-11 41.7 0.0 9.8e-11 41.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG14730.1 - 1.2e-08 34.7 0.0 2e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG14730.1 - 9.6e-06 25.3 0.0 1.6e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KEG14730.1 - 1.8e-05 24.5 0.3 4.4e-05 23.2 0.1 1.7 1 1 0 1 1 1 1 RNA binding motif Chlorosome_CsmC PF11098.3 KEG14730.1 - 0.011 15.4 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Chlorosome envelope protein C Limkain-b1 PF11608.3 KEG14730.1 - 0.018 14.7 0.0 0.032 13.9 0.0 1.5 1 1 0 1 1 1 0 Limkain b1 NID PF07292.8 KEG14730.1 - 0.092 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Nmi/IFP 35 domain (NID) EIF_2_alpha PF07541.7 KEG14731.1 - 8.3e-25 86.7 0.0 2.8e-24 85.0 0.0 1.9 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 KEG14731.1 - 2e-10 40.6 2.1 2.6e-10 40.2 0.9 1.6 2 0 0 2 2 2 1 S1 RNA binding domain EXOSC1 PF10447.4 KEG14731.1 - 0.0025 17.7 0.8 0.0062 16.4 0.5 1.7 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 Pkinase PF00069.20 KEG14732.1 - 3e-18 65.9 0.0 4.5e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG14732.1 - 0.00011 21.4 0.0 0.0003 19.9 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase MORN PF02493.15 KEG14733.1 - 4.2e-23 79.6 38.9 5.8e-06 25.7 3.3 7.0 7 0 0 7 7 7 6 MORN repeat TFIIIC_sub6 PF10419.4 KEG14733.1 - 6.8 6.2 6.1 33 4.0 0.1 3.7 3 1 1 4 4 4 0 TFIIIC subunit Cu-oxidase_2 PF07731.9 KEG14735.1 - 5.8e-17 61.4 0.5 2.5e-16 59.4 0.2 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 KEG14735.1 - 2e-09 37.1 0.6 4e-05 23.3 0.1 4.0 3 1 0 4 4 4 3 Multicopper oxidase Snapin_Pallidin PF14712.1 KEG14738.1 - 5.2e-06 26.6 1.4 9.8e-06 25.8 1.0 1.4 1 0 0 1 1 1 1 Snapin/Pallidin ADIP PF11559.3 KEG14738.1 - 0.00042 20.2 4.7 0.00056 19.8 3.3 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.7 KEG14738.1 - 0.0011 18.7 1.1 0.0017 18.1 0.8 1.3 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein EspB PF05802.6 KEG14738.1 - 0.017 14.1 2.4 0.057 12.3 0.5 1.9 1 1 1 2 2 2 0 Enterobacterial EspB protein DUF745 PF05335.8 KEG14738.1 - 0.046 13.2 3.0 0.067 12.7 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Siah-Interact_N PF09032.6 KEG14738.1 - 0.077 13.0 3.2 1.4 9.0 0.1 2.2 2 0 0 2 2 2 0 Siah interacting protein, N terminal M_domain PF12938.2 KEG14738.1 - 0.1 12.4 0.4 0.13 12.0 0.2 1.1 1 0 0 1 1 1 0 M domain of GW182 ATG16 PF08614.6 KEG14738.1 - 0.1 12.3 5.0 0.19 11.5 3.5 1.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF972 PF06156.8 KEG14738.1 - 0.13 12.6 4.1 2 8.8 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Nup54 PF13874.1 KEG14738.1 - 0.14 11.8 5.9 0.25 10.9 4.1 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Prominin PF05478.6 KEG14738.1 - 0.15 9.5 1.6 0.18 9.2 1.1 1.0 1 0 0 1 1 1 0 Prominin DUF4200 PF13863.1 KEG14738.1 - 0.18 11.7 4.2 2.2 8.2 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Atg14 PF10186.4 KEG14738.1 - 0.61 8.9 5.8 0.79 8.6 4.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 UPF0449 PF15136.1 KEG14738.1 - 1.7 8.8 5.0 1.2 9.4 1.1 2.0 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 Rootletin PF15035.1 KEG14738.1 - 3.3 7.6 10.9 1.5 8.7 1.1 2.1 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Amidohydro_3 PF07969.6 KEG14739.1 - 1.8e-49 169.0 0.0 5.6e-49 167.4 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 KEG14739.1 - 9.4e-12 45.2 1.0 3.4e-07 30.2 0.2 3.2 2 2 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 KEG14739.1 - 1.9e-06 27.5 0.1 6.4e-06 25.8 0.1 1.9 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 KEG14739.1 - 4.1e-06 27.0 0.8 0.11 12.5 0.0 2.7 2 1 0 2 2 2 2 Amidohydrolase LSM PF01423.17 KEG14740.1 - 6.8e-09 35.1 0.2 1e-08 34.5 0.1 1.3 1 0 0 1 1 1 1 LSM domain Mut7-C PF01927.11 KEG14741.1 - 8.6e-34 116.6 1.0 6.9e-33 113.6 0.7 1.9 1 1 0 1 1 1 1 Mut7-C RNAse domain SUKH_6 PF14568.1 KEG14741.1 - 0.13 12.7 0.0 0.2 12.1 0.0 1.3 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall UQ_con PF00179.21 KEG14742.1 - 8.4e-33 112.7 0.0 1.1e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme S4 PF01479.20 KEG14743.1 - 2.3e-06 26.9 0.1 6.9e-06 25.3 0.0 1.9 2 0 0 2 2 2 1 S4 domain Kinesin PF00225.18 KEG14744.1 - 9.9e-102 340.0 0.1 9.9e-102 340.0 0.1 2.4 2 0 0 2 2 2 1 Kinesin motor domain Trypsin_2 PF13365.1 KEG14745.1 - 0.00037 20.4 0.0 0.00077 19.4 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain EF-hand_6 PF13405.1 KEG14746.1 - 3.6e-12 45.0 1.0 0.0015 18.2 0.0 4.9 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.27 KEG14746.1 - 2.3e-09 35.8 0.3 0.25 10.7 0.0 5.2 5 0 0 5 5 5 2 EF hand EF-hand_7 PF13499.1 KEG14746.1 - 1.1e-08 35.0 0.9 0.011 15.8 0.0 3.3 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.1 KEG14746.1 - 1.2e-08 34.4 2.0 0.21 11.2 0.0 4.5 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.1 KEG14746.1 - 0.07 13.0 0.0 0.34 10.8 0.0 2.2 3 0 0 3 3 3 0 EF-hand domain EFhand_Ca_insen PF08726.5 KEG14746.1 - 0.13 12.2 0.0 10 6.1 0.0 2.5 2 0 0 2 2 2 0 Ca2+ insensitive EF hand EF-hand_5 PF13202.1 KEG14746.1 - 0.37 10.2 3.7 25 4.4 0.0 4.5 5 0 0 5 5 5 0 EF hand AKAP7_NLS PF10469.4 KEG14747.1 - 1.3e-39 136.1 0.0 1.5e-39 135.8 0.0 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.1 KEG14747.1 - 3.4e-10 39.8 0.0 4.7e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.11 KEG14747.1 - 0.001 19.0 0.0 0.082 12.8 0.0 2.4 2 0 0 2 2 2 1 LigT like Phosphoesterase DUF3996 PF13161.1 KEG14747.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3996) DSPc PF00782.15 KEG14748.1 - 8.8e-15 54.4 0.0 1.9e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KEG14748.1 - 4.8e-14 52.2 0.1 1.4e-13 50.7 0.0 1.7 1 1 1 2 2 2 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 KEG14748.1 - 7e-06 25.5 0.0 1.4e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 KEG14748.1 - 8.7e-06 25.8 0.0 5.2e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 KEG14748.1 - 0.00047 20.4 0.0 0.00095 19.4 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family AMMECR1 PF01871.12 KEG14749.1 - 3.4e-50 169.4 0.0 4.3e-50 169.1 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 MgtE PF01769.11 KEG14750.1 - 8.1e-13 48.8 2.1 8.1e-13 48.8 1.5 1.8 2 0 0 2 2 2 1 Divalent cation transporter DUF2085 PF09858.4 KEG14750.1 - 0.086 12.9 0.5 0.086 12.9 0.4 2.3 2 1 0 2 2 2 0 Predicted membrane protein (DUF2085) ABC2_membrane_5 PF13346.1 KEG14750.1 - 1.7 7.9 18.2 0.45 9.7 8.5 2.3 2 1 0 2 2 2 0 ABC-2 family transporter protein WD40 PF00400.27 KEG14752.1 - 3.6e-15 55.1 13.6 8.1e-05 22.3 0.3 5.7 5 1 0 5 5 5 4 WD domain, G-beta repeat Rota_NSP4 PF01452.11 KEG14753.1 - 0.093 12.0 0.1 13 5.0 0.0 2.4 2 0 0 2 2 2 0 Rotavirus non structural protein DnaJ PF00226.26 KEG14754.1 - 1e-09 37.9 0.0 2.3e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Toxin_52 PF15605.1 KEG14754.1 - 0.0033 17.2 0.2 0.0076 16.1 0.0 1.7 2 0 0 2 2 2 1 Putative toxin 52 Acetyltransf_11 PF13720.1 KEG14754.1 - 0.022 14.9 1.1 0.26 11.5 0.1 2.6 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Folliculin PF11704.3 KEG14754.1 - 0.097 12.2 2.3 0.12 11.9 0.2 2.0 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport CoatB PF10389.4 KEG14754.1 - 1.4 8.8 5.5 3 7.7 3.8 1.4 1 0 0 1 1 1 0 Bacteriophage coat protein B DUF3106 PF11304.3 KEG14754.1 - 6.5 7.2 10.5 11 6.5 1.2 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF3106) BNR_3 PF13859.1 KEG14755.1 - 0.082 11.9 0.5 0.2 10.6 0.4 1.6 1 1 1 2 2 2 0 BNR repeat-like domain DEAD PF00270.24 KEG14756.1 - 1.4e-33 115.8 0.2 4.1e-33 114.2 0.0 1.9 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEG14756.1 - 6.5e-26 90.0 0.2 5.5e-25 87.0 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEG14756.1 - 2.5e-06 27.4 0.0 7.3e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 KEG14756.1 - 0.0031 17.4 0.0 0.0093 15.9 0.0 1.9 1 0 0 1 1 1 1 Helicase C-terminal domain SNF2_N PF00176.18 KEG14756.1 - 0.0079 15.0 0.0 0.016 13.9 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain CHCH PF06747.8 KEG14757.1 - 4e-06 26.6 10.4 0.0059 16.4 0.2 3.5 4 0 0 4 4 4 3 CHCH domain DUF1903 PF08991.5 KEG14757.1 - 0.002 18.2 7.2 0.005 16.9 0.4 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF1903) Cmc1 PF08583.5 KEG14757.1 - 0.28 10.9 4.3 1.2 8.9 0.8 2.5 2 1 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 KEG14757.1 - 1.6 8.8 7.2 0.75 9.8 0.6 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 TauE PF01925.14 KEG14758.1 - 1.4e-17 63.9 27.9 3.4e-15 56.1 19.3 2.2 1 1 0 1 1 1 1 Sulfite exporter TauE/SafE Profilin PF00235.14 KEG14760.1 - 1.5e-35 121.9 0.2 1.8e-35 121.6 0.1 1.1 1 0 0 1 1 1 1 Profilin CDC50 PF03381.10 KEG14761.1 - 4.3e-71 239.3 0.0 5.5e-71 238.9 0.0 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Ras PF00071.17 KEG14763.1 - 6.3e-58 194.7 0.1 7.6e-58 194.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEG14763.1 - 2.3e-23 82.9 0.0 3.4e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEG14763.1 - 5e-15 55.1 0.0 6.1e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KEG14763.1 - 6.3e-06 25.4 0.1 1.5e-05 24.2 0.0 1.6 1 1 1 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KEG14763.1 - 1.2e-05 25.2 0.0 1.8e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KEG14763.1 - 4e-05 23.1 0.0 0.00022 20.7 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KEG14763.1 - 0.00096 19.2 0.0 0.0032 17.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEG14763.1 - 0.001 19.1 0.1 0.0013 18.7 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain YwhD PF08741.5 KEG14763.1 - 0.0038 16.6 0.0 0.0065 15.8 0.0 1.5 1 0 0 1 1 1 1 YwhD family Septin PF00735.13 KEG14763.1 - 0.0061 15.6 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Septin SRPRB PF09439.5 KEG14763.1 - 0.0064 15.7 0.0 0.0094 15.1 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit NACHT PF05729.7 KEG14763.1 - 0.0081 15.8 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_24 PF13479.1 KEG14763.1 - 0.011 15.2 0.1 0.016 14.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 KEG14763.1 - 0.012 14.7 0.1 0.025 13.7 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 KEG14763.1 - 0.012 14.6 0.1 1.4 7.9 0.0 2.3 2 1 0 2 2 2 0 Zeta toxin ABC_tran PF00005.22 KEG14763.1 - 0.034 14.4 0.1 0.039 14.2 0.1 1.5 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 KEG14763.1 - 0.048 13.1 0.1 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 KEG14763.1 - 0.066 12.9 0.1 0.14 11.8 0.0 1.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B IIGP PF05049.8 KEG14763.1 - 0.077 11.7 0.0 0.095 11.4 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.1 KEG14763.1 - 0.09 12.3 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 KEG14763.1 - 0.12 11.7 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain RNA_helicase PF00910.17 KEG14763.1 - 0.12 12.5 0.0 0.4 10.8 0.0 1.9 1 1 0 1 1 1 0 RNA helicase Acetyltransf_1 PF00583.19 KEG14765.1 - 1.2e-17 63.7 0.1 3e-17 62.4 0.1 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEG14765.1 - 1.7e-13 50.5 0.0 2.5e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KEG14765.1 - 3.3e-08 33.6 0.0 3.9e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KEG14765.1 - 6.9e-08 32.4 0.0 8.1e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KEG14765.1 - 5.1e-06 26.5 0.0 6.5e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEG14765.1 - 7.5e-05 22.4 0.0 0.00022 20.9 0.0 1.7 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.1 KEG14765.1 - 0.00062 19.6 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 KEG14765.1 - 0.0071 16.2 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FemAB PF02388.11 KEG14765.1 - 0.0088 14.7 0.0 0.013 14.2 0.0 1.2 1 0 0 1 1 1 1 FemAB family PRC PF05239.11 KEG14765.1 - 0.014 15.2 0.1 0.044 13.6 0.0 1.8 2 0 0 2 2 2 0 PRC-barrel domain Acetyltransf_3 PF13302.1 KEG14765.1 - 0.063 13.4 0.0 0.085 13.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pkinase PF00069.20 KEG14766.1 - 2.4e-58 197.3 0.0 2.8e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG14766.1 - 2.7e-39 134.7 0.0 3.4e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase SH3_3 PF08239.6 KEG14766.1 - 5.3e-08 32.9 0.0 1e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain Kinase-like PF14531.1 KEG14766.1 - 1e-06 27.9 0.0 1.7e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEG14766.1 - 0.032 13.9 0.0 0.67 9.6 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family MRC1 PF09444.5 KEG14767.1 - 0.0027 18.0 0.6 0.0063 16.8 0.0 1.8 1 1 0 2 2 2 1 MRC1-like domain CDC37_N PF03234.9 KEG14767.1 - 0.036 14.3 1.6 0.34 11.2 0.1 2.0 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding HisKA PF00512.20 KEG14767.1 - 0.12 12.4 0.9 0.4 10.6 0.1 2.2 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain MIT PF04212.13 KEG14767.1 - 0.18 11.6 2.6 0.34 10.8 1.5 1.7 1 1 0 1 1 1 0 MIT (microtubule interacting and transport) domain FHA PF00498.21 KEG14770.1 - 0.00018 21.5 0.0 0.00041 20.4 0.0 1.6 1 0 0 1 1 1 1 FHA domain WD40 PF00400.27 KEG14771.1 - 1.1e-09 37.7 4.9 0.00066 19.4 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat PQQ_3 PF13570.1 KEG14771.1 - 1.8 8.9 8.6 2.4 8.5 0.1 4.1 4 2 1 5 5 5 0 PQQ-like domain zf-CCCH PF00642.19 KEG14772.1 - 0.00098 18.7 10.8 0.14 11.9 2.1 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LRV_FeS PF05484.6 KEG14772.1 - 0.25 10.9 3.7 0.52 9.9 0.1 2.3 2 0 0 2 2 2 0 LRV protein FeS4 cluster zf-CCCH_2 PF14608.1 KEG14772.1 - 2.5 8.2 8.8 1.5 8.9 2.8 2.3 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Na_sulph_symp PF00939.14 KEG14774.1 - 7.4e-18 64.6 39.4 1.4e-17 63.7 27.3 1.7 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region SPX PF03105.14 KEG14774.1 - 1.9e-13 50.8 13.1 2.5e-09 37.3 0.9 3.0 1 1 1 2 2 2 2 SPX domain CitMHS PF03600.11 KEG14774.1 - 1.1e-11 43.9 16.4 1.1e-11 43.9 11.4 2.2 1 1 1 2 2 2 1 Citrate transporter Dor1 PF04124.7 KEG14777.1 - 3.6e-19 68.4 1.1 4.7e-19 68.0 0.7 1.2 1 0 0 1 1 1 1 Dor1-like family Sec5 PF15469.1 KEG14777.1 - 0.008 15.9 0.1 0.015 15.0 0.1 1.4 1 0 0 1 1 1 1 Exocyst complex component Sec5 HLH PF00010.21 KEG14777.1 - 0.082 12.6 0.0 3.2 7.5 0.0 2.5 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain Dynein_heavy PF03028.10 KEG14779.1 - 5.7e-192 639.5 0.0 1.4e-191 638.2 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 KEG14779.1 - 2.8e-97 325.8 4.0 2.8e-97 325.8 2.8 2.9 3 0 0 3 3 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 KEG14779.1 - 2.7e-85 285.5 0.0 3.3e-84 282.0 0.0 2.4 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 KEG14779.1 - 1.7e-71 240.3 0.0 3.5e-71 239.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 KEG14779.1 - 1.2e-46 158.3 0.1 5.9e-46 156.1 0.1 2.2 1 1 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_7 PF12775.2 KEG14779.1 - 5.3e-45 153.6 0.1 5.1e-44 150.4 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 MT PF12777.2 KEG14779.1 - 1.2e-39 136.0 7.6 2.6e-39 134.9 5.3 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 KEG14779.1 - 1.9e-23 82.7 0.1 1.4e-06 28.0 0.0 6.5 6 1 0 6 6 6 4 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KEG14779.1 - 3.9e-08 33.5 0.6 0.29 11.2 0.0 6.5 6 0 0 6 6 6 2 AAA domain AAA_16 PF13191.1 KEG14779.1 - 8.3e-08 32.4 10.2 0.055 13.4 0.0 7.2 7 1 0 7 7 7 2 AAA ATPase domain AAA PF00004.24 KEG14779.1 - 2.1e-07 31.2 0.1 0.054 13.6 0.0 4.9 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KEG14779.1 - 6.9e-05 22.7 0.0 0.6 10.0 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KEG14779.1 - 0.00015 21.3 1.0 0.38 10.5 0.0 4.1 4 0 0 4 4 4 1 Part of AAA domain RNA_helicase PF00910.17 KEG14779.1 - 0.00027 21.0 0.0 0.21 11.7 0.0 4.4 4 0 0 4 4 3 1 RNA helicase AAA_18 PF13238.1 KEG14779.1 - 0.0012 19.1 0.1 1.3 9.3 0.0 4.6 4 0 0 4 4 4 1 AAA domain AAA_17 PF13207.1 KEG14779.1 - 0.0066 17.2 3.6 0.37 11.6 0.0 5.4 7 0 0 7 7 5 1 AAA domain Mg_chelatase PF01078.16 KEG14779.1 - 0.079 12.1 0.8 0.64 9.1 0.0 2.8 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI ATP-synt_ab PF00006.20 KEG14779.1 - 0.086 12.3 0.0 22 4.4 0.0 3.4 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Ribosomal_L14e PF01929.12 KEG14780.1 - 2.2e-23 82.3 4.8 2.2e-23 82.3 3.3 2.2 2 0 0 2 2 2 1 Ribosomal protein L14 KOW PF00467.24 KEG14780.1 - 1.8e-06 27.4 0.6 3.1e-06 26.6 0.4 1.4 1 0 0 1 1 1 1 KOW motif Ldh_1_N PF00056.18 KEG14782.1 - 1.3e-32 112.5 0.2 2.2e-32 111.7 0.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KEG14782.1 - 1.4e-32 112.8 0.0 3e-32 111.7 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain RmlD_sub_bind PF04321.12 KEG14782.1 - 0.0069 15.3 0.5 0.097 11.5 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain LRR_8 PF13855.1 KEG14783.1 - 0.058 13.1 0.5 40 4.0 0.0 3.8 4 0 0 4 4 4 0 Leucine rich repeat zf-RING_2 PF13639.1 KEG14784.1 - 0.0016 18.1 3.6 0.0049 16.6 2.5 1.9 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KEG14784.1 - 0.031 13.9 7.0 0.24 11.0 4.9 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SlyX PF04102.7 KEG14784.1 - 0.052 13.9 3.6 0.76 10.1 0.4 2.4 2 0 0 2 2 2 0 SlyX FliJ PF02050.11 KEG14784.1 - 0.094 12.7 0.4 0.094 12.7 0.3 2.0 2 0 0 2 2 2 0 Flagellar FliJ protein zf-rbx1 PF12678.2 KEG14784.1 - 0.11 12.6 1.2 0.42 10.7 0.1 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger zf-Apc11 PF12861.2 KEG14784.1 - 1.2 8.9 3.5 0.86 9.4 0.3 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger IQ PF00612.22 KEG14785.1 - 0.16 11.6 7.1 3.7 7.4 0.5 3.5 2 0 0 2 2 2 0 IQ calmodulin-binding motif HSP70 PF00012.15 KEG14786.1 - 4.3e-196 652.4 0.2 5.2e-196 652.1 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KEG14786.1 - 4e-11 42.1 2.9 4.1e-10 38.7 0.2 2.7 3 0 0 3 3 3 1 MreB/Mbl protein FtsA PF14450.1 KEG14786.1 - 9.2e-05 22.2 0.8 0.0035 17.1 0.0 3.4 3 2 0 3 3 3 1 Cell division protein FtsA BcrAD_BadFG PF01869.15 KEG14786.1 - 0.00046 19.5 0.1 0.031 13.5 0.0 2.7 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family DUF4397 PF14344.1 KEG14786.1 - 0.09 13.0 1.9 0.85 9.9 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4397) EutA PF06277.6 KEG14786.1 - 0.15 10.6 3.0 0.099 11.2 0.1 2.1 3 0 0 3 3 3 0 Ethanolamine utilisation protein EutA Hydantoinase_A PF01968.13 KEG14786.1 - 1.4 7.9 9.3 0.93 8.5 0.3 3.1 3 1 1 4 4 4 0 Hydantoinase/oxoprolinase CPSF73-100_C PF11718.3 KEG14787.1 - 0.097 12.0 0.4 0.11 11.8 0.3 1.3 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term DUF4171 PF13775.1 KEG14787.1 - 1.4 9.0 10.7 0.83 9.8 5.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4171) Pex14_N PF04695.8 KEG14787.1 - 1.8 8.6 9.4 3 7.8 6.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Beta-lactamase PF00144.19 KEG14788.1 - 4.1e-08 32.6 0.1 3.1e-07 29.7 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase DUF2804 PF10974.3 KEG14789.1 - 6.5e-13 48.2 0.0 8.1e-13 47.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2804) WW PF00397.21 KEG14791.1 - 0.0015 18.3 0.8 0.0029 17.4 0.5 1.4 1 0 0 1 1 1 1 WW domain TPR_11 PF13414.1 KEG14794.1 - 7.8e-15 54.2 5.1 5.2e-10 38.8 0.2 4.6 2 1 1 4 4 4 2 TPR repeat TPR_2 PF07719.12 KEG14794.1 - 2.4e-12 45.7 3.3 0.0029 17.3 0.0 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 KEG14794.1 - 6.1e-10 38.8 11.7 0.019 15.5 0.0 7.0 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 KEG14794.1 - 3.1e-09 36.0 0.9 0.53 9.9 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 KEG14794.1 - 5.2e-09 35.6 0.2 2.4e-05 24.1 0.1 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEG14794.1 - 7.4e-05 23.0 5.1 0.0026 18.0 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 KEG14794.1 - 0.00015 21.5 0.9 0.00088 19.0 0.7 2.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_15 PF13429.1 KEG14794.1 - 0.00018 20.6 7.8 0.00026 20.1 0.3 3.4 2 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEG14794.1 - 0.00019 20.9 1.2 9.3 6.3 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 KEG14794.1 - 0.00075 19.3 9.5 0.037 13.9 0.1 4.6 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEG14794.1 - 0.0014 19.2 2.6 0.0045 17.6 0.6 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 KEG14794.1 - 0.007 16.4 2.7 3 8.0 0.0 3.7 2 1 2 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KEG14794.1 - 0.023 14.4 3.9 22 5.1 0.0 5.0 4 1 0 4 4 4 0 Tetratricopeptide repeat SYCE1 PF15233.1 KEG14795.1 - 0.00037 20.4 5.3 0.0056 16.6 0.1 2.3 2 0 0 2 2 2 2 Synaptonemal complex central element protein 1 Psu PF07455.6 KEG14795.1 - 0.022 14.2 2.5 0.052 13.0 1.8 1.6 1 0 0 1 1 1 0 Phage polarity suppression protein (Psu) Rubella_Capsid PF05750.6 KEG14795.1 - 0.025 14.0 1.1 0.038 13.4 0.8 1.2 1 0 0 1 1 1 0 Rubella capsid protein IncA PF04156.9 KEG14795.1 - 0.032 13.8 6.4 0.26 10.8 0.1 2.3 2 0 0 2 2 2 0 IncA protein Mnd1 PF03962.10 KEG14795.1 - 0.16 11.5 10.1 1.2 8.7 3.9 2.2 2 0 0 2 2 2 0 Mnd1 family ATG16 PF08614.6 KEG14795.1 - 0.39 10.5 13.8 1.6 8.5 0.8 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF972 PF06156.8 KEG14795.1 - 0.42 10.9 7.5 0.31 11.4 1.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Microtub_assoc PF07989.6 KEG14795.1 - 2.3 8.1 11.7 6.4 6.6 0.9 3.1 2 1 1 3 3 3 0 Microtubule associated GNAT_acetyltr_2 PF13718.1 KEG14796.1 - 2.6e-71 239.0 0.0 4.9e-71 238.1 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 KEG14796.1 - 3.3e-60 202.7 0.0 9.5e-60 201.2 0.0 1.8 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 KEG14796.1 - 8.1e-36 121.6 0.1 2.4e-35 120.1 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 KEG14796.1 - 9.1e-21 73.8 0.1 2.1e-20 72.7 0.1 1.7 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 KEG14796.1 - 0.001 19.1 0.0 0.0048 17.0 0.0 2.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AAA_22 PF13401.1 KEG14796.1 - 0.0059 16.7 0.0 0.97 9.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain Oscp1 PF10188.4 KEG14797.1 - 2.6e-59 199.9 0.1 4.5e-59 199.1 0.1 1.4 1 0 0 1 1 1 1 Organic solute transport protein 1 eIF2A PF08662.6 KEG14800.1 - 1.9e-15 57.1 0.0 7.1e-15 55.2 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A FAM60A PF15396.1 KEG14801.1 - 0.027 14.2 1.8 0.045 13.5 1.2 1.3 1 0 0 1 1 1 0 Protein Family FAM60A SR-25 PF10500.4 KEG14801.1 - 0.63 9.4 13.4 1.1 8.6 9.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.4 KEG14801.1 - 0.63 8.2 7.9 0.89 7.7 5.4 1.1 1 0 0 1 1 1 0 Transmembrane protein FGF-BP1 PF06473.7 KEG14801.1 - 0.69 9.4 4.3 1 8.9 3.0 1.2 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Hid1 PF12722.2 KEG14801.1 - 1 6.9 4.5 1.4 6.5 3.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Carn_acyltransf PF00755.15 KEG14802.1 - 2.1e-151 504.9 0.0 3e-151 504.4 0.0 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Imm16 PF15565.1 KEG14802.1 - 0.054 13.3 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Immunity protein 16 Macro PF01661.16 KEG14803.1 - 3.6e-34 117.1 0.1 5.4e-34 116.6 0.1 1.3 1 0 0 1 1 1 1 Macro domain Methyltransf_32 PF13679.1 KEG14805.1 - 8.4e-15 54.6 0.8 2.9e-07 30.2 0.0 3.1 3 0 0 3 3 3 2 Methyltransferase domain HALZ PF02183.13 KEG14806.1 - 0.053 13.2 2.5 6.6 6.5 0.1 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper LAMTOR PF15454.1 KEG14806.1 - 0.38 11.0 2.5 0.56 10.5 0.8 2.0 2 0 0 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Macoilin PF09726.4 KEG14806.1 - 0.52 8.5 6.8 0.069 11.4 0.2 2.0 2 0 0 2 2 2 0 Transmembrane protein Troponin PF00992.15 KEG14806.1 - 0.61 10.1 11.3 0.049 13.7 1.3 2.2 2 0 0 2 2 2 0 Troponin DUF4404 PF14357.1 KEG14806.1 - 4.6 7.7 6.6 0.8 10.1 1.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) ubiquitin PF00240.18 KEG14808.1 - 0.0078 15.5 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family CTP_transf_2 PF01467.21 KEG14810.1 - 7.7e-14 52.0 0.0 1.8e-13 50.7 0.0 1.7 1 1 0 1 1 1 1 Cytidylyltransferase Cyt-b5 PF00173.23 KEG14811.1 - 1.9e-18 66.0 0.0 2.6e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ALO PF04030.9 KEG14812.1 - 2.4e-77 260.0 6.8 1.1e-74 251.3 1.6 2.2 2 0 0 2 2 2 2 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 KEG14812.1 - 3.4e-25 88.1 0.1 5.7e-25 87.3 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain SDA1 PF05285.7 KEG14813.1 - 2e-38 132.5 4.8 2e-38 132.5 0.3 2.1 2 0 0 2 2 2 1 SDA1 NUC130_3NT PF08158.7 KEG14813.1 - 2.5e-17 62.8 0.0 7.5e-17 61.3 0.0 1.9 1 0 0 1 1 1 1 NUC130/3NT domain Syja_N PF02383.13 KEG14814.1 - 2.6e-27 95.4 0.0 1e-26 93.5 0.0 1.8 2 0 0 2 2 2 1 SacI homology domain GST_C_3 PF14497.1 KEG14815.1 - 2.4e-06 27.9 0.0 3.6e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KEG14815.1 - 0.083 12.8 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 KEG14816.1 - 0.00015 21.6 0.0 0.00074 19.4 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin Prok-RING_4 PF14447.1 KEG14816.1 - 0.0098 15.4 0.2 0.02 14.4 0.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 YtzH PF14165.1 KEG14817.1 - 0.038 14.2 1.4 0.14 12.4 1.0 2.0 1 0 0 1 1 1 0 YtzH-like protein DUF1168 PF06658.7 KEG14818.1 - 6.1 6.3 13.3 4.7 6.7 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) MPC PF03650.8 KEG14819.1 - 1e-11 44.8 0.3 1.2e-11 44.5 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Vac14_Fig4_bd PF11916.3 KEG14820.1 - 3e-54 182.9 2.4 8.1e-54 181.5 1.7 1.8 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 KEG14820.1 - 1.7e-05 25.1 0.1 0.00014 22.1 0.0 2.4 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region Kinesin PF00225.18 KEG14822.1 - 4.1e-67 226.2 0.0 8.8e-67 225.1 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Tropomyosin_1 PF12718.2 KEG14822.1 - 0.00082 19.2 43.7 0.0069 16.2 1.2 5.5 3 2 2 5 5 5 2 Tropomyosin like DUF842 PF05811.8 KEG14822.1 - 0.01 15.2 2.6 0.01 15.2 1.8 3.2 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF842) AAA_22 PF13401.1 KEG14822.1 - 0.014 15.4 0.1 0.13 12.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain LXG PF04740.7 KEG14822.1 - 0.018 14.8 3.6 0.019 14.7 0.7 2.5 1 1 0 1 1 1 0 LXG domain of WXG superfamily MMR_HSR1 PF01926.18 KEG14822.1 - 0.02 14.8 0.2 2.6 8.0 0.0 3.2 3 0 0 3 3 3 0 50S ribosome-binding GTPase DUF2746 PF10874.3 KEG14822.1 - 0.064 13.4 9.2 9.1 6.5 0.3 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2746) TBPIP PF07106.8 KEG14822.1 - 1.7 8.1 25.0 0.11 12.0 3.1 4.9 1 1 3 5 5 5 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1409 PF07197.7 KEG14822.1 - 2.9 8.0 17.4 19 5.3 0.1 5.4 5 0 0 5 5 5 0 Protein of unknown function (DUF1409) DUF3683 PF12447.3 KEG14822.1 - 3.6 7.4 7.7 42 3.9 0.3 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3683) TMF_TATA_bd PF12325.3 KEG14822.1 - 5.7 6.6 33.9 1.2 8.8 1.4 5.3 4 2 1 5 5 5 0 TATA element modulatory factor 1 TATA binding GAS PF13851.1 KEG14822.1 - 7.9 5.6 27.7 0.22 10.7 0.6 4.5 1 1 2 5 5 5 0 Growth-arrest specific micro-tubule binding Kelch_6 PF13964.1 KEG14823.1 - 6.1e-11 42.0 10.4 0.027 14.6 0.2 6.9 4 2 2 6 6 6 3 Kelch motif Kelch_4 PF13418.1 KEG14823.1 - 8e-08 31.9 8.4 0.38 10.5 0.1 6.4 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_2 PF07646.10 KEG14823.1 - 2e-07 30.5 1.9 2.7 7.9 0.0 5.5 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 KEG14823.1 - 3e-07 30.2 0.7 0.93 9.5 0.1 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.1 KEG14823.1 - 0.00014 21.9 8.9 0.0026 17.8 0.0 5.0 5 1 0 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.20 KEG14823.1 - 0.00026 20.4 0.1 2.2 7.8 0.0 4.8 6 0 0 6 6 6 2 Kelch motif DUF2693 PF10902.3 KEG14823.1 - 0.043 13.7 0.0 0.086 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2693) Rubredoxin PF00301.15 KEG14825.1 - 0.0076 16.1 0.1 0.024 14.5 0.1 1.8 1 0 0 1 1 1 1 Rubredoxin WD40 PF00400.27 KEG14826.1 - 3.5e-10 39.3 17.8 0.005 16.6 0.0 7.9 9 0 0 9 9 9 3 WD domain, G-beta repeat DUF3832 PF12909.2 KEG14826.1 - 0.012 15.6 0.1 0.033 14.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3832) Pkinase PF00069.20 KEG14828.1 - 2.5e-66 223.5 0.0 3.2e-66 223.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG14828.1 - 2.2e-45 154.7 0.0 3.6e-45 154.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG14828.1 - 3.1e-08 32.9 0.0 2.6e-07 29.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Med3 PF11593.3 KEG14828.1 - 4.8 6.3 13.0 8.2 5.5 9.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal EMP24_GP25L PF01105.19 KEG14830.1 - 4.5e-23 81.9 0.1 6.8e-23 81.3 0.1 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Fumarate_red_D PF02313.12 KEG14830.1 - 0.053 13.4 1.2 0.076 12.9 0.2 1.7 2 0 0 2 2 2 0 Fumarate reductase subunit D tRNA-synt_1b PF00579.20 KEG14832.1 - 2.9e-60 203.8 0.0 8.7e-53 179.3 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class I (W and Y) PX PF00787.19 KEG14833.1 - 1.5e-07 31.1 0.4 2.7e-07 30.3 0.3 1.3 1 0 0 1 1 1 1 PX domain DnaJ PF00226.26 KEG14834.1 - 8e-21 73.5 3.4 8e-21 73.5 2.4 1.9 2 0 0 2 2 2 1 DnaJ domain TPR_11 PF13414.1 KEG14834.1 - 6.5e-16 57.7 13.5 5.9e-09 35.4 0.2 5.7 5 0 0 5 5 5 2 TPR repeat TPR_19 PF14559.1 KEG14834.1 - 2.5e-11 43.7 24.5 0.0055 17.0 0.1 5.7 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 KEG14834.1 - 1.2e-09 38.5 25.9 0.0066 17.0 0.1 6.0 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 KEG14834.1 - 7.2e-08 32.3 27.2 0.0054 17.2 1.5 6.8 4 3 2 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEG14834.1 - 1.2e-06 28.0 25.6 0.019 14.8 0.4 7.2 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.1 KEG14834.1 - 0.00017 21.3 22.5 0.043 13.6 0.2 5.4 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 KEG14834.1 - 0.00035 20.0 12.8 0.29 10.8 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 KEG14834.1 - 0.022 14.5 3.1 1.5 8.8 0.0 4.3 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 KEG14834.1 - 0.041 14.0 6.1 0.91 9.8 0.0 5.0 7 0 0 7 7 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 KEG14834.1 - 0.058 13.2 2.2 5.8 6.9 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat WHIM3 PF15614.1 KEG14834.1 - 0.14 11.9 0.1 0.42 10.4 0.1 1.8 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 3 TPR_20 PF14561.1 KEG14834.1 - 0.21 11.6 12.0 1.1 9.3 0.7 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 KEG14834.1 - 0.41 10.8 4.1 0.53 10.5 0.1 2.8 2 1 1 3 3 3 0 Alkyl sulfatase dimerisation TPR_12 PF13424.1 KEG14834.1 - 1.2 9.0 16.3 3.4 7.6 0.3 4.5 3 2 1 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KEG14834.1 - 2.7 7.9 9.4 0.53 10.2 0.1 4.1 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 KEG14834.1 - 4.8 7.8 15.3 10 6.8 0.1 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat SHMT PF00464.14 KEG14835.1 - 1e-170 567.4 0.0 1.3e-170 567.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 KEG14835.1 - 0.0037 16.4 0.0 0.0084 15.2 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase EMP24_GP25L PF01105.19 KEG14837.1 - 1.1e-43 149.0 0.1 2e-43 148.2 0.0 1.4 2 0 0 2 2 2 1 emp24/gp25L/p24 family/GOLD NIPSNAP PF07978.8 KEG14838.1 - 0.13 12.2 0.4 4.6 7.2 0.0 2.6 3 0 0 3 3 3 0 NIPSNAP DUF3456 PF11938.3 KEG14839.1 - 5.4e-12 45.9 0.2 9.1e-12 45.2 0.2 1.3 1 0 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP Potyvirid-P3 PF13608.1 KEG14839.1 - 0.017 14.2 0.3 0.024 13.7 0.2 1.1 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein Endosulfine PF04667.12 KEG14840.1 - 3e-05 23.8 0.9 3.4e-05 23.7 0.6 1.3 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region DUF4200 PF13863.1 KEG14841.1 - 2.7e-32 111.3 14.1 2.7e-32 111.3 9.8 4.5 4 1 0 4 4 4 2 Domain of unknown function (DUF4200) PAPS_reduct PF01507.14 KEG14841.1 - 7.9 6.2 12.8 0.21 11.4 1.7 3.0 2 1 1 3 3 3 0 Phosphoadenosine phosphosulfate reductase family Mucin PF01456.12 KEG14842.1 - 0.0089 15.8 8.6 0.0096 15.7 6.0 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF3439 PF11921.3 KEG14842.1 - 0.55 9.9 9.5 0.84 9.3 6.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF2040 PF09745.4 KEG14842.1 - 0.73 9.6 6.6 1.3 8.9 4.6 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 55 (DUF2040) Pol_alpha_B_N PF08418.5 KEG14842.1 - 2.1 7.8 6.9 2.7 7.4 4.8 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Dicty_REP PF05086.7 KEG14842.1 - 2.5 5.7 6.2 3 5.4 4.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.6 KEG14842.1 - 3.9 5.3 12.0 4.7 5.0 8.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF367 PF04034.8 KEG14843.1 - 5.3e-45 152.1 0.0 7.3e-45 151.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 KEG14843.1 - 7.4e-08 31.8 0.1 1.5e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI DUF2722 PF10846.3 KEG14843.1 - 0.32 9.9 5.9 0.39 9.6 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CDC45 PF02724.9 KEG14843.1 - 0.69 7.8 13.4 0.85 7.5 9.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 KEG14843.1 - 0.83 8.0 19.5 0.9 7.9 13.5 1.0 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 KEG14843.1 - 1.6 7.9 20.2 1.8 7.7 14.0 1.1 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.7 KEG14843.1 - 6.3 5.9 12.1 8.7 5.5 8.4 1.2 1 0 0 1 1 1 0 NOA36 protein TFIIA PF03153.8 KEG14843.1 - 6.6 6.5 15.1 8 6.2 10.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 KEG14843.1 - 7.2 4.3 24.5 8.2 4.1 17.0 1.0 1 0 0 1 1 1 0 Nop14-like family Paf1 PF03985.8 KEG14843.1 - 9.2 4.8 17.3 11 4.6 12.0 1.1 1 0 0 1 1 1 0 Paf1 Acyltransferase PF01553.16 KEG14846.1 - 1.7e-19 69.5 0.0 3.4e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase DNAPolymera_Pol PF11590.3 KEG14846.1 - 0.072 12.7 0.1 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase catalytic subunit Pol DUF3007 PF11460.3 KEG14846.1 - 0.65 10.0 2.4 1.2 9.2 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) DUF4094 PF13334.1 KEG14847.1 - 0.0046 17.3 1.2 0.0046 17.3 0.8 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4094) FdsD PF11390.3 KEG14847.1 - 0.14 12.3 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 NADH-dependant formate dehydrogenase delta subunit FdsD CTDII PF01556.13 KEG14848.1 - 5.8e-22 77.3 0.1 8.3e-17 60.8 0.0 2.6 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 KEG14848.1 - 1.4e-15 56.7 0.1 2.3e-15 56.0 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain DUF2763 PF10961.3 KEG14849.1 - 4 7.8 19.1 28 5.1 0.8 5.4 1 1 6 7 7 7 0 Protein of unknown function (DUF2763) SlyX PF04102.7 KEG14850.1 - 0.002 18.4 5.4 0.086 13.2 3.8 3.8 1 1 0 1 1 1 1 SlyX DUF599 PF04654.7 KEG14850.1 - 0.3 10.1 0.5 0.55 9.3 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF599 HALZ PF02183.13 KEG14851.1 - 0.93 9.2 6.5 14 5.4 0.0 4.1 4 0 0 4 4 4 0 Homeobox associated leucine zipper DUF647 PF04884.9 KEG14852.1 - 4.9e-29 101.2 5.0 8.2e-29 100.5 3.4 1.3 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis DUF2838 PF10998.3 KEG14852.1 - 4.5 7.2 9.5 15 5.4 2.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2838) DUF4557 PF15101.1 KEG14854.1 - 0.043 13.6 1.1 0.069 12.9 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Tmemb_14 PF03647.8 KEG14855.1 - 1.5e-18 66.9 9.1 1.9e-18 66.6 6.3 1.2 1 0 0 1 1 1 1 Transmembrane proteins 14C Oxidored_q1_N PF00662.15 KEG14855.1 - 0.0011 18.4 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus FUSC_2 PF13515.1 KEG14855.1 - 0.0017 18.2 3.0 0.0022 17.9 2.1 1.2 1 0 0 1 1 1 1 Fusaric acid resistance protein-like DUF2232 PF09991.4 KEG14855.1 - 0.25 10.3 6.4 0.44 9.5 4.4 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2232) YjgP_YjgQ PF03739.9 KEG14855.1 - 0.29 9.8 2.1 0.23 10.1 0.2 1.6 1 1 1 2 2 2 0 Predicted permease YjgP/YjgQ family VIT1 PF01988.14 KEG14855.1 - 3.7 6.9 9.5 1.2 8.5 1.7 2.1 2 0 0 2 2 2 0 VIT family CBFD_NFYB_HMF PF00808.18 KEG14857.1 - 0.00092 19.2 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Cation_efflux PF01545.16 KEG14858.1 - 2.3e-13 49.8 13.9 6.9e-13 48.2 9.6 1.9 1 1 0 1 1 1 1 Cation efflux family Cpn60_TCP1 PF00118.19 KEG14861.1 - 7.9e-118 394.1 4.4 9.3e-118 393.9 3.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ras PF00071.17 KEG14862.1 - 2.1e-37 127.9 0.0 2.6e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEG14862.1 - 2.7e-18 66.5 0.0 4.1e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEG14862.1 - 4.4e-10 39.0 0.0 5.4e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KEG14862.1 - 9.2e-08 31.5 0.0 1.2e-07 31.0 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KEG14862.1 - 6.8e-06 25.6 0.0 0.00027 20.4 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KEG14862.1 - 2.2e-05 23.7 0.0 4.1e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KEG14862.1 - 4.6e-05 23.3 0.0 8.6e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KEG14862.1 - 0.0006 19.4 0.1 0.0011 18.6 0.0 1.4 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 KEG14862.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Sod_Fe_C PF02777.13 KEG14863.1 - 1.9e-44 149.8 1.0 8.4e-44 147.7 0.6 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KEG14863.1 - 2.8e-22 78.7 0.8 8.4e-22 77.2 0.0 2.0 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Pkinase PF00069.20 KEG14864.1 - 4.4e-54 183.3 0.0 1.7e-53 181.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG14864.1 - 3.5e-30 104.9 0.0 1.4e-29 102.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 KEG14864.1 - 2.5e-06 27.6 0.0 5.3e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 KEG14864.1 - 0.00038 19.5 0.0 0.00053 19.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PH_9 PF15410.1 KEG14864.1 - 0.0011 19.1 0.0 0.0024 17.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 KEG14864.1 - 0.0017 18.6 0.0 0.0039 17.4 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain GSH_synthase PF03199.10 KEG14865.1 - 0.00092 19.2 0.1 0.0024 17.9 0.0 1.6 2 0 0 2 2 2 1 Eukaryotic glutathione synthase SMN PF06003.7 KEG14865.1 - 0.006 15.7 3.5 0.055 12.5 0.1 2.2 1 1 0 2 2 2 2 Survival motor neuron protein (SMN) GRAM PF02893.15 KEG14866.1 - 2.2e-10 39.9 0.0 6.2e-10 38.4 0.0 1.8 1 0 0 1 1 1 1 GRAM domain SPA PF08616.5 KEG14867.1 - 5.9e-28 96.8 0.0 1.2e-27 95.8 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.7 KEG14867.1 - 1.1e-06 28.6 0.0 0.00014 21.9 0.0 2.4 2 0 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF2347 PF09804.4 KEG14867.1 - 0.00049 19.4 0.0 0.0014 18.0 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.4 KEG14867.1 - 0.00066 18.2 0.0 0.014 13.8 0.0 2.2 1 1 1 2 2 2 1 Transport protein Avl9 TPR_11 PF13414.1 KEG14869.1 - 1.6e-25 88.5 3.4 3.5e-18 64.9 0.6 2.6 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KEG14869.1 - 1.1e-23 81.7 2.7 8.6e-07 28.3 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEG14869.1 - 1.7e-16 58.7 8.1 3.2e-05 23.4 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 KEG14869.1 - 2.9e-09 36.3 0.7 0.02 15.0 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEG14869.1 - 5.7e-09 35.7 1.9 1.2e-05 25.1 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEG14869.1 - 2.5e-08 34.3 0.1 1.9e-06 28.3 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEG14869.1 - 1e-07 31.1 1.7 0.18 11.6 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEG14869.1 - 4.8e-07 29.8 0.1 0.26 12.0 0.0 4.1 2 1 2 4 4 3 2 Tetratricopeptide repeat SGT1 PF07093.6 KEG14869.1 - 7.7e-07 27.8 0.7 7.7e-07 27.8 0.5 1.7 2 0 0 2 2 2 1 SGT1 protein TPR_7 PF13176.1 KEG14869.1 - 1.7e-06 27.3 1.8 0.52 10.2 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEG14869.1 - 3.3e-05 24.1 0.2 0.029 14.7 0.1 3.1 1 1 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 KEG14869.1 - 7.6e-05 22.7 5.7 0.0016 18.5 1.4 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KEG14869.1 - 9.3e-05 22.2 1.2 0.0081 15.9 0.1 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KEG14869.1 - 0.00097 18.9 3.7 0.67 9.8 0.0 3.5 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat Ins_allergen_rp PF06757.8 KEG14869.1 - 0.0012 18.3 0.4 0.019 14.4 0.3 2.4 1 1 0 1 1 1 1 Insect allergen related repeat, nitrile-specifier detoxification TPR_3 PF07720.7 KEG14869.1 - 0.0058 16.3 0.5 0.045 13.5 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.13 KEG14869.1 - 0.0061 16.4 1.5 0.79 9.6 0.1 3.2 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TOM20_plant PF06552.7 KEG14869.1 - 0.064 12.8 0.9 1 8.9 0.0 2.8 1 1 1 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 Integrin_b_cyt PF08725.6 KEG14869.1 - 0.12 11.7 1.7 2.1 7.7 0.0 2.8 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain TPR_6 PF13174.1 KEG14869.1 - 0.31 11.6 1.4 38 5.0 0.0 3.6 3 0 0 3 3 2 0 Tetratricopeptide repeat Sod_Fe_C PF02777.13 KEG14872.1 - 7e-10 38.7 0.0 1.3e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KEG14872.1 - 0.00011 22.3 0.0 0.00024 21.3 0.0 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain zf-CCCH PF00642.19 KEG14874.1 - 1.7e-06 27.5 4.4 2.9e-06 26.8 3.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KEG14874.1 - 0.021 14.8 0.3 0.06 13.3 0.2 1.8 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type DUF872 PF05915.7 KEG14875.1 - 1.1e-12 47.7 0.0 1.2e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) Claudin_2 PF13903.1 KEG14875.1 - 4.5e-05 23.1 0.1 5.5e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF3592 PF12158.3 KEG14875.1 - 0.16 11.7 1.5 0.28 10.9 1.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3592) DUF3040 PF11239.3 KEG14875.1 - 7.7 6.6 5.9 38 4.4 4.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) BacA PF02673.13 KEG14876.1 - 0.09 11.9 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacitracin resistance protein BacA BMC PF00936.14 KEG14876.1 - 0.12 12.0 0.6 6.7 6.4 0.0 2.2 1 1 1 2 2 2 0 BMC domain SOCS PF12610.3 KEG14876.1 - 0.23 11.7 3.7 0.83 10.0 1.0 2.5 2 1 0 2 2 2 0 Suppressor of cytokine signalling Cpn60_TCP1 PF00118.19 KEG14878.1 - 9.9e-104 347.6 1.0 1.1e-103 347.4 0.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RabGAP-TBC PF00566.13 KEG14880.1 - 3.3e-37 128.0 0.0 6.7e-37 127.0 0.0 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain R3H PF01424.17 KEG14880.1 - 0.0018 17.9 0.0 0.047 13.3 0.0 2.8 3 0 0 3 3 3 1 R3H domain DUF4329 PF14220.1 KEG14881.1 - 0.023 14.6 0.0 0.027 14.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4329) Myosin_head PF00063.16 KEG14883.1 - 1.4e-13 49.8 0.1 1.4e-13 49.8 0.1 3.5 2 2 0 3 3 3 2 Myosin head (motor domain) FUN14 PF04930.10 KEG14884.1 - 0.036 14.3 0.1 0.054 13.7 0.1 1.3 1 0 0 1 1 1 0 FUN14 family DIX PF00778.12 KEG14885.1 - 0.047 13.4 0.0 0.09 12.5 0.0 1.4 1 0 0 1 1 1 0 DIX domain Bunya_NS-S PF01104.12 KEG14887.1 - 0.0048 16.3 0.1 0.0071 15.7 0.0 1.2 1 0 0 1 1 1 1 Bunyavirus non-structural protein NS-s Not3 PF04065.10 KEG14887.1 - 0.04 13.1 3.5 0.053 12.7 2.4 1.2 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component ApoO PF09769.4 KEG14887.1 - 0.07 12.8 0.2 0.079 12.6 0.1 1.2 1 0 0 1 1 1 0 Apolipoprotein O GAT PF03127.9 KEG14887.1 - 0.087 12.8 2.7 0.12 12.4 1.8 1.2 1 0 0 1 1 1 0 GAT domain DUF342 PF03961.8 KEG14887.1 - 0.11 10.8 3.1 0.12 10.7 2.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) GP41 PF00517.12 KEG14887.1 - 0.56 9.7 4.3 0.46 10.0 0.8 1.9 1 1 1 2 2 2 0 Retroviral envelope protein IncA PF04156.9 KEG14887.1 - 0.92 9.0 5.7 1.2 8.7 3.9 1.1 1 0 0 1 1 1 0 IncA protein FUN14 PF04930.10 KEG14889.1 - 5.2e-21 74.7 2.1 6.6e-21 74.4 1.4 1.1 1 0 0 1 1 1 1 FUN14 family EF-hand_1 PF00036.27 KEG14889.1 - 0.011 14.9 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.1 KEG14889.1 - 0.078 12.3 0.3 0.13 11.6 0.2 1.3 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 KEG14889.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain PPR_3 PF13812.1 KEG14890.1 - 5.5e-08 32.4 17.7 0.049 13.9 0.0 8.3 9 0 0 9 9 9 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 KEG14890.1 - 9.5e-08 31.9 0.0 0.19 11.6 0.0 5.3 4 1 1 5 5 5 2 PPR repeat family TPR_14 PF13428.1 KEG14890.1 - 9.3e-07 28.9 9.7 4.7 8.1 0.3 7.1 4 2 3 7 7 7 2 Tetratricopeptide repeat PPR PF01535.15 KEG14890.1 - 2.5e-05 23.9 8.5 0.27 11.3 0.0 6.6 7 0 0 7 7 7 2 PPR repeat TPR_16 PF13432.1 KEG14890.1 - 5.6e-05 23.6 6.6 2.8 8.7 0.1 5.0 4 2 0 4 4 4 3 Tetratricopeptide repeat P3A PF08727.6 KEG14890.1 - 0.0051 16.1 0.3 0.014 14.7 0.0 1.8 2 0 0 2 2 2 1 Poliovirus 3A protein like Aldedh PF00171.17 KEG14892.1 - 4.7e-122 407.6 0.0 6.5e-122 407.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KEG14892.1 - 4.6e-06 26.0 0.0 1.3e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Pkinase PF00069.20 KEG14893.1 - 2e-47 161.5 0.0 2.5e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG14893.1 - 1.6e-13 50.3 0.0 2.1e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEG14893.1 - 3.1e-05 23.8 0.8 4.2e-05 23.3 0.5 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KEG14893.1 - 0.0001 21.4 0.1 0.00038 19.5 0.0 1.9 1 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4515 PF14988.1 KEG14894.1 - 0.0015 18.2 18.7 0.12 12.0 5.3 2.7 2 1 0 2 2 2 2 Domain of unknown function (DUF4515) Taxilin PF09728.4 KEG14894.1 - 0.56 9.2 19.8 0.024 13.7 7.3 2.1 1 1 1 2 2 2 0 Myosin-like coiled-coil protein Kinetocho_Slk19 PF12709.2 KEG14894.1 - 0.81 9.7 12.1 2.4 8.3 0.7 2.7 2 1 0 2 2 2 0 Central kinetochore-associated DUF4085 PF13315.1 KEG14894.1 - 2.1 7.6 8.7 1.4 8.2 3.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4085) V_ATPase_I PF01496.14 KEG14894.1 - 9.6 3.9 8.3 16 3.2 5.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PI-PLC-X PF00388.14 KEG14898.1 - 3e-58 195.3 0.0 5.9e-58 194.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KEG14898.1 - 5.2e-34 116.7 0.0 9.2e-34 115.9 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_6 PF13405.1 KEG14898.1 - 1.9e-10 39.7 0.4 0.00019 21.0 0.0 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 KEG14898.1 - 3.8e-10 38.3 0.3 0.00023 20.2 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 KEG14898.1 - 1.1e-09 38.2 1.0 1e-08 35.1 0.2 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 KEG14898.1 - 9.1e-08 31.1 1.2 5.8e-05 22.2 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_10 PF14788.1 KEG14898.1 - 1.5e-07 30.9 0.6 3.5e-07 29.7 0.0 1.9 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KEG14898.1 - 2.9e-06 26.7 0.1 0.022 14.3 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KEG14898.1 - 0.00045 20.2 0.0 0.001 19.0 0.0 1.6 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region C2 PF00168.25 KEG14898.1 - 0.0012 18.6 0.2 0.0032 17.2 0.1 1.8 1 0 0 1 1 1 1 C2 domain EF-hand_4 PF12763.2 KEG14898.1 - 0.017 14.8 0.1 0.14 11.9 0.1 2.2 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand zf-CHCC PF10276.4 KEG14899.1 - 0.0006 19.6 2.2 0.0006 19.6 1.5 2.0 2 0 0 2 2 2 1 Zinc-finger domain Gp_dh_N PF00044.19 KEG14900.1 - 4.2e-56 189.0 0.2 6.3e-56 188.5 0.2 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Gp_dh_C PF02800.15 KEG14900.1 - 7.2e-30 103.5 0.4 1.6e-29 102.3 0.0 1.7 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain TrkA_N PF02254.13 KEG14900.1 - 0.097 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain RRM_1 PF00076.17 KEG14901.1 - 1.4e-19 69.4 0.1 6.7e-09 35.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG14901.1 - 1.2e-09 38.0 0.1 0.00037 20.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG14901.1 - 2.2e-08 33.7 0.1 9.2e-06 25.4 0.0 3.0 2 2 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Abhydrolase_6 PF12697.2 KEG14902.1 - 0.01 15.6 0.9 0.021 14.7 0.1 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family RNA_pol_Rpb4 PF03874.11 KEG14903.1 - 5.7e-05 23.0 0.0 0.00011 22.1 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb4 DUF465 PF04325.8 KEG14903.1 - 0.097 12.3 0.5 0.19 11.4 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF465) TFIIA PF03153.8 KEG14905.1 - 0.78 9.5 22.7 0.64 9.8 12.0 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PPR_3 PF13812.1 KEG14906.1 - 9.5e-05 22.3 1.2 0.3 11.4 0.0 4.9 4 1 1 5 5 5 1 Pentatricopeptide repeat domain PPR PF01535.15 KEG14906.1 - 0.00041 20.1 0.0 1.1 9.3 0.0 3.4 3 0 0 3 3 3 2 PPR repeat PPR_2 PF13041.1 KEG14906.1 - 0.0035 17.2 0.3 2.2 8.3 0.1 3.5 3 1 1 4 4 4 2 PPR repeat family Metallophos PF00149.23 KEG14907.1 - 0.0001 21.7 0.2 0.00023 20.6 0.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KEG14907.1 - 0.0015 18.3 0.4 0.0023 17.7 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain IncA PF04156.9 KEG14908.1 - 0.15 11.6 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 IncA protein Rad51 PF08423.6 KEG14909.1 - 1.9e-07 30.2 3.8 0.0082 15.0 1.7 2.5 2 1 0 2 2 2 2 Rad51 AAA_25 PF13481.1 KEG14909.1 - 1.3e-05 24.6 4.5 4.6e-05 22.9 3.1 1.9 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 KEG14909.1 - 0.00083 18.5 0.0 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_19 PF13245.1 KEG14909.1 - 0.0022 17.7 0.4 0.0022 17.7 0.3 2.7 3 1 0 3 3 3 1 Part of AAA domain RecA PF00154.16 KEG14909.1 - 0.016 14.2 0.4 0.033 13.2 0.0 1.6 2 0 0 2 2 2 0 recA bacterial DNA recombination protein Mgm101p PF06420.7 KEG14909.1 - 0.14 11.4 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial genome maintenance MGM101 V_ATPase_I PF01496.14 KEG14910.1 - 2.1 6.0 14.9 0.67 7.7 0.1 3.1 3 0 0 3 3 3 0 V-type ATPase 116kDa subunit family Reo_sigmaC PF04582.7 KEG14910.1 - 2.7 7.0 8.2 7.6 5.6 1.4 3.0 3 0 0 3 3 3 0 Reovirus sigma C capsid protein CMD PF02627.15 KEG14911.1 - 0.075 12.8 3.1 0.079 12.8 0.2 2.2 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family M60-like PF13402.1 KEG14912.1 - 0.0053 15.7 0.2 1.6 7.5 0.0 2.2 2 0 0 2 2 2 2 Peptidase M60-like family TPR_11 PF13414.1 KEG14914.1 - 0.00018 21.0 6.2 0.093 12.3 0.0 3.9 3 1 0 3 3 3 2 TPR repeat TPR_17 PF13431.1 KEG14914.1 - 0.0031 17.5 3.4 2 8.8 0.0 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat F-box-like PF12937.2 KEG14914.1 - 0.021 14.5 0.1 0.071 12.8 0.1 1.9 1 0 0 1 1 1 0 F-box-like TPR_9 PF13371.1 KEG14914.1 - 0.077 12.8 12.5 2.5 8.0 0.2 4.9 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEG14914.1 - 1 10.1 6.5 20 6.1 0.0 4.7 4 1 0 4 4 4 0 Tetratricopeptide repeat Cofilin_ADF PF00241.15 KEG14915.1 - 1.3e-28 99.4 0.0 1.4e-28 99.2 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Mito_fiss_reg PF05308.6 KEG14916.1 - 0.08 12.3 6.6 2.2 7.5 2.7 2.5 2 0 0 2 2 2 0 Mitochondrial fission regulator MCM_N PF14551.1 KEG14916.1 - 0.17 12.3 0.0 0.29 11.6 0.0 1.3 1 0 0 1 1 1 0 MCM N-terminal domain DDE_3 PF13358.1 KEG14916.1 - 0.18 11.5 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF2360 PF10152.4 KEG14916.1 - 3.2 8.0 9.5 4.1 7.6 3.0 2.8 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) CAP_N PF01213.14 KEG14916.1 - 5.5 6.1 11.3 14 4.8 0.1 2.4 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal MerR PF00376.18 KEG14917.1 - 0.064 12.8 0.1 0.25 10.9 0.0 2.1 2 0 0 2 2 2 0 MerR family regulatory protein RNase_T PF00929.19 KEG14918.1 - 1.2e-23 84.1 0.0 8.2e-23 81.4 0.0 2.1 1 1 0 1 1 1 1 Exonuclease LcrG PF07216.7 KEG14918.1 - 0.81 9.7 5.2 3.3 7.8 0.2 2.9 3 1 0 3 3 3 0 LcrG protein RNase_T PF00929.19 KEG14919.1 - 1.5e-22 80.6 0.0 2.6e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 Exonuclease RNase_T PF00929.19 KEG14920.1 - 5.8e-22 78.7 0.0 1e-21 77.9 0.0 1.4 1 0 0 1 1 1 1 Exonuclease Ank_2 PF12796.2 KEG14921.1 - 4.9e-12 46.0 0.1 1.1e-11 44.9 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEG14921.1 - 1e-10 41.8 0.4 6.6e-05 23.3 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KEG14921.1 - 5.7e-10 38.5 2.2 0.064 13.0 0.0 4.1 3 1 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 KEG14921.1 - 1.2e-07 31.2 1.3 0.015 15.4 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 KEG14921.1 - 0.00094 19.3 2.5 0.062 13.5 0.3 3.5 2 1 1 3 3 3 1 Ankyrin repeats (many copies) FUSC PF04632.7 KEG14922.1 - 9.3 4.5 9.7 0.87 7.9 1.8 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family ResIII PF04851.10 KEG14923.1 - 7.7e-14 51.9 0.0 1.6e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KEG14923.1 - 3.2e-08 33.3 0.0 8.3e-08 31.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_3 PF13625.1 KEG14923.1 - 1.7e-07 31.0 0.0 7.5e-07 28.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KEG14923.1 - 2.1e-06 26.7 0.1 3.8e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 KEG14923.1 - 0.024 14.1 0.0 0.048 13.1 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase Inhibitor_I10 PF12559.3 KEG14923.1 - 2.1 8.6 4.0 2.4 8.4 0.1 2.6 2 0 0 2 2 2 0 Serine endopeptidase inhibitors PABP PF00658.13 KEG14924.1 - 2.7e-19 68.6 0.1 2.9e-19 68.4 0.1 1.0 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain Herpes_DNAp_acc PF04929.7 KEG14926.1 - 0.45 9.4 10.8 0.8 8.6 7.5 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor TraV PF09676.5 KEG14926.1 - 0.91 10.2 7.3 29 5.3 4.3 2.5 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) Pex14_N PF04695.8 KEG14926.1 - 3.6 7.6 7.1 27 4.8 2.5 3.1 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Rtf2 PF04641.7 KEG14926.1 - 5.4 6.1 12.4 10 5.2 8.6 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger PX PF00787.19 KEG14927.1 - 9.3e-06 25.4 0.0 2.5e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 PX domain TF_Zn_Ribbon PF08271.7 KEG14928.1 - 0.0038 16.5 0.5 0.0091 15.2 0.4 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Trm112p PF03966.11 KEG14928.1 - 0.033 14.5 0.2 0.063 13.6 0.2 1.5 1 0 0 1 1 1 0 Trm112p-like protein Inhibitor_I9 PF05922.11 KEG14929.1 - 0.0016 18.9 0.9 0.004 17.6 0.1 2.0 1 1 1 2 2 2 1 Peptidase inhibitor I9 RNase_Zc3h12a PF11977.3 KEG14930.1 - 0.001 18.9 0.0 0.0042 16.9 0.0 2.0 2 1 0 2 2 2 1 Zc3h12a-like Ribonuclease NYN domain Ribosomal_L37e PF01907.14 KEG14931.1 - 2.4e-26 91.2 7.4 4.4e-26 90.4 5.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e zf-P11 PF03854.9 KEG14931.1 - 0.023 14.1 0.5 0.039 13.4 0.3 1.3 1 0 0 1 1 1 0 P-11 zinc finger DZR PF12773.2 KEG14931.1 - 0.061 13.1 0.7 0.1 12.4 0.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_6 PF14599.1 KEG14931.1 - 0.085 12.6 0.4 0.14 11.9 0.3 1.3 1 0 0 1 1 1 0 Zinc-ribbon Circo_capsid PF02443.10 KEG14931.1 - 3.7 6.8 9.1 2.9 7.2 5.7 1.2 1 1 0 1 1 1 0 Circovirus capsid protein Glycos_transf_1 PF00534.15 KEG14932.1 - 1.7e-22 79.6 0.0 3.2e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KEG14932.1 - 9.8e-11 41.9 0.0 1.7e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pkinase PF00069.20 KEG14935.1 - 9.8e-44 149.4 0.0 1.5e-43 148.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG14935.1 - 6.4e-17 61.4 0.0 1.2e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG14935.1 - 2.7e-08 33.1 0.0 4.5e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 KEG14935.1 - 0.13 11.5 0.0 0.33 10.2 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL MMR_HSR1 PF01926.18 KEG14936.1 - 0.00026 20.9 0.0 0.00044 20.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KEG14936.1 - 0.027 14.4 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Miro PF08477.8 KEG14936.1 - 0.067 13.6 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein FeoB_N PF02421.13 KEG14936.1 - 0.08 12.2 0.1 0.76 9.0 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B FXa_inhibition PF14670.1 KEG14936.1 - 0.091 12.9 0.6 0.72 10.0 0.2 2.3 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site DUF830 PF05708.7 KEG14937.1 - 0.0018 18.2 0.0 0.052 13.5 0.0 2.3 2 0 0 2 2 2 2 Orthopoxvirus protein of unknown function (DUF830) zf-CCCH PF00642.19 KEG14938.1 - 0.0018 17.9 0.3 0.0018 17.9 0.2 2.4 2 1 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MMR_HSR1 PF01926.18 KEG14939.1 - 1.9e-10 40.6 0.0 4.6e-09 36.2 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 KEG14939.1 - 0.00013 21.2 0.0 0.00036 19.7 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KEG14939.1 - 0.006 16.7 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.13 KEG14939.1 - 0.011 15.0 0.0 0.036 13.3 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B Dynamin_N PF00350.18 KEG14939.1 - 0.022 14.5 0.0 1.8 8.3 0.0 2.5 2 0 0 2 2 2 0 Dynamin family AAA_17 PF13207.1 KEG14939.1 - 0.064 14.0 0.0 0.23 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain DivIVA PF05103.8 KEG14940.1 - 0.1 12.6 0.3 0.1 12.6 0.2 4.6 3 2 1 4 4 4 0 DivIVA protein DUF479 PF04336.7 KEG14940.1 - 0.17 12.0 1.6 44 4.2 0.4 3.6 3 0 0 3 3 3 0 Protein of unknown function, DUF479 DUF1479 PF07350.7 KEG14940.1 - 0.36 9.2 3.7 2 6.8 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1479) Herpes_BLRF2 PF05812.7 KEG14940.1 - 0.47 10.2 12.1 0.51 10.1 1.1 3.7 3 0 0 3 3 3 0 Herpesvirus BLRF2 protein Nsp1_C PF05064.8 KEG14940.1 - 2.7 7.6 13.3 0.99 9.0 0.4 3.2 3 1 1 4 4 4 0 Nsp1-like C-terminal region Methyltransf_4 PF02390.12 KEG14941.1 - 4.8e-35 120.4 0.0 5.5e-35 120.2 0.0 1.0 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KEG14941.1 - 1.8e-06 28.5 0.0 4e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEG14941.1 - 2.7e-05 23.7 0.0 5.2e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEG14941.1 - 0.0014 19.0 0.0 0.0027 18.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEG14941.1 - 0.0029 17.9 0.0 0.0051 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KEG14941.1 - 0.027 13.8 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_26 PF13659.1 KEG14941.1 - 0.07 13.1 0.0 0.11 12.5 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain ABC2_membrane_6 PF06182.6 KEG14942.1 - 0.017 14.7 0.9 0.019 14.5 0.7 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein HALZ PF02183.13 KEG14943.1 - 9.7e-07 28.4 2.7 2e-06 27.4 1.9 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper DivIVA PF05103.8 KEG14943.1 - 0.0018 18.2 1.4 0.0018 18.2 0.9 1.7 1 1 0 2 2 2 1 DivIVA protein Kinetocho_Slk19 PF12709.2 KEG14943.1 - 0.004 17.2 2.3 0.0049 16.9 1.6 1.2 1 0 0 1 1 1 1 Central kinetochore-associated DivIC PF04977.10 KEG14943.1 - 0.013 14.9 4.9 0.018 14.4 1.5 2.0 2 0 0 2 2 2 0 Septum formation initiator EcoEI_R_C PF08463.5 KEG14943.1 - 0.034 13.9 0.5 0.061 13.1 0.3 1.5 1 1 0 1 1 1 0 EcoEI R protein C-terminal DUF1640 PF07798.6 KEG14943.1 - 0.039 13.9 0.3 0.043 13.8 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Microtub_assoc PF07989.6 KEG14943.1 - 0.047 13.5 0.8 0.087 12.6 0.1 1.8 2 0 0 2 2 2 0 Microtubule associated Lzipper-MIP1 PF14389.1 KEG14943.1 - 0.058 13.5 1.6 0.058 13.5 1.1 1.6 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Dpy-30 PF05186.8 KEG14943.1 - 0.062 12.7 0.4 0.17 11.4 0.3 1.7 1 1 0 1 1 1 0 Dpy-30 motif Kinesin-relat_1 PF12711.2 KEG14943.1 - 0.067 13.5 1.4 0.08 13.3 0.1 1.7 2 0 0 2 2 2 0 Kinesin motor Mesothelin PF06060.7 KEG14943.1 - 0.11 10.4 0.0 0.13 10.2 0.0 1.1 1 0 0 1 1 1 0 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) Antimicrobial20 PF08256.6 KEG14943.1 - 0.13 12.5 1.0 0.32 11.4 0.7 1.7 1 0 0 1 1 1 0 Aurein-like antibiotic peptide Seadorna_VP6 PF07407.6 KEG14943.1 - 0.15 10.8 0.2 0.2 10.3 0.1 1.3 1 1 0 1 1 1 0 Seadornavirus VP6 protein DUF972 PF06156.8 KEG14943.1 - 0.27 11.6 3.0 0.51 10.7 0.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) FlaC_arch PF05377.6 KEG14943.1 - 0.28 11.0 2.4 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) WD40 PF00400.27 KEG14944.1 - 1.8e-18 65.6 13.8 6.7e-07 28.9 0.1 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat DUF4557 PF15101.1 KEG14944.1 - 0.072 12.9 2.0 0.12 12.1 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) TGS PF02824.16 KEG14948.1 - 2.5e-23 81.6 0.1 5.1e-23 80.6 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 KEG14948.1 - 7.1e-17 61.4 0.0 2.1e-16 59.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KEG14948.1 - 1.5e-09 37.3 0.0 2.9e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KEG14948.1 - 0.0012 18.6 0.0 0.19 11.5 0.0 2.5 2 0 0 2 2 2 1 Dynamin family Miro PF08477.8 KEG14948.1 - 0.0035 17.8 0.0 0.012 16.0 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 KEG14948.1 - 0.036 13.1 0.0 0.077 12.0 0.0 1.6 1 0 0 1 1 1 0 AIG1 family AAA_16 PF13191.1 KEG14948.1 - 0.036 14.0 0.0 0.075 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain SAC3_GANP PF03399.11 KEG14949.1 - 7e-30 104.1 0.1 1.2e-29 103.3 0.1 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family FMN_dh PF01070.13 KEG14950.1 - 1e-32 113.3 0.0 4e-23 81.8 0.0 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.20 KEG14950.1 - 6.3e-07 28.5 0.0 4.7e-05 22.4 0.0 2.7 2 2 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KEG14950.1 - 0.00028 19.9 1.2 0.00094 18.1 0.8 1.7 1 1 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 KEG14950.1 - 0.019 14.0 0.1 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase His_biosynth PF00977.16 KEG14950.1 - 0.079 12.2 0.0 0.21 10.8 0.0 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein Ank PF00023.25 KEG14951.1 - 1.8e-07 30.5 0.0 0.0013 18.4 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 KEG14951.1 - 3e-07 30.6 0.0 6.2e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEG14951.1 - 4.4e-05 23.8 0.0 0.041 14.4 0.0 3.5 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEG14951.1 - 5.8e-05 22.9 0.0 0.73 10.2 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Dynein_heavy PF03028.10 KEG14951.1 - 0.017 13.1 0.0 0.026 12.5 0.0 1.1 1 0 0 1 1 1 0 Dynein heavy chain and region D6 of dynein motor DUF4452 PF14618.1 KEG14951.1 - 0.062 13.1 0.1 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4452) GAS PF13851.1 KEG14951.1 - 0.13 11.4 1.1 0.19 10.9 0.8 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF1895 PF08988.5 KEG14951.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1895) Aa_trans PF01490.13 KEG14952.1 - 2.8e-48 164.4 24.9 3.1e-48 164.2 17.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Peptidase_M48 PF01435.13 KEG14953.1 - 8.1e-39 133.5 0.0 1.1e-38 133.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Erf4 PF10256.4 KEG14953.1 - 0.046 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family LRR_4 PF12799.2 KEG14957.1 - 5.7e-25 86.4 11.6 0.00018 21.0 0.1 10.6 2 1 8 12 12 12 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG14957.1 - 1.4e-20 72.7 10.2 0.0065 16.2 0.0 8.0 7 2 2 9 9 9 7 Leucine rich repeat LRR_6 PF13516.1 KEG14957.1 - 7.2e-15 53.3 19.9 0.13 12.4 0.0 11.4 12 1 2 14 14 14 6 Leucine Rich repeat LRR_5 PF13306.1 KEG14957.1 - 0.00036 20.2 2.9 6 6.5 0.2 4.7 4 2 0 4 4 4 2 Leucine rich repeats (6 copies) Ste50p-SAM PF09235.5 KEG14957.1 - 0.77 9.8 5.8 25 4.9 0.0 4.5 4 1 0 4 4 4 0 Ste50p, sterile alpha motif Pkinase PF00069.20 KEG14958.1 - 7e-61 205.6 0.0 9.2e-61 205.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG14958.1 - 1.2e-30 106.4 0.0 1.9e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KEG14958.1 - 0.006 15.6 0.0 0.0096 15.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KEG14958.1 - 0.02 13.8 0.0 0.034 13.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KEG14958.1 - 0.039 13.6 0.0 0.068 12.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family CitF PF04223.7 KEG14959.1 - 0.12 11.0 0.0 0.17 10.4 0.0 1.2 1 0 0 1 1 1 0 Citrate lyase, alpha subunit (CitF) Arm PF00514.18 KEG14960.1 - 1.2e-51 170.8 28.6 1.5e-10 40.4 0.1 17.0 17 0 0 17 17 17 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KEG14960.1 - 2.9e-07 30.6 18.6 0.007 16.6 0.2 7.2 3 2 2 5 5 5 2 HEAT repeats Arm_2 PF04826.8 KEG14960.1 - 1.9e-06 27.1 0.1 0.0027 16.8 0.0 4.9 4 1 2 6 6 6 2 Armadillo-like HEAT PF02985.17 KEG14960.1 - 9.4e-05 22.1 10.8 0.034 14.2 0.0 6.1 5 0 0 5 5 5 1 HEAT repeat E3_UbLigase_R4 PF13764.1 KEG14960.1 - 0.0024 15.8 0.1 0.16 9.8 0.0 2.6 2 0 0 2 2 2 1 E3 ubiquitin-protein ligase UBR4 HEAT_EZ PF13513.1 KEG14960.1 - 0.0032 17.9 19.2 0.42 11.1 0.0 6.5 7 0 0 7 7 7 3 HEAT-like repeat YcgR PF07317.7 KEG14960.1 - 0.064 13.0 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Flagellar regulator YcgR DUF383 PF04063.9 KEG14960.1 - 0.067 12.7 0.0 1.2e+02 2.0 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF383) Dicty_REP PF05086.7 KEG14960.1 - 3.3 5.3 6.8 4.8 4.8 4.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Utp14 PF04615.8 KEG14961.1 - 3.1e-71 240.5 61.1 3.1e-71 240.5 42.3 3.4 1 1 0 1 1 1 1 Utp14 protein DUF563 PF04577.9 KEG14964.1 - 0.00015 21.7 0.0 0.00038 20.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF563) RasGEF_N PF00618.15 KEG14964.1 - 0.04 14.0 0.4 7.8 6.6 0.0 2.7 2 0 0 2 2 2 0 RasGEF N-terminal motif LRR_9 PF14580.1 KEG14965.1 - 2.1e-21 76.2 0.9 2.4e-11 43.5 0.3 2.2 2 0 0 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.2 KEG14965.1 - 0.0024 17.4 4.3 0.19 11.4 0.2 3.4 2 1 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEG14965.1 - 0.054 13.5 5.9 42 4.7 0.1 4.5 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.1 KEG14965.1 - 0.098 12.4 6.0 0.77 9.5 0.0 3.0 2 1 1 3 3 3 0 Leucine rich repeat LRR_7 PF13504.1 KEG14965.1 - 1.2 9.5 3.2 1.1e+02 3.7 0.0 4.1 3 1 0 3 3 3 0 Leucine rich repeat DUF1936 PF09151.5 KEG14966.1 - 0.16 11.5 0.0 0.4 10.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1936) HSP70 PF00012.15 KEG14967.1 - 1.4e-08 33.1 0.0 2.3e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein Rtt106 PF08512.7 KEG14969.1 - 1.3e-14 53.8 0.0 1.2e-13 50.7 0.0 2.1 2 0 0 2 2 2 1 Histone chaperone Rttp106-like CDC45 PF02724.9 KEG14969.1 - 0.0028 15.7 29.5 0.0042 15.1 20.4 1.2 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.7 KEG14969.1 - 0.0028 15.6 30.8 0.0047 14.9 21.3 1.3 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.7 KEG14969.1 - 0.32 10.2 36.2 0.52 9.5 25.1 1.3 1 0 0 1 1 1 0 SDA1 Zip PF02535.17 KEG14969.1 - 0.57 9.1 12.2 1.2 8.0 8.4 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter YL1 PF05764.8 KEG14969.1 - 1.4 8.4 37.4 2.1 7.8 25.9 1.3 1 0 0 1 1 1 0 YL1 nuclear protein DUF2457 PF10446.4 KEG14969.1 - 2 7.0 45.5 0.34 9.5 28.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2457) Apt1 PF10351.4 KEG14969.1 - 9.3 4.9 18.3 14 4.3 12.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SecG PF03840.9 KEG14970.1 - 0.068 12.9 0.4 0.3 10.8 0.3 2.1 1 0 0 1 1 1 0 Preprotein translocase SecG subunit LRR_4 PF12799.2 KEG14971.1 - 1.1e-09 37.6 0.0 0.0006 19.3 0.0 4.6 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG14971.1 - 6.2e-07 29.0 0.2 0.00039 20.1 0.1 3.4 4 0 0 4 4 4 1 Leucine rich repeat LRR_1 PF00560.28 KEG14971.1 - 1.4e-05 24.5 3.0 0.26 11.4 0.0 5.2 4 1 1 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.1 KEG14971.1 - 0.00019 21.1 0.5 2.1 8.6 0.0 4.3 4 0 0 4 4 4 1 Leucine Rich repeat K_channel_TID PF07941.6 KEG14971.1 - 0.37 11.0 0.1 0.14 12.4 1.1 4.8 5 0 0 5 5 5 0 Potassium channel Kv1.4 tandem inactivation domain LRR_7 PF13504.1 KEG14971.1 - 0.73 10.2 9.8 11 6.7 0.1 4.6 6 0 0 6 6 6 0 Leucine rich repeat DUF3377 PF11857.3 KEG14971.1 - 5.2 6.7 6.1 2.9 7.5 1.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Pkinase PF00069.20 KEG14973.1 - 2.7e-73 246.3 1.0 3.4e-73 245.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG14973.1 - 4.3e-52 176.7 0.0 7.1e-52 176.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG14973.1 - 3.9e-08 32.5 0.0 1e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Kinase-like DUF3895 PF13034.1 KEG14973.1 - 0.23 10.9 1.2 12 5.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3895) WD40 PF00400.27 KEG14974.1 - 4.8e-16 57.9 16.0 6.7e-10 38.4 0.5 7.8 8 0 0 8 8 8 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KEG14974.1 - 0.001 17.9 0.2 5.6 5.6 0.0 4.4 5 1 1 6 6 6 2 Coatomer WD associated region TPR_7 PF13176.1 KEG14974.1 - 0.0051 16.5 5.0 2.8 7.9 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat Nic96 PF04097.9 KEG14974.1 - 0.0059 14.7 0.0 0.19 9.7 0.0 2.2 2 0 0 2 2 2 1 Nup93/Nic96 TPR_12 PF13424.1 KEG14974.1 - 0.014 15.2 3.5 3.1 7.8 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat BBS2_Mid PF14783.1 KEG14974.1 - 0.026 14.2 0.0 2.5 7.9 0.0 3.3 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Clathrin PF00637.15 KEG14974.1 - 0.047 13.2 1.5 4.7 6.8 0.0 3.5 2 1 1 4 4 4 0 Region in Clathrin and VPS TPR_14 PF13428.1 KEG14974.1 - 0.12 13.0 3.7 25 5.8 0.1 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-RING_3 PF14369.1 KEG14974.1 - 0.4 10.7 5.1 0.84 9.6 2.0 2.5 2 0 0 2 2 2 0 zinc-finger TPR_8 PF13181.1 KEG14974.1 - 0.46 10.3 4.1 4.7 7.2 0.1 4.0 5 0 0 5 5 3 0 Tetratricopeptide repeat DZR PF12773.2 KEG14974.1 - 0.86 9.4 6.7 0.34 10.7 0.2 2.9 2 0 0 2 2 2 0 Double zinc ribbon TPR_11 PF13414.1 KEG14974.1 - 0.92 9.1 7.2 47 3.7 0.0 4.5 4 0 0 4 4 4 0 TPR repeat TPR_2 PF07719.12 KEG14974.1 - 1.9 8.6 18.9 0.19 11.7 0.2 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat zf-CCHC_3 PF13917.1 KEG14974.1 - 3 7.6 6.1 44 3.9 3.1 2.6 2 0 0 2 2 2 0 Zinc knuckle SNAP PF14938.1 KEG14974.1 - 4.2 6.4 7.4 3.5 6.6 3.0 2.1 2 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP DUF4207 PF13904.1 KEG14976.1 - 0.53 9.6 13.7 0.017 14.5 4.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) DUF898 PF05987.8 KEG14976.1 - 0.79 8.5 5.8 0.054 12.3 0.4 1.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) CLAMP PF14769.1 KEG14978.1 - 1.1e-30 105.7 0.9 1.8e-30 105.0 0.6 1.4 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 HSBP1 PF06825.7 KEG14978.1 - 0.016 14.7 0.3 0.034 13.7 0.2 1.5 1 0 0 1 1 1 0 Heat shock factor binding protein 1 YtzH PF14165.1 KEG14978.1 - 0.028 14.6 0.2 0.069 13.3 0.1 1.8 1 1 0 1 1 1 0 YtzH-like protein Syntaxin PF00804.20 KEG14978.1 - 0.72 10.0 4.5 3.8 7.7 3.1 2.1 2 0 0 2 2 2 0 Syntaxin Prp19 PF08606.6 KEG14979.1 - 0.098 12.4 0.7 8 6.2 0.0 2.8 3 0 0 3 3 3 0 Prp19/Pso4-like Ribonuclease_3 PF00636.21 KEG14979.1 - 0.15 12.5 0.0 1.1 9.7 0.0 2.3 1 1 0 1 1 1 0 Ribonuclease III domain WHIM1 PF15612.1 KEG14980.1 - 0.0081 16.0 0.2 0.045 13.6 0.1 2.4 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM3 PF15614.1 KEG14980.1 - 0.0086 15.8 0.0 0.05 13.4 0.0 2.3 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 3 DDT PF02791.12 KEG14980.1 - 0.011 15.4 0.1 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 DDT domain DUF1512 PF07431.7 KEG14980.1 - 0.011 14.4 0.3 0.02 13.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) WHIM2 PF15613.1 KEG14980.1 - 0.022 14.7 0.1 0.049 13.5 0.1 1.5 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 2 Daxx PF03344.10 KEG14980.1 - 0.071 11.5 30.3 0.16 10.4 21.0 1.5 1 0 0 1 1 1 0 Daxx Family hDGE_amylase PF14701.1 KEG14980.1 - 0.26 10.1 3.1 0.46 9.3 2.1 1.3 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Merozoite_SPAM PF07133.6 KEG14980.1 - 2 8.2 42.2 0.083 12.7 1.5 2.7 3 0 0 3 3 3 0 Merozoite surface protein (SPAM) Ribosomal_L24e PF01246.15 KEG14981.1 - 1.6e-14 53.4 0.6 1.6e-14 53.4 0.4 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e HORMA PF02301.13 KEG14982.1 - 1.6e-51 174.7 0.0 2.2e-51 174.2 0.0 1.2 1 0 0 1 1 1 1 HORMA domain CorA PF01544.13 KEG14984.1 - 2.5e-10 39.8 0.0 4.8e-09 35.6 0.0 2.4 3 0 0 3 3 3 1 CorA-like Mg2+ transporter protein DUF998 PF06197.8 KEG14984.1 - 0.015 14.6 0.7 0.024 13.9 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF998) Exo_endo_phos PF03372.18 KEG14985.1 - 6.6e-08 32.7 0.0 6.5e-07 29.5 0.0 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Memo PF01875.12 KEG14986.1 - 2.3e-62 210.3 0.0 2.8e-62 210.1 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein CorA PF01544.13 KEG14987.1 - 4e-09 35.9 1.1 2.8e-08 33.1 0.8 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein COQ7 PF03232.8 KEG14989.1 - 0.00036 20.0 0.0 0.00049 19.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Glyco_transf_22 PF03901.12 KEG14990.1 - 5.7e-99 331.9 27.6 7.3e-99 331.5 19.1 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PP2C PF00481.16 KEG14993.1 - 4e-16 59.1 0.0 6.7e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C HisK_N PF09385.5 KEG14994.1 - 0.079 12.5 0.0 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase N terminal Ribosomal_S4 PF00163.14 KEG14995.1 - 9.8e-28 96.3 0.5 2e-27 95.3 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 KEG14995.1 - 1.5e-12 46.6 0.3 3.2e-12 45.6 0.2 1.6 1 0 0 1 1 1 1 S4 domain Pkinase PF00069.20 KEG14996.1 - 2e-44 151.6 0.0 2.1e-31 109.0 0.0 3.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEG14996.1 - 2.8e-23 82.3 0.0 2.9e-16 59.3 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase CDK2AP PF09806.4 KEG14996.1 - 0.058 13.6 1.9 0.56 10.4 0.6 2.5 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Kinase-like PF14531.1 KEG14996.1 - 0.45 9.4 0.0 3.4 6.5 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Macoilin PF09726.4 KEG14996.1 - 1.2 7.2 2.5 1.7 6.8 1.7 1.3 1 0 0 1 1 1 0 Transmembrane protein EF-hand_1 PF00036.27 KEG15000.1 - 2.8e-15 54.3 0.7 0.0026 16.9 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 KEG15000.1 - 1.3e-14 54.0 0.2 1.5e-07 31.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KEG15000.1 - 3.7e-12 45.0 2.8 0.0029 17.3 0.0 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 KEG15000.1 - 1.2e-10 40.2 0.7 0.0075 15.5 0.0 3.7 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 KEG15000.1 - 1.4e-09 37.4 0.8 0.0086 15.6 0.0 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_10 PF14788.1 KEG15000.1 - 0.1 12.2 0.0 15 5.3 0.0 2.9 2 1 0 2 2 2 0 EF hand HECT PF00632.20 KEG15001.1 - 2.2e-55 188.0 0.0 3.4e-55 187.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.23 KEG15001.1 - 2.7e-35 121.1 2.0 3.3e-14 53.0 0.0 3.7 3 0 0 3 3 3 3 SPRY domain Laminin_G_3 PF13385.1 KEG15001.1 - 8e-13 48.9 1.5 1.1e-05 25.6 0.0 3.1 2 1 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily Serglycin PF04360.7 KEG15001.1 - 0.018 14.7 0.3 0.047 13.4 0.2 1.6 1 0 0 1 1 1 0 Serglycin Ran_BP1 PF00638.13 KEG15002.1 - 1.1e-26 93.3 0.6 1.3e-26 93.0 0.4 1.1 1 0 0 1 1 1 1 RanBP1 domain Lactamase_B_2 PF12706.2 KEG15003.1 - 2.9e-08 33.5 0.4 9.3e-08 31.8 0.2 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KEG15003.1 - 1e-07 31.8 1.9 6.6e-07 29.1 1.3 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Toxin_9 PF02819.10 KEG15004.1 - 0.023 14.7 1.1 0.042 13.9 0.8 1.3 1 0 0 1 1 1 0 Spider toxin PIN_4 PF13638.1 KEG15005.1 - 0.00023 21.2 0.0 0.00028 20.9 0.0 1.1 1 0 0 1 1 1 1 PIN domain AAA PF00004.24 KEG15006.1 - 3.6e-14 53.0 0.0 1.1e-13 51.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEG15006.1 - 0.0023 17.9 1.2 0.023 14.6 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain IQ PF00612.22 KEG15006.1 - 0.0064 16.0 0.9 0.0064 16.0 0.6 3.4 3 0 0 3 3 3 1 IQ calmodulin-binding motif AAA_25 PF13481.1 KEG15006.1 - 0.011 15.2 0.1 0.12 11.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain OmpA PF00691.15 KEG15006.1 - 0.019 15.3 0.2 1.3 9.4 0.1 2.9 2 0 0 2 2 2 0 OmpA family AAA_33 PF13671.1 KEG15006.1 - 0.019 14.8 2.6 0.072 12.9 0.0 3.2 3 1 0 3 3 3 0 AAA domain AAA_17 PF13207.1 KEG15006.1 - 0.027 15.2 0.9 0.33 11.7 0.0 3.0 3 1 0 3 3 3 0 AAA domain cobW PF02492.14 KEG15006.1 - 0.086 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Diacid_rec PF05651.8 KEG15007.1 - 0.11 11.9 0.4 0.15 11.5 0.3 1.2 1 0 0 1 1 1 0 Putative sugar diacid recognition E1-E2_ATPase PF00122.15 KEG15008.1 - 3.2e-19 68.9 0.0 1.2e-18 67.0 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KEG15008.1 - 2e-12 47.9 0.2 7e-11 42.9 0.1 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEG15008.1 - 3.8e-11 42.7 0.0 2.1e-09 37.2 0.0 2.4 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KEG15008.1 - 8e-11 42.4 0.1 2e-10 41.1 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KEG15008.1 - 0.051 13.1 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase RRM_1 PF00076.17 KEG15009.1 - 1.1e-07 31.4 0.0 4.1e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG15009.1 - 2.3e-06 27.4 0.0 0.00013 21.8 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG15009.1 - 0.078 12.8 0.0 14 5.5 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GHMP_kinases_C PF08544.8 KEG15009.1 - 0.092 12.9 0.3 15 5.8 0.0 2.4 2 0 0 2 2 2 0 GHMP kinases C terminal PBP1_TM PF14812.1 KEG15009.1 - 0.92 9.8 6.4 1.5 9.1 4.4 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Dicty_REP PF05086.7 KEG15010.1 - 0.022 12.5 1.1 0.035 11.8 0.8 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 KEG15010.1 - 7.2 6.3 19.6 0.072 12.8 7.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Gtr1_RagA PF04670.7 KEG15011.1 - 4.8e-90 300.7 0.0 7.1e-90 300.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 KEG15011.1 - 5.3e-06 25.9 0.0 1.3e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Ras family Arf PF00025.16 KEG15011.1 - 0.00016 20.9 0.0 0.00048 19.4 0.0 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 KEG15011.1 - 0.011 16.2 0.0 0.024 15.1 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Metallophos PF00149.23 KEG15012.1 - 2.7e-29 102.0 0.0 3.9e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UQ_con PF00179.21 KEG15013.1 - 6.2e-16 58.0 0.0 6.5e-16 58.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KEG15013.1 - 0.00075 19.3 0.0 0.00081 19.2 0.0 1.2 1 0 0 1 1 1 1 RWD domain Tcp10_C PF07202.8 KEG15014.1 - 8.2e-30 103.6 0.1 1.3e-29 102.9 0.0 1.4 1 0 0 1 1 1 1 T-complex protein 10 C-terminus Spt20 PF12090.3 KEG15015.1 - 0.0047 16.3 0.8 0.0047 16.3 0.6 2.3 2 0 0 2 2 2 1 Spt20 family DUF3439 PF11921.3 KEG15015.1 - 0.065 12.9 1.1 0.17 11.6 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) ATP-synt_G PF04718.10 KEG15015.1 - 2.4 8.8 9.3 0.19 12.3 0.2 3.9 3 0 0 3 3 3 0 Mitochondrial ATP synthase g subunit Kinesin PF00225.18 KEG15016.1 - 1.5e-91 306.6 0.0 3.6e-91 305.3 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain SAM_1 PF00536.25 KEG15016.1 - 3.3e-05 23.9 2.6 5.8e-05 23.1 0.5 2.3 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KEG15016.1 - 0.00018 21.2 0.5 0.00048 19.9 0.3 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CDC50 PF03381.10 KEG15017.1 - 4.2e-84 282.0 0.1 5.8e-84 281.5 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Lipocalin_4 PF13648.1 KEG15017.1 - 0.066 13.8 0.1 0.15 12.6 0.1 1.5 1 0 0 1 1 1 0 Lipocalin-like domain Rep_fac-A_3 PF08661.6 KEG15020.1 - 3.9e-08 33.1 0.0 4.9e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Replication factor A protein 3 BHD_3 PF10405.4 KEG15021.1 - 5.8e-19 67.5 0.0 1.4e-18 66.3 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.10 KEG15021.1 - 2.8e-18 65.7 0.1 8.4e-18 64.1 0.1 1.8 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_1 PF10403.4 KEG15021.1 - 3.2e-14 52.1 0.4 9.7e-14 50.6 0.0 2.0 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 KEG15021.1 - 8.4e-08 32.4 0.1 4.6e-07 30.0 0.0 2.5 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 peroxidase PF00141.18 KEG15022.1 - 2.4e-05 23.9 0.0 3.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Acyl_transf_1 PF00698.16 KEG15023.1 - 4.1e-21 75.6 0.0 1.4e-20 73.8 0.0 1.8 2 1 0 2 2 2 1 Acyl transferase domain DUF4058 PF13267.1 KEG15027.1 - 0.023 13.8 1.8 0.084 11.9 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4058) FYVE PF01363.16 KEG15028.1 - 1.1e-20 73.3 8.6 1.9e-20 72.5 6.0 1.4 1 0 0 1 1 1 1 FYVE zinc finger DM PF00751.13 KEG15028.1 - 0.019 14.4 4.7 0.036 13.6 3.3 1.4 1 0 0 1 1 1 0 DM DNA binding domain Elf1 PF05129.8 KEG15028.1 - 0.03 14.0 3.4 0.065 12.9 2.4 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like FYVE_2 PF02318.11 KEG15028.1 - 0.16 11.8 6.5 0.056 13.3 2.2 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger GATA PF00320.22 KEG15028.1 - 0.23 10.8 3.7 11 5.5 0.0 3.2 2 1 0 2 2 2 0 GATA zinc finger Ribosomal_L37e PF01907.14 KEG15028.1 - 0.93 9.3 6.8 2.2 8.1 4.7 1.6 1 0 0 1 1 1 0 Ribosomal protein L37e zf-RING_5 PF14634.1 KEG15028.1 - 7.5 6.3 11.7 14 5.5 5.0 2.4 2 0 0 2 2 2 0 zinc-RING finger domain Ribosomal_L32p PF01783.18 KEG15028.1 - 9.7 6.4 8.7 1.2 9.3 2.1 2.3 2 1 0 2 2 2 0 Ribosomal L32p protein family Milton PF12448.3 KEG15029.1 - 0.0013 18.9 1.2 0.0013 18.9 0.8 2.4 2 1 1 3 3 3 1 Kinesin associated protein Mito_fiss_reg PF05308.6 KEG15029.1 - 1 8.7 5.3 0.34 10.2 0.6 2.3 1 1 1 2 2 2 0 Mitochondrial fission regulator CAP_N PF01213.14 KEG15029.1 - 1.4 8.0 3.5 0.57 9.4 0.5 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal SMC_N PF02463.14 KEG15031.1 - 1.8e-56 190.8 0.0 5.2e-55 186.0 0.0 3.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KEG15031.1 - 1.7e-30 105.4 0.0 7.6e-30 103.3 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KEG15031.1 - 3.4e-15 56.7 0.2 1.9e-07 31.3 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KEG15031.1 - 3.7e-09 35.9 0.0 7.5e-09 34.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 KEG15031.1 - 9.5e-06 26.0 74.3 1.4e-05 25.5 27.4 5.6 3 2 0 3 3 3 1 AAA domain AAA_5 PF07728.9 KEG15031.1 - 0.0037 16.9 3.9 0.24 11.1 0.0 3.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KEG15031.1 - 0.029 13.7 3.3 0.075 12.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain DUF2939 PF11159.3 KEG15031.1 - 0.26 11.4 3.9 2.2 8.4 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2939) AAA_15 PF13175.1 KEG15031.1 - 0.27 10.2 16.3 1.7e+02 1.0 13.7 3.1 2 1 0 2 2 2 0 AAA ATPase domain Reo_sigmaC PF04582.7 KEG15031.1 - 7 5.7 16.6 4.4 6.3 0.2 5.1 5 1 1 6 6 6 0 Reovirus sigma C capsid protein KH_1 PF00013.24 KEG15033.1 - 7.3e-06 25.5 0.4 2.5e-05 23.8 0.1 2.0 2 0 0 2 2 2 1 KH domain Reo_sigmaC PF04582.7 KEG15034.1 - 0.011 14.9 1.3 2.9 7.0 0.0 2.9 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 KEG15034.1 - 0.12 12.1 3.0 12 5.6 0.5 3.6 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tht1 PF04163.7 KEG15034.1 - 0.22 9.9 0.0 0.36 9.1 0.0 1.3 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein PAT1 PF09770.4 KEG15034.1 - 0.69 8.0 30.1 1.5 7.0 20.8 1.6 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CRAL_TRIO PF00650.15 KEG15035.1 - 7.5e-24 84.0 0.5 2.1e-23 82.5 0.2 1.7 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KEG15035.1 - 9.1e-12 44.9 0.5 2.6e-11 43.4 0.3 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain zf-piccolo PF05715.8 KEG15035.1 - 2.7 8.0 5.8 1.5 8.8 0.6 2.3 2 0 0 2 2 2 0 Piccolo Zn-finger MatE PF01554.13 KEG15036.1 - 1.1e-37 129.1 29.3 9e-21 74.1 8.5 2.2 2 0 0 2 2 2 2 MatE MatE PF01554.13 KEG15037.1 - 3.4e-30 104.8 29.9 3.1e-19 69.1 5.9 2.7 2 1 0 2 2 2 2 MatE YGGT PF02325.12 KEG15037.1 - 0.11 12.4 3.7 0.27 11.2 0.2 2.7 2 0 0 2 2 2 0 YGGT family FUSC_2 PF13515.1 KEG15038.1 - 2.1e-05 24.4 3.6 2.1e-05 24.4 2.5 3.1 2 1 1 3 3 3 1 Fusaric acid resistance protein-like XPG_N PF00752.12 KEG15039.1 - 1.8e-21 76.2 0.0 3.6e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 KEG15039.1 - 8.4e-20 70.6 1.3 9.8e-20 70.4 0.1 1.8 2 0 0 2 2 2 1 XPG I-region XPG_I_2 PF12813.2 KEG15039.1 - 5.1e-11 42.5 0.4 1e-10 41.5 0.3 1.5 1 0 0 1 1 1 1 XPG domain containing Methyltransf_23 PF13489.1 KEG15040.1 - 3e-23 82.3 0.1 4.1e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEG15040.1 - 3.4e-12 46.6 0.0 1.2e-11 44.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEG15040.1 - 3.4e-07 30.6 0.0 1.2e-06 28.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEG15040.1 - 6.1e-07 30.0 0.2 1.7e-06 28.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEG15040.1 - 4.1e-05 23.2 0.0 0.00013 21.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEG15040.1 - 0.0022 18.0 0.3 0.0076 16.2 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEG15040.1 - 0.028 14.7 0.0 0.45 10.9 0.0 2.6 3 0 0 3 3 3 0 Methyltransferase domain Pro_isomerase PF00160.16 KEG15041.1 - 1.4e-30 106.5 0.0 1.6e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3659 PF12396.3 KEG15041.1 - 0.1 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) NifU_N PF01592.11 KEG15042.1 - 7.3e-46 155.2 0.0 9.4e-46 154.8 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain DUF1002 PF06207.6 KEG15043.1 - 0.093 12.0 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) DUF2796 PF10986.3 KEG15043.1 - 0.45 10.4 2.3 0.67 9.9 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Cwf_Cwc_15 PF04889.7 KEG15043.1 - 0.65 9.6 5.2 0.9 9.1 3.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.3 KEG15043.1 - 0.66 9.8 13.0 0.85 9.5 9.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.7 KEG15043.1 - 8.2 4.2 8.9 10 3.9 6.2 1.1 1 0 0 1 1 1 0 Nop14-like family DZR PF12773.2 KEG15045.1 - 0.00043 20.0 95.1 0.0094 15.7 5.1 9.1 6 3 1 7 7 7 6 Double zinc ribbon NDUF_B7 PF05676.8 KEG15046.1 - 1.5e-05 24.2 0.3 2.4e-05 23.6 0.2 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) NAD_binding_4 PF07993.7 KEG15047.1 - 7.8e-64 214.9 0.0 1e-63 214.5 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.14 KEG15047.1 - 1e-10 41.7 0.1 2.2e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KEG15047.1 - 2.3e-07 30.4 0.0 3.2e-06 26.7 0.0 2.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KEG15047.1 - 7.8e-05 21.6 0.1 0.022 13.6 0.1 2.3 2 0 0 2 2 2 2 RmlD substrate binding domain 3Beta_HSD PF01073.14 KEG15047.1 - 0.0026 16.5 2.3 0.88 8.2 2.0 2.8 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KEG15047.1 - 0.0048 15.8 0.1 0.14 11.0 0.1 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Kei1 PF08552.6 KEG15047.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Amastin PF07344.6 KEG15049.1 - 1.1e-07 31.5 4.3 1.1e-07 31.5 3.0 1.8 1 1 1 2 2 2 1 Amastin surface glycoprotein SHD1 PF03983.7 KEG15049.1 - 0.0072 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 Ni_hydr_CYTB PF01292.15 KEG15049.1 - 0.1 11.9 2.5 0.19 11.1 1.6 1.4 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 FAD_binding_2 PF00890.19 KEG15050.1 - 1.1e-114 383.4 1.1 1.1e-114 383.4 0.8 1.6 2 0 0 2 2 2 1 FAD binding domain Succ_DH_flav_C PF02910.15 KEG15050.1 - 1.1e-41 141.6 1.1 1.6e-41 141.1 0.8 1.2 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term DAO PF01266.19 KEG15050.1 - 2.4e-05 23.4 0.3 0.021 13.7 0.1 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.12 KEG15050.1 - 0.0001 21.4 0.1 0.038 13.0 0.1 3.0 3 0 0 3 3 3 1 Thi4 family Pyr_redox_2 PF07992.9 KEG15050.1 - 0.00019 21.3 0.1 0.011 15.6 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KEG15050.1 - 0.0027 16.6 2.6 0.1 11.4 1.7 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 KEG15050.1 - 0.015 13.7 0.2 0.032 12.6 0.1 1.5 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.7 KEG15050.1 - 0.023 13.6 2.4 1 8.2 0.4 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein GST_C_2 PF13410.1 KEG15051.1 - 1.4e-06 28.0 0.0 2.7e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KEG15051.1 - 0.00064 20.1 0.0 0.0012 19.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.4 KEG15052.1 - 2.3e-06 27.7 0.0 6e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_3 PF14497.1 KEG15052.1 - 0.00019 21.8 0.0 0.00084 19.7 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KEG15052.1 - 0.012 15.4 0.0 0.06 13.2 0.0 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF3175 PF11373.3 KEG15052.1 - 0.013 15.4 0.3 0.042 13.8 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3175) GST_C_2 PF13410.1 KEG15053.1 - 1.6e-08 34.2 0.0 3.2e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KEG15053.1 - 1.4e-06 28.6 0.0 2.3e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.4 KEG15053.1 - 3.1e-06 27.3 0.0 5.4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_3 PF13417.1 KEG15053.1 - 1.5e-05 25.1 0.0 5e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KEG15053.1 - 0.00012 22.0 0.0 0.00029 20.7 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KEG15053.1 - 0.047 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain RUN PF02759.14 KEG15054.1 - 0.047 13.4 0.1 0.097 12.4 0.0 1.5 1 0 0 1 1 1 0 RUN domain UBA PF00627.26 KEG15055.1 - 3.7e-07 29.7 0.0 6.3e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain Rhomboid PF01694.17 KEG15055.1 - 0.00015 21.7 0.7 0.0003 20.8 0.5 1.6 1 1 0 1 1 1 1 Rhomboid family CUE PF02845.11 KEG15055.1 - 0.0012 18.3 0.0 0.0025 17.2 0.0 1.6 1 0 0 1 1 1 1 CUE domain DUF1751 PF08551.5 KEG15055.1 - 0.022 15.0 0.8 0.043 14.1 0.0 1.8 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) MutL_C PF08676.6 KEG15061.1 - 0.0044 16.6 0.0 0.028 14.0 0.0 2.3 3 0 0 3 3 3 1 MutL C terminal dimerisation domain Pkinase PF00069.20 KEG15062.1 - 9.4e-30 103.6 0.0 2.7e-17 62.7 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEG15062.1 - 1.3e-07 31.0 0.0 0.001 18.2 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Pox_E2-like PF04497.7 KEG15062.1 - 0.37 8.7 0.0 0.53 8.2 0.0 1.1 1 0 0 1 1 1 0 Poxviridae protein 60KD_IMP PF02096.15 KEG15064.1 - 0.0011 18.7 0.3 0.064 12.9 0.0 2.2 2 0 0 2 2 2 2 60Kd inner membrane protein APG6 PF04111.7 KEG15065.1 - 0.011 14.7 1.0 0.017 14.1 0.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 SlyX PF04102.7 KEG15065.1 - 0.018 15.4 3.9 0.13 12.6 1.6 2.5 2 0 0 2 2 2 0 SlyX Cep57_CLD_2 PF14197.1 KEG15065.1 - 0.022 14.6 3.4 0.051 13.5 2.4 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 IncA PF04156.9 KEG15065.1 - 0.024 14.2 2.9 0.053 13.1 2.0 1.5 1 0 0 1 1 1 0 IncA protein Spc7 PF08317.6 KEG15065.1 - 0.029 13.0 1.2 0.043 12.4 0.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Cep57_MT_bd PF06657.8 KEG15065.1 - 0.041 13.8 1.2 0.096 12.6 0.8 1.7 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Prot_inhib_II PF02428.10 KEG15065.1 - 0.061 13.3 1.1 0.17 11.9 0.8 1.7 1 0 0 1 1 1 0 Potato type II proteinase inhibitor family DivIC PF04977.10 KEG15065.1 - 0.12 11.9 1.7 0.23 10.9 1.2 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF2205 PF10224.4 KEG15065.1 - 0.21 11.1 2.0 0.49 9.9 1.4 1.6 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) Cytochrom_c3_2 PF14537.1 KEG15065.1 - 3.2 8.1 7.5 15 6.0 1.6 3.1 2 0 0 2 2 2 0 Cytochrome c3 KfrA_N PF11740.3 KEG15065.1 - 7.8 6.9 11.8 0.48 10.8 3.4 2.5 3 0 0 3 3 2 0 Plasmid replication region DNA-binding N-term Methyltransf_16 PF10294.4 KEG15066.1 - 2.5e-22 79.1 0.0 2.6e-17 62.7 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 KEG15066.1 - 0.00025 21.5 0.3 0.00087 19.8 0.1 2.0 1 1 1 2 2 2 1 Methyltransferase domain PrmA PF06325.8 KEG15066.1 - 0.0092 15.1 0.1 0.015 14.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 KEG15066.1 - 0.012 15.5 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KEG15066.1 - 0.014 14.7 0.1 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.7 KEG15066.1 - 0.13 12.7 0.0 7.2 7.1 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Myb_DNA-binding PF00249.26 KEG15067.1 - 3.2e-16 59.0 2.3 1.5e-08 34.5 0.1 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KEG15067.1 - 3.2e-15 55.9 5.3 7.9e-08 32.2 0.2 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 KEG15067.1 - 0.003 17.6 0.3 4.1 7.6 0.0 3.3 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain PBP1_TM PF14812.1 KEG15067.1 - 0.59 10.4 15.5 0.23 11.8 0.4 3.4 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal IMPDH PF00478.20 KEG15069.1 - 5.2e-129 430.1 2.1 6e-129 429.9 1.4 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 KEG15069.1 - 7.8e-16 57.6 0.1 1.6e-06 27.7 0.1 2.8 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 KEG15069.1 - 7.8e-07 28.2 4.1 1.7e-06 27.1 2.8 1.6 1 1 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 KEG15069.1 - 7.9e-06 25.2 10.1 0.0014 17.8 3.0 3.0 2 1 1 3 3 3 2 Nitronate monooxygenase His_biosynth PF00977.16 KEG15069.1 - 7.2e-05 22.1 1.9 0.013 14.8 0.1 2.2 1 1 1 2 2 2 2 Histidine biosynthesis protein PcrB PF01884.12 KEG15069.1 - 0.00019 20.7 6.5 0.0094 15.2 0.0 3.4 2 1 1 3 3 3 1 PcrB family ThiG PF05690.9 KEG15069.1 - 0.0018 17.3 0.3 0.0018 17.3 0.2 2.1 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG DHO_dh PF01180.16 KEG15069.1 - 0.0022 17.0 2.9 0.063 12.2 0.2 2.3 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase Glu_synthase PF01645.12 KEG15069.1 - 0.0032 16.4 1.2 0.0055 15.6 0.8 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Lysine_decarbox PF03641.9 KEG15070.1 - 2.6e-29 101.7 0.7 4.2e-29 101.0 0.5 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase ABM PF03992.11 KEG15070.1 - 4.4e-10 39.4 0.1 1.6e-09 37.6 0.1 2.0 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase MbeD_MobD PF04899.7 KEG15070.1 - 0.13 12.1 1.4 0.31 10.9 0.1 2.2 2 0 0 2 2 2 0 MbeD/MobD like Cortex-I_coil PF09304.5 KEG15071.1 - 3.5e-05 23.7 7.4 3.5e-05 23.7 5.1 4.3 2 1 2 4 4 4 1 Cortexillin I, coiled coil DASH_Ask1 PF08655.5 KEG15071.1 - 0.12 12.1 0.6 22 4.9 0.0 3.0 2 1 0 2 2 2 0 DASH complex subunit Ask1 Baculo_PEP_C PF04513.7 KEG15071.1 - 1.2 8.9 6.9 17 5.2 0.1 3.9 1 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus MMPL PF03176.10 KEG15071.1 - 7.8 5.1 11.0 3.4 6.2 1.4 2.4 2 1 0 2 2 2 0 MMPL family Kinesin PF00225.18 KEG15072.1 - 2.5e-105 351.8 0.0 9e-105 350.0 0.0 2.0 1 0 0 1 1 1 1 Kinesin motor domain Transposase_22 PF02994.9 KEG15072.1 - 0.00082 17.9 10.6 0.00082 17.9 7.3 3.3 2 1 1 3 3 3 1 L1 transposable element Filament PF00038.16 KEG15072.1 - 0.0038 16.7 5.6 0.0038 16.7 3.9 4.8 2 2 2 4 4 4 2 Intermediate filament protein HYR PF02494.11 KEG15072.1 - 0.034 14.1 0.2 0.17 11.8 0.0 2.3 2 0 0 2 2 2 0 HYR domain Reo_sigmaC PF04582.7 KEG15072.1 - 1.2 8.2 19.0 0.2 10.8 1.4 3.7 2 2 1 3 3 3 0 Reovirus sigma C capsid protein Spc42p PF11544.3 KEG15072.1 - 1.5 8.7 15.5 0.045 13.6 2.5 3.7 2 1 1 3 3 3 0 Spindle pole body component Spc42p ApoO PF09769.4 KEG15072.1 - 2.2 7.9 10.9 2.7 7.6 2.0 3.0 2 1 0 3 3 3 0 Apolipoprotein O Seryl_tRNA_N PF02403.17 KEG15072.1 - 8.8 6.4 39.5 1.2 9.1 2.0 5.8 3 2 3 6 6 6 0 Seryl-tRNA synthetase N-terminal domain RRM_5 PF13893.1 KEG15073.1 - 0.0041 16.9 0.0 0.74 9.7 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEG15073.1 - 0.013 15.1 0.0 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tropomyosin_1 PF12718.2 KEG15073.1 - 0.057 13.2 7.7 0.045 13.5 3.1 2.3 2 0 0 2 2 2 0 Tropomyosin like RRM_6 PF14259.1 KEG15073.1 - 0.085 12.8 0.0 0.48 10.4 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Elf-1_N PF12310.3 KEG15073.1 - 0.087 12.7 3.1 0.13 12.2 0.6 2.4 2 0 0 2 2 2 0 Transcription factor protein N terminal Tropomyosin PF00261.15 KEG15073.1 - 0.095 11.7 8.0 0.016 14.3 2.8 1.7 2 0 0 2 2 2 0 Tropomyosin Nsp1_C PF05064.8 KEG15073.1 - 0.32 10.6 3.5 0.56 9.8 1.3 2.2 2 0 0 2 2 2 0 Nsp1-like C-terminal region HAUS-augmin3 PF14932.1 KEG15073.1 - 0.33 10.0 8.7 0.14 11.3 2.4 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF2205 PF10224.4 KEG15073.1 - 0.42 10.2 4.1 15 5.2 0.1 3.1 2 1 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF1192 PF06698.6 KEG15073.1 - 0.59 9.9 5.7 3.1 7.6 1.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) G-patch PF01585.18 KEG15074.1 - 4.6e-13 48.7 0.2 8.1e-13 47.9 0.1 1.5 1 0 0 1 1 1 1 G-patch domain Nha1_C PF08619.5 KEG15074.1 - 0.0002 20.7 2.1 0.0002 20.7 1.4 1.1 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus G-patch_2 PF12656.2 KEG15074.1 - 0.0023 17.7 0.2 0.0023 17.7 0.1 2.3 2 1 0 3 3 3 1 DExH-box splicing factor binding site Gag_spuma PF03276.9 KEG15074.1 - 0.0036 15.7 0.5 0.0043 15.4 0.3 1.0 1 0 0 1 1 1 1 Spumavirus gag protein DUF755 PF05501.6 KEG15074.1 - 0.0068 16.4 9.2 0.01 15.9 6.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF755) SR-25 PF10500.4 KEG15074.1 - 0.013 14.9 13.8 0.019 14.4 9.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Sporozoite_P67 PF05642.6 KEG15074.1 - 0.031 12.1 2.5 0.03 12.2 1.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nucleo_P87 PF07267.6 KEG15074.1 - 0.036 12.7 2.8 0.041 12.5 1.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF2151 PF10221.4 KEG15074.1 - 0.11 10.7 2.4 0.13 10.3 1.7 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator PGA2 PF07543.7 KEG15074.1 - 0.61 9.8 4.3 0.87 9.3 3.0 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 Pkinase PF00069.20 KEG15076.1 - 2.6e-56 190.6 0.0 3e-56 190.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG15076.1 - 1.7e-21 76.4 0.0 2.4e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 KEG15076.1 - 0.0011 18.6 0.1 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 KEG15076.1 - 0.0015 18.3 0.1 0.0061 16.3 0.0 1.8 1 1 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KEG15076.1 - 0.089 11.4 0.0 0.22 10.1 0.0 1.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1679) Kinase-like PF14531.1 KEG15076.1 - 0.095 11.6 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF771 PF05595.6 KEG15076.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF771) Kdo PF06293.9 KEG15076.1 - 0.15 11.0 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_S2 PF00318.15 KEG15077.1 - 0.14 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S2 DUF4359 PF14271.1 KEG15077.1 - 0.16 12.3 0.5 0.58 10.5 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4359) CoaE PF01121.15 KEG15078.1 - 5.5e-24 84.5 2.7 3.5e-23 81.9 1.9 2.1 1 1 0 1 1 1 1 Dephospho-CoA kinase NTF2 PF02136.15 KEG15079.1 - 1.2e-06 28.9 0.0 2.1e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_6 PF14259.1 KEG15079.1 - 5.2e-06 26.3 0.0 1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEG15079.1 - 0.00054 19.5 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF35_N PF12172.3 KEG15080.1 - 3.7 7.5 8.0 1.7 8.6 0.4 2.7 2 1 1 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF4379 PF14311.1 KEG15081.1 - 3.6e-21 74.7 6.7 2e-11 43.5 0.2 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF4379) SprT-like PF10263.4 KEG15081.1 - 0.053 13.1 4.9 0.44 10.1 0.2 2.5 2 1 0 2 2 2 0 SprT-like family DUF2296 PF10058.4 KEG15081.1 - 0.064 13.0 3.7 32 4.3 0.3 3.6 3 0 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) Elf1 PF05129.8 KEG15081.1 - 0.16 11.6 2.0 2.2 8.0 0.1 2.8 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like zf-C2H2_4 PF13894.1 KEG15081.1 - 0.54 10.7 7.9 26 5.4 0.2 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger DZR PF12773.2 KEG15081.1 - 4.2 7.2 8.2 9.4 6.1 1.8 2.7 2 1 0 2 2 2 0 Double zinc ribbon DnaJ PF00226.26 KEG15082.1 - 7.6e-17 60.8 0.1 1.3e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain FtsH_ext PF06480.10 KEG15082.1 - 0.016 15.3 0.1 14 5.9 0.1 2.8 2 1 1 3 3 3 0 FtsH Extracellular DUF4475 PF14753.1 KEG15083.1 - 3.1e-14 52.9 15.3 4.1e-12 46.0 0.7 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF4475) NOB1_Zn_bind PF08772.6 KEG15083.1 - 0.001 18.8 1.7 0.001 18.8 1.2 2.7 3 0 0 3 3 3 1 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_2 PF13240.1 KEG15083.1 - 0.04 13.4 0.6 0.04 13.4 0.4 3.6 3 1 0 3 3 3 0 zinc-ribbon domain ATP12 PF07542.6 KEG15084.1 - 1.7e-26 92.5 0.0 3.7e-26 91.4 0.0 1.6 1 0 0 1 1 1 1 ATP12 chaperone protein Mei5 PF10376.4 KEG15084.1 - 0.0021 17.6 1.5 0.003 17.1 1.0 1.2 1 0 0 1 1 1 1 Double-strand recombination repair protein Peptidase_C13 PF01650.13 KEG15085.1 - 9.8e-36 123.3 0.0 1.2e-35 123.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase C13 family TTL PF03133.10 KEG15086.1 - 2.4e-81 272.8 0.0 3.3e-81 272.4 0.0 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 KEG15086.1 - 1e-07 31.0 0.0 0.00016 20.5 0.0 2.3 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 KEG15086.1 - 0.0063 16.2 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain DUF3884 PF13024.1 KEG15086.1 - 0.012 15.0 0.0 0.031 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3884) ATPgrasp_ST PF14397.1 KEG15086.1 - 0.075 12.1 0.0 2.1 7.3 0.0 2.2 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Cas_Csy4 PF09618.5 KEG15086.1 - 0.094 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) DUF2036 PF09724.4 KEG15088.1 - 0.16 11.0 2.7 0.32 10.1 1.9 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2036) Nuc_sug_transp PF04142.10 KEG15089.1 - 9.9e-63 211.4 7.6 9.9e-63 211.4 5.2 1.7 2 0 0 2 2 2 1 Nucleotide-sugar transporter UAA PF08449.6 KEG15089.1 - 1.1e-08 34.3 8.9 1.6e-08 33.8 6.1 1.3 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 KEG15089.1 - 4.7e-08 33.1 22.4 6.5e-06 26.2 3.9 2.8 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 KEG15089.1 - 1.3e-05 25.3 5.6 1.3e-05 25.3 3.9 2.9 3 1 0 3 3 3 1 Multidrug resistance efflux transporter TPT PF03151.11 KEG15089.1 - 0.00025 20.7 9.6 0.00025 20.7 6.7 3.0 2 2 0 2 2 2 1 Triose-phosphate Transporter family PAP2 PF01569.16 KEG15092.1 - 1.2e-17 63.7 3.1 1.2e-17 63.7 2.2 2.1 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 KEG15092.1 - 0.00048 19.6 0.4 0.16 11.4 0.0 2.6 1 1 1 2 2 2 2 PAP2 superfamily CbiM PF01891.11 KEG15092.1 - 0.046 13.3 0.6 0.49 9.9 0.1 2.1 2 0 0 2 2 2 0 Cobalt uptake substrate-specific transmembrane region DUF2407_C PF13373.1 KEG15092.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 DUF2407 C-terminal domain Tic20 PF09685.5 KEG15092.1 - 0.13 12.2 4.2 0.18 11.7 0.4 2.3 2 0 0 2 2 2 0 Tic20-like protein ATP-synt_C PF00137.16 KEG15092.1 - 0.17 11.7 6.3 1.2 9.0 0.1 2.9 3 0 0 3 3 3 0 ATP synthase subunit C DUF2975 PF11188.3 KEG15092.1 - 0.27 10.9 4.0 0.63 9.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) Yip1 PF04893.12 KEG15092.1 - 0.41 10.1 7.1 37 3.7 4.9 2.3 1 1 0 1 1 1 0 Yip1 domain DUF3169 PF11368.3 KEG15092.1 - 0.7 9.0 3.8 6.7 5.8 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) PAP2 PF01569.16 KEG15093.1 - 9.7e-21 73.7 1.7 1.3e-20 73.3 1.1 1.1 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.1 KEG15093.1 - 0.081 12.4 0.4 0.28 10.6 0.3 1.9 1 1 0 1 1 1 0 PAP2 superfamily CAP_GLY PF01302.20 KEG15095.1 - 6e-25 86.7 0.3 1.1e-24 85.8 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 KEG15095.1 - 2.4e-23 82.1 0.1 4.1e-23 81.4 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 KEG15095.1 - 0.00055 19.2 0.2 0.011 15.1 0.1 2.3 1 1 0 1 1 1 1 Ubiquitin family WD40 PF00400.27 KEG15096.1 - 2.9e-60 198.1 21.5 1.7e-10 40.3 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KEG15096.1 - 0.00022 19.5 4.8 0.25 9.4 0.2 3.3 2 1 1 3 3 3 2 Nucleoporin Nup120/160 MbeD_MobD PF04899.7 KEG15096.1 - 0.021 14.6 2.4 0.1 12.5 0.6 2.6 2 1 1 3 3 3 0 MbeD/MobD like FlxA PF14282.1 KEG15096.1 - 0.023 14.6 13.3 0.045 13.6 3.4 2.3 1 1 0 2 2 2 0 FlxA-like protein DUF3312 PF11768.3 KEG15096.1 - 0.043 12.0 0.3 0.23 9.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) BLOC1_2 PF10046.4 KEG15096.1 - 0.098 12.7 2.7 0.25 11.5 1.9 1.7 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_13 PF13166.1 KEG15096.1 - 0.3 9.5 10.8 0.38 9.1 7.5 1.1 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 KEG15096.1 - 0.43 8.3 9.8 0.6 7.8 6.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Taxilin PF09728.4 KEG15096.1 - 0.94 8.5 20.8 1.5 7.8 13.0 1.9 1 1 1 2 2 2 0 Myosin-like coiled-coil protein CENP-F_leu_zip PF10473.4 KEG15096.1 - 1.2 9.0 19.1 1.1 9.1 2.9 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FUSC PF04632.7 KEG15096.1 - 2.4 6.4 5.7 3.3 6.0 3.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2939 PF11159.3 KEG15096.1 - 3.2 8.0 5.7 1 9.5 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) APG6 PF04111.7 KEG15096.1 - 6.7 5.6 15.6 10 5.0 10.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 UDG PF03167.14 KEG15097.1 - 1.3e-20 73.3 0.0 1.8e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily BTB_2 PF02214.17 KEG15098.1 - 2.8e-11 43.4 0.0 4.8e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Aconitase PF00330.15 KEG15100.1 - 2.2e-142 474.8 0.0 3e-142 474.3 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KEG15100.1 - 4.5e-42 143.2 0.0 9.3e-42 142.2 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF3505 PF12013.3 KEG15101.1 - 2 8.6 9.1 5.6 7.2 2.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3505) TBCC PF07986.7 KEG15102.1 - 1.1e-37 128.0 0.2 1.6e-37 127.5 0.1 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C FOP_dimer PF09398.5 KEG15102.1 - 1.3e-06 28.3 0.0 2.5e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 FOP N terminal dimerisation domain CAP_C PF08603.6 KEG15102.1 - 0.016 14.5 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal Nucleoplasmin PF03066.10 KEG15102.1 - 0.43 10.0 9.3 1.4 8.4 1.6 2.7 2 0 0 2 2 2 0 Nucleoplasmin DUF3340 PF11818.3 KEG15104.1 - 1.4 8.8 10.2 2.2 8.2 7.0 1.3 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) V-ATPase_C PF03223.10 KEG15105.1 - 4.7e-93 312.0 0.9 5.4e-93 311.8 0.6 1.0 1 0 0 1 1 1 1 V-ATPase subunit C PapD-like PF14874.1 KEG15106.1 - 6.7e-09 35.6 4.1 0.00083 19.2 0.1 5.2 5 0 0 5 5 5 3 Flagellar-associated PapD-like Motile_Sperm PF00635.21 KEG15106.1 - 1.2e-06 28.1 4.8 0.00038 20.0 0.1 5.2 5 1 0 5 5 5 1 MSP (Major sperm protein) domain SH3_3 PF08239.6 KEG15109.1 - 0.0054 16.8 0.0 5 7.4 0.0 2.9 2 1 0 2 2 2 2 Bacterial SH3 domain ABC_membrane_2 PF06472.10 KEG15110.1 - 8.5e-32 110.3 2.4 1.3e-31 109.7 1.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KEG15110.1 - 6.7e-17 62.0 0.0 1.9e-16 60.6 0.0 1.8 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 KEG15110.1 - 4e-07 29.4 0.1 1.2e-05 24.6 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 KEG15110.1 - 0.0016 18.3 0.0 0.0043 16.9 0.0 1.7 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 KEG15110.1 - 0.0019 18.2 0.0 0.009 16.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KEG15110.1 - 0.0046 16.6 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain DUF2813 PF11398.3 KEG15110.1 - 0.01 14.9 0.2 0.031 13.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) ABC_membrane PF00664.18 KEG15110.1 - 0.018 14.4 2.7 0.097 12.0 1.9 1.9 1 1 0 1 1 1 0 ABC transporter transmembrane region AAA_22 PF13401.1 KEG15110.1 - 0.019 15.0 0.1 0.2 11.8 0.0 2.5 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KEG15110.1 - 0.035 14.4 0.0 0.069 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KEG15110.1 - 0.1 12.2 0.0 0.49 10.0 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase DUF3198 PF11433.3 KEG15110.1 - 0.16 11.8 0.1 2.4 8.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3198) AAA_15 PF13175.1 KEG15110.1 - 0.25 10.3 0.0 0.46 9.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Vasohibin PF14822.1 KEG15111.1 - 1.9e-56 190.9 0.0 3.8e-56 189.9 0.0 1.4 1 0 0 1 1 1 1 Vasohibin Brix PF04427.13 KEG15112.1 - 3.7e-44 150.6 0.2 6.6e-44 149.8 0.2 1.4 1 0 0 1 1 1 1 Brix domain RNA_pol_Rpb2_45 PF10385.4 KEG15114.1 - 0.071 12.9 0.4 0.33 10.7 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase beta subunit external 1 domain PfkB PF00294.19 KEG15115.1 - 3.3e-63 213.6 0.3 3.8e-63 213.4 0.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 KEG15115.1 - 3.8e-11 42.6 0.0 6.1e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DnaJ PF00226.26 KEG15116.1 - 1.3e-24 85.7 0.8 2.1e-24 85.0 0.6 1.4 1 0 0 1 1 1 1 DnaJ domain Apolipoprotein PF01442.13 KEG15117.1 - 0.011 15.2 11.8 0.024 14.1 8.2 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Img2 PF05046.9 KEG15117.1 - 0.082 13.1 0.4 0.15 12.3 0.2 1.7 1 1 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) APG9 PF04109.11 KEG15118.1 - 1.4e-51 175.5 0.4 1.4e-51 175.5 0.3 1.8 2 0 0 2 2 2 1 Autophagy protein Apg9 Nup96 PF12110.3 KEG15119.1 - 8e-32 110.4 0.0 1.4e-31 109.7 0.0 1.3 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 KEG15119.1 - 3.3e-22 78.8 0.0 1.1e-21 77.1 0.0 1.9 1 1 0 1 1 1 1 Nucleoporin autopeptidase AAA PF00004.24 KEG15122.1 - 3.9e-37 127.3 0.0 1e-35 122.8 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEG15122.1 - 3.5e-05 23.8 1.8 0.0008 19.4 0.1 3.1 3 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 KEG15122.1 - 0.0024 17.5 0.0 0.012 15.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KEG15122.1 - 0.0052 17.5 0.0 0.013 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 KEG15122.1 - 0.0071 15.0 0.0 0.029 13.0 0.0 1.8 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 KEG15122.1 - 0.01 15.7 0.0 0.036 13.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KEG15122.1 - 0.11 12.3 0.0 0.62 9.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KEG15122.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF815 PF05673.8 KEG15122.1 - 0.16 10.8 0.0 0.38 9.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 KEG15122.1 - 0.18 11.4 0.0 7.7 6.1 0.0 2.4 1 1 1 2 2 2 0 Archaeal ATPase RRM_1 PF00076.17 KEG15123.1 - 2.6e-12 46.1 0.0 1.1e-06 28.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG15123.1 - 1.2e-11 44.4 0.0 6.9e-10 38.7 0.0 2.9 3 1 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG15123.1 - 8.4e-09 35.1 0.2 2.6e-08 33.5 0.1 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribonuclease_3 PF00636.21 KEG15124.1 - 0.04 14.3 0.0 0.063 13.7 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease III domain DUF3377 PF11857.3 KEG15125.1 - 0.002 17.7 0.5 0.0069 15.9 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3377) DUF1180 PF06679.7 KEG15125.1 - 0.0028 17.5 3.7 0.028 14.2 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1180) Herpes_gE PF02480.11 KEG15125.1 - 0.0045 15.3 0.1 0.0065 14.7 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 KEG15125.1 - 0.0062 16.8 1.2 0.015 15.6 0.8 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SP_C-Propep PF08999.5 KEG15125.1 - 0.0064 15.9 3.3 0.016 14.6 2.3 1.7 1 0 0 1 1 1 1 Surfactant protein C, N terminal propeptide Shisa PF13908.1 KEG15125.1 - 0.0065 16.6 0.5 0.0065 16.6 0.3 1.9 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator DUF3609 PF12259.3 KEG15125.1 - 0.0077 14.9 0.1 0.01 14.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3609) AJAP1_PANP_C PF15298.1 KEG15125.1 - 0.0085 16.0 3.1 0.48 10.2 0.0 2.1 2 0 0 2 2 2 1 AJAP1/PANP C-terminus LRR19-TM PF15176.1 KEG15125.1 - 0.015 14.9 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DUF912 PF06024.7 KEG15125.1 - 0.02 14.9 0.1 0.036 14.0 0.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DAG1 PF05454.6 KEG15125.1 - 0.02 14.0 2.1 0.021 14.0 0.5 1.7 1 1 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Ly49 PF08391.5 KEG15125.1 - 0.02 14.9 0.0 0.033 14.3 0.0 1.3 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region NPDC1 PF06809.6 KEG15125.1 - 0.038 12.8 1.6 0.77 8.4 0.0 2.1 2 0 0 2 2 2 0 Neural proliferation differentiation control-1 protein (NPDC1) Neur_chan_memb PF02932.11 KEG15125.1 - 0.041 13.7 2.5 0.082 12.7 1.7 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4448 PF14610.1 KEG15125.1 - 0.051 13.0 0.7 0.096 12.1 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF4366 PF14283.1 KEG15125.1 - 0.13 11.6 0.2 0.52 9.7 0.0 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4366) DUF2644 PF10841.3 KEG15125.1 - 0.19 11.7 1.3 0.37 10.8 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2644) Baculo_11_kDa PF06143.6 KEG15125.1 - 0.24 10.7 6.9 0.05 12.9 2.3 1.7 2 0 0 2 2 2 0 Baculovirus 11 kDa family TMEM154 PF15102.1 KEG15125.1 - 2.9 7.5 7.0 0.67 9.6 0.0 2.2 2 0 0 2 2 2 0 TMEM154 protein family FliJ PF02050.11 KEG15126.1 - 0.01 15.8 10.1 0.021 14.8 5.8 2.4 1 1 0 1 1 1 0 Flagellar FliJ protein Herpes_UL33 PF03581.8 KEG15126.1 - 0.033 14.0 0.5 0.2 11.5 0.1 2.4 2 0 0 2 2 2 0 Herpesvirus UL33-like protein AKNA PF12443.3 KEG15126.1 - 0.22 11.5 3.9 0.19 11.7 0.6 2.5 2 1 0 2 2 2 0 AT-hook-containing transcription factor TIP120 PF08623.5 KEG15128.1 - 1.7e-12 47.2 0.1 1e-10 41.4 0.0 3.6 2 1 0 2 2 2 1 TATA-binding protein interacting (TIP20) Iso_dh PF00180.15 KEG15129.1 - 3.8e-76 256.2 0.0 4.4e-76 256.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase TPR_12 PF13424.1 KEG15130.1 - 2.5e-22 78.5 34.6 0.00031 20.5 0.5 9.9 9 1 1 10 10 10 6 Tetratricopeptide repeat TPR_14 PF13428.1 KEG15130.1 - 4.8e-11 42.2 34.5 0.00067 20.0 0.5 12.8 11 5 5 16 16 13 4 Tetratricopeptide repeat TPR_11 PF13414.1 KEG15130.1 - 1.9e-09 36.9 32.2 5.1e-06 26.0 0.2 8.8 9 1 0 9 9 9 3 TPR repeat TPR_7 PF13176.1 KEG15130.1 - 5e-09 35.2 18.2 0.28 11.0 0.0 9.5 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 KEG15130.1 - 5.5e-08 33.0 25.9 0.00022 21.4 1.8 8.8 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEG15130.1 - 1.2e-05 25.8 39.1 0.019 15.6 0.4 11.0 8 3 4 12 12 12 3 Tetratricopeptide repeat TPR_17 PF13431.1 KEG15130.1 - 0.00021 21.2 1.6 0.82 10.0 0.0 4.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 KEG15130.1 - 0.0044 17.4 15.5 8.4 7.1 0.0 9.2 10 1 1 11 11 10 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEG15130.1 - 0.005 16.5 2.8 3.3 7.6 0.0 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEG15130.1 - 0.014 15.2 35.4 2.3 8.3 0.0 11.8 14 0 0 14 14 13 0 Tetratricopeptide repeat TPR_10 PF13374.1 KEG15130.1 - 0.019 14.8 21.2 7.3 6.6 0.2 8.5 8 0 0 8 8 8 0 Tetratricopeptide repeat Pro_isomerase PF00160.16 KEG15131.1 - 2.3e-44 151.3 0.4 2.6e-44 151.1 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WW PF00397.21 KEG15132.1 - 2.2e-05 24.2 0.1 4.8e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 WW domain Ribosomal_L23 PF00276.15 KEG15133.1 - 1.3e-05 25.0 0.7 2.1e-05 24.3 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L23 LRR_8 PF13855.1 KEG15134.1 - 2.9e-17 62.1 12.2 7.8e-15 54.3 0.9 3.6 2 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.2 KEG15134.1 - 7.9e-13 47.7 10.4 7.3e-06 25.4 0.4 3.7 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEG15134.1 - 1.5e-05 24.3 10.7 0.35 11.0 0.2 5.8 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.1 KEG15134.1 - 0.00016 21.3 3.2 27 5.2 0.1 5.2 5 0 0 5 5 5 0 Leucine Rich repeat LRR_9 PF14580.1 KEG15134.1 - 0.0025 17.4 0.1 0.0069 15.9 0.0 1.7 1 0 0 1 1 1 1 Leucine-rich repeat LRR_7 PF13504.1 KEG15134.1 - 0.0084 16.1 6.6 6.3 7.4 0.1 5.3 4 1 0 4 4 4 1 Leucine rich repeat Kdo PF06293.9 KEG15135.1 - 3.6e-09 35.9 0.2 5.8e-09 35.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KEG15135.1 - 9.5e-09 34.8 0.0 1.5e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.20 KEG15135.1 - 2.4e-07 30.1 0.0 2.9e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KEG15135.1 - 0.00025 20.8 1.9 0.0036 17.0 0.2 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KEG15135.1 - 0.021 13.8 0.2 0.031 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase DUF1702 PF08012.6 KEG15135.1 - 0.069 11.7 0.0 2 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1702) Phytochelatin PF05023.9 KEG15136.1 - 2.5e-07 29.8 0.0 0.042 12.8 0.0 4.1 4 0 0 4 4 4 4 Phytochelatin synthase Acetyltransf_1 PF00583.19 KEG15137.1 - 3.4e-07 30.1 0.1 0.00049 20.0 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEG15137.1 - 0.0001 22.3 0.0 0.003 17.6 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Mito_carr PF00153.22 KEG15138.1 - 4.6e-29 99.9 3.7 3.7e-12 45.7 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein MCRS_N PF13325.1 KEG15139.1 - 8.4e-05 22.1 0.0 0.00017 21.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal region of micro-spherule protein Myb_DNA-bind_6 PF13921.1 KEG15139.1 - 0.00011 22.2 0.0 0.00025 21.0 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KEG15139.1 - 0.0038 17.2 0.0 0.0086 16.1 0.0 1.7 1 1 0 1 1 1 1 Myb-like DNA-binding domain PIH1 PF08190.7 KEG15140.1 - 1.9e-30 106.4 7.9 2.1e-28 99.7 0.0 4.6 2 2 0 2 2 2 1 pre-RNA processing PIH1/Nop17 Beta_helix PF13229.1 KEG15141.1 - 0.00049 19.8 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 Right handed beta helix region SET PF00856.23 KEG15142.1 - 8.7e-07 29.3 0.0 4.3e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 SET domain tRNA-synt_2c PF01411.14 KEG15142.1 - 0.19 9.9 0.0 0.27 9.4 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class II (A) UQ_con PF00179.21 KEG15143.1 - 0.00016 21.0 0.0 0.00049 19.5 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme ProRS-C_1 PF09180.6 KEG15144.1 - 8.4e-26 89.6 3.6 8.6e-26 89.6 0.9 2.3 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal tRNA_edit PF04073.10 KEG15144.1 - 1.9e-25 89.0 0.1 3.4e-25 88.2 0.1 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain tRNA-synt_2b PF00587.20 KEG15144.1 - 7e-18 64.8 0.0 1.4e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KEG15144.1 - 4e-15 55.5 0.0 1.3e-14 53.9 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain Complex1_LYR PF05347.10 KEG15145.1 - 5.7e-12 45.2 1.1 5.7e-12 45.2 0.8 1.7 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KEG15145.1 - 2.9e-11 43.3 1.5 5.7e-11 42.4 1.0 1.5 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 KEG15145.1 - 0.072 13.5 0.2 0.14 12.6 0.2 1.5 1 0 0 1 1 1 0 Complex1_LYR-like Cmc1 PF08583.5 KEG15148.1 - 0.0011 18.7 0.8 0.0019 17.9 0.6 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 KEG15148.1 - 0.3 11.0 3.0 2 8.4 0.1 2.6 2 0 0 2 2 2 0 CHCH domain zf-C3HC4_3 PF13920.1 KEG15150.1 - 3.8e-15 55.2 11.9 6.4e-15 54.5 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEG15150.1 - 4.5e-08 32.9 14.7 7.9e-08 32.2 10.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEG15150.1 - 3.1e-05 23.6 13.2 5.6e-05 22.8 9.1 1.4 1 0 0 1 1 1 1 Ring finger domain SprA-related PF12118.3 KEG15150.1 - 0.0075 15.6 19.7 0.015 14.6 13.7 1.4 1 0 0 1 1 1 1 SprA-related family zf-RING_5 PF14634.1 KEG15150.1 - 0.025 14.2 11.9 0.051 13.3 8.2 1.5 1 0 0 1 1 1 0 zinc-RING finger domain FCP1_C PF09309.5 KEG15150.1 - 0.042 13.1 8.5 0.068 12.4 5.9 1.4 1 0 0 1 1 1 0 FCP1, C-terminal Suf PF05843.9 KEG15150.1 - 0.043 13.5 13.8 0.072 12.8 9.6 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4557 PF15101.1 KEG15150.1 - 0.047 13.5 7.1 0.089 12.6 5.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) TFIIA PF03153.8 KEG15150.1 - 0.37 10.6 20.7 0.46 10.3 14.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-P11 PF03854.9 KEG15150.1 - 0.59 9.6 9.0 1.4 8.4 6.2 1.7 1 1 0 1 1 1 0 P-11 zinc finger RR_TM4-6 PF06459.7 KEG15150.1 - 1.1 9.1 9.6 2.2 8.0 6.7 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_pol_Rpc4 PF05132.9 KEG15150.1 - 1.2 9.1 11.9 2.8 7.9 8.3 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF4407 PF14362.1 KEG15150.1 - 4.5 6.1 7.4 7.8 5.3 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Activator_LAG-3 PF11498.3 KEG15150.1 - 4.6 5.8 34.8 6.7 5.3 24.1 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Ndc1_Nup PF09531.5 KEG15150.1 - 5 5.4 9.0 6 5.1 6.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF605 PF04652.11 KEG15150.1 - 6.7 5.9 23.7 11 5.2 16.5 1.3 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 KEG15150.1 - 9.5 4.3 34.2 14 3.7 23.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ATG16 PF08614.6 KEG15151.1 - 0.00042 20.2 13.4 0.00042 20.2 9.3 8.7 1 1 6 7 7 7 1 Autophagy protein 16 (ATG16) Ras PF00071.17 KEG15152.1 - 3e-53 179.5 0.0 3.5e-53 179.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEG15152.1 - 2.5e-12 47.3 0.0 4.5e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEG15152.1 - 8.4e-10 38.1 0.0 1.4e-09 37.4 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KEG15152.1 - 0.00013 21.2 0.0 0.00018 20.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KEG15152.1 - 0.012 15.6 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.1 KEG15152.1 - 0.1 12.7 0.0 0.27 11.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 KEG15152.1 - 0.14 11.3 0.0 0.42 9.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 zf-AN1 PF01428.11 KEG15153.1 - 1.3e-18 66.5 23.5 6.5e-10 38.7 3.5 3.2 2 1 1 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.10 KEG15153.1 - 0.0014 18.7 19.3 0.025 14.7 1.1 2.8 3 0 0 3 3 3 2 Tc5 transposase C-terminal domain Nol1_Nop2_Fmu PF01189.12 KEG15154.1 - 6.9e-26 91.2 0.0 6.6e-25 88.0 0.0 2.4 2 1 0 2 2 2 1 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 KEG15154.1 - 0.0011 18.9 0.0 0.0037 17.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KEG15154.1 - 0.052 13.5 0.0 0.093 12.7 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase POR PF01558.13 KEG15154.1 - 0.17 11.8 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Ank_2 PF12796.2 KEG15155.1 - 7.9e-27 93.4 0.4 3e-12 46.7 0.0 3.5 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KEG15155.1 - 7.1e-26 88.6 0.5 5.5e-07 29.0 0.1 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 KEG15155.1 - 1.2e-21 76.6 0.4 2.7e-05 24.5 0.0 5.1 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEG15155.1 - 1.2e-21 74.5 0.7 3.6e-05 23.5 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 KEG15155.1 - 9.1e-21 73.4 2.8 4.8e-10 39.3 0.0 4.9 2 2 3 5 5 5 4 Ankyrin repeats (many copies) PDEase_I PF00233.14 KEG15156.1 - 1.9e-67 227.4 0.4 3.6e-67 226.5 0.3 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DUF4391 PF14335.1 KEG15156.1 - 0.56 9.5 9.3 2.8 7.2 2.6 2.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4391) Pkinase PF00069.20 KEG15157.1 - 1.6e-71 240.5 0.0 1.8e-71 240.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG15157.1 - 1.6e-36 125.7 0.0 2e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG15157.1 - 2e-05 23.7 0.0 2.6e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Vps16_N PF04841.8 KEG15158.1 - 6.5e-41 140.2 0.0 1.5e-40 139.0 0.0 1.6 1 1 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 KEG15158.1 - 1.9e-33 115.7 1.3 5.9e-31 107.5 0.9 2.3 1 1 0 1 1 1 1 Vps16, C-terminal region Frigida PF07899.6 KEG15158.1 - 0.017 13.8 0.0 0.51 9.0 0.0 2.3 1 1 1 2 2 2 0 Frigida-like protein Herpes_capsid PF06112.6 KEG15158.1 - 0.048 13.6 0.5 1.6 8.7 0.1 2.3 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Peptidase_C2 PF00648.16 KEG15159.1 - 1.3e-18 67.0 0.0 2.3e-17 62.9 0.0 2.2 2 0 0 2 2 2 1 Calpain family cysteine protease Calpain_III PF01067.17 KEG15159.1 - 0.00013 21.6 0.1 0.0019 17.8 0.0 2.2 2 0 0 2 2 2 1 Calpain large subunit, domain III CobN-Mg_chel PF02514.11 KEG15160.1 - 0.0006 17.3 9.2 0.00077 17.0 6.4 1.1 1 0 0 1 1 1 1 CobN/Magnesium Chelatase DUF641 PF04859.7 KEG15160.1 - 0.024 14.4 0.7 0.024 14.4 0.5 3.6 2 1 2 4 4 4 0 Plant protein of unknown function (DUF641) Baculo_PEP_C PF04513.7 KEG15160.1 - 0.12 12.1 3.8 0.31 10.8 0.7 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ZYG-11_interact PF05884.7 KEG15160.1 - 0.28 10.2 0.5 0.49 9.4 0.4 1.4 1 0 0 1 1 1 0 Interactor of ZYG-11 Prominin PF05478.6 KEG15160.1 - 0.66 7.4 4.6 0.69 7.3 2.7 1.4 1 1 0 1 1 1 0 Prominin KapB PF08810.5 KEG15160.1 - 0.89 9.6 6.9 8.4 6.4 0.7 2.9 1 1 2 3 3 3 0 Kinase associated protein B Fib_alpha PF08702.5 KEG15160.1 - 1.6 8.8 16.6 4.7 7.3 6.2 2.6 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3584 PF12128.3 KEG15160.1 - 2.8 5.1 27.3 1.8 5.7 17.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Spore_III_AF PF09581.5 KEG15160.1 - 6.7 6.5 9.6 0.31 10.8 0.4 2.6 1 1 1 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) WD40 PF00400.27 KEG15162.1 - 5.2e-23 80.0 10.9 4.5e-05 23.1 0.0 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat DUF3312 PF11768.3 KEG15162.1 - 0.21 9.7 0.0 0.34 9.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) PPR_2 PF13041.1 KEG15163.1 - 2e-07 30.8 0.0 0.021 14.7 0.0 3.4 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.1 KEG15163.1 - 2.4e-06 27.3 10.1 1.3 9.4 0.0 7.3 8 0 0 8 8 8 3 Pentatricopeptide repeat domain PPR PF01535.15 KEG15163.1 - 0.00042 20.1 0.0 11 6.2 0.0 4.9 5 0 0 5 5 5 2 PPR repeat Laminin_I PF06008.9 KEG15163.1 - 0.2 10.9 4.8 2.9 7.1 3.3 2.2 1 1 0 1 1 1 0 Laminin Domain I Glyco_trans_1_4 PF13692.1 KEG15164.1 - 2e-09 37.7 0.0 4.9e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pro_isomerase PF00160.16 KEG15165.1 - 1.9e-38 132.0 0.1 4.9e-38 130.7 0.0 1.7 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Tox-WTIP PF15654.1 KEG15166.1 - 0.058 13.0 0.4 0.12 11.9 0.2 1.6 1 0 0 1 1 1 0 Toxin with a conserved tryptophan and TIP tripeptide motif Miro PF08477.8 KEG15168.1 - 0.0041 17.5 0.0 0.022 15.2 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 KEG15168.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Ras PF00071.17 KEG15168.1 - 0.21 10.9 0.0 2 7.7 0.0 2.3 2 0 0 2 2 2 0 Ras family Metallophos PF00149.23 KEG15169.1 - 2.7e-13 49.7 1.4 4.4e-13 49.0 1.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KEG15169.1 - 1.5e-06 28.1 0.1 3.2e-06 27.0 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain 14-3-3 PF00244.15 KEG15171.1 - 1.8e-05 23.9 0.7 0.13 11.2 0.0 2.9 3 0 0 3 3 3 2 14-3-3 protein DUF1314 PF07013.6 KEG15171.1 - 0.028 13.8 0.1 0.092 12.1 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1314) RNA12 PF10443.4 KEG15171.1 - 0.066 11.6 0.2 0.1 11.0 0.2 1.2 1 0 0 1 1 1 0 RNA12 protein WD40 PF00400.27 KEG15172.1 - 1.9e-33 113.0 16.9 1.3e-08 34.3 0.1 12.5 13 0 0 13 13 13 6 WD domain, G-beta repeat Utp12 PF04003.7 KEG15172.1 - 2.6e-07 30.5 0.0 4.4e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family PD40 PF07676.7 KEG15172.1 - 0.37 10.5 1.4 32 4.3 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 KEG15172.1 - 5.6 6.3 7.3 2.7 7.4 0.0 3.9 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Cnd1 PF12717.2 KEG15173.1 - 2.2e-05 24.4 0.8 0.0071 16.2 0.0 4.8 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 KEG15173.1 - 0.00022 21.5 1.9 0.41 11.0 0.0 5.5 5 1 0 6 6 6 1 Vacuolar 14 Fab1-binding region TIP120 PF08623.5 KEG15173.1 - 0.0059 16.1 6.2 1.7 8.2 0.0 5.5 5 0 0 5 5 5 1 TATA-binding protein interacting (TIP20) HEAT_EZ PF13513.1 KEG15173.1 - 0.079 13.4 18.0 0.58 10.7 0.0 8.4 7 1 2 9 9 9 0 HEAT-like repeat ATP-cone PF03477.11 KEG15173.1 - 0.38 11.2 4.6 0.53 10.7 0.1 3.7 3 0 0 3 3 3 0 ATP cone domain CDP-OH_P_transf PF01066.16 KEG15174.1 - 5.4e-21 74.7 2.5 5.4e-21 74.7 1.7 3.5 2 1 2 4 4 4 1 CDP-alcohol phosphatidyltransferase Ribosomal_S8 PF00410.14 KEG15175.1 - 1.3e-11 44.4 0.0 1.7e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 RNA_pol_Rpb5_C PF01191.14 KEG15176.1 - 2.6e-24 84.6 0.0 4.6e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 KEG15176.1 - 8.3e-05 22.9 0.0 0.0044 17.4 0.0 2.3 1 1 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain RNA_pol_Rpb5_C PF01191.14 KEG15177.1 - 4.6e-29 99.8 0.1 7.3e-29 99.1 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 KEG15177.1 - 3.4e-22 78.6 0.9 3.4e-22 78.6 0.6 1.8 2 1 0 2 2 2 1 RNA polymerase Rpb5, N-terminal domain LysM PF01476.15 KEG15178.1 - 0.011 15.5 0.0 0.1 12.5 0.0 2.2 2 0 0 2 2 2 0 LysM domain PDZ_2 PF13180.1 KEG15178.1 - 0.016 15.0 0.0 0.043 13.7 0.0 1.7 1 0 0 1 1 1 0 PDZ domain zf-C2H2_jaz PF12171.3 KEG15179.1 - 0.00045 20.2 2.6 0.00062 19.8 1.8 1.2 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KEG15179.1 - 0.0059 16.7 2.7 0.0087 16.2 1.8 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.7 KEG15179.1 - 0.008 15.7 1.0 0.012 15.1 0.7 1.2 1 0 0 1 1 1 1 U1 zinc finger DUF2051 PF09738.4 KEG15180.1 - 0.0026 17.1 2.4 0.01 15.1 0.2 2.4 2 0 0 2 2 2 1 Double stranded RNA binding protein (DUF2051) MIF4G_like_2 PF09090.6 KEG15180.1 - 0.14 11.3 1.1 0.33 10.1 0.8 1.5 1 0 0 1 1 1 0 MIF4G like LIM_bind PF01803.11 KEG15180.1 - 0.36 9.8 2.2 0.35 9.9 0.1 2.0 2 0 0 2 2 2 0 LIM-domain binding protein Phage_GPO PF05929.6 KEG15180.1 - 1.1 8.4 7.8 0.35 10.0 0.1 2.4 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase TFIIA PF03153.8 KEG15180.1 - 1.9 8.3 8.6 0.092 12.6 0.7 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-CCHC_2 PF13696.1 KEG15181.1 - 1.6e-06 27.4 5.4 1.6e-06 27.4 3.8 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.1 KEG15181.1 - 0.073 12.8 0.3 0.17 11.6 0.2 1.6 1 0 0 1 1 1 0 Zinc knuckle Zn-ribbon_8 PF09723.5 KEG15181.1 - 0.085 12.8 4.8 0.37 10.7 0.4 2.6 2 0 0 2 2 2 0 Zinc ribbon domain DWNN PF08783.6 KEG15181.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 DWNN domain zf-CCHC PF00098.18 KEG15181.1 - 0.17 11.8 7.9 0.047 13.6 3.0 2.0 2 0 0 2 2 2 0 Zinc knuckle NDUFA12 PF05071.11 KEG15182.1 - 7.8e-06 26.3 1.6 1.6e-05 25.3 0.5 1.9 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 ICMT PF04140.9 KEG15183.1 - 5.8e-21 74.4 1.7 5.8e-21 74.4 1.2 1.7 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 KEG15183.1 - 1e-06 28.7 1.4 1e-06 28.7 0.9 2.5 2 1 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 KEG15183.1 - 0.01 15.1 0.2 0.018 14.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) DUF165 PF02592.10 KEG15183.1 - 1.8 8.7 7.5 0.48 10.5 2.8 1.9 2 0 0 2 2 2 0 Uncharacterized ACR, YhhQ family COG1738 PAF-AH_p_II PF03403.8 KEG15184.1 - 3e-13 48.8 0.0 1.4e-11 43.3 0.0 2.0 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 KEG15184.1 - 2.2e-05 24.2 0.3 3.5e-05 23.5 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEG15184.1 - 0.0012 18.8 2.2 0.0023 17.8 1.3 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KEG15184.1 - 0.041 13.7 0.8 0.18 11.6 0.1 2.1 2 0 0 2 2 2 0 Putative lysophospholipase Abhydrolase_1 PF00561.15 KEG15184.1 - 0.16 11.4 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PAF-AH_p_II PF03403.8 KEG15185.1 - 2.8e-26 91.6 0.0 5.8e-26 90.6 0.0 1.5 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.2 KEG15185.1 - 1.2e-08 34.2 0.0 2.1e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_5 PF12695.2 KEG15185.1 - 2.4e-08 33.8 0.0 4e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEG15185.1 - 1.5e-05 25.0 0.4 2.6e-05 24.2 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 KEG15185.1 - 0.00023 20.0 0.0 0.016 14.0 0.0 2.2 2 0 0 2 2 2 1 Chlorophyllase Abhydrolase_1 PF00561.15 KEG15185.1 - 0.0016 18.0 0.0 0.0024 17.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 KEG15185.1 - 0.029 13.9 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S9 PF00326.16 KEG15185.1 - 0.11 11.7 0.0 0.31 10.2 0.0 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family Glyoxalase_2 PF12681.2 KEG15186.1 - 3.8e-16 59.6 0.0 4.7e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KEG15186.1 - 8e-15 54.9 0.1 1.1e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 KEG15186.1 - 2.7e-11 43.4 0.0 4.3e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.1 KEG15186.1 - 0.025 14.2 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 CppA N-terminal DNA_pol_A_exo1 PF01612.15 KEG15188.1 - 5e-14 52.1 0.0 7.7e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease zf-CCHC PF00098.18 KEG15188.1 - 1.2e-05 24.9 34.8 0.0028 17.5 2.0 4.6 4 1 0 4 4 4 3 Zinc knuckle zf-C4_ClpX PF06689.8 KEG15188.1 - 2.2 7.8 7.3 2 8.0 2.1 2.7 2 0 0 2 2 2 0 ClpX C4-type zinc finger CTDII PF01556.13 KEG15189.1 - 1.3e-23 82.6 0.1 1.3e-18 66.6 0.1 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 KEG15189.1 - 2.5e-21 75.1 0.4 5.1e-21 74.1 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KEG15189.1 - 5.2e-15 55.2 18.2 9.7e-15 54.3 12.6 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 KEG15189.1 - 0.018 14.7 6.6 0.059 13.0 0.4 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family VP_N-CPKC PF11475.3 KEG15189.1 - 0.28 10.7 1.2 1.8 8.1 0.1 2.5 2 0 0 2 2 2 0 Virion protein N terminal domain Galactosyl_T PF01762.16 KEG15190.1 - 1.2e-05 24.9 0.1 0.00046 19.8 0.1 2.8 3 1 0 3 3 3 1 Galactosyltransferase Zeta_toxin PF06414.7 KEG15191.1 - 5.6e-07 28.8 0.0 0.019 14.0 0.0 2.1 2 0 0 2 2 2 2 Zeta toxin AAA_17 PF13207.1 KEG15191.1 - 0.00024 21.8 0.0 0.00054 20.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KEG15191.1 - 0.0061 16.8 0.0 0.016 15.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 KEG15191.1 - 0.026 14.0 0.2 0.061 12.8 0.1 1.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.1 KEG15191.1 - 0.058 13.3 0.5 0.77 9.7 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KEG15191.1 - 0.082 12.7 0.0 0.2 11.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.15 KEG15191.1 - 0.097 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase TPR_11 PF13414.1 KEG15192.1 - 0.00056 19.5 0.1 0.018 14.6 0.1 2.3 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 KEG15192.1 - 0.0026 17.5 0.1 2.2 8.4 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat SOG2 PF10428.4 KEG15192.1 - 0.0043 15.7 0.3 0.0054 15.4 0.2 1.2 1 0 0 1 1 1 1 RAM signalling pathway protein TPR_1 PF00515.23 KEG15192.1 - 0.033 13.8 0.1 1.9 8.1 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 KEG15192.1 - 0.071 13.0 0.3 0.89 9.5 0.1 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat DENN PF02141.16 KEG15193.1 - 5.6e-24 84.8 1.0 8.6e-24 84.2 0.7 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 KEG15193.1 - 0.00014 21.7 0.1 0.00014 21.7 0.0 1.8 2 0 0 2 2 2 1 uDENN domain SPA PF08616.5 KEG15193.1 - 0.0011 18.6 0.2 0.0021 17.7 0.1 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis PPR PF01535.15 KEG15194.1 - 2.2e-25 86.8 32.6 0.0079 16.1 0.1 14.3 16 0 0 16 16 16 7 PPR repeat PPR_2 PF13041.1 KEG15194.1 - 1.3e-24 85.9 28.5 2.9e-05 23.9 0.0 12.8 7 3 7 14 14 14 8 PPR repeat family PPR_3 PF13812.1 KEG15194.1 - 1.2e-16 59.4 30.1 0.022 15.0 0.1 15.2 18 0 0 18 18 18 4 Pentatricopeptide repeat domain PPR_1 PF12854.2 KEG15194.1 - 3.9e-09 35.8 0.6 0.014 14.8 0.0 5.7 5 0 0 5 5 5 2 PPR repeat TPR_19 PF14559.1 KEG15194.1 - 0.00012 22.3 2.3 0.0081 16.4 1.6 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Cupin_8 PF13621.1 KEG15195.1 - 4.1e-47 160.8 0.0 6.2e-47 160.2 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.9 KEG15195.1 - 4.6e-27 94.7 0.2 8.3e-27 93.9 0.1 1.5 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_3 PF13415.1 KEG15195.1 - 7.4e-13 48.2 5.2 0.012 15.7 0.1 4.9 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.1 KEG15195.1 - 1.4e-09 37.6 0.1 0.00018 21.3 0.0 5.1 5 0 0 5 5 5 2 Kelch motif Cupin_4 PF08007.7 KEG15195.1 - 3.1e-08 33.2 0.0 7.7e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 Cupin superfamily protein Kelch_4 PF13418.1 KEG15195.1 - 4.4e-07 29.5 12.2 0.00069 19.3 0.2 5.9 4 1 1 5 5 5 1 Galactose oxidase, central domain Kelch_6 PF13964.1 KEG15195.1 - 0.00099 19.1 1.2 29 5.0 0.0 5.7 5 1 1 6 6 6 0 Kelch motif MTS PF05175.9 KEG15195.1 - 0.07 12.5 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain JmjC PF02373.17 KEG15195.1 - 0.078 13.2 0.1 0.22 11.7 0.1 1.8 1 0 0 1 1 1 0 JmjC domain, hydroxylase PSII_Pbs27 PF13326.1 KEG15195.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Photosystem II Pbs27 SIR2_2 PF13289.1 KEG15195.1 - 0.22 11.4 0.0 0.47 10.3 0.0 1.5 1 0 0 1 1 1 0 SIR2-like domain DUF342 PF03961.8 KEG15197.1 - 0.26 9.6 2.2 0.46 8.8 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF904 PF06005.7 KEG15197.1 - 1.5 9.2 14.2 11 6.4 0.5 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF904) PARG_cat PF05028.9 KEG15198.1 - 1.8e-104 349.6 0.0 2.4e-104 349.2 0.0 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) AKAP_110 PF05716.8 KEG15198.1 - 0.037 12.0 0.0 0.062 11.2 0.0 1.3 1 0 0 1 1 1 0 A-kinase anchor protein 110 kDa (AKAP 110) Tctex-1 PF03645.8 KEG15199.1 - 8.7e-26 89.7 0.0 1.1e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family SpoU_methylase PF00588.14 KEG15201.1 - 8.9e-09 35.3 0.0 2.1e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 SpoU rRNA Methylase family DUF972 PF06156.8 KEG15201.1 - 0.24 11.7 0.1 0.24 11.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Sybindin PF04099.7 KEG15202.1 - 2.2e-18 66.3 0.0 2.5e-18 66.1 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family CHU_C PF13585.1 KEG15202.1 - 0.13 12.1 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 C-terminal domain of CHU protein family Pkinase PF00069.20 KEG15203.1 - 3.3e-44 150.9 0.0 5.1e-44 150.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG15203.1 - 1.1e-26 93.5 0.0 5.7e-18 64.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KEG15203.1 - 0.00011 21.2 0.0 0.00021 20.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KEG15203.1 - 0.052 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 RIO1 family RHD PF00554.17 KEG15204.1 - 2.6 7.7 9.3 0.11 12.1 1.7 1.9 1 1 1 2 2 2 0 Rel homology domain (RHD) Leo1 PF04004.8 KEG15205.1 - 2.1e-25 89.4 0.1 2.1e-25 89.4 0.1 2.1 3 0 0 3 3 3 1 Leo1-like protein Cwf_Cwc_15 PF04889.7 KEG15205.1 - 0.044 13.4 15.3 0.072 12.7 10.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nucleo_P87 PF07267.6 KEG15205.1 - 0.13 10.9 9.8 0.18 10.4 6.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.9 KEG15205.1 - 6.7 4.6 15.8 10 3.9 10.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Aminotran_5 PF00266.14 KEG15206.1 - 1.7e-52 178.3 0.0 2.1e-52 178.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V MFS_1 PF07690.11 KEG15208.1 - 2e-28 99.1 44.0 1.2e-26 93.2 17.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEG15208.1 - 2.9e-06 26.1 21.2 2.8e-05 22.8 5.4 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KEG15209.1 - 2.6e-23 82.3 28.6 2.6e-23 82.3 19.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEG15209.1 - 1.1e-06 27.5 8.3 1.1e-06 27.5 5.8 2.8 2 2 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.8 KEG15209.1 - 0.00032 18.9 0.2 0.00056 18.1 0.1 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1_like PF12832.2 KEG15209.1 - 0.0035 17.1 0.0 0.02 14.6 0.0 2.3 1 0 0 1 1 1 1 MFS_1 like family Adeno_E1B_55K_N PF04623.7 KEG15209.1 - 0.034 14.6 0.1 0.078 13.4 0.1 1.5 1 0 0 1 1 1 0 Adenovirus E1B protein N-terminus Sec62 PF03839.11 KEG15209.1 - 0.58 9.5 1.7 1.2 8.5 1.2 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 DUF818 PF05677.7 KEG15210.1 - 8.7e-06 24.6 0.0 1.2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_6 PF12697.2 KEG15210.1 - 1.6e-05 24.9 0.1 3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEG15210.1 - 2.4e-05 24.1 0.0 3.7e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KEG15210.1 - 0.016 14.7 0.0 0.036 13.6 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KEG15210.1 - 0.017 14.3 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 KEG15210.1 - 0.062 12.7 0.0 0.096 12.0 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.15 KEG15210.1 - 0.072 12.6 0.2 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold IQ PF00612.22 KEG15211.1 - 0.0037 16.7 2.7 0.012 15.1 1.9 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif Dpy-30 PF05186.8 KEG15211.1 - 0.014 14.8 0.0 0.033 13.6 0.0 1.6 1 0 0 1 1 1 0 Dpy-30 motif DUF2763 PF10961.3 KEG15212.1 - 4.8 7.6 9.1 0.92 9.9 0.7 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2763) NERD PF08378.6 KEG15215.1 - 1e-22 80.5 0.4 5.1e-22 78.3 0.1 2.1 2 0 0 2 2 2 1 Nuclease-related domain Mrr_cat PF04471.7 KEG15215.1 - 0.0065 16.2 0.0 0.044 13.6 0.0 2.2 3 0 0 3 3 3 1 Restriction endonuclease tRNA-synt_1 PF00133.17 KEG15216.1 - 2.4e-215 716.0 2.0 6e-215 714.7 0.1 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KEG15216.1 - 9.9e-27 93.5 0.2 3e-26 91.9 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KEG15216.1 - 7.7e-17 61.0 2.1 4.4e-07 28.9 0.2 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 KEG15216.1 - 0.018 14.1 0.2 0.14 11.2 0.0 2.5 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain PRA1 PF03208.14 KEG15217.1 - 2.2e-05 23.8 5.1 4.7e-05 22.7 3.5 1.5 1 0 0 1 1 1 1 PRA1 family protein SWIM PF04434.12 KEG15218.1 - 0.09 12.2 0.2 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 SWIM zinc finger Cyclin_N PF00134.18 KEG15219.1 - 0.00046 19.7 0.0 0.0021 17.6 0.0 2.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF4363 PF14276.1 KEG15220.1 - 0.089 12.4 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) DAO PF01266.19 KEG15221.1 - 4.9e-21 75.0 2.6 9.1e-21 74.1 0.8 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEG15221.1 - 7e-08 32.3 0.2 2.3e-07 30.7 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KEG15221.1 - 0.00024 21.0 0.1 0.00046 20.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KEG15221.1 - 0.00027 19.9 0.2 0.00057 18.8 0.1 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KEG15221.1 - 0.0011 17.9 0.6 0.002 17.0 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KEG15221.1 - 0.0013 19.1 1.5 0.0035 17.7 0.7 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEG15221.1 - 0.0063 15.6 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 KEG15221.1 - 0.012 14.7 0.3 0.023 13.7 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 KEG15221.1 - 0.014 15.0 0.4 0.029 14.0 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 KEG15221.1 - 0.017 13.6 0.2 0.027 12.9 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.1 KEG15221.1 - 0.017 15.1 0.0 0.045 13.8 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEG15221.1 - 0.018 13.9 0.1 0.035 13.0 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 KEG15221.1 - 0.039 13.7 0.2 0.1 12.3 0.1 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding LTD PF00932.14 KEG15221.1 - 0.1 12.6 0.0 0.46 10.5 0.0 2.0 1 1 1 2 2 2 0 Lamin Tail Domain OB_NTP_bind PF07717.11 KEG15222.1 - 9.7e-22 76.9 0.0 2.2e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KEG15222.1 - 9.2e-15 54.5 0.2 1.8e-14 53.5 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KEG15222.1 - 3.8e-13 49.1 1.4 8e-13 48.0 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEG15222.1 - 3.8e-09 36.2 0.0 4.1e-08 32.9 0.0 2.7 3 1 0 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KEG15222.1 - 6.3e-05 23.1 0.0 0.00023 21.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 KEG15222.1 - 0.00093 18.1 0.0 0.0026 16.7 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein ResIII PF04851.10 KEG15222.1 - 0.014 15.2 0.0 0.44 10.3 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_29 PF13555.1 KEG15222.1 - 0.027 13.9 0.0 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain KaiC PF06745.8 KEG15222.1 - 0.027 13.5 0.0 0.055 12.5 0.0 1.4 1 0 0 1 1 1 0 KaiC FtsK_SpoIIIE PF01580.13 KEG15222.1 - 0.038 13.4 0.0 0.089 12.2 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_10 PF12846.2 KEG15222.1 - 0.045 13.1 0.0 8 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_16 PF13191.1 KEG15222.1 - 0.053 13.4 0.0 0.2 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.1 KEG15222.1 - 0.14 12.4 0.1 0.3 11.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain Metallophos PF00149.23 KEG15223.1 - 0.0035 16.7 0.1 0.011 15.1 0.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Cullin_binding PF03556.10 KEG15228.1 - 1.9e-27 95.7 1.0 2.8e-27 95.1 0.7 1.3 1 0 0 1 1 1 1 Cullin binding BT1 PF03092.11 KEG15230.1 - 4.2e-134 447.5 7.1 4.8e-134 447.3 4.9 1.0 1 0 0 1 1 1 1 BT1 family DUF755 PF05501.6 KEG15232.1 - 0.00049 20.1 24.4 0.00049 20.1 16.9 4.1 4 1 1 5 5 5 1 Domain of unknown function (DUF755) SR-25 PF10500.4 KEG15232.1 - 0.0028 17.1 35.5 0.0028 17.1 24.6 3.0 2 2 1 3 3 3 1 Nuclear RNA-splicing-associated protein Involucrin_N PF10583.4 KEG15232.1 - 3.3 8.0 9.7 23 5.3 0.1 2.8 2 0 0 2 2 2 0 Involucrin of squamous epithelia N-terminus TruD PF01142.13 KEG15233.1 - 1.7e-47 161.9 0.0 8.2e-41 139.9 0.0 3.0 3 1 0 3 3 3 2 tRNA pseudouridine synthase D (TruD) RAB3GAP2_N PF14655.1 KEG15234.1 - 1.3e-09 37.6 0.2 2.1e-09 36.8 0.1 1.3 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus MS_channel PF00924.13 KEG15235.1 - 2.2e-18 66.3 0.1 2.6e-18 66.1 0.1 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel Gcd10p PF04189.8 KEG15236.1 - 3.9e-70 236.3 0.0 6e-70 235.7 0.0 1.2 1 0 0 1 1 1 1 Gcd10p family LRR_4 PF12799.2 KEG15237.1 - 1.8e-12 46.5 0.0 5e-06 26.0 0.2 3.3 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG15237.1 - 3.2e-07 29.9 1.4 0.00023 20.8 0.2 2.8 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 KEG15237.1 - 4e-05 23.0 0.2 2.2 8.6 0.0 4.0 3 1 0 3 3 3 2 Leucine Rich Repeat LRR_6 PF13516.1 KEG15237.1 - 0.00019 21.1 0.0 5.6 7.3 0.0 4.3 3 1 1 4 4 4 2 Leucine Rich repeat LRR_7 PF13504.1 KEG15237.1 - 0.0027 17.6 1.4 0.89 10.0 0.0 3.7 3 0 0 3 3 3 1 Leucine rich repeat Sec23_trunk PF04811.10 KEG15241.1 - 5.3e-40 137.3 0.0 7.8e-40 136.7 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.10 KEG15241.1 - 1e-17 63.4 7.3 1e-17 63.4 5.1 2.1 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 KEG15241.1 - 1.6e-16 60.5 0.6 2.9e-16 59.7 0.1 1.7 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.10 KEG15241.1 - 4e-14 51.8 0.0 1.4e-13 50.1 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Gelsolin PF00626.17 KEG15241.1 - 0.11 12.2 0.4 0.3 10.8 0.0 1.9 2 0 0 2 2 2 0 Gelsolin repeat Tad PF13400.1 KEG15242.1 - 0.18 11.8 0.9 2.1 8.4 0.1 2.6 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like SNF2_N PF00176.18 KEG15243.1 - 7.6e-29 100.4 0.0 1.2e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEG15243.1 - 2.1e-13 49.9 0.0 6.8e-13 48.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEG15243.1 - 7.5e-05 22.6 0.0 0.59 9.9 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Macoilin PF09726.4 KEG15243.1 - 0.82 7.8 36.9 0.0075 14.6 11.3 2.4 2 0 0 2 2 2 0 Transmembrane protein DUF1777 PF08648.7 KEG15245.1 - 1.5e-05 24.7 18.8 1.5e-05 24.7 13.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) zf-RanBP PF00641.13 KEG15245.1 - 6.4e-05 21.9 2.1 0.00013 20.9 1.4 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others ZYG-11_interact PF05884.7 KEG15245.1 - 0.008 15.2 1.5 0.012 14.7 1.0 1.3 1 0 0 1 1 1 1 Interactor of ZYG-11 RRM_1 PF00076.17 KEG15245.1 - 0.019 14.5 0.0 0.049 13.2 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG15245.1 - 0.02 14.8 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Band_3_cyto PF07565.8 KEG15245.1 - 1.9 7.9 11.1 2.2 7.7 3.8 2.3 2 0 0 2 2 2 0 Band 3 cytoplasmic domain IPP-2 PF04979.9 KEG15246.1 - 8.2e-06 26.0 6.8 3.7e-05 23.9 4.7 2.1 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) CDC45 PF02724.9 KEG15246.1 - 2.3 6.1 10.4 3.2 5.6 7.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.6 KEG15246.1 - 7.4 5.4 7.6 15 4.4 5.3 1.5 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) TPR_11 PF13414.1 KEG15248.1 - 5.8e-17 61.0 16.5 7.1e-06 25.5 1.7 6.0 3 2 3 6 6 6 5 TPR repeat TPR_16 PF13432.1 KEG15248.1 - 1.4e-14 54.2 1.4 7.2e-07 29.7 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEG15248.1 - 2e-13 50.4 13.4 0.0004 20.6 0.1 5.9 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 KEG15248.1 - 1.4e-12 47.3 5.7 0.00067 19.5 0.2 6.5 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEG15248.1 - 4.3e-12 44.9 13.6 0.0019 17.9 0.0 8.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEG15248.1 - 1.9e-10 40.3 1.1 0.0041 17.6 0.0 6.9 5 2 3 8 8 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEG15248.1 - 1.5e-06 27.5 5.1 7.9 6.5 0.0 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.1 KEG15248.1 - 2.3e-06 27.6 12.6 0.038 14.4 0.0 7.3 9 0 0 9 9 7 1 Tetratricopeptide repeat Apc3 PF12895.2 KEG15248.1 - 5.4e-06 26.4 17.8 0.00066 19.7 3.3 5.1 2 2 5 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KEG15248.1 - 0.00031 20.5 2.0 0.0053 16.5 0.5 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEG15248.1 - 0.0015 18.0 19.8 0.19 11.3 0.0 8.5 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_10 PF13374.1 KEG15248.1 - 0.0047 16.8 6.3 8.8 6.4 0.0 6.0 6 1 1 7 7 7 0 Tetratricopeptide repeat BTAD PF03704.12 KEG15248.1 - 0.016 15.5 0.5 0.18 12.0 0.1 2.8 3 0 0 3 3 3 0 Bacterial transcriptional activator domain Bac_luciferase PF00296.15 KEG15248.1 - 0.053 12.6 0.0 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 Luciferase-like monooxygenase Fis1_TPR_C PF14853.1 KEG15248.1 - 0.19 11.6 15.8 1.6 8.6 0.0 5.1 4 1 2 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat PPR_3 PF13812.1 KEG15248.1 - 0.34 11.3 1.5 16 6.0 0.0 4.0 4 0 0 4 4 4 0 Pentatricopeptide repeat domain TPR_8 PF13181.1 KEG15248.1 - 6.6 6.7 9.6 12 5.9 0.0 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat RNA_pol_A_bac PF01000.21 KEG15249.1 - 3.3e-22 78.7 0.0 5.8e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KEG15249.1 - 8.9e-13 47.1 0.0 1.1e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_7 PF12838.2 KEG15249.1 - 0.041 14.2 0.7 0.041 14.2 0.5 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4 PF00037.22 KEG15249.1 - 0.057 13.0 1.9 0.087 12.4 0.4 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_9 PF13187.1 KEG15249.1 - 0.085 13.1 0.9 0.085 13.1 0.6 2.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain IQ PF00612.22 KEG15250.1 - 0.0053 16.2 2.8 0.0053 16.2 1.9 3.3 3 0 0 3 3 3 2 IQ calmodulin-binding motif PC_rep PF01851.17 KEG15251.1 - 4.6e-20 70.6 27.0 6.3e-06 26.1 0.2 10.0 11 0 0 11 11 11 5 Proteasome/cyclosome repeat HEAT_EZ PF13513.1 KEG15251.1 - 0.1 13.0 3.6 0.85 10.1 0.1 4.1 5 0 0 5 5 5 0 HEAT-like repeat VWA_2 PF13519.1 KEG15252.1 - 1.1e-11 45.1 0.9 2e-11 44.2 0.6 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KEG15252.1 - 0.00036 20.3 0.1 0.00058 19.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain NYN_YacP PF05991.6 KEG15252.1 - 0.086 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 YacP-like NYN domain DOCK-C2 PF14429.1 KEG15253.1 - 8.4e-27 93.9 0.0 1.6e-26 93.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Fibrinogen_BP PF08017.6 KEG15253.1 - 0.17 10.0 32.6 0.28 9.3 22.6 1.2 1 0 0 1 1 1 0 Fibrinogen binding protein WD40 PF00400.27 KEG15254.1 - 3.7e-13 48.7 13.4 0.00061 19.5 0.2 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Ras PF00071.17 KEG15255.1 - 7.6e-35 119.6 0.1 8.7e-35 119.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEG15255.1 - 9.3e-13 48.7 0.0 1.4e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEG15255.1 - 6.2e-09 35.3 0.0 8e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KEG15255.1 - 0.00027 20.8 0.0 0.0004 20.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 KEG15255.1 - 0.011 15.1 0.0 0.35 10.3 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CppA_C PF14507.1 KEG15255.1 - 0.017 15.2 0.1 1.3 9.2 0.0 2.3 1 1 1 2 2 2 0 CppA C-terminal Gtr1_RagA PF04670.7 KEG15255.1 - 0.044 12.9 0.1 0.055 12.5 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Dynamin_N PF00350.18 KEG15255.1 - 0.14 12.0 0.3 2.3 7.9 0.1 2.3 1 1 0 2 2 2 0 Dynamin family Syntaxin_2 PF14523.1 KEG15257.1 - 1.9e-11 43.8 1.1 1.9e-11 43.8 0.8 2.4 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 KEG15257.1 - 2.2e-09 36.8 5.0 2.2e-09 36.8 3.5 2.1 2 0 0 2 2 2 1 SNARE domain Spc7 PF08317.6 KEG15257.1 - 0.002 16.8 0.5 0.002 16.8 0.4 2.0 2 0 0 2 2 2 1 Spc7 kinetochore protein Synaptobrevin PF00957.16 KEG15257.1 - 0.0034 16.9 3.6 0.022 14.3 0.9 2.9 3 0 0 3 3 3 1 Synaptobrevin MCPsignal PF00015.16 KEG15257.1 - 0.017 14.6 5.1 0.031 13.8 0.8 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1759 PF03564.10 KEG15257.1 - 0.037 13.8 4.3 1.4 8.6 0.1 2.6 2 2 1 3 3 3 0 Protein of unknown function (DUF1759) DUF1664 PF07889.7 KEG15257.1 - 0.62 9.8 3.8 1.3 8.7 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2956 PF11169.3 KEG15257.1 - 1.2 9.1 0.0 1.2 9.1 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2956) V_ATPase_I PF01496.14 KEG15257.1 - 1.7 6.4 5.2 0.47 8.2 0.5 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family tRNA-synt_1b PF00579.20 KEG15258.1 - 5.1e-22 78.3 0.0 1.5e-21 76.7 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Ribosomal_L3 PF00297.17 KEG15261.1 - 7.8e-13 48.4 0.1 1.3e-12 47.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L3 SPT16 PF08644.6 KEG15262.1 - 6.7e-33 113.6 2.3 9.5e-33 113.1 0.1 2.1 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.19 KEG15262.1 - 1.4e-19 70.5 0.0 2.4e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 KEG15262.1 - 1.8e-13 50.2 0.0 6.1e-13 48.5 0.0 1.9 2 0 0 2 2 2 1 Histone chaperone Rttp106-like YL1 PF05764.8 KEG15262.1 - 5.9 6.4 22.8 0.21 11.1 11.5 1.7 2 0 0 2 2 2 0 YL1 nuclear protein Nop14 PF04147.7 KEG15262.1 - 6.3 4.5 21.7 15 3.3 15.1 1.5 1 0 0 1 1 1 0 Nop14-like family ECH PF00378.15 KEG15263.1 - 1.3e-36 125.9 0.0 1.6e-36 125.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Pkinase PF00069.20 KEG15265.1 - 1.6e-57 194.6 0.0 3.7e-57 193.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG15265.1 - 2.4e-41 141.5 0.0 1.3e-40 139.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEG15265.1 - 2.7e-06 26.5 0.0 4.7e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KEG15265.1 - 0.0021 17.1 0.0 0.0037 16.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEG15265.1 - 0.15 11.7 0.1 0.38 10.4 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF2615 PF11027.3 KEG15266.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) DUF1201 PF06716.6 KEG15266.1 - 0.22 11.3 3.4 0.37 10.6 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1201) APH PF01636.18 KEG15268.1 - 2.8e-08 33.7 0.4 1.3e-07 31.5 0.3 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family ChpXY PF10216.4 KEG15268.1 - 0.059 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 CO2 hydration protein (ChpXY) DUF3107 PF11305.3 KEG15268.1 - 0.096 12.5 0.0 0.41 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3107) CENP-F_leu_zip PF10473.4 KEG15269.1 - 0.054 13.3 0.3 0.09 12.6 0.2 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 H-kinase_dim PF02895.9 KEG15269.1 - 0.097 13.0 0.1 0.24 11.7 0.1 1.7 1 0 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain zf-MYND PF01753.13 KEG15271.1 - 5.1e-06 26.2 6.7 5.1e-06 26.2 4.7 2.9 3 0 0 3 3 3 1 MYND finger SET PF00856.23 KEG15271.1 - 0.15 12.3 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 SET domain Toxin_34 PF08396.5 KEG15271.1 - 4.4 7.9 11.4 0.33 11.5 1.1 2.8 3 0 0 3 3 3 0 Spider toxin omega agatoxin/Tx1 family WD40 PF00400.27 KEG15274.1 - 6.3e-15 54.4 2.5 7.3e-06 25.6 0.1 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat Ribosomal_L6e PF01159.14 KEG15275.1 - 3e-32 111.0 0.6 3e-32 111.0 0.4 2.1 2 1 0 2 2 2 1 Ribosomal protein L6e KOW PF00467.24 KEG15275.1 - 0.0056 16.3 0.1 0.041 13.6 0.0 2.4 3 0 0 3 3 3 1 KOW motif HK97-gp10_like PF04883.7 KEG15275.1 - 0.43 11.5 5.6 5 8.1 0.1 2.4 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component DUF2823 PF11034.3 KEG15275.1 - 0.88 9.7 13.8 0.65 10.1 3.8 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2823) PTR2 PF00854.16 KEG15276.1 - 4.9e-22 78.2 14.3 8.5e-12 44.5 4.3 2.2 2 0 0 2 2 2 2 POT family MFS_1 PF07690.11 KEG15276.1 - 0.0003 19.6 48.0 0.0069 15.1 9.6 3.6 1 1 1 3 3 3 2 Major Facilitator Superfamily IncA PF04156.9 KEG15276.1 - 0.0078 15.8 9.3 0.046 13.3 0.2 3.5 3 1 0 3 3 3 2 IncA protein TPR_11 PF13414.1 KEG15277.1 - 0.00031 20.3 9.7 0.0027 17.3 0.9 2.9 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 KEG15277.1 - 0.001 18.7 4.1 0.73 9.8 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEG15277.1 - 0.0011 19.6 0.4 0.0032 18.0 0.3 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEG15277.1 - 0.0025 17.3 1.7 0.88 9.2 0.1 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 KEG15277.1 - 0.059 13.5 1.9 0.11 12.8 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 KEG15277.1 - 0.3 11.2 3.2 0.64 10.1 2.1 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 ERG4_ERG24 PF01222.12 KEG15279.1 - 1.1e-105 353.6 17.8 1.4e-105 353.3 12.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family WD40 PF00400.27 KEG15280.1 - 0.26 11.2 2.5 14 5.7 0.0 4.3 5 0 0 5 5 5 0 WD domain, G-beta repeat EF-hand_7 PF13499.1 KEG15283.1 - 3.1e-08 33.6 0.3 1.2e-07 31.7 0.1 1.9 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KEG15283.1 - 3.3e-06 26.4 0.0 7.2e-05 22.3 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 KEG15283.1 - 0.0022 17.1 0.0 0.014 14.6 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KEG15283.1 - 0.0051 16.3 0.1 0.027 14.0 0.0 2.2 2 1 1 3 3 3 1 EF-hand domain pair Apolipoprotein PF01442.13 KEG15284.1 - 0.08 12.4 4.4 0.15 11.5 3.1 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Cauli_AT PF03233.8 KEG15284.1 - 1.5 8.5 4.6 28 4.3 0.0 3.0 2 1 1 3 3 3 0 Aphid transmission protein IFT57 PF10498.4 KEG15285.1 - 5e-127 423.5 0.1 5.7e-127 423.3 0.1 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 AKNA PF12443.3 KEG15285.1 - 0.0033 17.4 8.7 0.016 15.2 1.8 2.5 1 1 1 2 2 2 1 AT-hook-containing transcription factor AAA_13 PF13166.1 KEG15285.1 - 0.01 14.3 3.5 0.013 13.9 2.4 1.1 1 0 0 1 1 1 0 AAA domain Tropomyosin PF00261.15 KEG15285.1 - 0.015 14.4 8.4 0.031 13.3 5.8 1.5 1 1 0 1 1 1 0 Tropomyosin Peptidase_M75 PF09375.5 KEG15285.1 - 0.023 14.0 0.8 0.035 13.4 0.5 1.3 1 0 0 1 1 1 0 Imelysin Apolipoprotein PF01442.13 KEG15285.1 - 0.024 14.1 11.5 0.027 13.9 6.8 1.7 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain CR6_interact PF10147.4 KEG15285.1 - 0.032 13.5 3.1 0.053 12.8 2.2 1.4 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 V_ATPase_I PF01496.14 KEG15285.1 - 0.05 11.4 5.2 0.066 11.0 3.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mnd1 PF03962.10 KEG15285.1 - 0.059 13.0 5.6 0.12 12.0 3.9 1.5 1 0 0 1 1 1 0 Mnd1 family TPR_MLP1_2 PF07926.7 KEG15285.1 - 0.064 13.0 7.9 0.11 12.2 5.5 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein MCPsignal PF00015.16 KEG15285.1 - 0.086 12.3 4.6 0.075 12.5 1.5 1.8 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain IncA PF04156.9 KEG15285.1 - 0.1 12.2 12.0 0.23 11.0 5.8 2.1 1 1 1 2 2 2 0 IncA protein Laminin_II PF06009.7 KEG15285.1 - 0.18 11.5 8.2 6.5 6.5 5.7 2.4 1 1 0 1 1 1 0 Laminin Domain II Prominin PF05478.6 KEG15285.1 - 0.39 8.1 5.2 0.53 7.7 3.6 1.1 1 0 0 1 1 1 0 Prominin FUSC PF04632.7 KEG15285.1 - 0.39 9.0 1.5 0.56 8.5 1.0 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4515 PF14988.1 KEG15285.1 - 0.83 9.2 11.6 1.5 8.4 8.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4515) DUF745 PF05335.8 KEG15285.1 - 0.98 8.9 7.1 2.5 7.5 2.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Spc7 PF08317.6 KEG15285.1 - 1.1 7.8 10.3 3.9 6.0 7.1 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF2203 PF09969.4 KEG15285.1 - 1.6 8.9 6.2 15 5.8 0.4 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) COG2 PF06148.6 KEG15285.1 - 3.1 7.6 8.6 7.7 6.3 1.3 2.6 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 GAS PF13851.1 KEG15285.1 - 3.7 6.7 12.2 1.7 7.7 5.5 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Phage_GPO PF05929.6 KEG15285.1 - 4.8 6.3 8.5 11 5.1 2.0 2.1 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF948 PF06103.6 KEG15285.1 - 4.9 7.0 7.9 3.4 7.5 1.2 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.7 KEG15285.1 - 6.2 6.6 8.7 2.1 8.1 2.7 2.3 2 1 1 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Apc3 PF12895.2 KEG15287.1 - 0.00041 20.4 0.1 0.045 13.9 0.0 3.0 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KEG15287.1 - 0.011 15.4 0.1 11 6.1 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.15 KEG15287.1 - 0.075 13.0 0.0 89 3.4 0.0 3.7 3 0 0 3 3 3 0 PPR repeat TPR_14 PF13428.1 KEG15287.1 - 0.11 13.2 0.1 6.4 7.7 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3755 PF12579.3 KEG15287.1 - 2.2 7.7 4.5 37 3.8 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3755) RRM_1 PF00076.17 KEG15288.1 - 1.9e-12 46.6 0.2 2.6e-09 36.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG15288.1 - 1.2e-11 44.4 0.3 3.9e-07 29.9 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG15288.1 - 8.4e-09 35.1 0.1 6.4e-05 22.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pox_TAA1 PF03295.9 KEG15288.1 - 0.047 13.3 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Poxvirus trans-activator protein A1 C-terminal API5 PF05918.6 KEG15288.1 - 2.4 6.5 4.5 2.7 6.3 3.1 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) IGR PF09597.5 KEG15289.1 - 0.0024 17.7 0.0 0.0046 16.8 0.0 1.5 1 0 0 1 1 1 1 IGR protein motif BRE1 PF08647.6 KEG15290.1 - 1.8e-19 69.5 12.0 1.8e-19 69.5 8.3 10.9 4 2 5 10 10 10 2 BRE1 E3 ubiquitin ligase AAA_13 PF13166.1 KEG15290.1 - 0.0016 16.9 24.1 0.0016 16.9 16.7 6.3 1 1 4 5 5 5 3 AAA domain Reo_sigmaC PF04582.7 KEG15290.1 - 0.21 10.7 42.0 0.35 9.9 0.9 6.9 2 2 7 9 9 9 0 Reovirus sigma C capsid protein D-aminoacyl_C PF07908.7 KEG15291.1 - 0.036 13.3 0.0 0.075 12.3 0.0 1.4 1 0 0 1 1 1 0 D-aminoacylase, C-terminal region SynMuv_product PF06047.6 KEG15292.1 - 6.4e-12 45.1 1.4 1.4e-11 44.0 0.9 1.5 1 0 0 1 1 1 1 Ras-induced vulval development antagonist Extensin_2 PF04554.8 KEG15293.1 - 1e-06 28.4 85.6 3.3e-05 23.6 26.0 2.9 1 1 2 3 3 3 3 Extensin-like region WD40 PF00400.27 KEG15294.1 - 0.00031 20.4 1.2 0.081 12.8 0.2 3.7 3 0 0 3 3 3 1 WD domain, G-beta repeat FYVE PF01363.16 KEG15295.1 - 0.00099 18.9 10.4 0.0044 16.8 6.8 2.0 1 1 1 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.11 KEG15295.1 - 0.01 15.7 5.1 0.014 15.3 3.6 1.3 1 1 0 1 1 1 0 FYVE-type zinc finger C1_1 PF00130.17 KEG15295.1 - 0.65 9.7 9.3 0.1 12.3 4.0 1.5 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.2 KEG15295.1 - 3.9 7.3 14.0 1.3e+02 2.5 9.7 2.5 1 1 0 1 1 1 0 Double zinc ribbon TerY-C PF15616.1 KEG15295.1 - 4 7.3 9.4 5.3 6.9 0.2 2.2 1 1 1 2 2 2 0 TerY-C metal binding domain RtcB PF01139.12 KEG15296.1 - 1.3e-121 406.5 0.3 1.5e-121 406.3 0.2 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB ThiF PF00899.16 KEG15297.1 - 2.6e-28 98.5 0.0 5e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 KEG15297.1 - 1.4e-06 28.4 0.0 0.00026 21.0 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 KEG15297.1 - 0.00036 19.5 0.0 0.00063 18.7 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 KEG15297.1 - 0.021 13.9 0.0 0.7 9.0 0.0 2.2 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polysacc_deac_1 PF01522.16 KEG15297.1 - 0.093 12.3 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide deacetylase Bul1_C PF04426.7 KEG15298.1 - 0.27 10.3 4.5 0.47 9.6 3.1 1.3 1 0 0 1 1 1 0 Bul1 C terminus DUF383 PF04063.9 KEG15299.1 - 0.093 12.2 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF383) dsrm PF00035.20 KEG15300.1 - 4.4e-15 56.0 0.0 7e-06 26.5 0.0 5.2 5 0 0 5 5 5 2 Double-stranded RNA binding motif HA2 PF04408.18 KEG15300.1 - 4.6e-14 52.2 0.1 1.3e-13 50.8 0.1 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KEG15300.1 - 1.3e-11 44.1 0.2 5e-11 42.2 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEG15300.1 - 1.4e-10 40.9 0.0 4.8e-10 39.1 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KEG15300.1 - 2e-06 27.9 1.0 1e-05 25.6 0.1 2.6 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 KEG15300.1 - 0.0024 17.6 0.1 0.041 13.6 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain DND1_DSRM PF14709.1 KEG15300.1 - 0.0033 17.6 0.2 0.012 15.8 0.1 2.1 2 0 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_14 PF13173.1 KEG15300.1 - 0.0038 17.1 0.4 0.089 12.6 0.2 2.8 1 1 0 1 1 1 1 AAA domain OB_NTP_bind PF07717.11 KEG15300.1 - 0.0058 16.4 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold KaiC PF06745.8 KEG15300.1 - 0.017 14.2 0.0 0.036 13.1 0.0 1.5 1 0 0 1 1 1 0 KaiC T2SE PF00437.15 KEG15300.1 - 0.022 13.6 0.0 0.051 12.4 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.7 KEG15300.1 - 0.076 12.6 0.2 0.37 10.4 0.0 2.1 2 0 0 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 KEG15300.1 - 0.076 12.7 0.0 0.24 11.0 0.0 1.8 1 0 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 KEG15300.1 - 0.08 13.2 0.2 0.32 11.2 0.0 2.1 2 0 0 2 2 2 0 ABC transporter PhoH PF02562.11 KEG15300.1 - 0.085 12.0 0.0 0.2 10.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.17 KEG15300.1 - 0.19 10.5 0.0 0.47 9.2 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_23 PF13476.1 KEG15300.1 - 4 7.7 5.5 7.1 6.8 0.9 2.9 2 1 1 3 3 3 0 AAA domain DRMBL PF07522.9 KEG15302.1 - 1.6e-17 63.5 0.0 4.1e-17 62.2 0.0 1.7 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 KEG15302.1 - 9.7e-09 35.0 0.0 2.8e-08 33.5 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.7 KEG15302.1 - 0.086 12.6 0.0 0.36 10.6 0.0 2.0 2 0 0 2 2 2 0 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 KEG15302.1 - 0.4 10.3 3.1 4.7 6.8 2.2 2.2 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily P53_C PF11619.3 KEG15303.1 - 0.081 12.6 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Transcription factor P53 - C terminal domain DUF4379 PF14311.1 KEG15304.1 - 1.2e-15 57.0 0.8 2.2e-15 56.2 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4379) HypA PF01155.14 KEG15304.1 - 0.25 11.0 1.3 0.39 10.4 0.2 1.7 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-UBP PF02148.14 KEG15305.1 - 2.5e-19 69.1 1.6 3.1e-18 65.6 1.7 2.3 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein zf-C4H2 PF10146.4 KEG15305.1 - 2.4 8.1 6.8 0.11 12.5 0.6 1.7 2 0 0 2 2 2 0 Zinc finger-containing protein UPF0054 PF02130.12 KEG15307.1 - 5.1e-33 113.4 0.0 7.1e-33 112.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 LRR_4 PF12799.2 KEG15309.1 - 6.4e-08 32.0 0.0 0.0021 17.6 0.0 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG15309.1 - 1.8e-05 24.3 5.4 0.0003 20.4 0.2 3.2 2 1 2 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 KEG15309.1 - 1.9e-05 24.2 0.2 0.4 10.8 0.0 4.3 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.28 KEG15309.1 - 6.7e-05 22.3 1.7 1.2 9.4 0.2 4.3 3 1 0 3 3 3 2 Leucine Rich Repeat LRR_7 PF13504.1 KEG15309.1 - 0.0014 18.4 6.3 9.2 6.9 0.1 4.9 4 2 1 5 5 5 2 Leucine rich repeat DUF4610 PF15384.1 KEG15309.1 - 0.1 12.0 0.0 0.23 10.9 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4610) Complex1_LYR PF05347.10 KEG15310.1 - 0.0072 16.0 1.1 0.012 15.3 0.8 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) CENP-L PF13092.1 KEG15310.1 - 0.091 12.5 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 DUF1244 PF06844.6 KEG15310.1 - 0.094 12.5 0.3 0.22 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1244) UNC-79 PF14776.1 KEG15310.1 - 0.096 11.0 0.1 0.1 10.9 0.1 1.0 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 p450 PF00067.17 KEG15311.1 - 2.7e-58 197.6 0.0 3.9e-58 197.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1477 PF07346.6 KEG15311.1 - 0.11 12.5 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1477) AAA PF00004.24 KEG15313.1 - 4e-36 124.1 0.0 8.7e-36 123.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 KEG15313.1 - 1e-07 31.7 0.0 5.8e-07 29.3 0.0 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_5 PF07728.9 KEG15313.1 - 1.2e-05 25.0 0.1 4.9e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KEG15313.1 - 2e-05 25.3 0.0 5.9e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEG15313.1 - 0.00015 21.4 0.0 0.00046 19.8 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 KEG15313.1 - 0.00025 20.7 0.2 0.35 10.4 0.0 2.3 1 1 1 2 2 2 2 NACHT domain AAA_16 PF13191.1 KEG15313.1 - 0.0008 19.4 0.1 0.014 15.4 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 KEG15313.1 - 0.0009 18.3 0.1 0.0054 15.8 0.1 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KEG15313.1 - 0.0015 18.6 0.1 0.055 13.6 0.1 2.6 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KEG15313.1 - 0.0086 15.5 0.1 0.019 14.4 0.1 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.1 KEG15313.1 - 0.0093 15.5 0.1 0.025 14.1 0.1 1.6 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KEG15313.1 - 0.011 14.9 0.0 0.038 13.1 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 KEG15313.1 - 0.011 14.4 0.0 0.019 13.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_25 PF13481.1 KEG15313.1 - 0.028 13.8 0.4 0.082 12.3 0.3 1.7 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KEG15313.1 - 0.029 14.2 0.0 0.067 13.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KEG15313.1 - 0.039 13.8 0.0 0.075 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KEG15313.1 - 0.059 12.6 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_2 PF07724.9 KEG15313.1 - 0.1 12.4 0.0 0.52 10.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) KaiC PF06745.8 KEG15313.1 - 0.12 11.4 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 KaiC DUF815 PF05673.8 KEG15313.1 - 0.18 10.7 0.0 0.33 9.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) VPS9 PF02204.13 KEG15314.1 - 1.6e-05 24.8 0.0 0.00011 22.1 0.0 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain NUP PF06516.6 KEG15315.1 - 0.017 13.9 0.2 0.029 13.1 0.1 1.4 1 0 0 1 1 1 0 Purine nucleoside permease (NUP) PGA_cap PF09587.5 KEG15316.1 - 0.065 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap Tyr_Deacylase PF02580.11 KEG15318.1 - 3.7e-40 137.2 0.0 4.3e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase DUF2892 PF11127.3 KEG15318.1 - 0.058 13.2 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) PocR PF10114.4 KEG15318.1 - 0.061 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Sensory domain found in PocR Complex1_LYR PF05347.10 KEG15319.1 - 0.0036 17.0 0.1 0.0087 15.8 0.0 1.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) POLO_box PF00659.13 KEG15319.1 - 0.034 14.1 0.2 0.09 12.7 0.0 1.8 2 1 0 2 2 2 0 POLO box duplicated region RyR PF02026.11 KEG15319.1 - 0.047 13.7 0.1 0.35 10.9 0.0 2.2 2 1 0 2 2 2 0 RyR domain Aldose_epim PF01263.15 KEG15320.1 - 1.9e-37 129.0 0.2 6.3e-37 127.2 0.1 1.7 1 1 0 1 1 1 1 Aldose 1-epimerase HECT PF00632.20 KEG15321.1 - 1.2e-14 54.2 0.1 0.00042 19.5 0.0 5.9 6 0 0 6 6 6 6 HECT-domain (ubiquitin-transferase) Lactamase_B PF00753.22 KEG15322.1 - 2.5e-11 43.5 2.9 4.5e-11 42.7 2.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KEG15322.1 - 0.044 13.3 0.0 0.08 12.4 0.0 1.4 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Beta-Casp PF10996.3 KEG15323.1 - 1.9e-32 111.8 0.0 4.3e-32 110.7 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 KEG15323.1 - 6.3e-21 74.9 0.2 1.3e-20 73.8 0.0 1.6 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily CPSF73-100_C PF11718.3 KEG15323.1 - 3.5e-11 42.8 0.1 6.8e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Lactamase_B_2 PF12706.2 KEG15323.1 - 8.7e-11 41.7 0.1 2.3e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 KEG15323.1 - 4.3e-09 36.0 0.0 8.6e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 KEG15323.1 - 3.8e-05 23.4 0.0 0.00011 21.9 0.0 1.8 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Topoisom_I_N PF02919.10 KEG15324.1 - 4.5e-94 313.7 2.8 4.5e-94 313.7 1.9 2.8 2 1 1 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 KEG15324.1 - 5.1e-82 274.4 1.0 8.7e-82 273.7 0.7 1.4 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core LRR_8 PF13855.1 KEG15325.1 - 6.2e-05 22.6 2.6 0.00015 21.4 1.8 1.7 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.2 KEG15325.1 - 0.0004 19.9 2.8 0.0022 17.5 0.1 2.7 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 KEG15325.1 - 0.00071 19.1 0.1 0.0014 18.2 0.1 1.4 1 0 0 1 1 1 1 Leucine-rich repeat DUF4200 PF13863.1 KEG15325.1 - 0.064 13.2 3.3 0.14 12.0 2.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) LRR_1 PF00560.28 KEG15325.1 - 0.1 12.6 1.9 4.7 7.6 0.0 3.4 2 1 0 2 2 2 0 Leucine Rich Repeat DUF724 PF05266.9 KEG15325.1 - 2.2 7.8 5.5 5 6.6 3.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) LRR_7 PF13504.1 KEG15325.1 - 2.7 8.5 4.9 8.7 7.0 0.0 3.7 3 0 0 3 3 3 0 Leucine rich repeat Neuromodulin PF06614.6 KEG15325.1 - 2.9 7.7 14.6 0.63 9.9 7.3 2.0 2 0 0 2 2 2 0 Neuromodulin zf-RanBP PF00641.13 KEG15326.1 - 0.00013 21.0 2.4 0.00023 20.1 1.7 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-tcix PF14952.1 KEG15326.1 - 0.37 10.1 4.1 0.89 8.9 2.8 1.6 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding Amidinotransf PF02274.12 KEG15327.1 - 2.4e-15 56.3 0.0 1.6e-14 53.6 0.0 2.2 1 1 0 1 1 1 1 Amidinotransferase LRR_6 PF13516.1 KEG15328.1 - 4.6e-06 26.1 0.2 0.0059 16.5 0.0 3.1 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.2 KEG15328.1 - 0.0082 15.7 0.1 0.023 14.3 0.0 1.8 1 1 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG15328.1 - 0.12 12.1 0.1 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 Leucine rich repeat TPR_12 PF13424.1 KEG15329.1 - 4.7e-56 186.6 46.7 1.2e-15 57.1 0.2 5.7 1 1 6 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.1 KEG15329.1 - 1.4e-24 85.2 28.1 7.9e-08 31.9 0.0 7.5 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.1 KEG15329.1 - 2.1e-16 59.3 16.1 1.5e-06 27.7 0.0 4.9 3 2 3 6 6 6 4 TPR repeat TPR_8 PF13181.1 KEG15329.1 - 2.1e-15 55.2 15.5 2.3e-06 26.9 0.6 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 KEG15329.1 - 1.9e-10 39.7 21.2 0.00014 21.3 0.0 6.5 8 1 1 9 9 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 KEG15329.1 - 1e-07 31.9 16.0 2.6 8.8 0.0 6.9 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 KEG15329.1 - 1.7e-05 25.3 15.7 0.011 16.3 1.8 5.1 4 1 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEG15329.1 - 2e-05 24.1 22.6 0.33 10.9 0.1 7.2 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEG15329.1 - 2.5e-05 23.6 19.9 0.12 12.0 0.1 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 KEG15329.1 - 7.5e-05 22.6 9.8 0.24 11.7 0.0 6.1 6 1 0 6 6 5 1 Tetratricopeptide repeat DUF2225 PF09986.4 KEG15329.1 - 8.3e-05 22.1 4.4 0.065 12.6 0.2 4.0 1 1 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) Rapsyn_N PF10579.4 KEG15329.1 - 0.00027 20.6 2.8 4.1 7.2 0.1 3.7 2 1 2 4 4 4 2 Rapsyn N-terminal myristoylation and linker region DUF3856 PF12968.2 KEG15329.1 - 0.0024 17.7 2.2 0.19 11.5 0.0 3.8 3 1 1 4 4 4 1 Domain of Unknown Function (DUF3856) DUF627 PF04781.7 KEG15329.1 - 0.0031 17.1 2.8 2.5 7.7 0.0 3.9 3 2 1 4 4 4 1 Protein of unknown function (DUF627) GTPase_Cys_C PF12631.2 KEG15329.1 - 0.0077 16.6 2.1 0.066 13.6 0.1 3.4 3 1 1 4 4 3 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE TPR_19 PF14559.1 KEG15329.1 - 0.037 14.3 9.2 0.61 10.4 0.1 4.4 3 2 2 5 5 5 0 Tetratricopeptide repeat SusD PF07980.6 KEG15329.1 - 0.1 12.0 1.0 0.45 9.9 0.1 2.0 2 0 0 2 2 2 0 SusD family TPR_6 PF13174.1 KEG15329.1 - 0.39 11.2 15.9 7.4 7.2 0.4 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat PPR PF01535.15 KEG15329.1 - 1.4 9.0 12.5 1.5 8.9 0.1 5.2 7 0 0 7 7 7 0 PPR repeat TIP49 PF06068.8 KEG15330.1 - 6.5e-185 614.5 1.4 7.6e-185 614.3 1.0 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 KEG15330.1 - 1.3e-11 44.0 0.7 5.5e-08 32.1 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 KEG15330.1 - 2.1e-11 44.1 0.9 3.9e-07 30.3 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEG15330.1 - 1.4e-06 28.4 0.3 0.066 13.3 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 KEG15330.1 - 2.2e-06 27.8 0.3 0.00066 19.7 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.16 KEG15330.1 - 0.00092 18.4 0.2 0.041 13.0 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KEG15330.1 - 0.0011 18.7 0.0 0.0038 16.9 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 KEG15330.1 - 0.0014 18.4 0.1 0.093 12.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KEG15330.1 - 0.0015 17.9 0.0 0.0028 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KEG15330.1 - 0.0031 16.9 0.6 0.029 13.7 0.1 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.1 KEG15330.1 - 0.0036 17.1 0.0 0.017 15.0 0.0 2.1 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 KEG15330.1 - 0.0069 17.1 0.0 0.028 15.2 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KEG15330.1 - 0.0072 16.2 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KEG15330.1 - 0.012 15.8 0.1 0.15 12.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KEG15330.1 - 0.03 14.2 0.0 8.3 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 KEG15330.1 - 0.036 13.6 0.1 0.11 12.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain MinE PF03776.9 KEG15330.1 - 0.038 13.5 0.3 0.09 12.3 0.2 1.6 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE Zeta_toxin PF06414.7 KEG15330.1 - 0.081 12.0 0.5 0.22 10.5 0.1 1.9 2 0 0 2 2 2 0 Zeta toxin ResIII PF04851.10 KEG15330.1 - 0.12 12.1 1.0 2.5 7.9 0.1 2.4 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit SET PF00856.23 KEG15331.1 - 1.8e-06 28.3 0.0 1.2e-05 25.6 0.0 2.0 1 1 0 1 1 1 1 SET domain AAA PF00004.24 KEG15332.1 - 1.2e-50 171.1 0.0 4.3e-38 130.4 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 KEG15332.1 - 7.3e-19 67.5 0.2 1.6e-18 66.4 0.1 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 KEG15332.1 - 2.5e-08 34.1 1.9 0.011 15.7 0.0 4.3 3 2 1 5 5 5 2 AAA ATPase domain AAA_22 PF13401.1 KEG15332.1 - 5.2e-08 33.1 0.1 0.0095 16.0 0.0 3.4 2 1 1 3 3 2 2 AAA domain AAA_33 PF13671.1 KEG15332.1 - 1.8e-07 31.1 0.0 0.0024 17.7 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KEG15332.1 - 6.9e-06 25.4 0.0 0.0024 17.3 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KEG15332.1 - 2.7e-05 24.4 0.7 0.54 10.5 0.0 4.1 4 0 0 4 4 3 1 ABC transporter DUF815 PF05673.8 KEG15332.1 - 3.9e-05 22.7 0.0 0.067 12.0 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_14 PF13173.1 KEG15332.1 - 4.7e-05 23.2 0.0 0.15 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KEG15332.1 - 0.00016 21.3 0.0 0.85 9.4 0.0 3.2 2 0 0 2 2 2 2 Part of AAA domain Zeta_toxin PF06414.7 KEG15332.1 - 0.00018 20.6 0.0 0.12 11.4 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin NACHT PF05729.7 KEG15332.1 - 0.00025 20.7 2.8 0.3 10.7 0.0 3.7 3 1 1 4 4 3 1 NACHT domain AAA_5 PF07728.9 KEG15332.1 - 0.00033 20.4 0.0 0.3 10.8 0.0 3.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 KEG15332.1 - 0.00039 20.4 0.0 0.23 11.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KEG15332.1 - 0.0005 19.5 0.8 5.4 6.3 0.0 4.5 3 1 2 5 5 5 0 AAA domain Sigma54_activ_2 PF14532.1 KEG15332.1 - 0.00057 19.9 0.0 1.8 8.6 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_17 PF13207.1 KEG15332.1 - 0.00068 20.4 0.0 0.035 14.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KEG15332.1 - 0.0013 18.4 0.0 6.4 6.3 0.0 3.5 2 2 1 3 3 3 0 Archaeal ATPase Vps4_C PF09336.5 KEG15332.1 - 0.002 18.0 0.2 0.012 15.5 0.1 2.4 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_23 PF13476.1 KEG15332.1 - 0.0026 18.1 0.0 0.084 13.1 0.1 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KEG15332.1 - 0.0028 17.0 0.0 0.97 8.8 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein T2SE PF00437.15 KEG15332.1 - 0.0041 16.0 0.0 0.24 10.2 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein RuvB_N PF05496.7 KEG15332.1 - 0.007 15.4 0.1 0.85 8.6 0.0 2.9 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 KEG15332.1 - 0.0081 16.3 0.0 1.3 9.2 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_2 PF07724.9 KEG15332.1 - 0.0092 15.9 0.0 0.11 12.3 0.0 2.7 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) NB-ARC PF00931.17 KEG15332.1 - 0.011 14.6 0.1 0.89 8.3 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain Bac_DnaA PF00308.13 KEG15332.1 - 0.013 15.1 0.1 21 4.6 0.0 3.6 3 1 0 3 3 3 0 Bacterial dnaA protein NTPase_1 PF03266.10 KEG15332.1 - 0.02 14.6 0.4 1.9 8.2 0.0 3.0 3 0 0 3 3 3 0 NTPase Miro PF08477.8 KEG15332.1 - 0.023 15.2 0.8 2.9 8.3 0.0 3.7 3 1 0 3 3 2 0 Miro-like protein FtsK_SpoIIIE PF01580.13 KEG15332.1 - 0.023 14.1 0.0 0.24 10.8 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_11 PF13086.1 KEG15332.1 - 0.048 13.2 0.0 9.4 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 KEG15332.1 - 0.1 11.7 0.0 2.1 7.5 0.0 2.5 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Kinesin PF00225.18 KEG15332.1 - 0.12 11.0 0.0 2.7 6.6 0.0 2.6 3 0 0 3 3 3 0 Kinesin motor domain Pkinase PF00069.20 KEG15334.1 - 2.2e-63 213.8 0.0 3.3e-63 213.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG15334.1 - 1.2e-33 116.3 0.0 1.9e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Lipocalin_5 PF13924.1 KEG15334.1 - 1.9e-27 95.6 0.0 3.6e-27 94.7 0.0 1.5 1 0 0 1 1 1 1 Lipocalin-like domain PX PF00787.19 KEG15334.1 - 5.3e-13 48.7 0.3 1e-12 47.8 0.2 1.5 1 0 0 1 1 1 1 PX domain Kinase-like PF14531.1 KEG15334.1 - 7e-07 28.4 0.0 1.1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FYVE PF01363.16 KEG15334.1 - 0.002 17.9 9.8 0.002 17.9 6.8 1.8 2 0 0 2 2 2 1 FYVE zinc finger APH PF01636.18 KEG15334.1 - 0.037 13.7 0.2 0.13 12.0 0.1 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family zf-UDP PF14569.1 KEG15334.1 - 0.13 12.0 6.3 0.33 10.7 4.4 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_2 PF13923.1 KEG15334.1 - 0.22 11.5 9.0 0.63 10.1 6.2 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEG15334.1 - 6.7 6.4 10.6 16 5.2 7.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.20 KEG15336.1 - 1.5e-09 37.4 1.9 2.8e-09 36.5 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG15336.1 - 1.7e-07 30.6 0.0 3e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1183 PF06682.7 KEG15336.1 - 0.21 11.1 9.0 0.048 13.2 3.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) DUF3342 PF11822.3 KEG15339.1 - 2.4e-122 408.0 0.0 3.2e-122 407.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) TruD PF01142.13 KEG15340.1 - 6.5e-42 143.5 0.0 1.2e-39 136.0 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) PCNA_N PF00705.13 KEG15340.1 - 0.11 12.0 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, N-terminal domain Helicase_C_2 PF13307.1 KEG15342.1 - 1.5e-41 142.1 0.0 2.9e-41 141.2 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 KEG15342.1 - 1.8e-34 118.6 0.0 3.1e-34 117.8 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.24 KEG15342.1 - 0.00045 19.7 0.0 0.22 10.9 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 KEG15342.1 - 0.078 12.8 0.0 9.3 6.0 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Kelch_3 PF13415.1 KEG15343.1 - 6.3e-18 64.4 3.6 1.1e-05 25.4 0.0 4.1 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.1 KEG15343.1 - 1.1e-13 50.7 0.6 1.8e-07 30.9 0.0 4.3 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 KEG15343.1 - 5.4e-09 35.6 6.2 0.0021 17.8 0.0 3.9 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 KEG15343.1 - 7.8e-08 32.1 0.6 0.0046 17.0 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 KEG15343.1 - 0.00031 20.2 0.4 0.3 10.6 0.0 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 KEG15343.1 - 0.16 11.7 1.9 3.6 7.5 0.0 3.4 3 0 0 3 3 3 0 Kelch motif TPP_enzyme_N PF02776.13 KEG15344.1 - 7.3e-21 74.3 3.1 1.3e-20 73.5 0.1 2.4 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KEG15344.1 - 2.7e-11 43.2 6.3 3.1e-09 36.5 2.6 3.4 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain UbiA PF01040.13 KEG15345.1 - 6.1e-28 97.7 24.7 6.2e-28 97.7 16.5 1.5 1 1 0 1 1 1 1 UbiA prenyltransferase family LRR_6 PF13516.1 KEG15346.1 - 0.0095 15.9 0.4 6.3 7.1 0.1 3.8 4 0 0 4 4 4 2 Leucine Rich repeat Hydrolase_3 PF08282.7 KEG15347.1 - 1.2e-53 182.3 0.5 9.3e-38 130.2 0.0 2.0 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.8 KEG15347.1 - 7.5e-11 41.7 0.0 5.4e-05 22.6 0.0 2.7 2 1 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 KEG15347.1 - 4.5e-07 30.4 0.5 1.3e-05 25.7 0.4 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEG15347.1 - 0.0019 18.3 1.5 0.02 15.0 1.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 KEG15347.1 - 0.011 15.5 0.1 0.06 13.2 0.0 2.3 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 KEG15347.1 - 0.015 14.7 2.9 0.11 11.7 0.0 3.1 1 1 2 3 3 3 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Trehalose_PPase PF02358.11 KEG15347.1 - 0.015 14.2 0.0 0.63 8.9 0.0 2.1 2 0 0 2 2 2 0 Trehalose-phosphatase DUF460 PF04312.8 KEG15347.1 - 0.066 12.7 0.0 0.52 9.8 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF460) PALP PF00291.20 KEG15348.1 - 2.1e-39 135.5 0.0 2.6e-39 135.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ThiF PF00899.16 KEG15349.1 - 1.2e-07 31.6 0.1 1.6e-07 31.1 0.1 1.3 1 0 0 1 1 1 1 ThiF family HATPase_c_2 PF13581.1 KEG15349.1 - 0.081 12.7 0.1 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Saccharop_dh PF03435.13 KEG15350.1 - 1e-24 87.2 0.3 3.5e-24 85.4 0.1 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase Epimerase PF01370.16 KEG15350.1 - 3.8e-06 26.5 0.0 1.8e-05 24.3 0.0 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEG15350.1 - 7.1e-05 22.8 0.0 0.00017 21.6 0.0 1.7 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 KEG15350.1 - 0.00084 19.6 0.0 0.0031 17.7 0.0 2.0 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KEG15350.1 - 0.0044 15.7 0.0 0.012 14.3 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 KEG15350.1 - 0.0066 15.7 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 KEG15350.1 - 0.011 15.7 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.5 KEG15350.1 - 0.025 14.2 0.0 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 KR domain Peptidase_M8 PF01457.11 KEG15352.1 - 1.4e-80 271.1 0.0 5.6e-75 252.6 0.0 2.1 1 1 1 2 2 2 2 Leishmanolysin Mucin PF01456.12 KEG15352.1 - 0.0073 16.0 2.9 0.0073 16.0 2.0 1.9 2 0 0 2 2 2 1 Mucin-like glycoprotein dsDNA_bind PF01984.15 KEG15353.1 - 1e-23 83.3 10.9 1.3e-23 82.9 7.6 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain UPF0154 PF03672.8 KEG15353.1 - 0.37 10.4 2.7 2.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) DUF3492 PF11997.3 KEG15353.1 - 0.52 9.8 2.6 4.9 6.6 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3492) BCIP PF13862.1 KEG15354.1 - 1.9e-28 99.3 0.0 4e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 p21-C-terminal region-binding protein SGT1 PF07093.6 KEG15354.1 - 5.8 5.1 21.7 9.7 4.4 15.0 1.2 1 0 0 1 1 1 0 SGT1 protein DnaJ PF00226.26 KEG15355.1 - 2.8e-08 33.3 0.0 6.2e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain zf-ribbon_3 PF13248.1 KEG15355.1 - 0.072 12.3 4.1 0.87 8.8 0.3 2.7 2 0 0 2 2 2 0 zinc-ribbon domain SpoIIIAH PF12685.2 KEG15355.1 - 0.1 12.0 2.2 0.16 11.4 1.6 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein zf-RING_3 PF14369.1 KEG15355.1 - 0.3 11.1 2.9 11 6.1 0.2 2.7 2 0 0 2 2 2 0 zinc-finger CD99L2 PF12301.3 KEG15355.1 - 0.5 10.0 12.9 0.053 13.2 0.4 2.4 1 1 0 2 2 2 0 CD99 antigen like protein 2 zf-DHHC PF01529.15 KEG15356.1 - 5.3e-26 91.0 0.1 1.9e-25 89.2 0.0 1.9 1 1 1 2 2 2 1 DHHC palmitoyltransferase Adeno_E1A PF02703.9 KEG15356.1 - 0.2 11.0 1.5 0.34 10.3 1.1 1.3 1 0 0 1 1 1 0 Early E1A protein DUF663 PF04950.7 KEG15357.1 - 5.8e-74 248.7 0.0 5.8e-74 248.7 0.0 2.3 3 0 0 3 3 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KEG15357.1 - 5.6e-26 89.8 0.0 2e-25 88.1 0.0 2.0 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_16 PF13191.1 KEG15357.1 - 6.3e-05 23.0 0.3 0.00019 21.4 0.0 1.9 2 0 0 2 2 1 1 AAA ATPase domain GTP_EFTU PF00009.22 KEG15357.1 - 0.00021 20.8 0.0 0.0098 15.3 0.0 2.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KEG15357.1 - 0.00028 21.0 0.0 0.00072 19.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 KEG15357.1 - 0.00045 20.1 0.1 0.0015 18.4 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.9 KEG15357.1 - 0.0005 19.8 1.8 0.00063 19.4 0.0 2.1 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 KEG15357.1 - 0.0015 18.9 0.4 2.9 8.1 0.2 3.3 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.22 KEG15357.1 - 0.0017 18.6 0.0 0.014 15.7 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_10 PF12846.2 KEG15357.1 - 0.0037 16.7 0.4 0.008 15.6 0.0 1.7 2 0 0 2 2 2 1 AAA-like domain AAA_30 PF13604.1 KEG15357.1 - 0.0041 16.7 0.0 0.011 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KEG15357.1 - 0.0079 15.9 0.0 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KEG15357.1 - 0.01 15.6 1.5 0.018 14.8 0.0 2.2 2 0 0 2 2 1 0 AAA domain NTPase_1 PF03266.10 KEG15357.1 - 0.015 15.0 0.1 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 NTPase Miro PF08477.8 KEG15357.1 - 0.016 15.7 0.0 0.042 14.3 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AAA_17 PF13207.1 KEG15357.1 - 0.017 15.9 0.0 0.017 15.9 0.0 3.7 4 0 0 4 4 3 0 AAA domain DUF258 PF03193.11 KEG15357.1 - 0.017 14.2 0.0 0.034 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 KEG15357.1 - 0.019 14.5 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 KEG15357.1 - 0.02 14.5 0.9 0.037 13.7 0.0 1.9 2 0 0 2 2 1 0 Archaeal ATPase AAA PF00004.24 KEG15357.1 - 0.025 14.7 0.0 0.063 13.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KEG15357.1 - 0.026 14.2 0.1 0.079 12.7 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 KEG15357.1 - 0.053 13.1 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain ArgK PF03308.11 KEG15357.1 - 0.11 11.2 0.0 0.27 9.9 0.0 1.6 1 0 0 1 1 1 0 ArgK protein Methyltransf_16 PF10294.4 KEG15359.1 - 1.1e-14 54.2 0.0 3.5e-14 52.6 0.0 1.7 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KEG15359.1 - 0.012 16.1 0.3 0.057 13.9 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain DUF4586 PF15239.1 KEG15360.1 - 1.3e-32 113.5 0.1 1.7e-32 113.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) Kinesin PF00225.18 KEG15361.1 - 6.6e-84 281.4 0.0 1.5e-83 280.2 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Aldolase_II PF00596.16 KEG15362.1 - 1e-40 139.3 0.0 1.1e-40 139.1 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain SNF2_N PF00176.18 KEG15363.1 - 1.4e-43 148.7 0.0 2e-43 148.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEG15363.1 - 1.3e-07 31.3 0.0 2.8e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 KEG15363.1 - 4.2e-07 29.5 8.2 9.1e-07 28.4 5.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEG15363.1 - 6e-07 29.3 11.6 1.5e-06 28.1 8.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEG15363.1 - 3.2e-06 26.8 10.8 3.2e-06 26.8 7.5 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KEG15363.1 - 4.4e-06 26.3 9.8 9e-06 25.3 6.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KEG15363.1 - 9.9e-05 21.9 6.0 0.00023 20.8 4.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 KEG15363.1 - 0.00013 21.5 10.2 0.00034 20.1 7.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 KEG15363.1 - 0.0013 18.2 0.0 0.0023 17.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_6 PF14835.1 KEG15363.1 - 0.014 15.1 5.3 0.034 13.9 3.7 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 KEG15363.1 - 0.037 13.9 10.5 0.11 12.3 7.3 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Helicase_C_2 PF13307.1 KEG15363.1 - 0.038 13.9 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain zf-rbx1 PF12678.2 KEG15363.1 - 0.049 13.7 6.9 0.042 13.9 2.6 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger BUD22 PF09073.5 KEG15363.1 - 0.33 9.9 0.3 0.6 9.1 0.2 1.3 1 0 0 1 1 1 0 BUD22 DZR PF12773.2 KEG15363.1 - 0.69 9.7 4.0 1.6 8.5 2.7 1.6 1 0 0 1 1 1 0 Double zinc ribbon Rep_fac-A_C PF08646.5 KEG15364.1 - 3.3e-44 150.1 1.2 5.3e-41 139.7 0.1 3.1 3 0 0 3 3 3 1 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 KEG15364.1 - 1.4e-12 47.3 0.1 2.4e-10 40.1 0.0 2.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain DZR PF12773.2 KEG15364.1 - 0.02 14.6 1.5 0.04 13.7 1.0 1.4 1 0 0 1 1 1 0 Double zinc ribbon zinc-ribbons_6 PF07191.7 KEG15364.1 - 0.076 12.8 0.9 0.17 11.7 0.6 1.5 1 0 0 1 1 1 0 zinc-ribbons tRNA_anti_2 PF13742.1 KEG15364.1 - 0.097 12.5 0.0 0.45 10.4 0.0 2.0 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain Zn-ribbon_8 PF09723.5 KEG15364.1 - 1.7 8.6 5.5 40 4.2 0.1 3.3 3 0 0 3 3 3 0 Zinc ribbon domain DEAD PF00270.24 KEG15366.1 - 9.8e-25 86.9 0.0 1.2e-24 86.7 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KEG15366.1 - 4.4e-07 29.8 0.0 5.9e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SE PF00437.15 KEG15366.1 - 1.5e-05 24.0 0.0 2.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 KEG15366.1 - 0.0042 17.2 0.0 0.022 14.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEG15366.1 - 0.0059 16.3 0.1 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 KEG15366.1 - 0.0074 15.7 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 KEG15366.1 - 0.021 14.5 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B UvrD-helicase PF00580.16 KEG15366.1 - 0.026 13.8 0.0 0.038 13.3 0.0 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_16 PF13191.1 KEG15366.1 - 0.026 14.5 0.2 0.11 12.4 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain SNF2_N PF00176.18 KEG15366.1 - 0.039 12.7 0.0 0.05 12.3 0.0 1.1 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_10 PF12846.2 KEG15366.1 - 0.044 13.2 0.0 0.077 12.4 0.0 1.4 2 0 0 2 2 2 0 AAA-like domain Zeta_toxin PF06414.7 KEG15366.1 - 0.084 11.9 0.1 0.16 11.0 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.13 KEG15366.1 - 0.087 12.2 0.0 0.48 9.8 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family PhoH PF02562.11 KEG15366.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_23 PF13476.1 KEG15366.1 - 0.14 12.4 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Cyclase PF04199.8 KEG15367.1 - 2.7e-20 72.7 0.0 3.9e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase PI3_PI4_kinase PF00454.22 KEG15372.1 - 4.1e-39 134.4 0.5 8e-39 133.5 0.4 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 KEG15372.1 - 1.1e-15 57.4 7.5 3.9e-14 52.4 3.6 3.0 2 1 0 2 2 2 1 FAT domain FATC PF02260.15 KEG15372.1 - 4.7e-10 38.7 0.8 1.4e-09 37.1 0.5 1.9 1 0 0 1 1 1 1 FATC domain TPR_1 PF00515.23 KEG15372.1 - 0.022 14.3 1.2 1.5 8.5 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 KEG15372.1 - 0.42 10.3 10.0 3.6 7.3 0.1 4.6 4 0 0 4 4 4 0 TPR repeat MIP-T3 PF10243.4 KEG15373.1 - 3.8e-10 38.8 16.0 3.8e-10 38.8 11.1 2.3 1 1 0 2 2 2 1 Microtubule-binding protein MIP-T3 TruB_N PF01509.13 KEG15373.1 - 0.013 15.7 1.8 0.024 14.8 1.2 1.5 1 0 0 1 1 1 0 TruB family pseudouridylate synthase (N terminal domain) Kisspeptin PF15152.1 KEG15373.1 - 0.17 12.5 1.1 0.32 11.7 0.8 1.4 1 0 0 1 1 1 0 Kisspeptin BRF1 PF07741.8 KEG15373.1 - 1.9 8.7 7.9 6 7.1 5.5 1.9 1 1 0 1 1 1 0 Brf1-like TBP-binding domain Ndc1_Nup PF09531.5 KEG15373.1 - 3.4 5.9 7.7 4.2 5.6 5.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup rRNA_processing PF08524.6 KEG15375.1 - 8.9e-05 22.3 30.7 0.0011 18.7 20.5 2.4 1 1 1 2 2 2 1 rRNA processing DUF1788 PF08747.6 KEG15375.1 - 0.39 10.5 2.6 0.43 10.4 1.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1788) Peptidase_M41 PF01434.13 KEG15377.1 - 2.4e-52 177.5 0.6 4.3e-52 176.6 0.4 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KEG15377.1 - 2.7e-41 140.8 0.0 6.4e-41 139.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEG15377.1 - 0.00023 21.2 0.9 0.0025 17.8 0.1 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 KEG15377.1 - 0.0014 18.3 0.4 0.004 16.8 0.3 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KEG15377.1 - 0.0022 18.1 1.1 0.01 15.9 0.1 2.5 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 KEG15377.1 - 0.006 15.3 0.0 0.013 14.2 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus Zeta_toxin PF06414.7 KEG15377.1 - 0.0062 15.6 0.0 0.017 14.2 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin RuvB_N PF05496.7 KEG15377.1 - 0.0064 15.5 0.0 0.022 13.8 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 KEG15377.1 - 0.0087 15.4 3.5 0.026 13.9 0.2 2.7 2 1 1 3 3 3 1 AAA domain AAA_17 PF13207.1 KEG15377.1 - 0.011 16.5 0.1 0.036 14.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KEG15377.1 - 0.017 14.8 0.2 0.14 11.8 0.2 2.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KEG15377.1 - 0.022 14.1 0.1 0.049 13.0 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.21 KEG15377.1 - 0.025 14.0 0.1 0.14 11.6 0.0 2.3 2 1 0 2 2 1 0 Sigma-54 interaction domain NACHT PF05729.7 KEG15377.1 - 0.035 13.7 0.0 0.6 9.7 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.1 KEG15377.1 - 0.044 13.6 0.0 0.15 11.9 0.0 1.9 2 0 0 2 2 1 0 AAA domain DUF2075 PF09848.4 KEG15377.1 - 0.087 11.7 0.1 0.087 11.7 0.0 1.6 2 0 0 2 2 1 0 Uncharacterized conserved protein (DUF2075) AAA_2 PF07724.9 KEG15377.1 - 0.36 10.7 2.7 0.98 9.3 0.1 2.8 2 1 1 3 3 3 0 AAA domain (Cdc48 subfamily) Chromo PF00385.19 KEG15378.1 - 0.043 13.4 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain YqaJ PF09588.5 KEG15379.1 - 2.4e-42 144.4 0.0 3.6e-42 143.9 0.0 1.2 1 0 0 1 1 1 1 YqaJ-like viral recombinase domain zf-C3Hc3H PF13891.1 KEG15380.1 - 0.0077 16.2 0.5 3.1 7.9 0.0 2.4 2 0 0 2 2 2 2 Potential DNA-binding domain Methyltransf_18 PF12847.2 KEG15381.1 - 0.044 14.3 0.0 0.08 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 KEG15381.1 - 0.083 12.5 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KEG15381.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PSP1 PF04468.7 KEG15382.1 - 3.8e-27 94.1 0.1 6e-27 93.4 0.1 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region CLU PF13236.1 KEG15383.1 - 3.5e-21 75.6 0.0 5.1e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 KEG15383.1 - 2.8e-08 33.8 0.0 5.1e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 SchA_CurD PF04486.7 KEG15383.1 - 0.044 13.6 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 SchA/CurD like domain ArfGap PF01412.13 KEG15385.1 - 1.6e-40 137.5 0.0 2.2e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PMI_typeI PF01238.16 KEG15386.1 - 4.9e-84 282.4 0.0 9e-84 281.5 0.0 1.4 1 1 0 1 1 1 1 Phosphomannose isomerase type I PIF1 PF05970.9 KEG15387.1 - 1.1e-37 129.8 0.0 6.1e-30 104.3 0.0 3.1 3 0 0 3 3 3 2 PIF1-like helicase AAA_30 PF13604.1 KEG15387.1 - 4.7e-09 36.1 0.0 2.8e-08 33.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 KEG15387.1 - 2.3e-05 24.0 0.1 0.15 11.5 0.0 3.3 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 KEG15387.1 - 3.9e-05 23.7 0.0 0.0006 19.9 0.0 2.5 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 KEG15387.1 - 0.0002 21.0 0.3 0.00051 19.7 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KEG15387.1 - 0.00047 20.3 0.0 0.0018 18.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 KEG15387.1 - 0.0025 17.5 0.0 0.0053 16.4 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 KEG15387.1 - 0.0031 17.5 0.1 0.0073 16.3 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 KEG15387.1 - 0.0034 17.0 0.0 0.0082 15.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain ArgK PF03308.11 KEG15387.1 - 0.016 14.0 0.1 0.03 13.0 0.0 1.4 1 0 0 1 1 1 0 ArgK protein AAA_5 PF07728.9 KEG15387.1 - 0.022 14.4 0.1 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 KEG15387.1 - 0.054 12.4 0.0 0.15 11.0 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 KEG15387.1 - 0.08 12.3 0.3 0.15 11.4 0.2 1.4 1 0 0 1 1 1 0 AAA-like domain CbiA PF01656.18 KEG15387.1 - 0.12 11.7 0.1 0.24 10.7 0.1 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.10 KEG15387.1 - 0.14 11.8 0.8 0.27 10.9 0.0 1.8 2 0 0 2 2 2 0 NTPase DUF3720 PF12517.3 KEG15391.1 - 5.8 7.6 8.3 4.5 8.0 1.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3720) WD40 PF00400.27 KEG15393.1 - 1.6 8.6 4.5 42 4.2 0.0 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat DUF3767 PF12597.3 KEG15394.1 - 0.12 12.0 0.9 0.31 10.7 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) Mtc PF03820.12 KEG15394.1 - 0.34 9.5 0.8 9.7 4.7 0.0 2.1 2 0 0 2 2 2 0 Tricarboxylate carrier NAD_synthase PF02540.12 KEG15395.1 - 2.7e-36 124.7 0.0 3.8e-36 124.2 0.0 1.2 1 0 0 1 1 1 1 NAD synthase Toxin_67 PF15545.1 KEG15395.1 - 0.001 18.8 0.0 0.044 13.6 0.0 2.5 2 0 0 2 2 2 1 Putative toxin 67 Asn_synthase PF00733.16 KEG15395.1 - 0.08 12.4 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase PAPS_reduct PF01507.14 KEG15395.1 - 0.091 12.5 0.0 0.28 10.9 0.0 1.9 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family DNA_pol_E_B PF04042.11 KEG15397.1 - 7e-11 41.7 0.0 2.5e-10 39.9 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Coatomer_E PF04733.9 KEG15398.1 - 8.8e-35 120.2 1.2 3e-34 118.5 0.9 1.7 1 1 0 1 1 1 1 Coatomer epsilon subunit TPR_11 PF13414.1 KEG15398.1 - 4.4e-05 23.0 1.5 0.00063 19.3 0.0 3.3 3 1 1 4 4 4 1 TPR repeat TPR_19 PF14559.1 KEG15398.1 - 0.00046 20.4 15.2 0.18 12.1 0.4 4.0 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 KEG15398.1 - 0.00086 19.1 2.8 0.033 14.1 0.1 3.2 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEG15398.1 - 0.0072 16.8 16.4 0.073 13.7 0.5 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat VWA_3 PF13768.1 KEG15398.1 - 0.0092 15.6 2.1 0.02 14.5 0.3 2.5 2 1 0 2 2 2 1 von Willebrand factor type A domain TPR_2 PF07719.12 KEG15398.1 - 0.01 15.7 0.2 0.4 10.6 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat PPR_3 PF13812.1 KEG15398.1 - 0.22 11.9 2.2 33 5.1 0.1 3.6 3 1 0 3 3 3 0 Pentatricopeptide repeat domain TPR_16 PF13432.1 KEG15398.1 - 5.5 7.7 16.9 1.1 10.0 0.6 4.6 4 2 1 5 5 5 0 Tetratricopeptide repeat Mito_carr PF00153.22 KEG15399.1 - 4.4e-50 167.3 3.8 1.4e-17 63.2 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein PP2C PF00481.16 KEG15400.1 - 6e-72 242.0 0.0 8.4e-72 241.6 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KEG15400.1 - 0.0022 17.4 0.0 0.0045 16.4 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C MNE1 PF13762.1 KEG15400.1 - 0.16 12.0 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial splicing apparatus component MFS_1 PF07690.11 KEG15401.1 - 5e-25 87.9 21.3 7.3e-25 87.4 14.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Glycos_transf_2 PF00535.21 KEG15402.1 - 1.9e-05 24.4 0.0 2.7e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 TRADD_N PF09034.5 KEG15402.1 - 0.034 14.1 0.0 0.061 13.3 0.0 1.3 1 0 0 1 1 1 0 TRADD, N-terminal domain Kinesin PF00225.18 KEG15403.1 - 9.7e-72 241.4 0.0 4.9e-71 239.1 0.0 2.0 2 1 1 3 3 3 1 Kinesin motor domain Apc5 PF12862.2 KEG15403.1 - 0.25 11.2 2.3 0.7 9.7 1.6 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 V_ATPase_I PF01496.14 KEG15403.1 - 0.89 7.3 9.0 0.35 8.6 4.5 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 KEG15403.1 - 2.9 6.2 7.7 0.85 7.9 1.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) COG2 PF06148.6 KEG15403.1 - 4 7.2 11.0 0.11 12.4 1.0 2.8 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 HEAT_2 PF13646.1 KEG15404.1 - 6.1e-11 42.4 5.6 0.019 15.2 0.1 6.5 6 2 1 7 7 7 3 HEAT repeats HEAT_EZ PF13513.1 KEG15404.1 - 0.0011 19.3 2.2 1.5 9.3 0.0 4.9 4 1 1 5 5 5 1 HEAT-like repeat HEAT PF02985.17 KEG15404.1 - 0.0022 17.9 2.2 5 7.4 0.0 4.9 5 0 0 5 5 5 1 HEAT repeat Arm PF00514.18 KEG15404.1 - 0.021 14.6 3.8 44 4.1 0.1 4.5 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Acetyltransf_13 PF13880.1 KEG15405.1 - 1.8e-22 78.8 0.0 4e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_1 PF00583.19 KEG15405.1 - 0.0018 18.2 0.1 0.0061 16.5 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KEG15405.1 - 0.014 15.5 0.0 0.032 14.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-C3HC4_3 PF13920.1 KEG15407.1 - 0.0087 15.7 6.3 0.023 14.3 4.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEG15407.1 - 0.012 15.6 5.0 0.012 15.6 3.5 2.0 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) LRR_4 PF12799.2 KEG15409.1 - 1.2e-14 53.4 9.4 7.7e-06 25.4 0.0 5.3 3 1 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG15409.1 - 9.4e-11 41.3 13.0 3.4e-05 23.4 0.4 3.9 3 1 1 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 KEG15409.1 - 6.1e-09 34.7 14.6 0.81 9.9 0.2 7.4 8 1 0 8 8 8 4 Leucine Rich Repeat LRR_7 PF13504.1 KEG15409.1 - 2.9e-05 23.5 21.0 0.1 12.8 0.1 7.5 8 0 0 8 8 8 3 Leucine rich repeat LRR_6 PF13516.1 KEG15409.1 - 0.00045 19.9 6.4 27 5.2 0.0 6.3 6 1 0 6 6 6 0 Leucine Rich repeat LRR_9 PF14580.1 KEG15409.1 - 0.021 14.3 1.2 0.34 10.4 0.1 2.8 2 2 0 2 2 2 0 Leucine-rich repeat Rsc14 PF08586.5 KEG15409.1 - 0.21 12.1 1.1 1.1 9.7 0.1 2.6 3 0 0 3 3 3 0 RSC complex, Rsc14/Ldb7 subunit 14-3-3 PF00244.15 KEG15410.1 - 0.024 13.7 0.0 0.027 13.5 0.0 1.1 1 0 0 1 1 1 0 14-3-3 protein LRR_6 PF13516.1 KEG15411.1 - 9.9e-08 31.2 0.2 1.8 8.8 0.0 5.2 5 0 0 5 5 5 3 Leucine Rich repeat LRR_7 PF13504.1 KEG15411.1 - 0.0062 16.5 1.8 1.7e+02 3.1 0.0 5.5 5 0 0 5 5 5 0 Leucine rich repeat ZZ PF00569.12 KEG15412.1 - 2.4e-08 33.3 23.3 2.7e-07 29.9 5.7 2.5 2 0 0 2 2 2 2 Zinc finger, ZZ type Arena_RNA_pol PF06317.6 KEG15412.1 - 0.0072 12.9 0.0 0.01 12.4 0.0 1.1 1 0 0 1 1 1 1 Arenavirus RNA polymerase BCDHK_Adom3 PF10436.4 KEG15413.1 - 1.5e-29 102.6 0.2 2.3e-29 102.0 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KEG15413.1 - 1.4e-13 50.5 0.0 1.1e-12 47.5 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KEG15413.1 - 0.0001 21.9 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Enkurin PF13864.1 KEG15414.1 - 4.5e-24 84.5 5.9 9e-24 83.5 4.1 1.5 1 0 0 1 1 1 1 Calmodulin-binding Ribophorin_II PF05817.9 KEG15414.1 - 0.12 10.5 0.2 0.16 10.1 0.1 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II AAA_5 PF07728.9 KEG15416.1 - 2.7e-128 422.4 0.0 1e-23 83.5 0.0 7.7 7 0 0 7 7 7 7 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KEG15416.1 - 1.1e-32 112.3 0.0 1.4e-07 31.1 0.0 7.4 7 0 0 7 7 7 4 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 KEG15416.1 - 1.2e-23 83.7 0.1 0.00089 19.4 0.0 7.5 7 0 0 7 7 7 5 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEG15416.1 - 4.7e-23 81.7 0.0 0.0044 17.1 0.0 7.2 6 0 0 6 6 6 5 AAA domain AAA_16 PF13191.1 KEG15416.1 - 2.3e-21 76.6 21.7 3.6e-06 27.0 0.0 9.3 9 0 0 9 9 7 5 AAA ATPase domain Sigma54_activ_2 PF14532.1 KEG15416.1 - 5e-20 71.9 0.0 0.00084 19.3 0.0 7.0 6 0 0 6 6 6 4 Sigma-54 interaction domain AAA_14 PF13173.1 KEG15416.1 - 5.8e-20 71.4 0.0 0.00052 19.9 0.0 6.9 6 0 0 6 6 6 4 AAA domain Sigma54_activat PF00158.21 KEG15416.1 - 1.1e-18 67.3 0.0 0.00086 18.8 0.0 6.7 6 1 0 6 6 6 3 Sigma-54 interaction domain AAA_17 PF13207.1 KEG15416.1 - 6.3e-16 59.2 0.6 0.23 12.3 0.0 7.7 7 0 0 7 7 6 3 AAA domain ABC_tran PF00005.22 KEG15416.1 - 8.7e-15 55.2 0.1 0.042 14.1 0.0 7.1 6 0 0 6 6 6 2 ABC transporter AAA_33 PF13671.1 KEG15416.1 - 2.7e-13 50.0 0.0 0.042 13.7 0.0 7.8 7 0 0 7 7 7 3 AAA domain UPF0079 PF02367.12 KEG15416.1 - 2.1e-12 46.7 3.1 0.016 14.8 0.1 6.4 6 0 0 6 6 6 2 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 KEG15416.1 - 2.7e-12 46.2 2.0 0.13 11.9 0.0 6.7 6 0 0 6 6 6 2 Part of AAA domain AAA_29 PF13555.1 KEG15416.1 - 3.3e-12 45.7 0.2 1.3 8.6 0.0 6.9 6 0 0 6 6 6 2 P-loop containing region of AAA domain IstB_IS21 PF01695.12 KEG15416.1 - 5.6e-12 45.4 0.1 0.019 14.4 0.0 5.0 4 0 0 4 4 4 3 IstB-like ATP binding protein Mg_chelatase PF01078.16 KEG15416.1 - 1.3e-11 44.0 0.3 0.34 10.0 0.0 8.2 8 0 0 8 8 8 2 Magnesium chelatase, subunit ChlI DUF258 PF03193.11 KEG15416.1 - 4.9e-11 42.0 0.6 0.72 9.0 0.1 6.4 6 0 0 6 6 6 3 Protein of unknown function, DUF258 AAA_18 PF13238.1 KEG15416.1 - 1.3e-10 41.6 0.0 0.3 11.4 0.0 7.1 6 0 0 6 6 6 2 AAA domain T2SE PF00437.15 KEG15416.1 - 4.4e-10 38.9 0.4 0.13 11.1 0.0 6.4 6 0 0 6 6 6 1 Type II/IV secretion system protein RNA_helicase PF00910.17 KEG15416.1 - 1.3e-09 38.1 0.3 0.13 12.4 0.0 6.8 7 0 0 7 7 6 1 RNA helicase AAA_25 PF13481.1 KEG15416.1 - 1e-07 31.5 0.6 0.97 8.8 0.0 6.4 6 0 0 6 6 6 1 AAA domain DUF815 PF05673.8 KEG15416.1 - 4.2e-07 29.1 3.5 1.4 7.7 0.0 5.9 7 0 0 7 7 7 2 Protein of unknown function (DUF815) NACHT PF05729.7 KEG15416.1 - 7.5e-07 28.9 3.4 0.17 11.5 0.0 5.9 6 0 0 6 6 6 2 NACHT domain AAA_10 PF12846.2 KEG15416.1 - 1.9e-05 24.2 2.9 1.2 8.5 0.0 5.1 5 0 0 5 5 5 1 AAA-like domain CPT PF07931.7 KEG15416.1 - 9.8e-05 22.0 1.0 0.29 10.7 0.0 5.2 5 1 0 5 5 4 1 Chloramphenicol phosphotransferase-like protein KaiC PF06745.8 KEG15416.1 - 0.00023 20.3 0.3 1.8 7.6 0.0 4.8 5 0 0 5 5 5 1 KaiC Miro PF08477.8 KEG15416.1 - 0.00035 21.0 1.1 30 5.1 0.0 5.3 5 0 0 5 5 4 0 Miro-like protein PhoH PF02562.11 KEG15416.1 - 0.00088 18.5 5.9 5.5 6.1 0.0 5.3 5 0 0 5 5 5 0 PhoH-like protein PIF1 PF05970.9 KEG15416.1 - 0.0012 17.8 1.1 2.9 6.7 0.0 5.2 6 0 0 6 6 6 1 PIF1-like helicase MMR_HSR1 PF01926.18 KEG15416.1 - 0.0014 18.5 0.0 33 4.4 0.0 4.9 4 0 0 4 4 4 0 50S ribosome-binding GTPase TIP49 PF06068.8 KEG15416.1 - 0.0016 17.2 2.7 2.5 6.6 0.0 4.2 5 0 0 5 5 5 1 TIP49 C-terminus DEAD PF00270.24 KEG15416.1 - 0.0019 17.7 0.0 3 7.3 0.0 4.9 5 0 0 5 5 4 1 DEAD/DEAH box helicase NTPase_1 PF03266.10 KEG15416.1 - 0.0026 17.4 2.3 3.5 7.3 0.0 4.5 4 0 0 4 4 4 1 NTPase AAA_6 PF12774.2 KEG15416.1 - 0.0041 16.6 0.0 6.8 6.1 0.0 4.6 6 0 0 6 6 5 0 Hydrolytic ATP binding site of dynein motor region D1 ArgK PF03308.11 KEG15416.1 - 0.011 14.4 0.6 1.4 7.6 0.1 2.8 2 0 0 2 2 2 0 ArgK protein PduV-EutP PF10662.4 KEG15416.1 - 0.016 14.7 2.1 7.9 5.9 0.1 4.6 6 0 0 6 6 5 0 Ethanolamine utilisation - propanediol utilisation KAP_NTPase PF07693.9 KEG15416.1 - 0.024 13.6 0.0 3.9 6.3 0.0 3.7 5 0 0 5 5 4 0 KAP family P-loop domain ATP-synt_ab PF00006.20 KEG15416.1 - 0.031 13.7 0.0 11 5.4 0.0 3.2 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain Rad17 PF03215.10 KEG15416.1 - 0.1 11.2 0.0 22 3.5 0.0 3.9 5 0 0 5 5 5 0 Rad17 cell cycle checkpoint protein DS PF01916.12 KEG15417.1 - 5.6e-77 258.7 0.0 9.6e-77 258.0 0.0 1.3 1 1 0 1 1 1 1 Deoxyhypusine synthase DUF948 PF06103.6 KEG15419.1 - 0.00044 20.0 0.0 0.00094 19.0 0.0 1.5 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.4 KEG15419.1 - 0.006 16.6 0.0 0.044 13.9 0.0 1.9 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_32 PF13654.1 KEG15419.1 - 0.032 12.9 0.1 0.039 12.6 0.0 1.0 1 0 0 1 1 1 0 AAA domain Serine_rich PF08824.5 KEG15419.1 - 0.087 12.5 0.2 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Serine rich protein interaction domain TBPIP PF07106.8 KEG15419.1 - 0.094 12.2 0.1 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Apolipoprotein PF01442.13 KEG15419.1 - 0.1 12.1 0.5 8.1 5.8 0.0 2.0 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain EcKinase PF02958.15 KEG15419.1 - 0.13 11.4 0.1 0.16 11.0 0.1 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase Hpt PF01627.18 KEG15419.1 - 0.2 11.6 3.1 1.8 8.6 0.3 2.4 2 0 0 2 2 2 0 Hpt domain Kelch_6 PF13964.1 KEG15422.1 - 9.8e-31 104.6 12.3 5.1e-06 26.4 0.0 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.1 KEG15422.1 - 3.3e-25 87.5 19.4 3.1e-06 27.1 0.0 7.0 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.1 KEG15422.1 - 6e-25 86.7 19.7 2e-08 33.9 0.3 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_4 PF13418.1 KEG15422.1 - 1.2e-22 79.3 12.7 3.1e-05 23.6 0.0 6.0 5 1 0 5 5 5 5 Galactose oxidase, central domain Kelch_1 PF01344.20 KEG15422.1 - 3e-21 74.7 20.2 3.4e-06 26.5 0.0 6.9 7 1 0 7 7 7 4 Kelch motif Kelch_2 PF07646.10 KEG15422.1 - 2.4e-17 61.9 14.6 0.001 18.7 0.2 7.0 7 1 0 7 7 7 5 Kelch motif PQQ_3 PF13570.1 KEG15422.1 - 0.098 12.9 3.0 3.2 8.1 0.1 3.6 4 0 0 4 4 4 0 PQQ-like domain Myb_DNA-binding PF00249.26 KEG15425.1 - 0.036 14.1 0.9 41 4.3 0.1 3.7 3 0 0 3 3 3 0 Myb-like DNA-binding domain E3_UbLigase_R4 PF13764.1 KEG15425.1 - 0.04 11.8 0.0 0.059 11.2 0.0 1.1 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 Nop16 PF09420.5 KEG15425.1 - 0.066 13.3 0.0 4.5 7.3 0.0 3.0 2 1 1 3 3 3 0 Ribosome biogenesis protein Nop16 LRR_4 PF12799.2 KEG15426.1 - 0.0035 16.9 0.1 0.19 11.3 0.0 2.9 2 1 1 3 3 3 1 Leucine Rich repeats (2 copies) DUF812 PF05667.6 KEG15427.1 - 0.066 11.7 16.3 0.093 11.2 11.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) CAF-1_p150 PF11600.3 KEG15427.1 - 1.1 8.6 17.3 0.018 14.4 6.3 2.0 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal V_ATPase_I PF01496.14 KEG15427.1 - 2.1 6.0 6.6 3.4 5.3 4.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GAS PF13851.1 KEG15427.1 - 4.5 6.4 19.6 0.36 9.9 10.1 1.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1736 PF08409.6 KEG15428.1 - 8.7e-16 57.2 0.1 3e-15 55.5 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_11 PF13414.1 KEG15428.1 - 0.0074 15.9 0.1 5.6 6.6 0.2 2.7 2 0 0 2 2 2 2 TPR repeat TPR_17 PF13431.1 KEG15428.1 - 0.081 13.1 0.2 5.9 7.3 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat SpoU_methylas_C PF12105.3 KEG15429.1 - 0.15 11.6 0.3 19 4.8 0.0 3.1 3 0 0 3 3 3 0 SpoU, rRNA methylase, C-terminal MORN PF02493.15 KEG15430.1 - 2.7e-06 26.7 15.4 0.00071 19.1 0.0 6.1 6 1 0 6 6 6 2 MORN repeat Kelch_3 PF13415.1 KEG15431.1 - 1e-15 57.3 8.6 0.0014 18.7 0.0 5.4 4 1 0 4 4 4 4 Galactose oxidase, central domain Kelch_6 PF13964.1 KEG15431.1 - 7.2e-14 51.2 4.4 0.00014 21.8 0.0 4.3 2 2 2 4 4 4 3 Kelch motif Kelch_5 PF13854.1 KEG15431.1 - 2.7e-11 43.1 6.1 0.0003 20.6 0.2 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 KEG15431.1 - 1.9e-09 36.8 8.1 4.2e-06 26.2 0.0 3.9 4 1 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 KEG15431.1 - 3.4e-09 36.0 2.2 0.0046 16.6 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 KEG15431.1 - 2.2e-07 30.5 12.6 0.001 18.8 0.5 5.9 4 2 1 5 5 5 2 Galactose oxidase, central domain Ribosomal_L7Ae PF01248.21 KEG15432.1 - 1e-17 63.3 0.1 1.3e-17 63.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family VirionAssem_T7 PF11653.3 KEG15432.1 - 0.011 16.5 0.6 0.017 15.8 0.4 1.3 1 0 0 1 1 1 0 Bacteriophage T7 virion assembly protein Rgp1 PF08737.5 KEG15433.1 - 6.2e-26 91.4 0.2 4.5e-12 45.7 0.0 3.0 3 0 0 3 3 3 2 Rgp1 Arrestin_C PF02752.17 KEG15433.1 - 0.15 12.1 0.0 27 4.8 0.0 2.6 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Peptidase_C78 PF07910.8 KEG15434.1 - 2.9e-51 173.6 0.0 4.1e-51 173.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 DUF445 PF04286.7 KEG15436.1 - 0.11 11.9 0.4 0.16 11.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Prenyltrans PF00432.16 KEG15437.1 - 1.7e-61 203.3 21.1 8.4e-13 47.6 0.1 6.0 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KEG15437.1 - 1.8e-45 153.9 3.9 1.2e-17 64.2 0.0 4.0 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 KEG15437.1 - 3.3e-13 49.5 0.1 2.8e-07 30.4 0.0 3.4 1 1 2 3 3 3 2 Prenyltransferase-like A2M_comp PF07678.9 KEG15437.1 - 0.086 12.0 1.1 25 4.0 0.0 3.5 2 1 0 4 4 4 0 A-macroglobulin complement component RPA_interact_N PF14766.1 KEG15438.1 - 0.047 13.1 0.5 0.13 11.7 0.4 1.8 1 0 0 1 1 1 0 Replication protein A interacting N-terminal DUF561 PF04481.7 KEG15438.1 - 0.077 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF561) GAF_2 PF13185.1 KEG15439.1 - 0.00022 21.7 0.0 0.0005 20.5 0.0 1.6 1 0 0 1 1 1 1 GAF domain Glyoxalase_4 PF13669.1 KEG15439.1 - 0.11 12.4 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Lsr2 PF11774.3 KEG15439.1 - 0.16 11.9 5.7 12 5.8 0.0 2.6 2 0 0 2 2 2 0 Lsr2 UCH PF00443.24 KEG15440.1 - 3.2e-44 151.0 0.0 5.8e-44 150.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEG15440.1 - 3.3e-19 69.4 0.0 1.2e-18 67.6 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Arch_fla_DE PF04659.8 KEG15440.1 - 0.059 13.1 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Archaeal flagella protein Plasmid_killer PF05015.8 KEG15441.1 - 0.1 12.7 0.7 0.68 10.1 0.6 2.1 2 0 0 2 2 2 0 Plasmid maintenance system killer protein DnaJ PF00226.26 KEG15442.1 - 1.6e-09 37.3 0.1 3e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain GRIP PF01465.15 KEG15443.1 - 4.7e-14 51.6 0.0 8.9e-14 50.7 0.0 1.5 1 0 0 1 1 1 1 GRIP domain Tup_N PF08581.5 KEG15443.1 - 0.00044 20.3 8.5 0.036 14.2 0.8 3.8 3 0 0 3 3 3 2 Tup N-terminal DivIC PF04977.10 KEG15443.1 - 0.01 15.2 19.3 1.7 8.1 0.0 5.8 3 1 3 6 6 6 0 Septum formation initiator Reo_sigmaC PF04582.7 KEG15443.1 - 0.037 13.2 5.2 0.059 12.5 1.8 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein ENOD93 PF03386.9 KEG15443.1 - 0.078 12.6 0.2 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Early nodulin 93 ENOD93 protein HALZ PF02183.13 KEG15443.1 - 0.1 12.3 0.2 0.1 12.3 0.1 5.4 6 0 0 6 6 6 0 Homeobox associated leucine zipper AAA_13 PF13166.1 KEG15443.1 - 0.67 8.3 11.3 22 3.3 8.0 2.4 1 1 0 1 1 1 0 AAA domain Bacillus_HBL PF05791.6 KEG15443.1 - 1.1 8.5 6.0 4.4 6.6 0.0 4.0 4 1 0 5 5 5 0 Bacillus haemolytic enterotoxin (HBL) DUF4407 PF14362.1 KEG15443.1 - 1.6 7.6 16.9 0.13 11.2 0.4 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) DUF972 PF06156.8 KEG15443.1 - 1.6 9.1 17.6 1.8 8.9 0.1 5.1 3 2 1 4 4 4 0 Protein of unknown function (DUF972) Atg14 PF10186.4 KEG15443.1 - 1.8 7.4 18.4 0.93 8.3 0.1 3.7 2 1 1 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Nsp1_C PF05064.8 KEG15443.1 - 2.5 7.7 9.0 1.1 8.9 1.1 3.5 2 1 1 3 3 3 0 Nsp1-like C-terminal region TBPIP PF07106.8 KEG15443.1 - 3.5 7.1 16.5 10 5.6 0.1 4.6 4 1 1 5 5 5 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1664 PF07889.7 KEG15443.1 - 3.8 7.3 14.6 3.4 7.4 0.8 4.0 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.5 KEG15443.1 - 5.1 7.1 14.3 0.18 11.9 0.9 3.6 4 1 1 5 5 3 0 Fibrinogen alpha/beta chain family Spc24 PF08286.6 KEG15443.1 - 9.8 5.9 21.9 13 5.5 3.4 5.6 5 2 0 5 5 5 0 Spc24 subunit of Ndc80 Spc7 PF08317.6 KEG15444.1 - 0.042 12.5 1.0 0.059 12.0 0.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein HALZ PF02183.13 KEG15444.1 - 1.3 8.7 5.9 0.53 10.0 2.1 1.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper TPR_12 PF13424.1 KEG15445.1 - 0.014 15.2 3.0 5.6 6.9 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3856 PF12968.2 KEG15445.1 - 0.072 12.9 0.0 0.59 9.9 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) PX PF00787.19 KEG15446.1 - 3.6e-10 39.6 0.2 1.1e-09 38.0 0.1 1.9 1 0 0 1 1 1 1 PX domain Abhydrolase_6 PF12697.2 KEG15447.1 - 3.8e-05 23.6 0.0 7.6e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1620 PF07774.8 KEG15448.1 - 4.2e-47 160.1 0.0 1.1e-46 158.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 KEG15448.1 - 1.5e-09 37.7 0.5 1.5e-09 37.7 0.4 3.7 3 1 2 5 5 5 1 PQQ-like domain PQQ PF01011.16 KEG15448.1 - 2.5e-06 26.7 0.0 0.12 11.9 0.0 3.7 3 0 0 3 3 3 2 PQQ enzyme repeat PQQ_3 PF13570.1 KEG15448.1 - 0.045 14.0 5.4 9.9 6.5 0.0 5.1 5 0 0 5 5 5 0 PQQ-like domain Utp8 PF10395.4 KEG15448.1 - 0.09 11.0 0.1 1.3 7.2 0.0 2.0 2 0 0 2 2 2 0 Utp8 family DUF1936 PF09151.5 KEG15448.1 - 0.41 10.1 3.7 0.47 9.9 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) Rep_fac-A_C PF08646.5 KEG15450.1 - 0.00013 21.6 0.0 0.00028 20.5 0.0 1.5 1 0 0 1 1 1 1 Replication factor-A C terminal domain Rep-A_N PF04057.7 KEG15450.1 - 0.0022 17.7 0.0 0.0097 15.6 0.0 2.0 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain Bestrophin PF01062.16 KEG15450.1 - 0.02 13.8 0.1 0.03 13.2 0.0 1.2 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel DHC_N2 PF08393.8 KEG15451.1 - 4.1e-117 391.1 0.0 4.1e-117 391.1 0.0 5.3 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 KEG15451.1 - 4.9e-116 388.4 1.1 9.9e-116 387.4 0.0 2.0 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 KEG15451.1 - 3.1e-83 278.8 0.1 1.8e-82 276.3 0.0 2.3 3 0 0 3 3 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_5 PF07728.9 KEG15451.1 - 2.5e-36 124.4 0.1 5.9e-21 74.6 0.0 5.9 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_8 PF12780.2 KEG15451.1 - 7.4e-34 116.9 0.5 1.1e-29 103.2 0.0 3.6 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 MT PF12777.2 KEG15451.1 - 5.5e-32 110.8 15.4 2.4e-31 108.7 9.3 2.4 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor DHC_N1 PF08385.7 KEG15451.1 - 3.6e-30 104.9 0.2 3.6e-30 104.9 0.1 5.0 6 1 1 7 7 5 1 Dynein heavy chain, N-terminal region 1 AAA_9 PF12781.2 KEG15451.1 - 3.7e-29 101.1 0.1 3.7e-29 101.1 0.1 2.0 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_7 PF12775.2 KEG15451.1 - 6.3e-23 81.2 0.7 2.5e-22 79.2 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_16 PF13191.1 KEG15451.1 - 5.4e-14 52.6 0.0 0.0022 18.0 0.0 5.5 4 0 0 4 4 4 3 AAA ATPase domain AAA PF00004.24 KEG15451.1 - 7.7e-13 48.7 0.2 0.038 14.1 0.0 5.6 5 0 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEG15451.1 - 2.5e-09 37.3 0.0 0.02 15.0 0.0 4.8 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 KEG15451.1 - 2e-07 31.8 0.0 0.0088 16.8 0.0 5.1 4 0 0 4 4 3 1 AAA domain AAA_28 PF13521.1 KEG15451.1 - 1.3e-06 28.4 0.0 0.34 10.8 0.0 4.3 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.1 KEG15451.1 - 1.5e-06 27.9 1.1 0.097 12.2 0.0 4.4 5 0 0 5 5 5 1 AAA domain AAA_33 PF13671.1 KEG15451.1 - 4.2e-06 26.7 0.0 0.075 12.9 0.0 3.8 3 0 0 3 3 3 2 AAA domain AAA_14 PF13173.1 KEG15451.1 - 8.1e-06 25.7 0.0 0.047 13.5 0.0 4.4 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 KEG15451.1 - 1.1e-05 24.6 0.0 0.0064 15.6 0.0 3.6 3 0 0 3 3 3 1 Protein of unknown function, DUF258 RNA_helicase PF00910.17 KEG15451.1 - 1.3e-05 25.3 0.0 3.9 7.7 0.0 3.8 3 0 0 3 3 3 0 RNA helicase Zeta_toxin PF06414.7 KEG15451.1 - 9.2e-05 21.6 0.1 0.089 11.8 0.0 3.8 3 0 0 3 3 3 1 Zeta toxin NACHT PF05729.7 KEG15451.1 - 0.00014 21.5 4.1 0.029 14.0 0.0 3.5 4 0 0 4 4 2 2 NACHT domain AAA_19 PF13245.1 KEG15451.1 - 0.0002 21.0 0.6 1 9.1 0.0 4.4 4 0 0 4 4 3 1 Part of AAA domain AAA_25 PF13481.1 KEG15451.1 - 0.00034 20.0 0.7 0.3 10.4 0.0 4.0 4 0 0 4 4 3 1 AAA domain ABC_tran PF00005.22 KEG15451.1 - 0.0007 19.9 10.9 0.019 15.2 0.0 4.7 5 0 0 5 5 3 2 ABC transporter UPF0079 PF02367.12 KEG15451.1 - 0.0017 18.0 0.1 0.88 9.2 0.0 3.5 3 0 0 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 KEG15451.1 - 0.0029 17.3 15.3 0.029 14.0 0.0 5.0 5 0 0 5 5 3 2 Archaeal ATPase AAA_23 PF13476.1 KEG15451.1 - 0.0031 17.8 34.4 10 6.4 0.0 7.2 6 0 0 6 6 6 0 AAA domain AAA_18 PF13238.1 KEG15451.1 - 0.0037 17.5 3.7 0.31 11.3 0.0 5.4 5 0 0 5 5 3 1 AAA domain MobB PF03205.9 KEG15451.1 - 0.0086 15.7 2.1 0.91 9.2 0.0 3.6 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 KEG15451.1 - 0.013 15.0 0.4 21 4.5 0.0 4.2 4 0 0 4 4 4 0 FtsK/SpoIIIE family AAA_29 PF13555.1 KEG15451.1 - 0.014 14.8 0.0 0.18 11.3 0.0 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_24 PF13479.1 KEG15451.1 - 0.016 14.7 0.2 35 3.8 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_21 PF13304.1 KEG15451.1 - 0.025 14.5 0.0 0.12 12.2 0.0 2.3 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 KEG15451.1 - 0.027 13.9 0.2 4.7 6.6 0.0 3.6 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.16 KEG15451.1 - 0.034 13.3 0.1 4.4 6.4 0.0 2.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI cobW PF02492.14 KEG15451.1 - 0.087 12.2 3.4 6.5 6.1 0.1 3.2 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Guanylate_kin PF00625.16 KEG15451.1 - 0.093 12.1 8.2 0.57 9.5 0.0 4.3 4 0 0 4 4 3 0 Guanylate kinase ATP-synt_ab PF00006.20 KEG15451.1 - 0.096 12.1 0.1 0.32 10.4 0.0 1.9 2 0 0 2 2 1 0 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.18 KEG15451.1 - 0.18 11.7 0.0 15 5.5 0.0 3.2 3 0 0 3 3 2 0 50S ribosome-binding GTPase zf-CCHC_3 PF13917.1 KEG15452.1 - 1.6e-16 59.7 0.7 1.6e-16 59.7 0.5 1.6 2 0 0 2 2 2 1 Zinc knuckle eIF3g PF12353.3 KEG15452.1 - 0.033 14.0 0.4 0.033 14.0 0.3 2.2 2 1 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G DUF1193 PF06702.7 KEG15453.1 - 1.5e-06 27.8 0.0 2.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1193) Metallophos PF00149.23 KEG15454.1 - 1.7e-35 122.2 0.0 4.5e-24 84.9 0.0 2.2 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KEG15454.1 - 0.0076 16.1 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Opiods_neuropep PF01160.13 KEG15454.1 - 0.18 11.5 8.0 3.6 7.4 0.7 2.5 2 0 0 2 2 2 0 Vertebrate endogenous opioids neuropeptide Amastin PF07344.6 KEG15454.1 - 0.99 9.0 6.8 1 8.9 0.7 2.8 2 1 1 3 3 3 0 Amastin surface glycoprotein FHA PF00498.21 KEG15458.1 - 2.7e-07 30.5 0.0 5.3e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 FHA domain BRCT PF00533.21 KEG15458.1 - 4.4e-06 26.7 0.0 0.071 13.2 0.0 2.5 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KEG15458.1 - 0.029 14.2 0.0 0.065 13.0 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain DUF3619 PF12279.3 KEG15459.1 - 0.044 13.8 3.4 0.13 12.3 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3619) Kinesin PF00225.18 KEG15460.1 - 1.3e-106 356.1 0.4 2.2e-106 355.3 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain Pex24p PF06398.6 KEG15460.1 - 6.7e-08 31.7 0.5 1.2e-07 30.8 0.3 1.4 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin GTP_EFTU PF00009.22 KEG15460.1 - 0.064 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF3573 PF12097.3 KEG15460.1 - 0.084 11.4 4.6 0.11 11.0 2.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) Herpes_UL6 PF01763.11 KEG15460.1 - 0.15 10.1 6.5 0.16 10.0 3.7 1.4 1 1 0 1 1 1 0 Herpesvirus UL6 like DUF2937 PF11157.3 KEG15460.1 - 0.25 10.6 2.0 0.53 9.6 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) COG5 PF10392.4 KEG15460.1 - 0.26 11.2 10.5 0.1 12.5 0.4 2.4 1 1 1 2 2 2 0 Golgi transport complex subunit 5 AAA_13 PF13166.1 KEG15460.1 - 0.29 9.5 11.5 0.55 8.6 8.0 1.4 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.4 KEG15460.1 - 3.5 6.4 19.8 0.41 9.5 9.6 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Cullin_binding PF03556.10 KEG15461.1 - 2.4e-20 72.8 2.1 3.4e-20 72.3 1.5 1.2 1 0 0 1 1 1 1 Cullin binding LRR_4 PF12799.2 KEG15462.1 - 1.3e-17 63.0 8.0 5.5e-09 35.4 1.2 3.5 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG15462.1 - 1.5e-10 40.6 12.3 7e-06 25.7 1.6 2.8 3 0 0 3 3 3 2 Leucine rich repeat LRR_9 PF14580.1 KEG15462.1 - 3.7e-10 39.6 0.7 1.4e-09 37.7 0.3 2.0 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.28 KEG15462.1 - 1.1e-06 27.8 8.5 0.42 10.8 0.1 5.4 4 1 0 4 4 4 3 Leucine Rich Repeat LRR_7 PF13504.1 KEG15462.1 - 1.8e-05 24.2 5.9 11 6.7 0.1 5.8 5 1 1 6 6 6 3 Leucine rich repeat LRR_6 PF13516.1 KEG15462.1 - 0.0036 17.2 14.3 0.045 13.8 0.1 4.6 5 0 0 5 5 5 2 Leucine Rich repeat Cyclin PF08613.6 KEG15463.1 - 2.9e-22 79.6 0.3 5.2e-22 78.8 0.2 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KEG15463.1 - 1.7e-07 30.8 0.0 3.4e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF773 PF05600.7 KEG15465.1 - 2.5e-13 49.6 7.8 9.4e-07 27.9 3.0 3.5 1 1 2 3 3 3 3 Protein of unknown function (DUF773) SAM_2 PF07647.12 KEG15465.1 - 0.049 13.4 0.2 0.22 11.4 0.0 2.1 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) AMMECR1 PF01871.12 KEG15465.1 - 0.068 12.2 0.2 0.12 11.4 0.2 1.3 1 0 0 1 1 1 0 AMMECR1 DUF3450 PF11932.3 KEG15465.1 - 0.54 9.4 6.4 1.4 8.1 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) IncA PF04156.9 KEG15465.1 - 0.59 9.7 6.6 0.28 10.7 0.8 2.2 2 0 0 2 2 2 0 IncA protein CHASE3 PF05227.8 KEG15465.1 - 0.72 9.5 12.8 1.2 8.8 2.7 2.3 2 0 0 2 2 2 0 CHASE3 domain CorA PF01544.13 KEG15465.1 - 1.3 7.9 3.7 3.2 6.7 0.4 2.5 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein ATP-synt_DE_N PF02823.11 KEG15466.1 - 2e-15 56.3 0.0 2.9e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Ribosomal_S11 PF00411.14 KEG15467.1 - 1.1e-41 141.3 0.3 1.4e-41 141.1 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Pkinase PF00069.20 KEG15468.1 - 1.1e-38 132.8 0.0 1.2e-18 67.1 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEG15468.1 - 1.4e-08 34.1 0.0 3.7e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Astro_capsid PF03115.9 KEG15468.1 - 7.1 4.7 10.1 0.7 8.0 2.1 2.1 2 0 0 2 2 2 0 Astrovirus capsid protein precursor zf-CCCH PF00642.19 KEG15469.1 - 0.00035 20.1 1.0 0.00061 19.3 0.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KEG15469.1 - 0.018 15.0 1.6 0.043 13.8 1.1 1.7 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Mago_nashi PF02792.9 KEG15470.1 - 1.8e-57 193.0 0.2 2.1e-57 192.8 0.1 1.0 1 0 0 1 1 1 1 Mago nashi protein p450 PF00067.17 KEG15471.1 - 5.9e-47 160.2 0.0 7.5e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RF-1 PF00472.15 KEG15472.1 - 5.2e-12 45.5 0.0 1.2e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 RF-1 domain Rhodanese PF00581.15 KEG15473.1 - 0.0019 18.5 0.0 0.0031 17.8 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain S-AdoMet_synt_C PF02773.11 KEG15474.1 - 1.6e-71 238.4 0.2 2.4e-71 237.8 0.2 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 KEG15474.1 - 1.4e-46 157.3 0.0 2.3e-45 153.4 0.0 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 KEG15474.1 - 1.6e-38 130.9 0.1 3.3e-38 129.9 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Lactamase_B_3 PF13483.1 KEG15474.1 - 0.05 13.2 0.1 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 Beta-lactamase superfamily domain PDZ_2 PF13180.1 KEG15475.1 - 0.00014 21.7 0.0 0.00022 21.0 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 KEG15475.1 - 0.0048 17.0 0.0 0.0075 16.4 0.0 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) zf-MIZ PF02891.15 KEG15476.1 - 3.7e-16 58.3 9.2 6.1e-16 57.6 6.4 1.3 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger PWWP PF00855.12 KEG15476.1 - 3.6e-06 27.0 0.0 8.8e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 PWWP domain zf-Nse PF11789.3 KEG15476.1 - 0.0022 17.4 2.9 0.004 16.6 2.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Pkinase PF00069.20 KEG15478.1 - 3.8e-31 108.1 0.0 4.7e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG15478.1 - 5e-13 48.7 0.0 6e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase GAF PF01590.21 KEG15478.1 - 0.01 15.9 0.0 0.069 13.2 0.0 2.0 1 1 1 2 2 2 0 GAF domain Yippee-Mis18 PF03226.9 KEG15479.1 - 2.1e-17 62.9 0.4 2.6e-17 62.6 0.3 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.3 KEG15479.1 - 0.00033 20.5 0.4 0.0005 19.9 0.3 1.2 1 0 0 1 1 1 1 C-terminal domain of RIG-I Endonuclease_7 PF02945.10 KEG15479.1 - 0.046 13.4 2.2 0.068 12.8 1.5 1.3 1 0 0 1 1 1 0 Recombination endonuclease VII DUF3795 PF12675.2 KEG15479.1 - 0.27 11.4 3.6 6.4 7.0 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3795) Laminin_EGF PF00053.19 KEG15479.1 - 8.7 6.3 9.9 0.32 10.9 1.7 2.3 2 1 0 2 2 2 0 Laminin EGF-like (Domains III and V) TPR_11 PF13414.1 KEG15480.1 - 3.2e-10 39.5 3.8 0.00036 20.1 0.7 2.8 2 1 0 2 2 2 2 TPR repeat TPR_17 PF13431.1 KEG15480.1 - 4.6e-06 26.4 0.1 0.96 9.8 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEG15480.1 - 0.00072 20.1 9.4 0.18 12.5 0.2 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEG15480.1 - 0.0036 17.7 6.5 5.6 7.8 0.1 4.6 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 KEG15480.1 - 0.0071 16.1 5.3 0.17 11.7 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEG15480.1 - 0.014 15.3 5.4 3 7.9 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat tRNA_int_endo PF01974.12 KEG15481.1 - 0.005 16.6 0.0 0.0079 15.9 0.0 1.2 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain DNA_ligase_A_M PF01068.16 KEG15482.1 - 2.2e-58 196.9 0.0 5.7e-58 195.6 0.0 1.7 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KEG15482.1 - 1.4e-38 132.5 0.2 3.6e-38 131.1 0.0 1.8 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KEG15482.1 - 2.5e-26 91.9 0.0 1.8e-25 89.1 0.0 2.4 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 KEG15482.1 - 0.002 17.7 1.4 0.29 10.8 0.1 2.7 2 0 0 2 2 2 2 DNA ligase OB-like domain mRNA_cap_enzyme PF01331.14 KEG15482.1 - 0.08 12.6 0.0 0.32 10.6 0.0 1.8 2 0 0 2 2 2 0 mRNA capping enzyme, catalytic domain MKT1_C PF12246.3 KEG15483.1 - 6.8e-54 182.4 0.0 9.8e-54 181.9 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 KEG15483.1 - 8.8e-19 67.6 0.3 3.4e-18 65.7 0.1 2.1 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication Tcp11 PF05794.8 KEG15484.1 - 2.4e-18 66.0 0.0 1.9e-17 63.1 0.0 2.2 1 1 0 1 1 1 1 T-complex protein 11 WD40 PF00400.27 KEG15485.1 - 3e-09 36.3 9.4 0.077 12.9 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Dynein_heavy PF03028.10 KEG15485.1 - 5.6e-05 21.3 0.0 8.1e-05 20.8 0.0 1.1 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor PDZ_2 PF13180.1 KEG15485.1 - 0.013 15.3 0.1 1.9 8.4 0.0 2.7 2 0 0 2 2 2 0 PDZ domain RecR PF02132.10 KEG15486.1 - 0.00051 19.4 5.5 0.17 11.3 0.3 2.2 2 0 0 2 2 2 2 RecR protein PyrI_C PF02748.10 KEG15486.1 - 0.089 12.2 1.7 0.1 12.0 0.0 2.1 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-FCS PF06467.9 KEG15486.1 - 0.22 11.2 8.1 15 5.3 0.0 3.7 4 0 0 4 4 4 0 MYM-type Zinc finger with FCS sequence motif zinc_ribbon_4 PF13717.1 KEG15486.1 - 0.37 10.5 0.3 0.37 10.5 0.2 3.3 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 KEG15486.1 - 0.4 10.3 7.5 0.46 10.1 0.2 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Desulfoferrod_N PF06397.7 KEG15486.1 - 1.7 8.0 5.1 41 3.6 0.1 3.3 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain zf-tcix PF14952.1 KEG15486.1 - 2.8 7.3 11.4 0.61 9.4 2.3 2.3 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding C1_1 PF00130.17 KEG15486.1 - 4.4 7.1 14.0 20 5.0 0.4 3.9 2 1 2 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 KEG15486.1 - 4.4 7.0 9.1 15 5.3 0.8 3.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zinc_ribbon_2 PF13240.1 KEG15486.1 - 7.2 6.2 8.5 7.9 6.1 0.1 3.7 4 0 0 4 4 4 0 zinc-ribbon domain CAS_CSE1 PF03378.10 KEG15487.1 - 1.7e-85 286.9 0.1 8.8e-85 284.5 0.0 2.1 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 KEG15487.1 - 1.1e-61 208.5 0.0 1.6e-61 207.9 0.0 1.3 1 0 0 1 1 1 1 Cse1 HEAT_2 PF13646.1 KEG15487.1 - 2.4e-06 27.7 1.6 0.041 14.1 0.1 3.6 4 0 0 4 4 4 2 HEAT repeats IBN_N PF03810.14 KEG15487.1 - 0.00019 21.2 0.0 0.005 16.7 0.0 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KEG15487.1 - 0.0019 18.1 1.9 0.027 14.3 0.1 3.6 4 1 1 5 5 5 1 Exportin 1-like protein RIX1 PF08167.7 KEG15487.1 - 0.064 12.9 6.3 5.2 6.7 0.0 5.2 6 1 0 6 6 6 0 rRNA processing/ribosome biogenesis PGK PF00162.14 KEG15488.1 - 1e-131 439.0 0.0 1.3e-131 438.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoglycerate kinase PAS PF00989.19 KEG15488.1 - 4.3e-07 29.7 0.0 1e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 KEG15488.1 - 5.7e-06 26.6 0.0 1.6e-05 25.1 0.0 1.8 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.1 KEG15488.1 - 8.1e-05 22.3 0.0 0.00028 20.6 0.0 2.0 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.5 KEG15488.1 - 0.00039 20.4 0.0 0.001 19.1 0.0 1.7 1 0 0 1 1 1 1 PAS fold EF-hand_7 PF13499.1 KEG15489.1 - 4.2e-31 106.8 18.0 3.9e-09 36.5 0.1 6.1 5 2 0 5 5 5 3 EF-hand domain pair EF-hand_1 PF00036.27 KEG15489.1 - 4.5e-30 100.6 15.0 6.7e-05 21.9 0.1 8.8 8 0 0 8 8 8 6 EF hand EF-hand_8 PF13833.1 KEG15489.1 - 7.2e-23 79.9 10.9 0.0015 18.0 0.0 9.8 10 0 0 10 10 10 6 EF-hand domain pair EF-hand_6 PF13405.1 KEG15489.1 - 2.6e-22 76.6 18.7 8.3e-05 22.1 0.2 9.8 10 0 0 10 10 9 4 EF-hand domain EF-hand_5 PF13202.1 KEG15489.1 - 7.4e-19 66.1 9.5 0.00014 21.0 0.1 7.9 8 0 0 8 8 8 4 EF hand SPARC_Ca_bdg PF10591.4 KEG15489.1 - 0.00047 20.1 16.5 0.09 12.8 0.0 5.3 5 1 0 5 5 4 2 Secreted protein acidic and rich in cysteine Ca binding region Herpes_UL32 PF06070.6 KEG15489.1 - 0.01 14.3 11.7 0.014 13.9 8.1 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Ycf1 PF05758.7 KEG15489.1 - 0.43 8.2 8.3 0.62 7.7 5.7 1.1 1 0 0 1 1 1 0 Ycf1 MMR1 PF08505.5 KEG15489.1 - 0.47 10.4 15.7 0.91 9.5 10.9 1.5 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein RR_TM4-6 PF06459.7 KEG15489.1 - 0.73 9.6 15.3 1.4 8.7 10.6 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Trypan_PARP PF05887.6 KEG15489.1 - 1.4 8.7 10.5 2.6 7.8 7.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Hid1 PF12722.2 KEG15489.1 - 1.7 6.2 10.9 2.4 5.7 7.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GAGA_bind PF06217.7 KEG15489.1 - 2 8.2 13.0 3.6 7.4 9.0 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DUF3464 PF11947.3 KEG15489.1 - 3.5 7.0 8.3 6.5 6.2 5.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DDHD PF02862.12 KEG15489.1 - 4.9 6.8 11.0 9.2 5.9 7.6 1.5 1 0 0 1 1 1 0 DDHD domain DUF4011 PF13195.1 KEG15489.1 - 8.2 6.4 13.1 28 4.6 8.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) FLO_LFY PF01698.11 KEG15489.1 - 8.7 5.0 16.5 15 4.3 11.4 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Neur_chan_memb PF02932.11 KEG15489.1 - 9.5 6.0 6.4 16 5.2 4.4 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ribosomal_L6 PF00347.18 KEG15492.1 - 7.2e-26 90.4 3.2 1.6e-14 54.1 0.3 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 HSP20 PF00011.16 KEG15492.1 - 0.063 13.1 0.9 0.34 10.8 0.0 2.4 2 1 0 2 2 2 0 Hsp20/alpha crystallin family Hormone_2 PF00123.15 KEG15492.1 - 0.098 12.5 0.0 30 4.5 0.0 3.1 3 0 0 3 3 3 0 Peptide hormone DUF1488 PF07369.6 KEG15493.1 - 0.22 11.3 1.5 1.2 9.0 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1488) MORN PF02493.15 KEG15495.1 - 6.6e-97 311.8 111.3 6.6e-10 38.1 2.0 15.1 15 0 0 15 15 15 15 MORN repeat B-block_TFIIIC PF04182.7 KEG15495.1 - 0.51 10.2 2.1 9.8 6.1 0.0 3.7 4 1 1 5 5 5 0 B-block binding subunit of TFIIIC AA_permease_2 PF13520.1 KEG15496.1 - 1.8e-45 155.2 34.0 2.3e-45 154.9 23.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KEG15496.1 - 1e-32 113.1 32.0 1.4e-32 112.7 22.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.1 KEG15496.1 - 8.2e-09 35.2 6.2 8.2e-09 35.2 4.3 3.8 4 0 0 4 4 4 1 C-terminus of AA_permease XPC-binding PF09280.6 KEG15497.1 - 1.2e-17 63.0 5.6 2.3e-17 62.1 3.9 1.5 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.26 KEG15497.1 - 4.1e-17 61.4 3.5 1.2e-09 37.6 0.0 2.8 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.18 KEG15497.1 - 4e-09 35.7 0.2 7.5e-09 34.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KEG15497.1 - 8.5e-06 25.3 0.7 1.5e-05 24.5 0.2 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.5 KEG15497.1 - 0.0076 15.8 0.0 0.017 14.6 0.0 1.6 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain DUF1631 PF07793.6 KEG15497.1 - 0.13 10.3 0.3 0.91 7.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1631) TPR_2 PF07719.12 KEG15499.1 - 0.019 14.8 0.1 2 8.5 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 KEG15499.1 - 0.021 14.7 0.1 5.2 7.0 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 KEG15499.1 - 0.024 14.2 0.1 0.7 9.5 0.0 2.4 2 0 0 2 2 2 0 TPR repeat TPR_10 PF13374.1 KEG15499.1 - 0.079 12.9 0.2 3 7.8 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Metallophos PF00149.23 KEG15500.1 - 1.1e-09 38.0 0.6 2.9e-09 36.6 0.4 1.7 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase AA_permease_2 PF13520.1 KEG15501.1 - 0.038 12.5 0.4 0.04 12.4 0.3 1.1 1 0 0 1 1 1 0 Amino acid permease DUF3112 PF11309.3 KEG15501.1 - 0.047 13.4 0.2 0.058 13.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) Ank PF00023.25 KEG15502.1 - 1.5e-40 134.9 2.4 4e-08 32.6 0.0 6.7 6 0 0 6 6 6 6 Ankyrin repeat Ank_2 PF12796.2 KEG15502.1 - 9.5e-40 134.8 3.1 7.4e-15 55.0 0.3 4.0 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEG15502.1 - 2.3e-33 113.9 2.3 3.6e-09 36.8 0.0 6.1 2 2 5 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEG15502.1 - 4.7e-30 102.9 7.5 2.8e-08 33.7 0.0 6.7 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEG15502.1 - 2.8e-27 92.0 1.0 3.2e-05 23.7 0.0 6.9 6 1 1 7 7 7 6 Ankyrin repeat Erythro_esteras PF05139.9 KEG15502.1 - 0.27 10.3 7.2 0.47 9.6 4.7 1.5 2 0 0 2 2 2 0 Erythromycin esterase Helicase_C PF00271.26 KEG15503.1 - 3e-13 49.4 0.0 8.8e-13 47.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.18 KEG15503.1 - 4.8e-10 39.3 1.7 1.4e-09 37.9 0.0 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.24 KEG15503.1 - 2.1e-09 37.1 0.0 5.6e-09 35.7 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 KEG15503.1 - 1.5e-07 31.2 0.0 5.6e-07 29.3 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 KEG15503.1 - 4.9e-05 23.4 0.6 0.00028 21.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 KEG15503.1 - 0.0038 16.1 0.0 0.0071 15.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 KEG15503.1 - 0.018 14.4 0.0 0.052 13.0 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family YgbB PF02542.11 KEG15503.1 - 0.084 12.6 1.3 0.46 10.2 0.6 2.4 3 0 0 3 3 3 0 YgbB family AAA_23 PF13476.1 KEG15503.1 - 0.22 11.8 0.0 0.22 11.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain V_ATPase_I PF01496.14 KEG15503.1 - 5.6 4.6 11.8 11 3.6 8.2 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family tRNA-synt_1c PF00749.16 KEG15504.1 - 5e-98 327.6 0.1 6.6e-98 327.2 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KEG15504.1 - 1.5e-37 128.9 0.1 3.2e-37 127.8 0.1 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.14 KEG15504.1 - 0.012 14.7 0.0 0.024 13.7 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Adaptin_N PF01602.15 KEG15505.1 - 4.4e-97 325.6 4.3 5.8e-97 325.1 3.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 KEG15505.1 - 1.1e-07 32.0 5.4 8.3e-06 25.9 0.5 3.8 2 1 2 4 4 4 1 HEAT repeats Cnd1 PF12717.2 KEG15505.1 - 1.6e-05 24.8 3.2 0.00011 22.1 0.1 2.9 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KEG15505.1 - 2.4e-05 24.0 10.4 0.16 12.1 0.1 5.6 6 0 0 6 6 6 2 HEAT repeat Arm PF00514.18 KEG15505.1 - 0.0087 15.8 1.9 0.26 11.1 0.2 3.0 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat TLP-20 PF06088.6 KEG15505.1 - 0.069 12.8 10.0 0.31 10.6 1.2 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) PBP1_TM PF14812.1 KEG15505.1 - 0.27 11.5 22.0 2.8 8.2 7.9 2.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RasGEF_N_2 PF14663.1 KEG15505.1 - 0.39 10.6 2.3 2.2 8.2 0.1 2.6 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain HEAT_EZ PF13513.1 KEG15505.1 - 0.69 10.4 7.4 7.5 7.1 0.1 4.5 5 0 0 5 5 5 0 HEAT-like repeat FAM176 PF14851.1 KEG15505.1 - 1.8 8.2 12.9 2 8.0 2.9 2.5 2 0 0 2 2 2 0 FAM176 family Exo_endo_phos PF03372.18 KEG15506.1 - 5.2e-19 69.1 0.1 2.4e-15 57.1 0.0 2.2 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KEG15506.1 - 0.0012 18.4 0.0 1.4 8.5 0.0 2.5 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase HEAT PF02985.17 KEG15507.1 - 1.9e-07 30.5 6.8 0.37 10.9 0.0 6.6 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 KEG15507.1 - 1.3e-05 25.4 10.3 0.28 11.4 0.0 5.2 3 2 2 5 5 5 4 HEAT repeats Phage_lysozyme PF00959.14 KEG15508.1 - 0.0099 16.1 0.5 0.95 9.7 0.1 2.3 1 1 1 2 2 2 2 Phage lysozyme GST_C_2 PF13410.1 KEG15511.1 - 1e-10 41.3 0.0 2.4e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KEG15511.1 - 1.1e-05 25.8 0.0 4e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KEG15511.1 - 0.011 15.7 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain COG2 PF06148.6 KEG15512.1 - 3.5e-40 136.9 1.9 3.5e-40 136.9 1.3 2.4 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.3 KEG15512.1 - 1.3e-22 80.2 0.2 2.6e-20 72.7 0.0 3.1 3 1 0 3 3 3 2 Domain of unknown function (DUF3510) KIX PF02172.11 KEG15513.1 - 0.055 13.5 0.0 0.35 10.9 0.0 2.2 2 0 0 2 2 2 0 KIX domain MIF4G PF02854.14 KEG15514.1 - 2.2e-31 108.9 1.2 2.2e-31 108.9 0.8 1.8 2 0 0 2 2 2 1 MIF4G domain Zip PF02535.17 KEG15514.1 - 3.3e-05 23.0 7.7 5.5e-05 22.3 5.3 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter PAT1 PF09770.4 KEG15514.1 - 0.011 14.0 21.9 0.019 13.2 15.2 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4638 PF15472.1 KEG15514.1 - 0.061 12.9 5.7 0.16 11.5 4.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Otopetrin PF03189.8 KEG15514.1 - 0.071 12.0 0.2 0.11 11.5 0.2 1.3 1 0 0 1 1 1 0 Otopetrin DUF4175 PF13779.1 KEG15514.1 - 0.99 7.0 23.2 1.5 6.4 16.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CAP_N PF01213.14 KEG15514.1 - 1.5 7.9 7.2 3.3 6.9 5.0 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SMN PF06003.7 KEG15514.1 - 1.8 7.5 9.7 4.1 6.4 6.7 1.5 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) zf-LITAF-like PF10601.4 KEG15515.1 - 0.034 14.0 0.2 0.1 12.4 0.2 1.8 1 1 0 1 1 1 0 LITAF-like zinc ribbon domain Elf1 PF05129.8 KEG15515.1 - 0.038 13.6 0.5 0.038 13.6 0.3 2.3 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like RecR PF02132.10 KEG15515.1 - 0.46 9.9 4.3 0.75 9.2 0.5 2.5 2 0 0 2 2 2 0 RecR protein Peptidase_M8 PF01457.11 KEG15516.1 - 1.8e-85 287.3 0.0 2.3e-85 286.9 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M57 PF12388.3 KEG15516.1 - 0.042 13.1 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase SprT-like PF10263.4 KEG15516.1 - 0.055 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 SprT-like family Peptidase_S10 PF00450.17 KEG15519.1 - 5.1e-115 384.9 0.7 6.3e-115 384.6 0.5 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KEG15519.1 - 3.6e-05 23.7 0.1 0.051 13.4 0.0 2.5 2 1 0 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEG15519.1 - 0.082 12.1 0.1 0.18 11.0 0.1 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KEG15519.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KEG15519.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Cpn60_TCP1 PF00118.19 KEG15520.1 - 4.6e-141 470.7 8.9 5.2e-141 470.5 6.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CMS1 PF14617.1 KEG15520.1 - 0.017 14.2 0.4 0.097 11.7 0.2 2.1 1 1 1 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Pkinase PF00069.20 KEG15521.1 - 2.5e-74 249.7 0.0 2.9e-74 249.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEG15521.1 - 3e-31 108.4 0.0 3.7e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEG15521.1 - 0.0044 16.7 0.2 1 9.0 0.0 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Ribosom_S12_S23 PF00164.20 KEG15522.1 - 8.4e-39 131.7 0.6 1.1e-38 131.3 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_L6 PF00347.18 KEG15523.1 - 4.7e-26 91.0 3.2 1.1e-14 54.7 0.4 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 HSP20 PF00011.16 KEG15523.1 - 0.019 14.7 0.8 0.13 12.0 0.0 2.5 2 1 0 2 2 2 0 Hsp20/alpha crystallin family Hormone_2 PF00123.15 KEG15523.1 - 0.098 12.5 0.0 30 4.5 0.0 3.1 3 0 0 3 3 3 0 Peptide hormone Kinesin PF00225.18 KEG15524.1 - 3.5e-82 275.7 0.3 3.5e-82 275.7 0.2 2.1 2 0 0 2 2 2 1 Kinesin motor domain CAF-1_p150 PF11600.3 KEG15526.1 - 0.32 10.3 32.4 0.58 9.4 22.5 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ax_dynein_light PF10211.4 KEG15527.1 - 6e-63 212.1 3.1 7.1e-63 211.8 2.2 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain HAP1_N PF04849.8 KEG15527.1 - 0.0051 15.8 4.6 0.0071 15.3 3.2 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region DUF2353 PF09789.4 KEG15527.1 - 0.057 12.6 5.3 0.082 12.1 3.7 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) ORF6C PF10552.4 KEG15527.1 - 0.14 11.8 1.5 0.23 11.1 1.1 1.3 1 0 0 1 1 1 0 ORF6C domain DUF972 PF06156.8 KEG15527.1 - 0.22 11.8 7.3 0.09 13.1 3.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF972) APG6 PF04111.7 KEG15527.1 - 0.42 9.6 5.3 0.56 9.1 3.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Spc24 PF08286.6 KEG15527.1 - 1.4 8.6 5.4 2.6 7.7 3.8 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF904 PF06005.7 KEG15527.1 - 7.9 6.8 11.3 25 5.2 6.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF904) Tubulin PF00091.20 KEG15528.1 - 6.8e-72 241.7 0.0 1e-71 241.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KEG15528.1 - 7.7e-23 80.9 0.0 1.5e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KEG15528.1 - 0.0032 17.4 0.0 0.0057 16.7 0.0 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.1 KEG15528.1 - 0.017 14.1 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 Tubulin like Tubulin_3 PF14881.1 KEG15528.1 - 0.04 13.3 0.0 0.081 12.3 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain APG6 PF04111.7 KEG15529.1 - 0.45 9.5 19.5 0.066 12.2 2.4 2.4 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF972 PF06156.8 KEG15529.1 - 2 8.7 11.6 0.34 11.2 1.3 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Clathrin PF00637.15 KEG15531.1 - 7.4e-11 41.8 26.9 0.034 13.7 0.0 10.5 7 3 5 12 12 12 4 Region in Clathrin and VPS WD40 PF00400.27 KEG15531.1 - 7.6e-11 41.4 7.4 0.00082 19.1 0.1 5.8 5 0 0 5 5 5 3 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KEG15531.1 - 1.3e-05 24.1 11.2 0.0092 14.8 0.8 6.2 4 3 1 6 6 6 1 Coatomer WD associated region TPR_7 PF13176.1 KEG15531.1 - 0.00013 21.4 22.7 6.1 6.9 0.0 12.7 12 3 0 13 13 13 1 Tetratricopeptide repeat Apc3 PF12895.2 KEG15531.1 - 0.0026 17.8 32.1 0.22 11.6 0.1 9.8 7 2 4 11 11 11 1 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 KEG15531.1 - 0.0089 15.9 14.0 0.22 11.5 0.2 7.0 8 0 0 8 8 8 1 PPR repeat TPR_1 PF00515.23 KEG15531.1 - 0.023 14.2 35.2 10 5.9 0.0 11.7 11 2 2 13 13 12 0 Tetratricopeptide repeat TPR_12 PF13424.1 KEG15531.1 - 0.071 13.0 32.3 1.8 8.5 0.1 9.5 8 3 2 10 10 10 0 Tetratricopeptide repeat Utp13 PF08625.6 KEG15531.1 - 0.17 11.4 3.0 2.5 7.7 0.0 3.9 4 0 0 4 4 4 0 Utp13 specific WD40 associated domain TPR_2 PF07719.12 KEG15531.1 - 1 9.4 40.4 1.1 9.3 0.0 12.3 13 2 2 15 15 15 0 Tetratricopeptide repeat TPR_11 PF13414.1 KEG15531.1 - 3.2 7.4 42.8 5.2 6.7 0.0 11.6 10 3 2 12 12 12 0 TPR repeat PDCD2_C PF04194.8 KEG15534.1 - 3.4e-39 134.0 0.0 6.6e-39 133.1 0.0 1.4 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain AAA PF00004.24 KEG15535.1 - 4.2e-41 140.2 0.0 7e-41 139.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 KEG15535.1 - 2e-06 27.5 0.0 5.7e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 KEG15535.1 - 5.6e-05 23.3 0.1 0.00096 19.2 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KEG15535.1 - 0.00023 20.9 0.3 0.0018 18.0 0.2 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 KEG15535.1 - 0.00033 19.4 0.0 0.00064 18.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_2 PF07724.9 KEG15535.1 - 0.00037 20.4 0.0 0.00076 19.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 KEG15535.1 - 0.0005 19.9 0.1 0.0012 18.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KEG15535.1 - 0.00061 19.2 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 KEG15535.1 - 0.00092 18.6 0.7 0.13 11.6 0.2 2.5 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 KEG15535.1 - 0.0011 18.8 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Bac_DnaA PF00308.13 KEG15535.1 - 0.0013 18.4 0.0 0.0032 17.1 0.0 1.6 1 0 0 1 1 1 1 Bacterial dnaA protein AAA_19 PF13245.1 KEG15535.1 - 0.0014 18.3 0.0 0.0095 15.6 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 KEG15535.1 - 0.0015 19.3 0.0 0.0037 18.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KEG15535.1 - 0.0017 17.4 0.0 0.0032 16.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 KEG15535.1 - 0.0027 16.9 0.0 0.0049 16.0 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 KEG15535.1 - 0.003 17.5 0.0 0.0056 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.1 KEG15535.1 - 0.0036 16.8 0.0 1.7 8.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KEG15535.1 - 0.0047 16.6 0.0 0.11 12.1 0.0 2.5 2 1 1 3 3 3 1 NACHT domain CPT PF07931.7 KEG15535.1 - 0.011 15.4 0.1 0.13 11.9 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_24 PF13479.1 KEG15535.1 - 0.013 15.0 0.2 0.041 13.4 0.1 1.9 2 1 0 2 2 1 0 AAA domain AAA_28 PF13521.1 KEG15535.1 - 0.018 15.0 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KEG15535.1 - 0.036 14.3 0.1 0.1 12.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 KEG15535.1 - 0.044 13.0 0.1 0.081 12.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.17 KEG15535.1 - 0.074 13.2 0.0 0.25 11.5 0.0 2.0 2 0 0 2 2 1 0 RNA helicase Zeta_toxin PF06414.7 KEG15535.1 - 0.093 11.8 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DUF815 PF05673.8 KEG15535.1 - 0.11 11.4 0.0 0.22 10.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.1 KEG15535.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.1 KEG15539.1 - 0.0019 18.0 0.0 0.0041 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEG15539.1 - 0.022 14.7 0.0 0.06 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 KEG15539.1 - 0.039 13.3 0.0 0.076 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KEG15539.1 - 0.04 13.6 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase RecA PF00154.16 KEG15539.1 - 0.072 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein AAA_29 PF13555.1 KEG15539.1 - 0.13 11.7 0.0 0.49 9.9 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3333 PF11812.3 KEG15540.1 - 0.29 11.1 1.9 0.62 10.0 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3333) TPR_12 PF13424.1 KEG15541.1 - 0.0034 17.2 5.7 0.023 14.6 0.9 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat YbaB_DNA_bd PF02575.11 KEG15542.1 - 0.015 15.2 2.8 0.37 10.7 0.1 3.0 4 0 0 4 4 4 0 YbaB/EbfC DNA-binding family Exo_endo_phos PF03372.18 KEG15543.1 - 3.2e-16 60.0 0.0 5.1e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Methyltransf_31 PF13847.1 KEG15544.1 - 6.6e-10 38.7 0.0 9.6e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEG15544.1 - 1.5e-07 31.9 0.0 2.6e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEG15544.1 - 4.1e-07 29.5 0.0 7.9e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KEG15544.1 - 6e-06 26.2 0.1 1.6e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEG15544.1 - 5.9e-05 23.4 0.0 0.00011 22.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEG15544.1 - 0.0001 22.5 0.1 0.0002 21.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KEG15544.1 - 0.00012 21.3 0.0 0.00017 20.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.7 KEG15544.1 - 0.0016 18.9 0.0 0.0032 17.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 KEG15544.1 - 0.0034 18.1 0.0 0.0079 17.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 KEG15544.1 - 0.005 15.5 0.0 0.007 15.0 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase PRMT5 PF05185.11 KEG15544.1 - 0.1 11.5 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Myotub-related PF06602.9 KEG15545.1 - 5.3e-87 291.8 0.0 1e-86 290.9 0.0 1.5 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain FYVE PF01363.16 KEG15545.1 - 1.1e-12 47.6 10.6 1.1e-12 47.6 7.3 2.1 1 1 1 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.11 KEG15545.1 - 0.012 15.5 5.1 0.031 14.1 3.5 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger DSPc PF00782.15 KEG15545.1 - 0.098 12.2 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Helicase_C_2 PF13307.1 KEG15546.1 - 2.1e-43 148.1 0.0 6.7e-43 146.5 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 KEG15546.1 - 1.8e-26 92.5 0.6 1.8e-19 69.8 0.0 3.4 3 1 0 3 3 3 2 DEAD_2 ResIII PF04851.10 KEG15546.1 - 0.00022 21.1 0.2 0.52 10.1 0.0 3.3 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit DEAD PF00270.24 KEG15546.1 - 0.0013 18.2 0.0 0.051 13.0 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_19 PF13245.1 KEG15546.1 - 0.0015 18.2 0.1 0.0095 15.6 0.0 2.4 1 0 0 1 1 1 1 Part of AAA domain T2SE PF00437.15 KEG15546.1 - 0.09 11.6 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Arrestin_N PF00339.24 KEG15547.1 - 4.2e-12 46.1 0.0 1.4e-11 44.4 0.0 1.8 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 KEG15547.1 - 0.12 11.9 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Arrestin_N terminal like DUF1682 PF07946.9 KEG15548.1 - 0.22 10.3 3.2 0.29 9.9 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) ADH_zinc_N PF00107.21 KEG15550.1 - 1.7e-20 72.8 0.3 3.3e-20 71.9 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEG15550.1 - 2.3e-17 64.0 0.0 4.8e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEG15550.1 - 2.1e-10 40.3 1.9 8.4e-10 38.3 1.0 2.4 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AAA PF00004.24 KEG15552.1 - 6.7e-44 149.2 0.0 1.4e-43 148.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 KEG15552.1 - 1.2e-06 28.5 0.0 3.7e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KEG15552.1 - 1.7e-06 28.2 0.1 0.00047 20.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KEG15552.1 - 1.8e-06 27.7 0.1 1.4e-05 24.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KEG15552.1 - 3.2e-06 27.2 0.2 0.0016 18.4 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 KEG15552.1 - 2.1e-05 23.6 0.0 3.9e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 KEG15552.1 - 0.00011 21.6 0.4 0.01 15.2 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 KEG15552.1 - 0.00029 20.5 0.1 0.0011 18.6 0.1 2.0 2 0 0 2 2 2 1 Part of AAA domain IstB_IS21 PF01695.12 KEG15552.1 - 0.00032 20.1 0.1 0.00088 18.7 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein DUF815 PF05673.8 KEG15552.1 - 0.0013 17.7 0.0 0.0023 16.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 KEG15552.1 - 0.0014 19.4 0.2 0.0044 17.8 0.1 2.1 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KEG15552.1 - 0.0014 18.9 0.0 0.0035 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KEG15552.1 - 0.0019 17.0 0.0 0.0037 16.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_14 PF13173.1 KEG15552.1 - 0.0025 17.7 0.0 0.0047 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KEG15552.1 - 0.0041 16.3 0.0 0.0076 15.4 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KEG15552.1 - 0.0053 16.3 0.0 0.047 13.3 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KEG15552.1 - 0.0055 16.8 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Parvo_NS1 PF01057.12 KEG15552.1 - 0.012 14.5 0.0 0.024 13.5 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 KEG15552.1 - 0.015 14.7 0.1 0.1 12.0 0.1 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.1 KEG15552.1 - 0.016 15.0 0.0 0.052 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KEG15552.1 - 0.02 14.8 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KEG15552.1 - 0.025 13.8 0.3 0.07 12.3 0.0 1.9 2 0 0 2 2 1 0 PhoH-like protein ABC_tran PF00005.22 KEG15552.1 - 0.026 14.8 0.1 0.1 12.8 0.0 2.1 2 0 0 2 2 2 0 ABC transporter KaiC PF06745.8 KEG15552.1 - 0.027 13.5 2.2 0.27 10.3 0.0 2.9 2 1 1 3 3 3 0 KaiC NACHT PF05729.7 KEG15552.1 - 0.031 13.9 0.2 0.3 10.7 0.0 2.5 2 1 1 3 3 3 0 NACHT domain Arch_ATPase PF01637.13 KEG15552.1 - 0.037 13.7 0.1 0.55 9.8 0.0 2.4 2 1 0 2 2 1 0 Archaeal ATPase Zeta_toxin PF06414.7 KEG15552.1 - 0.041 12.9 0.0 0.1 11.6 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin Sigma54_activ_2 PF14532.1 KEG15552.1 - 0.049 13.6 0.1 0.18 11.8 0.0 2.1 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 KEG15552.1 - 0.056 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 KEG15552.1 - 0.082 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 KEG15552.1 - 0.28 10.5 1.7 2 7.8 0.0 2.4 2 1 0 3 3 3 0 AAA-like domain TruD PF01142.13 KEG15553.1 - 0.0018 16.9 0.0 0.0037 15.9 0.0 1.4 1 0 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) RRM_1 PF00076.17 KEG15554.1 - 4e-15 55.2 0.2 2.4e-07 30.2 0.0 4.3 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEG15554.1 - 8.9e-06 25.6 0.0 0.023 14.6 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEG15554.1 - 3e-05 23.7 0.0 0.003 17.3 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_C70 PF12385.3 KEG15554.1 - 0.055 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Papain-like cysteine protease AvrRpt2 THRAP3_BCLAF1 PF15440.1 KEG15554.1 - 4.7 5.7 35.3 0.016 13.9 17.9 1.6 2 0 0 2 2 2 0 THRAP3/BCLAF1 family DSPc PF00782.15 KEG15555.1 - 0.00019 21.0 0.1 0.0013 18.3 0.0 2.5 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain MscS_TM PF12794.2 KEG15556.1 - 0.44 9.1 19.4 0.023 13.3 6.3 2.6 1 1 1 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Ank_2 PF12796.2 KEG15557.1 - 3.9e-36 123.2 0.1 5.7e-17 61.8 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KEG15557.1 - 1.2e-32 110.0 0.1 8.8e-10 37.8 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 KEG15557.1 - 3.7e-28 96.9 3.1 2.1e-08 34.1 0.1 4.9 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEG15557.1 - 3.3e-21 73.2 0.7 0.00096 19.1 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 KEG15557.1 - 4.4e-21 74.8 0.6 2.7e-06 27.7 0.0 4.6 2 1 2 4 4 4 4 Ankyrin repeats (many copies) zf-DHHC PF01529.15 KEG15557.1 - 1.1e-05 24.8 2.9 1.1e-05 24.8 2.0 2.8 1 1 1 2 2 2 1 DHHC palmitoyltransferase TEX13 PF15186.1 KEG15557.1 - 0.21 11.1 0.0 0.38 10.3 0.0 1.3 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family DUF3481 PF11980.3 KEG15558.1 - 0.04 13.7 0.6 3.3 7.5 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3481) Nodulin PF02451.10 KEG15559.1 - 0.046 13.1 0.1 0.077 12.4 0.0 1.4 1 1 0 1 1 1 0 Nodulin TLD PF07534.11 KEG15561.1 - 1.7e-20 73.4 0.0 4.4e-20 72.0 0.0 1.7 1 0 0 1 1 1 1 TLD Ribosomal_60s PF00428.14 KEG15562.1 - 1.8e-22 79.5 8.5 2.1e-22 79.3 5.9 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Shadoo PF14999.1 KEG15562.1 - 1.6 8.5 9.3 0.34 10.7 3.3 1.9 2 1 0 2 2 2 0 Shadow of prion protein, neuroprotective MFS_1 PF07690.11 KEG15564.1 - 5.4e-28 97.7 28.0 1.6e-25 89.6 4.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 KEG15564.1 - 6.2e-05 21.2 2.2 0.00052 18.1 0.0 2.2 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Grp1_Fun34_YaaH PF01184.14 KEG15565.1 - 1.5e-59 200.8 9.3 1.8e-59 200.5 6.5 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family cNMP_binding PF00027.24 KEG15566.1 - 6.3e-25 86.8 0.1 5.5e-12 45.3 0.0 4.0 3 1 0 3 3 3 3 Cyclic nucleotide-binding domain DUF4300 PF14133.1 KEG15567.1 - 0.069 12.4 0.1 0.22 10.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4300) PemK PF02452.12 KEG15567.1 - 0.12 12.6 0.5 1.9 8.7 0.4 2.3 1 1 0 1 1 1 0 PemK-like protein RINGv PF12906.2 KEG15569.1 - 0.0027 17.7 1.4 0.0027 17.7 0.9 2.6 2 0 0 2 2 2 1 RING-variant domain PIN_4 PF13638.1 KEG15570.1 - 1.5e-07 31.6 0.0 4.5e-07 30.0 0.0 1.8 1 1 0 1 1 1 1 PIN domain HECT PF00632.20 KEG15571.1 - 2.6e-41 141.8 0.0 5.8e-41 140.6 0.0 1.5 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.23 KEG15571.1 - 1e-23 83.7 0.2 1.7e-08 34.6 0.0 4.7 4 0 0 4 4 4 4 SPRY domain ZZ PF00569.12 KEG15571.1 - 0.86 9.1 16.5 0.036 13.6 7.1 2.0 2 0 0 2 2 2 0 Zinc finger, ZZ type ResIII PF04851.10 KEG15572.1 - 2.2e-17 63.5 0.0 3.5e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KEG15572.1 - 4.5e-11 42.4 0.0 9.8e-11 41.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KEG15572.1 - 2.1e-08 33.3 0.0 4.5e-08 32.2 0.0 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C_3 PF13625.1 KEG15572.1 - 1.1e-07 31.6 0.0 3.4e-07 30.0 0.0 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEG15572.1 - 3.4e-05 23.4 0.0 0.00029 20.3 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Ribosomal_L2_C PF03947.13 KEG15573.1 - 2.6e-40 137.2 1.4 4.5e-40 136.4 1.0 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KEG15573.1 - 1.1e-12 47.7 0.0 2.7e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Peptidase_C54 PF03416.14 KEG15574.1 - 1.8e-53 181.5 0.0 2.4e-53 181.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Myosin_head PF00063.16 KEG15576.1 - 1.3e-169 565.5 4.1 9e-169 562.7 1.9 2.7 2 2 1 3 3 3 1 Myosin head (motor domain) UBA PF00627.26 KEG15576.1 - 1.2e-09 37.6 0.0 1.9e-05 24.3 0.0 3.1 2 0 0 2 2 2 2 UBA/TS-N domain AAA_22 PF13401.1 KEG15576.1 - 0.0098 16.0 0.0 0.076 13.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEG15576.1 - 0.016 15.2 1.7 0.66 9.9 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain CUE PF02845.11 KEG15576.1 - 0.037 13.5 0.0 39 3.8 0.0 3.6 3 0 0 3 3 3 0 CUE domain Hpr_kinase_C PF07475.7 KEG15576.1 - 0.047 12.9 0.1 1.3 8.3 0.1 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Mg_chelatase PF01078.16 KEG15576.1 - 0.073 12.2 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SNARE PF05739.14 KEG15577.1 - 9.9e-07 28.3 0.4 1.5e-06 27.7 0.2 1.3 1 0 0 1 1 1 1 SNARE domain DUF2562 PF10814.3 KEG15577.1 - 3 7.8 6.3 19 5.1 4.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2562) DUF2353 PF09789.4 KEG15579.1 - 7.7e-05 22.1 69.6 0.11 11.7 19.3 4.8 1 1 4 5 5 5 4 Uncharacterized coiled-coil protein (DUF2353) IncA PF04156.9 KEG15579.1 - 0.00012 21.7 95.2 0.27 10.7 10.9 5.9 1 1 4 5 5 5 3 IncA protein ATG16 PF08614.6 KEG15579.1 - 0.00012 21.9 20.1 0.00012 21.9 13.9 5.1 2 2 2 4 4 4 1 Autophagy protein 16 (ATG16) CCDC155 PF14662.1 KEG15579.1 - 0.00029 20.4 95.8 0.0033 17.0 16.0 5.2 1 1 3 4 4 4 3 Coiled-coil region of CCDC155 bZIP_1 PF00170.16 KEG15579.1 - 0.00099 19.0 66.8 0.012 15.5 3.1 11.0 5 4 6 12 12 12 5 bZIP transcription factor CENP-F_leu_zip PF10473.4 KEG15579.1 - 0.0019 18.0 26.5 0.0045 16.8 7.9 5.5 1 1 4 5 5 5 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HOOK PF05622.7 KEG15579.1 - 0.012 13.4 77.8 0.018 12.8 53.9 1.2 1 0 0 1 1 1 0 HOOK protein RecR PF02132.10 KEG15579.1 - 0.045 13.1 0.7 0.23 10.9 0.5 2.4 1 0 0 1 1 1 0 RecR protein DUF972 PF06156.8 KEG15579.1 - 0.15 12.3 71.1 0.025 14.9 2.6 8.2 1 1 7 8 8 8 0 Protein of unknown function (DUF972) Myosin_tail_1 PF01576.14 KEG15579.1 - 0.27 8.9 94.3 0.093 10.4 47.3 3.6 1 1 2 3 3 3 0 Myosin tail DUF3584 PF12128.3 KEG15579.1 - 1.5 6.0 77.6 0.0091 13.3 20.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) GAS PF13851.1 KEG15579.1 - 4.1 6.5 75.9 0.2 10.8 2.7 4.6 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 KEG15579.1 - 6.1 5.7 80.9 0.073 12.1 19.0 4.5 1 1 4 5 5 5 0 Autophagy protein Apg6 DUF869 PF05911.6 KEG15580.1 - 0.043 12.0 5.5 0.13 10.4 3.7 1.7 2 0 0 2 2 2 0 Plant protein of unknown function (DUF869) Filament PF00038.16 KEG15580.1 - 0.05 13.0 5.7 0.15 11.4 4.0 1.7 1 1 0 1 1 1 0 Intermediate filament protein DMPK_coil PF08826.5 KEG15580.1 - 0.12 12.2 9.7 0.42 10.5 1.7 2.8 2 1 0 2 2 2 0 DMPK coiled coil domain like UPF0184 PF03670.8 KEG15580.1 - 0.2 11.8 3.4 0.21 11.8 0.5 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) Shugoshin_N PF07558.6 KEG15580.1 - 0.33 10.7 2.2 7.5 6.3 0.1 2.4 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region TBPIP PF07106.8 KEG15580.1 - 0.38 10.2 4.0 0.51 9.8 1.8 1.7 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) APG6 PF04111.7 KEG15580.1 - 0.79 8.7 6.9 0.12 11.4 2.0 1.5 2 0 0 2 2 2 0 Autophagy protein Apg6 Spectrin PF00435.16 KEG15580.1 - 1 9.6 6.5 1.8 8.8 2.2 2.2 2 1 0 2 2 2 0 Spectrin repeat Mnd1 PF03962.10 KEG15580.1 - 1.2 8.8 5.4 1 8.9 2.0 1.9 2 0 0 2 2 2 0 Mnd1 family Cep57_CLD_2 PF14197.1 KEG15580.1 - 2.7 7.9 15.8 4.3 7.3 5.6 3.2 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 IncA PF04156.9 KEG15580.1 - 3.5 7.1 10.6 0.93 9.0 4.0 2.0 2 0 0 2 2 2 0 IncA protein bZIP_1 PF00170.16 KEG15580.1 - 3.9 7.5 10.5 6.5 6.7 1.3 3.2 3 1 0 3 3 3 0 bZIP transcription factor HALZ PF02183.13 KEG15580.1 - 9.7 6.0 13.2 3 7.6 0.1 3.8 4 0 0 4 4 4 0 Homeobox associated leucine zipper HEAT_2 PF13646.1 KEG15581.1 - 3.4e-11 43.2 25.6 0.0022 18.2 0.0 9.2 6 4 4 10 10 9 4 HEAT repeats HEAT_EZ PF13513.1 KEG15581.1 - 3.3e-10 40.1 41.2 0.001 19.5 0.0 11.8 9 4 4 13 13 13 5 HEAT-like repeat HEAT PF02985.17 KEG15581.1 - 1.4e-07 31.0 20.8 0.21 11.7 0.0 10.3 11 0 0 11 11 11 3 HEAT repeat IBN_N PF03810.14 KEG15581.1 - 4.5e-06 26.4 0.1 2.2e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain Arm PF00514.18 KEG15581.1 - 1.1e-05 25.0 2.2 8.2 6.4 0.0 6.9 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 KEG15581.1 - 6.4e-05 21.4 2.0 0.0037 15.6 0.1 3.4 3 0 0 3 3 3 1 Adaptin N terminal region CLASP_N PF12348.3 KEG15581.1 - 0.00014 21.2 0.2 9.4 5.5 0.0 5.1 3 2 2 5 5 5 1 CLASP N terminal DUF3554 PF12074.3 KEG15581.1 - 0.00025 20.5 0.1 0.035 13.5 0.0 3.6 3 1 1 4 4 4 1 Domain of unknown function (DUF3554) Ipi1_N PF12333.3 KEG15581.1 - 0.003 17.5 2.5 0.93 9.5 0.0 4.3 5 0 0 5 5 5 1 Rix1 complex component involved in 60S ribosome maturation Vac14_Fab1_bd PF12755.2 KEG15581.1 - 0.01 16.1 0.0 3.1 8.2 0.0 4.5 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region MMS22L_C PF14911.1 KEG15581.1 - 0.065 12.2 1.3 0.21 10.6 0.9 1.8 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, C-terminal Cornichon PF03311.9 KEG15582.1 - 0.0088 16.1 0.7 0.011 15.8 0.5 1.2 1 0 0 1 1 1 1 Cornichon protein DUF3537 PF12056.3 KEG15582.1 - 0.048 12.3 0.4 0.054 12.1 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3537) PqiA PF04403.8 KEG15582.1 - 0.11 12.0 0.4 0.11 12.0 0.3 1.9 1 1 1 2 2 2 0 Paraquat-inducible protein A DUF898 PF05987.8 KEG15582.1 - 0.27 10.0 5.9 0.32 9.8 4.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF4234 PF14018.1 KEG15582.1 - 9.1 6.1 6.9 16 5.3 4.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) DUF4191 PF13829.1 KEG15583.1 - 0.024 13.7 0.1 0.027 13.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Tic20 PF09685.5 KEG15583.1 - 0.097 12.6 1.7 0.13 12.2 1.2 1.2 1 0 0 1 1 1 0 Tic20-like protein DUF1360 PF07098.6 KEG15583.1 - 0.62 9.8 4.6 0.86 9.3 3.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1360) DUF2628 PF10947.3 KEG15583.1 - 0.7 9.7 4.1 1.1 9.0 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) WD40 PF00400.27 KEG15584.1 - 0.012 15.4 3.2 5.3 7.0 0.0 3.9 4 1 1 5 5 5 0 WD domain, G-beta repeat SHQ1 PF04925.10 KEG15585.1 - 3.2e-53 179.9 0.0 5.8e-53 179.1 0.0 1.3 1 0 0 1 1 1 1 SHQ1 protein TPR_11 PF13414.1 KEG15586.1 - 1.2e-10 40.8 0.0 3.8e-05 23.2 0.0 2.8 2 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KEG15586.1 - 5.6e-08 32.1 1.3 0.013 15.3 0.0 3.8 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 KEG15586.1 - 5.1e-07 29.0 1.2 0.0049 16.4 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEG15586.1 - 6.6e-07 29.1 0.1 0.002 18.0 0.1 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 KEG15586.1 - 3e-06 26.9 5.1 8.5e-05 22.3 0.8 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEG15586.1 - 0.00029 20.3 0.1 0.68 9.8 0.0 3.0 3 1 0 3 3 2 2 Tetratricopeptide repeat DUF3856 PF12968.2 KEG15586.1 - 0.0003 20.6 0.1 0.00082 19.2 0.1 1.7 1 1 0 1 1 1 1 Domain of Unknown Function (DUF3856) TPR_7 PF13176.1 KEG15586.1 - 0.00044 19.8 0.3 0.01 15.5 0.0 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 KEG15586.1 - 0.0056 16.5 0.2 0.37 10.7 0.0 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KEG15586.1 - 0.03 14.9 2.4 0.37 11.5 0.2 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat RPN7 PF10602.4 KEG15586.1 - 0.13 11.6 0.1 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 26S proteasome subunit RPN7 TPR_4 PF07721.9 KEG15586.1 - 0.47 11.0 5.7 1.7 9.3 0.0 4.4 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 KEG15586.1 - 0.64 10.7 4.4 3.6 8.3 0.3 3.4 3 2 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEG15586.1 - 0.79 10.3 4.4 33 5.2 0.0 3.5 4 1 0 4 4 4 0 Tetratricopeptide repeat ATG27 PF09451.5 KEG15587.1 - 5.5e-11 42.2 0.1 2.5e-10 40.0 0.0 1.8 2 0 0 2 2 2 1 Autophagy-related protein 27 Man-6-P_recep PF02157.10 KEG15587.1 - 2.6e-05 23.3 0.2 3.7e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor DUF2244 PF10003.4 KEG15587.1 - 0.18 11.1 0.4 0.34 10.2 0.3 1.4 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) CKS PF01111.14 KEG15588.1 - 2.3e-36 123.4 2.0 3.1e-36 123.0 1.4 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DUF1965 PF09248.5 KEG15588.1 - 0.019 14.8 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1965) Enolase_N PF03952.11 KEG15590.1 - 9.4e-11 41.7 0.1 1.9e-10 40.7 0.0 1.6 2 0 0 2 2 2 1 Enolase, N-terminal domain Enolase_C PF00113.17 KEG15590.1 - 1.1e-05 24.5 0.0 1.6e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain TMEM18 PF14770.1 KEG15592.1 - 5.4e-33 113.1 5.6 6.5e-33 112.8 3.9 1.1 1 0 0 1 1 1 1 Transmembrane protein 18 DUF3733 PF12534.3 KEG15592.1 - 0.14 11.5 0.6 0.29 10.4 0.4 1.6 1 0 0 1 1 1 0 Leucine-rich repeat containing protein 8 DUF4282 PF14110.1 KEG15592.1 - 4.1 7.6 9.1 9.5 6.4 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4282) zinc-ribbons_6 PF07191.7 KEG15593.1 - 0.075 12.8 2.1 0.15 11.8 1.4 1.5 1 0 0 1 1 1 0 zinc-ribbons FIST_C PF10442.4 KEG15594.1 - 0.027 14.4 0.1 0.096 12.6 0.1 1.9 1 0 0 1 1 1 0 FIST C domain DUF1840 PF08895.6 KEG15595.1 - 0.3 11.1 2.6 0.99 9.4 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) ECH_C PF13766.1 KEG15596.1 - 1.6e-34 118.5 0.0 3.2e-34 117.5 0.0 1.5 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 KEG15596.1 - 1.6e-24 86.3 0.0 2e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 KEG15597.1 - 1.2e-42 144.7 0.1 6.4e-31 106.9 0.0 2.2 1 1 1 2 2 2 2 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 KEG15597.1 - 2.4e-23 82.5 0.0 6.1e-23 81.2 0.0 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF460 PF04312.8 KEG15598.1 - 0.071 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF460) PH_6 PF15406.1 KEG15600.1 - 0.0051 16.8 0.3 0.014 15.4 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 KEG15600.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 PH domain zf-CCCH PF00642.19 KEG15602.1 - 5.3e-08 32.3 4.4 8.5e-08 31.7 3.0 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KEG15602.1 - 0.0074 16.2 1.9 0.0086 16.0 0.3 1.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type DnaJ PF00226.26 KEG15603.1 - 1.5e-11 43.8 0.1 3.4e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain DUF4339 PF14237.1 KEG15603.1 - 2.9e-11 42.7 0.9 6.1e-11 41.7 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4339) UPF0004 PF00919.15 KEG15604.1 - 9.5e-20 70.2 0.0 2.3e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.16 KEG15604.1 - 1.4e-18 67.6 0.1 3.8e-18 66.2 0.1 1.7 2 0 0 2 2 2 1 Radical SAM superfamily TRAM PF01938.15 KEG15604.1 - 2.9e-05 23.7 0.1 6.2e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 TRAM domain DUF155 PF02582.9 KEG15605.1 - 1.6e-15 57.4 0.0 2.8e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Mito_carr PF00153.22 KEG15606.1 - 7.8e-07 28.7 9.1 0.066 12.9 0.1 4.6 3 2 1 4 4 4 4 Mitochondrial carrier protein DUF204 PF02659.10 KEG15606.1 - 0.11 12.5 1.1 0.28 11.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF zf-C2H2_2 PF12756.2 KEG15607.1 - 9.6e-27 93.0 9.6 1.8e-19 69.7 0.0 3.3 2 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KEG15607.1 - 2e-10 40.5 8.8 5.1e-06 26.4 0.3 3.7 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KEG15607.1 - 3.8e-08 32.9 13.8 0.0042 16.9 0.2 4.2 4 1 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.2 KEG15607.1 - 9.1e-07 28.8 11.5 7.7e-05 22.7 0.6 3.5 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 KEG15607.1 - 4e-06 26.7 11.9 0.039 14.2 0.5 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KEG15607.1 - 0.00056 20.1 4.4 0.01 16.1 0.5 4.3 4 1 0 4 4 3 2 Zinc finger, C2H2 type zf-BED PF02892.10 KEG15607.1 - 0.0073 16.0 3.9 3.6 7.4 0.0 4.0 4 0 0 4 4 4 1 BED zinc finger DUF1993 PF09351.5 KEG15607.1 - 1.1 9.1 4.1 0.34 10.8 0.1 2.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1993) Yippee-Mis18 PF03226.9 KEG15607.1 - 1.7 8.7 4.6 27 4.8 0.3 3.4 2 1 1 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly E6 PF00518.12 KEG15607.1 - 3.6 7.9 7.4 15 5.9 0.0 3.7 3 1 1 4 4 3 0 Early Protein (E6) SAE2 PF08573.5 KEG15607.1 - 6.7 7.4 12.0 0.18 12.4 0.6 3.2 3 1 0 3 3 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus TFIIS_C PF01096.13 KEG15607.1 - 6.8 6.4 7.1 0.37 10.4 0.2 2.5 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) E1-E2_ATPase PF00122.15 KEG15608.1 - 1e-10 41.0 0.0 3.8e-10 39.1 0.0 2.0 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KEG15608.1 - 4.1e-10 40.4 1.3 0.00076 19.9 0.3 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEG15608.1 - 9e-10 39.0 0.0 2.6e-09 37.5 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEG15608.1 - 1.1e-08 34.9 0.0 2.4e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KEG15608.1 - 0.0026 17.4 0.1 0.0054 16.3 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase LRR_4 PF12799.2 KEG15609.1 - 8.5e-28 95.4 16.5 2.6e-06 26.8 1.6 6.1 4 1 1 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEG15609.1 - 1.6e-13 50.1 23.7 9.3e-06 25.3 1.8 5.0 2 1 5 7 7 7 7 Leucine rich repeat LRR_6 PF13516.1 KEG15609.1 - 4.2e-07 29.3 12.2 0.61 10.3 0.3 8.1 8 1 0 8 8 8 2 Leucine Rich repeat LRR_1 PF00560.28 KEG15609.1 - 8.8e-06 25.0 24.6 2 8.7 0.5 9.6 9 2 1 10 10 10 3 Leucine Rich Repeat LRR_9 PF14580.1 KEG15609.1 - 1.1e-05 25.0 6.4 0.00087 18.8 0.1 3.9 1 1 3 4 4 4 2 Leucine-rich repeat LRR_7 PF13504.1 KEG15609.1 - 0.00076 19.2 25.8 2.5 8.6 0.3 9.4 9 1 1 10 10 10 2 Leucine rich repeat TTL PF03133.10 KEG15610.1 - 3.1e-51 174.0 0.0 2.1e-31 108.9 0.0 2.1 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 KEG15610.1 - 3.3e-07 29.3 0.0 0.0072 15.1 0.0 2.6 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 KEG15610.1 - 0.0058 16.3 0.0 0.023 14.4 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KEG15610.1 - 0.015 14.6 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus CP_ATPgrasp_1 PF04174.8 KEG15610.1 - 0.17 10.4 0.0 0.3 9.6 0.0 1.3 1 0 0 1 1 1 0 A circularly permuted ATPgrasp PhyH PF05721.8 KEG15611.1 - 1.6e-23 83.8 0.0 2.1e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Helicase_C PF00271.26 KEG15612.1 - 6e-16 58.0 0.1 2.2e-15 56.2 0.2 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEG15612.1 - 9.8e-16 57.7 0.0 4.2e-15 55.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase SET PF00856.23 KEG15615.1 - 1.4e-09 38.4 0.0 2.2e-08 34.5 0.0 2.1 2 0 0 2 2 2 1 SET domain TMF_TATA_bd PF12325.3 KEG15616.1 - 0.004 16.8 3.5 0.004 16.8 2.4 2.6 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding zf-C2H2 PF00096.21 KEG15616.1 - 0.024 14.9 4.6 0.063 13.6 3.2 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF2216 PF10226.4 KEG15616.1 - 0.032 13.7 0.1 0.032 13.7 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized conserved proteins (DUF2216) DUF3492 PF11997.3 KEG15616.1 - 0.099 12.1 2.9 0.57 9.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3492) ERM PF00769.14 KEG15616.1 - 0.15 11.5 15.7 0.044 13.3 1.6 2.7 2 0 0 2 2 2 0 Ezrin/radixin/moesin family zf-C2H2_4 PF13894.1 KEG15616.1 - 0.2 12.0 3.5 0.65 10.4 2.4 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger DUF3450 PF11932.3 KEG15616.1 - 0.28 10.4 10.9 1.1 8.5 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DivIC PF04977.10 KEG15616.1 - 0.38 10.2 12.2 0.11 12.0 0.9 2.5 2 0 0 2 2 2 0 Septum formation initiator Dzip-like_N PF13815.1 KEG15616.1 - 1.8 8.3 15.3 0.029 14.1 3.6 2.5 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal DUF3509 PF12021.3 KEG15616.1 - 3.5 7.4 10.3 0.49 10.1 3.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3509) BBS2_C PF14782.1 KEG15616.1 - 3.7 6.0 11.9 3.6 6.0 0.6 2.2 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal Pyridoxal_deC PF00282.14 KEG15617.1 - 6.7e-20 70.8 0.0 1.3e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KEG15617.1 - 0.00052 18.8 0.0 0.002 16.9 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KEG15617.1 - 0.0015 17.6 0.0 0.0031 16.6 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family zf-B_box PF00643.19 KEG15618.1 - 9.1e-09 35.0 28.9 2.2e-06 27.4 5.5 3.9 4 0 0 4 4 4 2 B-box zinc finger zf-C3HC4 PF00097.20 KEG15618.1 - 1.4e-07 31.0 8.1 1.4e-07 31.0 5.6 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KEG15618.1 - 1.8e-07 30.8 9.1 1.8e-07 30.8 6.3 3.6 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 KEG15618.1 - 0.00033 20.6 8.0 0.00033 20.6 5.6 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEG15618.1 - 0.00047 19.8 8.6 0.00047 19.8 5.9 3.4 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.1 KEG15618.1 - 0.00067 19.4 7.3 0.00067 19.4 5.1 3.4 3 0 0 3 3 3 1 Ring finger domain zf-MIZ PF02891.15 KEG15618.1 - 0.015 14.8 4.4 0.015 14.8 3.1 2.4 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger C1_4 PF07975.7 KEG15618.1 - 0.016 15.2 2.0 0.016 15.2 1.4 4.0 3 1 0 3 3 3 0 TFIIH C1-like domain Spc7 PF08317.6 KEG15618.1 - 0.065 11.8 1.5 0.096 11.3 1.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Arf PF00025.16 KEG15619.1 - 5.3e-49 165.8 0.0 6.1e-49 165.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KEG15619.1 - 3.2e-14 52.5 0.0 4.3e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KEG15619.1 - 2e-10 40.6 0.0 2.6e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KEG15619.1 - 3e-10 40.6 0.0 4.8e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 KEG15619.1 - 9.1e-10 37.7 0.0 1.4e-07 30.5 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit Ras PF00071.17 KEG15619.1 - 1.5e-09 37.4 0.0 2.1e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KEG15619.1 - 3e-05 23.2 0.0 6.6e-05 22.1 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 KEG15619.1 - 3e-05 23.3 0.0 7.5e-05 22.0 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KEG15619.1 - 0.00011 21.7 0.0 0.0011 18.4 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain cobW PF02492.14 KEG15619.1 - 0.0081 15.6 0.0 2.2 7.7 0.0 2.1 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 KEG15619.1 - 0.026 14.2 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase CdhD PF03599.11 KEG15619.1 - 0.034 12.6 0.0 0.043 12.2 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit MobB PF03205.9 KEG15619.1 - 0.045 13.4 0.0 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 KEG15619.1 - 0.05 13.4 0.0 0.41 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KEG15619.1 - 0.083 13.1 0.0 0.17 12.1 0.0 1.7 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.1 KEG15619.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KEG15619.1 - 0.13 11.7 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Septin PF00735.13 KEG15619.1 - 0.13 11.2 0.0 0.35 9.8 0.0 1.6 2 0 0 2 2 2 0 Septin DUF4140 PF13600.1 KEG15620.1 - 0.39 11.1 24.1 0.14 12.6 1.9 3.3 2 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF3293 PF11697.3 KEG15620.1 - 1.8 8.7 9.3 8 6.6 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3293) CALCOCO1 PF07888.6 KEG15620.1 - 4.5 5.4 21.7 3.3 5.9 10.2 2.1 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Mito_fiss_reg PF05308.6 KEG15621.1 - 0.13 11.5 3.0 0.25 10.7 2.1 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 KEG15621.1 - 1.3 8.2 5.2 2.4 7.3 3.6 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Vps26 PF03643.10 KEG15622.1 - 1.2e-21 76.6 0.0 1e-20 73.6 0.0 1.9 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 KEG15622.1 - 1.2e-05 25.1 0.0 4.9e-05 23.1 0.0 2.0 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Clp1 PF06807.9 KEG15624.1 - 3.2e-29 102.1 0.0 5.2e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 KEG15624.1 - 5.1e-15 55.4 0.0 8.3e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KEG15624.1 - 0.0037 17.2 0.0 0.0079 16.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KEG15624.1 - 0.0063 17.0 0.0 0.011 16.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 KEG15624.1 - 0.034 13.9 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 Dynamin family DUF815 PF05673.8 KEG15624.1 - 0.049 12.5 0.0 0.08 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_16 PF13191.1 KEG15624.1 - 0.05 13.5 0.0 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 KEG15624.1 - 0.076 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 KEG15624.1 - 0.078 12.5 0.0 0.82 9.2 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_17 PF13207.1 KEG15624.1 - 0.12 13.2 0.0 0.32 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KEG15624.1 - 0.13 12.6 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain PTH2 PF01981.11 KEG15625.1 - 2.3e-19 69.1 0.1 6.5e-19 67.7 0.0 1.8 2 0 0 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 DUF1510 PF07423.6 KEG15625.1 - 5.5e-05 22.6 1.6 7.7e-05 22.1 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Pox_Ag35 PF03286.9 KEG15625.1 - 0.026 14.0 6.1 0.042 13.3 4.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SDA1 PF05285.7 KEG15625.1 - 0.098 11.9 11.8 0.13 11.4 8.2 1.1 1 0 0 1 1 1 0 SDA1 Zip PF02535.17 KEG15625.1 - 0.17 10.8 0.1 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.11 KEG15625.1 - 0.18 11.6 0.1 0.21 11.4 0.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Cwf_Cwc_15 PF04889.7 KEG15625.1 - 0.19 11.4 13.7 0.26 10.9 9.5 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop25 PF09805.4 KEG15625.1 - 0.3 11.1 13.0 0.42 10.6 9.0 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Ycf1 PF05758.7 KEG15625.1 - 0.4 8.3 1.8 0.47 8.1 1.2 1.0 1 0 0 1 1 1 0 Ycf1 TRAP_alpha PF03896.11 KEG15625.1 - 0.41 9.5 6.2 0.59 9.0 4.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DDRGK PF09756.4 KEG15625.1 - 0.42 9.9 11.5 0.5 9.7 8.0 1.1 1 0 0 1 1 1 0 DDRGK domain RNA_pol_3_Rpc31 PF11705.3 KEG15625.1 - 1 9.2 15.4 1.4 8.7 10.7 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 UPF0560 PF10577.4 KEG15625.1 - 3 5.9 6.7 4 5.5 4.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 CDC45 PF02724.9 KEG15625.1 - 4.7 5.1 14.3 6.1 4.7 9.9 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.7 KEG15625.1 - 4.8 6.2 14.8 6.6 5.7 10.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TPR_11 PF13414.1 KEG15627.1 - 5.4e-05 22.7 5.4 0.0001 21.9 1.2 2.2 2 1 1 3 3 3 2 TPR repeat TPR_16 PF13432.1 KEG15627.1 - 0.0018 18.8 9.2 0.15 12.8 4.8 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEG15627.1 - 0.0064 16.3 3.5 0.33 10.9 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEG15627.1 - 0.0088 16.3 1.7 0.56 10.5 1.2 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 KEG15627.1 - 0.061 13.4 1.8 0.095 12.8 0.1 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KEG15627.1 - 0.1 12.4 2.8 0.62 9.9 0.1 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEG15627.1 - 0.34 11.6 8.2 2.1 9.2 2.1 3.8 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 KEG15627.1 - 0.51 10.3 4.5 2 8.4 2.3 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat DnaJ PF00226.26 KEG15628.1 - 2.4e-14 52.7 0.0 5.5e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain HSP70 PF00012.15 KEG15629.1 - 1.5e-263 875.1 6.5 1.9e-263 874.9 4.5 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KEG15629.1 - 3.7e-14 52.0 2.3 2.8e-13 49.1 0.2 2.5 3 0 0 3 3 3 1 MreB/Mbl protein FtsA PF14450.1 KEG15629.1 - 0.00043 20.1 7.3 1.1 9.1 0.0 4.6 4 2 0 4 4 4 2 Cell division protein FtsA FGGY_C PF02782.11 KEG15629.1 - 0.013 15.1 0.0 0.037 13.6 0.0 1.8 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 KEG15629.1 - 0.14 11.2 8.3 1.3 8.0 0.1 3.7 3 1 0 4 4 4 0 Hydantoinase/oxoprolinase CorA PF01544.13 KEG15629.1 - 0.2 10.6 2.1 0.32 10.0 1.5 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein FAD-SLDH PF12318.3 KEG15630.1 - 0.027 14.1 0.1 0.066 12.9 0.0 1.6 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase PAP_assoc PF03828.14 KEG15630.1 - 0.075 12.9 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 Cid1 family poly A polymerase pKID PF02173.12 KEG15631.1 - 0.056 12.6 0.0 13 5.1 0.0 2.5 2 0 0 2 2 2 0 pKID domain Allexi_40kDa PF05549.6 KEG15631.1 - 1.7 7.8 6.2 0.63 9.2 0.7 2.8 2 1 0 3 3 3 0 Allexivirus 40kDa protein Cofilin_ADF PF00241.15 KEG15632.1 - 4.5e-05 23.3 0.0 0.016 15.0 0.0 3.0 3 0 0 3 3 3 2 Cofilin/tropomyosin-type actin-binding protein MutS_III PF05192.13 KEG15632.1 - 0.11 12.2 0.1 0.14 11.9 0.0 1.3 1 1 0 1 1 1 0 MutS domain III Pox_F12L PF03337.8 KEG15632.1 - 0.17 9.7 0.0 0.24 9.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus F12L protein JAB PF01398.16 KEG15634.1 - 4.9e-32 110.0 0.0 7.2e-32 109.5 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 KEG15634.1 - 8.3e-10 38.1 0.0 1.3e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain MitMem_reg PF13012.1 KEG15634.1 - 1.8e-08 34.4 0.0 3e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UPF0172 PF03665.8 KEG15634.1 - 0.0045 16.4 0.0 0.0071 15.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) AAA_12 PF13087.1 KEG15635.1 - 3.8e-26 91.7 0.0 1.1e-25 90.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KEG15635.1 - 1.4e-16 60.7 1.0 8.4e-09 35.3 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 KEG15635.1 - 7.5e-08 32.1 0.0 0.00013 21.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KEG15635.1 - 1e-05 25.1 0.0 3.6e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KEG15635.1 - 0.00032 20.8 0.2 0.074 13.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.16 KEG15635.1 - 0.0012 18.2 0.2 0.0066 15.7 0.0 2.2 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain Terminase_2 PF03592.11 KEG15635.1 - 0.014 15.7 0.2 0.014 15.7 0.2 2.0 2 0 0 2 2 2 0 Terminase small subunit DUF2075 PF09848.4 KEG15635.1 - 0.014 14.3 0.1 0.041 12.8 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 KEG15635.1 - 0.018 14.1 0.0 0.059 12.4 0.0 1.9 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.1 KEG15635.1 - 0.12 11.7 0.1 0.92 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain ERM PF00769.14 KEG15636.1 - 0.0042 16.6 19.1 0.0042 16.6 13.2 4.7 3 2 1 4 4 4 1 Ezrin/radixin/moesin family DUF3292 PF11696.3 KEG15637.1 - 0.0061 14.5 0.2 0.017 13.0 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) DUF1897 PF09005.5 KEG15638.1 - 0.14 11.6 0.4 0.27 10.7 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1897) FOP_dimer PF09398.5 KEG15640.1 - 0.0029 17.5 0.0 0.0087 16.0 0.0 1.8 1 0 0 1 1 1 1 FOP N terminal dimerisation domain Spc7 PF08317.6 KEG15640.1 - 0.012 14.2 10.4 0.011 14.3 6.1 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein AAA_13 PF13166.1 KEG15640.1 - 0.11 10.9 4.3 0.17 10.2 3.0 1.2 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.4 KEG15640.1 - 1.4 7.8 21.8 3.9 6.3 14.0 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Plasmodium_Vir PF05795.6 KEG15640.1 - 2 7.5 3.8 3.3 6.8 2.6 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF1426 PF07234.6 KEG15640.1 - 2.6 7.8 5.6 19 5.0 0.6 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1426) Bot1p PF12298.3 KEG15641.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic mitochondrial regulator protein Osmo_CC PF08946.5 KEG15642.1 - 0.0013 18.7 3.4 0.0026 17.7 2.4 1.5 1 0 0 1 1 1 1 Osmosensory transporter coiled coil Phage_GP20 PF06810.6 KEG15642.1 - 0.0067 15.8 5.8 0.0067 15.8 4.1 1.5 1 1 0 1 1 1 1 Phage minor structural protein GP20 BLOC1_2 PF10046.4 KEG15642.1 - 0.014 15.5 1.5 0.02 14.9 1.0 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.7 KEG15642.1 - 0.072 13.3 0.9 0.1 12.8 0.6 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein HR1 PF02185.11 KEG15642.1 - 0.077 12.7 3.1 0.12 12.1 2.2 1.3 1 0 0 1 1 1 0 Hr1 repeat FlxA PF14282.1 KEG15642.1 - 0.078 12.9 1.5 0.078 12.9 1.0 1.7 2 1 0 2 2 2 0 FlxA-like protein FlgM PF04316.8 KEG15642.1 - 0.078 12.9 0.8 0.14 12.1 0.5 1.5 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM Caudo_TAP PF02413.12 KEG15642.1 - 0.081 13.0 1.7 0.092 12.9 1.2 1.1 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein Hanta_nucleocap PF00846.13 KEG15642.1 - 0.083 11.5 4.0 0.097 11.3 2.8 1.1 1 0 0 1 1 1 0 Hantavirus nucleocapsid protein PRP1_N PF06424.7 KEG15642.1 - 0.11 12.8 7.9 0.13 12.6 5.5 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal SlyX PF04102.7 KEG15642.1 - 0.11 12.8 1.9 0.14 12.5 0.8 1.6 1 1 1 2 2 2 0 SlyX Prefoldin PF02996.12 KEG15642.1 - 0.13 11.9 2.5 0.19 11.3 1.7 1.4 1 1 0 1 1 1 0 Prefoldin subunit ApoO PF09769.4 KEG15642.1 - 0.16 11.6 0.4 0.19 11.3 0.3 1.2 1 0 0 1 1 1 0 Apolipoprotein O TMF_DNA_bd PF12329.3 KEG15642.1 - 0.17 11.7 7.3 0.077 12.8 2.9 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding YlbD_coat PF14071.1 KEG15642.1 - 0.18 11.8 4.2 0.21 11.6 2.9 1.2 1 0 0 1 1 1 0 Putative coat protein IncA PF04156.9 KEG15642.1 - 0.26 10.8 2.8 0.32 10.5 1.9 1.3 1 0 0 1 1 1 0 IncA protein YgaB PF14182.1 KEG15642.1 - 0.76 10.0 5.4 1.8 8.8 3.8 1.7 1 1 0 1 1 1 0 YgaB-like protein Atg14 PF10186.4 KEG15642.1 - 1.2 7.9 5.8 1.3 7.8 4.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SseC PF04888.7 KEG15642.1 - 2.4 7.4 5.0 2.9 7.1 3.5 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family IATP PF04568.7 KEG15642.1 - 2.4 8.2 9.5 33 4.5 6.6 2.2 1 1 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP GTP_EFTU PF00009.22 KEG15643.1 - 3.8e-42 143.8 0.0 5.9e-42 143.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 KEG15643.1 - 1.1e-29 102.5 2.4 2e-29 101.6 1.7 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 KEG15643.1 - 1.6e-16 59.9 0.0 3.8e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.18 KEG15643.1 - 0.00014 21.7 0.0 0.0003 20.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 KEG15643.1 - 0.0043 16.4 0.0 0.0085 15.4 0.0 1.4 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KEG15643.1 - 0.035 13.3 0.0 0.081 12.1 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Peptidase_MA_2 PF13485.1 KEG15643.1 - 0.042 13.8 0.0 0.087 12.8 0.0 1.5 1 0 0 1 1 1 0 Peptidase MA superfamily Miro PF08477.8 KEG15643.1 - 0.056 13.9 0.0 0.098 13.1 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein SNAP PF14938.1 KEG15645.1 - 9.3e-13 47.9 10.0 3.1e-05 23.2 5.8 2.9 2 1 0 2 2 2 2 Soluble NSF attachment protein, SNAP TRAPPC-Trs85 PF12739.2 KEG15645.1 - 0.048 12.3 1.1 0.066 11.8 0.7 1.3 1 1 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Tim44 PF04280.10 KEG15645.1 - 0.051 13.5 0.1 0.096 12.6 0.1 1.5 1 0 0 1 1 1 0 Tim44-like domain TPR_7 PF13176.1 KEG15645.1 - 0.093 12.5 2.5 45 4.1 0.1 4.8 5 1 1 6 6 6 0 Tetratricopeptide repeat NAD_binding_2 PF03446.10 KEG15645.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NSF PF02071.15 KEG15645.1 - 1.6 9.6 7.3 72 4.6 0.3 4.5 3 1 1 4 4 4 0 Aromatic-di-Alanine (AdAR) repeat TPR_2 PF07719.12 KEG15645.1 - 9.9 6.3 6.6 21 5.3 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat DNA_pol_phi PF04931.8 KEG15647.1 - 2.7 5.6 11.3 4.8 4.8 7.9 1.4 1 0 0 1 1 1 0 DNA polymerase phi Nucleo_P87 PF07267.6 KEG15648.1 - 5.1 5.6 3.3 16 4.0 1.5 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 Apt1 PF10351.4 KEG15648.1 - 6 5.6 6.4 11 4.7 4.4 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain HEAT_2 PF13646.1 KEG15650.1 - 9.2e-15 54.7 3.7 0.0026 18.0 0.0 5.9 4 2 3 7 7 7 5 HEAT repeats HEAT PF02985.17 KEG15650.1 - 7.4e-12 44.2 2.9 0.76 10.0 0.0 9.3 11 0 0 11 11 11 3 HEAT repeat HEAT_EZ PF13513.1 KEG15650.1 - 1.7e-10 41.0 9.9 0.05 14.1 0.0 8.1 6 2 3 9 9 9 3 HEAT-like repeat IBN_N PF03810.14 KEG15650.1 - 1.1e-09 38.0 0.5 4.8e-07 29.5 0.0 4.1 5 0 0 5 5 5 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 KEG15650.1 - 5.6e-08 33.0 2.0 0.0032 17.8 0.0 5.3 3 2 3 6 6 6 1 Vacuolar 14 Fab1-binding region Arm PF00514.18 KEG15650.1 - 8.1e-05 22.2 12.3 2.3 8.1 0.1 7.3 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 KEG15650.1 - 0.00015 21.1 0.4 0.16 11.3 0.2 3.4 3 0 0 3 3 3 2 CLASP N terminal Catalase-rel PF06628.7 KEG15650.1 - 0.016 15.0 0.1 0.14 12.0 0.0 2.6 3 0 0 3 3 3 0 Catalase-related immune-responsive MMS19_C PF12460.3 KEG15650.1 - 0.044 12.4 7.1 2.5 6.7 0.2 4.0 4 1 1 5 5 5 0 RNAPII transcription regulator C-terminal Enolase_C PF00113.17 KEG15651.1 - 2.3e-137 456.8 0.7 1.2e-90 303.5 0.0 2.1 1 1 1 2 2 2 2 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 KEG15651.1 - 1.6e-57 193.0 0.0 3e-57 192.2 0.0 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 KEG15651.1 - 0.00013 21.8 0.0 0.00029 20.7 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.6 KEG15651.1 - 0.0011 18.0 0.3 0.0023 16.9 0.1 1.6 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 KEG15651.1 - 0.003 18.0 0.0 0.011 16.2 0.0 2.0 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Ion_trans PF00520.26 KEG15652.1 - 6.1e-101 335.7 97.1 9e-33 113.2 9.5 5.5 5 0 0 5 5 5 5 Ion transport protein ENTH PF01417.15 KEG15653.1 - 0.015 15.1 0.1 0.12 12.2 0.0 2.3 3 0 0 3 3 3 0 ENTH domain DUF626 PF04776.7 KEG15653.1 - 0.023 15.0 0.0 0.048 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF626) Cas_Csa5 PF09702.5 KEG15653.1 - 0.1 12.6 0.1 5.3 7.1 0.0 2.5 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csa5) WD40 PF00400.27 KEG15654.1 - 2.4e-60 198.3 25.5 1.2e-11 43.9 0.3 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Ribosomal_S25 PF03297.10 KEG15656.1 - 5.1e-41 138.9 4.8 5.6e-41 138.8 3.3 1.0 1 0 0 1 1 1 1 S25 ribosomal protein Pup PF05639.6 KEG15659.1 - 9.9 6.7 8.9 0.66 10.5 0.3 2.6 1 1 1 2 2 2 0 Pup-like protein COG6 PF06419.6 KEG15661.1 - 4.8e-34 117.4 0.1 1.6e-31 109.1 0.0 3.0 3 1 0 3 3 3 2 Conserved oligomeric complex COG6 DUF1467 PF07330.7 KEG15661.1 - 0.18 11.6 2.3 0.44 10.3 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1467) RNA_pol_Rpb1_5 PF04998.12 KEG15662.1 - 6.3e-83 278.2 0.0 2.5e-82 276.2 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KEG15662.1 - 1.3e-62 210.5 0.0 2.4e-62 209.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.7 KEG15662.1 - 4.1e-56 190.6 0.0 1.3e-55 189.0 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.13 KEG15662.1 - 5.6e-32 110.6 0.0 1.3e-31 109.4 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 KEG15662.1 - 7.9e-32 109.2 0.0 2e-31 107.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 eIF-5_eIF-2B PF01873.12 KEG15663.1 - 8.5e-32 109.4 0.3 2.1e-31 108.1 0.1 1.7 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.13 KEG15663.1 - 0.0024 17.7 0.0 0.0062 16.4 0.0 1.7 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Vir_act_alpha_C PF10400.4 KEG15663.1 - 0.07 13.5 0.2 1.5 9.2 0.1 2.3 2 0 0 2 2 2 0 Virulence activator alpha C-term DUF3133 PF11331.3 KEG15663.1 - 0.65 9.6 3.4 2.4 7.8 2.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3133) AAA PF00004.24 KEG15664.1 - 1.4e-06 28.5 0.0 0.00011 22.3 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KEG15664.1 - 6.8e-05 22.5 0.6 0.00055 19.6 0.1 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 KEG15664.1 - 0.00012 22.1 0.6 0.00026 21.0 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KEG15664.1 - 0.00037 21.3 0.0 0.00094 19.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KEG15664.1 - 0.00061 19.9 0.0 0.002 18.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain Viral_helicase1 PF01443.13 KEG15664.1 - 0.0029 17.1 0.0 0.0058 16.1 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.9 KEG15664.1 - 0.0036 17.0 0.0 0.0096 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KEG15664.1 - 0.0042 16.9 0.7 0.0091 15.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.1 KEG15664.1 - 0.01 16.1 0.1 0.021 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KEG15664.1 - 0.011 15.3 0.0 0.011 15.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain T2SE PF00437.15 KEG15664.1 - 0.016 14.0 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_11 PF13086.1 KEG15664.1 - 0.017 14.7 0.0 0.099 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KEG15664.1 - 0.021 14.7 0.5 0.057 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KEG15664.1 - 0.026 13.9 0.0 0.061 12.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_25 PF13481.1 KEG15664.1 - 0.028 13.8 0.0 0.068 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KEG15664.1 - 0.028 13.5 0.0 0.07 12.2 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.7 KEG15664.1 - 0.029 14.0 0.0 0.074 12.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 KEG15664.1 - 0.029 14.5 0.0 0.11 12.6 0.0 2.0 2 0 0 2 2 1 0 RNA helicase UPF0079 PF02367.12 KEG15664.1 - 0.098 12.2 0.1 0.39 10.3 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_14 PF13173.1 KEG15664.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KEG15664.1 - 0.19 11.4 0.1 0.74 9.5 0.0 2.0 2 0 0 2 2 2 0 NTPase DS PF01916.12 KEG15665.1 - 1.8e-64 217.7 0.0 2.2e-53 181.3 0.0 3.0 3 0 0 3 3 3 3 Deoxyhypusine synthase START PF01852.14 KEG15666.1 - 2.3e-08 33.6 0.0 3.3e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 START domain PseudoU_synth_1 PF01416.15 KEG15667.1 - 1.5e-19 70.3 0.0 4.9e-10 39.7 0.0 2.8 2 1 0 2 2 2 2 tRNA pseudouridine synthase WD40 PF00400.27 KEG15668.1 - 2.3e-20 71.6 5.6 0.00013 21.7 0.1 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 KEG15668.1 - 0.05 11.7 0.1 6.3 4.7 0.0 2.3 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Mon1 PF03164.9 KEG15669.1 - 6.6e-37 127.0 0.3 6.7e-35 120.4 0.0 2.5 3 0 0 3 3 3 2 Trafficking protein Mon1 Pyr_redox_2 PF07992.9 KEG15670.1 - 1.4e-12 47.9 0.0 3.2e-08 33.6 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEG15670.1 - 1.8e-05 25.0 0.0 0.0084 16.4 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEG15670.1 - 2.8e-05 23.2 0.2 4.6e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 KEG15670.1 - 0.00013 21.0 0.1 0.00044 19.2 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEG15670.1 - 0.00033 20.6 0.2 0.0012 18.8 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.11 KEG15670.1 - 0.00084 18.8 0.1 0.0016 17.8 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 KEG15670.1 - 0.0025 16.3 0.1 0.005 15.3 0.0 1.5 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 KEG15670.1 - 0.0054 15.6 1.7 0.012 14.4 1.0 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 KEG15670.1 - 0.008 15.9 0.0 0.02 14.6 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 KEG15670.1 - 0.016 14.9 0.1 0.027 14.1 0.1 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.13 KEG15670.1 - 0.016 15.1 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Trp_halogenase PF04820.9 KEG15670.1 - 0.021 13.4 0.1 0.032 12.8 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Saccharop_dh PF03435.13 KEG15670.1 - 0.023 13.7 0.1 0.15 11.0 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KEG15670.1 - 0.056 13.5 0.1 0.099 12.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 KEG15670.1 - 0.061 12.3 0.2 0.099 11.6 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.14 KEG15670.1 - 0.096 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.12 KEG15670.1 - 0.18 10.8 0.1 0.31 10.1 0.1 1.2 1 0 0 1 1 1 0 Thi4 family DUF2331 PF10093.4 KEG15671.1 - 0.023 13.4 0.0 0.026 13.3 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2331) Thymidylate_kin PF02223.12 KEG15671.1 - 0.1 11.9 0.3 0.13 11.6 0.2 1.2 1 0 0 1 1 1 0 Thymidylate kinase CDK2AP PF09806.4 KEG15672.1 - 5.6 7.1 11.8 0.085 13.0 2.2 2.1 1 1 1 2 2 2 0 Cyclin-dependent kinase 2-associated protein DUF808 PF05661.7 KEG15673.1 - 0.17 10.6 1.1 0.51 9.1 0.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF808) DUF4544 PF15077.1 KEG15673.1 - 3 7.2 0.0 3 7.2 0.0 5.3 5 1 1 6 6 6 0 Domain of unknown function (DUF4544) zf-C2H2 PF00096.21 KEG15674.1 - 0.00024 21.2 0.9 0.00056 20.0 0.6 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEG15674.1 - 0.001 19.2 1.2 0.0023 18.1 0.8 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-Di19 PF05605.7 KEG15674.1 - 0.0068 16.4 0.1 0.013 15.6 0.1 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Seryl_tRNA_N PF02403.17 KEG15674.1 - 0.031 14.2 0.3 0.031 14.2 0.2 6.4 2 1 3 6 6 6 0 Seryl-tRNA synthetase N-terminal domain Filament PF00038.16 KEG15674.1 - 0.045 13.2 51.4 0.31 10.4 5.2 5.0 2 1 2 4 4 4 0 Intermediate filament protein Ist1 PF03398.9 KEG15675.1 - 1.4e-57 193.6 0.1 1.7e-57 193.4 0.0 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway CS PF04969.11 KEG15676.1 - 2.8e-09 37.3 0.0 4.6e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 CS domain HCV_NS5a_C PF12941.2 KEG15676.1 - 0.083 12.4 0.7 0.13 11.7 0.5 1.3 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region DUF3245 PF11595.3 KEG15676.1 - 5.2 7.3 7.6 3.2 8.0 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) DUF1935 PF09149.5 KEG15677.1 - 1.1e-113 372.3 0.2 5.7e-29 100.1 0.0 4.0 4 0 0 4 4 4 4 Domain of unknown function (DUF1935)